[ { "cls_id": "homologset.agr.FB:FBgn0000014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31267-1", "uniprot_id": "HXA6_HUMAN", "id": "P31267-1", "name": "Homeobox protein Hox-A6", "aln": "MSSYFVN---PTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ-----SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGD------------------------------YLHFSPEQQYKPDSSSGQGKALH--------------------------------------------------------------------------------------------------------------------------DEGADRKYTS------------------------------------------------------------------------PVYPWMQRMNSCAG-----------AVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSG-----EDSEAKAGE-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09092-1", "uniprot_id": "HXA6_MOUSE", "id": "P09092-1", "name": "Homeobox protein Hox-A6", "aln": "MSSYFVN---PTFPGSLPSGQDSFLGQLPLYPAGYDALRPFPASYGASSLPDKTYTSPCFYQQ-----SNSVLACNRASYEYGASCFYSDKDLSGASPSGNNKQRGPGD------------------------------YLHFSPEQQYKPDGS-VQGKALH--------------------------------------------------------------------------------------------------------------------------EEGTDRKYTS------------------------------------------------------------------------PVYPWMQRMNSCAG-----------AVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQASG-----EDSEAKAGE-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29555-1", "uniprot_id": "ABDA_DROME", "id": "P29555-1", "name": "Homeobox protein abdominal-A", "aln": "MSKFVFDSMLPKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTNNSSSSPSSSSNNNSNLNLSGGSLSPSHLSQHLGQSPHSPVSSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDHHSIIAHNPGHLHHSVVGQNDLKLGLGMGVGVGVGGIGPGIGGGLGGNLGMMSALDKSNHDLLKAVSKVNS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:..: *.:* * .. .* * :. . .:.*: .::* . .: :*. .. **: : * :* .:* *: :***.* * . .: *: :**.. :*::: .* . *: :: : :**. * **** : .. . *. *********:************:***********:******************* *** : ::. : .. *:.: ** * ", "identical_positions": 93, "similar_positions": 72, "identity": "15.76%" }, { "cls_id": "homologset.agr.FB:FBgn0000015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9YGT0-1", "uniprot_id": "HXCCB_DANRE", "id": "Q9YGT0-1", "name": "Homeobox protein Hox-C12b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MGEHNLFNPGFVGQLVNINARDAFYLSNFR--------------------------ASGGQLAGLQTLRLSRRDNVCSLPWNPSEACSGYPQS----------------------HISGPVTLN------------HTYNQSCDITR---QEDNKCFYSDSACATSGGGDNNSTNLISKEGALDNSSVSITAENGQNNLNGMDNGGSYSKYDCLTPAEQP-IPNPRLCRSL---------------------ESVSGCSFINEGAKTSSGITHSLTSPDIQTSVAALNGGALWYPMHRQTRKKRKPYSKLQLNELEGEFILNEFITRQRRRELSDRLNLTDQQVKIWFQNRRMKKKRLLMREQALSYF--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90471-1", "uniprot_id": "HXDCA_DANRE", "id": "Q90471-1", "name": "Homeobox protein Hox-D12a", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MCEHNLLSSGYVAPLLNFHSPDSLYLQNLR--------------------------GNGVHLSGLPQMSYSRRE-VCSLPWSSSNSCTAPAQS----------------------RAYSGYSQ-------------PFFSNSAAVSA---SLNT---HKKGSLEESGRYYFQDVSHKSEEPGRPNAAYASEQSSASNGLSNLER----RQLNAVAPNELSCIEQPESDASK---------------------QSVS----------SIAPFQPSLSAQNIRP---AFTDGLPWCPSQVRSRKKRKPYTKPQLTELENEFMMNEFINRQKRKELSDRLELSDQQVKIWFQNRRMKKKRLMMREHTFTIY--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4ACL0-1", "uniprot_id": "D4ACL0_RAT", "id": "D4ACL0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVP--EFSTVSSFLPQ-APSRQIS---------------------------YPYS----AQVPPVREVSY---GLEPSGKWHHRN------------------------SYSSCYAAA-----------DELMHRECLPPS----TVTEILMKNEGSYGGHH--HPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGE-AKGEPEAPP----------------------ASGLASRAEAGAEAEAEEENTNPSSSGSSHSATKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31313-1", "uniprot_id": "HXC11_MOUSE", "id": "P31313-1", "name": "Homeobox protein Hox-C11", "aln": "----------------------------------------------------------------------------------------------------------------------------MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVP--EFSTVSSFLPQ-APSRQIS---------------------------YPYS----AQVPPVREVSY---GLEPSGKWHHRN------------------------SYSSCYAAA-----------DELMHRECLPPS----TVTEILMKNEGSYGGHH--HPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGE-AKGEPEAPP----------------------ASGLASRAEAGAEAEAEEENTNPSSSGSSHSATKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43248-1", "uniprot_id": "HXC11_HUMAN", "id": "O43248-1", "name": "Homeobox protein Hox-C11", "aln": "----------------------------------------------------------------------------------------------------------------------------MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMP--EFSTVSSFLPQ-APSRQIS---------------------------YPYS----AQVPPVREVSY---GLEPSGKWHHRN------------------------SYSSCYAAA-----------DELMHRECLPPS----TVTEILMKNEGSYGGHH--HPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGE-AKGEPEAPP----------------------ASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARL6-1", "uniprot_id": "A0A8M3ARL6_DANRE", "id": "A0A8M3ARL6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------MFNSVNIGNFCSQSRKERTSEFGERASCASNLYLPS-TYYVP--EFSTVSSFLPQ-AQSRQIT---------------------------YSYSTN-FTQVPQVRDLPF---ELNPSGKWHHRG------------------------NYSSCYAE------------EDLVHRDCLPPSA---TMTEMLMKNENVYNHHH-YHPAINHPG-TGFYSSIGKTNVLPQSFDRFLDCAHSG-ADGGSEGNCLQKGSSGKPESASQV----------------------SSVLRSTADGEKELECEKNTTSGSFETSSGTKNDNQTKSGHSTTPRMRKKRCPYTKFQIRELEREFFFNVYINKEKRLQLSRILNLTDRQVKIWFQNRRMKEKKLSRDRLHYFSGNPLM----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q58EL0-1", "uniprot_id": "HXCBA_DANRE", "id": "Q58EL0-1", "name": "Homeobox protein Hox-C11a", "aln": "----------------------------------------------------------------------------------------------------------------------------MFNSVNLGNFCSQTRKDRTSEFGDRTGCASNIYLPSCTYYVP--EFSAVSSFLPQ-GPSRQIT---------------------------YPYSTN-LSQVQPVRDVSY---GLDPSSKWHHRS------------------------NYASCYSG------------EDLVHRDCLPPS----TMTEMLMKNESVYSHHHQHHPNSSHPS-TGFYTGVGKNNVLPQGFDRFFETAYCS-TDNQSE-HCLQKSEMNKLETSSQQ----------------------PTAVSAAREPEKDPEDEEEHTNSGSCTSAATKDGNASKSSHSSTPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V6Z0-1", "uniprot_id": "G3V6Z0_RAT", "id": "G3V6Z0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MMDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMT---------------------------YSYSSN-LPQVQPVREVTFREYAIEPATKWHPRG------------------------NLAHCYSA------------EELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP---AVS---SNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKNAEKGPPTAAATSAAAVAAAATGAPATSSSDGGGGGGCQE--AAAEEKERRRRPESSSSPESSSGHTEDKA-GGSG-GQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31311-1", "uniprot_id": "HXA11_MOUSE", "id": "P31311-1", "name": "Homeobox protein Hox-A11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MMDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMT---------------------------YSYSSN-LPQVQPVREVTFREYAIEPATKWHPRG------------------------NLAHCYSA------------EELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP---AVS---SNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKNAEKGPQAAAATSAAAVAAAATGAPATSSSDGGGGGGCQE--AAAEEKERRRRPESSSSPESSSGHTEDKA-GGSG-GQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31270-1", "uniprot_id": "HXA11_HUMAN", "id": "P31270-1", "name": "Homeobox protein Hox-A11", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMT---------------------------YSYSSN-LPQVQPVREVTFREYAIEPATKWHPRG------------------------NLAHCYSA------------EELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP---AVS---SNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAA-AAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKA-GGSS-GQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDU1-1", "uniprot_id": "HXABB_DANRE", "id": "Q9DDU1-1", "name": "Homeobox protein Hox-A11b", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MMDFDERVPVGSNMYLPGCTYYVSGTDFSSLPPFLPQTPSSCPMT---------------------------YSYSTSSLPQVQSVREVSFRDYAIDTSSKWHSRG------------------------NLPHCYAT------------EDMVHRECLSNP---GTLGDMLSKNN-SVLYHSNS---SHT---SNVYGSVGRNGVLPQAFDQFFETAYGNVENQPTEHPVDRATSKAPPPAESGS------------------------------DSCRGTDETERCEETSSPEPSSGNNEDKF-SGSSNGQKTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYYTTNPLL----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DDU0-1", "uniprot_id": "HXABA_DANRE", "id": "Q9DDU0-1", "name": "Homeobox protein Hox-A11a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MMDFDERVSVGSNMYLPSCTYYVPGADFSTLPSFLSQSPSTRPVT---------------------------YSYASN-LPQVQHVREVTFRDYAIDPSTKWPHRG------------------------PLAHCYPS------------EDSVHKECLPAV---TTVGEMFPKNNASAYYHSTS---NTTSA-SNFYGNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDYAARDKMHSSKQSTPAP------------------------------APEQQPEGKER-PETSSPESSSGNNEEKT-SGANSGPRFRKKRCPYTKFQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKMWFQNRRMKEKKLNRDRLQYYSTNPLL----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AT90-1", "uniprot_id": "A0A8I6AT90_RAT", "id": "A0A8I6AT90-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MNDFDECGPSAASMYLPGCAYYVAPSDFASKPSFLSQ-PSSCQMT---------------------------FPYSSNLAPHVQPVREVAFRDYGLER-AKWPYRGGGGGGAGGGG--GGGPGGGGGGSGGYAPYYAAAAAAAAAAAAAEEAAMQRDLLPPAGR---RPDVLFKAPEPVCGAPGPPHGPAAAA-SNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPQPAPAPPQPEGAADKGDPKAGA---------------GGGGGSPCSKATPGPEPKGAAEGGGGEGEGPPGEAGAEKS-GGTVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23813-1", "uniprot_id": "HXD11_MOUSE", "id": "P23813-1", "name": "Homeobox protein Hox-D11", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MYLPGCAYYVAPSDFASKPSFLSQ-PSSCQMT---------------------------FPYSSNLAPHVQPVREVAFRDYGLER-AKWPYRGGGGGGAGGGG--GGGPGGGGGGSGGYAPYYAAAAAAAAAAAAAEEAAMQRDLLPPAGR---RPDVLFKAPEPVCGAPGPPHGPAAAA-SNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPQPAPAPPQPEGAADKGDPKPGA---------------GGGGGSPCAKATPGPEPKGAAEGGGGEGEGPPGEAGAEKS-GGTVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31277-1", "uniprot_id": "HXD11_HUMAN", "id": "P31277-1", "name": "Homeobox protein Hox-D11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MNDFDECGQSAASMYLPGCAYYVAPSDFASKPSFLSQ-PSSCQMT---------------------------FPYSSNLAPHVQPVREVAFRDYGLER-AKWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGR---RPDVLFKAPEPVCAAPGPPHGPAGAA-SNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGA---------------GGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKS-SSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90470-1", "uniprot_id": "HXDBA_DANRE", "id": "Q90470-1", "name": "Homeobox protein Hox-D11a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MTDYDDRNNCASNMYLP---YYVSTPDFSSVSSFLPQ-TTSCQVN---------------------------FPYSSNIA-QVQPVREVTFRDYGLDHPSKWHYRG------------------------NYASYYST------------EEIMHRDLLQSTN----RAEMIFKNDSMYSHHAG-----TNSS-CSFFTNVGRNGVLPQGFDQFFETAN---------SEKPNPEQSKQKPDTSVP----------------------GDAACNPSTDSAEQTKQDPTDTVEEESSVSTCDEEKN-SGSSATK-SRKKRCPYSKYQIRELEREFFFNVYINKEKRLQLSRMLSLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZHM5-1", "uniprot_id": "D3ZHM5_RAT", "id": "D3ZHM5-1", "name": "", "aln": "-----------------------------------------------------MSARKGYLLPSPNYPTTMSCSES-PAANSFLVDSLISSGRGEAGGGGGSAGGGGGG-YYAHGGVYLPPASDLP--YGLQSCGLFPALGNKRNEAPSPGGGGGGGGGGLGPGAHGYAPAPLDLWLDAPRSCRMEPPDGPPPPQPQPQQQQQ-PPPPPPQPPQPPPQATSCSFAQN-IKEESSYCLYDSADKCPKGSA----------------------AADLAPFPRG-------------PPPDGCALGASSG-VPVPGYFRLSQAYGTAKGFGSGG--TQQLAS-PFPAQPPGRGFDPPSALASGSAEAAGKERVLDSTPPPTLVCAGGGSSQ-------------------ADEEAHASSSAAEELSPAPSENSKASPEKDSLGNSKSEN-AANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31310-1", "uniprot_id": "HXA10_MOUSE", "id": "P31310-1", "name": "Homeobox protein Hox-A10", "aln": "-----------------------------------------------------MSARKGYLLPSPNYPTTMSCSES-PAANSFLVDSLISSGRGEAGVGGGSAGGGGGG-YYAHGGVYLPPASDLP--YGLQSCGLFPALGSKRNEAPSPGGGGGGGSGGLGPGTHGYAPAPLDLWLDAPRSCRMEPPDGPPPPQPQPQQQQQQPPPPPPQPPQPQPQATSCSFAQN-IKEESSYCLYDAADKCPKGSA----------------------AADLAPFPRG-------------PPPDGCALGASSG-VPVPGYFRLSQAYGTAKGFGSGGGGTQQLAS-PFPAQPPGRGFDPPPALASGSTEAAGKERVLDSTPPPTLVCTGGGGSQ-------------------GDEEAHASSSAAEELSPAPSENSKASPEKDSLGSSKGEN-AANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31260-1", "uniprot_id": "HXA10_HUMAN", "id": "P31260-1", "name": "Homeobox protein Hox-A10", "aln": "-----------------------------------------------------MSARKGYLLPSPNYPTTMSCSES-PAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLP--YGLQSCGLFPTLGGKRNEAASPGSGGGGG--GLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPP-PQQQ------PPPPPQPPQPAPQATSCSFAQN-IKEESSYCLYDSADKCPKVSAT---------------------AAELAPFPRG-------------PPPDGCALGTSSG-VPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQ-------------------GDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGEN-AANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AWY2-1", "uniprot_id": "HXAAB_DANRE", "id": "Q8AWY2-1", "name": "Homeobox protein Hox-A10b", "aln": "----------------------------------------------------------------------MSCSDS-PSGNSFLVDSLIH-GRSE-----------GSGHYYQNSGVYLQPTSEYS--YGLSNCGYFSGL--KRNESNSQN---------VVPTCGPYQG--METWLETSRSCRIE---------------------------QPNSQITPRSFSPT-IKEENSYCLYES-EKCPKETI----------------------TEDIS-YSR--------------LTPNSCPSSNNNGCVPVPGYFRLSQTCTTSKGFTDNQTIPTHVVA-----QRSTR-FD--SSLSAIAAEASRDE---SDEPPTCAPCAPG-----------------------RNKELRGSTGTAS--SPEPPDSPEKAVTVTKAGDSKSES-TANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMSRENRIRELSANFSFS--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28358-1", "uniprot_id": "HXD10_HUMAN", "id": "P28358-1", "name": "Homeobox protein Hox-D10", "aln": "----------------------------------------------------------------------MSFPNSSPAANTFLVDSLISACRSDS-------------FYSSSASMYMPPPSADMGTYGMQTCGLLPSL-AKR-EVNHQN---------MGMNVHPYIP-QVDSWTDPNRSCRIEQ--------------------------PVTQQVPTCSFTTN-IKEESNCCMYSD--KRNKLIS-----------------------AEVPSYQR--------------LVPESCPVE--NPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTV----MLQLNPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVE------------------------SPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4ACD8-1", "uniprot_id": "D4ACD8_RAT", "id": "D4ACD8-1", "name": "Homeobox protein Hox-D10", "aln": "MSLLSVLPRPAGRAVEHVTCKEAAAQGHFQISLAWLSCGRQRHPQLHRECFPSDVSLQRTQSLFFKFLPKMSFPNSSPAANTFLVDSLISACRSDS-------------FYSSSASMYMPPPSADMGTYGMQTCGLLPSL-AKR-EVNHQN---------MGMNVHPYIP-QVDSWTDPNRSCRIEQ--------------------------PVTQQVPTCSFTAN-IKEESNCCMYSD--KRNKLIS-----------------------AEVPSYQR--------------LVPESCPVE--NPEVPVPGYFRLSQTYATGKTQEYNNNPEGSSTV----MLQLNPRGAAKPQLSAAQLQMEKKMNETASGQEPTKVSQVE------------------------SPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28359-1", "uniprot_id": "HXD10_MOUSE", "id": "P28359-1", "name": "Homeobox protein Hox-D10", "aln": "----------------------------------------------------------------------MSFPNSSPAANTFLVDSLISACRSDS-------------FYSSSASMYMPPPSADMGTYGMQTCGLLPSL-AKR-EVNHQN---------MGMNVHPYIP-QVDSWTDPNRSCRIEQ--------------------------PVTQQVPTCSFTAN-IKEESNCCMYSD--KRNKLIS-----------------------AEVPSYQR--------------LVPESCPVE--NPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTV----MLQLNPRGAAKPQLSAAQLQMEKKMNESASGQEPTKVSQVE------------------------SPEAKGGLPEDRSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90469-1", "uniprot_id": "HXDAA_DANRE", "id": "Q90469-1", "name": "Homeobox protein Hox-D10a", "aln": "----------------------------------------------------------------------MSFPNSSPAANTFLVDSLIGACRTD--------------FYSSSN-MYMPAATAEMGTYGMQTCGLLPAL-GKRGEVNHQN---------MDMTVHSYIP-QTDTWADPSRSCRLEQ--------------------------PLN-QMSTCTFSQS-IKEETNCCMYSD--KRAKVSS-----------------------SEIPAYSS--------------LIPESCSVD--SPEIPVPGYFRLSQTYATAKNPDYDNETMSPNTT----LMQLN-RATPKAQ-STPFVEVEKKL---AHDRDTRSSSPAQ------------------------SPEPKVSTLEEKNCSTEASVSSPELPHREGKE-SKNDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTSNLTFS--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V815-1", "uniprot_id": "G3V815_RAT", "id": "G3V815-1", "name": "Homeobox protein Hox-C10", "aln": "----------------------------------------------------------------------MTCPRN-VTPNSYAEPLAAPGG---------------GERYNRSAGMYMQSGSDFN-CGVMRGCGLAPS-LSKRDEGGSPN-------LALNTYPS--YLSQLDSWGDPKAAYRLEQ--------------------------PVGRPLSSCSYPPS-VKEENVCCMYSAEKR-AK-SG------------------------PEAALYSH-------------PLPESCLGE---HEVPVPSYYRASPSYSALDKTPHCAGANEFEAP----FEQRASLNPRTEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQ-------------------SLVGPKASPSESEKERAKTADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31257-1", "uniprot_id": "HXC10_MOUSE", "id": "P31257-1", "name": "Homeobox protein Hox-C10", "aln": "----------------------------------------------------------------------MTCPRN-VTPNSYAEPLAAPGG---------------GERYNRNAGMYMQSGSDFN-CGVMRGCGLAPS-LSKRDEGGSPN-------LALNTYPS--YLSQLDSWGDPKAAYRLEQ--------------------------PVGRPLSSCSYPPS-VKEENVCCMYSAEKR-AK-SG------------------------PEAALYSH-------------PLPESCLGE---HEVPVPSYYRASPSYSALDKTPHCAGANEFEAP----FEQRASLNPRTEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQ-------------------SLAGPKASPSESEKERAKTADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYD6-1", "uniprot_id": "HXC10_HUMAN", "id": "Q9NYD6-1", "name": "Homeobox protein Hox-C10", "aln": "----------------------------------------------------------------------MTCPRN-VTPNSYAEPLAAPGG---------------GERYSRSAGMYMQSGSDFN-CGVMRGCGLAPS-LSKRDEGSSPS-------LALNTYPS--YLSQLDSWGDPKAAYRLEQ--------------------------PVGRPLSSCSYPPS-VKEENVCCMYSAEKR-AK-SG------------------------PEAALYSH-------------PLPESCLGE---HEVPVPSYYRASPSYSALDKTPHCSGANDFEAP----FEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQ-------------------SLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NI81-1", "uniprot_id": "F6NI81_DANRE", "id": "F6NI81-1", "name": "", "aln": "----------------------------------------------------------------------MSCPNN-VAANAFLMDSLVGGTSPFR-----------GESYSSNSGMYMQTSAEYG-CSMMGSFGIVGTPLSKRDDLQPSG-------MHLGSYQHSHYLSQRDTWIAGSKTYRGSQ--------------------------PVAQPLHPCSFPASNVKEEAIPCLYQPDIDSAKESG------------------------EKSTYIRL-------------GDNNSHPNQ---SAVSTPDYFRRSQVYAS--ERGHHG--DEFGSD----FNPIPRISTPVEALASD------SCVKSSKAR-QHPEDKGGNTQE-------------------DDMDQRQTRKE---ESVSKTESCTDDSESELKDESKLEKATGNWLKAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSINLTDRQVKIWFQNRRMKLKKLNRESRVRELTG-YSFN--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9PWL7-1", "uniprot_id": "HXBAA_DANRE", "id": "Q9PWL7-1", "name": "Homeobox protein Hox-B10a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MALHRHPFVHGAASWDGEQPSPVQLPH-------------------------------ISACPFTSSGRKEDPFYFTLDPTGQARQPLD-------------------------ISAFSRI-------------MTDMGSLNS-ADDHRPETSFYSGHKLLSLNTDTDPESPSLSSHSD--SQHLHSLSLSAPCSETDNKHDMQYLAMESTKYPSQWSESRTNRSIIT-------------------TLSISQRSKDDIEPNNLQTDFTRGDKTPREKTQDVTLENAANGWLSAKAGRKKRCPYSKHQILELEKEFLFNMYLTRERRLEISRSINLTDRQVKIWFQNRRMKLKKMTREHRTRDPGTSFTV---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZW24-1", "uniprot_id": "D3ZW24_RAT", "id": "D3ZW24-1", "name": "Homeobox protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSISGTLSSYYVDSIISHESEDAPPAKFPS---------------------------GQYAN--PRQPGHAEHLDFPSCSFQPKAPVFGAS-----------------------------WAPL-------------SPHASGSLP------------SVYHPYLQ-PQGAPAAESRYLRTW-----LEPAPRA--EAAPGQGQAAVKAEP-LLGAPGELLK---QGTPEY-------------------SLETSAGREAVLSNQRAGYGDNK-ICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20615-1", "uniprot_id": "HXB9_MOUSE", "id": "P20615-1", "name": "Homeobox protein Hox-B9", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSISGTLSSYYVDSIISHESEDAPPAKFPS---------------------------GQYAN--PRQPGHAEHLDFPSCSFQPKAPVFGAS-----------------------------WAPL-------------SPHASGSLP------------SVYHPYLQ-PQGAPAAESRYLRTW-----LEPAPRA--EAAPGQGQAAVKAEP-LLGAPGELLK---QGTPEY-------------------SLETSAGREAVLSNQRAGYGDNK-ICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17482-1", "uniprot_id": "HXB9_HUMAN", "id": "P17482-1", "name": "Homeobox protein Hox-B9", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSISGTLSSYYVDSIISHESEDAPPAKFPS---------------------------GQYAS--SRQPGHAEHLEFPSCSFQPKAPVFGAS-----------------------------WAPL-------------SPHASGSLP------------SVYHPYIQ-PQGVPPAESRYLRTW-----LEPAPRG--EAAPGQGQAAVKAEP-LLGAPGELLK---QGTPEY-------------------SLETSAGREAVLSNQRPGYGDNK-ICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PWM2-1", "uniprot_id": "HXB9A_DANRE", "id": "Q9PWM2-1", "name": "Homeobox protein Hox-B9a", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSISGTLSNYYVDSIISHEGEDPNASRFSN---------------------------VQYSS--ARQPGPGEHPEFPSCSFQPKPPVFSSS-----------------------------WSPF-------------SSHASNGLP------------AVYHPYIP-TQPVPSTDTRYLRTW-----LDCAPRA--EPLPGQGQ--VKMEP-LLGHLGEPPKL--VGQHEY-------------------ILESSTAREIN-SGHSAGFEDNKDICEGSEDKEGPDQNDPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLTERQVKIWFQNRRMKMKKMNKDQPKE-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9YGT5-1", "uniprot_id": "HXA9B_DANRE", "id": "Q9YGT5-1", "name": "Homeobox protein Hox-A9b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLGTLS-YYADSHIPHENDDHLAPRFSS---------------------------GPVVQQQSRELTLLEYSEQEPYTFQAKSSIFGAS-----------------------------WSPV-------------QPTGAS---------------IAYHPYIHHPCSTGDSDGASVRPWA----LEPLPALPFTGLSTDTHQDIKLEP-LVGS-GECTTHTLLVAETD-------------------NNTTQTERKVPDDAVSNGSHDEK---IPAETKLDLDPNNPSSNWLHAKSTRKKRCPYTKHQTLELEKEFLFNMYLSRDRRYEVARLLNLTERQVKIWFQNRRMKMKKCNKDRPKDI----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9PWL6-1", "uniprot_id": "HXA9A_DANRE", "id": "Q9PWL6-1", "name": "Homeobox protein Hox-A9a", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSTSGALTGYYVDSIVIPGSEE---TRFSS---------------------------GLGLIQHRPTILPADLSDLGPCTFPAKQPVYGTSD----------------------------WGHI-------------PTHFSTGVP------------SVYQPHAQ-----PPVVGDYVQSWL----LDSACGLPQTEPPTVNHNHAKSDTNETNDDGTEYSP--HTILQP-------------------EVFTNGGCSTKTEAESSRTAEKS---GDIEGKPGADPENPVSNWLHASSTRKKRCPYTKHQILELEKEFLFNTYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKFNKNETKED----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "----------------------MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASG------ASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKED----------------------INMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEP--------------------PTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** **:* * *** **::. ::.:::* ::: : *:::***:******** *: ", "identical_positions": 27, "similar_positions": 19, "identity": "4.8%" }, { "cls_id": "homologset.agr.FB:FBgn0000017", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT20-1", "uniprot_id": "E9PT20_RAT", "id": "E9PT20-1", "name": "Tyrosine-protein kinase", "aln": "MGQQPGKVLGDQR----------RPSLPALHFIKGAGKRDSSRHGGPHC----------------NVFVEH------------EALQRPVASDFEPQG--------------------------------------------------------------------LSEAARWNSKENLLAG-PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNG-QGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVAD--GLITTLHYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGK--RGMRG-AAGSTLQAPELPTKTRTCRKTAEQKD----APDALELLHTKGLGESDALDSEP-AVSPLLPRKERGPPDGSLNED--ERLLPKDKKTNLFSALIKKKKKMAPTPPKRS--------SSFREMDGQSERR-----------------GASEDDGREISNGPPALT--SDAVEP-----------TKSPKASNGAGVPNGAFRE--PGNSGFRSPH----------------------------------------VWKKSSTLTSSRLAAAEEESGLSSSKRFLRSCSASCMPHGVRDTEWRSVTLPRDLPSA----------------------------------------------GKQFDSSTFGGHKSEKPALPR--KRTSESRSEQ-VAKSTA-------------------------TPPPRLVKKTEEAAEDVFK-----DTE-SSPGSSPPS---------------------LTPKLLRRQVPASPSSGPSHKDEATKGNASGMGTPATAEPAAPSNKAG------LSKASSEEPRARRHKHSSESPGRDKGRLS-----------KLKPAPPPPPSS-TGKAG------------------KPAQSPSQDVAGEAGGATKTKCTSLSVDAVNSDP----------------------TKAGQPGEG----------------------------------------------------------LRKSVPPSVPKPQSATKPPGTPTSPVSTPSTAPAPSP---------------------------------------LAGDQQPSSAAFIPLISTRVSLR--------------------KTRQPPERIASGTITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKN--LYTFCVSYVDS-IQQMRNKFAFREAINKLESNLRELQICPATASSGPAATQDFSKLLSSVKEISDIVRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00520-1", "uniprot_id": "ABL1_MOUSE", "id": "P00520-1", "name": "Tyrosine-protein kinase ABL1", "aln": "MLEICLKLVGCK-----------------------------SKKGLSSS----------------SSCYLE------------EALQRPVASDFEPQG--------------------------------------------------------------------LSEAARWNSKENLLAG-PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNG-QGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVAD--GLITTLHYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGK--RGTRG-GAGSMLQAPELPTKTRTCRRAAEQKD----APDTPELLHTKGLGESDALDSEP-AVSPLLPRKERGPPDGSLNED--ERLLPRDRKTNLFSALIKKKKKMAPTPPKRS--------SSFREMDGQPDRR-----------------GASEDDSRELCNGPPALT--SDAAEP-----------TKSPKASNGAGVPNGAFRE--PGNSGFRSPH----------------------------------------MWKKSSTLTGSRLAAAEEESGMSSSKRFLRSCSASCMPHGARDTEWRSVTLPRDLPSA----------------------------------------------GKQFDSSTFGGHKSEKPALPR--KRTSESRSEQ-VAKSTA-------------------------MPPPRLVKKNEEAAEEGFK-----DTE-SSPGSSPPS---------------------LTPKLLRRQVTASPSSGLSHKEEATKGSASGMGTPATAEPAPPSNKVG------LSKASSEEMRVRRHKHSSESPGRDKGRLA-----------KLKPAPPPPPAC-TGKAG------------------KPAQSPSQ-EAGEAGGPTKTKCTSLAMDAVNTDP----------------------TKAGPPGEG----------------------------------------------------------LRKPVPPSVPKPQSTAKPPGTPTSPVSTPSTAPAPSP---------------------------------------LAGDQQPSSAAFIPLISTRVSLR--------------------KTRQPPERIASGTITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKN--LYTFCVSYVDS-IQQMRNKFAFREAINKLESNLRELQICPATASSGPAATQDFSKLLSSVKEISDIVRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00519-1", "uniprot_id": "ABL1_HUMAN", "id": "P00519-1", "name": "Tyrosine-protein kinase ABL1", "aln": "MLEICLKLVGCK-----------------------------SKKGLSSS----------------SSCYLE------------EALQRPVASDFEPQG--------------------------------------------------------------------LSEAARWNSKENLLAG-PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNG-QGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVAD--GLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGK--QGVRG-AVSTLLQAPELPTKTRTSRRAAEHRD----TTDVPEMPHSKGQGESDPLDHEP-AVSPLLPRKERGPPEGGLNED--ERLLPKDKKTNLFSALIKKKKKTAPTPPKRS--------SSFREMDGQPERR-----------------GAGEEEGRDISNGALAFTP-LDTADP-----------AKSPKPSNGAGVPNGALRE--SGGSGFRSPH----------------------------------------LWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQST----------------------------------------------GRQFDSSTFGGHKSEKPALPR--KRAGENRSDQ-VTRGTV-------------------------TPPPRLVKKNEEAADEVFK-----DIMESSPGSSPPN---------------------LTPKPLRRQVTVAPASGLPHKEEAGKG--SALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLS-----------RLKPAPPPPPAASAGKAGG-----------------KPSQSPSQEAAGEAVLGAKTKATSL-VDAVNSDA----------------------AKPSQPGEG----------------------------------------------------------LKKPVLPATPKPQ-SAKPSGTPISPAPVPSTLPSASS---------------------------------------ALAGDQPSSTAFIPLISTRVSLR--------------------KTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKN--LYTFCVSYVDS-IQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LAB0-1", "uniprot_id": "A0ABK0LAB0_RAT", "id": "A0ABK0LAB0-1", "name": "Tyrosine-protein kinase", "aln": "MGQQVGRVGEAPG----------LQQPQPRGIRGSSAARPSGRRRDPVGRTADAGFNVFTQHDHFASCVEDGFEGDKTGGSSPEVLHRPFGCDAESQA--------------------------------------------------------------------LNEAIRWSSKENLLG--ATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFSTLAELVHHHSTVAD--GLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGR--TASSSSVVPYLPRLPLLPSKTRTLKKQGENKENLDGGLDASEILASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRN--APMPPKRS--------SSFREMENQPHKKYELTGNFSPVASLQHADGFSFTPGQQESNLVPAKCYGGSFAQR-----------NLCGDDDSGGGGGSGTAAGGWSGITGFFTPR----------------------------------------LIKKTLGLRAGKPTASDD-----TSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRS----------------------------------------------KLQLERTVSTSSQPEENVDRA--NDMLPKKSEEGAAPARE-------------------------RPKAKLLPRGATALALRAP--DPAITESDCPGVGVAG---------------------VAAAPKGKERNGGTRLGVAGVPEDAEQ--PGWSSPAKAVAVLPTTHNH--------KVPVLISPTLKHTAADVQLIGTDSQGN-----------KFKLLSEHQVTSSGDKDRPR--------------RVKPKCAPPPPPVMRLLQHPSTCSDPEEEPTAPPAG----------------------QHTPDTQDG----------------------------------------------------------GKKAAPGPVPSSGKPGRP-VMPPPQVPLPTSSISPAK---------------------------------------MANGTAG----------TKVALR--------------------KTKQAAEKISADKISKAALLECAGLLSSAITEP----VPHSQLVDTGHQ--LLHYCSGYVDC-IPHTRNKFAFREAVSKLELSLQELQVSSTAAG-VPGTNPVLNNLLSCVQEISDVVQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4JIM5-1", "uniprot_id": "ABL2_MOUSE", "id": "Q4JIM5-1", "name": "Tyrosine-protein kinase ABL2", "aln": "MGQQVGRVGEAPG----------LQQPQPRGIRGSSAARPSGRRRDPAGRTADAGFNVFTQHDHFASCVEDGFEGDKTGGSSPEVLHRPFGCDAESQA--------------------------------------------------------------------LNEAIRWSSKENLLG--ATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFSTLAELVHHHSTVAD--GLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTFKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGR--TASSSSVVPYLPRLPLLPSKTRTLRKQGENKENLDGGLDAAESLASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRN--APTPPKRS--------SSFREMENQPHKKYELTGNFSPVASLQNADGFSVAPSQQEPNLVPAKCYGGSFAQR-----------NLCADDDSGGGGGSGTAGGGWSGITGFFTPR----------------------------------------LIKKTLGLRAGKPTASDD-----TSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRS----------------------------------------------KLQLERTVSTSSQPEENVDRA--NDMLPKKSEEGAAPARE-------------------------RPKAKLLPRGATALPLRAP--DPAITESDSPGVGVAG---------------------VAAAPKGKERNGGTRLGVAGVPEDGEQ--LGWSSPAKAVAVLPTTHNH--------KVPVLISPTLKHTPADVQLIGTDSQGN-----------KFKLLSEHQVTSSGDKDRPR--------------RVKPKCAPPPPPVMRLLQHPSTCSDPEEEPTAPPAG----------------------QHTPETQEG----------------------------------------------------------GKKAAPGPVPSSGKPGRP-VMPPPQVPLPTSSISPAK---------------------------------------MANGTAG----------TKVALR--------------------KTKQAAEKISADKISKEALLECADLLSSAITEP----VPNSQLVDTGHQ--LLDYCSGYVDS-IPQTRNKFAFREAVSKLELSLQELQVSSTAAG-VPGTNPVLNNLLSCVQEISDVVQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42684-1", "uniprot_id": "ABL2_HUMAN", "id": "P42684-1", "name": "Tyrosine-protein kinase ABL2", "aln": "MGQQVGRVGEAPG----------LQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGCDVEPQA--------------------------------------------------------------------LNEAIRWSSKENLLG--ATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVAD--GLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGR--AASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPG-FIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRN--APTPPKRS--------SSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQR-----------NLCNDD-GGGGGGSGTAGGGWSGITGFFTPR----------------------------------------LIKKTLGLRAGKPTASDD-----TSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRS----------------------------------------------KLQLERTVSTSSQPEENVDRA--NDMLPKKSEESAAPSRE-------------------------RPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAG---------------------VAAAPKGKEKNGGARLGMAGVPEDGEQ--PGWPSPAKAAPVLPTTHNH--------KVPVLISPTLKHTPADVQLIGTDSQGN-----------KFKLLSEHQVTSSGDKDRPR--------------RVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAG----------------------QSTSETQEG----------------------------------------------------------GKKAALGAVPISGKAGRP-VMPPPQVPLPTSSISPAK---------------------------------------MANGTAG----------TKVALR--------------------KTKQAAEKISADKISKEALLECADLLSSALTEP----VPNSQLVDTGHQ--LLDYCSGYVDC-IPQTRNKFAFREAVSKLELSLQELQVSSAAAG-VPGTNPVLNNLLSCVQEISDVVQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00522-1", "uniprot_id": "ABL_DROME", "id": "P00522-1", "name": "Tyrosine-protein kinase Abl", "aln": "MGAQQGKDRGAHSGGGGSGAPVSCIGLSSSPVASVSPHCISSSSGVSSAPLGGGSTLRGSRIKSSSSGVASGSGSGGGGGGSGSGLSQRSGGHKDARCNPTVGLNIFTEHNEALLQSRPLPHIPAGSTAASLLADAAELQQHQQDSGGLGLQGSSLGGGHSSTTSVFESAHRWTSKENLLAPGPEEDDPQLFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHSDSGNVGWVPSNYVTPLNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQESSITEAVEKQLNANATSASSSAPSTSGVATGGGATTTTAASGCASSSSATASLSLTPQMVKKGLPGGQALTPNAHHNDPHQQQASTPMSETGSTSTKLSTFSSQGKGNVQMRRTTNKQGKQAPAPPKRTSLLSSSRDSTYREEDPANARCNFIDDLSTNGLARDINSLTQRYDSETDPAADPDTDATGDSLEQSLSQVIAAPVTNKMQHSLHSGGGGGGIGPRSSQQHSSFKRPTGTPVMGNRGLETRQSKRSQLHSQAPGPGPPSTQPHHGNNGVVTSAHPITVGALDVMNVKQVVNRYGTLPKGARIGAYLDSLEDSSEAAPALPATAPSLPPANGHATPPAARLNPKASPIPPQQMIRSNSSGGVTMQNNAAASLNKLQRHRTTTEGTMMTFSSFRAGGSSSSPKRSASGVASGVQPALANLEFPPPPLDLPPPPEEFEGGPPPPPPAPESAVQAIQQHLHAQLPNNGNISNGNGTNNNDSSHNDVSNIAPSVEEASSRFGVSLRKREPSTDSCSSLGSPPEDLKEKLITEIKAAGKDTAPASHLANGSGIAVVDPVSLLVTELAESMNLPKPPPQQQQKLTNGNSTGSGFKAQLKKVEPKKMSAPMPKAEPANTIIDFKAHLRRVDKEKEPATPAPAPATVAVANNANCNTTGTLNRKEDGSKKFSQAMQKTEIKIDVTNSNVEADAGAAGEGDLGKRRSTGSINSLKKLWEQQPPAPDYATSTILQQQPSVVNGGGTPNAQLSPKYGMKSGAINTVGTLPAKLGNKQPPAAPPPPPPNCTTSNSSTTSISTSSRDCTSRQQASSTIKTSHSTQLFTDDEEQSHTEGLGSGGQGSADMTQSLYEQKPQIQQKPAVPHKPTKLTIYATPIAKLTEPASSASSTQISRESILELVGLLEGSLKHPVNAIAGSQWLQLSDKLNILHNSCVIFAENGAMPPHSKFQFRELVTRVEAQSQHLR--SAGSKNVQDNERLVAEVGQSLRQISNALNR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . * : . . :.: :..* **.******. . *.**:******** *.*:* **:.***::*:*.**:.***.*.::..* *******:**:************:**.******** **************** ***************. .*.*::*: *::*.**********. : **:*.* ***** ****:: :** *:**: **** ************** .***:*. ******:***** :::**:***:***:********:**** ******:**:*.:*****:**...*: : **.********:*.*.***.:*:*************:*::********:*** .*******************.****.** ***********************.***::**. *:*.****:* *** :**:*** **:*..:***:* . *:*:* **::***:: * ::*. . . . :.* * . . .. :. .* : . . . . . .:.: : :*: ** ****: *::** : : .. . : . ..* .* :.* * : ..: : . . : : :. .. . : . : :** * . :. . . .:* . .: . * . . * . . . :: . . * : ..* .. .: . . . : ::* :. * * :*. . . . . :* . . * :* * . . :: :.: . : :: * :... :: *:: :*: . * ::.. . . : :.: * * :.: :.** *** :.::* . :.*: .: : . :: ..:::**: :.*", "identical_positions": 379, "similar_positions": 277, "identity": "23.37%" }, { "cls_id": "homologset.agr.FB:FBgn0000018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EXD0-1", "uniprot_id": "F7EXD0_RAT", "id": "F7EXD0-1", "name": "", "aln": "MSQDSTDVIMDHHVSTIKPRRIQNQNVIHRLERRRISSGRAG------THWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQG--CQAAEDLLQGYEGEILSNGNDQRSVSIRGRLFERFFVLLHITNVAANG---EHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFYEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDG--SAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTS-EDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0A0-1", "uniprot_id": "DET1_MOUSE", "id": "Q9D0A0-1", "name": "DET1 homolog", "aln": "---------MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAG------THWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQG--CQAAEDLLQGYEGEILSNGNDQRSVSIRGRLFERFFVLLHITNVAANG---EHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFYEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDG--SAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTS-EDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L5Y6-1", "uniprot_id": "DET1_HUMAN", "id": "Q7L5Y6-1", "name": "DET1 homolog", "aln": "---------MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAG------THWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQG--CQAAEDLLQGYEGEILSNGNDQRSVNIRGRLFERFFVLLHITNVAANG---EHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDG--SAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTS-EDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKM4-1", "uniprot_id": "Q9VKM4_DROME", "id": "Q9VKM4-1", "name": "", "aln": "---------------MAYKKRLQSQNLVHLLQNRESGYTNVGQQPGRMPLLAYERLFYKCITPCLTIDSITIPPIYLRKFTPDGRKLLAFSQDQRSLLIYSYGGSSCAAVGELIR-QADVGSGECFSSQDTILKSRIFERLFPTKETLNLCQGDFGLYYLHREFSVFLEEGRYAMLAAMTVVRGALPVDDYVRYP-----DLFDKVDAFSYVFFLVDLKLGVVTDRLILPNDSIVIAHNHGISVFGSTVMMMSRLHQCVYVYWVN-DGKFHQQETIG---PRPRDFIEKATTDFDNLDATTVLP-------ITHIKQRVLSFLYRKINDKSGNPTESQKSFYKNFEYIEHMIMERMHLVNNELLMLRYEERPNGTDTMPMATSPRRLYVFYTITGEEVVGVYPEYSVNLLQILLQFNDYMSND---RSLQFGDAPS---LPMHFFLRHTFADSNESVSVDRHTALRFNPSVPLSSQSLSSSPYLKFNEFRYDSRYVSPLEQPHRCCNDPIVFLDRATDSIKFRLHATARRHLNPLAPRELCAFIWHPFDPLVLSIQKCMNSYVYHVHLYNHSTIVEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:*.**::* *:.*. . ..* . *:*:: : * :*: .: ** :****:**** ::***.** ** **.* * * *. :*:: . .: ..:.. ::.*:***:* . *:. .. :*:** *:* :: * .::.: : : . : * : .* :.::**: * : * : *.:*::**:*: :: . : ::* :* ::*: *. :*.* : .*** . : .*. : *: * :. *. :*:*:* :*:*: ::.. .: ::: *:: *: :.:: * :*:*:::: *:::* . : . .* ::*.*.:. **:.*: : * :**::: :* * : * .:** :.* :. :: *.. : * . . . .:. *: .:*:*:** *.****.:. * **.::** :*:*: * :.** * * :. :**.::* : : *.* ** :***:*:.:*:*: .** :.*: : .* ", "identical_positions": 140, "similar_positions": 208, "identity": "24.26%" }, { "cls_id": "homologset.agr.FB:FBgn0000022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19360-1", "uniprot_id": "ASCL2_RAT", "id": "P19360-1", "name": "Achaete-scute homolog 2", "aln": "-MESHFNWYGVPRLQKASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCGAPKPVAGAPALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPELLR-----CSRRR---RSGATEA-------SSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALSGGLLTPATRPSDVCTQPSASPASASLSCTSTSP--DRLGCSEPASPRSAYSSEDSSCEGETYPMG-QMFDFSNWLGGY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35885-1", "uniprot_id": "ASCL2_MOUSE", "id": "O35885-1", "name": "Achaete-scute homolog 2", "aln": "-MEAHLDWYGVPGLQEASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDGGALPRLMPTSSGVAGACAARRRQASPELLR-----CSRRR---RSGATEA-------SSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALAGGLLTPATPPSDECAQPSASPASASLSCASTSPSPDRLGCSEPTSPRSAYSSEESSCEGELSPMEQELLDFSSWLGGY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99929-1", "uniprot_id": "ASCL2_HUMAN", "id": "Q99929-1", "name": "Achaete-scute homolog 2", "aln": "---------------------------------------------------------------------MDGGTLPRSAPPAPPVPVGCAARRRPASPELLR-----CSRRR---RPATAET-------GGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSP--GRGGSSEPGSPRSAYSSDDSGCEGALSPAERELLDFSSWLGGY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90259-1", "uniprot_id": "ASL1A_DANRE", "id": "Q90259-1", "name": "Achaete-scute homolog 1a", "aln": "-MDITAKMEISVNQQQ-----FMPP-ACFFAS---------------------------------QSIQLSP-TDSQCS---NKSASKQAKRQRSSSPELLR-----CKRRLNFAGFGYSLP-------QQQPHAVARRNERERNRVKLVNNGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISQNYSNDM-----------------------NSMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02067-1", "uniprot_id": "ASCL1_MOUSE", "id": "Q02067-1", "name": "Achaete-scute homolog 1", "aln": "-MESSGKMESGAGQQPQPPQPFLPPAACFFATAAAAA--------AAAAAAAQSAQQQQPQAPPQQAPQLSPVADSQPSGGGHKSAAKQVKRQRSSSPELMR-----CKRRLNFSGFGYSLP-------QQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDL-----------------------NSMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90260-1", "uniprot_id": "ASL1B_DANRE", "id": "Q90260-1", "name": "Achaete-scute homolog 1b", "aln": "-MEATVVATTQLTQDSFYQP-------------------------------------------------FSESLEKQDR------ECKVLKRQRSSSPELLR-----CKRRLTFNGLGYTIP-------QQQPMAVARRNERERNRVKQVNMGFQTLRQHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAVLQCGVPSPSVSNAYS---------------------------AGPESPHSAYSSDEGSYE-HLSSEEQELLDFTTWFDRYESGASMATKDWC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0M7F4-1", "uniprot_id": "A0ABK0M7F4_RAT", "id": "A0ABK0M7F4-1", "name": "", "aln": "-MEKC------------KSAGLLALH-----------------------------------------SPLRASPLGA------LARREPCRVSARQDTA-------DCARRRPCPSLPPG--------GVAEPAFLRQRNERERQRVRCVNEGYARLRQHLPRELAGQRLSKVETLRAAIGYIKQLQELLER------------------------------------------------HRPDLNSDGESKASSGASPCSSEPEERG-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QW46-1", "uniprot_id": "M0QW46_MOUSE", "id": "M0QW46-1", "name": "", "aln": "-MEKR------------RSAGLLALP-----------------------------------------SALRTAPLGA------LPGREPCRVSVRQDAA-------DCARRRPYSSLPLG--------GVAEPAFLRQRNERERQRVRCVNEGYARLRQHLPRELAGQRLSKVETLRAAISYIKQLQELLER------------------------------------------------HRPDCNSDGESKASSGASPCS-ESEERS-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XD76-1", "uniprot_id": "ASCL4_HUMAN", "id": "Q6XD76-1", "name": "Achaete-scute homolog 4", "aln": "-METR------------KPAERLALP-----------------------------------------YSLRTAPLGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQYLPVPLD--------SAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAG----------------------------------AVPQRRAECNSDGESKASSAPSPSS-EPEEGGS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NQ33-1", "uniprot_id": "ASCL3_HUMAN", "id": "Q9NQ33-1", "name": "Achaete-scute homolog 3", "aln": "MMDNRGNSSLPDKLPIFPDSARLPLTRSF------------------------------------YLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILG----NYSEPCPFS-FPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLY--PD---------------------------------------------KAETKNNPGKVSSMIATTSHHADPMFRIV----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJR7-1", "uniprot_id": "ASCL3_MOUSE", "id": "Q9JJR7-1", "name": "Achaete-scute homolog 3", "aln": "-MDTRSYPSPPDRLSVFAESAHLPLSRPF------------------------------------YLDPMVTVHLCPETPVPASYTDELPLLPFSSDTLIMN----NYGDPYPFP-FPMPYTNYRRCDYTYGPAFIRKRNERERQRVKCVNEGYARLRRHLPEDYLEKRLSKVETLRAAIKYISYLQSLLY--PD---------------------------------------------ESETKKNPRTAS------CGSLDPALRVI----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LUI6-1", "uniprot_id": "F1LUI6_RAT", "id": "F1LUI6-1", "name": "", "aln": "-MNSNFCRALVDR----GSPGGIQLG---------------------------------------VVAPAGPTPLAATEPLGN---VPFLLYPGHSEPSYYD----AYTGVFPYVPFPGAFGVY---DYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSAAPDGAPPTAT------------------------------SPPPAHAGHGNALQPPSLVAESS-GSSFSPSPFLESEEPSL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QWB7-1", "uniprot_id": "ASCL5_MOUSE", "id": "M0QWB7-1", "name": "Achaete-scute homolog 5", "aln": "-MNSNFCRALVDR----GPPGGMQLG---------------------------------------VVAPAGQTPLAATEPLSN---VPFLLYPGHSEPPYYD----AYTGVFPYVPFPGAFGVY---DYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALTEKRLSKVETLRAAIRYIKYLQELLSATPDGAPPPAT------------------------------SPPPAHTGHSNVPQPSSLVAESS-GSPFSSSPFLESEEPSL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU5-1", "uniprot_id": "ASCL5_HUMAN", "id": "Q7RTU5-1", "name": "Achaete-scute homolog 5", "aln": "-MNNNFCRALVDRR-PLGPPSCMQLG---------------------------------------VMPPPRQAPLPPAEPLGN---VPFLLYPGPAEPPYYD----AYAGVFPYVPFPGAFGVY---EYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPASRGLPGTGP----------------CPAPPATPRPDRPGDGEARAPSSLVPESSESSCFSPSPFLESEESWH------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10083-1", "uniprot_id": "AST5_DROME", "id": "P10083-1", "name": "Achaete-scute complex protein T5", "aln": "-MALGSENHSVFNDDEESSSAFNGPS----------------------------------------VIRRNARERNRVKQVNNGFSQLRQHIPAAVIADLSN------GRRGIGPGANKKLS-------KVSTLKMAVEYIRRLQKVLHENDQQKQKQLHLQQQHLHFQQQQQHQHLYAWHQELQLQSPTGSTSSCNSISSYCKPATSTIPG-------------------------ATPPNNFHTKLEASFEDYRNNSCSSGTEDEDILDYISLWQDDL-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *. ::* * : *: : .: . * ** . ", "identical_positions": 7, "similar_positions": 13, "identity": "2.41%" }, { "cls_id": "homologset.agr.FB:FBgn0000024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P37136-1", "uniprot_id": "ACES_RAT", "id": "P37136-1", "name": "Acetylcholinesterase", "aln": "----MRPPWYPLHTPSLASPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPG-GPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP-----------------------------YPRPTSPTP---VLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALPGSR------EAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPDALINTGDFQDLQVLVGVVKDEGSYFLVYGVPG-FSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPAHLRDAMSAVVGDHNVVCPVAQLAG------RLAAQG------------------------ARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTVEERIFAQRLMQYWTNFARTGDPNDPRD---SKSPRWPPYTTAAQQYVSLNLKP--LEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYS-KQERCSDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21836-1", "uniprot_id": "ACES_MOUSE", "id": "P21836-1", "name": "Acetylcholinesterase", "aln": "----MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPG-GPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP-----------------------------YPRPASPTP---VLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSR------EAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPG-FSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAG------RLAAQG------------------------ARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRD---SKSPQWPPYTTAAQQYVSLNLKP--LEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYS-KQERCSDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22303-1", "uniprot_id": "ACES_HUMAN", "id": "P22303-1", "name": "Acetylcholinesterase", "aln": "----MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPG-GPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP-----------------------------YPRPTSPTP---VLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSR------EAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPG-FSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAG------RLAAQG------------------------ARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRD---PKAPQWPPYTAGAQQYVSLDLRP--LEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYS-KQDRCSDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDE3-1", "uniprot_id": "ACES_DANRE", "id": "Q9DDE3-1", "name": "Acetylcholinesterase", "aln": "-----------MKTSDILLLPTVLLTFLFHN---CFAQAEPDLVVATRLGRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFSNACYQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPP----------------------------TPRPQNLT----VMVWIYGGGFYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSS------DAPGNVGLYDQRLALQWVQENIHFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTKLGKLVGCTWG----NDTELIDCLRNKHPQELIDQEWQVLPWSSLFRFSFVPVVDGVFFPDTPDAMISSGNFKYTQILLGVNQDEGSYFLLYGAPG-FSKDNESLISREDFLESVKMGVPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGAVYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRRRWPQFSANEQKHVGLNTEP--MKVHKGLRTQFCALWNRFLPRLLNITDNIDDVERQWKVEFHRWSSYMMHWKSQFDHYS-KQERCTDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8J8XQI9-1", "uniprot_id": "A0A8J8XQI9_RAT", "id": "A0A8J8XQI9-1", "name": "Carboxylic ester hydrolase", "aln": "----------MQTQHTMVTEIHFLLWILLLCMLFGKSHTEEDVIITTKTGRVRGLSMPILG-GTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDVYNATKYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIP-----------------------------VPKPKNAT----VMVWVYGGGFQTGTSSLPVYDGKFLTRVERVIVVSMNYRVGALGFLAFPGNS------EAPGNMGLFDQQLALQWIQRNIAAFGGNPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFIGCSKE----NEKEIITCLRSKDPQEILLNEKLVLPSDSIRSINFGPTVDGDFLTDMPHTLLQLGKVKTAQILVGVNKDEGTAFLVYGAPG-FSKDNDSLITRREFQEGLNMYFPGVSSLGKEAILFYYVDWLGDQTPEVYREAFDDIIGDYNIICPALEFTK------KFAELE------------------------INAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQG----NSTVWPVFTSTEQKYLTLNTEK--SKINSKLRAPQCQFWRLFFPKVLEITGDIDEREQEWKAGFHRWSNYMMDWKNQFNDYTSKKETCTDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03311-1", "uniprot_id": "CHLE_MOUSE", "id": "Q03311-1", "name": "Cholinesterase", "aln": "----------MQTQHTKVTQTHFLLWILLLCMPFGKSHTEEDFIITTKTGRVRGLSMPVLG-GTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDIHNATQYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIP-----------------------------VPKPKNAT----VMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNP------DAPGNMGLFDQQLALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFTGCSKE----NEMEMIKCLRSKDPQEILRNERFVLPSDSILSINFGPTVDGDFLTDMPHTLLQLGKVKKAQILVGVNKDEGTAFLVYGAPG-FSKDNDSLITRKEFQEGLNMYFPGVSRLGKEAVLFYYVDWLGEQSPEVYRDALDDVIGDYNIICPALEFTK------KFAELE------------------------NNAFFYFFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLGRRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQG----NSTMWPVFTSTEQKYLTLNTEK--SKIYSKLRAPQCQFWRLFFPKVLEMTGDIDETEQEWKAGFHRWSNYMMDWQNQFNDYTSKKESCTAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06276-1", "uniprot_id": "CHLE_HUMAN", "id": "P06276-1", "name": "Cholinesterase", "aln": "----------MHSKVTIIC-IRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFG-GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP-----------------------------APKPKNAT----VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNP------EAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRE----NETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPG-FSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTK------KFSEWG------------------------NNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQN----NSTSWPVFKSTEQKYLTLNTES--TRIMTKLRAQQCRFWTSFFPKVLEMTGNIDEAEWEWKAGFHRWNNYMMDWKNQFNDYTSKKESCVGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07140-1", "uniprot_id": "ACES_DROME", "id": "P07140-1", "name": "Acetylcholinesterase", "aln": "MAISCRQSRVLPMSLPLPLTIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQG-REVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWN--SYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEG-NPGYQNQQQIGRAVGDHFFTCPTNEYAQ------ALAERG------------------------ASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGE-------EWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAGTCDGDSG--SASISPRLQLLGIAALIYICAALRTKRVF--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: .:: . * ::* : . * .: ***:*:**: ** . . * .: :*. * * :*** * *:**** :******:*** * .* . * :::*:***** :*:::* :*:. :. . .::.*::****::*** : . :****:** ** **::*:: * ***:* :*:******::**. :::. : *. *.:::** * **: :* . * . .* * .:: *:*. .: : :: . . *.:** *:. * ::. ...: ::*:* :***: **:*. . *.**: : :.* .: :. . .. *:::: *..* : :: :. :** . ** . : : .. * * **:*. * **** ** ***:.** ** :* *. :.: :: :**: *.* ** :. : :. .: : * :* ::*:: . :. * . .. : . : : : : . ", "identical_positions": 146, "similar_positions": 181, "identity": "21.04%" }, { "cls_id": "homologset.agr.FB:FBgn0000028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTL1-1", "uniprot_id": "PO4F3_RAT", "id": "D3ZTL1-1", "name": "POU domain, class 4, transcription factor 3", "aln": "--MMAMNAKQ-PFGMHPV---LQEPKFSSLHSGS-------------------------------------------------------EAMRRVCLPAPQL----------------------------QGNIFGSFDESLLARAEALAAVDI-VSHGKNH--------PFKPDATYHTMSSVPCTS--TSPTVPISHP-AALTS--------HPHHPV-HQGLE-GDLLEHIS-PTLSVSG--------------------LGAP---------------------------EHSVMPAQIHP-HHLGAMGHLHQ---AMGMSHPHAVAPH----------------------------------SAMPACLSDVESDPRE-LEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKN---SKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAVH--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63955-1", "uniprot_id": "PO4F3_MOUSE", "id": "Q63955-1", "name": "POU domain, class 4, transcription factor 3", "aln": "--MMAMNAKQ-PFGMHPV---LQEPKFSSLHSGS-------------------------------------------------------EAMRRVCLPAPQL----------------------------QGNIFGSFDESLLARAEALAAVDI-VSHGKNH--------PFKPDATYHTMSSVPCTS--TSPTVPISHP-AALTS--------HPHHAV-HQGLE-GDLLEHIS-PTLSVSG--------------------LGAP---------------------------EHSVMPAQIHP-HHLGAMGHLHQ---AMGMSHPHAVAPH----------------------------------SAMPACLSDVESDPRE-LEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKN---SKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAVH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15319-1", "uniprot_id": "PO4F3_HUMAN", "id": "Q15319-1", "name": "POU domain, class 4, transcription factor 3", "aln": "--MMAMNSKQ-PFGMHPV---LQEPKFSSLHSGS-------------------------------------------------------EAMRRVCLPAPQL----------------------------QGNIFGSFDESLLARAEALAAVDI-VSHGKNH--------PFKPDATYHTMSSVPCTS--TSSTVPISHP-AALTS--------HPHHAV-HQGLE-GDLLEHIS-PTLSVSG--------------------LGAP---------------------------EHSVMPAQIHP-HHLGAMGHLHQ---AMGMSHPHTVAPH----------------------------------SAMPACLSDVESDPRE-LEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKN---SKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAVH--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90435-1", "uniprot_id": "PO4F3_DANRE", "id": "Q90435-1", "name": "POU domain, class 4, transcription factor 3", "aln": "--MMTMNGKQ-HFSMHP-----------ALHPSS-------------------------------------------------------EGMRRVCLPAPQL----------------------------QGNIFSGFDESLLARAEALAAADI-VSHGKSH--------PFKTDVTYHTMSSVPCTS--SSSTVPISHPSSNLPS--------HHHHHLSHQTLE-GDLLDHIS-SSLSVSG--------------------MGAPP--------------------------DPSVMTTQAHQ-HHL-QMGHLHQ---AMAMGHPHTLSVH----------------------------------NGM-ACVNDVESDPRE-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKN---GKPDLFNGNERKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAVH--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V7L5-1", "uniprot_id": "PO4F2_RAT", "id": "G3V7L5-1", "name": "POU domain, class 4, transcription factor 2", "aln": "MMMMSLNSKQ-AFSMPHAGSLHVEPKYSALHSASPGSSAPAAPSASSPSSSSNAGSGGGGGGGGGGGGGGRSSSSSSSGSGG-GGGGGSEAMRRACLPTP------------------------------PSNIFGGLDESLLARAEALAAVDI-VSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHP-SALAGTHHHHHHHHHHHHQPHQALE-GELLEHLS-PGLALGA--------------------MAGP---------------------------DGTVVSTPAHA-PHMATMNPMHQA--ALSMAHAHGLP-------------------------------------SHMGCMSDVDADPRD-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKL---TKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAGI--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63934-1", "uniprot_id": "PO4F2_MOUSE", "id": "Q63934-1", "name": "POU domain, class 4, transcription factor 2", "aln": "MMMMSLNSKQ-AFSMPHAGSLHVEPKYSALHSASPGSSAPAAPSASSPSSSSNAG--GGGGGGGGGGGGGRSSSSSSSGSGGSGGGGGSEAMRRACLPTP------------------------------PSNIFGGLDESLLARAEALAAVDI-VSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHP-SALAGTHHHHHHHHHHHHQPHQALE-GELLEHLS-PGLALGA--------------------MAGP---------------------------DGTVVSTPAHA-PHMATMNPMHQA--ALSMAHAHGLP-------------------------------------SHMGCMSDVDADPRD-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKL---TKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAGI--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12837-1", "uniprot_id": "PO4F2_HUMAN", "id": "Q12837-1", "name": "POU domain, class 4, transcription factor 2", "aln": "MMMMSLNSKQ-AFSMPHGGSLHVEPKYSALHSTSPGSSAPIAPSASSPSSSSNAG-GGGGGGGGGGGGGGRSSSSSSSGSSG---GGGSEAMRRACLPTP------------------------------PSNIFGGLDESLLARAEALAAVDI-VSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHP-SALAGTHHHHHHHHHHHHQPHQALE-GELLEHLS-PGLALGA--------------------MAGP---------------------------DGAVVSTPAHA-PHMATMNPMHQA--ALSMAHAHGLP-------------------------------------SHMGCMSDVDADPRD-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKL---TKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKYSAGI--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LC39-1", "uniprot_id": "A0ABK0LC39_RAT", "id": "A0ABK0LC39-1", "name": "POU domain protein", "aln": "--MMSMNSKQPHFAMHPT---LPEHKYPSLHSSS-------------------------------------------------------EAIRRACLPTPPL----------------------------QSNLFASLDETLLARAEALAAVDIAVSQGKSH--------PFKPDATYHTMNSVPCTS---TSTVPLAHH---------------HHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGAHDGPGGAGGPGGGGGPGGGGPGGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHGLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRE-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKM---NKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKFSATY--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17208-1", "uniprot_id": "PO4F1_MOUSE", "id": "P17208-1", "name": "POU domain, class 4, transcription factor 1", "aln": "--MMSMNSKQPHFAMHPT---LPEHKYPSLHSSS-------------------------------------------------------EAIRRACLPTPPL----------------------------QSNLFASLDETLLARAEALAAVDIAVSQGKSH--------PFKPDATYHTMNSVPCTS---TSTVPLAHH---------------HHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGAHDGPGGGGGPGGGGGPGGGGPGGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHGLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRE-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKM---NKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKFSATY--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01851-1", "uniprot_id": "PO4F1_HUMAN", "id": "Q01851-1", "name": "POU domain, class 4, transcription factor 1", "aln": "--MMSMNSKQPHFAMHPT---LPEHKYPSLHSSS-------------------------------------------------------EAIRRACLPTPPL----------------------------QSNLFASLDETLLARAEALAAVDIAVSQGKSH--------PFKPDATYHTMNSVPCTS---TSTVPLAHH---------------HHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGG-PGGGGGGG-PGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRE-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKM---NKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPR---------PSSEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRMKFSATY--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24350-2", "uniprot_id": "IPOU_DROME", "id": "P24350-2", "name": "Inhibitory POU protein", "aln": "-MTMSMYSTTDKMKMSAPS--CFPGRYSPSYRSS-------------------------------------------------------EQMRR-CMPNPSIHISSSCDSLESRLLEDASLLCNSWSARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHVHS------QMPSQIKHDVMYHHHSMS--GPPQRPLQEN---------------PFSRQMHHSMDQLDMLDPTG-SMTTLAP-------------------ISESP------------------------LTPTHQHLHGSYHSMNHMMSHHHPGTLSGHTGGHHGHSAVHHP----------------------------VITAAVAAAGLHPDTDTDPRE-LEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPR---------PSGEKIAAIAEKLDLKKNVVRVWFCNQR---QKQKRIVSSVTPSMTGHGSAGFGY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34161-1", "uniprot_id": "YOX1_YEAST", "id": "P34161-1", "name": "Homeobox protein YOX1", "aln": "--MSQETKMLPSLSSLLSGTEISSSPVSPSFTNP-----------------------------------------------------------RTSFHLDDR----------------------------GTIKLPPLNTSINRPRSVESALRHTVTSLHENSS------AYGDDMLKHTQSDSALSSQLNSSQETVDESHENLLLTP-----LNSKKRDYSVSSKKNDILTPLSAAKSIIIP--------------------SASKE--------------------------KRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQE---------------------------------LSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQRIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSS-SSPLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRVNKLINSIDHSPSKAKRPVSNPSGSPKRKRKFGFKIVDQQPLKDLDPNAFRG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . * .: : :: : .. :* : : .. * .. .: . . ::* . . : . . * : . . : .:: :** : . : : : *: . ::. : : * .*. : . : *.:.. :.. . .:. :* * :.. *** * ::*: ....:: : :.:* . . .: ..* :::::: . ", "identical_positions": 20, "similar_positions": 96, "identity": "3.54%" }, { "cls_id": "homologset.agr.FB:FBgn0000032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BZG2-1", "uniprot_id": "PPAT_HUMAN", "id": "Q9BZG2-1", "name": "Testicular acid phosphatase", "aln": "-----------MAGLGFWGHPAG---PLLLLLLLVLPPRAL-------------------PEGPLVFVALVFRHGDRAPLASYPMDPHKEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANLAGLFP--EAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWK-VLDTLMCQQAHGLPLPAWASPDVLRTLAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQR--LGLPLKMVMYSAHDSTLLALQGALGLYDGHTPPYAACLGFEFRKHLGNPAK-DGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRP------------------------------------------------GCLRALGGPV--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YTS9-1", "uniprot_id": "PPAT_MOUSE", "id": "D3YTS9-1", "name": "Testicular acid phosphatase", "aln": "-----------MAEPGSQGHTVG---PLLLLLLLLLP-RAL-------------------PEGPLLFVALVFRHGDRAPLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPEYKREEVYIRSTDFDRTLESAQANLAGLFP--EAAPGSPETDWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAADYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWK-VLDTLICQRAHGLDLPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRTQR--LGLPLKMVMYSAHDSTLLALQGALGLYDGNTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYRNDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPA-TVPLLAGAVAVLAVLSLGLGLLAWRP------------------------------------------------RCLRALGGTV--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GH32-1", "uniprot_id": "A0A8I6GH32_RAT", "id": "A0A8I6GH32-1", "name": "acid phosphatase", "aln": "-----------------MHHWRS---PVLCSVLRLET------------------------QG----TYMVFRHGDRAPLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPEYRREEVYIRSTDFDRTLESAQANLAGLFP--EAAPGSPEADWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAADYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWK-VLDTLICQRAHGLALPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRAQR--LGLPLKMVMYSAHDSTLLALQGALGLYDGNTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYRNDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPDRWSILWKQAKGGQVRLCLTCPGPSSSPRFYPRRDRIKQHTPQRAMIQPFNRNSRRQKFQGCPPHPSTKSRSTLARGHLCSQGDQTQLEGASRGKGMVKRKWGQGPQSKVFTKGGSPPHKKVSHKLKIKYKVKMLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20611-1", "uniprot_id": "PPAL_RAT", "id": "P20611-1", "name": "Lysosomal acid phosphatase", "aln": "-----------MAGRQSGWSQAA--LLQFLLGMCLMVMPPI-------------------QARSLRFVTLLYRHGDRSPVKAYPKDPYQEEK---WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNASYHRQEVYVRSTDFDRTLMSAEANLAGLFPPTEVQHFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNMSIQNAQFLDMVANETGLMNL--TLETIWN-VYDTLFCEQTHGLLLPPWASPQTVQRLSQLKDFSFLFLFGIHDQVQKARLQGGVLLAQILKNLTLMAT--TSQFPKLLVYSAHDTTLVALQMALNVYNGKQAPYASCHIFELYQE-------DNGNFSVEMYFRNDSKKAPWPLTLPGCPHRCPLQDFLRLTEPVIPKDWQKECQLASDTADTEVIVALAVCGSILFLLIVLLLTVLFRMQA-------------------------------------------QPPGYHHVADREDHA--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24638-1", "uniprot_id": "PPAL_MOUSE", "id": "P24638-1", "name": "Lysosomal acid phosphatase", "aln": "-----------MAGRQTGWSQAA--LLQFLLGMCLTVMPPI-------------------QARSLRFVTLLYRHGDRSPVKTYPKDPYQEEK---WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNEVQHFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNRSIQNAQFLNMVANETGLTNV--TLETIWN-VYDTLFCEQTHGLLLPPWASPQTVQRLSQLKDFSFLFLFGIHEQVQKARLQGGVLLAQILKNLTLMAT--TSQFPKLLVYSAHDTTLVALQMALNVYNGKQAPYASCHIFELYQE-------DNGNFSVEMYFRNDSKKAPWPLILPGCPHRCPLQDFLRLTEPVIPKDWQKECQLANDTADTEVIVALAVCGSILFLLIVLLLTILFRMQA-------------------------------------------QPPGYHHVADREDHA--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11117-1", "uniprot_id": "PPAL_HUMAN", "id": "P11117-1", "name": "Lysosomal acid phosphatase", "aln": "-----------MAGKRSGWSRAA--LLQLLLGVNLVVMPPT-------------------RARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE---WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDL--TLETVWN-VYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMAT--TSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQE-------DSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQA-------------------------------------------QPPGYRHVADGEDHA--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20646-1", "uniprot_id": "PPAP_RAT", "id": "P20646-1", "name": "Prostatic acid phosphatase", "aln": "-----------MRAVPLHLVGTASLTLGFLLLLSLRLD-PG-------------------QAKELKFVTLVFRHGDRGPIETFPNDPIKESS---WPQGFGQLTKWGMGQHYELGSYIRRRYGRFLNNSYKHDQVYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWQPIPVHTVSLSEDRLLYLPFRDCPRFQELKSETLKSEEFLKRLQPYKSFIDTLPSLSGFEDQ--DLFEIWSRLYDPLYCESVHNFTLPTWATEDAMTKLKELSELSLLSLYGIHKQKEKSRLQGGVLVNEILKNMKLATQ--PQKARKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHIMELYQ--------DNGGHFVEMYYRNETQNEPYPLTLPGCTHSCPLEKFAELLDPVIPQDWATECMGTSNHQASL----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CE08-1", "uniprot_id": "PPAP_MOUSE", "id": "Q8CE08-1", "name": "Prostatic acid phosphatase", "aln": "-----------MRAVPLPLSRTASLSLGFLLLLSLCLD-PG-------------------QAKELKFVTLVFRHGDRGPIETFPTDPITESS---WPQGFGQLTQWGMEQHYELGSYIRKRYGRFLNDTYKHDQIYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWQPIPVHTVSLSEDRLLYLPFRDCPRFEELKSETLESEEFLKRLHPYKSFLDTLSSLSGFDDQ--DLFGIWSKVYDPLFCESVHNFTLPSWATEDAMIKLKELSELSLLSLYGIHKQKEKSRLQGGVLVNEILKNMKLATQ--PQKYKKLVMYSAHDTTVSGLQMALDVYNGVLPPYASCHMMELYH--------DKGGHFVEMYYRNETQNEPYPLTLPGCTHSCPLEKFAELLDPVISQDWATECMATSSHQGRN----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15309-1", "uniprot_id": "PPAP_HUMAN", "id": "P15309-1", "name": "Prostatic acid phosphatase", "aln": "-----------MRAAPLLLARAASLSLGFLFLLFFWLDRSV-------------------LAKELKFVTLVFRHGDRSPIDTFPTDPIKESS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQ--DLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQ--IPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYF--------EKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I0P9-1", "uniprot_id": "Q8I0P9_DROME", "id": "Q8I0P9-1", "name": "acid phosphatase", "aln": "MFSRSRCGSLVTSVARKMWNHPSQRWLILICVICLLSFALANSLHGYANAEGHPVEISATLPGQLKFVHVIYRHGDRTPVDPYPTDPWGDRK--FWPTGWGDLTNLGKQEHYDLGKWLRNRYSNLLPPIYSNENIYVQSTDVDRTLMSAQSNLAGLYEPQGEDIWNTDINWQPIPIHTSPEREDPILAAKAP-CPAYDYELASLESSPEFKALTEKHRNLFAYLSEKGGRPVKTFIDAQYLN---NTLFIENLYNMTLPKWT--KMVYGREELTYVSNFAFAISSYTRKLARLKAGPLLKDIFQRFKEKSSGSLKPDRSMWVYSAHDTTVASVLNALKLFELHSPPYTACIMMELRVD-------ETNTPLVSIFYKN-TTAEPLPLDIPGCGPSCPLTKLMNIYEDVLPVDWERECKLSTMMMTYEEANLGTATGILILIVIALLFASYGLMIYYR------------------------------------------RRNYKLYSSYSQMA--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . :::***** *: .:* ** : ** * *:** * :: :** :* ** :* * .:::*::***.**** ** :***.*: .. *:***:** . ** :* ** :. . .: :: :: : . * . :.* : :.: ** *: . : .:. .. : ::* .* *: * .:. .: :*****:*: .: ** ::: .**::* *: : *.: ::* : * ** :*** *** : .: . . * . ", "identical_positions": 81, "similar_positions": 95, "identity": "14.39%" }, { "cls_id": "homologset.agr.FB:FBgn0000036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09483-1", "uniprot_id": "ACHA4_RAT", "id": "P09483-1", "name": "Neuronal acetylcholine receptor subunit alpha-4", "aln": "--------------------------------------MANSGTGAPPPLLLLPLLLLLGTG--------------------LLPASSHIETRAHAEERLLKRLFSG--YNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGD----YENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMHSRVD------------QLDFWESGEWVIVDAVG---TYNTRKYECCAEIYPDITYAFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKVTLCISVLLSLTVFLLLITEIIPSPTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHT-MPAWVRRVFLDIVPRLLFMKRPSVVKDNCRRLIESMHKMANAPRFWPEPVGEPGILSDICNQGLSP-APTFCNPTDTAVETQPTCRSPPLEVPDLKTSEVEKASPCPSPGSCPPPKSSSGAPMLIKARSLSVQHVPSSQEAAEDGIRCRSRSIQYCVSQ-DGAASLADSKPTSSPTSLKARPSQLPVSDQASPCKCTCK-EPSPVSPVTVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAAC----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70174-1", "uniprot_id": "ACHA4_MOUSE", "id": "O70174-1", "name": "Neuronal acetylcholine receptor subunit alpha-4", "aln": "--------------------------------------MEIGGSGAPPPLLLLPLLLLLGTG--------------------LLPASSHIETRAHAEERLLKRLFSG--YNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGD----YENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMHSRVD------------QLDFWESGEWVIVDAVG---TYNTRKYECCAEIYPDITYAFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKVTLCISVLLSLTVFLLLITEIIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHT-MPAWVRRVFLDIVPRLLFMKRPSVVKDNCRRLIESMHKMANAPRFWPEPESEPGILGDICNQGLSP-APTFCNRMDTAVETQPTCRSPSHKVPDLKTSEVEKASPCPSPGSCHPP-NSSGAPVLIKARSLSVQHVPSSQEAAEGSIRCRSRSIQYCVSQ-DGAASLTESKPTGSPASLKTRPSQLPVSDQTSPCKCTCK-EPSPVSPITVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43681-1", "uniprot_id": "ACHA4_HUMAN", "id": "P43681-1", "name": "Neuronal acetylcholine receptor subunit alpha-4", "aln": "--------------------------------------MELGGPGAPR--LLPPLLLLLGTG--------------------LLRASSHVETRAHAEERLLKKLFSG--YNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPAD----YENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVD------------QLDFWESGEWVIVDAVG---TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHT-MPTWVRRVFLDIVPRLLLMKRPSVVKDNCRRLIESMHKMASAPRFWPEPEGEP--PATSGTQSLHPPSPSFCVPLDVPAEPGPSCKSPSDQLPPQQPLEAEKASPHPSPGPCRPP-HGTQAPGLAKARSLSVQHMSSPGEAVEGGVRCRSRSIQYCVPR-DDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSVSPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12389-1", "uniprot_id": "ACHA2_RAT", "id": "P12389-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "--------------------------------------MTLSHSALQFWTHLYLWCLLLVPA-----------------------VLTQQGSHTHAEDRLFKHLFGG--YNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNVTSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERTVD------------LKDYWESGEWAIINATG---TYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRP---------------------------------------------------------------------LPPMELHGSPDLKLSP-----------------------SYHWLETNMDAGE-----REETEEEEEEE-DENICVCAGLPDSSMGVLYGHG---------------------GLHLRAMEPETKTPSQASEILLSPQIQKALEGVHYIADRLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X60-1", "uniprot_id": "ACHA2_MOUSE", "id": "Q91X60-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "--------------------------------------MAPSHPAFQFWIHLYLWCLLLMPA-----------------------VLAQQGSHTHAEDRLFKHLFGG--YNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERTVD------------LKDYWESGEWAIINATG---TYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRP---------------------------------------------------------------------LPPMELHGSPGLKLSP-----------------------TYHWLETNMDAEE-----REETEEEEEEEEDENICMCAGLPDSSMGVLYGHG---------------------SLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15822-1", "uniprot_id": "ACHA2_HUMAN", "id": "Q15822-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "--------------------------------------MGPSCPVFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDRLFKHLFRG--YNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTD----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVD------------LKDYWESGEWAIVNATG---TYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG-EKITLCISVLLSLTVFLLLITEIIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHT-MPHWVRGALLGCVPRWLLMNRP---------------------------------------------------------------------PPPVELCHPLRLKLSP-----------------------SYHWLESNVDAEE-----REVVVEE------EDRWACAGHVAPSVGTLCSHG---------------------HLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLPPFLAGMI---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43143-1", "uniprot_id": "ACHA6_RAT", "id": "P43143-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "---------------------------------------MLNGWGR--GDLRSGLCLWICG----------------------FLAFFKGSRGCVSEEQLFHTLFAH--YNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTE----YDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVD------------MNDFWENSEWEIVDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPS-TSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHT-MPKWVKTMFLQVFPSILMMRRP--------------------------------------------------------------------------LDKTKEMDGVK----------------------DPK--THTKRP------------AKVKFTHRKEPKLLKECRHCHKSSEIAPGK--------------------------RLS-QQPAQWVTENSEHPPDVEDVIDSVQFIAENMKSHNETKEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQPLLGNTGAS-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0W9-1", "uniprot_id": "ACHA6_MOUSE", "id": "Q9R0W9-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "---------------------------------------MLNSRDQ--GNLHSGLCLWLCG----------------------FLALFKGSTGCESEEQLFHRLFAH--YNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTE----YDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVD------------MNDFWENSEWEIVDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPS-TSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHT-MPKWVKTIFLQAFPSILMMRKP--------------------------------------------------------------------------LDKTKEAGGVK----------------------DPK--SHTKRP------------AKVKFTHRGESKLLKECHHCQKSSDIAPGK--------------------------RRSSQQPARWVAENSEHSSDVEDVIESVQFIAENMKSHNETNEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQPLLGNTGKS-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15825-1", "uniprot_id": "ACHA6_HUMAN", "id": "Q15825-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "---------------------------------------MLTSKGQ--GFLHGGLCLWLCV----------------------FTPFFKGCVGCATEERLFHKLFSH--YNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPME----YDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVD------------MNDFWENSEWEIIDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPS-TSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHT-MPRWVKTVFLKLLPQVLLMRWP--------------------------------------------------------------------------LDKTRGTGSDA----------------------VPR--GLARRP------------AKGKLASHGEPRHLKECFHCHKSNELATSK--------------------------RRLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGKS-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04757-1", "uniprot_id": "ACHA3_RAT", "id": "P04757-1", "name": "Neuronal acetylcholine receptor subunit alpha-3", "aln": "------------------------------------MGVVLL------PPPLSMLMLVL--------------------------MLLPAASASEAEHRLFQYLFED--YNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSD----YQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMN------------LKDYWESGEWAIIKAPG---YKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT-MPTWVKAVFLNLLPRVMFMTRPT--------------------------------------------------------------------SGEGDTPKTRTFYGAE----------------------LSNLNCFSRAD---------SKSCKEGYPCQDGTCGYCHHRRVKISNFSANLT--------------------------RSSSSESVNAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLMARDDT--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4G9-1", "uniprot_id": "ACHA3_MOUSE", "id": "Q8R4G9-1", "name": "Neuronal acetylcholine receptor subunit alpha-3", "aln": "------------------------------------MGVVLP------PPPLSMLMLVL--------------------------MLLPVASASEAEHRLFQYLFED--YNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSD----YQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMN------------LKDYWESGEWAIIKAPG---YKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT-MPTWVKAVFLNLLPRVMFMTRPT--------------------------------------------------------------------STEEDAPKTRNFYGAE----------------------LSNLNCFSRAD---------SKSCKEGYPCQDGTCGYCHHRRVKISNFSANLT--------------------------RSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLMARDDT--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HV46-1", "uniprot_id": "A0AC58HV46_DANRE", "id": "A0AC58HV46-1", "name": "", "aln": "MRSLSDQYLHWKQDENSCIFCSLSLTHTYMRTHTHTLSLSLSSSSSPGPPLVCTAALFLSPDCTMNTGALLIFFS----SFSPLCFLLSGVCCSEAEHRLFSVIFSS--YNQYIRPVENVSDPVVVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKD----FGGVEFIRVPSNKIWKPDIVLYNNAVGDFQVDDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGSTIN------------LKDFWESGEWTIIDAPG---YKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPS-TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHT-MPCWVRRVFLSLLPRVMFMTRPE--------------------------------------------------------------------KDQEVPAKQCSVHPPV----------------------SSKQTSVCRGPQLLLCPTELNEASRTAFLCREHHCWKKHISNMTSEGAEDGGS--------------------------PCSSSESLDGFLCMSAVSPQVREAIESVKYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLLGEDM--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12391-1", "uniprot_id": "ACHB3_RAT", "id": "P12391-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "------------------------------------------------MTGFLRVFLVLS--------------ATLSGSWVTLTATAGLSSVAEHEDALLRHLFQG--YQKWVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEE----YGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVD------------RKDFFDNGEWEILNAKG---MKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPS-SSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQRLPRWLCMKDPM-------------------------------------------------------------------------------------------------------------------------------------------DRFSFPDGKESDTAVRGKVS----------------------------GKRKQTPASDGERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIASVLGSILIFIPALKMWIHRFH------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMN3-1", "uniprot_id": "ACHB3_MOUSE", "id": "Q8BMN3-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "------------------------------------------------MTGFLRVFLALS--------------ATLSGSWVTLTATAGLSSVAEHEDALLRHLFQG--YQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPED----YGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTYDGTMVDLILINENVD------------RKDFFDNGEWEILNAKG---MKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPS-SSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCMKDPR-------------------------------------------------------------------------------------------------------------------------------------------DRFSFPDGTESKGTVRGKFP----------------------------GKKKQTPTSDGERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTASVLGSVLIFIPALKMWIHRFH------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05901-1", "uniprot_id": "ACHB3_HUMAN", "id": "Q05901-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "-----------------------------------------------MLPDFMLVLIVLG--------------IPSS-------ATTGFNSIAENEDALLRHLFQG--YQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDD----YGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVD------------RKDFFDNGEWEILNAKG---MKGNRRDGVYS--YPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPS-SSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMKDHV-------------------------------------------------------------------------------------------------------------------------------------------DRYSSPEKEESQPVVKGKVL----------------------------EKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20420-1", "uniprot_id": "ACHA5_RAT", "id": "P20420-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "-----------------------------------------------------MVQLLAGRW------------RPTGARRGTRGGLPELSSAAKHEDSLFRDLFED--YERWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVD------------RTDFFDNGEWEIMSAMG---SKGNRTDSCCW--YPYITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPS-SSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHA-------------------------------------------------------------------------------------------------------------------------------------------DRYFT--------------------------------------------QREEAESGAGPKS-RNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2MKA5-1", "uniprot_id": "ACHA5_MOUSE", "id": "Q2MKA5-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "--------------------------------------MAARGSRRRALRLLLMVQLLAGRW------------RPAGAARGARGGLPELSSAAKHEDSLFRDLFED--YEKWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVD------------RTDFFDNGEWEIMSAMG---SKGNRTDSCCW--YPCITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPS-SSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHA-------------------------------------------------------------------------------------------------------------------------------------------DRYFT--------------------------------------------QREEAEKDGGPKS-RNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30532-1", "uniprot_id": "ACHA5_HUMAN", "id": "P30532-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "--------------------------------------MAARGSGPRALRLLLLVQLVAGRC------------GLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQD--YERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKVIRVPSDSVWTPDIVLFDNADGRFEG-TSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVD------------KRDFFDNGEWEIVSATG---SKGNRTDSCCW--YPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEG-EKICLCTSVLVSLTVFLLVIEEIIPS-SSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMRSHV-------------------------------------------------------------------------------------------------------------------------------------------DRYFT--------------------------------------------QKEETESGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPVIYKWANILIPVHIGNANK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09478-1", "uniprot_id": "ACH1_DROME", "id": "P09478-1", "name": "Acetylcholine receptor subunit alpha-like 1", "aln": "----------------------------------------------MGSVLFAAVFIALH--------------------------FATGGLANPDAKRLYDDLLSN--YNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDD----YGGVDTLHVPSEHIWLPDIVLYNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADS---DNIEVGIDLQDYYISVEWDIMRVPA---VRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSG-EKISLCISILLSLTVFFLLLAEIIPP-TSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHR-MAPWVQRLFIQILPKLLCIERPKK-------------------------------------------------------------EEPEEDQPPEVLTDVYHLPPDVDKFVNYDSKRFSGDYGIPALPASHRFDLAAAGGISAHCFAEPPLPSSLPLPGADDDLFSPSGLNGDISPGCCPAA---------------------------AAAAAADLSPTFEKPYAREMEKTIEGSRFIAQHVKNKDKFESVEEDWKYVAMVLDRMFLWIFAIACVVGTALIILQAPSLYDQSQPIDILYSKIAKKKFELLKMGSENTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17787-1", "uniprot_id": "ACHB2_HUMAN", "id": "P17787-1", "name": "Neuronal acetylcholine receptor subunit beta-2", "aln": "-----------------------------------------------MARRCGPVALLLGFG---------------------LLRLCSGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEE----FDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVAS------------LDDFTPSGEWDIVALPG---RRNENPD---DSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG-EKMTLCISVLLALTVFLLLISKIVPP-TSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHT-MAPWVKVVFLEKLPALLFMQQPR------------------------------------------------------------------------HHCARQRLRLRR------------------------RQREREGAG------------ALFFREAPGADSCTCFVNRASVQGLAGAFG---------------------------AEPAPVAGPGRSGEPCGCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTTTTFLHSDHSAPSSK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11230-1", "uniprot_id": "ACHB_HUMAN", "id": "P11230-1", "name": "Acetylcholine receptor subunit beta", "aln": "----------------------------------------------MTPGALLMLLGALGAP------------------------LAPGVRGSEAEGRLREKLFSG--YDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQ---GHQEIHIHEGTFIENGQWEIIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPE-TSLSVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQ-MPLWVRQIFIHKLPLYLRLK----------------------------------------------------------------------------RPKPERD------------------------------LMPEPPHCSSPGSGWGRGTDEYFIRKPPSDFLFPKPNRFQPELSAPDLRRFID-------------------------------GPNRAVALLPELREVVSSISYIARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIIFTSVGTLVIFLDATYHLPPPDPFP----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09690-1", "uniprot_id": "ACHB_MOUSE", "id": "P09690-1", "name": "Acetylcholine receptor subunit beta", "aln": "----------------------------------------------MALGALLLLLGVLGTP------------------------LAPGARGSEAEGQLIKKLFSN--YDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGE---ERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPE-TSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQ-MPFWVRQIFIHKLPPYLGLK----------------------------------------------------------------------------RPKPERD------------------------------QLPEPHHSLSPRSGWGRGTDEYFIRKPPSDFLFPKLNRFQPESSAPDLRRFID-------------------------------GPTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F9V1-1", "uniprot_id": "E7F9V1_DANRE", "id": "E7F9V1-1", "name": "", "aln": "--------------------------------------------MDQNLSSKIIWL-WILLF------------------------RFSGALC-NLEGSLHRDLMVG--YNKNIRPVESHEDIIDVKIKMTLTNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLENNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLS-DEDNV---TMEWIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELE--HQEIIFFLIIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPE-TSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHP-MSNTIRKVLLNILPRVLRMTMQRW------------------------------------------------------------------------TPEQEEGDFKM----------------------FALGNGTPLRRRRRSSLGLIAKADEYMFRTARSELMFSRL-KERKGLLKNTLEKIQNG----------------------LGGNTAQDLECSLAAASPEVQQCVSSCKHIAESTKHQNDFQSKNEEWFLVARVIDRMCFFVMALLFILGTIGIFLTGHFNQAPSQPFPGDPKKYLPEISAGDIPG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20782-1", "uniprot_id": "ACHE_MOUSE", "id": "P20782-1", "name": "Acetylcholine receptor subunit epsilon", "aln": "------------------------------------------------MAGALLGA-LLLLT------------------------LFGRSQGKNEELSLYHHLFDN--YDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIDWHDYRLNYSKDD----FAGVGILRVPSEHVWLPEIVLENNIDGQFGVAYDSNVLVYEGGYVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFIFAVDDDGN---TINKIDIDTAAFTENGEWAIDYCPGMIRRYEGGSTEGPG--ETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPE-TSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHA-TSPRLRQILLELLPRLLGS-----------------------------------------------------------------------------SPPPED-------------------------------PRTASPARRASSVGILLRAEELILKKPRSELVFEGQ-RHRHGTWTAALC--QN-----------------------------------LGAAAPEIRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYP-------PCIQP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07001-1", "uniprot_id": "ACHD_HUMAN", "id": "Q07001-1", "name": "Acetylcholine receptor subunit delta", "aln": "------------------------------------------------MEGPVLTLGLLAAL------------------------AVCGSWGLNEEERLIRHLFQEKGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEE----FGNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEIVHRPARVNVDPRAPLDSPS--RQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPADSG-EKTSVAISVLLAQSVFLLLISKRLPA-TSMAIPLIGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHV-LSEGVKKLFLETLPELLHM-----------------------------------------------------------------------------SRPAEDG------------------------------PSPGALVRRSSSLGYISKAEEYFLLKSRSDLMFEKQ-SERHGLARRLTTARRP----------------------------PASSEQAQQELFNELKPAVDGANFIVNHMRDQNNYNEEKDSWNRVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPPQPFPGDP--YSYNVQDKRFI------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: *: **. . : : . : :::* .:. :: : * ::: * * :* : . .: :::... :* *:: * :* * : .. : * : * *. ::* * :.: .**** *.* : * * .* : : : . :* * . : : : ::* .:** : :: **: :: : ..::**.. * :* : *: :**:::: . :* :* :*:: .:*:* * ..*: :: : .:*: *:. *: . :: :: .* : : . .: .. ..* :. .:*.: :: *: :: ", "identical_positions": 56, "similar_positions": 132, "identity": "7.55%" }, { "cls_id": "homologset.agr.FB:FBgn0000037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08485-1", "uniprot_id": "ACM4_RAT", "id": "P08485-1", "name": "Muscarinic acetylcholine receptor M4", "aln": "--------------------------------MXNFTPVNGSSA-------------------NQSVRLVT----------------------AAHNHLETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLGCADLIIGAFSMNLYTLYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLS-NPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKE--------------------------------------------------------------------------------------------------------------------------------------------------KKAKTLAFLKSPLMKPSIKKPPPG-----GASREELRNGKLEEAPPPALPPPPRPVPDKDTSNESSSGSATQNTKERPPTE--------------------------------------------------------------------------------------LSTAEA-TTPALPAPTLQPRTLNPASKWS-----KIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAAR-ERKVTRTIFAILLAFILTWTPYNVMVLVN--TFCQSCIPERVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32211-1", "uniprot_id": "ACM4_MOUSE", "id": "P32211-1", "name": "Muscarinic acetylcholine receptor M4", "aln": "--------------------------------MANFTPVNGSSA-------------------NQSVRLVT----------------------TAHNHLETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTLYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLS-NPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKE--------------------------------------------------------------------------------------------------------------------------------------------------KKAKTLAFLKSPLMKPSIKKPPPG-----GASREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPPTE--------------------------------------------------------------------------------------LSTTEAATTPALPAPTLQPRTLNPASKWS-----KIQIVTKQTGSECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAAR-ERKVTRTIFAILLAFILTWTPYNVMVLVN--TFCQSCIPERVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08173-1", "uniprot_id": "ACM4_HUMAN", "id": "P08173-1", "name": "Muscarinic acetylcholine receptor M4", "aln": "--------------------------------MANFTPVNGSSG-------------------NQSVRLVTS---------------------SSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLS-NPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKE--------------------------------------------------------------------------------------------------------------------------------------------------KKAKTLAFLKSPLMKQSVKKPPPG-----EAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATE--------------------------------------------------------------------------------------LSTTEA-TTPAMPAPPLQPRALNPASRWS-----KIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAAR-ERKVTRTIFAILLAFILTWTPYNVMVLVN--TFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10980-1", "uniprot_id": "ACM2_RAT", "id": "P10980-1", "name": "Muscarinic acetylcholine receptor M2", "aln": "--------------------------------------MNNSTN-------------------SSNNGLAI------------------------TSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVAN--------------------------------------------------------------------------------------------------------------------------------------------------QDPVSPSLVQGRIVKPNNNNMPGGD---GGLEHNKIQNGK---APRDGVTENCVQGEEKESSNDSTSVSAVAS-NMRDDE---------------------------------------------------------------------------------------ITQDENTVSTSL-GHSRDDNSKQTCIKIV-----TKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPA-KKKPPPSR-EKKVTRTILAILLAFIITWAPYNVMVLIN--TFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERZ4-1", "uniprot_id": "ACM2_MOUSE", "id": "Q9ERZ4-1", "name": "Muscarinic acetylcholine receptor M2", "aln": "--------------------------------------MNNSTN-------------------SSNNGLAI------------------------TSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVAN--------------------------------------------------------------------------------------------------------------------------------------------------QDPVSPSLVQGRIVKPNNNNMPGGD---GGLEHNKIQNGK---APRDGGTENCVQGEEKESSNDSTSVSAVAS-NMRDDE---------------------------------------------------------------------------------------ITQDENTVSTSL-GHSKDDNSRQTCIKIV-----TKTQKGDACTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPA-KKKPPPSR-EKKVTRTILAILLAFIITWAPYNVMVLIN--TFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08172-1", "uniprot_id": "ACM2_HUMAN", "id": "P08172-1", "name": "Muscarinic acetylcholine receptor M2", "aln": "--------------------------------------MNNSTN-------------------SSNNSLAL------------------------TSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFS-NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVAN--------------------------------------------------------------------------------------------------------------------------------------------------QDPVSPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGK---APRDPVTENCVQGEEKESSNDSTSVSAVAS-NMRDDE---------------------------------------------------------------------------------------ITQDENTVSTSL-GHSKDENSKQTCIRIG-----TKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA-KKKPPPSR-EKKVTRTILAILLAFIITWAPYNVMVLIN--TFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TCF0-1", "uniprot_id": "A0AB32TCF0_DANRE", "id": "A0AB32TCF0-1", "name": "Muscarinic acetylcholine receptor", "aln": "------------------------------METFNLTLSPSSSH-------------------ANKTNIFQ------------------------DGPFKPVEFVLIVLGLSILSLITIIGNVLVMLSIKVNRNLQTVNNYFLFSLACADLFIGVFSMNLYTVYIVTGHWPLGALVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVKRTHKMAGMMIAAAWILSFILWAPAILFWQFITGSRTVPEGECYIQFFS-NAVVTFGTAIAAFYLPVITMTILYWQISKASRSRVRRRDNRRVS--------------------------------------------------------------------------------------------------------------------------------------------------------------RVSNDGGQAGLGNE---RNMDRKSTQEGEEM-VSRKQSASDTTTGEERDSENDSISGSVLASSNQRDDEA--------------------------------------------------------------------------------------VSISTNGDIRAR-QNQSASLATESWVRFT-----CFKTASQKDLQNTYKVNSESQGMTNGKERLSLVSQKIISPHSQ---KRKSSSSR-EKKVTRTIMAILVAFATTWTPYNVMVLIN--TFCSDCIPNTVWIFGYWLCYINSTVNPACYALCNVTFKNTFKQLLTCKYRNIHATRKQ------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08482-1", "uniprot_id": "ACM1_RAT", "id": "P08482-1", "name": "Muscarinic acetylcholine receptor M1", "aln": "----------------------------------MNTSVPPAVS-------------------PNITVLAP--------------------------GKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLS-QPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSE-------------------------------------------------------------------------------------------------------------------------------------------------TPGKGGGSSSSSERSQPGAEGSPES---PPGRCCRC--------CRAPRLLQAYSWKE--EEEEDEGSMESLTSSEGEEPG-----------------------------------SEVVIKMP--------------------------------------------MVDSEAQAPTKQPPKSSPN---------------TVKRPTKKGRDRGGKGQKP-------------------RGKEQLAKRKTFSLVK-EKKAARTLSAILLAFILTWTPYNIMVLVS--TFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGS---VHRTPSRQC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12657-1", "uniprot_id": "ACM1_MOUSE", "id": "P12657-1", "name": "Muscarinic acetylcholine receptor M1", "aln": "----------------------------------MNTSVPPAVS-------------------PNITVLAP--------------------------GKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLS-QPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSE-------------------------------------------------------------------------------------------------------------------------------------------------TPGKGGGSSSSSERSQPGAEGSPES---PPGRCCRC--------CRAPRLLQAYSWKE--EEEEDEGSMESLTSSEGEEPG-----------------------------------SEVVIKMP--------------------------------------------MVDPEAQAPTKQPPKSSPN---------------TVKRPTKKGRDRGGKGQKP-------------------RGKEQLAKRKTFSLVK-EKKAARTLSAILLAFILTWTPYNIMVLVS--TFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGS---VHRTPSRQC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11229-1", "uniprot_id": "ACM1_HUMAN", "id": "P11229-1", "name": "Muscarinic acetylcholine receptor M1", "aln": "----------------------------------MNTSAPPAVS-------------------PNITVLAP--------------------------GKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLS-QPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSE-------------------------------------------------------------------------------------------------------------------------------------------------TPGKGGGSSSSSERSQPGAEGSPET---PPGRCCRC--------CRAPRLLQAYSWKE--EEEEDEGSMESLTSSEGEEPG-----------------------------------SEVVIKMP--------------------------------------------MVDPEAQAPTKQPPRSSPN---------------TVKRPTKKGRDRAGKGQKP-------------------RGKEQLAKRKTFSLVK-EKKAARTLSAILLAFILTWTPYNIMVLVS--TFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGS---VHRTPSRQC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08483-1", "uniprot_id": "ACM3_RAT", "id": "P08483-1", "name": "Muscarinic acetylcholine receptor M3", "aln": "------------------------------MTLHSNSTTSPLFP--NISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSND-----TSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASG----------------------------------------------------------------------------------------------------------------------------------------TEAEAENFVHPTGSSRSCSSYELQQQGVKRSSRR---KYGRCHFW-FTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIG-----------------------------SETRAIYSIVLKLPGHSSILNST-------------------KLPSSDNLQVSNEDLGTVDVERNAHKLQAQKSMGDGDNCQKDFTKLPIQLESAVDTGKTSDTNSSADKTTATLPLSFKEATLAKRFALKTRSQITKRKRMSLIK-EKKAAQTLSAILLAFIITWTPYNIMVLVN--TFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKTLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERZ3-1", "uniprot_id": "ACM3_MOUSE", "id": "Q9ERZ3-1", "name": "Muscarinic acetylcholine receptor M3", "aln": "------------------------------MTLHSNSTTSPLFP--NISSSWVHSPSEAGLPLGTVSQLDSYNISQTSGNFSSND-----TSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASG----------------------------------------------------------------------------------------------------------------------------------------TEAEAENFVHPTGSSRSCSSYELQQQGTKRSSRR---KYGGCHFW-FTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIG-----------------------------SETRAIYSIVLKLPGHSTILNST-------------------KLPSSDNLQVPDKDLGTMDVERNAHKLQAQKSMDDRDNCQKDFSKLPIQLESAVDTAKTSDTNSSVDKTTAALPLSFKEATLAKRFALKTRSQITKRKRMSLIK-EKKAAQTLSAILLAFIITWTPYNIMVLVN--TFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20309-1", "uniprot_id": "ACM3_HUMAN", "id": "P20309-1", "name": "Muscarinic acetylcholine receptor M3", "aln": "------------------------------MTLHNNSTTSPLFP--NISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDG----TTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLS-EPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASG----------------------------------------------------------------------------------------------------------------------------------------TEAETENFVHPTGSSRSCSSYELQQQSMKRSNRR---KYGRCHFW-FTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIG-----------------------------SETRAIYSIVLKLPGHSTILNST-------------------KLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVK-EKKAAQTLSAILLAFIITWTPYNIMVLVN--TFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNY8-1", "uniprot_id": "A0A8M9PNY8_DANRE", "id": "A0A8M9PNY8-1", "name": "Muscarinic acetylcholine receptor", "aln": "--------------------------------MDSNSTELGHFSPSDTLGVGMYPASTLWPLLQNTSLVNLTAVFKLNGSNAEAEG----QSYDPLGGHSLWQVILIVVFTGLLSLITIIGNILVMVSFKVNRQLKTVNNYFLLSLAVADLIIGVISMNLYTAYIVMGQWAMGNWACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWFVSLILWAPAILFWQYFVGQRTVPQDKCYIQFLS-EPIITFCTAMAAFYLPVTIMSVLYWRIYKETENRSRELAGLQGSGGRFGG-----------------------------------------------------------------------------------------------------------------------------------VERPRFHLHATRGSSRSCSSFELGQPGHKKASVHS--LSGRFHCWGWKSGGSDKSGPNREADQSSSDSWNNNDAGLSADHSGSSDEDESAP----------------------------STTRAIFSIVLSLPGVRAAVNS--------------------QVTSCEELDTEEDPLRSAEEKDSRDGSISRSVTNGNKRFVGGMSKVQSMSAIQPTTDTTTDSTNTTIKS-PSAPITFKEAALAKRFAARARTQITKRKRMSLIK-EKKAAQTLSAILFAFIITWTPYNIMVLVN--TFCNGCIPENLWALGYWLCYVNSTVNPMCYALCNKTFRSTFKMILLCRWDQKKS-KPSFPQRQAVRFHRPIPTDST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08911-1", "uniprot_id": "ACM5_RAT", "id": "P08911-1", "name": "Muscarinic acetylcholine receptor M5", "aln": "------------------------------MEGESYN-ESTVNG-----------------TPVNHQALER---------------------------HGLWEVITIAVVTAVVSLMTIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSD-------------------------------------------------------------------------------------------------------------------------------------------------SVAEAKKREPAQRTLLRSFFSCPRPSLAQRERNQASWSSSRRSTSTTGKTTQATDLSADWEKAEQVTTCSSYPSSEDEAKP------------------------------TTDPVFQMVYKSEAKESPGKES-------------------NTQETKETVVNTRTENSDYDTPKYFLSPAAAHRLKSQKCVAYKFR---LVVKADGTQETNNGCRKVKIMPCSFPVSKDPST--KGPDPNLSHQMTKRKRMVLVK-ERKAAQTLSAILLAFIITWTPYNIMVLVS--TFCDKCVPVTLWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKKKKVEEKLYWQGN-----SKLP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920H4-1", "uniprot_id": "ACM5_MOUSE", "id": "Q920H4-1", "name": "Muscarinic acetylcholine receptor M5", "aln": "------------------------------MEGESYHNETTVNG-----------------TPVNHQALER---------------------------HGLWEVITIAAVTAVVSLMTIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSD-------------------------------------------------------------------------------------------------------------------------------------------------SVAEVKKRKPAHRTLLRSFFSCPRPSLAQRVRNQASWSSSRRSTSTTGKPTQATDLSADWEKAEQVTNCSSCPSSEDEAKA------------------------------TTDPVFQVVCKNEAKESPGKEF-------------------NTQETKETFVSPRTENNDYDTPKYFLSPGAAHRLKSQKCVAYKFR---LVVKADGTQETNNGCRKVKIMPCSFPVSKDPST--KGLDPHLSHQMTKRKRMVLVK-ERKAAQTLSAILLAFIITWTPYNIMVLVS--TFCDKCVPVTLWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKKKKVEEKLYWQGN-----SKLP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08912-1", "uniprot_id": "ACM5_HUMAN", "id": "P08912-1", "name": "Muscarinic acetylcholine receptor M5", "aln": "------------------------------MEGDSYHNATTVNG-----------------TPVNHQPLER---------------------------HRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLS-EPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSD-------------------------------------------------------------------------------------------------------------------------------------------------SVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKP------------------------------ATDPVLQVVYKSQGKESPGEEF-------------------SAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFR---LVVKADGNQETNNGCHKVKIMPCPFPVAKEPST--KGLNPNPSHQMTKRKRVVLVK-ERKAAQTLSAILLAFIITWTPYNIMVLVS--TFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGN-----SKLP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7E2-1", "uniprot_id": "A0AB32T7E2_DANRE", "id": "A0AB32T7E2-1", "name": "Muscarinic acetylcholine receptor", "aln": "------------------------------MGVENLTLRANIT----------------------DVQLVT---------------------------HSLWEVIAIATVSAIVSFITIIGNILVMLSFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTSYILMGYWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPPILCWQYFVGKRTVPERQCQIQFFS-EPVITFGTAIAAFYFPVSVMTILYCRIYKETERRTKDLAELQGIN-------------------------------------------------------------------------------------------------------------------------------------------------SSTNSS--GDAQPQKIRSCFGC-------------------KHVSNTSRTQALSHTNAAKTLHDQLTNFNSYASSEEEDRS------------------------------GN---FQESCRHQENKS----------------------------------------ESYEEENFFPTPVKASPTKTKKCVSYKFKPKDVSPLKNTNGDAKPGASSFSSAESVNAPSSSSSS--KPIDGTLKCQITKRKRMVLIK-EKKAAQTLSAILLAFILTWTPYNIMVLIS--TFCSDCIPLSLWHLGYWLCYVNSTVNPMCYALCNKTFQKTFRMLLLCQWRKQRAEEKLYWCGQNPAVGSKLT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16395-1", "uniprot_id": "ACM1_DROME", "id": "P16395-1", "name": "Muscarinic acetylcholine receptor DM1", "aln": "MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCKWHTRNREGMVRGVYN-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . :: *: **::*::::*:: .*:*:.**:*:**. **: ** :** *:: : . * :* .** **::**:.*****:***:*******.:*:**:* .:** . *.:**. ** :*::**.* * * :. * *** :* ***:. : :** **:****:** * ** :* :. * : . : . . . . :: : * *.::*: ***.:* **:***::**:. * * *:* * : * ***:***:** ****** :*: *: :* *: ", "identical_positions": 120, "similar_positions": 92, "identity": "14.67%" }, { "cls_id": "homologset.agr.FB:FBgn0000038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25109-1", "uniprot_id": "ACHB_RAT", "id": "P25109-1", "name": "Acetylcholine receptor subunit beta", "aln": "-----------MALGALLLILGILGTPLA--------------------------PGARGSEAEGQLLKKLFSD--YDSSVRPAQEVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIESLRVTAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGPDPDGQ---ERQEIYIHEGTFIENGQWEIIHKPSRLIHLPGDRRGGKEGHREEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMILVTFSVILSVVVLNLHHRSPHTHQ-MPFWVRQIFIHKLPPYLGLKRPKPER----------DQLPEPHHSFSPRSGWG---RGTDEYFIRKPPCDFLFPKLNRFQPESPAP--------DLRRFIDGPPRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09690-1", "uniprot_id": "ACHB_MOUSE", "id": "P09690-1", "name": "Acetylcholine receptor subunit beta", "aln": "-----------MALGALLLLLGVLGTPLA--------------------------PGARGSEAEGQLIKKLFSN--YDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGE---ERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQ-MPFWVRQIFIHKLPPYLGLKRPKPER----------DQLPEPHHSLSPRSGWG---RGTDEYFIRKPPSDFLFPKLNRFQPESSAP--------DLRRFIDGPTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11230-1", "uniprot_id": "ACHB_HUMAN", "id": "P11230-1", "name": "Acetylcholine receptor subunit beta", "aln": "-----------MTPGALLMLLGALGAPLA--------------------------PGVRGSEAEGRLREKLFSG--YDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQ---GHQEIHIHEGTFIENGQWEIIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQ-MPLWVRQIFIHKLPLYLRLKRPKPER----------DLMPEPPHCSSPGSGWG---RGTDEYFIRKPPSDFLFPKPNRFQPELSAP--------DLRRFIDGPNRAVALLPELREVVSSISYIARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIIFTSVGTLVIFLDATYHLPPPDPFP-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TW53-1", "uniprot_id": "A0AB32TW53_DANRE", "id": "A0AB32TW53-1", "name": "Acetylcholine receptor subunit beta", "aln": "-------------MNTMLWVL--WCCWLL--------------------------ALTEASEAERRLLEDLFQD--YNLKVRPARTWNERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPED----YDKIDVVRIPPVKVWRPDIYLINNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMVFRSYTYDSSEVDLQYGLDEDGN---ELHEIVIDENAFTENGEWQICHKPS--------RKNVQDDLYEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAG-EKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHRTPSTHH-MPGWVRKVFINLLPRYLGVLRPTPEE----------PVEEEPKEN-VPMGCLGNSLRPGGEYFIRKINPELVMP--WRGSHNESTV--------KLQRFSNSDNYCLILPPNLKSAIAAITYMSEQLKKQDVDDTMTDDWQYIAVVLDRLFLWLFVVITTLGTLTMFLDASFNYTPDQPFP-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18916-1", "uniprot_id": "ACHG_RAT", "id": "P18916-1", "name": "Acetylcholine receptor subunit gamma", "aln": "----------MHGGQGPQLLLLLLATCL----------------------------GAQSRNQEERLLADLMRN--YDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKD----YEGLWILRVPSTMVWQPDIVLGNNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLVFQSQTYSTSEINLQLS-QEDGQ---AIEWIFIDPEAFTENGEWAIRHRPAKMLLDP--VTPAEEAGHQKVVFYLLIQRKPLFYVINIIVPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHS-MARGVRKVFLRLLPQLLRMHVHPRAP----------AAVQDARLRLQNGSSSGWPIMTREEGDLCLPRSELLFRQR-QRNGLVQAVLEKLENGPEMRQSQEFCGSLKQASPAIQACVDACNLMARARHQQSHFDSGNEEWLLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04760-1", "uniprot_id": "ACHG_MOUSE", "id": "P04760-1", "name": "Acetylcholine receptor subunit gamma", "aln": "----------MQGGQRPHLLLLLLAVCL----------------------------GAQSRNQEERLLADLMRN--YDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKD----YEGLWILRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLIFQSQTYSTSEINLQLS-QEDGQ---AIEWIFIDPEAFTENGEWAIRHRPAKMLLDS--VAPAEEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHS-MARGVRKLFLRLLPQLLRMHVRPLAP----------AAVQDARFRLQNGSSSGWPIMAREEGDLCLPRSELLFRQR-QRNGLVQAVLEKLENGPEVRQSQEFCGSLKQASPAIQACVDACNLMARARRQQSHFDSGNEEWLLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07510-1", "uniprot_id": "ACHG_HUMAN", "id": "P07510-1", "name": "Acetylcholine receptor subunit gamma", "aln": "----------MHGGQGPLLLLLLLAVCL----------------------------GAQGRNQEERLLADLMQN--YDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRD----YEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLS-QEDGQ---TIEWIFIDPEAFTENGEWAIQHRPAKMLLDP--AAPAQEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIHFLPAKAGGQKCTVAINVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLLVVTILIVVNAVVVLNVSLRSPHTHS-MARGVRKVFLRLLPQLLRMHVRPLAP----------AAVQDTQSRLQNGSS-GWSITTGEEVALCLPRSELLFQQW-QRQGLVAAALEKLEKGPELGLSQ-FCGSLKQAAPAIQACVEACNLIACARHQQSHFDNGNEEWFLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNRVPALPFPGDPRPYLPSPD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9V1-1", "uniprot_id": "E7F9V1_DANRE", "id": "E7F9V1-1", "name": "", "aln": "---------MDQNLSSKIIWLWILLFRF----------------------------SGALCNLEGSLHRDLMVG--YNKNIRPVESHEDIIDVKIKMTLTNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLENNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLS-DEDNV---TMEWIEIDPEAFTENGEWMIKHRPAKKVINK--RYRPDELEHQEIIFFLIIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPETSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHP-MSNTIRKVLLNILPRVLRMTMQRWTPEQEEGDFK-MFALGNGTPLRRRRRSSLGLIAKADEYMFRTARSELMFSRLKERKGLLKNTLEKIQNGLGGNTAQDLECSLAAASPEVQQCVSSCKHIAESTKHQNDFQSKNEEWFLVARVIDRMCFFVMALLFILGTIGIFLTGHFNQAPSQPFPGDPKKYLPEISAGDIPG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20782-1", "uniprot_id": "ACHE_MOUSE", "id": "P20782-1", "name": "Acetylcholine receptor subunit epsilon", "aln": "------------MAGALLGALLLLTLFG----------------------------RSQGKNEELSLYHHLFDN--YDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIDWHDYRLNYSKDD----FAGVGILRVPSEHVWLPEIVLENNIDGQFGVAYDSNVLVYEGGYVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFIFAVDDDGN---TINKIDIDTAAFTENGEWAIDYCPGMIRRYE--GGSTEGPGETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHA-TSPRLRQILLELLPRLLGSSPPPEDP-----------RTASP----ARRASSVGILLRAEELILKKPRSELVFEGQRHRHG--------------TWT-AALCQNLGAAAPEIRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYPPCIQP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09660-1", "uniprot_id": "ACHE_RAT", "id": "P09660-1", "name": "Acetylcholine receptor subunit epsilon", "aln": "------------MTMALLGTLLLLALFG----------------------------RSQGKNEELSLYHHLFDN--YDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIEWQDYRLNFSKDD----FAGVEILRVPSEHVWLPEIVLENNIDGQFGVAYDCNVLVYEGGSVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVELIFAVDDDGN---AINKIDIDTAAFTENGEWAIDYCPGMIRHYE--GGSTEDPGETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHA-TSPRLRQILLELLPRLLGLSPPPEDP-----------GAASP----ARRASSVGILLRAEELILKKPRSELVFEGQRHRHG--------------TWTAAALCQNLGAAAPEVRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYPPCIQP------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04844-1", "uniprot_id": "ACHE_HUMAN", "id": "Q04844-1", "name": "Acetylcholine receptor subunit epsilon", "aln": "------------MARAPLGVLLLLGLLG----------------------------RGVGKNEELRLYHHLFNN--YDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDD----FGGIETLRVPSELVWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGK---TINKIDIDTEAYTENGEWAIDFCPGVIRRHH--GGATDGPGETDVIYSLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRFLIFVMVVATLIVMNCVIVLNVSQRTPTTHA-MSPRLRHVLLELLPRLLGSPPPPEAP-----------RAASP----PRRASSVGLLLRAEELILKKPRSELVFEGQRHRQG--------------TWT-AAFCQSLGAAAPEVRCCVDAVNFVAESTRDQEATGEEVSDWVRMGNALDNICFWAALVLFSVGSSLIFLGAYFNRVPDLPYAPCIQP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BG85-1", "uniprot_id": "A2BG85_DANRE", "id": "A2BG85-1", "name": "", "aln": "------MAVAERFGRTCVVAIALLATVL----------------------------QVTG-NEESQLIADKFKN--YSKNIRPARHADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSE----YHDIEQIRVPYYTVWLPDIVLENNIDGKFDVAYYANVLISSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGK---PIEWVDIDPEAFTENGEWAIKHRPARKLTNQ--RYSPDDLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLRSPSTHN-MSQSIKHIFLEVVPRYLGMAPFVDEG-----------DQGGVYEMRERRRSSFGLMQRAEEYVLKQPRSEMMFDKQRERHGLMRTIVDEID----VSSTANLYKSLAKTAPEIKECVDACNFIAESTKQQNDTGSEMESWVLIGKMIDKVCFWAAISLFSIGTIAIFLMGHYNQAPEYPFAWENKKYVPE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25110-1", "uniprot_id": "ACHD_RAT", "id": "P25110-1", "name": "Acetylcholine receptor subunit delta", "aln": "----------MAGPVPTLGLLAALVVC-----------------------------GSWGLNEEQRLIQHLFEEKGYNKELRPVARKEDIVDVALSLTLSNLISLKEVEETLTTNVWIDHAWIDSRLQWNANE----FGNITVLRLPSDMVWLPEIVLENNNDGSFQISYACNVLVSDSGHVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEIRLSLKQEEEDNRSYPIEWIIIDPEGFTENGEWEIVHRAAKVNVDP--SVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCG-EKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHV-LSEGVKKFFLETLPKLLHMSRPEEED--------------PGPRALIRRTSSLGYISKAEEYFSLKSRSDLMFEKQSERHGLARRLTT------ARKPPASSEQVQQELFNEMKPAVDGANFIVNHMRDQNSYNEEKDNWNQVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPPQPFPGDPFSYDEQDRRFI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02716-1", "uniprot_id": "ACHD_MOUSE", "id": "P02716-1", "name": "Acetylcholine receptor subunit delta", "aln": "----------MAGPVLTLGLLAALVVCAL--------------------------PGSWGLNEEQRLIQHLFNEKGYDKDLRPVARKEDKVDVALSLTLSNLISLKEVEETLTTNVWIDHAWVDSRLQWDAND----FGNITVLRLPPDMVWLPEIVLENNNDGSFQISYACNVLVYDSGYVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQEEENNRSYPIEWIIIDPEGFTENGEWEIVHRAAKLNVDP--SVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCG-EKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHV-LSEGVKKFFLETLPKLLHMSRPAEED--------------PGPRALIRRSSSLGYICKAEEYFSLKSRSDLMFEKQSERHGLARRLTT------ARRPPASSEQVQQELFNEMKPAVDGANFIVNHMRDQNSYNEEKDNWNQVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPLQPFPGDPFSYSEQDKRFI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07001-1", "uniprot_id": "ACHD_HUMAN", "id": "Q07001-1", "name": "Acetylcholine receptor subunit delta", "aln": "----------MEGPVLTLGLLAALAVC-----------------------------GSWGLNEEERLIRHLFQEKGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEE----FGNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEIVHRPARVNVDP--RAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPADSG-EKTSVAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHV-LSEGVKKLFLETLPELLHMSRPAEDG--------------PSPGALVRRSSSLGYISKAEEYFLLKSRSDLMFEKQSERHGLARRLTT------ARRPPASSEQAQQELFNELKPAVDGANFIVNHMRDQNNYNEEKDSWNRVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPPQPFPGDPYSYNVQDKRFI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15822-1", "uniprot_id": "ACHA2_HUMAN", "id": "Q15822-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-----MGPSCPVFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDRLFKHLFRG--YNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTD----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQT------------VDLKDYWESGEWAIVNATGTYNSKK--YDCCAE-IYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHT-MPHWVRGALLGCVPRWLLMNRPPPPVELCHPLRL---KLSPSYHWLESNVDAEEREVVVEEEDR-----WACAGHVAPSVGTLCSHGHLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLPPFLAGMI----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12389-1", "uniprot_id": "ACHA2_RAT", "id": "P12389-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-----MTLSHSALQFWTHLYLWCLLLVPA-----------------------VLTQQGSHTHAEDRLFKHLFGG--YNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNVTSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERT------------VDLKDYWESGEWAIINATGTYNSKK--YDCCAE-IYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRPLPPMELHGSPDL---KLSPSYHWLETNMDAGEREETEEEEEEEDENICVCAGLPDSSMGVLYGHGGLHLRAMEPETKTPSQASEILLSPQIQKALEGVHYIADRLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30532-1", "uniprot_id": "ACHA5_HUMAN", "id": "P30532-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "MAARGSGPRALRLLLLVQLVAGRCGLAGAAG-----------------GAQRGLSEPSSIAKHEDSLLKDLFQD--YERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKVIRVPSDSVWTPDIVLFDNADGRFEG-TSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD------------VDKRDFFDNGEWEIVSATGSKGNRT--DSCC---WYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEG-EKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMR------------------------------SHVDRYFT-QKEETE------------------------------------SGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPVIYKWANILIPVHIGNANK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20420-1", "uniprot_id": "ACHA5_RAT", "id": "P20420-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "---------------MVQLLAGRWRPTGARR-----------------GTRGGLPELSSAAKHEDSLFRDLFED--YERWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD------------VDRTDFFDNGEWEIMSAMGSKGNRT--DSCC---WYPYITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMR------------------------------SHADRYFT-QREEAE------------------------------------SGAGPKS-RNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05901-1", "uniprot_id": "ACHB3_HUMAN", "id": "Q05901-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "---------MLPDFMLVLIVLG--IPSSATT-----------------GFN-------SIAENEDALLRHLFQG--YQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDD----YGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN------------VDRKDFFDNGEWEILNAKGMKGNRR--DGVY---SYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMK------------------------------DHVDRYSSPEKEESQP---------------------VVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02708-2", "uniprot_id": "ACHA_HUMAN", "id": "P02708-2", "name": "Acetylcholine receptor subunit alpha", "aln": "---------MEPWPLLLLFSLCSAGLVLG-------------------------------SEHETRLVAKLFKD--YSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDD----YGGVKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQ------------PDLSNFMESGEWVIKESRGWKHSVT--YSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSG-EKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHV-MPNWVRKVFIDTIPNIMFFS----------------------------TMKRPSREKQDKKIFTED--------------------IDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQQG--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04755-1", "uniprot_id": "ACH3_DROME", "id": "P04755-1", "name": "Acetylcholine receptor subunit beta-like 1", "aln": "-----MESSCKSWLLCSILVLVAFSLVSA-------------------------------SEDEERLVRDLFRG--YNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQIMKSNVWLRLVWYDYQLQWDEAD----YGGIGVLRLPPDKVWKPDIVLFNNADGNYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKN---F-------VDLSDYWKSGTWDIIEVPAYLNVYE--GDSNHP-TETDITFYIIIRRKTLFYTVNLILPTVLISFLCVLVFYLPAEAG-EKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVIIINWNFRGPRTHR-MPMYIRSIFLHYLPAFLFMKRPRKTRLRWMMEMPGMSMPAHPHPSYGSPAELPKHISAIGGKQSKMEVMELSDLHHPNCKINRKVNSGGELGLGDGCRRESESSDSILLSPEASKATEAVEFIAEHLRNEDLYIQTREDWKYVAMVIDRLQLYIFFIVTTAGTVGILMDAPHIFEYVDQDRIIEIYRGK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17787-1", "uniprot_id": "ACHB2_HUMAN", "id": "P17787-1", "name": "Neuronal acetylcholine receptor subunit beta-2", "aln": "-----MARRCGPVALLLGFGLLRLCSG------------------------------VWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEE----FDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEV------------ASLDDFTPSGEWDIVALPGRRNENP--DDST----YVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG-EKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHT-MAPWVKVVFLEKLPALLFMQQPRHHC-------------ARQRLRLRRRQREREGAGALFFREAPGADS-----CTCFVNRASVQGLAGAFG-AEPAPVAGPGRSGEPCGCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTTTTFLHSDHSAPSSK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12390-1", "uniprot_id": "ACHB2_RAT", "id": "P12390-1", "name": "Neuronal acetylcholine receptor subunit beta-2", "aln": "-----MAGHSNSMALFS-FSLLWLCSG------------------------------VLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPED----FDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSDV------------ASLDDFTPSGEWDIIALPGRRNENP--DDST----YVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCG-EKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHT-MAPWVKVVFLEKLPTLLFLQQPRHRC-------------ARQRLRLRRRQREREGAGALFFREGPAADP-----CTCFVNPASVQGLAGAFR-AEPT-AAGPGRSVGPCSCGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTVGMFLQPLFQNYTATTFLHPDHSAPSSK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B0F4-1", "uniprot_id": "A0A8M3B0F4_DANRE", "id": "A0A8M3B0F4-1", "name": "", "aln": "-----MGSTMGSNCLLY-LCLLWLCVAR-----------------------------SLAADAEERLVDFLLGPERYNKLIRPAVNKSQQVTIGIKVSLAQLISVNEREQIMTTNVWLTQEWNDYRLVWDPNE----YEGIKKLRIPSRHIWLPDIVLYNNADGVYEVSFYCNAVVSNTGDIFWLPPAIYKSACAIEVRNFPFDQQNCTLKFRSWTYDRTELDLYLTSDF------------ASRDDYTPSGEWDIVSLPGRRNEDL--SDPT----YLDVTYDFVIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCG-EKMTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHR-MPEWVKRVFLHKLPFFLLMRRPGRSN-------------VRERFR-RKHQRKSFSSDTKGLR--LDGDS-----YFLSDDPGRVCG-AWRVG-DLPEGSEFRQRVKVRHDPDVDEAIEGVRFIAEHMKIEDDDEGIIEDWKYVAMVIDRLFLWIFILVCVVGTLGLFVQPLFQSYN-TPVAEEEYGDF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12392-1", "uniprot_id": "ACHB4_RAT", "id": "P12392-1", "name": "Neuronal acetylcholine receptor subunit beta-4", "aln": "--------MRGTP-LLLVSLFSLLQDGD-----------------------------CRLANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIRLELSLSQLISVNEREQIMTTSIWLKQEWTDYRLAWNSSC----YEGVNILRIPAKRVWLPDIVLYNNADGTYEVSVYTNVIVRSNGSIQWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVLKSPT------------AIMDDFTPSGEWDIVALPGRRTVNP--QDPS----YVDVTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCG-EKMTLCISVLLALTFFLLLISKIVPPTSLDIPLIGKYLLFTMVLVTFSIVTTVCVLNVHHRSPSTHT-MASWVKECFLHKLPTFLFMKRPGLEV-------------SLVRVPHPSQLHLATADTAATSALGPTSPSNLYGSSMYFVNPVPAAPKSAVSSHTAGLPRDARLRSSGRFREDLQEALEGVSFIAQHLESDDRDQSVIEDWKFVAMVVDRLFLWVFVFVCILGTMGLFLPPLFQIHAPSKDS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R493-1", "uniprot_id": "ACHB4_MOUSE", "id": "Q8R493-1", "name": "Neuronal acetylcholine receptor subunit beta-4", "aln": "--------MRGTP-LLLVSLFALLQPGD-----------------------------CRLANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIRLELSLSQLISVNEREQIMTTSIWLKQEWTDYRLAWNSSC----YEGVNILRIPAKRVWLPDIVLYNNADGTYEVSVYTNVIVRSNGSIQWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVLKSPT------------AIMDDFTPSGEWDIVALPGRRTVNP--QDPS----YVDVTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCG-EKMTLCISVLLALTFFLLLISKIVPPTSLDIPLIGKYLLFTMVLVTFSIVTTVCVLNVHHRSPSTHT-MASWVKECFLHKLPTFLFMKRPGLEV-------------SPARVPHSSQLHLTTAEATSTSALGPSSPSNLYGNSMYFVNPVPATPKSAVSSHTAGLPRDARLRSSGRFRQDLQEALEGVSFIAQHLESDDRDQSVIEDWKFVAMVVDRLFLWVFVIVCILGTMGLFLPPLFQIHAPSKGL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30926-1", "uniprot_id": "ACHB4_HUMAN", "id": "P30926-1", "name": "Neuronal acetylcholine receptor subunit beta-4", "aln": "--------MRRAPSLVLFFLVALCGRGN-----------------------------CRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSR----YEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPT------------ASMDDFTPSGEWDIVALPGRRTVNP--QDPS----YVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCG-EKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHT-MAPWVKRCFLHKLPTFLFMKRPGPDS-------------SPARAFPPSKSCVTKPEATATS----TSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD-----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * : *. **. : : : . : : :*:.:.: : :.: : : * * .* : . : :::. :* *:: * :* ** : . : * : * *. ::* * : : **** *.* : : : .: : : : .* * * . : : :::.* .*:: : :: * : : . .:** * :* : *: .*:::: . :* :* :*:: .:: * : . : : :* * . *: . :: :: :* : : : .* :. :*.: : . *: :: ", "identical_positions": 49, "similar_positions": 115, "identity": "8.35%" }, { "cls_id": "homologset.agr.FB:FBgn0000039", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12389-1", "uniprot_id": "ACHA2_RAT", "id": "P12389-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-------MTLSHSALQFWTHLYLWCLLLVPA-----------------------VLTQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNVTSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERT----------VDLKDYWESGEWAIINATG---TYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRP-----------------------------------------LPPMELHGSPDLKLSPSYHWLETN--------MDAGERE----------------------------------ETEEEEEEE-DENICVCAGLPDSS-------MGVLYGHGGLHLRAMEPETKTPSQA------------------------SEILLSPQIQKALEGVHYIADRLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLF--LPPFLAGMI---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X60-1", "uniprot_id": "ACHA2_MOUSE", "id": "Q91X60-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-------MAPSHPAFQFWIHLYLWCLLLMPA-----------------------VLAQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERT----------VDLKDYWESGEWAIINATG---TYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRP-----------------------------------------LPPMELHGSPGLKLSPTYHWLETN--------MDAEERE----------------------------------ETEEEEEEEEDENICMCAGLPDSS-------MGVLYGHGSLHLRAMGPEAKTPSQA------------------------SEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLF--LPPFLAGMI---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15822-1", "uniprot_id": "ACHA2_HUMAN", "id": "Q15822-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-------MGPSCPVFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDRLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTD----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQT----------VDLKDYWESGEWAIVNATG---TYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHT-MPHWVRGALLGCVPRWLLMNRP-----------------------------------------PPPVELCHPLRLKLSPSYHWLESN--------VDAEERE----------------------------------VVVEE------EDRWACAGHVAPS-------VGTLCSHGHLHSGASGPKAEALLQE------------------------GELLLSPHMQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLF--LPPFLAGMI---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43681-1", "uniprot_id": "ACHA4_HUMAN", "id": "P43681-1", "name": "Neuronal acetylcholine receptor subunit alpha-4", "aln": "----MELGGPGAPRLLPPLLLLLGTGLLRAS-------------------------SHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPAD----YENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSR----------VDQLDFWESGEWVIVDAVG---TYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHT-MPTWVRRVFLDIVPRLLLMKRPSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPATSGTQSLHPPSPSFCVPLDVPAEPGPSCKSPSDQLPPQQPLEAEKASPHPSPGPCRPPHGTQAPGLAKARSLSVQHMSSPGEAVEGGVRCRSRSIQYCVPRDDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSVSPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLF--LPPWLAGMI---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43143-1", "uniprot_id": "ACHA6_RAT", "id": "P43143-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "-----MLNGWGRGDLRSGLCLWICGFLAFFK---------------------------GSRGCVSEEQLFHTLFAHYNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTE----YDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK----------VDMNDFWENSEWEIVDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHT-MPKWVKTMFLQVFPSILMMRRPLD-------------------------------------------KTKEMDGVKDPKTHTKRPAK------------------------------------------------VKFTHRKEPKLLKECRHCHK-------------SSEIAPGKRLS-QQPAQWVTENSE----------------------------HPPDVEDVIDSVQFIAENMKSHNETKEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLF--LQPLLGNTGAS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0W9-1", "uniprot_id": "ACHA6_MOUSE", "id": "Q9R0W9-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "-----MLNSRDQGNLHSGLCLWLCGFLALFK---------------------------GSTGCESEEQLFHRLFAHYNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTE----YDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK----------VDMNDFWENSEWEIVDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHT-MPKWVKTIFLQAFPSILMMRKPLD-------------------------------------------KTKEAGGVKDPKSHTKRPAK------------------------------------------------VKFTHRGESKLLKECHHCQK-------------SSDIAPGKRRSSQQPARWVAENSE----------------------------HSSDVEDVIESVQFIAENMKSHNETNEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLF--LQPLLGNTGKS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04757-1", "uniprot_id": "ACHA3_RAT", "id": "P04757-1", "name": "Neuronal acetylcholine receptor subunit alpha-3", "aln": "---------MGVVLLPPPLSMLML-VLMLLP---------------------------AASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSD----YQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS----------MNLKDYWESGEWAIIKAPG---YKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT-MPTWVKAVFLNLLPRVMFMTRPTSGE-------------------------------------GDTPKTRTFYGAELSNLNCFSRAD------------------------------------------------SKSCKEGYPCQDGTCGYCHHRRVKI--------SNFSANLTRSSSSESVNAVLSLSA----------------------------LSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLF--LQPLMARDDT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4G9-1", "uniprot_id": "ACHA3_MOUSE", "id": "Q8R4G9-1", "name": "Neuronal acetylcholine receptor subunit alpha-3", "aln": "---------MGVVLPPPPLSMLML-VLMLLP---------------------------VASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSD----YQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS----------MNLKDYWESGEWAIIKAPG---YKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT-MPTWVKAVFLNLLPRVMFMTRPTSTE-------------------------------------EDAPKTRNFYGAELSNLNCFSRAD------------------------------------------------SKSCKEGYPCQDGTCGYCHHRRVKI--------SNFSANLTRSSSSESVDAVLSLSA----------------------------LSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLF--LQPLMARDDT--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12391-1", "uniprot_id": "ACHB3_RAT", "id": "P12391-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "-----MTGFLRVFLVLSATLSGSWVTLTATAG--------------------------LSSVAEHEDALLRHLFQGYQKWVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEE----YGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN----------VDRKDFFDNGEWEILNAKG---MKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQRLPRWLCMKDP-----------------------------------------------MDRFSFPDGK--------------------------------------------------------------------------------------------ESDTAVRGKVSGKRKQTPASD------------------------GERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIASVLGSILIF--IPALKMWIHRFH------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMN3-1", "uniprot_id": "ACHB3_MOUSE", "id": "Q8BMN3-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "-----MTGFLRVFLALSATLSGSWVTLTATAG--------------------------LSSVAEHEDALLRHLFQGYQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPED----YGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTYDGTMVDLILINEN----------VDRKDFFDNGEWEILNAKG---MKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCMKDP-----------------------------------------------RDRFSFPDGT--------------------------------------------------------------------------------------------ESKGTVRGKFPGKKKQTPTSD------------------------GERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTASVLGSVLIF--IPALKMWIHRFH------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20420-1", "uniprot_id": "ACHA5_RAT", "id": "P20420-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "---------------MVQLLAGRWRPTGARRGTRG-------------------GLPELSSAAKHEDSLFRDLFEDYERWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD----------VDRTDFFDNGEWEIMSAMG---SKGNRTDSCCW--YPYITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSH-----------------------------------------------ADRY-FTQRE--------------------------------------------------------------------------------------------EAE-----SGAGPKSRN-----------------------------------TLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLF--VPVIYKWANIIVPVHIGNTIK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2MKA5-1", "uniprot_id": "ACHA5_MOUSE", "id": "Q2MKA5-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "MAARGSRRRALRLLLMVQLLAGRWRPAGAARGARG-------------------GLPELSSAAKHEDSLFRDLFEDYEKWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD----------VDRTDFFDNGEWEIMSAMG---SKGNRTDSCCW--YPCITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSH-----------------------------------------------ADRY-FTQRE--------------------------------------------------------------------------------------------EAE-----KDGGPKSRN-----------------------------------TLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLF--VPVIYKWANIIVPVHIGNTIK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17644-1", "uniprot_id": "ACH2_DROME", "id": "P17644-1", "name": "Acetylcholine receptor subunit alpha-like 2", "aln": "----MAPGCCTTRPRPIALLAHIWRHCKPLCLLLVL-----------------LLLCETVQANPDAKRLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSE----YGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPA---ERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSG-EKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHK-MRPWIRSFFIKRLPKLLLMRVPKDLLR-------------------------------------DLAANKINYGLKFSKTKFGQALMDEMQMNSGGSSPDSLRR-------------------------------MQGRVGAGGCNGMHVTTATNRFSGLVGALGGGLSTLSGYNGLPSVLSGLDDSLSDVAAR------------------------KKYPFELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDTKAIDVQLSDVAKQIYNLTEKKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F9V1-1", "uniprot_id": "E7F9V1_DANRE", "id": "E7F9V1-1", "name": "", "aln": "-----------MDQNLSSKIIWLWILLFRFS---------------------------GALC-NLEGSLHRDLMVGYNKNIRPVESHEDIIDVKIKMTLTNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLENNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLS-DEDNVTME-WIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELE--HQEIIFFLIIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPETSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHP-MSNTIRKVLLNILPRVLRMTMQRW------------------------------------------TPEQEEGDFKMFALGNGTPLR------------------------------------------------RRRRSS-LGLIAKADEYMFRTARSE--------LMFSRL-KERKGLLKNTLEKIQNGLGGNTAQDL-------------ECSLAAASPEVQQCVSSCKHIAESTKHQNDFQSKNEEWFLVARVIDRMCFFVMALLFILGTIGIFLTGHFNQAPSQPFPGDPKKYLPEISAGDIPG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20782-1", "uniprot_id": "ACHE_MOUSE", "id": "P20782-1", "name": "Acetylcholine receptor subunit epsilon", "aln": "---------------MAGALLGALLLLTLFG---------------------------RSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIDWHDYRLNYSKDD----FAGVGILRVPSEHVWLPEIVLENNIDGQFGVAYDSNVLVYEGGYVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFIFAVDDDGNTIN-KIDIDTAAFTENGEWAIDYCPGMIRRYEGGSTEGPG--ETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHA-TSPRLRQILLELLPRLLGS-----------------------------------------------SPPPED---------PRTASP------------------------------------------------ARRASS-VGILLRAEELILKKPRSE--------LVFEGQ-RHRHGTWTAALC--QN--------------------------LGAAAPEIRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYP-------PCIQP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09690-1", "uniprot_id": "ACHB_MOUSE", "id": "P09690-1", "name": "Acetylcholine receptor subunit beta", "aln": "-------------MALGALLLLLGVLGTPLAP--------------------------GARGSEAEGQLIKKLFSNYDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGEERQ-EVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQ-MPFWVRQIFIHKLPPYLGLK----------------------------------------------RPKPER---------DQLPEP------------------------------------------------HHSLSPRSGWGRGTDEYFIRKPPSD--------FLFPKLNRFQPESSAPDLRRFIDG----------------------PTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: *: **. . : : : : :::* .:: :: : * ::: * * :: : . .: : :.:. :* *:: * :* * : :. : * : * *. ::*:* :.: :**** *.* : * * :*: : : :. : . :* * . : : : ::* .:** : :* **: :: * :..::**.. * :* : *: *:*:::: . :*.:* :*:: .**:* * .. : :: :. :*: *.. *: :: :: .* : : .: .. .:* :. .:*.: :: .*: :: ", "identical_positions": 58, "similar_positions": 133, "identity": "8.31%" }, { "cls_id": "homologset.agr.FB:FBgn0000042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVI7-1", "uniprot_id": "ACTB1_DANRE", "id": "Q7ZVI7-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZVF9-1", "uniprot_id": "ACTB2_DANRE", "id": "Q7ZVF9-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10987-1", "uniprot_id": "ACT1_DROME", "id": "P10987-1", "name": "Actin-5C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZRN3-1", "uniprot_id": "D3ZRN3_RAT", "id": "D3ZRN3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDDELGALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGNVMDSGDGVTHTVPIYEGYALPHGILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A5A3E0-1", "uniprot_id": "POTEF_HUMAN", "id": "A5A3E0-1", "name": "POTE ankyrin domain family member F", "aln": "MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCCRESGKSNVGTSGDHDDSAMKTLRSKMGKWCRHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSSKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEATLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTEHGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATVASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6S8J3-1", "uniprot_id": "POTEE_HUMAN", "id": "Q6S8J3-1", "name": "POTE ankyrin domain family member E", "aln": "MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSKMGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVPSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG38-1", "uniprot_id": "POTEI_HUMAN", "id": "P0CG38-1", "name": "POTE ankyrin domain family member I", "aln": "MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSKMGKWCCHCFPCCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSNVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAMLSLYTSGRTTGIVMDSGDGVTHTVPIYDGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMAMAASSSSLEKSYELPDGQVITIGNEWFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMLKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG39-1", "uniprot_id": "POTEJ_HUMAN", "id": "P0CG39-1", "name": "POTE ankyrin domain family member J", "aln": "MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSKMGKWCCHCFPCCRGSGKS-------------------------------------NVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKERDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGCPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAMLSLYTSGRTTGIVMDSGDGVTHTVPIYDGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMAMVASSSSLEKSYELPDGQVITISNEWFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYX7-1", "uniprot_id": "ACTBM_HUMAN", "id": "Q9BYX7-1", "name": "Putative beta-actin-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDTAVLVIDNGSGMCKAGFAGDDAPQAVFPSIVGRPRHQGMMEGMHQKESYVGKEAQSKRGMLTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYTSGRTTGIVMDSGDGFTHTVPIYEGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTTAEQEIVRDIKEKLCYVALDSEQEMAMAASSSSVEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHKTTFNSIVKSDVDIRKDLYTNTVLSGGTTMYPGIAHRMQKEITALAPSIMKIKIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: ..**:***********.*****:*****:** **:**:* ** **:.***.*******:***:**:***::**********:***********:***:*****.:*** ***********:**.**:**:***: ***:****** *:*****.:*.**** * :***. **:*****:*.*******:*:** *:* **:*****:********** **** .* ***:*:************.** **.***:*:*..**:*: **.:**:***:*.***:**:** * *:***:**:**:*.******.:**** :*::*****:******:********:**************:**.***:**:", "identical_positions": 274, "similar_positions": 79, "identity": "25.49%" }, { "cls_id": "homologset.agr.FB:FBgn0000043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVI7-1", "uniprot_id": "ACTB1_DANRE", "id": "Q7ZVI7-1", "name": "Actin, cytoplasmic 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZVF9-1", "uniprot_id": "ACTB2_DANRE", "id": "Q7ZVF9-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02572-1", "uniprot_id": "ACT2_DROME", "id": "P02572-1", "name": "Actin-42A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CG38-1", "uniprot_id": "POTEI_HUMAN", "id": "P0CG38-1", "name": "POTE ankyrin domain family member I", "aln": "MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSKMGKWCCHCFPCCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSNVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAMLSLYTSGRTTGIVMDSGDGVTHTVPIYDGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMAMAASSSSLEKSYELPDGQVITIGNEWFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMLKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG39-1", "uniprot_id": "POTEJ_HUMAN", "id": "P0CG39-1", "name": "POTE ankyrin domain family member J", "aln": "MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSKMGKWCCHCFPCCRGSGKS-------------------------------------NVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKERDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGCPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAMLSLYTSGRTTGIVMDSGDGVTHTVPIYDGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMAMVASSSSLEKSYELPDGQVITISNEWFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5A3E0-1", "uniprot_id": "POTEF_HUMAN", "id": "A5A3E0-1", "name": "POTE ankyrin domain family member F", "aln": "MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCCRESGKSNVGTSGDHDDSAMKTLRSKMGKWCRHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSSKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEATLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTEHGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATVASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: *.**:************************** **:**:* ** **:****.***********:**:****:**************************:*****.:***:**************.**:**:***:****:********:******:*.**** * :**** **:*****:*.*******:*:** *:* ************************ .*.***:**************.** **.**:**:*..**:*:.**.:**:*****.***:**:** * *:******:**:*.******::**** :*::*:***:******:********:*********************:**:", "identical_positions": 295, "similar_positions": 64, "identity": "27.44%" }, { "cls_id": "homologset.agr.FB:FBgn0000044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "--MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "--MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "--MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "--MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "--MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVI7-1", "uniprot_id": "ACTB1_DANRE", "id": "Q7ZVI7-1", "name": "Actin, cytoplasmic 1", "aln": "--MDEEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZRN3-1", "uniprot_id": "D3ZRN3_RAT", "id": "D3ZRN3-1", "name": "", "aln": "-MVDDELGALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGNVMDSGDGVTHTVPIYEGYALPHGILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53501-1", "uniprot_id": "ACT3_DROME", "id": "P53501-1", "name": "Actin-57B", "aln": "-MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITSLAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P68136-1", "uniprot_id": "ACTS_RAT", "id": "P68136-1", "name": "Actin, alpha skeletal muscle", "aln": "MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "--MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0G2KAE0-1", "uniprot_id": "A0A0G2KAE0_RAT", "id": "A0A0G2KAE0-1", "name": "", "aln": "--MDN--TPIICDYGSGFSKVGFAGTRVPLAVFPTILGKMKNATLLERLEEEDWFIGAEVQNNRPKLNIHYPIFRGAITNWDNVQKVWHYSFYHYLRIAPEQHPILVTDPPLTTKEARSKMTQILFETFNFPALYLANQGVLSLYASGRTSGTTIESGDGMTYFVPIANGYPLHLSTTKVDTAGQDLTVYLMKLLSDNGNMLETTADLEHVRDLKEKCCYVALDYDMEMSKTSESSFLKK-FTLPDGKEISLGQETFMCPEVLFNPSLVGKNYPGIDMQAQQSITSCDKSHWRNLFGYIILSGGTGTCSGLRFRLQREIAKLVSPELSVKVVTSPYAKYGAWVGASILCSLPMFKDMWITNHEYLEIGPSVICRRTF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:: * ***: *.**.* .* ****:::*: :: :: : ::* ::* *.*.:* *.::*** :* :****:::*:*:::**: **:**::** *:*:.*:..* *.*****:**:** **:*:: *.*****:****:* .::****::: *** *:.* . ::* **:*** ****:*::.* : ***: * ***:*** ******:: ** .:: *: ::: : ****: *::*:* * .** :*:**.:* : **. . :** .** . ::*:. ::***: .*: *:*:**. *... :.:*:::.* **..*:*.***.**. *::***::.** * ** :: :: *", "identical_positions": 157, "similar_positions": 137, "identity": "41.64%" }, { "cls_id": "homologset.agr.FB:FBgn0000045", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "-MD-DDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "-MD-DDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "-MD-DDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "-ME-EEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "-ME-EEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVI7-1", "uniprot_id": "ACTB1_DANRE", "id": "Q7ZVI7-1", "name": "Actin, cytoplasmic 1", "aln": "-MD-EEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZRN3-1", "uniprot_id": "D3ZRN3_RAT", "id": "D3ZRN3-1", "name": "", "aln": "MVD-DELGALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGNVMDSGDGVTHTVPIYEGYALPHGILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02574-1", "uniprot_id": "ACT4_DROME", "id": "P02574-1", "name": "Actin, larval muscle", "aln": "MCD-EEASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILSLKYPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRTPEALFQPSFLGMESCGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P68136-1", "uniprot_id": "ACTS_RAT", "id": "P68136-1", "name": "Actin, alpha skeletal muscle", "aln": "MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "-MD-SEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0G2KAE0-1", "uniprot_id": "A0A0G2KAE0_RAT", "id": "A0A0G2KAE0-1", "name": "", "aln": "-MD---NTPIICDYGSGFSKVGFAGTRVPLAVFPTILGKMKNATLLERLEEEDWFIGAEVQNNRPKLNIHYPIFRGAITNWDNVQKVWHYSFYHYLRIAPEQHPILVTDPPLTTKEARSKMTQILFETFNFPALYLANQGVLSLYASGRTSGTTIESGDGMTYFVPIANGYPLHLSTTKVDTAGQDLTVYLMKLLSDNGNMLETTADLEHVRDLKEKCCYVALDYDMEMSKTSESSFLKK-FTLPDGKEISLGQETFMCPEVLFNPSLVGKNYPGIDMQAQQSITSCDKSHWRNLFGYIILSGGTGTCSGLRFRLQREIAKLVSPELSVKVVTSPYAKYGAWVGASILCSLPMFKDMWITNHEYLEIGPSVICRRTF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: * ***: *.**.* .* ****:::*: :: :: : ::* ::* *.*.:* *.::*** :* :****:::*:*:::**: **:**::** *:*:.*:..* *.*****:**:** **:*:: *.*****:****:* .::****::: *** *:.* . ::* **:*** ****:*::.* : ***: * ***:*** ******:: ** .:: *: ::: : ****: *::*:* * **.:*:**.:* : **. . :** .** . ::*:. ::***: .*: *:*:**. *... :.:*:::.* **..*:*.***.**. *::***:::** * ** :: :: *", "identical_positions": 157, "similar_positions": 136, "identity": "41.64%" }, { "cls_id": "homologset.agr.FB:FBgn0000046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY84-1", "uniprot_id": "ACL7A_MOUSE", "id": "Q9QY84-1", "name": "Actin-like protein 7A", "aln": "MSLDGVWAPQTANIGDGPAKKASDQASMQTQVLQTASLKDGPAKRAVWVRRDNAETEDPVKSTMSKDRPR-LEVTKAVVVDLGTGFCKCGFAGLPKPTHKISTTVGKPYMETAK-TGDNRKETFVGHELFNPDIHLKLVNPLRHGIIVDWDTVQDIWEYLFRQEMKIAPEEHAVLVSDPPLSPHTNREKYAEMLFETFNTPAMHIAYQSRLSMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTTYLMNLMNNSGKHFSED-HLGIVEDIKTRCCFVALDPIEEKKIPAPE--HEIHYTLPDGKEIRLGQERFLCSEMFFKP-SLIKSMQLGLHTQTVSCLNKCD-IALKRDLMGNILLCGGSTMLRGFPNRLQKELSSMCPNDTP-QVNVLPERDTAVWTGGSILASLQGFQPLWVHRLEYEEHGPFFLYRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QY83-1", "uniprot_id": "ACL7B_MOUSE", "id": "Q9QY83-1", "name": "Actin-like protein 7B", "aln": "MATKNSPSPKPMGTAQGDPGEAG----------------TLPAPEAAGIR--------DTGSTQLKTKPKKIRKIKALVIDLGSQYCKCGYAGEPRPTYFISSTVGKRSAEMAADAGDNFKETYVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKIMPEEHAVLVSDPPLSPTSNREKYAELLFETFGIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPSRVDYAGCDLTNYLMQLLNEAGHKFSDD-HLHIIEHIKKKCCYAALLPEEEMSLGLDE--LHVDYELPDGKIITIGQERFRCSEMLFKP-SLVGCTQPGLPELTATCLARCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSP-TVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68134-1", "uniprot_id": "ACTS_MOUSE", "id": "P68134-1", "name": "Actin, alpha skeletal muscle", "aln": "-------------------------------------------------------------MCDEDETTA-------LVCDNGSGLVKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68136-1", "uniprot_id": "ACTS_RAT", "id": "P68136-1", "name": "Actin, alpha skeletal muscle", "aln": "-------------------------------------------------------------MCDEDETTA-------LVCDNGSGLVKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TN73-1", "uniprot_id": "A0AB32TN73_DANRE", "id": "A0AB32TN73-1", "name": "", "aln": "-------------------------------------------------------------MCDDDETTA-------LVCDNGSGLVKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62737-1", "uniprot_id": "ACTA_MOUSE", "id": "P62737-1", "name": "Actin, aortic smooth muscle", "aln": "-------------------------------------------------------------MCEEEDSTA-------LVCDNGSGLCKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62738-1", "uniprot_id": "ACTA_RAT", "id": "P62738-1", "name": "Actin, aortic smooth muscle", "aln": "-------------------------------------------------------------MCEEEDSTA-------LVCDNGSGLCKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "---------------------------------------------------------------MDDDIAA-------LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETTFNSIMKCD-VDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "---------------------------------------------------------------MDDDIAA-------LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETTFNSIMKCD-VDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "---------------------------------------------------------------MEEEIAA-------LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETTFNSIMKCD-VDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10981-1", "uniprot_id": "ACT5_DROME", "id": "P10981-1", "name": "Actin-87E", "aln": "--------------------------------------------------------------MCDDEVAA-------LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQP-SFLGMESCGIHETVYNSIMKCD-VDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "---------------------------------------------------------------MDSEVAA-------LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRP-RHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHP-SVLGLESAGIDQTTYNSIMKCD-VDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0G2KAE0-1", "uniprot_id": "A0A0G2KAE0_RAT", "id": "A0A0G2KAE0-1", "name": "", "aln": "-----------------------------------------------------------------MDNTP-------IICDYGSGFSKVGFAGTRVPLAVFPTILGKM-KNATLLERLEEEDWFIGAEVQNNRPKLNIHYPIFRGAITNWDNVQKVWHYSFYHYLRIAPEQHPILVTDPPLTTKEARSKMTQILFETFNFPALYLANQGVLSLYASGRTSGTTIESGDGMTYFVPIANGYPLHLSTTKVDTAGQDLTVYLMKLLSDNGNMLETTADLEHVRDLKEKCCYVALDYDMEMSKTSES-SFLKKFTLPDGKEISLGQETFMCPEVLFNP-SLVGKNYPGIDMQAQQSITSCD-KSHWRNLFGYIILSGGTGTCSGLRFRLQREIAKLVSPELSVKVVTSPYAKYGAWVGASILCSLPMFKDMWITNHEYLEIGPSVICRRTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YYH9-1", "uniprot_id": "D3YYH9_MOUSE", "id": "D3YYH9-1", "name": "", "aln": "-----------------------------------------------------------------MEKTP-------LVCDYGSGFSKVGFSGTQAPQAVFPTILGKM-KHTNVLEGLGEQDWFIGAETQTNRTELNMYYPISRGAITNWDNVEKIWHYSFYHSLQIAPEQHPILITEAPLTSKEAKSRMTQILFETFNFPALYTANQAVLSLIASGRTSGTAIESGDGMTYFVPVMNGYPLHLSTTKLDIAGQDLTLYLMKLLSDNGNVLETIADLEYIRDLKDKYSYVALDYNMEMSKTSAP-SFQKKFTLPDGKEINLGQEAFMCSEVLFDT-SLLERANPGIHMLTLESIMSCE-KSHQRTLFNYIVLTGGTSACTGLRFRMQKEMAKVVSPDFCVKVTASPYAKYSAWIGASILSSLPLFKDMWITNHEYLEIGPSVIFRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9D9L5-1", "uniprot_id": "ACTT2_MOUSE", "id": "Q9D9L5-1", "name": "Actin-related protein T2", "aln": "-----------------------------------------------------------MFNPLVLDSPS-------VIFDNGSGLCKAGLSGEIGPRHVTSSVVGYP-KFKAPPTGASQKKYFVGEEALYKQEALSLHYPIDRGLVTSWDDVEKLWRHLFEWELGVKPCERPVLVTEPSLNPRENREKTAEMMFETFEVPAFYLSDQAVLALYSSACVTGLVVDSGDGVTCTVPIYEGYSLPHAVSKLYVAGKDITELLTRLLLASGRAFPCPLEKALADDIKEKLCYVALEPEEELSRRAED--VLREYKLPDGNVIYIGDQLYQAPEVLFSP-DQLGTHGPGLAQMASNSITKCD-ADIQKTLFGEIVLSGGSTLFQGLDDRLLKELEQLASKGVPIKITAPPDRWFSTWIGASIVTSLSSFKQMWITAADFKEFGVSVVQRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9D9J3-1", "uniprot_id": "ACTT1_MOUSE", "id": "Q9D9J3-1", "name": "Actin-related protein T1", "aln": "-----------------------------------------------------------MLDPARLDNPA-------VIFDNGSGLCKVGISGEIEPRHVINSVVGHP-KFNIPSARSNRKRYFVGEEAQCMYDGLYLHYPIERGLVTRWDDMEKLWKDLFEWELGVKPNEQPVFMTEPSLNPQETREKTTEIMFEKFNVPALYLCNHAVGALCASACITGLVLDSGDGVTCTVPVYEGYSLPHAITKLYVAGRDITEHLTRLLLAKGYTFPCILNKAVVDDIKEKLCTVSLG-YKDTEKNCQQ--FLRKYTLPDGNTIQMSDHLCQVPEVLFTP-DHLGIHDLGISKMVCNSIMNCD-TDIQENLFAEIVLSGGTTMFPGLQDRLLKELEDLAFEGTPIKITASSDRCYSAWIGGSVMTSMTTFKQMWVTAEDFKEYGAFVVQRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BXF8-1", "uniprot_id": "ACTT3_MOUSE", "id": "Q8BXF8-1", "name": "Actin-related protein T3", "aln": "---------------------------------------------------------------MSGYQPP-------VVIDNGSGMIKAGLAGTREPQFVYPNILGRS-KGHTADS---RQELCVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMMLLKGDGIMLLRTGDRKVVTDIKENACYVAMNYEDEMTK---DSNLEKIYTLPDGKTVKLHKQLFHCPEALFSP-YLVNVDAPGIDKMCFGSIMKCD-TDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CG27-1", "uniprot_id": "ACTL9_MOUSE", "id": "Q8CG27-1", "name": "Actin-like protein 9", "aln": "MDVNGHPKFQPS------------------------PETDGPLPLTSSTLMVSKSLQQDSLSMVGDRLPPKTG---AVVIDMGTGTCKVGFAGQSQPTYTVATILGCQ-PKKQATKDQSELETFIGEAARS-RPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSGFSLQQE-DLDLVENIKHHYCYLAPDFQKEQARPDEE--CKQSLKLPDGRTVTLGKELFQCPELLFHPPEIPGLSPIGLPAMAEQSLLKVP-QELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSPEDHVVVMAHPNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * *: * * :* * . :* :* * : *: .* : * : :*. : : . : . :.::..:.. :.: :: **.: **:: :. :: : . .* .:: * *:: **: * * :: ** .:* * :: * : . .:* . . : : ****. : : .. .* :* . *: .: . :: ** *: *: :: : . . ..* *.*:: *: *: *: :: * * : : ", "identical_positions": 49, "similar_positions": 98, "identity": "10.94%" }, { "cls_id": "homologset.agr.FB:FBgn0000047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY84-1", "uniprot_id": "ACL7A_MOUSE", "id": "Q9QY84-1", "name": "Actin-like protein 7A", "aln": "MSLDGVWAPQTANIGDGPAKKASDQASMQTQVLQTASLKDGPAKRAVWVRRDNAETEDPVKSTMSKDRPR-LEVTKAVVVDLGTGFCKCGFAGLPKPTHKISTTVGKPYMETAK-TGDNRKETFVGHELFNPDIHLKLVNPLRHGIIVDWDTVQDIWEYLFRQEMKIAPEEHAVLVSDPPLSPHTNREKYAEMLFETFNTPAMHIAYQSRLSMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTTYLMNLMNNSGKHFSED-HLGIVEDIKTRCCFVALDPIEEKKIPAPE--HEIHYTLPDGKEIRLGQERFLCSEMFFKP-SLIKSMQLGLHTQTVSCLNKCD-IALKRDLMGNILLCGGSTMLRGFPNRLQKELSSMCPNDTP-QVNVLPERDTAVWTGGSILASLQGFQPLWVHRLEYEEHGPFFLYRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QY83-1", "uniprot_id": "ACL7B_MOUSE", "id": "Q9QY83-1", "name": "Actin-like protein 7B", "aln": "MATKNSPSPKPMGTAQGDPGEAG----------------TLPAPEAAGIR--------DTGSTQLKTKPKKIRKIKALVIDLGSQYCKCGYAGEPRPTYFISSTVGKRSAEMAADAGDNFKETYVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKIMPEEHAVLVSDPPLSPTSNREKYAELLFETFGIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPSRVDYAGCDLTNYLMQLLNEAGHKFSDD-HLHIIEHIKKKCCYAALLPEEEMSLGLDE--LHVDYELPDGKIITIGQERFRCSEMLFKP-SLVGCTQPGLPELTATCLARCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSP-TVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "---------------------------------------------------------------MDDDIAA-------LVVDNGSGMCKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETTFNSIMKCD-VDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "---------------------------------------------------------------MDDDIAA-------LVVDNGSGMCKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETTFNSIMKCD-VDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "---------------------------------------------------------------MEEEIAA-------LVIDNGSGMCKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETTFNSIMKCD-VDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83967-1", "uniprot_id": "ACT6_DROME", "id": "P83967-1", "name": "Actin, indirect flight muscle", "aln": "--------------------------------------------------------------MCDDDAGA-------LVIDNGSGMCKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQP-SFLGMESCGIHETVYNSIMKCD-VDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P68134-1", "uniprot_id": "ACTS_MOUSE", "id": "P68134-1", "name": "Actin, alpha skeletal muscle", "aln": "-------------------------------------------------------------MCDEDETTA-------LVCDNGSGLVKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68136-1", "uniprot_id": "ACTS_RAT", "id": "P68136-1", "name": "Actin, alpha skeletal muscle", "aln": "-------------------------------------------------------------MCDEDETTA-------LVCDNGSGLVKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TN73-1", "uniprot_id": "A0AB32TN73_DANRE", "id": "A0AB32TN73-1", "name": "", "aln": "-------------------------------------------------------------MCDDDETTA-------LVCDNGSGLVKAGFAGDDAPRAVFPSIVGR-PRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQP-SFIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "---------------------------------------------------------------MDSEVAA-------LVIDNGSGMCKAGFAGDDAPRAVFPSIVGR-PRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHP-SVLGLESAGIDQTTYNSIMKCD-VDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9D9L5-1", "uniprot_id": "ACTT2_MOUSE", "id": "Q9D9L5-1", "name": "Actin-related protein T2", "aln": "-----------------------------------------------------------MFNPLVLDSPS-------VIFDNGSGLCKAGLSGEIGPRHVTSSVVGY-PKFKAPPTGASQKKYFVGEEALYKQEALSLHYPIDRGLVTSWDDVEKLWRHLFEWELGVKPCERPVLVTEPSLNPRENREKTAEMMFETFEVPAFYLSDQAVLALYSSACVTGLVVDSGDGVTCTVPIYEGYSLPHAVSKLYVAGKDITELLTRLLLASGRAFPCPLEKALADDIKEKLCYVALEPEEELSRRAED--VLREYKLPDGNVIYIGDQLYQAPEVLFSP-DQLGTHGPGLAQMASNSITKCD-ADIQKTLFGEIVLSGGSTLFQGLDDRLLKELEQLASKGVPIKITAPPDRWFSTWIGASIVTSLSSFKQMWITAADFKEFGVSVVQRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9D9J3-1", "uniprot_id": "ACTT1_MOUSE", "id": "Q9D9J3-1", "name": "Actin-related protein T1", "aln": "-----------------------------------------------------------MLDPARLDNPA-------VIFDNGSGLCKVGISGEIEPRHVINSVVGH-PKFNIPSARSNRKRYFVGEEAQCMYDGLYLHYPIERGLVTRWDDMEKLWKDLFEWELGVKPNEQPVFMTEPSLNPQETREKTTEIMFEKFNVPALYLCNHAVGALCASACITGLVLDSGDGVTCTVPVYEGYSLPHAITKLYVAGRDITEHLTRLLLAKGYTFPCILNKAVVDDIKEKLCTVSLG-YKDTEKNCQQ--FLRKYTLPDGNTIQMSDHLCQVPEVLFTP-DHLGIHDLGISKMVCNSIMNCD-TDIQENLFAEIVLSGGTTMFPGLQDRLLKELEDLAFEGTPIKITASSDRCYSAWIGGSVMTSMTTFKQMWVTAEDFKEYGAFVVQRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BXF8-1", "uniprot_id": "ACTT3_MOUSE", "id": "Q8BXF8-1", "name": "Actin-related protein T3", "aln": "---------------------------------------------------------------MSGYQPP-------VVIDNGSGMIKAGLAGTREPQFVYPNILGR-SKG---HTADSRQELCVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMMLLKGDGIMLLRTGDRKVVTDIKENACYVAMN-YEDEMTKDSN--LEKIYTLPDGKTVKLHKQLFHCPEALFSP-YLVNVDAPGIDKMCFGSIMKCD-TDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAE0-1", "uniprot_id": "A0A0G2KAE0_RAT", "id": "A0A0G2KAE0-1", "name": "", "aln": "-----------------------------------------------------------------MDNTP-------IICDYGSGFSKVGFAGTRVPLAVFPTILGK-MKNATLLERLEEEDWFIGAEVQNNRPKLNIHYPIFRGAITNWDNVQKVWHYSFYHYLRIAPEQHPILVTDPPLTTKEARSKMTQILFETFNFPALYLANQGVLSLYASGRTSGTTIESGDGMTYFVPIANGYPLHLSTTKVDTAGQDLTVYLMKLLSDNGNMLETTADLEHVRDLKEKCCYVALDYDMEMSKTSES-SFLKKFTLPDGKEISLGQETFMCPEVLFNP-SLVGKNYPGIDMQAQQSITSCD-KSHWRNLFGYIILSGGTGTCSGLRFRLQREIAKLVSPELSVKVVTSPYAKYGAWVGASILCSLPMFKDMWITNHEYLEIGPSVICRRTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YYH9-1", "uniprot_id": "D3YYH9_MOUSE", "id": "D3YYH9-1", "name": "", "aln": "-----------------------------------------------------------------MEKTP-------LVCDYGSGFSKVGFSGTQAPQAVFPTILGK-MKHTNVLEGLGEQDWFIGAETQTNRTELNMYYPISRGAITNWDNVEKIWHYSFYHSLQIAPEQHPILITEAPLTSKEAKSRMTQILFETFNFPALYTANQAVLSLIASGRTSGTAIESGDGMTYFVPVMNGYPLHLSTTKLDIAGQDLTLYLMKLLSDNGNVLETIADLEYIRDLKDKYSYVALDYNMEMSKTSAP-SFQKKFTLPDGKEINLGQEAFMCSEVLFDT-SLLERANPGIHMLTLESIMSCE-KSHQRTLFNYIVLTGGTSACTGLRFRMQKEMAKVVSPDFCVKVTASPYAKYSAWIGASILSSLPLFKDMWITNHEYLEIGPSVIFRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CG27-1", "uniprot_id": "ACTL9_MOUSE", "id": "Q8CG27-1", "name": "Actin-like protein 9", "aln": "MDVNGHPKFQPS------------------------PETDGPLPLTSSTLMVSKSLQQDSLSMVGDRLPPKTG---AVVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATKDQSE-LETFIGEAARS-RPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSGFSLQQE-DLDLVENIKHHYCYLAPDFQKEQARPDEE--CKQSLKLPDGRTVTLGKELFQCPELLFHPPEIPGLSPIGLPAMAEQSLLKVP-QELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSPEDHVVVMAHPNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *: * * :* * . :* :* * : *: .* : * : :*. : : . : . :.::..:.. :.: :: **.: **:: :. :: : . .* .:: * *:: **: * * :: ** .:* * :: * : . .:* . . : : ****. : : .. .* :* . *: .: . :: ** *: *: :: : . . ..* *.*:: *: *: *: :: * * : : ", "identical_positions": 49, "similar_positions": 97, "identity": "10.94%" }, { "cls_id": "homologset.agr.FB:FBgn0000052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB17-1", "uniprot_id": "D4AB17_RAT", "id": "D4AB17-1", "name": "Phosphoribosylformylglycinamidine synthase", "aln": "MAPVLHFYVRPSGHEGAASGHVLRRLQEKLPTLQNVETELCYNVHWAAETLPWAEEMKKLLWLFGCPLLQ-DDVARESWLVP--------------GSNDLLLEVGPRLNFSTPASTNIVSVCQAAGLR-AVDRVETTRRYRLSFAK--QPTAEMEAISLAALHDRMTEQHYPDP---IQSFSPQSIPAPLKDS----INILAEGRPALEKANQELGLALDSWDLDFYTKRFQ-ELQRNPSTVEVFDLAQSNSEHSRHWFFKGQLHVDGKKLARSLFESIMSTQSSSNPNNVLKFCDNSSAIQGKEVRFLRPEDSTRPSCFRQQRGLRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGYNLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPD----GQRREWIKPIMFSGGIGSMEAKHVGK-EPPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPEMEQKMNRVIRACVEAPGGNPICSLHDQGAGGNGNVLKELSEP--AGAVIYTSRFQLGDPTLNALEIWGAEYQESNALLLRPSDRDFLSRASARERCPACFVGTITGDKRIVLVDDRECLMGKSGQGDAPPTP-PTPVDLDLDWVLGKMPQKEFFLQRKPPVLQPLALPPDLSVGQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSH---QELVGAATALGEQPVKSLLDPKAAARLAVSEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAGLADACEAM-VTVMAALGVAVDGGKDSLSMAARVGTETVPAPGSLVISAYAVCPDITATVTPDLKHPGG--KGHLLYVPLSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFHITQGLLK--DRRLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAP--------------GIHALPVLFAEEPGLVLEVQEADVAGVLQRYQSAGLHCLELGHTGEAGPQAMVRVSVNGTV---VVEEPVGQLRALWEETSFQLDLLQAEPRCVTEEKQGLKERIGPSYCLPPTFPVASVPCK---PGGPIPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAVRLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFNPQAREELGRFR-RRPDTFSLGVCNGCQLLALLGWVGSDPNEDQVEPDHDSQPAQPGLLLRHNLSGRFESRWATVRVE------PGPALMLRGMEGSVLPVWSAHGEGYMAFSS-PELQAKIKAKGLVPLHWADDDGNPTEQYPLNPNGSPGGIAGICSPDGRHLALMPHPERAVRLWQWAWRPSPFDGLST---SPWLQLFINARNWTQEDSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SUR0-1", "uniprot_id": "PUR4_MOUSE", "id": "Q5SUR0-1", "name": "Phosphoribosylformylglycinamidine synthase", "aln": "MAPVLHFYVRPSGHEGAASGRVFRRLQEKLPTLQSVETELCYNVHWAAETLPWAEEMKKLMWLFGCPLVR-DDVAQEPWLVP--------------GSNDLLLEVGPRLNFSTPASTNIVSVCQAAGLR-AVDRVETTRRYRLSFTD--HPTAEMEAISLAALHDRMTEQHYPDP---IQSFSPQSIPAPLKGS----IDILAEGRPALEKANQELGLALDSWDLDFYTKRFQ-ELQRNPSTVEVFDLAQSNSEHSRHWFFKGQLHVDGKKLAHSLFESIMSTQASSNPNNVLKFCDNSSAIQGKKVKFLRPEDSTRPSCFQQQQGLRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPDYNLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPD----GQRREWIKPIMFSGGIGSMEAKHVGK-KPPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPEMEQKMNRVIRACVEAPGGNPICSLHDQGAGGNGNVLKELSDP--EGAIIYTSRFQLGDPTLNALEIWGAEYQESNALLLRPSDRDFLSRASARERCPACFVGTITGDKRIVLVDDRECLVGKTGQGDAPLTP-PTPVDLDLDWVLGKMPQKEFFLQRKPPVLQPLALPPELSVRQALNRVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSH---QECIGAATALGEQPVKSLLDPKAAARLAVSEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADACEAM-VAVMAALGVAVDGGKDSLSMAARVGTETVQAPGSLVISAYAVCPDITATVTPDLKHPGG--KGHLLYVPLSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFHITQGLLK--ECRLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAP--------------GIHALPVLFAEEPGLVLEVQEADVAGVRQRYESAGLRCLELGHTGEAGPQAMARISVNKAV---VVEEPVGELRALWEETSFQLDLLQAEPRCVIEEKQGLKERTGPSYYLPPTFPVASVPCK---PGGPVPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIRLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFNPQAREELGRFR-RRPDTFSLGVCNGCQLLALLGWVGSDPSEEQAEPGQDSQPTQPGLLLRHNLSGRFESRWATVRVE------PGPALMLRGMEGSVLPVWSAHGEGYMAFSS-PELQAKIEAKGLVPLHWADDDGNPTEQYPLNPNGSPGGIAGICSQDGRHLALMPHPERAVRLWQWAWRPSPFDVLPT---SPWLQLFINARNWTQEDSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15067-1", "uniprot_id": "PUR4_HUMAN", "id": "O15067-1", "name": "Phosphoribosylformylglycinamidine synthase", "aln": "MSPVLHFYVRPSGHEGAAPGHTRRKLQGKLPELQGVETELCYNVNWTAEALPSAEETKKLMWLFGCPLLL-DDVARESWLLP--------------GSNDLLLEVGPRLNFSTPTSTNIVSVCRATGLG-PVDRVETTRRYRLSFAH--PPSAEVEAIALATLHDRMTEQHFPHP---IQSFSPESMPEPLNGP----INILGEGRLALEKANQELGLALDSWDLDFYTKRFQ-ELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLHVDGQKLVHSLFESIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQGLRHVVFTAETHNFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGYNLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPD----GQRREWIKPIMFSGGIGSMEADHISK-EAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPEMEQKMNRVIRACVEAPKGNPICSLHDQGAGGNGNVLKELSDP--AGAIIYTSRFQLGDPTLNALEIWGAEYQESNALLLRSPNRDFLTHVSARERCPACFVGTITGDRRIVLVDDRECPVRRNGQGDAPPTPLPTPVDLELEWVLGKMPRKEFFLQRKPPMLQPLALPPGLSVHQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSH---EELIGAATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADACEAM-VAVMAALGVAVDGGKDSLSMAARVGTETVRAPGSLVISAYAVCPDITATVTPDLKHPEG--RGHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLK--DRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVP--------------RVDVLSVLFAEEPGLVLEVQEPDLAQVLKRYRDAGLHCLELGHTGEAGPHAMVRVSVNGAV---VLEEPVGELRALWEETSFQLDRLQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPRE---PGGPSPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAGAELRRFR-KRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNLSGRYESRWASVRVG------PGPALMLRGMEGAVLPVWSAHGEGYVAFSS-PELQAQIEARGLAPLHWADDDGNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLTT---SPWLQLFINARNWTLEGSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35421-1", "uniprot_id": "PUR4_DROME", "id": "P35421-1", "name": "Phosphoribosylformylglycinamidine synthase", "aln": "--MVILRYYDVQAHSAAEEESVLRRLREEDGAVVSVRMERCYHLEYSAQAEHSLALDELLVWLVKQPLSKGQSLSRQPALQST-------------GSSQLLLEIGPRFNFSTPYSTNCVNIFQNLGYS-EVRRMETSTRYLVTFGE--GSKAPEAARFVPLLGDRMTQCLYTEE---NTPKASFDEQLPERQANWHFVPVLEEGRAALERINQELGLAFNDYDLDYYHDLFAKELGRNPTTVELFDCAQSNSEHSRHWFFRGRMVIDGVEQPKSLIRMIMDTQAHTNPNNTIKFSDNSSAMVGFDHQTIVPSSVVAPGAVRLQSVQSDLIFTAETHNMPTAVAPFSGATTGTGGRLRDVQGVGRGGVPIAGTAGYCVGALHIPGYKQPYEPLDFKYPATFAPPLQVLIEASNGASDYGNKFGEPVISGFALSYGLNSAADA--SQRDEYVKPIMFSGGLGTMPATMREK-LPPARGQLLAKIGGPVYRIGVGGGAASSVEIQGSGDAELDFNAVQRGDAEMENKLNRVVRACLDLGEQNPILAIHDQGAGGNGNVLKELVEPGFAGAVIFSKEFQLGDPTITALELWGAEYQENNAILCNADQRELLEKICRRERCPISFVGVVTGDGRVTLLEKP-APKDLEQALNASNRSEVSPFDLELKYVLGDMPKRTYDLKREQTPLKELSLPKGLLLDEALERVLSLVAVGSKRFLTNKVDRCVGGLIAQQQCVGPLQAPLADYALTTVSH---FSHSGIATSIGTQPLKGLLDPAAMARMCVAEALSNLVFVKISELADVKCSGNWMWAAKLPGEGARMFDACKEL-CQILEELHIAIDGGKDSLSMAAKVGGETIKSPGTLVISTYAPCPDVRLKVTPDLKGPGAGSKTSLLWINLEN-SARLGGSALAQAYAQQGKDTPNLTRSDVLGKAFAVTQSLLG--DGLIQAGHDVSDGGLLVCVLEMAIGGLSGLRVDLSEPLAKLKNFDKSVEKLNRPELAVLFAEECGWVVEVLDTDLERVRSTYEKAGVPNYYLGVTEGFGLDSRVVLKNGKSE---LLDQPLRVLYKKWERTSYELEKLQANPECAEAEYNSLEYRQAPQYRGPQNVQAELTLKR---SSAP-VRVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLIFPGGFSYADTLGSAKGWAANILHNPRLLPQFEAFK-RRQDVFSLGICNGCQLMTLIGFVGSAKSEVGAD---------PDVALLHNKSQRFECRWATVKIP------SNRSIMLGSMKDLVLGCWVAHGEGRFAFRD-EKLISHLQSEQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALMPHPERCSSMYQWPYVPSSFEVSPTQSESPWQIMFNNAYNWCVKSNQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38972-1", "uniprot_id": "PUR4_YEAST", "id": "P38972-1", "name": "Phosphoribosylformylglycinamidine synthase", "aln": "--MTDYILPGPKALSQFRVDNLIKDINSYTNSTSVINELRSCYIHYVNGIAQNLSEQDTKLLEVLLTYDSALDIANDPLARQLNDAVANNLPSSALGEDTYLIRVVPRSGTISPWSSKATNIAHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNTMSIFTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLALDSGEMEYLIHAFVETMKRDPTDVELFMFAQVNSEHCRHKIFNADWTIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNAAVLDSENDAFFFAPN-STTKEWTSTKERIPLLIKVETHNHPTAVSPFPGAATGSGGEIRDEGATGRGSKTKCGLSGFSVSDLLIPGNEQPWELN-IGKPYHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTKVLNHQGKEEIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLIVLGGQSMLIGLGGGAASSVAS-GEGSADLDFASVQRGNPEMERRCQQVIDACVALGNNNPIQSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDLSIFEEICKRERAPFAVVGHATAEQKLIVEDPL---------------LKTTPIDLEMPILFGKPPKMSRETITEALNLPEANLSEIPSLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVADVGVTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKLSANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSLNITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPTVYDNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDGGD-------------LESQLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIINSTTNDVIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPADDMKIGLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLAACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDIIPGCEN--------------WPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKATFSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHPERVCRLEANSWYPEGKYEEWG-GYGPWIRLFRSARRWVG----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : :. :. . :.: . : . . .::.:. *.. *:.: ** . :* *:: ..: : * * *:* :. : : ****: : . . . * . : *.: * *****::. :::: . * : *:*: ** * ** ****.** :*.. :** : :*:. * .*: . . :.**::.: . . : . . . :::..**** **.*.**.**:**:**.:** .***. .* :*:... * **. : *:* : * :* .*:: ***. *:: :.*:**.* : *: : : : : ****::**:*:: . * . * : :** **:******** *.. ::*** :****:.***.: ::*: **: *** ::** **** .*.* ** . ** : .. :* :..:*:* * ** .: . : .:: . . ***.* ..** *.: :: : : :*.**:: ::*. *: : * *. : :*::*** * :*.** :* . **.* **: ::* *** *.*:** .:. * * * ::* :*::.*:.. . *::.*:*:* *:. . :..* .:* *.*** .*. ***: : :* : : : * :*: ****:** : . : : :* :* *:::* : . ** *: *: : . **.:** * : * *:..* : * : * : : : ** *****: :****:.. .*:.::: *. ** ** * *.:: :: . . .. *: :. . . .: . : : :. * *..**:::: *: :*. . * .: * . . .. :**:***:* *.: ** .: *.*: **** ** .* :. : *: *****.*.**:. *** : .: :: * .* *.*::* *****::: : : .: : :* * ::*.* . *:: . :::* .* . * ***** :* . : ::: * :::.*: *: ** :*:*****. *:**: * :** **:****** .: * .** :* .* .* ", "identical_positions": 336, "similar_positions": 392, "identity": "23.83%" }, { "cls_id": "homologset.agr.FB:FBgn0000053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V918-1", "uniprot_id": "G3V918_RAT", "id": "G3V918-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLVIGSGGREHTLAWKLAQSPHVKQVLVAPGNAGTASAGKISN----AAVSINDHTALARFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAALLESSKKFAKEFMDRHGVPTAQWRAFTSPEDACSFIMSADFPALVVKASGLAAGKGVIVAKSKAEACEAVQEIMQEKSFG-AAGETVVVEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDRGPNTGGMGAYCPAPQVPKDLLVKIKNTILQRTVDGMQQEGVPYTGILYAGIMLTKDG------PKVLEFNCRFGDPECQVILPLLK--SDLYEVIQSTFDGLLSESPPVWLENHSAVTVVMASGGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDAK--VVTSGGRVLTVTAVRENLMSALDEARKGLAALKFEG--AVYRKDIGFRAVAFLQRPR-GLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFK---DPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVVAGIAAACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMER----------------------------------------------------------------------HQKLPQLER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSG--RVKAFAHITGGGLLENIPRVLPRKLGVDLDAYTWRVPKVFSWLQQEGQLSEEEMARTFNCGVGAALVVSKDQTEQILHDIRQHQEDAWVIGSVVECPE-DSPRVRVKNLIETMQTKGSVVTNGFLRSNFPSQQKKARVAVLISGTGSNLQALIDSTRDPKS--SSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKSRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVQRDDTVATLSERVKAAEHKIFPAALQLVASGAVQLGEDGKIHWAREQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64737-1", "uniprot_id": "PUR2_MOUSE", "id": "Q64737-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLVIGSGGREHTLAWKLAQSPQVKQVLVAPGNAGTACAGKISN----AAVSVNDHSALAQFCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHEIPTAQWRAFTNPEDACSFITSANFPALVVKASGLAAGKGVIVAKSQAEACRAVQEIMQEKSFG-AAGETVVVEEFLEGEEVSCLCFTDGKTVAEMPPAQDHKRLLDGDEGPNTGGMGAYCPAPQVSKDLLVKIKNTILQRAVDGMQQEGAPYTGILYAGIMLTKDG------PKVLEFNCRFGDPECQVILPLLK--SDLYEVMQSTLDGLLSASLPVWLENHSAVTVVMASKGYPGAYTKGVEITGFPEAQALGLQVFHAGTALKDGK--VVTSGGRVLTVTAVQENLMSALAEARKGLAALKFEG--AIYRKDIGFRAVAFLQRPR-GLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLKAAGFK---DPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSTTEAVIAGIAAACQQAGCALLGGETAEMPNMYPPGEYDLAGFAVGAMER----------------------------------------------------------------------HQKLPQLER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGGCGDQTLGDLLLTPTRIYSHSLLPIIRSG--RVKAFAHITGGGLLENIPRVLPQKFGVDLDASTWRVPKVFSWLQQEGELSEEEMARTFNCGIGAALVVSKDQAEQVLHDVRRRQEEAWVIGSVVACPE-DSPRVRVKNLIETIQTNGSLVANGFLKSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKS--SSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAALQLVASGAVQLREDGKIHWAKEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22102-1", "uniprot_id": "PUR2_HUMAN", "id": "P22102-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISN----TAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFG-AAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNG------PKVLEFNCRFGDPECQVILPLLK--SDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGK--VVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEG--AIYRKDVGFRAIAFLQQPR-SLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFK---DPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMER----------------------------------------------------------------------DQKLPHLER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSG--HVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAE-GSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNS--SAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00967-1", "uniprot_id": "PUR2_DROME", "id": "P00967-1", "name": "Trifunctional purine biosynthetic protein adenosine-3", "aln": "MSHRVLVIGSGGREHAICWKLSQSPKVAQIYALPGSHGIQLVEKCRNL-DAKTLDPKDFEAIAKWSKENQIALVVVGPEDPLALGLGDVLQSAGIPCFGPGKQGAQIEADKKWAKDFMLRHGIPTARYESFTDTEKAKAFIRSAPYPALVVKAAGLAAGKGVVVAANAKEACQAVDEILGDLKYG-QAGATLVVEELLEGEEVSVLAFTDGKSVRAMLPAQDHKRLGNGDTGPNTGGMGAYCPCPLISQPALELVQKAVLERAVQGLIKERINYQGVLYAGLMLTRDG------PRVLEFNCRFGDPETQVILPLLE--SDLFDVMEACCSGKLDKIPLQWRNGVSAVGVILASAGYPETSTKGCIISGLPAANTPTQLVFHSGLAVNAQKE-ALTNGGRVLIAIALDGSLKEAAAKATKLAGSISFSGSGAQYRTDIAQKAFKIASASTPGLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVIGGLGGFGGLFRLKELTYK---EPVIAEATQGVGAKIHLALTHELYENVGYDLFALAANDVLEVGAEPVAFLDYIACGKLQVPLAAQLVKGMADGCRDARCALVGGETAEMPSLYAPGQHDMAGYCVGIVEQSRILPRFDLYQPGDLLIGLPSSGLHCAGFNEILTQLAASKVNLRERSPVDGGDDGLTLAHVLATPTQLYVQQLLPHLQKGDEIKSVAHVTHGLLNDILRLLPDGFETTLDFGAVPVPKIFGWLAGKLKLSAQTILERHNCGIGMVLILPQSSQLWRTSLPGAKVLGVLQRRSKVSGSPVQVRNFVEQLEKVASPFGGLGDRELPEELKKLPSNSDLSAPREECFENAAGRRLTRIPTHYKDPILILGTDGVGTKLKIAQQTNRNTSVGIDLVAMCVNDILCNGAEPISFSSYYACGHWQEQLAKEVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYDLAGFALGIAEHTGILPLLDEIQPGDVLIGLPSSGVHSNGFSLVHAVLKRVGLGLHDKAP--FSDKTLGEELLVPTKIYVKALSTLLSRGKHGIKALAHITGGGLSENIPRVLRKDLAVRLDANKFQLPPVFAWLAAAGNISSTELQRTYNCGLGMVLVVAPTEVEDVLKELR-YPQRAAVVGEVVARKDPKKSQVVVQNFEASLARTQKMLS-----------QRRKRVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKTGVLGLQRATQAGIPSLVISHKDFASREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPGLHVQKQALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPRALAMLVNGTALISPEVSSQ-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07244-1", "uniprot_id": "PUR2_YEAST", "id": "P07244-1", "name": "Bifunctional purine biosynthetic protein ADE5,7", "aln": "-MLNILVLGNGAREHVLVTKLAQSPTVGKIYVAPGNGGTATMDPSRVINWDITPDVANFARLQSMAVEHKINLVVPGPELPLVNGITSVFHSVGIPVFGPSVKAAQLEASKAFSKRFMSKHNIPTASYDVFTNPEEAISFLQAHTDKAFVIKADGIAAGKGVIIPSSIDESVQAIKDIMVTKQFGEEAGKQVVIEQFLEGDEISLLTIVDGYSHFNLPVAQDHKRIFDGDKGLNTGGMGAYAPAPVATPSLLKTIDSQIVKPTIDGMRRDGMPFVGVLFTGMILVKDSKTNQLVPEVLEYNVRFGDPETQAVLSLLDDQTDLAQVFLAAAEHRLDSVNIGIDDTRSAVTVVVAAGGYPESYAKGDKITLDTDKLPPHTQIFQAGTKYDSATDSLLTNGGRVLSVTSTAQDLRTAVDTVYEAVKCVHFQN--SYYRKDIAYRAFQNSESSKVAITYADSGVSVDNGNNLVQTIKEMVRSTRRPGADSDIGGFGGLFDLAQAGFRQNEDTLLVGATDGVGTKLIIAQETGIHNTVGIDLVAMNVNDLVVQGAEPLFFLDYFATGALDIQVASDFVSGVANGCIQSGCALVGGETSEMPGMYPPGHYDTNGTAVGAVLR----------------------------------------------------------------------QDILPKINE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGDVLLGLASSGVHSNGFSLVRKIIQHVALPWDAPCP-WDESKTLGEGILEPTKIYVKQLLPSIRQR--LLLGLAHITGGGLVENIPRAIPDHLQARVDMSTWEVPRVFKWFGQAGNVPHDDILRTFNMGVGMVLIVKRENVKAVCDSLTEEGEIIWELGSLQERPK-DAPGCVIEN-------------------------------------GTKLY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*::*.*.***.: **:** * :: . **. * : . :. : . :.:* :** *** **. *: . : *.*: *** :.* :*:.* ::* ** :* :*** : **..*.* :*: : *:*:** *:******::. . *: .*:.:*: :* ** :*:*::*:*:*:* * :.** : : ******: :** * ********.*.* . * :.. ::: :::*: :: : *:*::*::*.::. *.***:* ****** *.:*.**. :** :*: : . * : :*: *::*: *** :** *: . . :*::* . . :* ***** . : .* * . : .: *.. : **.*:. :*. . . .::* :***.: *: **: *: : :.* *.* .:***.*** * :: :.::. .*:***:*: :* ::.:* **.*: .**:: ****: ****:: * *:: : .: *:* .* .: ***:****:***.:*.**.:* * .** : : .: **:::. : **.::*:.***:********: :: : .* .* .:***: :* **:** : * . : : .:******** *****.: .: . :* .:.:* ** *: *.:. :: **:* *:* .*:* :.: : .: : :*.: . . ::* *::* ", "identical_positions": 254, "similar_positions": 266, "identity": "18.33%" }, { "cls_id": "homologset.agr.FB:FBgn0000055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08699-1", "uniprot_id": "PGDH_RAT", "id": "O08699-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "--MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00334-1", "uniprot_id": "ADH_DROME", "id": "P00334-1", "name": "Alcohol dehydrogenase", "aln": "MSFTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIERTIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPIT--GVTAYTVNPGITRTTLVHKFN------SWLDVEPQVAEKLLAHPTQPSLACAENFVKAIELNQ-NGAIWKLDLGT---LEAIQWTKHWDSGI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :..* .:.... *** :: ** :. * :: .:*. . : : *:: .. : . ::.:. :: :*:*:*.**: :::: *:*: :* ..::. * **: .*::** **** **.*::*: .: * ***..:* .::.** * * * : ** .: **:.:*.::..:: .::: *: : : . * *:.::: ** : **** *: .. :: : :... ", "identical_positions": 56, "similar_positions": 106, "identity": "20.9%" }, { "cls_id": "homologset.agr.FB:FBgn0000056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08699-1", "uniprot_id": "PGDH_RAT", "id": "O08699-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQ-KQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPG----FVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPS-AIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15428-1", "uniprot_id": "PGDH_HUMAN", "id": "P15428-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ-QQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPG----FVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPP-LIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91615-1", "uniprot_id": "ADHR_DROME", "id": "P91615-1", "name": "Alcohol dehydrogenase-related 31 kDa protein", "aln": "MFDLTGKHVCYVADCGGIALETSKVLMTKNIAKLAILQSTEN-PQAIAQLQSIKPSTQIFFWTYDVTMAREDMKKYFDEVMVQMDYIDVLINGATLCDENNIDATINTNLTGMMNTVATVLPYMDRKMGGTGGLIVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCGPTRVFVDRELKAFLEYGQSFADRLRRAPCQSTSVCGQNIVNAIERSENGQIWIADKGGLELVKLHWYWHMADQFVHYMQSNDEEDQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:.** . .. . **. ::.*: :. : . * :. * *:. . : :* **: ::::. * :*: ::. :*:*:*.* : :*:* : *:: **..::. . * **.:: ** **:*:*::*: ** * . .*.***.*::***** * . :.** : .:* * **. : :* :.:.: :. . : .*::. ** * : :...*: . :: . :* .* . ", "identical_positions": 60, "similar_positions": 100, "identity": "21.98%" }, { "cls_id": "homologset.agr.FB:FBgn0000061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6YP92-1", "uniprot_id": "ARX_RAT", "id": "A6YP92-1", "name": "Homeobox protein ARX", "aln": "-MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGR-RSPCKMRLLGAAQSLPAPLASRTDQEKAMQGSPK-GSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAG--AVAAAAAAA-WDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVAHPEERLSAASGPGSAPAAGGGTGTEEDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPH-HPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVA-SGALADP----ATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35085-1", "uniprot_id": "ARX_MOUSE", "id": "O35085-1", "name": "Homeobox protein ARX", "aln": "-MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGR-RSPCKMRLLGAAQSLPAPLASRADQEKAMQGSPK-SSSAPFEAELHLPPKLRRLYGPGGGRLLQG-AAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAG--AVAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELSGPGGVAHPEERLSAASGPGSAPAAGGGTGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAA--VATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPH-HPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVA-SGALADP----ATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QS3-1", "uniprot_id": "ARX_HUMAN", "id": "Q96QS3-1", "name": "Homeobox protein ARX", "aln": "-MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGR-RSPCKMRLLGAAQSLPAPLTSRADPEKAVQGSPK-SSSAPFEAELHLPPKLRRLYGPGGGRLLQG--AAAAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVAT-----EGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPH-HPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVA-SGALADP----ATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42115-1", "uniprot_id": "ARXA_DANRE", "id": "O42115-1", "name": "Aristaless-related homeobox protein A", "aln": "-MSSQYDDD-SRDRSECKSKSPTVLSSYCIDSILGR-RSPCKVRQLG-AQSLPAPVRP--DHEMTTEVTSK-ENS--FDSDMHLPPKLRRLYGPGGKYLDSG------------------------RG-----FHEHLEKGERE----------RLLDQACESLKISQAPQVSISRSKSYREN-APFSQS----DE----------------------------GQSPEHMAQELVELSTLKFEEDVVK----EEACGDNS-------------------------------------LSPKDEESLH-NDGDVKDGEDSVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGVQAHPTGLPFPGPLAAAHPLSHYLEGGPFPPHPHPALESAWT-AAAAAAAAFPGLAPPPNSSALPP-ATPLGLGTFLGTAMFRHPAFIGPTFGRLFSSMGPLTSASTAAALLRQTAPPVESPVQPSAALPEPPSSSSSTAADRRASSIAALRLKAKEHSAQLTQLNILPSGTAGKEVC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06453-1", "uniprot_id": "AL_DROME", "id": "Q06453-1", "name": "Homeobox protein aristaless", "aln": "---MGISEEIKLEELPQEAKLAHPDAVVLVDRAPGS-SAASAGAALTVSMSVSGGAPSGASGASGGTNSPVSDGNSDCEADEYAPKRKQRRYRTTFT--------------------------------------------------------SFQLEELEKAFSRTHYPDVFTREELAMKIG-------------------------------------------LTEARIQVWFQNRRAKWRK------------------------------------------------------QEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLA----AFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPASGHASQHQQHP----TAHPPPPQAPPQMPVGVQPAQLSPQHLVGIALTQQASSLSPTQTSPVALTLSHSPQRQLPPPSHQAPPPPPR---AATPPEDRRTSSIAALRLKAREHELKLELLRQNGHGNDVVS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04116-1", "uniprot_id": "YHP1_YEAST", "id": "Q04116-1", "name": "Homeobox protein YHP1", "aln": "MESRNTVLPSLPNIITGTSNSPFQLHTLPNTNFPSDDQGDIRLPPLAASAHIVRPVVNIYKSPCDEERPKRKSPQAVDFLSQRVTTSMTPLSKPKKLSSHSP------------------------------------------------------FTPTVRVCSKEQPPQSMHSYKKVNILT--------------------------------------------PLSAAKAVLTPTTRKEKK--------------------------------------------------------RSFAFITHSQETFPKKEPKIDN-----------ARLARRKRRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGNTSHCK-VHSNDSMSMISYSDAALEITSTPTSTKEAITAELLKTSPANTSSI-------FEDHHITPCKPGGQLKFHRKSVLVKRTLSNTGHSEIIKSPKGKENRLKFNAYERKPLGEVDLNSFKN----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . . * : : . . . . . . . : *: . . : . : .: : : .: : : * : . * *. :. . : : .:. : : : * . : : : .:.. :: . * : : : . . .: . : :.. : ", "identical_positions": 7, "similar_positions": 68, "identity": "1.21%" }, { "cls_id": "homologset.agr.FB:FBgn0000063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2S5-1", "uniprot_id": "A0A0G2K2S5_RAT", "id": "A0A0G2K2S5-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGRNLTIDSIMNKVRDIKNKIN-EDLTDELNSIKVCVDPT---ETVNQIMMVENTPENWLNFLLKLEKNSPPLND-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRLAELKAIQEPDDAH-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAIRNLHLQKKQLLSEEDKKSLSAS---------------------TVLTAQESFSSSLGN-------LQSRKSSCDPKV------------------QAAAARILYGENMPPKDAEVSHRNPLKQTNKTKRSCPFGRVPVNLLN---SPDYY------VKTDGSAVPQFTKRKISGSE------------------------------YRDSIMPG---------------SKSSGNDSY--------ELRGLKP------------------------------------IQAIHLKDSLVSNEKSSELMS-DLVTLKSKTDSS-LTKLEVSEPKVRQEPEIPERRHKQWQSARKPGCGIQ-NSAAFAPQWHVPDVTPK-ADKEQKCTTVEQLAFSVSKQSPPLSVPKWIDPKSVCETPSSSSLDDYMKCFKTSVVKN-EFPPACPSSTPYSQLARHQQHQQQGLSTPLQNLQISGSSSMSECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DRYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENGKIKTKISPRSDVWSLGCILYYMTYGKTPFQHIINQVSKLHAIIDPSHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLAHPYVQIQPHPGSQMAKETTDEMKYMLGQLVCLNSPNSILKAAKTLYERYNCGESQAPSSSKTSDKKRERE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35761-1", "uniprot_id": "TTK_MOUSE", "id": "P35761-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGSSVTIDSIMSKMRDIKNKIN-EDCTDELSLSKICADHT---ETVNQIMRVGNTPENWLNFLLKLEKNSSPLND-DLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQEPDDAR-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAMRNLHLQKKQLLPEEDKKSVSAS---------------------TVLSAQEPFSSSLGN-------VQNRSISCESRG------------------QAGAARVLYGENLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLN---SPDFY------VKTDSSAVTQLTTRLALSSVPLPYVTCLLHLQLLA-----LAGLAKGSGPDRDAILPG---------------SRPRGSDSY--------ELRGLKP------------------------------------IQTIYLKDSLVSNEKSSELMS-DLIALKSKTDSS-LTKLEETKP------EIAERRPMQWQSTRKPECVFQ-NPAAFAPLRHVPDVTPK-ADKE----------------SPPISVPKWLDPKSACETPSSSSLDDYMKCFKTPVVKN-DFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEIT--EQYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAIINPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATDEMKYVLGQLVGLNSPNSILKTAKTLYERYNCGEGQDSSSSKTFDKKRERK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33981-1", "uniprot_id": "TTK_HUMAN", "id": "P33981-1", "name": "Dual specificity protein kinase TTK", "aln": "MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSD-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDAR-DYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSAS---------------------TVLTAQESFSGSLGH-------LQNRNNSCDSRG------------------QTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLN---SPDCD------VKTDDSVVPCFMKRQTSRSE------------------------------CRDLVVPG---------------SKPSGNDSC--------ELRNLKS------------------------------------VQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQ--EPEVPESNQKQWQSKRKSECINQ-NPAASSNHWQIPELARK-VNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKN-DFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DQYIYMVMECGNIDLNSWLKKKKS--IDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSS----RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AYG3-1", "uniprot_id": "TTK_DANRE", "id": "Q8AYG3-1", "name": "Dual specificity protein kinase Ttk", "aln": "MDEEESTERQMQIAMLCQKLAMMKQLFN-EDDTDYIN-----------------QAISSNSPDTCRTFLSNLEKKGNPQADPSLLSKLMDSYTRVFSSMPLGKYSQNESYAKMLVRFAELKAIQDVNDAQ-TSFDIARSHCKDFAFVHVAYAQFELLQGNMKKCTMILQKAFEMNAKPRHVLEAAVRNLKTGKRQLLSHEDKENLSVSALDHTQGSRRSDGTCELKPSNTFLHSDQKFSPQEENGPVWRTGSQHRRTAMAERVPMVPLSIPENETSDSDCAQKAEAPFTHSSGFSRQTSGSSVRSAFSLCSSKKGTPDGDSYSLNIKPPVISPDYLREDIEEGHTITALLNRAEKRETARTEETTDINQIISTNSTEGCQAFLKNLEKRADPHSDAAFLSKLLDCYSKVFARFPLAEHCKTESYARMLVRYAELKGIEDPEDAADDFSIARSHCKAFAFVHIAHAQFELSRGNSRKSVSILQKALSSNARPIELLQTAIRNLKSGKTLLLPAEHQESSEAEN--VEAQNGMKREENPVKAPEDHQKPFSKETSSEWKIPALITKHTSPEDRKAPVEPVSSSSSHHAVRTPAPLRLNPSLSCQTPNYRQPNP--NSFVTPVVKQRPVIVSVPATAQKMCPTALPCTPQSGVSYIQPPTQTPSSAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEIT--SSYIYMLMECGHLDLNTWLRNRKT--VKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGSLKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSS-------NGKPGSKISAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSPNSIARAASNLAMMCNSGRKLDVSECVKSSSQTLWK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG66-1", "uniprot_id": "A0A0B4KG66_DROME", "id": "A0A0B4KG66-1", "name": "", "aln": "----------MTTPVPRRTKDMMALGLD------------------------------SDSEDDFNTPYRPRQAAAGERKQQPVASFQVQTRGKENEPHPLP-------INMLPRRVSELTMMDSDSDEE-DIKSNHNLNCAILNDSFVLSPSQELTNSNSN-----ITTRRTPSAAPLKQSDSNLSFLGRFNDMGINCSSQGSPVAN-------------------------SEKQVAKKTAP--------------------------------------TLQAAPSATERRPLQETETPLRNELPSTSKTKPDADFITPQVRTIG-------------------------------------------------------------------STLAG-------------------------------------------------------------------------------KSRSAVSNDFRAQKVLFQTPMTVSRAAPVA-----------------------------------------SDSISFSLCDTITE---------------------SPDIPEPPKKAEPPKSQHPSKKSLDH---VFRESDKDN------VPDKVDNVEPKELVSIPAVAVPPEQPSHKTSN------ILKIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGN-VCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTN-LPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPP-----YYPIMLVHFTTVSALFADGQELPTVESQKAAVVHRTTTVPIPYDHSAAEPADTQQNRQQQLSTKAQLFISEMSKVKCLSHMCVYIFNSHFIVN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54199-1", "uniprot_id": "MPS1_YEAST", "id": "P54199-1", "name": "Serine/threonine-protein kinase MPS1", "aln": "------MSTNSFHDYVDLKSRTNTRQFS------------------------------DDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAER---RSKRFLISNRTTKLGPAKR---------------------AMTLTNIFDEDVPN---------------------------------------SPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLP-------TSDLPLISQIYFDKQREEN-------------------------------RQAALRKHS------------------------------------------------------------------------SRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSS--------SSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISR-------------------NKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQ-KRVIQLLDYEMG--DGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQN-RLLAIMNPDVKIPFPEHTSNN---------EKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . : . ..:*. . . . : : .. *: .* . . : : .. : . . :. : . :. . . .. . ::: :. : : . : : . . . : :.::. : : :* **** *: . . * * . ::.: .* * :*: :: * **:: . :*::** *. **. *.. . : :** .:: :*. *::*********::*.* **:******. : . ..: : :* ** **:.***: . *:. .*:** ***:* : * :.*: : . :: ** * .* :* . : . : . : : : : . . . : ", "identical_positions": 70, "similar_positions": 140, "identity": "6.88%" }, { "cls_id": "homologset.agr.FB:FBgn0000064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05065-1", "uniprot_id": "ALDOA_RAT", "id": "P05065-1", "name": "Fructose-bisphosphate aldolase A", "aln": "MPHPYPALTPEQKKELADIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05064-1", "uniprot_id": "ALDOA_MOUSE", "id": "P05064-1", "name": "Fructose-bisphosphate aldolase A", "aln": "MPHPYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04075-1", "uniprot_id": "ALDOA_HUMAN", "id": "P04075-1", "name": "Fructose-bisphosphate aldolase A", "aln": "MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JH70-1", "uniprot_id": "ALDCB_DANRE", "id": "Q8JH70-1", "name": "Fructose-bisphosphate aldolase C-B", "aln": "MTHQYPALTAEQKKELQDIAQRIVAPGKGILAADESTGSMAKRLNPIGVENTEENRRLYRQLLFSADERIDKCIGGVIFFHETLYQNTDDGTNFAQLIKDRGIVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRSVLKISDTTPSELAIMENANVLARYASICQQNGIVPIVEPEILPDGEHDLKRCQYVTEKVLAACYKALSDHHVYLEGTLLKPNMVTAGHSCPTKYSSEEIAMATVTALRRTVPPAVSGVTFLSGGQSEEEASVNLNSINNCPLAKPWPLTFSYGRALQASALSAWRGAKSNEKAATEEFIKRAEANGLAAQGKYVSSG-TCGAAGQSLYVANHAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4KMC8-1", "uniprot_id": "ALDCA_DANRE", "id": "Q4KMC8-1", "name": "Fructose-bisphosphate aldolase C-A", "aln": "MTHQFPPLTTEQKKELHEIALRIVSPGKGILAADESIGSMGKRLNQIGVENNEENRRLFRQVLFTADDRIDNCIGGVIFFHETLYQNSDDGVPFVKMIKDKGITIGIKVDKGVVPLPGTNGETATQGLDGLSERCAQYKKDGADFAKWRCVMKISETTPSNLCITENAKVLARYASICQQHGIVPIVEPEILPDGDHNLKRCQFVTERVLAAVYKAMFDHHVYLEGTLLKPNMVTPGHGCPTKYSAEEVAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLSAINNCRLVKPWALTFSFGRALQASALKTWRGQRENEAAATEEFIKRAEINSLASQGKYTVCGDSSGATGLSHYLSSYAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09117-1", "uniprot_id": "ALDOC_RAT", "id": "P09117-1", "name": "Fructose-bisphosphate aldolase C", "aln": "MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQEKGILVGIKVDKGVVPLAGTDGETTTQGLDGLLERCAQYKKDGADFAKWRCVLKISDRTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQFVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCSLPRPWALTFSYGRALQASALSAWRGQRDNAGAATEEFIKRAEMNGLAAQGKYEGSG-DGGAAAQSLYVANHAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05063-1", "uniprot_id": "ALDOC_MOUSE", "id": "P05063-1", "name": "Fructose-bisphosphate aldolase C", "aln": "MPHSYPALSAEQKKELSDIALRIVTPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGILVGIKVDKGVVPLAGTDGETTTQGLDGLLERCAQYKKDGADFAKWRCVLKISDRTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQRDNAGAATEEFIKRAEMNGLAAQGRYEGSG-DGGAAAQSLYIANHAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09972-1", "uniprot_id": "ALDOC_HUMAN", "id": "P09972-1", "name": "Fructose-bisphosphate aldolase C", "aln": "MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYTPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASFNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQRDNAGAATEEFIKRAEVNGLAAQGKYEGSGEDGGAAAQSLYIANHAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07764-1", "uniprot_id": "ALF_DROME", "id": "P07764-1", "name": "Fructose-bisphosphate aldolase", "aln": "MTTYFNYPSKELQDELREIAQKIVAPGKGILAADESGPTMGKRLQDIGVENTEDNRRAYRQLLFSTDPKLAENISGVILFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSEDEVTTQGLDDLAARCAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPIVEPEVLPDGDHDLDRAQKVTETVLAAVYKALSDHHVYLEGTLLKPNMVTAGQS-AKKNTPEEIALATVQALRRTVPAAVTGVTFLSGGQSEEEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAWAGKKENIAAGQNELLKRAKANGDAAQGKYVAGS--AGAGSGSLFVANHAY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00884-1", "uniprot_id": "ALDOB_RAT", "id": "P00884-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MAHRFPALTSEQKKELSEIAQRIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFRELLFSVDNSISQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRISDQCPSSLAIQENANALARYASICQQNGLVPIVEPEVLPDGDHDLEHCQYVSEKVLAAVYKALNDHHVYLEGTLLKPNMLTAGHACTKKYTPEQVAMATVTALHRTVPAAVPSICFLSGGMSEEDATLNLNAIYRCPLPRPWKLSFSYGRALQASALAAWGGKAANKKATQEAFMKRAVANCQAAQGQYVHTGSSGAASTQSLFTASYTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Y97-1", "uniprot_id": "ALDOB_MOUSE", "id": "Q91Y97-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MAHRFPALTPEQKKELSEIAQRIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFRELLFSVDNSISQSIGGVILFHETLYQKDSQGNLFRNVLKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVLPDGDHDLEHCQYVSEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINRCPLPRPWKLSFSYGRALQASALAAWGGKAANKKATQEAFMKRAMANCQAAQGQYVHTGSSGAAATQSLFTASYTY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05062-1", "uniprot_id": "ALDOB_HUMAN", "id": "P05062-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MAHRFPALTQEQKKELSEIAQSIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAANKEATQEAFMKRAMANCQAAKGQYVHTGSSGAASTQSLFTACYTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JH71-1", "uniprot_id": "ALDOB_DANRE", "id": "Q8JH71-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MTHQFPALSTEQKKELATIAERIVAPGKGILAADESTGTMAKRFQKINVENTEENRRSFRDLLFSVDDSISESIGGVILFHETLYQKSDKGVLFPKVIKDKGIVVGIKVDKGTAGLAGTDGETTTQGLDGLSERCAQYKKDGCDFAKWRCVLKISDSCPSALGIAENANVLARYASICQQNGLVPIVEPEILPDGDHDLKQCQYATEKVLAAVYKALSDHHVYLEGTLLKPNMVTAGHSCTKKYTPLEVAMATVTALRRTVPAAVPGICFLSGGQSEEEASLNLNAMNQLSLHRPWKLSFSYGRALQASALSAWKGQAANKKASQDAFVTRAKINSLASKGEYKPSGQAGQASTQSLFTASYTY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : * :.** ** **: ********** ::.:*:. * .**.*:*** :*::*::.* : *.***:*******: ..* * . ::.:* :***:*:* . * *:: *.: ****.* ********* **.***.*::*.. ** * ***:.*********.: :*******::***:*:*.:.* .:* **** ***: ***:***********:*.*:. . * : ::*:*** **:****.**..: ***** ***:*:.**.:: * :** *:**:*******.* :* * * * : :.** * *.:*.* . * * : : ::*", "identical_positions": 175, "similar_positions": 99, "identity": "48.08%" }, { "cls_id": "homologset.agr.FB:FBgn0000071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z3B1-1", "uniprot_id": "NEGR1_HUMAN", "id": "Q7Z3B1-1", "name": "Neuronal growth regulator 1", "aln": "MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAG-QSVDFPWAAVDNMMVRKGDTAVLRCY--LEDGASKGAWLNRSSIIFAGGDKWSVDPRVSIST--LNKRDYSLQIQNVDVTDDGPYTCSVQT-QHTPRTMQVHLTVQVPPKIYD-ISNDMTVNEGTNVTLTCLATGKPEPSISWR--HISPS--AKPFENGQYLDIYGITRDQAGEYECSAENDV-SFPDVRKVKVVVNFAPTIQEIKS-GTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNG-QQGIIIQNFS---TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNP---PST-----------AQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3I9-1", "uniprot_id": "A0A8M3B3I9_DANRE", "id": "A0A8M3B3I9-1", "name": "Neuronal growth regulator 1", "aln": "MDIMIAVQDACVSGQWLTAIILSLCCFLPSCLPAG-QTVDYTTSSES-VVSRQGDTALLRCY--LLDGISKGAWLNRSSIIYAGNDKWSGDPRVSIVSNVGDKHEYSLQIQKVDVTDEGVYTCSIQS-ERNLHPKLIQLIVKVPPKIYD-ISSDITVNEGSNVSLICAASGKPEPKISWR--HISPS--ARKYESGEYLNITGISRDQAGDYECGAENDI-ASPDTKTVRVTVNFPPAIHEMKS-HGVRPGQVALLRCEAAAVPSPVFEWYKGEKRINMG--QGIVINNLS---SRSVLTVKNMTQDRYGNYTCVAVNRLGTANASVPLNPIIEPTTTSAVSSPASNPAMYGSTGGAEVLLACWYLILALSSLVTVY--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32736-1", "uniprot_id": "OPCM_RAT", "id": "P32736-1", "name": "Opioid-binding protein/cell adhesion molecule", "aln": "---MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDN-VTVRQGESATLRCT--IDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVN--TPTQYSIMIQNVDVYDEGPYTCSVQT-DNHPKTSRVHLIVQVPPQIMN-ISSDITVNEISSVTLLCLAIGRPEPTVTWR--HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-AAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATG-LDGVRIENKG---RISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYG---PGA------------VIDGVNSASRALACLWLSGTFFAHFFIKF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8G3-1", "uniprot_id": "G5E8G3_MOUSE", "id": "G5E8G3-1", "name": "", "aln": "---MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDN-VTVRQGESATLRCT--IDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVN--TPTQYSIMIQNVDVYDEGPYTCSVQT-DNHPKTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLLCLAIGRPEPTVTWR--HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-AAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATG-LDGVRIENKG---RISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYG---PGA------------VIDGVNSASRALACLWLSGTFFAHFFIKF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14982-1", "uniprot_id": "OPCM_HUMAN", "id": "Q14982-1", "name": "Opioid-binding protein/cell adhesion molecule", "aln": "---MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDN-VTVRQGESATLRCT--IDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVN--TPTQYSIMIQNVDVYDEGPYTCSVQT-DNHPKTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLLCLAIGRPEPTVTWR--HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-AAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG-LDGMRIENKG---RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYG---PGA------------VIDGVNSASRALACLWLSGTLLAHFFIKF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62718-1", "uniprot_id": "NTRI_RAT", "id": "Q62718-1", "name": "Neurotrimin", "aln": "---MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDN-VTVRQGESATLRCT--IDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSN--TQTQYSIEIQNVDVYDEGPYTCSVQT-DNHPKTSRVHLIVQVSPKIVE-ISSDISINEGNNISLTCIATGRPEPTVTWR--HISPK-AVGFVSEDEYLEIQGITREQSGEYECSASNDV-AAPVVRRVNVTVNYPPYISEAKG-TGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEG-KKGVKVENRP---FLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFG---PGA------------VSEVNNGTSRRAGCIWLLPLLVLHLLLKF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PJ0-1", "uniprot_id": "NTRI_MOUSE", "id": "Q99PJ0-1", "name": "Neurotrimin", "aln": "---MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDN-VTVRQGESATLRCT--IDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSN--TQTQYSIEIQNVDVYDEGPYTCSVQT-DNHPKTSRVHLIVQVSPKIVE-ISSDISINEGNNISLTCIATGRPEPTVTWR--HISPK-AVGFVSEDEYLEIQGITREQSGEYECSASNDV-AAPVVRRVKVTVNYPPYISEAKG-TGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEG-KKGVKVENRP---FLSKLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFG---PGA------------VSEVNNGTSRRAGCIWLLPLLVLHLLLKF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P121-1", "uniprot_id": "NTRI_HUMAN", "id": "Q9P121-1", "name": "Neurotrimin", "aln": "---MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDN-VTVRQGESATLRCT--IDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSN--TQTQYSIEIQNVDVYDEGPYTCSVQT-DNHPKTSRVHLIVQVSPKIVE-ISSDISINEGNNISLTCIATGRPEPTVTWR--HISPK-AVGFVSEDEYLEIQGITREQSGDYECSASNDV-AAPVVRRVKVTVNYPPYISEAKG-TGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEG-KKGVKVENRP---FLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFG---PGA------------VSEVSNGTSRRAGCVWLLPLLVLHLLLKF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NGN9-1", "uniprot_id": "IGLO5_HUMAN", "id": "A6NGN9-1", "name": "IgLON family member 5", "aln": "-----MPPPAPGARLRLLAAA-ALAGLAVISRGLLSQSLEFNSPADN-YTVCEGDNATLSCF--IDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLIN--TPEEFSILITEVGLGDEGLYTCSFQT-RHQPYTTQVYLIVHVPARIVN-ISSPVTVNEGGNVNLLCLAVGRPEPTVTWR--QLRDG----FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTER---TRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLR---PGS------------LEN---SAPRPPGLLALLSALGWLWWRM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8HW98-1", "uniprot_id": "IGLO5_MOUSE", "id": "Q8HW98-1", "name": "IgLON family member 5", "aln": "-----MPPPAPGARLRLLAAA-ALAGLAVISRGLLSQSLEFSSPADN-YTVCEGDNATLSCF--IDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLIN--TPEEFSILITQVGLGDEGLYTCSFQT-RHQPYTTQVYLIVHVPARIVN-ISSPVAVNEGGNVNLLCLAVGRPEPTVTWR--QLRDG----FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGSAEGLKVQTER---TRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLR---PGS------------LEN---SAPRPPGPLTLLSALSWLWWRM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LA63-1", "uniprot_id": "A0ABK0LA63_RAT", "id": "A0ABK0LA63-1", "name": "", "aln": "-----LWTNAVWP-LRLSASGRQLTSTTDLLPGLLSQSLEFSSPADN-YTVCEGDNATLSCF--IDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLIN--TPEEFSILITQVGLGDEGLYTCSFQT-RHQPYTTQVYLIVHVPARIVN-ISSPVAVNEGGNVNLLCLAVGRPEPTVTWR--QLRDG----FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGSAEGLKVQTER---TRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLR---PGS------------LEN---SAPRPPGPLTLLSALSWLWWRM--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15364-1", "uniprot_id": "AMAL_DROME", "id": "P15364-1", "name": "Protein amalgam", "aln": "---MARLRLLIGLIFCLAISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTG---SAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGE-GQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQ-------------------------------TVIPVPSLS--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : : : :. . *. .*: .::: ::: * :: : * * * *.. . : * ::... * : .. :.* .: * * * * *:*.::* : * * .: * : * * * : *. . * : : : *:: * * .: . : *. . * . . *.* : . . : * * . .: :*:* * * *:** :.* : * : ", "identical_positions": 44, "similar_positions": 76, "identity": "11.43%" }, { "cls_id": "homologset.agr.FB:FBgn0000075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14173-1", "uniprot_id": "DDC_RAT", "id": "P14173-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRALIPTTAPQEPETYEDIIRDIEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKMIRQLQAASPELTQAALMEKLVAYTSDQAHSSVERAGLIGGVKIKAIPSDGNYSMRAAALREALERDKAAGLIPFFVVVTLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTEAFNMDPVYLRHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVKLSHEFESLVRQDPRFEICTEVILGLVCFRLKGSNQLNETLLQRINSAKKIHLVPCRLRDKFVLRFAVCSRTVESAHVQLAWEHIR----DLASSVLRAEKE--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88533-1", "uniprot_id": "DDC_MOUSE", "id": "O88533-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRPLIPATAPQEPETYEDIIKDIEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKVIRQLQAASPEFTQAAIMEKLVAYTSDQAHSSVERAGLIGGIKLKAVPSDGNFSMRASALREALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRTDLTGAFNMDPVYLKHSHQDSGFITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVELSHEFESLVRQDPRFEICTEVILGLVCFRLKGSNELNETLLQRINSAKKIHLVPCRLRDKFVLRFAVCARTVESAHVQLAWEHIS----DLASSVLRAEKE--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20711-1", "uniprot_id": "DDC_HUMAN", "id": "P20711-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIK----ELAADVLRAERE--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18486-1", "uniprot_id": "DHAPP_DROME", "id": "P18486-1", "name": "3,4-dihydroxyphenylacetaldehyde synthase", "aln": "MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMDTKASDIDFAWQEIESQLTDLQAEQSLVARKSGNVGDLAQHFQIHLSTENATHEKSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ***. ** :**:*:*::.*.. * *:****** *:*: *:**::::*:: *:.::* **:***:**::.**:**::***:::.:**...:* ***** .********.*:****.*:*:** * * ************.***:**** : : . : : **:::: : :****:***::*.:*:**::..: :: :*:. :: :*. :*: *:*.* *** **.: *.***** *::*:: .:..:*:: :***:******.** * * :*:: .**:*** **::**********:: ..:. :*.:* **:*.*:... *.*:************:**:*:.** *.:**: ::***::*:::**.** :*.***: . ******* **.*::. ****: . ***::* .. .: .***.:*. .:::.:: **:.* :* :. . :: ", "identical_positions": 217, "similar_positions": 176, "identity": "42.55%" }, { "cls_id": "homologset.agr.FB:FBgn0000077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACD9-1", "uniprot_id": "A0A8I6ACD9_RAT", "id": "A0A8I6ACD9-1", "name": "TM2 domain-containing protein 3", "aln": "----MEAAAEPLRSVRHLSRVLLFLSQCYILSGDGSLNLDHSQPLAQSIKDPGPT--------------RIFIVVPRAAENQLFSHLTESTEIPPYMMKCPSNG------------LCSRLPADCIECATNASCTYGKPVTFDCTVKPSVTCVDQDLRPQRNFVINMTCRFCWQLPETDYECSNSTTCMTVACPRQRYFANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ83-1", "uniprot_id": "TM2D3_MOUSE", "id": "Q8BJ83-1", "name": "TM2 domain-containing protein 3", "aln": "----MEAAAEPLRSVRHLSRVLLFLSQCYILSGDGSLNLEHSQPLAQAIKDPGPT--------------RTFSVVPRAAENQLFSHLTESTEIPPYMTKCPSNG------------LCSRLPADCIECATNVSCTYGKPVTFDCTVKPSVTCVDQDLKPQRNFVINMTCRFCWQLPETDYECSNSTTCMTVACPRQRYFANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRN9-1", "uniprot_id": "TM2D3_HUMAN", "id": "Q9BRN9-1", "name": "TM2 domain-containing protein 3", "aln": "----MAGGVLPLRGLRALCRVLLFLSQFCILSGG-----EQSQALAQSIKDPGPT--------------RTFTVVPRAAE---------STEIPPYVMKCPSNG------------LCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PLF5-1", "uniprot_id": "TM2D3_DANRE", "id": "A5PLF5-1", "name": "TM2 domain-containing protein 3", "aln": "-----------MSSYIMLVLLLLDIYSSCVDGYLSSPHVGQDPPYLAQQKSVMSS--------------PVALTASSASP----------VVTDNYVSKCPSGG------------LCSKLPADCIICALHHNCSYGRPHNYTCRPRAGVHCVSDQGERQQNFTLSLLCRFCFQLDASQYRCSNSSDCMTVSCPRRRYNASCEVLEHVHCLGKRVFQKRLFCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U4H5-1", "uniprot_id": "TM2D3_DROME", "id": "Q9U4H5-1", "name": "TM2 domain-containing protein almondex", "aln": "MRLQRQCIVVNMRSAIVLIMIFVLTGIRNSETASGGNQMDLSDSKGDHKDNSNASNGNGNANDNEVYVPPLVSSMVAKSGGGAGGLLDNITAYSSSSSSSSSNGNNNMLCPYDKETPCDRLQFPCIRCNYNHGCIYGRDLNVTCEVINNVQCLGE-----RSFQRQMNCRYCYQTEMWQQSCGQRSSCN--SATDKLFRTNCTVHHDVLCLGNRSFTRNLRCNWTQGYRWSTALLISLTLGGFGADRFYLGHWQEGIGKLFSFGGLGVWTIIDVLLISMHYLGPADGSLYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * ::: . . .. .: : . ...*.* *.:* ** * : .* **: . * .* *:.: :.* .: **:*:* : * : : * :.. : : :.* * ..: ***:* * : * **** **:***** :*:*************:*:**:**********:**:******.: *:*********", "identical_positions": 85, "similar_positions": 59, "identity": "29.21%" }, { "cls_id": "homologset.agr.FB:FBgn0000078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY75-1", "uniprot_id": "A0A8I5ZY75_RAT", "id": "A0A8I5ZY75-1", "name": "Alpha-amylase", "aln": "MTLPLHFSLQRHLTREYCQHHSRMKFFLLLSLIGLCWAQYDPHTFYGRSSIVHLFEWRWVDIAKECERYLAPNGFGGVQVSPPNENIVVNSPFRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAEAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCKTGSGGIENYNDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAVLDKLHNLNTKW-FSEGSKPFIYQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVLRKWDGEKMAYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGSSILTFWDARLYKMAVGFMLAHPYGFTRVMSSFHWPRYFENGKDVNDWVGPP-NNNGATKEVTINSDSTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFGRGNKGFIVFNNDDWDLSTTLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGSDGNAYFSISNSAEDPFIAIHVESKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00687-1", "uniprot_id": "AMY1_MOUSE", "id": "P00687-1", "name": "Alpha-amylase 1", "aln": "-----------------------MKFFLLLSLIGFCWAQYDPHTQYGRTAIVHLFEWRWVDIAKECERYLAPNGFAGVQVSPPNENIVVHSPSRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAQAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCRTASGGIENYQDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVMRKWDGEKMSYLKNWGEGWGLMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYYWPRNFQNGKDVNDWVGPP-NNNGKTKEVSINPDSTCGNDWICEHRWRQIRNMVAFRNVVNGQPFANWWDNDSNQVAFGRGNKGFIVFNNDDWALSETLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGNDGKAHFSISNSAEDPFIAIHAESKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2M0-1", "uniprot_id": "A0ABK0M2M0_RAT", "id": "A0ABK0M2M0-1", "name": "Alpha-amylase", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWDFNDNKCN---GEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKFGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWTRNFQNGKDVNDWIGPP-NNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LP04-1", "uniprot_id": "A0ABK0LP04_RAT", "id": "A0ABK0LP04-1", "name": "Alpha-amylase", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFAGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWDFNDNKCN---GEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKFGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWTRNFQNGKDVNDWIGPP-NNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00689-1", "uniprot_id": "AMYP_RAT", "id": "P00689-1", "name": "Pancreatic alpha-amylase", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCN---GEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPP-NNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00688-1", "uniprot_id": "AM2A5_MOUSE", "id": "P00688-1", "name": "Pancreatic alpha-amylase 2a5", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNENVVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCGAGNPAGTSSTCGSYLNPNNREFPAVPYSAWDFNDNKCN---GEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGLVPSDRALVFVDNHDNQRGHGAGGSSILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWNRNFQNGKDQNDWIGPP-NNNGVTKEVTINADTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWALSATLQTGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DTE7-1", "uniprot_id": "AMY1B_HUMAN", "id": "P0DTE7-1", "name": "Alpha-amylase 1B", "aln": "-----------------------MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNW-FPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPP-NDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DTE8-1", "uniprot_id": "AMY1C_HUMAN", "id": "P0DTE8-1", "name": "Alpha-amylase 1C", "aln": "-----------------------MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNW-FPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPP-NDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DUB6-1", "uniprot_id": "AMY1A_HUMAN", "id": "P0DUB6-1", "name": "Alpha-amylase 1A", "aln": "-----------------------MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNW-FPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPP-NDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04746-1", "uniprot_id": "AMYP_HUMAN", "id": "P04746-1", "name": "Pancreatic alpha-amylase", "aln": "-----------------------MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNW-FPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPP-NNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19961-1", "uniprot_id": "AMY2B_HUMAN", "id": "P19961-1", "name": "Alpha-amylase 2B", "aln": "-----------------------MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMSGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLVGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNW-FPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPP-NNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TC54-1", "uniprot_id": "A0AB32TC54_DANRE", "id": "A0AB32TC54-1", "name": "Alpha-amylase", "aln": "------------------MRKGTMKLLVVAALVGLCLSQHNTNFKHNRTSIVHLFEWRWADIAKECERYLAPNGYGGVQISPPSESIVLTKPWHPWWQRYQPISYNLCSRSGTEEELKDMIARCNNVGVNIYADAVINHMCGASGGEGTHSSCGTYFNAKNEDFPSVPYSSWDFNDNKCKTANEDIENYSDIFQVRDCRLVSLLDLALEKDYVRGKVAEYMNKLIDIGVAGFRVDACKHMWPGDLSNVYSRLKTLNTTW-FSPGTKPFIYQEVIDLGGEPIKASEYVSLGRVTEFKYSAKLGTVIRKWEKEKLCYLKNWGEGWGFMPSHKALVFVDNHDNQRGHGAGGASVLTFWDSRLYKIATGLMLAHPYGVTAVMSSYRWDRHFVNGKDQNDWMGPPSNADGSTKSVPINPDSTCGDNWICEHRWRQIRNMVIFRNVVNGQPLSNWWDNNNNQIAFSRGSKGFIVINNDDWDLNVTLKTGLPSGTYCDIISGDKSGNSCTGKQVTVDSDGQATFSICHTEEDPFMAIHADSKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P81641-1", "uniprot_id": "AMYB_DROME", "id": "P81641-1", "name": "Alpha-amylase B", "aln": "--------------------MFLAKSIVCLSLLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDS--RPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADG---GTYGTGGSTASPSSKSYPGVPYSSLDFNP------TCAISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKVFR--GKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQ---------GPPTTDGHNIASPIFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGLDEIQNWWDSGSNQISFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRASIYIGSSEDDGVLAIHVNAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :... :*...: .*:.:******:* *** ***.:*.*:*:.***:** .*. . :***:****:**:: :***.*::: .*: *** ***. *.*.*:***.. . * .: *: .. ...:..****. ** *.**.* :**:*.* .* ** :.**: *:.:::::***:******:**.*****.*: : .:*:.**: *. *::.:* *****:***.:. .:* . * :***:.. .:*.*:* ::: **.*** .**: .:.::*****************:.:**: .: **:* .:*****:* . ****: *** . . . :*.*.:*...*:******** *** ***.*. : : **:*...**::*.**.:**:.:***:: :. :*:****:*****:***.* ...*** : *..**.* : * : :* .:***.::*:", "identical_positions": 213, "similar_positions": 178, "identity": "39.74%" }, { "cls_id": "homologset.agr.FB:FBgn0000079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY75-1", "uniprot_id": "A0A8I5ZY75_RAT", "id": "A0A8I5ZY75-1", "name": "Alpha-amylase", "aln": "MTLPLHFSLQRHLTREYCQHHSRMKFFLLLSLIGLCWAQYDPHTFYGRSSIVHLFEWRWVDIAKECERYLAPNGFGGVQVSPPNENIVVNSPFRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAEAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCKTGSGGIENYNDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAVLDKLHNLNTKW-FSEGSKPFIYQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVLRKWDGEKMAYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGSSILTFWDARLYKMAVGFMLAHPYGFTRVMSSFHWPRYFENGKDVNDWVGPP-NNNGATKEVTINSDSTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFGRGNKGFIVFNNDDWDLSTTLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGSDGNAYFSISNSAEDPFIAIHVESKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00687-1", "uniprot_id": "AMY1_MOUSE", "id": "P00687-1", "name": "Alpha-amylase 1", "aln": "-----------------------MKFFLLLSLIGFCWAQYDPHTQYGRTAIVHLFEWRWVDIAKECERYLAPNGFAGVQVSPPNENIVVHSPSRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAQAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCRTASGGIENYQDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVMRKWDGEKMSYLKNWGEGWGLMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYYWPRNFQNGKDVNDWVGPP-NNNGKTKEVSINPDSTCGNDWICEHRWRQIRNMVAFRNVVNGQPFANWWDNDSNQVAFGRGNKGFIVFNNDDWALSETLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGNDGKAHFSISNSAEDPFIAIHAESKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2M0-1", "uniprot_id": "A0ABK0M2M0_RAT", "id": "A0ABK0M2M0-1", "name": "Alpha-amylase", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWDFNDNKCN---GEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKFGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWTRNFQNGKDVNDWIGPP-NNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LP04-1", "uniprot_id": "A0ABK0LP04_RAT", "id": "A0ABK0LP04-1", "name": "Alpha-amylase", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFAGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWDFNDNKCN---GEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKFGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWTRNFQNGKDVNDWIGPP-NNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00689-1", "uniprot_id": "AMYP_RAT", "id": "P00689-1", "name": "Pancreatic alpha-amylase", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCN---GEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPP-NNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00688-1", "uniprot_id": "AM2A5_MOUSE", "id": "P00688-1", "name": "Pancreatic alpha-amylase 2a5", "aln": "-----------------------MKFVLLLSLIGFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNENVVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCGAGNPAGTSSTCGSYLNPNNREFPAVPYSAWDFNDNKCN---GEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKW-FSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGLVPSDRALVFVDNHDNQRGHGAGGSSILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWNRNFQNGKDQNDWIGPP-NNNGVTKEVTINADTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWALSATLQTGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFIAIHADSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DTE7-1", "uniprot_id": "AMY1B_HUMAN", "id": "P0DTE7-1", "name": "Alpha-amylase 1B", "aln": "-----------------------MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNW-FPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPP-NDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DTE8-1", "uniprot_id": "AMY1C_HUMAN", "id": "P0DTE8-1", "name": "Alpha-amylase 1C", "aln": "-----------------------MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNW-FPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPP-NDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DUB6-1", "uniprot_id": "AMY1A_HUMAN", "id": "P0DUB6-1", "name": "Alpha-amylase 1A", "aln": "-----------------------MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNW-FPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPP-NDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04746-1", "uniprot_id": "AMYP_HUMAN", "id": "P04746-1", "name": "Pancreatic alpha-amylase", "aln": "-----------------------MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNW-FPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPP-NNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19961-1", "uniprot_id": "AMY2B_HUMAN", "id": "P19961-1", "name": "Alpha-amylase 2B", "aln": "-----------------------MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMSGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLVGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNW-FPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPP-NNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TC54-1", "uniprot_id": "A0AB32TC54_DANRE", "id": "A0AB32TC54-1", "name": "Alpha-amylase", "aln": "------------------MRKGTMKLLVVAALVGLCLSQHNTNFKHNRTSIVHLFEWRWADIAKECERYLAPNGYGGVQISPPSESIVLTKPWHPWWQRYQPISYNLCSRSGTEEELKDMIARCNNVGVNIYADAVINHMCGASGGEGTHSSCGTYFNAKNEDFPSVPYSSWDFNDNKCKTANEDIENYSDIFQVRDCRLVSLLDLALEKDYVRGKVAEYMNKLIDIGVAGFRVDACKHMWPGDLSNVYSRLKTLNTTW-FSPGTKPFIYQEVIDLGGEPIKASEYVSLGRVTEFKYSAKLGTVIRKWEKEKLCYLKNWGEGWGFMPSHKALVFVDNHDNQRGHGAGGASVLTFWDSRLYKIATGLMLAHPYGVTAVMSSYRWDRHFVNGKDQNDWMGPPSNADGSTKSVPINPDSTCGDNWICEHRWRQIRNMVIFRNVVNGQPLSNWWDNNNNQIAFSRGSKGFIVINNDDWDLNVTLKTGLPSGTYCDIISGDKSGNSCTGKQVTVDSDGQATFSICHTEEDPFMAIHADSKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08144-1", "uniprot_id": "AMYA_DROME", "id": "P08144-1", "name": "Alpha-amylase A", "aln": "--------------------MFLAKSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDS--RPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADG---GTYGTGGSTASPSSKSYPGVPYSSLDFNP------TCAISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKVFR--GKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQ---------GPPTTDGHNIASPIFNSDNSCSGGWVCEHRWRQIYNMVAFRNTVGLDEIQNWWDNGSNQISFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRASIYIGSSEDDGVLAIHVNAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :... :*...: .*:.:******:* *** ***.:*.*:*:.***:** .*. . :***:****:**:: :***.*::: .*: *** ***. *.*.*:***.. . * .: *: .. ...:..****. ** *.**.* :**:*.* .* ** :.**: *:.:::::***:******:**.*****.*: : .:*:.**: *. *::.:* *****:***.:. .:* . * :***:.. .:*.*:* ::: **.*** .**: .:.::*****************:.:**: .: **:* .:*****:* . ****: *** . . . :*.*.:*...*:******** *** ***.*. : : **:**..**::*.**.:**:.:***:: :. :*:****:*****:***.* ...*** : *..**.* : * : :* .:***.::*:", "identical_positions": 214, "similar_positions": 177, "identity": "39.93%" }, { "cls_id": "homologset.agr.FB:FBgn0000083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14668-1", "uniprot_id": "ANXA5_RAT", "id": "P14668-1", "name": "Annexin A5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALRG-TVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48036-1", "uniprot_id": "ANXA5_MOUSE", "id": "P48036-1", "name": "Annexin A5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATRG-TVTDFPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08758-1", "uniprot_id": "ANXA5_HUMAN", "id": "P08758-1", "name": "Annexin A5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQVLRG-TVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCG-EDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55260-1", "uniprot_id": "ANXA4_RAT", "id": "P55260-1", "name": "Annexin A4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METKGGTVKAASGFNATEDAQVLRKAMKGLGTDEDAIIGVLACRNTAQRQEIRTAYKSTIGRDLLEDLKSELSSNFEQVILGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRNPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLTAGGRDEGNYLDDALVRQDAQDLYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKPAYFAERLYKSMKGLGTDDSTLIRVMVSRAEIDMLDIPANFKRVYGKSLYSFIKGDTSGDYRKVLLILCGGDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97429-1", "uniprot_id": "ANXA4_MOUSE", "id": "P97429-1", "name": "Annexin A4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAKGGTVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09525-1", "uniprot_id": "ANXA4_HUMAN", "id": "P09525-1", "name": "Annexin A4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7FLB7-1", "uniprot_id": "F7FLB7_RAT", "id": "F7FLB7-1", "name": "Annexin", "aln": "MSGARLCSTGKAQGFLQEVTTKSAALTCGRGHTHPAPPERPRPAPLLWLRPGESKAAAPGEFSALRAPPPTVRRHSRVEIRKARLGGSCYPSSVSRSLVPALPMSYPGYPPPAGGYPPGAPGGAPWGGASYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNMYPGAPGGGYPPVPPGGFGQPPPAQQPVPPYGMYPPPGGNPPPGMPSYPAYPGAPVPGQPMPPPGQQPPGAYPGQPPMTYPGQSPMPPPGQQPVPS--YPGYSG--SSTITPAVPPAQFGNRG-TITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEILASRSNEHIRELNRAYKTEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKICGGND-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97384-1", "uniprot_id": "ANX11_MOUSE", "id": "P97384-1", "name": "Annexin A11", "aln": "-------------------------------------------------------------------------------------------------------MSYPGYPPPAGGYPPAAPGGGPWGGAGYPPPSMPPIGLDNVANYAGQFNQDYLSGMAANMSGTFGGANVPNLYPGAPGGGYPPVPPGGFGQPPPAQQPVPPYGMYPPPGGNPPPGMPSYPAYPGAPVPGQPMPPTGQQPPGAYPGQPPMTYPGQSPMPPPGQQPVPS--YPGYSG--SSTITPAVPPAQFGNRG-TITAASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEIFASRSNEHIRELSRAYKTEFQKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKICGGND-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PC84-1", "uniprot_id": "A0A8M1PC84_DANRE", "id": "A0A8M1PC84-1", "name": "Annexin", "aln": "-------------------------------------------------------------------------------------------------------MSYPGYPPAGGSYPPAS-GPYQQPAAGYPP--QPGAYPPQAGYYPPQP------GAFPPQPGAFPPQ--PGAFP--PGAGYPPQ-AGGYPAAPGGGFP-PQAGGYPAAQPGAYPNMPAAGGWGGHPGFG---APAGGMPQG-YPGVP---APGQQPMPAYPGAPVPNPGMPGYGGGAPTGPTPPAPAINRGFRG-TIKDFPGADPLRDVEVLRKAMKGFGTDENAIIELLGSRSNKQRVPLLAAYKTTYGKDLVRDLKSELTGHFEELVLAMLKSPAQFDASECKEAISGAGTDEACLIEILSSRSNAEIQEINRIYKAEYGKSLEDAISNDTSGHFRRLLVSLCQGNRDERETVDISLAKQDAQKLYSAGENKVGTDESQFNAILCARSKPHLRQVFQEYQQMCGRDIEKSICREMSGDLESGMVAVVKCIKNTPAYFAERLHKAMQGAGTKDRTLIRIMVSRSELDMLDIRQEYLRLFGKSLYTHISGDTSGDYKKLLLKLCGGSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22464-1", "uniprot_id": "ANXB9_DROME", "id": "P22464-1", "name": "Annexin B9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAEYYPFKCTP-TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKEDAETDIGYVLVTLTAW---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07076-1", "uniprot_id": "ANXA7_MOUSE", "id": "Q07076-1", "name": "Annexin A7", "aln": "-------------------------------------------------------------------------------------------------------MSYPGYPPTG-----------YPPFPGYPPAGQESSFP------------------------TAGQYPYPSGFPPMGGGAYPPAPSGGYPGAGG----YPAPGGYPAPGG--YPGALSPGGPPAYPGGQGFGAPPGGAGFSGYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGQAPYPSQPAS-MTQGTQG-TILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQSVNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ---", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : *. *******:****.:*: : *. ** : :*: *:**: *:**** .::*. ::.:: . : . . : *:.* **:* : **:.: . : : : *: .: **. : .*** :.*: : : ..** :: *.* *. *** : **** * :: :*. :* : * : :: .:: * ** .*. : ::::. . :::* * :* * **.* **:*::*:*:*:*: :* : . : .:* * *:. * *: : . ", "identical_positions": 81, "similar_positions": 102, "identity": "13.24%" }, { "cls_id": "homologset.agr.FB:FBgn0000084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXN8-1", "uniprot_id": "D3ZXN8_RAT", "id": "D3ZXN8-1", "name": "", "aln": "--------------------MFCGEYVQG----TIFPAPNFNPMMDAQVIDGALQGFECNKDLLIDILTQRSNAQRQMIAGTYQSMYGRDLIADLKEQLSSHFKEVMVGLMYPPPSYDAHELWHAMKGAGTDENCLIEILASRTNGEIFQMREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGNRE--EGYTDPAMAAQDAMVLWEACQQKTGEHKTMLQMILCNKSYPQLWLIFQEFQTISGQDLVDTISDCYDGYFQELLIAIVRCVQDKPSYFAYKLYRAIHDFGFHNKTVIRILIARSEIDLMTIRKRYKERFGKSLFH-DIKSFASGHYKKALLAICAGDVEDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ10-1", "uniprot_id": "ANX10_MOUSE", "id": "Q9QZ10-1", "name": "Annexin A10", "aln": "--------------------MFCGEYVQG----TIFPAPNFNPMMDAQMLGGALQGFDCNKDMLIDILTQRSNAQRQMIAGTYQSMYGRDLISVLKEQLSSHFKEVMVGLMYPPPSYDAHELWHAMKGPGTDENCLIEILASRTNGEIFQMREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQANRE--EGYSDPAMAAQDAMVLWEACQQKTGEHKTMMQMILCNKSYPQLWLVFQEFQNISGQDLVDAINDCYDGYFQELLVAIVRCIQDKPSYFAYKLYRAIHDFGFHNKTVIRILIARSEIDLMTIRKRYKERFGKSLFH-DIKNFASGHYEKALLAICAGDVEDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJ72-1", "uniprot_id": "ANX10_HUMAN", "id": "Q9UJ72-1", "name": "Annexin A10", "aln": "--------------------MFCGDYVQG----TIFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTRE--EGYTDPAMAAQDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKPAYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFH-DIRNFASGHYKKALLAICAGDAEDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14668-1", "uniprot_id": "ANXA5_RAT", "id": "P14668-1", "name": "Annexin A5", "aln": "--------------------MALRG--------TVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRD-PDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYS-MIKGDTSGDYKKALLLLCGGEDD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48036-1", "uniprot_id": "ANXA5_MOUSE", "id": "P48036-1", "name": "Annexin A5", "aln": "--------------------MATRG--------TVTDFPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRD-PDTAIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYS-MIKGDTSGDYKKALLLLCGGEDD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4FZU6-1", "uniprot_id": "ANXA8_RAT", "id": "Q4FZU6-1", "name": "Annexin A8", "aln": "--------------------MAWWKAWVEQEGVSVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGDTSGYLERILVCLLQGCRDDVSGFVDPGLALQDAQDLHAAGEKILGTDEMKFITILCTRSATHLMRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTLDGTLIRNIVSRSEIDLNLIKSQFQKMYGKTLSS-MIMGDTSGYYKTALLNLVGTDL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35640-1", "uniprot_id": "ANXA8_MOUSE", "id": "O35640-1", "name": "Annexin A8", "aln": "--------------------MAWWKAWVEQEGVSVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYSYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGDTSGYLERILVCLLQGSRDDVSGFVDPGLVLQDAQALHEAGEKIMGTDEMKFITILCTRSATHLMRVFEEYEKIANKCIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKGQFKKMYGKTLSS-MIMADTSGYYKTALLNLVGTDL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13928-1", "uniprot_id": "ANXA8_HUMAN", "id": "P13928-1", "name": "Annexin A8", "aln": "--------------------MAWWKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSS-MIMEDTSGDYKNALLSLVGSDP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VT79-1", "uniprot_id": "AXA81_HUMAN", "id": "Q5VT79-1", "name": "Annexin A8-like protein 1", "aln": "--------------------MAWWKAWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSS-MIMEDTSGDYKNALLSLVGSDP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22465-1", "uniprot_id": "ANX10_DROME", "id": "P22465-1", "name": "Annexin B10", "aln": "--------------------MEYKPVP------TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDELGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPLAEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHASFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDDATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLGSA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZSA0-1", "uniprot_id": "D3ZSA0_RAT", "id": "D3ZSA0-1", "name": "Annexin", "aln": "MSVSCGPLGTSLTQEILRSLGLADKTAAWGTLGTLRTFLSFSVDKDVQRLLKAIAGQGVDCSTIVDVLTNRSREQRQLISRAFQERTKQDLLKSLQAALSGNLEKIVVALLQPAAQFDAQELRTALKTSGSAEDVALEILATRAAPRLQECLAVYKHDFQVEAEEDLRTETNGILQDLLLALSKGARESYSGVIDYNLEEQDVQALQQTGEPS----AGQWVLLFTQRSPEHLIRVFDLYRRCTGQELEDAIRNCFHGDAQRALISLASMMRNTALYFANKLHQALQETEPNFRVLMRVLISRSESDLLSIRAEFKKKFGKSLYS-SLQDAVGGDCRSALLALCRAEDI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHQ0-1", "uniprot_id": "ANXA9_MOUSE", "id": "Q9JHQ0-1", "name": "Annexin A9", "aln": "MSASCGPLGTSLTQEILSSLGLADKTAAWGTLGTLRTFLSFSVDKDVQRLLKAIAGQGVDYDTIVDVLTNRSREQRQLISRAFQERTKQDLLKSLQAALSGNLEKIVVALLQPAAQFDAQELRTALKTSGSAEDVALEILATRAAPGLQACLAVYKHDFQVEAEEDIRTETNGILQDLLLALSKGDRESYSGIIDYNLEEQDVRALQQAGESST---AGQWVLLLTQRSPEHLIRVFDQYRRCTGQELEDAIRNCFHGDAQLALISLASMLRNTALYFANKLHQALQETEPNFQVLTRVLISRSESDLLSIRAEFKKKFGKSLYS-SLQDVVRGDCRSALLALCRAEDI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76027-1", "uniprot_id": "ANXA9_HUMAN", "id": "O76027-1", "name": "Annexin A9", "aln": "MSVTGGKMAPSLTQEILSHLGLASKTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQRAEGPSR---EETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYS-SLQDAVKGDCQSALLALCRAEDM--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *. *.: : *: * : . ::::*. *.. ** * :: :** :: * .::: :: .:: *. : . :* *: .: **:.::: : .* : ::: :*.* . * : . *: . * :. * : :: . :* :*: : :. : ::: . . :: :. :. ::* *: *:: .: * :::*.* ** *: .:.. : :* : . * . ** : ", "identical_positions": 39, "similar_positions": 101, "identity": "11.11%" }, { "cls_id": "homologset.agr.FB:FBgn0000097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41212-1", "uniprot_id": "ETV6_HUMAN", "id": "P41212-1", "name": "Transcription factor ETV6", "aln": "MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVP-VPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSP--------FFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQ-RPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPR--HSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGR-----------------------------------------------------IADCRLLWDYVYQLLSD--SRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQE--------------------------LDEQIYQEDEC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97360-1", "uniprot_id": "ETV6_MOUSE", "id": "P97360-1", "name": "Transcription factor ETV6", "aln": "MSETPAQSSIKQERISYTPPESPVASHRSSTPLHVHTVPRALRMEEDSIHLPTHLRLQPIYWSRDDVAQWLKWAENEFSLRPIESNKFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKSRMLFSP--------FFPPGDSIHTKPEVLLHQNHDEDNCVQRTPRTPAESVHHNPPTIELLHRPRSPITTNHRPSPDPEQQRPQRSPLDNMSRRLSPVEKAQGPRLQQENNHQETYPLSVSPVENNHC--------LPSSPWQESTRVIQLMPSPIMHPLILNPRHSHSVDFKQSRHSEDGMNREGKPINLSHREDLAYLNHIMVSMSPPEEHAMPIGR-----------------------------------------------------IADCRLLWDYVYQLLSD--SRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQV--------------------------LDEQTYQEDEPTIASPVGWPRGNLPTGTAGGVMEAGELGVAVKEETRE--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y603-1", "uniprot_id": "ETV7_HUMAN", "id": "Q9Y603-1", "name": "Transcription factor ETV7", "aln": "MQE--GELAISP--ISPVAAMPPLGTHVQAR----CEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWLRWAEQEYSLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKTQRR-ALVCGP--------FFGG------------------------------------------IFRLKTP--TQHSPVPPEEVTGPSQ-----MDTRRGHLLQPPDPGLTSNFGHLDDPGLAR------------------WTPGKEES------------------------------------------LNLCHCAELGCRTQGVCSF-PAMPQAPIDGR-----------------------------------------------------IADCRLLWDYVYQLLLD--TRYEPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHLEPLESQE--------------------------QDRIEFKDKRPEISP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01842-1", "uniprot_id": "POK_DROME", "id": "Q01842-1", "name": "Ets DNA-binding protein pokkuri", "aln": "----MSKMKMLPVQLSLNSLNPGIWSDVLWR----CPPAPSSQLAELKTQLPPSLPSDPRLWSREDVLVFLRFCVREFDLPKLDFDLFQMNGKALCLLTRADFGHRCPGAGDVLHNVLQMLIIESHMMQWHLPNSPVTPTSRYPLSPHSHPPTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSVTLSPPPSVDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQQSQQQQQSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPNSPALNTPSAVGGPDKFQFHPLKLENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPLIRNADGLTTIKLIRYNEHQVAASPAGQSPKHDDQQAGASNASSSPRPMDQASEQAQPVPMESDCNGGESEDSFRHMQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : :* . . : : :** * :* ***:** :*::. .*:.* . *:***:** :**: ** :*.* :****:::** : : : * : : : * . . . . :* : :* : : :. . :* :: *****:: *** * :*. * *: ::: :*::*** ***:*** :**: .*.*:*******:**::**::* *:: ::*::.* :: . : * .: :. ::.. ", "identical_positions": 78, "similar_positions": 91, "identity": "10.54%" }, { "cls_id": "homologset.agr.FB:FBgn0000100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHW5-1", "uniprot_id": "RLA0L_HUMAN", "id": "Q8NHW5-1", "name": "Putative ribosomal protein uL10-like", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKVVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIWGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLVIQQVFDNGSIYNPEVLDKTEETLHSRFLEGVRNVASVCLQTGYPTVASVPHSIINGYKRVLALSVETDYTFPLAENVKAFLADPSAFVAAAPVAADTTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05388-1", "uniprot_id": "RLA0_HUMAN", "id": "P05388-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFVAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19945-1", "uniprot_id": "RLA0_RAT", "id": "P19945-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLIIQQVFDNGSIYSPEVLDITEQALHTRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14869-1", "uniprot_id": "RLA0_MOUSE", "id": "P14869-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLIIQQVFDNGSIYNPEVLDITEQALHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETEYTFPLTEKVKAFLADPSAFAAAAPAAAATTAAPAAAAAPAKAEAKEESEESDEDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJT4-1", "uniprot_id": "D3ZJT4_RAT", "id": "D3ZJT4-1", "name": "60S acidic ribosomal protein P0", "aln": "MPREDRVTCKSNYFLKIIQLLDDYPKCFIMGADNVSSKQMQQIRMSLQGKAVVLMIKNNAMMRKAIREHLEKNRALEKLPPHTRGNVGFMFTKEDLTEIRDMLLTNKVPAATQAGALAPCEVTAHAQNTGLGPEKTSFFQVLGINTKISRGIIEILSDVQLIKTGNKVGAGEATLL------NISPSVSGLIIRQVFDNGSIYNPEVLDITEQILRSHFLEGVRNVAAVCLQIGEPTVTSVPHSIINGSKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKAKAKEESEESDEDVRFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9PV90-1", "uniprot_id": "RLA0_DANRE", "id": "Q9PV90-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDFPKCFIVGADNVGSKQMQTIRLSLRGKAVVLMGKN-TMMRKAIRGHLENNPALERLLPHIRGNVGFVFTKEDLTEVRDLLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKPGDKVGASEATLLNMLNMLNISPFSYGLIIQQVYDNGSVYSPEVLDITEDALHKRFLKGVRNIASVCLQIGYPTLASIPHTIINGYKRVLAVTVETDYTFPLAEKVKAYLADPTAFAVAAPVAAATEQKSAAPAAKEEAP-KEDSEESDEDMGFGLFD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19889-1", "uniprot_id": "RLA0_DROME", "id": "P19889-1", "name": "Large ribosomal subunit protein uL10", "aln": "MVRENKAAWKAQYFIKVVELFDEFPKCFIVGADNVGSKQMQNIRTSLRGLAVVLMGKN-TMMRKAIRGHLENNPQLEKLLPHIKGNVGFVFTKGDLAEVRDKLLESKVRAPARPGAIAPLHVIIPAQNTGLGPEKTSFFQALSIPTKISKGTIEIINDVPILKPGDKVGASEATLLNML---NISPFSYGLIVNQVYDSGSIFSPEILDIKPEDLRAKFQQGVANLAAVCLSVGYPTIASAPHSIANGFKNLLAIAATTEVEFKEATTIKEYIKDPSKFAAAASASAAPAAGGATEKKEEAKKPESESEEEDDDMGFGLFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05317-1", "uniprot_id": "RLA0_YEAST", "id": "P05317-1", "name": "Large ribosomal subunit protein uL10", "aln": "--MGGIREKKAEYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKELRGRAVVLMGKN-TMVRRAIRGFLSDLPDFEKLLPFVKGNVGFVFTNEPLTEIKNVIVSNRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGNKVGQSEASLLNLL---NISPFTFGLTVVQVYDNGQVFPSSILDITDEELVSHFVSAVSTIASISLAIGYPTLPSVGHTLINNYKDLLAVAIAASYHYPEIEDLVDRIENPEKYAAAAPAATSAASGDAAPAEEAAAE---EEEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::** *: : :::: . *::*.***.*:**: :* .*:* .**** ** :*:*:*** .*.. :*:* *. *****:**: *:*::: :: .:* *.::.**:** .: * ***: * ******.*.: ***::* ***:.** ::..*:*** .**:** **** ** : **:*.*.:: ..:** . : * :* ..* .:*::.* * **:.* *:: *. * :**:: :. : : : :* :..**..:: . *: :.**.*:*: *****", "identical_positions": 113, "similar_positions": 108, "identity": "35.2%" }, { "cls_id": "homologset.agr.FB:FBgn0000108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15943-1", "uniprot_id": "APLP2_RAT", "id": "P15943-1", "name": "Amyloid beta precursor like protein 2", "aln": "MAATGTAAAAATGK-----LLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQT-GKWEPDPTGTKS---CLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRR--DKK-QCRSH--IVIPFKCLVGEFVSDVLLVPENCQFFHQERMEVCEKHQRWHTVVKEACLTEGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKVVDSDSTMSKEEEEEEE--EDEEEDYALD-KSEFPTEADLEDFTEAAADEDEDEEEEEEEEGEEVVEDRDYYYDSFKGDDYNEENPTEPSSDGTISDKEIAHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPLPTN--------------------------DVDVYFETSADDNEHARFQKAKEQLEIRHRSRMDRVKKEWEEAELQAKNLPKAE-------RQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDP----EKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQ-EQRAD-----------------------------------------------------------------MDQFTSSISENPVDVRVSSEESEEIPPFHPFHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSK-----------------NKMDENMVIDETLDVKEMIFNAER--VGGLEEEPDSVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ-YGTISHGIVEVHPMLTP------EERHLNKMQNHGYENPTYKYLEQMQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06335-1", "uniprot_id": "APLP2_MOUSE", "id": "Q06335-1", "name": "Amyloid beta precursor like protein 2", "aln": "MAATGTAAAAATGK-----LLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQT-GKWEPDPTGTKS---CLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRR--DKR-QCKSH--IVIPFKCLVGEFVSDVLLVPDNCQFFHQERMEVCEKHQRWHTLVKEACLTEGLTLYSYGMLLPCGVDQFHGTEYVCCPQTKTVDSDSTMSKEEEEEEEDEEDEEEDYDLD-KSEFPTEADLEDFTEAAADE----EEEDEEEGEEVVEDRDYYYDPFKGDDYNEENPTEPSSEGTISDKEIVHDVK--------------------------------------------------------VPPTPLPTN--------------------------DVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKTE-------RQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDP----EKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQ-EQRAD-----------------------------------------------------------------MDQFTSSISENPVDVRVSSEESEEIPPFHPLHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSK-----------------NKMDENMVIDETLDVKEMIFNAER--VGGLEEEPESVGPLREDFSLSSNALIGLLVIAVAIATVIVISLVMLRKRQ-YGTISHGIVEVDPMLTP------EERHLNKMQNHGYENPTYKYLEQMQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06481-1", "uniprot_id": "APLP2_HUMAN", "id": "Q06481-1", "name": "Amyloid beta precursor like protein 2", "aln": "MAATGTAAAAATGR-----LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQT-GKWEPDPTGTKS---CFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRR--DKK-QCKSR--FVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVY-KSEFPTEADLEDFTEAAVDE----DDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTN--------------------------DVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAE-------RQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDP----EKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQ-EQRAD-----------------------------------------------------------------MDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVINSK-----------------NKVDENMVIDETLDVKEMIFNAER--VGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ-YGTISHGIVEVDPMLTP------EERHLNKMQNHGYENPTYKYLEQMQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08592-1", "uniprot_id": "A4_RAT", "id": "P08592-1", "name": "Amyloid-beta precursor protein", "aln": "MLPS---------------LALLLLAAWTVRALEVP-----TDGNAG---LLAEPQIAMFCGKLNMHMNVQN-GKWESDPSGTKT---CIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR--GRK-QCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSIDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEE--AEDDEDVEDGDEVEEEAEEPYEEAT------ERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVSSQSLLKTTSEPLPQDPVKLPTTA------ASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKAD-------KKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP----KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS-----------------------------------------------------------------DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGL--------------TTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQ-YTSIHHGVVEVDAAVTP------EERHLSKMQQNGYENPTYKFFEQMQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12023-1", "uniprot_id": "A4_MOUSE", "id": "P12023-1", "name": "Amyloid-beta precursor protein", "aln": "MLPS---------------LALLLLAAWTVRALEVP-----TDGNAG---LLAEPQIAMFCGKLNMHMNVQN-GKWESDPSGTKT---CIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR--GRK-QCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEE--ADDDEDVEDGDEVEEEAEEPYEEAT------ERTTSTATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQDPDKLPTTA------ASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKAD-------KKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP----KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS-----------------------------------------------------------------DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGL--------------TTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQ-YTSIHHGVVEVDAAVTP------EERHLSKMQQNGYENPTYKFFEQMQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05067-1", "uniprot_id": "A4_HUMAN", "id": "P05067-1", "name": "Amyloid-beta precursor protein", "aln": "MLPG---------------LALLLLAAWTARALEVP-----TDGNAG---LLAEPQIAMFCGRLNMHMNVQN-GKWDSDPSGTKT---CIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKR--GRK-QCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEE--ADDDEDDEDGDEVEEEAEEPYEEAT------ERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTA------ASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKAD-------KKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP----KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS-----------------------------------------------------------------DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGL--------------TTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQ-YTSIHHGVVEVDAAVTP------EERHLSKMQQNGYENPTYKFFEQMQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LRS5-1", "uniprot_id": "F1LRS5_RAT", "id": "F1LRS5-1", "name": "Amyloid beta precursor like protein 1", "aln": "MGPSSPTTRGQGRRRGPPPLPLLLPLSLLLLRAQLAVG-NLAGGSPSAAEAPGSAQVAGLCGRLTLHRDLRT-GRWEPDPQRSRR---CLLDPQRVLEYCRQMYPELHIARVEQAAQAIPMERWCGG--TRSGRCAHPHHEVVPFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPATPNPSGMAVGDPSTRSWPLGGRAEGGEDEEEVESFPQPVDDYFVEPPQAE------EEEEEEEERAP------------------PPSSHTPVMVSR----------------------------------------------------------------VTPTPRPTD--------------------------GVDVYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADSQSKNLPKAD-------RQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQAERVLMALRRYLRAEQKEQRHTLRHYQHVAAVDP----EKAQQMRFQVQTHLQVVQERMNQSLGLLDQNPHLAQELRPQIQELLHAEHLGP-----------------------------------------------------------------SELEASVPGSSSEDKGS-------------LQPPESKDDAPVTLPKGSTDQESSSSGREKLTPLEQYEQKVNASAP--------------------RGFPFHSS------------------DIQRDELAPAGTGVS--REALSGLLIMGAGGGSLIVLSLLLLRKKKPYGTISHGV--VDPMLTL------EEQQLRELQRHGYENPTYRFLEERP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03157-1", "uniprot_id": "APLP1_MOUSE", "id": "Q03157-1", "name": "Amyloid beta precursor like protein 1", "aln": "MGPTSPAARGQGRRWRPPPLPLLLPLSLLLLRAQLAVG-NLAVGSPSAAEAPGSAQVAGLCGRLTLHRDLRT-GRWEPDPQRSRR---CLLDPQRVLEYCRQMYPELHIARVEQAAQAIPMERWCGG--TRSGRCAHPHHEVVPFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPATPNPSGMAAGDPSTRSWPLGGRAEGGEDEEEVESFPQPVDDYFVEPPQAE------EEEEEEEERAP------------------PPSSHTPVMVSR----------------------------------------------------------------VTPTPRPTD--------------------------GVDVYFGMPGEIGEHEGFLRAKMDLEERRMRQINEVMREWAMADSQSKNLPKAD-------RQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQAERVLMALRRYLRAEQKEQRHTLRHYQHVAAVDP----EKAQQMRFQVQTHLQVIEERMNQSLGLLDQNPHLAQELRPQIQELLLAEHLGP-----------------------------------------------------------------SELDASVPGSSSEDKGS-------------LQPPESKDDPPVTLPKGSTDQESSSSGREKLTPLEQYEQKVNASAP--------------------RGFPFHSS------------------DIQRDELAPSGTGVS--REALSGLLIMGAGGGSLIVLSLLLLRKKKPYGTISHGVVEVDPMLTL------EEQQLRELQRHGYENPTYRFLEERP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51693-1", "uniprot_id": "APLP1_HUMAN", "id": "P51693-1", "name": "Amyloid beta precursor like protein 1", "aln": "MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIG-SLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRT-GRWEPDPQRSRR---CLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGG--SRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAE------EE----EETVP------------------PPSSHTLAVVGK----------------------------------------------------------------VTPTPRPTD--------------------------GVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKAD-------RQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDP----EKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGP-----------------------------------------------------------------SELEAPAPGGSSEDKGG-------------LQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVP--------------------RGFPFHSS------------------EIQRDELAPAGTGVS--REAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTL------EEQQLRELQRHGYENPTYRFLEERP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14599-1", "uniprot_id": "A4_DROME", "id": "P14599-1", "name": "Amyloid-beta-like protein", "aln": "-------------------MCAALRRNLLLRSLWVVLAIGTAQVQAASPRWEPQIAVLCEAGQIYQPQYLSEEGRWVTDLSKKTTGPTCLRDKMDLLDYCKKAYPNRDITNIVESSHYQKIGGWCRQGALNAAKCKGSHRWIKPFRCLG-PFQSDALLVPEGCLFDHIHNASRCWPFVRWNQTGAAACQERGMQMRSFAMLLPCGISVFSGVEFVCCPKHFKTDEIHVKKTDLPVMPAAQINSANDELVMNDEDDSNDSNYSKDANEDDLDDEDDLMGDDEEDDMVADEAATAGGSPNTGS---SGDSNSGSLDDINAEYDSGEEGDNYEEDGAGSESEAEVEASWDQSGGAKVVSLKSDSSSPSSAPVAPAPEKAPVKSESVTSTPQLSASAAAFVAANSGNSGTGAGAPPSTAQPTSDPYFTHFDPHYEHQSYKVSQKRLEESHREKVTRVMKDWSDLEEKYQDMRLADPKAAQSFKQRMTARFQTSVQALEEEGNAEKHQLAAMHQQRVLAHINQRKREAMTCYTQALTEQPPNAHHVEKCLQKLLRALHKDRAHALAHYRHLLNSGGPGGLEAAASERPRTLERLIDIDRAVNQSMTMLKRYPELSAKIAQLMNDYILALRSKDDIPGSSLGMSEEAEAGILDKYRVEIERKVAEKERLRLAEKQRKEQRAAEREKLREEKLRLEAKKVDDMLKSQVAEQQSQPTQSSTQSQAQQQQQEKSLPGKELGPDAALVTAANPNLETTKSEKDLSDTEYGEATVSSTKVQTVLPTVDDDAVQRAVEDVAAAVAHQEAEPQVQHFMTHDLGHRESSFSLRREFAQHAHAAKEGRNVYFTLSFAGIALMAAVFVGVAVAKWRTSRSPHAQGFIEVDQNVTTHHPIVREEKIVPNMQINGYENPTYKYFEVKE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ... . : .*:: : *:* .* . *: :*:**:: **: .*:.: :: : : ** . * : *::** * *:.****: * * * .. . * : : :* .. : . .****** . * *.*:**** . : . . . . . . .: : : : .. : . : : * *: ** : :: ** : :: .* ::* : : ::: :: :: : :** :::**:: *:::*. * ** * :*:::* *: : ** **...:: *:: :** :*:: *:: *:.*: . : * . : :. :* : . ***: :* . * :: :: ::: : : : . . : : : . .: .. . * . . : :.: : : : : . :*. *. :* **: : ::* :*******:::* ", "identical_positions": 96, "similar_positions": 175, "identity": "10.54%" }, { "cls_id": "homologset.agr.FB:FBgn0000109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36972-1", "uniprot_id": "APT_RAT", "id": "P36972-1", "name": "Adenine phosphoribosyltransferase", "aln": "MS-----ESELQLVARRIRSFPDFPIPGVLFRDISPLLKDPDSFRASIRLLAGHLKSTHGG-KIDYIAGLDSRGFLFGPSLAQELGVGCVLIRKRGKLPGPTVSASYSLEYGKAELEIQKDALEPGQKVVIVDDLLATGGTMCAACELLSQLRAEVVECVSLVELTSLKGREKLGPVPFFSLLQYE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08030-1", "uniprot_id": "APT_MOUSE", "id": "P08030-1", "name": "Adenine phosphoribosyltransferase", "aln": "MS-----EPELKLVARRIRSFPDFPIPGVLFRDISPLLKDPDSFRASIRLLASHLKSTHSG-KIDYIAGLDSRGFLFGPSLAQELGVGCVLIRKQGKLPGPTVSASYSLEYGKAELEIQKDALEPGQRVVIVDDLLATGGTMFAACDLLHQLRAEVVECVSLVELTSLKGRERLGPIPFFSLLQYD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07741-1", "uniprot_id": "APT_HUMAN", "id": "P07741-1", "name": "Adenine phosphoribosyltransferase", "aln": "MA-----DSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGG-RIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12426-1", "uniprot_id": "APT_DROME", "id": "P12426-1", "name": "Adenine phosphoribosyltransferase", "aln": "MSPSISAEDKLDYVKSKIGEYPNFPKEGILFRDIFGALTDPKACVYLRDLLVDHIRESAP--EAEVIVGLDSRGFLFNLLIATELGLGCAPIRKKGKLAGEVVSVEYKLEYGIDTFELQKSAIKPGQKVVVVDDLLATGGSLVAATELIGKVGGVVVESLVVMELVGLEGRKRLDGK-VHSLIKY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36973-1", "uniprot_id": "APT2_YEAST", "id": "P36973-1", "name": "Adenine phosphoribosyltransferase 2", "aln": "MS---ISESYAKEIKTAFRQFTDFPIEGEQFEDFLPIIGNPTLFQKLVHTFKTHLEEKFGKEKIDFIAGIEARGLLFGPSLALALGVGFVPIRRVGKLPGECASITFTKLDHEEIFEMQVEAIPFDSNVVVVDDVLATGGTAYAAGDLIRQVGAHILEYDFVLVLDSLHGEEKLSAP-IFSILHS-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P49435-1", "uniprot_id": "APT1_YEAST", "id": "P49435-1", "name": "Adenine phosphoribosyltransferase 1", "aln": "MS---IAS-YAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAP-VFTLLNAQKEALKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . . : : .:.:** * *.*: : :* : *:. . : *.*:::**:**. :* **:* . :*: ***.* : :*:* .*: ...*::***::****: ** :*: :: . ::* :: * *.*..:* ..:::: ", "identical_positions": 42, "similar_positions": 62, "identity": "21.88%" }, { "cls_id": "homologset.agr.FB:FBgn0000114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQT3-1", "uniprot_id": "CELF1_RAT", "id": "Q4QQT3-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGTLDHPD------------------------------------------------------------------------------QPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKA-MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTANSGNLNTLS--SLHPMGGLNAMQLQNLAALAAAASAAQN--TPSGTNALTTSSSPLSVLTSSA----------------GSSPSSSSSNSVNPIASLGALQTLAG-ATAGLN-VGSLAG----MAALNGGLGSSGLSNGTGSTMEALTQ-AYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28659-1", "uniprot_id": "CELF1_MOUSE", "id": "P28659-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGTLDHPD------------------------------------------------------------------------------QPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKA-MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLS--SLHPMGGLNAMQLQNLAALAAAASAAQN--TPSGTNALTTSSSPLSVLTSS-----------------GSSPSSSSSNSVNPIASLGALQTLAG-ATAGLN-VGSLAG----MAALNGGLGSSGLSNGTGSTMEALTQ-AYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92879-1", "uniprot_id": "CELF1_HUMAN", "id": "Q92879-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGTLDHPD------------------------------------------------------------------------------QPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKA-MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLS--SLHPMGGLNAMQLQNLAALAAAASAAQN--TPSGTNALTTSSSPLSVLTSS-----------------GSSPSSSSSNSVNPIASLGALQTLAG-ATAGLN-VGSLAG----MAALNGGLGSSGLSNGTGSTMEALTQ-AYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9IBD0-1", "uniprot_id": "CELF1_DANRE", "id": "Q9IBD0-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGSLDHPD------------------------------------------------------------------------------QPDIDSIKMFVGQIPRTWSEDQLRELFEPYGAVYEINVLRDRSQNPPQSKGCCFVTYYTRKSALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFVGMISKKCNENDIRLMFSPYGQIEECRILRGPDGLSRGCAFVTFTARQMAQSAIKS-MHQSQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQLNAASMWGNLTGLNSLGPQYLALYLQLLQQSASSG--NALN--NLHPMSGLNAMQ--NLAALAAAASATQA--TPTGSSALTTSSSPLSVLTSSGTPSGQPAQSAWDAYKAGSSPTSSTSSSVNPMASLGALQSLAAGAGAGLN-MSSLAS----MAALNGGLGSGGLSNGSGSTMEALTQAAYSGIQQYAAAALPSLYSQSLLSQQNVSAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSSQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q792H5-1", "uniprot_id": "CELF2_RAT", "id": "Q792H5-1", "name": "CUGBP Elav-like family member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRCP---KSAVTMR-NEELLLSNGTANKMNGALDHSD------------------------------------------------------------------------------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKA-MHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTAT-WGNLTGLGGLTPQYLAL----LQQATSSSNLGAFS--GIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLSSTSSALGALTSPV---------------AASTPNSTAGAAMNSLTSLGTLQGLAG-ATVGLNNINALAG----MAALNGGLGATGLTNGTAGTMDALTQ-AYSGIQQYAAAALPTLYSQSLLQQQ--SAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H4-1", "uniprot_id": "CELF2_MOUSE", "id": "Q9Z0H4-1", "name": "CUGBP Elav-like family member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRCP---KSAVTMR-NEELLLSNGTANKMNGALDHSD------------------------------------------------------------------------------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKA-MHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTAT-WGNLTGLGGLTPQYLAL----LQQATSSSNLGAFS--GIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLSSTSSALGALTSPV---------------AASTPNSTAGAAMNSLTSLGTLQGLAG-ATVGLNNINALAG----MAALNGGLGATGLTNGTAGTMDALTQ-AYSGIQQYAAAALPTLYSQSLLQQQ--SAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95319-1", "uniprot_id": "CELF2_HUMAN", "id": "O95319-1", "name": "CUGBP Elav-like family member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRCP---KSAVTMR-NEELLLSNGTANKMNGALDHSD------------------------------------------------------------------------------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKA-MHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTAT-WGNLTGLGGLTPQYLAL----LQQATSSSNLGAFS--GIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLSTTSSALGALTSPV---------------AASTPNSTAGAAMNSLTSLGTLQGLAG-ATVGLNNINALAG----MAALNGGLGATGLTNGTAGTMDALTQ-AYSGIQQYAAAALPTLYSQSLLQQQ--SAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0B1-1", "uniprot_id": "CELF2_DANRE", "id": "Q6P0B1-1", "name": "CUGBP Elav-like family member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRYPSTANSAVSMRSTEELLLSNGTAGKMNGALEHSD------------------------------------------------------------------------------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLTGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPYGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKA-MHQSQTMEGCSSPMVVKFADTQKDKEQRRLQQQLAQQMQQLNSASAWGSLTGLTGLTPQYLAL----LQQATSSSNLGAFS--GIQQMAGMNALQLQNLATLAAAAAAAQSSASPSTASALTSSTGSLGALASP----------------AGSTANSSA--AMGSLGSLGTLQGLAG-ATVGLNNINALAGSVNSMAALNGGLGSTGLSNGSAGPMDALTQ-AYSGIQQYAAAALPTLYSQSLLQQQ--SAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP90-1", "uniprot_id": "Q8IP90_DROME", "id": "Q8IP90-1", "name": "", "aln": "MLSSLDALAGKIATATPGTGAVTADSKNTQSLHHHHRLDYDYSAVEIEPPAEQLANSPRSERERLQQAQQAYEQQAQAELEFGLAEVDAKLTQLKSSHSLQHHHSHHHQLQRHTALNQQQQQLHHHQPHHNHHHHHPYQRPRPTSPPQQQTSSYQQQLSQLAALQDHHDLLQTQQELFHKQLATMQEYQRERERERERERERERERERERDRSSFIDNSDYDSQTEFKICLRDSAFGMSDKSSSATNSLPNSPIHSNNNNPSLLNNNNNNSNGTSSNNSLNVGNNNSNPSLGGSNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDACFRLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATG--ISKGCCFVTFYTRHAALKAQDALHNVKTLNGMYHPIQMKPADSENRN---ERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNGQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLASNINIPLGQTATSVTTPILPNP----PQQPSPVLGADAITPASIQLLQQLQAVGLQHQLLQALTGLGAQQSSSATDTSAVAAAG-LLTPMTVQN----------------LAAIAAMTQPSLSNAAAAAAAATSPG--SAQLTNTAALLWS-----------DPNPMASAYMSTAAGLPQ------FGSASALSTSPLASVALSAAAAAAAGKQIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPK-DSKPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. ::.: :** * *******:*:: .*.:*:*:** ****:.**:***:: . ********:***::**:**:****:* * **:***********: * :****:**:.** .***:* :*. .* **** :**. :* *:*******::: * .*** : * : ****:**:*********:***::: * : : . . . :. * **.: .::. .:: : ::*: : * :. .:* :.: :..:::: * :: :: : : ::. : .: .. . *. :* .. ::.. .. .*.* *:* .: . * .***.* *****.*********** * *: . *:*****:**********.*********:*** *:*.**::*****:* ********:.* *****", "identical_positions": 202, "similar_positions": 136, "identity": "23.6%" }, { "cls_id": "homologset.agr.FB:FBgn0000115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61211-1", "uniprot_id": "ARL1_MOUSE", "id": "P61211-1", "name": "ADP-ribosylation factor-like protein 1", "aln": "MGGFFSSIFSSLFGT-REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61212-1", "uniprot_id": "ARL1_RAT", "id": "P61212-1", "name": "ADP-ribosylation factor-like protein 1", "aln": "MGGFFSSIFSSLFGT-REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40616-1", "uniprot_id": "ARL1_HUMAN", "id": "P40616-1", "name": "ADP-ribosylation factor-like protein 1", "aln": "MGGFFSSIFSSLFGT-REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25160-1", "uniprot_id": "ARL1_DROME", "id": "P25160-1", "name": "ADP-ribosylation factor-like protein 1", "aln": "MGGVLS-YFRGLLGS-REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQSRK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38116-1", "uniprot_id": "ARL1_YEAST", "id": "P38116-1", "name": "ADP-ribosylation factor-like protein 1", "aln": "MGNIFSSMFDKLWGSNKELRILILGLDGAGKTTILYRLQIGEVVTTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTASKELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKEEQL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..:* * * *: :*:********************:****** ******** ::*****::******************::* *:*:**** *:**:. :..** **.**** * *:*:***** .:: :*: : *.* **:*.:.*. :** ** *: :.::** :.::..: ", "identical_positions": 104, "similar_positions": 49, "identity": "56.83%" }, { "cls_id": "homologset.agr.FB:FBgn0000116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07335-1", "uniprot_id": "KCRB_RAT", "id": "P07335-1", "name": "Creatine kinase B-type", "aln": "MP--FSNSHNT--------------------------------QKLRFPAEDEFPDLSSHNN--HMAKVLTPELYAELRAKCTPSG-FTLDDAIQTGVDNPGHPYIMTVGAVAGDEESYDVFKDLFDPIIEDRHGGYQP-SDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLSGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGK-HEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQPIDDLMPAQK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04447-1", "uniprot_id": "KCRB_MOUSE", "id": "Q04447-1", "name": "Creatine kinase B-type", "aln": "MP--FSNSHNT--------------------------------QKLRFPAEDEFPDLSSHNN--HMAKVLTPELYAELRAKCTPSG-FTLDDAIQTGVDNPGHPYIMTVGAVAGDEESYDVFKDLFDPIIEERHGGYQP-SDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLSGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGK-HEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12277-1", "uniprot_id": "KCRB_HUMAN", "id": "P12277-1", "name": "Creatine kinase B-type", "aln": "MP--FSNSHNA--------------------------------LKLRFPAEDEFPDLSAHNN--HMAKVLTPELYAELRAKSTPSG-FTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGYKP-SDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGK-HEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2B4-1", "uniprot_id": "A0A8M6Z2B4_DANRE", "id": "A0A8M6Z2B4-1", "name": "creatine kinase", "aln": "MG--HINAKLAR-------------------------------LNKQQSAEDEYPDLEHHHN--HMAKVLTLDMYKRLRQRCTPSG-FTIDNVIQTGVDNPGHPFIMTVGCVAGDEETYEVFKELLDPVIQDRHGGYKP-TDKHKTDLNPSNLKGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAVEKLSVQALGALAGDLKGKYYALKNMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDSKTFLVWVNEEDHLRVISMQKGGKMKEVFTRFCIGLTKIEELFRNKGHAFMWNEHLGYVLTCPSNLGTGLRAGVHVKLPNLSK-YRQFEEILKRLRLQKRGTGGVDTAAVGGVFDISNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQSVDDLMPAQK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00564-1", "uniprot_id": "KCRM_RAT", "id": "P00564-1", "name": "Creatine kinase M-type", "aln": "MP--FGNTHNK--------------------------------FKLNYKPQEEYPDLSKHNN--HMAKVLTPDLYNKLRDKETPSG-FTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGYKP-TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLANLSK-HPKFEEILTRLRLQKRGTGGVDTAAVGAVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07310-1", "uniprot_id": "KCRM_MOUSE", "id": "P07310-1", "name": "Creatine kinase M-type", "aln": "MP--FGNTHNK--------------------------------FKLNYKPQEEYPDLSKHNN--HMAKVLTPDLYNKLRDKETPSG-FTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGYKP-TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLANLSK-HPKFEEILTRLRLQKRGTGGVDTAAVGAVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06732-1", "uniprot_id": "KCRM_HUMAN", "id": "P06732-1", "name": "Creatine kinase M-type", "aln": "MP--FGNTHNK--------------------------------FKLNYKPEEEYPDLSKHNN--HMAKVLTLELYKKLRDKETPSG-FTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLAHLSK-HPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BHA3-1", "uniprot_id": "A2BHA3_DANRE", "id": "A2BHA3-1", "name": "creatine kinase", "aln": "MP--FGNTHNN--------------------------------FKLNYSVDEEYPDLSKHNN--HMAKVLTKEMYGKLRDKQTSTG-FTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKDLFDPVISDRHGGYKA-TDKHKTDLNFENLKGGDDLDPNYVLSSRVRTGRSIKGYALPPHNSRGERRAVEKLSVEALSSLDGEFKGKYYPLKSMTDAEQEQLIADHFLFDKPVSPLLLAAGMARDWPDARGIWHNENKTFLVWVNEEDHLRVISMQKGGNMKEVFKRFCVGLQRIEEIFKKHNHGFMWNEHLGFVLTCPSNLGTGLRGGVHVKLPKLST-HAKFEEILTRLRLQKRGTGGVDTASVGGVFDISNADRIGSSEVEQVQCVVDGVKLMVEMEKKLEKGESIDSMIPAQK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09605-1", "uniprot_id": "KCRS_RAT", "id": "P09605-1", "name": "Creatine kinase S-type, mitochondrial", "aln": "MASAFSKLLTGRNASLLFTTLGTSALTTGYLLNRQKVSADAREQHKLFPPSADYPDLRKHNN--CMAECLTPTIYAKLRNKMTPSG-YTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRLMKHPADLDASKITHG-QFDERYVLSSRVRTGRSIRGLSLPPACSRAERREVENVAITALGGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK-DPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P8J7-1", "uniprot_id": "KCRS_MOUSE", "id": "Q6P8J7-1", "name": "Creatine kinase S-type, mitochondrial", "aln": "MASAFSKLLTGRNASLLFTTLGTSALTTGYLLNRQKVSADAREQHKLFPPSADYPDLRKHNN--CMAECLTPTIYAKLRNKMTPSG-YTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHPTDLDASKITHG-QFDERYVLSSRVRTGRSIRGLSLPPACSRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK-DPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17540-1", "uniprot_id": "KCRS_HUMAN", "id": "P17540-1", "name": "Creatine kinase S-type, mitochondrial", "aln": "MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNN--CMAECLTPAIYAKLRNKVTPNG-YTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQG-QFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSK-DPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IFJ7-1", "uniprot_id": "A0A0R4IFJ7_DANRE", "id": "A0A0R4IFJ7-1", "name": "Creatine kinase S-type, mitochondrial", "aln": "MAGSIGKMMSSRTTGLLMASLGAGALATGYMMS-DSAAISADEKRKLYPPSADFPDLRKHNN--CMASALTPAIYAKLRDKLTPNN-WTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFAEIFDPVIKDRHNGYDPRNMKHPTDLDASKLHSG-MFDEHYVLSSRVRTGRSIRGLSLPPACSRAERREVERVVIQALAGLKGDLSGRYYSLTEMTDHEQQRLIDEHFLFDKPVSPLLTASGMARDWPDARGIWHNNEKTFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKQVEHLIQERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVRLPKLSK-DPRFGKILDNLRLQKRGTGGVDTAAVGDTFDISNLDRLGKSEVELVQLVVDGVNYLIECEKRLEKGQDIKVPAPLQQFKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25809-1", "uniprot_id": "KCRU_RAT", "id": "P25809-1", "name": "Creatine kinase U-type, mitochondrial", "aln": "MAGPFSRLLSARPGLKLLALAGAGSLAAGILLRPESVRAATGERRRLYPPSAEYPDLRKHNN--CMASHLTPAVYARLCDKTTPTG-WTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRTMKHTTDLDASKIRSG-YFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKKVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVKLPLLSK-DSRFPKILENLRLQKRGTGGVDTPATADVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLEKGQDIRIPPPLVHGKH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30275-1", "uniprot_id": "KCRU_MOUSE", "id": "P30275-1", "name": "Creatine kinase U-type, mitochondrial", "aln": "MAGPFSRLLSARPGLRLLALAGAGSLTAGILLRPESVGAAAAERRRLYPPSAEYPDLRKHNN--CMASHLTPAVYARLCDKTTPTG-WTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRTMKHTTDLDASKIRSG-YFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSK-DNRFPKILENLRLQKRGTGGVDTAATGSVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPPPLVHSKH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12532-1", "uniprot_id": "KCRU_HUMAN", "id": "P12532-1", "name": "Creatine kinase U-type, mitochondrial", "aln": "MAGPFSRLLSARPGLRLLALAGAGSLAAGFLLRPEPVRAAS-ERRRLYPPSAEYPDLRKHNN--CMASHLTPAVYARLCDKTTPTG-WTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSG-YFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSK-DSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48610-1", "uniprot_id": "KARG_DROME", "id": "P48610-1", "name": "Arginine kinase 1", "aln": "-------MVDA---------------------------------AVLAKLEEGYAKLAASDSKSLLKKYLTKEVFDNLKNKVTPTFKSTLLDVIQSGLENHDS----GVGIYAPDAEAYTVFADLFDPIIEDYHGGFKKTDKHPASNFGDVSTFGNVDPTNEYVISTRVRCGRSMQGYPFNPCLTEAQYKEMESKVSSTLSGLEGELKGKFYPLTGMEKAVQQQLIDDHFLFKE-GDRFLQAANACRFWPSGRGIYHNDAKTFLVWCNEEDHLRIISMQQGGDLGQIYKRLVTAVNEIEKRVP-----FSHDDRLGFLTFCPTNLGTTIRASVHIKVPKLASNKAKLEEVAAKYNLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFEAVKEMYDGITELIKLEKSL------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :..* .. : . ** :: .* : *.. *: : **:*::* . ** * * *:* ** :::**:*. *.*:. . :::. . . .**:*:*** ***::* : * :..: : :* :* .* *:: *::* *. * . *::** :****.: . :* .:. .* **..***:** *:**:* ***** *:***::**.: .:: *: .: .:* . * : :**:: **:**** :*..**:::. *.. :: :: . .** *** * .* : . .:*:** *:* :*.* *: : **:. ::. *: * ", "identical_positions": 107, "similar_positions": 123, "identity": "25.24%" }, { "cls_id": "homologset.agr.FB:FBgn0000117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35222-1", "uniprot_id": "CTNB1_HUMAN", "id": "P35222-1", "name": "Catenin beta-1", "aln": "---MATQADLMELDMAMEP-------DRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQR-RTSMG--GTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGL-----DIGAQGEPLG--YRQDDPSYRSFHSG----GYGQDALGMDPMMEHEMG--------GHHPGADYPVDGLP-------------------------------DLGHAQDLMDGLPPGDSNQLAWFDTDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02248-1", "uniprot_id": "CTNB1_MOUSE", "id": "Q02248-1", "name": "Catenin beta-1", "aln": "---MATQADLMELDMAMEP-------DRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQR-RTSMG--GTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGL-----DIGAQGEALG--YRQDDPSYRSFHSG----GYGQDALGMDPMMEHEMG--------GHHPGADYPVDGLP-------------------------------DLGHAQDLMDGLPPGDSNQLAWFDTDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WU82-1", "uniprot_id": "CTNB1_RAT", "id": "Q9WU82-1", "name": "Catenin beta-1", "aln": "---MATQADLMELDMAMEP-------DRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGPHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQR-RTSMG--GTQQ--QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGL-----DIGAQGEALG--YRQDDPSYRSFHSG----GYGQDALGMDPMMEHEMG--------GHHPGADYPVDGLP-------------------------------DLGHAQDLMDGLPPGDSNQLAWFDTDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QGH7-1", "uniprot_id": "CTNB1_DANRE", "id": "F1QGH7-1", "name": "Catenin beta-1", "aln": "---MATQSDLMELEMAMDP-------DRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEDDDVDN-QVLYEWEQGFNQSFNQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDSAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTSGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQR-RTSMG--GTQQ--QFVEGVRMEEIVEGCTGALHILARDIHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMTWNETGDLGL-----DIGAQGEPLG--YRQDDPSYRSFHSG----GYGQDAMGMDPMMEHEMA--------GHHPGPDYPVDGLP-------------------------------DLGHTQDLIDGLPPGDSNQLAWFDTDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18824-1", "uniprot_id": "ARM_DROME", "id": "P18824-1", "name": "Armadillo segment polarity protein", "aln": "MSYMPAQNRTMSHNNQYNPPDLPPMVSAKEQTLMWQQNSYLGDSGIHSGAVTQVPSLSGK---EDEEMEGDPLMFDLDTGFPQNFTQDQVDDMNQQLSQTRSQRVRAAMFPETLEEGIEIPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELATRAIPELIKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLESTKAAVGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVTLLQRNNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMRSYDYEKLLWTTSRVLKVLSVCSSNKPAIVDAGGMQALAMHLGNMSPRLVQNCLWTLRNLSDAATKVEGLEALLQSLVQVLGSTDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDALVRTIINAGDREEITEPAVCALRHLTSRHVDSELAQNAVRLNYGLSVIVKLLHPPSRWPLIKAVIGLIRNLALCPANHAPLREHGAIHHLVRLLMRAFQDTERQRSSIATTGSQQPSAYADGVRMEEIVEGTVGALHILARESHNRALIRQQSVIPIFVRLLFNEIENIQRVAAGVLCELAADKEGAEIIEQEGATGPLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSIELTNSLLREDNNIWAN-ADLGMGPDLQDMLGPEEAYEGLYGQGPPSVHSSHGGRAFHQQGYDTLPIDSMQGLEISSPVGGGGAGGAPGNGGAVGGASGGGGNIGAIPPSGAPTSPYSMDMDVGEIDAGALNFDLDAMPTPPNDNNNLAAWYDTDC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6P0K8-1", "uniprot_id": "PLAK_RAT", "id": "Q6P0K8-1", "name": "Junction plakoglobin", "aln": "-----------MEVMNLIE--------QPIKVTEWQQT-YTYDSGIHSGVNTCVPSVSSKGLLDEDDTCGRQYTLKKTTTYTQGVPQSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLENVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAG----TQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP-------INEPYA-DDMDATYRP---MYSSD-----VPLDPLDMHMDMDGDYP------------------------------------------------------MDTYSDGLRPPYPAADHMLA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02257-1", "uniprot_id": "PLAK_MOUSE", "id": "Q02257-1", "name": "Junction plakoglobin", "aln": "-----------MEVMNLIE--------QPIKVTEWQQT-YTYDSGIHSGVNTCVPSVSSKGIMDEDDACGRQYTLKKTTTYTQGVPQNQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAG----TQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP-------INEPYA-DDMDATYRP---MYSSD-----VPLDPLDMHMDLDGDYP------------------------------------------------------MDTYSDGLRPPYPTADHMLA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14923-1", "uniprot_id": "PLAK_HUMAN", "id": "P14923-1", "name": "Junction plakoglobin", "aln": "-----------MEVMNLME--------QPIKVTEWQQT-YTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTTYTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAG----TQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP-------INEPYG-DDMDATYRP---MYSSD-----VPLDPLEMHMDMDGDYP------------------------------------------------------IDTYSDGLRPPYPTADHMLA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PVF7-1", "uniprot_id": "PLAKA_DANRE", "id": "Q9PVF7-1", "name": "Junction plakoglobin a", "aln": "----------MEMHMGEAP--------GSVKVTEWQQSYYGTDSGIHSGATTVR-----------SDDDGTEYSSKK-FTYTTTFTENPAEVESQLNMT-RAQRVRAAMFPETVMEGSVIHSTQIDPSQQTNVQKLAEPSQQLKAAIVHLINYQDDAELATRAIPELTKLLNDEDQLVVNKAAMIVNQLTRKEASRRALMQSPQMVAAVVRAMQNTTDMETTRATASILHNLSHQREGLLAIFKSGGIPALVRMLSSPMDSVLFYAITTLHNLLLHQEGAKMAVRLADGLQRMVPLLKKSNPKFLAITTDCLQLLSYGNQESKLIILANGGPEGLVNIMRTYNYEKLLWTTSRVLKVLSVCPSNKPAIVDAGGMQALGKHLSGSSQRLMQNCLWTLRNLSDAATKQDGMENLLQVLVGLLSADDINMLTCATGVLSNLTCNNTRNKTQVTQSNGVEALIHTILRASSKQDVIEPAVCALRHLTSRHPEAETAQNAVRMHYGIPAIVKLLNQPYHWPVVKAVVGLIRNLALCPANQAPLRDADAIPKLVTLLSKAHQDAQKPGSS-----AQRS--YQDGVRMEEIVEGCTGALHIMARDPMNRGTIASMDTIPLFVQLLYSPLDNVKRVAAGVLCELALDKQSAEIIDAEGASAPLMELLHSSNEGIATYAAAVLYRTAEDKNPDYKKRVSVELTHSLFKHDPEAWEMAHNTV--------MDPVLGDEELDGYGPAGYGGYADG-----MHMD--PLDPEMQDDFR------------------------------------------------------SGMPYNSMARVYHDY-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PS81-1", "uniprot_id": "A0A8M9PS81_DANRE", "id": "A0A8M9PS81-1", "name": "", "aln": "----------MSLQMSEAD--------GAVKVEEWQQSFYTADSGIQSGATTIR-----------DED---ESESRK-YSAG----ESSADMEAQFSLT-RAQRVRAAMFPETLVEGETVLTPQSNPDQPTNVQRLAEPSQLLKTAIVHLINYQDDAELATRAVPELTKLLADDDQVVVNKAALIVNQLTRKEASRRVLMQSPQMVSAVVRAMQNTGDLETARCAASVLHSLSHQREGLLAIFKSGGIPALVRMLSSPMESVLFYAITTLHNLLLHQEGAKMAVRLADGLQRMVPLLKKTNPKFLAITTDCLQLLSYGNQESKLIILANGGPECLVFIMRNYNYEKLLWTTSRVLKVLSVCPSNKPAIVDSGGMQALGQHLTGSSQRLTQNCLWTLRNLSDAATKQEGLDGLLQILVSQLGSDDVNMLTCATGILSNLTCNNARNKALVTQSGGVEALIHAVLRAGEKEDVAEPAVCALRHLTSRHPDAELAQNAVRLHYGIPAITKLLGQPHYWPVVKATVGLIRNLALCPANQAPLRESGAIPRLVNLLLKAHQETQRHGSG-----AQQT--YQDGVRMEEIVEGCTGALHILARDPMNRGEIASMQTIPLFVQLLYSYVENIKRVSAGVLCELALDKQSAEMIDAEGASAPLMELLHSPNEGIATYAAAVLFRISEDKSSDYRKRVSVELTHSLFKHDPAAWDMAHAAMP-------LDPGYIPDDLDVVYPP-YG-YSD------LPMDGLPLEAELHEQYM------------------------------------------------------PEMAYDPRQ-VYPNPL----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *** * ****:**. * .: . *::*** ** * . *. : . : * :*:*:**** ** *:*:**************:*** *** *:* :**.:**::*:**::*****:.:* ***:*:*:**::.*: *:::::.: . **.***:*:***************::*.**::***************:*:*:*******.***:**.**::.* *****.*****:*:************.***: ** ***.* ******************.*******::******. ** . * ** ************.*** :*:: :* ** *. *:*::***:* ******** :** * * .*::**:::::.*..:::: ***:********** ::* ***:**::**:..:.*** * **::**.:************:***:: .* :** ** :*.*:::: :. :*: : :********** .*****:**: ** * ..**:**:**:. ::*::**:******** **:.*: *: ***:.** :**** *** ********:* :*** **:**:*:*** **:: : * . . * :. : : ", "identical_positions": 369, "similar_positions": 167, "identity": "43.57%" }, { "cls_id": "homologset.agr.FB:FBgn0000119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0H3-1", "uniprot_id": "A0A0G2K0H3_RAT", "id": "A0A0G2K0H3-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "------------------------------------------MGAVLRSLLACS--------------FCVLLRAAP----------LLLYANRRDLRLVDATN--GKENATIVVGGLEDAAAVDFVFGHGLIYWSDVSEEAIKRTEFNKTE---------SVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGS--SRFVIINTEIYWPNGLTLDYEERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWTDWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLESGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYVYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMAGYMYWTDWGE-IPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGTIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRS-AEREVIIDQLPDLMGLKATSVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETN---NNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT-NLIESSNMLGLNR-EVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVGG-FVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGGQGFTVVVSSVPNQNLEIQPYDLSIDIYSRYIYWTCEATNVIDVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPVALALDSKLSRLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTR----CSCPMHLVLLQDELSCGEPPTCSPQQFTCFT-------GDIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCAN-GQCVGKHKKCDHNVDCSDRSDELDCYPTEEPAP---QATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSG--PPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHR--SYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSV-----------ATAKGYTSDLNYDSEPVPPPPTPRSQYLSAEENY--ESCPPSPYTERSYSHHLYPPPPSPCTDSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88572-1", "uniprot_id": "LRP6_MOUSE", "id": "O88572-1", "name": "Low-density lipoprotein receptor-related protein 6", "aln": "------------------------------------------MGAVLRSLLACS--------------FCVLLRAAP----------LLLYANRRDLRLVDATN--GKENATIVVGGLEDAAAVDFVFGHGLIYWSDVSEEAIKRTEFNKSE---------SVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGS--SRFVIINTEIYWPNGLTLDYQERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWTDWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLMENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGE-IPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGTIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRS-AEREVIIDQLPDLMGLKATSVHRVIGSNPCAEDNGGCSHLCLYRPQGLRCACPIGFELIGDMKTCIVPEAFLLFSRRADIRRISLETN---NNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT-NLIESSDMLGLNR-EVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVGG-FVCGCPAHYSLNADNRTCSAPSTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNSIRKAHEDGGQGFNVVANSVANQNLEIQPYDLSIDIYSRYIYWTCEATNVIDVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSKLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTR----CSCPMHLVLLQDELSCGEPPTCSPQQFTCFT-------GDIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCAN-GQCVGKHKKCDHSVDCSDRSDELDCYPTEEPAP---QATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHSPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSG--PPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSV-----------ATAKGYTSDVNYDSEPVPPPPTPRSQYLSAEENY--ESCPPSPYTERSYSHHLYPPPPSPCTDSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75581-1", "uniprot_id": "LRP6_HUMAN", "id": "O75581-1", "name": "Low-density lipoprotein receptor-related protein 6", "aln": "------------------------------------------MGAVLRSLLACS--------------FCVLLRAAP----------LLLYANRRDLRLVDATN--GKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEEAIKRTEFNKTE---------SVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGS--SRFIIINSEIYWPNGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWSTHSILACNKYTGEGLREIHSDIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGE-IPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRS-AEREVIIDQLPDLMGLKATNVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETN---NNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT-NLIESSNMLGLNR-EVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQSGWNECASSNGHCSHLCLAVPVGG-FVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAVVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTR----CSCPMHLVLLQDELSCGEPPTCSPQQFTCFT-------GEIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCAN-GQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAP---QATNTVGSVIGVIVTIFVSGTVYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSG--PPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSV-----------ATAKGYTSDLNYDSEPVPPPPTPRSQYLSAEENY--ESCPPSPYTERSYSHHLYPPPPSPCTDSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MAD0-1", "uniprot_id": "F1MAD0_RAT", "id": "F1MAD0-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "------------------------------METAPTRAPPPPPQPLLLLLALCC--------------SLVPAAASP----------LLLFANRRDVRLVDAGG--VKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEKRKEILSALYSPMDIQVLSQERQPHFHTPCEEGNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGE-NPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRQTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVK-ASRDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPHATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-MVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPGG--HRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLILPLHGLRNVKAINYDPLDKFIYWVDGRQN-IKRAKDDGTQPSMLTSPSQ-SLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDRPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACAT-------GEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEADCQDGSDEANCDAVCLPNQFRCAS-GQCVLIKQQCDSFPDCADGSDELMCEINKPPSDDVPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVG-GTPHVPLNFIAPGGSQHGPFPGIPCSKSMMSSVSLVGGRGS-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPSTAR--PYRPYIIRGMAPPTTPCSTDVCDSDYSTSRWKT----------------SKYYLDLNSDSDPYPPPPTPHSQYLSAED-----SCPPSPVTERSY-CHLFPPPPSPCTDSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VN0-1", "uniprot_id": "LRP5_MOUSE", "id": "Q91VN0-1", "name": "Low-density lipoprotein receptor-related protein 5", "aln": "------------------------------METAPTRAPPPPP-PPLLLLVLYC--------------SLVPAAASP----------LLLFANRRDVRLVDAGG--VKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEQRKEILSALYSPMDIQVLSQERQPPFHTPCEEDNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKTGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGE-NPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRKTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVK-ASRDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPRATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-MVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPGG--HRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLVLPLHGLRNVKAINYDPLDKFIYWVDGRQN-IKRAKDDGTQPSMLTSPSQ-SLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDKPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACTT-------GEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEADCQDRSDEANCDAVCLPNQFRCTS-GQCVLIKQQCDSFPDCADGSDELMCEINKPPSDDIPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVG-GAPHVPLNFIAPGGSQHGPFPGIPCSKSVMSSMSLVGGRGS-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNVDVFYSSGIPATAR--PYRPYVIRGMAPPTTPCSTDVCDSDYSTSRWKS----------------SKYYLDLNSDSDPYPPPPTPHSQYLSAED-----SCPPSPGTERSY-CHLFPPPPSPCTDSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75197-1", "uniprot_id": "LRP5_HUMAN", "id": "O75197-1", "name": "Low-density lipoprotein receptor-related protein 5", "aln": "------------------------------MEAAPPGPPWPLLLLLLLLLALCG--------------CPAPAAASP----------LLLFANRRDVRLVDAGG--VKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAVQNVVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKRTGGKRKEILSALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGE-NPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVK-ASRDVIIDQLPDLMGLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-VVIADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCMHNNGQCGQLCLAIPGG--HRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVDGRQN-IKRAKDDGTQPFVLTSLSQ-GQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVNAERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACAT-------GEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQFRCAS-GQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSPAHSSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVS-GTPHVPLNFIAPGGSQHGPFTGIACGKSMMSSVSLMGGRGG-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPATAR--PYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKA----------------SKYYLDLNSDSDPYPPPPTPHSQYLSAED-----SCPPSPATERSY-FHLFPPPPSPCTDSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTJ4-1", "uniprot_id": "F1QTJ4_DANRE", "id": "F1QTJ4-1", "name": "", "aln": "------------------------------MELKPG---ALAMEILLLELLLCC--------------SLTVIRGSP----------LLLFANRRDVRLVDVEV--GRSESAVVVSDLEDAAAVDFLFSEGLIFWTDVSEEAIKQTYYNLSTNSMKEATLGKGQTVVVSGLDSPDGLACDWLGHKLYWTDSETNRIEVANLDGTSRKVLFWQDLDQPRAIALNPSHRYMYWTDWGEEPRIERAGMDGS--NRQIIVQKQIYWPNGLTIDLDEQKLYWADAKLSFIHRANLDGTSREAVVEGSLTHPFALTLYDETLYWTDWQTRSIHACNKHSGEKHREILNGIYSPMDIQVLGQERQPNIQTPCSERNGGCSHLCLLSPIPPFYSCACPTGVKLKEDGKTCRPGAEQVLLLARRTDLRRISLDLPDFTDIVLQVNDIRHAIAIDYDPVEGYVYWTDDELRAIRRARIDGSDAQTLITNEINHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRRVLISENLDEPRAIVLDPINGYMYWTDWGE-LPKIERANLDGTDRVVLLNTSLGWPNGLAIDYIAGKLYWGDAKTDKIEVINVDGTNRMTILEDKLPHIFGFTLLGEYIYWTDWQRRSIERVHIAN-STREVIVEQLPDLMGLKATKVMEAEGTNGCAENNGGCSHLCFHRPQGLSCACPMGLELLSDLRTCVVPEAFLLFTNRADIRSISLGTN---SNDVPIPLTGVKEASALDFDVLENRIYWTDVSTKTISRAFMNGSSVEPVIEFGLDYPEGMAVDWMGRNLYWADTGTNRIEVARLDGQYRQVLVCKDLDNPRSLALDPANGYMYWTEWGGRPRIARAHMDGSNIVTLVDKVGRANGLTIDYIDQRLYWTDLDT-CMIESTNMQGLQR-EIVADDLPHPFGLTQYRDYIYWTDWNLRSIERADKRSGLNRTVVQGHLEYVMDILVFHSSRQDGANDCSQNNGQCAHLCLASPSG--AQCRCASHYTLEANGRNCSSPSSFLLFSQKSSISRMVLGEQ-SPDMILPIHVMKNLRAISFDPLERLVYWVDGRQN-IRRSRDDGTQASTVMTPNS-DHP--KQPHDLSLDPYSRTVYWTCETTNTINIHRMDGHIIGEVLKDDVDKPRAIVVNAEKGYMYFTTVQERSAKIEGASLDGTERESLFTTSLIRPVALALDNKLGKLFWVDADLKRIESSDLSGANRIVLQDSNILQPVGLTVLGDHLYWIDKQQQMIERVDKLTGEKRTRIQGRLQYLTGIHAVQYMETDEFATHPCSRDNGGCSHICIAKGDGTPR----CSCPMHLVLLQNLLSCGEPPTCSSEQFTCAT-------GEIDCIPMAWRCDGIAECADNSDEMNCPICSKLQFQCDKGQCVDIQVRCNGEPDCADGSDEQDCETICLSNQFRCGN-SQCILKKQQCDSFPDCTDESDERFCDFP-PPPNDLPRHTSTIGPVIGIILSVFVMGGMCFVCQRVVCRHYKGPNGGFPHEYIS-GTPHVPLNFIAPTNSQHG--KGISCGKSMMSSVSLMGSSSSGAPLYDRNHVTGASSSSSSSTKGAFYPQMLNPPPSPATDRSLYNAEVFYSSNSPSTTR--SYRPYLMRGVAPPTTPCSTDVCDSDYTTSRWKS----------------NKYYMDLNSDSDPYPPPPTPRSQYMSAEE-----SCPPSPSTERSY-FHLCPPPPSPCTDSS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9D7-1", "uniprot_id": "A1Z9D7_DROME", "id": "A1Z9D7-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "MALEPYTKSAEIEPQLCQVIDNNEDVTTKATKCTKSNSGVGWRQMLIGFLLICFGISNSWQYKNVHMPSSSSLIASPPASAFVNTPATLLFTTRHDIQVANITRPTGGPQIDVIVRDLAEAMAIDFYYAKNLVCWTDSGREIIECAQTNSSALQPLLR--APKQTVISTGLDKPEGLAMDWYTDKIYWTDGEKNRIEVATLDGRYQKVLFWTDLDQPRAVAVVPARKLLIWTDWGEYPKIERASMDGDPLSRMTLVKEHVFWPNGLAVDLKNELIYWTDGKHHFIDVMRLDGSSRRTIVN-NLKYPFSLTFYDDRLYWTDWQRGSLNALDLQTR-ELKELIDTPKAPNSVRAWDPSLQPYEDNPCAHNNGNCSHLCLLATNSQGFSCACPTGVKLIS-ANTCANGSQEMMFIVQRTQISKISLDSPDYTIFPLPLGKVKYAIAIDYDPVEEHIYWSDVETYTIKRAHADGTGVTDFVTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDGTARKVLIYEHLEEPRAIAVAPSLGWMFWSDWNERKPKVERASLDGSERVVLVSENLGWPNGIALDIEAKAIYWCDGKTDKIEVANMDGSGRRVVISDNLKHLFGLSILDDYLYWTDWQRRSIDRAHKITGNNRIVVVDQYPDLMGLKVTRLREVRGQNACAVRNGGCSHLCLNRPRDYVCRCAIDYELANDKRTCVVPAAFLLFSRQEHIGRISIEYNEGNHNDERIPFKDVRDAHALDVSVAERRIYWTDQKSKCIFRAFLNGSYVQRIVDSGLIGPDGIAVDWLANNIYWSDAEARRIEVARLDGSSRRVLLWKGVEEPRSLVLEPRRGYMYWTESP-TDSIRRAAMDGSDLQTIVAGANHAAGLTFDQETRRLYWATQSRPAKIESADWDGKKRQILVGSDMDEPYAVSLYQDYVYWSDWNTGDIERVHKTTGQNRSLVHSGMTYITSLLVFNDKRQTGVNPCKVNNGGCSHLCLAQPGRRGMTCACPTHYQLAKDGVSCIPPRNYIIFSQRNCFGRLLPNTTDCPNIPLPVSG-KNIRAVDYDPITHHIYWIEGRSHSIKRSLANGTKVSLLANSGQ--------PFDLAIDIIGRLLFWTCSQSNSINVTSFLGESVGVIDTGDSEKPRNIAVHAMKRLLFWTDVGSHQAIIR-ARVDGNER-VELAYKLEGVTALALDQQSDMIYYAHG--KRIDAIDINGKNKKTLVSMHISQVINIAALGGFVYWLD-DKTGVERITVN-GERRSAELQRLPQITDIRAVWTPDPKVLRNHTCMHSRTKCSHICIASGEGIARTRDVCSCPKHLMLLEDKENCGAFPACGPDHFTCAAPVSGISDVNKDCIPASWRCDGQKDCPDKSDEVGCPTCRADQFSCQSGECIDKSLVCDGTTNCANGHDEADCCKR--PGEFQCPINKLCISAALLCDGWENCADGADESSDICLQRRMAPATDKRAFMILIGATMITIFSIVYLLQFCRTRIGKSRTEPKD---------DQATDPLSPSTLSKSQRVSKIASVADAVRMSTLNSRNSMNS----YDRNHITGASSSTTNGSSMVAYP--INPPPSPATR----------------SRR--PYRHYKIINQPPPPTPCSTDICDESDSNYTSKSNSNNSNGGATKHSSSSAAACLQYGYDSEPYPPPPTPRSHYHSDVRIVPESSCPPSPSSRSSTYFSPLPPPPSPVQSPSRGFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .:* **::.*:*:::.: : ::. .* :* *:** :... : *:* ..* *: : * : *.:: :** .*:*** ** .*:****.*.*****:.*:* :***** :******:*: *: : ****** *:****.***. .* ::. .::*****::* .:. :**:*.* **. .***: *. :*: .* :**:**: : ******. *: * : : :*: . :* .::. . . ** . * **.******::. : *******:* . ..** *: :::::.:**:: :**** **:* : * : .:::********:* ::**:* * :*:*: **:. .:. :: .***:*:**:********* ****** **:** *::*: *.*:*****.: * * *:*:**.* **:* * *** :* **:. .******:*:* :** *.******* * **: * .::.*:: *:**:::*.:::**********:*.* . * *:::* *******.. : .. * * ** ********: *: * *.:. ** .* :**::* ***:*: : * **: * *: **:..*::* ***..* :.:***** . * * ***:*** :: ::: ** *:*:****:..*:**:*: :.****::***. *:**: :.::.**:*.*:* .*::**** * ** ***:: *:* ..:* .**:* :****: . ***:: * :* ::..*: *:.:: * **:**:**. .***..* :* **::::. : :: .:***:..** * * * .** *.:**** * * *.:** * .. .* .* .:::***: .:.*:: . .*:: **: :*::*:.:**: : :**::.*.: *::: :* : : . *.**::* .* ::***. :* *:: : * :* : .: ::** :.*:. : :::* : .: . *. * :**.** : * **.:*. . :::... :**:: *:.* *: .* . :* * :.:: : :**:* :: :*:: : *: *: ::.*:** . . *.* :.. *****:..*:* .* **** **:**:: .** *:*..::*:* : : **** :***** :* *:*** .** * ** * *:*:* : *:* .:* : ** :* .:*:* *: ** :* * :** : : . ::::* : .*: : . . **. . * . . :*::. .. .. *** *:******::..:. . :* :******** : * .** * .**.******:**.. : : : . **:* ******:*:* * ****** :. * ****** ..* ", "identical_positions": 576, "similar_positions": 494, "identity": "33.22%" }, { "cls_id": "homologset.agr.FB:FBgn0000120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15887-1", "uniprot_id": "ARRS_RAT", "id": "P15887-1", "name": "S-arrestin", "aln": "MAACVKTNKSHVIFKKVSRDKSVTIYLGKRDYIDHVSQVEPVDGVVLVDPELVK-GKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAMSA--PTQLQLSLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAFATDITDAEEDKIPKKSSVRLLIRKVQHAPPEMGPQPCAEASWQFFMSDK-PLHLSVSLSKEIYFHGEPIPVTVTVTNNTEKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQE--KVQPNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLTVS--GFLGELTSSEVATEVPFRLMHPQPED-----------PAKESVQDE--------------NLVFEEFARQNLKDTGENTEGKKDEDAGQDE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20443-1", "uniprot_id": "ARRS_MOUSE", "id": "P20443-1", "name": "S-arrestin", "aln": "MAACGKTNKSHVIFKKVSRDKSVTIYLGKRDYVDHVSQVEPVDGVVLVDPELVK-GKKVYVTLTCAFRYGQEDIDVMGLTFRRDLYFSRVQVYPPVGAMSV--LTQLQESLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAFASDITDPEEDKIPKKSSVRLLIRKVQHAPPEMGPQPSAEASWQFFMSDK-PLNLSVSLSKEIYFHGEPIPVTVTVTNNTDKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQE--KVQPNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLTVS--GFLGELTSSEVATEVPFRLMHPQPED-----------PAKESVQDE--------------NLVFEEFARQNLKDTGENTEGKKDEDAGQDE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29067-1", "uniprot_id": "ARRB2_RAT", "id": "P29067-1", "name": "Beta-arrestin-2", "aln": "----MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLK-DRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPMPNPPR-PPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIE---EKSHKRNSVRLIIRKVQFAPETPGPQPSAETTRHFLMSDRRSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDD--QVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPHDHITLPRPQSAPREIDIPVDTNLIEFDTN-YATDDDIVFEDFARLRLKGMKDDDCDDQFC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YI4-1", "uniprot_id": "ARRB2_MOUSE", "id": "Q91YI4-1", "name": "Beta-arrestin-2", "aln": "----MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLK-DRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPMPNPPR-PPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIE---EKSHKRNSVRLIIRKVQFAPETPGPQPSAETTRHFLMSDRRSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDD--QVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPHDHITLPRPQSAPRETDVPVDTNLIEFDTN-YATDDDIVFEDFARLRLKGMKDDDCDDQFC---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TWF6-1", "uniprot_id": "A0AB32TWF6_DANRE", "id": "A0AB32TWF6-1", "name": "", "aln": "----MGDKAGTRVFKKSSPNCKLTVYLGKRDFVDHLDHVDPVDGVLLIDPEYLK-DRKVFVTLTCAFRYGREDLDVLGLSFRKDLFISSFQAYPPLPDERK-PLSRLQERLLKKLGQNAYPFNFTIPQNLPCSVTLQPGPEDTGKACGVDFEVRAFCAKTVD---EKTHKRNSVRLVIRKVQYAPEKPGPQPMVETTRSFLMSDR-SLHLEASLDKELYYHGEPISVNVHVTNNSTKTVKRVKISVLQVTDVVLYSHDTYSKSVGRQSSRD--QVSSSSTFCKVYTLTPTLSNNREKRGLALDGQLKHEDTNLASSTIVKDVSNKEVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPSEQPNS-RPQSAVPETDVPVDANLIEFETNNFSQDDDFVFEDFARLRLKGMKDEE-DDHFC---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49407-1", "uniprot_id": "ARRB1_HUMAN", "id": "P49407-1", "name": "Beta-arrestin-1", "aln": "----MGDK-GTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLK-ERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK-PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE---EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDK-PLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADD--TVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKE----EPPHREVPENETPVDTNLIELDTN----DDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQP6-1", "uniprot_id": "ARRC_MOUSE", "id": "Q9EQP6-1", "name": "Arrestin-C", "aln": "---------MSTVFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVVLVDPEYLE-GRKLFVRLTCAFRYGRDDLDVIGLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDSGKPCGVDFEVKSFCAENLE---EKIPKSDSVQLVVRKVQFSALEPGPGPSAQTIRSFFLSSQ-PLQLQAWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVVQTTDVVLYSLDKYTKTVFVQEFTE--TVAANSSFSQTFAVTPLLAANCQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVRVNLVVSYGGILGGLPASDVGVELPVILIHPKPSP-----------GERAVATSS-------------EDIVIEEFMQHNSQTQS------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15372-1", "uniprot_id": "ARRA_DROME", "id": "P15372-1", "name": "Phosrestin-2", "aln": "------MVVNFKVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEMIGLRFQKELTLVSQQVCPPQKQDIQ--LTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASDESQPCGVQYFVKIFTGDSDC---DRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPG-ELELEVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPLNPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKLFLGALG-------GELCAELPFILMHPKPSR----------------------------------------KAQLEAEGSIEA----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** * : .::*:.:**::* : *:*:**::::* : :. ::::* *.* ****::* :::** *:::* . * *. : :* *::*** :::** : : *.** ** ..* .:.***:: :: * . :: : .::.* :****.:. * * . . *::* *.*.. :.::::.*** : * : : * : *.::::: * * .:: *:. : .: . : : ..*:: :. :.* * * :: *:*::*.:*::** ***:*:: : :**:*** ::*:* :. * :: .*:*. *:**:* : . : ", "identical_positions": 92, "similar_positions": 139, "identity": "20.96%" }, { "cls_id": "homologset.agr.FB:FBgn0000121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29067-1", "uniprot_id": "ARRB2_RAT", "id": "P29067-1", "name": "Beta-arrestin-2", "aln": "MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPMPNPPRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKVQFAPETPGP-QPSAETTRHFLMSDRRSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDD--QVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANK-EVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPHDHITLPRPQSAPREIDIPVDTNLIEFDTN-YATDDDIVFEDFARLRLKGMKDDDCDDQFC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YI4-1", "uniprot_id": "ARRB2_MOUSE", "id": "Q91YI4-1", "name": "Beta-arrestin-2", "aln": "MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPMPNPPRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKVQFAPETPGP-QPSAETTRHFLMSDRRSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDD--QVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANK-EVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPHDHITLPRPQSAPRETDVPVDTNLIEFDTN-YATDDDIVFEDFARLRLKGMKDDDCDDQFC---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TWF6-1", "uniprot_id": "A0AB32TWF6_DANRE", "id": "A0AB32TWF6-1", "name": "", "aln": "MGDKAGTRVFKKSSPNCKLTVYLGKRDFVDHLDHVDPVDGVLLIDPEYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFISSFQAYPPLPDERKPLSRLQERLLKKLGQNAYPFNFTIPQNLPCSVTLQPGPEDTGKACGVDFEVRAFCAKTVDEKTHKRNSVRLVIRKVQYAPEKPGP-QPMVETTRSFLMSDR-SLHLEASLDKELYYHGEPISVNVHVTNNSTKTVKRVKISVLQVTDVVLYSHDTYSKSVGRQSSRD--QVSSSSTFCKVYTLTPTLSNNREKRGLALDGQLKHEDTNLASSTIVKDVSNK-EVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPSEQPNS-RPQSAVPETDVPVDANLIEFETNNFSQDDDFVFEDFARLRLKGMKDEE-DDHFC---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49407-1", "uniprot_id": "ARRB1_HUMAN", "id": "P49407-1", "name": "Beta-arrestin-1", "aln": "MGDK-GTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP-QPTAETTRQFLMSDK-PLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADD--TVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANR-EILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKE----EPPHREVPENETPVDTNLIELDTN----DDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19107-1", "uniprot_id": "ARRB_DROME", "id": "P19107-1", "name": "Phosrestin-1", "aln": "--MVVSVKVFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRKVFGQLATTYRYGREEDEVMGVKFSKELILCREQIVP-MTNPNMEMTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGDDNGKPLGVEYTIRAFVGDSEDDRQHKRSMVSLVIKKLQYAPLNRGQRLPSSLVSKGFTFSNG-KISLEVTLDREIYYHGEKTAATVQVSNNSKKSVKSIKCFIVQHTEITMVN-AQFSKHVAQLETKEGCPITPGANLTKTFYLIPLAANNKDRHGIALDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVRIKLNCGTLG-------GEMQTDVPFKLLQPAPGT-IEKKRSNAMKKMKSIEQHRNVKGYYQD---DDDNIVFEDFAKMRMNNVNMAD---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:****::** *:*.***:***:**:* ******::::*:***:*:*: *: ::*****: :*:*:.* *:*::. * * .: : :*::*::***.:*:** * :* * *.***** :*.**. **:: ::** ... ::: ***. * *:*:*:*:** * * .:: * :*: : **.:**:*:***** ..*:*:**: *:** :: : * ::: : . :. *. . : ::..:.: *.: : * ::*::::*:****:**.**.******:::: . : **::** *::** . * :: .::** *::* * .: . . *: : **::******: *::.:: . ", "identical_positions": 140, "similar_positions": 143, "identity": "32.41%" }, { "cls_id": "homologset.agr.FB:FBgn0000137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M7F4-1", "uniprot_id": "A0ABK0M7F4_RAT", "id": "A0ABK0M7F4-1", "name": "", "aln": "---------------------------------------MEKCKSAGLLALHS---------------------PLRASPLGALAR--REPCR--------------VSARQDTADCARRR-PCPSLPPGG----------VAEPAF--------------LRQRNERERQRVRCVNEGYARLRQHLPREL------------AGQRLSKVETLRAAIGYIKQLQELLERHRPDLNSDGESK----------------------------------------ASSGA----SPCSSEPEERG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QW46-1", "uniprot_id": "M0QW46_MOUSE", "id": "M0QW46-1", "name": "", "aln": "---------------------------------------MEKRRSAGLLALPS---------------------ALRTAPLGALPG--REPCR--------------VSVRQDAADCARRR-PYSSLPLGG----------VAEPAF--------------LRQRNERERQRVRCVNEGYARLRQHLPREL------------AGQRLSKVETLRAAISYIKQLQELLERHRPDCNSDGESK----------------------------------------ASSGA----SPCS-ESEERS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LUI6-1", "uniprot_id": "F1LUI6_RAT", "id": "F1LUI6-1", "name": "", "aln": "---------------------------------------MNSNFCRALVDRGS--------------PGGIQLGVVAPAGPTPLAA--TEPLGNVP--------FLLYPGHSEPSYYDAYTGVFPYVPFPGAFGVY---DYPFEPAF--------------IQKRNERERQRVKCVNEGYARLRGHLPGAL------------AEKRLSKVETLRAAIRYIKYLQELLS-AAPDGAPPTATSPPP-------------------------------------AHAGHGNALQPPSLVAESSGSSFSPSPFLESEEPSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QWB7-1", "uniprot_id": "ASCL5_MOUSE", "id": "M0QWB7-1", "name": "Achaete-scute homolog 5", "aln": "---------------------------------------MNSNFCRALVDRGP--------------PGGMQLGVVAPAGQTPLAA--TEPLSNVP--------FLLYPGHSEPPYYDAYTGVFPYVPFPGAFGVY---DYPFEPAF--------------IQKRNERERQRVKCVNEGYARLRGHLPGAL------------TEKRLSKVETLRAAIRYIKYLQELLS-ATPDGAPPPATSPPP-------------------------------------AHTGHSNVPQPSSLVAESSGSPFSSSPFLESEEPSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJR7-1", "uniprot_id": "ASCL3_MOUSE", "id": "Q9JJR7-1", "name": "Achaete-scute homolog 3", "aln": "---------------------------------------MDTRSYPSPPDRLSVF------------AESAHLPLSRPFYLDPMVT--VHLCPETPVPASYTDELPLLPFSSDTLIMNNYGDPYP-FPFPMPYTNYRRCDYTYGPAF--------------IRKRNERERQRVKCVNEGYARLRRHLPEDY------------LEKRLSKVETLRAAIKYISYLQSLL---YPD-ESETKKNPRT-------------------------------------ASCGS---LDPALRVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09775-1", "uniprot_id": "AST8_DROME", "id": "P09775-1", "name": "Achaete-scute complex protein T8", "aln": "MAALSFSPSPPPKENPKENPNPGIKTTLKPFGKITVHNVLSESGANALQQHIANQNTIIRKIRDFGMLGAVQSAAASTTNTTPISSQRKRPLGESQKQNRHNQQNQQLSKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKGLPL-PQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSGSGDDSFMFIKDEFDCLD-------------------EHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRSPVPQKVVRSPCSSPVSPVASTELLLQTQTCATPLQQQVIKQEYVSTNISSSSNAQTSPQQQQQVQNLGSSPILPAFYDQEPVSFYDNVVLPGFKKEFSDILQQDQPNNTTAGCLSDESMIDAIDWWEAHAPKSNGACTNLSV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19360-1", "uniprot_id": "ASCL2_RAT", "id": "P19360-1", "name": "Achaete-scute homolog 2", "aln": "----------------------------------MESHFNWYGVPRLQKASDA-----CPRESCSSALPEAREGANVHFPPHPVPREHFSCGAPKPVAGAPALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPELLRCSRRRRS---GATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGG------------ANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALSGGLLTPATRPSDVCTQPSASPASASLSCTSTSP--DRLGCSEPASPRSAYSSEDSSCEGETYPMG-QMFDFSNWLGGY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35885-1", "uniprot_id": "ASCL2_MOUSE", "id": "O35885-1", "name": "Achaete-scute homolog 2", "aln": "----------------------------------MEAHLDWYGVPGLQEASDA-----CPRESCSSALPEAREGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDGGALPRLMPTSSGVAGACAARRRQASPELLRCSRRRRS---GATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGG------------ANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALAGGLLTPATPPSDECAQPSASPASASLSCASTSPSPDRLGCSEPTSPRSAYSSEESSCEGELSPMEQELLDFSSWLGGY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99929-1", "uniprot_id": "ASCL2_HUMAN", "id": "Q99929-1", "name": "Achaete-scute homolog 2", "aln": "-----------------------------------------------------------------------------------------------------------MDGGTLPRSAPPAPPVPVGCAARRRPASPELLRCSRRRRP---ATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGG------------ASKKLSKVETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSP--GRGGSSEPGSPRSAYSSDDSGCEGALSPAERELLDFSSWLGGY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19359-1", "uniprot_id": "ASCL1_RAT", "id": "P19359-1", "name": "Achaete-scute homolog 1", "aln": "----------------------------------MESSGKMESG-AGQQPQPP--QPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQAPQQQAPQLSPVADGQPSGGGHKSAAKQVK--------RQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGA------------ANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLN-----------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02067-1", "uniprot_id": "ASCL1_MOUSE", "id": "Q02067-1", "name": "Achaete-scute homolog 1", "aln": "----------------------------------MESSGKMESG-AGQQPQPP--QPFLPPAACFFAT-AAAAAAAAAAAAQSAQQQQPQ-APPQQAPQLSPVADSQPSGGGHKSAAKQVK--------RQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGA------------ANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLN-----------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50553-1", "uniprot_id": "ASCL1_HUMAN", "id": "P50553-1", "name": "Achaete-scute homolog 1", "aln": "----------------------------------MESSAKMESGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVK--------RQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGA------------ANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLN-----------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90260-1", "uniprot_id": "ASL1B_DANRE", "id": "Q90260-1", "name": "Achaete-scute homolog 1b", "aln": "------------------------------------------------------------------------MEATVVATTQLTQDSFYQ-----------PFSESLEK---QDRECKVLK--------RQRSSSPELLRCKRRLTFNGLGYTIPQQQPMAVARRNERERNRVKQVNMGFQTLRQHVPNGA------------ANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAVLQCGVPSPSVSNAYS---------------------------AGPESPHSAYSSDEGSYE-HLSSEEQELLDFTTWFDRYESGASMATKDWC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :** ***:**: ** *: ** ::* :::******* *: ** *: ** . . ", "identical_positions": 26, "similar_positions": 14, "identity": "5.14%" }, { "cls_id": "homologset.agr.FB:FBgn0000139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT90-1", "uniprot_id": "A0A0G2JT90_RAT", "id": "A0A0G2JT90-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAATGVGPGPGVGAGSGPGAAASATTTEDRETEPATAG----AGEGPSAAPGAEPSSGEAESGDANLVDVSG-LETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF--TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSASGNLNGGATLGGGIAAGSSGKGRGAKRKQQ--DGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPSFKYPPKDVTYHP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X20-1", "uniprot_id": "ASH2L_MOUSE", "id": "Q91X20-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAAAGAGPGPGVSAGPGPGAAASATTAEDRETEPVAAG----AGEGPSAAPGAEPSSGEAESGDANLVDVSG-LETESSNGKDTLEGTGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF--TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSASGNLNG------GIAAGSSGKGRGAKRKQQ--DGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYRDIFEGVYFPAISLYKSCTVSINFGPSFKYPPKDLTYHP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBL3-1", "uniprot_id": "ASH2L_HUMAN", "id": "Q9UBL3-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF--TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERD-VFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNG------GIAAGSSGKGRGAKRKQQ--DGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDC-WAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRP--MSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94545-1", "uniprot_id": "ASH2_DROME", "id": "Q94545-1", "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "aln": "--------------------------------------------------------------MEDSQMDTSS--PTESSS-EVNFTAEEDKSQETRSAAGVCYCGKERNLNIVELLCATCSRWVHETCVSYQLGKGKLLPFITNYVFVCKNCSASGLESFRKSQATISQMCHCAIANMQ-QAASRDGRRQIQFSKDKEIIPYIEQYWEAMTTMPRRLTQSWYSTVQRSLVKDVQTLFTYEEHAEHG--------AMYGLFHQDLRIIKPNYESMSKSGALRLTDDG---------YTQASLSKNNRQKRKFPGTDSGPTGKKGRPSSD-ITANVKLPPHGYPLEHPFNKDGYRYILAEPDPHAPFRQEFDESSDWAGKPIPGWLYRILVPHSVLLALHDRAPQLKISEDRLAVTGERGYCMVRATHSVNRGCWYFEVTIEEMPDGAATRLGWGREYGNLQAPLGYDKFGYSWRSRKGTKFTESHGKHYSDAYVEGDTLGFLIELPEEAS-LDYLPNTFKDRPLVKFKSHLYYEDKDKITETLKNLHILQGSRIEFFKNGQSQGVAFEDIYAGSYFPAISIHKSATVSVNFGPAFKYPEVLVEHKAKGMHDRVEELITEQCLADTLYLTEHDGRLRLDNMGL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43132-1", "uniprot_id": "BRE2_YEAST", "id": "P43132-1", "name": "COMPASS component BRE2", "aln": "-----------------------------------------------------------------MKLGIIPYQEGTDIVYKNALQGQQEGKRPNLPQMEATHQIKSSVQGTSYEFVRTEDIPLNRRHFVYRPCSANPFFTILGYGCTEYPFDHSGMSVMDRSEGLSISRDGNDLVSVPDQYGWRTARSDVCIKEG-------MTYWEVEVIRG--GNKKFADGVNNKENADDS-----VDEVQSG------IYEKMHKQVNDTPHLRFGVCRREASLEAPVGFDVYG-------YGIRDISLESIHEGKLN---CVLENGSPLKEGDKIGFLLSLPSIHTQIKQAKEFT-KRRIFALNSHMDTMNEPWREDA--ENGPSRKKLKQETTNKEFQRALLEDIEYNDVVRDQIAIR-YKNQLFFEATDYVKT------TKPEYYSSDKRERQDYYQLEDSYLAIFQNGKYLGKAFENLKPLLPPFSELQYNEKFYLG---YWQHGEARDESNDKNTTSAKKKKQQQKKKKGLILRN-----KYVNNNKLGYYPTISCFNGGTARIISEEDKLEYLDQIRSAYCVDGNSKVNT-----------------LDTLYKEQIAEDIVWDIIDELEQIALQQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : . : .. . : . . : ... : : .* ** : :.:. . :..: * : : . :.:. *** . . .: . : .. : . :. : * :* : . * : . . : * . . .* : **. :::. : * *:* . . : .. . * * : . . ** : .: *:::: :. :..*:. *. . : . . * .: : .. * : .*: . .. . : :*.. : * : ..: . . ..: *.: * *. * .: : :. : . * ::.* : :: .* : . . .:* : :.*. : * : * : ", "identical_positions": 40, "similar_positions": 151, "identity": "6.23%" }, { "cls_id": "homologset.agr.FB:FBgn0000140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZQ1-1", "uniprot_id": "D3ZZQ1_RAT", "id": "D3ZZQ1-1", "name": "", "aln": "MATVQAAYSSEESGRRARRDPA--------AEDASPPVLLLSHFCAVPFLCFGDVRVGTSRTRSLVLHNPHAEPLHVELSLLRAAGQGFSASPNRCELQPKEKITISVTWTPLKEGGVREIVTFLVNDFLKHQAVLLGNAEEQRKKKRSLWNTS--KKIPASSKYTKRTSKN--QNFNESFTISQKV----DRIRSPLQPCENLAMSECCSPTENSSLPLEENKVPTSSISPIR-ECQSEACLSLFSPGPTAYSSLHESENARNSKVQDASISKNFDFNEEVTNETFINPISVSHHS-----------EGDSKLALTPNCSSPLNIAQTQMHFLSPDSFENDSYTSDNGLRSMKNVLSDTFKKDPSESVCLESQTVHEVCQTILSPESFLNDNYGLKKGLNLESVNPVLSPTQFVKDNMVHVG--QQMGELSP-----LPAKPSQDRRVNEGLADNPKGQHAQTPSSKSEQQNPGEMNLHNYGFTKQK-PKISELQDAFCNQSKQLKKRRPILSATVTKRKPTNAREKLPEINKPNAKRSLEGVVGECGKEVDKLKEK-AFHSSLPVVEAVINKPPS---YRNEVTP--STVVIARKRKSS----GTVGDTSGKLAVAEWMDVCEIKRIHFSPLESTPSTVARTTKKEALTSNR----ISNLERSGLKKKTDSSILKTPLSKTKRKRRSIVPVAQSHLTFIKPLKAAIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNYILTPDDFTVKTNVSKVNAATLILGAEGQHKVSVPKAPTKEEVSLRAYTASCRLNRLRRTACSLFTSEKMVKAIKKIEIEIEVGRLLVRKDRHLWKDIGQRQKVLNWLLSYNPLWLRIGLETVFGELIPLADNSDITGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDHAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLSGEGDLSRHLSLLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVRTIELLTQNWNLSDKLRIPAISRVQKMHNVDLVLQVLKSRGVSLTDEHGNTILSKDIVDRHREKTLGLLWKIAFAFQVDISLNLNQLKEEIDFLKHTHNIKTAMSALICSSPAVTKKQKDRRFSGNFEHYGDSVKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPGYVPFDAICQRTTQSVACTQTGSVVLNSSSESEGGCLDLSLEALDHESTPEMYKELLENEKKNFHLVRSAARDLGGIPAMIHHADMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQITWRKYKLKRDLKDRQERDKAARIIQAVVLNFLTRRRLQKRVSAALVIQTCWRRVSAQRKLLMLKNEKLAKLHSASASLIQAHWRRHSTRKHFLKLKHCSVILQSRLRMKIALTSYKRYRWATVTIQRRWRAHLSRKRDQQRFRKLKSASLVIQSVFRRWKRRKLQLQTKAAVTLQRAFREWRCRKQTRE--RAAVVIQSWYR----MHRELQKYIYIRSCVVVIQRRVRCFHAQKLCKRRKDAVLTLQKHFRARQMGKLARTDYLQKRAAAIQLQAAFRGMKARRSYRLQIQAACVLQSYWRMRQGRVKFLNLKKTVIKLQAHIRKHQQLQKYQKIKKAAVTIQTHFRASISARKSLASYQKTRSSVIVLQSAYRGMQARKTFRRALTSVVKIQSCYRAYISRKKFRSLRNAAVKLQSIVKMKQSRKQYLQVRAAAVFIQRWYRSQ-----KRKESVQVREACIKLQSYFRGCLVRKQMRLQSKAAISLQSYFRMWRVRQRYLKTRKAALVIQTFYSAYRAQVHQRKIFLQVKGAAVCLQAAYRGRRARRQIKQQSTAAVTIQRVFRGHSQRMKYQTVLQSAVKVQRWYRAHKVASDMRIHFLKTREAVVVLQSACRGWQVRQQLRRQHQAAVKIQAAFRMARAQRQYKLVRNAAVVIQQHVRARAAGERQHSEYIRLRHAALVFQATWKGKMLRREIAQRHQCAALIQSYYRMYSQRRKWSLMKTAARQIQVCYRAYRVGKEQRHLYLKTKAAVVILQSAYRGMKARRQITECHKAAVTIQSKFRAYRTQKKYTTCRTSAIIIQRWYRNIKITTQQREAYLTLKRAATKVQAVYRGIQVRRHIQHMYMAATLIKALFKIQQSR--------AAAVIQVRYRAYYLGKIQQEKYLTTLRAIKTLQAGVRGARVRKTLRKMHFAATLIQSYFRRHRQRTYFHRLRKAATVVQQRYRAVKEGSSQFQRYSRLRRSVILVQAAFRGLKARRHLKAMHLAATVIQRRFRTLLMRRKFLSLRKTVIWIQRQYRARLHAKYCRQQLLLEK-AVTKIQSSYKGWMVRKSVQKMHRAATVIQATFRMHRACVRYQRLKRASVVIQKQYRAHRTAELQRQLFVRQRQAALTLQAAFRGVKARNHLKTMHASATLIQSKFRARIVRRQFLALRKAAIFVQRKYRATLYAKHKLHQFLQLRKAAITIQSSFRRLMVKKQLQERHRAAALIQATFRMHRTYVRFHLWKRASIRIQQHYRTYRTRKLQREQLSREE----------------------HRAAVRIQSTYRMHRQRCVYQQLRWAAKVIQKKYRANKRRQ---DLPMACKEETPLTQMHFQGSNMAKQVQLQHDAAVIIQKHFRAFKARR------------------------------------------------------------------------------------LVEAERG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQAVWRTSEARQDLRRGEAACRIQAWYRRCRVRRRYLTLLKAVKTIQGYFYAKQERTRFLKMRAAAIIIQRKWRAALCARAACESL----------------------TLKRHGAACVIQAHFRGYKGRQSFRQQRSAALTIQRYVRASVAARQERTKYVQFKKSAVVLQALVRGWLARKRVSEQKANIRRFRFIAAAYCHMCALRIQRAYRRHVAMRNAKKHVNSVIVIQRWFRRRLQQQRFIEQYRKIMAAERDVQARRHQQDRAASVIQKAVRRFLLSRRQQKVNSSATRIQALWRGYASRKKNDRTEIKAIRQSLRAVSRNVEEENKLYRRTERALHHLLTYKHLSAILEAMKHLEVVTRLSPLCCENMAESGAVSTVFVVIRSCNRSVPCMEVVGCAVQVLLNVAKYDKTISAVYDAENCVDTLLELLQAYREKPGDRVAEKSASIFTRTCCLLAVLLKTEQC---AFDAQSRSKVIDRIYRLYKFTVPKHKVNTQGLFDKQKQNSCIGFPFIPERS-IKTRIVSRLKPQWVLRRDNMEEITNSLQAIQLVMDTLGIPYC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ27-1", "uniprot_id": "ASPM_MOUSE", "id": "Q8CJ27-1", "name": "Abnormal spindle-like microcephaly-associated protein homolog", "aln": "MATMQAASCPEERGRRARPDPE--------AGDPSPPVLLLSHFCGVPFLCFGDVRVGTSRTRSLVLHNPHEEPLQVELSLLRAAGQGFSVAPNRCELKPKEKLTISVTWTPLREGGVREIVTFLVNDFLKHQAILLGNAEEPKKKKRSLWNTS--KKIPASSKHTKRTSKN--QHFNESFTISQK-----DRIRSPLQPCENLAMSECSSPTEN--------KVPTPSISPIR-ECQSETCLPLFLRESTAYSSLHESENTQNLKVQDASISQTFDFNEEVANETFINPISVCHQS-----------EGDRKLTLAPNCSSPLNSTQTQIHFLSPDSFVNNRYTSDNDLKSMKNVLSDTFRKDPAESVCLESQTVHEVCQTILSPDSFLNDNYGLKKGLNFKSVNPVLSPTQFVKDSMGHVG--QQTGKSN---------EASQDWRINEGLAYTPECQHAQTPSSRSEKQNPVEVKPHTYDFTKQK-PKISEFQDAFCHQSKQPHKRRPILSATVTKRKPTNAREKLPEINKPDAKRCLEGLVGERGKEVGSLREK-GFHSSLPVVEPGVSKALS---YRDEVTP--ATVVVARKRKSH----GTVGDANGKVAAEEWMDMCEVKRIHFSPLESTPSTVARTTKKEGHTSKR----ISSLERSGLKKKMDSSILKTPLSKTKKKRRSIVAVAQSHLTFIKPLKAAIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNYILTPDDFTVKTNVSKVNAASLVLGAESQHKISVPKAPTKEEVSLRAYTASCRLNRLRRTACSLFTSEKMVKAIKKVEIEIEVGRLLVRKDRHLWKDIGQRQKVLNWLLSYNPLWLRIGLETVFGELIPLADNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDHAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLSGEGDLSRHLSFLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVRTVELLTQNWNLSDKLRIPAISRVQKMHNVDLVLQVLKSRGVPLTDEHGSAISSKDVVDRHREKTLGLLWKIALAFQVDISLNLDQLKEEIDFLKHTHSIKRAMSALTCPSQAITNKQRDKRISGNFERYGDSVQLLMDWVNAVCAFYNKKVENFTVSFSDGRILCYLIHHYHPCYVPFDAICQRTSQSVACAQTGSVVLNSSSESEGGCLDLSLEALDHESTPEMYKELLENEKKNFHLVRSAARDLGGIPAMIHHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLWATVTIQRHWRAYLSRKRDQQIFRKLKSSSLVIQFMFRRWKRRKLQLQTKAAVTLQRAFREWHLRKQIRE--RSAVVIQSWYR----MHRELQKYIYIRSCVIVIQRRVRCFQAQKLYKRRKDAILTLQKHYRARQKGKLAHADYLQKRAATIRLQAAFRGMKARHSYRLQIGAACVLQSYWRMRQERVRFLNLKKMVIKLQAHIRKYQQLQKYKKIKKAAITIQTHFRASISARRVLASYQKTRSSVIVLQSACRGMQARKAFRHALASVIKIQSYYRAYICRKTFQNFKNATIKLQSIVKMKQSRKQYLQIRAAALFIQRWYRSQKLASQKRKEYIQVRESCIKLQSHFRGCLVRKQLRLQCKAAISLQSYFRMRTARQRYLKMCKAALVIQSFYCAYRAQISQRKNFLQVKRAAICLQAAYRGCKVRRQIKQQSTAAVTIQRVFRGHSQRMKYQTMLQSAVKIQRWYRAQKVAYDMRIQFLKTREAVVCLQSAYRGWQVRQQLRRQHEAAVKIQSTFRMAVAQQQYKLLRAAAAVIQQHVRARAAGKRQHLAYIQLRHAALVFQAAWKGKMLRRQIARQHQCAALIQSYYRMHIQRRKWSIMKTAALQIQLCYRAYKVGKEQRHLYLKTKAAVVTLQSAYRGMKVRKRVAECHKAAVTIQSKFRAYRTQKKYTTYRTSAIVIQRWYRNIKITTQQHQEYLNLRRAAVQVQAAYRGIRVRRRIQHMHMAATLIEAMFKMRQSRVRYLKMRTAALIIQVRYRAYYLGKIQHEKYLRTLKAIKTLQAGVRGARVRRTVRKMHFAATLIQSHFRGHRQQTYFHRLRKAATMVQQRYRAVKEGSAEFQRYSRLRRSVLLIQAAFRGLRTRRHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIWIQRQYRARLYAKYSRQQLLLEK-AVIKIQSSYRGWVVRKRVQKMHRAATVIQATFRMHGAYMRYQHLKRASVVIQ----VHTAAELQ-----RQKHAAVILQAAVRGMKTRSHLKTMHSSATLIQSQFRAFIVRRRFIALRKAAIFVQRKFRATLYAKHKLHQFLQLRKAAITIQSSYRRLMVQKKLQEMHRAAALIQATFRMHRTYVAFHIWKCASIRIQQCYRTYRTIKLQKEKLIREEQ---------------------HSAAVLIQSTYRMYRQRCFYQQRRWAAKVIQKTYRANKRRQ---DLLYVCKEETPLLQMHFQGLNTAKQGRQQHGAAMITQKHFRAFKARR------------------------------------------------------------------------------------LMEAERG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FQAGCRKYKAKKYLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGAREN------------------------LKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTRREAHACWLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRKKNDHTEIKAIRRSLRAVSTTVEEENKLYRRTERALHHLLTYKHLSAILDALKHLEVVTRLSPLCCENMAESGAVSTIFVVIRSCNRSVPCMEVVGYAVQVLLNVAKYDKTIAAVYEAENCVDTLLELLQVYREKPGDRVAEKSASIFTRTCCLLAVLLKTEQC---AFDAQSRSKVTDRIYRLYKFTVPKHKVNTQGLFDKQKQNSCVGFPCIPERT-MKTRLVSRLKPQWVLRRDNVEEITNSLQAIQLVMDTLGISY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZT6-1", "uniprot_id": "ASPM_HUMAN", "id": "Q8IZT6-1", "name": "Abnormal spindle-like microcephaly-associated protein", "aln": "MANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLGASRTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVREIMTFLVNDVLKHQAILLGNAEEQKKKKRSLWDTIKKKKISASTSHNRRVSNI--QNVNKTFSVSQKV----DRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLPLSVRRSTTYSSLHASENRELLNVHSANVSK-VSFNEKAVTETSFNSVNVNGQR-----------GENSKLSLTPNCSSTLNITQSQIHFLSPDSFVNNSHGANNELELVTCLSSDMFMKDNSQPVHLESTIAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNENSQVPQSPEDWRKSEVSPRIPECQGSKSP--KAIFEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHNKQPKRRPILSATVTKRKATCTRENQTEINKPKAKRCLNSAVGEHEKVINNQKEKEDFHSYLPIIDPILSKSKS---YKNEVTPSSTTASVARKRKSD----GSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPISKR----ISNREKLNLKKKTDLSIFRTPISKTNKRTKPIIAVAQSSLTFIKPLKTDIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGELISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEE-NSAIIIQSWYR----MHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCR-QIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQN-AVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQK--VFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFL---------------------MIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNR---ASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYKQKKNSSISIPFIPETP-VRTRIVSRLKPDWVLRRDNMEEITNPLQAIQMVMDTLGIPY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8W4-1", "uniprot_id": "A0A8M2B8W4_DANRE", "id": "A0A8M2B8W4-1", "name": "", "aln": "MSFKVAKSECLDFSPPLDSHCS--RDKSGKENSSSIPVLSLLQFSRAPFVSFGTIKLGSSKSLPLRIENPTDDATATVIVDKISASKGFSVDQMSFTIQPEDSIILTVTWTPVEEGGIRELLCFIANGIVKHQAILLGKAETTKKKKKTLWDSIKSKKGVPAPSKEKKVSTMPIKSVNKTFHVSRQSQYRKDRTSNPLSPLNQNGSRRVNTPSSTPEMP--KPAFITETFDNVHLQKDSPVVVLVPAERLLDTPGKKDAPSSRQIECREITRVLNKTLSPASTPERFRNPLSSGFQSPLPVIGQFVQDKSREPEKLSLSVKDALDVIGSDLSHTVSPPNACSSFDFSDSLESDKPDPGASFR--ARRVISPPVETADPRLTFCVKPNKAIGIASNQDEFRLKALPFSTATVTKSIKVDDTHVPDDPKTFPVN---------SATVVKSKADASVESPGLRKKKTSRRRLLEKTLELSEPSNAESNTSSPDSFSALPVINSDSSPDLPLESKICPVAKKK----------PTLNLSPHDQLLSSISPIRPQVFPSVSNS--PSSSLELSASHFSEKVKPNLLENQFPVQSRTLVQSKKRKSDEFLRGHSEDKSNIQAKKCRAPAQATEKPSQERTLTSRSTSGPQRKAVAPPSSRKFTRFPPKKISPKTAQKDARSVKSANSSTRKTAR-IVAVAQARLTFMKPTQTAIPRHPLPFAAKNMFYDERWIEKQERGFTWWMNYILTPDDFKVATEVTKVNALSLTMGND---KFNIPKAPTKEEMSFRTYTARQRLNRLRRAACKLFTSEAMVKAIQRLELEVEAKRLLVRKDRHLWKDIGERQKVLNWLISYNPLWLRIGLETIYGELISLESNNDVMGLAMFILGRLLWNPDLAAEFRHSKVPHLYRDGHEEALSRFTLKKLILLVCFLDKAKESRLIEHDPCLFCMDAEFKSSKDLLLAFSRDFLSGEGILSRHLSHLGLAVSHVQTPLDEFNFAVKKLAVDLKCGIRLVRVMELFTLDWTLSRKLRIPAISRLQKVHNVDLALQVLKNKGVDLRDEHGANIDSRDIVDGHREKTLNLLWKIIFAFQVEVLLDENQLKEEISFLRKTWRTKQKLASIMANNSVTVSRMKARR---AFEHPSQKVTLLMDWVNAVCEFYSLKAENFTVSFSDGRILCYLIHHYHPGHLHAEEIQQRTTQTIECGHRGRVELNNSS-SDSDCSFENLATMQSESVTVDFRELLENEKSNFQLVNTAVSYLGGVPAMINPEDMSNTIPNEKVVTCYLSFLCARLLDLRNETRAARVIQGAWRRYKLQKDIALMHEKNLAATKIQALARKFILKRRLIRQNKAAVKIQTLWRGYSAREKLRVLKKERHYALQNAAATLIQKTYKAWRVKN-LLKKNRSAFVIQAAFRKWHAKKMLERN-TAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFRKEYMALKSASVRIQAMWRGRAERKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAVVIQRQYRAFRDGQKVHAEYTKIKRAAIILQSAYRGRRIRQELQRKNKAATLIQSVMRAHMCH-----------------------QQFLAQKHAAIVIQQQFRAFTFGRMERSHYMRLRKATITMQAIYRGSKVRQNLKREHQAATVIQAQFRMHKVRIPFVAAKCAAILIQQHYRAYKVGKTVQATYLQMKNAAVVIQSAFRGMKVRNYLRKSHQAAKVIQAHFRGHSQLKKYRRQQWAASVLQQRFRATVTKNAVMKQYAAIKTATICIQSAFRGMVARKQIAEKQKCAKIIQKMYRAYKQRHDYLALRNATIRIQQQYRAVVSARQQHQRYCSLRAAAITLQSSYRGLRARKEINRRQKAATVIQAAYKMYRTRVPFQAMKLASLVIQRQYRCHLLRKKARENFLKLKQSAVAIQAIYRGKLARRDLARRHFAATIIQRKYLAYKQRKCFLTLQAAVIFCQQHYRSILLTRHDRKDYLTKRRAVVAIQASFRGMNVRRQIRREHKAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANKIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQERFRANRIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTLQRHFRANKIMRQEMAALQEKKSAALILQAAYRGMKTRHTLKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANRIMRQEMAALQEKKSAALILQAAYRGMKTRQTLKQMHQAATIVQATYRAYSGRKRYLEMKCAAIDIQQRYRAVNAAKQQRKSYLKVRQGALVLQACYRGRKVRRNLQLQCQAAVLIQSYFRRHKEMVKYQAMKLSAVIIQSHFRSYIQARADRKNYQHLRKSAIVIQAAFRGHSLRRHLARKQEASVIIQASFRMYQQRSAFKKQRWAARVLQQRFRALKLRDEHVCQYQQVRNAAVCLQRYFRGMKGRELAR-RSKAARTIQSFLRMSVQRQRFMKEKAAAIAIQSAYRG-----------------------------------------HFARAQYTRMQAGTVLIQKWYRSRKLVQEDRKRFVAVRQATLTLQSALRGMLVRRLAKRRRAAIKIQSVMRMHIQRKRYVTLRASALKFQAHYRMLVAQRKYRRLQAATVTLQKHYRSHRATLEQRCSYLKTLQN---IKKLQARVRGHIAYKRFQRLRTCAITIQANYRGMIERRRFHQLKECALVIQKHYRAFILCQKERSKFLQLR-----------------------QSAVVIQRAYRAYQKRQNAMKAQAALKIQAWFRGRLARRNYILKQAASATIRRCIQARRQRSKFLAVQHSVRVIQQRWRETLSSRKQHAEFLKLIKSVIYIQALWRGRRLRDSIQKQATAAVKIQSAFRGSIQRRRYHQQRNAAITLQRHFRVLRLARVKEENLRRRHNAAIYIQALWRGWLARQQVKEMAFAARRLRFTAAVYHHLSAIKIQRAVRAHWALKSAKKKISSVLYIQQCFRAKLQRKKYLKDREDIIKTQRAVRSWLHRRNQAASIIQHAVRKLLFRRRKERLQRGIIRAQALWRGHCSRKLHDTNKVISMRQRLREVNQRVKEEDKLCNKTTTALTYLLGLQNYAFILAALKHLETATRLSPECCERLVESGATHTIFTLIRSCNRSVPSMEIITLSIQVLLNLSKYHRTIDAVYDVDNSVETLLDLLQIYREKAGDKVADKGGSIFTKTCFLLVLLVQDERR---AMEIRRLPKVMDRIRSIYRLTLRKCKMDAERNKVKQKMNTSLNGSFLLQATPRKSKPVARFAPDWVLRRDKMKDIVDPLRAIQILANALAIVP-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC45-1", "uniprot_id": "ASP_DROME", "id": "Q9VC45-1", "name": "Protein abnormal spindle", "aln": "MSAFEITVTPSRLKQKKR------------AEGREPAVVVMAPFSAKAIVQFEDVPITKTARRQVRVLNPSDDDIEVKVMKAIREEHNLSLEWMEHTVPARDEVSMELVWSPVLEVACKETLQLIDNRNFRKEVMIILKSKSNQPVKN------PRKFPTVGKTLQLKSPTGAGKTMKSVVSAAVQQ----KKRMSAAAAPPSKQTWRVTAPSRPAAWAHPPPQAPLVEKNVYKTPQEEPVYISPQPRSLKENLSPMTPGN--LLDVIDNLRFTPLTETRGKGQATIFPDNLAAWPT-------------PTLKGNVKSCANDMRPRRITPDDLEDQPATNKTFDVKHSETINISLDTLDCSRIDGQPHTPLNKTTTIVHATHTRALACIHEEEGPSPPR-----TPTKSAIHDLKRDIKLVG--------------------SPLRKYSESMKDLSLLSPQTKYAIQGSMPNLNEMKIRSIEQNRYYQEQQIQIKAKDLNSSSSSEASLAGQQEFLFN---------HSEILAQSSRFNLHEVGRKSVKGSPVKNPHKRRSHELSFSDAPSNESLYRN----------ETVAISPPKKQR-----VEDTTLPRSAAPANASARSSSAHAWPHAQSKKFKLAQTMSLMKKPATP----------------------RKVRDTSIQPSVKLYDSELYMQTCINPDPFAATTTIDPFLASTMYLDEQAVDRHQADFKKWLNALVSIPADLDADLNNKIDVGKLFNEVR---NKELVVAPTKEEQSMN-YLTKYRLETLRKAAVELFFSEQMRLPCSKVAVYVNKQALRIRSDRNLHLDVVMQRTILELLLCFNPLWLRLGLEVVFGEKIQMQSNRDIVGLSTFILNRLFRN---KCEEQRYSKAYTLTEEYAETIKKHSLQKILFLLLFLDQAKQKRIVKHNPCLFVKKSPHKETKDILLRFSSELLANIGDITRELRRLGYVLQHRQTFLDEFDYAFNNLAVDLRDGVRLTRVMEVILLRDDLTRQLRVPAISRLQRIFNVKLALGALG----EANFQLGGDIAAQDIVDGHREKTLSLLWQLIYKFRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKFHAAATVLQKWWRRHWLHVVIQRR-----------------IRHKELMRRHRAATVIQAVFRGHQMRKYVKLFKTER----------------------------TQAAIILQKFTRRYLAQKQLYQSYHSIITIQRWWRAQQLGRQHRQRFVELREAAIFLQRIWRRRLFAKKLLAAAETARLQRSQ------------------------------------------------------------KQQAAASYIQMQWRSYQLGRIQRQQFLRQRDLIMFVQRRMR-------------------SKWSMLEQR-----------------------KEFQQLKRAAINIQQRWRAKLSMRKCNADYLALRSSVLKVQAYRKATIQMRIDRN---------------------------------------------------------------------HYYSLRKNVICLQQRLR-------------------AIMKMREQRENYLRLRNASILVQKRYRMRQQMIQDRNAYLRTRKCIINVQRRWR--------------------------------------------------------------------------------------------ATLQMRRERKNYLHLQTTTKRIQIKFRAKREMKKQRAEFLQLKKVTLVVQKRRR-------------------ALLQMRKERQEYLHLREVTIKLQRRFHAQKSMRFMRAKYRGTQAAVSCLQMHWRNHLLRK-------------------RERNSFLQLRQAAITLQRRYRARLNMIKQLKSYAQLKQAAITIQTRYR--------------------------------------------------------------------------------------------AKKAMQKQVVLYQKQREAIIKVQRRYRGNLEMRKQIEVYQKQRQAVIRLQKWWRSIRDMR---------------------------------------------------------------------------------------------------------------------------------------------------------------------LCKAGYRRIRLSSLSIQRKWRATVQARRQREIFLSTIRKVRLMQAFIR--------------------------------------------------------------------------------------------ATLLMRQQRREFEMKRRAAVVIQRRFRAR----------------------------------------------CAMLKARQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYQLIQSSVILVQRKFRANRSMK----------------------------------------------QARQEFVQLRTIAVHLQQKFRGKRLMIEQRNCFQLLRCSMPGFQARARGFMARKRFQ-------------------------------------------------------------------------------------ALMTPEMMDLIRQKR------AAKVIQRYWRGYLIRRRQKHQGLLDIRKRIAQLRQEAKAVNSVRCKVQEAVRFLRGRFIASDALAVLSRLDRLSRTVPHLLMWCSEFMST-FCYGIMAQAIRSEVDKQLIERCSRIILNLARYNSTTVNTFQEGGLVTIAQMLLRWCD---------KDSEIFNTLCTLIWVFAHCPKKRKIIHDYMTNPEAIYMVRETKKLVARKEKMKQN----ARKPPPMTSGRYKSQKINFTPCSLPSLEPDFGIIRYSPYTFISSVYAFDTILCKLQIDMF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .*: : *. .:: * : : : : : ** : . : .:* : ..:.: : : *:*: * :* : :: * .:::.::: ::: : *. * . . : .. : .:. . : : .: .. . . . .*: . . . : . . . . . . . . : . . . .. . . . : . . . : : :* . : . : . . : : . . .. . : . : * : * . . .: * : :*. * . .. . :. :. ..: : : * ::* . ** *..*: **: :::: .*. *:* ::: .:::. .* : .: ****** *:. * : **: **::* ** ** * . .:: : :: * :*.**:* *: ::.:*: *:.:******:***. :** * : .* *: **: ***.**: * .* :: . . : : ::.:.:*:*:::*: *** ** .*::.*:**** .: .* :*::** ** ::*:. * ::*.* ** :.* ** :***::*..:*****: *:**.*.:*:: *: :**:*****:*::.**.:.* .* : * * ::*:** ****** ***:: *: : ** ::* **:: *: : : ::.* :. ** ** :* :. : ::*.*: . :.::* * * . : : : ** :* :: : :: :: : :. :* : ::: : :* :: : : .: : * * .: ::*:**: ** ::** : *.* : :.: :*: :. : . . :*: * :* * : ::* * :: * :::* * : : :*: : . :* :* : :::: .: :: ** : ** .:* : *: ..:..* : : :* : : :: .: :* ::. : . : : :. :* :*. *: : :: : : :.* *: ** :: : * :::. :*: :* : ::: : **.*: . :: .. : :.: :* :*. : : : : :: ::: :*:::**. *::: :* : . :*: * :: * :* :: : *: ::*. :** *: : :: :. ::*:::* : *: : : :. .: :*: .* :. : : .** **::.*::. ::: : :: :: * ***: *: :. : :* : : . :.: :. *: .* : * .:.:*: :* * : : : :: .. ** ::: . :::**:::*. * .:: . : **: *...**. * *: :: : . : .:. : ::. * *:. : :* . . : . :. : *:: : * . : ..: *:: : * * ", "identical_positions": 280, "similar_positions": 595, "identity": "7.9%" }, { "cls_id": "homologset.agr.FB:FBgn0000146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTP9-1", "uniprot_id": "D3ZTP9_RAT", "id": "D3ZTP9-1", "name": "Piwi-like protein 1", "aln": "MTGRAR-ARARGRARGQE---------TVQHVGAAAQ--SQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSK-SQELQISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVK--ESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHK-----VTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNH--RLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEV-DDRTEAYLRALQQKVTSDTQI---------VVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLG----KQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASIN-EGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNP----RLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMB7-1", "uniprot_id": "PIWL1_MOUSE", "id": "Q9JMB7-1", "name": "Piwi-like protein 1", "aln": "MTGRAR-ARARGRARGQE---------TVQHVGAAA---SQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSK-SQELQISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVK--ESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHK-----VTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNH--RLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKAIMIEV-DDRTEAYLRALQQKVTSDTQI---------VVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLG----KQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASIN-EGMTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGYNP----RLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96J94-1", "uniprot_id": "PIWL1_HUMAN", "id": "Q96J94-1", "name": "Piwi-like protein 1", "aln": "MTGRAR-ARARGRARGQE---------TAQLVGSTA---SQQPGYIQPRPQPPPAEGELFGRGRQRG-TAGGTAK-SQGLQISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVK--ESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAFDGTILFLPKRLQQK-----VTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPNDPIDIPSH--RLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGMQMRKAIMIEV-DDRTEAYLRVLQQKVTADTQI---------VVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLG----KQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTAGRRSIAGFVASIN-EGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNP----RLTVIVVKKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVX0-1", "uniprot_id": "PIWL1_DANRE", "id": "Q8UVX0-1", "name": "Piwi-like protein 1", "aln": "MTGRAR-ARSRGRGRGQE---------PAAPGAQPPV--SQEAAKP---VVSTPSEGQLVGRGRQKP-APGAMSE-EAMLQISAGFQQVKIGERGGR-RRDFHDSGVHTRQLMEHVK--ESKTGVSGTAIELRANFMRLLSRPMWALYQYHVDYKPPMESRRLRSALLFQHEETLGKAHTFDGAILFLPNKLRNA-----ETVLCSETRNGEKVEITVTLTNELPPSSPVCLQFYNILFRRILRILNMQQIGRHYYNPDDPFNIPQH--RLTIWPGFMTTILQYESSIMLCSDVSHKVLRSETVLDFMYSLRQQCGDQRFPEACTKELVGLIILTKYNNKTYRIDDIAWDHTPNNTFKKGD-TEISFKNYFKSQYGLDITDGNQVLLVSHVKRLGPSGRPPPGPAMLVPEFCYLTGLTDKMRADFNIMKDLASHTRLSPEQREGRINRLISNINRNGDVQNELTTWGLSFENKLLSLNGRVLPSERIIQGGRAFEYNPWTADWSKEMRGLPLISCMSLDNWLMFYTRRNADVAQSLLQTLNKVSGPMGIRMQRAVMIEY-EDRQESLLRALQQNVARETQM---------VVVILPTNRKDKYDCVKKYLCVDCPTPSQCVVSRTIS----KPQALMTVATKIALQMNCKMGGELWSVEIPLRQLMIVGIDCYHDTAAGKRSIGAMVASLN-QGMSRWFSKCVLQNRGQEIIDALKGSLQGALKAYLKYNNSLPSRIIVYRDGVGDGMLQSVVDYEVPQIMQSIKTMGQDYEP----KLSVVVVKKRISSRFFARIDGKIANPPPGTVIDTEVTRPEWYDFFIVSQAVRFGCVAPTHYNVVFDNSGLKPDHMQRLTYKLCHMYYNWQGIVRVPAPCQYAHKLAFLVGQSIHKEPNMNLDDFLYYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CGT6-1", "uniprot_id": "PIWL4_MOUSE", "id": "Q8CGT6-1", "name": "Piwi-like protein 4", "aln": "MSGRAR-VRARGITTGHS---------AREVGRSSR-----------DLMVTSASPGDSEAGG-----GTSVISQ-PYELGVSSGDGGRTFMERRGKGRQDFEELGVCTREKLTHVK--DCKTGSSGIPVRLVTNLFNLDLPQDWQLYQYHVTYSPDLASRRLRIALLYNHSILSDKAKAFDGASLFLSEKLDQK-----VTELTSETQRGETIKITLTLTSKLFPNSPVCIQFFNVIFRKILKNLSMYQIGRNFYKPSEPVEIPQY--KLSLWPGFAISVSHFESKLLFNADVNYKVLRNETVLDFMTDLCLRTGMSCFTEMCHKQLVGLVVLTRYNNKTYRIDDIDWSVKPTQAFQKRDGSEVTYVDYYKQQYDITLSDLNQPVLVSLLKRKR-NDNSEPQMVHLMPELCFLTGLSSQATSDFRLMKAVAEETRLSPVGRQQQLARLVDDIQRNPVARFELETWGLHFGS-QLSLTGRVVPSEKILLQDHTCQP-AFAADWSKDMRSCKVLSSQPLNRWLIVCCNRAEHLIEAFLSCLRRVGGSMGFNVGYPKIIKV-DETPAAFLRAIQVHGDPDVQL---------VMCILPSNQKNYYDSIKKYLSSDCPVPSQCVLTRTLN----KQGTMLSVATKIAMQMTCKLGGELWSVEIPLKSLMVVGIDICRDALNKNVVVVGFVASIN-SRITRWFSRCVLQRTAADIADCLKVCMTGALNRWYRHNHDLPARIVVYRDGVGNGQLKAVLEYEVPQLLKSVTECGSDARSC---RLSVVVVRKRCLLRLFASTDHTVQNPPLGTVVDSEATRPEWYDFYLISQTANRGTVSPTHYNVIYDDNALKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSVHKEPSLELANNLFYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3Z3-1", "uniprot_id": "PIWL3_HUMAN", "id": "Q7Z3Z3-1", "name": "Piwi-like protein 3", "aln": "MPGRAR-TRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIG--GVFQDLVVNTRQDMKHVK--DSKTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNSLLLSRPLKER-----RVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQ-GRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITMKPAEMIEV-DGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCTKCPIPSQCVVKKTLE----KVQAR-TIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIVNRQKSIAGFVASTN-AELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-----LAFIVVKKRINTRFFLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76922-1", "uniprot_id": "AUB_DROME", "id": "O76922-1", "name": "Protein aubergine", "aln": "MNLPPNPVIARGRGRGRK---------PNNVEANRG---------FAPSLGQKSDPSHSEGNQASGGNGGGGDAQVGPSIEKSS-LSAVQMHKSEGDPRGSVRGRRLITDLVYSRPPGMTSKKGVVGTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILG-GYIFDGTNMFCINQFKAVQDSPYVLELVTKSRAGENIEIKIKAVGSVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENF--RMQLWPGYQTSIRQHENDILLCSEICHKVMRTETLYNILSDAIRDSDD--YQSTFKRAVMGMVILTDYNNKTYRIDDVDFQSTPLCKFKTND-GEISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGND-QAIMIIPELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVEIPARVLPPEKILFGNQKIFVCDARADWTNEFRTCSMFKNVHINRWYVITPSRNLRETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQI---------VMVVMRSPNEEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGAPWQVVIPLHGLMTVGFDVCHSPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYFTG----HRNPVPGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLAFLVAESINRAPSAGLQNQLYFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .. . :** :. . . . :: .: : : .. : * : .*.* * : : :* :.: * *:*.: :.* : .** :* :* . *** :: . : : :: : :.*.: .: .... :: *:::*: :. :.: :.* :* . .:: . : :* *: :: :.*..: : ::: :*::* ** ::: . . ::* ::** *******:**: :. .* *:. * :::: :*::.:: : :* :::* ::*::. **::. *: :: :: .***.* * : : . :: * *.: : . :.. .*:: .* .: .**:.: * ::. :. * :. : . .* : : . : : : .: *: *: :: . : *..:*: . . * *** * :.: * ::.**:. **..*: * * * :: * **:* :. . .:**: : :::* : . :: . :. : ** : . :* ::.:*****:* * ::: *. : : . ::.::* ** * * ** ***:* * * ***:::**:.. * *:** ***: * .*..* :* *:: : *:*** * : *** *:*****::**.:*::: *. * *::*", "identical_positions": 154, "similar_positions": 270, "identity": "17.02%" }, { "cls_id": "homologset.agr.FB:FBgn0000147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59241-1", "uniprot_id": "AURKA_RAT", "id": "P59241-1", "name": "Aurora kinase A", "aln": "-------MDRCKENCVSRPVKSTVPFG-PKRVLVTEQIPSQ-----------------HPGSASSGQAQRVLCPSNS-QRVPPQAQKPVAGQKPVL----KQLPAASGPRPASR-LSNPQKSEQPQPAASGNNSEKEQTSIQKTEDSKKRQWTLEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAP-SSRRTTLCGTLDYQPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSSQRLTLAEVLEHPWIKANSSKPPTGHNSKEATSKSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97477-1", "uniprot_id": "AURKA_MOUSE", "id": "P97477-1", "name": "Aurora kinase A", "aln": "-------MDRCKENCVSRPVKTTVPFG-PKRVLVTEQIPSQ-----------------NLGSASSGQAQRVLCPSNS-QRVPSQAQKLGAGQKPAP----KQLPAASVPRPVSR-LNNPQKNEQ--PAASGNDSEKEQASLQKTEDTKKRQWTLEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAP-SSRRTTMCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNASQRLTLAEVLEHPWIKANSSKPPTGHTSKEPTSKSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14965-1", "uniprot_id": "AURKA_HUMAN", "id": "O14965-1", "name": "Aurora kinase A", "aln": "-------MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQ-----------------NPLPVNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL--SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQN-KESASKQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW76-1", "uniprot_id": "AURKB_DANRE", "id": "Q6NW76-1", "name": "Aurora kinase B", "aln": "-------MQN-KENREPR-VQQTPSAG--VGPLRVEMNPDT-----------------HAVSGPG----RVPVKSNS------------------------------------------------------------------------KVLSIDDFDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPNILRFYNYFHDDTRVFLILEYAPRGEMYKELQRY--GRFDDQRTATYMEEVSDALQYCHEKKVIHRDIKPENLLLGYRGELKIADFGWSVHAP-SLRRRTMCGTLDYLPPEMIEGHSHDEKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRLPLRSVMEHPWVKANSRRVLPPVCSSEPH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88445-1", "uniprot_id": "AURKC_MOUSE", "id": "O88445-1", "name": "Aurora kinase C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MEPSTSTRKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH--QKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTP-SLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVREHSRRVLP-C----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AD76-1", "uniprot_id": "D4AD76_RAT", "id": "D4AD76-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------MLEISRL-----------------LVSLGYPVPNLELLCQREQVQEPWTVVKSPSESTSLAT-------------------------------------------GQMEPSTSTKKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIGKEGLEHQLRREVEIQSHLQHPNILRLYNYFYDDSRVYLILEYAPRGELYKELQRN--QKLNQQRTATIIEELSDALIYCHRNKVIHRDLKPENLLLGLKGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGKSYNETVDLWCIGVLCYELLVGKPPFESSTSSETCRRICQVDFRFPSSMPAGAQDLISKLLRHHPSERLSLAQVLKHPWVRKHSQRMLPPCAQMAS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQB9-1", "uniprot_id": "AURKC_HUMAN", "id": "Q9UQB9-1", "name": "Aurora kinase C", "aln": "-----------------------------------MSSPRA-----------------VVQLGKAQPAGEELATANQTAQ--------------------------------------------------------------QPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKS--EKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70126-1", "uniprot_id": "AURKB_MOUSE", "id": "O70126-1", "name": "Aurora kinase B", "aln": "--------MAQKENAYPWPYGSKTSQS------GLNTLSQR-----------------VLRKEPATTSALALVNRFNSQSTAAPGQKLAENKS-QG-------------------------------------------STASQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--RTFDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWVRANSRRVLPPSAL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55099-1", "uniprot_id": "AURKB_RAT", "id": "O55099-1", "name": "Aurora kinase B", "aln": "--------MAQKENVYPWPYGSKTSQS------GLNTLPQR-----------------VLRKEPAVTPAQALMNRSNSQSTAVPGQKLTENK---G-------------------------------------------ATALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--GTFDEQRTATIMEELSDALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHNPSQRLPLEQVSAHPWVRANSRRVLPPSAL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GD4-1", "uniprot_id": "AURKB_HUMAN", "id": "Q96GD4-1", "name": "Aurora kinase B", "aln": "--------MAQKENSYPWPYGRQTAPS------GLSTLPQR-----------------VLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENS------------------------------------------------SGTPDILTRH-FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGF9-1", "uniprot_id": "Q9VGF9_DROME", "id": "Q9VGF9-1", "name": "Aurora kinase", "aln": "MSHPSDHVLRPKENAPHRMPEKSAAVHNMQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGSNSIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELG---AASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEP-NSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPWILAHTQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38991-1", "uniprot_id": "AURK_YEAST", "id": "P38991-1", "name": "Aurora kinase", "aln": "MQRNSLVNIKLNANSPSKKTTTRPNTSRINKPWRISHSPQQRN--------------PNSKIPSPVREKLNRLPVNNKKFLDMESSKIPSPIRKATS---------------------------------------SKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLH--GPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFWENKRL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::*::*: **:****.** .* :. : ***:: * :: : .:::*.***:***: *.* :: : * **:* *::*::** * ::. *: ::: :: : :..** * * . :****:****:*:* . :*::*****: * . * *:***:** .***: : : . :* *.:***.:* :.* .** * ::* :: :* :. * .** :** . * * .: ***: :. ", "identical_positions": 87, "similar_positions": 88, "identity": "20.19%" }, { "cls_id": "homologset.agr.FB:FBgn0000150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01768-1", "uniprot_id": "NDKB_MOUSE", "id": "Q01768-1", "name": "Nucleoside diphosphate kinase B", "aln": "--------------------------MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19804-1", "uniprot_id": "NDKB_RAT", "id": "P19804-1", "name": "Nucleoside diphosphate kinase B", "aln": "--------------------------MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFKPEELIDYKSCAHDWVYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22392-1", "uniprot_id": "NDKB_HUMAN", "id": "P22392-1", "name": "Nucleoside diphosphate kinase B", "aln": "--------------------------MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15532-1", "uniprot_id": "NDKA_MOUSE", "id": "P15532-1", "name": "Nucleoside diphosphate kinase A", "aln": "--------------------------MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQ-----------ASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQNWIYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05982-1", "uniprot_id": "NDKA_RAT", "id": "Q05982-1", "name": "Nucleoside diphosphate kinase A", "aln": "--------------------------MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFIQ-----------ASEDLLKEHYIDLKDRPFFSGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEISLWFQPEELVDYKSCAQNWIYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15531-1", "uniprot_id": "NDKA_HUMAN", "id": "P15531-1", "name": "Nucleoside diphosphate kinase A", "aln": "--------------------------MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQ-----------ASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B3-1", "uniprot_id": "A0AB13A7B3_DANRE", "id": "A0AB13A7B3-1", "name": "Nucleoside diphosphate kinase", "aln": "-------------------------MSAKTERTFIAVKPDGVQRGLMGEIIKRFEQKGFRLVAMKFLQVCVLMVDQDAVASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIEVGRNIIHGSDSVDSANTEISLWFKPEELVSFKSCAQQWIYE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QIK4-1", "uniprot_id": "A0A8M9QIK4_DANRE", "id": "A0A8M9QIK4-1", "name": "Nucleoside diphosphate kinase", "aln": "MGSGVSSPRPPTTPAAQPDKCTTAPMSGNEERTFIAIKPDGVQRGLVGEIIKRFEQKGFKLVAMKLIQ-----------ADEDLLRQHYSDLKDRPFFPGLVSYMSAGPVVAMVWEGFNVIKTGRVMLGETNPIDSKPGTIRGDFCVQVGRNIIHGSDSVESANTEINLWFKPDEICDYTKCQESWINS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08879-1", "uniprot_id": "NDKA_DROME", "id": "P08879-1", "name": "Nucleoside diphosphate kinase", "aln": "-------------------------MAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTW-----------ASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36010-1", "uniprot_id": "NDK_YEAST", "id": "P36010-1", "name": "Nucleoside diphosphate kinase", "aln": "-------------------------MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVK-----------ADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ***** :*********:.:*:.***:**::**.:*: *... *.:** : :**:. :*.:* :**::. **** :*:: ** :** *** .* ******** :::***: ****:*.**: ** ***: .*: : .*: .", "identical_positions": 71, "similar_positions": 49, "identity": "37.57%" }, { "cls_id": "homologset.agr.FB:FBgn0000152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH79-1", "uniprot_id": "ANO10_MOUSE", "id": "Q8BH79-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MRVTLSTLDTCESSFTPLVVIELAQDVKDETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEKETLENQ----NLYLVGASNVRLLLGAEAVGLVKECTDAAMRAFTYGTRHNFKGFHDNNNDFLTMAECQFIIKHELENLRARDEKMIPGY----PQAKLYPGKSLMRRLLTSGIVTQVFPLHDTEALKKLEDTWYTRFALKYQPIDSIRSYFGETIALYFGFLEYFTFALIPMAIIGLPYYLFVWED-----------------------YDKYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPRPGFHGVLGINSVTGREEPLYSSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSEWTSLLLYVPSIVYAVVIEIMNRLYRYAAEFLTSWEN--HRLESAYQN----HLVLKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQVVESLLPYWLQRKYCARVKRK----VQALKSEVDTTLYEQVLLEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFAEPSAS----------IGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPES----------------KTDLVLIVVAVEHALLALKFILAFAIPDKPRHIQQKLARLEFESLEALKQQQMKLVAENLKEEYQEDGKEAT------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LE79-1", "uniprot_id": "A0ABK0LE79_RAT", "id": "A0ABK0LE79-1", "name": "Anoctamin", "aln": "MFSWFLKEKETAERKHWSGSPGSRACRRMPPSRTESSLSALELCGSQGLCHGYPVATSQSCPWETETSSQPYGMELSRLLPLRAPVIIRVGKPHPEAPGRAILSPDSQIEEEEEEAEEEEKKEEERRRRKRKKKKRKKRRKKKRRLLRSKRLSLSKMKGILSTVDTCESSFTPLVVIELAQDVKEETKEWLKSRIISPKKDGGAQLLFRPLLNKYEKETLENQ----NLYLVGASNIRLLLGAEAVGLVKECTDGAMRAFTYRTRHNFKGFHGNNDDFLTMAECQFIIKHELENLRARDEKMIPGY----PQAKLYPGKSLMRRLLTSGIVTQVFPLHDTEALKKLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWED-----------------------YDKYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPRPGFHGVLGINSVTGREEPVYSSYKRQLRTYLVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSEWTSLLLYVPSIVYAIVIEIMNRLYRYAAEFLTSWEN--HRLESAYQN----HLVLKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQVVESLLPYWLQRKYCARVKRK----VRALKSDVDTTLYEQVLLEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSAS----------IGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPES----------------KTDLVLIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVAESLKEESQEEEKEAAACRMPATLPQPELRNNCITPGQGGDASLS-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NW15-1", "uniprot_id": "ANO10_HUMAN", "id": "Q9NW15-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MKVTLSALDTSESSFTPLVVIELAQDVKEETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEQETLENQ----NLYLVGASKIRMLLGAEAVGLVKECNDNTMRAFTYRTRQNFKGFDDNNDDFLTMAECQFIIKHELENLRAKDEKMIPGY----PQAKLYPGKSLLRRLLTSGIVIQVFPLHDSEALKKLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWED-----------------------YDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGVLGINSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWEN--HRLESAYQN----HLILKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQIMESFLPYWLQRKHGVRVKRK----VQALKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYP-LAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSAN----------IGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPES----------------KADLILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEPMESGKEKAT-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8U5-1", "uniprot_id": "ANO10_DANRE", "id": "Q4V8U5-1", "name": "Anoctamin-10", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MQLGLSVSDSDASPFTPLAVLELAHDTKAEAIAWLLNRIRDKQRNGGAELLVDQLLFPAQDGQKPNP----NVFVVGSTLQRLLSGAEDVGLFKEFQDGTMRGFTYANRESFKDFEGDGEGFLGDAECQYIVKHELDTLRAKNEEYIPGY----PKYKLYPGKSIVRRLQSKGVLVQYFPLHNKEDLKRLSFSWYKKIKLSFQPLDDIRSYFGEGLGLYFGFLEYFTFALIPMALIGIPYYLFDWED-----------------------YDKYVLFAVFNLVWSTVFLEVWKRCSATLAYSWGTLGRKKAFEEPRAGFHGPLGLNPVTGREEPIYPSSKRHLRIYLVSVPFVLLCLYLSFYVMMVYFDMEFWAISIYHENPNFATSVLLFVPSIIYAVVIEIMNLLYRYAAEFLTDWEN--HRLESSFQN----HLVPKVLVFNFVNCFASLFYIAFVMQDMVLLRQSLATLLITSQILNQVMEAFLPYWLQRRRNKRVYKR----MRRLMGDKELPLLEQIQLETEMNTYLGTFDDYLEQFLLFGYVSLFSCVHP-LAAVLVVLNNITEVYSDAFKMCHVFKRPFSEPAAN----------IGVWQLAFETMSIIAVVTNCALIALSPQVKAYFPES----------------DAQLILTVVAIEHVLLAFKFILAFVIPDVPKHIQVKLSKLDFESLEALKKRKILEVAET-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P6G3-1", "uniprot_id": "A0A8M9P6G3_DANRE", "id": "A0A8M9P6G3-1", "name": "Anoctamin", "aln": "MAGSRTQIYQTAEQDCSLCWKKNENAPPHPKAREERRSSAFFFSPSKAAHGLDLNRFQTGQWGECGHQQHSPESDRRSRLFDRSQTGFLEG-------------------HSSAQFCSNPNQTQLMQLIKLQRDNMTSQKEPQEGHSTSTKVTGPSSWSKVSCPCCTSTQIEPLVLIQLAESVQPITKQWIMSVIAAPVKAGGAQLLVHP-------GEDMKG----DMIVVAAPRCTLHRVTEELGLCKTYQDGDMKAFSFEDRDNFCNID-DTQQFLTLAERQFIVKHEMDLMKALEDQRIPGIP--APAGKLKARESILQKLEKAGLIRSITPLHDQERLADLGKQWYSQKSLWGQPLDYIHNYFGGTIAYYFSFLDFYTLSLFPPAILGIFITFFLPSANFSTAIETDSNASSKISDDDHLSVSSYMVQAVFSMLWSTIFMELWKRRSASLSYHWGTFNLAEQFQEPRPGFHGEIGTNPVTGRLEPLFPDWKRKMRMGLVSVPVVGFFLGLVILGMAGFYICERLVSSWHKESGSYFTAPLLYLPSIAHIVYTNVLGNVYRNVALKLTEAEN--HREESSFDY----HHTTKVLVFTFFNNFAVLFHIAFFKEDMPLLRKRLSSLLIVTQVVGQFTEVVVPFLVDR----FLTSA----NRNLKED--DPEVDHLQAQGSLPAFPGLFAEYIELLVQFGYLSLFSCVYP-LTAPLLLLNNLTEIRTDAYKLCKLFNKPFSAPVAN----------LGVWQLAFEVLSFISVISNCWLLLLSPRVKEWTQEAGLS-------------SSQVIVIAVIVEHVLLIVKMILAFIIPDEPDWLQVKREQIEYNSMQALKKQRIKSTRVDGKLQKAKMGE---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97132-1", "uniprot_id": "O97132_DROME", "id": "O97132-1", "name": "Anoctamin", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSEDAKSPGPRTRNIIENQLFRRQRSLKLEALQRQRTLDSNDGVEGLGADTEPFDKTHIVIIFTEKAKLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKMTTTHSMQKFNHGCISDFLLPGMGKEQILRYCEIPVLIKDVIQDG--------------------------IKSYVQKGYIEDMFPLHDILYLERFNWNLKR----TKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVFDLNIS---------------------------LVCSFYVVWTTIFLELWKRKCAGYSYRWGTIEMS-SLDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQMYCISYPVVLGCVVAAGWFALYQFQIEAEVLADFGPD-----SWLLYVPVIVQSVLIAIFSWAYEKLATFLTNLEN--HRTRSQYDR----HRVNKLMLFEIVNNFFSQFYIAFVLHDLRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAP-FAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKN----------IGAWQLAFELLSVMSLLSNCGLLFLQPNVKDFFSHWLP---------------SVPDLSFVIFEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKAEANKMA----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38250-1", "uniprot_id": "IST2_YEAST", "id": "P38250-1", "name": "Increased sodium tolerance protein 2", "aln": "----MSQTITSLDPNCVIVFNKTSSANEKSLNVEFKRLNIHSIIEPGHDLQTSYAFIRIHQDNAKPLFSFLQNLDFIESIIPYHDTELSD-------------DLHKLISISKSKILEAPKQYELYNLSNLTNNPKQSLYFAFLQNYIKWLIPFSFFGLSIRFLSNFTYEFNSTYSLFAILWTLSFTAFWLYKYEPFWSDRLSKYSSFSTIEFLQDKQKAQKKASS-VIMLKKCCFIPVALLFGAILLSFQLYCFALEIFIKQIYNGPMISILSFLPTILICTFTPVLTVIYNKYFVEPMTKWENHSSVVNAKKSKEAKNFVIIFLSSYVPLLITLFLYLPMGHLLTAEIRTKVFNAFSILARLPTHDSDFIIDTKRYEDQFFYFIVINQLIQFSMENFVPSLVSIAQQKING-------------PNPNFVKAESEIGKAQLSSSDMKIWSKVKSYQTDPWGATFDLDANFKKLLLQFGYLVMFSTIWPLAPFICLIVNLIVYQVDLRKAVLYSKPEYFPFPIYDKPSSVSNTQKLTVGLWNSVLVMFSILGCVITATLTYMYQSCNIPGVGAHTSIHTNKAWYLANPINHSWINIVLYAVFIEHVSVAIFFLFSSILKSSHDDVANGIVPKHVVNVQNPPKQEVFEKIPSPEFNSNNEK--ELVQRKGSANEKLHQELGEKQPASSANGYEAHAATHANNDPSSLSSASSPSLSSSSSSSKTGVVKAVDNDTAGSAGKKPLATESTEKRNSLVKVPTVGSYGVAGATLPETIPTSKNYYLRFDEDGKSIRDAKSSAESSNATNNNTLGTESKLLPDGDAVDALSRKIDQIPKIAVTGGENNENTQAKDDAATKTPLIKDANIKPVVNAAVNDNQSKVSVATEQTKKTEVSTKNGPSRSISTKETKDSARPSNNNTTTTTTTDATQPHHHHHHHRHRDAGVKNVTNNSKTTESSSSSSAAKEKPKHKKGLLHKLKKKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : * :. * . . : . ::. : : : : : : : . : : : : :. :: : * . : . : : : . * . :* .. :: : : . . :. . . : : . :* : * : : *. . .. * .: : * ::::: .. . : :. : : : :: ::: .: : . : : . * :. * ::: :. * . ::*:: . :* : :* :. :: : :. : : .: .. : : . . :*. . . ", "identical_positions": 17, "similar_positions": 129, "identity": "1.74%" }, { "cls_id": "homologset.agr.FB:FBgn0000157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50575-1", "uniprot_id": "DLX5_RAT", "id": "P50575-1", "name": "Homeobox protein DLX-5", "aln": "-MTG-VFDRRVPSIRSGDFQAPFPTSA---------------------------------AMHHPSQESPTLPESSATDSDYYSPAGAAPHGYCSP--TSASYGKALNPY----QYQYHSVNGSAAGYPAKAYADYG-YASPYHQYGGAYN--RVPSATSQPEKEVAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMK----NGEMPPEHSPSSSDPMACNSPQS--------------------PAVWEPQGSSRSLSHH-------PHAHPPTSNQSPASSYLEN-SASWYPSAAS-SINSHLPPP--------------GSLQHPLALAS---GTLY---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70396-1", "uniprot_id": "DLX5_MOUSE", "id": "P70396-1", "name": "Homeobox protein DLX-5", "aln": "-MTG-VFDRRVPSIRSGDFQAPFPTSA---------------------------------AMHHPSQESPTLPESSATDSDYYSPAGAAPHGYCSP--TSASYGKALNPY----QYQYHGVNGSAAGYPAKAYADYG-YASPYHQYGGAYN--RVPSATSQPEKEVAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMK----NGEMPPEHSPSSSDPMACNSPQS--------------------PAVWEPQGSSRSLSHH-------PHAHPPTSNQSPASSYLEN-SASWYPSAAS-SINSHLPPP--------------GSLQHPLALAS---GTLY---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56178-1", "uniprot_id": "DLX5_HUMAN", "id": "P56178-1", "name": "Homeobox protein DLX-5", "aln": "-MTG-VFDRRVPSIRSGDFQAPFQTSA---------------------------------AMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSP--TSASYGKALNPY----QYQYHGVNGSAGSYPAKAYADYS-YASSYHQYGGAYN--RVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMK----NGEMPPEHSPSSSDPMACNSPQS--------------------PAVWEPQGSSRSLSHH-------PHAHPPTSNQSPASSYLEN-SASWYTSAAS-SINSHLPPP--------------GSLQHPLALAS---GTLY---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50576-1", "uniprot_id": "DLX5A_DANRE", "id": "P50576-1", "name": "Homeobox protein Dlx5a", "aln": "-MTG-VFDRRIPSIKPADFQNPFQLS----------------------------------TMHHPSQESPTLPESTATDSGYYSPAGGVHHGYCSP--NSGTYGKPLNAY----QYQYHGVNGSSGNYSAKSYPDYGSYSTAYHQYAGTYN--RVQSQPSPQEKETAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQNTQYLALPERAELAASLGLTQTQVKIWFQNKRSKLKKIMK----NGELPPEHSPSSSDPMACNSPQS--------------------PAVWDSQGPQR------------PHHQPQNIN-TAASTFLEM-RELFVVFLYRGDEFFTLQAP--------------GTL-HSLALGS---GTLY---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4ADD0-1", "uniprot_id": "D4ADD0_RAT", "id": "D4ADD0-1", "name": "", "aln": "-MSG-SFDRKLSSILT-DISS----SL---------------------------------SCHAGSKDSPTLPESSVTDLGYYSAP---QHDYYS----GQPYGQTVNPYTYHHQFNLNGLAGT-GAYSPKS--EYT-YGGSYRQYG-AYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK----NGEVPLEHSPNNSDSMACNSPPS--------------------PALWDTS-SHSTPAPT-------RNPLPPPLPYSASPNYLDDPTNSWYHTQNLSGPHLQQQPPQ------------PATLHHASPGPPPNPGAVY---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64205-1", "uniprot_id": "DLX3_MOUSE", "id": "Q64205-1", "name": "Homeobox protein DLX-3", "aln": "-MSG-SFDRKLSSILT-DISS----SL---------------------------------SCHAGSKDSPTLPESTVTDLGYYSAP---QHDYYS----GQPYGQTVNPYTYHHQFNLNGLAGT-GAYSPKS--EYT-YGGSYRQYG-AYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK----NGEVPLEHSPNNSDSMACNSPPS--------------------PALWDTS-SHSTPAPA-------RNPLPPPLPYSASPNYLDDPTNSWYHTQNLSGPHLQQQPPQ------------PATLHHASPGPPPNPGAVY---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60479-1", "uniprot_id": "DLX3_HUMAN", "id": "O60479-1", "name": "Homeobox protein DLX-3", "aln": "-MSG-SFDRKLSSILT-DISS----SL---------------------------------SCHAGSKDSPTLPESSVTDLGYYSAP---QHDYYS----GQPYGQTVNPYTYHHQFNLNGLAGT-GAYSPKS--EYT-YGASYRQYG-AYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK----NGEVPLEHSPNNSDSMACNSPPS--------------------PALWDTS-SHSTPAPA-------RSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQ------------PATLHHASPGPPPNPGAVY---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01702-1", "uniprot_id": "DLX3B_DANRE", "id": "Q01702-1", "name": "Homeobox protein Dlx3b", "aln": "-MSGPTYDRKIPGIST-DLSG----SM---------------------------------SCHPTSKDSPTLPESSATDMGYYSS----HHEYYQ----SPPYPQQMNSY---HQFNLSGMGATPGAYPTKT--EYP-YN-TYRQYG-HFN-RDLQTPPQSAVKEEPETEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK----NGEVPLEHSPNASDSMACNSPPS--------------------PAVWDNN-AHSS-QVN-------RGQIPQP-PLSSTPPYMEDYSNHWYQ----QGSHLQHP------------------VHH--PGPPQSVGAVY---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07687-1", "uniprot_id": "DLX2_HUMAN", "id": "Q07687-1", "name": "Homeobox protein DLX-2", "aln": "-MTG-VFDSLVADMHSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSS--------------LHKPQESPTLPVSTATDSSYYTN---QQHPAGGGGGGGSPYAH-MGSY----QYQASGLNNV--PYSAKSSYDLG-YTAAYTSYA-PYG-TSSSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWK----SGEIPSEQHPGASASPPCASPPVS------------------APASWDFGVPQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGN--YPWYHQTSGSASHLQATAPLLHPTQTPQP--HHHHHHHGGGGAPVSAGTIF---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40764-1", "uniprot_id": "DLX2_MOUSE", "id": "P40764-1", "name": "Homeobox protein DLX-2", "aln": "-MTG-VFDSLVADMHSTQITASSTYHQHQQPPSGAGAGPGGNSNSSSSN-----------SSLHKPQESPTLPVSTATDSSYYTN---QQHPAGGGGGGASPYAH-MGSY----QYHASGLNNV--SYSAKSSYDLG-YTAAYTSYA-PYG-TSSSPVNNEPDKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWK----SGEIPTEQHPGASASPPCASPPVS------------------APASWDFGAPQRMAGGG-PGSGGGGAGSSGSSPSSAASAFLGN--YPWYHQASGSASHLQATAPLLHPSQTPQAHHHHHHHHHAGGGAPVSAGTIF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50574-1", "uniprot_id": "DLX2A_DANRE", "id": "P50574-1", "name": "Homeobox protein Dlx2a", "aln": "-MTG-VFDSLSTDMHSNQITSSS-YHS-----------------------------------LHKSQESPTLPVSTATDSSINNN---NQQ------CAGSPYGQ-SSSY----QYQNNSMNSV--QYNTKS-YELG-FGNAFGPYG-TYG-SCSSPTPADAEKEEREPEIRMVNGKPKKVRKPRTIYSTFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWK----SGEIPPEQHVASGESPPHPSPPL--------------------AAAWDFAHSQRMNTVN------SGLSQSS-PPNSTTPSFLTN--YPWYSSTN-SAAHLQP-----------------PLHHN----TTVSAGTIF---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98876-1", "uniprot_id": "DLX2B_DANRE", "id": "Q98876-1", "name": "Homeobox protein Dlx2b", "aln": "-MTA-VLDSLGSDMHTNHITSSS-FST-----------------------------------VHKSQDSPTLPVSTVTDSSFFSS---SQTGH----CAGTAYAQ-LASY----SYHPGTVGNV--HYSPKA-YDLG-YASSYGAYG-TYG-ASSSPTPTEPEKEESEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWK----NGEIPADQQVASGDSP-SSSPPP--------------------QAGWDFPPNPTQNDGD------TVSEQPTGPPNTTAPSFLTN--YSWYSSTN-AVTHLQPST-------------LIQPHHS----SAMSTGTIF---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AMV7-1", "uniprot_id": "A0A8I6AMV7_RAT", "id": "A0A8I6AMV7-1", "name": "Homeobox protein DLX-6", "aln": "MMTMTTMADG---LEGQDSSKSAFMEFGQQQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPQPHSQQTSPA-MAGAHYPLHCLHSAAAAAAAAGSHHHHHQHHHHGSPYASG--GGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTRGDD--TDQQKTTV-IENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLK--QGSNPHESDPLPGSAALS-PRSPA--------------------LPPVWD-------------------VSASAKGVSMPPNSYMPG-YSHWYSSPH-QDTMQRPQMM-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70397-1", "uniprot_id": "DLX6_MOUSE", "id": "P70397-1", "name": "Homeobox protein DLX-6", "aln": "---------------------------------------------------------------------------------------------------------------------------------MSHSQHSPYLQSYHNSSAAAQTRGDD--TDQQKTTV-IENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLK--QGSNPHESDPLPGSAALS-PRSPA--------------------LPPVWD-------------------VSASAKGVSMPPNSYMPG-YSHWYSSPH-QDTMQRPQMM-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56179-1", "uniprot_id": "DLX6_HUMAN", "id": "P56179-1", "name": "Homeobox protein DLX-6", "aln": "---------------------------------------------------------------------------------------------------------------------------------MSHSQHSPYLQSYHNSSAAAQTRGDD--TDQQKTTV-IENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLK--QGSNPHESDPLQGSAALS-PRSPA--------------------LPPVWD-------------------VSASAKGVSMPPNSYMPG-YSHWYSSPH-QDTMQRPQMM-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98877-1", "uniprot_id": "DLX6A_DANRE", "id": "Q98877-1", "name": "Homeobox protein Dlx6a", "aln": "MMTMTTMADG---LEAQDSSKSAFMEFGQQ--------------------------------SHSQQSSPS-MAASHYPLHCLHS--------GSHHHH---QHDSSPYS----GSNSYN-RSLP-YSYVSHPHHSPYLPSYHSNASGTQTRLDA--TEQQKTTV-IENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLK--QGGNPHETDTLPGSIALS-PRSPA--------------------IPPIWD-------------------VSASSKGVNMSANSYMPG-YSHWYSSPH-QDAMQR---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P56177-1", "uniprot_id": "DLX1_HUMAN", "id": "P56177-1", "name": "Homeobox protein DLX-1", "aln": "-MTMTTMPES---LNSPVSGKAVFMEFGPP----------------------------------NQQMSPSPMSHGHYSMHCLHS--------AGHSQPDGAYSSASSFS------RPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTV-VEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK--QGGAALEGSALANGRALS-AGSPP--------------------VPPGWNP------------------NSSSGKGSGGNAGSYIPS-YTSWYPSAH-QEAMQQPQLM-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64317-1", "uniprot_id": "DLX1_MOUSE", "id": "Q64317-1", "name": "Homeobox protein DLX-1", "aln": "-MTMTTMPES---LNSPVSGKAVFMEFGPP----------------------------------NQQMSPSPMSHGHYSMHCLHS--------AGHSQPDGAYSSASSFS------RPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTV-VEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK--QGGAALEGSALANGRALS-AGSPP--------------------VPPGWNP------------------NSSSGKGSGSSAGSYVPS-YTSWYPSAH-QEAMQQPQLM-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q98875-1", "uniprot_id": "DLX1A_DANRE", "id": "Q98875-1", "name": "Homeobox protein Dlx1a", "aln": "-MTMSTIPES---LNSPVSGKSVFMEFGPP----------------------------------SQQMSPSSMTHGHYSMHCLHS--------SGHPQHDSAYSPAPSFP------RSLPYPYVNSVGSHSSSPYLSTVQTYPNNSALAQTRLEDPAPESEKNTV-VEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK--QGGGTIDTNALANGRGLS-TGSPS--------------------VAPVWN-------------------TTATVKTS--TPTSYIPS-YTSWYPTAH-QDTMQQPQLM-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98878-1", "uniprot_id": "DLX4B_DANRE", "id": "Q98878-1", "name": "Homeobox protein Dlx4b", "aln": "MMSMSFMSDT---LNSSDPSKSAFLEFGHG--------------------------------LASNQQHLSGFAHNIYPVHGLHS--------GGHLQHDAPYPSSAPHYS-----RPLGYAYPGPVSAAAPGAYMPYQPNN-HSGALAHTRAEN--TNHEKPAV-IENGEIRLNGKGKKIRKPRTIYSSVQLQALHQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMK--HGSSGPEGELLHTSSSS--PCSPG--------------------LSQLWE-------------------VSMANKVPPMHPSSYMNN-YGHWYPPHH-QDPVPRPQMM-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98879-1", "uniprot_id": "DLX4A_DANRE", "id": "Q98879-1", "name": "Homeobox protein Dlx4a", "aln": "-MTMTSLSES---LEASDPSKSAFLEFSHG--------------------------------YQSHQQHSPGVSHAHYPVHGLHQ--------GAHSQYDAAFSPGAASYS-----RPLAYHYS--TAHHHPGAYLPYQ----HNSAVGYSRVED--ADSEKQSS-IESGEIRLNGKGKKIRKPRTIYSSLQLQALNQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRSKYKKIMK--HGSSGPEGEHLQAASASGAPCSPG--------------------MPPLWD-------------------VSMPSKGAPIHSGGYMNS-FGHWYSGHH-QDPMARTQMM-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4AC19-1", "uniprot_id": "D4AC19_RAT", "id": "D4AC19-1", "name": "", "aln": "---MTSLPCP---LPGLGPSNVVFPDLAPA------------------------------------SSVVAAYQLGLSPGTAASP----------DLSFSQTYGHLLSYS--------YPGPATPGDSYLSSQQQSAAPSRPFHQPTEHPQELEA---ESEKLALSLEPSQP---SLTRKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK--QSSGELEEDFSGRPPSLS-PHSLT--------------------LPSIWD----------------------LPKAGTLPTSGYDNS-FGTWYQHHS-PDVLALPQRM-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70436-1", "uniprot_id": "DLX4_MOUSE", "id": "P70436-1", "name": "Homeobox protein DLX-4", "aln": "---MTSLPCP---LPDRGASNVVFPDLAPA------------------------------------LSVVAAYPLGLSPGTAASP----------DLSYSQSYGHPRSYS--------HPGPATPGDSYLPRQQQLVAPSQPFHRPAEHPQELEA---ESEKLALSLVPSQQQ--SLTRKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK--QSSGEPEEDFSGRPPSLS-PHSPA--------------------LPFIWG----------------------LPKADTLPSSGYDNSHFGAWYQHRS-PDVLALPQMM-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92988-1", "uniprot_id": "DLX4_HUMAN", "id": "Q92988-1", "name": "Homeobox protein DLX-4", "aln": "---MTSLPCP---LPGRDASKAVFPDLAPV------------------------------------PSVAAAYPLGLSPTTAASP----------NLSYSRPYGHLLSYP--------YTEPANPGDSYLSCQQP-AALSQPLCGPAEHPQELEA---DSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK--QNSGGQEGDFPGRTFSVS-PCSPP--------------------LPSLWD----------------------LPKAGTLPTSGYGNS-FGAWYQHHS-SDVLASPQMM-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20009-1", "uniprot_id": "DLL_DROME", "id": "P20009-1", "name": "Homeotic protein distal-less", "aln": "-MDAPDAPHTPKYMDGGNTAASVTPGINIP----------------------------------GKSAFVELQQHAAAGYGGIRS---------TYQHFGPQGGQDSGFP-------SPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPK------DDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGGNNGGGSNSGSPSHYLPPGHSPT--------------PSSTPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPPPQMGGYVPQYWYQPETNPSLVTVWPAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*:********: ** *::***.:*********:***.**************:*** **: * * . : ", "identical_positions": 48, "similar_positions": 14, "identity": "12.06%" }, { "cls_id": "homologset.agr.FB:FBgn0000163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2X6-1", "uniprot_id": "A0ABK0M2X6_RAT", "id": "A0ABK0M2X6-1", "name": "Partitioning defective 3 homolog B", "aln": "--------------------MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKIESPSGN-------PVDRQSPDAFDTE------VAAQLAAFKPIGGEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASPSGQSLKPVVLDSAQNLENRDVMNGEQTGLLMLHKTK-------------------------------------------------------------------------NELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCK-QEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPS---VVLHVLLPQNREQYEKSVIGQLNIFGNND-SASRTKAPPPTRGKAGLKAVNPTRANSPEGEESPSPQQ------------------SKSPR-----VPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEP--------------DCYALSLE---------------------------------------------------SSEQLTLEIPLNDSGSAGLGVSLKGNKSR-----------------ETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMS-MEGNIRGMIQLVILRRLER----------------PLEEISECGALSRPCFENCQEALSASRRNDSS----------------LLYPCGTYSPQDKRKDLLLPSDGWAENEVPPSPPPH-----------PSLEWGLEDFSHSSRVDSTGYFPDQH--------VNFRIVTPVGQPESINLKA-----SKSMDLVPDESKVQSLADRRSD---SPGKDFGPTLGLKKSSSLESLQTAVAEVRKND-LPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAEADG--------LSDKSSHSGHTALNCESAPQGNPELDDVENKAKNVKKTKEKEKKKGKGKMKVKEKKQKEE---HEDTERKMKRKGFGAMLRFGKKKDDKVGKTEQKGTQKS--GHPGEEELERMKEERERIGAKHQELREKQARGLVDYATVATGPVHDIDDDEMDPNYARVNHFREP--CTSAN---VFRSPSPPRAGTLGYPRDGRPLSP--DHLEGLYAKVNKPYH-----------PPALADSGRPMAGTTDRIQKLRKEYYQARRE------------GFLLYE----------------------------------------------DEEGVTRPSDYDLHWVSGKGPDGSAHNLRFEGMERQYASLPRGGSADPVDYLTASPRGRYNERELPYYPGPHP-VHSPRGSY-------------PRPPDLRVTDLRYPQYYPPPPAHQHKGPFRQDVPPSPPQHQRVP-VYQEMG---------------RAGPR-GGSPDQYP----YRNQDPRQKNPMTAAV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CSB4-1", "uniprot_id": "PAR3L_MOUSE", "id": "Q9CSB4-1", "name": "Partitioning defective 3 homolog B", "aln": "--------------------MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKTESPGGN-------PADRQSPDAFETE------VAAQLAAFKPVGGEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASLSGQSLKPVVLDSTQNVENKEAMNGEQAGLLSLHRPK-------------------------------------------------------------------------DELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCK-QEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPS---VILHVLLPQNREQYEKSVIGPLNIFGNND-GASRTKAAPPARGKPGLKAVHLTRASSPEGEEPASPQQ------------------SKSPR-----VPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEP--------------DCYALSLE---------------------------------------------------SSEQLTLEIPLNDSGSAGLGVSLKGNKSR-----------------ETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMS-MEGNIRGMIQLVILRRPER----------------PLEELSECGALSRPGFENCQEALSTSRRNDSS----------------ILYPFGTYSPQDKRKDLLLPSDGWAENEVPPSPPPH-----------PALEWGLEDFSHSSGVDSTGYFPDQH--------VNFRTVTPVRQPELINLKA-----SKSMDLVPDEGKVQSLADRRSD---SPGKDFGPTLGLKKSSSLESLQTAVAEVRKND-LPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEADADG--------LSDKSSRSGHTALNCESAPQGNPELDNVENKAKNIKKTKEKEKKKGKGKLKVKEKKLKEE---HEDAERKMKRKGFGAMLRFGKKKDDKVGKAEQKGAQKS--GHPEEEELERMKEERERIGAKHQELREKQARGLVDYATAVTGPVHDMDDDEMDPNYARVNHFREP--CASAN---VFRSPSPLRAGPLAYPRDGRPLSP--DHLEGLYAKVNKPYH-----------PPALADSGRPMAGTTDRIQKLRKEYYQARRE------------GFLLYE----------------------------------------------DENTRARPSDHDLRWVSGKGPDGSTHNLRFEGMERQYASLPRGGSADPVDYLTASPRGRYNDRELPYYPGPHP-VHAPRGSY-------------PRPPDLRATDLRYPQYYPPPPAHQHKGPFRQDVPPSPPQHQRVP-VYQEMG---------------RAGPR-GSSPDQYP----YRNQDPRQKNPMTAAV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEW8-1", "uniprot_id": "PAR3L_HUMAN", "id": "Q8TEW8-1", "name": "Partitioning defective 3 homolog B", "aln": "--------------------MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFEEQEPLHKIESPSGN-------PADRQSPDAFETE------VAAQLAAFKPIGGEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKLVVPDSTQNLEDREVLNGVQTELLTSPRTK-------------------------------------------------------------------------DTLSDMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFIRGIEDNSRSK-REGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPS---VLLHVLPPQNREQYEKSVIGSLNIFGNND-GVLKTKVPPPVHGKSGLKTANLTGTDSPETDASASLQQ------------------NKSPR-----VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEGHFLPRELKGEP--------------DCCALSLE---------------------------------------------------TSEQLTFEIPLNDSGSAGLGVSLKGNKSR-----------------ETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMS-MEGNIRGMIQLVILRRPER----------------PMEDPAECGAFSKPCFENCQNAVTTSRRNDNS----------------ILHPLGTCSPQDKQKGLLLPNDGWAESEVPPSPTPH-----------SALGLGLEDYSHSSGVDSAVYFPDQH--------INFRSVTPARQPESINLKA-----SKSMDLVPDESKVHSLAGQKSE---SPSKDFGPTLGLKKSSSLESLQTAVAEVRKND-LPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIEADG--------LSDKSSHSGQGALNCESAPQGNSELEDMENKARKVKKTKEKEKKKEKGKLKVKEKKRKEE---NEDPERKIKKKGFGAMLRFGKKKEDKGGKAEQKGTLKH--GGLREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYDMDDDEMDPNYARVNHFREP--CTSAN---VFRSPSPPRAGPFGYPRDGHPLSPERDHLEGLYAKVNKPYH-----------PLVPADSGRPTGGSTDRIQKLRKEYYQARRE------------GFPLYE----------------------------------------------DDEGRARPSEYDLLWVPGRGPDGNAHNLRFEGMERQYASLPRGGPADPVDYLPAAPRGLYKERELPYYPGAHP-MHPPKGSY-------------PRPTELRVADLRYPQHYPPPPAPQHKGPFRQDVPPSPPQHQRMP-AYQETG---------------RPGPR-GGSPDQYP----YRTQDSRQKNPMTAAV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YYR6-1", "uniprot_id": "A0A8M6YYR6_DANRE", "id": "A0A8M6YYR6-1", "name": "", "aln": "--------------------MKVTVIFGETRVVVPCKDS-WMVRDLIDQATQRYKKIVEQDGEFLVRTLHVEYVDGGILDPDDMLSDLVEDKEKLTAVFEKLELQQRALVSPGG-----SFASGRSSPDHSEPE------LNILHPYL---SSEIEVTPSALKSTTPLSVRSSSDPALAPPLDAISLDSEDSSRPQSTGVAPPVTVKGG--AMDKLKVDNLISRNGQ-------------------------------------------------------------------------DTLRSLTRTVEISGDHGPLGIKVIPYCSSLSGRTLGLNIRAIEKNSRSE-REKIFEEDECIVQINDAELIDKSFAQSQEVFRQAMSSSSTSTVHLEVLPVANKLRYEKSLIGQLFNSTETN-PAVPKIKSPFLVRKLTPSNTATPSPEPAASQTPPIKEEELQRARHTPVELNH---QSSTPSPPVSTSPTLRDHSESPALASVVHMVTKKAGKRMRIDLKKGTEGLGFTVVTRDSSLHGPGPIMVKSILPRGAAVKDGRLKSGDRILEVNGVDITGRTQEELVAMLRSTKLGETVSLIVGRQE-EFLPRELKGEV--------------SGPLVSED---------------------------------------------------GREQLMFEVPLNDSGSAGLGVSLKGNKSR-----------------ETGEDLGIFIKSIIHGGAANKDGRLRVNDQLIAVNSESLVGRSNHDAMETLRHSMS-TEGNLRGTIQLVVLRSLERS---------------PAQENYEASQSANRNDSPVLRRHHHHPNSNTTNN---------SVPQSTVNESAPAPYRPHGGRPELLEVDYGEDDFPPPPSDL-----------DLLETNPPHKHQPNRPEMEPFSQVSHP-------TNQQYPQRQKAPEYSTNKT-----SKSMDLVADESNMASIQGQRPEPISSNGTALGPRLGLRKSSSLESLQTAMEEVSKDE-VPFHRPRAHMVRGRGCNMSFRYAIDKSYEGPSEAEDDD---------SEEDS--GRDTPASSSSRQ---ELDNDRKVKK--KKTKKKKEKKTK--------KKDE----AEDPDKKTKKKGFG-LLSMETSPDLRSVQKNMFGRKNKEDKTKSKAKQMVAVSEEEVDKSEPELFLSKSERNSPAPERVIF---PDVEDDDLDPNYARINNFRNP--PASSQSPLPPGAPTNNYAQPAVPAPSREPPNE--DALEGLYAKVNKQRT-----------APP-KTESN-----EERLQQIRNQLQQIR--------------PAPSYE----------------------------------------------DLTARRR-PEYDPSR--IRGPD-SRTAPRYNDADRLYTSVPRKKPVD--EYPNQN---WSNQRDPVLYPNP---IYDNPPRS-------------PRLPVPKPTETP----GAHYPSSPAKQMMRQDVPPSSNPGAREPPRYEALN---------------QGNYR-TASPDRYSPYTDEQYQDPRRKNPMIGAV------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UUX7-1", "uniprot_id": "A0A8N7UUX7_DANRE", "id": "A0A8N7UUX7-1", "name": "", "aln": "--------------------MKVTVTFGRTGVVVPCKEG-WTVRDLILQATQRYRKLLEQEGDFLVRTHHVEYCDGGILDPDDVLTDLVEDKDKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSE------LACFQPIK---GGEIEVTSSALKSSTPLLVRSSSDSALG-----ASQMEDMNSRAMGIHVQTDMDFT-----------AELTGNKSG-------------------------------------------------------------------------PLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSK-REGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSS---IVRLEVVPVFNKERFEKSVISHLFNPETPD-ASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLE--SRSLGSPLPIN----LSPTPRGKSAENSLLKNSLGP----SPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQ--------------ARLLLSEE---------------------------------------------------GKEQLMFEVPLNDSGSAGLGVSLKGNKSR-----------------ETGEDLGIFIKSIIHGGAAFKDGRLRINDQLIAVNGEPLLGKSNHEAMETLRRSMS-MEGNLRGMIQLVVLRSVLP----------------PNQEFQEARRILNRSFDSCVGQAAHLSQSDAG-----------VQPPMVMNSIYERCAVSNGGYNHTEEGD--DEGFDANPHRQ-----------NSLQFQQSLLSSGLRSADASLTDGGQ----------------QVHAEQNHVKS-----LKSVDLVSG------------------GVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDE--------GSEQSS--GRDTPASGSSRQGAGDNEENKKDKK--KKAKSKKKEKMKSKGKEKEKKKSEEI--GDELDKKTKKKGFG-LLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGR-----DRFSP---PDLEDDDLDPNYARINNFKER--GSPSQPLYGNRSPSPQRPLAAVSH-SREPSTE--DPLDGLYAKVNKQRS-----------PPPPAADSS-----MDRIQQLRREYLQARREG-----------TAPAYD----------------------------------------------ELEARRRGAEHDPHRMPMRNPD-PRLAPRYEDVERQYASLPRRAPADPNEYPVQQ---WSAHREPAQYPNPQSGYHPGYPPP-------------PREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGP-RFDTMS---------------RGGYR-NTSPERYA-YGDQRHSDPRQKSPMTAAV------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z340-1", "uniprot_id": "PARD3_RAT", "id": "Q9Z340-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSAS-------STGTQSPEIFGSELGTNN-VSAFRPYQT--TSEIEVTPSVLRANMPLHVRRSSDPALTGLS-TSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTTGSPKTCDRKKD--ENYRSLPRDPSSWSN--QFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSA-RGGRTLGLLVKRLEKGGKAE-QENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARV---IWFHVVPAANKEQYEQLSQREMNNYS----PGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHA-------STKPP-----TAPALAPPNVLSTSVGSVYNTKRVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQSPKETKAEDEDIVLTPDG---------------------------------------------------TREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMS-TEGNKRGMIQLIVARRISRCNELRSPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALS-RIMGESGKCQLSPTVNMPHDDTVMIEDDRLPVLPPHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSNASQLDFVKTRK-----SKSMDLGIADETKLNTVDDQRA--GSPNRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPMVDDDDE-GMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKAEKKKDKAGKDKKKDREKEKDKL------KAKKGMLKGLGDMFRFGKHR--KDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQAR---------------------ERDYAEIQDFHR---TFGCDDELLYGGMSSYDG--CLALNARPQSPREGHLMDTLYAQVKKPRSS----------KPG--DSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQSWS----------------------------------------------SSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSVSQDSWEQNYAPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQLKKQPPADG-----------------VRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NH2-1", "uniprot_id": "PARD3_MOUSE", "id": "Q99NH2-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSAS-------FTGTQSPEIFGSELGTNN-VSAFQPYQA--TSEIEVTPSVLRANMPLHVRRSSDPALTGLS-TSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD--ENYRSLPRDPSSWSN--QFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSA-RGGRTLGLLVKRLEKGGKAE-QENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARV---IWFHVVPAANKEQYEQLSQREKNNYS----PGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHA-------STKPP-----AAPALAPPSVLSTNVGSVYNTKKVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQTPKETKAEDEDVVLTPDG---------------------------------------------------TREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMS-TEGNKRGMIQLIVARRISRCNELRSPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALS-RIMG---KCQLSPTVNMPHDDTVMIEDDRLPVLPPHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRK-----SKSMDL-VADETKLNTVDDQRA--GSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPMVDDDDE-GMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKTERKKDKAGKDKKKDREKEKDKL------KAKKGMLKGLGDMFRFGKHR--KDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQAR---------------------ERDYAEIQDFHR---TFGCDDELLYGGMSSYEG--CLALNARPQSPREGHLMDTLYAQVKKPRSS----------KPG--DSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQSWS----------------------------------------------SSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSISQDSWEQNYAPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQLKKQPPADG-----------------VRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEW0-1", "uniprot_id": "PARD3_HUMAN", "id": "Q8TEW0-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSAS-------STGTQSPEIFGSELGTNN-VSAFQPYQA--TSEIEVTPSVLRANMPLHVRRSSDPALIGLS-TSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD--ENYRSLPRDTSNWSN--QFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSA-RGGRTLGLLVKRLEKGGKAE-HENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPI---IWFHVVPAANKEQYEQLSQSEKNNYY----SSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHP-------SGKPP-----SAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDG---------------------------------------------------TREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMS-TEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALS-RIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRK-----SKSMDLGIADETKLNTVDDQKA--GSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDE-GMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKM------KAKKGMLKGLGDMFRFGKHR--KDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQAR---------------------ERDYAEIQDFHR---TFGCDDELMYGGVSSYEG--SMALNARPQSPREGHMMDALYAQVKKPRNS----------KPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQPWP----------------------------------------------NARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9K4-1", "uniprot_id": "A0AB13A9K4_DANRE", "id": "A0AB13A9K4-1", "name": "", "aln": "--------------------MKVTVCFGRTRVVVPCGDGNIKVQSLVQQAAMRYRRAIAKGEEYWVQVYRLEHGDGGILDLDDVLCDVADDKDRLVAVFDEQEPHVGGDGTSAS-------STGTQSPELYCGEPSTSTPLSAFQPYLP--HSEIEVTTSTLRTNMPLHVRRSSDPALLNLTAMSFSEPGSQPEEPSRKNPTRWSTTAGFLKPRFATGTNSLERKGRGVDTYRSLPRDAGQWSNQKEFQREKARSSLSANHPMVDRWLERQEQD----EEENGRIEPVGRADTCLEHMGVRSLDDIVKLVEVSNDGGPLGIHVVPFSG-RDRRTLGLLVKRLERGGKAD-VQGLFQENDCIIRINNGDLRNVRFEQAQNMFRQAMRSPV---ILFHVVPTTMRSQYEQISHNEHNPRANIDLSGRFSPDSLTNDLDSAAHRLAQHRP-----QQPNNHLDTGSPVHHLVGS-------SGKPP-----TGHTSSPQRGLSPAPTTGF-TKKVGRRLGIQLKKGPEGLGFSITSRDVPLGGSAPIYVKNILPRGAAIQDGRLKAGDRLLEVNGVDLNGRGQEEVVSLLRATPMGGTVTLVVLRQEETFIPREMNAEP-AIQNTREWKVEEEELVLTPDG---------------------------------------------------TREFLTLEVPLNDSGSAGLGVSVKGNRSK-----------------ESHADLGIFVKSIINGGAACKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRKSMS-TEGNKRGMIQLIVARRINKRLEGESRGSPRGLERTLSPSPDDHERRISHSLY-GIEGLDDNLRPQASTNNRKMN---HYQLSPTVNMPQDDTVIIEDDRPHVLPIQLSDQSSSSSHDDMGFAVETP--PPPPWEPELPDSSSSANAEG--QFQREGFGRQSMSEKRTKQYGDAGQLDIIKTRK-----SKSMDL------------------GSSTRDVGPSLGLKKSSSLESLQTAVAEVTLNGDMPFHRPRPRIIRGRGCNESFRAAIDKSYDRPAANEDEEECMDTLEEDTEGSSRSGRDSVSTVADLTPLPVTEQQLINGNQPE-NDKKKEKGGKDKKK---PEKEKG------KTKKGMLKGLGEMFRFGKYR--KDERLDG-AKWKAEETHASEEETRRMKQEQERIQAKTREIRQRQAR---------------------ERDYAEIQDFSRSTLTSLPPEEPPYAGIGSLEHGGYHRIHTPPDSP---------YTQKQNGRNG----------HPS--TSDRLTPSNHDRIQRLRQEFQQVRQEETEPDDRHRSYSMEQPWS----------------------------------------------NCSSQSSSGRHSVSVEVQLQR--QEARDAFTHAQRQYSSLPRHPRKTPTPASESEWERTGPSVDAFQAAKDSGRYSSYQGPRSVPRTVPRHGCRNGFSAAPGSSSSSVGSGYNARVLLEAQELLRQEQRRREQEMKGRGPSIR----------VDYECQDSKGPQRQDVPPSPSQVVRLSRIHTPEKTRPFLS--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHR3-1", "uniprot_id": "Q0KHR3_DROME", "id": "Q0KHR3-1", "name": "", "aln": "MFDVPPKCPALANKLGGLFGWRHTYKVAAKQEGIPHGQLHKSYSLTLPKRPPSPSTYSCVKPDSWVTVTHLQTQSG-ILDPDDCVRDVADDREQILAHFDDPGPDPGVPQGGGDGASG-SSSVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNLLASLKAEGSNKRWSAAAPHYAGGDSPERLFLDKAGGQLSPQWEEDDDPS-------------------------------------------------HQLKEQLLHQQQPHAANGGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQNGAYSSKSLPRESKRKEPLGQAYESIREKDGEMLLIINEYGSPLGLTALPDKEHGGGLLVQHVEPGSRAE-RGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSLPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKILRS--------------ASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNS----------SSNASDNSGATVIYLSPEKREQRCNGGGGGGSAGNEMNRWSN---------PVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAALRNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPARPHDGQHCNTSSANPSQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAALDARETGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIEQRETQQQLAAAEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMSDEPRGHQALRAPRGRGREDSLRAAVVSEPDASKPRKTWLLEDGDHEG--GFASQRNGPFQSSLNDGKHGCKSSRAKKPSILRGIGHMFRFGKNRKDGVVPVDNYAVNISPPTSVVSTATSPQLQQQQQQQLQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPNGVGSNGIHQNDIFNHRYQHYANYEDLHQQHQQHQISGGDSTTSISETLSESTLECMRQQVIRQRIKVEAESRRHQHYHSQRSARSQDVSMHSTSSGSQPGSLAQPQAQSNGVRPMSSYYEYETVQQQ---RVGSIKHSHSSSATSSSSSPINVPHWKAAAMNGYSPASLNSSARSRGPFVTQVTIREQSSGGIPAHLLQQHQQQQLQQQQPTYQTVQKMSGPSQYGSAAGSQPHASKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. . :* : : : ::: .* *** ** : *:.:*:::: * ::. .. . **: .: . * ** ***. :.: . * : : : . . : : ... . : : . : . :. : : : : : : . : . ..: .::: * ****.:****::.:** . * ** :*.***:***::****:.***::**:* : *: * ::*::**. :. ::: **: : * . * * :.:*::*: .******:**: . : *****:*.:*:**** :*****:****::**. .* *: * :******::* *: * * *:: * : : . : .. : ..* * : .. .. :: * : . . .* : ... . : : .. . . : . . . . . : : . .* : : * : : . . : : .: . :: *: .: * : : . .* : . :. : : . : . : . . ", "identical_positions": 117, "similar_positions": 202, "identity": "7.27%" }, { "cls_id": "homologset.agr.FB:FBgn0000173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61089-1", "uniprot_id": "UBE2N_MOUSE", "id": "P61089-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61088-1", "uniprot_id": "UBE2N_HUMAN", "id": "P61088-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQX9-1", "uniprot_id": "UBE2N_RAT", "id": "Q9EQX9-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAG-PQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKSNEAQAIETARAWTRLYAMNNI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JXB2-1", "uniprot_id": "UE2NL_HUMAN", "id": "Q5JXB2-1", "name": "Putative ubiquitin-conjugating enzyme E2 N-like", "aln": "MAELPHRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGESKDSPFEGGTFKRELLLAEEYPMAAPKVRFMTKIYHPNVDKLERISLDILKDKWSPALQIRTVLLSIQALLNAPNPDDPLANDVVEQWKTNEAQAIETARAWTRLYAMNSI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35128-1", "uniprot_id": "UBE2N_DROME", "id": "P35128-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTG-PNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52490-1", "uniprot_id": "UBC13_YEAST", "id": "P52490-1", "name": "Ubiquitin-conjugating enzyme E2 13", "aln": "MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEG-PEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: **:******::*: :*****.* *.:.* ***:* : * .::**:*.* *: ** *.::*** ******:*******:*:* **.**:** :*********:******** :***:*******.* * ** * .** **: ** :. ", "identical_positions": 93, "similar_positions": 35, "identity": "60.39%" }, { "cls_id": "homologset.agr.FB:FBgn0000179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0C0-1", "uniprot_id": "F1M0C0_RAT", "id": "F1M0C0-1", "name": "", "aln": "-------------MREP-ALAASAMAYHPFH--APRPADFPMSAFLAA-----------------------------------------------------------------------------------------------------------------------------------------------AQPSFFP------------ALALPPGALAKPLPDPGLAGAAAAAAAAA--------AAAEAGLHVSALGPHP-------------------------------------------PAAHLRSLKSLEPEDE-VEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF--------------------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLPTLRLYEEHCKPERDGAESDASSCDPPPAREPPPSP-SAAPSPLR------LHRARAEEKPCAADSDPEPERSGEERAAAPLGRSSSRD--------ASPARLTEPERSRERRSPERGSKEPTEGG-GDGPFSLRSLEKERAEARR---KDEGRKDVG----EGKEPSLAPLVVQTDSA-SPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFAMGPGAFSAMGMG---HLLASVAGGGGNSGGAAPGTAAGLDAGGLGPAASAA----STATPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGS--ARPRLR-FSPYQIPVTIPPSTSLLTTGLAA----ESSK--GGNSREPSPLPELALRKVGGPSRGALSPSGSA----------KEAASELQSIQRLVSGLESQRALSPGRESPK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60707-1", "uniprot_id": "TBX2_MOUSE", "id": "Q60707-1", "name": "T-box transcription factor TBX2", "aln": "-------------MREP-ALAASAMAYHPFH--APRPADFPMSAFLAA-----------------------------------------------------------------------------------------------------------------------------------------------AQPSFFP------------ALALPPGALGKPLPDPGLAGAAAAAAAAA--------AAAEAGLHVSALGPHP-------------------------------------------PAAHLRSLKSLEPEDE-VEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF--------------------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLPTLRLYEEHCKPERDGAESDASSCDPPPAREPPPSP-SAAPSPLR------LHRARAEEKPGAADSDPEPERTGEERSAAPLGRSPSRD--------ASPARLTEPERSRERRSPERCSKEPTEGG-GDGPFSLRSLEKERPEARR---KDEGRKDVG----EGKEPSLAPLVVQTDSA-SPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFAMGPGAFSAMGMG---HLLASVAGGSGSSGGAGPGTAAGLDAGGLGPAASAA----STAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGS--ARPRLR-FSPYQIPVTIPPSTSLLTTGLAA----EGSK--GGNSREPSPLPELALRKVGGPSRGALSPSGSA----------KEAASELQSIQRLVSGLESQRALSPGRESPK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13207-1", "uniprot_id": "TBX2_HUMAN", "id": "Q13207-1", "name": "T-box transcription factor TBX2", "aln": "-------------MREP-ALAASAMAYHPFH--APRPADFPMSAFLAA-----------------------------------------------------------------------------------------------------------------------------------------------AQPSFFP------------ALALPPGALAKPLPDPGLAGAAAAAAAAA--------AAAEAGLHVSALGPHP-------------------------------------------PAAHLRSLKSLEPEDE-VEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF--------------------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSP-GAAPSPLR------LHRARAEEKSCAADSDPEPERLSEERAGAPLGRSPAPDS-------ASPTRLTEPERARERRSPERG-KEPAESG-GDGPFGLRSLEKERAEARR---KDEGRKEAA----EGKEQGLAPLVVQTDSA-SPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFTMGPGAFSAMGMG---HLLASVAGG-GNGGGGGPGTAAGLDAGGLGPAASAA----STAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGS--ARPRLR-FSPYQIPVTIPPSTSLLTTGLAS----EGSKAAGGNSREPSPLPELALRKVGAPSRGALSPSGSA----------KEAANELQSIQRLVSGLESQRALSPGRESPK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZTU9-1", "uniprot_id": "TBX2_DANRE", "id": "Q7ZTU9-1", "name": "T-box transcription factor TBX2b", "aln": "-------------MRDP-VFTGTAMAYHPFH--AHRPTDFPMSAFLAA-----------------------------------------------------------------------------------------------------------------------------------------------AQPSFFP------------ALTLPPGALTKPIPDHTLAG------------------AAEAGLHP-ALSHHH-------------------------------------------QAAHLRSLKSLEPEEE-VEDDPKVTLEAKDLWDQFHKLGTEMVITKSGRRMFPPFKVRINGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF--------------------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLPSLRMYEDQCKVDRDGADSDASSSEPTTGRDAGHSP-GPVSSPLR------FNRGSRDDKT-CTDSEHEMDHQNDRCGGS---SSPAPEP-------SSPFRSRSEDWGREKPIAEKKDDYPDSRKTSDSIFSIRNLEKDKLESRSRKDTDSSKKDTENSGISGSKDSFSPLMVQTESP-SHFGAGHLQSLALSG-LHSQQFFNPLNTGQPLLFHPGQFAMAPGAFSAMGMG---HLLASVSGA------------GGLENGSLS-AQGTG----STPSPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPASS------STASSLSRNPFLSSS-TRPRLR-FNPYQLPVSIPQSTNLLTTGLPSGL-NPSSESSKCGSREASPVPD---HKSGA-SQRNGSPKTTM----------KESINELQNIQRLVSGLESQRETSSPRDSPK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BCU2-1", "uniprot_id": "A0A8M2BCU2_DANRE", "id": "A0A8M2BCU2-1", "name": "", "aln": "-------------MRDP-VFTANAMAYHPFH--AHRPADFPMSAFLAA-----------------------------------------------------------------------------------------------------------------------------------------------AQPSFFP------------ALTLPPG-LSKPLADHALSG------------------AAEAGLHA-ALGHHH-------------------------------------------QAAHLRSFKGLEPEED-VEDDPKVTLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVNGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF--------------------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKSLNFRKQLAMPSMRMYDDQCKVDRDGGDSDDSSCEQTTGRDSVHSPTGPATSPLK------FTR-SREDKN-FNESDNELDQHDDGMIRV---SSPEQRP-------QSPFSPRCEDRVKDRLNLEKKGDYSDSRKENDSAFSIRHLDKDKLDARNVKDQDSSKKEADSVGMSTVKDGFSPLMVQTENP-SHFSASHLQSLALSG-LHNQHFFNPLSSGQSLLFHPGQFAMTPSAFSTMGMG---HLLASMSGA------------SGLENGSLS-SQST-----SSPNPFPFHLSQHMLASQGISMPTFGGLLPYPYTYMAAAAAAASALPAG-------SAASSLSRNPFLNN--TRPRLR-FSPYQIPMSFSQSSGLLTTGIPSTM-SAESESSKSGSRESSPMSEHHSHKTGN-GQNTGSPKSSG----------KDSINELQNIQRLVSGLEKHRDASPRSVSPK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TST9-1", "uniprot_id": "TBX3_RAT", "id": "Q7TST9-1", "name": "T-box transcription factor TBX3", "aln": "---------MSLSMRDP-VIPGTSMAYHPFL--PHRAPDFAMSAVLG------------------------------------------------------------------------------------------------------------------------------------------------HQPPFFP------------ALTLPPNGAAALSLPGALAKPIMDQLVG----------AAETGIPFSSLGPQ----------------------------------------------AHLRPLKTMEPEED-VEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSN------LKDLCPSEAESDAEAESKEEHGPEACDTAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRH-SPATISSSTRVPGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDAT-AHLTQGPLPGLGFAPGLAGQQFFN----GHPLFLHPGQFAMG-GAFSSMAAG-MGPLLATVSGASTG--------VSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSA-----------AASSSVHRHPFLNLNSMRPRLR-YSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKSAVLAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRS-CSGSP-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70324-1", "uniprot_id": "TBX3_MOUSE", "id": "P70324-1", "name": "T-box transcription factor TBX3", "aln": "---------MSLSMRDP-VIPGTSMAYHPFL--PHRAPDFAMSAVLG------------------------------------------------------------------------------------------------------------------------------------------------HQPPFFP------------ALTLPPNGAAALSLPGALAKPIMDQLVG----------AAETGIPFSSLGPQ----------------------------------------------AHLRPLKTMEPEED-VEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLQSMRVFEERHKKET--SDESSSEQAAFNCFAQASSPAVSIVGTSN------LKDLCPSEAESDAEAESKEEHGPEACDAAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRH-SPATISSSTRVPGADERRSPGREGPVATKVDEARAIPAKDAFAPLSVQTDAT-AHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHPGQFAMG-GAFSSMAAG-MGPLLATVSGASTG--------VSGLESTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASTA-----------AASSSVHRHPFLNLNSMRPRLR-YSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKAAALAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRS-CSGSP-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15119-1", "uniprot_id": "TBX3_HUMAN", "id": "O15119-1", "name": "T-box transcription factor TBX3", "aln": "---------MSLSMRDP-VIPGTSMAYHPFL--PHRAPDFAMSAVLG------------------------------------------------------------------------------------------------------------------------------------------------HQPPFFP------------ALTLPPNGAAALSLPGALAKPIMDQLVG----------AAETGIPFSSLGPQ----------------------------------------------AHLRPLKTMEPEEE-VEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK----RKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTSN------LKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE--RPRDSGRLDKASPDSRH-SPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHPSQFAMG-GAFSSMAAAGMGPLLATVSGASTG--------VSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSA-----------AASSSVHRHPFLNLNTMRPRLR-YSPYSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRS-RSASP-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24432-1", "uniprot_id": "OMB_DROME", "id": "Q24432-1", "name": "Optomotor-blind protein", "aln": "MRYDVQELLFHQSAEDPFARFANGMAYHPFLQLTQRPTDFSVSSLLTAGSNNNNSGNTNSGNNNSNSNNNTNSNTNNTNNLVAVSPTGGGAQLSPQSNHSSSNTTTTSNTNNSSSNNNNNNSTHNNNNNHTNNNNNNNNNTSQKQGHHLSTTEEPPSPAGTPPPTIVGLPPIPPPNNNSSSSSSNNSASAAAHPSHHPTAAHHSPSTGAAAPPAGATGLPPPTPPHHLQQQQQQQQHPAPPPPPYFPAAALAALAGSPAGPHPGLYPGGGLRFPPHHPGAHPHAHHLGSAYTTAEDVVLASAVAHQLHPAMRPLRALQPEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVS-----------------TTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREK------KQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGPPQSPLLPLSHSLQQMHAHQHSAALAAWFNHLAG---AGAGASEHAAAAAANASAEDALRRRLQADADVERDGSDSSCSESVGGSTGGAFRPTSTGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSPHLLPYLYPHGLYPP---PHLGLLHN---PAAAAAMSPAGLN--PGLLFNAQLA-----------LAAQHPALFGHAYAAAG---HTPVSPLQGLKSHRFSPYSLPG-SLGSAFDAVTPGSNANRSGDPPGGGGG-----GLGGGVVENGPRSLSSSPRPRPASHSPPTRPISMSPTTPPSLMKQPRGGGAGAGVAQSQHSPSELKSMEKMVNGLEVQHNGSAAAAAAALQLAEEAAQHHHHTQAHHQQQQHQSHHQQQHHQQPAQPHPHHQTHLHSHHGATTGGTDQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* . ...****** . *..**.:*:.* :*...* * . . * ** :.: . . : . :*.:: ::**:: * ***** **.*:**::*** ***********:*** :*.* .*** *******:**:**** ******************************:****** * *:**************** **************:*****************:* **:*********:******************** *:*** : :: : * :. ... . * . . . : : :. : . . . . . . . .. .: * . . . . : * : :: : ::* . .*:*. . ** . . .. . :. : .: :. . *..* ::. .:. .:*. : . * :. .. .. : . * *** ..* *:... : . . . : . . :. *: * : : . * ", "identical_positions": 210, "similar_positions": 149, "identity": "20.47%" }, { "cls_id": "homologset.agr.FB:FBgn0000180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55087-1", "uniprot_id": "AQP4_HUMAN", "id": "P55087-1", "name": "Aquaporin-4", "aln": "---------------------MSDRPTARRWGKCG---------PLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGG---TEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHG-LLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWEN-HWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55064-1", "uniprot_id": "AQP5_HUMAN", "id": "P55064-1", "name": "Aquaporin-5", "aln": "------------------------------------------------------MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWP------SALPT-ILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQA-MVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPN-------SLSLSERVAIIKGTYEPDEDWEEQRE-------------------ERKKTMELTTR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29972-1", "uniprot_id": "AQP1_HUMAN", "id": "P29972-1", "name": "Aquaporin-1", "aln": "------------------------------------------------------MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQG-LGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSN-HWIFWVGPFIGGALAVLIYDFILAPR-------SSDLTDRVKVWTSG--QVEEYDLDAD-------------------DINSRVEMKPK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23645-1", "uniprot_id": "BIB_DROME", "id": "P23645-1", "name": "Neurogenic protein big brain", "aln": "MADESLHTVPLEHNIDYHIVTLFERLEAMRKDSHGGGHGVNNRLSSTLQAPKRSMQAEIRTLEFWRSIISECLASFMYVFIVCGAAAGVGVG----ASVSSVLLATALASGLAMATLTQCFLHISGAHINPAVTLALCVVRSISPIRAAMYITAQCGGGIAGAALLYGVTVPGYQGNLQAAISHSAALAAWERFGVEFILTFLVVLCYFVSTDP-MKKFMGNSAASIGCAYSACCFVSMPY----LNPARSLGPSFVLNKWDS-HWVYWFGPLVGGMASGLVYEYIFNSRNRNLRHNKGSIDNDSSSIHSEDELNYDMDMEKPNKYQQSQGTYPRGQSNGNGGGQAAGNGQHQAANMGQMPGVVANAGQGNYCQNLYTAPPLSSKYDQQQEPLYGGTRSLYCRSPTLTRSNLNRSQSVYAKSNTAINRDIVPRPGPLVPAQSLYPMRTQQQQQQQQQQQQQVAPAPQSSHLQNQNVQNQMQQRSESIYGMRGSMRGQQQPIQQQQQQQQQQQLQQQQPNMGVQQQQMQPPPQMMSDPQQQPQGFQPVYGTRTNPTPMDGNHKYDRRDPQQMYGVTGPRNRGQSAQSDDSSYGSYHGSAVTPPARHPSVEPSPPPPPMLMYAPPPQPNAAHPQPIRTQSERKVSAPVVVSQPAACAVTYTTSQGSAVTAQQQQQQQQQQQQQQQQQQQQMMMQQQQQHYGMLPLRPN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * ::: :* ** ::*:: *:: . : :*. **::.*:.*.. :**.*:***:*:.: .** :: :*: ** *.* .:.:* :: ..* . . : :*:* *: :.: :.: * . *. . :** : : :..: : :*****:*.:.: .:. **::*.**::*. : :* ::: . . : . . : : : : . ", "identical_positions": 47, "similar_positions": 97, "identity": "6.66%" }, { "cls_id": "homologset.agr.FB:FBgn0000181", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96K17-1", "uniprot_id": "BT3L4_HUMAN", "id": "Q96K17-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3I4-1", "uniprot_id": "D4A3I4_RAT", "id": "D4A3I4-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQH7-1", "uniprot_id": "BT3L4_MOUSE", "id": "Q9CQH7-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PC91-1", "uniprot_id": "BT3L4_DANRE", "id": "Q6PC91-1", "name": "Transcription factor BTF3 homolog 4", "aln": "-------------------------------------------------MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLVVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAETKQLTEMLPGILSQLGADSLTSLRKLAEQFPRQVLDNKAPKAEDIDEEDDDVPDLVENFDEASKNEAN-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q64152-1", "uniprot_id": "BTF3_MOUSE", "id": "Q64152-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPTQADSRGRGRARGGWPGAEATPSLP--LGGSRGRESQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDD-DDEVPDLVENFDEASKNEAN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R5M7-1", "uniprot_id": "M0R5M7_RAT", "id": "M0R5M7-1", "name": "Transcription factor BTF3", "aln": "--------------------------------------------MKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNSISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLAAGEEE-EDEVPDLVENFDEASKNEAN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20290-1", "uniprot_id": "BTF3_HUMAN", "id": "P20290-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDD-DDEVPDLVENFDEASKNEAN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KM15-1", "uniprot_id": "Q7KM15_DROME", "id": "Q7KM15-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNAEKLKKLQAQVRIGGKGTPRRKKKIVHSTPATDDKKLQSSLKKLSVNTIPGIEEVNIIKNDGTVIHFNNPKAQASLPTNTFAITGHGENKTITEMVPGILTQLGPQDINQLKKLATEIASKSGAGGAAGSSAADAGDDDVPDLVENFEEVAIADTKEEKSGEVAASA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40314-1", "uniprot_id": "NACB2_YEAST", "id": "P40314-1", "name": "Nascent polypeptide-associated complex subunit beta-2", "aln": "--------------------------------------------MPVDQEKLAKLHKLSAANKVGGTRRKINKKGNLYNNNDKDNTKLQAELHKLHPMTIENVAEANFFKKNGKVLHFNSAVVQIAPQCNLTMIHGQPKENTLNGLYPSVASQLGSQELEYLTGLAHNLENE----QTVLDQLGDRCSETKQQVMNS---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02642-1", "uniprot_id": "NACB1_YEAST", "id": "Q02642-1", "name": "Nascent polypeptide-associated complex subunit beta-1", "aln": "--------------------------------------------MPIDQEKLAKLQKLSANNKVGGTRRKLNKKAGSSAGANKDDTKLQSQLAKLHAVTIDNVAEANFFKDDGKVMHFNKVGVQVAAQHNTSVFYGLPQEKNLQDLFPGIISQLGPEAIQALSQLAAQMEKH----EAKAPADAEKKDEAIPELVEGQTFDADVE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** **.* ::**. .** *:.*** .* ** .* .: *.*::..:*.*:***. .* : * : * : : : : *.: .***.: : * ** : . : : .: ::::. ", "identical_positions": 34, "similar_positions": 45, "identity": "15.6%" }, { "cls_id": "homologset.agr.FB:FBgn0000182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Y0-1", "uniprot_id": "A0A0G2K0Y0_RAT", "id": "A0A0G2K0Y0-1", "name": "", "aln": "--------------------------------------------------------------------------------MAAQGEPGYLAAAQSDPGSNSERSTD-----------SPVAGSEDDLVAAAPLLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEAVKEAKEMIMAVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEDTGCHIHFPDSNR-NNQVEKSNQVSIAGQPAGVESARARIRELLPLVLMFELPIAGILQPVPDPNTPSIQHISQTYSVSVSFKQRSRMYGATVIVRGSQNNTNAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNVKHIMQRTGAQIHFPDPS-----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEDIDVDPQVITQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVSIATSLS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPN---------SLLNALN--SSVSPLQSSSSGTPSPTTLWASSIPNTASATGFSTIPHLMIPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKNISASINGHVQPPNMKYGPLSTSSLGEKVLSSNHGDPSMQTAGPEQASPKSNSVEGCNDAFVEVGMPRSPSHSGNAGDLKQMLGPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDTELSATESPLADKKAPGSERAAERAAAAQQ------------NSERARLASQPPYVH-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTAYEGSSLSLSRS-----SSREHLASGSESDNWRDRN------GIGPMGHSEFSAPIGSPKRKQNKSREHYLSSSNYMDCISSLTGSNGCNLNSCFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELSKNRRKLFEPPNTPTTCTSFLEGGVSGRLPRQYHSDIASV-SGRW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MQ1-1", "uniprot_id": "BICC1_MOUSE", "id": "Q99MQ1-1", "name": "Protein bicaudal C homolog 1", "aln": "--------------------------------------------------------------------------------MASQSEPGYLAAAQSDPGSNSERSTD-----------SPVAGSEDDLVAAAPLLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEDTGCHIHFPDSNR-NNQAEKSNQVSIAGQPAGVESARARIRELLPLVLMFELPIAGILQPVPDPNTPSIQHISQTYSVSVSFKQRSRMYGATVTVRGSQNNTNAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNVKHIMQRTGAQIHFPDPS-----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEDIEVDPQVIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVSIATSLS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSATPN---------SLLNALN--TSVSPLQSSSSGTPSP-TLWAPPIANTASATGFSTIPHLMLPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKNISASINGHVQPANMKYGPLSTSSLGEKVLSSNHGDPSMQTAGPEQASPKSNSVEGCNDAFVEVGMPRSPSHSGNAGDLKQMLGASKVSCAKRQTVELLQGTKNSHLHGTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQ------------KSERARLASQPTYVH-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTAYEGSSLSLSRS-----SSREHLASGSESDNWRDRN------GIGPMGHSEFSAPIGSPKRKQNKSREHYLSSSNYMDCISSLTGSNGCNLNSCFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELSKNRRKLFEPPN--ASCTSFLEGGASGRLPRQYHSDIASV-SGRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H694-1", "uniprot_id": "BICC1_HUMAN", "id": "Q9H694-1", "name": "Protein bicaudal C homolog 1", "aln": "--------------------------------------------------------------------------------MAAQGEPGYLAAQ-SDPGSNSERSTD-----------SPVPGSEDDLVAGA-TLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNR-NNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPS-----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPN---------SLLNALN--SSVSPLQSPSSGTPSP-TLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQ------------NSERAHLAPRSSYVN-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRS-----NSREHLGGGSESDNWRDRN------GIGPGSHSEFAASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPN---ARTSFLEGGASGRLPRQYHSDIASV-SGRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HRB2-1", "uniprot_id": "A0AC58HRB2_DANRE", "id": "A0AC58HRB2-1", "name": "", "aln": "-----------------------------------------------------------------------------------MAEP--LSFMHHDHGSSSERSDD-----------SPSAVSEDDSSGHCGHISPPDP-DWTEERFRVDRKKLETMLLAANEGR-INGDD-FFQKVMDETNTQIAWPSKLKIGAKSKKDPHIKVSGKRDDVREAKEKIMSVLDTKSHRVTLKMDVSHTEHSHVIGKGGHNIKRVMEETGCHIHFPDSNR-HSQAEKSNQVSIAGQLTGVEAARVKIRELLPLVLMFEC--SGVVQLV-DCSSPVVQHISHTYNVSISFRPPSRLYGNTAIVRANQNNSSGVKRGTALLLEHLAGSLASSVLVSTQLDIAPQHHHFLLGRNGANIKLISQRTGAHIHFPEISP-H-NSNASRSAVYIQGSIDAVCAARQQIMGCLPLVLLFDIKEETEVASQVITTLMEQLDVFISIKPKPKQPSKSVIVKSVERNAGSLYEVRRILLGLESSCLSSSVSSVSVNGHISSSPPRIASIGLDTLASAGLRLSTLAGLLRSSVSPVPNGSPNPSCALNGHGSVLNIQNGVNNTQHIHTPAHTHSHTPSLWASALSSAADAAGFS--TDLMLQSVSQATLGGLLLSGVQSQAHAHTPSPPPGLAPIHKTVS---------AEHLNGHLASS--VYSRISSVSL-----NSAHCDMAQEGIGHTQSEAKS--TDEGSDTFVEVGMPRSPSHSANGSELKQMLASCTVSPGKRQTVELLQRTKNTLLH-VECVLAD----SDDNPMTDKRAPGSERAAERRLAPHMQVYMLMCKHCTHNSAQTKSHSQCLCVNIFQAFDYEKKKLLATKAMLKKPVVTEIRTPTNTWSGLGFSKSMPAESIKELRRAHHVPYKPSMGTTYEDSHLSMSHS-----GIQEGLINDTKSDNWGDLNGNVNINGNGPSGNSEFSQTVSSTKRIKNKSREQYLSSSNYMDSIS-LTGSNGISLSSSLKGTDLPELFSKLGLGKYTDIFQQQEIDLQTFITLTDPDLKELGITTFGARRKMLLAISELNKSRRKLFDTAN---IRSSFLEGGASGRLTRHFHSDMASV-SGRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H5X5-1", "uniprot_id": "A0AC58H5X5_DANRE", "id": "A0AC58H5X5-1", "name": "", "aln": "MFAVFSSDYITAHSETVALDTFLEIMYYVARVCPVTQHKLADLEHREKLTTMTVFDSDQERFRKAGWGCFRTPLFLVSLVTPPDTDTHSLAMAASETSSTVPESPEPEPCDTTQAELNQDEEDEEDEASEAQQQEPSDP-DSVEERFRIDRKKLEIMLYAPTEASGLSGEE-FFEKVMRETNTQVKWPSKLKIGAKSKKDPHVKVEGKRANVLEAKRKILELLETKVNKVTLKMDVTHTEHSHVIGKGGGNIKKVMEETSCHIHFPDSNRSNSSGEKSNQVSIAGPVEGVESARKQIRDLQPLVLTFDLPVTLAGGVVADTSSPVIQHVAQAFGVTVSFRTQPKLYCSTCSVRGVTANTAALKKAICVLMELLLGSGVNGVMVSTQLDVTSQQHLFLLGQNGANFLTVMHQTHTQIILPDLS-----SPQHTPSLLIQGTADGVCLARQQLMDCLPVCLMFDLKDEGESDPRRFTQMMQNLGVFISVKPKVKQTAKSVVVKGLERNIVNVYEARRLLLGLDSTEVSVSTKSV-------CEVSVMSKHSVDPLLAN-------------------NGITG---------YWLNVLM--------------------------------------QQLRLTDTGSVSIPDAVIGSLSGKPRP-TPPPPPGLA-----------------------VSSEDGRIGLKGVESKLEKILENED--QQTQAESETCSMSHSEVTDVREVIVKPTPSSRRGSQSESSREFNQPITSERLVRADVESVYLNR---------------------------------DRRCSLRIFPSMD-------------------------IN-NEDHEYERKKLLANQAMQQKPVVTEVRTPTDTWSGLGFSKSMPTDAVKELRAVSRRCYRPYNNSNNNNNNNHHSQQQQQSWSGKEHGWTGSDSENWRERR---------GSASSSPPPSSSSYSLSASRSSDVFLTEGGATVSRHLIGRS-----PSPAHADDLIELLAQLGLEKYIDIFQQQEIDYQTFLTLSDEDLKEVGVSTFGARRKMLLAIADLSK-KRKIPEAFV---VKSGYLEGGASGRLPRIMDEDVAAK-SNRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24009-1", "uniprot_id": "BICC_DROME", "id": "Q24009-1", "name": "Protein bicaudal C", "aln": "---------------------------------------------------MLSCASFNKLMYPSAADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQS------EISSVDSDWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNR-SNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSD-MNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDNHN-DASEIMSLNTKYGVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDYYFMP-KDKDLNLAYRTQLTALLAGYVDSPKTPSLLPPSLAGQLTPYAN------NNHLLLNANG--------------------------LATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVS---------PRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVGGGGGGGARLGRRLSDGVLLGLSNSNGGGGNSGGAHLLPG----------------------SAESYRSLHYDLGGNK-------------------------HSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLEN--------------------------------GENGAAGGGASSGWRLPP--------GLGSPYGLSATTGLLDATPVNRR------------------------MQLAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEAACSTMPS-----SSSSQNSSSPRFSGSAAPGAERRPSNQW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07834-1", "uniprot_id": "YL032_YEAST", "id": "Q07834-1", "name": "KH domain-containing protein YLL032C", "aln": "-----------------------------------------------------------------------------------MDNFKIYSTVITTAFLQVPHLYTT----------NRLWKPIEAPFLVEFLQKRISSKELKNTKAICHIDPSWVNLNASFIRDDMISIKATTDDMDLDAICRISLPLPMNTNDLTAELEKMKRILLDLSEKFNLELIITKEPAYFTPEQTGESKELCIYVHALGFRSN----LMECEPQLLAFVDLIK-------KNGMTLPPQHYIIEPMELNSYSVLPLYMGVDMENFKHISRAFKTSIYAPSLITLSR----DLKANPQIFFSGAVHSLSLLARKTLRESISVNSKSFFYRRLTNITPGKLLFIRKYYQQKVN-QLILKYQSLIRVTNEYIEFQSISTNLLEMVIKNFTIQVLHEIVEVQISLNENCAMSPELIIDSFFGHTGNQIVVITPKEDSFNQLIVVGNQ--SSTDEASDTSILHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFEDFISGKKNGKLTRIMELSACLIQLEMEEEDDNLYLNLVSDSFPD------FKESFKNVIN-----------------------------------------EFPAEESFFIPEVCHRPIIGTGGSLIQATMRKHNVFIQFSN---------------SFNLPQNKISMIRYDNVIIRCPRKNKANICLAKNDLKQIVQEYDSLQSKTLIRFSSGQYRHILHVNGQKNIIGQIEKNENVYIMIPLKEPLDGTSQLSIQ------------------------GNDENASRAANELVN--------------------------SAFGYEYEFKIDQEIDPNKEYEFYNLIVVPFLQIMNIIVTFEKDLITFT----------------------------------FEKDTNENTLTKAIELLS-----------NYLETQKTKIIFKKIIKKFVLG-----------------------SASSKSNTSNSNTNGNFRSMNNAKSRTTIDNTSQSGASPQRHKMPVITTVGGAQAIKGYIPNTYYNGYGYGYGYT-------YEYDYNYANSNKAQTNNRHKYQNGRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : . . : * . . ..: : : * :: . : : ::: . *: : . : : :* . :*: : * * : .* ::: :* . ** : .: . . . : : .::. :: . : : . : . : : : : : : : . * * : . * : : * : : * :: .: . : . . * : : ..: ..: : .. . :: :. : * : .. * : . . . . . . . . . .::: * .. . . : .* .: .: : .: . :. . . . . : :. .: . ** : :::.*. : : * . . . ..: ", "identical_positions": 25, "similar_positions": 157, "identity": "2.23%" }, { "cls_id": "homologset.agr.FB:FBgn0000183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZKI9-1", "uniprot_id": "A0A8I5ZKI9_RAT", "id": "A0A8I5ZKI9-1", "name": "", "aln": "-MAAEEALKTV--------DHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLNKILEMQNELKQSRAVVTNVQAENERLSAVVQELKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYISLSD------NHISIS-VEGLKFAED--GSEPNNDDK--MNGHLHGPLGKLNGDYR-----APTARKGESLHP----VSDLFSELNISEIQKLKQQLIQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQNSKELKAELDCEKGRNSAEEAHDYEVDINGLE-ILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTEEKTKYESKIQMYDEQVTNLEKTSKESGEKMAHMEKELQKMTGIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGS---LKGPDDPRGLLSPRLSRR--GVSSPVESRTSSEPVSKE---NTETSKEPSPTKTPTISPVITAPPSS-PVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKG-KLGKSKIGSPKVSGEAPATVPTIDTYLLHSQGPQIPTIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLSVPPDPTSTESFLLKGS----PSMSELIQGHRLSKEKRLTVAPPAKRDCQQPAASVPPQCSQLAGRQDYPTVSPDIALSKEQPHSSSQCAPLHCLAKPPYP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G01-1", "uniprot_id": "BICD1_HUMAN", "id": "Q96G01-1", "name": "Protein bicaudal D homolog 1", "aln": "-MAAEEVLQTV--------DHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDSLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSRAVVTNVQAENERLTAVVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYISLND------NHISIS-VDGLKFAED--GSEPNNDDK--MNGHIHGPLVKLNGDYR-----TPTLRKGESLNP----VSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLE-ILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGS---LKGPDDPRGLLSPRLARR--GVSSPVETRTSSEPVAKE---STEASKEPSPTKTPTISPVITAPPSS-PVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKG-KLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLRVPPDPTSTESFLLKGP----PSMSEFIQGHRLSKEKRLTVAPP---DCQQPAASVPPQCSQLAGRQDCPTVSPDTALPEEQPHSSSQCAPLHCLSKPPHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BR07-1", "uniprot_id": "BICD1_MOUSE", "id": "Q8BR07-1", "name": "Protein bicaudal D homolog 1", "aln": "-MAAEEALKTV--------DQYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLREAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLNKILEMQNELKQSRAVVTNVQAENERLSAVVQELKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLSD------SHISIS-VDGLKFAED--GSEPNNDDK--MNGHIHGPLGKLNGDYR-----TPTTRKGESLHP----VSDLFSELNISEIQKLKQQLIQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQNSKEIKAELDCEKGRNSAEEAHDYEVDINGLE-ILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTEEKTKYESKIQMYDEQVTNLEKTSKESGEKMAHMEKELQKMTGIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGS---LKGPDDPRGLLSPRLSRR--GVSSPVESRTSSEPVSKE---NTETSKEPSPTKTPTISPVITAPPSS-PVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKG-KLGKSKIGSPKIVSS---------------------------------------------------------LLPPYRHSAHN------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7T6T3-1", "uniprot_id": "A0A8N7T6T3_DANRE", "id": "A0A8N7T6T3-1", "name": "", "aln": "MAAGGGCGESV--------DQYRSEVERLTRELAEANREKIRAAECGLVVLEENQKLKHQYAELEIEQEALKQELEQLQEAFGQAYTNQRKVAEDGETNEETLLQESASKEAYYMGRLDDLQSQLKVSSSAASNAQAETEHLNALMQELRENNETLELQRSRMREEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKVLEEETVLLNSQLEDALRLKDISQGQLEEALDSLKSEREQKNNLRKELAHHLSLTDSVYGASTHLAISAVEGLKFAEE--AATNGTSAS--GTSPNNEDSNRCNNECNGHGPKGEYHRRKTEMLP----VSDLFSELNLSEIQKLKQQLIQVEREKALLLTNLQESQTQLQHTQGALTEQHRRVHRLTERVNAMKRLHNDKEFDTE-ESEKGDGPINGCCEFETDINGIE-LLECKYRVAVTEVIDLKAELKVLKEKYNQSLESQSEESNHSDGKVHALEEQVKQLEKSCREARERVSSLEAELRCASGMASESNGMLNAAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGS---LKGPEDPRALLSPRLARRLAAVNSSDMSKSPQDSPSKEPLGDGIKGEGGSPNRTPFGSPINGSSLSSSTIPETGDLRREPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPILDKDKEACMEEILKLKSLLSTKREQIATLRLVLKANKQTAEVALANLKSKYENEKCMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSHCGRGGKVPKIKSSPQKVSLGTALTAP-------------------PSPTASKPPSFPFQNNVVASASSSPSLDVPTPSSSLWTSSTQPFFLGQSQWNLGTQTLVLDPETLSIEFCQVVHSR---DSDAHVARSAPTSPYLGARQQSQRSMRSRIRSDLIQFKTARNSRIPSADPE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LEJ2-1", "uniprot_id": "A0ABK0LEJ2_RAT", "id": "A0ABK0LEJ2-1", "name": "", "aln": "MSAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLINTQSENERLTSVAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNNLRKELSHYMSINDS--FYTSHLQVS-LDGLKFSDDAVTAEPNNDAEALVNGFEHSGLVKASLDNK-----TSTPRKDGLAPPSPSLVSDLLSELHISEIQKLKQQLVQMEREKVGLLATLQDTQKQLEQARGTLSEQHEKVSRLTENLSALRRLQAGKERQTSLDNEKDRDSHEDGDYYEVDINGPE-ILSCKYHVAVAEAGELREQLKALHSTHEAREAQLAEEKGRYEAEVQALTEKVSLLEKASHQDQELLAQLEKELRKVSDVAGETQGSLNVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGKAG------RTSPEGRGRRSPVLLPK--GLLSTEIGR----------------ADGGTGDNSPSPSSSLPSPLSD--------PRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQ---ELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRGRNKATSKAKPATPSCSWFEVLHTN--------------------------------------------------------INNSSPMLP---------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921C5-1", "uniprot_id": "BICD2_MOUSE", "id": "Q921C5-1", "name": "Protein bicaudal D homolog 2", "aln": "MSAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERLTSVAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNNLRKELSHYMSINDS--FYTSHLQVS-LDGLKFSDDTVTAEPNNDAEALVNGFEHSGLVKSSLDNK-----TSTPRKDGLAPPSPSLVSDLLSELHISEIQKLKQQLVQMEREKVGLLATLQDTQKQLEQARGTLSEQHEKVNRLTENLSALRRLQAGKERQTSLDNEKDRDSHEDGDYYEVDINGPE-ILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKISLLEKASHQDRELLAHLEKELKKVSDVAGETQGSLNVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGKAG------RTSPEGRGRRSPVLLPK--GLLATEVGR----------------ADGGTGDNSPSPSSSLPSPLSD--------PRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQ---ELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRGRSKAASKAKPASPSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD16-1", "uniprot_id": "BICD2_HUMAN", "id": "Q8TD16-1", "name": "Protein bicaudal D homolog 2", "aln": "MSAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNSLRKELSHYMSINDS--FYTSHLHVS-LDGLKFSDD--AAEPNNDAEALVNGFEHGGLAKLPLDNK-----TSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGDYYEVDINGPE-ILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGGAGRTSPGGRTSPEARGRRSPILLPK--GLLAPEAGR----------------ADGGTGDSSPSPGSSLPSPLSD--------PRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQ---ELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRGRAKAAPKTKPATPSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16568-1", "uniprot_id": "BICD_DROME", "id": "P16568-1", "name": "Protein bicaudal D", "aln": "MSSASNNGPSADQS----VQDLQMEVERLTRELDQVSSASAQSAQYGLSLLEEKSALQQKCEELETLYDNTRHELDITQEALTKFQTSQKVTNKTGIEQEDALLNESAARETSLNLQIFDLENELKQLRHELERVRNERDRMLQENSDFGRDKSDSEADRLRLKSELKDLKFRETRMLSEYSELEEENISLQKQVSSLRSSQVEFEGAKHEIRRLTEEVELLNQQVDELANLKKIAEKQMEEALETLQGEREAKYALKKELDGHLNRES-----MYHISNLAYSIRSNMED--NASNNSDGE-----EENLALKRLEADLS-------TELKSPDGTK-----CDLFSEIHLNELKKLEKQLESMESEKTHLTANLREAQTSLDKSQNELQNFMSRLALLAAHVDALVQLK--KQIDVK---EQGKEGGQKKDELEQQLRALISQYANWFTLSAKEIDGLKTDIAELQKGLN------------YTDATTTLRNEVTNLKNKLLATEQKSLDLQSDVQTLTHISQNAGQSLGSARSTLVALSDDLAQLYHLVCTVNGETPTRVLLDHKTDDMSFENDS-----LTAIQSQFKSDVFIAK----------------------------------------PQIVEDLQG---------LADSVEIKKYVDTVSDQIKYLKTAVEHTIDMNKHKIRSEGGDALEKVNTEEMEELQEQIVKLKSLLSVKREQIGTLRNVLKSNKQTAEVALTNLKSKYENEKIIVSDTMSKLRNELRLLKEDAATFSSLRAMFAARCEEYVTQVDDLNRQLEAAEEEKKTLNQLLRLAVQQKLALTQRLEEMEMDREMRHVRRPMPAQRGTSGKSSFSTRPSSRNP-------------------------------------------------------ASSNANPF-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : *::**::** :.. . ::*: ** :***: *: : *** : : *:: :**: : : :: . * .*::*::***::* :: :::.:** ..: * ::: .:: . :. * :* *::.:::: ****:*:*.:*:*******:*** ** *:..***:** ****: : **. **.*::: .**.*:: *:****::*: *** * *:*** ::. . *: . . :: : ... . : : : : .**:**:::.*::**::** .:* **. * :.*:::*..*::::. * : :: *: .:.*: *: *: .. *:. : * ::.. : ::. * *: :: *:. : :::. *:: : :: ::: : :: : *. *:. **::*::**:*** ** *.***.**:**: :. . . * : : . .. :.::* : : ****:*: **::: ::.::: :. * :: * *:*:*******.***** *** ***:*********:***.****** :*::** ******: ****************:**:**:**:*:::*** ***:****** ***:*:*********** :*:*:* : : : . . . ", "identical_positions": 241, "similar_positions": 249, "identity": "23.51%" }, { "cls_id": "homologset.agr.FB:FBgn0000212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1P7-1", "uniprot_id": "SMCA4_RAT", "id": "Q8K1P7-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "------------------------------------------------------------------------MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPMPTQGPGGYPQDNMHQMHKPMESMHEKGMPDDPRYN--QMKGMGMRSGAHTGMGPPPSPMDQHSQG----YPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGSDPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKR-----------------PMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP---GGPPKPWPEGPMAN-AAAPTSTPQKLIPPQPTGR--------------PSPAPPAVPPAASPVMPPQTQSPGQPAQPAPLVPLH----QKQSRITPIQKPRGLDPVEILQERE-------------------------------------------YRLQARIVHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE---------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREE------ARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSEAGSSTPTTSTRSRDKDEESKKQK------KRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS------------------GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESE----SRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSDEEQEEDRSGSGSEED-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TKT4-1", "uniprot_id": "SMCA4_MOUSE", "id": "Q3TKT4-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "------------------------------------------------------------------------MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPMPTQGPGGYPQDNMHQMHKPMESMHEKGMPDDPRYN--QMKGMGMRSGAHTGMAPPPSPMDQHSQG----YPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGSDPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKR-----------------PMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP---GGPPKPWPEGPMAN-AAAPTSTPQKLIPPQPTGR--------------PSPAPPAVPPAASPVMPPQTQSPGQPAQPAPLVPLH----QKQSRITPIQKPRGLDPVEILQERE-------------------------------------------YRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE---------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREE------ARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSEAGSSTPTTSTRSRDKDEESKKQK------KRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS------------------GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESE----SRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51532-1", "uniprot_id": "SMCA4_HUMAN", "id": "P51532-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "aln": "------------------------------------------------------------------------MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGP--SPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN--QMKGMGMRSGGHAGMGPPPSPMDQHSQG----YPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKR-----------------PMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP---GGPPKPWPEGPMAN-AAAPTSTPQKLIPPQPTGR--------------PSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLH----QKQSRITPIQKPRGLDPVEILQERE-------------------------------------------YRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKK--AENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--EKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREE------ARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQK------KRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSS-----------------GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE-----------------GEESEEEEEGEEEGSESE----SRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PTG1-1", "uniprot_id": "E9PTG1_RAT", "id": "E9PTG1-1", "name": "", "aln": "------------------------------------------------------------------------MATPTDPA-AMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEGLHQLHKPMDGIHDKGIVEDVHCG--SMKGTSMRP-PHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTP-PQMPPSQPGTLIPG-DLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKR-----------------TLPGMQQQQQQQQQQQQQQQ---------------QQQP-----QQPQQPQQQTQAQPQQQQQQQQQPP---ALVSYNRPSGPGQELLMTAQNTQQKLSAPAPSGR--------------PSPAPPAATQPTATAVPGPSVQQPAPGQPSPVLQLQ----QKQSRISPIQKPQGLDPVEILQERE-------------------------------------------YRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGEPALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESESDYEEEDEEEESSR-------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEY-SMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--ERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENE---------------------------------EEDEVPDDETLNQMIARREEEFDLFMRMDMDRRRED------ARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDP------------VKEDVEKAKK------RRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPCNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESE-----------------EESNEEEEEEDEEESEAE----AKSVKVKIKLNKKEEKGRDTGKGKKRPNRG-KAKPVVSDFDSDEEQDENEQSEASGTDDE---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DIC0-1", "uniprot_id": "SMCA2_MOUSE", "id": "Q6DIC0-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "aln": "------------------------------------------------------------------------MSTPTDPA-AMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPLSTMGSADFPQEGMHQLHKPMDGIHDKGIVEDVHCG--SMKGTSMRP-PHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSS------PTP-PQMPPSQPGALIPG-DPQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKR-----------------TLPGMQQQQQQQQQQQQQQQ---------------QQQQQQQQQQQPQQPQQQAQAQPQQQQQQQQQP----ALVSYNRPSGPGQELLLSGQSAPQKLSAPAPSGR--------------PSPAPQAAVQPTATAVPGPSVQQPAPGQPSPVLQLQ----QKQSRISPIQKPQGLDPVEILQERE-------------------------------------------YRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGEPALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESESDYEEEDEEEESSR-------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEY-SMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--ERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENE---------------------------------EEDEVPDDETLNQMIARREEEFDLFMRMDMDRRRED------ARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDP------------VKEDVEKAKK------RRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKD------------------SSGRQLSEVFIQLPSRKDLPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESE-----------------EESNEEEEEDDEEESESE----AKSVKVKIKLNKKEEKGRDTGKGKKRPNRG-KAKPVVSDFDSDEEQEENEQSEASGTDNE---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51531-1", "uniprot_id": "SMCA2_HUMAN", "id": "P51531-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "aln": "------------------------------------------------------------------------MSTPTDPG-AMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCG--SMKGTGMRP-PHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTP-PQMPPSQPGALIPG-DPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKR-----------------TLPGLQQQQQQQQQQQQQQQ---------------QQQQ------QQQQPQQQ---PPQPQTQQQQQP----ALVNYNRPSGPGPE--LSGPSTPQKLPVPAPGGR--------------PSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQ----QKQSRISPIQKPQGLDPVEILQERE-------------------------------------------YRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSR-------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEY-SMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTG--ERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENE---------------------------------EEDEVPDDETLNQMIARREEEFDLFMRMDMDRRRED------ARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDP------------AKEDVEKAKK------RRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESE-----------------DESNEEEEEEDEEESESE----AKSVKVKIKLNKKDDKGRDKGKGKKRPNRG-KAKPVVSDFDSDEEQDEREQSEGSGTDDE---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25439-1", "uniprot_id": "BRM_DROME", "id": "P25439-1", "name": "Brahma chromatin-remodeling complex ATPase subunit", "aln": "------------------------------------------------------------------------MASPSPANSPMPPP-----QAPSPMAPPSQSPAPSPHSPYPHQQPGPLQGPPPPGHPGAYGHPMQHGPPGQGPPGHHMPPHHQGMIFSKGPHMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIVSPGGPPGGPPPPERSSQENLHALQRAIDSMEEKGLQEDPRYSQLLAMRATSK-HQHLNGNQVNLLRTQITAYRLLARNKPISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGSQHAGQPPVPPQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQQGQPLPPQPPQVGGPPPIQQQQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVRGTLPGMPPGSQVPQPGGGPQRQVPPAGMPMPKPNRITTVAKPVGLDPITLLQERE-------------------------------------------NRIAARISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRRDTTLETALNIKLYKRTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQLARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQTDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSG-EYIG-----IDEGSIVADMRVHVVEQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWID-DEEDSCGSNDDHKPKVEEQPT----------ATEDATDKAQATGNDEDAKDLITKAKVE-DDEY------RTEEQTYYSIAHTIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTG--EKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALMNTIVQLRKLCNHPFMFQHIEEKYCDHTG-GHGVVSGPDLYRVSGKFELLDRILPKLKATNHRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEE--------------------------------EEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKED------EEIHPGRERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAIDDGAEFDEEEEEDDSKRKRRKRKNRKE------------ESDDDSLILK------RRRRQNLDKRS------KKQMHKIMSAVIKHNQD-------------------GRTLSEPFMKLPSRQRLPDYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQRITAAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGDDGSDDEEIATTSAAAVKMKLKLNKSLASAPATPTQSSSNVSSGAATTSKKQTRRKRSQKKYTISDDDDDDMD-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22082-1", "uniprot_id": "SNF2_YEAST", "id": "P22082-1", "name": "SWI/SNF chromatin-remodeling complex subunit SNF2", "aln": "MNIPQRQFSNEEVNRCYLRWQHLRNEHGMNAPSVPEFIYLTKVLQFAAKQRQELQMQRQQQGISGSQQNIVPNSSDQAELPNNASSHISASASPHLAPNMQLNGNETFSTSAHQSPIMQTQMPLNSNGGNNMLPQRQSSVGSLNATNFSPTPANNGENAAEKPDN----SNHNNLNLNNSELQPQNRSLQEHNIQDSNVMPGSQINSPMPQQAQMQQAQFQAQQAQQAQQAQQAQQAQARLQQGRRLPMTMFTAEQSELLKAQITSLKCLVNRKPIPFEFQAVIQKSIN----------------HPPDFKRMLLSLSEFARRRQPTDQNNQSNLNGGNNTQQPGTNSHYNNTNTDNVSGLTRNAPLDSKDENFASVSPAGPSSVHNAKNGTLDKNSQTVSGTPITQTESKKE-------------ENETISNVAKTAPNSNKTHTEQNNPPKPQKPVPLNVLQDQYKEGIKVVDIDDPDMMVDSFTMPNISHSNIDYQTLLANSDHAKFTIEPGVLPVGIDTHTATDIYQTLIALNLDTTVNDCLDKLLNDECTESTRENALYDYYALQLLPLQKAVRGHVLQFEWHQNSLLTNTHPNFLSKIRNINVQDALLTNQLYKNHELLKLERKKTEAVARLKSMNKSAINQYNRRQDKKNKRLKFGHRLIATHTNLERDEQKRAEKKAKERLQALKANDEEAYIKLLDQTKDTRITHLLRQTNAFLDSLTRAVKDQQKYTKEMIDSHIK--------------------------------------------------------------------------------------------------------------EASEEVDDLSMVPKMKDEEYDDDDDN--------SNVDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLFIG-DQNNKKMVG-LRGFNNQIMQLKKICNHPFVFEEVEDQINPTRE------TNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRESG--------------------------VEEEEELKDSEINEILARNDEEMAVLTRMDEDRSKKE------EELGVKS-RLLEKSELPDIYSRDIGAELKREESESAAVYNGRGARERKTATYNDNMSEEQWLRQFEVSDDEKND--KQARKQRTKKEDKSEAIDGNGEIKGENIDADNDGPRINNISAEDRADTDLAMNDDDFLSK-KRKAGRPRGRPKKVKLEGSENS--EPPALESSPVTGDNSPSEDFMDIPKPRTAGKTSVKSARTSTRGRGRGRGRGRGRGRGRGRPPKARNGLDYVRTPAAATSPIDIREKVAKQALDLYHFALNYENEAG----------------RKLSDIFLSKPSKALYPDYYMIIKYPVAFDNINTHIETLAYNSLKETLQDFHLIFSNARIYNTEGSVVYEDSLELEKVVTKKYCEIMGDNSQLDFTEFDEQYGTRPLVLPPVVTSSVAESFTDEADSSMTEASV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32597-1", "uniprot_id": "STH1_YEAST", "id": "P32597-1", "name": "Nuclear protein STH1/NPS1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MLQEQSELMSTVMNNTPTTVAALAAVAAASETN----GKLG------SEEQPE-------------------ITIPKPRSSAQLEQLLYRYRAIQNHPKENKLEIKAIEDTFRNISR------DQDIYETKLDTLRKSIDKG---FQYDEDLLN-------------------------KHLVALQLLEK-----------------DTDVPDYFLDLPDTKNDNTT---------AIEVDYSEKKPIKISADFNAKAKSLGLESKFSN-------ATKTA-------------LGDPDTEIRISARISNRINELER--------LPANLGTYSLDDCLEFITKDDLSSRMDTFKIK---------------------------------------ALVELKSLKLLTKQKSIRQKLINNVASQAHHN-----------IPYLRDS------------PFTAAAQRSVQIRSKVIVPQTVRLAEELERQQLLEKRKKERNLHLQKINSIIDFIKERQSEQWSRQERCFQFGRLGASLHNQMEKDEQKRIERTAKQRLAALKSNDEEAYLKLLDQTKDTRITQLLRQTNSFLDSLSEAVRAQQNEAKILHG---------------------------------------------------------------------------------------------------------------------------EEVQPITDEERE--------------KTDYYEVAHRIKEKIDKQPSILVGGTLKEYQLRGLEWMVSLYNNHLNGILADEMGLGKTIQSISLITYLYEVKKDIGPFLVIVPLSTITNWTLEFEKWAPSLNTIIYKGTPNQRHSLQHQIRVGNFDVLLTTYEYIIKDKSLLSKHDWAHMIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLPELWALLNFVLPKIFNSAKTFEDWFNTPFANTGTQEKLELTEEETLLIIRRLHKVLRPFLLRRLKKEVEKDLPDKVEKVIKCKLSGLQQQLYQQMLKHNALFVG-AGTEGATKGGIKGLNNKIMQLRKICNHPFVFDEVEGVVNPSRG------NSDLLFRVAGKFELLDRVLPKFKASGHRVLMFFQMTQVMDIMEDFLRMKDLKYMRLDGSTKTEERTEMLNAFNAPDSDYFCFLLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVEEVILERAMQKLDIDGKVIQAGKFDNKSTAEEQEAFLRRLIESETNRDD--------------------------------DDKAELDDDELNDTLARSADEKILFDKIDKERMNQERADAKAQGLRVPPPRLIQLDELPKVFREDIEEHFKKEDSE----PLGR-IRQKKRVYYDDGLTEEQFLEAVEDDNMSLEDAIKKRREARERRRLRQNGTKENEIETLENTPEASETSLIENNSFTAAVDEETNADKETTASRSKRRSSRKKRTISIVTAEDKENTQEESTSQENGGAKVEEEVKSSSVEIINGSESKKKKPKLTVKIKLNKTTVLENNDGKRAEEKPESKSPAKKTAAKKTKTKSKSLGIFPTVEKLVEEMREQLDEVDSHP-------------------RTSIFEKLPSKRDYPDYFKVIEKPMAIDIILKNCKNGTYKTLEEVRQALQTMFENARFYNEEGSWVYVDADKLNEFTDEWFKEHSS----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . .::: : : : : : . . . . : . : : : : : . : : . : : : .: : : . : : : . :::* ::: : .:.: : :: . : . : . : :: : * : *::::*. *: *:*: * ::***.* **:**.** *:: ** **: :: .*:. * :: . : : : ** :** : * : :*.::::.*.**.**::**:*:***:**:****************:*:*:*** : *. **:*:******:.** ** ****:: : :**:* *: ::* :*:*:***:**:**:: :*:* * :**:******** :.**: .:. :* : *::********:**********:**.**:* .:*::***:*** ** ::::*.****:*:******************:** :**:*** ::**.:*.**: :*::* *: . . * : : * *:**:*:****::*:.:* . ::*.:********:***::*:.*:**:* ***. * *:**:: : *:**** **:::* :*. ** .*: : *:*************:****:***:*******************:****:*** *.:**** ** * **::* ****** **:**:. *:. :*: ::. : : ::. .*. :* :** :* :: ::* :* .:: **:: .***. .* : . ** *.:: . * * ::*:::*. .: . : : ::. . . : . . .:: . . .. :.: . . : .. . .: . : . : . . .. . . . . .. . . . . : : . ", "identical_positions": 323, "similar_positions": 323, "identity": "16.86%" }, { "cls_id": "homologset.agr.FB:FBgn0000221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9C0J1-1", "uniprot_id": "B3GN4_HUMAN", "id": "Q9C0J1-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4", "aln": "------MLPPQPSAAHQGRGGRSGLLPKGPAMLCRLCWLVSYSLAVLLLGCLLFLRKAAKPAGDPTAH-------------------------QPFW------APPTPRHSRC-----PPNHTVSSASLS---------------------LPSRHRLFLTYRHCRNFSILLE-P-SGCS------KDTFLLLAIKSQPGHVERRAAIRSTWGRVGGWAR-GR-QLKLVFLLGVAG----------SAPP----AQLLAYESREFDDILQWDFTEDFFNLTLKELHLQRWVVAACPQAHFMLKGDDDVFVHVPNVLEFLDGWDP--AQDLLVGDVIRQALPNRNTKVKYFIPPSMYRATHYPPYAGGGGYVMSRATVRRLQAIMEDAE-LFPIDDVFVGMCLRRLGLSPMHHAGFKTFGIRRPLDP-----LDPCLYRGLLLVHRLS-PLEMWTMWALVTDEG-LKCAAGPIPQR----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LUZ3-1", "uniprot_id": "A0ABK0LUZ3_RAT", "id": "A0ABK0LUZ3-1", "name": "Hexosyltransferase", "aln": "-------------------------------MLRRLGCVLFCTLVVLLLGCLLFL-KERTPAGSSEAH-------------------------QHFL------APPRPHHSQC-----SPNLTVVNTSLS---------------------LPSRHRLFLTYRHCRNFSILLE-P-SECA------RDIFLLLVIKSQPAHIEQRAAIRSTWGRGGSWAR-GR-QLKLVFLLGVAG----------PVPP----AQLLAYESWQFDDILQWDFAEDFFNLTLKELHVQRWIAAACTQAHFILKGDDDVFIHVPNVLEFLEGWDP--AQDLLVGDVIRLARPNRNTKVKYFIPFSMYRARHYPPYAGGGGYVMSQATVRHLHTAMEEAE-LFPIDDVFVGMCLRKLGVTPIHHAGFKTFGIQQPLNP-----RDPCLYRGLLLVHRLS-PLEMWTMWALVTDER-LECAARKP-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66H69-1", "uniprot_id": "B3GN7_RAT", "id": "Q66H69-1", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7", "aln": "--------------------MSLWKKTLYKSVCLALALLVAVTVFQRSVTPGQFLQDPLPPTLGPPKT----G---------------SLVNPNSFWKSSKDVVAPTPTVPRG-----PQVWDVVTTNCSIN--------VNLTHQPWFQNLEPHFRQFLAYQHCRYFPMLLNHP-EKCA------GDVYLLVVVKSVITQHDRREVIRQTWGHEWESAGPDRGAVRTLFLLGTAS----------KQEERTHYQQLLAYEDRLYGDILQWDFLDSFFNLTLKEIHFLKWLDIYCPNVPFIFKGDDDVFVNPTNLLEFLSDRQP--QENLFVGDVLKHARPIRKKDNKYYIPAVMYSKATYPPYAGGGGFLMSGSLARQLHHACDTLE-LFPIDDVFLGMCLEVLGVKPTGHEGFKTFGISRVRGSRMN--KEPCFYRSMLVVHKLL-PAELLAMWDLVHSN--LTCSLKFQVL-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0J2-1", "uniprot_id": "B3GN7_MOUSE", "id": "Q8K0J2-1", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7", "aln": "--------------------MSLWKKTLYKSVCLALALLVAVTVFQRSVTPGQFLQDPLPPTPGPAKT----G---------------NLVNPNSFWKSSKDVAAPTPTVPRG-----PQVWDVITTNCSIN--------INLTHQPWFQSLEPHFRQFLAYRHCRYFPMLLNHP-EKCA------GDVYMLVVVKSVITQHDRREVIRQTWGHEWESAGLGRGAVRTLFLLGTAS----------KQEERTHYQQLLAYEDRLYADILQWDFLDSFFNLTLKEIHFLKWLDIYCPNVPFVFKGDDDVFVNPTNLLEFLSDRQP--QENLFVGDVLKHARPIRKKDNKYYIPAVMYGKATYPPYAGGGGFLMSGSLARQLHHACDTLE-LFPIDDVFLGMCLEVLGVKPTGHEGFKTFGISRVRSSRMN--KEPCFYRAMLVVHKLL-PAELLAMWDLVHSN--LTCSVKFQVL-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFL0-1", "uniprot_id": "B3GN7_HUMAN", "id": "Q8NFL0-1", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7", "aln": "--------------------MSLWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNG---------------QLVNPNNFWKNPKDVAAPTPMASQG-----PQAWDVTTTNCSAN--------INLTHQPWFQVLEPQFRQFLFYRHCRYFPMLLNHP-EKCR------GDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTAS----------KQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQP--QENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLE-LYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRMN--KEPCFFRAMLVVHKLL-PPELLAMWGLVHSN--LTCSRKLQVL-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6UX72-1", "uniprot_id": "B3GN9_HUMAN", "id": "Q6UX72-1", "name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9", "aln": "---------------------MRRRLRLRRDALLTLLLGASLGLLLYAQR-----DGAAPTASAPRGRGRAAP---------------RPTPGPRAFQLP-DAGAAPPAY---------EGDTPAPP---------------------TPTGPFDFARYLRAKDQRRFPLLINQP-HKCRGDGAPGGRPDLLIAVKSVAEDFERRQAVRQTWGAEGRVQGAL---VRRVFLLGVPRGAGSGGADEVGEGARTHWRALLRAESLAYADILLWAFDDTFFNLTLKEIHFLAWASAFCPDVRFVFKGDADVFVNVGNLLEFLAPRDP--AQDLLAGDVIVHARPIRTRASKYYIPEAVYGLPAYPAYAGGGGFVLSGATLHRLAGACAQVE-LFPIDDVFLGMCLQRLRLTPEPHPAFRTFGIPQPSAAPHLSTFDPCFYRELVVVHGLS-AADIWLMWRLLHGPHGPACAHPQPVAAGPFQWDS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K1Q3-1", "uniprot_id": "A0A0G2K1Q3_RAT", "id": "A0A0G2K1Q3-1", "name": "Hexosyltransferase", "aln": "---------------------MRRRPRLCRDAWLTLLLSAALGLLLYAQR-----DGVSPTTRAPPARGRQLP---------------RPTPGRRALELPNTAHAAPPAY---------EGETPVPP---------------------TPTDPFDFRRYLRAKDQRRFPLLINQP-RKCHSDGASGGSLDLLIAVKSVAADFERREAVRQTWGAEGRVQGAL---VRRVFLLGVPKGAGSG-----GAGTRTHWRALLEAESRAYADILLWAFEDTFFNLTLKEIHFLSWASAFCPDVHFVFKGDADVFVHVRNLLQFLEPRDP--AQDLLAGDVIVQARPIRARASKYFIPQAVYGLPVYPAYAGGGGFVLSGATLHRLAHACTQVE-LFPIDDVFLGMCLQRLRLTPEPHPAFRTFGISQPSAAPHLRTFDPCFYRELVVVHGLS-AADIWLMWRLLHGPQGPVCAHPQPVATGPFQWNS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PD09-1", "uniprot_id": "A0A8M9PD09_DANRE", "id": "A0A8M9PD09-1", "name": "Hexosyltransferase", "aln": "----------------------MRRVYLKGDVLCSLTLMLLLFLLLYAYQRVTPTWGTLHIEHGPTSSRTLLS---------------GASMGQQTKLVPTKSLDIPPCQPEVQTKSKPQGQSKVKPQKARSKTKSKFQQASTTASLLPTQHSFDFADYLRKKDQRDFKMLIDQP-TKCS---EPESAPYMLIAIKSVTTDFDKRQVVRRTWGREGVFQKNIN--IKRVFLLGVPQ----------NQSALPLWDKLLEYESHTFGDILLWDFEDTFFNLTLKEIHFLQWINVSCPKTKFIFKGDADVYVNIDNILEMLESQEI--DKDLFVGDIIVHAKPIRRRSSKYFVPEFIYGQGIYPSYAGGGGFVMSGHTALKLHLACKEVE-LFPIDDVFLGMCLLRIGLQPTRHEGFRTFGIVKPSAAPHLQVFDPCFYRELMVVHSLT-VPQIWLMWNLLHDPN-LRCHRSQDPTVFPFQWSEKIGKTARNKAEENLRNKDYGMKVFVEH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZC66-1", "uniprot_id": "D3ZC66_RAT", "id": "D3ZC66-1", "name": "Hexosyltransferase", "aln": "--------------------MALPCSRRSKTPKTLAFLLVGMTFVVLNQWL---LQEPM---REKANGSVVTP---------------WSSEAAVLRLP---LLPAPPCAAN-------VSVDLLDG---------------------FQELPARIQDFLRYRHCRRFPQLWDAP-HKCVGPR----GVFLLLAVKSSPAHYERRELIRRTWGQERSYSGQQ---VRRLFLVGTSSPE--------EAAREPQLADLLSLEAREHGDVLQWDFKDTFLNLTLKHLHLLDWTEEHCPGMSFLLSCDDDVFVHTANVLRFLEVQSP--ERHLFTGQLMAGSVPIRESWSKYFVPRQLFPGTAYPVYCSGGGFLMSRRTAQDLRRASHHVP-LFPIDDAYMGMCLQQAGLAPSNHEGIRPFGVQLPGTKRSS--FDPCMYRELLLVHRFA-PYEMLLMWKALHDPA-LQCSHRQDAGSPEARGEMISDAH----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3USF0-1", "uniprot_id": "B3GN6_MOUSE", "id": "Q3USF0-1", "name": "Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase", "aln": "--------------------MALPSSRRFKSPTTLAFFLVGVTLVVLNQWF---LQEHR---QEKAKGPVATR---------------RSLAAVVQRSP---LFQVPPCVAN-------ASANLLTG---------------------FQLLPARIQDFLRYRHCRRFPQLWDAP-PKCAGPR----GVFLLLAVKSSPAHYERRELIRRTWGQERSYSGRQ---VLRLFLVGTSPPE--------EAAREPQLADLLSLEAREYGDVLQWDFSDTFLNLTLKHLHLLDWTAEHCPGVSFLLSCDDDVFVHTANVLSFLEVQSP--EHHLFTGQLMVGSVPVRESGSKYFVPPQIFPGVAYPAYCSGGGFLLSRYTVRNLRSAAHHVP-LFPIDDAYMGMCLQQAGLAPSSHQGIRPFGVQLPNVQRLS--LDPCMYRELLLVHRFA-PYEMLLMWKALHNPA-LHCSHKQVAGSPTA-GEQNPDAH----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMB0-1", "uniprot_id": "B3GN6_HUMAN", "id": "Q6ZMB0-1", "name": "Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase", "aln": "--------------------MAFPC-RRSLTAKTLACLLVGVSFLALQQWF---LQAPRSPREERSPQEETPE---------------GPTDAPAADEPPSELVPGPPCVAN-------ASANATAD---------------------FEQLPARIQDFLRYRHCRHFPLLWDAP-AKCAGGR----GVFLLLAVKSAPEHYERRELIRRTWGQERSYGGRP---VRRLFLLGTPGPE--------DEARAERLAELVALEAREHGDVLQWAFADTFLNLTLKHLHLLDWLAARCPHARFLLSGDDDVFVHTANVVRFLQAQPP--GRHLFSGQLMEGSVPIRDSWSKYFVPPQLFPGSAYPVYCSGGGFLLSGPTARALRAAARHTP-LFPIDDAYMGMCLERAGLAPSGHEGIRPFGVQLPGAQQSS--FDPCMYRELLLVHRFA-PYEMLLMWKALHSPA-LSCDRGHRVS-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZX31-1", "uniprot_id": "D3ZX31_RAT", "id": "D3ZX31-1", "name": "Hexosyltransferase", "aln": "--------------------MRLPR---LRP---VVSLLLALAALLLLLTC---QSPPSCPAPESPTEPKDDP---------------AWAPDLSRAHA-------APCRAN-------LSVSAHPA---------------------FARLPSHVRDFLLYRHCRDFAVLREPKATKCAQP------AFLLLAIKSSPANYGRRQVLRTTWARERRVRGAS---LRRLFLVGSDRDP--------QQAR--KFNRLLELEAKAYGDILQWDFHDSFFNLTLKQVLFLEWQRTHCTNASFVLNGDDDVFAHTDNMVTYLQGRDP--DQHLFVGHLIQNVGPIRVPWSKYFIPTLVTAEDKYPPYCGGGGFLLSRFTMAALHRAARVLP-IFPIDDVFLGMCLQQQGLAPGAHSGVRTAGVLPPSPRVSS--FDPCFYRDLLLVHRFL-PFEMLLMWDALSRPQ-LACGRQSPPLLTGLGGRHP--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JCS9-1", "uniprot_id": "B3GN3_MOUSE", "id": "Q5JCS9-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3", "aln": "--------------------MRLPR---QSPYEILLLVLVALLVLLLLLTS---KSPPSCSAPERSKEPEDNP---------------GWATGHPRTHP-------ARCRAN-------LSVSSHPD---------------------FAGLPLHVRDFLFYRHCRDFPVLREPRVTKCAEP------VFLLLAIKSSPANYGRRQMLRTTWARERRVRGAP---LRRLFLVGSDRDP--------QQAR--KYNRLLELEAQKYGDILQWDFHDSFFNLTLKQVLFLEWQLTYCTNASFVLNGDDDVFAHTDNMVTYLQDHDP--DQHLFVGHLIQNVGPIRVPWSKYFIPALVMAEDRYPPYCGGGGFLLSRFTVAALRRAARVLP-MFPIDDVFLGMCLQQQGLAPGTHSGVRTAGVFPPSPRVSS--FDPCFYRDLLLVHRFL-PFEMLLMWDALNQPQ-LLCGRQSPAY-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2A9-1", "uniprot_id": "B3GN3_HUMAN", "id": "Q9Y2A9-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3", "aln": "--------------------MKYLR---HRRPNATLILAIGAFTLLLFSLL---VSPPTCKVQEQPPAIPEAL---------------AWPTPPTRPAP-------APCHAN-------TSMVTHPD---------------------FATQPQHVQNFLLYRHCRHFPLLQDVPPSKCAQP------VFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQ---LRLLFLVGTASNP--------HEAR--KVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDP--GRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLD-IFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSS--FDPCFYRDLLLVHRFL-PYEMLLMWDALNQPN-LTCGNQTQIY-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7Z7M8-1", "uniprot_id": "B3GN8_HUMAN", "id": "Q7Z7M8-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 8", "aln": "--------------------MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPT---------------LPANLSTRLGQTIPLPFAYWNQQQW-RLGSLPSGDSTETGGCQAWG-----AAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWG----SPAPG---IRLLFLLG-SPVG----------EAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEG-GYPAYASGGGYVIAGRLAPWLLRAAARVA-PFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADR-TA------DHCAFRNLLLVRPLG-PQASIRLWKQLQDPR-LQC------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZE36-1", "uniprot_id": "D3ZE36_RAT", "id": "D3ZE36-1", "name": "Hexosyltransferase", "aln": "--------------------MRCRKCQLCLSALLTLLGLKVYIEWTSESWLKKAEP--RGALPSPTPPSAEPT---------------LPTNLSARLGQTGPLSSAYWNQQQR-QLGVLPSSD------CQTWG-----SVAASEILDFILYPQDLRRFLLSAACRSFPLWLPAGEGSPVASCSDKDVPYLLLAVKSEPGHFAARQAVRETWG----SPVAG---TRLLFLLG-SPLG----------MGGPDLTSLVTWESRRYGDLLLWDFLDVPYNRTLKDLLLLTWLSHHCPKVSFVLQVQDNAFVHIPALLEHLQALPPTWARSLYLGEVFTQAKPLRKPGGPFYVPKTFFEG-DYPAYASGGGYVISGRLAPWLLQAAARVA-PFPFDDVYTGFCFRALGLAPRAHPGFLTAWPAER-TR------DPCAVRGLLLVHPVS-PQDTIWLWRHLWVPE-LRC------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PMP9-1", "uniprot_id": "A0A8M9PMP9_DANRE", "id": "A0A8M9PMP9-1", "name": "Hexosyltransferase", "aln": "--------------------MGKKYMKFLIVALASSLCFILFYSKLVDVEITAKDKITSVTASIPRKPTTALVSTIKKQTKGVAPFKLPPLTISNDFRKSVPKNGAFWNRKLHSFLRQLDSADNTTDPRKKFHCSPESFELLKMNIQDVNTYPPLYGDFLRGMECRDSPLVINQPDKCALD--NEDDRIFLLFAIKSTPKHFERRQAVRETWGREGEYDGLK---VRTVFLLG-RSS-----------LDDPNLDKLILSESQHFQDLLVWDFHDSFYNLTLKEHVFFKWMLGHCPRVSFIFKGDDDVFANPQAIINHLTSLEPEQASSLYTGQIISEATPLRDPKTKYCVPLTFYEG-AYPPYAGGGGFLFSGELLPYLYHVSFYIP-FFPIDDVYTGMCFKALGISPMKHDGFRTFDIREQDRE------NPCVHKHLLLVHRRS-PQQTMRLWRSMHSSM-LTC------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZEF9-1", "uniprot_id": "D3ZEF9_RAT", "id": "D3ZEF9-1", "name": "Hexosyltransferase", "aln": "--------------------MSVGRRRVRLLGILMTANVFIYLIVEVSKSSSQDKNG-KGGVIIPKEKFWKLS-----------------SLPRAYWNREQEKLNRWYNPILNRVANQTGDLFTSPNTSHLNYCEPDS--TVMTAVTDFNNLPDRFKDFLLYLRCRNYSLLIDQPKKCAKK-------PFLLLAIKSLIPHFARRQAIRESWGRETNVGNQT---VVRVFLLGKTPPE----------DNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDAEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVFYTG-VYPPYAGGGGFLYSGPLALRLYNVTDRVH-LYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKK------NICSYIDLMLVHSRK-PQEMIDIWSQLQSPN-LKC------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z222-1", "uniprot_id": "B3GN2_MOUSE", "id": "Q9Z222-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2", "aln": "--------------------MSVGRRRVKLLGILMMANVFIYLIVEVSKNSSQDKNG-KGGVIIPKEKFWKPP-----------------STPRAYWNREQEKLNRWYNPILNRVANQTGELATSPNTSHLSYCEPDS--TVMTAVTDFNNLPDRFKDFLLYLRCRNYSLLIDQPKKCAKK-------PFLLLAIKSLIPHFARRQAIRESWGRETNVGNQT---VVRVFLLGKTPPE----------DNHPDLSDMLKFESDKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDAEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVFYTG-VYPPYAGGGGFLYSGPLALRLYSATSRVH-LYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKK------NICSYIDLMLVHSRK-PQEMIDIWSQLQSPN-LKC------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY97-1", "uniprot_id": "B3GN2_HUMAN", "id": "Q9NY97-1", "name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2", "aln": "--------------------MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNG-KGEVIIPKEKFWKIS-----------------TPPEAYWNREQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDL--RVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKCAKK-------PFLLLAIKSLTPHFARRQAIRESWGQESNAGNQT---VVRVFLLGQTPPE----------DNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSG-LYPPYAGGGGFLYSGHLALRLYHITDQVH-LYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKN------NICSYVDLMLVHSRK-PQEMIDIWSQLQSAH-LKC------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B700-1", "uniprot_id": "A0A8M2B700_DANRE", "id": "A0A8M2B700-1", "name": "Hexosyltransferase", "aln": "MDLTLDIPCRCPRCGKGFFKMSNNWNSTKLLGVLMLANFLIYIAVEVSRSHNHDRNAFKKNKMIPKE-FWKKT-----------------KVSTAFWNREQERLDDIYYLPLVNASELPPHFRGIPRWLNHS-CKHDV--NVTAQIEDFNSLPQRFQDFLLYMGCRSYPLITRAPKVCSKP-------PYLLLAIKSLAPHFDRRQAIRESWGRAGILDGQR---IATVFLLGNTAST----------DHFPDLSNMVKHEAELYGDVLQWDYRDTFFNLTLKEVLFLEWFGSHCASAQYVFKGDDDVFVNTRHMLAYLANFSISSTQDLFIGDVITNAGPHRSRQLKYYIPESVFTG-GYPPYAGGGGYLYSGSVGLRLRKISRLVT-LYPIDDVYTGMCLQRLGLVPEKHSGFKTFDIEEKHRE------NPCAYKGLILVHPRS-PQDMIKIWSWINDPN-AICHITSTPKTKKTKYTPL--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99NB2-1", "uniprot_id": "B3GN5_RAT", "id": "Q99NB2-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "aln": "--------------------MRVFVSSRRVKRWQ-FFHLFAICFILSFMVFWGPINNYIMSHMKSYSYRYLIN---------------------------------------------------------------------------SYDFVNDSLSLKHSSVQPHHPYLINHREKCQAQD------VLLLLFIKTAPENYERRSAIRKTWGNENYVQSQLNANIKILFALGTPHPL-----------KGKELQKRLIWEDQVYHDIIQQDFTDSFHNLTFKFLLQFGWANTFCPHARFLMTADDDIFIHMPNLIEYLQGLEQVGVRDFWIGHVHRGGPPVRDKSSKYYVPYEMYKWPAYPDYTAGAAYVVSNDVAAKIYEASQTLNSSMYIDDVFMGLCANKVGVVPQDHVFFS--GEGKIPYH-------PCIYEKMITSHGH--SQDLQDLWVEATDPKVKDISKGFFGQIYCRLIKIVLLCRLTYRNSYPCRAAFA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGY6-1", "uniprot_id": "B3GN5_MOUSE", "id": "Q8BGY6-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "aln": "--------------------MRLFVS-RRVKRWK-IFHFFVTCFILSFMVFWSPINNYIMSHMKSYSYRYLVN---------------------------------------------------------------------------SYGFVNNSLSLKHSSVQPHYPYLINHREKCQAQD------VLLLLFIKTAPENYGRRSAIRKTWGNENYVQSQLNANIKILFALGTPGPL-----------KGKELQKRLIGEDQVYKDIIQQDFIDSFHNLTSKFLLQFSWANTFCPHAKFLMTADDDIFIHMPNLIEYLQGLEQIGVRDFWIGHVHRGGPPVRDKSSKYYVPYEMYKWPAYPDYTAGAAYVVSRDVAAKIYEASQTLNSSMYIDDVFMGLCANKVGILPQDHVFFS--GEGKIPYH-------PCIYEKMMTSHGH--LQDLQDLWIEATHPKVKNISKGFFGQIYCRLIKIVLLCRLTYRNSYPCWAAFA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYG0-1", "uniprot_id": "B3GN5_HUMAN", "id": "Q9BYG0-1", "name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "aln": "--------------------MRMLVSGRRVKKWQLIIQLFATCFLASLMFFWEPIDNHIVSHMKSYSYRYLIN---------------------------------------------------------------------------SYDFVNDTLSLKHTSAGPRYQYLINHKEKCQAQD------VLLLLFVKTAPENYDRRSGIRRTWGNENYVRSQLNANIKTLFALGTPNPL-----------EGEELQRKLAWEDQRYNDIIQQDFVDSFYNLTLKLLMQFSWANTYCPHAKFLMTADDDIFIHMPNLIEYLQSLEQIGVQDFWIGRVHRGAPPIRDKSSKYYVSYEMYQWPAYPDYTAGAAYVISGDVAAKVYEASQTLNSSLYIDDVFMGLCANKIGIVPQDHVFFS--GEGKTPYH-------PCIYEKMMTSHGH--LEDLQDLWKNATDPKVKTISKGFFGQIYCRLMKIILLCKISYVDTYPCRAAFI--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4AB20-1", "uniprot_id": "D4AB20_RAT", "id": "D4AB20-1", "name": "Hexosyltransferase", "aln": "------------------------------MAHMKTRLLYASVLTMGALCLYFSMES----------FQELPF---------------------------------------------------------------------------VFK-KSHG------------KFLQLPEIDCKQKP------PFLVLLVTSSHKQLAARMAIRKTWGRETSVQGQP---VRTFFLLGSS--------------DSTEDMDATALESEQHRDIIQKDFKDAYFNLTLKTMMGMEWVYHFCPQTAYVMKTDSDMFVNVGYLTELLLKKNKTTR--FFTGYIKPHDFPIRQKFNKWFVSKFEYPWDRYPPFCSGTGYVFSSDVAIQVYNVSESVP-FIKLEDVFVGLCLAKLKIRPEELHTKQTFFPGGLRFS-------VCRFQKIVACHFMK-PQDLLTYWQALETSKDEDCPAV---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZPD8-1", "uniprot_id": "D3ZPD8_RAT", "id": "D3ZPD8-1", "name": "Hexosyltransferase", "aln": "------------------------------MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTV---------------------------------------------------------------------------ARKNFTFGNIRTRPINPHSFEFLINEPNKCEKNI------PFLVILISTTHKEFDARQAIRETWGDENNFKGIK---IATLFLLGKN--------------ADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGG-PIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTR-LLHLEDVYVGLCLRKLGIHP---FQNSGFNHWKMAYS-------LCRYRRVITVHQIS-PEEMHRIWNDMSSKKHLRC------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24157-1", "uniprot_id": "BRN_DROME", "id": "Q24157-1", "name": "Beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase brn", "aln": "------------------------MQSKHRKLLLRCLLVLPLILLVDYCGLLTHLHELNFERHFHYPLNDDTG------------------------------------------------------------------------------SGSASSGLDKFAYLRVPSFTAEVPVDQPAR---------LTMLIKSAVGNSRRREAIRRTWGYEGRFSDVH---LRRVFLLGTAEDS----------------EKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQFNRSEFYLFVDDDYYVSAKNVLKFLGRGRQSHQPELLFAGHVFQTSPLRHKFSKWYVSLEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLP-LFRFDDVYLGIVALKAGISLQHCDDFRFHRPAYKGPD---------SYSSVIASHEFGDPEEMTRVWNECRSANYA--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.: * :* :*. .* :* * . *:: : : * : * * : : : : : : * . * * : :. :* : . .:: : : ::*.: *: : :: : * ", "identical_positions": 17, "similar_positions": 43, "identity": "3.34%" }, { "cls_id": "homologset.agr.FB:FBgn0000228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7B7-1", "uniprot_id": "A0A8I6A7B7_RAT", "id": "A0A8I6A7B7-1", "name": "", "aln": "---------------------------------------------------------------MDEVEQDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLCLEDVGP-VLQQTLLQDNLLGRVHFDQFKEALILILSRTLSS-----EEHFEESDCSPEAQPKYVRGGKRYGRRSLPEFQ-------------ESGEEFAEVTVLEPLEEEARPSHIPAGDCSEHWKTQR---SEEYEAEGQLRFWNPDDLNASHGGSCPPPDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPD--GTMSVEDFFYGLFKTGKSLTPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMMSTIG-FRVFSCLDDGMGQASVERILDTWQEEGIENSQEILKA--LDFSLDGNINLTELTLALENELLVTK-----NGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNAL--------------------------SEELDGHGDGIEQDQEPGSGECNPLNMSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQA-------AAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQIEAQFQADCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQRE-KATALARSQEQETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATS-LLVLQGGCRATAGEEAEGNGALSLLQQGEQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQRLKKLEPGSAISSCLEERMTEISGSSREHAEPVMKR-------GTATKHFLSDPGDHEAQGLGSTGTSSVQRQECRTEESEASLECFSELENSEDTRTESWDLKSQIIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDAARENACLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKMEEVTGTFLSLENSYDEVKLENEK---------------LSALVLRLQGKMEEVLERAALQGDSYSLWEGPSENLEVTSDEKMLELHQTEEECTPEVMSRHHIIEECRQETRCCEQGSTQLLAGIKAHEIAWFRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQ------EENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLK--NQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKE-DPGTCTSEKWEQENESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQLHRCPDLSDFQQKMCSILSYNENLLKEKEVLSEELKSCADKLAESSLLEHRI-------ATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQNAIDKDWVSETATHLSGLQGQQKRLSWNKLDHLMSEEPELLCQESKRLQTVVQNTQADLTHSREKIRQLESNLLPTKHQKQLNQSCTVKPIEQEKLALKRECEQSRKERSPTSRKVSQMSSLERELETIHLENEGLKKKQVRLDEKLMEMQPLRSAGTHSPSSH-WDLQLLQQQACPMVPREQFLQLQQQLLQAEKRSQHLQEELDNRTSEPNTVQGSQEHLVNLMEERMIEVEQKLKLVKRLLQEKVNQLKEQLCKNSKTDAMVKDLYVENAQLLKALEMTEQRQKTAEKKNFLLEEKIASLSTIVRNLAPAPLTSMPPLRS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61043-3", "uniprot_id": "NIN_MOUSE", "id": "Q61043-3", "name": "Ninein", "aln": "---------------------------------------------------------------MDEVEEDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLCLEDVGP-VLQQTLLQDNLLGRVHFDQFKEALILILSRTLSS-----EEHFEESDCSPEAQPKYVRGGKRYGRRSLPEFQ-------------ESGEEIEEVTVLEPLEEEARSSPIPAGDCGEHWKTQR---SEEYEAEGQLRFWNPDDLNASHGGSCPPPDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPD--GTMSVEDFFYGLFKTGKSLTPSASTPYRQLKRHLSMQSFDESGRRTATSSAMTSTIG-FRVFSCLDDGMGQASVERILDTWQEEGIENSQEILKA--LDFSLDGNINLTELTLALENELLVTK-----NGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQEREQMLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSL--------------------------SEELDGHSGGIEPDQGPGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQ--------AAWTEEKVR----GLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRE-RATAAAMKQEQEILERTYKDRLNILSTERKQLLQDLKDLQNASESQHGLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERREMTGKLAALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAAS-LLMLQGGCQATAGEEAEGDGAMSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLEPGSVISSCLEEGTSEISGSSREQVEPIMKQ-------GPATKHFLSDLGDHEARDLASTGTSSVQRQECKTEASEASLDCFSELENSEDTRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLKMLERLPEASSRYKVLYEDAARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKVENEE---------------LRALVLRLQGKMEKVLGRAALQGDSYALWEAPSENLEVASDEKMLELRQTPKECTPKVVSMHHIIEECTQETQCCEQGSTKLLARIKAHEIAWFHRAIKTHPEKPSAQNRVIPEGSAALLGLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQ------EENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIK--NQQLDSENIELSQKNSQNKEELKTLNQRLAEMLCQRE-EPGACTSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLQTHVMEQENLLLKDELERLKQLHRCPDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSLLEHRI-------ATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAIDKDWVSETAPHLSGLRGQQRRLSWDKLDHLMNEEPQLLCQESKRLQTVVQNTQADLTHSREKVRQLESNLLPTKHQKQLNQPCTVKSTEQEKLTLKRECEQSQKEQSPTSRKVGQMGSLERGLETIHLENEGLKKK---------QMQPLRSTVTRSPSSH-WDLQLLQQQACPMVPREQFLQLQQQLLQAEKRSQHLQEELENRTSETNTPQGNQEHLVNLMEERMIEVEQKLKLVKRLLQEKVNQLKEQLCKNTKTDAVVKDLYVENAQLLKALEMTEQRQKTAEKRNFLLEEKIASLSTIVRNLAPAPLTSMPPLRS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4C6-1", "uniprot_id": "NIN_HUMAN", "id": "Q8N4C6-1", "name": "Ninein", "aln": "---------------------------------------------------------------MDEVEQDQHEARLKELFDSFDTTGTGSLGQEELTDLCHMLSLEEVAP-VLQQTLLQDNLLGRVHFDQFKEALILILSRTLSN-----EEHFQEPDCSLEAQPKYVRGGKRYGRRSLPEFQ-------------ESVEEFPEVTVIEPLDEEARPSHIPAGDCSEHWKTQR---SEEYEAEGQLRFWNPDDLNASQSGSSPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGEMLEEVFHNLDPD--GTMSVEDFFYGLFKNGKSLTPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIG-FRVFSCLDDGMGHASVERILDTWQEEGIENSQEILKA--LDFSLDGNINLTELTLALENELLVTK-----NSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENELLENAEKLAEYENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSP--------------------------SEEVEANSGGIEPEHGLGSEECNPLNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQS--------SAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKRE-KTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHKRELREREEVLCQAGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIHKATCETADRERAEMSTEISRLQSKIKEMQQATSPLSMLQSGCQVIGEEEVEGDGALSLLQQGEQLLEENGDVLLSLQRAHEQAVKENVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNTAEQTEQFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEGFSELENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKLKMLERIPEASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTETFLSLEKSYDEVKIENEG---------------LNVLVLRLQGKIEKLQESVVQRCD-CCLWEASLENLEIEPDGNILQLNQTLEECVPRVRSVHHVIEECKQENQYLEG-NTQLLEKVKAHEIAWLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQ------QENSILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIK--NQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAKSSLLEHRI-------ATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAELTHSREKVRQLESNLLP-KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKLDEQLMEMQHLRSTATPSPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERINQHLQEELENRTSETNTPQGNQEQLVTVMEERMIEVEQKLKLVKRLLQEKVNQLKEQVS-------------------LPGHLCSPTSHSSFN----------SSFTSLYCH----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A773-1", "uniprot_id": "A0A8I6A773_RAT", "id": "A0A8I6A773-1", "name": "Ninein-like protein", "aln": "---------------------------------------------------------------MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLP-ALLHILLGDGRLARVNFEEFKEGFVAVLSSATGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPE------LGDSATTTKCGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESPKEPQNELFEAQGQLRSWGCEVFGTPRKSCSPSFNTPENQVQGIWHELGVGSSGHLNEQELAVVCRSIGLHGLEKQELEELFSKLDRDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNGPWSHYQ--EESGCHTTTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQS--LDFNVDEKVNLLELTWALDNELLTVD-----GVIQQAALACYRQELNFHQGQVEQLVQERDKARQDLEKAEKRNLDFVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDVGRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLE---PQSMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRVRLPRSRQSPSGT-----------------------------PGTHRRWTPGRGPADNLFVGESIPVSLETEIKMQQMKENY----QELRMQLETKVNYYEKEIEVMKRNFEKDKKEMEQAFQLEVSVLEGQKADLETLYAKSQEVILGLKEQLQDAARSPEPAPAGLAPCCAQALCTLAQRLGVEMHLRHQDQLLQIRLSDTVTDSVLPR-----------------------------------VCSPKGSRKRTGHPNTKQTTERRVSGREAEEELNQKLSWLEAQHAACCESLSLQHQCEKDQLLQTHLQRVKDLAAQLDLEKGWREEREQEVLAHCRRQQLKLQAVMSEEQARICRSFTLEKEKLEQTYREQVEGLVQEADVLRALLKNGTTVVSDQQERIPGSMYPGPDSRQQPPT--------------------------------------------WQTVSPDGRTGAPAEWPGPGRADGRDLPGQLCSL--------------DAVPSPTPTLLSRRSSESLDVRDNHQGPLSAEEGAVPKEPEPSARTLTGQDQ----KLPLP--------IQPQMLEPWLGPAAVDR----------------------------KPDSVRVQGQASEGPTGDDKGVQETPLQLRGETARMRPSLPYSELPNPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAKVMSVMSESEMNDVKTKLLQLEDVVRALEK-ADSRES---------------------------YRAELQRLS------EENSVLKSDLGKIQLELGTSESRNEVQRQEIEVLKRDKEQACFDLEELSTQTQKYKDEMSQLNCR--ILQLEGD------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSGLHTQKEENHAAIQVLMKKLEEAECREKQQGDQIKHLKIELERVNEECQRLR----------------------------LSQAELTGSLEESQGQLHSVQLRLEAAQSQHDRIVQGLQEQMSQ-------------------------------------------------------------------------------------------------------------LVPGARVAELQHLLSLRE----------EEAER-LNAQQEEYKQQLKAREDQVEEAEARLHNVEWLLQEKVEELRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKMAPASLSV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ12-3", "uniprot_id": "NINL_MOUSE", "id": "Q6ZQ12-3", "name": "Ninein-like protein", "aln": "---------------------------------------------------------------MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLP-ALLHILLGDDRLARVNFEEFKEGFVAVLSSGSGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPE------LGDSATATKYGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESAKEPQNELFEAQGQLRSWGCEVFGTLRKSCSPSFSTPENLVQGIWHELGIGSSGHLNEQELAVVCRSIGLHSLEKQELEELFSKLDQDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNRLWSHYQ--EESGCHTTTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQS--LDFSVDEKVNLLELTWALDNELLTVD-----GVIQQAALACYRQELSYHQGQVDQLVQERDKARQDLEKAEKRNLDFVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDVGRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLE---PQSMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRLRLPRSRQSPAGT-----------------------------PGTHRRRIPGRGPADNLFVGESTPVSLETEIMVEQMKEHY----QELRMQLETKVNYYEKEIEVMKRNFEKDKKEMEQAFQLEVSVLEGQKADLEALYAKSQEVILGLKEQLQDAAQSPEPAPAGLAHCCAQALCTLAQRLEVEMHLRHQDQLLQIR-------------------------------------------------------------------------QEAEEELNQKLSWLEAQHAACCESLSLQHQCEKDQLLQTHLQRVKDLAAQLDLEKGRREEREQEVLAHCRRQQLKLQAVMSEEQARICRSFTLEKEKLEQTYREQVEGLVQEADVLRALLKNGTTVVSDQQERTPSSMSLGPDSRQQPTA--------------------------------------------RQAVSPDGRTGAPAEWPGPEKAEGRDFPGQLCSI--------------DAMPSPTPTLLSRRSSENLGVRDNHQRPLNAEEGAIPKEPEPSARTLTGQGQ----KLPLP--------VHPQMLEPSLGTTALDR----------------------------KAASVGVQGQASEGPVGDGEGVQEAWLQFRGEATRMRPSLPCSELPNPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EATVMPAMSESEMKDVKIKLLQLEDVVRALEK-ADSRES---------------------------YRAELQRLS------EENLVLKSDLGKIQLELETSESKNEVQRQEIEVLKRDKEQACCDLEELSTQTQKYKDEMSQLNCR--VLQLEGE------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSGLHTQKEENHGAIQVLMKKLEEAGCREEQQGDQIQNLKIELERVNEECQYLR----------------------------LSQAELTESLEESRSQLYSVQLRLEAAQSQHGRIVQRLQEQMSQ-------------------------------------------------------------------------------------------------------------LVPGARVAELQHLLNVKE----------EEARR-LSAQQEEYRQQLKAREDQVEDAEARLRNVEWLLQEKVEELRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKMAPASLSV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2I6-1", "uniprot_id": "NINL_HUMAN", "id": "Q9Y2I6-1", "name": "Ninein-like protein", "aln": "---------------------------------------------------------------MD-EEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLP-VLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPE------LCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQS--LDFSVDEKVNLLELTWALDNELMTVD-----SAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLE---PQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWS-----------------------------PDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHY----QDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLA--------LRHHSHLQQIR-------------------------------------------------------------------------REAEAELSGELSGLGALPARRDLTLELEEPP------QGPLPRGSQRSEQLELER-----------------ALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQ-ALPKDG-LVAGSGQEGTRGLLPLRPGCGERPLA--------------------------------------------WLAPG-DGRESEEAAGAGPRRRQAQDTEATQS-------------------PAPAPAPASHGPSE----RWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQ--------------AERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLREN---------------------------DRLEFHRLS------EENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVR--VLQLGQE------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQ----------------------------LPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVR---------------------------------------------------------------------------------------------------------------------LVPQDRVAELHRLLSLQG----------EQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G9G127-1", "uniprot_id": "NINL_DANRE", "id": "G9G127-1", "name": "Ninein-like protein", "aln": "---------------------------------------------------------------MDEDEQNRYVAQLKDEFDSCDTTGTGYLDKEELTALCHKLSLDAHLP-LLLDTLLGPQHYARVNFEEFKEGFVAVLSRSLDFSTSEEESSYLEPAVPEEVKPKYVKGTKRYGRRSRPDKTDLELTADSDSLPFGTDKVEANGVRRAKLRRSTSLESVESLKSDEDTGSNKESTHHYFVAQGQLKLWNQDGTGNCQRSSDNQQEVTDGQVRAVWEELGVGAAGSLNREELSLVCDHIGLKHLEAEELDALFRKLDKDQDGKVSLIEFQSGLFKPHDHASPLSTSTPARPKPLRTISKALEERVVRSTSPSLLSATVGQRLLTRLDDGSGCTSPEKVMALWTEEGIHNSRDILQTQTLDFSLEERLCLAELTLALDNELLVSG-----NGIHQAALVSYKNEINYLQVLADQACQERDKAKADLEQADRRNLQLVREVDDRHATMESLNESKIKDLEQEFRDKLTALRSESEYESEVLLEQVEKERERLRDELQLLRSQDISLQEDMCTTVNENRRLEEEVSALKEKLTEAESAISKLQNDLDRLLQDKYDGLDANGTGLLNQEEQFTEIFKEYEQQCRELQDRNDELCSELELLKSQGSGKRTRLSRSSLPANDWSNRRALTTESDSDDPEMKKGTSPQVRKKLQVTDKNVLGSLESLAPPVSIETELAMEKMKERYEQEVQDLKIQLETKVNFYERSMDLMRQNMEVERKDISQSFKMEISELEDLKARAEERAEQMRQTTERLEAELRGKTSGG--------------------------------------------------------------------------------------------------------------------------------------------------------AWGQEQERRIQRER------------------AELEQNYAREISNLVLRLTSEKDQLEAELKLRMDREVLLVRAQLDEVTSENCALKDRLAVLQQDVKSLEEDVNNKRK--------------------------------------------KLEEMEKGYMKNREDEERLRKENSK--------------------------------------------CREEVLDLSARNLQLSSENAELSSRLCTDQR---------------------------------------------------------------AVQTLTDRLAQVCQERDAAAVSSKQLQENLQQQENHGLRLQEQWRKEK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELLERELQTAKEALQHLTVVESALTSQTLKNKS---------------------------LEQDKESLL------KETAENDQKLKKLQEALRNSETQIEQLNAQILTMWQEKDVHVQEAAAHIKMLQQSQDKVQELEER--ISQLRKEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQVQHTHRLQEETAVSVLQNECKSLRVQNKELQNKVAQLQSRELELQRLTHECLTLR----------------------------NKQAELETAKQEANQQAMRAESTRSMVQAQHTREIQELKEQMGSGTQ------------------------------------------------------------------------------------------------EHASHLQTQLAEQQRRTQDFEDLLRSQA----------KQASVQMGLQQEQYEKLMASMQERMDEVEAKLKNTRVMLQEKVNQLKEQLAKNSKSDVLLKDLYVENSQLMKALQVTEQRQKSAEKKSFLLEEKVIALNKLLRKIAPASLTA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H2S6-1", "uniprot_id": "A0AC58H2S6_DANRE", "id": "A0AC58H2S6-1", "name": "", "aln": "MADSQYNLSCRSDLRACVCLCIFSTCAQARRCSSLSIIGFFCFLMDVSASLCFGQQVIGVIERLMDGARDQYEERLKEVFESFDGSGLGSLSPEELSDLCQALQLEENTLNTLLHTLLDDHITARVDFEQFKDALILVLSSTNTN----DEEECLEQPDSPEVQPRFVKGSKRYGRRSAPEFIP------------THTDSNIQADDEEEKDEDAQESDDRTVPRKRERWNADMSISEEFEAEGQLHLWNPDEPTTPR-GKALSLCDLEERLQNACLQLSLPVNGMATLSQLHALCQHIGIEVG-----EDLLQCADES---LMDVQEFISCVINHSKPPTPSASTPYRQLKRIHSTQFDESGRR----ISCALSSTIALRVFSDLDDGSGHAPVETLLNRWMEEGVDNSSEILQA--LDFNLEGKVNLSELTVALENELLSTK-----NSIHQAALLSFKAEIRHLLECVDLERREKERIRFDLDTAEKLKSELASEVDDHHAAIERNNELNLRRVEQEYKESMTALRTELSKEMELVQQQANQQREELEQEISKMRDDETFLREHLTLTIKENGRLESELIETTEKLVEAENQLNKVQKNLDGVLKEKFGDLDPDSAEFYQQEDRLRQLRRSYEEQCRELQDRIDELEAQLEEYQTSGHTPLRRPGLSLS--------------------------------DEMASKSLEPGFQEQQPLNMSLETEMLLEQHQREIEN----IRAMVDEEKRSAEEEKDLLSLNHQQELQVLRGEMERELERANKLEQEISVLQNLHQQELHSLTQEAQDAKTCAEQLQAKVQVLEEKQTAYEEQSNAHAEEMSLMELKHQEMLETSMQEQRERLEEEKEKRLTEQWKEQQKSYEEMLNAQLEEMQQRTEQECTELEKRLRDEWDQEKQELEESSREKLNSILEERERRLREEWEQERQELEEISKEALQAVLEERSERETRLRQQWDEERASMENKHHALLLQHLQEEREHFRTQQEETESIIFEHWARERAQLERQHKEALQACLEQERERLQVDREEQESRWQQVLIEEQSRVEEAHRGAMLELTAKHN-------------------EERERLSSLLEKLRTDIAEQRKELEKQFSQRLEEVEARFNSDQEAVSERFQADLQKLEQHYQSQITGLAQQHAANRALWEEESEITSKETEQQWKLLKEALDLEKEEFRLERQSLKLAHTQDIKALTDKNVQLQTELEVLASAAQTKEIELSRQLNELHKQVQERMEAKDLLLAQTENKVTELEKMLKQAVDDFIQEREELQKSLSALESRREVLSFQSMEIMGTIQEDEEILHQELKHERQALLSERDALALRVVQLEEIVLQLTGSTGEPCAEPLVESCTAESSIEGRESSAQLNQDTCPESIDKAIPVHIISLLVNQDDEEEAGVVDVVTDVSDPELHKHPELGVTNDRIDSNSCCDVKLVMAAVEPNNSRSETLDLEEEKETTNNLDVVVDGSEDAKSSELKNLKTNSRETQKNESLEMAEGGTEIEARICEEFAPYYIQESLGHHESPSTDDKPEKENHLENNISIANIESEIVTFANEICTLTTANEEDRVADLRDVCLQEILDLQDTVIQYSKTSETTTSLLPSPKLQDLEEENIINQIPKHLKEVVATFKDVQLANLKVCFEQSIQENLQLMEHNMKLEQRVKSLEDKMHIVQDFHMQQSSALEETTLLQVENSKLKVLLQEFVKQGKALQWDSDSSNMFKKSLHNSEMKEKIAAVAELEFFCIEFEKQNLHLRRALADLQSKSFRIHTQMQERRSEVCRLAKENFILRHKISTVREQDLRENQDDARLQHIKQGKRSVQALRRQLSEPRRLGQQLEEESFILQQNSDHVLRHALQEVIRQHDGSANGKNGLCDREEISSRTEKELLRSELNRCIEKIMSLDSSLQTVTQQNARLKSDLRITQQERDALKQEVMSLHKQLQSANEKLLEVSVVSAG----HQQGRRVWAELSGLMEAEHHSLKEENQQLKRQMNELSSELQTSKEQIRHLEALSAK-----------------------------------------------------------------------------QRGIVKNADQEKSALKREMEALHSQLLSTRNKAQLAAILPSSPLHLAGEQRG-SHNSDGPDFNIQEREAALLQMEERMREVEITLRNLKLLLQEKVSQLKEQLIRNSESDVLIKDLYVENAQLLKALEKTEQRQKVAEKKNFLLEEKISSLNKIVRDLGPSPLTPAPYHFTRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11929-1", "uniprot_id": "NINL_DROME", "id": "P11929-1", "name": "Ninein homolog", "aln": "----------------------------------------------------------------MEVSADPYEQKLYQMFRSCET-QCGLLDEKSLLKLCSLLELRDQGS-ALIASLGGSHQLG-VSFGQFKEALLNFLGSEFDG----------------NTSSGFIERS--------------------------------LVITDEPLNNTYIESPPESSDREVSPKLVVGTKKYGRRSRPQQGIYELSVTDSDNTDEDQLQQQQNQRSLNGCDELGVQVQRSSSQSDLPGSRRLRSVHTSGSKLKRCASLPARRK-----------MNSNTTGATTSPTAAAKLKQLSIQSQAQHSSSVESLDTVTPQQLETIS----------------VHSIMEAWELASIPNTRNLLHV--LGFDEEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYRQQHEENLKLRADNKAANQRVALLAVEVDERHASLEDNSKKQVQQLEQRHASMVREITLRMTNDRDHWTSMTG----KLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKT-------------------------------KAKKQEKQEKQEDQESAATATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSDASNSGDWLALNSELQR---SQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEQMQRAYEDCEDYWQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPIDE-----------------------------------------------------RDMLEQQYSELEAEAAQLRS--------------------------------------------------SSIQMLEEKAQEISSLQSEIEDLRQRLG------------------------------------------------------------------ESVEILTGACELTSESVAQLSAEAGKSPASSPISYLWLQSTIQEP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKSLADSKDEATASAIELLGGSPSHKTASRNNLT----------------------------TSETSIFS--------TTPFESSQSGPSPTNSGNSNAYGANPGPAPISKPKRSQSPQQAAASEGEIADCETSSTASGKS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FESNSKTSCLSHEKCSSPSALKEELKRLKFFELSLKEQIKDLSLQRDGLVMELQQLQ--------------------------------EARPVLEKAYARTTHPTLQQRLNQLELR-------------------------------------------------------------------------------------------------------------------------------------------------------NRHLQNVIKQQQHYTESLMQQSWRQHQVELNDLHSRIETQGVLLADQTQRLQSADILVKDLYVENSHLTATVQRLEQQRARVN-----LIHQQQQQQRLVGGGLPGMP----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* : : * : * *. :.* ** * * * * . * * :**:.:: .*. . :: . . : :. * : . . . : :*.: . ..* .:. . ::: . . . . . :: * .: * ::*: *.*. : .: * :** **::** . : :* *: .*. : : * . *:: :. *:*: *:::* .: ::: ::: . : : . : : . . *. :: . :: :: : .** .*: * :: : ::: .* . . :.: . : ** . :* : : : . . . : : . : : : ... : . . .. .. . . . .* . : . . . . : . : . :. ::: : : : * *: : . : . . . :: : : *. . :: : * .* : : : ", "identical_positions": 55, "similar_positions": 189, "identity": "2.39%" }, { "cls_id": "homologset.agr.FB:FBgn0000229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61831-1", "uniprot_id": "MK10_MOUSE", "id": "Q61831-1", "name": "Mitogen-activated protein kinase 10", "aln": "---MSLHFLYYCSEPTLDVKIAFCQGFDKHVDVSSIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRSYIDQWNKVIEQLGTPCPEFMKKLQPT-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHN-KLKASQARDLLSKMLVIDPVKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK-------TKNGVVKSQPSPSGAAVNSSESLPPSS-AVNDISSMSTDQTLASDTDSSLEASAGPLGCCR---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49187-1", "uniprot_id": "MK10_RAT", "id": "P49187-1", "name": "Mitogen-activated protein kinase 10", "aln": "---MSLHFLYYCSEPTLDVKIAFCQGFDKHVDVSSVVKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHN-KLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK-------TKNGVVKGQPSPSGAAVNSSESLPPSS-SVNDISSMSTDQTLASDTDSSLEASAGPLGCCR---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53779-1", "uniprot_id": "MK10_HUMAN", "id": "P53779-1", "name": "Mitogen-activated protein kinase 10", "aln": "---MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHN-KLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK-------TKNGVVKGQPSPSGAAVNSSESLPPSS-SVNDISSMSTDQTLASDTDSSLEASAGPLGCCR---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YV43-1", "uniprot_id": "A0A8M6YV43_DANRE", "id": "A0A8M6YV43-1", "name": "Stress-activated protein kinase JNK", "aln": "MVFMNRRFLYNCSAPVLDVKIAFCQGFGKQVDVSYIAQHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPEFMKKLQPT-VRNYVENRPKYAGLTFPKLFPDCLFPADSEHN-KLKASQARDLLSKMLIIDPAKRISVDEALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEER-------TKNGVVKGQPSPSGAAVNSSESLPPSS-SVNDISSMSTDQTLASDTDSSLETSAGPLGCCR---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45983-1", "uniprot_id": "MK08_HUMAN", "id": "P45983-1", "name": "Mitogen-activated protein kinase 8", "aln": "-----------------------------------------MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER-------TKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49185-1", "uniprot_id": "MK08_RAT", "id": "P49185-1", "name": "Mitogen-activated protein kinase 8", "aln": "-----------------------------------------MSRSKRDNNFYSVEIADSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCLKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER-------TKNGVIRGQPSPLGAAVINGSQHPVSSPSVNDMSSMSTDPTLASD-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Y86-1", "uniprot_id": "MK08_MOUSE", "id": "Q91Y86-1", "name": "Mitogen-activated protein kinase 8", "aln": "-----------------------------------------MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER-------TKNGVIRGQPSPLAQVQQ----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45984-1", "uniprot_id": "MK09_HUMAN", "id": "P45984-1", "name": "Mitogen-activated protein kinase 9", "aln": "-----------------------------------------MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPT-VRNYVENRPKYPGIKFEELFPDWIFPSESERD-KIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER-------SKNGVVKDQPS---DAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49186-1", "uniprot_id": "MK09_RAT", "id": "P49186-1", "name": "Mitogen-activated protein kinase 9", "aln": "-----------------------------------------MSDSKSDGQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPT-VRNYVENRPKYPGIKFEELFPDWIFPSESERD-KIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER-------SKNG-VKDQPS---DAAVSSKATPSQSSSINDISSMSTEHTLASDTDSSLDASTGPLEGCR---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTU6-1", "uniprot_id": "MK09_MOUSE", "id": "Q9WTU6-1", "name": "Mitogen-activated protein kinase 9", "aln": "-----------------------------------------MSDSKSDGQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPT-VRNYVENRPKYPGIKFEELFPDWIFPSESERD-KIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEER-------SKNG-VKDQPS---DAAVSSKATPSQSSSINDISSMSTEHTLASDTDSSLDASTGPLEGCR---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DGD9-1", "uniprot_id": "MK08_DANRE", "id": "Q9DGD9-1", "name": "Mitogen-activated protein kinase 8", "aln": "-----------------------------------------MNRNKREKEYYSIDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMG-YQANVDVWSIGCIMAEMVRGSVLFPGTDHIDQWNKVIEQLGTPSQEFMMKLNQS-VRTYVENRPRYAGYSFEKLFPDVLFPADSDHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEVEAPPPAITDKQLDEREHSVEEWKELIYKEVLEWEER-------TKNGVIRGQPASLAQVQQ----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P92208-1", "uniprot_id": "JNK_DROME", "id": "P92208-1", "name": "Stress-activated protein kinase JNK", "aln": "-------------------------------------------MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD-LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPT-VRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAH-------NTNNRTR---------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32485-1", "uniprot_id": "HOG1_YEAST", "id": "P32485-1", "name": "Mitogen-activated protein kinase HOG1", "aln": "--------------------------------------------MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSP-----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERF-------------KTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDP-TDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNGAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. :: .: * : .** :*.*:* ** *:**:. * : **:**: :**.. . ***:***: *:* :.*:*:* * : * . ::*:*:* ** .::* :::: *::: :.*:***:* *:*::*:**:**********::: :* *** ****** . ** ** ********::* * :**:** ***:.*:: :* * .::.*:. : : **:* ..: : . .:* . *: * . * : .:* :**.***::*. :**:. :** * * ::*. :. . * .:: : .:: *: ::*.*::: . . ", "identical_positions": 118, "similar_positions": 122, "identity": "23.6%" }, { "cls_id": "homologset.agr.FB:FBgn0000239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3THK7-1", "uniprot_id": "GUAA_MOUSE", "id": "Q3THK7-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "MALCNGDSKPENAGGDLKDGSHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPILGICYGMQMMNKVFGGTVHKKSVREDGVFNIS-MDNTCSLFRGLQKEEIVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLYDIAGCSGNFTVQNRELECIREIKEKVG-TSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNGFMRKRESQSVEEALKK-LGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMSLK--PEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGFAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPG-NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V7C6-1", "uniprot_id": "GUAA_RAT", "id": "Q4V7C6-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "MALCNGDSKPENAGGDLKDGCHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNIS-MDNTCSLFRGLQKEEIVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLYDIAGCSGNFTVQNRELECIREIKEKVG-TSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNGFMRKRESQSVEEALKK-LGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMSLK--PEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMEITSQHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPG-NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49915-1", "uniprot_id": "GUAA_HUMAN", "id": "P49915-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNIS-VDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVG-TSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKK-LGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLK--PEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPG-NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIE7-1", "uniprot_id": "Q9VIE7_DROME", "id": "Q9VIE7-1", "name": "GMP synthase (glutamine-hydrolyzing)", "aln": "---MNSNIFLGTAENGLR------HDKIVILDAGAQYGKVIDRKVRELFVETDILPLDTPAATIRNNGYRGIIISGGPNSVYAEDAPSYDPDLFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIE-IETSCPLFSRLSRTQSVLLTHGDSVERVGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQMLSNFLYEICELTPNFTMGSRKEECIRYIREKVG-NNKVLLLVSGGVDSSVCAALLRRALYPHQIIAVHVDNGFMRKKESEKVERSLRD-IGIDLIVRKEGYTFLKGTTQVKRPGQYSVVET---PMLCQTYNPEEKRKIIGDIFVKVTNDVVAELKLK--PEEVMLAQGTLRPDLIESASSMVSTNAETIKTHHNDTDLIRELRNAGRVVEPLCDFHKDEVRDLGNDLGLPQELVERQPFPGPGLAIRVLCAEEAYMEKDYSETQVIIRVIVDYKNKLQKNHALINRVTAATSEAEQKDLMRISSNSQIQATLLPIRSVGVQGDKRSYSYVVGLSTSQEPNWQDLLFLAKIIPRILHNVNRVCYIFGEPVQYLVTDITHTTLNTVVLSQLRQADDIANEIIMQAGLYRKISQMPVVLIPVHFDRDPINRTPSCRRSVVLRPFITNDFMTGVPAEPGSVQMPLQVLNQIVRDISKLDGISRVLYDLTAKPPGTTEWE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38625-1", "uniprot_id": "GUAA_YEAST", "id": "P38625-1", "name": "GMP synthase [glutamine-hydrolyzing]", "aln": "---MAAGEQVSNMF-----------DTILVLDFGSQYSHLITRRLREFNIYAEMLPCTQKISELG-WTPKGVILSGGPYSVYAEDAPHVDHAIFDLNVPILGICYGMQELAWINGKQVGRGDKREYGPATLKVIDDSNSLFKGMN-DSTVWMSHGDKLHGLPTGYKTIATSDNSPYCGIVHETKPIYGIQFHPEVTHSTQGKTLLKNFAVDLCHAKQNWTMENFIDTEINRIRKLVGPTAEVIGAVSGGVDSTVASKLMTEAIG-DRFHAILVDNGVLRLNEAANVKKTLVEGLGINLMVVDASEEFLS--------------------KLKGVTDPEKKRKIIGNTFIHVFEREAEKIKPKDGKEIQFLLQGTLYPDVIESISFKGP--SQTIKTHHNVGGLLENMK--LKLIEPLRELFKDEVRHLGELLGIPHDLVWRHPFPGPGIAIRVLG-------------------------EVTKEQVEIARKADNIYIEEIKKAGLYNQISQAFACLLPVKSVGVMGDQRTYDQVIALRAIETTDFMTADWFP------------------------------------------------------------------------FEHSFLKKVAS-------------------------------------RIVNEVDGVARVTYDITSKPPATVEWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . :::** *:**.::* *::**: : ::::* : :.:*:**** ******** * :* : *:******** : * * : . ** * .:. :: : .** :. . * ::***.:. : . * . * * .* :* :** ****** : :** :*.** ::. . .:*: . *. *:: ** . :*: :******:*.: *: .*: .:. *: :***.:* .*: .*:.:* . :**:: * . . * . * . .**:******: *::: : ::. * * :* **** **:*** * . :: ****** *:.::: :::*** ::.***** **. *.:*.:** *:******:****: .: * :. : * : :. .. . * ***:::*** ** *:*. * .: : : .:: ::. *::. ::: .* :.:: *::*: **:*:***.*.***", "identical_positions": 173, "similar_positions": 175, "identity": "24.71%" }, { "cls_id": "homologset.agr.FB:FBgn0000244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8I3-1", "uniprot_id": "TENS4_RAT", "id": "Q4V8I3-1", "name": "Tensin-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSLLTGGHVVSLTPHEESRMALHPTPSHDLPALCPYYTTESWGTQPLMDPTLCKGSSNR-----LQQAQQAEARAQCLLQCPGEQASGASQDLDSCIDFSLEALNKMILELDP----------------------------------------------------------------------------------------------------------TFQLLPSGIAGPQAEPTNSVASRTKKEEPDALDIKYIEVTSTR-------SRCLDSPQRCSSP-------CVTPPFG---------------SPRSGGLFLSRDIPRETRSSSNESLIFSGNQGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSPHTPSSLSNSIPCRESRAS------------------------------------------------------------------------------------GSPLATPPGWEKGLR---------------------------------------------------------------------------------------APQWGSRVSTLSASPVSDISYVFGSNQS----------------------------------------------------------------------------------------------------------------LPHSSLSSYPPSSRSLGSPASSSS------------------SLHSLDRGSQCVRSSDAQVPSNPIVGMGQPQ------------------AVPSTPVAKEQASSCPPSVTNSMADIPIVLINGNPEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPPAQQTPRYQDS----------------VQSRATSPSHLCQATKSHSK----------------------------TLPDVPLTSPSHLCQATKSHSKTLPDVPLTASPESP----------------------------AKDMQPTMKFVMDTSKYWFKPSITREQAINLLRTEKPGTFVIRDSSSYRGSFGLALKVQETPASAPNR---PGEDSTDFIRHFLVESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQKELGG--AEPASDSPTHGQTSCLKISAG---------CHTLYLTSVSVETLSGALAVQKAISVMLERDVLPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLIALRFCGMDPEQRKWQ--KYCKPSRIFGFVAKSQTEPQENACHLFAEYDAAQPASQVISLVTALLKDTERV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ33-1", "uniprot_id": "TENS4_MOUSE", "id": "Q8BZ33-1", "name": "Tensin-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSLLAGGHMVSLTPCEESRMALHPTPSPGLPALCPYYTTESWGTQPLMAPTLRKGSSDR-----LQQAQQAEARAHCLLQGPGEQASGASQDLESCIDFSLEALNQMILEIDP----------------------------------------------------------------------------------------------------------TFQLLPSGTAGPQAESTNSIMSRNKKEEPEALDIKYIEVTSTR-------SRYLDGPQRCSSP-------CATPPFG---------------SPRSGSLFLSRDIPRETRSSSNESLIFSGNQGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPSPLTPSSLSNAIPCRESRTS------------------------------------------------------------------------------------GSPLATPPGWEKGLR---------------------------------------------------------------------------------------APQRGSRVSILSASPVSDVSYVFGSNQS----------------------------------------------------------------------------------------------------------------LPHSSLSSYPSSSRSLGSPASSSS------------------SLHSLDRGSQCGRPSDAQAPSNPILGMGQPQ------------------AVQSTPVAKEQASSCPASVTNSMADIPIVLINGSPEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPPAQRTPGHQDS----------------VQSRVTSPSHLCQAIKSP--------------------------------------------------SKTLPDVPLPASPDGP----------------------------AKDMQPTMKFVMDTSKYWFKPSITREQAINLLRTEKPGAFVIRDSSSYRGSFGLALKVQETSASAPNR---PGEDSSDLIRHFLIESSAKGVHLKGADEEPYFGSLSSFVCQHSIMALALPCKLTIPQKELGG--AEPASDSPTHGQTSCLKISAG---------CHTLYLSSVSVETLSGALAVQKAISVTLERDVLPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLSALRFCGMDPEQRKWQ--KYCKPSRIFGFVAKSQTEPQENVCHLFAEYDAVQPASQVISLVTALLQDTERM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZW8-1", "uniprot_id": "TENS4_HUMAN", "id": "Q8IZW8-1", "name": "Tensin-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCMGPPGR-----LQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDP----------------------------------------------------------------------------------------------------------TFQLLPPGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSAR-------SRCHDGPQHCSSP-------SVTPPFG---------------SLRSGGLLLSRDVPRETRSSS-ESLIFSGNQGRGHQRPL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPSEGLSPRPPNSPSISIPCMGSKASSPHGL-------------------------------------------------------------------------------GSPLVASPRLEKRLGG-------------------------------------------------------------------------------------LAPQRGSRISVLSASPVSDVSYMFGSSQS----------------------------------------------------------------------------------------------------------------LLHSSNSSHQSSSRSLESPANSSS------------------SLHSLGSVSLCTRPSDFQAPRNPTLTMGQPR------------------TPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSPPQRTPGHQNS----------------VQPGAASPSNPCPATRSN--------------------------------------------------SQTLSDAPFTTCPEGP----------------------------ARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSR---PGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGG--ADGASDS-TDSPASCQKKSAG---------CHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRKWQ--KYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A656-1", "uniprot_id": "A0A8I6A656_RAT", "id": "A0A8I6A656-1", "name": "Tensin-1", "aln": "----------MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERSEPGGAASIQRRRLLLQPEDLEAPKTHHFKVKAF-KKVKPCGVCRQAITREGCICKVCSFSCHRKCQAKVAAPCVPPSSHELVPIATESVPKNVVDVGEGDCRGGSTPKNLEEAGSMRVSPSIQPQPQPQPQPISLSRNLSVSRAMEDSCELDLVYITERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFNGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNG------SSGPITTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSG----AAIAPAALSPQEKKE----------LDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVSSPGRHIVPAQVHVNGGALASERETDILDDELPI-QDGQSGGSMGTLSSLDGVTNTSEGGYPETLSPLTNGLDKPYPTEPILNGGGYPYESANRVVPVHSSHSAP-IRPSYSAQEGLGGYQREGPHPAWSKQVTSAHRGYDPSGLFRSQSFPDVEPQLPQAPARGGSSREAVQRGLNSWQQQQQQQQQQQQQQQQQQQQQPHPPPRQQERSPLQSLACSKPSPHLSAETPIPALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAP-LHKSQSVPGAWPGASPLSSQPLLGSSCQSHPLTQSRSGYIPSGDTLGAPELLS--------SGRSYSPYDYQLHPAASNQSFRPKSPASS------TFLPSPHSSAGPQEP----PASLPGLIAEPQLPLKETTSDTS-----RTPEEEPLNLEGLVAHRVAVYNARLQSLRQSSSSRPSLHRLRSASLSRVQARERQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEG---------------------TSPSSPPPSVARSPPGLAKTPLSALGLKPHNPADILLHPTG---------------------EPRSYVESVARTAVAGPRAQDVEPKSFSAPATHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSAGSSDQGPRTPIQPMLDSSIRS--GSLGQPSPAALS-YQSSSPVPVGGSSYSSPDYSLQPFSSSPESQGQPHFSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAINPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPTSATVAPGSPSLGRHPVGSHQVPGLHSGVVTTPGSPSLGRHPGAHQGNLVSSLHGNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSS----------------ASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSP--TPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMASPSGSSTVSFSHTLPDFSKYS-----MPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQ-GKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSS--GPANSTTDLLKQGA---------ACNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q0S6-1", "uniprot_id": "TENS1_MOUSE", "id": "E9Q0S6-1", "name": "Tensin-1", "aln": "----------MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERCEPGGAAPDPRRRLLLQPEDLEAPKTHHFKVKAF-KKVKPCGICRQAITREGCVCKVCSFSCHRKCQAKVAAPCVPPSSHELVPITTETVPKNVVDVGEGDCRVGSSPKNLEEGGSMRVSPSIQPQPQSQP--TSLSRNTSVSRAMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYLHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNG------SSGPVTTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSG----ATTAPAALSPQEKKE----------LDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVPSPGRHIVPAQVHVNGGALASERETDILDDELPI-QDGQSGGSMGTLSSLDGVTNTSESGYPETLSPLTNGLDKPYSTEPVLNGGGYPYEAANRVIPVHSSHSAP-IRPSYSAQEGLAGYQREGPHPAWSQQVTSAHCGCDPSGLFRSQSFPDVEPQLPQAPTRGGSSREAVQRGLNSWQQQQ-----------------PHPPPRQQERSPLQSLARSKPSPQLSAETPVAALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAP-LHKSQSVPGAWPGASPLSSQPLLGSSRQSHPLTQSRSGYIPSGHSLGTPELVS--------SGRPYSPYDYQLHPAGSNQSFHPKSPASS------TFLPSPHSSAGPQEP----PASLPGLIAQPQLPPKETTSDPS-----RTPEEEPLNLEGLVAHRVAG----------------------------VQARERQPAEPPGPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEG---------------------TSPSSPPHSVARSPPGLAKTPLSALGLKPHNPADILLHPTGVARRLIQPEEDEGEEVTKPPEEPRSYVESVARTAVAGPRAQDVEPKSFSAPAAHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSVVSSDQGPRTPFQPMLDSSIRS--GSLGQPSPAALS-YQSSSPVPVGGSSYNSPDYSLQPFSSSPESQGQPQYSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAVNPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPASAATTPGSPSLGRHPVGSHQVPGLHSSVVTTPGSPSLGRHPGAHQGNLASSLHSNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHAAYGGYSTPEDRRPTLSRQSS----------------ASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSP--TPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMAS--GSSTVSFSHTLPDFSKYS-----MPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQ-GKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSS--GPANSTTDLLKQGA---------ACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBL0-3", "uniprot_id": "TENS1_HUMAN", "id": "Q9HBL0-3", "name": "Tensin-1", "aln": "--------------MTWICLS-------------------------------------CMLWPEDLEAPKTHRFKVKTF-KKVKPCGICRQVITQEGCTCKVCSFSCHRKCQAKVAAPCVPPSNHELVPITTENAPKNVVDKGEGASRGGNTRKSLEDNGSTRVTPSVQPHLQPIR-------NMSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHG------STGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPG----ASSATAALSPQEKRE----------LDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGALASERETDILDDELPN-QDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAP-MRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQ------------PRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAP-LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSL---PAFLPTTHSPPGPQQP----PASLPGLTAQPLLSPKEATSDPS-----RTPEEEPLNLEGLVAHRVAG----------------------------VQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEG---------------------TSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTG---------------------EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRS--GSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSS----------------ASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSP--TPALPEKRRMSVGDRAGSLPNYATINGKVSS-PVASGMSSPSGGSTVSFSHTLPDFSKYS-----MPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQ-NKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSS--GPANSTADLLKQGA---------ACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PT37-1", "uniprot_id": "A0A8M9PT37_DANRE", "id": "A0A8M9PT37-1", "name": "", "aln": "----------MGCTVSFICCEDDFLQMPLDQHVE-----------------KKKEEKRLLFKPEEFEAVHSHTFRLKTF-KKGKHCGVCKQTVNNEGLICRVCRLACHRKCEVKVSSSCVPVANYELAPSN------------------ELPLKHIETTGSTKSSKSMESRRRPSR-------SLSLIQAMEENYEVDLVYITERIISVTFPSNAEEPSYSANIKEVANMLRSKHGDNYLLFNLSEKRLDISKLNPKVLDFGWPDHHAPALDKICSICKAMDTWMNAGSHNVVVIHNKGNRGRTGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVLPVGQPSQRRYVQYFSGLLSGHIKINNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTSICITIEPGLLLKGDILLKCYHKRFRSPCRDVIFRVQFHTCAVHDLGIVFGKDELDETFKDDRFPEYGKVEFVFSFGPEKIQGMDHLENGPSVSVDYNTQDALIRWDSYENFNQRCEDSMEDVI-HTEGPLDGSLYAKVRKKESLEGGVTANGLPAAADHTLPAVDHTLPPVDHALSVSSDSGNSTASIKTDRTDEASHQPALVSQPSSQPLSPEEKQE----------LDQLLSGL------EAPMHRTGYQSSPGGGGGGGGGGVLHLVPAQVHVNG-HSNIDRETDILDDDLPISQEGNSVDSLGTLSSFEGRATP---------------ADLYYQSETVINGQDMPYLEK----IVHEKMLEPRVHSSSSVQEHLGGPS--GYANQNGNIYRSQSLGATPN---------TDQKYMPKAPARTTSSRDAVQR-LNVWQQYG------------------VPEVPVTDGVTFNPVLQS------------HSLPEFPQMASQQEIEQSIEALNMLMLDLDPALTQVPKSHSAPSGESGVVTTQPSFSQTQARPSYQADTAIHDRGAASSMGFPLTFQQVTG----------EPSQPTMKQQKPTTTSQHVEFASEAGGQAPMSQSTVPSSTFGVLQLKPLNIYPSSTTSQSPEPQETQRSYSSSSSPLPKESEPEDSSYKLEGLVAHRVAEYTARIRCINDSQSAPEFGHRRRSLSFSGLPSGEMSPDEAAVPGRCRTRSEGLSQDESP----TRGSSVRSPIRCISPELANTIALNPGGRPKERHMHSYREAFEEMDGGPVSPPPIVGGEVLPQTPAFPVSPQTPYFNMCRSPPGLAKTPLSFLGLKPHNPAEILLNQTGSE--------------SEDEEEPRSYVESVAK-AAAVPASPTYDSDSLARPAGPSHAYNAPLSSSSP---IQNPDPVESTLADSGVGMNSLSQAAVDIFHFQPSEIPYQPPPPPYPTSMLGSYISPSPAEAMQNNTTTIQPLSGSPGTRHHTILSDMASVPNFQHRLANQDG---PILGRQQAPANGHVPGIAGSPVQGR----HTMVSQGTQSSPILSRQYPVTQGIQSSPILSRQPMGQAVQSSPVLNRQAS--LNQANQSSPVLSRQQSITLPNQGSPVLSRQSSLSHP----SQGSPVLGRHP----SLTQGSPSLDRHPMYSGYTTPEERHGALSRQSS----------------SSGYQPPSTPSFPVSPAGY-----------IEGAGFRQGSPAFQPQLPEKRRMSSSDRTNGGLSYGTLNGKMSS-PVSSGGSTP----SVHFFHTLPDFSKLN-----MCDGSPETRMNVKFVQDTSKFWYKPDISRDQAINMLKDQDPGAFVIRDSHSFRGAYGLAMKVASPPPTTQPT-KKAGDVTNELVRHFLIETSPKGVRLKGCPNEPYFGCLSALVYQHSITPLALPCKLVIPTRDPLEESPEIA--TPTNPAADMLKQGAGQKSSADGHACNVLYINSVDMESLTGPQAIAKAISETMNASPAPSATIVHFKVSAQGITLTDNQRKLFFRRHYPIGTVTFCDIDPQERKWNKPEGGT-AKFFGFVARKQGSTTDNVSHLFAEMDPDQPATAIVNFVSKVMISS-QKR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6A502-1", "uniprot_id": "A0A8I6A502_RAT", "id": "A0A8I6A502-1", "name": "", "aln": "MLRPGDPQGSGARAVRGDCPSRLEGALPRARAASQEDGPAREQLGAQLRFGHRPAGLRCGFAQPEEFTTCPHSFKKKDF-KKHRVCGVCRQTIDGQGIACRTCKYSCHKKCEAQVVTTCS--------------------------------------AQVHLDQAPEGSTPSAPLRCDKPSRPVVLSSAMEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAVKMNASPLFLHFVILHGAPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMS------ADGEVLHTQGPVDGSLYAKVRKKSASDS-------GIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERQTPG------ARRGLSPQEKAE----------LDQLLSGFG--------LEDSANSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPH-HDLHSVDSLGTLSSSEGPQST----------------------------------------------------------------------------------------------------HLGPFACLKSSQNSLLSDGFGNG-------------------------------------------------------------VAEDHNGVLSPDLGLGVDSVYERERMCGGREQKQLQPLSRKPSAPTPTQAYGQSNYSTQTWVRQQQMVTAHQYSFASDGEAR-------------------------------------------HGSRSAVDSAGLAQPSPHIPVTPTHGTSSRVAVQRGISNGPN------PPD----------------------------------------------AQQLCPSKALQPRFPDDRVMNGVVHQELNPGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLSALGLSANGSMY---------------------PDGVGSGLRCGGRL-DPVDGPGRSPGRQG-------DDPVG----------------------GRLRKLSIGQYDNDAGSQVTFSKCGWGKAGADSAPSLGSFS-----------SPADIKETVITAYPPDLDVIDGRIPNSKESPICLTPAFP----------VSPETPYVKTSPRYPPFSPPEPQLSIPASLHKG-REPRGCTEIISHTVGMSESPLGSKPTLLRADMPATPN--------FQQVFAASCTVSSNGPGQRRESPPSAERQWAESSPKSTLTLLGNNRPSESPLGTHEFCSSGKNSPGLPCFQSSELQASFHSHELSMSESQDAMPPAGSQTFLGFNTVTTVTSGLPPSEDAGTLLVNSHGPSPVPGTPLTTTG----------------AADNGFLSHNFLTVSPGASS-----HHSPGLQNQGISLPGQ---PPLPEKKRTSEGDRS---LGSVSPSSSGFSSPHSGSTMS------IPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGA---------ACNVWYLNSVEMESLTGHQAVQKALNMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWI-KDG-PSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SSZ5-1", "uniprot_id": "TENS3_MOUSE", "id": "Q5SSZ5-1", "name": "Tensin-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKCKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNNDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKISALMEPSQKRYVQFLSGLLSGAMKMNTSPLFLHFVIMHGVPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMS------ADGEVLHTQGPVDGSLYAKVRKKSASDT-------GIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERLTPG------ARRGLSPQEKAE----------LDQLLSGFG--------LEDSASSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPH-HDLHSVDSLGTLSSSEGPQST----------------------------------------------------------------------------------------------------HLGPFTCLKSSQNSLLSDGFGNG-------------------------------------------------------------VAEDHNGVLSPDLGLGVDTLYDRERMCGGREQKPLQPLLRKPSAPTPVQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEAR-------------------------------------------LGSRSTVDNTGLAQPPPHIPVTPNRGASSRVAVQRGISNGPN------PPD----------------------------------------------TQQLCPGKALQPRFQDDRVTNG-VHQEPNTGSSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLNALGISA---VC---------------------PDGVGSGLRCSGRL-DSVDGPGRSPGRQG-------DDPIG----------------------GRLRKLSIGQYDNDAASQVTFSKCGWGKAGVDPAPSLGSFS-----------SPEDIKETVITAYPSDLNMIDGRIPNSKESSMCLTPSFP----------VSPETPYVKTSPRYPPFSPPEPQLSSPASLHKG-REPRGCPEIISHTVGMSESPVGPKPTMLRADMPATPN--------FQQVFASSCTVSSNGPGQRRESPPSAERQWVESSPKSTLTLLGNSHPSESPLGTHEFCSSGKDSPGLPCFQSSELQASFHSHELSMSEPQGALPPAGSQTFLGFNTVTTATSVLPPGEDAGTLLVNSHGTSPAPGTPLLTTG----------------AADNGFLPHNFLTVSPGASS-----HHSPGLQNQNVSLPGQ---PPLPEKKRASEGDRS---LGSVSPSSSGFSSPHSGSTMS------IPFPNVLPDFCKPSEVASPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGA---------ACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWI-KDG-PSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CZ2-1", "uniprot_id": "TENS3_HUMAN", "id": "Q68CZ2-1", "name": "Tensin-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSATPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLS------ADGEVLHTQGPVDGSLYAKVRKKSSSDP-------GIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPG------TRRGLSAQEKAE----------LDQLLSGFG--------LEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPH-HDLHSVDSLGTLSSSEGPQSA----------------------------------------------------------------------------------------------------HLGPFTCHKSSQNSLLSDGFGSN-------------------------------------------------------------VGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEAR-------------------------------------------LVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPH------PPD----------------------------------------------TQQPSPSKAFKPRFPGDQVVNG-AGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVS---------------------PDSVGGGLRASSRLPDTGEGPSRATGRQGS----SAEQPLG----------------------GRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFP-----------SPADVKETMTPGYPQDLDIIDGRILSSKES-MCSTPAFP----------VSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPS--------FQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPL-SAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAP-VGSGLPPEEDLGALLANSHGASPTPSIPLTATG----------------AADNGFLSHNFLTVAPGHSS-----HHSPGLQGQGVTLPGQ---PPLPEKKRASEGDRS---LGSVSPSSSGFSSPHSGSTIS------IPFPNVLPDFSKASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGA---------ACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKWI-KDG-PSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8N8-1", "uniprot_id": "A0AB13A8N8_DANRE", "id": "A0AB13A8N8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEGSEFDLNYITERVIGITFHQTCTEQTYQHNLSRITQLLQSKHADRYMVINLSEHSDDLCRMNHRVVDLGWPESHAPSLHLLCSVCKNMDSWLSAHPDNVLLLHCKGSKDRVGVVISSYIQLSSVSTSEEHALDLYSMKRFCSDQMVNLLTPSQKRYVQVFGRLLKHQIPLNHSPLFIHHVTIHPIPDFHP-TVCQLFIRVNQGTQTAYTSGLHQVDVGLMDRVCFVLDPPQMIKGDIMIVCYHKNVSTRTQETLFRAQFHTAALSAKQFALQKEDLDLANKDPRFPENCVVEVLFSEVADK--------------------DPTLASDCDQWRS------SLAVVIEND--LPDSLQTQWDLS------------------ENLPATAKPHEG--TRSLSSDSGLSSSSQWTGG----QASG------LLISYSPEENNQ----------LNTVTPGLR--------MEEEQSSP---GTLRRDPTTSQSVLDYSGHLNGDSMFTERETDIIDDDE------------DDITSPNDAIAA----------------------------------------------------------------------------------------------------VSDSLSFKETS-------GLSSG-------------------------------------------------------------QSSDYQNEASP------------AKFRGDVN-----------TSNSVIDTSVPAGYQTRIWVKQQQ---STSYAHTP---------------------------------------------------------------------------TDRLEVKQELRSDAS------KPS----------------------------------------------TPDNCLPEAPSETDKDD--------------------VMALDQSIEQLNQLILDLDPEFKPIPTQP-------------------------------------QSHMTRSASL--YTNGKTQSMGKAK-------SHLSG----------------------WRQKQLS----DVSEYSVLQNTSGDQTQNTQRFDFSTPSLR-----------GLYHTDAVDFGDLPPEVDRPLWVGLNQAPP----TPAFP----------VTPPTPYVKSGNDFT-NSRPGSQTSRHYMSSPVWQESRGFTDSMTHTSMSSDG------EIFHSDVTGSPAS-------CQRMFGSLHSISTPSPLVNADSPTPAH-SWLEG---------GSSTP-------------------LSHYTPQ------PSPPLTLSAP------------------------------------NSHSSP--RRAPRSLSS----------------ALDMGSLESSLLEAVEG-------------LEALGLDVAQP---PLLPLKRRGTDG------------SENMLSFPLSRSTVS------TSYASHNTSPSR----STPSPDFMASKPENVKFVQDTSKFWYKPDISREQAISVLKDKEPGSFIIRDSHSFRGAYGLAMKVATPPPTVLQTSRKVGDLSNELVRHFLIECTPKGVRLKGCPNEPYFGSLTALVCQHSITPLALPCRLIIPSRDPLEEFNESPTQTSTNSAAELLKQGA---------ACNVWFLGSVDLESLTGVQGVQKATTVTFNKDPPPTSTVVHFKVSAQGITLTDNQRKLFFRRHYAVSTVIFCALDPQDRKWK-RDGCTAAKIFGFIARKSGSSTENVCHLFAEHDPEQPASAIVNFVSKVMIGSQKNK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63HR2-1", "uniprot_id": "TENS2_HUMAN", "id": "Q63HR2-1", "name": "Tensin-2", "aln": "---------------------------------------MKSSGPVER-LLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNT----------------------APVRRIEHLGSTKSLNHSKQRSTLPRSFSLD----PLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQR----------------PPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPP----------PTAAERQELDRLLGGCG--------------------VASGGRGAGRETAILDDEEQPT------VGGGPHLGVYPG-----------------------HRPGLS-------------------------------------------------------------------------------------------------------------RHCSCRQGYREPCGVP-----------------------------------------------------------------NGGYYRPEGTLERRR-----LAYGGYEG-SPQGYAEASMEKRRLCR----SLSEGLYPYPPEMGKPATGDFGYRAPGY--------------------------------------------------REVVILEDPGLPALYPCPACEEKLALPTAALYGLR--------------------------------------------------------LEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHP---GYP----------------------ALVTYSYGGAVPSYCPAYG--RVPHSCGSPGEGRGYPS-----------------------PGAHSPRAGS-ISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHL------ASAGPLASAESLEPVSWREGPSGHSTLPRSPR--------------------DAPCSASSELSGPSTPLHTSSPVQGKESTRRQD-------TRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSG-------------PEPLAPSPVSPTFPPS-------SPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQ-GPRGPPDSPDGSPLTPVPSQMPWLVASPEP-----------------------PQSSPTP------------------------AFPLAAS-----------------------------YDTNGLSQPPLPEKRHLP----GPGQQPGPWGPEQASSPARGISHHVT----FAPLLSDNVPQTP--------EPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPP--SAQPW-KGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAA---------CSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDG-TTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGB6-1", "uniprot_id": "TENS2_MOUSE", "id": "Q8CGB6-1", "name": "Tensin-2", "aln": "---------------------------------------MKSSGPVER-LLRALGRRDSSRATSRPRKAEPHSFREKVFRKKTPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRST----------------------APVRRIEHLGSTKSLNHSKQRSTLPRSFSLD----PLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYVSYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYRIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGSRLTFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGALAHTRGPLDGSPYAQVQR----------------VPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPP----------PTAAERQELDRLLGGCG--------------------VASAGRGAGRETAILDDEEQPS------VGGGLHLGMYSG-----------------------HRPGLS-------------------------------------------------------------------------------------------------------------RRCSCRQGFREPCGVP-----------------------------------------------------------------NGSYYRPEGTLERRR-----PPYGGYEG-HPQGYAEASVEKRRLCR----SLSEGPYPYAPELGKPANGDFGYRPAGY--------------------------------------------------REVVILEDPGVPALCSCPACEEKLALPTAALYGLR--------------------------------------------------------LEREAAEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPMPDYGCLKPPKVGEEGHEGCSYAVCSEGRYGHS---GYP----------------------ALVTYGYGGAVPSYCPAYG--RAPHSCGSPSEGRGYPS-----------------------PGAHSPRAGS-VSPGSPPYLQPRKLGYEISAEDGRDKYPLSGHL------ASTGPLASTESPEP-SWRDGSSGHSTLPRSPR--------------------DPQCSASSELSGPSTPLHTSSPVQGKESNRRQDT------TRSPSLAPTQRLSPGEALPSVVQGVAEKTPELLTSSR-------------PEQLDPSPFSQTSAPG-------SPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQ-GPRGTSDSPDGSPLTPVPTQMPWLVGSPEP-----------------------PQSSPTP------------------------AFPLATS-----------------------------YDANGPIQPPLPEKRHLP----GSGQQP--------SPPARSTNQHVT----FASPLPD-VTQPP--------EHPLQENQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPP--SAQPW-KGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAA---------CSVLYLTSVETESLTGPQAVAKASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDG-ATSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PKG9-1", "uniprot_id": "A0A8M9PKG9_DANRE", "id": "A0A8M9PKG9-1", "name": "", "aln": "---------------------------MGCIFSKQQWEKETSSQPSDPPKTRDHAEDAEILSLTELEKMGSHCFKERNFKKKL-HCAVCRQTLDSLGMYCRECKTAVHKKCEEKVSVPCEAVS------------------------------------------DPPPLQNQMNVPQSKASMETVMENLMGSHYDFDLTYITERIISVLYQSDLDEQSYSANLKVVAPMLKSKHQDKFLLINLSEKRHDICRLNPKVEEFGWPDLHAPPLDKICAVCKTMENWLNSDPNNVVVLHCKGNKGKTGVIVAAYMHYSKISAGADQALSTVAMRKFCEDKISSFILPSQNRYIYYFAGLLSGSIKMNSSPLFLHQIHVPVSPNYQSGGGYAPFLKIYQSLQLVYSSGKYDIQGPNSKTLCVNIEPALLLKGDILVKCYHRLSDVCKRECVFRVQFHTCSVHGSQLAFGKGELDHACTDDRFPSDATVELLFSTGPQRRGGDVP-GNEPGVSADYGSTDPVVRWDSYENFNLHHEDSVED-ISHTRGPLDGSLYAQVKKRRAQGS------SPSRCPTSIKPSTYSPTHSS-----STSPIHLS-VQPLSLSKDTSRSS----------AAPESLTPLPREKR-----------------------EKDENRERHRETAILDDGECSP------LRPDRPVQSCYG--------------HPFSHTHSYCGPDLTSP----------------------------------------------------------------------------------------------------HAIAVQPKHRTLPCNRTTPLSVR-----------------------------------------------------------------DLCVSQPDLLWERGR----CLHHPCPES-VRHLYSYPPQETHTHSPIPQTSHSHTLPPQTRAYFSGEACPLFHCSALP--------------------------------------------------QGHNHIPPSLSPNQSLLTSPYR--ELRYSTTSPTS--------------------------------------------------------CSCRDCLRLREDVALHS----LRGRELETLP----WSREAEFGIRREAPVHW-RDGRAESHWEGVQEAEYWRRKIAMSP----------------------VMLSYGHCQAVPKQEQAVYVTDPQPEHG-LSPFPSPQS-----------------------SGYHSPHPPCPCSP-QP-FRDSPGYASISHSQNSSPIALTPSPK------RANHNRAS-AEENQHGPNEEYTKILSDDKSP----------------------ATFSPPTQNSGP-VKAGEMVQIKSPEDVNLPV------------SLITNISSASGAEDKTTITDCTSNSLLISSQP-------------SSKNMESVQVQTLNPR--------PLSVPESEQDKGER---PGSCYTSTTTSTSPQ-----PPLCSSERSSASEFSSFNLNGERQSVTPLTDCNE------------------ESNSDPD----GFITP----------------SFPIASHGYPLLTVP-----------HVPYTGYTEITIPTNLAQPPLPEKQRSSPLHNTSDYTPTSLIKSAGKPSVSSAQVHVS----FSTTTNEVPPKSTCRIPLSSGVD-EPESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTE-PGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQDLQSGTNTSTAADLLKQGAA---------CNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVSTQGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRWVDADN-TSCKMFGFVARRSGALGN-VCHLFAELDPEQPATAIVNFINKVMLGPQQLRK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PL00-1", "uniprot_id": "A0A8M9PL00_DANRE", "id": "A0A8M9PL00-1", "name": "", "aln": "---------------------------MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKR-QCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGT----------------------SSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLED-IAHTRGPVDGSLYAQVKKRRAAAG------CSSLPSTNGSPARSSEERPSQLLSVSTDSGHSS-VPPDRLDEPTRPAP----------PTQQEREELERLLGGI---------------------EGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNG----------------------------------------------------------------------------------------------------HTGALSPGMSSVIGLCQHHSTHP-----------------------------------------------------------------HQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHP----HSLSPRLLCRPDEYISYPHHHHNHSHHPK--------------------------------------------------PSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLR--------------------------------------------------------LDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYG-----------------PHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSS-----------------------SGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASC------PGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCT------PSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQ--PSGQHHVT----FSPSVGELAVPIG---QVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSS-KGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAA---------CNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDS-TTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC3-1", "uniprot_id": "TENSN_DROME", "id": "Q9VHC3-1", "name": "Tensin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTPYEESAAAADHKYQYQYTAANNNNNYYKNYNVNGNGQANGNGNLSG-------------------------IGNGNGIGNGNGYGIPYHARENSLPFSYGIAKTSTPLRKTPTPTRVDSFLDFDFGPTNTNVNSNSSSNNGGTGDMIKPPTRLTSPLLVRKTLGNAVSPTSSTNTNTIANTYHYTSSSATPTPVRDNFEQLLRERREKVYNEYRNLDRESSGERARVAPAPPQRQYYPSDGYGIG-------------------------------------------------------------------------------------------------------------LKNDSNGTLYRKSPSSNGKSTKYNYDFEFNLNLDDVRPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTPYTTRNIHFEDLRLDQDVPDG---------------------------------------------------------------------------------VVNRRTMERNYHTINS---------------------------------------------------------------------------------------LETTHKRQQLEPLEQLGAVYGQNHMEETLTRTRR-----------------------------------------------------------------------------------------------------------DLSASTSTSKSTSPLPAIGVPAIAP---------------ASPIYATSTKRVSNPNTNGQQQMTPSPTSRPE---------------------TPAFPVTPRTPFGASSSSSASLAPTTQLPPES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYQTGPRRGVPPALQP--------------------------------------------------------------------------------------------------------------------------------LEVSADSVQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDSYGLVVRVSQPPPG-----------SQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQLALPCLLRLPDRDIVP-----PVRATTPAQQHLLAHGAA---------TNVLWLYSCDTESLTGNEAIRKAIRQMYGQQPLPQPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKKTIFAFVARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTLPTEKLRNYVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : . . . . . :*. .:*::*:*. ::*::** * .* *::*** :::.::**.::* .. :::****:* **::**. *. * .*:::* :**: ::*** * :* :: .* . :: * . *:*:* .: :: . * .: *****: ******* *: ***:** : .. ** :: * .*.*:*: : .*:*.: . *** :: : . : ", "identical_positions": 71, "similar_positions": 92, "identity": "3.45%" }, { "cls_id": "homologset.agr.FB:FBgn0000250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63746-1", "uniprot_id": "IKBA_RAT", "id": "Q63746-1", "name": "NF-kappa-B inhibitor alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFQPAGHGQDWAMEGPRDGLKKERLVDDRHDSGLDSMK-------------------------------------------------------------------------DEDYEQMVKELREIRLQPQEAPLAAEPWKQQ-------------------------------------------------LTEDGDSFLHLAIIHEEKTLTMEVIGQVKG--DLAFLNFQNNLQQTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAVLTQTCT-----------------------------------------PQHLHSVLQATNYNGHTCLHLASIHGYLGIVEHLVTLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADV--NRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQTLPE-------------SEDEESY-----DTES---EFTEDELPYDDCVFGGQRLTL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1E3-1", "uniprot_id": "IKBA_MOUSE", "id": "Q9Z1E3-1", "name": "NF-kappa-B inhibitor alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFQPAGHGQDWAMEGPRDGLKKERLVDDRHDSGLDSMK-------------------------------------------------------------------------DEEYEQMVKELREIRLQPQEAPLAAEPWKQQ-------------------------------------------------LTEDGDSFLHLAIIHEEKPLTMEVIGQVKG--DLAFLNFQNNLQQTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAVLTQTCT-----------------------------------------PQHLHSVLQATNYNGHTCLHLASIHGYLAIVEHLVTLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADV--NRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPE-------------SEDEESY-----DTES---EFTEDELPYDDCVFGGQRLTL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25963-1", "uniprot_id": "IKBA_HUMAN", "id": "P25963-1", "name": "NF-kappa-B inhibitor alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMK-------------------------------------------------------------------------DEEYEQMVKELQEIRLEPQEVPRGSEPWKQQ-------------------------------------------------LTEDGDSFLHLAIIHEEKALTMEVIRQVKG--DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCT-----------------------------------------TPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADV--NRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPE-------------SEDEESY-----DTESEFTEFTEDELPYDDCVFGGQRLTL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JIA3-1", "uniprot_id": "IKBB_RAT", "id": "Q9JIA3-1", "name": "NF-kappa-B inhibitor beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVACLGKTADADEWCDSGLGSLG-------------------------------------------------------------------------PDAAAPGGPGLVAELSPELSWAP---LVFGY-------------------------------------------------VTEDGDTALHLAVIHQHEPFLDFLLGFSAG---TEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVTERGGHTALHLACRVRAHTCAYVLLQPRPSHPRDASDTYLTQSQDHTPDTSHAPVATDPQPNPGNEEELRDEDWRLQLEAENYDGHTPLHVAVIHKDAEMVQLLRDAGADLNKPEPTCGRTPLHLAVEGQAAGVLALLLKAGADP--TARMYGGRTPLGSALLRPNPVLARLLRAHGAPEPEDKDDKLSPCSNSSSDSDSDNRDEG-----DEYDDIVVHSRRSQNQPPPSPAAKPLPDDPNPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60778-1", "uniprot_id": "IKBB_MOUSE", "id": "Q60778-1", "name": "NF-kappa-B inhibitor beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVACLGKTADADEWCDSGLGSLG-------------------------------------------------------------------------PDAAAPGGPGLGAELGPELSWAP---LVFGY-------------------------------------------------VTEDGDTALHLAVIHQHEPFLDFLLGFSAG---TEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVAERGGHTALHLACRVRAHTCACVLLQPRPSHPRDASDTYLTQSQDCTPDTSHAPAAVDSQPNPENEEEPRDEDWRLQLEAENYDGHTPLHVAVIHKDAEMVRLLRDAGADLNKPEPTCGRTPLHLAVEAQAASVLELLLKAGADP--TARMYGGRTPLGSALLRPNPILARLLRAHGAPEPEDEDDKLSPCSSSGSDSDSDNRDEG-----DEYDDIVVHSGRSQNRQPPSPASKPLPDDPNPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15653-1", "uniprot_id": "IKBB_HUMAN", "id": "Q15653-1", "name": "NF-kappa-B inhibitor beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVACLGKAADADEWCDSGLGSLG-------------------------------------------------------------------------PDAAAPGGPGLGAELGPGLSWAP---LVFGY-------------------------------------------------VTEDGDTALHLAVIHQHEPFLDFLLGFSAG---TEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANP--AARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSS---SDSDSGDEG-----DEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54910-1", "uniprot_id": "IKBE_MOUSE", "id": "O54910-1", "name": "NF-kappa-B inhibitor epsilon", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDARKGPDEADDSQCDSGIESLRSLRSLPEPTAAPGSGSSQSGCPQPWRHAPET---------HKEPE-KEDADGERADSTYASSSLTESFPLLERPEAKDPSPPAPGSPLPPAGVLSPQQLEALTY-------------------------------------------------ISEDGDTLLHLAVIHEAPSVLFCCLAFLP----QEVLDIQNNLYQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACRRQNLACACCLLEEQP-------------------------------------EPGRQLSHPLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADIDVQEGTSGKTALHLAVETQERSLVQFLLQAGARV--DARMLNGCTPLHLAAGRGLNSISSTLCEAGADSLLLN---------------VEDETPQ-----DLAEDLLSYLPFDDLKIS----GKPLLCTD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P780-1", "uniprot_id": "Q6P780_RAT", "id": "Q6P780-1", "name": "NF-kappa-B inhibitor epsilon", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDARKGPDEADDSQCDSGIESLRSLRSLPDPAAAPVSGSSHSGCPQPWSHAPKT---------DKEPEGKEDADGERADSTYASSSLTESLPLLERPEAKDPNPPTPSSPVSPAGVLSPQQLEALTY-------------------------------------------------ISEDGDTLLHLAVIHEAPSVLFCCLAFLP----QEVLDIQNNLYQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACQRQNLACACCLLEEQP-------------------------------------EPGRQPSHPLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADIDAQEGTSGKTALHLAVETQERSLVQFLLQAGARV--DARMLNGCTPLHLAAGRGLNSISSTLCEAGADSLLLN---------------VEDETPQ-----DLAEDLLSYLPFDDLKIS----GKPLLCTD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03017-1", "uniprot_id": "CACT_DROME", "id": "Q03017-1", "name": "NF-kappa-B inhibitor cactus", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSPTKAAEAATKATATSDCSCSAASVEQRAPSNAANPSSSLATSGKIGGKTQD---------------------QTAAINKQKEFAVPNETSDSGFISGPQSSQIFSEEIVPDSEEQDKDQQESAPQKEQPVVLDSGIIDEEEDQEEQEKEEEHQDTTTATADSMRLKHSADTG-IPQWTVESHLVSRGEQLNNLGQSSSTQITGRSKVQSSTASTANANPSGSGATSSAPPSSINIMNAWEQFYQ-------------------------------------------------QNDDGDTPLHLACISGSVDVVAALIRMAPH---PCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFG-----------------ATEIHEAHRQYGHRSNDKAVSSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDS------------DYDSSDIE-----DLDDTKMYDRFGDPRYFVSYNGGNPMTVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q63369-1", "uniprot_id": "NFKB1_RAT", "id": "Q63369-1", "name": "Nuclear factor NF-kappa-B p105 subunit", "aln": "MADDDPFGTGQMFHLNTALTHSIFNAELYSTDIPLSTADGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGSTGSPGPGYGFPHYGFPAYGGIAFHPGATKSNTGITHGTINTKFKNEPRDCAKSDDREILNPPEKETQGEGPSLFMASTKTEAIAPASTMEDKEEDVGFQDNLFLEKALQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGSISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLHLAAKEGHDKILGVLLKNSK--------------------------------------------AALLINHPNGEGLNAIHIAVMSNSLSCLQLLVAAGAEVNAQEQKSGRTALHLAVEYDNISLAGCLLLEGDAL-VDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEKAGEDEGVVPGTTPLDMAANWQVFDILNGKPYEPVFTSDDILPQGDIKQLTEDTRLQLCKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELVEALRQMGYTEAIEVIQAAFRTPETTASSPVTTAQAHLLPLSSSSTRQHIDELRDNDSVCDSGVETSFRKLSFSESLTGDGPLLSLNKMPHNYGQDGPIEGKI", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** ::**: **** * . : ::::*:: **.****. : . * *. : : *.: **::. * : :: * :* :*:* :. * **::: * *::.**:*:: .: ** * :. : : * :. * . .. : ", "identical_positions": 39, "similar_positions": 53, "identity": "3.83%" }, { "cls_id": "homologset.agr.FB:FBgn0000251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47902-1", "uniprot_id": "CDX1_HUMAN", "id": "P47902-1", "name": "Homeobox protein CDX-1", "aln": "---------------------------------------------------MYVGYVLDKDSPVYPG-------------PARPAS-LGLGPQAYGPPAPPPAPPQYPDFSSY---------SHVEPAPAPPTAWGAPFPAP-KDDWAAA--YGPGPAAPAA-----------SPASLAFGPPPDFSP------------VPAPPGPGPGLLAQP-LGGPGTPS-------SPGAQRPTP------------------YEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKK--------------KQQ-----QQQ---PPQPPMAHDITATPAGPSLGGLCPSNTSLLATSSPMP--------VKEEFLP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18111-1", "uniprot_id": "CDX1_MOUSE", "id": "P18111-1", "name": "Homeobox protein CDX-1", "aln": "---------------------------------------------------MYVGYVLDKDSPVYPG-------------PARPSS-LGLGPPTYAPPGPAPAPPQYPDFAGY---------THVEPAPAPPPTWAAPFPAP-KDDWAAA--YGPGPTASAA-----------SPAPLAFGPPPDFSP------------VPAPPGPGPGILAQS-LGAPGAPS-------SPGAPRRTP------------------YEWMRRSVAAAGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKK--------------KQQ-----QQQPLPPTQLPLPLDGTPTPSGPPLGSLCPTNAGLLGTPSPVP--------VKEEFLP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05095-1", "uniprot_id": "CDX1_RAT", "id": "Q05095-1", "name": "Homeobox protein CDX-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKK--------------KQQQQQQQQQQPMPPTQLPLPLDGTPTPSG-HPGSLCPTNAGLLGTPSPVP--------VKEEFLP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESV7-1", "uniprot_id": "Q9ESV7_RAT", "id": "Q9ESV7-1", "name": "", "aln": "---------------------------------------------------MYVSYLLDKDVSMYPS-------------SVRHSGGLNLAPQNFVSP------PQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPTAYGAPLREDWNG---YAPGG-AAAANAVAHGLNGGSPAAAMGYSSPAEYHAHHHPHH--HPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPSGQRRNL------------------CEWMRKPAQPSLG-SQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKK--------------KLQQQQQ-QQP-PAP-PPPQPSQPQSGALRSVPEPLSPVTSLQGSVPGSVPGVLGPAGGVLNSTVTQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43241-1", "uniprot_id": "CDX2_MOUSE", "id": "P43241-1", "name": "Homeobox protein CDX-2", "aln": "---------------------------------------------------MYVSYLLDKDVSMYPS-------------SVRHSGGLNLAPQNFVSP------PQYPDYGGYHVAAAAAATANLDSAQSPGPSWPTAYGAPLREDWNG---YAPGG-AAAANAVAHGLNGGSPAAAMGYSSPAEYHAHHHPHH--HPHHPAASPSCASGLLQTLNLGPPGPAATAAAEQLSPSGQRRNL------------------CEWMRKPAQQSLG-SQVKTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQVKIWFQNRRAKERKIKKK--------------QQQQQQQ-QQQ-QPPQPPPQPSQPQPGALRSVPEPLSPVTSLQGSVPGSVPGVLGPAGGVLNSTVTQ------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99626-1", "uniprot_id": "CDX2_HUMAN", "id": "Q99626-1", "name": "Homeobox protein CDX-2", "aln": "---------------------------------------------------MYVSYLLDKDVSMYPS-------------SVRHSGGLNLAPQNFVSP------PQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNG---YAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHH--HPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNL------------------CEWMRKPAQQSLG-SQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKK--------------KLQQQQQ-QQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVPGSVPGVLGPTGGVLNPTVTQ------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZF67-1", "uniprot_id": "D3ZF67_RAT", "id": "D3ZF67-1", "name": "", "aln": "---------------------------------------------------MYGSCLLEKEAGMYPGTLRNPGGGSTAGVGTSGGSGSPLPASNFTAA------PVYPHYMGYP------HMSNMDPHGPSLGAWSSPYSPP-REDWST---YP-GPSSTMGTVPMND----MTSSSPAFGSP-DYSTLGPTGGAGGASNGGSLPDAASESLVSIDSGTSGGAT-------SPSRSRHSP------------------YAWMRKTVQ-----VTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERKMIKK--------------KIS-----QFE---NSGGSVQSDSGSISPGELPNAFFTT-------PSAVRGFQPIE--IQQVIISE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07424-1", "uniprot_id": "CDX4_MOUSE", "id": "Q07424-1", "name": "Homeobox protein CDX-4", "aln": "---------------------------------------------------MYGSCLLEKEAGMYPGTLRSPGGSSTAGVGTSGGSGSPLPASNFTAA------PVYPHYVGYP------HMSNMDPHGPSLGAWSSPYSPP-REDWST---YP-GPPSTMGTVPMND----MTS--PVFGSP-DYSTLGPTS---GASNGGSLPDAASESLVSLDSGTSG-AT-------SPSRSRHSP------------------YAWMRKTVQ-----VTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERKMIKK--------------KIS-----QFE---NTGGSVQSDSGSISPGELPNAFFTT-------PSAVRGFQPIE--IQQVIVSE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14627-1", "uniprot_id": "CDX4_HUMAN", "id": "O14627-1", "name": "Homeobox protein CDX-4", "aln": "---------------------------------------------------MYGSCLLEKEAGMYPGTLMSPGGDGTAGTGGTGGGGSPMPASNFAAA------PAFSHYMGYP------HMPSMDPHWPSLGVWGSPYSPP-REDWSV---YP-GPSSTMGTVPVND----VTSSPAAFCST-DYSNLGPVG---GGTSGSSLPGQAGGSLVPTDAGAAK-AS-------SPSRSRHSP------------------YAWMRKTVQ-----VTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKK--------------KIS-----QFE---NSGGSVQSDSDSISPGELPNTFFTT-------PSAVRGFQPIE--IQQVIVSE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8KBT9-1", "uniprot_id": "A8KBT9_DANRE", "id": "A8KBT9-1", "name": "", "aln": "---------------------------------------------------MYVGYLLEKEASMYH-------------QGAVRRSGISLPPQNFVST------PQYSDFTGYH------HVPNMETHAQSAGAWGAPYGAP-REDWGA---YSLGPPNSIS-APMSN----SSPGPVSYCSP-DYNTMHGPG-------SAVLPPPPENIPVAQLS---------------PERERRNS------------------YQWMSKTVQSS---STGKTRTKEKYRVVYTDHQRLELEKEFHFNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERKLIKK--------------KLG-----QSD---GSGGSVHSDPGSVSPLPVPGSLSPSDIHGSLYPAQMNALPSMRN-IQQVTVTQ------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09085-1", "uniprot_id": "CAD_DROME", "id": "P09085-1", "name": "Homeotic protein caudal", "aln": "MVSHYYNTLPYTQKHSAANLAYASAAGQPWNWTPNYHHTPPNHQFLGDVDSSHAAHHAAAAHQMYYN------SHHMFHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQP-QPGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAAVGTLSM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:********.********: .*****:**:*** .*.*:***************** ** . : . . . : : : . ", "identical_positions": 52, "similar_positions": 18, "identity": "11.98%" }, { "cls_id": "homologset.agr.FB:FBgn0000253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DP31-1", "uniprot_id": "CALM3_RAT", "id": "P0DP31-1", "name": "Calmodulin-3", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DP25-1", "uniprot_id": "CALM3_HUMAN", "id": "P0DP25-1", "name": "Calmodulin-3", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DP29-1", "uniprot_id": "CALM1_RAT", "id": "P0DP29-1", "name": "Calmodulin-1", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DP23-1", "uniprot_id": "CALM1_HUMAN", "id": "P0DP23-1", "name": "Calmodulin-1", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DP26-1", "uniprot_id": "CALM1_MOUSE", "id": "P0DP26-1", "name": "Calmodulin-1", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DP27-1", "uniprot_id": "CALM2_MOUSE", "id": "P0DP27-1", "name": "Calmodulin-2", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DP28-1", "uniprot_id": "CALM3_MOUSE", "id": "P0DP28-1", "name": "Calmodulin-3", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DP24-1", "uniprot_id": "CALM2_HUMAN", "id": "P0DP24-1", "name": "Calmodulin-2", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DP30-1", "uniprot_id": "CALM2_RAT", "id": "P0DP30-1", "name": "Calmodulin-2", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62152-1", "uniprot_id": "CALM_DROME", "id": "P62152-1", "name": "Calmodulin", "aln": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06787-1", "uniprot_id": "CALM_YEAST", "id": "P06787-1", "name": "Calmodulin", "aln": "MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREVS-DGSGEINIQQFAALLSK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.:*************:*****.:*:*::.**.******* .*:***::*::**:*.*** *:*.***::*:*::*..***:*: ***:****:*:* ******:**:*.:****** ***:*:**.. **.*::* ::*. ::: ", "identical_positions": 88, "similar_positions": 50, "identity": "59.06%" }, { "cls_id": "homologset.agr.FB:FBgn0000256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AUE2-1", "uniprot_id": "A0A8I6AUE2_RAT", "id": "A0A8I6AUE2-1", "name": "Formin-2", "aln": "MGNQDGKLKRSAGDASHEGGGGGAEDAAGPRDAETTKKASGSKKALGKHGKGGGGSG---ETSKKKSKSDSRASVFSNLRIRKNLGKGKGAGDSREDVLDSQALPIGELDSAHSIVTKTPDLSLSAEETGLSDTECADPFEVIHPGGSRPAEAGVGIQAIAEDLETAAGAQDG--QRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQQKLLLQD---------SEEPAAPPTAISPQPGAFLGLDQFLLGTS-----SEAKKDTVQAPPVRPDLPETTKS--LVPEHPPSSGSHLASETPGYATAHSAVTDTLSSPAFTFPEVPEAGPGEGAAGVPPAGTGDTDEECEEDAFEDAPRGSPGEEWAPEV-EEASQRLEEEPEEGMRGPIIPAVASLPGSPAPSPRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKKRPDPSVSRSPRTALASAATPAKKHRLEGGLVGGLSRSADWTEELGARTPGAGGSVHLLGRGATADDSGGGSPVLAAKAPGAPATADGFQNVFTGRTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAGSSSAPFDQDQLYTWAAVSQPTHSMDYSEGQFPRREPSTWRPSKLPDEEPSPKDIDTAYLEEPQSSILESPKKCSNGVQQEVFDVKSEGQATVIQQLEQTIEDLRTKIAALEKQYPSLDLEGPR----LENGLTASADVSLDALGLHGKVAHPPRTLEAKSIQTSPTEEDRILTLPPPKAPPEGLPGPPAAESGESALLTSSSGPQTKFCSEISLIVSPRRISVQLDAQPAMQSTSQLPPPPSLLGADSQGQP-SQP-------SLHPELETSHEHSVFSSFENSCNIPPAPPLPCTESSSFMPGLGTAIPPPPCLSDITVPALPSPTAPALQLTNLQGPQMLPTPPQ-----------------------------------------------------PPSLSGPGVPPPP--------PPPPLPGVGIPPPPPLPGMGIPPPPPLPGMGIPPPPPLPGVEIPPPPPLPGGGIPPPPPLPGGGIPPPPPLPGGGIPP----------PPPPLPGVGIPPPPPLPGVGIPPPPPLPGVVIPPPPPPP---------------------------------------PPPLPGVGIPPPPPLPGMGIPPPPPLPGVGIPPPPALPGVAIPPPPPLPGMGVPPPAP--------------PPPGAGIPPPPQLPGSGLPLSSQDGSSTLPAAPQGCGFLFPPLPTGLFGLGMNQDRVARKQPIEPCRPMKPLYWTRIQLHSKRDSSPSLIWEKIEEP-SIDCHEFEELFSKTAVKERKKPISDTIS-KTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFD------------------------------------EDAGKEQCVFPLSEPQELFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSEEHKQPFKENMEQFISQAKIDQETQETALTETHKCFLETTAYYFMKPKLGEK---EVSPNVFFSVWHEFSSDFKDSWKKENKLILQERVKEAEEVCRQKKG-KSLYKVKPRHDSGIKAKISMKT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL04-1", "uniprot_id": "FMN2_MOUSE", "id": "Q9JL04-1", "name": "Formin-2", "aln": "MGNQDGKLKRSAGDASHEGGG--AEDAAGPRDAEITKKASGSKKALGKHGKGGGGSG---ETSKKKSKSDSRASVFSNLRIRKNLTKGKGACDSREDVLDSQALPIGELDSAHSIVTKTPDLSLSAEETGLSDTECADPFEVIHPGASRPAEAGVGIQATAEDLETAAGAQDG--QRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQ--KLLLQD---------SEEPAAPPTAISPQPGAFLGLDQFLLGPR-----SEAEKDTVQALPVRPDLPETTKS--LVPEHPPSSGSHLTSETPGYATAPSAVTDSLSSPAFTF---PEAGPGEGAAGVPVAGTGDTDEECEEDAFEDAPRGSPGEEWVPEV-EEASQRLEKEPEEGMRESITSAVVSLPGSPAPSPRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKKRPDPSVSRSSRTALASAAAPAKKHRLEGGLTGGLSRSADWTEELGVRTPGAGGSVHLLGRGATADDSGGGSPVLAAKAPGAPATADGFQNVFTGRTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAGSSSAPFDQDQLYTWAAVSQPTHSMDYSEGQFPRREPSMWPSSKLPEEEPSPKDVDT----EPKSSILESPKKCSNGVQQEVFDVKSEGQATVIQQLEQTIEDLRTKIAELEKQYPALDLEGPRGLSGLENGLTASADVSLDALVLHGKVAQPPRTLEAKSIQTSPTEEGRILTLPPPKAPPEGLLGSPAAASGESALLTSPSGPQTKFCSEISLIVSPRRISVQLDAQ-QIQSASQLPPPPPLLGSDSQGQP-SQP-------SLHTESETSHEHSVSSSFGNNCNVPPAPPLPCTESSSFMPGLGMAIPPPPCLSDITVPALPSPTAPALQFSNLQGPEMLPAPPQ-----------------------------------------------------PPPLPGLGVPPPP--------PAPPLPGMGIPPPPPLPGMGIPPPPPLPGMGISPLPPLPGMGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPP----------PPP-LPGVGIPPPPPLPGVGIPPPPPLPGVGIPPP--------------------------------------------PPLPGVGIPPPPPLPGVGIPPPPPLPGSGIPPPPALPGVAIPPPPPLPGMGVPPPAP--------------PPPGAGIPPPPLLPGSGPPHSSQVGSSTLPAAPQGCGFLFPPLPTGLFGLGMNQDRVARKQLIEPCRPMKPLYWTRIQLHSKRDSSPSLIWEKIEEP-SIDCHEFEELFSKTAVKERKKPISDTIS-KTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFD------------------------------------EDAGKEQCVFPLAEPQELFQASQMKFEDFQKDLRKLKKDLKACEAEAGKVYQVSSAEHMQPFKENMEQFISQAKIDQESQEAALTETHKCFLETTAYYFMKPKLGEK---EVSPNVFFSVWHEFSSDFKDAWKKENKLILQERVKEAEEVCRQKKG-KSLYKVKPRHDSGIKAKISMKT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ56-1", "uniprot_id": "FMN2_HUMAN", "id": "Q9NZ56-1", "name": "Formin-2", "aln": "MGNQDGKLKRSAGDALHEGGGG-AEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNLRIRKNLSKGKGAGGSREDVLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDG--QRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPF---PEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGRTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAET----ESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPP----VDGLPGRPPCPPG------AESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPP-----HSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIP--QPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP-TPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEP-SIDCHEFEELFSKTAVKERKKPISDTIS-KTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFD------------------------------------EDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEK---EVSPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEEVCRQKKG-KSLYKIKPRHDSGIKAKISMKT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A4Y9-1", "uniprot_id": "D4A4Y9_RAT", "id": "D4A4Y9-1", "name": "", "aln": "MEGTHCTLQLHN--------------------------------------------------------PIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDITSLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDNLLRSDNILGISMGNQEGKLQELSVSLAPTDDYFQSAGNWSRELPVSSLIRRSSQENKKPRRSGRRR----------ESPEELGQKRTRRKGRGCQESALQMGKD-----QVCSSSSFSP-RARPNLRLLEERGNLVPQGTLTSSSLRRRESCPANILRTPDAD--------------------------LGLGNSGKTSEDTEL-EGPLSPDSSPTEVGDTDVGGQLKSSPKQEPPQPNLSENHEKLPGAERWGSGTRKSKSLERTCSKKPVSKVVAKVKEP-------SAPVQRIVRAHHDVKGRVAFCPESQTEFIPKADFLTLPGDEAETLSSRTLGEEQQGIKSLRSSATERASITKEPASTEGAVNKVLRKVIESEKLDEATEGKRLGFSLNTRAIHAFPETRSQRKAGLPQSGHKFLLLDLP----HTVGPDSPQPKCDEKKPTPQAPTALGMVFNNSSPQSSAHKRPSPVPSPLSPRCSSPQ--------QHHRILLLPPLPREGEAVFNDYPSRKNGVSFGLPSADTLEAPSSTKVTETKGASPTSLRASQT--------WLVSEETSEKSLGSEKITAPPQHQLPPGVASEGFPCDNFNEQTAKDLPNKDGGTWVLGYRASPPCPFLLHEDKEKTSRSELYLDLNPDQSPTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELKTFHIRGEHALVTARLEETIDNLKQQLEKR-RGECEEMRDVCVSTDDDCFPKAFRNVCIQTDRET-------------------------------------------------------FLKPCDV-ESK----------TTRSSQIVPKKLTIS-LTQLSPSKDSKDFHAPLQTRECIPSSSQQKISPPAPPTPPPPPP--IPPPPPLPPG--------------------LGPLPPAPPISPVSAGSPLPPPPP---------------------------------------------------------PPPPPLPPSAGPPPPPPPPP-LPNVQTPPNSGGPPPPPPP----------------------PPPPGLAPPPPPGLS---------------------------------FGLSSSSSQCPRKPAIEPSCPMKPLYWTRIQINDKSQDATPTLWDSLEEPHIMDTSEFEYLFSKDTTQQKKKPLSEAYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELTKIRKYYETSRE-EDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRKVEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGMNLVDYVVKYYLRYYD------------------------------------QEAGTDKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEQQMRLVCKESPREYLQPFKDKLEEFFKKAKKEHKMEESHLENAQKSFETTVGYFGMKPKTGEK---EVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAEASVSKLTSEKKVETKKINPTASLKERLRQKEASVATN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05860-1", "uniprot_id": "FMN1_MOUSE", "id": "Q05860-1", "name": "Formin-1", "aln": "MEGTHCTLQLHN--------------------------------------------------------PIAELCYISFYLPKGEVRGFSYKGTVTLDRSNNAFHNCYQVREGPDITSLSQQPNEHPGDIFFKQTPTKNILTELYKLTAEKERLLDSLLRSDNILGVSMGSQEGKLQELSVILATGDEYFQSAGNWRRELPVSSLIRRSTQENKKPRRSGRRR----------ESPEELRQKRTRRKGRGCQESAFQMGKD-----QVCSSSSLSF-RARPNLRLLEERGNLVPRGTLTSS-LRRRESCPANILRTPDAD--------------------------LAFGNSGRTSEDTDL-EGPLSPDSSPTEVGDADVGGQLKSSHQQEPPQPNVSESHGKHAGAERWSSRTRKSKSLERTCSKKPVSKVVAKIQEP-------SAPVKRIVRAHHDGKGRVAYGPETQTEFIPKADFLTLPGGETETHSSGRLEEEQPGIKSLRSSAPERASITKEPASTEAAVNKVLRKVIESEKLDEATEGKRLGFSLNTRATHTFPETRSQRKAGLPQSGHKFLLLDLP----HTVGPDSPQPKCDEKKPTPQVPTALGMVFNNSSPQSSAHKRLSPVPSPLSPRCPSPQ--------QHHRILLLPPLPSEGEVVFNEYPSRKNDVSSGFPSADTLEPSSTTKVTETKGASPTSLRASQT--------WLVSEEASEKGLGPEKITAPPQHQLPPGIASEGFPCDNFKEQTAKDLPNKDGGVWVPGYRAGPPCPFLLHEEKEKTSRSELYLDLNPDQSPTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIETLQAQFELKTFHIRGEHALVTARLEEAIENLKQQLGKR-REGCEEMRDVCISTDDDCSPKAFRNVCIQTDRET-------------------------------------------------------FLKPCDA-ESK----------ATRSSQIVPKKLTIS-LTQLSPSKDSKDIHAPFQTREGTSSSSQHKISPPAPPTPPPLPPPLIPPPPPLPPG--------------------LGPLPPAPPIPPVCPVSPPPPPPP---------------------------------------------------------PPPTPVPPSDGPPPPPPPPPPLPNVLALPNSGGPPPPPPP----------------------PPP-GLAPPPPPGLS---------------------------------FGLSSSSSQYPRKPAIEPSCPMKPLYWTRIQINDKSQDAAPTLWDSLEEPHIRDTSEFEYLFSKDTTQQKKKPLSEAYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFTVDDSVVDLETLAALYENRAQEDELTKIRKYYETSKE-EDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRKVEIVTRASKGLLHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGMNLVDYVVKYYLRYYDQCKHHDQEASCRGKDLFSLYFHIAVHPQRKSGLELKQEAGTDKSVFPLPEPQDFFLASQVKFEDLLKDLRKLKRQLEASEQQMKLVCKESPREYLQPFKDKLEEFFKKAKKEHKMEESHLENAQKSFETTVGYFGMKPKTGEK---EVTPSYVFMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVETKKINPTASLKERLRQKEASVATN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68DA7-1", "uniprot_id": "FMN1_HUMAN", "id": "Q68DA7-1", "name": "Formin-1", "aln": "MEGTHCTLQLHK--------------------------------------------------------PITELCYISFCLPKGEVRGFSYKGTVTLDRSNKGFHNCYQVREESDIISLSQEPDEHPGDIFFKQTPTKDILTELYKLTTERERLLTNLLSSDHILGITMGNQEGKLQELSVSLAPEDDCFQSAGDWQGELPVGPLNKRSTHGNKKPRRSSGRR----------ESFGALPQKRTKRKGRGGRESAPLMGKD-----KICSSHSLPLSRTRPNLWVLEEKGNLLPNGALACS-LQRRESCPPDIPKTPDTD--------------------------LGFGSFETAFKDTGLGREVLPPDCSSTEAGGDGIRRPPSGLEHQQTGLSESHQDPEKHPEAE----KDEMEKPAKRTCKQKPVSKVVAKVQDL-------SSQVQRVVKTHSKGKETIAIRPAAHAEFVPKADLLTLPGAEAGAHGSRRQGKERQGDRSSQSPAGETASISSVSASAEGAVNKVPLKVIESEKLDEAPEGKRLGFPVHTSVPHTRPETRNKRRAGLPLGGHKSLFLDLP----HKVGPDSSQPRGDKKKPSPPAPAALGKVFNNSASQSSTHKQTSPVPSPLSPRLPSPQ--------QHHRILRLPALPGEREAALNDSPCRKSRVFSGCVSADTLEPPSSAKVTETKGASPAFLRAGQP--------RLVPGETLEKSLGPGKTTAEPQHQSPPGISSEGFPWDGFNEQTPKDLPNRDGGAWVLGYRAGPACPFLLHEEREKSNRSELYLDLHPDHSLTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKDVCISTDDDCPPKTFRNVCVQTDRET-------------------------------------------------------FLKPCES-ESK----------TTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASN-QQKALPPPPAS--------IPPPPPLPSG--------------------LGSLSPAPPMPPVSAGPPLPPPPP---------------------------------------------------------PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPP-------------------------PPGLAPPPPPGLF---------------------------------FGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKE-EELKLLDKPEQFLHELAQIPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKYYLRYYD------------------------------------QEAGTEKSVFPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEFFQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEK---EITPSYVFMVWYEFCSDFKTIWKRESKNISKERLKMAQESVSKLTSEKKVETKKINPTASLKERLRQKEASVTTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24120-1", "uniprot_id": "CAPU_DROME", "id": "Q24120-1", "name": "Protein cappuccino", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MALQLGKKLAQVLGSGAG--SPLTPGTMEPCAAGSGSPLANGELFNVSKAKKVELQNLSSRFTAAVT----------QTPPGVTSSTPNESGVTGPAG---------------------------------------PLGATTSSPSLETQSTVIISFKSSQTP----------------------------------------------------------------VQSQTNSAASENVEDDTAPLPLPPPPPGFGTPTTPLLSSNVLKKVASFTVE-------------------------KSSAGNNSSNPPNLCPTSDETTLLATPCSSSLT---------VATLPPEIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAYEKFEGQMLIKWLISTMQSNPKSSSGDANQELFN--------------------TLALQFCNNLKYVGVLKQISNEHLDCGFSPYEMYQWTHTEQP--------------------TTSLPLTPGKLDKVAAWPFSSTPSG--------------------------------------------IRALESASLASLGAGGVAGSLATIATASTAS---------------------------------------SDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPR------------------------------------------------RPSKRCVNLTELLNASEATVYEYNKTGAEGCVKSFTDAETQTESEDCEGTCKCGQSST----------------------------------------------------------------------------KVSDNESAKEDGEKPHAVAPPPPP-------PPPPLHAFVAPPPPPPPPPPPPPPLANYGAPPPPPPPPPGSGSAP------------------PPPPPAPIEGGGGIPPPPPPMS---------------------------------------------------------ASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRP-------------------LYWTRIVTSAPPAPRPP--------------------------------------SVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNIDEFTELFSRQAIAPVSKPK----ELKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIP------LDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRR-----------------------------------KEGVHPLEIRLPIPEPADVERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRR-NVSTKVEKSGRISLKERMLMRRSKN---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * . : .: * : : . : . . * . * . : . :: .. :. . . . . * .: . . . . : . : : .: . : . : : *: * : : . . : . :. :: . . : .. . . . . .. .* . . . :.. . : : .: . : ** . .. . : : .. . . .*. . . .. ***** * .*..*: .* * * ..*. . * * : . . ** * . **.* . . . . . . * :* . : :. :* .:**. : ** ***: : .** . * * : :*:*. :**: ***: ***: .:*::*: :* ***.**:* : : :* .*** :*.: . **:***** ::: *. :** **:*:: *.*.: : **:* : : .: * . .: ::.::*::*****.**: ******:.*:** ******* :. .*: ::* *: : . : :*:.** :. *:*:.**:. ::: .*::.: ..: * * * :***.::*:*. *. . . * : :. * * :: :.** : :*. .* * :* .*** **:* . : :* :* :: : : . : .:* :: : ", "identical_positions": 151, "similar_positions": 255, "identity": "8.4%" }, { "cls_id": "homologset.agr.FB:FBgn0000257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D2N9-1", "uniprot_id": "VP33A_MOUSE", "id": "Q9D2N9-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MAAHLSYG--RVNLNVLREAVRRELREFLDKCAGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGSRLPAADVKNI----IFLVRPRLELMDIIAENVLSED-----RRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARQVANMMVRMKREFTGS-----------QNSVFPVFDNLLLLDRNVDLLTPLASQLTYEGLIDEIYGIQNSYVKLPPEKFAPK--KQGGGSGGKDLP--------TEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARGSLANHTSIAELIKDVTTSEDFFDK---LTVEQEFMSG--IDTDKVNSYIEDCIAQKHPLIKVLRLVCLQSVCNSGLKQKVLDYYRREILQTYGYEHILTLNNLEKAGLLKAQTGGRNNYPTIRKTLRLWMDD----------------------VNEQNPTDISYVYSGYAPLSVRLAQLL------------------SRP-GWRSIEEVLRILPGPHFEERQPLPTG-----------LQKKRQPGEN---------RVTLVFFLGGVTFAEIAALRFLSQLEDG---GTEYVIATTKLMNGNSWIEALMEKPF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63615-1", "uniprot_id": "VP33A_RAT", "id": "Q63615-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MAAHLSYG--RVNLNVLREAVRRELREFLDKCAGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGSRLPAADVKNI----IFLVRPRLELMDMIAENVLSED-----RRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIYREEYSLDLIPFDGDLLSMESESAFKECYLEGDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARQVANMMVRMKREFTGS-----------QNSVFPVFDNLLLLDRNVDLLTPLASQLTYEGLIDEIYGIQNSYVKLPPEKFAPK--KQGGG-GGKDLP--------TEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARGSLANHTSIAELIKDVTTSEDFFDK---LTVEQEFMSG--IDTDKVNNYIEDCIAQKHPLIKVLRLVCLQSMCNSGLKQKVLDYYKREILQTYGYEHILTLNNLEKAGLLKAQTGGRNNYPTIRKTLRLWMDD----------------------VNEQNPTDISYVYSGYAPLSVRLAQLL------------------SRP-GWRSIEEVLRILPGPHFEERQPLPTG-----------VQKKRQPGEN---------RVTLVFFLGGVTFAEIAALRFLSQLEDG---GTEYVIATTKLINGSSWLEALMEKPF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AX1-1", "uniprot_id": "VP33A_HUMAN", "id": "Q96AX1-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MAAHLSYG--RVNLNVLREAVRRELREFLDKCAGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNI----IFFVRPRLELMDIIAENVLSED-----RRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARQVANMMIRMKREFTGS-----------QNSIFPVFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQNSYVKLPPEKFAPK--KQGDG--GKDLP--------TEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARGSLANHTSIAELIKDVTTSEDFFDK---LTVEQEFMSG--IDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDD----------------------VNEQNPTDISYVYSGYAPLSVRLAQLL------------------SRP-GWRSIEEVLRILPGPHFEERQPLPTG-----------LQKKRQPGEN---------RVTLIFFLGGVTFAEIAALRFLSQLEDG---GTEYVIATTKLMNGTSWIEALMEKPF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ID82-1", "uniprot_id": "A0A0R4ID82_DANRE", "id": "A0A0R4ID82-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MASHLFCG--RVNLNILREAARKDLREFLDKCSGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGGRIPSAAVKNI----VFFVRPRLELMDIIAENVSSED-----KLQP-REFHILFVPRRSLLCEQRLKEKGVLNSFTNIDEYILDLIPYDGDLLSMESESSFRECYLENDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARHVANMMLRMKREFAGS-----------HTQILPVFDTLLLLDRNVDLLTPLATQLTYEGLIDEIFGITNGYVKLPPEKFAQK--KQGEG--GKDLP--------TEPKKLQLNSAEELYAEIRDKNFNAVGAALSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARSSLANHTSIAELIKDITTSEVFFDS---LTVEQEFMTG--VDTDKVSTYIEDCIAQKDPLIKILRLVCMQSVCNNGLKQKVLDYYKREILQTYGYKHILTLKNLEKVGLLKPQSTMRNNYPTIRKTLKLWMED----------------------ANEQNPNDISYVYSGYAPLSVRLTQVL------------------ARP-GWRSIEEVLKMLPGPHFEERQQVPTG-----------LHKKRQPGEN---------RTTLVFFLGGVTYAEIAALRFLSHMEDS---GTEYIIATTKLINGTSWVKSLMDHPEENQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y1I2-1", "uniprot_id": "VP33A_DROME", "id": "Q9Y1I2-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MFPHLKGHGQRVNLQLLQEAACRELLQQLDRIEGS---KVIVLDETMIG----PLDLVTRPKLFADRGIR-LLALKPELHLPREVANV----VYVMRPRVALMEQLAAHVKAGG-----RAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYG-RIPKIYGKGEFAHRVWEHAKQLGRDERTL-----------YNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADD---LAAEQEFMVC--ADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISNLEKSGLLHLQTESR-AYSVLRKTLHLTVDD----------------------NVEIEPKDISYVHSFYAPLTARIVEHS------------------LKPLGWQTLKSQINNLPGPTFEDFQAQLVG-----------IGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDN---NVEFLIATTKVVNKHSFLDSLMSS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20795-1", "uniprot_id": "VPS33_YEAST", "id": "P20795-1", "name": "Vacuolar protein sorting-associated protein 33", "aln": "MNRFWNTKKFSLTNADGLCATLNEISQNDEVLVVQPSVLPVLNSLLTFQDLTQSTPVRKITLLDDQLSDDLPSALGSVPQMDLIFLIDVRTSLRLPPQLLDAAQKHNLSSLHIIYCRWKPSFQNTLEDTEQWQKDGFDLNSKKTHFPNVIESQLKELSNEYTLYPWDLLPFPQIDENVLLTHSLYNMENVNMYYPN-LRSLQSATESILVDDMVNSLQSLIFETNSIITNVVSIGNLSKRCSHLLKKRIDEHQTENDLFIKGTLYGERTNCGLEMDLIILERNTDPITPLLTQLTYAGILDDLYEFNSG-IKIKEKDMNFN------------------------------YKEDKIWNDLKFLNFGSIGPQLNKLAKELQTQYDTRHKAESVHEIKEFVD-SLGSLQQRQAFLKNHTTLSSDVLKVVETEEYGSFNKILELELEILMGNTLNNDIEDIILELQYQYEVDQKKILRLICLLSLCKNSLREKDYEYLRTFMIDSWGIEKCFQLESLAELGFFTSKTGKTDLHITTSKSTRLQKEYRYISQWFNTVPIEDEHAADKITNENDDFSEATFAYSGVVPLTMRLVQMLYDRSILFHNYSSQQPFILSREPRVSQTEDLIEQLYGDSHAIEESIWVPGTITKKINASIKSNNRRSIDGSNGTFHAAEDIALVVFLGGVTMGEIAIMKHLQKILGKKGINKRFIIIADGLINGTRIMNSIS--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : :: .. ..* * .: * : *: : . .:. :.: .*: :. : * . *: : * : : : : . : ::: :. * .:* :: : : :.* . ::. : : . . .* * . *.:: . *: ::: . : : : *::*:*. * ::** :**** *::*::: : .. :.: :.: . . :::: ::: :*. : * : *: : . . : ::* ***.**. * : : :**::: : . . : : . * * *:: : * . :* . ::***:*: . . ..:::* :: : ::. :* : : : .* : *:: :: : . *: :* : : : .: ::.:* .**: *:.: : :. :. * * . : . .: .*: *:** * .*** ::.* . . .::* : ::* :.:: ", "identical_positions": 71, "similar_positions": 205, "identity": "9.7%" }, { "cls_id": "homologset.agr.FB:FBgn0000259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P67870-1", "uniprot_id": "CSK2B_HUMAN", "id": "P67870-1", "name": "Casein kinase II subunit beta", "aln": "MSS-SEEVS----------------------------WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQ-SDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P67871-1", "uniprot_id": "CSK2B_MOUSE", "id": "P67871-1", "name": "Casein kinase II subunit beta", "aln": "MSS-SEEVS----------------------------WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQ-SDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P67874-1", "uniprot_id": "CSK2B_RAT", "id": "P67874-1", "name": "Casein kinase II subunit beta", "aln": "MSS-SEEVS----------------------------WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQ-SDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91398-1", "uniprot_id": "CSK2B_DANRE", "id": "Q91398-1", "name": "Casein kinase II subunit beta", "aln": "MSS-SEEVS----------------------------WISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQ-SDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASSFKSPVKAIR--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08182-1", "uniprot_id": "CSK2B_DROME", "id": "P08182-1", "name": "Casein kinase II subunit beta", "aln": "MSS-SEEVS----------------------------WVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDNPLQ-SDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGEAMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSLAYQIQLQAAANFKMPLRAQRGQPPKDEEPENNADTVPKRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38930-1", "uniprot_id": "CSK2C_YEAST", "id": "P38930-1", "name": "Casein kinase II subunit beta'", "aln": "MGSRSENVGTVTREGSRVEQDDVLMDDDSDSSEYVDMWIDLFLGRKGHEYFCDVDPEYITDRFNLMNLQKTVSKFSYVVQYIVDDLDDSILENMTHARLEQLESDSRKLYGLIHARYIITIKGLQKMYAKYKEADFGRCPRVYCNLQQLLPVGLHDIPGIDCVKLYCPSCEDLYIPKSSRHSSIDGAYFGTSFPGMFLQAFPDMVPKHPTKRYVPKIFGFELHKQAQLTRWQELQRLKLVEKLESKDVDLTKSGGFKT-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* **:*. *: * * :*:*:**:** :** *:*** .*:: *.:: .:: *:* :. **: . : *. :. **********:* :*: :* **: .*** ******: * :**:** **** ** ***.* *:* ****** *******.** *:: ..*: **:*::::**:::**::* * : * :* : ", "identical_positions": 96, "similar_positions": 58, "identity": "36.23%" }, { "cls_id": "homologset.agr.FB:FBgn0000261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04762-1", "uniprot_id": "CATA_RAT", "id": "P04762-1", "name": "Catalase", "aln": "MADSRDPASDQMKQWKEQRAPQKPDVLTTGGGNPIG-DKLNIMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAMLFPSFIHSQKRNPQTHL---KDPDMVWDFWSLCPE--SLHQVTFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLPVEEAGRLAQEDPDYGLRDLFNAIASGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPANYFAEVEQMAFDPS-NMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVN------CPYR------------ARVAN-YQRDGPMCMHDNQGGAPNYYPN-----------------------------SFSAPEQQG--SALEHHSQCSADVKRFNSAN-EDNVTQVRTFYTKVLNE-EERKRLCENIANHLKDAQ-LFIQRKAVKNFTDVHPDYGARVQALLDQYNSQKPKNAIHTYVQAGSHIAAKGKANL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24270-1", "uniprot_id": "CATA_MOUSE", "id": "P24270-1", "name": "Catalase", "aln": "MSDSRDPASDQMKQWKEQRASQRPDVLTTGGGNPIG-DKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHL---KDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIANGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQMAFDPS-NMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVN------CPYR------------ARVAN-YQRDGPMCMHDNQGGAPNYYPN-----------------------------SFSAPEQQR--SALEHSVQCAVDVKRFNSAN-EDNVTQVRTFYTKVLNE-EERKRLCENIAGHLKDAQ-LFIQKKAVKNFTDVHPDYGARIQALLDKYNAEKPKNAIHTYTQAGSHMAAKGKANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04040-1", "uniprot_id": "CATA_HUMAN", "id": "P04040-1", "name": "Catalase", "aln": "MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVG-DKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHL---KDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPS-NMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVN------CPYR------------ARVAN-YQRDGPMCMQDNQGGAPNYYPN-----------------------------SFGAPEQQP--SALEHSIQYSGEVRRFNTAN-DDNVTQVRAFYVNVLNE-EQRKRLCENIAGHLKDAQ-IFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PT92-1", "uniprot_id": "CATA_DANRE", "id": "Q9PT92-1", "name": "Catalase", "aln": "MADDREKSTDQMKLWKEGRGSQRPDVLTTGAGVPIG-DKLNAMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHVGKTTPIVVRFSTVAGEAGSPDTVRDPRGFAVKFYTDEGNWDLTGNNTPTFFIRDTLLSPSFIHSQKRNPQTHL---KDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGYRHMNGYGSHTFKLVNAQGQPVYCKFHYKTNQGIKNIPVEEADRLAATDPDYSIRDLYNAIANGNFPSWTFYIQVMTFEQAENWKWNPFDLTKVWSHKEFPLIPVGRFVLNRNPVNYFAEVEQLAFDPS-NMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVN------CPYR------------TRVAN-YQRDGPMCMHDNQGGAPNYYPN-----------------------------SFSAPDVQP--RFLESKCKVSPDVARYNSAD-DDNVTQVRTFFTQVLNE-AERERLCQNMAGHLKGAQ-LFIQKRMVQNLMAVHSDYGNRVQALLDKHNAEGKKNTVHVYSRGGASAVAAASKM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17336-1", "uniprot_id": "CATA_DROME", "id": "P17336-1", "name": "Catalase", "aln": "MAG-RDAASNQLIDYKNSQ-TVSPGAITTGNGAPIG-IKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHL---KDPDMFWDFLTLRPE--SAHQVCILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEVEQIAFSPA-HLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVN------CPYK------------VKIEN-FQRDGAMNVTDNQDGAPNYFPN-----------------------------SFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDK-CAKKRLVQNIAGHLSNAS-QFLQERAVKNFTQVHADFG---RMLTEELNLAKSSKF-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15202-1", "uniprot_id": "CATA_YEAST", "id": "P15202-1", "name": "Peroxisomal catalase A", "aln": "-----MSKLGQEKNEVNYSDVREDRVVTNSTGNPIN-EPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNL---RDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPS-TTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVN------CPYA------------SKFFNPAIRDGPMNVNGNFGSEPTYLANDK---------------------------SYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGAC-PQIQQRVYDMFARVDKGLSEAIKKVAEAKHASELSSNSKF----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06115-1", "uniprot_id": "CATT_YEAST", "id": "P06115-1", "name": "Catalase T", "aln": "------------MNVFGKKEEKQEKVYSLQNGFPYSHHPYASQYSRPDGPILLQDFHLLENIASFDRERVPERVVHAKGGGCRLEFELTDSLSDITYAAPYQNVGYKCPGLVRFSTVGGESGTPDTARDPRGVSFKFYTEWGNHDWVFNNTPVFFLRDAIKFPVFIHSQKRDPQSHLNQFQDTTIYWDYLTLNPE--SIHQITYMFGDRGTPASWASMNAYSGHSFIMVNKEGKDTYVQFHVLSDTGFETLTGDKAAELSGSHPDYNQAKLFTQLQNGEKPKFNCYVQTMTPEQATKFRYSVNDLTKIWPHKEFPLRKFGTITLTENVDNYFQEIEQVAFSPTNTCIPGIKPSNDSVLQARLFSYPDTQRHRLGANYQQLPVNRPRNLGCPYSKGDSQYTAEQCPFKAVN-FQRDGPMSYY-NFGPEPNYISSLPNQTLKFKNEDNDEVSDKFKGIVLDEVTEVSVRKQEQDQIRNEHIVDAKINQYYYVYGISPLDFEQPRALYEKVYND-EQKKLFVHNVVCHACKIKDPKVKKRVTQYFGLLNEDLG---KVIAECLGVPWEPVDLEGYAKTWSIASAN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * . **:*:** : :.:: *:**.:*:* **:*.*. **:*..:: : :.:: .***** *: *:.**.*****.: ****: * * . **** **:**. * ***:***:**::* :*. : **: : : : **: :*.*** * . *:.*..*:: * .*. * :.* :: *::.: * .:: .*** .*: : . : *.:. *:*.** .:* . :. *:**:*.: ::** .* :.* .* *:* ::** ** *: * :.* * :*:.***:*.*::*:***.*: ::*** *** : * ***.* * . *.* .. . . . : . :. * :: : .. :: : *: * ::.: . : :. . . : : : ", "identical_positions": 133, "similar_positions": 151, "identity": "22.66%" }, { "cls_id": "homologset.agr.FB:FBgn0000273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68182-1", "uniprot_id": "KAPCB_RAT", "id": "P68182-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "----------------------------------------------------------------------MGN-------TAIAKKGSEVES-------------------------------------VKEFLAKAKEDFLRKWENPPPSNAG---LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEEIRVSIT--EKCGKEFCEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68181-1", "uniprot_id": "KAPCB_MOUSE", "id": "P68181-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "----------------------------------------------------------------------MGN-------TAIAKKGSEVES-------------------------------------VKEFLAKAKEDFLRKWENPPPSNAG---LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEEIRVSIT--EKCGKEFCEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22694-1", "uniprot_id": "KAPCB_HUMAN", "id": "P22694-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "----------------------------------------------------------------------MGN-------AATAKKGSEVES-------------------------------------VKEFLAKAKEDFLKKWENPTQNNAG---LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEDIRVSIT--EKCAKEFGEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05132-1", "uniprot_id": "KAPCA_MOUSE", "id": "P05132-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "----------------------------------------------------------------------MGN-------AAAAKKGSEQES-------------------------------------VKEFLAKAKEDFLKKWETPSQNTAQ---LDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSIN--EKCGKEFTEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27791-1", "uniprot_id": "KAPCA_RAT", "id": "P27791-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "----------------------------------------------------------------------MGN-------AAAAKKGSEQES-------------------------------------VKEFLAKAKEDFLKKWEDPSQNTAQ---LDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSIN--EKCGKEFTEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17612-1", "uniprot_id": "KAPCA_HUMAN", "id": "P17612-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "----------------------------------------------------------------------MGN-------AAAAKKGSEQES-------------------------------------VKEFLAKAKEDFLKKWESPAQNTAH---LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSIN--EKCGKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZU3-1", "uniprot_id": "A0A8M9PZU3_DANRE", "id": "A0A8M9PZU3-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "----------------------------------------------------------------------MCDR------KSSRRHGGKRESRSSGESRSSGGSAEGGGGGGGGSGSGGGVEGPTLLVDVKEFLAKAKEDFLKKWENPAQNTAS---LDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCK-GPGDTSNFDDYDEEEIRVSIT--EKCGKEFAEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GPM4-1", "uniprot_id": "A0AC58GPM4_DANRE", "id": "A0AC58GPM4-1", "name": "cAMP-dependent protein kinase", "aln": "MDEISEEYFQRSGKHNRLAARRLLVQAPAGTVGISVRSLHVLLAFTRVSSGCSGFPHSPKTCGTGELARVMAQPKDPHFGHSSGTNSALQKLDTLASRFFYKCRKGNHDKGLENEGPHVSEHTVLWDTAMKETLAKAKEDFLNKWECQQKSTAC---LDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCR-GPGDTSNFDEYDEEVIRVSVS--EQCSKEFLDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12370-1", "uniprot_id": "KAPC1_DROME", "id": "P12370-1", "name": "cAMP-dependent protein kinase catalytic subunit 1", "aln": "----------------------------------------------------------------------MGNN-----ATTSNKKVDAAET-------------------------------------VKEFLEQAKEEFEDKWRRNPTNTAA---LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCK-GPGDTSNFDDYEEEALRISST--EKCAKEFAEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22612-1", "uniprot_id": "KAPCG_HUMAN", "id": "P22612-1", "name": "cAMP-dependent protein kinase catalytic subunit gamma", "aln": "----------------------------------------------------------------------MGN-------APAKKDTEQEES-------------------------------------VNEFLAKARGDFLYRWGNPAQNTAS---SDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYT-GPGDASNFDDYEEEELRISIN--EKCAKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05986-1", "uniprot_id": "KAPC_YEAST", "id": "P05986-1", "name": "cAMP-dependent protein kinase type 3", "aln": "----------------------------MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSSNT------PVEINGRNSGKLK------------------------------------EEASAGIC---LVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYMDLMKEF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06244-1", "uniprot_id": "KAPA_YEAST", "id": "P06244-1", "name": "cAMP-dependent protein kinase type 1", "aln": "----------------------------MSTEEQNGGGQKSLDDRQGEESQKG----ETSERETTATESGNESK------SVEKEGGETQEKP------------------------------------KQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDINYGVQGEDPYADLFRDF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06245-1", "uniprot_id": "KAPB_YEAST", "id": "P06245-1", "name": "cAMP-dependent protein kinase type 2", "aln": "-----------------------------------------MEFVAERAQPVG---QTIQQQNVNTYGQGVLQP------HHDLQQRQQQQQQ------------------------------------RQHQQLLT-----SQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . .*: :*** ****** ::: . .:*:* *.* :*::**:** :*: :*. : .**:: : *:* ::::: *: ***:** *:: **.: : ****:: *:.:*** ::*:*******:*:* :*::::******* * *:******:*:***:: :* ***::***::*:*:*** .*:.**: .:: **:*:...: :*. : * .** *: **:.* ***: * *:* : ** . * : : :::* * * **:* ** * ** : . : . : :*", "identical_positions": 119, "similar_positions": 105, "identity": "25.27%" }, { "cls_id": "homologset.agr.FB:FBgn0000274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68182-1", "uniprot_id": "KAPCB_RAT", "id": "P68182-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "-------------------------------MGNTAIAKKGSEVESVKEFLAKAKEDFLRK---------------WENPPPS-NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEEIRVSIT--EKCGKEFCEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68181-1", "uniprot_id": "KAPCB_MOUSE", "id": "P68181-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "-------------------------------MGNTAIAKKGSEVESVKEFLAKAKEDFLRK---------------WENPPPS-NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEEIRVSIT--EKCGKEFCEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22694-1", "uniprot_id": "KAPCB_HUMAN", "id": "P22694-1", "name": "cAMP-dependent protein kinase catalytic subunit beta", "aln": "-------------------------------MGNAATAKKGSEVESVKEFLAKAKEDFLKK---------------WENPTQN-NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEEEDIRVSIT--EKCAKEFGEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05132-1", "uniprot_id": "KAPCA_MOUSE", "id": "P05132-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------MGNAAAAKKGSEQESVKEFLAKAKEDFLKK---------------WETPSQN-TAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSIN--EKCGKEFTEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27791-1", "uniprot_id": "KAPCA_RAT", "id": "P27791-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------MGNAAAAKKGSEQESVKEFLAKAKEDFLKK---------------WEDPSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSIN--EKCGKEFTEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17612-1", "uniprot_id": "KAPCA_HUMAN", "id": "P17612-1", "name": "cAMP-dependent protein kinase catalytic subunit alpha", "aln": "-------------------------------MGNAAAAKKGSEQESVKEFLAKAKEDFLKK---------------WESPAQN-TAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSIN--EKCGKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22612-1", "uniprot_id": "KAPCG_HUMAN", "id": "P22612-1", "name": "cAMP-dependent protein kinase catalytic subunit gamma", "aln": "-------------------------------MGNAPAKKDTEQEESVNEFLAKARGDFLYR---------------WGNPAQN-TASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYAD--QPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYT-GPGDASNFDDYEEEELRISIN--EKCAKEFSEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16911-1", "uniprot_id": "KAPC2_DROME", "id": "P16911-1", "name": "cAMP-dependent protein kinase catalytic subunit 2", "aln": "-------------------------------MSQHTSQYVFNSKEDYNVILDNMSREFEER---------------WNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTIS-GAEDLSNFENFEFKDRYKSRI--NRHPELFANF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05986-1", "uniprot_id": "KAPC_YEAST", "id": "P05986-1", "name": "cAMP-dependent protein kinase type 3", "aln": "MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSSNTPVEINGRNSGKLKEEASAGIC---LVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNS--NTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYMDLMKEF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06244-1", "uniprot_id": "KAPA_YEAST", "id": "P06244-1", "name": "cAMP-dependent protein kinase type 1", "aln": "MSTEEQNGGGQKSLDDRQGEESQKG----ETSERETTATESGNESKSVEKEGGETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDS--NTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDINYGVQGEDPYADLFRDF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06245-1", "uniprot_id": "KAPB_YEAST", "id": "P06245-1", "name": "cAMP-dependent protein kinase type 2", "aln": "-------------MEFVAERAQPVG---QTIQQQNVNTYGQGVLQPHHDLQQRQQQQQQRQHQQLLT-----SQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDT--TPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . .: .** **** * *:: .** * :.*. :*::**: * :*: :*. .**:: : : : ::::: : ***:** :: :* : * ****:: *:.:*:* .:::*******:*:*:.*::::*****:* * * ******:*:***:: : ***::***::*:*:**: .* .** : *.:* *. : : *: *: * :.*:** ..* *:* * ** . * : : : :*: * * * * *: : :: . : . : :*", "identical_positions": 98, "similar_positions": 101, "identity": "24.32%" }, { "cls_id": "homologset.agr.FB:FBgn0000286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB91-1", "uniprot_id": "D4AB91_RAT", "id": "D4AB91-1", "name": "Zinc finger protein 575", "aln": "MLGGSVKSEAR------VSEPNPTSQDPETKEAHQFSCPPVSHQDLP-RPSQ----PAVSGSVPSGPRRRPPPQRPHRCPDCPKAFSYPSKLATHRLAHGGTRP-----------------------HPCPDCPKAFSYPSKLAAHR-LTHSG---------------------ARPHSCPHC-----------------------------------------PKAFGHRSKLAAHLWTHAPARP--------------------------------------------------------------------------------------------------------------------------YPCPDCPKSFCYPSKLAAHRHTHH-----ATDARPYPCPHCPKAFSFPSKLAAHRLCHDPP--------------------TAPSSQTTGRHRCSSCNQAFGQRRLLLVHQRSHHQPESQGERE---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TXZ1-1", "uniprot_id": "ZN575_MOUSE", "id": "Q3TXZ1-1", "name": "Zinc finger protein 575", "aln": "MLGGSVKSEVR------ASEPSPTCQDPETKAP---------HQDLP-RPNQ----PAASGSVPSRPRRRPPPQRPHRCPDCPKAFSYPSKLATHRLAHGGTRP-----------------------HPCPDCPKAFSYPSKLAAHR-LTHSG---------------------ARPHSCPHC-----------------------------------------PKAFGHRSKLAAHLWTHAPARP--------------------------------------------------------------------------------------------------------------------------YPCPDCPKSFCYPSKLAAHRHTHH-----ATDARPYPCPHCPKAFSFPSKLAAHRLCHDPP--------------------TAPSSQATGSHRCSSCNQAFGQRRLLLVHQRSHHQSEGQGERE---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XF7-1", "uniprot_id": "ZN575_HUMAN", "id": "Q86XF7-1", "name": "Zinc finger protein 575", "aln": "MLERGAESAAG------ATDPSPTGKEPVTKEAP--------HQGPPQKPSQSAPGPTASAGSPPRPRRRPPPQRPHRCPDCDKAFSYPSKLATHRLAHGGARP-----------------------HPCPDCPKAFSYPSKLAAHR-LTHSG---------------------ARPHPCPHC-----------------------------------------PKSFGHRSKLAAHLWTHAPTRP--------------------------------------------------------------------------------------------------------------------------YPCPDCPKSFCYPSKLAAHRHTHH-----ATDARPYPCPHCPKAFSFPSKLAAHRLCHDPP--------------------TAPGSQATAWHRCSSCGQAFGQRRLLLLHQRSHHQVEHKGERD---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20385-1", "uniprot_id": "CF2_DROME", "id": "P20385-1", "name": "Chorion transcription factor Cf2", "aln": "MIKSTTNPQEQRLPRPEDQSPAPPPPPPSSATTSTAAPATPTHQVATVIANMD---TLKTAFLPNLSMDPNVHVSPHYCPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQHPKLSHPCFNCDEKFGNAVDLDEHHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:. .* *. * : . ** . .. . :. * . ** ** * : *. *.::* * * *** :* : *. . .* *: *:*. .. : *.:* *: *:.:* *. : : : ******:* *..** **: * :.. ***.*.:* *:*: ...* * * . .:*. * ::*. : * * *:* : ", "identical_positions": 62, "similar_positions": 66, "identity": "12.09%" }, { "cls_id": "homologset.agr.FB:FBgn0000287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UJQ4-1", "uniprot_id": "SALL4_HUMAN", "id": "Q9UJQ4-1", "name": "Sal-like protein 4", "aln": "MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASEDEATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVPSEDFSGAVLSHQPTSPGSKDCHRENGGSSEDMKEKPDAESVVYLKTETALP--------------------------------------------PTPQDISYLAKGKVANTNVTLQALRG-TKVAVNQRSADALPAPVP-GANSIPWVLEQILCLQQQQLQQIQLTEQIRIQVNMWASHALHSSGA----GADTLKTLGSHMS------QQVSAAVALLSQKAGSQGLSLDALKQAK----LP----------------------HANIPSATSSLSPG--------LAPFTLKPDGTR---VLPNVMSRLPSALLPQ-APGSVLFQSPFSTVALDTS---------KKGKGKPPN-ISA----VDVKPKDEAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRH----PQVKANPQLFAEFQDK---VAAGNGIPYALSVPDPIDEPSLSLDSKPVLVT--TSVGLPQNLSS------------------------GTNPKDLTGGSLPGDLQPGPSPESEGGPTLPGVG------------------PNYNSPRAGG--------------------------FQGSGTPEPGSETLKLQQLVENIDK------------------------ATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGE-NGSTGAICHDDVIESIDVEEVSSQE------------APSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAPFNLQRQGS-----RENGSVE--SDGLTNDSSSLMGDQEYQSR-SPDILETTS-FQALSPANSQAESIKSKSPDAGSKAESSE-----------------------------------------------NSRTEMEGR---------------------------------------------SSLPSTFIRA------------------------PPTYVKVEVPGTFVGPST---------------LSPGMTPLLAAQP--RRQAKQHGCTRCGKNFSSASALQIHERTHTGEKP-FVCNICGRAFTTKGNLKVHYMTHGANNNSARRGRKLAIENTMALLGTDGKRVS--------------------EIFPKEILAPSVNVDP-VVWNQYTSMLNGGLAVKTNEISVIQSGGVPT-LPVSLG-ATSVVNNATVSKMDGSQSGISADV----EKPSATDGVPKHQFPHFLEENKIAVS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BX22-1", "uniprot_id": "SALL4_MOUSE", "id": "Q8BX22-1", "name": "Sal-like protein 4", "aln": "MSRRKQAKPQHINWEEGQGEQPQQLPSPDLAEALAAE----EPGAPVNSPGNCDEASEDSIPVKRPRREDTHICNKCCAEFFSLSEFMEHKKSCTKTPPVLIMNDSEGPVPSEDFSRAALSHQLGSPSNKDSLQENGSSSGDLK-KLGTDSILYLKTEATQP--------------------------------------------STPQDISYLPKGKVANTNVTLQALRG-TKVAVNQRGAEAPMAPMP-AAQGIPWVLEQILCLQQQQLQQIQLTEQIRVQVNMWAAHALHSGVA----GADTLKALSSHVSQQVSVSQQVSAAVALLSQKASNPALSLDALKQAK----LP----------------------HASVPSAASPLSSG--------LTSFTLKPDGTR---VLPNFVSRLPSALLPQ-TPGSVLLQSPFSAVTLDQS---------KKGKGKPQN-LSASASVLDVKAKDEVVLGKHKCRYCPKVFGTDSSLQIHLRSHTGERPYVCPICGHRFTTKGNLKVHLQRH----PEVKANPQLLAEFQDK---GAVSAASHYALPVPVPADESSLSVDAEPVPVTGTPSLGLPQKLTS------------------------GPNSRDLMGGSLPNDMQPGPSPESEAGLPLLGVG------------------MIHNPPKAGG--------------------------FQGTGAPESGSETLKLQQLVENIDK------------------------ATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTTVKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPESPCDFTAPEPVAVSE-NGSASGVCQDDAAEGMEAEEVCSQD------------VPSGPSTVSLPVPSAHLASPSLGFSVLASLDTQGKGALPALALQRQSS-----RENSSLEGGDTGPANDSSLLVGDQECQSR-SPDATETMC-YQAVSPANSQAGSVKSRSP-EGHKAEGVE-----------------------------------------------SCRVDTEGR---------------------------------------------TSLPPTFIRA------------------------QPTFVKVEVPGTFVGPPS---------------MPSGMPPLLASQPQPRRQAKQHCCTRCGKNFSSASALQIHERTHTGEKP-FVCNICGRAFTTKGNLKVHYMTHGANNNSARRGRKLAIENPMAALSAEGKRAP--------------------EVFSKELLSPAVSVDP-ASWNQYTSVLNGGLAMKTNEISVIQSGGIPT-LPVSLG-ASSVVSNGTISKLDGSQTGVSMPMSGNGEKLAVPDGMAKHQFPHFLEENKIAVS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIF4-1", "uniprot_id": "D3ZIF4_RAT", "id": "D3ZIF4-1", "name": "Sal-like protein 1", "aln": "MSRRKQAKPQHFQSD-----------------------------PEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVNESPASPPKTFPPGPPSLNNPDEQMKFVASKADQEDCGDLSEHKGLDREESMETEVPVATSSSSSNGG-------TLSSVTNIATPSCHSGSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQS-TKVAVAQFSQEARCGGASGGKLLISALMEQLLALQQQQIHQLQLIEQIRHQILLLASQNADLSAS-SVPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLP-PVQLPQSSSGT-IIPPSSGPSPNVSMVTATVPTPSSEKVASNAGASH--VSPPAVSASSSPAAFAISSLLSPASNPLLPQPTPANAVFPTPLPNIATTAEDLNALSALAQQRKSKPPN-VTA----FEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN---VPTSTGIPYGMSIP-PEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLTPFIKTEEPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEAEGSAVPPFGGKGEDSSVVS-SIPTAGSSALNSPVADGGAGG--TTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDK------------------------KATDPNECVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENME-----ECPEGS------------IPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS--LKSVENGSVEG--DVLTNDSSSVGGDVESQSSGSPAISESTSSMQALSPSNSTQEFHKSPNVEEKPQRVGPGEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCSRGFSTKGNLKQHMLTHQMRDLPSQLFEP-------SSNLGPNQNSAMIPASSLSSLIKTEVNGFVHVSPQDSKDAPTSHVPSGPLSSSATSPVLLPAL-PRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKP-FACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFP--------------------EMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPP-IPGSLGNGSSSPISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER74-1", "uniprot_id": "SALL1_MOUSE", "id": "Q9ER74-1", "name": "Sal-like protein 1", "aln": "MSRRKQAKPQHFQSD-----------------------------PEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVNESPASPAKTFPPGP-SLNDPDDQMKDAANKADQEDCSDLSEPKGLDREESMEVEVPVATTTTTTTGGSGGSGGSTLSGVTNITTPSCHSGCSSGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQS-TKVAVAQFSQEARCGGASGGKLLISTLMEQLLALQQQQIHQLQLIEQIRHQILLLASQSADLPAAPSIPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLP-HVQLPQSSSGTSIVPPSGGTSPNMSIVTAAVPTPSSEKVASNAGASH--VSSPAVSASSSP-AFAISSLLSPESNPLLPQPTPANAVFPTPLPNIATTAEDLNSLSALAQQRKSKPPN-VTA----FEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN---VPTSTGIPYGMSIP-SEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLTPFIKTEEPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEVEGSAVPPFGGKGEESNMASSAVPTAGNSTLNSPVADGGPGG--TTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDK------------------------KATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENME-----ECPEGS------------IPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS--LKSVENGSMEG--DVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPGMEEKPQRVGPGEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEP-------SSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDAPTSHVPQGPLSSSATSPVLLPAL-PRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKP-FACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFP--------------------EMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPP-IPGSLGSGSS-PISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSC2-1", "uniprot_id": "SALL1_HUMAN", "id": "Q9NSC2-1", "name": "Sal-like protein 1", "aln": "MSRRKQAKPQHFQSD-----------------------------PEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKNCTKNQLVLIVNENPASPPETFSPSP-PPDNPDEQMNDTVNKTDQVDCSDLSEHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQS-TKVAVAQFSQEARCGGASGGKLAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLASQNADLPTS-SSPSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLP-PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASH--VSNPAVSSSSSP-AFAISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPN-VTA----FEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN---IPTSTGIPYGMSIP-PEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDK------------------------KATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENME-----DCPEGS------------IPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS--LKSVENGSIEG--DVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEP-------SSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPAL-PRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKP-FACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFP--------------------EMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPP-IPGSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QI36-1", "uniprot_id": "F1QI36_DANRE", "id": "F1QI36-1", "name": "Sal-like protein 1", "aln": "MSRRKQAKPQHFQSD-----------------------------SQLV-LAEHNGDTETNPDDSPCKDSGAHVCSRCCAEFFELSDLEQHQKNCTKNQLVLIVNENPVSPSGTFSPGS-SPHNPDEQMNDTTNNTDQAELTDLLEQNILDKEEAMDTEMSGVSAPHN-DGNGRMAGSSPLSGVGTGHGTLGSTGSNLGSSVISASLPQLGNLTELGNFSMINSNVIIENLQS-TKVAVAQFSQETRATGGQ--RVAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLASQSPELQAP-PSSSPVTLGSGTSPLTTLSSHLSQQLAAAAGLAQSIASQSASISSLKQMANVAQLPQSNSSVGESSQSLAAPG-----PAPVNAQPLEKRPGNAGSLHPPLGNPSLAKSSTP-AFAMGNLLNPVANTLLPQPPPGNPIFSSALPSVGSTVEDLNSLAALAQQRKGKPPN-VSS----FEPKSSSEDTFFKHKCRFCGKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN---IPTSTGIPYGMSMP-PEKPVTSWLDSKPVLSTLTSSVGMLLPPTIPSLPPFIKKEENNSLAIS----SPSHSAKSDSGPADTPMKNTDSVLEEGESTTLPTSNGKAEENNQSSNLLSNMSSAVEGTIEYTTSNSP--PMATNPLMPLMSEQFKAKFPFGGLLDPLQGSETSKLQQLVENIDR------------------------KVADPNECVICHRILSCQSALKMHYRTHTGERPFKCKVCGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPDNYPESMGSDAGSFDERNIDDLDNFSDDNMEGI--EDGPDSS------------IPDTPKSVDASQDSLCSSPT-LHESFGMDERIQEKSANHGAGEEVQYDQ-GKSVENGLVEG--DRFTNDSSSLGGDIESQSAGSPAVSESTSSMQAPSPSNGIFQQQKSPSMEDRQQRALSLEHISASLMHSNSASPGALDLTSVNSSK----DPISMLFPFRERGTLKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPNTSL---ASSLASSPTPSLLSVGPLSSMMKTEVNGFLHGLQPEVKDLPPALVT----SSASTSPVLSAAP-PRRTPKQHFCTTCGKTFSSSSALQIHERTHTGEKP-FACTICGRAFTTKGNLKVHMGTHMWNSAPARRGRRLSVDGPMAFLGTNPVKFP--------------------ELFQKDLSSRAGNGDPTSFWNQYAAAFSNGLAMKTNEISVIQNGGLPPPLSGSVGNGGSSPIGGLTGSMEKLHNSEPNPALAGLEKMANTENGTHFRFTRFMED-KEIVTN----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4ADE6-1", "uniprot_id": "D4ADE6_RAT", "id": "D4ADE6-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISD--------------------------------------CEGPSASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNACCTDPPVMVIIGGQENPSNSSVSSVPRPEGHSRPQVMDTEHSNLPDSGSSGPPDPAWGSERRGEESSGQ----------------------------------------FLVAGTGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSS-GAEPPK----------------------QAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKP---------KNGSGELGYG--------EVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDY---VITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPG------LPTFNKFVLMKAVEPKSKVDENTPPGSEGSAISGVADSGSATRMQLSKLVTSLPSWALLTNHLKSTGS------------------FPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVASTASGAPTTSAPAPSSSAS-GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGSTLPEGGGVAQE--------------------------NSSEQS------------TASGPGSFPQPQAQQPSAEEEISEEEEE-DEEEEEDVTDEDSLAGRGSE-SGGEKAISVRGDSEEVSGAEEEAATSGAAPTNGKEVDNNEKATQQALPPPPPPPDNLDRPQPMEQGPSDVSGG---------------------------------------------MEEEAKLEGT-------------------------------------------------------------------------------SSPMAALPQEGEGTSTPS----------------VEELNLPEAMKKEPGESSSRKACEVCGQSFPTQTALEEHQKTHPKDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAPHG----PQNIATLSLVPGCSS--------------------SIPSPGLSPFPRKDDPAIP------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX96-1", "uniprot_id": "SALL2_MOUSE", "id": "Q9QX96-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISD--------------------------------------CEGPSASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNSCCTDPPVMVIIGGQENPSNSSASSAPRPEGHSRSQVMDTEHSNPPDSGSSGAPDPTWGPERRGEESSGQ----------------------------------------FLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGAASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSS-GAEPPK----------------------QAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKP---------KNGSGELGYG--------EVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDY---VITSSGLPYGMSVPPEKAEEEAGTPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPG------LPTFNKFVLMKAVEPKSKADENTPPGSEGSAIAGVADSGSATRMQLSKLVTSLPSWALLTNHLKSTGS------------------FPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVASTASGAPTTSAPAPSSSAS-GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGSALSEGGGAAQE--------------------------NSSEQS------------TASGPGSFPQPQSQQPSPEEEMSEEEEE-DEEEEEDVTDEDSLAGRGSE-SGGEKAISVRGDSEEVSGAEEEVATSVAAPTTVKEMDSNEKAPQHTLPPPPPPPDNLDHPQPMEQGTSDVSGA---------------------------------------------MEEEAKLEGT-------------------------------------------------------------------------------SSPMAALTQEGEGTSTPL----------------VEELNLPEAMKKDPGESSGRKACEVCGQSFPTQTALEEHQKTHPKDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAPHG----PQNIATLSLVPGCSS--------------------SIPSPGLSPFPRKDDPTMP------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y467-1", "uniprot_id": "SALL2_HUMAN", "id": "Q9Y467-1", "name": "Sal-like protein 2", "aln": "MSRRKQRKPQQLISD--------------------------------------CEGPSASENGDASEEDHPQVCAKCCAQFTDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEESSGH----------------------------------------FLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPK----------------------QAFFHLYHPLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKP---------KNGSGELSYG--------EVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDY---VITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATAPG------LPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGS------------------FPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQE--------------------------NGSEQS------------TVSGARSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSE-SGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGG---------------------------------------------KEEGGKPERS-------------------------------------------------------------------------------SSPASALTPEGEATSVTL----------------VEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHG----PQNIAALSLVPGCSP--------------------SITSTGLSPFPRKDDPTIP------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKH3-1", "uniprot_id": "Q9VKH3_DROME", "id": "Q9VKH3-1", "name": "", "aln": "MCSIFRNRINYRGTG------------------------------------------GTRSGSGERERDRDRDRDRDRDRERDRDTLLAKELDADSNN-----NGTEPQMEAEAVPESDTERETAEERGEEQEPENSNEALDLSLISSGGRESLPG-----------------------------------------------------------------SGHVSLEALQH-TKVAVAQFAATAMAGNHQ--SADLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAEAAALGRHSH-----SDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDQESRREENS------------------------------KTDKRGTEDRKAEPEGYQSMMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQM---------QEEYSEYAS----------KEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSGQGQVQGEQYPIRLPFAPPVAPVGQEQHQNQVEEPEEIRQEIPVPQAEDLSKPMVKEKEKSHSPVERVKTPKEVKTDAALPSSEKPEKEISKPVVTSSRRNGSVRKRQTSAVSPPQEDRERDLVEHLHIAKLVRRSSAS-RESQPAEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIEN------------------------KLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQGAPAANPGEAERLGIEDQNSNKSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATPHPLERERDREKERERRIPNDCSDERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGRIFATGLANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPQCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGTGATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKP-FQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPNSGQGHPGSSAEQEFMQRRPELFFPYLPPFFNGLPPKPGELSPGAFPNIPPPPFANGGKYPYPPGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNDESESRDAEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : : . . : : . . : :: . . . : . . . :: * :. * . :. : . : :*:::: *:*: ::: *: : . . . . : . . .: .. * . :: .: :*:*::* *:**: *:*************: * :** :*:*:****** :** * : * .: . . :... * : . : *** ******::*:. .**:*::* :::** :*::* * *****:**:*****:*:***::* *: .. : * .**:*::**:*.: ****:*:* .: .. . . . . . . . : . : . . . :. .. . . .. . :: * * : *.: :**: * :**. : * * * .* :.* :..** * . : . : . . . .* ", "identical_positions": 111, "similar_positions": 166, "identity": "7.59%" }, { "cls_id": "homologset.agr.FB:FBgn0000289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UE3-1", "uniprot_id": "ZN546_HUMAN", "id": "Q86UE3-1", "name": "Zinc finger protein 546", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MQVDPPLHG----------PPNDFLIFQIIPLHSLSIMPRFLWILCFSMEETQGELTSSCGSKTMANVSLAFRDVSIDLSQEEWECLDAV--QRDLYKDVMLENYSNLVSLG-YTIPKPDVITLLEQEKEPWIVMR------EGTRNWFTDLEYKYITKNLLSEKNVCKIYLSQLQTGEKSKNTIHEDTIFRNGLQCKHEFERQERHQMGCVSQMLIQKQ----------------ISHPL-HPKIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFRLQTELTRHHRTHTGEKPYECKECGKAFICGYQLTLHLR-THTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAFIHSNQFISHQRIHTS---ESTYICKECGKIFSRRYNLTQHFKIHTGEKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPYECTECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICSYRLTLHQRIHTGE-----LPYECKECGKTFSRRYHLTQHFRLHTG---EKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKECGKAFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQRNHISEEVLCIM------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86YE8-1", "uniprot_id": "ZN573_HUMAN", "id": "Q86YE8-1", "name": "Zinc finger protein 573", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPVLEPHQVGLIR-----------------SYNSKTMTCFQELVTFRDVAIDFSRQEWEYLDPN--QRDLYRDVMLENYRNLVSLGGHSISKPVVVDLLERGKEPWMILR------EETQ--FTDLD-----------------------------------------LQC---------EIISYIEVPTYETD----------------ISSTQ-LQSIYKREKLYECKKCQKKFSSGYQLILHHRFHVIER----------------------------PYECKECGKNFRSGYQLTLHQRFHT----------------------------GEKPYECTECGKNFRSGYQLTVHQRFHTGEKTYECRQCGKAFIYASHIVQHERIHTGGKPYECQECGRAFSQGGHLRIHQRVHTGEKPYKCKECGKTFSRRSNLVEHGQFHTDEKPYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGYTTASYFLLHQR-IHKGGKPYECKECKKTFT----------------------------LYRNLTRHQNIHTGEKLFECKQCGKTYTTGSKLFQHQKTHTG---EKPYECKECGKAFSLYGYLKQHQKIHTGMKHFECKECKKTFTLYRNLTRHQNIHTGKKLFECQECGKAYSTGSNLIQHRKTHTGEKPYKCKECGKTFSLHGYLNQHQKIHTGMKPYECKVCRKTFTFYRNLTLHQSIHTDE-----KPFECKECGKTFRRSSHLTAHQSIHAD---KKPYECKECGKAFKMYGYLTQHQKIHTGGKPYECKECGKAFSRASNLVQHERIHTGEKPYVCKQCGKTFRYGSALKAHQRIHRSIKV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14709-1", "uniprot_id": "ZN197_HUMAN", "id": "O14709-1", "name": "Zinc finger protein 197", "aln": "MTRENVAHNALRQEGLVKGKDDTWKWGTSFQGSSSSVWETSHLHFRQLRYHETSGPQEALSRLRELCRRWLRPEARTKAQILELLVLEQFLSILPGEIRTWVQLHHPGSGEEAVALVEELQKDLDGPAIQVPVLVKDQDTLQKVVSAPGTTLPPVLPGSHIAAEICPHPPTDLVAFNLQDPQHDSPAPEASALS--QEENPRNQLMALMLLTAQPQELVMFEEVSVCFTSEEWACLGPI--QRALYWDVMLENYGNVTSLEWETMTENEEVTSKPSSSQRADSHKGTSKRLQGSVPQVLDFEEECEWQVLASQWGNETDERADTVKKVSLCERDKKKRTPPEKQGQKWKELGDSLTFGSAISESLIGTEGKKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPYKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRHSGERPYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQR-FHTGENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKTFIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTG---EKPFECSECGRAFSSNRNLIEHKRIHSGEKPYECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYRSNLIAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHTGE-----KPYKCNECGKDFSQNKNLVVHQRMHTG---EKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHTIEEFSWLQNTNESKIEIQKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2VY69-1", "uniprot_id": "ZN284_HUMAN", "id": "Q2VY69-1", "name": "Zinc finger protein 284", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMFKEAVTFKDVAVVFTEEELGLLDVS--QRKLYRDVMLENFRNLLSVG-HQLSHRDTFHFQREEK----------------------------------------------------------------------------FWIMETATQREGNSG-----------------GKIQTELESVPETGPHEEWSCQQIWEQTASELTR------------------------------------PQDSIS-SSQFSTQ---------------------------------------GDVPSQVDAG------------LSIIHIGETPSEHGKCKKFFSDVSILDLHQQLHSGKISHTCNEYRKRFCYSSALCLHQKVHMGEKRYKCDVCSKAFSQNSQLQTHQRIHTGEKPFKCEQCGKSFSRRSGMYVHCKLHTGEKPHICEECGKAFIHNSQLREHQR-IHTGEKPFKCYICGKSFHS----------------------------RSNLNRHSMVHMQEKSFRCDTCSNSFGQRSALNSHCMDHTK---EKLYKCEECGRSFTCRQDLCKHQMDHTGDKPYNCNVCGKGFRWSSCLSRHQRVHNGETTFKCDGCGKRFYMNSQGHSHQRAYREEELYKCQKCGKGYISKFNLDLHQRVHTGERPYNCKECGKSFRWASGILRHKRLHTGE-----KPFKCEECGKRFTENSKLRFHQRIHTG---EKPYKCEECGKGFRWASTHLTHQRLHSREKLFQCEDCGKSSEHSSCLQDQQSDHSGEKTSKCEDCGKRYERRLNLDMILSLFLNDI-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UK13-1", "uniprot_id": "ZN221_HUMAN", "id": "Q9UK13-1", "name": "Zinc finger protein 221", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MISPSLELLHSGLCK----------------FPEVEGKMTTFKEAVTFKDVAVVFTEEELGLLDPA--QRKLYRDVMLENFRNLLSVG-NQPFHQDTFHFLGKEK----------------------------------------------------------------------------FWKMKTTSQREGNSG-----------------GKIQIEMETVPEAGPHEEWSCQQIWEQIASDLTR------------------------------------SQNSIRNSSQFFKE---------------------------------------GDVPCQIEAR------------LSISHVQQKPYRCNECKQSFSDVSVFDLHQQSHSGEKSHTCGECGKSFCYSPALHIHQRVHMGEKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQLQEHQR-IHTGEKPFKCDICGKSFRV----------------------------RSRLNRHSMVHTGEKPFRCDTCGKNFRQRSALNSHSMVHIE---EKPYKCEQCGKGFICRRDFCKHQMVHTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRSHNGEKPYNCEECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQRLHSGE-----KPFKCEECGKRFTQSSQLHSHQTCHTG---EKLYKCEQCEKGYNSKFNLDMHQRVHGGERPYNCKECGKSFGWASCLLKHQRLHSGEKPLKSGVWEEIYSEFTASFTSVSLCGRKAI----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYD1-1", "uniprot_id": "A8DYD1_DROME", "id": "A8DYD1-1", "name": "", "aln": "-----------------------------------------------------------------MCAAQNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGGASTVVKKQDNNQQVLSLDKNYLLVDPATAAAAAAAAGGDSGLAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHHQTHTITAADGSHHHASGGTPSFCSVG------GATTLLGDILPG---------------------------------------------ISVQVQKVIQGLEDNEDSQG----------------EAPNLKLEPGTLELSPKTELQESMHFSETDATIKKER----------------------------------PYSCDECGKSFLLKHHLTTHARVHT----------------------------GERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIH-GKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNG--VNPNTSSATIIANQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQEAATQQQLATAGEQQQVQVQIMPDGQIHGKVIKYEICRNVMPEDQQQEQADMNAE-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .. : .. :. : :::::. . . : . : : . .. .. * *: * * : . . * : * : *.: *: .. * * : * * *.:.* :: : *. *.: * .: * :.* :*: * :** .* : * : * *: *: * *** : : * * *.* . * * : * : : :: . . : . . : * :** * : * *:* * . * : :: . : .. * : : :: : : .. * .*** * * * *.. :* :.: *: * : .:: .. : : ", "identical_positions": 60, "similar_positions": 111, "identity": "5.74%" }, { "cls_id": "homologset.agr.FB:FBgn0000299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6Q3-1", "uniprot_id": "F1M6Q3_RAT", "id": "F1M6Q3-1", "name": "", "aln": "MDRVRFSASGLPLRGWLLLAT----VTVGLLAQSVLGGVK---------------------------KSDVPCGGRDCSGGCQCFPEKGARGQPGEVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGTGGFPGLPGPQGPKGQKGEP----YALSKEDRDKYRGEPGEPGSVGYQGPPGRPGPIGQMGPMGAPGRP-----GPPGPPGPKGQP-------------------GNRGLGFYG------EKGEKGDVGQPGPNGIPSD--ITLIGPTPSTYHPDMYKGEKGSQGEPGIPG-------------ITLKGE---EGIMGFPGTRGFPGLDGEKGVSGQKGSRGLDGF-QGPSGPRGPKGERGELGPPGPPAYSPHP--------SLAKGARGDPGFQGAHGEPGSRGEPGDPGPVGPPGLSIGDEDSKRGLPGEMGPKGFSGEPGP---SAY-YPGPPGADGKPGPQGLPGPAGPPGP-DGFLFGLKGSEGRVGYPGPSGFPGGRGQKGWKGEAGDC-----------QCG---QVIPGLPGLPGPKGFPGVNGEFGKKGDQGDPGLHGIPGFPGFKGAPGIAGAPGPKGVKGDSRTIT---TKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPG-DGIKGPPGDAGLPGTPGTKGFPGEVGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGTPGQADCDTGVKRPIGGGQQVVIQPGCVEGPAGSPGQPGPPGPTGAKGIRGIPG---FPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGAPGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLSGPPGQHGFPGAPGREGPLGLPGSPGLGGLPGDRGEPGEPGEPGPVGMKGVSGDRGDAGVSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRPGFP---GIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPG--PPPLILPGMKDIK-GEKGDEGPMGLKGYLGLKGIQGMPGVPGLSGIPGLPGRPGFIKGAKGDIGVPGTPGLPGFPGVSGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDT-VDLPGSPGLKGERGVTGIPGLKGLFGEKGAEGDVGFPGITGMAGAQGSPGLKGQTGFPG-LTGLQGPQGEPGRIGIPGDKGDFGWPGVPGRPGIPGIRGISGLHGLPGTKGFPGSPGVD-AHGDPGFPGPTGD--RGDRGEANT--LPGPVGAPGQKGEQGIPGERGPVGSPGLQGFPGISPPSNISGLPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDPGPQGQPGVHGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIP-QKIAVQPGTMGPQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPIGQEGEPGRPGSPGLPGMPG-RSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLP--MMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQN-FQSTPSADTLKAGLIR-THISRCQVCMKNL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08122-1", "uniprot_id": "CO4A2_MOUSE", "id": "P08122-1", "name": "Collagen alpha-2(IV) chain", "aln": "MDRVRFKASGPPLRGWLLLAT----VTVGLLAQSVLGGVK---------------------------KLDVPCGGRDCSGGCQCYPEKGARGQPGAVGPQGYNGPPGLQGFPGLQGRKGDKGERGVPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGSGGFPGLPGPQGPKGQKGEP----YALSKEDRDKYRGEPGEPGLVGYQGPPGRPGPIGQMGPMGAPGRP-----GPPGPPGPKGQP-------------------GNRGLGFYG------QKGEKGDIGQPGPNGIPSD--ITLVGPTTSTIHPDLYKGEKGDEGEQGIPG-------------VISKGE---EGIMGFPGIRGFPGLDGEKGVVGQKGSRGLDGF-QGPSGPRGPKGERGEQGPPGPSVYSPHP--------SLAKGARGDPGFQGAHGEPGSRGEPGEPGTAGPPGPSVGDEDSMRGLPGEMGPKGFSGEPGS---PAR-YLGPPGADGRPGPQGVPGPAGPPGP-DGFLFGLKGSEGRVGYPGPSGFPGTRGQKGWKGEAGDC-----------QCG---QVIGGLPGLPGPKGFPGVNGELGKKGDQGDPGLHGIPGFPGFKGAPGVAGAPGPKGIKGDSRTIT---TKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPG-DGIKGPPGDAGLPGVPGTKGFPGDIGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGPPGTPGQRDCDTGVKRPIGGGQQVVVQPGCIEGPTGSPGQPGPPGPTGAKGVRGMPG---FPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGTTGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGTRGDAGLPGQPGLKGLPGETGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGQSGPPGQHGFPGTPGREGPLGQPGSPGLGGLPGDRGEPGDPGVPGPVGMKGLSGDRGDAGMSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRQGFP---GTKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPG--PPPLILPGMKDIK-GEKGDEGPMGLKGYLGLKGIQGMPGVPGVSGFPGLPGRPGFIKGVKGDIGVPGTPGLPGFPGVSGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDT-VDLPGSPGLKGERGITGIPGLKGFFGEKGAAGDIGFPGITGMAGAQGSPGLKGQTGFPG-LTGLQGPQGEPGRIGIPGDKGDFGWPGVPGLPGFPGIRGISGLHGLPGTKGFPGSPGVD-AHGDPGFPGPTGD--RGDRGEANT--LPGPVGVPGQKGERGTPGERGPAGSPGLQGFPGISPPSNISGSPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGQKGWVGDPGPQGQPGVLGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIP-QKIAVQPGTLGPQGRRGLPGALGEIGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQEGEPGRPGSPGLPGMPG-RSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLP--MMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDTSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQN-FQSTPSADTLKAGLIR-THISRCQVCMKNL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08572-1", "uniprot_id": "CO4A2_HUMAN", "id": "P08572-1", "name": "Collagen alpha-2(IV) chain", "aln": "MGRDQRAVAGPALRRWLLLGT----VTVGFLAQSVLAGVK---------------------------KFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEP----YALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRP-----GPPGPPGPKGQQ-------------------GNRGLGFYG------VKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRG-------------ISLKGE---EGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGY-QGPDGPRGPKGEAGDPGPPGLPAYSPHP--------SLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGI---PAL-YGGPPGPDGKRGPPGPPGLPGPPGP-DGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGEC-----------RCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTIT---TKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPG-DGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPG---FAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFP---GSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPG--PPPVILPGMKDIK-GEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDT-INLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPG-LTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSD-IHGDPGFPGPPGE--RGDPGEANT--LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIP-QKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPG-RSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLP--MMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQS-FQGSPSADTLKAGLIR-THISRCQVCMKNL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z838-1", "uniprot_id": "A0A8M6Z838_DANRE", "id": "A0A8M6Z838-1", "name": "", "aln": "MEGENHLQHWNTLRCFLLCLV----VLI--LTTDVNAGVK---------------------------KSTGPCGGRDCSGGCQCYPEKGARGLPGPLGPQGPTGPKGRQGEPGLQGPKGMKGEHGEAGFVGPKGSVGMEGVPGFNGADGVPGHPGPSGARGKAGPDGCNGTRGDSGMPGFPGLEGGQGTPGWPGMKGEKGDP----LEVWVY-MERFRGDPGPAGFPGIVGPTGDPGYRGLPG---FQGPW-----GPQGLKGAKGQK-------------------GERTKILKG------VKGELGEIGEPGPPGVFSQ-----TSPIPSDWQGD--KGKMGSKGDKGDLGY------------LSTKAE---SGVSGFAGARGNPGLDG---WPGPRGDTGLPGF-PGNNGRKGDVGE------PGELVGSPFD--------DTGVGPPGPPGERGPVGNYGRKGAKGQPGPPGPP-PYGQQTVELWGPEGPRGPKGASGETGE---PGN-PATQPGP---PGPDGSPGSVGPPGP-KGSLEEYFK-----GSPGHRGRPGSAGKKGPKGDHGLC-----------ECS--VKPPPGPPGPPGDSGDPGMAGEWGQQGDQGDPGTKGANGLP---GFPGTEGLPGPKGRKGELMEAV---QKGSAGDPGDPGHSGFPGEQGRPGIDGRDGEPGFRGPPG-EGPVGEPGAKGYSGPPGRSGLIGPKGNPGQVLGATKGLSGLPGDDGQTGPDGRTGPPGPPG-----DCSS------RGGSQWSIPVECIGDP-GPPGESGLPGPRGLEGFPGVPGPKGTAGFSGDLGDKGERGEPGRGGPPGPKGFTGPRGDLGYPGTKGVKGPPGLSGKPGLDGASGGKGEHGEVFGASSGAPGDPGLPGHRGDTGLTGDPGSPGYFGMEGMPGMTGLKGESGPPGLQGEQGRPGPPGTFGFPGQTGYTGPPGPPGNIGEPGPSGRRGDQGEPGLIGARGVKGAIGDPGNIGVTGNIGPPGDQGETGGPGFFGLPGLKGSKGGQGMTGFPGKTGERGLKGFS---GTKGEIGLPGHQGAKGAPGSPGQKGDRGLTGPPGDKPVIHITPHMKEVMKGSKGDHGNMGDPGFTGPRGTKGFPGIPGGEGKDGHPGEPSVVKGVKGLPGEPGLEGPKGMPGPTGLPGIEGFPGMSGPKGNKGSSGAYGRPGDSGIKGFKGDLGPT-ISLPGSTGLRGETGHPGSTGAKGLYGMPGERGSSGLDGIEGMKGYQGEPGTVGPPGSDG-LQGFPGSQGHKGRSGDPGQTGTTGIQGQPGQKGFPGLKGIFGLDGLKGQKGNQGVPGTD-NWGQPGNPGTKGE--LGETGIPST--TTGVPGSLGHKGTTGDPGNKGEIGQRGVPGPQGQQGFSDIKGTQGDYGFPGIKGIPGFPGTRGTPGIPSPFGAKGDRGNVGDFGLFGEKGVQGDRGEKGSSGESGVSGRKGDKGEPGMMGFPGRRGFQGDRGPFGPKGDTGPPGFPGLPGAKGYPPVP-QKLPGEQGPPGQMGIQGPLGRNGNPGPAGPPGDPGFVGPSGHKGMPGLPGIPGSPGFRGEPGSMGHSGLQGEQGTRGRPGIPGPLGMAG-RSVNVGYLLVKHSQSEEIPMCPQGMSLLWMGYSLLYFEGQEKAHNQDLGLAGSCLPRFNTMPFLYCNPGDICYYASRNDKSYWLSTTQPIP--MMPVEESEIKPYISRCSVCEAPSVAIAVHSQDTTIPNCPVGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRTTPFIECNGAKGTCHYFANKHSFWLTSIDES--FQSSPSSETLKAGQLL-SRISRCQVCMKNL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q14031-1", "uniprot_id": "CO4A6_HUMAN", "id": "Q14031-1", "name": "Collagen alpha-6(IV) chain", "aln": "-----------MLINKLWLLL----VTLCLTEELAAAGE-K--------------------------SYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDP----VLAPGSFK-GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPG-----LQGPPGPPGPLGPD-------------------GNMGLGFQG------EKGVKGDVGLPGPAGPPPS-----TGELEFMGFPKGKKGSKGEPGPKGFPGISGPPG-FPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGF-PGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV----ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPA-LSGVP-GALGPQGFPGLKGDQGNPGR---TTIGAAGLPGRDGLPGPP---GPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFC-----------ACD-GGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST---IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKG-----------------ITLPCIIPG-SYGPSGFPGTPGFPGPKGSRGLPGTPG------QPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR---GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVG--IPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQT-VEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPG-VAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPS-ITGVPGPAGLPGP--KGEKGYPGI--GIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTA-EAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG-QSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIP--MMPVSQTQIPQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLH-TRVSRCQVCMKSL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AVK5-1", "uniprot_id": "B1AVK5_MOUSE", "id": "B1AVK5-1", "name": "", "aln": "------------MHPGLWLFL----VSLCLTKELAESGQKM--------------------------SYGKPCGSRDCHGVCTCFPEKGARGHPGPIGTQGPAGPEGFTGPTGLSGLKGERGSPGPLGPYGSKGDKGPIGVPGFVGISGIPGHPGQPGPRGPPGPDGCNGTQGAVGFPGPDGYPGILGPPGLPGHKGAKGEP----VPFQGSIT-GIRGDPGLPGLDGIPGPSGSSGSPGDAGPIGPPG-----LQGPPGLPGLPGPE-------------------GNMGLGFQG------EKGVKGDVGLPGPAGPPPS-----TGELEFMGFPKGKKGSKGEPGPPGFPGMSGPPG-VPEFGSTGEKGE---KGILGLPGPRGPMGSEGIQGHPGRQGKKGTSGF-PGINGFPGIKGEKGDIGVRGPDSFTDADGAV----ISGYPGDPGVLGLPGLRGDEGVQGQRGPSGTPGLPS-LTGLP-GALGPQGFPGLKGDQGNSGR---TTFGEAGLPGRVGLPGLPGLPGPSGPPGRTFETGHLSNIEPGFPGLQGEQGPKGHQGLKGVKGDSGFC-----------ACE-GGAPNIGPHGEPGLPGIQGPIGLQGFKGTKGDPGSRGASGPAGTPGLFGPRGQTGLKGKKGEPTVSR---GSKMSGDKGDPGPQGTPGLAGTPGKDGRPGLPGLPGIQG-DGGSGFPGERGLPGLPGEKGHDGPIGPPGIGLPGPPGPRGLPGDKGVDGLPGQQGLRGAQG-----------------VTLPCIIPG-SYGPSGFPGAPGFPGSKGARGLPGIPG------KPGTHGSKGGPGSPGLMHLPGLPGFPGVRGEKGLPGFPGLPGKDGYPGKAGSPGLPGFKGAAGDIFGAENGASGEQGLQGLPGDKGFPGDSGLPGPKGLNGKPGMLGPKGERGNPGTSGPPGQPGPSGSTDPFGIKGTSGFPGAPGLPGISGHPGKKGQRGDIGQPGSTGKRGLPGIKGLPGPQGSPGFLGSPGLSGVTGLPGIEGQKGEKGSSGPVGFPGLPGLPGLPGAD---GLKGFSGSFGKVGQPGQTGTSGEKGDRGDPGPVG--ISSPRPPMLNLWFKGEKGSRGSAGSDGFPGPRGDKGEPGIPGLPGPPGATGQTNTIKGLNGRPGSPGSMGRRGLPGLKGSLGIAGFPGMPGKSGSQGLTGTSGLLGATGIPGLKGDQGQT-LGISGSPGPKGQPGELGFKGVKGKDGLVGDRGYPGNKGDGGKVGITGDPGFPGSPGLQG-ISGMNGDPGLPGSSGHLGSIGRPGPSGLIGPKGFPGAPGLHGLNGLPGTKGTHGTPGAS-ITGVPGPAGLPGP--KGERGVPGI--VIGDPGKQGSKGQKGDQGSPGLQGPAGTPGAPGISLPSVIAGQPGDPGRPGLDGERGRPGPPGPPGPPGPSSDQGDPGDSGFPGIPGLQGFKGNQGLPGFSGLSGELGLKGMRGEPGLMGTPGKIGQPGDPGFPGMKGKAGPRGFSGPQGAPGHTPIA-EAMQVPPGPLGLPGIDGIPGLIGDPGSQGSVGLQGSKGLPGIPGKDGPSGLPGPSGILGDPGLPGLQGPPGFEGAPGNQGPIGQPGMPG-HGVRVGYTLVKHSQSEQVPLCPTGMSRLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIP--MMPVGQTQIPQYISRCSVCEAPSQAIAVHSQDIIVPQCPLGWHSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERGQFREEPVSETLKTGQLH-TRVSRCQVCMKTP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6Z091-1", "uniprot_id": "A0A8M6Z091_DANRE", "id": "A0A8M6Z091-1", "name": "", "aln": "--------------MRLWSFV----LPFVLYAVSAQGGS----------------------------TLQEPCAGRDCSGPCPCFPLKGGRGQPGELGPVGSGGPEGFYGGPGPVGPKAEQGHIGRKGPPGQNGDKGPMGVPGYPGNDGVPGHPGQEGPRGPPGLDGCNGTQGDTGYSGLDGYSGIPGSPGFPGLKGQKGEPSYLNIPSQNILTQGPPGPQGYPGPIGPRGPDGFDGLPGLPGPPGPPGSPGQGYKGEPGEKGDVGPQGV----------------RGNPSVQFNAPAISTINKGEKGDVGPPGDPGHPLV-----NGVVEFVGIPKADKGIQGDKGYAGNPGLPGRQGPVNPFRYPGEVGE---KGILGLPGGRGPPGLNGPPGLPGRKGFTGSEGF-PGQPGLNGPKGDIGDPGPPGP--IVDSPVFE----IKGSKGDRGFPGYPGFPGDTGYGGLPGQPGAPGPPAFFTGRP-GAPGFPGSRGPKGQRGNPGR---DSYGSEGLPGSQGLSGPP---GLPGPPG--TSSNFIVTPLPGFPGQPGPRGPFGSQGIKGFKGENGDC-----------NCL-GGG-TIGAQGPPGPPGFPGFIGLNGLKGEIGDNGYQGLPGPQGPQGRRGDRGFNGRKGEKGNAFFPQ---GKGQKGDLGQQGPPGPLGFSNSPGRDGSPGFPGQPGLPG-EPGFGLTGDKGFPGIPGSKGRPGASGEPGIGYPGVAGFKGMQGEPGFNGLPGPPGPPGSKGDSCRQAGLIDASLEEGGTPLPCRLPG-IQGDKGFPGRPGVPGPKGRVGSAGLNG------RPGFDGSKGERGEPGSGGRPGPQGFPGPRGDAGLPGTTNI-GLQGSPGRDGFPGSPGPKGEPGAVLGATPGDLGRQGRPGEPGDKGQPGVPGFPGNPGVDGRNGFPGIKGERGVNGLPGPVGPIGPPGELPQGGIPGPRGPPGAKGFDGPPGFPGLKGMRGDPGPPGPGGIKGIQGIPGIPGSQGFRGPPGPTGFTERDGIPGRPGIKGEKGSLGLLGFQGLPGSPGIPGGP---GIKGLPGFRGQDGLIGRDGPRGPRGDRGEPGPPG--PSTPPIPVERL-VKGEPGEPGIVGGPGFTGQRGDKGFPGPPGRPGFPGPPGFADQAKGLPGQPGIPGVPGSSGFPGPKGFPGVMGFPGFSGVKGDNGVPGVPGFPGAQGPPGAKGEKGDS-YASSGPTGPKGNIGNSGFPGGPGRPGEPGDSGFPGVLGYQGQKGFPGDPGIPGFVGSSG-PPGPRGLPGYPGLRGRDGDPGRPGGPGLPGDKGFPGSPGLDGLNGLPGSRGPPGVPGVI-EGGRVGPPGVNGQ--KGERGTS----QPGVPGRPGEKGVRGDTGARGLRGYPGNPGPPGQPSLSNIPGPLGDPGLPGLDGREGPFGPPGLPGPPGPGTVQGDRGDPGFPGRPGIIGPRGEPGGFGAPGLQGNPGFKGQRGEPGFSGVPGRPGSPGEPGDYGRSGPRGLKGTSGPVGNPGFVFASNITARMPSGDPGQPGLDGFAGQPGIPGLPGSPGNPGPKGFRGQVGRLGPVGLAGSPGFTGDPGPSGIQGPTGLQGPRGKPGLPGIPAPPT-RSTGIGYTLVKHSQSTRVPMCPEGMTRLWEGYSLLYVEGQEKAHNQDLGLPGSCLPHFSTIPFLYCTANEICYYASRNDKSYWLSTTAAIP--MMPVANQEISPYISRCSVCEVPSQPIAVHSQDLTIPTCPQGWRSLWIGYSFLMHTGAGGEGGGQSLMSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTVDVNEQFVQGPTQETLKGDQFR-SRLSRCQVCMKIL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53420-1", "uniprot_id": "CO4A4_HUMAN", "id": "P53420-1", "name": "Collagen alpha-4(IV) chain", "aln": "MWSLHIVLMRCSFRLTKSLATGPWSLILILFSVQYVYGSGK--------------------------KYIGPCGGRDCS-VCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNS-----VFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLV-----GPPGQPGRPGLK-------------------GNPGVGVKG------QMGDPGEVGQQGSPGPTLL------VEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKG----ESGIGAKGE---KGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGD-PGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP----LKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGR---PDS-APGKPGKPGSPGLPGAPGLQGLPGS--SVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLC-----------ACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSR---VKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPG-DHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKG-----------------DTISCNVTY--PGRHGPPGFDGPPGPKGFPGPQGAPG------LSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS-SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP---GAKGEP---GEKGMSGLPGDRGLRGAKGAIGPPG-----DEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDP-ASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHG-MPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLH-DVGPPGPVGIPGL--KGERGDPGSP-GISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPD--PGPPGDQGPPGPDGPRGAPGPPGLPG--SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPG-PPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFG--PGYLGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLASAAPLP--MMPLSEEAIRPYVSRCAVCEAPAQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFLECQGRQGTCHFFANKYSFWLTTVKADLQFSSAPAPDTLKESQAQRQKISRCQVCVKYS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02462-1", "uniprot_id": "CO4A1_HUMAN", "id": "P02462-1", "name": "Collagen alpha-1(IV) chain", "aln": "------------MGPRLSVWL----LLLPAALLLHEEHSRA--------------------------AAKGGCAGSGCG-KCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPG---EILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPP-----GPPGPPGPPGEK-------------------GQMGLSFQG------PKGDKGDQGVSGPPGVPGQ-----AQVQE--------KGDFATKGEKGQKGEPGFQG-------MPGVGE---KGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGY-PGLIGRQGPQGEKGEAGPPGPPGIVIGTGP------LGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGT---SLP---GPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGES-----------CLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLR--LKGDKGDPGFPGQPGMPGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG-------------------KIVPLPG-PPGAEGLPGSPGFPGPQGDRGFPGTPG------RPGLPGEKGAVGQPG-IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP-GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLP---GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPG-----SMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQP-GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPG-LPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLP-GRGFPGFPGAKGD--KGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPG----HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPP-GPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHG-RGTCNYYANAYSFWLATIERSE-MFKKPTPSTLKAGELR-THVSRCQVCMRRT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MA59-1", "uniprot_id": "F1MA59_RAT", "id": "F1MA59-1", "name": "", "aln": "------------MGPRLSVWL----LLPLAALLLHEERSRA--------------------------AAKGDCGGSGCG-KCDCHGVKGQKGERGFPGLQGVIGFPGMQGPEGPHGPPGQKGDAGEPGLPGTKGTRGPPGAAGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFSGNPGPPGLPGMKGDPG---EILGHVPGTLLKGERGFPGIPGAPGSPGLPGLQGPVGPPGFTGPP-----GPPGPPGPPGEK-------------------GQMGSSFQG------PKGDKGEQGVSGPPGVPGQ-----AQVKE--------KGDFAPTGEKGQKGEPGFQG-------TPGYGE---KGEPGKPGPRGKPGKDGEKGEKGSPGFPGESGY-PGLPGRQGPQGEKGEPGLPGPPGTVVGTRP------LGEKGERGYPGSPGLRGEPGPKGYPGSPGQPGPPGFAVPGQTGAPGFPGERGEKGERGSPGV---SLP---GPSGRDGAPGPPGPPGPPGQPGHTNGIVECQPGPPGDQGPPGIPGQPGLTGEVGQKGQKGES-----------CLACDTEGLRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGLEGLPGPQGSPGLIGQPGAKGEPGEIFFDMR--LKGDKGDPGFPGQPGMPGRAGTPGRDGHPGLPGPKGSPGSIGLKGERGPPGGVGFPGSRGDIGPPGPPGVGPIGPIGEKGQAGLPGGPGSPGLPGPKGEAG-------------------KVVPLPG-PPGAAGLPGSPGFPGPQGDRGFPGTPG------RPGNPGEKGAVGQPG-IGFPGLPGPKGVDGLPGEIGRPGSPGRPGFNGLPGNPGPQGQKGEPGIGLPGLKGQPGLPGIPGTPGEKGSIGGPGVPGEQGLTGPPGLQGIRGDPGPPGVQGPAGPPGVPG-IGPPGAMGPPGGQGPPGSSGPPGVKGEKGFPGFPGLDMP-GPKGDKGSQGLPGLTGQSGLPGLPGQQGTPGVPGFPGSKGEMGVMGTPGQPGSPGPAGAPGLP---GEKGDHGFPGSSGPRGDPGFKGDKGDVGLPGMPG-----SMEHVDMGSMKGQKGDQGEKGQIGPTGDKGSRGDPGTPGVPGKDGQAGHPGQP-GPKGDPGLSGIPGSPGLPGPKGSVGGMGLPGSPGEKGVPGIPGSQGVPGSPGEKGAKGEKGQSGLPGIGIPGRPGDKGDQGLAGFPGSPGEKGEKGSAGTPGMPGSPGPRGSPGNIGHPGSPG-LPGEKGDKGLPGLDGVPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEQGLP-GRGFPGFPGTKGD--KGSKGEVGFPGLAGSPGIPGAKGEQGFMGPPGPQGQPGLPGTPG----HPVEGPKGDRGPQGQPGLPGHPGPMGPPGFPGIDGPKGDKGNPGWPGAPGAPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGQKGLPGLQGVKGDQGDQGIPGPKGLQGPPGPP-GPYDVIKGEPGLPGPEGPPGLKGLQGPPGPKGQQGVTGSVGLPGPPGVPGFDGAPGQKGETGPFGPPGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTTDDPLCPPGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPISGDNIRPFISRCAVCEAPAMVMAVHSQTIQIPQCPNGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHG-RGTCNYYANAYSFWLATIERSE-MFKKPTPSTLKAGELR-THVSRCQVCMRRT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7UT91-1", "uniprot_id": "A0A8N7UT91_DANRE", "id": "A0A8N7UT91-1", "name": "", "aln": "--------------MRLPCVT----VFLLAVFLSIDEST-----------------------------AKGGCSGSSCG-GCDCSGVKGAKGEVGLPGLMGLVGFPGMQGHEGPPGSMGPKGDRGEIGAPGIKGSRGLPGQAGFPGRPGIPGLPGLEGAPGPQGIPGCNGTKGERGFDGIPGITGLLGPPGIPGIKGGKGDPG---GVIG-LP-IPLKGDRGLPGQHGFPGQKGNAGQQGPVGPPGPYGPP-----GRPGDPGQKGEP-------------------GDK-LTFIG------EKGEKGQRGLTGPPGPPGR-----SEEYEGPATTLYLPGPPGETGSTGDKGDKGSCA-------PHQHGI---KGEPGPPGPIGKPGKDGQSGEKGEIGFPGNPGL-DGFKG------DKGERGPPGYG-----------------AGSPGPPGPPGLPGAEGETGFQGEPGAPGPPGRYIEGPPGPPGFPGEIGKKGEKGADGR---SFP---GPKGTDGQPGPPGPPGPINEECDVT------------KGAPGPPGPPGLQGEVGQKGDQGET-----------CTECNAFGPPGLPGPQGPKGLQGFPGPAGIKGEKGLPGPSGPAGNAGFNGAPGLMGKPGAQGEPGDIFVAPG--LKGDKGLPGTTGDRGFPGVDGLPGKDGRPGYPGTKGEPAKFGIKGDRGPDGDFGVPGPPGERGPPGEPGIGRPGQPGDKGSAGFPGAPGRPGLQGAKGEAG-------------------KVISLPG-PQGAPGPRGESGRPGLQGDRGFPGERG------VPGFPGDKGDPGLPG-IGLPGPPGPKGYSGIPGPSGIPGESGEPGQDGLPGRAGTPGQKGEPGRGLPGPKGTTGLPGVPGFPGEKGNTGMPGVPGTEGRTGPPGPQGLKGNPGPPGVHGALGPPGPPG-LGEPGAPGPMGPPGGPGPIGQSGIKGDKGYQGLPGLDMP-GPPGDRGSPGVPGLPGSKGLPGQPGVPGKDGFPGERGPKGEIGIMGMAGPPGFQGLVGNPGDP---GQKGDPGMPGIRGDFGDLGTKGERGEPGLQGPPG-----NMSDVDMEHMKGDKGDIGDRGDPGPTGEKGFPGTSGDPGMPGKDGMPGSPGQP-GDKGDPGIIGKPGSIGEPGDTGARGDMGYPGSMGPKGAKGVGGSPGHPGFKGTDGSKGDKGDPGEPGIGIPGPPGTKGNIGSPGFPGEPGEKGQKGTMGMTGTPGTQGHKGDQGSIGYPGSPG-KPGEKGVGGLPGSPGEPGTPGRPGEPGLQGPPGPHGEKGQSGQDGIPGFTGERGEPGVP-GRGLPGSRGEPGG--KGDKGNPGLPGIPGSPGIPGTKGDKGLSGLPGDQGRPGERGLPG----QAMEGPKGDRGDQGQPGERGATGEQGPPGIPGSAGSKGEKGDVGFQGAPGSRGYKGDKGFIGVSGEPGLPGYNGPKGEMGPQGVPGFPGTKGEQGVIGSKGEGGDRGFPGLKGSEGPPGPP-GPHTYVKGDPGPPGPQGPQGLVGIQGFPGAKGQQGVMGLQGLKGSDGTPGYNGHPGAKGEPGQTGPPGPRGYPGPPGPDGIPGHIGPPGPSSMDHGFLVTRHSQTIDVPHCPQGTTPIYDGYSLLYVQGNERSHGQDLGTAGSCLRKFSPMPFLFCNINNVCNFASRNDYSYWLTTPEPMPMSMAPVTGESIKPFISRCAVCEAPAMVIAVHSQTIQIPNCPDGWASLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHG-RGTCNYYANSYSFWLATIEDTD-MFTKPVPATLKAGSLR-THISRCQVCMKRV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08120-1", "uniprot_id": "CO4A1_DROME", "id": "P08120-1", "name": "Collagen alpha-1(IV) chain", "aln": "MLPFWKRLLYAAVIAGALVGADAQFWKTAGTAGSIQDSVKHYNRNEPKFPIDDSYDIVDSAGVARGDLPPKNCTAGYAGCVPKCIAEKGNRGLPGPLGPTGLKGEMGFPGMEGPSGDKGQKGDPGPYGQRGDKGERGSPGLHGQAGVPGVQGPAGNPGAPGINGKDGCDGQDGIPGLEGLSGMPGPRGYAGQLGSKGEKGEP----AKENGDYAKGEKGEPGWRGTAGLAGPQGFPGEKGERGDSGPYGAK-----GPRGEHGLKGEKGASCYGPMKPGAPGIKGEKGEPASSFPVKP-THTVMGPRGDMGQKGEPGLVGR---KGEPGPEGDTGLDGQKGEKGLPGGPGDRGRQGNFGPPGSTGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGLLGPPGPPGGGRGTPGPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNEGPPGKKGEKGTAGLNGPKG--SIGPIGHPGPPGPEGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFKGNAGAPGDSKLGRPGTPGAAGAPGQKGDAGRPGTPGQKGDMGIKGDVGGKCSSCRAGPKGDKGTSGLPGIPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLKGDKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQSIKGEPGFHGRDGAKGDKGSFGRSGEKGEPG-----------------SCALDEIKMPAKGNKGEPGQTGMPGPPGEDGSPGERG------YTGLKGNTGPQGPPGVEGPRGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGLNGLQGEKGDRGPTGPIGFPGADGSVGYPGD---RGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGVPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDRGAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDG-----PPGLPGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPG-LAVHGRAGPP-GEKGDQGRSGIDGRDGINGEKGEQGLQGVWGQPGEKGSVGAPGIPGAPGMDGLPGAAG--------APGAVGYPGDRGDKGEPGLSGLPGLKGETGPVGLQGFTGAPGPKGERGIRGQPGLPATVPDIRGDKGSQGERGYTGEKGEQGERGLTGPAGVAGAKGDRGLQGPPGASGLNGIPGAKGDIGPRGEIGYPGVTIKGEKGLPGR---PGRNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGPIGPAGSKGERGLAGSPGQPGQDGFPGAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDRGLQGPSGLPGLVGQKGDTGYPGLNGNDGPVGAPGERGFTGPKGRDGRDGTPGLPGQKGEPGML--PPPGPKGEPGQPGRNGPKGEPGRPGERGLIGIQGERGEKGERGLIGETGNVGRPGPKGDRGEPGERGYEGAIGLIGQKGEPGAPAPAA-LDYLTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPGSCVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIP--MMPVENIEIRQYISRCVVCEAPANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGGGGQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQ-PFERPQQQTIKAGERQ-SHVSRCQVCMKNSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * ** :* * * * * * * * * . :* * * * :* * * * * *: * .* *. * * * :* * * * * * * * * * **:. * * * * * * * * * * * * * * *: . * *: * * * * . * * * . .* * .* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * . * * * * * * **: * * * * * * * * * * * * * * * * * * *. . * * * * * . * :* * * * . . * * * * * * * ** . * * * * * * * * * . * * * ** * * * * * * * * .* * * * * * . . * * * * * :* * . * * * * * * * * ** * * * :* * * * * * * * * * * * * * * :* * * * * * * * * * * *. . * ** * * * * * * * * ** * * * * * :* * * * * *. * * * * * * .* * * . * .. * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * . . * * * * * * * * * * * * * .* * * * * * * * * *. * . * * * * * * * * * * *: * * * * * * ** . :* *. * * * * * * * .* * * .* * * * * * * * * * * * .* * * * * * * * * * * * * * * * * * . .* * * * * * * * * * . . * :. ***: * *. * :: *****:.:*:: :*.**** .***: *..:*. * ::* :* *** ::**:: .:* * *: * ::*** ***.*: :***** :* ** * .*******:***..* *.**:* *******:**::**:** * :***::: . ***: .: * *:* . ::******:: ", "identical_positions": 480, "similar_positions": 119, "identity": "26.02%" }, { "cls_id": "homologset.agr.FB:FBgn0000303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03059-1", "uniprot_id": "CLAT_MOUSE", "id": "Q03059-1", "name": "Choline O-acetyltransferase", "aln": "------------------------------------------------------------------------------------------------------------MPILEKVPPKMPVQASSCEEV---LDLPKLPVPPLQQTLATYLQCMQHLVPEEQ-FRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSS---PAVIFARQHFQDTNDQLRFAASLISGVLSYKALLDSQSIPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDT-LVAQKSSIMPEPEHVIVACCNQFFVLDVVINFR-RLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGDLSD------------------THRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTGNK----KLVRVDSVSELPAPRRLRWKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAVLASEK---------------------LQLLQRAIQAQTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFILSTSQVPTTMEMFCCYGPVVPNGYGACYNPHAEAITFCISSFHGCKETSSVEFAEAVGASLVDMRDLCSSRQPADSKPPTAKERARGPSQAKQS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32738-1", "uniprot_id": "CLAT_RAT", "id": "P32738-1", "name": "Choline O-acetyltransferase", "aln": "------------------------------------------------------------------------------------------------------------MPILEKAPQKMPVKASSWEE----LDLPKLPVPPLQQTLATYLQCMQHLVPEEQ-FRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSS---PAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDT-LVAQKSSIMPEPEHVIVACCNQFFVLDVVINFR-RLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSD------------------THRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNK----KLVRADSVSELPAPRRLRLKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEK---------------------LQLLQTAMQAHKQYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGNGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSRQPADSKPPAPKEKARGPSQAKQS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28329-1", "uniprot_id": "CLAT_HUMAN", "id": "P28329-1", "name": "Choline O-acetyltransferase", "aln": "MGLRTAKKRGLGGGGKWKREEGGGTRGRREVRPACFLQSGGRGDPGDVGGPAGNPGCSPHPRAATRPPPLPAHTPAHTPEWCGAASAEAAEPRRAGPHLCIPAPGLTKTPILEKVPRKMAAKTPSSEE----SGLPKLPVPPLQQTLATYLQCMRHLVSEEQ-FRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSS---PAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDT-LVAQNSSIMPEPEHVIVACCNQFFVLDVVINFR-RLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSD------------------THRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHVTQSSR----KLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEK---------------------LLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2ZGJ1-1", "uniprot_id": "CLAT_DANRE", "id": "B2ZGJ1-1", "name": "Choline O-acetyltransferase", "aln": "------------------------------------------------------------------------------------------------------------MPVSKRE------QSKDTGDP---CALPKLPIPPLKQTLDMYLTCMGHLVPEDQ-FRKTKAVVEKFGAPGGVGETLQKKLLERSEQKANWVYDYWLEDMYLNNRLALPVNSS---PVMVFHKQNFKGQSDVLRFAANLISGVLEYKALIDGRALPVEHARGQLAGTPLCMDQYNKVFTSYRLPGTKTDT-LVAQKSTVMPEPEHIIVACKNQFFVLDVMVNFR-RLNEKDLYTQLERIRKMADIEEERQPPIGLLTSDGRTQWAEARNILIKDSTNRDSLDMIERCLCLVCLDEETATELND------------------SNRALLMLHGGGTDKNGGNRWYDKPMQFVIGADGCCGVVCEHSPFEGIVLVQCSEYLLRYMRGSPS----KLVRAASMSELPAPRRLRWKCSPDIQTFLSASADRLQKLVKNLDMNVHKFTGYGKEFIKRQKMSPDAYVQVALQFTFYRCHGRLVPTYESASIRRFQEGRVDNIRSSTPEALAFVKAMASG-SKITDAEK---------------------MELLWTAIKAQTNYTILAITGMAIDNHLLGLREIAKELKLEKPELFSDTTYATSIHFTLSTSQVPTTEEMFCCYGPVVPNGYGACYNPQTDHILFCVSSFRECAETSSDLFVKTLEGCLKEMQDLCRKCN-TEVKPADSTQRMEGNPKVMKNGSKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07668-1", "uniprot_id": "CLAT_DROME", "id": "P07668-1", "name": "Choline O-acetyltransferase", "aln": "------------------------------------MASNEASTSAAGSGPESAALFSKLRSFSIGSGPNSPQRVVSNLRGFLTHRLSNITPSDTG-----------WKDSILSIPKKWLSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQ-LERTKELIRQFSAPQGIGARLHQYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSN---PGMVFPPRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLPAKPVPVGLLTAEPRSTWARDREMLQEDERNQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHPD----EDNGLP-QHHLPPPERLEWHVGPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVATYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQVACSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLLQN----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32796-1", "uniprot_id": "CACP_YEAST", "id": "P32796-1", "name": "Carnitine O-acetyltransferase, mitochondrial", "aln": "---------------------------------MRICHSRTLSNLKDLPITSRRAMHSAIVNYSTQKAQFPVETNNGEHYWAE-------------------------KPNKFYQNKRPNFQGITFAKQ---QDLPSLPVPELKSTLDKYLQTIRPFCNDVETFERQQLLCKDFSEH--MGPILQDRLKEYANDKRNWMAKFWDEQSYLQYNDPIVPYVSYFYSHMPLPNHLSKIDNDPLIKATAIISTVVKFIEAIKDESLPVEIIKG----MPFCMNSFSLMFNTSRLPGKPEDN-QDTNIFYSVYENNFVTIAYKGKFYKLMTHDGNDKPLSENEIWRQLYSVVFQGSQSDPKLGGIGSLTSLPRDQWREVHLELMKDPISQDSLETIHKSSFMLCLDLDQSPVTLE-------------------EKSRNCWHG-----DGINRFYDKSLQFLVTGNGSSGFLAEHSKMDGTPTLFLNNYVCQQLNKLDVDDFMRKVITPSSTVAMKPMELPFIITPKIHKAIESAQLQFKETIGEHDLRVWHYNKYGKTFIKRHGMSPDAFIQQVIQLAVFKYLKRQLPTYEAASTRKYFKGRTETGRSVSTASLEFVSKWQNGDVPIAEKIQ-----------------------ALKHSAKEHSTYLKNAANGNGVDRHFFGLKNMLKSNDDQIPPLFKDPLFNYSSTWLISTSQLSSEYFDGYGWSQVNDNGFGLAYMLNNEWLHINIVNKPAKSGASVNRLHYYLSQAADEIFDALENENKRKAKL--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **.:*:* *..*: *: : : : :.: : : . *. :* *:. * : : ** :* :: *:: . .: . . : : : * *: ::. ::.. :.. :* : . *:** .: :: : * ** *. .. * ..: : .::: : . *.* :: *: : . : :* **: * * . : * :* .: .*: *. . ::*** . : ** :. **::**.:*::: :* *. *** :* : : : : : . * .* *. : : : ... : : *: * :: *** *** *** ::* .:*:: :: * :.***:** *:: .**.: *: :. :* :. . . : : :. * .:* ::.*:: : :* * : * : :****:. :. * .* * .* : : : : : :* : . : * ", "identical_positions": 97, "similar_positions": 177, "identity": "12.05%" }, { "cls_id": "homologset.agr.FB:FBgn0000307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJF6-1", "uniprot_id": "A0A096MJF6_RAT", "id": "A0A096MJF6-1", "name": "Protein DBF4 homolog A", "aln": "-------MNLETMRIHSKAPLPGGIQDKNEKNRPSLKSLKADNRLEK----SKYKPLWGKIFYLDLPSITICEKLQKDIKELGGRVEEFLSKDISYLVSNKKEAKYAQT----LGRVSPVPSPESAYTAETTSPHPSHDGSSFKSQDRVCLSRGKLLAEKAVKDHDFIP------ANSILSNALSWGVKILHIDDIRYYIEQKKKALGALKKPNTSGRDSGKKAGTGIQKARTGRLKKPFLKVEDVNRTYKPFYLQLPS---MPCINYFLQKPCSPFDIDKSSSMQKHTQPKLKI---------NTDGDKYG-TPAQVQLKEK--------------------RKKGYCECCLQKYEDLETHLLSEKHRNFAQSNQ-YQVVDDIVS----------------KLIFDFVEYERDTPKKKRIRYSVGSLSSVSASVLQNTEPREKLLLEPSFQKDGEESNGQLLEQNL--QCEETQKPEEKHVFGSEPTTYSSTGFKGCVGKP---VSLINAS----EPDLKPDCEQLPLRDNKQEGMRVGS-------------------EHKITVDRKDVDQRGGVTPCVPQSC---TYFSTDSNLPQPKLTADITQFSAQDLQEKDLH-VIGHDSELV------------------------TLNSSREQLTVKARPPPCSP-QEPHE--------------------------------GHSEHMESLPCGKIQRKVRMLLGQ-KKANVEPGAEWDKN-----------------------------RTEYLPAHGDRTCGSPVQSLLDLFQTS-------------------GEKSEFLGFTSYTENSGICDVLDIWEEDNSSSLLSTFFSSPSTSAFVGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ41-1", "uniprot_id": "DBF4A_MOUSE", "id": "Q9QZ41-1", "name": "Protein DBF4 homolog A", "aln": "-------MNLETMRIHSKAPLPGGIQDRNEKNRPSLKSLKADNRLEK----SKYKPLWGKIFYLDLPSITICEKLQKDIKELGGRVEEFLSKDISYFVSNKKEAKYAQT----LGRVSPVPSPESAYTAETTSPHPSHDGSSFKSQDRVCLSRGKLLAEKAVKDHDFIP------ANSILSNALSWGVKILHIDDIRYYIEQKKKALSALKKSSASGKDAGKKAGPGIQKTRTGRLKKPFLKVEDVNRCYRPFYLQLPS---LPCINYFLQKPCSPFDIEKSSSVQKQAQPKLRI---------NMDGDKCG-TPVQLQLKEK--------------------RKKGYCECCLQKYEDLETHLLSEKHRNFAQSNQ-YQVVDDIVS----------------QLVFDFVEYGRDTPQKKRIRYSVGSLSSVSANVLKNTAPKEKPLLEPNFQKDVGESSGHLLKPNS--QYEETQKPEEKHGFASEPTTYSSAGLKGCDRKP---VSMFNAS----EPDPEQEYAQLPLRDSTP--------------------------EHQVTEGRNDGEQRVDPAPGVSQSCGQVSHLSTESNLPQPQLAADITQLSAKDLQEKGFHVVIGHASDLV------------------------ALNTSKEQLTMKARTPPCSP-QEPHE--------------------------------CDTENMENLPCGKIQRKVRMLLGQ-QKANAEPSAELDKK-----------------------------RTEYLPAHEDRTCGSPVQSLLDLFQTS-------------------EEKSEFLGFTGYTENSGICDVLDIWEEENSSTLLSTFFSSPSTSAFVGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBU7-1", "uniprot_id": "DBF4A_HUMAN", "id": "Q9UBU7-1", "name": "Protein DBF4 homolog A", "aln": "-------MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEK----SKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQT----LGRISPVPSPESAYTAETTSPHPSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIP------SNSILSNALSWGVKILHIDDIRYYIEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTN---MPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRI---------QTDGDKYGGTSIQLQLKEK--------------------KKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQ-YQVVDDIVS----------------KLVFDFVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNF--LYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTA----EDDIRQNFTQLPLHKNKQECILDIS-------------------EHTLSEN-DLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLI------------------------TINSSQEHLTVQAKAPFHTPPEEPNE--------------------------------CDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDK------------------------------RTEFITQEENRICSSPVQSLLDLFQTS-------------------EEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLTAFFSSPSTSTFTGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NFT6-1", "uniprot_id": "DBF4B_HUMAN", "id": "Q8NFT6-1", "name": "Protein DBF4 homolog B", "aln": "--------MSEPGKGDDCLELESSMAESRLR-APDLGVSRCLGKCQKNSPGARKHPFSGKSFYLDLPAGKNLQFLTGAIQQLGGVIEGFLSKEVSYIVSSRREVKAESSGKSHRGCPSPSPSEVRVETSAMVDPKGSHPRPSRKPVDSVPLSRGKELLQKAIRNQGSISGGGSGGSSSLLTNARSWGVRILHVDEMMMHVQQLSLASLCVKKQQPK-KPEGTCPAAESRTRKVARLKAPFLKIEDESRKFRPFHHQFKS---FPEISFLGPKDASPFEAPTTLGSMHHTRE-------------SKDGEPSP--RSAAHTMPR--------------------RKKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIA----------------QLSHSFADIPFQAGLPRWSGSPASDCDPLCPETLHPHQPSHPRAASPRIRKE--DSCQASVTQGR--AAGQQRWTESLDGVMGPPASHTCVSAT----------TLLPAL----PKGSREQGCLCPCP----------------------------------------------------------------ASFTQSHLVTSLALLPGEWSPAEDMP---LHPSQEN------------------------SFAPADIPVKGPLLFPEARPWLMSAR--------------------------------CWVRPFPFVTWGCLIPHDTTPLHE----EVSP-CPCLRL-----------------------------GYLYLLLTQSLWCRVRVPSLSTAGPIPR------------------TSHPCTLAFPSYLNDHDLGHLCQAKPQ--GWNTPQPFLHCGFLAVDSG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NK54-1", "uniprot_id": "CHIF_DROME", "id": "Q9NK54-1", "name": "Protein chiffon", "aln": "--------MQPQSDKQSASRLATTTSHSTAAASATAATPPKVKVIKS------KRPLCHFKFYLDICDHQLAKRIESDIKALGGHLEFFLSDDITHFVTDKPEVIGGTS-----GTPGTPSTPGTPTSHYQQNDGSARKPNQRQSRADAILSRVRRSTVGVVNSGNSTP-----------TTSLKRSYTIWQTDYAQRFIKRIQTELKQYLEGKKEGGGGSTSASP-----HHIQLKKQYVKIESVKRNYRPYYHLIKQPDDWPKIDLSSEDGAFRLLTKSKTKDKEHSMTRKPLGSRTSQKDKQAAGEAKPLQHPSLQELKKQSAIPNSPRSNCREPIDSSEKQGGVCEICKLEYDILNIHLQSKDHELFAKNSDNFLALDTLIQSSADVNRFLEEEPVESELDMDVDESLSNEELQSPRQRPSPALREKSKRITKGKHSSEKFQGVAVASPQTPFPGAKKVQGNSPGSLSELQRQEHPTTAAATPTTNSGRRKTQNSGLSPPKRAMLPPSSIYKVVETREECATPPRGRGRPPNQVDSPSLIVKFQKIRQTELQRLNGEAENFMFPRTAVPTTRSSSELPTDVDRQTTSDVRGRYSISSASLDTSTSEAETKESSGLPTSIRKRAQAVGRRRKVGGAAAQDVFQRQLSTGSSSSNSNQQRFPSAPIQPEEGPQPQPKPQLKIKIKQEQLVATRKSSRTATAIVTAATASSHQQQQLRQTTCRKMANKLEDRMGELVKPKIKIKKEVIEEQKVKELEDLEEILDKELDEEVDSSCSSGSDEDYIAGSQRRITAAPRKSTDTREQRAARRLSRLTINRSAGELELTEVKTSPSKSRTKIQKPSSPTKNKVKQTKAVPPAIDLFFDCSKSERLREMQYTFESLPSGELWNRVFLRQDAGEENYYTYYGSTNYRKLPYEMGPIPMAKTLPAHSCALCREASEVKQDKGEQIKLEDQKPAPKKEVKKEEEVQSSSSSATYKNKKLHLLQRYQQEQEQLQQLEGNSLATAGAKCDSKASTPELLEREFASGSMGDRVQLIERVRSTSSSSCSNSQRSGITCRNKQLARIAELPPRKSPREHASTLALVSCIIRQRQDSQSKTNSEAEEPPPPVAAPKLKTPIKQEPVAPSSPRTTRSQAATPVEELRFATEISETVKRMRRGQNKYDHSPPAPVPTPATSSPVRSRRLTPAARNQSQIYSRRLEFATSQRESSASALLGKRKRRVNPSVAGTVRPTTQNLPGTGAYRGVRKLPSKKGLLEYEMETCALKALDQARQYCNPGFVAWQLDKYLELAGKEYDIEFDQISPEVESEGREERLVNTPQTPPPTDCFTSEFDLCDLIMGSAGSGDDDEDVSRGNPPGSGRRMSNLNLYASYYRKRKSLKSNRTGWPKAQRRRNAGGLGGSRALPDERINFQKMGLAELHPIKQEPMETEEEQTTTTTTTTTTSATRGNLLSKDDEDDEGGGNSPSGGSPADDKQNSREDAVMTPPATDVDEQAEPQADEMESLPDEDETMADSVDQQQDVEAEIEATDADVEEEEEEEDEDEDVFEDAYEEQDMGIQKTEPHEKRARIPSISVTTPPEDSSQGKKLLLTLHNGQRLQATSTPSTGQVQQHQRRTPQLNGSLGSCISPSEKLGDNSDIFTVSSDGLDTDLDLSNTQAGDSHEHCPHQTTPKRKFDISKYAPPNSGKAASSCAAEAATAAVKSLAISQFLKKETCASSSSMRNAWRRTQRRAISAACISAAPSARVPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32325-1", "uniprot_id": "DBF4_YEAST", "id": "P32325-1", "name": "DDK kinase regulatory subunit DBF4", "aln": "MVSPTKMIIRSPLKETDTNLKHNNGIAASTTAAGHLNVFSNDNNCNNNN-TTESFPKKRSLERLELQQQQHLHEKKRARIERARSIEGAVQVSKGTGLKNVEPRVTPKELLEWQTNWKKIMKRDSRIYFDITDDVEMNTYNKSKMDKRRDLLKRGFLTLGAQITQFFDTT-----VTIVITRRSVENIYLLKDTDILSRAKKNYMKVWSYEKAARFLKNLDVDLDHLSKTKSASLAAPTLSNLLHNEKLYGPTDRDPRTK--RDDIHYFKYPHVYLYDLWQTWAPIITLEWKPQE---------LTNLDELPYPILKIGSFGR----------------CPFIGDRNYDESSYKRVVKRYSRDKANKKYALQLRALFQYHADTLLNTSSVN---------DQTKNLIFIPHTCNDSTKSFKKWMQEKAKNFEKTELKKTDDSAVQDVRNEHADQTDEKNSILLNETETKEPPLKEEKENKQSIAEESNKYPQRKELAATPKLN--HPVLATFARQETEEVPDDLCTLKTKSRQAFEIKASG-----------------AHQSNDVATSFGNGLGPTRASVMSKNMKSLSRLMVDRKLGVKQTNGNNKNYTATIATTAETSKENRHRLDFN--------------------------ALKKDEAPSKETGKDSAVHLETNR---------------------------------KPQNFPKVATKSVSADSKVHNDIKITTTESPTASKKST-----------------------------STNVTLHFNAQTAQTAQPVKKETVKNSG------------------YCENCRVKYESLEQHIVSEKHLSFAENDLNFEAIDSLIENLRFQI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. * *:: . . :* :. . :.. . . . . : * : . . : . : : :: : . :: .: : * * : : . . * . : : .: : * :: . : : : . * . . .:: . : . . : . . : . : . . . . :. . :: ", "identical_positions": 9, "similar_positions": 76, "identity": "0.52%" }, { "cls_id": "homologset.agr.FB:FBgn0000308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07274-1", "uniprot_id": "PROF_YEAST", "id": "P07274-1", "name": "Profilin", "aln": "-MSWQAYTDN-LIGTGKVDKAVIYSRAGDAVWATSGGLSLQPNEIGEIVQGFDNPAGLQS-NGLHIQGQKFMLLRADDRSIYGRHDAEGVVCVRTKQTVIIAHYPPTVQAGEATKIVEQLADYLIGVQY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25843-1", "uniprot_id": "PROF_DROME", "id": "P25843-1", "name": "Profilin", "aln": "-MSWQDYVDNQLLASQCVTKACIAGHDGN-IWAQSSGFEVTKEELSKLISGFDQQDGLTS-NGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYLITCGY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8NHR9-1", "uniprot_id": "PROF4_HUMAN", "id": "Q8NHR9-1", "name": "Profilin-4", "aln": "MSHLQSLLLDTLLGTKHVDSAALIKIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D6I3-1", "uniprot_id": "PROF4_MOUSE", "id": "Q9D6I3-1", "name": "Profilin-4", "aln": "MSHLQNLLLDTLLGTKHVDSAALIKLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGEYLRKKGN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *:.: * .* : : . * *:.: .:: ::.** : :*: : : : : . : : .: ** ::* :::: * : . ... .*.*.:** ", "identical_positions": 17, "similar_positions": 44, "identity": "13.18%" }, { "cls_id": "homologset.agr.FB:FBgn0000316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03555-1", "uniprot_id": "GEPH_RAT", "id": "Q03555-1", "name": "Gephyrin", "aln": "MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPFCGLQKGATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAALAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQ-------------------IRRPDESKGVASRVGSLK----------------------VQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG----------------------------------NPVSAVVTCNLFVVPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUV3-1", "uniprot_id": "GEPH_MOUSE", "id": "Q8BUV3-1", "name": "Gephyrin", "aln": "MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAALAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQ-------------------IRRPDESKGVASRVGSLKARLPSCSSTYS--------VSEVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG----------------------------------NPVSAVVTCNLFVVPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQX3-1", "uniprot_id": "GEPH_HUMAN", "id": "Q9NQX3-1", "name": "Gephyrin", "aln": "MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPK------------------------------------------------------------VQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG----------------------------------NPVSAVVTCNLFVVPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PSF7-1", "uniprot_id": "A0A8M9PSF7_DANRE", "id": "A0A8M9PSF7-1", "name": "Gephyrin", "aln": "MASDGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGVNLKDLVHDPSLLGGTISAYKIVPDEIDEIKETLVDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIEREAPGMSLAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLREAVVKVKEIPNELEDLPSPPPPLSPLPASSPHRQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAASIAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKARLPSSSSTLSIAEASRREFRAHLDEVITLKSRFSTLDQLQCRLEVLKDDRRGHRTFSSRVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTAVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-THTVMPGQVMRVTTGAPIPCGADAVVQVEDTELLRESEDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVQKFPVIAVMSTGNELLNPEDDLHPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGINRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDMDGSRKLIFALPGRD-------------------------------GNPVSAVVTCNLFVIPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQVSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PE84-1", "uniprot_id": "A0A8M9PE84_DANRE", "id": "A0A8M9PE84-1", "name": "Gephyrin", "aln": "MASDGMILTNHDHQIRVGILTVSDSCFRNLAEDRSGINLKDLVHDPSLLGGIISAYKIVPDEIDEIKEILVDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATREVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDALEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEDEEKKDSGVASTEDSGSSHITAAAIAAKSMTSHLSHAVVMAKGGQPLSGFIPSTSIPSHFTCSCSDTIPESIISRGVQVLPRDTASLSTTPSESPCAQQ-SRLSTASCPTPKARLTSCSSTYSVTEASRREFRAHLDDVISHKSRYSTLDQLHSRLEGLKDDRRNHRTFDSRVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRGPYTGDLAPLPRKGIWRQNGSSWRKIPLCTGAEAKAERRALANAAHTPKYCTDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TLTVMPGQVMRVTTGAPIPCGADAVVQVEDTELLRESEDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVQKFPVVAVMSTGNELLNPEDDLHPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGARKLIFALPGNFTYRDTGATLLEAVPLSDTEACRMPVPPPPRGSNPVSAVVTCNLFVIPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39205-1", "uniprot_id": "CIN_DROME", "id": "P39205-1", "name": "Molybdenum cofactor synthesis protein cinnamon", "aln": "-----------MESITFGVLTISDTCWQEPEKDTSGPILRQLIGET--FANTQVIGNIVPDEKDIIQQELRKWIDREELRVILTTGGTGFAPRDVTPE-------------ATRQLLEKECPQLSMYITLESIKQTQYAALSRGLCGIAGNTLILNLPGSEKAVKECFQTISALLPHAVHLIGDDVSLVRKTHAEVQGS-------AQKSHICPHKTG----------------TGTDSDRNSP------------------------------------------------------------YPMLP-------------------------------------------------------------------------------------------VQEVLS---IIFNTVQKTANLNKIL--------------------LEMN---------------------------------------------------------------------------APVNIPPFRASIKDGYAMKSTGFSGTKRVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQLDKNG-QESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLILSK--PKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLE-DLQFRIHCGRVNIKPGKPMTFASRKD----KYFFGLPG----------------------------------NPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDFSLDSRPEFVRASVISKSGE--LYASVNGNQISSRLQSIVGADVLINLPARTSDRPLAKAGEIFPASVLRFDFISKYE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* .*:**:**:*::: :* ** *::*: :. :.. :***** : *:: * .* *.:**.:***************** **::::*:*.* ::: : : *:: * . *** :*** *:***:*****:*. :**** * . ****:.*: : : *:: ::. : . .**: :*. * .:* :** **. * *:.: :.:.::.*: ***. * *:*** **:*****::::. .* : ::* **:.* : .: .: ::.****:* **.*******:*:: ..:* :* * ***:.:.* *:**:*:*:. .: ::. .***:** : : * :*::***.** .*.::* **** *** : * : .*: :: ::.*. : ::* * :. .*.:* *******:**::*.**: **: :** *** :*** * ***: . * :*.*** *****.** :**.:**:* * : ::::.:* *..**.***: *. : : * :*. .***:**** *: .*: *: **.:*.: : **:. . *: ", "identical_positions": 231, "similar_positions": 202, "identity": "24.5%" }, { "cls_id": "homologset.agr.FB:FBgn0000317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XYU9-1", "uniprot_id": "A0A8J8XYU9_RAT", "id": "A0A8J8XYU9-1", "name": "", "aln": "MVILQKGDYVWMDLKSGQEFDVPIGAMVKLCESGQIQVVDDEGNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSSEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNNRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQAPDERNYHVFYCMLEGMNEEEKKKLGLGQAADYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEILKLLAAILHMGNLQYEARTFENLDACEVLFSPSLATAASHLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVEKINAAIYKPPSQEVTNSRRSIGLLDIFGFENFTVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQEALDMIANRPMNVISLIDEESKFPKGTDATMLHKLNSQHRLNANYVPPKNSHETQFGINHFAGIVYYESQGFLEKNRDTLHGDIIQLVHSSRNKFVKQIFQADVAM--------------GAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRHAGYPIRYSFVEFVERYRVLLPGVKPAYKQDDLQGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLRLKSAATLIQRHWRGHHCRKNYELIRLGFLRLQALHRSRKLHKQYRLARQRIIKFQARCRAYLVRRAFRHRLWAVITVQAYARGMIARRLHRRLRVEYWRRLEAERMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEEARRKKELLQQMERARHEPINHSDMVDKMFGFLGTSSG--LPGQEGQAPSGFEDLERGRREMVEEDVDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYK-RELQALQGEGE-------------AQLSEGQKKTSVKHKLVHLTLKKKSKLTEEVTKRLHDGESMVQG-NSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKTLLADSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHNPSEDNVATNLIYQQVVRGVKFGEYRCEKEDDLAELASQQYFVDYGSEMILERLLSLVPTYIPDREIT-PLKNLEKWAQLAIAAHKKGIYAQRRTDAQKVKQDVVNYARFKWPLLFSRFYEAYKFSGPPLPKSDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRECRVLLSLGCSDLGCASCHSGRAGLTPAGPCSPCWSCRGAKLMAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIIL-DHDTGEQVMNSGWANGINERTKQRGDFPTDCVYVMPTVTLPPREIVALVTMTPDQRQDVVRLLQLRTAEPEVRTKPYTLEEFSYDYFRSPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKIVGSEELSQEACMSFIAVLKYMGDYPSKRTRSVNELTDQIFEWAVKAEPLKDEAYVQILKQLTDNHIRYSEEKGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIASRLLLKSSEGFSLFVKIADKVISVPENDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGISLIDPRTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRNSRSGR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97479-1", "uniprot_id": "MYO7A_MOUSE", "id": "P97479-1", "name": "Unconventional myosin-VIIa", "aln": "MVILQKGDYVWMDLKSGQEFDVPIGAVVKLCDSGQIQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNNRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQAPDERNYHVFYCMLEGMNEEEKKKLGLGQAADYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHMGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVEKINAAIYKPPPLEVKNSRRSIGLLDIFGFENFTVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQEALDMIANRPMNVISLIDEESKFPKGTDATMLHKLNSQHKLNANYVPPKNSHETQFGINHFAGVVYYESQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAM--------------GAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRHAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLRLKSAATLIQRHWRGHHCRKNYELIRLGFLRLQALHRSRKLHKQYRLARQRIIEFQARCRAYLVRKAFRHRLWAVITVQAYARGMIARRLHRRLRVEYQRRLEAERMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEEARRKKELLEQMEKARHEPINHSDMVDKMFGFLGTSGS--LPGQEGQAPSGFEDLERGRREMVEEDVDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYK-RELQALQGEGE-------------TQLPEGQKKTSVRHKLVHLTLKKKSKLTEEVTKRLNDGESTVQG-NSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKTLLTDSATTARELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHNPSEDNVATNLIYQQVVRGVKFGEYRCEKEDDLAELASQQYFVDYGSEMILERLLSLVPTYIPDREIT-PLKNLEKWAQLAIAAHKKGIYAQRRTDSQKVKEDVVNYARFKWPLLFSRFYEAYKFSGPPLPKSDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRECRVLLSLGCSDLGCATCQSGRAGLTPAGPCSPCWSCRGTKMMAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIIL-DHDTGEQVMNSGWANGINERTKQRGDFPTDCVYVMPTVTLPPREIVALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKILGSEELSQEACMAFVAVLKYMGDYPSKRMRSVNELTDQIFEWALKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIASRLLLKSSEGFSLFVKIADKVISVPENDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPRTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRNSRSGR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13402-1", "uniprot_id": "MYO7A_HUMAN", "id": "Q13402-1", "name": "Unconventional myosin-VIIa", "aln": "MVILQQGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAM--------------GAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGG--LPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYK-RELQALQGEGE-------------AQLPEGQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQG-NSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHGGPPGYAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREIT-PLKTLEKWAQLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRECRVWLSLGCSDLGCAAPHSGWAGLTPAGPCSPCWSCRGAKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIIL-DHDTGEQVMNSGWANGINERTKQRGDFPTDSVYVMPTVTMPPREIVALVTMTPDQRQDVVRLLQLRTAEPEVRAKPYTLEEFSYDYFRPPPKHTLSRVMVSKARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IAZ3-1", "uniprot_id": "A0AC58IAZ3_DANRE", "id": "A0AC58IAZ3-1", "name": "", "aln": "MVILQQGDYVWLDLRTDHEFDVPVGAVVKFCDSGQIQVLDDEGKEQQISLQNATNIKPMHPTSIHGVEDMIRLGDLNEAGILRNLLIRYNDRVIYTYTGSILVAVNPYQLLPIYTPDQIRLYTNKKIGEMPPHIFGIADNCYFSMQRNKKDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYVDIHFNKRGAIEGAKIEQYLLEKSRVCRQAADERNYHIFYCMLAGMSPDQKTKLGLGRATDYTYLTMGNCTVCEGRDDMKEYSSILSAMKILMFTETEYWEISKLLAAILHMGNLRFEARTQRNLDTCVVVRSPDLANAASLLEVDPQDVMMCLTTRTLITRGESVSTPLSVEQGLDVRDAFVKGIYGRLFVWIVDKINATIFRAPSTENRTVRRSIGLLDIFGFENFTVNSFEQLCINFANENLQQFFVHHVFKLEQEEYNLEDINWQDIEFTDNQDALDMIAIKPMNIISLIDEESKFPKGTDATMLNKLNSQHKLNTNYIPPKHSHETQFGIQHFAGVVHYETKGFLEKNRDSLHSDIIQLVHSSKNKFIKQIFQADVAMFLCGYMEPTATLQKGMETRKRSPTLSSQFKRSLELLMRTLSVCQPFFVRCIKPNELKKPMMFDRGLCVRQLRYSGMMETIRIRRAGYPIRYTFAEFVDRYRVLMPGVKPAHKQEDLRGTCQRIVVSVLLRDDDWQIGKTKIFLKDHHDMLLEMERDKVITDKVILIQKTVRGMKERTKFLKVRRAVMLIQRIWRGYITRKHYAVMRVGFLRLQALYRSRKLHQEYQATRIRVTLLQAWCRGLLVRRTFSKRFHAVLTIQAYARGMIARRQCKRLRLERDRRLEAERQRLAEEERLKNQMTARRARAEAARKHQERLAQLDREQEERELAERNETRRKKELLEQMEREKKEPVNDSDMVDKMFGFLGNANS--LPNLEGEAPEGFEDLENAP-KQFKEVIDEPLPLPDDEEEDLSEYKFAKFAATYFQGNATHMYVRRPLKQPLLFHEDEGDQLAALAVWITVLRFMGDLPEPKYHISISDGSEKIPVMTKIYETLGKRTYK-RELQALQVDEEKHEVHSKDTYTLSSSTTDIQKRNSVRHKLVSLTLKKKSKLTEEVTRRLTDSDYSLQG-NSMLEDRPTSNLEKLHFIIGNGILRPALRDEIYCQICKQLSQNASKSSHARGWILLSLCVGCFAPSEKFVKYLRTFINSGPPGYAPYCEERLRRTFANKTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKTLLTDSATTAEELCNALSDKIGLKDRFGFSLYIALFDKVSSLGSGKDHVMDAVSQCEQYAKEQGAQERNAPWRLFFRKEIFTPWHNPAEDGVATNLIYQQIVRGVKFGEYRCDREEDLAELASQQYYVDYGPEILPERLLSLIQSYIPDREIT-PSKTVEKWAQMIIAIHIKGIYTQKRFDSQRVKEEVVDFARFKWPLLFSRFYEAFKFSGPSLPKNDVIVAVNWTGVYFVDEQEQVLLDLSFPEITAVSSSR--------------------------------------GGKLQGQSFTLATIKGDEYTFTSNNAEDIRDLVVAFLEGLRSRSKFVVAMMDSHYPAGQDASFLRFSKGDLIFL-DEHTGEQVLTSGWAHGVNDRTKKRGDFPADNVYVLPTITRPQYDIVSLIIMSPDQRKDSVNLSQQNLLDSGEKVQPYTLEEFSYDHFRPPSKSTLSRVIINKGRGKDKIWCCTREPLKQPLLKKILSHEELSQDACQAFIAILKYMGDYPSKRSRSVNELTDQIFEGALKAEPLKDEIYCQIIKQLTENHVKYSEEKGWELLWLCTGLFPPSNMLLPHVQKFLQSKKHHPVAPDCMQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCRNIAGRMMLHSSEGFSLFVKISDKVISVPEGDFFFDFVRHLTDWIKKARAVKDGTVPSLTYQVFFMKKLWTNTFPGKDPMADSIFHYFQELPKYLRGYHKCSVEEAFQLAALIYRVRFEEDKSHFVHFSKMQKELLPQDLIHQLSPDDWKRSVVTHFNKHAGKSREEAKLMFLEIIYKWPTFGSAFFEVKQSSDPHFPEVLLIAINKLGVTLIDPKTKDILGTHPFTKISNWSSGHTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTTMTKQRSSRTNNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Z6-1", "uniprot_id": "MYO7A_DROME", "id": "Q9V3Z6-1", "name": "Myosin-VIIa", "aln": "MVIVTRGDYIWIEPASGREFDVAIGARVVSAEGRRIQVRDDDGDEVWLAPE--RRIKAMHASSVQGVEDMISLGDLHEAGILRNLLIRYKENLIYTYTGSILVAVNPYQILPIYTGDQIKLYKERKIGELPPHIFAIGDNAYAHMKRYRQDQCIVISGESGAGKTESTKLILQYLAAISGKHSWIEQQILEANPILEAFGNAKTIRNDNSSRFGKYIDIHFSANGVIEGAKIEQYLLEKSRIVSQNHSERNYHVFYCILAGLSADEKSRLDLGMAADYKYLTGGNSITCEGRDDAAEFSDIRSAMKVLLFSDQEIWEIIKLLAALLHCGNIKYKATVVDNLDATEIPEHINVERVAGLLGLPIQPLIDALTRRTLFAHGETVVSTLSRDQSVDVRDAFVKGIYGRMFVHIVRKINTAIFKPRG----TSRNAIGVLDIFGFENFDQNSFEQFCINYANENLQQFFVQHIFKLEQEEYNHEAINWQHIEFVDNQDALDLIAIKQLNIMALIDEEARFPKGTDQTMLAKLHKTHGSHKNYLKPKSDINTSFGLNHFAGVVFYDTRGFLDKNRDTFSPDLLHLVSQSTNKFLRQIFAQDIEM--------------GAETRKRTPTLSTQFRKSLDALMKTLSSCQPFFIRCIKPNELKKPMMFDRGLCCRQLRYSGMMETIRIRRAGYPIRHGFREFVERYRFLIPGVPPAHR-TDCQAATSRICAVVLGK-SDYQLGHTKVFLKDAHDLFLEQERDRVLTRKILILQRSIRGWVYRRRFLRLRAAAITVQRFWKGYAQRKRYRNMRVGYMRLQALIRSRVLSHRFRHLRGHIVGLQAHARGYLVRREYGHKMWAVIKIQSHVRRMIAMRRYRKLRLEHKQFAEVLQLRKLEEQELLHRG-NKHAREIAEQHYRDRLHELERREIQEQLENRRRVEVNMNIINDAARKQEEPVDDGKLVEAMFDFLPDSSSDAPTPHGGRETSVFNDLPHAQ-NVNQDDIIAPIHIS-EDEEDLSEFKFQKFAATYFQGNVNHQYAKKALKHPLLPLHTQGDQLAAQALWITILRFTGDMPEPKYHT--MDRMDTTSVMSKVTATLGRNFIRSKEFQEAQLMGLD------------PDAFLKQKPRSIRHKLVSLTLKRKNKLGEDVRRRLQDDEYTADSYQSWLQSRPTSNLEKLHFIIGHGILRAELRDEIYCQICKQLTNNPLKSSHARGWILLSLCVGCFAPSEKFVNYLRAFIREGPPGYAPYCEERLKRTFNNGTRNQPPSWLELQATKSKKPIMLPITFMDGNTKTLLADSATTARELCNQLSDKISLKDQFGFSLYIALFDKVSSLGSGGDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEIFAPWHEPTHDQVATNLIYQQVVRGVKFGEYRCDKEEDLAMIAAQQYFIEYSTDMSMERLFTLLPNFIPDFCLSGVDKAIERWAALVLQAYKKSYYVKDKIAPLKIKEDIVSYAKYKWPLLFSRFYEAYRNSGPNLPKNDVIIAVNWTGVYVVDDQEQVLLELSFPEITAVSSQK--------------------------------------TNKVFTQTFSLSTVRGEEFTFQSPNAEDIRDLVVYFLDGLKKRSKYVIALQDYRAPS-DGTSFLSFFKGDLIILEDESCGESVLNNGWCIGRCDRSQERGDFPAETVYVLPTLSKPPQDILALFNIEEAHHGRRLSMAS-NGGAVEPRDRPHTLMEYALDHFRLPPKRTMSKTLTLSSKRSEELWRYSRDPIKAPLLRKLQSKEEFAEEACFAFAAILKYMGDLPSKRPRMGNEITDHIFDGPLKHEILRDEIYCQLMKQLTDNRNRMSEERGWELMWLATGLFACSQGLLKELLLFLRTR-RHPISQDSMHRLQKTIRHGQRKYPPHQVEVEAIQHKTTQIFHKVYFPDDTDEAFEVDSSTRAKDFCNNISQRLSLRTSEGFSLFVKIADKVISVPEGDFFFDFVRHLTDWIKKARPIRDGANPQFTYQVFFMKKLWTNTVPGKDRNADLIFHYHQELPKLLRGYHKCSREEAAKLAALVFRVRFGENKQELQAIPQMLRELIPSDIMKIQSTSEWKRSIVASYNQDGGMTSEDAKVAFLKIVYRWPTFGSAFFEVKQTTEPNYPEMLLIAINKHGVSLIHPVTKDILVTHPFTRISNWSSGNTYFHMTIGNLVRGSKLLCETSLGYKMDDLLTSYISLMLTNMNKNRTIRAN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: :**::*:: .:****.:** * .:. ::** **:..* :: : .**.**.:*::****** ****:************.:.:****************:*.**: ::*: *.::****:*****.*.**.* *:* :*** :******************:******:*******:***.***********************:****. .*.***************: * .*****:***:* *:. ::*.:*.** *:**.**: **. .**** * *::.* ****:*:*:: * *** *****:** **::::* . ***: : .: .*. * : :: .** ***:::**:* :.** :*.:*************:** ** ***::*::. . *.:**:********* *****:***:***:******:*:********: * *:* .***.***:***:** : :*:::*****::****** *** **:. * : **: ** . :*.**::****:*.*:::***:****:: *:::** .* ***::*** *: * * *****:****:**::**: **:**. *****:*******:****:*** ** ***************:******: * ***:***.*:*** **:: * :.: .*: ** .*:*:*:**:**** **::** ***:.:* :::::*: :** * .**::: *. :** *:*: **.* :*:*::***** *** * :.:: * :: :** .*. ***: : ::: **:.:*::.* *** * ::** * *. : * **:.* :. ::*: * :::::** :* *.: :.:* ::. .. : ::::: : :.**::...:*: **.** :.. . *. .. *:** .. : :: : .: :. ::******:** *********...* *.::.**:*** . :****** *:***:*** **:****** * :. .**:*: ***:. : :*:* * .. ** *::**** ****:*.** *:* :** *.: :. :* *:.**************:****. *********.***::*. ***:******:**************:*** **. *************:*** * **.********************:*****.*****:******.**** *:***.***:******************* ******:**************************:*:***.*:.* *********:***********::*:*** :*:***:::*..:: ***:.*: .:*** :: * :*:** : : : *. *.: : . ::*:::*.:*::************:: *** ***.***:********.**:******:****** ****.: * :*:*:*::*:*:** * ********** **:**:.***:*:*: * *: : :.** * *****:* *. **.*:..**. * :*:::*****:: ***:**:: * :*::*. : :: : : . . : :*:** *:: *:** *.* *:*:.: ..: .:.:* :*:*:* .**:*: . **::::** :* *:****** **** * **:**:**: .:* * *:** * *::****:*: : ***:****:**.****. *: ** .: **::: : *:: *.::****::*:*.****** *****************************:***:*****.**: *: *::**********:***:****.******************.::** *.:************.*.**** ** ****.***** *******: **. :*.**::**:* *:*. : :.:: :**:*.*::: *..:****:*: :*:..* : *:**: **:::::*************:::*::**:******* *::**.* ***** *****:*******:****:****************************** *** *.*:* *:. ", "identical_positions": 1230, "similar_positions": 581, "identity": "54.69%" }, { "cls_id": "homologset.agr.FB:FBgn0000318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BRA2-1", "uniprot_id": "TXD17_HUMAN", "id": "Q9BRA2-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MARYEEVSVSGFEEFHRAVEQHNG--KTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRK--NLKVTAVPTLLKYGTPQKLVESECLQANLVEMLFSED-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQM5-1", "uniprot_id": "TXD17_MOUSE", "id": "Q9CQM5-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MATFEEVSVLGFEEFDKAVKEHEG--KTIFAYFSGSKDTEGKSWCPDCVEAEPVIREGLKHVTEDCVFIYCQVGDKPYWKDPNNDFRQ--KLKITAVPTLLKYGTPQKLVESECCQSSLVEMIFSED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DBT3-1", "uniprot_id": "TXD17_DANRE", "id": "Q6DBT3-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MSKYEEVAVHGYEEFCKAVSDRKG--KEIFAYFSGDKDEHGKSWCPDCVKAEPVVRAELPHLPEGTVFIYCQVGDRPYWKDSNNDFKK--TLKLTGVPTLLRYGTPQKLVEEECFKADLVRMMFTED-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMQ9-1", "uniprot_id": "Q9VMQ9_DROME", "id": "Q9VMQ9-1", "name": "Thioredoxin domain-containing protein 17", "aln": "--MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGESWCPYCVKAEPVIHDALKKAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKRPQRLDGERCSNQDLVEMMFEDED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *::** : :.: :. : :.. *:*.** *:**** **:****:: * : . . *:: :**::.**** * *:: . :: :****:: **:* ..* : .**.*:* :: ", "identical_positions": 41, "similar_positions": 44, "identity": "32.03%" }, { "cls_id": "homologset.agr.FB:FBgn0000319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FD5-1", "uniprot_id": "CLH1_MOUSE", "id": "Q68FD5-1", "name": "Clathrin heavy chain 1", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---ESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEE--PLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLT-------KVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGY-TAPPYG----QPQPGFGYSM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11442-1", "uniprot_id": "CLH1_RAT", "id": "P11442-1", "name": "Clathrin heavy chain 1", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---ESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEE--PLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQIWVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNSLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFKPLLLNDLLMVLSPRLAHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLT-------KVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGY-TAPPYG----QPQPGFGYSM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00610-1", "uniprot_id": "CLH1_HUMAN", "id": "Q00610-1", "name": "Clathrin heavy chain 1", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---ESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEE--PLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLT-------KVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGY-TAPPYG----QPQPGFGYSM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R966-1", "uniprot_id": "F1R966_DANRE", "id": "F1R966-1", "name": "Clathrin heavy chain", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICVREKVGEQAQVVIIDMADPNTPIRRPISADSAIMNPASKVIALKAA-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---DSQPVKVFDRHSSLAGCQIINYRTDAKQKWLLLIGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAGFGQFKMEGN-TEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQQFPKKAVDVFFPPEAQNDFPVAMQISSKHDVVYLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHDATAGIIGVNRKGQVLSVCVEEENIIQYITNVLQNPDLALRMAVRNNLAGAEELFGRKFNNLFAGGNFAEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKFESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQFPKIVLYAKKVGYTPDWIFLLRNVMRISPDQGLQFAQMLVQDEE--PLADITQIVDVFMEYNLVQQCTSFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTNYDRAHIAQLCEKAGLLQRALEHYTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLTELFESFKSFEGLFYFLGSIVNFSQDPEVHFKYIQAACKTGQIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLESRIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGTCDQELINVCNENSLFKSLSRYLVRRRDPELWASVLLETNPFRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISSELFEEAFAIFKKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGLVKESIDSYIKADDPSAYMEVVQAADQSGNWEDLVKFLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYEAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEFDNAIITMMSHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFRPLLLNDLLIVLSPRLDHSRAVNFFSKVKQLPLVKPYLRSVQNHNNKSVNEALNNLFISEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDKLYKDAMQYASESKDTELAEELLQWFLDENKKECFAACLFTCYDLLRPDVVLETSWRNNIMDFAMPYFIQVMREYLS-------KVDKLETSESLRKEEEQATETQPIVYGTPQLMLTAGPSVPVPPQQGYGYGYTAAPGYPPQAPQAQPGFGYGM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B3R2-1", "uniprot_id": "A0A8M2B3R2_DANRE", "id": "A0A8M2B3R2-1", "name": "Clathrin heavy chain", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMSDPNTPIRRPISADSAIMNPASKVIALKAA-KTLQIFNIEMKSKMKAHTMTEDVSFWKWISLNTIALVTDNAVYHWSMEG---DSQPIKVFDRHSSLAGCQIINYRTDAKQKWLLLIGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAGFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQAFPKKAVDVFFPPEAQNDFPVAMQISSKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATSGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNNLFAGGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKFESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRNVMRISPEQGLQFSQMLVQDEE--PLADITQIVDVFMEYNLIQQCTSFLLDALKNNRPTEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHVAQLCEKAGLLQRALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSMECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLTELFESFKSFEGLFYFLGSIVNFSQDPEVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDQELIHVCNENSLFKSLSRYLVRRKDPELWASVLLEVNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGLVKEAIDSYIKADDPSAYMEVGQAAAQSGNWEDLVKFLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYEAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWGELVFLYDKYEEYDNAIITMMNHPADAWKESQFKDIITKVANVELYYRAVQFYLEFKPLLLNDLLIVLSPRLDHTRAVNFFSKVKQLPLVKPYLRSVQNHNNKSVNEALNNLFITEEDFQALRTSIDAYDNFDNISLAQSLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDKLYKDAMQYASESKDTELAEELLQWFLEDDKKECFAACLFTCYDLLRPDVVLETAWRHNLMDFSMPYFIQVMREYLSKVDAIKEKVDKLDASESLRKEEEQLTEAQPIVYGTPQLMLTAGPNVAVPPQQPYGYGYPTATGYT---QPAQPGFGYGM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53675-1", "uniprot_id": "CLH2_HUMAN", "id": "P53675-1", "name": "Clathrin heavy chain 2", "aln": "MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAESAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVALVTETAVYHWSMEG---DSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGN-AKPATLFCFAVRNPTG--GKLHIIEVGQPAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASP-LLQYFGILLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEE--PLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLS-------KVDKLDALESLRKQEEHVTEPAPLVFDFDGHE-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29742-1", "uniprot_id": "CLH_DROME", "id": "P29742-1", "name": "Clathrin heavy chain", "aln": "MTQPLPIRFQEHLQLTNVGINANSFSFSTLTMESDKFICVREKVNDTAQVVIIDMNDATNPTRRPISADSAIMNPASKVIALKAQ-KTLQIFNIEMKSKMKAHTMNEDVVFWKWISLNTLALVTETSVFHWSMEG---DSMPQKMFDRHSSLNGCQIINYRCNASQQWLLLVGISALPSRVAGAMQLYSVERKVSQAIEGHAASFATFKIDAN-KEPTTLFCFAVRTATG--GKLHIIEVGAPPNGNQPFAKKAVDVFFPPEAQNDFPVAMQVSAKYDTIYLITKYGYIHLYDMETATCIYMNRISADTIFVTAPHEASGGIIGVNRKGQVLSVTVDEEQIIPYINTVLQNPDLALRMAVRNNLAGAEDLFVRKFNKLFTAGQYAEAAKVAALAPKAILRTPQTIQRFQQVQTPAGSTTPPLLQYFGILLDQGKLNKFESLELCRPVLLQGKKQLCEKWLKEEKLECSEELGDLVKASDLTLALSIYLRANVPNKVIQCFAETGQFQKIVLYAKKVNYTPDYVFLLRSVMRSNPEQGAGFASMLVAEEE--PLADINQIVDIFMEHSMVQQCTAFLLDALKHNRPAEGALQTRLLEMNLMSAPQVADAILGNAMFTHYDRAHIAQLCEKAGLLQRALEHYTDLYDIKRAVVHTHMLNAEWLVSFFGTLSVEDSLECLKAMLTANLRQNLQICVQIATKYHEQLTNKALIDLFEGFKSYDGLFYFLSSIVNFSQDPEVHFKYIQAACKTNQIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVVGGLLDVDCSEDIIKNLILVVKGQFSTDELVEEVEKRNRLKLLLPWLESRVHEGCVEPATHNALAKIYIDSNNNPERYLKENQYYDSRVVGRYCEKRDPHLACVAYERGLCDRELIAVCNENSLFKSEARYLVGRRDAELWAEVLSESNPYKRQLIDQVVQTALSETQDPDDISVTVKAFMTADLPNELIELLEKIILDSSVFSDHRNLQNLLILTAIKADRTRVMDYINRLENYDAPDIANIAISNQLYEEAFAIFKKFDVNTSAIQVLIDQVNNLERANEFAERCNEPAVWSQLAKAQLQQGLVKEAIDSYIKADDPSAYVDVVDVASKVESWDDLVRYLQMARKKARESYIESELIYAYARTGRLADLEEFISGPNHADIQKIGNRCFSDGMYDAAKLLYNNVSNFARLAITLVYLKEFQGAVDSARKANSTRTWKEVCFACVDAEEFRLAQMCGLHIVVHADELEDLINYYQNRGYFDELIALLESALGLERAHMGMFTELAILYSKFKPSKMREHLELFWSRVNIPKVLRAAESAHLWSELVFLYDKYEEYDNAVLAMMAHPTEAWREGHFKDIITKVANIELYYKAIEFYLDFKPLLLNDMLLVLAPRMDHTRAVSYFSKTGYLPLVKPYLRSVQSLNNKAINEALNGLLIDEEDYQGLRNSIDGFDNFDNIALAQKLEKHELTEFRRIAAYLYKGNNRWKQSVELCKKDKLYKDAMEYAAESCKQDIAEELLGWFLERDAYDCFAACLYQCYDLLRPDVILELAWKHKIVDFAMPYLIQVLREYTT-------KVDKLELNEAQREKEDDSTEHKNIIQMEPQLMITAGPAMGIPPQYAQNYPPGAATVTA----AGGRNMGYPYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22137-1", "uniprot_id": "CLH_YEAST", "id": "P22137-1", "name": "Clathrin heavy chain", "aln": "-MSDLPIEFTELVDLMSLGISPQFLDFRSTTFESDHFVTVRETKDGTNSVAIVDLAKGNEVTRKNMGGDSAIMHPSQMVISVRANGTIVQIFNLETKSKLKSFTLDEPVIFWRWLSETTLGFVTARSILTSNVFDGNVNAKPQLLTLRHANLNNTQIINFVANKNLDWFAVVGILQENGRIAGRIQLFSKQRNISQAIDGHVAIFTNILLEGNGSTPVQVFVTGNRNATTGAGELRIIEIDHDASLPSQYQKETTDIFFPPDATNDFPIAVQVSEKYGIIYLLTKYGFIHLYELETGTNLFVNRITAESVFTAAPYNHENGIACINKKGQVLAVEISTSQIVPYILNKLSNVALALIVATRGGLPGADDLFQKQFESLLLQNDYQNAAKVAASSTS--LRNQNTINRLKNIQAPPGAISP-ILLYFSTLLDKGKLNKEETIELARPVLQQDRKQLFEKWLKEDKLECSEELGDIVKPFDTTLALACYLRAGAHAKVISCLAELQQFEKIIPYCQKVGYQPNFLVLISSLIRSSPDRASEFAVSLLQNPETASQIDIEKIADLFFSQNHIQQGTSLLLDALKGDTPDQGHLQTRVLEVNLLHAPQVADAILGNNIFSHYDKPTIASLSEKAGLYQRALENYTDIKDIKRCVVHTNALPIDWLVGYFGKLNVEQSLACLKALMDNNIQANIQTVVQVATKFSDLIGPSTLIKLFEDYNATEGLYYYLASLVNLTEDKDVVYKYIEAAAKMKQYREIERIVKDNNVYDPERVKNFLKDANLEDQLPLVIVCDRFDFVHEMILYLYKSQNLKFIETYVQQVNPSKTAQVVGALLDMDCDEAFIQSLLQSVLGQVPINELTTEVEKRNRLKILLPFLEQSLSQGIQDQAVYNALAKIYIDSNNSPEKFLKENDQYDTLDVGHYCEKRDPYLAYIAYEKGQNDDDLIRITNENSMYKYQARYLLERSDLDLWNKVLNQENIHRRQLIDSVISVGIPELTDPEPVSLTVQAFMTNGLKLELIELLEKIILEPSPFNENVALQGLLLLSAIKYEPTKVSSYIEKLDNYDADEIAPLCIEHDLKEEAFEIYDKHEMYGKALKVLIEDIMSLDRAASYADKINTPELWSQIGTAQLDGLRIPDAIESYIKAEDPSNYENVIDIAEQAGKYEELIPFLLMARKTLKEPKIDGALILAYAELNKIHEIENLLAGSNVANLDHVGDKLFENKEYKAARLCYSAVSNYSKLASTLVYLGDYQAAVDTARKASNIKVWKLVNDACIEKKEFKLAQICGLNLIVHAEELDELVERYESNGYFEELISLFEAGLGLERAHMGMFTELAILYSKYEPDKTFEHLKLFWSRINIPKVIRAVEQAHLWSELVFLYAHYDEWDNAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINFYVKFHPSLLVDLLTSLTPRLDIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQAYHDLMIEEEDYKALQDAVDSYDKFDQLGLASRLESHKLIFFKKIGALLYRRNKKWAKSLSILKEEKLWKDAIETAAISQDPKVVEALLTYFVETGNREGFVALLYAAYNLVRIEFVLEISWMNSLEDYIKPFEISIKKEQND---------SIKKITEELAKKSGSNEEHK---DGQPLMLMNS--AMNVQPTGF---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:.* * .:* .:**.. :.* : *:***:*: :**. . .*.*:*: . *: :..:****:*:. **:::* . :****:* ***:*:.*: : * **:*:* .*:.:** :: .: . :: * : **:.* . *:*:: : .*: : ** .*:.* :**:* :*::**.*:**.* * : ::.* :* . * : *:*:***:. . . : *::.*:****:* ****:*:*:. *:. ::*:****::***::*:.. : :***:.:::*.:**:. ** :*:*****:* :. .:*: * . *.* *.* :*.*..*.**:.** ::*: *: ..: :****** :.. **. :*:.:::.: : .* :* :* **. ***:*:*** *::**.: ** *.:*** ******:**********:**. * ***: ****.. ***.*:** *. **: *.:**.* *:::.*: .::: .*::. *: *: : * . :* :*.*:*:. . :** *::****** : * :* *** :**:**: *********** :*::**:. :*.*.***** *:***::**: ****.****: * :***.:**.*.**:*: **:*:: *:: *:* **:*:*: : : .:* .***.::: .**:*:*.*:**:::* :* ***:**.* * :*:*** ::.. *:*********:*:* *****:******.***:::****:.. ::** ***:****: . *:*.***:**.* .*: *: * **.. :**. *********:***:** : :* : *.:************.** :*:** **: **:*******:** :***:* * :** : ****::* :***: * * :** ** : * :* ***.*:...:.* **: :*:**:**** .* *********:*: * *.:: **.**:*:*** : *:* .**.:*:**** :** :.:. * **** :: *.:: .*::***:.: .*:** .:*:: * * :***:. ***: : ::*:***:.:*** * :* : * .:::*: :* ****. :*. :: ** * *. .:: ::*::: *.* *.::::*:: :.: *.**:* *. ***:.:** ***:* ::*.*** :***.. :.** * **:: :**::**:***::::**:**::*: *:..***:*** ::*:.********************::*.* ***:*****:*****:**.*.****.****** :*:*:*** :::: :.:. .. **:::.**:*:*: *:*::**:.::* *: *:* *:**: . :*. *** ***:**:* .* **. :*:: : *: ***::.*: ::*.:*:**::.**. **.*:* *: *.* *:: *: * :*:.: *:: *:***:: *: * . .:.: ** :*:: : * * *: .*:*:* :.:** :* :.: * *: *.: :* . . * ::. * ", "identical_positions": 698, "similar_positions": 566, "identity": "41.11%" }, { "cls_id": "homologset.agr.FB:FBgn0000320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AMN9-1", "uniprot_id": "A0A8I6AMN9_RAT", "id": "A0A8I6AMN9-1", "name": "Eyes absent homolog", "aln": "-------------------------------------------MEEEQDLPE---------RPVKKAKMQEPGEQTLSQVNNPDT-------------------------------------------------SDQKPETASLASNLSMSEEIMTCTDYIPRSSNDYTS-QMYSA------------------KPYAHILSVPVS--ETTYPGQTQYQT-LQQSQPYAVYPQATQTYGLPPFG----ALWPGMKPESGLIQT--------PSPSQHSVLTCTTGLTTSQPSPAHYS-YPIPASSTNASLISTSSAIANIPAAAVASISNQDYPTYTILGQN--------QYQACYPSSSFGVTGQTNS------------------------DTENTALAATTYQTEKPGAMGPAPATQRLPS-DSSTSPPLSQTTPNKDADDQAR-KNMTV-----------KNRGKRKADASSSQDSE-----------LERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSG---SGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97480-1", "uniprot_id": "EYA3_MOUSE", "id": "P97480-1", "name": "Protein phosphatase EYA3", "aln": "--------------------------------------------------------------------MQEPREQTLSQVNNPDA-------------------------------------------------SDEKPETSSLASNLSMSEEIMTCTDYIPRSSNDYTS-QMYSA------------------KPYAHILSVPVS--ETTYPGQTQYQT-LQQSQPYAVYPQATQTYGLPPF-----------------------------------------------------------ASSTNASLIPTSSAIANIPAAAVASISNQDYPTYTILGQN--------QYQACYPSSSFGVTGQTNS------------------------DAETTTLAATTYQTEKPSAMVPAPATQRLPS-DSSASPPLSQTTPNKDADDQAR-KNMTV-----------KNRGKRKADASSSQDSE-----------LERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSG---SGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCANVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99504-1", "uniprot_id": "EYA3_HUMAN", "id": "Q99504-1", "name": "Protein phosphatase EYA3", "aln": "-------------------------------------------MEEEQDLPE---------QPVKKAKMQESGEQTISQVSNPDV-------------------------------------------------SDQKPETSSLASNLPMSEEIMTCTDYIPRSSNDYTS-QMYSA------------------KPYAHILSVPVS--ETAYPGQTQYQT-LQQTQPYAVYPQATQTYGLPPFG----ALWPGMKPESGLIQT--------PSPSQHSVLTCTTGLTTSQPSPAHYS-YPIQASSTNASLISTSSTIANIPAAAVASISNQDYPTYTILGQN--------QYQACYPSSSFGVTGQTNS------------------------DAESTTLAATTYQSEKPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSR-KNMTS-----------KNRGKRKADATSSQDSE-----------LERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSG---SGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVI5-1", "uniprot_id": "D3ZVI5_RAT", "id": "D3ZVI5-1", "name": "Eyes absent homolog", "aln": "--------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLDSSHINSTSMTPNGTE------------------------------------------VKTEPMSSSEIASTAADGSLDSFSGSALGSSSFSPRPAHPFSPPQIYPS------------------KPYPHILPTPSSQTMAAYG-QTQFTTGMQQATAYATYPQPGQHYGISSYG----ALWAGIKTEGGLSQS--------QSPGQTGFLSYGTSFGTPQPGQAPYS-YQMQ-GSSFTTSSGLYTGNNSLTNSSGFNSSQQDYPSYPGFGQG--------QYAQYYNSSPYPAHYMTSSN-----------------------TSPTTPSTNATYQLQEPPSGVTSQAVTD-PTAEYSTIHSPSTPIKESDSDRLRRGSDGKS-----------RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPA---AATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRANCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97767-1", "uniprot_id": "EYA1_MOUSE", "id": "P97767-1", "name": "Protein phosphatase EYA1", "aln": "--------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLDSSHINSTSMTPNGTE------------------------------------------VKTEPMSSSEIASTAADGSLDSFSGSALGSSSFSPRPAHPFSPPQIYPS------------------KSYPHILPTPSSQTMAAYG-QTQFTTGMQQATAYATYPQPGQPYGISSYG----ALWAGIKTESGLSQS--------QSPGQTGFLSYGTSFGTPQPGQAPYS-YQMQ-GSSFTTSSGLYSGNNSLTNSSGFNSSQQDYPSYPGFGQG--------QYAQYYNSSPYPAHYMTSSN-----------------------TSPTTPSTNATYQLQEPPSGVTSQAVTD-PTAEYSTIHSPSTPIKETDSERLRRGSDGKS-----------RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPA---AATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99502-1", "uniprot_id": "EYA1_HUMAN", "id": "Q99502-1", "name": "Protein phosphatase EYA1", "aln": "--------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTE------------------------------------------VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSN-----------------RPYPHILPTPSSQTMAAYG-QTQFTTGMQQATAYATYPQPGQPYGISSYG----ALWAGIKTEGGLSQS--------QSPGQTGFLSYGTSFSTPQPGQAPYS-YQMQ-GSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQG--------QYAQYYNSSPYPAHYMTSSN-----------------------TSPTTPSTNATYQLQEPPSGITSQAVTD-PTAEYSTIHSPSTPIKDSDSDRLRRGSDGKS-----------RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPA---AATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9H5-1", "uniprot_id": "A0A8M2B9H5_DANRE", "id": "A0A8M2B9H5-1", "name": "Eyes absent homolog", "aln": "--------------------------------------------MEMQDLASPHSRVSGSSESPNGPNIDNSHINNNSMTPNGTE------------------------------------------VKTEPMSSSEIATSVADGSLDSFSGSAIGTSGFSPRQTHQFSP-QIYPS------------------KPYPHILPTPSAQNMAAYG-QTQYTTGMQQAAAYGTYPQPGQPYGISAY---------GIKTEGGLTQA--------QSPGQSGFLSYSSSFSTPQTGQAPYS-YQMQ-GGSFTTTSGLYAGSNSLTNSTGFNSTQQDYPSYPTFGQS--------QYAQYYNSSPYTSPYMTSNN-----------------------TSPTTPSTTATYTLQEPPSGITSQALTEQPTGEYSTIHSPSTPIKDSDSDRLRRASDVKA-----------RGRGRRNNNPSPPPDSD-----------LERVFIWDLDETIIVFHSLLTGSYANRFGRDPPTSVSLGLRMEEMIFNLADTHFFFNDLEECDQVHIDDVSSDDNGQDLSTYNFSTDGFHA---AATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRSNCVNILVTTTQLIPALAKVLLYGLGVVFPIENIYSATKIGKESCFERVIQRFGRKVVYVVVGDGVEEEQGSKKHNMPFWRISSHSDLMALHHALDLEYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AS60-1", "uniprot_id": "A0A8I6AS60_RAT", "id": "A0A8I6AS60-1", "name": "Eyes absent homolog", "aln": "---------------MEDTQDLNEQSVKKTCPESDVSEPQNSRSMEMQDLASPHALVGG-SDTPGSSKLDKSGLSSTSVTTNGTGGDNM--------------TVLNTADWLLSCNTPSSATMSLLAVKTEPLHSSETTTTTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS------------------KPYPHILSTPAAQTMSAYAGQTQYSG-MQQPAVYTAYSQTGQPYSLPAY--DLGVMLPAIKTESGLPQT--------QSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP-GSSFAPSSTIY-ANNSVSNSTNFSGSQQDYPSYTAFGQN--------QYAQYYSASTY-GAYMTSNN-----------------------TADGTSSSTSTYQLQESLQG---LTSQP---GEFDTVQSPSTPIKDLD-DRTCRSSGSKS-----------RGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHA---TASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z191-1", "uniprot_id": "EYA4_MOUSE", "id": "Q9Z191-1", "name": "Protein phosphatase EYA4", "aln": "---------------MEDTQDLNEQSVKKTCPEADVSEPQNSRSMEMQDLASPHALVGG-SDTPGSSKLDKSGLSSTSVTTNGTG-------------------------------------VSLLAVKTEPLHSSESTTTTGDGALDTFTGSVITSSGYSPRSAQQYSP-QLYPS------------------KPYPHILSTPAAQTMSAYAGQTQYSG-MQQPAVYTAYSQTGQPYSLPAY--DLGVMLPAIKTESGLSQT--------QSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP-GSSFAPSSTIY-ANNSVSNSTNFSSSQQDYPSYTAFGQN--------QYAQYYSASTY-GAYMTSNN-----------------------TADGTSSSTSTYQLQESLQG---LTSQP---GEFDTVQSPSTPIKDLD-DRTCRSSGSKS-----------RGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHA---AASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95677-1", "uniprot_id": "EYA4_HUMAN", "id": "O95677-1", "name": "Protein phosphatase EYA4", "aln": "---------------MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGG-GDTPGSSKLEKSNLSSTSVTTNGTGGENM--------------TVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS------------------KPYPHILSTPAAQTMSAYAGQTQYSG-MQQPAVYTAYSQTGQPYSLPTY--DLGVMLPAIKTESGLSQT--------QSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP-GSSFAPSSTIY-ANNSVSNSTNFSGSQQDYPSYTAFGQN--------QYAQYYSASTY-GAYMTSNN-----------------------TADGTPSSTSTYQLQESLPG---LTNQP---GEFDTMQSPSTPIKDLD-ERTCRSSGSKS-----------RGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHA---AASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IJR1-1", "uniprot_id": "A0AC58IJR1_DANRE", "id": "A0AC58IJR1-1", "name": "Eyes absent homolog", "aln": "---------------MENTQDLNEQSVKKSTTDSHAPDPVDNRALEMQELTDVQHSVN--SGSDGTSKLDKNILSNN-ITTNGTGGENM--------------TILNTADWLLGCSSPPTAPSMKNDVKSEPLNSSEAVSSAGDSGLDTYTGSVISSSGFSPRPAHQYSP-PLYPS------------------KPYPHILTTPVAPPMSAYTGQSQFSS-MQQSTVYTPYSQTTPPYGLSTYATDLGVMLPGIKTEGGLTQT--------QSTLQSG-LSYSPGFTTPQPGQTAYSPYQMPAGSGFTTSPGLY-TSN-NSNPGNFTTQQQEYPSYTTFGQN--------QYAQYYSTSSY-GSYMTSNS-----------------------SLDGTG-SVSTYQLQDPIMTGQAADLNP---GEFEAGQSPSTPIKEME-DRACRGGGAKA-----------RGRGRKNN-PSPPPDSD-----------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHA---AATSASLCLATGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K1T5-1", "uniprot_id": "A0A0G2K1T5_RAT", "id": "A0A0G2K1T5-1", "name": "Eyes absent homolog", "aln": "---------------------------------------------------------------------MLEVVISPSLAASSD--------------------------------------------------WGEHGAAVG--ALTDREGTAKAASLSVP---------QLFAK-------------------SHPRVPPGQSSAAMAAYG-QTQYSTGIQQTPPYTAYPPPAQAYGIPPYS---------IKTEDSLN----------HSPSQSGFLSYGPSFSTAPAGQSPYT-YPVH------STAGLYQGANGLTNTAGFGSVHQDYPSYPNFPQN--------QYPQYFS-PSYNPPYVPAS------------------------SLCSSPLSTSTYVLQEAPHNVS-QSSES-LAGDYNTHNGPSTPAKEGDTDRPHRASDGKL-----------RGRSKRSSDPSPAGDNE-----------IERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSTDGFHS---TAPGASLCLGTGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGGLIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08575-1", "uniprot_id": "EYA2_MOUSE", "id": "O08575-1", "name": "Protein phosphatase EYA2", "aln": "---------------------------------------------------------------------MLEVVTSPSLATSSD--------------------------------------------------WSEHGAAVG--TLSDREGIAKSAALSVP---------QLFVK-------------------SHPRVPPGQSSTAMAAYG-QTQYSTGIQQAPPYTAYPTPAQAYGIPPYS---------IKTEDSLN----------HSPSQSGFLSYGPSFSTAPAGQSPYT-YPVH------STAGLYQGANGLTNTAGFGSVHQDYPSYPSFSQN--------QYPQYFS-PSYNPPYVPAS------------------------SLCSSPLSTSTYVLQEAPHNVPSQSSES-LAGDYNTHNGPSTPAKEGDTERPHRASDGKL-----------RGRSKRNSDPSPAGDNE-----------IERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSTDGFHS---TAPGASLCLGTGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGGLIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00167-1", "uniprot_id": "EYA2_HUMAN", "id": "O00167-1", "name": "Protein phosphatase EYA2", "aln": "---------------------------------------------------------------------MVELVISPSLTVNSDC--------------------------------------------LDKLKFNRADAAVW--TLSDRQGITKSAPLRVS---------QLFSR-------------------SCPRVLPRQPSTAMAAYG-QTQYSAGIQQATPYTAYPPPAQAYGIPSYS---------IKTEDSLN----------HSPGQSGFLSYGSSFSTSPTGQSPYT-YQMH------GTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQS--------QYPQYYG-SSYNPPYVPAS------------------------SICPSPLSTSTYVLQEASHNVPNQSSES-LAGEYNTHNGPSTPAKEGDTDRPHRASDGKL-----------RGRSKRSSDPSPAGDNE-----------IERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHS---SAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05201-1", "uniprot_id": "EYA_DROME", "id": "Q05201-1", "name": "Protein phosphatase eya", "aln": "MVTLMPYNYAAPRCGLIDKMIEPKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLASNGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFAQSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNPLDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPGAAAAAAAYLTPSYAASGNN-NSQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDTHSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQPSPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. . .: . : : * ::: . . . *. * : * ** : . : . : :*: ... : .: : . . . : *.:: .:.. .. ****:******:*:**:**:*::*.:: :* . : .: ****:*::****:***::*:***:*::*.:********. *.*.:*** .. . **:**************:::::* .::.*** *:.. :::: ::*:*:* ** * :**.* :* * ** *:*:*:*** ********:.** * ******* * *:*:*:**:: *** : .*:*:*** :** .:. :****:: *.*: :* **:: :*", "identical_positions": 141, "similar_positions": 131, "identity": "18.38%" }, { "cls_id": "homologset.agr.FB:FBgn0000326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23141-1", "uniprot_id": "EST1_HUMAN", "id": "P23141-1", "name": "Liver carboxylesterase 1", "aln": "---MWLRA---FILATLSASAAWGHPSSP-PVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKP-LAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLD----LQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK------EGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYN---QKEGYLQIGANTQAAQKLKDKEVAFWTN----LFAKKAVEKPPQTEHIEL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCT4-1", "uniprot_id": "EST1D_MOUSE", "id": "Q8VCT4-1", "name": "Carboxylesterase 1D", "aln": "---MGLYP---LIWLSLAACTAWGYPSSP-PVVNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVG-GASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITT-DVKP-IAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLD----LLGNPKESYPFLPTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQEFGWIIPT-LMGYPLAEGKLDQKTANSLLWKSYPTLKISENMIPVVAEKYLGGTDDLTKKKDLFQDLMADVVFGVPSVIVSRSHRDAGASTYMYEFEYRPSFVSAMRPKAVIGDHGDEIFSVFGSPFLK------DGASEEETNLSKMVMKFWANFARNGNPNGGGLPHWPEYD---QKEGYLKIGASTQAAQRLKDKEVSFWAE----LRAKESAQRPSHREHVEL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z5G7-1", "uniprot_id": "D3Z5G7_MOUSE", "id": "D3Z5G7-1", "name": "Carboxylic ester hydrolase", "aln": "---MWLHA---LVWASLALCPIWGHSPSS-PVVDTTQGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTG-GASLYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLVACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVG----GAASAKKDNTSMSTVIDGVVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPT-MLGDLLSEGKMNEETASLLLRRFHSDLNISESLIPAVIEKYLRGTDDPAKKRDLLLDMFSDVFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFSVFGIPLLK------EGTSEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYD---EKEGYLQIGATTQQAQRLKAEEVAFWTE----LLAKNPPETDP-TEHREHK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NT32-1", "uniprot_id": "EST5A_HUMAN", "id": "Q6NT32-1", "name": "Carboxylesterase 5A", "aln": "MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQN--SEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTR-------------------VVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYN---LTEQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2F4-1", "uniprot_id": "Q9W2F4_DROME", "id": "Q9W2F4-1", "name": "carboxylesterase", "aln": "---MLLRPCGRLIFTRFCSSMKVKVPVKQGVLVGRQKKLVNG---------LEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKE------------GNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLD--PQAPEAQEAASDIRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMWANFARDGKPSPIWKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRS----MYRRYRSENFEAVRAKL-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: . . . : * ***:*:* **:* *** *.* . :. . * *****:**:*:* . . ***:**: **.: * . * :. * ::*:**.::**** *::: :: ** . ** ** ***.** *.*:*..**:**.***. ** :: ** ***:** :*.. : * * .:: *: : : . : . * . . : : : ::* ::* *. * :: . . . *: . . :: . : * : *::.* * : . .. . :* :. . :. : . . * ..:: ::. : : **.*** *:*. . :: * :. . .. . .: ** . : ", "identical_positions": 98, "similar_positions": 129, "identity": "16.2%" }, { "cls_id": "homologset.agr.FB:FBgn0000330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53678-1", "uniprot_id": "AP3M2_RAT", "id": "P53678-1", "name": "AP-3 complex subunit mu-2", "aln": "MIHSLFLINSAGDIFLEKHWKSVVS---------RSVCDYFFEAQERATEAEN-VPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG--VCSEPVIKDNVVVVYEVLEEMLDNGFPLATES---NILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLS-------------------VVPWRRT-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVTAEIQGVIDACVKLTGMPDLTLSFMNP-RLLDDVSFHPCVRFKR-WESERILSFIPPDGNFRLLSYHVSAQNLVAIP---VYVKHSISFRDSGSLGR----FEITVGPK-QTMGKTIEGVTVTSQMPKGVLN--------MSLTPSQGTHTFDPVTKMLSWDVGKINPQ-KLPSLKGTMGLQVGAS---KPDENPTINLQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGIKYMTKAGKFQVRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2R9-1", "uniprot_id": "AP3M2_MOUSE", "id": "Q8R2R9-1", "name": "AP-3 complex subunit mu-2", "aln": "MIHSLFLINSSGDIFLEKHWKSVVS---------RSVCDYFFEAQERATEAEN-VPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG--VCSEPVIKDNVVVVYEVLEEMLDNGFPLATES---NILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLS-------------------VVPWRRT-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVTAEIQGVIDACVKLTGMPDLTLSFMNP-RLLDDVSFHPCVRFKR-WESERILSFIPPDGNFRLLAYHVSAQNLVAIP---VYVKHSISFRDSSSLGR----FEITVGPK-QTMGKTIEGVIVTSQMPKGVLN--------MSLTPSQGTHTFDPVTKMLSWDVGKINPQ-KLPSLKGTMGLQVGAS---KPDENPTINLQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGIKYMTKAGKFQVRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53677-1", "uniprot_id": "AP3M2_HUMAN", "id": "P53677-1", "name": "AP-3 complex subunit mu-2", "aln": "MIHSLFLINSSGDIFLEKHWKSVVS---------RSVCDYFFEAQERATEAEN-VPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG--VCSEPVIKDNVVVVYEVLEEMLDNGFPLATES---NILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLS-------------------VVPWRRT-GVKYTNNEAYFDVIEEIDAIIDKSGS---TITAEIQGVIDACVKLTGMPDLTLSFMNP-RLLDDVSFHPCVRFKR-WESERILSFIPPDGNFRLLSYHVSAQNLVAIP---VYVKHNISFRDSSSLGR----FEITVGPK-QTMGKTIEGVTVTSQMPKGVLN--------MSLTPSQGTHTFDPVTKMLSWDVGKINPQ-KLPSLKGTMSLQAGAS---KPDENPTINLQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGIKYMTKAGKFQVRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKC8-1", "uniprot_id": "AP3M1_MOUSE", "id": "Q9JKC8-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVEN-VPPVISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLS-------------------NIPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIP---VYVKHSISFKENSSCGR----FDITIGPK-QNMGKTIEGITVTVHMPKVVLN--------MNLTPTQGSYTFDPVTKVLAWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPNLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYVTKAGKFQVRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53676-1", "uniprot_id": "AP3M1_RAT", "id": "P53676-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVEN-VPTVISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLS-------------------NIPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIP---VYVKHNISFKENSSCGR----FDITIGPK-QNMGKTIEGITVTVHMPKVVLN--------MNLTPTQGSYTFDPVTKVLAWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPNLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYITKAGKFQVRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T2-1", "uniprot_id": "AP3M1_HUMAN", "id": "Q9Y2T2-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVEN-VPPVISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLS-------------------NIPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIP---VYVKHSISFKENSSCGR----FDITIGPK-QNMGKTIEGITVTVHMPKVVLN--------MNLTPTQGSYTFDPVTKVLTWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPSLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYVTKAGKFQVRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76928-1", "uniprot_id": "O76928_DROME", "id": "O76928-1", "name": "", "aln": "MIHSLFIVNSGGEVFLEKHWRSVVS---------RSVCEYFLDAQR--AAPYD-VPPVIATPHYYLITVQRDTVSLVAACKQEVPPLFVIEFLHRVVDTFQDYFG--DCSESVIKDNYVVVYELLDEMLDNGFPLATES---NILKELIKPPNILRTIANTVTGKSNVSTTLPSGQLS-------------------AVRWRRS-GVRYTNNEAYFDVIEEVDAIIDKSGS---TVFAEIQGHIDCCIKLSGMPDLTLSFMNP-RLFDDVSFHPCVRYKR-WEAERLLSFIPPDGNFRLMSYHISSQSVVAIP---IYIRHNFSIK-TGEQGR----LDLTIGPR-NTLGRTVDKVKLELTMPRCVLN--------CLLTPNQGKYTFDSVTKTLSWDVGRIDVS-KLPNIRGSVSITPGTT---NIDANPSVNVQFQISQLAVSGLKVNRLDMYG-----EKYKPFKGVKYLTKAGKFQVRM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38153-1", "uniprot_id": "AP3M_YEAST", "id": "P38153-1", "name": "AP-3 complex subunit mu", "aln": "MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVQSTCPQLLEDSSSDDYLDHSMVGRDLEVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLEYFDKDKLSIKKIVNNYDRISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFISSTAHNLQQAVQLPQQRQQQLQQNQISRGSNSLIENEEIVPWRTSRASKHENNELYVDLLETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGIPSLHDCVEINDGVFSPSNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSIGLMSLHFQNGLGKDSDEFELSLNIENFKKVSQVDDLKIDLQFNVENADPNEIAYKIKILRNTHGRFENSIIMGQGQWIFDKSTATGTVPVLRGCIEYENTGPNFTKKVDLQTVSLEYSYIGQSASGIYVEAIDIVSGLTIGKNTKLYKGAKYKTQTGNFQVRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::: : ..:::: :... :*.* ::: . . : : *: : : . :: . . ** : **. : : :**. * * :* : ::: :: * * .:: * :** : . * .. .: : . : . ** : . : ** : . :: *** *.*::* ...:::*. * : ..*:* :* *.. * :::.: . . :. *:* *:. : : ::******:***: * :. .. * . : :*:: . *: :::::. . . :: : : : : * .:* . . : * ..: .:* ::* : . : .:.:::. : **: *: :*: . :: * :** ** *::*:**** ", "identical_positions": 73, "similar_positions": 159, "identity": "15.11%" }, { "cls_id": "homologset.agr.FB:FBgn0000337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88867-1", "uniprot_id": "KMO_RAT", "id": "O88867-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MASSDTEGKRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRG--RSINLALSYRGRQALKAVG--LEDQIVSKGVPMKARMIHSLSGKKSAIPYG-NKSQYILSISREKLNKDLLTAVESYPNAKVHFGHKLSKCCPEEGI----LTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKKPRFDYSQQYIPHGYMELTIPP-------KNGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTH-SDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKS-RCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTR-IRYHEAVLRWHWQKKVINRGLFVLGSLVAIGSAYILVHHLSPRPLELLR------SAWTGTSGHWNRSADISPRVP--WSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WN4-1", "uniprot_id": "KMO_MOUSE", "id": "Q91WN4-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MASSDTQGKRVAVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVAKSARG--RSINLALSYRGRQALKAIG--LEDQIVSKGVPMKARMIHSLSGKKSAIPYG-NKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCIPEEGV----LTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPP-------KNGEYAMEPNCLHIWPRNAYMMIALPNMDKSFTCTLFMPFEEFERLPTR-SDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKS-HCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNNLSMCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQKLLDKFLHAIMPSTFIPLYTMVAFTR-IRYHEAVLRWHWQKKVINRGLFVLGSLIAIGGTYLLVHHLSLRPLEFLRR-----PAWMGTTGYWTRSTDISLQVP--WSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15229-1", "uniprot_id": "KMO_HUMAN", "id": "O15229-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRG--RSINLALSHRGRQALKAVG--LEDQIVSQGIPMRARMIHSLSGKKSAIPYG-TKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGM----ITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPP-------KNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTS-NDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS-HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSR-IRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLY6-1", "uniprot_id": "KMO_DANRE", "id": "Q1RLY6-1", "name": "Kynurenine 3-monooxygenase", "aln": "------------METAFSHPPQSSSSKRKVIAVVGGGLVGSLNACFLAKRGFDVEVYESREDIRQAKVVKG--RSINLALSHRGRQALKHVG--MEDKIISKGIPMHARMIHNVNGKRSPIPYG-KKGQYILSVDRANLNKELLTAAEAYPNTRLNFNHKLHDWSPKTGT----MTFIGSDGQKTETQADLIVGCDGAFSAVRKQFLRQSRFNYSQTYIPHGYMELTMPP-------KDGDFAMEPNYLHIWPRNTFMMIALPNLDRTFTCTLFMPFEDFEKIRTG-DELLRFFHKYFPDSVPLIGVEALKQDFFRLPAQAMVSVKCCPYHLFE-KCVLMGDAAHAVVPFYGQGMNAGFEDCLVFDEIMDQFNENLVAVLQEYTRVRVPDDHAIADLAMYNYIEMRAHVNSKYFIFRKYLDNLLHFFMPKTIVPLYTMVTFTR-TRYNDAVNRWHWQNKVITRGLWLCGFVSAAGGTYVLVKNSHKLP-------------SISAEQLWTRILALKLF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z746-1", "uniprot_id": "KMO_DROME", "id": "A1Z746-1", "name": "Kynurenine 3-monooxygenase", "aln": "MSPGIVSQEVNGRQEPTEAARDERHGRRRRVAVIGAGLVGSLAALNFARMGNHVDLYEYREDIRQALVVQG--RSINLALSQRGRKALAAVG--LEQEVLATAIPMRGRMLHDVRGNSSVVLYDPINNQCLYSVGRRQLNEVLLNACDKLPNIRCHFEHKLTSANLREGS----MEFRNPAKEAVAAHADLIVGCDGAFSSVRQNNVRLPGFNYSQEYIETGYLELCIPS-------KSGDFQMPANYLHIWPRNTFMMIALPNQDKSFTVTLSMPFEIFAGIQNQ-NDLLEFFKLNFRDALPLIGEQQLIKDFFKTRPQFLVSIKCRPYHYAD-KALILGDAAHAMVPYYGQGMNAGMEDVTLLTDILAKQLP-LDETLALFTESRWQDAFAICDLAMYNYVEMRDLTKRWTFRLRKWLDTLLFRLFPG-WIPLYNSVSFSS-MPYRQCIANRKWQDQLLKR-IFGATFLAAIVTGGAIYAQRFL---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38169-1", "uniprot_id": "KMO_YEAST", "id": "P38169-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------------MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYG-LHGEAINSINRSVLNNSLLDELEKS-TTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGMLSIGGYKLFKFLTRERS-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.::*.****.* * ::: . .: :*: *:* * . :*****:* ** .** :. :.:: :**:.**:*.: *. . *. :.: : *:.* **: ** : . . :* *:* . . : . *:::*****:*:.* : : ::::* *: *:** :*. .*:: : .: ******: :*:***.* : :** *: . : : : . . : *: * * : ::. . : *: : ::.::* .:. :.:::******:**::*****.*:** :: :: : : ::. * * :* :*: ** ** .. * ::: :: :: :: :***. ::* * .: . * :::. : : : ", "identical_positions": 102, "similar_positions": 151, "identity": "19.43%" }, { "cls_id": "homologset.agr.FB:FBgn0000339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PI25-1", "uniprot_id": "CNIH2_HUMAN", "id": "Q6PI25-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLR------------------KLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLW-RYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJU5-1", "uniprot_id": "CNIH2_RAT", "id": "Q5BJU5-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLR------------------KLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLW-RYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35089-1", "uniprot_id": "CNIH2_MOUSE", "id": "O35089-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLR------------------KLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLW-RYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BL21-1", "uniprot_id": "CNIH2_DANRE", "id": "Q5BL21-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCAALIFFVIWQIIAFDELRTDFKNPIDQSNPTRARERILNIERICNLLR------------------RLVVPEYSIHGLFCLMFMCAGEWVTLGLNIPLLLYHLW-RFFHRPADGSEVMYDPVSVMNADILNYCQKESWCKLGFYLLSFFYYLYSMVYALVSF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6ZWS4-1", "uniprot_id": "CNIH3_MOUSE", "id": "Q6ZWS4-1", "name": "Protein cornichon homolog 3", "aln": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLR------------------KLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFW-RYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBE1-1", "uniprot_id": "CNIH3_HUMAN", "id": "Q8TBE1-1", "name": "Protein cornichon homolog 3", "aln": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLR------------------KLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFW-RYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D0Q0Y7-1", "uniprot_id": "CNIH3_RAT", "id": "D0Q0Y7-1", "name": "Protein cornichon homolog 3", "aln": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLR------------------KLVLPEYSIHSLFCVMFLCAQEWLTLGLNVPLLFYHFW-RYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32T7A5-1", "uniprot_id": "A0AB32T7A5_DANRE", "id": "A0AB32T7A5-1", "name": "", "aln": "-MFTFAAFCYMLSLVLCASLIFFAIWHITAFDELQADFKVPIDQGNPLHARERLRNIERICCLLRKQNWHSAVAKNCPVLPQLKLVLPEYSIHVLFCIMFLCAQEWLTVGLNIPLLFYNTWSRYFHSPTDTKELLYDPASVMNGDTLKFCQKEAWCKMSFFVLSFFYYLYCMIYTLVTS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35372-1", "uniprot_id": "CNIH1_MOUSE", "id": "O35372-1", "name": "Protein cornichon homolog 1", "aln": "MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNP----------------------------------LVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIW-RYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95406-1", "uniprot_id": "CNIH1_HUMAN", "id": "O95406-1", "name": "Protein cornichon homolog 1", "aln": "MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNP----------------------------------LVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIW-RYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LHJ2-1", "uniprot_id": "A0ABK0LHJ2_RAT", "id": "A0ABK0LHJ2-1", "name": "", "aln": "MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNP----------------------------------LVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIW-RYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49858-1", "uniprot_id": "CNI_DROME", "id": "P49858-1", "name": "Protein cornichon", "aln": "MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQCNSLNP----------------------------------LVLPEYLLHIFLNLLFLFCGEWFSLCINIPLIAYHIW-RYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGWIKLAVYLISFFYYIYGMVYSLIST------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38312-1", "uniprot_id": "ERV15_YEAST", "id": "P38312-1", "name": "ER-derived vesicles protein ERV15", "aln": "-MSGTGLSLFVTGLILNCLNSICQIYFTILYGDLEADYINSIELCKRVNR----------------------------------LSVPEAILQAFISALFLFNGYWFVFLLNVPVLAYNAS------KVYKKTHLLDATDIFR--KLGRCKIECFLKLGFYLLIFFFYFYRMVTALLENDANLIS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53173-1", "uniprot_id": "ERV14_YEAST", "id": "P53173-1", "name": "ER-derived vesicles protein ERV14", "aln": "----MGAWLFILAVVVNCINLFGQVHFTILYADLEADYINPIELCSKVNK----------------------------------LITPEAALHGALSLLFLLNGYWFVFLLNLPVLAYNLN------KIYNKVQLLDATEIFR--TLGKHKRESFLKLGFHLLMFFFYLYRMIMALIAESGDDF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: . : : : :*.:*: .*: . . * ** :: : :*: *. . :*:*:: *: *. ::. * * : *:...:: **:*:* *: *: ", "identical_positions": 21, "similar_positions": 43, "identity": "11.35%" }, { "cls_id": "homologset.agr.FB:FBgn0000346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QUL6-1", "uniprot_id": "NSF_RAT", "id": "Q9QUL6-1", "name": "Vesicle-fusing ATPase", "aln": "-----------------------MAGRTMQAARCPTDELSLSNCAVVNEKDY-QSGQHVMVRTSPNHKYIFTLRTHPSVVPGCIAFSLPQRKWAGLSIGQDIEVA---LYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNHQAFSVGQQLVFSFNDK-LFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKAST-KVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKG--KKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALMREEGASPLDFD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46460-1", "uniprot_id": "NSF_MOUSE", "id": "P46460-1", "name": "Vesicle-fusing ATPase", "aln": "-----------------------MAGRTMQAARCPTDELSLSNCAVVNEKDF-QSGQHVMVRTSPNHKYIFTLRTHPSVVPGCIAFSLPQRKWAGLSIGQDIEVA---LYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDK-LFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKAST-KVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKG--KKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALMREEGASPLDFD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46459-1", "uniprot_id": "NSF_HUMAN", "id": "P46459-1", "name": "Vesicle-fusing ATPase", "aln": "-----------------------MAGRSMQAARCPTDELSLTNCAVVNEKDF-QSGQHVIVRTSPNHRYTFTLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVS---LYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEK-LFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKAST-KVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKG--KKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PEX3-1", "uniprot_id": "A0A8M9PEX3_DANRE", "id": "A0A8M9PEX3-1", "name": "Vesicle-fusing ATPase", "aln": "-----------------------MATRTMQAARCPTDELSLTNCAVVSEKDL-QSGQHVTVRTTPTHKFVFTVKGHHSVLPGTIAFSLPQRKWAGLSIGQEIEVS---NYNFDKSRQCIGAMTIEIDFLQKKSTDSSPYDSDKMAAEFIQHFNNQSFSVGQQLVFSFCDK-LFGLLIKDIEAMDSSILKGEPASGKKQKIEVGLLVGNSQVIFEKSESSSLTLVGKAKTKEARQTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPDIVEQMGCKHVKGILLFGPPGCGKTLMARQIGKMLNAREPKIVNGPEILNKYVGESEANIRKLFADAEEEQKRLGANSGLHIIIFDELDAICKQRGTGASSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALMRPGRFEVKMEIGLPDEKGRVQILNIHTAKMREFKLLASDVDVKELAAETKNYSGAELEGLVRAAQSTAMNRHIKATS-TVEVDMERAEKLQVTRTDFMASLNNDIKPAFGTNQEDYSSYIMNGIIKWGDPVTRVLEDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKISEDSQFPFIKICSPDKMIGHSEISKCQAIKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKTPPHGRKLLIIGTTSRKDVLQEMEMLDAFSTTIHVQNISSGDHLVEALELLGSFTDAERTTIAQHVKG--KRVWIGIKKLLMLIEMSLQMDQEYRVSKFLSLLKDEGALDENNHIRI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46461-1", "uniprot_id": "NSF1_DROME", "id": "P46461-1", "name": "Vesicle-fusing ATPase 1", "aln": "------------------------MAYILKATKCPTDELSLTNRAIVNVGDFPEEIKYADISPAPGQHFIFALEKTVEVPSGYVGFSLVQRKWAMVSINQELEVR---PYRFDASSDVITCVSFETDFLQKKTVSQEPYDSDQMAKEFIMQFAGMALTVGQSLVFNFKDKKLLGLAVKSLEAIDPKSL-GEGKDTAMRNVRFGRILGNTVVQFEKAENSSLNLQGKSKGKVVRQSIINPDWDFGKMGIGGLDKEFNSIFRRAFASRVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLLTKIDGVDQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMREFNKINDDVDNKEIAALTKNFSGAELEGLVRAAQSSAMNRLIKADA-KVTVDPEAMEKLKVNRDDFLHSLEHDIKPAFGTAQEILDNMLARGVINWGAPVSNLLEDGMLYVQQAKAPESSGLVSVLVAGAPNSGKTALAAQLAKMSDFPFVKVCSPEDMVGYTESAKCLHIRKIFDDAYRSMLSCIVVDNVERLLDYGSIGPRYSNMTLQALLVLLKKQPPKGRKLLILCTSSRREVLEEMEMLTAFTSVLHVPNLSKPDHVLAVLENTDIFSKGEIQAIGKKMAG--KRVFIGIKKLLGLIDMARQTEQSQRAIKFLSKMEEEGGLDMVARQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18759-1", "uniprot_id": "SEC18_YEAST", "id": "P18759-1", "name": "Vesicular-fusion protein SEC18", "aln": "MFKIPGFGKAAANHTPPDMTNMDTRTRHLKVSNCPNNSYALANVAAVSPNDF-PNNIYIIIDN----LFVFTTRHSNDIPPGTIGFNGNQRTWGGWSLNQDVQAKAFDLFKYSGKQSYLGSIDIDISFRARGKAVSTVFDQDELAKQFVRCYESQIFSPTQYLIMEFQGH-FFDLKIRNVQAIDLGDIEPTSAVATG-IETKGILTKQTQINFFKGRDGLVNLKSSNSLRPRSNAVIRPDFKFEDLGVGGLDKEFTKIFRRAFASRIFPPSVIEKLGISHVKGLLLYGPPGTGKTLIARKIGTMLNAKEPKIVNGPEILSKYVGSSEENIRNLFKDAEAEYRAKGEESSLHIIIFDELDSVFKQRGSRGDGTGVGDNVVNQLLAKMDGVDQLNNILVIGMTNRKDLIDSALLRPGRFEVQVEIHLPDEKGRLQIFDIQTKKMRENNMMSDDVNLAELAALTKNFSGAEIEGLVKSASSFAINKTVNIGKGATKLNTKDIAKLKVTREDFLNALN-DVTPAFGISEEDLKTCVEGGMMLYSERVNSILKNGARYVRQVRESDKSRLVSLLIHGPAGSGKTALAAEIALKSGFPFIRLISPNELSGMSESAKIAYIDNTFRDAYKSPLNILVIDSLETLVDWVPIGPRFSNNILQMLKVALKRKPPQDRRLLIMTTTSAYSVLQQMDILSCFDNEIAVPNMTNLDELNNVMIESNFLDDAGRVKVINELSRSCPNFNVGIKKTLTNIETARHDEDP--VNELVELMTQSA----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 268, "similar_positions": 252, "identity": "34.45%" }, { "cls_id": "homologset.agr.FB:FBgn0000352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7M6Z5-1", "uniprot_id": "KIF27_RAT", "id": "Q7M6Z5-1", "name": "Kinesin-like protein KIF27", "aln": "-------------------------------------------MEEIPIKVAVRIRPLLCKEVLHN----------------------------HQVCVRDIPKTQ--------------------QIIIGRDRVFTFDFVFGKNSTQDEVYSTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIG-GGHVASVVDGQKGIIPRAIQEIFQSISGNPNIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDE-KGNTVIVGAKECQVDSVEDVMGLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVGKSAEATEDGEWCSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP-------RRKSSHVPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPQADRMDEMEFEIKLLREALQSHQASISQTSQTASENVPDQNRIHSLEEQIAQLQEECLGYQDCIEQAFAFLVDLKDAVRLNQKQQHKLQQWFSRTQEVRKAVLTPLPGNQSIGNLEEGPQHVTVLQLKRELKKYQCALAADQVVFTQKELELEELRRQMQLMAQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELAKRSSSMPTSTKESCGDGPDARAPEKRPHTAPFDSHWGHY--VYIPSRQDFKKVCSSSPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQE----------KPRVRSRSHSWVKKPGSVCSLVEMSDTQAECQRSYLGNGDLKMESLQESQELNLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGDNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELEGKDLSDVALKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRASELEQNVDHLKYQKVQLQRRLREESEKKKQLDAEVKRDQQKLKELQLNAGQGE-GLHPKAEDTDAFNLNRRKGPFR---SVDQLQKLDEQRKWLDEEVEKVLSQRQELEMLEEELKKREAIVSKKEALLQEKSHLENKKLRSSQALSTDSLKISARLNLLDQELSEKSLLLENSPTEEKVKISEQVQALQREREQLQRQRNSVDEKLRHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQNRQSSLKSSFQNLSQSESNVLEKLVCLNIAEIRAILFKYFNKVINLREAERKQQLQNKEMKMKVLERDNMVHELESALEYLRLQCDRRLTLQQKEHEQKMQLLLHHFKDQDGEGIIETLNKYEDKIQQLEKDLYFYKKTSRDLKKRLKDPVQGAVQWQRTLTEHHDAGDGVLNPEEAAVLSEELKWASRTENTKLNGREKEVDNSSSSLKTPPLTQQILEDGPDSLPVCGSLAPSSGQLQSSADKTEAH--AFTQSQSPPPPQLQPVRSIAQLQGVKPVKVCRRELRQISALELTLRRSSLGAGVRSVTADSLEEPEES-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M6Z4-1", "uniprot_id": "KIF27_MOUSE", "id": "Q7M6Z4-1", "name": "Kinesin-like protein KIF27", "aln": "-------------------------------------------MEEIPIKVAVRIRPLLCKEVLHN----------------------------HQVCVRDIPNTQ--------------------QIIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIG-GGHVASVVEGQKGIIPRAIQEIFQSISENPSIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDE-KGNTVIVGAKECQVESVEDVMSLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVEKNAEAAENGEWYSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP-------RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPALNISPQADRMDEMEFEIKLLREALQSHQASISQASQASSENVPDQNRIHSLEEQVAQLQEECLGYQDCIEQAFAFLVDLKDAVKLNQKQQHKLQEWFSRTQEVRKAVLTPLPGNQGIGNLEEGPQHLTVLQLKRELKKYQCALAADQVVFTQKDLELEELRTQVQLMMQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSAELAKRSLSVPTSAKESCGDGPDARASEKRPHTAPFESHWGHY--VYIPSRQDFKKVCSSTPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQE----------KPRVRSRSHSWAKKPGSVCSLVELSDTQAESQRSYLGNGDLKMESLQESQEINLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGNNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELESKDLSDVALKVKLQKEFRKKMDAAKMRVQVLQKKQQDSKKLASLSIQNEKRASELEHNVDHLKYQKVQLQRRLREEGEKKKQLDAEIKRDQQKIKELQLKAGQGE-GLNPKAEDQDGFNLNRRKSPFR---SGDQFQKLDEQRKWLDEEVEKVLSQRQELEMLEEDLKKREAIVSKKEALLQEKSLLENKKLRSSQALSTDGLKISARLNLLDQELSEKSLQLESSPTEEKMKISEQVQALQRERDQLQRQRNSVDERLKHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQSRQNSLKASFQNLSQSEANVLEKLVCLNITEIRAILFKYFNKVINLRETERKQQLQNKEMKMKVLERDNVVHELESALEHLRLQCDRRLTLQQKEHEQKMQLLLQHFKDQDGDSIIETLKNYEDKIQQLEKDLYFYKKTSRDLKKRLKDPAQGAAQWQRTLTEHHDAGDGVLNPEETTVLSEELKWASRTENTKLNGSEREVDNSSSSLKTQPLTQQIPEDGPDSLPARSSIAPSSGQLQSIADKTEAR--PFTHSQSPVPHQFQPVRSIGPLQGVKPVKLCRRELRQISAMELSLRRCSLGAGGRSMTADSLEDPEEN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VH2-1", "uniprot_id": "KIF27_HUMAN", "id": "Q86VH2-1", "name": "Kinesin-like protein KIF27", "aln": "-------------------------------------------MEEIPVKVAVRIRPLLCKEALHN----------------------------HQVCVRVIPNSQ--------------------QVIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIG-GGHIASVVEGQKGIIPRAIQEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDE-KGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP-------RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHY--IYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQE----------KSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEE-GLKPKAEDLDACNLKRRKGSFG---SIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNENKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGVGIGSMAADSIEVSRKPRDLKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LGI9-1", "uniprot_id": "A0ABK0LGI9_RAT", "id": "A0ABK0LGI9-1", "name": "", "aln": "---------------------------------MGLEAQKLSGAEEAPVRVALRVRPLLPKELLHG----------------------------HQSCLQVEPERG--------------------RITLGRDRHFGFHVVLGEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMG-EASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLELYKEEFRDLLEVGTASRDIQLREDD-RGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHFNRLSSRSHTVFTVTLEQRGRAPTRLPRP--GAGHLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSTLLALGNVISALGDP-------QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERVP--EEQAAGARGPP--RHRSE---TRIIHRGRRVLCPGVGSAAVAPGLGTECARCRARTSAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGER-SALSSASGPD--SGIESAPADDQAAQG-----------TSGRKGD-EGAQQLLILQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQ---EEMVELRLRLELAQPGWGAPGLLQGLSPGSFVPRPHTAPLGGAHTHMTGTMPRTCLPGEEVSSEQQVANGKEAKAELLAQVDKLGSASSTTSEEE-------EEEEEEPPRR-----TLHLRRNGISNWSQRAGVRPGSPPDRKGPEVCPEEPAAAIPAPQAVGGSKAPGQTRQAPAAMAS-EWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAERVRGELCEGQRQLRELEGREPQDASERSRLQ-EFRKRVAAAQSQVQVLREKKQATERLVSLSAQSETRLQELERNVQLMRRQQGQLQRRLREETEQKRRLETEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRNRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELRKREVILAKKEALMQEKTGLESKRMRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSALNQQQIRGEIDTLRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNVQLLLQQGRDHLGEGLADSKRQYEARIQALEKELGRHMWINQELKQKLSAGN----------------TAGQSRGCERRSHCLENRQGLGNEDGPHVAAQEPLWPSSLLEGAPRVWDESRDLVHAPLPLTWKRSSLCSE-QGSSEEPRAR----ETTEPPVGRVLP--------MGEVSLSWN---FGPLPKPRWEPRR---------TSPGMIDVRKNPL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7ZNG0-1", "uniprot_id": "KIF7_MOUSE", "id": "B7ZNG0-1", "name": "Kinesin-like protein KIF7", "aln": "---------------------------------MGLEAQRLPGAEEAPVRVALRVRPLLPKELLHG----------------------------HQSCLRVEPERG--------------------RITLGRDRHFGFHVVLGEDTGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMG-EASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLELYKEEFRDLLEVGTASRDIQLREDD-RGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHFNRLSSRSHTVFTVTLEQRGRTPSRLPRP--AAGHLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSTLLALGNVISALGDP-------QRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWHPEAERVP--EEQAAGARGPP--RHRSE---TRIIHRGRRVPCPAVGSAAVAAGLGAECARCRARTSAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGER-STLSSASGPD--SGIESAPAEDQAAQG-----------TSGRKGD-EGTQQLLTLQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQ---EEMVELRLRLELAQPGWGAPGLLQGLPPGSFVPRPHTAPLGGAHTHMLGMMPSTCLPGEEVSSEQQVVSGKEVKAEVLAQADKLRSASSTTSEEEGEEEEEEEEEEEEPPRR-----TLYLRRNGISNWSQRAGLSPGSPPDRKGPEVCPEEPAAAIPAPQAVGSGKVPVQTRQAPAAMAS-EWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAERVRAELCEGQRQLRELEGREPQDASERSRLQ-EFRKRVAAAQSQVQVLKEKKQATERLVSLSAQSETRLQELERNVQLMRRQQGQLQRRLREETEQKRRLETEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELRKREVILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQNQQQIRGEIDTLRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNVQLLLQQGRDHLGEGLADSKRQYEARIHALEKELGRHMWINQELKQKLSAGS----------------TAGQSQGCERRSLCLENRQCLGNEDGLHPAAPEPLWQSSLLEGVSRVWDESRDLVHAPLPLTWKRSSLCSE-QGSSEESRVR----ETTEPPVGRVLP--------MGEVGLSWN---FGPLPKPRWEPRR---------TSPGMIDVRKNPL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58G59-1", "uniprot_id": "KIF7_DANRE", "id": "Q58G59-1", "name": "Kinesin-like protein kif7", "aln": "---------------------------------MSPKGVGHSKVEESAVQVAVRVRPLLPKEILHS----------------------------HESCITSDPEER--------------------RVTLGNDRHFHCDFVFEDGSTQEEVYTNCVQPLIEAFFHGFNATVSAYGQTGSGKTYTIG-EASISAFRDDEQGIIPRAVAEIFKLLDENDLIDFSVRVSYMEVYKEVFRDLLEVETASKDIHIREDE-RGNVVLCGVKECEVEGLDEVLSLLESGKTARHTGATQMNPHSSRSHTIFTVLMEQR-RGGSRAAN---GSVQILSSKFHFVDLAGSERILKTGNTGERLKESIQINSGLLVLGNVIGALGDP-------KRKGTHIPYRDSKITRILKDSLGGNAKTLMIACISPSSSDFDESLNTLNYAKRARNIQNRATVNCRGEPDRIEGLELQIKALRRALENRQRSE---TRIIARSDPEKRLRPFEVDVRK-LQAESAHYRTCTDSAYRLLTELQGEGTLNAGQILRVKEWLCGVEEER-SGLTSASGLD--SGIESSSTEDSTALKRRQAVLNNQDLVKEDWRG-EREDYTSQLQAQIQQLEQENTDFLVALEDAMEQYKQQSDKLQEQQ---DLIAELHS--LLAQP--GGAGFLH------LKQRPHTAPIN-SLLQTPDRLTPPCDSDVGRSLARQLDVGASVDSSSYSEQTQWDGTHGNTHCESSRKLNRDEDGHMQTTRDKRKSINVTWTKKDIAIPQGPFGGTRTALPQTLGLCHPLGMQFNRRTSNSSIGESSVWESVRGFGGEFCS-DRGLLQAQQKIRELSITIRMKEELIKELVKTGKDAQAMNRQYSRKISELEAEAEQARVELTEAQKQLQELEVQGGRDAVDRSKAQ-ECRRKIAAAQSKVQVLKQKQRDTAQLASLSAQSERRVQELERNVQNMKQQQDLLQRRLREESQQKRRLETEMQKGKHRVKELEIKNEQQQKILRIKTEEIAAFQRQRRSGSNGSVVSLEEQQKIEEQKRWLDEEMEKVLDQRRGLEDLEGELTKREEILAKKEALLWERSGLESKKLRSSQALSQDLLTLSSRIESLERELTERNGLLRSGSAQDSQQIRQEISNLRQEKELLLKQRVELDDKLRQGNLLSPEEERTLFQLDEAIEALDAAIEYKNEAITQRQRQLRASGSMLTQWEMNLMAKLTYLSASETRALLCKYFDKVVSLREEERRLQMALAELELRVEEQQNLVGWLEAALERQQLEADRRLTQQQKEHERNIQLLLQQCREQMDEGLAGRLRQYEGLIHNLSKELNFCKIANQELNIKLREMC----------------GPVNLTGEQCKGLNCDSLLLAG----AQSRVAEDVKPIIDAERVQKSREEMREPVNAPLPATWRRSSLPTEDQYTMEELRQR----AACELPNNRIVQ--------PGMNSTHWSGSTSLPVTRPRREPRRSSLNTAPLYSSSAIIDVRRNPV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O16844-1", "uniprot_id": "COS_DROME", "id": "O16844-1", "name": "Kinesin-like protein costa", "aln": "MEIPIQVAVRIFPHRELKDLLRSFGPTEPKKDAQAVDEGADSKDSEAQVPAAEKDNPSISETDPNGNAEQDSAADSKTIPDANGNDSGQKDYPDSAYCVQAIPISASALGLPSALPGGDPMDSIAAGLIQVGPHTVPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQLCVRDIFSHISLHPERTYAINVGFVEICGGDVCDLLGMG-----------------------NIHCTNVDAVFHWLQVGLSARQS---------LPAHTLFTLTLEQQWVSKE-------GLLQHRLSTASFSDLCGTERCGDQ-------PPGRPLDAGLCMLEQVISTLTDPG----LMYGVNGNIPYGQTTLTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNTYSDDNTMIVQPAEP-------------------VPESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEKEQIEEWLFLKQECEECLSS--------------------------------------------TEAMRQQKQLVPILEAEEPEDVNSEAANSESPNSDNENDTDNE-------------------------------------SHRPDLDDKIESLMEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIEAQPPEENGDDRKVSIGSRRRSVQPGASLS----------TAELAMLNRVASQQPPPPIDPESVVDPLESSSGEGIRQAALAAAAATAPIEQLQKKLRKLVAEIEGKQRQLREIEETIQVKQNIIAELVKNSDTRSHAKQRFHKKRAKLEAECDKAKKQLGKALVQGRDQS-------------------EIERWTTIIGHLERRLEDLSSMKHIAGESGQKVKKLQQSVGESRKQADDLQKKLRKECKLRCQMEAELAK----------------------------------------------LRESRETGKELVKAQGSPEQQGRQLKAVQARITHLNHILREKSDNLEEQPGPE-----------------------------------------QQETLRHEIRNLRGTRDLLLEERCHLDRKLKRDKVLTQKEERKLLECDEAIEAIDAAIEFKNEMITGHRSIDTSDRIQREKGEQMLMARLNRLSTEEMRTLLYKYFTKVIDLRDSSRKLELQLVQLERERDAWEWKERVLSNAVRQARLEGERNAVLLQRQHEMKLTLMLRHMAEETSASSASYG---ERALAPACVAPPVQASSDFDYDHFYKGGG------------------NPSKALIKAPKPMPTGSALDKYKDKEQRSGRNIFAKFHVLTRYASAAAAGSSGSTAEESTALIESTTTATATTTSTTTTG----AVGKVKDKALVS--------------------FRPEQLKRLMPAPTATKVTRQKNKIIIQDASRRN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32364-1", "uniprot_id": "SMY1_YEAST", "id": "P32364-1", "name": "Kinesin-related protein SMY1", "aln": "-----------------------MHWNIISKEQSSSSVSLPTLDSSEPCHIEVILRAIPEKGLQNN-----------------------------ESTFKIDPYENTVLFRTN---------NPLHETTKETHSTFQFDKVFDANATQEDVQKFLVHPIINDVLNGYNGTVITYGPSFSGKSYSLIGSKESEGILPN----ICKTLFDTLEKNEETKGDSFSVSVLAFEIYMEKTYDLLVPLPERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQNVGNRMACGDKTERSRSHLVFQLHVEQRNRKDDILKN----------SSLYLVDLHGAEKFDKRTESTLSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQLTEVLKDSLGGNRKTKVILTCFLSN--VPTTLSTLEFGDSIRQINNKVTDNTTGLN-------------------------------------------------------------------------------------------------------------------------------------------------LKKKMDLFIQDMKIKDDNYVAQINILKAEIDSLKSLHNKSLPED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEKKMLENTKKENIKLKLQLDSITQLLSSSTNEDPNN--------RIDEEVSEILTKRCEQIAQLELS-----------------FDRQMNSNSKLQQELEYKKSKEEALESMNVRLLEQIQLQEREIQELLTTNAILKGELETHTKLT-------------------------------------------------------------------------------------------------------------------------------------------------------ETRSERIKSLESSVKELSLNKSAIPSPRRGS--MSSSSGNTMLHIEEGSEISNSPWSANTSSKPLVWGARKVSSS-------------SIATTGSQESFVARPFKKGLNLHSIKVTSSTPKSPSSGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. : :. . * . .: .: *: * : *:: .:.*::.:* :** .**:*:: . . : : : :. . : * .*: *** . . : :: . : :* :* : : * *. : ** *:*: . :: : * :.: :* . .* :: :* :****:** :* :* . . :*..*::. : :.* * : : . . :. :: .: :: .:::: : * :*: .. . . .:: : .. : : * . .: *. : : : . : . ::.: *: .*. . : .: *. . * .: : : . :: .. . ::. :*. * ::. . ... . . . .::: : * * : *:. . . . ", "identical_positions": 53, "similar_positions": 174, "identity": "3.49%" }, { "cls_id": "homologset.agr.FB:FBgn0000370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES19-1", "uniprot_id": "ATF4_RAT", "id": "Q9ES19-1", "name": "Cyclic AMP-dependent transcription factor ATF-4", "aln": "--------------------MTEMSFLNSEVLAGDLMSPFDQSGLGA--EESLGLLDDYLEVAKHFKPHGFSSD--KAGSSEWLAMD-GLVSASDTGKEDAFSG--TDWMLEKMDLKEFDFDALFRMDDLETMP-------------------------------------------------DELLATLDDTCDLFAPLVQETNKEPPQTVNPIGH--LPESVIKVDQAAPFTFLQPLPCSP------------------GFLSSTPDHSFSLELGSEVDISEGDRKPDSAAYITLTPQCVKEEDTPSDSDSGICMSPESYLGSPQHSPSTSRAPPDSLPSPGVPRGS-RPKPY---DPPG-VSVTAKVK-TEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRVP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06507-1", "uniprot_id": "ATF4_MOUSE", "id": "Q06507-1", "name": "Cyclic AMP-dependent transcription factor ATF-4", "aln": "--------------------MTEMSFLNSEVLAGDLMSPFDQSGLGA--EESLGLLDDYLEVAKHLKPHGFSSD--KAGSSEWPAMDDGLASASDTGKEDAFSG--TDWMLEKMDLKEFDFDALFRMDDLETMP-------------------------------------------------DELLTTLDDTCDLFAPLVQETNKEPPQTVNPIGH--LPESLIKVDQVAPFTFLQPFPCSP------------------GVLSSTPEHSFSLELGSEVDISEGDRKPDSAAYITLIPPCVKEEDTPSDNDSGICMSPESYLGSPQHSPSTSRAPPDNLPSPGGSRGSPRPKPY---DPPG-VSLTAKVK-TEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRVP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18848-1", "uniprot_id": "ATF4_HUMAN", "id": "P18848-1", "name": "Cyclic AMP-dependent transcription factor ATF-4", "aln": "--------------------MTEMSFLSSEVLVGDLMSPFDQSGLGA--EESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVD-GLVSPSNNSKEDAFSG--TDWMLEKMDLKEFDLDALLGIDDLETMP-------------------------------------------------DDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGH--LPESLTKPDQVAPFTFLQPLPLSP------------------GVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPY---DPPGEKMVAAKVK-GEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW59-1", "uniprot_id": "ATF4_DANRE", "id": "Q6NW59-1", "name": "Cyclic AMP-dependent transcription factor ATF-4", "aln": "--------------MSLCVGDAGALLLGPWPLTADPQGPLLDQDEES--SVLEGSWSPSSSSLSSFSPPASGDAPSELLSLSWQPSDVLLTEQSTAG--DVFPG--MDWMTEKLDLNDFDLDSLIGSCDSEDSPGS----------------------------------------------PEDLLACLDSSMDLDLDSLPFGSADLDLPLGLDLP--LPEEIKS----EPLSPAPSVPSPP------------------EEAPQDEHTEVPVLHPAGIMLS----LSPSHIVVLLTPKEEQNISDCSDSDSGISVS-----GSPAHQSDLEPSSRAKPYS--------RPDPE---ASPALKGRVKTSSGAPKVEKKLKKMEQNKTAATRYRQKKRVEQESLNSECSELEKKNRELSEKADSLSREIQYLRDLLEEMRTAKQRKSKR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P788-1", "uniprot_id": "ATF5_RAT", "id": "Q6P788-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTER-----------VDFTALLPLEAPLPPGTLPPPS-------------------------------------------------------PAPPDLEAMASLLKKE--------------LEQMEDFFLDAPLLPPP-----------------------------SPPPPPPP--APSLPLPLP---------LPTFDLPQPPTLDTLDLLAVYCRS----EAGPGDSGLTTLPVPQQPPPLAPLPSLSRPAPY---PSPA----STR------GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70191-1", "uniprot_id": "ATF5_MOUSE", "id": "O70191-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTER-----------VDFTALLPLEAPLPPGTLPPPS-------------------------------------------------------PAPPDLEAMASLLKKE--------------LEQMEDFFLDAPLLPPP-----------------------------SPPPPPPPAAAPSLPLPLP---------LPTFDLPQPPTLDTLDLLAVYCRS----EAGPGDSGLSTLPVPQQPPPLAPLPSPARPAPY---PSPA----STR------GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2D1-1", "uniprot_id": "ATF5_HUMAN", "id": "Q9Y2D1-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTER-----------VDFTALLPLEPPLPPGTLPQPS-------------------------------------------------------PTPPDLEAMASLLKKE--------------LEQMEDFFLDAPPLPPP-----------------------------SPPPLPPPPLPPAPSLPLS---------LPSFDLPQPPVLDTLDLLAIYCRN----EAGQEEVGMPPLPPPQQPPPPSP-PQPSRLAPY---PHPA----TTR------GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P756-1", "uniprot_id": "A0A8M9P756_DANRE", "id": "A0A8M9P756-1", "name": "", "aln": "MAYNWMTKTFDTYPNSTSTESSPGSSIPPSPLEHDVQMPSDLEVMTNLLKEELAQLEDYYLYESAPMKLEKWQKCDKSLQAMATQSYYQLPCASYNVNQSETNPRLVSLAAGELDLRGFCGGSVNRPKMSRPAPYSYIRTHCNSQRISSNGCKDVEVFEKETWTFKGTHSGYAELAFDQCSVDKSFGKNHGSAKKVRECAILLKEEEKSCFSEDVFY--RAEMMRSYDLAGSLEPHHRRESQCHGMKMLGHDGIAMPILQCAENESCPPPYKQSDVAECYFHQITANLEPYHGFMNEIDQPIRTDIQNNDYLHHECLGDQSFECLSGDSVGSSLELPVQKPLQRSRESQCVFKPD---VKVG----VERNH----GERKQKKRDQNKSAAHRYRQRKRAEQDCLEEELHGLEGRNRELRDKAESVEREIQYVKDLLIEVYKARSQRLKEDSSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VID3-1", "uniprot_id": "Q9VID3_DROME", "id": "Q9VID3-1", "name": "", "aln": "--------MDATFHQTMESLQLPKELYWDLKMEPQSPTSVLGSDLFPLTDSNDTEWLYDDNFANGITLIGDDEALTLEEVASLQLLSDEEMVVEIFDLKDEECLLDQKATLNCIDYDSNSFQPNINVITQAIVPAN-----------------------------------------------KVQFGASSDAASLPSAADYQLNDGPSLILQQLTPPQSPPQFDAYKQAGDAQPKPVLVKAEQKVQCYTP---------DVTHAASATPFNFTNWVGGSEIARENQLVDDIVNMRAKELELSTNWQQLNEDCESQASSSLDSRSTGSGVCSSIADADEDWVPELISSSSSPAPTTIEQSASQPKKRTRTYGRGVEDRKIRKKEQNKNAATRYRQKKKLEMENVLGEEHVLSKENEQLRRTLQERHNEMRYLRQLIREFYHERKR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* * . .: . . : : . . * . ::* :* :***.** ****:*: * : : * *. .*. * :. .*::*:::*: *. : : ", "identical_positions": 24, "similar_positions": 37, "identity": "5.3%" }, { "cls_id": "homologset.agr.FB:FBgn0000376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96RY5-1", "uniprot_id": "CRML_HUMAN", "id": "Q96RY5-1", "name": "Protein cramped-like", "aln": "-----------------MTVKLGDGGSGEDGLKKLGKR--------AADEESLEG--EGAGGADAAEESSGTKRDEKTPRAGADGPPAPPGAPQAPSPPQGSP--QDQHHFLRSSVRPQSKRPRKDPPSAVGSGNAGGSGPRGKGAEGGGSSSGNVSGVAPAAPAGGSRSSSRNLGSSGGEKEEG---KKVRRQWESWSTEDKNTFFEGLYEHGKDFEAIQNNIALKYKKK-GKPASMVKNKEQVRHFYYRTWHKITKYIDFDHVFSRGLKKSSQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKLCDPDGLSDEEDQKPVRLPLKVPIELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIEFLKQKWALHEVRVRKTLEERQLQDSCSAPMQEKVTLHLFPGENCTLTPLPGVARVVHSKAFCTVHWQEGGRCKQSAKDAHVLPPAQILGIQSGQGTARGQVKCPRSGAEGKGVGRPPPAADALQSSGESSPESAPGEGAALSLSSPDAPDRPPPRHQDTGPCLEKTP----AEGRDSPTREPGALPCACGQLPDLEDELSLLDPLPRYLKSCQDLIVPEQCRCADTRPGSEQPPLGGAASPEVLAPVSKEAADLAPTGPSPRPG------PGLLLDVCTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQTSESLTLAEVYLMMGKPSKLQLEYDWL---GPGRQDPRPG-------SLPTALHKQRLLSCLLKLISTEVNPKLALEANTISTASVRPAQEEQSMTPPGKVVTVSSRSPRCPRNQASLRSSKTFPPSSAPCSSGLRNPPRPLLVPGPSSTGSNDSDGGLFAVPTTLPPNS-RHGKLFSPSKEAELTFRQHLNSISMQSDFFLPKPRKLRNRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSSVTGRGSFRPIQSSLT-KAALSRPIVPKVLPPQATSHLASAIDLAATSAGILSGNPLPALDTEGLSGISPLSSDEVTGAISGQDSTGTHQDGDTLPTVGGS-DPFVSIPSRPEQEPVADSFQGSSVLSLSELPKAPLQNGLSIPLSSSESSSTRLSPPDVSALLDISLPGPPEDALSQGEPATHISDSIIEIAISSGQYGEGVPLSPAKLNGSDSSKSLPSPSSSPQPHWIASPTHDPQWYPSDSTDSSLSSLFASFISPEKSRKMLPTPIGTNSGTSLLGPSLLDGNSRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSIAEPGRREALFDGGGGGPAVSDLSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PG95-1", "uniprot_id": "CRML_MOUSE", "id": "Q6PG95-1", "name": "Protein cramped-like", "aln": "-----------------MTVKLGDAGSGEEGLKKLGKR--------TADEESLDG--EGPGGADAAD-SSSTKRDGQTPRA--SGAPAPPRGLPTPSPPQGSP--QDQHHFLRSSVRPQSKRPRKDAPCALGSGGASGSGPRGKGSDGGASSSGNVSGATPATPAGGSRSSSRNIGSSGPEKEEG---KKVRRQWESWSTEDKNTFFEGLYEHGKDFEAIQNNIALKYKKK-GKPASMVKNKEQVRHFYYRTWHKITKYIDFDNVFSRGLKKSSQELYGLICYGELRKKIGGCMDDKNATKLNELIQVGATTVRYKGRNLRIKAPMCRALKKLCDPDGLSDEEDQKPVRLPLKVPVELQPRNNHAWARVQSLAQNPRLRMIVELHRKVSSLIEFLKQKWALHEVRIRKTLEERQLQGSSTVQTQEKVALHLFPGENCTLTPLPGVARVVHSKAFCTVHWQEGGRCKQGTKDIHSLPPAQILGIQSGQGIARGQLKCQRSSAEGKGGGRLLPTADASQSSGESSPESAPAEGAAPSLSSPDAPDRPHG-LQDSGPHLEKTPVTALAVGRDSPIQESGALPCPCGQPPDLEDELSLLDPFPRYLKSCQDLIIPEQCRRADTRSGREHPPLGSVASPETLTPSSGAVADSAPPGLDPQPGTDHQPDTRLQSDICTKELANASSEESQEKGSPSEHLSSQGQPATRPSKEVPASQLAQQLREEGWSLQTSESLTLAEVYLMMGKPTKLQLEYDWLAVLGPESQAPTAQGQTALSRSSPSALHQQRLLSCLLRLISTEVHPKMAFEANTASTASVRPTQEEQSTTPPGKVVTINSRSPRCSRNPSTLRSNKTFPSASAPCSPGLRNPPRPLLVAGPSSTGSSDSDGGLFAVPTTLPPNS-RHGKLFSPSKEAELTFRQHLDSISIQSDFFSPKPKKLRKRHLRKPLVVQRTLLPRPSENQSHNVCSFSILSNSPIAGRGWFRPIQSSLT-KAALSRPIVPKVLPSQATSHLPSAIDLAAQSAGIIPGSPLPILDTDGSSGISPLSSEQATTAISGQGDTGPHQNRDPVTAVRGTNDPFISVT-RPEQEPMTDGFQGSPALTLPELSKANLQNGLSIPLPSSESSSTRLSPPNVSALLDISLPGPPEDVLSQGEPATQISDSIIEIAISSGQYSEGVPLSPAKLNGSDSSKSLPSPSSSPQPNWIASPTHDPQWYPSDSADSSLSSLFASFISPEKSRKMLPTTVGANSGTSLLGPSLLDGNSRDSFVSRSLADVAEVVDSQLVCMMNENSIDYISRFNDLAQELSITEPGRREVLFDGGGGGNPVGDLSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RIJ0-1", "uniprot_id": "A0A8M1RIJ0_DANRE", "id": "A0A8M1RIJ0-1", "name": "Protein cramped-like", "aln": "MVKRKKTPSASEELENGMTVGQG-GGSGVEGPSKPDRKPEGGEDGESADQASEETSTKRVGEETLNPSSTASPGSAPTPSTQTSSPPGPQVNPTALSPGLAVPNNQDQHHFLRSSVRPPSKRIRKDASSPALNGHG---GAKAKGAEAGPSVCVAAAAGSAGGSGAGGTSRSAPKGQGPAEKEEGGSQKRVRRQWESWSTEDKNSFFEGLYEHGKDFEAIQNNIALKYKKK-GKPASMVKNKEQVRHFYYRTWHKISKHIDFNNVYSRVLKKSSQELYGLICYAELRKKVGGLMDDKNVAKLNELIQQGATTVRSKGRNLRIKAPMCRALKKICDPDGVSDEEDQKPVRLPLKVAVELQPRSNHSWARVQSLAHNPRLRMVIELHRKVSTLIEFLKQKWAVQDQRIRKSLAEREALDG-LAQSSESEELFLFPAESSTVTALPGVARVVHSKASCTVHWQESGRGRTGIRD---LPAAHILGIQPARG---------KSGKPGPVGG------DSKRTDGHPVEGSDSSSTSAAGLETSANPN----------------------VNTTSPVSPTITSLLPIGPEG-------------------------NPAGSAEQEPASQTQTDAGGGDKQIETVTQGDPASSE--GRTDEPG--------------------------TAGGVASEKALPQSEAQGRVEEVVGTGRSPQQIREEGWSSQVSENVTLAELYLMLGKPGKLQLEYEWQ-------SKPNPP---------SVLPNSQNVLRCLLRLVSSEVNPKPTPEVCSVGTSPLKSGQEESSVTPPGRTPAGANRSPSWGRQQHAARSKILLN------NPGGRNLPRSLLASG------GDSEG--FAVPTTLPPNSSRQSRMFSPNKEAELAFRQQLDSIS--SDIFSKQRKIGRGRPLRKPLVVQRTLLPRTAGDTSPHVCSFSILSNSSATGTGSFRPIQTRLAPNRQPSSKASSSTGSPAPVTQLSSAIDLAAKSAGIIPGSPCREVEAPSID-----------------------------KAIVESEDAMGSAPAAPEMEPDILD---------QEPSEESLQNGVSPPSPGGGES--LLAPPSVASLLDISLPGPPEESLPSGEPQTQISDSIIELAINS-HYGDGSLLSPPKLNGSDRSKLLPSSCDS----WMPSPTHDPQWYPNDSTDSSLGCLLSSLASPDKTR---RTALPPSSSTALLGPSLLDSNSHDCFQSRGLPDAAEV-DTQLACMMSESSVDYIARFNDLAQELSVTETTLP----------PPHGD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5BK20-1", "uniprot_id": "JUPI2_RAT", "id": "Q5BK20-1", "name": "Jupiter microtubule associated homolog 2", "aln": "-------------------------------------------------------------------MFRGADGQASKSGFRSMKPPGGESNDIFGSPEEGVP--SSKPHRMASNIFGPTEEPKNIPKRTN----------------------------PPGGKGSGIFDESTPVQTRQRLNPPG---------------GKTSDIFG---------SPVTATAPLAHPNK-PKDHVLLCE-------------------------------------GEDCKSDLKAATN------------------------------------------STPRGEQGEKGSSTEAEPAKIPEPIPTVDSHEPR----LGPRPRSHNKVLNPPGGKSSISFY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76906-1", "uniprot_id": "CRM_DROME", "id": "O76906-1", "name": "Protein cramped", "aln": "--------------------------------------------------------MEELSKQPPPPPLTQPPPPSSSVSIEEPLPNGKGGGAVVVNSIAKLP----EEELLGSVTMHNCPGTRASARVIQKMKQD-----------------QTRPMTPPPSEREPNKKEEKAAQKTPSQLKTG-------SGKTTWTNVERNCFFDALNEFGKDFEAVANCINAKLKRRNANSDYSFKTKDQVRQHYYQTHHKICKYVR----FSEELKKPAQELYTLINYGEMRRKLQ-FLTEKHFMKLKQLVYQGQITVRCKGKNIRIKTPSCKALRRLNQLDDSLED-----IRLPSKVEVLVTPANMEAFGRVQSLAQNPRGRIIVPLHKKLISFIKTFEYKWRSANQRLHEEKSAYFSSSLPSAASNNNN------NNNETEPLQPSVASLDPSMCFQPRPGVAIHRPLLSITAYLSSISICLTAYEERMG------FKVRSETLGNLAGMSVAANKRLRTESGSEKRSPETKKPKSSASPPLEKSLDDGPLEGN-----------LMKMENSSGDELGEEIHEFLGDILEAMQHPQAATIPALSATTGDTTNVAVALETSHDPVQQAYPANADLSNAMATSVLQTSCAAAPAPSTPVTG--------------------SLAAPSVARSKRKEAKEAAAAAQARNFKPLLSDDILKRIR-KGWTQANAADITIGDLYVVFGQDSKLELEYYWC------------------------------------EVDSSTAMASSILTINTVTPSSSSVGTQTGSAASNANQTGASSNCYVSASSNSSTSST---------------------------------------SLPYNPNDCDSVERVRAVTTSSVSNKLKHLLLVANLSERVRKRQCNCGHTCDRKRDLMTKAQQLAEATATGGVGGMVEGNFRTPMLPVRRPISNIDPVRQLSALTRQKISRQVLVQRRLLPPTSAGDRPYDLLSVRQLHSG-----------------------------------------------------------------------LFEPIDRVDGTSSAGISTSGSKPDCSMNAMTASQDQEPGDQGALEFLNDEATQVSARDMPNLDICVATNRTDVSSSLNEAAQDGSTTQSFFQGSMSP--MHLLRDSTSNARWLEDNINDFSLTSLLGHLDEIDATR-------------DILDP------------------------SSSMSVISESSVDFRHKFQEIAALLQQQEKD--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .. * : . : * : . .. . . * . . :* ..: .: : . .::: . : * *: : . . . *. .** : : : *. ", "identical_positions": 10, "similar_positions": 42, "identity": "0.75%" }, { "cls_id": "homologset.agr.FB:FBgn0000377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63155-1", "uniprot_id": "CRNL1_RAT", "id": "P63155-1", "name": "Crooked neck-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFG--------DEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEADTVREVYERAIANVPP--IQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASL-ELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPR----LDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQH-VKVWISFAQFELSSGKEGS------------------------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAAN-QPN-LKLLAMAKLWKKQQQEREA---------------------------------------AEQDPDKDIDESESSSF-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63154-1", "uniprot_id": "CRNL1_MOUSE", "id": "P63154-1", "name": "Crooked neck-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFG--------DEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEADTVREVYERAIANVPP--IQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASL-ELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPR----LDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQH-VKVWISFAQFELSSGKEGS------------------------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAAN-QPN-LKLLAMAKLWKKQQQEREA---------------------------------------AEQDPDKDIDESESSSF-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZJ0-1", "uniprot_id": "CRNL1_HUMAN", "id": "Q9BZJ0-1", "name": "Crooked neck-like protein 1", "aln": "MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCALDALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFG--------DEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPP--IQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASL-ELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPR----LDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQH-VKVWISFAQFELSSGKEGS------------------------LTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAAN-QPN-LKLLAMAKLWKKQQQEKED---------------------------------------AEHHPDEDVDESES----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803R7-1", "uniprot_id": "CRNL1_DANRE", "id": "Q803R7-1", "name": "Crooked neck-like protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDKEELNDYKLKKRKGFEDNIRKNRTVISNWIKYAQWEESLQEVQRSRSIYERALDVDHRNITLWLKYAEMEMKNRQVNHARNIWDRAITILPRVNQFWYKYTYMEEMLGNIAGCRQVFERWMEWEPEEQAWHSYINFELRYKEVDKARSIYENFVMVHPEVKNWIKYAHFEEKHGYVARGRKVFERAVEFFG--------EEQVSENLYVAFARFEEKQKEFERVRVIYKYALDRIPKQQAQELFKNYTVFEKRFGDRRGIEDVIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDADADTVREVYERAIANIPP--IQEKRHWRRYIYLWINYALYEELEVKDPERTRQVYKACL-ELIPHKKFTFAKIWLLYGQFEIRQKNLQNARRGLGTAIGKCPKNKLFKGYIELELQLREFDRCRKLYEKYLEFSPENCTTWIKFAELETILGDTDRSRAIFELAIGQPR----LDMPEVLWKSYIDFEIEQEEYDNTRGLYKRLLQRTQH-VKVWISYAQFELSIDTEDR------------------------VQRCRQVYEEANKGMQNCEEKEERLMLLESWRDYEEEFGSFTHKERVRKLLPEKVKKRRKITAEDGSDAGWEEYYDYIFPEDAAN-QPN-LKLLAMAKMWKKQQQQEEEDDDEEEDENDKEEQQVPEGKDAQESPEAEEQEPAAGGEQAEKEYDDRDDEDESSSSSSSDSESDEDQKDKTEHNKPDTEQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17886-1", "uniprot_id": "CRN_DROME", "id": "P17886-1", "name": "Protein crooked neck", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MERPQKMPKVAKVKNKAPAEVQITAEQLLREAKERDLEILPPPPKQKISDPAELADYQQRKRKTFEDNLRKNRMVVSHWIKYAQWEEQQQEIQRARSIWERALDNEHRNVTLWLKYAEMEMKNKQVNHARNLWDRAVTIMPRVNQFWYKYTYMEEMLENVAGARQVFERWMEWQPEEQAWQTYVNFELRYKEIDRAREIYERFVYVHPDVKNWIKFARFEESHGFIHGSRRVFERAVEFFG--------DDYIEERLFIAFARFEEGQKEHDRARIIYKYALDHLPKDRTQELFKAYTKHEKKYGDRAGIEDVIVSKRKYQYEQEVAANPTNYDAWFDYLRLIEAEGDRDQIRETYERAISNVPP--ANEKNFWRRYIYLWINYALYEELEAEDAERTRQIYKTCL-ELIPHKQFTFSKLWLLYAQFEIRCKELQRARKALGLAIGMCPRDKLFRGYIDLEIQLREFERCRMLYEKFLEFGPENCVTWMKFAELENLLGDTDRARAIFELAVQQPR----LDMPELLWKAYIDFEVALGETELARQLYERLLERTQH-VKVWMSFAKFEMGLSHGDSGPDAELN-----------------VQLARRIYERANEMLRQLGDKESRVLLLEAWRDFERDASDSQEMQKVMDKMPRRIKKRQKIVSDNGVEEGWEEVFDYIFPEDEMA-RPN-LKLLAAAKMWKTQKDNTVDD-------------------------------PPATAIASEPEPAADAAPADTTDSGD-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12309-1", "uniprot_id": "CLF1_YEAST", "id": "Q12309-1", "name": "Pre-mRNA-splicing factor CLF1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTLEPTAVDTHVSAEQILRDVYKKGQKARG-STNIDILDLEELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSLEPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPSN--QLLKAGLLDFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLIS-ESFPKQIMQTFEKAIVDSRPKELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEETYGTELDQETVKKRFPKVIKKVR---LQNGVEE---EFVDYIFPDDIDDDKPKPSKFLELAKKWKQEQAL------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :..:.:::***:**:. :: : ..: .* * ** :*: :**. :*. :::** :.:**:***:* . ::::*:***:**** : :.**::* : *:* : :*****: :**:: :***:::**** :** * *: *.:: :* . :* :**:::::**:* *: : .* **..:* .** ::.*:*:.:**: *. * *:. *:: .. .: .* :**::* *:*.:* :*: *::: ..: * * .**::** .**: * **: :** : *. :**:*: ** *:. :. . : :.:*:** : * .:: *:******:.* * *** ::. .:::: : ::****:***:*:*: *.:* ** .:: **: ** :** **: * *: **:**::*:**:* * :***::** *.: * ::.*** *** :* *.*: :*: : : :* : ** ** * : :* **.: *: .*: : *:.:* :: . .*:::*.* ::: :*: *: :**: :.:* . . : * . :*. :** : ::* : * *****:* :*: *:* ** ** :: ", "identical_positions": 209, "similar_positions": 235, "identity": "21.84%" }, { "cls_id": "homologset.agr.FB:FBgn0000382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29351-1", "uniprot_id": "PTN6_MOUSE", "id": "P29351-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "-----------------------MVR-WFHRDLSGPDAETLLKG------------RGVPGSFLARPSRKNQ----GDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLN-------------------------------------------------CSDPTS------------ERWYHGHISGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPG-SPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKN-----------------------------QLLGPDENSK-----------------------------------------------------------------------------------------------------------------TYIASQGCLD----ATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNSREHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAG----PIIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNITYPPAVRSAHAKASRT----------------------------------------SSKHKEEVYEN------------------------------------------------VHSKSKKEEKVKKQRSADKEKNKGSLKRK--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81718-1", "uniprot_id": "PTN6_RAT", "id": "P81718-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "----------------------MLSRGWFHRDLSGPDAETLLKG------------RGVPGSFLARPSRKNQ----GDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATSTELVEYYTQQQGILQDRDGTIIHLKYPLN-------------------------------------------------CSDPTS------------ERWYHGHMSGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAAPG-SPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEAKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKN-----------------------------QLLGPDENSK-----------------------------------------------------------------------------------------------------------------TYIASQGCLD----ATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNCKEHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAG----PIIVHCSAGIGRTGTIIVIDMLMESVSTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQRGQESEYGNITYPPALRSAHAKASRT----------------------------------------SSKHKEEVYEN------------------------------------------------VHSKNKKEEKVKKQRSADKEKNKGSLKRNISLTPCRGLRWADRDL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29350-1", "uniprot_id": "PTN6_HUMAN", "id": "P29350-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "-----------------------MVR-WFHRDLSGLDAETLLKG------------RGVHGSFLARPSRKNQ----GDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLN-------------------------------------------------CSDPTS------------ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPG-SPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKN-----------------------------QLLGPDENAK-----------------------------------------------------------------------------------------------------------------TYIASQGCLE----ATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAG----PIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRT----------------------------------------SSKHKEDVYEN------------------------------------------------LHTKNKREEKVKKQRSADKEKSKGSLKRK--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41499-2", "uniprot_id": "PTN11_RAT", "id": "P41499-2", "name": "Tyrosine-protein phosphatase non-receptor type 11", "aln": "----------------------MTSRRWFHPNITGVEAENLLLT------------RGVDGSFLARPSKSNP----GDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------------------------------------CADPTS------------ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDSKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMP-----------------------------EFETKCNNSKPK--------------------------------------------------------------------------------------------------------------KSYIATQGCLQ----NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDECALKEYGVMRVRNVRESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAG----PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLP----------------------------------------PCTPTPPCAE------------------------------------------------------MREDSARVYENVGLMQQQRSFR----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35235-2", "uniprot_id": "PTN11_MOUSE", "id": "P35235-2", "name": "Tyrosine-protein phosphatase non-receptor type 11", "aln": "----------------------MTSRRWFHPNITGVEAENLLLT------------RGVDGSFLARPSKSNP----GDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------------------------------------CADPTS------------ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMP-----------------------------EFETKCNNSKPK--------------------------------------------------------------------------------------------------------------KSYIATQGCLQ----NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAG----PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLP----------------------------------------PCTPTPPCAE------------------------------------------------------MREDSARVYENVGLMQQQRSFR----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06124-2", "uniprot_id": "PTN11_HUMAN", "id": "Q06124-2", "name": "Tyrosine-protein phosphatase non-receptor type 11", "aln": "----------------------MTSRRWFHPNITGVEAENLLLT------------RGVDGSFLARPSKSNP----GDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN-------------------------------------------------CADPTS------------ERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMP-----------------------------EFETKCNNSKPK--------------------------------------------------------------------------------------------------------------KSYIATQGCLQ----NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAG----PVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLP----------------------------------------PCTPTPPCAE------------------------------------------------------MREDSARVYENVGLMQQQKSFR----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29349-4", "uniprot_id": "CSW_DROME", "id": "P29349-4", "name": "Tyrosine-protein phosphatase corkscrew", "aln": "MLFNKCLEKLSSSLGNVVNHKLQEKQVYNNNNINNNNNNTLNNNNAYNNQRNFEYERAIQAHYGSKGRRSEERERSGKFKASKGRKAKVTPPTETPEAQEPACKNCMTHDELAQIIKGVAKGADAQRNRDNRLQRRRRPLSAQPSAAASASTSTESLHRLTPSPQASYPATPTSWTATPPQFPAAFGGASCSNSTLSLLATMRVQLHGYTWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDD----------KVTHVMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQL---------VKGGFWEEFESLQ-QDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLVSWRDQ--PARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQTLIARKRAEEQSLQVGREYTNIKYTGEIGNDSQRSPLPPAISSISLVPSKTPLTPTSADLGTGMGLSMGVGMGVGNKHASKQQPPLPVVNCNNNNNGIGNSGCSNGGGSSTTSSSNGSSNGNINALLGGIGLGLGGNMRKSNFYSDSLKQQQQREEQAPAGAGKMQQPAPPLRPRPGILKLLTSPVIFQQNSKTFPKT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::.. : :.* *.: . : :: :.: *.*. * ** .: . .. ::::: : . ::::. : . : **. *::.* *:**::** :**.*: :*: :****** *:******** ..: :***: : : :* *** * *.:*::*::*:*:. : *: *:.: *:** :**:.** *: ** :* .* *******:** *: : ..* ** : **: ****:****:**:** * . : . . ::***** : : .*.: :***:**** **.***.*.:***:*******:* *:*:.**. ***: . :* : * : :*.** : :* .: * :::*:: *******::** **.**:::: :*. : .** *: ************:****:::: : :*:* :**: :******:****:*******:*:* *: ::*:* : . :.. ** **.*. . ::. . ... .:. : .. : : ", "identical_positions": 199, "similar_positions": 187, "identity": "20.58%" }, { "cls_id": "homologset.agr.FB:FBgn0000384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27601-1", "uniprot_id": "GNA13_MOUSE", "id": "P27601-1", "name": "Guanine nucleotide-binding protein subunit alpha-13", "aln": "---------------------------------------------------------------------------MADFLP--SRSVLSVCFP-------GCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGMVETRVFLQYLPAIRALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDS-VTSILFLVSSSEFDQVLMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQ--VVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKRRDQQQRPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q7Y5-1", "uniprot_id": "GNA13_RAT", "id": "Q6Q7Y5-1", "name": "Guanine nucleotide-binding protein subunit alpha-13", "aln": "---------------------------------------------------------------------------MADFLP--SRSVLSVCFP-------GCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQVHGDKLMAFDTRAPMAAQGMVETRVFLQYLPAIRALWDDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDS-VTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQ--VVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKRRDQQQRPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14344-1", "uniprot_id": "GNA13_HUMAN", "id": "Q14344-1", "name": "Guanine nucleotide-binding protein subunit alpha-13", "aln": "---------------------------------------------------------------------------MADFLP--SRSVLSVCFP-------GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDS-VTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQ--IVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27600-1", "uniprot_id": "GNA12_MOUSE", "id": "P27600-1", "name": "Guanine nucleotide-binding protein subunit alpha-12", "aln": "---------------------------------------------------------------------------MSGVVRTLSRCLLPAEAG-ARERRAG-AARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDG-ITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVK--SVSIKKHFPDFKGDPHRLEDVQRYLVQCFDRKRRNRS-KPLFHHFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63210-1", "uniprot_id": "GNA12_RAT", "id": "Q63210-1", "name": "Guanine nucleotide-binding protein subunit alpha-12", "aln": "---------------------------------------------------------------------------MSGVVRTLSRCLLPAEAG-ARERRAG-AARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDG-ITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVK--SVSIKKHFPDFKGDPHRLEDVQRYLVQCFDRKRRNRG-KPLFHHFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03113-1", "uniprot_id": "GNA12_HUMAN", "id": "Q03113-1", "name": "Guanine nucleotide-binding protein subunit alpha-12", "aln": "---------------------------------------------------------------------------MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDG-ITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVK--TVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRS-KPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25157-1", "uniprot_id": "GNAL_DROME", "id": "P25157-1", "name": "Guanine nucleotide-binding protein subunit alpha homolog", "aln": "MSGITLTKLTQERISIPNNNVITNGVENNIDSDTLSGTLTHLMEEHRTRVGAVTGPEAATTSTDGLISNGAERLRLQGSRLQTSRFACFRCCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNS-------LDVPKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNLNALMLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ** * * : :*::** * :*: .:* **:********************** :** . *:: .*:.*:::* :**:***:** *.* . .: .. :: .: :: * * *.: ** * **:.*:.** ***:.:**.****:::::. :*.*:::*** .*:.***: *. . ::::** :*******::*::* .***. :***:*:*****:**** *** **** ** ***:***** * .:******** *** :** ..*: :: .*.*:** : ***.:::: * **. ::*******:*.*:..**. ******: **: :***", "identical_positions": 170, "similar_positions": 108, "identity": "36.64%" }, { "cls_id": "homologset.agr.FB:FBgn0000392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9M0-1", "uniprot_id": "A0A8I6A9M0_RAT", "id": "A0A8I6A9M0-1", "name": "", "aln": "MATGVAGLERCKKIVHQEAMEKRSVDETENGDAFLDLKK------LPTSKSPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDG-VWDPEKWHASLYPASGRSSPVESLKKE----PESDRPSLVRRIADPRERVKEDDLDVVLSPQR-RSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARAFEKDHRLSDKDLRDLRDRDRERDYKDKRFRREFGDSKRVFG-ERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVREGIVECNGGVAEEDEVEVILAQEPSADQEVPRDVILPEQSPGEFDFN-EFFNLDKVPCLASMIEDVLG-----EGSVSASRFSRWFSNP---SRSGSRSSSLGSTPHEELERLAGLEQAVLSPGQNSGNYFAPIPSEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKG------------LKVDQQIKNSTPFMAEHLEETLSAVTSNRQLKKDGDMTAFNKLVNTMKASGTLPT------QPKVSRNLESHLLAPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTASLLSQRAPSPPMSQVFRTQAASADYLHPRIPSPIGFPSGPQQLLGDPFQGMRKPMSPVTAQMSQLELQQAALEGLTLPHDLAVQTTPFYQPGFSKPQVDRTRDG------LRNRQQRMTKSP-----APMHRGNSSSPAP---------------------AASITSMLSPSFTPTSVIRKMYESREKSK-EEIAPGTVVPGDGKEDAQKASEENLLSSNSISNSDQDSSPTANPKLSTLQRSS---------CSTPLSQTNRYTKEQDYRPKAAGRKTPTLASPVPGTPFLRP--THQVPLVPHVPIVRPAHQLH-PGLVQRLIAQGVHPQHLPG------LLQAGVLPPGIDIAPLQGLSGPLLGQPLYPLVSAASHPLLNPRPGTPLHLAVMQQQLQRSVLHPPGSS---SQAAAINVQT-PPNVPS------RSGLPHMHSQLEHRTSQRSSSPVGLAKWFGSDVLQQPLPSMPTKVISVDELEYRQ------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EST3-1", "uniprot_id": "4ET_MOUSE", "id": "Q9EST3-1", "name": "Eukaryotic translation initiation factor 4E transporter", "aln": "-------------------MEK-SVAETENGDAFLELKK------LPTSKSPHRYTKEELLDIKERPYSKQRPSCLSEKYDSDG-VWDPEKWHASLYPASGRSSPVESLKKE----SESDRPSLVRRIADPRERVKEDDLDVVLSPQR-RSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARAFEKDHRLSDKDLRDLRDRDRERDYKDKRFRREFGDSKRVFG-ERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPSADQEVPRDVILPEQSPGEFDFN-EFFNLDKVPCLASMIEDVLG-----EGSVSASRFSRWFSNP---SRSGSRSSSLGSTPHEELERLAGLEQAVLSPGQNSGNYFAPIPSEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKG------------LKVDQQMKNSTPFMAEHLEETLSAASSNRQLKKDGDMTAFNKLVNTMKASGTLPT------QPKVSRNVESHLLAPAEIPGQPVSKNILQELLGQPVQRPASSNLLSGLMGSLEATASLLSQRAPSPPMSQVFRTQAASADYLHPRIPSPIGFPSGPQQLLGDPFQGMRKPMSPVSAQMSQLELQQAALEGLALPHDLAVQTAPFYQPGFSKPQVDRTRDG------LRNRQQRMSKSP-----APMHGGNSSSPAP---------------------AASITSMLSPSFTPTSVIRKMYESREKTK-EEMAPGMVVPGDGKEDTQKTSEENLLSSNPIPNTDQDSS-TTNPKLSTLQRSS---------CSTPLSQTSRYTKEQDYRPKTAGRKTPTLASPVPGTPFLRP--THQVPLVPHVPIVRPAHQLH-PGLVQRLIAQGVHPQHLPS------LLQAGVLPPGIDMAPLQGLSGPLLGQPLYPLVSAASHPLLNPRPGTPLHLAVMQQQLQRSVLHPPGSS---SQAAAISVQT-PQNVPS------RSGMPHMHSQLEHRTSQRSSSPVGLAKWFGSDVLQQPLPSMPTKVISVDELEYRQ------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRA8-1", "uniprot_id": "4ET_HUMAN", "id": "Q9NRA8-1", "name": "Eukaryotic translation initiation factor 4E transporter", "aln": "-------------------MDRRSMGETESGDAFLDLKK------PPASKCPHRYTKEELLDIKELPHSKQRPSCLSEKYDSDG-VWDPEKWHASLYPASGRSSPVESLKKE----LDTDRPSLVRRIVDPRERVKEDDLDVVLSPQR-RSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFRREFGDSKRVFG-ERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPAADQEVPRDAVLPEQSPGDFDFN-EFFNLDKVPCLASMIEDVLG-----EGSVSASRFSRWFSNP---SRSGSRSSSLGSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKG------------LKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPS------QPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDG------FRNRQQRVTKSP-----APVHRGNSSSPAP---------------------AASITSMLSPSFTPTSVIRKMYESKEKSK-EEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSS---------CSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRP--VHQVPLVPHVPMVRPAHQLH-PGLVQRMLAQGVHPQHLPS------LLQTGVLPPGMDLSHLQGISGPILGQPFYPLP-AASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSG---SHAAAVSVQTTPQNVPS------RSGLPHMHSQLEHRPSQRSSSPVGLAKWFGSDVLQQPLPSMPAKVISVDELEYRQ------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMA3-1", "uniprot_id": "CUP_DROME", "id": "Q9VMA3-1", "name": "Protein cup", "aln": "-MQMAEAEQENGAGALKIATNAGATDRPAHQQLPLPVEDQQDEVLTPAEKGKFEYPPPPPPPTPVQAPLATKATALNASQEHDDDEANSEKWEDPCAPPPPPPLPTSAFLATGLGYLKLPAFKLKDALEKAITKLEANKRTLKASPESSRSIKNKNVVALEMLPRRSNPETIGDGS---MLASTSTAVMLQTKKPAVIVEMERRCKIINLLAKQNQILESISGEAIPMHGPSKHLHEDEGLTLQVLSARASTPYTQPSSMLSCTAVSCDLEHDSPRKQVASKEAVPEQQSSQVQQKRPPSTGIHKPGSLRAPKAVRPTTAPVVSSKPVKSYTRSRLMDIRNGMFNALMHRSKESFVMPRIATCDDIELEGRLRRMNIWRTSDGTRFRTRSTTANLNMNNNNNNECMPAFFKNKNKPNLISDESIIQSQPP-QPQTEFQDPAIVNQRRIGSGRLNHSKWGYNDEDYHSYHNGKSQHMEEVNSKNSKNMTVLQFFDNGEISSQPQRRPNTPVMGMSINRSENDTLHSNESSEDLSRANENYVKRVMSGFLVVSKPKSRDVEDRHHRRYRNQNEEPEWFSCGPTSRLDTIELCGFDEDEEKMLKEGNKNHG-LGETERETSKQKMDHKYKWTHAEPMGRSKYMPKHDTNNNHNVENMNNVMATEHQQQKEEKRPGSGRSFQFDKFNQSQQNYESSSYVNHQQPPQTQPQQMQQQSNTNTNNSKFMSFFANEGNSSSSSLNEFFKQAINQGHGNNPEQPKSLGHIGQMPSVDQLEAKWRRNSLNNVGETANKQTDNFQKLIGSLSSAKPQSQAVGYDAISNFIMQQQQYQQQQQKQHLIIQQQQQHTAFLASLQLKAILGRADTQLLLLRLTKGEISKHGLLVQLANPRLTDMDREAITAVLQFTNTQQQQQQHKQQLDMLSSTVIASQLQNLHNLAIVQQTLAARQQPQHNPQTQAPHQLSQEDLQAHANVIMRNAVMKRKIEEQTSKLINGGAKHQAQQQYLNRGQQRQARPDANSNALLHALISGGGNNHASGYPMNGQPQKHHSNLRFGDNQNFQSFESNQPHFATQYKQQYQQSQQQHPHQQPQQLNSLHQNNAGAVNSFNKAQMQAQSAISMLPNSGDEFH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. : * ::. *:.* ..*. . :.:.*. . : *. :.***. . *.. . *..:: . .* : .. ::: :. : **: **: . *: : .***.. *.. :*.. . . :. : . * :. * .::: : . . .* **::. * : : . . :: .: * * .::.. .:: .:: . .: :* : . *: : ..:.. * .*:: *. . : . . :*:. :** . *:: :. * . *:. * :. *: * ::.*. . ::: * :..: : .*. *.: : :.:.:.: :::: ::. * * . ::: .* *.* :***:: . :. : * : .**.*. ::.: . . ..: .:* . : * : .*.. .:.. : : *. ..: * :. *..: ** * :. : . * * * .:: . . .. . :.*: : .. . ::::. .* :: * :.: *:: : : :. . : * . ** : * : . :. : *. : :.* .:: *:...* *:..: ..: . *. ::*: * ..:* :. * * . .: : *: .::: . : . ::.:: :. :*.:: : . :*: . .: : * . .*:: * . .. * : :*: ::. . :. ::** .:**: :* :*** * * * .: . . : :. : *. : .*.* : . : : ..::**. *. .:*:. :: * : * ...: :.*: * .:* ... : . : ** . :. :*:.:: * ", "identical_positions": 126, "similar_positions": 391, "identity": "11.22%" }, { "cls_id": "homologset.agr.FB:FBgn0000394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9T2-1", "uniprot_id": "D4A9T2_RAT", "id": "D4A9T2-1", "name": "", "aln": "MNSHHV--VLTLASLMFLMCLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELTHHENLVSFLETVNQPHHQN-VSVPSNNVHAPFPSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECVGPECIDYGSKTVKCMNCMF-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP52-1", "uniprot_id": "TWSG1_MOUSE", "id": "Q9EP52-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKSHYI--VLALASLTFLLCLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQLHHQN-VSVPSNNVHAPFPSDKERMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZX9-1", "uniprot_id": "TWSG1_HUMAN", "id": "Q9GZX9-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKLHYVA-VLTLAILMFLTWLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQN-VSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGH0-1", "uniprot_id": "TWS1A_DANRE", "id": "Q9DGH0-1", "name": "Twisted gastrulation protein homolog 1-A", "aln": "MRPALFLCPVLISVLFLLSSLSLISGCNKALCASDVSKCLLQGLCQCRPQEGNCSCCKECMLCLSSLWEECCDCVGMCNPRSYNDSPATSKSTVEELYRPIPSLFRALTEGDAPINMMVVSFPVAEELSHHENLVSFLETLDSQSQN--ISLP-----TSSAQD-DALCTVVYFDDCVSIRQCKQYCESMGGSKYRWFHNACCECIGPECLDYGSKTVKCMNCLI-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98SR9-1", "uniprot_id": "TWS1B_DANRE", "id": "Q98SR9-1", "name": "Twisted gastrulation protein homolog 1-B", "aln": "MGSSSSSSVVLL--LLLLSSLSIALACNKALCASDVSKCLIQELCQCRPADGNCSCCKECMLCLGSLWEECCDCVGMCNPRSMSESPATGRSTVEDLFQPIPSLFRALTEGDAPTHTLVLTLPLAEELQYQHNLHNYLETLHNTQHNNTTSVPENSIHSSYHTQ-DKQCTVVYFDECVSIRQCKQYCESMGGSKYRWFHNACCQCIGPECVDYGSKSVRCLNCLY-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W494-1", "uniprot_id": "Q9W494_DROME", "id": "Q9W494-1", "name": "", "aln": "MEIWRSLTVGTIVLLAIVCFYGTVESCNEVVCASIVSKCMLTQSCKCELK--NCSCCKECLKCLGKNYEECCSCVELCPKPNDTRNSLSKKSHVEDFDG-VPELFNAVATPDEGDSFGYNWNVFTFQVDFDKYLKGPKLEKDGHYFLRTNDKNLDEAIQERDNIVTVNCTVIYLDQCVSWNKCRTSCQTTGASSTRWFHDGCCECVGSTCINYGVNESRCRKCPESKGELGDELDDPMEEEMQDFGESMGPFDGPVNNNY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * :: .**:.:*** ****:: *:*. **.*****: **. ::***.** :* . . .. : :* **:: :*.**.*:: * .: :: ... * . . . ***:*:*:*:* .:*: *:: *.*. ****:.**:*:*. *::** : :* :* ", "identical_positions": 61, "similar_positions": 62, "identity": "23.46%" }, { "cls_id": "homologset.agr.FB:FBgn0000395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M661-1", "uniprot_id": "F1M661_RAT", "id": "F1M661-1", "name": "BMP-binding endothelial regulator protein", "aln": "-------MLWFSGVRALAERPCRRSPG---------ITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP-FITDNPCIMCVCSNKEVTCKREKCPVLSRDCALAIKQRGACCERCKGCTHEGRTYNSSFKWQSPAEPCALRQCQEGVVTESEVRCVVHCKN---PAEHPGACCPTCPGCVFEGVQYREGEEFQP-EANKCIKCSCVGGRTQCVREVCPILSCPQHLSHTPSGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGASFVYDNCTVCTCKDSTMVCKKKCSHPGVCNTDEDACCEECLLRVPPEDVKVCKFGSKIFRDGEMWSSVNCSICACVKGKTECRKKQCVPVSSCPQGKILNRKG-CCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESTVSLQQHLTVRWNGSRIALP------CHTPHFHIDLDGYLLKVTTRAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDG--NFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYTTFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEPQQSCAATQCKHGAVYDTCG-------------------------------PGCVKTCDNWNEIGPCNKPCIAGCHCPANLVLHKGRCIKPVLCPQR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ69-1", "uniprot_id": "BMPER_MOUSE", "id": "Q8CJ69-1", "name": "BMP-binding endothelial regulator protein", "aln": "-------MLWFFSVRALAERPCRRSPG---------ITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP-FITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCERCKGCTHEGRTYNSSFKWQTPAEPCVLRQCQEGVVTESEVRCVVHCKN---PAEHQGACCPTCPGCVFEGVQYREGEEFQP-EGNKCITCSCVGGRTQCVREVCPILSCPQHLSHTPSGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGASFVYDNCTVCTCKDSTMVCKKKCSHPGVCNSDEDACCEDCLLRVPPEDIKVCKFGSKIFRDGEMWSSVNCSICACVKGKTECRKKQCVPVSSCPQGKILNRKG-CCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELMLGESTVSLQQHLTVRWNGSRIALP------CHTPHFHIDLDGYLLKVTTRAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDG--NFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYTTFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEPQQSCAATQCKHGAVYDTCG-------------------------------PGCVKTCDNWNEIGPCNKPCIAGCHCPANLVLHKGRCIKPVLCPQR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8U9-1", "uniprot_id": "BMPER_HUMAN", "id": "Q8N8U9-1", "name": "BMP-binding endothelial regulator protein", "aln": "-------MLWFSGVGALAERYCRRSPG---------ITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP-FITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKN---PLEHLGMCCPTCPGCVFEGVQYQEGEEFQP-EGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKG-CCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALP------CRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDG--NFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCG-------------------------------PGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQR-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2H2-1", "uniprot_id": "Q9W2H2_DROME", "id": "Q9W2H2-1", "name": "", "aln": "MCCQSSGQWKFPAQQPRKSLASRRRHTGFRPSTQLLILIAVLLALLQGRTVDAGAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNGFVNCR-DTCPPVN-DCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVP-GKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMG--KTFHIRLTNEGRGTRRASWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTCDKRKSNFYCH---PLSVPALFGECNERLNPENYKAACRMDVCECPSGD-CHCDSFAAYAHECRRLGVQLPDWRSATNCPAGWRRNATLSSFKGNQFYGDPSFSRMKGRRQKNHQLRLQLQQEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTPPPLH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . .** * .*** * . . : *.. *:* .*.**** :*: .*: * * * *.*: :.** :. ** : *..*:**.:****:..* :*:*. :*: * :** :* ****: :* :*.* : * ***** ** ::* **.*.:. .:* *.* * : * ::.**:*.** . ..:***:* ::..: :* *.***...** : :.*: *.** *** :.* **:: . * : * . .* . *.:.. ::::.* *. * * * * .* : :* .:.. .: :: : * ** *.*..*.********:.****: *.***:*:*:*:.** . ..*:: :.*:.* ** **:*:* * * : *.* *:: *: **:*::** : :. :* : : :. ** :.*:* .*::* ...::* :*******:** .**** * ** : . :* .**:**:* . : *.* :. .. .. * :: .* . * *:. :: .: :* *:**** . *:*:** **:: *:* *::: .*.. .*.* ::.:: . * . : .. :: * *: * : : *:* :* * .. ", "identical_positions": 214, "similar_positions": 224, "identity": "28.16%" }, { "cls_id": "homologset.agr.FB:FBgn0000404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY13-1", "uniprot_id": "CCNA1_RAT", "id": "Q6AY13-1", "name": "Cyclin-A1", "aln": "--------------------------------------------MRRHSSKSGVALPPVGQGPDACQMLTRAQLGQDPPQRTVLGVLTENEQYRRACGQEIATIRCFSGSENVFPAAGKKVLPDNGVSEPAKH-GFDIYMDDPE------------QGDRDSCPGREGIVFEDVYEVD-TSMLKSDLHFLLDFNTVSPMLVDSTAHAQSEEATDFGS-------------DVINVTEYAEEIHRYLREAEVRHRPKAHYMRKQPDITEGMRAILVDWLVEVGEEYKLRTETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAILLASKYEEIYPPDVDEFVYITDDTYTKRQLLRMEHLLLKVLAFDLTVPTTNQFLLQYLRRQG-VCIRTENLAKYVAELSLLEADPFLKYLPSLVAAAAYCLANYIVNRHFWPETLAAFTGYSLNEIVPCLSELHKACLSIPHRPQQAIREKYKASKYLHVSLMEPPVVLPLQ----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61456-1", "uniprot_id": "CCNA1_MOUSE", "id": "Q61456-1", "name": "Cyclin-A1", "aln": "--------------------------------------------MHRQSSKSGVALPPVGQGPDACQMLSRAQLGQDPPQRTVLGVLTENEQYRRTCGQEITAIRCFSGSENVFPAAGKKVLSDHGVNEPAKR-GFDIYMDDPE------------QGDRDTCSGKEGIIFEDVYEVD-TSMLKSDLHFLLDFNTVSPMLVDPTTHAQSEEATDFGS-------------DVINVTEYAEEIHRYLREAEVRHRPKAHYMRKQPDITEGMRAILVDWLVEVGEEYKLRTETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAILLASKYEEIYPPDVDEFVYITDDTYTKRQLLRMEHLLLKVLAFDLTVPTTNQFLLQYLRRQG-VCIRTENLAKYVAELSLLEADPFLKYLPSLVAAAAYCLANYIVNRHFWPETLAAFTGYSLNEIVPCLSELHKACLSIPHRPQQAIREKYKASKYLHVSLMEPPVVLPLQ----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78396-1", "uniprot_id": "CCNA1_HUMAN", "id": "P78396-1", "name": "Cyclin-A1", "aln": "METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQ-GFDIYMDELE------------QGDRDSCSVREGMAFEDVYEVD-TGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGT-------------DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQG-VCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGH4-1", "uniprot_id": "F1QGH4_DANRE", "id": "F1QGH4-1", "name": "", "aln": "-----------------------------------------------MSSRS---FAPLSSRQENILGRAEGLRQLKPGQRIVLGVLTENEQHNRIFGQVASKY-------------------ETTLQEVSKR-DVSTFRASIG------------DSVIETATVQS--VKSTSFLLP-SELLVLD-DAVQDIGSGS--FMDSSMHSLADEEAASSE-------------DVLCVSEYAEDIHRYLRECEVKYRPKPGYMRKQPDITNCMRVILVDWLVEVGEEYKLCSETLYLAVNYLDRFLSCMSVLRGKLQLVGTAAILLAAKYEEVYPPEVDEFVYITDDTYTKKQLLRMEQHLLRVLAFDMTAPTIHQFLMQYSLEEH-VCARTLNLALYLSELSLLEVDPFVQYLPSKTAAAAYCLANYTLNGALWPENLYAFTGYSLAVIGPCLKELHKLHLGAGSRPQQAIQEKYKSSKYHGVSQLEPVETLPLP----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JVY9-1", "uniprot_id": "A0A0G2JVY9_RAT", "id": "A0A0G2JVY9-1", "name": "Cyclin-A2", "aln": "----------------------------------MPGNSRQ------AGSALLS-----QQEDQENVNPEKVAPAQQPR---AQAVLKAGKVRGPAPQQRLKTRR--VAPLKDLPINDEHVPTVPSWKAVSKQPAFTIHVDEAE-ETQKR------PAEQKETQCEDALAFSAAVSLPGARKPLVPLDYPMDGSFESPHAMDISIVLEDEKPVNVN-----------------EVPDYHEDIHTYLREMEVKCKPKVSYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQSWPESLVQKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETLNV-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51943-1", "uniprot_id": "CCNA2_MOUSE", "id": "P51943-1", "name": "Cyclin-A2", "aln": "----------------------------------MPGTSRHS--GRDAGSALLSL----HQEDQENVNPEKLAPAQQPR---AQAVLKAGNVRGPAPQQKLKTRR--VAPLKDLPINDEHVTAGPSWKAVSKQPAFTIHVDEAE-ETQKR------PAELKETECEDALAFNAAVSLPGARKPLTPLDYPMDGSFESPHAMDMSIVLED-KPVNVN-----------------EVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQSWPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETLSV-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20248-1", "uniprot_id": "CCNA2_HUMAN", "id": "P20248-1", "name": "Cyclin-A2", "aln": "----------------------------------MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRR--VAPLKDLPVNDEHVTVPP-WKANSKQPAFTIHVDEAEKEAQKK------PAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIILEDEKPVSVN-----------------EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14785-1", "uniprot_id": "CCNA_DROME", "id": "P14785-1", "name": "G2/mitotic-specific cyclin-A", "aln": "-----------------------------------MASFQIHQDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCD-MPEKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKVAMMESVEMSKDDFDQLCEAYNCKQKEDEHQQPDINTKSNVNLFYKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*. . : * . . . : . . . . :: : . * :* :* *:** * : :** **::* **:. ** **:******.***** ***:*:* ::***** *:*:*.*********: :*:*:**:***:* ***::***:*:* *:*:**: :*::*:**: .** *: * : :: ::.****:: :.:::**** :.*: ** : : *. * * *.* : . : .* : *:::***: ..* *: ::. ", "identical_positions": 104, "similar_positions": 91, "identity": "19.73%" }, { "cls_id": "homologset.agr.FB:FBgn0000405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24870-1", "uniprot_id": "CG23_YEAST", "id": "P24870-1", "name": "G2/mitotic-specific cyclin-3", "aln": "---------------------------MHHNSQSLSSGHIRSPEDENVAPIGNLKHR--TGSLSHISSAHPRVALSDVTNIVAT--------------------------NSSNNSISKPKVAPIKERLDSAAIIEEERLDANS-----------------VAQRKE-------------------------------ADHNDLLTDREQEEPVED-------DGES----EEDEE--EDQEPLLLQHYASDTLVWEHAFRTYYRTTLDPNDDDVYDVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPE---LRWSFRSTLIDWIVQVHEKFQLLPETLYLCINIIDRYLCKEVVPVNK-FQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHRLVSAQPSWLAAGAYFLSKIILG----------QNQWSLAHVYYSNYTQE----QILPLATIILENCRYASKRHNAIWRKYSSRRYLHSSQIVAKWIALAEHRVERSN----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24871-1", "uniprot_id": "CG24_YEAST", "id": "P24871-1", "name": "G2/mitotic-specific cyclin-4", "aln": "---------------------MMLEGYTVQPPQSTLIGDIEIQDENANQEVKNVLYQGVQKGIKRLEKRQRRVALGDVTSQKANK-----------------------IHNAIHNKFHQTKNNFEIENIRSSALVKEQQRDVRHEDSDYFLIDSSEGSSTDDEQVNE-------------------------------DAIDDLLSRRVNDQQIQADEVYEDFDGEMQDVIEEDVD--SQIEPLSPINNDEIQTELDRAFEKYFRSVPNPLDDDTHDVVMVVEYASDIFYYLRELEVKYRPNPYYMQNQVE---LTWPFRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKTVTLNR-FQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKLVAAAPSWLAAGAYFLSRTILG----------SNDWSLKHVFYSGYTSS----QIIPLASLILENCKNASRRHHSIWKKYFDQKHYRCSQIVEEWIVSTEA----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24868-1", "uniprot_id": "CG21_YEAST", "id": "P24868-1", "name": "G2/mitotic-specific cyclin-1", "aln": "----------------MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSK-------------------------------LNNFFPLKDDVSR---ADDFTSSFNDS-RQGVKQEVLNNKEN----IPEYGYSEQEK------------QQCSNDDSFHTN--------STALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKN----IKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNR-LQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLG----------KGTWDGNLIHYSGGYTK----AKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24869-1", "uniprot_id": "CG22_YEAST", "id": "P24869-1", "name": "G2/mitotic-specific cyclin-2", "aln": "----------------MSN--PIENTENSQNTSSSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSR-------------------------------IPQFT--RESVSRSTAAQEEKRTLKENGIQLPKNNLLDDKENQDPSSQQFGALTSIKEGRAELPANISLQESSSAKEIIQHDPLKGVGSSTEVVHNSVENEKLHPARSQLQVRNTESETDSGKKRPISTIVEQELPKKFKVCD----ENGKEEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLYQHRN----IHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDK-LQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLG----------KGKWDGNLIHYSGGYTK----EELAPVCHMIMDYLVSPIVHDEFHRKYQSRRFMKASIISVQWALKVRKNGYDIMTLHE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32943-1", "uniprot_id": "CGS6_YEAST", "id": "P32943-1", "name": "S-phase entry cyclin-6", "aln": "------------------------------------MNCIPSPISER------------KIQINNEDCIGKENAFHTIPR-----------------------------ESSINLTPHSTNE--------KKVLSEVN--------------------------------------------------------------SNKIDSLQLPRGKLQRDSTHLEKTRKRQLSNDST----DPIEPKTVKK-IKCH------------QWKNLDSIEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNK-LQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNEN-------SK--WDETFIHYSGGIDIESDPAFKDFISELVEDIAVPDTNLDSLRLKYKKPKHGMVYFKVFDWCKQKR-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P30283-1", "uniprot_id": "CGS5_YEAST", "id": "P30283-1", "name": "S-phase entry cyclin-5", "aln": "------------------------MGENHDHEQSIKRNSMIYNENERQLCNSNLKILQNKRALSKNDSSSKQQVQDSKPRRALT-------------------------DVPVNNNPLSQNKRIVAGSKAAKVRREEN--------------------------------------------------------------IRPIVSAVQKR-QIYNDRTAAEQEEEEEEEGEDD----DAASIVNKKRRIDAEG------VSEIVGWQDLDYVEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNK-LQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCHQFIHLPPSTVSAMAMYIARRMTNRN-------KNELWNGTLQHYSGGIDPIHDEAFQSLCIDLVKDIASSKTHLDSLILKYKKPRYGSVYFQTFKWCTSEMHSNFQNLFNLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24860-1", "uniprot_id": "CCNB1_MOUSE", "id": "P24860-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------MALRVTRNTKINAENKAKVSMAGAKRVPVTVTAASKPGLRPRTALGDIG----------------------------------NKVSEELQARVPLKREAKTLGTGKGTVK----------------------ALPKPVEK---------------------------VPVCEPEVELA---EPEPEPELEHVREEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILA-VSDVDADDGADPNLCSEYVKDIYAYLRQLE-EEQSVR--PKYLQG-REVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNSCVPKKM-LQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSYSED-SLLPVMQHLAKNVVMVNCGLTKHMTVKNKYAASKHAKISTLAQLNCTLVQNLSKAVTKA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30277-1", "uniprot_id": "CCNB1_RAT", "id": "P30277-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------MALRVTRNTKINTENKAKVSMAGAKRVPVAV-AASKPLLRSRTALGDIG----------------------------------NKVSE--QSRIPLKKETKKLGSGTVTVK----------------------ALPKPVDK---------------------------VPVCEPEVELD---EPEPEP----VMEVKHSPEPILVDTPSPSPMETSGCAPAEEYLCQAFSDVILA-VSDVDADDGGDPNLCSEYVKDIYAYLRQLE-EEQSVR--PKYLLG-REVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDSCVPKKM-LQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSHTEE-SLLPVMQHLAKNIVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAVTKA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14635-1", "uniprot_id": "CCNB1_HUMAN", "id": "P14635-1", "name": "G2/mitotic-specific cyclin-B1", "aln": "------------------------------MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIG----------------------------------NKVSEQLQAKMPMKKEAKPSATGKVIDK----------------------KLPKPLEK---------------------------VPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILA-VNDVDAEDGADPNLCSEYVKDIYAYLRQLE-EEQAVR--PKYLLG-REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKM-LQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILD----------NGEWTPTLQHYLSYTEE-SLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M857-1", "uniprot_id": "Q5M857_RAT", "id": "Q5M857-1", "name": "", "aln": "------------------------------MALLRRPTVSSDLKNIDTGVNPKAK---------SHVTVR-RAVLEEIG----------------------------------NKVRAR-PAQVAKKPQNTKVPVQPTKAI----------------------NASK---------------------------------------------QPKPTASVKPVQMETLAPK-----DPLPAPEDVS---MKEESLCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLEQALQSIN--PHFLDG-RDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTGYMES-EILEVMQHMAKNVVKVNENLTKFIAVKNKYASSRLLKISTIPQLNSRTIKDLASPLMGRP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A3R0-1", "uniprot_id": "A0A8I6A3R0_RAT", "id": "A0A8I6A3R0-1", "name": "", "aln": "------------------------------MALLRRPTVSSDLKNIDTGVNPKAK---------SHVTVR-RAVLEEIG----------------------------------NKVRAR-PAQVAKKPQNTKVPVQPTKAI----------------------NASK---------------------------------------------QPKPTASVKPVQMETLAPK-----DPLPAPEDVS---MKEESLCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLE-ALQSIN--PHFLDG-RDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTGYMES-EILEVMQHMAKNVVKVNENLTKFIVP------------VYICMLYTEEM------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30276-1", "uniprot_id": "CCNB2_MOUSE", "id": "P30276-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "------------------------------MALLRRPTVSSDLKNIDTEVIPKAK---------SHVTIR-RAVLEEIG----------------------------------NKVRNR-TTQVAKKPQNTKVPALPTKVT----------------------NVNK---------------------------------------------QPKPTASVKPVQMEALAPK-----DRPPAPEDVS---MKEESLCQAFSDALLCKIEDIDNEDRENPQLCSDYVKDIYQYLRQLE-VLQSIN--PHFLDG-RDINGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQLVCRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLG----------QGKWNLKQQYYTGYMES-EVLEVMQHMAKNVVKVNDNRTKFIAVKNKYASSRLLKISTIPQLNSKIIKDLASPLLGSP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95067-1", "uniprot_id": "CCNB2_HUMAN", "id": "O95067-1", "name": "G2/mitotic-specific cyclin-B2", "aln": "------------------------------MALLRRPTVSSDLENIDTGVNSKVK---------SHVTIR-RTVLEEIG----------------------------------NRVTTR-AAQVAKKAQNTKVPVQPTKTT----------------------NVNK---------------------------------------------QLKPTASVKPVQMEKLAPK-----GPSPTPEDVS---MKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLE-VLQSIN--PHFLDG-RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKK-LQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG----------QGKWNLKQQYYTGYTEN-EVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20439-1", "uniprot_id": "CCNB_DROME", "id": "P20439-1", "name": "G2/mitotic-specific cyclin-B", "aln": "MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMG---------------------------VSGIRREPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVE-LEQPIH--KDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAA-HLRPITRLIAK--LARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQRK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : : : .*: .: . * . * :::*: ::: :* **: : : ::**:: :**: :.:::* *:**: * : . . :. : : * :: : :. . *: *:** ** :.:.*:::* : : ** :: : :: : . . * .* ", "identical_positions": 29, "similar_positions": 70, "identity": "5.13%" }, { "cls_id": "homologset.agr.FB:FBgn0000406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0R9-1", "uniprot_id": "FADS2_MOUSE", "id": "Q9Z0R9-1", "name": "Acyl-CoA 6-desaturase", "aln": "-------------------------------MGKGGNQGEGSTERQAPMP-------------TFRWEEIQKHNLR-TDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESLAWFILSYFGTGWIPTLVTAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHVVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLH--VFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMISRRDWVDLAWAISYYMRFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHLVMEIDLD--HYRDWFSSQLAATCNVEQSFFNDWFSG-HLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALIDIVSSLKKSGELWLDAYLHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z122-1", "uniprot_id": "FADS2_RAT", "id": "Q9Z122-1", "name": "Acyl-CoA 6-desaturase", "aln": "-------------------------------MGKGGNQGEGSTELQAPMP-------------TFRWEEIQKHNLR-TDRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESIAWFILSYFGNGWIPTVITAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLH--VFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIRRRDWVDLAWAISYYARFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHIVMEIDLD--HYRDWFSSQLAATCNVEQSFFNDWFSG-HLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIVSSLKKSGELWLDAYLHK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920L1-1", "uniprot_id": "FADS1_MOUSE", "id": "Q920L1-1", "name": "Acyl-CoA (8-3)-desaturase", "aln": "-------------------------------MAPDPVPTPGPASAQLRQTR------------YFTWEEVAQRSGREKERWLVIDRKVYNISDFSRRHPGGSRVISHYAGQDATDPFVAFHINKGLVRKYMNSLLIGELAPEQPSFEPTKNKALTDEFRELRATVERMGLMKANHLFFLVYLLHILLLDVAAWLTLWIFGTSLVPFILCAVLLSTVQAQAGWLQHDFGHLSVFGTSTWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDIN-MHPLFFALGKVLPVELGREKKKHMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVVQRKKWVDLAWMLSFYARIFFTYMPLLGLKGFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHD--RNVDWVSTQLQATCNVHQSAFNNWFSG-HLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKYGIKYESKPLLTAFADIVYSLKESGQLWLDAYLHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCK6-1", "uniprot_id": "D3ZCK6_RAT", "id": "D3ZCK6-1", "name": "", "aln": "MKLEEKLEHNESLVGKSRPCLNDTHQANGKHIANGNLRANGNVEVYEKQEANGKGDRLRKCLNLYTWQEIQKHNQE-TDQWLVIDRKVYNVTDWAGKHPGGHRVLNHYAGEDATDAFRAMHLDPSIVQLYLKPLLIGELSPEEPSQEKNKNPQLVEDFRELRKTLEDMNMFSANLWFFFLHLAQILILEVLAWLILRHFSSGWIVTILISFLLTVSQAQSSFLQHDIGHLSMFKKSKWNHLMHKFVMCHLKGLSADWWNYRHFQHHVKPNIYPKDPDIDVGP--LFLLGDTQPIKYGKKKIKYIDYEKQHLYFYMVALPLLMPVYFNLQSMQVMYLRKYWTDIVWVSSFYIRYFITFGPFYGIFGTVLLIYLVKFIESPWIAYVTQMSHIPMKMSRE--ENLDWLSTQIVATCNIEQSFFNDWFTG-HLNFQIEHHLFPTMPRHNYHKVAPLVKSLCTKHGLQYINKPILKAFGDIVRSLKKSAALWMDAYYE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VAX3-1", "uniprot_id": "FS2P1_MOUSE", "id": "Q0VAX3-1", "name": "Fatty acid desaturase 2-like protein FADS2B", "aln": "MKLEEKLEHNESLVGKSRPCLHDTHQANGKPIANGNPTANGKVEVYEKQEANGKGNRLGKCLNLYTWQEIQRHSQE-ADQWLVIDRKVYNVTDWAGKHPGGRRVLNHYAGQDATDAFRAMHLDLGMVKLYLKPLLIGELSPEEPSQEKNKNAQLVEDFRELRKTLEAMNMFSANLRFFFLHLAQILILEISAWLILHHFGSSWLVTILISFLLTVSQAQCSFLQHDLGHLSMFKKSKWNHLMHKFVMCHLKGLSADWWNYRHFQHHVKPNIYPKDPDIDVGP--LFLVGDTQPIKYGKKKIKYIDYEKQHLYFYMVALPFLMPVYFNLQSMQVMYLRKYWMDIAWVSSFYIRYFITFGPFYGIFGTVLLIYLVKFIESPWIAYVTQMSHIPMKMSSE--ENHDWLSTQVVATCNIEQSFFNDWFTG-HLNFQIEHHLFPTMPRHNYHKVAPLVKSLCAKHGLQYINKPILKAFGDIVRSLKKSASLWMNAYYE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19967-1", "uniprot_id": "CYB5R_DROME", "id": "P19967-1", "name": "Cytochrome b5-related protein", "aln": "-------------------------------MVIEEWKKSGIATKFPTYRN-------SALITTHSWQKGKRQDDG-AEGLWRINDGIYDFTSFIDKHPGGPFWIRETKGTDITEAFEAHHLTTAPEKMIAKYKVRDAAEPRIYTLTLEEGGFYKTLKERVREQLKTIDKRPK-------KKSDLIHLGLVVSLYLLGIASAKYNSLLALVLASVALCWTVIVSHNYFHR------RDNWQMYAFNLGMMN--FAAWRVSHALSHHIYPNSY-FDLELSMFEP---LLCWVPNPHIKSKLMRYVSWVTEPVAYALAFFIQMGTRIFYSLRHTNILYWHDLLPLTIPIAIYLGTGGSLGIWICVRQWLAMTSIASFSFCLIGLNAAHHDPEIYHEGDANREDRDWGLFQVDTIIDRGDLKWSQFLVLTHFGDHVLHHLFPTLDHGLLPALYPVLYQTLDEFKGHLRECNHIEHMIGQHKQLLRIEPNPRAPGAGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . . *:: ::. : *: :*:.:.: :**** : . * * *:.* * *: : : . *. : :. . :: : :. .:: : . : * :... :: .: :. . :.*: * * :: * : :: * * :.** ** : * ::. : . : ::: : : : : : . * : : :. : * : : : : : * . .:: . . . . ** *: : : : :.::: *:. :: ******: : : *:: . :. . . : : . .* . . ", "identical_positions": 42, "similar_positions": 125, "identity": "8.5%" }, { "cls_id": "homologset.agr.FB:FBgn0000411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LE60-1", "uniprot_id": "A0ABK0LE60_RAT", "id": "A0ABK0LE60-1", "name": "", "aln": "---------------------------------------------------------------------------MYN-MMETELKPPGPQQASGGGGGG-------GNATAAATGGNQK-------------------NSPDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LMKKDKYTLPGGLLAPG---GNSMASGVGVGAGLG-AGVNQRMDS-----------YAHMNGWSNGSYS------------MMQEQLGYPQHPGLNAHG----------------AAQMQPMHRYDVSALQYNSMTSS--QTYMN------GSPTYS---------------MSYSQQGT---------PGMALGSMGSVVKSEASSSPPVVTSSSHSRA-PCQAGDLRDMISMYLP------GAEVPEPAAPSRLH-MAQHYQSG------PVPGTAINGTLPLSHM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48432-1", "uniprot_id": "SOX2_MOUSE", "id": "P48432-1", "name": "Transcription factor SOX-2", "aln": "---------------------------------------------------------------------------MYN-MMETELKPPGPQQASGGGGGG-------GNATAAATGGNQK-------------------NSPDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LMKKDKYTLPGGLLAPG---GNSMASGVGVGAGLG-GGLNQRMDS-----------YAHMNGWSNGSYS------------MMQEQLGYPQHPGLNAHG----------------AAQMQPMHRYVVSALQYNSMTSS--QTYMN------GSPTYS---------------MSYSQQGT---------PGMALGSMGSVVKSEASSSPPVVTSSSHSRA-PCQAGDLRDMISMYLP------GAEVPEPAAPSRLH-MAQHYQSG------PVPGTAKYGTLPLSHM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48431-1", "uniprot_id": "SOX2_HUMAN", "id": "P48431-1", "name": "Transcription factor SOX-2", "aln": "---------------------------------------------------------------------------MYN-MMETELKPPGPQQTSGGGG---------GNSTAAAAGGNQK-------------------NSPDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LMKKDKYTLPGGLLAPG---GNSMASGVGVGAGLG-AGVNQRMDS-----------YAHMNGWSNGSYS------------MMQDQLGYPQHPGLNAHG----------------AAQMQPMHRYDVSALQYNSMTSS--QTYMN------GSPTYS---------------MSYSQQGT---------PGMALGSMGSVVKSEASSSPPVVTSSSHSRA-PCQAGDLRDMISMYLP------GAEVPEPAAPSRLH-MSQHYQSG------PVPGTAINGTLPLSHM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0E1-1", "uniprot_id": "SOX2_DANRE", "id": "Q6P0E1-1", "name": "Transcription factor Sox-2", "aln": "---------------------------------------------------------------------------MYN-MMETELKPPAPQPNTGGTG------------NTNSSGNNQK-------------------NSPDRIKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LMKKDKYTLPGGLLAPG---GNGMGAGVGVGAGLG-AGVNQRMDS-----------YAHMNGWTNGGYG------------MMQEQLGYPQHPSLNAHN----------------TAQMQPMHRYDMSALQYNSMTNS--QTYMN------GSPTYS---------------MSYSQQST---------PGMTLGSMGSVVKSESSSSPPVVTSSSHSRAGQCQTGDLRDMISMYLP------GAEVQDQSAQSRLH-MSQHYQSA------PVPGTTINGTIPLSHM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZM42-1", "uniprot_id": "A0A8I5ZM42_RAT", "id": "A0A8I5ZM42-1", "name": "", "aln": "MRPARENASGERSPRVPADFARSPSASLPFPPELPARRPPSATPTESPGLFTVAAPAPGAPSPPATLAHLLPAPAMYS-LLETELKNPVGPPTPAAATGGPPAPGAAGKSSANPAGGANAGSGGSGGANGGGGGGGGG-SDQDRVKRPMNAFMVWSRGQRRKMALENPKM-----HNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKT---LLKKDKYSLPGGLLPPG-AAAAAAAAAAAAAASSP-VGVGQRLDT-----------YTHVNGWANGAYS------------LVQEQLGYAQPPSMSSPP---------------PPPALPQMHRYDMAGLQYSPMMPPGAQSYMNAAAAAAAASGYGGMAPSAAAAAA----AAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRAC----LGDLRDMISMYLPPG--GDAADAASPLPGGRLHGVHQHYQG---------AGTAVNGTVPLTHI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53784-1", "uniprot_id": "SOX3_MOUSE", "id": "P53784-1", "name": "Transcription factor SOX-3", "aln": "---------------------------------------------------------------------------MYS-LLETELKNPVGPPTPAAGTGVPAAPGAAGKSGANPAGGANAGNGGSGGANGGGGGGGGGGSDQDRVKRPMNAFMVWSRGQRRKMALENPKM-----HNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKT---LLKKDKYSLPGGLLPPG-AAAAAAAAAAAAAASSP-VGVGQRLDT-----------YTHVNGWANGAYS------------LVQEQLGYAQPPSMSSPP---------------PPPALPQMHRYDMAGLQYSPMMPPGAQSYMNAAAAAAAASGYGGMAPSAAAAAA----AAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRAC----LGDLRDMISMYLPPG--GDAADAASPLPGGRLHGVHQHYQG---------AGTAVNGTVPLTHI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41225-1", "uniprot_id": "SOX3_HUMAN", "id": "P41225-1", "name": "Transcription factor SOX-3", "aln": "MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYS-LLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGG-----TDQDRVKRPMNAFMVWSRGQRRKMALENPKM-----HNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKT---LLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSP-VGVGQRLDT-----------YTHVNGWANGAYS------------LVQEQLGYAQPPSMSSPP---------------PPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAA----AAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRAC----LGDLRDMISMYLPPG--GDAADAASPLPGGRLHGVHQHYQG---------AGTAVNGTVPLTHI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6EJB7-1", "uniprot_id": "SOX3_DANRE", "id": "Q6EJB7-1", "name": "Transcription factor Sox-3", "aln": "---------------------------------------------------------------------------MYN-MMETEIKSPIPQSNTGSVTG--------GKNNS-----AN---------------------DQDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKTKT---LLKKDKYSLPGGLLAPG-----------ANAVNNA-VSVGQRMD------------YTHMNGWTNSAYS------------LMQDQLAYPQHPSMNSP-------------------QIQQMHRYDMAGLQY-PMMST-AQTYMN------AASTYSSMSP------------AYTQQTS---------SAMGLGSMASVCKTEPSSPPPAITSHSQRAC----LGDLRDMISMYLPPG--GDSADHSS-LQTSRLHSVHPHYQS---------AGTGVNGTLPLTHI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DGL6-1", "uniprot_id": "SOX1A_DANRE", "id": "Q6DGL6-1", "name": "Transcription factor Sox-1a", "aln": "---------------------------------------------------------------------------MYSMMMETDLHSPG-PQTNTNP----------GQTGPNSG----------------------SKANQDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKTKT---LLKKDKYSLAGGLLGGA-GGG----------VGMSPAGVGQRLESPGGHGGSASAGYAHMNGWANGTYSGQVAAAAAAAAMMQEAQLAYSQHPGSGSHHHHAH---------HHHPHNPQPMHRYDMTALQYSPISNS--QSYMS-----ASPSGYGGISY-----------TQHQNSSVAT--------SAAIGTLSSLVKSEPNISPP-VTTHSRGPC----PGDLREMISMYLPTGESGDPS------VQSRLHALPQHYQS---------TTAGVNGTVPLTHI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2Z1R2-1", "uniprot_id": "SOX1B_DANRE", "id": "Q2Z1R2-1", "name": "Transcription factor Sox-1b", "aln": "---------------------------------------------------------------------------MYSMMMETDLHSPG-AQTNTNT----------GHTGPNSG----------------------SKVNQDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKLMSEAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKTKT---LLKKDKYSLAGGLLAGS-GGGG------GVGLGMGAAGVGQRLESPVGHGGSTAASYAHMNGWTNGAYSGQVAAAAAAAAMMQEAQLAYGQHPGSGAHHHHGH---------HHHPHNPQPMHRYEMTALQYSPLSNS--QSYMS-----ASPSGYGGISY-----------TQHQNSSVAS--------SGAIGALGSLVKSEPSVSPP-VNAHSRAPC----SGDLREMISMYLPTAEAGDPS------VQSRLHAVPQHYQS---------STTSVNGTVPLTHI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0L5T4-1", "uniprot_id": "A0ABK0L5T4_RAT", "id": "A0ABK0L5T4-1", "name": "", "aln": "---------------------------------------------------------------------------MYSMMMETDLHSPGGAQAPTNLS---------GPAGAGGGGGGGGGGGGGGGG---------TKANQDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LLKKDKYSLAGGLLAAG-AGGGGAAVAMGVGVGVGAAAVGQRLESP---GGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNS--QGYMS-----ASPSGYGGIPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPP-APAHSRAPC----PGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQG---------AGAGVNGTVPLTHI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53783-1", "uniprot_id": "SOX1_MOUSE", "id": "P53783-1", "name": "Transcription factor SOX-1", "aln": "---------------------------------------------------------------------------MYSMMMETDLHSPGGAQAPTNLS---------GPAGAGGGGGGGGGGGGGGG----------TKANQDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LLKKDKYSLAGGLLAAG-AGGGGAAVAMGVGVGVGAAAVGQRLESP---GGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNS--QGYMS-----ASPSGYGGIPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPP-APAHSRAPC----PGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQG---------AGAGVNGTVPLTHI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00570-1", "uniprot_id": "SOX1_HUMAN", "id": "O00570-1", "name": "Transcription factor SOX-1", "aln": "---------------------------------------------------------------------------MYSMMMETDLHSPGGAQAPTNLS---------GPAGAGGGGGGGGGGGGGGG----------AKANQDRVKRPMNAFMVWSRGQRRKMAQENPKM-----HNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT---LLKKDKYSLAGGLLAAG-AGGGGAAVAMGVGVGVGAAAVGQRLESP---GGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNS--QGYMS-----ASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPP-APAHSRAPC----PGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQG---------AGAGVNGTVPLTHI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24533-1", "uniprot_id": "DICH_DROME", "id": "Q24533-1", "name": "SOX domain-containing protein dichaete", "aln": "--MATLSTHPNYGFHLGQAQGLEDYAPQSQLQLSPGMDMDIKRVLHYSQSLAAMGGSPNGPAGQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSGLNSSSGHQSAG-MHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKM-----HNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKN---PLTAG---PQGGLQMQAG-------------------GMGQQKLG-------------AGPGAGAGGYN-------------PFHQLPPYFAPSHHLDQG----------------YPVPYFGGFDPLALSKLHQSQAAAAAAVN---------------------------NQGQQQGQAPP----QLPPTSLSSFYSGIYSGISAPSLYAAHSANAAG-------LYPSSSTSSP--------------GSSPGTITPNGMDG--------SMDSALRRPVPVLY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25042-1", "uniprot_id": "ROX1_YEAST", "id": "P25042-1", "name": "Repressor ROX1", "aln": "------------------------------------------------------------------------------------MNPKS---------------------------------------------------STPKIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQKEQQQQKQSQPQLQQPFNNNIVLMKRAHSLSPS----SSVSSSNSYQFQLNNDLKRLPIPSVNTSNYMVSRSLSGLPLTHDKTARDLPQLSSQLNSIPYYSAPHDPSTRHHYLNVAQAQPRANSTPQLPFISSIINNSSQTPVTTTTTS----------TTTATSSPGKFSSSPNSSVLENNRLNSINNSNQYLPPPLLPSLQDFQLD--QYQQLKQMGPTYIVKPLSHTRNNLLSTTTPTHHHIPHIPNQNIPLHQIINSSNTEVTAKTSLVSPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :: ** ***::: : :* : : . ***:*** :*:.** : :* : : *:: : * :::*:***:* **.*. :. : . . : . . :. . . : * : .. * . :. : .: ", "identical_positions": 28, "similar_positions": 53, "identity": "5.39%" }, { "cls_id": "homologset.agr.FB:FBgn0000414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJH2-1", "uniprot_id": "DAB1_RAT", "id": "Q8CJH2-1", "name": "Disabled homolog 1", "aln": "---------MSTETELQVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGK-EGNHRFVAIKTAQAAEPVILDLRDLFQLIYELKQ------REELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAG------------------------------------------------------------------------------------------------------------------------HEP------------------------------------------IRDPETEENIYQVPTSQKKEGVYDVPKSQP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSAVTQLELFGDMSTPPDIT------SPPTPATPGDAFLPAPSQTLPGSADVFGSMSFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQIAMGAQPP--VAQVIPG-----------------------------------------------AQPIAWGQPGLFPATQQPWPTVAG--------------------------------QFPPAAFMPTQTVMPLPAAMFQGPLTPLAT--------------------------------------------------------------VPGTNDSARSSPQSDK----PRQKMG--KEMFKDFQMAQPPP--------------------------------VPSRKPDQPSLTCTSEAFSSYFN-----------------------------KVGVAQDTDDCDDFDISQLNLTPVTSTTPS----------TNSPPTPAPRQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------SPSKSSASHVSDPTADDIFEEGFESPSKSEEQEAP-DGSQA---------------------------------------------------------------------------------------------------SSTSDPFGEP----SGEPSG-DNISPQDGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97318-1", "uniprot_id": "DAB1_MOUSE", "id": "P97318-1", "name": "Disabled homolog 1", "aln": "---------MSTETELQVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGK-EGNHRFVAIKTAQAAEPVILDLRDLFQLIYELKQ------REELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAG------------------------------------------------------------------------------------------------------------------------HEP------------------------------------------IRDPETEENIYQVPTSQKKEGVYDVPKSQPNSQ--PLEDFESRFAAATPNRNLSMDFDELLEATK-------------------------------------------------------------------------------------------------------------------------------------------VSAVTQLELFGDMSTPPDIT------SPPTPATPGDAFLPSSSQTLPGSADVFGSMSFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQIAMGAQPP--VAQVIPG-----------------------------------------------AQPIAWGQPGLFPATQQAWPTVAG--------------------------------QFPPAAFMPTQTVMPLAAAMFQGPLTPLAT--------------------------------------------------------------VPGTNDSARSSPQSDK----PRQKMG--KESFKDFQMVQPPP--------------------------------VPSRKPDQPSLTCTSEAFSSYFN-----------------------------KVGVAQDTDDCDDFDISQLNLTPVTSTTPS----------TNSPPTPAPRQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------SPSKSSASHVSDPTADDIFEEGFESPSKSEEQEAP-DGSQA---------------------------------------------------------------------------------------------------SSTSDPFGEP----SGEPSG-DNISPQDGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75553-1", "uniprot_id": "DAB1_HUMAN", "id": "O75553-1", "name": "Disabled homolog 1", "aln": "---------MSTETELQVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGK-EGNHRFVAIKTAQAAEPVILDLRDLFQLIYELKQ------REELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAG------------------------------------------------------------------------------------------------------------------------HEP------------------------------------------IRDPETEENIYQVPTSQKKEGVYDVPKSQPVSNGYSFEDFEERFAAATPNRNLPTDFDEIFEA---------------------------------------------------------------------------------------------------------------------------------------------TKAVTQLELFGDMSTPPDIT------SPPTPATPGDAFIPSSSQTLPASADVFSSVPFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQMVMGAQPP--VAQVMPG-----------------------------------------------AQPIAWGQPGLFPATQQPWPTVAG--------------------------------QFPPAAFMPTQTVMPLPAAMFQGPLTPLAT--------------------------------------------------------------VPGTSDSTRSSPQTDK----PRQKMG--KETFKDFQMAQPPP--------------------------------VPSRKPDQPSLTCTSEAFSSYFN-----------------------------KVGVAQDTDDCDDFDISQLNLTPVTSTTPS----------TNSPPTPAPRQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------SPSKSSASHASDPTTDDIFEEGFESPSKSEEQEAP-DGSQA---------------------------------------------------------------------------------------------------SSNSDPFGEP----SGEPSG-DNISPQAGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AW18-1", "uniprot_id": "A0A8M3AW18_DANRE", "id": "A0A8M3AW18-1", "name": "", "aln": "---------MSTEAELQPAARPSVRKDSKKRGQDRSEAALIKRFKGDGVRYKAKLIGIDEVTAARGDKLCQDSMMKLKGIAASARSKGEHKQKVFLTVSFGGIKIFDEKSGVLQHHHAVHEISYIAKDITDHRAFGYVCGK-EGNHRFVAIKTAQSAEPVILDLRDLFQLIYEIKQ------REEIEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAG------------------------------------------------------------------------------------------------------------------------HEP------------------------------------------IRDP-SEESIYQVPTSQQKEGVYDVPKRHPNKH-------------KEQLDLLDLDTDVLLLT----------------------------------------------------------------------------------------------------------------------------------------------QNINQLELFGDMSTPPDIT------SPSTPASPANTLDPLLAHQTP--SELFT--PFNPASVPSGYVTMGAVPPAWAQQQFAAQAPLAFGVQSPVQVAQVLPG-----------------------------------------------TQPLIWGQANLFPATQQQWAAMAGA-------------------------------HFSPAAFMPAQTVGPLPAAMFQ-TLAPMAVPASC------------------------------------------------ETPTAAMGGAVAGTSASTASSPQHGERTLQRQAKMS--KEMFKEFQMAKPPA--------------------------------MPARKGEQPSLSCTTDAFSSYFS-----------------------------RVGMAQDTDDCDDFDISQMNLTPVTSTTPS----------TNSPPTPAPRQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------SPSKS-SSHASDPPTDDSFGEAEGSPSRSGEEDAAGDCPQS---------------------------------------------------------------------------------------------------PGASEPQAEPESSETDSPQGKDPLYAQINKGKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P98081-1", "uniprot_id": "DAB_DROME", "id": "P98081-1", "name": "Protein disabled", "aln": "MVKSLVAKLSTASSNLSLASTFGGGSGAAEETNYAKHRNDPGRFFGDGVQFKAKLIGILEVGEARGDRMCQEALQDLK---MAIRAAGEHKQRITIHVTIDGLRLRDEKTGDSLYHHPVHKISFIAQDMTDSRAFGYIFGSPDSGHRFFGIKTDKAASQVVLAMRDLFQVVFELKKKEIEMARQQIQGKSLHDHSSQLASLSSLKSSGLGGMGLGHSDLASGGISSGHALTLLGSSLSTTNGTSRLGVSLDVAKASGSAAKEVSPESVADLVDLEQELTSLQRGISQMERITPNEPTTSSTGGAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPPDSGRNRHKPPNKTPDAVTSLDAMLSPPPGTSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVSSSGLGSVLAMAPLASSESTATPTQQLTEVAAGSGPLADLDIGLSTALGNEEQTSTILSLDAFTDLDPLGTGRTRPYVDKKYFFQELKNPPKKLLKELSSGSQAGLGLGLSLGQLDGLFPEDSTTISTTTTTATNITAGNPQQNSANTLTSTASTAASLGQLLSTVALNPDPLPAPISIPTSISHSITPSAELKLLLGHVTNPPNPTGHYYTTEPPTLNSLENPHPPADPVLLPRDTDPFSPTRKKSDPDPFQESDLFAKLDAFEFEAPPAVPAPSIPNLATETKANVFNGPLQVQLPPEKELQLQQPPSTVRNRPTASVSALPSGGALDVISSISNKKMPHLFGQARSFGKSGSDIGSSVNMRRLQESDSLSETEAAPEPPPRPDSTPYSEPPPLPPKKQFSDLVIRPSPANTTQPPTSGRYEYLNSNVTARRTASSVDAPPIPLPSRRVGRSDGCFPGPGRPRKPGHTEDDYLAPLGAPPPLLPPPSQGSSARARPQRQASLGRPQDIYENKAEILQAQAQAQAQAPEVAPSSNTLAPDITLTQLLTLGMDDLAIKLNVPASKLSTMTLVQLTAYLSEYLSSEKSQVHSQERRSSPANTAPAPASTAAVFKVNFDQQTSFVAKFDDTFGEDEPVMPSGSSDSTFVANFANFNDAPTPVPTVSPVVATVPSADRYAVFREIIDQELQQQQQETDLMGDLTPPPVDETQAKEISEGLEVNNVGAELPIDALDVKPAPKIDTKITEVVAQAKDRYAALRDIILVENLFDKPAIATDTQPEKEKDLLQDFPEFSDEFNEDHDLRQIMDHQNVQTHARDRHGLVDSRGFPTEPSSSALTVGDYDEDEDADAGGESSLDSNEKDAEPVSGQDQYEKLSTSTQQLDAAAPALEDVQQLQQQSLPPKQDQKFLSILTAPGGGTKDDIEIDELMHRAISNLSLDSRDRVSPATSSAAPSRGAPGLHTPSQFNDVSTSPIPLQKPGMGPSPVPSQLSAVSQLIDTATKQMMGDKDREKQSWATFDSPKAKGKARLTLPPPPPPASNTSQPDTVESPCSSDPRDDGWSKQQRRWAKKERQQTSSSSRDLSPWDDETPEYLKRRQLAAAQMAHPHQPPMQAPPQHTDRHGYYMRHARRMNSCDEDYDYDGEFVARRDQPQHQQQQRKFKHGLSRSRDNFELESPSWYHHPAHHTWSPQEIEQVRVRSFDRTAYERSSYGPPPPIYDKRGQLRGKYRGDHRDRERERDRDREYRDYARPSYDFDYENVYEERGGRSPLAYKPGRGGGDYLYDRERDRDRERDRKSFDRESLESYESATRRRRSFGSGNDVYGSLDSRDDYRGDRERDRERDREQMKTRSLRKPTTTSGKLRISGDIDYEQDSEQDFQQRSGVRSLQRPNQLGGDVVLPSNAVVGPQRLRKSSGSSPWDGEEPALPGQKSWKRPASAAETERRLAESRRAVALGQTPSDGEKERRFRKKTRARSAKDLATVGAPSASTSAPSRSSYGRGIRDNYDYICPGQRNDDDDDDDEDYVDDEPPTDEDKFERLNRRRHEMHQRMLESERRQMERHQPPSLAKLPGQNRTRGVVANSDYGFVDSYEQTPTPTPRSNASSTGPGGLMMSGGESSAGVTSSKFNFDDGFESDFNQSSPPPAPAGTASSCNSTPAGPVSANANNGGSKSLFRFSNDFSDREKREQFEMDTPPTSTPPITQKLRFDDNVKVSQFDDAAFEDDFAKASFDFEKEQAGSATAGAGGSGAMSRKQNMRTSKLQQRQELIKKSESVNIFAKKQEDPFEDDEFFKSPDQEQAMDQHNDDTEGGKFQWSEDANFAKFDENM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.::*. * . ..: :. : .. ** *:**::******* ** ****::**::: .** . *: *****:: : :::.*::: ***:* :**.**:**:**:*:** *****: *. :..***..*** ::*. *:* :*****:::*:*: *:::: *: :*:..: * .:: ...: . : : :* *:* ::: ::.:::... ...*: .* * *:*.::.**: * .*.* : :. * . * :: * . . * : * :: : . : .. *:*: * * :**. * : . : .. :.* :. .: * .* * . : .. . *: : ** : * :: .:. . :*: * . :* : :*.*:. :*.. *:*. .** : : ** .: .* *..***.* * : ..* : ..* *: . *. * *::* * . . * :* : *. . : .. ", "identical_positions": 135, "similar_positions": 196, "identity": "6.06%" }, { "cls_id": "homologset.agr.FB:FBgn0000416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10960-1", "uniprot_id": "SAP_RAT", "id": "P10960-1", "name": "Prosaposin", "aln": "-------MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWS---KPTAKSLPCDICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMS-NPGEVCSALNLC-----QSLQEYLAEQN-QRQLESNKIPEVDLARVVAP-------------------------------------------FMSNIPLLLY---------------------------------PQDRPRSQPQPKANEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMMHMQ---PKEICVMVGFCDEVKRVPMRTL----------------------------------VPATEAIKNILPALELTDPYEQDVIQAQNVIFCQVCQLVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCGVISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKN--------------------------------------------------------------------------------------------------------GGFCEVCKKLVIYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKIGVCPSAYKLLLGTEKCVWGPGYWCQNSE---------------------------------------TAARCNAVDHCKRHVWN-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61207-1", "uniprot_id": "SAP_MOUSE", "id": "Q61207-1", "name": "Prosaposin", "aln": "-------MYALALFASLLATALTSPVQDPKTCSGGSAVLCRDVKTAVDCGAVKHCQQMVWS---KPTAKSLPCDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIKGEMS-NPGEVCSALNLC-----QSLQEYLAEQN-QKQLESNKIPEVDMARVVAP-------------------------------------------FMSNIPLLLY---------------------------------PQDHPRSQPQPKANEDVCQDCMKLVSDVQTAVKTNSSFIQGFVDHVKEDCDRLGPGVSDICKNYVDQYSEVCVQMLMHMQDQQPKEICVLAGFCNEVKRVPMKTL----------------------------------VPATETIKNILPALEMMDPYEQNLVQAHNVILCQTCQFVMNKFSELIVNNATEELLVKGLSNACALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLKEPTPPKQPAQPKQSALPAHVPPQKN--------------------------------------------------------------------------------------------------------GGFCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVEVMDPGFVCSKIGVCPSAYKLLLGTEKCVWGPSYWCQNME---------------------------------------TAARCNAVDHCKRHVWN-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07602-1", "uniprot_id": "SAP_HUMAN", "id": "P07602-1", "name": "Prosaposin", "aln": "-------MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWN---KPTVKSLPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMS-RPGEVCSALNLC-----ESLQKHLAELNHQKQLESNKIPELDMTEVVAP-------------------------------------------FMANIPLLLY---------------------------------PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQ---PKEICALVGFCDEVKEMPMQTL----------------------------------VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG-------------------------------TRLPALTVHVTQPKD--------------------------------------------------------------------------------------------------------GGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTE---------------------------------------TAAQCNAVEHCKRHVWN-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R3X1-1", "uniprot_id": "M0R3X1_RAT", "id": "M0R3X1-1", "name": "Proactivator polypeptide-like 1", "aln": "---MNIMLCVLILWSGLLGATKASPISVPHECAKGSEVWCQDLQAAARCRAVRHCQSAVWS---KPTVKSLPCSVCQDVAAAASNGVNPDAKESDILASVMKTCEWLPSQESSAKCKWMVDNHSAAVLVMLRGAPGTALASVCTALTLC-----EPLQRHLAVATSERPLTQE-----DANEVMAP-------------------------------------------FLSNGALTFH---------------------------------PSQMP--------VGAVCHDCVQLISRLQSALESNLTLAE---VTVQNQCQSMGPGLAALCENYVHWQFVPAKQALQTLP---PQEVCRKGGFCEEQRESAHW-------------------------------------LAQVAAVDGVPSLEMELPKK-NELQMQLGLTCDVCLNVVQELDKWLETNSTEALISHALERVCSIMPESLVQQCITLVDTYGPNLVQ-LVSKVTPEKVCETIRLCGSKRQ----------------------ARSISRVATTTPPLLMDEENQ--------------------------------------------------------------------------------------------------------GSFCQGCKRLLGVSSQNLDRKSTKRDILNAFKGGCRILPLPYVLQCNRFVAEYEPVLIESLRFMMNPTDLCKKMGACHGPKVPLLGTDQCVMGPRFWCKSPE---------------------------------------AAEMCDALEHCQRLVWKKPISRTNEQP---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1C1-1", "uniprot_id": "SAPL1_MOUSE", "id": "Q8C1C1-1", "name": "Proactivator polypeptide-like 1", "aln": "------MLCALILWSGLLGAARASPISVPRECAKGSEVWCQDLQAAAKCRAVRHCQSAVWN---KPTVKSLPCSVCQDVAAAAGNGVNPGATESDILTSVMKTCEWLPSQESSAKCKWMVNNHSAAVLSMLSGAQETDLASVCTALTLC-----EPLQRHLAETTSERPLTQE-----DANEVMAP-------------------------------------------FLSNGALSFH---------------------------------PSQMP--------EGAVCHDCVQLISLLQDALESNLTLAE---VTVQNQCQSMGPGLAALCENYIHRQFVPAKQTLQGLP---PQEVCRKGGFCE--RESAHW-------------------------------------LTRVAAVDGVPSLEMEMPRT-NELQMQLGLTCDVCLNLVQELDKWLVTNSTEALISHTLERVCTVVPEPLVQQCITLVDTYSPELVQ-LMSKVTPEKVCETIKLCGSKRR----------------------ARSISRAVATTPSLPVDEENQ--------------------------------------------------------------------------------------------------------GSFCQGCKRLLGMSSQNLDHKSTKRDILNAFKGGCRILPLPYVMQCNRFVAEYEPVLIESLKFMMNPTDLCKKMGACHGPKTPLLGTDQCVMGPSFWCKSPE---------------------------------------AAEMCNALEHCQRLVWKKPVSKINEQP---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUJ1-1", "uniprot_id": "SAPL1_HUMAN", "id": "Q6NUJ1-1", "name": "Proactivator polypeptide-like 1", "aln": "------MLCALLLLPSLLGATRASPTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWN---KPTAKSLPCDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALSLC-----EPLQRHLAT---LRPLSKE-----DTFEAVAP-------------------------------------------FMANGPLTFH---------------------------------PRQAP--------EGALCQDCVRQVSRLQEAVRSNLTLAD---LNIQEQCESLGPGLAVLCKNYLFQFFVPADQALRLLP---PQELCRKGGFCEELGAPAR--------------------------------------LTQVVAMDGVPSLELGLPRKQSEMQMKAGVTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVAKITPEKVCKFIRLCGNRRR----------------------ARAVHDAYAIVPSPEWDAENQ--------------------------------------------------------------------------------------------------------GSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGACHGPRTPLLGTDQCALGPSFWCRSQE---------------------------------------AAKLCNAVQHCQKHVWKEMHLHAGEHA---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y125-1", "uniprot_id": "Q9Y125_DROME", "id": "Q9Y125-1", "name": "", "aln": "-MERAGLLAVLALCCAFGVFAAATPLLGSSKCTWGPSYWCGNFSNSKECRATRHCIQTVWETQKVPVDTDSICTICKDMVTQARDQLKSNQTEEELKEVFEGSCKLIPIKPIQKECIKVADDFLPELVEALASQMN--PDQVCSVAGLCNSARIDELYKNGIQAGLDGTVQNEDDSSEETELAMQPNQLSCGNCNLLSRLMHSKFAATDRDDMVETMLHMCGSLSSFSDACANIVLTYFNDIYDHVSKHLTTDAVCHVSGVCASRYHQHEEEKQPQEALVALDAGDDIPCELCEQLVKHLRDVLVANTTETEF--KQVMEGFCKQSKGFKDECLSIVDQYYHVIYETLVSKLD--ANGACCMIGICQKNSASSMKDVPIMPLLPVIEPAQVKITIEKLEKHEKKQLGASEPKFSQQEILDMQLPIDHLMGAANPGALVEGGELCTLCEYMLHFIQETLATPSTDDEIKHTVENICAKLPSGVAGQCRNFVEMYGDAVIALLVQGLNPRDVCPLMQMCPKNLPKKEDVEVFNPQPASDEQDPPTCPLCLFAVEQAQMKIRDNKSKDNIKKVLNGLCSHLPNEIKEECVDFVNTYSNELIDMLITDFKPQEICVQLKLCPKTTYALWDLRISLEDDVDGEDKSSSEEISFNDIESLEELPPQLAFDPGFTAAPNCLICEELVKTLEKRMGKHPTRDSIKHILEESCDRMRKPMNTKCHKVIDKYGDKIADLLLKEMDPKLICTELGMCILADLDDLEVDEALKYDVIALPRQDNKLSSSIKEPPTCVLCEFIMTKLDADLKNKTEQDDIKRAIEAVCNRLPATVRKQCDTFVDGYASAVLKLLSDVPPKQVCQKLQLCFSVAVTDEVLECGVCHGVTQALLPFLREKKDNVSEVTALQMTSVGCENLPAKYYKICSEMISIYGSSIKNLAKRPYIDQSHICAEIGKCFESEKSSLAFARISA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07988-1", "uniprot_id": "PSPB_HUMAN", "id": "P07988-1", "name": "Pulmonary surfactant-associated protein B", "aln": "MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWG----HVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTD--SNGICMHLGLCK----------------SRQPEP-------------------------------------------------------------------------------------------------------------------------------------------------------EQEPGMSDPLPKPLRDPLPDPLLDKLVLP------------------------------------------------------------VLPGALQARPGPHTQDLSEQQFPIPLP---YCWLCRALIKRIQAMIPKG----ALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDS---------------------------AGPRSPTGEWLPRDSE-----------------------------------------------------------------------------------------------------------CHLCMSVTTQAG-----NSSEQAIPQAMLQACVGS-WLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG----TMSSPLQCIHSPDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : : *: *. * ... : * * :* ** . . * *: :. . : :. : . * : * : : . . :: : . :* ** *. . : . * * ::. . : . : . . * :* * . :. :: :: : * :* : * .: * * : :.:. * : .* :*. .: :: : : :. * :* * :. ", "identical_positions": 34, "similar_positions": 76, "identity": "3.54%" }, { "cls_id": "homologset.agr.FB:FBgn0000422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14173-1", "uniprot_id": "DDC_RAT", "id": "P14173-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "-----------------------------------MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRALIPTTAPQEPETYEDIIRDIEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKMIRQLQAASPELTQAALMEKLVAYTSDQAHSSVERAGLIGGVKIKAIPSDGNYSMRAAALREALERDKAAGLIPFFVVVTLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTEAFNMDPVYLRHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVKLSHEFESLVRQDPRFEICTEVILGLVCFRLKGSNQLNETLLQRINSAKKIHLVPCRLRDKFVLRFAVCSRTVESAHVQLAWEHIRDLASSVLRAEKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88533-1", "uniprot_id": "DDC_MOUSE", "id": "O88533-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "-----------------------------------MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRPLIPATAPQEPETYEDIIKDIEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKVIRQLQAASPEFTQAAIMEKLVAYTSDQAHSSVERAGLIGGIKLKAVPSDGNFSMRASALREALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRTDLTGAFNMDPVYLKHSHQDSGFITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVELSHEFESLVRQDPRFEICTEVILGLVCFRLKGSNELNETLLQRINSAKKIHLVPCRLRDKFVLRFAVCARTVESAHVQLAWEHISDLASSVLRAEKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20711-1", "uniprot_id": "DDC_HUMAN", "id": "P20711-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "-----------------------------------MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05031-1", "uniprot_id": "DDC_DROME", "id": "P05031-1", "name": "Aromatic-L-amino-acid decarboxylase", "aln": "MSHIPISNTIPTKQTDGNGKANISPDKLDPKVSIDMEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSDQAHSSVERAGLLGGVKLRSVQSE-NHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFNVDPLYLKHDMQGS--APDYRHWQIPLGRRFRALKLWFVLRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCFRLKGSNERNEALLKRINGRGHIHLVPAKIKDVYFLRMAICSRFTQSEDMEYSWKEVSAAADEMEQEQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: **: .* ***::*:*::.*. * * *:*:****:.*** :**::*:.::*::.*:*::*********** *.******.****::****.***.****:* *********.************* ** .*:*******:***:******.*::* ::.:: ** : ::: ***.* *************:**:*:::: *: *. **.:**.:*:*:* * *****: *.*****..*:** * * **: *:..:*:*:*************:*:*::*:* ***********:**********:* : :. **.:** **:*. *.* .**************:**:***:*:***:.***:**:* :::::* .* *.***:..*: :***********: **:**:***. :*****.:::* :.**:*:*:* .:* .:: :*:.: * .: : : ", "identical_positions": 273, "similar_positions": 142, "identity": "53.01%" }, { "cls_id": "homologset.agr.FB:FBgn0000426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62306-1", "uniprot_id": "RUXF_HUMAN", "id": "P62306-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MS--LPLNPKPFLNGLTGKPVMVKLKWG-MEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62307-1", "uniprot_id": "RUXF_MOUSE", "id": "P62307-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MS--LPLNPKPFLNGLTGKPVMVKLKWG-MEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AAT4-1", "uniprot_id": "D4AAT4_RAT", "id": "D4AAT4-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MS--LPLNPKPFLNGLTGKPVMVKLKWG-MEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24297-1", "uniprot_id": "RUXF_DROME", "id": "Q24297-1", "name": "Small nuclear ribonucleoprotein F", "aln": "------MSAGMPINPKPFLNGLTGKPVLVKLKWG-QEYKGFLVSVDGYMNMQLANTEEVIEGSVTGNLGEVLIRCNNVLYIKGMEDDDEEGEMRD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54999-1", "uniprot_id": "RUXF_YEAST", "id": "P54999-1", "name": "Small nuclear ribonucleoprotein F", "aln": "MSESSDISAMQPVNPKPFLKGLVNHRVGVKLKFNSTEYRGTLVSTDNYFNLQLNEAEEFVAGVSHGTLGEIFIRCNNVLYIR---------ELPN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *:******:**..: * ****:. **:* ***.*.*:*:** ::** : * * ***::*********: *: :", "identical_positions": 43, "similar_positions": 21, "identity": "45.26%" }, { "cls_id": "homologset.agr.FB:FBgn0000439", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACE1-1", "uniprot_id": "D4ACE1_RAT", "id": "D4ACE1-1", "name": "Homeobox protein Hox-D4", "aln": "MAMSSYMVNS--------------KYVDPKFPP-CEEYLQGG-----------------------------------YLGEQGAD------------------------YYGSGAQGSDFQPPGLYPRP----DFGEQPFGGGGPGPGSALP----------------------ARGHGQEPSGPGSHYSAPGE-----------------------------PCPAP---PPAPLPGARACSQPTGPKQPPPGTALKQPA-----------------------------------------------------------------------------------------VVYPWMKKVHVN-SVNPNYT-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSS--CSSSAAPS---------QHLQPMAKDHHTDLTTL--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10628-1", "uniprot_id": "HXD4_MOUSE", "id": "P10628-1", "name": "Homeobox protein Hox-D4", "aln": "MAMSSYMVNS--------------KYVDPKFPP-CEEYLQGG-----------------------------------YLGEQGAD------------------------YYGSGAQGADFQPSGLYPRP----DFGEQPFGGGGPGPGSALP----------------------ARGHGQEPSGPGSHYGAPGE-----------------------------RCPAP---PPAPLPGARACSQPTGPKQPPPGTALKQPA-----------------------------------------------------------------------------------------VVYPWMKKVHVN-SVNPNYT-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSS---CSSSAAPG---------QHLQPMAKDHHTDLTTL--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09016-1", "uniprot_id": "HXD4_HUMAN", "id": "P09016-1", "name": "Homeobox protein Hox-D4", "aln": "MVMSSYMVNS--------------KYVDPKFPP-CEEYLQGG-----------------------------------YLGEQGAD------------------------YYGGGAQGADFQPPGLYPRP----DFGEQPFGGSGPGPGSALP----------------------ARGHGQEPGGPGGHYAAPGE-----------------------------PCPAPPAPPPAPLPGARAYSQ-SDPKQPPSGTALKQPA-----------------------------------------------------------------------------------------VVYPWMKKVHVN-SVNPNYT-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPS---------QHLQPMAKDHHTDLTTL--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57374-1", "uniprot_id": "HXD4A_DANRE", "id": "O57374-1", "name": "Homeobox protein Hox-D4a", "aln": "MAMSSYMVNS--------------KYVDPKFPP-CEEYSQNS-----------------------------------YIPEQSPG------------------------YYSP-SQDTDFQHPGIYSRS----NYSEQPYICS-TVQGSSVQ----------------------PRGHVQDQASTPSPFPAQTE-----------------------------QCPAV------QISGSRTCGQQQNTKTQN-GIPTKQPA-----------------------------------------------------------------------------------------VVYPWMKKVHVT-TVNPDYT-GPEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIESAHTLSLSERQIKIWFQNRRMKWKKDHKLPNTKGRSASVGN--------------------QHAQHAQKDSQTEITTL--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17483-1", "uniprot_id": "HXB4_HUMAN", "id": "P17483-1", "name": "Homeobox protein Hox-B4", "aln": "MAMSSFLINS--------------NYVDPKFPP-CEEYSQSD----------------------------------YLPSDHSPG-----------------------YYAGGQRRESSFQPEAGFGRR---AACTVQRYAACRDPGPPPPPPPPPPPPPP---------PGLSPRAPAPPPAG--ALLPEPGQ-----------------------------RCEAVSSSPPPPPCAQNPLHP-SPSHS-----ACKEP------------------------------------------------------------------------------------------VVYPWMRKVHVS-TVNPNYA-GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAAGSAGGPP------------GRPNGGPRAL-----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10284-1", "uniprot_id": "HXB4_MOUSE", "id": "P10284-1", "name": "Homeobox protein Hox-B4", "aln": "MAMSSFLINS--------------NYVDPKFPP-CEEYSQSD----------------------------------YLPSDHSPG-----------------------YYAGGQRRESGFQPEAAFGRR---APCTVQRYAACRDPGPPPPPPPPPPPPPP----------GLSPRAPVQPTAG--ALLPEPGQ-----------------------------RSEAVSSSPPPPPCAQNPLHP-SPSHS-----ACKEP------------------------------------------------------------------------------------------VVYPWMRKVHVS-TVNPNYA-GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGTAGAAGGPP------------GRPNGGPPAL-----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22574-1", "uniprot_id": "HXB4A_DANRE", "id": "P22574-1", "name": "Homeobox protein Hox-B4a", "aln": "MAMSSYLINS--------------NYVDPKFPP-CEEYSQSD----------------------------------YLPS-HSPD-----------------------YYS-AQRQDPSFQHESIYHQR---SGCADPPYSSCQGPGQPAAV--------------------ISPRGHVLPTTALSTPLPEPSH-----------------------------HCDSVTPSPPP-ACGQTPTSQNTSTVS-----SRKDP------------------------------------------------------------------------------------------VVYPWMKKVHVN-IVSPNYS-GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSNSASTNSSGCPTLCSN------QSRASGPPPSL-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00056-1", "uniprot_id": "HXA4_HUMAN", "id": "Q00056-1", "name": "Homeobox protein Hox-A4", "aln": "MTMSSFLINS--------------NYIEPKFPP-FEEYAQHSGSGGADGGP---------------------GGGPGYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKG-------------PAHGLHASHVLQPQLPPPLQPRAVPPAAP-------------------RRCEAAPATPGVPAGGSAPACPLLLADKSPLGLKGKEP------------------------------------------------------------------------------------------VVYPWMKKIHVS-AVNPSYN-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQT------QSPHLHPHPHPSTSTPVPSSI-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06798-1", "uniprot_id": "HXA4_MOUSE", "id": "P06798-1", "name": "Homeobox protein Hox-A4", "aln": "MTMSSFLINS--------------NYIEPKFPP-FEEFAPHGGPGGGDGAV---------------------GGGPGYPRPQSAP--HLPAPN---PHA--ARQPPA-YYAPR-AREPSYPGG-LYPAP---AAACPYACRG-ASPGRPEQS----------------------PAPGAHPSPAPQP--PVPLG-----------------------------HCAPGPTTPAVATGGSAPACPLLLADQGPAGPKGKEP------------------------------------------------------------------------------------------VVYPWMKKIHVS-AVNSSYN-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNTASAPAGPPGKAQT------HSPHHHPHPLPGASTPIPSSI-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PWL5-1", "uniprot_id": "HXA4A_DANRE", "id": "Q9PWL5-1", "name": "Homeobox protein Hox-A4a", "aln": "MIMSSYLINS--------------NYIEPSFPP-CEEYHQNG------YMP---------------------VSSDYYERPKDPG----------FPHH----------------EEASYPRS-NYQEQ-------SYDYGNVSTNDLNDFS----------------------DRHHAQPQSVSQN------------------------------------HGPRLTTESCVGSDGNKDCS--LVSDALPGSQKSKEP------------------------------------------------------------------------------------------VVYPWMKKVHVN-TVTASYS-GGVPKRSRTAYTRQQALELEKEFHFNRYLTRRRRVEIAHTMCLSERQVKIWFQNRRMKWKKDHKLPNTKIRSSSSAPSNH----HVKT------DATQQQQTLLP---TPCSSNL-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09017-1", "uniprot_id": "HXC4_HUMAN", "id": "P09017-1", "name": "Homeobox protein Hox-C4", "aln": "MIMSSYLMDS--------------NYIDPKFPP-CEEYSQNS-----------------------------------YIPEHSPE-----------------------YYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHG-----------------PAQAGHHHPEKSQSLCEPAPLS-----------------------------GASASPSPAPPACSQPAPDHP-SSAAS-------KQP------------------------------------------------------------------------------------------IVYPWMKKIHVS-TVNPNYN-GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP--STLSAA----TPGTSEDHSQSATPPEQQRAEDITRL----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08624-1", "uniprot_id": "HXC4_MOUSE", "id": "Q08624-1", "name": "Homeobox protein Hox-C4", "aln": "MIMSSYLMDS--------------NYIDPKFPP-CEEYSQNS-----------------------------------YIPEHSPE-----------------------YYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRAHG-----------------PAQAGHHHPEKSQPLCEPAPLS-----------------------------GTSASPSPAPPACSQPAPDHP-SSAAS-------KQP------------------------------------------------------------------------------------------IVYPWMKKIHVS-TVNPNYN-GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP--STLSAA----TPGTSEDHSQSATPPEQQRAEDITRL----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PWM3-1", "uniprot_id": "HXC4A_DANRE", "id": "Q9PWM3-1", "name": "Homeobox protein Hox-C4a", "aln": "MIMSSYLMDS--------------NYIDPKFPP-CEEYSQNS-----------------------------------YIPEHSPE-----------------------YYSRARDSGYQHHHQELYP---PRASYQERQYNCASIPEPDTQRGHG-----------------LPHAGHLLGKGQSASCEPPPLP-----------------------------LSPATPSAASSACNQATPEHPNSSASA-------KQP------------------------------------------------------------------------------------------VVYPWMKKIHVS-TVNSSYN-GAEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLVLSERQIKIWFQNRRMKWKKDHRLPNTKVRSSSSTGISSGSNTSSAAGVVAAASTTNTMSASEDLSGTERGEDITRL----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07548-1", "uniprot_id": "DFD_DROME", "id": "P07548-1", "name": "Homeotic protein deformed", "aln": "--MSSFLMGYPHAPHHVQSPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGGGGAGGMTGHPHSMHPADMVSDYMAHHHNPHS-------HSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQQHLSNNNNNGSGNNNNNNNNNNSNLNNNNNNNQMGHTNLHGHLQQQQSDLMTNLQLHIKQDYDLTAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:::. : ::*.*** ::: . . . .:* ::****:*:** .. .* * ***.******:* ********:*********:* **:: *****:**************::***** ", "identical_positions": 71, "similar_positions": 32, "identity": "11.93%" }, { "cls_id": "homologset.agr.FB:FBgn0000442", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64595-1", "uniprot_id": "KGP2_RAT", "id": "Q64595-1", "name": "cGMP-dependent protein kinase 2", "aln": "MGNGSVKPKHSKHPDGQS-------GNLSNEALRSK---VAELEREVKRKDAELQEREYHLKELREQLAKQTV-AIAELTEELQSK---------CIQLNKLQDVIHVQGGSPLQASPDKVPLDVHRKTSGLVSLHSRRGAKAGVSAE-PTSRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIVKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITN-VKTWALDREVFQNIMRRTAQARDEEYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS-TEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFDELQKYLEGYVATLNRDDEKRHAKRSMSSWKLSKALSLEMIQLKEKVARFSSTSPFQNLEIIATLGVGGFGRVELVKVKNEN--IAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGPIDHSYFDKYPPEKGVPPDEMSGWDKDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61410-1", "uniprot_id": "KGP2_MOUSE", "id": "Q61410-1", "name": "cGMP-dependent protein kinase 2", "aln": "MGNGSVKPKHAKHPDGHS-------GNLSNEALRSK---VLELERELRRKDAELQEREYHLKELREQLAKQTV-AIAELTEELQSK---------CIQLNKLQDVIHVQGGSPLQASPDKVPLDVHRKTSGLVSLHSRRGAKAGVSAE-PTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGEKLSTGSYVIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITN-VKTWALDREVFQNIMRRTAQARDEEYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS-TEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFDELQKYLEGYVATLNRDDEKRHAKRSMSSWKLSKALSLEMIQLKEKVARFSSTSPFQNLEIIATLGVGGFGRVELVKVKNEN--VAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHLLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGPIDHSYFDKYPPEKGVPPDEMSGWDKDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13237-1", "uniprot_id": "KGP2_HUMAN", "id": "Q13237-1", "name": "cGMP-dependent protein kinase 2", "aln": "MGNGSVKPKHSKHPDGHS-------GNLTTDALRNK---VTELERELRRKDAEIQEREYHLKELREQLSKQTV-AIAELTEELQNK---------CIQLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAE-PTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITN-VKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS-TEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDDEKRHAKRSMSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNEN--VAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2S7-1", "uniprot_id": "A0A8M9Q2S7_DANRE", "id": "A0A8M9Q2S7-1", "name": "cGMP-dependent protein kinase", "aln": "MGNGSMKLNPLKQVSGSAKSKNNGESSLVPQVLRVR---VEELETHLKKKDEDLNAKELQIKHLEEQLAQQKQ-TLSEISDTLRSK---------CLQLNKLQDALKSQGELGLLPSPLKEKVSQGLTGLLRETLNRRKGAKAGVSAE-PSSRTYDSSGIPKFYFESARVWKEQSVKKLLTDALNKNQYLRRLEVQQVKDMVECMYERTYQQGEYVIKQGEPGNHLFVLADGKLDVYQHNKLLTSIAVWTTFGELAILYNCTRTASVKAASN-VKTWALDREVFHNIMRMTAEARHEQYRNFLRSVSLLASLPGDKLTKIVDCLEVEYYNKGDYIIREGEEGNTFYIIANGKIKVTQS-TQDHEEPQIINTLGKGDYFGEKALISDDVRSANIIAEEDGVECLVIDRETFSQTVGTFDELKKYLQSYVDSLARDDKKRNAKRSGSCTPPNTPVSHDMIELKERESSFASTIPFTCLEAIATLGVGGFGRVELVKLKNEN--VTFALKCIKKRHIVDNRQEEHIYSERRILLETNCPFIVKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSFEEYTAKFCVGCVTEAFEYLHNNGIIYRDLKPENLMLDTDGYVKLVDFGFAKKLKCGQRTWTFCGTPEYVAPEIILNKGHGLSVDFWSLGILIFELLTGSPPFTGSDQMIIYTFILKGIEKMDFPKKITKRPGDLIRKLCRQNPSERLGNLKNGITDIKKHRWFTGFSWSGLKARNLISPLKREVKGPTDHSYFDSYPPEEEIPPDEMSGWDTDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03042-1", "uniprot_id": "KGP1_DROME", "id": "Q03042-1", "name": "cGMP-dependent protein kinase, isozyme 1", "aln": "MAAGMLTDREREAIVSNLT----KDVQALREMVRSRESELVKLHREIHKLKSVLQQTTNNLNVTRNEKAKKKLYSLPEQCGEQESRNQNPHLCSSCGMVLPTSPEFALEALSLGPLSPLASTSSASPSGRTSADEVRPKAMPAAIKKQGVSAESCVQSMQQSYSIPIPKYEKDFSDKQQIKDAIMDNDFLKNIDASQVRELVDSMYSKSIAAGEFVIREGEVGAHLYVSAAGEFAVMQQGKVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPTSPEETELRTLSRGDYFGEQALINEDKRTANIIALSPGVECLTLDRDSFKRLIGDLCELKE------KDYGDESRKLAMKQAQESCRD---------EPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLNEPPDELSGWDADF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * :. . : . . : :* : : :*. .::: . :: ::: .:: :::. ::.* ..: * : . . :. ** . . :. *.:. : ::.: . .: : .: *: * *: :.**: .*::*:.:: .*::::*:.** .. *.:::::** * *::* * *.: * * *:* .: .:***************::. :: .:.*.***.**::** *. * *: ******.** .*. : *:** * **:*:* * ****:* *.:*:::::*:::***. * : :.** :*:****:***.:* *:***** . .* **.:**::*.: :* : **:: :..* *:: . : **: . : ** ::***:********** :::: **:**::*:****.:*:**::**::*: . .*** ::***::*:**********:***:*::*******:: :::* :.** :**:*** ************:** **:*:*******:: ..:**************:******. :**:*:****:.***.*.***:. * * *.:*****: : **::*:: . :**::***: *:**** ..** *****:*: **.*.** :: * .*: * : * * *** :* : ****:**** **", "identical_positions": 295, "similar_positions": 245, "identity": "37.48%" }, { "cls_id": "homologset.agr.FB:FBgn0000447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63707-1", "uniprot_id": "PYRD_RAT", "id": "Q63707-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MAWRQLR---------KRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFD-KNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELR-HLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELG--IDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35435-1", "uniprot_id": "PYRD_MOUSE", "id": "O35435-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MAWRQLR---------KRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAVRVISLGLLPRATFQDSNMLEVRVLGHKFRNPVGIAAGFD-KHGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSAVEHRLRARQQKQTQLTTDGLPLGINLGKNKTSVDAAADYVEGVRILGPLADYLVVNVSSPNTAGLRSLQGKTELR-RLLSKVLQERDALKGPQKPAVLVKIAPDLTAQDKEDIASVARELG--IDGLIITNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGTIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTFLGPPVVARVKRELEALLKERGFNTVTDAIGVDHRR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02127-1", "uniprot_id": "PYRD_HUMAN", "id": "Q02127-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MAWRHLK---------KRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFD-KHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELR-RLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELG--IDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32748-1", "uniprot_id": "PYRD_DROME", "id": "P32748-1", "name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "aln": "MDQDHLKNAKNATRRVGRLRSLGIVTVGGAALVAGITAYKNQDQLFRTFVMPAVR-LLPAEASHQLAVLACKYRLCPVSQYHDDQNLHTSFFGRMLSNPIGIAAGFD-KNAEAVDGLQDLGFGFIEVGTVTPAAQEGNPKPRVFRLTEDKAIINRYGFNSDGHQAVLQRLRLLRKKE---NFNGV-VGVNLGRNKTTMSPIADYVQGVRVFGPVADYLVINVSSPNTKGLRDMQSKEKLR-ELLEQVNDTKSSLDKNKNVPILLKLSPDLSLDDMKDIVWVIKRKKSRVDGLIVSNTTVSRENIEKNKLAEETGGLSGPPLKARSTEMIAQMYQLTDGKIPIIGVGGVASGYDAYEKIEAGASYVQIYTALVYEGPALVEDIKAELSALITRLGHTNVADVVGTNSKFYLPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28272-1", "uniprot_id": "PYRD_YEAST", "id": "P28272-1", "name": "Dihydroorotate dehydrogenase (fumarate)", "aln": "----------------------------------------------------------------------------------MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFITKSATTLEREGNPEPRYISVP--LGSINSMGLPNEGIDYYLSYVLNRQKNYP------DAPAIFFSVAGMSIDENLNLLRKIQDS-EFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFFKKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKP---KNGFGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:.. **. *:*.. : :* * . * . :.*. :****.** : :. . ** *: ..* . : ::: .: :. : . : . :: . . :*:*.**. * .: . .* . * :* . : . : *: . ::: . . :.. :. :. . . **:.* :: : : :* : :**.**: ** ** *:: .*** :*: * * * :. :: **. :: *. : : * ", "identical_positions": 52, "similar_positions": 98, "identity": "12.62%" }, { "cls_id": "homologset.agr.FB:FBgn0000448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M9J5-1", "uniprot_id": "A0ABK0M9J5_RAT", "id": "A0ABK0M9J5-1", "name": "", "aln": "MESAPAAPDPAASEPGSSGSEAAAGSRETPLTQDAGRKSEAPGAGRRQSYASSSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQ--QQ------------------------QRDHQQQPGEAEPLTPTYNISA-NGLTELHDDLST-YMDGHTPEGSKADSAVSSFYLD-IQPSPDQSGLD-INGIK---PEPICDYT-------------PASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCE--DFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKN----HREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51448-1", "uniprot_id": "RORA_MOUSE", "id": "P51448-1", "name": "Nuclear receptor ROR-alpha", "aln": "MESAPAAPDPAASEPGSSGSEAAAGSRETPLTQDTGRKSEAPGAGRRQSYASSSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQ--QQ------------------------QRDHQQQPGEAEPLTPTYNISA-NGLTELHDDLST-YMDGHTPEGSKADSAVSSFYLD-IQPSPDQSGLD-INGIK---PEPICDYT-------------PASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCE--DFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKN----HREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35398-2", "uniprot_id": "RORA_HUMAN", "id": "P35398-2", "name": "Nuclear receptor ROR-alpha", "aln": "MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQ--QQ------------------------QRDHQQQPGEAEPLTPTYNISA-NGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLD-IQPSPDQSGLD-INGIK---PEPICDYT-------------PASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCE--DFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKN----HREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QLY4-1", "uniprot_id": "RORAA_DANRE", "id": "F1QLY4-1", "name": "Nuclear receptor ROR-alpha A", "aln": "-----------------------------------------------MMYFVIS--------AMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQ--QQ------------------------QRDHQQQPGEAEPLTPTYGLST-NGLTELHDDLSG-YMNGHTPDGTKPDSGVSSFYLD-IQPSPDQSGLD-INGIK---PEPICDFT-------------PGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCD--DLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKN----HREDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QJF4-1", "uniprot_id": "RORAB_DANRE", "id": "F1QJF4-1", "name": "Nuclear receptor ROR-alpha B", "aln": "------------------------------------------------MYLMIT--------AMKAQIESIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQGTVSYSCPRQKSCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLFAEVQKHRQQ--QQDDKTGDE---------------SEKNQESQAPGEAEPLTPSYALSS-SGVTEIPDDLSG-YVNGQTQEEGKADSAIGGFYLD-IQPSPDQSGLD-MDGIK---LEPVCDLS-------------SDSGLDQYCCYSNGDASP--PHDDLEHLSENICKSHLETCQYLREELQPSNWQTVLQSNLEAYQKKSQEDMWQLCAVKVTEAVQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAYNSQNNTVFFDSKYAGPEVFKALGCD--DLISSVFEFAKSLNSLQLSEDEIGLFSAYVLMSADRSWLQEKTRVEKLQQKIKIALQNLLQKN----KRDEGILTKLVCKVSTVRMLCRRHMEKLSAFRALYPEMVHTRFPPLYKELFGSDFEQILPQEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45446-2", "uniprot_id": "RORB_RAT", "id": "P45446-2", "name": "Nuclear receptor ROR-beta", "aln": "------------------------------------------------MCENQLK----TKADGTAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQR--LQ-------------------------EQRQQQSGEAEALARVYSSSISNGLSNLNTETGGTYANGHVIDLPKSE---GYYNIDSGQPSPDQSGLD-MTGIKQIKQEPIYDLT-------------SVHNLFTYSSFNNGQLAPGITMSEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSD--DLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLLEPRKVQKLQEKIYFALQHVIQKN----HLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPDIVNTLFPPLYKELFNPDCAAVCK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1B8-2", "uniprot_id": "RORB_MOUSE", "id": "Q8R1B8-2", "name": "Nuclear receptor ROR-beta", "aln": "------------------------------------------------MCENQPK----TKADGTAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQR--LQ-------------------------EQRQQQSGEAEALARVYSSSISNGLSNLNTETGGTYANGHVIDLPKSE---GYYSIDSGQPSPDQSGLD-MTGIKQIKQEPIYDLT-------------SVPNLFTYSSFNNGQLAPGITMSEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSD--DLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKN----HLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPDIVNTLFPPLYKELFNPDCAAVCK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92753-2", "uniprot_id": "RORB_HUMAN", "id": "Q92753-2", "name": "Nuclear receptor ROR-beta", "aln": "------------------------------------------------MCENQLK----TKADATAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQR--LQ-------------------------EQRQQQSGEAEALARVYSSSISNGLSNLNNETSGTYANGHVIDLPKSE---GYYNVDSGQPSPDQSGLD-MTGIKQIKQEPIYDLT-------------SVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSD--DLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKN----HLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZN69-1", "uniprot_id": "A0A8I5ZN69_RAT", "id": "A0A8I5ZN69-1", "name": "", "aln": "---------------------------------------------------------------MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ--QQQREQVAKTPPAGSHGADTLTYTLGVPDGQLPLGASPDLPEAS--ACPPGLLRASGSGPP-YSN-TLAKTEVQG---ASCHLEYSPERGKAEGRDSIYSTDGQLTLGRRGL--------QLGEPEQGSDSHCSPSFCSAPEAPYASLTDIEYLVQNVCKSYRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLKAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCS--ELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKT----HRQ-GLLAKLPPKG-KLRSLCSQHVEKLQDFQHLHPIVVQAAFPPLYKELFSTDIESSEGLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51450-1", "uniprot_id": "RORG_MOUSE", "id": "P51450-1", "name": "Nuclear receptor ROR-gamma", "aln": "------------------------------------------MDRAPQRHHRTSRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ--QQQQEQVAKTPPAGSRGADTLTYTLGLSDGQLPLGASPDLPEAS--ACPPGLLRASGSGPP-YSN-TLAKTEVQG---ASCHLEYSPERGKAEGRDSIYSTDGQLTLGRCGLRFEETRHPELGEPEQGPDSHCIPSFCSAPEVPYASLTDIEYLVQNVCKSFRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLTAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCS--ELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKT----HRQ-GLLAKLPPKG-KLRSLCSQHVEKLQIFQHLHPIVVQAAFPPLYKELFSTDVESPEGLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51449-1", "uniprot_id": "RORG_HUMAN", "id": "P51449-1", "name": "Nuclear receptor ROR-gamma", "aln": "------------------------------------------MDRAPQRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEAS--ACPPGLLKASGSGPS-YSN-NLAKAGLNG---ASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCS--ELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKT----HRQ-SILAKLPPKG-KLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HJG5-1", "uniprot_id": "A0AC58HJG5_DANRE", "id": "A0AC58HJG5-1", "name": "", "aln": "------------------------------------------MDHYYGGESDTG-YLAWRIKTIQAQIEVIPCKICGDKSSGVHYGVITCEGCKGFFRRSQSSSVQYSCSRQSNCPIDRASRNRCQSCRLKKCVAQGMSRDAVKFGRMSKRQRDSLFAEVERHRQH--QRLQANSVQEPQP------LQAYRSSKDTREQPSHLIPPLPAAYPFSVEPELAGCPAEVIP-YLDCHIVEAQTQG---LAYRVPLR--RGENNSLSAGRGFESTRSTPESILN------------MTGSEMGFHPFDPESSFFSYPTSLQTEELAASIIRSHKETTQYRLEELQALRWKVFSREEVHIYQSKPVDEMWQYCAVRLSDAVQYVVEFAKRIPGFRQLCQNDQIALLKSGSMEVVLVRMTRMFNTANNTVFFDGKYAGTELFKSLACS--DLIAAVFEFANNLCALRLNEQQMAVFTAMILINPDRPCLEDRERVQRVRTEVELALRHILHRD----NQE-SLLQKLYQRVPVLRSMCALHIEKLQWFRQLYPLTVHSLFPPLYKELFGSDADIHSLTTH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31396-1", "uniprot_id": "HR3_DROME", "id": "P31396-1", "name": "Probable nuclear hormone receptor HR3", "aln": "----------------------MYTQRMFDMWSSVTSKLEAHANNLGQSNVQSPAGQNNSSGSIKAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQ--------------------------------MRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGGYSNNE-----------VGYGSPYGYSASVTPQQTMQYDISADYVDST----------------TYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTN-TKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDSEEMRLVSRIFQTAKSIAELKLTETELALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPLKGDVTVLDTLLNNIPNFRDISILHMESLSKFKLQHPNVV---FPALYKELFSIDSQQDLT---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** ****:*******:****************** . *.*.*: .* :**..***** ***:**: **************:**:.: **. : : . . * . . : . . . : : .: .:. :* * : : ..: *: :* ** :::. :* ::**** : ** .*.*:*** **.:*.:*:.::** * : :.:* : . : * : .. :: *: .: : : :.* ::.:: : :*: ..* : .:::: *::: : : : * .* . . :. * * * *: :* * **.****** : ", "identical_positions": 115, "similar_positions": 112, "identity": "20.0%" }, { "cls_id": "homologset.agr.FB:FBgn0000455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0D7-1", "uniprot_id": "PEPD_RAT", "id": "Q5I0D7-1", "name": "Xaa-Pro dipeptidase", "aln": "MASTVRPSFSLGNETLKVPLALFALNRQR---------------------------------------------------LCERLRKN--GAVQAGSAVVLQGGEEMQRYCTDTSIIFRQESFFHWAFGVIESGCYGVIDVDTG----KSTLFVPRLPASYATWMGKIHSKEHFKEKYAVDDVQYADEIASVLTSRNPSVLLTLRGVNTDSGNVCREASFEGISKFTVNNTILHPEIVECRVFKTDMELEVLRYTNRISSEAHREVMKAVKVGMKEYEMESLFQHYCYSKGGMRHTSYTCICCSGENAAVLHYGHAGAPNDRTIKDGDICLFDMGGEYYCFASDITCSFPANGKFTDDQKAIYEAVLRSCRTVMSTMKPGVWWPDMHRLADRIHLEELTRIGLLSG--SVDAMLQVHLGAVFMPHGLGHFLGLDVHDVGGY-PEGVERIDEPGLRSLRTARHLEPGMVLTVEPGIYFIDHLLDQALAD-PAQACFFNQEVLQRFRNFGGVRIEEDVVVTDSGMELLTCVPRTVEEIEACMAGCDKALAP-SGPK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q11136-1", "uniprot_id": "PEPD_MOUSE", "id": "Q11136-1", "name": "Xaa-Pro dipeptidase", "aln": "MASTVRPSFSLGNETLKVPLALFALNRQR---------------------------------------------------LCERLRKN--GAVQAASAVVLQGGEEMQRYCTDTSIIFRQESFFHWAFGVVESGCYGVIDVDTG----KSTLFVPRLPDSYATWMGKIHSKEYFKEKYAVDDVQYTDEIASVLTSRNPSVLLTLRGVNTDSGSVCREASFEGISKFNVNNTILHPEIVECRVFKTDMELEVLRYTNRISSEAHREVMKAVKVGMKEYEMESLFQHYCYSRGGMRHTSYTCICCSGENAAVLHYGHAGAPNDRTIKDGDICLFDMGGEYYCFASDITCSFPANGKFTEDQKAIYEAVLRSCRTVMSTMKPGVWWPDMHRLADRIHLEELARIGLLSG--SVDAMLQVHLGAVFMPHGLGHFLGLDVHDVGGY-PEGVERIDEPGLRSLRTARHLEPGMVLTVEPGIYFIDHLLDQALAD-PAQACFFNQEVLQRFRNFGGVRIEEDVVVTDSGMELLTCVPRTVEEIEACMAGCDKASVPFSGQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12955-1", "uniprot_id": "PEPD_HUMAN", "id": "P12955-1", "name": "Xaa-Pro dipeptidase", "aln": "MAAATGPSFWLGNETLKVPLALFALNRQR---------------------------------------------------LCERLRKN--PAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTG----KSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSG--SVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGY-PEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALAD-PARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG79-1", "uniprot_id": "Q9VG79_DROME", "id": "Q9VG79-1", "name": "Xaa-Pro dipeptidase", "aln": "-----MAAFQMG-SGYAVPMTLFRNNRDRAGKA----------------------------------------------ILKELLPGL--KFNDGNLLVLLEGGKDQSLYNTDVDYVFRQESYFQYLFGVKEPGCYGILTIDVKTGAQKSVLFVPRFPDEYGTWMGELLGLQEFKAMYEVDEVFYVDEMSVYLEGASPKLILTLSGTNSDSGLTLQPPDFAGKEKYVTDCNLLYPILSECRVIKSPEEIEVLRYVAKVSSDAHIKVMRFMRPGRMEFEGESLFLHHAYSVGGCRHASYTCICGSGTNSSILHYGHAGAPNSKPVQDGDLCLFDMGANYCGYAADITCTFPANGKFTDDQKFIYNAVLDARNAVTESARDGVSWVDMHKLAGRVLLQRLKEGGMLKG--DVEEMLEAGVSGVFQPHGLGHLIGLDVHDVGGYLPKEPKRPSEPWLSKLRFARILKAGMYVTIEPGCYFINWLMDRALAD-PNIAKFINAEMFNRFRNFGGVRIEDDVLITKTGVENFAIVPRTVEDIEATMT-CKYDSPV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43590-1", "uniprot_id": "YFH6_YEAST", "id": "P43590-1", "name": "Uncharacterized peptidase YFR006W", "aln": "MCLEPISLVVFGSLVFFFGLVKYFKRGERQRTRGILQPEYKDKYYYSKEKGEEMGEVANVNEIPVKIRNHKYPAKEHNLRVKDLLLNRNPKLSKISTAFFIAGEELEGNKYCDTNKDFRQNRYFYHLSGVDIPASAILFNCSTD----KLTLFLPNIDEEDVIWSGMPLSLDEAMRVFDIDEALYISDLGKKFKELQDFAIFTTDLDNVHDENIAR--------SLIPSDPNFFYAMDETRAIKDWYEIESIRKACQISDKSHLAVMSALPIELNELQIQAEFEYHATRQGGR-SLGYDPICCSGPACGTLHY----VKNSEDIKGKHSILIDAGAEWRQYTSDITRCFPTSGKFTAEHREVYETVLDMQNQAMERIKPGAKWDDLHALTHKVLIKHFLSMGIFKKEFSEDEIFKRRASCAFYPHGLGHMLGLDVHDVGGN---PNYDDPDPMFRYLRIRRPLKENMVITNEPGCYFNQFLIKEFLEKHPERLEVVDMSVLKRYMYVGGVRIEDDILVTKDGYENLTGITSDPDEIEKIVQKGLKKPRSGFHVIV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* . :. : . :* : : * . ..: * : *.. ***: :* ** ... :: .. * .**:*.: . * * . : : :*:. * .::. : . ::* * .. : . . :. : * *.:* *:* :* . ::*..:* ** : * : :: * ::. ** .* ** ** .. *** . *.. ::. . *:* *.:: :::*** **:.**** ::: :*::** . . : *. * *:* *: :: ::.: *::. . : :.: . .* ******::*:******* :* : ** * *: .* :* *** ** : *:.. * . * ..: .:::*: .******:*:::*. * * :: :. ::** : ", "identical_positions": 108, "similar_positions": 152, "identity": "19.46%" }, { "cls_id": "homologset.agr.FB:FBgn0000459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUF8-1", "uniprot_id": "F1LUF8_RAT", "id": "F1LUF8-1", "name": "Zinc finger protein basonuclin-1", "aln": "--------------------------------------MRRSPSRGGRGAARAGYARREGRPRSG----------------------------------------RRMAEAIGCTLN-CSCQSFKPGKINHRQCEQCRHGWVAHALSKLRIPPVYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQEKEEQSIVIPPATANVDIRAFIESCG-HRSANLPTPVDKGNPSSMHPFENLISNMTFMLPFQFFNPLPPALIGSLPEQYVLEQGQDQSRDPKQDLHGPFSDSGFLTS--TPFQVEKEQCLSCPDAVT---QKEDSAHLSDSSSYSIASKLERTQLSPEAK--MKPERNSLSAKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSETYK--RPGFTVMSPDCGPLPGYTGSVEDSKGQPAFSSIGQNGVLFPNLKTVQPVLPFYRSPATPAELANTPGMLPSLPLISSS--------------IPEQLVSTDVP-FDALPKKKSRKSSMPIKIEKEAVEIADEK--RHSLSSDDDVPLQVVSED----EPEDSSP-----------QSDRVPEEQRTQLG-LEEPLPQGERACHLESVIEPHGAISRTLEQTTLT-ERESEQKVALSSVMPREVE-HDGHERHFTPGLGPQIPFPDYMELQQRLLAGGLFGALSNRGMAFP-FLEESKELGHLSEHALVRQKEETRFQCDICKKTFKNACSMKTHEKSTHARETHACTVDGCGAAFLSRRSRDRHSSNLSLHQKVLNEEALETSEDHFRAAYLLQDVAKEAYQDVAFTPQASQTSVIFKGTSGMGSLVYPISQVHSASLESYNSGPPSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTALMEDSDGNCE-GQSLVSAED-EYPICVLMEKADQSLASLPSGLP--ITCHLCQKIYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPGHLQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35914-1", "uniprot_id": "BNC1_MOUSE", "id": "O35914-1", "name": "Zinc finger protein basonuclin-1", "aln": "-----------------------------------------------------------------------------------------------------------MAEAIGCTLN-CSCQCFKPGKINHRQCEQCRHGWVAHALSKLRIPPVYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQEKEEQSVIVPPTTANVDIRAFIESCG-HRSASLPTPVDKGSPGGMHPFENLISNMTFMLPFQFFNPLPPALIGSLPEQYMLEQGQDQSQEPKQELHGPFSDSSFLTS--TPFQVEKEQCLNCPETVP---QKEDSAHLSDSSSYSIASKLERTQLSPEAK--VKPERNSLSAKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSETYK--RPGFTVVSPDCGPLPGYTGSVEDSKGQPAFSSIGQNGVLFPNLKTVQPVLPFYRSPATPAELANTPGMLPSLPLLSSS--------------IPEQLVSTDMP-FDALPKKKSRKSSMPIKIEKEAVEIAEEK--RHSLSSDDEVPLQVVSED----EPEDSSP-----------RSDRVPEEQHTQLS-LEEPLPQGERACHLESVIESHGALSRTLEQTTLT-EREAEQKVALSSVMPREVE-DGGHERHFTAGLVPQIPFPDYMELQQRLLAGGLFGALSNRGMAFP-FLEESKELEHLGEHALVRQKEEARFQCDICKKTFKNACSMKTHEKNTHARETHACTVEGCGAAFPSRRSRDRHSSNLSLHQKVLNEEALETSEDHFRAAYLLQDVAKEAYQDVAFTPQASQTSVIFKGTSGMGSLVYPISQVHSASLESYNSGPPSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTALMEDSDGNCE-GQSLVSGED-EYPLCVLMEKADQSLASLPSGLP--ITCHLCQKIYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPSHLQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01954-1", "uniprot_id": "BNC1_HUMAN", "id": "Q01954-1", "name": "Zinc finger protein basonuclin-1", "aln": "-------------------------------------MRRRPPSRGGRGAARARETRRQPRHRSG----------------------------------------RRMAEAISCTLN-CSCQSFKPGKINHRQCDQCKHGWVAHALSKLRIPPMYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQEKEEQSIIIPPSTANVDIRAFIESCS-HRSSSLPTPVDKGNPSSIHPFENLISNMTFMLPFQFFNPLPPALIGSLPEQYMLEQGHDQSQDPKQEVHGPFPDSSFLTSSSTPFQVEKDQCLNCPDAIT---KKEDSTHLSDSSSYNIVTKFERTQLSPEAK--VKPERNSLGTKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSENYK--CPGFTVTSPDCRPPPSYPGSGEDSKGQPAFPNIGQNGVLFPNLKTVQPVLPFYRSPATPAEVANTPGILPSLPLLSSS--------------IPEQLISNEMP-FDALPKKKSRKSSMPIKIEKEAVEIANEK--RHNLSSDEDMPLQVVSED----EQEACSP-----------QSHRVSEEQHVQSGGLGKPFPEGERPCHRESVIESSGAISQTPEQATHNSERETEQTPAL-IMVPREVE-DGGHEHYFTPGMEPQVPFSDYMELQQRLLAGGLFSALSNRGMAFP-CLEDSKELEHVGQHALARQIEENRFQCDICKKTFKNACSVKIHHKNMHVKEMHTCTVEGCNATFPSRRSRDRHSSNLNLHQKALSQEALESSEDHFRAAYLLKDVAKEAYQDVAFTQQASQTSVIFKGTSRMGSLVYPITQVHSASLESYNSGPLSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTVLMEDSDGNCE-GSSLVPGED-EYPICVLMEKADQSLASLPSGLP--ITCHLCQKTYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPSHLQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZN30-1", "uniprot_id": "BNC2_HUMAN", "id": "Q6ZN30-1", "name": "Zinc finger protein basonuclin-2", "aln": "MAHLGPTPPPHSLNYKSEDRLSEQDWPAYFKVPCCGVDTSQIESEEAEVDVRERETQRDREPKRARDLTLRDSCTDNSMQFGTRTTTAEPGFMGTWQNADTNLLFRMSQQAIRCTLVNCTCECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHPKSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGR-PPMGFTTPPLDPVLQNPLP----SQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPERDYENESES-SEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTDPTYDMFYMSQYGLYNGGGASMAALHESFTSSLNYGSPQKFSPEGDLCSSPDPK--ICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPS-LSKDLRDEFLVKIYGAQHPMGLDVREDASSPAG--------TEDSHLNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEG-ILLDDIDGASDSGESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIPFTSVD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23792-1", "uniprot_id": "DISC_DROME", "id": "P23792-1", "name": "Protein disconnected", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEHIMN--PFMSPAYLLG------------------------------HGPHSHQHVHSHLPSHPQPNAASPASSPGGSS----GSGSGSAAGSGTGSGSSLKPRRWGSPPIN--LAGQFINPATGKKRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSSRRSRNRHSANPNPKLHSPHIR--RKISPHDGRTAQQFPVFS--------------PGTAAAAAAVAGRLPVAFPG------------LLPPPPPHHG--HHPYVMFGGQAGLHGLGLLSTG------------------------------------------CQDPDSGSVDNEQ--DADPEDDNDFVYVDMQAN-------SSSP-----------AASSEDQEEHERDNEQDEEMHCSLSLASSSSIAADEERAADQPLDFSLHKRRKSEQDREQEQEQEQEREREAEKEQEQD--------------------------------------VESDKEHEPEQEHELERE-----------KRSPSDAFSMDQLLG-KRKRHDSTASSSACSTAAASSASSSSASASANPPQTSIKMDLDPDSDSAYMTS--------------------------------------------RRQMLPLPVLDLEEHHHLRLLQTQMFAAAAAAAATSQAPP------------TAFLPAGSPVDLAKDSPPMWSLLSEMYRSMLLKTQHQQY-----NHHHQLQQQHQQEQHHHLTLSHHHQEQHHHLGHHHMGHHHHHHHQHHQQQPQQQSPAATNAPISV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: . .*: * :. :. . .. : : : .. . . : . : : . . . .: * ** *. * *** ***:****:.****: *:**:********* ************:** * * *. . . . * . . . .:. : * *.: * : . * ::.:. : : . :* . .* :. : ** : . : : . . .* . : . : .: * . . :: :: .. : * . *:: ..: *:. : :. ..: .*.:: * * . *:. . :. :. : . . .: : .: * * *. : : :: :: :: . *.. .: .: * . : . : :: .:: : *: *: :. .: : * : * : :::* *: ::. . : ", "identical_positions": 80, "similar_positions": 166, "identity": "7.14%" }, { "cls_id": "homologset.agr.FB:FBgn0000463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97677-1", "uniprot_id": "DLL1_RAT", "id": "P97677-1", "name": "Delta-like protein 1", "aln": "MGRRS------ALALAVVSALLCQVWSSGVFELKLQEFVNKKGLLGNRNCCRG----GSGPP-CACRTFFRVCLKHYQASVSPEPPCTYGSAVTAVLGVDSFSLPDGA-GIDPAFSNPIRFPFGFTWPGTFSLIIEALHTDSPD--DLATENPERLISRLTTQRHLTVGEEWSQDLHSSGRTDLRYSYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKMCDPGWKGQYCTDPICLPGCDDQHGYCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCRNGATCTNTGQGSYTCSCRPGYTGANCELEVDECAP--SPCRNGGSCTDL---EDSYSCTCPPGFYGKVCELSAMTCADGPCFNGGRCSDN-----PDG-GYTCHCPAGFSGFNCEKKIDLCSSSPCSNGA-----------------------------------KCVDLGNSYLCRCQTGFSGRYCEDNVDDCASSPCANGGTCRDSVNDFSCTCPPGYTGRNCSAPVS--RCEHAPCHNGATCHQRGQ--RYMCECAQGYGGANCQFLLPEPPP--------DLIVA--AQGGSFPWVAVCAGVVLVLLLLLGCAAVVVCVRLKLQKHQPPPDP--CGGETETMNN---LAN-CQREKDVSVSIIGATQIKNTNKKADFHGDHG-----ADKSSFKARYPTVDYNLIRDLK------------GDEATVRD--AHSKRDTKCQSQGSVG--EEK-STSTLRGGEVPDRKRPES-----------------------------------VYSTSKDTKYQSVYVLSAEKDECVIATEV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61483-1", "uniprot_id": "DLL1_MOUSE", "id": "Q61483-1", "name": "Delta-like protein 1", "aln": "MGRRS------ALALAVVSALLCQVWSSGVFELKLQEFVNKKGLLGNRNCCRG----GSGPP-CACRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGA-GIDPAFSNPIRFPFGFTWPGTFSLIIEALHTDSPD--DLATENPERLISRLTTQRHLTVGEEWSQDLHSSGRTDLRYSYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGDRGEKMCDPGWKGQYCTDPICLPGCDDQHGYCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCRNGATCTNTGQGSYTCSCRPGYTGANCELEVDECAP--SPCKNGASCTDL---EDSFSCTCPPGFYGKVCELSAMTCADGPCFNGGRCSDN-----PDG-GYTCHCPLGFSGFNCEKKMDLCGSSPCSNGA-----------------------------------KCVDLGNSYLCRCQAGFSGRYCEDNVDDCASSPCANGGTCRDSVNDFSCTCPPGYTGKNCSAPVS--RCEHAPCHNGATCHQRGQ--RYMCECAQGYGGPNCQFLLPEPPPGPMVVDLSERHME--SQGGPFPWVAVCAGVVLVLLLLLGCAAVVVCVRLKLQKHQPPPEP--CGGETETMNN---LAN-CQREKDVSVSIIGATQIKNTNKKADFHGDHG-----AEKSSFKVRYPTVDYNLVRDLK------------GDEATVRD--THSKRDTKCQSQSSAG--EEK-IAPTLRGGEIPDRKRPES-----------------------------------VYSTSKDTKYQSVYVLSAEKDECVIATEV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00548-1", "uniprot_id": "DLL1_HUMAN", "id": "O00548-1", "name": "Delta-like protein 1", "aln": "MGSRC------ALALAVLSALLCQVWSSGVFELKLQEFVNKKGLLGNRNCCRG----GAGPPPCACRTFFRVCLKHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGG-GADSAFSNPIRFPFGFTWPGTFSLIIEALHTDSPD--DLATENPERLISRLATQRHLTVGEEWSQDLHSSGRTDLKYSYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP--SPCKNGGSCTDL---ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDS-----PDG-GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA-----------------------------------KCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVS--RCEHAPCHNGATCHERGH--RYVCECARGYGGPNCQFLLPELPPGPAVVDLTEKLE---GQGGPFPWVAVCAGVILVLMLLLGCAAVVVCVRLRLQKHRPPADP--CRGETETMNN---LAN-CQREKDISVSIIGATQIKNTNKKADFHGDHS-----ADKNGFKARYPAVDYNLVQDLK------------GDDTAVRD--AHSKRDTKCQPQGSSG--EEKGTPTTLRGGEASERKRPDS-----------------------------------GCSTSKDTKYQSVYVISEEKDECVIATEV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UWJ4-1", "uniprot_id": "DLLD_DANRE", "id": "Q8UWJ4-1", "name": "Delta-like protein D", "aln": "MGR--------LMIAVLLCVMISQGFCSGVFELKLQEFLNKKGVTGNANCCKGSA--AEG-HQCECKTFFRICLKHYQANVSPDPPCTYGGAVTPVLGSNSFQVPES--FPDSSFTNPIPFAFGFTWPGTFSLIIEALHTDSTD--DLSTENPDRLISRMTTQRHLTVGEEWSQDLQVGGRTELKYSYRFVCDEHYYGEGCSVFCRPRDDTFGHFTCGERGEIICNSGWKGQYCTEPICLPGCDEDHGFCDKPGECKCRVGFSGKYCDDCIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCQNGATCTNTGQGSYTCSCRPGFTGDSCEIEVNECSG--SPCRNGGSCTDL---ENTYSCTCPPGFYGRNCELSAMTCADGPCFNGGHCADN-----PEG-GYFCQCPMGYAGFNCEKKIDHCSSNPCSNDA-----------------------------------QCLDLVDSYLCQCPEGFTGTHCEDNIDECATYPCQNGGTCQDGLSDYTCTCPPGYTGKNCTSAVN--KCLHNPCHNGATCHEMDN--RYVCACIPGYGGRNCQFLLPENPQGQAIVEGADKRYSYEEDDGGFPWTAVCAGIILVLLVLIGGSVFVIYIRLKLQQRSQQIDS---HSEIETMNN---LTNNRSREKDLSVSIIGATQVKNINKKVDFQSDGD-------KNGFKSRYSLVDYNLVHELK--------QEDLGKED------SERSEATKCEPLDSDS---EEKHRNHLKSDSSERKR---------------------------------------TESLCKDTKYQSVFVLSEEKDECIIATEV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DI48-1", "uniprot_id": "DLLA_DANRE", "id": "Q6DI48-1", "name": "Delta-like protein A", "aln": "MGRHLL-----LLLFSILYMLLCQASSSGVFELKLQEFLNKKGVQGNKNCCKGGL--TTSYQQCECKTFFRICLKHYQPNASPEPPCTYGGTVTPVLGSNSFQVPDT--LPDGSFTNPIRMNFGFTWPGTFSLIIEALHADSKE--DLTTENPERIISTMTTQRHLTVGEDWSQDLHSVGRTELKYSYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEIICDAGWKGQYCTEPICLPGCDEEHGFCEKPGECKCRVGFKGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCLNGATCSNTGQGSYTCSCRPGFSGASCEIEVNECTG--NPCRNGGSCTDM---ENTYSCTCPPGFYGKNCELSAMTCADGPCFNGGRCADN-----PDG-GYFCQCPTGYAGFNCEKKIDHCSSSPCSNGA-----------------------------------RCVDLVNSYLCQCPDGFTGMNCDRAGDECSMYPCQNGGTCQEGASGYMCTCPPGYTGRNCSSPVS--RCQHNPCHNGATCHERNN--RYVCACVSGYGGRNCQFLLPDRASQIAS---------------DVPWTAVGSGVLLVLLLVVACAVVVVCVRSKVQQRRRDREDEVANGENETINN---LTNNCHRDKDLAVSVVGVAPVKNINKKIDFSSDHDDLSLTTEKRSYKTRHAPADYNLVHEVKFEVKHEVKLEHAGKETTMANELSDSCEDIKCQSLQDSSECTEEKRRKRLKSDASEKSKYSESRYSESKYSESKYSESKYSDVSLYSESACASACASASTSACVDTKYKSVMVMSEEKDECVIATEV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O57409-1", "uniprot_id": "DLLB_DANRE", "id": "O57409-1", "name": "Delta-like protein B", "aln": "MAHLS-------LYCLLSVSLLQLVASSGVFELKVHSFSTTR------RFCRR---------TRDCNIFFRICLKHSEDVISAEPPCTFGTGQTSVLRADQSSIASS---------AAIRVPFHFKWPGTFSLIIEAWNAESPKEHHDYTENQNNLISRLATRRRLAVGEDWSQDVHFGDQSELRYSYHVFCDEFYFGEACSDYCRPRDDTLGHYTCDENGNKECLVGWQGDYCSDPICSSDCSERHGYCESPGECKCRLGWQGPSCSECVHYPGCLHGTCSQPWQCVCKEGWGGLFCNQDLNYCTNHKPCANGATCTNTGQGSYTCTCRPGFGGTNCELEINECDC--NPCKNGGSCNDL---ENDYSCTCPQGFYGKNCEIIAMTCADDPCFNGGTCEEK-----FTG-GYVCRCPPTFTGSNCEKRLDRCSHKPCANGG-----------------------------------ECVDLGASALCRCRPGFSGSRCETNIDDCARYPCQNAGTCQDGINDYTCTCTLGFTGKNCSLRAD--ACLTNPCLHGGTCFTHFS--GPVCQCVPGFMGSTCEFPVQASLEKMAP-----------RVGQTSPSAVAVSCVLGVLAVFLGVCVGLVVLRRRRHRLRRQQLCDSVFNDLETVNN---------LDRQH--------------------------------YPYDRDFS-----------------------------------QVKPCNTEGRISLA---ASHT---LPAGQEFLWSAG-------------------------------------------GGLR-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9IAT6-1", "uniprot_id": "DLLC_DANRE", "id": "Q9IAT6-1", "name": "Delta-like protein C", "aln": "MARVL-------LTCFFILISSHLGKSSGVFELKVLSFTSTS------SVCKG---------SSDCQIFFRVCLKHSQALILPEPPCTYGTGMSEILSAD--SISSS---------AYISVPFNFKWPGIVSLIIETWNAETS---DQSTENNNNMISRLATKRRLAISEDWSQDVHLGRQSQLRFSYRVVCDEFYHGEECSDFCRPRNDTFGHFNCDAAGNRICLPGWKGDYCTEPICLSGCSEENGYCEAPGECKCRIGWEGPLCDECTRHPGCLHGTCNQPFQCTCKEGWGGLFCNEDLNFCTNHKPCRNDATCTNTGQGSYTCICKPGFSGKNCEIETNECDS--NPCKNGGSCNDQ---ENDYTCTCPQGFYGKNCEVSAMTCADGPCFNGGTCMEK-----GSG-SYSCRCPPGYMGSNCEKKIDRCSSDPCANGG-----------------------------------QCLDLGNKATCRCRPGFTGSRCETNIDDCSSNPCQNAGTCVDGINGYTCTCTLGFSGKDCRVRSD--ACSFMPCQNGGTCYTHFS--GPVCQCPAGFMGTQCEY-----KQKPTP-----------VNSPALPAALIVSFTLGLITLTLVICAAIVVLRQMRQNHKAS--STTVRNNLDSVNNRISLSPTSPLGREKEAFLIPGGPFKVSNKDMALRSTSV--------DTHSSDKS-----------------------------------NYKQKMVDYNLSID---EKHTNNKLEKNSESTLLVPPL-------------------------------------NYPKEGVYHPVYIIPEHIEQRVFATEV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZHH1-1", "uniprot_id": "DLL4_RAT", "id": "D3ZHH1-1", "name": "Delta-like protein 4", "aln": "MTPGSRSACRWALLLLAVLWPQQRAAGSGIFQLRLQEFANERGMLANGRPCEP-----------GCRTFFRICLKHYQATFS-EGPCTFGNVSTPVLGTNSFVIRDK---NSGSGRNPLQLPFNFTWPGTFSLNIQAWHTPGDD-LRPETSPGNSLISQIIIQGSLAVGKNWKSDEQNNTLTRLRYSYRVVCSDNYYGDSCSRLCKKRDDHFGHYECQPDGSLSCLPGWTGKYCDQPICLSGCHEQNGYCSKPDECNCRPGWQGPLCNECIPHNGCRHGTCTIPWQCACDEGWGGLFCDQDLNYCTHHSPCKNGSTCSNSGPRGYTCTCLPGYTGEHCELELSKCAS--NPCRNGGSCKDH---ENSYHCLCPPGYYGQHCEHSTLTCADSPCFNGGSCRER-----NQGASYACECPPNFTGSNCEKKVDRCTSNPCANGG-----------------------------------QCLNRGPSRTCRCRPGFTGTHCELHISDCARSPCAHGGTCHDLENGPVCTCPAGFSGRRCEVRITNDACASGPCFNGATCYTGLSPNNFVCNCPYGFVGSRCEFPVGLPPS--------------------FPWVAVSLGVGLVVLLVLLVMVAVAVRQLRLRRPDDD--------SREAMNN---------LSDFQKDNLIPAAQLKNTNQKKELEVDCG----LDKSNCGKLQNHTLDYNLAPGFLG---------------------RGSTPGKYPHSDKSLG----EKVPLRLHSEKPACRISAICS--------------------------------------PRDSMYQSVCLISEERNECVIATEV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI71-1", "uniprot_id": "DLL4_MOUSE", "id": "Q9JI71-1", "name": "Delta-like protein 4", "aln": "MTPASRSACRWALLLLAVLWPQQRAAGSGIFQLRLQEFVNQRGMLANGQSCEP-----------GCRTFFRICLKHFQATFS-EGPCTFGNVSTPVLGTNSFVVRDK---NSGSGRNPLQLPFNFTWPGTFSLNIQAWHTPGDD-LRPETSPGNSLISQIIIQGSLAVGKIWRTDEQNDTLTRLSYSYRVICSDNYYGESCSRLCKKRDDHFGHYECQPDGSLSCLPGWTGKYCDQPICLSGCHEQNGYCSKPDECICRPGWQGRLCNECIPHNGCRHGTCSIPWQCACDEGWGGLFCDQDLNYCTHHSPCKNGSTCSNSGPKGYTCTCLPGYTGEHCELGLSKCAS--NPCRNGGSCKDQ---ENSYHCLCPPGYYGQHCEHSTLTCADSPCFNGGSCRER-----NQGSSYACECPPNFTGSNCEKKVDRCTSNPCANGG-----------------------------------QCQNRGPSRTCRCRPGFTGTHCELHISDCARSPCAHGGTCHDLENGPVCTCPAGFSGRRCEVRITHDACASGPCFNGATCYTGLSPNNFVCNCPYGFVGSRCEFPVGLPPS--------------------FPWVAVSLGVGLVVLLVLLVMVVVAVRQLRLRRPDDE--------SREAMNN---------LSDFQKDNLIPAAQLKNTNQKKELEVDCG----LDKSNCGKLQNHTLDYNLAPGLLG---------------------RGGMPGKYPHSDKSLG----EKVPLRLHSEKPECRISAICS--------------------------------------PRDSMYQSVCLISEERNECVIATEV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR61-1", "uniprot_id": "DLL4_HUMAN", "id": "Q9NR61-1", "name": "Delta-like protein 4", "aln": "MAAASRSASGWALLLLVALW-QQRAAGSGVFQLQLQEFINERGVLASGRPCEP-----------GCRTFFRVCLKHFQAVVS-PGPCTFGTVSTPVLGTNSFAVRDD---SSGGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDD-LRPEALPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDS--NPCRNGGSCKDQ---EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRER-----NQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG-----------------------------------QCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPPS--------------------FPWVAVSLGVGLAVLLVLLGMVAVAVRQLRLRRPDDG--------SREAMNN---------LSDFQKDNLIPAAQLKNTNQKKELEVDCG----LDKSNCGKQQNHTLDYNLAPGPLG---------------------RGTMPGKFPHSDKSLG----EKAPLRLHSEKPECRISAICS--------------------------------------PRDSMYQSVCLISEERNECVIATEV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10041-1", "uniprot_id": "DL_DROME", "id": "P10041-1", "name": "Neurogenic locus protein delta", "aln": "MHWIK-----CLLTAFICFTVIVQVHSSGSFELRLKYFSNDHGRDNEGRCCSGESDGATGKCLGSCKTRFRVCLKHYQATIDTTSQCTYGDVITPILGENSVNLTDAQRFQNKGFTNPIQFPFSFSWPGTFSLIVEAWHDTNNS---GNARTNKLLIQRLLVQQVLEVSSEWKTNKSESQYTSLEYDFRVTCDLNYYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIPKCAKGC--EHGHCDKPNQCVCQLGWKGALCNECVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNHRPCKNGGTCFNTGEGLYTCKCAPGYSGDDCENEIYSCDADVNPCQNGGTCIDEPHTKTGYKCHCANGWSGKMCEEKVLTCSDKPCHQG-ICRNVRPGLGSKGQGYQCECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGKCICPAGFSGTRCETNIDDCLGHQCENGGTCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGKDCSVDID--ECSSGPCHNGGTCMNRVN--SFECVCANGFRGKQCDEESYDSVTFDAHQYGATTQARADGLTNAQVVLIAVFSVAMPLVAVIAACVVFCMKRKRKRAQEKDDAEARKQNEQNAVAT------MHHNGSGVGVALASASLGGKTGSNSGLTFDGGNP--NIIKNTWDKSVNNICASAAAAAAA-------AAAADECLMYGGYVASVADNNNANSDFCVAPLQRAKSQKQLNTDPTLMHRGSPAGSSAKGASGGGPGAAEGKRISVLGEGSYCSQRWPSLAAAGVAGACSSQLMAAASVAGSGAGTAQQQRSVVCGTPHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ** *:*:: * . * *. **:**** : **:* : :* : : . : . * *.*** .** ::: : : . :*. : : * :.. * : : * :.::. *. *.*. *: *: *:* :** * *. * ** * ** * * .* :*.*. * :* *: *:.* *.:* .* **** *: * *.******:*::***:**:* ** *..** *:* *** * **: * ** .* .**:**.:* * : : * *. *: * ** .::*:* **.:* * : * .* *.** : * **: ::* * .** *.. * : *:* ** * *. . * ** :.*** : .. *** *::*: * * ** : .** * * *: * *: : : . . : : . ::: . . . * ", "identical_positions": 157, "similar_positions": 122, "identity": "18.19%" }, { "cls_id": "homologset.agr.FB:FBgn0000464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64487-4", "uniprot_id": "PTPRD_MOUSE", "id": "Q64487-4", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "---------M--VPVARPLSLLLTFFLC-ACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGE-ISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPP-TNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIASYELVYRDGD-QGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMN---TALIQWHPPVDTFGP--LQGYRLKFGRKD--MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTST-SVQLSWQPPVLA-------------------ERNGVITKYTLLYRDINVPLLPMEHLIVPA-----DTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD-QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKL-------IVNLKPEKSYSFVLTNRGNS-AGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-------------------------------------------------------------------------------GMITVQLPDVPANENIK-GYY--------IIIVPLKKSRGK-FIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVELK-PYIAAHF--DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAE-------SKMYATSPYSDPVVSMDLDP--------------------QPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKR------KRAESES-RKSSLPNSKEVPSHHPTDPVELRRLNFQTPG----------------MASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRK--QNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRV--------KCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LD14-1", "uniprot_id": "A0ABK0LD14_RAT", "id": "A0ABK0LD14-1", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "--MPLTSCRM--VPVARLLLLLLAFFLY-ACAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGE-ISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS---GGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRG-RNVRRVPPRFSIPP-TNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIASYELVYRDGD-QGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDYRPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDATEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGRPRLVINHTQMN---TALIQWHPPVDTFGP--LQGYRLKFGRKD--MEPLTTLEFSEKEDHFTATDIHKGASYIFRLSARNKVGFGEEMVKEISVPEEVPTGFPQNLHSEGTTST-SVQISWQPPVLA-------------------ERNGVITKYTLLYRDINVPLLPMEHLIVPA-----DTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD-QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKL-------IVNLKPEKSYSFVLTNRGNS-AGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-------------------------------------------------------------------------------GMITVQLPDVPANENIK-GYY--------IIIVPLKKSRGK-FIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVELK-PYIAAHF--DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMDHAE-------SKMYATSPYSDPVVSMDLDP--------------------QPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKR------KRAESES-RKSSLPNSKEVPSHHPTDPVELRRLNFQTPGSDDSG--YPGNLHFSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRK--QNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRV--------KCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23468-1", "uniprot_id": "PTPRD_HUMAN", "id": "P23468-1", "name": "Receptor-type tyrosine-protein phosphatase delta", "aln": "---------M--VHVARLLLLLLTFFLR-TDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGE-ISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPP-TNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIANYELVYKDGE-HGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMN---TALIQWHPPVDTFGP--LQGYRLKFGRKD--MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTST-SVQLSWQPPVLA-------------------ERNGIITKYTLLYRDINIPLLPMEQLIVPA-----DTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVD-QVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKL-------IVNLKPEKSYSFVLTNRGNS-AGGLQHRVTAKTAPDVLRTKPAFIGKTNLD-------------------------------------------------------------------------------GMITVQLPEVPANENIK-GYY--------IIIVPLKKSRGK-FIKPWESPDEMELDELLKE--ISRK-RRSIRYGREVELK-PYIAAHF--DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAE-------SKMYATSPYSDPVVSMDLDP--------------------QPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKR------KRAESDS-RKSSIPNNKEIPSHHPTDPVELRRLNFQTPG----------------MASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRK--QNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRV--------KCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V2N1-1", "uniprot_id": "PTPRS_MOUSE", "id": "B0V2N1-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "-MAPTWSPSV--VSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN--SQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGE-ITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILP-MSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ---ESVIKYELLFREGD-RGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ---------EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEG---SLLARWEPPADAAED-PVLGYRLQFGRED--AAP-ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQILGAAGNVSAGSVLLRWLPPVPA-------------------ERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARD-PVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYN--GLTLDVDGRTTKKL-------ITHLKPHTFYNFVLTNRGSS-LGGLQQTVTARTAFNMLSGKPSVAPKPDND-------------------------------------------------------------------------------GFIVVYLPDGQSPVTVQ-NYF--------IVMVPLRKSRGGQFPVLLGSPEDMDLEELIQD--ISRLQRRSLRHSRQLEVPRPYIAARF--SILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKN--------EPTFAASPFSDPFQLDNPDP--------------------QPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKN-KPDS-KRKDSEP-RTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRR--QNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRI--------KCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64605-1", "uniprot_id": "PTPRS_RAT", "id": "Q64605-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "-MAPTWRPSV--VSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN--SQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGE-ITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILP-MSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ---ESVIKYELLFREGD-RGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ---------EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEG---SLLARWEPPADAAED-PVLGYRLQFGRED--AAP-ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEEASAALSIPEDAPRGFPQILGAAGNVSAGSVILRWLPPVPA-------------------ERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARD-PVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYN--GLTLDVDGRTTKKL-------ITHLKPHTFYNFVLTNRGSS-LGGLQQTVTARTAFNMLSGKPSVAPKPDND-------------------------------------------------------------------------------GSIVVYLPDGQSPVTVQ-NYF--------IVMVPLRKSRGGQFPILLGSPEDMDLEELIQD--LSRLQRRSLRHSRQLEVPRPYIAARF--SILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKN--------EPTFAASPFSDPFQLDNPDP--------------------QPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKN-KPDS-KRKDSEP-RTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRR--QNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRV--------KCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13332-1", "uniprot_id": "PTPRS_HUMAN", "id": "Q13332-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "-MAPTWGPGM--VSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN--SQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGE-ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILP-MSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ---ESIIKYELLFREGD-HGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEG---SLLARWEPPAGTAED-QVLGYRLQFGRED--STPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPA-------------------ERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRD-QVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYN--GLTLDVDGRTTKKL-------ITHLKPHTFYNFVLTNRGSS-LGGLQQTVTAWTAFNLLNGKPSVAPKPDAD-------------------------------------------------------------------------------GFIMVYLPDGQSPVPVQ-SYF--------IVMVPLRKSRGGQFLTPLGSPEDMDLEELIQD--ISRLQRRSLRHSRQLEVPRPYIAARF--SVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKS--------EPTFAASPFSDPFQLDNPDP--------------------QPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKN-KPDS-KRKDSEP-RTKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRC--QNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRI--------KCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAP8-1", "uniprot_id": "A0AB32TAP8_DANRE", "id": "A0AB32TAP8-1", "name": "protein-tyrosine-phosphatase", "aln": "-MMPTGHLPI--LLSLS--ALLLSPLLTGSLALSSPRFTKVPVDMIGVSGGVVSFVCQATGDPKPKVTWNKKGKRVN--SQRIETIEFDEGAGAVLRIQPLRAPRDENVYECQAENSEGE-INVQAKLSIIREDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPIDPNTSNGRIKQLR---------SGALQIENTEETDQGKYECVASNVEGVRYSSPANLYVRELREVRRVPPRFSILP-TSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEMPVGRNVLELNSVRESANYTCVAMSSLGIIETVAQITVKSLPKPPGTPVVTETTATSITITWDSGNPEPVSHYIIQYRAKSPESKFETVDSITTTRYSIGGLSPNTDYEIRVSAFNTIGQGPPSEPVEARTGEQAPASPPRNIQARIISQNTVLVRWDEPDEPNGQIKGYRVYYTMDPTLPMSMWQIHNVQDSVLTTIQSLVTSETYTIRVLAFTSVGDGPFSDPIHVKVLQGVPGQPTNFQVGEVSDTGVELTWEPAFEK--EGIISYELHYKEGK-DGPLGKKKFAPTSSFVVDGLRPNTEYFFSLAAVSSKGIGAFTNDLAQTTSQAKPSAPPQDIKCSSSSSTVLMVSWRPPPAESQNGELAGYIVRYAVVGAG-AEVSTEHVEAPTSDQILLQRLEKWTMYRVTVAASTSVGSGPESEPLLCRTDEDVPGAPPRRVEVEVLNSTAIKVMWRSLLPGKQHGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQWEMDDTAEYEMVIGGLQPDTTYSITVAAYTTKGDGARSKPKLVLTKGAVPGPPFLSVNQNSES---TAIIRWQPPDYVAPGLEVQGYRLQFGRKD--VNPLATLEFGPQELEYSISNIHRGATYIFKVSAKSKSGFGEEATQELRVPEEVPRGYPQITEGS-NITCCSVQFSWLPPVLA-------------------ERNGAITEYTLSYQEAGTISGPKELRLPAD-----ENSYILNSLRPNAVYDVKIRAHTSVGPGPYSPPIQYRTVAYE-ADVPRNFTVKLVTKTTVLLSWKFYDSR-FPYKCTIEYH--RQKSDIDARMTKTL-------ITNLRPNTTYEFRISCQDSS-DGGPKHKLVARTAPHIQIRKPELDLKRESE-------------------------------------------------------------------------------STLTIVFPPLETKDLIK-AIY--------VVVVPLKKGKGP--MRHIKSPDELDLEELLGERRLGLHHSGTTRQLKQVDGKRPYIAASFKPSSMPPSFTLGNQMMYGSFENRALDRGQEYVLFILAELNTTG-------VKAFVSSPYTDPIMAPDLDP--------------------QPLESGGDGLIWVVGPVLAVVFIICIVIAILLYKNSKPDSSKRKESEP-RTKCLLNNADITPHHPTDPVEMRRINFQTPDSGLSSPVSEAGFDYESMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINSNYIDGYRK--QNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTRLEEKSRI--------KCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLFSYIQKLAQVEAGEHVSGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2A8L5-1", "uniprot_id": "PTPRF_MOUSE", "id": "A2A8L5-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-MAPEPAPGR--RMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGE-INTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPP-SSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLPPQ---ERIVKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ---------ETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMH---TALLQWHPPKELPGE--LLGYRLQYRRAD--EARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQNLRVTGLTTS-TTELTWDPPVLA-------------------ERNGHITNYTVVYRDINSQ---LELQNVTN-----DTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVE-QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN--GQSVEVDGHSMRKL-------IADLQPNTEYSFVLMNRGSS-AGGLQHLVSIRTAPDLLPQKPLPASAFIED-------------------------------------------------------------------------------GRFSLSMPQVQDPSLVR-WFY--------IVVVPIDRVGGNLLAPRWNTPEELELDELLEA--IEQGEEKQRRRRRQAERLKPYVAAQV--DVLPDTFTLGDKKSYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPA--------------------QQQ--EEPEMLWVTGPVLAVILIILIVIAILLFKR------KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRK--QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRV--------KCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLANSKAHTSRFVSANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64604-1", "uniprot_id": "PTPRF_RAT", "id": "Q64604-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-MAPEPAPGR--RMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQIGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGE-INTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPP-SSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQ---ERIIKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ---------ETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMH---TALLQWHPPKELPGE--LLGYRLQYRRAD--EARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTS-TTELAWDPPVLA-------------------ERNGRITNYTVVYRDINSQ---HELQNVTG-----DVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPME-QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN--GQSVEVDGHSMRKL-------IADLQPNTEYSFVLMNRGTS-AGGLQHLVSIRTAPDLLPQKPLPASAFIED-------------------------------------------------------------------------------GRFSLSMPQVQDPSLVR-WFY--------IVVVPIDRVGGNLLAPRWSTPEELELDELLEA--IEQGEEKQRRRRRQAERLKPYVAAQV--DELPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPA--------------------QQQ--EEPEMLWVTGPVLAVILIILIVIAILLFKR------KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRK--QNAYIATQGPLPETMGDFWRMVWEQRIATVVMMTRLEEKSRV--------KCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLAGSKARASRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10586-1", "uniprot_id": "PTPRF_HUMAN", "id": "P10586-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-MAPEPAPGR--TMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGE-INTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG---------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSIPP-SSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQ---ERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMN---TALLQWHPPKELPGE--LLGYRLQYCRAD--EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTS-TTELAWDPPVLA-------------------ERNGRIISYTVVFRDINSQ---QELQNITT-----DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVE-QVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN--GQSVEVDGHSMRKL-------IADLQPNTEYSFVLMNRGSS-AGGLQHLVSIRTAPDLLPHKPLPASAYIED-------------------------------------------------------------------------------GRFDLSMPHVQDPSLVR-WFY--------IVVVPIDRVGGSMLTPRWSTPEELELDELLEA--IEQGGEEQRRRRRQAERLKPYVAAQL--DVLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEP------MDQKRYASSPYSDEIVVQVTPA--------------------QQQ--EEPEMLWVTGPVLAVILIILIVIAILLFKR------KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG----------------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRK--QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRV--------KCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IFW2-1", "uniprot_id": "PTPRF_DANRE", "id": "A4IFW2-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-MVPNTCTSVPLLPVGLPLLLLLSCIQFSSQADSLPNFVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVS--SQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSLGE-INTSAKLTVLEENQIPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDING-NGRIKQLRSG---------ALQIENSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVPPRFSIPP-TNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQ---DPIIKYELQYWEADSDNK-IHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTVGN---TALIQWQPPKDMVGE--LMGYRLRYKRLE--EENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTS-TTRLTWEPPALS-------------------ERNGRIIHYIVVYRDINSK---QNSTNRTS-----DTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTS-PAFATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN--QQSVEVQGNLKRKL-------ITRLQPDTDYSFVLMSRGNS-AGGLQQQVSIRTAPDLFKTKPVLYTADQTNN------------------------------------------------------------------------------GKLTINLPKVPTSAPVR-CYY--------IVVVPVSQTS----SRQWINPDEMELDELLES--SE-GAHLRRRRRHT-DTVRPYIAAKL--STLPETFTLGDELDYSGFINRPLPNNQHFQCFVMAELKDQYPVTANEKQRTFSASPYSDPIIVQGENQ--------------------MQRSVDQPEMLWVMGPVLAVVLIIIIVIAILLFKR------KR-ASPLPKDDHSGGVKDCLLASSSDPVEMRRLNYQTPG----------------MREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRK--QNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRV--------KCDQYWPIRGTETYGMIQVTMLDAVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQPSAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------LFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TXQ6-1", "uniprot_id": "A0AB32TXQ6_DANRE", "id": "A0AB32TXQ6-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "-MVPQTRQGS--ARHGATSLLLLLCLAVPIHADSMPSFVKTPEDQTGISGGVASFVCQAVGEPKPRITWMKKGKKVS--SQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGE-INTSAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGG---TPIRGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVR----VRRVPPRFSIPP-TNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGMIDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSYYVIQYRSKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQ---DQITKYELTYWEADSDNK-HHVIFDPAGSYAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQ---------EAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTIGN---TALIQWQPPKEMVGE--LMGYRLRYKREE--EDIYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLKVVGLTTT-TTKLAWDPPPLP-------------------ERNGKIVRYVVVYRDINSH---QNQTNGTA-----DTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSMPEFTKNFGVKAVMKTSVLLTWEVPETYKSQVPFKILYN--QQSVEVQGDLKRKL-------ITRLQPDTDYSFVLMSRGNS-AGGLQQQVSIRTAPDLFTTKPAHQKLDPEEG------------------------------------------------------------------------------GKLAITLPEVHNSALVR-WFY--------IVVVPVTPST----LRHWENPEDIDLDELMGN--NR-DAAVRRRRRQTQDFLRPYIAAKL--ESLPERFVLGDEKTYSNYYNKPLPGQQQYRTFILAALKD--------RDSTFTVSPFSEPMMVKLHSG--------------------MSRHVEDPEMLWVMGPVLAVVLIIIIVIAILLFKR------KR-TSPSAKDEHSAGVKDHLLAHSSDPVEMRRLNYQTQGSSAFN-----CPSTSRMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRK--QNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRV--------KCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQAPPGDTVTAMELEFKKLANSKAHTSRFISASLPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------MFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q0T4-1", "uniprot_id": "A0A8M9Q0T4_DANRE", "id": "A0A8M9Q0T4-1", "name": "protein-tyrosine-phosphatase", "aln": "-MARGHMIYR---SAYQPLLLILLSALQLAHMQSAPRFTRTPTDQIGVQGGVASFVCQATGDPQPKITWSRKGKKVT--NQRFEVIEFEDGSGSALRVQPLRTPRDEAIYECVASNEIGE-ITASTRLSVLREDQLPAGFPSIDMGPQLKVVERSRTATMLCAASGTPDPEITWFKDFLPIDTHT-HGRIKQLRSGG---TPIRGALQIDQSEETDQGKYECVATNSEGTRYSTPANLYVRELRDVRRIPPRFSVPP-MDYEIMPGGSVNITCQAVGVPMPYVKWMLGAEDLTPEDDMPIGRNVLELTNVRQSANYTCVAMSTLGVIETVSQITVKALPNPPGSPVVMERSATSITLMWDSGNPHPVSYYIIQYRPSSSTDPFKEIDAIATTRYSVGGLSPYSHYHFRVVAVNSIGRGAPSPTVDARTAEQAPSSPPRRVRGRMLSGSTAMVQWEEPEEANGQVVGYRVYYTSDSSLSVSQWEKEMVRGANFLNIRDLTPNKTYYIRVLAFTAVGDGPLSSDLHIIAKTGVPSQPTELKAEVKSETSILLSWIPPAHSGTDAITGYELIYRLGD--QPEQKITFDPSSSYLLKNLKPFSTYVFQLAARSKHGLGAFTSEITVQTPQTQSIPPPQDVTCTSPSSTSLLLSWASPPTD-ENGIVTGYSIRYVAVERDKDPVQKISDIPSNCFRYRIEGLKKGTLYSVTIAAHTDNGQGPESLPILVRTEEDVPSAPPRGVDVVVLNATSARVSWKPPVAERQHGKIRGFQVTYARRTAGERTVSPRIREHLLRDPQQPQNDSIEHEVILTDLWPNTEYSVTVAAFTSKGDGARSKPIVIRTKPSLPGMPLLTVVSSEDS---TALLKWQPPPTGLSP--VLGYRLSYGQADPSSDTFMVQELGAEERSYTVSSLSAGVLYVFRLAARTVWGYGSSAQVTLLIPNVVQTTTDGMITDLMTTEGQTMSVQENVPILANLTAESINSSSAILRWERPKNYDGIQGYRVWFAVTYSNGTDIAMESDVS-----ETTVVLHGLRANTEYVARVCMLSKQGPGPYSLPISIKTQPAE-EVFAVNFKVKAAMKSSVLLTWESRTTSNKAQSLIISYGD-GESVEVDGRLGQKL-------VTKLKPQSLYNFLLTSKSDS-TGGLQHRTDAMTAPNLMTRKPQLLDKTSSQ-------------------------------------------------------------------------------SIAILQLPTVQGQANVR-GFY--------ILVVPLKRQRAGNFQNMWSDPDEMNLDELLRE---INGTGRSVRLRRQAEAK-PYITAHF--QNLPAEFKLGDGHVYGAFMNRPLVNGQEYVCFVLAILELG-------QNTVYSTSPFSDAVLFSDVEP--------------------QPIVDEEEGLLWVVGPVLAVIFIISIVILILLFKS--KPDRKRAELEGRKCSFLSSGKAMSSQHPSDPVELRRINFPTAG----------------MTSHPPVSVSELPAHIERMKANDSLRFSQEYESIDPGQQFSWEHSNLEINKPKNRYANVIAYDHTRVALTNTDGVAGGDYINANFIDGYRR--QGAYIATQGPMPDTFSDFWRMVWEQHTANVIMITKLEEKSRMPSYFFSKNKCDQYWPSRGTETYGLMQVSLLDTVELATYCVRTFALFKSGSGEKREVRQFQFTAWPDQGVPEHPTPFLAFLRRVKACNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERVKQEKTLDIYGHVTLMRSQRNYMVQTEEQYVFIYEALLEAVSCGNTEVPARNLYAYIQRLSQTEPPEHISGMEQEFKRLANAKAHNSRFVSASLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYVNGSFIDGYRQQRAYIATQGPLAETVEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPSDRSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD------------IFQTVKMLRTQRPAMVQTEEQYQFCYRAGLEYLGSFDHYAT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16621-1", "uniprot_id": "LAR_DROME", "id": "P16621-1", "name": "Tyrosine-protein phosphatase Lar", "aln": "MGLQMTAARPIAALSLLVLSLLTWTHPTIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQ-PGGISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDGF------------LQIENSREEDQGKYECVAENSMGTEHSKATNLYVK----VRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHS-SENIVHYELYWNDTY-ANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMT---LNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDP-QDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTL---------EFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGE--LRGYRLRWGVKD--QALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPD-VLCVTWDPPTRE-------------------HRNGIITRYDVQFHKKIDHGLGSERNMTLR-------KAVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDM-GRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYT-MTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLGRLSEKVTVRIKPEDVPLNLRAHDVSTHSMTLSWSPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYVKTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFPQRSIPFTFHLGSGDDYHNFTNRKLEREKRYRIFVRAVVDTP-------QKHLYTSSPFSEFLSLDMREAPPGERPHRPDPNWPAEPEVSVNRNKDEPEILWVVLPLMVSTFIVSTALIVLCVVK-RRRQPCKTPDQAAVTRPLMAADLGAGPTPSDPVDMRRLNFQTPG----------------MISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRK--HNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRI--------KCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLD------------VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYTN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29461-1", "uniprot_id": "PTP2_YEAST", "id": "P29461-1", "name": "Tyrosine-protein phosphatase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRIAQQYRNGKRDNNGNRMASSAISEKGHIQVN----QTRTPGQMPVYR--------GETINLSNLPQNQ----IKPCKDLDDVNIRRNNSNRHSKILLLDLCAGPNTNSFLGNTN-----AKDITVLSLPLP-------------------------------------------------------STLVKRSNYPFENLLKNYLGSD------------------------------------EKYIEFTKIIKDYDIFIFSDSFSRISSCLKT-----------------TFCLIEKFKKFICHFFPSPYLKFFLLEGSLNDSKAPSLGKNKKNCILPKLDLNLN---------------------------------------------VNLTSRSTLNLRINIPPPNDSNKIFLQSLKKDLIHYSPNSLQKFFQFNMPADLAPNDTILPNWLKFCSVKENEKVILKKLFNNFETLENFEMQRLEKCLKFKKKPLHQKQLSQKQR--------------GPQSTDDSKLYSLTSLQRQYKSSLKS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIQKNQKLKLIIPKNNTS-----------------------------------------------------------------------------------------------------------------SSPSPLSSDDTIMS---------------------------------------------------------------------------------------------------------------------------------PINDYELTEGIQS---------------------------------------------------FTKN--------------RYSNILPYEHSRVKLPHSP-------------------------------KPPAVSEASTTETKTDKSYPMCPVDAKNHSCKP-----------------------------------------NDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLR--------KWDIYWNN-------------------LSYSNHTIKLQN--------------------------------------------------------------------------------------------------------------------------------------TWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVS-----------------EPFIVYQLQYKNWLDSCG---VDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTAN----------------------------------------------------------------SSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYFALQKQIKNALPC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :** : . . . * :: *. * . :. * .:*:: . . :* . ::. : . :. : * .: . * ... .: :.* :** . * :.* : * :* . . . : .* :: : : : . : * ::. * :. .. : . *:: * . . : . . .. . : : : *:: : .. . . * . . *: : :: :. . : . . : * .: . .* :** . . : :: .. : .* .* .**:*.*: . : . *:***..: .*: ***:: : :: :. :* . * * ** :: :*: * . . : : :: . : * .: . . *: :* : :. : . : :: : * :*: : :** :. : : .: :: * :.. . : ..: ..*: ****** **:***:**.::*. : . :* :. **.** :***. :* .:.* *:*:. .: . ", "identical_positions": 85, "similar_positions": 211, "identity": "3.96%" }, { "cls_id": "homologset.agr.FB:FBgn0000477", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZK9-1", "uniprot_id": "DNS2B_RAT", "id": "Q9QZK9-1", "name": "Deoxyribonuclease-2-beta", "aln": "----MTAQPLKAALPLLFVALSGVLGTPVISCINEDGKAVDWFAFYKLPR---RTSRGGTGMGLDYLYLDST-MRTWSKSHHLINSSRSSLGRTLEQLYEAHNAK-NDTAYLIYNDAVPAS--VNYSGNYGHAKGLLVWNRVQGFWLIHSIPKFP-PVPEKGYEYPSSGRQYAQSGLCITLKYSQYETIDSQLLVFQPNIYS--CFIPNIFRWELIHMPQMCAKSSASKIPSRRLTVLQSAQGLNFLHFAKSTFYTDDIFAAWIAQKLKVHLLVESWQRKNHELPSNCSLPYHVYNIKAIRGPLQS--DFPSHHDHSKWCVST---------KDSQARWTCIGDLNRSPHQALRSGGFICSKNRYIYQSFDRLVSHYASCN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY48-1", "uniprot_id": "DNS2B_MOUSE", "id": "Q9QY48-1", "name": "Deoxyribonuclease-2-beta", "aln": "----MTAKPLRTVLSLLFFALSGVLGTPEISCRNEYGEAVDWFIFYKLPK---RTSKASEEAGLQYLYLDST-RQTWNKSLYLINSTRSALGRTLQHLYDTHNST-NDTAYLIYNDGVPGS--VNYSRQYGHAKGLLVWNRTQGFWLIHSVPKFP-PVH--GYEYPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYS--CFIPSTFHWKLIYMPRMCANSSSLKIPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQKKKQELPSNCSLPYHVYNIKSIGVTSKS--YFSSRQDHSKWCVSI---------KGSANRWTCIGDLNRSLHQALRGGGFICTKNHYIYQAFHKLYLRYGFCK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WZ79-1", "uniprot_id": "DNS2B_HUMAN", "id": "Q8WZ79-1", "name": "Deoxyribonuclease-2-beta", "aln": "MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPK---RQNKESGETGLEYLYLDST-TRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKP--VNYSRKYGHTKGLLLWNRVQGFWLIHSIPQFP-PIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYS--CSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHS--YFSSYQDHAKWCISQ---------KGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZK8-1", "uniprot_id": "DNS2A_RAT", "id": "Q9QZK8-1", "name": "Deoxyribonuclease-2-alpha", "aln": "---------MAAPSSLLLAALLWVP-AEALSCYGDSGRPVDWFVVYKLPAN--SGSGDKPWKGLMYKYMDQN-SEGWQDGVGHIDSKDGAVGLTLQPLYQKNSSQ---LAFLLYNDQPPKSSSAQDSSSRGHTKGVLLLDQEGGFWLVHSVPRFPSPASSGAYSWPPNARTYGQTLLCVSLPFSQFPGIGKQLTYTYPLVYD--HKLEGIFAQKLPDLEEVTKGHHVLREPWNSSVILTSRAGTTFQSFAKFGKFGDDLYSGWLAAALGTNLQVQFWPNSPGILPSNCSGTHKILDVTETGFPGPSGPTFNATEDHSKWCVAP---------EGP---WVCVGDMNRNKRETHRGGGTLCTQVPALWKAFRSLVKACKPC-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56542-1", "uniprot_id": "DNS2A_MOUSE", "id": "P56542-1", "name": "Deoxyribonuclease-2-alpha", "aln": "---------MATLRSLLLAALLWVP-AEALSCYGDSGQPVDWFVVYKLPAH--SGSRDTP-KGLTYKYMDQN-SDGWQDGVGYINSSEGAVGRSLQPLYRKNSSQ---LAFLLYNDQPPKSSSARDSTGHGHTKGVLLLDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYTYPLVYD--HKLEGFFAQKLPDLETVIKNQHVLHEPWNSSVILTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPGILPSNCSGAYQVLDVTQTGFPGPSRLTFSATEDHSKWCVAP---------QGP---WACVGDMNRNKAETHRGGGTVCTQLPSFWKAFQSLVKDWKPCIEGS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00115-1", "uniprot_id": "DNS2A_HUMAN", "id": "O00115-1", "name": "Deoxyribonuclease-2-alpha", "aln": "------------MIPLLLAALLCVP-AGALTCYGDSGQPVDWFVVYKLPAL--RGSGEAAQRGLQYKYLDES-SGGWRDGRALINSPEGAVGRSLQPLYRSNTSQ---LAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPWVYN--YQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSP---------KGP---WTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VED8-1", "uniprot_id": "Q9VED8_DROME", "id": "Q9VED8-1", "name": "", "aln": "-------MRSLCFVLLFVWFFYQNEAKSKVSCKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQNYDTWQMSGKFISDPLSLPAQTLNPLNDDPSHT----LLAAYNDQQPNG---TVFSSGGHAKGVVASDGETAIWIVHSVPKFP---TIPDYSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAGNLPNSCDKSDKVLNVESISNPELS-VDFKTTQDHSKWAVSRPTGILIYHWRVGGGDWICVGDINRQEGQLHRGGGTVCHKSARVSNLYRQLVTNYDKCAQQE---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. : ::* .: *. ***: .**** . ** * *: . * . :.. . . :*: * *** * **:**:: : .:*::**:*.** * :* .. .*: :*::: : :. * * .* : : : . * . : * * * *.* :::: :* * . * .: * **..*. :: :: . : * : .**:**.:: . * *:**:**. : *.** :* : . : : * * ", "identical_positions": 68, "similar_positions": 85, "identity": "17.3%" }, { "cls_id": "homologset.agr.FB:FBgn0000479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UEI1-1", "uniprot_id": "PDE4C_MOUSE", "id": "Q3UEI1-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAES-----------AAHVVFTIG--TQGTQRN----------------------------------------------------------LGSAQSSFDLENG--LPGGKGLLDAQSGPSLGRALQPPVH-HVQRRESFLYRSDSDHEPSPKAVSRTSS-AASD-------------LHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGS----ATRQVLLGTPPHSSQQAAPT----------------------------EDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSR--SGNQVSEYISQTFLDQQAEVELPQP-PTED------------------------DPWPMAQITELRRSSHTS--LPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHP-DAQELLDTLEDNREWYQSRIPCSP------------PHTMG------SDRFKFELTLEEAEEE----------------------------------------------------------------------------------------------------------------------------EEEEDEGQCTALNRESSE-------------------------LPST--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14644-1", "uniprot_id": "PDE4C_RAT", "id": "P14644-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSSRTSS-AASD-------------LHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGS----ATRQALLGTPPQSSQQAAPA----------------------------EESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSR--SGNQVSEYISQTFLDQQAEVELPAP-PTED------------------------HPWPMAQITGLRKSCHTS--LPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHP-DAQELLDTLEDNREWYQSRVPCSP------------PHAIG------PDRFKFELTLEETEEE----------------------------------------------------------------------------------------------------------------------------EEEDERH------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08493-1", "uniprot_id": "PDE4C_HUMAN", "id": "Q08493-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRR-PIRIQQRFYSDPDKSAGCRER-----------DLSPRPELR--KSRLSWP----------------------------------------------------------VSSCRR-FDLENG--LSCGRRALDPQSSPGLGRIMQAPVP-HSQRRESFLYRSDSDYELSPKAMSRNSS-VASD-------------LHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLG---AAKQGPVGNPS-SSNQLPPA----------------------------EDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSR--SGNQVSEYISRTFLDQQTEVELPKV-TAEE------------------------APQPMSRISGLHGLCHSA-SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHP-DAQDLLDTLEDNREWYQSKIPRSPSDL-------TNPERDG------PDRFQFELTLEEAEEED---------------------------------------------------------------------------------------------------------------------------EEEEEEGEETALAKEALE-------------------------LPDTELLSPEAGPDPGDLPLDNQRT-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O89084-1", "uniprot_id": "PDE4A_MOUSE", "id": "O89084-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERSPHRPIERADAVDTGDRPGLR--TTRMSWPSSFHGTGTG--------------------------------------------------GGSSRRLEAENGPTPSPGRSPLDSQASPGL--MLHAGAA-TSQRRESFLYRSDSDYDMSPKTMSRNSS-VASE-------------AHGEDLIVTPFAQVLASLRNVRSNFSLLTNVPIP----SNKRSPLGGPP-SVCKATLS----------------------------EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQHEVEIPSP-TPRQRPFQ------------QPPPAAVQQAQPMSQITGLKKLVHTG-SLN-INVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNRDWYHSAIRQSPSPT-------LEEEPGVLSDPALPDKFQFELTLEEEDEE------------DSLEVPGLPCTEETL---LAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAP---------EESAEAVGHS----FSLETSILPDLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSA-------------------------CSGTSGDNSAVISAPGRWGSGGDPA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54748-1", "uniprot_id": "PDE4A_RAT", "id": "P54748-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYPDSAERSETERSPHRPIERADAVDTGDRPGLR--TTRMSWPSSFHGTGTG--------------------------------------------------GGSSRRLEAENGPTPSPGRSPLDSQASPGL--VLHAGAT-TSQRRESFLYRSDSDYDMSPKAVSRSSS-VASE-------------AHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPIP----SNKRSPLGGPP-SVCKATLS----------------------------EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQNEVEIPSP-TPRQRAFQ------------QPPPSVLRQSQPMSQITGLKKLVHTG-SLN-TNVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMMYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNRDWYHSAIRQSPSPP-------LEEEPGGLGHPSLPDKFQFELTLEEEEEE------------DSLEVPGLPTTEETF---LAAEDARAQAVDWSKVKGPSTTVVEVAERLKQETASAYGAP---------QESMEAVGCS----FSPGTPILPDVRTLSSSEEAPGLLGLPSTAAEVEAPRDHLAATRACSA-------------------------CSGTSGDNSAIISAPGRWGSGGDPA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27815-1", "uniprot_id": "PDE4A_HUMAN", "id": "P27815-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQPHRPIERADAMDTSDRPGLR--TTRMSWPSSFHGTGTGSGG---------------------------------------------AGGGSSRRFEAENGPTPSPGRSPLDSQASPGL--VLHAGAA-TSQRRESFLYRSDSDYDMSPKTMSRNSS-VTSE-------------AHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVP----SNKRSPLGGPT-PVCKATLS----------------------------EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSR--SGNQVSEYISTTFLDKQNEVEIPSP-TMKEREKQQA----PRPRPSQPPPPPVPHLQPMSQITGLKKLMHSN-SLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHP-DAQEILDTLEDNRDWYYSAIRQSPSPP-------PEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSA-------------------------CAGTFGEDTSALPAPGGGGSGGDPT-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08499-1", "uniprot_id": "PDE4D_HUMAN", "id": "Q08499-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP--LPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNG--TSAGRSPLDPMTSPGSGLILQANFV-HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD-------------IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ-DR---APSKRSPMCNQPSINKATIT----------------------------EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEFISNTFLDKQHEVEIPSP-TQKEK---------------------EKKKRPMSQISGVKKLMHSS-SLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNREWYQSTIPQSPSPAPDDP----EEGRQGQ-----TEKFQFELTLEEDGESDTEKD----------------------------------------------------------------------------------------------------------SGS--------QVEEDTSCSDSKTLCTQDSE-----------STEIPLDEQV-----EEEAVGEEEESQPEACVIDDRSPDT----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14270-5", "uniprot_id": "PDE4D_RAT", "id": "P14270-5", "name": "3',5'-cyclic-AMP phosphodiesterase 4D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEGSSVPARAGSHEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQ----LQPPPPPP--LPPPPPPPGATRGRYASSGAS-RVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNG--TSAGRSPLDPMTSPGSGLILQANFV-HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD-------------IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ-DR---APSKRSPMCNQPSINKATIT----------------------------EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQHEVEIPSP-TQKEK---------------------EKKKRPMSQISGVKKLMHSS-SLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNREWYQSTIPQSPSPAPDDQ----EDGRQGQ-----TEKFQFELTLEEDGESDTEKD----------------------------------------------------------------------------------------------------------SGS--------QVEEDTSCSDSKTLCTQDSE-----------STEIPLDEQV-----EEEAVAEEE-SQPQTGVADDCCPDT----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01063-1", "uniprot_id": "PDE4D_MOUSE", "id": "Q01063-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERDTCDVLSRSKS--ASEETLHSCNEEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQADLRSESE-----NIPRPTS--LPLKILPLIAVTSADSS------------------------------------------------------GFDVDNG--TSAGRSPLDPMTSPGSGLILQANFV-HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD-------------IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ-DR---APSKRSPMCNQPSINKATIT----------------------------EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQHEVEIPSP-TQKEK---------------------EKKKRPMSQISGVKKLMHSS-SLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNREWYQSTIPQSPSPAPDDQ----EEGRQGQ-----TEKFQFELTLEEDCESDTEKD----------------------------------------------------------------------------------------------------------SGS--------QVEEDTSCSDSKTLCTQDSE-----------STEIPLDEQV-----EEEAVAEEE-SQPETCVPDDCCPDT----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TUN7-1", "uniprot_id": "A0AB32TUN7_DANRE", "id": "A0AB32TUN7-1", "name": "Phosphodiesterase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAG-NEVTTLVSPGNVTDG------NAPKHLWRQQNPVSLQIQN---SLGSRKNYRVRQRGFSDTEK------YLNPRT--MDRTYAVDTGTR-----------------------------------------PGLKKSRMSWPSSFQGLKRFDVDNG--TSSGRSPLDPMASPGSGLILQANFV-HSQRRESFLYRSDSDYDLSPKSMSRNSS-IASD-------------IHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQER---SNNKRSPMCNPPPITKTSYTVLEVQTLKSKSTDAQLHKTQTKQANGDSEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEYISSTFLDKQNEVEMPSPQSQKDK---------------------EKKKRPMSQISGVKKLTHSS-SLTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNREWYQSTIPQSPSPALDTS----SEGRRAAG----QEKFQFELTLEEDGESDTEKD----------------------------------------------------------------------------------------------------------SGSPPEEDEEEEEEEENSCSDSKTLCTQDSE-----------CTEIPLDEQVGDVPHEDEYEHEENREISEPCVLEEEEEEEEEEEEDTANT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U285-1", "uniprot_id": "A0AB32U285_DANRE", "id": "A0AB32U285-1", "name": "Phosphodiesterase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENMRQRDSL-ISSPLELQSKTSSAIRRRFSGPLLLPPLARRHSALDGKKLKDL-----EALYKSA--LAR---ADTQKET----------------------------------------------------------DFDVENG--LSMGRSSLD--PSPSSGLVLQAN----SQRRESFLYRSDSDFDLSPKTMSRNSS-TASE-------------LHGEDMIVTPFAQVLASLRTVRGNVAALTHMQ-DR---S-NKRPSGTNPQSACKTNLS----------------------------DEAYQKLTVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSR--SGNQVSEFIASTILQKQYDVELLSA-ACKE----------------------EKKRRPMSQISGVRKLSPSP-SLPPTCIPRFGVNTQHESLLAKELEDLDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHP-DAQDILDTLEDNREWYQSMIPRSPSPTPEEHDSRP-TGVTG----SAGEKFQFELTLEEE---DGELE----------------------------------------------------------------------------------------------------------TEEEHT-----DIERSRTMTDPEHPQTSP------------------LGITT---ILDSSERELDQELTSVSALQLETSSSSTHD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HJ32-1", "uniprot_id": "A0AC58HJ32_DANRE", "id": "A0AC58HJ32-1", "name": "Phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWMLWAWLDLQYFQVTLLTDMREWETVHLHATKPLQSHR--AVKRTFSGILQLPRLPRRLSAYGEYSSTTG-----KATFCIG--LPNGLESDTPHGS----------------------------------------------------------SFDVENG--LSVGRSPLDSQASPGSGLVLQANFP-HSQRRESFLYRSDSDFDLSPKAMSRNSS-TASE-------------LHGEDMIVTPFAQVLASLRTVRSNFAVLTHQQ-DR---VPSKKSTGNNPPSMCKTSLP----------------------------EEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSK--SGNQVSEYISSTFLEKQHDMDIMST-PSKEK---------------------EKKKRPMSQISGVKKPTHSS-NIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHP-DAQEILDTLEDNREWYQSMIPHSPTSTPEDKSAVMGMGAMGGGIASAGDKFQFELTLEEEGESDVESP----------------------------------------------------------------------------------------------------------VDEDLT-----SSTRDSSRTDPQGKQTSPAARLLSARSPGCRTMSFKMGEPP---DSEDEDKELDQEGKSVSCLRLGT--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B1AWC9-1", "uniprot_id": "B1AWC9_MOUSE", "id": "B1AWC9-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDG------ISRPTT--LPLTTLPSIAITT------------------------------------------------------VSQECFDVENG--PSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSS-LPSE-------------QHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGA-----PNKRSPAASQAPVSRVSLQ----------------------------EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQNDVEIPSP-TQKDREKK------------------KKQQ-LMTQISGVKKLMHSS-SLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQP-DAQDILDTLEDNRNWYQSMIPQSPSPP------LDERSRD---CQGLMEKFQFELTLEEEDSEG---------------------------------------------------------------------------------------------------------------------------PEKEGEGHSYFSSTKTLC-------------------------VIDPENRDSLEETDIDIATEDKSPIDT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14646-3", "uniprot_id": "PDE4B_RAT", "id": "P14646-3", "name": "3',5'-cyclic-AMP phosphodiesterase 4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDG------ISRPTT--LPLTTLPSIAITT------------------------------------------------------VSQECFDVENG--PSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSS-LPSE-------------QHGDDLIVTPFAQVLASLRIVRNNFTLLTNLHGA-----PNKRSPAASQAPVTRVSLQ----------------------------EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQNDVEIPSP-TQKDREKK------------------KKQQ-LMTQISGVKKLMHSS-SLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQP-DAQDILDTLEDNRNWYQSMIPQSPSPP------LDERSRD---CQGLMEKFQFELTLEEEDSEG---------------------------------------------------------------------------------------------------------------------------PEKEGEGPNYFSSTKTLC-------------------------VIDPENRDSLEETDIDIATEDKSLIDT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07343-1", "uniprot_id": "PDE4B_HUMAN", "id": "Q07343-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDG------ISRPTT--LPLTTLPSIAITT------------------------------------------------------VSQECFDVENG--PSPGRSPLDPQASSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSS-LPSE-------------QHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGT-----SNKRSPAASQPPVSRVNPQ----------------------------EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSR--SGNQVSEYISNTFLDKQNDVEIPSP-TQKDREKK------------------KKQQ-LMTQISGVKKLMHSS-SLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQP-DAQDILDTLEDNRNWYQSMIPQSPSPP------LDEQNRD---CQGLMEKFQFELTLDEEDSEG---------------------------------------------------------------------------------------------------------------------------PEKEGEGHSYFSSTKTLC-------------------------VIDPENRDSLGETDIDIATEDKSPVDT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JV44-1", "uniprot_id": "A0AC58JV44_DANRE", "id": "A0AC58JV44-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSRIQKHTHRCVNYKLIFPSNSFCPSVPDLSRRIVKGSPSKLYPEASLSRASKECQRSRPVQDRERKTSQKMRKSRSVLTVSPNEDSKEPPDSRLSESFTSSGCTLGVDLRRRRRRFSGNLQLPPLSWRQMERSRSPDDEF------MARPTT--LPFITPPRIDITP------------------------------------------------------VDTECFDVENG--PSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSDSDYDLSPKSMSRNSS-VASE-------------LHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQCT-----SNKRSPVSNQPSITRVCLP----------------------------DESYQKLAVETMEELDWCLDQLETIQTYRSVSDMASNKFKRMLNRELTHLSEMSR--SGNQVSEFISNTFLDKQNDVEIPSP-TPKAREKK------------------KKQQ-LMTQISGVKKVSHG--PSLNCGIARFGVKTDKEDLLSKELEDLNRWGLNIFTVSEYSNNRPLTCIMYAIFQERDLLKTFKIPTDTFVTYMMTLEDHYHQDVAYHNSLHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLTKKQRTSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEDNRNWYQSMIPQSPSPP------FYQPDKEGNGGSSGPDKFQFELTLEEEDSEG---------------------------------------------------------------------------------------------------------------------------TEKDEQSQ----GDEEEE-------------------------AEEDRGEEMESTTHIQIVTEDASPVDT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3APY5-1", "uniprot_id": "A0A8M3APY5_DANRE", "id": "A0A8M3APY5-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKSQSVLAVTPVDDSKD-----LSG-CTSSGATLGVDLWRCPRRHSGTLVLPPLSWRQAERARSPQEDN------VSRPTS--LGFITPPRIDITP------------------------------------------------------VPPDSLEVENG--PSIGCSPLDLQVSPASGLILHPSMASHSQRRESFLYRSDSDYDLSPKSTSRNSSLVGEQ-------------LHGEDLIVTPFAQVLASLRTVRNNFSILTNVSCP-----SSKRSPISSHGPVTKANLS----------------------------DESYQKLALETMEELDWCLDQLETIQTYRSVSDMASNKFKRMLNRELTHLSEMSR--SGNQVSEFISNTFLDKQNELEIPLS-TPKSRERK------------------KRQQQLMTQISGVRKVTHGSGPSSSCSTTRFGVKTDSEDMLSKDLEDINKWGLNIFKVAEHSHHRPLACIMYAIFQERDLMKTFKIPVDTFVTYMMTLEDHYHADVAYHNSLHAADVAQSTHILLSTPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQGENCDLFQNLSKKERQTLRKMVIHMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKPLDLYKQWTDRIMQEFFHQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEENRNWYYSMIPQSPSPP------FFEA------GSPSGDKFQFELEVEEGAKQD---------------------------------------------------------------------------------------------------------------------------TKN------------------------------------------------LSKTDCVEIVTHSTLFSET---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4T4-1", "uniprot_id": "PDE4A_DROME", "id": "Q9W4T4-1", "name": "3',5'-cyclic-AMP phosphodiesterase, isoform I", "aln": "MMRLARFTQGFSFNKNVAKHRGSGSSNGTGNGSGTGNGQGLGGSCSANGLAATGGVGGGGGSGSGGGGCGSGSGSGSGKRKSKARTKCFGGTVFRCCLPCRGGGSAAPATSPPQTPAQTPDELKVIPEDCNLEKSAEQKRDLLERNNKEDDLLNRTVSGSELDLYGGAGGGTKKHSLADTIDTSVTTPISLKTLINDVDEELDQQLSAADIAAASLASGLVARRAEPETLSDASVSPTAVVQQQQQQQQQLQQPLLQSQPHFVPSSGNILSQVTLYSGSNPSTNPCQSAVQNQGQNSNPNPNQNPNTNPNQNQQRCSCQPQTSPLPHIKEEEESDQANFKHQTSLKEHQPLPPPITIATGYCGSCESVHHSSATSSSAGTVPPGGQQTQEYIAGTSSTPSPRIKLKFRKPHKSCWSRIVLAPIGSAGGSSSATTVIGSNSNETLASSSTTGGTATTTQNSSSVSVAAHHRLTSSSASALATSHPSNSQLLPTSKMQAEQGSIGDLQKYHSRYLKNRRHTLANVRFDVENG---QGARSPLEG-GSPSAGLVLQNLP----QRRESFLYRSDSDFEMSPKSMSRNSS-IASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLS--------------------------QGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSR--SGNQISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHP-DAQDILDTLEENRDYYQSMIPPSPPPS------GVDENPQ-------EDRIRFQVTLEESDQENLAELE------------------------------------------------------------------------------------------------------------------EGDESGGESTTTGTTGTTAASALSG----------------------AGGGGGGGGGMAPRTGGCQNQPQHGGM---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLD----------------------SLMVALYKDRVSPFPNVHNFETGVSIVLYDP----SKFQLSVRQLDVLFKRFFP------------------------------SFNISAIDHTRE-----ENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLND-------------------------------SKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAIG---HDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHREL-FQQLLSEHWPQLLSISKKK----FDFISEAILATDMALHS---------------QYEDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFN---DCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNA-------LSQKFSGLKFLSDNVKINKEYWMKHKKPQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .::*: : : ::.: *:. :: . . : * ::*: :: . ..:. ::.*: : .: . . *. . :. : : :: : : :.. : . :. . . : * . ::. . .. *. ..: : ** * :** ** ** *:: * : . * : * :. ***.*** .**:* * .**:* ::: *:***.* : *: * : : .: :: : . :*:***: * . *: :* .:* :: :::.**:** ::.* : :*. : ** * :. : ::. . .:*. . ..: : .::..* * . : :.: :: . . ::. : :.. ", "identical_positions": 61, "similar_positions": 156, "identity": "4.34%" }, { "cls_id": "homologset.agr.FB:FBgn0000482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFJ4-1", "uniprot_id": "B5DFJ4_RAT", "id": "B5DFJ4-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDEYEDSLSRSAVLQTGCPSVGIPHSGYVNAHLEKEVPIFTKQRIDFTPSE----RITSLVVSCSQLCMSLG---KDTLLRIDLGKASEPNRVELGRKDDA---KVHKMFLDHTGSHLLVALS--------STEVLYMNRNGQ------KARPLARWKGQLVESVGWNKALGSESSTGPILVGTAQG-QIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRGFVIATTRQRLFQFIGRAVEDAEAQGFSGLFAAYTD--HPPPFREFPGNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGSLDCGR---------PDSLLSEEKV---WEYPAGIGPG---ANPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEK-FGPLRH--------MVKDSSTGHLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQHRYLESARCYALTQS---YFEEIALKFLEARQEEALAEFLQRKLAGLKPT----------ERTQATLLTTWLTELYLSRLGALQGDPDALNLYRDTRECFRTFLSSPRHKEWLFA----------SRASIHELLASHGDTEHMVYFAVIMQDYERVVTYHCQHEAYEEALAVLARHRDPQLFYKFSPVLIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGDAQQV----------SQAIRYMEFCVNVLGETEQAIHN--YLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ---VDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCP----LLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCSTCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPTYKQARLEELQRKLGTAPPPTKGSVKAKEAEAGAAAVGP-SREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQHYEEEHLSWL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R307-1", "uniprot_id": "VPS18_MOUSE", "id": "Q8R307-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDEYEDSLSRSAVLQTGCPSVGIPHSGYVSAHLEKEVPIFTKQRVDFTPSE----RITSLVVSCNQLCMSLG---KDTLLRIDLGKASEPNRVELGRKDDA---KVHKMFLDHTGSHLLVALS--------STEVLYMNRNGQ------KARPLARWKGQLVESVGWNKAMGNESSTGPILVGTAQG-QIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRGFVIATTRQRLFQFIGRAVEDTEAQGFAGLFAAYTD--HPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGSLDCGR---------PDSLLSEERV---WEYPAGVGPG---ANPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEK-FGPLRH--------MVKDSSTGHLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQHRYLESARCYALTQS---YFEEIALKFLEARQEEALAEFLQRKLAGLKPT----------ERTQATLLTTWLTELYLSRLGALQGDPDALTLYRDTRECFRTFLSSPRHKEWLFA----------SRASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEAQQV----------SQAIRYMEFCVNVLGETEQAIHN--YLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ---VDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCP----LLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCSTCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPTKGSVKAKEAEAGAAAVGP-SREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQRYEEEHLSWL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P253-1", "uniprot_id": "VPS18_HUMAN", "id": "Q9P253-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDEYENSLSRSAVLQPGCPSVGIPHSGYVNAQLEKEVPIFTKQRIDFTPSE----RITSLVVSSNQLCMSLG---KDTLLRIDLGKANEPNHVELGRKDDA---KVHKMFLDHTGSHLLIALS--------STEVLYVNRNGQ------KVRPLARWKGQLVESVGWNKALGTESSTGPILVGTAQG-HIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRSFVIATTRQRLFQFIGRAAEGAEAQGFSGLFAAYTD--HPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGALDCGR---------PDSLLSEERV---WEYPEGVGPG---ASPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEK-FGPLKH--------MVKDSSTGQLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQRRYLESARCYALTQS---YFEEIALKFLEARQEEALAEFLQRKLASLKPA----------ERTQATLLTTWLTELYLSRLGALQGDPEALTLYRETKECFRTFLSSPRHKEWLFA----------SRASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEVQQV----------SQAIRYMEFCVNVLGETEQAIHN--YLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ---VDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCP----LLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPAKGSARAKEAEGGAATAGP-SREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQRYEEEQLSWL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59015-1", "uniprot_id": "VPS18_DANRE", "id": "P59015-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDQYEDSQNIRQHSRMSTANIGITHSGFVNVRLEEEKPIFTKQRIDFSPPE----KINQFSVCNNQLCMSLG---KDTLLRIDLGKPDQPNQIELGRKDDS---KVHRLFLDPTGSHLVICLT--------TNECVYLNRNTQ------KVRGLSRWRGHLIESIGWNKLIGSETNTGPILVGTSQG-IIFEAEISASEGSLFNTNPDQYFRQVHYLEEDGKPAPVCCLEVERGLETKYFIIATTRKRLFQFVGKLAEGSEQQGFSSIFAQNQD--LLPSFQEFPVNMGYSEITFYTSKLRSRPKTFAWMMGNGVLYGQLDYVR---------PDSLLSDVQV---WEYTQDIDLN---FVKPISIVLTQFHFLLLLPDRVRGICTLNGQVVHEDVFPEK-FGTLQK--------MIKDPITGLVWIYTEKAVFRYHIQKEARDVWQMYMNMNKFDLAKEYCKDRPECLDMVLAKEAEHCFQNKRYLESAKCYALTQN---YFEEIALKFIEAKQEEALKEFLIKKLVNLKPS----------EKTQITLLVTWLTELYLNRLGQLEADEGKQHLFLETREEFRTFLKSPKHKDCFYN----------NRSTIYDLLASHGDVDNMVYFSVIMQDYERVISHYCQHDDYSAALDVLSKHCDDKLFYKFSPVLMQHIPKKVVDAWIQMGNRLDPKNLIPALVNYSQMGSMQQI----------NETIRYMEFCVYELDVKEEAIHN--YLLSLYAKHKPDALLWYLEQAGTHVSDIHYDLKYALRLCSEHGYLQACVLVYKIMELYEEAVDLALK---VDVDLAKSCADLPEDDEELRKKLWLKIARHVVQEEKDVKKAMNCLSSCN----LLKIEDILPFFPDFVTIDHFKEAICSSLEEYNKHIEELKQEMEEATESAKRIREDIQEMRNKYGVVESQEKCATCDFPLLNRPFYLFLCGHMFHYDCLLQEVIPHLSVYKQNKLDELQKKLAATTQTTKARHKPREEDTVSLGKGQGSREQIKSDIDDIIACECVYCGELMIKSIDKPFIDPQKFDQEMSSWL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24314-1", "uniprot_id": "VPS18_DROME", "id": "Q24314-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "MDTSMPNQPKFLPRIEHNSSGATANSYVATASGNPFETDEEDEIFSRHKMVLRVPSNCTGDLMHLAVSRNWLVCLLGTPERTTLLRFFLPRAIPPGEAVLEKYLSGSGYKITRMFLDPTGHHIIIALVPKSATAGVSPDFLYIHCLESPQAQQLKVRRIEKFKDHEITAVAFNPYHGNESSTGPILLGTSRG-LIFETELNPAADGHVQR------KQLYDLGLGRPKYPITGLKLLRVPNSSRYIIVVTSPECIYTFQETLKAEE-RSLQAIFAGYVSGVQEPHCEERKTDLTFSQLRFFAPPNSKYPKQWAWLCGEGIRVGELSIEAN-------SAATLIGNTLINLDFEKTMHLSYGERRLNTPKAFVLTEYHAVLLYADHVRAICLLNQEQVYQEAFDEARVGKPLS--------IERDELTGSIYVYTVKTVFNLRVTREERNVWRIYLDKGQYELATAHAAEDPEHLQLVLCQRADAAFADGSYQVAADYYAETDK---SFEEVCLKFMVLPDKRPIINYVKKRLSRVTTKPMETDELDEDKMNIIKALVIWLIDLYLIQINMPDKDEE---WRSSWQTEYDEFMMEAHVLSCTRQ----------NRETVRQLIAEHADPRNMAQFAIAIGDYDEVVAQQLKAECYAEALQTLINQRNPELFYKYAPELITRLPKPTVDALMAQGSRLEVEKLVPTLIIME---NREQR----------EQTQRYLEFAIYKLNTTNDAIHN--FLLHLYAEHEPKLLMKYLEIQGRDESLVHYDIYYAHKVCTDLDVKEARVFLECMLRKWISAVDLALT---FDMKLAKETASRP-SDSKIRRKLWLRIAYHDIKGTNDVKKALNLLKECD----LLRIEDLLPFFADFEKIDNFKEAICDALRDYNQRIQELQREMAETTEQTDRVTAELQQLRQHSLTVESQDTCEICEMMLLVKPFFIFICGHKFHSDCLEKHVVPLLTKEQCRRLGTLKQQLEAEVQTQAQPQSGALSKQQAMELQR-KRAALKTEIEDILAADCLFCG-LLISTIDQPFVD--DWEQVNVEWE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27801-1", "uniprot_id": "PEP3_YEAST", "id": "P27801-1", "name": "Vacuolar membrane protein PEP3", "aln": "--------------------------------MIKTRIEEVQLQFLTGNT----------ELTHLKVSNDQLIVTTQR----TIYRINLQDPAIVNHFDCPLSKEL--ETIMNVHVSPMGSVILIRTN----------FGRYMLLKDG------EFTQLNKIKNLDLSSLHW-------INETTFLMGIKKTPKLYRVELTG-----------------------KDITTKLWYENKKLSGGIDGIAYWEGSLLLTIKDNILYWRDVTNMKFPLVLPDE-------SEQFERLKHHAIKKFDS----YNGLFAWVTSNGIVFGDLKEKQMEKDPASNNFGKFLSSSKVLLNFELPDYQNDK---DHLIKDIVLTAFHILLLRKNTVTMVSQLNNDVVFHETIPRHQLTGSNTDSNEKFLGLVRDSVKETFWCFSNINVFEIIIENEPNSVWNLLVRDNKFDKALSLKGLTVREIESVKLSKAMYLFHTAKDFHSAAQTLGSMKDLSHFGEIALNFLQIKDYNDLNVILIKQLDNVPWK------------STQVVLSSWIIWNFMKQLNDIELKINTTKPASTDEDNLLNWNLNLKEKSNELTKFLESHLEKLDNETVYQIMSKQNRQNELLIFASLINDMKFLLSFWIDQGNWYESLKILLTINNHDLVYKYSLILLLNSPEATVSTWMKIKD-LDPNKLIPTILKFFTNWQNNSKLITNISEYPENYSLTYLKWCVREVPKMCNPIVYNSILYMMITDPRNDMILENDIIKFMKSNENKYDLNFQLRLSLKFKKTKTSIFLLTRLNLFEDAIDLALKNNLIDDCKVIVNDEILIEDYKLRKRLWLKIAKHLLLSMKDIDIKQLIRTILNDSNEILTIKDLLPFFNEYTTIANLKEELIKFLENHNMKMNEISEDIINSKNLKVEINTEISKFNEIYRILEPGKSCDECGKFLQIKKFIVFPCGHCFHWNCIIRVILNSNDYNLRQKTENFLKAKSKHN---------------------------LNDLENIIVEKCGLCSDININKIDQPISID---ETELAKWNE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * . : : *. . * *: *: * . .. . .: .:.:. * ::: *: : : : :. : :: : . .:*:* : ::..*:. . : : : : . : .: :. . * : . : : . :**: .:*: * *. .::.. : :* . . :*** :* :** : * :. *. : * .: : . . : :* . .: :: **. : .* ..**. : .::: * :: * .* * :* : . * *:.*:*: : . : : ::* : . * *: :: ::. : . . : . : . .. :: ::::.: .: *: : * . ::: . : :* * : .*.**:: *: . *. *.: : . *: .:*:*::: . :. . : *:::.: : :.* * : : . :: :**: : ::. . .: : : :. : .*:**** .* . . .* ::*::***:** * : :*:. :* *:*:**** :: .* ::** : . *. :* :::*:..:: ::. .: ::.::. :*. ..* * * : * :* *** ** :*: : : : : : ::::::. .* *. : * .**:*: : .* ", "identical_positions": 110, "similar_positions": 285, "identity": "10.29%" }, { "cls_id": "homologset.agr.FB:FBgn0000489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05986-1", "uniprot_id": "KAPC_YEAST", "id": "P05986-1", "name": "cAMP-dependent protein kinase type 3", "aln": "---------------------------------------------------------------------------------------------------------------------MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSSNTPVEINGRNSGKLKEEASAGIC---LVKKPMLQYRDTSGKYS------------------------------------------------------------------------LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQ----------------NGSEDVKNHPWFNE------------------------VIWEKLLARYIETPYEPPIQQGQG--------DTSQ---------FDRYPEEEFNYGIQGE---------------DPYMDLMKEF--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06244-1", "uniprot_id": "KAPA_YEAST", "id": "P06244-1", "name": "cAMP-dependent protein kinase type 1", "aln": "---------------------------------------------------------------------------------------------------------------------MSTEEQNGGGQKSLDDRQGEESQKG----ETSERETTATESGNESKSVEKEGGETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYS------------------------------------------------------------------------LQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQ----------------NGTEDVKNHPWFKE------------------------VVWEKLLSRNIETPYEPPIQQGQG--------DTSQ---------FDKYPEEDINYGVQGE---------------DPYADLFRDF--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06245-1", "uniprot_id": "KAPB_YEAST", "id": "P06245-1", "name": "cAMP-dependent protein kinase type 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------MEFVAERAQPVG---QTIQQQNVNTYGQGVLQPHHDLQQRQQQQQQRQHQQLLT-----SQLPQKSLVSKGKYT------------------------------------------------------------------------LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQ----------------SGSRDIKAHPWFSE------------------------VVWERLLAKDIETPYEPPITSGIG--------DTSL---------FDQYPEEQLDYGIQGD---------------DPYAEYFQDF--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0G2K247-1", "uniprot_id": "A0A0G2K247_RAT", "id": "A0A0G2K247-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MEPPACAEAAVKDPAARDHDPVDAKIS--APAAD------PLPRTSS-QKEGHS------------------------------------------------------------------------LQDWDTIATVGTGTFGRVNLVKEKTGRRYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTDHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVAAIFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKCVCFLSRMGQKTSSGTGGSEVWSGSPCHRGNLSHPLCPSYPVMVTSPTLRLIQRVSWTRLLLYLMKIWKHSKISEDENSCLQEVCEDIHTTLMTRTVLLLYPFLAVKLEGLVCVCGCVYASSCNVNTIHHPWDPASFQQLETCPVKISQKLLNCRFSPSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922R0-1", "uniprot_id": "PRKX_MOUSE", "id": "Q922R0-1", "name": "cAMP-dependent protein kinase catalytic subunit PRKX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MEPPAGAAATVKDP---DHDPVKTKVS--APAAD------PKPRTSS-QKAGHS------------------------------------------------------------------------LQDWDTIATVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMK----------------NGAEDIKRHRWFRG------------------------VEWESVPQRKLKPPIVPKLSGDG---------DISN---------FETYPESELDKTPSVS---------------DKDLETFKNF--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51817-1", "uniprot_id": "PRKX_HUMAN", "id": "P51817-1", "name": "cAMP-dependent protein kinase catalytic subunit PRKX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MEAPGLAQAAAAES---DSRKVAEETPDGAPALC------PSPEALSPEPPVYS------------------------------------------------------------------------LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMK----------------NGANDVKHHRWFRS------------------------VDWEAVPQRKLKPPIVPKIAGDG---------DTSN---------FETYPENDWDTAAPVP---------------QKDLEIFKNF--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16912-1", "uniprot_id": "KAPC3_DROME", "id": "P16912-1", "name": "cAMP-dependent protein kinase catalytic subunit 3", "aln": "MDLWHIFLERILVACRVSASVFANFGCGLYSSWKLICGDHDSASGLRAGLATPTQRGKATGDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPA------TNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMK----------------NGADDVKRHRWFKH------------------------LNWNDVYSKKLKPPILPDVHHDG---------DTKN---------FDDYPEKDWKPAKAVD---------------QRDLQYFNDF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * *:: : *:***:**** * :. :: *:* : ::::** :*.::*: :* : ***:* : : :* ::*::::: *****: **: :*.. .. **::*: *:****: :*:********:*::::**:*:******* : *:******:*:***:: :* :.:::***::*:**:*** *:.**:: .: *::** :: : :. **:.:*:. * :.*:**:: .*: . . : * : :: . : . * : : . . :.:: ", "identical_positions": 97, "similar_positions": 114, "identity": "14.22%" }, { "cls_id": "homologset.agr.FB:FBgn0000490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06826-1", "uniprot_id": "BMP4_RAT", "id": "Q06826-1", "name": "Bone morphogenetic protein 4", "aln": "MIPGNRMLMVVLLCQVLLGGAT--------DASLIPETGKKKVAEIQGH---AGGRRSG-------------------------------------------------------------QSHELLR-------------------------------------------------------------------------------------------------DFEATLLQMFGLRRRPQPSKS-AVIPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASRANTVRSFHHEEHLENIPGTSESSAFRFFFNLSSIPENEVISSAELRLFR----EQVDQGPDWEQGFH-RINIYEVMKPPAEMVPGHLITRLLDTRLVRHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHTLTRRR------------AKRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN-SSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21275-1", "uniprot_id": "BMP4_MOUSE", "id": "P21275-1", "name": "Bone morphogenetic protein 4", "aln": "MIPGNRMLMVVLLCQVLLGGAS--------HASLIPETGKKKVAEIQGH---AGGRRSG-------------------------------------------------------------QSHELLR-------------------------------------------------------------------------------------------------DFEATLLQMFGLRRRPQPSKS-AVIPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASRANTVRSFHHEEHLENIPGTSESSAFRFLFNLSSIPENEVISSAELRLFR----EQVDQGPDWEQGFH-RINIYEVMKPPAEMVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGDWAQLRPLLVTFGHDGRGHTLTRRR------------AKRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN-SSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12644-1", "uniprot_id": "BMP4_HUMAN", "id": "P12644-1", "name": "Bone morphogenetic protein 4", "aln": "MIPGNRMLMVVLLCQVLLGGAS--------HASLIPETGKKKVAEIQGH---AGGRRSG-------------------------------------------------------------QSHELLR-------------------------------------------------------------------------------------------------DFEATLLQMFGLRRRPQPSKS-AVIPDYMRDLYRLQSGEEEEE-QIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFR----EQVDQGPDWERGFH-RINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRR-----------AKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN-SSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49001-1", "uniprot_id": "BMP2_RAT", "id": "P49001-1", "name": "Bone morphogenetic protein 2", "aln": "MVAGTRCLLVLLLPQVLLGGA----------AGLIPELGRKKFAGAS-----RPLSRP---------------------------------------------------------------SEDVLS-------------------------------------------------------------------------------------------------EFELRLLSMFGLKQRPTPSKD-VVVPPYMLDLYRRHSGQPGALAPDHR-----LERAASRANTVLSFHHEEAIEELSEMSGKTSRRFFFNLSSVPTDEFLTSAELQIFR----EQMQEALGN-SSFQHRINIYEIIKP-ATASSKFPVTRLLDTRLVTQNTSQWESFDVTPAVMRWTAQGHTNHGFVVEVAHLEEKPGVSKRHVRISRSLHQDEHSWSQVRPLLVTFGHDGKGHPLHKRE-------------KRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN-SKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21274-1", "uniprot_id": "BMP2_MOUSE", "id": "P21274-1", "name": "Bone morphogenetic protein 2", "aln": "MVAGTRCLLVLLLPQVLLGGA----------AGLIPELGRKKFAAASS----RPLSRP---------------------------------------------------------------SEDVLS-------------------------------------------------------------------------------------------------EFELRLLSMFGLKQRPTPSKD-VVVPPYMLDLYRRHSGQPGAPAPDHR-----LERAASRANTVRSFHHEEAVEELPEMSGKTARRFFFNLSSVPSDEFLTSAELQIFR----EQIQEALGN-SSFQHRINIYEIIKP-AAANLKFPVTRLLDTRLVNQNTSQWESFDVTPAVMRWTTQGHTNHGFVVEVAHLEENPGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKRE-------------KRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN-SKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12643-1", "uniprot_id": "BMP2_HUMAN", "id": "P12643-1", "name": "Bone morphogenetic protein 2", "aln": "MVAGTRCLLALLLPQVLLGGA----------AGLVPELGRRKFAAASSG---RPSSQP---------------------------------------------------------------SDEVLS-------------------------------------------------------------------------------------------------EFELRLLSMFGLKQRPTPSRD-AVVPPYMLDLYRRHSGQPGSPAPDHR-----LERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFR----EQMQDALGNNSSFHHRINIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKRE-------------KRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN-SKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07713-1", "uniprot_id": "DECA_DROME", "id": "P07713-1", "name": "Protein decapentaplegic", "aln": "MRAWLLLLAVLATFQTIVRVASTEDISQRFIAAIAPVAAHIPLASASGSGSGRSGSRSVGASTSTALAKAFNPFSEPASFSDSDKSHRSKTNKKPSKSDANRQFNEVHKPRTDQLENSKNKSKQLVNKPNHNKMAVKEQRSHHKKSHHHRSHQPKQASASTESHQSSSIESIFVEEPTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPK-----PGLLTKSANTVRSFTHKDSKIDD-RFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQ-REPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRP-TRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * .: *.:: * *.: * .: .* . :. *.::: ::* **.:*.::: * .:. ::* * .** *. :. **** ** *:: : . *: *::.*:* :* :.:***:: * :*: . . : :: :*:: : . ****: * * : ::** *** ** . : *:*: :** :.. :***: ** : * : :***.*: .**: :. * **..:: * : :. .*:**.**********:****** **.*:****.********:******:******.:* ..:********:*.:::****:: ..*******:*.* *****", "identical_positions": 143, "similar_positions": 117, "identity": "23.99%" }, { "cls_id": "homologset.agr.FB:FBgn0000492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28360-1", "uniprot_id": "MSX1_HUMAN", "id": "P28360-1", "name": "Homeobox protein MSX-1", "aln": "-------------------------------------------------------------------------MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGA---------KESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVG-YSMYHLT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13297-1", "uniprot_id": "MSX1_MOUSE", "id": "P13297-1", "name": "Homeobox protein MSX-1", "aln": "-------------------------------------------------------------------------MAPAAAMTSLPLGVKVEDSAFAKPAGGGVGQAPGAAAATATAMGTDEEGAKPKVPASLLPFSVEALMADHRKPGA---------KESVLVASEGAQAAGGSVQHLGTRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKLDRTPWMQSPRFSPPPARRLSPPA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYSASGPFQRAALPVAPVGLYTAHVG-YSMYHLT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35548-1", "uniprot_id": "MSX2_HUMAN", "id": "P35548-1", "name": "Homeobox protein MSX-2", "aln": "------------------------------------------------------------------------------------MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEE---RRVKVSSLPFSVEALMSDKKPP-----------KEASPLPAE---SASAGATLRPLLLSGHGAREAHSPGPLVKPF---------ETASVKSENSE--DGAAWMQEPGRYSPPPRHMSPTT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSS-FSLPFPIS----SPLQ-AASIYGASYPFHRPVLPIPPVGLYATPVG-YGMYHLS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03358-1", "uniprot_id": "MSX2_MOUSE", "id": "Q03358-1", "name": "Homeobox protein MSX-2", "aln": "------------------------------------------------------------------------------------MASPTKGGDLFSSDEEGPAVLAGPGPGPGGAEGSAEE---RRVKVSSLPFSVEALMSDKKPP-----------KESPAVPPD---CASAGAVLRPLLLPGHGVRDAHSPGPLVKPF---------ETASVKSENSE--DGAPWIQEPGRYSPPPRHMSPTT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSG-FSLPFPIN----SPLQ-AASIYGASYPFHRPVLPIPPVGLYATPVG-YGMYHLS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01704-1", "uniprot_id": "MSXD_DANRE", "id": "Q01704-1", "name": "Homeobox protein MSH-D", "aln": "----------------------------------------------------------------------------------------------------------------------MEQ---RKTQVSSHPFSVESLISSHKTN-----------KDFERRRED---VSSQ--------FAQTEIRDSCGSAGIPKHFML-------QTSPVKSESPEPDDCTSWVMN-SRYS-QTRQESP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------CPLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLTLTETQVKIWFQNRRAKAKRLQEAELEKLKLTAKPALHPN-FSLPLPLG----TQLHSAVSLYGQSYPYQRPLLPVAPVGLYGTPLG-YSMYHLA---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03356-1", "uniprot_id": "MSXB_DANRE", "id": "Q03356-1", "name": "Homeobox protein MSH-B", "aln": "------------------------------------------------------------------------------------------MNSPKGPVETTSQEKSESDSEESQKPRDMTADTGHKAKKTYLPFSVESLMAKSSCQ-----------QVACSP---ALQHQRMGHGQDLVRT--YFVEKAKVSVDTLSSVS--------DSLNDDSEELSDKEQSTWSNSSSFTS-PPRHPSPTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFSTSQLLSLERKFRQKQYLSIAERAEFSNSLNLTETQVKIWFQNRRAKAKRLQEAELEKFKCASKPLL--APFALPFPLGS--------PSSLYGPPASFPRP-VPMP--GLFNGPVS-YGMYYLS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01703-1", "uniprot_id": "MSXC_DANRE", "id": "Q01703-1", "name": "Homeobox protein MSH-C", "aln": "-----------------------------------------------------------------------------------MAPLSSMMNSLQGPLSQEGKLQERKSDKEDAQSNDKAAVKGCKGKALSLPFSVESLISDRTSS-----------RTLYTSSEAGIISPTSGADERLKLSPMALYADRKIPVESVSNLS--------DCKRGDMEELSDKGQSGWFQTTSYTS-PPRHSSPPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKNNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSNSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKLATKPLL--PAFAFPFPLGTH-----VGSPPLYGPSSSFPRPALPVP--GLFGGPVT-YGMYYLS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V8C7-1", "uniprot_id": "G3V8C7_RAT", "id": "G3V8C7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MARATLDMNAAGLEARGGGHIEQGPLPFSVESLLEA----------------------------------------------------ERVRGSE--------SGELGEERPPGASKPGAWPPPVAHSC-PPRAPSPPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKLTAKPLLP-AAFALPFPLGT----------QLHSSAATFGGN--AVP--GILAGPVAAYGMYYLS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70354-1", "uniprot_id": "MSX3_MOUSE", "id": "P70354-1", "name": "Homeobox protein MSX-3", "aln": "----------------------------------------------------------------------------------------------------------MARATFDMNAAGLEARGGGHTEHGPLPFSVESLLEA----------------------------------------------------ERVPGSE--------SGELGVERPLGASKPGAWPPPVAHSC-PPRAPSPPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKLAAKPLLP-AAFALPFPLGT----------QLHSSAATFGGN--AVP--GILAGPVAAYGMYYLS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03357-1", "uniprot_id": "MSXA_DANRE", "id": "Q03357-1", "name": "Homeobox protein MSH-A", "aln": "-------------------------------------------------------------------------------------------MVLTQNVDTFSGMISANHKSKVSSDEDDDDHGSRSVRTQSLPFSVDALMSTKERS--------------------------------ESTSQGSIHMTRIINQDDRSIYS--------DSVDFIKRRESAKEDSAWINKPRLST-SPRSQSPTI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------CPLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELERFKMASKPILHPG-LTLPFPLCT----QPQTAALVCGQSFPFSRHMLPFAPIGIYSTPMG-YSMCHLSKDGYSVEPV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03372-1", "uniprot_id": "HMSH_DROME", "id": "Q03372-1", "name": "Muscle segmentation homeobox", "aln": "MLKLSPASMTVTGLRQTMTSPTVPPSSNTPAGNLIITSSSSNSGSNSGSNMSSGNMTSSNLTNLSPSHPAGLNALASPTSPSALLLAHQQHLLQQHQQHQQQQQQQQQAAALQLAAVHPPAHHLHKTTSRLSNFSVASLLADTRPRTPPNQAADGPQNLTSSAATSPISQASSTPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQADARANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAEIEKIKMAALGRGAPG--------------------AQWAMAGYFHPSLMHLG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :*: . . *. * ***** ********:* ***:**:**::*************.** ************************:*::* :: . . : . ", "identical_positions": 68, "similar_positions": 20, "identity": "12.1%" }, { "cls_id": "homologset.agr.FB:FBgn0000499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVB9-1", "uniprot_id": "DVL1_RAT", "id": "Q9WVB9-1", "name": "Segment polarity protein dishevelled homolog DVL-1", "aln": "----------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPP--------PLERTGGIGDSRPPSFHPNVAS-SRDGMDNETGTESMVSHRRERAR---RRNRDEAARTNGHPRGDRR-RELGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLIRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGA-PQLEEAPLTV-KSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCS----NLASLNLNS--GSSGA-SDQDTLAPLPHPSV-PWPLG--QGYPYQYP-GPPPCFPPAYQDPG-FSYGSGSAGSQQSEGSKSSGSTRSS---HRTPGRE-ERRATG--------AGG-----SGSESDHTVP----SGSGSTGWWERPVSQLSRGS------------------SPRSQASAVAP-GLPPLHPLTKAY---------AVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFF--VDIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51141-1", "uniprot_id": "DVL1_MOUSE", "id": "P51141-1", "name": "Segment polarity protein dishevelled homolog DVL-1", "aln": "----------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPP--------PLERTGGIGDSRPPSFHPNVAS-SRDGMDNETGTESMVSHRRERAR---RRNRDEAARTNGHPRGDRR-RDLGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLVRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGA-PQLEEAPLTV-KSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCS----NLASLNLNS--GSSGA-SDQDTLAPLPHPSV-PWPLG--QGYPYQYP-GPPPCFPPAYQDPG-FSCGSGSAGSQQSEGSKSSGSTRSS---HRTPGRE-ERRATG--------AGG-----SGSESDHTVP----SGSGSTGWWERPVSQLSRGS------------------SPRSQASAVAP-GLPPLHPLTKAY---------AVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFF--VDIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14640-1", "uniprot_id": "DVL1_HUMAN", "id": "O14640-1", "name": "Segment polarity protein dishevelled homolog DVL-1", "aln": "----------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPP--------PLERTGGIGDSRPPSFHPNVAS-SRDGMDNETGTESMVSHRRERAR---RRNREEAARTNGHPRGDRR-RDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGA-PQLEEAPLTV-KSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCS----NLATLNLNS--GSSGT-SDQDTLAPLPHPAA-PWPLG--QGYPYQYP-GPPPCFPPAYQDPG-FSYGSGSTGSQQSEGSKSSGSTRSS---RRAPGREKERRAAG--------AGG-----SGSESDHTAP----SGVGSS-WRERPAGQLSRGS------------------SPRSQASATAP-GLPPPHPTTKAY---------TVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFF--VDIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54792-1", "uniprot_id": "DVLP1_HUMAN", "id": "P54792-1", "name": "Putative segment polarity protein dishevelled homolog DVL1P1", "aln": "----------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLVEGAHSDAGSQGTDSHTDLPP--------PLERTGGIGDSRSPSFQPDVAS-SRDGMDNETGTESMVSHRRDRAR---RRNREEAARTNGHPRGDRR-RDVGLPPDSASTALSSELESSSFVDSDEDDSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSMTDSTMSLNIITVTLNMERHHFLGICIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRPDPVRPIDPAAWLSHTAALTGALPR--------------------------PQLEEAPLTV-ESDMNTVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCS----NLATLNLNS--GSSGT-SDQDTLAPLPHPAA-PWPLG--QGYPYQYP-GPPPCFPPAYQDPG-FSYGSGSTGSQQSEGSKSSGSTRNT---LRPPACEKERRAAG--------SGD-----SDSESDHTAP----SGVGSS-WRERPADQLSRGS------------------SPRSQASSYAP-GLPPPHPTTKAY---------TVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFF--VDIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGK1-1", "uniprot_id": "A0A8M2BGK1_DANRE", "id": "A0A8M2BGK1-1", "name": "", "aln": "----------MAETKIIYHIDEEETPYLVKLSVAPEKVTLADFKNVLSNRPVNSYKFFFKSMDQDFGVVKEEVSDDNAKLPCFNGRVVSWLVLAESSHTDGMSVCTDSHTEHPP--------PLERTGGIGDSRPPSFHANAVN-SRDGLDTETGSEPVLRHRRERERERTRRRRDDFPRLNGHSKAERVVRDSAMGCDSGS-IMSSELESSSFIDSEDEEDASRLSSSTEQSSSFQLMKRHKRRRRRHKVAKIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKNGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTGSYPQNGTVFLVTDDCMFSAVKHDLILPLFFTEFDELPLTMGKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGGDVVDWLYSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQ----NMATLNLNE--GSSGAGSEQDTLAPLPPPSTNPWPMGG-QPFPYPPF-TAPPAFPPGYSDPC-HSFHSGSAGSHHSEGSRSSSSNPSIGRIQRAVPREKERKSTGSESDSGKRAGGRRVERSASQLSHRSH----ALSSRSHTHSRVPSQHSRTSFSYSHAPFTKYGHTSCALSERSHASSYGPPGLPPPYSLARLTP------KGAVCSGPPGAPPVREMGAIPPELTASRQSFQHAMGNPCEFF--VDIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4ADV8-1", "uniprot_id": "D4ADV8_RAT", "id": "D4ADV8-1", "name": "", "aln": "----------MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQ-RPS--YKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPP--------SMERTGGIGDSRPPSFHPHASGGSQENLDNDTETDSLVSAQRERPRR--RDGPEHAARLNGTTKGER-RREPG-GYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTE--RLDDFHLSI-HSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCG----NMANLSLHDHDGSSGA-SDQDTLAPLPHPGAAPWPMA--FPYQYPPPPHPYNPHPG-FPELG-YSYAGGSASSQHSEGSRSSGSNRS----GSDRRKEKDPKAGDS------KSGG-----SGSESDHTTR-SSLRGPRERAPSERSGPAASEHSHRSHHSLTSSLR------SHHTHPSYG-PPGVPPLYGPPMLMMTPPP-----AAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPTKNFGLFDFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61062-1", "uniprot_id": "DVL3_MOUSE", "id": "Q61062-1", "name": "Segment polarity protein dishevelled homolog DVL-3", "aln": "----------MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQ-RPS--YKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPP--------SMERTGGIGDSRPPSFHPHASGGSQENLDNDTETDSLVSAQRERPRR--RDGPEHAARLNGTTKGER-RREPG-GYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTE--RLDDFHLSI-HSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCG----NMANLSLHDHDGSSGA-SDQDTLAPLPHPGAAPWPMA--FPYQYPPPPHPYNPHPG-FPELG-YSYGGGSASSQHSEGSRSSGSNRS----GSDRRKEKDPKAGDS------KSGG-----SGSESDHTTR-SSLRGPRERAPSERSGPAASEHSHRSHHSLTSSLR------SHHTHPSYG-PPGVPPLYGPPMLMMTPPP-----AAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFF--VDVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92997-1", "uniprot_id": "DVL3_HUMAN", "id": "Q92997-1", "name": "Segment polarity protein dishevelled homolog DVL-3", "aln": "----------MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQ-RPS--YKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPP--------PMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRR--RDGPEHATRLNGTAKGER-RREPG-GYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTE--RLDDFHLSI-HSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCG----NMANLSLHDHDGSSGA-SDQDTLAPLPHPGAAPWPMA--FPYQYPPPPHPYNPHPG-FPELG-YSYGGGSASSQHSEGSRSSGSNRS----GSDRRKEKDPKAGDS------KSGG-----SGSESDHTTR-SSLRGPRERAPSERSGPAASEHSHRSHHSLASSLR------SHHTHPSYG-PPGVPPLYGPPMLMMPPPP-----AAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFF--VDVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14641-1", "uniprot_id": "DVL2_HUMAN", "id": "O14641-1", "name": "Segment polarity protein dishevelled homolog DVL-2", "aln": "MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQ-RPAG-AKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSS-SHENLEPETETESVVSLRRERPRR--RDSSEHGAGGHRTGGPSRLERHLA-GYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH-RRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSG-----SSLPD----GCEGRGLSV-HTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGA-SDQDTLAPLP--GATPWPLLPTFSYQYPAP-HPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDG--GAGRTGRPEERAPES------KSG------SGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTG----GAPNLR------AHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFF--VDVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60838-1", "uniprot_id": "DVL2_MOUSE", "id": "Q60838-1", "name": "Segment polarity protein dishevelled homolog DVL-2", "aln": "MAGSSAGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQ-RPAG-AKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDTPQPEVAPPAHESRTELVPPPPPLPPLPPERTSGIGDSRPPSFHPNVSS-SHENLEPETETESVVSLRRDRPRR--RDSSEHGAGGHRPGGPSRLERHLA-GYESSSTLMTSELESTSLGDSDEDDTMSRFSSSTEQSSASRLLKRH-RRRRKQRPPRMERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGAFPAYPGSSSMSTITSG-----SSLPD----GCEGRGLSV-HMDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGA-SDQDTLAPLP--GATPWPLLPTFSYQYPAP-HPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDG--GAGRTGRPEERAPES------KSG------SGSESELSSRGGSLRRGGEPGGTGDGGPPPSRGSTG----APPNLR------ALPGLHPYGAPSGMALPYNPMMVVMMPPPPPPVSTAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFF--VDVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51140-1", "uniprot_id": "DSH_DROME", "id": "P51140-1", "name": "Segment polarity protein dishevelled", "aln": "---MDADRGGGQETKVIYHIDDETTPYLVKIPIPSAQVTLRDFKLVLN-KQNNNYKYFFKSMDADFGVVKEEIADDSTILPCFNGRVVSWLVSADGTNQ------SDNCSELPT---------SECELGMGLTNRKLQQQQQQHQQQQQQQQQQHQQQQQQQQQQVQPVQLAQQQQQQVLHHQKMMGNPLLQPPPLTYQSAS-VLSSDLDSTSLFGTESELTLDR--DMTDYSSVQRLQVRKKPQRRKKRAPSMSRTSSYSSITDSTMSLNIITVSINMEAVNFLGISIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPGPIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTQALTSHDSIIAD------------------------IAEPIKERLDQNNLEEIVKAMTKPDSGLEIRDRMWLKITIPNAFIGADAVNWVLENVEDVQDRREARRIVSAMLRSNYIKHTVNKLTFSEQCYYVVNEERNPNLLGRGHLHPHQLPHGHGGHALSHADTESITSDIGPLPNPP-IYMPYSATYNPSHGYQP---------IQYGIAERHISSGSSSSDVLTSKD-------------------------------ISASQSDITSV----IHQANQLTIAAHGSNKSSGS------------------SNRG------------------------------------GGGGGGGGGNNTNDQDVS--VFNYVL-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:***:* : ******:.:.. ::** *** **. : *:****** ********: **.: ************* : .: : :: . * *:* :. : . .:: : : : ::: :. : . : :*.* ::*:*:::*: .::.: .* . *: *: :* :: :**::: .*:**:**:*********:**::*** :****.****** ******:********** *********:****::*****:**:***:**::* : *** *.*******.*:. **:** :*::****.**::*: *:*. . : : . :: :.:.* *:****:**********.**.:*.*.*:*: .**.. :**:**: .* :*: . ::*****:******** ..: * :. . * : ..: : * * * . * : : *.** **. . * *: . * * : *. . . : * *. .: ", "identical_positions": 222, "similar_positions": 159, "identity": "28.35%" }, { "cls_id": "homologset.agr.FB:FBgn0000504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A494-1", "uniprot_id": "D4A494_RAT", "id": "D4A494-1", "name": "", "aln": "-------MAANWKCADPHFGKWWLCLEAELAELNGKMLRTP-KCSRCRNHGYLVPVKGHAGKCRWKHCICDKCYLITERQKIMAAQKVLKNQATEE-QGATVGTQGPQL-----------------------------------------------------PPRAPAPAAATATASSSSICPLPRAALGG-AGPGP------------------------------AATCFLERSPQARSPGPSAFQLVPSGRPGPSTFQPGSGGS-------GGLHDRPPAWLPQLRPQAPRPELCCP-DQHLPVR---------------PVPRLPFADYGHPLRFKSDHVVGAGYPEREPFKQCPACIPVPPYQP----------------FPLSEGQDSSSALGVPQQRGFRHVSCGPYHGNSLVS-----------EPARD-----LQPTYCSPPPPP-------LPPPPPQPQQPHFLPPGYLSALHFLPPPPPPPSPPSFSLTILYDTDKEKTNEQGADAPS-EPSQQSTQEESN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9I7-1", "uniprot_id": "DMRTB_MOUSE", "id": "A2A9I7-1", "name": "Doublesex- and mab-3-related transcription factor B1", "aln": "------------------------------------MLRAP-KCSRCRNHGYLVPVKGHTGKCRWKQCICDKCYLITERQKIMAAQKVLRTQAAEE-QVATVGTQGPQL-----------------------------------------------------PPRAPA---AAATALSSSICPLPRAVPGG-VGPGP------------------------------TATCFLERPPQAPSPGPSTFQLGPSGRPGPSTFQPGPGAP-------GGLRDRSSAWLPQLMPQAPRPELCYP-DQHLPVRPVPVPGPV------RPVPRLPFADYGHPLRFKSDHVVGAGNPEREPFKQCPACVPVSPYQS----------------FPLSEGQDSSSALGVPQQRGFRHVSCSPYHRSGLVS-----------EPARD-----LQPTYCSPPPPPPPPPPPPLPAPPPQPQQPHFLPPGYLSALHFLPPPPPPPSPPSFSLT--YDTDKENTNDQDAEAPT-EPSQDSPQEQSN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MA1-1", "uniprot_id": "DMRTB_HUMAN", "id": "Q96MA1-1", "name": "Doublesex- and mab-3-related transcription factor B1", "aln": "--------------------------------MADKMVRTP-KCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQEAALCAQGPKQ-----------------------------------------------------ASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPE---------------------------GRAAACFFEQPPRGRNPGPRALQPVLGGR---SHVEPSERAA-------VAMPSLAG---PPFGAEAAGSGYPGPLDLRRPMR---------------TVPGPLFTDFVRPLNINPDRALGPEYPGGS---------SMHPYCP----------------FPLG---YLDAPPGVPLQQGFRHVSRSQYQGGGLVS-----------EPGGD-----FQPSYYLPPPPPP------LPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQEQSD----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23023-1", "uniprot_id": "DSX_DROME", "id": "P23023-1", "name": "Protein doublesex", "aln": "MVSEENWNSDTMSDSDMIDSKNDVCGGASSSSGSSISPRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQTALRRAQAQDEQRALHMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHGHVLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSHPHSHHHHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAPSSSNAAAATSSNGSSGGGGGGGGGSSGGGAGGGRSSGTSVITSADHHMTTVPTPAQSLEGSCDSSSPSPSSTSGAAILPISVSVNRKNGANVPLGQDVFLDYCQKLLEKFRYPWELMPLMYVILKDADANIEEASRRIEEARVEINRTVAQIYYNYYTPMALVNGAPMYLTYPSIEQGRYGAHFTHLPLTQICPPTPEPLALSRSPSSPSGPSAVHNQKPSRPGSSNGTVHSAASPTMVTTMATTSSTPTLSRRQRSRSATPTTPPPPPPAHSSSNGAYHHGHHLVSSTAAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* :*:****** :.:*** *::: * *:** * ::**::** *..*: ::: * * : * .. *.* . .. ::*: . . . ... :: :. .*:. *. .* * :.. . . . .:. . . * : . . * *: .. :: *. * . : : : * :: . :: . * .**. * . * **.* *. *. * : *. .: : ....*. : * . .. : . : . : *. ..:..*: ", "identical_positions": 56, "similar_positions": 107, "identity": "10.2%" }, { "cls_id": "homologset.agr.FB:FBgn0000520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H8G1-1", "uniprot_id": "ZN430_HUMAN", "id": "Q9H8G1-1", "name": "Zinc finger protein 430", "aln": "---------------------MENLKSGVYPLKEASGCPGADRNLLVYSFYEKGPLTFRDVAIEFSLEEWQCLDTAQQDL-------------YRKVMLENYRNLVFLAGIAVSKPDLITCLEQGKEPWNMKRHAMVDQPPVTYSHFAQDLWPEQGIKDSFQEVILRRYGKCG---------------HEDLQLRTGCKSVDECNLHKECYDELNQCLTTTQSEIFQYDKYVNVFYKFSNPNIQKIRHTGKKPFKCKKCDKSFCM---LLHLTQHKRIHIRENS----------YQCEECGKVFNWFSTLTRHRRIHTGEKPYKCEQCGKAFKQS----STLTTHKIIHTGEKPYRCEECGKTFNRSSHLTTHKRIHTGEKPYRCEECGRAFNRSSHLTTHKIIHTGEKPYKCEECGKAFNQSSTLTTHKIIHAG--EKPYKCEECGKAFYRFSYLTKHKIIHTGEKFYKCEECGKGFNWSSTLTKHKRIHTGEKPYKCEQCGKAFNESSNLTAHKIIHTGEKPYKCEECGKAFNRSPKLTAHKVIHSGEKPYKCEECGKAFNQFSNLTKHKITHIGDTSYKYLECDKAFSQSSTLTKHKVIHTGEKPYNCEEYGKAFNQSSNLIEQSNSYWRETLQM-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TF32-1", "uniprot_id": "ZN431_HUMAN", "id": "Q8TF32-1", "name": "Zinc finger protein 431", "aln": "---------------------MDDLKYGVYPLKEASGCPGAERNLLVYSYFEKETLTFRDVAIEFSLEEWECLNPAQQNL-------------YMNVMLENYKNLVFLG-VAVSKQDPVTCLEQEKEPWNMKRHEMVDEPPAMCSYFTKDLWPEQDIKDSFQQVILRRYGKCE---------------HENLQLRKGSASVDEYKVHKEGYNELNQCLTTTQSKIFPCDKYVKVFHKFLNANRHKTRHTGKKPFKCKKCGKSFCM---LLHLSQHKRIHIRENS----------YQCEECGKAFKWFSTLTRHKRIHTGEKPFKCEECGKAFKQS----STLTTHKIIHTGEKPYRCEECGKAFNRSSHLTTHKIIHTGEKPYKCEECGKAFNQSSTLSTHKFIHAGEKPYKCEECDKAFNRFSYLTKHKIIHTG--EKSYKCEECGKGFNWSSTLTKHKRIHTGEKPYKCEVCGKAFNESSNLTTHKMIHTGEKPYKCEECGKAFNRSPQLTAHKIIHTGEKPYKCEECGKAFSQSSILTTHKRIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKSYKCEECGKAFNQSSTLTKHRKIHTRQKPYNCEECDNTFNQSSNLIKQNNSYWRETLQMSRMWESL----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9P255-1", "uniprot_id": "ZN492_HUMAN", "id": "Q9P255-1", "name": "Zinc finger protein 492", "aln": "-------------------------------------------------------------------------------------------------MLENYRNLVFVG-IAASKPDLITCLEQGKEPWNVKRHEMVAEPPVVCSYFARDLWPKQGKKNYFQKVILRRYKKCG---------------CENLQLRKYCKSMDECKVHKECYNGLNQCLTTTQNKIFQCDKYVKVFHKFSNSNRHTIRHTGKKSFKCKECEKSFCM---LSHLAQHKRIHSGEKP----------YKCKECGKAYNETSNLSTHKRIHTGKKPYKCEECGKAFNRL----SHLTTHKIIHTGKKPYKCEECGKAFNQSANLTTHKRIHTGEKPYKCEECGRAFSQSSTLTAHKIIHAGEKPYKCEECGKAFSQSSTLTTHKIIHTG--EKFYKCEECGKAFSQLSHLTTHKRIHSGEKPYKCEECGKAFKQSSTLTTHKRIHAGEKFYKCEVCSKAFSRFSHLTTHKRIHTGEKPYKCEECGKAFNLSSQLTTHKIIHTGEKPYKCEECGKAFNQSSTLSKHKVIHTGEKPYKYEECGKAFNQSSHLTTHKMIHTGEKPYKCEECGKAFNNSSILNRHKMIHTGEKLYKPESCNNACDNIAKISKYKRNCAGEK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NK75-1", "uniprot_id": "ZNF98_HUMAN", "id": "A6NK75-1", "name": "Zinc finger protein 98", "aln": "-------------------------------------MPGPLG------SLEMGVLTFRDVALEFSLEEWQCLDTAQQNL-------------YRNVMLENYRNLVFVG-IAASKPDLITCLEQGKEPWNVKRHEMVTEPPVVYSYFAQDLWPKQGKKNYFQKVILRTYKKCG---------------RENLQLRKYCKSMDECKVHKECYNGLNQCLTTTQNKIFQYDKYVKVFHKFSNSNRHKIGHTGKKSFKCKECEKSFCM---LSHLAQHKRIHSGEKP----------YKCKECGKAYNEASNLSTHKRIHTGKKPYKCEECGKAFNRL----SHLTTHKIIHTGKKPYKCEECGKAFNQSANLTTHKRIHTGEKPYKCEECGRAFSQSSTLTAHKIIHAGEKPYKCEECGKAFSQSSTLTTHKIIHTG--EKFYKCEECGKAFSRLSHLTTHKRIHSGEKPYKCEECGKAFKQSSTLTTHKRIHAGEKFYKCEVCSKAFSRFSHLTTHKRIHTGEKPYKCEECGKAFNLSSQLTTHKIIHTGEKPYKCEECGKAFNQSSTLSKHKVIHTGEKPYKCEECGKAFNQSSHLTTHKMIHTGEKPYKCEECGKAFNNSSILNRHKMIHTGEKLYKPESCNNACDNIAKISKYKRNCAGEK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZN08-1", "uniprot_id": "ZNF66_HUMAN", "id": "Q6ZN08-1", "name": "Zinc finger protein 66", "aln": "----------------------------------------------------MGPLQFRDVAIEFSLEEWHCLDMAQRNL-------------YRDVMLENYRNLVFLG-IVVSKPDLITHLEQGKKPSTMQRHEMVANPSVLCSHFNQDLWPEQSIKDSFQKLILRRHKKCG---------------HDNLQLKKGCESVDKCKVHKRGYNGLNQCLTTTQSKMFQCDKHGKVFHQFSNTNRHKIRHTGKNPCKFTECGKAFNR---SSTFTTHKKIHTGEKP----------YKCIECGKAFNRSSHLTTHKIIHTGEKRYKCEDCGKAFNRS----SNLTTHKKIHTGEKPYKCEECGKAFKRSSILTTHKRIHTGEKPYKCEECGKVFKYLSSLSTHKIIHTGEKPYKCEECGKAFNWSSHLTTHKRIHTG--EKPYKCEECGKGFKYSSTLTKHKIIHTGEKPYKCEECGEAFKYSCSLTAHKIIHTGKKPYKCEECGKVFKHSSPLSKHKRIHTGEKPYKCEECGKAFSRSSILTTHKIIHTGEKPYECEDCGKAFNRSSNLTKHKKIHTGEKPYKCEECGKAFKCSSILTTHKRIHTADKPYKCEECGKDFKYSSTLTRHKKIHTGGKPHKCNKCGKAFISSSNLSRHEIIHMGGNPYKCENVAKP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4V9-1", "uniprot_id": "Q9W4V9_DROME", "id": "Q9W4V9-1", "name": "", "aln": "---------------------MMNSKIAEVVVLNCRTCT-RACKLHKPLQEEIDLGSEGSTTLASMLNYCTGLSFEPQDG-------------AAMPQHICLHCLQLLEQAFNFKRMVIDSDELLRLGLDEARCSSFHESQTHSPNQSQQHDQQQQAFDSTEEYVMIEMLNEE---------------QENVANLDEELAEEDRRIFAMTVDEEEEFLTEEVDQDDELSEEEHQLAQSGDQQEEHITMESVHEFQPAEVEYVTIKNEFETIVTEEDEFEVMNDSGAHDAILDCQMIVIPAEGAIDEVIGEETLELEGDGREEHLLPEAEDVCEDEDFLEESLDSAPPTAGEALPYVCTVCQKAFRQQCRLNQHMRSHVDEKQYECEECGKRLKHLRNYKEHMLTHTNVKPHQCSICGRFYRTTSSLAVHKRTHAE--KKPYNCDQCGRGYAAFDHLRRHKLTHTGERPYACDLCDKAYYDSSSLRQHKISHTGKKAFTCEICGVGLSQKSGYKKHMMVHSGVKAHKCDVCGHAFTFTSNLNAHVRLHSGEKPFKCEVCVKAFPTKKRLASHMRVHNKESPVTATVAVQSINPPSRQAGAEGATGGGATGGSPTGGGATGGSATNLHITEVHEQPVSTSKVVMVL-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8N7TAL0-1", "uniprot_id": "A0A8N7TAL0_DANRE", "id": "A0A8N7TAL0-1", "name": "", "aln": "MLIVEKTADHPSVEFSIVEDVALHCTFLMDRLNEQRLFQPDLCDVDIVLLHHHKSFQAHKGILAAFSPFFHSLFASSKDLRRVELSLDALKPQGLQQILNFIYTSRLLVSGCNAQDVLRAATVLQMSNIATSCSELISRGSVEISVKDQQNKPEGNWSDSVKDIKQEKDTTCARICGGKSEGNPYSVQVADLQSVQGGICKVEGKEPRNPEDPDSFNGEQIIVELNLNNQTLNVSKGLDGSSAAQSPSGQQLSGKEKSSDGTFEESRNNVTLEEEEEEEDGEQSEDEDDDDDVRLEGTSEDEGESVFLSEMKSRASAPLVSKRSCARARQETDRD------PSEERLDQDGFESFSCLRCPKTFNNRWYLEKHMNVTHN-RMCVCEKCGKRFLLDSELLLHQQTDC-EKSIQCLTCGKAFRKLWSLHEHNKIVHGYAEKKYTCEICEKKFYTMAHVRKHMVAHTKEMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFQCEVCSERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPYICEICGKSFTSRPNMKRHRRTHTGEKPYPCEACGQRFRFSNMLKTHREKCLQVRNPLLLDSSTIVNHTNQDLPGGMETLGDVSPHLHGMVSFPSSVLHSVEGAPSNSHLRSVMPLFSTGRTDSRIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . . . . :: : : :. . :: . . . : . : .: : . . : . . ... . :.. . . . . . . .: * * *:*.. * * . : **:**: : * . *. :* *.: : * *: :* *.*: * : : : * *: * : *: *.:.: * .* *. *:*:* : ** *. :. * :* * * . *: **: *. . : * *:****: ** * *:* : * * :.. . : : .. . . : ", "identical_positions": 55, "similar_positions": 103, "identity": "8.1%" }, { "cls_id": "homologset.agr.FB:FBgn0000524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RA58-1", "uniprot_id": "M0RA58_RAT", "id": "M0RA58-1", "name": "E3 ubiquitin-protein ligase", "aln": "-----MSRPG----------------QGVMVPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR---------GSVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMR-----PVRRNFYDPSSAPGKGIVWEWE----NDGGAWTAYDMDICITIQNAYEKQHPWLDLS--SLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPK-SQSWPVGASS------------------------------------------------GQPCSCQQCLLVNSTRA--------------------------------------------ASNAILASQRRKAPIA------------------PAAPPAPPP-------------------------PPPPLPPGGPPSALVVRPSATFAGAALWAAPAAGPTEPAPPPGVPP---RSPSAPNGAPTPGQNNLSRPGPQRSTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNP-EDVVRRYMQKVK---------NPPDEDCTICMERLVTASGYEGVLRN-KSVRPELVG------RLGRCGHMYHLLCLVAMYSNGNKVGHKDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFADTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAMAKA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61010-1", "uniprot_id": "DTX1_MOUSE", "id": "Q61010-1", "name": "E3 ubiquitin-protein ligase DTX1", "aln": "-----MSRPG----------------QGVMVPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR---------GSVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMR-----PVRRNFYDPSSAPGKGIVWEWE----NDGGAWTAYDMDICITIQNAYEKQHPWLDLS--SLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPK-SQSWPVGASS------------------------------------------------GQPCSCQQCLLVNSTRA--------------------------------------------ASNAILASQRRKAPIA------------------PAAPPAPPP-------------------------PPPPLPPGGPPGALVVRPSATFAGAALWAAPATGPTEPAPPPGVPP---RSPSAPNGAPTPGQNNLSRPGPQRSTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNP-EDVVRRYMQKVK---------NPPDEDCTICMERLVTASGYEGVLRN-KSVRPELVG------RLGRCGHMYHLLCLVAMYSNGN----KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFADTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAMAKA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y01-1", "uniprot_id": "DTX1_HUMAN", "id": "Q86Y01-1", "name": "E3 ubiquitin-protein ligase DTX1", "aln": "-----MSRPG----------------HGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR---------GSVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMR-----PVRRNFYDPSSAPGKGIVWEWE----NDGGAWTAYDMDICITIQNAYEKQHPWLDLS--SLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPK-SQSWPVGASS------------------------------------------------GQPCSCQQCLLVNSTRA--------------------------------------------ASNAILASQRRK------------------------APPAPPL-------------------------PPPP-PPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPP---RSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNP-EDVVRRYMQKVK---------NPPDEDCTICMERLVTASGYEGVLRH-KGVRPELVG------RLGRCGHMYHLLCLVAMYSNGN----KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LQY8-1", "uniprot_id": "A0ABK0LQY8_RAT", "id": "A0ABK0LQY8-1", "name": "E3 ubiquitin-protein ligase", "aln": "-----------------------------MLLAS----------AVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRA-------GGSVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLR-----PVRRNYYDPSSAPGKGVVWEWE----NDNGSWTPYDMEVGITIQHAYEKQHPWIDLT--SIGFSYIIDFSTMGQINRQTQRQRRVRRRLDLIYPMVTGTVPK-AQSWPVSPGP-------------------------------------------ATPSPAPPCSCPQCVLVMSVKA---------------------------------------AVVHGSTGPLHPPAARKNIAP---------------SGVGKLPQPPGP------------------------GAKPLDTTGTIRGPGKTAPSQVIRRQVSNTPAGVTVGSPASPQGSNR---KTG-------RVALTTLNRSNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTP-EEVLKKYLQKVR---------HPPEEDCTICMERLTAPSGYKGP--Q-PTVKPDLVG------KLSKCGHIYHIYCLVAMYNNGN----KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTSQEKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDK8-1", "uniprot_id": "DTX4_MOUSE", "id": "Q6PDK8-1", "name": "E3 ubiquitin-protein ligase DTX4", "aln": "-----------------------------MLLAS----------AVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRA-------GGSVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLR-----PVRRNYYDPSSAPGKGVVWEWE----NDNGSWTPYDMEVGITIQYAYEKQHPWIDLT--SIGFSYIIDFSTMGQINRQTQRQRRVRRRLDLIYPMVTGTMPK-TQSWPVSPGP-------------------------------------------ATSSPAPPCSCPQCVLVMSVKA---------------------------------------AVVHGGTG---PPAVRKNMAL---------------SGVGKLPQPPGP------------------------GAKPLDTTGTIRGPGKTAPSQVIRRQVSNAPAGATVGSPASPQGSNR---KTG-------RVALATLNRSNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTP-EEVLKKYLQKVR---------HPPEEDCTICMERLTAPSGYKGP--Q-PTVKPDLVG------KLSRCGHIYHIYCLVAMYNNGN----KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTSHEKD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2E6-1", "uniprot_id": "DTX4_HUMAN", "id": "Q9Y2E6-1", "name": "E3 ubiquitin-protein ligase DTX4", "aln": "-----------------------------MLLAS----------AVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRA-------GGSVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLR-----PVRRNYYDPSSAPGKGVVWEWE----NDNGSWTPYDMEVGITIQHAYEKQHPWIDLT--SIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPK-AQSWPVSPGP-------------------------------------------ATSPPMSPCSCPQCVLVMSVKA---------------------------------------AVVNGSTGPLQLPVTRKNMPP---------------PGVVKLPPLPGS------------------------GAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNS---KTG-------RVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTP-EEVLKKYLQKVR---------HPPDEDCTICMERLTAPSGYKGP--Q-PTVKPDLVG------KLSRCGHVYHIYCLVAMYNNGN----KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RDA3-1", "uniprot_id": "A0A8M1RDA3_DANRE", "id": "A0A8M1RDA3-1", "name": "E3 ubiquitin-protein ligase", "aln": "--------------------------MDTMLLAS----------AVVVWEWLNEHGRWRPYSPAVSHHIEEVIRSDPR--------GGSVVLGQADSRLSPYIIDLQSMHQFRQDTGTLR-----PVRRSFYDPTSAPGQGWIWEWE----NDTGSWITYDMEVSIALQAAWDRHQPWLDMT--SMGFCYFVDFKTMIQFNRQTQRQRRIQRRSDMVYPLVSGPLPKNSQAWGSALGAGGIAKGVISGAGSTGALLGVGVSGSTLSRKGSAVYPSGTLSVSSLAPLGQPCACQQCMLVLSVKSNGTSSQTLGRATKPNSPKSNFGTLSSSSASMSVLNSYSQTLPHGTSLKSSPSEEAKNFDQSLSLLTSGTASLSVSSSRPRLPSLPPPPN------------------LPSLNQQPPSASGSS-SSASFVPTAVLVNTSTNPTSSTVLTSSTTTLPSQR---STACAAPLPPRASLAGLSRPALQRIAMAQSRALIASGVPTVPVKNLNGSSPVQPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSDIRPIPGIGHCCRKTTKKQARKGKTP-EEVVKRYLQKVR---------SPPEEDCTICMEALGGPSGYKGPGVA-SVSRAESVG------RLAQCGHLYHLQCLVAMYNNGN----KDGSLQCPTCKTIYGVKTGNQPAGKMEYHVIPHSLPGHPDCKTIRIIYNIPPGIQGPEHPNPAKPFTARGFPRHCYLPDNEKGRKVLRLLLVAWDRRLIFSVGTSSTTGESDTVIWNEIHHKTEFGSNLTGHGYPDSGYLDHVLEELKAQGITEDEEQLL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V658-1", "uniprot_id": "G3V658_RAT", "id": "G3V658-1", "name": "E3 ubiquitin-protein ligase", "aln": "-----MAMAP----------------SSSLPQVYPS------HVVVAVWEWQDGLGIWHPYSATVCSFIEQQFIRQRGQHFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMR-----SVRRHLFSQNSAPGQGIVWEWL----GDDGSWIAYEARICDYLEQQVARGIQVVDLA--PLGYNYTVNYATLTQTNKTSSFCRSVRRQVGPVYPVTSDIAVP--------------------------------------------------------RQMGLICFCQQCLHGSGTG-------------------------------------------------PVSGRYRHSMTN-----------------LPAYPAPQAP------------------------HRTATVSGAHQAFAPYNKPSLSGARSAPRLNTTSPWGATPPVPGNQSLLHSSLSHLGPQLLPSGPSTSSGTSASFPSGPSSSSPGSAPTTVPVQ-MPKPSRVQQALAGMTSVLS-AIGLPVCLSRAP--RPTGPPASRPTSKSHSSVKRLRKMSVKEGAPKPEPE--QVIRKYTEELK---------VAPEEDCIICMEKLSVASGYSDVTDS-KALGPMVVG------RLTKCSHAFHLLCLLAMYCNGN----KDGSLQCPSCKTIYGEKTGTQPWGKMEVFRFHMSLPGHEDCGTILIVYNIPHGIQGPEHPSPGKPFTARGFPRQCYLPDSPQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3P2-1", "uniprot_id": "DTX2_MOUSE", "id": "Q8R3P2-1", "name": "Probable E3 ubiquitin-protein ligase DTX2", "aln": "-----MAMAP----------------SSSLPQVYPS------HVVVAVWEWQDGLGIWHPYSATVCSFIEQHFVRQRGQHFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQNTGTMR-----SVRRHLFSQNSAPGQGIVWEWL----GDDGSWVAYEARICDYLEQQVARGIQVVDLA--PLGYNYTVNYATLTQTNKTSSFCRSVRRQVGPVYPVTSDIAVP--------------------------------------------------------RQMGLICFCQQCLHGSGTG-------------------------------------------------PVSGRYRHSMTN-----------------LPAYPAPQAP------------------------HRTTTVSGAHQAFAPYNKPSLSGARSAPRLNTTNPWAAAPPVAGNQSLFHSSLSHLGPQLLPSGPSTSSGASASFPSGPSSSSPGSAPTTVPVQ-MPKASRVQQALAGMTSVLS-AIGLPVCLSRAP--RPTGPPASRPASKSHSSVKRLRKMSVKEGAPKPEPE--QVIRKYTEELK---------VAPEEDCIICMEKLAVASGYSDMTDS-KALGPMVVG------RLTKCSHAFHLLCLLAMYCNGN----KDGSLQCPSCKTIYGEKTGTQPWGKMEVFRFQMSLPGHEDCGTILIVYNIPHGIQGPEHPSPGKPFTARGFPRQCYLPDSPQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNVTGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UW9-1", "uniprot_id": "DTX2_HUMAN", "id": "Q86UW9-1", "name": "Probable E3 ubiquitin-protein ligase DTX2", "aln": "-----MAMAP----------------SPSLVQVYTS------PAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMR-----AVRRHLFPQHSAPGRGVVWEWL----SDDGSWTAYEASVCDYLEQQVARGNQLVDLA--PLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPP--------------------------------------------------------GHTGVACSCHQCLSGSRTG-------------------------------------------------PVSGRYRHSMTN-----------------LPAYPVPQHPP-----------------------HRTASVFGTHQAFAPYNKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSS-PGSVPATVPMQ-MPKPSRVQQALAGMTSVLMSAIGLPVCLSRAP--QPTSPPASRLASKSHGSVKRLRKMSVKGATPKPEPEPEQVIKNYTEELK---------VPPDEDCIICMEKLSTASGYSDVTDS-KAIGSLAVG------HLTKCSHAFHLLCLLAMYCNGN----KDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TWU4-1", "uniprot_id": "A0AB32TWU4_DANRE", "id": "A0AB32TWU4-1", "name": "E3 ubiquitin-protein ligase", "aln": "-----MATGSSFPSGGSGTRNGPSFASPSTSSVTSSGVPGQAQPMAVVWEWQDDLGFWRPYTGQVSSYIEQCLQHQRG----AAVAGSSICLAQADPSLSSYIIDIPNLKQFRQDTGKMR-----AVRRSLFPQSSALGSGVLWEWS----NDEGGWTAYEIRTSILLEHSYQAGQATADLS--PHGYNYIVDLGALEQVNKATSYRRRVRRQGNVPYPLASGSVI----------------------------------------------------------HSGPACTCHQCVTNSSTAG------------------------------------------------PMLSRSRHSFSAG----------------QAIRPSLQTQH-----------------------GRLPVTSSSSSAYSPYPRRPLS----MGSLLWNGPWSTPPSVP-----------------HPTGP----------PQNFGHHSNGLSIPTIPLH-MNGSSSVNSALAGMASILMSAAGLGVRLMTAP--FSQ-RDSSMPTKGQASSVKRAKRQSRTAPAQK--PE--EVIKKYMEEVP---------VVPDEDCIICMERLSCPSGYEVPAECSQSLQPSTVG------KLTKCAHTFHMLCMLAMYNNGT----KDGSLQCPSCKTIYGEKTGTQPKGKMEIYSIPQSLPGHPDCGTIQIIYNIPPGIQGPEHPNPGQPYTCRGFPRFCFLPDNDKGRKVLELLKVAWTRRLIFTVGTSSTTGEPDTVIWNEIHHKTEMMSNVSGHGYPDPNYLDNVLSELASQGVTEDCLKRDAQGSAM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23985-1", "uniprot_id": "DTX_DROME", "id": "Q23985-1", "name": "Protein deltex", "aln": "MASSAGSAASGSVVPGGGGSAASSCATMALSTAGSGGPPVNHAHAVCVWEFE-SRGKWLPYSPAVSQHLERAHAKKLTR----------VMLSDADPSLEQYYVNVRTMTQESEAETAGSGLLTIGVRRMFYAPSSPAGKGTKWEWSGGSADSNNDWRPYNMHVQCIIEDAWARGEQTLDLCNTHIGLPYTINFCNLTQLRQPSGPMRSIRRTQQAPYPLVKLTPQQANQLKSNSASVSSQYNTLPKLG-------------------------------DTKSLHRVPMTRQQHPLPTSHQVQ-------------------------------------QQQHQHQHQQQQQQQHHHQHQQQQHQQQQQHQMQHHQIHHQTAPRKPPKKHSEISTTNLRQILNNLNIFSSSTKHQSNMSTAASASSSSSSASLHHANHLSHAHFSHAKNMLTASMNSHHSRCSEGSLQSQRSSRMGSHRSRSRTRTSDTDTNSVKSHRRRPSVDTVSTYLSHESKESLRSRNFAISVNDLLDCSLGSDEVFVPSLPPSSLGERAPVPPPLPLHPRQQQQQQQQQQQLQMQQQQQAQQQQQQSIAGSIVGVDPASDMISRFVKVVEPPLWPNAQPCPMCMEELVHSAQNPAISLSRCQHLMHLQCLNGMIIAQQNEMNKNLFIECPVCGIVYGEKVGNQPIGSMSWSIISKNLPGHEGQNTIQIVYDIASGLQTEEHPHPGRAFFAVGFPRICYLPDCPLGRKVLRFLKIAFDRRLLFSIGRSVTTGREDVVIWNSVDHKTQFN------MFPDPTYLQRTMQQLVHLGVTD------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ***: . * **: *. .:* : *.:.*. * * ::: . * : *** : *. * * *** .. . * .*: :: *: * * : * .: : * ::* **:. * : * . . . .. .:: . : :* . : * * * : : :. :: * .* : : .. : . * :* * *: *: .* *: ::** * :** *.*.** *.*. : .***. . ** *:*.*. *:* *** *.: : . **** *:**: *****.:* *: ***:*::* * ***. *.*:**.:.***:: :**. **:..: :* *::: ", "identical_positions": 108, "similar_positions": 113, "identity": "12.93%" }, { "cls_id": "homologset.agr.FB:FBgn0000527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07702-1", "uniprot_id": "LYS2_YEAST", "id": "P07702-1", "name": "L-2-aminoadipate reductase", "aln": "MTNEKVWIEKLDNPTLSVLPHDFLRPQQEPYTKQATYSLQLPQLDVPHDSFSNKYAVALSVWAALIYRVTGDDDIVLYIANNKILRFNIQPTWSFNELYSTINNELNKLNSIEANFSFDELAEKIQSCQDLERTPQLFRLAFLENQDFKLDEFKHHLVDFALNLDTSNNAHVLNLIYNSLLYSNERVTIVADQFTQYLTAALSDPSNCITKISLITASSKDSLPDPTKNLGWCDFVGCIHDIFQDNAEAFPERTCVVETPTLNSDKSRSFTYRDINRTSNIVAHYLIKTGIKRGDVVMIYSSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPRGLIVIRAAGQLDQLVEDYINDELEIVSRINSIAIQENGTIEGGKLDNGEDVLAPYDHYKDTRTGVVVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFNWMSKRFNLTENDKFTMLS-GIAHDPIQRDMFTPLFLGAQLYVPTQDDIGTPGRLAEWMSKYGCTVTHLTPAMGQLLTAQATTP--------FPKLHHAFFVGDILTKRDCLRLQTLAEN--CRIVNMYGTTETQRAVSYFEVKSKNDDPNFLKKLKDVMPAGKGMLNVQLLVVNRNDRTQICGIGEIGEIYVRAGGLAEGYRGLPELNKEKFVNNWFVEKDHWNYLDKDNGEPWRQFWLGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTHISQHPLVRENITLVRKNADNEPTLITFMVPRFDKPDDLSKFQSDVPKEVETDPIVKGLIGYHLLSKDIRTFLKKRLASYAMPSLIVVMDKLPLNPNGKVDKPKLQFPTPKQLN------LVAENTVSETDDSQFTNVEREVRDLWLSILPTKPASVSPDDSFFDLGGHSILATKMIFTLKKKLQVDLPLGTIFKYPTIKAFAAEIDRIKSSGGSSQGEVVENVTANYAEDAKKLVETLPSSYPSREYFVEPNSAEGKTTINVFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQKAGITYGTWNEKFASNIKVVLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAKLRDPNVISTINVMSLAAVGKPKFFDFVSSTSTLDTEYYFNLSDKLVSEGKPGILESDDLMNSASGLTGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASANGSSNTDDFLLRFLKGSVQLGKIPDIENSVNMVPVDHVARVVVATSLNPPKENELAVAQVTGHPRILFKDYLYTLHDYGYDVEIESYSKWKKSLEASVIDRNEENALYPLLHMVLDNLPESTKAPELDDRNAVASLKKDTAWTGVDWSNGIGVTPEEVGIYIAFLNKVGFLPPPTHNDKLPLPSIELTQAQISLVASGAGARGSSAAA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDC6-1", "uniprot_id": "EBO_DROME", "id": "Q9VDC6-1", "name": "Beta-alanyl-bioamine nonribosomal peptide synthetase ebony", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSLPQLSIVKGLQQDFVPRALHR-------------------IFEEQQLRHADKVALIYQPSTTGQGMAPSQSSYRQMNERANRAARLLVAETHGR--------FLQPNSDGDFIVAVCMQPSEGLVTTLLAIWKAGGAYLPIDPSFPANRIHHILLEAKP--TLVIRDD--------DIDAGRFQGTPTLSTTELYAKSLQLAGSNLLSEEMLR-------------GGNDHIAIVLYTSGSTGVPKGVRLPHESILNRLQWQWATFPYTANEAVSVFKTALTFVDSIAELWGPLMCGLAILVVPKAVTKDPQRLVALLERYKIRRLVLVPTLLRSLLMYLKMEGGGAAQKLLYNLQIWVCSGEPLSVSLASSFFDYFDEGVHRLYNFYGSTEVLGDVTYFACESKKQ-----LSLYDNVPIGIPLSNTVVYLLDADYRPVKN--GEIGEIFASGLNLAAGY--VNGRDPERFLENPLAVEKKY-------------------ARLYRTGDYG-SLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKAIVLCYHAGQVDQAILAFVKLRDDAP--------------------------MVTEMQMEARLKDKLADYMTP-QVVILEHVPLLVNGKVDRQALLKTYETANNNEGDSSIVLDFDYSQVPEDLKLTARDLFETVGGVIGRSTRATLAPHSNFYELGGN-------------------SLNSIFTVTLLREKGYNIGISEFIAAKNLGEIIEKMAAN--HDAVQLEEESLNACPHLKMEAVPLRLEHR--QEVIDIIVASFYNKADLEQWLKPG--------------------VLRTDYSDILNDIWNVLVERDLSFVVYDTN----------------------------------------------------------------TDRIIGTALNFDARNEPEVDIKSKLLIVFEFLEFCEGP---------------------------IRDNYLPKG------------LNQILHSFMMGTAEKLNPRENIACMHFMEHEVLRVAREKQFAG------------------IFTTNTSPLTQQLADVYHYKTLLNFQVN-----------------------------------------EYVHSDGSRPFGDAPDEQ-RAIVHWKEVGK--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :::** . :::. ** ::* .* *. *:: . *.::. : . :* :. . .* :::.. . . :* : . . .*:. ::.: ***.:: ***::*. * * *** :*** * ..:: .. :.: : :. .*. .*::* * * . : :**** *:**** * *: ::* * * *: .:::. .::. ::: **: * : * .: * **. :.:* *.*:: : * . : :*: . *: *: . : :: *: *:**:**. *:** :**:: .* * :* * : *. : ::: : *. ******:. . .** ** : : *:*::* :. :.:: ******* * * **. **:*.******.*::*.*::.:::: *** : *.* : .: : ::::*: * * * : . ::.: **.:**.* * :*:::::** *****: * . . * :* : *:. :. ... .. : * :. *:::*...*::***: .*.:**. . :: . :*. : .... **::*:::** .** :* * .: * : . * * : :*: *:.* .. * : * . . * : :.* . ** . ::..*: * . : :.* *: :: : *. :* :::: ..* :* .*:. . *. : *. :*. .:: *:. :..: : *: .: : . ::* : :: . ::*. *: .* :. * *. :* :*:* *.. ::** ", "identical_positions": 202, "similar_positions": 319, "identity": "14.34%" }, { "cls_id": "homologset.agr.FB:FBgn0000529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5F6-1", "uniprot_id": "D4A5F6_RAT", "id": "D4A5F6-1", "name": "Brain-specific homeobox protein homolog", "aln": "---------------MNLNFTSPLHPASSQRP---------TSFFIEDILLHKPKPLR-------------------------------------------------------------EVAPDHFASSLASRVPLLDYGYPLMPTPTLLTPHTHHPLHKGEHHHPYFLATSGMPVPALFPHPQHAELPG-------------------------------------------------------------------------------KHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAADGPE-SPEGSPRAPEGAP-ADARLSLPAG----------------------AFVLTEPEDEVDIGDEGELSSGPHVL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810B3-1", "uniprot_id": "BSH_MOUSE", "id": "Q810B3-1", "name": "Brain-specific homeobox protein homolog", "aln": "---------------MNLNFTSPLHPASSQRP---------TSFFIEDILLHKPKPLR-------------------------------------------------------------EVAPDHFASSLASRVPLLDYGYPLMPTPTLLTPHAHHPLHKGDHHHPYFLTTSGMPVPALFPHPQHAELPG-------------------------------------------------------------------------------KHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAADGPE-SPEGSPRAPEGAP-ADARLSLPAG----------------------AFVLTEPEDEVDIGDEGELSSGPHVL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3C1V8-1", "uniprot_id": "BSH_HUMAN", "id": "Q3C1V8-1", "name": "Brain-specific homeobox protein homolog", "aln": "---------------MNLNFTSPLHPASSQRP---------TSFFIEDILLHKPKPLR-------------------------------------------------------------EVAPDHFASSLASRVPLLDYGYPLMPTPTLLAPHAHHPLHKGDHHHPYFLTTSGMPVPALFPHPQHAELPG-------------------------------------------------------------------------------KHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAPDGPE-SPEGSPRGSEAATAAEARLSLPAG----------------------PFVLTEPEDEVDIGDEGELGSGPHVL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6R3Q6-1", "uniprot_id": "BSH_DANRE", "id": "Q6R3Q6-1", "name": "Brain-specific homeobox protein homolog", "aln": "---------------MNLNYTSPVPQMPTQRS---------TSFFIEDILLHKPKPLR-------------------------------------------------------------EVFPSPFSNSIASRMPLLEYGYPLMPTP-ILAPHPHHPLHK-PEHHPYFFT-SGMQMPALFQH--HPELPG-------------------------------------------------------------------------------KHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKTQDDQKTPNDVDRSLENTSESEMHEKNTDGKNGMSPD----------------------RYTLDDNEDDVDIEDD--ICSPEHLL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04787-1", "uniprot_id": "BSH_DROME", "id": "Q04787-1", "name": "Brain-specific homeobox protein", "aln": "MAMLNEASLSPADAHAHANATTPTHSKAAAMASATTMLTTKTPFSIEHILFQNLNSASNNNNSSDTNGIAANTNNYAPKSSRNAVKSARSAFAHDNNPHKHPSQHSHPPQSHPPASASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRSEPGKQPGEATSSSGDSKHGKLNPGSVGGTPTQPTSEQQLQMCLMQQGYSTDDYSDLEADSGDEDNSSDVDIVGDAKLYQLT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *:* .: . *.* **.**::: :. .. . :.. ** . :** .: .** * . * .: . : .. *.: :. * :*************.********** ****************.**********************: :: :. : . . . : : .. : : .* .: * .:: ", "identical_positions": 82, "similar_positions": 58, "identity": "19.11%" }, { "cls_id": "homologset.agr.FB:FBgn0000533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1N826-1", "uniprot_id": "A0A8M1N826_DANRE", "id": "A0A8M1N826-1", "name": "", "aln": "-MKMNTALTVVGALLVNIAGSLCQLNVCGRAP-------------------------------------------------------------------------------------------LNTKIVGGQNAGAGSWPWQVSLQSPTYGG---HFCGGSLINKDWVLSAAHCFQDSLGTVKVKLG------------------LQSQSGSNPYQITKTVVQVINHPNYNNPSND--NDIALVKLDSSVTFNDYIEPVCLAAAGNTYAA---GTLSWVTGWGKLSSAANQIPDILQEVEIPIVSNSDCKRAYPG---EITSNMICAGLLDQGGKDSCQGDSGGPMVSRNG----SQWIQSGIVSFG-RGCAEPGYPGVYARVSQYQDWITSSTGSSNPPGFVEFHSSGFRSTSNLFLLSISLTLSIIPFASVLSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13582-1", "uniprot_id": "EAST_DROME", "id": "P13582-1", "name": "Serine protease ea", "aln": "MLKPSIICLFLGILAKSSAGQFYFPNEAAQVPNYGRCITPNRERALCIHLEDCKYLYGLLTTTPLRDTDRLYLSRSQCGYTNGKVLICCPDRYRESSSETTPPPKPNVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLS--ASNLKLKAAVEGSRMDECQNVYSSQDILLEDTQMCAGGKE--GVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . .:* * . **.: * ..:.* *..:* ** :: ..:** . :: .. * *.******.. :*::*:**.:.. ... :*. ::. ... * :: .* :.* **:* .*:: *****::* ..* :.*::.*:**. * :* * *:**** .. : .:: :. : .:*:..*.. : .. :*** : * ***:******::. : : :: :*:**** *. .*:****: *.:* *** .: * ", "identical_positions": 84, "similar_positions": 107, "identity": "19.27%" }, { "cls_id": "homologset.agr.FB:FBgn0000535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPI9-1", "uniprot_id": "KCNH5_RAT", "id": "Q9EPI9-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH5", "aln": "--MPGGKRGLVAPQNTFLENIVR---------RSSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKSS--TCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKN-----------------RTPVWFYMQIAPIRNEHEKVVLFLCTFKDITLFKQPIEDDSTK---GWTKFARLTRALTNSRSVLQQLTPMNKTETV-HKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLALSIGTPYRYNTS-AGIWE--GGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDEEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDVKKEEEERLRQKNEVTLSIPVDHPVRKLFQKFK-----QQKELRNQGS-AQSDPERSQ---------LQVESRPLQNGASITG-----------TSVVTVSQITPIQTSLAYVKTSETLKQNNRDAMELKP----NGGAEPKCLKVNSPIRMK-NGNGKGWLRLKNNMGAH--------------------------------------------------------EEKKEEWNNVTKAESMGLLSEDPK-------GSDSENSVTKNPLRKTDSCDSGITKSDL------------------------------------------------RLDKAGEARSPLEHSPSQADAKHPFYP----IPEQALQTTLQEVKHELKEDIQLLSCRMTALEKQVAEILKLLSEKSVPQTSSPKPQ-------IPLQVPPQIPCQDIFSVSRPESPESDKDEINF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920E3-1", "uniprot_id": "KCNH5_MOUSE", "id": "Q920E3-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH5", "aln": "--MPGGKRGLVAPQNTFLENIVR---------RSSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKSS--TCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKN-----------------RTPVWFYMQIAPIRNEHEKVVLFLCTFKDITLFKQPIEDDSTK---GWTKFARLTRALTNSRSVLQQLTPMNKTETV-HKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLALSIGTPYRYNTS-AGIWE--GGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDEEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDVKKEEEERLRQKNEVTLSIPVDHPVRKLFQKFK-----QQKELRIQGS-AQSDPERSQ---------LQVESRPLQNGASITG-----------TSVVTVSQITPIQTSLAYVKTSESLKQNNRDAMELKP----NGGAEPKCLKVNSPIRMK-NGNGKGWLRLKNNMGAQ--------------------------------------------------------EEKKEDWNNVTKAESMGLLSEDPK-------GSDSENSVTKNPLRKTDSCDSGITKSDL------------------------------------------------RLDKAGEARSPLEHSPSQADVKHSFYP----IPEQALQTTLQEVKHELKEDIQLLSCRMTALEKQVAEILKLLSEKSVPQTSSPKPQ-------IPLQVPPQIPCQDIFSVSRPESPESDKDEINF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCM2-1", "uniprot_id": "KCNH5_HUMAN", "id": "Q8NCM2-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH5", "aln": "--MPGGKRGLVAPQNTFLENIVR---------RSSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKSS--TCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKN-----------------RTPVWFYMQIAPIRNEHEKVVLFLCTFKDITLFKQPIEDDSTK---GWTKFARLTRALTNSRSVLQQLTPMNKTEVV-HKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLALSIGTPYRYNTS-AGIWE--GGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDDEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDVKKEEEERLRQKNEVTLSIPVDHPVRKLFQKFK-----QQKELRNQGS-TQGDPERNQ---------LQVESRSLQNGASITG-----------TSVVTVSQITPIQTSLAYVKTSESLKQNNRDAMELKP----NGGADQKCLKVNSPIRMK-NGNGKGWLRLKNNMGAH--------------------------------------------------------EEKKEDWNNVTKAESMGLLSEDPK-------SSDSENSVTKNPLRKTDSCDSGITKSDL------------------------------------------------RLDKAGEARSPLEHSPIQADAKHPFYP----IPEQALQTTLQEVKHELKEDIQLLSCRMTALEKQVAEILKILSEKSVPQASSPKSQ-------MPLQVPPQIPCQDIFSVSRPESPESDKDEIHF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRD3-1", "uniprot_id": "A0A8M1RRD3_DANRE", "id": "A0A8M1RRD3-1", "name": "", "aln": "--MPGGKRGLVAPQNTFLENIVR---------RSSETSFLLGNAQIVDWPVVYSNDGFCKLSGYHRAEVMQKSS--TCSFMYGELTDKKTIDKVRQAFDNYESNCFEVLLYRKN-----------------RTPVWFYMQIAPIRNENDKVVLFLCTFKDITVFKQPIEDESTR---GWTKFARLTRALTNSKSTIQQITPVSRTDVTSHKPSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCTFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNVTWLVLDSVVDVIFLVDIVLNFHTTFVGPGGEVISDPNLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEQTNTIKTDSWLFQLATSIGSPYRYNASGTGQWE--GGPGKDSLYITSLYFTMTSLTTIGFGNIAPTTDGEKIFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRSLAVEFQMIHSAPGDLIFHAGESVDLLCFVVSGSLEVIQDDEVIAILGKGDVFGDVFWKETTLAHSCANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLFLTCNLRKRFVFRKIIDVKKEEEERQRSKNEVPLTIPVDHPVRKLFQKFK-----QQKELRNQGASAQLDLEKNQH-------HLQQPARMSKPHTSLMQNSLHAVQNGSTSSVVTISQITPIQNCLAYPKPGDSIKQNNRDFMELKPAVV-TSEQVANRLKVNNTARTKPAGAARGWMRLKNNRAAPGSPPE---------------------------------------------------DERKEGLNNAAKAVSMERIASEVKVQ---IENVEDVGGSRKSSLRKTDSLDSGLTYSDQ------------------------------------------------RLDRVSEPQSPVPGTG-------EVYP----SSESSFQASLQEARLELRMEIQALNGRMATLEERVGQILRLLLDSSKAKSSE------------DLTHRPKLKAQSSIPVSNLSTPDSEKDEGLP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63472-1", "uniprot_id": "KCNH1_RAT", "id": "Q63472-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH1", "aln": "MTMAGGRRGLVAPQNTFLENIVR---------RSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--ACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCK---GWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQ-NNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWE--GGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFR-----QQKEARLAAERGGRDLDDLD-----------VEKGNALTDHTSAN-----------HSLVKASVVTVRESPATPVSFQAASTSTVSDHAKLHAP---------GSECLGPKAGGGDPAKRKGWARFKDACGKGE------------------------------------------------------------DWNKVSKAESMETLPERTK----------ASG---EATLKKTDSCDSGITKSDL------------------------------------------------RLDNVGEARSPQDRSPILAEVKHSFYP----IPEQTLQATVLEVKHELKEDIKALNAKMTSIEKQLSEILRILMSRGSSQSPQD-----------------------TCEVSRPQSPESDRDIFGAS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60603-1", "uniprot_id": "KCNH1_MOUSE", "id": "Q60603-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH1", "aln": "MTMAGGRRGLVAPQNTFLENIVR---------RSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--ACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCK---GWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQ-NNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSGKWE--GGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFR-----QQKEARLAAERGGRDLDDLD-----------VEKGNALTDHTSAN-----------HSLVKASVVTVRESPATPVSFQAATTSTVSDHAKLHAP---------GSECLGPKAVSCDPAKRKGWARFKDACGKGE------------------------------------------------------------DWNKVSKAESMETLPERTK----------APG---EATLKKTDSCDSGITKSDL------------------------------------------------RLDNVGETRSPQDRSPILAEVKHSFYP----IPEQTLQATVLEVKYELKEDIKALNAKMTSIEKQLSEILRILMSRGSAQSPQE-----------------------TGEISRPQSPESDRDIFGAS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95259-1", "uniprot_id": "KCNH1_HUMAN", "id": "O95259-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH1", "aln": "MTMAGGRRGLVAPQNTFLENIVR---------RSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--TCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCK---GWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQ-NNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWE--GGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFR-----QQKEARLAAERGGRDLDDLD-----------VEKGNVLTEHASAN-----------HSLVKASVVTVRESPATPVSFQAASTSGVPDHAKLQAP---------GSECLGPKGGGGDCAKRKSWARFKDACGKSE------------------------------------------------------------DWNKVSKAESMETLPERTK----------ASG---EATLKKTDSCDSGITKSDL------------------------------------------------RLDNVGEARSPQDRSPILAEVKHSFYP----IPEQTLQATVLEVRHELKEDIKALNAKMTNIEKQLSEILRILTSRRSSQSPQE-----------------------LFEISRPQSPESERDIFGAS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HN80-1", "uniprot_id": "A0AC58HN80_DANRE", "id": "A0AC58HN80-1", "name": "", "aln": "MRHHHSERPLAFLPITLCLVPLTCFLPMPSCALSTDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--TCSFMYGELTDKDTSEKVRLTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQEKVVLFLCTFSDITAFKQPIEDDSSK---GWGKFARLTRALTSSRGVLQQLQPTVHKGENVHKHSRLAEVLQLGSDILPQYKQETPKTPPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNVTWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDENWNHRA------------------VTQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWLACIWYSIGDYEVIDEDRNTVRTDSWLYMLAESIGTPYRFNASGTGRWE--GGPTKDTVYITSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIASTWSMSHGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTIHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEVTLAQACANVRALTYCDLHVIKRDALQKVLEFYTAFSNHFSRNLLLTYNLRKRLVFRKISDVKREEEERLRRKNEAPLNLPPDHPVRRLFQRFR-----QQKEARLAAVRP--NSEDSD-----------LEKG-QIHNEVISQ-----------DVIATTSIVTVTESPATP--IPSHLIKNR-TLGPFDQA---------KLSAPAPNASRMSEPRARGWARFRESVAKPE------------------------------------------------------------SWGNVPKAESMETLPERSS----------SAKTSEPSGLKKTDSCDSGITKSDL------------------------------------------------RLD-EGGIRTPVDRSPVQPDGKSPPIPPIPTIPEHTLQASLLELRTELKEELSALGNRMVALEAQVAEVLRLLRNRKSPTSPMS-----------------------LFQISRPTSPDTDKEDMFP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AXZ2-1", "uniprot_id": "A0A8M3AXZ2_DANRE", "id": "A0A8M3AXZ2-1", "name": "", "aln": "--MAGGRRGLVAPQNTFLENIVRRSNVWTFSHRQTDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--TCSFMYGELSDKETSEKLRQTFENYEMNSFELLMYKKN-----------------RMPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSSK---GWGKFARLTRALTSSRGVLQQLAPTVQRGENVLKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCTFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNVTWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYVKTWFVIDLLSCLPYDVINAFENVDE---------------------------GISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWLACIWYSIGDYEVIDQDANMVRTDSWLYLLGEAVGQPYHFNASGSGKWE--GGPSKDSVYITSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTNIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTDKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTIHSAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEVNLAQSCANVRALTYCDLHIIKRDALQKVLEFYTAFAGHFSRNLVLTYNLRKRIVFRKISDVKREEEEMLRRKNEAPLNLPPDHPVRRLFQRFR-----QQREARLAAERA--NQVEQD-----------VEKG-KSE-QTVVK-----------EITSPTSIITVTESPATLNTLSPTTPSTK-TLCRAKLN---------TPLAPNTAQKSAEAPKSKGWSRFKEATAKSDL-----------------------------------------------------------SLSSVSKAESMEMLPDRTK----------SQD--ELLSLKKTDSCDSGITKSDP------------------------------------------------RLDNMGSAETPQDRSPVQPEEKRLFYP----IPEHSLQACFSELRQDLQGDIHSLGCRMSALEGQLAEMLRLLAERNS-SGPAE-----------------------LHHISRPNSPDSEKDDNISS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02280-1", "uniprot_id": "KCNAE_DROME", "id": "Q02280-1", "name": "Potassium voltage-gated channel protein eag", "aln": "--MPGGRRGLVAPQNTFLENIIRR------SNSQPDSSFLLANAQIVDFPIVYCNESFCKISGYNRAEVMQKSCRYVCGFMYGELTDKETVGRLEYTLENQQQDQFEILLYKKNNLQCGCALSQFGKAQTQETPLWLLLQVAPIRNERDLVVLFLLTFRDITALKQPIDSEDTKGVLGLSKFAKLARSVTRSR----QFSAHLPTLKDPTKQSNLAHMMSLSADIMPQYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFKNKTSEDVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYLKSWFIIDLLSCLPYDVFNAFDRDEDG---------------------------IGSLFSALKVVRLLRLGRVVRKLDRYLEYGAAMLILLLCFYMLVAHWLACIWYSIG-----RSDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNGPSRKSMYVTALYFTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDDEVVAILGKGDVFGDQFWKDSAVGQSAANVRALTYCDLHAIKRDKLLEVLDFYSAFANSFARNLVLTYNLRHRLIFRKVADVKREKELAERRKNEPQLPQNQDHLVRKIFSKFRRTPQVQAGSKELVGGSGQSDVEKGDGEVERTKVFPKAPKLQASQATLARQDTIDEGGEVDSSPPSRDSRVVIEGAAVSSATVGPSPPVATTSSAAAGAGVSGGPGSGGTVVAIVTKADRNLALERERQIEMASSRATTSDTYDTGLRETPPTLAQRDLIATVLDMKVDVRLELQRMQQRIGRIEDLLGELVKRLAPGAGSGGNAPDNSSGQTTPGDEICAGCGAGGGGTPTTQAPPTSAVTSPVDTVITISSPGASGSGSGTGAGAGSAVAGAGGAGLLNPGATVVSSAGGNGLGPLMLKKRRSKSRKAPAPPKQTLASTAGTATAAPAG--VAGSGMTSSAPASADQQQQHQSTADQSPTTPGAELLHLRLLEEDFTAAQLPSTSSGGAGGGGGSGSGATPTTPPPTTAGGSGSGTPTSTTATTTPTGSGTATRGKLDFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* *. *: : . ::.*:*.******:*:**.*:.***:***:**:*****. .*.******:**.* ::. :::* : : **:*:*:** . *:*: :::******.: ***** ** *** :****:.:. : * ***:*:*::* *: *: . * *.**.::.*.:**:***:**:*******:****.**: ***:** *******:*****:**.: :::: **:**:*****::*************.***:***::*****:*:**:**********::***:. :: *.****:************.****:*:*****:*:**:*.: *.***:******** . . ***: *. ** : * * .** :.::*:::******.:*::****:*. ** **:*::.:*::.:********:**.*:*** : * :**:***.**:*:**::***.********:.***:*::*:**:***. *****:************:**************:**:.* *.*****::*:***:* ***:*:********:**:*********** ***: :.::.************ ***: * :**:**:**: *:*** ** ***:*::***: ***:*:* : *** * ** **::*.:*: * . . . : : * :. : . .: . . ..... * . *.. *: :* *. * . :* : * . : : : : . . .: .: : . . * :* : ", "identical_positions": 422, "similar_positions": 236, "identity": "34.59%" }, { "cls_id": "homologset.agr.FB:FBgn0000536", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRW8-1", "uniprot_id": "EKI2_RAT", "id": "D3ZRW8-1", "name": "Ethanolamine kinase 2", "aln": "-----------------------------------------MAVPPSAPVPCSPFYLRRQEACPQCSWSMEEKA------------------VASASCWEPPG--PPR-AAVPCFAIAVDQDD---ILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEED----------------------------------------------------MRDCVLVRVYGEWTELLVDRENEIRNFQLLRAHGCAPKLYCTFQNGLCYEYMQGVALGPEHIREPQLFRLIALEMAKIH-TIHAN----GSLPKPTLWHKMHRYFTLVKD-----EISPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGHVRFIDYEYAGYNYQAFDIGNHFNEFAGVNEVDYCRYPAREIQLQWLRYYLEAQK-----GTAASPREVERLYAQVNKFALASHFFWALWALIQNQYSTINFDFLRYAVIRFNQYFKVKPQVSALEMPK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7MCT6-1", "uniprot_id": "EKI2_MOUSE", "id": "A7MCT6-1", "name": "Ethanolamine kinase 2", "aln": "-----------------------------------------MAVPPSAPVPCSPFYLRRQEPCPQCSWSMEEKA------------------VASAGCWEPPG--PPR-AAVPCFSVTVEQDD---ILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEED----------------------------------------------------MRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQGVALGPEHIREPQLFRLIALEMAKIH-TIHAN----GSLPKPTLWHKMHRYFTLVKD-----EISPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGRVCFIDYEYAGYNYQAFDIGNHFNEFAGVNVVDYSRYPARETQVQWLRYYLEAQK-----GTAASPREVERLYAQVNKFALASHFFWALWALIQNQYSTISFDFLRYAVIRFNQYFKVKPQVSALEMPK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVF9-1", "uniprot_id": "EKI2_HUMAN", "id": "Q9NVF9-1", "name": "Ethanolamine kinase 2", "aln": "-----------------------------------------MAVPPSAPQPRASFHLRRHTPCPQCSWGMEEKA------------------AASASCREPPG--PPRAAAVAYFGISVDPDD---ILPGALRLIQELRPHWKPEQVRTKRFTDGITNKLVACYVEED----------------------------------------------------MQDCVLVRVYGERTELLVDRENEVRNFQLLRAHSCAPKLYCTFQNGLCYEYMQGVALEPEHIREPRLFRLIALEMAKIH-TIHAN----GSLPKPILWHKMHNYFTLVKN-----EINPSLSADVPKVEVLERELAWLKEHLSQLESPVVFCHNDLLCKNIIYDSIKGHVRFIDYEYAGYNYQAFDIGNHFNEFAGVNEVDYCLYPARETQLQWLHYYLQAQK-----GMAVTPREVQRLYVQVNKFALASHFFWALWALIQNQYSTIDFDFLRYAVIRFNQYFKVKPQASALEMPK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HBU6-1", "uniprot_id": "EKI1_HUMAN", "id": "Q9HBU6-1", "name": "Ethanolamine kinase 1", "aln": "----MLCGRPRSSSDNRNFLRERAGLSSAAVQTRIGNSAASRRSPAARPPVPAPPALPRGRPGTEGSTSLSAPAVLVVAVAVVVVVVSAVAWAMANYIHVPPG--SPE---VPKLNVTVQDQEEHRCREGALSLLQHLRPHWDPQEVTLQLFTDGITNKLIGCYVGNT----------------------------------------------------MEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPKHVCNPAIFRLIARQLAKIH-AIHAHN---GWIPKSNLWLKMGKYFSLIPTGFADEDINKRFLSDIPSSQILQEEMTWMKEILSNLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPDRELQSQWLRAYLEAYKEFKGFGTEVTEKEVEILFIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKVPE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LLY9-1", "uniprot_id": "A0ABK0LLY9_RAT", "id": "A0ABK0LLY9-1", "name": "ethanolamine kinase", "aln": "---------------------------------------------------------------------------------------------MANYIHVPPG--SPE---VPKLDVTVQDQEEQRCRDGALSLLQHLRPHWDPREVTLQLFTDGITNKLIACYVGDT----------------------------------------------------MDDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPQHVCNPAIFRLIARQLAKIH-AIHAHN---GWIPKSNLWLKMGKYFSLIPTGFADEDINKRFLSEIPSPQLLQEEMTWMKEILSSLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPDRELQGQWLRSYLEAYKEYKGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKMPE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4V0-1", "uniprot_id": "EKI1_MOUSE", "id": "Q9D4V0-1", "name": "Ethanolamine kinase 1", "aln": "---------------------------------------------------------------------------------------------MANYIHVPPG--SPE---VPKLDVTVQDQEEQRCRDGALSLLRHLRPHWDPREVTLQLFTDGITNKLIACYVGDT----------------------------------------------------MEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPQHVCNPAIFRLIARQLAKIH-AIHAHN---GWIPKSNLWLKMGKYFSLIPTGFADENINKRFLSEIPSPQLLQEEMTWMKELLSSLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPDRELQGQWLRSYLEAYKEYKGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAVVRFNQYFKMKPEVTALKMPE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54352-2", "uniprot_id": "EAS_DROME", "id": "P54352-2", "name": "Ethanolamine kinase", "aln": "MGTETKSNSYTGQISTSGGNPKVMKDSLSLVRQTVNQQTLSLSQSNQVQNQLNSHSNSNSYPNPSGSENKNENE------------------QNSRDIRAKPEDKSRKEAIVPFVPIFVEEAD---VIQGAKELLKVIRPTWDLSHVEFKSFTDGITNKLVGCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDDRAADDGSPVQYSDNVVLVRIYGNKTDLLIDRKAETQNFLLLHTYGLAPSLYATFKNGLVYEYVPGTTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPERFSDAEKHKRVKETFLPIGRLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIYTQSLNTVNFIDYEYADYNFQAFDIGNHFAEMCGVDEVDYSRYPKREFQLQWLRVYLEEYLQ----RSNIQNDEVELLYVQVNQFALASHIFWTVWSLLQAEHSTIDFDYVGYAFLRYNEYLARKVEFLSLTAAKNNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . . *. . : *: : ** *:: :** *. .* : *.*******:.*: : : ****:**: *:**:**. * :.* :*:::. **.**.**:*** **:: * :* .. : * :: *:* .:*::* :: : . * . :* * :: *: : . . *..*: : * *. * **:*:.***** *:** . . * ******:.**: *:****** *:.**. ***. ** ** * ***: **: **: *: ***:******:** :*:*:* ::***.**:: **.:*:*:*: * : :* .: ", "identical_positions": 132, "similar_positions": 102, "identity": "25.38%" }, { "cls_id": "homologset.agr.FB:FBgn0000541", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVH2-1", "uniprot_id": "A0A8I5ZVH2_RAT", "id": "A0A8I5ZVH2-1", "name": "", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPP-ASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPP-ASASSASGPGRGGRGGGGGRTGGGGG--HLARTTSARRAVNKVVYDDHESEDDDEEEDMVSEEDEEEEEDGDAEETQDSEDDEEDDMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVESKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKVWYYSTKVQLAELIDCLDKDYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQ--NPEDTEKDKNEGENDSSKGAEKSREESEDQSPDKDADGKVLEEEPGQGKPEEPTEVGDKGNSVPANLGDNTRNASSEET-PCEGRSPEGWLSETHDSS-TAEKKVASELPPDVPEDSHK-TCDSSNTSATTASSQPNLENCSSSSSSSELTSSQSDSAKAADDPDIGERDSHTPVSVQEEIG-DFRLDKSNGEVSESPGTGKGTSGSTRIITRLRNPESKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVRHQVWKQKGEEYRVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLEGVKNNMDENKDESDKRKSPRSPKKMKTECDSEKGEARDADSTAGATAGTMELSKLPEKEEHDVKELLDPDNDKPFKEEPMEIDDSVKTESHMNSEESAQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPTGAVKSSSEPPVSTKADEGHQGDLLRQEQRSTPSQAGTADLGLGASQSDPLVLGISPPSLSTGKPDPKGQVLDDVSIQSPGPACQGQNSVESDLDARISEATSKGLELSQTKTKVTDSLTDDSKPTSADEGSTLICKSKKPLPQDDCSTAVSSSSKSTLPAPVPKSPRDRDARAFPKAMDLDGRLGGDSEYNSTLENNSGTMYMRDSSEEDMVVQNSNDTTSKRFITPDQGMESTEPTKCQLVS-KSTENCDNRLQGKVTEANGKKLGQHQ-KPEERAVNRCADQVSLRHSADRKNSEARESEKRGQKANKFQINGKDSKAKGYLKGPGMKDVSDGKVMSGAVEPKVNNINKVIPGN-IKSLAGKESAVKPFVNGDIIMEEFSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKDSASTQVIIPPAPCPDRNSLNQVEDMETE---GPEVKKVTPSPITTGEDSNLGKDVMDENGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIK-----VAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDSDVDTVSVKEQSKTVVTTTVTDSLSTAGSTLVTSMTVSREYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPCFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVVIESWVAEEELELWEIRAFAERVEKEKAQAVEQ--------------------------QTKKRLEQQKPAVIAASTTSPTNSTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGVVQVQQKVLGIIPSTAGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRAPLQQP-ALGKAVIRTPVTMQPGAPQQVVTQIIRGQPVSTAISASSTASSAPVQKGLTPGAAAGTLQPSAPHSPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTPVTAVSSSS--SSSSTNATATGSGEQKQSKLSPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPP--------AQPEVQTQPAASSHVPSETQPSQAQSSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVPSPSRPQPQTQQPQPQVIAVPQLQQ-VQVLSQIQSQVVAQIQAQQ---GGAPQQIKLQLPVHVQQNS--AAQAQHAQSVLTVQAASVREQLQRVQQLRDQQQKKKQQ-IEMEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKELQMQVQEELKRD-LKMKREREMAQVVQANAAAGPTPSVPAPVPAPAPAPAAPPAPP-SPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDS--KSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDLCTNWYHGDCVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWFHGRCVGILQSEAELIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A654-1", "uniprot_id": "A2A654_MOUSE", "id": "A2A654-1", "name": "", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGG--HLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQ--SPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEEPTEVGDKGNSVPANLGDNTTNASPEETSPCDGRSPEGCLSETHDSSSMAEKKVASELPPDVPEDSNR-TCDSSNTSATTASSQPNLETCSSS----ELTSSQSDSAKAADDPEIGERDSHTPVSVHEEIG-DFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVKHQ----------VTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSS-KSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVS-KSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGN-TKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETE---SPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIK-----VAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQ--------------------------QTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQP-ALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPP--------AQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCP-----QPQPQVIAVPQLQQ-VQVLSQIQSQVVAQIQAQQ---SGVPQQIKLQLPIQVQQNS--AAQT---QSVVTVQAASVQEQLQRVQQLRDQQQKKKQQ-IETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRD-LKMKREREMAQAVQANAASVPTPSVPAPVPAPAPA--APPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDS--KSKKKKMISTTSKEAKKDTRLYCICKTPYDES----------------------------------------------------------KFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12830-1", "uniprot_id": "BPTF_HUMAN", "id": "Q12830-1", "name": "Nucleosome-remodeling factor subunit BPTF", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPP------------TSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEE--EEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKG-DIDNVK--SPEETEKDKNETENDS-KDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNK-TCESSNTSATTTSIQPNLENSNSS---SELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSS-KSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQK-KLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIE---TSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIK-----VEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQ--------------------------QAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS-TLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT----TTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ---SGVPQQIKLQLPIQIQQSS--AVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRD-LKIKKEKDLMQLAQATAVAAPCPPV-----TPAPP--APPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDES----------------------------------------------------------KFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQI5-1", "uniprot_id": "A0A8M3AQI5_DANRE", "id": "A0A8M3AQI5-1", "name": "", "aln": "MRGRRGRPPKAQLVQEPS--------------------------TGPVRGLRPRRSLKPKVKGGSDEDYVTPKRGTHHHSTRGRRK--------ARSTASR----GRGRGRGTARGRGR----------RSTASGVVYDDHESDEDDE--DAVSLR---SEEDEYIEEPLTDEEEEEEEEEAINDESDYLEELDELDEDDASYCTESSHG-----SNTVGRKRPRPRRPPSPILEQKEIPLLELPNSSEDLLLPNEQLLNALAIYEVLRSFCTVLRLSPFRFEDFCAALVGQEQCTLMAETHICLLKAILREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVVRSYCESDPEYHH-VLPDLEGEDYPFSPLESKIKVLQFLVDQFLTTNLAREELMSEGVIQYDDHCRVCHRLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEICVAHKVPGVTDCLTEFQKSRPYIRQEPIGFDRHQRKYWFLNRRVVVEEDGEDDS-KQIWYYSTKVQLGELLELLDKGFWENDLCSVLEEMREEIHAHMDITEELTNKARGNNKAYLTVANDVILDRLKTKQEAELEEVKRRAAEEAERAKLEPKTLSDEPASGDQMSSNDSCPQQDSSNGNARNE--QTSSDASVSAVPVGEVLSSSVPEIAASSSSTVQTKPDSQSPIG--NAVTSSSSGEEKGEGTDGVEELTGKSSEGACHGEGDSVLEAELAQTADENSCS-----SHFSISECLRGPDEPDLVDRSSQSSLNSQDDTG----DGKANGDSTKT--------ASSRMITRLRNPDSKLSQRKVMQDKDGSSQDGSRALKETP---PLSSFGTFKRDSSK--------SSGFFKLGQEGKFRVYHNQYSTNTLALNKHQHREDHDKRRHLSHKLCMTPAGEFKWNGSLYGSKALTVSTLRLTIIQLENNIPAPFLHPNWASHRSNWIKAVQMCSKAREFALALAILECAIKPVVMLPVWKDSLGHTRLHRMTSVEREEKEKVKKREKKL---EDEETMQQATWVKYTFPIKHQVWKQKGEEYRVTGYGGWSWVSKTHVHRFFTKLPGNTNVNYRKALEAAKTGMDNQAALPGAPKTVVKKDEMSSQNVPDKDNAQVLSLDSSEEKLSVEKDHVLKVEEQDEEKMNETTEEKCNEKN--ESVEEMDTSSPNSANEG-KVEITNAST----------DDSTMKEEPLDSEVVKDNTLNQPQ-----------QCFWHDVVNVSEGFLQRTAYKKLKPSKLDGLLERRVKQFTIEEKQ--------------------RIDKLKQAPTSKPLTETAVENKETTLAAQD----------------------HKVKIEGTISETPKARQTEGVACLAIQEKD---------------------------------------NVVKRLVFNQEDEQAKTNTSGQKNTLDVRLNDSVELAPKENQQKLAETDPKTAS--------------------RVAMSELNGNSQSLDQSLSLNAKPDKNITEATCPPEDSAGKDNIENSENDLDVKKTVPVQVNGKDVTVDPECKN--LTDNGDTKELTNTIVEDIKAISPKEPVKSLMNGDATQECLKEWTNSTIPQVNLDEEKAVTKLDPDYPPPQKVAKLENNIEKPIDSSVSLSVPEPSPVASEPNERSEVPSHSSKVEPMQVVEAKPSVPSPVPSAEESSLSSDLTE--------NSSSIGET---TVVTQVTTTTTTVSTESRMVLTSRDSLASKNGLNTAVLTDSKVESSSSVSTLSSTTTTTVTKVLSSSQEATLTTECKTMVMKTLTDTTSSPSGSTVKSMTVSHEYSTRDRVRLLKFSRTKKTRSGTALPSYRKFVTKSSKKSIFVLPNDELKKLARRGGIREVPIFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVRSLAGVSLMLRLLWACLRWDDMSVKPSPTGGTTRTETSDTDITTTEIIKRRDVGPYGIRSEYCIRKIICPLGVPETPKETPTPQRKGLRSSALRPKKPEPAKQTGPVVIETWVAEEDLELWEIRAFTERVEREKAQAADPTKVSVQKKAEEVKAQLEAQLKQQRLAAQQKRLEQQKPSTTSN-TTTLTSTPTTPGTTTQKVVVGSISGQVTSTPKVVMTTKLGSP--VTFQQNKNFQQSFASWVKQGQQGNSVSTSSVVTVAASSATTSGQTFHIAAAPGSMAGSVIAAKLPVPANSKIVTVNVPTTQGGLVQVQQKVVGIIPSSTAGNAQSFPPFQPRTATINIRPNTT----TSTQQVLTTGTTLRPGMTVIRSPLQQATTLGKTIIRTPLMVQQGQTQQQVQTSSGTQVVGTPPRLP-----TPNQ----------PQTPQTPASPRPQQGQVKLTLAQLTQLTQGAQGGNQGLTVVIQGQGQTTGQLQVIPQGVTVIPGPGQQLMQAAMPNGQVQRFLFTPMAPAPTPAPAPVS---------------------APAAPSNTTPSSVPPAAAPTAVTSTTPAPIQTAARLAPQPQPP-----------------------PSLPPPPSVPPSQPVQHTPAPIQTAVIPQP-----TPP---IQPHPPVQLRPQPQLPPQNPVVPPTPVSTPQIAQVTATAPPQQITTLPVTQTTVTKVQPQIQLP---------------PQLLSVPGLQQ--QVLSHIQSQVAAQIQAQVGTTAGMPQQIKLQLPIQIQQQGGGQVQAHQIQNLVTIQTASVQEQLQRIQQLCEQQQQKKKQ-QEAKREQAQQHVSQSDLIQKQVAQKQNVAIEQLKQKKTMTPAEREENQRMIVCNQVMKFILDKIDKDERQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKADILKKRALLDKELQLQVQEELKRDLIKLRREKEKAQAAAAQAAAA-------------------AAAAAAASTHVHSGLSSYTGTVTSPTSTHKRKREEERDAA-KPKRKKMISTTSKDSKRDIKLYCICKTPYDESKFYIGCDLCSNWYHGECVGITEKEAKKMDDYICSECKRAQEGNTEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEATHIDEYVCPQCQSTEDA-MTVLTPLTDKDYEGLKRILRSLQSHKMAWPFLEPVDPNDAPDYYGIIKEPMDLSTMEERIQKRFYSKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEFLESFFVQKLKAFKASRSHNNKLQSSAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0T1-1", "uniprot_id": "NU301_DROME", "id": "Q9W0T1-1", "name": "Nucleosome-remodeling factor subunit NURF301", "aln": "MSGRGSRKRGRPPKTPNER-------------------------ASGRFNYQLLKKPKYLSEGKSQPSTPSASRGISPQSD-------------EGSRSSHNNHTNRSRGSAAKRGRGR--------------KSAVQPNTSS---------------YSGRKGYESEYHYGSDFGDSEEDKSDNEDDMLLTPSDDESLEVANESESEFSVCSFNQNGVGRPPRPPSPEPVWLQEGRQYAALDLPDSSEDLFIANTHVLRALSIYEVLRRFRHMVRLSPFRFEDLCAALACEEQSALLTEVHIMLLKAILREEDAQGTHFGPLDQKDTVNISLYLIDSITWPEVLRSYVESDKTFDRNVFHILSHTEYPYTGIDNRLEVLQFLSDQFLTSNSIRDVMLQEGPIHYDDHCRVCHRLGDLLCCETCPAVYHLECVDPPMNDVPTEDWQCGLCRSHKVSGVVDCVLPQEKQGVLIRHDSLGVDRHGRKYWFIARRIFIE----DQENFTCWYYSTTSKLKLLLSRLDAEELETRLHSQITERRDEIERQMKLTETLTNEHKHTKRSVIEIEQEAKNELLEKEVLDEDEKDG--------------------DAKSESQSIEGTKKQEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------CKMVTRQKSNQLTNG-------------------------------------------------TLHFKLGMEQGFKNYVNQYSTNPIALNKPQRNEERDKRRHLSHKFSLTTASDFKWIGITMGTTDNMITTLRQTLINFESNIAASFLNINWVVNKKIWNAAVMNARRPSEFAVVLLLFQASLKSVVFANVWHEQLGHTTLQRITSAEREERKKLEKREKRERDDEEERNRLAFNYIKYTLGLKHQVWKQKGEEYRVHGQWGWLWLSSSRRCGVRARRAQPLTHNRVYVHYTMGEENDVNEIILVDPRTQRFMQQCESSN-VDGQVCHYLPDQYKNVKVIEDVTEKIKGHIDVSKALNAPGRTYYSKVARKSRLDDLLDRRLKLAEVEEQMASKIPSDMKPLLVSSQNNTANSKQTFLEKRLLRLTEVQAKG---------GPANVNLELVNSLAKQIQTVRLQFSQLNRFAKVFRCYTKECNTNSNAVSQITQNTCYSPLCLQKARAKKELLLLLRKAHTAGNGSKETVAAILGAVK--------KPSILEQKLTEGKRESTQVAVDDSEEGKPAESEAPLDLLQDWEHARAHAVPFSDS----------------------LLTECILVDQECVTNTKIKQEVNASSGCNTTPDSNTQDSDKIDYIESMDVCSNVEIESTEDS-------------------IVTGLNSGNAEDVDMTPGWRRKRNQKSKKSYIGTKDVLDQTLDKDIPLNKQ-NRRFPITARPVKRECVKKYERETFENGNERVYSTSSPRGRVYLLN---------------DAAKLYEQAVKTEDKSTITKKPSYSRYPLISNFLTHKKKRSLLVLPRFELLKLARLGGKSSTNGFHHAAKNNTIWQYQ--CSRPLFRTCWSYRTSNATSLSSLALQLRILWSCLRWDDMIAKPPSTDGKHQVTTDTEIVTLELLKLRHS-----GRYGEKTSYLRRKVVIPLEMPKTVREVTSIRSGLRKRKRAESPQPTEPQITEEWVDEDKLELWEIKFMGEKQEKARLSAVTRSVASRQLEASGS-NGSNTSTNGALGVAGRVQLAPKLSEDVKEKMEQQLKLQRAVHQQRKLVATGEITRSVTPVKGQVIGSRRVIVKNPDGTTRIIQQAVTQVSRTGGANTAAAAASPTVGGSTSTQSNPSTSTPHKVQIIRGPDGKVSVRGLNPGQQLVQMPDGKLHVLTTTTSSNSAGQGNKMKVPIKPASTSSSPAISSAQTTTNPVTPVIKQIAVKHVTKNSATQSIASS------------------------SRVALPLAQIKNKLLLAQQQQQSTSSSPATSSSPVQKIVSKVVNTSTSGQTLQQVFVQSGSKLVVGQNAQGQKVIISTSAAQQ-----------------------------------------------------------QGTSPVQQQQLVQSQPIQQSPQQISMTQVGNQPTQKVIQQIVNTSNVQQQIVVGGQRIILSPGQTIVTQRNVPQ-SQALQMVQQQIQTQQQQQQHHVVQPQQQFVVQSNQIVQSS-----------------PSAQTKLVKQLVVQQQSQQTIEEKTQITTTDSNETGTQQVLVPN---STLAQQLAQGKLQVATVNGQQVIVKPLGNNQAQIVAHIKHQGDGNAHIVTSN--------------------------SATAVPQANPQTSPVKQQALPPQSPQQVVVQQQQIHQQ------------------SPTNFESGVTPITQQPVLTQAVQAPAQQQALSVEESLLQNQPPGTVIKCVTAQVLQTEHGPRIVLQGLVGNDFTAQQLQLVQTQVKQQLMKAQESNGKLGVLGPTKIYLAVQ-------------PENAVQSQPPPLTPVHQSAAHQQTNNIEIDADTLATTYEANSTIKDIAINNGDDQENSKCAETENSNITTNESFAGTSSLLEGSEHDEPTNLAGLDISETDLENKQNESFVVTRGYIQKS---ISNALKQGNLSPELEEK----LVCMQKQQENANSTNEWETCSRGSVNEEALTPSRQTDDTEWKIRTSLRRPNAMTTSSQFNRILKKNRSKNDEVAELGEQKQSQLERHKELLKKNILRKRSLLERNLQS-----------EIHEDVKTKVQRHVRPLSNASPDEQSENERSGEPNLDFKRTEVQNPRHGAGRPKKLTRKKEKLYCICRTPYDDTKFYVGCDLCSNWFHGDCVSITEEASKKLSEFICIDCKRAR--ETQQLYCSCRQPYDESQFYICCDKCQDWFHGRCVGILQSEAEFIDEYVCPECQRKNDANAANMKKLTSNDVEELKNLIKQMQLHKSAWPFMEPVDPKEAPDYYKVIKEPMDLKRMEIKLESNTYTKLSEFIGDMTKIFDNCRYYNPKESSFYKCAEALESYFVQKIKNFRENVFDQRT------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** .* . :. . : : . . : :.. . :* .*. * . * * . .* : .* . .. .* ..: :.: : :::.* .: :. :.: :**.. .. ** : * :: . *::*.*****::.* :::..::****:* * ::***** ***:****. :**.:*::* *: ****:*****:..* *** * **:** :**:**.:*****:* * *** :.: *: . :**: ::.:::***** *****:* *: ::.** *:*********:**********.********.**:::** ::*** :* :***.**.**: :*. :*::.:* ** *****: **:.:* ::. *****. :* *:. ** * * : : *:*:. :*.:** ***: : .::: : :: : :. : : : *. . . :. ::: :::** :. : . . . .**** * :: * ******.:**** *:.*::******:**:.:*.*.:*** * *:. ::*** *: ::*.**.:.**: **. :: * ** . :. ***:.* :::.::*.**: :*::.**** *:*:** ****::*::*:**: *:*.. .::***: ::** * * ** *:*.:: . .: . . * * : : .: . . : : : . : . . : : . : . : : . :: * . . * * .. :: :: . : . . :. : . : : : .. . . ..: : * .:: * . .. . . : : .. .*. * :* : . . : . : ..*.:. . : : .. .: : : :: . . . : : .: :. : :. .. : : :. . : . : . .: . . :. .: : : * : * . . .. .:. :*** * *: * : : . :* . .* .*. . : : . *. . : . . . *: : : ... : .*: .: : . . : *.:* :*: :: ::.. : : .: :* :* : : : *.: : . : .. : . . :*:::.* : ..:**: * : : : * * .. . *.:.: * .. * :* ....: .: .:: : : *. . .:.. :*: * * * :...:.. :.: : . ..:. : : . : * :.. ** : :: : : * :. **::: * . . ::. . :.: *: .. : ** *:: : . ::: : * *: : * : * * : *: : **:* . . *:: . :* *: : * . ***:: .: *. .* . . .. . . . ::.. * . * . * : * * . . * : : *. *: .. : . . . : * . . :. *: . * . * . :*: : . : . : ::: . . . .: : . . : : :::: .: : .. . : .:* :: : * *.: :: .::* .*: :** * : :. :: * : . :.* . .:::.:. *: : * : : :. :.: ::. : :* * ::. ::.:.:: : : . . . . :. : : : . : :: . ..* :::. :*****:****:: :*** **:**:*:************ *******:** .:** : :. **.:* * **.:::.:* ** ****:*****::***** :******* ** ::: . * **:**:.************** ::.**:*** ***:****:* *: . .:.. ", "identical_positions": 469, "similar_positions": 751, "identity": "14.43%" }, { "cls_id": "homologset.agr.FB:FBgn0000543", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA55-1", "uniprot_id": "D3ZA55_RAT", "id": "D3ZA55-1", "name": "", "aln": "----MEGKGRLAMVEDAVEYHLFLIPDEARDTDGHRESLQKYIEQIMTQFAP---ILVPYIWQNQPFNLKYKP------------------AKGGVPAHMYGMTKFGDNIEDEWFIVYIIKQITKTFPELVARIEDNDGEFLLIEAADFLPKWLDPDNSANRVFFHRGELCIIPVPRKSERIPWLPTTPPTIQQALSIISAHPEAILASESVQAAVDRRISGYP-EKIGASLHRAHCFLPAGIVAVLKQRPRLVSAAVQAFYLRDPIDLRACRVFKTFLPET-RIMASVTFTKCLYAQLVQQKFVPDRRSGYGLPPPSHP--RYRAHELGMKLAHGFEILCSKCSPHFSDSRKSLVTASPLWASFLESLRRNDYFKGLMEGSAQYQERLEMAKNYFQLSIHRPESSLAMSPGEEILTLLETLPFDIAELKTEEADLPPEDDDQWLDLSPDQLDQLLQDAAGRKVSQPGPQKEEQQNCDVGQVSDSMKAFISKVSTHKGAELP---RDPSEAPITFD-----------ADSFLNYFDKILGTKPQESDS-DDQDEDDLECLDSDDDLGLEAQES---ESLKGALGSLK-------------SYMAQMDQELAHTCMGKSFSTRKQLD--PPSQTANDNSDEEDSGAGDCTVEAVDVDLNLVSNILESYSSQAGLAGPASNLLHSMGVRLPDNADHHSSQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CS74-1", "uniprot_id": "ECD_MOUSE", "id": "Q9CS74-1", "name": "Protein ecdysoneless homolog", "aln": "----MEGSGKLAMVEDAVEYHLFLIPDKARGTEEHREILQKYIERIMTQFAP---ILVPYIWQNQPFNLKYKP------------------AKGGVPAHMYGMTKFGDNIEDEWFIVYVIKQITKEFPELVARVEDNDGEFLLIEAADFLPKWLDPDNSANRVFFHHGELCIIPVPRKSERIPWLPMTPPTIQQALSIISAHPEAVLASESIQAAVDRRVSGYP-ERVEASLHRAHCFLPAGIVAVLKQQPRLLSAAVQAFYLRDPIDLRACRVFKTFLPET-RIMASVTFTKCLYAQLVQQKFVPDRRSGYGLPPPSHP--QYRAYELGMKLAHGFEILCSKCSPHFSDSRKSLVTASPLWASFLESLKRNDYFKGLMDGSAQYQERLEMAKNYFQLSIHRPESSLAMSPGEEILTVLQTQPFDVAELKTEEADLPPEDDDQWLDLSPDQLDQLLQDAAGRKESQPGPQKEELQNYDVAQVSDSMKAFISKVSSHKGAELP---RDPSEAPITFD-----------ADSFLNYFDKILGAKPQESDSEDDPGEEDVEGVDSDDDVGFEAQES---ESLKGALGSLK-------------SYMARMDQELAHTSMGRSFTTRERLNKDPPSHTANDNSDEEDSGAGDCAVEAVDVDLNLISNILESYSSQAGLAGPASNLLHSMGVRLPDNADHNPQVSQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95905-1", "uniprot_id": "ECD_HUMAN", "id": "O95905-1", "name": "Protein ecdysoneless homolog", "aln": "----MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAP---MLVPYIWQNQPFNLKYKP------------------GKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITKEFPELVARIEDNDGEFLLIEAADFLPKWLDPENSTNRVFFCHGELCIIPAPRKSGAESWLPTTPPTIPQALNIITAHSEKILASESIRAAVNRRIRGYP-EKIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDPIDLRACRVFKTFLPET-RIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDP--QYRAHELGMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLIEGSAQYRERLEMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDLKKEAANLPPEDDDQWLDLSPDQLDQLLQEAVGKKESESVSKEEKEQNYDLTEVSESMKAFISKVSTHKGAELP---REPSEAPITFD-----------ADSFLNYFDKILGPRPNESDS-DDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLDNLK-------------SYMAQMDQELAHTCISKSFTTRNQVE--PVSQTTDNNSDEEDSGTGESVMAPVDVDLNLVSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PDM7-1", "uniprot_id": "A0A8M1PDM7_DANRE", "id": "A0A8M1PDM7-1", "name": "", "aln": "----MDILKRPGIPEDAVQYKLFVVAADPSAPE---KSLQQILQDILAEITP---LLVPYIWQNQPFNLTQHP------------------EKGDVPAHLGGVTEFGDNVEDEWFIVYLLKHITHTFTDIAAVVYDNDGQFLLIEAAEHLPKWLDPDSSENRVFLYHGELHIIPMSSSSGEVGFSRDCVPTVRQALEVLHSHTDRCLAKQTIRSALNQRIHGYP-DKIQQNVHRAHCYVPAGIAVVLSRRPDLIAPAVSAFYLRDPVDLQACRTFHTFPPDT-RVMTSVKFTRCLYAQLQQQSFVPDRRSGFSLPARSHP--QYRAHELGMKLAHGFEILCSKNGESSSD-QEPSVSSNPLWRGFLESLKKNGYFKGNLEGSARYKELMTSAESFFRQSVTRTHRPDIHNPGGEVLKVLQSASYSLEDLKKQEANLPPEDSDAWLDISPQELERLLAERGGRGGTGEEVQEEE-SGYSLIAVTQGMKNFINAMSSHEGAEIP---RSCLAEPFRFD-----------PDSVTSALDRLLGAKDDELDSDDFEDEDDDD--DDDDDEAVQSSVPQEQATGAETLDNLR-------------KYMDEMDQELQSTNIGKSFTQNNRSS--NKAEASKSSSSTSASELLEDEIQPLDVDLNLVTNLLESLSSQAGLAGPASNLLQSLGLHIPPDADQP---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W032-1", "uniprot_id": "ECD_DROME", "id": "Q9W032-1", "name": "Protein ecdysoneless", "aln": "MSKIPGSNLEFVREEDFVEYYIFPKIPDNVQDEGALRKLMLQIRNEISAIVREKSLERSYLWHKDEFQLQVRLGGAEERLLNEETNPEEEAELGDLPPHFHGVTHYGDNISDEWFVVYLLTEITRARGDCIARVSDSDGEFLLIEAADALPDWASPETCEQRVYLVGGHLQLLQNSAASS-----QDKPLTMAMAVQRIRMNPTLYRCSQEIQSCIDARLKEYQIAQPHFSIHRQVLELPHSAAQLLKQKPRLLSSAVRAFCERDSLDIKALRTMRYFPPEATRVRTNVRFTRCLYAMLSHQQYLPEKRLGWHLTDPVSEPERYKEQLLGLKLASGLEILATQAKR----VEGQQLEDLPAWRSYLRSLLSKGYFRDNIEGSAEYQELLNKAKVYFRGNQER-FRTASRAGAEILDLLLHPAEAASEELRDEENNLQPSDSDEWLNISAEDLDSMLQDRYGPKKLYKPNGQMNAEEFTKQLAEFLDRQSNYEGIEHRGLEEPELDSDDDEPPPQANGSTGLTAKVKKNPSMRKACQRNSVIQPEEPDSTHVRNFLDFVIPEDNWDSTSEMSDYADEDDMESNLNALSGGGSVFPLDRQIQSYMEQMDRELAQTSVGKSFHGKKKTAP----------QADEDDFDDIEDFEPININVNTLRNMMDSYQSQVGGAGPVSNLFSAMGVGMSAVEDKEQKDISESAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** *:* :* . : . * :. :: :. : .*:*::: *:* : *.:*.*: *:*.:***:.****:**::..**: : * : *.**:*******: **.* .*:.. :**:: *.* :: . * *: *:. : :. ..: :::.:: *: * : .:** :* . . :*.::* *::.** ** **.:*::* *.:: * *:: *: :.* **:**** * :* ::*::* *: *. :*: **:*** *:***.:: . : * * .:*.** :.**:. ::***.*:* : *: :*: . . . : :*.. :*: : :* *.*.* **::*.::*: :* : * : : . . : *.* * * . * : *. . :: : :* ** . . * :.: * : *. * .** .**:** * :.:** .:: . . . . .:::::* : *:::* .**.* ***.***: ::*: :. *: ", "identical_positions": 153, "similar_positions": 200, "identity": "21.73%" }, { "cls_id": "homologset.agr.FB:FBgn0000546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62685-1", "uniprot_id": "NR1H3_RAT", "id": "Q62685-1", "name": "Oxysterols receptor LXR-alpha", "aln": "----------------------MSLWLEAAVPDVSPDSATEL--------------------------------------WKTEPQDAG--DQGGNTCILREEARMPQSTGGALRIGLESS------------------------------------EPTALLPRAETLPEPTEL----------------------------------------------------------------------------------RPQKRKKGPAPKMLGNELCSVCGDKASAFHYNVLSCEGCKGFFRRSVIKG--ARYICHSGGHCPMDTYMRRKCQECRLRKCRHAGMREECVLSEEQIRLKKLKRQEEE-----------QAQATS----------------------VSPRVSSPPQVLP-----------QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYN--------------------------REDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSA-DRPNVQDQLQVERLQHTYVEALH----AYVSINHPHD---RLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0Y9-1", "uniprot_id": "NR1H3_MOUSE", "id": "Q9Z0Y9-1", "name": "Oxysterols receptor LXR-alpha", "aln": "----------------------MSLWLEASMPDVSPDSATEL--------------------------------------WKTEPQDAG--DQGGNTCILREEARMPQSTGVALGIGLESA------------------------------------EPTALLPRAETLPEPTEL----------------------------------------------------------------------------------RPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKG--ARYVCHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEE-----------QAQATS----------------------VSPRVSSPPQVLP-----------QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYN--------------------------REDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSA-DRPNVQDQLQVERLQHTYVEALH----AYVSINHPHD---PLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13133-1", "uniprot_id": "NR1H3_HUMAN", "id": "Q13133-1", "name": "Oxysterols receptor LXR-alpha", "aln": "----------------------MSLWLGAPVPDIPPDSAVEL--------------------------------------WKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEAA------------------------------------EPTALLTRAEPPSEPTEI----------------------------------------------------------------------------------RPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKG--AHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEE-----------QAHATS----------------------LPPRASSPPQILP-----------QLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYN--------------------------REDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSA-DRPNVQDQLQVERLQHTYVEALH----AYVSIHHPHD---RLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62755-1", "uniprot_id": "NR1H2_RAT", "id": "Q62755-1", "name": "Oxysterols receptor LXR-beta", "aln": "----------------------MSSP-TSSLDTPLPGNG------------------------------------------SPQPSTSS------TSPTIKEEGQE-----TDP-PPGSEG------------------------------------SSSAYIV---VILEPEDE----------------------------------------------------------------------------------PERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVHGGAGRYACRGSGTCQMDAFMRRKCQLCRLRKCKEAGMREQCVLSEEQIRKKKIQKQQQQ-----QPPPPTEPASGS----------------------SARPAASPGTSEASSQGSGEGEGIQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYS--------------------------KDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSA-DRPNVQEPSRVEALQQPYVEALL----SYTRIKRPQD---QLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60644-1", "uniprot_id": "NR1H2_MOUSE", "id": "Q60644-1", "name": "Oxysterols receptor LXR-beta", "aln": "----------------------MSSP-TSSLDTPVPGNG------------------------------------------SPQPSTSA------TSPTIKEEGQE-----TDP-PPGSEG------------------------------------SSSAYIV---VILEPEDE----------------------------------------------------------------------------------PERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVHGGAGRYACRGSGTCQMDAFMRRKCQLCRLRKCKEAGMREQCVLSEEQIRKKRIQKQQQQ-----QPPPPSEPAASS----------------------SGRPAASPGTSEASSQGSGEGEGIQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYS--------------------------KDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSA-DRPNVQEPSRVEALQQPYVEALL----SYTRIKRPQD---QLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55055-1", "uniprot_id": "NR1H2_HUMAN", "id": "P55055-1", "name": "Oxysterols receptor LXR-beta", "aln": "----------------------MSSPTTSSLDTPLPGNG------------------------------------------PPQPGAPS------SSPTVKEEGPEPWPGGPDPDVPGTDE------------------------------------ASSACSTDW-VIPDPEEE----------------------------------------------------------------------------------PERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSS----------------------ASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYS--------------------------KDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSA-DRPNVQEPGRVEALQQPYVEALL----SYTRIKRPQD---QLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34021-1", "uniprot_id": "ECR_DROME", "id": "P34021-1", "name": "Ecdysone receptor", "aln": "-----------MKRRWSNNGGFMRLPEESSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESGSFGGSNGHGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNLGALANGMLNGGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHHANGTPNGLIGVVGGGGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGYSANESCDAKKSKKGPAPRVQ-EELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKS--AVYCCKFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVS----FRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYT--------------------------RDSYKMAG-MADNIEDLLHFCRQMFSMKVDNVEYALLTAIVIFS--DRPGLEKAQLVEAIQSYYIDTLR----IYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQSHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSLTQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTAPGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNVSMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZFA7-1", "uniprot_id": "D3ZFA7_RAT", "id": "D3ZFA7-1", "name": "", "aln": "-----------MANTYVTTSDGYYLAEPTQYYDILPEQLHYQLCD-----------------------------------TDFQEPPYSQYSTAQFPPALQSPSLQSHFSTYGLEPQYSGGSWCG----------------------------LDTRE-SSQSTYVVVHDDEDEFP-------------------------------------------------------------------------------GTQRCRPTCSLRWKGQD-ELCMVCGDKASGYHYNALTCEGCKGFFRRSITKN--AVYSCKNGGHCEMDMYMRRKCPECRLKKCKAVGMLAECLLTEIQCKSKRLRKSFKHR----------PTLSSA-------------------IQVEDEGTDTKHVSSTSRSGKGAQDDMTLTAEERRLLNTIVTAHRKS---------MVPVGEISALLQEYSNPELSFLRLSEASILHANWLMKFTKGLPGFENLTAEDQTALQKESKTEVMFLHVAQLYGGRDSTSGSTVRPAKPSAGTLEVHNHRGDECVYSSENFFKEGYPSATLTGITREFIASLSYFYRRMRELNITDTEYALLTATTVLFS-DRPYLKNKQHVENLQEPVLQLL----FKYSKMYHPED---PQHFAHLIGRLTELRTLSHSHSEILSTWKTKDPRLVMLFSEKWDLHSLY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5A6-1", "uniprot_id": "E9Q5A6_MOUSE", "id": "E9Q5A6-1", "name": "", "aln": "-----------MANTYVATSDGYYLAEPTQYYDILPEQFHYQLCD-----------------------------------TDFQEPPYCQYSTAQFPPALQSPSLQSHFNTHGLDPQYSGGSWCG----------------------------LDARE-SGQSTYVVVHDDEDEFP-------------------------------------------------------------------------------GAQRCRATCSLRWKGQDDMLCMVCGDKASGYHYNALTCEGCKGFFRRSITKN--AVYSCKNGGHCEMDMYMRRKCQECRLKKCKAVGMLAECLLTEIQCKSKRLRKNFKHG----------PALYPA-------------------IQVEDEGADTKHVSSSTRSGKGVQDNMTLTQEEHRLLNTIVTVHQKS---------MIPLGETSKLLQEGSNPELSFLRLSEVSVLHIQGLMKFTKGLPGFENLTTEDQAALQKASKTEVMFLHVAQLYGGKDSTSGSTMRPAKPSAGTLEVHNPSADESVHSPENFLKEGYPSAPLTDITKEFIASLSYFYRRMSELHVSDTEYALLTATTVLFS-DRPCLKNKQHIENLQEPVLQLL----FKFSKMYHPED---PQHFAHLIGRLTELRTLSHSHSEILRMWKTKDPRLVMLFSEKWDLHSFS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BEQ0-1", "uniprot_id": "A0A8M2BEQ0_DANRE", "id": "A0A8M2BEQ0-1", "name": "", "aln": "MREGTDPEMSMSVSGYLSASDAFDITDHSQYYDVLVDPLSCSYQE-----------------------------------PDLQSPLYGQQ---PFSPVNVQFSMYGAQNVPACNPPYPYSHQCS----------------------------EYTCEPDMEVQSSTARASIVGLP-------------------------------------------------------------------------------VLKRPRMGHGARVKGQD-ELCVVCGDKASGYHYNALTCEGCKGFFRRSVTKK--AVYHCKSGGSCEMDMYMRRKCQDCRLRKCRAVGMLAECLLTEVQCQSKRLRKGSKHR----------GHNGSS-------------------ARAEDDYSESRSVSSTSRINTRVSS--GFSREQRCILNRIVEAFRRY---------IIQDNTHCRVPLWSS------LTNTHLTPPQTEKLLQFLRSVPGFDLLDSSDQNTLLSSASVEVMFLLLAQQFSENPTSVSTALYPAN-----LNNSNPDWGKTLESKN---GSSHRILTHSGLNDELLRSVVNFLHSMVTIAVTEAEYALLTATAVLCSADRPTLRAVGCVENLQEFVLELLSRVCCSCSQRTGAQD---PRRFARLLGRLTELRTLRHNH-------------LTLLPQQPWDLQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : ** ****:**.:***.*:***********: : * *: . * ** :***** ***:** .** :*::.* * *: .: :. . :: : :: :: : :. : : ::.* : :*.* : .** :* . . *:*:* :: :. : :. : : : * : * : : :.*:*** * :: *** :. :* :* :: * * :.::: *..**** : * : .: **:: ", "identical_positions": 75, "similar_positions": 89, "identity": "8.07%" }, { "cls_id": "homologset.agr.FB:FBgn0000557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VTE0-1", "uniprot_id": "EF1A3_HUMAN", "id": "Q5VTE0-1", "name": "Putative elongation factor 1-alpha-like 3", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGN----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FKVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHMAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68104-1", "uniprot_id": "EF1A1_HUMAN", "id": "P68104-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGN----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10126-1", "uniprot_id": "EF1A1_MOUSE", "id": "P10126-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGS----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62630-1", "uniprot_id": "EF1A1_RAT", "id": "P62630-1", "name": "Elongation factor 1-alpha 1", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYN------------------PDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGS----------------------------------ASGTTLLEALDCILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------VNVTTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDGPKFLK---------------------SGDAAIVDMVPGKPMCVESFSDYP------------------PLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62631-1", "uniprot_id": "EF1A2_MOUSE", "id": "P62631-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN------------------PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----------------------------------ASGVSLLEALDTILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRP-GMVVTFAP------------------------VNITTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKSLK---------------------SGDAAIVEMVPGKPMCVESFSQYP------------------PLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62632-1", "uniprot_id": "EF1A2_RAT", "id": "P62632-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN------------------PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----------------------------------ASGVSLLEALDTILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRP-GMVVTFAP------------------------VNITTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKSLK---------------------SGDAAIVEMVPGKPMCVESFSQYP------------------PLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05639-1", "uniprot_id": "EF1A2_HUMAN", "id": "Q05639-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGVGEFEAG------------------------ISKNG-----------QTREHALLAYTLGVKQLIVG--VNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYN------------------PATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----------------------------------ASGVSLLEALDTILPPT-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRP-GMVVTFAP------------------------VNITTEVKSVEMHHEALSEALPGDNVG------------------------------FNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKSLK---------------------SGDAAIVEMVPGKPMCVESFSQYP------------------PLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92005-1", "uniprot_id": "EF1A_DANRE", "id": "Q92005-1", "name": "Elongation factor 1-alpha", "aln": "--------------MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK------AERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAGGVGEFEAG------------------------ISKNG-----------QTREHALLAFTLGVKQLIVG--VNKMDSTEPPYSQARFEEITKEVSAYIKKIGYN------------------PASVAFVPISGWHGDNMLEASSNMGWFKGWKIERKEGN----------------------------------ASGTTLLDALDAILPPS-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKP-GMVVTFAP------------------------ANVTTEVKSVEMHHESLTEATPGDNVG------------------------------FNVKNVSVKDIRRGNVAGDSKNDPPMEAANFNAQVIILNHPGQISQGYAPVLDCHTAHIACKFAELKE---------------------------------------------------------------------------KIDRRSGKKLEDNPKALK---------------------SGDAAIVEMVPGKPMCVESFSTYP------------------PLGRFAVRDMRQTVAVGVIKSVEKKIGGAGKVTKSAQKAAKTK-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05303-1", "uniprot_id": "EF1A2_DROME", "id": "P05303-1", "name": "Elongation factor 1-alpha 2", "aln": "--------------MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLK------AERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKN----------------------------------------MITGTSQADCAVLIVAAGTGEFEAG------------------------ISKNG-----------QTREHALLAFTLGVKQLIVG--VNKMDSTEPPYSEARYEEIKKEVSSYIKKIGYN------------------PASVAFVPISGWHGDNMLEPSEKMPWFKGWSVERKEGK----------------------------------AEGKCLIDALDAILPPQ-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGLLKP-GMVVNFAP------------------------VNLVTEVKSVEMHHEALTEAMPGDNVG------------------------------FNVKNVSVKELRRGYVAGDSKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKE---------------------------------------------------------------------------KCDRRTGKTTETEPKAIK---------------------SGDAAIIVLVPSKPLCVESFQEFP------------------PLGRFAVRDMRQTVAVGVIKSVNFKETTSGKVTKAAEKAQKKK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02994-1", "uniprot_id": "EF1A_YEAST", "id": "P02994-1", "name": "Elongation factor 1-alpha", "aln": "--------------MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLK------AERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKN----------------------------------------MITGTSQADCAILIIAGGVGEFEAG------------------------ISKDG-----------QTREHALLAFTLGVRQLIVA--VNKMDSVK--WDESRFQEIVKETSNFIKKVGYN------------------PKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGV----------------------------------VKGKTLLEAIDAIEQPS-----------------RPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKP-GMVVTFAP------------------------AGVTTEVKSVEMHHEQLEQGVPGDNVG------------------------------FNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLE---------------------------------------------------------------------------KNDRRSGKKLEDHPKFLK---------------------SGDAALVKFVPSKPMCVEAFSEYP------------------PLGRFAVRDMRQTVAVGVIKSVD-KTEKAAKVTKAAQKAAKK--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M1NS15-1", "uniprot_id": "A0A8M1NS15_DANRE", "id": "A0A8M1NS15-1", "name": "Elongation factor 1-alpha", "aln": "--------------MAKERIHINLVIIGHVDGGKSTTTGHLVYKCGGIDHRTIEKYEKAATQMGKSSFKYAWVLDKLK------AERERGITIDISLLKFNTQKYTFTIIDAPGHRDFIKN----------------------------------------MITGTSQADAALLIVSAAKGEFEAG------------------------ISRNG-----------QTREHALLAYTLGVKQLVVC--VNKMDLTEPPFSQKRYDEVVRNVSVFVKKIGFE------------------IGAVPFIPISGWSGENMIVPSQKMQWFKGWKLKRKEGH----------------------------------CHGRTLLEVLDSLHPPV-----------------RNAGKPLRLPLQDVYKIGGVGTVPVGKIETGVLKP-GMVLTFSP------------------------AKLTAEVKSIEMHHQGLQTALPGHNVG------------------------------FNIKNVSVKNLRRGDVAGNAQQDPPSDVSSFIAQIIMLNHPGKIKVGYSPVLDCHTTHVSCRFAELRE---------------------------------------------------------------------------KLDRRSGRKLESWPQYLR---------------------SGDGATVKLVPNKPLCVESFFHYP------------------PLGRFAVRDLKQTVAVGVIKSVEKVDQAK----KTSQKAPVSK-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O88943-1", "uniprot_id": "KCNQ2_RAT", "id": "O88943-1", "name": "Potassium voltage-gated channel subfamily KQT member 2", "aln": "MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLVRIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVAWAGPRK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: ::..* :. ..: . *: . . .: :: . : . . . * . **: ** ** :: * ..: . ::: *. :: .. . :::: .. . : ** :.: * :. : *: :*. *:: : : : : :..:*: * :* *..: : * :. : . . . : * * :* * *.* . : : * * .* * . .: :* . . .:*. ::: . **.:: * :.: ..*: * : : . : : : *: . * *.: : . *: * : :*: * : ** . : :* * .:: :. .. *:** :::: :. : . ::: ", "identical_positions": 53, "similar_positions": 150, "identity": "6.22%" }, { "cls_id": "homologset.agr.FB:FBgn0000559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05197-1", "uniprot_id": "EF2_RAT", "id": "P05197-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58252-1", "uniprot_id": "EF2_MOUSE", "id": "P58252-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLSAAERAKKVEDMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13639-1", "uniprot_id": "EF2_HUMAN", "id": "P13639-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQS----KDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGE---GQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVM4-1", "uniprot_id": "A0A8N7UVM4_DANRE", "id": "A0A8N7UVM4-1", "name": "Elongation factor 2", "aln": "MVNFTVDQIREIMDKKSNIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLYYELSENDSAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPDELFQTFQRIVENVNVIISTYGEGEHGPMGNIMVDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGDKKKGDLPPTERAKKVEEMMKKLWGDKYFDPSCGKFSKTANNADGKKLPRTFCQLVLDPIFKVFDAIMNFKKEETQKLIEKLEVKLDAEDKEKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQRYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMVPTTDKGRFYAFGRVFSGIVSTGQKVRIMGPNFTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFENSHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIVAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSDESDQVCLSKSPNKHNRLYMKSRPFPDGLAEDIDKGDVSSRQELKLRARYLAEKYEWEVAEARKIWCFGPDGTGPNILVDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHADAIHRGGGQIIPTARRVLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPIFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPYDVNSKPSQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P3J5-1", "uniprot_id": "EF2_DANRE", "id": "Q6P3J5-1", "name": "Elongation factor 2b", "aln": "MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQERCITIKSTAISMYYELTENDLAFIKQC----KDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEDEGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGE---AQLSPADRCKKVEDMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDTEDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEAAMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSAESDQMCLSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEWEVTEARKIWCFGPDGTGPNMLVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHTDAIHRGGGQIIPTARRVLYACQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPKDAASKPCQIVADTRKRKGLKEGIPALDNFLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13060-1", "uniprot_id": "EF2_DROME", "id": "P13060-1", "name": "Eukaryotic translation elongation factor 2", "aln": "MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYND-DGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFK----------------IDVVKLMNRLWGENFFNAKTKKWQKQKE-ADNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKRKGLKEGLPDLSQYLDKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32324-1", "uniprot_id": "EF2_YEAST", "id": "P32324-1", "name": "Elongation factor 2", "aln": "MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQK----TDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYAD---EVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFG----------------VDKAKMMDRLWGDSFFNPKTKKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPEQAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****::* :*** *:********************* :****:.*:***:************ *********:: *: ::* *.: .: .********************************* :.*************:.*****::.:**:********:. ::*:*** * **.****::** : :*:: : * *:*.***********::**: * ** . .:*.:***: :*:. *: : .:.* *:* :****:::* ****::*:* *:**: : *. ::*: :**.***.*** :***.:***:**.:******.** ** * ***** ** .:.:*.***.. **:*:******:************:* * :* * ** ***:.****:**: *.***.:*****:**.*:* *.*** ****:****:****:** . :***:**********:**** **. ************:**** * :.******:**:*********:***.*** :*:* * ***:*****. **. .**********: :*: *: : :. *::* :..::::* *** :::.* ::*::***********.***:: * **.****:********.****:*** : *::*.**.:: *****:************* ** ** : *.*:: **::* ****** .*****.***::**:*..*.* ***:*.**************.:**. ******** *****. * .** : *:. :* :***:*:** :* .:: ***", "identical_positions": 514, "similar_positions": 200, "identity": "59.42%" }, { "cls_id": "homologset.agr.FB:FBgn0000560", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03372-1", "uniprot_id": "ESR1_HUMAN", "id": "P03372-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYM-CPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15370-1", "uniprot_id": "EGON_DROME", "id": "P15370-1", "name": "Protein embryonic gonad", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGDCVINKKNRTACKACRLRKCLLVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLAR----LQQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVG--TGIGGGASPSFLQAAK---------LHHQRQLKLDSRLSNTPSDSGASSAGDP-----------------NEDGVTSVLGGQIATPSSTNATSLPKLDLRHPNFPATSEPDADMQRQRHQELLEIFRSHSEPLYSSFAPFSHLPPVLLAAGVPQLPIFKDQFKAELLFPTTSSPELEEPIDLSFRSRADPASPMAHNSNSPSLSEPAAASHCLGESTNFVRKSTP--LDLTLVRSQTLTG---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * **.: *:*:*:*.::*****:** *: :. * ..:*.*:*:.*.:*:******* *** *.* * .**.. : * ::: * *.:. .:. *. ::: : *. :::* .: * * : * .* * *.: :* *.:.. ::: ** **.* :* : *. . * .* :*:..::. :**.* . .* :: : :... . : ** . * . .: ** . : * : : : : *. :*. .:. :. . . : . :: * *:: . . *.*: : :*. . ::. :** ", "identical_positions": 79, "similar_positions": 125, "identity": "13.26%" }, { "cls_id": "homologset.agr.FB:FBgn0000565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923M1-1", "uniprot_id": "MSRA_RAT", "id": "Q923M1-1", "name": "Mitochondrial peptide methionine sulfoxide reductase", "aln": "MLSASRRT--LQLLSSSIPVRMMGDSSSKVISAEEALPGRTESIPVAAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKF--WLLKGVYSTQVGFAGG------YTRNPTYKEVCSEKTGHAEVVRVVYRPEHVSFEELLKVFWENHDPTQGMRQGNDCGTQYRSAVYPTSAVQMEAALKSKEEYQKVLSKHGFGPITTDIREGQVFYYAEDYHQQY-----------------------LSKNPDGYCGLGG-----------------TGVSCPTAIKK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6Y7-1", "uniprot_id": "MSRA_MOUSE", "id": "Q9D6Y7-1", "name": "Mitochondrial peptide methionine sulfoxide reductase", "aln": "MLSASRRA--LQLLSSANPVRRMGDSASKVISAEEALPGRTEPIPVTAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKF--WVLKGVYSTQVGFAGG------HTRNPTYKEVCSEKTGHAEVVRVVYRPEHISFEELLKVFWENHDPTQGMRQGNDFGTQYRSAVYPTSAVQMEAALRSKEEYQKVLSKHNFGPITTDIREGQVFYYAEDYHQQY-----------------------LSKNPDGYCGLGG-----------------TGVSCPMAIKK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJ68-1", "uniprot_id": "MSRA_HUMAN", "id": "Q9UJ68-1", "name": "Mitochondrial peptide methionine sulfoxide reductase", "aln": "MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKF--WVLKGVYSTQVGFAGG------YTSNPTYKEVCSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQKVLSEHGFGPITTDIREGQTFYYAEDYHQQY-----------------------LSKNPNGYCGLGG-----------------TGVSCPVGIKK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40029-1", "uniprot_id": "MSRA_YEAST", "id": "P40029-1", "name": "Peptide methionine sulfoxide reductase", "aln": "--------------------------MSSLIS-----------------------KTIKYDPAKDKLITLACGCFWGTEHMYRKYLNDRIVDCKVGYANGEESKKDSPSSVSYKRVCGGDTDFAEVLQVSYNPKVITLRELTDFFFRIHDPTTSNSQGPDKGTQYRSGLFAHSDADLKELAKIKEEWQPKWGNK----IATVIEPIKNFYDAEEYHQLY-----------------------LDKNPQGYA-------------------------CPTHYLREM------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P08761-1", "uniprot_id": "MSRA_DROME", "id": "P08761-1", "name": "Peptide methionine sulfoxide reductase", "aln": "--------------------------MSLTITSSVTHPELKDLSTVRNEQKELNISPVHDVNVTKATATFGMGCFWGAESLYG--ATRGVLRTTVGYAGG------SSDLPTYRKMG----DHTEVLEIDYDPTVISFKELLDLFWNNHEYGLTTP----IKRQYASLILYHDEEQKQVAHASKLEEQERRAPE---IITTEIASKENFYPAEAYHQKYRLQGHKDLASSLNLSPKLLQTSYVATKLNGYLAGVGGIEQFKAEAETMGLTPTQRQYCYYHVEQNEGQGLYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: .:. .:. *****:* : : **:*.* . :*:.: ..:**:.: * * :::.** ..*:. *: ** * : . : : * : * . . *:* * : ** ** *** * : .: :** * : ", "identical_positions": 39, "similar_positions": 47, "identity": "13.4%" }, { "cls_id": "homologset.agr.FB:FBgn0000567", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9V2-1", "uniprot_id": "G3V9V2_RAT", "id": "G3V9V2-1", "name": "", "aln": "-----MAAVVQQNDLVFDFASNVMED--------------EQQLGDPAIFPAVIVEHVPGADILNGYAGLACVEEPNDMITESSLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAAEALLNMDSPGP-VLDEKRINNNIFSSSEDD-IVAPITHVSVTLDGIPEVMETQQVQE--------------SNADSPGASSPEQPKRKKGASLTCLGRRKTKPPRPDSPATTPNISVKKKSK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTSSRNQANRTRMSSSPGIKGG------------------------------------ATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPT-------QLFRTVHVVQPVQAIPE--EATITSTMQEEAAGSSVQGIRTIQASTQVPVVVSPGNQQLHTVTLQTVPLTTVIASTDPSSGAGPQKFILQAIPSSQPMTVLKENVLLQSQKPGSPPSIVFSPTPVQQVLTGSVQSLGNGAVSMASPPNFSATAPVVTFS------------RSSQLAAHPPGTVITSVIKAQETKTPKAEVEKK-AEGHLNGDPEEIEQQPQPYVMVVSSSNGFSSQVAITQNELLEPSSF----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60775-1", "uniprot_id": "ELF1_MOUSE", "id": "Q60775-1", "name": "ETS-related transcription factor Elf-1", "aln": "-----MAAVVQQNDLVFEFASNGMED--------------EQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNIDSPSPPVLDEKQINNNIFSSSEDD-IVAPITHVSVTLDGIPEVMETQQVQE--------------TNADSPGASSPEQRKRKKG--------RKTKPPRPDSPTTTPNISVKKKNK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQANRSRVSSSPGIKGG------------------------------------AATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPT-------QLFRTVHVVQPVQAVPE--EATIASTMQEEAANSSVPSIRTIQASTQVPVVVSPGNQQLHTVT---VPLTTVIASIDPSSGAGSQKFILQTIPSSQPMTVLKENVMLQSQKPGSP-SIVLSPTQVQQVLTSNVQSICNGAGSVASAPSFSATTPVVTFS------------RSSQLVAHPPGTVITSVIKAQETKTLKQEVEKK-AEDDLNEDAEKSAQQPQPYVMVLSSSNGFSSQVAVKQNELLEPNSF----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32519-1", "uniprot_id": "ELF1_HUMAN", "id": "P32519-1", "name": "ETS-related transcription factor Elf-1", "aln": "-----MAAVVQQNDLVFEFASNVMED--------------ERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGP-MLDEKRINNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQE--------------KYADSPGASSPEQPKRKKG--------RKTKPPRPDSPATTPNISVKKKNK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGG------------------------------------ATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPT-------QLFRTVHVVQPVQAVPEG-EAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSP-----------RSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQVAMKQNELLEPNSF----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZWM8-1", "uniprot_id": "D3ZWM8_RAT", "id": "D3ZWM8-1", "name": "", "aln": "-----MAIALQPSDLVFEFASNGMDD--------------IHQLEDPSVFPAVIVEQVPYPELVHLYSGLDLDEVHSGIIRDRTLCMTQDQILEG----SILLTDDNVSTSN----NSSSTEVLFNVATPSD-VLDEKQIFSTPEVLPDSNSVQAINLPNFLLSTPEPDDPKKTSDAG--------------DQKEYS-LEEVSREENLRKIGKSRKRNRKTKNNRSTSPVTDPSVPIRKKSK-----------------DGKGSTIYLWEFLLALLQDRNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKQKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESTETPEDSSQASTSSTPSTSTTRRPSSRVVTRASPEDKDSPSWEKPKVEHTGLQPSASLELGLSVDEEVPTTSTMIVSPLQSQAKPAKTVSTS-APSNIHLGVAP-VGPGST-------VTLQTIPLTTVLTNGPPAGTTAPAQLVLQSVPQVST-FKDTLTLQTSFPLNASLQENQVATQGTPLILSGLPQLLAGANHQSNPVTSQVIG-AGSAGPSSQPPGTVIAAFIRTSNGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQAHLQPLQSQALSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSSSGSLLV--TEPNMTTSGSLLTRSPTQAPFSPFNPTSLIKMEPHDI----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2U4-1", "uniprot_id": "ELF4_MOUSE", "id": "Q9Z2U4-1", "name": "ETS-related transcription factor Elf-4", "aln": "-----MAIALQPSDLVFEFASNGMDD--------------IHQLEDPSVFPAVIVEQVPYPELVHLCSGLDLDEVHNGIIRDRTLCMTQDQILEG----SILLTDDDVSTSN----NVSSTEVLFNVATPSD-VLDEKQIFSSPEVLSDSNSVQAINLPNFLLSTPEPDDLKKTSDAG--------------DQKEHSEEEKVSREENLRKMGKARKRNRKTKNNRSTSPVTDPSMPIRKKSK-----------------DGKGSTIYLWEFLLALLQDRNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKQKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDLVVIDDEEESPETPEDSSQASTSSTPSTSTIRRASSRVGTRASPEDKDNPPWEKPKVQHTGLQPSASLELGLSVDEEVPTTSTMLASPLQSQARLTKTVSSSPAPSNIHLGVAP-VGPGST-------VTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPQVST-FKDTFTLQTSFPLNTNLQENQVATQGAPLILSGLPQLLAGANPQSNPAPSQVIG-AGSAGPSSQPPGTVIAAFIRTSSGTSVPVVKEGPLRSSSYVQGVVTGAPVEGLLVPEETLRELLRDQGHLQPLPSQVLSRGSHNLSLVGNQTLSPPSHPTVGLTPVAELELSSGSGPLFV--TEP-------SVTRSPTQAPFSPFNPTSLIKMEPQDI----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99607-1", "uniprot_id": "ELF4_HUMAN", "id": "Q99607-1", "name": "ETS-related transcription factor Elf-4", "aln": "-----MAITLQPSDLIFEFASNGMDDD-------------IHQLEDPSVFPAVIVEQVPYPDLLHLYSGLELDDVHNGIITDGTLCMTQDQILEG----SFLLTDDNEATSH----TMSTAEVLLNMESPSD-ILDEKQIFSTSEMLPDSDPAPAVTLPNYLFPASEPDALNRAGDTS--------------DQEGHSLEEKASREESAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSK-----------------DGKGSTIYLWEFLLALLQDRNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKQKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDESSEATAAPPQASTASVASASTTRRTSSRVSSRSAPQGKGSSSWEKPKIQHVGLQPSASLELGPSLDEEIPTTSTMLVSPAEGQVKLTKAVSASSVPSNIHLGVAP-VGSGSA-------LTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPAAST-FKDTFTLQASFPLNASFQDSQVAAPGAPLILSGLPQLLAGANRPTNPAPPTVTG-AGPAGPSSQPPGTVIAAFIRTSGTTAAPRVKEGPLRSSSYVQGMVTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSRPTVGLTPVAELELSSGSGSLLM--AEPSVTTSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2K0-1", "uniprot_id": "A0A8M6Z2K0_DANRE", "id": "A0A8M6Z2K0-1", "name": "", "aln": "-----MTTVVQANELVFEFASNGMDE--------------INQLDDPSVFPAVIVEQVPAADLMQVYSGLEADEVTNGIMVDAIQDVVEENMMGD----VGLSVETPVSGGEDNMETIEAAEALLNMESPNN-ILDEKRMIHTYGNILETD-LSYISLR--------PEHLSNGMDVA--------------HDDETSSLDEVP-QKNFSKPAR-KTKVRKPRPARPCSPITNPSLPLKKKSK-----------------EGKGNTIYLWEFLLALLQDKNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPTDLVIIDEDD--GQGDDGGAGYGGHRAAPHGRVGRGSSRSQGRNT----------QVKTVKREMSPGLNSRNGKQAEQLLQTVHVLQPNQGAAVPAQTHSVRTINMPGSVPMVLTSGAQGGGP-------MTLQTLPLSSVLTNGDSSTHASPPRVILHTVPSTSPGGKDVLTIQTASLTTDSLHSQQLLVSTLSSSSGGVISTTPQQTASLNGITRLVTLNANGQPVVAQQPGTVIATVLKPSEYQSLQVKEE--ISDPQYFQSLVNNSPSFASFCKDEIAEGMAEMS-----YRTVIINTAGQELSQSLNGHSQLASSPSEGLTPVEELEVRGEVALHPE--PEAKELLESSQGLQELPVTMQIPASHFIQVKAEPTET----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6ACZ4-1", "uniprot_id": "A0A8I6ACZ4_RAT", "id": "A0A8I6ACZ4-1", "name": "", "aln": "---MDAAAP----------------------------------GATRQNAPGLLPRPSRSS--------------------------AGVTVLRP----LPVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRS------------PEFIHAAMRPDVITETVVEVSTEESEPM--------------DASPIPTSPD--SHEPMKK----KKVGRKPKTQQSPVSNGSPELGVKKKAR-----------------EGKGNTTYLWEFLLDLLQDKNTCPRYIKWT-QREKGIFKLVDSKAVSKLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGG-----------------------------------KNSSPMNCSRAEKGVTRVVNITSPAHD---ASSRCPTTTAP-------VSAAAAPRTVRVAMQVPVVMT-SLGQKISTVAVQSVNAGT--PLITST-SPATASSPKVVIQTVPTVMPASAENGDRITMQPAKIITIPATQLAQCQLQTKSNLTGSGSISLVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISAVIKGPEV---------------------KSE--AKKQEHDVKTLQLVEEKGADGNKTVT----------HVVVVSAPSAIALPVTMKTEGLVTCEK-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHC9-1", "uniprot_id": "ELF2_MOUSE", "id": "Q9JHC9-1", "name": "ETS-related transcription factor Elf-2", "aln": "---MASAVVDSGGSALELPSDGGENQE---------------GGDTGPDCPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENS----ETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCISTPEFIHAAMRPDVITETVVEVSTEESEPM--------------DASPIPTSPD--SHEPMKK----KKVGRKPKTQQSPVSNGSPELGIKKKAR-----------------EGKGNTTYLWEFLLDLLQDKNTCPRYIKWT-QREKGIFKLVDSKAVSKLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGG-----------------------------------KNSSPLNCSRAEKGVARVVNITSPTHD---GSSRSPTTTAP-------VSAAAAPRTVRVAMQVPVVMT-SLGQKISAVAVQSVNAGTGSPLITST-SPASASSPKVVIQTVPTVMPASTENGDRITMQPAKIITIPATQLAQCQLQAKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISALLKGPEG---------------------KSE--AKKQEHDVKTLQLVEEKGADGNKTVT----------HVVVVSAPSAIALPVTMKTEGLVTCEK-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15723-5", "uniprot_id": "ELF2_HUMAN", "id": "Q15723-5", "name": "ETS-related transcription factor Elf-2", "aln": "---MTSAVVDSGGTILELSSNGVENQE---------------ESEKVSEYPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENV----ETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPM--------------DTSPIPTSPD--SHEPMKK----KKVGRKPKTQQSPISNGSPELGIKKKPR-----------------EGKGNTTYLWEFLLDLLQDKNTCPRYIKWT-QREKGIFKLVDSKAVSKLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSG-----------------------------------KNSSPINCSRAEKGVARVVNITSPGHD---ASSRSPTTTAS-------VSATAAPRTVRVAMQVPVVMT-SLGQKISTVAVQSVNAGA--PLITST-SPTTATSPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSMPTQQASGQTPPRVISAVIKGPEV---------------------KSEAVAKKQEHDVKTLQLVEEKPADGNKTVT----------HVVVVSAPSAIALPVTMKTEGLVTCEK-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QIV0-1", "uniprot_id": "A0A2R8QIV0_DANRE", "id": "A0A2R8QIV0-1", "name": "", "aln": "---MTSVVLVDSGGAVVEYVTAVDDHLPEEGGVYEVEGEMEGEVEGDVEYPAVIVEPVPSARMEQGFAAQVLVYDDETYLMQGVAEEQEVETEVL----ETVEASVHG--VQCSDKTIEAAEALLHMDSPSSLRGDRSP-EVFVPPCVNTSEFLHAAMRPDVLTETVVEVSTEDMEPM--------------EVVTVIQEPEMLDTEPSKR----RKSGRKPKPHH--ISNGSPDMGIKKKSR-----------------EGKG-STYLWEFLLDLLQDKNTCPRYIKWT-QREKGIFKLVDSKAVSKLWGKHKN-----------KPDMNYETMGRALR-----------YYYQRGILAKVEGQRLVYQFKEMPKDIVVIDDDKCDPG-DDVIG---EKTYERVPPSSDTLLTDLSKTPTI-----------------------------------LRAADRTVLHPGSPKAKAALTATPVQRTVMVSTADPSHATI-------ISNANAPRTVRVAMQVPVVMTNSLGQKISTVAVQSTNPSLLTTAPTNTGSPTGTNAPKVLIQTMPTMVPATAENGDKITVQLAKIITIPATQLTQCQLQAKPG-TPTG-INLMGAPLTVRALTPMSVAPGTQVVRLAVPAQQSPVQAKTQVPVSIQTQTRIP--------------------ISVQTASTVQSVPLQIQIQQSQLSPKEKTTE----------SKPDITVLDNPTLKVPEEASNPQSEAES----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11536-1", "uniprot_id": "E74EB_DROME", "id": "P11536-1", "name": "Ecdysone-induced protein 74EF isoform B", "aln": "MIMVQHLVAASAHNFASQAAASLVNVSSSSSS------SSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKRYYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQ---HPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEIDCNGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . . .: .:: * .. : . . ** : : * : ::: : :.. : * ** *: .* :. . . . :.***: *: . :. *. :. :* * ** : *: : . *::: ::: . . : . . . . . ", "identical_positions": 20, "similar_positions": 63, "identity": "2.24%" }, { "cls_id": "homologset.agr.FB:FBgn0000568", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63503-1", "uniprot_id": "NR1D1_RAT", "id": "Q63503-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTLDSNNNTGGVITYIGSSGSS-PSRTSPESLYSDSSNGSFQSLTQGCPTYFPPS----PTGSLTQDPARSFGTVPPSLSDDSSPSSASSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKGTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQNAMN-----------------------------------------------------------------------------------------------------------------------------------------------------LANNQLSSLCPLETSPAPHPTSGSVGPSPPPAPAPTPLVGFSQFPQQLTPPR---------------------------------------------------------------------SP-SPEPTVEDVISQVARAHREIFTYAHDKLGTSPGNFNANHAS---GSPPATTPQCWESQGCPSTPNDNNLLAAQRHNEALNGLRQGPSSYPPTWPSGPAH-HSCHQPNSNGHR-----LCPTHVYSAPEGKAPANGLRQGNTKNVLLACPMNM---------YPHGRSGRTVQEIWEDFSMS---------FTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLNAMFDFSEKLNSLALTEEELGLFTAVVLVSADR---------------------SGMENSASVEQLQKTLLRALRALVLKNRPSETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UV55-1", "uniprot_id": "NR1D1_MOUSE", "id": "Q3UV55-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTLDSNNNTGGVITYIGSSGSS-PSRTSPESLYSDSSNGSFQSLTQGCPTYFPPS----PTGSLTQDPARSFGSAPPSLSDDSSPSSASSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKGTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-----------------------------------------------------------------------------------------------------------------------------------------------------LANNQLSSLCPLETSPTPHPTSGSMGPSPPPAPAPTPLVGFSQFPQQLTPPR---------------------------------------------------------------------SP-SPEPTMEDVISQVARAHREIFTYAHDKLGTSPGNFNANHAS---GSPSATTPHRWESQGCPSAPNDNNLLAAQRHNEALNGLRQGPSSYPPTWPSGPTH-HSCHQPNSNGHR-----LCPTHVYSAPEGEAPANSLRQGNTKNVLLACPMNM---------YPHGRSGRTVQEIWEDFSMS---------FTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLNAMFDFSEKLNSLALTEEELGLFTAVVLVSADR---------------------SGMENSASVEQLQETLLRALRALVLKNRPSETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20393-1", "uniprot_id": "NR1D1_HUMAN", "id": "P20393-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTLDSNNNTGGVITYIGSSGSS-PSRTSPESLYSDNSNGSFQSLTQGCPTYFPPS----PTGSLTQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSS-FYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-----------------------------------------------------------------------------------------------------------------------------------------------------LANNQLSSQCPLETSPTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPR---------------------------------------------------------------------SP-SPEPTVEDVISQVARAHREIFTYAHDKLGSSPGNFNANHAS---GSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSSYPPTWPPGPAH-HSCHQSNSNGHR-----LCPTHVYAAPEGKAPANSPRQGNSKNVLLACPMNM---------YPHGRSGRTVQEIWEDFSMS---------FTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADR---------------------SGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63504-1", "uniprot_id": "NR1D2_RAT", "id": "Q63504-1", "name": "Nuclear receptor subfamily 1 group D member 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELNAGGVIAYISSS----SSASSPASCHSEGSENSFQSSSSSVPSSPNSS----NCDANGNPKNTDVSSIDGVLKSDRTDCPVKTGKPGAPG----------------------MTKSHSGMTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKT----------------------------------------------------------------------------------------------------------------------------------------------------MMSTQFGGHLQSDTLAEPHEQS--------VPPAQEQLRPKPQLEQENIK-S---------------------------------------------------------------------TPPPSDFAKEEVIGMVTRAHKDTFLYNQEHRENSSESMPPHRGE---RIPRNVEQYNLNHDHRGGGLHSHFPCSESQQHLSGQYKGRNMMHYPNGHTVCISNGHCVNFSSAYPQR-----VCDRIPVGGCSQTESRNSYLCSTGGRMHLVCPMSK---------SPYVDPQKSGHEIWEEFSMS---------FTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLSSMFEFSEKLNGLQLSDEEMSLFTAVVLVSADR---------------------SGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60674-1", "uniprot_id": "NR1D2_MOUSE", "id": "Q60674-1", "name": "Nuclear receptor subfamily 1 group D member 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELNAGGVIAYISSS----SSASSPASCHSEGSENSFQSSSSSVPSSPNSS----NCDANGNPKNADISSIDGVLKSDRTDCPVKTGKTSAPG----------------------MTKSHSGMTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKT----------------------------------------------------------------------------------------------------------------------------------------------------MMNTQFSGHLQNDTLAEQHDQS--------ALPAQEQLRPKSQLEQENIK-N---------------------------------------------------------------------TP--SDFAKEEVIGMVTRAHKDTFLYNQEHRENSSESMPPQRGE---RIPRNMEQYNLNQDHRGSGIHNHFPCSERQQHLSGQYKGRNIMHYPNGHAVCIANGHCMNFSSAYTQR-----VCDRIPVGGCSQTENRNSYLCNTGGRMHLVCPMSK---------SPYVDPQKSGHEIWEEFSMS---------FTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLSSMFEFSEKLNALQLSDEEMSLFTAVVLVSADR---------------------SGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14995-1", "uniprot_id": "NR1D2_HUMAN", "id": "Q14995-1", "name": "Nuclear receptor subfamily 1 group D member 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVNAGGVIAYISSS----SSASSPASCHSEGSENSFQSSSSSVPSSPNSS----NSDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPG----------------------MTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKT----------------------------------------------------------------------------------------------------------------------------------------------------MMNSQFSGHLQNDTLVEHHEQT--------ALPAQEQLRPKPQLEQENIKSS---------------------------------------------------------------------SPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGE---RIPKNMEQYNLNHDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQR-----VCDRVPIDGFSQNENKNSYLCNTGGRMHLVCPMSK---------SPYVDPHKSGHEIWEEFSMS---------FTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADR---------------------SGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKS5-1", "uniprot_id": "A0A8M9PKS5_DANRE", "id": "A0A8M9PKS5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTANEACGSVILYAGSSGSSSPSPGSPSSGYQTQSPSSHSQPSSPEEVTFTEIGAFKQQGNAGSPNSPKLVFQFPEIYNNSTAGPNPHSYSHPIAG-------------------KRPCGFTGTFTKTGGMVLLCKVCGDIASGFHYGVHACEGCKGFFRRSIQQNINYKMCVKNENCLIMRMNRNRCQHCRFKKCLSVGMSRDAVRFGRIPKREKQRLLDEMQSYMNS----------------------------------------------------------------------------------------------------------------------------------------------------LNESSMG----METSPQHEPPP---------------------------------------------------------------------------------------------------SP--IENQSKEAIGALSRAYQDIFTNTQDHLNKRAGNNNISRSSSYQNSPSQDSNYPHANPLAGYHTTTHESFSGPVRCPVSTSESKCPVSLVDNNRYSYAPSFSQNHSQSSVNQPSQPTQAHYSSYTASQSQSPASCPFKLAAGSKVLACPLNA---------CPVSAPGVSSQQVWESFSQC---------FTPAVREVVEFAKGIPGFQELCQHDQVMLLKAGTFQVLMVRFCSLFNHKERSVTFLNGQTYPLGTLRGLGMGSLLDAMFEFSSKLSSLGLESDEMALFMAVVLVSADC---------------------SGISDMLAVEQLQEGLIRALRTLINRRHPDDNSLFSKLLLRLPDLRTLNNLHSDKLLAFRIDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13055-2", "uniprot_id": "E75BB_DROME", "id": "P13055-2", "name": "Ecdysone-induced protein 75B, isoform B", "aln": "MEAVQAAAAATSSGGSSGSVPGSGSGSASKLIKTEPIDFEMLHLEENERQQDIEREPSSSNSNSNSNSLTPQRYTHVQVQTVPPRQPTGLTTPGGTQKVILTPRVEYVQQRATSSTGGGMKHVYSQQQGTAASRSAPPETTALLTTTSGTPQIIITRTLPSNQHLSRRHSASPSALHHYQQQQPQRQQSPPPLHHQQQQQQQHVRVIRDGRLYDEATVVVAARRHSVSPPPLHHHSRSAPVSPVIARRGGAAAYMDQQYQQRQTPPLAPPPPPPPPPPPPPPPQQQQQQYISTGVPPPTAAARKFVVSTSTRHVNVIASNHFQQQQQQHQAQQHQQQHQQHQQHQQHVIASVSSSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNS-----SSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLVVFRTEHKELLRQQMWSMEDGNNSDGQQNKSPSGSWADAMDVEAAKSPLGSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCPLRNRANSGSSGDSGAAEMDIVGSHAHLTQNGLTITPIVRHQQQQQQQQQIGILNNAHSRNLNGGHAMCQQQQQHPQLHHHLTAGAARYRKLDSPTDSGIESGNEKNECKAVSSGGSSSCSSPRSSVDDALDCSDAAANHNQVVQHPQLSVVSVSPVRSPQP--STSSHLKRQIVEDMPVLKRVLQAPPLYDTNSLMDEAYKPHKKFRALRHREFETAEADASSSTSGSNSLSAGSPRQSPVPNSVATPPPSAASAAAGNPAQSQLHMHLTRSSPKASMASSHSVLAKSLMAEPRMTPEQMKRSDIIQNYLKRENSTAASSTTNGVGNRSPSSSSTPPPSAVQNQQRWGSSSVITTTCQQRQQSVSPHSNGSSSSSSSSSSSSSSSSSTSSNCSSSSASSCQYFQSPHSTSNGTSAPASSSSGSNSATPLLELQVDIADSAQPLNLSKKSPTPPPSKLHALVAAANAVQRYPTLSADVTVTASNGGPPSAAASPAPSSSPPASVGSPNPGLSAAVHKVMLEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .* *. * * .* .. . .. . . . . : .* .:**:**** *********:**************:*:*: * **::* *:*:****** **:***::************:***** *:* **. : : .. :. :: . :* :. . : : . . . . :: * :. * : :: * : . .:* :.:: :. ....:: ** *: ::...... .: . * : * : . : . ..*:. :. .*: .* . * . * .*.. *. . . .: :: *: . . * ::* *: * : . : :*: : : ", "identical_positions": 98, "similar_positions": 127, "identity": "6.91%" }, { "cls_id": "homologset.agr.FB:FBgn0000575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41138-1", "uniprot_id": "ID3_RAT", "id": "P41138-1", "name": "DNA-binding protein inhibitor ID-3", "aln": "------------------MKALSPVRGCYEAVCCLSERSLAIARGRG----KSPS---AEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPAPG----PPDGPHL---------PIQT------AELTPEL-VISKDK---RSFCH-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41133-1", "uniprot_id": "ID3_MOUSE", "id": "P41133-1", "name": "DNA-binding protein inhibitor ID-3", "aln": "------------------MKALSPVRGCYEAVCCLSERSLAIARGRG----KSPS---TEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPAPG----PPDGPHL---------PIQT------AELTPEL-VISKDK---RSFCH-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02535-1", "uniprot_id": "ID3_HUMAN", "id": "Q02535-1", "name": "DNA-binding protein inhibitor ID-3", "aln": "------------------MKALSPVRGCYEAVCCLSERSLAIARGRG----KGPA---AEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVL-AEPAPG----PPDGPHL---------PIQT------AELTPEL-VISNDK---RSFCH-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41135-1", "uniprot_id": "ID1_RAT", "id": "P41135-1", "name": "DNA-binding protein inhibitor ID-1", "aln": "MKVASSS-AAATAGPSCSLKAGRTA---GEVVLGLSEQSVAISRCAG---TRLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVA----TAGGRGL---------PVRAP----LSTLNGEISALAAEV---RSESEY--YIILLWETKATGGGCPP--YFSGA----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20067-1", "uniprot_id": "ID1_MOUSE", "id": "P20067-1", "name": "DNA-binding protein inhibitor ID-1", "aln": "MKVASGS-AAAAAGPSCSLKAGRTA---GEVVLGLSEQSVAISRCAG---TRLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVG----TTGGRGL---------PVRAP----LSTLNGEISALAAEV---RSESEY--YIILQWETEATGGGCPPSLLFRRIAI--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41134-1", "uniprot_id": "ID1_HUMAN", "id": "P41134-1", "name": "DNA-binding protein inhibitor ID-1", "aln": "MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVG----TPGGRGL---------PVRAP----LSTLNGEISALTAEA---ACVPAD--DRILCR----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PU21-1", "uniprot_id": "E9PU21_RAT", "id": "E9PU21-1", "name": "DNA-binding protein inhibitor ID-4", "aln": "MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAAR-CKAAEAAADEPALCLQCDMNDCYTRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLR---QPPPPAP---------PLHSAGACPVAPQRTPLTALNTDP---AGAVNKQGDSILCR----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41139-1", "uniprot_id": "ID4_MOUSE", "id": "P41139-1", "name": "DNA-binding protein inhibitor ID-4", "aln": "MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAAR-CKAAEAAADEPALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLR---QPPPPAP---------PLHPAGACPVAPPRTPLTALNTDP---AGAVNKQGDSILCR----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47928-1", "uniprot_id": "ID4_HUMAN", "id": "P47928-1", "name": "DNA-binding protein inhibitor ID-4", "aln": "MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAAR-CKAAEAAADEPALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLR---QPPPPAP---------PHHPAGTCPAAPPRTPLTALNTDP---AGAVNKQGDSILCR----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41137-1", "uniprot_id": "ID2_RAT", "id": "P41137-1", "name": "DNA-binding protein inhibitor ID-2", "aln": "------------------MKAFSPVR--SVRKNSLSDHSLGISRSKT----------PVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVTKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQ---------TSRTP----LTTLNTDISILSLQASEFPSELMSNDSKVLCG----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41136-1", "uniprot_id": "ID2_MOUSE", "id": "P41136-1", "name": "DNA-binding protein inhibitor ID-2", "aln": "------------------MKAFSPVR--SVRKNSLSDHSLGISRSKT----------PVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVTKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQ---------ASRTP----LTTLNTDISILSLQASEFPSELMSNDSKVLCG----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02363-1", "uniprot_id": "ID2_HUMAN", "id": "Q02363-1", "name": "DNA-binding protein inhibitor ID-2", "aln": "------------------MKAFSPVR--SVRKNSLSDHSLGISRSKT----------PVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQ---------ASRTP----LTTLNTDISILSLQASEFPSELMSNDSKALCG----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18491-1", "uniprot_id": "EMC_DROME", "id": "P18491-1", "name": "Protein extra-macrochaetae", "aln": "------------------MKSLTAVCQTGASGMPALNASGRIQRHPT------------HRGDGENAEMKMYLSKLKDLVPFMPKNRKLTKLEIIQHVIDYICDLQTELETHPEMGNFDAAAALTAVNGLHEDEDSDMEDADAEAEAEVDPDILAQRLNAEQPAKVSSPAARLPLTDRQTPNTLVAPAHPQQHQQQQQLQLQQQQLQSQQQLSNSLATPQNAEKDSRQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . :*: ::*: *** :* . :::::**:*:***** *** * :.. . : : : ", "identical_positions": 18, "similar_positions": 25, "identity": "7.86%" }, { "cls_id": "homologset.agr.FB:FBgn0000576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCK7-1", "uniprot_id": "D3ZCK7_RAT", "id": "D3ZCK7-1", "name": "", "aln": "---------------------------------MFQPAPKRCFTIESLVAKD-------------SP---------LPASRSEDP---------------IRP--AALSYAN-SSPINPFLNGFHSAAAAAAAGRGVYS-----------------------------------------------NPDLVF---------AEAVSHPPNPAVPVHPVPPP--------HALAAHPLPSSHSPHPLFASQQRD--------PSTFYP---------------------------------------------------------------------WLIHRYRYLG---------------HRFQGN-DTSPESFLLHN--------------------ALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04744-1", "uniprot_id": "EMX2_MOUSE", "id": "Q04744-1", "name": "Homeobox protein EMX2", "aln": "---------------------------------MFQPAPKRCFTIESLVAKD-------------SP---------LPASRSEDP---------------IRP--AALSYAN-SSPINPFLNGFHSAAAAAAAGRGVYS-----------------------------------------------NPDLVF---------AEAVSHPPNPAVPVHPVPPP--------HALAAHPLPSSHSPHPLFASQQRD--------PSTFYP---------------------------------------------------------------------WLIHRYRYLG---------------HRFQGN-DTSPESFLLHN--------------------ALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04743-1", "uniprot_id": "EMX2_HUMAN", "id": "Q04743-1", "name": "Homeobox protein EMX2", "aln": "---------------------------------MFQPAPKRCFTIESLVAKD-------------SP---------LPASRSEDP---------------IRP--AALSYAN-SSPINPFLNGFHS-AAAAAAGRGVYS-----------------------------------------------NPDLVF---------AEAVSHPPNPAVPVHPVPPP--------HALAAHPLPSSHSPHPLFASQQRD--------PSTFYP---------------------------------------------------------------------WLIHRYRYLG---------------HRFQGN-DTSPESFLLHN--------------------ALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZV90-1", "uniprot_id": "D3ZV90_RAT", "id": "D3ZV90-1", "name": "", "aln": "MCQAWCTPRTAAAPGHRAFPRAPLPHSSSAAATMFQPATKRGFTIESLVAKDGGTGG--------SPGSGGAGSHPLAVAASEEP---------------LRP--TALNYPHPSAAETAFVSGFPAAAAAG-ASRSLYG-----------------------------------------------GPELVF---------PEAMNHP---ALTVHPA-----------HQLGSSSL---QPPHSFFSAQHRD--------PLHFYP---------------------------------------------------------------------WVLR-NRFFG---------------HRFQAS-EVPQDGLLLHG--------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04742-1", "uniprot_id": "EMX1_MOUSE", "id": "Q04742-1", "name": "Homeobox protein EMX1", "aln": "---------------------------------MFQPAAKRGFTIESLVAKDGGTGG--------SPGSGGAGSHPLAVAASEEP---------------LRP--TALNYPHPSAAETAFVSGFPAAAAAG-AGRSLYG-----------------------------------------------GPELVF---------PEAMNHP---ALTVHPA-----------HQLGSSSL---QPPHSFFSAQHRD--------PLHFYP---------------------------------------------------------------------WVLR-NRFFG---------------HRFQAS-DVPQDGLLLHG--------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q804S6-1", "uniprot_id": "EMX1_DANRE", "id": "Q804S6-1", "name": "Homeobox protein EMX1", "aln": "---------------------------------MFSATGKRCFTIESLVAKE-------------SP------------ITLEDP---------------IRP--TALSY---SAPADSFLNGYQSP-----AGRALYP-----------------------------------------------NPELVF---------SETVNHA---PLSMHP------------HQLGSAPL---QHPH-FFGTQHRE--------PLNFYP---------------------------------------------------------------------WVLR-NRFFG---------------HRFQGN-DVSQDTLLLHG--------------------PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLANSLSLSETQVKVWFQNRRTKYKRQKLEEEGPECTQKKKGNHHINRWRIATKQTGSEDIDVMSDA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18488-1", "uniprot_id": "EMS_DROME", "id": "P18488-1", "name": "Homeotic protein empty spiracles", "aln": "-----------------MTKMIPPVPTAAAAVMMPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNVPGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQHLQAPHPHPHLSPAQQHVLHQHLLMQQQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDEEHELDASH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * *:***:*.:: .* : * : * .* * : : . : :: *::.. . ::.:. . ::* .: . ** *::: * ::* :: : :* :* . . : *: . ****************:**:***.*:******** ** .*.*:**************.** : *:* .::. *: . . : . * : *: ", "identical_positions": 77, "similar_positions": 68, "identity": "15.07%" }, { "cls_id": "homologset.agr.FB:FBgn0000577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8B1-1", "uniprot_id": "D3Z8B1_RAT", "id": "D3Z8B1-1", "name": "Homeobox protein engrailed-like", "aln": "----------------------------MEEKDSKSSETAA--EAQRQPEPSP------------------------------GGGSGGG--SSPSDSDTGRRRALMLPAVLQ--------------------------------------------APGNHQHPHRITN----FFIDNILRP-----------------------------------------EFGRRKDAGTCCAGAGGARGG----------------------------------------EGGAGSTEGGGG-ADGAEQILG--ARESRPNPACAPSAGGPLSGASGDPAADGEGGSKTLSLHGGAKKPGDPGGSLDGALKARGLGGGDLSVSSDSDSSQA-------------------------------------SATLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNP--NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09066-1", "uniprot_id": "HME2_MOUSE", "id": "P09066-1", "name": "Homeobox protein engrailed-2", "aln": "----------------------------MEEKDSKPSETAA--EAQRQPEPSS------------------------------GGGSGGG--SSPSDSDTGRRRALMLPEVLQ--------------------------------------------APGNHQHPHRITN----FFIDNILRP-----------------------------------------EFGRRKDAGTCCAGAGGARGG----------------------------------------EGGAGTTEGGGGGAGGAEQLLG--ARESRPNPACAPSAGGTLSAAAGDPAVDGEGGSKTLSLHGGAKKPGDPGGSLDGVLKARGLGGGDLSVSSDSDSSQA-------------------------------------SATLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNP--NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19622-1", "uniprot_id": "HME2_HUMAN", "id": "P19622-1", "name": "Homeobox protein engrailed-2", "aln": "----------------------------MEENDPKPGEAAAAVEGQRQPESSP------------------------------GGGSGGGGGSSPGEADTGRRRALMLPAVLQ--------------------------------------------APGNHQHPHRITN----FFIDNILRP-----------------------------------------EFGRRKDAGTCCAGAGGGRGGGAGG------------------------------------EGGASGAEGGGG-AGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQA-------------------------------------GANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNP--NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31533-1", "uniprot_id": "HME2B_DANRE", "id": "P31533-1", "name": "Homeobox protein engrailed-2b", "aln": "----------------------------MEEND----------HSNRDVERQ----------------------------------------DSGDESNR------AILPLLQ--------------------------------------------APGN-VLPHRITN----FYIDNILRP-----------------------------------------DFGRRKEG-SRRDEINIV-------------------------------------------------------------------ERENR--CPSAPGSG------QVAP-VSGEGTSSPRAVNASKKTDIST----DESLKSRAET-GDQCLSSDSDCSQR-------------------------------------CAAQAKQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKTP--TKEDKRPRTAFTAEQLQRLKNEFQNNRYLTEQRRQALAQELGLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHATVTKDDKSDSD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09015-1", "uniprot_id": "HME2A_DANRE", "id": "P09015-1", "name": "Homeobox protein engrailed-2a", "aln": "----------------------------MDENE----------QSARDVEQR----------------------------------------GASDESNS------AIRPLLQ--------------------------------------------APGNLQLPHRITN----FFIDNILRP-----------------------------------------DFGRKKEANITRYEDNHG-------------------------------------------------------------------ARENH--NPTGPSTG------QVGSTVPAEEASTTHTSSGGKEAEIES----EEPLKPRGEN-VDQCLGSESDSSQSN------------------------------------SNGQTGQGMLWPAWVYCTRYSDRPSSGPRSRKPKKKAA--SKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELGLNESQIKIWFQNKRAKIKKASGVKNGLAIHLMAQGLYNHSTTSKEDKSDSD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JT82-1", "uniprot_id": "A0A0G2JT82_RAT", "id": "A0A0G2JT82-1", "name": "Homeobox protein engrailed-like", "aln": "----------------------------MEEQQPEP-------KSQRDSGLGAVAA--------AAAVVAAAAPGGLSLSLSPGASGSSGS--DGDSVPVSPQPAPPSPPAAPCLPPLAHHPHLPPHPPPPPPPPPPPPP--------PQHLAAPAHQPQPAAQLHRTTN----FFIDNILRP-----------------------------------------DFGCKKEQPLPQLLVASAAAGGG---------------------------------------------AAGGGSRVERDRSQTGAGRDPVHSLGTRASGAASLLCAPDANCGPPDGSQPATAVGAGASKAGNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGG-SGGSAGSPGAQGAKFPEH-NPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN--EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09065-1", "uniprot_id": "HME1_MOUSE", "id": "P09065-1", "name": "Homeobox protein engrailed-1", "aln": "----------------------------MEEQQPEP-------KSQRDSGLG---------------AVAAAAPSGLSLSLSPGASGSSGS--DGDSVPVSPQPAPPSPPAAPCLPPLAHHPHLPPHPPPPPPPPPPP----------PQHLAAPAHQPQPAAQLHRTTN----FFIDNILRP-----------------------------------------DFGCKKEQPLPQLLVASAAAGGGA--------------------------------------------AAGGGSRVERDRGQTGAGRDPVHSLGTRASGAASLLCAPDANCGPPDGSQPATAVSAGASKAGNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGG-SGGNAGSPGAQGAKFPEH-NPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN--EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05925-1", "uniprot_id": "HME1_HUMAN", "id": "Q05925-1", "name": "Homeobox protein engrailed-1", "aln": "----------------------------MEEQQPEP-------KSQRDSALG---------------AAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPHLPPHPPPPPP----------------QHLAAPAHQPQPAAQLHRTTN----FFIDNILRP-----------------------------------------DFGCKKEQPPPQLLVAAAARGG-----------------------------------------------AGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGSQPA-AAGAGASKAGNPAAAAAAAAAAVA---AAAAAAAAKPSDTGGGGSGGGAGSPGAQGTKYPEHGNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN--EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04896-1", "uniprot_id": "HME1A_DANRE", "id": "Q04896-1", "name": "Homeobox protein engrailed-1a", "aln": "----------------------------MEDQRRGQ-------GEEEDDSGS-----------------------------------------------------LPSPPLLP---------------------------------------------------AHRNTD----FFIDNILRP-----------------------------------------DFGCKRER-----------------------------------------------------------------ERVTRD-----SGVRPTALPDSRSDGVSS---SASSTVSSPVSSRQSNKVEQGSSKSSSPS-------------------------------------------------------------------KDSQKQILWPAWVYCTRYSDRPSSGPRTRKLKKKNNNTESDDKRPRTAFTAEQLQRLKAEFQTSRYITEQRRQALARELGLNESQIKIWFQNKRAKIKKSSGFKNALAMQLMAQGLYNHSTTTIQEEEDN----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02836-1", "uniprot_id": "HMEN_DROME", "id": "P02836-1", "name": "Segmentation polarity homeobox protein engrailed", "aln": "MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRS------------ETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDK-TNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .: : :. * *.*** :*. ::: . . . .. : :******************* *: *: .::*******::*** *** **: .**:**:*** *: **.***:***************::* ** **::*********:*.. :.:. ", "identical_positions": 85, "similar_positions": 46, "identity": "15.04%" }, { "cls_id": "homologset.agr.FB:FBgn0000578", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08719-1", "uniprot_id": "EVL_RAT", "id": "O08719-1", "name": "Ena/VASP-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFAFEEFS-EQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEG--------------------------GPSTQRQ----VQNGPSPEEMDIQRRQVMEQ-------------------QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAT-------FSCSGPPPPPPPPV----------PPPPTGSTPPPPPPLPAGGAQGT---------------NHDESSASGLAAALAGAKLRRVQRPEDASGGSSP------SGTSKSDANRAS--SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWER-SNSVEKPVSSLLSRTPSVAKSPEA------KSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70429-1", "uniprot_id": "EVL_MOUSE", "id": "P70429-1", "name": "Ena/VASP-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-EQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQ-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEG--------------------------GPSTQRQ----VQNGPSPEEMDIQRRQVMEQ-------------------QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASTT-------LSCSGPPPPPPPPV----------PPPPTGSTPPPPPPLPAGGAQGT---------------NHDESSASGLAAALAGAKLRRVQRPEDASGGSSP------SGTSKSDANRAS--SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWER-SNSVEKPVSSLLSRTPSVAKSPEA------KSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI08-1", "uniprot_id": "EVL_HUMAN", "id": "Q9UI08-1", "name": "Ena/VASP-like protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-EQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEG--------------------------GPSSQRQ----VQNGPSPDEMDIQRRQVMEQH-----------------QQQRQESLERRTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAP-------VSCSGPPPPPPPPV----------PPPPTGATPPPPPPLPAGGAQGS---------------SHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSP------SGTSKSDANRAS--SGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWER-SNSVEKPVSSILSRTPSVAKSPEA------KSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B578-1", "uniprot_id": "A0A8M2B578_DANRE", "id": "A0A8M2B578-1", "name": "Ena/VASP-like protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAHSVQFCLP---QSHSDSGLHTSGCKIS-EQSICQARASVMIYDDTSKKWVPVKPGQQGFSRINIYHNTVNNSFRVVGVKLQ-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSTAMLFALNVLGSQDA--------------------------GPGAHR------QNGPVTDDGEAQRRQMMDQ-------------------HQMQMERERRTSGSAVSTLQFKVSASASQSETSLHD------------------------------------LRQYRANTLPPSYAHLNPAASSAHTAIPP------------------------------------------LQEGGYHMVDSPQKKAQQLSQLSTSLASAFSPVQQGVVPPPRNIKQIPLSPPTSQQDLKHATWSSAHMYAPLPAASPPVVMAVKQPGLPVALPLPPLNNGPKAPSNTSHLDPIMHLQQSSNGQAEECYPYQSPSGGPLHPHYPIQESSCPLPPL------------------------------------IGQPVQGPGLHPQQLYQTTPPFETTPTSHTTPKTSPSPVYQNAAAASTGPPVPPGHPSMLSAAPPVHPPTSASMVGPPAPPPPPG----------PPPPGPPPPGPPPPVTGPPPTPPPLP------------AGGGPAPSGLAAALAGAKLRKVQRPEESSSSSNN------SSNSKNDASRSSGGSGGGGEGLMQEMNALLARRRKAS---EKPED-----SQNEESNGSPS------SSRGQNSDPVKKPWER-ANSADK-----------------------------SSAVSRAKPLGSTSDA--ESFDFDRMKQEILEEVVRELQKVKEEIIDAIRRELLRIGST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F7EWC1-1", "uniprot_id": "F7EWC1_RAT", "id": "F7EWC1-1", "name": "Vasodilator-stimulated phosphoprotein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGGDPSTSEHRREEAPEHPPGPGPRSPQEAGLYGAGPRERLSRTWSQPRTPALPIRGAPGALPVGAPPALCAAMSNETVICSSRATVMLYDDSNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKLQPDQQVVINCAIIRGVKYNQATPIFHQWRDARQVWGLNFGSKEDAAQFAIGMANALEALEGGGP------------------------PPAPAPPA---WSTQNGPSPEELEQQKRQ--------------------------PEHLER----------------------------------------------------------------RVSNAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPPAPPAG----------------GPPPPPGPPPPPG---------PPPPPGLPPSGVSGAGHGTGVAPPPAPPLPT----AQGPSSGGSGAPGLAAAIAGAKLRKVSKQEE---ASGG------PLAPKAENSRG------TGGGLMEEMNAMLARRRKATQVG------------EKPPKDESASQEESEARIPAQSEPVRRPWEKNSTTLPRMKS--------------------------SSSVTTSEAHPSVP-SSSDDSDLERVKQELVEEVRKELQKMKEEIIEVFVQELRKRGSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70460-1", "uniprot_id": "VASP_MOUSE", "id": "P70460-1", "name": "Vasodilator-stimulated phosphoprotein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-ETVICSSRATVMLYDDSNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQVVINCAIIRGVKYNQATPIFHQWRDARQVWGLNFGSKEDAIQFATGMANALEALEGGGP------------------------PPAPAPPA---WSAQNGPSPEELEQQKRQ--------------------------PEHMER----------------------------------------------------------------RVSNAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPPAPPAG----------------GPPPPPGPPPPPG---------PPPPPGLPSSGVSGAGHGAGAAPPPAPPLPT----AQGPNSGGSGAPGLAAAIAGAKLRKVSKQEE---ASGG------PLAPKAENSRS------TGGGLMEEMNAMLARRRKATQVG------------EKPPKDESAS-EESEARLPAQSEPVRRPWEKNSTTLPRMKS--------------------------SSSVTTSEAHPSTP-CSSDDSDLERVKQELLEEVRKELQKMKEEIIEVFVQELRKRGSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50552-1", "uniprot_id": "VASP_HUMAN", "id": "P50552-1", "name": "Vasodilator-stimulated phosphoprotein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-ETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGP------------------------PPPPALPT---WSVPNGPSPEEVEQQKRQQPG----------------------PSEHIER----------------------------------------------------------------RVSNAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPPAPPAG----------------GPPPPPGPPPPPG---------PPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA----AQGPGGGGAGAPGLAAAIAGAKLRKVSKQEE---ASGG------PTAPKAESGRS------GGGGLMEEMNAMLARRRKATQVG------------EKTPKDESANQEEPEARVPAQSESVRRPWEKNSTTLPRMKS--------------------------SSSVTTSETQPCTP-SSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQELRKRGSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GMP8-1", "uniprot_id": "A0A8I6GMP8_RAT", "id": "A0A8I6GMP8-1", "name": "Protein enabled homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-EQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNTFRVVGRKIQ-DHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQEAAQSKVTATQDSTNLRCIFCVFYLGPTLPRQNSQLPAQVQNGPSQEEMEIQRRQLQEQQRQKELERERMERERLERERLERERLERERLEQEQLERQRQEREHV--ERLERER--LERLERERQDR---------------------ERERERLE-QLEREQVEWERERRMSNAAPSSDSSLYSAPLPEYSSCQPPSAPPPSYAKVISAPVSDAAPDYAVVTALPPTSTPPTPPLRHSATRFATSLGSAFHPVLPHYATVPRPLNRNSRPSSPVNTPSSQPPAAKSCAWPTSNFSPLPPSPPIMISSPPGKATGPRPVLPVCVSSPVPQMPPSPT-APNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPP-PPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAAAPASVETPLNPELGDSSASEPGLQAASQPAETPAPQGHVLGPPAPPPPPPLPSGP----AYAS-ALPPPPGPPPPPP-----LPSAGPPPPPPPPPPLPNQVPPP-PPPPPAPPLPASGIFSGSMSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPSGGNTVSVNLASSKTDSGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIET------EQKEDRSEDAEPVTSKAASTSTPEPTRKPWER-TNTMNGSKSPVISR---------------------PKSTPSSQ--PSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03173-1", "uniprot_id": "ENAH_MOUSE", "id": "Q03173-1", "name": "Protein enabled homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-EQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNTFRVVGRKIQ-DHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQEAAQSKVTATQDSTNLRCIFC----GPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMERERLERERLERERLERERLEQEQLERQRQEREHV--ERLERER--LERLERERQ-----------------------ERERERLE-QLEREQVEWERERRMSNAAPSSDSSLSSAPLPEYSSCQPPSAPPPSYAKVISAPVSDATPDYAVVTALPPTSTPPTPPLRHAATRFATSLGSAFHPVLPHYATVPRPLNKNSRPSSPVNTPSSQPPAAKSCAWPTSNFSPLPPSPPIMISSPPGKATGPRPVLPVCVSSPVPQMPPSPT-APNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPPLPPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAGAPASAETPLNPELGDSSASEPGLQAASQPAESPTPQGLVLGPPAPPPPPPLPSGP----AYAS-ALPPPPGPPPPPP-----LPSTGPPPPPPPPPPLPNQAPPP-PPPPPAPPLPASGIFSGSTSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPGGGNTGSVSLASSKADAGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIET------EQKEDRNEDAEPITAKAPSTSTPEPTRKPWER-TNTMNGSKSPVISR---------------------PKSTPSSQ--PSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8S7-1", "uniprot_id": "ENAH_HUMAN", "id": "Q8N8S7-1", "name": "Protein enabled homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS-EQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNTFRVVGRKIQ-DHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQET-----------------------GPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER-----ERQERER--QERLERQER--------------------------LERQE-RLER-QERLDRERQE----------------------------------------------------------------RQERERLER---------------LERERQERER---------QEQLEREQLEWERE----------RRISS-------------------------------------------------------------------------------------------------------------AAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGP----AQASVALPPPPGPPPPPP-----LPSTGPPPPPPPPP-LPNQVPPP-PPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIET------EQKEDKGEDSEPVTSKASSTSTPEPTRKPWER-TNTMNGSKSPVISRRDSPRKNQIVFDNRSYDSLHRPKSTPLSQ--PSANGVQTEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQELSKSNTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B449-1", "uniprot_id": "A0A8M3B449_DANRE", "id": "A0A8M3B449-1", "name": "Protein enabled homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQLQSAAQCKVSGFILNERCALSSKMEVHR-EQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNAFRVVGRKIQ-DHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQDA-----------------------GPPLPRQTP----QVQNGPSPEELEVQRRQLQELQRQKEKEQERLDRERQERERQEREMLERERTERERQDRERQDRERQERERLERERTEQERLERERQEQELLERERQERELIERERAEREKQEREQQE-QLDREQMDWERGRRISNAAFES--TLYTPPPPEYN------------KTTSSSPVSPSTPSYPPPAPLPSTATPPTPPLRHSASRFATSLGSAFHPVLPHYATVPRRQPAPPTPPPP---APAPPPPSKSVIWTANNFTPLPPSPPVMISSPPGKATGPRPMIAIPAPSPLSQKPPSPISAPNGPPTSLHFHTSSPVSGQPFSSPPTPPPPPPLYSPS------------------PTLPHLAPHVSCPSPQPAVLPSPSTAFPASAEHSVNSGLGDSCFSAP--EPPTHPADFPSQPDSAHGVPTPPPPPPLPPSSTV--TPTTAGPPPPPGPPPPPPPLPPTLTPTGPPPPPGPPPPPSGQAPPPAPPPPPAPPLPSGLFTPSPTTDENKGLSGLAAALAGAKLKKVPRSDEPLAPAAG--PAVSSGGAKPEASRGNGPLPGGG-GLMEEMSALLARRRRIAEKGSSPEP------EQKADDFEAT--VTPKVSACSTPDMPRKPWER-TNTMNGSKSPVIGRRDTPWRNQMG-TDKYYDSLNRPRSTPTPTGSISANGVPTEALDYDRLKQDILEEMRKELSKLKEELIDAIREELGKSNSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T4F7-4", "uniprot_id": "ENA_DROME", "id": "Q8T4F7-4", "name": "Protein enabled", "aln": "MAMKKLYAKTSFTSKKPSSAANSTPILAYHQQQHQQPGNGICEFQVVAPGHSGELMIRRSQSMHHKMSPPVGGLGSKSEYYSIEELQELDLLDYRHPMYHHYQQQELRQRYHEHEQLVLQLPKATSPKAGPIYEAPQRSQQQQDQMLYVPTAAQRDSSSSAAATSIASSSTLTSSPSPSSSSSLIFSTLRKCVSPSNPSVNPNQPSKTQPSKLGCSMSFSIRTTTATAATAAAANAATATLSTQQQQQQAQQQHKQHLYSNIHHYLIRQQQQKQHYTLQRRHNSVKDKFIGGITTIFAEQSIIGARASVMVYDDNQKKWVPSG-SSSGLSKVQIYHHQQNNTFRVVGRKLQ-DHEVVINCSILKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYEEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQ-------------------------QPQQQQFQQQQQQQQYQQMVQAGYAPSQQ--------------------------------------------YQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLPSSASANSVVYASQQQMLPQAHPQAPQAPTMPGPGYGG------------------------------------------------------------------------------------------------------PPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGG-----AAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKEDPQADLMGSLA-SQLQQIKLKKNKVTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPE-----AEVKKRPWEKSNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFG-------SASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :**:**:*** .*:*:* . .:*:::***: .:***** *:* *::**** :* :*:****** ******:: *:****.*:::* *: .* **: : . . * : * .* :: * *. . ** ** *** ... . ..* .::* ::*::: .: . .:*:** **:** : : . : . * . . . . * : :* ::: *: *: *:*:*:*:.: *: ", "identical_positions": 85, "similar_positions": 84, "identity": "7.24%" }, { "cls_id": "homologset.agr.FB:FBgn0000579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00925-1", "uniprot_id": "ENO2_YEAST", "id": "P00925-1", "name": "Enolase 2", "aln": "--------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDE------DKSKWMGKGVMNAVNNVNNVIAAAFV----------------------------------------------------------KANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAEKNVPLYQHLADLSKSKTSP--YVLPVPFLNVLNGG-SHAGGALALQEFMIAPTGAKTFAEAMRIGSEVYHNLKSLTK-----------------KRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVKIGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYP-IVSIEDPFAED---DWEAWSHFFKTAGIQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDKAVYAGENFHHGDKL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00924-1", "uniprot_id": "ENO1_YEAST", "id": "P00924-1", "name": "Enolase 1", "aln": "--------------------------------------------------------------------MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDG------DKSKWMGKGVLHAVKNVNDVIAPAFV----------------------------------------------------------KANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAEKNVPLYKHLADLSKSKTSP--YVLPVPFLNVLNGG-SHAGGALALQEFMIAPTGAKTFAEALRIGSEVYHNLKSLTK-----------------KRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KIKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYP-IVSIEDPFAED---DWEAWSHFFKTAGIQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDNAVFAGENFHHGDKL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX11-1", "uniprot_id": "ERR2_YEAST", "id": "P0CX11-1", "name": "Enolase-related protein 2", "aln": "--------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDG------NKSEWMGKGVTKAVSNVNSIIGPALI----------------------------------------------------------KSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDP--FVIPVPFFNVLNGG-AHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAK-----------------EQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEG--RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYP-IISLEDPYAED---DWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX10-1", "uniprot_id": "ERR1_YEAST", "id": "P0CX10-1", "name": "Enolase-related protein 1", "aln": "--------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDG------NKSEWMGKGVTKAVSNVNSIIGPALI----------------------------------------------------------KSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDP--FVIPVPFFNVLNGG-AHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAK-----------------EQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEG--RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYP-IISLEDPYAED---DWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42222-1", "uniprot_id": "ERR3_YEAST", "id": "P42222-1", "name": "Enolase-related protein 3", "aln": "--------------------------------------------------------------------MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDG------NKSEWMGKGVTKAVSNVNSIIGPALI----------------------------------------------------------KSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDP--FVIPVPFFNVLNGG-AHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAK-----------------EQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEG--RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYP-IISLEDPYAED---DWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P15429-1", "uniprot_id": "ENOB_RAT", "id": "P15429-1", "name": "Beta-enolase", "aln": "--------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDG------DKSRYLGKGVLKAVEHINKTLGPALL----------------------------------------------------------EKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD----LVLPVPAFNVINGG-SHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIK-----------------AKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD--KVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYP-VVSIEDPFDQD---DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21550-1", "uniprot_id": "ENOB_MOUSE", "id": "P21550-1", "name": "Beta-enolase", "aln": "--------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDG------DKARYLGKGVLKAVEHINKTLGPALL----------------------------------------------------------EKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD----LVLPVPAFNVINGG-SHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIK-----------------AKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD--KVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKNFIQNYP-VVSIEDPFDQD---DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13929-1", "uniprot_id": "ENOB_HUMAN", "id": "P13929-1", "name": "Beta-enolase", "aln": "--------------------------------------------------------------------MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDG------DKGRYLGKGVLKAVENINNTLGPALL----------------------------------------------------------QKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD----LILPVPAFNVINGG-SHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIK-----------------AKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD--KVVIGMDVAASEFYRNGKYDLDFKSP-DDPARHITGEKLGELYKSFIKNYP-VVSIEDPFDQD---DWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAIFAGRKFRNPKAK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17183-1", "uniprot_id": "ENOG_MOUSE", "id": "P17183-1", "name": "Gamma-enolase", "aln": "--------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDG------DKQRYLGKGVLKAVDHINSRIAPALI----------------------------------------------------------SSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGNSD----LILPVPAFNVINGG-SHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIK-----------------DKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTE--KMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRYITGDQLGALYQDFVRNYP-VVSIEDPFDQD---DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09104-1", "uniprot_id": "ENOG_HUMAN", "id": "P09104-1", "name": "Gamma-enolase", "aln": "--------------------------------------------------------------------MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDG------DKQRYLGKGVLKAVDHINSTIAPALI----------------------------------------------------------SSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSD----LILPVPAFNVINGG-SHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIK-----------------DKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTE--KIVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYP-VVSIEDPFDQD---DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07323-1", "uniprot_id": "ENOG_RAT", "id": "P07323-1", "name": "Gamma-enolase", "aln": "--------------------------------------------------------------------MSIQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDG------DKQRYLGKGVLKAVDHINSTIAPALI----------------------------------------------------------SSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAEKDLPLYRHIAQLAGNSD----LILPVPAFNVINGG-SHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIK-----------------DKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTE--KMVIGMDVAASEFYRDGKYDLDFKSP-ADPSRCITGDQLGALYQDFVRNYP-VVSIEDPFDQD---DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGEEARFAGHNFRNPSVL----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04764-1", "uniprot_id": "ENOA_RAT", "id": "P04764-1", "name": "Alpha-enolase", "aln": "--------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDN------DKTRFMGKGVSKAVEHINKTIAPALV----------------------------------------------------------SKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE----VILPVPAFNVINGG-SHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIK-----------------EKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTD--QVVIGMDVAASEFYRAGKYDLDFKSP-DDASRYITPDQLADLYKSFIKDYP-VVSIEDPFDQD---DWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5YC61-1", "uniprot_id": "A0A8I5YC61_RAT", "id": "A0A8I5YC61-1", "name": "phosphopyruvate hydratase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MLFPVGE----------------------------------------------------------SKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE----VILPVPAFNVINGG-SHAGHKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIK-----------------EKYGKDATNVGDEGGFAPNNLENKDALELLKSAIAKAGSTD--QVVIGMDVAASEFYRAGKYDLDFKSP-DDASWYITPDQLADLYKSFIKDYP-VVSIEDPFDQD---DWD------------VVGDDLTVTSPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17182-1", "uniprot_id": "ENOA_MOUSE", "id": "P17182-1", "name": "Alpha-enolase", "aln": "--------------------------------------------------------------------MSILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDN------DKTRFMGKGVSQAVEHINKTIAPALV----------------------------------------------------------SKKVNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPE----VILPVPAFNVINGG-SHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIK-----------------EKYGKDATNVGDEGGFAPNILENKEALELLKTAIAKAGYTD--QVVIGMDVAASEFYRSGKYDLDFKSP-DDPSRYITPDQLADLYKSFVQNYP-VVSIEDPFDQD---DWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06733-1", "uniprot_id": "ENOA_HUMAN", "id": "P06733-1", "name": "Alpha-enolase", "aln": "--------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDN------DKTRYMGKGVSKAVEHINKTIAPALV----------------------------------------------------------SKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSE----VILPVPAFNVINGG-SHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIK-----------------EKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTD--KVVIGMDVAASEFFRSGKYDLDFKSP-DDPSRYISPDQLADLYKSFIKDYP-VVSIEDPFDQD---DWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1X2-1", "uniprot_id": "A0A2R8Q1X2_DANRE", "id": "A0A2R8Q1X2-1", "name": "phosphopyruvate hydratase", "aln": "--------------------------------------------------------------------MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDN------DKTRYLGKGVKRAVKYVNEFLAPALC----------------------------------------------------------NQNVSVLEQEKIDKLMLDMDGTDNKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPE----VILPVPAFNVINGG-SHAGNKLAMQEFMILPVGASNFKEAMRIGAEVYHNLKNVIK-----------------EKYGKDATNVGDEGGFAPNILENKEALELLKNAISKAGYTD--KIVIGMDVAASEFYKGGKYDLDFKSP-DDPSRYISPDKLADLYKSFVKDYP-VVSIEDPFDQD---DWEAWTNFTATTNIQVVGDDLTVTNPKRIAKAVSDKACNCLLLKVNQIGSVTESLQACKMAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGDKARFAGKNFRKPI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15007-1", "uniprot_id": "ENO_DROME", "id": "P15007-1", "name": "Enolase", "aln": "-MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDN------DKANYHGKSVLKAVGHVNDTLGPELI----------------------------------------------------------KANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKE----IILPVPAFNVINGG-SHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIK-----------------AKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTG--KIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFP-IVSIEDPFDQD---HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NNW6-3", "uniprot_id": "ENO4_HUMAN", "id": "A6NNW6-3", "name": "Enolase 4", "aln": "MEEEGGGRSCGTTR---ELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTICKIVGKDVLDGLGLPTLQVDIFCTIQNFPKNVCSVVISTHFEVHENALP--ELAKAEEAERASAVSTAVQWVNSTITHELQGMAPSDQAEVDHLLRIFFASKVQEDKGRKELEKSLEYSTVPTPLPPVPPPPPPPPPTKKKGQKPGRKDTITEKPIAPAEPVEPVLSGSMAIGAVSLAVAKACAMLLNKPLYLNIALLKHNQEQPTTLSMPLLMVSLVSCGKSSSGKLNLMKEVICIPHPELTTKQGVEMLMEMQKHINKIIEMPSPPKAETKKGHDGSKRGQQQITGKMSHLGCLTINCDSIEQPLLLIQEICANLGLELGTNLHLAINCAGHELMDYNKGKYEVIMG-----TYKNAAEMVDLYVDLINKYPSIIALIDPFRKEDSEQWDSIYHALGSRCYIIAGTASKSISKLLEQGNISIPKSNGLIIKHTNQTTMSDLVEITNLIDSKKHITVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFKEEHTFFYFNEEAEKAAEALEAAAAREPLVPTFPTQGVEESAETGASSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRT2-1", "uniprot_id": "D3ZRT2_RAT", "id": "D3ZRT2-1", "name": "Enolase 4", "aln": "MGEEGGGRSGGISR---DLLKLKQQAMAYYQENDVPRKLEELLNSTFYLQPADVYGHLANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICSVAIPTHSEVVENALP--EMVDADEAERQQAVSKAVRWINQFITEELWGLIPSNQAEVDRRLRIFFEHKVQADKDRKELERSQE-EPVPMTLP-VILPPPPPPPSKKKGQKAGRRDTLLEKPIFPPEPPEPVLHGSMAIGAVSLAVAKTSATLAGTPLYLTLALLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVMCIPSPGLTTKQGIELLLEIQKQVNRAMETLPPPKPETKKGHNGGKRSQPPITGRASHLGCLTINYDTIEQPLLLIQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVG-----TYKSAAEMVELYVDLINKYPSIIALIDPFRKEDSEQWDSLYAAVASRCYLIAGAASRSVSRLLEDRNISLLKYHGLIIKHTNQTTMSDLVEITHLINGKKHLAVFGSTDSESSDDSLVDLAVGLGARFIKLGGLSRGERMTKYNRLLAIEEELIQSGAWGFSEEHNFSFFQEDATTT----TAEETLEPLDSIFPTEVIEESAKT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08BC6-1", "uniprot_id": "ENO4_DANRE", "id": "Q08BC6-1", "name": "Enolase 4", "aln": "MSYKGFPSHSKVSKEDQEFYDLKNKAAEYYRSNGVPQKIESVLNEMFWQKPDDIYGYLANYFSGLSYTPVISKITGKEVFDGRGLTAVQAEVHCIIRNEEKMVCGAVMDGSFDGLPDGVESGEMLSNGDLQH-LSITMALKWIRENFSPVLRGFNPTDQTNVDKILSDFAMARYLEHKDSLIREKEEELRNEAMSEAPPQATPTSAPAKDKKGNDKGKKGNITENPLPPAEPPVPRLPGATAVGAVSLAVAKTAAELLGTPLYRHITAVRDPQAQK-EMQLPVPIITIMSCGKNSAGKLNLLEEIILMPSSSLRVREVIGMGLDLQCEMRRILN--------------GSTYKALPVG--VSDEGALQVGFDRPEQALDLLAEACANLALPLGSDLHLAVNCAAHSLMDYSRGKYEVMSG-----CHKSPDELVDIYEGLINKYPAIRSLIDPFRKEDVGQWERLASVIGQSCCLLADAASNLCPRWREAKPLPP-GATKAIIRHHSDMTISDLIQS--IAEHKETILAAG-----SGDASMVDLAVGSGVSFLKLGGLRGAKRMDKYNRLMAIEEE--QEGIAGAGEINQPVSFESESGWN--------------------SLTVSAK------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . : . *: *: .**:...:: * .** :: : :*: .::. * .* ::*. * : : : :: :. : .. * . . .: * :: . . :.:: * : .: . :. :: * ::. :* : :: **: :: .* : ::: . :::: : . : * : **.** :* *. .:*: * *.:: *** . . ", "identical_positions": 33, "similar_positions": 95, "identity": "5.2%" }, { "cls_id": "homologset.agr.FB:FBgn0000581", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADG5-1", "uniprot_id": "D4ADG5_RAT", "id": "D4ADG5-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPL---QFEIMIDRLEKASSN------------QLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS-EKELY----------------------------------------------------ASPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPP---QPTPETVPVINKSDIKQYDFQS----------SDEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSEL-----ADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLS-SSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEE-------CTSRKPGQTVSSKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGIAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AJU0-1", "uniprot_id": "A0A8I6AJU0_RAT", "id": "A0A8I6AJU0-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKNESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEVKPL---QFEIMIDRLEKASSN------------QLVTLQEAELLLNEDDYLIKAVYDYWVRKSKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS-EKELY----------------------------------------------------ASPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPP---QPTPETVPVINKSDIKQYDFQS----------SDEDEFPQVPSPSSEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCKSSEL-----ADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLS-SSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEE-------YTSRKPGQTVSSKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGIAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0I4-1", "uniprot_id": "EPC2_MOUSE", "id": "Q8C0I4-1", "name": "Enhancer of polycomb homolog 2", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPL---QFEIMIDRLEKASSN------------QLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS-EKELY----------------------------------------------------ASPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAGIAPQ---QPTPETLPVINKSDIKQYDFQS----------SDEDEFPQVLSPASEAEEENDPDGSCAFRRRAGCQYYAPRLDQANNHMCENSEL-----ADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGFS-SSSQTIDFSSNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQDIDSEE-------CTSRKPGQTVSSKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLVQMQRQQLAQLHQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGLAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q52LR7-1", "uniprot_id": "EPC2_HUMAN", "id": "Q52LR7-1", "name": "Enhancer of polycomb homolog 2", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPL---QFEIMIDRLEKASSN------------QLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRS-EKELY----------------------------------------------------ATPAT-LHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQ---QPTPETLPVINKSDIKQYDFHS----------SDEDEFPQVLSPVSEPEEENDPDGPCAFRRRAGCQYYAPRLDQAN-HSCENSEL-----ADLDKLRYRHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNSFS-SSSQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDSEE-------CTSRKPGQTVNNKRVSAASVALLNTSKNGISVTG----GITEEQFQTHQQQLVQMQRQQLAQLQQKQQSQHSSQQTHPKAQGS---------------------------------------------------------------------------STSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNTGHNNINGVVQPSGTSKTLYSTNMALS----SSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLT-NAVHLNNVSVVSPVN-------VHINTRTSAPSPTALKLATVAASMDRVPKVTP-SSAISSI-----ARENHEPERLGLNGIAETTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C9X6-1", "uniprot_id": "EPC1_MOUSE", "id": "Q8C9X6-1", "name": "Enhancer of polycomb homolog 1", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFRMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPL---QFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGSSLIPLVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY----------------------------------------------------AIPIIPITNSSQFKHQDATDSKEFKVNKQDKA-DLIRPKRKYEKKPKVLPPSAAA-PQQQSPAALPGFSAKDLNQYDFPS----------SDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVPQ-RCLGFARRRVGRGGRVVLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSEPNTSDRSSS-----KDLSQILVDIKSCRWRHFRPRTPSLPDSDSGE-------LSSRKLHRSISRAGAAQPGAHTCSTSTQNRSSSGSAHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQQANSSSSAAAQ----------------------------------------------------------------------------------QGFVSKTLDSASAQFAASALMTSEQLLGFK-VKDDVVLGLGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSSLSHQVTAASSATTQVLFGNNIRLTVPSSVPTVNSVTPINARHIPRTLSAVPPSALKLAAAAN--CQVSKVPS-SSSVDSV-----PRENHESEKPALNNIADNTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G2P8-1", "uniprot_id": "A0A8I6G2P8_RAT", "id": "A0A8I6G2P8-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPV---QFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY----------------------------------------------------AIPIIPITNSSQFKHQDVTDAKEFKVNKQDKA-DLIRPKRKYEKKPKVLPSSAAA-PQQPSPAALPGFSAKDLNQYDFPS----------SDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVPQ-RCLGFARRRVGRGGRVLLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSETNTSDRPSS-----KDLSQILVDIKSCRWRHFRPRTPSLPDSDSGE-------LSSRKLHRSISRAGPAQPGAHTCSASTQSRSSSGSTHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQ-ANSSSSTAAP----------------------------------------------------------------------------------QGFVSKTLDSASAQFAASALMTSEQLMGFK-MKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSALSHQVTAANSATTQVLFGNNIRLTVPSSVPTVNSIAPINARHIPRTLSAVPPSALKLAAAAN--CQVSKVPS-SSSVDSV-----PRENHESEKPALNNIADNTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2F5-1", "uniprot_id": "EPC1_HUMAN", "id": "Q9H2F5-1", "name": "Enhancer of polycomb homolog 1", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPL---QFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKNCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYNGEIMSEVMAQRQPMKPTY----------------------------------------------------AIPIIPITNSSQFKHQEAMDVKEFKVNKQDKA-DLIRPKRKYEKKPKVLPSSAAATPQQTSPAALPVFNAKDLNQYDFPS----------SDEEPLSQVLSGSSEAEEDNDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVPQ-RCIGFARRRVGRGGRVLLDRAHSDYDSVFHHLDLEMLSSPQHSPVNQFANTSETNTSDKSFS-----KDLSQILVNIKSCRWRHFRPRTPSLHDSDNDE-------LSCRKLYRSINRTGTAQPGTQTCSTSTQSKSSSGSAHFAFTAEQYQQHQQQLALMQKQQLAQIQQQQANSNSSTNTSQNLASNQQKS------------------------------------------------------------GFRLNIQGLERTLQGFVSKTLDSASAQFAASALVTSEQLMGFK-MKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSALLQPSNITQTSSSHSALSHQVTAANSATTQVLIGNNIRLTVPSSVATVNSIAPINARHIPRTLSAVPSSALKLAAAAN--CQVSKVPS-SSSVDSV-----PRENHESEKPALNNIADNTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U369-1", "uniprot_id": "A0AB32U369_DANRE", "id": "A0AB32U369-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESLYPGDFKMPKQLIHIQPFSLDTEQPDYDLDSEDEAFVNKLKKKMDVGAL---QFEEMIDRLEKGSGQQMLLSKATCIALKPVTLQEAKLLLKEDDELIKEVFEYWSKKRKTCQSGSLIPVVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIVEKRNNMSDFGGEVMAEVLAQRALEKP------------------------------------------------------VIPLIPITNSTQYRHTEHD--RDYKI-KMDKP-EVVRQKRKYEKKPKPLPLAGSV------HSGPSVFNTKDLNQYDFPS----------SDDEPFSQMFSGSSEVEEENDPDGVFGFRRRTGCQYHSARSGPVSGWPWSDPAE-----GGVADVRYRYSLTTLTVPR-RCLGLARRRVGRGGRVLLDRAHSEWDTVYHGLDPDSPAFPSLSPTQQQPSTDTSHTSTDTSAPSATPPDLTQILLNIKACRWRHFKPRTAPPDDPDNPEH------WSTRRPRRGFLIRPIRTLQTQRGPASIRPPPPPPTP--AFTAEQYQQHQEQLVLMQKQQLEQVQQHQQTGSSAVTNNP----------------------------------------------------------------------------------QSLVSKTIDAASAQFAASALVTHEQLLALK-SKDE---GVGVNGVVSASGVYKGLHHTSSAVSSILPSVGSTS-TSCPSPTIATTTNNGTSSANHHVGPAGPAPGQALMGGAVRVSVPSPAGTLS------VRQLQRQLT-VPASALKLAANAN--RPLPKVTTGSTTLDMG-----PRENHDQEKPPLNSLTENTVAMEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFP2-1", "uniprot_id": "A0A0B4KFP2_DROME", "id": "A0A0B4KFP2-1", "name": "Enhancer of polycomb-like protein", "aln": "-------------------------------------------------MSKLSFRARHLDPSKQMPIYLAEELPDLPEYSAINRAVPQMPSGMEKEEESEHHLQRAICTGLIIPTP--------EVLQTDQPFYDAYYPPDYKMPRQMIHMQPLGLDTEVPDYDMDSADEDWLSQQ-QRLELTEL---KFEQMMDRLEKSSGQ------------TVVTLNEAKSLLNQDDETSISVYDYWLNKRLKMQHP-LILTVKTESRPGASSNNPYLAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLQRATTILEMVRRREETKRDHLKMTVNIFEKRVEMRDFNGAVYSELNSQYKNTRPAYNPLYTNQYSQGAAAVGTAGAILAALPTGLLPGGAGAAGNANVFGSASQYLNSSNLTMDAISGSGNGNSSRKEKRPYKKRKHKLPRDKQQHQQQQTQQHQQQQYLPASGGAGVSPAHHLPHHLHHLSRQQSASPAANDSIADSEEEDYFGAGAQNGNKLGSESEEETPFAFRRRSSCVYLPTR-QRDGRYPWDSADEDMAPSGACSDAKYRYTLTSLNYPRPRCIGFARRRLGRGGRILLDRATTNFDDFWSQLDYTVMESVTVNKCRDKIKQRDPDQLCKPSSP----PTVVDLVPAGKPVDGEHPVPELIKEEPSSDTEKPVAATESGRESKERELEEKFENDVDDEFVASDDENVSRLGIYSSAVTLPQSCADLRQKRRRLRRKKQQLRELNAAKRLKRSSEAVATAEDVQLEDEDTKPDLRPLPRAYLQRLALILGQKLKVEEDDNTEVSENVAPELLEMNDPEQLQPPRANHQQHHRSNHNNNNNTVLNNNNSSSSNVMNKDVSISEKINVIKQEAEELVGGKCEDQPVASTSAAAAAARAAEAAAAAEAASSTTTLAAPNPGPSLEEVAKTIKREMIDADDSNEPLSSIRT-AAVMLSTQTSVSELMDDEAEDDVNLAQLSSIIRHTAVKKELEAQQHQQQVQHEQMQAARKMEEDEAAPCLNQLPDVIRLRNIRNSQVHARPKDLFVQAPVDEEFNADYMGGLSPTSSQRLDICNELLSEIRRDWLHFRPKTPTDELSDSQDCEVGKTCDSHAVDWTQDTPISVELNRLGKREAEESDSSSYFLSSGFKYRDLESDAQLLQTVQAQDYARGSSKSPNCSGSGSGSALEFNLSGGDSLNDINNLLGCDDEDDNHEHMLDNILQECAMDDPKALNQATNFWNGILDGEAAVDEVEMADQLLDCIDEKKSKVGAADTSKRAGRNRKARLIQAPVGSSAFTVCPTAETLKERELFFSQAPPVEVPPKEKTPAEVELPEVVVKETANLPVKVEAVEKPQSEVLPVAPQPQQLQPQAITLPTTQLINIPAQISTQKQHQQPQVTQLLNQFANAGPQIIARTEYGGGAAVGDIVTITPHTGSSPLPTLTAQQQLQHQLAQAQLRNVTVQQRQATPQNPNQNQNPQQQLLFQMQRDPSRSLTPLQAAGAGATGNHLIYTTSCGEIVTAGAAASASQKVTYAIQKAGVSSGGATTASIGPNTVITLSNVKVQNDDISSGGSGNSGSSVNIINTASGQQLAVHSIAGMQQQGQQQVQQVTTSTPLLVATPTRNNVQQQQQQLVQQQPIVWRQVSGTNTAVATTAVLSTTVDSSPKAVTNQILWTSRATQKRQLNGPENTDINKLLLNRKLPRKQQIQQQHQQIQLTKQQLQQLVQHEELDDLVATSTGNSGDQMETGDGLQQQQQQQQQQQQLQKLSKVIKMSQFPLLVSDVSLQQQQSVSGQAQQQQLKPNSAAAIAANHNYSLHPASTAIITAQATPQQANKIFLTSSNSGGGGSAGNFTIATASELQAAAAGQKLHYKELPNSNLKLNFVSSAGTGEQTQQVGATTVLLNKSQQQQQQQQHQKLKTLATTGNSQTGQGDKRVLYTSLLNVKPLQKNNSGQMQMQLGPGGLQQVLRGRLNNSAIITRTLPLGTTVNSTGGAVGPTTTTIRQLVTTNANNVSSQDGNLLSAKEVGKALTVEQVIASANNGGVVLPTSNNNNNNNGSGAGGNGGPLNSGVNATGAGGGGSTGAGVGGAGVTSTINRXDADGSGSNSXHRAQPLQVPNGPLLSLASTQTEAETQAVAISMPLADAHVALGQLLQQHHCSCTVCLVNKSELV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43572-1", "uniprot_id": "EPL1_YEAST", "id": "P43572-1", "name": "Enhancer of polycomb-like protein 1", "aln": "MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMG--SGHTKHKDYIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSDILTEDEFEILCSSFEHAIHERQPFLSMD--PESILSFEELKPTLIKSDMADFNLRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQ-RLRALHQELKNAKDLALLVAKREN----------------------------------------------------VSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAAAAAAAAKAKNNKRNNQ----------LEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGKQ-LANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEK-------RKIEDADVFFNLTDDPFNPVFDMSLPKNFSTSNVPFASIASSK--------FQIDRSFYSSHLPEYLKGISDDIRIYDSN--------GRSRNKDNYNLDTKRIKKTELYDPFQEN---------------LEIHSREYPIKFRKRVGRSNIKYVDRMPN--------------------------------------------------------------------------------------------FTTSSTKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDS------PQNEYGIKFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLK----------QKHIQHLQQQQQQQQQQQQQAQQQKQKSQNNNSNSSN-----SLKKLNDSLINSEAKQNSSITQKNSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** * :. : : :: ::: .* . :* * :: :*:**:**.* **:* : . *: * .:: . . *::.. * .:*::*. ** :.. .: . : :** : . :*:. : ::::* : * :.* : : .: . : : .. . : * : . .:: : : . **:.* .: : **.: :: :::.:.: .: : : . . : . ::: .. . ::. . .: .:.: : .:: . . . . . . . : *. . .. :.:.:: : * : * . * . . . :: . . : . . . .: ::: : . . .::.: . : : : . : : : : . : . . : . . :. : . . ", "identical_positions": 40, "similar_positions": 187, "identity": "1.84%" }, { "cls_id": "homologset.agr.FB:FBgn0000588", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8YPE2-1", "uniprot_id": "A0A8J8YPE2_RAT", "id": "A0A8J8YPE2-1", "name": "Polycomb protein EED", "aln": "VAGSHARPPRRLGAICDSGGSGGGGGAGSFAAGSGRACLTAVWRRPRPRRQEPGGRRRNMSEREVSTAP---AGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSK-KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75530-1", "uniprot_id": "EED_HUMAN", "id": "O75530-1", "name": "Polycomb protein EED", "aln": "-----------------------------------------------------------MSEREVSTAP---AGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSK-KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q921E6-1", "uniprot_id": "EED_MOUSE", "id": "Q921E6-1", "name": "Polycomb protein EED", "aln": "-----------------------------------------------------------MSEREVSTAP---AGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSK-KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q566T0-1", "uniprot_id": "EED_DANRE", "id": "Q566T0-1", "name": "Polycomb protein eed", "aln": "-----------------------------------------------------------MKMRRKMSEPHGEAGNEMPN-KKQKLSSDENSNPDLSGDDNDDAVSVESGTHPERPDTPTNTASAPGRKSWGKGKWKSK-KCKYSFKCVNSLKEDHGQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTFDCSSSHPLLAVAGSRGIIRIINHITMQCVKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADFDLLGEKIMSCGMDHSLKLWRLDSERLQRAIRGSYEYNPSKTNRPFVSQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGRMEDDIDRIKPNESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTLPRCTSAIRQTSFSRDSSILIAVCDDASIWRWDRLR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24338-1", "uniprot_id": "ESC_DROME", "id": "Q24338-1", "name": "Polycomb protein esc", "aln": "----------------------------------------------------------------------------MSSDKVKNGNEPEESE-ESCGDE---SASYTTNSTTSRSKSPSSSTRSKRR---GRRSTKSKPKSRAAYKYDTHVKENHGANIFGVAFNTLLGKDEPQVFATAGSNRVTVYECPRQGGMQLLHCYADPDPDEVFYTCAWSYDLKTSSPLLAAAGYRGVIRVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLNTPEFHHKIELSNTFSQEKSTLPFPTVTKHFPDFSTRDIHRNYVDCVQWFGNFVLSKSCENAIVCWKPGQLHQSFEQVKPSDSSCTIIAEFEYDECEIWFVRFGFNPWQKVIALGNQQGKVYVWELDPSDPEGAHMTTLHNSRSVATVRQIAFSRDASVLVYVCDDATVWRWNRRQTTSI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * :: .. *:*: : .**: :.* :.: ..*..:*:.:. : * *: . *** *.: ::* . :**:*. :*** ** :.:* ****.******:*** ** ::**:.*.*.*.** ******::* .:* ****.** **:**:*: :.: :*:***:*********:. :**** *****:******:.. :**:************ *::: *::*:*.********* ::: .: . *. * :. .*:. ** : . ******************:*:*:::***************::.:.::::**.:*. **:..*:*.:*:**::**.:: ***::***** **:***:*: .**. *: *** :. :::** :****:*:*: *****::***:* : ", "identical_positions": 210, "similar_positions": 142, "identity": "41.34%" }, { "cls_id": "homologset.agr.FB:FBgn0000591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "-----------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASV------CSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSG-----------GPPSLTPASASAPAP-SPPVP----PPSSLG----------------------------------------LWRPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "-----------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATL------YSSAAPGPLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSD-----------DSPSLTLPPAPAPAP-SPPVP----PPGSSG----------------------------------------LWRPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y543-1", "uniprot_id": "HES2_HUMAN", "id": "Q9Y543-1", "name": "Transcription factor HES-2", "aln": "-----------------MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPASS------WPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGPG----------------------------------------LWRPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ70-1", "uniprot_id": "A0AB32TZ70_DANRE", "id": "A0AB32TZ70-1", "name": "", "aln": "MTPNIITEAHPHSFGSRMTVAQRK-EAHELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTVRFLRDLPS----------SSAKGQTDSYKEGYKACLQRISTMLPQS-NLETEAHQRVSEFIHTCSS--------------RWRLLHRPARTAVLRTQK---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NTZ6-1", "uniprot_id": "A0A8M1NTZ6_DANRE", "id": "A0A8M1NTZ6-1", "name": "", "aln": "--------MDMTATKLQQNSCQLHISSKEERKLRKPLIERKRRERINLCLDQLRETVVAVFKPDQ---SKLEKADILEMTVKHLQNIQSSR----VSDPVLNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLLNHLFKSLP---------LSAKDCPRLPKTSLTSVPSDHSEYSSFHVDETASPKPCSSSPFLCKRPNQSQNQHFTPIRMPHDVESSHLSV-LQMWRPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "----------MTASNMG-NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQ---SKLEKADVLEITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSP-PSSPTHSLVRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13098-1", "uniprot_id": "ESM8_DROME", "id": "P13098-1", "name": "Enhancer of split m8 protein", "aln": "--------------------MEYTTKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDG--ILRMDKAEMLESAVIFMRQQKTPK----KVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFIQNSMDCSSMDKAPLSPASSGYHSDCDSPAPSPQP-------------------------------MQQPLWRPW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :* **::*::** *:* .*.:*: : : :::**::** :* .:.: : : ** .: .: :: :. : .: . ", "identical_positions": 17, "similar_positions": 39, "identity": "7.2%" }, { "cls_id": "homologset.agr.FB:FBgn0000592", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NT32-1", "uniprot_id": "EST5A_HUMAN", "id": "Q6NT32-1", "name": "Carboxylesterase 5A", "aln": "----------MSGNWVHPG-QILIWAIWVLAAPTKGPSA--EGPQRNTRLGWIQGK-QVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQP-ASPWDNLREATSYPNLCLQNSEWL-LLDQHMLKVHYPKFGVSEDCLYLNIYAP-AHADTGSKLPVLVWFPGGAFKTGSAS--------IFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNN-ASDSEALLRCLRTKPSKELLTLSQKTK-----------SFTRVVDG-----AFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS----GSNKSLALHLIQNILHIP-------PQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAG-APVYFYEFRHRPQ-----CFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGND----LSLWPAYNLTEQYLQLDLNMSLG---QRLKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5GRG2-1", "uniprot_id": "EST5A_RAT", "id": "Q5GRG2-1", "name": "Carboxylesterase 5A", "aln": "----------MSGDWVHTG-QALIWVLWIFAAIIRGSVT--EEPHRYTRLGWVQGK-QATVLGRLEPVNVFLGIPFAAPPLGPLRFSNPQP-PIPWHDLREATTYPNVCFQNLEWL-FIYQNLLKVHYPKLGVSEDCLYLNIYAP-AYANDGSRLPVMMWIPGGGFETGSAS--------IFDGSALAAYEDVLIVTIQYRLGIFGFFNTQNQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCN-VSDSKVLLKCLREKSSLELLSLGQKTK-----------AFTRVVDG-----SFFPEEPMELLSQKTFKTVPSIIGVNNQECGYILPMREAPEILF----GSNESTALTLIHVLLHIP-------PQYMHIVAKDYFHGKHSLTDIRDTLLDLFGDVFFVVPGLVTARNHRDAD-GPVYFYEFQHRPN-----CFQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDD----LPLWPAYDQNESYLKLDVNISTG---WRLKDRRVEFWTDTLPLIMSASKALLSPTFPLILFSLLPPSLLSIAS---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3R0-1", "uniprot_id": "EST2A_RAT", "id": "Q8K3R0-1", "name": "Pyrethroid hydrolase Ces2a", "aln": "----------MPLARLPGWLYVVACGLLLLLQHVHGQDS--ASPIRNTHTGQVRGS-FVHVKDTKSGIHTFLGIPFAKPPVGPLRFAPPED-PEPWSGVRDATSQPAMCLQ-TDIMNLDGIKEMKLTVHPTPMSEDCLYLNIYTP-AHAREGSNLPVMVWIHGGGLVLGSAS--------MNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQNARGNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHVVSPMSKGLFHGAIMQSGVALLPDLISDKSEVVY--KTVANLSGCE-APDSEALIRCLRAKSKQEILAINQVFK-----------MIPGVVDG-----KFLPKHPQELLASGDFHPVPSIIGINTDECGWGIPVFLGLDHIIKKITRETLPTVLKSTAAQMMLP-------PECIDLIMEEYMGDTENPETLQEQFRHMLGDFMFVIPALQVAHFQRSQ--APVYFYEFQHLPS-----FIKQVRPSHVKADHGDDILFVFGSYLWG----MTFDLTEEEELLKRRVMKYWANFARTGNPNGED----LPHWPVLDHDEQYLQLNTQPAVG---RALKARRLQFWTKTLPQKIQELKGSQSKHAEL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70631-1", "uniprot_id": "EST2C_RAT", "id": "O70631-1", "name": "Acylcarnitine hydrolase", "aln": "----------MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGK-LDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPED-PEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTP-AHAHEGSNLPVMVCIHGGALVIGMAS--------MCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVS--TTVAKLSGCE-ATDSETLVRCLRAKSGAEILVINKVFK-----------MIPAVVDG-----EFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLP-------PECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSH--APVYFYEFQHAPS-----YFKNVRPPHVKADHADEVPFVFGSFFWG----IKVDFTEEEKLLSRRMMKYWANFARHGNPNSEG----LPYWPVLDHDEQYLQLDTQPAVD---RALKARRLQFWTKTLPQKIQELNGAQKNHAEL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3V7J5-1", "uniprot_id": "EST2E_RAT", "id": "G3V7J5-1", "name": "Pyrethroid hydrolase Ces2e", "aln": "MAQTRAWKSIMPLESLPGWLNAVVWGLLLLFCQVQGQDS--ASPIRNTHTGQVRGS-FVHVKDTKSGVHTFLGIPFAKPPIGPLRFAPPEP-PEPWSGVRDGTSHPAMCLQNIDGLNLENLK-IKMSRSPVSMSEDCLYLSIYTP-AHTHKDSNLPVMVWIHGGGLCWGMAS--------TYDGSMLAAIEDVVVVTIQYRLGILGFFSTGDEHARGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIY--TMVANLSGCE-PVDSEALMSCLREKSEEEMLAINNIVR-----------TISGVVDG-----KFLPRHPLELLASVDFHPVPSIIGINSDEYGWIIPMLH-PDSTMKEINRETMRAVLKNTAVQMMLP-------PECSDLLMEEYMGDTEDSKTLQIQFNEMMGDFIFVIPALQVAHFQRSH--APVYFYEFQHQSN-----FLKDIRPPHVKADHGDELPYVIGYLFWD----MKFVFTEEEKLLSRKMIKYWANFARHGNPNSEG----LPYWPALDHDEQYLQLDIQPVVG---RALKARRLKFWTKTLPQKIQELKGSQDNHTEL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64285-1", "uniprot_id": "CEL_MOUSE", "id": "Q64285-1", "name": "Bile salt-activated lipase", "aln": "----------------MGRLEVLFLGLTCCLAAACAAKLG----AVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKT----LENPQR-HPGWQGTLKATNFKKRCLQ------------ATITQDNTYGQEDCLYLNIWVPQGRKQVSHNLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGMALSPWAIQKNP--LFWAKTIAKKVGCP-TEDTGKMAACLKITDPRALTLAYKLPVKKQEYPVVHYLAFIPVIDG-----DFIPDDPINLYNNTADIDYIAGINNMDGHLFATIDVPAVDKTKQTVTEEDFYRLVSGHTVAKGLKG-------AQATFDIYTESWAQDPSQENMKKTVVAFETDVLFLIPTEIALAQHKAHA-KSAKTYSYLFSHP-----SRMPIYPKWMGADHADDLQYVFGKPFAT-----PLGYRPQDRAVSKAMIAYWTNFARSGDPNMGNSPVPTHWYPYTLENGNYLDITKTITSASMKEHLREKFLKFWAVTFEVLPTVTGDQDTLTPPEDDSEVAPDPPSDDSQVVPVPPTDDSVEAQMPATIGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08171-1", "uniprot_id": "EST6_DROME", "id": "P08171-1", "name": "Esterase-6", "aln": "------------MNYVGLGLIIVLSCLWLGSNASDTDDP----LLVQLPQGKLRGR-------DNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ---------WDQFTPGANKLVGEEDCLTVSVYKP--KNSKRNSFPVVAHIHGGAFMFGAAW--------QNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRA--FELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVP---FAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFENFVRD------VEMRPDEQIISRNFINMLADFASSDNG-----------------SLKYGECDFKDNVG--------------SEKFQLLAIYIDGCQNRQHVEFP----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :.* : .:*:* . : *: * . ..*. *:* . .**** :.:: * :**: : **.: * . . . : ..::* ..**:* :**..* : . **:. ** *: *::.** ***: : :.* ***. *: : * : *: ** *: * :. *: : **: . : . : *:: ::. .* :: . :. . : : : : : *.:* . :: .. * : . : * *: :: . ::. :.: .: : ** .: .* . : .: ", "identical_positions": 61, "similar_positions": 115, "identity": "9.21%" }, { "cls_id": "homologset.agr.FB:FBgn0000594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68G49-1", "uniprot_id": "Q68G49_RAT", "id": "Q68G49-1", "name": "Carboxylic ester hydrolase", "aln": "--------------------------------------------MRLYPLVWLFLAACTAWG-YPSSPPVVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKSPLGSLRFAPPQP-AESWNFVKNTTSYPPIYSLSTSRCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVGGS--STYDGQALSAHENVVVVTIQYRLGIWGFFST-GDEHSQGNWGHLDQLAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLNTALITT--DSKPIANLIATLSGCKTTTS----AVMVHCLRQKTEDELLETSLKLNLFKLDLFGNPKESYPFLPTVIDGVVLSKTPEEILAEKSFNTVPYIVGINKQEFGWIIPM-LMGYPLS---------EGKLDQKTANSLLWKSYPTLKISEKMIPMASEKYLG---GTDDPAERKDLFKDLVADVIFGVPSVMVSRSHRDAG-APTFMYEFEYRPSF-----VSAMRPKTVIGDHGDEIFSVFGSPFL-KDGASEEETNLSKMVMKYWANFARNGNPN---GGGLPHWPEYDQ-KEGYLKIGASTQAAQR-LKDKEVAFWSELKAKEAAEEPSHWKHVEL-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCC2-1", "uniprot_id": "EST1_MOUSE", "id": "Q8VCC2-1", "name": "Liver carboxylesterase 1", "aln": "--------------------------------------------MWLCALSLISLTACLSLG-HPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEP-AEPWSFVKHTTSYPPL-------CYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLVIDGA--STYDGVPLAVHENVVVVVIQYRLGIWGFFST-EDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGR--AARPLAKKIAALAGCKTTTS----AAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPM-FLDFPLS---------ERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLG---GTEDPATMTDLFLDLIGDIMFGVPSVIVSRSHRDAG-APTYMYEYQYRPSF-----VSDDRPQELLGDHADELFSVWGAPFL-KEGASEEEINLSKMVMKFWANFARNGNPN---GEGLPHWPEYDQ-KEGYLQIGVPAQAAHR-LKDKEVDFWTELRAKETAERSSHREHVEL-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23141-1", "uniprot_id": "EST1_HUMAN", "id": "P23141-1", "name": "Liver carboxylesterase 1", "aln": "--------------------------------------------MWLRAFILATLSASAAWG-HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQP-AEPWSFVKNATSYPPM-------CTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG-DVKPLAEQIAITAGCKTTTS----AVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS---------EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLG---GTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAG-APTYMYEFQYRPSF-----SSDMKPKTVIGDHGDELFSVFGAPFL-KEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYNQ-KEGYLQIGANTQAAQK-LKDKEVAFWTNLFAKKAVEKPPQTEHIEL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4AA05-1", "uniprot_id": "D4AA05_RAT", "id": "D4AA05-1", "name": "Carboxylic ester hydrolase", "aln": "MIRPLDCTWMGVVTRPHNVRRVMQSPSEEHRDPVTGPQSNWPSTMWLFALALTSLNTYMAFG-HPSSPPVVDTLQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQP-AESWSFVKNATSYPPM-------CSQITGVGPVLSEVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGA--STFDGLALSTHEKVVVVVIQYRLGIWGFLST-GDEHSRGNWGHFDQVAALQWVQNNIVNFGGDPNSVTLFGESAGGESVSVLVLSPLTKNLFHRAISESGVALTPCLFRE--NTRLAAEQVAIATGCAATTS----ADIVRCLREKTEEELLATTLKMKFFALDLHGDPRESYPFLTTVIDGVLLPKAPEEILSEKNFNTVPYIVGINKQEFGWFIPT-MMGYPLS---------ESKLDQKTATSLLWKSYPLTNISKELTPVATEKYLG---GSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHRDAR-ATTYVYEFKYHPSF-----VSDMRPKTVIADHGDEVYSVWGTPFL-KEGASEEEINLSTMMMKFWGNFARNGNPN---GEGLPHWPEYDE-KESYLQIGTTIQQAQK-LKYKEVAFWTGLRGMEVEEATEEDTQK---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23953-1", "uniprot_id": "EST1C_MOUSE", "id": "P23953-1", "name": "Carboxylesterase 1C", "aln": "--------------------------------------------MWLHALVWASLAVCPILG-HSLLPPVVDTTQGKVLGKYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQP-AEPWSFVKNATSYPPM-------CSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGA--SPYNGLALSAHENVVVVTIQYRLGIWGLFST-GDEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKK--NIQAVNEIIATLSQCNDTSS----AAMVQCLRQKTESELLEISGKLVQYNISLS-----------TMIDGVVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWIIPM-MLQNLLP---------EGKMNEETASLLLRRFHSELNISESMIPAVIEQYLR---GVDDPAKKSELILDMFGDIFFGIPAVLLSRSLRDAG-VSTYMYEFRYRPSF-----VSDKRPQTVEGDHGDEIFFVFGAPLL-KEGASEEETNLSKMVMKFWANFARNGNPN---GEGLPHWPEYDE-QEGYLQIGATTQQAQR-LKAEEVAFWTELLAKNPPE-TDPTEHTEHK------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AE76-1", "uniprot_id": "D4AE76_RAT", "id": "D4AE76-1", "name": "Carboxylic ester hydrolase", "aln": "-----------------------------------MAEAGWSMKWTLDLSLTLWLVVQTALGALHTKEPLLITKHGILQGKQVHVG--DTPIRVFLGVPFSQPPVGTRRFAPPEP-PLPWNGIRDATTYPPS-------CLQES-WGQITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSA--STYEGSELAARGKVVLVFLQYRLGILGFFST-GNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITH--DPLKSAKKIAHLAGCDHNST----KIMVKCLKALPAEKVMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVFPEDPVVLLTRGQVKPVPYLLGVNSAEFEWSLPF-LMKLQLN---------QRIMNKNYITKLLWSCSILLNITEEQIPLVAREYLSDAISHHDWKMFRNHLIDLVGDATFVYATLQAARYHRDAG-SPVYLYEFKHHAPG-----IIVK-PRSDGADHGDELSYLFGSPFS-KGSSRGEEKEFSLQMMKYWANFAHTGDPN---DRELPYWPRFDK-EEKYLQLDFDTRVGVK-LREKQMTFWRRLRQPQKP------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22303-1", "uniprot_id": "ACES_HUMAN", "id": "P22303-1", "name": "Acetylcholinesterase", "aln": "------------------------------MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEP-KQPWSGVVDATTFQSV---------CYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSP-TPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFR-------FSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVY--GAPGFS---------KDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQG-ARVYAYVFEHRAS-------TLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18167-1", "uniprot_id": "ESTP_DROME", "id": "P18167-1", "name": "Esterase P", "aln": "--------------------------------------------MSIFKRLLCLTLLWIAALESEADPLIVEITNGKIRGK------DNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVE--------------CMQWNQFINENNKLMG---DEDCLTVSIYKPK-KPNRSSFPVVVLLHGGAFMFGSG--SIYGHDSIMREGTLLVVKISFGLGPLGFAST-GDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQ--GGRRRAFELGRIVGCGHTNVS---AELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFG--PVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLA---DRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAY-RTGIRPDEEVISKKFIGMLEDFALN-------DKGTLTFGECNFQNNVNSKEYQVLRISRNACKNEEYARFP--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * : * : .:* :: * *. ** .*:* *. : .:* . .**** :.:: * . **:* . **.: ... . : : ::* :.: :* *: : . . ** . ** **:*::.*: *** * .:.::*.*:*. *. :: : * : *: *. :. * : **: . . :: . . . .: . * : .. : : . : : : . . : .. : . :. * . . .: : : . *. :. ::. . . :* :: .: :** . . : : . . : : : ", "identical_positions": 52, "similar_positions": 126, "identity": "7.61%" }, { "cls_id": "homologset.agr.FB:FBgn0000606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQ30-1", "uniprot_id": "F1LQ30_RAT", "id": "F1LQ30-1", "name": "Homeobox even-skipped homolog protein 1", "aln": "-MESRKDMVMFLDGGQLGSLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCAT---GNAEYQHSKA-----PDSDALGSSPNSGSEAPKSNGGSGG-SGSQGTLACSAS----DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAG-GLPYPFPSHLPLPYYSPVGLGAASAASAAA-------SPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLG---------------------ASAG-------GPCSCLACHSGPSNGLAPR---AAAAS------------------------DFTCASTS-RSDS-FLTFAPSVLSKASSVA-LDQREEVPLTR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23683-1", "uniprot_id": "EVX1_MOUSE", "id": "P23683-1", "name": "Homeobox even-skipped homolog protein 1", "aln": "-MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCAT---GNAEYQHSKA-----PGSDALGSSPTSGSEAPKSNGGSGG-SGSQGTLACSAS----DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAG-GLPYPFPSHLPLPYYSPVGLGAASAASAAA-------SPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLG---------------------ASAAA--AAAAGPCSCLACHSGPANGLAPRAAAAAAAS------------------------DFTCASTS-RSDS-FLTFAPSVLSKASSVAALDQREEVPLTR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49640-1", "uniprot_id": "EVX1_HUMAN", "id": "P49640-1", "name": "Homeobox even-skipped homolog protein 1", "aln": "-MESRKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCAT---GNAEYQHSKG-----SGSEALVGSPNGGSETPKSNGGSGG-GGSQGTLACSAS----DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAG-GLPYPFPSHLPLPYYSPVGLGAASAASAAA-------SPFSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLG---------------------ASAG-------GPCSCLACHSGPANGLAPR---AAAAS------------------------DFTCASTS-RSDS-FLTFAPSVLSKASSVA-LDQREEVPLTR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4ACC8-1", "uniprot_id": "D4ACC8_RAT", "id": "D4ACC8-1", "name": "Homeobox even-skipped homolog protein 2", "aln": "MMERIRKEMILMERGLHSPTAGKRFSNLSDSSGSAVLEALENSQHPARLSPR--LPSAPLHGALG--DLPAKGKFEIDTLFNLQHPSSESTVS--SEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAQLKENNAKGYAESGSVAGTTTSATGSGLGSLHGGGGG-NSGGAALGGSGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATG-SLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPATAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGSGGGGGGG----AGTAGGSDFGCSAAAPRSESGFLPYSAAVLSKT-AVSPPDQRDEAPLTR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49749-1", "uniprot_id": "EVX2_MOUSE", "id": "P49749-1", "name": "Homeobox even-skipped homolog protein 2", "aln": "MMERIRKEMILMERGLHSPTAGKRFSSLSDSAGGAVLEALENSQHPARLSPR--LPSAPLHGALG--DLPAKGKFEIDTLFNLQHPSSESTVS--SEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAPLKENNAKGYTESGSVAGTTTSASGSGLGSLHGGGGGGNSGAAALGGSGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATG-SLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGSSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGSGGGGGGG----AGTAGGSDFGCSAAAPRSESGFLPYSAAVLSKT-AVSPPDQRDEAPLTR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03828-1", "uniprot_id": "EVX2_HUMAN", "id": "Q03828-1", "name": "Homeobox even-skipped homolog protein 2", "aln": "MMERIRKEMILMERGLHSPTAGKRFSNLSNSAGNAVLEALENSQHPARLSPR--LPSAPLHSALG--ELPAKGKFEIDTLFNLQHTGSESTVS--SEISSAAESRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLHGGSGG-SGGSAALGGSGS--GADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATG-SLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFLPYSAAVLSKT-AVSPPDQRDEAPLTR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06602-1", "uniprot_id": "EVE_DROME", "id": "P06602-1", "name": "Segmentation protein even-skipped", "aln": "-------------------MHGYRTYNMESHHAHHDAS-------------------------------PVDQKPLVVDLLATQYGKPQ------TPPPSPNECLSSPDN-----------------------------------------------------------SLNGSRGS------EIPADPS------VRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAG-PHMHHPHMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPAPLTTTSPLPAPGLLMPSAKRPASDMSPPPTTTVIAEPKPKLFKPYKTEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .:.. . . *.. : . .. :. . .: . :*. *. : . * :*********:*:.*******:************** *****:*****************:*::**:.* : :: : *:. .: *: .: * . .. *.:: . : * .:: . .:* . : : * .*. * .:*. ..* . .. :: .. : : .: . : . ... * . : .: . * * ", "identical_positions": 77, "similar_positions": 91, "identity": "15.28%" }, { "cls_id": "homologset.agr.FB:FBgn0000611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGR6-1", "uniprot_id": "A0A8I6AGR6_RAT", "id": "A0A8I6AGR6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDD----QSRMLQTLAGVNLAGHSVQGGM--------ALPPPPHGHEGAD--GDG-RKQDIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAAS-GGS-----SDNSIEHSDYRAKLTQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS--------------------------GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGANSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35317-1", "uniprot_id": "PBX3_MOUSE", "id": "O35317-1", "name": "Pre-B-cell leukemia transcription factor 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDD----QSRMLQTLAGVNLAGHSVQGGM--------ALPPPPHGHEGAD--GDG-RKQDIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAAS-GGS-----SDNSIEHSDYRAKLTQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS--------------------------GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGANSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40426-1", "uniprot_id": "PBX3_HUMAN", "id": "P40426-1", "name": "Pre-B-cell leukemia transcription factor 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDD----QSRMLQTLAGVNLAGHSVQGGM--------ALPPPPHGHEGAD--GDG-RKQDIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAAS-GGS-----SDNSIEHSDYRAKLTQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS--------------------------GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B506-1", "uniprot_id": "A0A8M3B506_DANRE", "id": "A0A8M3B506-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDE----QARIMQTLGGVSLAGHSVQGGM--------ALPPP-HGHDGTD--GDG-RKQDIGDILHQIMTITDQSLDEAQAKKHGLNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAAA-GSP-----TDNSIEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQGVGTTITVAQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAAAAAVQNSQTNSPTTPNSGFQMKDEEFQLDSAENKNTLLTNMFTGSSGSFNLPNSGDLFMSMQNLNGDSYQGAQVGANVQSQVDTLRHVISQTAGYNDVLGGNPMYSPHGLNGNGGWQDATTPSSVISPTEGPGSVHSDTSN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40424-1", "uniprot_id": "PBX1_HUMAN", "id": "P40424-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDE----QPRLMHSHAGVGMAGHPGLS------------QHLQDGAGGTE--GEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAAS-GGAG----SDNSVEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATN---VSAHGSQANSPSTPNS-------------------------AGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZR45-1", "uniprot_id": "A0A8I5ZR45_RAT", "id": "A0A8I5ZR45-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDE----QPRLMHSHAGVGMAGHPGLS------------QHLQDGAGGTE--GEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAAS-GGAG----SDNSVEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATN---VSAHGSQANSPSTPNS-------------------------AGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41778-1", "uniprot_id": "PBX1_MOUSE", "id": "P41778-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDE----QPRLMHSHAGVGMAGHPGLS------------QHLQDGAGGTE--GEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAAS-GGAG----SDNSVEHSDYRAKLSQIRQIYHTELEKYEQ----ACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATN---VSAHGSQANSPSTPNS-------------------------AGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9QFI5-1", "uniprot_id": "A0A8M9QFI5_DANRE", "id": "A0A8M9QFI5-1", "name": "Pre-B-cell leukemia transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDE----QPRLMHAHAAVGMSGHPGLA------------PHIPDNTGAAD--GDG-RKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPPDAQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAAS-GGVG----ADNSAEHSDYRAKLSQIRQIYHTELEKYEQVSKHACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANMYAARTAVNAAS---VSAHGSQANSPSTPNS-------------------------AGSAGSFNMSNSGDLFMSVQSLNGDSYQGSQVGANVQSQVDTLRHVISQTGGYSDGLAANQMYSPQGINANGGWQDPTTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABZ3NN70-1", "uniprot_id": "A0ABZ3NN70_RAT", "id": "A0ABZ3NN70-1", "name": "", "aln": "MNRVVGEHSRGRTPHRQARNPGGRATLHPTAGSAGPGANPASPRPPRRSPPPPAAARPASPRPRLLPVPPLLPSSSSRSPPPAASLAPPSPSSLLSHTHPRLGLLSLSLRLHFLRRRGPGSPVGVPRRHPGSPLQCRGEPPKGAGRRVAGRGWGGGSSGPSEFGGEVTRRGEGRAGRGPQGPPPAMDERLLGPPPPGGGRGGLGLVGGEPGGPG--------EPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVS----PDNSIEHSDYRSKLAQIRHIYHSELEKYEQ----ACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVAQG-----GHSRTSSPTPPSS-------------------------AGSGGSFNLSGSGDMFLGMPGLNGDSYP--------ASQVESLRHSMGP-ASYGDNIGGGQIYSPREMRANGGWQEAVTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35984-1", "uniprot_id": "PBX2_MOUSE", "id": "O35984-1", "name": "Pre-B-cell leukemia transcription factor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDERLLGPPPPGGGRGGLGLVGAEPGGPG--------EPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVS----PDNSIEHSDYRSKLAQIRHIYHSELEKYEQ----ACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVAQG-----GHSRTSSPTPPSS-------------------------AGSGGSFNLSGSGDMFLGMPGLNGDSYP--------ASQVESLRHSMGP-GSYGDNIGGGQIYSPREIRANGGWQEAVTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40425-1", "uniprot_id": "PBX2_HUMAN", "id": "P40425-1", "name": "Pre-B-cell leukemia transcription factor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDERLLGPPPPGGGRGGLGLVSGEPGGPG--------EPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVS----PDNSIEHSDYRSKLAQIRHIYHSELEKYEQ----ACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQG-----GHSRTSSPTPPSS-------------------------AGSGGSFNLSGSGDMFLGMPGLNGDSYS--------ASQVESLRHSMGP-GGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40427-1", "uniprot_id": "EXD_DROME", "id": "P40427-1", "name": "Homeobox protein extradenticle", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MED----PNRMLAHTG--GMMAPQGYG------------LSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQ----ACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQ----------VSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASP-------YSMAGPPS------------------------------GTTTPMMSPAPPQDSMGYP-MGSGGYD--------------------QQQPYDNSMGG---YDPN--------------------------LHQDLSP-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6YV86-1", "uniprot_id": "A0A8M6YV86_DANRE", "id": "A0A8M6YV86-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQPQQPITGNGPSASRGGGLSVHPGMHPLNSIHPAAQHRPDGADPAGLEGTENGHDNRRDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSMRNVQEEEPPDPQLVRLDNMLLAEGVAGPEKGGGAAAAVSAATSS-GGMS----PDSSLEHSDYKSKLSQIRNIYHTELEKYEQ----ACSEFTTHVMNLLREQSRTRPVSPREIERMVAIIHRKFSSIQTQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKQCSITVSQ----------VSNWFGNKRIRYKKNIGKYQEEANLYAMKTALGATQ---------SEDSPHTPNS--------------------------TGSGSFSLSGSADCFLGVPPMNGEQPP------------------YHMGAQDAQSRFSERLYITRESRTNGNWQEQNSPPSAASP----GTDHSVDSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4AA41-1", "uniprot_id": "D4AA41_RAT", "id": "D4AA41-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAP---------------LRPVPPQPAPRRSPPTAPLGHDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKSALFSVLSEIKGKTAVSVQ-TQEEDPPDAQLLRLDNMLLAEGVSRPEKRGRGGAAAGS-TATPGGCP----NDNSIEHSDYRAKLSQIRQIYHSELEKYEQ----ACREFTTHVTNLLREQSRVRPVSSGEIEHMVSTIHSKFSAIQRQLKQSTCEAVMTLRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEETKEELARKGGITVSQ----------VSNWFGNKRIRYKKNTGKFQEEATMYTGKTST-VTKTR---VSGGQTSCQSTPSP--------------------------DSCGPFPLTSGSDMVLTLRTLAFLQPP--------------------PGGVCLQPLAHG------------SWQRATTSQPSSSPAGDSGSFNSDASD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NE9-1", "uniprot_id": "PBX4_MOUSE", "id": "Q99NE9-1", "name": "Pre-B-cell leukemia transcription factor 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAP---------------LRPVPPQPAPRRLPTTAPLGHDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKSALFSVLCEIKGKTAVSIQ-FQEEDPPDAQLLRLDNMLLAEGVSRPEKRGRG-AAAGS-TATPGGCP----NDNSIEHSDYRAKLSQIRQIYHSELEKYEQ----ACREFTTHVTNLLREQSRVRPVSCREMEHMVNTIQSKFSAIQRQLKQSTCEAVMTLRSRFLDARRKRRNFSKQATDVLNEYFYSHLSNPYPSEETKEELARKGGITVSQ----------VSNWFGNKRIRYKKNTGKFQEEATMYTGKAST-VTKAR---RPRGQSSCQSTPSP--------------------------GPCGPLPLTNGSDVVLTLRTLAFLQPP--------------------TGGVCLQPLVHS------------NWQRAAP-QPASSPAGESGSFNWDAASN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYU1-1", "uniprot_id": "PBX4_HUMAN", "id": "Q9BYU1-1", "name": "Pre-B-cell leukemia transcription factor 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAP---------------PRPAPSPPAPRR--------LDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCP----NDNSIEHSDYRAKLSQIRQIYHSELEKYEQ----ACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQ----------VSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVG---VPGNHASCLSTPSS--------------------------GSSGPFPLPSAGDAFLTLRTLASLQPP--------------------PGGGCLQSQAQG------------SWQGATPQPATASPAGDPGSINSSTSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CY08-1", "uniprot_id": "MTAL2_YEAST", "id": "P0CY08-1", "name": "Mating-type protein ALPHA2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKIPIKD-LLNPQITDEFKSSILDINKKLFSICCNLPKLP--------------------ESVTTEEEVELRDILG------------------------------FLSRANKNRKISDEEKKLLQT-----TSQLTTTITVLLKEMR------SIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHR----FTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQ----------IKNWVSN-RRRKEKTITIAPELADLLSGEPLAKKKE------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CY09-1", "uniprot_id": "HMAL2_YEAST", "id": "P0CY09-1", "name": "Silenced mating-type protein ALPHA2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKIPIKD-LLNPQITDEFKSSILDINKKLFSICCNLPKLP--------------------ESVTTEEEVELRDILG------------------------------FLSRANKNRKISDEEKKLLQT-----TSQLTTTITVLLKEMR------SIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHR----FTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQ----------IKNWVSN-RRRKEKTITIAPELADLLSGEPLAKKKE------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*.: *: : :. . :: **.: .:: . :.: * * : * : :: : *:* . * : : ::** : **:* * :: : * .: : : : . : :: :: .:* *.*: :*:.:* .::.*** . : *:* :: .:: * :.**..* * * :*. * * : : . ", "identical_positions": 36, "similar_positions": 77, "identity": "5.29%" }, { "cls_id": "homologset.agr.FB:FBgn0000617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKE0-1", "uniprot_id": "TAF9_RAT", "id": "Q5BKE0-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------MASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KAPTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQAMSVSTKVGTPMSLTGQRFTVQMPASQS---PAVKASIPATPAVQNVLINPSLIGSKNILITTNMVS-QNTANESANALKRKREEEDDDDDDDDDD-YDNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI33-1", "uniprot_id": "TAF9_MOUSE", "id": "Q8VI33-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------MASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKAT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KAPAPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQS---PAVKASIPATSTVQNVLINPSLIGSKNILITTNMVS-QNTA-ESANALKRKREDDDDDDDDDDDDDYDNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16594-1", "uniprot_id": "TAF9_HUMAN", "id": "Q16594-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MESGK------TASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKAT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQK----KASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPTSQS---PAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANESSNALKRKRE--DDDDDDDDDDDYDNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZA9-1", "uniprot_id": "TAF9B_MOUSE", "id": "Q6NZA9-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MEPAK------MAPIKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVK----KGPN-QGRL-VPRLS--AVSSRPTTPPVAP--PQAVSGPNKAATPVSVTSQRFAVQIPPSQS---TPAKP-APAATAVQNVLINPSMIGPKNILITTSMVSSQNTATDS-NPLKRKHD--DDDD-------NDTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62880-1", "uniprot_id": "TAF9B_RAT", "id": "Q62880-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MEPSK------MAPLKNAPRDALVMAQILKDMGITDYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVK----KGPN-QGRL-VPRLSVGAVSSRPTTPTVAP--PQAVSVPNKVATPVSVTSQRFAVQIPTSQS---TPAKP-APAATSVQNVLINPSMIGSKNILITTNMVSSQSTATDS-NPLKRKHD--DDDDDDDDDDDNDTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBM6-1", "uniprot_id": "TAF9B_HUMAN", "id": "Q9HBM6-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MESGK------MAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPN-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIK----KGPN-QGRL-VPRLSVGAVSSKPTTPTIAT--PQTVSVPNKVATPMSVTSQRFTVQIPPSQS---TPVKP-VPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEA-NPLKRKHE--DDDD-------NDIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27272-1", "uniprot_id": "TAF9_DROME", "id": "Q27272-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKT-----IDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEEFEFVTN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05027-1", "uniprot_id": "TAF9_YEAST", "id": "Q05027-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF9", "aln": "MNGGGKNVLNKNSVGSVSEVGPDSTQEETPRDVRLLHLLLASQSIHQYEDQVPLQLMDFAHRYTQGVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQYQFKPTAPKELMLQLAAERNKKALPQVMGTWGVRLPPEKYCLTAKEWDLEDPKSM------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : *:*. :: :* . .: :** :* *:::*:.**. :*.** :* .:* . . :. :*:*** : .*. . :..: .:* :*. .** : * ****::****. :: *. . ", "identical_positions": 34, "similar_positions": 52, "identity": "11.53%" }, { "cls_id": "homologset.agr.FB:FBgn0000618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NPA8-1", "uniprot_id": "ENY2_HUMAN", "id": "Q9NPA8-1", "name": "Transcription and mRNA export factor ENY2", "aln": "MVVSKMNKDAQMRAAINQKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JIX0-1", "uniprot_id": "ENY2_MOUSE", "id": "Q9JIX0-1", "name": "Transcription and mRNA export factor ENY2", "aln": "MVVSKMNKDAQMRAAINQKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWF5-1", "uniprot_id": "D3ZWF5_RAT", "id": "D3ZWF5-1", "name": "Transcription and mRNA export factor ENY2", "aln": "-MVSKMNKDAQMRAAINQKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DH42-1", "uniprot_id": "ENY2_DANRE", "id": "Q6DH42-1", "name": "Transcription and mRNA export factor ENY2", "aln": "-----MSKESQMRAAINQKLIEMGERERLKELLRAKLIECGWRDQLKALCKEVIKEKGIEN-VTVEDLVAGVTPKGRALVPDSVKKELLQRIRAFLAQHST---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYX1-1", "uniprot_id": "ENY2_DROME", "id": "Q9VYX1-1", "name": "Enhancer of yellow 2 transcription factor", "aln": "-----MSTSG----AVDQYTVLTGDRSKIKDLLCSRLTECGWRDEVRLMCRNILMEKGTNNSFTVEQLIAEVTPKARTLVPDAVKKELLMKIRTILTEIEEEPDEPEDES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6WNK7-1", "uniprot_id": "SUS1_YEAST", "id": "Q6WNK7-1", "name": "SAGA complex subunit SUS1", "aln": "----MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTN---FTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDTQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::* : *: . :.: * ::* : ** *::: :. : : : . :::: : **. :*.*:.:: :* :** :* : ", "identical_positions": 15, "similar_positions": 37, "identity": "13.64%" }, { "cls_id": "homologset.agr.FB:FBgn0000625", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M478-1", "uniprot_id": "F1M478_RAT", "id": "F1M478-1", "name": "Intestine-specific homeobox", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGPTIQRDIEK-SSGYCEAPEKLGLSFSIEAILKRPTERRNLPRPQSIGGGDSRQTTTSGSKLEKPTQDQPQEERKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEK----------SGSLSAPQQPGEVSLALPSNMDMLGPVLTPTALPTLVP---------------PTECYLLSQTQLASSWFPAQIPLVPWHPWDLQPLPGPLTQQP----------------------------------------------CVPTF-ILPPPNPKWGSICAMPT----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1A546-1", "uniprot_id": "ISX_MOUSE", "id": "A1A546-1", "name": "Intestine-specific homeobox", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGPTIHRDMEK-SSGYCEAPENLGLSFSIEAILKKPTERRSLPRPQSICKEDSRQTTIPGSKLERPPQDQPQEEKKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEK----------SGNLSAPQQPGEAGLALPSNMDVSGPVLTPTAMTTLVP---------------PTECCLLSQTQLPSSWFPTQIPLVPWHPWDLQPLPGPLTQHP----------------------------------------------CVPTF-MFPPLHPKWGSICATST----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M1V0-1", "uniprot_id": "ISX_HUMAN", "id": "Q2M1V0-1", "name": "Intestine-specific homeobox", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEK----------IGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP---------------PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQT----------------------------------------------CIPVLCILPPPHPKWGSICATST----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75360-1", "uniprot_id": "PROP1_HUMAN", "id": "O75360-1", "name": "Homeobox protein prophet of Pit-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAERRRQAEKPKKGRVGSNLLP-ERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERS---------LLQPLAHLSPAAFSSFLPESTACPYSYAAPPPPVTCFP---------------HPYSHALPSQPSTGGAFALSHQSEDWYPTLHPAPAGHLPCPP----------------------------------------------PPPMLPLSLEPSKSWN-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTX7-1", "uniprot_id": "Q9VTX7_DROME", "id": "Q9VTX7-1", "name": "", "aln": "MLIEPTLNRDLGSLTVANSGLSAAHWKMEPHPQRITSLAPHASSVAAASVAAAAAAAAAAAAAAAGAGSGAVAGGGGATSTSPTSVQIPPGFGGGGSTGGIPHGAGGPTGSTLNTLMSQHRLLEFSRFGGLRGYDIAQHMLTQQGAVSKLLGSLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLISEGVCTNATAPSVSSINRILRNRAAERVATEFARTAAYGLYPPPPHPYGSFTWHPAGNVPGGQGVPPPPPPSALWSVAAPTLANLPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPANPLHSQQSNDAPASSPTPSNHSSASTSAPVAPVPPPQQPLPLCGDHSPQGPPPSVLLHPLHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQQQHHQQQQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLGLARQYAVAASLTVAEEQRSRLHYSAGGLGSGGEGTGPNTNTTQSGGSTMTVDNSSSDSDEEINVHDDSDGEIESSAATAAKVARLSSSDAPATLQFLKHDR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . . . : . . . .. . ** ****:. **.:**. * .:** : *. *: .*.***:*:**.*:*** *:::: . . * . :.. * . . ... . :* . * .: ", "identical_positions": 32, "similar_positions": 48, "identity": "4.78%" }, { "cls_id": "homologset.agr.FB:FBgn0000629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHI4-1", "uniprot_id": "A0A8I6AHI4_RAT", "id": "A0A8I6AHI4-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "MRIIMGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEWKQRRIQPVHIMTSVSSLRGTRECSVTSDL-DFPAQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECG----FINDEIFVELVNALG-QYNDDDDD-------------------DDGD-----DPDER------EEK-QKDLDDSRDDK-----ETC------------PPRKFPADKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNTYKRKNTETALDNKPCGPQCYQHLEG---AKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPVPTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61188-1", "uniprot_id": "EZH2_MOUSE", "id": "Q61188-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "----MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEWKQRRIQPVHIMTSVSSLRGTRECSVTSDL-DFPAQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECG----FINDEIFVELVNALG-QYNDDDDD-------------------DDGD-----DPDER------EEK-QKDLEDNRDDK-----ETC------------PPRKFPADKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNTYKRKNTETALDNKPCGPQCYQHLEG---AKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPVPTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15910-1", "uniprot_id": "EZH2_HUMAN", "id": "Q15910-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "----MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDL-DFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECG----FINDEIFVELVNALG-QYNDDDDD-------------------DDGD-----DPEER------EEK-QKDLEDHRDDK-----ESR------------PPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNTYKRKNTETALDNKPCGPQCYQHLEG---AKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPP---------ENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BS4-1", "uniprot_id": "EZH2_DANRE", "id": "Q08BS4-1", "name": "Histone-lysine N-methyltransferase EZH2", "aln": "----MGLTGRKSEKGPVCWRRRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTDILNQEWKLRRIQPVHIMTPVSSLRGTRECTVDSGFSEFSRQVIPLKTLNAVASVPVMYSWSPLQQNFMVEDETVLHNIPYMGDEILDQDGTFIEELIKNYDGKVHGDRECG----FINDEIFVELVNALN-QYSDNEED-------------------DEED-----DHHDY------KFE-KMDLCDGKDDA-----EDHKEQLSSESHNNDGSKKFPSDKIFEAISSMFPDKGSTEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFQ--ATPNTYKRKNMENLVDSKPCGIYCYMYMVQDGMVREYPAGVVPERAKTPSKRSTGRRRGRLPNSNSRPSTPTVNS-ETKDTDSDREGGAD-GNDSNDKDDDDKKDETTSSSEANSRCQTPVKLKLSSEPP---------ENVDWSGAEASLFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIARAPAVDENTPQRKKKRKHRLWATHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVTAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAAEHWDSKNVSCKNCSIQRGAKKHLLLAPSDVAGWGIFIKEPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LZH3-1", "uniprot_id": "F1LZH3_RAT", "id": "F1LZH3-1", "name": "[histone H3]-lysine(27) N-trimethyltransferase", "aln": "-VRKMDIASPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQLLNEEWKKLRVQPVQPMKPVSGHPFLKKCTIESIFPGFDSQDMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALN-QYSDEEEE-------------------GHND-----TSDGK------QDDSKEDLPVTRKRK-----RHAIE-----GNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNVYKRKNREIKIEPEPCGADCFLWLEG---AKEYAMLHNPR-----SKCSGRRRRRHPVVSASCSNTSASAMAETKEGDSDR---------------DTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKES-LILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNNSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCSPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70351-1", "uniprot_id": "EZH1_MOUSE", "id": "P70351-1", "name": "Histone-lysine N-methyltransferase EZH1", "aln": "----MDIASPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQPMKPVSGHPFLKKCTIESIFPGFDSQDMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALN-QYSDEEED-------------------GHND-----PSDGK------QDDSKEDLPVTRKRK-----RHAIE-----GNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNVYKRKNKEIKIEPEPCGTDCFLLLEG---AKEYAMLHNPR-----SKCSGRRRRRHPVVSASCSNASASAMAETKEGDSDR---------------DTGNDWASSSSEANSRCQTPTKQKASPAPAQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKES-LILKLPTDELMNPAQKKKRKHRLWAAHCRKIQLKKDNNSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCSPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92800-1", "uniprot_id": "EZH1_HUMAN", "id": "Q92800-1", "name": "Histone-lysine N-methyltransferase EZH1", "aln": "----MEIPNPPTSKCITYWKRKVKSEYMRLRQLKRLQANMGAKALYVANFAKVQEKTQILNEEWKKLRVQPVQSMKPVSGHPFLKKCTIESIFPGFASQHMLMRSLNTVALVPIMYSWSPLQQNFMVEDETVLCNIPYMGDEVKEEDETFIEELINNYDGKVHGEEEMIPGSVLISDAVFLELVDALN-QYSDEEEE-------------------GHND-----TSDGK------QDDSKEDLPVTRKRK-----RHAIE-----GNKKSSKKQFPNDMIFSAIASMFPENGVPDDMKERYRELTEMSDPNALPPQCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH--ATPNVYKRKNKEIKIEPEPCGTDCFLLLEG---AKEYAMLHNPR-----SKCSGRRRRRHHIVSASCSNASASAVAETKEGDSDR---------------DTGNDWASSSSEANSRCQTPTKQKASPAPPQLCVVEAPSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKES-LILKLPTDELMNPSQKKKRKHRLWAAHCRKIQLKKDNSSTQVYNYQPCDHPDRPCDSTCPCIMTQNFCEKFCQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYSQADALKYVGIERETDVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42124-1", "uniprot_id": "EZ_DROME", "id": "P42124-1", "name": "Histone-lysine N-methyltransferase E(z)", "aln": "---------MNSTKVPPEWKRRVKSEYIKIRQQKRYKRADEIKEAWIRNWDEHNHNVQDLYCESKVWQAKPYDPPH-VDCVKRAEVTSYNGIP--SGPQKVPICVINAVTPIPTMYTWAPTQQNFMVEDETVLHNIPYMGDEVLDKDGKFIEELIKNYDGKVHGDKDPS----FMDDAIFVELVHALMRSYSKELEEAAPGTATAIKTETLAKSKQGEDDGVVDVDADGESPMKLEKTDSKGDLTEVEKKETEEPLETEDADVKPDVEEVKDKLPFPAPIIFQAISANFPDKGTAQELKEKYIELTEHQDP-ERPQECTPNIDGIKAESVSRERTMHSFHTLFCRRCFKYDCFLHRLQGHAGPNLQKRRYPELKPFAEPCSNSCYMLIDG---MKEKLAADSKT-----------PPIDSCNEASSEDSNDSNSQFSNKDFNHEN----------------SKDNGLTVNSAAVAEINSIMAGMMNITST----------QCVWTGADQALYRVLHKVYLKNYCAIAHNMLTKTCRQVYEFAQKEDAEFSFEDLRQDFTPPRKKKKKQRLWSLHCRKIQLKKDSSSNHVYNYTPCDHPGHPCDMNCSCIQTQNFCEKFCNCSSDCQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCQACG-ADQFKLTKITCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDHRIGIFAKRAIQPGEELFFDYRYGPTEQLKFVGIEREMEIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *:::*****:::** ** : * : * : ...: * * * : :* . *. . : . * : : :*:*: :* **:*:* ************ ********: ::* .******:********:.: ::.* :*:***.** .*..: :: .. * . : . : ** .. . ** **.**:: **::* .:::**:* **** . * * :******* :*:**.**:::******************* :: * ** **: * :**. *: : :* * . : ..*: : :. .: : .* * :. :: . .. *:**: :::**: .* .*:*:**: : ****:**::* **. : : .* :***:*:***: **********..*.:**** ***** :*** .*.*: :********:*..:***********:********************* :** ::::. . ::*** .:*** :****:****:**** *:*: .************:*****************.***************************:********:**.**************.**********. :: **:****** :: ", "identical_positions": 348, "similar_positions": 169, "identity": "42.54%" }, { "cls_id": "homologset.agr.FB:FBgn0000633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB13A3N4-1", "uniprot_id": "A0AB13A3N4_DANRE", "id": "A0AB13A3N4-1", "name": "", "aln": "MKRAISGPFWICCTLLAVVLQVCLASVTVKVNPEMHVLKGDTVMLPCTYTTS-----AEAAVAVQWFIEFADGGRKQVAYKSSVGSDAG-----------TFTDRYTIEKDMSLNISQVTVDDHKKFICQVTAGPVGTAESATEVKVFS--------------------------------APEKPMVVPNPQKIFVDSSISSSAEVGKCIS------RNGHPEPRIIWFKDDNPLPEE---------KKKTEKTYMIHFLVKEASGLYTLTSMLYMHLTKADAKSVYHCIVEYT-------------------MPDNQIKQESSDNFNISLQYSTENVFFKVKNE--------GPIKEGDDVVMQCETDG-NPQP------------------------QFDFFKGE-------KLLEGLGGTLKKKSITREDSGTYKCEAMDYEADSKVQLHKTLNINVHYIDITVEPEGP---LVVSKGDHVELQCKAKASEAHTLQWTKDSKE----LSNTGVFAKESVTLADGGVYVCVG-----AVPSVPGLQKQVNITVNVKGQPE---------IDAPVKG-LVDKEGGMVTLNCS----------------------ALGHPAPQF-----------IWTPSGKESVTVKGNRVISTVTLEATAAVLKDGVICEAYNTHGRDSKNFEVKLDQAKPTPANSDRGNPDFKTVEGKQGGSSSVVIAVVVCVLLLLILVASLFFLNKKGKLG-------------------CGKKDQKEVASGGVKDNIVVEIKPSEKSKEEAGLLKPAEQC-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9G5-1", "uniprot_id": "A1Z9G5_DROME", "id": "A1Z9G5-1", "name": "", "aln": "MRPTFDRRLWILLFIISVQCTTYTQPQNINAKSVQKPKPSERREVISTSSSSSHSWPSISAEPADEVVDHRGGGKPAKCAKNCQKAKAKWAKWRTQLKPHHQAHRAVQHKEARQRQRRETEEDELDAVLRAPSSTSTSTAVATTVQATSSSSSATRSSVINETKAKRPRSTLHLAPEDMQPKPKEPVIIIDDVEEFDSGTSTSDLIARKSREEAEEEEDEGPLEPRVLPLRPVPPNPYEAEEMSVVYAEQHSEIKLMCEVDLDIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGALTITNVMLEDDGKWQCEAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARILCVMEHPT-LKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQKDDGDTPVPQTGDGFLNFTSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQCPQGSLGCWSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQSVTVSVKGAPTVMALNATPVAYPG---SPLHLNVEFCANPPAHAARWLHGDRVFTPGNQYGTTVLAYAVKDLPTPFCKEARLTYVSMHERVPRTFYFIVSTPGGVAEAIFNVNFTKRHRQLSNSIDDDEEEELNRPEQIHFPVFNGSPADGRGWWAVVLALLLVVATTNRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::. :** :::* . . .::.:. : .: : .* ::* : :* ..: .::. .**: . *.. :.* :.* . .*: . : * :*. . : :..:.. :: ** *:. * *::*::: : : * ..: :*. . *. . :* ***:: :: * * * ::::* . * .. :. *:.:: .. : : :: : *: * * . :.: *.: .:: : .: :: :... *:**..:: : * ::* **:* ::: :*** *: .* . : :: * . .: .*:: : *:: : :* ::*:* . .. * : :* .*.*:*...:. . * :* **. : :. *.: *: ..* * *.. .*: . :*:*..:*: . * ** * : ** ***:*. . .:*: ** ::. *:.... * .*:.:**:....* .: . . * . :.:::: . .**:: * . :.. : .::*: .* : : * * ::. : :: . ..::. *..:.*: *:: .*: : . .**: ", "identical_positions": 108, "similar_positions": 264, "identity": "13.08%" }, { "cls_id": "homologset.agr.FB:FBgn0000635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13596-1", "uniprot_id": "NCAM1_RAT", "id": "P13596-1", "name": "Neural cell adhesion molecule 1", "aln": "-------------MLRTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAG--DAKDKDISWFSPNGEKLSP-----NQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK--------ASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG---PVAVYTWEGNQVNITCEVFAYPS-ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSP-SIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGEISAATEFKTQPVR----------------EPSAPKLEGQMGEDGNS-----------IKVNLIKQDDGGSPIRHYLVKYRA-------LAS-EWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGK-AGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHT-EPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGPVETK--SEPQESEAKPAPTEVKTVPNEATQTKENESKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13595-1", "uniprot_id": "NCAM1_MOUSE", "id": "P13595-1", "name": "Neural cell adhesion molecule 1", "aln": "-------------MLRTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAG--DAKDKDISWFSPNGEKLSP-----NQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEE------------------KTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEFQYAPKLQG---PVAVYTWEGNQVNITCEVFAYPS-ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSP-SIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGEESWHFKWYDAKEANMEGIVTIMGLKPETRYSVRLAALNGKGLGEISAATEFKTQPVR----------------EPSAPKLEGQMGEDGNS-----------IKVNLIKQDDGGSPIRHYLVKYRA-------LAS-EWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGK-AGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHT-EPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATTVPDSNSVPAGQATPSKGVTASSSSPASAPKVAPLVDLSDTPTSAPSASNLSSTVLANQGAVLSPSTPASAGETSKAPPASKASPAPTPTPAGAASPLAAVAAPATDAPQAKQEAPSTKGPDPEPTQPGTVKNPPEAATAPASPKSKAATTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPRPATGASGQASELAPSPADSAVPPAPAKTEKGPVETK--SEPPESEAKPAPTEVKTVPNDATQTKENESKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13591-2", "uniprot_id": "NCAM1_HUMAN", "id": "P13591-2", "name": "Neural cell adhesion molecule 1", "aln": "-------------MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAG--DAKDKDISWFSPNGEKLTP-----NQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE-QEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK--------ASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG---PVAVYTWEGNQVNITCEVFAYPS-ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQG---------------EPSAPKLEGQMGEDGNS-----------IKVNLIKQDDGGSPIRHYLVRYRA-------LSS-EWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLSTGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGK-AGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHT-EPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGPVEAK--PECQETETKPAPAEVKTVPNDATQTKENESKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEP5-1", "uniprot_id": "A0AB32TEP5_DANRE", "id": "A0AB32TEP5-1", "name": "", "aln": "-------------MLQIRDLIWTLLFLGYAAALQVEITPTQGEISVGESKFFLCEVVG--DAK--EIDWFAPNGEKLLP-----GRPDISISKTDESSSTLTIYNANVDHAGMYKCVAKSGE-KESQGTIIVKIFQKLTFQYAPSPQEFNEGDDADIICDVISSPPPTIIWRYKKMRIQPETDVRLKVLSNNHLQIRGIKKTDEGDYTCEGRIMARGEIDLRVIKVIVNVLPSIRTRYTELNATADINQAVTLACHADGYPEPTVKWARGNTELE----SDEKYSLNEDGSELTIKDVNKLDEGDYKCIARNKAGERSEEVTLNVFVQPKITFLENQTASELEEQITLTCEATGDPTPNIIWSFGRRVFTENEQ--------ASWTRPEKHKSLDGNVVVRSDARVSSLTLKYVQFTDAGQYLCTARNSIGQDIQSMYLEVRYAPKIQG---PQAVFTWEGNPANITCEALAHPG-ASVLWFRDGQQLPSANTTNVKIYNTPTVSFLEVTPDSQNDFGSYNCTATNVIGTESKEFILVQADVPSAP-SIERVEPYSSTAMIEFEEPASSGGVPVLKYKAEWRIAGQD-WTDREYELEDG--LNLITIVGLKPETTYEVKISAINGKGEGESSAPESFKTQPVRLPFRR-----------EPNPPKLEAKPQSTGNE-----------MKVHFIKQDDGGSPIKHYLVRYRA-------KNRQDWKPEIRMPDASDYIVLRGLDWNTEYEVYVIAENQRGRSEPGTLSFRTLPEPTAIPETSS---GLGTGAIVGILIVVFILLLFGVDVTCYFLNKCGLLMCIAVNFCGK-SGPSAKSKDIEEGKAAFTKDESKEPIVEVRTEEERTPNHEGGGPT-EPNETTPLTDPEHAADTTATVVDLLPSVTTNSDPGTESPASDSTTLTTSTDPKPTPQSSTPKPSVTSPTSPPQAVAPLVDLSETPSKQTSKSLDDSSPAEVARADGQSPAEPAKAPQSKDSQVQAGSHQTTDSDPAKNSSDSSSAPSAPNQ-----------------------------------------------------------------------------------------------------------------------------DDGKIIVDDK--SKAPETEVKKPPAEVKTVPNEAPQANGNESKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B0V3-1", "uniprot_id": "A0A8M3B0V3_DANRE", "id": "A0A8M3B0V3-1", "name": "", "aln": "-------------MFPTKAIILVLLFFDNAVSLQVDITPAHGEISVGESRFFLCEVIG--GAK--EIDWFAPAGEKIEP-----GRPDISVIRNDETSSTLTIYNAKVDNAGTYRCVASSGD-QDAEATVNLKIYQKITFTNVPSPQEFTEGDNAIIVCDVISSPPPTVLWKYKGAKIQFDKDVRFKTLSNNHLQIRGIRKTDEGVYTCEGRIKARGEVDFRSIKVVVNVLPTIRIRQAETNATADMGFSTLLACDPDGFPEPIVTWRRNNAPLE----SGNKYSFNEDGSEMTVLDVTKLDEGDYTCIAKNKAGESEQELSLKVFVQPKITYLESQTTTEMDEQVTLTCEATGDPTPTITWSFGTRVFTEGEQEQQKRIYQASWTRPEQHKGPDGEVLVRSDARVSSLTLKYPQYTDAGQYLCTARNAIGETVQPVSLEVRYAPKILG---SVAVYTWEGNPANISCEVLAHPSDVSITWLRDGFQLPNANTSNIKIHNTPSASYLEVNPESQSDFGNYNCTTSNEIGTESREFIMIPADVPSAP-SIGEVQPYSSTAQVLFEEPESTGGVPVLKYRAEWRAVGRGKWVQRVYEVKDG--LSSVTVTGLKPETDYEVKMSAINGKGEGDSSPSMVFKTEHVRYSYTNGIFHFHTEDTGEPSPPILEGTLQPKGNS-----------LKVKWIKQDDGGSPITHYLVRYKA-------REDSEWKPEIRLPSGSEYVMLIGLDWDTEYDVFVVAENQQGKSKPGTLTFRTSSEPTATTDSMEDGPGLNTGVIVGILILVCVLLLLIVDATCCFLNKCGILMCI----CGK-PGQSTKGKDIETGKAAFVQDVSKEPIVEVRTEEEATANHDAEGHL-EPNETTPLTEPEQVTETAAAVVDLPLSVPTNSDTITDTFDLSQSSPVSESTTLTSSITAPPSDPINPVHMTPPDSSTPKTHSRPSISSSDPANVTLLVDLAEVSPAVPSEEPVQVPSSPTSVDHPGTIISKVTENESVQGPSHAALNPISPQGDIAVPLVNHELEIDGEHPLASDTDATQDGSHAGG-------------------------------------------------------------------------------------TAGSSGPSAPAQDEKILEDENAELKKVAPDAGFEPNAVTQTN-IESKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LEM6-1", "uniprot_id": "A0ABK0LEM6_RAT", "id": "A0ABK0LEM6-1", "name": "Neural cell adhesion molecule 2", "aln": "------------MTLFQNIVELPRIFKLIGALLQVTISLSKVELSVGESKFFTCTAIG--EPE--SIDWYNPQGEKIIS-----TQR--VMLQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVLSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTIPDNRFAVLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIVMPQKSFNATAERGEEMTLTCKASGSPDPAISWFRNGKLIE----ENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTSE-NGHVTLICEAEGEPVPEITWKRAIDGVTFSEG----------------DKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYAPKFVSN--QTMYYSWEGNPINISCDVKANPP-ASIHWRREKLVLPAKNTTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATNRIGTRFQEYILELADVPSSPRGVKIIELSQTTAKISFNKPESHGGVPIHHYQVDVKEVTSETWKIVRSHGVQT----TVVLSSLEPNTTYEVRVAAVNGKGQGDYSKIEIFQTLPVR----------------EPSPPSIHGQP-SSGKS-----------FKISITKQDDGGAPILEYIVKYRS-------KDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFN--GLGLGAIIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMCGKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERITNHEDGSPVNEPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPLKEE-----NGKEVLNAETIEIKVSNDIIQSKEDDIKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35136-1", "uniprot_id": "NCAM2_MOUSE", "id": "O35136-1", "name": "Neural cell adhesion molecule 2", "aln": "------------MSLLLSFYLLGLLVRSGQALLQVTISLSKVELSVGESKFFTCTAIG--EPE--SIDWYNPQGEKIIS-----TQR--VMLQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTIPDNRFAVLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPTISWFRNGKLIE----ENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTSE-NGHVTLVCEAEGEPVPEITWKRAIDGVMFSEG----------------DKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYAPKFVSN--QTMYYSWEGNPINISCDVTANPP-ASIHWRREKLLLPAKNTTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATNRIGTRFQEYILELADVPSSPHGVKIIELSQTTAKISFNKPESHGGVPIHHYQVDVKEVASETWKIVRSHGVQT----MVVLSSLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVR----------------EPSPPSIHGQP-SSGKS-----------FKISITKQDDGGAPILEYIVKYRS-------KDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFN--GLGLGAIIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMCGKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERITNHEDGSPVNEPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPLKEE-----NGKEVLNAETIEIKVSNDIIQSKEDDIKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15394-1", "uniprot_id": "NCAM2_HUMAN", "id": "O15394-1", "name": "Neural cell adhesion molecule 2", "aln": "------------MSLLLSFYLLGLLVSSGQALLQVTISLSKVELSVGESKFFTCTAIG--EPE--SIDWYNPQGEKIIS-----TQR--VVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIE----ENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYE-NGQVTLVCDAEGEPIPEITWKRAVDGFTFTEG----------------DKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISN--QTIYYSWEGNPINISCDVKSNPP-ASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVRSHGVQT----MVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVR----------------EPSPPSIHGQP-SSGKS-----------FKLSITKQDDGGAPILEYIVKYRS-------KDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFN--GLGLGAVIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMCGKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERVTNHEDGSPVNEPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLPLKEE-----DGKEALNPETIEIKVSNDIIQSKEDDSKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34082-1", "uniprot_id": "FAS2_DROME", "id": "P34082-1", "name": "Fasciclin-2", "aln": "MGELPPNSVGVFLALLLCSCSLIELTRAQSPILEIYPKQEVQRKPVGKPLILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMITSLSVEMGGKYYCTASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDK--YVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVE--GKPFAANCTARGKPVPEISWIRDATQLN--VATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGAR-TKEIAITCRAKGRPAPAITFRRWGTQEEYTNG----------QQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPN-ATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSWSP--DSPYIVEGLRPQTEYSFRFAARNQVGLGNWGVNQQQSTPRRS----------------APEEPKPLHNPVQHDKEEPVVVSPYSDHFELRWGVPADNGEPIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIGYSSPASIIMKTTRGIDVIQVAERQ--VFSSAAIVGIAIGGVLLLLFVVDLLCCITVHMGVMATMCRKAKRS---PSEIDDEAKLGSGQLVKEPPPSPLPLPPP-----VKLGGSPMSTPLDEKEPLRTPT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSIKQN-------STIEFDGRFVHSRSGEIIGKNSAV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:: . .**:. :: * . .:.* .:.: . : * * . .:: .* * * .. . : : :: : : : . * *:: ::* * :. *:: * : : * : .* * * .:.::*** * *.. : **: : * * * : * : :*. . * . * * * :.* :. :: ::. .. . :*: .: : * . * * * *:** . *:*:.:*:* : . * . .::: * * * * * * : : : .. . .:* : : :* * * * * . . :. : ..:**.: ::** . *::* . . * .:: * : : :::* .. * : * : . :. *:* : * * : : * .*. : :* . : * : *:*: * .: : * . : .*.*:* * .:.:* * * *: . .* *. * .:. ::: *.* ** .* ::* . : : . . : * * : : * * * *.. : :. ..::*: : :*:*. * * : : *:: : . . ..: : *.. :: . .*: . : :*. ** * . : .. : ", "identical_positions": 120, "similar_positions": 227, "identity": "10.03%" }, { "cls_id": "homologset.agr.FB:FBgn0000636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1WIM3-1", "uniprot_id": "CADM3_RAT", "id": "Q1WIM3-1", "name": "Cell adhesion molecule 3", "aln": "----------------------------------MGAPSA--LPLLLLLACSWAPGG---------ANLSQDDS--QPWTSDETVVAGGTVVLKCQVKDHE----DSSLQWSNPA----------QQTLYFGEKR-ALRDNRIQLVSS--------TPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKET------ATLNCQSSGSKPAAQLAWRKGDQELHGDQTRIQED-PNGKTFTVSS---SVSFQVTRDDDGANVVCSVNHESLKGAD-RSTSQR-IEVLYTPTAMIRPEPA---HPREGQKLLLHCEGRGNPVPQQYVWV-KEGSE----------PPLK--MTQESALIFPFLNKSDS-GTYGCTATSNMGSYTAYFTLNVND-----------------------------------------------------------------------------------------------------PSPVP----------------------------------------SSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRH---KGTYLTHEAKGSDD--------------APDADTAIINAEGGQSGGDDKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N28-1", "uniprot_id": "CADM3_MOUSE", "id": "Q99N28-1", "name": "Cell adhesion molecule 3", "aln": "----------------------------------MGAPSA--LPLLLLLACSWAPGG---------ANLSQDDS--QPWTSDETVVAGGTVVLKCQVKDHE----DSSLQWSNPA----------QQTLYFGEKR-ALRDNRIQLVSS--------TPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKET------ATLNCQSSGSKPAAQLTWRKGDQELHGDQTRIQED-PNGKTFTVSS---SVSFQVTREDDGANIVCSVNHESLKGAD-RSTSQR-IEVLYTPTAMIRPEPA---HPREGQKLLLHCEGRGNPVPQQYVWV-KEGSE----------PPLK--MTQESALIFPFLNKSDS-GTYGCTATSNMGSYTAYFTLNVND-----------------------------------------------------------------------------------------------------PSPVP----------------------------------------SSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRH---KGTYLTHEAKGSDD--------------APDADTAIINAEGGQSGGDDKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N126-1", "uniprot_id": "CADM3_HUMAN", "id": "Q8N126-1", "name": "Cell adhesion molecule 3", "aln": "----------------------------------MGAPAASLLLLLLLFACCWAPGG---------ANLSQDDS--QPWTSDETVVAGGTVVLKCQVKDHE----DSSLQWSNPA----------QQTLYFGEKR-ALRDNRIQLVTS--------TPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDT------ATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED-PNGKTFTVSS---SVTFQVTREDDGASIVCSVNHESLKGAD-RSTSQR-IEVLYTPTAMIRPDPP---HPREGQKLLLHCEGRGNPVPQQYLWE-KEGSV----------PPLK--MTQESALIFPFLNKSDS-GTYGCTATSNMGSYKAYYTLNVND-----------------------------------------------------------------------------------------------------PSPVP----------------------------------------SSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRH---KGTYLTHEAKGSDD--------------APDADTAIINAEGGQSGGDDKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H5F7-1", "uniprot_id": "A0AC58H5F7_DANRE", "id": "A0AC58H5F7-1", "name": "", "aln": "-------------------------MSGMRARQTLAFPSFQRAALRALAAFTMILATS------VRSNYVYDDDPFQPVTQDETVAVGGVVTLTCGVKEND----NSSLQWSNTA----------QQTLYFGEKR-ALRDNRIQLVKS--------TATELIITIGDVQLSDDGEYTCSIFTMPVRTARATVTVLGVPGKPVITGFEGAVQEGGK------VTLTCTSSGSKPPAKLHWYRDHVEIQGRPDVVESN-PNEPTYTVTS---ELTLSVSRDDNDALIACAVDHPSIANGD-KRTEQP-LNVLFSPRVSIHPESD---LPREGEKFYLQCVGNGNPEPNAFVWRRKEGEL----------PPLA--KVDGAFLRFESLNKSDN-GVYECQADNGIGMGDVAHTLLVQEGDPDYLIPSFTLPSSTVSPTSLSQTSVLPSTEGETLPPTSSSSSSTVIPTFTLPIPSTPSAPPTVPPSPESPTTALSNALFPELTPPAYTPPSTPTIPPATPSSVPRLNGVYTFTEAGEN------------------AADPTAMSTGSGVDHAVIGGVVAVIVFIMLCLLLVLGRYLIRH---KGTYLTHEAKGSDD--------------APDADTAIINAEGGHSGVDDKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N3J6-1", "uniprot_id": "CADM2_HUMAN", "id": "Q8N3J6-1", "name": "Cell adhesion molecule 2", "aln": "------------------------------------MIWKRSAVLRFYSVCGLLLQ---------------GSQGQFPLTQNVTVVEGGTAILTCRVDQND----NTSLQWSNPA----------QQTLYFDDKK-ALRDNRIELVRA--------SWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL------MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED-ANRKTFTVSS---TLDFRVDRSDDGVAVICRVDHESLNATP-QVAMQV-LEIHYTPSVKIIPSTP---FPQEGQPLILTCESKGKPLPEPVLWTKDGGEL----------PDPDRMVVSGRELNILFLNKTDN-GTYRCEATNTIGQSSAEYVLIVHD-----------------------------------------------------------------------------------VPNTLLPTTIIPSLTTATVTTTVAITTSPTTSATTSS------------------IRDPNALAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARH---KGTYLTNEAKGAED--------------APDADTAIINAEGSQVNAEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BLQ9-1", "uniprot_id": "CADM2_MOUSE", "id": "Q8BLQ9-1", "name": "Cell adhesion molecule 2", "aln": "------------------------------------MIWKRSAVLRFYSVCGLLLQ---------------GSQGQFPLTQNVTVVEGGTAILTCRVDQND----NTSLQWSNPA----------QQTLYFDDKK-ALRDNRIELVRA--------SWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL------MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED-ANRKTFTVSS---TLDFRVDRSDDGVAVICRVDHESLNATP-QVAMQV-LEIHYTPSVKIIPSTP---FPQEGQALTLTCESKGKPLPEPVLWTKDGAEL----------PDPDRMVVSGRELNILFLNKTDN-GTYRCEATNTIGQSSAEYVLIVHD-----------------------------------------------------------------------------------VPNTLLPTTIIPSLTTAPVTTSVTITTSPSTSASSSS------------------RRDPNSLAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARH---KGTYLTNEAKGAED--------------APDADTAIINAEGSQVNAEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBX7-1", "uniprot_id": "A0ABK0LBX7_RAT", "id": "A0ABK0LBX7-1", "name": "Cell adhesion molecule 2", "aln": "------------------------------------VVWANDFKLFFY-----IFQ---------------G---QFPLTQNVTVVEGGTAILTCRVDQND----NTSLQWSNPA----------QQTLYFDDKK-ALRDNRIELVRA--------SWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL------MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEED-ANRKTFTVSS---TLDFRVDRSDDGVAVICRVDHESLNATP-QVAMQV-LEIHYTPSVKIIPSTP---FPQEGQALTLTCESKGKPLPEPVLWTKDGAEL----------PDPDRMVVSGRELNILFLNKTDN-GTYRCEATNTIGQSSAEYVLIVHD-----------------------------------------------------------------------------------VPNTLLPTTIIPSLTTAPVTTTVAITTSPSTSASSSS------------------RRDPNSLAGQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARH---KGTYLTNEAKGAED--------------APDADTAIINAEGSQVNAEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B1M0-1", "uniprot_id": "A0A8M2B1M0_DANRE", "id": "A0A8M2B1M0-1", "name": "", "aln": "------------------------------------MMVKQHMLFTLYSICGIVLKDILAVSVAATKNKVRGAQGQVPLVQNMTVTEGGTANLTCRVEHND----NTSLQWSNPA----------QQTLFFGDKK-ALRDNRIELVRA--------TSQELTISISEVSLSDEGLYTCSLFTMPVKTAKAFLTVLGVPKKPEINGLTKPVLEGDH------ITLTCVTSGSKPAADVRWFKNEMEVKG---AKEVN-ASGKTFTVKS---SLRLHVNRDDDGVAYTCRVDHVALTATH-EETTQV-LEVHYAPYVEIRQSTN---VPQEGQYLKLQCVPKGNPSPDPVLWTKDGGEL----------PDMDRMIVDGRDLTFTSLNKTDN-GTYRCEATNHLGTSHAEFKLVIYD-----------------------------------------------------------------------------------APTTPSPSTTSP---APTLPDTTGPLDSKQLNSAVTG------------------NRDPNELKR--ATDHALIGGIVAVVVFATLCLIIVLGRYLARH---KGTYLTNEAKGADD--------------APDADTAIINADGNHAHAEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B3K2-1", "uniprot_id": "A0A8M2B3K2_DANRE", "id": "A0A8M2B3K2-1", "name": "", "aln": "------------------------------------MMLQQHLLFVLYSFCGIVIK------EAATKNKVKGSQAQFPITQNVTVVEGSTANMTCRVDYND----NTSLQWSNPA----------QQTLFFGDKK-ALRDNRIELVRA--------SWKELTISISDVALSDEGQYTCSLFTMPVKTSKAFLTVLGVPAKPEITGLSRPAQEGED------VTLTCTTSGSKPAADIRWFRNDKEVQAG--QKEVN-ATGRSFTVRS---SVHLKVDRKDDGAAYTCVVEHVTLGSLP-HQVTEV-LEVHYPPQVKIVHSVI---VPQEGQYFKLECMSKGNPLPEPVMWTKDGGEL----------PDIERMIVEGRDLIITTLNKTDN-GTYRCEASNHLGTNRDEFVLYVY---------------------------------------------------------------------------------------------------AKDFPGTT---------------------------------TDPNALTQH-GPDHALIGGVVAVVVFITLCFIIVLGRYLARH---KGTYLTNEAKGAED--------------APDADTAIINAEGNHAHAEEKKEYYQGAARNVVHLKSENLG----------------FANNYALRQEYVRCIM-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AYP5-1", "uniprot_id": "CADM1_RAT", "id": "Q6AYP5-1", "name": "Cell adhesion molecule 1", "aln": "--------------------MASPVLPSGSQCAAAAAVAAAAAPPGLRLRLLLLLLS--------AAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSD----DSVIQLLNPN----------RQTIYFRDFR-PLKDSRFQLLNF--------SSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEE------IEVNCTAMASKPATTIRWFKGNKELKGK--SEVEE-WSD-MYTVTS---QLMLKVHKEDDGVPVICQVEHPAVTG-N-LQTQRY-LEVQYKPQVQIQMTYPLQGLTREGDAFELTCEATGKPQPVMVTWVRVDDEM----------PQHA--VLSGPNLFINNLNKTDN-GTYRCEASNTVGKAHSDYMLYVYDP--------------------------------------------------------------------------------PTTIPPPTTTTTTTTTTTTTTTILTIITDTTATTEPAVHGLTQLPNSAEELDSEDLSDSRAGEEGAIGAVDHAVIGGVVAVVVFAMLCLLIILGRYFARH---KGTYFTHEAKGADD--------------AADADTAIINAEGGQNNSEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5M8-1", "uniprot_id": "CADM1_MOUSE", "id": "Q8R5M8-1", "name": "Cell adhesion molecule 1", "aln": "--------------------MASAVLPSGSQCAAAAAVAAAAAPPGLRLRLLLLLLS--------AAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSD----DSVIQLLNPN----------RQTIYFRDFR-PLKDSRFQLLNF--------SSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEE------IEVNCTAMASKPATTIRWFKGNKELKGK--SEVEE-WSD-MYTVTS---QLMLKVHKEDDGVPVICQVEHPAVTG-N-LQTQRY-LEVQYKPQVHIQMTYPLQGLTREGDAFELTCEAIGKPQPVMVTWVRVDDEM----------PQHA--VLSGPNLFINNLNKTDN-GTYRCEASNIVGKAHSDYMLYVYDP--------------------------------------------------------------------------------PTTIPPP--TTTTTTTTTTTTTILTIITDTTATTEPAVH------------------DSRAGEEGTIGAVDHAVIGGVVAVVVFAMLCLLIILGRYFARH---KGTYFTHEAKGADD--------------AADADTAIINAEGGQNNSEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY67-1", "uniprot_id": "CADM1_HUMAN", "id": "Q9BY67-1", "name": "Cell adhesion molecule 1", "aln": "--------------------MASVVLPSGSQCAAAA---AAAAPPGLRLRLLLLLFS--------AAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSD----DSVIQLLNPN----------RQTIYFRDFR-PLKDSRFQLLNF--------SSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEE------IEVNCTAMASKPATTIRWFKGNTELKGK--SEVEE-WSD-MYTVTS---QLMLKVHKEDDGVPVICQVEHPAVTG-N-LQTQRY-LEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEM----------PQHA--VLSGPNLFINNLNKTDN-GTYRCEASNIVGKAHSDYMLYVYDP--------------------------------------------------------------------------------PTTIPPP--TTTTTTTTTTTTTILTIITD-----------------------------SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARH---KGTYFTHEAKGADD--------------AADADTAIINAEGGQNNSEEKKEYFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NF64-1", "uniprot_id": "A0A8M1NF64_DANRE", "id": "A0A8M1NF64-1", "name": "", "aln": "-------------------------MKQVSNMANTSN--GSLATLLILITISAAIHT--------GAAQYPVQS-QNLISDNVSVVEGETATISCRVKNND----DSVIQLLNPN----------RQTIYFKDVR-PLKDARFQLVNF--------SDNELRVSLSNVSLSDEGRYVCQLYTDPPQEAYADITVLIPPGNPIIESREDIVSEGNE------TEITCTSMGSKPAATIRWMKGDKELQGK--SKVEL-TYDKMFTVTS---WLRLTVTREDDGVPVVCIVDHPAVK--D-FQAQKY-LEVQYKPEVQIVVDFP-SGPIREGENLELTCLAKGKPEPQQVNWVRVDDDV----------PSHA--VITGSDLFIENLNKSYN-GTYRCVASNPLGEAYDDYILFVRDA--------------------------------------------------------------------------------LTTTPIP--TTTTTTTISATTSPPDVIQDAAPSTEAAAH------------------DSQAGAE-TQRSMDHALIGGVVAVVVFAMLCLLIVLGRYFARH---KGTYFTHEAKGADD--------------AADADTAIINAEGGHNNSDEKKEYYI----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1WIM1-1", "uniprot_id": "CADM4_RAT", "id": "Q1WIM1-1", "name": "Cell adhesion molecule 4", "aln": "------------------------------------MGRARRFQWPLLLLWAAAAGP---------------GTAQEVQTENVTVAEGGVAEITCRLHQYD----GSIVVIQNPA----------RQTLFFNGTR-ALKDERFQLEEF--------SPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAV-EGGE------VELSCLVPRSRPAAVLRWYRDRKELKG---VSSGQ-ENGKVWSVAS---TVRFRVDRKDDGGIVICEAQNQALPSGH-SKQTQYVLDVQYSPTARIHASQA---VVREGDTLVLTCAVTGNPRPNQIRWNRGNESL----------PERA--EALGETLTLPGLVSADN-GTYTCEAANKHGHARALYVLVVY--------------------------------------------------------------------------------------------------------------------------------------------DPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQ---KGSYLTHEASGLDE--------------QGEAREAFLNGSDGHKR---KEEFFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R464-1", "uniprot_id": "CADM4_MOUSE", "id": "Q8R464-1", "name": "Cell adhesion molecule 4", "aln": "------------------------------------MGRARRFQWPLLLLWAAAAGP---------------GTGQEVQTENVTVAEGGVAEITCRLHQYD----GSIVVIQNPA----------RQTLFFNGTR-ALKDERFQLEEF--------SPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAV-EGGE------VELSCLVPRSRPAAVLRWYRDRKELKG---VSSGQ-ENGKVWSVAS---TVRFRVDRKDDGGIVICEAQNQALPSGH-SKQTQYVLDVQYSPTARIHASQA---VVREGDTLVLTCAVTGNPRPNQIRWNRGNESL----------PERA--EAVGETLTLPGLVSADN-GTYTCEAANKHGHARALYVLVVY--------------------------------------------------------------------------------------------------------------------------------------------DPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQ---KGSYLTHEASGLDE--------------QGEAREAFLNGGDGHKR---KEEFFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFZ8-1", "uniprot_id": "CADM4_HUMAN", "id": "Q8NFZ8-1", "name": "Cell adhesion molecule 4", "aln": "------------------------------------MGRARRFQWPLLLLWAAAAGP---------------GAGQEVQTENVTVAEGGVAEITCRLHQYD----GSIVVIQNPA----------RQTLFFNGTR-ALKDERFQLEEF--------SPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAV-EGGE------VELSCLVPRSRPAATLRWYRDRKELKG---VSSSQ-ENGKVWSVAS---TVRFRVDRKDDGGIIICEAQNQALPSGH-SKQTQYVLDVQYSPTARIHASQA---VVREGDTLVLTCAVTGNPRPNQIRWNRGNESL----------PERA--EAVGETLTLPGLVSADN-GTYTCEASNKHGHARALYVLVVY--------------------------------------------------------------------------------------------------------------------------------------------DPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQ---KGSYLTHEASGLDE--------------QGEAREAFLNGSDGHKR---KEEFFI----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HGB3-1", "uniprot_id": "A0AC58HGB3_DANRE", "id": "A0AC58HGB3-1", "name": "Cell adhesion molecule 4", "aln": "--------------------MSKHHCGLHGEPAIVLLHSAVELAIKLQSSNLSVPST---------------SRGQAVQAENVTVLEGGTAQISCRLQNYD----GSIVVIQNPR----------RQTLFFNGTR-ALKDDRFQMVLF--------TPKLVRITLTNVSVSDEGGYFCQLYTDDTHHQVATLSVVVPPEVPSVEVKTEAV-EGGE------VELTCLSLRSKPPATLRWVRDRREIPG---VISQQ-ENGKTVSVSN---TIRIPVERKDNRAALSCEASHPALVS-Q-KRVRHYSLDVHFAPTVKIVPPQG---ILREGDSLSLTCSVTGNPLPRDIQWSRVNDTL----------PERA--EKTGNILHMSRLSQSHN-GTYLCQAHNNYGRAADHYTLLVYVS---------------------------------------------------------------------------------------------------VAQSHPAIAHPNLPSSKEYQ-------------------DPGAVVETHSAVPFAVIGGILALLVFTVICVLIVTIWCSVRQ---KGSYLTHEASGLDE--------------HGEVQEAFLNGNDASQG---KKEYLL----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LNP8-1", "uniprot_id": "F1LNP8_RAT", "id": "F1LNP8-1", "name": "Nectin-1", "aln": "-----------------------------MARMGLAGAAGRWWGLALGLTAFFLPG---------------THTQVVQVNDSMYGFIGTDVILHCSFANPLPTVKITQVTWQKAS-NGSKQNMAIYNPTMGVSVL-PPYEKRVEFLRP--------SFIDGTIRLSHLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRARKGQDDKVLVATCTSANGKPPSVVSWET---RLKGEAEYQEIR-NPNGTVTVIS---RYRLVPSREAHRQSLACIVNYHLDR-----FRESLTLNVQYEPEVTIEGFDGN--WYLQRTDVKLTCKADANPPATEYHWTTLNGSL----------PKGVE-AQNRTLFFRGPINYSLA-GTYICEATNPIGTRSGQVEVNITEF--------------------------------------------------------------------------------------------------PYTPTP-------------------------------------EHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKGDYSTKKHVYGNG-------YSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEE-----------GGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQ-------------------LDLAENMVSQNDGSFISKKEWYV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKF6-1", "uniprot_id": "NECT1_MOUSE", "id": "Q9JKF6-1", "name": "Nectin-1", "aln": "-----------------------------MARMGLAGAAGRWWGLALGLTAFFLPG---------------THTQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKAS-NGSKQNMAIYNPTMGVSVL-PPYEKRVEFLRP--------SFIDGTIRLSGLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTNWIEGTRAVLRARKGQDDKVLVATCTSANGKPPSAVSWET---RLKGEAEYQEIR-NPNGTVTVIS---RYRLVPSREAHRQSLACIVNYHLDR-----FRESLTLNVQYEPEVTIEGFDGN--WYLQRTDVKLTCKADANPPATEYHWTTLNGSL----------PKGVE-AQNRTLFFRGPITYSLA-GTYICEATNPIGTRSGQVEVNITEF--------------------------------------------------------------------------------------------------PYTPTP-------------------------------------EHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKGDYSTKKHVYGNG-------YSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEE-----------GGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQ-------------------LDLAENMVSQNDGSFISKKEWYV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15223-1", "uniprot_id": "NECT1_HUMAN", "id": "Q15223-1", "name": "Nectin-1", "aln": "-----------------------------MARMGLAGAAGRWWGLALGLTAFFLPG---------------VHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKST-NGSKQNVAIYNPSMGVSVL-APYRERVEFLRP--------SFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWET---RLKGEAEYQEIR-NPNGTVTVIS---RYRLVPSREAHQQSLACIVNYHMDR-----FKESLTLNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSL----------PKGVE-AQNRTLFFKGPINYSLA-GTYICEATNPIGTRSGQVEVNITEF--------------------------------------------------------------------------------------------------PYTPSPP------------------------------------EHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNG-------YSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEEE----------GGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQ-------------------LDLAENMVSQNDGSFISKKEWYV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B818-1", "uniprot_id": "NEC1A_DANRE", "id": "A0A8M2B818-1", "name": "Nectin 1a", "aln": "---------------------------------------MMFINLLLRLMCVFLIG---------------ADGQMVQMESSKAGFVGSQVELPCQFVNSNPPVKISQVTWQKLV-NGTKQNVAIANPALGVSVL-NPFRERVRFKNPAVRQRTP-SLEDTTIVFNRLKLTDESTYICEYTTFPAGNRENMVNLTVFARPMIQMSLSTPSIVAGS-KDLKMTVATCVSANGKPASVITWET---DLDGESNTQEIS-NPDGTVTVRS---DYFVVPSREIHQQLLTCISTYNEEQ-----YTDSVTLNIQYEPEVIIEGFDGN--WYLNRENVQLTCLADANPTISLYQWRYLNGTL----------PSSAE-LRDDVLIFKGPVTYDIA-GTYVCDATNSIGSGSASVEVIVTEF--------------------------------------------------------------------------------------------------PSYPH---------------------------------------EVFQDQQQAGVVIGGAVVCGTVLLAAVTLLVVFLYRRRCMFKGDYSTKKQILGNG-------YSKAGNVPSHPSLPHSLTFSDDSDEEKKLELYRGSSILGGSVQE-----------------------FHTCHDSRIKAYRTGLIEEHERCAFNEQTYIYEYGSE--------------------VEVSVDMIPQMDGSVISKEEWYV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0JYH6-1", "uniprot_id": "NEC1B_DANRE", "id": "B0JYH6-1", "name": "Nectin 1b", "aln": "MDKQESFFVGHKSHRCSQNRSVSQIHQRTSRLSECYTVPLQWPHGIVWHNNNSLLKGL-----------EAGNGQSVQTDPSKSGFVGDTVELKCLFINGKPPVKISQVTWQKLI-NGTKQNVAIANPALGVSVL-TPFKDRVSFKHPAVRQRTPSSLEDTTIVFSSLRLSDEAAYICEYTTFPAGNRENMVNLTVFARPVTKMTLTSPTIVART-PKRKMPVATCMSANGKPPSVIKWDT---TLKGEATFQETR-NPNGTVTVRS---NYIVLPSRETHRQKLTCIVTYRSER-----FTDSVILNVQYEPEVKIEGFDGN--WYLNRPNVQLTCNADANPPVTVYQWKLLNGSL----------PNNIE-IKNNTLFFKGPVTYELG-GTYVCEATNSIGTRSGLVEVNVTEL--------------------------------------------------------------------------------------------------PNIPFDE------------------------------------REIPAELHSSGAAIGGAVGGVALLVAAIALLVFFLRRRQRTFKGDYSTKKHVFGNG-------YSKAGGMPAHPPMPKNLQYPDDSDDEKKPAQISGPGGFESGDRD-----------------------FDGNSEDLKRPYFT--VDEGESRDYDERTLAFQYDPE--------------------PEIADDMVSQTDGSVISKKEWYV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A5C0-1", "uniprot_id": "D4A5C0_RAT", "id": "D4A5C0-1", "name": "Nectin-3", "aln": "--MARTPGPALLCPGGGKAQLSSASPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCG--------------ALAG-SIIVEPHVTAVWGKNVSLKCLIEVN---ETITQISWEKIH-GKSTQTVAVHHPQYGFSVQ-GEYQGRILFKNY--------SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLMKGPDSLIDGG---NETVAAVCIAATGKPVARIDWEG---DLGEM-ESTITS-FPNETATIIS---QYKLFPTRFARGRRITCVVKHPALEK---DIRYSFILDIQYAPEVSVTGYDGN--WFVGRKGVNLKCNADANPPPFKSVWSRLDGEW----------PDGLL-ASDNTLHFVHPLTFNYS-GVYVCKVTNSLGQRSDQKVIYISDP--------------------------------------------------------------------------------------------------PTTTTLQPTVQWRSSTADVQDLATEHKKLPFPLS---------TLATLKDDTIGTIIASVVGGALFVVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSD-------MQKE----SQIDVLQHDEHDSYPDSVKKENKAPVNNLIRKDY------------------LEEPEKTQWNNVENLTR-FER------PMDYYEDLKMGMKFVSDE--RYNE---------------NEDDLVSHVDGSVISRREWYV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLB9-1", "uniprot_id": "NECT3_MOUSE", "id": "Q9JLB9-1", "name": "Nectin-3", "aln": "--MARTPGPAPLCPGGGKAQLSSAFPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCG--------------ALAG-SIIVEPHVTAVWGKNVSLKCLIEVN---ETITQISWEKIH-GKSTQTVAVHHPQYGFSVQ-GDYQGRVLFKNY--------SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG---NETVAAVCVAATGKPVAQIDWEG---DLGEM-ESSTTS-FPNETATIVS---QYKLFPTRFARGRRITCVVKHPALEK---DIRYSFILDIQYAPEVSVTGYDGN--WFVGRKGVNLKCNADANPPPFKSVWSRLDGQW----------PDGLL-ASDNTLHFVHPLTVNYS-GVYVCKVSNSLGQRSDQKVIYISDP--------------------------------------------------------------------------------------------------PTTTTLQPTVQWHSSPADVQDIATEHKKLPFPLS---------TLATLKDDTIGTIIASVVGGALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSD-------MQKE----SQIDVLHQDELDSYPDSVKKENKNPVNNLIRKDY------------------LEEPEKTQWNNVENLTR-FER------PMDYYEDLKMGMKFVSDE--RYNE---------------SEDGLVSHVDGSVISRREWYV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQS3-1", "uniprot_id": "NECT3_HUMAN", "id": "Q9NQS3-1", "name": "Nectin-3", "aln": "--MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCG--------------ALAG-PIIVEPHVTAVWGKNVSLKCLIEVN---ETITQISWEKIH-GKSSQTVAVHHPQYGFSVQ-GEYQGRVLFKNY--------SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGG---NETVAAICIAATGKPVAHIDWEG---DLGEM-ESTTTS-FPNETATIIS---QYKLFPTRFARGRRITCVVKHPALEK---DIRYSFILDIQYAPEVSVTGYDGN--WFVGRKGVNLKCNADANPPPFKSVWSRLDGQW----------PDGLL-ASDNTLHFVHPLTFNYS-GVYICKVTNSLGQRSDQKVIYISDP--------------------------------------------------------------------------------------------------PTTTTLQPTIQWHPSTADIEDLATEPKKLPFPLS---------TLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSD-------MQKE----SQIDVLQQDELDSYPDSVKKENKNPVNNLIRKDY------------------LEEPEKTQWNNVENLNR-FER------PMDYYEDLKMGMKFVSDE--HYDE---------------NEDDLVSHVDGSVISRREWYV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EG3-1", "uniprot_id": "NECT3_DANRE", "id": "Q58EG3-1", "name": "Nectin-3-like protein", "aln": "--MALTMTAHFLRN----------------------NPIQLGLNLRVLLMLSFVSG--------------LVYGSQVIVPPKVNAVLGKNVTLSCRVQVDT-NLSLTQSSWERKL-PNGWVTLAVYNPMFGISIP-PDYERRLSFRSP--------SALDATIMLEDVGFADIGVYTCKVATFPLGNTQASTTVSVLVEPKVYVSAGSSALIDGG---NETTVATCIAERARPPADVSWET---NLYGMSEAHMQE-DANGTTTTQV---HYIWQPSRHAQGHTLTCVVKHPALQS---DFRIPYIINVQFAPDILVLGYDGD--WYVGRENVQLKCRAKANPPAQHFRWIRLDGEM----------PNGAE-RVNNTLVFTRPLQKNDS-GVYRCEVANDIGLHSRDIRIRIQDP--------------------------------------------------------------------------------------------------PSTTTMPPTTPVRLLTADISATAPGNKQRALITSP--------TLAPLHEGSLGTIVGGAVGGALFLLLLLILAGVYYQRQRRTFRGDYYTKQYHGPSD-------MQKA----PQPHELQQVYSKGSPDTKLKSNQDNGTIYPDKDREEWGDFDRERSPNGRSRALREAGQLNHHNHQNHEHGFHSNHHTGHPQSYSPAHHIQRSSLQPQPRRYPAPQVMSNGSPYLPEDCYDNEYVSHTDGSMISRREWYV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZET1-1", "uniprot_id": "D3ZET1_RAT", "id": "D3ZET1-1", "name": "Nectin-4", "aln": "--------------------------------MPLSLGAEMWGPEAWLL-LLFLASFT-----------GRYSAGELETSDLVTVVLGQDAKLPCFYRGDP-DEQVGQVAWARVDPNEGTRELALLHSKYGLHVS-PAYEDRVEQPPP------PRDPLDGSILLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQG-----LTLAASCTAEGSPAPSVTWDT---EVKGTQSSRSFK-HSR-SAAVTS---EFHLVPSRSMNGQPLTCVVSHPGLLQ---DQRITHTLQVAFLAEASVRGLEDQNLWHVGREGATLKCLSEGQPP-PKYNWTRLDGPL----------PSGVR-VKGDTLGFP-PLTTEHS-GVYVCHVSNELSSRASQVTVEVLAD--------------------------------------------------------------------------------------------------PEDPGKQ----------------------------------------VDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYS-----------------TLTTVREIETQTELLSPGSGRTEEEDDQDEGIKQAMNHFVQEN---------------------GTLRAKPTGNGIYINGRGHLV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R007-1", "uniprot_id": "NECT4_MOUSE", "id": "Q8R007-1", "name": "Nectin-4", "aln": "--------------------------------MPLSLGAEMWGPEAWLR-LLFLASFT-----------GQYSAGELETSDVVTVVLGQDAKLPCFYRGDP-DEQVGQVAWARVDPNEGIRELALLHSKYGLHVN-PAYEDRVEQPPP------PRDPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQG-----LTLAASCTAEGSPAPSVTWDT---EVKGTQSSRSFT-HPR-SAAVTS---EFHLVPSRSMNGQPLTCVVSHPGLLQ---DRRITHTLQVAFLAEASVRGLEDQNLWQVGREGATLKCLSEGQPP-PKYNWTRLDGPL----------PSGVR-VKGDTLGFP-PLTTEHS-GVYVCHVSNELSSRDSQVTVEVLD---------------------------------------------------------------------------------------------------PEDPGKQ----------------------------------------VDLVSASVIIVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYS-----------------TLTTVREIETQTELLSPGSGRTEEDDDQDEGIKQAMNHFVQEN---------------------GTLRAKPTGNGIYINGRGHLV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NY8-1", "uniprot_id": "NECT4_HUMAN", "id": "Q96NY8-1", "name": "Nectin-4", "aln": "--------------------------------MPLSLGAEMWGPEAWLLLLLLLASFT-----------GRCPAGELETSDVVTVVLGQDAKLPCFYRGDS-GEQVGQVAWARVDAGEGAQELALLHSKYGLHVS-PAYEGRVEQPPP------PRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQG-----LTLAASCTAEGSPAPSVTWDT---EVKGTTSSRSFK-HSR-SAAVTS---EFHLVPSRSMNGQPLTCVVSHPGLLQ---DQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPP-PSYNWTRLDGPL----------PSGVR-VDGDTLGFP-PLTTEHS-GIYVCHVSNEFSSRDSQVTVDVLDP--------------------------------------------------------------------------------------------------QEDSGKQ----------------------------------------VDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYS-----------------TLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQEN---------------------GTLRAKPTGNGIYINGRGHLV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9R8-1", "uniprot_id": "A0AB13A9R8_DANRE", "id": "A0AB13A9R8-1", "name": "Nectin cell adhesion molecule 3", "aln": "------------------------------------MSDFTMINCCLVLAACLLSSQ-------------AVWSQRVRVEYEVTAYPNGSVNLRCEFTNSG-TTKLTQVSWMFERAENDRQNIAVFHPQYGASFPNKDFEGRVKFTQG--------SLENPSIRIDKLRMADAGRYICEYATYPSGNEQGTTTLIMLAKPKNS-ATAIPVRAGTS----EVVVATCAAAQGKPEATISWIT---TITGRYNHTSVP-ESDGTVTVKS---EYRMIPTPVENGKEITCVVNQRTQME---DKVFNLKLVVEYPPTVTIDGYDNN--WYMGRTDVYLTCEADANPEPSEISWTVATGQM----------PSSVR--VEENRLLVRKVDETVN-TTFVCEVKNRLGTGKKELVALVIES------------------------------------------------------------------------------------------------------------------------------------------------TEDPSSAGVVAGAILGSFLALVLVGALVTVLIMRSRRQQHGYSADGEQSVYGN--------------KTRLFGGKKSSKNGAGANNNGPIYTYRESDPGALTEKCNEFPHMTSSTPTAHDILLSGDLNEAERRKFEAMNDSLEDEEEDERYDRFSGLPPSYQIHRHEDECAP-------------YLDDDMESQRDGSIISRTAIYV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15151-1", "uniprot_id": "PVR_HUMAN", "id": "P15151-1", "name": "Poliovirus receptor", "aln": "--------------------------------MARAMAAAWPLLLVALLVLSWPPPG--------------TGDVVVQAPTQVPGFLGDSVTLPCYLQVPN--MEVTHVSQLTWARHGESGSMAVFHQTQGPSYS---ESKRLEFVAARLG----AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEP-----VPMARCVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTS---LWILVPSSQVDGKNVTCKVEHESFEK---PQLLTVNLTVYYPPEVSISGYDNN--WYLGQNEATLTCDARSNPEPTGYNWSTTMGPL----------PPFA--VAQGAQLLIRPVDKPIN-TTLICNVTNALGARQAELTVQVKEG---------------------------------------------------------------------------------------------------------------------------------------------PPSEHSGISRNAIIFLVLGILVFLILLGIGIYFYWSKCS----REVLWHCHLCPSS---------------TEHASASANGHVSYSAVSRENSSSQDPQTEGTR--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYH7-1", "uniprot_id": "A0AB32TYH7_DANRE", "id": "A0AB32TYH7-1", "name": "Nectin cell adhesion molecule 3", "aln": "----------------------MNGVSFNRLEQEMLYYHRWRSKTVILLFVYFLICVR--------------ISGEEVIGHDTAVEYGERANLLCHLTDTK--EDITLIMWKKTTKRKTEEDIFFVIHQDDKTEHINGLGDRVQFIGS-------FAERNGSIQLRGMEFLDEGTYTCIFNLFPSGPIATYIKASVFARPAVTVKGEEPVIGCLE-----VILASCFASNARPAAEVTWRLGELEKSLKTRTNHTV-NANETITVVS---YLLGVPFKHLHKKNIQCVVKHNSLTE---HLVLNYTIDIHYPPESVIIIPDSS----TDVNEFRCIVDSNPQPTLKGYNWTRVNKSS----------QFFE-----GNRLPVPNMTPELN-GLYICNASNKYGSALGSLYVNVHAG--------------------------------------------------------------------------------------------------DGFQYHR--------------------------------LTLKETRIQHSQETHQLICHLFRQMLHRNPTQRVHQVRALQKK---EGQLRFNYALNLKA-------------FVARGRKWIHLRYAPASDPTDGALDHKRRNEGRGSRER-------------------TGPGHILLLLSVLPSVCSELPSLLLINHFKTASVLRLLLPGG--------------------QRAVNFITALNRGGLRTDPLY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15278-1", "uniprot_id": "FAS3_DROME", "id": "P15278-1", "name": "Fasciclin-3", "aln": "------------------------------------MSRIVFICLAAILTDALTWAQ------------------VNVEPNTALLNEGDRTELLCRYGRSIN---YCRIEIPG------------EQKVLNLSPEWSKTPGFTYFGAG-------LTAGQCGVSIERVKASNNGQVKCSLGVEGEELSGTIDLVVALRPQQPIIELLSRPNREGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYG-LYLEHTAIVNITIRASPQPKIEWTIDGAIVGQGRTDGRYSAYEPQYLGNDEYNVTLAIAGLTLEDTTKIYNLRASNELGLTDYQVRISSSSK-----------------------------------------------------------------------------------------------------------------------------------------------PPSSSLDVAAIVGIVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDT---------ESADIKATSTATATTTMGGVGVSAEEEETVNEQESPQEQQQQQ----------------QKKAKRLPAFAAAILRRFNEKDSRKYKDNQESLNIVEGSVQEIP------------------ATNNAIDGNDNEPKAIVWQSTSPVWTFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * : . : . * . . * . : * * : : : . :* : . . . ", "identical_positions": 6, "similar_positions": 20, "identity": "0.78%" }, { "cls_id": "homologset.agr.FB:FBgn0000640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08699-1", "uniprot_id": "PGDH_RAT", "id": "O08699-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCC1-1", "uniprot_id": "PGDH_MOUSE", "id": "Q8VCC1-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-MHVNGKVALVTGAAQGIGKAFAEALLLHGAKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILESIEKEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKITASKGIHFQDYDISPLLVKAPLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15428-1", "uniprot_id": "PGDH_HUMAN", "id": "P15428-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54398-1", "uniprot_id": "FBP2_DROME", "id": "P54398-1", "name": "Fat body protein 2", "aln": "MFDWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMEN-VKMMKKLQAINPSVKVVFMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKDVETTMGMNLTGMIQSTMMAMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFSVYAAAMHGILGFTRSMGDKMIYQKTGVMFMAMCPGLTNSEMIMNLRDN----VTWHHSESMVEAIESAKRQMPEEAAMQMIHAMEMMK-NGSMWIVSMG-----QLKEVTPTMHWQM---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .** .: .*: .*** : *: :. *: : .:* *: *: . *.:*:* :: :: .:.::::*: : :*::*:::*. ** :*: * *: :**..:*..* :.: **.* : * **:::*:**: ** *.. .**.*: ***:***** . ::** : .:***:..: :: .:..: .:.: : :: * * :* :* **:: :: . * : * ", "identical_positions": 63, "similar_positions": 99, "identity": "23.33%" }, { "cls_id": "homologset.agr.FB:FBgn0000658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB25-1", "uniprot_id": "D4AB25_RAT", "id": "D4AB25-1", "name": "", "aln": "-----------------------------------------------------------------MGRKMRG-AAAAGLWLLALGSLLTLWGGLLPPRTELPASRPPEDRLPRHPIQSGGPAPEPRFPLPPP------------------------------LVWDARGGSLKTFRALLTLAAGADNPPGR-------HPDDRGRHVPSGLSWPAEHTAVHGG------VFWSRGLEEQVPRGFSEAQAAAWLEVARGARVVALDRGGCGRSSNRLARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWVQVQEELRTAHWTEGSVVSLTRWLPNLTDVVVPEPWRSED--------------------------GRLRPLRDAGG------------------ELTNLSQAELVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRVMHRATSNLHRGPG-GALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGQDAAARLLRLYSRHEPR--FPELAELADPHAQLLQRRLDFLAKHILHCKAKYGRRPGDLITLRGREGLGYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQB4-1", "uniprot_id": "FJX1_MOUSE", "id": "Q8BQB4-1", "name": "Four-jointed box protein 1", "aln": "-----------------------------------------------------------------MGRKMRGAAAAAGLWLLALSSLLTLWGGLLPPRTELPASRPPEDRLPPHPIQSGGPAPEPRFPLPPP------------------------------LVWDARGGSLKTFRALLTLAAGADNPPRR-------HQDDRGRHEPSGLSWPEERRAVHGG------VFWSRGLEEQVPRGFSEAQAAAWLEVARGARVVALDRGGCGRSSNRLARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWVQVQEELRTAHWTEGSVVSLTRWLPNLTDVVVPEPWRSED--------------------------GRLRPLRDAGG------------------ELTNLSQAELVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRVMHRATSNLHRGPG-GALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGQDAAARLLRLYSRHEPR--FPELAELSEPHAQLLQRRLDFLAKHILHCKAKYGRRPGDLITLRGREGLGYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VR8-1", "uniprot_id": "FJX1_HUMAN", "id": "Q86VR8-1", "name": "Four-jointed box protein 1", "aln": "-----------------------------------------------------------------MGRRMRGAAATAGLWLLALGSLLALWGGLLPPRTELPASRPPEDRLPRRPARSGGPAPAPRFPLPPP------------------------------LAWDARGGSLKTFRALLTLAAGADGPPRQ-------SRSEPRWHVSARQPRPEESAAVHGG------VFWSRGLEEQVPPGFSEAQAAAWLEAARGARMVALERGGCGRSSNRLARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWAQVQEELRAAHWTEGSVVSLTRWLPNLTDVVVPAPWRSED--------------------------GRLRPLRDAGG------------------ELANLSQAELVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRVMQRATSNLHRGPG-GALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGQDAAARLLRLYRRHEPR--FPELAALADPHAQLLQRRLDFLAKHILHCKAKYGRRSGT-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54360-1", "uniprot_id": "FOJO_DROME", "id": "P54360-1", "name": "Extracellular serine/threonine protein kinase four-jointed", "aln": "MYDIKRLEAGQQKLQQAQQPLGLDLSGQQQQLTCSVITAPEHRANPNPSSISQSNPSEATHMTLLTLRRRRSLQRRACLLSILAAFVFGMALGVVVPMFGLPRHQDSPPDLPEEQIQMVAVEPLSSYRVEFIKETDELSAEQVFRNAFHLEQDKDAPDSMVVKKLDTNDGSIKEFHVQRTASGRYRKGPERRLSKKMPERVQPQETSRSPTTSPTNPTSEHQAGFIEEDVYWGPTVEQALPKGFAAKDQVSWERFVGEQGRVVRLEQGCGRMQNRMVVFADGTRACARYRQNTDQIQGEIFSYYLGQLLNIS-NLAPSAATVVDTSTPNWAAALGDITQAQWKERRPVVLTRWLSDLEPAGIPQPFQPLERHLNKHDVWNLTRHMQSERQAQSQPHGLLKRLGAASSPGSAHQSNAIEETGTGTETANGALVQRLIELAQWSDLIVFDYLIANLDRVVNNLYNFQWNADIMAAPAHNLARQSASQLLVFLDNESGLLHGYRLLKKYEAYHSLLLDNLCVFRRPTIDALRRLR-AAGAGRRLRDLFERTTSAGVRDVLPSLPDKSVKILVERIDRVLGQVQKCQGS--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. * * : . :: : *:: * ** : . ** . : . * . : : *:..**:* *:. * :. * : : : . * : : * . *:*. :*: :* **: : .:* . . *. . **** .**:. ********.** *.:***** :****.:**.:. ::.* * : *:: .:*. . :: *:*.* * *****.:* . :* *::. : * *: * *.. . .*::*.**:***:**** **:**:*.**:.:**:. :* .: ** * .. *******:**:****: :: *:. **:.:****. * : .*: . .*. ** *: * . *. *.: .::* .*:* : :: :*:.. ", "identical_positions": 133, "similar_positions": 136, "identity": "21.98%" }, { "cls_id": "homologset.agr.FB:FBgn0000659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35583-1", "uniprot_id": "FOXA2_MOUSE", "id": "P35583-1", "name": "Hepatocyte nuclear factor 3-beta", "aln": "----------MLGAVKMEGHE---------------------------PSDWSSYYAE-PEGYSSV--SNMNAGLG-MNGMN-TYMSMSAAAMGGGSGNMSAGSMNMSSYVGAGMSP-SLAGMSPG-AGAMAGMSGSAGAAGVAGMGPHLSPS---LSPLGGQAAGAMGGLAPYAN-MN-SMSPM-YGQAGLSRAR-----DPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVP--RSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAASSGG--------KKTAPGSQASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRGGLSELKGAPASALSPPEPAPSPGQQQQA--AAHLLGPPHHPGLPPEA--HLKPEHHYAFN----HPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGGYGSPMPGSLAMGPVTNKAGLDASPLAADTSYYQGVYSRPIMNSS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32182-1", "uniprot_id": "FOXA2_RAT", "id": "P32182-1", "name": "Hepatocyte nuclear factor 3-beta", "aln": "----------MLGAVKMEGHE---------------------------PSDWSSYYAE-PEGYSSV--SNMNASLG-MNGMN-TYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSP-SLAGMSPG-AGAMAGMSGSAGAAGVAGMGPHLSPS---LSPLGGQAAGAMGGLAPYAN-MN-SMSPM-YGQAGLSRAR-----DPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFND-FLKVP--RAPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCENELALKEAAGAGSGGG--------KKTAPGTQASQVQLGEAAGSASETPAGTESPHSSASPCQEHKRGGLSELKGTPASALSPPEPAPSPGQQQQA--AAHLLGPPHHPGLPPEA--HLKPEHHYAFN----HPFSINNLMSSEQQHHHSHHHHQPHKMDLKTYEQVMHYPGGYGSPMPGSLAMGPVTNKAGLDASPLAADTSYYQGVYSRPIMNSS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y261-1", "uniprot_id": "FOXA2_HUMAN", "id": "Q9Y261-1", "name": "Hepatocyte nuclear factor 3-beta", "aln": "----------MLGAVKMEGHE---------------------------PSDWSSYYAE-PEGYSSV--SNMNAGLG-MNGMN-TYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSP-SLAGMSPG-AGAMAGMGGSAGAAGVAGMGPHLSPS---LSPLGGQAAGAMGGLAPYAN-MN-SMSPM-YGQAGLSRAR-----DPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVP--RSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSG---------KKAAAGAQASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQA--AAHLLGPPHHPGLPPEA--HLKPEHHYAFN----HPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPG-YGSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07342-1", "uniprot_id": "FOXA2_DANRE", "id": "Q07342-1", "name": "Forkhead box protein A2", "aln": "----------MLGAVKMEGHEH--------------------------AADWSTYYGE-PECYTSV--SNMNTGLG-MNSMN-TYMTMSG--MSSTANMTAANTMNMS-YVNTGMSP-SMTGMSPG-TGAMAGMG-----AGMTGMSAALSPT---MSPMAAQAP-SMNALTSYSN-MN-AMSPM-YGQSNINRSR-----DPKTYRRSYTHAKPPYSYISLITMAIQQSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVP--RSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCDKKLSKDPS----------------RKTSEG----------GSNSSSESCNGNESPHSNSS-SNELKR-SLSDMK--SGQGLSP-DHAASPTSQ-----AQHLLAQ-HHSVLAHEG--HLKPEHHYSFN----HPFSINNLMSSEQQHH---------KMDLKTYEQVMHYG--YGSPMAGTLSMGSMASKAGLDSP----DTSYYQGVYSRPILNSS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35582-1", "uniprot_id": "FOXA1_MOUSE", "id": "P35582-1", "name": "Hepatocyte nuclear factor 3-alpha", "aln": "----------MLGTVKMEGHE---------------------------SNDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMN-TYMTMNTMTTSGNMTPASFNMSYANTGLGAGLSPGAVAGMPGASAGAMNSMT----AAGVTAMGTALSPGG--MGSMGAQPATSMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVA--RSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGG----SGGGGSKGGPESRKDPSGPGNPSAESPLHRGVHGKASQLEGAPAPGPAASPQTLDHSGATATGGASELKSPASSSAPPISSGPGALASVPPSHPAHGLAPHESQLHLKGDPHYSFN----HPFSINNLMSSSEQQH---------KLDFKAYEQALQYSP-YGATLPASLPLGSASVATRSPIEPSALEPAYYQGVYSRPVLNTS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23512-1", "uniprot_id": "FOXA1_RAT", "id": "P23512-1", "name": "Hepatocyte nuclear factor 3-alpha", "aln": "----------MLGTVKMEGHE---------------------------SNDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMN-TYMTMNTMTTSGNMTPASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMT----AAGVTAMGAALSPGG--MGSMGAQPAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNACFVKVA--RSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGG----SGGGGSKGVPENRKDPSGPVNPSAESPIHRGVHGKASQLEGAPAPGPAASPQTLDHSGATATGGGSELKSPASSSAPPISSGPGGWICTPLSP--TWLAPHESQLHLKGAPHYSFN----HPFSINNLMSSSEQQH---------KLDFKAYEQALQYSP-YGATLPASLPLGGASVATRSPIEPSALEPAYYQGVYSRPVLNTS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55317-1", "uniprot_id": "FOXA1_HUMAN", "id": "P55317-1", "name": "Hepatocyte nuclear factor 3-alpha", "aln": "----------MLGTVKMEGHE---------------------------TSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMN-TYMTMNTMTTSGNMTPASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMT----AAGVTAMGTALSPSG--MGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVA--RSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELKTPASSTAPPISSGPGALASVPASHPAHGLAPHESQLHLKGDPHYSFN----HPFSINNLMSSSEQQH---------KLDFKAYEQALQYSP-YGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35584-1", "uniprot_id": "FOXA3_MOUSE", "id": "P35584-1", "name": "Hepatocyte nuclear factor 3-gamma", "aln": "----------MLGSVKMEAHD---------------------------LAEWS-YYPEAGEVYSPV------NPVPTMAPLN-SYMTLNPLSSPYPPG-------------GLQASPLPTGPLAPP--------------APTAPLGPTFPSLG--TGGSTGGSASGYVAPG-----------------PGLVHGK----EMAKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVA--RSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNS---------------------------ATSASRNGTAGSATSATTTAATAVTSPAQPQPTP-SEPEAQSGDDVGGLDCASPPSST------------PYFSGLELPG--ELKLDAPYNFN----HPFSINNLMSEQ-------------------------------TSTPSKLDVGFGGYGAESGEP-----GVYYQSLYSRSLLNAS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32183-1", "uniprot_id": "FOXA3_RAT", "id": "P32183-1", "name": "Hepatocyte nuclear factor 3-gamma", "aln": "----------MLGSVKMEAHD---------------------------LAEWS-YYPEAGEVYSPV------NPVPTMAPLN-SYMSLNPLSSPYPPG-------------GLQASPLPTGPLAPP--------------APTAPLGPTFPGLG--AGSGTGGSASGYGAPG-----------------PGLVHGK----EMAKGYRRPLTHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVA--RSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNS---------------------------ATSATRNGTVGSATSATTTAATAVTSPAQPQPTPPSEPEAQSGEDVGGLDCASPPSSA------------PYFTGLELPG--ELKLDAPYNFN----HPFSINNLMSEQ-------------------------------TSTPSKLDVGFGGYGAESGEP-----GVYYQSLYSRSLLNAS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55318-1", "uniprot_id": "FOXA3_HUMAN", "id": "P55318-1", "name": "Hepatocyte nuclear factor 3-gamma", "aln": "----------MLGSVKMEAHD---------------------------LAEWS-YYPEAGEVYSPV------TPVPTMAPLN-SYMTLNPLSSPYPPG-------------GLPASPLPSGPLAPP--------------APAAPLGPTFPGLG--VSG--GSSSSGYGAPG-----------------PGLVHGK----EMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVA--RSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSG--------------------------AATTTRNGTGSAAS--TTTPAATVTSPPQP-PPPAPEPEAQGGEDVGALDCGSPASST------------PYFTGLELPG--ELKLDAPYNFN----HPFSINNLMSEQ-------------------------------TPAPPKLDVGFGGYGAEGGEP-----GVYYQGLYSRSLLNAS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14734-1", "uniprot_id": "FKH_DROME", "id": "P14734-1", "name": "Protein fork head", "aln": "MQKLYAEPPPSSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGG-CMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSR---VDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIP--RTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHK------------------SPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDYHSSMHPLKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQYAGYNALSPLTNSHAALGQDSYYQSLGYHAPAGTTSL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "----------MSVTSREQKFSG-------------------------KYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIG---GVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVP-------------HIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . .. . . : . .: . :. : : . . . : : *:: .: *::: : : ::: :: : . . .. ..* .: . ...: : .* . . :: . . .:: : . * .: .. . : ", "identical_positions": 5, "similar_positions": 70, "identity": "0.93%" }, { "cls_id": "homologset.agr.FB:FBgn0000662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5XW36-1", "uniprot_id": "A0A8I5XW36_RAT", "id": "A0A8I5XW36-1", "name": "Pre-mRNA-splicing regulator WTAP", "aln": "--------------------------------------------------------MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNS-------NDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ----------QQQ--SQASAPS-TSRTTSSEPVDQAE---ATS----KDCSRLANGP-----------SNGSSSRQRTSGSGFHREGSTPEDDFPSSS--------GNGNKASNSSEERTGRG-SSYIN------------PLSAGYESVDSPTGSENSLTHHSNDTDSSHDPQEEKAVSGKGNRTVGSRH-VQNGLDSSVN---------VQGSIL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER69-1", "uniprot_id": "FL2D_MOUSE", "id": "Q9ER69-1", "name": "Pre-mRNA-splicing regulator WTAP", "aln": "--------------------------------------------------------MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNS-------NDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ----------QQQ--SQASAPS-TSRTTSSEPVDQAE---VTS----KDCSRLANGP-----------SNGSSSRQRTSGSGFHREGSTPEDDFPSSS--------GNGNKASNSSEERTGRGGSSYIN------------PLSAGYESVDSPTGSENSLTHHSNDTDSSHDPQEEKAVSGKGNRTVGSRH-VQNGLDSSVN---------VQGAVL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15007-1", "uniprot_id": "FL2D_HUMAN", "id": "Q15007-1", "name": "Pre-mRNA-splicing regulator WTAP", "aln": "--------------------------------------------------------MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNS-------NDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ----------QQQ--SQASAPS-TSRTTASEPVEQSE---ATS----KDCSRLTNGP-----------SNGSSSRQRTSGSGFHREGNTTEDDFPSSP--------GNGNKSSNSSEERTGRGGSGYVN------------QLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQEEKAVSGKGNRTVGSRH-VQNGLDSSVN---------VQGSVL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXL7-1", "uniprot_id": "FL2D_DANRE", "id": "Q7SXL7-1", "name": "Pre-mRNA-splicing regulator WTAP", "aln": "--------------------------------------------------------MTNEEPLPKKVRLSESDMKTLTREELCTRWKQHETYVQMLEAKYADLNS-------NDVTGLKESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSAAQLRSSMVDPAINLFFLKMKAELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLRETRQQLSQMN----------QTQGTSSGAGPSRTSPSTASEPSTQSEPANASSSNVGKDCGRVSNGP-----------SNGNSSQRGASGSSLYREASSADEDYPPSPSVSSPTHDGISKLSNHSEDAVSQRGGEGYVT------------QLSAGYESVDSPTGSETSVTQHSNDTDSNADSHEAAAVP-KGSRTAGTRHSTQNGLDSSAAAVATNTSNASAGSVL--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y091-1", "uniprot_id": "FL2D_DROME", "id": "Q9Y091-1", "name": "Pre-mRNA-splicing regulator female-lethal(2)D", "aln": "MSVAAMTMDDQRPCMNSYDKMPPTKYEQNLNILNSSQNSGATGGPASPTPSGLEDHHHHHHPHPHHHHHQEQQQQQQQQQHLQQQQQQQQQQHAAAVAEAVAAAEQRQRLLEDEIENLKLEQVRMAQQCADAQRREKILMRRLANKEQEFQDYVSQIAEYKAQQAPTALALRTALLDPAVNLLFERLKKELKATKAKLEETQNELSAWKFTPDSNTGKRLMAKCRLLYQENEELGKMTSNGRLAKLETELAMQKSFSEEVKKSQSELDDFLQELDEDVEGMQSTILFLQQELKTTRDRIQTLEKENAQLKQAIKDEVVAPAAATNGGTNTTINKLETIHEDACMANNPTNPDCYNGNTNNEQIAAVPQIPLSDDGSNMNGNAARLARKRNYQEEEALPTVVVVPTPTPVGNNVQEAPPIREVTAPRTLPPKKSKLRGITTRRNSQLEEDHQPVTTPVAVPMIVDNAVAGMASEEAAAAAAAVNNSNTGIIPETG-VQVGVPVEGGDPG---APAAPGRILTRRRSVRMQQNGSGAVDYST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* *:: : .* : : ::.* : :* : .: . . ::: .*: .: :: ** :: ***:**: ***.****:*: .:** * * *:. **::::***:**:* ::* **: ** ***::*************:***:******:* ***:***: *:**:*:**:***:**.:***:*.**.**:**: :***:*********.***:*: **::: : : : : .:... : :* .: * :. ** . .. *:..*. . :. :. :: *. * . . : . *. .::.* :*.. : : . *. . ** ... .* *: . * :* ", "identical_positions": 128, "similar_positions": 129, "identity": "23.7%" }, { "cls_id": "homologset.agr.FB:FBgn0000667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4I6-1", "uniprot_id": "Q8R4I6_RAT", "id": "Q8R4I6-1", "name": "", "aln": "-------------------------------------------------------------------------MMMVMQPEGLGAGEGPFSG------GGGG-EYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQEGLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLG---------------------------EVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGSGAPSGALDYVAFSSALYGESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88990-1", "uniprot_id": "ACTN3_MOUSE", "id": "O88990-1", "name": "Alpha-actinin-3", "aln": "-------------------------------------------------------------------------MMMVMQPEGLGAGEGPFSG------GGGG-EYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLG---------------------------EVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGSGAPSGALDYVAFSSALYGESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08043-1", "uniprot_id": "ACTN3_HUMAN", "id": "Q08043-1", "name": "Alpha-actinin-3", "aln": "-------------------------------------------------------------------------MMMVMQPEGLGAGEGRFAG------GGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRIQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFRQKASLHEAWTRGKEEMLSQRDYDSALLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDRLQLEFARRAAPFNNWLDGAVEDLQDVWLVHSVEETQSLLTAHDQFKATLPEADRERGAIMGIQGEIQKICQTYGLRPCSTNPYITLSPQDINTKWDMVRKLVPSCDQTLQEELARQQVNERLRRQFAAQANAIGPWIQAKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKTNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKQNGMMEPDDFRACLISMGYDLG---------------------------EVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTTEQVVASFKILAGDKNYITPEELRRELPAKQAEYCIRRMVPYKGSGAPAGALDYVAFSSALYGESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ARF4-1", "uniprot_id": "A0A8I6ARF4_RAT", "id": "A0A8I6ARF4-1", "name": "F-actin cross-linking protein", "aln": "MSSVCCVLVLRPRLCAQACSPRNREKVTTARRLSIHPSIHPSIHPSIHPSIHFSIRLSIPRAALAPQSPQPPSAMNQIEPG------VQYNY------VYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLG---------------------------EAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPPYSGPGSVPGALDYTAFSSALYGESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI91-1", "uniprot_id": "ACTN2_MOUSE", "id": "Q9JI91-1", "name": "Alpha-actinin-2", "aln": "--------------------------------------------------------------------------MNQIEPG------VQYNY------VYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLG---------------------------EAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPPYSGPGSVPGALDYTAFSSALYGESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35609-1", "uniprot_id": "ACTN2_HUMAN", "id": "P35609-1", "name": "Alpha-actinin-2", "aln": "--------------------------------------------------------------------------MNQIEPG------VQYNY------VYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERMEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLG---------------------------EAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPAYSGPGSVPGALDYAAFSSALYGESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N882-1", "uniprot_id": "A0A8M1N882_DANRE", "id": "A0A8M1N882-1", "name": "", "aln": "-------------------------------------------------------------------------MMNQIELS------VPYDN------GYEIDEYMMQEDEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDFITSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHVSWKDGLALCALIHRHRPDLIDYAKLNKDDPLGNLNLAFDIAEKHLDIPKMLDAEDILSTPKPDERAIMTYVSCFYHAFAGAEQA----------------------ETAANRICKVLGVNQENEKLMEDYERLASELLEWIRRTIPWLENRAAEKTMVEMQRKLEDFRDYRRMHKPPKVQEKCQLEISFNTLQTKLRISNRPAFMPSEGKMVSDIASAWQGLEQAEKGYEEWLLTEIRRLERVEHLAEKFRQKATNHESWATGKEEMLTRKDYESASLMEVRALLRKHEAFESDLSAHQDRVEQIAAIAQELNELDYHDVASVNQRCQSICDLWDHLGTLTQKRREALERTEKLLETVDQLFLEYAKRSAPFNNWMEGAMEDLQDMFIVHTIEEVQTLIAAHEQFKATLPEADAERQAILGIQQEVLKIFQSYGIRGDLTNPYSTITAEEIAIKWDKVKKLVPQRDSALQEELARQHANERLRRQFAAQANLIGPWIQTRMEEIGHCSMAMGGTLEDQMTQLKQYEHVIVSYKSNIDRLEGDHQLIQESLIFDNKHTNYTMEHVRVGWELLLTTIARTINEIETQILTRDAKGISQEQMHEFRSSFNHFDRKKNGGMDSDDFRACLISMGYDLG---------------------------EVEFARIMMLVDPNASGNVSFQSFIDFMTRETADTDTAEQVIASFKILAADKPYILSDELRRELPPDQAEYCISRMPPYCGPGALPGALDYTAFSTALYGESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z1P2-1", "uniprot_id": "ACTN1_RAT", "id": "Q9Z1P2-1", "name": "Alpha-actinin-1", "aln": "--------------------------------------------------------------------------MDHYDSQQ-------------------TNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMQAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHSRQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQ----------------------GEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITGDELRRELPPDQAEYCIARMAPYAGPDSVPGALDYMSFSTALYGESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPR4-1", "uniprot_id": "ACTN1_MOUSE", "id": "Q7TPR4-1", "name": "Alpha-actinin-1", "aln": "--------------------------------------------------------------------------MDHYDSQQ-------------------TNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLECDHQLIQEALIFDNKHTNYNMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQ----------------------GEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITEDELRRELPPDQAEYCIARMAPYAGPDSVPGALDYMSFSTALYGESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12814-1", "uniprot_id": "ACTN1_HUMAN", "id": "P12814-1", "name": "Alpha-actinin-1", "aln": "--------------------------------------------------------------------------MDHYDSQQ-------------------TNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQ----------------------GEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T375-1", "uniprot_id": "A0AB32T375_DANRE", "id": "A0AB32T375-1", "name": "", "aln": "--------------------------------------------------------------------------MDHHHHPQHHHHHQYDGG---------ENDYMQQEDDWDRDMLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALGFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYNKLRKDDPMTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMQAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDISNSWGRLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEAWTDGKEEMLQHKDFETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELEYYDSPSVNARCQRICDQWDSLGVLTQKRSEALQRTEKLLETIDQLYLEFAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLSTAHEQFKATLPEADKERQAILGIHNEIAKIVQTYHVNMAGQNPYTTINPQEINAKWDKVRQLVPQRDQALIEEHARQQNNERLRRQFANQANVIGPWIQTKMEEIGRISIEMHGTLEDQLTHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEIENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGAEEFKACLISLGFDIGNDAQKRTGMMDAEDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKVLAGDKNYILADELRRELPPDQAEYCIARMTPYSGPDSVPGALDYMSFSTALYGESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QXQ0-1", "uniprot_id": "ACTN4_RAT", "id": "Q9QXQ0-1", "name": "Alpha-actinin-4", "aln": "-------------------------------------------------------------------------MVDYHAANQAYQYGPSSGG-NGTGGGGGMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEKQLETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTSVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHLRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQ----------------------GDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAAPGALDYKSFSTALYGESDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57780-1", "uniprot_id": "ACTN4_MOUSE", "id": "P57780-1", "name": "Alpha-actinin-4", "aln": "-------------------------------------------------------------------------MVDYHAANQAYQYGPNSGGGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKQRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEKQLETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPSLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQ----------------------GDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAAPGALDYKSFSTALYGESDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43707-1", "uniprot_id": "ACTN4_HUMAN", "id": "O43707-1", "name": "Alpha-actinin-4", "aln": "-------------------------------------------------------------------------MVDYHAANQSYQYGPSSAG-NGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQ----------------------GEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QL95-1", "uniprot_id": "A0A8M9QL95_DANRE", "id": "A0A8M9QL95-1", "name": "", "aln": "-------------------------------------------------------------------------MVDYHAVNNQGQYS-----------AGGPPTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIDYDKLRKDDPVTNLNNAFEVAERYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKA----------------------ETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLENRAPEKTMAEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINGAWHKLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEGWTDGKEAMLTQKDYETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICEQWDALGSLTQNRRESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIDEIQGLITAHEQFKSTLPEANKEREAIQAIQAEVQKIANYNGIKLAGNNPYTTITPQSIDKKWEKVQQLVPQRDQALQEELTRQQSNDHLRRQFANQANMIGPWIQNKMEEIGRISIEMNGTLEDQLTHLSQYEQSIIEYKPNIDQLEGDHQLIQEALIFDNKYTAYTMEHLRVGWEQLLTTIARTINEIENQVLTRDAKGISQEQLHEYRTSFNHFDKDHSGLLQSEEFKACLISLGYDVENDKQKRTGIMDSDDFRALLISTGNSLGDAEFARIMGIVDPNNSGAVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNYITAEELRRELPPDQAEYCIARMAPYSGPDAVAGALDYMSFSTALYGESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18091-3", "uniprot_id": "ACTN_DROME", "id": "P18091-3", "name": "Alpha-actinin, sarcomeric", "aln": "-------------------------------------------------------------------------MMMENGLSMEYG-----------------DGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPEPTRQYTYVPNNYNAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQ----------------------GDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGALDYMSFSTALYGETDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** *::*:*: **********:**************** *:**:****:************** *.:*::****.*** ******.:*:****:************* *********************** :****************:***:**** *:****.: ********:**:* ** **:*: *:* *:::**:.****:***.:*::.*.:***:*******.:**** **::. *********** ******:***:**:***:********:***:.* : :: :*:***::* *** ****::::*.:** .*********:*:***::*:**: **** ..* ** .**.:*:*** * **:*::***:**::** ** *: *** :* :*: . * :::** ::********:*******:***:***** *:*:: .** *** **: ** ** **: * :*:. *: ** :* * **:*:*:******::.: *** * ::**.::* : * **:***:** :*: * * : * : : : *** ::. : : **. *::*** * :* :* :*: *: **:**. :** :****: ::: : . : *:**:*: * : *: : ** .:: ** ** :**.::*:*::* *.** :***** ***:* *.***:*.*:****:**::***::*:*:******: : * : ::*::**:*:*:.: : :* **: :**** * * *::*:***:**:::***::**: **::**.** :* :*******..**:*** ** .* *... .***** :**:*****:**", "identical_positions": 499, "similar_positions": 228, "identity": "48.49%" }, { "cls_id": "homologset.agr.FB:FBgn0000709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F0E5-1", "uniprot_id": "F7F0E5_RAT", "id": "F7F0E5-1", "name": "Protein flightless-1 homolog", "aln": "MEATGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLHLRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPNLHRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMAANNNLELIPESLCRCPKLRKLVLNKNRLVTLPEAIHFLTEIEVLDVRENPSLVMPPKPADH----TAEWYNIDFSLQNQLRLAGASPATVAAAAAVGSGSKDPLARKMRLRRRKDSAQDVQAKQVLKGMSDVAQEK-NKNQEESTDARAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTAREEMGDESEGFLQVFDNDISYIEGG-TASGFYTVEDTHYVTRMYRVYGK-KNIKLEPVPLKGTSLDPRFVFLLDQGLDIYVWRGAQATLSNTTKARLFAEKMNKNERKGKAEITLLVQGQEPPEFWDVLGGEPSE------IKKHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPGMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHTVVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQGPGISGKVKRDTEKKDQMKADLTALFLPRQPPMPLAEAEQLMEEWNEDLDGMEGFVLEGRKFTRLAEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKPEDKEGKASAEGREEEEAAAETEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKVTQ-TLQPT----LYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQ--GIVYAWVGRASDPDEAKLAEDILNTMFDPSYS-KQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHTRSKEHERPRRLRLVRKGNEQRAFTRCFHAWSTFRQAPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ28-1", "uniprot_id": "FLII_MOUSE", "id": "Q9JJ28-1", "name": "Protein flightless-1 homolog", "aln": "MEATGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLHLRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMAANNNLELIPESLCRCPKLKKLVLNKNRLVTLPEAIHFLTEIQVLDVRENPSLVMPPKPADR----TAEWYNIDFSLQNQLRLAGASPATVAAAAAVGSGSKDPLARKMRLRRRKDSAQDVQAKQVLKGMSDVAQEK-NKNQEESIDARAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGG-TASGFYTVEDTHYVTRMYRVYGK-KNIKLEPVPLKGSSLDPRFVFLLDQGLDIYVWRGAQATLSNTTKARLFAEKINKNERKGKAEITLLVQGQEPPGFWDVLGGEPSE------IKNHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPGMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHTVVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQGQGLSGKVKRDTEKTDQMKADLTALFLPRQPPMPLAEAEQLMEEWNEDLDGMEGFVLEGRKFTRLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKTEDKEGKASAEAREGEEAAAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKVTQGTLQPT----LYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQ--GIVYAWVGRASDPDEAKLAEDILNTMFDASYS-KQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHTRSKEHERPRRLRLVRKGNEQRAFTRCFHAWSTFRQAPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13045-1", "uniprot_id": "FLII_HUMAN", "id": "Q13045-1", "name": "Protein flightless-1 homolog", "aln": "MEATGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMPPKPADR----AAEWYNIDFSLQNQLRLAGASPATVAAAAAAGSGPKDPMARKMRLRRRKDSAQDDQAKQVLKGMSDVAQEK-NKKQEESADARAPSGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGG-TASGFYTVEDTHYVTRMYRVYGK-KNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLLVQGQELPEFWEALGGEPSE------IKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQSPGLSGKVKRDAEKKDQMKADLTALFLPRQPPMSLAEAEQLMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKKEDKE--EKAEGKEGEEATAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAVQGAQQPS----LYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQ--GIVYAWVGRASDPDEAKLAEDILNTMFDTSYS-KQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAWSAFCKALA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8WK50-1", "uniprot_id": "FLII_DANRE", "id": "F8WK50-1", "name": "Protein flightless-1 homolog", "aln": "MAATGVLPFIRGVDLSGNDFKGGNFPEHVKSMTSLRWLKLNRTGLCYLPEELASLQKLEHLSVSHNSLTTLHGELSSLPNLRAVVARANNLKNSGVPDDIFQLDDLSVLDLSHNQLTEIPRDLENSRNMLVLNLSHNSIDNIPNQLFINLTDLLYLDLSDNNLDSLPPQMRRLVHLQTLILNNNPLMHAQLRQLPVMVSLQTLHLRNTQRTQNNMPTSLEGLSNLTDVDLSCNDLTRVPECLYSLVNLKRLNLSSNQISELSLCIDQWTKLETLNLSRNQLTSLPSAICKLSKLKKLYVNSNKIDFDGLPSGVGKLSNLVEFMAANNNLELVPEGLCRCGKLKKLVLNKNRLVTLPEAIHFLTELEVLDVRENPNLVMPPKPVDR----TAEWYNIDFSLQNQLRLAGASPATVAAAGGGNS-PRDHMARKMRLRRCKDSAHDDQAKQVLKGMSDVAQEK-NKSIEENGDLKYSDLKTKRWDKNLEKPQLDYSEFFLEDVGQIPGVSVWQIENFIPIQVDEAFHGKFYEADCYIILKTFLDENGALNWQIFYWIGQDATLDKKAGAAIHAVNLRNYLGAECRTIREEMGDESEEFTVVFDHEISYIEGG-TASGFYTVEDTQYPTRLYRVYGK-KNIRLESVPLKASSLDPQFVFLLDTGLEIYVWRGGNATLGGTTKARLFAEKINKNERKSKAEITTLMQNQEPPEFWEVLGGQPEE------IKKHVPDDFTPIRPKLYKVGLGLGYLELPQINYKLSVEHKDKLKLDVVPELRLVQGLLDTKGVYILDCWSDVFIWIGRKSPRLVRAAALKLGQEVCGMLHRPKHAVVIRNLEGTECQVFKSKFKNWDDVLKVDYTRNAESVKQEAGLSGKVKKDVEQKDQMKADLTALFLPRQPAMPLTEAEQMMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFHTQDCYVFLCRYWVPVEYEDDKEK------GKEKGEEGD-----DEEKQPEEDFQCVVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENLKFLSHFKRKFIIHKGKRKLKVDSVQPS----LYHIRTNGSALCTRTIQIATDSSNLNSEFCFILKVPFESTDNQ--GIVYTWVGRAADPDEAKLAEEIMNTMFDDTYS-KQVINEGEEPENFFWVGIGSQKTYDEDAEYMKYARLFRCSNEKGYFAVSEKCSDFCQDDLADDDIMLLDNGKEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKDTENPRKLRLVRKGNEPHCFTRCFHAWSAFKTAPA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24020-1", "uniprot_id": "FLII_DROME", "id": "Q24020-1", "name": "Protein flightless-1", "aln": "---MSVLPFVRGVDFTKNDFS-ATFPSSMRQMSRVQWLTLDRTQLAEIPEELGHLQKLEHLSLNHNRLEKIFGELTELSCLRSLDLRHNQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNLSNNQIESIPTPLFIHLTDLLFLDLSHNRLETLPPQTRRLINLKTLDLSHNPLELFQLRQLPSLQSLEVLKMSGTQRTLLNFPTSIDSLANLCELDLSHNSLPKLPDCVYNVVTLVRLNLSDNELTELTAGVELWQRLESLNLSRNQLVALPAALCKLPKLRRLLVNDNKLNFEGIPSGIGKLGALEVFSAANNLLEMVPEGLCRCGALKQLNLSCNRLITLPDAIHLLEGLDQLDLRNNPELVMPPKPSEASKATSLEFYNIDFSLQTQLRLAG---AAVPPSMPSSATPKDSTARKIRLRRGPRSEGDQDAAKVLKGMKDVAKDKDNEAGAVPEDGKPESLKPKRWDESLEKPQLDYSKFFEKDDGQLPGLTIWEIENFLPNKIEEVVHGKFYEGDCYIVLKTKFDDLGLLDWEIFFWIGNEATLDKRACAAIHAVNLRNFLGARCRTVREEQGDESEQFLSLFETEVIYIEGGRTATGFYTIEEMIHITRLYLVHAYGATIHLEPVAPAITSLDPRHAFVLDLGTHIYIWMGERSKNTLNSKARLMAEKISKTERKNKCEIQLERQGEESAEFWQGLGMTSEEADAAEPPKEHVPEDYQPVQPRLYQVQLGMGYLELPQV---------------ELPEQKLCHTLLNSKHVYILDCYTDLFVWFGKKSTRLVRAAAVKLSRELFNMMDRPDYALVMRVPEGNEMQIFRTKFAGWDEVMAVDFTRTAKSVAK----TGANLTQWARQQETRTDLAALFMPRQSAMPLAEAEQLEEEWNYDLEMMEAFVLENKKFVRLPEEELGRFYTGECYVFLCRYCIPIEEPENGSE--------DGANPAADVSKSSANNQPEDEIQCVVYFWQGRNAGNMGWLTFTFTLQKKFKAMFGEELEVVRIFQQQENLKFMSHFKRKFIIHTGKRKDKAHTAKGKSPVEFFHLRSNGGALTTRLIQINPDAVHLNSTFCYILHVPFETEDDSQSGIVYVWIGSKACNEEAKLVQDIAEQMFNSPWVSLQILNEGDEPENFFWVALGGRKPYDTDAEYMNYTRLFRCSNERGYYTVAEKCADFCQDDLADDDIMILDNGEHVFLWMGPRCSEVEVKLAYKSAQVYIQHMRIKQPERPRKLFLTMKNKESRRFTKCFHGWSAFKVYL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****:****:: ***. . **. :: *: ::**.*:** *. :****. ********:.** * .:.***:.*. **:: * *.*****:* ::*:*::*:.******:*.* *. **.::*::*****:* *:.**. ***:*****:****.*.*::**** ***::*:** *. *** ****** : :*:.*:: .**** *:***::.*:** ::*** *.*.::*:*:*.: .* *****.*:::**: :: * ::*:********.:**:*:***.**::* :*.**::*:*:***:*** * * **** **::**.**** *::* *. *:*:***:***:* :: **:*:**.******* : : *:********.****** *:*..: .: .:* ***:**** * * :* :*****.***::* *: * : . * :***:.****:****:** :* **:**:::*:****:* ::*..******.****:*** :*: * *:*:*::*** :*****:* :*********:***.*** *** ***** * :*: :: ***** **:****:*: : **:* *:. .*:**.*. :****:..*:** * .**:* * .:. .:****:***:.*.***.*.** *.:* . **: ** ..* *:***:*: * :*:**:* **:*******: :* :* : **::: ******::*:*:*:*:**.*******:**.:*: .*:.** :: * * **.* *:*::** .**:*: **:**.*::* : :* : : :: ::**:***:***..*.*:****: **** **: **.****.:**.**.***:*:*:* :******** :*:* :: . .. ::***:::**:*******:*.*********:*****:::* :*****: ***** **:********** **** : : . ::::*:**.** ** *** .*: *** **:**:****: *:. ****.*:* : :****.::* : **: .: *::***:********.:*.:*.** *****:::********:**::*:***:*************:****:.*::*:*.: *:**:**: *:.****** * *: *.**:* *. *.:* : **:***.**:* ", "identical_positions": 662, "similar_positions": 363, "identity": "51.28%" }, { "cls_id": "homologset.agr.FB:FBgn0000711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62140-1", "uniprot_id": "PP1B_HUMAN", "id": "P62140-1", "name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "aln": "MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTA---NPPKKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62141-1", "uniprot_id": "PP1B_MOUSE", "id": "P62141-1", "name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "aln": "MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTA---NPPKKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62142-1", "uniprot_id": "PP1B_RAT", "id": "P62142-1", "name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "aln": "MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTA---NPPKKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N207-1", "uniprot_id": "A0A8M1N207_DANRE", "id": "A0A8M1N207-1", "name": "Serine/threonine-protein phosphatase", "aln": "MAEGELNVDSLISRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDESLMCSFQILKPSEKKAKYQYSGVNSGRPVTPPRTA---QAPKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48462-1", "uniprot_id": "PP1B_DROME", "id": "P48462-1", "name": "Serine/threonine-protein phosphatase beta isoform", "aln": "MGDFDLNVDSLIQRLLEMRSCRTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAKYLYSGMNSSRPTTPQRSAPMLATNKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32598-1", "uniprot_id": "PP12_YEAST", "id": "P32598-1", "name": "Serine/threonine-protein phosphatase PP1-2", "aln": "MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSLPRQAGGR------------------KKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ::**.:* ****:*..:.*: *:: * *:* ** *:*.**:.**********: ********* ************* :**********************************:***********************:*:**************:***:****** ********:.******:*****:**.**************: **.*********** ***.:**::::::****************::********************.**:**::*:********::*. .* **:", "identical_positions": 239, "similar_positions": 52, "identity": "72.42%" }, { "cls_id": "homologset.agr.FB:FBgn0000721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8L4-1", "uniprot_id": "A0ABK0M8L4_RAT", "id": "A0ABK0M8L4-1", "name": "cGMP-dependent protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELEEDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPV--------------------------PSTHIGPR--------TTRAQGISAEPQTYRSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPDEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVI--AAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C605-1", "uniprot_id": "KGP1_MOUSE", "id": "P0C605-1", "name": "cGMP-dependent protein kinase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELEEDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPV--------------------------PSTHIGPR--------TTRAQGISAEPQTYRSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPDEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGQVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVI--AAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13976-1", "uniprot_id": "KGP1_HUMAN", "id": "Q13976-1", "name": "cGMP-dependent protein kinase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELEEDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPV--------------------------PSTHIGPR--------TTRAQGISAEPQTYRSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVI--AAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H0N0-1", "uniprot_id": "A0AC58H0N0_DANRE", "id": "A0AC58H0N0-1", "name": "cGMP-dependent protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVYVFLDTAHRDVWNRSDRQRERRRIPVSTVNTMSDLDEDFAKILMLKEERIRDLERRLLEREDEISELKRKLHKCQSVL----------------------------PSAQIGPR--------THRAQGISAEPQTHQDLS--NQSFRRVAKSDRSKDLIKSAILDNDFMKNLEMSQIQEIVDCMYPVDYDKNSCIIKEGDVGSLVYVMEDGKVEVTKEGLKLCTMGPGKVFGELAILYNCTRTATVRTVSSVKLWAIDRQCFQTIMMRTGLIKHAEYMELLKSVLTFRGLPEEILSKLADVLEETHYEDGNYIIRQGARGDTFFIISKGKVTMTREDCPGQEPVYLRSMGRGDSFGEKALQGEDIRTANVI--AAETVTCLVIDRDSYKHLIGGLEDVSNKGCEDAEAKAKYEAENAFFSNLNLSDFNIIDTLGVGGFGRVELVQLKSDEMKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGNFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDTPSERLGNLKNGVKDIQKHKWFEGFNWDGLRKGTLMPPIIPNVTSSTDTSNFDSFPEDNEDPPPDDNSGWDIDF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03043-1", "uniprot_id": "KGP24_DROME", "id": "Q03043-1", "name": "cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B", "aln": "MRFCFDRLCFATKRPAQNSNSNAPHSSTTVDAPPRPADVDVATVPVATPAPPPQQPVSNLFYADYQKLQPAIIDRDWERDRDTDTDTRSEAKPPDIVEHIEPVEEQRQIHTQIQSPAEIQIQIPPTPPAPSIQIQIQQRYRRHSSAEDRNLNTRRNDSNITEALRKAASMQQEPNANYQFPTDLGLVSIVNNNNNTNTHPSGSNSGSNNNSNINNNLVGGIVTLPAAGGLIGLEHTASGLRLIPAPPTHSDVLTHTLIYGTPPSGAQQLNQDPRSLLHQQELQLQQRYQQLQQLQAQTQGLYTSQGSPVLYHQPSPGSSQPVAIPGATCHSPTQLQPPNTLNLQQQMQSLRISGCTPSGTGGSATPSPVGLVDPNFIVSNYVAASPQEERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQSESSLLLEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQEEKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHR--YDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6Z2D7-1", "uniprot_id": "A0A8M6Z2D7_DANRE", "id": "A0A8M6Z2D7-1", "name": "cGMP-dependent protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTLRDLQFALQLKIEELRQRDALIDELELELDAKDDLIRRLQGELDRLRLSSAPG-------------------------VSTATAGQQR--ASSLRARRKTLVTEPVTVEPKLVLQNQPISHSKSQESQRLIESALAENECMKYLDRDQLQCLVDSAYPTMLKQGVCLFQEGEHGAQAYIVEEGKLEVSRAGQRLHIIESGMMFEELGLIHNHTCSTTVTALANSRLWVMEAQVFQKLMQKSSVITITQSLQLLRSVPQLCVFSDDVLIRLADALEEVHYSDGDYIIQDGSPADKLFILSQGQVKVLEKQCVGEDSVMVCVLTRGDSFGESASQGDDVRSISVL--AAGDVTCLLIDREVFRKVTEGLDNGRKN--PSNKTRSKADEDGIAFGELSLSSFQVLCNLGEGQYGHTQLVHLKSDSSSKFALKSIRKQAIQSPGQRERVIAEKHILMDLQCPFIVRLHCTFKDAHCLYLLMEACEGGDLWILLRERGSLEEDAVRFYAACVLEALIALHHKGIVHRDLKPENVLLDQRGYAKLTGFGCAKKLDSLRRAWSFCGSVGFQPPEVILHQGHSLSADLWALGMLLYELLNGSPLFSDSEHMKVYRGTLKGTDELEFPKTISRTAAHLIKSLCRLKPTERLG-QRNGVKDVCRHMWFEGFDWEGLQKGTLTPPLKPNVPHVSDYGGTSLPTETYTEATPLDDSGWDIDF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : :: * ::: * ::: * .*: .*.: : .: . * : :** : . *.:.*: **: *: :*: ** *: *:: :**. **. :::**: *: .*::*:*::**:: * * : . :: **.:::* ::*: :: . .**.:: * **.:* ::.:* :: ::*:** : :.:: * :::*.***.**. *:**:::*: .*.:**:*:* * : :: :: : : :** ***.* **:*:*: .:: :* *:**:***: :.:: .*:: :. . : : * ::.*:.:.:: .** * :*:.:**: :.:. .**:* ::* * .. *:::: :** *: :. ***:*. **** : **:***:* **:** :**::*.:::.:.***:***:**: ** :.*::*******::*:.***.**..** ***: :::*:***: : .**:**::**.:*** *:**:*::***.*:* *:..: *:.*. *:* * :***:.*::.*::***.*** .*:**** :.*:.:: :* **:** * **:: ** **: * * * . . . ..* * :*** **", "identical_positions": 215, "similar_positions": 251, "identity": "19.72%" }, { "cls_id": "homologset.agr.FB:FBgn0000723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A584-1", "uniprot_id": "D4A584_RAT", "id": "D4A584-1", "name": "Tyrosine-protein kinase", "aln": "MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMS--LQDSGGQSWSSGPD--SPVSQSWAEITSQTENLSRVLRQHAEDLNSGPLSKLSVLIRERQHLRKTYNEQWQQLQQELTKTHSQDIEKLKSQYRTLTRDSAQARRKYQEAS-KDKDR-----DKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHQHYHQFMLPGLLQSLQDLHEEMAGILKDILQEYLEISSLVQDDVASIHRELAAAAARIQPEFEYLGFLRQYGSAPDVPPCVTFDVSLLEEGE-QLEPGDLQLNELTLESVQHTLTSVTDELAVATKEVLSRQEMVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLQRELQCE-EQNTHPRERVQLLGKRQVLQEAMQGLQVALCNQDKLQAQQELLQSKMEQLGTGEP----------------------PAVPLLQDDRHSTSSTEQERD---------------------------GGRTPTLEIIKSHFSGIFR-PKFSIPPP----------------------------------------------------------------------------------------------------------------------------------------------LQLVPEVQKPLHEQLWYHGAIPRAEVAELLTHSGDFLVRESQ-GKQ-EYVLSVLWDGQPRHFIIQSS-DNLYRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDK-WVLKHEDLVLGEQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN---LTNQQTREFVEKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTICQELQSIRKRHR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16879-1", "uniprot_id": "FES_MOUSE", "id": "P16879-1", "name": "Tyrosine-protein kinase Fes/Fps", "aln": "MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMS--LQDSGGQSWSSGPD--SPVSQSWAEITSQTENLSRVLRQHAEDLNSGPLSKLSVLIRERQHLRKTYNEQWQQLQQELTKTHSQDIEKLKTQYRTLVRDSTQARRKYQEAS-KDKDR-----DKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHHHHHRFMLPGLLQSLQDLHEEMAGILKDILQEYLEISSLVQDDVASIHRELAAAAARIQPEFEYLGFLRQYGSTPDVPPCVTFDESLLEDGE-QLEPGELQLNELTLESVQHTLTSVTDELAVATKEVLSRQEMVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLQRELQSE-EQNTHPRERVQLLSKRQMLQEAIQGLQIALCSQDKLQAQQELLQSKMEQLGTGEP----------------------PAVPLLQDDRHSTSSTEQERE---------------------------GGRTPTLEILKSHFSGIFR-PKFSIPPP----------------------------------------------------------------------------------------------------------------------------------------------LQLVPEVQKPLYEQLWYHGAIPRAEVAELLTHSGDFLVRESQ-GKQ-EYVLSVMWDGQPRHFIIQSS-DNLYRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDK-WVLKHEDLVLGEQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN---LTNQQTREFVEKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSIICQELHSIRKRHR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07332-1", "uniprot_id": "FES_HUMAN", "id": "P07332-1", "name": "Tyrosine-protein kinase Fes/Fps", "aln": "MGFSSELCSPQGHGVLQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMS--LQDSGGQSRAISPD--SPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQWQQLQQELTKTHSQDIEKLKSQYRALARDSAQAKRKYQEAS-KDKDR-----DKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHQHHHQLLLPGLLRSLQDLHEEMACILKEILQEYLEISSLVQDEVVAIHREMAAAAARIQPEAEYQGFLRQYGSAPDVPPCVTFDESLLEEGE-PLEPGELQLNELTVESVQHTLTSVTDELAVATEMVFRRQEMVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLQQELRNE-EENTHPRERVQLLGKRQVLQEALQGLQVALCSQAKLQAQQELLQTKLEHLGPGEP----------------------PPVLLLQDDRHSTSSSEQERE---------------------------GGRTPTLEILKSHISGIFR-PKFSLPPP----------------------------------------------------------------------------------------------------------------------------------------------LQLIPEVQKPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESQ-GKQ-EYVLSVLWDGLPRHFIIQSL-DNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDK-WVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN---LSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q7T0-1", "uniprot_id": "A0A2R8Q7T0_DANRE", "id": "A0A2R8Q7T0-1", "name": "Tyrosine-protein kinase", "aln": "MGFAEDLWCPQGHAALMKLQDSELRLMEVMKKWMMQRAKSDREFSMQLHQMSAMVEKMEGTQPGGGLNYISQFNKSWNVLVSQTESLSRIMRKHSDDLMVGPLSKLTLLIRDKQQLRKTYGEQWTLLNQDMCRVTQTELDRLKSSYRQLVRDATYAKKKYQEAS-KDRER-----DKAKERFIKATLKLHEHHNEYVLSVKAAQVHHQLHYGQSQPALLGALQTLQEEMVLILKEILQEYFDLSSLIQDEVVSVHTEMANALKAIQPHKEYDNFIQQNRYIREVPACVEFDCSLLEEAD-ALEPEDLQLNELTVEGIQHRLTAVEEELLGLASTLSSQQATVN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLELDLQDE-ERSANIGQRVYQFSKRNALEDSRQQVVLSMVVRARLEAQRRLLADKLQCLGTNEL----------------------PSLG-LDDDRISLTSSNSERDK--------------------------DHKHLNIDVIRNHLSSLFK-PKYTVPPA----------------------------------------------------------------------------------------------------------------------------------------------LTPVPDVEKPLTQQVWYHGAIPRMEVQELLKNDGDFLVRESQ-GKQ-EYVLSVHWGGQCRHFLIQST-DGVYRLDGEGFISVPLLVNHLFNSHQTVTKRTEIVLKKPIPKDK-WVLEHDDVILGQSIGRGNFGEVFSGRLRSDNTPVAVKACRENLPAEHKNKFLMEARILKQYDHPNIVKLIGVCTQKQPIYIIMELVQGGDFLTFLRTEGHNLKSSMLIRMAENVASGLAYLESKKCIHRDVAARNCLVGEESVVKISDFGMSREEQDGVYSATGGMKQIPVKWTAPEALNYGRYTTESDVWSFGVLLWETFSRGVTPYTIPTVMSNQQTRDEVERGYRMPAPNNCPDEIYTLMCQCWQYDPRKRPSFLKLKADLGALCQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09760-1", "uniprot_id": "FER_RAT", "id": "P09760-1", "name": "Tyrosine-protein kinase Fer", "aln": "MGFGSDLK--NSQEAVLKLQDWELRLLETVKKFMALRIKSDKEYAYTLQNLC---NQVDK-DSTVQVNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYVGIHQQIEAEMIKVTKTELEKLKSSYRQLIKEMNSAKEKYKEALAKGKET-----EKAKERCDKATMKLHMLHNQYVLALKGAQLHQSQYYDTTLPLLLDSVQKMQEEMIKALKGIFDEYSEITSLVTEEIVNVHKEIQMSVDQIDPSTEYNDFIDVHRTTAAKEQEIEFDTSLLEENE-NLQANEIMWNNLTADSLQVMLKTLAEELTQTQQMLLHKEAAVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEKRIEESSETCAKKSDIVLLLGQKQALEELKQSVQQLRCTEAKCAAQKELLEQKVQENDGKEP----------------------PPVVNYEEDARSVTSMER------------------------------KERLSKFESIRHSIAGIIKSPKSVLGSST-------------------------------------------------------------------------------------------------------------------------------------------QLSDVISVGEKPLAEHDWYHGAIPRIEAQELLKQQGDFLVRESH-GKPGEYVLSVYSDGQRRHFIIQFV-DNLYRFEGTGFSNIPQLIDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLK-DKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSG-LKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPG---MTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAIKKKIT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70451-1", "uniprot_id": "FER_MOUSE", "id": "P70451-1", "name": "Tyrosine-protein kinase Fer", "aln": "MGFGSDLK--NSQEAVLKLQDWELRLLETVKKFMALRIKSDKEYAYTLQNLC---NQVDK-ESTVQVNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYVGIHQQIEAEMIKVTKTELEKLKSSYRQLIKEMNSAKEKYKEALAKGKET-----EKAKERYDKATMKLHMLHNQYVLALKGAQLHQSQYYDTTLPLLLDSVQKMQEEMIKALKGIFDDYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENE-NLQANEIMWNNLTADSLQVMLKTLAEELTQTQQMLLHKEAAVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEKRIEESFETCEKKSDIVLLLGQKQALEELKQSVQQLRCTEAKCAAQKALLEQKVQENDGKEP----------------------PPVVNYEEDARSVTSMER------------------------------KERLSKFESIRHSIAGIIKSPKSVLGSST-------------------------------------------------------------------------------------------------------------------------------------------QVCDVISVGERPLAEHDWYHGAIPRIEAQELLKQQGDFLVRESH-GKPGEYVLSVYSDGQRRHFIIQFV-DNLYRFEGTGFSNIPQLIDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLK-DKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSG-LKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPG---MTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKELTVIKKMIT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16591-1", "uniprot_id": "FER_HUMAN", "id": "P16591-1", "name": "Tyrosine-protein kinase Fer", "aln": "MGFGSDLK--NSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLC---NQVDK-ESTVQMNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQIEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKET-----EKAKERYDKATMKLHMLHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENE-NLQANEIMWNNLTAESLQVMLKTLAEELMQTQQMLLNKEEAVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEKRIEESSETCEKKSDIVLLLSQKQALEELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEP----------------------PPVVNYEEDARSVTSMER------------------------------KERLSKFESIRHSIAGIIRSPKSALGSS--------------------------------------------------------------------------------------------------------------------------------------------ALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESH-GKPGEYVLSVYSDGQRRHFIIQYV-DNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLK-DKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSG-LKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPG---MTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASR9-1", "uniprot_id": "A0A8M3ASR9_DANRE", "id": "A0A8M3ASR9-1", "name": "Tyrosine-protein kinase", "aln": "MGFGRDLR--NSHEGLMKLQDWELKLLETVKRFMTLRVKSDKEYASLLINIS---QQVDKHDNSSQIHYVSHVSKSWTHMVQQTEQLSKIMKCHAEELNSGPLHRLTMMIKDKQQVKKSYQSLHQQIESEMNKVTKSDLERLKCTYRQLTKDAVLAREKYKDAVLKGKET-----EKARERYDKATMKLHNLHNQYVLAVKSAQLHQEHYHEFALPLLLDSLQKMQEEMISALKGILEEYSEITSLLTDEIVKVHKEIHTSIDQIDPLSEYDNFIEVYKSPEAKEPNVEFDATLLDETE-NLQANEILWNNLTADSLQVMLKSTTEELLITQQNLHSKEDLML--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLEKKMEESTKAYEKKSDVVLFLSQRQFLEELRQTVQLLRCSEAKLMAQRELLEQKMQENEGKEP----------------------PPVVNYEEDARSVNSMVMHHLDKS------------------------KDRISKFDTLRHSIAGIIRSPKSVLGSS--------------------------------------------------------------------------------------------------------------------------------------------SFFDVIPTSEKPLGEQEWYHGAIPRTEAQELLKQQGDFLVRESH-GKPGEYVLSVFSDGQRRHFIIQFA-DNQYRFEGTGFPTIPQLIDHHYTTKQVITKKSGVVLLNPVIKDKKWILNHEDVILGELLGKGNFGEVFKGTLR-DKTPVAVKTCKEDLPQDLKIKFLSEARILKQYDHPNIVKLIGVCTQRQPIYIVMELVPGGDFLSFLRKKKEDLKTKQLVKFALDAAGGMAYLELKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDDGIYSSSG-LKQIPIKWTAPEALNYGRYSSESDVWSYGILLWETFSLGMCPYPG---MTNQQAREQVEKGYRMSCPQKCPDEVYRVMQRCWEYKPENRPKFADIQKELAAVKKK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18106-4", "uniprot_id": "FER_DROME", "id": "P18106-4", "name": "Tyrosine-protein kinase Fer", "aln": "MGFSSALQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVA---QQGLKIDRADEMQG-SLISKSWRSYMDELDHQAKQFKFNAEQLEV-VCDKLTHLSQDKRKARKAYQEEHAKIAARLNHLT-DEVVRKKSEYQKHLEGYKALRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKLHLTHNEYVLSITEAIEVEKDFRNVLLPGLLEHQQSVQESFILLWRNILQEAAQYGDLTADKYKEIQKRIDTVIGSINPTEEYGEFTEKYKTSPTTPLLFQFDETLIQDIPGKLQSSTLTVDNLTVDWLRNRLQELEGAVRDCQEKQMKMIEHVNGGSPVANGSIISNGSNTSNGIQSNKDSLCRQSKDLNALRCQEKQKQKLVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLTLLRGRGRHFKRKSTPQPATPMTRSRQGRFNKLQPRSQSLGSLSVIRDGNGPSPARYEPITNHRLRQAASVHYLGEEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLTQLTAAVLTNTNNNHIYADLELDKKKDTSPSPECKGEQIQPKKEQIRIEINQTAPQNSIDAHLDRIDELNRVLDDRLKRTLQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNIFSNLKEFSKSPLVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNSNHSASQSTIITSTITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCKQCTKRRRIHPSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNG-HKHFIVQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRER-WELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEE--YIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSG---MTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDNSH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. * .: : *: **:*:* ::: : : *.*:*:: * :. :. . . * ..:** .: : :: :: ::::* :*: : ::::: :*:* : : : :: : * *: . : :::: * . :..::: :: **. **.***.: * . . * ** * ::*.: : *::: : .* :. :: .: *:* ** * . ** :*::: *:. : ::** : :: * : . : *: :. . . : :: :: . . :.: * . : : ::* . : :: : .. . ::** :. *:**.:** *. .** :.*******: .: : **** .* :**::* :. :*::* * .: *: * :. :* :: :* ..: ::: * *.::*: * : :*:****:*:.. *: : **:*:*: ** : * *** *.:*****.*****:***:*.*:**: *:**** **.:*::** . * : : :.*.*: *** * *****:******* : :*********:* * : ::*:*:*********:*:*:: .****:*:*:** ** * **. ::*.::*: :: * *:. *: *: : :* :** .. .** * : : : ", "identical_positions": 202, "similar_positions": 250, "identity": "15.1%" }, { "cls_id": "homologset.agr.FB:FBgn0000826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51956-1", "uniprot_id": "NEK3_HUMAN", "id": "P51956-1", "name": "Serine/threonine-protein kinase Nek3", "aln": "----MDDYMVLRMIGEGSFGRALLVQHESS----NQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKG--KLFPEDMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLSRGIVARLVQKCLPPEIIMEYGEEVLEEIKNSKHNTPRKKTNPSRIRIALGNEASTVQEEEQDRKGSHTDLESINENLVESALRRVNREEKGNKSVHLRKASSPNLHRRQWEKNVPNTALTALENASILTSSLTAEDDRGGSVIKYSKNTTRKQWLKETPDTLLNILKNADLSLAFQTYTIYRPGSEGFLKGPLSEETEASDSVDGGHDSVILDPERLEPGLDEEDTDFEEEDDNPDWVSELKKRAGWQGLCDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46308-1", "uniprot_id": "O46308_DROME", "id": "O46308-1", "name": "non-specific serine/threonine protein kinase", "aln": "MELGDSKLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELGLIKEEVYIISQLRHPHIVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGKVDFKSDVWSLGLVLYELCLGRSPFAAFLDKN--------------------------------------ATPALLHTVVQALVRPRLDCQLIRRLYDPVWAQV------------------------CELMVVYEQERRICLPDIFHLDAGMTVTLYKHYFSYSY-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .:*::*:*:***.:* :::. :: ..:*.* : :. :: ::*. ::::::**:** * .**. * : ***** .* * : *:* . . :: ::.:* :* :*::::* : *:*****.:*::* *.:**:.*** *.: : . : . . * .* : .: : ***:**** :***** : ** * ** **. * : :* **: * ::* . : * :: .. : **:*: . .*: :: .:. : :: . ", "identical_positions": 78, "similar_positions": 107, "identity": "15.12%" }, { "cls_id": "homologset.agr.FB:FBgn0000928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LTR3-1", "uniprot_id": "F1LTR3_RAT", "id": "F1LTR3-1", "name": "Putative ATP-dependent RNA helicase TDRD12", "aln": "-----MLEVLVLKIEDPGCFWV-IIKGCS----HFLEQEVDYQKLNSAMNDFYNSMCQDIE-IKPLMLEEGQVCVVYCQELKCWCRAVIKSIISSADHYLAECFLVDFAKYIPVKSKNIRVAVESFMQLPYRAKKFRLYCTKPVTLHIDFCEDNAEIVPATKWDSAAIQYFQNILRATTQVEAKLCAVEEDTFEVYLYATIKNEKVCVNDDLVAKNFAYYVSPMGNKN----------LNTLEKPRLSLNSVPCSSKLSPSLTLWPMLLQGKDCQRMENSQSLDFLAQSLQHTWCKDVVGDLG--PRAAVLDKAVNY-KDSLTDSPTIMFEKKQQSLPLKHMDKCIESSMYWPTKRGITIYADPDIPAASVFSQKPSE--KPLRLTEKKDCDEKNGCVKLLQFLNPDPLRADEISDLHQLQKVKLGTLQPGVVLRNRIEPCLTLDKSPLSADLKK------------------------ALQRNKFPGPSHTASYSWPPIARGCDVVVISHCGNDPLLYLPPLLTILQMGGCYKSLPSRNGPLAVIVCPG---WKKAQFIFELLGDYSMSSRPLHPVLLTIGLHKDEAKNMKLPRGCDVIVTTPHSLLRLLTYR----SLLFLRLCHLVLDEVHVLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWN-RHIEHLVREFMKDPHVVITALEEAALYGSVQQVVHLCLECEKTSTLLQVLDFVPSQAQKTLIFTCSVAETEIVCKVVESNSIFCLKMHKEMAFNLKSILEQWKKKLSSGSHIVLTLTDDCIPLLAITDATCVVHFSFPSSPKVFGGRLYCMSDHFQSLTEQGSPAEQGGKKTKSVLLLTERNASHAVGVLRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNETLPVFGHIRIIPFYISNATNYFGRIIDKHVDLY-------ETLNAEMNEYFKDPSNKTAAEKVENLGLYGLEEKTLFQRVQVLEASQKEDTWGLGSVLVKFIDEGRTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIIGKMHEAKVVFALGNTLWIDPMVHVTKLSNLKTSVIDYNVRAEILSMGMGIDNSEHVEQLKKLHKEAK---------------------------------------LPAFVDLPSQTSIPTTVEG-------------------TMCLQGTQRGDRGTERGAGSQVDPDNQKPGVLSEDIGHETISKATQPHVRSFHPQIKWFQKDDHIILKIKIRNVKDYKCKFFTDRVIFSAWVGDKFYLADMELQGDIRKDDCKCIIKDDEPLITLAKEKRACWCGLLKQRNPNVAFDFDHWEECEEDSPFSKVVSSKTLSCKAAALAESSSSSSDMTDGSESE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWU0-1", "uniprot_id": "TDR12_MOUSE", "id": "Q9CWU0-1", "name": "Putative ATP-dependent RNA helicase TDRD12", "aln": "-----MFEVLVLKIEDPGCFWV-IIKGCS----HFLEQEVDYQKLNTAMNDFYNSMCQDVE-MKPLMLEEGQVCVVYCQELKCWCRALIKSIISSADHYLAECFLVDFAKYIPVKSKNIRVAVESFMQLPYRAKKFRLYGTKPVTLHIDFCEDNAEIVPATKWDSAAIQYFQNLLRATTQVEAKLCAVEEDTFEVYLYATIKNEKVCVNDDLVAKNFAYYVSPMGNKN----------LNPLEKPRQSLNSVTCSSKLSPSLTLWPMLLQGKDYHRMEN---------------------------------KALNY-KDSLTDSPKMMLEKQQQSLPLKHTEKCTESSVYWPTKRGITIYADPDVPSVSGSSQRPNE--KPLRLTEKKDCDEKNGCVKLLQFLNPDPLRADGTSDLHQLQKVKLGTLQPGVVLRNRIEPCLTLEKSPLSADLKKMALTCLNSDTEDMKVAMEEMIPPEALQRNKFPGPSHTASYSWPPIARGCDMVVISHCGNDPLLYLPPLLTILQMGGCYKSLPSRNGPLAVIVCPG---WKKAQFIFELLGDYSMSSRPLHPVLLTIGLHKDEAKNMKLPRGCDVIVTTPHSLLRLLTYR----SLLFLRLCHLVLDEVHMLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWN-KHIDHLVREFMKDPCVVITALEEAALYGSVQQVVHLCLECEKTSTLLQVLDFVPSQAQKTLIFTCSVAETETVCK--------------------------------------------------------------------------------------GSPAEQGDKKTKSVLLLTERNASHAVGILRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNKTLPVFGHIRVIPFYISNATNYFGRIIDKHVDLY-------ETLNAEMNEYFKESSNKTSAEKVENLGLYGLEEKTLFQRVQVLEVSQKEDTWGLGSILVKLIDEGRTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIVGKMHDAKVVLALGNTLWIDPMVHVTKLSNLKTSIIDYNVRAEILSMGMGIDNSEHLEQLKKLYKEAK---------------------------------------LPAFEDLPCQTSIPTTVED-------------------TVCLQGTQQGDGGTERGAGSQEDSDNQKPGVLSEDIGSETISSAPQPHGRSFHPQIKWFQKDDVVILKIKIRNVKDYKCKFFTDRVIFSAWVGDKFYLADLELQGDIRKDDCKCIIKDDEPLITLAKEKQECWCGLLKQRNPNVAFDFDHWEECEEDSPFSKVVNSKNLSCKVAALAESSGSSSDTTDGSESE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q587J7-1", "uniprot_id": "TDR12_HUMAN", "id": "Q587J7-1", "name": "Putative ATP-dependent RNA helicase TDRD12", "aln": "-----MLQLLVLKIEDPGCFWV-IIKGCS----PFLDHDVDYQKLNSAMNDFYNSTCQDIE-IKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARLCAVEEDTFEVYLYVTIKDEKVCVNDDLVAKNYACYMSPTKNKN----------LDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQHTWCKGIVGDLR--PTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNE--KPLRLTEKKEYDEKNSCVKLLQFLNPDPLRADGISDLQQLQKLK-GLQPPVVVLRNKIKPCLTIDSSPLSADLKK------------------------ALQRNKFPGPSHTESYSWPPIARGCDVVVISHCESNPLLYLLPVLTVLQTGACYKSLPSRNGPLAVIVCPG---WKKAQFIFELLGEYSMSSRPLHPVLLTIGLHKEEAKNTKLPRGCDVIVTTPYSLLRLLACQ----SLLFLRLCHLILDEVEVLFLEANEQMFAILDNFKKNIEVEERESAPHQIVAVGVHWN-KHIEHLIKEFMNDPYIVITAMEEAALYGNVQQVVHLCLECEKTSSLLQALDFIPSQAQKTLIFTCSVAETEIVCKVVESSSIFCLKMHKEMIFNLQNVLEQWKKKLSSGSQIILALTDDCVPLLAITDATCVIHFSFPASPKVFGGRLYCMSDHFHAE--QGSPAEQGDKKAKSVLLLTEKDASHAVGVLRYLERADAKVPAELYEFTAGVLEAKEDKKAGRPLCPYLKAFGFCKDKRICPDRHRINPETDLPRKLSSQALPSFGYIKIIPFYILNATNYFGRIVDKHMDLY-------ATLNAEMNEYFKD-SNKTTVEKVEKFGLYGLAEKTLFHRVQVLEVNQKEDAWALDDILVEFIDEGRTGLVTRDQLLHLPEHFHTLPPQAVEFIVCRVKPADNEIEWNPKVTRYIHHKIVGKLHDAKVILALGNTVWIDPMVHITNLSSLKTSVIDYNVRAEILSMGMGIDNPEHIEQLKKLREDAK---------------------------------------IPACEESLSQT--PPRVTG-------------------TSPAQ--DQDHPSEEQGG-------------------------------------------------------------------------------------QGTPPAEDAACLQ-SPQPEDTGAEGGAESKTSSENQK-PGGYLVFKRWLSSNR-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJS0-1", "uniprot_id": "A0AB32TJS0_DANRE", "id": "A0AB32TJS0-1", "name": "RNA helicase", "aln": "-----MLEIQIIKIEDPGCLWARVLKGPG----LQVVSPEEYENLKVRMNLFYHEVDLDVQKLKPSELKEGLVCVVFSVALKSWCRAIVESVLQGVLDTQAWCLLVDYGDRIIVREDDVRTPLEKFLLLPFRVRRFRLAAVRPMTLQVPLSEDTAELVPSASWDSSATKYLLNLLQVSTLVEAVLCETQDDCSSIELYLTINNTKICVNHELVAKKFACFVSDADGSRSTDRAPVSLAWDIYSSPHQLLEMKGCCPLRAPPPDTPTRKQRTDHTHTEAEQQKAEAAEEIHTPSVGKPPVQKLRRNPGTYTIGRGWRIRAEATDLFTAQIHHSKSQYMKFTTLLQPKQIPESVEEKQSSPGQTDDNSEGSRVYNAIDSEELKEADLPQEPSLDDQLACARLMQFLNPDPLNPDQETVDAKVARCDPGHSGVLVHSAIRIEPCSNLTRAPITEQFRK------------------------FLLWRKYSGPNVAESYCWPAVARGFDTVLVSHSGDNPLSYIPPLLMILHTVSVVSSLAARTGPVAVILCPG---WEKVQTVLELLED-SKATHGLHPTSVLLGVDQDEPKKFKIQKNCQLLVTTPFSLLRLLEAQ----CFLFLRLCHLVLDEADLLYSQAPDQISIILKHFQQLVCAEERVACPRQIIAVGGRWS-AGIDGLVREHMIHPTVIITVMEEAALYGRVHQRVQLCLDCDKVSVLLSSLDFQPPKPQKTLIITNSAEETEHVYKAVVNTAVFTLKAHEDATDQFDFIIDQWKKDISQGTQVILVTTNDCLKALGIRDATCVVHYGFPSTPKLFGSRLFCMSENFRKLS-DVDHSEDWTPGAQSVLLLSEQNVRHVCGVLRYLRRTGALLPPELLQFALGIQQAKEEQKTHRPLCCSLKSFGFCRDSTVCPDRHTIN------TSLDQTQLPDSGMIMVLPLFIKTASVYCGRIVRQKEDLY-------EDLATQMKLHYAN--ERRCAVEVLKGALYAVQEENCYHRVRVLEVPEK-GEQLFSSVTACFIDEGRTQEVKSHQLLQLPAQFQDLPGQAVEIILCRVQPVDGEVDWNPKVTRAVSLKIRGKLHQARVVMSLGNTIWVDPMVRMVRVPGLKTFINEYNVHTEILASGFGVSNPQHVDLLKTVFQRDQNHNMLDQQLSEHRFESALLSSQQRMEVSEDFLTSRMKDLVSGHNAMFIQNNTAVVCNGGMKSGEDAELSARSAGSDLNGFASLIHTGPSSSESESDEAVDQLQTLNNNNNNTPQAPYNSKLFSFQLTSFHPQIKWFQRGESVTVCIKLISPVMQKCEFSCDAVVYSGYVNDRHYYAKLELFGDIIAEECSWEMKCNEPVMKLMKKDKRDWTTLLKHKSAFVSYEFDRIEEACVT------VNGHSFLAEVGEDGCYVSSESDSDSD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4W2-1", "uniprot_id": "Q9W4W2_DROME", "id": "Q9W4W2-1", "name": "RNA helicase", "aln": "MEPIGDLQVPSFKVVSGGTTFTYASPKSGAASLDFLAHTLRKREANTEKTILICQQNFEAERLKFELAERDVNTILLPPHGAMVGQVLLLWSKGYINQALILCDGMLEHLGVVEANLVIHTTLPELNKFEERLKWLSISARNAEMLVITPCDEENEKEGKGETEP-------------EIVQQRMPLKVDALNSMQLYEIKENTPPTSSEDYKAEADVLLSAATPATIP----------NDNKEQEINLSVEDATVKLLASFELGSTDSAAVDESSPAAAKFN-------------------------------APVYSPFVTENPTKSLDAEFQELVKSFKVQNVFKNMNLPPPPSVSIEEPVSSASASDYRHQIDT----TSLDSIRTVKDSPASLAVVPFSAGG---------------ITYNNYGVLGWSRHAVVPCYGLTEAPDISTIIR---------------------RAMQQMGVARSRARAVQRFAWPHVSLGKSVLVVGNLQIGKTWSYLPTVCQRSHEDLQRRPDVGRGPTCIFVCPNQGQGKQIERWMSTLLCLLGSASGFEDVVTHWDKTQLVDIVRRLKKPVGILLTSVDLLLQLLNHNPVGSIFDAQAVKCIALDNLNDMVRVLPNDTMKLLQRLPEMFQLTQN---KCQLLVSGRIWHTDLMVQHILPLMPDVLVLFDDALEASVYGGVQLDVRVVADEPEKIEHLKALIAERRNFANEPAVMVCSNSTEVLLLRRSLQAIG-VNAHICVSEACYSNVAEWLRQSPSG---LLLVTDDVVPRLKCGKIPLLIHYSFASMWARFKNRFSLFYAN--------LKSPTTRPVGQSVVFAKPTDLENIWKLCDFYMKHKLPRPGHLLGILS--QRRLEEQPTSRSLCHQMAAFGDCLR-HKCMYRHVMWR----DEVLPPDHYPKNGLIRFLVLVCYSPAALAVRLSDQFPTAIRFLNFPMSDLGERVQRHYELEANRHMHPNPVPGEMAVVKNINRYERVHIVSVESN-----VMVLVQLLDTSTECFSYKTSQLYSCDKIFKDSPREAMDLRILGLQPESLDRIWPDDARNLVRKDFFRRTHNKR--------------------NRQFHAVVQSAIHRTIFVR--NIYDDEGNDLLSFVINRFR-----------------------------------------SHQDECCQLKLDAMVMS-------------------------------------------------------------------------------------------------------------------------------SKDCPYM------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :*: . * :. . : .: : . : . : : :* :.. :: :.:: . * : : . ::. : .: : * : : : .. * : . : : . : *: : : .: ** :: ..: *: . : . : .. . :. . .. . . . . : : : . : . . . . * . .:. .. :: * . . : ** : :* : : . . . :.** :: * . :::.: . * : ** .:::**. :: : :. * :: :. . . : :: : :::*: **:** . : : : **: . : :: :*..: : . :. *::. * * : : * . ::: **::** *: *:: : : *. * : : . . .** : : :**:: . : : : : : * .* : . *:: : *.** : :** * * ** : * * * * .: : ..: *: : * .:: :: :: : : : : . :.**:::.. .: . : : . . . ** *: * :*::: : ::* . : * .. . : .: : *: : : : :: *: .: : : : *. : : : . * . .:. ", "identical_positions": 79, "similar_positions": 274, "identity": "5.52%" }, { "cls_id": "homologset.agr.FB:FBgn0000964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACF4-1", "uniprot_id": "D4ACF4_RAT", "id": "D4ACF4-1", "name": "Neural retina-specific leucine zipper protein", "aln": "-----------------------------------------------------------------------------------------MALPPSPLAMEYVNDFDLMKFEIKREPSE------------------------GRSGVPTASLGSTPYSSVPPSPTFSEPGMVGNS-----------------------------EAPRPAGLEELYWLATLQQQLGADEVLGLSPD------------------EAVELLQSQG------------------------------------------------------------PVSVEGPHGYYSGSPGETGAP-----------------------------------------------------NVQLPERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTS--------------GGPGSDD-HTH------LFL--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54846-1", "uniprot_id": "NRL_MOUSE", "id": "P54846-1", "name": "Neural retina-specific leucine zipper protein", "aln": "-----------------------------------------------------------------------------------------MAFPPSPLAMEYVNDFDLMKFEIKREPSE------------------------GRSGVPTASLGSTPYSSVPPSPTFSEPGMVGGG-----------------------------EAPRP-GLEELYWLATLQQQLGSDEVLGLSPD------------------EAVELLQNQG------------------------------------------------------------PVSMEGPLGYYSGSPGETGAQ-----------------------------------------------------HVQLPERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTS--------------GGPGSDD-HTH------LFL--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54845-1", "uniprot_id": "NRL_HUMAN", "id": "P54845-1", "name": "Neural retina-specific leucine zipper protein", "aln": "-----------------------------------------------------------------------------------------MALPPSPLAMEYVNDFDLMKFEVKREPSE------------------------GRPGPPTASLGSTPYSSVPPSPTFSEPGMVGAT-----------------------------EGTRP-GLEELYWLATLQQQLGAGEALGLSPE------------------EAMELLQGQG------------------------------------------------------------PVPVDGPHGYYPGSPEETGAQ-----------------------------------------------------HVQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTS--------------SGPGSGD-PSH------LFL--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54842-1", "uniprot_id": "MAFB_RAT", "id": "P54842-1", "name": "Transcription factor MafB", "aln": "--------------------------------------------------------------------------------MAAELSMG-PELPTSPLAMEYVNDFDLLKFDVKKEPLGR------------AERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFSP------------------------------------TEQKT-HLEDLYWMASNYQQMNP-EALNLTPE------------------DAVEALIGSHPVPQPLQSFDGFRSAHHHHHHHH------------------PHPHHGYPGAGVTHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHPG----------------------------PGPHAAAAATAAGSNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLAN---------SGFREAGSTSDS-PSSPE----FFL--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54841-1", "uniprot_id": "MAFB_MOUSE", "id": "P54841-1", "name": "Transcription factor MafB", "aln": "--------------------------------------------------------------------------------MAAELSMG-QELPTSPLAMEYVNDFDLLKFDVKKEPLGR------------AERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFSP------------------------------------TEPKT-HLEDLYWMASNYQQMNP-EALNLTPE------------------DAVEALIGSHPVPQPLQSFDGFRSAHHHHHHHH------------------PHPHHGYPGAGVTHDDLGQHAHPHHHHHHQASPPPSSAASPAQQLPTSHPG----------------------------PGPHATAAATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLAN---------SGFREAGSTSDS-PSSPE----FFL--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5Q3-1", "uniprot_id": "MAFB_HUMAN", "id": "Q9Y5Q3-1", "name": "Transcription factor MafB", "aln": "--------------------------------------------------------------------------------MAAELSMG-PELPTSPLAMEYVNDFDLLKFDVKKEPLGR------------AERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFSP------------------------------------TEQKT-HLEDLYWMASNYQQMNP-EALNLTPE------------------DAVEALIGSHPVPQPLQSFDSFRGAHHHHHHHH------------------PHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHPG----------------------------PGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLAN---------SGFREAGSTSDS-PSSPE----FFL--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54844-1", "uniprot_id": "MAF_RAT", "id": "P54844-1", "name": "Transcription factor Maf", "aln": "--------------------------------------------------------------------------------MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVE-------------TDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPASG------------------------------SEQKA-HLEDYYWMTGYPQQLNP-EALGFSPE------------------DAVEALISNS--HQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGGAPHYHHHHHHATGHHHHPTAGAPGAAGSASASASGAGGAGGGGPASAGGGGGGGGGG----TAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVS---------SGFRENCSSSDN-PSSPE----FFM--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54843-1", "uniprot_id": "MAF_MOUSE", "id": "P54843-1", "name": "Transcription factor Maf", "aln": "--------------------------------------------------------------------------------MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVE-------------TDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSG------------------------------SEQKA-HLEDYYWMTGYPQQLNP-EALGFSPE------------------DAVEALISNS--HQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAAPHYHHHHHHAAGHHHHPTAGAPGAAGGASASASGAGGAGGGGPASAGGGGGGGGGGG---TAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVS---------NGFRENGSSSDN-PSSPE----FFM--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75444-2", "uniprot_id": "MAF_HUMAN", "id": "O75444-2", "name": "Transcription factor Maf", "aln": "--------------------------------------------------------------------------------MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVE-------------TDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSG------------------------------SEQKA-HLEDYYWMTGYPQQLNP-EALGFSPE------------------DAVEALISNS--HQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVS---------SGFRENGSSSDN-PSSPE----FFM--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P0X6-1", "uniprot_id": "A0A8M9P0X6_DANRE", "id": "A0A8M9P0X6-1", "name": "Transcription factor Maf", "aln": "--------------------------------------------------------------------------------MASELALSSSDLPTSPLAMEYVNDFDLMKFEVKKEPLE-------------PDRSISQCSRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSG------------------------------NEQKA-HLEDFYWMTGYQQQLNP-EALGFSPE------------------DAVEALINST--HQLQS-YDGYARG-QQFSNTAGTGG----AMAGEEMGSAAAVVSAVIAAAAAQNG-APHHHHHHHHHGHHQQHQTPGVPSSTNSPVA----------------------------------------HHQHS--HLDDRFSDDQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRYKRVQQRHILEGEKTQLIQQVDHLKQEISRLVRERDAYKEKYEKLVN---------SGFRENSSSSDNNPSSPE----FFMSSRKFLHL------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8NHW3-1", "uniprot_id": "MAFA_HUMAN", "id": "Q8NHW3-1", "name": "Transcription factor MafA", "aln": "--------------------------------------------------------------------------------MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPE-------------AERF---CHRLPP-GSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKP-ALEDLYWMSGYQHHLNP-EALNLTPE------------------DAVEALIGSG--------HHGAHHGAHHPAAAA--------------------AYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGG---------------------------------AGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PG80-1", "uniprot_id": "M9PG80_DROME", "id": "M9PG80-1", "name": "", "aln": "MKMEDPTINDTYVQEFDLHHLEVGGNGAGQSHGAGAASQVTTLGHVKREDHSPPQPVAVKWTTIHGDPTNPDDDPDSLPLSGPEPAGAVEVSPSPHIKLRSFSGHHQWHMDERRLQPLSPPPEQYGPLPGQAILVNTSSGAGVPGGVPSTPPETPPVVGSPTGSSSCPAQTYAHHYARTPGSSVSVSASAAAAAAASAG----AASVSAGLSHDMMWLTNSIRADQQPLDLRPLPYPGSQEEAEEWDRQRDYALQAAAAHHHHHGQPLMQAQHHPHGHGGHPHQVMLQQSKYPHHHHHHFHNLELTPINMHSNSYGSASGALTPTCLPQVPSNGSGSSGGGGGSGSGSGGPGSVGGGSCVITRAALQPCRPLSASSTRSS-----NNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVRLKQKRRTLKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAAN---------GGVGAGGATAGGDSQSSP---EFYLXRQLAVASGSSASSSSSSQQQQQHPQQLHLQHRGPQWNPQQLVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. : :. ..... ::: :: * ::. :.* . *...: . . .: *:: : * * :* . . : :.* *.:::*****::*:* ::*.:****:*********** ** **::*:: ** . * ::. *: * .*: :*** : :: .. . . ::: ", "identical_positions": 47, "similar_positions": 72, "identity": "8.16%" }, { "cls_id": "homologset.agr.FB:FBgn0001075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEH1-1", "uniprot_id": "D3ZEH1_RAT", "id": "D3ZEH1-1", "name": "Protocadherin Fat 4", "aln": "--------MNLAANR----TPGRRRFPLPSPSLGQLLRVWGLLSLLP----------SPARVQAAEQRQVFQVMEEQPPGTLVGTIPTRPGFTYRLSESHALFAINSSTGALYTTATIDRESLPSDVVNLVVLSSSPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSGSGRQVILDTATDSDIGSNGVDHRSYRIVRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARR---------QYSLTVQATDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQRSKVPNLSLIKVASALDRERIPSYNLTVSVSDNSGAPPTAEVQARSSVASLVIFVNDINDHPPVFEQQVYRVNLSEEVPPGSYVSGVSATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTSAAGGLDRELASQIVLNISARDQGVHPKVSYAQLVVSVLDVNDQKPVFSQPEGYEVSVVENAPTGTELLVLGATDGDLGDNGTVRFSLQEAESDQR--LFRLDPVSGRLSTISSLDREEQAFYCLLILATDLGSP-PQSSTVQVNVSLLDINDNSPVFYPVQYFAHIQENE---------PGGSYVTTVSATDPDMGPNGTVKYSISAGDRSRFQIHAKSGVISTK--MALDREEKTAYQLQIVATDGGNLQSPSQAIVTVTVLDTQDNPPVFSQAA--YSFVVFENVALGYHVG--------SVSATTMDLNANISYLITTGDQRGMFAMNPVTGQLTTASVIDREEQSFYQLRVVASGGAVT---------GDAVVNITVKDLNDNAPHFLQAVES---IDAVENWQAGHSIFQAKAVDPDEGVNGRVLYSLKQNPKNLFTINEQNGNISLLGTLDVHAG-SYQVEIVASDMGVPQLSSSIILTVYVHDVNDNPPVFDQISYEVTLSESEPVNSRFFKVQALDKDSGANGEIAYAITDGNSGEAFGIFPDGQLYIKSELDRELQDRYVLLVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYAFEVAQPDFELHAITGEITNTHKFDRESLMRRRGTAVFS----------------FTVIATDQGLPQPLKDQATVHVYMKDINDNAPKFLKDFYQATVSETATNLTQVLRVSASDVDEGNNGLIHYSILKGNEERQFSIDRFSGQVTLVGKLDYEATPAYSLLIQAVDSG-TVPLNSTCTLSIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGVNADLHYTITGSNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPLGTSVISVTAHDPDADINGQLSYAIIQQMP---RGNHFSIDEVKGTIYTSAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPIFISQNALAADPSAMIG----SVLTTIMAADPDEGANGEVEYEIVNGDTDTFTVDRYSGDLRVAS-ALVPSQLIYNLIVSATDLGP--ERRKSTTELTVILQGLDG-----PVFTQTKYIT-ILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT--VGRLFTIGRQTGVIQTAAILDREQGACLYLVDVYAIEKSSAFPRTQRAEVEITLQDINDNPPVFPTDTLDLTVEENIGDGSKIMQLTAMDADEVGANALVTYALISGADDSFRIDPESGDLIATKRLDREHRSKYSLLVRADDGLQSSDMRINITISDVNDHTPRFSRPVYSFDIPEDTTPGSLVAAILATDDDSGVNGEISYVVEEDDGDGVFFLNPVTGVFNLTRALDYERQQYYILTVRAEDGG--GQFTTIRAYFNILDINDNPPVFSLSSYSTSLMENLPLGSTVLVFNVTDADDGVNSQLSYSIASGDSLGQFAVDKHGVLKALKALDRESQSFYNLVIQVHD---------------------------------LPQPPASRFTSTAQVSIILLDVNDNPPMFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPAGN--------KFSIGTIDGEVHLTGELDREEVSNYSLTVVATDKGQPPLSSSTEVVVMVLDINDNNPVFAQAMYRVQIKENTLTGTDIIQVSAADNDEGTNGQVRYGIVGGNTHQEFRIDSVTGAITVAKSLDRETIPAYILTVQATDRGSS-PRTDSCTVAITLLDMNDFVPVFELSPYSVNVPEN-LGALPRTILQVVARDDDQGP-NSQLSYVLLGGNEDNAFALTASGELRVTQSLDREARDHFVLVVTAADAGSPALTGTGTINIIVDDINDNVPTFASNMYFTAIPEDAPTGTDVLLVNASDADAATNAVISYSIIGGNSQ-FTINPSTGQIITSALLDRETKDNYTLVVVASDAGSPESLSSSTSVLVSVTDVNDNPPRFQHHPYVTHIPSPTPPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLSGAS------EVTFSVHVKDGGSFPKTDSTTVTVRFANKADFPKVR-AKEQTFMFPENQPVGTLVTTITGSSLRG---ETLSYYIASGNLGNAFQIDPLTGQVSISQP-LDFEKIQKYIVWIEARDGGFPPFSSYEKLDITVLDINDNAPAFEEDPFVSEILENLSP-RKILTVSATDKDSGPNGQLAYEIVNGNQESSFTINHATGEIRSIRPLDREKISYYELTVKSSDKGSPSQSTSVKVIISVLDENDNAPRFSQIFSAYVSENSPLGYTVTRVTTSDEDIGINAISRYSIADTALP-FTINPNTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNTPRFSRPSYYLDCPELTELGSRVTQVSATDPD-EGSNGQVFYFIKSKSEYFRINATTGEIFNKQVLKYQNVSGFSNVNINRHSFIVTASDRGNPSLLSETTVTINTVDSNDNPPQFLKNKYFTPVTKNVKVGTKLIKVTAVDDKDFGLNSEVEYFVSNGNHLGKFKLDNDTGWISIASSLVSDLNQNFFIRVTAKDKGNPPLSSQVVIHITVTEENYHTPEFSQSHISATIPESHSIGSVVRTVSARDRDTAMNGLISYNISSGNEEGIFAINSSTGVVTLAKALDYELSSKHEMTISATDGGWVARTGYCSLTVSVIDVNDNSPVFVPDEFFPTVMENAPSGTTVIHLNATDADSGANAVIAYTVQSSDSD--LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEEKCSFATVNIQLMGTNEYVPRFVSKLYYFEVSEAAPRGTAVGEVFASDRDMGADGEVHYLIFGNSRKKGFQIHKMTGQIYVSGLLDREKEERVSLKVLAKNFGNIRGADIDEVTVNITVLDANDPPVFSLNTYRVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTSGLDRESLPVYNLTVLAVDSGTPSATGSASLLVTLEDINDNGPVLTVS--EGEVLENKRPGTLVMTLQSTDPDLPPNQGPFNYYLLSTGPATNYFSLN-TAGVLSTTREIDREQIADFYLSVVTRDSGAPQMSSTGTVHITVLDQNDNPSQSRTVEIFVNYY-GNLFPGGTLGSVKPQDPDVLDSFHCSLTSG--VTSLFSIPAGSCDLSSQPRSTDGTFDLTVVSSDGVHSTVTNNIRVFFAGFSNATIDNSILLRVGVPTVKDFLTNHYLHFLRIASSQLTGLGTAVQLYAAYE----ENNRTFLLAAVKRNHNQYVNPSGVATFFESIKEILLRQSGVKVESVDHDPCIHA-PCQNGGSCLR--RLAVGSALKIQESLPVIIVANEPLQPFQCKCVPGYAGSWCEVDIDECLPAPCHNGGTCHNLVGGFSCSCSEGFTGRACERDIN-ECLPSPCKHGAVCQNFPGG--FNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVESYYCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTGERAEFLALEIAEERLRFSYN-LGSGTYKLTTMKKVSDGQFHTVIARRAGMAASLTVDSCSENQ------EPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRKGHVESHDFVGCIMEFAVNGRPLEPSQALAAQGILDQCPRLEGTCARNPCQHG---GTCVDFWSWQQCQCMEGLTGKYCEKSVTPDTALSLEGKGRLDYHMSQSEKREYLLT-------------QSIREATLEPFGVNS--------LEVKFRTRSENGILIHIQESSNYTTVKIKNGKVHFTSDAGVAGKVERIIPEAYVADGHWHTFRISKNGSSTVLSVDRTHSRDVVHPTQDFGGIEVLSMSLGGIPPNQAHRDTQTG-FNGCIASVLYGGESLPFSGKHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYKCVPPGDCASHPCQNGGSCEPGLLSGYTCSCPESHTGRTCETVVACLGVLCPQGKVCKAGSPGGHVCVQSQGPDEISLPLWAVPAIVGSCATALALLVLSLILCNQCRGKMPKNPKEEKKPKEKKKKGSENVAFDDPDNIPPYGDDLAVRKQPEGNPKPDIIERENPYLIFDETDIPHNSETIPSAPLASPEQ---EIEHYDIDNASSIAPSDADIIQHYKQFRSHT-PKFSIQRHSPLGFARQSPMPLGASSLTYQPSSYGQALRTSSLSHSACPTPNPLSR-HSPAPFSKPSAFYRNSPARELHLPLRDGG-----TLEMHGDPCQPGMFNYATRLGRRSKSPQAMASHG--SRPGSRLKQPIAQIPLESSPPVGLSIEEVERLNTPRPRNPSICSADHGRSSSEEDCRRPLSRTRNPADGIPAPESSSDSD--SHDSFTCSEMEYDRE------KPVVYTSRMPKLSQVNESDADDEDNYG--------ARLKPRRYHGRRAEG-GPVGTPAAASGAADSTL---------KLGQQAGNFNWDNLLNWGPGFGHYVDVFKDLASLPEKAAGNEEGKS-----GAAKPAAKDG--EAEQYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2PZL6-1", "uniprot_id": "FAT4_MOUSE", "id": "Q2PZL6-1", "name": "Protocadherin Fat 4", "aln": "--------MNLAANR----APGRRRLPLPSPSLCQLLRVWGLLSLLP----------GSARVQAAEQRQVFQVMEEQPPGTLVGTIPTRPGFTYRLSESHALFAINSSTGALYTTATIDRESLPSDVVNLVVLSSSPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSGSGRQVILDTATDSDIGSNGVDHHSYRIVSGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARR---------QYSLTVQATDRGVPSLTGRAEAFIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQRSKVPNLSLIKVASALDRERIPSYNLTVSVSDNSGAPPTAEVQARSSVASLVIFVNDINDHPPVFEQQVYRVNLSEEVPPGSYVSGVSATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTSAAGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTVLDVNDEKPVFSQPEGYEVSVVENAPTGTELLVLGATDRDLGDNGTVRFSLQEAENDQR--LFRLDPVSGRLSTASSLDREEQAFYCLSILATDLGSP-PQSSTAQVNVSLLDINDNSPVFYPVQYFAHIQENE---------PGGSYVTTVSATDPDMGPNGTVKYSISAGDRSRFQIHAKSGVISTK--MALDREEKTAYQLQVVATDGGNLQSPNQAIVTVTVLDTQDNPPVFSQAA--YSFVVFENVALGYHVG--------SVSATTMDLNANISYLITTGDQRGMFAMNPVTGQLTTASVIDREEQSFYQLKIVASGGAVT---------GDTVVNITVKDLNDNAPHFLQAVES---INAVENWQAGHSIFQAKAVDPDEGVNGRVLYSLKQNPKNLFTINEQNGNISLLGALDVHAG-SYQVEIVASDMGVPQLSSSILLTVYVHDVNDNPPVFDQISYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTITDGNNGDAFGIFPDGQLYIKSELDRELQDRYVLLVVASDRAVEPLSATVNVTVLLEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYAFEVTQPNFELHAVTGEITSTHKFDRESLMRRRGTAVFS----------------FTVTAMDRGLPQPLKDQATVHVYMKDINDNAPKFLKDFYQATVSETATNLTQVLRVSASDVDEGSNGLIHYSILKGNEERQFAIDSFSGQVTLVGKLDYEATSAYSLLIQAVDSG-AIPLNSTCTLSIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGVNADLHYTITGSNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIQVRDFNDNPPSFPPGDIFKSIVENIPLGTSVISVTAHDPDADINGQLSYAIIQQMP---RGNHFSIDEVKGTIYTSAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAMIG----SVLTTIMAADPDEGANGEVEYEILNGDTDTFTVDRYSGDLRVAS-ALVPSQLIYNLIVSATDLGP--ERRKSTTELTVILQGLDG-----PVFTQTKYIT-ILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT--VGRLFTIGRQTGVIQTAAILDREQGACLYLVDVYAIEKSSAFPRTQRAEVEITLQDINDNPPVFPTDTLDLTVEENIGDGSKIMQLTAMDADEG-ANALVTYALISGADDSFRIDPESGDLIATKRLDREHRSKYSLLVRADDGLQSSDMRINITISDVNDHTPRFSRPVYSFDIPEDTTPGSLVAAILATDDDSGVNGEISYVVEEDDGDGVFFLNLVTGVFNLTRALDYETQQYYILTVRAEDGG--GQSTTIRAYFNILDVNDNPPVFSMSSYSTSLMENLPLGSTVLVFNVTDADDGVNSQLSYSIASGDSLGQFAVDKHGVLKTLKALDRESQSFYNLVIQVHD---------------------------------LPQPPTSRFTSTAQVSIILLDVNDNPPMFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPSGN--------KFSIGTIDGEVHLTGELDREEVSNYSLTVVATDKGQPPLSSSTEVVVMVLDINDNNPVFAQAMYRVQIKENILTGTDIIQVSAADNDEGTNGQVRYGIVGGNTHQEFRIDSVTGAITVAKSLDRETTPAYTLTVQATDRGSS-PRTDSCTVAITLLDMNDFVPVFELSPYSVNVPEN-LGTLPRAILQVVARDDDQGP-NSQLSYVLLGGNEDNAFVLTASGELRVTQSLDREARDHFVLVVTAADAGSPALTGTGTINIIVDDINDNVPTFANNMYLTSIAEDARTGTDVLLVNASDADAAANAVISYSIIGGNSQ-FTINPSTGQIITSALLDRETKDNYTLVVVASDAGSPESLSSSTSVLVTITDVNDNPPRFQHHPYVTHIPSPTPPGSFVFAVTVTDADIGSNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLSGAS------EVTFSVHVKDGGSFPKTDSTTVTVRFANKADFPKVR-AKEQTFMFPENQPVGTLVTTITGSSLRG---ETLSYYIASGNLGDTFQIDPLTGQVSISQP-LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDINDNAPTFEEDPFVSEILENLSP-RKILTVSATDKDSGPNGQLDYEIVNGNQESSFTINHATGEIRSIRPLDREKISHYELTVKSSDKGSPSQSTSVKVIISILDENDNAPRFSQIFSAYVSENSPLGYTVTRVTTSDEDIGINAISRYSIVDTSLP-FTINPNTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNTPRFSRPSYYLDCPELPELGSRVTQVSATDPD-EGSNGQVFYFIKSQSEYFRINATTGEIFNKQVLKYQNVSGFSNVNINRHSFIVTASDRGNPSLLSETTVTINTVDSNDNPPQFLQNKYFTPVTKNVKVGTKLIKVTAVDDKDFGLNSEVEYFVSDGNHLGKFKLDNDTGWISIASSLVSDLNQNFLIRVTAKDKGNPPLSSQAVVHITVTEENYHTPEFSQNHISATIPESHSIGSVVRTVSARDRDTAMNGLISYNIISGNEEGIFAINSSTGVVTLAKALDYEMSSKHEMTISATDGGWVARTGYCSLTVSVIDVNDNSPVFVPDEFFPTVMENAPSGTTVIHLNATDADSGANAVIAYTVQSSDSD--LFVIDPNMGVITTQGFLDFETKQSYHLTVKAFNVPDEEKCSFATVDIQLKGTNEYVPRFVSKLYYFEVSEAASRGTAVGEVFASDRDMGADGEVHYLIFGNSRKKGFQINKMTGQIYVSGLLDREKEERVSLKVLAKNFGNIRGADIDEVTVNITVLDANDPPVFSLSTYRVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTSGLDRESLPVYNLTVLAVDSGTPSATGSASLVVTLEDINDNGPVLTVS--EGEVLENKRPGTLVMTLQSTDPDLPPNQGPFNYYLLSTGPATNYFSLS-TAGVLSTTREIDREQIADFYLSVVTRDSGAPQMSSTGTVHITVLDQNDNPSQSRTVEIFVNYY-GNLFPGGTLGSVKPQDPDVLDSFHCSLTSG--VTSLFSIPAGSCDLSSQPRSTDGTFDLTVVSSDGVHSTVTNNIRVFFAGFSNATIDNSILLRVGVPTVKDFLTNHYLHFLRIASSQLTGLGTAVQLYAAYE----ENNRTFLLAAVKRNNNQYVNPSGVATFFESIKEILLRQSGVKVESVDHDPCIHG-PCQNGGSCLR--RLAVGSALKIQESLPVIIVANEPLQPSQCKCVPGYAGSWCEVDIDECLPAPCHNGGTCHNLVGGFSCSCPEGFTGRACERDIN-ECLPSPCKHGAVCQNFPGG--FNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVESYYCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTGERAEFLALEIAEERLRFSYN-LGSGTYKLTTMKKVSDGQFHTVIARRAGMAASLTVDSCSENQ------EPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCVMEFAVNGRPLEPSQALAAQGILDQCPRLEGTCARNPCQHG---GTCVDFWSWQQCQCMEGLTGKYCEKSVTPDTALSLEGKGRLDYHMSQSEKREYLLT-------------QSIRDTTLEPFGVNS--------LEVKFRTRSENGILIHIQESSNYTTVKIKNGKVHFTSDAGVAGKVERIIPEAYIADGHWHTFRISKNGSITVLSVDRIHNRDIVHPTQDFGGIEVLSMSLGGIPPNQAHRDTQTG-FNGCIASVLYGGESLPFSGKHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYKCVPPGDCASHPCQNGGSCEPGLLSGYTCSCPESHTGRTCETVVACLGVLCPQGKVCKAGSPGGHVCVQSQGPDEISLPLWAVPAIVGSCATALALLVLSLILCNQCRGKMPKNPKEEKKPKEKKKKGSENVAFDDPDNIPPYGDDLAVRKQPEGNPKPDIIERENPYLIFDETDIPHNSETIPSAPLASPEQ---EIEHYDIDNASSIAPSDADIIQHYKQFRSHT-PKFSIQRHSPLGFARQSPMPLGASSLTYQPSSYGQGLRTSSLSHSACPTPNPLSR-HSPAPFSKPSAFYRNSPARELHLPLRDGG-----TLEMHGDPCQPGMFNYATRLGRRSKSPQAMASHG--SRPGSRLKQPIAQIPLESSPPVGLSIEEVERLNTPRPRNPSICSADHGRSSSEEDCRRPLSRTRNPADGIPAPESSSDSD--SHDSFTCSEMEYDRE------KPVVYTSRMPKLSQVNESDADDEDNYG--------ARLKPRRYHGRRAEG-GPVGTPAAASGAADSTL---------KLGQQAGNFNWDNLLNWGPGFGHYVDVFKDLASLPEKAAGNEEGKS-----GAAKPAAKDG--EAEQYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6V0I7-1", "uniprot_id": "FAT4_HUMAN", "id": "Q6V0I7-1", "name": "Protocadherin Fat 4", "aln": "--------MDLAPDR----ATGRPWLPLHTLSVSQLLRVFWLLSLLP----------GQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARR---------QYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRR--SFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSP-PQSSMARINVSLLDINDNSPVFYPVQYFAHIKENE---------PGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTR--MALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVA--YSFVVFENVALGYHVG--------SVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVT---------GDTMVNITVKDLNDNSPHFLQAIES---VNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAG-SYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFS----------------FTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSG-TIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMP---RGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIG----SVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVAS-ALVPSQLIYNLIVSATDLGP--ERRKSTTELTIILQGLDG-----PVFTQPKYIT-ILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT--VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEG-ANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG--GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHD---------------------------------LPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGN--------KFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGST-PRTDTSTVSIVLLDINDFVPVFELSPYSVNVPEN-LGTLPRTILQVVARDDDRGS-NSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR--IIGGNSQ-FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGAS------EVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVR-AKEQTFMFPENQPVSSLVTTITGSSLRG---EPMSYYIASGNLGNTFQIDQLTGQVSISQP-LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLP-FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPD-EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD--LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYY-GNLFPGGILGSVKPQDPDVLDSFHCSLTSG--VTSLFSIPGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVPTVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYE----ENNRTFLLAAVKRNHNQYVNPSGVATFFESIKEILLRQSGVKVESVDHDSCVHG-PCQNGGSCLR--RLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDIN-ECLQSPCKNGAICQNFPGS--FNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYN-LGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSENQ------EPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGRPLEPSQALAAQGILDQCPRLEGACTRSPCQHG---GTCMDYWSWQQCHCKEGLTGKYCEKSVTPDTALSLEGKGRLDYHMSQNEKREYLLR-------------QSLRGAMLEPFGVNS--------LEVKFRTRSENGVLIHIQESSNYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSGKHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVACLGVLCPQGKVCKAGSPAGHVCVLSQGPEEISLPLWAVPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPDNIPPYGDDMTVRKQPEGNPKPDIIERENPYLIYDETDIPHNSETIPSAPLASPEQ---EIEHYDIDNASSIAPSDADIIQHYKQFRSHT-PKFSIQRHSPLGFARQSPMPLGASSLTYQP-SYGQGLRTSSLSHSACPTPNPLSR-HSPAPFSKSSTFYRNSPARELHLPIRDGN-----TLEMHGDTCQPGIFNYATRLGRRSKSPQAMASHG--SRPGSRLKQPIGQIPLESSPPVGLSIEEVERLNTPRPRNPSICSADHGRSSSEEDCRRPLSRTRNPADGIPAPESSSDSD--SHESFTCSEMEYDRE------KPMVYTSRMPKLSQVNESDADDEDNYG--------ARLKPRRYHGRRAEG-GPVGTQAAAPGTADNTLP-------MKLGQQAGTFNWDNLLNWGPGFGHYVDVFKDLASLPEKAAANEEGKA-----GTTKPVPKDG--EAEQYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33450-1", "uniprot_id": "FAT_DROME", "id": "P33450-1", "name": "Cadherin-related tumor suppressor", "aln": "MERLLLLFFLLLAGRESLCQTGDTKLELLAPRGRSYATTYEQYAAFPRRRSSSSSPSGEMQSRAVDTSADFEVLEGQPRGTTVGFIPTKPKFSYRFNEPPREFTLDPVTGEVKTNVVLDREGMR-DHYDLVVLSSQPTYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQ-YEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDS-GLNGRTSVRIVSGNELGHFRLEEA--ADLHIVRVNGVLDREEIGKYNLTVVAMDQG-------TPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVT--TGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQRE-QNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPR-LQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLAS---AEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALG-GQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTL---GSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQN-DFDGTFEITES-GEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFK-HSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTN-EMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKN-PDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIG-GKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDIVGDYRCRLQKNPAQSQLQLAIPRACDLITTSHTTPIASVFSYTGNDGKHGDVSSKVSVAFQSFNNETLANSVSIMVRNMTAYHFLANHYRPILEMIKSRMSNE-DEVILYSLLEGGSGNSTNLQLLMAVRLAKTSYQQPKYLIERLR-EKRSAFSELLQKEVIVGYEPCSEPDVCENGGVCSATMRLLDAHSFVIQDSPALVLSGPRVVHDYSCQCTSGFSGEQCSRRQDPCLPNPCHSQVQCRRLGSDFQCMCPANRDGKHCEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCESVSDSCRPNPCLHGGLCVSLKPGYKCNCTPGRYGRHCERFSYGFQPLSYMTFPALDVTTNDISIVFATTKPNSLLLYNYGMQSGGRSDFLAIELVHGRAYFSSGGARTAISTVIAGRNLADGGWHKVTATRNGRVMSLSVAKCADSGDVCTECLPGDSSCYADEVGPVGTLNFNKQPLMIGGLSSADPILERPGQVHSDDLVGCLHSVHIGGRALNLSLPLQQKGILAGCNRQACQPALAAERCGGFAGQCIDRWSSSLCQCGGHLQSPDCSDSLEP---ITLGEGAFVEFRISEIYRRMQLLDNLYNSKSAWLDNQQMRERRAVSNFSTASQIYEAPKMLSMLFRTYKDQGQILYAATNQMFTSLSLREGRLVYYSKQHLTINMT-VQETSTLNDGKWHNVSLFSESRSLRLIVDGRQ----VGDELDIAGVHDF------LDPYLTILNVGGEAFVGCLANVTVNNELQPLNGSGSIFPEVRYHGKIESGCRG-DIGQDAAQVADPLSIGFTLVIVFFVILVVAILGS----------YVIYRFRGKQEKIG-SLSCGVPGFKIKHPGGPVTQS--QVDHVLVRNLHPSEAPSPP------VGAGDHMRPPVGSHHLVGPELLTKKFKEPTAEMPQPQQQQQRPQ---------------------------RPDIIERESPLIREDHHLPIPPLHPLPLEHASSVDMGSEYPEHYDLENASSIAPSDIDIVYHYKGYREAAGLRKYKASVPPVSAYTHHKHQNSGSQQQQQQHRHTAPFVTRNQGGQPPPPPTSASRTHQSTPLARLSPSSELSSQQPRILTLHDISGKPLQSALLATTSSSGGVGKDVHSNSERSLNSPVMSQLSGQSSSASRQKPGVPQQQAQQTS-MGLTAEEIERLNG-RPRTCSLISTLDAVSSSSEAPRVSSSALHMSLGGDVDAHSSTSTDESGNDSFTCSEIEYDNNSLSGDGKYSTSKSLLDGRSPVSRALSGGETSRNPPTTVVKTPPIPPHAYDGFESSFRGSLSTLVASDDDIANHLSGIYRKANGAASPSATTLGWEYLLNWGPSYENLMGVFKDIAELPDTNGPSQQQQQQTQVVSTLRMPSSNGPAAPEEYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ..* .* : * : . .: : :* . :..: *:*:* ** ** ** * *:* *:**:.*. *:::. ** : *. .:***.: * :****** **** ***: * *:***:* **:***.::*.*.: ** :::**:***:*:*.*** .: *.*: ** .:*** * ****: ::*** :.*.**** .*** :...* *.* * ********: *:*****:*. *.*:..: * *: *:.*: * *:* * * *:.* * * : * ::****:*:. * :: : . :** * *:* * **: . ::***.**:**::.**:** .: *:***** ***** ::*.*:** . **. **:*:.*** **.:: : .:* :::* ..****.* .***** . *: . **::.* *:* ***:*** ***.:. * . *** .*.**:*:.::*** *:*:**:::*.*:*** * ** :. :**:.* :* ****: . : *.***** * :**.:*:** * :** **: * *** * :*:: *:**. * : :: *** * * **:* *:* : * **.::*:*:* .****: : * : ::* * *:* ***: . : :.: *:***.* *** :*: : ::: : *:*:* * * *. ::* :.:*... **:.*:**.** : . . . *. *:* : * *.*: :* .:*** :.: .. : . * *.* :.*: : .*.::. . *::*.* * **: * :: :*::*** :*****: *:* ::**..: : *: :***:: *****:* * ** :. ** .*:.*: ::. * * ***. : ***.:**:: * *. .* : * .: ...* ::*::*:* * * ***.: *:* : ****:.****: ***.:*.*: **:*** : * * * * **.*:* * :**. **:**** *:::: **** :* *.* * . * . . *:.* *.: : * *** * *..:.:** : *: *.:****::***:*:* *.*: :::. :* :.: .* *.. : ****:*:: .* * : . . *.*:*: *:*:..*:* :.*:*****:**: *:.*:** *:: *:: :* :.*.*** ** ::**: **** ** :* :**::* :** *: : *:: * *:. **.*..::.* :******:*.*.:*: *.***. * : . *:*:*.* *::: ::*:. *.:.** *.. ***::* * **:* : *.*****.* * *. *:*: : * * ***** **. *.:.* *.**: *.:::***.***:.:**::**:* :* * :*.** *: .*.*:* ***** : *.*** *.*:* * * : : * **::* *:***.*:*:* ** *. . :.: : * *.*..:** : ***:.* : * ::* :* : .:. . . .:: *:* :.:** . ***.* . :*:* * .* * * * . :: : *.*****.:::: * . * :**::..* . . *.*** *. : *::.*** **** *. * *:**** . . ***.*::*.:*: * **.** * : .*.*:: * .* * * *.* . **: ::.* *..* ::*.:*.** . **** :***.* :*..**:* :: .* :**.**:.* *. .********:: * *. *:* * * * *.:::* * .* :.:* ** **::.** **** *:*** *:*:*.* . *** .* *:**:***.*:*. ***:.::**:*:.: *:.....* *.* *. : ***::** .:* :*.:*.::. : **** :* *.*.: .:* *.: .*::**.:*:*:: ****: * *:*.: * * **..*:***: .:*.* *.* *.**:* : :. .: **:.. **::::.. **** *.* *.:.* *:*:*. *:.::::: :** ***.*:* * ..: ** *: ::** *:* ***:**::**.** *: :::* *.. **.: *** *: * . * ***:* * . * *:. ::* :**:** *.* *** ..* ** : . :* * * * * . **:: *.* *:.* ::**:: : :.**** :..:.* :.* *:***.***** :.: *:*:*** *.* : * ::: *: :**.** .*:* * . ** : ::* : : * *:..**:* *:: **** .. * *.::..*:. .*. :**..: ::::***** *:*: .* . :*. *.***.. . * * * *: :**::***:.. *.*:. *.: : *. : *: : . * *. . :..: :** : **.. :. * :.*: ..::*.::.:* : : * **.* :*:::::* :* :*:.* **:* : * :**** **. *.: * : :.* * ***** ::: : :*:**: ** : * .*.* *:*** **:: *.: * : :.:* *..: *** : ****::. * :.::: *:* * : :..*:: :**:***.*:*:::** *.**: :* * ***:** *:* ** : **: : . * *:*.:*:*.:: *:**: *.* ::* * *..* ..* :** : * ***:*.*.:. * :. *** : : * *: *** * :*.*. : * ::. * * *:.:***:*.*: :::: : : . * ::: * ::*.*:*.* ** *.** **:::*.*:* : :*::*:.::. * ::::* * *.:*:* * *::* : * . *.:... ***::...: * .: : * *.*:* ** *.:. : *.** ** .**.** . .. :**...:** : **.* * *:. **:: *.* .***. *:::. ** :.: : ***:: .::.:.*:. * *: . :. . :*: : *****.*** .::. : ** * ** *:: :*:* ** **:* *:. .*..* :*::: . *.*:: :*:* :: * * :** * **.. *:*.: ::: *.**: *:*:. :::*::**::. ** ** * *:*:* * **.*:**:.*.*..***:*.. ** ***: ****.::** *.*:***:*.*** * **. * ::: *.**** * * ***..*:**:** *.*:*.* .. .:*** * .** : :*.*: ***:*:.:: **** . *** : *:*:* *. ****:: : ***:***** :* . :* : **: .** :*** ::***** * ***.* *:. * ..::*:. .:**: :* .:*** . : : ..*** *: .* : ***:******* :*::.* *. : *:* .. *..*:*:* *::..::* * .. :.* :*** : .::* : :: ..** *. *:.:: * * .*.* *: **: : : *. .**:*** :*.: .*:::. * **: * :... ** **: :..* :*. : :. *. : : * *.::.* . *:*** * ** . : ::* .::: . . :: *:* .*::*. *. * *** ***. *:.* ..*.* *. . *: **:: . * .**::*. **. *.. : *:*:.*: *: *** : *. ***::** * * .* *:*. * :*:*** ****: **** **:** ..* * : *** *.::******. *:* *::***:*:.. * ** . :. .: : ::::** :*.* * * * . **:* .*::. ** .: *. **:.: : : :**: * :***:* *:*.*.*:***: .. :.**.*: * .* :*** * * : . : * * *:* ** . *:* * . *..*: * ::* . :::::*: :* ** * . :. *.. * *.: *** .::* ::: .. :*::.:::*:: : *. :: :: : **:**.. : .:. * ** : *:.*:. : : * : :. * **:*.: ..* *:.*. *: . : . .:: **** :* . . .* *.*. . . * . : :.: * : . *. : : * * * :: .** * . *.* . * **: . : :: : * *:*. * ::::: .: :*******.* : *. ..:* :* : ****::********* **: *** :*. : : .*:. : ..*. * : : * . . .. *.*.. ** *..:*::: *. . *. : *.::* . : : ... *: : . ..** .. .*:. . * ..** * : * :.:. :**: **:**** ***. *: *: .. ***.* * . * : . .* ..**:.:* .::******:***.: * . .* : * *..: :..* . . . : *: *.* .:. *.:.* .*: . . * . .* .:.*: ******.: : :.****:*.**:. . .:: : .: : ..:* .*:**", "identical_positions": 1766, "similar_positions": 1685, "identity": "33.7%" }, { "cls_id": "homologset.agr.FB:FBgn0001077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09023-1", "uniprot_id": "HXB6_MOUSE", "id": "P09023-1", "name": "Homeobox protein Hox-B6", "aln": "------------------------------------MSSYFVNS-----TFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGP----------------------------GQDKGFAASSYYPPAGGGYGR-AAPCDYGPAPAFYREKDAACALS-------GADEPPPFHPEPR-KSD---------------CAQDKSVFGETEEQKCSTPVYPWMQRMNSCNS---------------SSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSA---------------------EEEEEKPAE---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09092-1", "uniprot_id": "HXA6_MOUSE", "id": "P09092-1", "name": "Homeobox protein Hox-A6", "aln": "------------------------------------MSSYFVNP-----TFPGSLPSGQDSFLGQLPLYPAGY-DALRPFPASYGASS----------------------------LPDKTYTSPCFYQQSNSVLACNRASYEYG-ASCFYSDKDLSGASPSGNNKQRGPGDYLHFSPEQQYKPDG--------------SVQGKALHEEGTDRKYTSPVYPWMQRMNSCAG---------------AVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQASG---------------------EDSEAKAGE---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10629-1", "uniprot_id": "HXC6_MOUSE", "id": "P10629-1", "name": "Homeobox protein Hox-C6", "aln": "------------------------------------MNSYFTNP-----SLSCHLAGGQD-VLPNVALNSTAY-DPVRHFST-YGAAV----------------------------AQNRIYSTPFYSPQENVVFSSSRGPYDYG-SNSFYQEKDMLSNCR---------QNTLGHNTQTSIAQDF--------------SSEQG--RTAPQDQKASIQIYPWMQRMNSHSG---------------VGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGG-----ATADSLGGKEEKREETEEEKQKE---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31268-1", "uniprot_id": "HXA7_HUMAN", "id": "P31268-1", "name": "Homeobox protein Hox-A7", "aln": "-----------------------------------MSSSYYVNA-----LFS-KYTAGASLFQNAEPTSCSFAPNSQR---SGYGAGA----------------------------GAFASTVPGLYNVNSPLYQSPFASGYGLG-ADAYG---NLPCASY--------DQNIPGLCSDLAKGACD--------------KTDEGALHGAAEAN---FRIYPWMR-----------------------SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18865-1", "uniprot_id": "HXC4_RAT", "id": "P18865-1", "name": "Homeobox protein Hox-C4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVVMLESRFP-------------------------------------------------------------------GP--ARG-VANCRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHDSPTPK-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02835-1", "uniprot_id": "FTZ_DROME", "id": "P02835-1", "name": "Segmentation protein fushi tarazu", "aln": "MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *.********:***:******:**::*.*:************** **: . ", "identical_positions": 40, "similar_positions": 11, "identity": "9.76%" }, { "cls_id": "homologset.agr.FB:FBgn0001078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50569-1", "uniprot_id": "STF1_RAT", "id": "P50569-1", "name": "Steroidogenic factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYSYDED------------------------------------------------------------------------------------------------------------------------LDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------AQIRANG--FKLETGPPMGVPPPPPPPPDYMLPPSLHAPEPKALVS------------------GPPSGPLGDFGAPSLPMAVPGPHG-PLAGYL-YPAFSNRTIKSEYPEPYASPPQQPGPPYSYPEPFSGG-------------------------------------------PNVPELILQLLQLEP---------EEDQVRARIVGCLQEP--AKSRPDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGKEDSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33242-1", "uniprot_id": "STF1_MOUSE", "id": "P33242-1", "name": "Steroidogenic factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYSYDED------------------------------------------------------------------------------------------------------------------------LDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------AQIRANG--FKLETGPPMGVPPPPPPPPDYMLPPSLHAPEPKALVS------------------GPPSGPLGDFGAPSLPMAVPGPHG-PLAGYL-YPAFSNRTIKSEYPEPYASPPQQPGPPYSYPEPFSGG-------------------------------------------PNVPELILQLLQLEP---------EEDQVRARIVGCLQEP--AKSRSDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGKEDSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13285-1", "uniprot_id": "STF1_HUMAN", "id": "Q13285-1", "name": "Steroidogenic factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYSYDED------------------------------------------------------------------------------------------------------------------------LDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------AQIRANG--FKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAA------------------GPPAGPLGDFGAPALPMAVPGAHG-PLAGYL-YPAFPGRAIKSEYPEPYASPPQ-PGLPYGYPEPFSGG-------------------------------------------PNVPELILQLLQLEP---------DEDQVRARILGCLQEP--TKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QWM1-1", "uniprot_id": "NR5A2_RAT", "id": "Q9QWM1-1", "name": "Nuclear receptor subfamily 5 group A member 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASSITGDFQDFLKHGLPAIAPAPGSETPHSPKLEEKHREKRAGLPDRHRRPIPARSRLVMLPKVETEASG-------LVRSHGEQGQMPENMQVSQFKMVNYSYDED------------------------------------------------------------------------------------------------------------------------LEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNQKRYTCIENQNCQIDKTQRKRCPYCRFKKCIDVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------ALIRANG--LKLEAMSQVIQAMPSDLT--SAIQNIHSASKGLPLSH---------------VALPPTDYDRSPFVTSPISMTMP-PHG-SLHGYQPYGHFPNRAIKSEYPDPYSSSPE-SMMGYSYMDGYQTSSP-----------------------------------------ASIPHLILELLKCEP---------DEPQVQAKIMAYLQQEQNNRNRQEKLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVDYSSIISNTEVAFNNLLSLAQELVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENFQLVEGVQEQVNAALLDYTLCNYPQQTEKFGQLLLRLPEIRAISKQAEDYLYYKHVNGDVPYNNLLIEMLHAKRA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45448-1", "uniprot_id": "NR5A2_MOUSE", "id": "P45448-1", "name": "Nuclear receptor subfamily 5 group A member 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASLDTGDFQEFLKHGLTAIASAPGSETRHSPKREEQLREKRAGLPDRHRRPIPARSRLVMLPKVETEAPG-------LVRSHGEQGQMPENMQVSQFKMVNYSYDED------------------------------------------------------------------------------------------------------------------------LEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNQKRYTCIENQNCQIDKTQRKRCPYCRFKKCIDVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------ALIRANG--LKLEAMSQVIQAMPSDLT--SAIQNIHSASKGLPLSH---------------VALPPTDYDRSPFVTSPISMTMP-PHS-SLHGYQPYGHFPSRAIKSEYPDPYSSSPE-SMMGYSYMDGYQTNSP-----------------------------------------ASIPHLILELLKCEP---------DEPQVQAKIMAYLQQEQSNRNRQEKLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVDYSTIISHTEVAFNNLLSLAQELVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENLQLVEGVQEQVNAALLDYTVCNYPQQTEKFGQLLLRLPEIRAISKQAEDYLYYKHVNGDVPYNNLLIEMLHAKRA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00482-1", "uniprot_id": "NR5A2_HUMAN", "id": "O00482-1", "name": "Nuclear receptor subfamily 5 group A member 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSNSDTGDLQESLKHGLTPIG---------------------AGLPDRHGSPIPARGRLVMLPKVETEALG-------LARSHGEQGQMPENMQVSQFKMVNYSYDED------------------------------------------------------------------------------------------------------------------------LEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------ALIRANG--LKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNH---------------AALPPTDYDRSPFVTSPISMTMP-PHG-SLQGYQTYGHFPSRAIKSEYPDPYTSSPE-SIMGYSYMDSYQTSSP-----------------------------------------ASIPHLILELLKCEP---------DEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90YL6-1", "uniprot_id": "NR5A2_DANRE", "id": "Q90YL6-1", "name": "Nuclear receptor subfamily 5 group A member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPKVESEYLG-------LARSHGEQGHMPGNMQAPQFKMMDYSYDED------------------------------------------------------------------------------------------------------------------------LDEMCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQSCQIDKTQRKRCPYCRFQKCLTVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKK--------ALIRANG--LKLEAMTQVMQTVPADLTITSAIQNIHSASKGLPLSHHHHHHHHHHHHSSSSAGLPPADFDRSPFVTSPVSMAMP-PHAGGLQGYQAYGHFQSRTIKSEYPDPYTSSPE-SLMGYPYVEAYAGGSP-----------------------------------------PSFPHLVVELLKCEP---------DEPQVQAKILAYLQQEQASRGKHEKLNTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHVFRQVMHAKEGSILLVTGQQVDYALIASQAGATLNNLLSHAQELVSKLRSLQLDQREFVCLKFLVLFSLDVKNLENFHLVESVQEQVNAALLDYVMCNYPQQTDKFGQLLLRLPEIRAISLQAEEYLYYKHLNGDVPCNNLLIEMLHAKRA---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QJG0-1", "uniprot_id": "F1QJG0_DANRE", "id": "F1QJG0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFRADED------------------------------------------------------------------------------------------------------------------------LEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCTQNQDCGIDKTQRKRCPFCRFQKCLSVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKR--------ALIRASG--FKLEANGTLLSG--------------QTEFSSVGLQS-------------------PYDCP-----PPALGVALQ-NYGSFPAQYQYTAPSLPKSIKAEYPDAYSSSPD-STLGYSYADGCLSASPHSV-----------------------------------PINPALPPLVLELQSCDP---------DEEQVRGKICAYLHQEQSGRGKLEKSRPFSLLCVMADQTLFSIVEWARSCVFFKELKVGDQMRLLHNCWSELLLLDHICRQVHHGRDGSLLLITGQEVELSAVLD-AGPPLSSMVERGQDLSRRLQLLQVDSREMACLKFLILFNPNVKLLENPQFVESVQEQVNGALLEYTLFSYPQCVERFSQLILRLPELRSLSAEAEDFLCYKHLCGEVPCNNLLIEMLHAKRSSAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33244-1", "uniprot_id": "FTZF1_DROME", "id": "P33244-1", "name": "Nuclear hormone receptor FTZ-F1", "aln": "MDTFNVPMLAESSNTNYATEATSNHHHLQHQHQQQHSHQQQQQQQLLMPHHHKDQMLAAGSSPMLPFYSHLQLQQKDATATIGPAAAAAAVEAATTSANADNFSSLQTIDASQLDGGISLSGLCDRFFVASPNPHSNSNMTLMGTATAATTTTTNNNNNNNTNNNNNNNVEAKTVRPSNGNSVIIESVTMPSFANILFPTHRSANECIDPALLQKNPQNPNGNNSSIIVPPVEYHQLKPLEVNSSTSVSTSNFLSSTTAQLLDFEVQVGKDDGHISTTTTTGPGSGSASGSGSGSGSGSGSIARTIGTATPTTTTSMSNTANPTRSSLHSIEELAASSCAPRAASPNSNHTSSASTTPQQQQQQQHHMQSGNHSGSNLSSDDESMSEDEFGLEIDDNGGYQDTTSSHSQQSGGGGGGGGGNLLNGSSGGSSAGGGYMLLPQAASSSGNNGNPNAGHMSSGSVGNGSGGAGNGGAGGNSGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDS---------SPSPIAIALGQVNASTGGVIATPMNAGTGGSGGGGLNGPSSVGNGNSSNGSSNGNNNSSTGNGTSGGGGGNNAGGGGGGTNSNDGLHRNGGNGNSSCHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVD---LFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFN---ELQNKLQDLKFDMGDYVCMKFLILLNPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAVRGEDHLYTKHCAGSAPTQTLLMEMLHAKRKG--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:: ::*:*******************************:* *** .:.* **********:***:**: ***:************************* * * * .: * :* . ...: . .:: : :: . . . ::: .* :: : : :: . *:: : . : * *:* : **.::* *:*** :.*::*:* *** **::.**::*::**: ::: . . * .*: .: : : . . :* :* *:.* : .*:**::*:. .:: : * *. :::.:.***:*.: ** ::* *: * *::::: ..::.* ** .. * :.**:***:**: ", "identical_positions": 144, "similar_positions": 125, "identity": "13.79%" }, { "cls_id": "homologset.agr.FB:FBgn0001079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y8C3-1", "uniprot_id": "A0A8I5Y8C3_RAT", "id": "A0A8I5Y8C3-1", "name": "Serine/threonine-protein kinase 36", "aln": "MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEEQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVRWPSTITSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSNLGTPFTSRLPPELQVLKDEQ-AHRLAPKGNQSRILRQACKRMAEEAKQKEDQNTGSTLDQEARLSKVTPSTAPVPGLKATPQESSLLAGLLASEMKNNWEDWGAGEAPP------TPRENHITLECEQAFPELRPETMGRRSTDAVDPENEEPDSDDEWQRLLETMEPVPVQLKSPLTLLCNPDFCQHIQSQLRGTGEQILKGVLDGASHLLPALRILSSLLSSCSDSVLLYSFCQEVGLPELPLSLLRYSQESSSIQQQPWYGAFLRELVAVVQAYFSCTFNLERSQTGDSLQVFEEAASLFLDLLGKLLAQPDDSEPTFRRDSLMCFAVLCEAVDGNSRAISKAFYASLLTTQRAVLDGLLHGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAISSALAAMCTAPVGLPSCWDAKEQVSWHLANQLTEDSSQLRPSLISGLRHHILCLHLLKVLYSCCYISERLCHILGQEPLALESLLMLVQGKVKVADWEESTEVALYLLSLLVFRLQDLPSGRAFLYEEQAWILSHHLLTLEEDSSMSGVCSTRKRKEPSQPIVICGASLCSRMEKLGSEVATLFTHSHIVSLVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPCSCGFYDGLLVLLLQLLTQ--GKPGLIRDVAGSEVWTILWHRFSMALRLSEEVSAQEDDLSLSSPPSLEPDWTLISPQGMAALLSLAMAIFTQEPQLCLSHLSQHGSVLMLTLKHLLSPSFLHRLSQAPQGSEFLPVVVLSVCKLLCFPFALDVDADLLGGILADLRASEVAVYLLQVCCHHLPLFQAELPIGLLTRLALMDPTSLKQFVNTVATSSRAIISFLSVVLLCDQPLMVSDLLSLLTHTTRILSPSHLSFIQELLSGSDESYRPLRSLLGHSENAVRVRTYRLLGHLLQHSMALRGALQSQSGLLNLLLLGLGDKDPAVRRSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDAQDAIRRNAASALGNLGPE-GLG-KELLKCQVPQRLLEMACGDPQPTVKEAALIALRSLRQEPCIHQVLVSLGASEKLTLLSLGHQLLPSSNSRPTSARHCRKLIHLLRPTHST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZM6-1", "uniprot_id": "STK36_MOUSE", "id": "Q69ZM6-1", "name": "Serine/threonine-protein kinase 36", "aln": "MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVRWPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSDLGTPFTSRLPPELQVLKDEQ-AHRLAPKGNQSRILRQACKLMAEEAKQKEDQNAGSALEQEDGLCKVTPSTAPVPGLKATPQESSLLAGILASEMKNNWEDWGAGEAPR------TSRENHINLECEQGFPEPRPEAMGRQSTDVVDPENEEPDSDDEWQRLLETSEPGPVQLKSPLTLLCNPDFCQRIQSQLRGTGEQILKGVLDGVSHLLPVLRILSSLLSSCNDSVLLYSFCQEAGLPELPLSLLRYSQESSSIQQQPWYGALLRDLVAVVQAYFSCTFNLERSQTGDSLQVFQEAASLFLDLLGKLLAQSDDSEQTFRRDSLMCFAVLCEAVDGNSWAVSKAFYSSLLTTQRAVLDGLLHGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAISSALAAMCTAPVGLPSCWDAKEQVSWHLANQLTEDSSQLRPSLISGLRHHVLCLHLLKVLYACCYISERLCHILGQEPLALESLLMLVQGKVKVADWEESTEVALYLLSLLVFRLQDLPSG---------------------------------------------------MEKLGSEVATLFTHSHVVSLVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPYSCGFYDGLLILLLQLLMQVQGKPGLIRDVVGSEVWTILWHRFSMALRLPEEVSAQEDDLLLSSPSSLEPDWTLISPQGMAALLSLAMAIFTQESQLCLSHLSQHGSVLMLTLKHLLSPSFLHHLSQAPQGPEFLPVVVLSVCKLLCFPFALDVDADLLVGVLADLRASEVVVCLLQVCCHHLSLLQAELPIGLLTRLALTDSASLKQFVNTVATSSRAIISFLSVVLLSDQPLMISDLLSLLTHTARILSPSHLSFIQELLSGSDESYRPLRSLLGHSENTVRVRAYGLLGHLLQHSMALRGALQSQSGLLNLLLLGLGDKDPAVRRSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDAQDGIRRNAASALGNLGPE-GLG-KELLKCQVPQRLLEMACGDPQPTVKEAALIALRSLQQESCIHQVLVSLGASEKLALLSLGNQLLPNSSNRPASVRHCRKLIQLLRPTHST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRP7-1", "uniprot_id": "STK36_HUMAN", "id": "Q9NRP7-1", "name": "Serine/threonine-protein kinase 36", "aln": "MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQ-AHRLAPKGNQSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILASELKSSWAKSGTGEVPS------APRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGNSRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYSCCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCG---------------------------------------------------MEKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTE-QGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGPE-GLG-EELLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B9P5-1", "uniprot_id": "A0A8M3B9P5_DANRE", "id": "A0A8M3B9P5-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDQYHILEVIGEGSFGRVYKGRRKFSGQVVALKFIPKVGRSEKDLRSLKREIDIMRGLKHPNIVLLLDSFETEREVVVVTEYAEGELFQILEDDGSLPEKQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSVSTLVLTSIKGTPLYMSPELVEEKPYDHSTDLWSLGCILYELHTGAPPFYTNSIFQLVQLIVRDPVKWPDNMSQDCLSFLKGLLMKEPEKRLSWPDLLHHPFVADGVLMVSDEGSS---NPLTVPPSPDVQALKHQQVAEKTTVRSGEGKLLGKARELREKEKTNRREVASGSAARCKTASAGGASNTGHSLGSTFSVYQNSSQPATNRHQANDNSVTRARSAPHKGQISRDYAREFPSVEVGPRQFLKRPGHVRTSLASVRMDSEEQDMDSDYEWQRLVELSDQGPVNAS----------ILQGLKIKLLQAKTQLLVRKGEETSSILLPLKVLRNIVQGCR-IGDVETVGKELELPHLLFSLIEDVLNIPDLMQESQGETVLADLMSVLIMYLEKSPGWEIKGR--------RAEDLCQLFISVFLSGDPKRSALLAAAVLTLFTQRGVSVNVGIEKLTAVLGDVLTYTEAHNPLPAGWGLCDGLLSLILHRLAECESSSLLDFQQSDLWPCLWAKVNIMLQNTPSQSCHFSPNGLYMFLSLALLLFSSDPYTCVTLLSDNTTNCSSTLGHLLTTSCSASLLERGLFWGDSEIN-SLSVMSCHLLCIPFSLDLPLEKHLSVLQSYQSSNIVAG-----------------------------------------------------------LVQMIQTIPIALVELPLCLLNRLLLS---------DPQHTTPCLITAAQASAFLPHGTESSDNGADHTQTQLKHS---GNGVERSKSNGIVKKTKIDHIKGDIKSKKSLDRPTGDVDASRDKN--------SSQNAPSRNIRQTKVKSQAKTYPTKAMEHLRDASKIGHIEELMDSLEIHGSSAGLSPQQGCGISMLIDSLEEFRRSGDRPKTSIR---SSPEEARTAGSLLALLLQSEALSGCAVELLILLSLLTRHPTYQSSFFLPVEFTQ------LRLALLHRDDGIRAACCSLLGHLG-------LCVIRVINEPKFDLFQDLLGCLCDPAPSVRRAACKAVGNWLNEIRKTSDNIPSKGLKSTTDMQTWSVQDKPRRTEGVRYMEADVWMQLAIG-----AARPLVSLLSDADNVIRQHCCGALANLAAF-SGGDGALLNADAPGLILQTACNDSHHAVRRAAVATLRVFSQQNTLLQALRSLDAGRKLCRSSQSSLFQRDYQWLVSKLDGSVEGKT--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23647-1", "uniprot_id": "FUSED_DROME", "id": "P23647-1", "name": "Serine/threonine-protein kinase fused", "aln": "MNRYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISWTQLLCHPFVEGRIFIAETQAEAAKESPFTN---PEAKVKSSKQSDPEVGDLDEALAALDFGESRQENLTTSRDSINAIAPS----------------------------------------------------------------------------------------DVEHLETDVEDNMQRVVVP---------------------------FADLSYRDLSGVRAMPMVHQPVINSHTCFVSGNS------------------NMILNHMNDNFDFQASLRGGGVAAKPIVAPTVRQSRSKDLE--------------------------------KRKLSQNLDNFSVRLGHSVDHEAQRKATEIATQEKHNQENKPP----------------------------------------AEAISYANSQPPQQQPQQLKHSMHSTNEEKLSSDNTPPCLLPGWDS--------------------------------------------CDESQSPPIENDEWLAFLNRSVQELLDG----------------------------------------------------------ELDSLKQHNLVSIIVAPLRNS------------------KAIPRVLKSVAQLLSLP------------------------------------------------------------------------------------FVLVDPVLIVDLELIRNVYVDVKLVPNLMYACKLLLSHKQLSDSAASAPLTTGSLSRTLRSIPELT----------------VEELETACSLYELVCHLVHLQQQFLTQFCDAVAILAASDLFLNFLT----------------------------------------------------------------HDFRQSDSDAASVRLAGCMLALMGCVLRELPENAELVERIVFNPRLN--------------------------------FVSLLQSRHHLLRQRSCQLLRLLARFSLRGVQRIWNGELRFALQQLSEHHSYPALRGEAAQTLDEISHFTFFVT-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::* : .::*:**** ***. :* ..:***:*.*.* **: *:*:.*:** :* * **::: :::***:. ::.***::* :*.: *. :* : *. .: :: :**********:******:****:** *. ******:** *: .* ************:***: *:**** :*:**:*** ** .* *** :.**::**.:* :: *:**..:: .**:*** *:* *:**.:** ***: . : : . . .*:* *: :. . :* . . * . . : .: : .. * *. : * : : *::: : : * :. ::.. ::. : .: . . . : . : . * . : . ::: : : .: : . . : *.: ..: . : .:: * : : :::: . : . :.: * . . * * .* .. : : .: : . ... * : * : . .*. : * * : .:. : : :..** . . :*:. . * *. * : : : : : : .. :: * :* : : : ", "identical_positions": 157, "similar_positions": 216, "identity": "11.41%" }, { "cls_id": "homologset.agr.FB:FBgn0001083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4X5-1", "uniprot_id": "A0A8I6A4X5_RAT", "id": "A0A8I6A4X5-1", "name": "CUB and sushi domain-containing protein 3", "aln": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEKHIRTAT----VANTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTSEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQ--GTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTVSVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR-----------------------------------------------TSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPN---------------SLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQIVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIRLPIGFGVHLQFVNFSTETIHDYLEVRSGSSELSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPG------YTLIGNSALTCLHG--VSRNWNHPLPRCEA------LCGGNITAMNGT--IYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIG------DIIRYQCLPGFTLVGNAILTCRLG--ERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKG---YNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESPPHGYIISQTG---GQLNSVVRWACDRGFRLVGKSSAVCR------------------------------KSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPD------LIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT--------KAQCQANRQWSHPPPVCKVVNCSDPGIPAN------------------------------------------------------SKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGMPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGNLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTMELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSG--EVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLADLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPANASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80T79-3", "uniprot_id": "CSMD3_MOUSE", "id": "Q80T79-3", "name": "CUB and sushi domain-containing protein 3", "aln": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEEHIRTATGAIDVASTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTPEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRFGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQ--GTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTISVNTDYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR-----------------------------------------------TSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPN---------------SLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIKLPIGFGVHLQFVNFSTETIHDYLEVRSGSSEISTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPG------YTLIGNSALTCLHG--VSRNWNHPLPRCEA------LCGGNITAMNGT--IYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIG------DIIRYQCLPGFTLVGNAILTCRLG--ERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKG---YNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESPPHGYIISQTG---GQLNSVVRWACDRGFRLVGKSSAVCR------------------------------KSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLDHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPE------LIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT--------KAQCQANRQWSHPPPVCKVVNCSDPGIPAN------------------------------------------------------SKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSG--EVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z407-1", "uniprot_id": "CSMD3_HUMAN", "id": "Q7Z407-1", "name": "CUB and sushi domain-containing protein 3", "aln": "MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQ--GTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR-----------------------------------------------TSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPN---------------SLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPG------YTLIGNSALTCLHG--VSRNWNHPLPRCEA------LCGGNITAMNGT--IYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIG------DIIRYQCLPGFTLVGNAILTCRLG--ERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKG---YNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESPPHGYIISQTG---GQLNSVVRWACDRGFRLVGKSSAVCR------------------------------KSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPE------LIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT--------KAQCQANRQWSHPPPMCKVVNCSDPGIPAN------------------------------------------------------SKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSG--EVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNC7-1", "uniprot_id": "A0A8M9PNC7_DANRE", "id": "A0A8M9PNC7-1", "name": "", "aln": "MKAADNEGWRGFLVLSHR-GCIRCAHG--------TTMTIKTGFIIGNIVFCCILTCVQGFIYTCGGTLKGKNGTIESPGFPHGYPNGANCTWVIVAEERSRIHIVFQSFAVEEEYDFLSLYDGHPHPANFRTRLTGFQVPAPVTSTGSIFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGIPAKGILNGSSFNVGDRIRYHCVSGYTLDGHAQLTCVTSTSNVAVWDFPIPICRAEDTCGGTFRGASGTISSPDFQKDYQSSGECTWTILADPGDTISLVFTEFQMDSKLDSLEVEGSDPPTIWLSGINIPVPIVSNKNWLRLHFVTDNSHRHKGFSAQYQ--------------------------------------------------------------------------------------------------------VKRSGDFKSRGVKLLPGKDNTSKFSIMNEGMVKQVSNFCPDPGEPENGKRIGTDYSIGATVQFTCDGDHVLQGSKSITCQRVAEVFAAWSDHRPVCKVKTCGMNLLGPSGTFTSPNFPIQYESNSQCVWIITASNPNKVIQINFEEFDLELGYDTLTVGDGGEVGDSKTIIQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGIPLYGLREGGGFSNGGVLRFECQFGFELIGERMISCQNNNQWSANIPICIFPCMSNFTAAMGTVLSPDYPEGYGNNLNCVWLIIAEAGSRIHLAFNDFDLEPPYDFLTVRDGDLADAVVLGRFSGAEVPSHLTSNSNILQLEFQADHSMSGRGFNITYSTFGHNECPDPGVPMNAKRFGNNFQLGSSISVVCEEGFIKTQ--GSDTIVCELEAGKVMWSGLIPKCEAPCGGHFTAPVGVILSPGWPGYYKDSLSCEWVIEAETGRSIKISFDRFQTELNYDFLEVHDGPNLLSPLIASLNGTQVPQFLFSSSNFLYLLFTTDNSRSNSGFKLFYESVTLDTHSCLDPGVPVNGVRYGQDLAIGSVVWFGCEPGYRLSHEEQLVCEKNHWWSHPLPTCDALCGGDVRGPEGIILSPGFPELYPNSLNCTWTLEVSHGKGVQFTFHAFHLEDHHDYLLLTENGSFVRPLARLTGSQRPPPVNAGLYGNFKAQLRFISDFSISFQGFNISFSEYDLEPCEDPGVPQFGRHSGGSFGIGDTLAFSCDPGYRLQGVPQISCLGGGRRIWSAPLPRCVAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPR-----------------------------------------------TSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPN---------------SLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTAIGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPG------YTLLGESSLTCLHG--VSRNWNHPVPRCEA------LCGGNITVLNGT--IYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIG------DIIRYRCLPGFTLLGSEILTCRLG--ERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKG---YNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTG---GHVNSVVRWACDRGFRLIGKNMAVCK------------------------------RTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPE------RIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPS--------EAQCQSDRQWSQHPPTCRVVNCTDPGIPAN------------------------------------------------------SIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSG--EIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0C6B8-1", "uniprot_id": "SVEP1_RAT", "id": "P0C6B8-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "-------------------------------------------------MWTRLAFCCWALALVSGWTNFQPMAPSLNFSFRLFPEASPGALGRLAVPPRSGEEEAVGSKVERLGRTFRSRVRRLRELSDRLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTMGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMAHCSYLCEAGRDCCDRMASCKCGTHTGQFECICEKGYYGKGLQYECTACPPGTYKPEASPGGISTCIPCPDENHTSPPGSTAPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTVEMSYNTVCLVTCNEGYRLEGHAKLTCQGNAQWDGTEPRCVERHCATFQKPKGVIISPPSCGKQPAKPGMICQLGCRQGYILSGIREVR-CATSGKWSARVQTAVCKDVEAPQISCPNDIKAKTEGQQDSANVTWQVPTAKDNSGEKVSVHVHPAFSPPYLFPIGEVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDLFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLTCREGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGKMVPSFCSDADDIDCRLED-LTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPADVGKTRSSRIKRTVPLSDPQIQLIFNITASVPLPEERNDTVELENQQRLIRTLETITNRLKSTLNKGPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSISECKAQCKQGTYSSSGLETCESCPLGTYQPDFGSRSCLPCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLAAPGPTQNKYEV----FHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDKVGGFTCECSSGYTGQICEENINECSSSPCLNKGTCTDGLASYRCTCVSGYVGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGT-----RCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGPHCELNINECQSNPCRNQATCVDELNSYSCKCRPGFSGRRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEGNKDNTFLLTDYN-------GWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDSGTGLSVG---------------KAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQL---NLWDYVLSPQQVKSLASSCPEELSRGNVLAWPDFVSGITGKVKVDSSSIFCSDCPSLEGSVPHLRPASGDRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWSQPLPHCERIRCGLPPTLENGFYSAEDLHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYICSCKPPYTGDGKNCAEPVKCKAPENPENGHSLGKIYSVGAEVTFSCEEGHQLVGVRKITCLESGEWDHLRPSCEAISCGAPPVPENGGVDGSAFTYGSKVRYRCDKGYTLAGDEESACLASGSWSHSSPVCELVKCSQPENINNGKYILSGLTYLSIASYSCEDGYSLQGPSLIECTASGSWDRAPPSCQLVSCGEPPMVKDALTTG---------------SNFTFGNMVTYTCKEGYTLAGPDTIICQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPEGQAVPRCIA-----------------------------------------------HFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGQWSPSPLSVQCIPVRCGEPPSITNGYPSGTNYSFGAVVAYSCHKG------FYIKGEKKSTCEA----TGQWSRPLPTCHP------VSCNEPPKVENG--FLEHTTGRTFESEARFQCNPGYKAVGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLRGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELTSEVGVMTISCKEGHALQGPSVLKCLP----SGQWNGSFPVCKLVLCQSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGNPIILCQVDGTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPG--FELVGNTTTLCGENGQWLGGKPMCRPIECPEPKEILNGQFSSVS----FQYGQTITYSCDRGFRLEGPKSLTCL------------------------------ETGN----WDMDAPSCNAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVVGHAMQTCEETGWSSSSPTCVPIDCGLPPHIDFGDCTRVS------------------------DGQGYFVQEDDMMEVPYLTP-HPQHLEATAKASEITEESLVPHASQFLYGTTVSYRCEPGYELLGIPVLVCQEDGTWNGTAPSCISIECDLPV------APENGFLHFTQTTMGSAAQYSCKPGHVLEGSHLRLCLQNKQWSGTVPRCEVISCSEPNPLGNGSIKGNDYSYLGVLHYECDSGYVLNGTE--------KRTCQENKQWDGHEPVCLPVDCGSPPVPTNGQVTGEEYTFQKEIAYSCGEGFILEGARSRVCLTNGSWSGTTPSCVPVRCPAPPQVANGVTDGLDYGFKKEVTFHCLEGYVLQGTPKLTCQSNGTWDAEVPICKPATCGPPADLPQGFPNGFSFFHGGHIQYQCFTGYKLHGNPSRRCLPDGSWSGSTPSCLP----CTCSTPIIQQGTVNATDLGCGKTVQIECFKGFKLLGLPEITCDANGQWSD-FPLCEHADCGPLPTVPN-GIVIKGSPSEDNVVTYSCRPGYIIQGSSDLICTEKGIWSEPYPTCEPVSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVVDT-DTDTFTCQQDGRWFPERINCSPKTCPVPSNRTRIRVHGDDFQVNRQVSVSCTEGFTYDGADRSTCQPDGTWEPPLSEESCIPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERVCQENRQWSGRVAVCRESRCEAPAEFPNGKAVLEN----TTSGPSLLFSCHRGYTLEGPPEAHCTANGTWSHLAPLCKPNPCPVPFVIPENALLSEREFYVNQNVSIKCREGFLLKGNGIITCNPDETWTQTNARCEKISCGPPTHVENAIARGVHYQYGDMVTFSCYSGYMLEGSLRSVCLENGTWTPPPICRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYRCDCPAGWTGSRCHTATCQSPCLNGGKCVRPNRCHCLSSWTGHDCSRKRRSGL----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AVA0-1", "uniprot_id": "SVEP1_MOUSE", "id": "A2AVA0-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "-------------------------------------------------MWSRLAFCCWALALVSGWTNFQPVAPSLNFSFRLFPEASPGALGRLAVPPASSEEEAAGSKVERLGRAFRSRVRRLRELSGSLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTKGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMARCSYLCEAGKDCCDRMASCKCGTHTGQFECICEKGYYGKGLQHECTACPSGTYKPEASPGGISTCIPCPDVSHTSPPGSTSPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTAEMSYNTLCLVTCNEGYRLEGSTRLTCQGNAQWDGPEPRCVERHCATFQKPKGVIISPPSCGKQPARPGMTCQLSCRQGYILSGVREVR-CATSGKWSAKVQTAVCKDVEAPQISCPNDIEAKTGEQQDSANVTWQVPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDMFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLSCKEGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGNMVPSFCNDADDIDCRLED-LTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPTDVGKARSSRIKRTVPLSDPKIQLIFNITASVPLPEERNDTLELENQQRLIKTLETITNRLKSTLNKEPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSVSECKAQCKQGTYSSSGLETCESCPLGTYQPEFGSRSCLLCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLVAPGHSQNKYEVSSQVFHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDQVGGFTCECSLGYSGQICEENINECISSPCLNKGTCTDGLASYRCTCVKGYMGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGT-----RCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGTHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGHRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEDDKDNTFLLTDYN-------GWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDGGTGLSIG---------------KAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQL---NLWDYVLSPQQVKLLASSCPEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSVPHLRPASGNRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHCERIRCGLPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCELVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITG---------------SNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIA-----------------------------------------------HFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKG------FYIKGEKKSTCEA----TGQWSKPTPTCHP------VSCNEPPKVENG--FLEHTTGRTFESEARFQCNPGYKAAGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLKGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELASEVGVMTISCKEGHALQGPSVLKCLP----SGQWNGSFPICKMVLCPSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGSPTILCQADSTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPG--FELVGNATTLCGENGQWLGGKPMCKPIECPEPKEILNGQFSSVS----FQYGQTITYFCDRGFRLEGPKSLTCL------------------------------ETGD----WDMDPPSCDAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVLGHAMQTCEESGWSSSSPTCVPIDCGLPPHIDFGDCTKVR------------------------DGQGHFDQEDDMMEVPYLA--HPQHLEATAKALENTKESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDLPV------APENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRCEAISCSKPNPLWNGSIKGDDYSYLGVLYYECDSGYILNGSK--------KRTCQENRDWDGHEPMCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGTWDAEVPVCKPATCGPPADLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLP----CRCSTPIIQQGTINATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWSD-VPLCEHAQCGPLPTIPN-AIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVMDS-DTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDFQVNRQVSVSCAEGFTHEGVNWSTCQPDGTWEPPFSDESCIPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLEN----TTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTWTPSPVCRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYQCDCPTGWTGSRCHTATCQSPCLNGGKCIRPNRCHCLSAWTGHDCSRKRRAGL----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4LDE5-1", "uniprot_id": "SVEP1_HUMAN", "id": "Q4LDE5-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "-------------------------------------------------MWPRLAFCCWGLALVSGWATFQQMSPSRNFSFRLFPETAPGAPGSIPAPPAPGDE-AAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENLTKKYCLEYNYDYENGFAIGPGGWGAANRLDYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTLNKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGT-----RCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYN-------GWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVG---------------LPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQL---NLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITG---------------NNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIA-----------------------------------------------HFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKG------FYIKGEKKSTCEA----TGQWSSPIPTCHP------VSCGEPPKVENG--FLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLP----SQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPG--FELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTD----LHYGQTVTYSCNRGFRLEGPSALTCL------------------------------ETGD----WDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLK------------------------DDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPT------APENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTE--------RRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLP----CRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDT-DTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIEN----RTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKRRTGF----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16109-1", "uniprot_id": "LYAM3_HUMAN", "id": "P16109-1", "name": "P-selectin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQ---KEVAAWTYHY-STKAYSWNISRKYCQNRYT-------DLVAIQNKNE----IDYLNKVLPYYSSYYWIGIR---------KNNKTWTWVGTK---------------KALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAP---GKWNDEH---------------------------------------------------------------------------------------CLKKKHALCYTASCQDMSCS-----------------------------------------------------------------KQGECLETIGNYTCSCYPGFYG--PECEYVRECGELEL---------------------------------------------PQHVLMNCSHPLG---------NFSFNSQCSFHCTDGYQVNGPSK----------------------------------------------------------LECLASGIWTNKPPQCLAAQCPPLKIPER-GNMTCLHS----------AKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAF------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYGSSCKFECQPG------YRVRGLDMLRCID----SGHWSAPLPTCEA------ISCEPLESPVHG--SMDCSPSLR-AFQYDTNCS------------------------------------------------------------------------------------------------------------------FRCAEGFMLRGADIVRCDN----LGQWTAPAPVCQALQCQDLP----------------------------------------------VPNEARVNCSHP---------FGAFRYQSVCSFTCNEG--LLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCT------------------------------RSGR----WTDSPPMCEAIKCPELFAPEQGSLDCS---------------------------------------------------------------------------------------------------------------------------DTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLP---------------------------------------------------TPGVQCPALTTPGQGTMYCR-HHPGTFGFNTTCYFGCNAGFTLIGDS--------TLSCRPSGQWTAVTPACRAVKCSELHVNKP------------------------------------------------------IAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTI-QEALTYFGGAVASTIG-----------LIMGG-TLLALLRKRFRQKDDGKCP----LNPHSHLGTYGVFTNAAFDPSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P98106-1", "uniprot_id": "LYAM3_RAT", "id": "P98106-1", "name": "P-selectin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGCPKGSWKPRLRSVVLGAAQLIWLSALISELVNR---KKVATWTYNY-STKAYSWNNSRAFCKRHFT-------DLVAIQNKNE----IAHLNDVIPYVNSYYWIGIR---------KINNKWTWVGTN---------------KTLTAEAENWADNEPNNKRNNQDCVEIYIKSNSAP---GKWNDEP---------------------------------------------------------------------------------------CFKRKRALCYTASCQDMSCN-----------------------------------------------------------------SQGERIETIGSYTCSCYPGFYG--PECEYVQECGKFDI---------------------------------------------PQHVLMNCSHPLG---------DFSFSSQCTFSCPEGYDLNGPSE----------------------------------------------------------MQCLASGIWTNNPPQ-------------------------------------------------------------------------CKAVQCQSLEAPLHGTMDCTHPLAAF------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYDSSCKFECQPG------YRMRGSDILHCTD----SGQWSEPLPTCEA------IACEPLESPLHG--SMDCFPSTG-AFGYNSSCT------------------------------------------------------------------------------------------------------------------FRCTEGFVLMGNDAIHCAD----LGQWTAPAPVCEALQCQEFP----------------------------------------------VPSKAQVSCSDP---------FGPLKYQSACSFSCDEG--SLLVGASVIRCLATGHWSEAPPECQAVSCTPLLSPENGTMTCIQPLGHSNYKSTCQFMCDEGFYLSGPERLDCS------------------------------PSGH----WTGSPPMCEAIKCPEIFAPEQGSLDCS---------------------------------------------------------------------------------------------------------------------------HVHGEFSVGSTCHFSCNEEFELLGSRNVECTVSGRWSAPPPTCKGVTSLP---------------------------------------------------VPSVRCPALTTPGQGTMSCR-HHLESFGPNTTCYFGCKTGFTLRGAN--------SLRCGASGQWTAVTPVCRAVKCSELHMDTA------------------------------------------------------VAMNCSNPWGNFSYGSTCAFHCPEGQSLNGSARTTCGEDGHWSDAMPTCQAGTLTI-QEALTYLGGALASTSG-----------LAVGG-TLLALLRKRLRKKDDGKCP----LNPHSHLGTYGVFTNAAYDPTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16581-1", "uniprot_id": "LYAM2_HUMAN", "id": "P16581-1", "name": "E-selectin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIASQFLSALTLVLLIKESG---------AWSYNT-STEAMTYDEASAYCQQRYT-------HLVAIQNKEE----IEYLNSILSYSPSYYWIGIR---------KVNNVWVWVGTQ---------------KPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDV---GMWNDER---------------------------------------------------------------------------------------CSKKKLALCYTAACTNTSCS-----------------------------------------------------------------GHGECVETINNYTCKCDPGFSG--LKCEQIVNCTALES---------------------------------------------PEHGSLVCSHPLG---------NFSYNSSCSISCDRGYLPSSMET----------------------------------------------------------MQCMSSGEWSAPIPA-------------------------------------------------------------------------CNVVECDAVTNPANGFVECFQNPGSF------------------------------------------------------------------------------------------------------------------------------------------------------------------------PWNTTCTFDCEEG------FELMGAQSLQCTS----SGNWDNEKPTCKA------VTCRAVRQPQNG--SVRCSHSPAGEFTFKSSCN------------------------------------------------------------------------------------------------------------------FTCEEGFMLQGPAQVECTT----QGQWTQQIPVCEAFQCTALS----------------------------------------------NPERGYMNCLP--------------------------------SASGSFRYGSS----------------------------------------CEFSCEQGFVLKGSKRLQCG------------------------------PTGE----WDNEKPTCEAVRCDAVHQPPKGLVRC--------------------------------------------------------------------------------------------------------------------------AHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQ-----------------------------------------------------------VVKCSSLA--------------------------------VPGKI--------NMSCS----------------------------------------------------------------------------------------GEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN-IPLVAGLSAAGLSLLT-----------LAP----FLLWLRKCLR-KAKKFVP----ASSCQSLESDGSYQKPSYIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P98105-1", "uniprot_id": "LYAM2_RAT", "id": "P98105-1", "name": "E-selectin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNASCFLSALTFVLLIGKSI---------AWYYNA-SSELMTYDEASAYCQRDYT-------HLVAIQNKEE----INYLNSTLRYSPSYYWIGIR---------KVNNVWIWVGTQ---------------KPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDS---GMWNDER---------------------------------------------------------------------------------------CDKKKLALCYTASCTNTSCS-----------------------------------------------------------------GHGECVETINSYTCKCHPGFLG--PKCDQVVTCQEQEY---------------------------------------------PDHGSLNCTHPFG---------LFSYNSSCSFSCERGYVPSSMETT---------------------------------------------------------VRCTSSGEWSAPAPA-------------------------------------------------------------------------CHVVECKALTQPAHGVRKCSSNPGSY------------------------------------------------------------------------------------------------------------------------------------------------------------------------PWNTTCTFDCEEG------YRRVGAQNLQCTS----SGVWDNEKPSCKA------VTCDAIPRPQNG--SVSCSNSTAGALAFKSSCN------------------------------------------------------------------------------------------------------------------FTCEHSFTLQGPAQVECSA----QGQWTPQIPVCKASQCEALS----------------------------------------------APQRGHMKCLP--------------------------------SASAPFQSGSS----------------------------------------CKFSCDEGFELKGSRRLQCG------------------------------PRGE----WDSEKPTCAG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQCSSLD--------------------------------LPGKM--------NMSCS----------------------------------------------------------------------------------------GPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPP-RPLVVALSVAATSLLT-----------LSS----LIYVLKRFFWKKAKKFVP----ASSCQSLQSFENYQGPSYII-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1NL34-1", "uniprot_id": "A0A8M1NL34_DANRE", "id": "A0A8M1NL34-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDICNKLQFFASFVLISSALNLW--RCSEGWSYHY-SDSTMTWQNARNWCRQHYT-------DLVAIQNKNE----IAHLNGILPRRNGYYWIGIR---------KINNQWTWVGTN---------------KTLTAEAENWAEKEPNNKGNNQDCVEIYIQREKDE---GKWNDES---------------------------------------------------------------------------------------CSKSKTALCYTASCASDSCVS----------------------------------------------------------------GHGECVETINSHTCSCFEGFYG--KVCENVVKCEPNEVNA-------------------------------------------LDHSSKQCSHPHG---------NFAYDSQCEYSCEEGYELKGSST----------------------------------------------------------TRCNFTAEWTSKPPS-------------------------------------------------------------------------CELVQCPQLNKPLKGGMQCNHPMGQFSYQSSCEF--------------------------------------------------------------------------------------------------------VCDEGYKLRDSSSSTLICGATGHWNDSQPTCEIVKCKAKDITPPAHAKVHCTNEDIPYKSQCEYSCEEG------YELKGSSTTTCTS----TTEWSSEPTTCEL------VQCPALEKPVNG--DLSCTLS----FSYGSKCS------------------------------------------------------------------------------------------------------------------FSCGEGFILTGVSETSCTK----TAEWSQEPPRCEVVQCSELA----------------------------------------------NPQKGGMQCNHP---------MGQFSYQSSCEFVCDEGYKLQNSSSSTLICGATGLWNDSQPTCEIVKCKARDLTTPANAKVHCTNENIPYESQCEYSCEEGYELKGSSTTMCT------------------------------STTE----WSNEPPTCELVQCPELAKPLEGDMYCNHPMGQFSYLSSCTFVCDEGYNLRDSSSSTLICGATGHWNDSQP-----------------------------------------------------------TCEIVKCKEEDITPPAHAKVHCTNEDIPYESQCEYSCEEGYELKGSSTTTCTSTTEWSSEPTICE-----------------------------------------------------------LIQCPALDNLVNGDLSC----NSSFSYGSKCSFSCAEGFILQGAS--------EISCTNTAEWSQKPPHCEAVVCPQLSDPAN------------------------------------------------------GYTNCS--SDEPFFGTICNFICFDGHQLDSNETVMCSHDGRWSGEVAVCQAQPGPS-KSLFKATEVALGVAGT-----------VGSSSLFLVYWILKKLKSNANKFKL----NSTLDTVDPPQAYKSSIDSLL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T6Z7-1", "uniprot_id": "A0AB32T6Z7_DANRE", "id": "A0AB32T6Z7-1", "name": "E-selectin", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQCNCLNSKSHLTVILYALLCKFPFRFHANKTELCQKKMVLLVHITLFSGSLVFMTGMYNVNAWTYHYNIDSKLDWTAARQWCQTHFT-------DMVAIQNQAE----IAYLNEILPFHRAYYWIGIR---------KIDGHWTWVGTK---------------KRLTVEAANWATNEPNNQGTGEDCVEIYIKRNKDT---AKWNDER---------------------------------------------------------------------------------------CSKKKATVCYLASCTEISCS-----------------------------------------------------------------EHARCVETIGNYTCQCDAGFMG--PRCEEVVQCQPVEN---------------------------------------------PQQGLVKCDGAFG---------EFNFNSSCQFQCATGFNLVGAER----------------------------------------------------------IHCLTTGHWNDTLPVCQAVKCQAIIDAPRGWTMICTHP----------LSMNSFNSSCEFECKEGFELNGSKTTWCDHTGHWTDKAPTCTVVTCNPLLAPANSSLACADPLGKS------------------------------------------------------------------------------------------------------------------------------------------------------------------------SFRSSCNVTCDEG------YKLRGRAALTCQR----EGNWSAPLPVCEV------VKCDSLKPIANG--SYQCHDSVD-EFSYGSTCW------------------------------------------------------------------------------------------------------------------FKCDSGFVHNGTNSTHCTK----QGNWSHISPICHAVQCPPLSD---------------------------------------------TPKYGSVSCVHP---------LSTNSYNSSCEFKCEEG--LVLRGTDSTHCDHTGHWTNTAPICTAVACDPLVTPVNSNLTCANPLGKFSFRTSCEVICEVGYKLRGDTTLNCL------------------------------SNGN----WSAPTPACKVIRCEALESVHHGSVHCHDLLEEFSYGSECWLECEAGFTLNG--TNSTYCTSQGKWKQELS-----------------------------------------------------------VCQAQQCSSLTDPSHGSLTCTHPHGQFSFGTVCEVSCQAGFKLHGTPKMECLEMGKWTDTPPFCL-----------------------------------------------------------AQECPLLSAPENGWMNCS-HPHSLFSYESQCLLGCETGFELTGEP--------DIQCSASGNWSQEMPSCAVVHCEPLWLTHLSDL------------------------------------------------GPPPSMNCSHPHGNFSFGSQCMFWCANSHELNGTSQLVCTSNGYWTHSPPICVVKEMSVSASMLIYAAVGAVSSAG-----------LLLLG-GLIFLLTRQITKKAHYSLN----KSSLEGDLNLAFELN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02749-1", "uniprot_id": "APOH_HUMAN", "id": "P02749-1", "name": "Beta-2-glycoprotein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKT------------------------------------------------------------------FYEPGEEITYSCKPGYVSRGGMRK---------------------------------------------------------FICPLTGLWPINTLK-------------------------------------------------------------------------CTPRVCPFAGILENGAVRYTT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEYPNTISFSCNTG------FYLNGADSAKCTE----EGKWSPELPVCAP------IICPPPSIPTFA--TLRVYKPSAGNNSLYRDTA-----------------------------------------------------------------------------------------------------------------VFECLPQHAMFGNDTITCTT----HGNWT-KLPECREVKCPFPS----------------------------------------------RPDNGFVNYPAKP--------------------------------------------------------------------------TLYYKDKATFGCHDGYSLDGPEEIECT------------------------------KLGN----WSAMPSCKASCKVP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKKATVVYQ----------------------------GERVKIQE--------KFKNG------------------------------------------------------------------------------------------MLHGDKVSFFCKNKEKKCSYTEDAQCIDG--TIEVPKCFKEHSSL-----------------------------------------AFWKTDASDVKP----C------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26644-1", "uniprot_id": "APOH_RAT", "id": "P26644-1", "name": "Beta-2-glycoprotein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MISPALIFFSAFLCHVAIAGR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------RMWPINTLK-------------------------------------------------------------------------CTPRVCPFAGILENGVVRYTT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEYPNTIGFACNPG------YYLNGTSSSKCTE----EGKWSPELPVCAR------ITCPPPPIPKFA--ALKEYKTSVGNSSFYQDTV-----------------------------------------------------------------------------------------------------------------VFKCLPHFAMFGNDTVTCTA----HGNWT-QLPECREVKCPFPS----------------------------------------------RPDNGFVNYPAKP--------------------------------------------------------------------------VLSYKDKAVFGCHETYKLDGPEEVECT------------------------------KTGN----WSALPSCKASCKLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKKATVLYQ----------------------------GQRVKIQD--------QFKNG------------------------------------------------------------------------------------------MMHGDKVHFYCKNKEKKCSYTEEAQCIDG--TIEIPKCFKEHSSL-----------------------------------------AFWKTDASDVTP----C------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01339-1", "uniprot_id": "APOH_MOUSE", "id": "Q01339-1", "name": "Beta-2-glycoprotein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSPVLALFSAFLCHVAIAGRICPKPDDLPFATVVPLKT------------------------------------------------------------------SYDPGEQIVYSCKPGYVSRGGMRR---------------------------------------------------------FTCPLTGMWPINTLR-------------------------------------------------------------------------CVPRVCPFAGILENGIVRYTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEYPKNISFACNPG------FFLNGTSSSKCTE----EGKWSPDIPACAR------ITCPPPPVPKFA--LLKDYRPSAGNNSLYQDTV-----------------------------------------------------------------------------------------------------------------VFKCLPHFAMIGNDTVMCTE----QGNWT-RLPECLEVKCPFPP----------------------------------------------RPENGYVNYPAKP--------------------------------------------------------------------------VLLYKDKATFGCHETYKLDGPEEAECT------------------------------KTGT----WSFLPTCRESCKLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKKATVLYQ----------------------------GMRVKIQE--------QFKNG------------------------------------------------------------------------------------------MMHGDKIHFYCKNKEKKCSYTVEAHCRDG--TIEIPSCFKEHSSL-----------------------------------------AFWKTDASELTP----C------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04003-1", "uniprot_id": "C4BPA_HUMAN", "id": "P04003-1", "name": "C4b-binding protein alpha chain", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLGNCGP------------------------PPTLSFAAPMDITLTETRFKTGTTLKYTCLPG-----------------------------------------------------------------------------------------------------YVRSHSTQTLTCN----------------------------------------------------------------------SDGEWVYNTFCIYKRCRHPGELRNGQVEIKTD--------------------------------------------------------------------------LSFGSQIEFSCSEGFFLIGSTTS----------------------------------------------------------RCEVQDRGVGWSHP----------------------------------------------------------------------LPQCEIVKCKPPPDIRNGRHSG-EENFYA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGFSVTYSCDPR------FSLLGHASISCTVENETIGVWRPSPPTCEK------ITCRKPDVSHGE--MVSGFGPIYNYKDTIV---------------------------------------------------------------------------------------------------------------------FKCQKGFVLRGSSVIHCDA----DSKWNPSPPACEP-------------------------------------------------------------------------------------------------------------------NSCINLPDIPHASWETYPRPTK-EDVYVVGTVLRYRCHPGYKPTTDEPTT--------------------------------VICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPAN------------------------------------------------------------------------------------------------------------------------HCVYFYGDEISFSCHETSRFSAICQG----DGTWSPRTPSCGDI---------------------------------------------------------CNFPPKIAHGHYK------QSSSYSFFKEEIIYECDKGYILVG----------QAKLSCSYSHWSAPAPQCKALCRKPELVNG---------------------------------------------------------RLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVL-------TGKRLMQCLPNPEDVKMALEVYKLSLEIEQLELQRDS-------ARQSTLDKEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63514-1", "uniprot_id": "C4BPA_RAT", "id": "Q63514-1", "name": "C4b-binding protein alpha chain", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLTAALWVAVFGKCGP------------------------PPDLPYALPAS-EMNQTDFESHTTLRYNCRPG-----------------------------------------------------------------------------------------------------YSRASSSQSLYCK----------------------------------------------------------------------PLGKWQINIACVKKSCRNPGDLQNGKVEVKTD--------------------------------------------------------------------------FLFGSQIEFSCSEGYILIGSSTS----------------------------------------------------------YCEIQGKGVSWSDP----------------------------------------------------------------------LPECVIAKCGMPPDISNGKHNGREEEFFT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YRSSVTYKCDPD------FTLLGNASITCTVVNKTVGVWSPSPPTCER------IICPWPKVLHGT--INSGFKHTYKYKDSVR---------------------------------------------------------------------------------------------------------------------FVCQKGFVLRGSGVIHCEA----DGSWSPVP-VCEL-------------------------------------------------------------------------------------------------------------------NSCTDIPDIPNAALITSPRPRK-EDVYPVGTVLRYICRPGYEPATRQPMT--------------------------------VICQKDLSWSMLRGCKEICCPVPDPKSVRVIQHEKAHPDN------------------------------------------------------------------------------------------------------------------------DCTYFFGDEVSYTCQNDIMLTATCKS----DGTWHPRTPSCHQS---------------------------------------------------------CDFPPAIAHGRYT------KSSSY-YVRTQVTYECEEGYRLVG----------EATISCWYSQWTPAAPQCKALCRKPEIGNG---------------------------------------------------------VLSTNKDQYVETENVTIQCDSGFVMLGSQSITCSENGTWYPKVSRCEQEVPKDCEHVF-------AGKKLMQCLPNSNDVKMALEVYKLTLEIKQLQLQIDK-------AKH--VDREL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08607-1", "uniprot_id": "C4BPA_MOUSE", "id": "P08607-1", "name": "C4b-binding protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCAKQQQTLLPTRAAHGRLHRNRDAVAWPFSTLCRVSGPTLFQMTFTAALWVAVFGKCGP------------------------PPAIPNALPAS-DVNRTDFESHTTLKYECLPG-----------------------------------------------------------------------------------------------------YGRGISRMMVYCK----------------------------------------------------------------------PSGEWEISVSCAKKHCRNPGYLDNGYVNGET---------------------------------------------------------------------------ITFGSQIEFSCQEGFILVGSSTS----------------------------------------------------------SCEVRGKGVAWSNP----------------------------------------------------------------------FPECVIVKCGPPPDISNGKHSG-TEDFYP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YNHGISYTCDPG------FRLVGSPFIGCTVVNKTVPVWSSSPPTCEK------IICSQPNILHGV--IVSGYKATYTHRDSVR---------------------------------------------------------------------------------------------------------------------LACLNGTVLRGRHVIECQG----NGNWSSLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TCEFD---------------------------------------------------------CDLPPAIVNGYYT------SMVYS--KITLVTYECDKGYRLVG----------KAIISCSFSKWKGTAPQCKALCQKPEVGNG---------------------------------------------------------TLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASEDLKPAL-------TGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQK-------EKHTEAH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q60736-1", "uniprot_id": "ZP3R_MOUSE", "id": "Q60736-1", "name": "Zona pellucida sperm-binding protein 3 receptor", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MITWSFIDLWRTSHSTLFQMTLATVLMAPVLGDCGP------------------------PPLLPFASPTNQLYESTTFPSGTVLKYTCHHG-----------------------------------------------------------------------------------------------------FKRVNSS-HLSCD----------------------------------------------------------------------ENGSWVYSTFCARKRCKNPGELVNGKVEIPSD--------------------------------------------------------------------------LLVGSIIEFSCSKGYLLIGSATS----------------------------------------------------------RCEVQGKGVDWSDS----------------------------------------------------------------------LPECVIATCEPPPPISNGKHSGRDDDLYT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGSVVIYNCDPT------FTLLGNASIVCTVVNRTVGVWRPHPPACQK------IVCHRPQIPKGY--LAPGFRQFYAYRDALE---------------------------------------------------------------------------------------------------------------------IRCKKGFILRGSSVIHCEA----NGEWFPSIPTCEP-------------------------------------------------------------------------------------------------------------------NGCTNIPDISYASWEGYKFPLRNFEVFEIGAKLKYQCKPGYRASLNDPQT--------------------------------VTCQENLTWSSTNGCERICCPTPDMEKIKIVSERRDFTG-------------------------------------------------------------------------------------------------------------------------TCIYAYGDYVFYICNEGSYPMSTD------------GRSSCQAD---------------------------------------------------------GKWDPAIPSCQAD------SGLQN--RLALFTFPNISETNVTN----------KTYL--FGHEENSTEHAMKGVCLKPMVING---------------------------------------------------------NLSVERVIYAELENITIQCDPGYTIVGSPNIICSN-RTWYPEVPSCQMEVLEDCRIVS-------RGAQLLHCLSSPEDVHRALKVYKLFLEIERLEHQKEKWIQLHRKPQSMKINRSFRLCN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSY4-1", "uniprot_id": "ZP3R_RAT", "id": "Q7TSY4-1", "name": "Zona pellucida sperm-binding protein 3 receptor", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAWSLHELWKTSHSTLFQVTLATVLMAPVLGDCGP------------------------PPSLPFASPISQLDEVS-FPPGAVLKYTCHHG-----------------------------------------------------------------------------------------------------FKRTNSS-HITCD----------------------------------------------------------------------ENGSWVYTTFCARKRCKNPGELVNGKIEILSD--------------------------------------------------------------------------LLVGLNIEFSCSEGYLLIGSATS----------------------------------------------------------RCEVQGKGVNWSDS----------------------------------------------------------------------LPECVIATCEPPPVINNGKHSGREEDLYT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGSMVIYSCDPS------YTLFGNASIVCTVVNKTVGVWSPHPPACEK------IVCHQPQIPKGE--LVPGFRHFHTYKDALE---------------------------------------------------------------------------------------------------------------------IRCKKGFALRGNSVIHCEA----NGEWFPSVPTCEP-------------------------------------------------------------------------------------------------------------------NGCIDIPDISYASWDGNRFPLENTAVFEIGTKLKYRCKPGYRANVHDVQI--------------------------------VTCQENLTWSSPSGCERVCCPTPNMEKIKIVSERRDFTG-------------------------------------------------------------------------------------------------------------------------TCVYAYGDYVFYICSEGTYPMTTD------------GRSSCQAD---------------------------------------------------------GKWDPAIPSCEAD------PSLQN--HFAL-TFPNISETNVTN----------RTYL--LENE-NATESFIKAVCPKPEIING---------------------------------------------------------NLSVEKEIYAEMENITIQCDSGYDLVGSSNIICLENRTWYPDIPFCIMEGPEDCEIVN-------KGRQLLQCLSSPEDVQRALEVYKLSLEIERLEQQREKRTSVHRKAHYTKVDGPFRPFS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19070-1", "uniprot_id": "CR2_MOUSE", "id": "P19070-1", "name": "Complement receptor type 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTWFLFYFSEISCDPPPEVKNARKPYYSLPIVPGTVLRYTCSPSYRLIGEKAIFCISENQVHATWDKAPPICESVNKTISCSDPIVPGGFMNKGSKAPFRHGDSVTFTCKANFTMKGSKTVWCQANEMWGPTALPVCESDFPLE----------CPSLPTIHNGHHTGQHVDQFVAGLSVTYSCEPG-----------------------------------------------------------------------------------------------------YLLTGKKTIKCLS----------------------------------------------------------------------SGDWDGVIPTCKEAQCEHPGKFPNGQVKEPLS--------------------------------------------------------------------------LQVGTTVYFSCNEGYQLQGQPSS----------------------------------------------------------QCVIVEQKAIWTK-----------------------------------------------------------------------KPVCKEILCPPPPPVRNGSHTGSFSENVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGSTVTYTCDPSPEKGVSFTLIGEKTINCTTGSQKTGIWSGPAPYCVLS--TSAVLCLQPKIKRGQ--ILSILKDSYSYNDTVA---------------------------------------------------------------------------------------------------------------------FSCEPGFTLKGNRSIRCNA----HGTWEPPVPVCEKGCQAPPKIINGQKEDSYLLNFDPGTSIRYSCDPGYLLVG----EDTIHCTPEGKWTPITPQCTVAECKPVGPHLFKRPQNQFIRTAVNSSCDEGFQLSESAYQLCQGTIPWFIEIRLCKEITCPPPPVIHNGTHTWSSSEDVPYGTVVTYMCYPGPEEGVKFKLIGEQTIHCT------------------------SDSRGRGSWSSPAPLCKLSLPAVQCTDVHVENGVKLTDN-------------------------------------------------------------------------------------------------------------------------KAPYFYNDSVMFKCDDGYILSGSSQIRCKANNTWDPEKPLCKKEGCEPMR-VHGLPDDSHIKLVKRTCQNGYQLTGYTYEKCQNAENGTWFKKIEVCTVILCQPPPKIANGGHTG-----MMAKHFLYGNEVSYECDEGFYLLGEKSLQCVNDSKGHGSWSGPPPQCLQSSPLTHCPDPEVKHGY--------------------------------------------------------KLNKTHSAFSHNDIVHFVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRKASLGCQSPSTIPNGNHTGGSIARFPPGMSVMYSCYQGFLMAGEARLICTHEGTWSQPPPFCKEVNCSFPEDTNGIQKGFQPGKTYRFGATVTLECEDGYTLEGSPQSQCQDDSQWNPPLALCKYRRWSTIPLICGISVGSALIILMSVGFCMILKHRESNYYTKTRPKEGALHLETREVYSIDPYNPAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z9F7-1", "uniprot_id": "D3Z9F7_RAT", "id": "D3Z9F7-1", "name": "Complement component receptor 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGALGSLWVFFALIAPGVLGQCKLLPKYSFAKPTVVSDKSEFAVGTTWKYKCLPGYFRKSFTITCLESSKWSDAQQFCKRKPCMNPQEPLHGSVHINTGITFGSTITYSCNKGYRLIGDSSATCIISDNTVMWDNSVPICELIPCESPPAISNGYFQSSSRDSFFYGMVATYYCHVGKNREKLFDLVGEKSIYCTSKDNQVGIWNSPPPQCIARVKCPMPEIENGDVESGFKPSFFLNDTVMFKCKSGFIMKGSSIVWCQPDSKWSPPLPTCFRGCLPPQNILHGDYNEKDKEFFSVGQKVSYSCEPGYTLIGTNLVECTPLGAWSPSVPTCEVKSCDAIPNQLLNGRVLLPHNLQLGAEVSFVCDLGFQLKGKSSSQCVPEGETVIWNNKFPVCEQLSCDPPPEVNNTRRLYYSLPVLPGTVVRYTCLPGYRLIGEKAIFCISKDQVTATWDKATPICEPWNKMSACSKPIVPGGIINPGSRPPFKHGDSVTVTCKANFTMKGSKTVWCRANKMWGPTPLPVCESDFPLE----------CPSLPTIHNGHHTGQHVEKFVAGLSVTYSCEPG-----------------------------------------------------------------------------------------------------YLLVGKKTIKCLS----------------------------------------------------------------------SGAWDDVIPTCKEAKCERPEKLPNGQVKEPPS--------------------------------------------------------------------------LRVGTTVYFSCNEGYELQGQPSS----------------------------------------------------------KCVIVEQKAVWTK-----------------------------------------------------------------------KPVCKEILCPPPPPVLNGRHSGRFSGNVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGNNVTYMCDPSPEKGVNFTLIGEKTIYCTNSSEKTGIWSGPAPYCKLS--ISEAQCLRPQINRGQ--ILSILKESYSYNDTVA---------------------------------------------------------------------------------------------------------------------FSCEPGFTLKGSGRIRCSA----QGTWKPPVPVCEKGCQAPPKIINGQKEDRYFLNFDPGTSIRYSCDPGYFLVG----EDTIHCTSEGKWTPIPPQCKVAECKPVGPHVFERPQNHFIRPAINSSCDEGFQISESAYQLCQGTIPWFIEIRLCKEITCPPPPIILNGTHTWRSSEDVPYGTVITYMCYPGSEEGVKFKLIGEQTIHCT------------------------SDSRGRGSWSSPAPLCKLSLPAVQCTEVHVENGVKLTDN-------------------------------------------------------------------------------------------------------------------------KAPYFYNNSVTFKCRDGYILIGSSQIRCKANNTWDPEAPHCKKEGCEPMRKLPGISDHSLIKLVNRTCQNGYQLTGYTYEKCQNAENGTWFQKIAVCTVILCPPPPTIANGSHTG-----MMAEHFLYGNEVSYECDKGFYLLGEKSLQCK----GHGSWSGPPPQCLQSSPLTHCPDPEVKYGY--------------------------------------------------------KLNKTHSAYSHNDIIHVVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRTASLGCQSPPTIPNGNHTGGTIARFSPGMSVMYSCYQGYLMAGEARLICTHEGTWSHPAPYCKEVNCSFPEDTNGIQKGFQPGKTYRFGTTVTLECEDGYSLEGSPQSQCQDENQWNPPLAICKNR--STVPLVSGISAGSAFIILISVIFFIILKSRERNYYTKTRPKDGALHLETREVYAVDPYNPAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61476-1", "uniprot_id": "DAF2_MOUSE", "id": "Q61476-1", "name": "Complement decay-accelerating factor transmembrane isoform", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSSTWGYDPRAGAGDLVITTTAAGAVTIAVLLFQ-TVCGDCGP--------------------------PPDIPNARPILGRHSKFAEQSKVAYSCNNG----------------------------------------------------------------------------------------------------FKQVPDKSNIVVCLE----------------------------------------------------------------------NGQWSSHETFCEKSCDTPERLSFASLKKEYFNMN----------------------------------------------------------------------FFPVGTIVEYECRPGFRKQPSLSGK--------------------------------------------------------STCLEDLVWSPVAQF-------------------------------------------------------------------------CKKKSCPNPKDLDNGHINIPTGILFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEINFSCNPG------YRLVGITSILCTIIG-NTVDWDDEFPVCTE------IFCPDPPKINNG--IMRGESDSYKYSQVVI---------------------------------------------------------------------------------------------------------------------YSCDKGFILFGNSTIYCTVSKSDVGQWSSPPPQCIEESKVPIKKP--------------------------------------------------------------------------------------------------------------------------------------------VVNVPSTGIPSTPQKP----------------------------------------TTESVPNPGDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTPQKPSTVKVP-----------------------------------------------------------------------------------------------------------------------------------------------ATQHEPDTTT------RTSTDKGESNSGGDRYIYGFVAVIAMID-------------------------------SLIIVKTLWTILSPNRRSDFQGKERKDVSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61475-1", "uniprot_id": "DAF1_MOUSE", "id": "Q61475-1", "name": "Complement decay-accelerating factor, GPI-anchored", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIR---GRAPRTRP---SPPPPLLPLLSLSLLLLSPTVRGDCGP--------------------------PPDIPNARPILGRHSKFAEQSKVAYSCNNG----------------------------------------------------------------------------------------------------FKQVPDKSNIVVCLE----------------------------------------------------------------------NGQWSSHETFCEKSCVAPERLSFASLKKEYLNMN----------------------------------------------------------------------FFPVGTIVEYECRPGFRKQPPLPGK--------------------------------------------------------ATCLEDLVWSPVAQF-------------------------------------------------------------------------CKKKSCPNPKDLDNGHINIPTGILFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEINFSCNPG------YRLVGVSSTFCSVTG-NTVDWDDEFPVCTE------IHCPEPPKINNG--IMRGESDSYTYSQVVT---------------------------------------------------------------------------------------------------------------------YSCDKGFILVGNASIYCTVSKSDVGQWSSPPPRCIEKSKVPTKKP--------------------------------------------------------------------------------------------------------------------------------------------TINVPSTGTPSTPQKP----------------------------------------TTESVPNPGDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTPQKPSTVKVS-----------------------------------------------------------------------------------------------------------------------------------------------ATQHVPVTKTTVRHPIRTSTDKGEPNTGGDRYIYGHTCLITLT--------------------------------VLHVMLSLIGYLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5XWT0-1", "uniprot_id": "A0A8I5XWT0_RAT", "id": "A0A8I5XWT0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIR---TRAPGTRAP---PPPPLLLSLSLLLLLLSPTVSGDCGP--------------------------PPDIPNATPNSGKHTKFAHQSQVTYSCNKG----------------------------------------------------------------------------------------------------FKQIPDKPNTVVCLE----------------------------------------------------------------------NDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMN----------------------------------------------------------------------FFPIGTTVEFECRPGFQKVTSRTGK--------------------------------------------------------STCLEELVWSPVVEF-------------------------------------------------------------------------CKKRACPNPRELKNGHINIPTDILFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEIIFSCDKG------YKLVGVTSTFCSITG-NAVDWDDVFPVCTT------IFCPDPPKINNG--RIREESDSYAYRQSVT---------------------------------------------------------------------------------------------------------------------YSCDQGFILVGNSSVHCTLN-GEVGEWSSAPPKCIERHKVPTKTPP----------------------------------------------------------------------------EVDIPSTMPHESTLINFPSTRAPLSHKPTTVKVPGTRVKPTSHKPTEVKVPGTRVPPTSQKHTTVNVPSTRVPATSQKPSMVHVSDTRVSPKPQKPTKANNPSTEIPPTPQKANTADVPSTESPPTPQKANTAVVPATEIPPAPQKTNTAVAPATEIPPTPQKTNTADVPSTESPPTPQKANTADVPATEIPPALQKANTAVVP-------------------------------------------ATETLPTPQKANTAIVPATETPPAPQKTNTAVAPSTEIPPTPQKANTADVPATEIPPTPQNANTADVPSTEIPPTPQKSNTADVPATEIPPTPQKANTADVPATEIPPTPQNANTADVPSTEIPPTPQKTNTAKVSAIKPATAQMSLISTTVFAQTPPITQHPTTVNSSAVQTAQTTRGFATAKPSLTQNPPATQRPTISHFSMTKGLH----------------------------------------------------------TVTQIFTSAHITATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGHTCLITMT--------------------------------ILHVMLLLTG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08174-1", "uniprot_id": "DAF_HUMAN", "id": "P08174-1", "name": "Complement decay-accelerating factor", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGL--------------------------PPDVPNAQPALEGRTSFPEDTVITYKCEES----------------------------------------------------------------------------------------------------FVKIPGEKDSVICLK----------------------------------------------------------------------GSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQN----------------------------------------------------------------------YFPVGTVVEYECRPGYRREPSLSPK--------------------------------------------------------LTCLQNLKWSTAVEF-------------------------------------------------------------------------CKKKSCPNPGEIRNGQIDVPGGILFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATISFSCNTG------YKLFGSTSSFCLISG-SSVQWSDPLPECRE------IYCPAPPQIDNG--IIQGERDHYGYRQSVT---------------------------------------------------------------------------------------------------------------------YACNKGFTMIGEHSIYCTVN-NDEGEWSGPPPECRGKS-LTSKVP------------------------------------------------------------------------------------------------------------------------------------------------PTVQKPTTVNVP----------------------------------------TTEVSPTSQKT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTKTTTPNAQ-----------------------------------------------------------------------------------------------------------------------------------------------ATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTG---------------------------------LLGTLVTMGLLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6F5-1", "uniprot_id": "A0A8M3B6F5_DANRE", "id": "A0A8M3B6F5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVWRNALVLVFVHLVVSQTRFRCGEPPKYPDKQLDIKYIYRPVFNHQDKVSYRCHRGHVPSEGNRMSFCMRGRWTPLTLKCQKVKCNGLADIKNGQYRREGQSYGDKAIVICNQGYVLKGVKFRMCLEKGWSGTDPVCLAPQVT--------------CSAPTVENRWIKPGERTQYTTQDTVSITCSEG------------------------------------------------------------------------------------------------------FDLIGSSVVTCGP----------------------------------------------------------------------NGQWRDLPECHRKVPKMTCPAPAVENRSIKPGER---------------------------------------------------------------------TQYTPQDTVSITCSEGFDLIGSSLVT----------------------------------------------------------CGPDGQWQNLPKCHR------------------------------------------------------------------------KVILCSAP-AVANGRINAFGNQHKP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDTVSITCSEG------FELIGSPQVTCGP----DGQWQS-LPECHPKRRSANVIFCSAPVVANG--RINAFGNQHKPKDTVS---------------------------------------------------------------------------------------------------------------------ITCSEGFELIGSSQVTCGP----DGQWQGLPECHPKKHLVNVN--------------------------------------------------------------------------------------------------------------------LCSAPAVANGRINEFGNTFKPKDTVSIICSEGFDLIGSPQVTCG------------------------------PDGQ----WQSLPECHPKTRLANGKCGPPPSYLHHNVFFREG-------------------------------------------------------------------------------------------------------------------TPSLTEYSSGARIRYKCNLGLRRASGSDIIRCQAGEWTKLALRCQRK--------------------------------------------------------SCGSAGEISFGRFQYSG--------VLFGDSARAICQEGYELIGPE---------ERVCRDGGWDGRIPVCEPVYCPPPPEVKDAEVS-------------------------------------------------------DFRNEDVPVGHMVSYRCQTG-ALIGTQDLYCTTNGTWSGPAPLCKDISCPRPDIPRG----------------------SRMRGFRSVYKYGNTVTIACSPGLRLYGESFVTCGADGNWTPKLPECRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A3V1-1", "uniprot_id": "A0AB13A3V1_DANRE", "id": "A0AB13A3V1-1", "name": "Beta-2-glycoprotein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERSLLVAFVCVWALSS--------------------------------------LSAASEDAAEQCPERILGNERRQTCPKKCQQ-----------------------------------------------------------------------------------------------------DKDCGNKRQCLCD------------------------------------------------------------------------GQCGLSCVVPGRMCPWPLPLGKHSDIVLLSPSP------------------------------------------------------------------------SFSALLEVRCKSGYTLSNGLDTTIR-------------------------------------------------------RCQGDRQWSGDEPVCS-------------------------------------------------------------------APPGGDVSAGPGLVPDVSCSLPEDDDLLSVQG--------------------------------------------------------------------------------------------------------------------------------------------------------------------SATTGSTIKYRCASG------SVLIGNSENICHEN----QTWQYPHPICRR------VVCPPPKEVADRGHLVAVQRTEYDVGDTIY---------------------------------------------------------------------------------------------------------------------YLCKKTFLLDGPNQVTCLP----NGTWSAEPACRAR---------------------------------------------------------------------------------------------------------------------------------------------------CPVPAQRSRVIVGGVKR-----------------------------------------WPYDLTDG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVAHGENVTFFCKHPEKLCSFTATEVCVDG--ELKAPSCYLDPTWLQFKLYP---------------------------HRLVSEIDACDRADLQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B906-1", "uniprot_id": "A0A8M2B906_DANRE", "id": "A0A8M2B906-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRNVLSLAVALFSCLLMCTHVQGECTLP-----------------------SFESRNVVLSGSYSPGQTLPDGSALTFECLSGHT---------------------------------------------------------------------------------------------------PVDSRATKSITCTK----------------------------------------------------------------------SQWTDLGLSCKKKSCGSPPEIVNGRYEISG---------------------------------------------------------------------------ILFGDTIKPICNTGYMLVGYGLDQ---------------------------------------------------------RVCRDGGWDGRDPE-------------------------------------------------------------------------CEVVKCAAPPSIENGQLSDEPLESYE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSQVVTYRCNSG------FSLSGSSNLHCSD----DGTFKPDPPKCLDG-------CPKPEIPHAIR--IGGRSPPYKIGHFIE---------------------------------------------------------------------------------------------------------------------YKCEDLYTLKGIKEIACRA-----GGWDPEPPKCIEPCRVPNFGG-----------------------------------------------------------------------------------------------------------------------NVTLREEFSSKDLFPHGDKVAFKCKSGYEPVDSTVSR--------------------------------IATCEETKWTKLLLTCKASPTTTT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TARAPTTARTPTS----------------------------------------------------------------------------------------------------------------------------------------HTTSKVLPDGDEEKSSSSSAPLGAILGGIFGSGGLLLLGCFGVYMLVTK-------------------------------QSKRKQKVPTNEEGSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYR4-1", "uniprot_id": "Q9VYR4_DROME", "id": "Q9VYR4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFCCNIPVDASVATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGPPAVPLNAKVRTITVDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVHVVRITTRGCCGHQPLQDLEIRVGNSSADLQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPN-------------NYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLS---------------------------------------------------------------------------------------------CGSPDAQQNTTVMGKKFTLG----------------------------------------------------------EKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFG---------------------------------------------------------SIHMSEERTSFGVVATYSCHENYTLIGNENR----------------------------------------------------------TCAMDGWSGKQPE--------------------------------------------------------------------------CLVDWCPDPQPIAGGDVRFNDKRAGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------TATYVCEPG------YVLVGEAIISCGLG----GEWSSKTPSCRF------VDCGAPARPNRG--IAILLNGTTTVNSVVK---------------------------------------------------------------------------------------------------------------------YECDEDHWLDGQSELYCTR----EGKWSGEAPVCELVTCETPSVPSGS-------------------------------------------------------------FVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTN--TTYVGSEVVFSCSQSHKLSGVLKRTCLES----------------------------------AVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYG---------------------------------------------------------------------------------------------------------RTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEG----INNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGND--------TRVCQKNGKWTGKSPTCRPVDCGRPLAIENG--------------------------------------------------------RVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * : . * * * * ", "identical_positions": 7, "similar_positions": 2, "identity": "0.18%" }, { "cls_id": "homologset.agr.FB:FBgn0001084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B756-1", "uniprot_id": "FUZZY_RAT", "id": "Q3B756-1", "name": "Protein fuzzy homolog", "aln": "MGDDGPGSTVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSART--------------EDTTVVWKNFHDSITLIALSSEEGTSELKLERMLHMVFGAMVLIVG-LEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQETLSGFAEATGTAFVSLLVSGRVVAATDGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPR-PPLGELDPQLLERWWQPLLEPLRACLPLGPRALPDGFPLHSDILGLLLLHLELRRCLFTVEPSKDKEPS-----PEQRRRLLRNFY--TLVATTHFPPEPGPAEKQEDTVHPAQTPRACYLVLG---PGMGWQLVAVQLGLRLLLLMLSPQTPTHGLRSLATHTLQALTPLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UYI6-1", "uniprot_id": "FUZZY_MOUSE", "id": "Q3UYI6-1", "name": "Protein fuzzy homolog", "aln": "MGDEGPGSPVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSART--------------EDTTVVWKNFHDSITLIVLSSEEGTSELRLERMLHMVFGAMVLIVG-LEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSAMQETLSGFAEATGTAFVSLLVSGRVVAATEGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPR-PPLGQLDPQLMERWWQPLLEPLRACLPLGPRALPEGFPLHSDILGLLLLHLELRRCLFTMEPSKDKEPS-----PEQRRRLLRNFY--TLVATTHFPPEPGPAEKQEDTVYPAQMPRACYLVLG---PGMGWQLVAVQLGLRLLLLLLSPHTPTHGLRSLATRTLQALTPLL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT04-1", "uniprot_id": "FUZZY_HUMAN", "id": "Q9BT04-1", "name": "Protein fuzzy homolog", "aln": "MGEEGTGGTVHLLCLAASSGVPLFCRSSRGGAPARQQLPFSVIGSLNGVHMFGQNLEVQLSSART--------------ENTTVVWKSFHDSITLIVLSSEVGISELRLERLLQMVFGAMVLLVG-LEELTNIRNVERLKKDLRASYCLIDSFLGDSELIGDLTQCVDCVIPPEGSLLQEALSGFAEAAGTTFVSLVVSGRVVAATEGWWRLGTPEAVLLPWLVGSLPPQTARDYPVYLPHGSPTVPHRLLTLTLLPSLELCLLCGPS-PPLSQLYPQLLERWWQPLLDPLRACLPLGPRALPSGFPLHTDILGLLLLHLELKRCLFTVEPLGDKEPS-----PEQRRRLLRNFY--TLVTSTHFPPEPGPPEKTEDEVYQAQLPRACYLVLGTEEPGTGVRLVALQLGLRRLLLLLSPQSPTHGLRSLATHTLHALTPLL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16868-1", "uniprot_id": "FUZZY_DROME", "id": "O16868-1", "name": "Protein fuzzy", "aln": "-------MSIYLLCLTTNGGLPVFTRKKG----ECENLPFSTVASLNGFHMFFKSLGIQLEATTTSKQQPIQNQAPADAEEWTYIWR-DRESITLIVCGCGVGS-EQLLQTLADLVFGAIGMFITRAAEMAHATLLDRLKKDAKKYVPIVDAILEAACAGTQLLGYTDCLLAAENAQLLQCLNEFSGHCGSLFCCLVVGHRIAVATEGWWDLDTRDRELLLFLLNSSS-TMQHDVPVYLPVKSPHIAYRFVSIPVASNSALCVLCGAENASFRELHAHAMSAYRN-EGNLLAAAERCVPRSLPEHLEIDGNVLAIILINRHTRKSLFTRNLNQSASVKRIIVGDLQRLDILKKFFDQTMDAVHQFETQSSSNKTTLVDQYSCSDYHKCYAHMD-------------ELGN-VIFLLFVAAVPSHAMRFLAQRIHANILQEKSVCW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::****::..*:*:* *.. ::****.:.****.*** :.* :**.:: * *: * :*: ::*****. .. * * *: : .:****: ::: *::: ::****: : ::*::* : :* .**::..*.: : : *. *: *: * .*:*. *:..**:*** *. : ** :*:.* . :* ***** ** :.:*::::.: . **:***. ..: :* .: :. : : : * *. **:**. : :. ::*.::*:: . ::.*** : . . . ** :*::*: *: : :* .:... :. : .. : ** :. :** ::*:: . *:*.:* ** : : ", "identical_positions": 108, "similar_positions": 153, "identity": "24.27%" }, { "cls_id": "homologset.agr.FB:FBgn0001085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACM8-1", "uniprot_id": "D4ACM8_RAT", "id": "D4ACM8-1", "name": "", "aln": "----------------------------------------MRGPGTEASHSPLGLCALVLALLGALP---------------TDTG------------AQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSG-GAGGSPTAYPTAPYLPDPPFTAMSP--SDGRGR---WSFPFSCPRQLKVPPYLGYRFLGE----RDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSD-------DGYRTVAQGTKKE-GCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCP-------PGHFSPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHS---SKGETAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61090-1", "uniprot_id": "FZD7_MOUSE", "id": "Q61090-1", "name": "Frizzled-7", "aln": "----------------------------------------MRGPGTAASHSPLGLCALVLALLGALP---------------TDTR------------AQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSG-GAGGSPTAYPTAPYLPDPPFTAMSP--SDGRGR---LSFPFSCPRQLKVPPYLGYRFLGE----RDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSD-------DGYRTVAQGTKKE-GCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCP-------PGHFSPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHS---SKGETAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75084-1", "uniprot_id": "FZD7_HUMAN", "id": "O75084-1", "name": "Frizzled-7", "aln": "----------------------------------------MRDPGAAAPLSSLGLCALVLALLGALS---------------AGAG------------AQPYHGEKGISVPDHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSG-GPGGGPTAYPTAPYLPDLPFTALPPGASDGRGR---PAFPFSCPRQLKVPPYLGYRFLGE----RDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSD-------DGYRTVAQGTKKE-GCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCP-------PGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHS---SKGETAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08464-1", "uniprot_id": "FZD2_RAT", "id": "Q08464-1", "name": "Frizzled-2", "aln": "----------------------------------------MRARSALPRSALPRLLLPLLLLPA------------------AGP--------------AQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDG--TPALLTTAPPSGLQPGAGGTPGG-PGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGE----RDCAAPCEPARPDGSMFFSHHHTRFARLWILTWSVLCCASTFFTVTTSLVAMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSE-------DGYRTVGQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHAAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNRLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEPLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCP-------AHYTPRTSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNS---RHGETTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIP6-1", "uniprot_id": "FZD2_MOUSE", "id": "Q9JIP6-1", "name": "Frizzled-2", "aln": "----------------------------------------MRARSALPRSALPRLLLPLLLLPA------------------AGP--------------AQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDG--APALLTTAPPSGLQPGAGGTPGG-PGGGGSPPRYATLEHPFHCPRVLKVPSYLSYKFLGE----RDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSE-------DGYRTVVQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCP-------AHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNS---RHGETTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14332-1", "uniprot_id": "FZD2_HUMAN", "id": "Q14332-1", "name": "Frizzled-2", "aln": "----------------------------------------MR-----PRSALPRLLLPLLLLPA------------------AGP--------------AQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDG--APALLTTAPPPGLQPGAGGTPGG-PGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGE----RDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSE-------DGYRTVVQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCP-------AHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNS---RHGETTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08463-1", "uniprot_id": "FZD1_RAT", "id": "Q08463-1", "name": "Frizzled-1", "aln": "MAEEAVPSESRAAGR-PSLELCAVALPGRREEVGHQDTAGHRRPRAHSRCWARGLLLLLWLLEAPLLLGVRAQPAG----QVSGPGQQRPPPPQPQQGGQQYNGERGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERA-QGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGPVER-----GKFSCPRALRVPSYLNYHFLGE----KDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAE-------DGARTVAQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNS---KQGETTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70421-1", "uniprot_id": "FZD1_MOUSE", "id": "O70421-1", "name": "Frizzled-1", "aln": "MAEEAAPSESRAAGR-LSLELCAEALPGRREEVGHEDTASHRRPRADPRRWASGLLLLLWLLEAPLLLGVRAQAAG----QVSGPGQQAPPPPQPQQSGQQYNGERGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGTVER-----GKFSCPRALRVPSYLNYHFLGE----KDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAE-------DGARTVAQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNS---KQGETTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP38-1", "uniprot_id": "FZD1_HUMAN", "id": "Q9UP38-1", "name": "Frizzled-1", "aln": "MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLWLLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASER-----GKFSCPRALKVPSYLNYHFLGE----KDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAE-------DGARTVAQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNS---KQGETTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18537-1", "uniprot_id": "FRIZ_DROME", "id": "P18537-1", "name": "Frizzled", "aln": "---------------------------------------MWRQILFILPTLIQGVQRYDQSPLDASPYYR------------SGGG------------LMASSGTELDGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLCESA-RVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTG--------VESPHR----NIGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCH------AMFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAAR----APGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .. * . .:*.*. *:**:*.:*.:*.** **:***:***:**:******** ****: ** :*::****:*.****:*::.:*****:** * : ** **:.:.*:**: *.*.:** **. ::**.:* :. . . * * ** *:.* :.*.: :**.***. *:* .. . * *: *:.:* ** :*** * *: ** ****.*:**: ** *. *::**: : . * : *. : *: ** :: .**:*** *** **: ** *:::******:**** *** :*: ***.******::**::**:.:::**:*****:** ..* .*:: ** :** **: ******:*******:** **.:*: **:**:***.** *: :**. ::.* *** :.* * : **. ::*** . * * ::*:*** :::**:*:..*::*.**: ***.* ** . :.:: *", "identical_positions": 234, "similar_positions": 153, "identity": "35.08%" }, { "cls_id": "homologset.agr.FB:FBgn0001087", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFK6-1", "uniprot_id": "B5DFK6_RAT", "id": "B5DFK6-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEGAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAK------------------GVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPP-----SDSESEDEKPKAIFHEEEP------RHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKE----KGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPVQKHRNAETVKSPEKEG-----VPGVEKKSKKPKKKEKKPKERERE--KKDKKGE-------------------------------------DLDFWLSTTPPPAAAPVPAPSTEGLAASIVTPPKGECEVLKGEEPQDEEDHMDHDQERKSSRHKKKKHRKEKE--ERPRDKKKAKRKQVVQLEN-GAPAEEEEEE-EEPIPPMSSYCLLAENPYIKVT-------YDVQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMARPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISISFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLSQC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54774-1", "uniprot_id": "AP3D1_MOUSE", "id": "O54774-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAK------------------GVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPP-----SDSESEDEKPKAIFHEEEP------RHTRRRQPEEDEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEQRRHRQRLEKDKKRKKKE----KGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPVQKHRNAEAVKSPEKEG-----VLGVEKKSKKPKKKEKKTKERERE--KKDKKGE-------------------------------------DLDFWLSTTPPPAAAPIPAPSTEELAASTITSPKDECEVLKGEE----EDHVDHDQERKSSRHKKKKHRKEKEKEERPRDKKKAKKKQVAPLEN-GAAAEEE----EEPIPPMSSYCLLAESPYIKVT-------YDIQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMTRPEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISMSFQNLLAKICFYHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLAQC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14617-1", "uniprot_id": "AP3D1_HUMAN", "id": "O14617-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKMVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG----TRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAK------------------DVPVAEEVSALFAG-ELNPVAPKAQKKVPVPEGLDLDAWINEPL-----SDSESEDERPRAVFHEEEQ------RRPKHRPSEADEEELARRREARKQEQANNPFYIKSSPSPQ--KRYQDTPGVEHIPVVQIDLSVP----LKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKD----PNDPYRALDIDLD--------KPLADSEKLPIQKHRNTETSKSPEKD------VPMVEKKSKKPKKKEKKHKEKERD--KEKKK--------------------------------------------------------------------------------------------EKEKKKSPKPKKKKHRKEKE--ERTKGKKKSKKQPPGSEEAAGEPVQNGAPE-EEQLPPESSYSLLAENSYVKMT-------CDIRGSLQEDSQVTVAIVLENRSSSILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLKGTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIRMSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTLLSNLLEEMKATLAKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AM99-1", "uniprot_id": "A0A8M3AM99_DANRE", "id": "A0A8M3AM99-1", "name": "AP-3 complex subunit delta-1", "aln": "--------MALKIVKG-SIDRMFDKNLQDLVRGIRNH---KEDEAKYISTCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDVSWAAFNIVEVMSSSKFTYKRIGYLAASQCFHEGTDVIMLTTNQIRKDLSSPNQ---YDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMLHVDKAEG---------------------TTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEG----TRHGHLIASQMLDVAIRVKAIRAFAVAQMATLLDNAHLLTGNTQRNGICEVLYAAAWICGEFAEHLEDPMLTLEAMLRPKVATLPGHIQAVYVQNAAKLFATVLQKHEGETDSQAAQETSQLLIDRLPLFVQSANLEVQERASCILQLVKYIQKLQQK------------------NVEVAEEVTALFAG-ELNPVAPKAQKKVPIPEGLDLDAWINEPP-----SESESEDEKPKAVFAKEEP------KHSRSRHTEVDEKELARRREARKQEQANNPFYIKASPSSQ--KVY-DAPGVEHIPVVQIDLSVP----LKVPGMPMSDQYVKLEEERRQKEKADKKKKEKKKK-REKRGKGRKGDSGPESEEDITPAHHVDIVTEEMPENALPSDDDDKD----PNDPHKALDIDLDNLLSGAGSRPLADSEKLPVRTHR-PEVLKSPAEDRDDNTIPQETKKKSSKDKKEKKKDKEKDRKRSKEDKKKKKKHKDVEEELPESLPEEVVQSEETKEVAVPPTSADASDLDFWLSSAPVPPVAQVVTVSSSAAAATVDSSSAAAAESEPEE------LKDTEPDDTKSSKHKKKKQKKEKEEKEKKKKKRHHHHHHHHSDAGAEDSVQNGTVEDEEPLPPMSNYSLLAENSYIKMMKEDADQVCDIQGNHQDESKVVVSVIFENKSDSFLKSMEFNVLDSLNSKLQRPDGAGPHDGLTVPFQLPPGVSNEARFVFSVQSIVMPQKLKGTLTFIVKTDESSTHEKLDFKLHFTCTSYLITTPCYSDAYAKLLESGDLKGSSLRLEGVNMPFHHLLARICFHHHFSVVERIDSCASMYSRSIQGHHVCLLVKSSDQTVSIDAKCDEPSLLGNVLDEIKQTFSKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54362-1", "uniprot_id": "AP3D_DROME", "id": "P54362-1", "name": "AP-3 complex subunit delta", "aln": "--------MALKKVKGNFFERMFDKNLTDLVRGIRNN---KDNEAKYISTCIEEIKQELRQDNISVKCNAVAKLTYIQMLGYDISWAGFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLNSQNQ---YDAGVALSGLSCFISPDLSRDLANDIMTLMSSTKPYLRMKAVLMMYKVFLRYPEALRPAFPKLKEKLEDPDPGVQSAAVNVICELARKNPKNYLPLAPIFFKLMTTSTNNWMLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECINTVIAVLISISSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQAHKDLILACLDDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEG---------------------SAYRDELLYKVIEICAQSSYLYVTNFEWYLTVLVELIQLEAG---SRHGRLIAEQLLDVAIRVPVVRQFAVNEMTNLLD---TFTVSAQSNSMYEVLYAAAWIVGEFAGELEDAEKTLNILLRPRL--LPGHIQGVYVQNVIKLFARLATTCLELQDLPGLVTLCDHVLDKLQHFNGSSDIEVQERANSACMLIEMLRNQLSTSTDAMAMDTTTEGGIPPLAIEIVQEMTLLFTG-ELIPVAPKAQRKVPLPDGLDLDEWINAPPPEDAASSSSSEHDKDELFVSATQAGTGADGGEKRRQSLELTPEQLERQRMARLIEQSNNPHYLKSTPTASGASNADQYDNIDDIPITELPLDMEGVAALRVGITKRSDKYLQEQQAAQGSKDGKKKHKKGKKS---KKAKNKVAYNSSSESEGEPKPLHIVNTTLDMPEGVSMSDSEDKDGKYDPNDPHRALDIELD----------ITEFEAPAVRSASKKSAADKENLKT-----PADLAGGGNAAKKDRKKDKDKDKE-----------------------------------------------------------------------------------------------------------RKVKREHR------ESKRERKEAAVQPVIDLIDADTPTPSP--------------SHISAT---------------------SNNNNTSTVLPDAPKHHKKKKNKEKTTDEAPDALATATGSSIID-----------VGGEE--ASEVASKVHKKKHK--------KEKSQRKEKK--------------KASESASVSAIVSIGDYEQP----LGISTPSKEIL--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08951-1", "uniprot_id": "AP3D_YEAST", "id": "Q08951-1", "name": "AP-3 complex subunit delta", "aln": "MTSLYAPGAEDIRQRLRPFGFFFEKSLKDLIKGIRSHNETPEKLDQFFKQVLSECREEVNSPDLNSKTNAVLKLTYLEMYGFDMAWCNFHILEVMSSNKLQQKRVGYLAASQSFYKDSDILMLATNLLKKDLKYDGNNDVVKVGIALSGLSTIITPSLARDIADDLFTMLNSTRPYIRKKAITALFKVFLQYPEALRDNFDKFVSKLDDDDISVVSAAVSVICELSKKNPQPFIQLSPLLYEILVTIDNNWIIIRLLKLFTNLSQVEPKLRAKLLPKILELMESTVATSVIYESVNCIVKGNMLEED----DFETAMACLERLHTFCDSQDPNLRYISCILFYKIGKINTDFISRFDQLIIRLLSDVDVSIRSKAIELVEGIVDEDNLKAIVQTLMKQFVDEDVVILQTGSIVYEKSKRIPIIIPENYKIKMVNVIISICSADNYSSVNDFEWYNAVIMDLAMLCQDISDKSLGSKIGEQFRNLMIKVPSMREVTIANIIKLIS------NDNINKQLPTVLRECIWCLGEFSTLVENGN-DLIKIMTENISYYSHSVQEVLILALVKVFSNWCNN-FQEDKRFEIKMVLKELIEFFENLSYSSTFEVQERSVEVLEFLRLSLEALEEDTEG-------------LPMLLSEVLPSFFNAYELAPIARGTQLKLAVDENLDLETPFLTKEA----ADELLDEQKSDAISDLMSD-----ISMDEQVELKFVDDSDTSYEEKEKLDDFENPFEIEREKERMSNPYYLGEEDEERT--------------------KNSKDLLDLNEEESSDKKPETIRLNRTDN-----SLNSLSLSTTEISRKKKKGKKKNRVQVLSDEPVIEAAPKRKDAFQKPHDNHSTQNPLKK--------------DKINLRMHSQLENFDFSNFGQ------SSNAGRGSQEEGNLRKEDELELS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLEANLIVKDEKDNLSDTEEVIVIKKKKKGKKSKSKN----------------------------------------------------------------KLKTKAKNSPEPNEFLRDQSTDI------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:*.* **::***.: :. :::. :.* ::*:.. :: * *** ****::* *:*::*. *:*:****:.:: **:*******.*: .::::**:** ::***. .: ..*:**:*** :::*.*:**:*:*::*::. *:**:* **: ::****:***:** * :: .**:* * .* ****.*****:::**: :: *:*::::::.: ***::*:::*** *: :**:* **: : :*:.** * *::**.:* :: : .. . : *:::*: : :..* **:*:. : : ** * :.. :. ..:**: *.* * *** :*::*: *:*.:.** **: *: :. : *: ::: :*.**: ..* :.:**** :::::* * . * *. *: :: *:* :* .:: :: *:. . : : ** . * ***: :: * :: .: . :* * : *::: . . ::: : : *: :*****: ::. : : : : :. :* . ** *:* :* *:.: :.***: : :.. :.:: . . . : .. . . :: :**. :: . : *.. :. :: : .. : . . . . . .. .. : * . : . ** *:* : : : . : :: . . .. : . :* .: : . . :: . . . : . .. .. * :: . . ", "identical_positions": 193, "similar_positions": 313, "identity": "14.29%" }, { "cls_id": "homologset.agr.FB:FBgn0001089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUM4-1", "uniprot_id": "D3ZUM4_RAT", "id": "D3ZUM4-1", "name": "Beta-galactosidase", "aln": "--------MFRVPLCMLLPLLALLQLLGAAHSFYNVSQR-----TFELDYKRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLDAIQTYVPWNFHEPQPGQYDFSGDRDVEHFIQLAHQLGLLVILRPGPYICAEWDMGGLPAWLLEK-ESIVLRSSDPDYLAAVDKWLAVLLPKMKRLLYQNGGPIITVQVENEYGSYFACDYNYLRFLEHRFRYHLGNDIILFTTDGAAEKLLKCGTLQDLYATVDFGTT--GNITRAFLIQRNFEPKGPLINSEFYTGWLDHWGQPHSKVNTKKLVASLYNLLAYGASVNLYMFIGGTNFAYWNGANMP------YAPQPTSYDYDAPLSEAGDLTEKYFAVRDVIRKFKEVPEGPIPPSTPKFAYGKVALRKFKTVTEALG--ILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPINGVRDRAYVSVDGVPQGILDRN-RMNVLNIRGKAGATLDILVENMGRVNYGNSIKDFKGLISNMTLNFT-----VLTNWTMFPLDTEALARSHLGNWEAADEGHLDGHSTLRSSNFTLPTFYVGNFSIPSGIPDLPQDTFIQFPGWAKGQVWINGFNLGRYWPTKGPQMTLFVPRNILTTS-APNNITVLELESSPCSNGTLELCTVEFVDTPVIG----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23780-1", "uniprot_id": "BGAL_MOUSE", "id": "P23780-1", "name": "Beta-galactosidase", "aln": "--------MLRVPLCTPLPLLALLQLLGAAHGIYNVTQR-----TFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEK-QSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYFACDYDYLRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQDLYATVDFGTG--NNITQAFLVQRKFEPKGPLINSEFYTGWLDHWGKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANTP------YEPQPTSYDYDAPLSEAGDLTKKYFALREVIQMFKEVPEGPIPPSTPKFAYGKVALRKFKTVAEALG--ILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPFNGVRDRAYVSVDGVPQGILDRN-LMTALNIRGKAGATLDILVENMGRVNYGRFINDFKGLISNMTINST-----VLTNWTVFPLNTEAMVRNHLWGREASDEGHLDGRSTSNSSDLILPTFYVGNFSIPSGIPDLPQDTFIQFPGWSKGQVWINGFNLGRYWPTMGPQKTLFVPRNILTTS-APNNITVLELEFAPCSEGTPELCTVEFVDTPVIS----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16278-1", "uniprot_id": "BGAL_HUMAN", "id": "P16278-1", "name": "Beta-galactosidase", "aln": "---------MPGFLVRILPLLLVLLLLGPTRGLRNATQR-----MFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEK-ESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTG--SNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP------YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALD--ILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAP-LSSPLNGVHDRAYVAVDGIPQGVLERN-NVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSN-----ILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTS-APNTITVLELEWAPCSSDDPELCAVTFVDRPVIG--SSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6W2-1", "uniprot_id": "A0A8M2B6W2_DANRE", "id": "A0A8M2B6W2-1", "name": "Beta-galactosidase", "aln": "-------------MTPGVGLVSVLLLIIPAT--TYATTP-----TFSVDYHRNCFLKDGEPFRYISGSIHYSRIPRVYWKDRLLKMYMAGLNAIQTYVPWNFHEAVPGQYDFSGDRDLEQFLQLCQDIGLLVIMRPGPYICAEWDMGGLPAWLLKK-KDIVLRSSDPDYLAAVDKWMGKLLPIIKRYLYQNGGPIITVQVENEYGSYFACDFNYMRHLSQLFRFYLGEEAVLFTTDGAGLGYLKCGSLQGLYATVDFGPG--ANVTAAFEAQRHVEPRGPLVNSEFYPGWLDHWGEKHSVVPTSAVVKTLNEILEIGANVNLYMFIGGTNFGYWNGANTP------YGPQPTSYDYDSPLTEAGDLTEKYFAIREVIKMYKDVPEGILPPSTPKFAYGKVQMKKLKTVSETLD--VLSFSGPVKTLYPPTFIEMNQAFGFVLYQTVLPVNCVKPTP-LSSPLNGVHDRAYISIDGTAAGILERN-KALSINITGKAGSRVDVLVENMGRINYGKGINDFKGLVFNLTLGAD-----VLVNWTVYSLSVDEAVSKGLLLASGSSS---TSSTSTPPPALSPPTFYTGSFIIPDGIPDLPQDTYIQFPDWRKGQVWINGFNVGRYWPSRGPQITLFVPAHLLSTS-VQNNITVLELEASPCSSGS---CMVEFTDTPILN--GTVNGQYKRQLFNKQDLF--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B1WBS6-1", "uniprot_id": "B1WBS6_RAT", "id": "B1WBS6-1", "name": "beta-galactosidase", "aln": "-----------MPPD----LPSLLLRLVILLLLSQAEAR-----SFVVDRQHDRFLLDGVPFRYISGSLHYFRVPRVLWADRLLKMKLSGLNAVQFYVPWNYHEPEPGIYNFNGSRDLTAFLNEAAKANLLVILRPGPYICAEWEMGGLPSWLLRN-RDIHLRTSDPAFLHAVDSWFKVLLPKIYPFLYHNGGNIISIQVENEYGSYKVCDFKYMRHLAGLFRALLGDEILLFTTDGPQG--LRCGSLQGLYATVDFGPA--DNVTRIFSLLREYEPHGPLVNSEYYTGWLDYWGQNHSTRSTPAVARGLERILKLGASVNMYMFHGGTNFGYWNGADDKGY----FLPITTSYDYDAPISEAGDPTPKLFAIQNVISKFQEIPLGPLPPPSPKMKLGPLTMSLDGNLLSFLD--FLCPEGPIHSVLPLTFEAVKLDRGFMLYRTYMTYTVSEPTP-LWVPNNGIHDRAYVMVDGVLKGILERS-LKEELYLTGKVGTRLDILLENMGRLSFGSNHSDFKGLLEPPLLGQT-----VLTGWMMFPLKVDKLVKWWIP---------LQLMKRAQPQAPSVPAFYSAKFPALG----LLGDTFLYLPGWTKGQVWINGFNLGRYWTMRGPQQTLYVPRPLLFGS-SINKITLLELEDVPHDP------QIQFLDKPILN--STLHWG-YNYLLSEPQGSYEPIELSGH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC60-1", "uniprot_id": "GLB1L_MOUSE", "id": "Q8VC60-1", "name": "Beta-galactosidase-1-like protein", "aln": "-----------MPPD----LPSLLLRLVVLLLLSQAEAR-----SFVVDREHDRFLLDGVPFRYVSGSLHYFRVPPVLWADRLLKMQLSGLNAVQFYVPWNYHEPEPGIYNFNGSRDLIAFLNEAAKVNLLVILRPGPYICAEWEMGGLPSWLLRN-PNIHLRTSDPAFLEAVDSWFKVLLPKIYPFLYHNGGNIISIQVENEYGSYKACDFKYMRHLAGLFRALLGDKILLFTTDGPHG--LRCGSLQGLYTTIDFGPA--DNVTRIFSLLREYEPHGPLVNSEYYTGWLDYWGQNHSTRSSPAVAQGLEKMLKLGASVNMYMFHGGTNFGYWNGADEKGR----FLPITTSYDYDAPISEAGDPTPKLFAIRNVISKFQEIPLGPLPPPSPKMKFGPLTMSLDGNLLSFLD--FLCPQGPIHSVLPLTFEAVKLDHGFMLYRTYLTSPVLEPTP-FWVPNNGIHDRAYVMVDGVLKGVLERS-LKQELYLTGTVGTRLDILLENMGRLSFGSNHSDFKGLLEAPLLGQT-----ILTEWMMFPLKVDKLVKWWFP---------LQLMKRALPQASSVPAFYSAKFPVFG----LLGDTFLYLPGWTKGQVWINGFNLGRYWTMRGPQQTLYVPRLLLFGR-SINKITLLELENVPHNP------QVQFLDKPILN--STLHWG-YNFLLSETQGSFEPMELSGH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWU2-1", "uniprot_id": "GLB1L_HUMAN", "id": "Q6UWU2-1", "name": "Beta-galactosidase-1-like protein", "aln": "-----------MAPKKLSCLRSLLLPLSLTLLLPQADTR-----SFVVDRGHDRFLLDGAPFRYVSGSLHYFRVPRVLWADRLLKMRWSGLNAIQFYVPWNYHEPQPGVYNFNGSRDLIAFLNEAALANLLVILRPGPYICAEWEMGGLPSWLLRK-PEIHLRTSDPDFLAAVDSWFKVLLPKIYPWLYHNGGNIISIQVENEYGSYRACDFSYMRHLAGLFRALLGEKILLFTTDGPEG--LKCGSLRGLYTTVDFGPA--DNMTKIFTLLRKYEPHGPLVNSEYYTGWLDYWGQNHSTRSVSAVTKGLENMLKLGASVNMYMFHGGTNFGYWNGADKKGR----FLPITTSYDYDAPISEAGDPTPKLFALRDVISKFQEVPLGPLPPPSPKMMLGPVTLHLVGHLLAFLD--LLCPRGPIHSILPMTFEAVKQDHGFMLYRTYMTHTIFEPTP-FWVPNNGVHDRAYVMVDGVFQGVVERN-MRDKLFLTGKLGSKLDILVENMGRLSFGSNSSDFKGLLKPPILGQT-----ILTQWMMFPLKIDNLVKWWFP---------LQLPKWPYPQAPSGPTFYSKTFPILG----SVGDTFLYLPGWTKGQVWINGFNLGRYWTKQGPQQTLYVPRFLLFPRGALNKITLLELEDVPLQP------QVQFLDKPILNSTSTLHRTHINSLSADTLSASEPMELSGH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMJ5-1", "uniprot_id": "Q9VMJ5_DROME", "id": "Q9VMJ5-1", "name": "beta-galactosidase", "aln": "MSGCRRNRKLTMAVSGCLIIAVMALTVGLCVGLSGDTDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRSRLRTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRPGPYICAERDNGGLPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRLQHLFVGNGGKIIMVQVENEYGDY-ACDHDYLNWLRDETEKYVSGKALLFTVDIPNEK-MSCGKIENVFATTDFGIDRINEIDKIWAMLRALQPTGPLVNSEFYPGWLTHWQEQNQRRDGQEVANALRTILSYNASVNLYMFFGGTNFGFTAGANYNLDGGIGYAADITSYDYDAVMDEAGGVTTKYNLVKAVIGEFLPLPEITLNP-AKRLAYGRVELTPKLTLLSTEGRAALSKGDPVESIKPKTFEELDLYSGLVLYETELPSMDLDPAL---LKIDQINDRAHVFVDQELVGTLSREAQIYSLPLSKGWGSTLQLLVENQGRVNFYIS-NDTKGIFGEVSLQLHNGGYLPLENWRSTAFPLEQSAVELWR-REHTDEKALDPLLARQRILRNGPILYTGSLTVTE-----VGDTYLNMAGWGKGVAYVNGFNLGRYWPVAGPQVTLYVPNEILKVG--ENSLVILEYQRANKTATGEDLPAVQFDAVAQLD------GESGDVPLK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * :* : *: ** ****:***:** * * .** .* :**:*:: ** *. *:. * *::. *: *:. . .: :*:********* : **** **: : .* :*:.** :: *..* *:* : : *** :* :*******.* .**..*:. * . :. . :***.* . : ** :..:::* *** :: : * :* ***:***:*.*** :* : :. :. * :* .*.**:*** *****.: **: : . ******: : ***. * * :: :* : :* : * : :: * : : : . *. .*:.:: * ** :. * :**.* :. .* : :.***:: :* * :.*. : : *: :::*:** **:.: .* **:. : * * .: : . * :* .: **:: :..* ** .::****:****. *** **:** :* *.:.:** : : * . :. ", "identical_positions": 177, "similar_positions": 166, "identity": "24.86%" }, { "cls_id": "homologset.agr.FB:FBgn0001091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04797-1", "uniprot_id": "G3P_RAT", "id": "P04797-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAAFSC--DKVDIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQAAEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K8S2-1", "uniprot_id": "A0A0G2K8S2_RAT", "id": "A0A0G2K8S2-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGHLVTRAAFSC--DKVDIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLGKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQVAEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M4G6-1", "uniprot_id": "F1M4G6_RAT", "id": "F1M4G6-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "-----------------------------------------------MTAASS----------------CAVPA------------------LSHRQDGGG-------------------GVSGFCRIGCLVTRAAFSSASGKVEIVAINDPFIDLNYMIYMFQYDSTRGKFNGTVKAEDGKLVTNGKAITIFQERDPANIKWGDAGAEYVVESTGNFTTMEKAGAHLKGGAKRVIISALLANAPMSVMGVNHEKYDNSLKIVSNASWPRSSMTTLASWKG-----------SIHAVTTTQKSVDGPSESCGVMG-GAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFCVPTPNVSIVDLTCCLEKPAKCDDIKKVVKQASEGPLKGILGYTEDQVFSCNFNSSFHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRLGNLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K3I6-1", "uniprot_id": "A0A0G2K3I6_RAT", "id": "A0A0G2K3I6-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "MEDKIFTHACTGCGEEDRLEIDADTANTTQDRCHVSGHLHVHHPNSIAAAASSTPCTTSNLLAAVVLRTSTIPAGLPNAMMPCLQLPAKESTLFKHLEGKRQSHLLLQCQPCLIDKMVKLSVNGFGRIGNLVTRAAFCSASGKVDIVAINDPFINLNYMVYIFQYDSTHGKLNGTVKAENGKLVINGKPITIFQEQDPANIKWGDAGAEYVVESTGVFTTVEKAGTHLKGGGKRVFISAPSADAPMFVMGVNHKKYDNSLKIVSNTSCTTNCLAPLAKVIPDNFGIVEGLMTTVHAITAPQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPHVSIMDLTCCLEKPAKYDDIKKVVKQAPEGPLKDILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16858-1", "uniprot_id": "G3P_MOUSE", "id": "P16858-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAAICS--GKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "S4R1W1-1", "uniprot_id": "S4R1W1_MOUSE", "id": "S4R1W1-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAAICS--GKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLSPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLENPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5RLD8-1", "uniprot_id": "A0A1D5RLD8_MOUSE", "id": "A0A1D5RLD8-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAATCS--GKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSIVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04406-1", "uniprot_id": "G3P_HUMAN", "id": "P04406-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "-----------------------------------------------MG-------------------------------------------------------------------KVKVGVNGFGRIGRLVTRAAFNS--GKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMA--SKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZME3-1", "uniprot_id": "D3ZME3_RAT", "id": "D3ZME3-1", "name": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVNHEKYDNSLKIVSNASCTTNCLGPLGKVIHDNFGIMEGLMTTVHAITATQKTVDGPSGKLWSDGRGAAQNIIPASTGAAEAVGKVIPELNGKLTGMAFHVPTPNVSVVDLTCCLEKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSFTFDAGAGIALNDNFEKLISWYDNEYGYSNRVVTSWPTWPPRSKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XJ10-1", "uniprot_id": "G3P_DANRE", "id": "Q5XJ10-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGINGFGRIGRLVTRAAFLT--KKVEIVAINDPFIDLDYMVYMFQYDSTHGKYKGEVKAEGGKLVIDGHAITVYSERDPANIKWGDAGATYVVESTGVFTTIEKASAHIKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLTVVSNASCTTNCLAPLAKVINDNFVIVEGLMSTVHAITATQKTVDGPSGKLWRDGRGASQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTVRLEKPAKYDEIKKVVKAAADGPMKGILGYTEHQVVSTDFNGDCRSSIFDAGAGIALNDHFVKLVTWYDNEFGYSNRVCDLMAHMA--SKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07486-1", "uniprot_id": "G3P1_DROME", "id": "P07486-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 1", "aln": "--------------------------------------------------------------------------------------------------------------------MSKIGINGFGRIGRLVLRAAIDKG---ASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYSPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEEASKGPLKGILGYTDEEVVSTDFFSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQ--SKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00359-1", "uniprot_id": "G3P3_YEAST", "id": "P00359-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 3", "aln": "--------------------------------------------------------------------------------------------------------------------MVRVAINGFGRIGRLVMRIALSR--PNVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHDDKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVA---KA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00358-1", "uniprot_id": "G3P2_YEAST", "id": "P00358-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 2", "aln": "--------------------------------------------------------------------------------------------------------------------MVRVAINGFGRIGRLVMRIALQR--KNVEVVALNDPFISNDYSAYMFKYDSTHGRYAGEVSHDDKHIIVDGHKIATFQERDPANLPWASLNIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSNSSIFDAAAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVA---KA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00360-1", "uniprot_id": "G3P1_YEAST", "id": "P00360-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 1", "aln": "--------------------------------------------------------------------------------------------------------------------MIRIAINGFGRIGRLVLRLALQR--KDIEVVAVNDPFISNDYAAYMVKYDSTHGRYKGTVSHDDKHIIIDGVKIATYQERDPANLPWGSLKIDVAVDSTGVFKELDTAQKHIDAGAKKVVITAPSSSAPMFVVGVNHTKYTPDKKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLEKEATYDQIKKAVKAAAEGPMKGVLGYTEDAVVSSDFLGDTHASIFDASAGIQLSPKFVKLISWYDNEYGYSARVVDLIEYVA---KA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** * . .::**:* . ..: .*.. ::*: *:.**:***** . * * ****::****:*****:* *:******** *** .**::*** * : :. *:** *: ...* :*.:****:. *.* :* .. .: *** *** *. :* **::*****:*** *: * ", "identical_positions": 84, "similar_positions": 52, "identity": "18.54%" }, { "cls_id": "homologset.agr.FB:FBgn0001092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16858-1", "uniprot_id": "G3P_MOUSE", "id": "P16858-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--MVKVGVNGFGRIGRLVTRAAICSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "S4R1W1-1", "uniprot_id": "S4R1W1_MOUSE", "id": "S4R1W1-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--MVKVGVNGFGRIGRLVTRAAICSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLSPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLENPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5RLD8-1", "uniprot_id": "A0A1D5RLD8_MOUSE", "id": "A0A1D5RLD8-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--MVKVGVNGFGRIGRLVTRAATCSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSIVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04797-1", "uniprot_id": "G3P_RAT", "id": "P04797-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--MVKVGVNGFGRIGRLVTRAAFSCDKVDIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQAAEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04406-1", "uniprot_id": "G3P_HUMAN", "id": "P04406-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJ10-1", "uniprot_id": "G3P_DANRE", "id": "Q5XJ10-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--MVKVGINGFGRIGRLVTRAAFLTKKVEIVAINDPFIDLDYMVYMFQYDSTHGKYKGEVKAEGGKLVIDGHAITVYSERDPANIKWGDAGATYVVESTGVFTTIEKASAHIKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLTVVSNASCTTNCLAPLAKVINDNFVIVEGLMSTVHAITATQKTVDGPSGKLWRDGRGASQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTVRLEKPAKYDEIKKVVKAAADGPMKGILGYTEHQVVSTDFNGDCRSSIFDAGAGIALNDHFVKLVTWYDNEFGYSNRVCDLMAHMASKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07487-1", "uniprot_id": "G3P2_DROME", "id": "P07487-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 2", "aln": "--MSKIGINGFGRIGRLVLRAAIDKG-ANVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYIVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYKPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGASYDEIKAKVQEAANGPLKGILGYTDEEVVSTDFLSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00359-1", "uniprot_id": "G3P3_YEAST", "id": "P00359-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 3", "aln": "--MVRVAINGFGRIGRLVMRIALSRPNVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHDDKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00358-1", "uniprot_id": "G3P2_YEAST", "id": "P00358-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 2", "aln": "--MVRVAINGFGRIGRLVMRIALQRKNVEVVALNDPFISNDYSAYMFKYDSTHGRYAGEVSHDDKHIIVDGHKIATFQERDPANLPWASLNIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSNSSIFDAAAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00360-1", "uniprot_id": "G3P1_YEAST", "id": "P00360-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 1", "aln": "--MIRIAINGFGRIGRLVLRLALQRKDIEVVAVNDPFISNDYAAYMVKYDSTHGRYKGTVSHDDKHIIIDGVKIATYQERDPANLPWGSLKIDVAVDSTGVFKELDTAQKHIDAGAKKVVITAPSSSAPMFVVGVNHTKYTPDKKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLEKEATYDQIKKAVKAAAEGPMKGVLGYTEDAVVSSDFLGDTHASIFDASAGIQLSPKFVKLISWYDNEYGYSARVVDLIEYVAKA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:********** * * ::**:***** :* .*:.::*****:: * * :. ::::* *: :.****::: *.. ::*****. ::.* *:..***:*:*:***: ***** *** * . .::**********:******:* * * ****:***: *********** * **.** * ****:***********:* *:************ :**:**** :* : :.**:** *: *::* :**:****:. *** ** .: .:* *** *** *. :****::*****:*** ** **: :: . ", "identical_positions": 180, "similar_positions": 81, "identity": "53.73%" }, { "cls_id": "homologset.agr.FB:FBgn0001098", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26443-1", "uniprot_id": "DHE3_MOUSE", "id": "P26443-1", "name": "Glutamate dehydrogenase 1, mitochondrial", "aln": "MYRRLGEALLLSRAGPAALGSAAADSAALLGWARGQPSAAPQPGLTPVARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMS-------------VQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10860-1", "uniprot_id": "DHE3_RAT", "id": "P10860-1", "name": "Glutamate dehydrogenase 1, mitochondrial", "aln": "MYRRLGEVLLLSRAGPAALGSAAADSAALLGWARGQPSAVPQPGLTPVARRHYSEAATDREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRENEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGLGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMS-------------VQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00367-1", "uniprot_id": "DHE3_HUMAN", "id": "P00367-1", "name": "Glutamate dehydrogenase 1, mitochondrial", "aln": "MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEG-SILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMS-------------VQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49448-1", "uniprot_id": "DHE4_HUMAN", "id": "P49448-1", "name": "Glutamate dehydrogenase 2, mitochondrial", "aln": "MYRYLAKALLPSRAGPAALGSAANHSAALLGRGRGQPAAASQPGLALAARRHYSELVADREDDPNFFKMVEGFFDRGASIVEDKLVKDLRTQESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTMELAKKGFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEG-SILEVDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLS-------------VQESLERKFGKHGGTIPIVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEAGVTFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54385-1", "uniprot_id": "DHE3_DROME", "id": "P54385-1", "name": "Glutamate dehydrogenase, mitochondrial", "aln": "MYHLKSLARQGARRQQELATLAKALPTAVMQSSRGYATEHQIP-------DRLKDVPTAK--DPRFFDMVEYFFHRGCQIAEESLVDDMKGKLTRDEKKQKVKGILMLMQPCDHIIEIAFPLRRDAGNYEMITGYRAQHSTHKTPTKGGIRFSLDVSRDEVKALSALMTFKCACVDVPFGGAKAGLKINPKEYSEHELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGEREMSWIADTYAKTIGHLDINAHACVTGKPINQGGIHGRVSATGRGVFHGLENFINEANYMSQIGTTPGWGGKTFIVQGFGNVGLHTTRYLTRAGATCIGVIEHDGTLYNPEGIDPKLLEDYKNEHGTIVGYQNAKPYEGENLMFEKCDIFIPAAVEKVITSENANRIQAKIIAEAANGPTTPAADKILIDRNILVIPDLYINAGGVTVSFFEWLKNLNHVSYGRLTFKYERESNYHLLASVQQSIERIINDESVQESLERRFGRVGGRIPVTPSESFQKRISGASEKDIVHSGLDYTMERSARAIMKTAMKYNLGLDLRTAAYVNSIEKIFTTYRDAGLAF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39708-1", "uniprot_id": "DHE5_YEAST", "id": "P39708-1", "name": "NADP-specific glutamate dehydrogenase 2", "aln": "-----------------------------------------------------------MTSEPEFQQAYDEIVS---SVEDSKIFEKFP----------QYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRH--IGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEG----VLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNG-----KESFEGKRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAK---IRFKSLEEIVDEYSTFSESKMKYVAGAR---PWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVS---------------GLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLP----------SLVKGANIASFVMVADAMLDQGDVF-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P07262-1", "uniprot_id": "DHE4_YEAST", "id": "P07262-1", "name": "NADP-specific glutamate dehydrogenase 1", "aln": "------------------------------------------------------------MSEPEFQQAYEEVVS---SLEDSTLFEQHP----------EYRKVLPIVSVPERIIQFRVTWENDKGEQEVAQGYRVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTGLDMGGGKGGLCVDLKGRSNNEIRRICYAFMRELSRH--IGQDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEG----VLTGKGLNWGGSLIRPEATGYGLVYYTQAMIDYATNG-----KESFEGKRVTISGSGNVAQYAALKVIELGGTVVSLSDSKGCIISETGITSEQVADISSAK---VNFKSLEQIVNEYSTFSENKVQYIAGAR---PWTHVQKVDIALPCATQNEVSGEEAKALVAQGVKFIAEGSNMGSTPEAIAVFETARSTATGPSEAVWYGPPKAANLGGVAVS---------------GLEMAQNSQRITWTSERVDQELKRIMINCFNECIDYAKKYT--KDGKVLP----------SLVKGANIASFIKVSDAMFDQGDVF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.* . : .. .: :..:... . : :* ::. ::::.: .. ..* *. *: ***.*.. : * ***:*: .*. . :* *. :* : ..: :**.*.*: :: * :::*:.:* * **::: ** . **** *:..* **:.:: .:* . . : :*** :. ** * .*** *:.: : :*: *. . . .* . :.* ***. :: : . *. :.: : .* : . ** .: : * : : : . : . . .: *. . . :. .:. : . * : *. :. . :: . :.: ::: ** :. . : : : :* : .** . . . . * . :: :. . *: :. . : .* ..* : :: : . : * .* ", "identical_positions": 76, "similar_positions": 177, "identity": "13.29%" }, { "cls_id": "homologset.agr.FB:FBgn0001099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14129-1", "uniprot_id": "DGCR6_HUMAN", "id": "Q14129-1", "name": "Protein DGCR6", "aln": "-------MERYAGALEEVADGAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQALRQKHQEAQQACRPHNLPVLQAAQQRELE---AVEHRIREEQRAMDQKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELMLQMNLLELIRKLQQRGCWAGKAALGLGGPWQLPAAQCDQKGSPVPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BY27-1", "uniprot_id": "DGC6L_HUMAN", "id": "Q9BY27-1", "name": "Protein DGCR6L", "aln": "-------MERYAAALEEVADGAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQALRQKHQEAQQACRPHNLPVVQAAQQRELE---AVEHRIREEQRAMDQKIILELDRKVADQQSTLEKAGVAGFYVTTNPQELMLQMNLLELIRKLQQRGCRAGNAALGLGGPWQSPAAQCDQKGSPVPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7FP83-1", "uniprot_id": "F7FP83_RAT", "id": "F7FP83-1", "name": "", "aln": "-------MDRYAGAGDEAADRAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELEPWQALEHRIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRGCQMGKPAL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35347-1", "uniprot_id": "DGCR6_MOUSE", "id": "O35347-1", "name": "Protein DGCR6", "aln": "-------MDRYAAAGDEAADRAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELE---AMEHRIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRSCQVGKAAL----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22468-1", "uniprot_id": "GDL_DROME", "id": "P22468-1", "name": "Gonadal protein gdl", "aln": "MADIPATSEGSANTSEAVVEYQQPTPEFLQRKIYFLVDQLRTYHSELPENLQTRISYDLLTELANCVLNDGIFVIVKALMELQHETERHLIKIRMQAENEYEIEVAEWRSKIKDPEELR--HILGLMKIKHTKKLH--------------ESDTKIIEILDQKVNDQQSTLQKAGVPGFYVTENPKEIKIQMFLLDFILRLSRLKYEPGK-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : ..: : *.: * *:. *:: .***..:* *:** *::** .:*:. :* **:.*:*:** **: * : *:: :**:.: *.* :.:: * * ::: : ::*. * **: **:** ******:****.***** **:*: :** **::* :*.: *: ", "identical_positions": 66, "similar_positions": 62, "identity": "28.09%" }, { "cls_id": "homologset.agr.FB:FBgn0001104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04897-1", "uniprot_id": "GNAI2_RAT", "id": "P04897-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "aln": "MGCTVS-----AEDKAAAERSKM---IDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPQ--------------------------------------------------------------------------------------------------------RADDARQLFALSCAAEEQ-----GMLPEDLSGVIRRLWA-DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQSPLTICFPEYTGANKYDEAAS-YIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08752-1", "uniprot_id": "GNAI2_MOUSE", "id": "P08752-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "aln": "MGCTVS-----AEDKAAAERSKM---IDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPQ--------------------------------------------------------------------------------------------------------RADDARQLFALSCAAEEQ-----GMLPEDLSGVIRRLWA-DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQSSLTICFPEYTGANKYDEAAS-YIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04899-1", "uniprot_id": "GNAI2_HUMAN", "id": "P04899-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "aln": "MGCTVS-----AEDKAAAERSKM---IDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPS--------------------------------------------------------------------------------------------------------RADDARQLFALSCTAEEQ-----GVLPDDLSGVIRRLWA-DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAAS-YIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RSH2-1", "uniprot_id": "GNAI1_MOUSE", "id": "B2RSH2-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "aln": "MGCTLS-----AEDKAAVERSKM---IDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSA--------------------------------------------------------------------------------------------------------RADDARQLFVLAGAAEE------GFMTAELAGVIKRLWK-DSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAA-YIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63096-1", "uniprot_id": "GNAI1_HUMAN", "id": "P63096-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "aln": "MGCTLS-----AEDKAAVERSKM---IDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSA--------------------------------------------------------------------------------------------------------RADDARQLFVLAGAAEE------GFMTAELAGVIKRLWK-DSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAA-YIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10824-1", "uniprot_id": "GNAI1_RAT", "id": "P10824-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "aln": "MGCTLS-----AEDKAAVERSKM---IDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDAA--------------------------------------------------------------------------------------------------------RADDARQLFVLAGAAEE------GFMTAELAGVIKRLWK-DSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAA-YIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DC51-1", "uniprot_id": "GNAI3_MOUSE", "id": "Q9DC51-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "aln": "MGCTLS-----AEDKAAVERSKM---IDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGESA--------------------------------------------------------------------------------------------------------RADDARQLFVLAGSAEE------GVMTSELAGVIKRLWR-DGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAA-YIQCQFEDLNRRKDTKEVYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08753-1", "uniprot_id": "GNAI3_RAT", "id": "P08753-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "aln": "MGCTLS-----AEDKAAVERSKM---IDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAA--------------------------------------------------------------------------------------------------------RADDARQLFVLAGSAEE------GVMTSELAGVIKRLWR-DGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAA-YIQCQFEDLNRRKDTKEVYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08754-1", "uniprot_id": "GNAI3_HUMAN", "id": "P08754-1", "name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "aln": "MGCTLS-----AEDKAAVERSKM---IDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAA--------------------------------------------------------------------------------------------------------RADDARQLFVLAGSAEE------GVMTPELAGVIKRLWR-DGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAA-YIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20353-1", "uniprot_id": "GNAI_DROME", "id": "P20353-1", "name": "G protein alpha i subunit", "aln": "MGCAVST----ARDKEAIERSKN---IDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPS--------------------------------------------------------------------------------------------------------RTDIARQFFTHASAADE------GILLPEIVLLMKKLWA-DGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAAN-YIRMKFENLNKRKDQKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50149-1", "uniprot_id": "GNAT2_MOUSE", "id": "P50149-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-2", "aln": "MGSGIS-----AEDKELARRSKE---LEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYAEPS--------------------------------------------------------------------------------------------------------CADAGRQLNNLADSTEE------GTMPPELVDVIRKLWK-DGGVQACFDRAAEFQLNDSASYYLNQLDRITDPNYLPNEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAGN-YIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AA42-1", "uniprot_id": "D4AA42_RAT", "id": "D4AA42-1", "name": "", "aln": "MGSGIS-----AEDKELAKRSRE---LEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYAEPS--------------------------------------------------------------------------------------------------------CAEAGRQLNNLADSTEE------GTMPSELVEVIRKLWK-DGGVQACFDRAAEFQLNDSASYYLNQLDRITDPDYLPNEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAGN-YIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19087-1", "uniprot_id": "GNAT2_HUMAN", "id": "P19087-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-2", "aln": "MGSGAS-----AEDKELAKRSKE---LEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPS--------------------------------------------------------------------------------------------------------CADDGRQLNNLADSIEE------GTMPPELVEVIRRLWK-DGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYDDAGN-YIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20612-1", "uniprot_id": "GNAT1_MOUSE", "id": "P20612-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-1", "aln": "MGAGAS-----AEEK----HSRE---LEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSA--------------------------------------------------------------------------------------------------------RQDDARKLMHMADTIEE------GTMPKEMSDIIQRLWK-DSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYEDAGN-YIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSS5-1", "uniprot_id": "D3ZSS5_RAT", "id": "D3ZSS5-1", "name": "", "aln": "MGAGAS-----AEEK----HSRE---LEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSA--------------------------------------------------------------------------------------------------------RQDDARKLMHMADTIEE------GTMPKEMSDIIQRLWK-DSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYDDAGN-YIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11488-1", "uniprot_id": "GNAT1_HUMAN", "id": "P11488-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-1", "aln": "MGAGAS-----AEEK----HSRE---LEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSA--------------------------------------------------------------------------------------------------------RQDDARKLMHMADTIEE------GTMPKEMSDIIQRLWK-DSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDGPNTYEDAGN-YIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3V3I2-1", "uniprot_id": "GNAT3_MOUSE", "id": "Q3V3I2-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "aln": "MGSGIS-----SESKESARRSKE---LEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVIYSNTLQSILAIVKAMATLGIDYVNPR--------------------------------------------------------------------------------------------------------SREDQEQLHSMANTLED------GDMTPQLAEIIKRLWG-DPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVAKVHLSICFPEYTGPNTFEDAGN-YIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29348-1", "uniprot_id": "GNAT3_RAT", "id": "P29348-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "aln": "MGSGIS-----SESKESAKRSKE---LEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVVYSNTLQSILAIVKAMTTLGIDYVNPR--------------------------------------------------------------------------------------------------------SREDQQLLLSMANTLED------GDMTPQLAEIIKRLWG-DPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDLFQEKVTKVHLSICFPEYTGPNTFEDAGN-YIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MTJ3-1", "uniprot_id": "GNAT3_HUMAN", "id": "A8MTJ3-1", "name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "aln": "MGSGIS-----SESKESAKRSKE---LEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPR--------------------------------------------------------------------------------------------------------SAEDQRQLYAMANTLED------GGMTPQLAEVIKRLWR-DPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDAGN-YIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19086-1", "uniprot_id": "GNAZ_HUMAN", "id": "P19086-1", "name": "Guanine nucleotide-binding protein G(z) subunit alpha", "aln": "MGCRQS-----SEEKEAARRSRR---IDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPD--------------------------------------------------------------------------------------------------------RAYDAVQLFALTGPAESK-----GEITPELLGVMRRLWA-DPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAV-YIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08539-1", "uniprot_id": "GPA1_YEAST", "id": "P08539-1", "name": "Guanine nucleotide-binding protein alpha-1 subunit", "aln": "MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLSLN--KTNKPIYVKRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. * ... ..: ::: *: : :: :******:.:*****::**:*::*. *:. : :: :: :.::*: :: * *: : . : . : :: :::** * * : .* *: *::*:..*.**:..:::: . *: . :*:*: * **** *..*. . *::.*.****************:*.::* :* ** * **:. .** **: **::: * .:* *.::***** *:: **: : :*:* * :*. *:. * .** : * :* : ******..::**:.****:**::*** *: ", "identical_positions": 115, "similar_positions": 120, "identity": "24.26%" }, { "cls_id": "homologset.agr.FB:FBgn0001105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52287-1", "uniprot_id": "GBB3_RAT", "id": "P52287-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "aln": "-----------------------------------MGEMEQLKQEAEQLKKQIADARKACADITLAELVSGLEVVGR--VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSREGNVK-VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPD------YKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYS---------------HESIIC--------------------GITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVG----VLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61011-1", "uniprot_id": "GBB3_MOUSE", "id": "Q61011-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "aln": "-----------------------------------MGEMEQLRQEAEQLKKQIADARKACADITLAELVSGLEVVGR--VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVK-VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPD------YKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYS---------------QESIIC--------------------GITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVG----ILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16520-1", "uniprot_id": "GBB3_HUMAN", "id": "P16520-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "aln": "-----------------------------------MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGR--VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVK-VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPD------FNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS---------------HESIIC--------------------GITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVG----ILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62873-1", "uniprot_id": "GBB1_HUMAN", "id": "P62873-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "-----------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPD------TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS---------------HDNIIC--------------------GITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54311-1", "uniprot_id": "GBB1_RAT", "id": "P54311-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "-----------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPD------TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS---------------HDNIIC--------------------GITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62874-1", "uniprot_id": "GBB1_MOUSE", "id": "P62874-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "-----------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPD------TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS---------------HDNIIC--------------------GITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PH57-1", "uniprot_id": "GBB1_DANRE", "id": "Q6PH57-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "aln": "-----------------------------------MSELDQLRQEAEQLKNQIRDARKACADATLSQITANIDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAPD------TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYS---------------HDNIIC--------------------GITSVAFSKSGRLLLAGYDDFNCNVWDALKADRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62880-1", "uniprot_id": "GBB2_MOUSE", "id": "P62880-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVR-VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPD------GRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS---------------HDNIIC--------------------GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62879-1", "uniprot_id": "GBB2_HUMAN", "id": "P62879-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVR-VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPD------GRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS---------------HDNIIC--------------------GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54313-1", "uniprot_id": "GBB2_RAT", "id": "P54313-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVR-VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPD------GRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS---------------HDNIIC--------------------GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BCL1-1", "uniprot_id": "A0A8M2BCL1_DANRE", "id": "A0A8M2BCL1-1", "name": "", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGR--IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKIHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVR-VSRELPGHTGYLSCCRFIDDNQIITSSGDTTCALWDIETGQQTTLFSGHSGDVMSLSLAPD------SRTFISGACDASIKLWDIRDSMCRQTFTGHESDINAACFFPSGSAFATGSDDATCRLFDLRADQELCLYS---------------HDNIIC--------------------GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGERAGKHTGVLAGHDNRVSCLGVTDDGMAVCTGSWDSFLKIWN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29387-1", "uniprot_id": "GBB4_MOUSE", "id": "P29387-1", "name": "Guanine nucleotide-binding protein subunit beta-4", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGR--IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPD------LKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYS---------------HDNIIC--------------------GITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35353-1", "uniprot_id": "GBB4_RAT", "id": "O35353-1", "name": "Guanine nucleotide-binding protein subunit beta-4", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGR--IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPD------LKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYS---------------HDNIIC--------------------GITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HAV0-1", "uniprot_id": "GBB4_HUMAN", "id": "Q9HAV0-1", "name": "Guanine nucleotide-binding protein subunit beta-4", "aln": "-----------------------------------MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGR--IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR-VSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPD------MRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYS---------------HDNIIC--------------------GITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAG----VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26308-1", "uniprot_id": "GBB1_DROME", "id": "P26308-1", "name": "Guanine nucleotide-binding protein subunit beta-1", "aln": "-----------------------------------MNELDSLRQEAESLKNAIRDARKAACDTSLLQAATSLEPIGR--IQMRTRRTLRGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPSGSYVACGGLDNMCSIYNLKTREGNVR-VSRELPGHGGYLSCCRFLDDNQIVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSLAPQ------CKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFDIRADQELAMYS---------------HDNIIC--------------------GITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERSG----ILAGHDNRVSCLGVTENGMAVATGSWDSFLRVWN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6DH55-1", "uniprot_id": "Q6DH55_DANRE", "id": "Q6DH55-1", "name": "", "aln": "-----------------------------------MGEMEQLRKEAEKLKDDITAARKTVQDLTLQDHVAGTAVVGR--VQLKTRKTLRGHLAKIYAMHWGTDSKLCVSASQDGKLIVWDSYTTNKVHAIPLKSSWVMTCSYAPSGNMVACGGLDNMCSIYNLKAKDGNVK-VMRELAAHTGYLSCCRFLSDSEIITSSGDCTCVLWDIETGSQKTVFAGHLGDCMSLAVSPD------FNTFISGACDFTAKLWDIREGQCRQTFGGHESDINAIGFFPNGNAVITGSDDASCKLYDLRSDQELITYQ---------------DSSIMC--------------------GVTSIAPSLSGRLILAGYDDFNCNIWDSLKSERVG----VLSGHDNRVSCIGVTPDGMACCTGSWDSFLKIWN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18851-1", "uniprot_id": "GBB_YEAST", "id": "P18851-1", "name": "Guanine nucleotide-binding protein subunit beta", "aln": "MAAHQMDSITYSNNVTQQYIQPQSLQDISAVEDEIQNKIEAARQESKQLHAQINKAKHKIQDASLFQMANKVTSLTKNKINLKPNIVLKGHNNKISDFRWSRDSKRILSASQDGFMLIWDSASGLKQNAIPLDSQWVLSCAISPSSTLVASAGLNNNCTIYRVSKENRVAQNVASIFKGHTCYISDIEFTDNAHILTASGDMTCALWDIPKAKRVREYSDHLGDVLALAIPEEPNSENSSNTFASCGSDGYTYIWDSRSPSAVQSFYVNDSDINALRFFKDGMSIVAGSDNGAINMYDLRSDCSIATFSLFRGYEERTPTPTYMAANMEYNTAQSPQTLKSTSSSYLDNQGVVSLDFSASGRLMYSCYTDIGCVVWDVLKGEIVG----KLEGHGGRVTGVRSSPDGLAVCTGSWDSTMKIWSPGYQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: ::*::.*: * *:: * :* : . : : ::::.. .*:** ** ::*. **: :****** :::**: : * :**** *.**::*: :**.. **..**:* *:** :. .: .: * : .* *:* .* .: .*:*:*** :* **** .. : : .* ** ::*::. : . * * ..* :** *. . *:* : ***** ** .* :. :***:.: .::*:*:* .: :. .: *:.*: * ****: : * *:.* :** :* * * **..**: : : :*:* .****** :::*. ", "identical_positions": 110, "similar_positions": 121, "identity": "25.76%" }, { "cls_id": "homologset.agr.FB:FBgn0001108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28023-1", "uniprot_id": "DCTN1_RAT", "id": "P28023-1", "name": "Dynactin subunit 1", "aln": "MAQSKRHMYNRTPSG--SRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDG---------ADTTSPETPDSSASKILKREGADAAAKTSKLRGLK-PKKAPTARKTTTRRPKPTRPASTGVAGPSSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPT------------------PALTSPG-----AAPPLPSPSKEEEGLRDQVRDLEEKLETLRLKRSEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA-KEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-----------DGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPP-----PETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEESTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLD--CRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPSSSPYECLRQSCSILISTMNKLATAMQEGEYDAERPPSKPP----------PVEPWPAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQTLLRKKEKEFEETMDALQADIDQLEAEKTELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGGTPGQAPGALPGPGPVKDSPLLLQQISAMRLHISQLQHENSILRGAQMKASLAALPPLHVAKFSLPPHEGPGGNLLSGALYRKTSQLLEKLNQLSTYTHVVDITRSSPACKSPSAQLMEQVAQLKSLSDTIEKLKDEVLKETVTQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHGRLIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08788-1", "uniprot_id": "DCTN1_MOUSE", "id": "O08788-1", "name": "Dynactin subunit 1", "aln": "MAQSRRHMSSRTPSG--SRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDG---------ADTTSPETPDSSASKVLKREGADAAAKTSKLRGLK-PKKAPTARKTTTRRPKPTRPASTGVAGPSSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPT------------------PALTSPG-----AAPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRSEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-----------DGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPP-----PETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQGGQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLD--CRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPSSSPYECLRQSCTILISTMNKLATAMQEGEYDAERPPSKPP----------PVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDETQTLLRKKEKDFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEPQRGGAPGQAPGALPGPGLVKDSPLLLQQISAMRLHISQLQHENSILRGAQMKASLAALPPLHVAKLSLPPHEGPGGNLVAGALYRKTSQLLEKLNQLSTHTHVVDITRSSPAAKSPSAQLMEQVAQLKSLSDTIEKLKDEVLKETVTQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHSRLIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14203-1", "uniprot_id": "DCTN1_HUMAN", "id": "Q14203-1", "name": "Dynactin subunit 1", "aln": "MAQSKRHVYSRTPSG--SRMSAEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDG---------ADTTSPETPDSSASKVLKREGTDTTAKTSKLRGLK-PKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPT------------------PVLTSPG-----AVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-----------DGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPP-----PETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGPQVSDTLLD--CRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLLVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPP----------PVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVAKLS---HEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGFGQRHRLVLTQEQLHQLHSRLIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFT7-1", "uniprot_id": "A0A8M9QFT7_DANRE", "id": "A0A8M9QFT7-1", "name": "Dynactin subunit 1", "aln": "MSQMKRYTYSRTTSSGSSRMSSDGGGRPVKVGSLVEVIGKGHRGTVAYIGNTLFASGKWVGVILDEPKGKNDGTVQGKRYFLCQENHGIFVRQSQIQLVEDG---------ADTTSPETPEALTSKMLKREIIEG-LKSNKVRGTK-PKKAPTTRKTTTRRPKQTR------AGVGVKVG-SGSASAGEMSSSEPSTPAQTPLAAPVIPS------------------PVGALPSP----GAPPIPGPSKEEESLRALVKDLEEKLETLKMKRTEDKAKLKELEKHKIQLEQLQEWKSKMQEQQNELQKQLKEAKREAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQLEADALKERVDELTMDLEILKHEIEEKGS-----------DGAASSYHVKQLEEQNARLKEALVRMRDLSASEKQEHGKQQKLMEKKNFELDALRCHKEKLQEEMKMAEKTIDELKEQVDASLGAEEMVEMLTERNLDLEEKVRELRETVADLEAINEMNDELQENARETELELREQLDLGAAGVREAEKRVEAAQETVADYQQTIQKYRELTANLQEVNRELMSQQEANSEQQQQP------AEIFDFKIKFAETKAYAKAIEMELRKMEVIQANRQVSLLISFMPDSFLKHRGDHDCILALLLIPRLICKSELISKQAQEKFELTESCSQKPGMRGAVGERLSFAAGLIYSLTLLQAALHKYEHALSQCSVDVYKRVGSLYSELSVHERSLDFLIDLLYKDLLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEDCTMQLADHIRFTQSALDCMAVEVGRLRAFIQTGQDEEAFCVLLKDLDTSCSDIRQFCKKIRRRMPGTDAPGIPAALSFGPQVCEALAD--SRRQLAWVNAVLQEVAAAAAQLIAPLSEHEGLPAVKLEDMAFKAAEQIYGSQGINAQECLRQSCSVVIATMNKMATAMQEGEYDSDRPQTGIS----------PVEVRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSASKDADERVEKIQAILDETDSLLKKKEKEFEETMDALQADIDQLESEKVELKHRISSQSKMTIESLRGSQASGIASIVTCGITAEEQKGVCAAAG-------LQVIDSPLLTQQIEAQRLSIKHLKNENNRLKAERMRAQLASLPPLNVPKLG--WREGCRPEVLSSALYRKTDQLLDTLLQMSANVKVVDITGRSPVS--PSAQLLEQTARLQSLNDTLDRLKDEVAEHVVTHRPGAQVSSDFATFPCTSFVKAKEEKRGDAVLVGRVMMPCARGQEQVHRLVLSQTQIHRVHRLLQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58FY45-1", "uniprot_id": "A0AC58FY45_DANRE", "id": "A0AC58FY45-1", "name": "Dynactin subunit 1", "aln": "-------------------MSSDGGGRPVKVGSVVEVIGKGQRGTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGG--------SSATSPETPDSGVAKLLKKEIQETPKTAKQTPAVKKPPVRRSTKWSTPGRLSTSSSLPSLIMTGRPSVG-GSALSESVLAESESSSSTQMSLAAPVVPQ------------------PSTASTP------APATP--SKEEESLRAQLKDLEEKLETLRMKRSEDKAKLKEMEKYKIQLEQLQEWRSKMQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGS-----------DGAASSYHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLRSQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPA-----AELFDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLC-DQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALAD--SRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQGLNPYECLRQSCSAVIATMNKMATAMQEGEYDSERPQRPPP----------PVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTSTKDADERVEKIQTKLDEALNTLKKKEKEFEETMDALQADIDQLESEKAELKQRISSQS-RATEGLRGQPASGIASIVTGNVAGGMLSAPAGVSG------VVQVVDSPLLKQQIDVQRIAIKQLKSENYRLKAERMRAQLSSLPPLQVPNMK---SVMMKENTAAGALQRKTDVLLHNLMKMSAGLKVVDITGKTTAS--ASAQLLEQTAKMKSLSDALDKLQAEVSQHVVSQQPGASVPSDFATFPTATFVKAQQEQQSGCVLVSKLMIPCARGKEQKHTLVLSQQQLQRVHHLLMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13496-1", "uniprot_id": "DCTN1_DROME", "id": "P13496-1", "name": "Dynactin subunit 1", "aln": "-----------------------MSEKNLKVGARVELTGKDLLGTVAYVGMTSFAVGKWVGVVLDEPKGKNSGSIKGQQYFQCDENCGMFVRPTQLRLLEAAPGSRRSIEDVSGATPTAAQPTKARLSSSRTSLSSSRQSLLGSRTQLTTSLSERTASSSSIGPRKSLAPQNSKDKESPSTSLAEGAPAASGGNGAASHASSKRASFVETGFLEILKPQFTPSQPLRSPSFTMPSNSGAEDKVALLEAQKTSAELQAQLADLTEKLETLKQRRNEDKERLREFDKMKIQFEQLQEFRTKIMGAQASLQKELLRAKQEAKDAIEAKEQHAQEMADLADNVEMITLDKEMAEEKADTLQLELESSKERIEELEVDLELLRSEMQNKAESAIGNISGGGDSPGLSTYEFKQLEQQNIRLKETLVRLRDLSAHDKHDIQKLSKELEMKRSEVTELERTKEKLSAKIDELEAIVADLQEQVDAALGAEEMVEQLAEKKMELEDKVKLLEEEIAQLEALEEVHEQLVESNHELELDLREELDLANGAKKEVLRERDAAIETIYDRDQTIVKFRELVQKLNDQLTELRDRNSSNEKESLQDPSLKMVTETIDYKQMFAESKAYTRAIDVQLRQIELSQANEHVQMLTAFMPESFMSRGGDHDSILVILLISRIVFKCDIVVSQTRERFPPVDAITREAVTQGHAVQQYAFKCRLLHYVHSLQCALHQILYGLNSCQPDTLLRAGSSLPEMVAQEKIVDGIIELLKSNQLDENSTTDNIEKCVAFFNAMNSVLLAGEQLLNEIQMIRDCVASLGAACESILSDTAIAKVIIQEAGATSDSVLLIQFLNENMESVRQQVKLIKRRLPSDQHVIKSGLSQHKVEAMRGLAQNISRIMSAMHQATKQSLAAIVSTIESDNAAEHTLPQEKYWALLTASCERIYEQDDRGPTQNFKTLLAQANSDLQLIAQHLLDKEYDIISAANNASNQQKSGAHSTPITQRAQLIKKQLEQKNVLAATLENREADVKQLKVAAKMKQNELSEMQIRKDLAEKKLSVLQNEYEHAVDKWKQKYEETSLQLQLKEKEFEETMDHLQSDIDALESEKSDLRDKLKLNSTTGKVQPGSESHSPHNISLSGNTSTAPGISNVSYSAP--------AGTAPVVAEEVELLKNAFNQERNQRLRLQAQDMRAKLSQFEPLHVPQPQ-----DQRITALESELTRMKHAWVLSLLQVRSQDSVNSGTRIDAVALQRRNQPVPLKG---EISSKASQLASDILTEYLQRKPHRATHGQFASFPTVDVKRVLQI-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::**: **: **. *****:* * ** ******:***.****.*:::*::** *:*. *:*** :*:::.: . . ::* :.:. ::: . . . . . : : ::. . . . : . : .: ::. . *..: * : . . .* . *: : ** ******: :* *** :*:*::* ***:**:**:::*: * .**:.* .* :**::*:***::: :**** ** :** *********:*::** * :: **:::** *:*:*: *:::*.. . . *:*..****:** ***::***:****: :*:: * .* :* *. *: :. :*:*. ::. * : :*:*****:******** *::::::**:**: *.* :.:**:::*::::* *. :* **:***:**:. . :*. :. :** **: * :*** *:*:*. :*:: ** .::.:. :. * .* :*:* ***:**:::**:::**::*: ***.::.:* :***:**: ****.:*.:**:.*:: *.::: .*::*:* ... :* . :: :* . *:: : **.:**: .*. * *. : * .*: .:*: :* :*:** .: ***. .: : *.: ::: : *: *. :* : : * : :* :.: :.. :.::* . :*:: *: . . ** * *:**:*. : .. . :. * : .* : *. *.::* : : : .. * : : *::* . .. : :: : :: :* : : *** . . *: . :: :: : : *. .**:**: :*:** : *:* :**** ::* .* ****. :: :. ::* : :*: *: ***:****** **:*** **:** :*:.::. :* . * :: . . . :*:: :::. : :.: : :. *:. *:*.*: : **:*.: . * * . : .* :: : * . * ... * : . .:.. .:* :: . : ::* . :**:** . :. : ", "identical_positions": 332, "similar_positions": 426, "identity": "24.68%" }, { "cls_id": "homologset.agr.FB:FBgn0001112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UPE0-1", "uniprot_id": "CHDH_RAT", "id": "Q6UPE0-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "MWQVLRSWSKRCLSPRGALAWAAQG-------------------QPRPPCSCAVASAASGGKDEYTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCDDKYNWYYHTEAQPGLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAHCLPYFRKAQK---HELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTIHQGKRWSTASAYLRPALSRPNLRAEVQTLVSRVLFEG--TRAVGVEYIKD-GQSHKAYVSREVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQHACTQPITLHSAQKPLRKVCIGLEWLWRFTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRK----PTQQEAYQVHVGTMRATSVGWLKLRSTNPQDHPMINPNYLSTETDVEDFRQCVKLTREIFAQEAFAPFRGKELQ------PGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDQQTRVIGVENLRVIDASIMPSVVSGNLNAPTIMIAEKAADVIKGCPALGDENVPVYKPQTLDTQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ64-1", "uniprot_id": "CHDH_MOUSE", "id": "Q8BJ64-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "MWQVLRGWRKGWQSPRGALAWAVQG-------------------QPCPPCSRAVASVG---KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQR---HELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFEG--TRAVGVEYIKD-GQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRK----PTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQ------PGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NE62-1", "uniprot_id": "CHDH_HUMAN", "id": "Q8NE62-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "MWCLLRGLGR-----PGALARGALG-------------------QQQSLGARALASAGSESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQG---HELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSRTNLKAEAETLVSRVLFEG--TRAVGVEYVKN-GQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRV----PTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKELQ------PGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18173-1", "uniprot_id": "DHGL_DROME", "id": "P18173-1", "name": "Glucose dehydrogenase [FAD, quinone]", "aln": "MSASASACDCLVGVPTGPTLASTCGGSAFMLFMGLLEVFIRSQCDLEDPCGRASSRFRSEPDYEYDFIVIGGGSAGSVVASRLSEVPQWKVLLIEAGGDEPVG-----AQIPSMFLNFIGSDIDYRYNTEPEPMACLSSMEQRCYWPRGKVLGGTSVLNGMMYVRGNREDYDDWAADGNPGWAYNDVLPFFKKSEDNLDLDEVGTEYHAKGGLLPVGKFPYNPPLSYAILKAGEELGFS-VHDLNGQNSTGFMIAQMTARNGIRYSSARAFLRPARMRNNLHILLNTTATKILIHPHTKNVLGVEVSDQFGSTRKILVKKEVVLSAGAVNSPHILLLSGVGPKDELQQVNVRTVHNLPGVGKNLHNHVTYFTNFFIDDADTAPLNWATAMEYLLFRDGLMSGTGISDVTAKLATRYADS-PERPDLQLYFGGYLASCARTGQVGELLSNNSRSIQIFPAVLNPRSRGFIGLRSADPLEPPRIVANYLTHEQDVKTLVEGIKFVIRLSQTTPLKQYGMRLDKTVVKGCEAHAFGSDAYWECAVRQNTGPENHQAGSCKMGPSHDPMAVVNHELRVHGIRGLRVMDTSIMPKVSSGNTHAPAVMIAEKGAYLLKR---AWGAKV------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *. .. * : . * : ** ::*:*.****.*:*.**:* * :***:*** .: : * ::.. * :** .. . : *****:* **:* **.*:*:**: ***: * :* ** * . **:*:*:: : .. *:. .* * *.: * ** *:*:* .: *:. ..*:** :. ** :** ::* *:*:* *:*:*. * **: :* .:::*:. ...:*** .: *. :: ..:**:**.**:***::*:***:* *:*:::.: .* :*****:**::*: : : . * . : : : * ** . .: : : * * *. :: * :. *: ..:..: *:. . :. * *:: ***::* : * * .***: * *:: : ::: .: .: : : : . . ** :. ** ::.. * : :**** . ** ***: : :* *:..***:*:****.: *** :**::*****.* ::* . .* ", "identical_positions": 174, "similar_positions": 186, "identity": "27.44%" }, { "cls_id": "homologset.agr.FB:FBgn0001122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59215-1", "uniprot_id": "GNAO_RAT", "id": "P59215-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "--------------------------------------------------------------------------MGCTLS----AEERAA-------LERSK----AIEKNLKEDGI-SAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKE---------------------------------------------------------------------RKADSKMVCDVVSRMEDTEP----------------------------------------FSAELLSAMMRLWG-DSGIQECFN-RSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFK-NLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSN-TYEDAAAYIQTQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18872-1", "uniprot_id": "GNAO_MOUSE", "id": "P18872-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "--------------------------------------------------------------------------MGCTLS----AEERAA-------LERSK----AIEKNLKEDGI-SAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKE---------------------------------------------------------------------RKTDSKMVCDVVSRMEDTEP----------------------------------------FSAELLSAMMRLWG-DSGIQECFN-RSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVETHFTFK-NLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSN-TYEDAAAYIQTQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09471-1", "uniprot_id": "GNAO_HUMAN", "id": "P09471-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "--------------------------------------------------------------------------MGCTLS----AEERAA-------LERSK----AIEKNLKEDGI-SAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKE---------------------------------------------------------------------RKADAKMVCDVVSRMEDTEP----------------------------------------FSAELLSAMMRLWG-DSGIQECFN-RSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFK-NLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPN-TYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W442-1", "uniprot_id": "F8W442_DANRE", "id": "F8W442-1", "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "aln": "--------------------------------------------------------------------------MGCTLS----AEERAA-------LDRSK----AIEKNLKEDGI-TAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGDDVKQYKPVVYSNTIQSLAAIVRAMDTLGLEYGDKE---------------------------------------------------------------------RKADAKMVCDVVSRMEDTEP----------------------------------------YSPELLSAMIRLWS-DSGIQECFS-RAREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFK-NLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESMKLFDSICNNKWFTNTSIILFLNKKDIFGDKIRKSPLSICFPEYTGSN-TFEEAVNYIQSQYESKNKSVEKEIYSHITCATDTDNIQFVFDAVTDVIIANNLRFCGLY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16378-1", "uniprot_id": "GNAO_DROME", "id": "P16378-1", "name": "G protein alpha o subunit", "aln": "--------------------------------------------------------------------------MGCAQS----AEERAA-------AARSR----LIERNLKEDGI-QAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNE---------------------------------------------------------------------RESDAKMVFDVCQRMHDTEP----------------------------------------FSEELLAAMKRLWQ-DAGVQECFS-RSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFK-NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQ-EYGEAAAYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08539-1", "uniprot_id": "GPA1_YEAST", "id": "P08539-1", "name": "Guanine nucleotide-binding protein alpha-1 subunit", "aln": "--------------------------------------------------------------------------MGCTVSTQTIGDESDP-------FLQNKRANDVIEQSLQLEKQ-RDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFA-RSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIG-SSKFKVLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLSLNKT-NKPIYVKRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10823-1", "uniprot_id": "GPA2_YEAST", "id": "P10823-1", "name": "Guanine nucleotide-binding protein alpha-2 subunit", "aln": "MGLCASSEKNGSTPDTQTASAGSDNVGKAKVPPKQEPQKTVRTVNTANQQEKQQQRQQQPSPHNVKDRKEQNGSINNAISPTATANTSGSQQINIDSALRDRSSNVAAQPSLSDASSGSNDKELKVLLLGAGESGKSTVLQQLKILHQNGFSEQEIKEYIPLIYQNLLEIGRNLIQARTRFNVNLEPEC-------------------------------------------------------------------ELTQQDLSRTMSYEMPNNYTGQ----------------------------------------FPEDIAGVISTLWALPSTQDLVNGPNASKFYLMDSTPYFMENFTRITSPNYRPTQQDILRSRQMTSGIFDTVIDMGSDIKMHIYDVGGQRSERKKWIHCFDNVTLVIFCVSLSEYDQTLMEDKNQNRFQESLVLFDNIVNSRWFARTSVVLFLNKIDLFAEKLSKVPMENYFPDYTGGS-DINKAAKYILWRFVQLNRA-NLSIYPHVTQATDTSNIRLVFAAIKETILENTLKDSGVLQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : * .: . :.: : .*. :::*:************:::*:*::*:.**: :: :* ::: : :: :: :.:: . : * . . . : :: .: ** . .: :: * .*: *:::.: :: : :* *::***: * *:** :. : : . :::: *.**************:.:* ::* :::* *** * **: **::**: ***.: *.::* *..:***** *:* :*: . *: **:* * . *: : *:: . ** : * ****..::.*: *:.: *: :.*: *: ", "identical_positions": 97, "similar_positions": 127, "identity": "17.38%" }, { "cls_id": "homologset.agr.FB:FBgn0001123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63803-1", "uniprot_id": "GNAS1_RAT", "id": "Q63803-1", "name": "Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas", "aln": "MGMLNCLHGNNMSGQHDIPPEVGDQPEQEPLEAQGAAAPGAGVGPAEEMETEP----SNNEPIPDETDSEVCGPPEDSKSDIQSPSQAFEEVQVGGDYSPPPEEAMPFEIQQPSLGDFWPTLEQPG-PSGTPSGIKAFNPAILEPGTPTGAHPGLGAYSPPPEEAMPFEFNEPAQEDRCQPPLQVPDLAPGGP-EAWVSRALPAEPGNLGFENTGFREDYSPPPEESVPFQLDGEEFGGDSPPPGLPRVTPQIGIGGEFPTVAVPSTLCLAPAANAPPLWVQGAIGRPFREAVRSP-NFAYDISPMEITRPLLEIGRASTGVDDDTAVNMDSPPIASDGPPIEVSGAPVKSEHAKRPPLERQAAETGNSPISSTTAEEAKVPSLERGEGSPTQPETVHIKPAPVAESGTDSS--KADP--DSATHAVLQIGPEEVGGVPTMPTDLP--PASEDAGPDVRAEPDGGTAPATPAESEDNREPAAAAAAEPAAEPAAEPAAEPAAEPAAEPAAEAVPDTEAESASGAVPDTQEEPAAAAASATPAEPAARAAPVTPTEPATRAVPSARAHPAAGAVPGASAMSAAARAAAARAAYAGPLVWGARSLSATPAARASLPARAAAAARAASAARAVAAGRSASAAPSRAHLRPPSPEIQVADPPTPRPAPRPSAWPDKYERGRS-CCRYEAASGICEIESSSDESEEGATGCFQWLLRRNRRPGQPRSHTVGSNPVRNFFARAFGSCFGLSECTRSR-SLSPGKAKDPMEERRKQMRKEAMEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA------AMSNLVPPVELANPENQFRVDYILSVMNVPNFDFP-------PEFYEHAKALWE-DEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLPRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDA--------------------TPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6R0H7-1", "uniprot_id": "GNAS1_MOUSE", "id": "Q6R0H7-1", "name": "Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas", "aln": "MGMFNCLHGNNMSGQHDIPPEVGEQPEQEPLEAPGAAAPGAGAGPAEEMATEPDSEPSNNEPVPDETGSEISGPPEDSKSDIQSPCQAFEEVRVGGDYSPPPEEAMPFETQQPSLGDFWPTLEQPG-PSGTPSGLQAFNPAILEPGTPTGASPGLGAYTPPPEEAMPFEFNEPAQGDHSQPPLQVPDLAPGGP-EALVPRALPAEPGNIRFENAGFREDYSPPPEESVPFQVGGEEFGGDSPPPGLPRVIPQIGIGGEFPTVAVPSALCLAPAENAPPLWVRGAIDRPFREAVRSPPNFACDSPPMEITRPLLEIGRASIGVDDDTAVNMDSPPIASDGPPIEVSGAPDKSECAERPPVEREAAEMEGSPTT-ATAVEGKVPSPERGDGSSTQPEAMDAKPAPAAQAVSTGS--DAGAPTDSAMLTDSQSDAGEDGTAPGTPSDLQSDPEELEEAPAVRADPDGGAAPVAPATP-------------------AESESEGSRDPAAEPASEAVPATTAESASGAAPVTQVEPAAAAVSATLAEPAARAAPITPKEPTTRAVPSARAHPAAGAVPGAPAMSASARAAAARAAYAGPLVWGARSLSATPAARASLPARAAAAARAASAARAVAAGRSASAAPSRAHLRPPSPEIQVADPPTPRPPPRPTAWPDKYERGRS-CCRYEASSGICEIESSSDESEEGATGCFQWLLRRNRRPGLPRSHTVGSNPVRNFFTRAFGSCFGLSECTRSR-SLSPGKAKDPMEERRKQMRKEAIEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA------AMSNLVPPVELANPENQFRVDYILSVMNVPNFDFP-------PEFYEHAKALWE-DEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDA--------------------TPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ01-1", "uniprot_id": "A0A8M1PZ01_DANRE", "id": "A0A8M1PZ01-1", "name": "Guanine nucleotide-binding protein G(s) subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGMCHSFRSRLSESAITYTGGR----------------------------------SAAG---------AGIDAESGG-----------------------------------------------HSDSCDP-----------QLRERRR------AEERARVKAENKRSRNIDKSLKAEKREYKQTHRLLLLGAGESGKSTIVKQMRILHVNGFNAE---------------EKKQKIQDIKNNIKEAIETIVT------AMSVLVPPVQLACPANKFRIDYILNLANQKDFEFT-------TEFYEHTKTLWQ-DEGVKACFERSNEYQLIDCAQYFLDRIDTVKQSDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVLREDNQTNRLQEALNLFKNIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPDDA--------------------TPEQGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5JWF2-1", "uniprot_id": "GNAS1_HUMAN", "id": "Q5JWF2-1", "name": "Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas", "aln": "MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEP----PHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDD-TPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEG---AADAAEGGKVPSPGYG------------SPAAGAASADTAARA----------------------------------------APAAPADPDSGATPED-------------------------------------------PDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPA--------------APDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPT-RASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNR----RRRKPQRNLLRNFLVQAFGGCFGRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA------AMSNLVPPVELANPENQFRVDYILSVMNVPDFDFP-------PEFYEHAKALWE-DEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDA--------------------TPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGK7-1", "uniprot_id": "GNAL_MOUSE", "id": "Q8CGK7-1", "name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCLGNSSKTAEDQGVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPE---------------EKKQKILDIRKNVKDAIVTIVS------AMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYS-------QEFFDHVKKLWD-DEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDA--------------------TPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38406-1", "uniprot_id": "GNAL_RAT", "id": "P38406-1", "name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCLGNSSKTAEDQGVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGSNPE---------------EKKQKILDIRKNVKDAIVTIVS------AMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYS-------QEFFDHVKKLWD-DEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDA--------------------TPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38405-1", "uniprot_id": "GNAL_HUMAN", "id": "P38405-1", "name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCLGGNSKTTEDQGVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPE---------------EKKQKILDIRKNVKDAIVTIVS------AMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYS-------QEFFDHVKKLWD-DEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDA--------------------TPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IQ19-1", "uniprot_id": "A0AC58IQ19_DANRE", "id": "A0AC58IQ19-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLCYSLRPRLFGNLSGSISNANSESDHQPPDPGMMMMPSCVRGSRQRDEDSGGNDGKTSPTSPLRSGDA-------------------------GKVPAGELRRGDADRALIQNGGGGGGKRRLQ---------------------------------------------------------------------------------------------------LLQTPSSA------------QKHKNWDKLVVVEEKEAEKEAKKVSKNIDRALKELKREYKQTHRLLLLGAGESGKSTIVKQMKILHVNGFNAE---------------EKKQKIQDIRKNVKDAIVTIVS------AMSTLIPPIPLANPEDQFRIDYIKSIAPLSDFDYT-------QEFFDHAKKLWE-DEGVKACYERSNEYQLIDCAQYFLDRIDAVRQSDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNNTNRLREALALFRSIWNNRWLRTISVILFLNKQDMLAEKVLAGKSKIEDYFPDFAYYTLPDKVKKRKCVWKRKKRNGEDVSNITPDPGEDPRVTRAKFFIRDEFLKISTESGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20354-1", "uniprot_id": "GNAS_DROME", "id": "P20354-1", "name": "G protein alpha s subunit", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCFGSPTSKQSDVNSE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDS---------------EKKQKIDDIKKNIRDAILTITG------AMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYP-------PEFYEHTEELWK-DKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTG-----------------DAIMESNDDPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08539-1", "uniprot_id": "GPA1_YEAST", "id": "P08539-1", "name": "Guanine nucleotide-binding protein alpha-1 subunit", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTG--RAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKS--MPIRKYFPDYQGRVGDAEAG------------------------------------LKYFEKIFLSLNKTNKPIYVKRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: * : :: * :.*. :* * :::: : : : . :: :: :::.: *:. * : :: : : ::: :: . : **. *:*: : ****:** ..* *:::.:. . :*. .::*: : *: *:** **.*::.. :*:::*.****.**:***:**:.:**:::* * *.*: :: ** **::*:: ** .: *.:*:: ..****** *:: **: : : .**.:: .. . * :* .. .: * : ***.**:.:: *:. *:* : :*:: ::", "identical_positions": 79, "similar_positions": 131, "identity": "6.62%" }, { "cls_id": "homologset.agr.FB:FBgn0001124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23542-1", "uniprot_id": "AATC_YEAST", "id": "P23542-1", "name": "Aspartate aminotransferase, cytoplasmic", "aln": "-------------------MSATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIHNDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDAFQEDRVISVQSLSGTGALHISAKFFSKFFP-----DKLVYLSKPTWANHMAIFENQGLKTAT-YPYWANETKSLDLNGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVSNPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKLGTPGNWDHIVNQCGMFSFTGLTPQMVKRLEETHAVYLVASGRASIAGLNQGNVEYVAKAIDEVVR------FYTIEAKL-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZAA5-1", "uniprot_id": "A1ZAA5_DROME", "id": "A1ZAA5-1", "name": "Aspartate aminotransferase, cytoplasmic", "aln": "MFIILKRLNYPGLLQNFQLSTMSIYADVPKGPAIEVFALTQAFKDDSNPNKVNLSVGAYRTDAGVPWVLPVVRKTEISIASDEQVNHEYLPVTGLETFTNAATELVLGADSPAIKENRAFGVQTISGTGALRVAADFLHTQLN-----RNVVYYSNPTWENHHKIFCDAGFTTVKSYRYWDQNKRELDFKNMLADLNDAPPGAVIILHACAHNPTGIDPTQEQWTELADLMEKKKLFPLFDSAYQGFASGDPDRDAWAARYFVQRG---FELFICQSFAKNFGLYCERTG--NLAVVQ--KNGATKAAVHSQLTLLIRGQYSNPPAYGARIVSKVLNTPELRKEWMASIQAMSSRIREMRTALRDKLVALGTPGTWDHIVNQIGMFSYTGLNESHVRVLIDQYHIYLLKTGRISMSGLNKGNVEYVAKAIHAAVTGSGESASCPCENKL-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05201-1", "uniprot_id": "AATC_MOUSE", "id": "P05201-1", "name": "Aspartate aminotransferase, cytoplasmic", "aln": "------------------MAPPSVFAQVPQAPPVLVFKLTADFRDDPDPRKVNLGVGAYRTDESQPWVLPVVRKVEQKIANDNSLNHEYLPILGLAEFRSCASRLVLGDNSLAIRENRVGGVQSLGGTGALRIGADFLGRWYNGTDNKNTPIYVSSPTWENHNAVFSAAGFKDIRPYCYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTPEQWKQIAAVMQRRFLFPFFDSAYQGFASGDLEKDAWAIRYFVSEG---FELFCAQSFSKNFGLYNERVG--NLTVVG--KESDSVLRVLSQMEKIVRITWSNPPAQGARIVAATLSDPELFKEWKGNVKTMADRILTMRSELRARLEALKTPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINMCGLTTKNLDYVATSIHEAVT--------KIQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13221-1", "uniprot_id": "AATC_RAT", "id": "P13221-1", "name": "Aspartate aminotransferase, cytoplasmic", "aln": "------------------MAPPSFFAQVPQAPPVLVFKLIADFRDDPDPRKVNLGVGAYRTDDSQPWVLPVVRKVEQKIANDHSLNHEYLPILGLAEFRSCASQLVLGDNSPALRENRVGGVQSLGGTGALRIGADFLGRWYNGTDNKNTPVYVSSPTWENHNGVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTEEEWKQIAAVMKRRFLFPFFDSAYQGFASGDLEKDAWAIRYFVSEG---FELFCAQSFSKNFGLYNERVG--NLTVVG--KEHDSVLRVLSQMEKIVRITWSNPPAQGARIVATTLSNPELFKEWKGNVKTMADRILTMRSELRARLEALKTPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLMPSGRINMCGLTTKNLDYVATSINEAVT--------KFQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17174-1", "uniprot_id": "AATC_HUMAN", "id": "P17174-1", "name": "Aspartate aminotransferase, cytoplasmic", "aln": "------------------MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEG---FEFFCAQSFSKNFGLYNERVG--NLTVVG--KEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVT--------KIQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TSV6-1", "uniprot_id": "AATC2_MOUSE", "id": "Q7TSV6-1", "name": "Aspartate aminotransferase, cytoplasmic 2", "aln": "------------------MTSLSVFRDVPTAQKLEG-SLLKIYRQDGYPSKLFLAYKVCMTEEGHPWVSLVVHKTRLQIAEDPSLDYEYLPLVGLKSFIQSSLELLFGKHSEAIAEKRVGGVHIVGESGAFQLGAQFLKTWRKN----VKIVCIVSCQKEQCGLIFQDMGF-IVYEYSIWNASDLCSDPSMFVEVLQHIPVGSILVIG----NITDCKFTQNQWTKLMSIIKSKQIFPFFDIPCQGLSTGDLEEDTKILQYFVSLG---LEFFCSQSLSKNFGIYDEGVG--ILVVAA--LSNQHLLCVLSQLMDYVQALWGNPPATGARIITSILCNPALFGEWKQSLKGVVENMMLIKEKVKEKLRLLGTPGSWDHITRQSGTHGYLGLTYQQVEFLVKKKHIYLPKTSRINFTCINARNIDYITQSIHEAVMLTEG-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LWJ8-1", "uniprot_id": "A0ABK0LWJ8_RAT", "id": "A0ABK0LWJ8-1", "name": "Putative aspartate aminotransferase, cytoplasmic 2", "aln": "------------------MTSLSVFRDVPIAQKLEG-SLLKIYRQDDSSVKMFLAYKVCMTEGGHPWVSLVVRKTRLQIAEDPSLNYEYLPLAGLKSFIQASLELLFGKHSQAIVEKRVGGVHIVGESGAFQLGAQFLKIWRKN----LKTVCIISCQNEQCGLIFRDMGF-TVYEYSVWNSTDLCSDPSIFVEVLQHIPAGSILVIG----NISDCRFTQNQWTKLMSIIKSKQIFPFFDIPCQGLSTGDLEEDSKFLQHFVSLG---FEFFCSQSLSKNFGIYDEGVG--ILVVAA--LSNQHLLCVISQLMDYVQALWGNPPATGARIITSILCNPALFGEWKQSLKGVVENIMLIKEKVKEKLRLLGTPGSWNHITRQSGTHGYLGLNCILRGLFPK-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NHS2-1", "uniprot_id": "AATC2_HUMAN", "id": "Q8NHS2-1", "name": "Aspartate aminotransferase, cytoplasmic 2", "aln": "------------------MPTLSVFMDVPLAHKLEG-SLLKTYKQDDYPNKIFLAYRVCMTNEGHPWVSLVVQKTRLQISQDPSLNYEYLPTMGLKSFIQASLALLFGKHSQAIVENRVGGVHTVGDSGAFQLGVQFLRAWHKD----ARIVYIISSQKELHGLVFQDMGF-TVYEYSVWDPKKLCMDPDILLNVVEQIPHGCVLVMG----NIIDCKLTPSGWAKLMSMIKSKQIFPFFDIPCQGLYTSDLEEDTRILQYFVSQG---FEFFCSQSLSKNFGIYDEGVG--MLVVVA--VNNQQLLCVLSQLEGLAQALWLNPPNTGARVITSILCNPALLGEWKQSLKEVVENIMLTKEKVKEKLQLLGTPGSWGHITEQSGTHGYLGLNSQQVEYLVRKKHIYIPKNGQINFSCINANNINYITEGINEAVLLTESSEMCLPKEKKTLIGIKL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: :: : : :* . *: *. . : *** *: .. * .* . ::*** ** : . : : :* .* *: *.*. .*: :. :**:::...*: : . :* *: * * * . :: ::. * .:.:: * . * . * :: : : :.:** . **: :.: :.*: : *. .* .**::** *:* * .* *.:. . * **: : *** **:::: * * * :* .: : ..: : :: :* * ***.*.**. * * ..: **. : ", "identical_positions": 72, "similar_positions": 111, "identity": "15.79%" }, { "cls_id": "homologset.agr.FB:FBgn0001125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00507-1", "uniprot_id": "AATM_RAT", "id": "P00507-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALLHSGRVLSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE---AQIAGKNLDKEYLPIGGLADFCKASAELALGENSEVL-----KSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQS---------VLLLHACAHNPTGVDPRPEQWKEMAAVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTVVCKDAEE-------------AKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05202-1", "uniprot_id": "AATM_MOUSE", "id": "P05202-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALLHSSRILSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE---AQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVL-----KSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQS---------VLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTVVCKDAEE-------------AKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00505-1", "uniprot_id": "AATM_HUMAN", "id": "P00505-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE---AQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEVL-----KSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQS---------VLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTMVCKDADE-------------AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJR0-1", "uniprot_id": "A0A8I6GJR0_RAT", "id": "A0A8I6GJR0-1", "name": "Aspartate aminotransferase", "aln": "-MALLHSR-----MATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQR---PRLLEKIWTKNAYPSG----------------------------DWLVFVRLLQ-----RSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQS---------VLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGIN------VCLCQSYAKNMGLYGERVGSFTVVCKDEEE-------------AKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMF------------------FYMIKDGRISVAGVTSGNVCYLTHAIHQVTK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7SYK7-1", "uniprot_id": "AATM_DANRE", "id": "Q7SYK7-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "-MALFKSSKILSSVGSQTP--VLAVLQLRASSWWTEVQMGPPDPILGVTEAFKRDTNPKKMNLGVGAYRDDQGKPFVLSSVRKAE---AQIAAKKLDKEYLPIGGLADFSKACVQLALGPDNEVL-----KSGRSITVQTISGTGSLRIGANFVSRFHNASRDVYLPKPSWGNHTPVFRDAGMQLKAYTYYEPKTCGFNLKGALDDISKIPEKS---------VILLHACAHNPTGVDPRPEQWKEMAALIKKRNLLVFFDMAYQGFASGDIDRDAWAVRYFIEQGHN------ILLSQSFAKNMGLYGERVGGFTVVCKDAEE-------------AKRVESQLKILIRPIYSNPPMNGARIAATILNTPELYKEWLQEVKGMADRIIRMREMLVSNLKKEGSTHNWQHVTDQIGMFCFTGLKPEQVERLINEFSIYMTKDGRISVAGVTSANVEYLAHAIHAVTK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPY3-1", "uniprot_id": "Q8IPY3_DROME", "id": "Q8IPY3-1", "name": "Aspartate aminotransferase", "aln": "MSRTIIMTLKDIVHVWSNDPGERMCRANRVSTWFSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAE---KRVVSRSLDKEYATIIGIPEFYNKAIELALGKGSKRL-----AAKHNVTAQSISGTGALRIGAAFLAKFWQGNREIYIPSPSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKS---------IVLLHACAHNPTGVDPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHD------FCLAQSFAKNMGLYGERAGAFTVLCSDEEE-------------AARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRIIDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSKNVEYLAESIHKVTK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01802-1", "uniprot_id": "AATM_YEAST", "id": "Q01802-1", "name": "Aspartate aminotransferase, mitochondrial", "aln": "--------------MLRTRLTNCSLWRPYYTSSLSRVPRAPPDKVLGLSEHFKKVKNVNKIDLTVGIYKDGWGKVTTFPSVAKAQKLIESHLELNKNLSYLPITGSKEFQENVMKFLFKESCPQFGPFYLAHDRISFVQTLSGTGALAVAAKFLALFIS--RDIWIPDPSWANHKNIFQNNGFEN-IYRYSYYKDGQIDIDGWIEQLKTFAYNNQQENNKNPPCIILHACCHNPTGLDPTKEQWEKIIDTIYELKMVPIVDMAYQGLESGNLLKDAYLLRLCLNVNKYPNWSNGIFLCQSFAKNMGLYGERVGSLSVITPATANNGKFNPLQQKNSLQQNIDSQLKKIVRGMYSSPPGYGSRVVNVVLSDFKLKQQWFKDVDFMVQRLHHVRQEMFDRLG----WPDLVNFAQQHGMFYYTRFSPKQVEILRNNYFVYLTGDGRLSLSGVNDSNVDYLCESLEAVSKMDKLA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.* .*** :**::* **: .* :*::* . *:*. : :.*: . . . . .: :. . * : . : : *. . . . . ::: * ::::. :. :. ::****.*** *:** *:*.:: : : .: :.******: :*: :** :: . . *.**:**********.*.:::: : .: **:* ::* :**.** *:*:. :*. .* :*:::*. *.:*: * : ..* : :..:* *** .*: ***:*::**.. ** ** .::. *:* ", "identical_positions": 88, "similar_positions": 122, "identity": "18.64%" }, { "cls_id": "homologset.agr.FB:FBgn0001128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35077-1", "uniprot_id": "GPDA_RAT", "id": "O35077-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------------------------------------MAGKKVCIVGSGNWGSAIAKIVGSNASQL-AHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGIDEGPNG-LKLISEVIGESLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQG---------QLLKELMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGS-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFICCLQNHPEHM----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13707-1", "uniprot_id": "GPDA_MOUSE", "id": "P13707-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------------------------------------MAGKKVCIVGSGNWGSAIAKIVGSNAGRL-AHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAIPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGVDEGPNG-LKLISEVIGERLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQG---------QLLKDLMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGT-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFIRCLQNHPEHM----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21695-1", "uniprot_id": "GPDA_HUMAN", "id": "P21695-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "--------------------------------------------------------------------------------MASKKVCIVGSGNWGSAIAKIVGGNAAQL-AQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVDEGPNG-LKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQG---------QLLKELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGP-VSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ULJ0-1", "uniprot_id": "GPD1L_MOUSE", "id": "Q3ULJ0-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSNVKTL-QKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIHKICDEITGRVPEKALGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVMQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFAKIFCKGQ-VSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAP9-1", "uniprot_id": "D3ZAP9_RAT", "id": "D3ZAP9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSNVKNL-QKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLGEAVQDADLLVFVIPHQFIHKICDEITGRVPKKAVGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVLQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLCCGDNTKAAVIRLGLMEMIAFAKIFCKGQ-VSTATFLESCGVADLITTCYGGRNRKVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N335-1", "uniprot_id": "GPD1L_HUMAN", "id": "Q8N335-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKL-QKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEG-LKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQ-VSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZKP8-1", "uniprot_id": "A0A8I5ZKP8_RAT", "id": "A0A8I5ZKP8-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "------------------------------------------------------------------------------MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQ-QKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRG-LMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNG---------ILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQ-VSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ALX9-1", "uniprot_id": "A0A8I6ALX9_RAT", "id": "A0A8I6ALX9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "-----------------------------MTHYTRVVNVFFKQVGRQAGQGTSRLDQIDGGQQLAEKAPSPQQDIGLKVLPGPLKVSIVGSGNWASAVSKIIGNNVKTT-KKFASPVKMWVFEEIVNGRKLTDIINTDHENVKYLPGYRLPENVIATPSLSQAVQDADLLVFAFPHQFIRKICDELAEVVPRKARGLTLIKGIDEGPES-LKLISDIIREKVNIDVSVLMGANLANEVAAEQFCETTIGSKVLQNG---------LLFKELFQTPNFRVTVVEDPDTVELCGALKNIVAMGSGFCDSFCCGNSTKAAVIRLGLMEMISFVRTFSKGQ-VSIATFLESCGVADLISTCYGGRNRKVAEAFARTGKSLEELEKEMLKGQKLQGPHTSAQVYRILKQKGLLDKFPLFTVVYQICYEGRAVTELIPCLQNHPEHRRRELGTSPALPHPSQGHTDTRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XIZ6-1", "uniprot_id": "GPD1L_DANRE", "id": "Q5XIZ6-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "-------------------------------------------------------------------------------MAAPLKVCIVGSGNWGSAIARIIGSNAQKL-QCFATTVKMWVYEEMVNGKKLSEIINTEHENVKYLPGYKLPENVVAVPQLRDAADGADLLVFVVPHQFIRKLCDEMMGCVSERARGITLIKGIDEGPEG-LKLISDIIREKMGIDVSVLMGANIANEVAAEKFCESTIGSKVLENG---------LLFKDLLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLQCGDNTKAAVIRLGLMEMIAFAKLFSKDDSVSSATFLESCGVADLITTCYGGRNRRVAEAFAKTGKSIEELEKEMLNGQKLQGPLTSAEVYHILKQKGLVEKFPLFTAVYQICFEDKPVRDMITCLQSHPEHL----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13706-3", "uniprot_id": "GPDA_DROME", "id": "P13706-3", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "-------------------------------------------------------------------------------MADKVNVCIVGSGNWGSAIAKIVGANAAAL-PEFEERVTMFVYEELIDGKKLTEIINETHENVKYLKGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYG---------KVLRDLFQANHFRVVVVDDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGS--KLSTFFESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLFTAIHKICTNQLKPNDLIDCIRNHPEHMDTSIMPSPKL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41911-1", "uniprot_id": "GPD2_YEAST", "id": "P41911-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial", "aln": "MLAVRRLTRYTFLKRTHPVLYTRRAYKILPSRSTFLRRSLLQTQLHSKMTAHTNIKQHKHCHEDHPIRRSDSAVSIVHLKRAPFKVTVIGSGNWGTTIAKVIAENTELHSHIFEPEVRMWVFDEKIGDENLTDIINTRHQNVKYLPNIDLPHNLVADPDLLHSIKGADILVFNIPHQFLPNIVKQLQGHVAPHVRAISCLKGFELGSKG-VQLLSSYVTDELGIQCGALSGANLAPEVAKEHWSETTVAYQLPKDYQGDGKDVDHKILKLLFHRPYFHVNVIDDVAGISIAGALKNVVALACGFVEGMGWGNNASAAIQRLGLGEIIKFGRMFFPES-KVETYYQESAGVADLITTCSGGRNVKVATYMAKTGKSALEAEKELLNGQSAQGIITCREVHEWLQTCELTQEFPLFEAVYQIVYNNVRMEDLPEMIEELDIDDE---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q00055-1", "uniprot_id": "GPD1_YEAST", "id": "Q00055-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 1", "aln": "------------------------------------------------MSAAADRLNLTSGHLNAGRKRSSSSVSLKAAEK-PFKVTVIGSGNWGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRHQNVKYLPGITLPDNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISCLKGFEVGAKG-VQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEGKDVDHKVLKALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQRVGLGEIIRFGQMFFPES-REETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEKELLNGQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLHED---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ::* .*.:::::::. * * * *:* :* :...:*::*** *:***** . ** *::* ..: .: ..*:::* ****: .: .:: : .. .: ::..: . . : *:* : : : ..* *** * *** .:.*:*:. ::: *:: * : *::: :.:.****::** . .* :.: *:.:.**: *:** *:* * * : : **.*.*: *: * * : : : : ** : :**:*:**. ** *. : *. .**** .:::: : :: :.. . ", "identical_positions": 83, "similar_positions": 125, "identity": "17.93%" }, { "cls_id": "homologset.agr.FB:FBgn0001134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14867-1", "uniprot_id": "GBRA1_HUMAN", "id": "P14867-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-1", "aln": "------------------------------------MRKSPGLSDCLWAWILL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LST--LTGRSYGQPS------------------LQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVD-------------------------------------------------------------------------SGIVQSST---GEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG------------------------------------------------------------------------YAWDGKSV--VPEKPKKVKDPLIKKNNTY-APTATSYTPNLARG------------DPGLATIAKSATIEPK----------EVK--PETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAP--TPHQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ALU6-1", "uniprot_id": "A0A8M3ALU6_DANRE", "id": "A0A8M3ALU6-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-1", "aln": "-------------------------MDYERGFILRRMMWGGRGAAWLWIWACL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVTNALAGKSSSQN--------------------ADEQKDNTTVFTRILDSLLDGYDNRLRPGLGERVTEVKTDIFVTSIGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMAVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEEGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYVWTRGAAQSVVVADDGSRLNQYDLMGQSVD-------------------------------------------------------------------------SGVVQSST---GEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG------------------------------------------------------------------------YAWDGKSV--VPEKQKKKKESLLKKNNTYTAATATAFAPNIAR-------------DPGLATIAKSAPPPPT----------EPKEEPKPKPPEAKKTFNSVSKIDRIARIAFPLLFGTFNLVYWATYLNKKPKLQGMNLQPH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47869-1", "uniprot_id": "GBRA2_HUMAN", "id": "P47869-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-2", "aln": "------------------------------------MKTKLNIYNMQFLLFVF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVWD--PARLVLANI------------------QEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIG-------------------------------------------------------------------------KETIKSST---GEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG------------------------------------------------------------------------WAWDGKSV--VNDK-KKEKASVMIQNNAYAVAVAN-YAPNLSK-------------DPVLSTISKSATTPEP----------NKK--PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVLGVS---P--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34903-1", "uniprot_id": "GBRA3_HUMAN", "id": "P34903-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-3", "aln": "-------------------------------MIITQTSHCYMTSLGILFLINI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVG-------------------------------------------------------------------------TEIIRSST---GEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRS------------------------------------------------------------------------WAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAK-------------DTEFSTISKG-AAPSASSTPT--IIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20236-1", "uniprot_id": "GBRA3_RAT", "id": "P20236-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-3", "aln": "-------------------------------MITTQMWHFYVTRVGLLLLISI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKAEVIYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVG-------------------------------------------------------------------------TEIIRSST---GEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRS------------------------------------------------------------------------WAWEGKKVPEALEMKKKTPAAPTKKTSTTFNIVGTTYPINLAK-------------DTEFSTISKAAAAPSASSTPT--VIASPKTTYVQDSPAETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19969-1", "uniprot_id": "GBRA5_RAT", "id": "P19969-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-5", "aln": "--------------------------------MDNGMLSRFIMTKTLLVFCIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLSSHFGFSQMPTS----------------SVQD-ETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVG-------------------------------------------------------------------------TENISTST---GEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG------------------------------------------------------------------------WAWDGKKALEAAKIKKKERELILNKSTNAFTTGKLTHPPNIPK-------------EQLPGGTGNAVGTASIR------------ASEEKTS-ESKKTYNSISKIDKMSRIVFPILFGTFNLVYWATYLNREPVIKGATSPK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHJ7-1", "uniprot_id": "GBRA5_MOUSE", "id": "Q8BHJ7-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-5", "aln": "--------------------------------MDNGMLSRFIMTQTLLVFCIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLSSHFGFSQMPTS----------------SVQD-ETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVG-------------------------------------------------------------------------TENISTST---GEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG------------------------------------------------------------------------WAWDGKKALEAAKIKKKERELILNKSTNAFTTGKLTHPPNIPK-------------EQPPAGTANAP-TVSIK------------ASEEKTA-ESKKTYNSISKIDKMSRIVFPILFGTFNLVYWATYLNREPVIKGATSPK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31644-1", "uniprot_id": "GBRA5_HUMAN", "id": "P31644-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-5", "aln": "--------------------------------MDNGMFSGFIMIKNLLLFCIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLSSHFGFSQMPTS----------------SVKD-ETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVG-------------------------------------------------------------------------TENISTST---GEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG------------------------------------------------------------------------WAWDGKKALEAAKIKKK-REVILNKSTNAFTTGKMSHPPNIPK-------------EQTPAGTSNTT-SVSVK------------PSEEKTS-ESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QE70-1", "uniprot_id": "E9QE70_DANRE", "id": "E9QE70-1", "name": "", "aln": "--------------------------------MGYGPHCSGKMR-SLWVGVLF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLTCHLSLSQSTTG----------------TPKESELNDNITVFTRILDGLLDGYDNRLRPGLGEKVTEIKTNIFVTSFGPVSDTEMEYTIDVFFRQSWKDERLCFKGPMEMLPLNNLLASNIWTPDTFFLNGKKSIAHNMTTPNKLLRLKDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPISEVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAG-------------------------------------------------------------------------TEDISTSR---GQYTVMMAHFYLKRKIGYFVIQTYMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRS------------------------------------------------------------------------WAWDGKKALEAQQPKKK-DPLALSKKPNNFTA-------NINK-------------DAAISTISNST-TVQLK------------SAEAKPAPDPKKTYNSVSKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q16445-1", "uniprot_id": "GBRA6_HUMAN", "id": "Q16445-1", "name": "Gamma-aminobutyric acid receptor subunit alpha-6", "aln": "------------------------------------------MASSLPWLCII-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LWLENALGKLEVEGN---------------------FYSENVS---RILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVS-------------------------------------------------------------------------SETIKSNT---GEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQ------------------------------------------------------------------------TQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRIT------------SLSLPIVSSSEANKVLTR-------APILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24352-1", "uniprot_id": "GBRAL_DROME", "id": "Q24352-1", "name": "Gamma-aminobutyric acid receptor alpha-like", "aln": "MCTMPATRDASGSGDASTDLIAARSLSSHQGQRSNLRIFKLLISCCLLMLCIYPNAWPWSIGPGSGPFS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSADSIKGRGDTHRLG-----EMGTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERP-PVAIAED-MKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAA------------AAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRSSRILANTPDAST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ES14-1", "uniprot_id": "GBRE_RAT", "id": "Q9ES14-1", "name": "Gamma-aminobutyric acid receptor subunit epsilon", "aln": "--------------MLPKVLLMLLNMFLALQWRV-GPHIKLENKPPAQDKVVFGPQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSGKKLPARETELTAD----------------HTTERPRGKLTRASQILNTILSNYDHKLRPSIGEKPTVVTVKVFVNSLGPISILDMEYSIDIIFYQTWYDERLRYNDTFETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALIHKDGKVLYTVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDEHEMIYKW--ENFKLKIDAKNTWKLLEFDFTGVNNK-------------------------------------------------------------------------TEIISTPV---GDFMVMTFFFNVSRRFGFIVFQNYIPSSVTTMLSWVSFWIKIEAAAARASVGVSSVLTMATLGTFSRKNFPRVSYLTALDFYIAICFVLCFCTLLEFTVLNFLTYNNIERQASPKFYQFP-----------------------------------------------------------TNSRANARTRARARTRARARARARQQQEVFVCEIVTYEENAEEG-----YQWSPRSRRPQCPWRRCGRSYVC--FRVLRKYFCMVPGCEGNNWQRGRICIHVYRLDNYSRVLFPITFFFFNVVYWVICLNL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AMW3-1", "uniprot_id": "A2AMW3_MOUSE", "id": "A2AMW3-1", "name": "Gamma-aminobutyric acid receptor subunit epsilon", "aln": "--------------MLPKVLLMLLNMFLALQWRV-GPHVNLENKPPAQDKVVFGPQPQPVPQPLTPPESPAGDTVVFGPQPQPQAESPGHDDVVFSSQPQPMPQPQPMPEPQPQPEPEPEPQPQPQPQPLAGRQPLPQPLPWPMPQPQPEPEPEPEPEPEPEPEPEPEPEPEPEPQPEPQPQPLAGRQPLPQPLPWPLPLPLPEPQPEPQPDPQPEPQPEPQPEPQPEPQPEPQTPGQVQAGRQPRPRPQPEPQPQPEPQPEPQPEPQPQPEPEPEPQPEPEPQPEPEPQPEPQPEPQPEPKPEPEPQPEPEPQPEPQPEPQPEPQPEPKPEPEPQPEPKPEPEPQPEPEPEPEPEPEPQPEPEPKPEPQPEPEPEPEPEPEPEPEPEPEPEPEPEPESESELDLEPEPEPHPHPHPHPHPHPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEMKSEPQSQLEPQPSGKKLPAKEPELTVD----------------CMTERPGGKLTRASRILNTILSNYDHKLRPGIGEKPTVVTVEVIVNSLGPISTPDMEYSIDIIFHQTWYDERLRYNDTFETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALIHKDGKVLYSVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDDSEMIYKW--ENFKLEINAKNTWKLLEFDFTGVNNK-------------------------------------------------------------------------TEIISTPF---GDFMVMTFFFNVSRRFGFIVFQNYVPSSVTTMLSWVSFWIKIEAAAARASVGVSSVLTMATLGTLSCKNFPRVSYLTALDFYIAICFVLCFCTLLEFAVLNFLTYNNIKRQASLKVYQLP-----------------------------------------------------------TNSRANARTRARARTRARARARARQQQEVFVCEIVTYEENAEEG-----YQWSPRSRRPQCPWRRCGRSYVC--FRVLRKYFCMAPGCEGGSWQRGRICIHVYRLDNYSRVLFPITFFFFNVLYWLICLNL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78334-1", "uniprot_id": "GBRE_HUMAN", "id": "P78334-1", "name": "Gamma-aminobutyric acid receptor subunit epsilon", "aln": "--------------MLSKVLPVLLGILLILQSRVEGPQTESKNEASSRD-VVYGPQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLENQLLSEETKSTET----------------ETGSR-VGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKW--ENFKLEINEKNSWKLFQFDFTGVSNK-------------------------------------------------------------------------TEIITTPV---GDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQTKAHASPKLRHPR-----------------------------------------------------------INSRAHARTRARS------RACARQHQEAFVCQIVTTEGSDGEERPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYSRVVFPVTFFFFNVLYWLVCLNL-------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .:*: :* .**: :**.:* : : ..: * *:**:* :* *::* * *.* *:** : .. * * : :.:* ***:* *.*:: : :* **:: : .:* :**: *:*: * *.:.: **** : ***.*.*:.* :: * * : * ::.: . . : .:: :: * :.*::* . :* * *. : .:** ****:: *:.. *. .*:::****: *. : .:*:*:* **:*::: :.: : *.::::*:.::: . ::*. :*: **: * :*:.** :. ", "identical_positions": 89, "similar_positions": 127, "identity": "8.06%" }, { "cls_id": "homologset.agr.FB:FBgn0001138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09100-1", "uniprot_id": "GATA2_MOUSE", "id": "O09100-1", "name": "Endothelial transcription factor GATA-2", "aln": "----------MEVAPEQPRWMAHP----------AVLNAQHPDSHHPG--LAHNYMEP-AQLLPPDEVDVFFNHLDSQGNP--YYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAA--GGSGGGSGSSVASLTPTAAHSGSHLFGFP-PTPPKEVSPDPSTTGAASPASSSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYGSSLFHPGGFLGGPASSFTPKQRSKARSCSE------GRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTCCANCQTTT----TTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCM-----QEKSPPF-SAAALAGHMAPVGHLPPFSHSGHILPTP-------TPIHPSSSLSFGHPHPSSMVTAMG---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924Y4-1", "uniprot_id": "GATA2_RAT", "id": "Q924Y4-1", "name": "Endothelial transcription factor GATA-2", "aln": "----------MEVAPEQPRWMAHP----------AVLNAQHPDSHHPG--LAHNYMEP-AQLLPPDEVDVFFNHLDSQGNP--YYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAA--GGSGGGSGSSVASLTPTAAHSGSHLFGFP-PTPPKEVSPDPSTTGAASPASPSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLAPMGTQPATHHPIPTYPSYVPASAHEYGSGLFHPGGFLGGPASSFTPKQRSKARSCSE------GRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTCCANCQTTT----TTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCM-----QEKSSPF-SAAALAGHMAPVGHLPPFSHSGHILPTP-------TPIHPSSSLSFGHPHPSSMVTAMG---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23769-1", "uniprot_id": "GATA2_HUMAN", "id": "P23769-1", "name": "Endothelial transcription factor GATA-2", "aln": "----------MEVAPEQPRWMAHP----------AVLNAQHPDSHHPG--LAHNYMEP-AQLLPPDEVDVFFNHLDSQGNP--YYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAG--GGSGGGSGSSVASLTPTAAHSGSHLFGFP-PTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSE------GRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTCCANCQTTT----TTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCM-----QEKSSPF-SAAALAGHMAPVGHLPPFSHSGHILPTP-------TPIHPSSSLSFGHPHPSSMVTAMG---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXB8-1", "uniprot_id": "A0A8M3AXB8_DANRE", "id": "A0A8M3AXB8-1", "name": "", "aln": "----------MEVAADQSRWMAHHH---------AVLNGQHPESHHHG--LTHNYMEPMAPLLPPDEVDVFLNHLDSQGNP--YYSN---SRARVSYGQAHARLTGSQVCRPHLIHSPGIPWLDSGKAALSAA---HHNAWAVSHFSKPGLHPASAAYP--------------CSSSSSTAPVSSLTSATHSSPHPLYNFP-PTPPKDVSPDP---GPSSPTS-----TTARMDEKESIKYQVSIADGMKMEGCSPLRGSLAMSAQTPSTHHPIPTYPTYSLPAPHDYGGGLFHPGTLLSGSASSFTPKCKSKTRSCSEF--CTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTCCANCQTTT----TTLWRRNGNGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKRSKRSGEGFEELSKCM-----QDKTSPFGSASALASHMPHMGHLPPFSHSGHMLPTP-------TPIHP----TFSHPHHSGRSPAWAEPH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23772-1", "uniprot_id": "GATA3_MOUSE", "id": "P23772-1", "name": "Trans-acting T-cell-specific transcription factor GATA-3", "aln": "----------MEVTADQPRWVSHHHP--------AVLNGQHPDTHHPG--LGHSYMEA-QYPLT-EEVDVLFNIDGQGNHVPSYYGNS--VRATVQRYPPTH--HGSQVCRPPLLHG-SLPWLDGGKALSSHH---TASPWNLSPFSKTSIHHGSPGPL------------------SVYPPASSSSLAAGHSSPHLFTFP-PTPPKDVSPDPSLSTPGSAGS-------ARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTE------GRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTSCANCQTTT----TTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPK----------SSSF-NPAALSRHMSSLSHISPFSHSSHMLTTP-------TPMHPPSGLSFGPHHPSSMVTAMG---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23771-1", "uniprot_id": "GATA3_HUMAN", "id": "P23771-1", "name": "Trans-acting T-cell-specific transcription factor GATA-3", "aln": "----------MEVTADQPRWVSHHHP--------AVLNGQHPDTHHPG--LSHSYMDAAQYPLP-EEVDVLFNIDGQGNHVPPYYGNS--VRATVQRYPPTH--HGSQVCRPPLLHG-SLPWLDGGKALGSHH---TASPWNLSPFSKTSIHHGSPGPL------------------SVYPPASSSSLSGGHASPHLFTFP-PTPPKDVSPDPSLSTPGSAGS-------ARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVP----EYSSGLFPPSSLLGGSPTGFGCKSRPKARSST-------GRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTSCANCQTTT----TTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPK----------NSSF-NPAALSRHMSSLSHISPFSHSSHMLTTP-------TPMHPPSSLSFGPHHPSSMVTAMG---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91428-1", "uniprot_id": "GATA3_DANRE", "id": "Q91428-1", "name": "Transcription factor GATA-3", "aln": "----------MEVSPEQHRWVTHHT------------VGQHPETHHPG--LGHSYMDPSQYQLA-EDVDVLFNIDGQSNHP--YYGNP--VRA-VQRYPPPP--HSSQMCRPSLLHG-SLPWLDGGKSIGPHH---STSPWNLGPFPKTSLHHSSPGPL------------------SVYPPASSSSLSAGHSSPHLFTFP-PTPPKDVSPDPAISTSGSGSS-------VRQEDKECIKYQVSLAESMKLDSAHSR-SMASIGAGASSAHHPIATYPSYVP----DYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSE------GRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPK------RRL------SAARRAGTSCANCQTTT----TTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKSHDSMEDFSKSL-----MEKNSSF-SPAALSRHMTSFP---PFSHSGHMLTTP-------TPMHPSSSLPFASHHPSSMVTAMG---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91623-1", "uniprot_id": "GATAC_DROME", "id": "P91623-1", "name": "GATA-binding factor C", "aln": "------MDMTSTAEAAARSWYDSPRLGGGGSSGGGNGGGVSPQTNGLG--SAGSSLAHSHHSLS-SGASSAGSSVGVGSALGGGGGSGLDTSDMSAFYALESNGHHRRYYPSYHQHTSRMPSTHASPQVCRPHFHTPLSPWLTSEHKSFAPASAWSMGQFACPQ---------EPQVEHKLGQMGQSHQTTAAGQHSFPFP-PTPPKDSTPDSVQTGPS--------------------EYQAVMNAFMHQQATGSTSLTDASCALDIKPS---------------------IQNGSASGSSGSGTTHTSTPKQREEGR--------ECVNCGATSTPLWRRDGTGHYLCNACGLYYKMNGQNRPLIKPK------RRLTLQSLQSAAKRAGTSCANCKTTT----TTLWRRNASGEPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKLSSKSKKKKGLGGGCLPIGGHLGMGDFKPLDPSKGFGGGFSASMAQHGHLSSGLHPAHAHMHGSWYTGGMGALGASSGLQGGFSTAGSLSGAVVPHSQPYHLGLSSMGTWRTDYT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43574-1", "uniprot_id": "GAT1_YEAST", "id": "P43574-1", "name": "Transcriptional regulatory protein GAT1", "aln": "----MHVFFPLLFRPSPVLFIACAYIY-------IDIYIHCTRCTVVN--ITMSTNRVPNLDPDLNLNKEIWDLYSSAQKILPDSNRILNLSWRLHNRTSFHRINRIMQHSNSIMDFSASPFASGVNAAGPGNNDLDDTDTDNQQFFLSDMNLNGSSVFENVFDDDDDDDDVETHSIVHSDLLNDMDSASQRASHNASGFP-NFLDTSCSSSFDDHFIFTNNLPFLNNNSINNNHSHNSSHNNNSPSIANNTNANTNTNTSASTNTNSPLLRRNPSPSIVKPGSRRNSSVRKKKPALKKIKSSTSVQSSATPPSNTSSN-----PDIKCSNCTTSTTPLWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDII---K--------KRQRSSTKINNNITPPP----SSSLNPGAAGKKKNYTASVAASKRKNSLNIVAPLKSQDIPIPKIASPSIPQYLRSNTRHHLSSSVP----IEAETFSSFRPDMNMTMNMNLHNASTSSFNNEAFWK--------PLDSAIDHHSGDTNPNSNMNTTPNGNLSLDWLNLNL--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42944-1", "uniprot_id": "GZF3_YEAST", "id": "P42944-1", "name": "Protein GZF3", "aln": "MASQATTLRGYNIRKRDNVFEPKSSEN-------LNSLNQSEEEGHIGRWPPLGYEAVSAEQKSAVQLRESQAGASISNNMNFKANDKSFSTSTAGRMSPDTNSLHHILPKNQVKNNGQTMDANCNNNVSNDANVPVCKNCLTSTTPLWRRDEHGAMLCNACGLFLKLHGKPRPISLKTDVIKSRNRKSNTNHAHNLDNFRNQTLIAELKGDCNIESSGRKANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESKERSDSHLSATKLEVLMSGDCSRPNLKPKLPKQDTAIYQEKLLTFPSYTDVKEYSNSAHQSAFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNPSEVPNQIRSTMSSPDIISAKRNDPAPLSFHMASINDMLETRDRAISNVKTETTPPHFIPFLQSSKAPCISKANSQSISNSVSSSDVSGRKFENHPAKDLGDQLSTKLHKEEEIIKLKTR-INELELVTDLYRRHINELDGKCRALEERLQRTVKQEGNKGG-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . . * . . . . : . :. . . . :: : : . . * : . * .: . . . . : . * . :: . . .. : . . : .. . : : : . : : : . ", "identical_positions": 4, "similar_positions": 56, "identity": "0.71%" }, { "cls_id": "homologset.agr.FB:FBgn0001139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIT3-1", "uniprot_id": "TLE3_RAT", "id": "Q9JIT3-1", "name": "Transducin-like enhancer protein 3", "aln": "-------MYPQ-GRHPAPHQPGQ---------------------PGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQ----------QQLQAQHLSHATHGPPVQ-LPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAV--KDEKNHHE-------LDHRE-RESSTNNSVSPSESLR-------ASEKHRG-----SADYSMEAKKRKAEEKDSLS-RYDSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAP--TSPAS-VASSSSTPS-SKTKDLGHNDKSS-TPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPI----ASALRTPISLTS-SYAAPFAMMSHHEMNGSLTSP-SAYAGLHNIPSQMSA------AAAAAAAAYGRSPMV-----GFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPG-IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDIS--QPGSKSPISQLDCL---NRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08122-3", "uniprot_id": "TLE3_MOUSE", "id": "Q08122-3", "name": "Transducin-like enhancer protein 3", "aln": "-------MYPQ-GRHPAPHQPGQ---------------------PGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQ----------QQLQAQHLSHATHGPPVQ-LPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLAV--KDEKNHHE-------LDHRE-RESSTNNSVSPSESLR-------ASEKHRG-----SADYSMEAKKRKAEEKDSLS-RYDSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARGLKKDAP--TSPAS-VASSSSTPS-SKTKDLGHNDKSS-TPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIM-ASALRTPITLTS-SYPAPFAMMSHHEMNGSLTSP-SAYAGLHNIPSQMSA------AAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPG-IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDIS--QPGSKSPISQLDCL---NRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04726-1", "uniprot_id": "TLE3_HUMAN", "id": "Q04726-1", "name": "Transducin-like enhancer protein 3", "aln": "-------MYPQ-GRHPAPHQPGQ---------------------PGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQ----------QQLQAQHLSHATHGPPVQ-LPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV--KDEKNHHE-------LDHRE-RESSANNSVSPSESLR-------ASEKHRG-----SADYSMEAKKRKAEEKDSLS-RYDSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAP--TSPAS-VASSSSTPS-SKTKDLGHNDKSS-TPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIM-ASALRTPISITS-SYAAPFAMMSHHEMNGSLTSP-GAYAGLHNIPPQMSA------AAAAAAAAYGRSPMVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPG-IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDIS--QPGSKSPISQLDCL---NRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O13168-1", "uniprot_id": "TLE3B_DANRE", "id": "O13168-1", "name": "Transducin-like enhancer protein 3-B", "aln": "-------MYPQ-GRHPAPHQPGQ---------------------PGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNAILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLTQQQLQAQHLSHAAHGPPVQ-LPPHPSGLQPPGIPPVTGSGSGLLALGALGSQAHLPV--KDEKNHHD-------LEHRE-RESSTNNSVSPSDSLR-------ASEKHRG-----SSEYSLDPKKRRVEEKDNMS-RYDSDGDKSDD-LVVDVSNEDPATPRVSPSHSPPENGLDKARALKKDAP--NSPAS-VASSGSTPS-SKAKDHPHNDKSS-TPGLKSNTPTPRNDAPTPGTSNTPGLRPHPGKPPGMEALT---APALRTPLSIAP-PYGTPFMMGHHPEMNGSLTSP-GVYPGLH-ISPQMS---------AAAAAAYGRTHMP-----GFDPHPHMRAPVLPASLTSIPGGKPAYSFHVSADGQMQPVPFPPDALIGPG-IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDIS--QPGSKSPVSQLDCL---NRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O13166-1", "uniprot_id": "TLE3A_DANRE", "id": "O13166-1", "name": "Transducin-like enhancer protein 3-A", "aln": "-------MYPQ-GRHPAPQTPGQ---------------------PGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYIKLANEKTEMQRHYIM-----------------------YYEMSYGLNIEMHKQTEIAKRLNAILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGVRGLPNLPLT-QQLQAQHLSHT-HGPVAL-TPPHPSGLQPPGIPPVTGSGSGLLALGALGSQPHLPA--KDEKNHHD-------LEHR----ESTNNSISPSDSLRT------TSEKHRG-----SSDYSLDSKKRKVEDKDSMS-RYDSDGDKSDD-LVVDVSNEDPATPRGSPAHSPPENGIDKPRPAKKDTP--RRPAS-VASSGSTPS-SKTKPPEHNDKSS-TPGLKSKAPTPRNDAPTPGTSTTPGLRPILGKPP-MEALA---APALRTPLTCP-----TPFAMMSHHEMNGSLTNP-GVYAGLH-ISPQMS---------AAAAAAYGRSPMA-----GFEP-PHMRAPGLPASLTSISGGKPAYSFHVSADGQMQPVPFPPDALIGPG-IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDIS--QPGSKSPVSQLDCL---NRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFASQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWSTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZCM7-1", "uniprot_id": "D3ZCM7_RAT", "id": "D3ZCM7-1", "name": "", "aln": "-------MFPQ-SRHPTPHQAAG---------------------QPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQ----------QQLQAQHLSHG-HGPPVP-LTPHPSGLQPPGIPPLGGSASLLALSSALSGQSHLAI--KDDKKHHD-------AERHRGERPGN-NSLLVPDSLR-------GTDKRRN-----GPEFSSDIKKRKVDDKD----NYDSDGDKSDDNLVVDVSNEDPSSPHASPTHSPRENGIDKNRLLKKDAS--GSPAS-TASSGSSSS-LKSKEVNLHEKAN-TPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAMEPLVNQAAAGLRTPLAVPG-PYPAPFGMVPHAGMNGELTSPGAAYAGLHSMSPQMSA---AAAAAAAAVVAYGRSPMV-----GFDPPPHMRVPSIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPG-IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDIS--HPGNKSPVSQLDCL---NRDNYIRSCKLLPDGCTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62440-1", "uniprot_id": "TLE1_MOUSE", "id": "Q62440-1", "name": "Transducin-like enhancer protein 1", "aln": "-------MFPQ-SRHPTPHQAAG---------------------QPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQ----------QQLQAQHLSHG-HGPPVP-LTPHPSGLQPPGIPPLGGSASLLALSSALSGQSHLAI--KDDKKHHD-------AERHRDRESGTSNSLLVPDSLR-------STDKRRN-----GPEFSSDIKKRKVDDKD----NYDSDGDKSDDNLVVDVSNEDPSSPHASPTHSPRENGIDKNRLLKKDAS--GSPAS-TASSGSSSS-LKSKEVSLHEKAN-TPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAMEPLVNQAAAGLRTPLAVPG-PYPAPFGMVPHAGMNGELTSPGAAYAGLHSMSPQMSA---AAAAAAAAVVAYGRSPMV-----GFDPPPHMRVPSIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPG-IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDIS--HPGNKSPVSQLDCL---NRDNYIRSCKLLPDGCTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04724-1", "uniprot_id": "TLE1_HUMAN", "id": "Q04724-1", "name": "Transducin-like enhancer protein 1", "aln": "-------MFPQ-SRHPTPHQAAG---------------------QPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQ----------QQLQAQHLSHG-HGPPVP-LTPHPSGLQPPGIPPLGGSAGLLALSSALSGQSHLAI--KDDKKHHD-------AEHHRDREPGTSNSLLVPDSLR-------GTDKRRN-----GPEFSNDIKKRKVDDKDSS--HYDSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDAS--SSPAS-TASSASSTS-LKSKEMSLHEKAS-TPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAGLRTPLAVPG-PYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMS-----AAAAAAAVVAYGRSPMV-----GFDPPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPG-IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDIS--HPGNKSPVSQLDCL---NRDNYIRSCKLLPDGCTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04727-1", "uniprot_id": "TLE4_HUMAN", "id": "Q04727-1", "name": "Transducin-like enhancer protein 4", "aln": "MIRDLSKMYPQ-TRHPAPHQPA----------------------QPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQ----------Q-LQAQHLSHG-HGLPVP-LTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPI--KDEKKHHD-------NDHQRDRDSIKSSSVSPSASFR-------GAEKHRN-----SADYSSESKKQKTEEKEIAA-RYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAP--ISPAS-IASSSSTPS-SKSKELSLNEKST-TPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLA----SSLRTPMAVPC-PYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMS----AAAAAAAAAAAYGRSPVV-----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPG-IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDIS--HPGNKSPVSQLDCL---NRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLS-LKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62441-1", "uniprot_id": "TLE4_MOUSE", "id": "Q62441-1", "name": "Transducin-like enhancer protein 4", "aln": "MIRDLSKMYPQ-TRHPAPHQPA----------------------QPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQ----------Q-LQAQHLSHG-HGLPVP-LTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPI--KDEKKHHD-------NDHQRDRDSIKSSSVSPSASFR-------GSEKHRN-----STDYSSESKKQKTEEKEIAA-RYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAP--ISPAS-VASSSSTPS-SKSKELSLNEKST-TPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLA----SSLRTPMAVPC-PYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMS----AAAAAAAAAAAYGRSPVV-----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPG-IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDIS--HPGNKSPVSQLDCL---NRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLS-LKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07141-1", "uniprot_id": "TLE4_RAT", "id": "Q07141-1", "name": "Transducin-like enhancer protein 4", "aln": "MIRDLSKMYRR-RAHPAPHQPA----------------------QPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQAEIVKRLNAICAQVIPCLSQEQQQ-----------------------------------LQAQHLLTW-TWSACA-SDTTPLGFSQPFHP-SGSSAGLLALSSALGGQSHLPI--KDEKKHHD-------NDHQRDRDSIKSSSVSPSASFR-------GSEKHRN-----STDYSSESKKQKTEEKEIAA-RYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAP--ISPAS-VASSSSTPS-SKSKELSLNEKST-TPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLA----SSLRTPMAVPC-PYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMS----AAAAAAAAAAAYGRSPVV-----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPG-IPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDIT--DPGNKSPVSQLDCL---NRDNYIRSCRLLPDGRTLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLS-LKFAHCGKWFVRPGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TBS6-1", "uniprot_id": "A0AB32TBS6_DANRE", "id": "A0AB32TBS6-1", "name": "", "aln": "-------MFPQ-NRPPAPLQPPPGSSASAAAAAAAAAAAASGSTQPLKLTYPETLDRIKEEFQFLQTQYHSLKLECEKLATEKTEIQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNVICAQLIPFLSQEHQQQVVQAMERAKQVTMGELNASIGVRGLPPLP-PTQQLQAQHLSQH-AAQGLP-MAPHPSGLPHPGLALGGGS-GLLALSGALG--AQLAS--KDERAHLEAVAAAAAAEHHRDWPRGRLPALPMIPIDREPGPSSLSNGDKGR-----SSDYLSNGKKRKADEKEFMT-DYGSDAEKSDDNLVVD---EDPSSPRSVQSYSSRENGLDKLPPSRKEPLPQASPTS-LASSSSAASPSRSKEPPPREKSS-TPGMKPGTPMSQ-ESSTPGPSVPPQFRPVPGKPG-VDPLA----LGLRNPLAVQG-AYPPGAFGLPPPGVNGELAGAAGYGAGLHLVSPQMNGSAAAAAAAAAAAAGYGRSPVVG----YESPHPHMRVPGLPGSLQSAATGKPAYSFHVSADGQMQPVPFPPDALLGPG-IPRHARQIHTLSHGEVVCAVTISTSTRHVYTGGKGCVKVWDIS--QPGSKSPMAQLDCL---NRDNYIRSCKLLPDGRTLIVGG-EASTLSIWDLATPTPRIKAELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVSKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGSSIFQSKESSSVLSCDISPDDQFIVTGSGDKKATVYEVIY------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K109-1", "uniprot_id": "A0A0G2K109_RAT", "id": "A0A0G2K109-1", "name": "", "aln": "-------MYPQ-GRHPTPLQSGQ----------------------PFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSCPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNNLLGQQN-------------QLQPLS-HAPPVP-LTPRPAGLVG------AGATGLLALSGALAAQAQLVAAVKEDRVGVDT------EGSRVDRAASRSSSPSPPESLAE--------EEH-------PSSRDSNGKQQRAEDKNMSG-PYDSEEDKSDYNLVVDE--DQPSEPP-SPATTPCG-KAPLCIPARRDLT--DSPAS-LASSLGSPLP-RSKDLALNDLSTGTPASGSCGPSP----PQDSSTPGPSSASHLCQ-LATQPAPPTDSIALRSPLTLSS-PFTSSFSLGSHSTLNGDLSMP-GSYVS-LHLSPQVS----------SSV-VYGCSPLQMAFE----SHPHLRGSSIS--LPSIPGAKPAYSFHVSADGQMQPVPFPSDALVGTG-IPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVG--QPGSKTPVAQLDCL---NRDNYIRSCKLLPDGQSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPSQDWLAVGMESSHVEVLHVRKPEKYQLRLHESCVLS-LKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVB2-1", "uniprot_id": "TLE2_MOUSE", "id": "Q9WVB2-1", "name": "Transducin-like enhancer protein 2", "aln": "-------MYPQ-GRHPTPLQSGQ----------------------PFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSYPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQN-------------QLQPLS-HAPPVP-LTPRPAGLVG------AGATGLLALSGALAAQAQLVAAVKEDRVGVDA------EGSRVDRAASRSSSPSPPESLVE--------EDH-------PSSRGGSGKQQRAEDKDLSG-PYDSEEDKSDYNLVVDE--DQPSEPP-SPVTTPCG-KAPLCIPARRDLT--DSPAS-LASSLGSPLP-RSKDIALNDLPTGTPASRSCGTSP----PQDSSTPGPSSASHLCQ-LAAQPAAPTDSIALRSPLTLSS-PFTSSFSLGSHSTLNGDLSMP-GSYVG-LHLSPQVS----------SSV-VYGRSPLQMAFE----SHPHLRGSSVS--LPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTG-IPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVG--QPGSKTPVAQLDCL---NRDNYIRSCKLLPDGQSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEKYQLRLHESCVLS-LKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04725-1", "uniprot_id": "TLE2_HUMAN", "id": "Q04725-1", "name": "Transducin-like enhancer protein 2", "aln": "-------MYPQ-GRHPTPLQSGQ----------------------PFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQ---------------QLQPLSHHAPPVP-LTPRPAGLVG------GSATGLLALSGALAAQAQLAAAVKEDRAGVEA------EGSRVERAPSRSASPSPPESLVE--------EER-------PSGPGGGGKQ-RADEKEPSG-PYESDEDKSDYNLVVDE--DQPSEPP-SPATTPCG-KVPICIPARRDLV--DSPAS-LASSLGSPLP-RAKELILNDLPASTPASKSCDSSP----PQDASTPGPSSASHLCQ-LAAKPAPSTDSVALRSPLTLSS-PFTTSFSLGSHSTLNGDLSVP-SSYVS-LHLSPQVS----------SSV-VYGRSP-VMAFE----SHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAG-IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVG--QPGAKTPVAQLDCL---NRDNYIRSCKLLPDGRSLIVGG-EASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLS-LKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58II93-1", "uniprot_id": "A0AC58II93_DANRE", "id": "A0AC58II93-1", "name": "", "aln": "-------MYPQ-GRHPVPLQPGQ----------------------SFKFTVLETLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYIM-----------------------YYEMSYGLNIEMHKQAEIVKRLSAICAQIIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQ--------------QLQHLSHHTPGIP-LTPHPSGLSL------GGTSSLLALTGALGVTAHLAN--KDERNHLDP------EHLREG-APSRSKSVSSTDSQAV--------EDRQGPSGVYSSQAGGDAKRRRCEEKDILQSHYDSDGDKSEDNLVVDVSNEEASSPVGSAPLSPHGNGLDRALPLRKELP--GSPSPPTASPPHSPTPGKNKDTAQTEKSQ-SPSSKSGNSSPSHHDPLTPGPPGPPGPSTSCLRLVNKPASSADPLALRSPLTMTPGSYPAHFGVVSHAGLNGELASP-GGFGGSLTLSPQIS----------AAASAYTRSP-MVAYE----SRSHLRPSGLSSSLPGSTSGKPAYSFHVSADGQMQPVPFPPDALLGPG-IPRHARQIHTLSHGEVVCAVTISTSTRHVYTGGKGCVKVWDIS--QPGSKSPMAQLDCL---NRDNYIRSCKILPDGRTLIVGG-EASTLSIWDLATPTPRIKAELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVSKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDVSPDDKYIVTGSGDKKATVYETEKQLANLKDPITEP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16371-1", "uniprot_id": "GROU_DROME", "id": "P16371-1", "name": "Protein groucho", "aln": "-------MYPSPVRHPAAGGPPP--------------------QGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVM-----------------------YYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGHQ---------QQHGIQQLLQQIHAQQVPGGPPQPMGALNP----FGALGATMGLPHGPQGLLNKPP--EHHRPDIKPTG----LEGPAAAEERLRNSVSPADREK---------YRTRS-----PLDIENDSKRRKDEKLQ------EDEGEKSDQDLVVDVANEMES-------HSPRPNGEHVSMEVRDRES-----LN--GERLEKPS---SSGIKQERPPS-RSGSSSSRSTPSLKTKDMEKPGTPGAKARTPTPNAAAPAP-----GVNPKQMMPQGPPPAGYPGAPYQRPADPYQRP-------------------------PSDPAYGRPPPMP-----YDPHAHVRTNGIP-HPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVG-IPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDIS--QPGNKNPVSQLDCL---QRDNYIRSVKLLPDGRTLIVGG-EASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLS-LRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVYEVIY------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6AID4-1", "uniprot_id": "A0A8I6AID4_RAT", "id": "A0A8I6AID4-1", "name": "", "aln": "------------------------------------------------------------------------------MSEEKEDS-FRTLR---------------------------IYDETEEIQKMPESSG--------IFPHHGQQEQHQMDS--------AQGMLQLPPCPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQRGPVCQEMHSMTQQQWDPQ--------------AQDASGLQPMWFSEAEP-EGGASS-SFQLGDATGQFSSSSLPN---------------------------------------------------------------------------------------------------------------------REVWSFLKAIP------PIPDEAVVKRK-CPRGSWRVGTLRHGKRVNAIAISSAPRHVYTCGTGYIRVWDEDALHASDRAPQAQLDFQ---DPRNRVLACKLFPDEQSLITGG-MARALTLWDLAP-TPQIRAQMASTGPICYSLALSSDAHICLASFK-GFVEIWDVQNQILIRKHEVPPYGSRCVDIT--GFKFWTGGEDTTLYSWDLRSYQKLQQHNLCHEILSITHDPSEEWVLAGLKMSDIVILHAHREEKYKAVVQRYTQHHNLKFASCGTYFMAT-LDEMIHCLAAPSLRRLFQAEECYDILCCDVSSDNRYLVTGSKES-ATVYQLLY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1W2P7S4-1", "uniprot_id": "A0A1W2P7S4_MOUSE", "id": "A0A1W2P7S4-1", "name": "", "aln": "------------------------------------------------------------------------------MSEEKEDL-FRTLR---------------------------IYDETKEIKKMPESSG--------VFSHHGQREQHQVDG--------AQGMLQLPPCPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQHDPVCQEMHSMMQQQWDPH--------------AQDTSGLQSMWFSEAEP-EGGTGS-RFQPGDKTGQFSSPSLPN---------------------------------------------------------------------------------------------------------------------REVWSFLKAIP------PIPDEAVVKQK-SPCGSWRVGTLRHGKRVNAIAISSAPCHVYTCGTGYIRVWDENALHASDRAPQAQLDFQ---DPRNRVLTCKLFPDEQSLITGG-MARGLTLWDLAP-TPQVRAQMASTGSICYSLALSSDAHLCLASFK-GFVEIWDVQNQILIRKHEVPPYASRCVDIT--GFKFWTGGEDTTLYSWDLRSYQKLQQHSLCHEILSITHDPSEEWVLAGLKMSDVVILHAHREEKYKAIVQRYTQHHNLKFASCGTYFMAT-LDEVIHCLAAPSLRRLFQAEECYNILCCEVSSDNRYLVTGSKDS-ATVYQLLY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2PR48-1", "uniprot_id": "TLE7_HUMAN", "id": "A0A1W2PR48-1", "name": "Transducin-like enhancer protein 7", "aln": "------------------------------------------------------------------------------MSGEKEEASLRMFG---------------------------AYGEPEERRDVLESSG--------VSSQPEPQVQQQLGS--------LLGVPWQPPGPP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQHSPADQETSTVTQQQWHLQ--------------GLGRSELQAAGLPDAQPGEAAESSPSFLLGSEVGQPYSSSSPS---------------------------------------------------------------------------------------------------------------------EEVLSLLRAIP------PIPDEVVVRQKRAPQGSWKVGTLFHGKRVYAVAISGSTHHVYTCGSGYIRVWDESALHAGEKAPRAQLDLQ---HPQDRVVTCKLFPDERSLITGG-ASQAVTLWDLAP-TPQVRAQLTSTGPTCYSLAVSSDAHICLACFH-GFVEIWDLQNQILIRKHEVPVYGSRCVDIT--GNIFWTGGEDTILYSWDLRSYQRLHQHNLQNEILSITHDPGEEWVLAGLRTSDIVFLHTRRNEQFKALMKKYTRHHSLKFASCGSYFVTA-IDTRLSGLEAPSLQKLFQIEESSGILCCDVSSDNQYLVMGSSSS-ATIYQLLY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LXS4-1", "uniprot_id": "F1LXS4_RAT", "id": "F1LXS4-1", "name": "", "aln": "---------------------------------------------SPREGCGPSQNRLERGTLHSQSNDTFG--GILLKGTEASNSSGRFLS----------------------IMEQLPEELKIILSEMTAKLNNISSLVEN-FQATGVLSRTP---------------------HIS---------------------------------------------------------------------------------------------KMVKTTQNSAK-----------------------KEDKPVPEPADPQNPEFKAIPGPQLSTRRRFLSEVDEPQDPQPVWDKEPHFWQGSLTQEIWKFFM-----------DSRQENQ--HGGKVFSQESKDSGLRYSKPEPQPRHRNSLSDSDDPILIKSPSDLLSDYQED------------------------------------------------------------------------------------ISEPQFETQESSGRAHEFLNPLFWDSEV-------PGTSLWQSERFTVPQALQKVRVLKHQELLLAIAVSSFTRHVFTCSQSGIKVWNLMSQVAEDRHPESHLQCDGVQPNRGYLRTCLLSSNSRTLFAGGYNLPGVFVWDLAARSLYEKYQLPCDGLSCQAL-ASTKENMVFAGFTDGTVRIWDLRTQEIVRDLNSPAGAAKCLVIK--DDSVWMGGLDACLRCWDLRVAKMSLEYPVQSQVH-------------------------RK----------------------GQWWVSVGMDNLITVHSMPMGAKLFQVPEAAAVRCFDITENSRLIVTGSGDC-ASIYHIKY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVB3-1", "uniprot_id": "TLE6_MOUSE", "id": "Q9WVB3-1", "name": "Transducin-like enhancer protein 6", "aln": "------------------------------------------------------------MTSHRQSSDTFG--GILP-----STLSSRYLS----------------------IVNQLPEEFSSVVSEMMVHLENIFSLAENFFQAIERFSRTPDLLERNKMSIGVGAEGDSWPCHVSH----------------------------------------------------------------------------------------EAPMGSAQTTENSAK-----------------------EEDKQVPESAALQHPKFKSTPGPQLPTRRRFLSESDELQDPQPVWDAEPQFCQGFLIQGLWELFM-----------DSRQKNQQEHGGEDSSQESKDSGLCDFKPEPQPRHRNSLSDSADPFLIKSPSALLDYYQED------------------------------------------------------------------------------------VSRPQPETQESSGRADKFLKPLSWGSEVLESSCNQPSTALWQLERFTVPQALQKVRVLKHQELLLVVAVSSFTRHVFTCSQSGIKVWNLVNQVAEDRDPESHLKCS-VQDNKVYLRTCLLSSNSRTLFAGGYNLPGVIVWDLAAPSLYEKCQLPCEGLSCQAL-ANTKENMALAGFTDGTVRIWDLRTQEIVRNLKGPTNSARNLVVK--DDNIWTGGLDACLRCWDLRMAKVSLEHLFQSQIMSLAHSPTEDWLLLGLANGQHCLFNSRKRDQVLTVDTKDNTILGLKFSPNGKWWASVGMGNFITVHSMPTGAKLFQVPEVGPVRCFDMTENGRLIITGSRDC-ASVYHIKY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H808-1", "uniprot_id": "TLE6_HUMAN", "id": "Q9H808-1", "name": "Transducin-like enhancer protein 6", "aln": "----------------------------------------MTSRDQPRPKGPPKSTSPCPGISNSESSPTLNYQGILNRLKQFPRFSPHFAA----------------------ELESIYYSLHKIQQDVAEHHKQIG----NVLQIVESCSQLQG--------------------FQS---------------------------------------------------------------------------------------------EEVSPAEPASP-----------------------GTPQQVKDKT-LQESSFEDIMATRSSDWLRRPLGEDNQPETQLFWDKEPWFWHDTLTEQLWRIFAG--------VHDEKAKPRDRQQAPGLGQESKAPGSCDPGTDPCP------EDASTPRPPEASSSPPEGSQDR------------------------------------------------------------------------------------NTSWG-VVQEPPGRASRFLQSISWDPEDFEDAWKRPDALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAEDRFPESHLPIQ---TPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLNCQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGPDACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQ-WLQSTSGSQRHMVGQKDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVTGSGEH-ASVYQITY------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . * * . * :: * * : : . ::* . :*:* . :::*. . : * ::* : : : .: :*:.** : :****. : : ::.. . * :* . . :: :: * : :**:: : ::*. : . : :. . .* ** * : .** * :: . :: * :: . : * :*: * : . ::: :.: :: ** . *::*. ", "identical_positions": 39, "similar_positions": 91, "identity": "4.37%" }, { "cls_id": "homologset.agr.FB:FBgn0001142", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09606-1", "uniprot_id": "GLNA_RAT", "id": "P09606-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MATS----ASSHLNKGIKQMYMNLPQ-GEKIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRDPN-KLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRT-CLLNETGDEPFQYKN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15105-1", "uniprot_id": "GLNA_MOUSE", "id": "P15105-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MATS----ASSHLNKGIKQMYMSLPQ-GEKVQAMYIWVDGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRKDPN-KLVLCEVFKYNRKPAETNLRHICKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPYAVTEAIVRT-CLLNETGDEPFQYKN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15104-1", "uniprot_id": "GLNA_HUMAN", "id": "P15104-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MTTS----ASSHLNKGIKQVYMSLPQ-GEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPN-KLVLCEVFKYNRRPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRT-CLLNETGDEPFQYKN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B814-1", "uniprot_id": "A0A8M2B814_DANRE", "id": "A0A8M2B814-1", "name": "Glutamine synthetase", "aln": "------------------MFILDGLRAG--SFGLHMEWSQFYITDSSLNKALRQQYLSLPQ-GPFCQVTYIWIDGSGEGLRNKTRTMESEPKSVADLPEWTFDGSSTGQSEGHNSDMLLIPVRMFRDPFLLDPN-KLVLCEVLKHTREPAESNHRNKCNKVMEKVKGLQPWFGMEQEYTLLGVDGHPYGWPRLGFPKPQGLYYCSVGADRAFGRDIVDCHYKACLYAGIKITGTNAEVMPSQWEYQVGPCEGIEVADHLWMSRFVLHRVCEDFGVVATLDPKPMVGDWNGAGCHINVSTASMREEEGIEHIEKAIEKLSRRHEEHIRVYDPHGGEDNKRRLTGRHETSSIHDFSAGVANRGASIRIPRQVGQEKCGYFEDRRPAANCDPYAVTCEMAVT-CMLDDVHE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20477-1", "uniprot_id": "GLNA1_DROME", "id": "P20477-1", "name": "Glutamine synthetase 1, mitochondrial", "aln": "MALRVAGLFLKKELVAPATQQLRLLRTGNTTRSQFLANS----PNTALDKSILQRYRNLETPANRVQATYLWIDGTGENIRLKDRVLDKVPSSVEDLPDWQYDGSSTYQAHGENSDTTLKPRAIYRDPFKPGKNDVIVLCDTYSADGKPTASNKRAAFQAAIDLISDQEPWFGIEQEYTLLDVDGRPFGWPENGFPAPQGPYYCGVGADRVYARDLVEAHVVACLYAGIDFAGTNAEVMPAQWEFQIGP-AGIKACDDLWVSRYILQRIAEEYGVVVTFDPKPMEGQWNGAGAHTNFSTKEMRADGGIKAIEEAIEKLSKRHERHIKAYDPKEGKDNERRLVGRLETSSIDKFSWGVANRAVSVRVPRGVATAGKGYLEDRRPSSNCDPYAVCNAIVRT-CLLNE-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32288-1", "uniprot_id": "GLNA_YEAST", "id": "P32288-1", "name": "Glutamine synthetase", "aln": "-----------------------------------MAEA------SIEKTQILQKYLELDQ-RGRIIAEYVWIDGTG-NLRSKGRTLKKRITSIDQLPEWNFDGSSTNQAPGHDSDIYLKPVAYYPDPFRRGDN-IVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQPGGMKYIEQAIEKLSKRHAEHIKLY----GSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPRSVAKEGYGYFEDRRPASNIDPYLVTGIMCETVCGAIDNADMTKEFERESS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. : * * .* *:*:**:* .:* * *.:. ..: :**:* :***** *: * :** * * : *** . * :*:. . * * * : .. . ***:******:. . :*** *:* *** ***.***.:.:.**:::.* ******:.::* ******:***:*:** ** *.**::*:.*:*:.*::*: ::.***: *:*****.* *.** ** *:. **:**:***:** **: * * ** **.* **:.: ** *****. *:*:** *. **:*****::* **: * : * * : ", "identical_positions": 149, "similar_positions": 94, "identity": "35.65%" }, { "cls_id": "homologset.agr.FB:FBgn0001145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09606-1", "uniprot_id": "GLNA_RAT", "id": "P09606-1", "name": "Glutamine synthetase", "aln": "---------------MATS----ASSHLNKGIKQMYMNLPQGE-KIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRDPNKLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCL--LNETGDEPFQYKN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15105-1", "uniprot_id": "GLNA_MOUSE", "id": "P15105-1", "name": "Glutamine synthetase", "aln": "---------------MATS----ASSHLNKGIKQMYMSLPQGE-KVQAMYIWVDGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRKDPNKLVLCEVFKYNRKPAETNLRHICKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCL--LNETGDEPFQYKN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15104-1", "uniprot_id": "GLNA_HUMAN", "id": "P15104-1", "name": "Glutamine synthetase", "aln": "---------------MTTS----ASSHLNKGIKQVYMSLPQGE-KVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL--LNETGDEPFQYKN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B814-1", "uniprot_id": "A0A8M2B814_DANRE", "id": "A0A8M2B814-1", "name": "Glutamine synthetase", "aln": "MFILDGLRAGSFGLHMEWSQFYITDSSLNKALRQQYLSLPQGP-FCQVTYIWIDGSGEGLRNKTRTMESEPKSVADLPEWTFDGSSTGQSEGHNSDMLLIPVRMFRDPFLLDPNKLVLCEVLKHTREPAESNHRNKCNKVMEKVKGLQPWFGMEQEYTLLGVDGHPYGWPRLGFPKPQGLYYCSVGADRAFGRDIVDCHYKACLYAGIKITGTNAEVMPSQWEYQVGPCEGIEVADHLWMSRFVLHRVCEDFGVVATLDPKPMVGDWNGAGCHINVSTASMREEEGIEHIEKAIEKLSRRHEEHIRVYDPHGGEDNKRRLTGRHETSSIHDFSAGVANRGASIRIPRQVGQEKCGYFEDRRPAANCDPYAVTCEMAVTCM--LDDVHE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20478-1", "uniprot_id": "GLNA2_DROME", "id": "P20478-1", "name": "Glutamine synthetase 2, cytoplasmic", "aln": "----------MSARILEDS----PNARINKTILDRYLSLPLQENIVQATYVWIDGTGEDLRCKDRTLDFIPQSPKELPVWNYDGSSCYQAEGSNSDTYLYPVAIYKDPFRRGNNILVMCDTYKFDGTPTDTNKRKTCLEVANKCAAEEPWFGIEQEYTFLDFDGHPLGWPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIKVSGTNAEVMPAQWEFQVGPCEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNGAGAHTNVSTKAMREDGGIRDIEKAVAKLSKCHERHIRAYDPKQGQDNARRLTGKHETSSINDFSAGVANRGCSIRIPRGVNDDGKGYFEDRRPSSNCDPYSVVEAILRTIC--LDE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32288-1", "uniprot_id": "GLNA_YEAST", "id": "P32288-1", "name": "Glutamine synthetase", "aln": "---------------MAEA------SIEKTQILQKYLELDQRG-RIIAEYVWIDGTG-NLRSKGRTLKKRITSIDQLPEWNFDGSSTNQAPGHDSDIYLKPVAYYPDPFRRGDNIVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQPGGMKYIEQAIEKLSKRHAEHIKLY----GSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPRSVAKEGYGYFEDRRPASNIDPYLVTGIMCETVCGAIDNADMTKEFERESS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. : : *:.* *:*:**:* .** * **:. . :** *.:**** *: * :** * *. : *** . * :*:. : * . * *: . .: . ***:*****::. .. *** *:* *** ***.***.:.:.**:::.**:******::::* ******:***:*:*** ** :.*.**::*:.***:.*:**: ::.***: *:*****.* *.** **: *:. **:*: ***: * **: * * ** **** ***:.: **:*****..****** * .: ********::* **: *. : * ::: ", "identical_positions": 154, "similar_positions": 100, "identity": "38.79%" }, { "cls_id": "homologset.agr.FB:FBgn0001147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRA8-1", "uniprot_id": "D3ZRA8_RAT", "id": "D3ZRA8-1", "name": "", "aln": "--------------MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPD-VEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSG---LVSSISRVLRIKFGK-KEDDEEGDKKE-EDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGAN--QLAAFN---------HLLPGGFPPTGMPTLPPYQLPDSAYPTTTVSQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADSSSAYGARHSFSSYSDSFMNPGAPSNHMNP-VSNGLSPQVMSILSNPSAVPPQPQADFSISP-LHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPV-AGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47239-1", "uniprot_id": "PAX7_MOUSE", "id": "P47239-1", "name": "Paired box protein Pax-7", "aln": "--------------MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPD-VEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPS-----VSSISRVLRIKFGK-KEDDEEGDKKE-EDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGAN--QLAAFN---------HLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPGAPSNHMNP-VSNGLSPQVMSILSNPSAVPPQPQADFSISP-LHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPV-AGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23759-3", "uniprot_id": "PAX7_HUMAN", "id": "P23759-3", "name": "Paired box protein Pax-7", "aln": "--------------MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPD-VEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSG---LVSSISRVLRIKFGK-KEEEDEADKKE-DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGAN--QLAAFN---------HLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP-LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPV-AGYQYGQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57418-1", "uniprot_id": "O57418_DANRE", "id": "O57418-1", "name": "", "aln": "--------------MATLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPD-VEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVLRARFGK-KDDDDECDKKD-EDGEKKTKHSIDGILGDKGN--RTDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGAN--QLAAFN---------HLLPGGFPPTGMPTLPTYQLPESTYPSTTLSQ---DGSSTLHRPQPLPPSSMHQGGLSADSGSAYGLSSN--RHTFSSYSETFMSPTASSNHMNP-VSNGLSPQVMSILSNPSAVPSQPQHDFSISP-LHGGLEASNPISASCSQRSDPIKSVDSLASTQSYCPPTYSATSYSVDPVTAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGDHSAVLGLLQVETGQAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IKH0-1", "uniprot_id": "A0AC58IKH0_DANRE", "id": "A0AC58IKH0-1", "name": "", "aln": "MRLSGMITQNQYLRMSSLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPD-VEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRSTVPSGEASSVSSISRVLRARFGK-KDDEDDCDKKD-DTGEKKTKHSIDGILGDKG---RMDEVSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGAN--QLAAFN---------HLLPGGFPPTGMPTLPTYQLPESSYPTTTLPQ---DVSGTVHRPQPLPPSTMHQGGLSSDSSSAYGLSSN--RHSFSSYTDTFMSQSASSNHMNP-VSNGLSPQVMSILSNPSAVAPQPQHEFSISP-LHSSLEASNPISASCSQRSEPIKTADSLPSSQSYCPPTYSTTSYSVDPVTAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLQVETGQAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6ATQ4-1", "uniprot_id": "A0A8I6ATQ4_RAT", "id": "A0A8I6ATQ4-1", "name": "", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPD-VEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGAN--QLMAFN---------HLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP-LTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTTGYSMDPV-TGYQYGQYGQ------SKPWTF--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24610-1", "uniprot_id": "PAX3_MOUSE", "id": "P24610-1", "name": "Paired box protein Pax-3", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPD-VEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGAN--QLMAFN---------HLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP-LTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTAGYSMDPV-TGYQYGQYGQ------SKPWTF--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23760-1", "uniprot_id": "PAX3_HUMAN", "id": "P23760-1", "name": "Paired box protein Pax-3", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVN-QLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPD-VEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGAN--QLMAFN---------HLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP-LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPV-TGYQYGQYGQ------SKPWTF--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09083-1", "uniprot_id": "GSBN_DROME", "id": "P09083-1", "name": "Protein gooseberry-neuro", "aln": "-----------------MDMSSANSLRP------LFAGYPFQ-----GQGRVN-QLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPK-VTSPE-IETRIDELRKENPSIFSWEIREKLIKEGFADP---PS-----TSSISRLLRG-----SDRGSEDGRKD---------YTINGILGGRDS-----DISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHSGGSNSGLSPMNSGSSNVGVGVGLSGATAPLGYGPLGVGSMAGYSPAPGTTATG-AGMNDGVHHAAHAPSS--HHSAATAAAAAHHHTQMGGYDLVQSAAQHGFPGGFAQPGHFGS---QNYYHQDYSKLTIDDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWSQAAYHAAANYNAHVAQHQLNDYAAAAAHGNPA-SAYSHPLPTQG----QAKYWS---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04116-1", "uniprot_id": "YHP1_YEAST", "id": "Q04116-1", "name": "Homeobox protein YHP1", "aln": "------------------MESRNTVLPSLPNIITGTSNSPFQLHTLPNTNFPSDDQGDIRLPPLAASAHIVRPVVNIYKS---PCDEERPKRKSPQAVDFLSQRVTTS--MTP----LSKPKKLSSHSPFTPTVRVCSKEQPPQSMHSYKKVNILTPLSAAKAVLT------PTTRKEKKRSFAFITHSQETFPKKE----------------------------------PKIDNARLARRKRRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGN---------------------------------------------------TSHCKVHSNDSMSMISYSDAALEITSTP-------------TSTKEAITAELLKTSPANT----------SSIFEDHHITPCKPGGQLKFHR--KSVLVKRTLSNTGHSEIIKSPKGKENRLKFNAYERKPLGEVDLNSFKN-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :. *:: . . . : *.: : . . ** :*:: ** .* * * .*. : * : : * ***: ::: . . : :*:* . :. : . : .: : : . :*: * : * **.* :: :* *: **.. *: .* **:: ::* :*:**.*:* :*: ... :* . .. . . :: . : .. .. . : . : . .. . : : . . ", "identical_positions": 40, "similar_positions": 96, "identity": "7.34%" }, { "cls_id": "homologset.agr.FB:FBgn0001148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATQ4-1", "uniprot_id": "A0A8I6ATQ4_RAT", "id": "A0A8I6ATQ4-1", "name": "", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTTGYSMDPV-TGYQYGQYGQ------SKPWTF--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24610-1", "uniprot_id": "PAX3_MOUSE", "id": "P24610-1", "name": "Paired box protein Pax-3", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTAGYSMDPV-TGYQYGQYGQ------SKPWTF--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23760-1", "uniprot_id": "PAX3_HUMAN", "id": "P23760-1", "name": "Paired box protein Pax-3", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPV-TGYQYGQYGQ------SKPWTF--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57418-1", "uniprot_id": "O57418_DANRE", "id": "O57418-1", "name": "", "aln": "--------------MATLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVLRARFGK-KDDDDECDKKD-EDGEKKTKHSIDGILGDKGN--RTDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPTYQLPESTYPSTTLSQ---DGSSTLHRPQPLPPSSMHQGGLSADSGSAYGLSSN--RHTFSSYSETFMSPTASSNHMNP-VSNGLSPQVMSILSNPSAVPSQPQHDFSISPLHGGLEASNPISASCSQRSDPIKSVDSLASTQSYCPPTYSATSYSVDPVTAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGDHSAVLGLLQVETGQAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IKH0-1", "uniprot_id": "A0AC58IKH0_DANRE", "id": "A0AC58IKH0-1", "name": "", "aln": "MRLSGMITQNQYLRMSSLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRSTVPSGEASSVSSISRVLRARFGK-KDDEDDCDKKD-DTGEKKTKHSIDGILGDKG---RMDEVSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPTYQLPESSYPTTTLPQ---DVSGTVHRPQPLPPSTMHQGGLSSDSSSAYGLSSN--RHSFSSYTDTFMSQSASSNHMNP-VSNGLSPQVMSILSNPSAVAPQPQHEFSISPLHSSLEASNPISASCSQRSEPIKTADSLPSSQSYCPPTYSTTSYSVDPVTAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLQVETGQAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23759-3", "uniprot_id": "PAX7_HUMAN", "id": "P23759-3", "name": "Paired box protein Pax-7", "aln": "--------------MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSG---LVSSISRVLRIKFGK-KEEEDEADKKE-DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPV-AGYQYGQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRA8-1", "uniprot_id": "D3ZRA8_RAT", "id": "D3ZRA8-1", "name": "", "aln": "--------------MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSG---LVSSISRVLRIKFGK-KEDDEEGDKKE-EDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSAYPTTTVSQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADSSSAYGARHSFSSYSDSFMNPGAPSNHMNP-VSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPV-AGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09082-1", "uniprot_id": "GSB_DROME", "id": "P09082-1", "name": "Protein gooseberry", "aln": "------------------MAVSALNMTPYFG------GYPFQ-----GQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRPGVIGGSKPR-VATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPS-----VSSISRLLRGSSGS------------------GTSHSIDGILGGGAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLNTQQVPSF------------APTSTSFGATPTTSAAPAPNM-----GMSLYSSQSWPSSGAYEN-HAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQ----QPGTGSEFMTSTYGVGSSNATYPS-AAYSMPQTPATSAEQLRSQFASAAASGSHHPSTWDSYNFAGSFFPPASAAGNH-----ISGYHH-QVDQ-------KSSMMTTAP------TYPYFGF---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * * * *:*:: ***********************::***** *:******************** *:*********.******: *:***:*.:*** *:.:**:****** :*:: . **: ..** ******:** *. :.*******. . :: *: ::**.: ************: :*:: **: * **:***:******** : **************** *** .::*: :* ** ..: . :: ..: . ::: .*. *.* ::. .: : . ** :.: : . :* .. : ... .: . . . . . . :* .. : . .:::.:. . . ** : .: **: :: .: :**:: * .* * : ", "identical_positions": 179, "similar_positions": 123, "identity": "33.71%" }, { "cls_id": "homologset.agr.FB:FBgn0001149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P20432-1", "uniprot_id": "GSTD1_DROME", "id": "P20432-1", "name": "Glutathione S-transferase D1", "aln": "-----------------------------------------------------------------------------------------------------MVDFY----------YLPGSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDN---GFALWESRAIQVYLVEKYGKTDS---LYPKCPKKRAVINQRLYFDMG---TLYQSFANYYYPQVFAKAPADPEAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVST-------FEVAKFEISKYANVN-----RWYENAKKVTPGWEENWAGCLEFKKYFE------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..*: : *:* .* :. . :*.. *. :*::: *** ***:.:**: :*:*:*: .:::*** ** ::**:** * . *:.. .:: ** *:*: . .: . :: * : *.* . .::. .: .:: * : * .* . : * :: :* *: . : :.. .: * : ..:: . : ::. ::.*:: ", "identical_positions": 44, "similar_positions": 90, "identity": "12.43%" }, { "cls_id": "homologset.agr.FB:FBgn0001168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14469-1", "uniprot_id": "HES1_HUMAN", "id": "Q14469-1", "name": "Transcription factor HES-1", "aln": "MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMT-----------------------------------------------------------QINAMTYPGQPHPALQAPPPPPP-----GPGGPQHAPFAPPPP-LVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTAD-SMWRPWRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35428-1", "uniprot_id": "HES1_MOUSE", "id": "P35428-1", "name": "Transcription factor HES-1", "aln": "MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMT-----------------------------------------------------------QINAMTYPGQAHPALQAPPPPPPS----GPAGPQHAPFAPPPPPLVPIPGGAAPPPGSAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGSSLTSD-SMWRPWRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCC6-1", "uniprot_id": "HES4_HUMAN", "id": "Q9HCC6-1", "name": "Transcription factor HES-4", "aln": "MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLR-----------------------------------------------------------QLGPSRRP---------------------------ASLSPAAP-------AEAPAP---------------EVYAGRPLLPSLGGPFPLLAP--------PLLPGLTR--ALPAAPRAGPQGPG-------GPWRPWLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14003-1", "uniprot_id": "HAIR_DROME", "id": "P14003-1", "name": "Protein hairy", "aln": "MVTGVTAANMTNVLGTAVVPAQLKETPLK---SDRRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQQAADPKIVNKFKAGFADCVNEVSRFP----GIEPAQRRRLLQHLSNCINGVKTELHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03062-1", "uniprot_id": "HES5_RAT", "id": "Q03062-1", "name": "Transcription factor HES-5", "aln": "-------------MAPSTVAVEMLSPKEK-----NRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQP-NSKLEKADILEMAVSYLKHS---KAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLT--LHAASDTQMKLLYHFQ--------------------------------------------------------------------------------------------------RPPAPAAP---------------------------------VKETPTPG--------------AAPQPARSSTKAAASVSTSRQS---------ACGLWRPW--", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .... : .: **::** ** ***..: :** *: : :. . :********** :* :*: : : : .: *: *: *. :* . : :** *: : ... * . * : . . **** ", "identical_positions": 37, "similar_positions": 46, "identity": "10.69%" }, { "cls_id": "homologset.agr.FB:FBgn0001170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0JPN1-1", "uniprot_id": "HLX_RAT", "id": "A0JPN1-1", "name": "H2.0-like homeobox protein", "aln": "----MFAAGLAPFYASNFSLWSAAYCSSAGPGGCS---FALDPAAVKKPSFCIADILHAGVGEPGPAAEGLVGAS-AALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHQHLPQQPPTQQQQPQQQPPPPPRAGSLQPPTSGTRVVP--HHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPTGVHLAGLQPSAGQFFASLDP-ISEAS---------AILSPLSSNPRNSVQHQFQDTFPG--PYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAE-GEREERSPSRSEGEAESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSASG-------SSFSFSSSSSLGSSNGSAGSASSLG-SNCSELLPSHQPSVTSGPQSPEIAQVPLAGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61670-1", "uniprot_id": "HLX_MOUSE", "id": "Q61670-1", "name": "H2.0-like homeobox protein", "aln": "----MFAAGLAPFYASNFSLWSAAYCSSAGPGGCS---FALDPAAVKKPSFCIADILHAGVGEPGPAAEGLVGAS-AALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAFHQHLPQQSPTQQQQPQQQPPPPPRAVSLQPPTSGTRVVP--HHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLAGLQPSAGQFFASLDP-ISEAS---------AILSPLSSNPRNSVQHQFQDTFPG--PYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAE-GEREERSPSRSEGEAESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSTSG-------SSFSFSSTSSLGSGNTHVGSASSLG-GNCSELPSAHQPSVTSSPQSPEIAQAPLAGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14774-1", "uniprot_id": "HLX_HUMAN", "id": "Q14774-1", "name": "H2.0-like homeobox protein", "aln": "----MFAAGLAPFYASNFSLWSAAYCSSAGPGGCS---FPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDP-INEAS---------AILSPLNSNPRNSVQHQFQDTFPG--PYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AAR4-1", "uniprot_id": "A0AB13AAR4_DANRE", "id": "A0AB13AAR4-1", "name": "H2.0-like homeobox protein", "aln": "----MYTTGLNPFYASNFSLWT-AYCSAG---------FAVD--SMKKPSFCIADILHVG------DAENIQGSS--SLMAHIG---ARAQVHSSG-SPLRPSPVTP--------DARLHPAYLRHGIHLTSRAAIN-----------------------------------APPPTSKDLKFGIDRILSTDFEPKSKESPSLRDLTSIVSPNRQSAVHVS-----ASPYFASIDPTMSETS---------SLMGSIGNAARQSGQHQFQDTFPGR-PYAVLSKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKEKEQPDKS-----AAETEQKERDDS----ECETEPSESE-FEDGPEDKSDVDISD--LNKASVIIP---GPLPVSTQDTSS-----------------------------------------------TNPTTEPNTATQMLL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10035-1", "uniprot_id": "HMH2_DROME", "id": "P10035-1", "name": "Homeobox protein H2.0", "aln": "MLLHESAASMEQSMPENLSTHMYGECEVNPTLAKCPDPVNVDHELPTKESCASTTIVSTSPTSATSTTKVKLSFSVDRLLGSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANAESRRFGHATLPPTFTPTSSHTYPFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKS-GQEKQPSAVP-----ESGGVFKTSTPS-------GDGTPQEALDYSSDSCSSVDLSEQADEDDNIEINVVE----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: ..*:* . *. . :* .* * . : *: .. .: . * * . : . :.. .. .: . . *... .. . .: *: . : : : :. :. . : : . : : . .: . :.: . ::. . . : *: * : : .. ******************** :*: ***:*****::*** *.*******************::* . .::*: . . * : : .* :: .... . .: :: .. .: ", "identical_positions": 69, "similar_positions": 107, "identity": "13.61%" }, { "cls_id": "homologset.agr.FB:FBgn0001179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G005-1", "uniprot_id": "ERCC3_RAT", "id": "Q4G005-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDAPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTVE-GSGGASTSQGVDAQAK------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDSLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRFGTMSSLSGADDTVYMEYHSSR-NKAST-KHVHPLFKRFRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49135-1", "uniprot_id": "ERCC3_MOUSE", "id": "P49135-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDIPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTAAEGSGGPSTSQGVDAQAT------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRCGTMSSLSGADDTVYMEYHSSR-SKASS-KHVHPLFKRFRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19447-1", "uniprot_id": "ERCC3_HUMAN", "id": "P19447-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRADR--DKKKSRKRHYED-EED----DEEDAPGNDPQEA--------------VPSAAGK--QVDESGTKVDEYGAKD-----------------------YR----LQMPLKDDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAE-SSGGPSTSRVTDPQGK------SDIPMDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSSQASRRFGTMSSMSGADDTVYMEYHSSR-SKAPS-KHVHPLFKRFRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVV1-1", "uniprot_id": "ERCC3_DANRE", "id": "Q7ZVV1-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--RKDKSDR--EKK-SKKRYYED-EEE----DEE-VIGGESQEA--------------VPAAAGK--QVDESSTKLDEYGAKD-----------------------YR----LQMLLKNDHSSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAISEPVCRPTHAHEYKLTAYSLYAAVSVGLQTSDIIEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKHNRYFVESAFPDVIQRLLQDTVIRDCRLRSAEGEETELITETISSKSAISKSQQ-DNGGPSSSQPADGQRSG-----TQVPEDIFSYYEQMDKEEEEEEET--QTVSFEIRQEMIEELQKRCIQLEYPLLAEYDFRNDTVNPDINMDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWMKSQEWGLIILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLMFSTRDEQQQLLQKVLAASD--------LDAEEEVVMGEVG---GKP-QFSRRAGTMSSMSGADDALYMEYQMPRGSKASVGKNIHPLFKRFRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02870-1", "uniprot_id": "ERCC3_DROME", "id": "Q02870-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MGPPKKSRKDRSGGDKFGKKRRAED-EAFTQLVDDNDSLDATESEG--------------IPGAASKNAETNDEQINTDEYGAKD-----------------------YR----SQMQLRPDHGNRPLWVAP-NGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLTAYSLYAAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEVLQKLLKDPVIQKCRLIRSEGE--DFIQGTLDGK-AITQFGTKLPPGATDKPTPDPAAAAGADGTTAVPEDITDFYEKIDKEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPDINIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWKQQFKMWSTADDSMICRFTSEAKDK-PMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQEWGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWLELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYSYKVITHLKGMDTDSDLMYGTQEEQGQLLQLVLSASD--------LDCEDEKLPGEPGYRPSGSGGAVRRVGGLSSMSGGDDAIYYEHRKKN------IGSVHPLFKKFRG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00578-1", "uniprot_id": "RAD25_YEAST", "id": "Q00578-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2", "aln": "MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMVTGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSLYAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQADILQMLLNDSVIGPLRIDS--------DHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEA------------VFSAVIGGDNEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKR-RNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDADNSVGRGSNG-HKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNK---NKELKEHHPLIRKMYYKNLKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.: . . *: *:: . .*. * * . . :: .*** :* : *: ** .****::* :*:::**:***: : *:***::*:**:.** * ****:*************:* ** . * :***. :.:.*::**: .*:********:***:**:*: .:::* **:*.** *: . : .: : .: . : : . *::.*:*:: . ***: :* :* ::*** :::*:* ******* ***:::****:: :******** ***********:*********:***:**.**::* :** .*.*** **: ** *.* : . . ***: *: ..: ::****: :* :** ::::.* :: :***:::*****.:** *****:: : :*.********:****** ***************:**.::*:**.**********:.***:**: .: *::*** ***.**::*****::**:*.** ***:***:**:.**:::.**:***.*.* **::*****:.* ::****:***.***:*****. ******* ************:****: * :**:**:***:** ** ** *** ***:***::****:* **: :* :.: *: :*** ** .: *.::. *. * * * :*.::*.:* * *: . ***:::: ", "identical_positions": 367, "similar_positions": 214, "identity": "42.28%" }, { "cls_id": "homologset.agr.FB:FBgn0001180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AHZ1-1", "uniprot_id": "Z518A_HUMAN", "id": "Q6AHZ1-1", "name": "Zinc finger protein 518A", "aln": "MPSEQKQLFCDEKQTTLKKDYDVKNEIVDRSAPKPKISGSIHYALKNVKIDLPKINIPNEVLLKHEVDKYRKLFQSKQQTARKSISIKTVSCVEECTLLHKSERAEEEGVKMSAKILNFSCLKCRDNTRYSPNDLQKHFQMWHHGELPSYPCEMCNFSANDFQVFKQHRRTHRSTLVKCDICNNESVYTLLNLTKHFTSTHCVNGNFQCEKCKFSTQDVGTFVQHIHRHNEIHYKCGKCHHVCFTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKYEKRMAKTSAGLKLILKRYKIGASRKTFWKRKKINSGSDRSIEKNTQVLKKMNKTQTKSEDQSHVVQEHLSEEKDERLHCENNDKAPESESEKPTPLSTGQGNRAEEGPNASSGFMKTAVLGPTLKNVMMKNNKLAVSPNYNATFMGFKMMDGKQHIVLKLVPIKQNVCSPGSQSGAAKDGTANLQPQTLDTNGFLTGVTTELNDTVYMKAATPFSCSSSILSGKASSEKEMTLISQRNNMLQTMDYEKSVSSLSATSELVTASVNLTTKFETRDNVDFWGNHLTQSHPEVLGTTIKSPDKVNCVAKPNAYNSGDMHNYCINYGNCELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTAVYENPQRESSSSKTVVQQPISESFLSLVRQESSKPDSLLASISLLNDKDGTLKAKSEIEEQYVLEKGQNIDGQNLYSNENQNLECATEKSKWEDFSNVDSPMMPRITSVFSLQSQQASEFLPPEVNQLLQDVLKIKPDVKQDSSNTPNKGLPLHCDQSFQKHEREGKIVESSKDFKVQGIFPVPPGSVGINVPTNDLNLKFGKEKQVSSIPQDVRDSEKMPRISGFGTLLKTQSDAIITQQLVKDKLRATTQNLGSFYMQSPLLNSEQKKTIIVQTSKGFLIPLNITNKPGLPVIPGNALPLVNSQGIPASLFVNKKPGMVLTLNNGKLEGVSAVKTEGAPARGTVTKEPCKTPILKVEPNNNCLTPGLCSSIGSCLSMKSSSENTLPLKGPYILKPTSSVKAVLIPNMLSEQQSTKLNISDSVKQQNEIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYQNIQPKKPEGTPQRILLKIFNPVLNVTAANNLSVSNSASSLQKDNVPSNQIIGGEQKEPESRDALPFLLDDLMPANEIVITSTATCPESSEEPICVSDCSESRVLRCKTNCRIERNFNRKKTSKKIFSKTKTHGSKDSETAFVSRNRNCKRKCRDSYQEPPRRKATLHRKCKEKAKPEDVRETFGFSRPRLSKDSIRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVSVMKTIAKFNGHVLKVSLSKRTINALLKPVCYNPPKTTYDDFSKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENILKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05084-1", "uniprot_id": "HUNB_DROME", "id": "P05084-1", "name": "Protein hunchback", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNWETTATTNYEQHNAWYNSMFAAN--------IKQEPGHHLDGNS-----------VASSPRQSPIPSTNHLEQFLKQQQQQLQQQPMDTLCAMTPS------------PSQNDQNSLQHYDANLQQQLLQQQQYQQHFQAAQQQHHHHHHLMGGFN----------------PLTPPGLPNPMQHFYGGNLRPSPQPTP--TSASTIAPVAVATGSSEKLQALTP-------------------------PMDVTPPKS---PAKSSQSNIEPE---------------------KEHDQMSNSSEDMKYMAESEDDDTNIR---------------MPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHMKPDKILQCPKCP------------------------------FVTEFKHHLEYHIRKHKN--------------QKPFQCDKCSYTCVNKSMLNSHR-------------------------------------------------------------KSHSSVYQYRCADCDYATKYCHSFKLHLR----------------KYGHKPGMVLDEDGTPNPSLVIDVYG-------------TRRGPKSKNGGPIASGGSGSGS-----------------------------RKSNVAAVAPQQQQSQPAQPVATSQLSAALQ--------------------------------------GFPLVQGNSAPPAASP--------------VLPLPASPAKSVASVEQTPS------------------LPSPANLLPPLASLLQQNRNMAFFPYWNLNLQ-MLAAQQQAAVLAQLSPRMREQLQQQNQQQSDNEEEE----------------QDDEYERKSVDSAMDLSQGTPVKEDEQQ-QQPQQP-------------------LAMNLKVEEEATPLMSSSNASR-----RKGRVLKLDTLLQLRSEAMTSPEQLKVPSTPMPTASSP-------------------------------------------------------------------IAGRKPMPEEHCSGTSSADESMETAHVPQANTS--------------------------------ASSTASSSGNSSNASSNSNGNSSSNSSSNGTTSAVAAPPSGTP---------------AAAGAIYECKYCDIFFKDAVLYTIHMGYHSCD----DVFKCNMCGEKCDGPVGLFVHMARNAHS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* . .: ** :*.:. * * :**. :* .:: *: : . *.: :::*::: :. * *.: .*:: . :: ::. ::.: :: * :::: :* : ..: *:: . * : . *.*:. *.. . .*:.:. .::.:.*. . .:: *::* :* .* * .**.. :*::*: * :* **. :. *.**.: * * .: : :. * . : :****.: *: :*: : *.* . :. : * :* .: * ::* : ...* * *::.: :*. ..:*. :: .*. .: *.*: : **.: *...*** .* :. : :. * :. *:..*. * . * *...:: *.:: :* :...:* *: * *:*:: **: * . * **.* . :.*::*: : *. * * *.* : . .* . .* *: : ::* * * *.* .: *. : : **. ::: :: : : : . :* : . *::. * **::* * **.*.:.*:.* ... .*. .: . . *:* * .: *.: * : ..::. * :*. . **. ..:*. .:..:: ** ..:.. * ..: *.. . :: :: **: . * *: * .*: * . .* ...:: * .: :*.: . :: :.: *:* :**. *. * *: . ", "identical_positions": 152, "similar_positions": 312, "identity": "10.25%" }, { "cls_id": "homologset.agr.FB:FBgn0001186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19367-1", "uniprot_id": "HXK1_HUMAN", "id": "P19367-1", "name": "Hexokinase-1", "aln": "---------MIAAQLLAYYFTELK--DDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS--SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLR-----KQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKK--RTVEMHNKIYAIPIEIMQGT---GEELFDHIVSCISDFLDYMGIK--------GPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEP-----------TCEVGLIVGTGSNACYMEEMKNVEMVEGD------QGQ---MCINMEWGAFGDNGCLDDIRTHYDRLVDEY-SLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFR-----GQISETLKTRGIFETKFLSQIESDRLA-LLQVRAILQQLGLNSTCD-DSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELS-------PKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52789-1", "uniprot_id": "HXK2_HUMAN", "id": "P52789-1", "name": "Hexokinase-2", "aln": "---------MIASHLLAYFFTELN--HDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGT--NFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLS-----KETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKW--GGVEMHNKIYAIPQEVMHGT---GDELFDHIVQCIADFLEYMGMK--------GVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDP-----------HCEVGLIVGTGSNACYMEEMRNVELVEGE------EGR---MCVNMEWGAFGDNGCLDDFRTEFDVAVDEL-SLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFR-----GRISERLKTRGIFETKFLSQIESDCLA-LLQVRAILQHLGLESTCD-DSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLA-------PKCDVSFLQSEDGSGKGAALITAVACRIREAGQR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2TB90-1", "uniprot_id": "HKDC1_HUMAN", "id": "Q2TB90-1", "name": "Hexokinase HKDC1", "aln": "---------MFAVHLMAFYFSKLK--EDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGS--KFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLK-----KKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGR---RSVRMYNKIFAIPLEIMQGT---GEELFDHIVQCIADFLDYMGLK--------GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDP-----------NCEIGLIAGTGSNMCYMEDMRNIEMVEGG------EGK---MCINTEWGGFGDNGCIDDIWTRYDTEVDEG-SLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFR-----GQISERLRTRGIFETKFLSQIESDRLA-LLQVRRILQQLGLDSTCE-DSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELA-------PRCDVTFMLSEDGSGKGAALITAVAKRLQQAQKEN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52790-1", "uniprot_id": "HXK3_HUMAN", "id": "P52790-1", "name": "Hexokinase-3", "aln": "MDSIGSSGLRQGEETLSCSEEGLPGPSDSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIRRQGAYNIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCVSVEWGSFSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCGVLFGGCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASDVELVQHVCAAVCTRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVLQGTVMLLAPECDVSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLR-----GEAS---SLRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG------VQITSEIYSIPETVAQGS---GQQLFDHIVDCIVDFQQKQGLS--------GQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDP-----------RCEIGLIVGTGTNACYMEELRNVAGVPGD------SGR---MCINMEWGAFGDDGSLAMLSTRFDASVDQA-SINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFR-----GQQIQRLQTRDIFKTKFLSEIESDSLA-LRQVRAILEDLGLPLTSD-DALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFSSLVAATVRELA-------PRCVVTFLQSEDGSGKGAALVTAVACRLAQLTRV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52792-1", "uniprot_id": "HXK4_MOUSE", "id": "P52792-1", "name": "Hexokinase-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDDRARMEATKKEKVEQILAEFQLQEEDLKKVMSRMQKEMDRGLK-----LETHQEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGT---AEMLFDYISECISDFLDKHQMK--------HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDR-----------QCEVGMIVGTGCNACYMEEMQNVELVEGD------EGR---MCVNTEWGAFGNSGELDEFLLEYDRMVDES-SVNPGQQLYEKIIGGKYMGELVRLVLLKLVEENLLFH-----GEASEQLRTRGAFETRFVSQVESDSGD-RRQILNILSTLGLRPSVA-DCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT-------PNCEITFIESEEGSGRGAALVSAVACKKACMLGQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17712-1", "uniprot_id": "HXK4_RAT", "id": "P17712-1", "name": "Hexokinase-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDDRARMEATKKEKVEQILAEFQLQEEDLKKVMSRMQKEMDRGLR-----LETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGT---AEMLFDYISECISDFLDKHQMK--------HKKLPLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDR-----------QCEVGMIVGTGCNACYMEEMQNVELVEGD------EGR---MCVNTEWGAFGDSGELDEFLLEYDRMVDES-SANPGQQLYEKIIGGKYMGELVRLVLLKLVDENLLFH-----GEASEQLRTRGAFETRFVSQVESDSGD-RKQIHNILSTLGLRPSVT-DCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT-------PNCEITFIESEEGSGRGAALVSAVACKKACMLAQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35557-1", "uniprot_id": "HXK4_HUMAN", "id": "P35557-1", "name": "Hexokinase-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLR-----LETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGT---AEMLFDYISECISDFLDKHQMK--------HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDH-----------QCEVGMIVGTGCNACYMEEMQNVELVEGD------EGR---MCVNTEWGAFGDSGELDEFLLEYDRLVDES-SANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFH-----GEASEQLRTRGAFETRFVSQVESDTGD-RKQIYNILSTLGLRPSTT-DCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT-------PSCEITFIESEEGSGRGAALVSAVACKKACMLGQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W330-1", "uniprot_id": "Q9W330_DROME", "id": "Q9W330-1", "name": "Phosphotransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRELN---------------------------------------GAMKSVSINSAQLNG------HNNGGGLDETDRVGVAQGAALSATEKITTTTAAATKSATATTNATTATATTTNLTTHSPQQ-------------------------------------------------IALLSAAE-----KSKMVHELCQQLLLTDEQVQELCYRILHELRRGLA-----KDTHPKANVKCFVTYVQDLPNGNERGKFLALDLGGTNFRVLLIHLQENND----FQMESRIYAIPQHIMIGS---GTQLFDHIAECLSNFMAEHNVY--------KERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMSCAWKNH-----------NCKIGLIVGTGANACYMERVEEAELFAAE------DPRKKHVLINTEWGAFGDNGALDFVRTEFDRDIDVH-SINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFN-----GQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLINKMDEP------TVTVGVDGSVYRFHPKFHNLMVEKISQLIK------PGITFDLMLSEDGSGRGAALVAAVACREDILNGKK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04806-1", "uniprot_id": "HXKA_YEAST", "id": "P04806-1", "name": "Hexokinase-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLT--KKGGN------IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHT----FDTTQSKYKLPHDMRTTK--HQEELWSFIADSLKDFMVEQELLNTKD------TLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRELP-IEIVALINDTVGTLIASYYTDP-----------ETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPS--NSPMAINCEYGSFDN-EHLVLPRTKYDVAVDEQ-SPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLK-----DQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQK------RGYKTGHIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKSLGIIGA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04807-1", "uniprot_id": "HXKB_YEAST", "id": "P04807-1", "name": "Hexokinase-2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLS--KKGGN------IPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRT----FDTTQSKYRLPDAMRTTQ--NPDELWEFIADSLKAFIDEQFPQGISE------PIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRNIP-IEVVALINDTTGTLVASYYTDP-----------ETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPP--SAPMAINCEYGSFDN-EHVVLPRTKYDITIDEE-SPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFK-----NQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQK------RGYKTGHIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKSVGIIGA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P17709-1", "uniprot_id": "HXKG_YEAST", "id": "P17709-1", "name": "Glucokinase-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFDDLHKATER---------AVIQAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAADLGGTNFRICSVNLHGDHT----FSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAK-GKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDN-ELKHLPTTKYDVVIDQKLSTNPGFHLFEKRVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPTTPTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLRHALALSP---LGAEGERKVHLKIAKDGSGVGAALCALVA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04409-1", "uniprot_id": "EMI2_YEAST", "id": "Q04409-1", "name": "Putative glucokinase-2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFENLHKVNAE---------ALEDAVVEICSSLQVDAAKLDELTAYFIECMEKGLNNTSVGEEKTVDKGLPMIPTYVTSLPNGTERGVLLAADLGGTHFRVCSVTLNGDGT----FDMQQLKSKIPEEYLNDKDVTSEELFSYLGRRTRAFVRKHHPELLKSTGENIKPLKMGFTFSYPVDQTSLSSGTLIRWTKSFKIEDTVGKDVVRLYQEQLDIQGLSMINVVALTNDTVGTFLSHCYTSG-SRPSSAGEISEPVIGCIFGTGTNGCYMEDIENIKKLPDELRTRLLHEGKTQMCINIEWGSFDN-ELKHLSATKYDIDIDQKFSPNPGYHLFEKRISGMYLGELLRNILVDLHARGLILGQYRNYDQLPHRLKTPFQLCSEVLSRIEIDDSTNLRETELSFLQSLRLPTTFEERKAIQNLVRSITRRSAYLAAVPIAAILIKTNALNKRYHGEVEIGFDGYVIEYYPGFRSMLRHALALSP---IGTEGERKIHLRLAKDGSGVGAALCALVA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : : : ** : : :* * *.* * *: *****::*: : : . . :* *: .: * : :*****:* : : . * ***.* . ..::* : :. : : :.: *: ***..* :: : . :* * *** * .: : . . : :* *:*.*.: .:* :* * ..* : :** .* ::**::* *: : ..:: . : : : :.:* * : : : : : : *:* : :* : : :. ** : . :* * : . : :::*** ***: : :. ", "identical_positions": 70, "similar_positions": 113, "identity": "7.08%" }, { "cls_id": "homologset.agr.FB:FBgn0001197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0S6-1", "uniprot_id": "H2AZ_MOUSE", "id": "P0C0S6-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C0S5-1", "uniprot_id": "H2AZ_HUMAN", "id": "P0C0S5-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0S7-1", "uniprot_id": "H2AZ_RAT", "id": "P0C0S7-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71PD7-1", "uniprot_id": "H2AV_DANRE", "id": "Q71PD7-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q71UI9-1", "uniprot_id": "H2AV_HUMAN", "id": "Q71UI9-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3THW5-1", "uniprot_id": "H2AV_MOUSE", "id": "Q3THW5-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08985-1", "uniprot_id": "H2AV_DROME", "id": "P08985-1", "name": "Histone H2A.v", "aln": "MAG---GKAGKDSGK--AKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12692-1", "uniprot_id": "H2AZ_YEAST", "id": "Q12692-1", "name": "Histone H2A.Z", "aln": "MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVE------KKGSKK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* * **...* .. :: * * ***********:*:** ::*.: ***:.**:* :*:***************:********************:******:****.***:***:*:*: * :: ", "identical_positions": 84, "similar_positions": 29, "identity": "57.53%" }, { "cls_id": "homologset.agr.FB:FBgn0001202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWS4-1", "uniprot_id": "A0A8I5ZWS4_RAT", "id": "A0A8I5ZWS4-1", "name": "Protein Hook homolog 3", "aln": "--MFNVESVERVELCESLLTWIQTFNVDTPCQTVEDLTNGVVMSQVLQKIDPAYFDDNWLNRIKT-EVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQILMERLNQSD----------SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARGQLETYKRQVVELQNRLSDESKKADKLDFEYKRLKEKVDGLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKINQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAED--SVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNN-SSLRIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQG--AAPEIQALKNQLQERDRLFHSLEKEYEKTKTQRDMEEKYIVSAWYNMGMTLHKKAAEDRLAS----------TGSGQSFLARQRQATSTRRSYPGHVQPATARSCSSRML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUK6-1", "uniprot_id": "HOOK3_MOUSE", "id": "Q8BUK6-1", "name": "Protein Hook homolog 3", "aln": "--MFNVESVERVELCESLLTWIQTFNVDAPCQTAEDLTNGVVMSQVLQKIDPVYFDDNWLNRIKT-EVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGHDAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQILMERLNQSD----------SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARGQLETYKRQVVELQNRLSDESKKADKLDFEYKRLKEKVDGLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEDSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAED--SVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNN-SSLRIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQG--AAPEIQALKNQLQERDRLFHSLEKEYEKTKSQRDMEEKYIVSAWYNMGMTLHKKAAEDRLAS----------TGSGQSFLARQRQATSTRRSYPGHVQPATAR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VS8-1", "uniprot_id": "HOOK3_HUMAN", "id": "Q86VS8-1", "name": "Protein Hook homolog 3", "aln": "--MFSVESLERAELCESLLTWIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKT-EVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSD----------SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAED--SVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNN-SSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQG--AAPEIQALKNQLQERDRLFHSLEKEYEKTKSQREMEEKYIVSAWYNMGMTLHKKAAEDRLAS----------TGSGQSFLARQRQATSSRRSYPGHVQPATAR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZB48-1", "uniprot_id": "D3ZB48_RAT", "id": "D3ZB48-1", "name": "", "aln": "MEDPQPLPQPELPLCDSLIIWLQTFKTASPCQDVKQLTNGVTMAQVLHQIDVAWFSESWLSRIKD-DVGDNWRIKASNLKKVLHGITSYYHEFLGQQISEELIPDLNQITESSDPVELGRLLQLILGCAVNCEKKQEHIKNIMTLEESVQHVVMTAIQELMSKEIVSSPASDAVGELEQQLKRALEELQEALAEKEELKQRCQELDMQVTALQDEKNSLVSENEMMNEKLDQLDG---------SFDDPNTMVAKKYFHVQLQLEQLQEENYRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEVYRQKLQDLNDLRKQVKSLQETNMMYMHNTVSLEEELKKANAARAQLETYKRQVQDLHTKLSSESKRADTLAFEMKRLEEKHETLLKEKERLIEQRDTLKETNEELRCSKAQQDHLNQADSSATKS---YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGTENERIEQLQEQLEQKHRKMNELETEQRLSKERIGELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDISQ-NAQKISELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNP---ASAEIMLLRKQLAEKDRRIEILESECKVAK-FRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGASACKDSVAAAPARSFLAQQRHITSTRRNLSVKVPAAASD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIL5-1", "uniprot_id": "HOOK1_MOUSE", "id": "Q8BIL5-1", "name": "Protein Hook homolog 1", "aln": "MEDPQPLPQSELPLCDSLIIWLQTFKTASPCQDVKQLTNGVTMAQVLHQIDVAWFSESWLSRIKD-DVGDNWRIKASNLKKVLHGITSYYHEFLGQQISEELIPDLNQITECADPVELGRLLQLILGCAVNCEKKQEHIKNIMTLEESVQHVVMTAIQELMSKEIVISPASDTVGELEQQLKRALEELQEAIAEKEELKQRCQELDMQVTTLQDEKNSLVSENEMMNEKLDQLDG---------SFDDPNTMVAKKYFHVQLQLEQLQEENYRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEVYRQKLQDLNDLRKQVKSLQETNMMYMHNTVSLEEELKKANAARAQLETYKRQVQDLHTKLSSESKRADTLAFEMKRLEEKHETLLKEKERLIEQRDTLKETNEELRCSKAQQDHLNQADASATKS---YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGTENERIEQLQEQLEQKHRKMNELETEQRLSKERIGELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDISQ-NAQKISELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNP---ASAEIMLLRKQLAEKERRIEILESECKVAK-LRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGASACKDSVAAAPARSFLAQQRHITNTRRNLSVKVPAAASD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJC3-1", "uniprot_id": "HOOK1_HUMAN", "id": "Q9UJC3-1", "name": "Protein Hook homolog 1", "aln": "MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKE-DVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDG---------SFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKS---YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQ-NVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNP---ASAEIMLLRKQLAEKERRIEILESECKVAK-FRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPARSFLAQQRHITNTRRNLSVKVPATTSD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZ80-1", "uniprot_id": "HOOK1_DANRE", "id": "Q5TZ80-1", "name": "Protein Hook homolog 1", "aln": "------MDLKKTVLCESLIIWLQTFKTAAPCKTVEDLTSGAAMSQALHQIDPSWFSESWLARIKE-DVGDNVRLKMNNLKKILQMIVDYYNEVLAQQMSDFPLPDLMRVVEQSDQVELGRLLQLILGCAVKCDRKQEYIQIIMTLEESVQHVVMTAIQELMSRESVSQLGAEPAGDTEQQLKKALEDLTEVMAEKEELAQRCQELDMQVTVLQEERNSLLAENDLLTDRSSQLE----------TFDDPSTPSGRKHSQLQFQLEQLQEENFRLEAAKDDYRIHCEELEKQLVELQHRNDELTSLAEESRSLKDELDILRSCSDRAVKLEASVETYRKKLEDLSDLRRQMKALEEKNMTYMHNTVSLEEELRKANAARAQLETYKRQVQELHKKLSDESRRADNLVFEMKKLQEKYDALVKERERISIERDTLRETNEELRCTQAQQDQLLLAGKYQTGSP-SHDNLAAEMLPIEYREKFIRLQHENKMLRLQQEESEKQRITELQQQLEEARRGRSQLDTDNRLNRERISELQQQVEDLQKALQTQGAKPD---DSHLKRKLDAHMVQLNEAQDEIMKKKELLEDLQPDATQ-TSVKMDELMAALKKKDEDMRAMEDRYKMYLEKARDVIRALDPKLNP---ASAEIQSLKVQLSDKDKKIIALERECEQAK-LREYEEKLIVTAWYNKSLNFQKMAIESRLSG-----RANSLVPPGQSFLAQQRQVTNARRTMSINVPASSSK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PTX3-1", "uniprot_id": "E9PTX3_RAT", "id": "E9PTX3-1", "name": "", "aln": "------MSMDKAELCGSLLTWLQTFQVSPPCASPQDLSSGLAIAHVLNQIDPSWFNDAWLQGISE-DPSPSWRLKVRKLERILQSLVEYSKDVLGHPVSHQHLPDVSLIGEFSNPAELGKLLQLVLACAISCEKKQEYIQRIMMLEESVQHVVMEAIQELMTKDTPDSLSPENYGNFDTQSRR-YYFLSEEVEEGGDLQQHYLDLERQLVLLSEEKQSLAQENAALRERVGRSE----------VESASG-LTAKKLLLLQSQLEQLQEENFRLESSREDERLRCVELEREVAELQQRNQALASLSQEAQALKDEMDELRQSSERARQLEATLNSCRRRLGELQELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQMQELQGQWQEEAMKAEKWLFECQNLEEKCDLLTKEKERLLTERDSLRETNEELRCAQLQPRGLNQAGLSLDPTPSGLENLAAEILPAELRETLVRLQLENKRLCQQ-EAADRERQEELQRHLEEANRARHGLEAQQRLNQQQLSELRAQVEELQKALQEQGGKTDDAAPTLLKRKLEDHLQKLHEADLELQRKREYIEELEPPTDSNTARRIEELQDSLQKKDADLRAMEERYRRYVDKARTVIQTLEPKQRPPSVVSPEFHTLRSQLWERNMRIRQLEMDYEKSRSRQEQEEKLLISAWYSMGMALEHRAGEEH------------APAHAQSFLAQQRLATNARRGPLGRQASLSLRPTDKH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMK6-1", "uniprot_id": "HOOK2_MOUSE", "id": "Q7TMK6-1", "name": "Protein Hook homolog 2", "aln": "------MSVDKAELCGSLLTWLQTFQVSPPCASPQDLSSGLAIAHVLNQIDPSWFNNEWLQGISE-DSSPSWRLKVRKLEKILQSLVEYSKNVLGHPVSDQHLPDVSLIGEFSNPAELGKLLQLVLGCAISCEKKQEYIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPENYGNFDTQSRR-YYFLSEEVEEGDHLQQHYLDLERQLLLLSEEKQNLAQENAALRERVGRSE----------VESAPG-LTAKKLLLLQSQLEQLQEENFRLESSREDDRLRCLELEREVAELQQRNQALTSLSQEAQALKDEMDELRQSSERARQLEATLNSCRRRLGELQELRRQVRQLEERNAGHAERTRQLEEELRRAGSLRAQLEAQRRQVQELQGQWQEEAMKAEKWLFECRNLEEKCDLVTKEKERLLTERDSLREANEELRCAQLQPRGLAQADLSLDPTPSGLENLAAEILPAELRETLVRLQLENKRLCQQ-EAADRERQEELQRHLEEANRARHGLEAQQRLNQQQLSELRAQVEELQKALQEQGGKTED--PTLLKRKLEDHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQDSLQKKDADLRAMEERYRRYVDKARTVIQTLEPKQRPPTVVSPEFHTLRSQLWERNLRIRQMEMDYEKSRRRQEQEEKLLISAWYSMGMALEHRAGEEH------------APAHAQSFLAQQRLATNARRGPLGRQA-LSLRPTDKH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96ED9-1", "uniprot_id": "HOOK2_HUMAN", "id": "Q96ED9-1", "name": "Protein Hook homolog 2", "aln": "------MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISE-DPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRR-YYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPE----------GEGTPG-LTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQ-EAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEER------------APAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9W9-1", "uniprot_id": "A0AB13A9W9_DANRE", "id": "A0AB13A9W9-1", "name": "", "aln": "------MSLNKHQLSDSLFIWLQSFQVPS-CASKHELTSGVAIAHVLNKIDSTWFNETWLSRIKE-DGGTNWRLKVSNLKKILQSMMEYYHDVLSQQVSDEHVPDVCLIGEMGDVTELGRLLQLVLGCAVSCDRKQEHIQQIMMLEESVQHVVMTAIQELLTKDPAEPGTPETYGDFDSQSRK-YYFLSEEPDDRDSTSQRCRELQQQLSVLMEEKSCLQVEVQSLRERVSHCEP---------SDVSST-ITNKKLLLLQSQMEQLQEENYRLENSRDDLRVRAEVLEREVMDLQIRNEDLTSLAQEAQALKDEMDILRHSSDRVSRLEAMVETYKRKLEDLGDLRRQVRLLEERNHVYMQRTCELEEEQRRATAIRSQLDSYKRQAHEMSAKHSAEAMKAEKWQFEYKNLNDKYETLLKEREKLISERDTLRETTEELRCAQVQQQCLTDS---MIGDAGAVGSLASEIMPTEFRDTVVRLQQENKMLCVQ-EESYRHRLEELQTQLEEAQRRQNTLETQNRLSQQQISDLSAQVEELQRALQEQDSRNEDVISSLLKKKLEEHLEKLHEAHSDLQKKREVIDDLEPPVDINMAKKVDELQEILKKKDEDMRRMEDRYKRYVEKARTVIKTLEPKQK-LNPVPVEVQALKNQLSEKDRKIQHLEHDFEKTRSRHDQEEKLIISAWYNMGMALHQRVAGERSSS---------SSSSAQSFLAQQRQSTQARRG----FSRLQPR-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24185-1", "uniprot_id": "HOOK_DROME", "id": "Q24185-1", "name": "Protein hook", "aln": "------MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSNWRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQSYITEIMCLEEELQANIMRALQELEATRQASTPEGGVASSLSRGSRTGLLDSKAVQEDRDALAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRRQLDLLKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLDAESSKNVKLEFDNKNLESKNLALQRAKDSLLKERDNLREAVDELKCGQLSSNTALTG-----------TTVSRELQPSATVEKLQRLEAENKALREG-----QGGQTALAQLLDDANKRCENLREQLKTANERILSLSHASQSDDPILK------------------ESEFGKQIKQLMELNEQKTLQLEEAVTQSTSLQCKVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRIAS---------ALDASVLEKSADLVEEEPKP----KMSVMEEQLMTSAFYRLGVNAQRDAIDSKLAI---------LMGSGQTFLARQRQSAPRKSLSAMKSK------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : **: *::::: . ..*:.* .:: .*::: * : ** *. . . ::: ::: : : : .* :.* :.. **: : * : ** ::***:*.**:.* .**.:* ** :**.:* :* *:*** : . . : *: : : :: * :*: * * : :. : : . : : *:: *:** : * .::* :::. : :: .:: : : * . : * :****:* ** .:: *. : :::* : :*::*:: *:* . : ... .:*:: :: : *:: ::: :: : . *: : . *: :.*:.* : : :: : :**.*:*: :**:* : . .:: *: . : . **: *** * . * *:: . * : : .::: .: :. : *: : .: : : :: .:: : :: :* * :: :: : :*: ::**: *:::::*: * .: ::. : * . **: : :*:* .: .: .: .::***:** : : ", "identical_positions": 105, "similar_positions": 232, "identity": "13.94%" }, { "cls_id": "homologset.agr.FB:FBgn0001208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04176-1", "uniprot_id": "PH4H_RAT", "id": "P04176-1", "name": "Phenylalanine-4-hydroxylase", "aln": "MAAVVLENGVLSRKLSDFGQETSYIED--NSNQNGAISLIFSLKEE---VGALAKVLRLFEENDINLTHIESRPSRLNKDEYEFFTYLDKRTKPVLGSIIKSLRNDIGATVHELSRDKEKNT--VPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTEEEKQTWGTVFRTLKALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKEGDSIKAYGAGLLSSFGELQYCLSDKPKLLPLELEKTACQEYSVTEFQPLYYVAESFSDAKEKVRTFAATIPRPFSVRYDPYTQRVEVLDNTQQLKILADSINSEVGILCNALQKIKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16331-1", "uniprot_id": "PH4H_MOUSE", "id": "P16331-1", "name": "Phenylalanine-4-hydroxylase", "aln": "MAAVVLENGVLSRKLSDFGQETSYIED--NSNQNGAVSLIFSLKEE---VGALAKVLRLFEENEINLTHIESRPSRLNKDEYEFFTYLDKRSKPVLGSIIKSLRNDIGATVHELSRDKEKNT--VPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTEEERKTWGTVFRTLKALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKEGDSIKAYGAGLLSSFGELQYCLSDKPKLLPLELEKTACQEYTVTEFQPLYYVAESFNDAKEKVRTFAATIPRPFSVRYDPYTQRVEVLDNTQQLKILADSINSEVGILCHALQKIKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00439-1", "uniprot_id": "PH4H_HUMAN", "id": "P00439-1", "name": "Phenylalanine-4-hydroxylase", "aln": "MSTAVLENPGLGRKLSDFGQETSYIED--NCNQNGAISLIFSLKEE---VGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDT--VPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17276-1", "uniprot_id": "PH4H_DROME", "id": "P17276-1", "name": "Protein henna", "aln": "-----MYQRQVSFDKPTRVEDSAYIVEGVDIKEARNTCLLFSPKDSSLSSGALANILAIFKKHDINLVHIESRSS-LRVPGYEFFVEADGKS-GALGKAIEDVKEQC-SYFNIISRDYKDNATAVPWFPRRIRDLDRFANQILSYGSELDADHPGFTDPEYRKRRKYFADIAYNYKHGEPLPHVDYTKEEIETWGIIFRNLTKLYKTHACREYNHVFPLLVDNCGFREDNIPQLEDVSNFLRDCTGFTLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHPSKPMYTPEPDVCHELMGHVPLFADPAFAQFSQEIGLASLGAPDDYIEKLSTIFWFTVEYGVCRQEGELKAYGAGLLSSYGELEYCLTDKPQLKDFEPEVTGVTKYPITQFQPLYYVADSFETAKEKTIKFANSIPRPFGVRYNAYTQSVEVLDSKPQISNLMDNINSEFQILQNAVAKLRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. . . ::::** : : :: .*:** *:. ****::* :*:::::**.*****.* *. ****. * :: .* . *: ::.: : .: :*** :.:: ****** *::************:*********.** ** *** ********:**:*:*:*:* :** :*** :*:.*. ******* *:**:**** . ***:***********:**: **** **************.********.****** **********:****:******:* :*****************:*****:**:*****:*:*:: ..:**********:***:***::**:* :* * *. :*.:*:********:**. ****. .** :*****.***:.*** :****.. *:. * *.****. ** *: *:: ", "identical_positions": 267, "similar_positions": 113, "identity": "58.04%" }, { "cls_id": "homologset.agr.FB:FBgn0001215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6URK4-1", "uniprot_id": "ROA3_RAT", "id": "Q6URK4-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "---MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQR-GRGG--------GSGNF-MGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYN---GFGGD-------GGNYGGGPG-YSS-----RGGYGGGGPGYGNQGGGYGGG-------------------------GGGYDGYNE-----------GGNFGGGN----YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGG------RSSGSPYGGG----------YGSGG--------GSGG--YGSR----RF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG05-1", "uniprot_id": "ROA3_MOUSE", "id": "Q8BG05-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "---MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQR-GRGG--------GSGNF-MGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYN---GFGGD-------GGNYGGGPG-YSS-----RGGYGGGGPGYGNQGGGYGGG-------------------------GGGYDGYNE-----------GGNFGGGN----YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGG------RSSGSPYGGG----------YGSGG--------GSGG--YGSR----RF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51991-1", "uniprot_id": "ROA3_HUMAN", "id": "P51991-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "---MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAG----SQR-GRGG--------GSGNF-MGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYN---GFGGD-------GGNYGGGPG-YSS-----RGGYGGGGPGYGNQGGGYGGG-------------------------GG-YDGYNE-----------GGNFGGGN----YGGGGNYNDFGNYSGQQQSNYGPMKGG-SFGG------RSSGSPYGGG----------YGSGG--------GSGG--YGSR----RF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P4F7-1", "uniprot_id": "A0A8M1P4F7_DANRE", "id": "A0A8M1P4F7-1", "name": "", "aln": "-------------------------MESRDSKEPEQLRKLFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSEVDAAMTARPHKVDGRVVEPKRAVSREDSNKPGAHLTVKKIFVGGIKEDTEEYHIREYFECYGKIETIDIMEERSTGKKRGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQEMQSSS----NQR-YRGG--------GGGNF-TGRGGNFG--------------RGGYGGGR-------GGGDG-YN---GFGG----------NYGGGPGGYGGG----RGGYGGG-PGYGNQGG--GGG-------------------------FGGFDNYNDRGN-------FGGNFGGGGGSSGGGGGGNYNDFGNYGGQQ-SNFGPMKGN-NFGG------RNSGPYGGGG----------YGSGG--------GGGGGGYGSR----RY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A7VJC2-1", "uniprot_id": "ROA2_RAT", "id": "A7VJC2-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-----------------MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIFLQKYHTINGHNAEVRKALSRQEMQEVQ----SSRSGRGGNF------GFGDS-RGGGGNFGPGPGSNFRG----GSDGYGSGR-------GFGDG-YN---GYGGGP-----GGGNFGGSPG-YGGG----RGGYGGGGPGYGNQGGGYGGG-------------------------YD--------------------NYGGGN-----YGSGNYNDFGNY-NQQPSNYGPMKSG-NFGGS-----RNMGGPYGGGN---------YGPGG--------SGGSGGYGGRS---RY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22626-1", "uniprot_id": "ROA2_HUMAN", "id": "P22626-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-----------------MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQ----SSRSGRGGNF------GFGDS-RGGGGNFGPGPGSNFRG----GSDGYGSGR-------GFGDG-YN---GYGGGP-----GGGNFGGSPG-YGGG----RGGYGGGGPGYGNQGGGYGGG-------------------------YD--------------------NYGGGN-----YGSGNYNDFGNY-NQQPSNYGPMKSG-NFGGS-----RNMGGPYGGGN---------YGPGG--------SGGSGGYGGRS---RY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88569-1", "uniprot_id": "ROA2_MOUSE", "id": "O88569-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-----------------MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQ----SSRSGRGGNF------GFGDS-RGGGGNFGPGPGSNFRG----GSDGYGSGR-------GFGDG-YN---GYGGGP-----GGGNFGGSPG-YGGG----RGGYGGGGPGYGNQGGGYGGG-------------------------YD--------------------NYGGGN-----YGSGSYNDFGNY-NQQPSNYGPMKSG-NFGGS-----RNMGGPYGGGN---------YGPGG--------SGGSGGYGGRS---RY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PGI6-1", "uniprot_id": "A0A8M1PGI6_DANRE", "id": "A0A8M1PGI6-1", "name": "", "aln": "-----------------------MSKEGQ-PREPEQLRKLFIGGLSFETTDDSLRAHFEQWGTLTDCVVMKDPNTKRSRGFGFVTYSSVDEVNASMDARPHKVDGRLVEPKRAVSREDSSKPFAHTTVKKIFVGGIKDDTEENHLRDYFDQFGKIEVVEIMVDHKTGNKRGFAFVTFDDHDSVDRIVIQKYHTVNGHNCEVRKALSKQEMANTGRGGGGGGGGGGGNFNRYGNNGGYNNDFGGGGGGGNRDGYFGRGGRGNNFGGGGGGGG-----YGGGGDCYNNNNGFGGGG--YGGGGGNGGGSPGNYGGNRGYG--GGGGGGHGYGNQGGGYGGGN--------------------SGGGGGGYNNYNNGNGNFGGGNFGGGGGGGGN----SGGGGNYNDFGNYNSQQS-NYGPMKG--NFGGGG-----RNSGPYGGGYG--------GGSSG-------SGGGGSGYGGGSGGRRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QHJ0-1", "uniprot_id": "A0A8M9QHJ0_DANRE", "id": "A0A8M9QHJ0-1", "name": "", "aln": "MPPAITPKKEREAESAVSHRVTAMSKEQQTPREPEQLRKLFIGGLSFETTDESLRAHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVGEVDAAMDARPHKVDGRAVEPKRAVSREDSSKPGAHSTVKKMFVGGIKEDTDEEHLREYFGQFGKIDEVNIMTEKNSDKRRGFAFITFDDHDAVDRIVIQKYHTVNGHNCEVRKALSREEMNRVSMNSRGGRGGGGG-------SGGGNFGRGGGGGGGGYGGGYGGGG------GRGGGGG-----YGGG-DGYN---GYGGGNGISTDKSGYGGGGP-NYGGNRGYGSGGGGGGGGGYGNQGGGYGGG--------------------------GGYDNYNNNGG--GGG--GGGNFGGGN----FGGGGDYNDFGNYNNQSSSNYGPMKGG-NYGGGGGGGGRSGGGPYGGGYG--------GGSGGGGGYGGGSGGGGGGYGGGSGGRRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49312-1", "uniprot_id": "ROA1_MOUSE", "id": "P49312-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS----SSQRGRSG---------SGNFGGGRGGGFGGN-------------DNFGRGG--------------N----FSGR--------GGFGGSRG--GGG----YGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNYNNQS-SNFGPMKGG-NFGG-------RSSGPYGGGGQYFAKPRNQGGYGG--------SSSSSSYGSGR---RF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09651-1", "uniprot_id": "ROA1_HUMAN", "id": "P09651-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS----SSQRGRSG---------SGNFGGGRGGGFGGN-------------DNFGRGG--------------N----FSGR--------GGFGGSRG--GGG----YGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGG---------SYNDFGNYNNQS-SNFGPMKGG-NFGG-------RSSGPYGGGGQYFAKPRNQGGYGG--------SSSSSSYGSGR---RF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Y4L2-1", "uniprot_id": "RA1L3_HUMAN", "id": "A0A2R8Y4L2-1", "name": "Heterogeneous nuclear ribonucleoprotein A1-like 3", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPDAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS----SSQRGRSG---------SGNFGGGRGGGFGGN-------------DNFGRGG--------------N----FSGR--------GGFGGSRG--GGG----YGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNYNNQS-SNFGPMKGG-NFEG-------RSSGPHGGGGQYFAKPRNQGGYGG--------SSSSSSYGSGR---RF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04256-1", "uniprot_id": "ROA1_RAT", "id": "P04256-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASAS----SSQRGRSG---------SGNFGGGRGGGFGGN-------------DNFGRGG--------------N----FSGR--------GGFGGSRG--GGG----YGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNYNNQS-SNFGPMKGG-NFGG-------RSSGPYGGGGQYFAKPRNQGGYGG--------SSSSSSYGSGR---RF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32P51-1", "uniprot_id": "RA1L2_HUMAN", "id": "Q32P51-1", "name": "Heterogeneous nuclear ribonucleoprotein A1-like 2", "aln": "------------------------MSKSASPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVKGHNCEVRKALPKQEMASAS----SSQRGRRG---------SGNFGGGRGDGFGGN-------------DNFGRGG--------------N----FSGR--------GGFGGSCG--GGG----YGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNYNNQS-SNFGPMKGG-NFGG-------RSSGPYGGGGQYFAKPQNQGGYGV--------SSSSSSYGSGR---RF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJN1-1", "uniprot_id": "A0A8I6GJN1_RAT", "id": "A0A8I6GJN1-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS----SSQRGRNG---------SGNFGG-RGGGFGGN-------------DNFGRGG--------------N----FSGR--------GGFGGSRG--GGG----YGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNYNNQS-SNFGPMKGG-NFGS-------RSSGSYGGGGQYFANPRNQGGYGG--------SSSSSSYGSGR---RF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07909-1", "uniprot_id": "ROA1_DROME", "id": "P07909-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "-------MVNSNQNQNGNSNGHDDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKALPKQNDQQGG---GGGRGGPGGR-------AGGNRGNMGGGNYGNQNGG----------GNWNNGG-------------NNWGNNRGGND---NWGNNSFGGGGG--GGG------GYGGGNNSWGNNNPWDNGN--------------------------------------------GGGNFGGGG----NNWNNGGNDFGGY--QQNYGGGPQRGGGNFNN-------NRMQPYQGGGGFKAG----GGNQGN------YGGNNQGFNNGGNNRRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:: ****.**.:.**::.*: ::*:**.:.* ***:** .**.*****:*:: :: : : **.:*** *******.*:: * * ****:***.:*:* :* :*:** :*:* :::: :: :.::*** *: ***:*.**::. ** * ::.: :*:*** ::: . * : *.. * . . * * .* **. .. * *.* .:**:. . ***. . ****.* *. . ** :. .: . ** * .... :.. *:", "identical_positions": 102, "similar_positions": 100, "identity": "21.12%" }, { "cls_id": "homologset.agr.FB:FBgn0001216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63017-1", "uniprot_id": "HSP7C_MOUSE", "id": "P63017-1", "name": "Heat shock cognate 71 kDa protein", "aln": "--MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGG---FPG---GGAPPSGGASSGPTIEEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63018-1", "uniprot_id": "HSP7C_RAT", "id": "P63018-1", "name": "Heat shock cognate 71 kDa protein", "aln": "--MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGG---FPG---GGAPPSGGASSGPTIEEVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11142-1", "uniprot_id": "HSP7C_HUMAN", "id": "P11142-1", "name": "Heat shock cognate 71 kDa protein", "aln": "--MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGG---FPG---GGAPPSGGASSGPTIEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RCB1-1", "uniprot_id": "M0RCB1_RAT", "id": "M0RCB1-1", "name": "", "aln": "--MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPDEVSSMVLTKMKEIAEAYLGKTVT-----VPAYFNDSQRQAAKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVRAERNVLIFDLGGGTFDVSILTTEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ------------------------KPTLGSSQSPTT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q90473-1", "uniprot_id": "HSP7C_DANRE", "id": "Q90473-1", "name": "Heat shock cognate 71 kDa protein", "aln": "--MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVLDANRLNGRQFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYSNDSQRQATKDAGTISGLNVLVIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGSFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVEDEKLKGKISDEDKQKILDKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPEG---MPGGFPGAGAAPGGGSSGPTIEEVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61696-1", "uniprot_id": "HS71A_MOUSE", "id": "Q61696-1", "name": "Heat shock 70 kDa protein 1A", "aln": "--MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPG----------AGGFGAQAP-KGASGSGPTIEEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17879-1", "uniprot_id": "HS71B_MOUSE", "id": "P17879-1", "name": "Heat shock 70 kDa protein 1B", "aln": "--MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPG----------AGGFGAQAPPKGASGSGPTIEEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DMW0-1", "uniprot_id": "HS71A_RAT", "id": "P0DMW0-1", "name": "Heat shock 70 kDa protein 1A", "aln": "--MAKKTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVVNDGDKPKVQVNYKGENRSFYPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRERVAAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDSNTLAEKEEFVHKREELERVCNPIISGLYQGAGAPG----------AGGFGAQAP-KGGSGSGPTIEEVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DMV8-1", "uniprot_id": "HS71A_HUMAN", "id": "P0DMV8-1", "name": "Heat shock 70 kDa protein 1A", "aln": "--MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPG----------PGGFGAQGP-KGGSGSGPTIEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DMV9-1", "uniprot_id": "HS71B_HUMAN", "id": "P0DMV9-1", "name": "Heat shock 70 kDa protein 1B", "aln": "--MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPG----------PGGFGAQGP-KGGSGSGPTIEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16627-1", "uniprot_id": "HS71L_MOUSE", "id": "P16627-1", "name": "Heat shock 70 kDa protein 1-like", "aln": "MAANKGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVMVSYKGEKKAFYPEEISSMVLTKMKETAEAFLGHNVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGSHGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEGQREKIAAKNALESYAFNMKSAVGDEGLKDKISESDKKKILDKCNEVLSWLEANQLAEKDEFDHKRKELENMCNPIITKLYQ-SGCTG----------PTCTPGYTP--GRAATGPTIEEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29843-1", "uniprot_id": "HSP7A_DROME", "id": "P29843-1", "name": "Heat shock 70 kDa protein cognate 1", "aln": "--MPKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFDLGGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLAERQEFEHKQQELERICSPIITRLYQGAGMAP----------PPTAGGSNP-GATGGSGPTIEEVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "--MSK--AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "--MSK--AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "--MSK--AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "--MSR--AVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:***********. * :.:*:*************:*.**::***********.*:** **::**:** **.*.* * * * :** :. .:* : *.:*** : * *:::***:* **:* ** :** *. **** *******:****.*:*:*** ***************: *: *********:****:*: ::*:****:*************.*:*..: **:** ***: *:*::******.*****:****:*:.:*****:**:*****:******** .****.*::** * * *:*:**.::.::***********:*:*: *:***:: *:******************* **:* .********:*****:*****:** ** **:*****::: *:**:**********:****: *:*** **:*:*:.**********::****:*:***:**:* :*.*** *:************::*::** :** :: *: : ::: :** *** .: :: :: : :. * : ..: : **: . * :*: .: :**: :..**:: :* .** ", "identical_positions": 361, "similar_positions": 154, "identity": "55.2%" }, { "cls_id": "homologset.agr.FB:FBgn0001217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "-----MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKG--KEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGD-ESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQ--AGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "-----MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKG--KEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGD-ESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQ--AGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "-----MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKS--QKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGD-QSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYG--AAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "-----MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKG--RAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGD-QSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYG--AGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54652-1", "uniprot_id": "HSP72_HUMAN", "id": "P54652-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "--MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGD-KSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQGGPGGGSGG------------------GGSGASGGPTIEEVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11146-1", "uniprot_id": "HSP7B_DROME", "id": "P11146-1", "name": "Heat shock 70 kDa protein cognate 2", "aln": "---MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGV-GSSQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPS-GVLSETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMG------------------KGS----HPTVEEVDG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11484-1", "uniprot_id": "SSB1_YEAST", "id": "P11484-1", "name": "Ribosome-associated molecular chaperone SSB1", "aln": "MAEGVFQGAIGIDLGTTYSCVATYESS-VEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGK-SEKERHVLIFDLGGGTFDVSLLHIAGG-VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLLLDVAPLSLGVGMQGDMFGIVVPRNTTVPTIKRRTFTTCADNQTTVQFPVYQGERVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDALAALQIEDPS-ADELRKAEVGLKRVVTKAMSSR---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40150-1", "uniprot_id": "SSB2_YEAST", "id": "P40150-1", "name": "Ribosome-associated molecular chaperone SSB2", "aln": "MAEGVFQGAIGIDLGTTYSCVATYESS-VEIIANEQGNRVTPSFVAFTPQERLIGDAAKNQAALNPRNTVFDAKRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKIGKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGK-SEKERHVLIFDLGGGTFDVSLLHIAGG-VYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRRLRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKISKSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLLLDVAPLSLGVGMQGDIFGIVVPRNTTVPTIKRRTFTTVSDNQTTVQFPVYQGERVNCKENTLLGEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQAEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDALAALQIEDPS-ADELRKAEVGLKRVVTKAMSSR---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***********. : . *:****:****.***:*.*. ******.****.*:*. **:*********.*:* : * * :**:::. *:* ::*:: * * * *::**:*:* **:* ** :* *..**:********:*********:*:*:*************:****. *: **************:* * * :: **:*:*:*****:***..::..: ***:* *: : *::******.*****:*** :::::*:*:*.:* ** :.::*****:* **:.*::***:.* *:*:.* :.::***********:***: * *.**: : ***************.*** * * :****:**:*****: *.:: :: **: :* : . *:* :*** * . *::***. *:*.*** *:*..** * * * ::. *:::::***:*.* ::.***..:***:* ****. :*::*: :**.:: *: .: ::: **: .::: : : . . : .. *: . : :* : : . ::. ", "identical_positions": 284, "similar_positions": 176, "identity": "42.9%" }, { "cls_id": "homologset.agr.FB:FBgn0001218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20029-1", "uniprot_id": "BIP_MOUSE", "id": "P20029-1", "name": "Endoplasmic reticulum chaperone BiP", "aln": "-----------MMKFTVVAAALLLLGAVRAE---------EEDKKE-DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQD-ADIEDFKAKKKELEEIVQPIISKLYGSGG--PPPTGEEDTS-------EKDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06761-1", "uniprot_id": "BIP_RAT", "id": "P06761-1", "name": "Endoplasmic reticulum chaperone BiP", "aln": "------------MKFTVVAAALLLLCAVRAE---------EEDKKE-DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQD-ADIEDFKAKKKELEEIVQPIISKLYGSGG--PPPTGEEDTS-------EKDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11021-1", "uniprot_id": "BIP_HUMAN", "id": "P11021-1", "name": "Endoplasmic reticulum chaperone BiP", "aln": "------------MKLSLVAAMLLLLSAARAE---------EEDKKE-DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQD-ADIEDFKAKKKELEEIVQPIISKLYGSAG--PPPTGEEDTA-------EKDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29844-1", "uniprot_id": "BIP_DROME", "id": "P29844-1", "name": "Endoplasmic reticulum chaperone BiP", "aln": "------------MKLCILLAVVAFVGLSLGE---------EKKEKDKELGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQG-AKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPD-ADPEEYKKQKKDLEAIVQPVIAKLYQGAGGAPPPEGGDDAD-------LKDEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16474-1", "uniprot_id": "BIP_YEAST", "id": "P16474-1", "name": "Endoplasmic reticulum chaperone BiP", "aln": "MFFNRLSAGKLLVPLSVVLYALFVVILPLQNSFHSSNVLVRGADDVENYGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFTDD-ERLIGDAAKNQVAANPQNTIFDIKRLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGE-KKVFTPEEISGMILGKMKQIAEDYLGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQIIVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSDNNKALAKLKREAEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLKPVEKVLQDSGLEKKDVDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAVQAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPTVMIKVYEGERAMSKDNNLLGKFELTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKFASEDASIKAKVESRNKLENYAHSLKNQVNG--DLGEKLEEEDKETLLDAANDVLEWLDDNFETAIAEDFDEKFESLSKVAYPITSKLYGGADGSGAADYDDEDEDDDGDYFEHDEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : .: : . .. : ***:***********.* ***:.**:**:************* : ***********:::**:**:** ***** :.* .**:***.:**:**:*. ** :.*. *.*:*****.*:* ***: ** ***.*************************.****:*:**:************** : *::::*:************:*:****** **.*********** ::: ::** :*** * *: .:*:*: **:**.********.. ..****:** :* *:*************:***:.*:***:***:*:.::*.*:.:************:***::.:*.**:.*:*********************::.. :***** .**:****.***** ** ***.:******:**** *** ** *:******.::***:***.*:**********:*****:* :*.****:*:* *****:.:.*.****:.*** *:*:**:.:*****.** .:* ::::**:**.**:*****:.. .** **. ::*:.: .* :: ::**:.: : * *::. : :.*. :. *: :*** ... .. :: :***", "identical_positions": 390, "similar_positions": 182, "identity": "56.85%" }, { "cls_id": "homologset.agr.FB:FBgn0001220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48721-1", "uniprot_id": "HSPA9_RAT", "id": "P48721-1", "name": "Stress-70 protein, mitochondrial", "aln": "MISASRAAAARLVGTTASRSPAAARHQDGWNGLSHEAFRFVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTPDGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDTKNVPFKIVRASNGDAWVEAHG-KLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDASGPKHLNMKLTRAQFEGIVTDLIKRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARK---DSETGENIRQAASSLQQASLKLFEMAYKKMASERE---GSGSSSTGEQK----EDQKEEKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38647-1", "uniprot_id": "HSPA9_MOUSE", "id": "P38647-1", "name": "Stress-70 protein, mitochondrial", "aln": "MISASRAAAARLVGTAASRSPAAARPQDGWNGLSHEAFRFVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDTKNVPFKIVRASNGDAWVEAHG-KLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDASGPKHLNMKLTRAQFEGIVTDLIKRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRALLAGK---DSETGENIRQAASSLQQASLKLFEMAYKKMASERE---GSGSSGTGEQK----EDQKEEKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38646-1", "uniprot_id": "HSPA9_HUMAN", "id": "P38646-1", "name": "Stress-70 protein, mitochondrial", "aln": "MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHG-KLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARK---DSETGENIRQAASSLQQASLKLFEMAYKKMASERE---GSGSSGTGEQK----EDQKEEKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29845-1", "uniprot_id": "HSP7E_DROME", "id": "P29845-1", "name": "Heat shock 70 kDa protein cognate 5", "aln": "MLRVP-KFLPRLARQAGVVPSHMSGASSMFRNLPGASNGISSQLRYKSGEVKGAVIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVSSTDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLLANK---ETADLEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSGEAKKEEKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39987-1", "uniprot_id": "HSP7E_YEAST", "id": "P39987-1", "name": "Heat shock protein SSC3, mitochondrial", "aln": "----------MLPSWKAFKAHNI--------------LRILTR--FQSTKIPDAVIGIDLGTTNSAVAIMEGKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVINSENTLFATKRLIGRRFEDAEVQRDINQVPFKIVKHSNGDAWVEARN-RTYSPAQIGGFILNKMKETAEAYLAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDKSEPKVIAVFDLGGGTFDISILDIDNGIFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSNDRMAVQRIREAAEKAKIELSSTLSTEINLPFITADAAGPKHIRMPFSRVQLENITAPLIDRTVDPVKKALKDARITASDISDVLLVGGMSRMPKVADTVKKLFGKDASKAVNPDEAVALGAAIQAAVLSGEVTDVLLLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQGERELVKDNKLIGNFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLASHKDSSITVAGASGLSDTEIDRMVNEAERYKNQDRARRNAIETANKADQLANDTENSIKEFEGKLDKTDSQRLKDQISSLRELVSRSQAGDEVNDDDVGTKIDNLRTSSMKLFEQLYKN-SDNPE-------TKNGR----------ENK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CS90-1", "uniprot_id": "HSP77_YEAST", "id": "P0CS90-1", "name": "Import motor subunit, mitochondrial", "aln": "----------MLAAKNILNRSSLS-----------SSFRIATR--LQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARG-QTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNN-------NNNGNNA-----ESGETKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: * : .:*:*********.:*:**** .:::*****:***** **** :****** *****:* *. **::*********::*.**::* .::.:*:*: *******.: . : ***:***.*:* ******* ** ..****:********:*********** *******:***********::*:: *::**:************:*::*:********** ******* ::. :: .** ::*:*: :*.:*:**::******* ****: .*:****::* *::**:*:.: ::* ::* :. *: **: * :**:.** :: *:*.:*:*****:***** .**:.***: .*::********:***:*..**:*:************************:** **:***.****:****: ***.**::* *****:. ****:*.*** ******:*.*****.*****:**::***:* .: ::..*.: .:.***. :*:.*::.**.: *. ::: :* .* .: : :***..::**:.:: :.::::.:*:.:: *:: : ::: ..*: :*:**** **: : : : . .. * * ", "identical_positions": 343, "similar_positions": 200, "identity": "49.71%" }, { "cls_id": "homologset.agr.FB:FBgn0001222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MK39-1", "uniprot_id": "A0A096MK39_RAT", "id": "A0A096MK39-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MQEAPAALPTEPG-PSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGCEQLLERVRRKVP-----------------------------------------------------ALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTG-PSSTGAKRKLSLMLD--------------------------------EGSACSASAKF-NACPVSGALLQDPYFIQSPL-PETT-VGLSPHRA----------------------RGPIISDIPEDCPSPEGHRLSPSSAGRRVKG--LALLKEEP-----------ASPGGDG-EAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGS----FSPEGPRSIQQPEPRGPREVPDR---------GTL--GLDRGNRSPESLLPPVLLRPPPETVEP-------MDALG---------------PSLHGREWTLMDLDMELSLMQPLAPERAEAELTVKDLTSSGVGK---DHTLGTPLMLDVQADLEG----AALSVPGALTLYNA----TES-NASYLDPGASPSSP----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0L1-1", "uniprot_id": "HSF4_MOUSE", "id": "Q9R0L1-1", "name": "Heat shock factor protein 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MQEAPAALPTEPG-PSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRRKVP-----------------------------------------------------ALRGDDSRWRPEDLSRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTG-PSSTGAKRKLSLMLD--------------------------------EGSACSASAKF-NACPVSGALLQDPYFIQSPL-PETT-LGLSPHRA----------------------RGPIISDIPEDSPSPEGHRLSPSGGCRRVKG--LALLKEEP-----------ASPGGDG-EAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGS----YSPEGPRSVQQPEPRGPREVPDR---------GTL--GLDRGNRSPESLLPPMLLRPAPETLEPVA---P-VDVLG---------------PSLHGREWTLMDLDMELSLMQPLAPETDEAELTVKELNSSGVGK---DHTLGTPLMLDVQADLEG----AALSVPGALTLYNV----TES-NASYLDPGASPSSP----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULV5-1", "uniprot_id": "HSF4_HUMAN", "id": "Q9ULV5-1", "name": "Heat shock factor protein 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MQEAPAALPTEPG-PSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRRKVP-----------------------------------------------------ALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQQHRVIGKLIQCLFGPLQAG-PSNAGGKRKLSLMLD--------------------------------EGSSCPTPAKF-NTCPLPGALLQDPYFIQSPL-PETN-LGLSPHRA----------------------RGPIISDIPEDSPSPEGTRLSPSSDGRREKG--LALLKEEP-----------ASPGGDG-EAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGS----FSPEGPRNAQQPEPGDPREIPDR---------GPL--GLESGDRSPESLLPPMLLQPPQESVEPAG---P-LDVLG---------------PSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGK---DPTLGAPLLLDVQAALGG----PALGLPGALTIYST----PESRTASYLGPEASPSP-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5CZP2-1", "uniprot_id": "HSF4_DANRE", "id": "Q5CZP2-1", "name": "Heat shock factor protein 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MQENPGSIGVDGGYASNVPAFLTKLWTLVEDPETNHLICWSATGTSFHVFDQGRFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVNIEQSGLVKPERDD-TEFQHLYFLQGHEHLLEHIKRKVS-----------------------------------------------------IVKSEETKVRQEDLSKLLYEVQVLRSQQENMEMQMQDMKQQNDVLWREVVSLRQNHTQQQKVMNKLIQFLFSQMQSNSPSTVGMKRKLPLMLD--------------------------------DGCSTPPASKF-SHN-HSMESLQESFYIQSPS-TESASCSTSSVMT----------------------GGPIISDVT-EIPQSSSMALQMQAEESREKC--LMLIKEEP-----------VSPGVQGRAEGVPLG--SCEVCA-EPPVLPVAMVQSVLEGRG------SNLGERRAKRPMLERP-EIPD---------------GVENVDMSLEDLQ--LLLRSHQQSMENNA---AAMDQFT---------------FSLPLNEWNFAEMDPNL------------------------------------------KSELAN----ALIPAAVSQYMFQG----QEG----ELYPTAGYEEQ----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38532-1", "uniprot_id": "HSF1_MOUSE", "id": "P38532-1", "name": "Heat shock factor protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLAVG--PGAAG-PSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKVTSV--------------------------------------------------STLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSN--RILGVKRKIPLMLS--------------------------------DSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTS----------------------SGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTG-----AQAPALPTPSTPEKCLSVACLDK---------NELSDHLDAMDSNLDNLQ--TMLTSHGFSVDTSA---L-LDLFS---------------PSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAF1-1", "uniprot_id": "F1MAF1_RAT", "id": "F1MAF1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLAVG--PGAAG-PSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKVTSV--------------------------------------------------STLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSN--RILGVKRKIPLMLS--------------------------------DSSSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTS----------------------SGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKEEPPSPPHSPRVLEASPGRPASMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTG-----AQAPAPPAPSTPEKCLSVACLDK---------NELSDHLDAMDSNLDNLQ--TMLTSHGFSVDTSA---L-LDLFS---------------PSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNADSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00613-1", "uniprot_id": "HSF1_HUMAN", "id": "Q00613-1", "name": "Heat shock factor protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLPVG--PGAAG-PSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKVTSV--------------------------------------------------STLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSN--RILGVKRKIPLMLN--------------------------------DSGSAHSMPKYSRQFSLEHVHGSGPYSAPSPAYSSSSLYAPDAVAS----------------------SGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAP-ASVTALTDARGHTDTEGRPPSPPPTSTPEKCLSVACLDK---------NELSDHLDAMDSNLDNLQ--TMLSSHGFSVDTSA---L-LDLFS---------------PSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22813-1", "uniprot_id": "HSF_DROME", "id": "P22813-1", "name": "Heat shock factor protein", "aln": "------------------------------------------------------------------------------------------------------------------------------MSRSRSSAKAVQFKHESEEEEEDEEEQLPSRRMHSYGDAAAIGSGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGLR-FDRDE-IEFSHPFFKRNSPFLLDQIKRKISN---------------------------------------------------NKNGDDKGVLKPEAMSKILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPS-RNMSGVKRHVQLMINNTPEIDRARTTSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYSNQSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEAPDSHVQEVPNSPPYYEEQNVLTTPMVREQEQQKRQQLKENNKLRRQAGDVILDAGDILVDSSSPKAQRTSIQHSTQPDVMVQPMIIKSEPENSSGLMDL---------MTPANDLYSVNFISEDMPTDIFEDALLPDGVEEA---AKLDQQQKFGQSTVSSGKFASNFDVPTNSTLLDANQASTSKAAAKAQASEEEGMAVAKYSGAENGNNRDTNNSQLLRMASVDELHGHLESMQDELETLKDLLRGDGVAIDQNMLMGLFNDSDLMDNYGLSFPNDSISSEKKAPSGSELISYQPMYDLSDILDTDDGNNDQEASRRQMQTQSSVLNTPRHEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38533-1", "uniprot_id": "HSF2_MOUSE", "id": "P38533-1", "name": "Heat shock factor protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIESGIIKQERDGP-VEFQHPYFKQGQDDLLENIKRKVS-----------------------------------------------------SSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNN--QLVSLKRKRPLLLN-------------------------------------TNGAPKKNLYQHIVKEPTDNHHHKVPHSRTEGLKSRERISD-----------------------DIIIYDVTDDNVDEENIPVIPETNEDVVVDSS--NQYPDIVIVEDDNEDEYAPVIQSGEQSEPAREPLRVGSAGSSSPLMSSAVQLNGSSSLTS-------EDPVTMMDSILNDNINLLGK---------VELLDYLDSIDCSLEDFQ--AMLSGRQFSIDPDL---L-VDLFT---------------SSVQMNPTDNIKYTKSENKGLEATKSSVVQHVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNSASAIEQGSTTASSEVVPSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L2J2-1", "uniprot_id": "A0ABK0L2J2_RAT", "id": "A0ABK0L2J2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIESGIVKQERDGP-VEFQHPHFKQGQDDLLENIKRKVS-----------------------------------------------------SSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNN--QLVSLKRKRPLLLN-------------------------------------TNGAPKKNLFQHIVKEPTDNHHHKVPHSRTEGLKSRERISD-----------------------DIIIYDVTEDNVDEENIPVIPETNEDVVVDPS--SQYPDIVIVEDDNEDEYAPVIQSGEQSEPA----RVGSASSSSPLMSSAVQLNGSSNLTS-------EDPVTMMDSILNDNINLLGK---------VELLDYLDSIDCSLEDFQ--AMLSGRQFSIDPDL---L-VDLFT---------------SSVQMNPTDYINNTKSENKGLEATKNSVVQQVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASAVEQGTTTASSEVVPSVDKPIEVDELLDSNLDQEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03933-1", "uniprot_id": "HSF2_HUMAN", "id": "Q03933-1", "name": "Heat shock factor protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGP-VEFQHPYFKQGQDDLLENIKRKVS-----------------------------------------------------SSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNN--QLVSLKRKRPLLLN-------------------------------------TNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRERISD-----------------------DIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGSS-PLMSSAVQLNGSSSLTS-------EDPVTMMDSILNDNINLLGK---------VELLDYLDSIDCSLEDFQ--AMLSGRQFSIDPDL---L-VDLFT---------------SSVQMNPTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QH55-1", "uniprot_id": "A0A8M9QH55_DANRE", "id": "A0A8M9QH55-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNVPAFVSKLWTLVEAQATNHLICWSQDGCSFLVQDEQRFSKEVLPLYFKHSNMTSFVRQLNMYGFHKVMHVDSGLPKAESQINCVEFQHEDFQRDQPHLLGLIRRKVS--------------------------------------------------------VSRGAEEGGQMSQVIVQVRHFRGCQDSSDLKLTALCRDNESLWRELDTLRQNYQQQHKIIRKIIKFIINSVQLN--GIKGCKRRLPMIDN----------------------------------SGEFHSAPKYARSFGVNSTLTTSCLQENPSLQELDVSSADVYSN-----------------------GMIISDITDLLDPTPELNRGCMTECLPEILP------------------------TFSPPASPSMPSMDLALSFLDDPVVLESEETAQ-------------------------------ER---------NDVCDPLALIDSSLEAIR--SCSPPSPPDLDNFSKILS---------------------PGCHISAAKVTESKQESQNEENTVTHQRSLQQHTDLQQEHCDDDDGEFLDILPSLLQLAQEASSLSFSNTILPLEIPFVI-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10961-1", "uniprot_id": "HSF_YEAST", "id": "P10961-1", "name": "Heat shock transcription factor", "aln": "MNNAANTGTTNESNVSDAPRIEPLPSLNDDDIEKILQPNDIFTTDRTDASTTSSTAIEDIINPSLDPQSAASPVPSSSFFHDSRKPSTSTHLVRRGTPLGIYQTNLYGHNSRENTNPNSTLLSSKLLAHPPVPYGQNPDLLQHAVYRAQPSSGTTNAQPRQTTRRYQSHKSRPAFVNKLWSMLNDDSNTKLIQWAEDGKSFIVTNREEFVHQILPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSIQSSSDDK-WQFENENFIRGREDLLEKIIRQKGSSNNHNSPSGNGNPANGSNIPLDNAAGSNNSNNNISSSNSFFNNGHLLQGKTLRLMNEANLGDKNDVTAILGELEQIKYNQIAISKDLLRINKDNELLWQENMMARERHRTQQQALEKMFRFLTSIVPHLDPKMIMDGLGDPKVNNEKLNSANNIGLNRDNTG-------TIDELKSNDSFINDDRNSFTNATTNARNNMSPNNDDNSIDTASTNTTNRKKNIDEN-----------------IKNNNDIINDIIFNTNLANNLSNYNSNNNAGSPIRPYKQRYLLKNRANSSTSSENPSLTPFDIESNNDRKISEIPFDDEEEEETDFRPFTSRDPNNQTSENTFDPNRFTMLSDDDLKKDSHTNDNKHNESDLFWDNVHRNIDEQDARLQNLENMVHILSPGYPNKSFNNKTSSTNTNSNMESAVNVNSPGFNLQDYLTGESNSPNSVHSVPSNGSGSTPLPMPNDNDTEHASTSVNQGENGSGLTPFLTVDDHTLNDNNTSEGSTRVSPDIKFSATENTKVSDNLPSFNDHSYSTQADTAPENAKKRFVEEIPEPAIVEIQDPTEYNDHRLPKRAKK-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ***: *** :: . :* *: * ** : :. .* :::** :**.*::**:*******::*: :... :*.: * :. ** : *: . : :: . . .: * . : : :*: **:* * : *:: : *:.: : : : . . . : .: : : : : . . ", "identical_positions": 40, "similar_positions": 69, "identity": "4.53%" }, { "cls_id": "homologset.agr.FB:FBgn0001223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35878-1", "uniprot_id": "HSPB2_RAT", "id": "O35878-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFAN--PSRLGEQRFGEGLLPE--------EILTP--TLYHGYYVRPRAARAGEGGR------------A-GASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDN-LLEVSARHPQRLDRHG-FVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR------------------------------------GGRHLDTEVNEVYISLLPAPPDPEEEEEVARVEP--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PR8-1", "uniprot_id": "HSPB2_MOUSE", "id": "Q99PR8-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFAN--PSRLGEQRFGEGLLPE--------EILTP--TLYHGYYVRPRAARAGEGAR------------A-GASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDN-LLEVSARHPQRLDRHG-FVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR------------------------------------GGRHLDTEVNEVYISLLPAPPDPEEEEEIARVEP--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16082-1", "uniprot_id": "HSPB2_HUMAN", "id": "Q16082-1", "name": "Heat shock protein beta-2", "aln": "MSGRSVPHAHPATAEYEFAN--PSRLGEQRFGEGLLPE--------EILTP--TLYHGYYVRPRAAPAGEGSR------------A-GASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDN-LLEVSARHPQRLDRHG-FVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR------------------------------------GGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24623-1", "uniprot_id": "CRYAA_RAT", "id": "P24623-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY---PSRLFDQFFGEGLFEY--------DLLPFLSSTISPYYR-QSLFR--TVLD------------S-GISELMTHMWFVMHQPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLED-FVEIHGKHNERQDDHG-YISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPK------------------------------------VQSGLDAGHSER--AIPVSREEKPSSAPSS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24622-1", "uniprot_id": "CRYAA_MOUSE", "id": "P24622-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY---PSRLFDQFFGEGLFEY--------DLLPFLSSTISPYYR-QSLFR--TVLD------------S-GISELMTHMWFVMHQPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLED-FVEIHGKHNERQDDHG-YISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPK------------------------------------VQSGLDAGHSER--AIPVSREEKPSSAPSS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02489-1", "uniprot_id": "CRYAA_HUMAN", "id": "P02489-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRTLGPFY---PSRLFDQFFGEGLFEY--------DLLPFLSSTISPYYR-QSLFR--TVLD------------S-GISE-----------------------VRSDRDKFVIFLDVKHFSPEDLTVKVQDD-FVEIHGKHNERQDDHG-YISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPK------------------------------------IQTGLDATHAER--AIPVSREEKPTSAPSS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02511-1", "uniprot_id": "CRYAB_HUMAN", "id": "P02511-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS--PSRLFDQFFGEHLLES--------DLFPTSTSLSPFYLRPPSFLRAPSWFD------------T-GLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGD-VIEVHGKHEERQDEHG-FISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPR------------------------------------KQV----SGPER--TIPITREEKPAVTAAPKK----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23927-1", "uniprot_id": "CRYAB_MOUSE", "id": "P23927-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS--PSRLFDQFFGEHLLES--------DLFSTATSLSPFYLRPPSFLRAPSWID------------T-GLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGD-VIEVHGKHEERQDEHG-FISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPR------------------------------------KQV----SGPER--TIPITREEKPAVAAAPKK----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23928-1", "uniprot_id": "CRYAB_RAT", "id": "P23928-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS--PSRLFDQFFGEHLLES--------DLFSTATSLSPFYLRPPSFLRAPSWID------------T-GLSE-----------------------MRMEKDRFSVNLDVKHFSPEELKVKVLGD-VIEVHGKHEERQDEHG-FISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPR------------------------------------KQA----SGPER--TIPITREEKPAVTAAPKK----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q8E3-1", "uniprot_id": "A0A8M9Q8E3_DANRE", "id": "A0A8M9Q8E3-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAINPP-FRRILFPIFF--PRRQ----FGEHITEA--------DVISS------LYSQRSSFLRSPSWME------------S-GVSE-----------------------VKMEKDQFSLSLDVKHFAPEELSVKIIGD-FIEIHAKHEDRQDGHG-FVSREFLRKYRVPVGVDPASITSSLSSDGVLTVTGPL------------------------------------KLS----DGPERTIAIPVTRDDKTTVAGPQKRKKLKQVWNKWRGAS--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RK31-1", "uniprot_id": "A0A8M1RK31_DANRE", "id": "A0A8M1RK31-1", "name": "", "aln": "MADAKSPQYCQDVSWIPLSCRWPSVIFNQHFGMPPLLEPRDLSWMEDIFRRLGTSSWPGYVRSGFLAPLLQASGPAVFSKPHRELSG-----------------------GVSEVAAETCRWKISLDVNHFAPAEISVKIQHG-FLEIAGKHEERQDGHG-FIARSFTRKYNLPGGIEVENLQTSLSADGILTVEAPFPSIPLPADVIIPIQVESGAQTIAGKQQDGDKPQDDIKPESFDGKTPESSVSAGHPDAGKVTERDQQTVSDVDPSREAQPQSIAEAASGFSVSGREQVGEPLAGREKDKEGRFQETVEGIQRDGESADKPLAPETPDTITSEQAEVIQLGDLEGEEGCTGPAVMREEQSTFGQSQELINPQLVLQKKIDAGKM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02515-1", "uniprot_id": "HSP22_DROME", "id": "P02515-1", "name": "Heat shock protein 22", "aln": "-MRSLPMFWRMAEEMARMPR--LSSPFHAFFHEPPVWS---------VALPRNWQQIARWQEQEFAP----------------------------------------------PATVNKDGYKLTLDVKDYS--ELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTISVPN-------------------------------------PPGVQETLKEREVTIEQTGEPAKKSAEEPNDKAASQ-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : ***..:: ::.*: .: : .: :: :* : :* * * : :* . : : :** **:*.. * * : . ", "identical_positions": 17, "similar_positions": 33, "identity": "4.36%" }, { "cls_id": "homologset.agr.FB:FBgn0001224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35878-1", "uniprot_id": "HSPB2_RAT", "id": "O35878-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFAN--PSRLGEQRFGEGLLPE--------EILT---PTLYHGYYVRPRAARAGEGGRAGASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHL---------------------------------------------------DTEVNEVYISLLPAPPDPEEEEEVARVEP-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PR8-1", "uniprot_id": "HSPB2_MOUSE", "id": "Q99PR8-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFAN--PSRLGEQRFGEGLLPE--------EILT---PTLYHGYYVRPRAARAGEGARAGASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHL---------------------------------------------------DTEVNEVYISLLPAPPDPEEEEEIARVEP-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02511-1", "uniprot_id": "CRYAB_HUMAN", "id": "P02511-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS--PSRLFDQFFGEHLLES--------DLFP-TSTSLSPFYLRPPSFLRAPSWFDTGLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQ-------------------------------------------------------VSGPERTIPITREEKPAVTAAPKK---------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23927-1", "uniprot_id": "CRYAB_MOUSE", "id": "P23927-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS--PSRLFDQFFGEHLLES--------DLFS-TATSLSPFYLRPPSFLRAPSWIDTGLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQ-------------------------------------------------------VSGPERTIPITREEKPAVAAAPKK---------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23928-1", "uniprot_id": "CRYAB_RAT", "id": "P23928-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS--PSRLFDQFFGEHLLES--------DLFS-TATSLSPFYLRPPSFLRAPSWIDTGLSE-----------------------MRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQ-------------------------------------------------------ASGPERTIPITREEKPAVTAAPKK---------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24623-1", "uniprot_id": "CRYAA_RAT", "id": "P24623-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY---PSRLFDQFFGEGLFEY--------DLLPFLSSTISPYYR--QSLFRT--VLDSGISELMTHMWFVMHQPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGL---------------------------------------------------DAGHSERAIPVSREEKP--SSAPSS---------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24622-1", "uniprot_id": "CRYAA_MOUSE", "id": "P24622-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY---PSRLFDQFFGEGLFEY--------DLLPFLSSTISPYYR--QSLFRT--VLDSGISELMTHMWFVMHQPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGL---------------------------------------------------DAGHSERAIPVSREEKP--SSAPSS---------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02489-1", "uniprot_id": "CRYAA_HUMAN", "id": "P02489-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRTLGPFY---PSRLFDQFFGEGLFEY--------DLLPFLSSTISPYYR--QSLFRT--VLDSGISE-----------------------VRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGL---------------------------------------------------DATHAERAIPVSREEKP--TSAPSS---------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RK31-1", "uniprot_id": "A0A8M1RK31_DANRE", "id": "A0A8M1RK31-1", "name": "", "aln": "MADAKSPQYCQDVSWIPLSCRWPSVIFNQHFGMPPLLEPRDLSWMEDIFRRLGTSSWPGYVRSGFLAPLLQASGPAVFSKPHRELSG-----------GVSEVAAETCRWKISLDVNHFAPAEISVKIQHGFLEIAGKHEERQDGHGFIARSFTRKYNLPGGIEVENLQTSLSADGILTVEAPFPSIPLPADVIIPIQVESGAQTIAGKQQDGDKPQDDIKPESFDGKTPESSVSAGHPDAGKVTERDQQTVSDVDPSREAQPQSIAEAASGFSVSGREQVGEPLAGREKDKEGRFQETVEGIQRDGESADKPLAPETPDTITSEQAEVIQLGDLEGEEGCTGPAVMREEQSTFGQSQELINPQLVLQKKIDAGKM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02516-1", "uniprot_id": "HSP23_DROME", "id": "P02516-1", "name": "Heat shock protein 23", "aln": "-MANIPLLLSLADDLGRMS---MVPFYEPYYCQRQRNP----------YLALVGPMEQQLRQLEKQVGASSGSSGAVSK-------------------------IGKDGFQVCMDVSHFKPSELVVKVQDNSVLVEGNHEEREDDHGFITRHFVRRYALPPGYEADKVASTLSSDGVLTIKVPKPPAIE--------------------------------------------------DKGNERIVQIQQVGPAHLNVKENPKEAVEQDNGNDK-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . . : :**.** * :: *: . : : ..* :* * **:::* * * * :* . : : :** **:*.. * ", "identical_positions": 22, "similar_positions": 30, "identity": "5.85%" }, { "cls_id": "homologset.agr.FB:FBgn0001225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35878-1", "uniprot_id": "HSPB2_RAT", "id": "O35878-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPT---LYHGYYVRPRAARAGEGGRAGASE------------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR------------------------------------------------------------------------------------GGRHLDTEVNEVYIS---------------------------------------------------------LLPAPPDPEEEEEVARVEP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PR8-1", "uniprot_id": "HSPB2_MOUSE", "id": "Q99PR8-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPT---LYHGYYVRPRAARAGEGARAGASE------------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR------------------------------------------------------------------------------------GGRHLDTEVNEVYIS---------------------------------------------------------LLPAPPDPEEEEEIARVEP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24623-1", "uniprot_id": "CRYAA_RAT", "id": "P24623-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY-PSRLFDQFFGEGLFEYDLLPFL-SSTISPYYR-QSLFR--TVLDSGISELMTHMW-FVMHQPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPK------------------------------------------------------------------------------------VQSGLDAGHSER--------------------------------------------------------------AIPVSREEKPSSAPSS------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24622-1", "uniprot_id": "CRYAA_MOUSE", "id": "P24622-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY-PSRLFDQFFGEGLFEYDLLPFL-SSTISPYYR-QSLFR--TVLDSGISELMTHMW-FVMHQPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPK------------------------------------------------------------------------------------VQSGLDAGHSER--------------------------------------------------------------AIPVSREEKPSSAPSS------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02489-1", "uniprot_id": "CRYAA_HUMAN", "id": "P02489-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFL-SSTISPYYR-QSLFR--TVLDSGISE------------------------VRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPK------------------------------------------------------------------------------------IQTGLDATHAER--------------------------------------------------------------AIPVSREEKPTSAPSS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02511-1", "uniprot_id": "CRYAB_HUMAN", "id": "P02511-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTS-TSLSPFYLRPPSFLRAPSWFDTGLSE------------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPR------------------------------------------------------------------------------------KQV----SGPER--------------------------------------------------------------TIPITREEKPAVTAAPKK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23927-1", "uniprot_id": "CRYAB_MOUSE", "id": "P23927-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTA-TSLSPFYLRPPSFLRAPSWIDTGLSE------------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPR------------------------------------------------------------------------------------KQV----SGPER--------------------------------------------------------------TIPITREEKPAVAAAPKK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23928-1", "uniprot_id": "CRYAB_RAT", "id": "P23928-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTA-TSLSPFYLRPPSFLRAPSWIDTGLSE------------------------MRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPR------------------------------------------------------------------------------------KQA----SGPER--------------------------------------------------------------TIPITREEKPAVTAAPKK----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q8E3-1", "uniprot_id": "A0A8M9Q8E3_DANRE", "id": "A0A8M9Q8E3-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAINPP-FRRILFPIFFPRRQ----FGEHITEADVISS-------LYSQRSSFLRSPSWMESGVSE------------------------VKMEKDQFSLSLDVKHFAPEELSVKIIGDFIEIHAKHEDRQDGHGFVSREFLRKYRVPVGVDPASITSSLSSDGVLTVTGPL------------------------------------------------------------------------------------KLS----DGPERT------------------------------------------------------------IAIPVTRDDKTTVAGPQKRKKLKQVWNKWRGAS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RK31-1", "uniprot_id": "A0A8M1RK31_DANRE", "id": "A0A8M1RK31-1", "name": "", "aln": "--MADAKSPQYCQDVSWIPLSCRWPSVIFNQHFGMPPLLEPRDLSWMEDIFRRLGTSSWPGYVRSGFLAPLLQASGPAVFSKPHRELSGGVSEVAAETCRWKISLDVNHFAPAEISVKIQHGFLEIAGKHEERQDGHGFIARSFTRKYNLPGGIEVENLQTSLSADGILTVEAPFPSIPLPADVIIPIQVESGAQTIAGKQQDGDKPQDDIKPESFDGKTPESSVSAGHPDAGKVTERDQQTVSDVDPSREAQPQSIAEAASGFSVSGREQVGEPLAGREKDKEGRFQETVEGIQRDGESADKPLAPETPDTITSEQAEVIQLGDLEGEEGCTGPAVMREEQSTFGQSQELINPQLVLQKKIDAGKM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02517-1", "uniprot_id": "HSP26_DROME", "id": "P02517-1", "name": "Heat shock protein 26", "aln": "-MSLSTLLSLVDELQEPRSPIYELGLGLHPHSRYVLPLGTQQRRSINGCPCASPICPSSPAGQVLALRREMANRN-----------DIHWPATAHVGKDGFQVCMDVAQFKPSELNVKVVDDSILVEGKHEERQDDHGHIMRHFVRRYKVPDGYKAEQVVSQLSSDGVLTVSIPK-------------------------------------------------------------------------------------PQAVEDKSKER------------------------------------------------------------IIQIQQVGPAHLNVKANESEVKGKENGAPNGKDK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . : :** :* * ::.*: . : : .:* :* * **.: * * * * :* . . : ** **:*.. * * . ", "identical_positions": 22, "similar_positions": 29, "identity": "5.99%" }, { "cls_id": "homologset.agr.FB:FBgn0001227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35878-1", "uniprot_id": "HSPB2_RAT", "id": "O35878-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFAN-PSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAARAGEGGRAGASE---------------------------------------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLD--TEVNEVYISLLPAPPDPEEEEEVARVEP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PR8-1", "uniprot_id": "HSPB2_MOUSE", "id": "Q99PR8-1", "name": "Heat shock protein beta-2", "aln": "MSGRTVPHAHPATAEYEFAN-PSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAARAGEGARAGASE---------------------------------------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLD--TEVNEVYISLLPAPPDPEEEEEIARVEP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16082-1", "uniprot_id": "HSPB2_HUMAN", "id": "Q16082-1", "name": "Heat shock protein beta-2", "aln": "MSGRSVPHAHPATAEYEFAN-PSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAAPAGEGSRAGASE---------------------------------------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLD--TEVNEVYISLLPAPPDPEEEEEAAIVEP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23928-1", "uniprot_id": "CRYAB_RAT", "id": "P23928-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS-PSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSE---------------------------------------------------MRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQA------SGPER--TIPITREEKPAVTAAPKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23927-1", "uniprot_id": "CRYAB_MOUSE", "id": "P23927-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS-PSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSE---------------------------------------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV------SGPER--TIPITREEKPAVAAAPKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02511-1", "uniprot_id": "CRYAB_HUMAN", "id": "P02511-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAIHHPWIRRPFFPFHS-PSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSE---------------------------------------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV------SGPER--TIPITREEKPAVTAAPKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8E3-1", "uniprot_id": "A0A8M9Q8E3_DANRE", "id": "A0A8M9Q8E3-1", "name": "Alpha-crystallin B chain", "aln": "-MDIAINPP-FRRILFPIFF-PRRQ----FGEHITEADVISS------LYSQRSSFLRSPSWMESGVSE---------------------------------------------------VKMEKDQFSLSLDVKHFAPEELSVKIIGDFIEIHAKHEDRQDGHGFVSREFLRKYRVPVGVDPASITSSLSSDGVLTVTGPLKLS------DGPERTIAIPVTRDDKTTVAGPQKRKKLKQVWNKWRGAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24623-1", "uniprot_id": "CRYAA_RAT", "id": "P24623-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY--PSRLFDQFFGEGLFEYDLLPFLSSTISPYYR-QSLFR--TVLDSGISELMTHMWFVMH----------------------------QPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLD--AGHSER--AIPVSREEKPSSAPSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24622-1", "uniprot_id": "CRYAA_MOUSE", "id": "P24622-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRALGPFY--PSRLFDQFFGEGLFEYDLLPFLSSTISPYYR-QSLFR--TVLDSGISELMTHMWFVMH----------------------------QPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLD--AGHSER--AIPVSREEKPSSAPSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02489-1", "uniprot_id": "CRYAA_HUMAN", "id": "P02489-1", "name": "Alpha-crystallin A chain", "aln": "-MDVTIQHPWFKRTLGPFY--PSRLFDQFFGEGLFEYDLLPFLSSTISPYYR-QSLFR--TVLDSGISE---------------------------------------------------VRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLD--ATHAER--AIPVSREEKPTSAPSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05812-1", "uniprot_id": "HSP6A_DROME", "id": "P05812-1", "name": "Heat shock protein 67B1", "aln": "-MSLIPFILDLAEELHDFNRSLAMDIDDSAGFGLYPLEATSQLPQLSRGLGRGNAMMWVPIKGQSAASQHRHHPYNRVAGAKTACCNKSLVELEKELGDKGTSGASGSTSGQPAASKSAYSVVNRNGFQVSMNVKQFAANELTVKTIDNCIVVEGQHDEKEDGHGVISRHFIRKYILPKGYDPNEVHSTLSSDGILTVKAPPPLPVVKGSLERQERIVDIQQISQQQKDKDAQPPKPSEVEQQAAASATTSTLNPTAPTPTPSLSLTLAESNGNGQEETEMEMPAVSPPISNEAAAAAAVAVEAPSTAGTTSSANNGVAEPESESMEVALAKNEETANVDEPTPNPVISIEEEQKAEDANANEVPVASNNGNGAVAAAEDVEMPLAKKPEISTEDSKEEQAEKVDKVEKVEEKGGEELAAVDAAILLAKNQGENGATAAKTEELAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : : . :. *: ... * ::*.:*:.:::.*: : : : .:* :: * ** :**.* * * :* . * : .:** **:*.. .* * : : ", "identical_positions": 24, "similar_positions": 42, "identity": "5.38%" }, { "cls_id": "homologset.agr.FB:FBgn0001228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8W9-1", "uniprot_id": "G3V8W9_RAT", "id": "G3V8W9-1", "name": "", "aln": "MLARLVLGTSCRAVLGSVEPALGGLKSRWGSSQ--------------------HFCSTLSKDVTYRELKNLLNSKD--IMLIDVRNTWEILEHGKIPGSVNIPLDEVGEALQMNPREFKEKYGEEKPSKSDR-LVFSCLAGVRSKKAMDTAISLGFNSAQHYIGGWTEWVTYEISEKKQS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0B5-1", "uniprot_id": "TSTD3_MOUSE", "id": "Q9D0B5-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "MLARLVLGTSGRAALGSVEPALGGLKSIWRCSQ--------------------AFCSTP-KGVTYRELKSLLNSKD--IMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSKSDR-LVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFU3-1", "uniprot_id": "TSTD1_HUMAN", "id": "Q8NFU3-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "------------------------------MAG--------------------------APTVSLPELRSLLASGR--ARLFDVR-SREEAAAGTIPGALNIPVSELESALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREWLEKES-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LEJ3-1", "uniprot_id": "A0ABK0LEJ3_RAT", "id": "A0ABK0LEJ3-1", "name": "Rhodanese domain-containing protein", "aln": "MEVPENPWDVRVRCLQVPWGGLFVERGAWGVAAGLKQPGRGVQRQVSCPPALKSFFSFPVPTVSFSELRQLLASGR--ARLFDVR-SREEAAAGTIPGALNIPVSELEMALNMDPAAFQTSYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKEG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PY03-1", "uniprot_id": "E9PY03_MOUSE", "id": "E9PY03-1", "name": "", "aln": "--------MLRLAVLRHSH----TSAAAGTMAG--------------------------VPTVSFSELRSLVASGR--ARLFDVR-SPEEAAAGTIPGALNIPVSELEIALNMDPAAFQTLYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKQG-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A5G0-1", "uniprot_id": "B8A5G0_DANRE", "id": "B8A5G0-1", "name": "", "aln": "-------------------------MAS------------------------------SDNDISYSDLKSILAKGS--AVLVDVR-TNEEVARGTIPGSIHIPVGNIGQDLSLDAAEFQSKFGVGKPPLDCTELVFFCQLGRRGAAATEKAKSLGFKNARNYAGAYKEWSEKEGK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PUV1-1", "uniprot_id": "A0A8M1PUV1_DANRE", "id": "A0A8M1PUV1-1", "name": "", "aln": "MVSFQILRRLGVFALTKPVCHGRILSACGIKTSNIN---------------HSHGQPGAVSVVTYEQLKGMLANHS--VQLFDVR-NPDEFQAGRIPDSVNVPLGELEVSLKLPAEKFEEQFKVKAPQKADDNIVFHCRSGKRSLTALETAHRLGFSKARHYAGGYIDWEEREKN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22978-1", "uniprot_id": "CG445_DROME", "id": "P22978-1", "name": "Rhodanese domain-containing protein CG4456", "aln": "-------------------------------------------------------------MATYEQVKDVPNHPD--VYLIDVRRKEELQQTGFIPASINIPLDELDKALNLDGSAFKNKYGRSKPEKQSP-IIFTCRSGNRVLEAEKIAKSQGYSNVVIYKGSWNEWAQKEGL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08742-1", "uniprot_id": "RDL2_YEAST", "id": "Q08742-1", "name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "aln": "------MFKHSTGILSRTVSARSPTLVLR------------------------TFTTKAPKIYTFDQVRNLVEHPNDKKLLVDVR-EPKEVKDYKMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPP-HDKELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12305-1", "uniprot_id": "RDL1_YEAST", "id": "Q12305-1", "name": "Thiosulfate:glutathione sulfurtransferase", "aln": "------MWKAVMNAWNGTESQSK--------------------------------NVSNIQSYSFEDMKRIVGKHDPNVVLVDVR-EPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPD-SAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGGDKLDL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: : *.*** . :* ::::* . : : *. * ::* * * * * . * *: . * *. :* ", "identical_positions": 18, "similar_positions": 23, "identity": "9.94%" }, { "cls_id": "homologset.agr.FB:FBgn0001229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35878-1", "uniprot_id": "HSPB2_RAT", "id": "O35878-1", "name": "Heat shock protein beta-2", "aln": "--MSGRTVPHAHPATAEY-EFANPSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAARAGEGGRAGASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPD---------PEEEEEVARVEP---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PR8-1", "uniprot_id": "HSPB2_MOUSE", "id": "Q99PR8-1", "name": "Heat shock protein beta-2", "aln": "--MSGRTVPHAHPATAEY-EFANPSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAARAGEGARAGASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPD---------PEEEEEIARVEP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23928-1", "uniprot_id": "CRYAB_RAT", "id": "P23928-1", "name": "Alpha-crystallin B chain", "aln": "---MDIAIHHPWIRRPFF-PFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSE-----------------------MRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQA----SGPER-----TIPIT---------REEKPAVTAAPKK--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23927-1", "uniprot_id": "CRYAB_MOUSE", "id": "P23927-1", "name": "Alpha-crystallin B chain", "aln": "---MDIAIHHPWIRRPFF-PFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPER-----TIPIT---------REEKPAVAAAPKK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02511-1", "uniprot_id": "CRYAB_HUMAN", "id": "P02511-1", "name": "Alpha-crystallin B chain", "aln": "---MDIAIHHPWIRRPFF-PFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPER-----TIPIT---------REEKPAVTAAPKK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8E3-1", "uniprot_id": "A0A8M9Q8E3_DANRE", "id": "A0A8M9Q8E3-1", "name": "Alpha-crystallin B chain", "aln": "---MDIAINPP-FRRILF-PIFFPRRQ----FGEHITEADVISS------LYSQRSSFLRSPSWMESGVSE-----------------------VKMEKDQFSLSLDVKHFAPEELSVKIIGDFIEIHAKHEDRQDGHGFVSREFLRKYRVPVGVDPASITSSLSSDGVLTVTGPLKLS----DGPERTI---AIPVT---------RDDKTTVAGPQKRKKLKQVWNKWRGAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24623-1", "uniprot_id": "CRYAA_RAT", "id": "P24623-1", "name": "Alpha-crystallin A chain", "aln": "---MDVTIQHPWFKRALG-PFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYR-QSLFR--TVLDSGISELMTHMWFVMHQPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSER-----AIPVS---------REEKPSSAPSS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24622-1", "uniprot_id": "CRYAA_MOUSE", "id": "P24622-1", "name": "Alpha-crystallin A chain", "aln": "---MDVTIQHPWFKRALG-PFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYR-QSLFR--TVLDSGISELMTHMWFVMHQPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSER-----AIPVS---------REEKPSSAPSS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02489-1", "uniprot_id": "CRYAA_HUMAN", "id": "P02489-1", "name": "Alpha-crystallin A chain", "aln": "---MDVTIQHPWFKRTLG-PFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYR-QSLFR--TVLDSGISE-----------------------VRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAER-----AIPVS---------REEKPTSAPSS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22979-1", "uniprot_id": "HSP6C_DROME", "id": "P22979-1", "name": "Heat shock protein 67B3", "aln": "MPDIPFVLNLDSPDSMYYGHDMFPNRMYRRLHSRQHHDLDLHTLGLIARMGAHAHHLVANKRNGELAALSR---------------------GGASNKQGNFEVHLDVGLFQPGELTVKLVNECIVVEGKHEEREDDHGHVSRHFVRRYPLPKEFDSDAIVSTLSEDGVLNITVPPLVS--KEELKERIIPIKHVGPSDLFQNGNGHKEAGPAASASEPEAK------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * * ... :: . . :. *. ....* *** * * ::.*: : : : .:* :* * **.:**.* * * :* .* : .:** **:*.. * * : : ", "identical_positions": 29, "similar_positions": 39, "identity": "12.39%" }, { "cls_id": "homologset.agr.FB:FBgn0001230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "MSK---AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--GKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPG----GFPGGAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "MSK---AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--GKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPG----GFPGGAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "MSK---AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--SQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGA-AGGAPGAGPVPG-----AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "MSR---AVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKK--GRAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGESGGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14659-1", "uniprot_id": "HSP72_RAT", "id": "P14659-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQGGPGGGGSSG---------------------GPTIEEVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O97125-1", "uniprot_id": "HSP68_DROME", "id": "O97125-1", "name": "Heat shock protein 68", "aln": "MPA----IGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDAKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEKYAEEDERHRQRIAARNQLETYLFGVKEAAENGG--DRISAADKSSIVERCSEAMKWLDSNTTAEKEEYEYKLKELEQFCSPIMTKMHKGGGDGQQAPNFGQQ------------AGGYKGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :***********. * .:*:*************:*.***:***********.*:** *::*********.*:*. : * **:**:::. .*** :.**:** * * **:****:* **** ** :** *:.**:******************:*:*:*************:******: *: **************:*:*::* :***::*************.*:*..: ***** ***: * *::******.*****:****:::*:***:*:** ***:.::******* .****.**:****.* *:*:**.*:.:************:*:*: ::*.** * *************:***** **:* :*:**:**:***********:** ** **: ** *::: *:**:***..* :**:****: *****:**.*:*:*:********:*:****:*:******:* ::.**: ::***.*******: **::*: ***:: :** . :*: ::* :*: : :*:: .: :: * : ..:.: *** . * .:*:. : ***: ...**::*:: . . ***:****", "identical_positions": 373, "similar_positions": 161, "identity": "56.95%" }, { "cls_id": "homologset.agr.FB:FBgn0001233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07901-1", "uniprot_id": "HS90A_MOUSE", "id": "P07901-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKE---SDDKPEIEDVGSDEEEEEK---------------------------------------KDGDKKKK----KKIKEKYIDQE--------------------ELNKTKP--------IWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP-----------------PLEGDDDTSRMEEVD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQP6-1", "uniprot_id": "A0A8I5ZQP6_RAT", "id": "A0A8I5ZQP6-1", "name": "", "aln": "----------------------------------------------------------------------------------WTRGRSCTLISFPTSKTEPSLLRN---------------------------------------------------------------------------------------------------------------------------VSDDEAEEKEEKEEEKEKEEKE---SDDKPEIEDVGSDEEEEEK---------------------------------------KDGDKKEK----KKIKEKYIDQE--------------------ELNKTKP--------IWTRNPDDITNEEYGEFYKSLTNDWKEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVQRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISHEMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSAFGDEMVSLKDYCTRMKENQKHIYFITGETKDQV-----------HGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSSCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYKTALLSSSFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP-----------------PLEGDDDISRMEEVD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P82995-1", "uniprot_id": "HS90A_RAT", "id": "P82995-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKE---SDDKPEIEDVGSDEEEEEK---------------------------------------KDGDKKKK----KKIKEKYIDQE--------------------ELNKTKP--------IWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP-----------------PLEGDDDTSRMEEVD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15108-1", "uniprot_id": "HSC82_YEAST", "id": "P15108-1", "name": "ATP-dependent molecular chaperone HSC82", "aln": "--------------MAGETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVN--ERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVPIPEEEKKDEEKKDE------DDKKPKLEEVDEEEEE---------------------------------------------KKPKT----KKVKEEVQELE--------------------ELNKTKP--------LWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDEETETAPEAST-EAP-------------------VEEVPADTEMEEVD-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02829-1", "uniprot_id": "HSP82_YEAST", "id": "P02829-1", "name": "ATP-dependent molecular chaperone HSP82", "aln": "--------------MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVN--ERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKD-EDDKKPKLEEVDEEEE----------------------------------------------KKPKT----KKVKEEVQEIE--------------------ELNKTKP--------LWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEAST-AAP-------------------VEEVPADTEMEEVD-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02828-1", "uniprot_id": "HSP83_DROME", "id": "P02828-1", "name": "Heat shock protein 83", "aln": "------------MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNS---EPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEV--SDDEADDEKKEGDEKKE-METDEPKIEDVGEDEDADKK----------------------------------------DKDAKKK----KTIKEKYTEDE--------------------ELNKTKP--------IWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADAD-KNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSL-----------------VEDTEDASHMEEVD-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6GLF3-1", "uniprot_id": "A0A8I6GLF3_RAT", "id": "A0A8I6GLF3-1", "name": "", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKS---------------------------------------------------------------------------------EDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKE---DEEKPKIEDVGSDEEDES----------------------------------------SKDKKKKT----KTIKEKSIDQE--------------------ELNKTKP--------IWTRNPDDITQEEYGEFYKSLTNAWEDHLAMT----------------------------------------------------------------------------------------------------------------------------------------------------SLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEAD-TNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDE--VTAEELSAAVRE--EIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58FF8-1", "uniprot_id": "H90B2_HUMAN", "id": "Q58FF8-1", "name": "Putative heat shock protein HSP 90-beta 2", "aln": "-----MPEEVHLGEKEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNTQEHTLTLVDTGIGMTKADLINNLGTIAKF---------------------------------------------------------------------------------QDQTEYLEEMQVKEVVEKHSQFLGYPITLYLEKEREKEISDGKAEEEKGEKEEENKD---DEEKPKIEDVGSDEEDDS----------------------------------------GKDKKKKT----KKIKEKYIDQE--------------------ELNKTKP--------IWTRNTEDITQEEYGEFYKSLTNDWKDHLAVRYF--------------------------------------------------------------------------------------------------------------------------------------------------SVEEYVSRMKEIQKSIYYITGESKEQVANSAFVEQVWKRDSRVVYMTEPIDGY---QLKEFDGKSLVSVTKEGLELPEDGEEKKRMEERKAKFENLCKFMKETLDKKVEMVTVSNRLVSSSCCIVTSTYSWTANMEQIMKA---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11499-1", "uniprot_id": "HS90B_MOUSE", "id": "P11499-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG---EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKE---DEEKPKIEDVGSDEEDDS----------------------------------------GKDKKKKT----KKIKEKYIDQE--------------------ELNKTKP--------IWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VTAEEPSAAVPD--EIPP-------------LEGDEDASRMEEVD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08238-1", "uniprot_id": "HS90B_HUMAN", "id": "P08238-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG---EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKD---DEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQ------------------------------------------------------------------------QSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VAAEEPNAAVPD--EIPP-------------LEGDEDASRMEEVD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58FF7-1", "uniprot_id": "H90B3_HUMAN", "id": "Q58FF7-1", "name": "Putative heat shock protein HSP 90-beta-3", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLISLIINTFYSNEEIFLQELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLALVDTGIGMTKADLINNLRTIAKSGTKACMEALQA---------------------EKLVVITKHNDDEQYAWESSAGGSFTVHADHG---EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEQDKEISDDEAEEEKGEKEEEDKD---DEEKPKIKDVGSDEEDDS-------------------------------------KEYGEFYKSLTSDWEDHLAVKHFSVEGQLEFRALLFSPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIHGVVDSEDLPLNISREMLQ------------------------------------------------------------------------QSKILK---------------------------------------------------------------------YVSHMKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTDEDE--VAAEEPSDAVPD--EIPP-------------LEGDEDASRMEEVD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34058-1", "uniprot_id": "HS90B_RAT", "id": "P34058-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHG---EPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKE---DEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQ------------------------------------------------------------------------QSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD-KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDE--VTAEEPSAAVPD--EIPP-------------LEGDEDASRMEEVD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58FF6-1", "uniprot_id": "H90B4_HUMAN", "id": "Q58FF6-1", "name": "Putative heat shock protein HSP 90-beta 4", "aln": "-----------------------------MSLIINTFYSNKEIFLQELISNASDALDKIRYESLTDPSKLDGGKELKIDIIPNPRECILTLVNTGIGMTKADLINNLGAIAKSGTEAFMEAFQSCAEISMIGQFGVG-FYSAYLVAEKVAITKHNDEEQYSWVSSAGSSFTLHVDHG---EPIDRDTKVILHLKEDQTEYLEERWVKEVVKKHPQFIGCLIAVYLEKEPEKEISDD--EEEKGEKEEEDKD---DKEKPKTEDVGSDEEDDT----------------------------------------DKNNKKKT----KKIKEKYTDRE--------------------ELNQTKP--------IWTRNPDDITQEECGEFYKSLTSAWEDHLAVKQFPVEEQEENE-----------------------------------------------------------------QLCVHHVWIMDSFDDLMPEYVGFVREDKENNKKLDEVFSKISWLGIHEDSINWRHLSELLWSHTFQSGDEMTSLSEYVSCMKEAQKSICDIIGECKEQVANSAFVEQEWKKGFEVIYMSEPIDEYCVQQLKEFDGKSLLSVTKEGLELPEDEEEKKIMEESNVKFENLCRLMKEILDKKVERVTISSRLVSSPCRIVTSTYS--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57521-1", "uniprot_id": "HS90B_DANRE", "id": "O57521-1", "name": "Heat shock protein HSP 90-beta", "aln": "-----MPEEMRQ-EEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHG---EPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEISDDEAEEEKAEKEEKEEE---GEDKPKIEDVGSDDEEDTK---------------------------------------DKDKKKKK-----KIKEKYIDQE--------------------ELNKTKP--------IWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEAD-KNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPE--DIPP-------------LEGDDDASRMEEVD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90474-1", "uniprot_id": "H90A1_DANRE", "id": "Q90474-1", "name": "Heat shock protein HSP 90-alpha 1", "aln": "---MPEKSAQPVMEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFG---ESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVDLEEGEKQEEEEVAAGED----KDKPKIEDLGADEDEDS--------------------------------------------KDGKNKRKKKVKEKYIDAQ--------------------ELNKTKP--------IWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEAD-KNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDDSVVEEISQPAEEDMP-----------------VLEGDDDTSRMEEVD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q58FG1-1", "uniprot_id": "HS904_HUMAN", "id": "Q58FG1-1", "name": "Putative heat shock protein HSP 90-alpha A4", "aln": "------------------------------------------------------------MESLTDPSKLDSGKEPHISLIPNKQDRTLTIVDTGIGMTKADLINNLGTITKSETKVFMEVLQAGADISMIGQFSVGFYSAYSVAEKVTVITKHNNDEQYAWESSLRGSFT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYREFYKSLTINWEDYLAVKHFSVEGQLEFRAFLFVPRLAPFELLETRKKKNKIKLSARRDLIMDNCEELIPEYLNFIRGVVDSEDLPLNIFR------------------------------------------------------------------------------------------------ETKDQVANSTIVQRLWKHGLEVIYTIEPIDEYCVQQLKEFEGKTLVSVTKEDLELPEDEEEKKKQEEGKQKTK----------QKKNQSLRTS----------AKSTYGWTANMERIMKAQALRDNSTTGYMAAKKHLEINPDHSFIDTLRQKAETD-KNDKSVKDLVILLYETALLSSDFGLEGPQTHANRIYRMNKLGLGTDEDDPTADDTSAAVTEEMP-----------------PLEGDDDTSRMEK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07900-1", "uniprot_id": "HS90A_HUMAN", "id": "P07900-1", "name": "Heat shock protein HSP 90-alpha", "aln": "MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTG---EPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK----------------------------------------DGDKKKK----KKIKEKYIDQE--------------------ELNKTKP--------IWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD-KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP-----------------PLEGDDDTSRMEEVD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58FG0-1", "uniprot_id": "HS905_HUMAN", "id": "Q58FG0-1", "name": "Putative heat shock protein HSP 90-alpha A5", "aln": "------------------------------------------------------------------------------------------MGFHHVGQAGLELLTSGHPALER-----------------------------------------------------------------------------------RPEYLEERRIKEIVKKHSQFIGYPITLFVEKKRNKQVSDAEAEKKEDKRKKKKES----NDKPEIEDVGSDEEEEKK----------------------------------------DADKKKK-----KSKEKYIDQE---------------------LNKTKP--------IWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEGQLE-------------------------------------------------------------------------------------------------------------------------------------------ELKDSRRVMKANQKHIYYITGETKDQVANSAFVECLQKHGLEVIYMIELIDKYCVQQLKELESKTVVSVAKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDMLEKKVKKVVVSN---------------------------------------------------------------------------------------CMEDPQRHTNKIYRMIKLGLGVDEYDPTANDINAAITKEMP-----------------PLRGGDDTSRMEEVGGSG----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .*: . * * :.: . * : * . * . .*: : ** * :**: ..* ::.::*: :** * .** :: : : .: : : . ", "identical_positions": 19, "similar_positions": 37, "identity": "2.28%" }, { "cls_id": "homologset.agr.FB:FBgn0001235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2T5-1", "uniprot_id": "D4A2T5_RAT", "id": "D4A2T5-1", "name": "", "aln": "MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRPI----PPVHHLNHGPPLHATQHYG----------AHAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPG------VAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------SSKSDHEELSGSSTNLADHN------------PSSWRDHDDATSTHSAGTPGPSS------------GGHAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPVGMGMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97367-1", "uniprot_id": "MEIS2_MOUSE", "id": "P97367-1", "name": "Homeobox protein Meis2", "aln": "MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRPI----PPVHHLNHGPPLHATQHYG----------AHAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPG------VAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------SSKSDHEELSGSSTNLADHN------------PSSWRDHDDATSTHSAGTPGPSS------------GGHAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMGMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMVMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14770-1", "uniprot_id": "MEIS2_HUMAN", "id": "O14770-1", "name": "Homeobox protein Meis2", "aln": "MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRPI----PPVHHLNHGPPLHATQHYG----------AHAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPG------VAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------SSKSDHEELSGSSTNLADHN------------PSSWRDHDDATSTHSAGTPGPSS------------GGHAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AK57-1", "uniprot_id": "A0A8M3AK57_DANRE", "id": "A0A8M3AK57-1", "name": "", "aln": "MAQ-RYDELAHYGGMDGVG----MYGDPHAPRPL----PQVHHLNHGPPLHASQHYG----------THAPHPNVMPTS--MGSAVNDVLKRDKDQIYGHPLFPLLALVFEKCELATCTPREPG------VAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDG------SSKSDHEELSGSSTNLADHMGNGWIRSDRLQNPASWRDHDDATSTHSAGTPGPSS------------GGLAS------------------------QSGDNS-----------------SEQGDGLDNSVASPGT-GDDDDPDKDKKRQKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPS--------------------VSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSG----------MGMNMG------------------------------------------------MDGQWHYM---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O00470-1", "uniprot_id": "MEIS1_HUMAN", "id": "O00470-1", "name": "Homeobox protein Meis1", "aln": "MAQ-RYDDLPHYGGMDGVGIPSTMYGDPHAARSM----QPVHHLNHGPPLHSHQYP------------HTAHTNAMAPS--MGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPG------VAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREG------GSKSDSEDITR-SANLTDQP-------------SWNRDHDDTASTRSGGTPGPSS------------GGHTS------------------------HSGDNS-----------------SEQGDGLDNSVASPST-GDDDDPDKDKKRHKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA---------------------------VSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSG----------MGMNMG---------------------------------------------------------------MEGQWHYM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60954-1", "uniprot_id": "MEIS1_MOUSE", "id": "Q60954-1", "name": "Homeobox protein Meis1", "aln": "MAQ-RYDDLPHYGGMDGVGIPSTMYGDPHAARSM----QPVHHLNHGPPLHSHQYP------------HTAHTNAMAPS--MGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPG------VAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREG------GSKSDSEDVTR-SANLTDQP-------------SWNRDHDDTASTRSGGTPGPSS------------GGHTS------------------------HSGDNS-----------------SEQGDGLDNSVASPST-GDDDDPDKDKKRHKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA---------------------------VSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSG----------MGMNMG---------------------------------------------------------------MEGQWHYM------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GI80-1", "uniprot_id": "A0A8I6GI80_RAT", "id": "A0A8I6GI80-1", "name": "", "aln": "MAQ-RYDDLPHYGGMDGVGIPSTMYGDPHAARSM----QPVHHLNHGPPLHSHQYP------------HTAHTNAMAPS--MGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPG------VAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREG------GSKSDSEDVTR-AANLTDQP-------------SWNRDHDDTASTRSGGTPGPSS------------GGHTS------------------------HSGDNS-----------------SEQGDGLDNSVASPST-GDDDDPDKDKKRHKKRG---IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGKSPLVTVFKSGKRKPTSSHSPGGLLPVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQAQMPPHPAQLRHGPPMHTYIPGHPHHPAVMMHGGQP-HPGMPMSASSPSVLNTGDPTMSGQVMNIHAQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NDR6-1", "uniprot_id": "ME3L1_HUMAN", "id": "A6NDR6-1", "name": "Putative homeobox protein Meis3-like 1", "aln": "-------------------------------------------------------------------------------------------------------------------------MGPELGWGHPRGGDVCSSDSFNEDNTAFAKQVRSERPFFSSNPELDNLMIQAIQVLRFHLLELE-----------------KGKMPIDLVIEDRDG------GCREDFEDYPASCPSLPDQN------------NIWIRDHEDSGSVHLG-TPGPSS------------GGLAS------------------------QSGDNS-----------------SDQGVGLDTSVASPSSGGEDEDLDQEPRRNKKRG---IFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG----------------------------QGAAFSPEGQPIGGYTET-EPHVAFRAPA-------------SVGMSLN---------------------------------------------------------------SEGEWHYL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8K0S8-1", "uniprot_id": "ME3L2_HUMAN", "id": "A8K0S8-1", "name": "Putative homeobox protein Meis3-like 2", "aln": "MAR-RYDELPHYPSIADGPAALAGFPEAVPAAP-------GPYGPHRP------------------------PQPLPPG--LDS---DGLKRDKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPRGGDVCSSDSFNEDNTAFAKQVRSERPFFSSNPELDNLMIQAIQVLRFHLLELE-----------------KGKMPIDLVIEDRDG------GCREDFEDYPASCLSLPDQN------------NIWIRDHEDSGSVHLG-TPGPSS------------GGLAS------------------------QSGDNS-----------------SDQGVGLDTSVASPSSGGEDEDLDQEPRRNKKRG---IFPKVATNIMRAWLFQHLWHPYPSEEQKKQLVQDTGLTILQVNNWFINARRRMVQPMIDQSNRIG----------------------------QGAAFSPEGQPIGGYTET-EPHVAFRPPA-------------SVGMSLN---------------------------------------------------------------LEGEWHYL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99687-1", "uniprot_id": "MEIS3_HUMAN", "id": "Q99687-1", "name": "Homeobox protein Meis3", "aln": "MAR-RYDELPHYPGIVDGPAALASFPETVPAVP-------GPYGPHRP------------------------PQPLPPG--LDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDG------GCREDFEDYPASCPSLPDQN------------NMWIRDHEDSGSVHLG-TPGPSS------------GGLAS------------------------QSGDNS-----------------SDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRG---IFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG----------------------------QGAAFSPEGQPIGGYTET-QPHVAVRPPG-------------SVGMSLN---------------------------------------------------------------LEGEWHYL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97368-1", "uniprot_id": "MEIS3_MOUSE", "id": "P97368-1", "name": "Homeobox protein Meis3", "aln": "MAR-RYDELRHYPGITEHTTALASFSEAAPSVPR----APGPYTPHRP------------------------PQLQAPG--LDS---DSLKREKDDIYGHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDVCSSDSFNEDIAAFAKQIRSERPLFSSNPELDNLMVQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDG------SCREDLEDYAASCPSLPDQN------------TTWIRDHEDSGSVHLG-TPGPSS------------GGLAS------------------------QSGDNS-----------------SDQGDGLDTSVASPSSAGEDEDLDLERRRNKKRG---IFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG----------------------------QGASFNPEGQPMAGFTET-QPQVTVRTPG-------------SMGMNLN---------------------------------------------------------------LEGEWHYL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O46339-1", "uniprot_id": "HTH_DROME", "id": "O46339-1", "name": "Homeobox protein homothorax", "aln": "MAQPRYDDGLHGYGMDSGAAAAAMYDPHAGHRPPGLQGLPSHHSPHMTHAAAAAATVGMHGYHSGAGGHGTPSHVSPVGNHLMGAIPEVHKRDKDAIYEHPLFPLLALIFEKCELATCTPREPG------VQGGDVCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRG---IFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVY--------------------------TPHPGPSGYGHDAMGYMMDSQAHMMHRPPG-------------DPGFHQG-----------------------------------------------------------YPHYPPAEYYGQHL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53147-1", "uniprot_id": "TOS8_YEAST", "id": "P53147-1", "name": "Homeobox protein TOS8", "aln": "-----------------------------------------------------------------------------------------MGTSIVNLNQKIELPPIQVLFESLNRENETKPHFEER---RLYQPNPSFVPRTNIAVGSPVNPVPVSSPVFFIGPSPQRSIQNHNAIMTQNIRQYPVIYN------NNREVISTGERNYIITVGGPP-------VTSSQPEYEHISTPNFYQEQ-------------RLAQPHPVNESMMIGGYTNPQP--------IS------------------------------------------------------ISRGKMLSGNISTNSVRGSNNGYSAKEKKHKAHGKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQNDANNFR-------------------------------RKFSSSTNLAKF---------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41817-1", "uniprot_id": "CUP9_YEAST", "id": "P41817-1", "name": "Homeobox protein CUP9", "aln": "----------------------------------------------------------------------------------MNYNCEIQNRNSKNVDNQVSLPPIQVLFNSIEKRSMPELAFS-------------NIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATP-----------------------------------------TASTVETSKTSSSAMDTQS------------QYGSSKKSKSASDDAKPCYKSAP----------------------------------------------------------------IYEIINKEKDAGAQYNRPFSDFVESKSRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPN------------------------DNANNTPVERVQNVSAYHNTLSATNNTMYDATSTCSTDYELSKRFAHAPVTR--------------------------------------------------------RKKLIDRLEELKKLSNPDMN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . : * . . . . .: .: :.:: * :** :..*:. ** :*: :***: ::*::* .**** :*:.*****.*** : . . : ", "identical_positions": 27, "similar_positions": 39, "identity": "4.52%" }, { "cls_id": "homologset.agr.FB:FBgn0001247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHR7-1", "uniprot_id": "IDE_MOUSE", "id": "Q9JHR7-1", "name": "Insulin-degrading enzyme", "aln": "-----MRNGLVWLLHPALPGTLRSILGARPPPAKRLCGFPKQTYSTMSNP-----AIQRIEDQIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLLDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLRQLYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGYYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGKLH--YYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAIVSKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILSLE-KDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKRYNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEH-AHTKPLLPSQLVRYREVQLPDRGWFVYQ--QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNYDRDNIEVAYLKTLTKDDIIRFYQEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35559-1", "uniprot_id": "IDE_RAT", "id": "P35559-1", "name": "Insulin-degrading enzyme", "aln": "-----MRNGLVWLLHPALPSTLHSILGARPPPVKRLCGFPKQIYSTMNNP-----AIQRIEDHIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGKLH--YYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAIVSKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILALE-KDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEH-AHTKPLLPSQLVRYREVQLPDRGWFVYQ--RRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNYDRDNIEVAYLKTLSKDDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14735-1", "uniprot_id": "IDE_HUMAN", "id": "P14735-1", "name": "Insulin-degrading enzyme", "aln": "-----MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNP-----AIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILH--YYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLE-KEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEH-AHTKPLLPSQLVRYREVQLPDRGWFVYQ--QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IL71-1", "uniprot_id": "A0A0R4IL71_DANRE", "id": "A0A0R4IL71-1", "name": "Insulin-degrading enzyme", "aln": "-------------------MILSTVFGRSIRRVSTLS-------IRMSDP-----AVKRVVSDIIRSPEDKREYRGLEFTNGLKAILISDPTTDKSSAALDVHMGSLSDPENISGLAHFCEHMLFLGTEKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLQGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPKHPFSKFGTGNKLTLETRPSQQGIDIREELLKFHSTYYSSNLMGLCVLGRETLDELTSMVVKLFGEVENKNVPVPEFPTHPFQEEHLRQFYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIIFHMFQYIQKLRTEGPQEWVFQECKDLNTVAFRFKDKERPRGYTSKVAGLLH--YYPLEEILAAEYLLEEFRPDLIEMVLDKLRPENVRVAVVSKSFEGQTDRTEEWYGTQYKQEAITDEAIKKWDNADLNGKFKLPMKNEFIPTNFEIYPLE-KDSPSAPTLIKDTAMSKVWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTVYGMYLSVKGYNDKQHILLKKIIEKMATFEIDEKRFDIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELRDALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQSALEMMQMLEDTLIEH-AHTKPLLPSQLIRYREVQVPDGGWYVYQ--QRNEVHNNCGIEIYYQTDMQNTHENMLLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGVQGLRFIIQSEKAPHYLESRVEAFLKTMEKSVEEMGDEAFQKHIQALAIRRLDKPKKLAAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKEHIMQFYRDLLAIDAPRRHKVSVHVLSREMDSCPLVGEFPAQNDVNLAPAPSLPQPSLVQDMTEFKRSLPLFPLTKPHINFMAAKL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22817-1", "uniprot_id": "IDE_DROME", "id": "P22817-1", "name": "Insulin-degrading enzyme", "aln": "----------------------MTIAESSQKSATRKP--------DSMEP-----ILR--LNNIEKSLQDTRDYRGLQLENGLKVLLISDPNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGTEKYPHENGYTTYLSQSGGSSNAATYPLMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREINAVNSEHEKNLPSDLWRIKQVNRHLAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQWYSANIMCLAVIGKESLDELEGMVLEKFSEIENKNVKVPGWPRHPYAEERYGQKVKIVPIKDIRSLTISFTTDDLTQFYKSGPDNYLTHLIGHEGKGSILSELRRLGWCNDLMAGHQNTQNGFGFFDIVVDLTQEGLEHVDDIVKIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQ--IFPLEEVLIAPYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFEPDCDLAEPYYKTKYGITRVAKDTVQSWENCELNENLKLALPNSFIPTNFDISDVP-ADAPKHPTIILDTPILRVWHKQDNQFNKPKACMTFDMSNPIAYLDPLNCNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTIRGFSDKQVVLLEKLLDHLFDFSIDEKRFDILKEEYVRSLKNFKAEQPYQHSIYYLALLLTENAWANMELLDAMELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRVNTRLEATNASKLPILARQMLKKREYKLLAGDSYLFE--KENEFHKSSCAQLYLQCGAQTDHTNIMVNLVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANGIRIIVQSAKHPSYVEDRIENFLQTYLQVIEDMPLDEFERHKEALAVKKLEKPKTIFQQFSQFYGEIAMQTYHFEREEAEVAILRKISKADFVDYFKKFIAKDGEERRVLSVHIVSQQTDEN-------ATSEAEPVEITNMERHKPISDIVTFKSCKELYPIALPFLDIKAKGARSKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06010-1", "uniprot_id": "STE23_YEAST", "id": "Q06010-1", "name": "A-factor-processing enzyme", "aln": "MGVSLLASSSAFVTKPLLTQLVHLSPISLNFTVRRFKPFTCLSRYYTTNPYNMTSNFKTFNLDFLKPDLDERSYRFIELPNKLKALLIQDPKADKAAASLDVNIGAFEDPKNLPGLAHFCEHLLFMGSEKFPDENEYSSYLSKHGGSSNAYTASQNTNYFFEVNHQHLFGALDRFSGFFSCPLFNKDSTDKEINAVNSENKKNLQNDIWRIYQLDKSLTNTKHPYHKFSTGNIETLGTLPKENGLNVRDELLKFHKNFYSANLMKLCILGREDLDTLSDWTYDLFKDVANNGREVPLYAEPIMQPEHLQKIIQVRPVKDLKKLEISFTVPDMEEHWESKPPRILSHLIGHEGSGSLLAHLKKLGWANELSAGGHTVSKGNAFFAVDIDLTDNGLTHYRDVIVLIFQYIEMLKNSLPQKWIFNELQDISNATFKFKQAGSPSSTVSSLAKCLEKDYIPVSRILAMG-LLTKYEPDLLTQYTDALVPENSRVTLISRSLE--TDSAEKWYGTAYKVVDYPADLIKNMKSPGLNPALTLPRPNEFVSTNFKVDKIDGIKPLDEPVLLLSDDVSKLWYKKDDRFWQPRGYIYLSFKLPHTHASIINSMLSTLYTQLANDALKDVQYDAACADLRISFNKTNQGLAITASGFNEKLIILLTRFLQGVNSFEPKKDRFEILKDKTIRHLKNLLYEVPYSQMSNYYNAIINERSWSTAEKLQVFEKLTFEQLINFIPTIYEGVYFETLIHGNIKHEEALEVDSLIKSLIPNN----IHNLQVSNNRLRSYLLPKGKTFRYETALKDSQNVNSCIQHVTQLDVYSEDLSALSGLFAQLIHEPCFDTLRTKEQLGYVVFSSSLNNHGTANIRILIQSEHTTPYLEWRINNFYETFGQVLRDMPEEDFEKHKEALCNSLLQKFKNMAEESARYTAAIYLGDYNFTHRQKKAKLVANITKQQMIDFYENYIMSENASKLILHLKSQVENKELN--------ENELDTAKYPTG---QLIEDVGAFKSTLFVAPVRQPMKDFEISAPPKLNNSSESE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .: .: :. * *.** ::: * :*.:**.**.:* ::*:*.*::* :.** *:.**:*****:**:*::*:*.** *: :**: .***** * *:*.*.* ::* ******: ** .**: ...::*:***:**::**: .* **: *::: :..*.: **.:** ** *..:.:::*:******. :**:*:* :.::*:* ** * . . . * :: *:. :* :. *: : :: *:**::.* ::*. *: :.::* * * ******* **:*:.*: ** * * .* : .* ** : :***::** * *:: :***:: *: . *::*:*:* .:. *:**: * . .: . :. *:. :* * ::.***: * * *.: *:.::*:*:* * :* :* * * . : ::. .. ** :.*. *.*:.***.: : .. *.:: . : ::*.*:*::* *:. : :.: * :: . ::. : : * :* *:: * * *.* .. . *: :: :.:* :** :: : : *. .:.**:*:*: :* *:*: * *:.: * ::.* :*:. * :.:: :* :: * : . :: * ::.**:.:: * : :: : * . : *. : : :: .:. : .. : * . . . : *..*:: ***:: *********:***. . :* .:*:::** : . *:* *:: * * : :.:* : *::* :**. *:* *.: : ::: . * *:: : : :. : .::* .:: ::.. : : : : :: .: : .: : . . : :: ** : *: * :: ", "identical_positions": 252, "similar_positions": 356, "identity": "24.11%" }, { "cls_id": "homologset.agr.FB:FBgn0001248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88844-1", "uniprot_id": "IDHC_MOUSE", "id": "O88844-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGT--QKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEA-GFMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41562-1", "uniprot_id": "IDHC_RAT", "id": "P41562-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGS--QKVTYLVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEA-GFMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75874-1", "uniprot_id": "IDHC_HUMAN", "id": "O75874-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGT--QKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEA-GFMTKDLAACIKG-LPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7Z0E0-1", "uniprot_id": "B7Z0E0_DROME", "id": "B7Z0E0-1", "name": "Isocitrate dehydrogenase [NADP]", "aln": "MFALRRTAAMMTSVHRQPHLSQAVFRANFAISAADPKTHKISMDNERMSAVSEHSSVVCSPEQMAQKIKAGPVVDVLGDEMTRIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNVPRLVTGWQKPIVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDG---QVIDEVINDFK-GPGIALGMFNTDDSIVDFAHASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIES-GAMTKDLAICIKGNINAVTRRDYQETFEFINTLAKNLEGALAKNAVAAK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53982-1", "uniprot_id": "IDHH_YEAST", "id": "P53982-1", "name": "Isocitrate dehydrogenase [NADP]", "aln": "---------------------------------------------------------------MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGK--ENIDLKVYEFPKSGGIAMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVGGKMTKDLALMLGK----TNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41939-1", "uniprot_id": "IDHC_YEAST", "id": "P41939-1", "name": "Isocitrate dehydrogenase [NADP] cytoplasmic", "aln": "---------------------------------------------------------------MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDSATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRLVPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGT--HDVDLKVFDYPEHGGVAMMMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFESLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALILGK----SERSAYVTTEEFIDAVESRLKKEFEAAAL--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P21954-1", "uniprot_id": "IDHP_YEAST", "id": "P21954-1", "name": "Isocitrate dehydrogenase [NADP], mitochondrial", "aln": "-----------------------------------------------MSMLSRRLFSTSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQDAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDY-KGSGVAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGN----NERSAYVTTEEFLDAVEKRLQKEIKSIE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .:*:: *** **:**. *:.:*::*:::::*: ***.:: ** *.*::* *.: * *:.*.:********* *::**:*::********************.*: .:****. * ***:*****..***:*.* : *.: : :. . . : :: *:*: *:* .** .**::**: *:.: *: :*******:**.:**::*: :: .**.::: * *********** :**:**:: * *******:** ****:****:***:*: *****.*:**********:* :*:*:*****.*******:*.: :*.:***. : *.. **.. ::*:: * ****** * * * **:: : ..*: : ", "identical_positions": 194, "similar_positions": 123, "identity": "39.67%" }, { "cls_id": "homologset.agr.FB:FBgn0001250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7G7-1", "uniprot_id": "A0A8I6A7G7_RAT", "id": "A0A8I6A7G7-1", "name": "", "aln": "-----------------------------------------------------------------------MPPRQPTRRPGGGPSRELGKLLPALSHSPLGGLGSGSGSVAPGQGRTGAMGSWTPRSPRS----PLHAVLLRWGPRRLPPLLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVEFYRPG-----RDG-VSVLVGAPKAN--TSQPGVLQGGAVYVCPWGTSP-IQCSTIQFDSKGSRILESSLYS---EEPVEYKSLQWFGATVRAH---GSSILACAPLYSWRTEK---DPQNDPVGTCYLSTENF--TRILEYAPCRSDFGS--------AAGQGYCQGGFSAEFTKTG-RVVLGGPGSYFWQGQILSATQEQISESYYPQYL------------INPVQGQ-LQTRQASSVYDDSYLGYSVAVGEFSGDD-TEDFVAGVPKG---NLTYGYVTVLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQ-HPEGIEPTPSLTLTGQDEFGR-FGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLNTKPSQVLQP--LWAAGHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSM--FNPEERSCSLEGNP--VSCINLSFCLNASGK-HVPN--SIGFEVELQLDWQKQKGGVRRALFLASKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPK------APMDSHGLRPVLHYQSKSRIEDKAQILLDCGED-NICVPDLQLAVYG-------EKKHVYLGDKNALNLTFLAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNF-SSLSCDYFAVNQSRQLVCDLGNPMKAG-TSIWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQ---SNMVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQP-QKEGDLGPAVHHVYELINQGPSSISQGVLEISCPQALEGQ-QLLYVTK--VTGLNNCTSNYTPNSQGLELD-------PEVSPHHLQRR----EAPGRSSTTSGT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLKCP--EAKCFRLRCEFGPLHR--QESRSLQLHFRVWAKTFLQ---EYQPFSLQCEALYEALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKVSHTEPWLGFPPIRLCLLPRRIKEATLRSTLQAPISALATHTPSCLFLLDPSLQSAALGLQRDLLSQDKFAHIAKPQMANTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11688-1", "uniprot_id": "ITA5_MOUSE", "id": "P11688-1", "name": "Integrin alpha-5", "aln": "------------------------------------------------------------------------------------------------------------------------MGSWTPRSPRS----PLHAVLLRWGPRRLPPLLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVEFYRPG-----RDG-VSVLVGAPKAN--TSQPGVLQGGAVYVCPWGTSP-IQCTTIQFDSKGSRILESSLYSAKGEEPVEYKSLQWFGATVRAH---GSSILACAPLYSWRTEK---DPQNDPVGTCYLSTENF--TRILEYAPCRSDFGS--------AAGQGYCQGGFSAEFTKTG-RVVLGGPGSYFWQGQILSATQEQISESYYPEYL------------INPVQGQ-LQTRQASSVYDDSYLGYSVAVGEFSGDD-TEDFVAGVPKG---NLTYGYVTVLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQ-RPAGIDPTPTLTLTGQDEFSR-FGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLSTKPSQVLQP--LWAAGRTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSM--FNPEERSCSLEGNP--VSCINLSFCLNASGK-HVPN--SIGFEVELQLDWQKQKGGVRRALFLTSKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPK------APMDSHGLRPVLHYQSKSRIEDKAQILLDCGED-NICVPDLQLDVYG-------EKKHVYLGDKNALNLTFHAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNF-SSLSCDYFAVNQSRQLVCDLGNPMKAG-TSLWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQ---SNVVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQP-QKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQ-QLLYVTK--VTGLSNCTSNYTPNSQGLELD-------PETSPHHLQKR----EAPGRSSTASGT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLKCP--EAKCFRLRCEFGPLHR--QESRSLQLHFRVWAKTFLQR--EYQPFSLQCEAVYEALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKLGFFKRSLPYG------------TAMEKAQLKPPATSDA-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08648-1", "uniprot_id": "ITA5_HUMAN", "id": "P08648-1", "name": "Integrin alpha-5", "aln": "------------------------------------------------------------------------------------------------------------------------MGSRTPESP-------LHAVQLRWGPRRRPPLLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPG-----TDG-VSVLVGAPKAN--TSQPGVLQGGAVYLCPWGASP-TQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRAH---GSSILACAPLYSWRTEK---EPLSDPVGTCYLSTDNF--TRILEYAPCRSDFSW--------AAGQGYCQGGFSAEFTKTG-RVVLGGPGSYFWQGQILSATQEQIAESYYPEYL------------INLVQGQ-LQTRQASSIYDDSYLGYSVAVGEFSGDD-TEDFVAGVPKG---NLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQ-HPAGIEPTPTLTLTGHDEFGR-FGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQVLQP--LWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASASLTIFPAM--FNPEERSCSLEGNP--VACINLSFCLNASGK-HVAD--SIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPQ------APVDSHGLRPALHYQSKSRIEDKAQILLDCGED-NICVPDLQLEVFG-------EQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNF-SSLSCDYFAVNQSRLLVCDLGNPMKAG-ASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQ---SDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQP-QKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQ-QLLYVTR--VTGLN-CTTNHPINPKGLELD-------PEGSLHHQQKR----EAPSRSSASSGP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QILKCP--EAECFRLRCELGPLHQ--QESQSLQLHFRVWAKTFLQR--EHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYG------------TAMEKAQLKPPATSDA-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LZX9-1", "uniprot_id": "F1LZX9_RAT", "id": "F1LZX9-1", "name": "Integrin alpha-V", "aln": "------------------------------------------------------------------------------------------------------------------------MADPG-------------RLLLRPRPGGLLLLLLGLLLPFAG-----SFNLDVESPAEYAGPEGSYFGFAVDFFVPS-----TSSRMFLLVGAPKAN--TTQPGIIEGGQVLKCDCSSS--RRCQPIEFDSTGNRDYAK-------DDPLEFKSHQWFGASVRSK---QDKILACAPLYHWRTEM---KQEREPVGTCFLQDG----TKTVEYAPCRSKNID--------ADGQGFCQGGFSIDFTKAD-RVLLGGPGSFYWQGQLISDQVAEIISKYDPNVY------------SIKYNNQ-LATRTAQAIFDDSYLGYSVAVGDFNGDG-IEDFVSGVPRA---ARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ-RASG--DFQTTKLNGFEVFAR-FGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQILQG--QWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVYPSI--LNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPR--KLNFQVELLLDKLKQKGAIRRALFLHNRSPGHSKDMTVFRGGQTQCEELVAYLRDESEFRDKLTPITIFMEYRLDQR------TAADATGLQPILNQFTPANVSRQAHILLDCGED-NVCKPKLEVSVDS-------DQKKIYIGDDNPLTLTVKAQNQGEG-AYEAELIVSIPPQADFIGVVRNNEAL-ARLSCAFKTENQTRQVVCDLGNPMKAG-TQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNV---SPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWEYKETP-ETEEDVGPVVQHIYELRNNGPSSFSKAILNLQWPYKYNNN-TLLYILHYDIDGPMNCTADTEINPLRIKTP-----EKNDTAAE-QGGRNHLITKRDLSLSEGDV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HTLGCG--TAQCLQITCQVGRLDR--GKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKNLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ------------EEQEREQLQPHENGEGNSET---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43406-1", "uniprot_id": "ITAV_MOUSE", "id": "P43406-1", "name": "Integrin alpha-V", "aln": "------------------------------------------------------------------------------------------------------------------------MAAPG-------------RLLLRPRPGGLLLLLPGLLLPLAD-----AFNLDVESPAEYAGPEGSYFGFAVDFFEPS-----TSSRMFLLVGAPKAN--TTQPGIVEGGQVLKCECSSS--RRCQPIEFDSTGNRDYAK-------DDPLEFKSHQWFGASVRSK---QDKILACAPLYHWRTEM---KQEREPVGTCFLQDG----TKTVEYAPCRSKNID--------ADGQGFCQGGFSIDFTKAD-RVLLGGPGSFYWQGQLISDQVAEIISKYDPNVY------------SIKYNNQ-LATRTAQAIFDDSYLGYSVAVGDFNGDG-IEDFVSGVPRA---ARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ-RAVG--DFQTTKLNGFEVFAR-FGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGLVYIFNGRSTGLNSVPSQILEG--QWAAQSMPPSFGYSMKGATDVDRNGYPDLVVGAFGVDRAVLYRARPVVTVNAGLEVYPSI--LNQDNKICPLPGTALKVSCFNVRFCLKADGKGTLPR--KLHFQVELLLDKLKQKGAIRRALFLHNRSPVHSKTMTVFRGGQMQCEELVAYLRDESEFRDKLTPITIFMEYRLDQR------TAADATGLQPILNQFTPANVSRQAHILLDCGED-NVCKPKLEVSVNS-------DQKKIYIGDDNPLTLTVKAQNQGEG-AYEAELIVSIPPQADFIGVVRNNEAL-ARLSCAFKTENQTRQVVCDLGNPMKAG-TQLLAGLRFSVHQQSEMDTSVKFDLKIQSSNSFDNV---SPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWEYKENP-ETEEDVGPIVQHIYELRNNGPSSFSKAILNLQWPYKYNNN-TLLYILHYDIDGPMNCTADTEINPLRIKTP-----EKNDTAAAGQGERNHLITKRDLTLREGDV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HTLGCG--IAKCLQITCQVGRLDR--GKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNIIEFPYKNLPIEDLFNSTLVTTNITWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ------------EEQEREQLQPHENGEGNSET---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06756-1", "uniprot_id": "ITAV_HUMAN", "id": "P06756-1", "name": "Integrin alpha-V", "aln": "------------------------------------------------------------------------------------------------------------------------MAFPP-------------RRRLRLGPRGLPLLLSGLLLPLCR-----AFNLDVDSPAEYSGPEGSYFGFAVDFFVPS-----ASSRMFLLVGAPKAN--TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAK-------DDPLEFKSHQWFGASVRSK---QDKILACAPLYHWRTEM---KQEREPVGTCFLQDG----TKTVEYAPCRSQDID--------ADGQGFCQGGFSIDFTKAD-RVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVY------------SIKYNNQ-LATRTAQAIFDDSYLGYSVAVGDFNGDG-IDDFVSGVPRA---ARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ-RASG--DFQTTKLNGFEVFAR-FGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEG--QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI--LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPR--KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR------TAADTTGLQPILNQFTPANISRQAHILLDCGED-NVCKPKLEVSVDS-------DQKKIYIGDDNPLTLIVKAQNQGEG-AYEAELIVSIPLQADFIGVVRNNEAL-ARLSCAFKTENQTRQVVCDLGNPMKAG-TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKV---SPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENP-ETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAG-QGERDHLITKRDLALSEGDI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HTLGCG--VAQCLKIVCQVGRLDR--GKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ------------EEQEREQLQPHENGEGNSET---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GID8-1", "uniprot_id": "A0A8I6GID8_RAT", "id": "A0A8I6GID8-1", "name": "Integrin alpha-8", "aln": "------------------------------------------------------------------------------------------------------------------------MSARTHRGP------PENWAPPFACLCCVSAVLG-MLWSPVS----LAFNLDVDKLTVYSGPEGSYFGYSLDFYIP------DARTASVLVGAPKAN--TSQPDIVEGGAVYYCPWPAERSAQCKQIPFDTTNNRKIRVNG----TKEPIEFKSNQWFGATVRAH---KGKVVACAPLYHWRTLKP--NPAKDPVGTCYVAIQNF--SAYAEHSPCRNSNVD--------PEGQGYCQAGFSLDFYKNG-DLIVGGPGSFYWQGQVITVSVADIIANYSFKDI------------LRKLAAE-KQTDVAPASYDDSYLGKNHCS--STGSF-SEELVAGIPRG---AQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVYLYLQ-VSALLFQDPQ-VLTGTETFGR-FGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNARGLHSKPSQVLQG--IWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGEGKVAVYRARPVVTVDAQLLLHPMI--INLENKTCQIPEFPTPVACTAFTQCFSQHGFVHSLSVCPLALMAEVQLDFLKQKGAIKRTLFLHNHQSHLIFPFVMRQQKSLHCQDFMVYLRDETEFRDKLSPINVSLNYSLDDS------TFEDGLEVKPILNHYRENVVTEQAHILVDCGED-NLCVPDLRLSARP-------DKQEIIIGDENHLMLIINARNEGEG-AYEAELFVMIPEEADYVGIERNNKGL-RLLSCEYKMENVTRMVVCDLGNPMVTG-TNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPD---SNFVSVQINVTAVAQVEIRGVSHPPQIVLPIHNWEPAEEP-HKEEEVGPLVEHIYELHNIGPSTISDSILEVGWPFSAREE-FLLYVFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPHLVRKRDVPVVQPHRQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAKILNCT--NIDCLQISCAVGRLGG--GESAVLKVRSRLWAHTFLQR--KNDPYALASLVSFEVKKIPYKEQPAKLPAGSTAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQDE-----------MTDREQLTSDKTPEA-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARA8-1", "uniprot_id": "ITA8_MOUSE", "id": "A2ARA8-1", "name": "Integrin alpha-8", "aln": "------------------------------------------------------------------------------------------------------------------------MSAGTHCGP------PGNRAPPFARLCCVSAALG-MLWSPAC----LAFNLDVDKLTVYSGPEGSYFGYSLDFYIP------DARTASVLVGAPKAN--TSQPDIVEGGAVYYCPWPSERSAQCKQIPFDTTNNRKIRVNG----TKEPIEFKSNQWFGATVRAH---KGKVVACAPLYHWRTLKP--NPAKDPVGTCYVAIQNF--SAYAEHSPCRNSNAD--------PEGQGYCQAGFSLDFYKNG-DLIVGGPGSFYWQGQVITVSIADIIANYSFKDI------------LRKLAAE-KQTDVAPASYDDSYLGYSVAAGEFTGDS-QQELVAGIPRG---AQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVYLYLQ-ASALLFQDPQ-VLTGTETFGR-FGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNPRGLHSKPSQVLQG--IWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGKGKVAVYRARPVVTVDAQLLLHPMI--INLENKTCQIPEFPTPVACFSVRVCASIAGQSISN---TIALLAEVQLDFLKQKGAIKRTLFLHNHQSHFTFPFVMKQQKSLHCQDFMVYLRDETEFRDKLSPINISLNYSLDDS------TFKDSLEVKPILNHYRDNVVTEQAHILVDCGED-NLCVPDLKLSARP-------DKHQIIIGDENHLMLIINARNEGEG-AYEAELFVIIPEEADYVGIERNNKGL-RPLSCEYKMENVTRMVVCDLGNPMVTG-TNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPD---SNFERVQINITAIAQVEIRGVSHPPQIVLPIHNWEPEKKP-HKEEEVGPLVEHIYELHNIGPSTISDSILDVGWPFSARDE-FLLYIFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPHLVRKRDVPVVQLHRQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PARILNCT--NIDCLQISCAVGRLGG--GESAVLKVRSRLWAHTFLKR--KNDHYALASLVSFEVKKMPYKEQPAKLPAGSTAVKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQDE-----------MTDREQLTSDKTPEA-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53708-1", "uniprot_id": "ITA8_HUMAN", "id": "P53708-1", "name": "Integrin alpha-8", "aln": "------------------------------------------------------------------------------------------------------------------------MSPGASRGP------RGSQAPLIAPLCCAAAALGMLLWSPAC----QAFNLDVEKLTVYSGPKGSYFGYAVDFHIP------DARTASVLVGAPKAN--TSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNG----TKEPIEFKSNQWFGATVKAH---KGKVVACAPLYHWRTLKP--TPEKDPVGTCYVAIQNF--SAYAEFSPCRNSNAD--------PEGQGYCQAGFSLDFYKNG-DLIVGGPGSFYWQGQVITASVADIIANYSFKDI------------LRKLAGE-KQTEVAPASYDDSYLGYSVAAGEFTGDS-QQELVAGIPRG---AQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQ-VSSLLFRDPQ-ILTGTETFGR-FGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQG--VWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMI--INLENKTCQVPDSMTSAACFSLRVCASVTGQSIAN---TIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDES------TFKEGLEVKPILNYYRENIVSEQAHILVDCGED-NLCVPDLKLSARP-------DKHQVIIGDENHLMLIINARNEGEG-AYEAELFVMIPEEADYVGIERNNKGF-RPLSCEYKMENVTRMVVCDLGNPMVSG-TNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPD---SNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEP-HKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDE-FLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAKILNCT--NIECLQISCAVGRLEG--GESAVLKVRSRLWAHTFLQR--KNDPYALASLVSFEVKKMPYTDQPAKLPEGSIVIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQED-----------MTDREQLTNDKTPEA-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PK29-1", "uniprot_id": "A0A8M9PK29_DANRE", "id": "A0A8M9PK29-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------MDYTRTHRAE------AMHSCLSRMRFRCFFLMLS---FFCEA----AAFNLDLEKPTVYNGPEGSYFGYSLDFYHPTQ----DRNVMSVLVGAPKAN--TSQPGIVEGGAVYYCPWPASDPDSCRQIPFDKANNRMIKVNG----TREPLEFKSHQWFGATVRTH---KGKVVACAPLYQWRTVKV--SSEMDPVGTCYVAVQNF--SAYAEYSPCRTNNPD--------PEGQGFCQAGFSVDFTKEG-TLVVGGPGSFYWQGQVITAGVAEILNGYSLKTI------------LRKVQGE-KQTVAASDTYDDSYLGYSVAVGEFTGDS-EQELVAGVPRG---AHNFGYVTVINATNLTFIQNFTGEQMASYFGYTIAVTDLNGDGLDDVLVGAPLYMDREFESKPREVGRVYLYLQ-EDVLLFSPPI-TLTGMHLFGR-YGSAIAPLGDINQDGYLDVAIGAPFAGEDRGGRVFIYNGQKSGLMLQASQVLKG--DWASSGIPAGFGFTLRGDSDLDNNQYPDLLVGAFGVSKVVAYRSRPVVTVDAQLILRPRI--LNPEDKSCRMPNSDIMVTCLSVNVCAKISGIGIPD---YVALRMELQLDWLKQRGAVKRVLFMDSHQHQRSQQLVLGQGDRQHCHNYSVYLRDEAEFRDKLSPISVTLNYSLDQS------SPPAGLQLRPVLDHYSKTFHHEQANILLDCGED-NMCIPDLKLSAKM-------DRTELIIGDDNLLMLTINAANEGEG-AYEAELHVTLPPEADYIGVERRREDL-QRLNCEHRTENDTRIVVCDLGNPMVAD-TNLSVGLRFSVARLEDAPPTIGFEVQIHSSNKDNSR---SVPVNLTLSIVARAEVEIRGVSHPAQVVLPFPRWEPKEKP-VREDEVGPQVQHIYELHNKGPSSISRTVLEVGWPSRYREE-HLLYALQVITDGPVHCSTNSSLNPLELETST-LQDTPELLGFLRNSSG-VTRRRRSVSIGQSYN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKTLNCS--NINCLMVECVVDRLDR--GQSAVIKFRSRLWAYTFLQR--RNDHYTLNSTVSFQVTAMPYRIKAETLPRQSKSIGTFVVWAIPDVSFAIPLWVIILAILLGLLVLAVLSLAMWKCGFFDRARPPKDDD----------VSDREQLTAEKSTDA-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6GGN2-1", "uniprot_id": "A0A8I6GGN2_RAT", "id": "A0A8I6GGN2-1", "name": "Integrin alpha-IIb", "aln": "------------------------------------------------------------------------------------------------------------------------MARAS------------CAWNTLWLLQWTPLFLGPSAAPPAW-----ALNLDSVKFSVYTGPNGSHFGFSVDFHKDS------HGSVSIVVGAPRAL--NANQ--EETGGVFLCPWKANN-GTCTSLLFDLRDETRKLS------LQTFQTFKTGQGLGASVLSW---NDVIVACAPWQHWNVLEKYDEAEKTPVGGCFVAELQS--GGRAEYSPCRSNTMSSVYSQG-FSGDKRYCEAGFSLAVTQAG-ELVLGAPGGYFFLGLLVRVPIENIISSYRPGTL------------LWHVSNQRFSYDSSNPVYFHGYRGYSVAVGEFDGDLSTTEYIFGAPTW---SWTLGAVEILDS-YYQTLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRVDRKLAEVGRVYLFLQPKGLQALSSPTLVLTGTQVYGR-FGSAIAPLGDLNRDGYNDVAVAAPYGGPSGQGQVLIFLGQSEGLSPRPSQVLDS--PFPTG---SGFGFSLRGSVDIDDNGYPDLIVGAYGASKVAVYRAQPVVMATVQLMVQDS---LNPTLKNCVLEQTKTPVSCFNVQMCVGATGHNIPQK---LHLKAELQLDLQKPR-QARRVLLLASRQASLTLSLDLGGRNKPICHTIKAFLRDEADFRDKLSPIVLSLNVSLPP----------EETGVAPAVVLHGVTHVQEQTRIILDCGED-NLCVPQLQLTATA-------GDSPLLIGADNVLELKVNASNDGEG-AYEAELAVHLPPGAHYIRAFSNVKGF-ERLVCTQKKENESRLALCELGNPMKKD-TRIGITMLVSVEILEEAGDSVSFQLQIRSKNSQNPN---SEAVLLPVAVRAEAAVELRGNSFPASLVVAAE--EVDKEQ-DGLDSWVSRVEHTYELHNNGPGTVNGLSLIIHLPGQSQPS-DLLYILDVQPKGGLLCSTQPPPKLLKVDRRLTTPSPSSIRRIHHDRDRREASPQGSKQ-TEQQD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVLVSCNG-SAPCTVVECELQEMVR--GQRAMVTVQATLGLSILRQR--PQEQFVLQSHAWFNVSSLPYSVPVVSLPSGQGLVQTHLLRALEERD--IPVWWVLVGVLGGLLLLTLLVLAMWKAGFFKRNRPPLE------------EEEEEE----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUM0-1", "uniprot_id": "ITA2B_MOUSE", "id": "Q9QUM0-1", "name": "Integrin alpha-IIb", "aln": "------------------------------------------------------------------------------------------------------------------------MARAS------------CAWHSLWLLQWTPLFLGPSAVPPVW-----ALNLDSEKFSVYAGPNGSHFGFSVDFHKDK------HGSVSIVVGAPRAL--NASQ--EETGAVFLCPWKANG-GKCNPLLFDLRDETRNLG------FQIFQTFKTGQGLGASVVSW---NDVIVACAPWQHWNVLEKRDEAEKTPVGGCFLAQLQS--GGRAEYSPCRANTMSSVYAES-FRGDKRYCEAGFSLAVTQAG-ELVLGAPGGYFFLGLLARVPIENIISSYRPGTL------------LWHVSNQRFTYDNSNPVFFDGYRGYSVAVGEFDGDPSTTEYVSGAPTW---SWTLGAVEILDS-YYQPLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPKGPQALSTPTLLLTGTQLYGR-FGSAIAPLGDLNRDGYNDIAVAAPYGGPSGQGQVLIFLGQSEGLSPRPSQVLDS--PFPTG---SGFGFSLRGAVDIDDNGYPDLIVGAYGASKVAVYRAQPVVMATVQLMVQDS---LNPTLKNCVLDQTKTPVSCFNIQMCVGATGHNIPQK---LHLKAELQLDLQKPR-QGRRVLLLASQQASLTLSLDLGGRDKPICHTTGAFLRDEADFRDKLSPIVLSLNVSLPP----------EETGGAPAVVLHGETHVQEQTRIILDCGED-DLCVPQLRLTATA-------GDSPLLIGADNVLELKIEAANDGEG-AYEAELAVHLPPGAHYMRALSNIEGF-ERLVCTQKKENESRVALCELGNPMKKD-TRIGITMLVSVENLEEAGESVSFQLQVRSKNSQNPN---SKVVMLPVAIQAEATVELRGNSFPASLVVAAE--EGDREQ-EDLDRWVSRLEHTYELHNIGPGTVNGLRLLIHIPGQSQPS-DLLYILDVQPQGGLLCSTQPSP---KVDWKLSTPSPSSIRPVHHQRERRQAFLQGPK--PGQQD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVLVSCDG-SASCTVVECELREMVR--GQRAMVTVQVMLGLSSLRQR--PQEQFVLQSHAWFNVSSLPYSVPVVSLPSGQARVQTQLLRALEERA--IPVWWVLVGVLGGLLLLTLLVLAMWKAGFFKRNRPPLE------------EDEEEE----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08514-1", "uniprot_id": "ITA2B_HUMAN", "id": "P08514-1", "name": "Integrin alpha-IIb", "aln": "------------------------------------------------------------------------------------------------------------------------MARAL------------CPLQALWLLEWVLLLLGPCAAPPAW-----ALNLDPVQLTFYAGPNGSQFGFSLDFHKDS------HGRVAIVVGAPRTL--GPSQ--EETGGVFLCPWRAEG-GQCPSLLFDLRDETRNVG------SQTLQTFKARQGLGASVVSW---SDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPES--GRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAG-ELVLGAPGGYYFLGLLAQAPVADIFSSYRPGIL------------LWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTW---SWTLGAVEILDS-YYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGR-FGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDS--PFPTG---SAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDS---LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQK---LSLNAELQLDRQKPR-QGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPP----------TEAGMAPAVVLHGDTHVQEQTRIVLDCGED-DVCVPQLQLTASV-------TGSPLLVGADNVLELQMDAANEGEG-AYEAELAVHLPQGAHYMRALSNVEGF-ERLICNQKKENETRVVLCELGNPMKKN-AQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPN---SKIVLLDVPVRAEAQVELRGNSFPASLVVAAE--EGEREQ-NSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS-DLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVLVSCD--SAPCTVVQCDLQEMAR--GQRAMVTVLAFLWLPSLYQR--PLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERA--IPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLE------------EDDEEGE---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZMQ3-1", "uniprot_id": "D3ZMQ3_RAT", "id": "D3ZMQ3-1", "name": "Integrin alpha-4", "aln": "------------------------------------------------------------------------------------------------------------------------MAAEAMCRPR-------PRGVALQEAVMLLLYFGVHFRVPTGH----SYNLDPESALLYQGPSGTLFGYSVVLHSHG-------TKRWLIVGAPTASW-LANASVVNPGAIYRCRIGKNPNQICEQLQLGS--PSGEPCG------KTCLEERDNQWLGVTISRQPGENGSIVTCG--HRWKNIFYMKNNNKLPTGVCYGMPSDLRTELSKRMAPCYQDFVR------KFGENFASCQAGISS-FYTQD-LIVMGAPGSSYWTGSVFVYNITTNKYKAFVDRQ------------NQVKFGS--------------YLGYSVGAGHFRNPH-TTEVVGGAPQHEQIGKAYIFSIDESE--LTIVYEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQS------TIREEGRVFVYINSGMGAVMVEMERVLVGSDKYAARFGESMANLGDIDNDGFEDIAIGAPQE-DDLRGAVYIYNGRVDGISSTYSQRIEG--RQISQ-SLRMFGQSISGQIDADNNGYVDVAVGAFQSDSAVLLRTRPVVIVEASLSHPES---VNRTKFDCTENGLL--SVCVDLKLCFSYKGKEVPGY-IVLFYNVSLDVHRKAES--PSRFYFFSNGTSDMITRSIRVSSSGEKCRTHQAFMRK--DVRDILTPIQVEATYHLGHHV-ITKRNTEEFPPLQPILQQKKEKDIIRK-TINFARFCAYENCSADLQVSAKVGFLKPYENKTYLAVGSMKTIMLNVSLFNAGDD-AYETTLNVQLPTGLYFIKILDLEE---KQINCDVTESSGVVKLACSLGYIYVDRLSRIDISFLLDVSSLSRAHEDLSINVHASCENEGKLDQVKDNRVTLVIPLRYEVMLAVHGFVTPTSFVYGSSEEN------EPEMCMAEKLNLTFHVINTGISMAPNVSVKIMVPNSFLPRNDKLFNVLDVQAT--MGQCQFEHYGRECALA-------------QQKGIAGTLTDLVKFLSKTDK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLYCMKADRHCLDFLCNFGKMES--GKEASVHIQLEGRPSILEMD--ETSSLKFEIKATAFPEPHPKVIELNK-DENIAHVYLEGLHHQRPKR-HFTIVIVTISLLLGLIVLLLISCVMWKAGFFKRQYKSILQ-----------EENRR----DSWSYVNSKSNDD------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00651-1", "uniprot_id": "ITA4_MOUSE", "id": "Q00651-1", "name": "Integrin alpha-4", "aln": "------------------------------------------------------------------------------------------------------------------------MFSTKSAWLRNGGADQGPRGIALREAVMLLLYFG----VPTGP----SYNLDPENALLYQGPSGTLFGYSVVLHSHG-------SKRWLIVGAPTASW-LSNASVVNPGAIYRCGIRKNPNQTCEQLQSGS--PSGEPCG------KTCLEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYMKSDNKLPTGICYVMPSDLRTELSKRMAPCYKDYTR------KFGENFASCQAGISS-FYTQD-LIVMGAPGSSYWTGTVFVYNITTNQYKAFVDRQ------------NQVKFGS--------------YLGYSVGAGHFRSPH-TTEVVGGAPQHEQIGKAYIFSIDENE--LNIVYEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQS------TIREEGRVFVYINSGMGAVMVEMERVLVGSDKYAARFGESIANLGDIDNDGFEDIAIGAPQE-DDLRGAVYIYNGRVDGISSTYSQRIEG--QQISK-SLRMFGQSISGQIDADNNGYVDVAVGAFQSDSAVLLRTRPVVIVEASLSHPES---VNRTKFDCTENGLP--SVCMHLTLCFSYKGKEVPGY-IVLFYNVSLDVHRKAES--PSRFYFFSNGTSDVITGSIRVSSSGEKCRTHQAFMRK--DVRDILTPIHVEATYHLGHHV-ITKRNTEEFPPLQPILQQKKEKDVIRK-MINFARFCAYENCSADLQVSAKVGFLKPYENKTYLAVGSMKTIMLNVSLFNAGDD-AYETTLNVQLPTGLYFIKILDLEE---KQINCEVTESSGIVKLACSLGYIYVDRLSRIDISFLLDVSSLSRAHEDLSISVHASCENEGELDQVRDNRVTLTIPLRYEVMLTVHGLVNPTSFVYGSSEEN------EPETCMAEKLNLTFHVINTGISMAPNVSVKIMVPNSFLPQDDKLFNVLDVQTT--TGQCHFKHYGRECTFA-------------QQKGIAGTLTDIVKFLSKTDK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLYCMKADQHCLDFLCNFGKMES--GKEASVHIQLEGRPSILEMD--ETSSLKFEIKATAFPEPHPKVIELNK-DENVAHVFLEGLHHQRPKR-HFTIIIITISLLLGLIVLLLISCVMWKAGFFKRQYKSILQ-----------EENRR----DSWSYVNSKSNDD------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13612-1", "uniprot_id": "ITA4_HUMAN", "id": "P13612-1", "name": "Integrin alpha-4", "aln": "------------------------------------------------------------------------------------------------------------------------MAWEARREPG-------PRRAAVRETVMLLLCLG----VPTGR----PYNVDTESALLYQGPHNTLFGYSVVLHSHG-------ANRWLLVGAPTANW-LANASVINPGAIYRCRIGKNPGQTCEQLQLGS--PNGEPCG------KTCLEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDYVK------KFGENFASCQAGISS-FYTKD-LIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQ------------NQVKFGS--------------YLGYSVGAGHFRSQH-TTEVVGGAPQHEQIGKAYIFSIDEKE--LNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQS------TIREEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE-DDLQGAIYIYNGRADGISSTFSQRIEG--LQISK-SLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPES---VNRTKFDCVENGWP--SVCIDLTLCFSYKGKEVPGY-IVLFYNMSLDVNRKAES--PPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRK--DVRDILTPIQIEAAYHLGPHV-ISKRSTEEFPPLQPILQQKKEKDIMKK-TINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDD-AYETTLHVKLPVGLYFIKILELEE---KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDEN------EPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTT--TGECHFENYQRVCALE-------------QQKSAMQTLKGIVRFLSKTDK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLYCIKADPHCLNFLCNFGKMES--GKEASVHIQLEGRPSILEMD--ETSALKFEIRATGFPEPNPRVIELNK-DENVAHVLLEGLHHQRPKR-YFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQ-----------EENRR----DSWSYINSKSNDD------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZN51-1", "uniprot_id": "D3ZN51_RAT", "id": "D3ZN51-1", "name": "Integrin alpha-9", "aln": "MWFIQVQHQVQAVLREPRPAGGAAGPSRQGRPGRPPLGRASPQSSAARAPDPLHRRAQSSRRGSRGRGALAASPGLFPARAAALPSVPGSDLECTARAPGSVVSREPRSRGRAQGGGRLGMGGPAAKGTG---------AGGLRALLLALVAAG----VPAG-----AYNIDAQRPVRFQGPPGSFFGYAVLEHFHD-------NTRWVLVGAPKADS-KYSTSVKSPGAVFKCRVHTNPDRRCTELDMARERNRGESCG------KTCRGDRDDEWMGVSLARQPKADGRVLACA--HRWKNIYYET-DHILPHGFCYLIPSNLQAKG-RMLIPCYEEYKK------KYGEEHGSCQAGIAG-FFTEE-LVIMGAPGSFYWAGTLKVLNLTDNTYFKLNDDA------------IMNRRYT--------------YLGYAVTAGHFSHPS-VTDVVGGAPQDEGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVGAPMFS------EIRDEGQVTVYLNQGHGVLEEQLT--LTGDAAYNAHFGESIASLGDLDDDGFPDVAVGAPME-DDFAGTVYIYHGDAQGIVPQYSMKLSG--RKINP-ILQMFGQSISGGIDMDGNGYPDVTVGAFLSDSVVLLRARPVITVDVSIFLPGS---INITAPQCHDGQQP--VNCLNVTVCFRFHGKNVPGE-IGLNYNLTADVAQKEKGQLPRVYFVLLGETAGQVSERLQLTHMDEVCHHYVAHVKR--RVQDVISPIVFEAAYSLGEHV-IGE-EDRELPDLTPVLRWKKGQRIAQKNQTVFERNCRSEDCAADLQLRGKLLLSSVDEKTTHLALGAVKNISLNISISNLGDD-AYDANVSFNVSRELFFINMWQKEE---MGISCELLESD---FLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEILSFIVTAQSGNMERSEALHDNTLTLTIPLVHEVDTSITGIVSPTSFVYGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFPSRLSPGGAEMFQVQDMVVSQEKGNCSLQRNPTPCIIP-------------QEQ--ENIFHTIFAFFSKSGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVLDCEKTGSFCLTLHCNLSALPK--EESRAIDLYMLLNTEILKKD--SSSVIQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLEPRG-YVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIE-----------AEKNRKENEEAWDWVQKNQ---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8JK39-1", "uniprot_id": "ITA9_MOUSE", "id": "B8JK39-1", "name": "Integrin alpha-9", "aln": "------------------------------------------------------------------------------------------------------------------------MGGPAAARTG---------AGGLRALLLALVAAG----VPAG-----AYNLDAQRPVRFQGPSGSFFGYAVLEHFHD-------NTRWVLVGAPKADS-KYSTSVKSPGAVFKCRVHTNPDRRCTELDMARGRTRGAPCG------KTCRGDRDDEWMGVSLARQPRADGRVLACA--HRWKNIYYEA-DHILPHGFCYLIPSNLQAKG-KVLIPCYEEYKK------KYGEEHGSCQAGIAG-FFTEE-LVVMGAPGSFYWAGTLKVLNLTDNTYFKLNDEA------------IMNRRYT--------------YLGYAVTAGHFSHPS-ITDVVGGAPQDEGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVGAPMFS------EIRDEGQVTVYLNQGHGALEEQLT--LTGDAAYNAHFGESIANLGDIDDDGFPDVAVGAPKE-EDFAGAVYIYHGDANGIVPKYSMKLSG--RRLNP-TLRMFGQSISGGIDMDGNGYPDVTIGAFLSDSVVLLRARPVITVDVSIFLPGS---INITAPQCHDGQQP--VNCLNVTVCFRFHGKNVPGE-IGLNYNLTADVAQKEKGQLPRVYFVLFGETAGQVSERLQLSHMDEVCHHYVAHVKR--RVQDVISPIVFEAAYSLDEHV-MGE-EDRELPDLTPVLRWKKGQRISQKNQTVFERNCQSEDCAADLQLRGKLLLSSVDEKTPHLALGAVKNISLNISISNLGDD-AYDANVSFNVSRELFFINMWQKEE---MGISCELLESD---FLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEILSFIVTAQSGNLERSEALHDNTLTLTVPLVHEVDTSITGIVSPTSFVYGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFPSRLSPGGAEMFQVQDMVVSQEKGNCSLQRNPTPCIIP-------------QEQ--ENIFHTIFAFFSKSGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVLDCEKPGSFCLTLHCNLSALPK--EESRTINLYMLLNTEILKKD--SSSVIQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLEPRG-YVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIE-----------AEKNRKENEDGWDWVQKNQ---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13797-1", "uniprot_id": "ITA9_HUMAN", "id": "Q13797-1", "name": "Integrin alpha-9", "aln": "------------------------------------------------------------------------------------------------------------------------MGGPAAPR-G---------AGRLRALLLALVVAG----IPAG-----AYNLDPQRPVHFQGPADSFFGYAVLEHFHD-------NTRWVLVGAPKADS-KYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCG------KTCREDRDDEWMGVSLARQPKADGRVLACA--HRWKNIYYEA-DHILPHGFCYIIPSNLQAKG-RTLIPCYEEYKK------KYGEEHGSCQAGIAG-FFTEE-LVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEV------------IMNRRYT--------------YLGYAVTAGHFSHPS-TIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFS------EIRDEGQVTVYINRGNGALEEQLA--LTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAVYIYHGDAGGIVPQYSMKLSG--QKINP-VLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGS---INITAPQCHDGQQP--VNCLNVTTCFSFHGKHVPGE-IGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKR--RVQDVISPIVFEAAYSLSEHV-TGE-EERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDD-AYDANVSFNVSRELFFINMWQKEE---MGISCELLESD---FLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIP-------------QEQ--ENIFHTIFAFFTKSGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVLDCEKPGISCLTAHCNFSALAK--EESRTIDIYMLLNTEILKKD--SSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRG-YVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIE-----------AEKNRKENEDSWDWVQKNQ---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12080-1", "uniprot_id": "ITA2_DROME", "id": "P12080-1", "name": "Integrin alpha-PS2", "aln": "------------------------------------------------------------------------------------------------------------------------MSGDSIHRRR----------MALHCPITSLILLLIAMSAHG-------YNIDLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVSLIVGAPKFDTSRYQQGVTEAGGVFKCSLNDDD---CKLVPFDSKGNNRNVD-------KEVVDRKSYQWLGATVATG-RDSDLVVACAPRYVFHTMTPSRAFRIDPVGTCFTSHN---FEEFYEVSPCRTNNWG--------YHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVFSTSESASVNDDSYLGYSMVTGDFDGDR-SEDVAIGMPRG----GNLVGRIVVNRWNMANIFNITGRQIGEYFGYSLATSDVDGDGLDDLLIGAPMYTDPDNVEGKYDVGRVYILLQGGPTEEKRWTTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMGPLAKPSQIIKSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWSYTGRYLPEQ-----LDFDVSWLLDAKKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCLNETVYLLD--KVQDKLTPLEVEARYNLRSSRPLDPMVRHRRSILEPVIDQNREIVLRDAINIQKNCGPD-NICEPDLKLKVST--------VDKYLFGSPEPLVIEVFISNTNED-AFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLKCDIGNPLESG-KIAHFKISLVPEEKYGSSSSYDFYWEANSTNLEKPGSEYDNKIRQSVGIWVDTDLDIKGTSLPDYQLYKADDYKELENA-TKEDDIGPQVVHIYEIRNNRPSIIEEAEVFIHLPYETIVGDPLMYLLNQPETGGKIQCDDVAFNEYNLLLDEKLVKKSYLQAQGAIWNSAQVSGQSSSSSSSGGASVHIEKARGEGFVRGVLVSNSTDAGDKLSPKQVEQRRQEDTLEALGDASFVHRDRASQAVQEPQVNQTSFTTYSTSSSSSGSGAPSAQLRGHSTQGHIQMAGPVQHTSSSSSSNYRSWPAQQQQQHQQLLLAGSGGSGLGSPVTFNDKSQFGGRNNNFHTGTLDLGTLNRGNVDNELYRSQGQYQNPSQSLGQSQGQFQANANQGHYQGQNQAQFQARNPGFQGQTSYQGQTQYSGQPGGYQTHHVTYSSGSKPYYGRENEDFYDEDNLQQATPGHWSSSSSSSSSSGTRRLRRSNDKDGATEKPLQIDLNSPCQSARCKSIRCVVTNLGTEDGDAAFVAIRARMVAKTMEKLA-SNVPLNVSTLAVANVTLLPFIGAPKDAIVKTHEIFYKAEPEPLQVPDVVPLWVVVLAACAGALIFLLLVWLLYKCGFFNRNRPTDHS------------QERQPLRNGYHGDEHL-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* . .: **::: . ::**** . . * : * * : : : :*.:: . :::*. :. * * *: ** . *:.*:: . :.:*.**. :: * * * : * * : . *.::. *** :: . * : *. *:::***: : *:: : :: : . :* ::. *.*:: **: *.*:..* * : :: * * * :. ** :: * * * * * *: :*:: . . : :*: . . .. * * . * * . . * .: .:* ::*: . * * : : * ..*.: .* : : : . * .:. *::: . . . : : * . *.:* . . : . * : : . : * * . : .: * . : : * :: : . * * . : . : . : . . : . : . * ::: :: ::: .. . ", "identical_positions": 86, "similar_positions": 175, "identity": "5.27%" }, { "cls_id": "homologset.agr.FB:FBgn0001258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04642-1", "uniprot_id": "LDHA_RAT", "id": "P04642-1", "name": "L-lactate dehydrogenase A chain", "aln": "--------------------------------------------------MAALKDQLIVNLLKEE-QVPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSSKDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGVNVAGVSLKSLNPQLGTDADKEQWKDVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGIKEDVFLSVPCILGQNGISDVVKVTLTPDEEARLKKSADTLWGIQKELQF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06151-1", "uniprot_id": "LDHA_MOUSE", "id": "P06151-1", "name": "L-lactate dehydrogenase A chain", "aln": "--------------------------------------------------MATLKDQLIVNLLKEE-QAPQNKITVVGVGAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLKTPKIVSSKDYCVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPHCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWVLGEHGDSSVPVWSGVNVAGVSLKSLNPELGTDADKEQWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGINEDVFLSVPCILGQNGISDVVKVTLTPEEEARLKKSADTLWGIQKELQF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00338-1", "uniprot_id": "LDHA_HUMAN", "id": "P00338-1", "name": "L-lactate dehydrogenase A chain", "aln": "--------------------------------------------------MATLKDQLIYNLLKEE-QTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19629-1", "uniprot_id": "LDHC_RAT", "id": "P19629-1", "name": "L-lactate dehydrogenase C chain", "aln": "--------------------------------------------------MSTVKEQLIQNLAPDE-KQSRCKITVVGVGNVGMACAISILLKGLADELALVDADENKLKGEALDLLHGSLFLSTPKIVFGKDYSVSANSKLVIITAGARMVSGESRLALLQRNVTSMKAIVPGVIQNSPDCKIMIVTNPVDILTYVVWKISGLPVSSVIGSGCNLDSARFRYLIGEKLGVNPSSCHGWVLGEHGDSSVPIWSGVNIAGVTLKSLNPAIGSDSDKEQWKTVHKQVVDGGYEVLNLKGYTSWAIALSVTDIAASILKNLKRVHAVTTLVKGLYGIKEEIFLSIPCVLGQSGITDLVKVNMNTEEEALFKKSCDILWNIQKDLQL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00342-1", "uniprot_id": "LDHC_MOUSE", "id": "P00342-1", "name": "L-lactate dehydrogenase C chain", "aln": "--------------------------------------------------MSTVKEQLIQNLVPED-KLSRCKITVVGVGNVGMACAISILLKGLADELALVDADTNKLRGEALDLLHGSLFLSTPKIVFGKDYNVSANSKLVIITAGARMVSGETRLDLLQRNVAIMKAIVPGIVQNSPDCKIIIVTNPVDILTYVVWKISGFPVGRVIGSGCNLDSARFRYLIGEKLGVNPTSCHGWVLGEHGDSSVPIWSGVNVAGVTLKSLNPAIGTDSDKEHWKNVHKQVVEGGYEVLNMKGYTSWAIGLSVTDLARSILKNLKRVHPVTTLVKGFHGIKEEVFLSIPCVLGQSGITDFVKVNMTAEEEGLLKKSADTLWNMQKDLQL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07864-1", "uniprot_id": "LDHC_HUMAN", "id": "P07864-1", "name": "L-lactate dehydrogenase C chain", "aln": "--------------------------------------------------MSTVKEQLIEKLIEDD-ENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLNSEEEALFKKSAETLWNIQKDLIF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYZ2-1", "uniprot_id": "LDH6B_HUMAN", "id": "Q9BYZ2-1", "name": "L-lactate dehydrogenase A-like 6B", "aln": "MSWTVPVVRASQRVSSVGANFLCLGMALCPRQATRIPLN-GTWLFTPVSKMATVKSELIERFTSEK-PVHHSKVSIIGTGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCSKDYFVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSNPVDILTYVAWKLSAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHGDSSVPVWSGVNIAGVPLKDLNSDIGTDKDPEQWKNVHKEVTATAYEIIKMKGYTSWAIGLSVADLTESILKNLRRIHPVSTIIKGLYGIDEEVFLSIPCILGENGITNLIKIKLTPEEEAHLKKSAKTLWEIQNKLKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZMR3-1", "uniprot_id": "LDH6A_HUMAN", "id": "Q6ZMR3-1", "name": "L-lactate dehydrogenase A-like 6A", "aln": "--------------------------------------------------MATIKSELIKNFAEEE-AIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGSPFMKMPNIVSSKDYLVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVTNPVDILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHGDSSVPVWSGVNIAGVPLKDLNPDIGTDKDPEQWENVHKKVISSGYEMVKMKGYTSWGISLSVADLTESILKNLRRVHPVSTLSKGLYGINEDIFLSVPCILGENGITDLIKVKLTLEEEACLQKSAETLWEIQKELKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TNA8-1", "uniprot_id": "Q7TNA8_RAT", "id": "Q7TNA8-1", "name": "L-lactate dehydrogenase", "aln": "MAWAVSILRARRRMGTVRVDFKDLGVALWPSQVLRVPPNRAWWSLTPTSTMATVKGKLLQHVSSEE-PVLHNKVSIIGTGSVGMACAISIIAKGLTDELALVDSNEGKMKGETMDLQHGSVFMKMPNIVCSKDFHVTANSEVVVITAGARQEKDETRLNLVQRNVSIFKIMFANIVKYSPRCKIIIVSNPVDILTYVAWKLSGFPKNRVIGSGCNLDTARFRYMLGQRLGIHSESCHGWVLGEHGDSSVPVWSGVNIAGVPLKELNSAIGTNKDPEQWGNVHKEVIASAYKIIKMKGYTSWAIGLSVADIAESILKNLRKTHPVSTKIKGLYGIKEEVFLSVPCVLGENGISDIIKVKLSPTEEAQMVKSADTIWKIQKDIKF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42123-1", "uniprot_id": "LDHB_RAT", "id": "P42123-1", "name": "L-lactate dehydrogenase B chain", "aln": "--------------------------------------------------MATLKEKLIAPVADDETAVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCTIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLRKSADTLWDIQKDLKDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16125-1", "uniprot_id": "LDHB_MOUSE", "id": "P16125-1", "name": "L-lactate dehydrogenase B chain", "aln": "--------------------------------------------------MATLKEKLIASVADDEAAVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCTIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLRKSADTLWDIQKDLKDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07195-1", "uniprot_id": "LDHB_HUMAN", "id": "P07195-1", "name": "L-lactate dehydrogenase B chain", "aln": "--------------------------------------------------MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PVK4-1", "uniprot_id": "LDHBA_DANRE", "id": "Q9PVK4-1", "name": "L-lactate dehydrogenase B-A chain", "aln": "--------------------------------------------------MASVMQKLITPLASGPAEPPRNKVTIVGVGQVGMACAVSVLLRELADELALVDVVEDRLKGEMLDLQHGSLFLKTPKIVADKDYSVTANSRIVVVTAGVRQQEGESRLNLVQRNVNIFKHIIPQIVKYSPDCILVVVSNPVDVLTYVTWKLSGLPKHRVIGSGTNLDSARFRYIMAEKLGIHASSFNGYILGEHGDTSVPVWSGANVAGVSLQKLNPDIGTDKDAENWKEAHKMVVDSAYEVIKLKGYTNWAIGLSVADLTETLVKNLNRVHPVSTMVKGMYGINEEVYLSLPCVLNSSGVGSVINMTLTDGEIGQLKSSADTLWGIQKDLKDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DGK2-1", "uniprot_id": "LDHBB_DANRE", "id": "Q6DGK2-1", "name": "L-lactate dehydrogenase B-B chain", "aln": "--------------------------------------------------MASVLQKLITPLFSGPLEPPRNKVTVVGVGQVGMACAVSVLLRELADELALVDVVEDKLKGEMMDLQHGSLFLKTPKIVSGKDYSVTANSRIVVVTAGVRQQEGESRLNLVQRNVNIFKHIIPQIVKYSPNCILIVVSNPVDVLTYVTWKLSGLPKHRVIGSGTNLDSARFRYLMAERLGIHPSSFNGWILGEHGDSSVPVWSGANVAGVSLQKLNPDIGKDTDRENWKETHKKVVDSAYEVIRLKGYTNWAIGLSVADLTESIMKNLNRVHPVSTMVKGMYGISDEVYLSLPCVLNSAGVGSVVNMTLTVDEVSQLKKSADMLWHIQRDLRDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9PVK5-1", "uniprot_id": "LDHA_DANRE", "id": "Q9PVK5-1", "name": "L-lactate dehydrogenase A chain", "aln": "--------------------------------------------------MASTKEKLIAHVSKEQPAGPTNKVTVVGVGMVGMAAAVSILLKDLTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVAWKLSGLPRNRVIGSGTNLDSARFRYLMGEKLGIHPSSCHGWVVGEHGDSSVPVWSGVNVAGVSLQALNPDLGTDKDKEDWKSVHKMVVDSAYEVIKLKGYTSWAIGMSVADLCESILKNMHKCHPVSTLVKGMHGVNEEVFLSVPCILGNNGLTDVVHMTLKPEEEKQLVKSAETLWGVQKELTL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95028-1", "uniprot_id": "LDH_DROME", "id": "Q95028-1", "name": "L-lactate dehydrogenase", "aln": "--------------------------------------------------MAAIKDSLLAQVAEVL-PSSGHKVTIVGIGQVGMASAFSILAQNVSKEVCLIDVCADKLQGELMDLQHGSNFLKNPQITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPDTILLMVSNPVDIMTYVAWKLSGLPKNRVIGSGTNLDSSRFRFLMSQRLGVAPTSCHGWIIGEHGDSSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIKLKGYTSWAIGLSTASLASAILRNTSSVAAVSTSVLGEHGIDKDVFLSLPCVLNANGVTSVVKQILTPTEVEQLQKSANIMSDVQAGLKF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: .*: . *::::* * **:*.*.*:: : ::.*: *:* .:::** :** *** * :*. ..*: .:***.: ::***.* ..*:** *:***. :* :.. : . ** :::*:****::**:.**:*.:* :**** ***::***:::.::**: . * :* ::*****:**.:*** *:*** *: *.. :*.. * *.* ** * .*:::.:****.*.*.:*. .: ::::* .::* * :*:..:::**:**:*. *: ..:: :. * : .*.. : :* : ", "identical_positions": 109, "similar_positions": 128, "identity": "28.39%" }, { "cls_id": "homologset.agr.FB:FBgn0001259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACE5-1", "uniprot_id": "INTU_RAT", "id": "D4ACE5-1", "name": "Protein inturned", "aln": "MADPARRDPRGRAPELPGDLSSQEEEEEESDSDAGASSLGSCSSASSD-TDLEPEWLDSVQRNGELFYLELSEDEEESLLPET--QTVNHVNHVRFSEKEVIIEEDDSRERK----KYEPKLRRFTKILKSKSLLPKRHHKKKSSNTGPVSILKHQSTQRTGVTVQQ-RYKDVTVYINPKKLTAIKAR--EQAKLLEVLVGVIHQTKWSWKRSGKQADGERLVVHGLVPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQVKLTFENAYAVKKETAQPKKKKAQSS-------------TNDLVKLLCGSEADATQHSTLSIPHITMYLTLQLQSEVAREEQEMLYHYPVSEASQKLKSVRGIFLTLCDMLESVTGTQVTSSSLHVNGKQIHVAYLKESDKLLLIGLPAEEVPLPQLRNMTEDVAQTLKFMYGSLDSAFCQVENTPRLDHFFSLFFERALRPGKLHLSASPSAQQYDAASAVLLDNLPG-VRWLLLPQELKVELDTALSDLEAADFQELSEDYYDMRRLYTILGSSLFYKGYMVCSHLPKDDVVEIAAYCRQYCLLPLAAQQ---RIGQLIIWREVFPQHHLQPATDSDPEAFQEPEGRYFLLIVGLRHYMLCVLLEAGGCASKATGNPG-PDCIYVDQARATLHQLEGVESRIEEQLAATPGPCLSCADWFLAAP-REKADSLTTSPILGRLQGPSKTAASPTCRRTFFSDY---SFKARKPSPSRIGGGREP-GEGEENVGLSPHTTPDTVRKQRESEGSD---DNVALLKLARKKSTLPNPFHLGTS---KKELSEKE-LEVYNMM--KLTSGPENTLFHYVALETVQGIFITPTHEEVAQLGGSVHSQLIKNFHRCCLTIRAVFQQTLKVEKKKALSDGDHLESANSVSSLSPVKEHGVLFECSPENWTDQKKTPPVMSYWVVGRLFLNPKPQELYVCFHDSVSEIAIEMAFRLFFGLTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q059U7-1", "uniprot_id": "INTU_MOUSE", "id": "Q059U7-1", "name": "Protein inturned", "aln": "MAGLARGDSRGRPPELPGDLSSQEEEEEEGDSDAGASSLGSYSSASSD-TDVEPEWLDSVQKNGELFYLELSEDEEESLLPET--QTANHVNHVRFSDKEVIIEEDDSRERK----KSEPKLRRFTKILKSKSLLPRRHHKKSSSNNGPVSILKHQSSQKTGVTVQQ-RYKDVTVYINPRKLTAIKAR--EQVKLLEVLVGIIHQTKRSWKRSAKQADGERLVVHGLLPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQVKLTFENAYAVKRETAQPQKKKAQSS-------------TQDLVKLLCGSEADAVQHSTLSIPHISMYLTLQLQSEAAREEQEILYHYPVSEASQKLKSVRGIFLTLCDMLESVTGTQVTSSSLHLNGKQIHVAYLKESDKLLLIGLPAEEVPLPQLRNMIEDVAQTLKFMYGSLDSAFCQVENAPRLDHFFSLFFERALRPGKLHLSGSPSAQQYAAASAVLLDNLPG-VRWLVLPQELKVELDTALSDLEAADFEELSEDYYDMRRLYTILGSSLFYKGYMVCSHLPKDDVIEIAAYCRQHCLLPLAAKQ---RIGQLIIWREVFPRHHLQPPSDSDPEAFQEPEGRYFLLVVGLRHYLLCVLLEAGGCASKATGNPG-PDCIYVDQVRATLHQLEGVDSRIEEQLATSPGPCLSCADWFLAAP-REKADSLTTSPILSRLQGPSKTAASPTCRRTFFSDY---SFKARKPSPSRIGGGREP-TEGEESAGLSPHATPDAVRKQRESEGSD---DNVALLKLARKKSTLPNPFHLGTS---KKELSEKE-LEVYDIM--KLTSGPENTLFHYVALETVQGIFITPTHEEVAQLGGSVHSQLIKNFHQCCLSIRAFFQQTLKEEKKKALSDGEHSEPTNSVSSLSPVKEHGVLFECSPENWTDQKKTPPVMSYWVVGRLFLNPKPQELYVCFHDSVSEIAIEMAFKLFFGLTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULD6-1", "uniprot_id": "INTU_HUMAN", "id": "Q9ULD6-1", "name": "Protein inturned", "aln": "MASVASCDSRPSSDELPGDPSSQEEDED-YDFEDRVSDSGSYSSASSDYDDLEPEWLDSVQKNGELFYLELSEDEEESLLPET--PTVN---HVRFSENEIIIEDD-YKERK----KYEPKLKQFTKILRRKRLLPKRCNKKNSNDNGPVSILKHQSNQKTGVIVQQ-RYKDVNVYVNPKKLTVIKAK--EQLKLLEVLVGIIHQTKWSWRRTGKQGDGERLVVHGLLPGGSAMKSGQVLIGDVLVAVNDVDVTTENIERVLSCIPGPMQVKLTFENAYDVKRETSHPRQKKTQSN-------------TSDLVKLLWGEEVEGIQQSGLNTPHIIMYLTLQLDSETSKEEQEILYHYPMSEASQKLKSVRGIFLTLCDMLENVTGTQVTSSSLLLNGKQIHVAYWKESDKLLLIGLPAEEVPLPRLRNMIENVIQTLKFMYGSLDSAFCQIENVPRLDHFFNLFFQRALQPAKLHSSASPSAQQYDASSAVLLDNLPG-VRWLTLPLEIKMELDMALSDLEAADFAELSEDYYDMRRLYTILGSSLFYKGYLICSHLPKDDLIDIAVYCRHYCLLPLAAKQ---RIGQLIIWREVFPQHHLRPLADSSTEVFPEPEGRYFLLVVGLKHYMLCVLLEAGGCASKAIGSPG-PDCVYVDQVKTTLHQLDGVDSRIDERLASSPVPCLSCADWFLTGS-REKTDSLTTSPILSRLQGTSKVATSPTCRRTLFGDY---SLKTRKPSPSCSSGGSDNGCEGGEDDGFSPHTTPDAVRKQRESQGSDGLEESGTLLKVTKKKSTLPNPFHLGNL---KKDLPEKE-LEIYNTV--KLTSGPENTLFHYVALETVQGIFITPTLEEVAQLSGSIHPQLIKNFHQCCLSIRAVFQQTLVEEKKKGLNSGDHSDSAKSVSSLNPVKEHGVLFECSPGNWTDQKKAPPVMAYWVVGRLFLHPKPQELYVCFHDSVTEIAIEIAFKLFFGLTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCN8-1", "uniprot_id": "INTU_DANRE", "id": "E7FCN8-1", "name": "Protein inturned", "aln": "MFSTCS-DGRP----------FQSFSTNLEDFDS-IRSVLLYS-------DLEPEWLDDVQKNGQLFYLELSDGEEEALLAQVSANHSAATNHVRFSEKEAEIITDNAKRQANSSNKSEAKLKKLTKILRRKRRPSQRKAEGKDSSQRPASILKNQAGQRPGVVVQQQRLKDVCVYLNPKRLSSVSSSSADRGGLLEALLGVVHRPGG---NTGKR--GGKLIIHGLIPHSPASKCAEILIGDALVAVDDVEVTSENIERVLSCIPGPMQVRLTLETVCPAG--VSPESKVSASPQ-------------VSQLVRLLWGEDTIELQMSIADVPHIAMFLSLRLDSETQQDEQEIVYQYPQSEASAQLKAVRGIFLTLCDMLENVTGGQIISSSLWLQQQLVHVGYWKEESNLLVIAVPASRVPLLYLQTVIEGVVRTLKVMYGSLDRGFSDVENAPRLDHFFCLFFQQLIQPSRLIHS----SRTPDLYGSLFLDGLPA-VRWLTLPPDIKVEVDTVLSDFESSDFGDMSEDFYGMRRLYVILGSCLFYKGYLIANHLPKEDLLDVCLYCQHYCLLPLASEQ---RVAQLVVWREVFPQRRETRNSTAHP-GYCQPHARHFLLIVGLRHFMQCVLLEAGGCASSAVGRPT-PDSVYVDQVKATLLQLESLDAGIEERLSAPPTPCLSCADWFLPAGGRSQQDTIGSSPILNRLTAAIKPPSPGGIGRSLFGEAGTVGIRGRRASPQRSQ--SDSGSEGHADGTPASVARRDSLG----SGGSDGSLGSAGFLKMPRLK--HPNPFYLGSL---RKSLSERETEEMQNVL--QVTAGVENTLFHYVLMESVQGIFIAPTHTEIRHLSGSIHPQLIHNFQHCCLSIRQAFQQSLPTRDRRGPE-------RQSTAGLGPVKEHGVLFQCKPQNWTDQKKPAPTMTYWVIGRMLLEPVPQEFYVCFHDSVAEVPVEMAFRLSFGLAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPH0-1", "uniprot_id": "INTU_DROME", "id": "Q9VPH0-1", "name": "Protein inturned", "aln": "----------------------MRKSPASLPSEAFSSSNSSLSNSYSD-GSDLANWEEYVSTDGSLFYMEYVRCEKTGVSAER---------RVEFMRRSLRLGKKSSRRQP--------------------HSNNQNQSQNQNQSHGPSRLDSQTEPQE----FRFSQFKTAAPDPKKLDLVITAADRFRFGRRSTAVESILG-----FRVLPFPDQPECLMVDGFVHDVSALQHG-IKRGDWFRSLNGIEVYASNVDELLKQFVEPTQVCLGFQSCGAASAVSPTDPGYNRNVREEQVCKVENFPMFTEKFEQMLITEGNFGIPGSSVDIRMPFAMLLLPPECYQHEQQQDSLYYFP-EIPDNFLFKARGSFLTLHAVLSELH-TQPLSSRLLVDQVQYHVNYRQLNGFLVLFAYAGGLCCAAECSLRSDELIGYIRFSLPGLVLESFNQEREPGNSSRLKLFLRHFCEIQRTRLVAR-------CHGHIRFEELLGQSRSLPLPKEAQLRIFDALSEMEAMDYRNWNDEPLTTHREFFIYGSALYYDGFLVASLLPPEVRVSVEGFLRCRGIFELLGAAPGIKVREMYVWEEIVLP---------------SATGRYFLTICTKNHLSLAVILKIFDAPDMAPDAVVGPSLFYIEEIQETLDHLVQCGIESLAMFWSVSNKRPEVLDATASES--RDQEKEPNNRLESFLKQKLTVLSPSVEEEAQLCSS----------------------LGGSSIHSLTPSEDESCRRRLTPIHGTAEDSDSGSDWENFAVQHPLHYGLNLGAESHSQSQMTESMWKEINNVVPVKISAGWKNSVLHYVYIDIANGSLFAPFTDSSENSNYLSEIRQACHIIHAVLQKSKHYRRHLSESSRAQTNS-----NGHSSHTVSLVKEHGMILEVSTQPKSDGQSQSSTSSRFVVVGRLFQSPAKEVYVCHRSDVPQNIVEMAFRLSFFSMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * . .:* : *. :*.***:* *: .: .: :*.* .. : . :.: :. : .... * : .: *. .: : * . : * : .: .:: *::.*:: .* : . : ** : :::.::* :.*::.:*. : * ** * ::. . . . . ...: ::* . * . * * :. .::*: :* :* . .. * .** **** :*..: * ** * :: ** * : .. *:::. .. : : ::. .* : *. * . : **:.: . : . : :: * . * * ** : ::.: .**::*: *: : .:: :* : * **.*:*.*:::.. ** : :.: : : :: * . :: :: :*.*:. .. .*:** : .* .*:*: .... * . *. .*::: : ** :* : : . . * . . :. .. : . * . :. .: : . * :. . *: . : : : ** :..:.* *: : : ::::* :*:::*** :: .:* :::* . : . . : :: :. * ::: * .: . :* :. *****:::: .. :* :. ... : :*: ::.. .:*.***.:..*.: :*:**:* * ", "identical_positions": 123, "similar_positions": 294, "identity": "12.5%" }, { "cls_id": "homologset.agr.FB:FBgn0001263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAD2-1", "uniprot_id": "INADL_RAT", "id": "F1MAD2-1", "name": "InaD-like protein", "aln": "----MPENPAAEKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLSHIPSDCSANFDFSRKGLLVFTDGSITNGNAHRPCSSITASESLPWTQRSGNEDFTSVIQQMAQGRHIEYIDIERPSTGGLGFSVVALRSQSLGLIDIFVKEVHPGSVADRDQRLKENDQILAINDTPLDQNISHQQAIALLQQATGSLRLVVAREVGHTQSRTSTSSADTTLPETVRWGHTEDVELINDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGSTNVQGMTSEQVAQVLRNCGNSVRMLVARDPVGEIAVTPPTP------ASLPVALPVVATRTLGSDSSP-FETYNVELVKKDGQSLGIRIV-GYVGTAHPGEASGIYVKSIIPGSAAYHNGQIQVNDKIVAVDGVNIQGFANQDVVEVLRNAGQVVHLTLVRRKTSLSASPFEQPSSREAVAEPPEVPEL--TGSLKPETNSRMEAEEIGERLDNLRKDTVQALEKPDVYPEDIPGCPENELKSRWENLLGPDYEVMVATLDTQIADDEELQKYSKLLPIHTLRLGMEVDSFDGHHYISSIAPGGPVDTLNLLQPEDELLEVNGVQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVD----------------------------------EPRTVEPSLLEAEVDRS--------------------VDVSTEDDD-GELALWSPEVKTVELVKDCKGLGFSILDYQDPLDPMRSVIVIRSLVADGVAERSGELLPGDRLVSVNEFSLDNATLAEAVEVLKAVPPGVVHLGICKPLVEEEKEEKEEHFIFHSNNNGDNSESPETVHEIHSSLILEAPQGFRDEPYL-EELVDEPFLDLGKSLQFQQKDMDSSSEAWEMHEFLSPRLERRGEEREMLVDEEYEIYQDRLRDMEAHPPPPHIREPTSASPRLDLQAGPQWLHADLSGGEILECHDTESMMTAYPQEMQDYSFSTTDMMKETFGLDSRPPMPSSEGNGQHGRFDDLEHLHSLVSHGLDLGMMTPSDLQGPGVLVDLPAVTQRREQEELPLYRLPSARVVTKPSSHVGMVSSRHANAACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTKALKTGDKILEVSGVDLQNASHAEAVEAIKSAGNPVVFVVQSLSSTPRVIPSVNNKGKTPPQNQDQNTQEKKAKRHGTAPPPMKLPPPYRAPS---ADTEESEEDSALTDKKIRQRYADLPGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPDGPAAADGRMRVGDELLEINNQILYGRSHQNASAIIKTAPTRVKLVFIRNEDAVNQMAVAPFPVPSHSPSPVEDLGGTEPVSSE---------------------EDSSVDAKPLPERESSKPEDLTQAVDDSMVAEQEKASESPDSAARQMKQPGYSAQVSSSSQEIPSAPAPLCQSTHADVTGSGNFQAPLSVDPAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLDA-IVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVIYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGEDVRQASQETVATILKCVQGLVQLEIGRLRAGSWASSRKTSQNSQGDQHSAHSSCRPSFAPVITSLQNLVG---TKRSSDPPQK--CTEEEPRTVEIIRELSDALGVSIAGGKGSPLGDIPIFIAMIQANGVAARTQKLKVGDRIVSINGQPLDGLSHTDAVNLLKNAFGRIILQVVADTNISAIATQLEMMSAGSQLGS-----PTADRHPQDPEELLQRTAD---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63ZW7-1", "uniprot_id": "INADL_MOUSE", "id": "Q63ZW7-1", "name": "InaD-like protein", "aln": "----MPENPAAEKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLSHIPSDCSANFDFSRKGLLVFTDGSITNGNAQRPCSNVTASELLPWTQKSASEDFNSVIQQMAQGRHVEYIDIERPSTGGLGFSVVALRSQSLGLIDIFVKEVHPGSVADRDHRLKENDQILAINDTPLDQNISHQQAIALLQQATGSLRLVVAREVGHTQGRASTSSADTTLPETVCWGHTEEVELINDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPVGEIAVTPPTP------VSLPVALPAVATRTLDSDRSP-FETYSVELVKKDGQSLGIRIV-GYVGTAHPGEASGIYVKSIIPGSAAYHNGQIQVNDKIVAVDGVNIQGFANQDVVEVLRNAGQVVHLTLVRRKTSLSASPFEHSSSRETVAEPPKVPER--AGSPKPEANLSVEAEEIGERLDNLKNNTVQALEKPDVYPEKVPGSPENELKSRWENLLGPDYEVMVATLDAQIADDEELQKYSKLLPIHTLRLGMEVDSFDGHHYISSVAPGGPVDTLNLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVD----------------------------------EPRTMEPALLEAEVDHS--------------------VDVNIEDDDDGELALWSPEVKTVELVKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERSGELLPGDRLVSVNEFSLDNATLAEAVEVLKAVPPGVVHLGICKPLVEDEKEER---FSLHSNNNGDSSEPADAVHEIHSSLILEAPQGFRDEPYL-EELVDEPFLDLGKSLQFQQKDVDSSSEAWEMHEFLSPPLDGRGEEREMLVDEEYELYQDHLRAMESNPPPPHIREAAPASPVLELQAGTQWLHANLSGGERLECHDAESMMSAYPQEMQQYSYSTADMMEETFGLDSRAPIPSSEGNGQHGRFDDMGHLHSLTSSSLDLGMMIPSDLQGPGVLVDLPAVAQRREQEDLPLYRLPSARVVTKPSSHMGLVSSRHANAACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHAEAVEAIKSAGNPVVFVVQSLSSTPRVIPTVNNKGKTPAPNQDQNTQERKAKRHGTAPPPMKLPPPYRAPS---ADMEGSEEDCALTDKKIRQRYADLPGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASAIIKTAPTRVKLVFIRNEDAVSQMAVAPFPELSHSPSPVEDLGGTELVSSE---------------------EESSVDAKHLPEPESSKPEDLSQVVDDNMVAEQQKESESPDSAACQIKQQTYSTQVSSSSQDSPSSPAPLCQSAHADVTGSGNFQAPLPVDPAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLDA-IVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVVYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGEDMRHASQETVATILKCVQGLVQLEIGRLRAGSWAASRKTSQNSQGDQHSAHSSCRPSFAPVITSLQNLVG---TKRSSDPPQK--CTEEEPRTVEIIRELSDALGISIAGGKGSPLGDIPIFIAMIQANGVAARTQKLKVGDRIVSINGQPLDGLSHTDAVNLLKNAFGRIILQVVADTNISAIATQLEIMSAGSQLGS-----PTADRHPEDTEEQMQRTAD---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NI35-1", "uniprot_id": "INADL_HUMAN", "id": "Q8NI35-1", "name": "InaD-like protein", "aln": "----MPENPATDKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLNHIPSDCSANFDFSRKGLLVFTDGSITNGNVHRPSNNSTVSGLFPWTPKLGNEDFNSVIQQMAQGRQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIFVKDVQPGSVADRDQRLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVAREPVHTKSSTSSSLNDTTLPETVCWGHVEEVELINDGSGLGFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPAGDISVTPPAP------AALPVALPTVASKGPGSDSSL-FETYNVELVRKDGQSLGIRIV-GYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHLTLVRRKTSSSTSPLEPPSDRGTVVEPLKPPALFLTGAVETETNVDGEDEEIKERIDTLKNDNIQALEK----LEKVPDSPENELKSRWENLLGPDYEVMVATLDTQIADDAELQKYSKLLPIHTLRLGVEVDSFDGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVD----------------------------------EPRRTETSLPETEVDHN--------------------MDVNTEEDDDGELALWSPEVKIVELVKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAVPPGLVHLGICKPLVEDNEEES--CYILHSSSNEDKTEFSGTIHDINSSLILEAPKGFRDEPYFKEELVDEPFLDLGKSFHSQQKEIEQSKEAWEMHEFLTPRLQEMDEEREILVDEEYELYQDPSPSMELYP-LSHIQEATPVPSVNELHFGTQWLHDNEPS----ESQEARTGRTVYSQEAQPYGYCPENVMKENFVMESLPSVPSTEGNSQQGRFDDLENLNSLAKTSLDLG-MIPNDVQGPSLLIDLPVVAQRREQEDLPLYQHQATRVISKASAYTGMLSSRYATDTCELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPRVIPNVHNKANKITGNQNQDTQEKKEKRQGTAPPPMKLPPPYKALT---DDSDENEEEDAFTDQKIRQRYADLPGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSE---------------------EDGSVEVG----------------------IKQLPESESFKLAVSQMKQQKYPTKVSFSSQEIPLAPASSYHSTDADFTGYGGFQA-------PLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLNA-IVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVATILKCAQGLVQLEIGRLRAGSWTSARTTSQNSQGSQQSAHSSCHPSFAPVITGLQNLVG---TKRVSDPSQKNSGTDMEPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNISAIAAQLENMSTGYHLGS-----PTAEHHPEDTEEQLQMTAD---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8K6-1", "uniprot_id": "A0A8M2B8K6_DANRE", "id": "A0A8M2B8K6-1", "name": "", "aln": "MYENVPTVSASERQQVLQALERLQSKLVQREEWTHSDRLGTLKEALQSPLFSHILTLQHSVKQLKDQLNSLPPDTCSEFSFSRKGQLIVSASRPSSSLGSVLSNGTALTN-------ASSEQLQRWIQAAAKGRKTELISLQKPLSGGLGFSVVGLRPEGVGGHGVFVRQVQPGSVADRDGRLLENDQILAINGIPLDQSVTQQQAIALLQQQKDRVELVVARDTALKPRLSASAPITTDQ-----WGHVEEIELVNDGSGLGFGIVGGKTTGMVVRTVVPGSVADKDGRLRTGDHILRIGDTMTRGLASDQVVQVLQACGAHVRMLIAREPLGAKQPAPPPAPAMGPVSSLPPPPPVPARRASRTPNLEGFEIHEVALK-KEGQSLGISII-GHN-ALTSEDAVGVYVKNVIPGSIAEQTGKIQIHDRIISLDGVNLQGYNNQEVLEVMKQSGDVVHLTLVRKIISPKRTTMEKSLDKVQRESS--------RVSLKRSSEMKARADQRGSVVESIDPALSGIKQQLQANMQEPASLTEMELRAKWEQALGPHYDVMIVQLDPVIEDDIELQKYSKLLPIHTMRLGVELDSFDGHHYISTVAPEGPVAKHGLLRPEDELLEVNGVQLYGKSRRESVAFLREVPTPFTLVCCRRLAKEDNEYHPESEDWHSYSLQEQIEHNLSMLARDTSLRDSIREEFQARQASAVEREVDDEGEPLEPISPEKEQMDQENDDDDEEEEEEDEGELALWSPNVQVLELEKAERGLGFSILDYQDPMDVARSVIVIRSLVPGGVADNHGGIFPGDQLVFVNDTHLETCSLAQAVEVLKSAPPGKVYLGIRKPLAAEDRGSG-----QQSLWPVESVDEQPTAKQAVSHTLPPMPEDFVNGSILSDDLDEEPELILDAEPRYASP--------------LTTVDLQPDVEKEMAVDEE--------------------EEDVDVNVMEDQQS----------------SKVNDTSLPSYLSEKIRS--WEEPATSSRYHLNTEPDLQEQVDDDLSMNLEKIQLQPLKIPLGHFTSWVETADSDS----------DSRNEGSELTLTDTDNE-SAQRTSSRNRKRRNQAGPTRGDLPEREEGEGEETPVFSHWGPPRRVEVWAEPEESLGISIVGGRTVIKRLKNGEELKGIFIKQVLADSPAGRTGALKTGDKILQVSGVDLQNASHEEAVQTIKAAPSPVVFIVQSLSSTPRPVSVT---ASSIKQHKAKRKAAQKAG-QGAAPPPMRLPPPYRPPSQVQEEEQEQEEEDEQDTEVIRQRYADLPGELLIVELEKDRNGLGLSLAGNRDRSCMSIFVVGITTGGPASRDGRIKVGDELLEINNQVLYGRSHQNASAIIKSAASKVKLVLVRNEDAINQMAVTPFPSQPALFSSSETHENPPAVPAEKPQLPESLPLSRSPPENTLNKDQACVTATASSDPTHKSLTDGESAVKKLKPAEKLLESPSEQSAKPQVEQIPSLPKLQRSS-TKPSTGSLEVTSSASSVPVSGTSPD-----FEYCSKDPATCPIVPGQETVIEISKGRSGLGLSIVGGKDTQLDA-IVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSVAHEDAIAALRQTPPKVRLTVLRDEAQYRDEENLDVFPVELQKKTGRGLGLSIVGKRNGKGVFISDVVKGGAADLDGRLMQGDQILSVDGEDMRQASQETVAAILKCARGKVLLELGRLKAASWISSRRTSQGSQMSHASASSSTPTPTPPTVAPPPSQTPNNNSRNIAEPISKSTVTEPGVRTVEITRGPTDALGISIAGGKGSPLGDIPIFIAMIQANGVAAKTHRLKVGDRIVSINSQSLDGLTHADVVNMLKNAYGAIILQVVADTNISAIASQVESLSSSSAPSTNPEVRLVEPETPKPKSITLEKGSEGLGFSIVGGFGSPHGDLPIYVKTVFGKGAAAVDGRLKRGDQLLSVNGESLEGVTHEQAVAILKKQRGSVTLSVLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24008-1", "uniprot_id": "INAD_DROME", "id": "Q24008-1", "name": "Inactivation-no-after-potential D protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQFLGKQGTAGELIHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNGKDVRNSTEQAVIDLIKEAD---------------------------------------------------------------------------------------------------------------------------------FKIELEIQTFD---------------------------------------KSDEQQAKSDPRSNGYMQAKNKFNQEQTTN------------------------------------------------------------------------NNASGGQGMGQ--------------GQGQGQGMAGMNRQQSMQKRNTTFTAS--------------MRQKHSNYADEDDEDTRDMTGRIRTEAGYEIDRASAGNCKLNKQEKDRDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQEDEFGYTMAKINKR------------------------------------------------------------------------------------YNMMKDLRRIEVQRDASKPLGLALAG--------HKDRQKMACFVAGVDPNGALG-SVDIKPGDEIVEVNGNVLKNRCHLNASAVFKNVDGDKLVMITSR---------------------------RKPNDEGMCVKPIKKFP--------------------TASDETKFIFDQFP-KARTVQVRKEGFLGIMVIYGKHAEVGSGIFISDLREGSNAELAG-VKVGDMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLK--------------------------------------------------------------------------------------------SEEAIKAEKAAEEKKKEEAKKEEEKPQ--------------------------------EPATAEIKPNKKILIELKVEKKPMGVIVCGGKNNHVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPIHVG--SMTTLKVHQLFHTTYEKAVTLTVFRADPPELEKFNVDLMKKAGKELGLSLS--PNEIGCTIADLIQGQYPEIDSKLQRGDIITKFNGDALEGLPFQVCYALFKGANGKVSMEVTRPKPTLRTEAPKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * * . :*:** *: * .: *:::*.::*.* * *:::: *:*::::* :::. :: *:::::::. ::: :*:::** :. :. * . : .:. .:: . : :. *: :* *:: :: *:.:: .:.:. : .: .:: :. :: :. . . . * * :. . : : .: :. * :*: :.. .**:::.* ::..: . *: * :.. * : :*.**:*::*.* *:* .* :* .:* . . :.:: * :* .* . *:: * . : : ::* : :::.*: : : *:: . .**: .: . * * :::** ** :*::: .:::*:.::* * *.:::: : * . : : .. * :***. * *.:: :**:. :. :*: : ***:. : : ** .** ** .* * ** *:* ::**. :: . : ::* .. . * :*: * *:* **:*: ****: . * *:*:::* .::*.:* :** * ..:*: :. . :. :::* ..* * :*: * :. : : ", "identical_positions": 122, "similar_positions": 260, "identity": "6.05%" }, { "cls_id": "homologset.agr.FB:FBgn0001269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8B1-1", "uniprot_id": "D3Z8B1_RAT", "id": "D3Z8B1-1", "name": "Homeobox protein engrailed-like", "aln": "----------------------------------------------------------MEEKDSKSSE----------TAA--EAQRQPEPSPGGGSGGG--SSPSDSDTGRRR-------------------------------------ALMLPAVLQAPGNH----QHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGARGG----EGGAGSTEGGGG--------------------------ADGAEQILG--ARESRPN-----------------------------PACAPSAGGPLSGASGDPAADGEGGSKT-------------------------------LSLHGGAKKPGDPGGSLDGALKA-RGLGGGDLSVSS-------DSDSSQASATLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09066-1", "uniprot_id": "HME2_MOUSE", "id": "P09066-1", "name": "Homeobox protein engrailed-2", "aln": "----------------------------------------------------------MEEKDSKPSE----------TAA--EAQRQPEPSSGGGSGGG--SSPSDSDTGRRR-------------------------------------ALMLPEVLQAPGNH----QHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGARGG----EGGAGTTEGGGGG-------------------------AGGAEQLLG--ARESRPN-----------------------------PACAPSAGGTLSAAAGDPAVDGEGGSKT-------------------------------LSLHGGAKKPGDPGGSLDGVLKA-RGLGGGDLSVSS-------DSDSSQASATLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19622-1", "uniprot_id": "HME2_HUMAN", "id": "P19622-1", "name": "Homeobox protein engrailed-2", "aln": "----------------------------------------------------------MEENDPKPGE----------AAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRR-------------------------------------ALMLPAVLQAPGNH----QHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGG--------------------------AGGSEQLLGSGSREPRQN-----------------------------PPCAPGAGGPLPAAGSDSPGDGEGGSKT-------------------------------LSLHGGAKKGGDPGGPLDGSLKA-RGLGGGDLSVSS-------DSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKNPNK----------------------EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31533-1", "uniprot_id": "HME2B_DANRE", "id": "P31533-1", "name": "Homeobox protein engrailed-2b", "aln": "----------------------------------------------------------MEENDHSNR----------------DVERQ------------------DSGDESNR-------------------------------------AILP--LLQAPGN-----VLPHRITNFYIDNILRPDFGRRK--------EGSRRDE-------INIVE------------------------------------------RENR----------------------------------CPSAPG----SGQVAPVSGEGTSSP-------------------------------RAVN--ASKKTDIS--TDESLKS-RAETG-DQCLSS-------DSDCSQRCAAQAKQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKTPTK----------------------EDKRPRTAFTAEQLQRLKNEFQNNRYLTEQRRQALAQELGLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHATVTKDDKSDSD----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JT82-1", "uniprot_id": "A0A0G2JT82_RAT", "id": "A0A0G2JT82-1", "name": "Homeobox protein engrailed-like", "aln": "----------------------------------------------------------MEEQQPEPKSQRDSGLGAVAAAAAVVAAAAPGGLSLSLSPGASGSSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPHLPPHPPPPPPPP--PPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPLPQLLVASAAAGGGAAGGGSRVERDRSQT-------------------------GAGRDPVHSLGTRASGAAS----------------------------LLCAPDANCGPPDGSQPATAVGAGASKAGNP-------------AAAAAAAAAAAAAAVAAAAAAASKPSDSGGGSGGSAGS-PGAQGAKFPEHNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSG--PRTRKLKKKKNEK----------------------EDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05527-1", "uniprot_id": "HMIN_DROME", "id": "P05527-1", "name": "Homeobox protein invected", "aln": "MSTLASTRPPPLKLTIPSLEEAEDHAQERRAGGGGQEVGKMHPDCLPLPLVQPGNSPQVREEEEDEQTECEEQLNIEDEEVEEEHDLDLEDPASCCSENSVLSVGQEQSEAAQAALSAQAQARQRLLISQIYRPSAFSSTATTVLPPSEGPPFSPEDLLQLPPSTGTFQEEFLRKSQLYAEELMKQQMHLMAAARVNALTAAAAGKQLQMAMAAAAVATVPSGQDALAQLTATALGLGPGGAVHPHQQLLLQRDQVHHHHHMQNHLNNNENLHERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEELQELQEAASAAAAKEPC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*:: . : . . * * * :::: ::::: :: .. . . .. . . * :. : ..: * . : . . :. . . *::***************** **:** ** . *********:. ** *** **: ***:**:*** *: **.***:************:**::* ** **::*********:* . :.:. ", "identical_positions": 89, "similar_positions": 64, "identity": "15.45%" }, { "cls_id": "homologset.agr.FB:FBgn0001276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NX70-1", "uniprot_id": "MED29_HUMAN", "id": "Q9NX70-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "---MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSS----DGPIQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDS--LPYPQYLAVIKAQISCAKDIHTALLDCANKVTGKTPAPPAGPGGTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB91-1", "uniprot_id": "MED29_MOUSE", "id": "Q9DB91-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "---MAAPQPQAAAVSSASGVSGPGSAGGPGPQQQPQP-TQLVGSAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSS----DAPLQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDS--LPYPQYLAVIKAQITCAKDIHTALLDCANKVTGKTTAPSTGPGGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JHI6-1", "uniprot_id": "MED29_DANRE", "id": "Q8JHI6-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "----MASQQMSTNNAQMS-------AQQAAVLQQTQA-QQLS----------QQQDFDPVHRFKMLIPPLKDSLQNVMTIASLNFAHNTAIDNGLKTTEKGNDAAVQRFDKSLEEFYALCDQLELCLRLAHECLSQSIDSTKHSPNLVPTATKPDTVQTES--LSYSQYLSMIKSQISCAKDIHNALLECSKKIAGK------GQGACN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KBL8-1", "uniprot_id": "MED29_DROME", "id": "Q7KBL8-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "MNPNMNMMPMSGPQMMQVMQSSPSGPPGPVQHQQQQPPQPLQQ-------QQQAEKLDNISRVKSLLGPLRESMFLTIRSSAFALQQNNLADNLKRDTG---AHHVPRFDKHLEDFYACCDQIEIHLKTAMQCLQQQNSSNHYLPGPVTPMRMETFMPDNAGPISYPTYLNTVRVHIQSAKDIHDTLISAAQNISQAD-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . ** *. * * :.:* : * * *: *::*: : :: : :*. ** : : : **** **:*** ***:*: *: * :**.*. .* :: * *.. : :: :.*. ** :: :* .***** :*:..::::: ", "identical_positions": 45, "similar_positions": 52, "identity": "21.53%" }, { "cls_id": "homologset.agr.FB:FBgn0001280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NRX4-1", "uniprot_id": "PHP14_HUMAN", "id": "Q9NRX4-1", "name": "14 kDa phosphohistidine phosphatase", "aln": "----------------MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DAK9-1", "uniprot_id": "PHP14_MOUSE", "id": "Q9DAK9-1", "name": "14 kDa phosphohistidine phosphatase", "aln": "-----------------MAADLGQIPDVDIDSDGVFKYVLIRVHLAEPSGDPAKECKEIVRGYKWAEYHADIYDKVSGELQRNGYDCECLGGGRISHQSQDRKIHVYGYSMGYGRAQHSVSTEKIKAKYPDYEVTWADDGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20348-1", "uniprot_id": "JANA_DROME", "id": "P20348-1", "name": "Sex-regulated protein janus-A", "aln": "MNRLQLLSKGLRLIHKMSEEALAGVPLVHISPEGIFKYVMINVFDG---GD---ASKAVIRGFADCTWHADIFEREEEVFKKLGLRAECPGGGRIEHNPEKKYLKVYGYSQGFGKADHAQTKRILATKYPDYTIEISDEGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :* *.*..:*:****:*.*. . * .* ::**: . :****::: . ::: * .** *****.*:.:.: ::***** .:* *:*: :.. : :***** : :::**", "identical_positions": 43, "similar_positions": 46, "identity": "30.5%" }, { "cls_id": "homologset.agr.FB:FBgn0001281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NRX4-1", "uniprot_id": "PHP14_HUMAN", "id": "Q9NRX4-1", "name": "14 kDa phosphohistidine phosphatase", "aln": "-MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVR---GYKWAEY------------HADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAK--YPDYEVTWANDGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DAK9-1", "uniprot_id": "PHP14_MOUSE", "id": "Q9DAK9-1", "name": "14 kDa phosphohistidine phosphatase", "aln": "--MAADLGQIPDVDIDSDGVFKYVLIRVHLAEPSGDPAKECKEIVR---GYKWAEY------------HADIYDKVSGELQRNGYDCECLGGGRISHQSQDRKIHVYGYSMGYGRAQHSVSTEKIKAK--YPDYEVTWADDGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20349-1", "uniprot_id": "JANB_DROME", "id": "P20349-1", "name": "Sex-regulated protein janus-B", "aln": "MKMFKSLRLLPHIVSPFQKCYSTDLISLVGVPRVKITKGQNRYLLVNIHTHGFTKYGRVIVRGADVDNHLAVFDSILEELEPEGICAKILGGGRILNEAENKKIKIYGTSRTFGGADHTRTRNILQAWTTYKDFKITVKQ---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :*.: : :. ** : . . : : :: : :::* * ::*.: ::: :* .: ****** ::::::**::** * :* *:*: : : ::* * *:::* : ", "identical_positions": 26, "similar_positions": 47, "identity": "18.18%" }, { "cls_id": "homologset.agr.FB:FBgn0001291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17325-1", "uniprot_id": "JUN_RAT", "id": "P17325-1", "name": "Transcription factor Jun", "aln": "MTAKMETTFYDDALNASFLQSES---------GAYGYSNP---------------KILKQSMTLNLADP-VGNLKP-------HLRAKNSD--------LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPT----QFLCPKN-------------VTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVSGAG------MVAPAVASVAGAGGGGGYSASLHSEPPVYANLSNFNPGALSSGGGAPSYGATGLAFPSQPQQQQQPPQPPHHLPQQIPVQHPR-LQALKEEPQTVPEMP-------GETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05627-1", "uniprot_id": "JUN_MOUSE", "id": "P05627-1", "name": "Transcription factor Jun", "aln": "MTAKMETTFYDDALNASFLQSES---------GAYGYSNP---------------KILKQSMTLNLADP-VGSLKP-------HLRAKNSD--------LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPT----QFLCPKN-------------VTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVSGAG------MVAPAVASVAGAGGGGGYSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPSQPQQQQQPPQPPHHLPQQIPVQHPR-LQALKEEPQTVPEMP-------GETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05412-1", "uniprot_id": "JUN_HUMAN", "id": "P05412-1", "name": "Transcription factor Jun", "aln": "MTAKMETTFYDDALNASFLPSES---------GPYGYSNP---------------KILKQSMTLNLADP-VGSLKP-------HLRAKNSD--------LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPT----QFLCPKN-------------VTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAG------MVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPP---HHLPQQMPVQHPR-LQALKEEPQTVPEMP-------GETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52909-1", "uniprot_id": "JUND_RAT", "id": "P52909-1", "name": "Transcription factor JunD", "aln": "----METPFYGEEALSGLAAGASSVAGAAGAPGGGGFAPPGRAFPGAPPTS---SMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAP------DGLLASPDLGLLKLASPELERLIIQS-NGLVTTTPTST----QFLYPKV-------------AASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAP----------PAPADLAATPG--------ATETPVYANLSSF------AGGAGPPGGAATVAFAAEPVPFPPPPG---ALGPPPPPHPPR-LAALKDEPQTVPDVPS-----FGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15066-1", "uniprot_id": "JUND_MOUSE", "id": "P15066-1", "name": "Transcription factor JunD", "aln": "----METPFYGEEALSGLAAGASSVAGATGAPGGGGFAPPGRAFPGAPPTS---SMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAP------DGLLASPDLGLLKLASPELERLIIQS-NGLVTTTPTST----QFLYPKV-------------AASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAP----------PAPADLAATPG--------ATETPVYANLSSF------AGGAGPPGGAATVAFAAEPVPFPPPPG---ALGPPPPPHPPR-LAALKDEPQTVPDVPS-----FGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17535-1", "uniprot_id": "JUND_HUMAN", "id": "P17535-1", "name": "Transcription factor JunD", "aln": "----METPFYGDEALSGLGGGAS------GS--GGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAAALKPAAAPPPTPLRADGAPSAAP-PDGLLASPDLGLLKLASPELERLIIQS-NGLVTTTPTSS----QFLYPKV-------------AASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPGELAPAAA--------APEAPVYANLSSY------AGGAGGAGGAATVAFAAEPVPFPPPP-------PPGALGPPR-LAALKDEPQTVPDVPS-----FGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LGL0-1", "uniprot_id": "A0ABK0LGL0_RAT", "id": "A0ABK0LGL0-1", "name": "Transcription factor JunB", "aln": "MCTKMEQPFYHDDSYAAAGYGRS----------PGSLSLHD-------------YKLLKPTLALNLADP-YRGLKGPGARGPGPEGSGAGS-----YFSGQGSDTGASLKLASTELERLIVPNSNGVITTTPTPPG---QYFYPRGGGSGGGTG---GGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGASGGPQ---------AGPGGVYAGPE----------PPPVYTNLSSYSPASAPSGGSGTAVGTGSSYPTATISYLPHAPP--FAGGHPAQLGLSRGASAFKEEPQTVPEARS-----RDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09450-1", "uniprot_id": "JUNB_MOUSE", "id": "P09450-1", "name": "Transcription factor JunB", "aln": "MCTKMEQPFYHDDSYAAAGYGRS----------PGSLSLHD-------------YKLLKPTLALNLADP-YRGLKGPGARGPGPEGSGAGS-----YFSGQGSDTGASLKLASTELERLIVPNSNGVITTTPTPPG---QYFYPRGGGSGGGTG---GGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGASGGPQ---------AGPGGVYAGPE----------PPPVYTNLSSYSPASAPSGGSGTAVGTGSSYPTATISYLPHAPP--FAGGHPAQLGLSRGASAFKEEPQTVPEARS-----RDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSAAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17275-1", "uniprot_id": "JUNB_HUMAN", "id": "P17275-1", "name": "Transcription factor JunB", "aln": "MCTKMEQPFYHDDSYTATGYGRA----------PGGLSLHD-------------YKLLKPSLAVNLADP-YRSLKAPGARGPGPEGGGGGS-----YFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPG---QYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPP---------AGPGGVYAGPE----------PPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPP--FAGGHPAQLGLGRGASTFKEEPQTVPEARS-----RDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABU6-1", "uniprot_id": "A0AB13ABU6_DANRE", "id": "A0AB13ABU6-1", "name": "", "aln": "MTGKMETPFYHDESVPNFGQVPEY----------DRYQSHK--------------MMKKSSAGHSFPGGGGAGLKLLQGPAGSGVGGSSGVGMSSSTGSLMPTADINLLKLSSPDLEHLIIQSNQGLVTTSPAPGGSANPFLYRNQ-------------ATNEQEGFADGFVKALADLHKQNQLLAPPSPTPAPLQSS----------YQRSLMPSAD-----------MPIYTTLSSYTP---------SPYPAGQLYPHTSAHATGLHPQ-----------------SRGPDAPQTVPEVPHPPGDPCSSPPALSPIDLETQERIKAERKKLRNRIAASKCRKRKLERISRLEEKVKVLKTQNSDLASTAGILREQVAQLKQKVMNHVTSGCQISVSSASMGKGGDSGC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18289-1", "uniprot_id": "JRA_DROME", "id": "P18289-1", "name": "Transcription factor Jra", "aln": "----MKTPVSAAANLSIQNAGSS---------GATAIQIIPKTEPVG--------EEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSN---NLMQTPQPGK---VFPTKAG------------PVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANN----------TTAAAMTAVN--------------------------------NGISGGTFTYTNMTEG----------------------FSVIKDEPVNQASS-----------PTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQ--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .. . : . . : . : .: :.:**:::: . : :* . : .: *: *. ** .** :**. . . . : * . .. *.:.**::: **:** ***: ***:**:**********::**::**.** :* *:* . *:::******:*: *: ** : ", "identical_positions": 58, "similar_positions": 63, "identity": "14.11%" }, { "cls_id": "homologset.agr.FB:FBgn0001297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUR3-1", "uniprot_id": "A0ABK0LUR3_RAT", "id": "A0ABK0LUR3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRDFGEPG--------PSSGAGSAYGRPAQPQQAQTQTV----QQQ---------FHLVPSINAVSGSQELQWMVQPHFLGP------------------------------------------------------------------------------------------SGYPRPLTY-PQYS-PPQP------RPGVIRALGPPPGV---------------------RRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEE------------------------DKKDTGGTSSTSG---------AGSP---------------PGPCR----------------------------PVPCISLSPGP------------VLEPEALHTPTLMT-----TPSLTPFTPSLVFTYPST--------------------PEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48755-1", "uniprot_id": "FOSL1_MOUSE", "id": "P48755-1", "name": "Fos-related antigen 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYRDYGEPG--------PSSGAGSPYGRPAQPPQAQAQTA----QQQK--------FHLVPSID--SSSQELHWMVQPHFLGP------------------------------------------------------------------------------------------TGYPRPLAY-PQYS-PPQP------RPGVIRALGPPPGV---------------------RRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEG------------------------DKKDPGGSGSTSG---------ASSP---------------PAPGR----------------------------PVPCISLSPGP------------VLEPEALHTPTLMT-----TPSLTPFTPSLVFTYPST--------------------PEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15407-1", "uniprot_id": "FOSL1_HUMAN", "id": "P15407-1", "name": "Fos-related antigen 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRDFGEPG--------PSSGNGGGYGGPAQPP-AAAQAA----QQK---------FHLVPSINTMSGSQELQWMVQPHFLGP------------------------------------------------------------------------------------------SSYPRPLTY-PQYS-PPQP------RPGVIRALGPPPGV---------------------RRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEG------------------------AKE--GDTGSTSG---------TSSP---------------PAPCR----------------------------PVPCISLSPGP------------VLEPEALHTPTLMT-----TPSLTPFTPSLVFTYPST--------------------PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHY8-1", "uniprot_id": "A0A8M3AHY8_DANRE", "id": "A0A8M3AHY8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MY-NYGNPGRGID-RSFPESSSGSSGSSSASVATTTGTTQ----QQQQKYSVAGS-GQFVPSLNAITSNQSLQWMLQPSIGTPGPS-----------------------------------------------------------------------------------RALRSSYPLPPGI-PATMNPPQPSQSHLSRPGVIRAAAAIGST---------------------TRRNDEYLSPEELERRRIRRERNKMAAAKCRNRRRELTDTLQNETDQLEDEKSRLQKEIADLQKEKEKLELVFEAHRPICKVQESE----------------------SDSDSSNDIPSLSG---------IKIEP---------VDPDLPGPSRE------------------TKHYAKINKPKPKITIPPPPSASSIT----GIPLESESLHTPVLIS-----TPSLTPFTASLVFSYPSTSLDTSSQALNLVTSHPSSQNPQPCAVAHRRSSSS-GDQSDHSLNSPTILTL---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51145-1", "uniprot_id": "FOSL2_RAT", "id": "P51145-1", "name": "Fos-related antigen 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQDYPG--------NFDTSSRGSSGSPAHAESYSSGGGG----QQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITS----------------------------------------------------------------------------------------MSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGR---------------------RRR-DEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEE----------------------RRSPPTSGLQSLRGTGSAVGPVVVKQEP---------PEEDSPSSS--------------------AGMDKTQRSVIKPISIAGGG------------FYGEEPLHTPIVVTS----TPAITPGTSNLVFTYPSVLEQESP-----------ASPSESCSKAHRRSSSS-GDQSSDSLNSPTLLAL---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47930-1", "uniprot_id": "FOSL2_MOUSE", "id": "P47930-1", "name": "Fos-related antigen 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQDYPG--------NFDTSSRGSSGSPAHAESYSSGGGG----QQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITS----------------------------------------------------------------------------------------MSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGR---------------------RRR-DEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEE----------------------RRSPPTSGLQSLRGTGSAVGPVVVKQEP---------PEEDSPSSS--------------------AGMDKTQRSVIKPISIAGGG------------FYGEEPLHTPIVVTS----TPAITPGTSNLVFTYPNVLEQESP-----------SSPSESCSKAHRRSSSS-GDQSSDSLNSPTLLAL---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15408-1", "uniprot_id": "FOSL2_HUMAN", "id": "P15408-1", "name": "Fos-related antigen 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYQDYPG--------NFDTSSRGSSGSPAHAESYSSGGGG----QQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITS----------------------------------------------------------------------------------------MSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGR---------------------RRR-DEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEE----------------------RRSPPAPGLQPMRSGGGSVGAVVVKQEP---------LEEDSPSSSS-------------------AGLDKAQRSVIKPISIAGG-------------FYGEEPLHTPIVVTS----TPAVTPGTSNLVFTYPSVLEQESP-----------ASPSESCSKAHRRSSSS-GDQSSDSLNSPTLLAL---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12841-1", "uniprot_id": "FOS_RAT", "id": "P12841-1", "name": "Protein c-Fos", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSS--------------------------------------------------------------------------------------------VAPSQTRAPHPYGLPTPSTGAYARAGVVKTMSGGRAQSIG------------------RRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPNDLGFPEEMSVTSLDLTGGLPEATTPESEEAFTLPLLNDPEPKPSLEPVKNISNMELKAEPFDDFLFPASSRPSGSETARSVPDV---DLSGSFYAADWEPLHSSSLGMGP-----------MVTELEPLCTPVVTC-----TPSCTTYTSSFVFTYPEADS------------------FPSCAAAHRKGSSS-NEPSSDSLSSPTLLAL---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01101-1", "uniprot_id": "FOS_MOUSE", "id": "P01101-1", "name": "Protein c-Fos", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSS--------------------------------------------------------------------------------------------VAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRAQSIG------------------RRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFTLPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPDV---DLSGSFYAADWEPLHSNSLGMGP-----------MVTELEPLCTPVVTC-----TPGCTTYTSSFVFTYPEADS------------------FPSCAAAHRKGSSS-NEPSSDSLSSPTLLAL---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01100-1", "uniprot_id": "FOS_HUMAN", "id": "P01100-1", "name": "Protein c-Fos", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSS--------------------------------------------------------------------------------------------VAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIG------------------RRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDM---DLSGSFYAADWEPLHSGSLGMGP-----------MATELEPLCTPVVTC-----TPSCTAYTSSFVFTYPEADS------------------FPSCAAAHRKGSSS-NEPSSDSLSSPTLLAL---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P0S1-1", "uniprot_id": "A0A8M9P0S1_DANRE", "id": "A0A8M9P0S1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQLFIEKNKP--------IEESPQRLCVSIDVRDNAKRNLLCPSRSQGESP-------GAFVPTVTAISSTPDLQWMVQPTIITS--------------------------------------------------------------------------------------------VSPSQGRTDSNE------------PAKSKPAGN-KGKCAA------------------RKSKSEQLSPEEEEKKRIRRERNKMAAAKCRNRRRELTDTLQAETDKLEEDKAALQAEIESLLKEKERLEYVLASHKPLCQMPEELDCLFPESPQPLPAPESSSKLPEDSPQDAASLQDLEIPTVPSSAISGNSNILLCSSAEVSLCDLEPSLDVRDELLAGSG----------GDDDRVSARSVPDIDLSGSLGITDWETLYKSVANDLEPLSTPVVSTS----TPTCSNYLSVFTFACPELDS-------------------LAEGLDVCKCGVTKAESSVDILNSPTLLAL---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21525-5", "uniprot_id": "FOSLA_DROME", "id": "P21525-5", "name": "Transcription factor kayak, isoforms A/B/F", "aln": "MKNLNGRTHNACYHPYYHQSLHFAQQQQQQQQHHLQQQQQHMQQQQQQQQAPQQQLRHQQRQLPTQPAYQQSQSVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNNAAAMAAVCQMQNFFNQQQQQQQQLEFNNNCMPINYYQQQQQQHYPSESQSSASGWNPETPGQAQLALTATTCNTTAAATCNTTAAATTSTTATSAAAGSDNNHSDNFAMDASEIATFLANELFLQQLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAG--LLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMP---------HVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSIN--------------NINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : .: : * . . . . . . ::*** ::: :****** ***:**:** : *: * *.::**. :: ** * :.*::** :: :* . *: *. : ..: ** ** : : : * . . : . *. *:: ", "identical_positions": 38, "similar_positions": 54, "identity": "4.87%" }, { "cls_id": "homologset.agr.FB:FBgn0001301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZF0-1", "uniprot_id": "KLHL2_RAT", "id": "F1LZF0-1", "name": "Kelch-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------MESPPLPPACTKQGHQKPLDSKDENPEKHCPLTVNPWHMKKAFKVMNELR--SQNLLCDVTIVAEDMEIPAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY-AEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRMLMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZP3-1", "uniprot_id": "KLHL2_MOUSE", "id": "Q8JZP3-1", "name": "Kelch-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------METPPLPPACTKQGHQKPLDSKDENPEKHCPLTVNPWHMKKAFKVMNELR--SQNLLCDVTIVAEDMEIPAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLVDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY-AEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRMLMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95198-1", "uniprot_id": "KLHL2_HUMAN", "id": "O95198-1", "name": "Kelch-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------METPPLPPACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELR--SQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTY-AEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRILMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATTNEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKI1-1", "uniprot_id": "A0A8M9PKI1_DANRE", "id": "A0A8M9PKI1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MEIHPL---CTKLCHHKAVELKDDVYEKQSAVTINPRHMKKAFRIMNELR--SQSVLCDVTIIAEDVEIAAHRVVLAAGSPYFHAMFTGEMTESRQKKVRIKEIDGWTLGMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQEVKKACCEFLITQLHPTNCLGIRAFADLHACTELLNLANTY-AEQHFSEVVQSEEFLNLGMDQVCSLIASDKLTIPSEEKVFEAVIAWVMHDKDVRQEHLAHLMEHVRLPLLSREYLVQRVEEETLVKNSSACKDYLIEAMKYHLLPADQRSMMKTIRTRVRTPISYPKVMMVVGGQAPKAIRSVECYDFEEERWFQVAELPSRRCRAGVVFMGGVVYAVGGFNGSLRVRTVDAYDPVKDEWCCVSSMQDRRSTLGCAFLSGLLYAVGGFDGSTGLATVEAYNAKANEWFHVNPMNTRRSSVGVGVVGGLLYAVGGYDGATRQCLSTVEAYNPNTNEWSYTAEMGTRRSGAGVGVLKGLLYAVGGHDGPLVRKSCEVFDPATNTWKQVADMNMCRRNAGVCALSNLLYVIGGDDGSCNLASVEFYNPNTDKWTLLPTCMSTGRSYAGVTVIDKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LZ52-1", "uniprot_id": "KLHL3_RAT", "id": "F1LZ52-1", "name": "Kelch-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------MEGESVKPSPQPTEQAGDGE-KNRRMITVNPAHMGKAFKVMNELR--SKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAY-AEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGQWVSASGA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E0CZ16-1", "uniprot_id": "KLHL3_MOUSE", "id": "E0CZ16-1", "name": "Kelch-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------MEGESVKPSPQPTAQAEDEE-KNRRTVTVNAAHMGKAFKVMNELR--SKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAY-AEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UH77-1", "uniprot_id": "KLHL3_HUMAN", "id": "Q9UH77-1", "name": "Kelch-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------MEGESVKLSSQTLIQAGDDE-KNQRTITVNPAHMGKAFKVMNELR--SKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAY-AEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6F9-1", "uniprot_id": "KLHL3_DANRE", "id": "E7F6F9-1", "name": "Kelch-like protein 3", "aln": "-----------------------------------------------------------------------------------------------MVLWGFFLRFRFFLTCGRNCIQKTLDSQDDA-KDPGLHTFSHTHMRKAFLLMNDLRSHSRKMLCDVLLVAGEVEIPAHRVVLASCSPYFCAMFTGDMSESKANHVEIRDVDGQTLLKLVDYIYSAEIEVSEENVQVLLPAASLLQLMDVRQVCCDFLQTQLHPTNCLGIRAFADLHACTVLLSQAHAYAAEQHFTDVMVGEEFMALSLQQVCSLISSDKLTVSTEEKVFEAMVAWIKHDKEARLEHMPKLMEHVRLPLLSRDYLVQIVEEEPLIKNNNTCKDFLIEAMKYHLLPADQRHLIKTDRTRPRTPISLPKVMMVVGGQAPKAIRSVECYDFQEDRWYQVADLPSRRCRAGVVYMAGKVYAVGGFNGSLRVRTVDVYDGLKDQWSSIPSMQERRSTLGAAVLGDLLYAVGGFDGSTGLSSVEAYNPKANEWMFVAPMNTRRSSVGVGVVDGKLYAVGGYDGASRQCLSTVEEFNPVSNKWCYVSDMSTRRSGAGVGVLSGQLYAAGGHDGPLVRKSVEVYDPTTNTWRQVCDMNMCRRNAGVCAINGLLYVIGGDDGSCNLSSVEYYDPAADKWSLIPTNMSNGRSYAGVSVIDKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04652-1", "uniprot_id": "KELC_DROME", "id": "Q04652-1", "name": "Ring canal kelch protein", "aln": "MIALSALLTKYTIGIMSNLSNGNSNNNNQQQQQQQQGQNPQQPAQNEGGAGAEFVAPPPGLGAAVGVAAMQQRNRLLQQQQQQHHHHQNPAAEGSGLERGSCLLRYASQNSLDESSQKHVQRPNGKERGTVGQYSNEQHTARSFDAMNEMR--KQKQLCDVILVADDVEIHAHRMVLASCSPYFYAMFT-SFEESRQARITLQSVDARALELLIDYVYTATVEVNEDNVQVLLTAANLLQLTDVRDACCDFLQTQLDASNCLGIREFADIHACVELLNYAETY-IEQHFNEVIQFDEFLNLSHEQVISLIGNDRISVPNEERVYECVIAWLRYDVPMREQFTSLLMEHVRLPFLSKEYITQRVDKEILLEGNIVCKNLIIEALTYHLLPTET----KSARTVPRKPVGMPKILLVIGGQAPKAIRSVEWYDLREEKWYQAAEMPNRRCRSGLSVLGDKVYAVGGFNGSLRVRTVDVYDPATDQWANCSNMEARRSTLGVAVLNGCIYAVGGFDGTTGLSSAEMYDPKTDIWRFIASMSTRRSSVGVGVVHGLLYAVGGYDGFTRQCLSSVERYNPDTDTWVNVAEMSSRRSGAGVGVLNNILYAVGGHDGPMVRRSVEAYDCETNSWRSVADMSYCRRNAGVVAHDGLLYVVGGDDGTSNLASVEVYCPDSDSWRILPALMTIGRSYAGVCMIDKPMXMEEQGALARQAASLAIALLDDENSQAEGTMEGAIGGAIYGNLAPAGGAAAAAAPAAPAQAPQPNHPHYENIYAPIGQPSNNNNNSGSNSNQAAAIANANAPANAEEIQQQQQPAPTEPNANNNPQPPTAAAPAPSQQQQQQQAQPQQPQRILPMNNYRNDLYDRSAAGGVCSAYDVPRAVRSGLGYRRNFRIDMQNGNRCGSGLRCTPLYTNSRSNCQRQRSFDDTESTDGYNLPYAGAGTMRYENIYEQIRDEPLYRTSAANRVPLYTRLDVLGHGIGRIERHLSSSCGNIDHYNLGGHYAVLGHSHFGTVGHIRLNANGSGVAAPGVAGTGTCNVPNCQGYMTAAGSTVPVEYANVKVPVKNSASSFFSCLHGENSQSMTNIYKTSGTAAAMAAHNSPLTPNVSMERASRSASAGAAGSAAAAVEEHSAADSIPSSSNINANRTTGAIPKVKTANKPAKESGGSSTAASPILDKTTSTGSGKSVTLAKKTSTAAARSSSSGDTNGNGTLNRISKSSLQWLLVNKWLPLWIGQGPDCKVIDFNFMFSRDCVSCDTASVASQMSNPYGTPRLSGLPQDMVRFQSSCAGACAAAGAASTIRRDANASARPLHSTLSRLRNGEKRNPNRVAGNYQYEDPSYENVHVQWQNGFEFGRSRDYDPNSTYHQQRPLLQRARSESPTFSNQQRRLQRQGAQAQQQSQQPKPPGSPDPYKNYKLNADNNTFKPKPIAADELEGAVGGAVAEIALPEVDIEVVDPVSLSDNETETTSSQNNLPSTTNSNNLNEHND", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . . * ::* **::* .: **** ::* ::*: ***:***: **** **** .: **: :: ::.:*. :* *:**:*:* ::*.*:******.**.**** :*:. **:** :**.. ****** ***:*:*. **. *.:* **** :*: :**: *. :** ***..*::::..**:*:*.:::*: :: * :. . ********:*.::*:.* *::* *::.. .**: :***:.***** : *. ** *.*:. **:::*:************ **:.* :* * *::*.****:*: :.. *:*************** ** .*:* ..*. ****** *.*.. :********:***::.* *. *:: * .: .*.*********** * ********* :*****:** :*. :: * ::*.:**********.. ***.******:**:* *.:* **:*:.*.**. ******* * ..****:*****:.**:*** * * :*.* ::.: *: ****** : . ", "identical_positions": 285, "similar_positions": 173, "identity": "19.19%" }, { "cls_id": "homologset.agr.FB:FBgn0001308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6QLM7-1", "uniprot_id": "KIF5A_RAT", "id": "Q6QLM7-1", "name": "Kinesin heavy chain isoform 5A", "aln": "---MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQG--DDSVIIG-GKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVRGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENIETEQKLSGKLYLADLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEDSALAAEICEETPVNDNSSIVVRI-------------APEER-QKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKEEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESEPQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNG----EIKLPVEIS---GAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQTVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPD----TQDAEEVKKALELQMENHREAHHRQLARLRDEINEKQKTIDELKDLDQKLQLELEKLQADYERLKNEENEKSAKLQELTFLYERHEQSKQDLKGLEETVA---------------------------RELQTLHNLRKLFVQDVTTRVKK-SAEMEPEDSGGIHSQKQKISFLENNLEQLTEVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPG-HYPASSPTNPYGTRSPE-CISYTNNLFQNYQNLHLQAAPSSTSDVYFA----SNGATS-VAPLASYQKANTDNGNATDINDNRSDLPCGYEAEDPAKLFPLHQETAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33175-1", "uniprot_id": "KIF5A_MOUSE", "id": "P33175-1", "name": "Kinesin heavy chain isoform 5A", "aln": "---MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQG--DDSVIIG-GKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENVETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEDSALGAELCEETPVNDNSSIVVRI-------------APEER-QKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMRDLSEFSVIVGNG----EIKLPVEIS---GAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQTVELKKRHLEESYDSLSDELARLQAHETVHEVALKDKEPD----TQDAEEVKKALELQMENHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYERLKNEENEKSAKLQELTFLYERHEQSKQDLKGLEETVA---------------------------RELQTLHNLRKLFVQDVTTRVKK-SAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPG-HYPASSPTNPYGTRSPE-CISYTNNLFQNYQNLHLQAAPSSTSDMYFA----SSGATS-VAPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQAKLFPLHQETAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12840-1", "uniprot_id": "KIF5A_HUMAN", "id": "Q12840-1", "name": "Kinesin heavy chain isoform 5A", "aln": "---MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQG--DDSVVIG-GKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRI-------------APEER-QKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNG----EIKLPVEIS---GAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPD----TQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVA---------------------------RELQTLHNLRKLFVQDVTTRVKK-SAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPG-HYPASSPTNPYGTRSPE-CISYTNSLFQNYQNLYLQATPSSTSDMYFANSCTSSGATSSGGPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQAKLFPLHQETAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATT8-1", "uniprot_id": "A0A8M3ATT8_DANRE", "id": "A0A8M3ATT8-1", "name": "", "aln": "---MADISAECNIRVLCRFRPLNQSEILRGDKFMPTFQG--DDTVIIA-GRSYVFDKVFPTNCTQEQVYNTCAQQIVKDVLDGYNGTIFAYGQTSSGKTYTMEGKLHDANGRGIIPRIAEDIFNHIYTMDENLEFHIKVSYFEIYMDKIRDLLDVTKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMDLIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQEHVETEQKLCGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTMFICCSPSAYNDAETKSTLMFGQRAKTIMNSASVNLELTAEQWKRKYEKEKEKNKDLKESMQRLEAELNHWRNGESVVLITPVS----PAECDVTEDTAVDNQSHGQTEL-------------IPEQHNSRYEEEIQQLYRQLDDKDDEINLQCQLVEKLKEQMLDQEELLACARADLERVQCDVRRLQADSESSKLEVQEVLQALEELALSYDHKSLEAQDNSRHNRRLTEELAHTTSALLSLESDFSRLQEVNGQQRKRITEVLNTLVKDLNDFSFILGNG----DLRLPSELS---GVLEEEYAVVCVYMSKVKSELKTLVKRCRQLESLQTDCHRKMEETGRELSSCQLLISQHEAKIRSLTEYMQNMELKKRQLEENYDCLSEELAKLQNTESILDRPLDTDES-------VNVKSHKAVDQKSEVQREPQHKQLGRLRDDINHKQKIIDELTDDNQRLDLQLEQLSVEFSVLKSREHEKSRQLEELRYLHERQEQTRQDMKGLEETVVSAYRKYDISNDNNNGVYDRPAHFSLKARELQTLHNLRKLFVQDLTARVKR-SSELDPDDSSGCSTQKQKISFLENNLDQLTKVHKQLVRDNADLRCELPKLEKRLRSTAERVRALEEALREAKEGAMKDRRRYQQEVERIKDVMRSRNPFRRPQAALIAKPIRPG-HYPASLSANHMFLRSRDQPITFSNAMFNSSS--EKQKLTSSKTESSLTSRTLSEHERQTHETTNCTQKLHITNGNSSDVNDN-SECRSSTITDEPQQKHHQEQPVAS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O60282-1", "uniprot_id": "KIF5C_HUMAN", "id": "O60282-1", "name": "Kinesin heavy chain isoform 5C", "aln": "---MADP-AECSIKVMCRFRPLNEAEILRGDKFIPKFKG--DETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKD-QKNLEPCDNTPIIDNIAPVVAG-------------ISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTN----DVKTLADVN---GVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVS---------------------------RELQTLHNLRKLFVQDLTTRVKK-SVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPG-HYPASSPTAVHAIRGGG---------------------GSS-------------------SNSTHYQK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28738-1", "uniprot_id": "KIF5C_MOUSE", "id": "P28738-1", "name": "Kinesin heavy chain isoform 5C", "aln": "---MADP-AECSIKVMCRFRPLNEAEILRGDKFIPKFKG--EETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVLQHLEMELNRWRNGEAVPEDEQISAKD-QKSLEPCDNTPIIDNITPVVDG-------------ISAE-KEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTN----DVKTLADVN---GVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVS---------------------------RELQTLHNLRKLFVQDLTTRVKK-SVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPG-HYPASSPTAVHAVRGGG---------------------GGS-------------------SNSTHYQK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NGN8-1", "uniprot_id": "A0A8M1NGN8_DANRE", "id": "A0A8M1NGN8-1", "name": "Kinesin-like protein", "aln": "---MVDA-AECCVKVMCRFRPLNESEINRGDKYIPKFKG--EDTVVIA-GKPYIFDRVLPPNTTQEQVYDTCAKQIVKDVLDGYNGTIFAYGQTSSGKTHTMEGQLHNAQLMGIIPRIAQDIFEHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPFVKGCTERFVSSPEDVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGSVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVYNEAETKSTLMFGQRAKTIKNTVSVNMELTAEEWKKKYEKEKEKTRNLKIIIQRLENELKRWRKGETVPVNEQHSNKE-SKN---CEAAPVIDTSAPPPEP-------------LSDAEKTQYEELINDLYQQLDDKDDEINQHSQLAEDLKQQMVDQDELLASTRRDYEKIQEDLNRLQRENETAKEEVKEVLQALEELAVNYDQKSHEVEEKSKTNNQLSDELVQKSSALAGVERDLSSLKELSEHHRRRSAEILSLLLRDLCEIGSVIALN----DHK-LSELN---GGMEEEFTMARLFISKMKSEVKSLVNRSKQLESTQSDTMRKMQANEKELASCQMLISQHQAKIKSLTDYMQNMEQKKRQLEESHDSLTEELAKLHAEERMHEVSVLDKEKEHMSRMQDAEEMKKALEQQMESHRETHQKQLSRLRDEIEEKQRILDELKDVNQALELEQKKLMSDYEKLQQEDQKKDERLQKLLFLNEKKEQAKEDLKGLEETVA---------------------------KELQTLHDLRKLFIQDINNRIGR-SVELDTDESGGSLAQKQKIIFLENNLEQLTKVHKQLVHDNADLRCELPKLEKRLRATAERVKILESALREAKESAMRDRKKYQQEVDRIKEVIRAKNQSRRNHTAQIAKPIRAGHHHPVASASPGHSVRGGT---------------------PSPRRHHQHQP---HHHQQPPQPHHPHYQHQPH---------------------HQPQQLQYHHRSK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PQA9-1", "uniprot_id": "KINH_RAT", "id": "Q2PQA9-1", "name": "Kinesin-1 heavy chain", "aln": "---MADP-AECNIKVMCRFRPLNESEVNRGDKYVAKFQG--EDTVMIA-SKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKTLRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTADKDVAITNDKPAAAIGMA-------G-SFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN----DVKQPEGT----GMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDSLGEELVQLRAQEKVHEM-----EKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKEKLITDLQDQNQKMVLEQERLRVEHERLKAVDQEKSRKLHELTVMQDRREQARQDLKGLEETVA---------------------------KELQTLHNLRKLFVQDLATRVKK-SAEVDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPG-QHPAASPTHPGAVRGGG-------------------------------------------SFVQNNQPVGLRGGGGKQA-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61768-1", "uniprot_id": "KINH_MOUSE", "id": "Q61768-1", "name": "Kinesin-1 heavy chain", "aln": "---MADP-AECNIKVMCRFRPLNESEVNRGDKYVAKFQG--EDTVMIA-SKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKTLRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTADKDIAITSDKPAAAVGMA-------G-SFTDAERRKCEEELAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN----DVKQPEGT----GMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDSLGEELVQLRAQEKVHEM-----EKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKEKLITDLQDQNQKMVLEQERLRVEHERLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVA---------------------------KELQTLHNLRKLFVQDLATRVKK-SAEVDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPG-QHPAASPTHPGTVRGGG-------------------------------------------SFVQNNQPVGLRGGGGKQS-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33176-1", "uniprot_id": "KINH_HUMAN", "id": "P33176-1", "name": "Kinesin-1 heavy chain", "aln": "---MADL-AECNIKVMCRFRPLNESEVNRGDKYIAKFQG--EDTVVIA-SKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVI-------G-NFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN----DVKQPEGT----GMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEM-----EKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVA---------------------------KELQTLHNLRKLFVQDLATRVKK-SAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPG-QHPAASPTHPSAIRGGG-------------------------------------------AFVQNSQPVAVRGGGGKQV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRM1-1", "uniprot_id": "A0A0R4IRM1_DANRE", "id": "A0A0R4IRM1-1", "name": "Kinesin-like protein", "aln": "---MADP-AECTIKVMCRFRPLNSAEVMRGDKYIPSFQG--EDSVVIG-GKPYVFDRVFQSNTTQEQVYNACAQKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGNLHDSDCMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPEEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEAT-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSFNEAETKSTLMFGQRAKTIKNTVSVNVELTAEQWKKKYEKEKEKNKTLKNTITWLENELNRWRNGESVPVDEQYDKEKANADVLALDN--VVNNDKFTSTPSVP-------GLKFTDAEREKCEAELAKLFKQLDDKDDEINQQSQLAEKLKQQMLDQEELLASTRRDHDNLQAELTRLQMENEASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEFETLNEELNQKSSVLASIESELQKLKEMTNHQKKRVTEMMSSLLKDLAEIGIAVGSN----DIKH-EGG----GLIDEEFTVARLYISKMKSEVKTLVKRSKQLESAQTESNKKMDENEKELAACQLRISQYEAKIKSLSEYLQNIEQKKRQLEENVDSLNEELVKLSAQEKVHAM-----EKE--NEIQSANEVKAAVEQQIQNHREAHQKQLSSLRDELETKEKLITELQDQNQKIILEQERLKVEHEKLKSTDQEKSRKLHELTVMQDRREQARQDLKGLEETVA---------------------------KELQTLHNLRKLFVQDLATRVKK-SAEMDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAARDRKRYQQEVDRIKEAVRAKNMARRGHSAQIAKPIRPG-QPPVASPTHPNVIRSGA-------------------------------------------GLFQNNQSAGIRGGGGVKQ-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17210-1", "uniprot_id": "KINH_DROME", "id": "P17210-1", "name": "Kinesin heavy chain", "aln": "MSAEREIPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLKGKVEKLEIELARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVMEQEELIANARREYETLQSEMARIQQENESAKEEVKEVLQALEELAVNYDQKSQEIDNKNKDIDALNEELQQKQSVFNAASTELQQLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPGESSIDLKMSALAGTDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQADSNKKISEYEKDLGEYRLLISQHEARMKSLQESMREAENKKRTLEEQIDSLREECAKLKAAEHVSAVN---AEEK-----QRAEELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKDVHQKLLLAHQQMTADYEKVRQEDAEKSSELQNIILTNERREQARKDLKGLEDTVA---------------------------KELQTLHNLRKLFVQDLQQRIRKNVVNEESEEDGGSLAQKQKISFLENNLDQLTKVHKQLVRDNADLRCELPKLEKRLRCTMERVKALETALKEAKEGAMRDRKRYQYEVDRIKEAVRQKHLGRRGPQAQIAKPIRSG---QGAIAIRGGGAVGGP-------------------------------------------SPLAQVNPVNS-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::*:*******.:* *.*:: * . ::. : .: * **:*: .. :**:**. .* .**.*** *****************:**** : :. ******..***::**:*: **********:***:*********:*.**:*********:*:*.*****.**::::: *:***:***:**************:****:***: :.::**.*****.***************:***********************:.. :::******:*****:*****.***:.*****: :*::****** **:****: * ..** *****:**::*******. : : ** ** :** ** * . : *::******:*** :.* *.** *:::*:**:. :* : : :* :: ::* :.:::* **:**********:.**:** * :::.: * :** :. :.: . : . *:::. ::::* :*:: *::** :.. :. . : : . ::*::::. :::**:*:* *.:.:*. ::*. * : :*:. ::*. :: ***::*:::** : :: * *:* ***. *.* :* .:* * : * : : .: : : **.: :*:. ***:: * : : :: * .* : * ::: :.. :: : ::. .*.:: :::**:::*:****:** :******:*****:**: *: : : : :: .* :***** ******:***:******:*****************.* ***: ** **:****.* :*:::** **:***:.:* : :* * ****:*.* : . . : ", "identical_positions": 418, "similar_positions": 278, "identity": "38.24%" }, { "cls_id": "homologset.agr.FB:FBgn0001311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M6YW55-1", "uniprot_id": "A0A8M6YW55_DANRE", "id": "A0A8M6YW55-1", "name": "chitin synthase", "aln": "-----------------------------MEPSPDLKLWDVEKEENKQNEKEQQQKFWDTCREVPIIQDD------QIPRNRTHCLKWFACTVVGMIVFILALLSKTSFLLLITFGNNQ----------------TVIIHSDQKPTALLAIGFVLVGPSFLLLLKGTWKFIFKNSTMPSKKTCLWVLCVEILVALGAAVLTIVAMPHFDIVTNVMILN--SVSILSAIFQVIADCRAK-ERKRFILLPLLSIVFIVLGYVLFVVNYLAFESSLLIPILLAIFGTICVSVNWWENYS----ALFTILSLNEIPKDIAKSSNAVNIISSLTRILITS-----------AVIGVYVALIGDGWKSVKIVFETVVIAL--VVIQTLSSALCRWFVVVACK-----MHALRRSFVMPMYLASIVVLAVFLSPLVITFPVSNNTISYLVGNPVPLSSTEWVELLLIDTIETLLTRDIVVNMKIVGLV--CLGCSALCWWLGLVLSTVYIWFLKIHRIERTKDLFVQRMYEGAFLEQSLMLNTRFEIRKKIKEK--KHEKET------------------------------IRVFLCATMWHETYDEMMKIIISMFRMDKYRPKTEQKSD---------VEFEFHIYVDDAFKDVKEER--HTNEYVEILVDVIKEVYLNFSEEDSSVFKNQQPLPSQKIISTPFGGRLEYTLPKGN-VMIVNLKDKKLIRHKKRWSQIMYLYYILGWRLHKKYYEKFEAGEDLDCLKVAGEQTESLKEKLKRERENTYILALDGDTDFQPSAVMLLIDRLKLYPDVGAACGRIHPTG-------TGPMVWYQKFEYAVG--HWLQKTAEHVLGCVLCSPGCFSLFRGAALMDDN-----VMKRYTTRASEASHYVQYDQ----GEDRWLCTLLLQQG---WRVEYNAASDAYTNAPQDFKEFYNQRRRWGPSTMANTIDLLGSGQLTAERNSSIS--------KLYILYQVLSMGASILGPATVCLMISGGFVFVFKMSENDALILAIVPPAIYLILCFKLKSDTQLTIAAIMSIMYAFLMTGSILSIIGDLVLQDTFLTP----------SGLFLIGMVVLYLITAGLHPKEFSLIIYGLLYFICIPSGYLLLAIYSIVNMNNVSWGTRESGGQAKTSAVNSLKKKFLNAT-----------------------------------CCKCPCLEYEDETRREVTQVE----DKPEGENIS---EILSENTQIIPQNR----KPWIHSLQPKFGFSLRSESAC---------------------------------ELSEEELIFWKEMQKKYLHPLEEKPEQLAIIANDLRELRNKVTFVYFFCNALWLVATFFLQAIGGAVTIKIPKIYPN---------GTRSPTETLSLDPIALMFLLGFAALLIIQFIAMLYHRIYTFIHFVAYADTEIKAHR-----------KQSQQVVKFMDHHETFEGD------------------------------------------------------TPISTKRKSFISDGFFT-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P1A8-1", "uniprot_id": "A0A8M9P1A8_DANRE", "id": "A0A8M9P1A8-1", "name": "chitin synthase", "aln": "-----------------------------MKQTPEFR------------------KFWDVGKEVPFIQDE------QMPKKLTHCLKWFSCTLVGMLVFVLALLSKTSFLLLITFGNNQ----------------TEIVPLDQKPTALLAIGFVLVGPSVLLLLKSTWKFIFKNGNMPSKKTVFWVLCVEILVALGAAVLTIVAMPHFDIVTNVMILN--SISILSAFFQVDAEFLGR-KRKHLLIPPFFSIFFIVLGYVLFAVNYLVFESSLRVSVGLAMFGTICVSVNWWENYS----PLFTILSLKKISKDMVKSSNAVNIISSLTRILITS-----------AVIGAYVALTGDGWKSVKIIFETVVIAL--VVIQTLSSALCRWFVVVACK-----MHALRRSFVMPMYFASIIVLAVFLSPLIYSLPLSNNTSITLEK---SESSTEWVEVLLTDAIQTLLTRDIVVNMKTEGLV--CLGCSALCWWLGLVLSTIYIWFLKIHRIERTQDLFVQRMYEGAFLEQSLMLNTRFEIGKKIKENEVAEPTKK------------------------------IKVFLCATMWHETYDEMMKIIISMFRLDKYRPKHGKHSD---------VEFEFHIYFDDAFKDVNNGRGRLTNEYAEILVDVIKEIYIIFSEEDPCVFKEMPSLPSQKIIHTPYGGRLEYTLPNGN-VMMVHLKDKQLIRHKKRWSQIMYLYYILGWRLNKQYYENLKAGE----------EPELIKKKLKSDRENTYILALDGDTDFQPSAVMLLIDRLKIYPEVGAACGRIHPTG-------TGPVVWYQKFEYAVG--HWLQKTAEHVFGCVLCSPGCFSLFRGAALMDDN-----VMKRYTTKASEASHYIQYDQ----GEDRWLCTLLLQQG---WRVEYNAASDAYTNAPQDFKEFYNQRRRWGPSTMANTIDLLGSGQLTAQRNSSIS--------KLYILYQVISMAASILGPATICLMISGSFVFIFNMEENSALALAIVPPTVYLILCFKLKSDVQITIAAIMSLLYAFLMAGTVLSIIGDLVKQNTFMTP----------SGLFLIGMVILYLTTAALHPKEFSMVIYGLLYFICVPSGYLLLAIYSIVNMNNVSWGTRESGVQVKTSALDNIKKKFMKAT-----------------------------------CCRCPCFESEDEMNKEVLQAE----NTNKTEMLQMTLKIQSANDFAINTHKSVDKQTWIEHLLPKFGFCLTPES-----------------------------------ELSMDEIDFWIDLQKKYLEPLKENKEQQEKIANDLRELRNKATLVYFFCNALWLVATFFLQAIGEAVYIKIPKIYPN---------GTYAAKELLSLDPIELMFLLGFAGLLLMQFFAMLYHRIYTLIHFVAYAETEEKAPR-----------KKVAQIVD--DNHETSEDD------------------------------------------------------TICFENPYVMTRHITYV-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPN4-1", "uniprot_id": "Q8IPN4_DROME", "id": "Q8IPN4-1", "name": "chitin synthase", "aln": "MSAMRHRPMAPPGQGPGAGTAGEHVDSDDNNFTDDESSPLTHDIYGGSQRTIQETKGWDVFRDPPIKIETGSTANQECLELTVKILKIFAYVITFIIVLTGGVIAKGTMLFMTSQVRKDKKMEYCNKDLGRDKSFVVRLPEEERVAWIWALLIAYALPEIGALIRSARICFFKTFKVPKTGHFLFVWLMESLSAVGMALLMFVVLPQIDAIQGAMLTN--CLCVVPGIFGLLSRTSKEGKRFVKVIIDLAAVAAQVTGLVIWPLLENRRE------LWVIPVACVMISCGWWENYVSPQSPLGLVRALGRIKEEMKYTRYFCHIFLSIWKILLFFTVTLLIYWAQGEEPGNLFAMYGDAFGPHKIIVYELPAGLGGVLPDTLESANIDTVDVDAAYNTVVYVLLLQIFGAYLCYIFGKFACKILIQGFSYAFPVSLTVPLSVTFLIAACGIRIDDPCFFHDTIPDYLFFTSPSNFRFNNFVTEQMAWAWILWLLSQTWIALHIWTPKCERLATTEKLFVQPMYSSLLIDQSMALNRRRDDQADVKTEDLSEIEKEKGDEYYETISVHTDRSSAPNKPSIKSSDNITRIYSCATMWHETKDEMIEFLKSIMRMDEDQCARRVAQKYLRVLDPDYYEFETHIFFDDAFEISDHSD------DDIQCNRFVKLLIATMDEAASEIHQTTIRLRPPKKYPTPYGGRLVWTLPGKT-KFITHLKDKDRIRHRKRWSQVMYMYYLLGHRLMELPIS---------------------VDRKDAIAENTYLLTLDGDIDFKPNAVTLLVDLMKKNKNLGAACGRIHPVG-------SGPMVWYQLFEYAIG--HWLQKATEHMIGCVLCSPGCFSLFRGKALMDDN-----VMKKYTTRSDEARHYVQYDQ----GEDRWLCTLLLQRG---YRVEYSAASDAYTHCPEGFNEFYNQRRRWVPSTIANIMDLLADAKRTIKINDNIS--------LLYIFYQMMLMGGTILGPGTIFLMLVGAFVAAFRIDNWTSFHYNIVPILAFMFICFTCKSNIQLFVAQVLSTAYALIMMAVIVGTALQLG-EDGIGSP----------SAIFLISMVGSFFIAACLHPQEFWCITCGLIYLLSIPSMYLLLILYSIINLNVVSWGTREVVAKKTKKELEAEKKAAEEAKKRVKQKSMLSFLQSGIGDNGDEEGSVEFSLAGLFRCIFCTHGKTSDEKQQLTSIAESLDTIKHRMDTIESAVDPHGHHASRHGRRRTTSSGSKDHHLLTSVAEKSGDESDESDSDTSAEPKQERDFLTNPYWIEDPDVRKGEVDFLSSTEIQFWKDLIDQYLYPIDNDPVEQARIAKDLKELRDSSVFAFFMINALFVLIVFLLQLNKDNIHVKWPFGVRTNITYDESTQEVHISKEYLQLEPIGLVFVFFFALILIIQFTAMLFHRFGTISHILASTELNFCKKKSEDLTQDQLIDKHAVEIVKNLQRLQGIDGDYDNDSGSGPDRIARRKTIQNLEKARQPRRQIGTLDVAFKKRFLKLTADAENNPATPILTRRLTMRAETIRALEVRKNSVMAERRKSAMQTLGAKNEYGITTGAPINNNGALPNQRSGRVSNAGISIKDVFNVNGGGAEQIYGSNGGGTINQGYEHVIDEDGDGNSLRLTTRNPHPHPHHQVSWGQNTNGGGGNGTGRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14180-1", "uniprot_id": "CHS2_YEAST", "id": "P14180-1", "name": "Chitin synthase 2", "aln": "-------------------------------------------------------------------------------------------------------MTRNPFMVEPSNGSPN-----------------------RRGASNLSKFYANAN-------SNSRWANPSEESLEDSYDQSNVFQGLPASPSRAALRYSPDRRHRTQFYRDSAHN--SPVAPNRYAANLQESPKR---------AGEAVIHLSEGSNLYPRDN---------------------------------------ADLPVDPYHLSPQQQPSNNLFGSGRLYSQS-------------------------SKYTMSTTSTTAPS----LAEADDEKEKYLTSTTSYD--------DQSTIFSADTFNETKFELNHPTRQQYVRRANSESKRRMVSDLPPPSKKKALLKLDNPIPKGLLDTLP---------------------------------------RRNSPEFTEMRYTACTVEPDDFLREGYTLRFAEMNR-------------------------------------ECQIAICITMYNEDKYSLARTIHSIMKNVAHLCKREKSHVWG----PNGWKKVSVILISDGRAKVNQGS-----LDYLAALGVYQEDMAKASVNGDPVKAHIFELTTQVSINADLDYVSKDIVPVQL-VFCLKEENKKKINSHRWLFNAFCP-----------------------------------------VLQPTVVTLVDVGTRLNNTAIYRLWKVFDMDSNVAGAAGQIKTMKGKWGLKLFNPLVASQNFEYKIS--NILDKPLESVFGYISVLPGALSAYRYRALKNHEDGTGPLRSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDAKWVLKYVKEATGETDVPEDVSEFISQRRRWLNGAMFAAIYAQLHFYQIWKTKHSVVRKFFLHVEFLYQFIQMLFSWFSIANFVLTFYYLAGSMNLVIKHGEALFIFFKYLIFCDLASLFIISMGNRPQGAKHLFITSMVILSICATYSLICGFVFAFKSLASGTESHKIFVDIVISLLSTYGLYFFSSLMYLDPWHMFTSSIQYFLTLPAFTCTLQIFAFCNTHDVSWGTKGSTQESKQLSKAIVVQGPDGKQ--------------------------------------IVETDWPQEVDKKFLEIK--------------------------------------------------------------------------------------------------SRLKEPEFE--ESSGNEKQSKNDYYRDIRTRIVMIWMLSNLILIMSIIQVFTPQD------------------------TDNGYLIFILWSVAALAAFRVVGSMAFLFMKYLRIIVSYRNKVEGSGSWEVSK--------------LDLPNVFHKKG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P29465-1", "uniprot_id": "CHS3_YEAST", "id": "P29465-1", "name": "Chitin synthase 3", "aln": "--------------------------------------------------------MTGLNGDDPDDYYLNLNQDEESLLRSRHSVGSGAPHRQGSLVRPERSRLNNPDNPHFYYAQKT---------------------QEQMNHLDVLPSSTGVNPNATRRSGSLRSKGSVRSKFSGRETDSYLLQDMNTTDKKASVKISDEGVAEDEFDKDGDVDNFEESSTQPINKSIKPLRKETNDTLSFWQMYCYFITFWAPAPILAFCGMPKKER----------------------------QMAWREKVALISVILYIGAIVAFLTFGFTKTVCSS--------------------SKLRLKNNEVSTEFVVINGKAYELDTSSRSGIQDVEVDSDTLYG-PWSDAGKDASFLFQNVNGNCHNLITPKSNSSIPHDDDNNLAWYFPCKLKNQDGSSKPNFTVENYAGWNCHTSKEDRDAFYG----------------LKSKADVYFTWDGIKNSSRNLIVYNGDVLDLDLLDWLEKDDVDYPVVFDDLKTSNLQG--------------------------------YDLSLVLSNGHERKIARCLSEIIKVGEVDSKTVGCIAS-----------DVVLYVSLVFILSVVIIKFIIACYFRWTVARKQGAYIVDNKTMDKHTNDIEDWSNNIQTKAPLKEVDPHLRPKKYSKKSLGHKRASTFDLLKKHSSKMFQFN-----------------------------------ESVIDLDTSMSSSLQSSGSYRGMTTMTTQNAWKLSNENKAVHSRNPSTLLP-----TSSMFWNKATSSPVPGSSLIQSLDSTIIHPDIVQQPPLDFMPYGFPLIHT----ICFVTCYSEDEEGLRTTLDSLSTTDYPNSHKLLMVVCDG-------LIKGSGNDKTTPEIALGMMDDFVTPPDEVKPYSYVAVASGSKRHNMAKIYAG--------FYKYDDSTIPPENQQRVPIITIVKCGTPAEQGAAKPGNRGKRDSQIILMSFLEKITFDERMTQLEFQLLKNIWQITGLMADFYETVLMVDADTKVFP----DALTHMVAEMVKDPLIMGLCGETKIANKAQSWVTAIQVFEYYISHHQAKAFESVFGSVTCLPGCFSMYRIKSPKGSDGYWVPVLANP--------------------------------------DIVERYSDNVTNTLHKKN---------------LLLLGEDRFLSSLMLKTFPKRKQVFVPKAACKTIAPDK---------------------------------------------FKVLLSQRRRWINSTVHNLFELVLIRDLCGTFCFSMQFVIGIELIGTMVLPLAICFTIYVIIFAIVS--------------KPTPVITLVLLAIILGLPGLIVVITATRWSYLWWMCVYICALPIWNFVLPSYAYWKFDDFSWGDTRTIAGGNKKAQDENEG-------------------------------------------------EFDHSKIKMRTWREFEREDILNRKEESDSFVA---------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . .. : :: . : . . : : : . : : . . : . : . : .. : :: *. . .: : .: . : .::: : .. : . : * : . : : . : : : :: . . : . . : .. .: . ..:. : . : ::. . :: :. . . .*. : :: : . *: : .: . : :* : . * : :: : : . : . : . .: : : : :. . * . :: . : : .. . ::: : : : :: : : . : : : : : : . . : .. ", "identical_positions": 7, "similar_positions": 155, "identity": "0.41%" }, { "cls_id": "homologset.agr.FB:FBgn0001319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UH73-1", "uniprot_id": "COE1_HUMAN", "id": "Q9UH73-1", "name": "Transcription factor COE1", "aln": "---------------------------------------------------------------------MFG----------------------------IQESIQRSGSSMKEEPLG-SGMNAVRTWMQGAGVLDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGT--------------------PSYLEHAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQ-GFTRN-SSSVSPHG-YVPSTTPQQTNYNS-VTTSMNGYGSAAMSNLG--GSPTFLNGSAANSPYAIVPSSPTMASS-TSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPP-PTCTSTNGNSLQ---------------AISGMIVPPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07802-1", "uniprot_id": "COE1_MOUSE", "id": "Q07802-1", "name": "Transcription factor COE1", "aln": "---------------------------------------------------------------------MFG----------------------------IQESIQRSGSSMKEEPLG-SGMNAVRTWMQGAGVLDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGT--------------------PSYLEHAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQ-GFTRN-SSSVSPHG-YVPSTTPQQTNYNS-VTTSMNGYGSAAMSNLG--GSPTFLNGSAANSPYAIVPSSPTMASS-TSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPP-PTCTSTNGNSLQ---------------AISGMIVPPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63398-1", "uniprot_id": "COE1_RAT", "id": "Q63398-1", "name": "Transcription factor COE1", "aln": "---------------------------------------------------------------------MFG----------------------------IQESIQRSGSSMKEEPLG-SGMNAVRTWMQGAGVLDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE---------------------------AAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQ-GFTRN-SSSVSPHG-YVPSTTPQQTNYNS-VTTSMNGYGSAAMSNLG--GSPTFLNGSAANSPYAIVPSSPTMASS-TSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPP-PTCTSTNGNSLQ---------------AISGMIVPPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B8M6-1", "uniprot_id": "A0A8M2B8M6_DANRE", "id": "A0A8M2B8M6-1", "name": "Transcription factor COE4", "aln": "---------------------------------------------------------------------MFG----------------------------IQESIQRCGSILKEEPIG-AGMNTVRTWIQGAGVLDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTSFVGFVEKEKETTGEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQPIIYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVEGHVLAVSDNMFVHNNSKHGRRARRLDPSEGT--------------------PSYLEHAAAPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGSMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVESLYGMPHNNQEIILKRAADIAEALYNVPRSHNQLTGLTNSSVHTSMMGGNSFTGQLAVNVSESSQGGNQ-GFGRN-TSSVSPHG-YVPSSTPQQSSYST-VSTSMNGYGNSGMTNLT--GSPNFLNGSAANSPYAIVPSSPTMASS-TSLPSNCINSSGIFSFSPANMVSAVKQKSAFAPVIRPQSSPP-PTCTSTNGNGVQDQSFVDSN-KYSTASALQGLAFS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IWI1-1", "uniprot_id": "COE1A_DANRE", "id": "A0A0R4IWI1-1", "name": "Transcription factor COE1-A", "aln": "---------------------------------------------------------------------MFG----------------------------IQDSIQRSGSSMKEEPIG-AGMNAVRTWMQGAGVLDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTSFVGFVEKEKESTGEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGT--------------------PSYLEHAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYNVPRGHNQLPGLTNSSVHSGMMGVNSFHSQLAVNVSDSTQAANQ-GFSRN-TSSVSPHG-YVPSTTPQQSSYST-VSTSMNGYGNAGMTTLG--GSPNFLNGSAANSPYAIVPSSPTMASS-TSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQASPP-PTCTSANGNGLQ---------------VIPGMIVPPM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9H4W6-1", "uniprot_id": "COE3_HUMAN", "id": "Q9H4W6-1", "name": "Transcription factor COE3", "aln": "---------------------------------------------------------------------MFG----------------------------IQENIPRGGTTMKEEPLG-SGMNPVRSWMHTAGVVDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNNEKTNNGIHYKLQLLYSNGVRTEQDLYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTA-------------------PSYLENAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQIPTLGNNPAHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRN-TSSVSPRG-YVPSSTPQQSNYNT-VSTSMNGYGSGAMASLGVPGSPGFLNGSSANSPYGIVPSSPTMAASSVTLPSNCSSTHGIFSFSPANVISAVKQKSAFAPVVRPQASPP-PSCTSANGNGLQ---------------AMSGLVVPPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08791-1", "uniprot_id": "COE3_MOUSE", "id": "O08791-1", "name": "Transcription factor COE3", "aln": "---------------------------------------------------------------------MFG----------------------------IQENIPRGGTTMKEEPLG-SGMNPVRSWMHTAGVVDAN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNNEKTNNGIHYKLQLLYSNGVRTEQDLYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTA-------------------PSYLENAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQIPTLGNTPAHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRN-TSSVSPRG-YVPSSTPQQSNYNT-VSTSMNGYGSGAMANLGVPGSPGFLNGSSANSPYGIVPSSPTMAASSVTLPSNCSSTHGIFSFSPANVISAVKQKSAFAPVVRPQASPP-PSCTSANGNGLQ---------------AMSGLVVPPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT68-1", "uniprot_id": "D3ZT68_RAT", "id": "D3ZT68-1", "name": "Transcription factor COE2", "aln": "---------------------------------------------------------------------MFG----------------------------IQDT-LGRGPVLKEKSLG-AEMDSVRSWVRNVGVVDAN-------VAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE-----------------------------ATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQIPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQ-GYIRN-TSSISPRG-YSSSSTPQQSNYST-SSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSS---------STSSILPFSSSVFP-AVKQKSAFAPVIRPQGSPS-PACSSGNGNGFR---------------AMTGLVVPPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08792-1", "uniprot_id": "COE2_MOUSE", "id": "O08792-1", "name": "Transcription factor COE2", "aln": "---------------------------------------------------------------------MFG----------------------------IQDT-LGRGPALKDKSLG-AEMDSVRSWVRNVGVVDAN-------VAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE-----------------------------ATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQIPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQ-GYIRN-TSSISPRG-YSSSSTPQQSNYST-SSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSS---------STSSILPFSSSVFP-AVKQKSAFAPVIRPQGSPS-PACSSGNGNGFR---------------AMTGLVVPPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAK2-1", "uniprot_id": "COE2_HUMAN", "id": "Q9HAK2-1", "name": "Transcription factor COE2", "aln": "---------------------------------------------------------------------MFG----------------------------IQDT-LGRGPTLKEKSLG-AEMDSVRSWVRNVGVVDAN-------VAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE-----------------------------ATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQ-GYIRN-TSSISPRG-YSSSSTPQQSNYST-SSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSS---------STSSILPFSSSVFP-AVKQKSAFAPVIRPQGSPS-PACSSGNGNGFR---------------AMTGLVVPPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O93375-1", "uniprot_id": "COE2_DANRE", "id": "O93375-1", "name": "Transcription factor COE2", "aln": "---------------------------------------------------------------------MFE----------------------------SQDHSIRTITELKVRTFE-EEMDPVRSWVRNVGVIDAN-------IAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRNGQPVEVERTSFVDFVEQDKTG--EKTNNGTHYKLQLLYSNGVRTEQDLYARLIDSVTKQPISYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVCVDGPVLAISDNMFVHNNSKHGRRSRRMDPNETV---------------------ENNMEYATPCIKAISPSEGWTTGGAMVIVIGENFFDGLQVVFGSMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYT-ALNEPTIDYGFQRLQKLIPRHPGDPDKLAKEMLLKRAADVVESLYGNTTSNQDMLLKRAADIAEALYSVPRPHSQLQAMPSSPVHGSVMGLSSYPTQLGVSIGEPGQTSGQ-GYTRN-SSSLSPRG-YPSSSTPQQSAYG--SNGGMS-YGAVPMSSLGVSGSPGFNSASPNSSPYAIMPSSP-PGSS---------SSSSLLPFSS--FPSSTKQKSAFAPVLRPQGFPHHPSAKTSGGTSFR---------------AMTGLVVPPM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZW79-1", "uniprot_id": "D3ZW79_RAT", "id": "D3ZW79-1", "name": "Transcription factor COE4", "aln": "MARARGQAPGSGGRRRPRRGGAGTGPRGDSAGLLLLLLQVLPPGAAAGPGRRGTRGSGGGCVCWPSAGPAFPRDARLLLLLPPRPPPSPPPTSTAAASPSRMDALPRGGLHLKEEPLLPSSLGSVRSWMQSAGILDSS-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLAMYDRQGQPVEVERTAFIDFVEKDREPGTEKTNNGIHYRLRLVYNNGLRTEQDLYVRLIDSMSKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDRKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE----------------------------AATPCIKAISPGEGWTTGGATVIIIGDNFFDGLQVVFGNVLLWSELITPHALRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLAEALYGVPNSNQELLLKRAADVAEALYSAPRAPAPLGPLAPSHPHPAVVGINAFSSPLAIAVGDATP--EP-GYARS-CGSASPR--FAPSPGSQQSSYGSGLGAGLGSYGAPGVTGLGVPGSPSFLNGSTATSPFAIMPSSPPLAAASSMSLPAAAPTTSVFSFSPVNMICAVKQRSAFAPVLRPPSSPS-QACPRAHREGLPDQPFEDTDKFHSAARGLQGLAYS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4J2-1", "uniprot_id": "COE4_MOUSE", "id": "Q8K4J2-1", "name": "Transcription factor COE4", "aln": "---------------------------------------------------------------------MFP----------------------------AQDALPRGGLHLKEEPLLPSSLGSVRSWMQSAGILDSN-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLAMYDRQGQPVEVERTAFIDFVEKDREPGTEKTNNGIHYRLRLVYNNGLRTEQDLYVRLIDSMSKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDRKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE----------------------------AATPCIKAISPGEGWTTGGATVIIIGDNFFDGLQVVFGNVLLWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLAEALYGVPSSNQELLLKRAADVAEALYSAPRAPAPLGPLAPSHPHPAVVGINAFSSPLAIAVGDTTP--EP-GYARS-CGSASPR--FAPSPGSQQSSYGSGLGAGLGSYGAPGVTGLGVPGSPSFLNGSTATSPFAIMPSSPPLAAASSMSLPAAAPTTSVFSFSPVNMICAVKQRSAFAPVLRPPSSPS-QACPRAHREGLPDQPFEDTDKFHSAARGLQGLAYS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQW3-2", "uniprot_id": "COE4_HUMAN", "id": "Q9BQW3-2", "name": "Transcription factor COE4", "aln": "---------------------------------------------------------------------MFP----------------------------AQDALPRSGLNLKEEPLLPAGLGSVRSWMQGAGILDAS-------TAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLAMYDRQGQPVEVERTAFIDFVEKDREPGAEKTNNGIHYRLRLVYNNGLRTEQDLYVRLIDSMSKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDRKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE----------------------------AATPCIKAISPGEGWTTGGATVIVIGDNFFDGLQVVFGNVLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGCPGRFVYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLAEALYGVPGSNQELLLKRAADVAEALYSTPRAPGPLAPLAPSHPHPAVVGINAFSSPLAIAVGDATPGPEP-GYARS-CSSASPRG-FAPSPGSQQSGYGGGLGAGLGGYGAPGVAGLGVPGSPSFLNGSTATSPFAIMPSSPPLAAASSMSLPAAAPTTSVFSFSPVNMISAVKQRSAFAPVLRPPSSPP-QACPRAHGEGLPDQSFEDSDKFHSPARGLQGLAYS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56721-1", "uniprot_id": "COLL_DROME", "id": "P56721-1", "name": "Transcription factor collier", "aln": "---------------------------------------------------------------MEWGRKLYP--------------------------SAVSGPRSAGGLMFGLPPTAAVDMNQPRGPMTSLKEEPLGSRWAMQPVVDQSNLGIGRAHFEKQPPSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPEKLQKEIILKRAADLVEALY----------------------SMPRSPG------------GSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGS--YGATAASAAVAATANG--YAPAPNMGTLSSSPGSVFNSTSMSAVS----------STWHQAFVQHHHAATAHPHHHYPHPHQPWHNPAVSAATAAAV-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :. * : . . **.:.:.*********************:*:*** ***:*:***:*:.*:*:: ***** :*:*:*:* ** * ***::.*****::**.* ****:*************:******::*********************************.*************:** * *:* :**:***************::*:*..* : ********.******** **::*:********:**.:*:******.**:*************************** ****:*. ****************:********::* **::******:.*:** . ** . * .:: *.: : : .: * .* **: : .*. . :: . . . : :* .: ** .:. *:. . : : .* :.: : :. :* * :. ", "identical_positions": 277, "similar_positions": 112, "identity": "37.38%" }, { "cls_id": "homologset.agr.FB:FBgn0001321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35370-1", "uniprot_id": "O35370_RAT", "id": "O35370-1", "name": "Thrombomodulin", "aln": "-------------------MLGVFLLGVLAPAG------------LGISALAKLQPKGSQCVGNECFALFQ---------------------DPVTFLD-----ASQACQRLQGHLMTVRSSVAADVISLLVS-DSSMDSR-PWIGLQLPQGCGDPV-HLG---PLRGFQWVTGDNHTSYSRWARPNDQSPPLCG-------PLCVTVSTATEAAPGEP-------AWEEKPCENETKG--------FLCEFYFAAFCRPLRVNTRDPEGAHISSTYNTPLGVSGADFQTLPIGSSATVAPFGLELVCRALPGTSEGHWTREVTGAWNCSVENGGCEYMCNRSANGPRCVCPSGGD-----LQADGRSCAKPVAQLCNELCQHFCVNNSDVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCSNTEGGFECRCYDGYELVDGECVEQLDPCFRSKCEYQCQP---VNSTHYNCICAEGFAPKLDDPDRCEMFCNETSCPADCDPNSPSFCQCPEGFILDEGSICTDIDECSQGECLTNECRNLPGSYECICGPD---TALAGQISKDCDPIPVLEDS-EDGGSGEHPSSNPTVVSSTVPPSARPMHSGVLIGISIASLSLVVALLALLCHLRKKQGTARAELEYKCTSSAKEVVLQHVRTDRTLQKF----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15306-1", "uniprot_id": "TRBM_MOUSE", "id": "P15306-1", "name": "Thrombomodulin", "aln": "-------------------MLGIFFLGVLAPAS------------LGLSALAKLQPTGSQCVEHECFALFQ---------------------GPATFLD-----ASQACQRLQGHLMTVRSSVAADVISLLLS-QSSMDLG-PWIGLQLPQGCDDPV-HLG---PLRGFQWVTGDNHTSYSRWARPNDQTAPLCG-------PLCVTVSTATEAAPGEP-------AWEEKPCETETQG--------FLCEFYFTASCRPLTVNTRDPEAAHISSTYNTPFGVSGADFQTLPVGSSAAVEPLGLELVCRAPPGTSEGHWAWEATGAWNCSVENGGCEYLCNRSTNEPRCLCPRDMD-----LQADGRSCARPVVQSCNELCEHFCVSNAEVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCVNTKGGFECFCYDGYELVDGECVELLDPCFGSNCEFQCQP---VSPTDYRCICAPGFAPKPDEPHKCEMFCNETSCPADCDPNSPTVCECPEGFILDEGSVCTDIDECSQGECFTSECRNFPGSYECICGPD---TALAGQISKDCDPIPVREDTKEEEGSGEPPVS-PTPGSPTGPPSARPVHSGVLIGISIASLSLVVALLALLCHLRKKQGAARAELEYKCASSAKEVVLQHVRTDRTLQKF----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07204-1", "uniprot_id": "TRBM_HUMAN", "id": "P07204-1", "name": "Thrombomodulin", "aln": "-------------------MLGVLVLGALALAG------------LGFPAPAEPQPGGSQCVEHDCFALYP---------------------GPATFLN-----ASQICDGLRGHLMTVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPK-RLG---PLRGFQWVTGDNNTSYSRWARLDLNGAPLCG-------PLCVAVSAAEATVPSEP-------IWEEQQCEVKADG--------FLCEFHFPATCRPLAVEPG-AAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAA-----LQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQP---LNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPD---SALARHIGTDCDSGKVDGGD---SGSGEPPPS-PTPGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVVLQHVRTERTPQRL----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH23-1", "uniprot_id": "Q9VH23_DROME", "id": "Q9VH23-1", "name": "", "aln": "MALSSRVLCLRLQHHLLLVILTIFLLCPAASAQNEEEDGPYRGKYLGKLNSYHHQVSGDVYAVNEYTFLIVGFNYDGNGADTFFWSGASNRPGPQGFIVPDEYGKTNILDRYHNKDFTLTLPDRKKITEIKWLAVYDLSSQNNFGDVYIPEEFDPPMSQLGGTFSKRSHNVSSSSVEILDSKTIRIKDFTYDGRGKRTFFWTGVGPQPSSRGSKLPDERGYLDPIRQYNKETIELELPGDKTIFDIDWISVYDVADNENYGHVLFNDKLNVPPSLVKVTPFEFSLPNCRQLHKDMQVSWEVFGPQITFQLSGQVGGNDYMSFGISGSDVSSQMIGSDVVVAYIDDIRGYTVDYNITSLAPCVQVLGQNKGVCRDDVVGGLDSFQLNTYSRKDGINTISFRRTLKSSDDGDKEIFLDRSNYVIWAFGPLDSNNEPAFHTYYPKSDIVIDFNTTEPVNDCFAFTKRAETTNPPVWERTRITDATVRTFNAYLGPSGGLRGYQGLTNHVSSGLAWYINGYMIPELYLKR-GLTYTFKVRGGNNPHSPEHYHPLVITDDPQGGYDRLSDAKQSEIRVLAGVEFTRRGRPKPTAAGPLCLSRYPQNSDRRLDDNFPTFKKFNRSLITECVEGEPALLEITPNITWPDTVYYNSFTHGNMGWKIHIVDSYTNLKSGSMGLSWSLCIILLPWLVLQN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::.* * * ** . * *. . :: * .* *: :: : :.: :*: . .: .: .:. : .: :* . * :** . *..: :.. . *: * . * : *: *.* :::: * : * ::. : .. . * . * . **: .: : * . ..: :* :: . ..: .. : * : *.: . . :*. *:. : . * .. . * : . : : * .: :* . . *.: .*. . ::* : .* :: ** . . : . * . * . . . : . * :. . ** :: * * . :. . : : : : * * * .* .. . . .:* * . * .. . .: .: *** : :: : . .: : . .:* .:.. . : ", "identical_positions": 63, "similar_positions": 167, "identity": "9.13%" }, { "cls_id": "homologset.agr.FB:FBgn0001324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFY8-1", "uniprot_id": "A0ABK0LFY8_RAT", "id": "A0ABK0LFY8-1", "name": "", "aln": "MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLAILAKKELPLAKSGVPQVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLVKISDFYHM--------------------------------------------------------------------------------------------ASST----GDGPVPVPP------------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLSWILDVLEKIR---PVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSP--NLLAAHSPHMIIGANNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKIANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWA---NQNKDNQEVAP-------NDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEVEAERCGE-SEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPSLSDPNSE-CEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTAS-TGLRSPAGENSDEHYSKDHE----MKMEEHAVMAHMGLGSGTTNIFDEVDKSDFKSDFGSEFPIFSPMPGESCENINPSLSRRMSGNGEKLGKREKPRELIFPSNYDLLRHLQYATHFPIPLDE----SSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTESG----------------VGDEGQKARKNKQEVFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFG---DLFSSACSKVKQTIYNNVMPANSN-LRWDPDFMMDFIENPS-ARSINYSMLGKV---LNDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACG-----DADAEPGARMTCRLLLHLFR---APQACFFPQATGKP---FPG----IRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTL---------------KNEDFSMRGLR-------RDGSAEDAWATSQNSKPYGKSIS-------------IETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASSSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ---DDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSTASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNP-APLSWAWFGTVRVDRRVIKYEEQHHFLLYHTHTMPKPRSYYLEPLPLPPEEEEEEPTSPVSQEPERKSAELSDHGKSAADEEKKTKGRKRKTKSSSRIDEYQQTNIYRLPPNYS-----PMSSQMMHHTQPALWGYNLVSQPQQPSFFLQNQSLNAGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMLQPPSLHAVTSQQQLLQMKLLQ---QQQQQQQQ-----------------QQQQQQQQRLLRQAQTRPFQQGQPGDQAALFTAQARPSPQLPQYPG---------LQQQAQTMPQGYTMYGTQMPLQQAAQQQPGGVVLSPSYSSRAYPAAH--SSPALMERLRQLQQQPGGYVQQQAS-PYLQPVAGSQR-----------------LNHQALQQSPLVG---------------------------------GAIDAVLTPAHPNLPSVPLAQD---PMRPRQQQVRQQQ---------------------------------RLLQ--------------------------------MQQPQQAPQ---------------------------------------------------------PQQPSQ---PQSQALGLQAMQP------------QQPLFPRQG--------------LQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPCAHPSHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM9-1", "uniprot_id": "MD12L_MOUSE", "id": "Q8BQM9-1", "name": "Mediator of RNA polymerase II transcription subunit 12-like protein", "aln": "MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLAILAK-----------KVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLVKISDFYHM--------------------------------------------------------------------------------------------ASST----GDGPVPVPP------------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIR---PVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSP--NLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKISNPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWA---NQNKDNQEVAP-------NDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGE-SEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPALSDPNSE-CEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTAS-TGLRSPAGENSDEHYSKDHD----MKME-----------------------------------IFSPMPGESCENINPSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDE----SSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKGTTESG----------------VGDEGQKARKTKQEVFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFG---DLFSSACSKVKQTIYNNVMPANSN-LRWDPDFMMDFIENPS-ARSINYSMLGKI---LNDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACG-----DADAEPGARMTCRLLLHLFR---APQACFFPQGTGKP---FPG----IRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTM---------------KNEDFGMRGLR-------RDGNAEDAWATSQNSKSYGKSIS-------------IETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASNSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ---DDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSSASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNP-APLSWAWFGTVRVDRKVIKYEEQQHFLLYHTHTMPKPRSYYLEPLPLPPEEEEEELTSPVSQEPERKSAELSDQGKATADEEKKTKGRKRKTKSSSRIDEYQQTNLYRVPPNYS-----PMSSQMTHHPQPALWGYNLVSQPQQPSFFLQNPSLNPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMLQPPSLHAVTSQQQLLQMKLLQ---QQQQQQQQ-----------------QQQQQQ--RLLRQAQTRPFQQGQPGDQAALFTAQARPSPQLPQYPG---------LQQ-AQTMPQGYTMYGTQMPLQQAAQQQPGGVVLSPSYNSRAYPAAH--SSPALMERLRQLQQQPSGYVQQQAS-PYLQPVAGSQR-----------------LNHQALQQSPLVG---------------------------------GGIDAVLTPAHPNLPSVPLPQD---PMRPRQQQVRQQQ---------------------------------RLLQVWGR---------------------------EMQQPQQAPQ---------------------------------------------------------PQQPSQ---TQSQALGLQAMQP------------QQPLFPRQG--------------LQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPCAHPSHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YW9-1", "uniprot_id": "MD12L_HUMAN", "id": "Q86YW9-1", "name": "Mediator of RNA polymerase II transcription subunit 12-like protein", "aln": "MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLSILAK-----------KVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLAKISDFYHM--------------------------------------------------------------------------------------------ASST----GDGPVPVPP------------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIR---PMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSP--NLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWA---NQNKDNQEVAP-------NDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGE-SEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSE-CEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTAS-TRPRSPVGENADEHYSKDHD----VKME-----------------------------------IFSPMPGESCENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDE----SSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETG----------------VGDEGQKARKNKQETFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFG---DLFSSACSKVKQTIYNNVMPANSN-LRWDPDFMMDFIENPS-ARSINYSMLGKI---LSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACG-----DADAEPGARMTCRLLLHLFR---APQACFLPQATGKP---FPG----IRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSL---------------KNDDFTMRGLR-------CDGNADDIWTASQNPKSCGKSIS-------------IETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLNN-SSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ---DDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKK--QGLQVSTKQKVSPWDLFEGQKNP-APLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHPMPKPRSYYLQPLPLPPEEEEEEPTSPVSQEPERKSAELSDQGKTTTDEEKKTKGRKRKTKSSSRVDEYPQSNIYRVPPNYS-----PISSQMMHHPQSTLWGYNLVGQPQQPGFFLQNQSLTPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMKLLQ---QQQQQ----------------------------RLLRQAQTRPFQQGQPGDQAALFAAQARPSPQLPQYPG---------LQQ-AQTMPQGYTMYGTQMPLQQTSQQQAGSVVLSPSYNSRAYPAAH--SNPVLMERLRQIQQQPSGYVQQQAS-PYLQPLTGSQR-----------------LNHQALQQSPLVG---------------------------------GGIDAVLTSAHPNLPSVPLPQD---PMRPRQPQVRQQQ---------------------------------RLLQMQQP---------------------------QQPQPQQPPQ---------------------------------------------------------PQQSSQ---SQSQTLGLQAMQP------------QQPLFPRQG--------------LQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPYGHPSHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A096MKF8-1", "uniprot_id": "A0A096MKF8_RAT", "id": "A0A096MKF8-1", "name": "", "aln": "MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDLAGTKPLTHLAK-----------KVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNTADPFTEWTQIITKYLWEQLQKMAEYYRP--------------------------------------------------------------------------------------------GPAGSGVCGSAIGPLPH------------DVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIR---PGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLD------GVNSHSSHVISAQSTSSLPT-TPAPQPPTSNTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWH-YSLTDSRI-KTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGL---GPSKDGHEISS-------DDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGE-SEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSE-SERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGTPGPRPPSPFDDPADDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFS-------LFSPTMPCEGKG--SPSPEKPDVEKDVKPPPKEK-IEGTLGILYDQPRHVQYATHFPIPQEE----SCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFVFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFG---ELFSDFCSKVKNTIYCNVEPSESN-MRWAPEFMIDTLENPA-AHTFTYTGLGKS---LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACS-----EQDSEPGARLTCRILLHLFK---TPQLNPCQSDGNKP---TVG----IRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAEL-----------------------KGSGFTVPGGT-------EELPEEEGGGGSSGRRQGGRNIS-------------VETASLDVYAKYVLRSICQQEWVGERCLKS---LCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDSEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNT-------EMNSLLENIAKATIEVFQQSAETGSS---------SGSTASNMPSSSK----AKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYL---DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKE--GLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEE--PPAPALLEPEKKAPEPPKTDKPGTAPPSTEERKKKSTKGKKRSQPATKSEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMG-LYTQNQPLPAGGPRVDPY-----RPVRLPMQKLPTRPTYPGVLPTTMTTVMG-LEPSSYKTSV---YRQQQP---------------------------TVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYG----------LQS-SQ----GYTSYVSHVGLQQHTGPAGT--MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAP-TYGHGLTSTQR-----------------FSHQTLQQTPMMG---------------------------------TMTPLSAQGVQAGVRSTSILPE---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-YHIRQQQQQQQILRQQQQQQQ---------------------------QQQQQQQQQQ---------------------------------------------------------QQQQQQPQQQQPHQQQQQAAPP-------QPQPQSQPQFQRQG--------------LQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AGH6-1", "uniprot_id": "MED12_MOUSE", "id": "A2AGH6-1", "name": "Mediator of RNA polymerase II transcription subunit 12", "aln": "MAAFGILSYEHRPLKRLRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLSDTGRRKSLMNQKDNFWLVTARSQSAINTWFTDLAGTKPLTHLAK-----------KVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKKKNTADPFTEWTQIITKYLWEQLQKMAEYYRP--------------------------------------------------------------------------------------------GPAGSGGCGSTIGPLPH------------DVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIR---PGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLD------GVSSHSSHVIAAQSTSSLPT-TPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWH-YSLTDSRI-KTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGL---GPSKDGHEISS-------DDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGE-SEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSE-SERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPTDDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFS-------LFSPTMPCEGKG--SPSPEKPDVEKEVKPPAKEK-IEGTLGILYDQPRHVQYATHFPIPQEE----SCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFG---ELFSDFCSKVKNTIYCNVEPSESN-MRWAPEFMIDTLENPA-AHTFTYTGLGKS---LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACS-----EQDSEPGARLTCRILLHLFK---TPQLNPCQSDGNKP---TVG----IRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAEL-----------------------KGSGFTVPGGT-------EELPEEEGGGGSSGRRQGGRNIS-------------VETASLDVYAKYVLRSICQQEWVGERCLKS---LCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNT-------EMNSLLENIAKATIEVFQQSAETGSS---------SGSTASNMPSSSK----TKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYL---DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGERQSDSLEKVHQLLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKE--GLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEE--PPAPALLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKNEDYGMGPGRSGPYGVTVPPDLLHHANPGSISHLSYRQSSMG-LYTQNQPLPAGGPRVDPY-----RPVRLPMQKLPTRPTYPGVLPTTMSTVMG-LEPSSYKTSV---YRQQQP---------------------------TVPQGQRLRQQLQAKIQSQGMLGQSSVHQMTPSSSYG----------LQT-SQ----GYTSYVSHVGLQQHTGPAGT--MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAP-TYGHGLTSTQR-----------------FSHQTLQQTPMMG---------------------------------TMTPLSAQGVQAGVRSTSILPE---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQQMLRQQQQQQQ---------------------------QQQQQQQQQQ---------------------------------------------------------QQQQQQ-QQQQPHQQQQQAAPP-------QPQPQSQPQFQRQG--------------LQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93074-1", "uniprot_id": "MED12_HUMAN", "id": "Q93074-1", "name": "Mediator of RNA polymerase II transcription subunit 12", "aln": "MAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVSFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINTWFTDLAGTKPLTQLAK-----------KVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKKR-HVDPFMEWTQIITKYLWEQLQKMAEYYRP--------------------------------------------------------------------------------------------GPAGSGGCGSTIGPLPH------------DVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIR---PGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLD------GVSSHSSHVISAQSTSTLPT-TPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWH-YSLTDSRI-KTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGL---GPSKDGHEISS-------DDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGE-SEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSE-SERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFS-------LFSPTMPCEGKG--SPSPEKPDVEKEVKPPPKEK-IEGTLGVLYDQPRHVQYATHFPIPQEE----SCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFG---ELFSDFCSKVKNTIYCNVEPSESN-MRWAPEFMIDTLENPA-AHTFTYTGLGKS---LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACS-----EQDSEPGARLTCRILLHLFK---TPQLNPCQSDGNKP---TVG----IRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAEL-----------------------KGSGFTVTGGT-------EELPEEEGGGGSGGRRQGGRNIS-------------VETASLDVYAKYVLRSICQQEWVGERCLKS---LCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNN-------EMNSLLENIAKATIEVFQQSAETGSS---------SGSTASNMPSSSK----TKPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYL---DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKE--GLQVSTKQKISPWDLFEGLKPS-APLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEE--PPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIG-LYTQNQPLPAGGPRVDPY-----RPVRLPMQKLPTRPTYPGVLPTTMTGVMG-LEPSSYKTSV---YRQQQP---------------------------AVPQGQRLRQQLQ---QSQGMLGQSSVHQMTPSSSYG----------LQT-SQ----GYTPYVSHVGLQQHTGPAGT--MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAP-TYGHGLTSTQR-----------------FSHQTLQQTPMIS---------------------------------TMTPMSAQGVQAGVRSTAILPE---QQQQQQQQQQQQQQQQQQQQQQQQQQ-------YHIRQQQQQQ-ILRQQQQQQQ---------------------------QQQQQQQQQQ---------------------------------------------------------QQQQQQ-QQQHQQQQQQQAAPP-------QPQPQSQPQFQRQG--------------LQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2QCI8-1", "uniprot_id": "MED12_DANRE", "id": "Q2QCI8-1", "name": "Mediator of RNA polymerase II transcription subunit 12", "aln": "MAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNSSKISSNFSSIIAEKLRCNTFPDTGKRKPQVNQKDNFWLVTARSQSSINNWFTDLAGTKPLTQLAK-----------KVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAITENKMKKRHVIDPCIEWTPIITKYLWEQLQKVAEFYRQ--------------------------------------------------------------------------------------------SPSQ--GCGSPLPAPPA------------EVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIR---PGEDELLRLLLPLLLQYSGEFVQSAYLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPP-TPTSQPAGGNQPQTPFTDFYICPQHRPVVFGLSCMLQSIVLCCPSALVWH-YSLTDSRN-KTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRWSFDKCQETTAGFTISRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGS---GQSKDGHEMSP-------DDDAVVTLLCEWAVSCKRSGPHRAMVVAKLLEKRQTEIEAERCGE-SEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVLTEPGNE-SERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHLPRPRSPSDEPSDESERKDQDAGSSVKMEDTGMSESMEIDHNSSANFDEM--------------FSPPMHCESKG--SPSPEKQAQEQESKSTAKDKGMDPAFPLVYEQPRHIQYATHFPIPQEE----SASHECNQRLVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAET-----------------GGEEGQKRKRSKPEAFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQLLNELSLVEAELLLKSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFG---EIFSEFCSKVKNSIYYNIDPSDSN-MLWDQMFMIDAITNPT-AHNLNHSMLGKITNELNDSPANRYSFVCNVLMDVCVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNGNCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLVRCVAIPSLLNAACS-----EQDSEPGARLTCRILLHLFR---TPQRNPCPQDGTKSDKSIVG----IRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAEL-----------------------KGSGFSHPAGL-------DDIGEDDMGS----KKSGGRNVS-------------IETASLVVYAKYVLKSICHQEWVGERCLKS---LSEDSSALQDPVLVNIQAQRLLQLICYPHRQLDSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNN-------ELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVSGSSVSNSNSASK----LKPVLSSSERSGVWLVAPLIGKLPTSVQGHVLKAAGEELEKGQHLGPSSRKERDR-----QKQKSMSLLSQ-------------------QPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQ---DDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSESLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFE----KE--GLQVSTKQKISPWDVFEGLKHS-APLSWGWFGTIRVDRKVTKFEEQQRLLLYHTHIKPKQRSYYLAPLNLPQEEEE--PLTPVPPEPDKKLDTAKVEKSVSNVPTKKKKKKPASTVKQEDYKPHNTVMQYAPG----------MTPDLPLSMGQTNMSYRMGYQAPMN-MYAQNQPLPPGGPGLEPP-----FRPRVPMNKMPPRPNYT--MPNMQTAGMGNLMGMEKQYQM---NYKPMP---------------------------NMAQGQMLRHQLQG---HNHLIGQQ-IRQVTPNPQYSS---------MQP-AQNIPQGYTSYGSHMGMQPHPSQTPG--MVPNSYGNQGFQTGHPATNPTMVDSIRQMQQRP-GYVHQQAPAAYGHTIQSTQR-----------------FPHQSMQQTPMMHG-------------------------------LAQSHLGVQGIHPNMRPNQMMEQ---QQQQQQQQQQQQQQQQQVHQQQQHIRQGPVFR--PQQQQQVQQQVQQQVQQQQV---------------------------QQQQVQQQVQ---------------------------------------------------------PQQVQQQQVQQQQQQQVSAAQPPAQALGMQALPPQQPMFQRQG--------------MQQTQQQQQTAALVRQLQQQLSSTQPAQNNSSYY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW47-1", "uniprot_id": "MED12_DROME", "id": "Q9VW47-1", "name": "Mediator of RNA polymerase II transcription subunit 12", "aln": "--MLSMLQ-EKRPLKRTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLS-DEFGTAHNSNVNASKVSAFFSGVLAKKEELMTLPDTGRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAK-----------RAPSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTGNMIKFMKELLPKLQEYYQQNHDKSSSNGTTSGSLTAAGNGPASNGSTGTSSINSVTGSSASTNVIPVPSMASPLPPIHSPANGQQAAPGGGVNAGSVMPTTGSLGGVVGGPGSSVVGGAAGAGAAVPPGSTISGIGSQFEDSRNALKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEPLKKLVLSFALQYMHDFVQSERLCRKMAYIVSKKLAQLLN-------------TVVEQQTIKELDE-----PKLQQDPYELALQEQMSCPHHRDIVLYLSTILQIITIECPTALVWSGIAAHRAPSSLLGSPLDHLPLAPSVLPMPTRCPRTNHEIRRQLRAAESDIVLRTQHAEQRWFAAKWLSAGKNQYTS-VLATLDHLDTHCFDRMEHNNSIDTLYAQIFPSPTVSRRREEDQVEPRPPYEPKQDKDTVRILCEWAVSGQRWGEHRAMVVAILLDKRQIDVTSTPADQQSSDKDDKDSLASGAGLIDGLPVFQHVLMHFLDHDAPVLDEHVSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESVLVIKSGTTATKTSPPPPAPPP-TTTHGFDDDGFGGGLDFKHNEFD--------------------DSNVDDDLDKLVQNIKEKGQQHEAPDSPKIGPPGDGETNPGGSISRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEIGKLFTKKFSIDVA------------------AAGHVKKHSRNEFN--FEATTSKCQQMAYFDQHVVTAQCAANVLEQLNGFALGNNNYLPVQEHVAFLFDLMELALNIYSLLELCDSLLKELPEVEHQLQLKKSNLVRSYTTSLALYIVSILRRYHSCLLLSPEQTLSVFEGVCRTIRHVSNPSECTSAERCIIAYLSDLHESCVLLQGKEQSTEYYQQLQCIKRFKDIFNTPEQLDLPPQGYNPLLLQELFMAPRRGGKLDPHWLGTL----HESPANVYSFVSNALIAVCR-ETDNERLNDVALACAELTASCNVLSEEWIYALQSLCSGSK--SPRYPHLGGQVDIGQLKTHNALAVFVCILVARHCFSLADFVSKFALPTLARSVSAGGAELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVSTSPNPLHAVGNDFSIRLSCDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPLASGSGTSSGGLGGAFGSGKRSGFNTPVHPGSTPKSNEQRPADLSQILGTSDLQLGSSLTSEPEALQQPSVGGMEQISLLEFAQAVLKQICAQEHVLERCLKN---AEQLCDMIIDEMLTAKQAQRVLHMICYPEPEFN-IISELDQRSMIVRILENLGQWTLRISWLDLQLMYRQSLSNN-----AELNVWLDTVARAAIDVFHMEEVVLPG---------------AVKATHK------------PKPSTWLVAPLIAKLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGLGGVPARNKKMPLDYQPFLGLILTCLKGQDEYKENLLVSLYAQLSQCLQSFAELDTIGGIDEPQAREEILDALQLRFSLVGGMFEAIQKNSTPTTDWAILLAQLVCQGVVDLSCNRELFTTVVDMLATLVHSTLVSD-----------DERHYMNLMKKLKKEIGEKNNASIRVIRQLLPLYKQPTEVIACEHSG--MDTKGNKICDID---KKQ---LRISDKQRISVWDILEGHKNP-APLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEPLPLPPEDIEPVPEKICIKDEMKADTPSSVDQSPSAVVGGTGRGRGKGTTTRKRKPKNPKTPPVVNTQQQQPQ--LAQQPQQPQNVQQQQLQQQQQQQQHMQQQHMQQQQMQPNQMGQMPMNMPMNMQQFAPNPNNMMQQNAMLQQQQQQQMQQMGNNPMQQQLNVGGGNGQPNPQMNFMQQGPGGGGAGPQGMPGQQQQWHNAPQQQQPPQPYHNQYAPHQQNMQSNRIERPPLNANSKQALSQMLRQRQPFQQQAQQGPGGGFNPMQQQPQASQQQPGPQQQMNPNQMRQQQMNPQQNPQSVAAFNAMQQQPQQNAQQQQMNPNQQQQQQFMRGGNMRPGMAPNQMNQMNMGGQGMSQNPMMQQQIPQNMVGMVNPNANQMMQSGGAQGGNGVGVGVGVGVGGAGNNPNMGMGGMPQQGMIQQQPQQQPQQQVQFQNFQNQYQQQQQQGMQQQGGGAGVGVGVGMAPNQQQQQQANMMGNFNPQMQQGNRNNPDFMAAAAVAQQQQQQQQQQRVVPGGMMAGNRNQYMNQAPNVTMSTMMGPGPGGVVGQVPPYARQQSAGGGKPGVLNTQQQFQQQQQQQQQLRHQMMQLQGMG---GGAGGGMGAGPQQGGGAVGGGAGGGMVPQQQSMNQQQTPNLVAQLQRQNMMGQQQYQPPPY------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:*. *:***** ******:****.**:*****. ***:**.. *..: **.*:*:* .*.:*:.: **.::*:* . *: ***::* :* ***:* *:.* :.::. **.****.*** *** :.* :.***::* *.: * : *::*:**::.** :::* * **: ** *** ::: * * *: ::*: ..: .. . * : . *:: *.* .:*: .*:::.:*:::*:*.*:*: ::*:* . :: * :*:*.: *:* :**** *.*::**: :::* *. : . : . . .: : *.:* :* ** :** : : **:**** : ***** * :*** **** . .:::* :: *.:* * : .* ** * .: . . ** **: ** *.*:: : .**:::* :** . :: .:: . :*. .* :******* :* * ****.** **:*** :: : ..: *. *:* *::*.: *:**.**::*** :** * : .. ::.** *** ** :********: * ******** : .. :. :: . : : . : : . : . ** *:.***** :: * * *.*** ::*:****:**: :* :**::*:* *::.:* : : *: ::.: * * :* * ::::*** **:* : *****:..** * . :**: .*: ::***** :*.* .*:::. .**:**. ** :* **.*.*. ****.*.: **::**:**:**:*. :* .**:*: .:: * :: :*.****:*** **: ** *:.* . * * : *: . : : :: : : * . .: **. :..** ****.*.*: ** . * *:**:. .:***. * ** **: .*::**..*: : .: **:.:*. *::**.*:.**:**:*: * *.: *:*:* :... . *:*.***:**:::*:**: ** * ** *******..::: * .**:*****:::: * * ..* : : * .:: :* .* :*: **: ** ** * *:***. . : * :* ***:::::****. : .: **. * ***:*: ***:* * *:**** :* . *: *:.:*:*:*:**: . .: . : ..*******.:*..:***::*:.**: **. :::. *:.: : :::** * *. ****.*:********* :*.**.** *: * : .: : *: :.:: : :**:**:.******:::*:.: **:** ** ::: .*.**: *.******:***..*::.**.:* ::* **** ***:*::*::.. *: ::***** ** :**:** * :*******..:: * *::* **::* *:::** * . ***** ***:::::*: ** :: * **** : :** ** ** *: * : : . . . : * . .: * . *: : .. * . : : . . : : : : : . * * * . : * . . .. : .* : . :**:* .:** . : * : * :.*.*:: :..: : : : :* :* * . * * ** * ** * : : . :** **: :****. ** ***:* * ", "identical_positions": 646, "similar_positions": 587, "identity": "24.1%" }, { "cls_id": "homologset.agr.FB:FBgn0001325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PZK1-1", "uniprot_id": "A0A8M9PZK1_DANRE", "id": "A0A8M9PZK1-1", "name": "", "aln": "MPHSLQQKHAQQMLLLCQGINGTREDGPAPHSWSHKRSYSDLEKMACAADSCIQFTRHASDVLLNLNRLRSRDILTDVTILVNRQQFRAHKTVLMACSGLFYSIFTDSHKCNLNAISLDPKVDPEGFAILLEFMYTSRLALKESLIMAIMNTAIYLQMDHVVDTCHRFIKSSDSSIKLPREDFLVSPLLLPQDIHSYRPHEVMDNVSGRSATFRDGRPYGVCMFNGVNAPNNSYLYGQFPMQGFPFPLCKLTDTKNTFSDFSKGGIIHHKHCSPSDGNNPVLNDFTRSATSGSSAVCHTGSYSSRELGRDEDMKRETLEGVVHSIGMSSRKHGFISLAQEQQRESGKEQSSLAEEHLSHQHYSMGISSNGRKTLMSSPQSPLKSDCQPNSPTESSSSKNAALAQALQPPTSQGTSDPKARNWKKYKFIVLNQSSKEEETNPPDPGMHSPQRPGLSAFLHHVDSEHPDSKVTTKISEQGEDFPAPQASRLNNIINRSLEGSQRNIDSHSSLYMNHLKCSSCGSQSPQHSDVCPNTSASRLAEEMSEMHSEYSDSSCENGTYFCNECDSKFAEEEALKRHTLQVHSDKPYKCDRCQAAFRYKGN-LASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAH-------VLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKIQYRMSSTELPTDLTKAC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIF1-1", "uniprot_id": "A0A8M2BIF1_DANRE", "id": "A0A8M2BIF1-1", "name": "", "aln": "--------------------------------------------MSCAADGCIKFTRHAGDVLFNFNRLRSRNLLTDVTIMVGGQQFRAHKTVLMACSGLFYSMFADNPKSNLSLISLDPKVDPDGFAILLEFMYTSCLTLKDNFIIATLNTATYLQMDHVMETCQRFIDSRGLCMKQTRTEMLVNRGCLSSEAPFIEALNPQSSVNFSTYTSPN-LHYAVSTCT----ENPTRFYRHLPLP------LEPSNPTNPLWQIPKTTVIAHQQHSLPE--------------SGTSARTITN--AAVEDG-DKERNRPS------------------VLFRSARAEGNRKAPLLSSEVENIEACHTGG-----------PESPLRSDCQPNSPAESSGCS----RRPASPPSS--ITYAKVHNWKKYKFIVLN-STDNSSLTPP-----------------HTVSESTNQNAEHK----GQD-------------NRSTDECIKKEEHGSSVHNTFTEESSMGSTN-----------------------------SAERERVYCNECESEAEKPQWLQ-------DGKPYKCDRCQAMFHYKGNPLSSHKSVHTGEKPYRCNVCGAQFNRPANLKTHSRIHSGEKPYKCETCSSRFVQVAHLRAH-------VLIHTGEKPYPCDICGTRFRHLQTLKSHLRIHTGEKPYHCENCDLRFRHKSQLRLHLRQKHGAITNTKVQYGRTRPELTCP-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07247-1", "uniprot_id": "KRUP_DROME", "id": "P07247-1", "name": "Protein krueppel", "aln": "---------------------------------------------------------------MSISMLQDAQTRTLAAALAGIKQEDVHLDRSMSLS---PPMSANTSATSAAAIYPAMGLQQAAAASAFGMLSPTQLLAAN--------------------------RQAAAFMAQLPMSTLANTLFPHNPAALFGAWAAQQSLP----------------------PQGTHLHSPPASP-----------------HSPLSTPLGSGKHPLNS--------------PNSTPQHHEP-------------------------------------AKKARKLSVKKEFQTEISMSVNDMYHTSGG----------PISPPSSGSSPNSTHDGAGGNAGCVGVSKDPSRDKSFTCKICSRSFGYKHVLQNHERTHTGEKPF---------------------ECPECHKRFTR-------------------DHHLKTHMRLHTGEKPYHCSHCDRQFVQVAN----------------------LRRHLRVHTGERPYTCEICDGKFSDSNQLKSHMLVHNGEKPFECERCHMKFRRRHHLMNHKCGIQSPPTPALSPAMSGDYP-VAISAIAIEASTNRFAAMCATYGGSNESVDMEKATPEDDGPLDLSEDGASSVDGHCSNIARRKAQDIRRVFRLPPPQIPHVPSDMPEQTEPE-DLSMHSPRSIGSHEQTDDIDLYDLDDAPASYMGHQQH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:. *:. : * .: :.. :* .* *: * .: ::. . * :: . * : :: .: * : . : . *.. . . ..: : : :: . . . : : . . ..::. :. : . :: . : . * ** *...***. :.:. . . .*. . : . **.:: * . . .* * .: : . :: . : .. : .. . . . . *: *:.: . : *: . **::*:**: *: : : : : ::: .* . ..:: * . :.. . * * .. .* :* * . * .. . .. *: * :: :*: . : *: .. : . : :* :* :. *: :*. : . ", "identical_positions": 48, "similar_positions": 166, "identity": "6.33%" }, { "cls_id": "homologset.agr.FB:FBgn0001330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZ73-1", "uniprot_id": "A0ABK0LZ73_RAT", "id": "A0ABK0LZ73-1", "name": "", "aln": "-------------------MFGQGRRVGGLKRGRRRSTRPASAPGRTAWARRRPAPPCSPAPPRARSPASARSPRGPPPSATLELIVTTLLHTVEPVGLAKALSWSGPVPFKRLKNRRADKDVLKGVDASNALVLPGRKKKKTKAPPPSKKERKPLTKKERKVLQKVLEQKEKKSQRAELLQKLSEVQVSEAEMSLFYTTAKLGTG--DRMYHIKERK--PDQPAAQGQE----------------------------------------------------------------------KVSSLSGAHR------KRHRSSSTEEDSEASEDSEP---EEVTADQPRTSTGADLVHPPPATSEIKSPVPTPQPPPPGTSAPPET--------------------------------------------PASAPPP-ALAKPAVFIPVNRTPEMQEERLKLPILAEEQAIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGYSSEDS-----IIGVTEPRRVAAVAMSQRVAKEMNLSHRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVALRAKRHLP-------LKLLIMSATLRVEDFTQNQRLFTTPPPVIKVESRQFPVTVHFNKRTPLDDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFPIRCSQPQEMEED---SAEGMR------------------RFKKSRTRARKAQA-----MALPQINLDNYSVLPAG-EGDEDREAEMDDEEEALGSDLDLDLGDS-EANEGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVIATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGD-FEQFPPPEITRRPVEDLILQMKALNIEKVINFPFPTPPSVEALIAAEELLIALGALQAPPKQERMKKLQMSQLSCPITALGRTMSTFPVAPRYAKMLALSQQHGCLPYTIAIVAAMTVRELFEELDRPAASEEELAELKGRRTRVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYAGCS---PQFCQANGLRYKAMLEIRRLRGQLTTAVNAVCPEAGLFLDPKMQPPTESQVTYLRQIMAAGLGDHLARRVQSEDLLDP----KWKNAYKTPLLDDPVFIHPSSVLFRELPEFVVYQEIVET-----TKMYMKGVSTVEIQWIPSLLPSYCQFDAPLEEPAPTYCPESGRVLCHRASVFYRVGWPLPAVQVDFPEGIDRYKYFARFLLEGQVFRKLASFKSCLLSSPNTMLKTWARLQPR----TETLLRALVAQKADSRDSLLAAWKKNPKYLLAEYCEWLPKAMHGDVEKNWPPTTDR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY37-1", "uniprot_id": "DHX37_HUMAN", "id": "Q8IY37-1", "name": "Probable ATP-dependent RNA helicase DHX37", "aln": "--------------------------MGKLRRRYNIKGRQQAGPG------------------------PSKGPPEPPP----------------------------------VQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTG--NRMYHTKEK---ADEVVAPGQE----------------------------------------------------------------------KISSLSGAHR------KRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPP--------------------------------------------AAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDS-----IIGVTEPRRVAAVAMSQRVAKEMNLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLP-------LKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMR------------------KFKKSRARAKKARA-----EVLPQINLDHYSVLPAG-EGDEDREAEVDEEEGALDSDLDLDLGDG-GQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGD-FEQFPPPEITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCT---PQFCEANGLRYKAMMEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEMLED----KWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVET-----TKMYMKGVSSVEVQWIPALLPSYCQFDKPLEEPAPTYCPERGRVLCHRASVFYRVGWPLPAIEVDFPEGIDRYKHFARFLLEGQVFRKLASYRSCLLSSPGTMLKTWARLQPR----TESLLRALVAEKADCHEALLAAWKKNPKYLLAEYCEWLPQAMHPDIEKAWPPTTVH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYU1-1", "uniprot_id": "A0AB32TYU1_DANRE", "id": "A0AB32TYU1-1", "name": "RNA helicase", "aln": "MNVSQAADLETLTLLQISVFGCEELAMGRLRKKHNWKGRQQSTSVQ-----------------------TAAADR-QTN----------------------------------VQVEIQDGAVLKGVDDCNALVLPATKTKKQKVERPVTK-KKALTKKQRKNLEKVLEQKDKKAHRAEVLSKLAEVQLPEAELKLLYTTAKLGTG--GKLYHIKESVN-EGQDGGSSSV----------------------------------------------------------------------KISSLSGANR------KRRREADEEEEENESEMSESSEDDDDSEESDSSEEEKEKISEEKHTEEQQQQQVLKEETKPKEADMKEE--------------------------------------------KKAETWTKEDCKPAVFIPVERLPEIQEARLRLPVLAEEQIIMEAVKDHECVVLCGETGSGKTTQVPQFLYEAGFASSGG-----IIGVTEPRRVAAISMSHRVATEMNLSSGVVSYQIRYEGNVTENTKIKVMTDGVLLKEIQRDFLLQKYSVIIIDEAHERSVYTDILIGLLSRIVPLRNKKGLP-------MKLIIMSATLRVEDFTENKRLFSSPPPVIKVEARQFAVTVHFNKRTPMDDYTGETFRKICKIHRMLPPGGILVFLTGQAEVHSVCRRLRKAFP---YKPNREHTDMMETEEDLK------------------KSKR-----AKKKN-----VSLPRINLDNYSALPVD-EGDEDRQAGID-EDDGEGSDLELELGDHPDTDHEEKADPSIPLYVLPLYSLLAPEQQAKVFRPPPAGSRLCVVATNVAETSLTIPGIKYVVDCGRVKKRFYDRVTGVSSFKVTWISQASANQRAGRAGRTEPGHCYRLYSSAVFGD-FSLFSEAEITRRPVEDLVLQMKDLNIEKVVNFPFPTPPSSEALIAAEELLISLGALEKPARHGRLSEMEKARLSCPISPLGRAMAAFPVAPRYAKMLALGRQQGCMQYIITIVSAMTVREIFEDYDRPAGSEEENVKMSGKKARSVQMRRLWAGQGASLLLGDLMVLLGAVGACEFAGLT---PQFCEENGLRFKAMLEIRRLRGQLTNAVNAVCADADVYVDNKMAPPTEAQVLCLRQIVLAGLGDHIARRVQAEELLDP----KWRNAYKTPLLDDPVFIHPSSALHKTLPEFVVYQEIMET-----TKMYMRGVCAVQDDWIPKLLPQYCHFSAPEESPAPRFCPLIGRVKCHQQSTFFRVSWKLPAIEMDYPEGLERYKLFAKFFLEGQVCPKIQKFSSCLLSSPSTMLKTWAKLQPR----TEVLLTALVSEKADNRTSLEAAWRKNEKYLLSAYCQWIPESLHEEVSKIWPPIGQADPR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46072-1", "uniprot_id": "KZ_DROME", "id": "O46072-1", "name": "Probable ATP-dependent RNA helicase kurz", "aln": "--------------------------MG--KKVHNAKARQNPQTIVD----------------------NSAVKKIQID------------------------------------VDAVAGGNQVGYDEANALVLPSEK-RATKIKVDKVQHVKILSKKQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLA----------------------------------------------------------------------EKSSASGLRVNAIKGSKRKLLVEEEEELQAKRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPPIKK--------------------------------------------LKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHK------MIGVTEPRRVAAIAMSKRVAHEMNLPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQP-------LKLIIMSATLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTP-DDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLE--DESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALE-------VAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETG--VQRDEDVAPGAN---RFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLCNIREVREDPAPRFDKTSGKIFCHVDATFGKSGWELPLGEVEMPLSEKACCYFGMFLLDGEVCSRLADFRSKLKSTPASVIKSWSSMNNK----VLRFKRALITKQIHNRQALIDQWNSDPHFLLEEYQNLLYDVALSELTPLWPPVDKKEPQRQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04217-1", "uniprot_id": "DHR1_YEAST", "id": "Q04217-1", "name": "Probable ATP-dependent RNA helicase DHR1", "aln": "--------------------------MGTYRKRFNEKARSGHMAKLKELKRIRN---------KQFTRQDENDERVENPDS--------------------------------APAESSTTEPNANAEILEPLTEEEKKMKKRKLQELFTPKESKVSRLKKKRLDKFIEHQLKREERKTIIGKLQDYKIDTS---LLTSSKRLGEGRQTKKEEFKEALSLERQGRGNEQTNEILYEEYEPKVWDEYGEGGSSEDDDGEDDFEASFGSMPKPTDNEEKKSSGFIDHRPAKFGGSGLSFGFSNIKVINKESKTPKKKYNWRQRVEMEELKKHGKEDEMDFDTTSEDDDEEEDQEEEDKMHPSENPLEEVESADSETGSEKFDQNDVANEFKDWANQEIKKLEGRDQELVTPTLNIDYKPIIRKEDLDDGLQEAYVPINENSTRKAFYVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQPRRVAAVSMAERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLTKYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENKTLFPIAPPVLQVDARQFPVSIHFNRRTA-FNYTDEAFRKTCKIHQKLPPGAILVFLTGQQEITHMVKRLRKEFPFKKNSKYNKDLETPVSKMGIN---------------------------SKTTD-------LEAEDIDFSVQVIDQDKFKSAIRYEEDEGNSGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLYSLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKERKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFEQFSKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQYLGALDN---------------KEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRKPNPDENLDDKIREHDESTPGMDPELKKELRSKFYKSRSQFSKLD---------KFSDVFRLLSVVSAMDYVPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNEDLKSD----------------------IPSVIQIKLLKQMICAGFVDH-------VAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLGEMPPKYMLYYSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNLSPTERYCYVVPRFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITRKGFQTITGEEKEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: . . * . . : :.*. * : * . ::: ::* *: .:::: *: * :: .* : : :: : .* : . : . . : : . ** : . . :. : . : :.:: * * *:*: *::**::.**: :**:: .: *::.**********:********:. ::*:*:******::*:.*** *:. *.* **::.... *::*.*******:*: ** * :*. :*:******.: ****:*:*** * ** * :**:********.**::* ** .**:::*::***.*::**::**. :* * :** ***. ** *.**:*:*** *: : ::**: ** : : . * * ::* : . . * : . .* : : ** ********..::* ::* * * ***:::*********** ::****.*: * * *:. .**.:* * : *:***:**:***** .***********: . *. *. .:* : ***.::***: : :..:::****:**. * * . * ****: :: *: :: **::**:.*** :. :: : * : :*::::* : : : : . . .: : * * . : . .::: : : .: :.. : . . . : .. : : * :.:* : :: . .*.: : :: : : ::. . : . :: .: : * : : . . * : . * . . : . . : : :: . .: * * : : : : . ", "identical_positions": 250, "similar_positions": 290, "identity": "17.54%" }, { "cls_id": "homologset.agr.FB:FBgn0001341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35821-1", "uniprot_id": "MBB1A_RAT", "id": "O35821-1", "name": "Myb-binding protein 1A", "aln": "MAEMKSPTKAEPASPAEAPQG-----DRRSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRTRPS----DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIQ-----------------LCDILGQIQEKYNLQAMNKAMMRPTLFANLFGVLALFQS--------------GRLVKDKEALMKCVRLLKILSHHYNHLQGQPVKALVDILSEVPESMFQEILPKVLKGDMKVILSSPKY-LELFLLARQRVP-----AELESLVGSVDLFSEDNIPSLVNILKVAANSVKKEQKLPDVALNLLRLALQENK-----FERFWKEVLEEGLLKKPSYTSSYMCFRLLGASLPLLSDEQ-LQLVMRGDLIRHFGEHMVVSKSQNP--LRFIPEISAYVGTFLEGCQDDPKRQFTVMVAFTAITNQGLPVMPTFWRVTRFLNTEALQNYVTWLRDMFLQPDLDSLVDFSTANQKRVQVASLNVPERTVFRLRKWIIHRLVSLVDHLHLEKDEAV--VEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLEDGNRGVIVSAFFSLLQTLS-------------VKFRQTPDLAENGKPWTYRLVQLADMLLKHNR-NVANVTPLTAQQRQAWDQMMSTLKELEAQSSETR---AIAFQHLLLLVGLHLFKSPAESCDVLGDIQTCIKKSMEQNLRRSRSRAKASQEPVWVEVMVEILLSLLAQPSNLMRQVVRSVFGHVCSHLTPRGLQLILAVLNPETNEDEEDNVVVT-DTDEKQLKHGEDADSDSEDSKNSE------SDVDSEDGEESEE-------EDRD------KDVDPGFRQQLMEVLQAGNALG-GEE-EEEEELGDEAMMALDQNLASLFAEQKMRIQARHEEKNKLQKEKQLRRDFQIRALDLIEVLVTKQPEHPLILELLEPLLNIIQRSMRSRGSTKQEQDLLHKTARIFMH--HLCRARHYCHEVEPGAEALHAQVERLVQQAGNQADASVALYYFNASLYLLRVLKGNTTK-RYQDGQKLEGADIKSEPKDSEVQTTSCLDLDFVTRVYSASLESLLTKRNSPLTIPMFLDLFSRYPVICKNLLPIVVQHVAGSSRPRHQAQACLLLQKALSARELRVCFEDPEWE-QLISQVLGKTTQTLQTLGEAQSKGEHQRELSILELLNTVFRIVNHEKLSVDLTAFLGMLQGKQQKLQQNLQQGNHSSGSSRLYDLYWQAMNLLGVQRPKSEKKNVKDIPSDSQSPISTKRKKKGFLPETKKRKKLKSEGTTSEKKAASQQDAVTEGAMPAATGKDQPPSTGKKRRKRVKANTPSQVNGVTVAKSPAPNNPTLSPSTPPAKTPKVQKKKEKLSQVNGSTPVSPVEPESKK-HQKALSTKEVKRRS--SQSALPKKRARLSLVSRSPSLLQSGIRKRRVARRRVQTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPV4-1", "uniprot_id": "MBB1A_MOUSE", "id": "Q7TPV4-1", "name": "Myb-binding protein 1A", "aln": "MAEMKSPTKAEPATPAEAAQS-----DRHSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRTRPN----DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIP-----------------LCDILDQIQEKYSLQAMNKAMMRPSLFANLFGVLALFQS--------------GRLVKDKEALMKSVQLLKILSQHPNHLQGQPIKALVDILSEVPESMFQEILPKVLKGNMKVILRSPKY-LELFLLAKQRVP-----TKLESLMGSVDLFSEDNIPSLVNILKVAANSVKKEHKLPNVALDLLRLALKESR-----FELFWKKVLEEGLLKNPSWTSSYMCFRLLGASLPLLSEEQ-LQLVMRGDLIRHFGENMVISKPQNL--FKIIPEISTYVGTFLEGCQDDPKRQLTMMVAFTTITNQGLPVMPTFWRVTRFLNAEALQSYVAWLRDMFLQPDLNSLVDFSTANQKRAQDASLNVPERAVFRLRKWIIHRLVSLVDHLHLEKDEAV--VEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDRNRGVFVSAFFSLLQTLS-------------VKFRQTPDLAENGKPWTYRLVQLADMLLNHNR-NVTSVTSLTTQQRQAWDQMMSTLKELEARSSETR---AIAFQHLLLLVGLHIFKSPAESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPVWVEVMVEILLSLLAQPSNLMRQVVRSVFGHICPHLTPRCLQLILAVLSPVTNEDEDDNVVVTDDADEKQLQHGEDEDSDNEDNKNSE------SDMDSEDGEESEE-------EDRD------KDVDPGFRQQLMEVLKAGNALG-GVDNEEEEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRRDFQIRALDLIEVLVTKQPEHPLILELLEPLLNVIQHSMRSKGSTKQEQDLLHKTARIFMH--HLCRARRYCHEVGPCAEALHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTNK-RHQDGHKLHGADTE----DSEDQAANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRYPVICKNLLPVLAQHVAGPSRPRHQAQACLMLQKTLSARELRVCFEDPEWE-QLITQLLGKATQTLQTLGEAQSKGEHQKELSILELLNTLLRTVNHEKLSVDLTAPLGVLQSKQQKLQQSLQQGNHSSGSNRLYDLYWQAMRMLGVQRPKSEKKNAKDIPSDTQSPVSTKRKKKGFLPETKKRKKLKSEGTTPEKNAASQQDAVTEGAMPAATGKDQPPSTGKKKRKRVKASTPSQVNGITGAKSPAPSNPTLSPSTP-AKTPKLQKKKEKLSQVNGATPVSPIEPESKKHHQEALSTKEVIRKSPHPQSALPKKRARLSLVSRSPSLLQSGVKKRRVASRRVQTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQG0-1", "uniprot_id": "MBB1A_HUMAN", "id": "Q9BQG0-1", "name": "Myb-binding protein 1A", "aln": "---MESRDPAQPMSPGEATQSGARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRGRPK----GSEMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLP-----------------LCSILQQIQEKYDLHQVKKAMLRPALFANLFGVLALFQS--------------GRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALVDILSEVSKATLQEILPEVLKADLNIILSSPEQ-LELFLLAQQKVP-----SKLKKLVGSVNLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDK-----FPRFWKEVVEQGLLKMQFWPASYLCFRLLGAALPLLTKEQ-LHLVMQGDVIRHYGEHVCTAKLPKQ--FKFAPEMDDYVGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLSPPALQGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSLHMPERAVFRLRKWIIFRLVSIVDSLHLEMEEAL--TEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSSAFFSLLQTLS-------------TQFKQAPGQTQGGQPWTYHLVQFADLLLNHSH-NVTTVTPFTAQQRQAWDRMLQTLKELEAHSAEAR---AAAFQHLLLLVGIHLLKSPAESCDLLGDIQTCIRKSLGEKPRRSRTKTIDPQEPPWVEVLVEILLALLAQPSHLMRQVARSVFGHICSHLTPRALQLILDVLNPETSEDENDRVVVTDDSDERRLKGAEDKSEEGEDNRSSE------SEEESE-GEESEE-------EERD------GDVDQGFREQLMTVLQAGKALG-GEDSENEEELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRRDFQIRVLDLVEVLVTKQPENALVLELLEPLLSIIRRSLRS-SSSKQEQDLLHKTARIFTH--HLCRARRYCHDLGERAGALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEGCVHETQEKQKAGTDPSHMPTGPQAASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRHPVLCQSLLPILVQHITGPVRPRH--QACLLLQKTLSMREVRSCFEDPEWK-QLMGQVLAKVTENLRVLGEAQTKAQHQQALSSLELLNVLFRTCKHEKLTLDLTVLLGVLQGQQ----QSLQQGAHSTGSSRLHDLYWQAMKTLGVQRPKLEKKDAKEIPSATQSPISKKRKKKGFLPETKKRKKRKSEDGTP-----------AEDGTPAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPSTP-AKSPKLQKKNQKPSQVNG-APGSPTEPAGQKQHQKALPKKGVLGKS--PLSALARKKARLSLVIRSPSLLQSGAKKKAQVRKAGKP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRL5-1", "uniprot_id": "MBB1A_DANRE", "id": "Q6DRL5-1", "name": "Myb-binding protein 1A-like protein", "aln": "MVAVMQTDMGETENSAVRPKVT----DAKGILKQNRQFLDYFWDIAKPDRQIRLKAIEDLINYLKNSEQ----ADELKYTLKRLVDGLSHTREDARSGYSVALAQLLSVFEEIS-----------------LKSTLNSVKEKHNLLTASKKLIRNAVFGNFFGVLALSQS--------------TRLHKEPQVMLECVQLLQSLSEYREHLRDLPRKTMVDILSETSQDVFEEVLFSALQSDLTSALKSPEQ-LELLLVALQKFPSVLKPKKLKKLLGTTAVITKQNMPRLVEVLKTAARSVKKENILPAVALDLLQVSLREDN-----FEMFWTDAIITGMMSEMPGPTHYLSFRLLGASLPLLSIPQ-LQFVLSGDVMRQYGEHTMSAQMPDR--FKFAPEMAGYVGEFMQSCTD-PDKQLVVVLGFTQLTNQGNPVVPSYWKALENMHPSAVQRYVDWLIEAFCKPQLENCLDFSTRRQKGNQEAAVES-ESCVSRFRKWIIPRLTFIVENQQIKKQEAL--VMKVVRFIFFHAFFEVKKPTSEIPETTQALSVPINQQTRTAVVSGFYSLLQALNSMMVLGESVEVQGLNFRRIVGVQADGSMWIYSVFQFASMLLNQNK-YVKSLQSFSPEQRQGWDSVLESVEALRKKAKTASSPEHTAFQQLFLLIGIQMFTSPEESLDLLKDLQTCMEKAQAKKSK----KKKATDEPHWVEVIVEILLSLVSQPSRLVRSVCKTVFGRICPHLTQAALSSILNVLDPNKDEDESG-VVVTDDKKRKLKEEDEDDDDEEEDDDNDEGDDDDDDDDEEEGGEEGEESSDSSDDEEEDEAMEEGQEVDQNFRLELMKVLQGQNALATEEDGSDDEELDDAAMMKLDGSLASLFLEQRKKIQAKKDEKDRLNKEKGLVRDFKIKVLDMVEVFLSKQGFSPLVLGMVEPLLSVIENGMSS-ESSQPEQDYLRRVADIFRN--RLCRGKFYCKEIDGREAELHEMLERLIGRAQKLTDSSVALYYFSAALYVLKVLRGSVVD--------------------QELSTMGKVEVERATTCLKNALTSFMTKRKSPLTGAMFIDLFHRFPVLCVNLMDTALENITAGLRDHQQGQACFIMLKALQCKHVKNLMTGEQTT-ELYKKVVDQLTKSLENV-QCKNKTAHDKVVKALELCLHVVKIVLNQKMRVNLELLQDVL--------ASMNAEGCLEKTGKLEDTYWSVMRLFGVIKPKMEK--VKKVPEAEQTEETTK-KKKGFLPETKKRKNRKKPTILEG----------KETETPVEKTPEGASGEGKKNKNKKKNKKRKQQAGEETQDQPTPKKAKMQ-----QQQQQKQKKKKKKKGADGE--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39985-1", "uniprot_id": "DPO5_YEAST", "id": "P39985-1", "name": "rRNA processing protein POL5", "aln": "--------------------------------MTGKVNRDLFFKLASDLREERLHAAVALIKDLSALDLPD-DAEEWSYVLNRLIKGLSSDRNSARLGFSLCLTEVINLAVNMPPGQRPKGLESTNEFLSTLSTILNVNVNEGTKKSMKGKDERGILFGKLFGLKSLLNEPLFSEIFV-----KDLEKGNTEFFIRFTEQLIDLALKKNWIKEPCFFTLFQTMKMLLPFMDESSAEKILLIYDKYDLTLTNEGLSTYLLLKYEGDE----SLIPSVLDLKNPGWKDNDPLARGNLPLLTKVLRNSSVIPDANGGLKETKKQKNTNWNPRLHFVWSVLLPLFGNGKLENTSHISKKRKKTNNKKVQNSIQ-FPEFWKMAVDESFFNEKASSERKYLGFLIIDAAFKAVPGSYIGFCFSQNVMRTLINQSIDSQRVLNKISQLTLDSIVKACEEDSANRLVPCLNAMLFGPHGS--INFDKLTKSGTVSKLIAIKELPSTVLAQLLDVFFLQLQDKKGVLSHTLF--ALDSILHIVRAHKVEINDMDIMKPVLRPIVYMAFFKHTSDDLKLEQLHELAKER----------LYSILGELTINKEIRCKDPEINSWQYLTLKLILDI-ENSHVGDLINPLDENLENIKNEAISCLSKVCRSRTAQSWGLSTLLSMCLVQLYAGDTDSISVIEELCEFSKHENNSMVG-----------------ITEILLSLLAQKKALLRKLSLIIWQQFIEEVGLEELQILLDILKARENKQGFAQLFEGEEEFEEIKEENDASEDESKTGSESE------SESESDSDDADEK------------------DEEDEANEDILNIDKEATSALVKALNLPDNIVNDKGEVDLDQ------------LEGLSDDGGDDEDEESMDDEKMMELDDQLSEIFKRR----------KEALSSISTGNQRKFEVKQSRENVISFKHRVVD--MLAVYVKYCEKLT---------LANKSEHSNNLGGSLSKLVYF--IIPMLKCVN------------------------------------ETLDRPLADKISKLLKGKIFKIKVTAFKDMNKDIELMDLLKKTHKLMLTSKP----GQHAAVFYSMCSTSSLFLSKLYVEIGGN-DKLDELIDLYTATTKEWMQKGKCG-PNIFIDFINWLSSKKQTVMDKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W5E4-1", "uniprot_id": "MBB1A_DROME", "id": "Q9W5E4-1", "name": "Myb-binding protein 1A", "aln": "--MKSKVDKPVTNGAPNATKTKAKEDRKRAKTQKSEADSQIPAKILKKSKKEKPAETEEKENTASNANLKVSQINKAVFVVFKKMQGSQLTKKMINSLITLLRDDTNAEQRTAT-----------------TGYVLKRLIRSTGADDMKTVSLAASYIHCILNAVPAIDAFEVLETLKRDLAVGSQQRGKEDSLAAVGQLVTAFCILQTPQFAKAEPKLVTAVFQILAAQLKG--REYLVSLCGDILAVSFKQLPAAIFEEYVWP------LLQPELNKPLSGLKVNTCDVLLAVHLTFSSVLGRENILASLWPKKPVYTQLFD-----LYFSGSTIHSDGVYARLASFLVNGGKDMLAAWQQYIDSKQPLKLNAAKACAIQVLSHVLLNFKPREEQLILDIFTPTCVQFLLHECSS---VKWDKGEGKKPSLKKLKEICFKFEGSLVLCYEKQFQNDDNKLHLLLKLLEHTLQLDSVISLPRFCQKLINQLSVESLHKLYDYYNNKLYSLEDEDRVSRVHCLNQMQLILNHSKLSQTAKWRQKQLNYLLLAGLFHLDASKKPCEAAQASAFSRQCAAR-----------CEEIFLGSLLHKCSGLPGLCQLLQKTLSYLNKELGQPDAESKLRSPRDESLQKAWKQVEKLLERPSKESDVVGQSFEALILFVSLALCTKIPPSITVLEDLIICRKNALQKSKE------QVNEELKWQDVLTDALLQLLLQTGHFWREFVQLVATALIPHLEHGNLEQVLEVLN--MNKNPLSKKSDGEEESDDELDKEESLKDSSDDSEDED------EDEEEDEGEDDAES--------------HLAQIRESVRQALVNDGDADDDGASSVDWNDVDEEQGERLNAALERSFQMFRPKSRKAQEKERPTKSERIDSTNLLHFRIRALDLLELFITKKPTQSVILDVLHCVFQVYSHCAADSKLQSLREASLKLLKKILARNIELKENQSTAPILEAIEQLMSSGEEHSEEDQENGKQPASRQAKRDIIIWRDRCFAYLVSQ----------------------ASADGEPKKSAVWPLLVEFLELWVAKRRSRLSLASFEALFQSGQWQGVAPLAVVLASHLDVQKTRSFRRAQILKLLSEQGRRLEVAFKDNNSSSKKFEKQIARYVN--QLETKASSSKELNLLLKILAQGGEKWQKLREQIQLVAKDLQ-----------------------------------------------------PNKKVAKQKKQAAAKPMVVEDEEST------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : .: . :: : : .: :.: : : * :: . :: : * .. . : ::. . : . : : . : :. :. : : . * * . * :. : :. . * : : : : : . * : .. : : : * . : . . : * : . :: : . : : : : . . .. . . . * * . : : : . : .:. *: : : : * :: :: .: . :.: ** *: * : *.. : . .: *. :* :*. .:: : . : ... . . ..: .: :.: .: . : : . :: . : . : . :. . :. * :. :..:: . :. . . : . * . : . . : : . . : : : :. . * : * : : . : . : : . . : . : :. : : .: ", "identical_positions": 25, "similar_positions": 204, "identity": "1.73%" }, { "cls_id": "homologset.agr.FB:FBgn0001491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41223-1", "uniprot_id": "BUD31_HUMAN", "id": "P41223-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGH1-1", "uniprot_id": "BUD31_MOUSE", "id": "Q6PGH1-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70454-1", "uniprot_id": "BUD31_RAT", "id": "O70454-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q567Z7-1", "uniprot_id": "BUD31_DANRE", "id": "Q567Z7-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KPPPDGWELVEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRLHHQRSRYIFDLFYKRKAISRELYKYCIRGGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKGKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97454-1", "uniprot_id": "O97454_DROME", "id": "O97454-1", "name": "Protein BUD31 homolog", "aln": "MPKVRRSR-KPPPDGWELIEPTLEELEQKMREAETEPHE--GKRITESLWPIFKIHHQKTRYIYDLFYRRKAISRELYDYCLKEKIADGNLIAKWKKSGYENLCCLRCIQTRDTNFGTNCICRVPKCKLEEGR--------IVECVHCGCRGCSG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25337-1", "uniprot_id": "BUD31_YEAST", "id": "P25337-1", "name": "Pre-mRNA-splicing factor BUD31", "aln": "MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::: * *..***:* ::*** ::: ::*:*:.: . . : *.** *:::***::***: *:*:*****::**.: :: ** *****:* ***:********..:** *:.******: :** : :*.*******:. ", "identical_positions": 70, "similar_positions": 49, "identity": "44.59%" }, { "cls_id": "homologset.agr.FB:FBgn0001565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0E0-1", "uniprot_id": "A0A0G2K0E0_RAT", "id": "A0A0G2K0E0-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "--MEDQ--------EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQLLLHKKATGPVMEQA-VRGLVLVPTKELARQAQSMIQQLASYCARDVRVANVS-AAEDSASQRAVLMEKPDVVVGTPSRILNHLQQKN-LKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLP--RIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATD-----------------------AEILGPQVKAKRQGRGSKGDKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPTEQS--------SLGKIEELLSG----EGQAP--ILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGNVPDYLVPAALRGLVHPR-------KKRRKMPFS-RKAKKVKTQNPLRDFKHRGKKPKPTAKPS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0R4-1", "uniprot_id": "DDX56_MOUSE", "id": "Q9D0R4-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "--MEDQ--------EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQSLLHKKATGPVMEQA-VRGLVLVPTKELARQAQAMIQQLAAYCARDVRVANVS-AAEDSASQRAVLMEKPDVVVGTPSRVLSHLQQNT-LKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLP--RIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATD-----------------------AEILGPQVKGKRRGRGSKGNKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPAEQP--------FLGKIEDLLSG----EGEAP--ILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPAALRGLVHPR-------KKRRKVPFS-RKAKKVKAQNPLRDFKHRGKKPKPAAKPS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY93-1", "uniprot_id": "DDX56_HUMAN", "id": "Q9NY93-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "--MEDS--------EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQLLLHRKATGPVVEQA-VRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVS-AAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDS-LKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLP--RIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDCVIATD-----------------------AEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQF--------HLGKIEELLSG----ENRGP--ILLPYQFRMEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPPALRGLVRPH-------KKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKFRPTAKPS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRI0-1", "uniprot_id": "Q9VRI0_DROME", "id": "Q9VRI0-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "MSQMTQ--------KTVQFHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGK-DVVVRARTGSGKTATYALPLIQKILNSKLN--ASEQY-VSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALSESPDIVVATPANLLAYAEAGS-VVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLP--PIYQAVLVSATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQRILAE-ENDKPAILYALLKLRLIRGKSIIFVNSIDRCYKVRLFLEQFGIRACVLNSELPANIRIHTISQFNKGTYDIIIASD-----------------------EHHMEKP--GGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKESK--------VNDSVEKKLCDSFAAQEGEQ--IIKNYQFKMEEVESFRYRAQDCWRAATRVAVHDTRIREIKIEILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQSHLSDMPEYIVPKALKRVVGTSSSPVGASEAKQPRQSAAKAAFERQVNDPLMASQVDFGKRRPAHRRKKKAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06218-1", "uniprot_id": "DBP9_YEAST", "id": "Q06218-1", "name": "ATP-dependent RNA helicase DBP9", "aln": "MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQSHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVPTRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLS-TLLMDQPEIIVGTPGKLLDLLQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDDIQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKTLIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTEYIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNVACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERILSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLASEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARG------------NGTKVKFVPFHNAKKRHSHKKGRVSKPKNGKVDPLKNFK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *. : ** *:*:*: ::*:. *****. **** *: * *::.:* ****** :* :*::: :*. * . *: . .::*.**:**.:* ::::*. *.: :*. ::: .*:. . * :.*:::*.**..:* : . :: *****.**::::*::.::: : :** *:.*:***:.:*: :* ..*. **::: :: :: : * ** : *.::** **:**:::***.::* *:::*.:***.* :*:**.*** . * * :.***:. *: :**:* : . * * * ..:**:**: * *:***:* :*:**.*****..: * .::** :. . :. : . : : *:* :::*.**** .* *:.*: *::::*::*:* *:* .**** .**:* ::** **** *:. *: ** :*:*::* : : : : . : * . : :. : * * . . ", "identical_positions": 165, "similar_positions": 193, "identity": "27.0%" }, { "cls_id": "homologset.agr.FB:FBgn0001612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUU7-1", "uniprot_id": "A0A0G2JUU7_RAT", "id": "A0A0G2JUU7-1", "name": "", "aln": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQFAVRVIGSNFAPTVERDEFL-VAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLNLSEDPRKQASKVTSYASLFAQALPRDAHSTPYYCARPQTLPLNYQDRSTQS---SGSLGSSGISSIGMCGLSGPTPV-QPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPS-QTPTSKAFPNALSRNLTRSRREGDPGGTSEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKAN--LSKSLRDTAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-----------VGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK---TDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNRKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDS-----PEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTREC---MSHYLRVFNFLWRAKRMEYIL-TDIRKG-----HMCNAKLLRNMP-EFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLDTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDTMYRAALEELQRRLQFEEKKKQRETEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGSRGRRSSHT----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58854-1", "uniprot_id": "GCP3_MOUSE", "id": "P58854-1", "name": "Gamma-tubulin complex component 3", "aln": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQFAVRVIGSNFAPTVERDEFL-VAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLNLSEDPRKQASKVTSYASLFAQALPRDAHSTPYYYARPQTLPLNYQDRSTQAQ-SSGSLGSSGISSIGMCGLSGPTPV-QPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPSSQTPTSKGFPNALSRNLTRSRREGDPGGTLEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAKAN--LNKSLRDTAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVN-----------LGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK---TDRLWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDS-----PEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTREC---MSHYLRVFNFLWRAKRMEYIL-TDIRKG-----HMCNAKLLRNMP-EFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLNTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDVMYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLDFNEHYKAREPRLRVSLGSRGRRSSHT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CW5-1", "uniprot_id": "GCP3_HUMAN", "id": "Q96CW5-1", "name": "Gamma-tubulin complex component 3", "aln": "MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFL-VAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSLLPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTGGTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKAN--LSRSLRDTAVRLSELGWLHNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVN-----------LGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK---TDRLWHDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDS-----PEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTREC---MSHYLRVFNFLWRAKRMEYIL-TDIRKG-----HMCNAKLLRNMP-EFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYP8-1", "uniprot_id": "GCP3_DROME", "id": "Q9XYP8-1", "name": "Gamma-tubulin complex component 3", "aln": "----------MSQDRIAGIDVATNSTDISNIINEMIICIKGKQMPEVHEKAMD-HLSKMIAANSRVIRDSNMLTERECVQKIMKLLSARNKKEEGKTVSDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAVASEDPRTQCDNLTQILVSRLNSISSSIASLNEMG--------VVNGNGVGAAAVTGAAAVTGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQGKYLKKDVVTGRFKLDQQNIKFLTTGQAGMLLRLSELGYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKLLAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDNGNDMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVG---VDRLWHDKFRLRLPMLPKFVPMDMANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIFSYT-PDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLDSALRCTNAQYDD-----PDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAMLEST----MPTYKVLFKPLWRMKHMEFVLSMKIWKE-----QMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVS-NKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSLNSSDDPNLQLFGTRLDFNEYYKKRDTNLSKPLTFEHMRMSNVFAVNSRFVICTPSTQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53540-1", "uniprot_id": "SPC98_YEAST", "id": "P53540-1", "name": "Spindle pole body component SPC98", "aln": "-------------------------MELEPTLFGIIEALAPQLLSQSHLQTFVSDVVNLLRSSTKSATQLGPLIDFYKLQSLDSPETTIMWHKIEKFLDALFG-------------------IQNTDDMVKYLSVFQSLLPSNYRAKIVQKS-----------SGLNMENLAN------------HEHLLSPVRAPSIYTEASFENMDRFSERRSMVSSPNRYVPSSTYSSVTLRQLSNPYYVNTIPEEDILKYVSYTLLATTSALFPFDHEQIQIPSK------IPNFESGLLHLIFEAGLLYQSLG-YKVEKFRMLNISPMKKALIIEISEELQNYTAFVNNLVS------------------------SGTVVSLKSLYREIYENIIRLRIYCRFTEHLEELSGDTFLIELNIFKSHGDLTIRKIATNLFNSMISLYYEYLMNWLTKGLLRATYGEFFIAENTDTNGTDDDFIYHIPIEFNQERVPAFIPKELAYKIFMIGKSYIFLEKYCKEVQWTNEFSKKYHVLYQSN----SYRGISTNFFEIINDQYSEIVNHTNQILNQKFHYRDVVFALKNILLMGKSDFMDALIEKANDILATPSDSLPNYKLTRVLQEAVQLSSLRHLMNSPRNSSVINGLDARVLDLGHGSVGWDVFTLDYILYPPLSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKEMLKSNDIIRSFKKIRGYNPLIRDIINKLSRISILRTQFQQFNSKMESYYLNCIIEENFKEMTRKLQRTENKSQNQFDLIRLNNGTIELNGILTPKAEVLTKSSSSKPQKHAIEKTLNIDELESVHNTFLTNILSHKLFATNTSEISVGDYSGQPYPTSLVLLLNSVYEFVKVYCNLNDIGYEIFIKMNLNDHEASNGLLGKFNTNLKEIVSQYKNFKDRLYIFRADLKNDGDEELFLLSKSLR-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : : : . . . : :: : : . :.: . . : : . . . . . : : : *.: . . . : . : . :. .. :: * : . . : . . : . : * * :: : : :. : ::: : :** :: : * . ::* * . *:: :.: : .*. : : : . *: :..:. .::. : : .*: .* : : ***: . . * ::* :. :* *:. : : *::: *** **.: *.: .: : .. : .. : :: * : :: ::: . : : .::. **:*:.**: *:: : * *. : .** :*: *:: :. :. ..::. **. : *. **::::*:* : *:: :: * :*: *** *: ::. .: * : : : . : :: : :: ::: :* :*: * ::* .: *: .::*:: .. : : : . : . : ::: . ...: :.. : . . : . .: *: :. * :*.. :: :: . ** . .* .. ", "identical_positions": 68, "similar_positions": 257, "identity": "7.12%" }, { "cls_id": "homologset.agr.FB:FBgn0001624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62936-1", "uniprot_id": "DLG3_RAT", "id": "Q62936-1", "name": "Disks large homolog 3", "aln": "-------MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPSGGNGASSGYGGYSSQ------------------------------------TLPSQAGATPTPRTKAKLIPTGRDVG-PVPPKPVPGKNTPKLN-GSGP--SWWPECTCTNRD--------------------------WYEQASPAP-------------LLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQP-------------------PPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNN----TNLQDVRHEEAVASLKNTSDMVYLKVAK-PGSLHLNDMYAPPDYAS------TFTALADNHISHNSSLGYLGAVESKVTYPAPPQVPPTRYS---------PIPRHMLAEEDFT---------------------------------------------------------------------------REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKG----------------------------VTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVP--------HTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAER-GKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70175-1", "uniprot_id": "DLG3_MOUSE", "id": "P70175-1", "name": "Disks large homolog 3", "aln": "-------MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPSGGNGASSGYGGYSSQ------------------------------------TLPSQAGATPTPRTKAKLIPTGRDVG-PVPPKPVPGKSTPKLN-GSGP--GWWPECTCTNRD--------------------------WYEQASPAP-------------LLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQP-------------------PPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNN----TNLQDVRHEEAVASLKNTSDMVYLKVAK-PGSIHLNDMYAPPDYAS------TFTALADNHISHNSSLGYLGAVESKVTYPAPPQVPPTRYS---------PIPRHMLAEEDFT---------------------------------------------------------------------------REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKG----------------------------VTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVP--------HTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAER-GKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92796-1", "uniprot_id": "DLG3_HUMAN", "id": "Q92796-1", "name": "Disks large homolog 3", "aln": "-------MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQ------------------------------------TLPSQAGATPTPRTKAKLIPTGRDVG-PVPPKPVPGKSTPKLN-GSGP--SWWPECTCTNRD--------------------------WYEQ-------------------------------VNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQP-------------------PPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNN----TNLQDVRHEEAVASLKNTSDMVYLKVAK-PGSLHLNDMYAPPDYAS------TFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYS---------PIPRHMLAEEDFT---------------------------------------------------------------------------REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLK------------------------------------------GQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVP--------HTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAER-GKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QGS1-1", "uniprot_id": "A0A8M9QGS1_DANRE", "id": "A0A8M9QGS1-1", "name": "", "aln": "-------MHKHHHCCKCPECYEVTRMAALRRMDAPAYGEWQ-PEPYGYPAGYGGGQTLPPQTSG------------------------------------GGGGMGGGGTLGRSKGKMMSAGGPGG-PNPKSQSKGGPKVNGN-NSGGQGGWWPECTCSNRD--------------------------WYDQANPPP-------------IIVNADSLDAGPYVNGSDGMYKYEEIILERGNSGLGFSIAGGMDNPHIPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNDVDVSEVVHSKAVEALKEAGPVVRLLVRRRQA-------------------PPETILEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQTGDRLLAVNN----IILQDVRHEEAVAALKNTSDMVYLKVAK-PGPVHLNDMYAPPDYSSSLGLPPAFPTMVDNHVGHNSSMAYMGGMEPKPVY-QPPQVTPSRYS---------PVPRHMLGEEDFTRAEPIYSAIHKPHGDTSPPS--------------------------PHLCSRGSGDVGCSPAPPALCQSLVPYTGREPRKILLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQTVTIIAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNREMFGRMNDIRPVKVKRKKSFNLSRKFPFYKSKENIVQELVETEQCLTSNTSDSESSSKGQEDTILSYEPVIRQEIHYTRPVIILGPMKDRVNDDLISEFPHKFGSCVP--------HTTRPRRENEMDGQDYHFVGSREQMEKDIQDNKFIEAGQFNENLYGTSILSVRAVAER-GKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSVEALMELNKRQTYEQANKVFDKAMKLEQEFGEFFTAIVQGDSLDEIYNKIKLIIEEQSGPYIWIPSAEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63622-1", "uniprot_id": "DLG2_RAT", "id": "Q63622-1", "name": "Disks large homolog 2", "aln": "-----------------------------------------------------------MFFAC------------------------------------YCALRTN-VKKYRYQDEDGP-HDHSL-PRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHI--------------------------SPLKASPAP-------------IIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRP-------------------ILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNN----YSLEEVTHEEAVAILKNTSDVVYLKVGK-PTTIYMTDPYGPPDITH------SYSPPMENHLLS----GNNGTLEYKTSL---PPISPGRYS---------PIPKHMLVEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSTPYPHYHLGLLPDSDMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVILDGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLG------------------------------------------DDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAER-GKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XM9-1", "uniprot_id": "DLG2_MOUSE", "id": "Q91XM9-1", "name": "Disks large homolog 2", "aln": "-----------------------------------------------------------MFFAC------------------------------------YCALRTN-VKKYRYQDEDGP-HDHSL-PRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHI--------------------------SPLKASPAP-------------IIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRP-------------------ILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNN----YSLEEVTHEEAVAILKNTSDVVYLKVGK-PTTIYMTDPYGPPDITH------SYSPPMENHLLS----GNNGTLEYKTSL---PPISPGRYS---------PIPKHMLGEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSTPYPHYHLGLLPDSDMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLDGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLG------------------------------------------DDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAER-GKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15700-1", "uniprot_id": "DLG2_HUMAN", "id": "Q15700-1", "name": "Disks large homolog 2", "aln": "-----------------------------------------------------------MFFAC------------------------------------YCALRTN-VKKYRYQDEDAP-HDHSL-PRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHI--------------------------SPLKASPAP-------------IIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRP-------------------ILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNN----YSLEEVTHEEAVAILKNTSEVVYLKVGK-PTTIYMTDPYGPPDITH------SYSPPMENHLLS----GNNGTLEYKTSL---PPISPGRYS---------PIPKHMLVDDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKN------------------------KEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAER-GKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PYH7-1", "uniprot_id": "DLG2_DANRE", "id": "Q5PYH7-1", "name": "Disks large homolog 2", "aln": "----MKAVVRVLKLEERAVHRQQNRPPAVQGSQHQSHSPACMNPALMSSPWVRQKHGGRAIPNR------------------------------------LCLSTTDSPHSYRYQDDDSPPPEHSF-PRLTNEVRAPELVHVSEKNLSEIENVHGYVSHSHI--------------------------SPLKASPAP-------------IIVNTDTLESVPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNESDVSEVSHSKAVEALKAAGSIVRLYVRRRRP-------------------MLETVTEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNN----YTLEEVTHEEAVAILKNTSDVVYLKVGK-PTSVYLSDPYGPPDITH------SFSPAMENHISSP---GNNGTLEYKSSL---PPISPGRYS---------PLPKHLLGEEDINRNP-------------------------------------------SLDEMEGHRFDSQHFQLR------------EPRKIVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYRPEEYGRFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRALFDYERAKDSGLPSQGLSFRYGDILHVINASDDEWWQARRVTPEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGSLDSKGSFSEKRRKNFIFSRKFPFYKN------------------------KDADEQDGSDSERSQEELILSYEPVIRQEINYARPVIILGPMKDRINDDLISEFPDKFGSCVPPANSSDQEDTTRPKRDYEVDGRDYHFMASREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVKYVAER-GKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSIESLMEMNKRLTEEQAKKTYDRAMKLEQEFGEYFTALVQGDTLEDIYNQCKMVIEEQSGPYIWIPSKEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62696-1", "uniprot_id": "DLG1_RAT", "id": "Q62696-1", "name": "Disks large homolog 1", "aln": "MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVISIFQSNLFQALIDIQEFYEVTLLDNP--KCVDHS--KQCEPVQPGNPWESGSLSSAAVTSESLPGGLSPPVEKYRYQDEEVL-PSERISPQVPNEVLGPELVHVSEKSLSEIENVHGFVSHSHISPIKPT--EAVPP-SSPIVP--VTPALPVPAESPVVLPS-TPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK--------------------AFRKNHEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNS----VCLEEVTHEEAVTALKNTSDFVYLKAAK-PTSMYINDGYAPPDITN------SSSQSVDNHVSP----SSYLGQ---------TPASPARYS---------PISKAVLGDDEITR---------------------------------------------------------------------------EPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLRETMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYHEY---------------------------GCSKGGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEK-GKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTDEQARKTFERAVRLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811D0-1", "uniprot_id": "DLG1_MOUSE", "id": "Q811D0-1", "name": "Disks large homolog 1", "aln": "MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNP--KCVDHS--KQCEPVQPVTTWEIASLPSTAVTSETLPGSLSPPVEKYRYQDEEVL-PPEHISPQVTNEVLGPELVHVSEKNLSEIENVHGFVSHSHISPIKPT--EAVPP-SSPIVP--VTPALPVPAESTVVLPS-APQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRKP-------------------ASEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNS----VCLEEVTHEEAVTALKNTSDFVYLKVAK-PTSMYINDGYAPPDITN------SSSQSVDNHVSP----SSCLGQ---------TPTSPARYS---------PISKAVLGDDEITR---------------------------------------------------------------------------EPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYR----------------------------------GQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEK-GKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12959-1", "uniprot_id": "DLG1_HUMAN", "id": "Q12959-1", "name": "Disks large homolog 1", "aln": "MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNP--KCIDRS--KPSEPIQPVNTWEISSLPSSTVTSETLPSSLSPSVEKYRYQDEDTP-PQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKPT--EAVLP-SPPTVP--VIPVLPVPAENTVILPT-IPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKP-------------------VSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNN----VCLEEVTHEEAVTALKNTSDFVYLKVAK-PTSMYMNDGYAPPDITN------SSSQPVDNHVSP----SSFLGQ---------TPASPARYS---------PVSKAVLGDDEITR---------------------------------------------------------------------------EPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTR-DKGEIPDDMGSKGLKHVTSNASDSESSYR----------------------------------GQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEK-GKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PYH6-1", "uniprot_id": "DLG1_DANRE", "id": "Q5PYH6-1", "name": "Disks large homolog 1", "aln": "MPVRQKDAQRALQLLEEYQTKLSQTGDPHLRLSIERVINIFKSTLFQALVDIQEYYEVSLQDTED-KPIEDSSLKSRESFPPVNEWNLSVPPSTTGPTEPVPINLPQTEEKYRYQDEDTTSPPEHSSPHIPGDARPPELVQVSEKNISQIENVHGYVSHSHISPMKQA--DVIPPPSAPIIP--VIPISPVPAETTAIIPAPASQASPAPVVVNTESLDSSPYVNGTEADYEYEEITLERGNSGLGFSIAGGTDNPHIGEDPSIFITKIIPGGAAAQDGRLRVNDCILRVNDVDVRDVTHSNAVEALKEAGCIVRLYVRRRKP-------------------LSEKIMDVKLVKGPKGLGFSIAGGVGNQHIPGDNSIYITKIIEGGAAHKDGRLQIGDKLLAVNA----VCLEEVTHEDAVAALKNTPDVVYLKVAK-PTSVFMNDSYAPPDVTS------SYSQHMENHIST----QSYLSQPL-------TPATPSRYS---------PVSKGMLGDDEITR---------------------------------------------------------------------------EPRKIVLHRGTTGLGFNIVGGEDGEGIFISFILAGGPADLCGELRKGDRIVSVNGVDLRSATHEQAAAALKNAGQTVTIIAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRTLYVRALFDYDITKTVKFNSKSRD-------------------------------------KASLNDKRRKTLFSRKFLFSKNKDSGEQD---TSDVDQHVTSNASDSESSFR----------------------------------GQEDYVLSYETVTQQEVSYSRPVIILGPMKDRINDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVNSREQMEKDIQDHKFIEAGQYNNHLYGTSVQSVREVAEK-GKHCILDVSGNAIKRLQLAQLYPIAVFIKPKSVENILEMNKRLMEEQGRKTYDRAMKLEQEFLEHFTAIVQGDTLEEIYNQVKQIIEEQSGPFIWVPVKEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5PYH5-1", "uniprot_id": "DLG1L_DANRE", "id": "Q5PYH5-1", "name": "Discs large homolog 1-like protein", "aln": "-------MSPSIKKLDCFSPMLCHCKVACTNSTIS---------------------------------------------------------------------LMFGCKKYRHQDEDTGSPQEPSSPQFTDDTPGPELVQVAEKSLSQIENVHGFVAHSHISPMKVESLECIFDGPSPVVKEESPPSPSTPLSNPYPQSPVSVQANPPPVVVNTESLDSAPYVNGTEADFEYEEITLERGNSGLGFSIAGGTDNPHIGEDPSIFITKVIPGGAAAQDGRLRVNDVILRVNEVDVRDVTHSKAVEALKEAGSLVRLYVRRRKS-------------------ASEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNS----SCLEEVTHEHAVTALKNTPDVVYLKVAK-PNSVFMNDSFAPPDITN------SYSQHMENHISP----PSYLSQPL-------PPVHSGRFS---------PTPKTTVGDDDVTR---------------------------------------------------------------------------EPRKVVLHRGTTGLGFNIVGGEDGEGIFISFILAGGPADLCGELRKGDRLVSVNGIDLRGATHEQAAAALKNAGQTVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVVNASDDEWWQARQVTAQGEVEEMGVIPSKRRVEKKERARLKTVKFNSKSR-EKGDNPDDMLSKGQS------------------------------------------------GQEEYVLSYEPVSQQEVNYSRPVIILGPMKDRVNDDLISEFPDKFGSCVP--------HTTRPKRDYEVDGRDYHFVVSREQMERDIQEHKFIEAGQYNSHLYGTSVQSVREVAEK-GKHCILDVSGNAIKRLQVAMLYPIGIFIKPKSVENIMEMNKRLTEEQGRKTYDRAMKLEQEFMEHFTAIVQGDTLEEIYDQVKQIIEEQSGPYIWVQSKEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P78352-1", "uniprot_id": "DLG4_HUMAN", "id": "P78352-1", "name": "Disks large homolog 4", "aln": "----------------------------------------------------------------------------------------------------MDCLCIVTTKKYRYQDEDTP-PLEHSPAHLPN---------------------QANSP-------------------------------PVIVNTDT-----------------LEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKP-------------------PAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS----VGLEDVMHEDAVAALKNTYDVVYLKVAK-PSNAYLSDSYAPPDITT------SYSQHLDNEISHSSYLGTDYPTAM-------TPTSPRRYS---------PVAKDLLGEEDIPR---------------------------------------------------------------------------EPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSG--------------------------------------------------------------SQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVP--------HTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ-GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31016-1", "uniprot_id": "DLG4_RAT", "id": "P31016-1", "name": "Disks large homolog 4", "aln": "----------------------------------------------------------------------------------------------------MDCLCIVTTKKYRYQDEDTP-PLEHSPAHLPN---------------------QANSP-------------------------------PVIVNTDT-----------------LEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKP-------------------PAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS----VGLEDVMHEDAVAALKNTYDVVYLKVAK-PSNAYLSDSYAPPDITT------SYSQHLDNEISHSSYLGTDYPTAM-------TPTSPRRYS---------PVAKDLLGEEDIPR---------------------------------------------------------------------------EPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSG--------------------------------------------------------------SQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVP--------HTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ-GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62108-1", "uniprot_id": "DLG4_MOUSE", "id": "Q62108-1", "name": "Disks large homolog 4", "aln": "----------------------------------------------------------------------------------------------------MDCLCIVTTKKYRYQDEDTP-PLEHSPAHLPN---------------------QANSP-------------------------------PVIVNTDT-----------------LEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKP-------------------PAEKIIEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS----VGLEDVMHEDAVAALKNTYDVVYLKVAK-PSNAYLSDSYAPPDITT------SYSQHLDNEISHSSYLGTDYPTAM-------TPTSPRRYS---------PVAKDLLGEEDIPR---------------------------------------------------------------------------EPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFHFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSG--------------------------------------------------------------SQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVP--------HTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ-GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6R005-1", "uniprot_id": "DLG4_DANRE", "id": "Q6R005-1", "name": "Disks large homolog 4", "aln": "MPLKREDTERALQAMEACQ----SAGDEGFRTRAERLLTIFQSDLFQALLDIQEFYELTVFENQ------------------------------------TAGRALTPGLKYRYHDEETP-PLQHSPAHLSTGK-SAEMLHLGDSGHAPIDGIHAYTPQMHVS-----------------------PAKPVLLPSGH-----------------APYYATSTLMNGMDGDVEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNDVDVREVTHSFAVEALKEAGPIVRLYVLRHKP-------------------SAEKITELKLIKGPKGLGFSIAGGVGNQHVPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNN----MYLEEVMHEDAVAALKNTGDVVFLRVAKTLHQHHHQDAYNPPDITS------SYSPHMD---------MSDYPQAL-------SPSSPRRYS---------PIPKGLFLDDDISR---------------------------------------------------------------------------EPRRVVIHRGSTGLGFNIVGGEDGEGIFISFILAGGAADLSGELRKGDQILSVNGVDLRHATHEQAAAALKNAGQTVTIITQYRPEEYSRFEAKIHDLREQLMNSSLVSAAASLRSG-KRSFFIRALFDYDKTADGGFLSQAVSFRFGDVLQVFDCSDEEWWQAGKLAPHGELEETGYIPSKRRVERKEWSRLKTRGREPVS-----------------------------------------------------------------GRSDYIVSYETVTQSEVHYARPVIILGPSKDRVNDDLLSEFPDKFGSCVP--------HTTRPKREYEMDGRDYHFVSSREQMEKDIQSHRFIEAGQYNSHLYGTSVQSVRQVAEQQGKHCILDVSANAVRRLQAAQLYPIAIFIRPSSLQNVLNISKRLTEEQARRALDRAVKLEQDFIECFSAIVEGESFEEIYHHVKSVIEEQSGPYIWIPARERL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31007-2", "uniprot_id": "DLG1_DROME", "id": "P31007-2", "name": "Disks large 1 tumor suppressor protein", "aln": "MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADFIKSSNLNRNCAYEFNNDASSNQTNQSALNQNPIANNVSAQAQAEALSRTFKSELEEILNQRMRIESDTENAKEPT------------------VEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDD-SWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSG----QQLSQSQSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITR---------------------------------------------------------------------------EPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGT-LLRTTQKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEK--------NEDGSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLSINYTRPVIILGPLKDRINDDLISEYPDKFGSCVP--------HTTRPKREYEVDGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEK-GKHCILDVSGNAIKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :** : :*:* *************** ****: *..*:***:*.***** **** :** :: **: .* :* *: **:*** ** :*:* * *:: . ::.*.** **********:****:****.**:**:::****: **:*. **::: *. *::* ** **: **. : * * .* . . : . . . *:: * . . :: *** : :::*. ************:**::*******.*** .**::**:::***.::* *:**:** *** :* **:::**:**:* ***::*::*:: : *.: **: ** :::**:***: : *:. * : : : . .: ::***.* : .: *:**:***** *** ****:**:*.******* .****:*: *:**:****: ***:**:*** : ******:*.:*****: **: ***: *********.**::*** * *:*:.:**:* *:: ::::.:* **..: ::* ::**:* * *:.:*:*:::::** : * :* . ** **: * *", "identical_positions": 281, "similar_positions": 174, "identity": "25.87%" }, { "cls_id": "homologset.agr.FB:FBgn0001941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q564G3-1", "uniprot_id": "DEGS2_RAT", "id": "Q564G3-1", "name": "Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGNSAA---------------RSDFEWVYSDQPHTQR---RKEMLAKYPSIKALMRPDPNIKWTVLGMVLVQVLACWLVRGLSWRWLLFWAYAFGGCINHSLTLAIHDISHNTAFGTRCASRNRWFAVFANLPIGLPYATSFKKYHVDHHRYLGGDGLDVDIPTDFEGWFFCTPARKLLWLVLQPFFYSLRPLYVNPKAVTRMEILNALVQLAFNVTIFALWGIKAIVYLLASSLLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHVEHHDFPSIPGCYLPLVRMIAPEYYDHLPQHHSWVKVLWDFVFEDSLGPYSRVKRKCKLAKDQL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2F2-1", "uniprot_id": "DEGS2_MOUSE", "id": "Q8R2F2-1", "name": "Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGNSAA---------------RSDFEWVYSDQPHTQR---RKEMLAKYPAIKALMRPDPHIKWTVSGMVLVQVLACWLVRGLSWRWLLFWAYAFGGCINHSLTLAIHDISHNTAFGTSCVSRNRWFAIFANLPIGLPYATSFKKYHVDHHRYLGGDGLDVDIPTNFEGWFFCTPARKLLWLVLQPFFYSLRPLCVNPKVVTRMEILNALVQLAFDVTIFALWGIKPIVYLLGSSLLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHMEHHDFPSIPGYYLPLVRKIAPEYYDHLPQHHSWVKVLWDFVFEDSMGPYSRVKRKCKLAKDHL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QHC5-1", "uniprot_id": "DEGS2_HUMAN", "id": "Q6QHC5-1", "name": "Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGNSAS---------------RSDFEWVYTDQPHTQR---RKEILAKYPAIKALMRPDPRLKWAVLVLVLVQMLACWLVRGLAWRWLLFWAYAFGGCVNHSLTLAIHDISHNAAFGTGRAARNRWLAVFANLPVGVPYAASFKKYHVDHHRYLGGDGLDVDVPTRLEGWFFCTPARKLLWLVLQPFFYSLRPLCVHPKAVTRMEVLNTLVQLAADLAIFALWGLKPVVYLLASSFLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHVEHHDFPSIPGYNLPLVRKIAPEYYDHLPQHHSWVKVLWDFVFEDSLGPYARVKRVYRLAKDGL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R9Z4-1", "uniprot_id": "M0R9Z4_RAT", "id": "M0R9Z4-1", "name": "", "aln": "MHTLGLLLVFMAPTPSPTPCSSASLLARSSLLALLNLLLSVSALDSSRGLCLLSPSYLHIYSTAFPFTSRVMEQSRVHMLTGVVWLELVLASLLGFVIYWFVSRDKEETLPLGDGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDRFRASPPLEGSRFHYGFNSIYLKKVVSYWRIEFDWRKQVEILNQYPHFKTKIEAKYPEIKSLMKPDRNLIWIVTAIVLTQLASLYLVKDLDWKRLIFCAYVFGGSINHSLILGSPEICHNFPFGHHRALWNRWFRIFANLPIGVLYSISFKRYHMDHHRYLGADGIDVGVPRDLEGWFFCTTFRRLVWVAFQPLFITFRPLFINPKPISDLETINAVAQIAFDLIVYSVFGIKSLVYMLASSMLGLGLHPISGNLIGDHCLFLKEHKT-FYYGPLNLLTFNVGYPTEHHDFPNIPGKDLPLVRKIAAEYYDKLPHHISWVKVLYDFVMDNTINPYSPKKMLPEGK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZXB2-1", "uniprot_id": "D3ZXB2_RAT", "id": "D3ZXB2-1", "name": "Sphingolipid delta(4)-desaturase DES1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGSRVS---------------REDFEWVYTDEPHAQR---RREILAKYPEIKSLMKPDPNLIWIITAMILVQLASFYLVKDLEWKWLIFWSYVFGSSINHSMTLAIHEISHNFPFGHHRALWNRWFGIFTNLPFGIPYSISYKMYHIDHHRYLGTAGIDVDAPSDLEGWFFCTTFRKLVWVAFQPFFLLFRPYFVNPKPMTYLETINIMSQITFNIVIYHVWGIKSLVYMLAASLLGLGLNPISGHFIADHFMFSKGQDTNSYYGPLNFFMFNGGYHNEHHDFPSIPGSRLPQVRKIAAEYYDELPHHTSWVKVLYDFVTDDTMSPYSRIKRPPKGNEVLHK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XIF5-1", "uniprot_id": "DEGS1_RAT", "id": "Q5XIF5-1", "name": "Sphingolipid delta(4)-desaturase DES1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGNRVS---------------REEFEWVYTDQPHAAR---RQEILAKYPEIKSLMKPDPNLIWIVTSMLLVQLASFYLVKDLDWKWLMFWSYAFGSCLNHSMTLAIHEISHNFPFGHHKAMWNRWFGMFANLSLGVPYSISFKRYHMDHHRYLGADGIDVDIPTDFEGWFFCTTLRKLVWVILQPLFYAFRPLFINPKPITHLEVINTVIQVTFDVLVYYVFGVKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNVPGKNLPLVRKIASEYYDNLPHYNSWIRVLYDFVMDDTISPYSRMKRPPKGNEIQE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09005-1", "uniprot_id": "DEGS1_MOUSE", "id": "O09005-1", "name": "Sphingolipid delta(4)-desaturase DES1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGSRVS---------------REEFEWVYTDQPHAAR---RKEILAKYPEIKSLMKPDHNLIWIVAMMLLVQLASFYLVKDLDWKWVIFWSYVFGSCLNHSMTLAIHEISHNFPFGHHKALWNRWFGMFANLSLGVPYSISFKRYHMDHHRYLGADKIDVDIPTDFEGWFFCTTFRKFVWVILQPLFYAFRPLFINPKPITYLEIINTVIQITFDIIIYYVFGVKSLVYMLAATLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNVPGKNLPMVRKIASEYYDDLPHYNSWIKVLYDFVTDDTISPYSRMKRPPKGNEILE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15121-1", "uniprot_id": "DEGS1_HUMAN", "id": "O15121-1", "name": "Sphingolipid delta(4)-desaturase DES1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGSRVS---------------REDFEWVYTDQPHADR---RREILAKYPEIKSLMKPDPNLIWIIIMMVLTQLGAFYIVKDLDWKWVIFGAYAFGSCINHSMTLAIHEIAHNAAFGNCKAMWNRWFGMFANLPIGIPYSISFKRYHMDHHRYLGADGVDVDIPTDFEGWFFCTAFRKFIWVILQPLFYAFRPLFINPKPITYLEVINTVAQVTFDILIYYFLGIKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNIPGKSLPLVRKIAAEYYDNLPHYNSWIKVLYDFVMDDTISPYSRMKRHQKGEMVLE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94515-1", "uniprot_id": "DEGS1_DROME", "id": "Q94515-1", "name": "Sphingolipid delta(4)-desaturase DES1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGQKVS---------------RTDFEWVYTEEPHASR---RKIILEKYPQIKKLFGHDPNFKWVAGAMVLTQILALFVVKDLSWSWLIVAAYCFGGIINHSLMLAVHEISHNLAFGHSRPMHNRILGFICNLPIGLPMSISFKKYHLEHHRYQGDEAIDTDIPTLLEARLFDTTFGKFLWVCLQPFFYIFRPLIINPKPPTRLEIINTVVQLTFNALIVYFLGWKPLAYLLIGSILAMGLHPVAGHFISEHYMFAKGFETYSYYGPLNWITFNVGYHNEHHDFPAVPGSRLPEVKRIAKEFYDTMPQHTSWTRVLYDFIMDPAVGPYARVKRRQRGLAS---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * :*:* : : : *** ** *: * .: * ::*.*: : ::*:.* * ::. :* **. :***: *. :*.** .** ** : .: **..*: : *:* **::**** * :*.. * :*. :* *. :::*: :**:* :** ::** : :* :* : *:: : : . * *.:.*:* .::*.:**:*::*:::.:* :* * .* ****** : ** ** ****** :** ** *: ** *:** :*:: ** :**:**: : ::.**: * . ", "identical_positions": 108, "similar_positions": 99, "identity": "21.56%" }, { "cls_id": "homologset.agr.FB:FBgn0001942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10630-1", "uniprot_id": "IF4A2_MOUSE", "id": "P10630-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "--MSGGS----ADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14240-1", "uniprot_id": "IF4A2_HUMAN", "id": "Q14240-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "--MSGGS----ADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RKI1-1", "uniprot_id": "IF4A2_RAT", "id": "Q5RKI1-1", "name": "Eukaryotic initiation factor 4A-II", "aln": "--MSGGS----ADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60843-1", "uniprot_id": "IF4A1_MOUSE", "id": "P60843-1", "name": "Eukaryotic initiation factor 4A-I", "aln": "--MSAS-----QDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60842-1", "uniprot_id": "IF4A1_HUMAN", "id": "P60842-1", "name": "Eukaryotic initiation factor 4A-I", "aln": "--MSAS-----QDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GF11-1", "uniprot_id": "A0A8I6GF11_RAT", "id": "A0A8I6GF11-1", "name": "RNA helicase", "aln": "LSTTASPPNSFSDSRPRDNGPDGMEPEGVIESNWNETVDSFEDKNLSESLLRGMYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGSGKTATFAISILQQIELDLKATQALVLAPTSELAQQIQKVVMALGDYMGASCHACIEGTNVRAEVQKLQMEAPHIIMGTPGRVFDMLNWRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVILINTRRKVDWLAEKMHARDFTVSAM--------------EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYVHRIGRGGQFGRKGVASNMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F7F7A6-1", "uniprot_id": "F7F7A6_RAT", "id": "F7F7A6-1", "name": "RNA helicase", "aln": "--MWAWQQRPHLGAVSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02748-1", "uniprot_id": "IF4A_DROME", "id": "Q02748-1", "name": "Eukaryotic initiation factor 4A", "aln": "--MDDRN-------EIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVREDARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10081-1", "uniprot_id": "IF4A_YEAST", "id": "P10081-1", "name": "ATP-dependent RNA helicase eIF4A", "aln": "----------------MSEGITDIE-ESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ--IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:: :. *::.:.: .*:* :* *.****::.****:*********:* :.* **:******:***.**:*: **::: ..: ***:**** *** ***:*::**. :* **** **.. : . *. :::******:* :: : : .. **:*:********* ***:** ::* * . **:******* *****: ***:*: *****:*******:***:**:.*::* * ***:::::**:**: ******: *: :: .*****: :*******:**:**********************:*:***:*******:******* *::*::* ::::* ** * :**:* ::* *: ", "identical_positions": 209, "similar_positions": 104, "identity": "50.48%" }, { "cls_id": "homologset.agr.FB:FBgn0001961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PD4-1", "uniprot_id": "ARC1A_RAT", "id": "Q99PD4-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLF---------------NYD-DRGCLTFVSKLDVP----KQSIQRNMSAMERFRNMDKRATTED---RNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q6-1", "uniprot_id": "ARC1A_MOUSE", "id": "Q9R0Q6-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLF---------------NYD-DRGCLTFVSKLDVP----KQSIQRNMSAMERFRNMDKRATTED---RNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92747-1", "uniprot_id": "ARC1A_HUMAN", "id": "Q92747-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLF---------------NYD-DRGCLTFVSKLDIP----KQSIQRNMSAMERFRNMDKRATTED---RNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WV32-1", "uniprot_id": "ARC1B_MOUSE", "id": "Q9WV32-1", "name": "Actin-related protein 2/3 complex subunit 1B", "aln": "---------MAYHSF--LVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWNKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTL-KGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVE--ERPAPTPWGSKMPFGELM--FESSSS--CGWVHGVCFSASGSRVAWVSHDSTVCLVDADKKMAVATLASETLPLLAVTFITENSLVAAGHDCFPVLF---------------TYDNAAVTLSFGGRLDVP----KQSSQRGMTARERFQNLDKKASSEGGAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKS--LESALKDLKIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88656-1", "uniprot_id": "ARC1B_RAT", "id": "O88656-1", "name": "Actin-related protein 2/3 complex subunit 1B", "aln": "---------MAYHSF--LVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWNKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTL-KGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVE--ERPAPTPWGSKMPFGELM--FESSSS--CGWVHGVCFSAGGSRVAWVSHDSTVCLVDAEKKMAVATLASETLPLLAITFITENSLVAAGHDCFPVLF---------------TYDNAAGTLSFGGRLDVP----KQNSQRGLTARERFQNLDKKASSEGGAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKS--LESALKDLKIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15143-1", "uniprot_id": "ARC1B_HUMAN", "id": "O15143-1", "name": "Actin-related protein 2/3 complex subunit 1B", "aln": "---------MAYHSF--LVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTL-KGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVE--ERPAPTPWGSKMPFGELM--FESSSS--CGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLLALTFITDNSLVAAGHDCFPVLF---------------TYDAAAGMLSFGGRLDVP----KQSSQRGLTARERFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKS--LESALKDLKIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97182-1", "uniprot_id": "O97182_DROME", "id": "O97182-1", "name": "Actin-related protein 2/3 complex subunit", "aln": "--------MAETYTFGTSLASITCHAWNKDRTQIALSPNNHEIHIYSREGSDWKLADVLNQHDLRVMGIDWAKNTNRIVSCAADRNAYVWTQGDDGKWKPALVLLRINRAATCVKWSPAENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVTSLDWHPNNVLLLAGSTDYKVRVFSAFIKDIE--EPPTPTPWGNRKPLGQLMAEFRNSQTSGGGWINSVSFSSDGNKVCWVGHDSCVSIADATNGNTVIRCRTGYLPFLSCEWVSPTSVVVAGYSCVPLLY---------------SLT-ADGKLVLSGKLDKS----QKKESSGITAMRIFQSMDRNMRTEN---TDTVVDSIHQNAITSVRLYAGDKASATKVSTSGVDGQLVIWNVEQGGINGGMRNLQI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38328-1", "uniprot_id": "ARPC1_YEAST", "id": "P38328-1", "name": "Actin-related protein 2/3 complex subunit 1", "aln": "MSFSNSKDKSVVAVYKLVKAPIYSHCFSQDKSILAVTCETDCLVYRVSNNTPPVLFATLKDHDKTITAVDISIHG-RIVTCSQDRNAYVWEPLSDGTYKPTLVLLRINRAATSVTWAPNGYKFAVGSSARIIAVCYYEHENNWWVSKHIKKPIKSTINCLSWHANGVLLAAGGTDGFMRVFSGFIKGLDSKESVAGSPWGQKFPFGCLIREWYQGSY-----IHDVEWRSQMERIAYVAHDGTLNVVDYQSPVQSVN-APEGLPYRSLVWINDHEIVCGGYSCHPVLFSEASEGWKFAKNLDKSDNNKSSALTASGNTDELSGNNDESSTFGISALRKFKELDLKGKVST-----DVQESAHENAIVELRPFAESNGQITQVSSCGLDGKIVIYTI---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* .*.:.:*:: :*: :.. : ..: *::*: : .:* : . ***:*. ******* .. :**:**:******* * *:* ******.:*:*::**:* **:***.*******:**: .*.**.*.*** **. * *:**.:** :: * : :***.: *:* *: : . ::.* : : .::.:*.**. : :.* . . ** : ::. .:* .*:.* *:*: . * .. * .:. .::* . *:.:* . . :: *:*:: .: .: . :..: *:** : *: . ", "identical_positions": 102, "similar_positions": 123, "identity": "24.82%" }, { "cls_id": "homologset.agr.FB:FBgn0001965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02384-1", "uniprot_id": "SOS2_MOUSE", "id": "Q02384-1", "name": "Son of sevenless homolog 2", "aln": "-------------------------------------------------------------MQQAPQPYEFFSEENSPK-------------WR--------GLLVPALR--------------------------------------------KVQEQVHPTLSANEESLYYIEELIFQLLNKLCMAQ-PRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLK-EVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDD-IGLVSLCEDEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLLDRKLFKPSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLP-RLMLVPVYHCWHYFELLKQLKACSEEQEDKECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGPLTRIGAKH----ERHIFLFDG---LMISCKPN-HGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYRHAFELVSKDENSVIFAAKSAE--------------EKNNWMAALISLHYRSTLDR------MLDSVLLKEENEQPLRLP------------SPDMYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLN-LLIERFEIPEPEPTEADKLALEKG----------------EQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHYYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIKRKKQ---AQANGISHNITFESSPPPVEWHISRTGQFETFDLMTLHP----IEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT---------LWFEKCIVEAENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFEN--LNPMGILSEKEFTDYLFNKSLEIEPRNCKQPPRFPRKS-TFSLKSPGIRP-------------------------------------------------NAGRHGSTSGTLRGHPTPLE-------------REPYKISFS------RIAETELESTVSAPTSPNTP-------STPPVSASSDHSVFLDVDLNSSCGSNTIFAP---------------------------------VLLPHSKTFFSSCGSLHKLS---------------------------------------EEPLIPPPLPPRKK---FDHDALNSKGAVKSDDDPPAIPPR--QPPPPKVKPRVPVLMG-TFDGPVP--------------------------------SPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVST--CPNSPSTPPTTPSPRIPRSC-------HLLSS---SHSSLAHLPAPPVPPRQNSS-------------------PLLPKLPPKTYKRELSHPPLYR--LPLLENAETPQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1M3-1", "uniprot_id": "A0ABK0M1M3_RAT", "id": "A0ABK0M1M3-1", "name": "", "aln": "--------------------MSFSPHIRVLPSRAAVTAPGSPRAARIRFVCRDSDAAAECVWNSRPAPAHVPRRDRLPSRPPGPAPG----AWARSAARMLGAGLLPRLGRASAGPSRAAAAGTRRSAAARGAGGAASAVHAGHARPLGPEGPLEVQEQVHPTLSANEESLYYIEELIFQLLNKLCLAQ-PRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLK-EVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDD-IGLVSLCEEEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLP-RLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGPLTRIGAKH----ERHIFLFDG---LMISCKPN-HCQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYKHAFELVSKDENSVIFAAKSAE--------------EKNNWMAALISLHYRSTLDR------MLDSVLLKEENEQPLRLP------------RPDVYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLS-LLIERFEIPDPEPTEADKLALEKG----------------EQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEAFISSVRGKAMKKWVESIAKIIKRKKQ---AQANGVSHNITFESPPPPVEWHISRAGQSETFDLMTLHP----IEIARQLTLLESDLYRRVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT---------LWFEKCIVEAENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRVLDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFEN--LNPMGLLSEKEFTDYLFNKSHEIEPRNCKQPPRFPRKS-TFSLKSPGIRP-------------------------------------------------NASRHGSTSGTFRGHPTPLE-------------REPYKISFS------RIAETELESTVSAPTSPNTP-------STPPVSASSDHSVFLDVDLNSSCGSNTIFAP---------------------------------VLLPHSKSFFSSCGSLHKLS---------------------------------------EEPLVPPPLPPRKK---FDHDAPNSKGAMKSDDDPPAIPPR--QPPPPKVKPRAPVLTG-TFEGPVP--------------------------------SPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVST--CPNSPSTPPPTPSPRIPRRC-------HLPSP---SHNNLAHPPAPPVPPRQNSS-------------------PHLPKLPPKTYKRELSHPPLYR--LPLFENAETPQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07890-1", "uniprot_id": "SOS2_HUMAN", "id": "Q07890-1", "name": "Son of sevenless homolog 2", "aln": "-------------------------------------------------------------MQQAPQPYEFFSEENSPK-------------WR--------GLLVSALR--------------------------------------------KVQEQVHPTLSANEESLYYIEELIFQLLNKLCMAQ-PRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLK-EVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD--IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLP-RLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYSHQLRSKHLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGPLTRIGAKH----ERHIFLFDG---LMISCKPN-HGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDTCEHKHAFELVSKDENSIIFAAKSAE--------------EKNNWMAALISLHYRSTLDR------MLDSVLLKEENEQPLRLP------------SPEVYRFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLS-LLIERFEIPEPEPTDADKLAIEKG----------------EQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQ---AQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHP----IEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT---------LWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFEN--LNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKS-TFSLKSPGIRP-------------------------------------------------NTGRHGSTSGTLRGHPTPLE-------------REPCKISFS------RIAETELESTVSAPTSPNTP-------STPPVSASSDLSVFLDVDLNSSCGSNSIFAP---------------------------------VLLPHSKSFFSSCGSLHKLS---------------------------------------EEPLIPPPLPPRKK---FDHDASNSKGNMKSDDDPPAIPPR--QPPPPKVKPRVPVPTG-AFDGPLH--------------------------------SPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDIST--CPNSPSTPPSTPSPRVPRRC-------YVLSS---SQNNLAHPPAPPVPPRQNSS-------------------PHLPKLPPKTYKRELSHPPLYR--LPLLENAETPQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62245-1", "uniprot_id": "SOS1_MOUSE", "id": "Q62245-1", "name": "Son of sevenless homolog 1", "aln": "-------------------------------------------------------------MQAQQLPYEFFSEENAPK-------------WR--------GLLVPALK--------------------------------------------KVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQ-PRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLR-EVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSNDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHGHFLSQLSKPGAALYLQSIGEGFKEAVQYVLP-RLLLAPVYHCLHYFELLKQLEEKSEDQEDKECMKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGTLTRVGAKH----ERHIFLFDG---LMICCKSN-HGQPRLPGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAE--------------EKNNWMAALISLQYRSTLER------MLDVTVLQEEKEEQMRLP------------SAEVYRFAEPDSEENILFEENVQPKAGIPIIKAGTVLKLIERLTYHMYADPNFVRTFLTTYRSFCRPQELLS-LLIERFEIPEPEPTEADRIAIENG----------------DQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKI---ARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHP----IEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT---------LWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSKRRRVAEITGEIQQYQNQPYCLRVEPDIKRFFEN--LNPMGNSMEKEFTDYLFNKSLEIEPRHPKPLPRFPKKY-SYPLKSPGVRP-------------------------------------------------SNPRP----GTMR-HPTPLQ-------------QEPRKISYS------RIPESETESTASAPNSPRTP-------LTPPPASGTSSNTDVCSVFDSDHSASPFHS----------------------------------------RSASVSSISLSKGT---------------------------------------DEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPR--QPTSKAYSPRYSISDRTSISDPPE--------------------------------SPPLLPPRE---------PVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSP--SPFTP-PPPQTPSPHGTRR--------HLPSPPLTQEMDLHSIAGPPVPPRQSTS-------------------QLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3T0-1", "uniprot_id": "D4A3T0_RAT", "id": "D4A3T0-1", "name": "", "aln": "-------------------------------------------------------------MQAQQLPYEFFSEENAPK-------------WR--------GLLVPALK--------------------------------------------KVQGQVHPTLESNEDALQYVEELILQLLNMLCQAQ-PRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLR-EVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSYDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDVLRPGFHERFLSQLSKPGAALYLQSIGEGFKEAVQYVLP-RLLLAPVYHCLHYFELLKQLEEKSEDQEDKECMKQAITALLNVQSGMEKICSKNLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGTLTRVGAKH----ERHIFLFDG---LMICCKSN-HGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAE--------------EKNNWMAALISLQYRSTLER------MLDVTMLQEEKEEHMRLP------------SADVYRFAEPDSEENILFEENVQPKAGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLN-LLIERFEIPEPEPTEADRIAIENG----------------DQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDVDLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKI---ARDNGPGHNITFQNSPPTVEWHISRPGHIETFDLLTLHP----IEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT---------LWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSKRRRVAEITGEIQQYQNQPYCLRVESDIKRFFEN--LNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKY-SYPLKSPGVRP-------------------------------------------------SNPRP----GTMR-HPTPLQ-------------QEPRKISYS------RIPESETESTASAPNSPRTP-------LTPPPASSASSNTDVCSVFDSDHSASPFHS----------------------------------------RSASVSSISLSKGT---------------------------------------EEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPR--QPTSKAYSPRYSISDRTSISDPPE--------------------------------SPPLLPPRE---------PVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSP--SPFTP-PPPQTPSPHGTRR--------HLPSPPLTQEVDLHSIAGPPVPPRQSTS-------------------QLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07889-1", "uniprot_id": "SOS1_HUMAN", "id": "Q07889-1", "name": "Son of sevenless homolog 1", "aln": "-------------------------------------------------------------MQAQQLPYEFFSEENAPK-------------WR--------GLLVPALK--------------------------------------------KVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQ-PRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLK-EVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLP-RLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGTLTRVGAKH----ERHIFLFDG---LMICCKSN-HGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAE--------------EKNNWMAALISLQYRSTLER------MLDVTMLQEEKEEQMRLP------------SADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLS-LIIERFEIPEPEPTEADRIAIENG----------------DQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKI---ARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHP----IEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT---------LWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFEN--LNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKY-SYPLKSPGVRP-------------------------------------------------SNPRP----GTMR-HPTPLQ-------------QEPRKISYS------RIPESETESTASAPNSPRTP-------LTPPPASGASSTTDVCSVFDSDHSS-PFHSSN-------------------------DTVFIQVTLPHGPRSASVSSISLTKGT---------------------------------------DEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPR--QPTSKAYSPRYSISDRTSISDPPE--------------------------------SPPLLPPRE---------PVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSP--SPFTP-PPPQTPSPHGTRR--------HLPSPPLTQEVDLHSIAGPPVPPRQSTS-------------------QHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26675-1", "uniprot_id": "SOS_DROME", "id": "P26675-1", "name": "Protein son of sevenless", "aln": "-----------MFSGPSGHAHTISYGGGIGLGTGGGGGSGGSGSGSQGGGGGIGIGGGGVAGLQDCDGYDFTKCENAAR-------------WR--------GLFTPSLK--------------------------------------------KVLEQVHPRVTAKEDALLYVEKLCLRLLAMLCAKPLPHSVQDVEEKVNKSFPAPIDQWALNEAKEVINSKKRKS--VLPTEKVHTLLQKDVLQYKIDSSVSAFLVAVLEYISADILKMAGDYVIKIAHCEITKEDIEVVMNADRVLMDMLNQSEAHILPSPLS--LPAQRASATYEETVKELIHDEKQYQRDLHMIIRVFREELVK--IVSDPRELEPIFSNIMDIYEVTVTLLGSLEDVIEMSQEQS-APCVGSCFEELAEAEEFDVYKKYAYDVTSQASRDALNNLLSKPGASS-LTTAGHGFRDAVKYYLP-KLLLVPICHAFVYFDYIKHLKDLSSSQDDIESFEQVQGLLHPLHCDLEKVMASLSKERQVP------VSGRVR-RQLAIERTRELQMKVEHWEDKDVG--QNCNEFIREDSLSKLGSGKRIWSERKVFLFDG---LMVLCKANTKKQTPSAGATAYDYRLKEKYFMRRVDINDRPDSDDLKNSFELAPRMQPPIVLTAKNAQ--------------HKHDWMADLLMVITKSMLDR------HLDSILQDIERKHPLRMP------------SPEIYKFAVPDSGDNIVLEE--RESAGVPMIKGATLCKLIERLTYHIYADPTFVRTFLTTYRYFCSPQQLLQ-LLVERFNIPDPSLVYQDTGTAGAGGMGGVGGDKE-----HKNSHREDWKRYRKEYVQPVQFRVLNVLRHWVDHHFYDFEKDPMLLEKLLNFLEHVNGKSMRKWVDSVLKIVQRKNE---QEKSNKKIVYAYGHDPPPIEHHLSVPN--DEITLLTLHP----LELARQLTLLEFEMYKNVKPSELVGSPWTKKDKEVKSPNLLKIMKHTTNVT---------RWIEKSITEAENYEERLAIMQRAIEVMMVMLELNNFNGILSIVAAMGTASVYRLRWTFQGLPERYRKFLEECRELSDDHLKKYQERLRSINPPCVPFFGRYLTNILHLEEGNPDLLAN--TELINFSKRRKVAEIIGEIQQYQNQPYCLNEESTIRQFFEQ--LDPFNGLSDKQMSDYLYNESLRIEPRGCKTVPKFPRKWPHIPLKSPGIKPRRQNQTNSSSKLSNSTSSVAAAAAASSTATSIATASAPSLHASSIMDAPTAAAANAGSGTLAGEQSPQHNPHAFSVFAPVIIPERNTSSWSGTPQHTRTDQNNGEVSVPAPHLPKKPGAHVWANNNSTLASASAMDVVFSPALPEHLPPQSLPDSNPFASDTEAPPSPLPKLVVSPRHETGNRSPFHGRMQNSPTHSTASTVTLTGMSTSGGEEFCAGGFYFNSAHQGQPGAVPISPHVNVPMATNMEYRAVPPPLPPRRK---ERTESCADMAQKRQAPDAPTLPPRDGELSPPPIPPRLNHSTGISYLRQSHGKSKEFVGNSSLLLPNTSSIMIRRNSAIEKRAAATSQPNQAAAGPISTTLVTVSQAVATDEPLPLPISPAASSSTTTSPLTPAMSPMSPNIPSHPVESTSSSYAHQLRMRQQQQQQTHPAIYSQHHQHHATHLPHHPHQHHSNPTQSRSSPKEFFPIATSLEGTPKLPPKPSLSANFYNNPDKGTMFLYPSTNEE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04821-1", "uniprot_id": "CDC25_YEAST", "id": "P04821-1", "name": "Cell division control protein 25", "aln": "MSDTNTSIPNTSSAREAGNASQTPSISSSSNTSTTTNTESSSASLSSSPSTSELTSIRPIGIVVAAYDFNYPIKKDSSSQLLSVQQGETIYILNKNSSGWWDGLVIDDSNGKVNRGWFPQNFG------------------------------RPLRDSHLRKHSHPMKKYSSSKSSRRSSLNSLGNSAYLHVPRNPSKSRRGSSTLSASLSNAHNAETSSGHNNTVSMNNSPFSAPNDASHITPQSSNFNSNASLSQDMTKSADGSSEMNTNAIMNNNETNLQTSGEKAGPPLVAEETIKILPLEEIEMIINGIRSNIASTWSPIPLITKTSDYKLVYYNKDLDIYCSELPLISNSIMESDDICDSEPKFPPNDHLVNLYTRDLRKNANIEDSSTRSKQSESEQNRSSLLMEKQDSKETDGNNNSINDDDNNNENNKNEFNEAGPSSLNSLSAPDLTQNIQSRVVAPSRSSILAKSDIFYHYSRDIKLWTELQDLTVYYTKTAHKMFLKENRLNFTKYFDLISDSIVFTQLGCRLMQHEIKAKSCSKEIKKIFKGLISSLSRISINSHLYFDSAFHRKKMDTMNDKDNDNQENNCSRTEGDDGKIEVDSVHDLVSVPLSGKRNVSTSTTDTLTPMRSSFSTVNENDMENFSVLGPRNSVNSVVTPRTSIQNSTLEDFSPSNKNFKSAKSIYEMVDVEFSKFLRHVQLLYFVLQSSVFSDDNTLPQLLPRFFKGSFSGGSWTNPFSTFITDEFGNATKNKAVTSNEVTASSSKNSSISRIPPKMADAIASASGYSANSETNSQIDLKASSAASGSVFTPFNRPSHNRTFSRARVSKRKKKYPLTVDTLNTMKKKSSQIFEKLNNATGEHLKIISKPKSRIRNLEINSSTYEQINQNVLLLEILENLDLSIFINLKNLIKTPSILLDLESEEFLVHAMSSVSSVLTEFFDIKQAFHDIVIRLIMTTQQTTLDDPYLFSSMRSNFPVGHHEPFKNISNTPLVKGPFHKKNEQLALSLFHVLVSQDVEFNNLEFLNNSDDFKDACEKYVEISNLACIIVDQLIEERENLLNYAARMMKNNLTAELLKGEQEKWFDIYSEDYSDDDSENDEAIIDDELGSEDYIERKAANIEKNLPWFLTSDYETSLVYDSRGKIRGGTKEALIEHLTSHELVDAAFNVTMLITFRSILTTREFFYALIYRYNLYPPEGLSYDDYNIWIEKKSNPIKCRVVNIMRTFLTQYWTRNYYEPGIPLILN--------------------------------------------FAKMVVSEKIPGAEDLLQKINEKLINENEKEPVDPKQQDSVSAVVQTTKRDNKSPIHMSSSSLPSSASSAFFRLKKLKLLDIDPYTYATQLTVLEHDLYLRITMFECLDRAWG----------------------TKYCNMGGSPNITKFIANANTLTNFVS--------------------------------------HTIVKQADVKTRSKLTQYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKKTWDLVSTESKDLLKNLNN-------------------------LMDSKRNFVKYRELLRSVTDVACVPFFGVYLSDLTFTFVGNPDFLHNSTNIINFSKRTKIANIVEEIISFKRFHYKLKRLDDIQTVIEASLENVPHIEKQYQLSLQVEPRSGNTKG---------------STHASSASGTKTAKFLSEFTDDKNGNFLKLGKKKPPSRLFR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . : . . :. * * : : .: . : . . . :*: .: . * . : : :.: .* . . .:. :: . : : : : :. : *:..: : :. * . . : .: : :: : :: : .. ..: ::: : . :** :.: . .* : : : * :. * . : *. : : . : * : : . . ::. :* .. * : .: : . .:: : : : . :: :. . .:. :. : . : :. . *.: :* : . : . .* . .:. : .: : . :. . .:: . .. : .. . : :: : . * : *: : . :. :* . * : : : . * .:: :: ::: : : . : . *. : ... . :. *: *. . . . .. . :. *::: :. .: . :: *: .: ** .: : ::: :.: :: :. . . * **. .: ::.: . : :: :. : ** . : *::::: . : :: : .:.. : : . .* : ::.: :* : : .:.: : . : :. . ::. .: :.* : : :*:* : :.. .. **:. . :.:.: :: . * . : :: . * * .: . :: ::* *: * : * : .**: . *: . . : . * . : . * . .. . : : . :* . . : .* : . . .:: . . . : : . . : . . *:. : . .*. . . . . ", "identical_positions": 60, "similar_positions": 381, "identity": "3.4%" }, { "cls_id": "homologset.agr.FB:FBgn0001970", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6V1-1", "uniprot_id": "GLT11_RAT", "id": "Q6P6V1-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 11", "aln": "---MGSVTIRYFCYGCLFTSATWTVLLFIYFNFS-EVTQPLRNVPIKGSGPHGPFPKKFYPRFTRGPGRVLEPQFKANRMDDLMNNNIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAECRGK--SYPTDLPTASVVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELD-EYIQRYLPAKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSDLGGADSATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSFGNISERVELRKKLGCQSFKWYLDNVYPEMQVSGPKARLQQ--PVFINRGPKRPRVLLRGRLYHLQTNKCLVAQGRSSQ---KGGLVLLKACDYGDPTQVWIYNEEHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGK--NNRLYQVSVGQCLRVVDQMDQKGYVGMAICDGSSSQ--QWRLEG---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921L8-1", "uniprot_id": "GLT11_MOUSE", "id": "Q921L8-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 11", "aln": "---MGSITVRYFCYGCLFTSATWTVLLFIYFNFS-EVTQPLRNVPIKGSGPHGPFPKKFYPRFTRGPGRVLDPQFKANRIDRLMNNHIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAECRRK--SYPTDLPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELD-EYIQRYLPAKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSELGGPDGATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFILPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKNKSFGNISERVELRKKLGCQSFKWYLDNIYPEMQIPGPNAKPQQ--PVLINRGPKRPRVLQRGRLYHLQTNKCLVAQGRSSQ---KGGLVLLKTCDYGDPTQVWIYNEDHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGK--NNRLYQVSVGQCLRVMDLMDQKGYVGMAICDGSSSQ--QWRLEG---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCW6-1", "uniprot_id": "GLT11_HUMAN", "id": "Q8NCW6-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 11", "aln": "---MGSVTVRYFCYGCLFTSATWTVLLFVYFNFS-EVTQPLKNVPVKGSGPHGPSPKKFYPRFTRGPSRVLEPQFKANKIDDVIDSRVEDPEEGHLKFSSELGMIFNERDQELRDLGYQKHAFNMLISDRLGYHRDVPDTRNAACKEK--FYPPDLPAASVVICFYNEAFSALLRTVHSVIDRTPAHLLHEIILVDDDSDFDDLKGELD-EYVQKYLPGKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAAIREDRHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPLSELGRAEGATAPIKSPTMAGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSYGNISERVELRKKLGCKSFKWYLDNVYPEMQISGSHAKPQQ--PIFVNRGPKRPKVLQRGRLYHLQTNKCLVAQGRPSQ---KGGLVVLKACDYSDPNQIWIYNEEHELVLNSLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGK--NNRLYQVSVGQCLRAVDPLGQKGSVAMAICDGSSSQ--QWHLEG---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7M5-1", "uniprot_id": "F1R7M5_DANRE", "id": "F1R7M5-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---MGSVTLRYFCYGCLFTSVTWSILLFLYFNLSQESRLSFRNVPVQG-------QHRFQPRFTRGP--------AVQHRDGSQVRKGQALEAVKPDLSPELGMIFNKQDQEVRDMGYHKHAFNVLISNRLGYHRDVPDTRTDKCRDR--AYSVSLPTASIVICFFNEAFSALLRTVHSVLDRTPNYLLHEIILVDDHSELDDLKEDLD-SYVQQHLQKKVKVVRNEKREGLIRGRMIGASHATGEVLVFLDSHCEVNEAWLQPLLTPIKENRKTVVCPVIDIISADTLVYTPSPIVRGGFNWGLHFKWDPVPMSELNSPDGA---IRSPTMAGGLFAMDRNYFYELGQYDRGMDIWGGENLEISFRIWMCGGQLLIVPCSRVGHIFRKRRPYGSPGGQDTMAHNSLRLAHVWMDDYKEQYFALRPELRNRDYGDISERVSIRKRLQCHSFKWYLDNIYPEMQVSSP-HKPQQ--PVFINKGLKRPKVLQRGRLRNLLADKCLVAQGRPSQ---KGGAVVVKDCDPQDPEQEWAYDEEHELVLAGLLCLDMSEIRSSDPPRLMKCHGSGGSQQWTLGK--KNWLYQVSVGQCLAVGDPLSIKGYVSMAICDDSRSQ--QWQLEG---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7Z4T8-1", "uniprot_id": "GLTL5_HUMAN", "id": "Q7Z4T8-1", "name": "Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5", "aln": "---MRNAIIQGLFYGSLTFG-IWTALLFIYLHHNHVSSWQKK-------------SQEPLSAWSPGKK---VHQQIIYGSEQIPKPHVIVKRTDEDKAKSMLGTDFNHTNPELHKE-LLKYGFNVIISRSLGIEREVPDTRSKMCLQK--HYPARLPTASIVICFYNEECNALFQTMSSVTNLTPHYFLEEIILVDDMSKVDDLKEKLD-YHLETFR-GKVKIIRNKKREGLIRARLIGASHASGDVLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVIDDRTLEYKPSPLVRGTFDWNLQFKWDNVFSYEMDGPEGSTKPIRSPAMSGGIFAIRRHYFNEIGQYDKDMDFWGRENLELSLRIWMCGGQLFIIPCSRVGHISKKQTGKPS-TIISAMTHNYLRLVHVWLDEYKEQFFLRKPGLKYVTYGNIRERVELRKRLGCKSFQWYLDNVFPELEASVNSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D4M9-1", "uniprot_id": "GLTL5_MOUSE", "id": "Q9D4M9-1", "name": "Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5", "aln": "---MKSVIIQGLFCGFLAIG-LWASMLLLFLHLEQEDMLENE-------------KEELLKKRSLGKN---AHQQTRH-SEDVTH------------------DEVNFSDPELIQG-LRRYGLNAIMSRRLGIEREVPDSRDKICQQK--HYPFNLPTASIIICFYNEEFNTLLRAVSSVVNLSPQHLLEEIILVDDMSEFDDLKDKLD-YYLEIFR-GKVKLIRNKKREGLIRSKMIGASRASGDILVFLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPIVRGAFDWNLNLRWDNVFAYELDGPEGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGGQLFILPCSRVGYNSKALSQHRR-ANQSALSRNLLRVVHVWLDEYKGNFFLQRPSLTYVSCGNISERVELRKRLGCKSFQWYLDNIFPELEPFNTERKRKK--NRF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8MVS5-1", "uniprot_id": "GLT35_DROME", "id": "Q8MVS5-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 35A", "aln": "MMQIKRLLCKSCGLGTLLVAVVWLLALLFYSHSLRSSIRSAGWRID---------EGNATPRAELSYQARVTVGCTPNASITTGESPAAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEASG---DAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTG-ALISLDLCSKSNGAGGSWDIVQLKKPTEAEGRAKEARNSDKAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * . * *:.: : . . * : : . ::.:* ::* :* * :**:* * : . ** **:::**:** :*:::: :* : :* ::*.******* *.. :*: .*. ::: ::* :******.::*** .* *::******* *** **:*** * .: :. *:**:*. *: * .:*:*** *:*.*:::*: : : .:. ::**:*:**:**: *:** .:*:** **: * **:*:*:* * *** : *:******: : .:: :* **:.***:*:** :: . *:* :*:.:*::* *:.* ***.*::**:. ", "identical_positions": 131, "similar_positions": 122, "identity": "20.31%" }, { "cls_id": "homologset.agr.FB:FBgn0001977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XID1-1", "uniprot_id": "CPIN1_RAT", "id": "Q5XID1-1", "name": "Anamorsin", "aln": "MAEFGISPGQLVAVFCDKSSSEEALKKLVGRVQGLTGSEGQVFVENITQLLQSAHKESSFDVILSGIVPGSTSLHSPEALADMARILRPGGCLFLKEPVETTGVNNDKIKTASKLCSALTLSGLVEIKELQREALSPEEAQSMQEHLGYHSDSLLSVHVTGKKPNFEVGSSSQLKL-LHKKSS-SVKPVVDPATAKLWTLSANDMEDDSMDLIDSD--------------ELLDPEDLKKPDPAS---LKAPSCGEG--KKRKACKNCTCGLAEELEKEQSKAQ---------------------SSQPKSACGNCYLGDAFRCANCPYLGMPAFKPGEQVLLSSSNLQDA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WTY4-1", "uniprot_id": "CPIN1_MOUSE", "id": "Q8WTY4-1", "name": "Anamorsin", "aln": "MEEFGISPGQLVAVFWDKSSPEEALKKLVARLQELTGSEGQVFMENVTQLLQSSHKESSFDVILSGVVPGSTSLHSAEVLAEMARILRPGGCLFLKEPVETAEVNNDKMKTASKLCSALTLSGLVEIKELQREALSPEEVQSVQEHLGYHSDSLRSVRVTGKKPNFEVGSSSQLKL-PNKKSS-SVKPVVDPAAAKLWTLSANDMEDDSVDLIDSD--------------ELLDPEDLKRPDPAS---LKAPSCGEG--KKRKACKNCTCGLAEELEREQSKAQ---------------------SSQPKSACGNCYLGDAFRCANCPYLGMPAFKPGEQVLLSNSNLQDA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FI81-1", "uniprot_id": "CPIN1_HUMAN", "id": "Q6FI81-1", "name": "Anamorsin", "aln": "MADFGISAGQFVAVVWDKSSPVEALKGLVDKLQALTGNEGRVSVENIKQLLQSAHKESSFDIILSGLVPGSTTLHSAEILAEIARILRPGGCLFLKEPVETAVDNNSKVKTASKLCSALTLSGLVEVKELQREPLTPEEVQSVREHLGHESDNLLFVQITGKKPNFEVGSSRQLKLSITKKSSPSVKPAVDPAAAKLWTLSANDMEDDSMDLIDSD--------------ELLDPEDLKKPDPAS---LRAASCGEG--KKRKACKNCTCGLAEELEKEKSREQM--------------------SSQPKSACGNCYLGDAFRCASCPYLGMPAFKPGEKVLLSDSNLHDA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZB3-1", "uniprot_id": "CPIN1_DANRE", "id": "Q6AZB3-1", "name": "Anamorsin", "aln": "MADLGLQKGKRVLLIWTQPSSSSALKQFAESIAAVVGDQSLVSLENSERLLLSSHNASSYDCVLSGLLTDSSLIHSSEMLVEMARVMKPGGTLVLEEPVTGSEDTG--VRTAEKLMSAIKLAGLVSVTEVKTEPLSPKAAAALTERTGFSGNTLSRVRMTASKPDFEVGSSTQLKLSFGKKKTTTVKPALDPGTAQKWTLSANDMDDDDVDLVDSD--------------ALLDADDLKKPDPSS---LKA-SCGDDSKKKKKACKNCTCGLAEELEQESKAAQK--------------------ASQPKSACGNCYLGDAFRCGSCPYLGMPAFKPGEKVLLANTDIADK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3Y2-1", "uniprot_id": "DRE2_DROME", "id": "Q9V3Y2-1", "name": "Anamorsin homolog", "aln": "MENF--KGLQKSLYIWTDS---ADLDKRVEQLKAATG--GDVALENVHRLSFSSYANSSFDLIVI------ECAQLTDSYVKLLHMLKPSGKLHLVSYIG----------PAASLLQEIKLSGFINCREDSPDALTAE------------------------KPGYETGSS--ARLSFAKKNA---------SAVNVWKISGDDEE-----LIDEE--------------ELLDEEDKQKPDPAG---LRVCSTTGK----RKACKNCSCGLAEELETEKQSQKA--------------------TENAKSSCGNCYLGDAFRCSTCPYLGMPAFKPGEKVQLADNLLKSDI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36152-1", "uniprot_id": "DRE2_YEAST", "id": "P36152-1", "name": "Fe-S cluster assembly protein DRE2", "aln": "MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTP--EAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEENEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDS--ISDDL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . . : * : . .: . : . : ::*.* * . : . . . : .*. : : :. : :..: : : : : : ...: :: :: * :. : : :****:*:**: *: * * . : : ..**.* *******. *****:******: : * . : . ", "identical_positions": 39, "similar_positions": 69, "identity": "11.08%" }, { "cls_id": "homologset.agr.FB:FBgn0001978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE50-1", "uniprot_id": "D4AE50_RAT", "id": "D4AE50-1", "name": "Transcriptional repressor NF-X1", "aln": "----MAEAPPVSGTFKFNTDAAEFIPQERKNSGLNCGTQRRLDSNR--------IGRRNYSSSPPCHLPRHIPYDDVSAVHQHGYA-SGSKP---KSPQGFFQSS--NKSLKNHGLQNQPWQKLRNEKHQNRIKKAQGLTEQTSDTSSLESVARSESGTNPREHSPSESEK---------------EVVIADPRGAKPKKATQLTYNYGRGPKAKGRLRSEWGNRMSPKSED---ENARPVAISHS---DSSEASCRKPVVDPCVCRRSEQRRYPQKRPPWEVEGARPRPGRNPPKQESQRHINAGPKNNMPPLPKDNLRERPTKSACDTGNLAVVTKSSRRVDQEKNAGRRQDPQVLSPFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWARSPASHADGQSGWRCPACQNVSAHVPSTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCP-PCPAFTTKTCECGRTRHTVRCGQPVSVHCSNVCENILNCGQHRCAELCHAGQCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQPCPRLPHLVRYCPCGQTPLSQLLEHGSNGRKTCMDPVPSCGKVCGKPLS----CGSSDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVD--KEHKCPLICGRKLRCGLHRCEEPCH-RGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARIHECDHPVYHSCHSEEKCPPCTFLTQKWCMGK---HELRSNIPCHLVDISCGLPCSAMLPCGMHKCQRLCHKGECLVD-EACKQPCTTPRADCGHPCMAPCHPSLPCPVTACKAKVELQCECGRRKEMVICSEASGTYQRIAAISMASKITDMQLGDSVEISKFITKKEVQQARLQCDEECAALERKKRLAEAFDITDDSDPFNVRSSASKFSDSLKDDARKDFKFVSDIEKEMEALVEAVNKGKSNKKSYCFPPMNRDHRRIIHDLAQVYGLESVSYDSEPKRNVVVTAIRGKSICPPTTLTSVIERETQTRPPPPIPHHRHQADKNPGSSNLQKIVKEPVIDYFDVQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AY10-1", "uniprot_id": "NFX1_MOUSE", "id": "B1AY10-1", "name": "Transcriptional repressor NF-X1", "aln": "----MAEAPPVSGTFKFNTDAAEFIPQERKTSGLNCGTQRRLDSSR--------IGRRNYSSSPPCHLPRHIPYEDISAVHQHSYA-SGSKP---KSPQGFFQSS--NKSLKNHGLQNQPWQKARNEKHQNRNKKAQGLSEQTSDTSSLESVARSESGTNPREHSPSESEK---------------EVVIADPRGAKPKKAAQLTYNYGRGPKAKGRLRSEWGNRMSPKSED---ENTRPVAISHT---DSSDASCRKPVVDPCVCRRNEQRRYPQKRPPWEVEGARPRPGRNPPKQESQRHINAGPKTNMSPIPKDNLRERPTKSACDTGNLAVVSKSSRRVNQEKTAVRRQDPQVLSPFPRGKQNHMLKNVETHTGSLIEQLTTEKYECMVCCELVQVTAPVWSCQSCFHVFHLNCIKKWARSPASHADGQSGWRCPACQNVSAHVPNTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCP-PCPAFTTKTCECGRTRHTVRCGQPVSVHCSNACENILNCGQHHCAELCHGGQCQPCRIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGSHTCSQVCHPQPCQPCPRLPHLVRYCPCGQTPLSQLLEHGSNARKTCMDPVPSCGKVCGKPLA----CGSSDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVD--KEHKCPLICGRKLRCGLHRCEEPCH-RGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARIHECDHPVYHSCHSEEKCPPCTFLTQKWCMGK---HELRSNIPCHLVDISCGLPCSAMLPCGMHKCQRLCHKGECLVD-EACKQPCTTPRGDCGHPCMAPCHPSLPCPVTACKAKVELQCECGRRKEMVICSEASGTYQRIVAISMASKITDMQLGDSVEISKLITKKEVQQARLQCDEECAALERRKRLAEAFDITDDSDPFNVRSSASKFSDSLKDDARKDLKFVSDVEKEMETLVEAVNKGKNNKKSHCFPPMNRDHRRIIHDLAQVYGLESISYDSEPKRNVVVTAVRGKSVCPPTTLTSVIERETQTRPPPPIPHHRHQADKAPGSSTLQKIVKEAVIDYFDVQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12986-1", "uniprot_id": "NFX1_HUMAN", "id": "Q12986-1", "name": "Transcriptional repressor NF-X1", "aln": "----MAEAPPVSGTFKFNTDAAEFIPQEKKNSGLNCGTQRRLDSNR--------IGRRNYSSPPPCHLSRQVPYDEISAVHQHSYHPSGSKP---KSQQTSFQSSPCNKSPKSHGLQNQPWQKLRNEKHHIRVKKAQSLAEQTSDTAGLESSTRSESGTDLREHSPSESEK---------------EVVGADPRGAKPKKATQFVYSYGRGPKVKGKLKCEWSNRTTPKPEDAGPESTKPVGVFHP---DSSEASSRKGVLDGYGARRNEQRRYPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPIPKDDLNERPAKSTCDSENLAVINKSSRRVDQEKCTVRRQDPQVVSPFSRGKQNHVLKNVETHTGSLIEQLTTEKYECMVCCELVRVTAPVWSCQSCYHVFHLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPNTYTCFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCP-PCPAFMTKTCECGRTRHTVRCGQAVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDVLCGTDVGKSDGFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTPLSQLLELGSSSRKTCMDPVPSCGKVCGKPLP----CGSLDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVD--KEHKCPLICGRKLRCGLHRCEEPCH-RGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARVHECDHPVYHSCHSEEKCPPCTFLTQKWCMGK---HEFRSNIPCHLVDISCGLPCSATLPCGMHKCQRLCHKGECLVD-EPCKQPCTTPRADCGHPCMAPCHTSSPCPVTACKAKVELQCECGRRKEMVICSEASSTYQRIAAISMASKITDMQLGGSVEISKLITKKEVHQARLECDEECSALERKKRLAEAFHISEDSDPFNIRSSGSKFSDSLKEDARKDLKFVSDVEKEMETLVEAVNKGKNSKKSHSFPPMNRDHRRIIHDLAQVYGLESVSYDSEPKRNVVVTAIRGKSVCPPTTLTGVLEREMQARPPPPIPHHRHQSDKNPGSSNLQKITKEPIIDYFDVQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40798-1", "uniprot_id": "STC_DROME", "id": "P40798-1", "name": "Protein shuttle craft", "aln": "MAEYWQQLTNGAGEAGPGNESSAMADCNGGHESAAVGGSCNRHSNNNYVNFNQFIMQHNLGGGAPSNATSTMQHPVGSSYTNFSLGGGGGAFGLNPPVASASTSHFANVSHQSPNFYSQAMIPTYQNGDGIARVTVTSSYGSVNPSNSNFSSFYTPFGNNPFDFSASKLQASAPEFVPNFAKLSLEETPAAATTNGNSTASLETAINETRPRTLRAQEPAERGANNQCSNHNYERERERERDRDRDRERDRDRDRDRDRDRDRDRDRDSRPGNTRQQRRSDYRDDREDRYERSDRRRPQKQQRYDNHRSNKRRDDWNRNRDRINGFPRAVDDLDTSNESAHPSPEKQSQLQQISPRRGPPLPPADNEKLSQ-----REKLVRDIEQRRLECLVCVEAIKSHQPTWSCRNCYHMLHLKCTITWASS----SKSEVGWRCPACQNVLQDLPRDYLCFCGKLKNPPVSRTELAHSCGEVCCRIEG---CSHACTLLCHPGPCP-PCQANVVRSCGCGRSTKTMQCAMKEEVLCGEICDKLLNCGEHRCQAECHSGKCAACSEQVVQQCHCGKQERKVPCTRESQDKR---TYSCKDSCGQPLPCGHHKCKDSCHAGSCRPCKLSPEQITSCPCGKMPVP------AGQRSSCLDPIPTCEGICSRTLR----CGKPAHPHQCGSKCHLGQCPPCPKQTGVKCRCGHMDQMIKCRQLCNRADDARCKRRCTKKRSCGKHKCNVECCID--IDHDCPLPCNRTLSCGKHKCDQPCH-RGNCPPCYRSSFEELYCECGAEVIYPPVPCGTKKPICKLPCSRIHPCDHPPQHNCHSGPTCPPCMIFTTKLCHGN---HELRKTIPCSQPNFSCGMACGKPLPCGGHKCIKPCHEGPCQSAGEICRQSCTKPRPTCGHKCAAACHEG-ACPETPCKELVEVQCECGNRKQNRSCQELAREHSRIATIQLASSMAEMSRGNYMELSEILAPAKKSNKTLDCNDECRLLERNRRLAAALSSGNSD---TKQKCLTKYSEFVRGFAKKNPALTKSVYETLTDLVKLAKESKQRSRSHSFPTMNREKRQLVHELCEVFGIESVSYDKEPNRNVVATAHKDRCWFPATSIMEVLARESGQRRVPVPSNNAWGLKK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53971-1", "uniprot_id": "FAP1_YEAST", "id": "P53971-1", "name": "FKBP12-associated protein 1", "aln": "-----------------------------MTEHESLGLEQNQDGGD------------------------TYRHHNLSDGCISSVEDANEQP-----------SSYEEESDDDMQYYERAIQEISSGDSYVCMICTVEMDYTCQMFACKRCYRVFDYG-CIREWALKSTEK-----------------------TVDRIWKCPNCYYVSKRVPVKNRPTCWCGKVVNPDPNP----------LDPN----SCGQTCNASTCMHGCSKICHLGPHPECTRMVEIMCHCGKHSKSIFCYQSKVMKKNFNCQEVCGLPLS-CSIHTCKKKCHPGLCGPCPEMIISKDSPKKQIKCYCGNHTRANIKCSETKFPK-----SGKSSKDENGNRWIGVFACADNRVVD--YSCR--KHSFIESCISPPTIN--------GEKACPFLPSSLKTCPCGRTALEELTK-PRKHCDDPIPTCDSRCG--KPLKCGKHSCPFTCHDKACMEPCLQIDSVKCACEQSTFSVPCGFQGRPRCNIKCESLMSCRRHRCTDRCCSGRPSAIRRKKNLFRTQDLLDESLVEAK----------HICLKPCNLTLSCGIHKCQRKCHPGKCPPCLESDSNDLVCPCGNTVVP--------APVRCGTKLPTCNHPCIKVVRGESTCGHKPMPHTCHSLDVS--CPPCTETVFKPCKCGKKTKVR----TVCFQTDVSCGIKCGIPLSYCYHTCQKTCHLPGNCQKVCKQTCGQKRLNCNHECPKPCHGKTECPDLPCATLVKIYCKCGR--IKKSVTCGAKSDRVSVTESSVLDCNEECEALKRLKELKEAFGIKEETNNFTSNELDALKKLVSVATTFEELQLPFTEAALSVYSKQERWCSQIEAILN-------KLMDDKTRSSLHFKPMRPPQRHFIRELAKAYGLYSESQDREPMRSVFIKKEDNG-------ASNKPVLSLAEAYPLYESFKQLQKERKAQEFQARTTAKLIN---------------FEVQDTEPKVEVAKKNGFLVQNLVAGNTAEDLRRFFEPHLKHTLVVN-PQYLILDDGKTALVYPENYETASVNTERDMELLVGHFDFMAKEAFLADSISLCSTEEELERRLDTPVIQEDSPVMDNNT---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . ... : * . .. * : * .. .:. . . . . * : : .. : . : : : . . . . . : . : : :. : : . : : . : : . . .: :. : . .: .: :.. : :**: * : .* : . ** . * .: * * : :*.. * : *:* : ** .* ** .* * :: :: *. *. *:.::.* .*:* * .*: . . ...: . * . *. * ** *.*. **. * * ****: :. * :*:* * : : ** * * . * **.. *:*. : * :* *.*: * : :: * *.:. *.* :*** : :* ::: :: *.** * .*.**:: . . : : *:. : . : . . . ::. :. . :. . * : * : . . . : : .*. *: **. . :. . : : : : . : : . . :. .* . : : .. . : : :.: : . . : :: : ::: . . . * * . . : . :: . . * .. .: ", "identical_positions": 92, "similar_positions": 229, "identity": "7.9%" }, { "cls_id": "homologset.agr.FB:FBgn0001983", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY31-1", "uniprot_id": "SNAI3_MOUSE", "id": "Q9QY31-1", "name": "Zinc finger protein SNAI3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MPRSFLVKTHS-SHRVPNYGKLETLREANGSCSACKELAGSRHLPDEEAPCNPSDPLQPWDSTS------------------AVACISLPLLPNHRETLG-VSGPEPQETSWVGPRAAQAPSVTLKDSFTLPPLLVLPTRWPPILGPDGALNEHLRAEG---------------------------------TSRVPGSFECIHCHRPYHTLAGLARHQQLHCHLPTG----RAFTCRYCDKEYASLGALKMHIRTHTLPCICKVCGKAFSRPWLLQGHIRTHTGEKPYTCSHCSRAFADRSNLRAHLQTHVGTKKYRCAVCPKAFSRMSLLARHEEAGCCPGP-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LCD7-1", "uniprot_id": "A0ABK0LCD7_RAT", "id": "A0ABK0LCD7-1", "name": "", "aln": "----------------MTPATVPCNREHERQGQVDG--------QAPAGSVRDHDAGQPSPVGQTPPTTRRVPGPRTCPGRGFAAPPRRAPRWLAEVVRYANEPDPSRTCRLRCPRAPPDATLGVPP------QALDSACSREGTMPRSFLVKTHS-SHRVPNYGKLETLREANGSCSACEELVGSCHLPDKEASSNPSDPLQPWDSTS------------------AIACVSLPLLPHHGETLG-TSGPEPQETSLVGPRAGQAPSVTLKDSFNLPPVLVLPTRWPPILGSDGALDEHLRAEG---------------------------------TSRVPGSFECIHCHRPYQTLAGLARHQQLHCHLPTG----CAFTCRYCDKEYASLGALKMHIRTHTLPCVCKVCGKAFSRPWLLQGHIRTHTGEKPYTCSHCSRAFADRSNLRAHLQTHAGTKKYSSACLLDLFQKGASIGK---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43623-1", "uniprot_id": "SNAI2_HUMAN", "id": "O43623-1", "name": "Zinc finger protein SNAI2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MPRSFLVKKHFNASKKPNYSELDTHTVIISPY-LYESYSMPVIPQPEILSSGAYSPITVWTTAAPFH---------------AQLPNGLSPLSGYSSSLGRVSPPPPSDTSSKDHSGSES----------------------PISDEEERLQSKLSDP----------------------------------HAIEAEKFQCNLCNKTYSTFSGLAKHKQLHCDAQSR----KSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCVAH-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJP2-1", "uniprot_id": "Q9VJP2_DROME", "id": "Q9VJP2-1", "name": "", "aln": "MDKLKYSRCPLKKRPIMVEESSPEDHLSHDEGPVDLSVASAAVPMEPHWMAKSEPEPQPVPTELRRRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEEEVMEPEPEPEQHLPLRYTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEYEDCMKMQNIKEEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGGPSGSGGGFDQQQLQQHLQVYEEGHNPHQLYYAGSVGSSNGEEEEGGEYQMQPPAIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . . : * . *.: . : . *: : * .:. . .: . ..: : . : . :.* * :.* * :**::*:*:** *:*: *** *.**************** * :***********************::* **.************:*** ..*** . . *.: : : : ", "identical_positions": 82, "similar_positions": 55, "identity": "14.96%" }, { "cls_id": "homologset.agr.FB:FBgn0001986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXU0-1", "uniprot_id": "A0A8I5ZXU0_RAT", "id": "A0A8I5ZXU0-1", "name": "Exosome RNA helicase MTR4", "aln": "-----MADAFGDELFSVF-------EDDSTTAAGTKKDKEKEKDKWKGPPGPADKAGKRLDTRLQSEPASSGKNKRDLDVEGTDEPIFGKKPRIEDSINEDLSLADLMPRVKVQSVETVEGCTHEVALPADEDYIPLKPRVGK-AAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAG--DLAKGDQKGRKG----GTKGP----SNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDD-FGWGVVVNFSKKSNVKPNSGELDP--LYVVEVLLRCS--------KESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEDHMTHPPIDQLLSAVSHCVWRSRENQELILSYYMGSGAETQALRLGSRHLYPLGHLAGPQHVFLTTGEVGESCTSEQGVSSRES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU3-1", "uniprot_id": "MTREX_MOUSE", "id": "Q9CZU3-1", "name": "Exosome RNA helicase MTR4", "aln": "-----MADAFGDELFSVF-------EDDSTSAAGAKKDKEKEK--WKGPPGSADKAGKRLDTKLQSESASGGKNKRDLDVEGTDEPIFGKKPRIEDSINEDLSLADLMPRVKVQSVETVEGCTHEVALPADEDYIPLKPRVGK-AAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAG--DLAKGDQKGRKG----GTKGP----SNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDD-FGWGVVVNFSKKSNVKPNSGELDP--LYVVEVLLRCS--------KESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQSVLKSIQEVQRRFPDGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCERKAQIALDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEG-----------------ITKIKRDIVFAASLYL--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42285-1", "uniprot_id": "MTREX_HUMAN", "id": "P42285-1", "name": "Exosome RNA helicase MTR4", "aln": "-----MADAFGDELFSVF-------EGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGK-AAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAG--DLAKGDQKGRKG----GTKGP----SNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDD-FGWGVVVNFSKKSNVKPNSGELDP--LYVVEVLLRCS--------KESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEG-----------------ITKIKRDIVFAASLYL--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y134-1", "uniprot_id": "Q9Y134_DROME", "id": "Q9Y134-1", "name": "RNA helicase", "aln": "MDIEELFDCFDEVTPSVPPPALNQEEKPSGSSASKKGNKRQADGTTASKEATSSKGAEGDDKGDVTEEPTKRLKQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTRIVTHLLDAPKSCTHEVAAHPDQEYIPLKPFSGV-PAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAGKTVVAEYAIAKSLAAKQRVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTEILRNMLYRGSEIMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAG--EAGKGDQKGRHG----GIKGTNAGQTNIFKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDVLTEEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGRDIVQGKADPINSAFHLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLTIKDEHNIASYHHIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAGSQE-YDWGIVLNFKKQDQSRKNPLKAEP--SVTIDVLLHVS--------EAAAKTGDTEPCK---PNERGCMEVVPVAHTLITQISSIRVYFPNDLRSADNRRAVLKTIQEAKKRFPLGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHRRYQDKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSADELLMTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVSTECKLDLDADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASKTIGNTDLENKFSEG-----------------IRLLKRDIVFAASLYL--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47047-1", "uniprot_id": "MTR4_YEAST", "id": "P47047-1", "name": "ATP-dependent RNA helicase DOB1", "aln": "MDSTDLFDVFEETPVELPTDS--NGEKNADTNVGDTPDHTQDKKHGLEEEKEEHEENNSENKKIKSNKSKTEDKNKKVVVPVLADS-FEQEASREVDASKGLTNSETLQVEQDGKVRLSHQVRHQVALPPNYDYTPIAEHKRVNEARTYPFTLDPFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQRVIYTSPIKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEILRSMLYRGSEVMREVAWVIFDEVHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKMEPQVAKGMVKGQADRLDSAFHLGYNMILNLMRVEGISPEFMLEHSFFQFQNVISVPVMEKKLAELKKDFDGIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFLQPGRLVEISVNGKDNYGWGAVVDFAKRINKRNPSAVYTDHESYIVNVVVNTMYIDSPVNLLKPFNPTLPEGIRPAEEGEKSICAVIPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFPDGIPVLDPVKNMKIEDEDFLKLMKKIDVLNTKLSSNPLTNSMRLEELYGKYSRKHDLHEDMKQLKRKISESQAVIQLDDLRRRKRVLRRLGFCTPNDIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERCKEAPRLKPELAEPLKAMREIAAKIAKIMKDSKIEVVEKDYVESFRHELMEVVYEWCRGATFTQICKMTDVYEGSLIRMFKRLEELVKELVDVANTIGNSSLKEKMEAV-----------------LKLIHRDIVSAGSLYL--------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * : .: * : : .. . :: : . : : : :: .. ::. . : .:. . .. : : . *:** .: :* *: *: *** **.** ** *:*..:************** ****** :* *****:*:*********:**: ** ****:***:**** *.**:*******.*******:****.**:***:*****.*********:*****:*:*********** :****:*::*.****::**::********:*** ***::*:***:. *:*:** .** : : : . *.:*::* * .. :::****** :::: ***:*****:*** *::*:*****: :**: : ::*.**: *.: *:.***::::****:*******.********.***** **::*.*******::*:****:**:** **:**:.***:*.******:*******:**:****:*:***:.* :.: :::*.** ::***** ***:***:*** *.**:***:**:***: ::* : .:: : : : : : :*..: *:.*.. : ::..: : :* *.********:: ..: :.** *::* *: : : . ::*::. . : .* : .*:. *:*: :. *..:*:*:*:*:*. .::.:* *:::*.::*** * *:*:*:.:* *:*. : .:::.:. :: :: .:** :. .** :: . * : :::. * ::. :::::*:*:*: *******:*:....*:**:*******:**.****:**::*** **:*.. **.******. :*...* : :*: **: *:: * :***: :.*::: . *:..*: **:** *. *::* :*****::***:** ::*****:::: :.:::***:.*::*: : :.: * *: ", "identical_positions": 439, "similar_positions": 346, "identity": "38.41%" }, { "cls_id": "homologset.agr.FB:FBgn0001987", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62888-1", "uniprot_id": "NLGN2_RAT", "id": "Q62888-1", "name": "Neuroligin-2", "aln": "-----------------MWLLALCLVGLAGAQR----------------------------------------GGGGPGGGAPGGPGLGLGSLGEERFPVVN-----TAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARR------FQPPEAPASWPGVRNATTLPP---ACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSE--DCLYLNLYVPTEDGPLTKKRDEATLNP--PDTDIRDSGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVN---YQPLKYTRLLAAKVGCDREDSTEAVECLRR-KSSRELVDQDVQPARYHIAFGPVVDG------------------DVVPDDPEILMQQGEFLN-YDMLIGVNQGEGLKFVEDSAESE--DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCN-------FSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP---------NRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRAN--KVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRTPGPGTSGTRRPPPPATLPPE-SDIDLGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPTAGRELPPEEELVSLQLKRGG---GVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSG-LGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZK9-1", "uniprot_id": "NLGN2_MOUSE", "id": "Q69ZK9-1", "name": "Neuroligin-2", "aln": "-----------------MWLLALCLVGLAGAQR----------------------------------------GGGGPGGGAPGGPGLGLGSLGEERFPVVN-----TAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARR------FQPPEAPASWPGVRNATTLPP---ACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSE--DCLYLNLYVPTEDGPLTKKRDEATLNP--PDTDIRDSGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVN---YQPLKYTRLLAAKVGCDREDSTEAVECLRR-KSSRELVDQDVQPARYHIAFGPVVDG------------------DVVPDDPEILMQQGEFLN-YDMLIGVNQGEGLKFVEDSAESE--DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCN-------FSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP---------NRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRAN--KVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRTPGPGTSGTRRPPPPATLPPE-SDIDLGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPTAGRELPPEEELVSLQLKRGG---GVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSG-LGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFZ4-1", "uniprot_id": "NLGN2_HUMAN", "id": "Q8NFZ4-1", "name": "Neuroligin-2", "aln": "-----------------MWLLALCLVGLAGAQR----------------------------------------GGGGPGGGAPGGPGLGLGSLGEERFPVVN-----TAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARR------FQPPEAPASWPGVRNATTLPP---ACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSE--DCLYLNLYVPTEDGPLTKKRDEATLNP--PDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVN---YQPLKYTRLLAAKVGCDREDSAEAVECLRR-KPSRELVDQDVQPARYHIAFGPVVDG------------------DVVPDDPEILMQQGEFLN-YDMLIGVNQGEGLKFVEDSAESE--DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCN-------FSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP---------NRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRAN--KVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPP-AGAPGTRRPPPPATLPPE-PEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGG---GVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSG-LGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KT70-1", "uniprot_id": "Q7KT70_DROME", "id": "Q7KT70-1", "name": "", "aln": "MMHKLKYRDKLKWLLALLVLIGTCFIQTRGQTRDPRFYSRPGVDYHWPNPGDPDYRTYTFNDRRYGHYQPNGYGANYPGRNPPGQYPQGMPNEDRFRFDPNDPNARTQFPGVLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFR-YNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFM-DTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLVVICCIMWRNAKRQSDRFYDEDVFINGEGLEPEQDTRGVDNAHMVTNHHALRSRDNIYEYRDSPSTKTLASKAHTDTTSLRS-PSSLAMTQKSSSQASLKSGISLKETNGHLVKQSERAATPRSQQNGSTAKVASPPVEEKRLLQPLSSTPVTQLQAEPAKRVPTAASVSGSSRSTTPVPSARSTTTHTTTATLSSQPAAQPRRTHLVEGVPQTSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:. *:: * * *.. ** ..** *: . .. ** : * : * *.:*:.: : : :.*. * : :: *:. : : :.:. : .: ***. : : . .:. . :* . * *. : .* : ..* ** *.*. . * ***:::***.::.*:.*:*:* :**:: :*:*.*******.********: : ****:*** ****: :** .*.** : **:**.***.:...**::: ::..:.::.*****:*::.*:: *:. : :*:*. :**. *.* : *:*** :. ** : :..* :.:***:* .:.: ** *:: *:* . : : **. *. ** :. . . :.. ** .: :.* . *.*. . : : *:**::** *.* :*. : *. : :::* : **. .** : : ***:*.: :* . *:* . .*. * :: *.*:: *::** : ::.** :* ..* :****: *:*. . :* :: . ::. : ::...* : * . : : .. :* * *: . .: .: * .. . . * . : * : : ..*. *. :..:: . .: . : ** * . . *. . :: ..* :.: .* .* : *: : .*. .: : ::.* *.: *.* * * . * . : .: . :...* . .* * *.. ..: *. . .. *:* .:.. * . . * *", "identical_positions": 201, "similar_positions": 307, "identity": "20.96%" }, { "cls_id": "homologset.agr.FB:FBgn0001989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GCX1-1", "uniprot_id": "A0A8I6GCX1_RAT", "id": "A0A8I6GCX1-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6", "aln": "----------------MSGYTPDEKLRLQQL----RELRRRWLKDQELSP---REPVLPPRRMWPLERFWNNFLRDRA---------LWKYM-------------------------------TKPYAIVGTKPRIFPGDTILETGEVIPPMRDFPDKHH-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UIU2-1", "uniprot_id": "NDUB6_MOUSE", "id": "Q3UIU2-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6", "aln": "----------------MSGYTPDEKLRLQQL----RELRRRWLKDQELSP---REPVLPPRRMWPLERFWDNFLRDGA---------VWKNMVFKAYRSSLFAVSHVLIPMWFVHYYVKYHMATKPYTIVSSKPRIFPGDTILETGEVIPPMRDFPDQHH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95139-1", "uniprot_id": "NDUB6_HUMAN", "id": "O95139-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6", "aln": "----------------MTGYTPDEKLRLQQL----RELRRRWLKDQELSP---REPVLPPQKMGPMEKFWNKFLENKS---------PWRKMVHGVYKKSIFVFTHVLVPVWIIHYYMKYHVSEKPYGIVEKKSRIFPGDTILETGEVIPPMKEFPDQHH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3W2-1", "uniprot_id": "Q9V3W2_DROME", "id": "Q9V3W2-1", "name": "", "aln": "MVAGGASETGGVKPMVIAGRMVRERERLIGMSPEERAWRKQWLKDQELHHGPRKVPALELELNNPIKRFYRAPLDKVCNVLEPVLGFQRAYTVRFWTGKALLALTGIYAGAYYFKYNQNDWTRKGGWRVIHSRKQCVPGDEGYPKVSDRSAPSDYAARGFNESPLKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* *: ** : * *::******* : *.* . *:::*: * . . : :: .: : .*** . . .. ::. : . ", "identical_positions": 21, "similar_positions": 31, "identity": "12.57%" }, { "cls_id": "homologset.agr.FB:FBgn0001990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96I27-1", "uniprot_id": "ZN625_HUMAN", "id": "Q96I27-1", "name": "Zinc finger protein 625", "aln": "-----------------------MGER-------------LLESKKDHQHGEILTQVPDDMLKKKTPRVKSCGEVSVGHASLNRHHRADTGHKPYEYQEYGQKP---------------------YKCTYCKKAFSDLPYFRTHEWAHTG-------------------------------------GKPYDCEECG--------KSFISRSSIRRHRIMHSGDGP--------------------------------------------YKCNFCGKALMCLSLYLIHKR-THTGEKPYECKQCGKAFSHSGSLRIHERTHTGEKPYECSECGKAFHSSTCLHAHKITHTGEKPYECKQCGKAFVSFNSVRYHERTHTGEKPYECKQCGKAFRSASHLRTHGRTHTGEKPYECKQCGKAFGCASSVKIHERTHTGEKPCSSNTSKGQGEKIA------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJN5-1", "uniprot_id": "WEK_DROME", "id": "Q9VJN5-1", "name": "Zinc finger protein weckle", "aln": "MGVPTSDWIYWCRLCARDDVVYKVRERDDDLVRIISKCFDVEMTLEEPELGSMLCEECYSVIGQLITFSDSVSKVQAIFELLRHSEPQDSQDLDALRLEYGLPPACKQDLEFLDIDDTEDRCSLVEELTISDHSTSPSPDFEAQTVRTRANLKQCNSDPKVLASPTASIPEVETKRSRRQQFAAKRNSKVYTATESDDEEAILDEDEAVSPPPLKRKRGRPKGSGKQKNVDDSDNVTSREPDDNAKSKQDDKTSELSMSPHGSQSSNFVDYPCKICNETFMSFMALRRHKHDMHGGPKKYVCDHCGKGLKTFTSLVEHQLVHTEEKPCICPVCNAGFKNKARLRVHSQTH-GEPKFECNVCGKKLQTRAILNKHKYVHTDERRFKCEVCGSGCKNSTALKIHLLGHTGLRPYVCKYCGKAFASNTNCRSHKWKKHPELASKEDETESSRVPVPTLEELRAITREMAKAKQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** : : :: : *.:* : .:: : . .* .:*.. . *.: . *: . *** * : * ..:: * * *.:: . .* * . *.. .. :* ..::*:* .*.* * *::*.:::*.: **: * * * * *.:***.:. ** *: .** *** *. *. .*:..: *:.*. ** ** :**: *** : : :. *: .**.*: ::*: **.. :.:: *: * *** :** ** *****.. :. : *: .: * ....: ::.. :. ", "identical_positions": 83, "similar_positions": 114, "identity": "17.62%" }, { "cls_id": "homologset.agr.FB:FBgn0001991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99246-2", "uniprot_id": "CAC1D_MOUSE", "id": "Q99246-2", "name": "Voltage-dependent L-type calcium channel subunit alpha-1D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMMMMKKMQHQRQHQEDH------------ANEANYARGTRLPISGEGPTS-----------------------------------------------QPNSSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSL---SQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETE-----GGNHSS----GKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFF---ADSDIVAEEDPAPCAFS-GNGRQCTANG-TECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EEEGGEEGKRN----------------------------TSMPTSETESVNTENVSGEGETQG--CCGTLWCWWKRRGAAKTGPSGCRRWGQAISKSKL---------------------------------------SRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQ-TKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYQEDAEDKDPYPPCDVPVGEEE--------------EEEEEDEPEVP------AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFT--------------------AIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPK----------------------------GYFSDAWNTFDSLIVIGSIIDVALSEADPSESETIPLPTA----TPGNS------EESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPDSDYNPGEE--YTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQDYFRKFKKRKEQGLVG-KYPAKN-TTIALQAGLRTLHDIG-PEIRRAISCDLQDDEPEDSKPEEED-VFKRN--------GALLGNHVNHVNSD-RRDSLQQTNTTHRPLHVQRP-----SMPPASDTEKPLFPPAGNSG-----CHNHHNHNSIGKQAPTSTNANLNNANMSKAAHGKPPSIGNLEHVSENGHYS-CKHDRELQRRSSIKRTRYYETYIRSESGDEQFPTICREDPE------------------------IHGYFRDPRCLGEQEYFSSEECCEDDSSPTWSRQNYNYYNRYPGSSMDFERPRGYHHPQGF--LEDDDSPTGYDSRRSPRRRLLPPTPPSHRRSSFNFECLRRQSSQDDVLPSPALPHRAALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDW---SPCYTPLIQVDRSESMDQVN-------------GSLPSLHRSSWYTDEPDIS-----YRTFTPASLTVPSSFR-NKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGSVCPRANG-DMGPISHRQDYELQDFGPGYSDEEPDPG---REEEDLADEM---------------ICITTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27732-1", "uniprot_id": "CAC1D_RAT", "id": "P27732-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMMMMKKMQHQRQQQEDH------------ANEANYARGTRLPISGEGPTS-----------------------------------------------QPNSSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSL---SQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACISIVDWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIASGLLLHPNASVRNGWNLLDFVIVIVGLFSVILEQLTKETE-----GGNHSS----GKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFF---ADSDIVAEEDPAPCAFS-GNGRQCAANG-TECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EEEGGEEGKRN----------------------------TSMPTSETESVNTENVSGEGETQG--CCGSLWCWWKRRGAAKTGPSGCRRWGQAISKSKLRSHGAREALCVCRCSLESLVKLWTSRFSAHLQAAYVRPYSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQ-TKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLKLFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYQEEAEDKDPYPPCDVPVGEEE--------------EEEEEDEPEVP------AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFT--------------------AIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPK----------------------------GYFSDAWNTFDSLIVIGSIIDVALSEAD-------------------NS------EESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPDSDYNPGEE--YTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQDYFRKFKKRKEQGLVG-KYPAKN-TTIALQAGLRTLHDIG-PEIRRAISCDLQDDEPEDSKPEEED-VFKRN--------GALLGNYVNHVNSD-RRESLQQTNTTHRPLHVQRP-----SIPPASDTEKPLFPPAGNSV-----CHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGDLEHVSENGHYS-YKHDRELQRRSSIKRTRYYETYIRSESGDEQLPTIFREDPE------------------------IHGYFRDPRCFGEQEYFSSEECCEDDSSPTWSRQNYSYYNRYPGSSMDFERPRGYHHPQGF--LEDDDSPIGYDSRRSPRRRLLPPTPPSHRRSSFNFECLRRQNSQDDVLPSPALPHRAALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDW---TPCYTPLIQVDRSESMDQVN-------------GSLPSLHRSSWYTDEPDIS-----YRTFTPASLTVPSSFR-NKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGSVCPRANG-DMGPISHRQDYELQDFGPGYSDEEPDPG---REEEDLADEM---------------ICITTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01668-1", "uniprot_id": "CAC1D_HUMAN", "id": "Q01668-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMMMMKKMQHQRQQQADH------------ANEANYARGTRLPLSGEGPTS-----------------------------------------------QPNSSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSL---SQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETE-----GGNHSS----GKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFF---ADSDIVAEEDPAPCAFS-GNGRQCTANG-TECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EEEGGEEGKRN----------------------------TSMPTSETESVNTENVSGEGENRG--CCGSLC--------------------QAISKSKL---------------------------------------SRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQ-TKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEE--------------EEEEEDEPEVP------AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFT--------------------AIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPK----------------------------GYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTA----TPGNS------EESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEE--YTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQDYFRKFKKRKEQGLVG-KYPAKN-TTIALQAGLRTLHDIG-PEIRRAISCDLQDDEPEETKREEEDDVFKRN--------GALLGNHVNHVNSD-RRDSLQQTNTTHRPLHVQRP-----SIPPASDTEKPLFPPAGNSV-----CHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPE------------------------IHGYFRDPHCLGEQEYFSSEECYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGF--LEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDW---TPCYTPLIQVEQSEALDQVN-------------GSLPSLHRSSWYTDEPDIS-----YRTFTPASLTVPSSFR-NKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVRPRANG-DVGPLSHRQDYELQDFGPGYSDEEPDPG---RDEEDLADEM---------------ICITTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUS4-1", "uniprot_id": "A0A8M9PUS4_DANRE", "id": "A0A8M9PUS4-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSANGPAP-----------------------------------------------P---------------AATPAAPPAAAVPVPSVVPVGSL---AQKKRAQYAKSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHASCYF---QGTDILEDE-PAPCAVN-GHGRTCPING-TLCKEGWQGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGLELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EEEE-EESKRNRVTLASLMEKKKKGF---GWFSQSSDTHASMPASETESMNTENEKGEDEKAT--CCGPTC--------------------QKISKSKF---------------------------------------SRRWRRWNRLCRRNCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLAMFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEFEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQ-TKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTDDTKKPDEIDEIEDEAKAGEEDEKDN------------------------------------------------------AEEDEEEPDVP------AGPRPK-ISELVKKEKITPIPEGSAFFIFSNTNPVRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIVLGYADYVFT--------------------SMFTFEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKEGDVNQPIIQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLILLNTICLAVQHYGQSELFNYVMDILNMVFTAVFTVEMVLKLIAFKPR----------------------------HYFTDAWNTFDALIVVGSVVDIAITEVNPTEAPQVD--------ESGNT------EDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDHTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESDYNPGEE--MTCGSSFAIIYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQDYFRKFKKRKEEGLVG-VHPAQNNTAIALQAGLRTLHDIG-PEIRRAISCDLQDDELVDFIPEEDEEIYRRN--------GGLFGNHINHINGDPRRSSGHQTNATQRPLQVQPPPHYVHMEQPVGRLGRANAMAQQNHHRHHHHHHHHHHHNNSYNKSPKSTNINLNNANVSSLPNGGHN--RYYEHAPANGYPGSYYGEYDKPRTPHGQRRRYYETYIRSQGSDRRRPTIRREEE-----------------------------YEEDRYSG--EYYSGEEFYEDDSMLSG--------DRYPNSDQEYETPRGYHHPDSY--YEDDEQPLYHDSHRSPKRRLLPPTPQGNRRPSFNFECLRRQSSQDDLP-----HQRTALPLHLMQHQVMAVAGLDSSRAHRLSPTRSTRSWASPPPTPASKDR---TPYYTPLIRVDRP-LRDSAS-------------SSHSSIRKSSWYTDDPEYQ-----QRNFSPVHLQVPPEYR-NQYLQKRGSATSLVEAVLISEGLGRYAKDPKFVAATKHEIADACEMTIDEMESAASHLLNGGITPVVNGVNVFPILGHREYELQDVSASYSDEEPEPEPRPRYEEDLADEM---------------ICITTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JIS7-1", "uniprot_id": "CAC1F_MOUSE", "id": "Q9JIS7-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1F", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSE------------SEVGKDTTPEPSPANGTGPG--------------------------------------------------------------PEWGLCPGPPTVGTDT--SGASGLG---TPRRRTQHNKHKTVAVASAQRSPRALFCLTLTNPIRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPG--------DAP-HTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVVNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYF---LGSDMEAEEDPSPCASS-GSGRSCTLNH-TECRGRWPGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLRGYLDWITQAEELDLHDPSVDGNLASLAEEGRAGHRPQLSELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMTDTPGDEDEEEGTMASCTRCLN--------------------KIMKTRI---------------------------------------CRHFRRANRGLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPLWLTQTQEYANKVLLCLFTVEMLLKLYGLGPSVYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTH-TKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGREKSSEGNPPKENKVLVPGGENEDAKGARSEGAAPGM----------------------EEE--------------EEEEEEEEEEEEEEEENGAGHVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHIFTSLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFT--------------------SIFTVEILLKMTVFGAFLHRGSFCRSWFNLLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKESKGSFLIYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDANAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSRAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPK----------------------------HYFADAWNTFDALIVVGSVVDIAVTEVNNGGH------------LGESS------EDTSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGLVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGEE--FTCGSSFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPLNSDGTVTFNATLFALVRTSLKIKTEGNLDQANQELRMVIKKIWKRIKQKLLDEVIPPPD-EEEVTVGKFYATFLIQDYFRKFRRRKEKGLLG--REAPTSTSSALQAGLRSLQDLG-PEIRQALTYVTEEEEEEEEAVGQEAEEEEAE--------NNPEPYKDSIDSQP--QSRWNSRISVSLPVKEKLP-------------------------------------------DSLSTGPSDDDGLAP------NSRQPSVIQAGSQ---------------PHRRSSGVFMFTIP--EEGSIQL-------------------------------------------------KGTQGQDNQNE----------EQELPDWTPDLDRAGRDSFEPSP--FTTSLVQQHVNG-HMSTPTFAAPHACR-SEPSFTIQCLQRLGSCEDLP----IPGTYHRGRTSGPSRAQG-------------------SWAAP-----PQKG---RLLYAPLLLVEES-TVGEG-------------------------YLGKLGG-----PLRTFT--CLQVPGAHP-NPSHRKRGSADSLVEAVLISEGLGLFAQDPRFVALAKQEIADACHLTLDEMDSAASDLLAQR-----------------------TISLYSDEESILSR--FDEEDLGDEM---------------ACVHAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V9W8-1", "uniprot_id": "G3V9W8_RAT", "id": "G3V9W8-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSE------------SEVGKDTTPEPSPANGTGPG--------------------------------------------------------------PEWGLCPGPPTVGTDT--SGASGLG---TPRRRTQHNKHKTVVVASAQRSPRALFCLTLTNPIRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPG--------DAP-HTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYF---LGSDMEAEEDPSPCASS-GSGRSCTLNQ-TECRGRWPGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLRGYLDWITQAEELDLHDPSVDGNLASLAEEGRAGHRPQLSELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSITDTPGDEDEEEGTMASCTLCLN--------------------KIMKTKV---------------------------------------CRHFRRANRGLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQTQEYANKVLLCLFTVEMLLKLYGLGPSVYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTH-TKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGAAKDKGREKSSEGNPPQENKVLVPGGENEDTEGTKSEGAAPGM----------------------EEE--------------EEEEEEEEEE------NGAGHVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHVFTSLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFT--------------------SIFTVEILLKMTVFGAFLHQGSFCRSWFNLLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKECKGSFLIYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAHAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTVEMVLKIIAFKPK----------------------------HYFADAWNTFDALIVVGSVVDIAVTEVNNGGH------------LGESS------EDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGEE--FTCGSNFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPLNSDGTVTFNATLFALVRTSLRIKTEGNLDQANQELRMVIKKIWKRIKQKLLDEVIPPPD-EEEVTVGKFYATFLIQDYFRKFRRRKEKGLLG--ADAPTSTSSVLQAGLRSLQDLG-PEIRQALTYDTEEEEEEEEAAGQEAEEEEAE--------NNPETYKDSIDSQP--QAQWNSRISVSLPVKEKLP-------------------------------------------DSLSTGPSDDDGVAP------NSRQPSGLQAGSQ---------------PHRRSSGVFMFTIP--EEGSTQL-------------------------------------------------KGVQGQDNQNE----------EQEVPDWTPNLDEQAGMPSNPVL--LPPHWSQQHVNGHHVPRRRLLPPTPAG-RKPSFTIQCLQRQGSCEDLP----IPGTYHRGRTSGPGRAQG-------------------SWAAP-----PQKG---RLLYAPLLLVEES-TVGEG-------------------------YLGKLGG-----PLRTFT--CLQVPGAPS-DPSHRKRGSADSLVEAVLISEGLGLFAQDPRFVALAKQEIADACHLTLDEMDSAASDLLAQR-----------------------TTSLYSDEESILSR--FDEEDLGDEM---------------ACVHAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60840-1", "uniprot_id": "CAC1F_HUMAN", "id": "O60840-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1F", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSE------------SEGGKDTTPEPSPANGAGPG--------------------------------------------------------------PEWGLCPGPPAVEGES--SGASGLG---TPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPG--------DAP-HTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYF---LGSDMEAEEDPSPCASS-GSGRACTLNQ-TECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEEDLRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMTETQGDEDEEEGALASCTRCLN--------------------KIMKTRV---------------------------------------CRRLRRANRVLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLKLYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTH-TKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGGEKSNEKDLPQENEGLVPGVEKEEEEGARREGADMEE----------------------EEE--------------EEEEEEEEEEE-----EGAGGVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFT--------------------SIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPK----------------------------HYFTDAWNTFDALIVVGSIVDIAVTEVNNGGH------------LGESS------EDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGEE--FTCGSNFAIAYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRIVIKKIWKRMKQKLLDEVIPPPD-EEEVTVGKFYATFLIQDYFRKFRRRKEKGLLG--NDAAPSTSSALQAGLRSLQDLG-PEMRQALTCDTEEEEEE----GQEGVEEEDE--------KDLETNKATMVSQP--SARRGSGISVSLPVGDRLP-------------------------------------------DSLSFGPSDDDRGTP------TSSQPSVPQAGSN---------------THRRGSGALIFTIP--EEGNSQP-------------------------------------------------KGTKGQNKQDE----------DEEVPDRLSYLDEQAGTPPCSVL--LPPHRAQRYMDGHLVPRRRLLPPTPAG-RKPSFTIQCLQRQGSCEDLP----IPGTYHRGRNSGPNRAQG-------------------SWATP-----PQRG---RLLYAPLLLVEEG-AAGEG-------------------------YLGRSSG-----PLRTFT--CLHVPGTHS-DPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDLLAQG-----------------------TSSLYSDEESILSR--FDEEDLGDEM---------------ACVHAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW6-1", "uniprot_id": "A0A8M9PQW6_DANRE", "id": "A0A8M9PQW6-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYEENRKRNGYSNE------------EEEGGGEAEEEEEEGGEGGGG-----------------------------------------------GDEGDKE-----EKDEWDEEDRPKMNRTETLMSTTSSTA---TQKKKSQHVKKQVQGSNQVQRAPRALYCLKLNNPIRRAALHLVEWKPFDIFILLAIFANCVALGVSKPFPEDDSNATNHDLEQVEYVFLIIFTIETFLKILAYGLVMHPSSYIRNGWNLLDFVIVIVGLFSVVLETVTHKSG--------ETTSHTPGKPGGLDVKALRAFRVLRPLRLVSGVPSLQIVLNSIMKAMVPLLHISLLVLFVIIIYAIIGLELFIGRMHRTCFF---IGTDNYADDDPLPCAFA-GHGRQCYVNG-SECRGKWEGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMNDAIGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLCGYMDWITQAEDIDEFD-----------EDG--NRRVTLRDLADKKRGKFGWFSHSN------ETHASLPASETASENTENIDEEHTD----CCAACCA--------------------RIMKIPC---------------------------------------CRALRRWNRCIRRNCRTAVKSVTFYWLVLILVFLNTALSASEHYNQPEWLTDVQDIANKVLLSLFTVEMLLKMYSLGLQVYFVAFFNRFDCFVVCGGILETVLVEMEIMPPLGISVLRCVRLLRIFKVTRHWTALSNLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLFGGKFNFDETQ-TKRSTFDSFPQALLTCFQILTGEDWNVVMYDGIMAYGGPVFPGMIVCLYFVILFICGNYILLNVFLAIAVDNLAGGDGDNKKNE-EKKEGEAEP------------AEEENGEVKVDMDEEY----------------------EEE--------------EEPEEGDDEE-------GKIQLNVADFAPPKEKILPIPEGSAFFCLSKTNPIRVGCHTLIHHHIFTNLILVFIILSSISLAAEDPIRAHSFRNNVLGYADYAFT--------------------SIFTVEILLKMTVHGAFLHEGSFCRNWFNLLDLLVVSVSLVSFFLHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKNTPEQCKGTFVVYKDGDVSHPMVRERIWLNSDFNFDNVLMGMMALFTVSTFEGWPALLYKAIDANGENHGPIYNYRVEISIFFIVYIIIIAFFMMNIFVGFVIITFREQGEAEFKNCELDKNQRQCVEYALKAQPLKLYIPKNPVQYKFWSIINSTGFEYVMFVLILLNTVTLAVQHYDQSKFFSQVMDILNMVFTGLFTVEMIIKLMALRLR----------------------------HYFVDAWNSFDALIVVGSVVDIVVTEFS-------------------SS------EDSSRVSITFFRLFRVMRLVKLLSKGEGIRTLLWTFVKSLQALPYVALLIAMIFFIYAVIGMQTFGKIAMQDHTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGKRCDAESDFEPGEE--FSCGSNIAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNADGTVTFNATLFALVRTALKIKTDGNPDQENEELRIIIKKIWKRTKPKVLDEVIPPPA-EEEVTVGKFYATFLIQDYFRKFRKRKEKVGLEEEGNGNPTALQLCQAGLRTLQELG-PEMRLAMNEDLEEEEEG---LDEEQEEDDAH--------YKNENGYAHTEPLS--RSRRSSLATTPIGAPVPVPG-------------------------------DGILNGGLGRRSSLAKTPNGNGALENENFRRRDSMRSSIHYQHKNGVIDQLPKRPSYYKYPRRDSRDRFSSPLSRREEGGEYPGE-----------------------------------------------QRFYGKDEDSESVISRERHGYPEDSTIFQGHRDMYDGHSMRHPV--YGNHYGNSYGDGRRTARRRLLPATPTG-RKASFNIQCLRRQGSSDDLP----IPGTYHQNSPPCRARSQGYSSYDSRRSSARSSTGSTASWANTG----PRRG---RLLYAPLILVEEEGAAGAGGVGIWDKKPGGVGVPASVRHPGSGWYSGPSAGGGGQ-PYRAYT--TLRVPTQLS-PHYSEKRGSADSLVEAVLISEGLGLYAKDPKFVAFAKREIADACHMTIDEMESAASDLLNRGGSEKSQK----------FMNHTDTGLVYSDEEPIRS---HEEEELADEM---------------TCVTSF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01815-1", "uniprot_id": "CAC1C_MOUSE", "id": "Q01815-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVNENTRMYVPEENHQ-----------GSNYGSPRPAHAN-MNANAAAG---------------------------------------------LAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSS---TQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADG----------ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN-QEGIIDVPAEEDPSPCALETGHGRQCQNG--TVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EDEGMDEDKPR---------------------------NMSMPTSETESVNTENVAGGDIEGE--NCGARLAH-------------------RISKSKF---------------------------------------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDT-AGEEDEEEPEMP------VGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFT--------------------SIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK----------------------------GYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPS--------MSA------EENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG---KPSQRNALSLQAGLRTLHDIG-PEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR--RAGGLFGNHVTYYQ-SDSRGNFPQTFATQRPLHINKTGNN-----------------------------------QADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG-RFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKR-----------------------------------CHSRESQGATVNQEIFPDETR-SVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLT-----CPEEDKREIQPSPKRSFLRSASLG-RRASFHLECLKRQ-----KDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSR---GRPLRPIPTLRLEGAESSEKLN-------------SSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAG-APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRG-RSEEALADSR---------------SYVSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22002-1", "uniprot_id": "CAC1C_RAT", "id": "P22002-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIRAFAQPSTPPYQPLSSCLSEDTERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHAN-MNANAAAG---------------------------------------------LAPEHIPTPGAALSWLAAIDAARQAKLMGSAGNATISTVSS---TQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADG----------ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN-QEGIIDVPAEEDPSPCALETGHGRQCQNG--TVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EDEGMDEDKPR---------------------------NMSMPTSETESVNTENVAGGDIEGE--NCGARLAH-------------------RISKSKF---------------------------------------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISCWRCVRLLRIFKITRYWNSLSNLVASLLNSLRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFISPNYILLNLFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDT-AGEEDEEEPEMP------VGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFT--------------------TIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLR-INRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAESKGNYITYKTGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLPRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPS--------MSA------EENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG---KPSQRNALSLQAGLRTLHDIG-PEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR--RAGGLFGNHVSYYQ-SDSRSNFPQTFATQRPLHINKTGNN-----------------------------------QADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG-RFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKR-----------------------------------CHSRESQGATVSQDMFPDETRSSVRLSEEVEYCSEPSLLSTDILSYQDDENRQLT-----CLEEDKREIQPCPKRSFLRSASLG-RRASFHLECLKRQ-----KDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPSTFPRPRPTPPVTPGSR---GRPLQPIPTLRLEGAESSEKLN-------------SSFPSIHCSSWSEETTACSGGSSMARRARPVSLTVPSQAG-APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVVPEDESCVYALGRG-RSEEALPDSR---------------SYVSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13936-1", "uniprot_id": "CAC1C_HUMAN", "id": "Q13936-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVNENTRMYIPEENHQ-----------GSNYGSPRPAHAN-MNANAAAG---------------------------------------------LAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSS---TQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADG----------ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN-QEGIADVPAEDDPSPCALETGHGRQCQNG--TVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------EDEGMDEEKPR---------------------------NMSMPTSETESVNTENVAGGDIEGE--NCGARLAH-------------------RISKSKF---------------------------------------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPET-TGEEDEEEPEMP------VGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS--------MNA------EENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG---KPSQRNALSLQAGLRTLHDIG-PEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR--RAGGLFGNHVSYYQ-SDGRSAFPQTFTTQRPLHINKAGSS-----------------------------------QGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG-RLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLT-----LPEEDKRDIRQSPKRGFLRSASLG-RRASFHLECLKRQ-----KDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSR---GWPPQPVPTLRLEGVESSEKLN-------------SSFPSIHCGSWAETTPGG-GGSSAARRVRPVSLMVPSQAG-APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGR--PSEEELQDSR---------------VYVSSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TNI5-1", "uniprot_id": "A0AB32TNI5_DANRE", "id": "A0AB32TNI5-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRGLFSWRRLKHERLEEEVEVRFKGKLVSERELGYTHVRPGGSNYSSPSLAPVPSLNEDEHVGGGGG--------------------------------------VLGLAPEHIPTPGAPLSWQAAIDAARQAKLMGTTG-APISTASS---TQRKRQHYTKPKKQASTASTRPPRALLCLTLKNPIRRACINIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDG----------GTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGHKGHIAEEKPAPCAPSSAHGRHCSPPNITQCMMGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----------DDEGLDDDKPR---------------------------NLSMPASENESVNTDNAPAGDMEGE--TCCTRMAN-------------------RISKSKF---------------------------------------SRYSRRWNRLCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHHQQPEWLTNVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDET---RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKRQNSEKPPLEDEKKEEKIELKSITSDGETPTATKINIDEYTGEDNEEKNPYPVNDFPAGEDDEEEPEMP------VGPRPRPLSDIQLKEKAVPMPQAKAFFIFSPSNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADYVFT--------------------GIFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTSLLQFMFACIGVQLFKGKFFYCTDTSKQTQAECRGAYILYKDGNVGKPEKAQRSWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHAEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQSQSFNKAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNT------EDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDNSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSEINHSSE---DCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVA---KIPPKTALSLQAGLRTLHDMG-PEIRRAISGDLTVEEELERAMKETVCAASEDDIFRVKRSGGLFGNHVNYYHQSDGHVSFPQSFTTQRPLHISKSGS------------------------------------PGEAESPSHQKLVDSTFTPSSYSSSGSNANINNANNTAIGHRYPKP-----TVSTVDGQTGPPLTTIPLPRPTWCFPNKRS--------------------------CFYDTFMRSDSSDSRLPIIRREEASTDETYDETFLDE----RDQAMLSMDMLEFQDEESKQLAPMVEAEVGEERRPWQSPRRRAFLCPTALG-RRSSFHLECLRKH-----NRP--DVSQKTALPLHLVHHQALAVAGLSPLLRRSHSPTLFTRLCSTPPASPSGRSGGGPCYQPVPSLRLEGSGSYEKLN-------------SSMPSVNCSSWYSD----SNGNHSGRAQRPVSLTVPPVTRRDSISLAHGSAGSLVEAVLISEGLGRYAHDPSFIQVAKQEIAEACDMTMEEMENAADNILNANAPPNANGNLLPFIQCRDTGSQESRCSLSLGLSPATGSDGALEAELEESEGAGQRNSPLMEDEDMECVTSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02789-1", "uniprot_id": "CAC1S_MOUSE", "id": "Q02789-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1S", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPSPQDE---GLRKKQ----PKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQT---------NTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCART-GSGRPCTING-SECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDD----------LREGKLS--------------------------------LDEGGSDTESLYEIEGLNKIIQ----------------------------------------------------------------------------FIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTE-VRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSKG-LPDKSEEERATVTKKLEQK-SKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFP--------GDDEEDEPEIP------VSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFT--------------------AVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMVLKLIAFKPR----------------------------GYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDP------DESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEE--HTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIG-DDEVTVGKFYATFLIQEHFRKFMKRQEE-YYGYRP---KKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFR-----RTGGLFG-QVDNFLER--TNSLPPVMANQRPLQFAEI-----------------------------------------EMEELESPVFLEDFPQNPGTHPLARANTNNANANVAY------------------------------------------------------------------------------------------------------------GNSSHRNNPVFSSICYEREFLG----------EADMPVTREGPLSQPCRASGPHSRSHVDKLKRPMTQRGMPEGQVPPSPCQVTGAKAEHPVQKEGK-------------------------------------GPTSRFLETPNSRNFE------------------------------------------------EHVPRNSAHRCTAPATAMLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEVEVAATELLK-QESPEGG-------------------AVPWEP---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02485-1", "uniprot_id": "CAC1S_RAT", "id": "Q02485-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1S", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPSSPQDE---GLRKKQ----PKKPVPEILPRPPRALFCLTLQNPLRKACISVVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNIIQT---------NTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCART-GSGRPCTING-SECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDD----------LREGKLS--------------------------------LDEGGSDTESLYEIEGLNKIIQ----------------------------------------------------------------------------FIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTE-VRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSRG-LPDKSEEERSTMTKKLEQK-PKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFP--------GDDEEDEPEIP------ASPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFT--------------------AVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLIAFKPR----------------------------GYFGDPWNVFDFLIVIGSIIDVILSEIDTLLASSGGLYCLGGGCGNVDP------DESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKRCDPESDYAPGEE--YACGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIG-DDEVTVGKFYATFLIQEHFRKFMKRQEE-YYGYRP---KKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFR-----RTGGLFG-QVDNFLER--TNSLPPVMANQRPLQFAEM-----------------------------------------EMEELESPVFLEDFPQNPGTHPLARANTNNANANVAY------------------------------------------------------------------------------------------------------------GNSSHRNSPVFSSIRYERELLE----------EAGRPVTREGPFSQPCSVSGVNSRSHVDKLERQMSQRRMPKGQVPPSPCQLS--QEKHPVHEEGK-------------------------------------GPRSWSTETSDSESFE------------------------------------------------ERVPRNSAHKCTAPATTMLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEVEVAATELLK-RESPKGG-------------------AMPREP---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13698-1", "uniprot_id": "CAC1S_HUMAN", "id": "Q13698-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1S", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPSSPQDE---GLRKKQ----PKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQS---------HTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCART-GSGRRCTING-SECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVED----------FREGKLS--------------------------------LDEGGSDTESLYEIAGLNKIIQ----------------------------------------------------------------------------FIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTE-VRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSKG-LPDKSEEEKSTMAKKLEQK-PKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFP--------GDDEEDEPEIP------LSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFT--------------------SVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKAR----------------------------GYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDP------DESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEE--YTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIG-DDEVTVGKFYATFLIQEHFRKFMKRQEE-YYGYRP---KKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAMVEAAMEEGIFR-----RTGGLFG-QVDNFLER--TNSLPPVMANQRPLQFAEI-----------------------------------------EMEEMESPVFLEDFPQDPRTNPLARANTNNANANVAY------------------------------------------------------------------------------------------------------------GNSNHSNSHVFSSVHYEREFPE----------ETETPATRGRALGQPCRVLGPHSKPCVEMLKGLLTQRAMPRGQAPPAPCQCPRVESSMPEDRKSS-------------------------------------TPGSLHEETPHSRSTR------------------------------------------------ENTSR-----CSAPATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKGREAPEGM-------------------ASSLGCLNLGSSLGSLDQHQGSQET--------------LIPPRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BFL7-1", "uniprot_id": "A0A8M2BFL7_DANRE", "id": "A0A8M2BFL7-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGNGEAP-----------------------------------------------------------------------------------------MSSFIMDEE---TLKRKQREKLKKLQATGGNPRPARSLLFLTLKNPFRKACINIVEWKPFEIIILLTIFANCVALAVFMPMPEEDTNNTNSNLESLEYIFLIIFTMECFLKIVAYGFLFHADAYLRNCWNILDFVIVTMGLFTVVVDFINSISG---------VEAPVEQKGG-FDMKALRAFRVLRPLRLVSGVPSLQVVMSSILKSMLPLFHISLLVFFMVTIYAIIGLELFKCKMHKTCYHTGTDIIATGDDAQAAPCAQA-GNGRRCTLNG-TECRGDWPGPNNGITHFDNLGFSMLTVYQCITTQGWTDVLYWVNDAIGMEWPWLYFVTLILLGSFFILNLVLGVLCGEFTKEREKSSRSGEYQILRERQQFDEDLKGYMEWITQAEVMDNDQ----------EGQGLLP--------------------------------LQDG-SETETLYELDILNKLMF----------------------------------------------------------------------------YVRHARRWNRFFRRKCRVWVKSKLFYWLVILLVFFNTLAIATEHHQQPDSLTNFQDNTNKALLSLFAVEMFLKMYAMGLPSYFMSLFNRFDCFVVSVGILELILVRMDVMSVMGISVLRCIRLLRIIKITRHWTTLSNLVASLLNSVRSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDDR-VRRSNFDNFPQALITVFQILTGEGWNYVMYDGIMAHGGPAIPGILVSIYFIILFICGNYILLNVFLAIAVDNLAEAESLTSAQKEKAEEKKRKRLLRENLPDKGEEEKALLAKKLAEQRAKIDGIPTTAKLKVDEFESNVNEIKDPFPPADFP--------GDDEEEEPEIP------LSPRPRPMADLQLKETEVPMPEASAFFLFGPQNKFRKLCHRIINATTFTNIILLFILLSSISLAAEDPIDPMSFRNQVLAYADYVFT--------------------SVFTAEIVLKMTTYGAFLHKGSFCRNSFNILDLIVVGVSLLSMGMESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVTMLLDFMFACIGVQLFKGKFLYCTDPLKMTAEECQGTFIQHQENALHDMVVSQRLWMNSDLNFDNVLNGMLALFTVSTFEGWPDLLYKAIDSNLENMGPVYNNHIEISIFFIVYLILIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSCYFEYLMFLLIMLNTMCLGMQHCKQSDHITDLADTLNVIFTVLFTVEMILKLGAFKAK----------------------------GYFGDPWNVFDFVIVVGSIVDVILSEIDAALAAQGGLYCLTG-CSEVNPMQAIADSENMSVSITLFRLFRVMRLVKLLNRFEGIRNLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALLDGTIINRNNNFQTFPQAVLLLFRCATGEGWHEIMLGCLYGQRCDPKSEYLPGEE--YTCGSGFAILYFMSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPQHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLISMNMPLNSDGTVTFNATLFALVRTGLKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPALG-DDEVTVGKFYATFLIQDHFRKFMKRQEE-YYGYRPSKKNKNTTEIQAGLRSIEEEAAPELQRAISGDLLNDEEMDRAMEESG-EESIYR-----RAGGLFGNHVDPFSME--RGTGAAQVTSQRPLQLADS-----------------------------------------RADRTET------------TYASYHANNNNTNNNNRR------------------------------------------------------------------------------------------------------------RHS-----------------------------------------------------------------------------------------RCEPH-------------------------------------FPACISASRLHS---------------------------------------------------------------PASAAEFLIQQVLTSGGLESLASDWRFVSVTKSEMAAALHLDLQELERKSAAILN---QHKGQ-------------------CVLRKKKMETSHSDITHCHV-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24270-1", "uniprot_id": "CAC1D_DROME", "id": "Q24270-1", "name": "Voltage-dependent calcium channel type D subunit alpha-1", "aln": "MNTGDRKEQASLTPQQQQSPQQPEQQQPITRHDALDSSSANNKLNHKHNNDKDKDTTSDKNWEAGRDLLPASVVIVDESCASKSQKQPIEPSIVSRSGATSSSQRRRQLQFQRQKEAKLYDRGDGDRDREREREASTSTSTSTSASTTTTNTVMGGGELVNCIAYDDNTLVIERKPSPSSPSTSRRYLKAETPTRGSRKYNRKSSAKSDLEVVVVKPEHHHQHRSPTITLPVPANPLTTSASAGSSPTGAGLAAGLGTASGTVLQQSCSALDPPEDSNQPSGTRRRPTSTELALSNVTSQIVNNATYKLDFKQRRHKSNNGGSESGSLTGIATGPATSPAGPTGPTSSSGKRRKSSCTSCGGGGISAPPPRLTPEEAWQLQPQNSVTSAGSTNSSFSSGGGRDDNSSYSAVGGDSSSSNSCNCDITGDNSTLHGFGVGDVCSFIADCDDNSEDDDGDPNNQDLSSQTLRTAAIVAAVAAAAKEQAQEQSLADCESFSDRRQDADEDVRIIQDCCGGNNDSLEDVGEVDDNADVVVRKNSRNRPSIRRTCRITEEDDDEDENADYGDFDREDQELDDEEPEGTTIDIDEQEQQHDQGDSAEEEDDDEDVDEYFEEEEDDTQAFSPFYSSSAELIDNFGGGAGKFFNIMDFERGASGEGGFSPNGNGGPGSGDVSRTARYDSGEGDLGGGNNIMGIDSMGIANIPETMNGTTIGPSGAGGQKGGAAAGAAGQKRQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQL---------------------MKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRD----EITGEYEENIRPCGVG----YQCPPGY--KCYGGWDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDA-----------VGGLISDGKG---------------------------KQPNEMDSTENLGEEMPEVQMTESR-----------------------------------------------------------------------WRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPHDESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----------DEDKMDHETLSDEEVR----------EMCEEEEEVDEEG-----MITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFT--------------------AVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFK----------------------------NYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKS-----AGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE---PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGNIDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFKKRKEQEGKE---GHPDSNTVTLQAGLRTLHEVS-PALKRAISGNLDELDQEPEPMHRRHHTLFGSVWSSIRRHGNGTFRRSAKATASQSNGALAIGGSASAALGVGGS-----------------------------------------SLVLGSSDPAGGDYLYDTLNRSVADGVNNITRNIMQAR---------------LAAAGKLQDELQGAGSGGELRTFG-----------------------------------------------------ESISMRPLAKNGGGAATVAGTLPPEANAINYDNRNRGILLHPYNNVYAPNGALPGHERMIQSTPASPYDQRRLPTSSDMNGLAESLIGGVLAAEGLGKYCDSEFVGTAAREMREALDMTPEEMNLAAHQILSNEHSLSLIGSSNGSIFGGSAGGLGGAGSGGVGG---------------------------------------------LGGSSSIR-NAFGGSGSGPSSLSPQHQPYSGTLNSPPIPDNRLRRVATVTTTNNNNKSQVSQNNSNSLNVRANANSQMN-----------------MSPTGQPVQQQSPLRGQGNQTYSS---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. *:* *.: **:* .: :*:****: :**::*****:**.: * * .*.* * ** :** **::*: * :*::* *:: * .: :*. **:*** ** :* ::. :. :*:*********************::*:.**:*:::**:**:***:*:: ********** ::* :* : **. * * * **: ***:***: ::****:**:: :******* ::**:* : *:**::::::*:**::**:****.***:***:*:. * :* **:**::*** **:.****.* :: ... . : : ** * *: *** ** ::.:* :** ::**: * * *: :* :: :*: **::*:*.:* *. ::*****.*:* .* * *.. * :*:* **:****::*:*::* :***********::************::**:*****:***:::* * .** * *:*:: **::***.*. :** ** *:** * :..:**:***:. *****::********** .:. : . : :* : . . *:* ..:** :. * .* ** : : * .:** *::** ****:*: . * :* * ** :** *: **: .* .** *:***. **:**::** ***:* *.**.*************** *************::**: *****::** **:**** *********: *.* * . :. * : : . * * :. :.**:* .*::**:******** *** :**: *: **::* : :: ::*:*:*::****:********:**: :** *::**:******:*:::****:*: ****: **:.* :.* *** :* **::**: *.::. *. . : **: ** :*::*:::*: *:: : ** *.** ** :**:**.:*: :* . . :* :*********:***.: **:*.*****:**:**********.::******:*** ** :*: . . *. ******* ****:***.****.*::*::.. : * **: :* **::*::**:**:************************:***** :*:**** *.*********:***:*.*******:****:*****:.**:***:**** *******:***.* ***:** :: *.*** :*:***: . *:**:*:*. ::**********:***::**:* :*:*: *****::.: . * : ::. : . : . .. * * . :: : .::. * ", "identical_positions": 688, "similar_positions": 389, "identity": "22.29%" }, { "cls_id": "homologset.agr.FB:FBgn0001992", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51590-1", "uniprot_id": "CP2J3_RAT", "id": "P51590-1", "name": "Cytochrome P450 2J3", "aln": "----------------------MLVTAGSLLGAIWTVLHLRILLLAAVTFLFL----ADFLKHRRPKNYPPGPWRLPLVGCLFHLDPKQP------------------HLSLQQFV---KKYGNVLSLDFAN-IPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHLFNKN---GLIFS-SGQTWKEQRRFALMTLRNFGLGKKSLEQRIQEEAYHLVEAIKD------EGGLPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLP--GSHQTLFSNWRKLKLFISDIIKNHRRDWDPDEP-RDFIDAFLKEMAK-YPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQE------------------KMQAEIDRVIGQGRQPNLA-DRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTFKPPVNEKLS--LQFRMS-VTISPVSHRLCAIPRL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54750-1", "uniprot_id": "CP2J6_MOUSE", "id": "O54750-1", "name": "Cytochrome P450 2J6", "aln": "----------------------MLAATGSLLATIWAALHPRTLLVAAVTFLLL----ADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQP------------------HLSIQPLV---KKYGNIFSLNLGD-ITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKN---GLIFS-SGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIRE------EEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIP--GSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDEP-RDFIDAFLKEMTK-YPEKTT-SFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQE------------------KVQAEIDRVIGQKRAARLA-DRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLS--PKFRNG-LTLSPVSHRICAVPRQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51589-1", "uniprot_id": "CP2J2_HUMAN", "id": "P51589-1", "name": "Cytochrome P450 2J2", "aln": "----------------------MLAAMGSLAAALWAVVHPRTLLLGTVAFLLA----ADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQS------------------HLEVQLFV---KKYGNLFSLELGD-ISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKN---GLIMS-SGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKE------ENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP--GPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAET-RDFIDAYLKEMSK-HTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQE------------------KVQAEIDRVIGQGQQPSTA-ARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLE-NGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS--LKFRMG-ITISPVSHRLCAVPQV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JTQ9-1", "uniprot_id": "A0A0G2JTQ9_RAT", "id": "A0A0G2JTQ9-1", "name": "unspecific monooxygenase", "aln": "----------------------MLATVGSLLAKIWSAINFWTLLLTLLTFLLL----ADYLKNRRPNNYPPGPWRLPFVGNLFQFDLNISHL----------------HLRIQQFV---KKYGNLISLDFGN-ISVVVITGLPLIKEALINNEQNFLKRPIVPSRYRVFKDN---GIFFA-NVHKWKEQRRFALTMLKNFGLGKKSLEQCIQEEAHHLVEVIGE------EKGQPFDPHFRINNAVSNIICSITFGERFEYDDSQFQELLKLADEVICSEASMTSVLYNVFPLIFKYLP--GPHQTVFKNWEKLKSIVANMIDRHRKDWNPDEP-RDFVDAFLTEMTK-YPDKTTTSFNEENLIATTLDLFFAGTETTSTTLRWALLYITLNPEVQE------------------KVHSEIDRVIGHGRLPSTD-DQDAMPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRDSFLPFSVGKRACPGEKLAKSELFIFFTALMQNFTFKAPTNEKLS--LKLRKG-LSLYPVSYRICAVPR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8U1-1", "uniprot_id": "A0A140T8U1_MOUSE", "id": "A0A140T8U1-1", "name": "unspecific monooxygenase", "aln": "----------------------MLSTVGSLVARIWSAIHLWTLLLTLLVFRLL----ADYLKNRRPKNYPPGPWRLPFVGNLFQFDLDVSQL----------------HLRIQLFV---KKYGNLISIDFGN-ISSVVITGLPLIKEAFTDMEQNLLKRPIIPSRKHVFKDN---GIIFS-SGQKWKEQRRFALMILKSFGLGKKSLEQRIQEEAYHLVKAMEE------EKGQPFDPHFRINSAVSNIICSINFGERFEYGDNKFQELLKITNETLSAETSMMLVLYNALPSIMKYLP--GPHQTVFRNWERLKMIVYHMMESHRKDWNPDEP-RDFIDAFLTEMTK-YPDKTTTSFNEENLICSCLDLFIAGTETSSTALRWALLYMTLNPEVQE------------------RVHSEIDGVIGQWRQPSTG-DRDSMPYTNAVIHEVLRMGNIVPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDIFNPEHFLE-NGQFKKRESFLPFSMGKRACPGEQLARTELFIFFTALMQKFTFKAPVNEKLS--LKFRMS-VPISPVSYCICAVPRQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UXT0-1", "uniprot_id": "G3UXT0_MOUSE", "id": "G3UXT0-1", "name": "unspecific monooxygenase", "aln": "----------------------MLATEDTFETAIWALLHFKTLVLAAVTFMLL----AHYLKTQRPKNYPPGPWRLPFVGNLFQLDLEQP------------------HVVIQQFV---KKYGNLTSLDFGN-IPSVIITGLPLIKEVFTNMEQNFLNRPITPIRKRVFNNN---GLIIS-NGQTWKEQRRFALMTLKNFGLGKKSLEQRIQKEADCLVEAIGE------EKGQPFDPHFKINSAVSNIICTFAFGERFEYEDSHFHELLRLLDEATCLEASMMCQLYNVFPSIIQYVP--GSHQTVLRNWEKLKLFIYQMMESHRKDWNPDEP-RDFIDAFLTEMSK-YGDKTTTSFNEENLINSTLDLFFAGSETTTNTLRWALLYITTNPEVQE------------------KVHSEIDRVIGHGRQPSTD-DRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHFLE-NGQFKKRESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTFKPPINEKLS--LKFRNG-LTLSPVSHCICAVPRH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54749-1", "uniprot_id": "CP2J5_MOUSE", "id": "O54749-1", "name": "Cytochrome P450 2J5", "aln": "----------------------MIMFLSSLVTTFWEALHLKTLVLAVVTFLFL----INILRSRHPKNYPPGPWRLPFVGNFFQIDTKQT------------------HLVLQQFV---KKYGNVFSLELGQ-SPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKN---GLVVS-NGQTWKEQRRLALMALRNFGLGKKSLEERIQEETHHLVEAIRE------EGGQPFNPHLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSAGQLYNGFPCIMKYLP--GPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDEP-RDFIDAFLIEMQK-DPDRTT-SFNEENLISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQE------------------NVQAEIDRVIGHKRQVSLS-DRESMPYTNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKPPINEKLS--LKFRMG-LILSPASYRICAIPRV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ56-1", "uniprot_id": "A0A8M1PZ56_DANRE", "id": "A0A8M1PZ56-1", "name": "", "aln": "----------------------------MDMLHFYEWIDIKSILIFVCVFLLL----SDFIKNKTPKNFPPGPWSLPIIGDIHHIDPSKL------------------HLQLSEFA---EKYGKIFSLRLFG-PRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDK---GLVAS-SGYKWKQQRRFALSTLRNFGLGKKNLEPSINLESGFLNEAISN------EQGQPFDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMRLLP--GPHKRIIALWGKLIEFVGEKVNEHKVDHDPLNP-RDYIDCFLDEMEK-HKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQA------------------KVQQEIDVIVGGSRQPSVS-DRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEKYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPS--LDYNLG-ATHCPQPYKLCAVPH----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TES7-1", "uniprot_id": "A0AB32TES7_DANRE", "id": "A0AB32TES7-1", "name": "", "aln": "-------------------------MSSVFSQLIGQWLDVQGFLIFLCVLLLV----KHFR-DVYSKNMPPGPFPLPFVGNLTNIGFSDP------------------LGSFQRIA---EKYGDVCTLYLGT-KPCILMTGYETLKEAFVEQADIFTDRPYFPIVDKLGNGK---GLIMS-SGHMWRQQRRFALATLKYFGVGKKTLENAILQECRFLCDSLQA------ERGLPFDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGRLYNEFPTLMSLLP--GKHQTAFASMSKLQPFLKEEIIKHQQDREPSSP-RDYIDCYLEEIEK-CK-DSDAEFTEENLMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQE------------------KVQSEIDQVIGQTRQPLMD-DRTNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPKGVIVLPMLKPILLDKKEYSTPYDFNPAHFLDQNGKFLKKENFIPFSIGKRMCPGEQLARMELFLFFISLMQHFTFLPVEGQKLS--LKGTTS-VSSAPQPFQIRAVPR----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F7FAJ1-1", "uniprot_id": "F7FAJ1_RAT", "id": "F7FAJ1-1", "name": "Vitamin D 25-hydroxylase", "aln": "MGVRQGWKARPGLSETNWFPPQPWPMFQLPGVQTCAGALAGAFLLLLLVLVV-----RQLLRQRRPAGFPPGPPRLPFIGNICSLALSADLP----------------HVYMRKQS---RVFGEIFSLDLGG-ISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMG---GLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIET------YKGRPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPF--GKHQRLFRNADVVYDFLSKLIEKAAVNRKPHLP-QNFVDAYLDEMDKGQNDP-LSTFSKENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQG------------------QVHKEIDLIMGHDRRPSWE-DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSSGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFP-HELVPN-LKPRLG-MTLQPQAYLICAERR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX98-1", "uniprot_id": "CP2U1_MOUSE", "id": "Q9CX98-1", "name": "Cytochrome P450 2U1", "aln": "MSSLG--DQRPAAGEQ-------------PGARLHVRATGGALLLCLLAVLLG----WVWLRRQRACGIPPGPKPRPLVGNFGHLLVPRFLRPQFWLGSGSQTDTVGQHVYLARMA---RVYGNIFSFFIGH-RLVVVLSDFHSVREALVQQAEVFSDRPRMPLISIMTKEK---GIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKEAMQK------HGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINICPWFYYLPF--GPFKELRQIERDISCFLKNIIREHQESLDASNP-QDFIDMYLLHMEEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQK------------------KVHEEIERVIGCDRAPSLT-DKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFALPEGSEKPV-MTGRFG-LTLAPHPFNVTISKR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NWJ8-1", "uniprot_id": "A0A8M1NWJ8_DANRE", "id": "A0A8M1NWJ8-1", "name": "", "aln": "--------------------------MLAALLKLDLSSVGLSLFLGLIFLVLF----EIFRIHSCKGRFPPGPTPLPFVGSIPHFLNN--------------------PMGFIKSL---SQYGEMTTVYPGR-KPAIILNTLQLMKEALVQNGSSFSGRPPVPVFNWVTDGY---GIVMATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISEFLK------AEGKPFNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYLLEIIKENIIQAGSLVGQVFNLVPIIKHVP---GPHQKIYQNGQAFKSFIRESVKEHRQTLDPDSP-RDFIDAYLLEMEK-QKSTQDSTFHEDNMVMAVGDLFLAGSDTTATTIRWGLIYLTQNPDVQE------------------RCHEEIVRVLGFDRLPSMD-DRDRLPYTHATVHEFQRCANLVPTGVPHQTTQATKLRGYDIPQGTQILINLTEILTNKEHWKHPDTFNPENFLDDKGHFFKPEAFLPFSLGPRACLGETLAKAELFLFVTSLLQRIRFSWPTGEKLPD-MNGIFG-IVRSPKPFNIICHSRGSKH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TDH5-1", "uniprot_id": "A0AB32TDH5_DANRE", "id": "A0AB32TDH5-1", "name": "", "aln": "--------------------------MLVGLLKLDLSSVGLSLFLGLFCLALF----EICRIRIYKGRYPPGPTPLPFVGTIPHFLKN--------------------PMGFIRSL---SQYGEMTTVYLGR-KPAIILNALQLMKEAFVQNGSSFSGRPPVPVLTWVNQGY---GIIMAMDGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLICELLR------VEGKPFNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYLLEIIKENLDLAGSFAGQMVNLVPIIKNLP---GPHQKIYQNGEEFKSFIRESVKAHRETLDPDSP-RDFIDAYLLEMEK-QKSTQDSTFHEDNMVMSVGDLFFAGTDTTATTIRWGLLYLTQNPDVQE------------------RCHDEIVQVLGFDRFPIMD-DRDQLPYTLATVHEIQRCANVAPSGVPHQTTKPIKLRGYDIPQGTQILINLMGILANKEHWKHPDTFNPENFLDDKGHFFKPEAFLPFSLGPRACLGETLAKTELFLFVTSLLQRIRFSWPTGEKWPD-MNRILS-VIRSPEPFNIICNSRDSEH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IQ46-1", "uniprot_id": "A0A0R4IQ46_DANRE", "id": "A0A0R4IQ46-1", "name": "", "aln": "--------------------------MFASLLKLDLASVGLTLFLGLIFLVVF----EIFRIRSYSGRFPPGPTPLPFVGTIPHFLKD--------------------SMGFIRSL---SQYGEMTTVYLGR-KPAMVLNTLQVIKEAIVQNGTSSSGRPSIPILTWITEGY---GIVLATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLVPEMLK------LEGKPFDPQHAIQNAVSNIICSIVFGDRFEYDNKRFEYLLEIIKENINQAGSLIGQVFNLIPIIKHFP---GPHQKIYQNAEELKSFIRESTKSHRETLDPDSP-RDFIDAYLLEMEK-QKSSQDSSFHEDNMVMSVADLFLAGSDTTATTIRWGLIYLTQNPDVQE------------------RCHEEIVRVLGYDRLPCMD-DRDRLPYTLATVHELQRCGNIVPSSVPHETTQPMKLRGYDIPQGTQMLINLSDILANKEHWKHPDTFNPENFLDDKGHFYRPEAFLPFSLGPRVCLGETLAKTELFLFITSLLQRIRFSWPTGEKWPN-MDGIVS-VVRSPEPFKIICHSRGSKE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N004-1", "uniprot_id": "A0A8M1N004_DANRE", "id": "A0A8M1N004-1", "name": "", "aln": "--------------------------MFGALVKLDLSSVGLTLLLGLILLVLF----EIFRIHSYKSRFPPGPTPLPFVGNLPHLLRD--------------------PMGFNRLM---AQYGEMSTMYLGK-KPAIVLNTIQVAKEALVQ--EAFAGRPCLPVIDWTSNGC---GIIMATFNNSWKQQRRFALHTLRNFGLGKKSIESRVLEESQYLFAELLK------DEGEPVNPHHALQNAVSNIFCSIMFGERFDYDNKRLGYLLKILNENMMLTGSAIGQIFNLAPFIKHFP---GPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSP-RDFIDAYLLEIEK-QKSNKDSTFQEENLIGSAIDLFFAGTDSTATSIRWGLLFLIQNPDVQE------------------RCHEEIVQVLGYDRLPCMD-DCDRLPYTHATVHEIQRFAKTVPFGVFHETIWPTKLHGFDIPQGTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESYIPFSLGLRACIGESLVRTELFLFATVLLQRIHFSWPPDAKPLD-MDGIVG-IVRYPQTFSIICCSRDSKK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "S4R196-1", "uniprot_id": "S4R196_MOUSE", "id": "S4R196-1", "name": "unspecific monooxygenase", "aln": "---------------------------------MFSLFSGMAFLAGSCLLLKL----ATLCWRRSH--LPPGPFPFPLLGNLWQLNFQLH------------------PNMLFQLA---QTHGSVFTVWLGS-TPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEK---GVICS-NGLTWRQQRRFCLTTLRELGLGKQALEVQLQHEAAELAKVFLQ------EEGRAFDPQIPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALRHLS--GPHQKIFQYHEAVRGFIRHEIIRHKLR-TAEAP-KDFINCYLSQITK-AIDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWALIYLVHHRAIQE------------------RVQQELDEMLGAAQTICYE-DRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGNFVANEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFQFQLPEGSQDLG-LEYVFG-GTLQPQPQKICAVLRQSSLSPREP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZX4-1", "uniprot_id": "D3ZZX4_RAT", "id": "D3ZZX4-1", "name": "unspecific monooxygenase", "aln": "---------------------------------MFSLFGGMAFLAGSFLLLKL----AALCWRRSH--LPPGPFPFPLLGNLWQLNFRLH------------------PNMLFQLA---QTHGNVFTVWLGS-TPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEK---GVICS-NGLTWRQQRRFCLTTLRELGLGKQALELQLQHEAAELAEVFHQ------EQGRAFDPQVPIIRSTTRVIGALVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLYDMFPWALRYLS--GPHQKIFQYHEAVRGFIHHEIIRHKLR-TPEAP-KDFISCYLSQITK-AMDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWAIIYLVHHRAIQE------------------RVQQELDEVLGTAQAVCYE-DRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGYYVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFRFQLPEGSQGLR-LEYVFG-GTLQPQPQKICAVPRLSSLSPREP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K2P4-1", "uniprot_id": "A0A0G2K2P4_RAT", "id": "A0A0G2K2P4-1", "name": "unspecific monooxygenase", "aln": "---------------------------------MVTCEATLLLLLILTLMLMSWGWLAHQARARMQKDLPPGPAPLPLLGNLLQLQSGHL------------------DRVLMELS---SRWGPVFTVWLGP-RPAVVLSGYAALRDALVLQADAFSGRGSMAVFERFTHGN---GIVFS-NGPRWRTLRNFALGALKEFGVGTSTIEERILEETACVLDEFQA------TMGAPFDPRRLLDNAVSNVICTVVFGKRYNYGDPEFLRLLDLFSDNFRIMSSRWGETYNMFPSFMDWIP--GPHHRIFKNFQELRLFISEQIQWHRQSRQTGEP-RDFIDCFLEQMDK-EHQDPESHFQDETLVMTTHNLFFGGTETTSTTLRYGLLIMLKYPEVAA------------------KVQEELDATVGRTRAPSLA-DRAHLPYTNAVLHEIQRFISVLPLGLPRALIRDVNLRNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDQGEFQNNDAFMPFAPGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPADID-LTPQCTGLGNVPPAFQLRLVAR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z7F6-1", "uniprot_id": "D3Z7F6_MOUSE", "id": "D3Z7F6-1", "name": "", "aln": "---------------------------------MVTCLALLLLLLILMLLLW-WGGVVRR-QAQMQKDLPPGPAPLPLLGNLLQLQSGDL------------------DRVLMELS---SHWGPVFTVWLGP-LPAVVLCGYEALRDALVLQADAFSGRGAMAVFDRFTCGN---GIVFS-NGPRWHSLRNFALGVLRELGVGRSTIEDRILEEAACVLDEFQA------TMGAPFDPQQLLDSAVSNVICTVVFGKRYDYGDPEFRRLLNLFSDNFCIMSSRWAEIYNMFPSFMDWIP--GPHNRIFKNFQELRLFISEQIQWHWQSRQTGEP-RDFIDCFLDQMDK-EQQDLESHFQDETLVMTTHDLFFGGTETTSTTLRYGLLIMLKYPEVAA------------------KVQEELDATVGRTWAPRIE-DRARLPYTNAVLHEIQRFISVLPLGLPRALTRDVNLKNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDHGEFQNNDAFMPFALGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPANIN-LNPQCTGLGNVPPAFQLRLVAR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35293-1", "uniprot_id": "CP2F2_RAT", "id": "O35293-1", "name": "Cytochrome P450 2F2", "aln": "---------------------------------MDGVSTAILLLLLAVISLS------LTFTSWGKGQLPPGPKPLPILGNLLQLRSQDL------------------LTSLTKLS---KDYGSVFTVYLGP-RRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGN---GIAFS-DGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLDVLRK------TEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHFINDNFQIMSSPWGEMYNIFPSLLDWVP--GPHRRVFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMVQ-EKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQA------------------RVQEEIDCVVGRSRMPTLE-DRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGEPLARMELFIYLTSILQNFTLHPLVEPEDID-LTPLSSGLGNLPRPFQLCMRIR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00176-1", "uniprot_id": "CP2B1_RAT", "id": "P00176-1", "name": "Cytochrome P450 2B1", "aln": "---------------------------------MEPT--ILLLLALLVGFLL---LLVR-GHPKSRGNFPPGPRPLPLLGNLLQLDRGGL------------------LNSFMQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEY---GVIFA-NGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRK------SQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFP--GAHRQISKNLQEILDYIGHIVEKHRATLDPSAP-RDFIDTYLLRMEK-EKSNHHTEFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAE------------------KVQKEIDQVIGSHRLPTLD-DRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDID-LTPKESGIGKIPPTYQICFSAR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04167-1", "uniprot_id": "CP2B2_RAT", "id": "P04167-1", "name": "Cytochrome P450 2B2", "aln": "---------------------------------MEPS--ILLLLALLVGFLL---LLVR-GHPKSRGNFPPGPRPLPLLGNLLQLDRGGL------------------LNSFMQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEY---GVIFA-NGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRK------SQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFP--GAHRQISKNLQEILDYIGHIVEKHRATLDPSAP-RDFIDTYLLRMEK-EKSNHHTEFHHENLMISLLSLFFAGTETGSTTLRYGFLLMLKYPHVTE------------------KVQKEIDQVIGSHRPPSLD-DRTKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDTFNPEHFLDADGTLKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDID-LTPKESGIAKIPPTYQICFSAR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LT33-1", "uniprot_id": "F1LT33_RAT", "id": "F1LT33-1", "name": "Cytochrome P450", "aln": "---------------------------------MELG--VFLLLTFTVGFLL---LLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGL------------------LRSFMQLQ---EKYGDVFTVHLGP-RPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGY---GVIFA-NGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKK------YKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFP--GVHKQISKNLQEILNYIDHSVEKHRATLDPNTP-RDFIDTYLLHMEK-EKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAE------------------KVQKEIDQVISSHRLPTLD-DRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDID-LTPINSGAGKIPSPYQINFLSRCVG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64583-1", "uniprot_id": "CP2BF_RAT", "id": "Q64583-1", "name": "Cytochrome P450 2B15", "aln": "---------------------------------MELG--VLLLLTFTVGFLL---LLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGL------------------LRSFMQLQ---EKYGDVFTVHLGP-RPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGY---GVIFA-NGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKK------YKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFP--GVHKQISKNLQEILNYIDHSVEKHRATLDPNTP-RDFINTYLLRMEK-EKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAE------------------KVQKEIDQVIGSHRLPTLD-DRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDID-LSPINSGISKIPSPYQIHFLSRCVG-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55071-1", "uniprot_id": "CP2BJ_MOUSE", "id": "O55071-1", "name": "Cytochrome P450 2B19", "aln": "---------------------------------MEFS--VLLLLALTTGFLI---FLVSQSQPKTHGHFPPGPRPLPFLGNLLQMDRRGL------------------LSSFIQLQ---EKYGDVFTVHLGP-RPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGY---GVIFS-SGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKK------YKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFP--GAHRQISKNLQEILDYIGHSVEKHRATLDPSAP-RDFIDTYLLRMEK-EKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAE------------------KVQKEIDQVIGSHRLPTLD-DRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFLDANGALKTNEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLASPVAPENID-LIPNNSGATKTPPQYQIHFLSR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZZ08-1", "uniprot_id": "A0A8I5ZZ08_RAT", "id": "A0A8I5ZZ08-1", "name": "Cytochrome P450", "aln": "---------------------------------MEPS--VLLLLAVLLSFLL---LLVR-GHAKIHGRLPPGPCPVPLLGNLLQMDRRGL------------------LKSFIQLRPIWEKYGDVFTVHLGL-RPVVVLCGTQTIREALVDHAEAFSGRGTIAGLEPVFQDY---GIFFS-SGEQWKTLRRFSMATMRDFGMRKKSVEERIKEESQCLVEELKK------YQGAPLDPTFLFQCITSNIICSIVFGECFDYTDHQFLHLLDLMYQTFSLLSSIFSQVFELFPGVLKYFP--GAHRQISRNLHEILDFIGQSVEKHRATLDPNAP-RDFIYTYLLHMEK--KSNHYTEFHHWNLLSSVLSLFFAGTETSSTTLRYGFLIMLKYPHITE------------------KVQKEIDCVIGSHRLPTLD-DRSKMPYTEAVIHEIQRFSDLAPIGTPHRVIKDTIFRGYLLPKNTEVFPILSSVLHDPQYFEQPDIFNLQHFLDANGALKIIEAFLPFSTGKRICLGESIARNELFLFFTTILQNFSVSSPVAPKDID-LTPKESGIGRIPQVYQICFLAH----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13107-1", "uniprot_id": "CP2B3_RAT", "id": "P13107-1", "name": "Cytochrome P450 2B3", "aln": "---------------------------------MDTS--VLLLLAVLLSFLL---FLVR-GHAKVHGHLPPGPRPLPLLGNLLQMDRGGF------------------RKSFIQLQ---EKHGDVFTVYFGP-RPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPIMQEY---GVSFV-NEERWKILRRLFVATMRDFGIGKQSVEDQIKEEAKCLVEELKN------HQGVSLDPTFLFQCVTGNIICSIVFGERFDYRDRQFLRLLDLLYRTFSLISSFSSQMFEVYSDFLKYFP--GVHREIYKNLKEVLDYIDHSVENHRATLDPNAP-RDFIDTFLLHMEK-EKLNHYTEFHHWNLMISVLFLFLAGTESTSNTLCYGFLLMLKYPHVAE------------------KVQKEIDQVIGSQRVPTLD-DRSKMPYTEAVIHEIQRFSDVSPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALHDPQYFEQPDTFNPEHFLDANGALKKCEAFMPFSIGKRMCLGEGIARSELFLFFTTILQNYSVSSPVDPNTID-MTPKESGLAKVAPVYKICFVAR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20813-1", "uniprot_id": "CP2B6_HUMAN", "id": "P20813-1", "name": "Cytochrome P450 2B6", "aln": "---------------------------------MELS--VLLFLALLTGLLL---LLVQ-RHPNTHDRLPPGPRPLPLLGNLLQMDRRGL------------------LKSFLRFR---EKYGDVFTVHLGP-RPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGY---GVIFA-NGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRK------SKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFP--GAHRQVYKNLQEINAYIGHSVEKHRETLDPSAP-KDLIDTYLLHMEK-EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAE------------------RVYREIEQVIGPHRPPELH-DRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID-LTPQECGVGKIPPTYQIRFLPR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11509-1", "uniprot_id": "CP2A6_HUMAN", "id": "P11509-1", "name": "Cytochrome P450 2A6", "aln": "---------------------------------MLASGMLLVALLVCLTVMV---LMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQM------------------YNSLMKIS---ERYGPVFTIHLGP-RRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGY---GVVFS-NGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRG------TGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLP--GPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSP-RDFIDSFLIRMQE-EEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEA------------------KVHEEIDRVIGKNRQPKFE-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDID-VSPKHVGFATIPRNYTMSFLPR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20853-1", "uniprot_id": "CP2A7_HUMAN", "id": "P20853-1", "name": "Cytochrome P450 2A7", "aln": "---------------------------------MLASGLLLVALLACLTVMV---LMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHI------------------CDSIMKFS---ECYGPVFTIHLGP-RRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGY---GVAFS-NGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRS------THGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQLYEMFSSVMKHLP--GPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSP-QDFIDSFLIHMQE-EEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEA------------------KVHEEIDRVIGKNRQPKFE-DRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDID-VSPKHVVFATIPRNYTMSFLPR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q16696-1", "uniprot_id": "CP2AD_HUMAN", "id": "Q16696-1", "name": "Cytochrome P450 2A13", "aln": "---------------------------------MLASGLLLVTLLACLTVMV---LMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQM------------------YNSLMKIS---ERYGPVFTIHLGP-RRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGY---GVAFS-NGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRG------THGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLP--GPQQQAFKELQGLEDFIAKKVEHNQRTLDPNSP-RDFIDSFLIRMQE-EEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEA------------------KVHEEIDRVIGKNRQPKFE-DRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDID-VSPKHVGFATIPRNYTMSFLPR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15149-1", "uniprot_id": "CP2A2_RAT", "id": "P15149-1", "name": "Cytochrome P450 2A2", "aln": "---------------------------------MLDTGLLLVVILASLSVMF---LVSLWQQ-KIRERLPPGPTPLPFIGNYLQLNMKDV------------------YSSITQLS---ERYGPVFTIHLGP-RRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNILFKGY---GFSLS-NVEQAKRIRRFTIATLRDFGVGKRDVQECILEEAGYLIKTLQG------TCGAPIDPSIYLSKTVSNVINSIVFGNRFDYEDKEFLSLLEMIDEMNIFAASATGQLYDMFHSVMKYLP--GPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSP-RNFIDSFLIRMQE-E-KYVNSEFHMNNLVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPDVEA------------------KVHEEIERVIGRNRQPQYE-DHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPIIGSLMTEPKFFPNHKDFNPQHFLDDKGQLKKNAAFLPFSIGKRFCLGDSLAKMELFLLLTTILQNFRFKFPMNLEDIN-EYPSPIGFTRIIPNYTMSFMPI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10610-1", "uniprot_id": "CP2G1_RAT", "id": "P10610-1", "name": "Cytochrome P450 2G1", "aln": "---------------------------------MALGGAFSIFMTLCLSCLL---ILIAWKRTSRGGKLPPGPTPIPFLGNLLQVRIDAT------------------FQSFLKLQ---KKYGSVFTVYFGP-RPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGY---GLALS-NGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHK------VKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDMYWGVIQYFP--GRHNRLYNLIEELKDFIASRVKINEASFDPSNP-RDFIDCFLIKMYQ-DKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEA------------------KIHEEINQVIGTHRTPRVD-DRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLRSLVPPADID-IAHKISGFGNIPPTYELCFMAR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A820-1", "uniprot_id": "D4A820_RAT", "id": "D4A820-1", "name": "Cytochrome P450", "aln": "---------------------------------MEAASTWALLLALLLLLLA---LTLP--RTPARGQLPPGPTPLPLLGNLLQLRPGAL------------------YSGFLRLS---KKYGPVFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGRGTLATLDKTFDGH---GVFFA-NGERWKQLRKFTLLALRDLGMGKREGEELIQEEVQNLVKAFQR------TEGRPFNPSMLLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLP--GPHTQLQHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQ-EKEDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLKYPQVQK------------------RVREELIQELGPSRTPSLS-DRVRLPYTDAVLHEAQRLLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKHEAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLDTPCPPGDLS-LKPAVRGLFNIPPDFQLQVWPTGDQSR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBX6-1", "uniprot_id": "CP2S1_MOUSE", "id": "Q9DBX6-1", "name": "Cytochrome P450 2S1", "aln": "---------------------------------MEAASTWALLLALLLLLLL---LSLTLFRTPARGYLPPGPTPLPLLGNLLQLRPGAL------------------YSGLLRLS---KKYGPVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTLATLDKTFDGH---GVFFA-NGERWKQLRKFTLLALRDLGMGKREGEELIQAEVQSLVEAFQK------TEGRPFNPSMLLAQATSNVVCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLP--GPHTQLQHHLGTLAAFTIQQVQKHQGRFQTSGPARDVVDAFLLKMAQ-EKQDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLRYPQVQQ------------------RVREELIQELGPGRAPSLS-DRVRLPYTDAVLHEAQRLLALVPMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLDEDGRLRKHEAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLETPCPPGDLS-LKPAISGLFNIPPDFQLRVWPTGDQSR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SQ9-1", "uniprot_id": "CP2S1_HUMAN", "id": "Q96SQ9-1", "name": "Cytochrome P450 2S1", "aln": "---------------------------------MEATGTWALLLALALLLL----LTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGAL------------------YSGLMRLS---KKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGH---GVFFS-NGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQG------TEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLP--GPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQ-EEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQK------------------WVREELNRELGAGQAPSLG-DRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLS-LKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33261-1", "uniprot_id": "CP2CJ_HUMAN", "id": "P33261-1", "name": "Cytochrome P450 2C19", "aln": "---------------------------------MDPF----VVLVLCLSCLL---LLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV------------------SKSLTNLS---KIYGPVFTLYFGL-ERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGF---GIVFS-NGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK------TKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFP--GTHNKLLKNLAFMESDILEKVKEHQESMDINNP-RDFIDCFLIKMEK-EKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTA------------------KVQEEIERVIGRNRSPCMQ-DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD-TTPVVNGFASVPPFYQLCFIPV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11712-1", "uniprot_id": "CP2C9_HUMAN", "id": "P11712-1", "name": "Cytochrome P450 2C9", "aln": "---------------------------------MDSL----VVLVLCLSCLL---LLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI------------------SKSLTNLS---KVYGPVFTLYFGL-KPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGF---GIVFS-NGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRK------TKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFP--GTHNKLLKNVAFMKSYILEKVKEHQESMDMNNP-QDFIDCFLMKMEK-EKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTA------------------KVQEEIERVIGRNRSPCMQ-DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLD-TTPVVNGFASVPPFYQLCFIPV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33260-1", "uniprot_id": "CP2CI_HUMAN", "id": "P33260-1", "name": "Cytochrome P450 2C18", "aln": "---------------------------------MDPA----VALVLCLSCLF---LLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDM------------------SKSLTNFS---KVYGPVFTVYFGL-KPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGL---GILFS-NGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRK------TNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLP--GSHNKIAENFAYIKSYVLERIKEHQESLDMNSA-RDFIDCFLIKMEQ-EKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTA------------------KVQEEIECVVGRNRSPCMQ-DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDID-ITPIANAFGRVPPLYQLCFIPV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10632-1", "uniprot_id": "CP2C8_HUMAN", "id": "P10632-1", "name": "Cytochrome P450 2C8", "aln": "---------------------------------MEPF----VVLVLCLSFML---LFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDI------------------CKSFTNFS---KVYGPVFTVYFGM-NPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGL---GIISS-NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK------TKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP--GTHNKVLKNVALTRSYIREKVKEHQASLDVNNP-RDFIDCFLIKMEQ-EKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTA------------------KVQEEIDHVIGRHRSPCMQ-DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN-TTAVTKGIVSLPPSYQICFIPV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33273-1", "uniprot_id": "CP255_RAT", "id": "P33273-1", "name": "Cytochrome P450 2C55", "aln": "---------------------------------MDPV----LVLVLTLSCLL---LLSLWRQSSGRGKLPPGPTPLPIIGNILQIDVKDI------------------SKSFSYFS---KIYGPVFTLYFGP-KPTVVVHGYEAVKEALDDLGEEFSGRGSFPIVERMNNGL---GLIFS-NGTKWKELRHFSLMTLRNFGMGKRSIEDRIQEEASCLVEELRK------TNGSLCDPTFILSCAPSNVICSVVFHNRFDYKDENFLNLMEKLNENFKILNSPWMQVCNALPAFIDYLP--GSHNRVIKNFAEIKSYILRRVKEHQETLDMDNP-RDFIDCFLIKMEQ-EKHNPRTEFTIESLMATVSDVFVAGSETTSTTLRYGLLLLLKHTEVTA------------------KVQEEIDHVIGRHRRPCMQ-DRTRMPYTDAMVHEIQRYINLIPNNVPHAATCNVRFRNYVIPKGTDLVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSTGKRMCVGEALARMELFLLLTTIVQNFNLKSFVDTKDID-TTPMANTFGRVPPSYQLCFIPR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D816-1", "uniprot_id": "CP255_MOUSE", "id": "Q9D816-1", "name": "Cytochrome P450 2C55", "aln": "---------------------------------MDPV----LVLVLTLSCLL---LLSLWRQNSGRGKLPPGPTPFPIIGNILQIDIKNI------------------SKSFNYFS---KVYGPVFTLYFGS-KPTVVVHGYEAVKEALDDLGEEFSGRGSFQIFERINNDL---GVIFS-NGTKWKELRRFSIMTLRSFGMGKRSIEDRIQEEASCLVEELRK------ANGSLCDPTFILSCAPSNVICSVIFHNRFDYKDEKFLNLMERLNENFKILNSPWMQVYNALPTLINYLP--GSHNKVIKNFTEIKSYILGRVKEHQETLDMDNP-RDFIDCFLIKMEQ-EKHNPHSEFTIESLMATVTDIFVAGTETTNITLRYGLLLLLKHTEVTA------------------KVQAEIDHVIGRHRSPCMQ-DRTRMPYTDAMVHEIQRYIDLIPNNVPHAATCNVRFRSYFIPKGTELVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSIGKRMCVGEALARTELFLILTTILQNFNLKSLVDTKDID-TTPVANTFGRVPPSYQLYFIPR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08683-1", "uniprot_id": "CP2CB_RAT", "id": "P08683-1", "name": "Cytochrome P450 2C11", "aln": "---------------------------------MDPV----LVLVLTLSSLL---LLSLWRQSFGRGKLPPGPTPLPIIGNTLQIYMKDI------------------GQSIKKFS---KVYGPIFTLYLGM-KPFVVLHGYEAVKEALVDLGEEFSGRGSFPVSERVNKGL---GVIFS-NGMQWKEIRRFSIMTLRTFGMGKRTIEDRIQEEAQCLVEELRK------SKGAPFDPTFILGCAPCNVICSIIFQNRFDYKDPTFLNLMHRFNENFRLFSSPWLQVCNTFPAIIDYFP--GSHNQVLKNFFYIKNYVLEKVKEHQESLDKDNP-RDFIDCFLNKMEQ-EKHNPQSEFTLESLVATVTDMFGAGTETTSTTLRYGLLLLLKHVDVTA------------------KVQEEIERVIGRNRSPCMK-DRSQMPYTDAVVHEIQRYIDLVPTNLPHLVTRDIKFRNYFIPKGTNVIVSLSSILHDDKEFPNPEKFDPGHFLDERGNFKKSDYFMPFSAGKRICAGEALARTELFLFFTTILQNFNLKSLVDVKDID-TTPAISGFGHLPPFYEACFIPVQRADSLSSHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20814-1", "uniprot_id": "CP2CD_RAT", "id": "P20814-1", "name": "Cytochrome P450 2C13, male-specific", "aln": "---------------------------------MDPV----VVLLLSLFFLL---FLSLWRPSSGRGKLPPGPTPLPIIGNFFQVDMKDI------------------RQSLTNFS---KTYGPVYTLYVGS-QPTVVLHGYEALKEALVDHGEEFSGRGRLPICEKVAKGQ---GIAFS-HGNVWKATRHFTVKTLRNLGMGKGTIEDKVQEEAKWLVKELKK------TNGSPCDPQFIMGCAPGNVICSIILQNRFDYEDKDFLNLIEKVNEAVKIISSPGIQVFNIFPILLDYCP--GNHNIYFKNHTWLKSYLLEKIKEHEESLDVSNP-RDFIDYFLIERNQ-ENANQWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTA------------------KVQEEIDHVIGRHRSPCMQ-DRSHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFIPFSAGKRMCLGESLARMELFLFLTTILQNFKLKSLVDPKDIN-TTPICSSLSSVPPTFQMRFIPL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24470-1", "uniprot_id": "CP2CN_RAT", "id": "P24470-1", "name": "Cytochrome P450 2C23", "aln": "---------------------------------MELLGFTTLALVVSVTCLS---LLSVWTKLRTRGRLPPGPTPLPIIGNLLQLNLKDI------------------PASLSKLA---KEYGPVYTLYFGT-SPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGY---GLIFS-NGERWKVMRRFSLMTLRNFGMGKRSLEERVQEEARCLVEELQK------TKAQPFDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLP--GKHIEFAKRIDDVKNFILEKVKEHQKSLDPANP-RDYIDCFLSKIEE-EKDNLKSEFHLENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQA------------------KVHEELDRVIGRHQPPSMK-DKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLD-IKPITTGIINLPPPYKLCLVPR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05181-1", "uniprot_id": "CP2E1_HUMAN", "id": "P05181-1", "name": "Cytochrome P450 2E1", "aln": "---------------------------------MSALG-VTVALLVWAAFLL---LVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNI------------------PKSFTRLA---QRFGPVFTLYVGS-QRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDR----GIIFN-NGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRK------TQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP--GSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCP-RDLTDCLLVEMEK-EKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEE------------------KLHEEIDRVIGPSRIPAIK-DRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDID-LSPIHIGFGCIPPRYKLCVIPRS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05182-1", "uniprot_id": "CP2E1_RAT", "id": "P05182-1", "name": "Cytochrome P450 2E1", "aln": "---------------------------------MAVLG-ITIALLVWVATLL---VISIWKQIYNSWNLPPGPFPLPILGNIFQLDLKDI------------------PKSFTKLA---KRFGPVFTLHLGS-RRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNK----GIIFN-NGPTWKDVRRFSLSILRDWGMGKQGNEARIQREAQFLVEELKK------TKGQPFDPTFLIGCAPCNVIADILFNKRFDYNDKKCLRLMSLFNENFYLLSTPWIQLYNNFADYLRYLP--GSHRKIMKNVSEIKQYTLEKAKEHLQSLDINCA-RDVTDCLLIEMEK-EKHSQEPMYTMENVSVTLADLFFAGTETTSTTLRYGLLILMKYPEIEE------------------KLHEEIDRVIGPSRVPAVR-DRLDMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFQGYVIPKGTVVIPTLDSLLYDSHEFPDPEKFKPEHFLNENGKFKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDID-LSPVTVGFGSIPPQFKLCVIPRS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10633-1", "uniprot_id": "CP2D1_RAT", "id": "P10633-1", "name": "Cytochrome P450 2D1", "aln": "---------------------------------MELLNGTGLWSMAIFTVIFILLVDLMHRRHRWTSRYPPGPVPWPVLGNLLQVDLSNM------------------PYSLYKLQ---HRYGDVFSLQKGW-KPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTA------QAGQSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMVKLVEESLTEVSGFIPEVLNTFP-ALLRIP--GLADKVFQGQKTFMALLDNLLAENRTTWDPAQPPRNLTDAFLAEVEK-AKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQR------------------RVQQEIDEVIGQVRCPEMT-DQAHMPYTNAVIHEVQRFGDIAPLNLPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPHRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPVGQPRPS--THGFFAFPVAPLPYQLCAVVREQGL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12939-1", "uniprot_id": "CP2DA_RAT", "id": "P12939-1", "name": "Cytochrome P450 2D10", "aln": "---------------------------------MELLNGTGLWPMAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDPSNM------------------PYSMYKLQ---HRYGDVFSLQMGW-KPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVVFASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTA------QNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVSGFIPEVLNTFP-ALLRIP--GLADKVFQGQKTFMAFLDNLLAENRTTWDPAQPPRNLTDAFLAEVEK-AKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQR------------------RVQQEIDEVIGQVRCPEMT-DQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSVPAGQPRPS--TLGNFAISVAPLPYQLCAAVREQGH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "L7N463-1", "uniprot_id": "L7N463_MOUSE", "id": "L7N463-1", "name": "Cytochrome P450", "aln": "---------------------------------MELLTGTGLWSVAIFTVIFLILVDLMHRRQHWTSRYPPGPVPWPVLGNLLQVDLDNI------------------PYSLYKLQ---NRYGDVFSLQMAW-KPVVVINGLKAMQEVLLTCGKDTADHPPVPIFEYLGFKSKSQGVVLASYGPEWREQRQFSVSTLRNFGLGKKSLEEWVTKEAKHLCDAFTA------RAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPFLIRMLKMREESLKEVTGFIPGVLNTFP-ILLRIP--GLADMVFQSQKTFMAILDNLVTENRTTWDPDQPPRNLADAFLAEIQK-AKGNPESSFNDENLCMVVSDLFTAGMVTTSTTLSCALLLMILHPDVQR------------------RVQQEIDAVIGQVRCPEMA-DQARMPYTNAVIHEVQRFGDIIPLNIPRITSRDIEVQDFLIPKGTILIPNMSSMLKDETVWEKPLRFYPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPAGQPQPS--DHRIFAIPVAPYPYQVCAIMREQGH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087X1C5-1", "uniprot_id": "CP2D7_HUMAN", "id": "A0A087X1C5-1", "name": "Cytochrome P450 2D7", "aln": "------------------------------------MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNT------------------PYCFDQLR---RRFGDVFSLQLAW-TPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFAD------QAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP-VLPHIP--ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEK-AKGSPESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCPIVGTHVCPVRVQQEIDDVIGQVRRPEMG-DQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPS--HSRVVSFLVTPSPYELCAVPR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TAV3-1", "uniprot_id": "CP2W1_HUMAN", "id": "Q8TAV3-1", "name": "Cytochrome P450 2W1", "aln": "---------------------------------MALLLLLFLGLLGLWGLLCACAQDPSP-----AARWPPGPRPLPLVGNLHLLRLSQQ------------------DRSLMELS---ERYGPVFTVHLGR-QKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRG----GGIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDG------YRGRPF-PLALLGWAPSNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFNVYP-WLGALL--QLHRPVLRKIEEVRAILRTLLEARRPHVCPGDPVCSYVDALIQQGQ---GDDPEGLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQG------------------RVQEELDRVLGPGRTPRLE-DQQALPYTSAVLHEVQRFITLLPH-VPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSPASLDTTPARAFTMRPRAQALCAVPRP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "----------------------------------MFYTVIWIFCATLLAILFG--------GVRKPKRFPPGPAWYPIVGSALQVSQLRCRLG-------------MFCKVIDVFARQYVNPYGFYGLKIGK-DKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRL---GVLLT-DGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKN-IDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDE--GNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQE------------------RAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLF-DGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEE---VPLEGATAAVKPYDIMLVAREQ--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.** * :* . . . . :: : * .: :: * : * : : . . . : . . : : :. * : : : : *: :. :* * * : . . : :. : : . : * .:* : .:. * : * * : :::: ::: . ", "identical_positions": 18, "similar_positions": 60, "identity": "3.02%" }, { "cls_id": "homologset.agr.FB:FBgn0001994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJT6-1", "uniprot_id": "D3ZJT6_RAT", "id": "D3ZJT6-1", "name": "", "aln": "------------------------------------------------MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSP---------------------------KRRRAED-----------KDEGIGSPD---------------IWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQHLRTQLLPPP--------------------------------------APTHHPTVIVPAPAPPSSHHINVVTMGPSSVINSVS-------------------------------------------------TSRQNLDTIVQAIQHIEG--------------------------------------------------TQDRQELEEEQRRAVIVKSVRSCPEAHTSDTASDSEASDSDAMDQSREEPLGDGELP-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01664-1", "uniprot_id": "TFAP4_HUMAN", "id": "Q01664-1", "name": "Transcription factor AP-4", "aln": "------------------------------------------------MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSP---------------------------KRRRAED-----------KDEGIGSPD---------------IWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPP--------------------------------------APTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVS-------------------------------------------------TSRQNLDTIVQAIQHIEG--------------------------------------------------TQEKQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V406-1", "uniprot_id": "Q9V406_DROME", "id": "Q9V406-1", "name": "", "aln": "MSAVPVAIKTEEVILEHAEYNSAEELDEELQLQLEDSGGENYHIEFASESAHQGSQRRQSSMSGTNTSKGGGGGGSGALSDGDGSGKPLVDSEKRMRREIANSNERRRMQSINAGFQSLRSLLPRHEGEKLSKAAILQQTFQYIVELENQKTQLLTQNSELKRQVGEHEAGGSGDGGGTNSGGNYNDSNASGGNSTAVAIKKRKLTDNVINIQAISDSSDEGLGSMSPEPMTLLTAGGAAATKLSNAATLLAAKELHESKKQLEKERSLRRLLEDELQMIKRQLYSVATAPPGTAVAAASGGSSGAYIPREVIEHTDNFVRSEDLEELGGTVSYVEIDEMTGQQQVVVCSSIEELEADAAAEIITEDQVHEEVILSSNSSTESENEVNVNAIAKAYAEGCTSSAAMLQPILQAAIKATPKVEVERIHEKIVKVKTEKHDLPSMQTAPHYQHSHRQNLETIVQAIRHLEGDHLFADGSGGQEKFGQQQNLQQHHHQMSGVHHQQLQHHRLAQDAPLALTTTGKQHAALAELRPFLQLKSGGNKQVIITAKTAKDSGGLVSTSTSSTAVTPTAIFKVQTTGGHGNGSHLPAGSSTGTIITGSNGSGGAQQLTITTSLKQCRPGVIVAKQLPSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :: .*:. ..:: ** :*:: : :. *.*:*:***********************::*:*: :************* :**..**::**:** **::*** : * ..... *:*: * .***:** . .: : :*: * ::**:****:* :**:::: :: ::*. . * . .. : :* :*: :: :*:: * .*. .:: . ... ..:.:** ::. : . ...* : ****:******:*:** * .:: * * : :*. . *:.**.** . * : ..: * . :: ", "identical_positions": 112, "similar_positions": 121, "identity": "17.75%" }, { "cls_id": "homologset.agr.FB:FBgn0001995", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCU6-1", "uniprot_id": "RM04_MOUSE", "id": "Q9DCU6-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLRLFQAASRASLRLSGSRVIHSLAEGAERPAEISEPRDSAGLLD-----------PVLRKCELR--IPVHR-RPVQAWVESLRGFEQERIGLAELHPDVFATAPRLDIVHQVAIWQRNFRRISYANTKTRAEVSGGGRKPWQQKGSGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLMQDDLHIVDS------LELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKNVVAATSGLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSRYTPLYPFRLPYSDFP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A131-1", "uniprot_id": "D4A131_RAT", "id": "D4A131-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLRLFQAASRAWLRPNGSRVISSLAEDAVRPAEISEPGDSAGLLD-----------PVLRKCELP--IPAPR-RPVQAWVESLRGFEQERIGLAELHPDVFATTPRLDILHQVAVWQRNFKRISYAKTKTRAEVSGGGRKPWQQKGSGRARHGSIRSPIWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLMQDDLHIVDS------LELPTADPQYLTELAQYRHWGSSVLLVDLTHEEMPKNVMAATSRLNSFNLIPAVGLNVYSMLKHQTLVLTLPSVAFLEDKLLWQDSRYTPLYPFRLPYSDFP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYD3-1", "uniprot_id": "RM04_HUMAN", "id": "Q9BYD3-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLQFVRAGARAWLRPTGSQGLSSLAEEAARATENPEQVASEGLPE-----------PVLRKVELP--VPTHR-RPVQAWVESLRGFEQERVGLADLHPDVFATAPRLDILHQVAMWQKNFKRISYAKTKTRAEVRGGGRKPWPQKGTGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLAQDDLHIMDS------LELPTGDPQYLTELAHYRRWGDSVLLVDLTHEEMPQSIVEATSRLKTFNLIPAVGLNVHSMLKHQTLVLTLPTVAFLEDKLLWQDSRYRPLYPFSLPYSDFPRPLPHATQGPAATPYHC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503X2-1", "uniprot_id": "RM04_DANRE", "id": "Q503X2-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MFRATLAICGRTVVKR--QFISSVSGESALPPNLRLPPNLIGVAAEKRPPPSGSDLPVVRRCEAD--VPAHL-TPAQTWLESLGSRDSDQLGVVDLHPDVFSVPIRLDILHAVEVWQRNFKRISYANVKTRAEVRGGGRKPWQQKRTGRARHGSIRSPLWRGGGIIHGPRGPTSYYYMLPMKVRVQGLKIALSAKLAQDYLHIVDS------LEIPTPDPQYLQDLVKHRQWGDSVLIVDVG-EEFPQNILKATEDLKTVNIIPALGLNVHSLLKHESLVLTLEAVKFLEKKLLWHDVRYTPLYPFKLPYSDLP-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3D0-1", "uniprot_id": "Q9V3D0_DROME", "id": "Q9V3D0-1", "name": "Large ribosomal subunit protein uL4m", "aln": "MLNNILKTSRQVLYPVARTFSRSGNHGNVVTEAAATVGAPPATRS-----------PLILPQDYTDCLPVSRNTARQAWIENTDAVAERKVGLIELHPDVFAAQPRVDIIQENVEWQSKYRYVSMAHTKTRAEVRGGGRKPWPQKGGGRARHGSLRSPMLKGGGVVHGPRSPTTHFYMLPFYKRVLGLTSTLSVKLAQDDLHIIDN------VDIPTGDAEFLKDLIAERNWGPSVLIVDED-HMFPANICQASDDLGYVNLMPTFGLNVYSMLKHDTLVLTVAAVKHLEQRLLYQLNRNDAASKGGKFKLDQV-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51998-1", "uniprot_id": "RL4P_YEAST", "id": "P51998-1", "name": "Large ribosomal subunit protein uL4m", "aln": "----------MTIKRNLVKTLQSIRYQATTATAHAESTLNP--------------------------LPNAAIPPKYALVTVRSFPSLEPLTFVPVPTSTVAAPLRRDILWRAVVYENDNRRVGASNPPGRSENGFSRRKLMPQKGSGRARVGDANSPTRHNGGRALARTAPNDYTTELPSKVYSMAFNNALSHQYKSGKLFVIGGEKVDLISPTPELDLNRLDLVNTNTVEGKEIFEGEVIFRKFLEEFQLKGKRLLFITDKTREGLIKSSDPYKQKVDVIQKELVEVNDILRAQAVFIELEALEYLAMAHQKEILHSVSN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :* . : : : . : ....:. * **: :: . : :. :: *:* . ** ** **** *. .** :.** . .*. : ** .:. :*: : .. *.::.. * * : * : * .:: : . : .. . * .. . ** * ::.: : : ::. * : . ", "identical_positions": 34, "similar_positions": 72, "identity": "10.27%" }, { "cls_id": "homologset.agr.FB:FBgn0002021", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEH2-1", "uniprot_id": "D3ZEH2_RAT", "id": "D3ZEH2-1", "name": "FAD-dependent oxidoreductase domain-containing protein 1", "aln": "MFRKVLRLGLCPGLPTRGLRTRTGGFTLDWDTKVSDFKKKIESILPGKQCEMVYDTSHLPPE----------------------------------QSDVVIIGGGILGLSVAFWLKKLESRRGAMQVLVVEQDHTYSRASSTGPSVGGIWQQFSVPENVQLSLFSINFLRNINEYLAVVDAPPVELRFNPSGCLLLASEKDAATLESNVRMQRQEGAKVCLMSPEQMQNKFPWMNAEGVALASYGLENEGWFDAWSLLQGLRRKVQSMGVFFCQGEVTRFITSSN---QMETPTGEQVVLRRINNVHVKMDKSLEYQPVECAVVVNAAGAWSGQIAELAGIGKGLPGTLQGTKLPVEPRKRYVHLWHCPQG--PGLETPLVADISGVYFRREGLGSNYLGGCSPTEEEEPDPTNLEVDHDFFQNKVWPHLVQRVPSFKTLKVQSAWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGRGLQHAPGIGRAVAEMILEGHFKTIDMSPFLFTRFYLGEKLQEHNIL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TQB2-1", "uniprot_id": "FXRD1_MOUSE", "id": "Q3TQB2-1", "name": "FAD-dependent oxidoreductase domain-containing protein 1", "aln": "MFRRALRLGLGPGLPYRGLRTRKGGFTLDWDAKVSDFKKKVDSILPGKKYEVLYDTSHLPPE----------------------------------QADVVIIGGGILGLSVAFWLKKLESRRGAIRVLVVEQDHTYSRASSTGPSVGGIWQQFSVPENVQLSLFSINFLRNINEYLAVVDAPPVELQFNPSGCLLLASEKDAATLENNVKMQRQEGAKVCLMSPEQLQTKFPWINVEGVALASYGLEDEGWFDAWSLLQGLRRKVQSMGVFFCQGEVTRFITSST---PMKTPTGEHVVLRRINNVHVKMDKSLEYQPVECAVVINAAGAWSGKIAELAGVGKGLPGTLQGTKLPVEPRKRYVHLWHCPQG--PGLETPLVADISGVYFRREGLGSNYLGGCSPTEEEEPDPTNLNVDHDFFQNKVWPHLVQRVPSFKTLEVQSAWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGRGLQHAPGIGRAVAEIMLEGHFKTIDMSPFLFTRFYLGEKLQEYNIL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CU9-1", "uniprot_id": "FXRD1_HUMAN", "id": "Q96CU9-1", "name": "FAD-dependent oxidoreductase domain-containing protein 1", "aln": "MIRRVLPHGMGRGLLTRRPGTRRGGFSLDWDGKVSEIKKKIKSILPGRSCDLLQDTSHLPPE----------------------------------HSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQAS-TGLSVGGICQQFSLPENIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLASEKDAAAMESNVKVQRQEGAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFCQGEVTRFVSSSQ---RMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAGAWSAQIAALAGVGEGPPGTLQGTKLPVEPRKRYVYVWHCPQG--PGLETPLVADTSGAYFRREGLGSNYLGGRSPTEQEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGIGRAVAEMVLKGRFQTIDLSPFLFTRFYLGEKIQENNII--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ10-1", "uniprot_id": "FXRD1_DROME", "id": "Q9VJ10-1", "name": "FAD-dependent oxidoreductase domain-containing protein 1 homolog", "aln": "MLRYRQVVGLLQRRNFSAGATSNGSGSSGGDKSGEDLHPIRRTLRLLGNDMRKVKEFFVPKEPETEKVPIPTQSQFHFSGERDKSKEATVPDDFQTHCDVLIIGGGGVGSSIAYWLK--EKARDGLNVVVVEKDDTYAQSA-TRVSVGGLCQQFSLPENIQMSLFAADFLRSARKHFG----EEVPLQFTPHGHLMLAGEEHAESLKRSSQLQNELGARNELLTADRLTARFPWLNTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGSNEGAYTGLEKAVIQLPDGTRRTCKFALCVISAGASSEQIARLARIGVG-PGILR-VPLPINARKRYMYAINSQAQSAPGMNMPMTIDPSGIFIRRDGLGGNYICVQDSTEEYN----SAMIDPQYFAQHIRPHLYNRIPVLGEAQVVDSWAGCYDHNVYDENGILGAHPYYNNLYLATGFSGHGVQQSLAVGRAISELIMDGQFRTIDLSRLSFDRLIVDQPMFELNNVLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* *: * *. : . * . .::: :: . . .:* * :.**:*:*** :* *:*:*** *. *..:.*:***:*.**:::: * ****: ****:***:*:***: .***. .:::. : *:*.* * *:**.*:.* ::: . ::*.: **: *::.::: :***:*.:*:**.. *:*.****:. .**..:**.... *. * .*:*. * .* : * .. : * . :. : *: : :*** * :** ** :* * ** *: . **::.****:: :. **:: *:. * ** ::**:***.**: ..**: : . :* ::* ::: *** *:* : :* .:*** **:*.:*:**::*.** *:*:******:*:*:: .:***::*:::.*:*:***:* : * *: :.: : * * : ", "identical_positions": 165, "similar_positions": 171, "identity": "31.25%" }, { "cls_id": "homologset.agr.FB:FBgn0002022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q31125-1", "uniprot_id": "S39A7_MOUSE", "id": "Q31125-1", "name": "Zinc transporter SLC39A7", "aln": "--------MTMGLRAPHWVAVGLLTWAALGLLVAGHEGHGDLHKDVEEDFHG--HSHGHSHEDFHHGHSHGHSHEDFHHGHGHTHESIWHGHAHSHDHGHSREELHHGHSHGHSHDSLHHGGHGHAHREHSHGTSREAGAPGIKH-HLDTVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHAPEQP-----------GHGHSH-SGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHG-HSHGHGDRHAHG-DSHTHGDRHECSSKEKPSTEEE-KEVGGLRKRRGGNTGPRDGPVKPQSPEEEKAGSDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLVTAIGALAGTACALLTEGGAVDSDVAGGAGP---GWVLPFTAGGFIYVATVSVLPELLR-EASPLQS------LLEVLGLLGGVAMMVLIAHLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92504-1", "uniprot_id": "S39A7_HUMAN", "id": "Q92504-1", "name": "Zinc transporter SLC39A7", "aln": "--------MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHG--HSHRHSHEDFHHGHSHAH-------GHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDH-EHSHGGYGESGAPGIKQ-DLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQP-----------GHGHSH-SGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHG-HSHGHGHAHSHTRGSHGHG-RQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGP---GWVLPFTAGGFIYVATVSVLPELLR-EASPLQS------LLEVLGLLGGVIMMVLIAHLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUB8-1", "uniprot_id": "S39A7_DANRE", "id": "Q9PUB8-1", "name": "Zinc transporter Slc39a7", "aln": "--------MRVFSKSLLLIAVGILMSQQTLAHSHHHHGHGD------GGCHG--HSHGG--AKMHHGASKWS---------AEANLPHAEEEHHVHDHGHTHNHAHD-HGHAHSHGDIHDHGHAHKH-GHAHDHGAEKSKKVVEAGKRNMVELWMQAIGATLLISAAPFLILFLIPVQSNTDQHQNLLKVLLSFASGGLLGDAFLHLIPHALEPHSHHSQPHSEESHGQSHGEESHGHSHGAAHGHMMSVGLWVLGGIVAFLVVEKFVRLLKGGHS-HSHSH----------------SPSAPKSKDSDEED--DKKGQKKGEKDKVVSQQKPTK----KTVETSSDIKVSGYLNLAADFTHNFTDGLAIGASFLVGPAVGAVTTITILLHEVPHEIGDFAILVQSGCTKRKAMCLQLLTAVGALAGTACSLLAEG-------VGDAAT---AWILPFTAGGFVYIATVTVLPELLAGHSSFWQS------LLEILALLFGVGMMVLIAEYE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3A4-1", "uniprot_id": "CSUP_DROME", "id": "Q9V3A4-1", "name": "Protein catecholamines up", "aln": "MAKQVADYQCSKLQLYQKLALVVILGAVLFSLPALCAGQGNPSFKYSREANENFDPQKAPRAEHHHHHDHDH---------DHGHHHHGHDHDHDHDHGHDHGHHHHGHDHDHDHD------HGHHH--HGHDERHTKAKP-----DLDMSTIWLHSIGSTLLISAAPFVLLYIIPLD-NSEAMKPRLKVLLAFASGGLLGDAFLHLIPHATHPHSHGEHGHDHG---HDHHHHHDGEEHEHGHSHDMSIGLWVLGGIIAFLSVEKLVRILKGGHGGHGHSHGAPKP-----------KPVPAKKKSSDKED--SGDGDKPAKPAKIKSKK--------PEAEPEGEVEISGYLNLAADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAILIKSGCSRRKAMLLQLVTALGALAGTALALLGAGG-------GDGSA---PWVLPFTAGGFIYIATVSVLPELLEESTKLKQS------LKEIFALLTGVALMIVIAKFE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40544-1", "uniprot_id": "YKE4_YEAST", "id": "P40544-1", "name": "Zinc transporter YKE4", "aln": "--------MKASHICSYLLSIAPLVVS--------------------------------------------------------------HGVHHNRDHGHEANHESKQSFLILKQESIFYSLVCFLQ------------------NHLFVLGPRYNAIVAILIIQLMPCLFVLFVPGLRKNDRASLTLSLLVSFSLGTLLGDILLHVIPESLS-----------------------------GVTDVTMVGGAIFLGFISFLTLDKTMRILSGTSN----------------------DDGSIHSHSHSHTP--------------------------QQTAEKKAGFNMSAYLNVISGIAHHITDGIALATSFYSSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNNSHKATSSSANASELMLPFTAGGLIYIATTSVVPQILHSSAPDSKLREFKKWALQLVFIFVGFAVMALMDEH-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : . * :**** . . .: . : . :: : ::*. * ..: ::* :. *.:*::*: * **** :**:**.: . :* :: *:::** ::* :* :.* . . :.: . : ..:*.***: :.::*::***:*:.:*: . :* :*:::: :**:***:******:.** : :*: * :**.**:.**: . .... :*******::*:**.:*:*::* : : ::. :: *. :* :: . ", "identical_positions": 75, "similar_positions": 116, "identity": "14.65%" }, { "cls_id": "homologset.agr.FB:FBgn0002023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q969G2-1", "uniprot_id": "LHX4_HUMAN", "id": "Q969G2-1", "name": "LIM/homeobox protein Lhx4", "aln": "--------------------------------MMQSATVPAEG--------------------------AVKGLPEMLGVP-MQQ---------------------------------IPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDD-------SEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVK---RSRGSSKQEKE---------SSAEDCGVSDSELSF-REDQILSELGHTNRIYGNVGDV-------TGGQLMN----GSFSMDGTG-----QSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIA-HAGQGVSQTLRAMAG--GPTSDISTGSSVG--------YPDFPTSP-----------------------GSWLDEMDHPPF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53776-1", "uniprot_id": "LHX4_MOUSE", "id": "P53776-1", "name": "LIM/homeobox protein Lhx4", "aln": "--------------------------------MMQSAAVPAEG--------------------------AVKGLPEMLGVP-MQQ---------------------------------IPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDD-------SEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVK---RSRGGSKQEKE---------SSAEDCGVSDSELSF-REDQILSELGHTNRIYGNVGDV-------TGGQLMN----GSFSMDGTG-----QSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIA-HAGQGVSQTLRAMAG--GPTSDLSTGSSVG--------YPDFPTSP-----------------------ASWLDEMDHPPF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LZ08-1", "uniprot_id": "F1LZ08_RAT", "id": "F1LZ08-1", "name": "", "aln": "--------------------------------MMQSAAVPAEG--------------------------AVKGLPEMLGVP-MQQ---------------------------------IPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDD-------SEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVK---RSRGGSKQEKE---------SSAEDCGVSDSELSF-REDQILSELGHTNRIYGNVGDV-------TGGQLMN----GSFSMDGTG-----QSYQDLRDGSPYGIPQSPSSISSLPSHAPLLSGLDYTVDSNLGVIA-HPGQGVSQTLRAMAG--GPTSDLSTGSSVG--------YPDFPTSP-----------------------ASWLDEMDHPPF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3V8E3-1", "uniprot_id": "G3V8E3_RAT", "id": "G3V8E3-1", "name": "LIM/homeobox protein Lhx3", "aln": "--------------------------------MLLEAELDCHREQ-----------------------PGAPGAAALCTFSRTPE---------------------------------IPMCAGCDQHILDRFILKALDRHWHSKCLKCSDCHVPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQRE--------AEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMK---RSRGSSKSDKD---------SIQE-GQDSDAEVSF-TDEPSMADMGTANGLYSSLGEP-------APALGRPVGGLGSFTLEHGGLAGP-EQFRELRPGSPYGIPPSPAAPQSLPGPQPLLSSLVYP-DTNLGLVP-SGPPGGPPPMRVLAG-NGPSSDLSTESSGG--------YPDFPASP-----------------------ASWLDEVDHAQF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50481-1", "uniprot_id": "LHX3_MOUSE", "id": "P50481-1", "name": "LIM/homeobox protein Lhx3", "aln": "--------------------------------MLLEAELDCHRER-----------------------PGAPGASALCTFSRTPE---------------------------------IPMCAGCDQHILDRFILKALDRHWHSKCLKCSDCHVPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQRE--------AEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMK---RSRGSSKSDKD---------SIQE-GQDSDAEVSF-TDEPSMADMGPANGLYSSLGEP-------APALGRPVGGLGSFTLDHGGLTGP-EQYRELRPGSPYGIPPSPAAPQSLPGPQPLLSSLVYP-DTNLSLVP-SGPPGGPPPMRVLAG-NGPSSDLSTESSSG--------YPDFPASP-----------------------ASWLDEVDHAQF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBR4-1", "uniprot_id": "LHX3_HUMAN", "id": "Q9UBR4-1", "name": "LIM/homeobox protein Lhx3", "aln": "--------------------------------MLLETGLERDRAR--------------------------PGAAAVCTLGGTRE---------------------------------IPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQRE--------AEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMK---RSRGGSKSDKD---------SVQE-GQDSDAEVSF-PDEPSLAEMGPANGLYGSLGEP-------TQALGRPSGALGNFSLEHGGLAGP-EQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYP-DTSLGLVP-SGAPGGPPPMRVLAG-NGPSSDLSTGSSGG--------YPDFPASP-----------------------ASWLDEVDHAQF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90421-1", "uniprot_id": "LHX3_DANRE", "id": "Q90421-1", "name": "LIM/homeobox protein Lhx3", "aln": "--------------------------------MLLEHPGSS-----------------------------CQNAGNYTRYSSSQD---------------------------------IPVCAGCNQHIVDRFILKVLDRHWHSKCLKCSDCQSQLADKCFSRGDSVYCKDDFFKRFGTKCAACQQGIPPTQVVRRAQDFVYHLHCFACIVCKRQLATGDEYYLMEDSRLVCKADYETAKQRE--------ADSTAKRPRTTITAKQLETLKNAYNNSPKPARHVREQLSTETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMK---RSRGTSKSDKD---------STQEDGMDSDAEVSF-TDEPPMSDLGHSNGIYSSLSES-------SPALSRQGGNHPAFPLEHGAIIPSQEPYHDIQASSPYSLPQSPGPLQPLPRHQPLISSLVYP-ESGLPMAGQSGGQDMTPGVRMMAAGNGPSSDLSTGSSGG--------YPDFPASP-----------------------ASWLDEVDHAQF----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PD53-1", "uniprot_id": "M9PD53_DROME", "id": "M9PD53-1", "name": "", "aln": "MMQTLKPPPPLHHHHQHQHQLQHPPQQQPHPHQQLQHPLQQQQHLSAMDNHQQHQPHIHQQQQQQQQLPPTPQASHLVGGQQQQQQHPHHNHLAVDQDDPNPELVLALISRNRALEATIPKCGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDMGIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAKAKGLYLDGSLDGDQPNKRPRTTITAKQLETLKTAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRLKKDAGRTRWSQYFRSMKGNCSPRTDKFLDKDELKVDYDSFSHHDLSNDSYSTVNLGLDEGASPHSIRGSYMHGSSSPSQYPPSSRSPPPVGQGHTFGSYPDNIVYTNIDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDFPPSPDSWLG-DSGSTNTTSANNNANNNSSSSHNNNNSSGGGSGGVSVSTAPNPSAPGVHYXYSNLLLRYFEMQSRSLLLAAAQQQQQHQPHSSQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ** *.**.: *:*:****.*:* **:.**:*::*: * ::**:* .::**:*****:****:**: *********:*** ****:** * :*.* * ****:***** :*:** *** ** . .: ****************.**:.************* :**************************** **.*:::.:* .* . :*: * : * : :.: :: .. . ::.. . : :. : .:: ...: *. . *. . .. : . . * ..:*. .. ** * . *::* .: :: :* . ", "identical_positions": 152, "similar_positions": 99, "identity": "27.34%" }, { "cls_id": "homologset.agr.FB:FBgn0002031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P67778-1", "uniprot_id": "PHB1_MOUSE", "id": "P67778-1", "name": "Prohibitin 1", "aln": "--MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEG--THFLIPW----VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAG-------------QSVLLQLPQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P67779-1", "uniprot_id": "PHB1_RAT", "id": "P67779-1", "name": "Prohibitin 1", "aln": "--MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEG--THFLIPW----VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAG-------------QSVLLQLPQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35232-1", "uniprot_id": "PHB1_HUMAN", "id": "P35232-1", "name": "Prohibitin 1", "aln": "--MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEG--THFLIPW----VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAG-------------QSVLLQLPQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZUY9-1", "uniprot_id": "A0A8I5ZUY9_RAT", "id": "A0A8I5ZUY9-1", "name": "Prohibitin", "aln": "--MAAKVFESIGKFGLALAVAGGVVNSALYNVDAAT-----DRFRGVQDIVVGEG--THFLIPW----VQKPIIFDCRSRPRKVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNIT-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58IDC6-1", "uniprot_id": "A0AC58IDC6_DANRE", "id": "A0AC58IDC6-1", "name": "Prohibitin", "aln": "---MAKLFESIGKLGLALAIGGGVVNSALYNVDAGHRAVIFDRFRGVQDVVVGEG--THFLIPW----VQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVAGQLPRIFTSIGEDYDERVLPSITTEVLKSVVARFDAGELITQRELVSRQVSEDLTERASTFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFVVEKAEQQKQAAIISAEGDSQAALLIANSLAEAGDGLVELRKLEAAEDIAFQLSRARNVTYLPSG-------------QGTLLQLPQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0M6C3-1", "uniprot_id": "A0ABK0M6C3_RAT", "id": "A0ABK0M6C3-1", "name": "Prohibitin", "aln": "--MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACT-RVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVR----QSMFLRLPQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24156-1", "uniprot_id": "PHB1_DROME", "id": "P24156-1", "name": "Prohibitin 1", "aln": "--MAAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEG--THFFIPW----VQRPIIFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSG-------------QSTLLNLPSTIAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40961-1", "uniprot_id": "PHB1_YEAST", "id": "P40961-1", "name": "Prohibitin-1", "aln": "MSNSAKLIDVITKVALPIGIIASGIQYSMYDVKGGSRGVIFDRINGVKQQVVGEG--THFLVPW----LQKAIIYDVRTKPKSIATNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLGLDYDERVLPSIGNEVLKSIVAQFDAAELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTFGPEFTKAVEQKQIAQQDAERAKFLVEKAEQERQASVIRAEGEAESAEFISKALAKVGDGLLLIRRLEASKDIAQTLANSSNVVYLPSQHSGGGNSESSGSPNSLLLNIGR----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. ...: :. .. : ... . : .. ** .*: .: :::.:*:* *::*:.:.. **:**** *.:***:*.** *** *: :* ** ******* *:**::**:*:* *******::*::: .:*: ** **: *:*:*:**:*** *** *** **:***:** *:*:*****::: *::* ***::::* ::::::. .****: :*::**::*** *: : .:. ", "identical_positions": 99, "similar_positions": 93, "identity": "33.33%" }, { "cls_id": "homologset.agr.FB:FBgn0002036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99K82-1", "uniprot_id": "SMOX_MOUSE", "id": "Q99K82-1", "name": "Spermine oxidase", "aln": "--------------MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVR-LGDTTFELGATWIHG-SHGNPIYQLAEANGLLEETTDGERS----VGRISLYSKNGVACYLTNRGCRIPKDVVEEFSDLYNEVYNMTQEFFRHGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKVESCESSSHSIDEVSLSAFGEW-TEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIHWDQASAHPRGPEIEPRGEGDHNHDTGEGGQSGENPQQGRWDEDEPWPVVVECEDCEVIPADHVIVTVSLGVLKRQYT--------SFFRPCLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESCTLTYPPEL---------------------WYRKICGFDVLYPPERYGHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTG------------------NPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWM0-1", "uniprot_id": "SMOX_HUMAN", "id": "Q9NWM0-1", "name": "Spermine oxidase", "aln": "--------------MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGGRVQSVK-LGHATFELGATWIHG-SHGNPIYHLAEANGLLEETTDGERS----VGRISLYSKNGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEW-TEIPGAHHIIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEPRGGRWDEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYT--------SFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESHTLTYPPEL---------------------WYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTG------------------NPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JJQ4-1", "uniprot_id": "B8JJQ4_DANRE", "id": "B8JJQ4-1", "name": "", "aln": "--------------MDSMAQRPD-----------RDSQ--IFIIGCGISGIGAAQKLIKHGFHNVRIIEATARSGGRIRTGR-LGDNIIEIGANWIHGPSKENPVFRLACDYQLLDKESMSEENQAIDIGGHPLFVPN----WFTSSGRKLGPETMGPALEFFMTLLERSQQFHSTG----GEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVSGTHTMDDVGLGAFGMY-TTLPGLDCTFPGGYEGLTDHMMKELPRDIVLYNKPVKCIHWNYTKNGP-----------------NTGGTS--------------FPVTIECVNGETFAADHVIVTVPLGYMKKHQN--------TFLSPSFPLHKLHSIQRMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMS--------------------WIRKLTGFTVLKPTERFGHVLCGWIAGQESEYMESLSELEVLQTVTQLLRIFTG------------------NPTI-MPRKLLRSQWFHEPYSCGSYSYVAKGCSGYDIDNLAEPLPLK-GSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAERLISHHTSASGSFSSKL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NH10-1", "uniprot_id": "A0A8M1NH10_DANRE", "id": "A0A8M1NH10-1", "name": "Amine oxidase", "aln": "---------------------------------MVDRSPSIVVVGAGVAGLAAAKKLKEYGFNDVTVLEAAENVGGRVATAT-LGNACVDTGAQYIHGTSEKNPVYCLLKG-LLNQLPEMGEEA------------------FYNNKGHKVNANFARRAYEHGESFIYHRG---------SGNSGKSLGEHYAVKTQGVIERLQEDEKARMQSVFALVGKDMLIDIGAS---DLHRISLDSWQYY-IDMG-DSVNITGFMYQLVDLLKEDFPKDRLLLKREVRTIKWDGSFPSPQ----------------NEASPEGK---------VRQYPVCIVCEDGEEILADHVIVTVSLGCLKAQAS--------DLFIPSLPTEKIEVINKLCFGNIAKIFLAYEEAFWENDVGSISFIYEDDTPASISTN--KMQ--------------------WLKSMQSFSVLRPKERFGNVLIGWCPGEIADLVETMTDNELSAAVTDHLKMFFGP-----------------SANIPQPKSILCTKWRSNKFIKGSYTFLPVGVDGQVMDTLAQPLEGS-QFPDAHLQVMFAGEATMKTLYGTVQGALLSGHREADRLAAHYKDAVASTSASMDKHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18487-1", "uniprot_id": "A37C_DROME", "id": "P18487-1", "name": "Protein anon-37Cs", "aln": "MQCFKLASRRSLYNARVLQADNIGDKQRSPDLEAARQNTQIVVVGAGLAGLSAAQHLLSHGFRRTVILEATDRYGGRINTQR-FGDTYCELGAKWVKIDGSQDSMYELLRNTEGLGKQIKQPDR-----------------ATYLQDGSRINPAMVELIDTLFRQLCRGFKVSERVKTGGDLHSLDNVMNYFRTESDRIIGVSFQHPKD--QLAAREIFQSLFKEFGSILGCCLEYVNIEHITKCPVQQEQRPLYVPTGLDNVVDDLIQNMDKAQLQTGKPVGQIQWTPAPMKS-----------------------------------------VGCLDGSLYNADHIICTLPLGVLKSFAG--------VLFRPTLPLDKMLAIRNLGFGNPLKIYLSYKKPIGRWLKGSLRPLGTLLNPSVEQQP--ERN--------------------WTQQVVEISQVPSSQ---HVLEVHVGGGYYEEIEKLPDEELLEQITGLLRRCVS------------------SHLVPYPQELLRSNWSTSACYLGGRPYFSTNSSARDVQRLAAPLGEK------SPGLLFAGDATSLRGFGTIDAARSSGIREAQRIIDYYLKSVHCG--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50264-1", "uniprot_id": "FMS1_YEAST", "id": "P50264-1", "name": "Polyamine oxidase FMS1", "aln": "------------------------------MNTVSPAKKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHHD-TLTNPLFLEEAQLSLNDGRTRFVFD-------------DDNFIYIDEERGRVDHDKELLLEIVDNEMSKFAELEFH------QHLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRN---------AFALNYDSVVQRIAQSFPQNWLKLSCEVKSITREPSKNVT-----------------------------------------VNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLKPVIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSMLEREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPGDDPVDMVVAMSNGQDS--------RIRFAGEHTIMDGAGCAYGAWESGRREATRISDLLK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.::*.*::*: ** * . *: ::** . ***: : : ** : : :.:: . :: . . . . . . . : .. :.: : : : : * * : . : * : **::* *:. . :: : * : : .: :* *: . ::: : : : * : : . . :: . : *. . : :: : * . *. . . . : . : *:*: * . .* ** *** *: ", "identical_positions": 38, "similar_positions": 95, "identity": "6.03%" }, { "cls_id": "homologset.agr.FB:FBgn0002044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4J7-1", "uniprot_id": "A0ABK0L4J7_RAT", "id": "A0ABK0L4J7-1", "name": "RNA-binding protein 27", "aln": "----MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGFVDKLFESLYTKNYLPPLEPVKPEPKP----LVQEKEEIKEEVFQEPAEEERDVRKKKYPSPQKSRSESSERRTREKKREDGKWR--DYERYYERNELYREKYDWRRGRSKSRSKSRGLSRSRSRSRGRSKDR-------------DPNRNVEHRERS----KFKSERND-LESS----YVPVSAPPPNSSEQYSSGAQSIPSTVTVIAPAHHSENTTESWSNYYNNHSSSNSFGRNPPPKRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEVALPSMIPFPPPP-PGLPPPPPPGMLMPPMPGPGPGPG--------------HSMRLPVPQGHGQPPPSVVLPIPRPPISQSSLINSRDQPGTSAVPNLAPVG---------ARLPPPLPQNLLYTVSERQPMYSREHGAAASERLQLGTPPPLLAARLVPPRNLMGSSIGYHTSVSSPTPLVP-----DTYEPDGYNPEAPSITSSGRSQYRQFFSRAQTQRPNLIGLTSGDMDANPRAANIVIQTEPPVPVSINSNITRVVLEPESRKRAIS-GLEGPLTKKPWLGKQGNNNQSKPGFLRKNQYT--NTKLEVKKIPQELNNITKLNEHFSKFGTIVNIQVAFKGDPEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPALQSSAQILLQQQHTLSHLSQQHHNLPQHLHPQQVMVTQSSPSSVHGGIQKMMGKPQTSGAYVLNKVPVKHRLGHATTNQSDTSHLLNQTGGSSGDDCPVFSTPGHPKTIYSSSNLKAPSKLCSGS-KSHDVQEVLKKKQEAMKLQQDMRKKRQEMLEKQIECQKMLISKLEKNKNMKPEERANIMKTLKELGEKISQLKDELK-----------TSSAVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDTTELRKKLSQLQVEAARLGILPVGRGKTMSSQGR----GRGRGRG-RGRGSLNHMVVDHRPKALPAGGFIEEEKEELLQHFS-----------------------------ATNQSSKFKDRRLQISWHKPKVPSISTETEEEEV---------------------KEEETETS---DLFLHDDDDEDEDEYESRSWRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SFM8-1", "uniprot_id": "RBM27_MOUSE", "id": "Q5SFM8-1", "name": "RNA-binding protein 27", "aln": "----MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGFVDKLFESLYTKNYLPPLEPVKPEPKP----LVQEKEEIKEEVFQEPAEEERDTRKKKYPSPQKSRSESSERRTREKKREDGKWR--DYERYYERNELYREKYDWRRGRSKSRSKSRGLSRSRSRSRGRSKDR-------------DPNRNVEHRERS----KFKSERND-LESS----YVPVSAPPPSSSEQYSSGAQSIPSTVTVIAPAHHSENTTESWSNYYNNHSSSNSFGRNPPPKRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEVALPSMIPFPPPP-PGLPPPPPPGMLMPPMPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLPIPRPPISQSSLINSRDQPGTSAVPNLAPVG---------ARLPPPLPQNLLYTVSERQPMYSREHGAAASERLQLGTPPPLLAARLVPPRNLMGSSIGYHTSVSSPTPLVP-----DTYEPDGYNPEAPSITSSGRSQYRQFFSRAQTQRPNLIGLTSGDMDANPRAANIVIQTEPPVPVSVNSNVTRVVLEPESRKRAIS-GLEGPLTKKPWLGKQGNNNQSKPGFLRKNHYT--NTKLEVKKIPQELNNITKLNEHFSKFGTIVNIQVAFKGDPEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPALQSSAQILLQQQHTLSHLSQQHHSLPQHLHPQQVMVTQSSPSSVHGGIQKMMGKPQTSGAYVLNKVPVKHRLGHASTNQSDTSHLLNQTGGSSGEDCPVFSTPGHPKTIYSSSNLKAPSKLCSGS-KSHDVQEVLKKKQEAMKLQQDMRKKKQEMLEKQIECQKMLISKLEKNKNMKPEERANIMKTLKELGEKISQLKDELK-----------TSSTVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDTTELRKKLSQLQVEAARLGILPVGRGKTISSQGR----GRGRGRG-RGRGSLNHMVVDHRPKALPGGGFIEEEKDELLQHFS-----------------------------ATNQASKFKDRRLQISWHKPKVPSISTETEEEEV---------------------KEEETETS---DLFLHDDDDEDEDEYESRSWRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2N5-1", "uniprot_id": "RBM27_HUMAN", "id": "Q9P2N5-1", "name": "RNA-binding protein 27", "aln": "----MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGFVDKLFESLYTKNYLPLLEPVKPEPKP----LVQEKEEIKEEVFQEPAEEERDGRKKKYPSPQKTRSESSERRTREKKREDGKWR--DYDRYYERNELYREKYDWRRGRSKSRSKSRGLSRSRSRSRGRSKDR-------------DPNRNVEHRERS----KFKSERND-LESS----YVPVSAPPPNSSEQYSSGAQSIPSTVTVIAPAHHSENTTESWSNYYNNHSSSNSFGRNLPPKRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEVALPSMIPFPPPP-PGLPPPPPPGMLMPPMPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLPIPRPPITQSSLINSRDQPGTSAVPNLASVG---------TRLPPPLPQNLLYTVSERQPMYSREHGAAASERLQLGTPPPLLAARLVPPRNLMGSSIGYHTSVSSPTPLVP-----DTYEPDGYNPEAPSITSSGRSQYRQFFSRTQTQRPNLIGLTSGDMDVNPRAANIVIQTEPPVPVSINSNITRVVLEPDSRKRAMS-GLEGPLTKKPWLGKQGNNNQNKPGFLRKNQYT--NTKLEVKKIPQELNNITKLNEHFSKFGTIVNIQVAFKGDPEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPTLQSSAQLLLQQQQTLSHLSQQHHHLPQHLHQQQVLVAQSAPSTVHGGIQKMMSKPQTSGAYVLNKVPVKHRLGHAGGNQSDASHLLNQSGG-AGEDCQIFSTPGHPKMIYSSSNLKTPSKLCSGS-KSHDVQEVLKKKQEAMKLQQDMRKKRQEVLEKQIECQKMLISKLEKNKNMKPEERANIMKTLKELGEKISQLKDELK-----------TSSAVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDTTELRKKLSQLQVEAARLGILPVGRGKTMSSQGR----GRGRGRGGRGRGSLNHMVVDHRPKALTVGGFIEEEKEDLLQHFS-----------------------------TANQGPKFKDRRLQISWHKPKVPSISTETEEEEV---------------------KEEETETS---DLFLPDDDDEDEDEYESRSWRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRC3-1", "uniprot_id": "D3ZRC3_RAT", "id": "D3ZRC3-1", "name": "RNA-binding protein 26", "aln": "MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVDFLQHQEKDIKKEE-LTKEEEREKKFSRRLNHSPPQSSSRYRDNRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRDRDRDR----------SRTRSRSRTRSRERDLVKPKYDLDRTDPLENN----YTPVSSVSNISSGHYP--VPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQP-PVVEGPPPPGLPPPPP---------------------------------ILTPPPVNLRPPVPP------------PGP-LPPSLPPVTDDISYSLVLTGPPPPLPP-------------LQPSGMDA---------PPNSATSSVP--TVVTTGIHHQPPPAPPSLFTA-----DTYDTDGYNPEAPSITNTSRPMYR---HRVHAQRPNLIGLTSGDMDLPPREK------------PPNKSSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYDEAKKAISSTEAVLNNRFIKVYWHREGA-THQLQTTSPKVIQPLVQQPILPVVKQSVKERLGPVPSGTVEPAEA----------QSATSELPQNVTKLSVKDRLGFV------------SKPSVSATEKVLSTSTGLTKTVYNPAALKAAQKTLLVSTPAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEILTKNITKLKDEVKS----------TSPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGAAHGRGRG-RGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAIITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVANMSAVETEEAEP---------------------DEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZN0-1", "uniprot_id": "RBM26_MOUSE", "id": "Q6NZN0-1", "name": "RNA-binding protein 26", "aln": "MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVDFLQHQEKDIKKEE-LTKEEEREKKFSRRLNHSPPQSSSRYRDNRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRDRDRDR----------SRTRSRSRTRSRERDLVKPKYDLDRTDPLENN----YTPVSSVSNISSGHYP--VPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQP-PVVEGPPPPGLPPPPP---------------------------------ILTPPPVNLRPPVPP------------PGP-LPPSLPPVT----------GPPPPLPP-------------LQPSGMDA---------PPNSATSSVP--TVVTTGIHHQPPPAPPSLFTAVFVLPDTYDTDGYNPEAPSITNTSRPMYR---HRVHAQRPNLIGLTSGDMDLPPREK------------PPNKSSMRIVVDSESRKRTIGSGEPGVSTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGT-TQQLQTTSPKVIQPLVQQPILPVVKQSVKERLGPVPSATTEPAEA----------QSATSELPQNVTKLSVKDRLGFV------------SKPSVSATEKVLSTSTGLTKTVYNPAALKAAQKTLSVSTPAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEILTKNITKLKDEVKS----------TSPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGTAHGRGRG-RGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDASLHAIITFKTRAEAEAAAIHGARFKGQDLKLAWNKPIANMSAVDTEEAEP---------------------DEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T8P6-1", "uniprot_id": "RBM26_HUMAN", "id": "Q5T8P6-1", "name": "RNA-binding protein 26", "aln": "MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEE-ITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDR----------SRTRSRSRTRSRERDLVKPKYDLDRTDPLENN----YTPVSSVPSISSGHYP--VPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQP-PVVEGPPPPGLPPPPP---------------------------------ILTPPPVNLRPPVPP------------PGP-LPPSLPPVT----------GPPPPLPP-------------LQPSGMDA---------PPNSATSSVP--TVVTTGIHHQPPPAPPSLFTA-----DTYDTDGYNPEAPSITNTSRPMYR---HRVHAQRPNLIGLTSGDMDLPPREK------------PPNKSSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGS-TQQLQTTSPKVMQPLVQQPILPVVKQSVKERLGPVPSSTIEPAEA----------QSASSDLPQNVTKLSVKDRLGFV------------SKPSVSATEKVLSTSTGLTKTVYNPAALKAAQKTLLVSTSAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEVLTKNITKLKDEVKA----------ASPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHSRGRGAVHGRGRG-RGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVTNISAVETEEVEP---------------------DEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7L9-1", "uniprot_id": "A0ACD6B7L9_DANRE", "id": "A0ACD6B7L9-1", "name": "", "aln": "----MIIENLEALKTWLSKTLEPICDADPSALAKYVVALVKKDKSEKELKALCIDQLDVFLQKETQTFVDKLFEAVNAKSYLPQPEQPTPASRPETHQRTEKDEAKREEPPSRDEDREKKFSRRINHSPPSSSRYSRDSRRVDDRKKDDRSRKREYDRNPPRRDSYRERYNRRRERSRSYSRSRSRSWSKDRTRDRDRERDRDRDRSRSRSRTRSRSRSRSRERDSGKPKYEHSRPERPEGATTDGYTAAPLPPVNSSAHFP--VPTLSSTITVIAPTHHGNNTTESWSEFPQD---HTPFGRGGPPRKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPSILPFQPPPLPGVDGPPPPGLPPPHA---------------------------------LLTPP-VNLRPPVPP------------PGT-MPPSLPPVA----------GPPPPLPA-------------LQPSGMDG---------PPNSITSSVP--TIVTSGIRPPMTQPPPPLFTS-----DPFEPDVYNPEAPSMT--SRPMYR---HRVNAQRPNLIGLTMAEMDLPPREK------------MSNSNNARIVLESDSRKRGAGLHDLAIPPKKPWFDKPNFSKPNHHGFHRKVPFPLANTKLAIGQIPPELNNISKLNQHFSKFGTIVNLQVAYNNDPEGALIQFATPEEARRAIQSTEAVLNNRFIRVHWHREDT-VEHMHPKPHPSVQP-AQEPAVTALKQSVKDRLGPLPTPHPEPTPA----------PSGP---PQNTLKASVKERLGFS------------KPPGLGT--KVLSTSTGLTKTVYNPAALKAGQKGAPFS-ASVSAEDALKRKQEAMKLQQDVRKKKQEILEKHIQTQKLLISRLEKNKSMKAEDKAQIMQTLTSLTNSITKLQEEIKG----------LSSANALRTTVKSKAQAQKELLDTELDLYKKMQAGEDTAELKIKYTQLQLEAAKRGLLTPGRGRGAHSRGRGALRSRGRGIRGRGRGAPTHAVVDHRPRALEISGFSEADRVDLLPHFAQYGEIEDCQMEDSSLSAIITYKTRAEAEQAAIHGVRLNNQELRLAWHKPTASLNTTDPDEAEA---------------------EDEEFPEDSLVDDSLLQDDDEEEEDNESRSWRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIV2-1", "uniprot_id": "SWM_DROME", "id": "Q9VIV2-1", "name": "Zinc finger protein swm", "aln": "----MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFVERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNVIKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDHKTKDSHNQQSASNYQHHHVR----------SASPPGRSSGVSGSGGGGPGGAGLAAGYADKE----NQPRDSRRRRASLRSRSRSRSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAP---------------------------------VAPPAPVEHPASHPRQRCRDFDEKGYCVRGETCPWDHGVN------------PVVFEG-------------INNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGNVRPTTLMSGSGPSPMGVPNPADYARNPGAPPQAAMMPFPFNPTAVTTPLQRQLIP-----------IPVVDGAPTGGVAEVGKRRFELEDTVAIADVPTKRKVPIN--SRLGPRVNPNMQQHNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRFIKVFWHNDSS------GADVGQMNQMGGGGGGGGRKNASQYHLHNVPAVPTPNADG----------AKISNANPLTEAGAGNIGTPATEQAN--------TAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDPQ-RAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAIQKRLEELQRN---LGVGSAANNKSTHYAPASGAPGGGAG-RKRPNLPEGPTRVDRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISWAPVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::*: : ** **: ***:****.****.**:**:****.:*:** : :******.:** **::**::: ::.**. . .: : * .* . : . . .: . * : :. : : . . . . . . : : * . . : . :* : : .. :. . :.....* . : . : :: *::*.: : .* .... .. :. . .. . * .*. * . * * * * : . . * * : .. . . .*.. .:. . . : * :. * : . .: ** .. . * . . * : *:.* : ::* **.*::**:**::**.:**:**:::.***.*:: : * **. * ***********:* **.:. :: :: :* : . . . . . :: * . ... : : : :. :::: . :* :.:**::**:*:. :: * :. :*: . ..: :* ::*: * .* :*:.*:* . *:* : :***** **:* : . *::.: :: : :** : *: . ...: . * * * . **:**:*: .* : :* ** :. :. :.: *:::* . : . * .:.* * :*:*:::: *.*****", "identical_positions": 161, "similar_positions": 260, "identity": "13.64%" }, { "cls_id": "homologset.agr.FB:FBgn0002121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4K5-1", "uniprot_id": "L2GL1_RAT", "id": "Q8K4K5-1", "name": "Lethal(2) giant larvae protein homolog 1", "aln": "---------MMKFRFRR-QGADP----------------------------------QREKLKQELFTFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAA------TVTQMHFLPGQGRLLTLLDDSSLHLWEIIQRNGCAHLEEGLSFHPPSRPSFGNASFPAGLTRVTVVLLAAG-DTVVLGTESGSIFFLDVATLALLEGQTLSPDEVLRSVPDDYRCGKALGPVESLQGHLQDPSKILIGYSRGLLVIWSQATQSVEHVFLGNQQ-----------------LESLCWGR--GGSNIISSHSDGSYAIWSTDTGSPPTLQPTVVTTPYGPFPCKAINKILWRSCESGDHFIIFSGGMPRASYGDRHCVSVLRAE-TLVTLDFTSRVIDFFTVHSTQPEDGFDNPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPSKLWARIVSAGERQSPQPASSALSWPITGG---RNLAQ-----EPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEH-----ADSLAQAVEDDWPPFRKVGCFDPYSDDPRLGIQKVALCKYTAQMVVAGTAGQVLVLELSD---VPGEHTVSVASVDLLQDREGFTWKGHERLSPHTGPLP------WPAGFQPRVLIQCLPPAAVTAVALHAEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRATTAS--SKLQEANAQLAEQTCPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDATHHGPTMWAGTNSGSVFAYALEVPAATAGGEKRPEQA----------VEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVMSED-------------------------------------YAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDISWPQNATQP----RLQESPKLSQANGTRDIILAPESCEGSPSSAHSKRADTMEPPEAALSPVSIDS-AASGDTMLDTTGDVTVEYVKDFLG----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y17-1", "uniprot_id": "L2GL1_MOUSE", "id": "Q80Y17-1", "name": "Lethal(2) giant larvae protein homolog 1", "aln": "---------MMKFRFRR-QGADP----------------------------------QREKLKQELFAFHKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAA------TVTQMHFLPGQGRLLTLLDDSSLHLWEIIHHNGCAHLEEGLSFHPPSRPSFDNASFPASLTRVTVVLLVAG-NTAALGTESGSIFFLDVATLALLEGQTLSPDVVLRSVPDDYRCGKALGPVESLQGHLQDPSKILIGYSRGLLVIWSQATQSVDNVFLGNQQ-----------------LESLCWGR--DGSSIISSHSDGSYAIWSTDTGSPPTLQPTVVTTPYGPFPCKAINKILWRSCESGDHFIIFSGGMPRASYGDRHCVSVLRAE-TLVTLDFTSRVIDFFTVHSTQPEDECDNPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVANVPSKLWARIVSAGEQQSPQPASSALSWPITGG---RNLAQ-----EPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEH-----ADSLAQAVEDDWPPFRKVGCFDPYSDDPRLGIQKVALCKYTAQMVVAGTAGQVLVLELSE---VPAEHAVSVANVDLLQDREGFTWKGHERLNPHTGLLP------WPAGFQPRMLIQCLPPAAVTAVTLHAEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRTPAAS--SKLQEANAQLAEQTCPHDLEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDATHHGPTMWAGTNSGSVFAYALEVPAATAGGEKRPEQA----------VEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVMSED-------------------------------------YAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDISWPQNATQP----RLQESPKLSQANGTRDIILAPESCEGSPSSAHSKRADTMEPPEAALSPVSIDS-AASGDTMLDTTGDVTVEYVKDFLG----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15334-1", "uniprot_id": "L2GL1_HUMAN", "id": "Q15334-1", "name": "Lethal(2) giant larvae protein homolog 1", "aln": "---------MMKFRFRR-QGADP----------------------------------QREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAA------TVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPLSLTRVTVVLLVAASDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQ-----------------LESLCWGR--DSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGHFIIFSGGMPRASYGDRHCVSVLRAE-TLVTLDFTSRIIDFFTVHSTRPEDEFDDPQALAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGG---RNLAQ-----EPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQTDCEH-----ADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLVLELSD---VPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLP------WPAGFQPRVLVQCLPPAAVTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRAANAS--SKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLSGVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQA----------VEAVLGKEVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPKVSAKTKFKLTAHEGCRVRKVALATFASVACED-------------------------------------YAETCLACLTNLGDVHVFSVPGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQAS--YRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDS-ATSADTTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBF6-1", "uniprot_id": "A0A8M2BBF6_DANRE", "id": "A0A8M2BBF6-1", "name": "", "aln": "---------MMKFRFRR-QGNDP----------------------------------HREKIKQDLFAFNKTVEHGFPNQPSALAYDPKLQLMAIGTKSGAIKIYGAPGVEMTGLHKDTA------AVTQIHFLCGQGRILSLLDDNTIHLWEIVQRENRSHLLEVHSFNLPGRPGIESTSA----TRVTVMLLNLSCNLLALGTEGGGVHFLELPTLTLLN-KSLFQDEIMQSVPEEYKCGKSLGPVESLQEHPKDSDKILIGYSRGLVVLWDLSSRHVDNLFLGKQQ-----------------LESLVWER--SGNSFVSSHSDGGYMVWAVSSSNPCTHDPVSSTIPYGPFPCKAVNKILWRTTESGAPLVLFSGGMPRASYGDRHCLTILQDS-SHVTLDFTSRVIDFFTIHCTDTEKDFDEPSALVVLLEEELVVIDLQMPGWPTVPAPYLAPLHSSAITCSCHISNVPPKLWERVISAGQQQCP--LQNYENWPICGG---KNLAP-----DPKQKELLLTGHEDGTVRFWDASGVSLKPLYKLSTASIFQTDCEH-----NDSLTQAGEEEWPPFRKVGCFDPYSDDPRLGIQKISLCKYSGKLVVAGTAGQVIVMVLGD---EKSDHMIDVATVDLLQDREGFTWKGHDRLPPKSGSVV------FAPGFQPVVLVQCLPPAAVTAVTLHAEWNLIAFGTSHGFGLFDYHRRSPVLARCTLHPNDSLAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRVVVNSPTSKVQEANAHLAD----HDAEVTPVQRRIEPRSADDSLSGVVRCLCFADTFLRDGTHHGPTMWAGTNSGSVYAYALDVPSQ----EKFSEQS----------VEALLGKEIQLMHRAPVVSIAVLDGRGNPLPEPYEVSRDLAKAPDMQGSHSVLIASEEQFKVFMLPKVSAKTKFKLTAHEGCRVRKVALANFTSVSSED-------------------------------------YSENALVCLTNMGDIHMFSVPALRPQVRYDCVRKEDISGIASCVFTKTGQGFYLISPSEYERFSLSARVITEPLCGVDVERPHDVSAH----SSSSTTLPPQANGTHKSQAESKSAET---------EDLLEEMRSVLSSPILDSPNSSADITLDTTGDLTVEDVKDFLMTVDEAENNFRNITEEDGRSAGILIN---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TJ91-1", "uniprot_id": "L2GL2_MOUSE", "id": "Q3TJ91-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "-----------MRRFLR-TGHDP----------------------------------ARERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENN------AVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSAT-----QVTEILPHSSGELLYLGTESGNVFVVQLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQ-----------------LENASWQR--DGCLIVTCHSDGSHCQWPVSSDTQ-NPEPLRSSIPYGPFPCKAITKIFWLTTRQGLPFTIFQGGMPRASYGDRHCISVVHNG-QQTAFDFTSRVIDFTVLSEADPAAAFDDPYALVVLAEEELVVIDLQTPGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNS--HFSTMEWPIDGG---TSLAP-----PPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDP-----SENLIAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELND---EAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVC------FEAGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSHKRRPGGPTGEAQAQAVNIKAERTGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRHCPSLWAGTNGGTVYAFSLRVPPA----ERRTDEP----------VRAEQAKEIQLMHRAPVVGILVLDGHNVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCRAED-------------------------------------YGEHHLAVLTNLGDIQVVSMPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSTKAKKHNRPS--NGNGTGLKMTSSGHVRNSKSQSDGDEK--------------KPGPVMEHALLNDAW-VLKEIQSTLEGDRRSY-GNWHPHRVAVGCRLSNGEAE-------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F3E6-1", "uniprot_id": "F7F3E6_RAT", "id": "F7F3E6-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "-----------MRRFLR-TGHDP----------------------------------ARERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENN------AVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSAT-----QITEILPHSSGELLYLGTESGSVFVVRLPGFCALHDRTISSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLRASRVLSHFLSHQQ-----------------LENVSWQR--DGCLIVTCHSDGSHCQWSVPSDTQ-SPEPLRSSVPYGPFPCKAITKIFWLTTRQGLPFTIFQGGMPRASYGDRHCISVVHNG-QQTAFDFTSRVIDFTVLMEADPVAAFDDPYALVVLAEEELVVIDLQTPGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNS--HFSTMEWPIDGG---TSLAP-----PPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDL-----SENLSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELND---EAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVR------FEAGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRASSHKRRPGGPTGEAQAQAVNTKAERTGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRHCPSLWAGTNGGTVYAFSLRVPPA----ERRADEP----------VRAEQAKEIQLMHRAPVVGILVLDGHNVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCRAED-------------------------------------YGEHHLAVLTNLGDIQVVSVPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAKARNHNRPS--NGNSTGPKRTS-GQVRNSRSQSDGAET--------------KPGPVMEHALLSDASGVLKEVQSTLEGDQGSC-GNWRSHRVAVGCRLSNGEAE-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1M3-1", "uniprot_id": "L2GL2_HUMAN", "id": "Q6P1M3-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "-----------MRRFLR-PGHDP----------------------------------VRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENN------AVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSAT-----QITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQ-----------------LENIWWQR--DGRLLVSCHSDGSYCQWPVSSEAQ-QPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHDG-QQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNA--HFSTMEWPIDGG---TSLTP-----APPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDP-----NENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELND---EAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVR------FEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSA--KAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPA----ERRMDEP----------VRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRAED-------------------------------------YGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNH-RP----GNGAGPKKAP-SRARNSGTQSDGEEK--------------QPGLVMERALLSDER-VLKEIQSTLEGDRGS--GNWRSHRAAVGCSLSNGGAE-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZE3-1", "uniprot_id": "L2GL2_DANRE", "id": "Q7SZE3-1", "name": "LLGL scribble cell polarity complex component 2", "aln": "-----------MKRFRR-HGHES----------------------------------QRDKHKQDLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENA------AVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFTLSGPPGAIPSVT-----RVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENNISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQ-----------------LESVWWME--DGESILSSHSDGSYCQWTVTGEDP-QTEPEKQETPYGAFPCKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSK-THEALDFTSRIIDFFVIREGE--NHKGEPSALVVLVEEELVVVDLQTEGWPVIQTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAHQNT--HYSRKPWPINGG---KNLAP-----DPPQRDLLLTGHEDGTVRFWDASGVCLYPMYKLSTAGVFHTDADP-----NDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSGYLTVAGTAGQILVLELND---EAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVL------FPPGFQPFALVQCQPPAVVTAIALHSEWKLVGFGTSHGFGLYDYNQRNNIMVKCTLNPSDQMAMEGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNN---AAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTPSLWAGTNGGAVFAYVLRVPPQ----ERRAEDP----------VTAHAAKEIQLMHRAPVVGLVVLDGKGAPLPEPLEVAHDLARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGS-RTDE-------------------------------------QLESCLVVLTNQGELHVISLPSIKMLVHYPCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTRWVVQPHCLVEPPLQMRSKSPS--SPVHRDLPDGVPTEHRNFKGDSEGYEN--------------SARQVMEHALLNDES-VLQEIQKSLEGDQTTFLENNLKTKPKAGNVLSNGD---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08111-1", "uniprot_id": "L2GL_DROME", "id": "P08111-1", "name": "Lethal(2) giant larvae protein", "aln": "-----------MLKFIRGKGQQPSA--------------------------------DRHRLQKDLFAYRKTAQHGFPHKPSALAYDPVLKLMAIGTQTGALKVFGQPGVELYGQHTLLNNSASELNVQLLEWVYGTGRILSLTAANQLILWEPVG----ATLLPIKTLPFDGKLK-----------KVSSLCCSLSKDLLWIGTEGGNIYQLDLHTF-TIKEPVIYHDVVLEQVPPAYKLNP--GAIESIRQLPNSPSKLLVAYNRGLCVLWDFESASVQRAYIAPGH-----------------GQSVGLTVNFEGSEFTWYHADGSYATWSIDNPEP---PSNVNYVPYGPDPCKSINRLYKGKRRSND-VIVFSGGMPRSAYGDHNCVSVHASDGHKVCLDFTSKVIDFFVTFENN----RDVAEVLVVLLEEELCAYDLTDPNICAIKAPYLHSVHASAVTCNYLASEVVQSVYESILRAGDEQDID--YSNISWPITGGTLPDNLEESVEEDATKLYEILLTGHEDGSVKFWDCTGVLLKPIYNFKTSSIFGSESDFRDDAAADMSAEQVDEGEPPFRKSGLFDPYSDDPRLAVKKIAFCPKTGQLIVGGTAGQIVIADFID---LPEKVSLKYISMNLVSDRDGFVWKGHDQLNVRSNLLDGEAIPTTERGVNISGVLQVLPPASITCMALEASWGLVSGGTAHGLVLFDFKNFVPVFHRCTLNPNDLTGAGEQLSRRKSFKKSLRESFRKLRKGRSTRTNQSNQVP------------------TTLEARPVERQIEARCADDGLGSMVRCLLFAKTYVTNVNITSPTLWSATNASTVSVFLLHLPPAQTAATAVPSASGNAPPHMPRRISAQLAKEIQLKHRAPVVGISIFDQAGSPVDQ-------LNAGENGSPPHRVLIASEEQFKVFSLPQLKPINKYKLTANEGARIRRIHFGSFSCRISPETLQSMHGCSPTKSTRSHGDGEADPNISGSLAVSRGDVYNETALICLTNMGDIMVLSVPELKRQLNAAAVRREDINGVSSLCFTNSGEALYMMSSSELQRIALATSRVVQPTGVVPVEPLENEESVLEENDAENNKETYACDEVVNTYEIKNPSGISICTRPAEENVGRNSVQQVNGVNISNSPNQANETISSSIGDITVDSVRDHLNMTTTTLCSINTEETIGRLSVLSTQTNKASTTVNMSEIPNINISNLEDLESKRNTTETSTSSVVIKSIITNISHEKTNGDNKIGTPKTAPEESQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38163-1", "uniprot_id": "SRO77_YEAST", "id": "P38163-1", "name": "Exocytosis protein SRO77", "aln": "MFKKSRHLKNVSNAIKSARVHD-----------------------------------VSNGINSKFFDTKKICTYGINGRITVTTFDYTQSLLAVATTAGEIHVYGQKQIEVVFTLKNRP------QIKHMRFIKG-IYLIAVDEKSNIIVLSVHSKQILTTVFCPN--------------------SITCIETDPSLDWMLIGLESGSILIYDVDRN------QMSKLKIENFQKSVFLPKERLSPVISIQWNPRDIGTILISYEH-ITVIYSFIDYKVKQHFFYQLEPYAPGGDLSTNIEKKRTPKVIQSLYHPNSLHILTVHEDNSLVFWDVNSGKLIHARSIFETHVNFPNPALKDCSFTETPAIFKVSWLCQRNPEYTSLLIATKATENPCLPQEITMIDLGGTPMYSVTSFDAMSKYYAKPVQQKLFSLIGKAPLINFLP---LPKASPYFGGCHDTNLILLLLEDGELETLIYPAGSFSSKASIFPRSLAWVRPTVTT----CIAQS----VQKNLWLGMMTIAQS-ESFLKGGIPATRNIRRHETRSALLTGHSNGSVRIWDASHSEVTDN--AVFEVNTAKVLNRATNLAIKNISFASETLELAVSSEVGDVILFKFETNKFYG--QLPKSDALQLKFSRFSLDDSKTILVDVSDRGPTN-----VKQGFIPSTVIHAK--KGAVSAIMNSNIGFVAVGFIEGTLIILDRRGPAIIFNENIRVISKAGSSYVSTVHFCVMEYGDDGFSSILMLCGTDIGELMTFK-----------------ILPATNGRFEVKFTDATKTNNQGKILGINSFAKDTGYSCSATISKMQGLSKGIAIPGFVTISGANDIRLVSPGKSK-----------DTHALFKYPIATSG-LSFIPIIDGKGERKLSTIMIVLLINGDIKVLTVPELKEVKNLRCPVPLSAQYVENSSILENGDIVIRTGKFQASLISVLNESATG-------------------------------------TNHTADISQHTPIDTLYNPDLKIGYRPQVNSLQWARGTIYCTPYQLDELLGGIERPESK---YEESAIARGCISSSSSNAARKLPPG--TEDHRYARPVRSSGRSNGYGVLKSVSR-----------AIETRLDTVETTINDYATTMGQTMNDAMEETGRDMMKSAVGF---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12038-1", "uniprot_id": "SRO7_YEAST", "id": "Q12038-1", "name": "Exocytosis protein SRO7", "aln": "MFG-SKRLKNVKEAFKSLKGQNSETPIENSKASFKSKNSKTSTISKDAKSSSSLKIPISSNNKNKIFSLAETNKYGMSSKPIAAAFDFTQNLLAIATVTGEVHIYGQQQVEVVIKLEDRS------AIKEMRFVKG-IYLVVINAKDTVYVLSLYSQKVLTTVFVPG--------------------KITSIDTDASLDWMLIGLQNGSMIVYDIDRD------QLSSFKLDNLQKSSFFPAARLSPIVSIQWNPRDIGTVLISYEY-VTLTYSLVENEIKQSFIYELPPFAPGGDFSEKTNEKRTPKVIQSLYHPNSLHIITIHEDNSLVFWDANSGHMIMARTVFETEINVPQPDYIRDSSTNAAKISKVYWMCENNPEYTSLLISHKSISR-GDNQSLTMIDLGYTPRYSITSYEGMKNYYANPKQMKIFPLPTNVPIVNILP---IPRQSPYFAGCHNPGLILLILGNGEIETMLYPSGIFTDKASLFPQNLSWLRPLATT----SMAAS----VPNKLWLGALSAAQNKDYLLKGGVRTKRQKLPAEYGTAFITGHSNGSVRIYDASHGDIQDN--ASFEVNLSRTLNKAKELAVDKISFAAETLELAVSIETGDVVLFKYEVNQFYSVENRPESGDLEMNFRRFSLNNTNGVLVDVRDRAPTG-----VRQGFMPSTAVHAN--KGKTSAINNSNIGFVGIAYAAGSLMLIDRRGPAIIYMENIREISGAQSACVTCIEFVIMEYGDDGYSSILMVCGTDMGEVITYK-----------------ILPASGGKFDVQLMDITNVTSKGPIHKIDAFSKETKSSCLATIPKMQNLSKGLCIPGIVLITGFDDIRLITLGKSK-----------STHKGFKYPLAATG-LSYISTVEKNNDRKNLTVIITLEINGHLRVFTIPDFKEQMSEHIPFPIAAKYITESSVLRNGDIAIRVSEFQASLFSTVKEQDT-----------------------------------------LAPVS-----DTLYINGIRIPYRPQVNSLQWARGTVYCTPAQLNELLGGVNRPASK---YKESIIAEGSFSERSSDDNNANHP-----EHQYTKPTRK-GRNSSYGVLRNVSR-----------AVETRWDAVEDRFNDYATAMGETMNEAVEQTGKDVMKGALGF---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .:: : :*: : . :. ::*:.* :* ::::* :*. : :. : . :: : . : : : :: : . : :* :.. : : : : . : ::: . :*:.*. : : :. :: : . . * *.. * . . * . : :. :*: . . : :: **: * . : .: . * : : :. : . . : : . : . : . . .*.:.:: :. : : *. .*:::: . :: : . . : *. :: .. .:. ::. . * : .. :: .:. . . : :.: : : . .: :: . . *:. . ..: ::. : . : : : . : : .: . : . . : . .: . .. * .. . : :: . :: . : * . .: : :. . : :.. . . . . .: . ", "identical_positions": 26, "similar_positions": 221, "identity": "2.04%" }, { "cls_id": "homologset.agr.FB:FBgn0002174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K5E4-1", "uniprot_id": "A0A0G2K5E4_RAT", "id": "A0A0G2K5E4-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAARCSPRWFRVAVGTPRLPAAAGRGVQQPQGGVVAASLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLTGTKSFPFVCTASFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGASS--SGQGY------WRGGP---SVDPEELFRKIFG--EFSSSPFGDFQN----VFDQPQEYIMELTFNQAAKG-VNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCSGSGMETINTGPFVMRSTCRRCGGRGSIITNP--CVVCRGAGQAK-QKKRVTVPVPAGVEDGQTVRMP-------------------VGKREIFVTFRVQKSPVFRRD-GADIHSDLFISIAQAILGGTAKAQGLY-ETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVP--KRLSSRQQNLILSYAEDETDVEGTVNGVTHTSTG------GRTMDSSTGSKDRR---EAGE-------------------DNE--------------------GFLSKLKKIFTS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M87-1", "uniprot_id": "DNJA3_MOUSE", "id": "Q99M87-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAAWCSPRWLRVAVGTPRLPAAAGRGVQQPQGGVVATSLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLTGTKSFPFVCTTSFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGTSS--SGQGY------WRGGP---SVDPEELFRKIFG--EFSSSPFGDFQN----VFDQPQEYIMELTFNQAAKG-VNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIITNP--CVVCRGAGQAK-QKKRVTIPVPAGVEDGQTVRMP-------------------VGKREIFVTFRVQKSPVFRRD-GADIHSDLFISIAQAILGGTAKAQGLY-ETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVP--KRLSSRQQNLILSYAEDETDVEGTVNGVTHTSTG------GRTMDSSAGSKDRR---EAGE-------------------DNE--------------------GFLSKLKKIFTS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EY1-1", "uniprot_id": "DNJA3_HUMAN", "id": "Q96EY1-1", "name": "DnaJ homolog subfamily A member 3, mitochondrial", "aln": "MAARCSTRWLLVVVGTPRLPAISGRGARPPREGVVGAWLSRKLSVPAFASSLTSCGPRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS---------AGFDPGASG--SQHSY------WKGGP---TVDPEELFRKIFG--EFSSSSFGDFQT----VFDQPQEYFMELTFNQAAKG-VNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISP--CVVCRGAGQAK-QKKRVMIPVPAGVEDGQTVRMP-------------------VGKREIFITFRVQKSPVFRRD-GADIHSDLFISIAQALLGGTARAQGLY-ETINVTIPPGTQTDQKIRMGGKGIPRINSYGYGDHYIHIKIRVP--KRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSG------GSTMDSSAGSKARR---EAGE-------------------DEE--------------------GFLSKLKKMFTS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27237-1", "uniprot_id": "DJTID_DROME", "id": "Q27237-1", "name": "DnaJ homolog l(2)tid, mitochondrial", "aln": "MMISCKK--LFVFR---QLPAVR-----------------RCLAAAAFST------PRATSYRILSSAGSGSTRADAPQVRRLHTTRDLLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREYDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQS---WQFRS---SIDPEELFRKIFGEGNFRTNSFDDFADSK-FGFGQAQEMVMDLTFAQAARG-VNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCNGTGFETVSTGPFVMRSTCRYCQGTRQHIKYP--CSECEGKGRTV-QRRKVTVPVPAGIENGQTVRMQ-------------------VGSKELFVTFRVERSDYFRRE-GADVHTDAAISLAQAVLGGTVRVQGVY-EDQWINVEPGTSSHHKIMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEEDTPGQIHGIANRKDGSKQATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEKSEGKDQWTDNEKTKAKEGGGSGSGQGDGGGGGFISKIKSMFN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35191-1", "uniprot_id": "MDJ1_YEAST", "id": "P35191-1", "name": "DnaJ homolog 1, mitochondrial", "aln": "--MAFQQGVLSRCSGVFRHHVGHSR------------------------------HINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKE-PDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQGSYPDIAVEADLKDSVKLSRGDILVRIRVDKDPNFSIKNKYDIWYDKEIPITTAALGGTVTIPTVEGQKIRIKVAPGTQYNQVISIPNMGVPKTSTIR-GDMKVQYKIVVK--KPQSLAEKCLWEALADVTNDDMAKKTMQPGTAAG------TAINEEILKKQKQEEEKHAKK-------------------DDD--------------------NTLKRLENFITNTFRKIKGDKKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : : .* * **: :.*. :******:******** **: *.* .** :: :***:**** **::** :* .* * .. . . . . :: *:** ** :. . .:. * . .::* :*. * * :. .. :* * * *. :*.*: * * *:* . * * * *** * * * *.* * : : : : :* *:::*:.**: :. :::: :**::. * . *: * *.:: * ****. : : :.: .* . .: * : . *: : .: ** :: ** * * . * : *: * . . * : : * . *:: . :.:::.::. ", "identical_positions": 102, "similar_positions": 122, "identity": "17.23%" }, { "cls_id": "homologset.agr.FB:FBgn0002183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4J0-1", "uniprot_id": "D4A4J0_RAT", "id": "D4A4J0-1", "name": "FACT complex subunit", "aln": "-MAVTLDKDAYYRRVKRLYSNWRK----GEDEYASIDAIVVSVG-VDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWS----DCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYP--------------PIIQSGGNYNLKFSVVSDKNHMH-FGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLK-ELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQY-KLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLV--DEDGPATVLTSVKKKVKNVGIFLKNEDDEEEEEEK-----DEAEDLLGRGSRA-ALLTERTR-------NEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPH-IREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTS--VRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLG--------KHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEE--QSRSMSRKR-KASVHSSGRGS-----NRGSRHSSAPP-------KKKRK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920B9-1", "uniprot_id": "SP16H_MOUSE", "id": "Q920B9-1", "name": "FACT complex subunit SPT16", "aln": "-MAVTLDKDAYYRRVKRLYSNWRK----GEDEYASIDAIVVSVG-VDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIDAIKESKSGKKIGVFSKDKFPGEFMKSWS----DCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYP--------------PIIQSGGNYNLKFSVVSDKNHMH-FGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLK-ELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQY-KLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLV--DEDGPATILTSVKKKVKNVGIFLKNEDDEEEEEEK-----DEAEDLLGRGSRA-ALLTERTR-------NEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPH-IREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTS--VRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAVMFGKKRHTDVQFYTEVGEITTDLG--------KHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEE--QSRSMSRKR-KASVHSSGRGS-----NRGSRHSSAPP-------KKKRK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5B9-1", "uniprot_id": "SP16H_HUMAN", "id": "Q9Y5B9-1", "name": "FACT complex subunit SPT16", "aln": "-MAVTLDKDAYYRRVKRLYSNWRK----GEDEYANVDAIVVSVG-VDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWN----DCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYP--------------PIIQSGGNYNLKFSVVSDKNHMH-FGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLK-ELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQY-KLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLV--DEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEK-----DEAEDLLGRGSRA-ALLTERTR-------NEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPH-IREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTS--VRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLG--------KHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEE--QSRSMSRKR-KASVHSSGRGS-----NRGSRHSSAPP-------KKKRK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRG6-1", "uniprot_id": "SPT16_DROME", "id": "Q8IRG6-1", "name": "FACT complex subunit spt16", "aln": "MSSFVLDKEAFVRRVKRLYTEWRAPSIGHDDALRNLDCIMSIVG-VEEDVMYSKSMALQLWLLGYELTDTISVFCSDAVYFLTSKKKIEFLKQTQNIT----EEGFPEINLLVRDRTDKDQGNFEKLIKALQNSKKGKRLGVFAKDAYPGEFSEAWK----KSLTASKFEHVDISTIIAYLMCPKDESEINNIRKASLVSMDIFNKYLKDEIMDIIDSDRKVKHNKLSDGCEAAIGEKKYTSGLDPRLLDMAYP--------------PIIQSGGAYSLKFSAVADKNPLH-FGVIVCSLGARYKSYCSNISRTFLVNPTEAMQENYTFLVSVQEEILK-LLVPGTKLCDVYEKTLDFVKKEKPSMVDNLPKSFGFAMGLEFRENSIVIGPKCQA-LLKKNMVFNLHVGISNLTNPEATDKEGKNYALFIGDTVLV--GEQSPASVMTPSKKKIKNVGIFIKDDSDEEDVDDKKTAKEDQGTEILGRSKRN-AVLESKLR-------NEINTEEKRKEHQRELAQQLNERAKDRLARQGNSKEVEKVRKNTVSYKSISQMPREPE-VKELKLYVDKKYETVIMPVFGIQVPFHISTIKNISQSVEGEYTYLRINFFHPGATMGRNEGGLYPQPEATFVKEVTYRSSNVKEHGEVGAPSANLNNAFRLIKEVQKRFKTREAEEREKEDLVKQDTLILSQNKGNPKLKDLYIRPNIVTKRMTGSLEAHSNGFRYIS--VRGDKVDILYNNIKSAFFQPCDGEMIILLHFHLKYAIMFGKKKHVDVQFYTEVGEITTDLG--------KHQHMHDRDDLAAEQAERELRHKLKTAFKSFCEKVETMTKSVVEFDTPFRELGFPGAPFRSTVTLQPTSGSLVNLTEWPPFVITLDDVELVHFERVQFHLRNFDMIFVFKEYNKKVAMVNAIPMNMLDHVKEWLNSCDIRYSEGVQSLNWQKIMKTITDDPEGFFEQGGWTFLDPES-GSEGENETAESE-EDEAYNPTDAESDEES-DEDSEYSEASEDSEESDEDLGSDEESGKDWSDLEREAAEEDRNHDYAADDKPRNGKFDSKKHGKSSKHSPSKSSKDKYNSRDKHHSSSSSGNKSSSKDKDRKRSRDDSRDNGHKSKKSRH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32558-1", "uniprot_id": "SPT16_YEAST", "id": "P32558-1", "name": "FACT complex subunit SPT16", "aln": "MEELNIDFDVFKKRIELLYSKYNEFE-------GSPNSLLFVLGSSNAENPYQKTTILHNWLLSYEFPATLIALVPGKVIIITSSAKAKHLQKAIDLFKDPESKITLELWQRNNKEPELNKKLFDDVIALIN--SAGKTVGIPEKDSYQGKFMTEWNPVWEAAVKENEFNVIDISLGLSKVWEVKDVNEQAFLSVSS-KGSDKFMDLLSNEMVRAVDEELKITNAKLSDKIENKIDDVKFLKQLSPDLSALCPPNYKFNFDLLDWTYSPIIQSGKKFDLRVSARSTNDQLYGNGCILASCGIRYNNYCSNITRTFLIDPSEEMANNYDFLLTLQKEIVTNILKPGRTPKEVYESVIEYIEKTKPELVPNFTKNIGSLIGLEFRDSNFILNVKNDYRKIQRGDCFNISFGFNNLKDSQSAN----NYALQLADTVQIPLDETEPPRFLTNYTKAKSQISFYFNNEEEDNNKKKS-----SPATKVPSKPDRNSKILRTKLRGEARGGAEDAQKEQIRKENQKKLHEKLEKNGLLRFSAADANGPDSEPRQYFKKYESYVRDSQLPTNIRDLRIHVDWKSQTIILPIYGRPVPFHINSYKNGSKNEEGEYTYLRLNFNSPGSSGG------ISKKVEELPYEESADNQFVRSITLRSKDGDRMSETFKQIADLKKEATKREQERKALADVVQQDKLIENKTGRTKRLDQIFVRPNPDTKRVPSTVFIHENGIRFQSPLRTDSRIDILFSNIKNLIFQSCKGELIVVIHIHLKNPILMGKKKIQDVQFYREASDMSVDETGGGRRGQSRFRRYGDEDELEQEQEERRKRAALDKEFKYFADAIAEASNGLLTVENTFRDLGFQGVPNRSAVFCMPTTDCLVQLIEPPFLVINLEEVEICILERVQFGLKNFDMVFVYKDFNKPVTHINTVPIESLDFLKQWLTDMDIPYTVSTINLNWATIMKSLQDDPYQFFLDGGWNFLATGS-DDEASDESEEEVSEYEASEDDVSDESAFSEDEEGSEVDDDISGDESEDYTGDESEEGEDWDELEKKAARADRGANFRD------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* :.: :*:: **:::. . :.:: :* : : * *: *: **:.**:. *: .: . : :::*. * :.*:: : : : ... : :: *:.:* :: . ** :*: ** : *:* *. .:. . *: :*** :: *: .* : :: : * . :.:.:: :* : *: : **:: * * : *: .* :. * ****** :.*:.*. : :: :: * * .: * *::.****: **::::*:: : :** **: :*:*::. * * . :**: .:: ::* **.:: ::.*.:* :*:***:..:::. * : :::. *.: .*:.:*.: :. . .*** :.*** : .* *. .:* .* .::.::::::.:::: ... . . .: .: .* :* : * :: *: *: :*::* :*::.. *:: . .: *: .*:. .: * ::::::::* * :*:*:*::* .**** : ** * . **:*****:** **:: * .: : * : . :: . .:.::*: * :::*. ..** *.: .:*:**.*: . . . :*.::::*** **: .:: * **:*: * ..::***:.*** :**.*.**:*:::*:*** .:::***: ***** *..:::.* :.:: *.*:* ** **. * *.. ** * : : :: : .: .**:*** *.* **: **:..**: * * :*:.*::**: :***** *:****::*:*::.* *: :*::*: ** :*:**.. *: *: .. .*** .***:: *** ** :***.** . . ..:..: *. * *: : : . . *.: . . ..: *.: *.:.*.*:**.:**.:* . ** : ", "identical_positions": 264, "similar_positions": 399, "identity": "23.3%" }, { "cls_id": "homologset.agr.FB:FBgn0002283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KNV8-1", "uniprot_id": "PCGF3_HUMAN", "id": "Q3KNV8-1", "name": "Polycomb group RING finger protein 3", "aln": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLN--LSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTQ0-1", "uniprot_id": "PCGF3_MOUSE", "id": "Q8BTQ0-1", "name": "Polycomb group RING finger protein 3", "aln": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGEACSAKQHLD-PRNGETKADDNSNKETAEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLN--LSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EV63-1", "uniprot_id": "F7EV63_RAT", "id": "F7EV63-1", "name": "Polycomb group RING finger protein 3", "aln": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEGELMLFS-SSSELGF---GSWTQTLSSQHPYFP---HAIVLDSPLDAQKKVRHTQKHGHSLLRRKSQIFICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLN--LSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VV77-1", "uniprot_id": "Q9VV77_DROME", "id": "Q9VV77-1", "name": "Polycomb group RING finger protein 3", "aln": "-MERRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQYISFDRTMQDIVYKLVPKLQEDESRRERDFYKSRNMPCPKDITQNHE-------------------DDNEKVMDAHAES-DFHRLDEQVNVCLECISNNFKNLQRRFIRCSSQATITHLKKLVAKKILNGIEKYREIDILCNEELLGKDHTLKFVYVTRWRFRDPPLRLQFRPRVEL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::** **.****::*.**:**************:*****:***::***** :**********..************* *** * . .: . . . :: . . .. . * ..*: :**** *.:::.*:*::****:***: ****::***: :..:.*:*******:********** ******:..** *::**:::* ", "identical_positions": 119, "similar_positions": 60, "identity": "48.77%" }, { "cls_id": "homologset.agr.FB:FBgn0002284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18421-1", "uniprot_id": "PSB1_RAT", "id": "P18421-1", "name": "Proteasome subunit beta type-1", "aln": "MLS-TAAYRDPDRELVMGPQGSAGPVQMRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN-KAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNM---QNVEHVP-----LTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVPLRKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09061-1", "uniprot_id": "PSB1_MOUSE", "id": "O09061-1", "name": "Proteasome subunit beta type-1", "aln": "MLS-TAAYRDVERELGMGPHGSAGPVQLRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN-KAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNM---QNVEHVP-----LTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVPLRKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20618-1", "uniprot_id": "PSB1_HUMAN", "id": "P20618-1", "name": "Proteasome subunit beta type-1", "aln": "MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN-KAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNM---QNVEHVP-----LSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRF3-1", "uniprot_id": "PSB1_DANRE", "id": "Q6DRF3-1", "name": "Proteasome subunit beta type-1", "aln": "MIS-AQAYGENGK---MKEYHYTGPVEHKFSPYAFNGGTVLAVAGEDFAIVASDTRLSEGYSIHSRDSPKCYKLTDTTVLGCSGFHGDCLTLTKIIEARLKMYKHSNN-KSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVGSYQRDTYKAGGSASAMLQPLLDNQIGFKNM---ENVEHVP-----LTQEKAVQLVKDVFISAAERDVYTGDALKVCIVSKEGIKEEIVPLRKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40304-1", "uniprot_id": "PSB1_DROME", "id": "P40304-1", "name": "Proteasome subunit beta type-1", "aln": "-MS-RLGFEQ------FPDYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKVRMQSYEHTHL-RTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNL-EDADKIK-----LTKERAVSVASDTFISAAERDIYTGDSVLINIITKDGIEVRTLTLRQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23724-1", "uniprot_id": "PSB6_YEAST", "id": "P23724-1", "name": "Proteasome subunit beta type-6", "aln": "MATIASEYSS---------EASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *.** ***:::.:**:**:::*.*** .:.*::* ..* :. *:.. * .* :*. :: :: *.. : : :: : * :. :*.:******* .*: *:*::*:*.***:**:* :: :***:*.::: *.****:..** :: *: :..: :. * * **:**.: .**.: : *::*:*:. . *::*", "identical_positions": 67, "similar_positions": 90, "identity": "26.8%" }, { "cls_id": "homologset.agr.FB:FBgn0002354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSY5-1", "uniprot_id": "A0A8I5ZSY5_RAT", "id": "A0A8I5ZSY5-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAASSEPHEPE----KKPVKLLGILDIENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGYWFHCRYNFAKQRIQERIAREGIKDQ---------------HFIR-KHP-PQS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7J4-1", "uniprot_id": "COX20_MOUSE", "id": "Q9D7J4-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAAAPEPHETE----KKPFKLLGILDVENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGCWFHCRYNFAKQRIQERIAREGIKNK---------------ILYESTHLDPERKMKTNNSS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RI15-1", "uniprot_id": "COX20_HUMAN", "id": "Q5RI15-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAAPPEPGEPEE---RKSLKLLGFLDVENTPCARHSILYGSLGSVVAGFGHFLFTSRIRRSCDVGVGGFILVTLGCWFHCRYNYAKQRIQERIAREEIKKK---------------ILYEGTHLDPERKHNGSSSN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH88-1", "uniprot_id": "COX20_DANRE", "id": "Q6DH88-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MTE--EDGKTQ------GMKVLGILDIHNTPCAREAILHGAAGSVAAGLLHFLATSRVKRSFDVGVAGFMITTLGSWFYCRYNNAKLRFQQRIIQEGLKNK---------------VFYEGTDLDPTLKKTGDK----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG00-1", "uniprot_id": "Q9VG00_DROME", "id": "Q9VG00-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "-------------------------------------------------------MAEEPEEPAKS-------FVIFG-RDVAQIPCFRNSFLYGISGGIGIGLLTFLGTSRTHLSTHVGFGSFFCGTIAYWMTCRYQWSVRRFEQQQLREAMRRQ---------------ALYEGTQRERDLDLKSA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04935-1", "uniprot_id": "COX20_YEAST", "id": "Q04935-1", "name": "Cytochrome c oxidase assembly protein COX20, mitochondrial", "aln": "MRWWPWSNQTEDQKQQQQPQGKADGDRVLTNYSRGQKILLEDTPPKFADDLSNSQLAKKQERATLKEAWDSIRWSDFSLQKLTSIPCFRDAGMLGFSSMFLMGSIIFIYHKSPTKATNWAMSSLILGSIVGWEQCRLKRQKSFQIAQLAKETVAKKEKPMLHNVPHDPSLPGQWEAAKNEKQSQFEQSNQNLSQASSEKKWYKFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . :. .: . ** *.: : * . . * *: . : . ....:: :: * ** : : :* : : . . ", "identical_positions": 11, "similar_positions": 32, "identity": "5.37%" }, { "cls_id": "homologset.agr.FB:FBgn0002413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMK2-1", "uniprot_id": "KC1E_MOUSE", "id": "Q9JMK2-1", "name": "Casein kinase I isoform epsilon", "aln": "MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGS--------------------------------------------------ATRALPPGPPTG-----ATANRLRSAAEPVASTPASRIQQTGNTS------PRAISRADRERKVSMRLHRGAPANVSSS---DLTGRQEVSRLAASQTS-------VPFDHLGK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49674-1", "uniprot_id": "KC1E_HUMAN", "id": "P49674-1", "name": "Casein kinase I isoform epsilon", "aln": "MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGS--------------------------------------------------ATRALPPGPPTG-----ATANRLRSAAEPVASTPASRIQPAGNTS------PRAISRVDRERKVSMRLHRGAPANVSSS---DLTGRQEVSRIPASQTS-------VPFDHLGK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DC28-1", "uniprot_id": "KC1D_MOUSE", "id": "Q9DC28-1", "name": "Casein kinase I isoform delta", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR--DREERLRHSRNP--------------------------------------------------ATRGLPS----------TASGRLRGTQEVAPPTPLTPTSHTANTS------PRPVSGMERERKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQIP-------GRVASSGLQSVVHR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06486-1", "uniprot_id": "KC1D_RAT", "id": "Q06486-1", "name": "Casein kinase I isoform delta", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR--DREERLRHSRNP--------------------------------------------------ATRGLPS----------TASGRLRGTQEVAPPTPLTPTSHTANTS------PRPVSGMERERKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQIP-------GRVASSGLQSVVHR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48730-1", "uniprot_id": "KC1D_HUMAN", "id": "P48730-1", "name": "Casein kinase I isoform delta", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR--DREERLRHSRNP--------------------------------------------------ATRGLPS----------TASGRLRGTQEVAPPTPLTPTSHTANTS------PRPVSGMERERKVSMRLHRGAPVNISSS---DLTGRQDTSRMSTSQIP-------GRVASSGLQSVVHR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P3K7-1", "uniprot_id": "KC1DB_DANRE", "id": "Q6P3K7-1", "name": "Casein kinase I isoform delta-B", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGANRTAEEADRERR--ERDERMRHSRNP--------------------------------------------------AARGIP-----------AASGRPRPTQDGAPPTPLTPTSHTANTSS-----PRPVTGMERERKVSMRLHRGAPVNVSSS---DLTGRQDTSRMSTSQNS-------IPFDHHGK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2E3-1", "uniprot_id": "KC1DA_DANRE", "id": "Q7T2E3-1", "name": "Casein kinase I isoform delta-A", "aln": "MELRVGNRYRLGRKIGSGSFGDIYLGTDITTGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGGAR--EDPERDRR--DREERIRQGRIP--------------------------------------------------LPRVMLP----------TSSGRPRGTQEVAPAPPLTPDSHT---------------GMERERKVSMRLHRGAPVNVSSS---DLTGRQDCSRISTSQAH-------SRVP-SGLQSAVPR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76324-1", "uniprot_id": "DCO_DROME", "id": "O76324-1", "name": "Discs overgrown protein kinase", "aln": "MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAA--------------------------------------------------AAVAAAAAASSHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGG-----NGGGNGSQLIGGNGLNMDDSMAATNSSRPPYDTPERRPSIRMRQGGGGGGGGVGVGGMPSGGGGGGVGNAK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29295-1", "uniprot_id": "HRR25_YEAST", "id": "P29295-1", "name": "Casein kinase I homolog HRR25", "aln": "MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNANSNAASASNSTDNKSETFNKIKLLAMKKFPTHFHYYKNEDKHNPSPEEIKQQTILNNNAASSLPEELLNALDKGMENLRQQQPQQQVQSSQPQPQPQQLQQQPNGQRPNYYPEPLLQQQQRDSQEQQQQVPMATTRAT--QYPPQINSNNFNTNQASVP-----PQMRSNPQQPPQDKPAGQSIWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****.::*:************* *: : *********.::::****. **:.*: :.**:*** * * * **:**.**::***********:* *:**:***::** **:.**:***.:.*****:********:*::*. *::*****:**:** .: :********.*********:*********************:** *:********:.*:***:** ***:...: .**.* * ** *: :*:.::**::*** .* :**::* : : *::***.:*:: . : : : . . . . : . . . . : : . : .: . . ", "identical_positions": 182, "similar_positions": 102, "identity": "36.33%" }, { "cls_id": "homologset.agr.FB:FBgn0002431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62671-1", "uniprot_id": "UBR5_RAT", "id": "Q62671-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "----------MNKQAVKRLHMLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRICRIGFSVQPDRLELGKPDNNDGSKLNSSSGTGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSE------------------------LLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNPDKKNTPVQSPVSLGEDLQWWPDKD-GTKFTCIGALYSELVAVSSKGELYQWKWTESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLEN-NLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGVQSLN-VRGGRQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKSMEK-----------------------------ASKTIETKPESKQEPVKTEMGPPPSPAS-TCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------SSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSVAFLGQNERSVAIFT----AGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAIIIMAVEKQTLMQHILRCDYEACRQYLVNLEQAVVLEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNG-------PGNRAGSSSSRS----LRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPSMDPDGDIDFILAPAVGSLTTAATGGGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSAVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEVSGSEKEE--DVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRP-PRIRED--------------RNRKTASPD-DSDMPDHDLEPPRFAQLALERVLQDWNALRSMIMFGSQENKDPLSASSRIGHLLPEEQ-VYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGREEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGHHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTSQSATLNDKDDESLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSAGSGKCLVEVTMDRNCLEVLPTKMSYAANLK-------------------NVMNMQN----------RQKKAGEDQSMLAEEADSSK------------------------------------------PGPSAHDVAAQLKSSLLAEIG----------------------LTESEGPPLTSFRPQCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSL-EVDRDRDLLIQQTMRQLNNHFG--RRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNAN--KGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGN---PSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVEEAMELIVAHGRENGADSILDLGLLDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAVDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TP3-1", "uniprot_id": "UBR5_MOUSE", "id": "Q80TP3-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRICRIGFSVQPDRLELGKPDNNDGSKLNSSSGTGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSR------ERDSE------------------------LLRERESVLRLRERRWLDGASFDNERGSTSKEGESNPDKKNTPVQSPVSLGEDLQWWPDKD-GTKFTCIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLEN-NLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKSMEK-----------------------------ASKTLETKPESKQEPVKTEMGPPPSPAS-TCSDASSIASSASMPYKRRRSTPAPREEEKVNEEQWPLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------STNTTCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKTEILAVNVDSKGVHAVLKTGSWVRYCVFDLATGKAEQENNFPTSSVAFLGQDERSVAIFT----AGQESPIVLRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAIIIMAVEKQTLMQHILRCDYEACRQYLVNLEQAVVLEQNRQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNG-------PGNRAGSSNSRS----LRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPSMDPDGDIDFILAPAVGSLTTAATGSGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSAVLQPYLRELLSAKDARGMTPFMSAVSGRAYSAAITILETAQKIAKAEVSASEKEE--DVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRP-PRIRED--------------RNRKTASPE-DSDMPDHDLEPPRFAQLALERVLQDWNALRSMIMFGSQENKDPLSASSRIGHLLPEEQ-VYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQASSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGHHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNPQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSVMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRR-ATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTSQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSAGSGKCIVEVTMDRNCLEVLPTKMSYAANLK-------------------NVMNMQN----------RQKKEGEEQSLLAEEADSSK------------------------------------------PGPSAPDVAAQLKSSLLAEIG----------------------LTESEGPPLTSFRPQCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSL-EVDRDRDLLIQQTMRQLNNHFG--RRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNAN--KGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGN---PSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLLDSSEKVQ-ENRKRHGSSRSVVDMDLEDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95071-1", "uniprot_id": "UBR5_HUMAN", "id": "O95071-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSE------------------------LLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDLQWWPDKD-GTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLEN-SLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEK-----------------------------ASKTTEAKPESKQEPVKTEMGPPPSPAS-TCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------SSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERNVAIFT----AGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVVLEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNG-------PGNRAGSSSSRS----LRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEISSSEKEE--DVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRP-PRIRED--------------RNRKTASPE-DSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQ-VYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRR-ATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPTKMSYAANLK-------------------NVMNMQN----------RQKKEGEEQPVLPEETESSK------------------------------------------PGPSAHDLAAQLKSSLLAEIG----------------------LTESEGPPLTSFRPQCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSL-EVDRDRDLLIQQTMRQLNNHFG--RRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNAN--KGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGN---PSDDPEPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NV16-1", "uniprot_id": "A0A8M1NV16_DANRE", "id": "A0A8M1NV16-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNCNSHPHLIPLEQAKLKQCVVGPNHAGFLLEDGRICRISFAVQPDRLELGKPDGNDGSKLSSVSGAGRSSRPGRTSDPPWFLSGSDTLGRLAGNTLGTRWSSGVNGGGGGSSGRSSTAARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSE------------------------LLRERESVLRLRERRWLDGASFDAERGSTSREGEPSLDKKSVPLQSPVTLGEELQWWPDKDYVTKFVSIGALYSELVAVSTKGELYQWKWNEPEPYRNAQNPSIHHPRVPFLGLTNEKITHLSANSIRATVATENNKVATWVDETLSTVAAKLEHGAQTFPELQGERIVSLHCCALYTCAQLEN-SLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSIPNITVGTQVCLRNNPLYHAGAVAFSVNAGIPKVGVLLESVWNMNDSCRFQLRSPESLKNMEK-----------------------------NTKTQETKTESKPELVKTEMGPPPSPAS-TCSDTSSIASSASLPYKRRRSTPAPKEEEKVNEEQWPLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------SSSVSSQSAAPTDSDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKAEILAVNVDSKGVHAVLKTGSWVRYCVFDLATGKAEQENHFPTSNLAFLGQSERNVAIFT----AGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPIASLGMGVHSLANLPSNSTIKKKAAIIIMAVEKQTLMQHVLRCDYEACRQYLISLEQAMLLEQNPHALDTLLGHRCDGNRNVLHACVSVCFPVSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNS-------SGNRTGSSSSRG----LRLREMMRRSLRAAGLGRHESGPSSSDHQDPVSPPIAPPSWVPDPPPMDPDGDIDFILAPAVGSLTTASTGTSQGPSTSTIPGPSSEPSVVESKDRKANAHLILKLMCDSIVLRPHLRELLSAKDARGMTPFMLAVSGRAYPAAITVLEAAQKIAKGEPGLGEKEDTASVFMEMICPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKAARLDLLYRLLTTTNLVTTPNSRGEHILLFLVQTVARQSVEHCQYRP-PRIRED--------------RNRKAASAE-DSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIAHLLPEEQ-MYLNQQSGTIRLDCFTHCLIVKCAPDITFIDTLLGTLVKELQNKYTPGRREEAINVTRRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCRRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAVQGSEELFSVEPLPPRPSPDQSSSSSQSASSYIIRNPQPRRSSQSQTARGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDDQEEQGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDVDQETFLLDEPLERTTGSAHANSAAQAPRSMQWAVRTTPSQRSGGGAPSSSSAPAASSTGLIYIDPSNLRRSSAISTSAAAAAAALEASNSSSYLTSASSLARAYSIVIRQISDLMSLIPKYNHLVYSQYPAAVKLTYQDAVNLQNFVEDKLIPTWNWMVSIMDSTEAQLRYGSALSSAGDPGHPSHPLHASQHAGRRERMTAREEASLRTLEGRRRAATLLTARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNLQTTLDTTQIDRKRNRELLELGLDNEDSEHENDEDTNQSSTLQDKDEEPVPAETGQHHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSYMASKGLTDLTVDMNCLQILPTKMSYSANMK-------------------NVMSMES----------RQR-GGEEQPVAEQEMDVSK------------------------------------------PGPSPHDLAAQLKSSLLAEIG----------------------LTESDGPPLPTFIPHCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNLQSRDLAL-EVDRDREQLIQQTMRQLNAHFG--RRCTTTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNDKLPNLDCVQSVS--KGMQANLMQRLRNR---DRERER-----RSGGLRAASRRDRDRDSRRQLSIDTRPFRPASEGN---PSDEPEPLPAHRQALGERLYPRVHAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVEEAMELLITHGRENGADSILDLGLLDTPEKAQQENRKRHGSTRSVVDMELDDPDDGDDNAPLFYQPGKRGFYSPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLIRHSQTEEAEAVFAAMDLAFAIDLCKEEGAGQVELLSGGVNMPVTPLNVYEYVRRYAEHRMLVVAEQPLHAMRKGLLDVLPKNALEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51592-1", "uniprot_id": "HYD_DROME", "id": "P51592-1", "name": "E3 ubiquitin-protein ligase hyd", "aln": "MVSMQFVLQPLPGSDDQFIERIREVSDKVNRFGYGSHRIFEQLKIP-VKEVVIGPAHIGVLLEDGKAFRVSFSINSEKLDLTKSD----AKCSTSGGSGTASASKAPSS-------SRPMARSRARLLRATGRSNSTGQGSGS------------RSTGVIIGGSTS------SRPLVTVPATYVPEELISQAEVVLQGKSRNLIIRELQRTNLDVNLAVNNLLSRDDEEAEDTEEGADN-YVP-EDLISLLDNGFSGDNNSVIIDPSDGLFSEEIFSN-YSSIRNLLFDRIRSERSNANANAADSNQSTTRSTSSGTALTGNSGLSAQISVNADREAFSRWRDRQYYGPRRWISKDDYTWEKDADSKKKEPSPMLSPIWISEELQPWPEKS-SVRFKTIGALYSEFIALSESGDLYQWRWSDAEPYK-SETENVYHPKTVSLNIV-ERVELISANFIRCSVVTETNRVATWMDEQLGYIGAKLEHSCCAFNEFISDSITKIYVCSLYTVVKTESNNIYWWGVLPFDQRRFLWDKFRTKTKKPFKVVAT----DINVGAQVIMKKCPMYQSGSIGFTCSNGVPKVGQLLNSVWTFTDVCRMKIININTNSGVDKSQAAGNNLNAHGITPDKDLPKSTAMPSTGSSKNGQSFSNSKESTDRIDMPPPPSPASSTCSDTGSVTSHKRTKRATTKEDSNAPQEGRKDEELWEVKDVVFVEDKVG-PVGKVLKVDGDFVAVRFPAINAAAVAAAAAATSSTSNTASTSKEEGKEDDWQQCRLLRREDVQIFRTAMSTRGPDWLQKQPKKINVGGDAAGAQILTLAVDSRGIHVIKKVLGKIHYSLYNLYNCKQEQNCLFPTDCNSFIGSTPGNILMACNDDCSGNSSTIVLRDGNGALYPLAKDCLGSIKDPQWFDLPPVKSITMSTISLPAMLSGVNLKSKVCMTALLFDTQKLMPHILRCDVKNSFAALGRLER-----EDQADTALVVEERCDGARNIFHACVIMCAPSSNKDSPPDSPSGGVEKKSLVGLSVARSIPTVSTSAYVSSIAFGASASSSNENSSFATMSSSAAGSASSTSRDNRTNLRDMMNRLINSDQAEQSGSQPMATNNEDHAYIPWPAETPAASNLSASSSQNVSDSIEDDISKIIPSSS---QSSMLSNIKLGSP-TYTFDLAQRREHALTILQQMCVSPALRPYLCHMLSTKDAQGQTPFMLSVSCRAYEAGIILLNTILMLSEQDP---------QLKEAMIFPNGSPADQSPLHVICYNDTCSFTWTGADHINQNIFECKTCGLTGSLCCCTECARVCHKGHDCKLKRTAPTAYCDCWEKCKCKALIAGNLTKRFALLCKLVSCTDLVTKFNSKGESILLFLIQTVGRQIVEQRQYRFSVRVRNVSTAATGATGNNSVISNRKTSAAEIDNDMPDHDLEPPKFARKALERLLIDWNAVRSMIMSGAERGDVPNPAGSASENSNSEGFNMFIQTQHGSTLLDKFTHSLIVKCTSDH--LDTLLLTLVRELQNASVSNRSKEAEEVVRRFVRSVARVFVIFNLEKQPNPEKRKSHSSCNKYVQSCVKVFQTLHKISIEELCEVSEALIAPVRLGVVRPTAPFTMSSSNLD---NSDDLFSVDPLAP---SNVESPSEQ----ILVHDAGNDQSANFNIQQNYDVVAMETIRDASESEEVIN---REANSHNQDDELIENQRNEDGMQDDESDND-----FTFNDAETESDSDDNQSNQE---VQRSVQAGATVGSEN---DIGVLFLEDESGDSSAQEEDGSEDGESDDQSDEFNFNEQQLERRSTNSNAR-SDLAPQTMQWAIRSRDTARSSVRVPTG--------SNMVFIDPMALRRS-TVPASTTVTTPSIEP---HTMATTASNLARAFGITIRQISELISILS-YN--VLNDIETSLKIQNDEAIAVQAFVEKRLKATWDWMFTVMDGTEAQLKFGAYLTNYTDPNHPLHPLNLSAQASSSQTPAPATSSSVNGVN-------IMGS-----NSRRDFFTYCLSLMRSHTSEHRDALPVLDITALRHIAYVLDAFVYYMRNDSGFYDKQDTISGRINNLSPMTESYDTDD-ELANLEEFNADVQMSASSMPSGSQGT-RRHAFFARSESTLSLGCSAPEGFELPLDMAMPLADKPHLLQPNSKRQELFANLP--LLVTTNANNSGATNDGDGGSIFDYTPTRLGFSNSLKRNERVYETVPIDSSKTGDGNVTNKAEGSTDSNIYVQLKKKQGSDDFKSHKEADGNQSKYEKVVLMETDDSLPSTSKSTEALMATRPEVIIAPNKASVSPATAARSVIVLAGGSCLKTIDSDINNYSASNLSTAEQAKCDTQYQKSTSDHLLLFPARGSQFYQSNFSELPSWNFLLSRWKLTLDLFGRVFMDDVGMEHGSVLPELRGFPVKEMRFRRHMEKLRNGQQRDLVLCKLERNRESLIVQTFKELNTQFGNQSRRIQPPITFNRVKVTFKDEPGEGSGVARSFYTSIAEALLASAKIPNLESVQVGTNHSKYVVPFSSILRSRTVSGSSRDQSTLQRRGSNSKILWRSARER---KALNLDARPYTPPNSSDNATPESLNDHLSVHLQQIGERLYPKIHSINQTHAPKITGMLLEIPTPQLLSVISSDETLRQKVNEAIEIITFKQK--------------SETSAQSSQPK---KSPSVVVVDPVD----DDNEPLFYSPGKRGFYTPRQGFASFERINAFRNIGRLIGLCLLQNELLPLFLQRHVLKYILGRKIKFHDLAFFDPALYESFRQIIQNAQTKEGEETINRMELCFVIDLMKEEGCGNRELIPGGRDVAVTSSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDLRLLLNGVGDINVSTLISYTTFNDESSEGPDKLLKFKKWFWSIVEKMNIMERQDLVYFWTGSPALPASEEGFQPLPSVTIRPADDSHLPTANTCISRLYIPLYSSKSILRSKMLMAIKSKNFGFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :****:*:*::. .** : *: . :*: *:** * ..*****: *:.*:::.::*:* *.* :* .: .*:* :* . .*. * .:.* .. * : *. * *.** *.* ** * *:* .:**: :********:********.:*************************:.:* :: *.: *:* ***:**** .: . : ***** :*.:***:* *.*:*. :.*: *.* **: : :**:. * *:*:: . : : . * .:. . .*: *: **: :.*:** **:*. .:* *******::*:* .*:****:*.:.***: ::. .::**:. *.:. *:: :*** **.:*.**.*:****:** *. :.:**** . :: *: .: *..:: *:*** .: *. .:*****:**.**: : :* *:*.*** . .. : * ** ::: *:*::*::.*: . *:**** *::***.:.* **::: . :: ..::* :*. :: .:** . : :* ******* ****:.*::* :. . . :* : :** * :::****** . ********** :***:**. ::... :: : . .. *:***** :::*:.:*. :.: ** :*: ***: : ::**:: ***:*:*.: *. . ::*.:::* . * **: ***. :*:*. .: : :*:.*.*:******::**:****:*.*:**:*:****: *: *.. ** : :. .:*.*..: : .:.*.** *:**** : . * **: :: .: .**** **::**** :* * ***:: :. : *::::. . : *.:** . *. *** ... :**:.* . .**:**.* :.: : : . :::::* . * .. : ... . ... ::. : :..: .::: *.. *.* *. . ..: :*: :* **: :* * .*:*:* .:**:***:* **** :** *** *.* :*:: ::: : .: *: *.*: .*:***:*:* ***********:****:****:**** ***********************:**************:****: : *: ** :*:: *:*** **:** :****:***.** **: *** *:*: ***:::.: *.**********:**: ****:* ****::**** *::... * .*.* : .* :::: * *: ** ***.*****:.* :**** ***:**** ...* :** *. **:*********:.:* .. :*.:. : : .* :***:* ::****:*:*:**.***:*:.*******::*:.:* .*::****:**.* .: *.*.* ::::. : :: : :. : : : *. **:: * : *::::* *:: : :* :*:..::. : *******:.*:***: :*** :.**.*** .: .:* **:* ...:.:.*.* ..:*** .:* : :: *** : .::*. : **::****:*. *:. .*:. :.:::*** **** ::.:*::.::.::*. : *:**.****:.*.*****:*:.::. ** * .: :::*: ::*: :* :**.:* .**:**.::**.*****::*: *:. **.** ***: * ::. : :. .:*:. :: :: : .:* **:.*.*******..** *.*****: :*:*:***::*::*::: . : . * .. . : . *.:* * * :: . . :. .. . . * :.*.** **:* *** .*: **:** *:****:*******:::::**.. . * :: .. : . . :: **::.:: .:* ** . . :: *.:: :* : .: *..:. .: . .* * *. :* . * * .: * :. : * ::**.**:*:*:*******:*** * **:*.** ** *** :***.****** *.*** * :::*:*: ** **:::** :** * .*::.:**********************:**:*:*:. *:***:.:* . . . : . **.* . .*:: *... : * *:* : *.:*:**: *....: *.. : *..* * :******:::::: :.*.********:...*** :::*:::** :*:**:*:: : : : ..* .: * .: *** :: * *** ****.*******:** * : *:*.******::********* *: *:***:* :****:::**:*****.:***:**:* :*:.:.: .: *:*.*.:** **** *: **:..* ::.**. *::****:*:*:*:: *:.*.*::.*::****.*:: :*****:***:** *::**. ***:*:*****.*..:***:**:*******:*.: **********.**:**********:**:****.**.*************:******.**:.*:*:***:******", "identical_positions": 1112, "similar_positions": 941, "identity": "36.75%" }, { "cls_id": "homologset.agr.FB:FBgn0002466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSL7-1", "uniprot_id": "CTRO_RAT", "id": "E9PSL7-1", "name": "Citron rho-interacting kinase", "aln": "------------------MLKFKYGVRNPSEASAPEPIASRASRLNLFFQGKPPLMTQQQMSALSREGVLDALFVLLEECSQPALMK-IKHVSSFVRKYSDTIAELRELQPSVRDFEVRSLVGCGHFAEVQVVREKATGDVYAMKIMKKAALRAQEQVSFFEEERNILSQSTSPWIPQLQYAFQDKNNLYLVMEYQPGGDLLSLLNRYEDQLDENMIQFYLAELILAVHSVHQMGYVHRDIKPENILIDRTGHIKLVDFGSAAKMNSN-KVDAKLPIGTPDYMAPEVLTVMNEDRRGTYG------LDCDWWSVGVVAYEMLYGKTPFTEGTSARTFNNIMN------FQRFLKFPDDPKVSSELLDLIQSLLCVQKERLKFEGLCCHPFFARTDWNNIRNSPPPFVPTLKSDDDTSNFDE-------PEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSKALGYLGRSESVVSGLDSPAKISSMEKKLLIKSKELQDSQDKCHKMEQEMARLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDL-GKPEVGECSRLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLETMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES---QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLD----EASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKK---------------VPLQYNELKLALE----KEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKEASTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKVSSPGLQSKEPSSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSD-QVVLVGTEEGLYALNVLKNSLTHIPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDVSPNIFEAVKG----------CHLFAAGKIENSLCICAAMPSKVVILRYNDNLSKFCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLEEFLDKNDHSLAPAVFASSTNSFPVSIVQANSTGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSLGTPARAYLEIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEQHRVPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYRDREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49025-1", "uniprot_id": "CTRO_MOUSE", "id": "P49025-1", "name": "Citron Rho-interacting kinase", "aln": "------------------MLKFKYGVRNPPEASASEPIASRASRLNLFFQGKPPLMTQQQMSALSREGMLDALFALFEECSQPALMK-MKHVSSFVQKYSDTIAELRELQPSARDFEVRSLVGCGHFAEVQVVREKATGDVYAMKIMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNNLYLVMEYQPGGDFLSLLNRYEDQLDESMIQFYLAELILAVHSVHQMGYVHRDIKPENILIDRTGEIKLVDFGSAAKMNSN-KVDAKLPIGTPDYMAPEVLTVMNEDRRGTYG------LDCDWWSVGVVAYEMVYGKTPFTEGTSARTFNNIMN------FQRFLKFPDDPKVSSELLDLLQSLLCVQKERLKFEGLCCHPFFARTDWNNIRNSPPPFVPTLKSDDDTSNFDE-------PEKNSWVSSSVCQLSPSGFSGEELPFVGFSYSKALGYLGRSESVVSSLDSPAKVSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQ-GKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES---QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLD----EASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKK---------------VPLQYNELKLALE----KEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQSKEPGSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSD-QVVLVGTEEGLYALNVLKNSLTHIPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDVSPNIFEAVKG----------CHLFAAGKIENSLCICAAMPSKVVILRYNDNLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLDEFLDKNDHSLAPAVFASSSNSFPVSIVQANSAGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSLGSPARAYLEIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEQHRVPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYRDREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14578-1", "uniprot_id": "CTRO_HUMAN", "id": "O14578-1", "name": "Citron Rho-interacting kinase", "aln": "------------------MLKFKYGARNPLDAGAAEPIASRASRLNLFFQGKPPFMTQQQMSPLSREGILDALFVLFEECSQPALMK-IKHVSNFVRKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYG------LDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMN------FQRFLKFPDDPKVSSDFLDLIQSLLCGQKERLKFEGLCCHPFFSKIDWNNIRNSPPPFVPTLKSDDDTSNFDE-------PEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSKALGILGRSESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQ-GKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEE------------------------------------------LEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES---QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLD----EASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALE----KEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQTKEPSSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSD-QVVLVGTEEGLYALNVLKNSLTHVPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDISPNIFEAVKG----------CHLFGAGKIENGLCICAAMPSKVVILRYNENLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLEEFLDKNDHSLAPAVFAASSNSFPVSIVQVNSAGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSAGTPARAYLDIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEHHRGPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYR--EGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PI41-1", "uniprot_id": "M9PI41_DROME", "id": "M9PI41-1", "name": "non-specific serine/threonine protein kinase", "aln": "MPPKMEPISVRTARLNNLILGKGAGVCAKPAGSASGSGIPASTRRSIVPVSTT---SAAVAEAICREGLLDAFCLLYNECDKDTLKKRDRNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQVK----EERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHG-PFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYERIKNHPFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRHKTRREQGVAKKSLTTNMKSNDFSGKDLPFIGYS-------FVHMEKSAISATTDEKLQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDNKSQVVADAKMEIKKLQQIIKEKTMELTTCKTQIKTLQSSAKIDEEMWSKKEATITDLLRLNRQKYEEAKIASEQRYEKQLADK-------KQELASTLQKLDARELEFNAKFEECKHLSMKLQNYKDMLQQIKEQNLKSETNHEEQRRQMAELYEQKLTDLRKKVRDSQDTNRRMTMEIKEIRTELDESISSSKSTQEAKNATERNIEEILRRLNEEIASNN----------------------------------ELHAEKVKLETKLQLKENETQEVRAECHRLERELQLAECRCQLAESSLATQVSPYETAPGSLTELNAIEDQLRADLLAAKESENHQKGRADQLQTLVTKLEQMLERFNEQSLSPTKSHSSRKQEGETVGDMLERQNEKLEDKLAAVREQMIVERQAARTANLSLWKVEKQLEEALSEKKLLARRMELTEDRIKKVQNASDEAQRMLKTSQEETRQRESRIEELKQELAAAKRDVLKEHRQWEKAEQERMKCKSEIIEHLANVHRLEQQETELRQKLRQIQSRFDGVTLEQKNTIRELQEEREKSRKANDSCLVLQKELKQLTDNFQRLKYACSITDSQLTEVETMLKSEQERNKSQKSQLDTLHEKLRERNDQLTDLRKQLTTVESEKRLAEQRA----QVLASEIDELRLNLKEQQKKLVAQQDQLVEQTNALFATQERAELLDGQNANYEAQTADSNREMVSLKEENARILSELFHKKEEVGNLQAEIRGLESAQANLHAEIDSLQDTLAEKEQFYVQRDIKSNATLAQHKKLIDYLQLKVEDLSAKKKKTLADKLFGSSHTNKENVSPNDVESSILYRALKEELKREQKMNSLLKEQLAQLNGTATLRSPRKSAAVNGDSDAPKQRPVSIAALPRSPQKQQQPLKRTTSQVELKTTAEKPTKVT--IENQAHHRFELALQE-SKVDAVNCVVCEKAVVAGSPFWKCKECKDVTHRKCRSNVQSHCGS-----------------TKPTAPSADDLSSIQSVSSLTLDSVDVAGGTTSGGEYIGS-----LVYSSDGAEDQAR-----------------------------------------------------------------------------------------------------KEIEVNCAFEVAEQQILLLGCNTGLYAYHLDSQRLVHISGLESVSCMSICKRLAKAIMVGTVGEKLYQCDYRQLESRCQSSSSCHKPVLETSAIELPFANRTPSEKWKLVLISDEAENALDSVAIAATSTRIVILKYDLKLHMFKPVRALDTATPVTSIFFTRHSAIVSSDKFYEIDLDNYAAEEFVDLSDK-----SMESTAKCQPLTAVRIS----RQEYLLCFAEYGVFVDEFGCRSRPYDLNWVYAPTGFVYRDPFLFISHYQSVQIVRLHRSFSKEMAS-----------------------------------------GDNASENSESPELQR---------VYLPHYMSTLLANSGDVN-------------------LYAVAIDQRPCNGTQKIYHLDTMQAFKQKFNISMETLSSVATSVTLGSTVTGNSI----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *. ..*. . . ::* .:. ... : ..:.***:***: * :**.: :* * ::::.**.*: * * ::*: .. ** :::*:* *:*.:*::* *: *.*:**** :** .: :.: ***:*:* .* *: :*******:::******* ****:***:.*: :**.: :****** :*:*::* **************:** *.***.***.** :: : * : *:*****:***:* .:. .. :.**:**:*::.**:: :** *.. .*:.:*:. ::.::.** * *** : :*::**: .:**.:* : ****:. *..**.. **::**::********:: *:. .* ::....***::***:*:* : : *. . . : * .. *:** * * ::. . :: . : *:..: . *::: ::*:* : . :*:* *: .:*: * : . *::: . :**: *:: .: : .**.*: *: : :::*.*: :: * * *:. . .:.:. * : :. * : *: *.*... : .:: : *: :*::*:..: .:. . * :::** :.: . :. :: ::::* ::::. : *. :: : :.. * * . :: . . .. : *: : :.:* . :. :* . . :: : :. : : : .* ::: . .: :.*.:: . : :* : . . .. .:* ** .. ** **.***::* : .* ::. : * :*. : ** * * .::*: :. :. .* : *: *:: : ** ::.:** . * : : .: : :: : :. : * : ::::* ::::**.:: :..::* * ..: *: : *.: : . . : :*.. .:.:: ** :*:: :.*: ::*:: .. *:::. :: ..* :: : : :: :*:: * * :..: *:** **: :.* : :: *: * *: : . :: * ::: :*: : . : : ... * **:*:: .:: :*:.: .* :: . *::* ..*: * : : :* :..:* :.*::*:.****:** *::: : *** :. *::: :: **: : : ::* * :: .. : : : .: *. :: ::::*: ***::* ..:. :. . :. :..* :.: :::: **.: :: :: *.:*.** .:* * ** **: : * ** : : : ** ..* : : **:: . :.: : * . :** *:*..:. * * ..:::**:: .:: *::*:* : **** :: .: *.*:.*: :* : * * * * :*:. . * * ::::. .* :* :... :* . : .: . ** .:::***:*: :* : : ::*: * :.*.**.:* ::.::******:.:*: :**:* .*: : ::::. *:: *: . *:****** *:*****.:* ***. **:* * .*.**:*:**::*::*::::.:: * .: :..:*: . *. .* .* * . : :... : : *: * . :: . * : ::: . . .* :. *:. * * ", "identical_positions": 428, "similar_positions": 723, "identity": "20.08%" }, { "cls_id": "homologset.agr.FB:FBgn0002521", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TTC2-1", "uniprot_id": "TYY2_MOUSE", "id": "Q3TTC2-1", "name": "Transcription factor YY2", "aln": "MASETEKLLCLNTESAEIPADFVELLPPDN--IGDIEAVSLETSVGQTIEVYGDVGVDWAHG---------------------SQYHSPVIALQP---------LVGSSLSSRDHDKEMFVVQTREEEVVGYQDSDNLLFSPEFGSQMVLPVNED-----DYLQPTTASFTGFLAAENG-------QGELSPYEGNLCGLTTFIEAG--AEESVNADLGDK---QWEQK--QIDGLDGEFPFTMWDDVNEK----EDPIAEEQAGE-SPPDYSEYMTGKKFPPEG--------IPGIDLSDPKQLAEFT----------------------------SMRPKKPK-GDFPRP-------------------IACSHKGCEKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C6P6-1", "uniprot_id": "TYY2_RAT", "id": "P0C6P6-1", "name": "Transcription factor YY2", "aln": "MASDTEKLMCLTTENAEIPADFVELQPLD-----EIETVSLETNVSQTIEVYGDVGVDWAHG---------------------GHYHSPLIALQP---------LAGSNLSNGDHDQEMIIVQTR-EEVVDYQDSDNLLLGTEFESQMVLPVNED-----DYLQPTTATFSGFMAAENG-------QDELSPYGGNLCGLTTIIEAG--AEEGVNPDLGDK---QWEQKQIQIDGLDGEFPFAMWEDNNLK----EDPVAEEEAGE-STPDYSEYMTGKKFPPEG--------IPGIDLSDPKQLAEFT----------------------------SMKPKKPK-GDFPRP-------------------VACSHKGCGKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25490-1", "uniprot_id": "TYY1_HUMAN", "id": "P25490-1", "name": "Transcriptional repressor protein YY1", "aln": "MASG--DTLYIATDGSEMPAEIVELHEIE---VETIPVETIETTVVGEEEEEDDDDEDGGGGDHGGGGG-HGHAG-HHHHHHHHHHHPPMIALQP---------LVTDDPTQVHHHQEVILVQTR-EEVVGGDDSDGLRAEDGFEDQILIPVPAPAGGDDDYIEQTLVTVAAAGKSGGGGSSSS-GGGRVKKGGGKKSGKKSYLSGGAGAAGGGGADPGNK---KWEQKQVQIKTLEGEFSVTMWSSDEKKDIDHETVVEEQIIGENSPPDYSEYMTGKKLPPGG--------IPGIDLSDPKQLAEFA----------------------------RMKPRKIKEDDAPRT-------------------IACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00899-1", "uniprot_id": "TYY1_MOUSE", "id": "Q00899-1", "name": "Transcriptional repressor protein YY1", "aln": "MASG--DTLYIATDGSEMPAEIVELHEIE---VETIPVETIETTVVGEEEEEDDDDEDGGGGDHGGGGGGHGHAGHHHHHHHHHHHHPPMIALQP---------LVTDDPTQVHHHQEVILVQTR-EEVVGGDDSDGLRAEDGFEDQILIPVPAPAGGDDDYIEQTLVTVAAAGKSGGG--ASS-GGGRVKKGGGKKSGKKSYLGGGAGAAGGGGADPGNK---KWEQKQVQIKTLEGEFSVTMWSSDEKKDIDHETVVEEQIIGENSPPDYSEYMTGKKLPPGG--------IPGIDLSDPKQLAEFA----------------------------RMKPRKIKEDDAPRT-------------------IACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BHN0-1", "uniprot_id": "A0A8M2BHN0_DANRE", "id": "A0A8M2BHN0-1", "name": "", "aln": "MASG--ETLYIEAEGAAVPAELVELQEIE---VETI-----ETTVIGGEDEDEDEEE------------------------------PAMIALQP---------LHTGD-----GEPGVILLQTR-EEVVG---EDAELRGDAFEEQILIPVPTP-GADAQYIGQTLLTVA--GRSSGG------RAGRRAAAGGKKTGKKSYLS---------AAESSGR---KWEQKQVQIKTLEGEFSVTMWASDDKKELEHE--VEEHIIGENSPPDYSEYMTGKKLPPGG--------IPGIDLSDPKQLAEFASPF-----------------SNSGGQFSRMKPKKIKEDDAPRT-------------------IACPHKGCSKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O15391-1", "uniprot_id": "TYY2_HUMAN", "id": "O15391-1", "name": "Transcription factor YY2", "aln": "MASN--EDFSITQD-LEIPADIVELHDIN---VEPLPMEDIPTESVQYEDVDG----NWIYG---------------------GHNHPPLMVLQP---------LFTNTG-YGDHDQEMLMLQTQ-EEVVGYCDSDNQ-LGNDLEDQLALPDSIE----DEHFQMTLASLSASAASTST----S-TQSRSKKPSKKPSGKSATSTEAN--PAGSSSSLGTR---KWEQKQMQVKTLEGEFSVTMWSPNDNND---QGAVGEGQAEN--PPDYSEYLKGKKLPPGG--------LPGIDLSDPKQLAEFT----------------------------KVKPKRSK-GEPPKT-------------------VPCSYSGCEKMFRDYAAMRKHLHIHGPRVHVCAECGKAFLESSKLRRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHLRIHTGDKPFVCPFDVCNRKFAQSTNLKTHILTHVKTKNNP---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8ST83-1", "uniprot_id": "PHO_DROME", "id": "Q8ST83-1", "name": "Polycomb protein PHO", "aln": "MAYERFGIILQSEQYDEDIGNTKVNQKMNEGNHYDLHRKNAFDRIIHSESKKGDNVINYNIHEN-------------DKIKAADNIFSSKLKMNPNMSYEMNINCFKNIGYGENQETSKVLTNSLSNNDINTEESGVVDKNSPFLTLGTTILNSN--GKSRRWEQKLVHIKTMEGEFSVTMWASGISDDEYSGSDQIVGASDLLKGKEEFGIDGFTSQQNKEYQKMESKFTNAQTLEMPHPISSVQIMDHLIKERGNLSQENNISERILSKTTLSFEEPILLPDSSSIELVNETAAMTINNHRTLSNHTGNTGDLHALPSSVPFRIGLHEGQVNDCLSTISQSTHQDNTDSTGCGEMNLSEVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTHAKAKRNTSISGKSGCSNAESNSQSEDTSANYVKVELQDSVTENHVPFVVYAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : .: : : . .. : ::* . . .: :: :: :. .. : . . . . : * . .. : : *.* : . *: ...: : * : .. : : : * . ..: :.: : *::.: .: : .: . :.*.:.** * *:* :******* ***************:*****:***********:********:***********:******:*:***** **:*********:*****.* *.: ", "identical_positions": 103, "similar_positions": 87, "identity": "19.25%" }, { "cls_id": "homologset.agr.FB:FBgn0002522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08656-1", "uniprot_id": "HXA1_RAT", "id": "O08656-1", "name": "Homeobox protein Hox-A1", "aln": "-------------MDNARLNSFLEYP-ILGSGDSG---TC------------SARVYSSDHGITTFQS---CAVSANSCGGDDRFLGGRG---VQITSP--HHHHHHHHHPQPATYQTS--GNLGVSYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAPAVYSGNLSSP----------------------------------------------------------------------------------------------------------MVQHHHHHQGYAGGTVGSP---QYIHHSYGQ--EHQSLALAT-YNNSLSPLHASHQEACR-------------------------------------SPASETSSPAQTFDWMKVKRNPPKT-----------GKVGEYGYVGQPNAVR---------------------------------------------------------------------------TNFTTKQLTELEKEFHFNKYLTRAR-SEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPMSPATPPGSDEKTEESSEKSSSSPSAPSPASSTSDTLTTSH----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09022-1", "uniprot_id": "HXA1_MOUSE", "id": "P09022-1", "name": "Homeobox protein Hox-A1", "aln": "------------------MNSFLEYP-ILGSGDSG---TC------------SARAYPSDHGITTFQS---CAVSANSCGGDDRFLVGRG---VQISSPHHHHHHHHHHHPQTATYQTS--GNLGISYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAPAVYSGNLSTP----------------------------------------------------------------------------------------------------------MVQHHHHHQGYAGGTVGSP---QYIHHSYGQ--EQQTLALAT-YNNSLSPLHASHQEACR-------------------------------------SPASETSSPAQTFDWMKVKRNPPKT-----------GKVGEYGYVGQPNAVR---------------------------------------------------------------------------TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGSDEKTEESSEKSSPSPSAPSPASSTSDTLTTSH----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49639-1", "uniprot_id": "HXA1_HUMAN", "id": "P49639-1", "name": "Homeobox protein Hox-A1", "aln": "-------------MDNARMNSFLEYP-ILSSGDSG---TC------------SARAYPSDHRITTFQS---CAVSANSCGGDDRFLVGRG---VQIGSP-HHHHHHHHRHPQPATYQTS--GNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSP----------------------------------------------------------------------------------------------------------MVQHHHHHQGYAGGAVGSP---QYIHHSYGQ--EHQSLALAT-YNNSLSPLHASHQEACR-------------------------------------SPASETSSPAQTFDWMKVKRNPPKT-----------GKVGEYGYLGQPNAVR---------------------------------------------------------------------------TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SI1-1", "uniprot_id": "HXA1A_DANRE", "id": "Q98SI1-1", "name": "Homeobox protein Hox-A1a", "aln": "------------------MSTFLDFSSISGGGDGGSGGSC------------SVRAFHGDHGLSTFQSS--CAVRLNSCSGDERFMSN-------ISSQ----DVINSQPQQAGSYQSP--GTLSITY---SAHPSYGTQSFCTGYNHYALNQDVESSVSFPQCGPLVYSGNISST----------------------------------------------------------------------------------------------------------VVQHRHHRHGYSSGNVHLHGQFQYGSATYGNSSDQANLTFVAGCSNPLSPLHVPHHDACC-------------------------------------SPLSDGVPTGQTFDWMKVKRNPPKT-----------GKAGEYGFGGQPNTVR---------------------------------------------------------------------------TNFSTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPKSLSEQKDGLEKTEDASEKSPSAPSTPSP-SPTVEAYSSN-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90423-1", "uniprot_id": "HXB1B_DANRE", "id": "Q90423-1", "name": "Homeobox protein Hox-B1b", "aln": "------------------MNSYLDYT-IYNRGSNTYS-----------------SKVGCFPVEQEYLP--SACASTNSYIPEGRP-VGGN---TFTSAP------HETHGTSYAQIQSQ-PFHLNVDMG-KTGHSNFCKQTRPPHSDYGHQHVLTQADDHMRLQSPGFSVVNMGAN----------------------------------------------------------------------------------------------------------IGTYSESNC-RPGSVSASH-----YQS-YAY-GEPEPHGY--GSFSKYQVSPDSD------------------------------------------SDSKTNIKQAPTFDWMKVKRNPPKT-----------VKVAEYGIHGQQNIIR---------------------------------------------------------------------------TNFTTKQLTELEKEFHFNKYLTRARRVEVAATLELNETQVKIWFQNRRMKQKKREKEG---TAPVIKRVTLCSSGQNADHSTSSSPGASPTSDSSTAI--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O42366-1", "uniprot_id": "HXB1A_DANRE", "id": "O42366-1", "name": "Homeobox protein Hox-B1a", "aln": "------------------MNSFLEYT-ICNRGTNAYS-----------------PKAGYHHLDQAFPGPFHTGHASDSYNADGRLYVGGSNQPPTAAAQ------HQHQNGIYAHHQHQNQTGMGLTYG-GTGTTSYGTQACANSDYAQHQYFINPEQDGMYYHSSGFSTSNASPH----------------------------------------------------------------------------------------------------------YGSMAGAYCGAQGAVPAAP-----YQH-HGCEGQDHQRAYSQGTYADLSASQGTE------------------------------------------KDTDQ-PPPGKTFDWMKVKRNPPKT-----------GKVAEYGL-GPQNTIR---------------------------------------------------------------------------TNFTTKQLTELEKEFHFSKYLTRARRVEIAATLELNETQVKIWFQNRRMKQKKREKEG---LAPASSTSSKDLEDQ-SDHSTSTSPEASPSPDS------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V737-1", "uniprot_id": "G3V737_RAT", "id": "G3V737-1", "name": "Homeobox protein Hox-B1", "aln": "-------------MDYNRMNSFLEYP-LCNRGPSAY------------------------SAPTSFPP--SSAPAVDSYAGESRY--GGG-----LPSS------ALQQNSGYPVQQPP--SSLGVSFP-SSAPSGYAPAACNPSYGPSQYYSMGQSEG----DGGYFHPSSYGAQ----------------------------------------------------------------------------------------------------------LGGLPDSYG--AGGVGSGP-----YPPPQPPYGTEQTSNFASAY-DLLSEDKESS------------------------------------------CSSEPSSLTARTFDWMKVKRNPPKT-----------AKVSELGL-GTPGGLR---------------------------------------------------------------------------TNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGR-VPAGPPGCPKEAAGEASDQSACTSPEASPSSITS-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17919-1", "uniprot_id": "HXB1_MOUSE", "id": "P17919-1", "name": "Homeobox protein Hox-B1", "aln": "-------------MDYNRMSSFLEYP-LCNRGPSAY------------------------SAPTSFPP--CSAPAVDSYAGESRY--GGG-----LPSS------ALQQNSGYPVQQPP--SSLGVSFP-SPAPSGYAPAACNPSYGPSQYYSVGQSEG----DGSYFHPSSYGAQ----------------------------------------------------------------------------------------------------------LGGLPDSYG--AGGVGSGP-----YPPPQPPYGTEQTATFASAY-DLLSEDKESP------------------------------------------CSSEPSTLTPRTFDWMKVKRNPPKT-----------AKVSELGL-GAPGGLR---------------------------------------------------------------------------TNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGR-MPAGPPGCPKEAAGDASDQSACTSPEASPSSITS-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14653-1", "uniprot_id": "HXB1_HUMAN", "id": "P14653-1", "name": "Homeobox protein Hox-B1", "aln": "-------------MDYNRMNSFLEYP-LCNRGPSAYS---------------------AHSAPTSFPP--SSAQAVDSYASEGRY--GGG-----LSSP------AFQQNSGYPAQQPP--STLGVPFP-SSAPSGYAPAACSPSYGPSQYYPLGQSEG----DGGYFHPSSYGAQ----------------------------------------------------------------------------------------------------------LGGLSDGYG--AGGAGPGP-----YPPQHPPYGNEQTASFAPAYADLLSEDKETP------------------------------------------CPSEPNTPTARTFDWMKVKRNPPKT-----------AKVSEPGL-GSPSGLR---------------------------------------------------------------------------TNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREEGR-VPPAPPGCPKEAAGDASDQSTCTSPEASPSSVTS-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4ACE4-1", "uniprot_id": "D4ACE4_RAT", "id": "D4ACE4-1", "name": "Homeobox protein Hox-D1", "aln": "------------------MSSYLEYVSCAAGGGSGGVG----------------------GDVLGFAP-KFCRADARPVALQPAFPLGSGDGAFVSCLP--LAAARPTPSPPVAPAQPPGPQPAASRYAPCTLEGAYERGAAPASAA---EYGFLGSGPAFDFPGALGRAADDSGP----------------------------------------------------------------------------------------------------------HVHYATSAVFSSGGSFLLSGQVDFAAFAEPGPFPACLKEPADGHPGPFQTVSPAPGACPKPA-----------------------------------SPTSGLPAAHSTFEWMKVKRNAPKK-----------SKLSEYGATSPSSAIR---------------------------------------------------------------------------TNFSTKQLTELEKEFHFNKYLTRARRMEIANCLQLNDTQVKIWFQNRRMKQKKREREGLLATAASVASLQLPGSETSPIKSGRNLGSPSQAQEPS-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01822-1", "uniprot_id": "HXD1_MOUSE", "id": "Q01822-1", "name": "Homeobox protein Hox-D1", "aln": "------------------MSSYLEYVSCAAGGGSGGVG----------------------GDVLGFAP-KFCRADARPVALQPAFPLGSGDGAFVSCLP--LATARPTPSPPAGPAQSPVPQPAAPRYAPCTLEGAYERGAAPASAA---EYGFLGSGPAFDFPGALGRAADEGGA----------------------------------------------------------------------------------------------------------HVHYATSAVFSGGGSFLLSGQVDFAAFGEPGPFPACLKEPADGHPGPFQTVSPAPGACPKPA-----------------------------------SPTSSLPAAHSTFEWMKVKRNAPKK-----------SKLSEYGATSPPSAIR---------------------------------------------------------------------------TNFSTKQLTELEKEFHFNKYLTRARRIEIANCLQLNDTQVKIWFQNRRMKQKKREREGLLATAASVASIKLPRSETSPIKSGRNLGSPSQAQEPS-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZZ0-1", "uniprot_id": "HXD1_HUMAN", "id": "Q9GZZ0-1", "name": "Homeobox protein Hox-D1", "aln": "------------------MSSYLEYVSCSS---SGGVG----------------------GDVLSLAP-KFCRSDARPVALQPAFPLGNGDGAFVSCLP--LAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGS----------------------------------------------------------------------------------------------------------HVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSV-----------------------------------SPASGLPAAFSTFEWMKVKRNASKK-----------GKLAEYGAASPSSAIR---------------------------------------------------------------------------TNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEPS-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10105-2", "uniprot_id": "LAB_DROME", "id": "P10105-2", "name": "Homeotic protein labial", "aln": "MMDVSSMYGNHPHHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKL-PASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTSKQS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q98SH9-1", "uniprot_id": "HXC1A_DANRE", "id": "Q98SH9-1", "name": "Homeobox protein Hox-C1a", "aln": "------------------MNSYHGFRDTTSLFIKGYHATG-------------------------------VMRLHQDHGSTADFPSRED---------------VNNEADFLQYHFTNLCATATGACSKPCEDPGRANSTRPPFPQNQDFYRPVHPNRPQVPSFQSCREQGLSRKG---------------------------------------------------------------------------------------------------------FSPSSDTFRTFSSAHCELG---------PVNNTQTEVRTYDGPVRHSAVEDDNTGHGALN--------------------------------------TLNETLHSGKTFEWMRVRRNQSRAAKIQLGKCSDRELKTNHGRDSDEDTSSGGS-----------------------------------------------------------------------RTNFTTKQLTELEKEFHFNKYLTRARRIEIANPLQLSETQVKIWFQNRRMKQKKMLREGLAQGLMLISGCD----EDSKKSDTCSSPD-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : . . *:.**:::** .: : . . ***:.:***********.:**:*** *:* *.*.:**************** :* ", "identical_positions": 45, "similar_positions": 27, "identity": "7.14%" }, { "cls_id": "homologset.agr.FB:FBgn0002524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V0-1", "uniprot_id": "D4A9V0_RAT", "id": "D4A9V0-1", "name": "serine C-palmitoyltransferase", "aln": "-----------------------------------------------------------MANPRDSAVTNGTLRNPKTQPGKRQSTDCVKNGISK--EAQQNRKAEEDDKLVFKP-YPEPPLYVFVFTYMGYGIGMLFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYTRNLYMRIRDSWSHTVCSVPVPNFDIMEKVTDDYNWTFRHTGKVIKNVINMASYNYLGLASKYNESMEKVKDTIEKYGVGVASTRNEMGSLDIHNELEDLMAKFLNVEAVMVFGMGFATNSTNIPIFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNIQNLEKLLREAIIRGQPRTG-RAWKKILILVEGVYSMEGSIVNLPQIVALKKKYKAYLYMDEAHSIGCTGTMGQGIRELFGLAPEDIDIYMGTFTKSFAASGGYIAGKKEIVDYVRVQSHSATYATSMSPVVAAQIIRSLKIMMGYEGNFGGVQRIQQLRENIKYFRRRLIEMGFIIYGNDYSPVVPVLLYMPAKVSAFGRLLLKKKIAVVVVGFPATSLPEGRARFSLSSAHTREMLDTVLEVVDKIGDLLNVKYFPYK--KSGRAVLYNKENFDNEASFEEKSSEPEA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG54-1", "uniprot_id": "SPTC3_MOUSE", "id": "Q8BG54-1", "name": "Serine palmitoyltransferase 3", "aln": "-----------------------------------------------------------MANLNDSAVTNGTLHNPKTQQGKRQSTGCVKNGISK--EAQQNRKAYAEDKPVFEP-YQEAPLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGKYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTG-RAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKYFPLK--KSGRAILYNKEGFDNEASFEEMHSEPEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUV7-1", "uniprot_id": "SPTC3_HUMAN", "id": "Q9NUV7-1", "name": "Serine palmitoyltransferase 3", "aln": "-----------------------------------------------------------MANPGGGAVCNGKLHNHKKQSNGSQSRNCTKNGIVK--EAQQNGKPHFYDKLIVES-FEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTR-RAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSRHK--KSARPELYDETSFELED------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9N3-1", "uniprot_id": "A0A8M9Q9N3_DANRE", "id": "A0A8M9Q9N3-1", "name": "serine C-palmitoyltransferase", "aln": "-----------------------------------------------------------MIRTEELHSCNGTLKSRSGQ--KQTENYTLKNGYHKNEKVQKNGNGFHQPRVRGEDSFEEAPMYVAVLTYMGYGIVILFGYFRDFLRAVGLEKCHQAQEREEQKDFVPLYQDFENFYKRNLYMRVRDNWNRPICSLPGPVFDLMERVSDDYNWTFRLTGRTIENVINMGSYNYLGFAENNVDFLKTVAEKTRQYGVGVCSTRQELGNFSIHEELEHLVADFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMQSLEKLLKEAICSGQPRTH-RSWKKILIMVEGIYSMEGSLVRLPEIIALKKKYKAYLYLDEAHSIGAVGPTGRGVTEHFGVDPKEIDVLMGTFTKSFGATGGYIAGKKELVDYLRCHSHSAVYATAMSPPVVEQIIRAIKCIMGVDGTTEGQRRVRQLAENTHYFRSRLKEMGFIIYGNKDSPVIPLLLYQPGKVGAFSRAMLKRKIGVVVVGFPATTITEARARFCVSAAHTRDMLNKVLQSLDELGDYIRVKFSRHR--RPYRPELYNVTNFGLDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97363-1", "uniprot_id": "SPTC2_MOUSE", "id": "P97363-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRS--STATVAAAGQIHHVTENGGLYKRPFNEA-FEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR-RPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRL-VPLLDRPFDETTYEETED-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B7D2-1", "uniprot_id": "SPTC2_RAT", "id": "Q3B7D2-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRS--STATIAAAGQIHHITENGGLYKRPFNEA-FEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKTYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAALTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR-RPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRP-LPLLDRPFDETTYEETED-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15270-1", "uniprot_id": "SPTC2_HUMAN", "id": "O15270-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFNEA-FEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR-RPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRL-VPLLDRPFDETTYEETED-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N5Y9-1", "uniprot_id": "A0A8M1N5Y9_DANRE", "id": "A0A8M1N5Y9-1", "name": "serine C-palmitoyltransferase", "aln": "------------------------------------------------------MTESAGTKTEDCHAANG-VKPG--RNGMVKNHHHHLQYQKQEKVYHAACNGELYSRPFIES-FEETPMLVAVLTYMGYGILTIFGYLRDFMREWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDSWNRPICSVPGAKFDLVERSSNDYNWTFEYTGRVVKDVINLGSYNYLGFAENTGSCATAAGEVTVKFGVGVASTRQEMGNLDRHEKLEKLVASFLRVESAMAFGMGFATNSMNIPALAGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTH-RPWKKILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPGGRGVVEYFGLDPRDVDIMMGTFTKSFGAAGGYIGGRKDLIDYLRTHSHSAVYASSMSAPVVEQIITSMKCIMGEDGTTIGRSRIQRLAENTVYFRRRLREMGFIIYGNNDSPVVPMMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCISAAHSKEMLDRALDVISEVGDLLQLKYSRHKV-LPSLDRPFDETTYEENEE-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3F2-1", "uniprot_id": "Q9V3F2_DROME", "id": "Q9V3F2-1", "name": "serine C-palmitoyltransferase", "aln": "MGNFDGDSGTVFEQSYATTNGNGKVPNGNGAADLSAPEKQELLRKFSAPAYTEIRTRRCQPKPANDAQSPSSINYHPEKKSIPNGHASILDQESK--PNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVP-----KVATEK-GRDGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYSRKP--RDPNPVIY---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40970-1", "uniprot_id": "LCB2_YEAST", "id": "P40970-1", "name": "Serine palmitoyltransferase 2", "aln": "-----------------------------------------------------------MSTPANYTRVPLCEPEELPDDIQKENEYGTLD-----SPGHLYQVKSRHGKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQK--NKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSG-AVYPCMNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTN-RPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * :**:.: : ::*:..::: : : :.. .. :. **.** * : *: * :.:. . * . :: :.: . * :* :*:.***:**:* . . . ..* ::* . : * * * :: * .: :.**:.**: : : . .*::*** **:*: * ****:. : ***.: .**::::: : *:* . :.*.*::* .**::****:: .*.::: ******.**::*****:*. *. *:*: : *.: *.::*: ********..:***:.. : ::* :* . : *: ::.. : * : ::: * * :::: * *:* * .:*.* ** :.*:*:::* .*: *. * : :.*..* ..:***.: *.* **.:*:: ::: :: * :.::.* : :* : ", "identical_positions": 124, "similar_positions": 183, "identity": "19.71%" }, { "cls_id": "homologset.agr.FB:FBgn0002525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLC1-1", "uniprot_id": "D3ZLC1_RAT", "id": "D3ZLC1-1", "name": "", "aln": "--------MSAPDPGSSAD---PPAAATAMASLPPRAG-SATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDKLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEAKKSAKKREGELTVARGRVKDLESLFHRSEAELAAALGDKHVLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENHCQSLQEELAFSKSVFEEEVQETRRRHERHLVEVDSSRQQEYDFKIAQALEELRSQHDEQVRLYRLELEQTYQAKLDNTKLISDQNDKAARAAREELKEARMRVESLSYQLSGLQKQASAAEDHIRELEEALAGERDKFRNMLDAKEQEMAEVRDAMQQQLAEYQELLDIKLALDMEICSYRKLLEGEEERLKLSPSPSSRVTISLATSSSSSSSSSGVGMSLGRGRSKRQRLETEDTPGS-PSSASSVSSGS---RLAQQAGATGVVNIDEVDLEGRFVRLKNSSDKVSMGQGGRTGTPFLVAGGSKACLGCRINLWGTGGSRNRFWRVRTSPTSSHPSMSCEPARRSRCGQLAQGLHTAPHQPLCGRTRAAGGLGRTSAPSWSMRTARRWPCRLQSRHLSRGT---RAGRRRK--RQRQSLVKRTFSTSRGTQGLPQGAAG-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21619-1", "uniprot_id": "LMNB2_MOUSE", "id": "P21619-1", "name": "Lamin-B2", "aln": "-----------------------------MASLPPHAG-PATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEDLRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQASAAENHIHELEEALAGERDKFRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPSPSSRITISRATSSSSSS--SGVGMSVGQGRGKRRRLETEDTSGS-PSRASRVSSGS---RLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKR--QVLEGEDIAYKFTPKYVLRAGQTVTVWAAGAGATHSPPSTLVWKSQTNWG--PGESFRTALVS-------ADGEEVAVKAAKHSSVQGRENGEEEEEEEAEFGE---EDLFHQQ--GDPR-------TTSRGCRLM-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03252-1", "uniprot_id": "LMNB2_HUMAN", "id": "Q03252-1", "name": "Lamin-B2", "aln": "--------MSPPSPGRRREQRRPRAAATMATPLPGRAGGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLKISEKEEVTTREVSGIKALYESELADARRVLDETARERARLQIEIGKLRAELDEVNKSAKKREGELTVAQGRVKDLESLFHRSEVELAAALSDKRGLESDVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELDFRKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYKLELEQTYQAKLDSAKLSSDQNDKAASAAREELKEARMRLESLSYQLSGLQKQASAAEDRIRELEEAMAGERDKFRKMLDAKEQEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRATSSSSGS----LSATGRLGRSKRKRLEVEEPLGSGPSVLGTGTGGSGGFHLAQQASASGSVSIEEIDLEGKFVQLKNNSDKDQSLGNWRIKR--QVLEGEEIAYKFTPKYILRAGQMVTVWAAGAGVAHSPPSTLVWKGQSSWG--TGESFRTVLVN-------ADGEEVAMRTVKKSSVMRENENGEEEEEEAEFGE---EDLFHQQ--GDPR-------TTSRGCYVM-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70615-1", "uniprot_id": "LMNB1_RAT", "id": "P70615-1", "name": "Lamin-B1", "aln": "---------------------MATATPVQQ-RAGSRASAPATPFSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----ISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIR---KIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWG--TGEDVKVVLKN-------SQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLE---EERFHQQ--GTPR-------ASNKSCAIM-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14733-1", "uniprot_id": "LMNB1_MOUSE", "id": "P14733-1", "name": "Lamin-B1", "aln": "---------------------MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----ISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIR---KIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWG--TGEDVKVILKN-------SQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVAVE---EERFHQQ--GAPR-------ASNKSCAIM-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20700-1", "uniprot_id": "LMNB1_HUMAN", "id": "P20700-1", "name": "Lamin-B1", "aln": "---------------------MATATPVPP-RMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----ISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIR---KIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWG--TGEDVKVILKN-------SQGEEVAQRSTVFKTTIPEEEEEEEE-AAGVVVE---EELFHQQ--GTPR-------ASNRSCAIM-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHC4-1", "uniprot_id": "F1QHC4_DANRE", "id": "F1QHC4-1", "name": "", "aln": "---------------------MASAACTPAGQQSLSRGTSSTPLSPARISRLQEKEELQQLNDRLAAYIDTVRSLESENSVLQIQIREREDVRNRELTGLRTLYETELADARKALDDTARERARLQIELGKIKSEQEQLQHTYAKKDADLTSSQNRLKDVEALLNAKEAALNTAVSERKTLENTLSDLQIRVQELEGGLISAKKQLSDETLLRVDLENRCQSLMEELEFRKNMFEEEIKDTRRRHETRLVEVDSGRQMEYEFKLAQALTDMRQQHDEQVKLYKEEMEQTYVSKLENIRLSSEMNSSSASMAREELRESTLRVESLAGQLANLQKEARAWQDRINELEGALSHEKDLSRRLLAEKEREIAEIRAKMQQQLDEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----IAHSASATGNVSIDELDVDGKFIRLHNNSEQDQPMAGFQLTR---TIGEVTATYKFTAKYNLKAGQKVTIWASNAGISSNPPADLIWKNQPSWG--TGENIKVALLS-------PAGEEVAVRSTVFKTAVEDEDDDEEEEKEAEVIE---EHFYHQQ--GDPR-------AAKRGCLIM-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48679-1", "uniprot_id": "LMNA_RAT", "id": "P48679-1", "name": "Prelamin-A/C", "aln": "-----------------------METPSQRRPTRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQS-------QGGGSVTKKRKLESSESRSS----------------FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKR--QNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWG--CGTSLRTALIN-------ATGEEVAMRKLVRSLTMVEDNDDEEEDGDELLHH---HRGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKA-ASGSGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSSQNCSIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48678-1", "uniprot_id": "LMNA_MOUSE", "id": "P48678-1", "name": "Prelamin-A/C", "aln": "-----------------------METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQS-------QGGGSVTKKRKLESSESRSS----------------FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRR--QNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWG--CGSSLRTALIN-------STGEEVAMRKLVRSLTMVEDNEDDDEDGEELLHH---HRGSHCSGSGDPAEYNLRSRTVLCGTCGQPADKA-AGGAGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRSQSSQNCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02545-1", "uniprot_id": "LMNA_HUMAN", "id": "P02545-1", "name": "Prelamin-A/C", "aln": "-----------------------METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQT-------QGGGSVTKKRKLESTESRSS----------------FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKR--QNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWG--CGNSLRTALIN-------STGEEVAMRKLVRSVTVVED--DEDEDGDDLLHH---HHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08928-1", "uniprot_id": "LMNB_DROME", "id": "P08928-1", "name": "Lamin", "aln": "MSSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHS-------------VADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQR-LINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVS---ADNTRTILLN-------SEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTAVDGNEQLYHQQ--GDPQ-------QSNEKCAIM-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*:**:* :*: ** :*::****** *** ** ** ** * :.: .:. ** :.:: :*:** ::*: **..*::**: :::: : * .: *: : :. .:: *: : : * .::: *: : : .: . . ::*:* .* * :** ** *:: *:* * ..:..:*:.:::* :: . *:*. . *:: :: ::* ::* *:: *:. : *::. * *:: : : . . . : : .: :*:::* :: *:: ::.:** : ::: . : *:*: .:* * *** :*::*:*:*::**:** :* *** *** **.::*:..: . : * . ::: : . * : :.* * :.*:* :*:*::* *...: . . . .* : : . *: : . . :. . . * . . : . ", "identical_positions": 107, "similar_positions": 189, "identity": "14.74%" }, { "cls_id": "homologset.agr.FB:FBgn0002526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAN8-1", "uniprot_id": "F1MAN8_RAT", "id": "F1MAN8-1", "name": "Laminin subunit alpha-5", "aln": "MAKRGGQLCVGCAPGARGPRSLAPLP-LLLLAGLALVGEARI--PGGDGFSLHPPYFNLAEGARITASATCGEEAPTRSASRPTEDLYCKLVGG-PVAGGDPNQTIQGQYCDICIAANSNKAHPVSNAIDGTERWWQSPPLSRGPEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGRPGARNFSYSPVLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADVCDAKDPSDPFRLQ-CACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYDCYYDPEVDRRNASQNLDNVYQGGGVCLDCQHHTTGINCERCVPGFYRAPDQPLDSPHVCQPCDCESDFTDGTCEDLTGRCYCRPNFTGERCSACAEGYVDFPHCYPLPSFPHNDTG-EQVLPAGQIVNCDCNAAGTQGNACRKDPRLGRCVCKPNFQGNHCELCAPGFYGPSCHPCQCSSPGVANGLCDPESGQCTCRTGFEGDKCDHCALGYFHFPLCQLCGCSPAGTLPQGCD-ESGHCQCRPGFDGPHCDRCLPGYHGYPDCHACACDPRGSLDQQCGAGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSMHTTCDPTTGQCRCRPRVTGLRCDMCVPGAYNFPYCEAGS--CHPAGLAPANPALPEAQA--PCTCRAHVEGPSCDRCKPGYWGLSSSNPEGCTRCSCDPRGTLGGVTECQ-GNGQCFCKAHVCGKTCAACKDGFFGLDHADYYGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPSCSEPAKDHYLPDLHHIRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAHMTAIQPRIVARLNVT--SPDLFRLVFRYVNRGSTSVNGQVSVREEGKFSSCTNCTEQSQPVAFPPSTEPAFVTVPQRGFGEP--FVLNPGTWALLVEAEG-VLLDYVVLLPSTYYEAALLQHRVTEACTYHPSALHPTENCLLYAHLPLDGFPSAAGTEALCRHDNSLPRPCPTEQLSPLHPPLATCAGSDVDIQLEMAVPRPGRYALVVEYVSEYSHQEMGVAVHTPQRAP-QQGMIDLHPCPYSSLCRGPARDTQHHLAVFHLDSEASIRLT----AEQAHFFLHSVTLIPVEEFSAEFVEPRVFCVSSHGAFNPGSAACLASRFPKPPQPIVLKDCQVLPLPPDLPLTQSQELSPGASPVGPQPRPPTAVDPNAEPTLIRHPQGTVVFTTQVPTLGRYAFLLHSYQPVHPSFPVEVLIDGGR-IWQGHANASFCPHGYGCRTLVSCEGQTMLDVTDNELAVTVRVPEGRWLWLDYILVVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSLFCRNAATSLSLFYNNGALPCGCHEVGAVGPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTCAPGFYSYPSCRPCDCHEAGTMASVCDPFTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCFCFGATERCGNSNYARHEFMDMEGWVLLSSDRQVVPHEHRPEMELLHADLR----LVADTFPELYWQAPPSYLG---------DRVSSYGGTLHYELHSETRRGDVFIPYESRPDVVLQGNQMSIAFLELAYPSPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFSQTSSTVSLRRVVLEVASEAGGGP---PASNVELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCVPCQCHGHSDRCLPGSGTCVGCQHNTEGDQCERCRPGFVSSDPSDPASPCVSCPCPLAVPSNNFADGCILR--NGRTQCLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTGACRGCLRHTTGPRCESCAPGFYGNALLPGNCTRCDCSPCGTETCDPQTGRCLCKAGVTGQRCDHCLEGHFGFEQCQGCHPCACGPAAEGSECNPQTGQCHCRPGTTGPQCLECAPGYWGLPEKGCRRCQCPRGHCDPHTGRCTCPPGLSGERCDTCSQQHQVPVPGRPGSHGIHCEVCDHCVVLLLDDLERAGALLPSIREQLRGINASSTAWARLHRLNASIADLQSKLRSPLGPHNQTAEQLQTLEQQSISLQQDTERLGSQATGVQDQAGRLLDNTESTLVRAQKLLEIVQAVSRALNELAS---QGFPGNATTPSGEQLRWALAEVERLLWDMRTRDLGAPQAVAEAELAEAQRLMARVQEQLTSFWEENQALATHIRDQLAQYESGLMDLREALNHAVNTTREADELNSRNEERLREALQWKQELSQDNATLKATLQAASLTLAHVSELLQGIDKAKEDLEHLAASLDGAWTPLLKRMQAFS-PASSKVDLVEAAEAHAQKLNQLAINLSGIIQGINQDRFIQRAVEASNAYSSILQAVQAAEDAAGHALRQASRTWEMVVQRGLAAGARQLLANS-SALVETILGHQERLGLAHGRLQAAGTQLRDVRAKKNQLAAQIQEAQAMLA-MDTSETSEKIAHAKAVAAEARDTAAHVQSQLQGMQKNVERWQSQLGGLR--GQDLSQAERDASSSVSTLEKTLPQLLAKLSHLENRGVHNASL--ALSANIGRVRKLIAQARSAANKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFYIQSPVPAPEPGENTGDRFVLYMGSR----QATGDYMGVSLRNQKVHWVYRLGEAG-----PTTLSIDENIGEQFAAVSIDRTLQFGHMSVTVEKHMVHEIKG---DTVAPGREGLLNLNPDDFVFYVGGYP--SNFTPPEPLRFPGYLGCIEMDTLNEEVVSLYNFEQAFKLTTAVDKPCARSKTTGDPWLTDGSYLDGSGFARITFEKQFS--NTKRFEQELRLVSYNGIIFFLKQENQFLCLAVQDGTLVLLYDFGSGLKRADPLQPPQALTAASKAIQVFLLAGARKRVLVRVERATVFSVDQDNELEMADAYYLGGVPPEELPPSLRRLFPSGGSVRGCIKGIKALGKYVDLKRLNTTG-ISFSCTADLLMGRTMTFHGHGFLPLALPDVAPITGEVYSGFGFRGTQDDNLLYYRTSPDGPYQVSLRGGHVTLQFMN---REVETQRVFADGAPHYVAFYSNVTRVWLYVDDQLQP--VKSREGTTPMLQLQPEEPPRLLLGGLPMSGTFHNFSGCISNVFVQRLRG----------------PQRVFDLHQNMGSVNVSVG-------------CTPAQLQTSG--------ATAQKVSRRSRQPSQD-LTCMTPWLLGTIQDAYQFGGPGPSYLQFVGVSPSHRN------------------------------------------RLHLSMLVRPHGASQGLLLYVAPLSSHSPSLVLFLNHGRFVAQTEG-PGPQLQAQSRQHSRAGQWHRVSVRWGMQQVQLVVDGSQTWSQKAPHRRVHRAEGPQHYTLFVGGL------PAGSYSSKLPVSVGFSGCMKKLQLDKRPLRAPTRMVGVTPCVSGPLEDGLFFPGSEGAVTLELPKAKMPHVSLELEVRPLAAAGLIFHLGQAHATPYVQLQLLTEQVLLRANDG-AGEFSTWVTYP-KLCDGQWHQVTVIKGRNTLRLEVDTHSNHT-TGRLPETLADSPALLHLGSPPK--SEAAWPEPPAYRGCLRKLLFNGAPVNMTASARIQGAVGMSGCPSGTLAISKQGKALTQRQANPSVFPLRWH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61001-1", "uniprot_id": "LAMA5_MOUSE", "id": "Q61001-1", "name": "Laminin subunit alpha-5", "aln": "MAKRGGQLCAGSAPGALGPRSPAPRPLLLLLAGLALVGEART--PGGDGFSLHPPYFNLAEGARITASATCGEEAPTRSVSRPTEDLYCKLVGG-PVAGGDPNQTIQGQYCDICTAANSNKAHPVSNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGRPGALNFSYSPLLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADVCDAKDPLDPFRLQ-CACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYDCYYDPEVDRRNASQNQDNVYQGGGVCLDCQHHTTGINCERCLPGFFRAPDQPLDSPHVCRPCDCESDFTDGTCEDLTGRCYCRPNFTGELCAACAEGYTDFPHCYPLPSFPHNDTR-EQVLPAGQIVNCDCNAAGTQGNACRKDPRLGRCVCKPNFRGAHCELCAPGFHGPSCHPCQCSSPGVANSLCDPESGQCMCRTGFEGDRCDHCALGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCQCRPGFDGPHCDRCLPGYHGYPDCHACACDPRGALDQQCGVGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSLHTTCDPTTGQCRCRPRVTGLHCDMCVPGAYNFPYCEAGS--CHPAGLAPANPALPETQA--PCMCRAHVEGPSCDRCKPGYWGLSASNPEGCTRCSCDPRGTLGGVTECQ-GNGQCFCKAHVCGKTCAACKDGFFGLDYADYFGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPTCSEPAKDHYLPDLHHMRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAHMMAIQPRIVARLNVT--SPDLFRLVFRYVNRGSTSVNGQISVREEGKLSSCTNCTEQSQPVAFPPSTEPAFVTVPQRGFGEP--FVLNPGIWALLVEAEG-VLLDYVVLLPSTYYEAALLQHRVTEACTYRPSALHSTENCLVYAHLPLDGFPSAAGTEALCRHDNSLPRPCPTEQLSPSHPPLATCFGSDVDIQLEMAVPQPGQYVLVVEYVGEDSHQEMGVAVHTPQRAP-QQGVLNLHPCPYSSLCRSPARDTQHHLAIFYLDSEASIRLT----AEQAHFFLHSVTLVPVEEFSTEFVEPRVFCVSSHGTFNPSSAACLASRFPKPPQPIILKDCQVLPLPPDLPLTQSQELSPGAPPEGPQPRPPTAVDPNAEPTLLRHPQGTVVFTTQVPTLGRYAFLLHGYQPVHPSFPVEVLINGGR-IWQGHANASFCPHGYGCRTLVLCEGQTMLDVTDNELTVTVRVPEGRWLWLDYVLIVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSPFCRNAATSLSLFYNNGALPCGCHEVGAVSPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTCAPGFYGYPSCRPCDCHEAGTMASVCDPLTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCFCFGATERCGNSNLARHEFVDMEGWVLLSSDRQVVPHEHRPEIELLHADLR----SVADTFSELYWQAPPSYLG---------DRVSSYGGTLHYELHSETQRGDIFIPYESRPDVVLQGNQMSIAFLELAYPPPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFSQTSSSVSLRRVVLEVASEAGRGP---PASNVELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCVPCQCHGHSDRCLPGSGICVGCQHNTEGDQCERCRPGFVSSDPSNPASPCVSCPCPLAVPSNNFADGCVLR--NGRTQCLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTGACRGCLRHTTGPHCERCAPGFYGNALLPGNCTRCDCSPCGTETCDPQSGRCLCKAGVTGQRCDRCLEGYFGFEQCQGCRPCACGPAAKGSECHPQSGQCHCQPGTTGPQCLECAPGYWGLPEKGCRRCQCPRGHCDPHTGHCTCPPGLSGERCDTCSQQHQVPVPGKPGGHGIHCEVCDHCVVLLLDDLERAGALLPAIREQLQGINASSAAWARLHRLNASIADLQSKLRSPPGPRYQAAQQLQTLEQQSISLQQDTERLGSQATGVQGQAGQLLDTTESTLGRAQKLLESVRAVGRALNELASRMGQGSPGDALVPSGEQLRWALAEVERLLWDMRTRDLGAQGAVAEAELAEAQRLMARVQEQLTSFWEENQSLATHIRDQLAQYESGLMDLREALNQAVNTTREAEELNSRNQERLKEALQWKQELSQDNATLKATLQAASLILGHVSELLQGIDQAKEDLEHLAASLDGAWTPLLKRMQAFS-PASSKVDLVEAAEAHAQKLNQLAINLSGIILGINQDRFIQRAVEASNAYSSILQAVQAAEDAAGQALRQASRTWEMVVQRGLAAGARQLLANS-SALEETILGHQGRLGLAQGRLQAAGIQLHNVWARKNQLAAQIQEAQAMLA-MDTSETSEKIAHAKAVAAEALSTATHVQSQLQGMQKNVERWQSQLGGLQ--GQDLSQVERDASSSVSTLEKTLPQLLAKLSRLENRGVHNASL--ALSANIGRVRKLIAQARSAASKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFHIQSPVPAPEPGKNTGDHFVLYMGSR----QATGDYMGVSLRNQKVHWVYRLGKAG-----PTTLSIDENIGEQFAAVSIDRTLQFGHMSVTVEKQMVHEIKG---DTVAPGSEGLLNLHPDDFVFYVGGYP--SNFTPPEPLRFPGYLGCIEMETLNEEVVSLYNFEQTFMLDTAVDKPCARSKATGDPWLTDGSYLDGSGFARISFEKQFS--NTKRFDQELRLVSYNGIIFFLKQESQFLCLAVQEGTLVLFYDFGSGLKKADPLQPPQALTAASKAIQVFLLAGNRKRVLVRVERATVFSVDQDNMLEMADAYYLGGVPPEQLPLSLRQLFPSGGSVRGCIKGIKALGKYVDLKRLNTTG-ISFGCTADLLVGRTMTFHGHGFLPLALPDVAPITEVVYSGFGFRGTQDNNLLYYRTSPDGPYQVSLREGHVTLRFMN---QEVETQRVFADGAPHYVAFYSNVTGVWLYVDDQLQL--VKSHERTTPMLQLQPEEPSRLLLGGLPVSGTFHNFSGCISNVFVQRLRG----------------PQRVFDLHQNMGSVNVSVG-------------CTPAQLIETSR-------ATAQKVSRRSRQPSQD-LACTTPWLPGTIQDAYQFGGPLPSYLQFVGISPSHRN------------------------------------------RLHLSMLVRPHAASQGLLLSTAPMSGRSPSLVLFLNHGHFVAQTEG-PGPRLQVQSRQHSRAGQWHRVSVRWGMQQIQLVVDGSQTWSQKALHHRVPRAERPQPYTLSVGGL------PASSYSSKLPVSVGFSGCLKKLQLDKRPLRTPTQMVGVTPCVSGPLEDGLFFPGSEGVVTLELPKAKMPYVSLELEMRPLAAAGLIFHLGQALATPYMQLKVLTEQVLLQANDG-AGEFSTWVTYP-KLCDGRWHRVAVIMGRDTLRLEVDTQSNHT-TGRLPESLAGSPALLHLGSLPK--SSTARPELPAYRGCLRKLLINGAPVNVTASVQIQGAVGMRGCPSGTLALSKQGKALTQRQAKPSVSPLLWH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15230-1", "uniprot_id": "LAMA5_HUMAN", "id": "O15230-1", "name": "Laminin subunit alpha-5", "aln": "MAKR---LCAGSALCVRGPR--GPAP--LLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGG-PVAGGDPNQTIRGQYCDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQ-CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSS-SNDTR-EQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGS--CHPAGLAPVDPALPEAQV--PCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNLT--SPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAFPPSTEPAFITVPQRGFGEP--FVLNPGTWALRVEAEG-VLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQLSPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQEVGVAVHTPQRAP-QQGLLSLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLT----AEQARFFLHGVTLVPIEEFSPEFVEPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSPAGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLINAGR-VWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVPENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLG---------DRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGA---LASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSR-DDPSAPCVSCPCPLSVPSNNFAEGCVLR--GGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFS-PAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLA-MDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLR--GQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASL--ALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQG--PEPEPGQGTEDRFVMYMGSR----QATGDYMGVSLRDKKVHWVYQLGEAG-----PAVLSIDEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKG---DTVAPGAEGLLNLRPDDFVFYVGGYP--STFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSYLDGTGFARISFDSQIS--TTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELADAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTG-VSAGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGRVSLQLLR---TEVKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQ--MKPHRGPPPELQPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLG----------------PQRVFDLQQNLGSVNVSTG-------------CAPALQAQTPGLGPRGLQATARKASRRSRQPARH-PACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARHRN------------------------------------------WPSLSMHVLPR-SSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEG-LGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGL------PASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDG-AGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHT-VGPLLAAAAGAPAPLYLGGLPE--PMAVQPWPPAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1B0GWM3-1", "uniprot_id": "A0A1B0GWM3_RAT", "id": "A0A1B0GWM3-1", "name": "", "aln": "-----MAVALGWAPRSSPPLL---VLLLLLLRMSPCWSVVAQDP-PAARLSLHPPYFNLAQAAKIWATATCGERGLD--VSRPRPELFCKLVGG-PTAPGS-GHTIQGQFCDYCNSEDSRKAHPAIHAIDGSERWWQSPPLSSGTQYNKVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGNTYSPWQYFAHSRGDCLQQFGQEANMAVTRDDQVLCVTEYSRIVPLENGEIVVSLINGRPGAKHFAFSDTLREFTKATNIRLRFLRTNTLLGHLISKAERDPTVTRRYYYSIKDISVGGRCVCNGHAEACSADNPEKQFR---CKCQHHTCGDTCNRCCAGYNQRPWRPAAQDQHNECEACNCHGHAVDCYYDEAVSRQQASLNSKGVYTGGGVCIDCQHNTAGVNCEKCAKGYFRPHGVPVEALHGCIPCSCDPDRAD-ECDQGSGRCHCKPNFSGDFCETCADGYYNFPFCLRIPVFPDYTLN-PEDPMAGNIKGCDCNLEG---------------------------------------------------------------------------------------------VLPEICD-DRGRCLCRPGVEGPRCDSCRS---------------------------------------------GSYSFPICQACQCSTSGSYPVPCDPETGQCECLPGVTGRRCDRCLSGAYDFPYCQGSSSVCDPAG------TMDSSLG--YCQCKLHVTSPTCSVCKPLYWDLAKENPRGCSECQCHEAGTVSGIGECGQEDGDCSCKAHVTGDACDTCADGYFSLEKSNYFGCQGCQCDIGGALTTMCSGPSGECQCREHIEGKQCQRPESNCYFPDLHHMKYEVEGGTGPNGRDLRFGFDPLEFPEFSWRGYVPMTSVQNEVKVRLTVRKSSLSLFRIILRYINPGMEEVSGRITVYS----SRGKSDASQSKEITFPPSKEPAFVTVPGNGFADP--FSITPGTWIACIQVEG-VLLDYLVLLPRDYYEAFALQVPVTEPCAHTGSPQ---DNCLLYQHLPLTRFSCTLACEATHFLIDGERRPLAVRQPMPTHPAMVDLSGTEVELHLRLRVPQIGHYVVMLEYATEVDQLFVVDVNLKSPESA-LAGQVNIYSCKYSILCRSVVIDSLSRTAVYELLADADVQLK----VHAARFLLHHICVIPAEEFSTEYLRPQVHCIASYGQSANPSASCVSVTHETPPTALILDATSGGHFS-------------------PLPHEPSSPADVTNGVTLKAPQNQVTLRGLIPHLGRHVFVVHFYQAEHPGFPTEVVVDGGR-RWSGSFRASFCPHLLGCQDQVISEGQVEFDISEADVAVTVKIPDGKSLTLVRVLVVPAEDYDYHILHRTSVDKSSEFISSCGGDSFYIDPQAASGFCKNSARSLVAFYHNGAVPCECHPAGAAVHHCSPEGGQCPCRPNVIGRQCTRCATGYYGFPHCKPCNCG-RRLCEEVTGKCLCPPNTVRPQCEVCEMNSFNFHPVAGCEVCNCSRKGTVEAAVSECDRDSGQCRCKPRVTGQQCDKCAPGFYHFPECVPCSCNRDGTEPGVCDPGTGACMCKENVEGPQCQFCREGSFYLDSANPEGCTRCFCFGVNTDCRSSHKRRAKFVDMMGWRLETADGVDVPVSFNPSSNSVVADLQ----ELPSSVHSASWVAPPSYLG---------DKVSSYGGYLTYQAKSFGLPGDMVL-LEKQPDVQLIGQHMSIIHAEPSDPRPDRPHHGRVQVVEGNFRHAGNSAPVSREELMAVLSSLEGLHIRGLHFTETQRLTLGEVGLEEASDTGSGP---RAHLVEMCTCPPDYTGDSCQGCRPGYYRDIKSFPAGRCVPCNCNGHSNRCQDGSGVCINCQHNTAGEHCERCQEGYYGSA---IHGSCRVCPCP---HTNSFATGCAVD--GGAVRCACKPGYTGAQCERCAPGYFGNPQKFGGSCQPCNCNSNGQ----FGTCDPLTGDC------------------------------------------------------------------------------------------------------------------------------------------------------------VSQEPKDGSP---AEECDDCDSCVMTLLNDLVSMGEELRLVKSRLQGLSVSTGALEQIRHVEMQAKDLRNQLLGFRSAISSHGSKMDGLEKELSHLNQEFETLQEKAQVNSRKAQTLYNNIDQTIQNAKELDMKIKNIIQNVHILLKQIARPGGEGMDLPVGD-WSRELAEAQRMLRELRGRDFKKHLQEAEAQKMEAQLLLNRIRTWLESHQVENNGLLKNIRDSLNDYEAKLQDLRSVLQEAAAQGKQATGLNHENEGVLGAIQRQMKEMDSLKNDLTEHLATADASLLQTNSLLQRMDTSQKEYESLAAALNGARQELNDQVRELS-RSGGKAPLVAEAEKHAQSLQELAKQLEEIKRNTSGDELVRCAVDAATAYESILNAIRAAEDAAGKAASASESAFQTVIKEDLPRRAKTLSSDSEELLNEAKMTRKRLQQEINPALNSLQQTLKTVSVQKDLLDANVTAVRNDLRGIQRGDIDSVVSGAKSMVRKANGITSEVLDGLSPIQTDLGRIKDSYGSTR--HEDFNKALIDANNSVKKLTKKLPDLFVKIESINQQLLPLG----NISDNVDRIRELIQQARDAANKVAIPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR--PDLRENGGTEDMFVMYLGNK----DASKDYIGMAVVDGQLTCVYNLGDREAEVQIDQVLTESESQEAVMDRVKFQRIYQFAKLNYTKEATSNKPKAPAVYDLEGGSSNTLLNLDPEDAVFYVGGYP--PDFELPSRLRFPPYKGCIELDDLNENVLSLYNFKTTFNLNTTEVEPCRRRKEE-----SDKNYFEGTGYARIPTQPNAP--FPN-FIQTIQTTVDRGLLFFAENQDNFISLNIEDGNLMVRYKLNSEPPKEKGIR--DTINDGKDHSILITIGKLQKRMWINVN---ERSVRIEGEIFDFSTYYLGGIP----IAIRERFNISTPAFQGCMKNLKKTSGVVRLN--DTVG-VTKKCSEDWKLVRTASFSRGGQMSFTNLDVPSTDRFQLS-FGFQTFQPSGTLLNHQTRTSSLLVTLEDGHIELSTRDSNIPIFKSPGTYMDGLLHHVSVISDTSGLRLLIDDQVLR--RNQR------LPSFSNAQQSLRLGGG-------HFEGCISNVLVQRFSQ----------------SPEVLDLASKSTKKDASLGGCSLNKPPFLMLFKSPKRFNKGRIFNVNQLMQDAPQAT-RSTEAWQDGRSCLPPLNTKASHRALQFGDSPTSHLLFKLPQELLKP------------------------------------------RSQFSLDIQTT-SPKGLVFYTG---TKDSFLALYVADGRVVFALGA-GGKKLRLRSKERYHDGKWHTVVFGLNGGKARLVVDG-----LRAQEGSLPGNSTISPREQVYLGL------PLSRKPKSLPQHS-FVGCLRDFQLNSKPLDSPSARFGVSPCLGGSLEKGIYFSQGGGHVILANSVSLGPELKLTFSIRPRSLTGVLIHVGSQSGQ-RLSVYMEAGKVTTSVSSD-AGGSVTSITPKQSLCDGQWHSVAVSIKQRILHLELDTDSSYT-VAPLSFSPNSTRGSLHVGGVPDKLKMLTLPVWNSFFGCLKNIQVNHVPVPITEATEVQGSVSLNGCPDH--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61789-1", "uniprot_id": "LAMA3_MOUSE", "id": "Q61789-1", "name": "Laminin subunit alpha-3", "aln": "-----MAVALGRAPRSLPLLLT--LLLLLLLRMSPSWSVVGQDH-PMSSRSLHPPYFNLAQAARIWATATCGERDPE--VSRPRPELFCKLVGG-PAAQGS-GHTIQGQFCDYCNSEDSRKAHPASHAIDGSERWWQSPPLSSGTQYNQVNLTLDLGQLFHVAYILIKFANSPRPDLWILERSVDFGSTYSPWQYFAHSRRDCVEQFGQEANMAITQDDQMLCVTEYSRIVPLENGEIVVSLINGRPGAKKFAFSDTLREFTKATNIRLRFLRTNTLLGHLISKAERDPTVTRRYYYSIKDISVGGRCVCNGHAEACSADNPEKQFR---CECQHHTCGDTCNRCCAGYNQRRWQPAGQEQHNECEACNCHGHAVDCYYDPDVEHQQASLNSKGVYAGGGVCINCQHNTAGVNCEKCAKGYFRPHGVPVDALHGCIPCSCDPERAD-DCDQGSGHCHCKPNFSGDYCETCADGYYNFPFCLRIPVFPNYTPS-PEDPVAGNIKGCDCNLEG---------------------------------------------------------------------------------------------VLPEICD-DRGRCLCRPGVEGPQCDSCRS---------------------------------------------GSYSFPICQACQCSTIGSYPVPCDPGNGQCDCLPGITGRQCDRCLSGAYDFPYCQGSGSVCHPAG------TLDSSLG--YCQCKQHVASPTCSVCKPLYWNLAKENPRGCSECQCHEAGTLSGIGECGQEDGDCSCKAHVTGDACDTCEDGFFSLEKSNYFGCQGCQCDIGGALTTMCSGPSGVCQCREHVEGKQCQRPENNYYFPDLHHMKYEVEDGTGPNGRNLRFGFDPLVFPEFSWRGYAPMTSVQNEVRVRLSVRQSSLSLFRIVLRYISPGTEAISGRITLYS----SQGDSDALQSRKITFPPSKEPAFVTVPGNGFAGP--FSITPGTWIACIQVEG-VLLDYLVLLPRDYYEAFTLQVPVTEPCAHTGSPQ---DNCLLYQHLPLTAFSCTLACEARHFLLDGELRPLAMRQPTPTHPAMVDLSGREVELQLRLRVPQVGHYVVLLEYATEVEQLFVVDVNLKSSGSA-LAGQVNIYSCKYSIPCRSVVIDSLSRTAVHELLADADIQLK----AHMAHFLLYHICIIPAEEFSTEYLRPQVHCIASYRQHANPSASCVSLAHETPPTASILDATSRGLFS-------------------ALPHEPSSPAD---GVTLKAPQSQVTLKGLIPHLGRHVFVIHFYQAEHPGFPTEVIVNGGR-QWSGSFLASFCPHLLGCRDQVISDGQVEFDISEAEVAVTVKIPDGKSLTLVRVLVVPAENYDYQILHKTTVDKSSEFISSCGGDSFYIDPQAASGFCKNSARSLVAFYHNGAIPCECDPAGTAGHHCSPEGGQCPCRPNVIGRQCSRCATGYYGFPYCKPCNCG-RRLCEEVTGKCLCPPHTVRPQCEVCEMNSFNFHPVAGCDVCNCSRKGTIEAAVSECDRDSGQCRCKPRVTGQQCDKCAPGFYQFPECVPCSCNRDGTEPSVCDPETGACMCKENVEGPQCQLCREGSFYLDPTNPKGCTKCFCFGVNTDCQSSHKQRAKFVDMMGWRLETADGVDVPVSFNPGSNSMVADLQ----ELPPSVHSASWVAPPSYLG---------DKVSSYGGYLTYHAKSFGLPGDMVL-LGKQPDVQLTGQHMSLIHKEPSDPRPDRLHHGRVQVIEGNFRHEGSSAPVSREELMTVLSRLERLHIRGLHFTETQRLTLGEVGLEEASDTGSGP---RAHLVEMCACPPDYTGDSCQGCRPGYYWDNKSLPVGRCVPCNCNGHSNRCQDGSGICINCQHNTAGEHCERCQAGHYGNA---IHGSCRVCPCP---HTNSFATGCAVD--GGAVRCACKPGYTGTQCERCAPGYFGNPQKFGGSCQPCNCNSNGQ----LGPCDPLTGDC------------------------------------------------------------------------------------------------------------------------------------------------------------VNQEPKDGSP---AEECDDCDSCVMTLLNDLASMGEELRLVKSKLQGLSVSTGALEQIRHMETQAKDLRNQLLGFRSATSSHGSKMDDLEKELSHLNREFETLQEKAQVNSRKAQTLYNNIDQTIQSAKELDMKIKNIVQNVHILLKQMARPGGEGTDLPVGD-WSRELAEAQRMMRDLRSRDFKKHLQEAEAEKMEAQLLLHRIRTWLESHQVENNGLLKNIRDSLNDYEDKLQDLRSILQEAAAQAKQATGINHENEGVLGAIQRQMKEMDSLKNDFTKYLATADSSLLQTNNLLQQMDKSQKEYESLAAALNGARQELSDRVRELS-RSGGKAPLVVEAEKHAQSLQELAKQLEEIKRNTSGDELVRCAVDAATAYENILNAIRAAEDAASKATSASKSAFQTVIKEDLPKRAKTLSSDSEELLNEAKMTQKRLQQVS-PALNSLQQTLKTVSVQKDLLDANLTVARDDLHGIQRGDIDSVVIGAKSMVREANGITSEVLDGLNPIQTDLGRIKDSYESAR--REDFSKALVDANNSVKKLTRKLPDLFIKIESINQQLLPLG----NISDNVDRIRELIQQARDAANKVAIPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR--PDLRENGGTEDMFVMYLGNK----DASKDYIGMAVVDGQLTCVYNLGDREAEVQIDQVLTESESQEAVMDRVKFQRIYQFAKLNYTKEATSTKPKAPGVYDMESASSNTLLNLDPENAVFYVGGYP--PGFELPRRLRFPPYKGCIELDDLNENVLSLYNFKTTFNLNTTEVEPCRRRKEE-----SDKNYFEGTGYARIPTQPNAP--FPN-FMQTIQTTVDRGLLFFAENQDNFISLNIEDGNLMVKYKLNSEPPKEKGIR--DTINNGRDHMILISIGKSQKRMLINMN---KHSIIIEGEIFDFSTYYLGGIP----IAIRERFNISTPAFQGCMKNLKKTSGVVRLN--DTVG-VTKKCSEDWKLVRTASFSRGGQMSFTNLDVPSLDRFQLS-FGFQTFQPSGTLLNHQTRTSSLLVTLEDGHIALSTRDSSSPIFKSPGTYMDGLLHHVSVISDTSGLRLLIDDQVLR--RNQR------LASFSNAQQSLSMGGG-------YFEGCISNVFVQRMSQ----------------SPEVLDMASKSTKRDAFLGGCSLNKPPFLMLFKSPKGFNKARSFNVNQLLQDAPQAA-RSIEAWQDGKSCLPPLNTKATHRALQFGDSPTSHLLFKLPQELLKP------------------------------------------RLQFSLDIQTT-SSRGLVFHTG---TRDSFVALYLSEGHVIFALGA-GGKKLRLRSKERYHDGKWHSVVFGLSGRKVHLVVDG-----LRAQEGSLPGNSTISPREQVYLGL------SPSRKSKSLPQHS-FVGCLRNFQLDSKPLDSPSARSGVSPCLGGSLEKGIYFSQGGGHVVLANSVSLEPALTLTLSIRPRSLTGVLIHIASQSGE-HLSVYMEAGKVTTSMNSE-AGGTVTSITPKRSLCDGQWHSVTVSIKQHTLHLELDTDNSYT-AGQLSFPPNSTRGSLHIGGVPDKLKMLTLPVWNSFFGCLKNIQVNHIPVPITEATDVQGSVSLNGCPDH--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16787-2", "uniprot_id": "LAMA3_HUMAN", "id": "Q16787-2", "name": "Laminin subunit alpha-3", "aln": "-----MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPG--EGRPQPELYCKLVGG-PTAPGS-GHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFR---CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHAD-GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPS-SEDPVAGDIKGCDCNLEG---------------------------------------------------------------------------------------------VLPEICD-AHGRCLCRPGVEGPRCDTCRS---------------------------------------------GFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAG------TINSNLG--YCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEAVSGHITIYP----SWG---AAQSKEIIFLPSKEPAFVTVPGNGFADP--FSITPGIWVACIKAEG-VLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQ---ENCLLYQHLPVTRFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSV-LAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADIQLK----GHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALILDVLSGRPFP-------------------HLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGW-PRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCG-RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQ----ELPATIHSASWVAPTSYLG---------DKVSSYGGYLTYQAKSFGLPGDMVL-LEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGR---IALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA---VHGSCRACPCP---HTNSFATGCVVN--GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDC------------------------------------------------------------------------------------------------------------------------------------------------------------INQEPKDSSP---AEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD-FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELS-RSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQ--NEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLG----NISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR--PNSRENGGTENMFVMYLGNK----DASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYP--PDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE-----SDKNYFEGTGYARVPTQPHAP--IPT-FGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVG--DAINNGRDHSIQIKIGKLQKRMWINVD---VQNTIIDGEVFDFSTYYLGGIP----IAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVG-VTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQAS-FGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLR--NSKR------LKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSL----------------SPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLP--KTQANHGALQFGDIPTSHLLFKLPQELLKP------------------------------------------RSQFAVDMQTT-SSRGLVFHTG---TKNSFMALYLSKGRLVFALGT-DGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDG-----LRAREGSLPGNSTISIRAPVYLGS------PPSGKPKSLPTNS-FVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGK-HLCVYLEAGKVTASMDSG-AGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYT-AGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00174-1", "uniprot_id": "LAMA_DROME", "id": "Q00174-1", "name": "Laminin subunit alpha", "aln": "----------------------------MGHGVASIGALLVILAISYCQAELTPPYFNLATGRKIYATATCGQDTDG-------PELYCKLVGANTEHDHIDYSVIQGQVCDYCDPTVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEVNLTINFEQEFHVAYLFIRMGNSPRPGLWTLEKSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPITRDDDVICTTEYSKIVPLENGEIPVMLLNERPSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCDVKDPKSPVRILACRCQHHTCGIQCNECCPGFEQKKWRQNTNARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNTVGINCNKCKPKYYRPKGKHWNETDVCSPCQCDYFFSTGHCEEETGNCECRAAFQPPSCDSCAYGYYGYPNCRECECNLNGTNGYHCEAESGQQCPCKINFAGAYCKQCAEG----------------------YYGFPECKACECNKIGSITNDCNVTTGECKCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEICNKQSGQCICREGFGGPRCDQCLPGFYNYPDCKPCNCSSTGSSAITCDNTGKCNCLNNFAGKQCTLCTAGYYSYPDCLPCHCDSHGSQGVSCNS-DGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCN--CDPAGVIDKFAGCGSVPVGELCKCKERVTGRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDTCTSKSGQCPCKPHTQGRRCQECRDGTFDLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLACTQPLTTHFFPTLHQFQYEYEDGSLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNEVNVFK--SSLYRIVLRYVNPNAENVTATISVTS-----DNPLEVDQHVKVLLQPTSEPQFVTVAGPLGVKPSAIVLDPGRYVFTTKANKNVMLDYFVLLPAAYYEAGILTRHISNPCELGNMELCRHYKYASVEVFSPAATPFVIGENSKPTNPVETYTDPEHLQIVSHVGDIPVLSGSQNELHYIVDVPRSGRYIFVIDYISDRNFPDSYYINLKLKDNPDSETSVLLYPCLYSTICRTSVNEDGMEKSFYINKEDLQPVIISADIEDGSRFPIISVTAIPVDQWSIDYINPSPVCVIHDQQCATPKFRSVPDSKKIEFETDHEDRIATNKPP---------------------YASLDERVKLVHLDSQNEATIVIESKVDATKPNLFVILVKYYQPSHPKYQVYYTLTAGKNQYDGKFDIQHCPSSSGCRGVIRPAGEGSFEIDD-EFKFTITTDRSQSVWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHFHITHN-ASDFCKKSVFSLTADYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYYGFPDCKPCKCPNSAMCEPTTGECMCPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIANGNS-QCDLFNGTCECRQNIEGRACDVCSNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNVVGRDCDQCVDGTYNLQESNPDGCTTCFCFGKTSRCDSAYLRVYNVSLLKHVSITTPEFHEESIKFDMWPVPADEILLNETTLKADFTLREVNDERPAYFGVLDYLLNQNNHISAYGGDLAYTLHFTSG---FDGKYIVAPDVILFSEHNALVHTSYEQPSRNEPFTNRVNIVESNFQTISG-KPVSRADFMMVLRDLKVIFIRANYWEQTLVTHLSDVYLTLADEDADGTGEYQFLAVERCSCPPGYSGHSCEDCAPGYYRDPSGPYGGYCIPCECNGHSETCDCATGICSKCQHGTEGDHCERCVSGYYGNATNGTPGDCMICACPLPFDSNNFATSCEISESGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCKPCECSGNINPED-QGSCDTRTGECLRCLNNTFGAACNLCAPGFYGDAIKLKNCQSCDCDDLGTQTCDPFVGVCTCHENVIGDRCDRCKPDHYGFESGVGCRACDCGAASNSTQCDPHTGHCACKSGVTGRQCDRCAVDHWKYEKDGCTPCNCNQGYSRGFG--CNPNTGKCQCLPGVIGDRCDACPNRWVLIKDEGCQECNNCHHALLDVTDRMRYQIDSVLEDFNSVTLAFFTSQKLNYYDQLADELEPKVKLLD----PNSVDLSPSKKANSELESDAKSYAKQVNQTLANAFDIRERSSTTLGNITVAYDEAVKSADQAKEAIASVEALSKN-LEAAASTKIDAALEQAQHILGQING--TSIELTPNEQVLEKARKLYEEVNTLVLPIKAQNKSLN-ALKNDIGEFSDHLEDLFNWSEASQAKSADVERRNVANQKAFDNSK--FDTVSEQKLQAEKNIKDAGNFLINGDLTLNQINQKLDNLRDALNELNSFNKNVDEELPVREDQHKEADALTDQAEQKAAELAIKAQDLAAQYTDMTAS--AEPAIKAATAYSGIVEAVEAAQKLSQDAISAAG--NATDKTDGIEERAHLADTGSTDLLQRARQSLQKVQDDLEPRLNASAGKVQKISAVNNATEHQLKDINKLIDQLPAESQRDMWKNSNANASDALEILKNVLEILEPVSVQTPKELEKAHGINRDLDLTNKDVSQANKQLDDVEGSVSKLNELAEDIEEQQHRVGSQSRQLGQEIENLKAQVEAARQLANSIKVGVNFKPSTILELKTPEKTKLLATRTNLSTYFRT---------TEPSGFLLYLGNDNKTAQKNNDFVAVEIVNGYPILTIDLGNGP-----ERITSDKYVADGRWYQAVVDRMGPNAKLTIREELPNGDVVEHSKSGYLE-GSQNILHVD-KNSRLFVGGYPGISDFNAPPDLTTNSFSGDIEDLKIGDESVGLWNFVYGDDNDQGARERDVLLEKKKP---VTGLRFKGNGYVQLNATSNLKSRSSIQFSFKADKDTSNGLLFFYGRDKHYMSIEMIDGAIFFNISLGEGGGVQSGSQDRYNDNQWHKVQAERENRNGLLKVDDIVISRTNAPLEADLELPKLRRLYFGGHP-----RRLNTSISLQPNFDGCIDNVVINQGVVDLTEYVTGGGVEEGCSAKFSTVVSYAPHEYGFLRMNN---VSSDNNLHVVLHFKTTQPNGVLFYAANHDQSSTIGLSLQDGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDDVDNKRLGSPQPLILEGGDIFFAGLPDNYRTPRNALASLAYFVGCISDVTVNEEIINFANSAEKKNGNINGCPPHVLAYEPSLVPSYYPSGDNEVESPWSNADTLPPLKPDIESTLPPTTPTTTTTTTTTTTSTTTTSTTTTTTTPSPIVIDEEKEIEAKTPQKILTTRPPAKLNLPSDERCKLPEQPNFDVDFTEAGYRFYGLREQRLQINSLPVKVRRHHDIGISFRTERPNGLLIYAGSKQRDDFIAVYLLDGRVTYEIRVGAQLQAKITTEAELNDGTWHTVEVVRTQRKVSLLIDKLEQPGSVDLNAERSAPVLAVELPIYLGGVNKFLESEVKNLTDFKTEVPYFNGCLKNIKFDAMDLETPPEEFGVVPCS-EQVERGLFFNNQKAFVKIFDHFDVGTEMKISFDFRPRDPNGLLFSVHGKNSYAILELVDNTLYFTVKTDLKNIVSTNYKLPNNESFCDGKTRNVQAIKSKFVINIAVDFISSNPGVGNEGSVITRTNRPLFLGGHVAFQRAPGIKTKKSFKGCISKVEVNQRMINITPNMVVG-DIWQGYCPLN--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .* *.***** . :* *:****: :*:*****. . .*:** ** * . ..: ** :****:* ******** * ::*.**:*::: * *****::*::.*****.** **:* *:* *: ***.*: : ** ** : :*:** :*.****:********: * *:* **.: :: * *:::*:***:*:*:***:.*****:. * :********:*******:**:*:*:***:.*. .:* . .* * ***:*** *:.**.*::*: *: :*:.***:**: :* ** *.:: * . .. * ***** :***:*.*:**::* ::*. . : . * *.*: : *:: :*.* *:. * * ** *: .:* * :*: *. . * . .: *: *:* *: . **:** * . * :.:* * .* *.: ** .*.. *** * * . * :** * * *:** *: . *.*** . * *: :* . *. ** :*.* .*. ** *.* **:.. * *:* **.*. * * * ** * *: :. :**:.* **:**: *. :* *:*: . * * .* ::* **::: * * .: *.* :*:.:: * ** :**. : .:* : :.: .*: :::**:. . :.. ::: . * : : *:.** *:**. * : : ** : :.: *:***.**** **** * :::.* : :. . . . :: * . : * : ::: : :*: *:* .:::* : . : ::.* ** ** . : . :.. : . : . ::* : : :* :::* :::.* *: . .:. . . . . : . . ..:::: **. ** : . : .* * ..** **: : *: ::: . :. *: .: : * :::** . *. * . ..*:: :** *. : ::: . :* **:::. ** *:.** ** *. .*:. * * **** *: :** * * * : ::*** *:**.* :*: **:* ***..: * * :::. * : **: * *. * : ** .* *.*: .: *: ** *: *:. :* * *.*:. ** *** * * **:** * *: * *:: *: :* .*** ***** . * .: :. : : :.: . . * . .:*:* :::*:*** * * : . *** * .:: :: . . * .. . .:::::*.**: .*** ::* ** * : *:. . : * * * *. . * ** * **. * *.**: * **:* * .. * *:**:*:***: * .:* * ***.* * :**** *. .. . * *.** :*.** .* : .. :* *:.**:*. ** ** *::*:* :* *:**.*..* : . *.. ** * : *: *: * **: : : . :..:. : ::. : :*. :: . .:. :: * : . :. :* : . : . . :.:::: ::. * :: * .:. . :*:.* :: : :.. * ** : : :. * *: : . :. : : * * *: :: .: . *: : ..: . *. ** :* .* * :* . . . . *:.*:.**. *::*:.**:. : * : .: *: :.* * .: : *: :. : . :: :: . : : . ::: . .* .* . *. :. : : . : : :*. .:. : .:..* . :::: . :. .: .:: : ** *..: : :.*: : :.:: *.. * * *. .:: . *::*:*. : . *::.: : : . **. : . . .:* .::. . . . : :*:: .: ::***** . * * * : * ** :.:: :.*:** . : :.*.*:.:: : . * *::** . ..::.: : :* :.. .:. . . :: : : : *:** * . . **:..: * *. * * : *: . : : * : : . : *: * . * . : * * . ** * *:. : * :** . : * ****:* *:. . .*: . * . : .: : : . :: .. : . : : . :: . . :.::: .*:. : : :. . . * ** * . : *: * . * .. . * **:: :::. * :*. ** .* :* *::* . : : . . : :..** *::: : : : . . :. :***: : : . :.: :* .. . .. : *.:*. :: **: .: .* : :* : : ** ", "identical_positions": 678, "similar_positions": 879, "identity": "17.48%" }, { "cls_id": "homologset.agr.FB:FBgn0002542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A6T9-1", "uniprot_id": "A0A8I6A6T9_RAT", "id": "A0A8I6A6T9-1", "name": "Transcription termination factor 2", "aln": "---MEVIKCPEHGKVPVSGFPSWGLWNWLAGAIADLLVSSGAVCFLKTGVRDGPNKGKSFYVCRTNTCGFVQATDIP--------VSHCLLHEEFVVELQGLFLPQGKKEWRLFFRCARTKAEGKRWCGDVPWQ-DPNPKGHSVTCKPQLASESLPHPPSQPRNPFRVLNKNQKTLEWKQFVEGEGEIKTADKKL----------------RENREQLLDQKKEQKPKSKCRMEKDPSSDLVVTR-QSGGDGEEQEEKTKFRPKTKET-------EEMTSKQGHG-EVLQGTSKVPQIS-----------------ESESQEIPNKPEALSEKETHLLLQ--------------SIPGQNPESKVQKEGHLIRE--QLKNGDKTGADAHSAQASQTGLSQGSLQ-GPSKTWRPTP----------KARVAPGVCSGSVHHATSSSDDSEDDG------RPGSPLLFDLTIDSQKKGSLQHSDQSVQRQTAAASGVSKKGESSDLAAQRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALNALALSPEQGTRENCSSQEPEQSKVTETAAAGPLHLVPPQPLPRPHIQPAASLGLKASRQETPEGASQCSGGHTNEHRLYNV------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKITSEAIDELHRSLESCPGKTAVAEDPAGLKVPLLLHQKQALAWLLWRE----------------------------------------SQKPQGGILADDMGLG------KTLTMIALILTKKNQQKSKE--------------KDRSLPVMWLSKND-----------------------------SSVFTSTGTLIVCPASLIHHWKNEIEKRVNSNKLRIYLYHGPNRIQHAKVLSTYD----IVITTYSLLAKEIPTAKHEGEVPGAKLSVEGISAPLLQ----------------VVWARIILDEAHNVKNPRVQTSIAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDN-------------GSMKGGERLSILTKSLLLRRTKDQLDSTGKPLVPLPARSCQLHRLKLSEDERAVYDVFLARSRSALQSYLKR---------------------------------QEGRGSHPGRSPEN---PFSRVAQEFGSGVPQCSTAADSRRPS----TVHVLSQLLRLR-QCCCHLSLLKSVLDPKE--------LESEGLVLSLEEQLSALTLSKVDVSEPS-----------------------PTVSLNGTCFKVELFDDIRRSTKVSSLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLR----KNRLTYATIDGSVNPKQRMDLVEAFN-HSQGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQEKDVVMHRFVCEGTVEEKILQLQEKKKDLAK-QVLSGSGGPVTKLTLADLKILFGI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NC05-1", "uniprot_id": "TTF2_MOUSE", "id": "Q5NC05-1", "name": "Transcription termination factor 2", "aln": "---MDLVKCPEHG----------------------------DACFLKTGVRDGPNKGKSFYVCRTNTCGFVQATDIP--------VSHCLLHEEFVVELQGLFLPQDKKEWRLFFRCARTKAEGKQWCGNVPWRQDPNPKELSVTSKPQQPSESQLHSPSQPRNPFRVLNKNQKTLERKQFVE-EGERKTADKKL----------------RENNEQLLDQRKEQKPKSNSRMEKDPSSDLVATR-QSGGDREEQE-KSKFQPKTKKA-------EGMASKQGHG-EVLQGIPKGPHMS-----------------ESESRGVPNKPETLREKETQLLVP--------------SVPGQNPESKVQKEGHVSRE--PLKNGE-----APSAQVTQRGLAQGPLQ-GPSKTWRPVP----------EAPAAPELCSGMAHHATSSSEDSEDDGV---SSRPGSPLLFDSTVDSQKKGSLQHSDQSVQRQMPAASGVSKKGDSSDPAAQRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALSALALSPEQGTKEKCSAQEPEQSNITKAAAA-PLHLVPPQPLPRPLIQPASSLGLKAGRQETPEGASQCSGGHMNQHHLYNV------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKITSEAIDELHRSLKSCPGETAVAEDPAGLKVPLLLHQKQALAWLLWRE----------------------------------------SQKPQGGILADDMGLG------KTLTMIALILTKKNQQKSKE--------------KERSEPVTWLSKND-----------------------------SSVFTSSGTLIVCPASLIHHWKNEVEKRVTSNRLRIYLYHGPNRSRHAKVLSTYD----IVITTYSLLAKEIPTTKQEGEVPGANLSVEGTSAPLLQ----------------VVWARIILDEAHNVKNPRVQTSIAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDN-------------GSMKGGERLSILTKSLLLRRTKDQLDSTGKPLVALPARRCQLHRLKLSEDERAVYDIFLARSRSALQSYLKR---------------------------------QEGRGSHHGRSPDN---PFSRVAQEFGSSVSQGCPAADSQRPS----TVHVLSQLLRLR-QCCCHLSLLKSALDPTE--------LESEGLVLSLEEQLSALTLSKVDVSEPS-----------------------PTVSLNGTCFKAELFDDTRRSTKVSSLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLK----KNRLTYATIDGSVNPKQRMDLVEAFN-HSQGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQKKDVVIHRFVCEGTVEEKILQLQEKKKDLAK-QVLSGSEGPVTKLTLADLKILFGI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNY4-1", "uniprot_id": "TTF2_HUMAN", "id": "Q9UNY4-1", "name": "Transcription termination factor 2", "aln": "---MEEVRCPEHG----------------------------TFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIP--------VSHCLLHEDFVVELQGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQ-DPDSKEHSVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQ----------------REKGDQLFDQKKEQKPE---MMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS-----------------SGKSQDVQRESEPLREKVTQLLPQ--------------NVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPSIQATQKSLPQGHFQERPETHSVPAPG----GPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFTKTTTG-PPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAV------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRE----------------------------------------SQKPQGGILADDMGLG------KTLTMIALILTQKNQEKKEE--------------KEKSTALTWLSKDD-----------------------------SCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYD----IVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLR----------------IAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDN-------------GSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR---------------------------------HESRGNQSGRSPNN---PFSRVALEFGSEEPRHSEAADSPRSS----TVHILSQLLRLR-QCCCHLSLLKSALDPME--------LKGEGLVLSLEEQLSALTLSELRDSEPS-----------------------STVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLK----KHGLTYATIDGSVNPKQRMDLVEAFN-HSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAK-QVLSGSGESVTKLTLADLRVLFGI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34739-1", "uniprot_id": "TTF2_DROME", "id": "P34739-1", "name": "Transcription termination factor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------MSSENSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSSETAESEKSDESD----------------NSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRMSITGVR------PQDLSDDDSEIEYSDEVQEGPTEA-----------------PTAEAVVPRYTTQFAGNIQNDLHS--------------TIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRS--------------SAGASVVKTSKNLSQP-------------TIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHK-----------LPDKGSQIMKRIDTLRREL---------------AMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVN-EIKPVYTGAQGMATFNNQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------KALTLESLKDLHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWMSWRE----------------------------------------RKLPRGGILADDMGLG------KTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKG-----------------------------RKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKGKYLRDYD----IVVTTYQIVAREHKS-----------------LSAVFG----------------VKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDN-------------KSAGGQNRLNLLMKSLMLRRTKAQLQSDGK-LNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQ---------------------------------RAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLR-QICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDD----GPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLS----KDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKR-VLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLAD-GVLTG-AKVSSKLTIDDLKGLFGM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32849-1", "uniprot_id": "RAD5_YEAST", "id": "P32849-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase RAD5", "aln": "-------------------------------------------------------------------------------------------MSHIEQEERKRFFNDDLDTSETSLNFKSENKESFLFANSHNDDDDDVVVSVSDTTEGEGDRSIVPVRREIEEEGQNQFITELLRIIPEMPKDLVMELNEKFGSQ----------------EEGLSLALSHYFDHNSGTSISKIPSSPNQLNTLSDTSNSTLSPSSFHPKRRRIYGFRN-------QTRLEDKVTWKRFIGALQVTGMA-----------------TRPTVRPLKYGSQMKLKRSSEEIS--------------ATKVYDSRGRKKASMASLVRIFDIQYDREIGRVSEDIAQILYPLLSSHEISFEVTLIFCDN-----------KRLSIGDSFILQLDCFLTSLIFEERN------DGESLMKRRRTEGGNKREKDNGNFGRTLTETDEELESRSKRLALLKLFDKLRLKPILDEQK-ALEKHKIELNSDPEIIDLDNDEICSNQVTEVHNNLRDTQHEEETMNLNQLKTFYKAAQSSESLKSLPETEPSRDVFKLELRNYQKQGLTWMLRREQEFAKAASDGEASETG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------ANMINPLWKQFKWPNDMSWAAQNLQQDHVNVEDGIFFYANLHSGEFSLAKP-------------------------------------ILKTMIKGGILSDEMGLG------KTVAAYSLVLSCPHDSDVVDKKLFDIEN------TAVSDNLPSTWQDN-----------------------------KKPYASKTTLIVVPMSLLTQWSNEFTKANNSPDMYHEVYYGGNVSSLKTLLTKTKTPPTVVLTTYGIVQNEWTKHSKGRMTDEDVN----ISSGLFS----------------VNFYRIIIDEGHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQINYWKTFVSTPF--------ESKNYKQAFDVVNAILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSKSQDLLYKFLLDKAEVSVKSGIARGDL-----------LKKYSTILVHILRLRQVCCHPGLIGSQDENDEDLSKNNKLVTEQTVELDSLMRVVSERFDNSFSKEELDAMIQRLKVKYPDNKSFQSLECSICTTEPMDLDKALFTECGHSFCEKCLFEYIEFQNSKNLGLKCPNCRN-------QIDACRLLALVQTNSNSKNLEFKPYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEKELTHTFSKDVAKIYKFDGRLSLKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTCASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQEKKRTIGE-AMDTD-EDERRKRRIEEIQMLFE----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08562-1", "uniprot_id": "ULS1_YEAST", "id": "Q08562-1", "name": "ATP-dependent chromatin remodeler/ubiquitin-protein ligase E3 ULS1", "aln": "MAAVPTIDLTLADSDNEDIFHSFSSSTSVDKIDIRKENGKLRMAGLEVAQSNDDAARQAFHVFKTNISNNETFDTILSKSKTITDSTFNNEKSSNEVKQQQVLKEETMGSSNDEKKTQESSPSAEMIKLFYENDDVPLSDSFKQKEEGKRINQDEQVKENICGISSSYVSKDYDGVEDDFEPNTCQDSNLDFQEEKLNLNNKPSQQQFSDPETKDNSLKSENKDQIKGVTTTSYRDLPIESSAFQDSETQNNSKNTIPNIVNEKRTPALPSNLSSVESSLKNETAKVEGKTTVRLPGLQNNVALLEQEQSELFKHFSEQPVDISDFGRKIKRKHSGDFADNKILKRPILPSKNMDHTTHNSHDSEQKNSSIIILSDEDESGAGINDIESPLKVSEPNTADALRSSVPEVISLLDLPNIDLNNSVIKEASGSNSIPTSETDAQSSSSSVLQGTIMTEQATQSSQHECNSSLDTLKKNHQKLLKDLNSRESELRNALSCCKTNSEILRRKLSRREKEVSDAEKHWQLLLTSMARGGRTISSTQQILVDEAENQLNKLKEKRQLTKSKLDSINLKMYNYNEQWKSFVHSKNINLQKSLAALERSARDSKASATVNKRNECLAEKEKLDQMLKEGTLSFSTYKQLTGEIQQKLNDLKLGDQRTTDINSVLPIVRQPLAKRDLFIKSIDTAKDLLAKNTSRTEMTKRILYRHLDNLVSYKNFFEDGRSLIDINRRHVAHESAQILFTNGVKMPIVFETLQDYGIKFSNPAIVNPDRRAQYFKSIEVARDLISKSTRSEDAKRKITRFLNIIEEFRKDIDTGFPPTPLKREGVGKAVVGLRQQGLKMDRLYENLRRYKIPITSEELLQQSYLFPVNADQRPPSNWNIVENTEDTSSTANDLSMQDEFHISNMHAAEDQEQIRALLENVKQSESIIDGEALTPEDMTVNLLKHQRLGLHWLLQVENSAKKGGLLADDMGLGKTIQAIALMLANRSEESKCKTNLIVAPVSVLRVWKGELETKVKKRAKFTTFIFGGSGNGKVKHWRDLAR-YDAVLVSYQTLANEFKKHWPKKLDGEQNQLPAVPHIQALNRLKTSNEYYSPFFCNDSTFYRILLDEGQNIKNKNTRASKACCTINGMYRWVLSGTPIQNSMDELYSLIRFLRIPPYHKEQRFKLDIGRFFQRNKQYQYDNEDRKNALRKVRVLLNAIMLRRSKAD-KIDGKPLLELPPKIVEVDESRLKGEELKFYTALESKNQALAKKLLNNSTRGSYSSVLTLLLRLRQACCHSELVVMGEKKAEGTKVANGKSFEDDWLRLYYKITHMSGEAQAQVITSMNSMTCFWCMEQLEPEAMSVLTG---CGHLICDTCIEPFIEESSMLPQAKKTKGGAFAIPCKDCQRLTNEKDIVSHKLYDQVINQGFTEEDLHAEYLSEMEKQKIQQKNVYVPNFESLEPSTKIEQCIQVIQRVFDESATEKIIIFSQFTTFFEILEHFLKN---KLNFPYLKYIGSMNAQRRSDVINEFY-RDPEKR-ILLISMKAGNSGLTLTCANHVVIVDPFWNPYVEEQAQDRCYRISQTKKVQVHKLFIKDSVEDRISELQKRKKEMVDSAMDPGKIKEVNSLGRRELGFLFGLNAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . . . : . . : : . . . .. :. . . . . .: : : :. . : .. . . . : : : : : . . . : . . . ::: . : .: .. : : .. : *:: :. . : : : .. : . : . .*:: * *:: *..*. . . . .* . *:.:* : .* . : : **::**.: ::* :* * :.. :*.::**** * ::*:*::**. *: . :: :. . : : :.::***:* . *: * ** : : . :. .: .* . . . : . . : : . : . * : . . . : :. *:*: : :: .. :: ::.**::. :.:: * * . * : :.* .:: * :. : ::*:*: **. **.* ..* ::* *.* :* ** ** :*:.* :.* : ::. .::*::: :*.:* : . : .. . :: ** ", "identical_positions": 71, "similar_positions": 227, "identity": "4.36%" }, { "cls_id": "homologset.agr.FB:FBgn0002543", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCL0-1", "uniprot_id": "A0ABK0LCL0_RAT", "id": "A0ABK0LCL0-1", "name": "", "aln": "---------MTPLMFTLLLLFGFLCIRTD-------------------------------------------------GSRLR--QEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGTYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDEKEER--ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEDEPAEFRCQVQGDPQPTVRWKKDD--ADLPRGRYDIKDDYTLRIKKAISADEGTYVCIAENRVGKVEASATLTVR----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP-NQPQQPNSRCSVSPTGDLTITNIQRSDAG-YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDP-RATIQDQGTLQIKNLRIS-DTGTYTCVATSSSGETSWSAVLDV-TESGATIS--KNYDTNDLPGPPSKPQVTDVTKNSVTLSWQ-PGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVTVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTS----------------------GLQAS-TVWQNLDAKVP------------------------------------TERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTIRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIWCLGNETRFHIN-----KTVDATIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRNEVVIT--ENNNSI-TEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSN-YA---------------VTFQRGDGGLMSNGS-----RPGLLNTGDPS-YPWLADSWPATS-LPVNNSNSGPNEIGNFGRGDFKHNVNKNLAEHGIKKEFLGMERNKNDVLPPVPGQGDKTAT--MLSDGAIYSSIDFTTKT----TYNSSSQIT--------QATPYATTQILHSNSIHELAVDLP------------DPQWKS----SVQQKSDLMGFAYSLPDQNKGNNG------------------------------------GKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYPAEQENGYDSDSWCPPLPVQTYLHQGMEDELEEDED-----RVPTPPVRGVASSP-AISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYASGALISDLE----TDVPDEDADDEEEPLEIPRP-----------------LRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLT---------RTGKAFTSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQPVLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVESSTERKGSSLERQQAANLEDT--------------KSSLDCPAKTTVEWQHQTQDWINSTERQEETRKAPHKPGVGSEESLVPYSKPSFPSPG------GHSSSGTASSKGSTGPRKAEILRGSHQRNANDLLDIGYVGSNSQGQFTE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPD3-1", "uniprot_id": "ROBO2_MOUSE", "id": "Q7TPD3-1", "name": "Roundabout homolog 2", "aln": "---------MNPLMFTLLLLFGFLCIQID-------------------------------------------------GSRLR--QEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER--ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPRGRYDIKDDYTLRIKKAMSTDEGTYVCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP-NQPQQPNSRCSVSPTGDLTITNIQRSDAG-YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDP-RATIQDQGTLQIKNLRIS-DTGTYTCVATSSSGETSWSAVLDV-TESGATIS--KNYDMNDLPGPPSKPQVTDVSKNSVTLSWQ-PGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVVVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTS----------------------GLQAS-TVWQNLDAKVP------------------------------------TERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIWCLGNETRFHIN-----KTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRNEVVIT--ENNNSI-TEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSN-YA---------------VTFQRGDGGLMSNGS-----RPGLLNAGDPN-YPWLADSWPATS-LPVNNSNSGPNEIGNFGRG---------------------------DVLPPVPGQGDKTAT--MLSDGAIYSSIDFTTKT----TYNSSSQIT--------QATPYATTQILHSNSIHELAVDLP------------DPQWKS----SVQQKTDLMGFGYSLPDQNKGNNG------------------------------------GKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQENGYDSDSWCPPLPVQTYLHQGMEDELEEDED-----RVPTPPVRGVASSP-AISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPAPPLGYVSGALISDLE----TDVPDEDADDEEEPLEIPRP-----------------LRALDQTPGSSMDNLDSSVTG----------------------------------------------------------------------KAFSSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQPVLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVENSTERKGSSLERQQAANLEDT--------------KSSLDCPAKTVLEWQRQTQDWINSTERQEETRKAPHKQGVGSEESLVPYSKPSFPSPG------GHSSSGTSSSKGSTGPRKADVLRGSHQRNANDLLDIGYVGSNSQGQFTE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6N7-1", "uniprot_id": "ROBO1_HUMAN", "id": "Q9Y6N7-1", "name": "Roundabout homolog 1", "aln": "----MKWKHVPFLVMISLLSLSPNHLFLAQLIPDPEDVERGNDHGTPIP-----------------TSDNDDNSLGYTGSRLR--QEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDD--GELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ----EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFS-YQPPQSSSRFSVSQTGDLTITNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDS-RIKQLENGVLQIRYAKLG-DTGRYTCIASTPSGEATWSAYIEV-QEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSG----------------------ANHGE-SDWLVFEVRTP------------------------------------AKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKND-GNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHIN-----KTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSP--EDQVSL-AQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIR--KVPSFTFTPTVTYQRG-GEAVSSGG-----RPGLLNISEPAAQPWLADTWPNTG-NNHNDCSISCCTAGNGNSDSN-----------------LTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNN-MNNGSGDSG--------EKHWKP----LGQQKQEVAPVQYNIVEQNKLNKD-YRANDTVPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGAR-TPKVPKQGGMNWADL-LPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQ---DELEEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEED-NISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTRPAKKLKHQP--------GHLRRETYTDDLPPPPVPPP-AIKSPTAQSKTQLE-VRPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQNDGKGRGNKAAKRDLPPAKTHLIQED-ILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYERGEDNNEELEETES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O89026-1", "uniprot_id": "ROBO1_MOUSE", "id": "O89026-1", "name": "Roundabout homolog 1", "aln": "------------------MIAEPAHFYLFGLIC------------------------------------------LCSGSRLR--QEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDD--GELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ----EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFS-YQPPQSSSRFSVSQTGDLTITNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLILSCVATGSPAPTILWRKDGVLVSTQDS-RIKQLESGVLQIRYAKLG-DTGRYTCTASTPSGEATWSAYIEV-QEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQ-PNLNSGATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQSQYIQGYKILYRPSG----------------------ASHGE-SEWLVFEVRTP------------------------------------TKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKND-GNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNETKYHIN-----KTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSP--EDQVSL-AQQISDVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIR--KVPSFTFTPTVTYQRG-GEAVSSGG-----RPGLLNISEPATQPWLADTWPNTG-NNHNDCSINCCTAGNGNSDSN-----------------LTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQANLSNN-MNNGAGDSS--------EKHWKP----PGQQKPEVAPIQYNIMEQNKLNKD-YRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGAR-TPKAPKQGGMNWADL-LPPPPAHPPPHSNSEEYNMSVDESYDQEMPCPVPPAPMYLQQ---DELQEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEED-NISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAVVIQKARPAKKQKHQP--------GHLRREAYADDLPPPPVPPP-AIKSPTVQSKAQLE-VRPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVTDLRTNPSDPREAQEQPNDGKGRGTRQPKRDLPPAKTHLGQED-ILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T813-1", "uniprot_id": "A0AB32T813_DANRE", "id": "A0AB32T813-1", "name": "", "aln": "----MEFIPLVVSILAMLVMMGVQHGGTPGVPRHASLRNQPNQWCKRPHGSFLVGAHHRPTQQRHHNSKKHKCFQDFQRSRLR--QEDYAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRDDFRQNPVDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNIDDRDER--ITIRGGKLMITNTRKTDAGKYVCVGTNMMGERESEIAELTVLERPSFLRKPSSQSVLVDQSVEFRCEAQGDPVPTIRWRKED--GELPKGRYEIWEDHTLKLKRLTSGDAGTYTCQAENMMGKTEASATLTVH----VPPVFVVRPRNQVAGMGRTVTFQCEATGSPQPAIFWQKEGSQNLLFS-SQPPPPSSRFSVSQTGDLTITAVERSDGG-YYSCQALNIAGSVITKALLEVTDVISDRPPPIVRQGPTNQTVAVDGTVVLSCQATGTPIPTILWRKDGVLVSTHDS-RLKQLDTGALQIRYAKLG-DTGMYTCTASTPSGEASWKAYLEV-QEFGAPVQPGRPTDPNLIPSAPSKPDVTDVSRTSVSLSWK-PNLNAGATPTSYVIEAFSHAAGSSWQTLADHVKTESFVLKGLKPSAVYLFLVRAANAYGLSDPSPISDAVKTQDVPPTSQGVEHGQIQRELGDVVIHLHNPTILSSSSVRVQWTVEQQSQYIQGYKVMYRPSP----------------------EGAPQRVDWAMFEVGAP------------------------------------GEHSAVVTQLKKGITYEFKVRPFFNEFQGTDSDIKVGKTLEEAPSAAPRGVTVTGSG-DNGTAVLVAWQPPPEEEQNGVVQEYKIWCLGNESRYHIN-----RTVDGSTHSVLIPGLVAGVTYRLEVAAGTGAGPGVKSDPTSFQLDSSGRVLPPPLDDDNTI-SQQISDVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSSYAGIR--KVPSFTFTPTVAYQRG-GEAVSSAG-----RPGLLNIGEPATQPWLADTWPNSC-SNHNDCTINCCTGSNGNSDSN-----------------LATYSRPADCIANYSNQMDNKATNLLAPDTGLYSDVDLSNKINEMKTFNSPNLKDGRFMGPGGQPTPYATTQLIQSSLANNNMNSSSGGSGGGSADFNEKQSWKSSQGTPQKQADINTPLQYNVMEQNKLNKDHYRGEGPISVTIPYNQAQDVLTGETYSSSDRGSSTSGSQGQKKGGR-TTKQAKQNPMNWTEL-LPPPPVNPPP---CQEYTLVMDDSYDTDLQCPLPPSRMYLQP---DELEEEEDEVELERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEEMHPMLQDNPDLH-------ERRRLLVSPPPPPRPLSPPHTYGYISSPLGLDTDGLEEEDDDEEEGDETDAEVARVHQHHMMHPHQQHLPQQRALLRGLEQTPASSTCDLESSVTGSMINGWGSASEED-NASSGRSSAVSSSDGSFFTDADFAQAVAAAAEYAGLRVAKHPGKGHHQLPVSGAARKYQNLPAGHRPGSPVSTDSNVSAAPGQR-RPLKRQKQHPA----AQTGYQRREAYTEDLPPPPIPPPAMLKSPTHPAKTIPEGPRGAMSPRSSSADGKDRRTGAG------GPRVRDG---SDTRTSSSERRDGQDVQR-GQRTGKNSKQDEAVKSRQHPGSED-ILPYSRPSFPAVHSPRGERDPSSSSSLSSRGSGGRRRGEGPPGARRNPADIGLNTIGAFQTGGDELEMVES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z2I4-3", "uniprot_id": "ROBO3_MOUSE", "id": "Q9Z2I4-3", "name": "Roundabout homolog 3", "aln": "---------MLRYLLKTLLQMNLFADSLARDISNSSELLFGFNSSLAALN----------------PSLLPPGDPSLNGSRVG--PEDAMPRIVEQPPDLVVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGKIKLKEEEGR--ITIRGGKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLHWRKDD--GELPAGRYEIRSDHSLWIDQVSSEDEGTYTCVAENSVGRAEASGSLSVH----VPPQFVTKPQNQTVAPGANVSFQCETKGNPPPAIFWQKEGSQVLLFP-SQSLQPMGRLLVSPRGQLNITEVKIGDGG-YYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNIQWKKDERWLQGDDS-QFNLMDNGTLHIASIQEM-DMGFYSCVAKSSIGEATWNSWLRK-QED-WGASPGPATGPSNPPGPPSQPIVTEVTANSITLTWK-PNPQSGATATSYVIEAFSQAAGNTWRTVADGVQLETYTISGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRPAEDPWKGQRGLAEVAVRMQEPTVLGPRTLQVSWTVDGPVQLVQGFRVSWRIAG----------------------LDQGS---WTMLDLQSP------------------------------------HKQSTVLRGLPPGAQIQIKVQVQGQEGLGAESPFVTRSIPEEAPSGPPQGVAVALGG-DRNSSVTVSWEPPLPSQRNGVITEYQIWCLGNESRFHLN-----RSAAGWARSVTFSGLLPGQIYRALVAAATSAGVGVASAPVLVQLP-FPPAAEPGPEVSEGL-AERLAKVLRKPAFLAGSSAACGALLLGFCAALYRRQKQRKELSHYTAS--------FAYTPAVSFPHSEGLSGSSSR-----PPMGLG---PAAYPWLADSWPHPPRSPSAQEPRGSCCPSNPDPDDR---------------------YYNEAGISLYLAQTARGAN--ASGEGPVYSTIDP----------------------------VGEELQTFHGGFPQHSSGDPS--------------TWSQ-----------YAPPEWSEGDSG-----------------------------------------ARGGQGKLLG---KPVQMPSLSWPEALPPPPPSCELSCPEGPEE--ELKGSSDLEEWCPPVPEKSHLVG------SSSSG-----ACMVAPAPRDTPSP-TSSYGQQSTATLTPSPPDPPQPPTD----------------IPHLHQMPRRVPLGPSSPLSVSQPALSSHDG----------------------------------------RPVGLGAGPVLSYHASPSPVPS-------------------------------------------------------------------------TASSAPGRTRQVTGEMTP-PLHGHRARIRKKPKALP----------YRREHSPGDLPPPPLPPPEEETSWPLGLRAAGS---------MSSLERER----------------------------SGERRVVQAVPLGAQPLG-AQRGPHPDAALLGCAAEEAWLPYGRPSFLSHGQGTS--TCSTAGSNSSRGSNSSRGSRGSRGPGRSRSRSRSQSQSQRPGRNRREEPR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJI9-1", "uniprot_id": "A0A8I6AJI9_RAT", "id": "A0A8I6AJI9-1", "name": "Roundabout homolog 3", "aln": "---------MLRYLLKTLLQMNLFADSLAGDITNSSELLFGFNSSLAALN----------------PSLLPPGDPSLNGSRVG--PEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGNTKLKEEEGR--ITIRGGKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLRWRKDD--GELPTGRYEIRSDHSLWIEQVSAEDEGTYTCVAENSVGRAEASGSLSVH----VPPQFVTKPQNQTAAPGENVSFQCETKGNPPPAIFWQKEGSQVLLFP-SQSLQPMGRLLVSPRGQLNITEVKIGDGG-YYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNVQWKKDETWLQGDNS-QFNLMDNGTLYIASVQEM-DMGFYSCVAKSSIGEATWNSWLRK-REH-WGASPGPATEPGNPPGPPSQPIVTEVTTNSITLTWK-PNPQSGARATSYVIEAFSQAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRPVEDPWKGQQGLAEVAVRMQEPIVLGPRTLQVSWTVEGPGQLVQGFRVSWRIAG----------------------LDQGS---WTALDVQSP------------------------------------HKQSTVLRGLPPGSQIQIKVQVQGQEGLGAESPSVTRSIPEEAPSGPPQGVAVALGG-DRNSSITVSWEPPLPSQQNGVITEYQIWCLGNESRFHLN-----RSAAGWARSVMFRGLLPGLLYRAIVAAATSAGVGVASAPVLVQLP-FPPVAEPGPEVSEGL-AERLSRVLRKPAFLAGSSAACGALLLGLCAALYRRQKQRKELSHYTAS--------FAYTPAVSFPHSEGLSGSSSR-----PPMGLG---PAAYPWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDR---------------------YYNEAGISLYLAQTARGAN--APGEGPVYSTIDP----------------------------VGEELQTFHGGFPQHSSGDPS--------------TWSQ-----------YAPPEWSEGDSG-----------------------------------------ARGGKGKLLG---KPVQMPSLSWPEALPPPPPSCELSCPEGPEE--ELKGSSDLEEWCPPMPEKKHLID------SRSSG-----ACMVAPARGETPSP-TSSYGQQSTATLTPSPPDPPQPPSD----------------IPHLHQMPRRVPLGPSSPLSVSQPALSSHDG----------------------------------------RPVGLGAGPIVSYHPSPSPVPS-------------------------------------------------------------------------TASSAPGRTRQVTGEMTP-PLHGHRARIRKKTKALP----------HRREHSPGDLPPPPLPPPEEETSWPLGLRAAGS---------MSSLEREH----------------------------SGERRVAQAVPLGAQPPG-AQRGPHPDAALLGCAAEEAWLPYGRPSFLSHGQGTS--TCSTAGSNSSRGSNSSRGSRGSRGPGRSRSR--SQSQSQRPGRNRRQEPR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PC46-1", "uniprot_id": "M9PC46_DROME", "id": "M9PC46-1", "name": "", "aln": "MHLCEMRGMPLRLQPQCLTNESEIQIKIKSKIKNKTASEIKRRHRNNRDFHGERLKIMPVDRSRRAVFPLLLLLAGLNGLTQVGALKGENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTG---SHRIMLPAGGLFFLKVIHSRR-ESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGNMPLRRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVH----APPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVD-TQFELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITVGTRYFNSGLDLSEARASLLSGDVVELSNASVVDSTSMKLTWQIIN-GKYVEGFYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTSASASASASALISTKPNIAAAGKRDGETNQSGGGAPTPLNTKYRMLTILNGGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSEAPYGMEALLLN---SSAVFLKWKAPELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAASPTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLDPFINQRYPINQDHVNDVLTQPWFIILLGAILAVLMLSFGAMVFVKRKHMMMKQSALNTMRGNHTSDVLKMPSLSARNGNGYWLDSSTGGMVWRPSPGGDSLEMQKDHIADYAPVCG-APGSPAGGGTSSGGSGGAGSG--------------------------ASGGDDIHGGHGSERNQQRYVGEYSNIPT----------------------------DYAEVSSFGKAPSEYGRHGNAS----------------------------PAPYATSSILSP-----------------------------------------HQQQQQQQPR-----YQQRPVPGYGLQRPMHPHYQQQQHQQQQAQQTHQQHQALQQHQQLPPSNIYQQMSTTSEIYPTNT---------GPSRSVYSEQYYYPKDKQRHIHITENKLSNCHTYEAAPGAKQ-------SSPISSQFASVRRQQLPPNCSIGRESARFKVLNTD-----------------------------------------QGKNQQNLLDLDGSSMCYNG------------------------------------------------------------------------LADSGCGGSPSPMAMLMSHEDEHALYHTADGDLDDMER-----------LYVKVDEQQPPQQQQQLIPLVPQHPAEGHLQ-----------SWRNQSTRS------------------------SRKNGQECIKEPSELIYAPGSVASERSLLSNSGSGTSSQPAGHNVXPLLPGS------SLGQSQSKSQSQSQSQSDLQSQEQLYAREVRELLAWCERFNNGGVENFE---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ***:*:* * *.:.:* *: *:***.* *.::*:*.* .: * :**::**:*.*** :::*.*: ..* * * * *:* :* * *:**:*:**.***:** .* :. ** ** *::** .*:* *** : *:*. :. : : **:* : : ::* * * ** .*: * *:* * * * ** ::: * . . .. * *. *** * : *:: .::* * .: .* :* : * * *.* *:* :* *:. *:*: ** ** :*::* . * * * *::.* * *:::* **.. **:. : . . *.*: . * * *:::. .**: ::: :.: . : **:: *** ***: : . * * . * * * : * : . : : . : *.* * : * * *:* *.. *:::*.. : . . *..*.:* :.: .:::*:* .. . .*:** *.: . * : . *: . ** *.. *:*::** .. *:* ** :*:.: . *. .:.: :. :: . ::.: * : : ::*: : * : * * .: * :: :. * * *:.** .* .: . . .::: : *..* . ::*:: :*:: * :: .::. : . :: : * * * ***...** * . * . : . : : ::: *: :* *: .. ::: : :: ::*: :: .. * ... * . :** * . .. . . : . *. : . : . . . . . : : : * * . . : * : . * .. . .:* :* . . :. * . . . : . . . . .: . . : ** * . .. : .: . . : : *. * . . ", "identical_positions": 224, "similar_positions": 337, "identity": "12.14%" }, { "cls_id": "homologset.agr.FB:FBgn0002552", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJ11-1", "uniprot_id": "A0ABK0LJ11_RAT", "id": "A0ABK0LJ11-1", "name": "", "aln": "MRYIVEIKMESVQEILDHLYRKVLLGATLEDDLHGYIVYLNPDLSEQAVCTASSVARSDVRDVLDGMAGQHG-----VSILPEAQECSRRQLQTGRAWEVTLLQLTLIDMVLSRVLSAETESRAKAGYRELTEVLLQSIELDSKLIRVLQNSDKLLSYLAAKCLASLLYFQLREK-----KMLSNSWVTFCQKHLSDSSEGGEAVHCLCVLAAVMKEIFKDAHSQRAESLKQLLTPFDNTFEAFYNS-----LFSQHFGNFKNPSNIISSLMCFLELLELLVASRIHLKLHLRSQRMLFLKP-HALDILAWPIPAFIKRKLVILIKKCLLCKVGEDFCRESVPTLMSPDHLLDSDMLALADALLHAIHLG---------------LWKALTVPGKPSCFGGDEVQPGCRLRAGPDHVTLRAASLITVKSLEIKFQNCTSATEMKADLQKF-LPEFLAFLKPQLQPSLQLHNPCEWLSRVFIEQDDDMLEAAKASLSIYLHLTREWDTSTSLTP--------------EKEAWIHSTHGHGYNPHCIFLFFLKNIAFDSTVLLDFLISSETCFLEY----FVKYLKLLQKDWGHFLSTCQFFAAMESQCGVSVHDPFPLPAHGTSTSYTAPHAP----VGENACPWIPWAADASSEPQSQ---PKETHPVPTNGPPSRTPQSLVDYDSSEPSDEEATDEPLANSKQTS------------LCQEMPGEIQDLPRTCKGKE-RSREPQARPLLSAEPNSPFSDDGGVAP--------------------------------------------------FLRTVRCLEELQRAIYRLQEKNLFPYNPAALLKLLKGVEAKCDNV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1D0-1", "uniprot_id": "LINES_MOUSE", "id": "Q3U1D0-1", "name": "Protein Lines homolog 1", "aln": "MRYILDIKMEIVQEILDQLYRKVLLGTTLEDDVHGYIFYLNPDLSEQDGCPAFPVAQSNASGVLDGMAGQHGPSSHEVATLPGAQECPKRQLQMDRTREMKLLQLTVIDTMLSQVLSDETETHAKEGYRELTEVLLQSVELDSKLMRMLQNSDKLLSHMAAKCLASLLYFQLREKVRSQHKMLSNSWVTFCQKHLSESSESGEAVRCLWILTAVIKEILKDTHSQRAESLKQLLTPFDITFEVFYNS-----LFSQHFGDFQSPSNLASSLMCFLELLELLVASRIHLKLHFRSQRMLFLKP-HALDILAWPIPAFIKRKLVILVKKCLLCKVGEDLCREPAPSLMSPDHLLDSDMLTLADTLLHAVHVG---------------LWKALAVSGKPSCFGGDEVQPGCRLRTGPDHVTLRAASLITVKSLEIKSQNCTSAAEMKVALQTF-MSELLAFLKPHLQPSLQPHNPCEWLSRVFIEQDDDMLEAAKASLSIYLQLTREWDASASLTQ--------------EKEAWIRSTHGHGCNPHCVFLFFLKNVAFDSTVLLDFLISSETCFLEY----FVKYLKLLQKDWAHFLSICKFFAAVESQCGMLVHDPVPSPARGRSTSLTVPHAPAS-PVGENTCPWLPWASDASSESQSQVMMPKETLPVPANGPPSRTPQSLVDYDSSEASEEETTSEHLANSKQTS------------LCQERSEEIQGLPRTWEEQ----KEHSLEPLLSAESSSPFSAKGRVAADGTVW-----------------------------------------QVGLFLRTVKCLEELQGAIYRLQEKNLFPYNPAALLKLLKGVEAKCVNV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG48-1", "uniprot_id": "LINES_HUMAN", "id": "Q8NG48-1", "name": "Protein Lines homolog 1", "aln": "--------MKVFCEVLEELYKKVLLGATLENDSHDYIFYLNPAVSDQDCSTATSLEWANTC----GIQGRHQPISVGVAPIAVAPVCLKTNSQMSGSREVMLLQLTVIKVMTTRILSVKTEFHAKEQYRDVIKILLESAKVDSKLICMFQNSDKLLSHMAAQCLALLLYFQLREK-----ITLSNSWIAFCQKNLSEYSESNKAIYCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNS-----LFSQHFENCRDTSKIVNILMCFLDLLELLIASRIHLKLHFTCQRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHHVAVDMLALANAVLQAVNSG---------------LLKTLSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEVKVDLQRF-MSELLTFLKPHLQPSLQLHNPCKWLSRVFIEQDDDMLEAAKASLGIYLTLTRGCEATESLTQ--------------GKEMWDHHTHENGYNPHCIFLFFLKNIGFDSTVLLDFLISSETCFLEY----FVRYLKLLQKDWDNFFTICNNFDATESKYDISICGCVPSLVQDQSSNQTIPHRLTAPHSHRDVCARHSWASDAPSEPLKAVMSKGAHTMCASSLSSPRASQSLVDYDSSDDSDVESTEQCLANSKQTS------------LHQQATKEIQDAAGTSRDKKEFSLEPPSRPLVLKEFDTAFSFDCEVAPNDVVS-----------------------------------------EVGIFYRIVKCFQELQDAICRLQKKNLFPYNPTALLKLLKYIEVISNKTMNTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4Z9-1", "uniprot_id": "LINES_DROME", "id": "Q9V4Z9-1", "name": "Protein lines", "aln": "-MDTSSAAGSGAGTGDVCPCSTVATSTTSASNEQPQTKRQKIEQQIKVGSKALPPQPPHPPDILDLDANSNSHLCSSLSSSSSHSLSTPSTANNSPTTTPCSSRAASYAQLLHNILPQNGDTDLHSQPESAHDEVDRAAKLPNLLTLDTTNGNGSHASSRSNCLQATTATSIDDM-----LEFEQSLTRQCLCGVSERTLR-KPFQSHYSQDTNGQKRIAYLREWPTNKLLQFLSNLQLLFDIYLKQNAKGFICTRIMDVCDALIRNDHKLIDEIIVLAGYENSYVQFLAGRVLAAFLVIAKQELNDEWLQKIVDQLFNFEQLDQAAVQKIHFSLDIIKRIVEWKDMEIHPLDDDWMASANSTSAASSVVPLSTEASVSYMHFPVQEQPLATNYFALQFREDTEGERETGQEAPDNRDRHRRHFGEDMNVAYEPHPAPQSTTMPSGCHVVTLTDSESFDTTHLKCITIQKLEHKWPTLVKNMSELMAPTHQDAAEHCVLNFLQLWENIISVKANLSIDETRPYYAQLDKFELLLSHSLSCTVYKQMLCLFNEALCYGSTLALQDMLPEETCKLAHQIVCHVRGFRILESLPRRQPDNMVSLIGYNGKPMVYANGTITLAHAAQSGDSEEDGAPLDLIEMDKTLLQKMVLLVLKSIAVTVKEIRSDSSDSSIDSTDYDAFQDMMLIERSIRDVLSKLETFIKQTLEFHPECHFSKILIHLFDDQDDHLIEAMVCTLDVTSGISFRNNAFPELVAMLNPVYTFLEFLKMTSNSSDLLLDLLVSNETCFLLYLLRLLKYIRMNWTMFVHSCHTFGMGSAMLDEAMGVLIRLRLQISRLVSRQLYPYDISPVLRLLESCESLYEGNELS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* .:* .: : : . : . * . .. . : :: . . : . : : : : .:*. : : : .. . : .: :: . * *.: : ::** .: : :.:* * :*: : :.. . : :: : . :: * *:*: :: *: : :. : :: : . *: : :* * ::: :*.: : * : . : :.. *: : . * : * :: *:: * :.*:. * * .**: : : .: : : ..:: : : . :.: :* ..:*: : :* : * .: .*: * : : : *:. * : :: :* : : :.**: *: ::..*** * : .*: :::*:. . : . :.: : . .. * . .. * . . . . . : *.:: : * . . . : :: : : :: *: * . * : .. :: : : . : : .*: * ** .::*:**: :.:*:**: * ", "identical_positions": 66, "similar_positions": 221, "identity": "7.62%" }, { "cls_id": "homologset.agr.FB:FBgn0002561", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19359-1", "uniprot_id": "ASCL1_RAT", "id": "P19359-1", "name": "Achaete-scute homolog 1", "aln": "MESSGKMESG-----AGQQPQPP--QPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQAPQQQAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAAN----------KKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSP-----------------------TISPNYSNDLNSMAGSPVSSYS----SDEGSYD-PLSPEEQELLDFTNWF-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02067-1", "uniprot_id": "ASCL1_MOUSE", "id": "Q02067-1", "name": "Achaete-scute homolog 1", "aln": "MESSGKMESG-----AGQQPQPP--QPFLPPAACFFAT-AAAAAAAAAAAAQSAQQQQPQ-APPQQAPQLSPVADSQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAAN----------KKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSP-----------------------TISPNYSNDLNSMAGSPVSSYS----SDEGSYD-PLSPEEQELLDFTNWF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50553-1", "uniprot_id": "ASCL1_HUMAN", "id": "P50553-1", "name": "Achaete-scute homolog 1", "aln": "MESSAKMESGG----AGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAAN----------KKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSP-----------------------TISPNYSNDLNSMAGSPVSSYS----SDEGSYD-PLSPEEQELLDFTNWF-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90259-1", "uniprot_id": "ASL1A_DANRE", "id": "Q90259-1", "name": "Achaete-scute homolog 1a", "aln": "MDITAKMEIS-----VNQQ-------QFMPP-ACFFAS---------------------------QSIQLSP-TDSQCS---NKSASKQAKRQRSSSPELLRCKRRLNFAGFGYSLPQQQPHAVARRNERERNRVKLVNNGFATLREHVPNGAAN----------KKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSP-----------------------TISQNYSNDMNSMAGSPVSSYS----SDEGSYD-PLSPEEQELLDFTNWF-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90260-1", "uniprot_id": "ASL1B_DANRE", "id": "Q90260-1", "name": "Achaete-scute homolog 1b", "aln": "MEATVVATTQ-----------------------------------------------------LTQDSFYQPFSESLEK---QDRECKVLKRQRSSSPELLRCKRRLTFNGLGYTIPQQQPMAVARRNERERNRVKQVNMGFQTLRQHVPNGAAN----------KKMSKVETLRSAVEYIRALQQLLDEHDAVSAVLQCGVPSP-----------------------SVSNAYS----AGPESPHSAYS----SDEGSYE-HLSSEEQELLDFTTWFDRYESGASMATKDWC----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35885-1", "uniprot_id": "ASCL2_MOUSE", "id": "O35885-1", "name": "Achaete-scute homolog 2", "aln": "MEAHLDWYGVPGL-QEASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDGGALPRLMPTSSGVAGACAARRRQASPELLRCSRRR---RSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGGAN----------KKLSKVETLRSAVEYIRALQRLLAEHDAVRAALAGGLLTPATPPSDECAQPSASPASASLSCASTSPSPDRLGCSEPTSPRSAYS----SEESSCEGELSPMEQELLDFSSWLGGY----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09774-1", "uniprot_id": "AST3_DROME", "id": "P09774-1", "name": "Achaete-scute complex protein T3", "aln": "MTSICSSKFQQ------------------------------------QHYQLTNSNIFLLQHQHHHQTQQHQLIAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLP---SVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYN-DSLDSSQQFLTGATQSAQSHSYHSASPTPSYSGSEISGGGYIKQELQEQDLKFDSFDSFSDEQPDDEELLDYISSWQEQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1LUI6-1", "uniprot_id": "F1LUI6_RAT", "id": "F1LUI6-1", "name": "", "aln": "MNSNFCRALVDR---------------------------------GSPGGIQLG---VVAPAGPTPLAATEPLGN---VPFLLYPGHSEPSYYDAYTGVFPYVPFPGAFGVY---DYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAE----------KRLSKVETLRAAIRYIKYLQELLSAAPDGAP---PTAT---------------------------SPPPAHAGHGNALQPPSLVAESS-GSSFSPSPFLESEEPSL--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QWB7-1", "uniprot_id": "ASCL5_MOUSE", "id": "M0QWB7-1", "name": "Achaete-scute homolog 5", "aln": "MNSNFCRALVDR---------------------------------GPPGGMQLG---VVAPAGQTPLAATEPLSN---VPFLLYPGHSEPPYYDAYTGVFPYVPFPGAFGVY---DYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALTE----------KRLSKVETLRAAIRYIKYLQELLSATPDGAP---PPAT---------------------------SPPPAHTGHSNVPQPSSLVAESS-GSPFSSSPFLESEEPSL--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU5-1", "uniprot_id": "ASCL5_HUMAN", "id": "Q7RTU5-1", "name": "Achaete-scute homolog 5", "aln": "MNNNFCRALVDRR------------------------------PLGPPSCMQLG---VMPPPRQAPLPPAEPLGN---VPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFGVY---EYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAE----------KRLSKVETLRAAIRYIKYLQELLSSAPDGST---PPASRGLPGTG-------------PCPAPPATPRPDRPGDGEARAPSSLVPESSESSCFSPSPFLESEESWH--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJR7-1", "uniprot_id": "ASCL3_MOUSE", "id": "Q9JJR7-1", "name": "Achaete-scute homolog 3", "aln": "MDTRSYPSPPDRLS-----------------------------VFAESAHLPLSRPFYLDPMVTVHLCPETPVPASYTDELPLLPFSSDTLIMNNYGDPYP-FPFPMPYTNYRRCDYTYGPAFIRKRNERERQRVKCVNEGYARLRRHLPEDYLE----------KRLSKVETLRAAIKYISYLQSLLY--PDESE---TKKN----------------------------PRTASCG---SLDPALRVI-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M7F4-1", "uniprot_id": "A0ABK0M7F4_RAT", "id": "A0ABK0M7F4-1", "name": "", "aln": "MEKCKSAGLLALH--------------------------------SPLRASPLG-----A------LARREPCRVS-----ARQDTA-------DCARRRPCPSLPP--------GGVAEPAFLRQRNERERQRVRCVNEGYARLRQHLPRELAG----------QRLSKVETLRAAIGYIKQLQELLER-----------------------------------------HRPDLNSDGESKASSGASPCSS-----------EPEERG---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QW46-1", "uniprot_id": "M0QW46_MOUSE", "id": "M0QW46-1", "name": "", "aln": "MEKRRSAGLLALP--------------------------------SALRTAPLG-----A------LPGREPCRVS-----VRQDAA-------DCARRRPYSSLPL--------GGVAEPAFLRQRNERERQRVRCVNEGYARLRQHLPRELAG----------QRLSKVETLRAAISYIKQLQELLER-----------------------------------------HRPDCNSDGESKASSGASPCS------------ESEERS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XD76-1", "uniprot_id": "ASCL4_HUMAN", "id": "Q6XD76-1", "name": "Achaete-scute homolog 4", "aln": "METRKPAERLALP--------------------------------YSLRTAPLG-----VPGTLPGLPRRDPLRVA-----LRLDAACWEWARSGCARGWQYLPVPL--------DSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELAD----------KRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAG---------------------------AVPQRRAECNSDGESKASSAPSPSS------------EPEEGGS--------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :** ***:**: ** *: ** *:* :::***:*** *: ** ** :* . ", "identical_positions": 27, "similar_positions": 13, "identity": "9.09%" }, { "cls_id": "homologset.agr.FB:FBgn0002566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQ35-1", "uniprot_id": "A0A8I6AQ35_RAT", "id": "A0A8I6AQ35-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDESGEHMGVCSEDGKLQVFGLYSGEEFHET-FDCPIKIVAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKIFDITSKQRITNVPRDD-----ISLRPDMYPCSLCWKDAVTLIIGWGTSIKICSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISHRNIKRHKILEIGLAYVNHLVERGEYDMAARKCQKILGKNA---------------SLWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSLNAPAQYCNICSAKNRGPGSAILEMKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5KU39-1", "uniprot_id": "VPS41_MOUSE", "id": "Q5KU39-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDDSGEHMGVCSEDGKLQVFGLYSGEEFHET-FDCPIKIIAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKVFDITSKQRISNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSIKICSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQRNIKRHKILDIGLAYVNHLVERGEYDMAARKCQKILGKNA---------------SLWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSMNAPAQYCNICSAKNRGPGSAILEMKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49754-1", "uniprot_id": "VPS41_HUMAN", "id": "P49754-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFDVSP-----VKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET-FDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHE--------------GEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERH-------------------------------ASEMR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSE----------------TCEEISSDALTVRGFQENECRDYHLEYSEGESL--FYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNA---------------ALWEYEVYKFKEIGQLKAISPYLPRGDP-VLKPLIYEMILHEFLESDYEG-FATLIREWPGDLYNNSVIVQAVR----------DHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSE-------------------KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFK-RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRN-FVEETVYLLSRMG--NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F590-1", "uniprot_id": "VPS41_DANRE", "id": "E7F590-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAEVEEQGRKLSEESTDESEEEDTEEEPKLKYERLTNGVTEILQKDAASCMTVHDKFLALGTHFGKVFLLDIQGN-VTQKFEISS-----VKINQISLDESGDHVGICSEDGKVQVFGLYTREGFHEN-FDCPIKVVALHPQFSKSNNKQFVTGGNKLLLYERNWLNRWKTSVLHE--------------GEGNITSVKWRGNLIAWANNVGVKIYDIGSKQRITNVLRDN-----TSLRPDMYPCSLCWKDNTTLIIGWGCSVKICAVKERD-------------------------------PTEMR--DLPSRYVEIVSAFETEFFISGLAPL-ADQLVTLYYVKENSDHMEEEFRTRPRLDIIQPLPE----------------GCEEISSDALTVRNFQENQCRDYRLEHSEGESL--FYIISPKDIVVAKERDQDDHIDWLLEKKKYEEALMAAEISFKNIKRHDVQKIGMAYINHLVEKGDYDTAARKCQKVLGKNM---------------DLWENEVYRFKTIGQLKAISQYLPRGDL-RLRPAIYEMILHDFLKTDYEG-FATLIREWPGELYNNMAIVQAVN----------EHLKKDPTNSILLTTLAELYTYDQRYDRALEIYLRLRHKDVYQLIHKHNLFSSIKDKIVLLMDFDKE-------------------KAVDMLLDNEDKISMDKVVEELKDRP-----ELLHVYLHKLFK-RDHHKGQKYHERQISLYAEFDRPNLLPFLRESMHCPLEKALEICQQRH-FVEETVFLLSRMG--NCRRALQMIMEELANVDKAIEFAKEQDDRELWEDLISYSIDKPPFITGLLNNIGTHVDPILLIHR-IKEGMEIPNLRDSLVKILHDYNLQILLREGCKKILVADSLSLLQRMHRTQKKGVRVDEENICESCHTPILPSDTAQAFGVVVFHCRHMFHKECLPSPGSIPGIQYCNICSAKRRGPGSGILEMKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PL76-1", "uniprot_id": "VPS41_DROME", "id": "Q7PL76-1", "name": "Vacuolar protein sorting-associated protein 41 homolog", "aln": "-----------------------------------------------------------------------MAKALP--LISCDSWADSINEE--DVEPKFKYHRLANDLKYMLNADVITCSAVHLKFLIFGTFRGRVCIFDHQGNSVYSNLSASERHTHQVAVNNIDVDHKGEYVATCSDDGKVNITGLFSSDNNHSLSFGKFIKVVSLEPDS-KAHIKRFVVGDDKLILYERNLLKKLKPVELCS--------------VEGSVLSICWHGNFIAWASHIGVRVYDLNERCSLGLIKWEVP----PQERLENFRCHLRWSNKHTLLIGWVDTIRVCVIRKRN-------------------------------SIEASTGNLPVYIVDPISTFQTTFYVCGLAPLSAKQLVVLGFRKEKSSCFK---ALRPVLCVIEYKMN----------------NSEEICTDSLTLRGFEEYTVNDYSLGGIIEENR--FYIVAPKDIVVASLIETDDRIEWLIKHSKFEEAMELISANGGNVP---VLSVAKLYINHLLALKKYDDAAKLCLRMLGNDK---------------VLWEEEVFKFVKCQQLRSVSAYLPTSDECKLDPHVYEMVLYEFLKFDVCG-FLNLIKEWPSHLYDGLAVINAIH----------DNFRKHYAN-QLLESLALLYSYQGDFESALRMYLKLQNKDVFQLIRRYELYDVISKLIIPLIQLDRD-------------------CAFEILLDKK-KIKTEIVVHQLEHNQ-----EYLYWYLDSLLK-KDPSN--VFQKKLISLYAIFDRNKLLPFLKRSKDYDIQEALVICKQEN-FYPEIVYLLGCMGGVEASEALNIIIHRIRDIEMAIEFCKEHDDSDLWNALINEFSKHPEIVTKVLDGIVDYFSPAVVVGK-IKMGQNIPNLRQSLIKMLRHYNLQGEILSSAQQIQLNDYFEIHSEIVTTQRRGQQVSYEQLCSLCHRPVLMAG-THLYCIIRLECGHVYHKPCIQG----ELLKNCNECNLWKLTVGK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38959-1", "uniprot_id": "VPS41_YEAST", "id": "P38959-1", "name": "Vacuolar protein sorting-associated protein 41", "aln": "MTTDNHQNDSVLDQQSGERTIDESNSISDENNVDNKREDVNVTSPTKSVSCISQAENGVASRTDESTITGSATDAETGDDDDDDDDDDDEDEDDEDEPPLLKYTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHLTTCAFEPIKTIKCHRS--------SILCINTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNFQASRMFVSGGMAGDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILWMDDDGITFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLFKVSFTKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVSMLITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDLFNGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFDWFMERKQYYKAWKIGKYVIGSEER---FSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLNSLDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKKPA--LRKSVYDDVLHYFLANDMINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYLKENKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIFEIQTIFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMISPYENQLIELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIG--ETKKALSLIIDELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYLKVIRGMSDDLQIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQGKLFQVDESDIEINDDLNGVL----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :. *. :*: : * :** *::: . ::: * :. . .*: :**. * : : : : . : :: .*.:.. * **.: : .: : . * *: :::... : .::* :*. : . * . :* : .: *.:* * .. *: . *: : : : . * : : : : : ::*** .: : : . . . * *: . * . : : ***.: .**: * : : .. : . : : :** .* : ::.::: .** * :. :*:::..* : .. . .*:::*::::.:: :* . . .:. ::* *: .:. . :: : * : : :: :: :* * :*: :*: ** * . * * :* .*:. . : :. ::. * *. ** : : *: * :. . :*: :* . *: :: : . ..::*:::. .*. : . ::. : . ** .::. * :.:: *.**: :** .*****: . ::.*: :*... : * ::* . :* : **.:*:..: : : **:* *: .* :**: :* .:* : . :* . : : : :. . :* **:: : ::::. .*. : .. * : .: ..: : :* .. :: : ", "identical_positions": 112, "similar_positions": 292, "identity": "10.58%" }, { "cls_id": "homologset.agr.FB:FBgn0002567", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8QZZ8-1", "uniprot_id": "RAB38_MOUSE", "id": "Q8QZZ8-1", "name": "Ras-related protein Rab-38", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDLLES-IEPDIVKP----HLTSPKVVS-CSGCAKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63483-1", "uniprot_id": "Q63483_RAT", "id": "Q63483-1", "name": "Ras-related protein Rab", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLVNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDFIES-IEPDIVKP----HLTSPKVVS-CSGCAKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57729-1", "uniprot_id": "RAB38_HUMAN", "id": "P57729-1", "name": "Ras-related protein Rab-38", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQAPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVSVVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDLMES-IEPDVVKP----HLTSTKVAS-CSGCAKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T7H0-1", "uniprot_id": "A0A8N7T7H0_DANRE", "id": "A0A8N7T7H0-1", "name": "Ras-related protein Rab", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQ---KEHLFKVLVIGDLGVGKTSIIKRYVHQIFSQHYRATIGVDFALKVLHWDSQTVVRLQLWDIAGQERYGNMTRVYYREAVGALIVFDVTRSSTFDAVLKWKDDLDLKVSLNNGKPVPAVLLANKSDQSREGLCSQIPKLDTFCKENGFVGWFETSAKENSNIEAAAKCLVDHILAHEENIVNN-TDPDVVALPGYNNNTKERVRSRCMTCSKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q13637-1", "uniprot_id": "RAB32_HUMAN", "id": "Q13637-1", "name": "Ras-related protein Rab-32", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSP-SQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFPNEENDVDKIKL----DQETLRAENKSQCC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZE3-1", "uniprot_id": "RAB32_MOUSE", "id": "Q9CZE3-1", "name": "Ras-related protein Rab-32", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGEGLGQQ--GASATAAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQKKDNSQSP-SQMDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQQSFPSEEIDLDRIKL----VEEPPTTKPRSQCC---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1Z7S3-1", "uniprot_id": "A1Z7S3_DROME", "id": "A1Z7S3-1", "name": "", "aln": "MPNVDEQRGKAATKRAESEQSEEKGDRQEGDGDPKDESEEATAKIKGRSRFTAALRSLSKTKTKRERELDKSTDRETRSAEEEAQETPGELEDVASSISTDSGALGKTKKKSLTRRLLLGGLRKSGKTPKGRPHSLATSDDISVEHLETTPLPSPPGSPTSAGSSTLQITISGKKVEPSPAKKSGKSRPKSDTDYLTPAAEERKPRKKTTTTTVTTRDTSSSTRTTKLLVSKKKPQSPERESPSASPSPLITTTESTRDTPPRERAPAKPSRVQSASGTGAVRKSQSSSASSRKLELMQQQQQRGHRLNARPLAELANTEPQPSGQQSLDPSTSPPAAEDGVSSAESAQTIANPPPVVRFEVGSAVRSPLSAYEAALAAAASQQPNSNEELSDSSIRRLSFAQQQLILGDHDSIEGRRETLHYQSVASEYSNQDSGSEDDSEEQADTTEPENAKPMPAFGDLTMDQEMEPAIMTSTSDKREHLYKILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKVLQWDANTIVRLQLWDIAGQERFGNMTRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLPDGSPIPCILLANKCDQEKQGIITQPEKMDEYVRENGFAGWFETSAKENINIDEAARALVNKILINDKLISADLADGDKFNLS-AADATGSDAKNKCSC----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:*:****:**.****:******* **.:**************:**..*:*************:********:**:**::***::*..**:.* ***.*** *: * :*.*:. :*****.** :: . ::* : :::**.********:* **: *:: **.::* :. : . : * . . . ", "identical_positions": 108, "similar_positions": 56, "identity": "15.63%" }, { "cls_id": "homologset.agr.FB:FBgn0002569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CW41-1", "uniprot_id": "MALX4_YEAST", "id": "P0CW41-1", "name": "Oligo-1,6-glucosidase IMA4", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFN-FSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNG---TDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDE-SKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLD--------NKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CW40-1", "uniprot_id": "MALX2_YEAST", "id": "P0CW40-1", "name": "Oligo-1,6-glucosidase IMA3", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFN-FSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNG---TDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDE-SKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLD--------NKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08295-1", "uniprot_id": "IMA2_YEAST", "id": "Q08295-1", "name": "Oligo-1,6-glucosidase IMA2", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFN-FSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNG---TDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDE-SKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLD--------NKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38158-1", "uniprot_id": "MAL32_YEAST", "id": "P38158-1", "name": "Alpha-glucosidase MAL32", "aln": "-------------------------------------------------------------------------------------------------------MTIS-DHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDN--ALYTSAARYEVSEVFS-FTHVELGTSPFFRYNIVPFTLKQWKEAIASNFLFING---TDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQE-SRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLD--------SDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVSSRVLKPWEGRIYLVK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53341-1", "uniprot_id": "MAL12_YEAST", "id": "P53341-1", "name": "Alpha-glucosidase MAL12", "aln": "-------------------------------------------------------------------------------------------------------MTIS-DHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDN--ALYTSAARYEVSEVFS-FTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFING---TDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQE-SRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLD--------SDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVSSRVLKPWEGRIYLVK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40884-1", "uniprot_id": "IMA5_YEAST", "id": "P40884-1", "name": "Oligo-1,6-glucosidase IMA5", "aln": "-------------------------------------------------------------------------------------------------------MTII-----HNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEGLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYMLSQVPEGKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFN-FKHTSVGENPKCKYELIPFTLKDFKLALAESFLFIEN---TDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQIKCVEGTGTYAAIKRDYGEDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFS-KDAKPWIDMNESFRDGINAEAE-LKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLD--------NDKLFMFTKDTDNKKMFAVFNFSSDNTDFSVPDNEASYTMFFGNY--ANSNGDSRTLQPWEGRLYLLK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q91WV7-1", "uniprot_id": "SLC31_MOUSE", "id": "Q91WV7-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MDEDKGKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPG-SRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSR-TRSGKYTDYYIWHN--CTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIT-FWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTS---QIPDTVTHYSELYHDFTTTQVG-MHDIVRDFRQTMNQYSREPGRYRFMGAEASAESIERTMMYYGLPFIQEADFPFNKYFTTIGTLSGHTVYEVITSWMENMP--EGKWPNWMTGGPETPRLTSRVGSEYVN-------AMHMLLFTLPGTPITYYGEEIGMGDISVTNFNESYDSTTLVSKSPMQWDNSSNAG-FTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLS-RGWFCL-LRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASKGSAVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64319-1", "uniprot_id": "SLC31_RAT", "id": "Q64319-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MNEDKDKRDSIQMSMKGCRTNNGFVQNEDIQEQDPD---SRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSR-TRSGKYTDYYIWHN--CTHANGVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIK-FWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTS---QIPDTVTRYSELYHDFTTTQVG-MHDLVRDFRQTMNQFSREPGRYRFMGTEVSAESTERTMVYYGLSFIQEADFPFNKYLATLDTLSGHTVYEAITSWMENMP--EGKWPNWMIGGPETSRLTSRVGSEYVN-------AMNMLLFTLPGTPITYYGEEIGMGDISITNLNERYDTNALLSKSPMQWDNSSNAG-FTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHARELLLS-RGWFCL-LRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASKGSDVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07837-1", "uniprot_id": "SLC31_HUMAN", "id": "Q07837-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MAEDKSKRDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALSPKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSR-TRTGKYTDYYIWHD--CTHENGKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKEILR-FWLTKGVDGFSLDAVKFLLEAKHLRDEIQVNKT---QIPDTVTQYSELYHDFTTTQVG-MHDIVRSFRQTMDQYSTEPGRYRFMGTEAYAESIDRTVMYYGLPFIQEADFPFNNYLSMLDTVSGNSVYEVITSWMENMP--EGKWPNWMIGGPDSSRLTSRLGNQYVN-------VMNMLLFTLPGTPITYYGEEIGMGNIVAANLNESYDINTLRSKSPMQWDNSSNAG-FSEASNTWLPTNSDYHTVNVDVQKTQPRSALKLYQDLSLLHANELLLN-RGWFCH-LRNDSHYVVYTRELDGIDRIFIVVLNFGES-TLLNLHNMISGLPAKMRIRLSTNSADKGSKVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07191-1", "uniprot_id": "MAL2_DROME", "id": "P07191-1", "name": "Maltase A2", "aln": "------------------------------------------------------------------------------------------MPKWAHLGLAALLLISTTQEGTADIDWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNFYDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVNREDG-YDDFYVWDDGKLNEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLDVLK-FWLDRGVDGFRIDAVPHIYEHRNADGSYPDEPVSGWGSDPNAYDYHD---HIYTKDQPATVDLMYEWREFLDNYRAQNGGDSRVLLAEAYSSVETLSAYFGNSTHQGTQLPMNFQLMYLSGYSTAKDVVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGAHKVD-------LLNVIVNALPGASVTYYGEEIGMSNVDVECTGDSCEDRDG-ERTPMQWTAGKNAD-FSDGESTWLPLSPEYQRYNVQTERGVSRSSLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIRTNKISEEYRILVNMGNGMEILDGL--------APKTYEYVLATAYSTHYSGQKADLSQRIILMPYEAVVLRWLA---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**: ..:***** **:**: ** **: ** .:* *:. :. : *: .:: *. .*: * : :: .: * :** :* :: :. *:*.* *:: ** * :: **: * . . *::.* . * **.** * :... * ::* : ::: * * *:*: * :. : : :** :.**** :*. : . : . . : . :: : . : : . * . . : .. . : * *.. . . : : :*.*: * *:*:* :. . :: ..:: :. . :: . . :.: . : . . . . . . . : * . .:: : . . .. : . ", "identical_positions": 69, "similar_positions": 140, "identity": "9.77%" }, { "cls_id": "homologset.agr.FB:FBgn0002570", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CW41-1", "uniprot_id": "MALX4_YEAST", "id": "P0CW41-1", "name": "Oligo-1,6-glucosidase IMA4", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDP-FTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFN----FSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEK----------YEDVEVRNNYDAIKEEHGENSKE-MKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLD--------NKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CW40-1", "uniprot_id": "MALX2_YEAST", "id": "P0CW40-1", "name": "Oligo-1,6-glucosidase IMA3", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDP-FTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFN----FSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEK----------YEDVEVRNNYDAIKEEHGENSKE-MKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLD--------NKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08295-1", "uniprot_id": "IMA2_YEAST", "id": "Q08295-1", "name": "Oligo-1,6-glucosidase IMA2", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDP-FTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFN----FSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEK----------YEDVEVRNNYDAIKEEHGENSKE-MKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLD--------NKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38158-1", "uniprot_id": "MAL32_YEAST", "id": "P38158-1", "name": "Alpha-glucosidase MAL32", "aln": "-------------------------------------------------------------------------------------------------------MTIS-DHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNW-GSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDN--ALYTSAARYEVSEVFS----FTHVELGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEK----------YEDVDVKNNYEIIKKSFGKNSKE-MKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLD--------SDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVSSRVLKPWEGRIYLVK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53341-1", "uniprot_id": "MAL12_YEAST", "id": "P53341-1", "name": "Alpha-glucosidase MAL12", "aln": "-------------------------------------------------------------------------------------------------------MTIS-DHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNW-GSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDN--ALYTSAARYEVSEVFS----FTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEK----------YEDVDVKNNYEIIKKSFGKNSKE-MKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLD--------SDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVSSRVLKPWEGRIYLVK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40884-1", "uniprot_id": "IMA5_YEAST", "id": "P40884-1", "name": "Oligo-1,6-glucosidase IMA5", "aln": "-------------------------------------------------------------------------------------------------------MTII-----HNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEGLPDAPITDPTVPYQKGTE-FFINGPRIHEYHKEMHNYMLSQVPEGKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFN----FKHTSVGENPKCKYELIPFTLKDFKLALAESFLFIENTDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQ----------IKCVEGTGTYAAIKRDYGEDSEK-MKKFFEALALISRDHGRTPFPWSADEPSAGFS-KDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLD--------NDKLFMFTKDTDNKKMFAVFNFSSDNTDFSVPDNEASYTMFFGNY--ANSNGDSRTLQPWEGRLYLLK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q91WV7-1", "uniprot_id": "SLC31_MOUSE", "id": "Q91WV7-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MDEDKGKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPG-SRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSRT-RSGKYTDYYIWHN--CTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIT-FWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTVTH-----YSELYHDFTTTQVGMHDIVRDFRQTMNQYSREPGRYRFMGAEASAESIERTMMYYGLPFIQEADFPFN-KYFTTIGTLSGH-TVYEVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVN-------AMHMLLFTLPGTPITYYGEEIGMGDISVTNFN------------ESYDSTTLVSKSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLS-RGWFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASKGSAVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64319-1", "uniprot_id": "SLC31_RAT", "id": "Q64319-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MNEDKDKRDSIQMSMKGCRTNNGFVQNEDIQEQDPD---SRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSRT-RSGKYTDYYIWHN--CTHANGVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIK-FWLSKGVDGFSFDAVKFLLEAKDLRNEIQVNTSQIPDTVTR-----YSELYHDFTTTQVGMHDLVRDFRQTMNQFSREPGRYRFMGTEVSAESTERTMVYYGLSFIQEADFPFN-KYLATLDTLSGH-TVYEAITSWMENMPEGKWPNWMIGGPETSRLTSRVGSEYVN-------AMNMLLFTLPGTPITYYGEEIGMGDISITNLN------------ERYDTNALLSKSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHARELLLS-RGWFCLLRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASKGSDVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07837-1", "uniprot_id": "SLC31_HUMAN", "id": "Q07837-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MAEDKSKRDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALSPKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSRT-RTGKYTDYYIWHD--CTHENGKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKEILR-FWLTKGVDGFSLDAVKFLLEAKHLRDEIQVNKTQIPDTVTQ-----YSELYHDFTTTQVGMHDIVRSFRQTMDQYSTEPGRYRFMGTEAYAESIDRTVMYYGLPFIQEADFPFN-NYLSMLDTVSGN-SVYEVITSWMENMPEGKWPNWMIGGPDSSRLTSRLGNQYVN-------VMNMLLFTLPGTPITYYGEEIGMGNIVAANLN------------ESYDINTLRSKSPMQWDNSSNAGFSEASNTWLPTNSDYHTVNVDVQKTQPRSALKLYQDLSLLHANELLLN-RGWFCHLRNDSHYVVYTRELDGIDRIFIVVLNFGES-TLLNLHNMISGLPAKMRIRLSTNSADKGSKVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07190-1", "uniprot_id": "MAL1_DROME", "id": "P07190-1", "name": "Maltase A1", "aln": "-------------------------------------------------------------------------------------------MRPQSAACLLLAIVGFVGAT----EWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVD-SDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVIR-FWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDNKRVASRFGVQRTD-------LINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPNACNSDPDNYYARSRDPARSPYQWDASSKAGFTSADHTWLPVADDYKTNNALQQLRAPRSHLQIFKKLVRVRK-EPSFR-QGELNIQAIDDDVIIYSRQKTGSD-LYVIVLNLGSTSKTLDLTKYYELG----------------------------TQAEVITTSLSSQYIDGDVIKSTEFVANPYVGTVLVAV-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**: . ***** **:**: ** **: *: .**:*:. :. *: .::.*. *: * : :: :: * :** :* :: :. *:*.* *:: ** * :: ** * *:::*: . * **.** * : *:* ::* : ::: * * *:*:.* . : : :** :.*.** :*. : : : . . . * . :: : . : : . . : : . :.. . : * :*.. : . : * :*.* * *:*:* :. : : . . .*: :. . *: * : : . . * . . . : :. . : * ::* : : . . . : ", "identical_positions": 75, "similar_positions": 128, "identity": "10.46%" }, { "cls_id": "homologset.agr.FB:FBgn0002571", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CW41-1", "uniprot_id": "MALX4_YEAST", "id": "P0CW41-1", "name": "Oligo-1,6-glucosidase IMA4", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKD----WKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNN------------YDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CW40-1", "uniprot_id": "MALX2_YEAST", "id": "P0CW40-1", "name": "Oligo-1,6-glucosidase IMA3", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKD----WKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNN------------YDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08295-1", "uniprot_id": "IMA2_YEAST", "id": "Q08295-1", "name": "Oligo-1,6-glucosidase IMA2", "aln": "-------------------------------------------------------------------------------------------------------MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKD----WKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNN------------YDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38158-1", "uniprot_id": "MAL32_YEAST", "id": "P38158-1", "name": "Alpha-glucosidase MAL32", "aln": "-------------------------------------------------------------------------------------------------------MTIS-DHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDN--ALYTSAARYEVSEVFSFTHVELGTSPFFRYNIVPFTLKQ----WKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNN------------YEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVSSRVLKPWEGRIYLVK---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53341-1", "uniprot_id": "MAL12_YEAST", "id": "P53341-1", "name": "Alpha-glucosidase MAL12", "aln": "-------------------------------------------------------------------------------------------------------MTIS-DHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDN--ALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQ----WKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNN------------YEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVSSRVLKPWEGRIYLVK---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40884-1", "uniprot_id": "IMA5_YEAST", "id": "P40884-1", "name": "Oligo-1,6-glucosidase IMA5", "aln": "-------------------------------------------------------------------------------------------------------MTII-----HNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEGLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYMLSQVPEGKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFNFKHTSVGENPKCKYELIPFTLKD----FKLALAESFLFIENTDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQIKCVEGTGT------------YAAIKRDYGEDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFS-KDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLDNDKLFMFTKDTDNKKMFAVFNFSSDNTDFSVPDNEASYTMFFGNY--ANSNGDSRTLQPWEGRLYLLK---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q91WV7-1", "uniprot_id": "SLC31_MOUSE", "id": "Q91WV7-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MDEDKGKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPG-SRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSR-TRSGKYTDYYIWHN--CTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIT-FWLSKGVDGFSFDAVKFLLEAKDLRNEIQVN---TSQIPDTVTHYSELYHDFTTTQ-VGMHDIVRDFRQTMNQYSREPGRYRFMGAEASAESIERTMMYYGLPFIQEADFPFNKYFTTIGTLS--GHTVYEVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVN-------AMHMLLFTLPGTPITYYGEEIGMGDISVTNFNESYDSTTLVS-------------KSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLS-RGWFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASKGSAVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64319-1", "uniprot_id": "SLC31_RAT", "id": "Q64319-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MNEDKDKRDSIQMSMKGCRTNNGFVQNEDIQEQDPD---SRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIISPKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSR-TRSGKYTDYYIWHN--CTHANGVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKEIIK-FWLSKGVDGFSFDAVKFLLEAKDLRNEIQVN---TSQIPDTVTRYSELYHDFTTTQ-VGMHDLVRDFRQTMNQFSREPGRYRFMGTEVSAESTERTMVYYGLSFIQEADFPFNKYLATLDTLS--GHTVYEAITSWMENMPEGKWPNWMIGGPETSRLTSRVGSEYVN-------AMNMLLFTLPGTPITYYGEEIGMGDISITNLNERYDTNALLS-------------KSPMQWDNSSNAGFTEANHTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHARELLLS-RGWFCLLRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASKGSDVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07837-1", "uniprot_id": "SLC31_HUMAN", "id": "Q07837-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MAEDKSKRDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALSPKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSR-TRTGKYTDYYIWHD--CTHENGKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKEILR-FWLTKGVDGFSLDAVKFLLEAKHLRDEIQVN---KTQIPDTVTQYSELYHDFTTTQ-VGMHDIVRSFRQTMDQYSTEPGRYRFMGTEAYAESIDRTVMYYGLPFIQEADFPFNNYLSMLDTVS--GNSVYEVITSWMENMPEGKWPNWMIGGPDSSRLTSRLGNQYVN-------VMNMLLFTLPGTPITYYGEEIGMGNIVAANLNESYDINTLRS-------------KSPMQWDNSSNAGFSEASNTWLPTNSDYHTVNVDVQKTQPRSALKLYQDLSLLHANELLLN-RGWFCHLRNDSHYVVYTRELDGIDRIFIVVLNFGES-TLLNLHNMISGLPAKMRIRLSTNSADKGSKVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07192-1", "uniprot_id": "MAL3_DROME", "id": "P07192-1", "name": "Maltase A3", "aln": "----------------------------------------------------------------------------------------------MFKLLVLSCLLALALPSLAEVGWWKTGQFYQIYPRSFKDSDGDGVGDLIGITQQLPYLKEIGITATWLSPIFTSPMADFGYDVADLKGIDPIFGTMEDFEALLARAKELDIKIILDFVPNHTSDECDWFIRSA-AGEEEYKDFYVWHT--GKVVNGIRQPPTNWVSVFRGSMWTWNEQRQAYYLHQFHAKQPDLNYRNPKVVEAMKDVLR-FWLRKGAYGFRIDAVPHVYEIPADADGNWPDE-PRNEAVSDPEDYTYLQHIYTTDQ-PETLELVYAFRDVIEEIDAELGGDDRVLLTEAYSPLEVLMQYYGNGTHLGSQIPFNFELLAKISYSSDAYHYSELIHNWLDNMPEGQVANWVFGNHDQSRIGSRLGADRID-------ACNMIILGLPGVSVTYQGEEMGMTDVWIS-WEDTVDPQACQSNEQEFERLTRDPVRTPFQWSDEVNAGFSNASVTWLPVASNYKLVNVKKERGIALSHLNVYKQLRALRD-EPTLK-QGDVSVTAIGPNVLAFKRSLAGYK-SYITLININDDVESINLDSVFTSITTQLQYVVVNDKS------------VRRKNDLTFANSVLLLPKEAVVLSTV--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: . .***** *****: ** **: ** .:* *:. :. : *: .:: *. *: * : : . : * :** :* :: :. .:*.* *:: ** * : ** * : *::.*: :* **.** * : .* * ::* ::: * * *:*:.* . : : :** :.. ** :*. : : : : * : . * :: : . . : : . . : . : . .. . : .* :*.. : . : *.*. * *:*:* :. :. . . .. . :. :: . . . : : . : * . . . : : . : . . ::*. .: . . : . . ", "identical_positions": 70, "similar_positions": 133, "identity": "9.76%" }, { "cls_id": "homologset.agr.FB:FBgn0002576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63046-1", "uniprot_id": "RUNX1_RAT", "id": "Q63046-1", "name": "Runt-related transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------MRIP-----------------------------------------VDASTS-------------------------RRFTPPSTALSPGKMSEALPLGAPDG-GAALAS---------------------------------------------KLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLD----------DQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDARQIQPSPP-WSYDQSYQYLGSITSS-VHPATPISPGRASGMTSLSAELSSRLSTAPDLTAFGDP-----RQFPTLPSISD-----PRMHYP-GAFTYSP-PVTSGIGIGMS---------------------------AMSS-TSRYHTYLPPPYP-GSSQAQA-GPFQTG-------------------SPSYHLYYGTSAGSYQFSMVG------GERSPP--------------------------------RILPPCTNASTGAALLNPSLPSQSD-VVETEGSHSNSPTNMPP-----------------------------------------ARLEEAVWRPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03347-1", "uniprot_id": "RUNX1_MOUSE", "id": "Q03347-1", "name": "Runt-related transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------MRIP-----------------------------------------VDASTS-------------------------RRFTPPSTALSPGKMSEALPLGAPDG-GPALAS---------------------------------------------KLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLD----------DQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDARQIQPSPP-WSYDQSYQYLGSITSSSVHPATPISPGRASGMTSLSAELSSRLSTAPDLTAFGDP-----RQFPTLPSISD-----PRMHYP-GAFTYSP-PVTSGIGIGMS---------------------------AMSS-ASRYHTYLPPPYP-GSSQAQA-GPFQTG-------------------SPSYHLYYGASAGSYQFSMVG------GERSPP--------------------------------RILPPCTNASTGAALLNPSLPSQSD-VVETEGSHSNSPTNMPP-----------------------------------------ARLEEAVWRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01196-1", "uniprot_id": "RUNX1_HUMAN", "id": "Q01196-1", "name": "Runt-related transcription factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------MRIP-----------------------------------------VDASTS-------------------------RRFTPPSTALSPGKMSEALPLGAPDA-GAALAG---------------------------------------------KLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLD----------DQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPP-WSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDP-----RQFPALPSISD-----PRMHYP-GAFTYSPTPVTSGIGIGMS---------------------------AMGS-ATRYHTYLPPPYP-GSSQAQG-GPFQAS-------------------SPSYHLYYGASAGSYQFSMVG------GERSPP--------------------------------RILPPCTNASTGSALLNPSLPNQSD-VVEAEGSHSNSPTNMAPS----------------------------------------ARLEEAVWRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JET8-1", "uniprot_id": "A0AC58JET8_DANRE", "id": "A0AC58JET8-1", "name": "Runt-related transcription factor", "aln": "----------------------------------------------------------------------------------------------------------------MHRVPGQNRLAGPTQADRGVPAVGQIREPFKIREQIKLEALDSDEDVDKQTLPMASNSIFESFQSYQSCFSREPAPGRRFTPPSTTLSSGKMSEGLPLGAQESTGAALVG---------------------------------------------KLRMADRSMVEVLSDHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDIPDGTLVTVMAGNDENYSAELRNATAAIKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYQRAIKITVDGPREPRRHRQKPD----------EAVKPGALAFSE------QLRRSAMRCSPHH-GPAPNTRPTLN-TPPFGSPAHSQIPDSRQMQTSPS-WSYEQSYPYLGPISTPAVHPTTPISPNRTA-------------LHCPELTAFTDPRVGLERSFPSLPSLPDGRFSDPRVPYPTGAFTYTPTPVTSAIGIGMS---------------------------AMSSPAGRYHTYLPPAYPAGSSQAQA-GAFQAS-------------------SSPYHLYYSSAAGSYQFSMMPSGGAAAGERSPP--------------------------------RILP-CTNASTGSALLHPSLPNQSEGVVEAEGSHSSSPTSMSV---------------------------------------------EAVWRPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W349-1", "uniprot_id": "LOZEN_DROME", "id": "Q9W349-1", "name": "Protein lozenge", "aln": "MHLHLLAAEKTPPSPSPNPTPTPSASPSGHTGAAGESQLDLASQTESQLQLGLPLASGYGLGLGLGLGLGLGLGQELVADHSTTVAPVSVAGPGRLGRSINGSGGSHHHHHLHHHYSPYHHAHPYHPPHPHAPHHHHHHHPPYPYPPAGPHPPAMVTSSSTSPTGNGWSSSTGDFKGITAVATATGGGVGGATQGATASTGATAAEVLAVSSSASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNNNNAVHQDLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRSKTSPTGGPHYRALGLGQRPYIDGFPSTKALHELESLRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNSTINSDCQVYKPNAPHIQAAEMMGAGEWTNGSSS--SAAAYYHSHAHHPHAHHAHAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAAHLPAVLPEMHGHGFATDPYQTAGYGGGNTGGGSASKSELDYGGSYNQAWSNGYQNYQYGSCLATAQYGPQAAPPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQYLGTATSADHLTIGSLTGSSRSSIEIGQDQYHQQVHHAQQQQQQQQQQQQVHHPQQQQVESAGEVGGSGAGGVESAREEDVGDLSQVWRPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .. * :*: : .. :* *.:.: . *.: .* :* : : :********..* ****.**:***.*****:*******.:: *** **: ****** .***** *: :**:**:********************** *.******* :***:********* : . . : ..:. :: .***:* : ..:. . .: : . . . : :. : . : ::: * :.*... . : * .. : : . .. .:: : . . .* *.:: :.:*:. * . : :* ::**. * .:. . ..:*:. . .*: :. . .**:. : :** :: .*::. * **...* :* .: . . . . *****", "identical_positions": 132, "similar_positions": 145, "identity": "15.94%" }, { "cls_id": "homologset.agr.FB:FBgn0002579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14455-1", "uniprot_id": "RL36B_YEAST", "id": "O14455-1", "name": "Large ribosomal subunit protein eL36B", "aln": "MAVKTGIAIGLNKGKKVT------------------------QMTPAPKISYKK-GAASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05745-1", "uniprot_id": "RL36A_YEAST", "id": "P05745-1", "name": "Large ribosomal subunit protein eL36A", "aln": "MTVKTGIAIGLNKGKKVT------------------------SMTPAPKISYKK-GAASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ABK0LZ43-1", "uniprot_id": "A0ABK0LZ43_RAT", "id": "A0ABK0LZ43-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZZ95-1", "uniprot_id": "D3ZZ95_RAT", "id": "D3ZZ95-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRRRGRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47964-1", "uniprot_id": "RL36_MOUSE", "id": "P47964-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M706-1", "uniprot_id": "F1M706_RAT", "id": "F1M706-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAMGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKKVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A1Q0-1", "uniprot_id": "D4A1Q0_RAT", "id": "D4A1Q0-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------------------KNVSKPRHSRRR-GRLTKHTKFVRDMIREVCG--------FAPYQRRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCN1-1", "uniprot_id": "M0RCN1_RAT", "id": "M0RCN1-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKSHKVT------------------------KNVSKTRHSRRR-GRLTKHTKFVRDMIPEVCG--------FAPYVRRTMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q415-1", "uniprot_id": "RL36_DANRE", "id": "Q6Q415-1", "name": "Large ribosomal subunit protein eL36", "aln": "MVVRYPMAVGLNKGHKVT------------------------KNVSKPKHSRRR-GRLTKHAKFARDLIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNTLAAMRKAAAKKE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49630-1", "uniprot_id": "RL36_DROME", "id": "P49630-1", "name": "Large ribosomal subunit protein eL36", "aln": "MAVRYELAIGLNKGHKTSKIRN--------------VKYTGDKKVKGLRGSRLK-NIQTRHTKFMRDLVREVVG--------HAPYEKRTMELLKVSKDKRALKFLKRRLG-THIR------AKRKREELSNILTQLRKAQTHAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HME6-1", "uniprot_id": "ALT36_HUMAN", "id": "C0HME6-1", "name": "RPL36 alternative reading frame protein", "aln": "MASEAEGAGTRGSGPRELSRYSPPPLLPVAVRSHGPTLPYGRGPQQGPQSDQEREQAQAQPTPRASDQTHQVRAGHDSGGVWLCPVRAARHGVTEGLQGQTGPQIYQEKGGDAHPRQEEAGGAEQRTGRHEESCCQERLSPSPALSLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * ... : : . : :. : . :: . .* : . : . :. :.: * :. * *: : . .: * ", "identical_positions": 7, "similar_positions": 33, "identity": "4.73%" }, { "cls_id": "homologset.agr.FB:FBgn0002590", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97461-1", "uniprot_id": "RS5_MOUSE", "id": "P97461-1", "name": "Small ribosomal subunit protein uS7", "aln": "------------------------MTEWEAATPAVAETP--DIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24050-1", "uniprot_id": "RS5_RAT", "id": "P24050-1", "name": "Small ribosomal subunit protein uS7", "aln": "------------------------MTEWETATPAVAETP--DIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAANGFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINARKGSSNSYAIKKKDELERVAKSNR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46782-1", "uniprot_id": "RS5_HUMAN", "id": "P46782-1", "name": "Small ribosomal subunit protein uS7", "aln": "------------------------MTEWETAAPAVAETP--DIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24186-1", "uniprot_id": "RS5A_DROME", "id": "Q24186-1", "name": "Small ribosomal subunit protein uS7A", "aln": "MAEVAENVVETFEEPAAPMEAEVAETILETNVVSTTELP--EIKLFGRWSCDDVTVNDISLQDYISVKEKFARYLPHSAGRYAAKRFRKAQCPIVERLTCSLMMKGRNNGKKLMACRIVKHSFEIIHLLTGENPLQILVSAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26783-1", "uniprot_id": "RS5_YEAST", "id": "P26783-1", "name": "Small ribosomal subunit protein uS7", "aln": "-MSDTEAPVEVQED--FEVVEEFTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQP--IFVAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLDIINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVNQAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: . :****.:** ::* ::* ** **: *:: ::.*:***** : ********:**** *:**:******** : **:**:::**::**.:**:*::*.** *:*****:**:* .*:.***************** ** *************** **:***** ****.******************", "identical_positions": 129, "similar_positions": 44, "identity": "56.09%" }, { "cls_id": "homologset.agr.FB:FBgn0002593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0H2UHJ3-1", "uniprot_id": "A0A0H2UHJ3_RAT", "id": "A0A0H2UHJ3-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELTCIYSDLILH--DEVMVTEDKINALIKAAGVNVELFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSTVAAP--AEEKKVEAKKEE-SEESEDDTSFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A494BA26-1", "uniprot_id": "A0A494BA26_MOUSE", "id": "A0A494BA26-1", "name": "Large ribosomal subunit protein P1", "aln": "MASASELACIYSALILHEDDEVMVTEDKINALIKAA--LIKPFWPSLFAKALANVNIGSLICSVGAGGPAPAAGAAPAGSPAPSTAAAP--AEEKKVETKKEE-SEEFEDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19944-1", "uniprot_id": "RLA1_RAT", "id": "P19944-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILH-DDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSAAAAP--AEEKKVEAKKEE-SEESEDDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05386-1", "uniprot_id": "RLA1_HUMAN", "id": "P05386-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILH-DDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGPAPSTAAAP--AEEKKVEAKKEE-SEESDDDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47955-1", "uniprot_id": "RLA1_MOUSE", "id": "P47955-1", "name": "Large ribosomal subunit protein P1", "aln": "MASVSELACIYSALILH-DDEVTVTEDKINALIKAAGVSVEPFWPGLFAKALANVNIGSLICNVGAGGPAPAAGAAPAGGAAPSTAAAP--AEEKKVEAKKEE-SEESEDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08570-1", "uniprot_id": "RLA1_DROME", "id": "P08570-1", "name": "Large ribosomal subunit protein P1", "aln": "MSTKAELACVYASLILV-DDDVAVTGEKINTILKAANVEVEPYWPGLFAKALEGINVKDLITNIGSG-----VGAAPAGGAAPAAAAAAPAAESKKEEKKKEEESDQSDDDMGFGLFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10622-1", "uniprot_id": "RLA3_YEAST", "id": "P10622-1", "name": "Large ribosomal subunit protein P1B", "aln": "MS-DSIIS--FAAFILA-DAGLEITSDNLLTITKAAGANVDNVWADVYAKALEGKDLKEILSGFHNAGPVAGAGAASGAAAAGGDAAAE--------EEKEEEAAEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05318-1", "uniprot_id": "RLA1_YEAST", "id": "P05318-1", "name": "Large ribosomal subunit protein P1A", "aln": "MSTESALS--YAALILA-DSEIEISSEKLLTLTNAANVPVENIWADIFAKALDGQNLKDLLVNFS-AGAAAPAGVAGGVAGGEAGEAEA--------EKEEEEAKEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : :: :: :** : :: ::: :: :** :. *..::**** . :: .:: .. . .*.* . . . . * * ::** :: :** .*****", "identical_positions": 23, "similar_positions": 43, "identity": "19.49%" }, { "cls_id": "homologset.agr.FB:FBgn0002609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "----------------------------------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQ---PATLY----------------------------------------------------------------------------------------------------------------------------------SSAAPGPLNSYLEGYRACLAR---------------LARVLPACSVLEPAVSARLLEH--------------------------------------LRQRT-----------------------VSDDSPSLT-LPPAP------------------APAP-----------------------------SPPVPP---------------------------PGSSGLWRPW-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCC6-1", "uniprot_id": "HES4_HUMAN", "id": "Q9HCC6-1", "name": "Transcription factor HES-4", "aln": "-------------------MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAA----------------------------------------------------------------------------------------------------------------------------------LSADPAVLGKYRAGFHECLAE---------------VNRFLAGCEGVPADVRSRLLGHLAA----------------------------------CLRQLG-----------------------PSRRPASLSPAAPAE------------------APAPEVYAGRPLLPSLG----------GPFPLLAPPLLPG-------------LTRALPAAPRAGPQGPGGPWRPWLR-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ70-1", "uniprot_id": "A0AB32TZ70_DANRE", "id": "A0AB32TZ70-1", "name": "", "aln": "-------------------MTPNIITEAHPHSFG----SRMTVAQR-KEAHELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTVRFLRDLP-----------------------------------------------------------------------------------------------------------------------------------------SSSAKGQTDSYKEGYKACLQR---------------ISTMLPQSN-LETEAHQRVSEFIHT----------------------------------CSSRWR-----------------------LLHRPARTAVLRTQK-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NTZ6-1", "uniprot_id": "A0A8M1NTZ6_DANRE", "id": "A0A8M1NTZ6-1", "name": "", "aln": "-------------------------------MDMTATKLQQNSCQLHISSKEERKLRKPLIERKRRERINLCLDQLRETVVAVFKPDQ---SKLEKADILEMTVKHLQNIQSSR-----------------------------------------------------------------------------------------------------------------------------------VSDPVLNTGARQRYSTGYIQCMQE---------------VHNLLHSCDWMDKTLGSRLLNHLFK----------------------------------SLP---------LSAKDCPRLPKTS-LTSVPSDHSEYSSFHVDE------------------TASPKPCSSSPFLCKR--------------PNQSQNQHFT-------------PIRMPHDVESSHLSV-LQMWRPW-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "---------------------------------MTASNMG-NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQ---SKLEKADVLEITVQHMENLQRGHGQGG-------------------------------------------------------------------------------------------------------------------------------SNSPGTGFESRQRYSSGYIQCMHE---------------VHNLLLSCPGMDKTLGARLLNHLLK----------------------------------SLPHISTEPSGTSSAGTSSPLPLSP-TQSPINLPSSLQPHALLL------------------SPSP-PSSPTHSLVRP--------------REQSSPPSSP-------------SPQSPASLPPFFPGVDPSMWRPW-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K6W4-1", "uniprot_id": "A0A0G2K6W4_RAT", "id": "A0A0G2K6W4-1", "name": "Transcription cofactor HES-6", "aln": "----------------------------MAPPQAPNRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELR--LLLAGTEVQ---AKLENAEVLELTVRRVQGALRGRARGEWRRGSRAGALTGHACHPR-------------------------------------------------------------------------------------------------AGHVGSRSLGPVHEREQLQAEASERFAAGYIQCMHE---------------VHTFVSTCQAIDATVSAELLNHLLE----------------------------------SMPLREGSSFRDLLGDSLAGLPGGSGRSSWPPGGSPESPLSSPP------------------GPGDDLCSDLEEIPEA--------------ELNRVPAEGP-------------DLVPTSLGILTTARRAQSVWRPW-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHE6-1", "uniprot_id": "HES6_MOUSE", "id": "Q9JHE6-1", "name": "Transcription cofactor HES-6", "aln": "----------------------------MAPSQAPSRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELR--LLLAGTEVQ---AKLENAEVLELTVRRVQGALRGRAR----------------------------------------------------------------------------------------------------------------------------------EREQLQAEASERFAAGYIQCMHE---------------VHTFVSTCQAIDATVSAELLNHLLE----------------------------------SMPLREGSSFQDLLGDSLAGLPGGSGRSSWPPGGSPESPLSSPP------------------GPGDDLCSDLEEIPEA--------------ELNRVPAEGP-------------DLVSTSLGSLTAARRAQSVWRPW-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HZ4-1", "uniprot_id": "HES6_HUMAN", "id": "Q96HZ4-1", "name": "Transcription cofactor HES-6", "aln": "----------------------------MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELR--LLLAGAEVQ---AKLENAEVLELTVRRVQGVLRGRAR----------------------------------------------------------------------------------------------------------------------------------EREQLQAEASERFAAGYIQCMHE---------------VHTFVSTCQAIDATVAAELLNHLLE----------------------------------SMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPP------------------GPGDDLCSDLEEAPEA--------------ELSQAPAEGP-------------DLVPAALGSLTTAQIARSVWRPW-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TA89-1", "uniprot_id": "HES5_HUMAN", "id": "Q5TA89-1", "name": "Transcription factor HES-5", "aln": "-------------------------------------MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAVSYLKHSKAFVAAAG-------------------------------------------------------------------------------------------------------------------------------------PKSLHQDYSEGYSWCLQE---------------AVQFLTLHAASDT--QMKLLYHFQ---------------------------------------------------------------RPPAAPAAPAKEPKAP------------------GAAPPPALSAKATAAA--------------AAAHQPACG--------------------------------LWRPW-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35779-1", "uniprot_id": "BHE41_RAT", "id": "O35779-1", "name": "Class E basic helix-loop-helix protein 41", "aln": "MDEGIPHLQ-------ERQLLEHRDFIGLDYSSLY-MCKPKRSLKR-DDTKDTYKLPHRLIEKKRRDRINECIAQLKD-LLPEHLKLTTLG-HLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERS--LKSP-VQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRCAQLVSHLHAVAT------QLLTPQVTPGRGPGRAPCSAG-----AAAASGSER-------VARCVPVIQRTQP-GTEP--EHDTDTDSGYGGEAEQ------------GRAAVKQEPPGDPSAAPKRLKLEARG----------------ALLGPEP-----------ALLGSLVALGGG----APFAQP--AAAPFCLPFYLLSP-SAAAYVQPWLDKSGLDKYLYP-AAAAPFPLLYPGIPA--------AAAAAAAAAFPCLSSVLSPPPEKAGSAAGAPFLAHEVAPPGSLRPQHAHSRTHLPHA-----VNPES-SQEDATQPAKDAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PV5-1", "uniprot_id": "BHE41_MOUSE", "id": "Q99PV5-1", "name": "Class E basic helix-loop-helix protein 41", "aln": "MDEGIPHLQ-------ERQLLEHRDFIGLDYSSLY-MCKPKRSLKR-DDTKDTYKLPHRLIEKKRRDRINECIAQLKD-LLPEHLKLTTLG-HLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERS--LKSP-VQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRCAQLVSHLHAVAT------QLLTPQVPSGRGSGRAPCSAG-----AAAASGPER-------VARCVPVIQRTQP-GTEP--EHDTDTDSGYGGEAEQ------------GRAAVKQEPPGDSSPAPKRPKLEARG----------------ALLGPEP-----------ALLGSLVALGGG----APFAQP--AAAPFCLPFYLLSP-SAAAYVQPWLDKSGLDKYLYP-AAAAPFPLLYPGIPA--------AAAAAAAAAFPCLSSVLSPPPEKAGATAGAPFLAHEVAPPGPLRPQHAHSRTHLPRA-----VNPES-SQEDATQPAKDAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0J9-1", "uniprot_id": "BHE41_HUMAN", "id": "Q9C0J9-1", "name": "Class E basic helix-loop-helix protein 41", "aln": "MDEGIPHLQ-------ERQLLEHRDFIGLDYSSLY-MCKPKRSMKR-DDTKDTYKLPHRLIEKKRRDRINECIAQLKD-LLPEHLKLTTLG-HLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERS--LKSP-IQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCVQLINHLHAVATQFLPTPQLLTQQVPLSKGTG-APSAAG-----SAAAPCLERAGQKLEPLAYCVPVIQRTQP-SAELAAENDTDTDSGYGGEAEARPDREKGKGAGASRVTIKQEPPGEDSPAPKRMKLDSRGGGSGGGPGGGAAAAAAALLGPDPAAAAALLRPDAALLSSLVAFGGGG--GAPFPQPAAAAAPFCLPFCFLSPSAAAAYVQPFLDKSGLEKYLYPAAAAAPFPLLYPGIPAPAAAAAAAAAAAAAAAAFPCLSSVLSPPPEKAGAAA-ATLLPHEVAPLGAPHPQHPHGRTHLPFAGPREPGNPESSAQEDPSQPGKEAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35780-1", "uniprot_id": "BHE40_RAT", "id": "O35780-1", "name": "Class E basic helix-loop-helix protein 40", "aln": "MER-IPSAQPPPTCLPKTPGLEHGDLSGMDFAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKD-LLPEHLKLTTLG-HLEKAVVLELTLKHVKALTNLIDQQQQKIMALQSGLQAGDLSGKNIEAGQEMFCSGFQTCAREVLQYLAKHEN--TRDLKSSQLVTHLHRVVS------ELLQGSAS-RKPLDSAPKPVDFKEKPSFLAKGSEG------PGKNCVPVIQRTFAPSGGEQSGSDTDTDSGYGGELEK--------------GDLRSEQPYFKSDHGRRFTVGERVS-------------TIKQESEEPPTK----KSRMQLSDEEGHFVGSDLMGSPFLGPHPHQPPFCLPFYLIPP-SATAYLP------MLEKCWYP----TSVPLLYPGLNT----------SAAALSSFMNPDKIPTP-----------LLLPQRLPSPL-AHSSLDSSALLQALK-----------QIPPLNLETKD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35185-1", "uniprot_id": "BHE40_MOUSE", "id": "O35185-1", "name": "Class E basic helix-loop-helix protein 40", "aln": "MER-IPSAQPPPTCLPKAPGLEHGDLSGMDFAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKD-LLPEHLKLTTLG-HLEKAVVLELTLKHVKALTNLIDQQQQKIIALQSGLQAGDLSGRNLEAGQEMFCSGFQTCAREVLQYLAKHEN--TRDLKSSQLVTHLHRVVS------ELLQGGAS-RKPLDSAPKAVDLKEKPSFLAKGSEG------PGKNCVPVIQRTFAPSGGEQSGSDTDTDSGYGGELEK--------------GDLRSEQPYFKSDHGRRFAVGERVS-------------TIKQESEEPPTK----KSRMQLSEEEGHFAGSDLMGSPFLGPHPHQPPFCLPFYLIPP-SATAYLP------MLEKCWYP----TSVPVLYPGLNT----------SAAALSSFMNPDKIPTP-----------LLLPQRLPSPL-AHSSLDSSALLQALK-----------QIPPLNLETKD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14503-1", "uniprot_id": "BHE40_HUMAN", "id": "O14503-1", "name": "Class E basic helix-loop-helix protein 40", "aln": "MER-IPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKD-LLPEHLKLTTLG-HLEKAVVLELTLKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHEN--TRDLKSSQLVTHLHRVVS------ELLQGGTS-RKPSDPAPKVMDFKEKPSSPAKGSEG------PGKNCVPVIQRTFAHSSGEQSGSDTDTDSGYGGESEK--------------GDLRSEQPCFKSDHGRRFTMGERIG-------------AIKQESEEPPTK----KNRMQLSDDEGHFTSSDLISSPFLGPHPHQPPFCLPFYLIPP-SATAYLP------MLEKCWYP----TSVPVLYPGLNA----------SAAALSSFMNPDKISAP-----------LLMPQRLPSPLPAHPSVDSSVLLQALK-----------PIPPLNLETKD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04667-1", "uniprot_id": "HES3_RAT", "id": "Q04667-1", "name": "Transcription factor HES-3", "aln": "------------------------------------------------------------MEKKRRARINLSLEQLRS-LLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQG----LWLVPS---------------------------------------------------------------------------------------------------------------------------------GVDYPSGFRGGLPG---------------SSQRLRPG-EDDSGLRCPLLLQRR-----------------------------------AGSTTDSANP--QTASVLSP-------CLPAIWAPGPPAGGSQS------------------PQSPFPPLGGLL------------------ESSTGILAP----------------PPASNCQAENPRPGFRVWRPW-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61657-1", "uniprot_id": "HES3_MOUSE", "id": "Q61657-1", "name": "Transcription factor HES-3", "aln": "------------------------------------------------------------MEKKRRARINVSLEQLRS-LLERHYSHQIRKRKLEKADILELSVKYMRSLQNSLQG----LWPVPS---------------------------------------------------------------------------------------------------------------------------------GVDYPSGFQGGLRG---------------VSQRLRPG-EGDSGLRCPLLLQRR-----------------------------------EGSTTDSANP--QATSVLNP-------CLPAIWAPSRAAGGSHS------------------PQSPLPLPGGLL------------------ESSTDVVAP----------------HPASNCQAESTRPGFRVWRPW-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TGS1-1", "uniprot_id": "HES3_HUMAN", "id": "Q5TGS1-1", "name": "Transcription factor HES-3", "aln": "------------------------------------------------------------MEKKRRARINVSLEQLKS-LLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQG----LWPVPR---------------------------------------------------------------------------------------------------------------------------------GAEQPSGFRSCLPG---------------VSQLLRRGDEVGSGLRCPLVPESA-----------------------------------AGSTMDSAGLGQEAPALFRP-------CTPAVWAPAPAAGGPRS------------------PPPLLLLPESLP------------------GSSASVPPP----------------QPASSRCAESPGLGLRVWRPWG----------SPGDDLN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01068-1", "uniprot_id": "ESM3_DROME", "id": "Q01068-1", "name": "Enhancer of split m3 protein", "aln": "------------------------------------------MVMEMSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQGVVAGVG-----------------------------------------------------------------------------------------------------------------------SPPTSTSTAHVESFRSGYVHAADQ---------------ITQVLLQTQQTDEIGRKIMKFLSTR--------------------------------LIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAA------------------ISYSSFLTSKDE------------------LIDVTSVDGN-------------ALSETASVSSQESGASEPVWRPW-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: ** *** .: .*: : :**:* :**::: :. *: : ", "identical_positions": 13, "similar_positions": 17, "identity": "2.57%" }, { "cls_id": "homologset.agr.FB:FBgn0002622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62909-1", "uniprot_id": "RS3_RAT", "id": "P62909-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDP-SGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62908-1", "uniprot_id": "RS3_MOUSE", "id": "P62908-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDP-SGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23396-1", "uniprot_id": "RS3_HUMAN", "id": "P23396-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDP-TGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06559-1", "uniprot_id": "RS3_DROME", "id": "Q06559-1", "name": "Small ribosomal subunit protein uS3", "aln": "MNANLPISKKRKFVSDGIFKAELNEFLTRELAEDGYSGVEVRVTPSRTEIIIMATKTQQVLGEKGRRIRELTAMVQKRFNFETGRIELYAEKVAARGLCAIAQAESLRYKLTGGLAVRRACYGVLRYIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPCNDYVETATRHVLLRQGVLGIKVKVMLPYDP-KNKIGPKKPLPDNVSVVEPKEEKIYETPETEYKIPPPSKPLDDLSEAKVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05750-1", "uniprot_id": "RS3_YEAST", "id": "P05750-1", "name": "Small ribosomal subunit protein uS3", "aln": "--MVALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMR--DPAKSRTGP-KALPDAVTIIEPKEEEPILAPSVKDYRPAEETEAQAEPVEA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:*:**:* ******:******:***********::**:** **:**:****:****.*** :***** : * : ****:* ***.*:*****:::** .***:***.***:*::*****************. ***:***.**::****:* * :::**.****:**********:* ** ..: ** *.*** *:::***:* :* : . . ", "identical_positions": 146, "similar_positions": 51, "identity": "59.11%" }, { "cls_id": "homologset.agr.FB:FBgn0002626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M9W1-1", "uniprot_id": "A0ABK0M9W1_RAT", "id": "A0ABK0M9W1-1", "name": "", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHDVKELEVLLMCNKSYCAEIAHNVSSKNRKAI--------IRVTNPNARLRSEENE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62910-1", "uniprot_id": "RL32_HUMAN", "id": "P62910-1", "name": "Large ribosomal subunit protein eL32", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62911-1", "uniprot_id": "RL32_MOUSE", "id": "P62911-1", "name": "Large ribosomal subunit protein eL32", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62912-1", "uniprot_id": "RL32_RAT", "id": "P62912-1", "name": "Large ribosomal subunit protein eL32", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZWL0-1", "uniprot_id": "D3ZWL0_RAT", "id": "D3ZWL0-1", "name": "", "aln": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17932-1", "uniprot_id": "RL32P_MOUSE", "id": "P17932-1", "name": "Putative large ribosomal subunit protein eL32'", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKWNWRKPRGIDNRVRRRFKGQILMPNIGYRSNKKTKHTLSSGFRKFLVHNIKEPEVLLMCNKSYRAEIAHNVSSKNRKAIVERAAQLAIRVTNPNTRLHSEENE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y5C9-1", "uniprot_id": "A0A8I5Y5C9_RAT", "id": "A0A8I5Y5C9-1", "name": "", "aln": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04359-1", "uniprot_id": "RL32_DROME", "id": "P04359-1", "name": "Large ribosomal subunit protein eL32", "aln": "-MTIRPAYRPKIVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHGVSSKKRKEIVERAKQLSVRLTNPNGRLRSQENE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38061-1", "uniprot_id": "RL32_YEAST", "id": "P38061-1", "name": "Large ribosomal subunit protein eL32", "aln": "MASLP---HPKIVKKHTKKFKRHHSDRYHRVAENWRKQKGIDSVVRRRFRGNISQPKIGYGSNKKTKFLSPSGHKTFLVANVKDLETLTMHTKTYAAEIAHNISAKNRVVILARAKALGIKVTNPKGRLALEA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : **::*:**:* **:**** :: :*** :**:. *****:*: *:*** .**:*:. .: .:.*** :::: *.* * .: * .****.:*:*:* * :::** : ** ", "identical_positions": 49, "similar_positions": 42, "identity": "36.3%" }, { "cls_id": "homologset.agr.FB:FBgn0002631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCS------TEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRT--------------VSG-----------GPPSLTPASASAPAP--------------------SPPVP----PPSSLG----------LWRPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATLYS------SAAPGPLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRT--------------VSD-----------DSPSLTLPPAPAPAP--------------------SPPVP----PPGSSG----------LWRPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y543-1", "uniprot_id": "HES2_HUMAN", "id": "Q9Y543-1", "name": "Transcription factor HES-2", "aln": "------------MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPASSWP------TAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRA--------------ASATLDGGRAGDSSGPSAPAPAPASAPEPA-------------------SAPVPSPPSPPCGPG----------LWRPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "------MTASNMGNGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQS---KLEKADVLEITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSPPSSPTHSLVRPR---EQSSPPSSPSPQSPASLPPFFPG-VDPSMWRPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q96HZ4-1", "uniprot_id": "HES6_HUMAN", "id": "Q96HZ4-1", "name": "Transcription cofactor HES-6", "aln": "MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELR--LLLAGAEVQA---KLENAEVLELTVRRVQGVLRGRAR---EREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRS--GWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13096-1", "uniprot_id": "ESM5_DROME", "id": "P13096-1", "name": "Enhancer of split m5 protein", "aln": "-------MAPQSNNSTTFVSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQG--DDAILRMDKAEMLEAALVFMRKQVVKQQAP------VSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQR-------------MLQADQVQTSVTTSTPRPLSPASSGYHSD------------------NEDSQSAASPKPVEET----------MWRPW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * ***:*::** *:*..*. *: : ::::*::** :: :. . : : ** .: .: .: :. :. :: ** . . . : . . . * :****", "identical_positions": 23, "similar_positions": 44, "identity": "9.83%" }, { "cls_id": "homologset.agr.FB:FBgn0002633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "---------------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLR---EQPAS---------------------------------VCSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSGGP---PSLTPASASAPAPSP-----------------------------------------------------------------------------------------PVPPPSSL-------------GLWRPW--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "---------------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQ---EQPAT---------------------------------LYSSAAPGPLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSDDS---PSLTLPPAPAPAPSP-----------------------------------------------------------------------------------------PVPPPGSS-------------GLWRPW--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCC6-1", "uniprot_id": "HES4_HUMAN", "id": "Q9HCC6-1", "name": "Transcription factor HES-4", "aln": "MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVT---------------------------------AALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAP-------------------------------------------EVYAGRPLLPSLGGPFPLLAP--------PLLPGLTR-------ALPAAPRAGP-QG--------PGGPWRPWLR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14469-1", "uniprot_id": "HES1_HUMAN", "id": "Q14469-1", "name": "Transcription factor HES-1", "aln": "MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMT---------------------------------AALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLT--------ADSMWRPWRN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NTZ6-1", "uniprot_id": "A0A8M1NTZ6_DANRE", "id": "A0A8M1NTZ6-1", "name": "", "aln": "------------MDMTATKLQQNSCQLHISSKEERKLRKPLIERKRRERINLCLDQLRETVVAVFKPD---QSKLEKADILEMTVKHLQNIQSSR----------------------------------VSDPVLNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLLNHLFKSLP---------LSAKDCPRLPKTS------------------------------------------------LTSVPSDHSEYSSFHVDETASPKPCSSSPFLCKRPNQSQNQHFTPIRMPHDV-ESSHLSV-LQMWRPW--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "--------------MTASNMG-NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLD---QSKLEKADVLEITVQHMENLQRGHGQ------------------------------GGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSP------------------------------------------------TQSPINLPSSLQPHALLLSPSP-PSSPTHSLVRPREQSSPPSSPSPQSPASL-PPFFPGVDPSMWRPW--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13097-1", "uniprot_id": "ESM7_DROME", "id": "P13097-1", "name": "Enhancer of split m7 protein", "aln": "---------------MATKYEMS------KTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTG--DAKFEKADILEVTVQHLRKLKESK-------------------------------------KHVPANPEQSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLN----------QLEQPMEQPQAV------------------------------------------------NTPLSIVCGSSSSSSTYSSASS---CSSISPVSSGYASDNESLLQISSPG------------QVWRPW--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0G2K6W4-1", "uniprot_id": "A0A0G2K6W4_RAT", "id": "A0A0G2K6W4-1", "name": "Transcription cofactor HES-6", "aln": "---------MAPPQAPNRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELRLLLAG---TEV--QAKLENAEVLELTVRRVQGALRGRARGEWRRGSRAGALTGHACHPRAGHVGSRSLGPVHEREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLNHLLESMPLREGSSFRDLLGDSLAGLPGGS------------------------------------------------GRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVPTSLGILTTARRAQSVWRPW--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TGS1-1", "uniprot_id": "HES3_HUMAN", "id": "Q5TGS1-1", "name": "Transcription factor HES-3", "aln": "-----------------------------------------MEKKRRARINVSLEQLKSLLEKHYSHQIR-KRKLEKADILELSVKYMRSLQNSLQG------------------------------------LWPVPRGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAG---LGQEAPALFRPCTP------------------------------------------------------------AVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPWGSPGDDLN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::** *** .* :*: : *:*:*::**::*: :. *: . : : : . *: . . **** ", "identical_positions": 20, "similar_positions": 25, "identity": "6.12%" }, { "cls_id": "homologset.agr.FB:FBgn0002638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VE37-1", "uniprot_id": "RCC1_MOUSE", "id": "Q8VE37-1", "name": "Regulator of chromosome condensation", "aln": "---MPPKRIAKRRSP-----------------------------------------------PEDAIP-------------------KSK------------KVKVSHRSHNTEPGLVLTLGQGDVGQLGLG--ESVLERKKPALVPLLQ----DVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTS---------------------VEGSEMVPGKVELQ--------EKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQLDAPVVKVASGNDHLVMLTNDGDLYTLGCGEQGQLGRVPELFANRGGRQGLGRLLVPRCVLLKSRGTRGRVRFQDAFCGAYFTFA-ISREGHVYGFGLSNYHQLGTPG--TGSCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLG-------------EGAEEKSIPTLISRLP-VVSSVACGASVGYAVSKDGRVFAWGMGTNYQLGTG-QDEDAWSPVEMTGKQLENRVVLTVSSGGQHTVLLVKDQAQS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEW5-1", "uniprot_id": "A0A8I6AEW5_RAT", "id": "A0A8I6AEW5-1", "name": "Regulator of chromosome condensation", "aln": "MAPCPVQPLCSRNGPGSQGHTLGEGTGIPLTVEGCGRLSLATKRPCTTHWLAHTSLLTVPSRPSEAVKYAALLTEGAVCFPPLFGSWKSQPGVEGISDGSRYANSVSHRSHNTEPGLVLTLGQGDVGQLGLG--ESVLERKKPALVPLLQ----DVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTS---------------------VEGSEMVPGKVELQ--------EKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQLDTQVVKVASGNDHLVMLTTDGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPRCVLLKSRGTRGRVRFQDAFCGAYFTFA-ISREGHVYGFGLSNYHQLGTPG--TGSCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLG-------------EGAEEKSIPTLISRLP-VVSSVACGASVGYAVSKDGRVFAWGMGTNYQLGTG-QEDDAWSPVEMTGKQLENREVLTVSSGGQHTVLLVKDKTQS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18754-1", "uniprot_id": "RCC1_HUMAN", "id": "P18754-1", "name": "Regulator of chromosome condensation", "aln": "---MSPKRIAKRRSP-----------------------------------------------PADAIP-------------------KSK------------KVKVSHRSHSTEPGLVLTLGQGDVGQLGLG--ENVMERKKPALVSIPE----DVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTS---------------------VEGSEMVPGKVELQ--------EKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFA-ISHEGHVYGFGLSNYHQLGTPG--TESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLG-------------EGAEEKSIPTLISRLP-AVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTG-QDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25171-1", "uniprot_id": "RCC1_DROME", "id": "P25171-1", "name": "Regulator of chromosome condensation", "aln": "---MPRRKALTNNNNAG---------------------------------------------EAEQQPP------------------KAKR--------ARIAFHLELPKRRTVLGNVLVCGNGDVGQLGLG--EDILERKRLSPVAGIP----DAVDISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTS---------------------EDGSESKPDLIDLP--------GKALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTID---GNK-RTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQLIITRAKP-----FEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHET--KGKEFA---LTPIKTELKDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLG-------------DVKDVVEKPTIVKKLTEKIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVG-DGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLVKADKQDQKENVPVKVSGSSSISKKDKTPPQDNVDKEAENVDKQEQKENLPAKASTSSKKNKTPPQDNADKEAENVDKQEQKENLPAKASTSSKKIKTPPQDDAAEEVEEESAQEPTPKKAKKPAAKRGGKKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21827-1", "uniprot_id": "RCC1_YEAST", "id": "P21827-1", "name": "Guanine nucleotide exchange factor SRM1", "aln": "---MVKRTVATNGDASG-------------------------------------------AHRAKKMS-------------------KTHAS-----HIINAQEDYKHMYLSVQPLDIFCWGTGSMCELGLGPLAKNKEVKRPRLNPFLPRDEAKIISFAVGGMHTLALDEESNVWSWGCNDVGALGRDTSNAKEQLKDMDADDSSDDEDGDLNELESTPAKIPRESFPPLAEGHKVVQLAATDNMSCALFSNGEVYAWGTFRCNEGILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFR-------LKTLDPRPFGLR--------HVKYIASGENHCFA-LTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPTKLNNVP-KFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEVPTRIKNTATQDHNIILVGCGGQFSVSGGVKLSDEDAEKRADEMDD-------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . *:: . . :: * *.: :**** . * *: . . :. .****.: * :..:::*:**** ******** : * * : *.: ::* *. :..* .:*.*: **:** ..* :*: :* : .:*.* **:::* * ::: * .:*.**** * * . : .: . * :: : . **.:: * . : . ::.*:**:: : : . ** : .:*: ** :..:. . **..* . **: :* ::** * . :* * :* * : .. :.: :: .. ***.:: :. ", "identical_positions": 84, "similar_positions": 122, "identity": "12.28%" }, { "cls_id": "homologset.agr.FB:FBgn0002641", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L8U6-1", "uniprot_id": "A0ABK0L8U6_RAT", "id": "A0ABK0L8U6-1", "name": "Molybdenum cofactor sulfurase", "aln": "MACGATERGPEPPAFQRHPEASAPRLAHGYGLRSMSELRDQEFGRLAG--TVYLDHAGATLFPQSQLTNFTKDLMENVYGNPHSQNITSKLTHDTVEQVRYRVLTHFHTTPEDYSVIFTAGSTAALRLVAETFPWVSRSPENSGSHFCYLTDNHTSVVGMRTVAATMNVTSTPVKPEDMWS-AEGKGAGACDPDCQLP--HLFCYPAQSNFSGTRYPLSWIDEVKSGQRS-PVRAP------------GKWFVLLDAASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALLVNKRVAPLLRKG-YFGGGTAAVYLAGEDFYIPRSSVAERFEDGTISFLDVIALKHGFDVLERLTG------GMVNIQQHTFALLHFTHSALSSLRYPNGAPVVRIYGDSGFSSPDVQGPIINFNVLDDAGKIIGYSQVDKMASLYNIHLRTGCFCNLGACQRHLGLSEEMVKKHFQ-AGHVCGDDVDIIDGRPTGSVRISFGYMSTLEDAQAFLRFISTIYLRSPGGQPVPQAS--TSDTGVLSSKSDCQ-----------SPQEGPCADPAVSSGSYPDINTVDLDLSQSKASSIQPIPQEKVAGILNGDLGSHIVTNIYLYPIKSCAAFEVTK---WPVGSQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPCIDLQQKVMVIKAEGMEPIQVPLEEDGERTQIC--QSRVCADRVNTYDCGENVSRWLSKFCGRP-CHLIKQSPHFQRNAKKTPKQGHPPGTAVALSLVNEAQYLLVNTSSVLELQQQLNASDERGKEESFS-VKDLISRFRANIITKGARAFEEEQWDEISIGSLHFQGQASLLPQAFALLSLLLTTLLLDLDSEVAFLEAAQQYNSTWHTACISRADHTGCRPCLLFPSMPQRPRASWLSQFPPGSGSNSPVVFL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14CH1-1", "uniprot_id": "MOCOS_MOUSE", "id": "Q14CH1-1", "name": "Molybdenum cofactor sulfurase", "aln": "MACGAAERGPEPPAFQRHLEASTQRLAHGYGLRSMSELRDQEFGRLAG--TVYLDHAGATLFPQSQLTNFTKDLMENVYGNPHSQNITSKLTHDTVEQVRYRILTHFHTTPEDYIVIFTAGSTAALRLVAEAFPWVSRSPENSGSHFCYLTDNHTSVVGMRKVAAAMSVTSIPVKPEDMWS-AEGKDAGACDPDCQLP--HLFCYPAQSNFSGTRYPLSWVEEVKSGRRS-PVNAP------------GKWFVLLDAASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALLVNKHVAPLLRKG-YFGGGTAAAYLAGEDFYVPRSSVAERFEDGTISFLDVIALKHGFDALEHLTG------GMVNIQQHTFALVQYTHSALSSLRYLNGAPVVRIYSDSEFSSPDVQGPIINFNVLDDGGKIIGYSQVDKMASLYNIHLRTGCFCNLGACQRHLGLSDEMVKKHFQ-AGHVCGDDVDIIDGRPTGSVRISFGYMSTLEDAQAFLRFISTIYLRSPSDQPVPQAS--ISDAGALTSKSDCH-----------SPQEGSCTDPSVCNGSYPDTNIMDLHPSLSKASSAQQTPQDKAAGILNGDPGSHIVTNIYLYPIKSCAAFEVTK---WPVGSQGLLYDRSWMVVNHNGICMSQKQEPRLCLIQPFIDLQQRIMVIKAEGMEPIQVPLEEDGEQTQIC--QSRVCADRVNTYDCGENVSRWLSKFLGRL-CHLIKQSPHFQRNARKTPKKGQPPGTTVALSLVNEAQYLLVNTSSILELQRQLNASDEHGKEESFS-MKDLISRFRANIITKGARAFEEEKWDEISIGSLHFQ-----------VLGPCHRCQMICIN-----QQTGQRNQDVFQTLSESRGRKVNFG-VYLMHSYLDLSSPCFLSVGSEVLPVLKDCGVS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EN8-1", "uniprot_id": "MOCOS_HUMAN", "id": "Q96EN8-1", "name": "Molybdenum cofactor sulfurase", "aln": "MAGAAAESGRELWTFAGSRDPSAPRLAYGYGPGSLRELRAREFSRLAG--TVYLDHAGATLFSQSQLESFTSDLMENTYGNPHSQNISSKLTHDTVEQVRYRILAHFHTTAEDYTVIFTAGSTAALKLVAEAFPWVSQGPESSGSRFCYLTDSHTSVVGMRNVTMAINVISTPVRPEDLWS-AEERSASASNPDCQLP--HLFCYPAQSNFSGVRYPLSWIEEVKSGRLH-PVSTP------------GKWFVLLDAASYVSTSPLDLSAHQADFVPISFYKIFGFPTGLGALLVHNRAAPLLRKT-YFGGGTASAYLAGEDFYIPRQSVAQRFEDGTISFLDVIALKHGFDTLERLTG------GMENIKQHTFTLAQYTYVALSSLQYPNGAPVVRIYSDSEFSSPEVQGPIINFNVLDDKGNIIGYSQVDKMASLYNIHLRTGCFCNTGACQRHLGISNEMVRKHFQ-AGHVCGDNMDLIDGQPTGSVRISFGYMSTLDDVQAFLRFIIDTRLHSSGDWPVPQAHADTGETGAPSADSQADVIPAVMGRRSLSPQEDALTGSRVWNNSS-TVNAVPVAPPVCDVARTQPTPSEKAAGVLEGALGPHVVTNLYLYPIKSCAAFEVTR---WPVGNQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPFIDLRQRIMVIKAKGMEPIEVPLEENSERTQIR--QSRVCADRVSTYDCGEKISSWLSTFFGRP-CHLIKQSSNSQRNAKKKHGKDQLPGTMATLSLVNEAQYLLINTSSILELHRQLNTSDENGKEELFS-LKDLSLRFRANIIINGKRAFEEEKWDEISIGSLRFQ-----------VLGPCHRCQMICID-----QQTGQRNQHVFQKLSESRETKVNFG-MYLMHASLDLSSPCFLSVGSQVLPVLKENVEGHDLPASEKHQDVTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2VD33-1", "uniprot_id": "MOCOS_DANRE", "id": "A2VD33-1", "name": "Molybdenum cofactor sulfurase", "aln": "MDTRSLQDFQDLCTFDVFKSFGHY---YGYG-VDQQALIDQEFKRIKG--VTYLDHAGTTLFPESLIKGFHDDISRNVYGNPHSHNSSSRLTHDTVESVRYKILAHFNTSPEDYSVIFTSGCTAALKLVADTFPWKPMSNKEPGSQFCYLTDNHTSVVGIRGATALQGVGTISVSPREVETRARNKTQTNGEEECSTP--HLFCYPAQSNFSGRKYSLSYVKGIQSQQLY-PACEHH-----------GQWFVLLDAACFVSCSPLDLSQYPADFVPISFYKMFGFPTGLGALLVRNEAAEVLRKT-YFGGGTAAAYLVEENYFIPKPNLASRFEDGTISFLDIISLHHGFETLQKLTG------SMTNIQLHTFGLARYTYTVLSCLCHSNGKHVAQIYCDNDFQSIAEQGAIINFSLLDCHGRTVGYSQVDKMASLFNIHIRTGCFCNTGACQHYLAISNQNVKSNLH-AGHICGDNIDLVDGRPTGSLRVSFGYMSSFEDCQNFLRFVVNCFVDKP--LILDQTKLAKLNSAAPIEPSSSY-----------SPSPDRMAVSEVTMS---------------------------KDGKKDGS--SCTLTNLFIFPVKSCASFEVTE---WPLGPQGLLYDRLWMVVNENGVCLSQKREPKLCLIQPVVCLAANTLKLQISGSEAITVPLDPSLEKSDLRTSQSKVCGDRVQTVDCGEEVSAWLSEFLGKP-CRLIRQRPEFLRDMKFGQGDCCP----TPLSLVNEAQFLLINRASVCFLQEAIANRYNSDNEETWRDTEQLVQRFRANLVISAQEPFAEDNWSHLTIGNTQFQ-----------VIGKCGRCQMIGVD-----QKTATRTQEPLRSLSECRSGKVTFG-VYLAHQSARNSTHPVLSIGSHVIPKISDSTDKF-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRA2-1", "uniprot_id": "MOCOS_DROME", "id": "Q9VRA2-1", "name": "Molybdenum cofactor sulfurase", "aln": "MTSYRPEFS-----------------------ASEQSQIDAEFSRLASNKSVYLDHAGTTLYAESQVTAAAEQLQRNVICNPH----TCRLTGDFVDQVRFKILEFFNTTAEDYHVIFTANATAALSLVAENFDFGSSG------EFHFCQENHTSVLGMR---ERVRENGIYMLRENEISGGKHKANGKVHEVSGKTGNSLLTFSAQCNFSGYKIPLEVIEQIQIDGLAKPGKELWSSLGEKKKNMHNDYYICLDAASFVATSPLDLQKYRPDYVCLSFYKIFGYPTGVGALLVSRRGAEVFQKRRFFGGGTINYAYPHAMDYQLRETFHQRYEDGTLPFLSIVGLLEGFRTLERLVPRTDEFSTMERISRHVFGLAKYLEDQLRQLHHPNGEPLVKLYNKVGYQDKSRQGGIVAFNVRTESGSFVGFGEIACVAALHGILLRTGCFCNIGACQYYLGLDEDALDAIYKRAGRICGDYFDLIDGQPTGAVRVSFGYMTTIQDVDKLLQMLRSSYLATK---PLQRIQFIEEQAEQLPPLLKER---------------VQLLRP--------------------------------------------KLLQMAIYPVKSCAAFKIELPGSWPLTDQGLKYDREWMIVDMNGMALTQKRCTELCLIRPVIKVDQ--LELQFGENSTISVPLSLDDQAADTAKCVSKVCRQPVEGLDCGDRVAQWLSENLGMEGLRLLRQSG--QRNSSKDQQ---------KLSLVNQAQFLLLNKSSVRSLQFEEP-------------LDETVDRFRANIIIDTGSAFEELTYKALSIGGIQFQ-----------VEGPCQRCDMICIN-----QRTGERSPETLTTISRLQKGRMRFG-IYITRIPQDTKELEPKEQHMTCGDVVLVE-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . ** *: . .******:**:.:* : .:: .*. *** :.:** * *:.**:::* .*:*:.*** ****:..**** ***: * : . . .* : :.****:*:* : .: : .. : . . . *: :.**.**** : .*. :. :: * ..::: ****.:*: *****. : .*:: :****:** ***:***** .. * :::* :***** : : .. .*:****:.**.::.* .** .*::*. * .*. *.* * :: * * : ** :.::* . :.. ** *: *.: * :*:.:: :*:*..* :******* **** :*.:.:: : : **::*** .*::**:***::*:*****::::* : :*::: : . : : :: . . : :: ::*:****:*:: **: *** *** **:*: **:.::**: ..****:* : : : :: ..* ***. . : :: *:** : *. ***:.:: *** * :*::* *: *****:**:**:* :*: *: .: *****:: . .* * :. ::**. :** : . :: :: .:. : . . : : : . ", "identical_positions": 218, "similar_positions": 238, "identity": "23.22%" }, { "cls_id": "homologset.agr.FB:FBgn0002673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48966-1", "uniprot_id": "MPIP2_RAT", "id": "P48966-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPPQKSAPGSALSTARVLGGIQRPRHLSGFGFGSDGLLGSPERAASSSPVTTLTQTMYNLAGLGSETPKTQVGSLSFQN--RLTDLSLSRRTSECSLSSESSESSDAGLCMDSPSPMDPQTAERTFEQAIQAASRVIQKMQFTIKAS-VFASEAAGHSPVLQ-NITNSQALDSWEKDEAGYRAAS-SPGEDKENDGYIFKMPQKLPHSSSARALAEWASRREAFTQRPSSAPDLMCLTTDGK-MDVEEASPVAQ-SSSLTPVERACEEDDGFVDILES-DLKDDDMVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSPSMPCSV---IRPILKRLERPHDRDVPVLSKRRKSG--TPLEEQQ-LEEPKARVFRSKSLCH----EIESILDSDHRGLIGDYSKAFLLQTVDG--KHQDLKYISPETMVALLTGKFSNIVEK---FVIVDCRYPYEYEGGHIKNAVNLPLEPDAETFLLKHPITPCNL-------------------DKRIILIFHCEFSSERGPRMCRFIRERDR--AANDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHAA----FRDELRNFRLKTRSW---------------------AGERSTTQLCSRLQDQ------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30306-1", "uniprot_id": "MPIP2_MOUSE", "id": "P30306-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPLQKSAPGSALSPARVLGGIQRPRHLSVFEFESDGFLGSPEPTASSSPVTTLTQTMHNLAGLGSEPPKAQVGSLSFQN--RLADLSLSRRTSECSLSSESSESSDAGLCMDSPSPVDPQMAERTFEQAIQAASRVIQNEQFTIKRFRSLPVRLLEHSPVLQ-SITNSRALDSWRKTEAGYRAAANSPGEDKENDGYIFKMPQELPHSSSAQALAEWVSRRQAFTQRPSSAPDLMCLTTEWK-MEVEELSPVAQ-SSSLTPVERASEEDDGFVDILES-DLKDDEKVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSPSMPCSV---IRPILKRLERPQDRDVPVQSKRRKSV--TPLEEQQ-LEEPKARVFRSKSLCH----EIENILDSDHRGLIGDYSKAFLLQTVDG--KHQDLKYISPETMVALLTGKFSNIVEK---FVIVDCRYPYEYEGGHIKNAVNLPLERDAETFLLQRPIMPCSL-------------------DKRIILIFHCEFSSERGPRMCRFIRERDR--AANDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEA----FRDELRNFRLKTRSW---------------------AGERSRRELCSRLQDQ------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30305-1", "uniprot_id": "MPIP2_HUMAN", "id": "P30305-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLR-NITNSQAPDGRRKSEAGSGAAS-SSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRK-MEVEELSPLALGRFSLTPAEGDTEEDDGFVDILES-DLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSV---IRPILKRLERPQDRDTPVQNKRRRSV--TPPEEQQEAEEPKARVLRSKSLCHD---EIENLLDSDHRELIGDYSKAFLLQTVDG--KHQDLKYISPETMVALLTGKFSNIVDK---FVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSL-------------------DKRVILIFHCEFSSERGPRMCRFIRERDR--AVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEA----FKDELKTFRLKTRSW---------------------AGERSRRELCSRLQDQ------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48964-1", "uniprot_id": "MPIP1_MOUSE", "id": "P48964-1", "name": "M-phase inducer phosphatase 1", "aln": "MELGPEPPHRRRLFFACSPT---PAPQPTGKMLFGAS-------AAGGLSPVTNLTVTMDQLEGLGSDCEK------------------MEVRNNSSLQRMGSSESTDSGFCLDSPGPLDSK-----------------ENLEISLTRINSLPQKLLGCSPALKRSHSDSLDHDTFHLIDQ---------DENKENEAFEFKKPIRPASR-----HIYEESK-DPFTHRQNSAPARMLSSNES---ESGNFSPLFIPQSPVK--ATLSDEDDGFIDLLDGENMKNDEETPSCMASLWTAPLVMRRPANLAD------RCG-LFDSPSPCGSS---TRAVLKRADRSHEEPPRG-TKRRKSVPSPVKAKADVPEPAQLP-SQSLSLMSSPKGTIENILDSDPRDLIGDFSKGYLFNTVSG--KHQDLKYISPEIMASVLNGKFAGLIKE---FVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKNPIVPTD--------------------GKRVIVVFHCEFSSERGPRMCRYVRERDR--LGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHED----FKEDLKKFRTKSRTW---------------------AGEKSKREMYSRLKKL------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48965-1", "uniprot_id": "MPIP1_RAT", "id": "P48965-1", "name": "M-phase inducer phosphatase 1", "aln": "MELGPEPPHRRRLLFTCSPT---PAPQPTGKVQFGAS-------RAGGLSPVTNLTVTMDQLEGLGSDYEKP-----------------MDVRNSSSLQRMGSSESTDSGFCLDSPGPLDSK-----------------ENLEISLRRINCLPQKLLGCSPALKRSHSDSLDHDIFQLIDQ---------DENKENEAFEFKKPIRPASRGCLNAHVHEESK-DPFTHRQNSAPARMLSSNESDISESGNFSPLFTPQSPVK--ASLSDEDDGFIDLLDGENLKNDEETPSCMSSLWTAPLVMRRPTNLAD------RCG-LFDSPSPCSSTSSCSTRAVKRADRSHEESPRG-TKRRKSS-EASPVKADVPEPTQLP-HQSLSLTSFPKGTIENIFHSDPRDLIGDFSKGYLFHTVSG--KHQDLKYISPEIMASVLNGKFANLIKE---FVIIDCRYPYEYEGGHIKGAVNLHMEEEVEEFLLKKPIVPAD--------------------GKRVIVVFHCEFSSERGPRMCRYVRERDR--LGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHED----FKEDLKKFRTKSRTW---------------------AGEKSKREMYSRLKKL------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30304-1", "uniprot_id": "MPIP1_HUMAN", "id": "P30304-1", "name": "M-phase inducer phosphatase 1", "aln": "MELGPEPPHRRRLLFACSPP---PASQPVVKALFGAS-------AAGGLSPVTNLTVTMDQLQGLGSDYEQP-----------------LEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSK-----------------ENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDP---------DENKENEAFEFKKPVRPVSRGCLHSHGLQEGK-DLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVT--ATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMR-TTNLDN------RCK-LFDSPSLCSSS---TRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAG--KHQDLKYISPEIMASVLNGKFANLIKE---FVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTD--------------------GKRVIVVFHCEFSSERGPRMCRYVRERDR--LGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHED----FKEDLKKFRTKSRTW---------------------AGEKSKREMYSRLKKL------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48967-1", "uniprot_id": "MPIP3_MOUSE", "id": "P48967-1", "name": "M-phase inducer phosphatase 3", "aln": "MSTGPIPPASEEGSFVSAPSFRSKQRKILHLLLERNTSFTIRSDFPESPKDKLHDSANLSILSGGTPKCCLDLS---------------NLSSGEMSASPLTTSADLEDNGSLDSSGPLDRQ-----------------------LTGKDFHQDLMKGIPVQLLCSTPNAMNHG------------------HRKKIAKRSTSAHKENINTSLKALEWEAPRTPRFRKMPGGPLTSPLCELE--------MKHLGSPITTVPKLSQNVKLEDQERISEDPMECSLGDQDAKGLSLRKMVPLCDMNAIQMEE--------------------------------EESGSELLIGDFS-----------------------------------------------------KVCVLPTVPG--KHPDLKYISPDTVAALLSGKFQSVIER---FYIIDCRYPYEYLGGHILGALNLHSQKELHEFFLRKPVVPLDI-------------------QKRVIIVFLCEFSSERGPRMCRSLREKDR--ALNQYPALYYPELYILKGGYRDFFPEYMELCDPQSYCPMLHQD----HQAELLSWRSQSKAQ---------------------EGERQLQGQIALLVKGASPQ--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LL59-1", "uniprot_id": "A0ABK0LL59_RAT", "id": "A0ABK0LL59-1", "name": "M-phase inducer phosphatase", "aln": "MSTVPFPAASEEGSYVSAPSFRFKQRKMLHLLLERHASFTVGSDFPESPGDKLHDSANLSLLSGGTPKCCLDLS---------------SLSNGEVSASHLSTSADIEENGSLDSSGPQDIH-----------------------LTGKDFHQDLMKGIPAQLLCSTPNALDHG------------------HRRKDAKCSTSANKENINTSFKTLEWEAPRTPRLQKKPGDPLASPLCELENGILLESEMKNLGSPITTVPKLSKNLKLEDQEGISEDPMECSLEDQDAKGLSLKKTVPLCGMDAIELEE--------------------------------EDSDSEHLTGDFSKIVFR---------------------------------NSGSFCINRPAARIVEACVLPTVPG--KHQDLKYISPDTVAALLSGKFQSVIER---FYIIDCRYPYEYLGGHILGALNLYSQKELYEFFLKKPVVPEDT-------------------QKRVIIVFLCEFSSERGPRMCRSLREKDR--ALNQYPALYYPELYILRGGYRDFFPEYMELCEPQGYCPMLHQD----HQAELLSWRSQSKAQ---------------------EGERQLREQIALLVKNVSPQ--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03019-1", "uniprot_id": "TWINE_DROME", "id": "Q03019-1", "name": "Cdc25-like protein phosphatase twine", "aln": "MASKRLMLDVEEEDDESGACGQENFDPHDADMEYQAK-------RRKSAVQETPLQWMLKRHIPASTTVLSPIT----------------ELSQNMNGARLDGTPKSTQRIPANRT-----------------------------LNNFNSLSSRTLGSFSSSCSSYESGNSLD------------------DEYMDMFEMESAEN------------------HNLELPDDLEVLLSGQLKSE----SNLEEMSNKKGSLRRCLSMYPSEQPEEAVQEPDQETNMPMKKMQRKTLSMNDAEIMRALGDEP-------------------------------------------------------------------------------------------ELIGDLSKPCTLPCLATGIRHRDLKTISSDTLARLIQGEFDEQLGSQGGYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF---PTLTSNQ-------------------ENRRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPELYILHNGYKEFFGLYSQLCQPSQYVPMLAPA----HNDEFRYFRAKTKSWQCGEGGDSGIGG---------GGSRGLRKSRSRLLYAE-----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6Z595-1", "uniprot_id": "A0A8M6Z595_DANRE", "id": "A0A8M6Z595-1", "name": "protein-tyrosine-phosphatase", "aln": "MAGDALEICDLT---------------------------------AEDSSPVNELSFRLQNLQCQDGLSPKR-------------------STPRKLVLTPECMSSSLNTLSREKETPTVRR-----------------------RRASRSLSPESTSNTPRCPLRNNQDFPAN-------------------KENERAIKRLRVR------------------LSSRFSSSNATETAGRNRRQ--------------------YRSDPEEDATPSRETEAVDPMAAVRFRQLMSQLQAPPTPVTQVAVAD------------------------------------------------------------------------------------------LTLIGDFSKQHLLPVESAG--HQEHHCISAQTVASLIRGQFGSAVED---FLIVDCRYPYEYQGGHIKGAVNLYTEHQVQQVLHQASAQVSVSTSRLCGRSASDSLPEDEESPSRKLIIFHCEFSSERGPHLCQYLRRLDR--CVNVYPSLHYPELYLLLGGYKHFHASYPDLCDPCGYVSMRQRE----YREQLNSFLRRRQTR-----------------------QRRRRPIRRHHRTKR-----------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23748-1", "uniprot_id": "MPIP_YEAST", "id": "P23748-1", "name": "M-phase inducer phosphatase", "aln": "MNNIFHGTEDECANEDVLSFQKISLKSPFGKKKNIFRNVQTFFKSKSKHSNVDDDLINKENLAFDKSPLLTN-------------------HRSKEIDGPSPNIKQLGHRDELDENENENDD-----------------------IVLSMHFASQTLQSPTRNSSRRSLTNNRD------------------NDLLSRIKYPGSPQ---------------RSSSFSRSRSLSRKPSMNSSSNS--------------------SRRVQRQDGKIPRSSRKSSQKFSNITQNTLNFTSASSSPLAPNSVGVK------------------------------------------------------------------------------------------CFESCLAKTQIPYYYDDRNSNDFFPRISPETLKNILQNNMCESFYN--SCRIIDCRFEYEYTGGHIINSVNIHSRDELEYEFIHKVLHSDTSNN----------------NTLPTLLIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILDGGYKAVFDNFPELCYPRQYVGMNSQENLLNCEQEMDKFRRESKRFATKNNSFRKLASPSNPNFFYRDSHQSSTTMASSALSFRFEPPPKLSLNHRRVSSGSSLNSSESTGDENFFPILSKSSMSSNSNLSTSHMLLMDGLDTPSYFSFEDERGNHQQVSGDEEQDGDFTFVGSDREDLPRPARRSLFPSLETEDKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . . . . :: : : **.: : :: .:: . *:***: **: **** : *: . : : : :: *****.*** : :* ** . ** * **:: :* .**: .. . * * * * . :: : . : : ", "identical_positions": 37, "similar_positions": 49, "identity": "4.89%" }, { "cls_id": "homologset.agr.FB:FBgn0002707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT95-1", "uniprot_id": "D3ZT95_RAT", "id": "D3ZT95-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MERGLPGERQSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVKKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDVLNACLKELKYHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLSKKTKTSEKMAGPEEQETKKELVLESNPKWEALTEVL-KEIETENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPKDAQNKERASTKRGALKRKKKRELTLTQVLGTAEEPPEEGAVEEDLHKQTGSS-------PEVCGGEI----------QHESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFFVYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GTAAMDTPTDTRKAGGQE--RNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFVQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVQNIAELATLSLERLTGILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZD4-1", "uniprot_id": "XPF_MOUSE", "id": "Q9QZD4-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MEPGLSGERRSMAP--------------------------------LLEYERQQVLELLDSDGLVVCARGLGTDRLLYHFLRLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPAMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----VFGQNSGWLFLDASTSMFVNARARVYRVPDVKLNKKAKTSEKTSSPEVQETKKELVLESNPKWEALTDVL-KEIEAENKESEALGGPGRVLICASDDRTCCQLRDYLSAGAETFLLRLYRKTFEKDGKAEEVWVNVRKGDGPKRTTKSDKRPKAAPNKERASAKRGAPLKRKKQELTLTQVLGSAEEPPEDKALEEDLCRQTSSS-------PEGCGVEI----------KRESFDLNVSSDAAYGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLAR--GSAALDAPTDTRKAGGQE--QNGTQSSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFFQEMSSS--------------DVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSE------TLPE-SDRYNPGPQDFVLKMPGVNAKNCRSLMNQVKNIAELATLSLERLTTILGHSGNAKQLHDFLHTAYADLVSKGRVRK-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92889-1", "uniprot_id": "XPF_HUMAN", "id": "Q92889-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------------------MESGQPARRIAMAP--------------------------------LLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPA--------CLVLVLNTQPAEEEYFINQLKIEGVEHLPR---------------------RVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQH----KPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEK----AFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVL-KEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKK-KKRKLTLTQMVGKPEELEEEGDVEEGYRREISSS-------PESCPEEI----------KHEEFDVNLSSDAAFGILKEPLTIIHPLLG-CSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVR--GTASADVSTDTRKAGGQE--QNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSN--------------DISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSE------TLPE-SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDFIHTSFAEVVSKGKGKK-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U361-1", "uniprot_id": "A0AB32U361_DANRE", "id": "A0AB32U361-1", "name": "DNA repair endonuclease XPF", "aln": "-------------------------------------------------------MASA--------------------------------LLEYETEMFLSVFSTDGLLITAEGLGIDRLLLHFMKVYSEEG--------SLVLLLNTSTPEQEYLTERLRAEGVTHLPQ---------------------TVTSDVQSADRYNVYTKGGVLFVTSRILVVDFLTDRIPAHLVTGILVYRAHNIIESCQEAFILRLYRQKNKTGFIKAFTDKATSFSSGFCKVERVMRNLFVKKLFLWPRFQASVNATLDKH----KPDVVELHVTLTPAMRAIQSSILDIMNACLKELKRYNPTLEAEDLSLENSLGTAFEKTIRHYLDPLWHQLGSRTKSLVQDLKILRTLLLYLTQYDCVTFLNLLESLRTSQK----SFGSNSGWLFLDSSMSMFVNARSRVYRIQESK--KKLKVGETEQKQNLAPPKRELVLEKNPKWEALTEVL-QEIEKENSKSEHE--PGRVLICASDDRTCAQLKEYIQKGPEHLLNRLYSRTIGKE-DPQPDLLKLDKGWQKKDSARS-KGKNSRQKRTKANSKK-------------PAKMEKLSRVSQDDSADKDLN-ENSED-------EGGLIEEE----------EEEEIVLDLSSDDYYGILKEPLTVIHPLKG-CSDPYSLTRVLHEVDPMFVVLYDAELSFVRQLEIYKACR---PGKPLRVYFLIYGGSTEEQRYLTALNKEKQAFEHLIREKASMVVPEEREGREDTNLDLVR--SQEPASAATNTRKAGGLE--EVKEPHRIIVDMREFRSELPSLLHRRGLDIEPVTLEVGDYILTSDICVERKSVSDLIGSLQSGRLYTQCLSMTRFYRRPVLLIEFDPAKPFSLVARSDFRQEISAN--------------DVTSKLTLLTLHFPRLRLLWCPSPYVTAELFQELKHGRTEPDASTAQAVTAESE------TVTESADLYNPGPYDFLLRMPGVNVKNVKSLIKHVSCLADLVTFSQETLSEILGSSSNARMLYEFIHNP-MDVRPIQKNK------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24087-1", "uniprot_id": "XPF_DROME", "id": "Q24087-1", "name": "DNA repair endonuclease XPF", "aln": "---------------------------------MADSCAENAAKGTENERPKEVEASADTVPQVEEGVEEYLKRKNMV-------------LLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSG--------NLVLVINSSDWEEQYYKSKIEPKYVHEVAS---------------------TAT------ERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPW----KIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEY----ALS-NSGWTLLDAAEQIFKLSRQRVFNG-----------------------QQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQPKVLILCQDARTCHQLKQYLTQGGPRFLL---QQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPVEVGPAAIDIKPDPDVSIFET----------IPELEQFDVTAALAS-VPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMAN------------ADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDEP------TAGE-QLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKLLYDILHVAHLPEKDEVTGSTALLAASKQFGAGSHNRFRMAAAASRRGRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06777-1", "uniprot_id": "RAD1_YEAST", "id": "P06777-1", "name": "DNA repair protein RAD1", "aln": "MSQLFYQGDSDDELQEELTRQTTQASQSSKIKNEDEPDDSNHLNEVENEDSKVLDDDAVLYPLIPNEPDDIETSKPNINDIRPVDIQLTLPLPFQQKVVENSLITEDALIIMGKGLGLLDIVANLLHVLATPTSINGQLKRALVLVLNAKPIDNVRIKEALEELSWFSNTGKDDDDTAVESDDELFERPFNVVTADSLSIEKRRKLYISGGILSITSRILIVDLLSGIVHPNRVTGMLVLNADSLRHNSNESFILEIYRSKNTWGFIKAFSEAPETFVMEFSPLRTKMKELRLKNVLLWPRFRVEVSSCLNATNKTSHNKVIEVKVSLTNSMSQIQFGLMECLKKCIAELSRKNPELALDWWNMENVLDINFIRSIDSVMVPNWHRISYESKQLVKDIRFLRHLLKMLVTSDAVDFFGEIQLSLDANKPSVSRKYSESPWLLVDEAQLVISYAKKRIFYKNEYTLEENPKWEQLIHILHDISHERMTNHLQGPTLVACSDNLTCLELAKVLNASNKKRGVRQVLLNKLKWYRKQREETKKLVKEVQSQDTFPENATLNVSSTFSKEQVTTKRRRTRGASQVAAVEKLRNAGTNVDMEVVFEDHKLSEEIKKGSGDDLDDGQEENAANDSKIFEIQEQENEILIDDGDAEFDNGELEYVGDLPQHITTHFNKDLWAEHCNEYEYVDRQDEILISTFKSLNDNCSLQEMMPSYIIMFEPDISFIRQIEVYKAIVK---DLQPKVYFMYYGESIEEQSHLTAIKREKDAFTKLIRENANLSHHFETNEDLSHYKNLAERKLKLSKLRKSNTRNAGGQQGFHNLTQDVVIVDTREFNASLPGLLYRYGIRVIPCMLTVGDYVITPDICLERKSISDLIGSLQNNRLANQCKKMLKYYAYPTLLIEFDEGQSFSLEPFSERRNYKNKDISTVHPISSKLSQDEIQLKLAKLVLRFPTLKIIWSSSPLQTVNIILELKLGREQPDPSNAVILGTNKVRSDFNSTAKGLKDGDNESKFKRLLNVPGVSKIDYFNLRKKIKSFNKLQKLSWNEINELINDEDLTDRIYYFLRTEKEEQEQESTDENLESPGKTTDDNALHDHHNDVPEAPV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : .:. *.*:: ..**. :: ::: . ***::*:. :: . :. . .: .* .:* .**: ::***:**:*. : . ::*::* .*. : ...:*:* *.::*.**. **:***:. . :* :. :. *::* :::: :****: * : *: : . :*::*.:: : ** ::: :: : *:. * : : .:** : * : : : **::. .:* :* *:::** *: *.* :: :: :* * ::* : :: :: *:: :: *. : :: * . .: : :: . * .: . : : . . : . . . :. : : .: : . : . *.:: * :::::: ::: :**:*::.* :***: :. : *** :**::.:** ** :* ::.: : . * . . :.:*:*** ::** ***.:.** *::: *: : * : :***::*.::*:****:*******:..** .** * :.* * ****** :.* * : . :: ** *.*:** *:::*..** *.::: *** .: :**. .* : ::. * * . . :*.:*** : .* .: : .* * . : :: : :: ::: ", "identical_positions": 159, "similar_positions": 273, "identity": "14.36%" }, { "cls_id": "homologset.agr.FB:FBgn0002709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI14-1", "uniprot_id": "MCMD2_RAT", "id": "Q5XI14-1", "name": "Minichromosome maintenance domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKLPMKEAALVYLDR------SGGLQKFMDDCKYYNDSKQSYAVYRFSILINPCDVVELDAELGNHILHHPLKAAQVFQSVCFVAVKTLSLIGKL--------QTETQINIVLKLTHLPSLPSYSLDLCEFPLNYASQRFYMMQG-----------------------------------IVIAMTTVTKYTQGARFLCSDEVCPFSKGFQYIRVHVPGATESAT--VRNDFLCRLCSSSLQED--RKFRVLGDKQIIEIIT-----------TKVLHAFQGDPK-------NQPFRFQSLSVFLRDELVN-KMKIGNEYKIIGIPVCVKTSQT-----ALCVEANS---ITPYTAKVPSGISDN--FRCLLSLTSSSCWRFTAILANVFASHIVPLGTYNLLKLCLLMS--------LVQTRDCSSERENCLDILVITSDTLLVDR-LLNFSMN---LVSRGIRHPVCTEVFPTVSRDKYGTGAVSIQAGSALLARGG-------VCFIG-------------DLTSHKKDKLEQLQSALESRSVTVFIPGKKFGDDFD--QQMTFPIQCSFWSFVDMDSSSRRN---------------------VQKASTLIGQMDCSLIPAN--LAEAFGLLVN-----------------------------CKESSPCHPLLPTVQHTLKKAVDPKGPPYLAS----------------------------------------------KQFTTEDFEKLLAFAKNLNVEFSLEAERMIHGYYLASRRIRTDSIHGSKLSANALKYLVSLSEAHARLNLRNKVLREDVLIAALLFEISLTLKYGATAFCVAPNALFPFELYDEDYLEQRDLYLTQCQQQLQHFIATCGPGTAVLSSDE----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q956-1", "uniprot_id": "MCMD2_MOUSE", "id": "E9Q956-1", "name": "Minichromosome maintenance domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METLQMKEAALVYLDR------SGGLQKFIDDCKSYNDSKQSYAVYRFSILIDPCDVVELDADLGNHILHHPLKAARVFQSVCFVAVKTLSLIGQL--------QTETQINIVLKLTHLPALPSYTLDLCEFPLNYASQRFYMMQG-----------------------------------IVIAMTTITKYTQGARFLCSDGVCPLSKGFQYVRVHVPGATESAT--VRNDFLCSLCSSSLQED--RKFRVLGDKQIVEIIT-----------TKMFHAFQGDSK-------NQPFRFQSLGIFLRDELVN-KMKIGNEYKIIGIPVCVKTSQT-----ALCVEANN---ITPHTAKVPLGISDN--FRRLLSLTSSSCWKFTAMLANVFASQIVAPGTYNLLKLCLLMS--------LVQTRDCNREREDCLDILVITSDTLLVDR-LLNFSMN---LVSRGIRHPVCTEVFPTVSRNKYGTGAVSIQAGSALLAKGG-------ICFIG-------------DLTSHKKDKLEQLQSALESRSVTVFIPGKKFGDDFD--QQMTFPIQCSFWSFVDMDSSSRRN---------------------VQKTSTLIGQMDCSLIPAN--LAEAFGLLIN-----------------------------CSEASPCHPLLPTVQHTLKKAVEPEGLLYLAS----------------------------------------------KQFTTEDFEKLLAFAKSLNMEFSLEAERMIHGYYLASRRIRTDSIHGSKLSASALKYLVSLSEAHARLSLRTTVLREDALIAALLLEISLTLRYGATPFCVAPNALFPFELYNEEYLEQRDLYLTQCQQQLQQFIATCGPGTTVFSSDE----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0Z9-1", "uniprot_id": "MCMD2_HUMAN", "id": "Q4G0Z9-1", "name": "Minichromosome maintenance domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNLKMKEAALIYLDR------SGGLQKFIDDCKYYNDSKQSYAVYRFKILINPSDVVELDAELGNHILHQPLKAAEVFQSVCFIAVKTLSLIGQL--------QTETQINIVLKLTHLPPLPSYGLDLCEFPLDYTSQRFYMMQG-----------------------------------IVIAMTTITKYTQGARFLCSDEACPLSKGFQYIRVHVPGATESAT--IRNDFLCNLCASSLQED--RKFRVLGDKQIVEIIA-----------TKALRAFQGYSN-------NQPFRFQSLTIFLRDESVN-KMNIGNEYKIIGIPTCVKTSQT-----AVCIEANS---ITFCNSKVPSGISDN--FRCLLSLTSSSCWKFTAILANIFASQITPPGTYNLLKLCLLMS--------LVQTTDRNKELEDCLDILIITSDTLLIDR-LLNFSIN---LVPRGIRHLVSTEIFPTLSRNKYGTGAVSIQAGSALLAKGG-------ICFIG-------------DLASHKKDKLEQLQTVLESRSITVYIPGKKFGEDID--QQMTFPVQCSFWSFVDVDSSSRRN---------------------AQKINTLIGQMDCSLIPAN--LVEAFGLLIN-----------------------------CNESSPCHPFLPTVQHTLNKAINPEGLFYAAS----------------------------------------------RQFTTEDFEKLLAFAKNLNVEFSLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLSEAHARLNLRNKVLKEDVLIAALLFETSLTLKYGATVFCVAPNAVFPFELYNEEYLEQRDLYLTQCQQQLEQFIATYGPGTTIFSSDE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHR4-1", "uniprot_id": "Q0KHR4_DROME", "id": "Q0KHR4-1", "name": "", "aln": "MSSTNKLEKKDPRRHIPLQLNVFLRNDDDGEVREVTQNANTSSIGTIPSNGLVESDVTPIMTPTPKAGVYKPNVNVWRLSKEVTKPDRSFVVSAEEYPDLGQRPKRFKQRTPRVRNQDDGGTVSCLASRFSRVKDPPVLGNFLPDFMLPKSSNSNHQSVTTWLSSVRPSDSQKSLSDQARCSSSTNITLLSKDSVQPLTPKSSAQSSPGEKNIQQEQNTPAKSQQEETSPANSVEHQQKTPNSPKEQQKSSVGFTNMQQMASANSLQQQNSSASSLQQQNSSVHSLQKRKSWVNSSQQQRSSVNFIQKQRSWVNSSHHQKSSASSLQQKSSENSPSKFQQQQQKSPANNERSQNNQKSPGIQHSWKQQQQQKPKILQNCPKTSVQQQMNPVNHTQSQSERPTELIYLHSRSPAKRASVTNNSSAPIRIAPRQQTTQSSGPSVVHNEDEDVMPPTPNQSERRQRRFPRRNHNPRMVRSLQAVSREFTESLLEGSSGKTPEKEVVPYQQQEKPRQVKSSPEIHASSHMRKLAMGSVLNSNAKEFHPTGESHLTHKVSRLSQRRCRQRFTRSLHAKKNNPREQLPNPDSAPEPILEYTSEIDDQPCPPRQTVDTPIEAIVPPAMIEVSATGNLPPVFYFDQQSGIIWSNSSPQIPVEIQSNSVSQSVFRLASLPCTGVGTTNMDIFTSSPPPIQHMSSSRLPSSISGPTQLSHTLSSPPVENQHQQHLWESCIHQDEDLMYSRPLLDMDQEETQPEQQDQEWQWESEIEPPSFQSENQVVADEHGEENAYLAKDAGPPLERHMIFRAPSQHGQEYPKPDLNCVPSSIKKLHHLISSQYSDYSFVYALSAQISQDCVPMDCFVYLKMILLASIVSIESDEVRAPISLCIIATDSLMANRLLNKVGQLAPRFLGPHEYGLQPTFNALPTRFNWIVASPLLLAQQGVYYAGDWNRLSKDQGCQLEKCIENGAVPVPQLHIDQPLKAAVWTYWQPNNSTNQTLALAKLCPIFGLPIYMGAQASNSLWNSIIQKHNAEGQIVVNDGLSIPEDDMRMLIHLLHQRKTTLTDGAQHMLQKYYVISRKERPN-----VFSSKTYIVLKQLAECFAKLALRLEVLESDVCVAIFHCEHFVQGIFGAKENQAPP------AVFNFNVISCIDPYMNKFTRWLLQYLNSYEDEELGMHADKRRRTDSWDMP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.::: :::: *. ** .. :.*::* : :: . .*.: . : : . :::. * . :. : . *: :: *:* ::: :: *. : : .. *: :.:: .. :* :: :::: : : *. * .: . * : . * .:*:. ...: *. .*: :. ::*: *:.:: . :: *: ::* :. .. . * : . : *: : .:.. : * *. ::.* * .. .: :. : ..::* *..* : :: *:* .* . : ::*:* . . :* :* * .. . . :. : : .: *: .* **::. : :. . :*: *. :.: . * . .* **:.. : * . : .. . .**.:* : * *: . ::.:* : :.: : *:*.::*.. * * ::* : .* *: * *. :: * * .. :::.*: *: . :: .:. :*:. *: : :. : :: *::* : **: **: *.. :*:.: * *:*..*:* ** **..*. :* : * : :**. ..* ::: : :. * *:.: : * ::: : : :*: ", "identical_positions": 101, "similar_positions": 278, "identity": "8.44%" }, { "cls_id": "homologset.agr.FB:FBgn0002716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8A8-1", "uniprot_id": "D3Z8A8_RAT", "id": "D3Z8A8-1", "name": "Meiotic recombination protein SPO11", "aln": "MALAPMGPEASFFDALDRHRASLLAMVKKGAGETPDRATRVPSSSEVLTSIENIIQDIIKSLARNEAPAFTIDNRSSWENMTFEDAFGLQMRPQCTTRKIKSDSLRSVRKFALILKILSMIYKLIQSNTYATKRDIYYTESQLFRNQAAVDSIIDDISCMLKVPRR-SLHVISTSKGLIAG--------NLRYVEEDGTQVQCMCSATATAVP---SNIQGMQNLVTDAKFLLIVEKDATFQRLLDDNFCSRMSP-CIMVTGKGTPDLNTRLLVKKLWD---TFHIPVFTLVDADPYGIEIMCIYKYGSMSMSFEAHNLTVPTIRWLGLLPSDIKRLNIPKDSLIPLTRRDQMKLDSILRRPYITYHPFWKKEMEMLADSKTKAEIQALSFLSSDYLSRVYLPNKLRFGGWI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTK8-1", "uniprot_id": "SPO11_MOUSE", "id": "Q9WTK8-1", "name": "Meiotic recombination protein SPO11", "aln": "MAFAPMGPEASFFDALDRHRASLLAMVKRGAGETPAGATRVASSSEVLTAIENIIQDIIKSLARNEVPAFTIDNRSSWENIMFDDSVGLRMIPQCTTRKIRSDSPKSVKKFALILKVLSMIYKLIQSDTYATKRDIYYTDSQLFGNQAAVDSAIDDISCMLKVPRR-SLHVLSTSKGLIAG--------NLRYMEEDGTRVQCTCSATATAVP---TNIQGMQHLITDAKFLLIVEKDATFQRLLDDNFCSRMSP-CIMVTGKGVPDLNTRLLVKKLWD---TFHIPVFTLVDADPYGIEIMCIYKYGSMSMSFEAHNLTIPTIRWLGLLPSDIQRLNIPKDSLIPLTKHDQMKLDSILKRPYITYQPLWKKELEMMADSKMKAEIQALTLLSSDYLSRVYLPNKLRFGGWI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5K1-1", "uniprot_id": "SPO11_HUMAN", "id": "Q9Y5K1-1", "name": "Meiotic recombination protein SPO11", "aln": "MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRR-SLHILSTSKGLIAG--------NLRYIEEDGTKVNCTCGATAVAVP---SNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSP-CIMITGKGVPDLNTRLLVKKLWD---TFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KPA5-1", "uniprot_id": "SPO11_DROME", "id": "Q7KPA5-1", "name": "Meiotic recombination protein W68", "aln": "-------------------------------------------MDEFSENIERIALELLSNLVHGNATLSVPRNSS--------------GNVISEYRRVSYNNRGSRHSFCVLIYMLSRVHRLQVRGGSFTVRGLYYDNPLLVRSQSRIAEARLDVCRMLRTSPL-SLGILAASKGLVAG--------DLRLLMTNGDVLDSSLYGGPLTLP---TDPEKIDRIETLAEFVLIVEKESVFESLLSRNVFGTFERRFILITGKGYPDCCTRRIVHRLTE---ENQLAAYILVDADPFGVEIMLVYRHGSKSMSFSSQGLTTPALRWIGLHPSEIPALGTG---AVALVAGDNKKINDLLAR--HDLEPGVRQELRMLQDVQLKAEIESV----IDFLTDDYIPNKINRNLFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23179-1", "uniprot_id": "SPO11_YEAST", "id": "P23179-1", "name": "Meiosis-specific protein SPO11", "aln": "MALEGLRKKYKTRQELVKALTPKRRSIHLNSNGHSNGTP--CSNADVLAHIKHFLSLAANSLEQHQQPISIVFQNKKKKGDTSSPDIHTTLDFPLNGPHLCTHQFK-LKRCAILLNLLKVVMEKLPLGKNTTVRDIFYSNVELFQRQANVVQWLDVIRFNFKLSPRKSLNIIPAQKGLVYSPFPIDIYDNILTCENEPKMQKQTIFPGKPCLIPFFQDDAVIKLGTTSMCNIVIVEKEAVFTKLVNN--YHKLSTNTMLITGKGFPDFLTRLFLKKLEQYCSKLISDCSIFTDADPYGISIALNYTHSNERNAYICTMANYKGIRITQVLAQNNEVHNKS-IQLLSLNQRDYSLAKNLIAS---LTANSWDIATSPLKNVIIECQREIFFQKKAEMNEIDARIFEYK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *:.: ..* : : . : . :: .. : .::: :*. : . . * *.::* : *. *: : . : :: . ** ::.:.***: . :: : . : : : * ::****::.* *:. :. :::**** ** ** ::::* : :.****.*:.* * :.. :: . . :* : ..: . :.* * ..:: : : :.: : . : : . ", "identical_positions": 39, "similar_positions": 103, "identity": "9.47%" }, { "cls_id": "homologset.agr.FB:FBgn0002719", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13697-1", "uniprot_id": "MAOX_RAT", "id": "P13697-1", "name": "NADP-dependent malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MDPRAPRRRHTH------QRGYLLTRDPHLN---------------------------------------------KDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVK------------------------------------------------------AIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEKARQKIWLVDSKGLIVKGR--ASLTEEKEVFAHEHEE-----MKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAEVISQQVSDKH-LEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQILPDCYSWPEEVQKIQTKVNQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06801-1", "uniprot_id": "MAOX_MOUSE", "id": "P06801-1", "name": "NADP-dependent malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRAPRRRHTH------QRGYLLTRDPHLN---------------------------------------------KDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVK------------------------------------------------------AIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGR--ASLTEEKEVFAHEHEE-----MKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTAEVISQQVSDKH-LQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQILPDCYPWPAEVQKIQTKVNQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48163-1", "uniprot_id": "MAOX_HUMAN", "id": "P48163-1", "name": "NADP-dependent malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MEPEAPRRRHTH------QRGYLLTRNPHLN---------------------------------------------KDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIK------------------------------------------------------AIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGR--ASLTQEKEKFAHEHEE-----MKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDKH-LEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K4C6-1", "uniprot_id": "A0A0G2K4C6_RAT", "id": "A0A0G2K4C6-1", "name": "Malic enzyme", "aln": "------------------------------------------------------------------------------------MGAALGTGARLTS--------------------------------------LPR-LACGSLRRQALSAPAQGCHSKSGPPRPVPLK------KRGYDVTRNPHLN---------------------------------------------KGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWPEDNIKLFLQLPTQSSECEEHCLSVIWPLRILAHMPERTSHLQLMNPLASSQTSCFIPYNAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVRGKEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAVRKIWMVDSKGLIVKGR--SHLNHEKEMFAQEHPE-----VNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYQVTEGRGIFASGSPFKSVTLEDGRTFIPGQGNNAYVFPGVALGIIAGGIRHVPDEIFLLTAEQIAQEVSEQH-LSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPEPKDKEAFIKSLIYTPDYDSFSLDTYTWPKEAMSVQKV-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VG31-1", "uniprot_id": "Q9VG31_DROME", "id": "Q9VG31-1", "name": "Malic enzyme", "aln": "MGNSSSICADRNVITNFDENGTPVYPTANNSQSPSSYSRGKERELGCYTKRNSNSNNNNSHERESQSCCSSRVCKNHTTTTTTTLEYELSNFAKLTTRITTQSAAEVDTSPHTDTETHRDRDSNPGNIALATDLELPKGLPLSLSSRHHWNQLQSSLHALHHQQQQQQQQ------LRSYSSTSETNLEDKMSKPDSKLDKYAQRDRLGLWGTGDNEVVGSLSGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVR------------------------------------------------------AIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTEHKLHFAQLHEP-----IDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNN-KKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDD-LAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMYDLDYPRSVPATYKM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0G2K502-1", "uniprot_id": "A0A0G2K502_RAT", "id": "A0A0G2K502-1", "name": "Malic enzyme", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MKWHLCAGIGRREKMFSRLRAVTTPCTLTCRRVHLK------EKGKPLMLNPRTN---------------------------------------------KGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLKKYQEKYCTFNDDIQGTAAVALSGLLAAQRVINKPISEHRILFLGAGEAALGIAKLIVISMMESGLSEEEAQRKIWMFDKNGLLVKGR-TARIDSNQEPYAHAASENI---PATFEDAVNKLKPSVIIGVAGAGPLFTPGVIKAMAAINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVRLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTSQLTDEE-LAQGRLYPSLANIQEVSANIAIKIAEYLYANKMAFRYPEPEDKAKYVKERIWRSNYVSLLPDVYDWPESSLKPPQIPE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KE1-1", "uniprot_id": "MAOM_MOUSE", "id": "Q99KE1-1", "name": "NAD-dependent malic enzyme, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MFSRLRAVTTPCTLTCRRVHLK------EKGKPLMLNPRTN---------------------------------------------KGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIVLSMVESGLSEEEAQRKIWMFDKSGLLVKGR-TASIDSNQEPYAHAAPESI---PATFEDAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQLTDAE-LAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPEPEDKARYVRERIWRSNYVSLLPDVYDWPESSLTPPQITEEKLPH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23368-1", "uniprot_id": "MAOM_HUMAN", "id": "P23368-1", "name": "NAD-dependent malic enzyme, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MLSRLRVVSTTCTLACRHLHIK------EKGKPLMLNPRTN---------------------------------------------KGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVK------------------------------------------------------AVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGR-KAKIDSYQEPFTHSAPESI---PDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEE-LAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36013-1", "uniprot_id": "MAOM_YEAST", "id": "P36013-1", "name": "NAD-dependent malic enzyme, mitochondrial", "aln": "-------------------------------------------------------------------------------MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTRSHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQLLNSPLFN---------------------------------------------KGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVD-----------------------------------------------------YIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPS-AVLHFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSY-EANSTPAQHVYAKSDAEWAGINTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVPADLMKWTNNNALVATGSPFPPV-----DGYRISENNNCYSFPGIGLGAVLSRATTITDKMISAAVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGGAPGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .. : *. *** :** : :..::* . . * : : : : : :*: *:: :: .: ::*::**** * * *. .:...*:*: * : . : : : :**:*.* ***:** * *: *.:.**.* * .*:.* . **: :****:. : .* :*:* * ** ::::*:.* : :::****. ** *:* **: . ********.:*.::.::*: : . :.: .:: ***.*.:***. : : *: : :* :*::.* *:: :. . : ::: .: *. ::*. ::* : . *. ::. * : *:**.***** *. . . *:.. :.*:**** .* .:.** * ***:.*. : : : :: :.. :: . . . * * * .* * :* : . * * :: ", "identical_positions": 121, "similar_positions": 172, "identity": "14.19%" }, { "cls_id": "homologset.agr.FB:FBgn0002733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "---------------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQP---ASVCSTEAP----------GSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSG-----------GPPSLTPAS-------------------------------------------------ASAPAP----------------SPPVP----------------PPSSL-----GLWRPW--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "---------------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQP---ATLYSSAAP----------GPLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSD-----------DSPSLTLPP-------------------------------------------------APAPAP----------------SPPVP----------------PPGSS-----GLWRPW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y543-1", "uniprot_id": "HES2_HUMAN", "id": "Q9Y543-1", "name": "Transcription factor HES-2", "aln": "---------------------MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELP---ASSWPTAAP----------LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGPSAPAPAP-------------------------------------------------ASAPEPA---------------SAPVPSPPS------------PPCGP-----GLWRPW--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HCC6-1", "uniprot_id": "HES4_HUMAN", "id": "Q9HCC6-1", "name": "Transcription factor HES-4", "aln": "MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADP----------AVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAP-------------------------------------------EVYAGRPLLPSLGGPFPLLAP--------PLLPGLTR-------ALPAAPRAGP-QGPGGPWRPWLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14469-1", "uniprot_id": "HES1_HUMAN", "id": "Q14469-1", "name": "Transcription factor HES-1", "aln": "MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDP----------SVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NTZ6-1", "uniprot_id": "A0A8M1NTZ6_DANRE", "id": "A0A8M1NTZ6-1", "name": "", "aln": "------------MDMTATKLQQNSCQLHISSKEERKLRKPLIERKRRERINLCLDQLRETVVAVFKPDQ---SKLEKADILEMTVKHLQNIQSSR----VSDPV-------LNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLLNHLFKSLP---------LSAKDCPRLPKTSLTSVPSDHSEY-------------------------------SSFHVDETASPKPCSSSP----------FLCKRPNQSQNQHFTPIRMPHDVESSHLSV-LQMWRPW--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "--------------MTASNMG-NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQ---SKLEKADVLEITVQHMENLQRGHGQGGSNSPG-------TGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSPTQSPINLPSSL-------------------------------QPHALLLSPSP-PSSPTH----------SLVRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01069-1", "uniprot_id": "ESMB_DROME", "id": "Q01069-1", "name": "Enhancer of split mbeta protein", "aln": "---------------MVLEMEMS------KTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHRLN---------YLQVVVPSLPIGVPLQAP-------------------------------------VEDQAMVTPPPSECDSLE----------SGACSPAPSEASSTSGP----------------MWRPW--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q61657-1", "uniprot_id": "HES3_MOUSE", "id": "Q61657-1", "name": "Transcription factor HES-3", "aln": "-----------------------------------------MEKKRRARINVSLEQLRSLLERHYSHQIRK-RKLEKADILELSVKYMRSLQNSLQGLWPVPSG-------------VDYPSGFQGGLRGVSQRLRPGEGDSGLRCPLLLQRREGSTTDSANPQATSVLNPCLPAIWAPSRAAGG---------------------------------------SHSPQSPLPLPGGLLESS--------TDVVAPHPASN-----------CQAESTRPGFRVWRPW--", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::** *** .* :*: : : :*****:**::*..:.. : *: : . * . *: : * **** ", "identical_positions": 24, "similar_positions": 24, "identity": "8.28%" }, { "cls_id": "homologset.agr.FB:FBgn0002734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1NTZ6-1", "uniprot_id": "A0A8M1NTZ6_DANRE", "id": "A0A8M1NTZ6-1", "name": "", "aln": "--------MDMTATKLQQNSCQLHISSKEERKLRKPLIERKRRERINLCLDQLRETVVAVFKPDQ---SKLEKADILEMTVKHLQNIQSSR----VSDPVLNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLLNHLFKSLP---------LSAKDCPRLPKTSLTSVPSDHSEYSSFHVDETASPKPCSSSPFLCKRPNQSQNQHFTPIRMPHDVESSHLSV-LQMWRPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "----------MTASNMG-NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQ---SKLEKADVLEITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSP-PSSPTHSLVRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "-----------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASV------CSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSG-----------GPPSLTPASASAPAP-SPPVP----PPSSLG----------------------------------------LWRPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "-----------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATL------YSSAAPGPLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSD-----------DSPSLTLPPAPAPAP-SPPVP----PPGSSG----------------------------------------LWRPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y543-1", "uniprot_id": "HES2_HUMAN", "id": "Q9Y543-1", "name": "Transcription factor HES-2", "aln": "-----------------MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPASS------WPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGPG----------------------------------------LWRPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ70-1", "uniprot_id": "A0AB32TZ70_DANRE", "id": "A0AB32TZ70-1", "name": "", "aln": "MTPNIITEAHPHSFGSRMTVAQRK-EAHELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTVRFLRDLPS----------SSAKGQTDSYKEGYKACLQRISTMLPQS-NLETEAHQRVSEFIHTCSS--------------RWRLLHRPARTAVLRTQK---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01071-1", "uniprot_id": "ESMD_DROME", "id": "Q01071-1", "name": "Enhancer of split mdelta protein", "aln": "---------------MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQR-VANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMK---------QEEEIIDMAEEPVNLADQKRSKSPREEDIHHG--------------------------------------EEVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . ** ***:*::** *:* *..*: :: : *******:**:**..:. : : ** . .: :: :: :: : : ", "identical_positions": 25, "similar_positions": 33, "identity": "10.59%" }, { "cls_id": "homologset.agr.FB:FBgn0002735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1NTZ6-1", "uniprot_id": "A0A8M1NTZ6_DANRE", "id": "A0A8M1NTZ6-1", "name": "", "aln": "------------MDMTATKLQQNSCQLHISSKEERKLRKPLIERKRRERINLCLDQLRETVVAVFKPDQSK---LEKADILEMTVKHLQNIQSSR----------------------------------VSDPVLNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLLNHLFKSLP---------LSAKDCPRLP-KTSLTS-------------------------------------------VPSDHSEYSSFHVDETASPKPCSSSPFLCKRPNQSQNQHFTPIRMPHDVESSHLSV-LQMWRPW--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "--------------MTASNMG-NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQSK---LEKADVLEITVQHMENLQRGHGQ------------------------------GGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLP-LSPTQS-------------------------------------------PINLPSSLQPHALLLSPSP-PSSPTHSLVRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K6W4-1", "uniprot_id": "A0A0G2K6W4_RAT", "id": "A0A0G2K6W4-1", "name": "Transcription cofactor HES-6", "aln": "---------MAPPQAPNRDRAGQEDEDRWEARGDRKARKPLVEKKRRARINESLQELR--LLLAGTEVQAK---LENAEVLELTVRRVQGALRGRARGEWRRGSRAGALTGHACHPRAGHVGSRSLGPVHEREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLNHLLESMPLREGSSFRDLLGDSLAGLPGGSGRSS-------------------------------------------WPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVPTSLGILTTARRAQSVWRPW--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "---------------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLR---EQPAS---------------------------------VCSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSGGP------PSLTPASASAPAPSP-----------------------------------------------------------------------------------------PVPPPSSL-----GLWRPW--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "---------------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQ---EQPAT---------------------------------LYSSAAPGPLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSDDS------PSLTLPPAPAPAPSP-----------------------------------------------------------------------------------------PVPPPGSS-----GLWRPW--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCC6-1", "uniprot_id": "HES4_HUMAN", "id": "Q9HCC6-1", "name": "Transcription factor HES-4", "aln": "MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVT---------------------------------AALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSR---RPASLSPAAPAEAPAP-------------------------------------------EVYAGRPLLPSLGGPFPLLAP--------PLLPGLTR-------ALPAAPRAGP-QGPGGPWRPWLR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14469-1", "uniprot_id": "HES1_HUMAN", "id": "Q14469-1", "name": "Transcription factor HES-1", "aln": "MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMT---------------------------------AALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMT---YPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWRN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TGS1-1", "uniprot_id": "HES3_HUMAN", "id": "Q5TGS1-1", "name": "Transcription factor HES-3", "aln": "-----------------------------------------MEKKRRARINVSLEQLKSLLEKHYS-HQIRKRKLEKADILELSVKYMR---SLQNS---------------------------------LQGLWPVPRGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAP--------------------------------------------AAGGPRSPPPLLLLPESLP--------------GSSASVPPPQPASSRCAESPGLGLRVWRPWGSPGDDLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61657-1", "uniprot_id": "HES3_MOUSE", "id": "Q61657-1", "name": "Transcription factor HES-3", "aln": "-----------------------------------------MEKKRRARINVSLEQLRSLLERHYS-HQIRKRKLEKADILELSVKYMR---SLQNS---------------------------------LQGLWPVPSGVDYPSGFQGGLRGVSQRLRPG-EGDSGLRCPLLLQRREGSTTDSANP--QATSVLNPCLPAIWAPSR--------------------------------------------AAGGSHSPQSPLPLPGGLL--------------ESSTDVVAPHPASNCQAESTRPGFRVWRPW--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01070-1", "uniprot_id": "ESMC_DROME", "id": "Q01070-1", "name": "Enhancer of split mgamma protein", "aln": "-------------------MSSLQMSEMSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQHKR-------------------------------ASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQPAEKEVLPVTAPLSVHIANRDAY--------------------------------------------SVPISPISSYAGSPNSNTS---------------STSHSLLTTIDVTKMEDDSEDEENVWRPW--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::** *** .* :*: : : **:*::**::* :. *: : : : : *: . **** ", "identical_positions": 20, "similar_positions": 22, "identity": "6.21%" }, { "cls_id": "homologset.agr.FB:FBgn0002736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0X6-1", "uniprot_id": "F1M0X6_RAT", "id": "F1M0X6-1", "name": "", "aln": "MALASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A72-1", "uniprot_id": "MGN2_HUMAN", "id": "Q96A72-1", "name": "Protein mago nashi homolog 2", "aln": "MAVASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27W02-1", "uniprot_id": "MGN_RAT", "id": "Q27W02-1", "name": "Protein mago nashi homolog", "aln": "--MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61327-1", "uniprot_id": "MGN_MOUSE", "id": "P61327-1", "name": "Protein mago nashi homolog", "aln": "--MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61326-1", "uniprot_id": "MGN_HUMAN", "id": "P61326-1", "name": "Protein mago nashi homolog", "aln": "--MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQL1-1", "uniprot_id": "MGN2_MOUSE", "id": "Q9CQL1-1", "name": "Protein mago nashi homolog 2", "aln": "--MGSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q566Y8-1", "uniprot_id": "MGN_DANRE", "id": "Q566Y8-1", "name": "Protein mago nashi homolog", "aln": "-MSTSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49028-1", "uniprot_id": "MGN_DROME", "id": "P49028-1", "name": "Protein mago nashi", "aln": "-MSTEDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDTMIRKEAFVHQSVMEELKRIIIDSEIMQEDDLPWPPPDRVGRQELEIVIGDEHISFTTSKTGSLVDVNRSKDPEGLRCFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****************************************.******:**:********** **** :*** *************************** ***:***:******** *************************", "identical_positions": 131, "similar_positions": 7, "identity": "88.51%" }, { "cls_id": "homologset.agr.FB:FBgn0002772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09542-1", "uniprot_id": "MYL3_MOUSE", "id": "P09542-1", "name": "Myosin light chain 3", "aln": "MAPKKPEPKKDDAKAAAPKAAPAPAAAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDT---GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG---QEDSNGCINYEAFVKHIMAS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16409-1", "uniprot_id": "MYL3_RAT", "id": "P16409-1", "name": "Myosin light chain 3", "aln": "MAPKKPEPKKDDAKTAAPKAAPAPAAAPAAAP----EPERPKEAEFDASKIKIEFTPEQIEEFKEAFQLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDT---GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG---QEDSNGCINYEAFVKHIMAS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08590-1", "uniprot_id": "MYL3_HUMAN", "id": "P08590-1", "name": "Myosin light chain 3", "aln": "MAPKKPEPKKDDAK-AAPKAAPAPAPPP--------EPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDT---GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG---QEDSNGCINYEAFVKHIMSS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06742-1", "uniprot_id": "MLC1_DROME", "id": "P06742-1", "name": "Myosin alkali light chain 1", "aln": "MADVPKREVEN-----------------------------------------VEFVFEVMGSPGEGIDAVD-------------LGDALRALNLNPTLALIEKLGGTKKR---NEKKIKLDEFLPIYSQVKKEKEQ---GCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFADCMDPEDDEGFIPYSQFVQRLMSDPVVFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53141-1", "uniprot_id": "MLC1_YEAST", "id": "P53141-1", "name": "Myosin light chain 1", "aln": "MSATRAN----------------------------------------------KDIFTLFDKKGQGAIAKDS------------LGDYLRAIGYNPTNQLVQDIIN-ADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKG--VEVDSNGEIDYKKFIEDVLRQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . : : . :. * ** ***:. *** : : . : . : :: : : . .*: : . ***:: ::::*** .*.: .:*:: * *** * : :*: *: . *.:* * *. *:: :: . ", "identical_positions": 31, "similar_positions": 50, "identity": "14.42%" }, { "cls_id": "homologset.agr.FB:FBgn0002773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QVP4-1", "uniprot_id": "MLRA_MOUSE", "id": "Q9QVP4-1", "name": "Myosin regulatory light chain 2, atrial isoform", "aln": "--------------------------------------------------------------------MASRKAGTRGKAAATKQAQRGSSNVFSMFEQAQIQEFKE----------------------------------AFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLAGNIDYKSLCYIIT-HGDEKEE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M7K3-1", "uniprot_id": "F1M7K3_RAT", "id": "F1M7K3-1", "name": "", "aln": "--------------------------------------------------------------------MASRKAGTRGKAAATKQAQRGSSNVFSMFEQAQIQEFKE----------------------------------AFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLTGNIDYKSLCYIIT-HGDEKEE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01449-1", "uniprot_id": "MLRA_HUMAN", "id": "Q01449-1", "name": "Myosin regulatory light chain 2, atrial isoform", "aln": "--------------------------------------------------------------------MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKE----------------------------------AFSCIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQE--------GKGPINFTVFLTLFGEKLNGT---DPEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIIT-HGDEKEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZCI9-1", "uniprot_id": "D3ZCI9_RAT", "id": "D3ZCI9-1", "name": "", "aln": "MKLGSQEPGSARSWAYSSAREVGVSSSPEPGTLSWGLRNSNFWAPRCPVSIPAPGRMLSFFLLTIPSSQAPRRARKR-------VEGTASSNVFSMFDQSQIQEFKE----------------------------------AFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKE--------APGPINFTVFLTMFGEKLKGT---DPEETILHAFKVFDTEGKGFVKADFIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT-HGEEKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62082-1", "uniprot_id": "MYL10_MOUSE", "id": "Q62082-1", "name": "Myosin regulatory light chain 10", "aln": "--MGQ------------SSLDHGVQG-PVAGTGDFGPLK----------EATATG--------FISCAQAPRRARKR-------VEGTASSNVFSMFDQSQIQEFKE----------------------------------AFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKE--------APGPINFTVFLTMFGEKLKGT---DPEETILHAFKVFDTEGKGFVKADFIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT-HGEEKD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUA6-1", "uniprot_id": "MYL10_HUMAN", "id": "Q9BUA6-1", "name": "Myosin regulatory light chain 10", "aln": "-----------------MLLRLVSNSWPQVILPPR--------PPK------------------VLGLQAPRRARKR-------AEGTASSNVFSMFDQSQIQEFKESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKE--------APGPINFTVFLTMFGEKLKGT---DPEETILHAFKVFDTEGKGFVKADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT-HGEEKD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08733-1", "uniprot_id": "MLRV_RAT", "id": "P08733-1", "name": "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform", "aln": "--------------------------------------------------------------------MSPKKAKKR-------LEG-GSSNVFSMFEQTQIQEFKE----------------------------------AFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKE--------APGPINFTVFLTMFGEKLKGA---DPEETILNAFKVFDPEGKGSLKADYVREMLTTQAERFSKEEIDQMFAAFPPDVTGNLDYKNLVHIIT-HGEEKD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51667-1", "uniprot_id": "MLRV_MOUSE", "id": "P51667-1", "name": "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform", "aln": "--------------------------------------------------------------------MAPKKAKKR-------IEG-GSSNVFSMFEQTQIQEFKE----------------------------------AFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKE--------APGPINFTVFLTMFGEKLKGA---DPEETILNAFKVFDPEGKGSLKADYVREMLTTQAERFSKEEIDQMFAAFPPDVTGNLDYKNLVHIIT-HGEEKD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10916-1", "uniprot_id": "MLRV_HUMAN", "id": "P10916-1", "name": "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform", "aln": "--------------------------------------------------------------------MAPKKAKKR-------AGG-ANSNVFSMFEQTQIQEFKE----------------------------------AFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKE--------APGPINFTVFLTMFGEKLKGA---DPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIIT-HGEEKD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O93409-1", "uniprot_id": "MLRSA_DANRE", "id": "O93409-1", "name": "Myosin regulatory light chain 2, skeletal muscle isoform A", "aln": "--------------------------------------------------------------------MAPKKAKRRA------AGGEGSSNVFSMFEQSQIQEYKE----------------------------------AFTIIDQNRDGIISKDDLRDVLASMGQLNVKNEELEAMIKE--------ASGPINFTVFLTMFGEKLKGA---DPEDVIVSAFKVLDPEGTGSIKKEFLEELLTTQCDRFTAEEMKNLWAAFPPDVAGNVDYKNICYVIT-HGEEKEE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q66I73-1", "uniprot_id": "MLRSB_DANRE", "id": "Q66I73-1", "name": "Myosin regulatory light chain 2, skeletal muscle isoform B", "aln": "--------------------------------------------------------------------MAPKKAKKRQ------QAEGGSSNVFSMFEQSQIQEYKE----------------------------------AFTIIDQNRDGIISKDDLRDVLATMGQLNVKNEELEAMVKE--------ASGPINFTVFLTMFGEKLKGA---DPEDVIVSAFKVLDPEATGTIKKEFLEELLTTQCDRFTAEEMKNLWAAFPPDVAGNVDYKNICYVIT-HGEEKEEE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04466-1", "uniprot_id": "MYL11_RAT", "id": "P04466-1", "name": "Myosin regulatory light chain 11", "aln": "--------------------------------------------------------------------MAPKKAKRR-------AAAEGSSNVFSMFDQTQIQEFKE----------------------------------AFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKE--------ASGPINFTVFLTMFGEKLKGA---DPEDVITGAFKVLDPEGKGTIKKQFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVIT-HGDAKDQE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97457-1", "uniprot_id": "MYL11_MOUSE", "id": "P97457-1", "name": "Myosin regulatory light chain 11", "aln": "--------------------------------------------------------------------MAPKKAKRR-------AGAEGSSNVFSMFDQTQIQEFKE----------------------------------AFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKE--------ASGPINFTVFLTMFGEKLKGA---DPEDVITGAFKVLDPEGKGTIKKQFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVIT-HGDAKDQE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A32-1", "uniprot_id": "MYL11_HUMAN", "id": "Q96A32-1", "name": "Myosin regulatory light chain 11", "aln": "--------------------------------------------------------------------MAPKRAKRR-------TVEGGSSSVFSMFDQTQIQEFKE----------------------------------AFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKE--------ASGPINFTVFLTMFGEKLKGA---DPEDVITGAFKVLDPEGKGTIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVIT-HGDAKDQE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02045-1", "uniprot_id": "MYL5_HUMAN", "id": "Q02045-1", "name": "Myosin light chain 5", "aln": "--------------------------------------------------------------------MASRKTKKKEGGAL--RAQRASSNVFSNFEQTQIQEFKE----------------------------------AFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKE--------ASGPINFTMFLNLFGEKLSGT---DAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVIT-HGEEKEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18432-1", "uniprot_id": "MLR_DROME", "id": "P18432-1", "name": "Myosin regulatory light chain 2", "aln": "-----------------------MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATPAPAASATGSKRASGGSRGSR--KSKRAGSSVFSVFSQKQIAEFKE----------------------------------AFQLMDADKDGIIGKNDLRAAFDSVGKIAN-DKELDAMLGE--------ASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06580-1", "uniprot_id": "MLC2_YEAST", "id": "Q06580-1", "name": "Myosin light chain 2", "aln": "-------------------------------------------------------------------------------------MDHSESLTFNQLTQDYINKLKD----------------------------------AFQMLDEDEDGLISRGDLTKIYATLG-KTLTDEEWSKMVPDNDTSTAEVGEEGVSFPIFLSIMGKNLSQFP---EREELEESLKAIGRGHDLNVPLNEVIDSLKEAGFENPEEEFAKLFKLFTTNQQATEERTFRGKLFLDSITD------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .*. : * * : *: ** :* :.**:* : ** :* :.* . *: : . :.*. :*.::.:.: : : ::: :. : . . * . . *. . : : : :: ", "identical_positions": 20, "similar_positions": 48, "identity": "6.85%" }, { "cls_id": "homologset.agr.FB:FBgn0002774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ABZ7-1", "uniprot_id": "A0A8I6ABZ7_RAT", "id": "A0A8I6ABZ7-1", "name": "ATP-dependent RNA helicase A", "aln": "MGDIKNFLYAWCGKRKMTPAYEIRAVGNKNRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEEVPAVGIVPPPPILSDTSDSTASTGEGLPPPMGGPLPPHLALKAAENNSGVESSS----GYGSPG---PTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERVEPYKVFLSPDLELQLQNVVQELDLEIVPPP------VDPSMPVILNIGKLAHFEPS-QRQNAVGVVPWSPPQSNWNPWTSSNIDEGPLAYASTEQISMDLKNELAYQMEQDHNLQSVLQERELLPVKKFEAEILEAISQNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVAVAERVAYERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVLAYPEVRIVLMSATIDTTMFCEYFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPPKDK-KKKDKED------DGGEDDDANCNLICGDEYGPETKLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFG-SHRYQILPLHSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTIS-AATCFPEPFISEG--KRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTN--TGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ-IVFIDDWIRLQISHEAAACITALRAAMEALVVEVSKQPNIISQLDPVNEHMLNTIRQISRPSAAGINLMIGS-------VRYGDGPRPPKMARYDNGSGYRRGYGGGGYG---GGGYGGGYGSGGFGGGFGSGGGGGFGGGFNSGGGGGFGSGGGGFGSGGGGFGGGGGGFSGGGGGGGFGGGRGGGGGGGFGGSGGFGSGGGGYGVGGGGYGGGGGSGGYGGGSGGYGGGGGGYGGGEGYNMSPNSYRGNYGGG-GGGYRGGSQGGYRNNFGGD-YRGSSGDYRGS--GGGYRGSGGFQRRGYGGGYFGQGRGGGGGGGGGY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70133-1", "uniprot_id": "DHX9_MOUSE", "id": "O70133-1", "name": "ATP-dependent RNA helicase A", "aln": "MGDIKNFLYAWCGKRKMTPAYEIRAVGNKNRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEEVPAVGIVPPPPILSDTSDSTASAAEGLPAPMGGPLPPHLALKAEENNSGVESS-----GYGSPG---PTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERVEPYKVFLSPDLELQLQNVVQELDLEIVPPP------VDPSMPVILNIGKLAHFEPS-QRQNAVGVVPWSPPQSNWNPWTSSNIDEGPLAYASTEQISMDLKNELTYQMEQDHNLQSVLQERELLPVKKFEAEILEAISSNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVAVAERVAYERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVLAYPEVRIVLMSATIDTTMFCEYFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPPKDK-KKKDKED------DGGEDDDANCNLICGDEYGPETKLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFG-SHRYQILPLHSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAIIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTIS-AATCFPEPFISEG--KRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTN--TGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ-IVFIDDWIRLQISHEAAACIT-IRAAMEALVVEVSKQPNIISQLDPVNEHMLNTIRQISRPSAAGINLMIGS-------VRYGDGPRPPKMARYDNGSGYRRGYGGGGYG---GGGYGGGYGSGGFGGGFGSGG--GFGGGFNSGGGG-FGSGGGGFGSGGGGFGGGGGGFSGGGGGG-FGGGRGGGGGG-FGGSGGFGNGGGGYGVGGGGYGGGGG-GGYGGGSGGYGGGG--YGGGEGYSISPNSYRGNYGGG-GGGYRGGSQGGYRNNFGGD-YRGSSGDYRGS--GGGYRGSGGFQRRGYGGGYFGQGRGGGGGGG--Y", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08211-1", "uniprot_id": "DHX9_HUMAN", "id": "Q08211-1", "name": "ATP-dependent RNA helicase A", "aln": "MGDVKNFLYAWCGKRKMTPSYEIRAVGNKNRQKFMCEVQVEGYNYTGMGNSTNKKDAQSNAARDFVNYLVRINEIKSEEVPAFGVASPPP-LTDTPDTTANAEGDLPTTMGGPLPPHLALKAE-NNSEVGAS-----GYGVPG---PTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVVEAYSGLTKKKEGETVEPYKVNLSQDLEHQLQNIIQELNLEILPPP------EDPSVPVALNIGKLAQFEPS-QRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDK-KKKDKDD------DGGEDDDANCNLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFG-SHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIA-AATCFPEPFINEG--KRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTN--TGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQ-IVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGS-------TRYGDGPRPPKMARYDNGSGYRR--GGSSYS---GGGYGGGYSSGGYGS---------------------------------GGYGG-----------------------------------------------------------------------------SANSFRAGYGAGVGGGYRGVSRGGFRGNSGGD-YRGPSGGYRGS--GGFQRGGG---RGAYGTGYFGQGRGGGGY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3F9-1", "uniprot_id": "A0A8M1P3F9_DANRE", "id": "A0A8M1P3F9-1", "name": "RNA helicase", "aln": "MADIKNFLYAWCGKKKLTPNYDIRAAGNKNRQKFMCEVRVESYSYIGMGNSTNKKDAQSNAARDFVNYLVRTKEISPGEVPALGVSVPDG-PSEGGNDDGGGFGNLPS--NCPLPPHLAVKKELESCEGSAPVPGVTGLGYSGRNNAPWERGANLQEYYSKKEEQDAKATYESEEVDLNAGLHGNWTLDNAKARLNQFFQKEKNQTDYKYSQVGPDHNRSFIAEMTIFVRQLGRRVTAREHGSTKKLAAQSCALSLVRQLYHLGVIEAYTGQTKKKEGESVDVYPVNVNDDVQHQLYSVVQELGIHIPPPP------QDPNSPVSLVQGKLAHFEPS-QRQSMAGVVPWSPPQVNWNPWTSSNIDEGPLAFCTPEQISNDLLNELNYQLEQDQNLQTILTERSQLPVKNFQEQIMSTIYNNPVVIIRGATGCGKTTQVPQYILDEFIKGGRASDCNIVVTQPRRISAVSVAERVSFERGEDVGKSCGYSVRFESFLPRPHASILFCTVGVLLRKLESGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPDVRVILMSATIDTTMFKEYFFNCPVIEVHGRAHPVQEYFLEDCIQMTQFVPPPMDR-KRKDKDD------EGG-DEDVNCNVICGSEYSPETKRAMSQLNEKETSFELIEALLKYIETLEVPGAVLVFLPGWNLIYSMQKHLEMNPHFG-GHQYRILPLHSQIPREEQRRVFEPVPDGVTKVILSTNIAETSITINDVVFVLDSCKQKVKLFTSHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFEKLETHMTPEIFRTPLHEVALSIKLLRLGGIGNFLSKAIEPPPLDAVIEAEHTLRELDALDSNDELTPLGRILAKLPIEPRLGKMMIMGCIFNVGDAVCTIS-AATCFPEPFISEG--KRLGFVHRNFAGSRFSDHVALLSVFQAWDEVRVGGEDAEIRFCEHKRLNMPTLRMTWEAKVQLKEILVNVGFPEECLLNQVFNN--VGPDNNLDLVISLLTFGSYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSNHDLKYPSPFFVFGEKIRTRAISAKSMTLVSPLQLILFGSKKITSNGE-VVELDDWIKLQIPHDVAAGVAGLRAGLEALVVEVTKDPEYIRNLDPLNERLLNVIRLVSRPSSAGINLMASN-------PRFGDGPRPPKMARTDFGG------GGDFRG---GGGYRGG---GGYRGG-------------------------------GGGYRGG----------------------------------------------------------------------------------GGYQGG-GGGYRGGGGGGYRGYGGGGGYRG-SGGYRGSSGGGGYGGGGRGFRGGGGGGGGGWGGNRGGY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24785-1", "uniprot_id": "MLE_DROME", "id": "P24785-1", "name": "Dosage compensation regulator mle", "aln": "-MDIKSFLYQFCAKSQIEPKFDIRQTGPKNRQRFLCEVRVEPNTYIGVGNSTNKKDAEKNACRDFVNYLVRVGKLNTNDVPADAGA------SGGGPRTGLEGAGMAGGSGQQKRVFDGQSGPQDLGEAYRP--------------LNHDGGDGGNRYSVIDRIQEQRDMNEAEAFDVNAAIHGNWTIENAKERLNIYKQTNNIRDDYKYTPVGPEHARSFLAELSIYVPALNRTVTARESGSNKKSASKSCALSLVRQLFHLNVIEPFSGTLKKKKDEQLKPYPVKLSPNLINKIDEVIKGLDLPVVNPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKRQESSVIPWAPPQANWNTWHACNIDEGELATTSIDDLSMDYERSLRDRRQNDNEYRQFLEFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRKLEAGLRGVSHIIVDEIHERDVNSDFLLVILRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFPEECMISHEVDERIDGDDPVLDVSLALLCLGLYPNICVHKEKRKVLTTESKAALLHKTSVNC--SNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPLQVILFGSRKIDLAANNIVRVDNWLNFDIEPELAAKIGALKPALEDLITVACDNPSDILRLEEPYAQLVKVVKDLCVKSAGDFGLQRESGILPHQSRQFSDGGGPPKRGRFETGRFTNSSFGRRGNGRTFGGGYGNN--GGGYGNN-------------------------------GGGYGNIGG--------------------------------------------------------------------------GYGNNAGGYGNN--GGY-GNNGGGYRNN-GGG-YGNNGGGYGNK--RGGFGDSFESNRGSGGGFRNGDQGGRWGNF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.*** :*.* :: * ::** .* ****:*:***:** .* *:*********:.**.********* ::.. :*** . : . .:. . . . . : . : * . : * .. *: : *:* .*:**.:*****::*** *** : *.:: : :***: ***:* ***:**::*:: *.* : *** **.** *::**********:**.*:*.::* ***:.* :. * * :. :: :: .::: *.: : * .* *: : .:: : . :::. .*:**:*** ***.* :.***** ** : :::* * ..* : ::*:: : .* *. **: :. :*: :* .*.****** ********:.*:***::* ..:.. .** *********::*****: ** *: *.: ********.:***:.:*:************:*:**:**:*********:*:*****:***:* :**:::::********: * :** **::** **:.***::**** ****.*:*.. .: *:*: :* :. : : * * :* .:*. :*: :*: *.*.:..***:**** :*:: ::***:**********::: *.*: . ** :*:*** ******:***:**:*** ****:*************:*:*:*:* ** ::****:***:*.*************************** *******: ** ::***:*******:**:*******.* :**:**:****:**:**** ***: .**:*********:**:******:****::*.:* .* :. :: :: *.* * : :**. :: ::*.: *****:: . * * : **. * ***: * *:*.*:.: *:** ** ::* : ****:*::.: . : * * **: ::** :* ***:* ******:****.: **:**:**** *. :.:* *************:*.* :::*:***::**.*:*: .: :* :*:*:.::* : ** : ::..:* *:. . .:* * .*: :::: :: :. *:..:.* . ::.** *** .* : * * . **** .. **: . **: . ..* . *** * . **:*. **. * . .*.* .. * .. * . * * . * ", "identical_positions": 580, "similar_positions": 379, "identity": "40.45%" }, { "cls_id": "homologset.agr.FB:FBgn0002775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N5Y2-1", "uniprot_id": "MS3L1_HUMAN", "id": "Q8N5Y2-1", "name": "MSL complex subunit 3", "aln": "MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN-RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLP------------------------GVDSVLKGLPTEEKDENDENSLSSSSDCSE-NKDEEISEESDIEEKTEVKEEP---ELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHH--VMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C860-1", "uniprot_id": "MS3L2_HUMAN", "id": "P0C860-1", "name": "MSL complex subunit 3B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEERTVTLEIPEVLKRQLEDDCYYINRRKRLVQLPCHTNIITILESYVKHFAISAAFSANERPRHHH--AMPHASMNVPYIPAEKNIDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTASKVFLAIKESATNTNRSQEKLSPSLRLLNPSRPQSTESQSTSGEPATPKRRKAEPQAVQSLRRSSPHTANCDRLSKSSTSPQPKRWQQDMSTSVPKLFLHLEKKTPVHSRSSSPT-LTPSQEGSPVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFTEKNLKALLKHFDLFVRFLAEYHDDFFPESAYVAASEVHYSTRNPQAVNKC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A9H7-1", "uniprot_id": "A0A8I6A9H7_RAT", "id": "A0A8I6A9H7-1", "name": "MSL complex subunit 3", "aln": "MSASKGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWNSSSWDRWAAEDHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLP------------------------GVDSVLKSVPVKEKTKNDENSISSTCHESCGEKNGGIKEHRQRRIKVKTKGKKKVLSLRSRKDMDERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHH--AMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSTSMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVG9-1", "uniprot_id": "MS3L1_MOUSE", "id": "Q9WVG9-1", "name": "MSL complex subunit 3", "aln": "MSASEGMKFQFHSGEKVLCFEPDPTKARVLYDAKIIDVIIGKDEKGRKIPEYLIHFNGWN-RSWDRWAAEEHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRRCRLP------------------------GVDSVLKSVPVKEKSKNDENSVSSTCHESCGEKNGGIKEHRQRRIKVKAKAKKKVLSLRSRKEMDERTITIDIPDVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHH--AMMHTHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGEPATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRPNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3X992-1", "uniprot_id": "MS3L2_MOUSE", "id": "G3X992-1", "name": "MSL complex subunit 3B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MATLGCAPKDDGEGKDEGGSDRGDGDSKPKGKKE----------------VEPHTRREADERAMRIPIPEVLQQRLADDCYYINRRRRLVRLPCQTNVGAILECYVRHFSASVLALGDRRPQPQR--AAP-----------ERSVGLCREMADGLRITFDHALPLVLLYPQEQAQYEMVTSSTFFFPTEERASDAGRSQEAPWPG-----PSPPQPSESQAVAG-PAAPKRRRAEAEATRAPRRSTRHSTHCHWQAEDRASPQAKR-------SVPKLFPHLQK-TPVHSAAPSPIALTPGKEGSAMFAGFEG-TTEEINEILSWKLVPDNYPPGHQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHLDLFLRFLAEYQADFFLESAYVSACEAHYSSKNPRTLC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYG1-1", "uniprot_id": "MS3L2_RAT", "id": "Q6AYG1-1", "name": "MSL complex subunit 3B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MATLGCAPKDDGEGKDEGGSDRGDGDPKPKGKKE----------------VEAHTRREADERAVRIPIPEVLQQRLADDCYYINRRRRLVRLPCQTNVGAILECYVRHFSASALASGDRRPQPQR--AAP-----------ERSVGLCREMADGLRITFDHALPLVLLYPQEQAQYEMVTSSTFFFPTEERASDAGRSQEAPWPG-----PSPPQPSESQAMAG-PTAPKRRRVETDAARAPRRSTRHSTHCHWQAEDRASPQAKR-------SVPKLFPHLQK-TPVHSTALSPIALTPGKEGSAMFAGFEG-TTEEINEILSWKLVPDNYPPGHQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHLDLFLRFLAEYQADFFLESAYVSACEAHYSSKNPRTIC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50536-1", "uniprot_id": "MSL3_DROME", "id": "P50536-1", "name": "Protein male-specific lethal-3", "aln": "MTELRDETPLFHKGEIVLCYEPDKSKARVLYTSKVLNVFERRNEHGLRFYEYKIHFQGWR-PSYDRCVRATVLLKDTEENRQLQRELAEAAKLQIRGDYSYKGTPDKPSAKKKRGGKAAHVEEPIVVPMDTGHLEAEHEMAPTPRAAGNRTRDNSGGKRKEKPPSGDGRLKGNRGRQTETFYNNAINDVSVYNHVPQEDRIMMRVSERLRELIEYDRNMIKVLGKQHALPARVPIVTIMENFVKQQAVELAISIKQDSSRARNTQSRNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYTEEKEYVHNYLTDDN---MRNCSLILNKSYEYINPS---------GDTELIGLDGTPVVEGSGDTNGQIGVINIGGPEYEKQLQKCLLYIVTASGKN-----------TAQAYERTSPYTAAYKLPVEMRG-----------------FLNETFKWRLLSAESPPEK-----SMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLEN-HREWFDRENFVNSTALPQEDLQRELLDSLDGIAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : :.: *:. : * *: : **.:. : :*:* :*:: : . .. . : .: : :*:.***** *:. : ***. *: . :. .: : .:* * *. :* * *.. .: : .. : : . :.. *. :: :* : * : :** :.*:*:. : ** . * ::** **:**::*:* :*. .:::*:*: ** *:* *:.:* : : ::* .. :* : . : . : ", "identical_positions": 55, "similar_positions": 104, "identity": "9.84%" }, { "cls_id": "homologset.agr.FB:FBgn0002778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PMI3-1", "uniprot_id": "A0A8M9PMI3_DANRE", "id": "A0A8M9PMI3-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "--------MSSGGTRRRTASVP-------DSDPDGEP----------------AVTLKKEIGLLSACGIVVGNIIGSGIFVSPKGVLENSGSVGLALIVWILTGIITAIGALCYAELGVTIPKSGGDYSYVNDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFANYALQPLFPSCFPPERALGLLAAVCLLLLTWINCSSVRWATRVQDVFTTGKLLALGLIIIMGIVQICK----GHFYWLEPEHAFHPLQPYDMGRIALAVLQGSFAYAGWNFLNYVTEELIDPYRNLPRAIFISIPLVTFVYVSANIAYVTAMSPQELLASNAVAVT--FGEKLLGVMSWLMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPRLLAMIHVNRCTP----IPALLITCISTLLMLCVSDIYTLIN-YVGFINYLFYGVTVAGQIVLRIREP----DIYRPIKVSLAWPAVFLIFWAFLLIFSLYSEPVVCCIG-----LAIMLSGVPVYLFG-----IYWENKPKSFSSFVARLTHLGQKLCLVVYPGED---REDGNEDREEDG------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WVR6-1", "uniprot_id": "LAT2_RAT", "id": "Q9WVR6-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "--------MEKG-TRQRNNTAKNHPDRGSDTSPEAEASSG-----------GGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGVITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGVVQICK----GEFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLASNAVAVT--FGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP----IPALLFTCLSTLLMLVTSDMYTLIN-YVGFINYLFYGVTVAGQIVLRWKKP----DIPRPIKISLLFPIIYLLFWAFLLIFSLWSEPVVCGIG-----LAIMLTGVPVYFLG-----VYWQHKPKCFNDFIESLTLVSQKMCVVVYPQEGDSGTEETIDDVEEQHKPIFQPTPVKDPDSEEQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z127-1", "uniprot_id": "LAT1_MOUSE", "id": "Q9Z127-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "--------MAVAGAKRRAVATPAAAAAEEERQAREKMLEARRGDGADP--EGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDMGQGDASNLQQKLSFEGTN-LDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTSEAVAVD--FGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSVLSMIHPQLLTP----VPSLVFTCIMTLMYAFSRDIFSIIN-FFSFFNWLCVALAIIGMMWLRFKKP----ELERPIKVNLALPVFFILACLFLIAVSFWKTPMECGIG-----FAIILSGLPVYFFG-----VWWKNKPKWILQAIFSVTVLCQKLMQVVPQET----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63016-1", "uniprot_id": "LAT1_RAT", "id": "Q63016-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "--------MAVAGAKRRAVAAPATTAAEEERQAREKMLEARRGDGADP--EGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDIGQGDASNLHQKLSFEGTN-LDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTSEAVAVD--FGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCVMTLMYAFSRDIFSIIN-FFSFFNWLCVALAIIGMMWLRFKKP----ELERPIKVNLALPVFFILACLFLIAVSFWKTPLECGIG-----FAIILSGLPVYFFG-----VWWKNKPKWILQVIFSVTVLCQKLMQVVPQET----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01650-1", "uniprot_id": "LAT1_HUMAN", "id": "Q01650-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "--------MAGAGPKRRALAAP---AAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGK----GDVSNLDPNFSFEGTK-LDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVD--FGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCVMTLLYAFSKDIFSVIN-FFSFFNWLCVALAIIGMIWLRHRKP----ELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIG-----FTIILSGLPVYFFG-----VWWKNKPKWLLQGIFSTTVLCQKLMQVVPQET----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y1A7-1", "uniprot_id": "Q9Y1A7_DROME", "id": "Q9Y1A7-1", "name": "", "aln": "--------MARVQASDSLIPRQVFEVPPAEPNNSTADSGS----------QGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFD----GNTEHWDNPFS-GGLQ--DPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVT--FGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTP----VPSLIFLGVLTLLLLFIEDVYVLIN-YVSYVEALFTLISVSGLLWMRYKQP----KTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIG-----TIIILSGIPVYYLT-----IHKP--VKWLADTSQAINLWCSKFFICMPNQEKFD-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCGSVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLT--AADTEVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGG-LKDGYQSHNFRNAFEGTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGGQAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::: ::. .:: . ::*:*:*. .. : .** * :*::* .::: * * *:*. *.*.**: *: : *: :: :: : * . . :. : . :*. .*: : : : *: : .* * : . . : : :. *. . ::: *:. :*:. *: :* :.* * *: .::.:*: .*:**.:.:. :::::*. : . *. * . *. * :*.: . :*:..*:: .*:* ** : : .. : .: *:: * : ::: ..: : * : : :. . *** .: . .: : :*: . . : : . :: : : : .. : ", "identical_positions": 55, "similar_positions": 158, "identity": "9.52%" }, { "cls_id": "homologset.agr.FB:FBgn0002787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26516-1", "uniprot_id": "PSMD7_MOUSE", "id": "P26516-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPN-SVLVIIDVKPKDLGLPTEAYISVEEVHD------DGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVASGKLPINHQIIYQLQDVFNLLP----------DAS-------LQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEK-EESK-KERKDDKEK------EKSDAAKKEEKKEKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AEH3-1", "uniprot_id": "D4AEH3_RAT", "id": "D4AEH3-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPN-SVLVIIDVKPKDLGLPTEAYISVEEVHDLSLFSQDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRTYLEKVASGKLPINHHIIYQLQDVFNLLP----------DAS-------LQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEK-EESK-KERKDDKEK------EKSD-AKKEEKKEKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51665-1", "uniprot_id": "PSMD7_HUMAN", "id": "P51665-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPN-SVLVIIDVKPKDLGLPTEAYISVEEVHD------DGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLP----------DVS-------LQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEK-EESK-KDRKEDKEKD--KDKEKSD-VKKEEKKEKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26270-1", "uniprot_id": "PSMD7_DROME", "id": "P26270-1", "name": "26S proteasome non-ATPase regulatory subunit 7", "aln": "MPSQEVSVNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPN-SVLVIIDAKPKDLGLPTEAYISVEEVHD------DGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKITNQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLP----------DIT-------NDQFTGTMYVKTNDQMLVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNKDSKDKDNKETKDKDGKKAEEKADKGKDEGGKGSRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08723-1", "uniprot_id": "RPN8_YEAST", "id": "Q08723-1", "name": "26S proteasome regulatory subunit RPN8", "aln": "MS---LQHEKVTIAPLVLLSALDHYERTQTKEN-KRCVGVILGDANSS-TIRVTNSFALPFEEDEKNSDVWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPKLRASDLKINELFKKYTQNNPLLLIVDVKQQGVGLPTDAYVAIEQVKD------DGTSTEKTFLHLPCTIEAEEAEEIGVEHLLRDVRDQAAGGLSIRLTNQLKSLKGLQSKLKDVVEYLDKVINKELPINHTILGKLQDVFNLLPNLGTPDDDEIDVENHDRINISNNLQKALTVKTNDELMVIYISNLVRSIIAFDDLIENKIQNKKIQE-----QRVKDK--QSKVSDDSESESG------DKEATAPLIQRKNKKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :** : ******.:**::* . * ** ***:** ... .: *:****:**:**:*:..******:*:*** * **:**:*:::****:****: .*: ****.::* * .:*:*:*.* :.:****:**:::*:*:* **:.*.*** *:.. * ******:********::* :.* ** ::***: .****:::* *: **::* ::**** *: :***:***** * ::: :: :****:::*:*::.::**::*:.:**:**: *:. :: :. ::* :** .: .: :. :* * .: ", "identical_positions": 145, "similar_positions": 116, "identity": "40.06%" }, { "cls_id": "homologset.agr.FB:FBgn0002789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFX0-1", "uniprot_id": "TAGL2_RAT", "id": "Q5XFX0-1", "name": "Transgelin-2", "aln": "--MANRGPSYGLSREVQQKIEKQYDPDLEQILIQWITTQCRKGVSQPQPGRENFQNWLKDGTVLCELINSLYPEGQAPVKKIQAS--TMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37802-1", "uniprot_id": "TAGL2_HUMAN", "id": "P37802-1", "name": "Transgelin-2", "aln": "--MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQAS--TMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVA4-1", "uniprot_id": "TAGL2_MOUSE", "id": "Q9WVA4-1", "name": "Transgelin-2", "aln": "--MANRGPSYGLSREVQQKIEKQYDADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKIQAS--SMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1Q8-1", "uniprot_id": "TAGL3_MOUSE", "id": "Q9R1Q8-1", "name": "Transgelin-3", "aln": "--MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37805-1", "uniprot_id": "TAGL3_RAT", "id": "P37805-1", "name": "Transgelin-3", "aln": "--MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRTHFQKWLMDGTVLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UI15-1", "uniprot_id": "TAGL3_HUMAN", "id": "Q9UI15-1", "name": "Transgelin-3", "aln": "--MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37804-1", "uniprot_id": "TAGL_MOUSE", "id": "P37804-1", "name": "Transgelin", "aln": "--MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPENPP-SMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLYEGKDMAAVQRTLMALGSLAVTKNDGNYRGDPNWFMKKAQEHKRDFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31232-1", "uniprot_id": "TAGL_RAT", "id": "P31232-1", "name": "Transgelin", "aln": "--MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVMQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPENPP-SMVFKQMEQVAQFLKAAEDYGVTKTDMFQTVDLFEGKDMAAVQRTVMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01995-1", "uniprot_id": "TAGL_HUMAN", "id": "Q01995-1", "name": "Transgelin", "aln": "--MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPP-SMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14318-1", "uniprot_id": "MP20_DROME", "id": "P14318-1", "name": "Muscle-specific protein 20", "aln": "--MS-------LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKF----PAGQSYEDVLKDGQVLCKLINVLSPN---AVPKVNSS--GGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHAD--FKG-PFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQN-LGAGRKILLGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08873-1", "uniprot_id": "SCP1_YEAST", "id": "Q08873-1", "name": "Transgelin", "aln": "MSYDKKADVTSLDEDLRQLRESKFSPEAIQNIKIWVYKSVLKEIAPP----GDLLECLKDGTVLCKLANILYEADTGEANHISWKSSKMPFVQMDQISQFLSFSRKYGVPEDELFQTIDLFEKKDPAIVFQTLKSLSRYANKKHTDRFPVLGPQLSTKKPRPPVKSKPKHLQDGTGWSTFEYGYMKGASQATEGVVLGQRRDIV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :: .: . : : *: . * :* :*.:* * * . * *::: :* . . **: ::***:**:* *: * * .*: *. : : : . . .:*: * :: * :**:** *: : ", "identical_positions": 31, "similar_positions": 46, "identity": "15.05%" }, { "cls_id": "homologset.agr.FB:FBgn0002791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EWF8-1", "uniprot_id": "F7EWF8_RAT", "id": "F7EWF8-1", "name": "Anaphase-promoting complex subunit 2", "aln": "MEAEGVAVS-VAAAAAATTTIVATDDCDSRPGQELVVAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRAHGLHSVLEEWFVEVLQNDLQGNIATEFWNAISLRENSVDEPQ-CLVLLLDAFGLLESRLDPYLHSLELLEKWTRLGLLMG-AGAQGLR--EKVHTMLRGVLFFSTPRTFQEMVQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFNQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVG-WLGKVFLQDNPSRPTS-PEAGNTLRRWR--CHVQRFFYRIYASLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKVALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPACLETGQDSEDDSGEPEDWVPDPVDADP----AKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSP-EREIRNVELLKLRFG-----------------------------EAPMHFCEVMLKDMADSRRINANIREEDEKRPVEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALDVYCKKYEKLKNWRLEPGLLVWLLTTCLPGMALVQVIGARAIPCWVAWYRTYALFIWTCLEPTGLFLMIPAQAMRTLSWKHTLGLVTMDVELAD-RTLSVAVTPVQAVVLLYFQDQAS----WTLEELSKVVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEE-ERPQ-DRDNMVLIDSDDE-SDSGMASQADQK-EEELLLFWTYIQAMLTNLESLSLERIYSMLRMFVMTGPALAEIDLQELQGYLQKKVRDQQLIYSA-GVYRLPKNCN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZQ7-1", "uniprot_id": "ANC2_MOUSE", "id": "Q8BZQ7-1", "name": "Anaphase-promoting complex subunit 2", "aln": "MEAEGVAVAAAAAAAAAAATIIASDDCDSRPGQELLVAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQGNIATEFWNAIALRENSVDEPQ-CLGLLLDAFGLLESRLDPYLHSLELLEKWTRLGLLMG-AGAQGLR--EKVHTMLRGVLFFSTPRTFQEMVQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFNQLSQVLHRLSLLERVCAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVG-WLGKVFLQDNPTRPTS-PEAGNTLRRWR--CHVQRFFYRIYATLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKVALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPACLETGQDSEDDSGEPEDWVPDPVDADP----VKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSP-EREIRNVELLKLRFG-----------------------------EAPMHFCEVMLKDMADSRRINANIREEDEKRPVEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALDVYCKKYEKLK-------------------------------------------------------------AMRTLSWKHTLGLVTMDVELAD-RTLSVAVTPVQAVVLLYFQNQAS----WTLEELSKVVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEE-ERPQ-DRDNMVLIDSDDE-SDSGMASQADQK-EEELLLFWAYIQAMLTNLESLSLERIYSMLRMFVMTGPALAEIDLQELQGYLQKKVRDQQLIYSA-GVYRLPKNSN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX6-1", "uniprot_id": "ANC2_HUMAN", "id": "Q9UJX6-1", "name": "Anaphase-promoting complex subunit 2", "aln": "---------------MAAAVVVAEGDSDSRPGQELLVAWNTVSTGLVPPAALGLVSSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSADEPQ-CLLLLLDAFGLLESRLDPYLRSLELLEKWTRLGLLMG-TGAQGLR--EEVHTMLRGVLFFSTPRTFQEMIQRLYGCFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQFHQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVG-WLGKVFLQDGPARPAS-PEAGNTLRRWR--CHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADP----GKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSP-EREIRNVELLKLRFG-----------------------------EAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLK-------------------------------------------------------------AMRTLSWKHTLGLVTMDVELAD-RTLSVAVTPVQAVILLYFQDQAS----WTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEE-ERPQ-DRDNMVLIDSDDE-SDSGMASQADQK-EEELLLFWTYIQAMLTNLESLSLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSA-GVYRLPKNCS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1E5-1", "uniprot_id": "Q9W1E5_DROME", "id": "Q9W1E5-1", "name": "Anaphase-promoting complex subunit 2", "aln": "---------------MCDFDALWADVLRIFP---VLGGANAVSNDPVEENVF--QNVRQHLMVLGSIDTFAAVVDLEIQSTIRNVLVPKFWKHIHDGLVSSKLQGWINDQALAIEALPDKNGLFTQFIDAINELHDSFQSLMQVKPRLIQLVGAETKPT-AKTVKLMQEEGIKNCLRDCLLAQLPPNFSVVVGAFYWVHFKLFTKASNLALTTVDSDVFDEL----------------LCVGCNFEAEQCCCQRLTDMVNKTNMKLFEMNLIDRLTGSALTALIKLKIKEHISDTCMGIFDRSHLKQLETWLSDVIMSWLTNIFTEWKSKDSISDIEVPESVKSFK--VKLTYFMYETFAQSVIGQFFSIIIDYPDSIPAIDDLKICMEKIDMRVYLTESLRNSLEARILHPGVNTMDILTGYVAAIKAIRHLDSTGVILEMVTAPIKDYLRKRNDTVRRVVTGLTEE--GPTDLSEELAKG-ETIKECKDSGTDEFSNWENWQPDPFGIDASIMQYNSSRKMRSADIISMVVDIYGSKELFMTEYRNLMADRLLAQLDFNS-EKEIRNLELLKIRFG-----------------------------ESLLHSCEVMLKDVTDSKRINAHIHSDGDR---TENQLFDISSLIVSAQFWPSFNKESLQLPEEIENEFKKYTKAYEAYK-------------------------------------------------------------GNRTLNWRTVTGRVNIEIEIGD-RTMEMVVSPILAVIIYHFQTKNE----WTIEDLSSITKVPASALRRRLSFWQNHGLISETTPGIFTLLEK-ESEKSQYEDMSLAEADEEDLESAMASASDQR-EEELQVFWSYIVGMLTNLDSMPIDRIHQMLKLFASHS-GGVEFTQDELKHFLQRKVREHKLIFSG-GVYQLAK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12440-1", "uniprot_id": "APC2_YEAST", "id": "Q12440-1", "name": "Anaphase-promoting complex subunit 2", "aln": "-----------MSFQITPTRDLKVITDELQTLSSYIFHTNIVDDLNSLLTWMSPNDAKSNHQLRPPSLRIKNIIKVLFPN---NATTSPYSMINTSQANNSIVNEGNTNKELQLQLFSTLKEFYIFQVRYHFFLHFNNINYLKDIQRWENYYEFPLRYVPIFDVNVNDWALELNSLRHYLLNRNIKFKNNLRTRLDKLIMDDDFDLADNLIQWLKSANGSLSS------------TELIVNALYSKINKFCEDNMSRVWNKRFMIMETFNKFINQYWSQFSKLVGCPEDD-------HELTTTVFNCFESNFLRIRTNEIFDICVLAYPDSKVTLLELRKIMKDFKDYTNIVTTFLSDFKKYILNPSVTTVDALLRYVKTIKAFLVLDPTGRCLHSITTFVKPYFQERKHLVNVLLYAMLDLPEEELKEKINFNVDMKALLSLVDTLHDSDINQDTNITKRDKNKKSPFLWNLKVKGKRELNKDLPIRHAMLYEHILNYYIAWVPEPNDMIP----GNIKSSYIKTNLFEVLLDLFESREFFISEFRNLLTDRLFTLKFYTLDEKWTRCLKLIREKIVKFTETSHSNYITNGILGLLETTAPAADADQSNLNSIDVMLWDIKCSEELCRKMHEVAGLDPIIFPKFISLLYWKYNCDTQ-GSNDLAFHLPIDLERELQKYSDIYSQLK-------------------------------------------------------------PGRKLQLCKDKGKVEIQLAFKDGRKLVLDVSLEQCSVINQFDSPNDEPICLSLEQLSESLNIAPPRLTHLLDFWIQKGVLLKEN-GTYSVIEHSEMDFDQAQKTAPMEIENSNYELHNDSEIERKYELTLQRSLPFIEGMLTNLGAMKLHKIHSFLKITVPKDWGYNRITLQQLEGYLNTLADEGRLKYIANGSYEIVKNGHKNS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * *. : . : : : :.: .. : . . . : : : *. :: : : . ** *: . : : : . .. . : . . :: . :: : :. : . . .: : : : :. :.. : : : .: . : * : :: :: :: : : : .: : :*. : : :: :: * .* :: :* :: * .:: .:: .: : . . .: : . . . * *:* . . : . . .::::.:::.:: *:::*:.*:*.*::***: :. *: * ::*:: :: :: :: :*** *: *..: :::. :.: ..: :. :.:* ::. :. * . *. * *.*. * * ::: : * *.: : *: . :: *: . ::*:**. ::. . * : :..* ::*:: : * ::::*. * : :. : ::. : * ::: * * .:* .***** :: :.:*:.:*:: . . . .: ::*: :*: . : :* : . * *.: * ", "identical_positions": 69, "similar_positions": 257, "identity": "7.24%" }, { "cls_id": "homologset.agr.FB:FBgn0002878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM39-1", "uniprot_id": "A0A8I6GM39_RAT", "id": "A0A8I6GM39-1", "name": "DNA topoisomerase 2-binding protein 1", "aln": "MTPLPPEEALRPLVWRESRFLVLALPGTAALTSGWGRRRGRGLRAGLAPDPSRRPAGRAPPDLVPVGPRAPPSSAMSRNDQEPFFVKFLKS-------SDNSECFFKALESIKELQSEEYLQVITDEEALRIKEN----DKSLYICDRFSGTAFDHLKQLGCRIVGPQVVTFCMRHQQCVPRAEHPVYNMIMSDITISCTSLDKDKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPAWIKTLWEKSQ--EKKITKYTDVNMEDFKCPIFLGCIICVTGLNGIHRKTVQQLTAKHGGQYMGQLKMNECTHLIVQEPK--GQKYECARRWNVHCVTLQWFHDSIEKGFCQDESIYKAEPRAAVKTVPDTSTPTAQSGSAAAENHRLADVSHISNINGSCVNETMFGSTTSKLECT-----------------LENLENLDISMFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIMGDYEDDVRQFWSKSSHR--PHVVGAKWLLECFSKGYILPEESYIHANYQPDGIPVSDQPRNQTTVLEK-SGTFSKKDFVPNEKFQQTDEDLLAQYVHD--DSTIVEAKLSEAIEPEVGPCGGSAHVEPCDDSTHISVQE------ENKSSVSHCLLDGSTVPEEGLFSQKSFLVLG--------FSVENECNIVNIIREHAGKIVSLPSRIVADYAVVPLLG----CEVEATVAEVVTNTWLVTCIDNQTLVDPKSNPLFTPVSVMSGMTPLEDCVISFSQCVGAERDSLVFLANHLGASVQEFFVRKSNAKKGMLASTHLIVKEPTGSKYEAAKKWSLPAVNISWLLETARMGKRADENHFLVDSAPKQEQVLETNIPNGVSPNPDSPAHPDAHLEIHRQKAVTPLDMNRFQSKAFHAVISQHNRQGLASPPVRQPPKKEPSFHLDTPSKFLSKDKLFKPSFDVTDALAALETPNAASQ-KRKLSSPLSEVIVRNLTTALANSSRNTGCLSASPQLKGAHLEKEETPKPLDKVVVCVSKRLSKKQSELNGVAASLGAEYRWSFDETVTHYIYQGRANDSNREYKSAKERGVHVVSEHWLLECAQEYKHLPESLYPHTYNPKMSLDISTVQDGRLCDSRLPSALSASKDDEPDHLSVEENATETLGTHSRESALLNGNGRDDCKGALTQALEMRENFQKQLQEIMSATSIVRTPAQKTCMSRSSCNSASSTPDSTRSARSGRSRVLEALRQSRQIVPDINTEPSQNEQIIWDDPTAREERARLASNLQWPSYPTQYSELQVEIKKLDDSPSRKPVYHSEIAGQASC------VTQAPGQHPGSEEPEAPAAERNLIPEPQAPSVAFPLAKPPVAPQPEDKIETLEETHGKLKKQYVFQMSSLNSQE-RIDYCRLIKDLGGSVIEKQC-SDPSCTHMVVGYPLRNEKYLASMAAGKWVLHRSYLDACRTAGRFVQEEDYEWGSSSILDALPDVTEHQQKLALAAMRWRKRIQQSRESGIAEGAFSGWKVILRVDRPREAGFKRLLQAGGAKVLPGHP----EPLFKDATHLFCDFNKLKPDDCRVFIAEATAQNMVCLKTEYIADYLMMESPPCADNYRVSETALFR--NKEGGPGLPQKRKTPAEN-VIKRPRVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQF0-1", "uniprot_id": "TOPB1_MOUSE", "id": "Q6ZQF0-1", "name": "DNA topoisomerase 2-binding protein 1", "aln": "---------------------------------------------------------------------------MSRNDQEPFLVKFLKS-------SDNSECFFKALESIKELQSEDYLQIITDEEALKIREN----DKSLYICDRFSGTVFDHLKQLGCRIVGPQVVTFCMRHQQCVPRAEHPVYNMIMSDVTVSCTSLDKDKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQ--EKKITKYTDVNMEDFKCPIFLGCIICVTGLNGIHRKTVQQLTAKHGGQYMGQLKMNECTHLIVQEPK--GQKYECARRWNVHCVTLQWFHDSIEKGFCQDESIYKAETRVEAKMVPDTSTPTAQSN---AESHTLADVSHISNINGSCVNETMFGSTTSKLECS-----------------LENLENLDISMFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDDVRQFWSKSSHR--PHVVGAKWLLECFTKGYILPEESYIHTNYQPAGIAVSDQPGNQTAVLDK-SGSFSKSALVPAERLQQADEDLLAQYGND--DSTMVEAKLSEALEPEVGPCPGSAHREPCDDSTHISVQE------ENKSSVSHCILDDSTVREEGLFSQKSFLVLG--------FSVENKCNIVDIIREHAGKIVSLPSRIVADYAVVPLLG----CEVDVTVGEVVTNTWLVTCIDNQTLVDPKSNPLFTPVSVMSGVTPLEDCVISFSQCVGAERDSLVFLANHLGASVQEFFVRKANAKKGMLASTHLIVKEPTGSKYEAAKKWSLPAVNISWLLETARIGKRADENHFLVDNAPKQEQVLETKIPNGVSSNPDLPAHPDAHLEIHRKKAVTPLDMNRFQSRAFRAVISQQRGQDPTFPPVRQPLTKEPSLHLDTPSKFLSKDKLFKPSFDVTDALAALETPNAASQ-KRKLSSPLSEVIVRNLTVALANSSRNTDSHSASPQLKGAHLEEEETRKPLDSVVVCVSKKLSKKQSELNGVAASLGAEYRWSFDETVTHFIYQGRANDSNREYKSAKERGVHIVSEHWLLECAQEYKHLPESLYPHTYNPKMSLDINTVQDGRLCNSRAPLAVSASKDDGPDHLSVEGNETNTMGTNDKESPLLNGSGRDDCKGALTQALEMRENFQKQLQEIMSATCIVKTPAQKTCMSRSSCNSASSTPDSARSVRSGRSRVLEALRQSRQAVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSDPTQHSELQVEIKMPDDSPSRKPVYHSEIAEQASC------VTQAPG-HPGSEEPEPPVAERPLIPEPQAPAVASPLAKPPVAPQPADKIETQEETHRKVKKQYVFQMSSLNSQE-RIDYCRLIKDLGGSVIEKQC-SDPSCTHMVVGYPLRNEKYLASMAAGKWVLHRSYLDACKTAGRFVQEEDYEWGSSSILDALPDVTEHQQKLALAAMRWRKRIQQSQESGIVEGAFSGWKAILRVDRPREAGFKRLLQAGGAKVLSGHP----EPLLKDATHLFCDFNKLKPDDCRVFIAEATAQNMVCLKTEYIADYLMLESPPCADNYRVSEAALFH--NKKGGPGLPQKRKTPAEN-VVKRPRVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92547-1", "uniprot_id": "TOPB1_HUMAN", "id": "Q92547-1", "name": "DNA topoisomerase 2-binding protein 1", "aln": "---------------------------------------------------------------------------MSRNDKEPFFVKFLKS-------SDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKEN----DRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQ--EKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPK--GQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQIN--TIDSRTLSDVSNISNINASCVSESICNSLNSKLEPT-----------------LENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHR--PHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHKPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENG--SSTVVEAKTSEAR-----PFNDSTHAEPLNDSTHISLQE------ENQSSVSHCVPDVSTITEEGLFSQKSFLVLG--------FSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLG----CEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSTKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKPSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLSKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSSTKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSTRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPK-HPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKIITIEETHEELKKQYIFQLSSLNPQE-RIDYCHLIEKLGGLVIEKQC-FDPTCTHIVVGHPLRNEKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINVQQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLLQSGGAKVLPGHS----VPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY97-1", "uniprot_id": "Q9VY97_DROME", "id": "Q9VY97-1", "name": "", "aln": "----------------------------------------------------------------------MSISMSMDETICAYFVNNLKPGDGGVQEADTLQQFEAARELLGQQLAETQIRQIKPSEGYPLIAAGNLTKKDVFVLTQFEGEFFEQLQQTRALILGPPCLITCLRRNEPIPEGSSAIYSTAMRDLQVSATGITPQKKEELSRLINWMGGIYFQSFGHRTTHLISNTIKSSKYEQATLNGVPVMHVDWVQYVWDQSRRSQREGIMATDPDFDKYRLPIFFGANITCSGLDVARKDQVMRLVNDNGGIYHRAFRSQVVDIVITEQTKTDTEKYKAAIRYKKDVLLPEWIFDSCNRGYALPTKDYEVRPGKTSSTPTKTTRPGAAPGADQTHLSDLSRISFVSGSRRMCSDLSTVNESVSSVGSSSPAKQLLKQATSSGRNYQQVLAEIEPRQAKKAGAFLDGCCVYLSGFRSEEREKLNRVLNTGGATRYDEANEGISHIIVGQLDDAEYRQWQRDGLMGSVHVVRLDWLLESIRAGRVVS--ELVHRVSMPQNREPDVASPASKRTLRSMNHSFKQPTLPIKKKLFDQEPDPVQEQEHEEPDHTLLDQYSQDQGAVAQLPPADVSLLQPAASSTQMDIRQRVSVANPKPPAEGLQLPDLSASTLSIDFDKLDYFAGVSVYVHRECFNEEFFNQMLTECEAAQGLLVPSSFSDEVDFAIVSFEVAFDVKQLPVKARHVVTELFLESCMKKNQLLPIEYYHKHVPATALR--QPLKGMTIVVSIYAGLERDFINATAELLGASVNKTFIKKE--------KPLLVCPSAEGSKYEGAIKWNYPVVTSDWLVQCARTGQKLPFVGYLVGKSPE-----DFPISPRLRDSNSRTARRPNESTLVAQPDVTMEEAENQPAGSVTPVTAGSPGAPELTPLRNKRVSELAGIPGGS----------------------ALHRGSNSTSSPDSPCTPLSQVGAQQYNLDFLEQFVQR-------------LDTEEGKDCVREIIREMRENQTPELERIRRQACTPVSRKHQRPAPGIPDFCLTP----------EFQQRMADDFERRWRLPTMKIKPDTPLAVIRQRVMRITCETLGIEYEESNAKTPTLSESPSTVKKKPP-----------------------------TRTTQATKLNFDRSPKTPKLSLGKKTPLRVSMGSPRSGTQSPFVPNTQSPIEAAPPRRSDGPTLSEEGQSTINFDKISFEESAVPVLAPDVPTVAPDVKQITDYLKN--CESRRNSLKRSHDNDMDCGESEVQYVQPFESEGFA--------------LGTEDMVDWRDPAEFNAAKRRSSGGSPKMQYAGIP--------------------CFSISCGDDDEKRAELIARITQLGGKVCENLVNYDDSCTHLLCERPNRGEKMLACIAAGKWILNIQYIEQSHARGDFLDETLYEWGNPKAIN-LPTLAPEEEPIAAAVHRWRTELSACGG-----GAFSDHRVILSMNERSGAPIRNVLRAGGACILEPTTPFSKDPVAKSASHCFVDVKKAPLSTQDMEYLHKCG--VQVLSQIAINAYLMNGRDADLGKYQLL-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47027-1", "uniprot_id": "DPB11_YEAST", "id": "P47027-1", "name": "DNA replication regulator DPB11", "aln": "---------------------------------------------------------------------------MKPFQGITFCPTAINN-------EILAKKISKKIIKLGGIFSKDLTRQVNVLVVGSTTNT----NKFKFAVKHRFDIIFIDIQAIDD------IYQLWLSGENILPDS--------------NTATMTGSTYEMLKILYRRFSFKYLHNFNIFIGRITDTNITSIDSLVRSIKKLGCSSYNYQNFVIKDTS-----------------------------------------SHNDDDDQGQNGQISIFVTDTLLGARVN-------AAIEQNIPIVHFKWILDCQKRSALLPYDPYYLLPN-------IKDLPYDSIGSNSCDCWDKINTTFPTNIDAQSSLQRQQSSSTLTPSLP------------------------------------------------------------------------KTSSLLNKFKPKGEKIWDK-----------------------AMSLQQHSKTNFSVLGQSPLSINNKQEDLSDNSTLIFKNCAFIIHHIFPGNHRSILTKIVVQ-------------------------------------------------------NGGKIETSYLSGIYDHSYYIIPSN-------KALDSFNDLPEIIDDNDG---------------------------------IVTEFFIERCLYYQKLLHP------------------------IDLWSKPFLSTIEFQVSSS---------------------SKLLHHEFSSSPFLNVTITGFSGVELLHLTKVLN---------------------------------------------LLKPMGINYVEYLNKSTDILLINLAALPSIPKTHPLWSN-----------------------------------------------EFSDLFTQFCINNNNDDPG--------------------DNNRKDFQNNSILRNSMKRKIEYIKKFHSIPVVTPAFIFKLLSAAS------------------GENNEIFLNNIKWCIICPRGHKDDFKCKIKKPYYTSISSEKKYQNNDPKIDKTILLKRNNSS---------------------------------------LSEHSMKDTKNELLQKIRETDSGRKKR------SVSSSIMDVSSERQMPDTKRIKLESLPKNFVPKQIKRTTSWGTIMSENVPTEQPTAISNPEEIPRTEEVSHTQVTYGSIQDKKR--------------------------------------TASLEKPMRRQTRNQTKELDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :: : : : :: : :. .: : . * .:: : :. :* . . : : .. * : . :. :.:. :: : * . : : : : ..: ... : :: . : .* . : : :*: *. ::. . * . . * . . : :. . .. . . : ::.. . : *.: :. : . . . *.: : . . . : : . .: . :.: :: : :: * :**: :: *: : *. .. . : .. . *: . .* : . . . * * : . :. : . : . : * : . . :::. .: : :. .:: :. ..:. . : ::. . :* : : . . : . : .. : .: . : .: . : * .: . : * . . : : **. : .:. : ..:: . : . . : ", "identical_positions": 26, "similar_positions": 214, "identity": "1.56%" }, { "cls_id": "homologset.agr.FB:FBgn0002891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61493-1", "uniprot_id": "REV3L_MOUSE", "id": "Q61493-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "---------------------MFSVRIVTADYYMASPLPGLDTCQSPLTQLPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQ---------------PESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKCYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGNASHATG--------LFKHQLSGNSPAGTLFR-WEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGG---NPGLQAIWEDEKQRRRNRNESSQISQPESQDCRFVPATESEKQFQKRLQEVLKQNDFSV-TLSGSVDYSNGSQEFSAELTLHSEILSPEMLPCSPANMIEVHKDTDL-SKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMGSSPDESLVHLLAGLESDGYQGEKNRMPLPCHSFGESQNPQNSDDEENEPQIEKEEMELSVVMSQRWDSDIEEHCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKDGLTEDLSQPNS-TEKGRDNSVT-FTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVSSCESSVFDYEEDIPSVTRQVPSRKYSNMRKIEKDASCIHVNRHISETILGKNSFNFADLNHSKRKLSSEGNEKGNSTSLSGVFPSSLTENCDLLPSSGENRSMAHSLESITDESGLNKLKIRYEEFQEHKMEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSP------VTYKLQ-SGNKPSRLKLNKKKLIGLQETSTKSTETGATKDSCTHNDLYTGASEKENGLSSDSAKATHGTFENKPPTEHFIDCHFGDGSLEAEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTQNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKPGKQHRTNSENIKRTLSFRKKRTHA---VLSPPSPSYIAETEDCDLSYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKESMLFKGPNVYNTKTVSPRVGKASRARAQVKKSKARLANSSVVTNKRNKRNQTTKLVDDGKKKPRAKQKQRANEKSLSRKHAIPADEKMKPHS--EAELTPNHQSVSELTSSSG-AQALSKQKEMSQTGPAVDHPLPPAQPTGISAQQRLSNCFSSFLESKKSVDLRTFPSSRDDSHSSVVYSSIGPGISKINIQRSHNQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQVCSGIISPKTEESSSTQKNCGSSMGKLNEYRSSLESKPEQVCAPNFLHCKDSQQQTVSVSEQSKTSETCSPGNAASEESQTPN-CFVTSLKSPIKQIAWEQKQRGFILDMSNFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQSTNVVQDSTS-THQPDKNISVSNEHKKANKRTRPVTSPRKPRTPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEH--NYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIDKSELLSHDRQSCSEEKHHVSDSSPWIRASTLNPELFEKVAMDNNENHRHSQWKNSFHPLTSHSNSIMESFCVQQAENCLTEKSRLNRSSVSKEVFLSLPQANSSDWIQGHNRKEADQSLHSANTSFTTILSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGQAVVNKESSNSHKMVEDKKIVIMPCKYAPSRQLVQAWLQAKEEYERSKK----LPKTELTPVTKSAENVSPSLNPGDTCAVSPQVDKCPHTLSSSAHTKEEVSKSQIALQTSTTGC------SQTLLAAASAAVPEEDEDD---------NDNCYVSYSSPDSPGIPPWQQAASPDFRSLNGDDRHSSPGKELCSLAVENFLKPIKDGIQKSSCSESWEPQVISPIHARARTGKWDPLCLHSTPVMQRKFLEKLPEATG-LSPLSVEPKTQKLYNKKGSDADGLRRVLLTTQVENQFAAVNTPKKETSQ-IDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRSQTPLLIRSGITGLEVTYAADEKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALS-VDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLS-DWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQIRHD--VTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYKQD-RALSRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIIYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKA-----TSSSRSELEGRKGTISQYFTTLHCPV-CDDLTQHGICSKCRSQPQHVAIILNQEIRELERKQEQLIKICRNCTG---------SFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8G6-1", "uniprot_id": "F1M8G6_RAT", "id": "F1M8G6-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "---------------------MFSVRIVTADYYMASPLPGLDICQSPLTQHPVKKVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGYGQQ---------------PERYLSQMALSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGDASHATG--------LFKPQLSGNSPAGTLFR-WEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGG---NPGLQAIWEDEKQRRRNRNENSQISQPESQDCRLVPATESEKIFQKRLQEILKQNDFSVRTLSGSVDYSSGSQEFSAELTLHSEILSPEMLPCSPANMIEVHRDNDW-SKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMDSSPDESLVHLLAGLESDGYQGEKNRMPLPRHTFGESQNPQNSDDEENAPQMEKEEMELSVLMSQRWDSDTEEQCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSVFHKDAATLEPPSSAKITFQCKHTSALSSHGLNKDDLIEGLSQPNN-TEKGRDSSVT-FTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVPSCESSVFDYEEDIPSVTRQAPSRKYSNMRKIEKDAPFIHANRHTSESTLGKNSFNFADLNHSKNKLSSEGNERGNSTALNSVFPSSLAESCDLLSSSGENRSVAHSLDSITDESGRSKLKIRYEEFQEHKMERPSLSQQAAHYMFFPSVVLSNCLTRPQKLSP------VTYKLQ-PGSKTSRLKLNKKKLISLQETSTKSSETGAAKDSCTHNHPYSGTPEKESGLSSDLIKATHGTFENKTPTEHFIDCHFGDGSLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKRKPGKQHRASSENIKRTLSFRKKRTHA---VLSPPSPSYIAETEDCDLNYSDVMSKLGFLSERSTSPVNSSPPRCWSPTDPRAEEIMAAAEKESVLFKGPNVCNTKTVSPRVGKASRARAQVKKSKARLAKSSVVTNKRNKRNQTNQLVDNGKKKPRAKQKQRANEKGISRKPVIPTDETTKPPS--EAELTPSQRSVPELTSSSG-IHTLSKQKEMTQTGPAMDHPLPPCQPTGINAQQRLSNCFSSFLESRKSVQFPTFPSSRGDSRSS-VYSSIGPGVSKVNTQRSHSQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQLCSGIISPKTEESSNTQKNCGSSIGKLNEYRSSLESKPEKVCAPNFLHCRDSQQQTVNVSEQSKPSETCSPGNAASEESQTPN-CFVTSLRSPIKQITWEQRQRGCILEMSSFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQTTN-VQDSAS-SHQPDKDISVSAEHKKTNKRTRAVASPRKPRAPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEH--NYNFDINTIGQTGFCSLYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNELLSHDRQSCTEEKHHVSDSGPWVRASTLNPELFEKVGIDNNENHRHSQWKTSFHPLTSHSNSIMESFCVQQAESCLPEKSRLNRSSVSKEVFLSLPQASSSDWIQGHNGKEIEQSLDSANTSFTTVLSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGPAVVNKESSNSHKTVEDKKIVIMPCRYAPSRQLVQAWLQAKEEYVRSKR----LPRTESTPVIKSADNVSPSLNPGDTRAVAPQMDTCPHTLSSTAHAKEEVCQSQIALQTSRTGCGQTVSASQTLLPAASAAVPEEEEEEEEEEEEEEEDENGYVSYSSPDSPGIPPWQQAASPDFRALNGEHRCSSPVEELCSRAVENFLKPIKDGIQKASCCES---QVISPIHARTRTEKCEPLCLHSTPVMPRKFLEKLPEATG-LSPLSVEPKTQKLYNKKGSDTDHLRRVLLTTQVENQFAAVNTPKKETSQ-IDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRCQTPLLIRSGVTGLEVTYAADEKALFQEVTNIMKRYDPDILLGYEIQMHSWGYLLQRAAALS-VDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLS-DWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHIENLGKYDEFKFGCTSLRVPPDLLYQIRHD--ITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYRQD-RALSRMLNARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIVYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKA-----TSSSRSDLEGRKGTISQYFTTLHCPV-CDGLTQHGICSQCRSQPQHVAIILNQEIRELERQQEQLVKICRNCTG---------SFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60673-1", "uniprot_id": "REV3L_HUMAN", "id": "O60673-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "---------------------MFSVRIVTADYYMASPLQGLDTCQSPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQ---------------PESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPTMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSNTLHATG--------SCKNHLSGNSLADTLFR-WEQDEIPSSLILEGVEPQSTCELEVDAVAADILNRLDIEAQIGG---NPGLQAIWEDEKQRRRNRNETSQMSQPESQDHRFVPATESEKKFQKRLQEILKQNDFSV-TLSGSVDYSDGSQEFSAELTLHSEVLSPEMLQCTPANMVEVHKDKES-SKGHTRHKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFMDSSPDEALVHLLAGLESDGYRGERNRMPSPCRSFGNNKYPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEEHCAKKRSLCRNTHRSSTEDDDSSSGEEMEWSDNSLLLASLSIPQLDGTADENSDNPLNNENSRTHSSVIATSKLSVKPSIFHKDAATLEPSSSAKITFQCKHTSALSSHVLNKEDLIEDLSQTNKNTEKGLDNSVTSFTNESTYSMKYPGSLSSTVHSENSHKENSKKE-ILPVSSCESSIFDYEEDIPSVTRQVPSRKYTNIRKIEKDSPFIHMHRHPNENTLGKNSFNFSDLNHSKNKVSSEGNEKGNSTALSSLFPSSFTENCELLSCSGENRTMVHSLNSTADESGLNKLKIRYEEFQEHKTEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSP------VTYKLQ-PGNKPSRLKLNKRKLAGHQETSTKSSETGSTKDNFIQNNPCNSNPEKDNALASDLTKTTRGAFENKTPTDGFIDCHFGDGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGESLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNNENIKRTLSFRKKRSHA---ILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKEAMLFKGPNVY-KKTVNSRIGKTSRARAQIKKSKAKLANPSIVTKKRNKRNQTNKLVDDGKKKPRAKQKT--NEKGTSRKHTTLKDEKIKSQSGAEVKFVLKHQNVSEFASSSGGSQLLFKQKDMPLMGSAVDHPLSASLPTGINAQQKLSGCFSSFLESKKSVDLQTFPSSRDDLHPSVVCNSIGPGVSKINVQRPHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSGMSSKIEDNANNIQRNYLSSIGKLSEYRNSLESKLDQAYTPNFLHCKDSQQQIVCIAEQSKHSETCSPGNTASEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKPRSLSEAISQTKALSQCKNRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANTTQDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPRKPRTPRSTKQKEKIPKLLKVDSLNLQNSSQLDNSVSDDSPIFFSDPGFESCYSLEDSLSPEH--NYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNEFLSHDNQKCDEDKHHTTDSASWIRSGTLSPEIFEKSTIDSNENRRHNQWKNSFHPLTTRSNSIMDSFCVQQAEDCLSEKSRLNRSSVSKEVFLSLPQPNNSDWIQGHTRKEMGQSLDSANTSFTAILSSPDGELVDVACEDLELYVSRNNDMLTPTPDSSPRSTSSPSQSKNGSFTPRTANILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPEKPREIGGRLLMVETRLANDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRSGQGVVNKGSSNSPKMVEDKKIVIMPCKCAPSRQLVQVWLQAKEEYERSKK----LPKTKPTGVVKSAENFSSSVNPDDKPVVPPKMDVSPCILPTTAHTKEDVDNSQIALQAPTTGCSQTASESQMLPPVASASDPEKDEDD---------DDNYYISYSSPDSPVIPPWQQPISPDSKALNGDDRPSSPVEELPSLAFENFLKPIKDGIQKSPCSEPQEPLVISPINTRARTGKCESLCFHSTPIIQRKLLERLPEAPG-LSPLSTEPKTQKLSNKKGSNTDTLRRVLLT-QAKNQFAAVNTPQKETSQ-IDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKALFHEIANIIKRYDPDILLGYEIQMHSWGYLLQRAAALS-IDLCRMISRVPDDKIENRFAAERDEYGSYTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLS-DWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQVRHD--ITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYKQD-RALSRMLDARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGACVPALELTRKMLTYDRRSEPQVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPRIHKA-----TSSSRSEPEGRKGTISQYFTTLHCPV-CDDLTQHGICSKCRSQPQHVAVILNQEIRELERQQEQLVKICKNCTG---------CFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T757-1", "uniprot_id": "A0AB32T757_DANRE", "id": "A0AB32T757-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "----------MSCSVWFCRINMFSVRIVTADYYMSSPIRELDVCYSEFRESDVKKVPVVRIFGATPAGQKTCLHLHGIFPYIYVPYDGFGQE---------------ADRYLRQVAYSIDRALNISMGNPSSNVQHIFKVVLVTGMPFYGYHMREKSFMKIFLYNPQMVKRVSELLQAGAVMNKSFQPHEAHIPFLLQLFIDYNLYGMNMISLAAVKFRKSRATASEEEQMGGGTSPLRNACASTFNETGLRDTLCTRWEENNIPSSLILEEVERVSVCELEVDAVAADVLNRLEIENQIGR---NPGLQAIWDDEKQRRRQRSESSHIDVTESQDRDLAEVAESEKIFMKRVKDILRENEFDMTQAGSEMDS-------FPDLSLYSTVLSPDRLPSIHASQVDLHQDAVKDTKRDSRKDDEVAVVDEEAILSMLENSQSFLQLSQTSSQSAIFDGSQ-EQAMVDLLEALANDGF-GDKSSKAVTQQLTGIASCVYNSDDEEAGPELEKKESELSKIMSQRWDSDIPEPSARQR-LFMKANESSSEEQQASSDEEGNWKGINSFQTDLSIPQLDGAADESSDSSLKEKGSQRRSYITGTDKILASRKVFANEAVRIEASSSVNIVNEYKCSEQRP----DREDLADKHSKCGESIESSNISSLK-EVTPVKHPISSNSRITYKVDSDH--------------PDLEDLMFGNSKLAQSIK------KYSSIKHVEKNTLLILEDQRSS-------SACYSGLTDSATKTKIVLNPSDCRS------PVKVFDQTQTLEDSPALGPEESEMGQGTKEDDVGELKIRYEDYQENKADRTIVAQQEAHYKFFPSVILSNCLARPIKKQAGSKIGEVSCTLDQPEQRKSRLKLTKKKPTLDQKRELPVKTHSPTKEEPPALLSITPGSHNQNEVSKEVDMETSGSLIESSGKGDFADIPTN---ISCTKVASLPGSKYTLRTKRKRIYEKGDHPRSGSSKQASVHHDDPKGS-----DHVFSQKKRKVTKKEPPVIIKYIIINRFKGQKNMLVKISKVSSDETHTVLTPEKLAGYEQLAPLKKFWPKIPESTAEKYPSLEPKVKKCPKRKAKINPVVKRMTTFPKSKCPRVGQTRGERRAKAMLPVQTLAPPWPSYNDFTDDTCTEYCDVMMKLGYLSERAPSPTDSTPPRCWSPT----EHLHGSNSNDHFINPHNDPCLGSSCEALTPKPSQSGLLNRSRMQRPKKTSGTSQKRKSNSLTTATNKGSLKTEDSKWKS---IPAASRKHKKYCDG-------------IERPMFVDVTSTSQ-KGWMRNEKQLLQR--KQDHGKGSNNSQGLNSSDNLP--VTQLSDYLTPFQCPSFLKSNPEDLALGCSDSKTEVHSFFDSIASNNSQKDLRIAPNSTIEKSFSILS----QPTKTVGHPCSVITYGSSNSKSKNTSQDGTKTKNHDVISVVSGHEERSGT-----VQQSQLPITSRRPQARKKDTG------------------TALLKPVDSISSPTSS--------------TKSAAIYESNTDLTLSSDFKNR-------------EMCVLKELLQKRQLKEEQEANKSDGLT---EAVSSTSQNTDVAKRAKSKRTLSSP--SRKPRGARTKVQTRCKK-----NKQDDQRNDCLSSDGSPVFFSDPGFDSCCSVEDSLSPELPDNYRFDINVIGQTEFSSLYSGNQFVLTDKILPQKFLSDVSQEAAN--ALVGLGNRTQKMFDVDDDFNHGNDRN---KSGALSPELFDKVSCE---NGRVFPNKVSLSLLDSEK---IFSTNWAGSLGKIHGLSHFRDFHCEKRDVLLDPEPKSP--------------IMSASFAYG---VSPNSDLLDGS---------------SLTPSSSPRSINSLSQLKTS--RTGGTRILKPLMSPPAREEILANLMDLDFSEATKQEPFYSDPSDVPLKPREVGGRKLILETRQASRLVEFHGDLSQNGLQFWKVAFSAMTNQASAPTQGCKSSKLIKNQSPSS---VSDPKVIILPCKCAPSREQVQLWAQAKKQYECLQRGRIQMGGHEISELKQSTCDRSTTQKTSN-SLFSENHDKRPEKNSESQHNSRNDFCSPIHFSPVKAAS------SDSSPSSVKCVQDIDKTKD-------------CRITSPPNSPEISTWQD--SPD--EVEQDEDKENLTGGLQPLSMDQNLN---ETLLENAESKDHLSPSFFGIKGLVSDVRCS-HLLHSTPVQRRNSTDDEASSCSPVRHEDTECRSQRLHQRSNKNKNALRRVLLSTQVKNQLINMNVPKKENSQ-IEGPSFCNSYGFKVSMQNLQEAKALHEVQHLTLMSMELHARTRRNLEPDPEFDPICALFYCLSSDVLLHDSGTTRIEGAIVIDKESCTSAQASRSSTPFLFRCGVTGLPVTYTCDEKELFEEVSNIIRKYDPDILVGYEVQMHSWGYLLQRASTLG-VNLCQQLSRVPGDSQQNHFIPEKDEYGAETMTEIHITGRIILNIWRIMKTEAALNNYTFENVAFHLLHQRYPLYSHRTLS-DWFD--THLHRWKVMDHYVSRVCGTVQLLQQQDIIGRTSELARVFGIQFYHVLTRGSQYRVESMMLRVAKPMNYIPVTPSTQQRAQQRAAQCIPLVMEPESRFYSNSVIVLDFQSLYPSIVIAYNYCYSTCLGHIENLGTYDEFKFGCASLRVPPDLLYQLRND--ITVSPNGVAFVKSSVRRGVLPRMLEEILKTRIMVKQSMKAYRND-KALSRLLDARQLGLKLIANVTFGYTSANFSGRMPCVEVGDSIVHKARETLERAIKMVNDTKKWGARVVYGDTDSMFVLLKGATKEQAFKIGNEIAEAVTATNPKPIKLKFEKVYLPCILQTKKRYVGYMYESVDQENPVFDAKGIETVRRDGCPGVSKILERSLKLLFESRDISQVKQYVQRQCVKVVEGKASMQDLTFAKEYRGSGSYRPGACVPALELTRRMMAFDRRLEPRVGERVPYVIVYGSPGVPLIQLVRRPLEVLQDPSLRLNATYYITKQILPPLARIFNLIGVDVFSWYHELPRVQRAW--SFTSSGRGEEGTKKGTISQYFTTLHCPV-CDELTQLGVCARCRAEPQCVAVHLHQDLRLWESQQDQLLKICRSCSG---------SAERQVPCVSLDCPILYKLSRVNRNLSRGPYLRQLVEQFL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GSR1-1", "uniprot_id": "DPOZ_DROME", "id": "Q9GSR1-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "-----------MAAAGEAIDGVYSVRLVIADFYMEKPQFGMDPCYSELRGKEIKRVPVIRVFGGNSRGQKTCMHVHGVFPYLYIPYDKKDFES--------------LERGILQMAMHLDKAINISLGQGSSNAQHVFKIQLVKGIPFYGYHRVEHQFLKIYMFNPRFVRRAANLLQSGAILSKNFSPHESHVPYILQFMIDYNLYGMSYVHVPLEVLKFRRNHDDDVIPYAN----------------------------VKQAQLLDITTAKKVACSALEVDVSSNFILNRFQLVAKSKSNHTNPGIEAIWNDEKLRR-QKLVEKHTDAGDEEKAEAVPVLELPPTQERHQIEIAESDIFYRTALES------------KLMTLEQSTLSEQTLSDQTILPQATMQTTMPGTKAQKRRFNLQKLLANAVYPEECSQDQQQLLVNASFIQNHVTCGYS-----------------------------------------------------SSVSLSTSKDESDDLDETVVDEELILSLTQPHGAIPHDATLREE-----------DLELLDALQLLEEQNESESHVDLDSSLAPLSQHKKFELTPELLDKETAATAALFDEDVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDEDADQETRHDFSTVLDDVDELLLKLTQSQPAESKELKASSKLPQIDGADDRLQRTPIKSISSKSK---------------SSPSKTPTTPIGQKSLPKSPRTPKTSAAKKYAPLALTIGSSSSKKSNDEFAGRPSNPRLSLQLDQGTG-----------------------------TGTLRPEISLRKKLAMSEMRRKSFEDSFVLLKNDCTPVRSTRRSTSNLDKTHIICSLTPRDRNPGLSDMFETEDGKQLPPKKVVRKTRWSTRNQDIESLPKAGCEIERPHRSEGSALDELKPRRSARHKVNSANPDECSSEIQTTGPRVTTTSLDRPQKKAR--------------------------------------------------------------------LSQSPKENTKTSMNGTVALEKATKDSSSNSESPHQQENSVSEQIEYLESKPKKSDETARSCDEKLQR----------------------------------------------------------------ELIPQEPAGISPG-----------DSANSTEEITFSPCHDEAIESDTESD-----YIVTKLRKTPNLKRLRWSIRSELLN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQFTPSSGIRPPETETTPQLSPKSNES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------NTPELMRSFYEHSLIVNSPSVFSDFLDSPEIHMD------------------------------------------------------SPRSAPPSPDS------------NSFVIAPLELPPSYDEVVSGSRKMDIPEYEFQKPYYSNPSDVS-KVTEVGFLVLHIPGNKLNDCDPFQSILGND------RGLASWRRRQLIAIGGLAMLQRHRGEQKVREYFSTQQRIAIEPAQLAPTWQEAKIWLKAKELLRQREE------------PKKSSDDIDSPIKIKRQKITMMLQAEEGDGGSGDEDAGEELDCS---------------------------------------------------------------------------------------------------------------------LSLTPLSQAKDKCKATPTSSKARETGKSRLKRGTRLSFIGSQDEEPPSSQSSEQSVSSSAAQAELDRSSFLRQLEGSSQDRQHDLSFGLSHATLDNTFGFKVNLENLQQAKADIDCNHLTIITLEVFVSTRGDLQPDPMHDEIRCLFYAIEHSLPDEKLPSKACGYIMVNTVQDLLSEGP--------FHGIDRDIEVQVVTSEAEAFEALLALCERWDADIYAGYEIEMSSWGYVIDRAKHLC-FNIAPLLSRVPTQKVR-DFVDEDREQFTDLDVEMKLCGRILLDVWRLMRSEIALTSYTFENVMYHILHKRCPWHTAKSLT-EWFG--SPCTRWIVMEYYLERVRGTLTLLDQLDLLGRTSEMAKLIGIQFYEVLSRGSQFRVESMMLRIAKPKNLVPLSPSVQARAHMRAPEYLALIMEPQSRFYADPLIVLDFQSLYPSMIIAYNYCFSTCLGRVEHLGGSSPFEFGASQLRVSRQMLQKLLEHDLVTVSPCGVVFVKREVREGILPRMLTEILDTRQMVKQSMKLHKDS-SALQRILHSRQLGLKLMANVTYGYTAANFSGRMPSVEVGDSVVSKGRETLERAIKLVENNEEWKVRVVYGDTDSMFVLVPGRNRAEAFRIGEEIAKAVTEMNPQPVKLKLEKVYQPCMLQTKKRYVGYMYETADQEQPVYEAKGIETVRRDGCPAVAKMLEKVLRILFETQDVSKIKAYVCRQFTKLLSGRANLQDLIFAKEFRGLNGYKPTACVPALELTRKWMQKDPRHVPRRGERVPFIIVNGPPGMQLIRLVRSPHDILANEGHKINAIYYITKAIIPPLNRCLLLIGANVHDWFASLPRKLLMTPAVGTANELAGARGAKSTISQYFSTTSCVIDCGRQTKAGICPDCLKNATTCVVVLSDKTARLERGYQLTRQICQACCG---------RLG-SLQCDSLDCPVLYVLEGKRRELQQIEHWNKLLEHHF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14284-1", "uniprot_id": "DPOZ_YEAST", "id": "P14284-1", "name": "DNA polymerase zeta catalytic subunit", "aln": "MSRESNDTIQSDTVRSSSKSDYFRIQLNNQDYYMSKPTFLDPSHGESLPLNQFSQVPNIRVFGALPTGHQVLCHVHGILPYMFIKYDGQITDTSTLRHQRCAQVHKTLEVKIRASFKRKKDDKHDLAGDKLGNLNFVADVSVVKGIPFYGYHVGWNLFYKISLLNPSCLSRISELIRDGKIFGKKFEIYESHIPYLLQWTADFNLFGCSWINVDRCYFRSPVLN-----------------------------------------SILDIDKLTINDDLQLLLDRFCDFKCNVLSRRDFPRVG------------------------------------------------------------------------------------------------------------------------NGLIEIDILPQFIKNREK----------------------------------------------------------------------------LQHRDIHHDFLEKLGDISDIPVKPYVSSAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMINELTMQREELSLKEYKEPPETKRHVSGHQWQSSGEFEAFYKKAQHKT------------------STFDGQIPNFENFIDKNQKFSAINTPYEALPQLWPRLPQIEINNNSMQD--------------------------------------------------------------------------------------------KKNDDQVNASFTEYEICGVDNENEGVKGSNIKSRSYSWLPESIASPKDSTILLDHQTKYHN--TINFSMDCAMTQNMASKRKLRSSVSANKTSLLSRKRKKVMAAGLRYGKRAFVYG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPPFGYQDILNKLEDEGFPKIDYKDPFFSNPVDLENKPYAYAG-----------------------------KRFEISSTHVSTRIPVQFGGETVSVYNKPTFDMFSSWKYALKPPTYDAVQK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WYNKVPSMGNKKTESQISMHTPHSKFLYKFASDVSGKQKRKKSSVHDSLTHLTLEIHANTRSDKIPDPAIDEVSMIIWCLEEETFPLDLDIAYEGIMIVHKASEDS-------TFPTKIQHCINEIPVMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIHQFDIVRELARVKCQIKT----KLSDTWGYAHSSGIMITGRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHFSFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKSPLIVLDFQSLYPSIMIGYNYCYSTMIGRVREIN-LTENNLGVSKFSLPRNILALLKND--VTIAPNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNNKQLALKLLANVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKDETWNAKVVYGDTDSLFVYLPGKTAIEAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLPIFDAKGIETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFCFAKEVKLGAYKSEKTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVSPEEFLEGENLELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKSKRAS-------TTTTKVENITRVGTSATCCNCGEELTKICSLQLCDDCLEKRSTTTLSFLIKKLKRQKEYQTLKTVCRTCSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYLRDNQSVQREEALISLNDW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: *:** .* . : ..:** :*:**. . *::. *:**::**::: ** : : : . : *: .. :.: .: :*.*:****** . * ** : ** : * .:*:: * ::.* :. :*:*:*::** *:**:* . : : :: . * : * :* . * :. :: . .: : : : * : . .: . .:* :: : . : .. :.: . : . . * . . . . .. . : . * .: . . :. * . : : . . :: .. . . . .: : : * . :::: . .:.: :.*: *:* *: * . : . . . : : * . : : : : . : . : * .:.. *: * : ** :::*:.. ** : *** * : :::.:. . . :* .. :: : * .* *. : : *.** *:*:. ****:::*. : .:: ::** : : : ** :::** ::.: *..**:*.. :::**:* * .: . *: * : ::::::.*. .: :* : * :.:. * *:::**:* * ****::***:::*:.*. . : ::*. : : :* : :.*:***:* ** ..::**********::*.****:** :*::..:. ::* :.: :. ::* : .. :*::* **.:.* .**.. *.:** :**..* *:*::*: :. :*.*:*. :**.***:****:***:*.******. ::.**:* ..*****:**.:::. : * .:********:** : * . ::* **. :*: ** **:*: **:**** *.:* :******: **: .* *:::**********. *. *::*: :::**:::*:* :* *: .: *: *:.. **: **** : :. .. :.:: : * * *: **:*:::: * * * . * :.* . .::: ***.* ::*** * : *** :* .* .: : :. : * . :* * : .: : . : : :*: * * * :**::: .* * .: ", "identical_positions": 298, "similar_positions": 440, "identity": "9.21%" }, { "cls_id": "homologset.agr.FB:FBgn0002899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT19-1", "uniprot_id": "E9PT19_RAT", "id": "E9PT19-1", "name": "Helicase POLQ-like", "aln": "MEESSPRIRRRVSLRKRNRRSLESLGAARAPAELQPAED--TEDEAAAGSRRRKTG--------------SPE-----------------------PAQENDSEEDMFGDYNSFSENSFLAQVDDLEQKYIQLPDCGSRGTDSGTKDLCSEGLGNSLSVP-AVDFTDSETREYIKKQGDLDVPVEPEVGGDLSFDMPSSQILYFESMQNSSKDLGDQSTKGRDG-----KSSNEELHHSHREQPQPKSD-FSDVGGSSEASRRRSIKDCLKSAMTGNARAQTPAFPRSKQLRETLLSEEISVARKAIESPSDDLGPFYSLPSKVRDLYAQLKGIKRLYDWQHTCLTLSSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLLILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKGHSLVNALIETGRMGTLGLVVVDELHMIGEGSRGATLEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSR---AVDGMTFSRLLNYKYSDALKKVDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSR-DYLNHREEEKGELIKSLRNVGHGKVCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMIGRAGRAGIDTAGESILLLQEKDKQQVLGLINGPLEDCHSHLVEEFTKGIQSLFLSLIGLKIAESLGDIYQFMNGTLFGVQQKTLLREK---------SLWEVTVGALEHLTEKGLLQKDSHG-SPEESRCH---------------FRITKLGQASFKGAIDLTYCDTLYRDLKKGLEGLVLESLLHLVYLTTPYDLAAQSE----PDWMVYFRQFSQLSPAEQSVATLLGISESFIGRKASGQAIRKKVDKNAVNRLYLSFVLYSLLKETNVWSVSERFNMPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLTELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYRSVVHLANANPEVLVKTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEAEELLRLPADLPGLGGPGSERAGSHAGDLALR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2VPA6-1", "uniprot_id": "HELQ_MOUSE", "id": "Q2VPA6-1", "name": "Helicase POLQ-like", "aln": "MEDGCPRIRRRVSVRKRNRGNLENLRASPTPAELQPAED--TEDEAAAGSRRRKTG--------------SPE-----------------------HAQENDSEEDMFGDYDSFTESSFLAHVDDLEQRYMQLPECGDRDADSGTKDLCSAGLKNNLRVTTVINLTDPETSEHGQKQSHLDVPAEPEPGSDLSFDVPSSQILYFENPQNSPEALGDPCTKKTNGDP--QKSSHEELVSSHTEQPEPNND-FSNVRAASESSRRKSLKDHLKSTMAGNARAQTPAFPRSKHLREALLSEEISVAKKAIESPSDDLGPFYSLPSKVRDLYVQLKGIKKLYDWQHTCLTLRSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLMILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSLVNALIETSRLSTLGLVVVDELHMIGEGSRGAILEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSQ---AADGMTFSRLLSYKYSEALKKMDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSK-DYLNHREKEKCEVIKSLRNIGNGKVCPVLKRTVPFGIAYHHSGLTSEERKLLEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMVGRAGRAGIDTAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKIAASLGDIYQFMSGTFFGVQQKILLKEK---------SLWEITVDALEHLTEKGLLQKDSCG-DNEGLECH---------------FRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYLTTPYDLAAQSE----PDWMVYFKQFGQLSPTEQNVAALLGVSESFIGKKAAGQAVRKKVDKNVVNRLYLSFVLYSLLKETNVWSVSEKFNLPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYNAGYRSIMHLANANPEVLVKTIDHLSRRQARQIVSSAKMLLHEKAEALQGEAEELLRLPADLPGLGGPSSERAGSHAGDVTLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDG4-1", "uniprot_id": "HELQ_HUMAN", "id": "Q8TDG4-1", "name": "Helicase POLQ-like", "aln": "MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEG-VTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK---AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSK-EYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEK---------SLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYN---------------FHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCN----PDWMIYFRQFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVASSTDKA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSE2-1", "uniprot_id": "HELQ_DROME", "id": "Q9VSE2-1", "name": "Helicase POLQ-like", "aln": "-------MANKHNLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSNAH---------------------------------------LEDLLDGRKEELFGTQATTSTN-----------------KMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQ----------NTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCG-ILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLN-RLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEIVSAAKIILMKKLDHLEEETENLKDCLKTSDKN------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: .: *:. .* : : *: :: : . :: :. : ::** : : . . . :* . :.. .: . :. . :: .:: :: . . :*. :... :.* : . : * ::*: .. : : * :*: : * . : : . . :. : .: . . * **.**.**:.: : ***: **:**. **.* ::::******:****************:**** .::**:*****:*****:*.:*.*.*:*.*:****:..**: ** **:::**:**:***. *:::**:. * :*********:*** .*** ** *:*::: . . **:*****:.*:.::. **:*: ** ********::* . : *::* : :. ** :.*:**:::*: ***:*..*::* *::.*******:******* ::.:::.: .:::*:..** :::. * :: :.*** :*:*:*:********::*** :* ** **: :: *************:***:*****.: **. :****:*******:. *****: *.**: * :: *:: . * * :: : *:*:*:**::**::* *: :::..*::.** * * .::: .* * *. ::.. . : . : *::*::*:*:**. ** .: ::::**:. : *:* . ***:**.. :: : : .* : * : .*. .* : **.:*:. .: *:: :. : *** ::* :*: : :*:.::*: ** :*:*: ::: :*.::::******** *:.*: .: :*: * . ** ****:..* .**:*** **:::: .:*...*. **::::*:. * * :***:**::* :* : *: *.*:* ", "identical_positions": 335, "similar_positions": 355, "identity": "29.28%" }, { "cls_id": "homologset.agr.FB:FBgn0002905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A628-1", "uniprot_id": "D4A628_RAT", "id": "D4A628-1", "name": "DNA polymerase theta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLPRRSGKRRRS------------SSGSDSFSFSGDG-DSCVSPQLLCR----------PVLSPPPG-----LGRGRRLAGTGTCKQRVSDDQIDQLLLANWGLPKAVLEKYHNFGVKKMFEWQAECLLLG-QVLEGKNLVYSAPTSAGKTLVAELLILKRVLETRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPTGRFSSLDVAVCTIERANGLINRLIEENKMDLLGTVVVDELHMLGDSHRGYLLELLLTKVCFVTRKSASCQADSASALACAVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKVGNSIYDSSMKLVREFQPLLQVKG----DEDHIVSLCYETVRDNHSVLVFCPSKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILDQKSLLEVIDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPVFGGQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGSLEPVHSCLQSQG--EVTSTMIRAILEIIVSGVASTSQDMQTYAACTFLAADVKEGKQGIQRNR-DDVQRGAVDACVTWLLENEFIQAAEPSDGTGGKVYHPTHLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTP--VFEDWTSIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIHKRFFTSLVLLDLISEIPLKEINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLIRVSSLNAQRARFLYASGFLTVADLARADTVEVEAALKDALPFKSARKAVDEEEEAAEERRSMRTIWVAG-KSLSAREAAALIVEEAKVILQQDLIEMGVQWGPHSPLSSSTHSLTSG-SEVKEHTFKSQTKSSHKRLASKSRNSMRVSGSNGKQSPEAGQGLDECRERPDSL-CKFQ-GNHEIQTPSVYRARKRTSLGVNKEMLRTSLKEGKPSTKEVLQTLSFEKTRKAALSFSSEQANNSFPSGRDRKYRKKSWGSSPMSDSVMHRDDLQGQTMCKSTLCEDPQKSLEEQNTEYRSPGLFAKNVSFCAKEKCNKTSFPLQMQQPCLRRKPES-GAAVDHSVAVSQNKNVVEQPPGAPRDRRGLAAHGRAEVNEVLTENGTESQ-----LHDTHPVSQCLENHSEKQTNTCTRQKTLTEG----QAGISHVTRGSNDLTPIRCERLKLNSKEHDSNPCPQALGTNAGR----TEAPQSSEALGQAGGQCENLLNSPGIQEKTSAHATNKTEHSHVANQ--AFCDFGDSLYLDTQSEEIIEQMATKNATQGAE----AAGITEEGSATQNEPHSTTGGQHIP--------GAANTDHVDRKNTESVKENPEKN-IDRRTPHSLIFHSPTPQGGNSACFKENEHSVTDSQLNSFLQGLETQD--KPIIPLAPQMRTSTGVEEESL--PETSLNMSDSILFDSFGEDSFGQRQSLDVKAKQPLLSEMTPNHFHNPPYPQEDPVMTPHMSEPQGTLERMACLSGES-IIFSEIDSAQVIEALDNMAAFYMQENCNPITLKT-EPRDLAALGNECPQGEVVRGEQHEGSSKPKFMEINQDNSFTWSAASFNLSPELQRILDKVSTPRENEEPELMHADLSCFEENSTESHERQDMNSDLGT--VQRTSFLPSNGVKSRTEGLESKAKHGGASSALPHK--AAADDNGLIPPTPLPASASASASKLALPEILGTSVKHQKAS--------CLFDSPSDNQNQDLSQELRDSLKDSDGSVVDTSFFLQ-SQDGLLLTQASCSSESLAIIDVASDQILFQTFVKEWQCQKRFSISLACEKMTSSTSSKTATIGGRLKQVNSPQEASVEDDGFPVHGSDCAVVVGLAVCWGGKDAYYLSLQKEQKQSEMSPSLAPPPLDATLTVKERMEYLQSCLQKKSDQERSVVTYDFIQTYKVLLLSCGISLEPSYEDPKVACWLLDPDSKEPTLHSIVTSFLPHELALLEGIETGPGIQSLG-LNVNTDHSGRYRASVESVLIFNSMN---QLNSMLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECETQKHIMQAKLDAIETQAYQLAGHSFSFTSADDIAQVLFLELKLPPNGEMKTQGGRKTLGSTRRGTESDRKLRLGRRFSTSKDILNKLKDLHPLPGLILEWRRISNAITKVVFPLQREKHLNPFLRMERIYPVSQSHTATGRITFTEPNIQNVPRD-FEIKMPTLVRESPPSQASGKGQLAMAR-QNQKVYGLHPGQRTVLEKTS-DRGVPFSVSMRHAFVPFP-GGLILAADYSQLELRILAHLSRDCRLIQVLNSGA--DVFRSIAAEWKMIEPDAVGDNLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYKGINHFMRDTVKNCRRDGFVETILGRRRYLPGIKDNNPYHKAHAERQAINTTVQGSAADIVKVATVNIQKQLETFHPTFKSHGHRESMLQSDRAGLLPKRKVKGMFCPMRGGFFILQLHDELLYEVAEEDVVQVAQIVKNEMEC-------AIKLSVKLKVKVKIGASWGELKDFDV----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGS6-1", "uniprot_id": "DPOLQ_MOUSE", "id": "Q8CGS6-1", "name": "DNA polymerase theta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLPRRSRKRRRS------------SSGSD--TFSGDG-DSFVSPQLRCG----------PVLSPPPG-----LGRGRRLTGTGTNKRRVSDDQIDQLLLANWGLPKAVLEKYHSFGVRKMFEWQAECLLLG-HVLEGKNLVYSAPTSAGKTLVAELLILKRVLETRKKALFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQFSSLDIAVCTIERANGLVNRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVTRKSASHQAESASTLSNAVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKIGNSIYDSSMKLVREFQPLLQVKG----DEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGFIRVLAATSTLSSGVNLPARRVIIRTPIFSGQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGSLEPVHSCLQRQG--EVTASMIRAILEIIVGGVASTSQDMQTYAACTFLAAAIQEGKQGMQRNQ-DDAQLGAIDACVTWLLENEFIQVAEPGDGTGGKVYHPTHLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTP--VFEDWISIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIHKRFFTSLVLLDLISEIPLKDINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLIRVSLLNAQRARFLYASGFLTVADLARADSAEVEVALKNSLPFKSARKAVDEEEEAAEERRSMRTIWVTG-KGLSAREAAALIVEEAKMILQQDLIEMGVRWDPKSPLSSSTHSRTST-SEVKEHTFKSQTKSSHKRLASMGRNSIRASGSNDKPSPDAERGIDDCSEHADSL-CKFQ-GNFEPQTPSICTARKRTSLGINKEMLRKSLKEGKPSTKEVLQTFSSEKTRKTALSFSSEQVNNTLPSGRDRKYQKKSWGSSPVRDSGMHRGDLQGQTMCTSALCEDSQKSLEEQNAEFRSPGLFAKHLPSCAKEKCKKPSLPLQRQQACSRRSTES-CAAVGHPAAGS--------SPAAARDRRGLAARETEKGNEALTENGGESQ-----LQDTYPVSQYLEYHSEKHTNTCTRQKTLTEG----QAGSSYVARDSNDAAPIKCERMKLNSKDRDSNPCRQALGSYTGR----TEALQSTAKLGQAGGQCENLLNSSGVQGKTGAHATNRTEHSHASNP--AFCDFGDSLDLDTQSEEIIEQMATENTMQGAK----AVVIMEEGSAMQNKCHSTPGDQHVP--------GAANTDHVDSKKVESVKANTEKN-INRGAPVSLIFHT---QGENGACFKGNEHSVTDSQLNSFLQGFETQEIVKPIIPLAPQMRTPTGVEEESL--PETSLNMSDSILFDSFGEDGFGQGQSPDIKANQPLLSEMTPNHFSNPPHPQEDPVMTPTVSEPQGTQQQGVCLSGES-IIFSDIDSAQVIEALDNMAAFHVQENCNSVALKTLEPSDSAVLGNECPQGKLVRGDQNEGSPKPKLTETNQDNSFTWSGASFNLSPELQRILDKVSSPRENEKPKMIHVNLSSFEGNSKESHEREEINSDLGT--VQRTSVFPSNEVKNRTEGLESKARHGGASSPLPRKESAAADDNGLIPPTPVP----ASASKVAFPEILGTSVKRQKASSALQPGESCLFGSPSDNQNQDLSQELRDSLKDYDGSVADTSFFLQ-SQDGLLLTQASCSSESLAIIDVASDQILFQTFVKEWQCQKRFSISLACEKMTSSMSSKTATIGGKLKQVSLPQEATVEDAGFPVRGCDGAVVVGLAVCWGAKDAYYLSLQKEQKQSEISPSLAPPPLDATLTVKERMECLQSCLQKKSDRERSVVTYDFIQTYKVLLLSCGISLEPSYEDPKVACWLLDPDSKEPTLHSIVTSFLPHELALLEGMETGPGIQSLG-LNVNTEHSGRYRASVESVLIFNSMN---QLNSLLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECESQKHVMQAKLDAIETQAYQLAGHSFSFTSADDIAQVLFLELKLPPNGEMKTQGSKKTLGSTRRGNESGRRMRLGRQFSTSKDILNKLKGLHPLPGLILEWRRISNAITKVVFPLQREKHLNPLLRMERIYPVSQSHTATGRITFTEPNIQNVPRD-FEIKMPTLVRESPPSQAP-KGRFPMAIGQDKKVYGLHPGHRTQMEEKASDRGVPFSVSMRHAFVPFP-GGLILAADYSQLELRILAHLSRDCRLIQVLNTGA--DVFRSIAAEWKMIEPDAVGDDLRQHAKQICYGIIYGMGAKSLGEQMGIKENDAASYIDSFKSRYKGINHFMRDTVKNCRKNGFVETILGRRRYLPGIKDDNPYHKAHAERQAINTTVQGSAADIVKIATVNIQKQLETFRSTFKSHGHRESMLQNDRTGLLPKRKLKGMFCPMRGGFFILQLHDELLYEVAEEDVVQVAQIVKNEMEC-------AIKLSVKLKVKVKIGASWGELKDFDV----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75417-1", "uniprot_id": "DPOLQ_HUMAN", "id": "O75417-1", "name": "DNA polymerase theta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLLRRSGKRRRS------------ESGSD--SFSGSGGDSSASPQFLSG----------SVLSPPPG-----LGRCLKAAAAGECKPTVPDYERDKLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLG-QVLEGKNLVYSAPTSAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNAVQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVREFEPMLQVKG----DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDTVGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQDMHTYAACTFLAASMKEGKQGIQRNQ-ESVQLGAIEACVMWLLENEFIQSTEASDGTEGKVYHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTP--MFEDWTTIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVEVEVILKNAVPFKSARKAVDEEEEAVEERRNMRTIWVTGRKGLTEREAAALIVEEARMILQQDLVEMGVQWNPCALLHSSTCSLTHSESEVKEHTFISQTKSSYKKLTSKNKSNTIFSDSYIKHSPNIVQDLNKSREHTSSFNCNFQNGNQEHQTCSIFRARKRASLDINKEKPGASQNEGKTSDKKVVQTFS-QKTKKAPLNFNSEKMSRSFRSWKRRKHLKRSRDSSPLKDSGACRIHLQGQTLSNPSLCEDP-FTLDEKKTEFRNSGPFAKNVSLSGKEKDNKTSFPLQIKQNCSWNITLTNDNFVEHIVTGSQSKNVTCQATSVVSEKGRGVAVEAEKINEVLIQNGSKNQNVYMKHHDIHPINQYLRKQSHEQTSTITKQKNIIERQMPCEAVSSYINRDSN--VTINCERIKLNTEENKPS-HFQALGDDISRTVIPSEVLPSAGAFSKSEGQHENFLNISRLQEKTGTYTTNKTKNNHVSDLGLVLCDFEDSFYLDTQSEKIIQQMATENAKLGAKDTNLAAGIMQKSLVQQNSMNSFQKECHIPFPAEQHPLGATKIDHLDLKTVGTMKQSSDSHGVDILTPESPIFHSPILLEENGLFLKKNEVSVTDSQLNSFLQGYQTQETVKPVILLIPQKRTPTGVEGECLPVPETSLNMSDSLLFDSFSDDYLVKEQLPDMQMKEPLPSEVTSNHFSDSLCLQEDLIKKSNVNENQDTHQQLTCSNDES-IIFSEMDSVQMVEALDNVDIFPVQEKNHTVVSPRALELSDPVLD-EHHQGDQDGGDQDERAEKSKLTGTRQNHSFIWSGASFDLSPGLQRILDKVSSPLENEKLKSMTINFSSLNRKNTELNEEQEVISNLETKQVQGISFSSNNEVKSKIEMLENNANHDETSSLLPRKESNIVDDNGLIPPTPIP----TSASKLTFPGILETPVNPWKTNNVLQPGESYLFGSPSDIKNHDLSPGSRNGFKD-NSPISDTSFSLQLSQDGLQLTPASSSSESLSIIDVASDQNLFQTFIKEWRCKKRFSISLACEKIRSLTSSKTATIGSRFKQASSPQEIPIRDDGFPIKGCDDTLVVGLAVCWGGRDAYYFSLQKEQKHSEISASLVPPSLDPSLTLKDRMWYLQSCLRKESDKECSVVIYDFIQSYKILLLSCGISLEQSYEDPKVACWLLDPDSQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLG-LNAGSEHSGRYRASVESILIFNSMN---QLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLPPNREMKNQGSKKTLGSTRRGIDNGRKLRLGRQFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQSHTATGRITFTEPNIQNVPRD-FEIKMPTLVGESPPSQAVGKGLLPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFP-GGSILAADYSQLELRILAHLSHDRRLIQVLNTGA--DVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDQTGLSRKRKLQGMFCPIRGGFFILQLHDELLYEVAEEDVVQVAQIVKNEMES-------AVKLSVKLKVKVKIGASWGELKDFDV----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4P4-1", "uniprot_id": "F1Q4P4_DANRE", "id": "F1Q4P4-1", "name": "DNA polymerase theta", "aln": "MMTATTRKIYLGQHRIVKTRGLSLADEKPGQRQLSNLCQEDVSENRSIIAPKQIQSKQWMPGDSSLAMDEEILQAIDELGPEVMKFKKIEKIQQTEPAPLKKNCDFPKNAEIPKEQNAENISPSSPSEHKRTRTQAKKEGDWKDLAQKLLFSETKKIEVGGRTHDLKQNRDYSSPQKILNSMKKTSKVAKSKQKLNFREVTSPNDSKDYILFSPTHMAAAKERSVLQQQKRSLKNQSVSVLTPPPGLDLTVLGDATLSDAAQSIHMGRPADQLDKLLLSSWGLPKPVLEKYQSLGVHRMFEWQAECLTLG-KVLEGQNLVYSAPTSAGKTLVSELLILKRVLETRQKAMFILPFVSVAREKMFYLQNVFQEAGIRVEGYMGSTSAAGGFSALDVAVCTIEKANGLVNRLIEEDKLDLLGTVVVDELHMVGDSGRGYLLELLLTKIRYIAQKTATRNSGQSTSTG--VQIIGMSATLPNLDLLARWLSAELYSTNYRPVPLMEWVKIGTNIYDGSLNLVRQFTPALPIKG----DDDHIVSLCFETVQDGHSALLFCPSKNWCEKLADSIGREFYNLHHK--EMQSGSGGQSISLNQEGLLDVLAQLKRTPAGLDHVLQRTVPWGVAFHHAGLTFDERDILEGAFRQGYIRVLAATSTLSSGVNLPARRVIIRTPVFNGHLLDILTYKQMVGRAGRKGVDTIGESVLVCKEAERAKGMSLIQGSLKPISSCLVKREGEGVTTSMLRAILEIIVGGVASSPQDVRMYAACTLLAASIAAEEVHQDGSESEARNKGAIEACIEWLMDNEFIHIQKEGDVER---YCPTHLGSATLSSSLSPPEALGIFADLQRAMKGFVLENDLHILYQITP--VYVDWTTIDWYQFFCLWEQLPSAMKRVAEMVGIQEGFLARSVGGKLIAKTEKQRRQMAIHKRFFTTLVLLDLVSEEPLGAVAKKYGCSRGQLQSLQQSASTYAGMVTVFCNRLGWHNLELLLSQFQSRLSFGVQRELCDLVRISLLTAQRARTLYSSGFVTVAELARADVTEVEKALRKAIPFKSSRQAVDESEVEAQERKSMRCIWVSGKKALTEREAAQQIVAEAQLLLQKDLALLGVEWNP-ACLPAKTQPDNSSNTEPRSMSGGTEHEGGQDLMLNVTEEKLLLENNSNNNSHPPLRPLESTTNLEKTMDVDSGVSSAECQPDKKCELQSSVLHKVLKSIN--AKDKGCDNNQTVESSSESLQRRNSCLNTCISGNDQHCVSPVSKRRRMDAAG------------DEEGPTVTGVKMRIAN--GLATDRKEMPKP-----------EELCRIDQVKMKLN-----------------------------KDTGLKKDSRSCTPLPNEEVTNVCVVSSGKGK------------------------KRTSKMKHLNIN-----------------------ADINHETQTEKEEMVAEIYGKFSNR--------------DQNEG---DLHVNTRVKNDLVCNSEKLSSPDLYTNG---LEEFGDSFQLDTQTEKMLHGHDFSHRNVELN--------VVRENKQDNQVDSTS-------------------EKVVKQSSFLEKENRVSKEQNKGPFESLSLHDN---GWPTEAKPKYNISLTDSQLENILN-YSNQVPEEEQCANKPAEQRENNESSDHV--TDNSFNRSSSFLFDSLYDNSILDAMEEAAIDQDNKGDQEAEVKVNSNGSSPE---LIPERREALPTDDQEAIQWGESSFNLSEWGDSLIIG--------------EQYLEKISKACDGPRLGAEKPSYTDDIVSELNVSQSNEYQQKVERHRLNSS--SFHISPGMQDLFDKWSD------------QFSTVPDATAHSNSLVEPN----------AVVLEEAVSLTKTKEIEKEGPEVSRSEDFVTVQAKKVTPSDLVPPTQVLEP-VTPRVKMTTSAIQSPKNVTKQRSE--------LDPNIKSCTQRYHQPCLRTNSTSVLGAPLADEGLTRLSQCPSLPASNSCSPETFSIIDVASDRRLFETFVNEWKTKERFSLAVACEKTDSTSVQPETVIGGKFKKPTTPMRNKRKD-GFLLKGYEDLVVIGISVSWGAKDAYFVSLQQELVDTDISASLAPPPLDDTLTVEERLKQIQSCLQKDSS---VTVTYDFIHLYKILLLACELAVRGTFEDPKIACWLLDSSSKERTLHNMVTSFATEDLPMLEGISAGQGVQSLG-IYGEASQPGRYRAAIESVLVFRVMT---QLNCLLEKDGFLDVFKKVEMPTQYCLALLELNGIGFSIAECEAQKHVMQAKLSALESQAYQLAGHSFSLTSPEDVAEVLFLELKLPPNGDLNGLKNKKTLGYTRR---AGARIKLSKQFSTTKDVLEKLKPLHPLPGVILEWRRITNALTKVVFPLQREKKWHSHLKMDRIHPISQSHTATGRVSFTEPNIQNVPKD-FEIQMPTLIEE---SQTSQNGGSKMWCKRTKINRLLAP--LLKVSDKSPDKGMQFSVSMRHAFVPFS-GGLILAVDYSQLELRILAHLSRDRRLLHVLNSGA--DVFKSIAAEWKMVDPASVDDNMRQQAKQICYGIIYGMGAKSLGEQMGIEENDAACYIETFKSRYNGIQNFLRETVQKCGKNGYVKTLLGRKRFLPGIKDSNVYIKSHAERQAVNTTVQGSAADIVKLATINIQRRIEEAFPGVPTSHQHPSIRLGG--------RHRNQFRPLRGGYFILQLHDELIYEVAEEDVIQVAQIVKREMES-------VVKLYVKLRVKVKVGPSWGNLQDLDI----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18475-1", "uniprot_id": "DPOLQ_DROME", "id": "O18475-1", "name": "DNA polymerase theta", "aln": "-----------------------------------------------------------MAFSQSFNFGNSTLMALEKG----MQADDKENAQPGNGNIQVQSAGNEVNSEIQEINSEFFRDEFSYEVNQAHKPAEQSVVNVSQVQQHMAVVSNQDSEDQSRSSALNDQICTQSSFEGEDAGADAVLDQPNLDENSFLCPAQDEEASEQLKEDILHSHSVLAKQEFYQEIS----QVTQNLSSMSPNQLRVSPNSSRIREAMPERPAMPLDLNTLRSISAWNLPMSIQAEYKKKGVVDMFDWQVECLSKPRLLFEHCNLVYSAPTSAGKTLVSEILMLKTVLERGKKVLLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLHVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRNG-----------LQIQVITMSATLENVQLLQSWLDAELYITNYRPVALKEMIKVGTVIYDHRLKLVRDVAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRLRTN---LNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIRSPLFGGKQMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSELQPITSCLDMDG----STHLKRALLEVISSGVANTKEDIDFFVNCTLLSAQKAFHAKEKPPDE--ESDANYINDALDFLVEYEFVRLQR-NEERETAVYVATRLGAACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMWEKLSSPMKKVGELVGVRDAFLYKALRG----QTKLDYKQMQIHKRFYIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTFAGIVTAFCNSLQWSTLALIVSQFKDRLFFGIHRDLIDLMRIPDLSQKRARALFDAGITSLVELAGADPVELEKVLYNSISFDSAKQHDHENADEAAKRNVVRNFYITGKAGMTVSEAAKLLIGEARQFVQHEIGLGTIKWTQTQAGVEIASRAIHDGGEVDLHMSLEEEQPPVKRKLSIEEN-----------------------------------GTANSQKNPRLETVVDTQRGYKVDKNIANQSKMNPNLKEIDAQNKARRNSTAHMDNLNPISNDPCQN----------------------NVNVKTAQPIISNLNDIQ----------------------------------------------------------------------------------------------------------------------------KQGSQIEKMKIN--------------------------------------------------------------------PATVVCSPQLANEEKPSTSQSARRKLVNEG--------------MAERRRVALMKIQQRTQKEN-------------------------------------------QSKDQPIQASRSNQLSSPVNRTP--------------------------------------------------------------------------ANRWTQSENPNNEMNNSQLPRRNPRNQSPVPNANRTASRKVSNAEEDLFMADDSFMLNTGLAAALTAAES---------------------------------KIASCTEADVIPSSQPKEPEVIGALTPHASRLKRSDQLRSQ------------------------------------------------------------------RIQSPSPTPQREIEIDLESKNESNGVSSMEISDMSMENPLMKNPLHLN---------------------------------------------------------------------ASHIMSCSKVDETASSFSSIDIIDVCGHRNAFQAAIIEINNATRLGFSVGLQAQAGKQKPLIGSNLLINQVAAAENREAAARERVLFQVDDTNFISGVSFCLADNVAYYWNMQIDERAAYQG---VPTPLKVQELCNLMARKDLTLVMHDGKEQLKMLRKAIPQLKR---------ISAKLEDAKVANWLLQPD-KTVNFLNMCQTFAPECTGLANLCGSGRGYSSYG-LDTSSAILPRIRTAIESCVTLHILQGQTENLSRIGNGDLLKFFHDIEMPIQLTLCQMELVGFPAQKQRLQQLYQRMVAVMKKVETKIYEQHGSRFNLGSSQAVAKVLGLHRKAKG------------------------------RVTTSRQVLEKLN--SPISHLILGYRKLSGLLAKSIQPLMEC------CQADRIHGQSITYTATGRISMTEPNLQNVAKE-FSIQVG---------------------------------------------SDVVHISCRSPFMPTDESRCLLSADFCQLEMRILAHMSQDKALLEVMKSSQ--DLFIAIAAHWNKIEESEVTQDLRNSTKQVCYGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRDYTTRVVNFARSKGFVETITGRRRYLENINSDVEHLKNQAERQAVNSTIQGSAADIAKNAILKMEKNIERYREKLALGDN--------------------------SVDLVMHLHDELIFEVPTGKAKKIAKVLSLTMEN-------CVKLSVPLKVKLRIGRSWGEFKEVSV----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7Z5Q5-1", "uniprot_id": "DPOLN_HUMAN", "id": "Q7Z5Q5-1", "name": "DNA polymerase nu", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENYEALVGFDLCNTPLSSVAQKIMSAMHSGDLVDS------KTWGKSTETMEVINKSSVKYSVQLEDRKTQSPEKKDLKSLRSQTSRGSAKLSPQSFSVRLTDQLSADQKQKSISSLTLSSCLIPQYNQEASVLQKKGHKRKHFLMENINNENKGSIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKRKHITYN----------------------------------------------------------------------------------------------------------------NLSEKTSKQMALEEDTDDAEG------------------------------------------------------------------------------------------------------------------------------------------------------------------YLNSGNSGALKKHFCDIRHLDDWAKSQLIEMLKQAAALVITVMYTDG----------------------------------------STQLGADQTPVSSVRG-----------------------------------------------------------------------------------------------IVVLVKRQAEGGHGCPDAPACGPVLEG---------------------------------------------------------------------------------------FVSDDPCIYIQIEHSAIWDQ---------EQEAHQQFARNVLFQTMKCKCP---------------------------VICFNAKDFVRIVLQFFGNDGSWKHVADFIG----------------------------------------------------------------LDPRIAAWLIDPSDATPSFEDLVEKYCEKSITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYG-------------LWQLFRTLELPLIPILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLKLHLLSQRNSLP----------------RTGLQKYPSTSEAVLNALRDLHPLPKIILEYRQVHKIKSTFVDGLLACMK-----KGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIQITTPKNFKG--------------------------------------KEDKILTISPRAMFVSSK-GHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQWKDVPVEQVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKDFARAAIAQCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAMIHVFTAVAASHT--------------------------------LTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQALELQLQVPLKVSLSAGRSWGHLVPLQEAWGPPPGPCRTESPSNSLAAPGSPASTQPPPLHFSPSFCL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::: : *.: . . : :. :: * : . . :* .:: :. : . . . . :* * :: . : : : ::. . : : . . : : : .. .. : : : : . :. : . : . . . .. : : .. * . ::. : : . : . : . . . : : *.::* **::.. .: .: .: . : . . . * ::: :. : ..* :*:* *. :* .: . . : : * :. :* : : * * : * : : ::* . * :*:. :*: *. *:. :** :*:: :. : * . . : *.***:: ..**:*.:.:. :.* . . :* * *:. . :*:.*:.*:*:***:*:* * *:.::: . *:* ::::.*: : * . *: :*:: *.::** * . *. :. ::* : * . *. *..: .: . * * :: **:* * *: : :*****:* :******: * * ::: : :: ::****::** . : * :: ** ::* * *:*.: * ***.: .. ", "identical_positions": 106, "similar_positions": 247, "identity": "3.69%" }, { "cls_id": "homologset.agr.FB:FBgn0002906", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88700-1", "uniprot_id": "BLM_MOUSE", "id": "O88700-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPLNNLQEQLQRHSARKLNNQPSLSKPKSLGFTFKKKT-SEGDVSVTSVSVVKTPALSDKDVNVSEA--FSFTESPLHKPKQQAKIEGFFKHFPGRQQSKG-TCSEPSLPATVQTAQDTLCTTPKTPTAKKLP--VAVFKKLEFSSSADSLS---DWADMDDFDMSAS-DAFASLAKNP-ATRVSTAQKMKKTKRNFFKPPPRKANAVKTDLTPPSPECLQVDLTKESEEEEEEEEEAEGADCLSRDVICIDNDSASEELTEKDTQESQSLKAHLGAERGDSEKKSHEDEAVFHSVQNTEYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKGILSTSEELLSKPEEMTTHKSDAGTSKDCDAQQIR-IQQQLIHVMEHICKLVDTVPTDELEALN--CGTELLQQRNIRRKLLAEAGFNGN----DVRLLGSLWR----HRPDSLDNTVQGDSCPVGHPNKELNSPYLLSHSPSTEE--------CLPT---TTPGKTGFSATPKNLFERPLLNSHLQKSFVS-SNWAETPRMEN----------RNESTDFPGSVLTSTTVKAQSKQAASGWNVERHGQASYD---------------------------IDNFNIDDFDDDDDDDDWENIMHNFPASKSSTATYPPIKEGGPVKSLSERISSAKAKFLPVVSTAQNTNLSESIQNCSDK-LAQNLSSKNPKHEHFQSLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTKETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKYPDVSCDNCCKTK--DYKTKDVTDDVKNIIRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVKSG------IFGKGTTYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSIKKQK--------ALVAK-VSQREEVVKKCLGELTEVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVIPVLQKYSEWTVPAEDGSPGA-----RGAPEDTEEE-EEEAP---------VSSHYFANQTRNERKRKKMSATHKPKRRRTSYGG-FRAKGGSTTCRKTTSKSKFYG--VTGSRSASCASQATS--SASRKLGIMAPPKP--VNRTFLRPSYAFS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQW1-1", "uniprot_id": "D3ZQW1_RAT", "id": "D3ZQW1-1", "name": "RecQ-like DNA helicase BLM", "aln": "--MFGSPVGWIMAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKT-PEG-----DVSVVRTPVLSDKDVNMSEA--LSYTEPPLHKPKQQSNIDGFFKNSPGGQQSKE-TCSELSLPEVVQIPQDASCTTPKTPAVKKPH--VAIFKKLEFSSSADSLS---DWADIDDFDVPAS-DAFVSLTRNP-TTRVSTAKKLSSSKRNFFKPPPR-ASAVKADLTPSSPECLQVDLTKEQEEE---------ADCLSRDVICIDTDPASEELLEKDVQEGLSLDARLGTERVDSAKKSHEDKAAFQSPQNALYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKDILSTSKDLS-KPEEMTTPKSDLGTNEDCDAQQTS-LQQQLIRVMEHICKLVDTVPIDELKALT--CGDKLLQQRDIRRKLLAEAGFNRN----DVNLLGSLWR----HRPDSLDNTVQCDSCPVGHPGKELNSPYLPSHSLSTEE--------CLPT---TASGKTGFSATPKSLSERPPLNSHLQKSFVS-SNWAETPRTES----------RTESTYFPGSVLTSTTVKDESKHVASGRDIEREVQASYD---------------------------IDNFNIDDFDDDDDDD-WENIMHNFSVSKSSTAAYPPIKEGGPVKSLSERISSAKAKFLPVASTAQNKNLSESIQNCSDK-FAQNLSSKNPKHEHFQSLNFPHTKEMMKIFRKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQRFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVALDCLEWIRKHHPYDSGIIYCLSRKECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVVHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTRETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKHPDVSCDNCCKTK--DYKTKDVTDDVKNIVRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSVKKQK--------AAVAH-VSQRDEAVMKCLGELADVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEIIPVLQKYAEWTLPAEGGSPGS-----RGSRRSTPEETEEEEA---------VSSHYFANQTRNERKRKKVSASQKPKRRRTSYGGGFRAKGGSTTCRKPSSKSKFSG--VTGSRSASCASQATS--AASRKLGIMAPPKP--VNRPFLRPAYAFS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54132-1", "uniprot_id": "BLM_HUMAN", "id": "P54132-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTED--FSFSEP-LPNTTNQQRVKDFFKNAPAGQETQR-GGSKSLLPDFLQTPKEVVCTTQNTPTVKKSR--DTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSH-FVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDD---------SEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQIS-LQQQLIHVMEHICKLIDTIPDDKLKLLD--CGNELLQQRNIRRKLLTEVDFNKS----DASLLGSLWR----YRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGD--------CLLT---TTLGKTGFSATRKNLFERPLFNTHLQKSFVS-SNWAETPRLGK----------KNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYD---------------------------IDNFDIDDFDDD---DDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDK-SAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTK--DYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQK--------ALVAK-VSQREEMVKKCLGELTEVCKSLGKVFGVHYFN-IFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP---------VSSHYFASKTRNERKRKKMPASQRSKRRKTASSG-SKAKGGSATCRKISSKTKSSS--IIGSSSASHTSQATS--GANSKLGIMAPPKP--INRPFLKPSYAFS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUA3-1", "uniprot_id": "A0A8M6YUA3_DANRE", "id": "A0A8M6YUA3-1", "name": "RecQ-like DNA helicase BLM", "aln": "MTNERASCKYAMSSLPQNNLKEHLERHNN-AAQNKLSLLKPKPGGFCFKKKSSSGISKVEVPQKVTGSSVLANRSVNIPSN--FEVTKNPVTFSQKPERVAPKVNFFTAPSKPKTNTVNPLANPFALNKTPLVQSTIKALPKSAALPKDSTNDQTVELKHDISQLS-FNEWDDLDDFETPVKSRVASPVAGTS-TKKPSVSDQNTSSSCSSKCEETKVNEESQATETITAPKDVLSAANGVSTET---------AEREPEDSPIKKSKRPKKSVQHTALLSDTEDEEIIHCVSPDTNQKNFKSVAVAEKDKWGEPNVIDSDDCEENNHYEGFEDFIPPSPIPEEIS-----LSVSDKEK--SSSEPVTPANKKESSRSASGLPAPLDQSAKGLKGADDALFSVMESICCLVDTIPEHELIALT--CGTELLLQRAHRKRILAKGGSSRTSHSDSVSTPGFLNRPTFGVTPSNLTSLTPVTSGKREGVKTGFSFRKSIASVMSVGDESVFEDSDCIINGVETPGGTWNPNSSTKISAGRDTFNGSIQTLSKPESKTDKCYSRLS----------FNESSNQTDLFYSPKRVDSGSRNADSSVEINIAGSSSLRTGAEPVDD-----------------FLLDDFDIDDFDENDIPDYYEEPPSVLESRNNSGVKTPSVQEGGSSKSFER------KTFTPPAPKSIKTPNPEPLY-------------RNPAHDRFRGFNFPHSPEMMKIFHKKFGLHQFRFNQLEAINASLLGEDTFVLMPTGGGKSLCYQLPACVSAG----VTVVISPLRSLIVDQVQKLTTLDICATSLSGDKKDSEAARIYMQLSRKDPAIKLLYATPEKVCASGRMISALQNLYERGLLARLVIDEAHCVSQWGHDFRPDYKRLHELRRMFPNVPIMALTATATPRVQKDILNQLAMTRPQVFTMSFNRNNLKYSVLPKKPKKVDEECIQWIKKYYPRDSGIVYCLSRNDCDTLADSLQRAGIAALAYHAGLSDSDREYVQNKWINQDGCQVMCATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKRLIAMDKDGNQQSKATHINNLHSMVHFCENVAECRRIQLLAYFGEHTFNTSFCKEHPEVICDNCARPN--KYKSRNVTDDVKKIARFVQDNCEKVGNRYG-KSAQQNRLTLNMLVEIFLGSKSARIQTG------MFGVGAAYSKHNAERLFKKLVLDNVLMEDLYITNSGQAVAYISAGPKAMSVLNGCMQVEFHETESASSIRKHR--------ASVCEKVSKREEMVKKCLGELNDLCKKLGKVFGIHYYN-IFSTATLKKIAETLSADPEVLLQIDGVTEDKLEKYGAEFIELLQKYSEWQLPAEAQAESSGWIDTTRGHQNDEDDNDDDDEG-----GGDVTSTYFRSNSGRGAKRKQGSYSRKPKRRKGSSGQNSSAKGGYSSNWSSSRGGGRGGGYRGGSRGAGRGSRSAPSGSAAKRPGFMSLPTPQAAARPFLKPSFSHL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGI8-1", "uniprot_id": "BLM_DROME", "id": "Q9VGI8-1", "name": "RecQ-like DNA helicase Blm", "aln": "------MSKKPVAQRKQLTLSSFIGLDGNSQSQPKSRAASVRSKPPAVYNPIFLDASSSDDETTEISSQSNNGTIATKKSS--RDPRTAKLKKHTYLDLSVSPLAKLSAKKYARDSPKKPTSLDLSVSPLAELLAKKSDRDSPKKPVQNENSYTYRGLSESPVENKSIGDTLRKPPQKERKTSIVWLSDSPEK-KVTQNERKILDSPLQRFSFEDFPNKENGNRHHLLTLPDSPPPPQPVKKPEK---------TMWQNETKTIQDKDSPANPLVSNNLASISTLLDSSRAPNTYKGSSRNLFEDSPEKSGSGE-QGYKLGSAKENEIPTKPATASLERNSVTSSPSPAAPLKPRYSVAFDNSLADYLKDLAQNDNFSIDPNKQNTETLKSTLGFFRNTYVELMEKYCSLIDQIPAMHFNEIAGFQPNTFLKLKVMRQKFKARTQLVQNSLDKKESQLKAEQEALEKEEIEMQAEQAQQTVLSSSSPEKSRPIMPLPKVQEIKDEK--IPNRNQLIHDLCGEPDNFSPPSSPRDTQLIPKRQQLINDLCGEPDDFSPPSKQNDPHLLRKCEELVHDLCEEPDDYLAQSMMLDGDLEEEQLNGPTQGTTTSGMDDDEDDLEGLLAEIEDEHQKMQGRRSEFNGYSYKELEAVKVKEKHKETPINISLDDDGFPEYDEAMFEQMHSQAAANKSRVSSAGPSTSKSVVPTKQTSALHSQKLSGNFHANVHNDGITGEFDGQKFEHSTRLMHGLSYSFGLKSFRPNQLQVINATLLGNDCFVLMPTGGGKSLCYQLPAILTEG----VTIVISPLKSLIFDQINKLASLDICAKSLSGEQKMADVMAIYRDLESQPPMVKLLYVTPEKISSSARFQDTLDTLNSNNYISRFVIDEAHCVSQWGHDFRPDYKKLGVLKKRFPNVPTIALTATATPRVRLDILAQLNLKNCKWFLSSFNRSNLRYRVLPKKGVSTLDDISRYIRSKPQHFSGIIYCLSRKECDETSKKMCKDGVRAVSYHAGLTDTDRESRQKDWLTG-KMRVICATVAFGMGIDKPDVRFVLHYSLPKSIEGYYQEAGRAGRDGDVADCILYYNYSDMLRIKKMLDSDKALQYNVKKIHVDNLYRIVGYCENLTDCRRAQQLDYFGEH-FTSEQCLENRETACDNCINKR--AYKAVDALEHARKAARAVKDLCSG-----------RSRFTLLHIADVLKGSKIKKIIDFNHHKTPHHGVLKDWDKNDVHRLLRKMVIDGFLREDLIFTN-DFPQAYLYLGNNISKLMEGTPNFEFAVTKNAKEAKAAVGSVSDGATSSTADGQSGMREIHERCYTDLLDLCRTIASQRNVTMAS-IMNIQALKSMAETLPITEKDMCSIPHVTKANFDKYGAKLLEITSNYASEKLLMQAVLDEEEEQAAAKQRPSTSGWNNESVDW-----DMAVASQGNANTSG-ASGFNSFRAGKRKKIYKSGASKRYKTSTTSPAARKTTSARGRGG--RAGAKRAESSASSAS--------GWKSKKTGNSFGFDLMPLPGSK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35187-1", "uniprot_id": "SGS1_YEAST", "id": "P35187-1", "name": "ATP-dependent helicase SGS1", "aln": "-----------MVTKPSHNLRREHKWLKETATLQEDKDFVFQAIQKHIANKRPKTNSPPTTPSKDECGPGTTNFITSIPASGPTNTATKQHEVMQTLSNDTEWLSYTATSNQYADVPMVDIPASTSVVSNPRTPNGSKTHNFNTFRPHMASSLVENDSSRNLGSRNNNKSVIDNSSIGKQLENDIKLEVIRLQGSLIMALKEQSKLLLQKCSIIESTSLSEDAKRLQLSRDIRPQLSNMSIRIDS--------LEKEIIKAKKDGMSKDQSKGRSQVSSQDDNIISSILPSPLEYNTSSRNSNLTSTTATTVTKALAITGAKQNITNNTGKNSNNDSNNDDLIQVLDDEDDIDCDPPVILKEGAP-HSPAFPHLHMTSEEQDELTRRRNMRSREPVNYRIPDRDDPFDYVMGKSLRDDYPDVE--REEDELTMEAEDDAHSSYMTTRDEEKEENELLNQSDFDFVVNDDLDPTQDTDYHDNMDVSANIQESSQEGDTRSTITLSQN-------KNVQVILSSPTAQSVPSNGQNQIGVEHIDLLEDDLEKDAILDDSMSFSFG-------------RQHMPMSHSDLELIDSEKENEDFEEDNNNNGIEYLS-----------------------------DSDLERFDEER--ENRTQVADIQELDNDLKIITERKLTGDNEHPPPSWSPKIKREKSSVSQKDEEDDFDDDFS-------LSDIVSKSNLSSKTNGPTYPWSDEVLYRLHEVFKLPGFRPNQLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFING--LLDLVYISPEMISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIHNLELKEPVFLKQSFNRTNLYYEVN-KKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQAD-EIQVICATVAFGMGIDKPDVRFVYHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKHLNKLQQVMAYCDNVTDCRRKLVLSYFNED-FDSKLCHKN----CDNCRNSANVINEERDVTEPAKKIVKLVESIQNE-------------RVTIIYCQDVFKGSRSSKIVQANHDTLEEHGIGKSMQKSEIERIFFHLITIRVLQEYSIMNNSGFASSYVKVGPNAKKLLTGKMEIKMQFTISAPNSRPSTSSSFQANEDNIPVIAQKSTTIGGNVAANPPRFISAKEHLRSYTYGGSTMGSSHPITLKNTSDLRSTQELNNLRMTYERLRELSLNLGNRMVPPVGNFMPDSILKKMAAILPMNDSAFATLGTVEDKYRRRFKYFKATIADLSKKRSSEDHEKYDTILNDEFVNRAAASSNGIAQSTGTKSKFFGANLNEAKENEQIINQIRQSQLPKNTTSSKSGTRSISKSSKKSANGRRGFRNYRGHYRGRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : : . : . . .. . . . . : . . . . . . . . : : . . .. . . . :. . . : ::. . : * . : . . : . :. : : : . : . . . . . :: : : .. . . . : .. . . .: : .:: : * * ** ***:.:**:* *:* *:**************** :. * .*:***** **: **:::* . :* *. ::. . : : : :.*:* :** :.:* : ::. * ::*:*:*******:****** ***.: ::: :*.:* :******. :*: **: :* : . : **** ** * * ** .. : ::. :**:** *:..*: : : : *: . ****: * *: * :*:***:************:* * ::*:::******:*******: : *: ::.: *: :: :: :* : . : *.::* :: :*:*:::*** * **.*. * .. * : **** . : :. : .:. : *:. . *.*: ::: **: :: .* .: : .*:: ::: .* * :. . . :*: * : .:: * :..: * .: . : . . : . . . :. .: :: . :* .: : . :. . ::. ::. : . . : . . :. . . . . . :. : . : ", "identical_positions": 171, "similar_positions": 292, "identity": "11.04%" }, { "cls_id": "homologset.agr.FB:FBgn0002909", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LU18-1", "uniprot_id": "F1LU18_RAT", "id": "F1LU18-1", "name": "Structure-specific endonuclease subunit SLX4", "aln": "-------------------------------------------MDESDDDFKELCASFFQRVKKNATKEASGERTRRKASG-HTQERGKRKEASQAVARSKALQGPSEKKPRLGSQTSRTKKQRAPKSQEGDPALPVNGKGGVLAPTPDQPVLCERPQSTQTENA----------------------PNGDSTTTGMPSPSKPRASELVLQRMKQFKRADPERLRHTSEESPLKTAPGESVPRSLQQEIVAGNEYKPKLHNTDSDAAMALALQQEFRKEEASSRPDSLEEKGLFFCQICQKNLSAMNVTRREQHVNRCLDEAEKALR------PAPPQIPDCPICGKQFLTAKSRISHLKRCAVRMEVGPQLLLQAVRLQTAQPEAGSSPQVPSFSNHVGDLKRKGTTNKREPQRRWKVSKPEAPSEDLLVAMALSRSEMEHCPVVPPLR----------LENAYSEKKGPGAEK---KSRRKRPPVCPPQLVTQDSETTSRQIEDRVAQLLSEETELACTPPLPASKISKEEREHASWRVRQPEGRRGFLWELSALTG--AWVKESFYTVGLLPPLVSQCPPK----EPELPLELPKQQEPSTQRPPASQSSLPVSHSPKSQLLSSSQREGQALQDLVDLAVEGLSSSPCSRSAGMP-----TGLDLVPSSLPLTGFVLPCQ-KTLRKDDSVALSLGLLATDFGAMVNNPHLSDVQFQLDSGEVLYAHKFVLYARCPLLIQCVNTEGFSAVEDGD-LTQRVLLSDVSSEAAHAFLNYLYTADTDVPPSLAPDLRSLALRFGVSDLVELCEQVPATADS-------EGE-QPE-HSEDCESRAENFQALLRSVWGNEEEEAETLLKPEVCEE------------DREKVNEAEMDEIYEFAATQRKLLQGERAAATDGNTNQHGEDSPVSEPSLAGVQKDRQLENTEQMAS-GLEREE-----VHEGD---SIPLQDQCPDWAGKAEAQDALEEAVDHP--------------GFCSPSDSLQETGKECLPLHPAQAHDCKQLLPS--NQRASLELSQVTVGHEEQSDRVRERQANMA------QAPSPHPCCLPSQSSVGDSPSQSWLHLYHTSSLSPSVSQSH--ISKVVSPSSPSPVTPAKQRRDSNILTLR------KEAGHHKGRQNSSKLGRRSRSILISPAKSPPIDLTQSVPEPLSPRAQDPLRRVKKEGEVILLLDSDEEWELEHIKTESVSKDSP-GGKIPEVSPRPSDLLSVIDVEGDQEHFPSPPKR----EAGLQQEEEGQLG---------DRPAPGHRHIPWLFCSQTPSLGEDSATESSWLVPATPGASKSRDRSSQ-TQIRSLKIRTPSGETAQQTPRP-----PVLEAAQKFSVIMPHTQP------------VTVGASDTRRQAYRSPSRPYLRRHKLSSSQPSCPVP----DFTSWCQKSSSPRPCPPNPPAADEVVEVGDSDDEQEVASHQ--ENSSPVLDGDPPGPMGDYCWH-EPLSPIPIDHLNLERTGPLITSSPGSQVQEALQSDGWHSPG---LGTTPIRGSCGALRESQEQSSQAGSPESSKLSVLSQALWDDWDEEEGHSPEAPPVAQMLSAR-TRKPDRPETPKGANQRKNLPPKVPVTPMPRYSIMETPVLKRELDRFGVRALPKRQMVLKLKEIFQYTHQTLESDSEDEIQSSQVPPGVARSQASNTETCNPSRSGSYTQLKATAGLRTQRSKGPSKRKSLQHQEEQLGESISHPSRSPAGEPSRPDGDAQLPASQECMATSVDGSDNSFSSQSSS-GEFGAALESVGEDKDEEDGVTASQVAMQ-APDTEEAVRRYICSQPALHRKVLMYQPLQLAELQAELKQNGIPVAMGKLLDILDAQCVTFTTAAARKEKLRQKRR------QPSGRKKKDQK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1D7-1", "uniprot_id": "SLX4_MOUSE", "id": "Q6P1D7-1", "name": "Structure-specific endonuclease subunit SLX4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MVPESAPNGNSQPLP-----------------------------------------SCFTTTGVPSPSKPRVSELVLQRMKQFKRADPERLRHASEESPQKTALGDDVPRSPPEETVGENEYK--LDATDSDAAMALALQQEFRREEASSHHDSLEEKGLFFCQMCQKNLSAMNVTRREQHVNRCLDEAEKAQR------PASPRIPDCPICGKPFLTTKSRISHLKQCAVRMEVGPQLLLQAVRLQTAQPEVDGSPQVPSFSNNVGGLKRKGVTTKREP-RRRKVNKPEAPSEDLLVAMALSRSEVEHCPVVPPLR----------LENAFSEKIRLGAEK---KSRKKRPPVCPPQLVTQDSETTGRQIEDRVAQLLSEEAELSCTPPLLASKISKEELEPAGWRARLPEGKRNFLWELSALTG--AWAEESFYTVGLFPPIVSQCPSK----EPQLPLELPKQGEPSPRRPPASQSSLPVSHSPKIRLLSSSQRERQALQDLVDLAVEGLSSSPQPGSRGVP-----TGLDLVPSSLPLTGFVLPCK-KTLKKDDSASLSLGLLVTDFGAMVNNPHLSDVQFQLDSGEVLYAHKFVLYARCPLLIQYVSTESFSSEEDGD-LTQRALLSDVSSEAAHAFLNYLYMADTDMPPSLVPDLRSLALRFGVSDLVQLCEQVPAVVDL-------EGE-QPEETSEDCESRAETFLELLRSVWVDNEEEVETLLKPELCEE------------ERERVNEAEMEEIYEFAATQRKLLQWGRAADPDGSTNPHGEDGAVSEPSLAGVQSNRQLENTEHMESSGLEKEEALASWEQEGH---STPLQDQCPDWAGKAEAQDALGEATDDP--------------SFCSR----HRRGKECLPLHPNKAHGCKQPLPS--NPRVSSELSQITVDHEEQSDHVRETQADMA------QAPTPHSCSLVSQSSVDGSPSQSWLHLYHTSHLSPSVSQSHSSISRVASPRSLSPTTPTKQRRGSNIVTLR------KDAGHHRGQQSSPIAGHRNRGILISPAKSPPIDLTQSVPEPLSPRAQDPLHFVKKEDEVILLLDSDE--ELEHTKTESVSKDSPEGRKVPEFSPRSSELFSVIDVEEDHEHFQSPLKR----EAGLQHGEEGQLG---------NQSALGCRDIPWLLCSQKTSLDEDSATDTSWLVPATPGVSRSRDCSSQ-TQIKSLKTRIPSDETAQQTPRPNLERRTMLETAQQFSVIMPHTQP------------ITLGAFDSGRQAYRSPSHPYPRHHRLSSSQPSCPGP----DFTRWSQKSSAPRPCLPNLPAADDVVEVGDSDDE--VASHQ--GNSSPVLDGDPPGPMGDYCWN-EPLSPIPIDHLNLERTGPLTTSSPSSQVLEALHSDDCHSPG---LGTTPIRGSCGTLRESQERSSLAGSPE---------ALWDDWNEEEGQSPEAPPVAQMLSTR-TRKPDRPETPKGANQKKNLPPKVPITPMPRYSIMETPVLKKELDRFGVRALPKRQMVLKLKEIFQYTHQTLESDSEDEVQSPQIPAELPCRQASTTETCNPSR-------------------------------------------LPTGEPSHPDGDAQLPASQESMATSVDGSDNSFSSKSSS-AEFGAAFEYSDEDKDEEVGVTASQAAIQ-AADTEEAVRRYIRSKPALHRQVLRYQPVELAELQAELKQNGIPVAMGKLSDILDAQCITFTTAAARKEKLKHKRR------QPSGRKKKDQK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY92-1", "uniprot_id": "SLX4_HUMAN", "id": "Q8IY92-1", "name": "Structure-specific endonuclease subunit SLX4", "aln": "MKLSVNEAQLGFYLGSLSHLSACPGIDPRSSEDQPESLKTGQMMDESDEDFKELCASFFQRVKKHGIKEVSGERKTQKAASNGTQIRSKLKRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDPPVLRETAQNTQTGNQQEPSPNLSREKTRENVPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKGLFFCQICQKNLSAMNVTRREQHVNRCLDEAEKTLR------PSVPQIPECPICGKPFLTLKSRTSHLKQCAVKMEVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKRRGPTSKKEPRKRRKVD--EAPSEDLLVAMALSRSEMEPGAAVPALR----------LESAFSERIRPEAEN---KSRKKKPPVSPPLLLVQDSETTGRQIEDRVALLLSEEVELSSTPPLPASRILKEGWERAGQCPPPPERKQSFLWEGSALTG--AWAMEDFYTARLVPPLVPQRPAQGLMQEPVPPLVPPEHSELSERRSPALHGTPTAGCGSRGPSPSASQREHQALQDLVDLAREGLSASPWPGSGGLAGSEGTAGLDVVPGGLPLTGFVVPSQDKHPDRGGRTLLSLGLLVADFGAMVNNPHLSDVQFQTDSGEVLYAHKFVLYARCPLLIQYVNNEGFSAVEDGV-LTQRVLLGDVSTEAARTFLHYLYTADTGLPPGLSSELSSLAHRFGVSELVHLCEQVPIATDS-------EGKPWEEKEAENCESRAENFQELLRSMWADEEEEAETLLKSKDHEE------------DQENVNEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHS--------------SCSSPSRDCQAERKEGSLPHSDDAGDYEQLFSS--TQGEISEPSQITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGS----HHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLS------KEPGHQKGKERRSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRS----EAVLQQEDEGALPE--------NRGSLGRRGAPWLFCDRESSPSEASTTDTSWLVPATPLASRSRDCSSQ-TQISSLRSGLAVQAVTQHTPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCLTP--VSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQ--ANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGL--LDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGE-VSASQAAVQ-AADTDEALRCYIRSKPALYQKVLLYQPFELRELQAELRQNGLRVSSRRLLDFLDTHCITFTTAATRREKLQGRRR------QPRGKKKVERN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RN23-1", "uniprot_id": "A0A8M1RN23_DANRE", "id": "A0A8M1RN23-1", "name": "Structure-specific endonuclease subunit SLX4", "aln": "-------------------------------------------MDDSDQDFKDLCSRLLKRVRRKGPAESGDEKR----------------------------SATKDEEPSSPSSGRNPPKRRKRTKDAVKTQLNGRSQTAVSAGAP---------------------------------------------QADSGVSATGKVKDAVIRRMQQFKRASPERLLHAETDGNCDAPDGVQHTEDVS-----------------GDEALALRLQQELDR-EARAAAGDVEDGGLFFCQLCQKDLSSMSPSLRTQHINRCLDASESSAPSTSHHSQPRPRVPECPICGKSFKSEKSRSAHLKRCSSDMGVKPNDLLQALRRQAAETESDRN---ADQTQQVGGAVRRDGVPVKKKSRRKGQKLDEDTMMALALSRSLLEQEVEKKRELEEQREILAQISSPPAATAPVLKWKPGAGKGRGKRRKGASPVQPPLLLIQDPQIALNRLQERVSSLLLCSRPPSPPTPTLSPSS-------------LPLQPHAPLWDKSALHRGRQNSVSEFYTSELSSFIQPWVAPVK--ENDKPLEATPVKSTPGLLQDKPSDQSPTQNRTTRPLTPCSDTPGTQALQDLMELAEEGMTLTQYGYTAYTAAVG-TSDKDNPLNELPSSGSAPEAT----DRKTDKTVYISKLASDLSSMVNNPQLSDVQLQVDSGDVFFAHSFMLYTRCPLLANMVHDSGFGVQEEGLPVARRVLFGDVLGEAVLAFLQYLYTAHCPLTHTLIPHVQELADRFGLAELQQQCEEYSGSTDENASKDMFQAPKPHFRDQEEHKFAESNFLELLQSMWQHENSEEEDEFNETSGEERVMEEVQERDGEKEERVDEEELDEIYEFAATQRKTETMLETATETEDDEGDANTFPENEMMKDEAVEKGESESLQEKSAGSCHSNSRGVDGTESAMVTSPTETPNLETARVCLMPDLDAGTHENKDPDASLDKSYDRLFSQSIGEYREPSQAPASCSQKQHYKASHTLQRNTPAPFRPSCVSEVIDLSVSPPLSSGMSGETSFPMPG-VSPVPYKDEDTCLRKDILSCPGIENPPSPPKSHSKQVELIVLSDDSNEGMDVDGKHNTSTTKCALTPKSPIKSLPEPPHIVKSCALQVKPTETGPQGHAGKHVNTSKQVTIDTETMSDSSERCSPGVANESVFDGSAEVSWLIPATPVPSTRCSSAQTCVTMRRTQLFPKPCSASSSSSSSSVLDSLKPATFASSSSKCSKEKQAPLSELQSGQSSSKEHTSTEMDHSPGFQRPLQHLRLSQVASDVSRASTIMGHLAQGVPQPSSSTPVHSVGSLQRKILFDSPVDREYEVPLRDSRGLSSSFNCQKKVESLQLNSPSPSKTPEKSQHGCFKPSHQESSPERSRESGNNGIEQMKVGEESLNQSVEEVVDISRKSLSDMDDPWRRAREDNPKQSVEEVVHIADNSLCNIEEKVEEENPNQSVEEVVKMVGSSFCQMDEPPIAFDDS-WGLDGGIGSQKPHFSLRLDSSEGTLSSPGLESKGQMTSLQIKSPVASRAHNKTPDASPPSFNPSLPDPDMWDDWEEEGEEVP--LPLSQRLAAPSDKQVAELKTPVAP-RKRNNGPLVPITPMPGFSDMETPELKNRLNRFGVRPLPKKQMVLKLKEIHQYTHQLQSSESEDETSGPRRPPIASSSKSLS-----------------------------------------------------FKQPTAPPAVSPVKLPPREEEETLSASQNSNTSSTAESERSNPELCLSEDEDSDTEGITASQAVVR-EKDKLLAVRQFILSDPELYSRVLQYQPLPLAELRASLRAAGIRLAAAKLLDFLDSQCITFSTAKQGKSTTSRRKRRVKTTTAGRGRKKTTRPNGGVA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS48-1", "uniprot_id": "SLX4_DROME", "id": "Q9VS48-1", "name": "Structure-specific endonuclease subunit SLX4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRKTRRANFKNLQPRLTRSTKAAADTLSLSNFFATPENAEEVPS----------------------CLADIPVQPDPPAPKIKPIRTSNVFEKPGPKPKKAPKLKASTVSTSSGARRG--------------------RGKSKQQPSISNFLRNEQIFAEVTAQHCMADNFSADDIEMALALSKSESEKHGRLRLHDDDDAVVDLLDDEEKSTERIRHKLQKYGFRTAAKEDYKSLAVLPVVASKG------------------------------------GRRGKWANRFTSLTLRNPDVQQKKLEEKVSALLGQEMRGK-----------------------EPNGEDCCLTPYTVITA-------------------------------ALKELRAEGESRILREPSEGPIDDLESYYVTDLFEVSRTPAHHLLKNWAAIQGRDFSPERET-----------------------------------QKCRQLRQQHELVYAELERYYGDPQKLEEEVMQELDELEKLVADNMIEDDSVVINIVEAESSSTGSSPS-----------------------KEPPDKRPKMTMEDKENLQPTTSKASLTVPAQSTRCTSPD---------------------------------LFADSEDEPDIVTTAISNEP--------------EDVRNLSMKVYKNVSISERSSSVAEIEIVSSNDEPSQITTYEVFSSDEVKTVSNATQEKIS------------------------------FDDDFIDLTQEFDMVEFNESKP----------------------------------------------------RTPNLIASSETDSNVDNLNGDTILDFS------------------------------------------------------SQEVSCPISKELYAKYAKVETFP----------------VWNAAAEEEDKIEFSLSMERDLKSSEQSSHQLG------------------ILTTPNDTEHSSSFSELNFSRNSLRRSVSLSTDLSFKSPLNWKMNSSAEKRVSPAAS------------------------------------PYKQSDASVDLTQNSDDENDAILLSDEEINYSIWKGNK--TVKDLDIGDDSSDSCFASPVTKKRAIPQFQTEEDLDAFLMDFST-----------------DGNGSQGSHSPNKSALSKERAEFG--------------------------------------ILDAAPSQPFSLSELQSHADKEKSSDNEINWAEASFLDAPAKPLSRRSSHKFNELLAKISKPAHNSGDDFDE----------FDQMVFQSTKEAASSAGETSDMP-------------------QGLDLLLKGEIKTTAIPETRAPGNQTPIEPQQVDVDGNVYSVRVCHTPKPDFATLPESEILQQLYKYGIKPLKRKQAVKMLEFIYNQTHPIMKTAAVQDLPARSEPIVRSKS------------------------------------------------------TPVIMERPHSQVAKSTSKTLKAIGTKKDLTFNDATGEELLRFSQSLAPSLCDDFETFVMQTNVTKKTPQPLVPLHIAWHNLICANPQLHESVLTYEPIDLQAVYLHLKHMGHRYDPKDLKTFFDRRCIIFRYELGAPGKQAERHVR------RHTKKPSKRK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *: : .:* .: * :. . . :.: : : . . .*. * : : . *::. : :: : : * .: : . : : . . .: : *: . ::.* . : . .. :: . . : :: . *: . . * ::.: .:::::*: ** . * * :.: . . . : : *:: : ..:: : : ::: .:*: : :. : .:: : .:: : * .. . .. . . . .* . :.* .:. :: ..:.* : . * * * : .:. :.: ::*. . . . :. . : .. : : .. : .. . . : :: : . .. .. . : : : . . . *. . . . : . : . . * . .: . : :... : . . : :.... : . . : . . . : .: *:. ..* . . . . . . : : : : :. . * ** * :: : . : ..* ::*::.* ::* * *: *.: ** .: : :: . . . . . . . : .. :.. . : . ..:: . : * : * :.* *: ** *:*. * : *: * * ::* :*: * . :: :* : ", "identical_positions": 59, "similar_positions": 294, "identity": "3.05%" }, { "cls_id": "homologset.agr.FB:FBgn0002914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06876-1", "uniprot_id": "MYB_MOUSE", "id": "P06876-1", "name": "Transcriptional activator Myb", "aln": "-----------------------MARRPRHSIYSSDEDDEDIEMCDHDYDGLLPKSGKRHLGKTR----------------------------------------WTREEDEKLKKLVEQNGTDDWKVIANYLPN--RTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKK--TSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVATSFQKNNHLMGFGHASPPSQLSPSGQSSVNSEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHGDSAPVSCLGEHHATPSLPADPGSLPEES-ASPARCMI--VHQGTILDNVKNLLEFAETLQFIDS-------------------------------------------------------------------------------------------------------------------------------FLNTSSNHESSGLDAPTLPSTPLIGHKL---TPCR-DQTVKTQKENSIFRTPAIKR----SILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQESG------PPLLKKIKQEVESPTEKSGNFFCSNHWAENS--LSTQLFSQASPV-----ADAPNILTSSVLMTPVSEDEDN-------------VLKAFTVPKNR-----------PLVGPLQPCSGAWEP--------ASCGKTEDQMTASGPARKYVNAFSARTLVM------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2A4-1", "uniprot_id": "A0A0G2K2A4_RAT", "id": "A0A0G2K2A4-1", "name": "Transcriptional activator Myb", "aln": "-----------------------MARRPRHSIYSSDEDDEDIEMCDHDYDGLLPKSGKRHLGKTR----------------------------------------WTREEDEKLKKLVEQNGTDDWKVIANYLPN--RTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKK--TSWTEDEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVVSSFQKNNHLMGFAHASPP----PTSQSSVNGEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHGDSAPVSCLGENHATPSLPADPGSLPEES-ASPARCMI--VHQGTILDNVKNLLEFAETLQFIDSD----SSRCDLSSFEFSEEAAAFSPSQ---------QHTGKTFQLQEREGHGTRSAGEPSLRVTRRVLSEASLRQAKASPLVFLRKRRGQASPTAAGDSSSSLFADVSS-STPKRSPVKSLPFSPSQFLNTSSNHENSGLDTPTLPSTPLIGHKL---TPCHRDQTVKTQKENSIFRTPAIKR----SILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHVVEDLQDVIKQESDESGIVAEFHENG------PPLLKKIKQEVDSPTEKAGNFFCSNHWEETN--LSTQLFAQASPV-----ADAPNILTSSVLMTPVSEDEDN-------------VLKAFTVPKNR-----------PLVGPLQPCVGAWEPT-------PSCGKTEDQMTASGQARKYVNTFSARTLVM------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10242-1", "uniprot_id": "MYB_HUMAN", "id": "P10242-1", "name": "Transcriptional activator Myb", "aln": "-----------------------MARRPRHSIYSSDEDDEDFEMCDHDYDGLLPKSGKRHLGKTR----------------------------------------WTREEDEKLKKLVEQNGTDDWKVIANYLPN--RTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKK--TSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEES-ASPARCMI--VHQGTILDNVKNLLEFAETLQFIDS-------------------------------------------------------------------------------------------------------------------------------FLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKR----SILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESDESGIVAEFQENG------PPLLKKIKQEVESPTDKSGNFFCSHHWEGDS--LNTQLFTQTSPV-----ADAPNILTSSVLMAPASEDEDN-------------VLKAFTVPKNR-----------SLASPLQPCSSTWEP--------ASCGKMEEQMTSSSQARKYVNAFSARTLVM------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51960-1", "uniprot_id": "MYBA_MOUSE", "id": "P51960-1", "name": "Myb-related protein A", "aln": "-----------------------MAKR-----SRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVK----------------------------------------WTRDEDDKLKKLVEQHGTDDWTLIASHLQN--RSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKK--SSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSS--KLQHK---------------PCATMDHLQTQNQFYIP--VQIPGYQYVSPDGNCVEHVQ----TSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVR-RKRLPPQ--PGSFSSWSGSFLMDDSMSN----TLNNLEEHTTEFYSMDENQTVSAQQ-NSPTKFLA--VEANAVLSSLQTIPEFPRTLELIES---DPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNSRNGGDSEAIPLTSPNVVKFSTPPTISRKKKRIRVGQSAGSELGSASLSEVGN-RRIKHTPVKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRR----SILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETG-TDIFLKEEDE--------PAYKSCKQEHSASVKKVRKSLALESWDKEE--PGTQLLTEDISD-----MQSENILTTSLLMIPLLEIHDNRCNLTPEKQDINSANKTYTLNKKRPNPNPC---KAVKLEKSLQSNCEWET--------VVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARW4-1", "uniprot_id": "A0A8I6ARW4_RAT", "id": "A0A8I6ARW4-1", "name": "", "aln": "-----------------------MAKR-----SRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVK----------------------------------------WTRDEDDKLKKLVEQHGTDDWTLIASHLQN--RSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKK--SSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSS--KLQHK---------------PCATMDHLQTQNQFYIP--VQIPGYQYVSPDGNCVEHVQ----TSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVR-RKRLPPQ--PGSFSSWSGSFLMDDSMSN----TLNNLEEHTTEFYSMDENQTVSAQQ-NSPTKFLA--VEANAVLSSLQTIPEFAETLELIES---DPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNSCNGGDSEAIPLASPNVVKFSTPPTILRKKKRLRVGQSAGSELGEGSLSEGNN-AALKHTPVKTLPFSPSQFFNTCPGSEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRTPTIRR----SILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETG-TDIFLKEEDE--------PAYKSCKQEHSASVKKVRKSLALESWDKEE--PGTQLLTEDISD-----MQSENILTTSLLMIPLLEIHDNRCNLTPEKQDINSANKTYTLTKKRPNPNTC---KAVKLEKSLQSNCEWET--------VVYGKTEDQLIMTEQARRYLSTYTAPSSTSRALIL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10243-1", "uniprot_id": "MYBA_HUMAN", "id": "P10243-1", "name": "Myb-related protein A", "aln": "-----------------------MAKR-----SRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVK----------------------------------------WTRDEDDKLKKLVEQHGTDDWTLIASHLQN--RSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKK--SSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSS--KLQHK---------------PCAAMDHMQTQNQFYIP--VQIPGYQYVSPEGNCIEHVQP---TSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVR-RKRIPSQ--PGSFSSWSGSFLMDDNMSN----TLNSLDEHTSEFYSMDENQPVSAQQ-NSPTKFLA--VEANAVLSSLQTIPEFAETLELIES---DPVAWSDVTSFDISDAAASPIKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNTCNGGNSEAVPLTSPNIAKFSTPPAILRKKRKMRVGHSPGSELRDGSLNDGGN-MALKHTPLKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITTPLHKETTPKDQKENVGFRTPTIRR----SILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETG-TDLFLKEEDE--------PAYKSCKQENTASGKKVRKSLVLDNWEKEE--SGTQLLTEDISD-----MQSENRFTTSLLMIPLLEIHDNRCNLIPEKQDINSTNKTYTLTKKKPNPNTS---KVVKLEKNLQSNCEWET--------VVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9R3-1", "uniprot_id": "A0A8M2B9R3_DANRE", "id": "A0A8M2B9R3-1", "name": "", "aln": "-----------------------MANMK----SRSEDEDEDRHSTDPDSREP--KNSKRTLCKIK----------------------------------------WSRDEDEKLKKLVEQQGTDNWKLIANYFPT--RTDGQCQHRWQKVLNPELVKGPWTKEEDQRVIELVHKYGPKRWSVIAKHLQGRIGKQCRERWHNHLNPEVKK--SSWTQEEDRIIYEAHKRLGNRWAEISKLLPGRTDNSIKNHWNSTMRRKVEHEGYLQEGNKSYNSDPGQKKRPK---------------SSPTVEYPHDQNQPILSGQSQPPRYPYRSQSAQCLENINV---RISSFVSPFHD-DPDKEKRIKELELLLMSAESEVR-RQSGPRN--PESYSSWSDSLPDDS---------VESVEDR-----GVEDGRSVSIPLPVSPSKFLA--AEASAVLSTLETIPEFAETMELIDSVSRDPLAWSDVTSFDLSESGPSPKPTNPADVC-----TETLAFPINAPTVQTMTRPCAAVSQGKSGTLPNTCMNRFSSPPTSICRKKRREGGDQSPAEERSCSYIDNSG-NSPKHTPVKGLPFSPSQFFNVS-GGEPLSLDNPALTSTPVCGQKCLLNTPHQKETTPKHQKENAGFRTPKLHK----NIVVHTPRTPTPFKNALAAQEKMHGPLRMVPQPLALLEEDIREVLKEETG-ADIFTQVQNQ--------LQYRSYEQ-MEAPARKVRKSLVLDSWEKDC--LNVQLFPQQQINNNGTTSQSDGLLTRSMLMMPLTEREENSCSPESLKDSLSVVCSVSPQGKRENMIQ-----RSPLYQTPTPANNEWDA--------VVFGKTEDQLIMTEQARRYLNP-NPTACISRALVL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48972-1", "uniprot_id": "MYBB_MOUSE", "id": "P48972-1", "name": "Myb-related protein B", "aln": "-----------------------MSRR------TRCEDLDELHYQDVDSDLLEQRDN---RCKVK----------------------------------------WTHEEDEQLRALVRQFGQQDWKFLASHFPN--RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPAESRDCKP-VYLLLELED--------------------KEQHQGVQPVDGQGSLVSSWPLVPSIVKEESSEEEIAIAATSAKELGHEPVPADLGEVRTPEPPESL-KREYQ-EFSSPETSLPYKWVVEAANLLIPAVGSS---------------LSEALDLIESDPDAWCDLSKFDL--PEEPSTEGSVVSSPVQPQTSQQQQ-----------EEALQSSQQAATPGPSV-------------TEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYPSSEVLPDQK-----YSMDNTPHTPTPFKNALEK----YGPLKPLPQTP-HLEEDLKEVLRSEAGMELIIEDDMRP--------EKQKRKPGLRRSPIKKVRKSLALDIMDEDG-----KLMSSTMPK---PLSLPTSVTPSSCGFTSPGSKEGNS-----------LLNQGFLQAKPEKVVAAQ--KTRSHIPTPAPMTHAWKT--------VACGGTKDQLFMQEKARQLLSRLKSSHTSRTLILS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKK8-1", "uniprot_id": "A0ABK0LKK8_RAT", "id": "A0ABK0LKK8-1", "name": "Myb-related protein B", "aln": "MMVVPVFERLRQENCQPELWRPCFKKK------KVGEELDELRYQDTDSDLLEQRDN---KCKVK----------------------------------------WTHEEDELLRALVRQFGQQDWKFLASHFPN--RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPNESRDCKP-VYLLLELED--------------------KDYQQNVQPVEGPGSLVSSWPLAPSTVKEEESSEEEAAVATTSKEHKQEPVPTDLGEVRTPEPLEFL-KREYQ-EESSPETSLPYKWVVEAANLLIPAVESS---------------LSEALDLIESDPDAWCDLSKFDL--PEEPSAEGSVNSSPVQLQTPQQQQQ----------HQQALSFHQAATPGPSV-------------TEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYP-SFVTPDQK-----YSMDNTPHTPTPFKNALEK----YGPLKPLPQTP-HLEEDLKEVLRSEAGIELIIEDDMRP--------EKQKRKPGLRRSPIKKVRKSLALDIVDEDG-----KMMSSTSPK---TLSLPTSVPSSSSGFILPGIKEDNS-----------LLNQGFLQAKPEKVVATQ--KPRSHIPAPAPMTRAWKT--------VACGGTKDQLFMQEKARQLLGRLKSSHTSRTLILS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10244-1", "uniprot_id": "MYBB_HUMAN", "id": "P10244-1", "name": "Myb-related protein B", "aln": "-----------------------MSRR------TRCEDLDELHYQDTDSDVPEQRDS---KCKVK----------------------------------------WTHEEDEQLRALVRQFGQQDWKFLASHFPN--RTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKK--SCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSESKDCKPPVYLLLELED--------------------KDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQ--EPIGTDLDAVRTPEPLEEFPKREDQ-EGSPPETSLPYKWVVEAANLLIPAVGSS---------------LSEALDLIESDPDAWCDLSKFDL--PEEPSAEDSINNSLVQLQASHQQQ--------------VLPPRQPSALVPSV-------------TEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKHA-AFVTPDQK-----YSMDNTPHTPTPFKNALEK----YGPLKPLPQTP-HLEEDLKEVLRSEAGIELIIEDDIRP--------EKQKRKPGLRRSPIKKVRKSLALDIVDEDV-----KLMMSTLPK---SLSLPTTAPSNSSSLTLSGIKEDNS-----------LLNQGFLQAKPEKAAVAQ--KPRSHFTTPAPMSSAWKT--------VACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ83-1", "uniprot_id": "A0AB32TZ83_DANRE", "id": "A0AB32TZ83-1", "name": "", "aln": "-----------------------MSWW------ARGEDEEEALCQDTDSDVADQRDCG--KVKVK----------------------------------------WTQEEDDKLRKLVLNVGSNDWKYIAGFLPN--RSEHQCQHRWFKVLDPDLVKGPWTKEEDEKVIELVKKYGNKQWAMVAKHLKGRLGKQCRERWHNHLNPDVKK--SSWTPDEDLIIYKAHRVLGNRWAEIAKLLPGRTDNAVKNHWNSTIKRKVETG-FYSG---VDTTLHVLQQTDP--------------------EELLSEEVEISCDG--------ASEELPVECSKREPEEKATAPPQK--------ASSPKTP-------KASTS-PKSEGGDSNVSTWVMDSSGFLSPSAAPT---------------LKEVMELMDGDLEGWCTMSDFDL--PEES-------------QSSELLQ-------------------------------------------FRLEGSALQELSKGSKGELIPISP----GG---ATPPSILSRRSRRRIALSP-----------DPNDSMTPKSTPVKILPFSPSQFLNMWTKQDTLDLENPSLTSTPVCSQKAVVTTPLHRDKTPLTQKENSLFITPNHK-----SDLDTMPRTPTPFKNAMEK----YGPLRPLPPTP-NLEEDLKEVLRSEAGIELIVEDEAPA--------EKKRKQ--VYRPPMKKVRKSLALDVIDCSESVAARKQQIKATVK---PSQKPQTVQPEPP-VSSCAVKEEN------------VLDQGFILGPNESGPASKPVLATPKTISPLPMSAAWET--------VVCGRTKDQLFMTEKARRYLRSLKSHTPNRALILS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04197-1", "uniprot_id": "MYB_DROME", "id": "P04197-1", "name": "Myb protein", "aln": "------------------MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHG-ENWEIIGPHFKD--RLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKK--TAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVE----------------------------------------RRSVNASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENADGASVTAVKGGDLAQESQDDHQK----------GSNLAHLSMQHLIKLTMPR--------------QTPIILKRTRKHIPETHHQAGCSS--SETFNQEEAAGNARSRPPSSPVISP---------------------------------------------------------------------------------------------------------------------IKSLPFSPSHFLKSPCLTTFEDMDLRASTPVTKVYNRVGMEIKKEMETSSIETPHKSQLGP----------------RTPTPFKKALAAIGKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSNSLTANNSKMMGAADQNSTLSTEYNAQSPPHMKRARKSLLSTWSSNHPYNAGSAKRIQPFET-----ETPSKFLTSPGDILKDTLCSEQD------------LPFDEGRKENRPFHNRRINKYRGGLTYDHVIDPKWAR--------VACGKSRDQMFMEEQAYACLKNLSCISRSLNFEKQKCLVNSFDRFGSL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22035-1", "uniprot_id": "BAS1_YEAST", "id": "P22035-1", "name": "Myb-like DNA-binding protein BAS1", "aln": "-------------------MSNISTKDIRKSKPKRGSGFDLLEVTESLGYQTHRKNGRNSWSKDDDNMLRSLVNESAKELG----------------------YENGLEDVKTIQQSNHLSKCIAWDVLATRFKHTVRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVLGPGSKGRLREWTLEEDLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVITKAIKENKNIDMTDGKLR------------QHPIADSDIRSDSTPNKEEQLQLSQQNNPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALPPLKEISAPPPIRMTQVGQTHTSGSIRSKVSLPIEGLSQMNK-------------QSPGGISDSPQTSLPPAFNPASLDEHMMNSNSISDSPKHAYSTVKTREPNSSSTQWKFTLKDGQGLSISNGTIDSTKLVK-----------ELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQANTLIPTNSTATNNEIIQGNVSANSMSPNFNGTNGKAPSSTASYTTSGSEMPPDVGPNRIAHFNYLPPTIRPHLGSSD------ATRGADLNKLLNPSPNSVRSNGSKTKKKEKRKSESSQHHSSSSVTTNKFNHIDQSEISRTTSRSDTPLRDEDGLDFWETLRSLATTNPNPPVEKSAENDGAKPQVVHQGIGSHTEDSSLGSHSGGYDFFNELLDKKADTLHNEAKKTSEHDMTSGGSTDNGSVLPLNPS---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :. .: :: * :. : * . : : ** *:*:* ** **::**: ::: .:.* :* :: : ** .** :*: : *.* * ** .** : . *.:* :*:. : *.. : :*:*.. : . . : . : . *:. :: : .. . . : .: :* :. . . . : : : : . . . . . . : . : : . ", "identical_positions": 35, "similar_positions": 91, "identity": "3.87%" }, { "cls_id": "homologset.agr.FB:FBgn0002917", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXR5-1", "uniprot_id": "NALCN_MOUSE", "id": "Q8BXR5-1", "name": "Sodium leak channel NALCN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTK-----PGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASN--YYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDT----CCLFRILPSTSSSSCDNPKKPTAEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQER-----RSLRHGSNSQRISRGKSLETLTQDHSNTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVDDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIIHSLRESQEQERSR--------------------------FLNPPSIETTQPSEDSNANSQD-------------------------------------------------------------HSMQPETSS-QQQLLSPTLSD----------------------------------------RGG---SRQDAADTGKPQRKIGQWRLPSAPKPISHSVSS------------------------VNLRFGGRTTMKTVVCKMN-------PMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q760-1", "uniprot_id": "NALCN_RAT", "id": "Q6Q760-1", "name": "Sodium leak channel NALCN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVIPVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTK-----PGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASN--YYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDT----CCLFRILPSTSSSSCDNPKRPTVEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPTKERSILSVQHHIRQER-----RSLRHGSNSQRISRGKSLETLTQDHSNTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIIHSLRESQQQELSR--------------------------FLNPPSIETTQPSEDTNANSQD-------------------------------------------------------------HNTQPESSS-QQQLLSPTLSD----------------------------------------RGG---SRQDAADTGKPQRKIGQWRLPSAPKPISHSVSS------------------------VNLRFGGRTTMKSVVCKMN-------PMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZF0-1", "uniprot_id": "NALCN_HUMAN", "id": "Q8IZF0-1", "name": "Sodium leak channel NALCN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTK-----PGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASN--YYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDT----CCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQER-----RSLRHGSNSQRISRGKSLETLTQDHSNTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIIHSLRESQQQELSR--------------------------FLNPPSIETTQPSEDTNANSQD-------------------------------------------------------------NSMQPETSS-QQQLLSPTLSD----------------------------------------RGG---SRQDAADAGKPQRKFGQWRLPSAPKPISHSVSS------------------------VNLRFGGRTTMKSVVCKMN-------PMTDAASCGSEVKKWWTRQLTVESDESGDDLLDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BF56-1", "uniprot_id": "A0A8M2BF56_DANRE", "id": "A0A8M2BF56-1", "name": "Sodium leak channel NALCN", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSAGAISALLFPLIHSLYSTASPSMLKRKQSSRVEAQPMTDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGIIKGENSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSPWGMLRIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFGTFNHHCVTNETE-----KEKVTWNSLAIPDTHCSPN-GEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQQLMRSSVFHMFILSMVAVDVIVAASN--YHRG-DHKLTNDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEDLDRFTTFPRAFMSMFQILTQEGWVDVMDQTLVAVGQMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDP----SCLFRRLPSASSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLMEKEITVNKILRACTRQRMLSGSFEGQPTKERSILSVQHHIRQER-----RSLRHGSTSQRISRGKSLETLTQDHSSTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRMIVRARFNASNTDPNTGAVNSTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMHVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWLPNNVPPESGAQLLMMLRCFRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFATFGVQLFAGKLAKCNDPHISSKDDCHGIFRINVSISKNLNLKLKDGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPENGGFRAKMYDITQHPFFKRGIAVLVLAQSVLLSVKWDELGAVTFPLATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRNRYDLLVTSLGLIWIILHFALQNAYTYMMGTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLIRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIILSLRESQQQDLRR--------------------------LLNPPSIETTVPSEDTNTHNQD-------------------------------------------------------------NPTQPEQNSGLQTLLSPTLSD----------------------------------------RSG---YRQDSAD--RPQRKLGQWRLP-----------------------------------------AGRTSVKSMVCKMN-------PVTDEASSGSEVKKWWTRQLTVESDESGDDLIDI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUW5-1", "uniprot_id": "A8JUW5_DROME", "id": "A8JUW5-1", "name": "Sodium leak channel NALCN", "aln": "MIDRLQIRRLGAAARNKRAGGGGGAGGGAVGSGGAGGGGGGGGAGAVPGAAGAAGTGPITGASATAASGSSGSGGHHQHHHHSHPYSTSGINTPATASTSSSSGNSLTPQQQQQQQHPHHQSHHGHHYAHHQQHTHHHAPPHSHHPHPHPHGHPHSYPHLRHSQPASASQFSFNPSPGSSPGNGLGLGARQDAASALNSPTTIVNSGSGSGGGSSVAFGMQPQQQQQSLAGGGGGGSSATAAPSSGGGHNNGAGLGPVVGGGGGGLNLLGGLGGMGGMGGGAAAAGMGICGGISSTVGSAAITGVPPIGLGIATGIGNKIMLGRKQSLKGGEPFLADYGPEESLNESADIEWVNKLWVRRLMRLCALVSLTSVSLNTPKTFERYPSLQFITFASDTAVTLLFTAEMIAKMHIRGVLHGEVPYLKDHWCQFDASMVSFLWISIILQIFEVLEIVPKFSYLSIMRAPRPLIMIRFLRVFLKFSMPKSRINQIFKRSSQQIYNVTLFFLFFMSLYGLLGVQFFGELKNHCVMNNTEYDLYKRPILTINSLAIPDTFCSMDPDSGYQCSPGMVCMKMD--FLSSYVIGFNGFEDIATSIFTVYQAASQEGWVFIMYRAIDSLPAWRAAFYFSTMIFFLAWLVKNVFIAVITETFNEIRVQFQQMWGARGHIQKTAASQILSGNDTG-WRLVTIDDNKHGGLAPETCHAILRSPYFRMLVMSVILANGIVTATMTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKIYCLGWRGYYKHSIHKFELLLAAGTTLHIVPMFYPSGLTYFQVLRVVRLIKASPMLEGFVYKIFGPGKKLGSLIIFTMCLLIISSSISMQLFCFLCDFTKFESFPEAFMSMFQILTQEAWVEVMDETMIRTSKTLTPLVAVYFILYHLFVTLIVLSLFVAVILDNLELDEDIKKLKQLKFREQSAEIKETLPFRLRIFEKFPDSPQMTILHRIPNDFMLPKVRESFMKHFVIELETEDSLVENCKRPMSECWESNVVFRKQKPVRIMNKTAKVRAAGSSLRKLAITHIINDSNNQRLMLGDSAMLPVVGTKGGGGLKSQGTITHSKPWRVDQKKFGSRSIRRSVRSGSIKLKQTYEHLMENGDIAAAPRANSGRARPHDLDIKLLQAKRQQAEMRRNQREEDLRENHPFFDTPLFLVPRESRFRKICQKIVHARYDARLKDPLTGKERKVQYKSLHNFLGLVTYLDWVMIFATTLSCISMMFETPNYRVMDHPTLQIAEYGFVIFMSLELALKILADGLFFTPKAYIKDVAAALDVFIYVVSTSFLCWMPLNIPTNSAAQLLMILRCVRPLRIFTLVPHMRKVVYELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLARCNDPTISRREDCVGVFMRRVFVTK-MKLTPGPDESYPAMLVPRVWANPRRFNFDNIGDAMLTLFEVLSFKGWLDVRDVLIKAVGPVHAVYIHIYIFLGCMIGLTLFVGVVIANYSENKGTALLTVDQRRWCDLKKRLKIAQPLHLPPRPDGRKIRAFTYDITQHIIFKRVIAVVVLINSMLLSITWIKGEVHTERLVIVSAVLTFVFVVEVVMKNIAFTPRGYWQSRRNRYDLLVTVAGVIWIILQTILRNDLSYFFGFMVVILRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMFLLVFFYALAGTILFGTVKYGEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMVQPPYCTLGNN-YWETDCGNFTASLIYFCTFYVIITYIVLNLLVAIIMENFSLFYSNEEDALLSYADIRNFQNTWNIVDIHQRGVIPVRRVKFILRLLKGRLECDPQKDRLLFKYMCYELDKLHNGEDVTFHDVINMLSYRSVDIRKALQLEELLAREEFEYLVEEEVAKMTIRTWLEGCLKKIRAQNASKQQNSLIAGLRATNEQPVMRPNIQEDKAPLGAVDKSAISTISGAVAGACPPTSDAFSPTFSSTENEEKDGSSSAVVQLPHSETSIAGTGSSATGAATATGTSSGLGVGPPTVQSTARHVMTVGKRGYALNRSDSTGSSAGRKFLAPTSSDPQQRSTLSDKERLHITSQQRKKNSMTTLPHAGQLGQLAKQRGGGGEATKSSSFFAQLNSEIGQFHYPTINAAAAAAALHGYGHGHGHGHGGHGGHGGHGEHQMHHHHGGALGSPSAMMSQMIGGSGKLLPFNNQANAVYEVHDWWQEQVLCP--QTSDDEI--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **** : ::*:**:*:*.:.*** *:** **: *:* **::*: .*.:*** ***:**.**::**: ** : :*:************:::*: .*:**:** **. ** **:*::**:**: ::* ::* .::* **.***** :*::::*.:*::**.:*:***.:**:.*::*:***: ***:****:** :. *** *:*: :* ********.** : .****. *: *:.:: ** :*:.**:::.*******:*:*******:*******:* **: *** *:**************** *** ***********:*. .**::*:: : :* *:**::* ** * ** : ::**. *:*:::*:: .: **:*: : * :.:* *:.** *:***:*:**:***: ** . *:**** **. *****: * :* * :************* ** **.***************::** .***: *:**:*:***: :: :* :**.************.**:***:*: ..: :*:**:********.***:*****************:******* * .*: **.**:*********: ***. : ::*.** :*::******:*: . : : * .*. . ::.. ** . : * : * . : :: ::: . : : *: * *.:. :: .: * :: **:*:. * *. :: * * :: . :. * *: .* :**::* *::****:*: :**:******:**.***:* ** ***::*: :*:**::* .** ** ...:*:.*:::************ .* ********:* ***. *****.** ******:** ***:********.* *:*....:*:***:** ****:* *:*.:*.*****:***.******.***:***** *: *****:*** **: **::**::****:.*:**:**** * ::** *:* .* ::* ::*. .*. *.: *********.*****:*:***:******:***::****:*: ***:*.:***:::******************:.*************** ***.**************:. :** ****** :*** **::** :*:***:.* * *. :*.*:**:**:**.** **::* *:************* *::*::*: * * :*::* *:::***:* ***.*****:*** **: ******.*****:: **:**.:*********.*.*:***.:. ..:::*:********************:** .: ** *****::.:*:***:*****:**:********:********.*** **** *:*:** **:** ::.****. ****:****:**** * :**:****:****:::**** *******:.***********:**********::** :****** *** **: ***:***: .:*. *:* .** :::* * **: :: *: .:. :.:. : :. .* : :*:** ** *.* :.:: : : ::**:: * .. : .:::.:* *. : *.. **:.** .*: ::.** : ", "identical_positions": 934, "similar_positions": 470, "identity": "41.66%" }, { "cls_id": "homologset.agr.FB:FBgn0002921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54708-1", "uniprot_id": "AT12A_RAT", "id": "P54708-1", "name": "Potassium-transporting ATPase alpha chain 2", "aln": "-MRRKT-EIYSVELNGTKDVKPADQRDDK----KFKGAKNKDLEPNKSHEKEELKKELDLDDHRLSNTELEQKYGTNIIQGLSSVRATELLARDGPNTLTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAFVIQY-VNN-SASLDNVYLGAILVLVVILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKVISAEQLVVGDVVEIKGGDQIPADIRLVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGRIASLASGVGSEKTPIAIEIEHFVHIVAGVAVSIDIIFFITAVCMKYYVLDAIIFLISIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSENQT-KQAFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRTVVGDASETALLKFSEVILGDVMGIRKRNHKVAEIPFNSTNKFQLSIHETEDPNNKRFLVVMKGAPERILEKCSTIMINGQEQPLDKSSADSFHTAYMELGGLGERVLGFCHLYLPAEQFPQSYIFDVDSVNFPTSNFCFVGLLSMIDPPRSTVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMELKDMTPEQLDELLTNYQEIVFARTSPQQKLIIVEGCQRQDAIVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAELCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRLVNTQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVAWETDDINDLEDSYGQEWTRYQRKYLEWTGSTAFFVAIMIQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIASQVIVALILSYGLGSVPALSFTMLRVQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1W8-1", "uniprot_id": "AT12A_MOUSE", "id": "Q9Z1W8-1", "name": "Potassium-transporting ATPase alpha chain 2", "aln": "-MRRKT-EIYSVELNGTKDVELADQKDDK----KFKGGKNKDSEPNKSQE-EELKKELDLDDHRLSNTDLEQKYGTNIIQGLSSIRAAELLARDGPNALTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAYVIQY-VSS-TASLDNVYLGAILVLVVILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKIIPAEQLVVGDVVEIKGGDQIPADIRLVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGRIASLASGVGSEKTPIAIEIEHFVHIVAAVAVSVGVIFFITAVCMKYYVLDAIIFLISIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSENQT-KQAFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRVVVGDASETALLKFSEVILGDVMDIRKRNHKVAEIPFNSTNKFQLSIHETEDPNDKRFLMVMKGAPERILEKCSTIMINGQEQPLDKSSADAFHTAYMELGGLGERVLGFCHLYLPADKFPQSYTFDVDSINFPTSNLCFVGLLSMIDPPRSTVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMELKDMTPEQLDELLINYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAELCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRLVNKQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVSWETDDINDLEDSYGQEWTRYQRKYLEWTGSTAFFVAIMVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIISQIIVALVLSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54707-1", "uniprot_id": "AT12A_HUMAN", "id": "P54707-1", "name": "Potassium-transporting ATPase alpha chain 2", "aln": "-MHQKTPEIYSVELSGTKDIVKTDKGDGKE---KYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQY-SSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHS-NQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06687-1", "uniprot_id": "AT1A3_RAT", "id": "P06687-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-3", "aln": "-------MGDKK-------------DDK---------SSPKKSKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDD-PSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PIC6-1", "uniprot_id": "AT1A3_MOUSE", "id": "Q6PIC6-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-3", "aln": "-------MGDKK-------------DDK---------SSPKKSKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDD-PSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13637-1", "uniprot_id": "AT1A3_HUMAN", "id": "P13637-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-3", "aln": "-------MGDKK-------------DDK---------DSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDD-PSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P271-1", "uniprot_id": "Q6P271_DANRE", "id": "Q6P271-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "-------MGYGRS-DSYRVATTQDNDDK---------ESPKKGKG--GKDLDDLKKEVPLTEHKMSIEEVCRKYNTDIVQGLTNARAAEYLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYAIQAATEDE-PAGDNLYLGIVLSAVVIITGCFSYFQEAKSSKIMESFKNMVPQQALVIREGEKLQINAEEVVGGDLVEVKGGDRIPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNIAFFSTNCVEGTARGIVVCTGDRTVMGRIATLTSGLETGKTPIAKEIEHFIHIITGVAVFLGVTFFILSIILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GASFDKSSGTWLALARVAALCNRAVFKAGQESLPILKRDVAGDASESALLKCIELSCGSVKAMRDKNKKVAEIPFNSTNKYQLSVHELDESEENHYLLVMKGAPERILDRCSTILQQGKEQPMDEELKEAFQNAYLELGGLGERVLGFCHLVMPGDKYPKGFAFDTDDINFQTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDLSQDQMDEVLKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLFFILVNIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPLRDKLVNERLISIAYGQIGMIQALGGFFSYFVILAENGFLPSVLVGIRLNWDDRSNNDLEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADVIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06685-1", "uniprot_id": "AT1A1_RAT", "id": "P06685-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-1", "aln": "-------MGKGVGRDKYEPAAVSEHGDK---------KSKKAKKE---RDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTPARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIRSATEEE-PPNDDLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEDVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAEEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQS-GVSFDKTSATWFALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEVCCGSVMEMREKYTKIVEIPFNSTNKYQLSIHKNPNASEPKHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDEVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDAKACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRETWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMGAALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDN2-1", "uniprot_id": "AT1A1_MOUSE", "id": "Q8VDN2-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-1", "aln": "-------MGKGVGRDKYEPAAVSEHGDK---------KGKKAKKE---RDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTPARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIRSATEEE-PPNDDLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEDVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAEEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQS-GVSFDKTSATWFALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEVCCGSVMEMREKYSKIVEIPFNSTNKYQLSIHKNPNASEPKHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDAKACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRETWDDRWVNDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMGAALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05023-1", "uniprot_id": "AT1A1_HUMAN", "id": "P05023-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-1", "aln": "-------MGKGVGRDKYEPAAVSEQGDK---------KGKKGKKD---RDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEE-PQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQS-GVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06686-1", "uniprot_id": "AT1A2_RAT", "id": "P06686-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-2", "aln": "-------MGRGAGREYSPAATTAENGG-----------GKKKQKE---KELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGALLCFLAYGILAAMEDE-PSNDNLYLGIVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGQTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS-HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PIE5-1", "uniprot_id": "AT1A2_MOUSE", "id": "Q6PIE5-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-2", "aln": "-------MGRGAGREYSPAATTAENGG-----------GKKKQKE---KELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGALLCFLAYGILAAMEDE-PSNDNLYLGIVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGQTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS-HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50993-1", "uniprot_id": "AT1A2_HUMAN", "id": "P50993-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-2", "aln": "-------MGRGAGREYSPAATTAENGG-----------GKKKQKE---KELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDE-PSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQS-GATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS-HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64541-1", "uniprot_id": "AT1A4_RAT", "id": "Q64541-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-4", "aln": "-MEPGKETAATSE----QKPRPTLRASN---------TNRQPKVKRRKKDLEELKKEVVMDDHKLTLDELSAKYSVDLTKGLSVTDAQEILTLNGPNVLTPPPTTPEWIKFCKQLFGGFSLLLWTGSLLCFLAYGIHVSYYQENANKDNLYLGIVLSAVVIITGCFSYYQEAKSSKIMESFKTMVPQQALVIRDGEKMQINVRDVVLGDLVEVKGGDQVPADIRVIAAQGCKVDNSSLTGESEPQSRCPDCTHENPLETRNIIFFSTNCVEGTARGVVIATGDHTVMGRIASLTSGLTMGKTPIATEIEHFIHIITAVAVFLGVTFFFLSLILGYTWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTTGKTFPKSSDTWFYLARIAGLCNRADFKPHQESLPITKRTTTGDASESALLKFIEQSYSPVSEMRQKNPKVAEIPFNSTNKYQMSIHLLEDNSEA-HVLLMKGAPERILDFCSSFLLNGQEYPMDEEMKTDFQNAYIELGGLGERVLGFCFLNLPSN-FSKGFQFNTEELNFPMENLCFAGLISMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEANETAEDIAARLNISISQVSNKSIKAIVVHGSELKDMDSGQLDNILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIVLSIPLPLGTITILCIDLGTDMVPAISLAYETPESDIMKRLPRNPKTDNLVNDRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPLDLLGIRLYWDDTNLNDLEDTYGQQWTYEQRKVVEFTCQTAFFISIVIVQWADLIICKTRRNSLFKQG-MKNKVLIFGLLEETILAACLSYIPGMDVALRMYPLKINWWFCALPYSVLIFIYDEVRKLIIRRRPGGWLEKETYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV27-1", "uniprot_id": "AT1A4_MOUSE", "id": "Q9WV27-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-4", "aln": "-MEPGKEKEVEAPGELNQKPRPSTRSST---------TNRQPKMKRRKKDLEELKKEVVMDDHKLTLDELSAKYSVDLTKGLSILEAQDILFQNGPNVLTPPPTTPEWVKFCRQLFGGFSLLLWTGACLCFLAYGIHVNYYKENANKDNLYLGIVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRDGEKMQINVRDVVLGDLVEVKGGDQIPADIRVISAQGCKVDNSSLTGESEPQSRCPDCTHENPLETRNIIFFSTNCVEGTARGIVIATGDYTVMGRIASLTSGLQMGKTPIATEIEHFIHLITAVAVFLGVSFFWLSIILGYTWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTTGKTFPKSSDTWFYLARIAGLCNRADFKPHQESVPIAKRATTGDASESALLKFIEQSYNPVSEMRQKNPKVAEIPFNSTNKYQMSIHLLEDNSEA-HVLLMKGAPERIFDFCSSFLLNGQEYPMDEEMKMDFQNAYIELGGLGERVLGFCFLNLPSN-FSKGFQFNTDELNFPMENLCFAGLISMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNDTAEDIAARLNIPISQVNNKSVKAIVVHGSELKDMESQQLDDILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIILSIPLPLGTITILCIDLGTDMVPAISLAYESPESDIMKRLPRNPKTDNLVNNRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPLDLLGIRLYWDDTQLNDLEDSYGQQWTYEQRKVVEFTCQTAFFISIVIVQWADLIICKTRRNSLFKQG-MKNKILIFGLLEETVLAAFLSYVPGMDVSLRMYPLKINWWFCALPYSVLIFVYDEIRKLIIRRRPGGWLEKETYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13733-1", "uniprot_id": "AT1A4_HUMAN", "id": "Q13733-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-4", "aln": "-MGLWGKKGTVAPHDQSPRRRP-KKGLI---------KKKMVKREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQI-YFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQT-GKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQT-HVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSS-FSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQG-MRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13607-1", "uniprot_id": "ATNA_DROME", "id": "P13607-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "-MALRSDYEHGRADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEE-PADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQS-GVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQG-MRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09626-1", "uniprot_id": "ATP4A_RAT", "id": "P09626-1", "name": "Potassium-transporting ATPase alpha chain 1", "aln": "MGK-ENYELYSVELGTGPGGDMAAKMSKKK---------AGGGGGKKKEKLENMKKEMEMNDHQLSVSELEQKYQTSATKGLKASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDL-TTDDNLYLALALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILSAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTAQGLVVSTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFVVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQS-GQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYTFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRMPVDQVNKKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPRRDRLVNEPLAAYSYFQIGAIQSFAGFADYFTAMAQEGWFPLLCVGLRPQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSAFQQGFFRNRILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGVRCCPGSWWDQELYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64436-1", "uniprot_id": "ATP4A_MOUSE", "id": "Q64436-1", "name": "Potassium-transporting ATPase alpha chain 1", "aln": "MGKAENYELYSVELGSGPGGDMTAKMSKKK---------AGGGGGKKKEKLENMKKEMEINDHQLSVSELEQKYQTSATKGLKASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDL-TTDDNLYLAVALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILSAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTAQGLVVSTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFVVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQS-GQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSINKFQLSIHTLEDPRDSRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRMPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFADYFTAMAQEGWFPLLCVGLRPQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSVFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGVRCCPGSWWDQELYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20648-1", "uniprot_id": "ATP4A_HUMAN", "id": "P20648-1", "name": "Potassium-transporting ATPase alpha chain 1", "aln": "MGKAENYELYSVELGPGPGGDMAAKMSKKKK--------AGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDL-TTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQS-GQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :::::*: : *::: :: :: . * . * : * .*** : ** *** :** ::: **: *:* .: :* :*: * . . :::**. * **::** *.*:** **::*: **..::** * *** .:* : ::* **:**:* **::***:*:: :.. :*************.* .: *::.****:*: *:** .:***. *:*: ** *::*:** *:**: .**** **.**:.::: :*: .. ** :. : * * :::*::.*:** *********** *:*****:* ***:************** ****************:*:*** : ***:*::: : : * : *.:: ***** *: *: :.: *: . *****:**** * . . *.: *: *:**** **:*:*:* : .:::*******::: *:::: :*:* ::.. *:.**:.************ : :. : *: : :** . : *.**:*******::***** ***:***:**************** .***** .:*.*::* * .:.:.:*. :* *: * :*:*. :: : * : *:***********:***.*** .*:********************:**** ***.:*:****:**************:**********:* *:**.**.*: *:* :* .:***:* :*** *:* **:.*:::**** .*:***: **. *.*** * :* :** :*: ..* **. *::*: * ..:* *: :*: *:***:** :* ::* *.** * : * **::* **** * *:** ::* : ..: : :. *.* * : : :: :*: ..*... *::*** *:: :* *..* ::: **", "identical_positions": 448, "similar_positions": 287, "identity": "42.87%" }, { "cls_id": "homologset.agr.FB:FBgn0002922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02346-1", "uniprot_id": "MYOD1_RAT", "id": "Q02346-1", "name": "Myoblast determination protein 1", "aln": "----------MELLSPPLRDTDLLGPDGSLCSFATRDDFYDDPCFDSPD------LRFFEDLDPRLVHVGALLKPEEHAHFPTTVHPGP-------------------------------------GAREDEHVRAP---SGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPG-AAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDAAYYSEAS-SEPRPGKSAAVSSLDCLSSIVERISTDSPAAPSLLLPDAPPESPPGPPEETSSSDAEQ-GTQTPSPDSTPQCPAGSKPNPIYQVL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10085-1", "uniprot_id": "MYOD1_MOUSE", "id": "P10085-1", "name": "Myoblast determination protein 1", "aln": "----------MELLSPPLRDIDLTGPDGSLCSFETADDFYDDPCFDSPD------LRFFEDLDPRLVHMGALLKPEEHAHFPTAVHPGP-------------------------------------GAREDEHVRAP---SGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPG-AAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDTAYYSEAA-RESRPGKSAAVSSLDCLSSIVERISTDSPAAPALLLADAPPESPPGPPEGASLSDTEQ-GTQTPSPDAAPQCPAGSNPNAIYQVL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15172-1", "uniprot_id": "MYOD1_HUMAN", "id": "P15172-1", "name": "Myoblast determination protein 1", "aln": "----------MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPD------LRFFEDLDPRLMHVGALLKPEEHSHFPAAVHPAP-------------------------------------GAREDEHVRAP---SGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAP-SEPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQSPDAAPQCPAGANPNPIYQVL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90477-1", "uniprot_id": "MYOD1_DANRE", "id": "Q90477-1", "name": "Myoblast determination protein 1 homolog", "aln": "----------MELSDIPFP-------------IPSADDFYDDPCFNTND------MHFFEDLDPRLVHV-SLLKPDEHHHI------------------------------------------------EDEHVRAP---SGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNDAFETLKRCTSTNPNQRLPKVEILRNAISYIESLQALLRSQ-------EDNYYP--------VLEHYSGDSDASSPRSNCSDGMMDFMGPTCQTRRRNSYDSSYFNDTPNADARNNKNSVVSSLDCLSSIVERISTETPACPVLSVPEGHEESPCSPHEGSVLSDTGT---TAPSPTSCPQQQAQET---IYQVL---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZVU3-1", "uniprot_id": "D3ZVU3_RAT", "id": "D3ZVU3-1", "name": "Myogenic factor", "aln": "----------MDMTD--------------SCQFSPSEYFYDGSCIPSPE------DEFGDQFEPRVAAFGAHKAKLQ-------------------------------------------------GSDDEEHVRAP---TGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQ-------VENYYS----------LPGQSCSQPTSPTSNCSDGMPECNSP-VWSRKNSSFDSIYCPDVS--NACASDKSSLSSLDCLSSIVDRITSAEPSE--LALQDTASLSP------------------AASTNSQPATPGSSSSRLIYHVL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24699-1", "uniprot_id": "MYF5_MOUSE", "id": "P24699-1", "name": "Myogenic factor 5", "aln": "----------MDMTD--------------GCQFSPSEYFYEGSCIPSPE------DEFGDQFEPRVAAFGAHKAELQ-------------------------------------------------GSDDEEHVRAP---TGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQ-------VENYYS----------LPGQSCSEPTSPTSNCSDGMPECNSP-VWSRKNSSFDSIYCPDVS--NACAADKSSVSSLDCLSSIVDRITSTEPSE--LALQDTASLSP------------------ATSANSQPATPGPSSSRLIYHVL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13349-1", "uniprot_id": "MYF5_HUMAN", "id": "P13349-1", "name": "Myogenic factor 5", "aln": "----------MDVMD--------------GCQFSPSEYFYDGSCIPSPE------GEFGDEFVPRVAAFGAHKAELQ-------------------------------------------------GSDEDEHVRAP---TGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQ-------VENYYS----------LPGQSCSEPTSPTSNCSDGMPECNSP-VWSRKSSTFDSIYCPDVS--NVYATDKNSLSSLDCLSNIVDRITSSEQPG--LPLQDLASLSP------------------VASTDSQPATPGASSSRLIYHVL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22816-1", "uniprot_id": "MYOD_DROME", "id": "P22816-1", "name": "Myogenic-determination protein", "aln": "MTKYNSGSSEMPAAQTIKQEYHNGYGQPTHPGYGFSAYSQQNPIAHPGQN----PHQTLQNFFSRFNAVGDASAGNGGAASISANGSGSSCNYSHANHHPAELDKPLGMNMTPSPIYTTDYDDENSSLSSEEHVLAPLVCSSAQSSRPCLTWACKACKKKSVTVDRRKAATMRERRRLRKVNEAFEILKRRTSSNPNQRLPKVEILRNAIEYIESLEDLLQES----------------------STTRDGDNLAPSLSGKSCQSDYLSSYAGAYLEDKLSFYNKHMEKYG-QFTDFDGNANGSSLDCLNLIVQSINKSTTSPIQNKATPSASDTQ-------------------SPPSSGATAPTSLHVNFKRKCST--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19335-1", "uniprot_id": "MYF6_RAT", "id": "P19335-1", "name": "Myogenic factor 6", "aln": "---------------------------MMMDLFETGSYFF----YLDGEN-VTLQPLEVAEGSPLYPGSDGTLSPCQDQMPQEAGS----------------------------------------DSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAINYIERLQDLLHRLDQQEKM-----------------QELGVDPYSYKPKQEILEGADFLRTCSPQ-WPSVSDHSRGLVITAKEGGASVDASASSSLQRLSSIVDSISSEERKLPSVEEVVEK------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15375-1", "uniprot_id": "MYF6_MOUSE", "id": "P15375-1", "name": "Myogenic factor 6", "aln": "---------------------------MMMDLFETGSYFF----YLDGEN-VTLQPLEVAEGSPLYPGSDGTLSPCQDQMPQEAGS----------------------------------------DSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKM-----------------QELGVDPYSYKPKQEILEGADFLRTCSPQ-WPSVSDHSRGLVITAKEGGANVDASASSSLQRLSSIVDSISSEERKLPSVEEVVEK------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23409-1", "uniprot_id": "MYF6_HUMAN", "id": "P23409-1", "name": "Myogenic factor 6", "aln": "---------------------------MMMDLFETGSYFF----YLDGEN-VTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGS----------------------------------------DSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKM-----------------QELGVDPFSYRPKQENLEGADFLRTCSSQ-WPSVSDHSRGLVITAKEGGASIDSSASSSLRCLSSIVDSISSEERKLPCVEEVVEK------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6VNZ9-1", "uniprot_id": "MYF6_DANRE", "id": "Q6VNZ9-1", "name": "Myogenic factor 6", "aln": "----------------------------MMDLFETNAYFFNDLRYLEGDH-GTLDMPGVS---PLYEGNDSPLSPGQDPVPSETGC----------------------------------------ESSGEEHVLAPPGLQ-AHCEGQCLMWACKICKRKSAPTDRRKAATLRERRRLKKINEAFDALKKKTVPNPNQRLPKVEILRSAINYIEKLQDLLHSLDEQE-------------------QSNDTDPYTYNLKENHVTPSEYHWKKTCQSWQENPDHSSSQMAGHREG-AVLESSESSSLRRLSSIVDSISTEEPKARCPSQISEK------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15173-1", "uniprot_id": "MYOG_HUMAN", "id": "P15173-1", "name": "Myogenin", "aln": "-----------------------------MELYETSPYFYQEPRFYDGENYLPVHLQGFE--PPGYERTELTLSP-------EAP------------------------------------------GPLEDKGLGTP----EHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEE------------------------RDLRYRGGGGPQPGVPSECSSHSASCSPEWGSALEFSANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12979-1", "uniprot_id": "MYOG_MOUSE", "id": "P12979-1", "name": "Myogenin", "aln": "-----------------------------MELYETSPYFYQEPHFYDGENYLPVHLQGFE--PPGYERTELSLSP-------EAR------------------------------------------GPLEEKGLGTP----EHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEE------------------------RDLRYRGGGGPQPMVPSECNSHSASCSPEWGNALEFGPNPGDHLLAADPTDAHNLHSLTSIVDSITVEDMSVAFPDETMPN------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20428-1", "uniprot_id": "MYOG_RAT", "id": "P20428-1", "name": "Myogenin", "aln": "-----------------------------MELYETSPYFYQEPHFYDGENYLPVHLQGFE--PPGYERTELSLSP-------EAR------------------------------------------GPLEEKGLGTP----EHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEE------------------------RDLRYRGGGGPSRWYP--VNATPTAPPAVRSGAMHWSLVPTQEIICSQLT-LQVPTTCTPLRPSWTASRWRICLSPSQMKPCPTEIVCQAGCAWEPLSWCQTPPLLQQGPFKWGCPGAQKTALGCHKPDYPPSIHIRLTPSPAREFN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: .. : ** **** **:*:. ***:***:**:*** *:*:**: **: * *************.** *** *: ** . : . ", "identical_positions": 48, "similar_positions": 23, "identity": "12.06%" }, { "cls_id": "homologset.agr.FB:FBgn0002924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QWT9-1", "uniprot_id": "KIFC1_MOUSE", "id": "Q9QWT9-1", "name": "Kinesin-like protein KIFC1", "aln": "----------------------------MDVQAQRPPLLEVKRNVELKAALVKSSSRVPLSASRLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHTAAQKGPKKTGPRGCSAIGTV-LRSQKPVPAAPAQKPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTQTLE----LENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEEC-------------LGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQ----------------------------KTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLHLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PUA5-1", "uniprot_id": "E9PUA5_MOUSE", "id": "E9PUA5-1", "name": "Kinesin-like protein", "aln": "----------------------------MDVQAQRK-GREGKRNVELKAALVKSSSRLPLSASSLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHNAAQKGPKKTGPGGCSAVGTV-LRSQKPAPAAPA-KPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTETLE----LENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEEC-------------LGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQ----------------------------KTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDRPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLAGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLPLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI63-1", "uniprot_id": "KIFC1_RAT", "id": "Q5XI63-1", "name": "Kinesin-like protein KIFC1", "aln": "----MRGRGSRDTGTQSAAFASRPVRTTVDMQAQRAPLMEVKRNLELSTTLVKSSSRLPLPGSRLKRGPDQMEDGLEPAKKRTRGMGTVTKVDTSRPRGPPLSAVS-----TAAQKGPRKTGPRGCSAVGPV-LRNQKPAPAAPAQKPGTSTAPAVAG-KKPGKRPAWDLKGQLCDLHEELKQYREKTQTLD----RENQGLREQLREVQEQATTLGTERNTLEEELASVRRRAEQSQQKLETLGARVLELEEC-------------LGTKERLVQELQTERLQLQEERSTLSTQLEEREREFQASEAALSSSRAEVLCLRQ----------------------------KTAAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTRLCLSRSDDRRSTLTRAPAAATRHDFSFDRVFPPGSKQEEVFEEISMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGDCEIR---RAGPGSEELTVTNARYVPVSCEKEVEALLHLAQQNRAVARTAQNERSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLTLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BW19-1", "uniprot_id": "KIFC1_HUMAN", "id": "Q9BW19-1", "name": "Kinesin-like protein KIFC1", "aln": "------------------------------MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATG-LKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLD----QENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEER-------------LSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQ----------------------------ETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIR---RAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUU7-1", "uniprot_id": "Q1LUU7_DANRE", "id": "Q1LUU7-1", "name": "Kinesin-like protein", "aln": "-------------------------------------------------MNKENTSRLPVMSGKRAHTNSTDGEQQQPAQKKMR----KVEVEPSQ-RFRPAASVAPPRRPVAVKAPVKPLRPTGAATVAAAPARGDQRRPVAAVAKATAAVS----------RRPGWDLKGKVSDMEAKVQNYQSKVKTVN----QENECLKDSIAKVQRRTADIEQENNGLRRRLG----DCEKELVKLATVKDDLEHTTKE-------------RDGLQKDLSKLTEEHKVLEGLRDHLESELRNIQTQLAIQTSALGRCQDSLKESQE----------------------------LARNLEETVARQREELHLGEMERRKLHNTIQELKGNIRVFCRVRPLLTGNQSDILHIQLPPHDN-------KALTLAKMEESHTGRT--TDTQKSYNFSFDRVFGPRSSQSEVFEEISLLVQSALDGYNVCCFAYGQTGSGKTFTMEGGEQ--EELWGVIPRAVQQIFKSAKALSEQGWQYSFTASFVEIYNETLRDLLYKG-KPNKRPEHEIR---KVS--NNEITVTNLTYQKVNNEDEVHNLIMLANQNRSTARTCMNDHSSRSHSVFQLDIEGENTARDSKCKSMLCLVDLAGSERVQKSQSQG----ERFKEMTAINSSLTNLGIVIAALANKDS---FVPYRNSKLTYLLQNCLGGNSKTLMFANISPEEESFSESLNSLRFASKVNDCVIGTASANKK--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20480-1", "uniprot_id": "NCD_DROME", "id": "P20480-1", "name": "Protein claret segregational", "aln": "----MESRLPKPSGLKKPQMPIKTVLPTDRIRAGLGGGAAGAGAFNVNANQTYCGNLLPPLSRDLNNLPQVLERRGGGARAASPEPMKLGHRAKLRRSRSACDINELRGNKRTAAAPSLPSIPSKVSRLGGALTVSSQRLVRPAAPSSITATAVKRPPVTRPAPRAAGGAAAKKPAGTGAAASSGAAAAAPKRIAPYDFKARFHDLLEKHKVLKTKYEKQTEDMGELESMPQQLEETQNKLIETESSLKNTQSD-------------NECLQRQVKQHTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTE---------------------ELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDES--------------TVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPES----VGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNE-----QKDMEIR---MAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESPKTS--------TRMTETKNINRSLSELTNVILALLQKQD---HIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSSTQSNNSGSFDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17119-1", "uniprot_id": "KAR3_YEAST", "id": "P17119-1", "name": "Kinesin-like protein KAR3", "aln": "MESLPRTPTKGRSTQHLSTPSPKNDILAMNGHKRRNTTTPPPKHTLLKPQRTDIHRHSLASQSRISMSPNRELLKNYKGTANLIYGNQKSNSGVTSFYKENVNELNRTQAILFEKKATLDLLKDELTETKEKINAVNLKFETLREEKIKIEQQLNLKNNELISIKEEFLSKKQFMNEGHEIHLKQLAASNKKELKQMENEYKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVEQKHMLEKEEWLTEYQSQWKKDIELNNKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKEKEEETTRLRDEVALKQKTNLETLEKIKELEEYIKDTELGMKELNEILIKEETVRRTLHNELQELRGNIRVYCRIRPALKNLENSDTSLINVNEFD------------DNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGD------GIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERINVSQVVG----DRLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLVSRK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : : . . : . . :. .: * : . : .. :* : : .: .: : : * : *: *** : :*:*****:**:** * . . : *.**::* . : ::*: :. *:**:**** :* ***********:** . *:** :: :*. . ** *.. . ::***** : *** . . :: .: ::* : . : :: *. *:.* *. *.:*****:: :.: * :: . . : ******** . . *: * ** **: * ** ** : :. .:*:******:** .* *.:* *** *:** .. ..*:::*****:.**. : . . ", "identical_positions": 116, "similar_positions": 124, "identity": "14.97%" }, { "cls_id": "homologset.agr.FB:FBgn0002931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA26-1", "uniprot_id": "D4AA26_RAT", "id": "D4AA26-1", "name": "Protein atonal homolog 8", "aln": "------MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPVRRANG--YKTFRLDLEAPEFGATASATAATN-------GLRDRT---QPFPIATPVPASVAPAVPPGGGTDTAREFRGIRAPEVSDARKRGFALGTVGPGLPTPPPPP---------------ASQSLAPGDPEVQPLREQALRPRILLCAPPARPTPSAPLAPPAVPQESPVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKR----PGEATAASTEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NA2-1", "uniprot_id": "ATOH8_MOUSE", "id": "Q99NA2-1", "name": "Transcription factor Atoh8", "aln": "------MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPVRRANG--YKTFRLDLEAPELGATVSTTAATN-------GLRDRT---QPFPIATPVPASVAPAVPPGGGTDTAREFRGIRAPEVSDARKRGFALGTVGPGLPTPPPPP---------------ASQSLAPGDPEAHSFREQALRPRILLCAPPARPTQSAPLAPPAAPQESPVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKR----PGEATAASTEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SQ7-1", "uniprot_id": "ATOH8_HUMAN", "id": "Q96SQ7-1", "name": "Transcription factor ATOH8", "aln": "------MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPARRANG--YKTFRLDLEAPEP-----RAVATN-------GLRDRTHRLQPVPVPVPVPVPVAPAVPPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPP-------------PAPQSQAPGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPP-ESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKR----PGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D2CLZ9-1", "uniprot_id": "ATOH8_DANRE", "id": "D2CLZ9-1", "name": "Transcription factor atoh8", "aln": "------MKN-PHLN-SPCK--ILNTVSGDKKMKRKAREPIKHVSEDHYPYFKLYKNPHLM-----AETLGD-------GSPQET---HRSEIITSRDDSVRNDVLN---TAVDMRINTITAAEVPDSKLR----------------------------------------------SVSEKTVNSKIVQASPQVS-VLSAPQVFPLERVVLSQRAASQAPAGGS--------------ERAESPRKR----AGEPSGVVTEIKAIQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLAQLADLDYTPDHRNMSFRECVEQCTRTLQAEGRSKKRKE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPI8-1", "uniprot_id": "Q9VPI8_DROME", "id": "Q9VPI8-1", "name": "", "aln": "MANTNTEKLYMQLSASELSAIIMKDSPNSNDRDAGFCSASSESEGGDDLVVEHARSGSPDIRPKGTDSADSKPIALVRNKRKSSEPFKVVGLTTPNSKSMPGPPSSASMNATGPLKKRIRYTSSADSAVVLTPPAIDSPPPNSCIPSTLRLQHEIMPNPAHIYVRHPGVTTLHRSLAAHPEQLEPLALVTTKKQCVDQAGPKIEAFSALLIGKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLAPISRPHQHQRNYKNMTRERRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSRMAGEDYSADQSVPSIATCLEAVTSTIQTEGKVKRKKDE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. . . :: . :. . .. . . .. . . . . : : : .. .: . . .. .*: . :.. : : :.* . :.:. . .* ... : * : : **: ***************:*:**: **.*: ******::**:**.***:*:::*. **:.*: *: *:: * *:*:**: *::*: ", "identical_positions": 56, "similar_positions": 80, "identity": "15.56%" }, { "cls_id": "homologset.agr.FB:FBgn0002932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZN22-1", "uniprot_id": "A0A8I5ZN22_RAT", "id": "A0A8I5ZN22-1", "name": "E3 ubiquitin-protein ligase NEURL1", "aln": "---------------------------------------------MGNNFSSVSSLQRGNPSRASRGHPQNLKDSIGSSFPVPSHRCHHKQKHCPPALSGGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFSGVRTA-DPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALR-RPSLRCEADEARLSVSLCDLNVPGADGEDGAPPA---------GCPIPQNSLNSQHSRALPAQLDGDLRFHALRA----------------------GAHVRILDEQTVARLEHGRDERALVFTSRPVRVAETIFIKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPL-HSGDILGLVVNADGELHLSHNGAPAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMAERGGPSLPCSPASTPTSPSALGSRLSDPLLSTCGSGPLGGSAGGTAPNSPVSLPESPVTP-GLGQW--------------------------------------------------------------------------------------------------------SDECTICYEHAVDTVIYTCGHMCLCYSCGLRLKKALH-ACCPICRRPIKDIIKTYRSS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923S6-1", "uniprot_id": "NEUL1_MOUSE", "id": "Q923S6-1", "name": "E3 ubiquitin-protein ligase NEURL1", "aln": "---------------------------------------------MGNNFSSVSSLQRGNPSRASRGHPQNLKDSIGGSFPVPSHRCHHKQKHCPPTLSGGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFSGVRTV-DPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALR-RPSLRCEADEARLSVSLCDLNVPGADGDDGAPPA---------GCPIPQNSLNSQHSRALPAQLDGDLRFHALRA----------------------GAHVRILDEQTVARLEHGRDERALVFTSRPVRVAETIFIKVTRSGGGRAGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPL-HSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMTERGGPSLPCSPASTPTSPSALGIRLSDPLLSTCGSGPLGGSAGGTAPNSPVSLPESPVTP-GLGQW--------------------------------------------------------------------------------------------------------SDECTICYEHAVDTVIYTCGHMCLCYSCGLRLKKALH-ACCPICRRPIKDIIKTYRSS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76050-1", "uniprot_id": "NEUL1_HUMAN", "id": "O76050-1", "name": "E3 ubiquitin-protein ligase NEURL1", "aln": "---------------------------------------------MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTA-DPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALR-RPSLRREADDARLSVSLCDLNVPGADGDEAAPAA---------GCPIPQNSLNSQHSRALPAQLDGDLRFHALRA----------------------GAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPL-HSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTP-GLGQW--------------------------------------------------------------------------------------------------------SDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALH-ACCPICRRPIKDIIKTYRSS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PHX8-1", "uniprot_id": "A0A8M9PHX8_DANRE", "id": "A0A8M9PHX8-1", "name": "E3 ubiquitin-protein ligase NEURL1", "aln": "---------------------------------------------MGN--SGIRSLHRGQQNRFQR-LPNSHKDSLGGPFPSTAHRCHHKPKRCLPLHQCGGVLMSPLLFHPNAKGSQIVMDLAQRSVKRQASFCNAITFSNRPIALYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDSLPKYACPDLVSQSGFWAKALPEEFANEGNLISFWVDKKGRVFYRINDSSPMLFFSGVRTT-EPLWALIDVYGLTRGVQLLESEVVPPDLLRPRSFTTVRGSTSLRREADTSRLSVSLCDLNLPQDDSRLRLPPAP-------VTCPIPQNSMNSQQSSLLPHTLECDIRFHQLRG-----------------------AHIKILNEQTVARSEHNREERTLVFTDRPLRIGETIFIKVIKSSPARFGSLSYGVTSCDPAVLRPSDLPYNPEALVDRKEFWAVCRVPTAL-QSADILGFLVTQEGEVILSHNGTNVGMQVCVDNSRPLWMFFGLHGAVTQLRILGSTFLGDARDPSSPGSPSASPSG--LCGGSPEPSLHERGCSAAFCSSTEGTTPNSPINLPKSPTFPSASGSW--------------------------------------------------------------------------------------------------------LDECSICYENTVDTVIYTCGHMCLCYTCGLRLKKMAN-ASCPICRRAIKDIIKTYRST--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NB17-1", "uniprot_id": "A0A8M1NB17_DANRE", "id": "A0A8M1NB17-1", "name": "", "aln": "---------------------------------------------MGG------QVTRSTSD------------------TVTLHCHPLKANMCPQLP-----APLPLCFHANTKGSQIVMDKTQRSVRRIASFCNAITFTSRPVGVYEQVRLKITKTQGCWSGALRVGFSIVDPSNISSAWLPRFACPDLVSEQGFWGRALPEEHCEEGTILSFWLDNIGRVFYRVNGGSPIFFFSGVPAG-EPVWGIIDIYGLTRGVHLLDCKMLPAEYLSP-AVTHEG--------MDDWNLSSGCSEFDLQEDLPSFSSSPN----------------ALN----LLLSHQLSDDLHFHSVHG-----------------------SALRLLTEHIAVRYYNRREACALVFTHRPLRCGECVFLKVSLRSS---GFLSYGFTSCNPAHVNSKHLPVDPDELLDRKEFWAFSSMTSAL-VGGDIIGFRATAEGEVLVSHNGGRARREMCVDNSAPLWMIFHLQTHIKQISILGTSRGYSPSCSETQRSIFSDASHLSANQIHSTTIRRCTDSSQPRPHSLSSSLGTAFGSLSSE--SPSCCALT--------------------------------------------------------------------------------------------------------GEECLICCDRPVDSVLYACGHMCVCSDCGVKLTETSN-PSCPVCRSPIRDIIKIYRSM--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8MQ27-1", "uniprot_id": "NEU1B_HUMAN", "id": "A8MQ27-1", "name": "E3 ubiquitin-protein ligase NEURL1B", "aln": "---------------------------------------------MGNTVHRTLPDPSPPAR------------------------LLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVG-GPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRG-----------------------PDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVP-SGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRL----LGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIK--------------------------------------------------------------------------------------------------------NGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQAR-ACCPICRRPIKDVIKIY-----RP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0MW30-1", "uniprot_id": "NEU1B_MOUSE", "id": "Q0MW30-1", "name": "E3 ubiquitin-protein ligase NEURL1B", "aln": "---------------------------------------------MGNTVHRTLPDSSPPAR------------------------LLATRPCYGPGPERRAVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVG-GPLWALIDVYGITDEVQLLESTFADTLTPLRLGQARLSACPPPGSHDAANFDNNELENNQVVAKLGHLALGRP---------DAAVPCVARERPRPASSPALLDAELRFHATRG-----------------------PDVSLSADRRLACAPRPDGGRTLVFSERPLRPGESLCVEVGRPGLAAPAAVAFGITSCDPGALRPSELPADPAALLDRKEYWVVARAGPVP-SGGDALSFTLRPGGDVLLAVNGRPRGRLLCVDTSQALWAFFAVRGGVAGQLRL----LGTLQSSSETMTPSGSFSGSQDDSDSDMTFGVNQSSSASESSLVTAPSSPLSPPVSPAFSAPEPTGSR--------------------------------------------------------------------------------------------------------NGECTVCFDSEVDTVIYTCGHMCLCHGCGLRLRRQAR-ACCPICRRPIKDVIKIY-----RP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M870-1", "uniprot_id": "NEUL3_RAT", "id": "Q5M870-1", "name": "E3 ubiquitin-protein ligase NEURL3", "aln": "---------------------------------------------MG-------SRLSPEAN------------------------AEVPR--------------EALSFHGDATGAQVHLDDQRSTARRRSTFHDGIVFSQRPVWPGERVALRVLRHEDGWCGGLRVGFTRLDPAQVAASCLPPFVCPDLEEQSPTWAALLPEGFVRAGNVVCFWVNRRGWLFAKVNAGRPLLLRKDVLVQGAPLWAVMDVYGTTKAIELLDPKAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AWITSGE-------------------------------------------------------------------------------------------------------------------------PMPESEVTS--------------------------------------------------------------------------------------------------------GEECVICFHNTANTRLMPCGHSQFCGSCAWHIFKDT--ARCPMCRWQIEEVAVEP---SVKSGEGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJC5-1", "uniprot_id": "NEUL3_MOUSE", "id": "Q8CJC5-1", "name": "E3 ubiquitin-protein ligase NEURL3", "aln": "---------------------------------------------MG-------SLLSPEAN------------------------AEVPR--------------EALSFHGNATGAQVHLDDQRSTARRRSTFHDGIVFSQRPVWPGERVALRVLRHEEGWCGGLRVGFTRLDPAQVAASCLPPFVCPDLEEQSPTWAALLPEGFVRAGNVVCFWVNRRGWLFAKVNAGRPLLLRKDVLVQGAPLWAVMDVYGTTKAIELLDPKAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AWIRSGE-------------------------------------------------------------------------------------------------------------------------PVPESEVIS--------------------------------------------------------------------------------------------------------GEECVICFHNTANTRLMPCGHSHFCGSCAWHIFKDT--ARCPICRWQIEEVAVVS---SLKAEEGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EH8-1", "uniprot_id": "NEUL3_HUMAN", "id": "Q96EH8-1", "name": "E3 ubiquitin-protein ligase NEURL3", "aln": "---------------------------------------------MG-------AQLCFEAN------------------------AKAPR--------------EALRFHAEAKGAQVRLDTRGCIAHRRTTFHDGIVFSQRPVRLGERVALRVLREESGWCGGLRVGFTRLDPACVSVPSLPPFLCPDLEEQSPTWAAVLPEGCALTGDLVRFWVDRRGCLFAKVNAGCRLLLREGVPVG-APLWAVMDVYGTTKAIELLDPTASRLPTPM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PWDLSNK-------------------------------------------------------------------------------------------------------------------------AVPEPKATP--------------------------------------------------------------------------------------------------------GEECAICFYHAANTRLVPCGHTYFCRYCAWRVFSDT--AKCPVCRWQIEAVAPAQGPPALRVEEGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29503-1", "uniprot_id": "NEUR_DROME", "id": "P29503-1", "name": "Protein neuralized", "aln": "MGLSDIPANYMQGSHPHLTLHPQQQHHQNQQHLQHLQQMQQLHNAMPTPAQQAAQVLAMESNELLMSTKDKLSSK--KKMHLLKKIKKRFGLVRRSPSSCPGPNNLPPLQFHSVHGDNIRISRDGTLARRFESFCRAITFSARPVRINERICVKFAEISNNWNGGIRFGFTSNDPVTLEG-TLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYYVNGAGDVIYGINNEEKGVILTGIDTR-SLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVPAQQQQMPQPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLERHVMPSLQSLHLAGNGGSVASVEQAAIAHDLANGLPPLRYNANGRLIPVPFHNTKGRNVRLSQDRFVASRTESDFCQGYVFTARPIRIGEKLIVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSDFLLDRPEYWVVSKDIAAAPQRGDEIAFFVAPNGEVSISKNNGPAVVVMHVDQSLQLWAFLDVYGSTQSLRMFRQQLPNMVAYPSQPQVNVNASSSSACNAASTSRMLPMTESMSSLNAGATAKLLHHPSQLSVAQSTSTLASAGGVNGSRMISMPSNGDILQIQPNGGGTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGACSSGTLISTTSSQYIEQPIANSTNNAANKWKDSLSDQQSTDSSAECTICYENPIDSVLYMCGHMCMCYDCAIEQWRGVGGGQCPLCRAVIRDVIRTYTT---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . * :: :. . * :* .:.*: **: *:: ::. * *.:*.**: ** : :* : **** . *. * * . :: :: : * :: :* .: .: . :* ::*:** :.:*: * . . ** :* :: : *** .* *. . **:** *. : ", "identical_positions": 44, "similar_positions": 62, "identity": "5.74%" }, { "cls_id": "homologset.agr.FB:FBgn0002936", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35176-1", "uniprot_id": "CYPD_YEAST", "id": "P35176-1", "name": "Peptidyl-prolyl cis-trans isomerase D", "aln": "MKLQFFSFITLFACLFTTAIFAKEDTAEDPEITHKVYFDINHGDKQIGRIVMGLYGLTTPQTVENFYQLTISRDPKMGYLNSIFHRVIPNFMIQGGDFTHRSGIGGKSIFGNTFKDEN--FDVKHDKPGRLSMANRGKNTNGSQFFITTVPCPWLDGKHVVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVESGELETVPLDNK-DAAKLQEEIKAEASEAAHDEL----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8I6AP42-1", "uniprot_id": "A0A8I6AP42_RAT", "id": "A0A8I6AP42-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "------------------------------MVNSTVFFNITANGELLACVSFKLFADKVPKTAENFHALSTG-EKGFGYKGSSFHRIIPGFMYQGGDFTRHNGTGGKSIYREKFEDEN--FILKHTGPSILSMANAGPNTNGSQFFICTAKTEWLG--------------------------------QACGLREGERRHGHCGSH-GAFWVQEWQDQ--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15425-1", "uniprot_id": "CYPR_DROME", "id": "P15425-1", "name": "Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme", "aln": "-------MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :::::. . : :. : : *:. .*:*. ** : .* .* ***:: *: ****:.. .* *. **: : * **: : ::* *. *.*** * :***.**:: *. **. . . ** . : . ", "identical_positions": 39, "similar_positions": 49, "identity": "15.98%" }, { "cls_id": "homologset.agr.FB:FBgn0002937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70276-1", "uniprot_id": "RPE65_RAT", "id": "O70276-1", "name": "Retinoid isomerohydrolase", "aln": "------------------------------------------MSIQIEHPAGGYKKLFETVEELSTPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYYRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFRGV----EITDNALVNIYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGATAHPHIESDGTVYNIGNCFGKNFTVAYNIIKIPP----LKADKEDPINKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNESMGVWLHVADKKRRKYFNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRNAMKAPQPEVRRYVLPL------------------------------------------------------------TIDKAD-TGRNLVTLPHTTATAILCSDET--IWLEPEVLFSGP---RQAFEFPQINYQKCGGKPYTYAYGLGLNH--FVPDKLCKLNVKTKEIWMWQEPDSYPSEPIFVSQPDALEEDDGVVLSVVVSPGAGQKPAYLLVLNAKDLSEIARAEVETN--IPVTFHGLFKKP----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZQ5-1", "uniprot_id": "RPE65_MOUSE", "id": "Q91ZQ5-1", "name": "Retinoid isomerohydrolase", "aln": "------------------------------------------MSIQIEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFKGV----EVTDNALVNIYPVGEDYYACTETNFITKINPETLETIKQVDLCNYISVNGATAHPHIESDGTVYNIGNCFGKNFTVAYNIIKIPP----LKADKEDPINKSEVVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNESMGVWLHVADKKRRKYFNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRNAMKAPQPEVRRYVLPL------------------------------------------------------------TIDKVD-TGRNLVTLPHTTATATLRSDET--IWLEPEVLFSGP---RQAFEFPQINYQKFGGKPYTYAYGLGLNH--FVPDKLCKMNVKTKEIWMWQEPDSYPSEPIFVSQPDALEEDDGVVLSVVVSPGAGQKPAYLLVLNAKDLSEIARAEVETN--IPVTFHGLFKRS----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16518-1", "uniprot_id": "RPE65_HUMAN", "id": "Q16518-1", "name": "Retinoid isomerohydrolase", "aln": "------------------------------------------MSIQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFFSYFRGV----EVTDNALVNVYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFGKNFSIAYNIVKIPP----LQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYLNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPL------------------------------------------------------------NIDKAD-TGKNLVTLPNTTATAILCSDET--IWLEPEVLFSGP---RQAFEFPQINYQKYCGKPYTYAYGLGLNH--FVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEIN--IPVTFHGLFKKS----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9C3R9-1", "uniprot_id": "RP65B_DANRE", "id": "A9C3R9-1", "name": "All-trans-retinyl ester 13-cis isomerohydrolase", "aln": "------------------------------------------MVSRLEHPAGGYKKVFESCEELAEPIPAHVSGKIPAWLSGSLLRMGPGLFEIGDEPFNHLFDGQALIHKFDLKDGRVTYHRKFIRTDAYVRAMTEKRVVITELGTAAYPDPCKNIFSRFFTYFQGT----EVTDNCSVNIYPIGEDFYACTETNFITKVNPDTLETIKKVDLCNYLSVNGLTAHPHIEADGTVYNIGNCFGKNMSLAYNIVKIPP----LQEEKSDPLAMSKVLVQFPSSERFKPSYVHSFGMTENHFVFVETPVKINLLKFLTSWSIRGSNYMDCFESNDRMGTWFHLAAKNPGKYIDHKFRTSAFNIFHHINCFEDQGFIVVDLCTWKGHEFVYNYLYLANLRQNWEEVKKAALRAPQPEVRRYVLPL------------------------------------------------------------DIHREE-QGKNLVSLPYTTATAVMCSDGT--VWLEPEVLFSGP---RQAFEFPQINYSKFNGKDYTFAYGLGLNH--FVPDRICKLNVKSKETWIWQEPDAYPSEPLFVQSPDAEDEDDGVLLSIVVKPGVSQRPAFLLILKATDLTEIARAEVDVL--IPLTLHGIYKP-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A9C3R8-1", "uniprot_id": "RP65C_DANRE", "id": "A9C3R8-1", "name": "Retinal Mueller cells isomerohydrolase", "aln": "------------------------------------------MVSRLEHPAGGYKKVFESCEELAEPIPAHVSGEIPAWLSGSLLRMGPGLFEVGDEPFYHLFDGQALLHKFDLKDGRVTYHRRFIRTDAYVRAMTEKRVVITEFGTTAYPDPCKNIFSRFFTYFQGI----EVTDNCLVNIYPIGEDFYACTETNFITKVDPDTLETVKKVDLCNYLSVNGLTAHPHIEADGTVYNIGNCFGKNMSLAYNIVKIPP----LQEDKSDQFEKSKILVQFPSSERFKPSYVHSFGITENHFVFVETPVKINLLKFLTSWSIRGSNYMDCFESNDKMGTWFHLAAKNPGKYIDHKFRTSAFNIFHHINCFEDQGFIVVDLCTWKGHEFVYNYLYLANLRQNWEEVKKAALRAPQPEVRRYVLPL------------------------------------------------------------DIHREE-QGKNLVSLPYTTATAVMRSDGT--VWLEPEVLFSGP---RQAFEFPQINYSKFNGKDYTFAYGLGLNH--FVPDRICKLNVKSKETWIWQEPDAYPSEPLFVQSPDAEDEDDGVLLSIVVKPGVSQRPAFLLILKATDLTEIARAEVDVL--IPVTLHGIYKP-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PBW5-1", "uniprot_id": "RP65A_DANRE", "id": "Q6PBW5-1", "name": "Retinoid isomerohydrolase", "aln": "------------------------------------------MVSRFEHPAGGYKKIFETAEELNEPLPATVTGRIPSFIKGSLLRLGPGLFEAGAEPFYHLFDGQALMHKFDFSNGQVTYFRKFVKTDAYVRAITEKRVVITEFGTCAYPDPCKNIFSRFFSYFKGV----EVTDNCLVNVYPIGEDFYAVTETNYITKVNVDTLETLKKVDMCNYVNINGVTAHPHIERDGTVYNIGNCMGKGASLAYNIVRIPP----TQKDKSDPIEKSKVVVQFPSAERFKPSYVHSFGMTENYFVFVETPVKINLLKFLSAWSIRGSNYMDCFESDEEKGTWIHIARKHPGEYIDYKFRTSAMGLFHHINCYEDSGFIVFDLCAWKGFEFVYNYLWLANLRANWEEVKRNAMIAPQPEVRRYVIPL------------------------------------------------------------DPFREE-QGKNLISLPYTTATATMRADGT--IWLEPEVLFSGP---RQAFEFPQINYRMVNGKNYTYAYGLGLNH--FVPDRICKLNVRTKETWVWQEPDSYPSEPLFVQTPDGVDEDDGILMTIVVSPG-AQRPTYCLILNAKDLSEIARAEVEIL--TPVTFHGMYKP-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9BYV7-1", "uniprot_id": "BCDO2_HUMAN", "id": "Q9BYV7-1", "name": "Carotenoid-cleaving dioxygenase, mitochondrial", "aln": "MFFRVFLHFIRSHSATAVDFLPVMVHRLPVFKRYMGNTPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKDKYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNVFERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKFIAVNGATAHPHYDLDGTAYNMGNSFGPYG-FSYKVIRVPP----EKVDLGETIHGVQVICSIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSK-IRGKAFSDGISWEPQCNTRFHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQD-NGRTLEVYQLQNLRKAGEGLDQVHNSAAKSFPRRFVLPL------------------------------------------------------------NVSLNAPEGDNLSPLSYTSASAVKQADGT--IWCSHENLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFRH--LVGDSLIKVDVVNKTLKVWREDGFYPSEPVFVPAPGTNEEDGGVILSVVITPN-QNESNFILVLDAKNFEELGRAEVPVQ--MPYGFHGTFIPI----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99NF1-1", "uniprot_id": "BCDO2_MOUSE", "id": "Q99NF1-1", "name": "Carotenoid-cleaving dioxygenase, mitochondrial", "aln": "-------------------------------------------MLGPKQSLPCIAPLLTTAEETLSAVSARVRGHIPEWLNGYLLRVGPGKFEFGKDRYNHWFDGMALLHQFRMERGTVTYKSKFLQSDTYKANSAGGRIVISEFGTLALPDPCKSIFERFMSRFEPP----TMTDNTNVNFVQYKGDYYMSTETNFMNKVDIEMLERTEKVDWSKFIAVNGATAHPHYDPDGTAYNMGNSYGPRG-SCYNIIRVPP----KKKEPGETIHGAQVLCSIASTEKMKPSYYHSFGMTKNYIIFVEQPVKMKLWKIITSK-IRGKPFADGISWEPQYNTRFHVVDKHTGQLLPGMYYSMPFLTYHQINAFEDQGCIVIDLCCQD-DGRSLDLYQLQNLRKAGEGLDQVYELKAKSFPRRFVLPL------------------------------------------------------------DVSVDAAEGKNLSPLSYSSASAVKQGDGE--IWCSPENLHHEDLEEEGGIEFPQINYGRFNGKKYSFFYGCGFRH--LVGDSLIKVDVTNKTLRVWREEGFYPSEPVFVPVPGADEEDSGVILSVVITPN-QSESNFLLVLDAKSFTELGRAEVPVQ--MPYGFHGTFVPI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XT5-1", "uniprot_id": "BCDO1_RAT", "id": "Q91XT5-1", "name": "Beta,beta-carotene 15,15'-dioxygenase", "aln": "----------------------------------------------------MEIIFGRNKKEQLEPLRATVTGSIPAWLQGTLLRNGPGMHTVGDSKYNHWFDGLALLHSFSIRDGEVFYRSKYLQSDTYNANIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHT--IPDFTDNCLINIMKCGEDFYATTETNYIRKIDPQTLETLEKVDYRKYVAVNLATSHPHYDEAGNVLNMGTSIADKGGTKYVMFKIPATAPGSKKKGKNPLKHSEVFCSIPSRSLLSPSYYHSFGVTENYVVFLEQPFKLDILKMATAY-MRGVSWASCMTFCKEDKTYIHIIDQKTRKPVPTKFYTDPMVVFHHVNAYEEDGCVLFDVIAYE-DNSLYQLFYLANLNKDFE---EKSRLTSVPTLRRFAVPL------------------------------------------------------------HVDKDAEVGSNLVKVSSTTATALKEKDDH--VYCQPEVLY-------EGLELPRINY-AHNGKPYRYIFAAEVQWS-PVPTKILKYDVLTKSSLKWSEESCWPAEPLFVPTPGAKDEDDGVILSAIISTD-PQKLPFLLILDAKSFTELARASVDVD--MHLDLHGLFIPDAGWNAVKQTPAKTQEDENSDHPTGLTAPGLGHGENDFTAGHGGKSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJS6-1", "uniprot_id": "BCDO1_MOUSE", "id": "Q9JJS6-1", "name": "Beta,beta-carotene 15,15'-dioxygenase", "aln": "----------------------------------------------------MEIIFGQNKKEQLEPVQAKVTGSIPAWLQGTLLRNGPGMHTVGESKYNHWFDGLALLHSFSIRDGEVFYRSKYLQSDTYIANIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHT--IPDFTDNCLINIMKCGEDFYATTETNYIRKIDPQTLETLEKVDYRKYVAVNLATSHPHYDEAGNVLNMGTSVVDKGRTKYVIFKIPATVPDSKKKGKSPVKHAEVFCSISSRSLLSPSYYHSFGVTENYVVFLEQPFKLDILKMATAY-MRGVSWASCMSFDREDKTYIHIIDQRTRKPVPTKFYTDPMVVFHHVNAYEEDGCVLFDVIAYE-DSSLYQLFYLANLNKDFE---EKSRLTSVPTLRRFAVPL------------------------------------------------------------HVDKDAEVGSNLVKVSSTTATALKEKDGH--VYCQPEVLY-------EGLELPRINY-AYNGKPYRYIFAAEVQWS-PVPTKILKYDILTKSSLKWSEESCWPAEPLFVPTPGAKDEDDGVILSAIVSTD-PQKLPFLLILDAKSFTELARASVDAD--MHLDLHGLFIPDADWNAVKQTPAETQEVENSDHPTDPTAPELSHSENDFTAGHGGSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAY6-1", "uniprot_id": "BCDO1_HUMAN", "id": "Q9HAY6-1", "name": "Beta,beta-carotene 15,15'-dioxygenase", "aln": "----------------------------------------------------MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSFTIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHT--IPDFTDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGNVLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFGVTENYVIFLEQPFRLDILKMATAY-IRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYE-DNSLYQLFYLANLNQDFK---ENSRLTSVPTLRRFAVPL------------------------------------------------------------HVDKNAEVGTNLIKVASTTATALKEEDGQ--VYCQPEFLY-------EGLELPRVNY-AHNGKQYRYVFATGVQWS-PIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVSTD-PQKLPFLLILDAKSFTELARASVDVD--MHMDLHGLFITDMDWDTKKQAASEEQRDRASDCHGAPLT-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFG6-1", "uniprot_id": "A0A8M1PFG6_DANRE", "id": "A0A8M1PFG6-1", "name": "", "aln": "----------------------------------------------------MLSFFWRNGIETPEPLKADVSGSIPPWLQGTLLRNGPGLFSVGNTSYKHWFDGMALIHSFTFKDGEVFYRSKYLKSETYKKNIAADRIVVSEFGTMVYPDPCKNIFSRAFSYMMNA--IPDFTDNNLINIIKYGEDYYASSEVNYINQIDPLTLETLGRTNYRNHIAINLATAHPHYDEEGNTYNMGTAIMNLGRPKYVIFKVPANTSD-KENKKPALSEVEQVCSIPIRSSLYPSYFHSFGMTENYIIFVEQAFKLDIVKLATAY-FRDINWGSCLKFDQDDINVFHLVNKKTGKAVSVKYYTDPFVTFHHINAYEDDGHVVFDLITYK-DSKLYDMFYIQNMKQDVKRFIETNKDFAQPVCQRFVLPV------------------------------------------------------------NVDKETPQDINLVKLQDTTATAVLKEDGS--VYCTPDIIF-------KGLELPAINY-KFNSKKNRYFYGTRVEWS-PYPNKVAKVDVVTRTHKIWTEEECYPSEPVFIASPDAVDEDDGVILSSVVSFN-PQRPPFLVVLDAKSFKEIARATIDAS--IHMDLHGLFIHDKST-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFS2-1", "uniprot_id": "NINAB_DROME", "id": "Q9VFS2-1", "name": "Carotenoid isomerooxygenase", "aln": "-----------MAAGVFKSFMRDFFAVKYDEQRNDPQAERLDGNGRLYPNCSSDVWLRSCEREIVDPIEGHHSGHIPKWICGSLLRNGPGSWKVGDMTFGHLFDCSALLHRFAIRNGRVTYQNRFVDTETLRKNRSAQRIVVTEFGTAAVPDPCHSIFDRFAAIFRPD----SGTDNSMISIYPFGDQYYTFTETPFMHRINPCTLATEARICTTDFVGVVNHTSHPHVLPSGTVYNLGTTMTRSG-PAYTILSFPHG--------EQMFEDAHVVATLPCRWKLHPGYMHTFGLTDHYFVIVEQPLSVSLTEYIKAQ-LGGQNLSACLKWFEDRPTLFHLIDRVSGKLVQT-YESEAFFYLHIINCFERDGHVVVDICSYR-NPEMINCMYLEAIANMQTNPNYATLFRGRP--LRFVLPLGTIPPASIAKRGLVKSFSLAGLSAPQVSRTMKHSVSQYADITYMPTNGKQATAGEESPKRDAKRGRYEEENLVNLVTMEGSQAEAFQGTNGIQLRPEMLCDWG------CETPRIYYERYMGKNYRYFYAISSDVDAVNPGTLIKVDVWNKSCLTWCEENVYPSEPIFVPSPDPKSEDDGVILASMVLGGLNDRYVGLIVLCAKTMTELGRCDFHTNGPVPKCLHGWFAPNAI--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : . * :* :: * *** *** * : * ** **:* * : * * * ::: ::: *:*::*:** . ****:.:*.: : : *** :. ::* :*. :: ::: * : ..: : *:*** *.. *:*. * :. .* . . :. *.* *:**:* ::.:::* .. :.: : .: : : :*: : : . : : .: * :* :* .* ::.*: : : : . *:.:*: ** : .: : : : : * * : * .* : :. : * :: .: * * :*:**:*: *. .**.*:::: :: . .. ::* *. : *:.*. . :** : ", "identical_positions": 84, "similar_positions": 141, "identity": "12.02%" }, { "cls_id": "homologset.agr.FB:FBgn0002938", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LWJ6-1", "uniprot_id": "F1LWJ6_RAT", "id": "F1LWJ6-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------MAAASEVSGEHAEDKTGKHLYGLFHYNSMMLRLESLPDPMDTWEIRETIGKGTYGKVYKVANRRDGSLAAVKILDSVN-------DVDEEVEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCGKRLDEALISYILYGSLLGLQHLHHHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDNWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFIKGTQGKVLFLQKQLAKVLWDQKHQNPVAK------------TRHERMHTGR-PHHVEDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKTENAHLIVQHLTFLGKANNQTLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYIYAGLYHQKKLAEFRLPEEKPPRYIAAETERVTQDITSK----ESYRRQFDVIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNPEALENAASVLCINSEELQEALTSHCVVTRGETIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQVQFYFNQHVFALEQMEYKKEGVDAVLVQYEDNRPLLDMFLQKPLGLLALLDEESRFPQGTDQTLVDKFEDNLRCKFFWRPKGVELSFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITASSRSLP--------------------PHFSAGR------------------AKVDTLEVIRHPEETTNMKRQTMASYFRYSLMDLLSKMVVGQ---PHFVRCIKPNDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSHRILFEEFVRRYYYLAFRAHQTPPANKESCVAILEKSRLDHWVLGKTKVFLKYYHIEQLNLLLREVMGRVVMLQAYTKGWLGARRYK---------RAKEKREKSAITIQSAWRGYDTRR-----------------------------KFKQTRHRRNESAAHTQAVLQTTPDE------------------------------------------------------------KRFPDSGVESNSRHEETSR----------------------------------------------------------------------------------------------------------------------NCPAEADTDWHPQTQSSPASS--------------------------------------------------------------------------------------------------------------------DVTSGHADKEAGNAVAE---------LSVAGTDGSPSRVCHTATAHHRLSPCEVSLKPGSEEGLSQKQRAP------------------------------------RRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSQRKPRKLGQIKVLDGEDQYYKCLSPG-------------------------------------------------ACAPEETHSAHSFFFSLPPGEDSFAQH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1EG27-1", "uniprot_id": "MYO3B_MOUSE", "id": "Q1EG27-1", "name": "Myosin-IIIb", "aln": "-----------------------------------------------MMLGLESLPDPMETWEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVS-------DMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCGKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFIKGTQGKVLCLQKQLAKVLQDQKHRNPVAK------------TRHERMHTGR-PHRVEDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKTESAHLIVQHLTFLGKADNQTLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYIYAGLYHQKKLAEFRLPEEKPPRYIAGETERVMQDITSK----ESYRTQFEAIQHCFKIIGFADKEVHSVYRILAGILNIGSIEFAAISSQHQTDKSEVPNPEALENAACVLCISSEELQEALTSHCVVTRGETIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYKNEGVDAVLVQYEDNRPLLDMFLQKPLGLLALLDEESRFPQGTDQTLVDKFEDNLRCKFFWRPKGVELCFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRAKITASSRSLP--------------------PHFSAGR------------------AKVDTLEVIRHPEETTNMKRQTMASYFRYSLMDLLSKMVVGQ---PHFIRCIKPNDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSHRIFFEEFVKRYYYLAFRAHQTPPANKESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVMGRVVMLQAYTKGWLGARRYK---------RAKEKREKGAITIQSAWRGYDARR-----------------------------KLKQRSRRRSESEAHIHTVLQTTPDQ------------------------------------------------------------KYCPDSGGESNRGHEETSR----------------------------------------------------------------------------------------------------------------------NCPAEADTDGHPQAQSPPTGC--------------------------------------------------------------------------------------------------------------------DVTSGHADTAAGYTVAE---------LSVAGTDVSPSLVYHTASAHQRLSPCEDSLKPGSEEGLSQKQRAP------------------------------------RRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSQRKPRKLGQIKVLDGEDQYYKCLSPG-------------------------------------------------ACAPEETHSVHPFFFSSSPREDPFAQH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXR4-1", "uniprot_id": "MYO3B_HUMAN", "id": "Q8WXR4-1", "name": "Myosin-IIIb", "aln": "-----------------------------------MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVS-------DMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQNPVAK------------TRHERMHTRR-PYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSK----ESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITVASSSLP--------------------PHFSAGK------------------AKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQ---PHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYK---------RVREKREKGAIAIQSAWRGYDARR-----------------------------KFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRG----------------------------SVHRRSHSQAESNNGRTQTSS----------------------------------------------------------------------------------------------------------------------NSPAVTEKNGHSQAQSSPKGC--------------------------------------------------------------------------------------------------------------------DIFAGHANKHS-----------------VSGTDLLSSRICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTP------------------------------------RRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPV-------------------------------------------------DCIPEENNSAHPSFFSSSSKGDSFAQH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GFL4-1", "uniprot_id": "A0AC58GFL4_DANRE", "id": "A0AC58GFL4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAGHVNQGTDVVQSRGLENSEETERTEFYHLHGRIWRSFYGLYPYKSSMIGLESLADPSSDWDIVETIGKGTYGKVYKVINKKDGSQAAVKVLDPINNPSHTNRDVDEEIEAEYNILRSLSNHPNVVKFFGMFYKADELSGGQLWLVLELCNGGSVTDLIKGLLMRGKRLEEPIISYILCGALLGLQHLHNNRIIHRDVKGNNILLTTDGGVKLVDFGVSAQLTSARLRRNTSVGTPFWMAPEVIACEQQYDYSYDARCDVWSLGITAIELADGDPPLAEMHPVKALFKIPRNPSPTLRHPEQWCRSFSHFIAQCLIKDFETRPSVTHLLEHPFIKQAHGKDTLLRQQLSVLIREQQDVGSRTK------------TRHERINTRK-TLIIES----CPDDDLVNLELLDEETIIAHLQKRYQDLQIYTYVGDILIALNPFQNLSIYSPQFSKLYHGMKRSTNPPHIFATADAAYQSMVTLCKDQCIIISGESGAGKTESAHLIVQHLTFLGKANNRTLREKILQVNPLVEAFGNACTAINDNSSRFGKYLEMKFTPTGAVMGAKISEYLLEKSRVIKQATGEKNFHIFYYIYAGLYHQDNLRKYKLPNKTAPRYIDCVNGKVMQDIISS----KLYKEQFDAIQDCFRIIGFTEEEVNSVYRILAAILNTGNIEFASASSQHQSDKSEVPNSEALDNAAALLSIGSEELQEALTSHCVVTRGETIIRTNTVDKATVVRDAMSKALYGRLFSWIVNRINALLQPDTNICAAESGMNVGILDIFGFENFKKNSFEQLCINIANEQIQFYFNQHIFALEQIEYQSEGVDVSLVEYEDNRPILDMFLQKPMGLLSLLDEESRFPQATDQTLVDKFQDNLRNKYFWIPKRVELCFGIQHYAGQVLYNVSGFLEKNRDTLPADIVVVLRTSENRLLQQLFSSPLTKTGNLATSRARVTAASRSLP--------------------PQLNSGRNKSP-----------KYLLKVDTMEMMRHPEETTNMRRQTVASYFRYSLMDLLSKMVVGT---PHFVRCIKPNDDRQALRFNKERVMVQLRYTGILETVNIRRQGYSHRILIQEFVNRYYYLAFRAHQMPEGSKENAIIILQKAKLDYWVVGNTKVFLKYYHVEQLNLMLREVIARVVLMQAYTKGWLGARRYR---------REREKRRNGAVVIQSAWRGHVARQ-----------------------------NLKLIKREREQAAVQIQSVYRGYRVR------------------------------------------------------------KDYKQSRQWTGQPSSKRSS----------------------------------------------------------------------------------------------------------------------TNHSPDEKVVSVSADSGIGSS--------------------------------------------------------------------------------------------------------------------DASVPKTDKQS------------------------------DSRERAPLSKQGPTLK-------LHQHRSP------------------------------------RRRGQQPKLLNSPEDSLYYNHLNRSLDYQGSKRKPRKLGQIKLLDGEDEYYQLLSTI-------------------------------------------------EAVPEEDVLTGTSPNPTSTPPTISSR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZZK7-1", "uniprot_id": "D3ZZK7_RAT", "id": "D3ZZK7-1", "name": "Myosin-IIIa", "aln": "---------------------------------VQMTETFAMLPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIH-------DIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLKRGERMSEPIIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFITQIEGRDAILQKQLMEFIDIHQCLGSTEK------------ARHERIHTKKGNLNRSLISSLKDVDDLATLDVLDENTVSEHLEKCYSRDQIYIYVGDILIALNPFQSLGLYSTKLSKLYIGAKRTANPPHIFAVADLGYQSMVTYNADQCIVISGESGAGKTESAHLLVQHLTVLGKANNRTLQEKILQMNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLALYKLPENKPPRYLQNDNLRTVQDMMNN----SFYKSQYELIEQCFKVIGFTMEQLGSVYSVLAAILNVGNIEFSSVATEYQMDKSYICNHTALENSASLLCIQADELQEALTSHCVVTRGETIIRPNTVEKATDVRDATAKTLYGRLFSWIVNCINSLLKHDTSPSGN-EELNIGILDIFGFENFKKNSFEQLCINIANEQIQYYFNQHVFAWEQNEYLNEDVDARVIEYEDNRPLLDMFLQKPMGLLFLLDEESRFPKATDQTLVEKFEDNLKSQYFWRPKRMELSFGIHHYAGKVLYSASGFLAKNRDTLPTDIVLLLRSSENSVIRQLVNHPLTKTGNLPLSKTKNIVNYQMQN--------------------SEKSTN------------------LNKSETRDVTRHAYETTNVKTQTVSSYFRYSLMDLLSKMVVGQ---PHFVRCIKPNNDRQARKYDKEKVLIQLRCTGILETARIRRLGYSHRILFANFIKRYYVLCYKSSEEPPVSPDTCATILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLVLIQASVRAFLGAKRYQ---------ELQQKRKTSAVIIQSAARRHLLRK-----------------------------QGKKTSNVQSTAGMSVRAKDQEFDYKKNFETKRESFVKKHTENAVPTNESNIPTPN---NKESPSAGKTAPFRAEAKATN-VESNNRKYQTQKKMSNVYAEGQNQ---ELYIVGDSWVEVSP-------RQKYVQDLEESRK----------LRKEEKGDAVIQSYCQWYTEGSNFEESKATCLEGKATWEKPSCPGLWLTE-EIYLRKTLDPSLSQKSVYQNANSNEKEKKTSVVTQSAPLGN------LGKDYHLHGFLGEKDTGP------------------VDQAQE---------EDKAAVFIQSKYRNSKQKQQLGKDN------------LSPPFKNEKILSSPTEVARNTRNVYSCPTKQEGIHHLKM-----VDERESKLTSKKEACDLAMFSRQISKLSEEYFILQKNLNEIILAQQLKPLYLGICRH-KPINRHISTHQYLSGVSKGEESKILRPPRRPRKPKTLNNPEDSTYYYLLHKSTQEE--KRRPRKDSQGKLLGLEDFYYKELFPT---------HFGPKAHSSNAR---EWKAQEEPQDQRIESNERCWTASESEIPEEERISANPYDYRRLLRKTSQRQRLLQQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3H5-1", "uniprot_id": "MYO3A_MOUSE", "id": "Q8K3H5-1", "name": "Myosin-IIIa", "aln": "-----------------------------------------MLPLIGKTIIFDNFPDPSDTWEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIH-------DIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLKRGERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFITQIEGKDVILQKQLMEFIDIHQCLGSTEK------------ARHERIHTKKGNLNRSLISSLKDVDDLATLDVLDEPTASPHLHPCHSRDQIHIHVADILIALNPFQSLGIYSPKLSRLYIGAKRTANPPHIFAMADLGYQSMVTYNADQCIVISGESGAGKTESAHLLVQQLTVLGKANNRTLQEKILQMNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAMGEKNFHIFYYIYGGLAEKKKLALYKSPEHKPPRYLQNDNLRTVQDMMNN----SFYKSQYELIEQCFKVIGFTMEQLASVYSVLAAILNVGNIEFSSVATEYQMDKSYICNHTALENCASLLCIQADELQEALTSHCVVTRGETIIRPNTVEKAADVRDAMAKTLYGRLFSCIVNCINSLLKHDTSPSGD-EELNIGILDIFGFENFKRNSFEQLCINIANEQIQYYFNQHVFAWEQNEYLNEDVDARVIEYEDNRPLLDMFLQKPMGLLSLLDEESRFPKATDQTLIEKFEDNLKSQYFWRPKRMELSFGIHHYAGKVLYSASGFLAKNRDTFPTDIVLPLRSSENSVIRQLVNHPLTKTGNLPLSKTKNIVNYQMWN--------------------SEKSTN------------------LTKGETRDVTCHACETTNVKTQTVSSYFRYSLMDLLSKMVVGQ---PHFVRCIKPNNERQARKYDKEKVLLQLRCTGILETARIRRLGYSHRILFANFIKRYYILCYKSSEEPPVSPDTCAAILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEATNKLVLIQASVRAFLGARRYQ---------ELQQKRKSSAVIIQSAARGHLVRK-----------------------------QRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQTENAVPTNESNTSTPN---NKESPSAGKTAPFIAESKATN-VESNNRRYHTQKKMSNVYAEGQNQ---ELYIVEDTWAEVSP-------RQKYVQDLEESRK----------MRKEEKGDAVIQSYCQWYTEGSNFEESKATCLEGRETWERTSCPGLWLTE-EIYLRKTLDPTLSQKSVYQNADGKEKEHKVSVVTQNAPLGN------LERDYHLLGFLGEEDTGP------------------VPQAQE---------EHK-AVSIHSKYQSSKKKQQLGKDR------------LAPPFKNQKILSSSTEVAKTTHNVYPCPTKQEGVHHSKM-----VDERDSKMASKKEAWDLAMFSRQISKLSEEYFILQKNLNEIILAQQLKPFYLGIYRH-KPINRHVSTHQYLSGVSKGEEPKILRPPRRPRKPKTLNNPEDSTYYYLLHKSTQEE--KRRPGKDSQGKLLGLEDFYYKEFLPT---------HYGPKAHSSNAR---EWKALKEPQAQPIESNERCWTTSENESLEEERISANPYDYRRLLRKTSQRQRLVQQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEV4-1", "uniprot_id": "MYO3A_HUMAN", "id": "Q8NEV4-1", "name": "Myosin-IIIa", "aln": "-----------------------------------------MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIH-------DIDEEIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCMGGTEK------------ARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNN----SFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRT--------------------SEKLIN------------------LAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQ---PHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQ---------KIQEKRKESAIIIQSAARGHLVRK-----------------------------QRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISAPN---NKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQ---EFYLVG---PEVSP-------KQKSVKDLEENSN----------LRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQE----EGRGRLRHETVKERQVEP------------------VTQAQEE--------EDKAAVFIQSKYRGYKRRQQLRKDK------------MSS-FKHQRIVTTPTEVARNTHNLYSYPTKHEEINNIKK-----KDNKDSKATSEREACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHH-KPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPKTLNNPEDSTYYYLLHKSIQEE--KRRPRKDSQGKLLDLEDFYYKEFLPS---------RSGPKEHSPSLR---ERRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEJ5-1", "uniprot_id": "A0AB32TEJ5_DANRE", "id": "A0AB32TEJ5-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------MSEDSCMHLWRSLGKMFPRSGKSIIFDSFPDPSDTWEIIETIGKGTYGKVYKVHNKVDGSKAAVKILDPIH-------DIDEEIEAEYNILKALSDHPNVVKFFGMFYKKDVKTGDQLWLVLELCNGGSVTDLAKGMLKRGDRMEEPIIAFILHEALMGLQHLHVNKTIHRDVKGNNILLTTDGGIKLVDFGVSAQLTNTRLRRNTSVGTPFWMAPEVIACEQQLDSTYDERCDVWSLGITAIELGDGDPPLAELHPMRALFKIPRNPPPTLHQPELWSNDFNDFIRKCLIKDFELRPNVLDLLQHVFIKQIVGREKTLQKQLMELIDLNQQMGIIEKTSLLGKSDRDSDSRHERIHTKKNSYMKSQSQTCDDADDLATLEVLDENTITEQLQRRYTKEQIYTYVGDILIAVNPFHKTELYTPEHTKSYVGAKRTSNPPHIYAVADIAYQSMVSYNADQCIVISGESGAGKTESAHLLVQQLTVLGKANNRTLQEKILLVNSLVEAFGNACTVINDNSSRFGKYLEMKFTCGGTVVGAQISDYLLEKSRVVHHAVGERNFHIFYYIYAGLAERKKLGHYKLSDSKTPRYLHNENVKLVPDIVGN----AFYKEQFETVEQCFKVIGFTLEELGSVYGILAGILNTGDVEFTSVASEHQTDKSNISNMAVLESAASLLCIRADELQEALTSHCVVTRGETIVRSNTVEKATEVRDAMGKALYGRLFSWIVNRINSLLKPDNQSGEDDKGLNIGILDIFGFENFKRNSFEQLCINIANEQIQFYFNQHIFAWEQDEYLNEDVDARVIEYEDNRPLLDLFLQKPMGMLSLLDEESRFPQATDQTLVEKFEDNLKSKNFWRPKRVDLGFGIHHYAGKVIYNAGGFLAKNRDALPADIVLLLRSSENELTRKLVTHPLTKTGNLAHTKGKAVGSARMGTQQSQRFAKLDCLLLFSSVSFSESSSRKLTPPIDKSMLALPVDSVQTTESTGDTTHHPRETTNMKTQTVASYFRYSLMDLLSKMVAGQ---PHFVRCIKPNNDRQAHKFDREKVLIQLRYTGILETAKIRRQGYSHRILFNNFIERYSILAFRANEEPAISPETCAVILEKAKLENWILGKTKVFLKYYHVEQLNLMVRQTTDRIVLVQAYVRGWMAFKRYC---------LLKEKREQSAVVLQSAYRGHKARKSIADDRSKAKSEIVFTQLQAWCRGYLARQNYKELLDEKNKAAAKIQAHYRGQKERKSFQRKKEAMQKENTEKTERVTEVPLEADDPVSEEPLQEGGEVEMDDADEKAAVVLQSNYRGYRERKKFKERQERNKTLSGDELDASSSTPEEMTSGEDLEATREDTQENVEKEGNEVEEGGGDEDPEQEAKAATVLQSNFRGHKERKRLQEEGKIPVRGKKEIKSPTDEEELPIPDPPPPEELMEFSEEMEFTEENPPGEEDEAKAAVVLQSNFRGHKERKRLQEEGKIPKKKTKEEMDDPGASEPDIAIEELPPPPLELEHDQELDSSPSGGDEEHAATVLQSNFRGHRERKRLRAEKEEATGGGQSTGDVEEQENNDVLDITDVQLERREEEEEGQYDEEQAAIKIQSNFRGYKDRKNLKATSQKQDEEVESLFKQVSKASEDYLSLQKKLNEIILAHQLNPSKNGMFVKGQPMNGYMGYYQPP------ADTKQSRTPRRAQQPKTLNTPEDSTYYTLIHRSVQDD--KRRPRKQSP-KKLDNDDQYYQGLSSSKSTSLPNERRRSSKRRASDERRSSERPLSDVPKSEIPKDPLEKRHSFSKMPSTESQSEDNPYDYRKILRKTSQRRRLITQP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10676-1", "uniprot_id": "NINAC_DROME", "id": "P10676-1", "name": "Neither inactivation nor afterpotential protein C", "aln": "----------------------------------------------MMYLPYAQLPDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKIQHYDE-------EHQVSIEEEYRTLRDYCDHPNLPEFYGVYKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYIIRETCRAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRGTCIGSPCWMAPEVVSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDVKTLYK-------------EPELFVDRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGN-RGATGRVESSIKAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRDIDFNHKQLETVRKVLAAILNIGNIRFRQNG-----KYAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPR--AVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKPDGLFYIIDDASRSCQDQDLIMDRVSEKHS----QFVKKHTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESER----------------------------------------------KSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKDNCRLLFLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKKVIKVQSMMRALLARKRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVR------------------------LPPLVNEKSGQLNENTADFIRPFAKKWREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQR-------------------------MVAGLNKCTRAVPFERINMREVNS-------------------------------------------------------------------------SQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPWDSPLQRNPSMTSCALTYNAYKKEQACQTNWDRMGE-----------------------------------SDNIYNQGYFRDPQQLRRNQMQMN-------------------------MNAYNNAYNSYNSNYNNQNWGVHRSGSRRNSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNYQQRSSYPPSDPVRELQNMARNEGDN-------------------SEDPPFNFKAMLRKTNYPRGSETNTYDFNNRRGSDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYG---------------------VSRKFGQQQRAPTLRQSPASVGRSFEDSNARSFEEAGSYVEEEIAPGITLSGYAVDI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.** . ::* * *.:*. .**::. : .. .*:*: . : : .:* **. *: .***: .*:*:: . .::*:*:* * **:..:: : :* . *: * *::*: : . .*: :: :***::*:*****.:* :** ***:* *: .: : .*.:*:* ******::. :. : *.*.*:****:***.**.**: ::** : :*:* ***.*.* :* *. .:..** :.* *: * ** : .::.* *:. . ::.:: .: : * . * : :**. *: : . *. : .:.***:::*. . :. : * .*: . ***:: ** .** :: * *::**** :**: .*:*::::* **..: : :: : : *: * :*::*:* : * * : ** :. *:*** ** ::*******:* : .:.:* :. **: .: :: .:. :: *.* ::: :: :**.*** *.:.* . . : : * :. * :* : .:: :**.. :*. * : * *.:.* .*** ..:**.**.. *:* ** :. : * *:**** *::*.:*** ** ***:*:::**::* * * *.:*. ::: ** . ** :* ** *:: ::*: ** : * : : : : * :.: **:* ::*.. .. *** .*.::: :*:* : :.. ***:***. . . : : : . :*::: **:: : **. : . **:***:.: : :. : : * *:: *:*:*. *: *:* *: : :*:.** *.: : . :.. :: : :: * :*:*****:**: * * : . ::: :*: :. : :* ::: .* :*.* * . * : .. : :. . . : : : . . : :. : .. :: : . : . : :* * :* *: . . ", "identical_positions": 277, "similar_positions": 390, "identity": "14.99%" }, { "cls_id": "homologset.agr.FB:FBgn0002939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97943-1", "uniprot_id": "SCRB1_RAT", "id": "P97943-1", "name": "Scavenger receptor class B member 1", "aln": "-MGVSSRARWVALGLGVLGLLCAALGVIMILMVPSLIKQQVLKNVRIDP-SSLSFGMWKEIPVPFYLSVYFFEVVNPSEVLN-GQKPVVRERGPYVYREFRQKVNITFNDNDTVSYIENRSLRFQPDRSQGSESDYIVLPNILVLGGAVMMEDKPTSLKLLMTLGLVTMGQRAFMNRTVGEILWG-YEDPFVNFLSKYFPDMFP--IKGKFGLFVGMNDSS--SGVFTVFTGVQNFSKIHLVDKWNGLSEVNYWHSEQCNMINGTAGQMWAPFMTPESSLEFFSPEACRSMKLTYQ-ESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCP-------CRESGIQNVSTCRFGAPLFLSQPHFYNADPVLSEAVLGLNPDPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPVVLPLLWFEQSGMMGGKTLNTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIIYQLRSQE-----------KCFLFWSG-----------------------SKKGSQDKEAMQAYSESLMSPAAKGTVLQEAKL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61009-1", "uniprot_id": "SCRB1_MOUSE", "id": "Q61009-1", "name": "Scavenger receptor class B member 1", "aln": "-MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDP-SSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLN-GQKPVVRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWG-YDDPFVHFLNTYLPDMLP--IKGKFGLFVGMNNSN--SGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYN-ESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCP-------CRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIICQLRSQE-----------KCFLFWSG-----------------------SKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTV0-1", "uniprot_id": "SCRB1_HUMAN", "id": "Q8WTV0-1", "name": "Scavenger receptor class B member 1", "aln": "-MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDP-SSLSFNMWKEIPIPFYLSVYFFDVMNPSEILK-GEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWG-YKDPLVNLINKYFPGMFP--FKDKFGLFAELNNSD--SGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYK-ESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCP-------CLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRTLWPTAAWSPPPAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLEGLGPSLGGGTGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z8R4-1", "uniprot_id": "A0A8M6Z8R4_DANRE", "id": "A0A8M6Z8R4-1", "name": "Scavenger receptor class B member 1", "aln": "-MVSQTTVSIVFLVLGGMALLF---GTVLVFVGPIIIDDQIVKNVEINPKNDLSYTMWKDIPVPFFMSVYFFHIVNPDEILK-GERPMVIQRGPYVYRENRWKDNITFHENHTVSYKEYRQYFFEESMSVGDESDVVTIPNMLVLGASVMMENMPFPVRLLLSTTFKTFNEGPFLTKPVGELMWG-YDSKLVDFLNKYLPGMLP--SSGKFGLFADFNNSN--TGLFTIFTGRDDIRKVHMVDSWNGLKNVDYWRSDQCNMINGTAGQMWPPFMTKETTMPFYSPDACRSMELVYQ-RPLVSSGIPVYRYVSPKTLFANGADFPPNEGFCP-------CRQSGLLNVSSCRHGSPTFISQPHFYNADPQLLDTVSGLSPSEDEHGLFIDIHPETGVPVNVSVRLQLNLFLKKVSGISETGNIAEVVMPMLWFEESGYIDGPVLHTFRTNLVVLPKVMEYMQYIFIALGLAAILTAVILFLTDKK---------------VWKK-----------------------SSQTLTQAVSTRVYDNVNHSKQHPANETQAEKYNQSNTGKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INY3-1", "uniprot_id": "Q8INY3_DROME", "id": "Q8INY3-1", "name": "", "aln": "MCCSCCGVTQQKAWVFGLGTFFAVSGLLAIICWPGFIDSGIMKALPLTP-TSKTFEKWEELPIPVYVYMYLWNWTNAADVQANGVKPIFAQLGPYVYREERKKMDLEWHDNGTVTFNPRRTWFWEEELSGGKQTDLITAPHLPSLAASNQMRNSNVFLKFMFNEALNANGGHLFVTHTAAEWLFESFYDEFLHYAMTLNNPLVPKIESDHFAWFLNRNGSKDFEGPFTVHTGVGDIKEMGEIKYWKGQNHTG-WYDGECGRLNGSTTDLFVPDEPKEKALTIFIPDTCRIINLEFTGQSETIQGITGWKYEITPNTFDNGQINGNAKCWCPLERQPDNCPATGATDLGPCADGVPMYLSADHFMYADESYGSTISGYNPNYDQNNFYIIMERKMGVPLKVNANVMITLYIEPDSVIDILKGLPSFYAPLFTTASRAEIDEALASELRLALN-LPAIGRYTGVGFLCLGCILIAVGILLTIKRKW------------------------------------------YGQAELDKLALKDNEETPYEPEVPANVVERNF----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * : :. * :*.. ::* : : * .. :: *:::*:*.:: :*::. *. :: * :* . : ******* * * :: :::* **:: * :: . * *.::* :. *:: *..: *.. :::::. : : . *:.:...* :: : . ::. . :.* ..:*. * *.*. * **:.** :: .: :. *:* .. . * . :*. :**:: ::: * . *.:: :: *::** ::* : .. . .**. ::: . . * ** : :** * :* ::..* . * ::* ** ** .:: * *. . :.::: :. *:*:: ...: :.*::: :. : . *:: . . : : * :* : .* :: ** : . :: : : . . . : ", "identical_positions": 82, "similar_positions": 189, "identity": "14.44%" }, { "cls_id": "homologset.agr.FB:FBgn0002940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R456-1", "uniprot_id": "OPN4_RAT", "id": "Q8R456-1", "name": "Melanopsin", "aln": "-MN--SPSESRVPSSLTQDPSFTASPALLQGIWNSTQN-ISVRVQLLSVSPTTP--GLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRAC-EGCGESPLR-RRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLS-YRSTHRSTLSSQSSDLS----WISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFC-----------------------------------SHDLEDGEVKAPSSPQEQKSKTPKT----------------------KRHLPSLDR-----RM---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ9-1", "uniprot_id": "OPN4_MOUSE", "id": "Q9QXZ9-1", "name": "Melanopsin", "aln": "-MD--SPSGPRVLSSLTQDPSFTTSPA-LQGIWNGTQN-VSVRAQLLSVSPTTS--AHQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRAC-EGCGESPLRQRRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSGQRSHPSLS-YRSTHRSTLSSQSSDLS----WISGRKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFC-----------------------------------SQNLEDGELKASSSPQVQRSKTPKVPGPSTCR-----------PMKGQGARPSSLRGDQKGRLAVCTG--------------LSECPHPHTSQFPLAFLEDDVTLRHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHM6-1", "uniprot_id": "OPN4_HUMAN", "id": "Q9UHM6-1", "name": "Melanopsin", "aln": "-MN--PPSGPRVPPSPTQEPSCMATPA-PPSWWDSSQSSISSLGRLPSISPTAP--GTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRAL-QTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPS-YRSTHRSTLTSHTSNLS----WISIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLY-----------------------------------GQGLEDLEAKAPPRPQGHEAETPGKT---------------------KGLIPSQDP-----RM---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2KNE5-1", "uniprot_id": "OPN4A_DANRE", "id": "Q2KNE5-1", "name": "Melanopsin-A", "aln": "MMSGAAHSVRKGISCPTQDPNCTRIVESLSAWNDSVMS-AYRLVDLPPTTTTTTSVAMVEESVYPFPTVDVPDHAHYTIGAVILTVGITGMLGNFLVIYAFSRSRTLRTPANLFIINLAITDFLMCATQAPIFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLMVIAVDRYFVITRPLASIGVLSQKRALLILLVAWVYSLGWSLPPFFGWSAYVPEGLLTSCTWDYMTFTPSVRAYTMLLFIFVFFIPLIVIIYCYFFIFRSIRTTNEAVGKINGDNKRDSMKRFQR--LKNEWKMAKIALIVILMYVISWSPYSTVALTAFAGYSDFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRLAIAKYIPCLRLLLCVPKRDLHSFHSSLMSTRRSTVTSQSSDMSGRFRRTSTGKSRLSSASDSESGWTDTEADLSSMSSRPASRQVSCDISKDTAEMPDFKPCNSSSFKSKLKSHDSGIFEKSSSDVDDVSVAGIIQPDRTLTNAGDITDVPISRGAIGRIPSIVITSESSSLLPSVRPTYRISRSNVSTVGTNPARRDSRGGVQQGAAHLSNAAETPESGHIDNHRPQYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06002-1", "uniprot_id": "OPS1_DROME", "id": "P06002-1", "name": "Opsin Rh1", "aln": "------------------MESFAVAAAQLGPHFAPLSNGSVVDKVTPDMAHLIS------PYWNQFPAMDP--IWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEG-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCC----------------------------------------VFGKVDDGKSSDAQSQATASEAESKA-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . :*::* : : :: :*: . ** *** *. .: ******:::****::** : *::*:: . .: *::* *.:** *: ** *: :: *::*** **.: :* : : : *. : *.*.* **** ***** **** **: *:* :: **:::**::* :.* **: :: .* : : . * *:**: *:.* ::.::*:** .: .: : *** . * :**::* :***:*.*:***** *: : ** : . .*::: * *: ", "identical_positions": 101, "similar_positions": 100, "identity": "16.95%" }, { "cls_id": "homologset.agr.FB:FBgn0002941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R5R8-1", "uniprot_id": "M0R5R8_RAT", "id": "M0R5R8-1", "name": "NK1 transcription factor-related protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGRAELPIFPRAGVPPLAVSDTVPAVP--DGAGAARPAAPPRPTSFSVLDILDPNKFNSRRRRCVLLGPVVPATCAPCAPAACVPVPAASGRSPR-AELERRALSAATGVAAATGAEPTSTGDSYR----------------------------ADEAEAN---GYSSGSG-RSPTADSEDEAPEE-DEDEDQAPEVQDVQGTEEPRGGSGGLGARGSGCSGAAEVEASP-----------------------------------------------------VDEAAAPGPRGNSPGAPGPPVTAAGAGNAGSTPQGAAVATKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGAGLPGGLSPLSPSPPMGAPLALHGPAGYPAHSPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAPAFYAPHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UXB3-1", "uniprot_id": "NKX11_MOUSE", "id": "G3UXB3-1", "name": "NK1 transcription factor-related protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTSGPAAPGDVPALPPPPPGPGSGPAPPAPAATARDTMDGRAELPIFPRAGVPPLAASDTVPAVP--EGAGAARPAAPPRPTSFSVLDILDPNKFNSRRRRCVLLGPVVPATCAPCAPAACVAVPAASGRSPR-AELERRALSAATGVAAAAGAEPTSAGDSYR----------------------------ADEAEAN---GYSSGSG-RSPTADSEDEAPE--DEDEEEAPEVQDAQGTEEPRGGSGGLGARGSGCPGAAEVEASP-----------------------------------------------------VDDTAAPGPRGNSPGAPGPPATATGAGSAGSTPQGAAVTTKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGAGLPGGLSPLSPSPPMGAPLALHGPAGYPAHSPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAPAFYAPHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15270-1", "uniprot_id": "NKX11_HUMAN", "id": "Q15270-1", "name": "NK1 transcription factor-related protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASGPEAPGDIPALPPPPQ-PGSGPAPPAPAAAAQEAMDGRAELPAFPRAGAPPLAASDTVPAAP--EGAGAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGRPPRAEELERRALAGAGGVGAAG-AEPPNAGDPFK----------------------------AGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPG--------------------------------------------------ATVDEAAAPGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAPAFYAPHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q75W95-1", "uniprot_id": "NKX11_DANRE", "id": "Q75W95-1", "name": "NK1 transcription factor-related protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MNREKVQVGDSVAP-------AGAGVIVVAPQDGMDDKRLAAGELPVFNCVGGRDALPAESRETSPRHEPVPAGAPPTVHRTTSFSVLDILDPNKFTSKRQ--------TPNRTG------CEFAFGAENRSDD-SNHTIEHKSYQEDYDCKKTSGILKDGFVFR----------------------------SDECESD----FTRGNQ-----SDS----------------ELQEDLCSEESSALTGNNDAEFGQHEDDDSISKSP----------------------------------------------------------------------------DGQQTQQSSSNGQNHQVKPKRKRSGSDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTSGGGG---GNGPSNGL-GGLSPLSPSPPMSGHLSMH--TSYPGHTPGGLVCTTQLPFLPGHAVLSPFMLGSQTYGAPTFYAPHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9UD57-1", "uniprot_id": "NKX12_HUMAN", "id": "Q9UD57-1", "name": "NK1 transcription factor-related protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAWQDGG---------------------AKAAPSHHKISFSVLDILDPQKFT-------------------------RAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLETPDAAG----------------------------PGAGQAS----PLEGSE-----AEE-----------EEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPC---------------------------------------------------------------------------EDGGGGPVRSPPGSPGSPRPRRRR--LEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQP---GAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAAN-VLFPSAASFP-LTAAAPGSPFAPFLGPSYLTPFYAPRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42580-1", "uniprot_id": "NKX12_MOUSE", "id": "P42580-1", "name": "NK1 transcription factor-related protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAWQDVG---------------------AKAAPSHHKISFSVLDILDPQKFT-------------------------RAALPPVRLAALEAKKSLEEVEAGQDACSGNPIGSQETPDAVG----------------------------RGIDPGS----PVEGSE-----AEE-----------EEEAEDAGRAHQPERWQGVHEG---SPEARAVAVGTEESG---------------------------------------------------------------------------AEG----LPASPGSPGSPRPRRRR--AESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAVQAGGGAPQPGTPGAVAGGGGSATGSSPGPPVPGALPYQTFPTYPATN-VLFP-AASFP-LTTAANGSPFTPFLGPSYLTPFYAPHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22807-1", "uniprot_id": "SLOU_DROME", "id": "P22807-1", "name": "Homeobox protein slou", "aln": "MVMLQSPAQKASDSASAQNTAVGGLMSPNSNPDSPKSNTSPDVASADSVVSGTGGGSTPPAAKIPKFIISANGAAVAGKQEQELRYSLERLKQMSSESGSLLSRLSPLQEDSQDKEKPNHNNNNSLTNHNANSNTRRSQSPPASVGSVSFSSPAQQRKLLELNAVRHLARPEPLQHPHAALLQQHPHLLQNPQFLAAAQQHMHHHQHQHHQHPAHPHSHQHPHPHPHPHPHPHPSAVFHLRAPSSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQNPPHSSQPPQQQQVAAPSDMDLERIKLVAAVAARTTQASSTSALASASNSVSNASISISNSSSGSPSGRDLSDYGFRIQLGGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHSTPSVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHPRQWSYERDEEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDVNSPT------------------------IPPPGGGSFGPGAYASGLLYS--------------HAVPYPPYGPYFHPLGAHHLSHSHS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... . .. . *.* . . . . . . : . : . . : . : .***************:*****::**************************************** * . ** . : . . .*: . : .: ", "identical_positions": 66, "similar_positions": 37, "identity": "9.47%" }, { "cls_id": "homologset.agr.FB:FBgn0002945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A182-1", "uniprot_id": "D4A182_RAT", "id": "D4A182-1", "name": "Protein naked cuticle homolog", "aln": "-------------MGKFQSKHGEEPAGGRERGSGWAPPLTVPSLFPVSSDRAAAAAACKRRESPEGDSFVVS-AYASGRKGAEETDRRA------------GSGVEHRARDKQELPNGDPKEGPFWEDK--GSLEVVLPPEKSEGHEG--QLFSVDDGEKAANREGPLRLSKKHLNIDALQCDVSVEEDNRQE---WTFTLYDFD-NSGKVTREDMSSLMHTIYEVVDASVNHSSGSSK-TLRVKLTVSPEPSSK-KEWLPP------------------------------------------------------------GQEREPTRGRTESELPDDPRVADRRLSAYSRKPNTDPQPCPVRVPYCVDENTERRNHYLDLAGIENYTSKFG-----PGSPPEQARQEHHGRATHIPSRSRSQESDAHAIHHRRSQVLAEHIVP-ANEPAPRALAAQPRLKGQE---KQFLRSPKGPGKPLG-APSGSKPGKSLSHCLQAVPLS--QGAQDGHHLPQPPPQPPPQPYGHKRYRQKSREGHSPLKG------HGQPTMVEHEVVRD----------------------------------------LPPMLGPEGYVVP-------------------------MIQRHEHHHHHEHHHHHHHHHFHPNAS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE28-1", "uniprot_id": "NKD2_MOUSE", "id": "Q8VE28-1", "name": "Protein naked cuticle homolog 2", "aln": "-------------MGKFQSKH--------------------------------AAAACKRRESPEGDSFVVP-AYGSGRRGAEETDRRA------------GSGVEHRSRDKQELLNGDPKEGPFWDDK--GSLEVVLPPEKSEGHEGQGQLFSTDDGEKAASREGPLRLSKKHLNIDALQCDVSVEEDNRQE---WTFTLYDFD-NSGKVTREDMSSLMHTIYEVVDASVNHSSGSSK-TLRVKLTVSPEPSSK-KECPLT------------------------------------------------------------GQDREPTRGRTEIELTDEPRVADRRLSAYSRKPNADPQPCSVRVPYCVDENTERRNHYLDLAGIENYTSKFG-----PGSPPEQARQEHHGRATHIPSRSRSQESDAHAIHHRRSQVLAEHVIP-ANEPATRALAAQPRIKGQE---KQFLRSPKGPGKPLG-TPGSGKPGKALSYCLQAVPLP--QSAQDGHHLPQPPPQPPPQPYGHKRYRQKAREGHSPLKG------HGQPTMVEHEVVRD----------------------------------------LPPMLGPEGYVMP-------------------------VVQRHEHHHHHEHHHHHHHHHFHPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969F2-1", "uniprot_id": "NKD2_HUMAN", "id": "Q969F2-1", "name": "Protein naked cuticle homolog 2", "aln": "-------------MGKLQSKH--------------------------------AAAARKRRESPEGDSFVAS-AYASGRKGAEEAER--------------------RARDKQELPNGDPKEGPFREDQ--CPLQVALPAEKAEGREHPGQLLSADDGERAANREGPRGPGGQRLNIDALQCDVSVEEDDRQE---WTFTLYDFD-NCGKVTREDMSSLMHTIYEVVDASVNHSSGSSK-TLRVKLTVSPEPSSKRKEGPPA------------------------------------------------------------GQDREPTRCRMEGELAEEPRVADRRLSAHVRRPSTDPQPCSERGPYCVDENTERRNHYLDLAGIENYTSRFG-----PGSPPVQAKQEPQGRASHLQARSRSQEPDTHAVHHRRSQVLVEHVVP-ASEPAARALDTQPRPKGPE---KQFLKSPKGSGKPPG-VPASSKSGKAFSYYLPAVLPP--QAPQDGHHLPQPPPP----PYGHKRYRQKGREGHSPLKAP-----HAQPATVEHEVVRD----------------------------------------LPPTPAGEGYAVP-------------------------VIQRHEHHHHHEHHHHHHHHHFHPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4ZNR4-1", "uniprot_id": "NKD2_DANRE", "id": "A4ZNR4-1", "name": "Protein naked cuticle homolog 2", "aln": "-------------MGKLHSKH-----------------------------------ACKRRENPEGDSFVVN-GFIAKR-AAEEGER--------------------YGNNLKDYKNEELKDSQPTLLH--CPLQVVLPPEKAEGCESFLQYLSPDDEERDAQK------VTKRISLQDLECNVSLAEDNRQE---WVFTLYDFD-NSGKVTKEDMSSLMHTIYDVVDASVKHSCNSKRRSLRVKLSVTPEPAARRRDATHT------------------------------------------------------------ERETS-HLSQVEPVRSEEHRSADRRQSTHIRG-QTEAHEGN---HYCVDENTERRNHYLDLAGIENYTSRFD-----SSSP--DADQDPPSRSSHSQSRPHSQEPETH-VYQRRSQLMEPCVAP-DPR-----LRTGPQLIRS--------RSPKGSSRYPGVIPNVTKTSKCHGHHQPIS------AGQDVYHLTQ----------------QSHTHAHTPSGLQ-----HSHSRRIRSRAREQ----------------------------------------QALTPVKNTNATA-------------------------LVQRHEHHHHHEHHHHHHYHHYHQT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4ZNR5-1", "uniprot_id": "NKD2L_DANRE", "id": "A4ZNR5-1", "name": "Protein naked cuticle homolog 2-like", "aln": "-------------MGKLHSKH-----------------------------------ACKRRENPEGDSFVVN-GFIAKR-AAEEDER--------------------YGNNLKDYKNEELKDGRLTLLH--CPLQVVLPPEKAEGCESFLQYLSPDDGERDAQK------VKKRISLQDLECNVSLAEDNRQE---WVFTLYDFD-NSGKVTKEDMSSLMHTIYDVVDASVKHSCNTKRRSLRVKLSVTPEPAARRRDATHT------------------------------------------------------------ERETS-HLSQVEPVRSEEHRSADRRQSTHIRG-QTEAHEGN---HYCVDENTERRNHYLDLAGIENYTSRFD-----SSSP--DADQDPPSRSSHSQSRPHSQEPETH-VYQRRSQLIEPCVAP-DPR-----LRTGPQLIRS--------RSPKGSSRFPGVIPNVTKTSKCHGHHQPIP------TGQDVYHLTQ----------------QNHTHAHTPSGLQ-----HSHSRRIRSRAREQ----------------------------------------QALTPVKNTNATA-------------------------LVQRHEHHHHHEHHHHHHYHHYHQT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q969G9-1", "uniprot_id": "NKD1_HUMAN", "id": "Q969G9-1", "name": "Protein naked cuticle homolog 1", "aln": "-------------MGKLHSKP---------------------------------AAVCKRRESPEGDSFAVS-AAWARKGIEEWIGRQR--CPGGVSGPRQLRLAGTIGRSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKKMERVSEPCPGS-------KKQLKFEELQCDVSMEEDSRQE---WTFTLYDFD-NNGKVTREDITSLLHTIYEVVDSSVNHSPTSSK-MLRVKLTVAPDGSQSKRSVLVN------------------------------------------------------------QADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLEQSGCYHHCVDENIERRNHYLDLAGIENYTSQFG-----PGSPS-VAQKSELPPRTSNPTRSRSHEPEAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKSVG-VGHVARGARNKPPLGPAIP----AVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPLASGG-PVLGREHLRE----------------------------------------LPALVVYESQAGQ-------------------------PVQRHEHHHHHEHHH--HYHHFYQT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MH6-1", "uniprot_id": "NKD1_MOUSE", "id": "Q99MH6-1", "name": "Protein naked cuticle homolog 1", "aln": "-------------MGKLHSKP---------------------------------AAVCKRRESPEGDSFAVS-AAWARKGIEEWIGRQR--CPGSVSGPRQLRLAGTVGRGTRELVGDTSREALGEEDEDDFPLEVALPPEKIDSLGSGDEKRMERLSEPGQAS-------KKQLKFEELQCDVSVEEDSRQE---WTFTLYDFD-NNGKVTREDITSLLHTIYEVVDSSVNHSPTSSK-TLRVKLTVAPDGSQSKRSVLFN------------------------------------------------------------HTDLQSTRPRADTKPAEELRGWEKKQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFG-----PGSPS-VAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKNMG-MGHGARGARSKPPLVPTTH----TVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQGPLAAGGSTVMGREQVRE----------------------------------------LPAVVVYESQAGQ-------------------------AVQRHEHHHHHEHHH--HYHHFYQP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TJA6-1", "uniprot_id": "NKD1_DANRE", "id": "Q2TJA6-1", "name": "Protein naked cuticle homolog 1", "aln": "-------------MGKLHSKH---------------------------------AAICKARESPEGDSFVVN-ACLARKGLDDWMVKQKYYCSSSRVDQRDCQQKNNCELSPRDPLDEGYAEGISDEH---YRLEVALPPEKTDSC-SVEERMQGTEGSATVGP-------HKQLQFEELECAVSVEEDNRQE---WTFTLYDFD-NNGKVTREDITSLLHTIYEVVDASVNHSPSSSK-TLRVKLSVAPDSSQRWKNCTQT------------------------------------------------------------NTDTPNPKHKGE-KCIEDSKTSEKKSRAFLRRYHAEHHSQQGCQRHCVDENLERRNHYLDLAGIENYTSRFG-----TAAPATEPAKPTHATRSSNQSRSRSQEPENGQ--------VHPAHHRRSQTMSTDPPAILTRHT-------HALRSPKTHRTPPT-QASAGRVMRRGAPPPPSVP----NQTP-PHQSSGP----------YRRHKQRPKEALH-YRALGPSVTSGP--VLEKEHVRD----------------------------------------LPSLVLYEGGLAQ-------------------------VVQRHEHHHHHEHHH--HYHHFYQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVV9-1", "uniprot_id": "NKD_DROME", "id": "Q9VVV9-1", "name": "Protein naked cuticle", "aln": "MAGNIVKWWKHKILGGYKQFSVQECTTDSEELMYHQVRASSSCSAPPDLLLVSERDNNIQLRSPVVNIITTPPGNASGAGSKQQSHHQTNHHSSGRSHPGHTAHPQDVSSGGSHSKHLRISSTSNGKHGKYSNMQQQLPQDEDVVDAAATMQQQQHTGHAHSRHLHHHK--EERIRLEEFTCDVSVEGGKSSQPLQFSFTFYDLDGHHGKITKDDIVGIVYTIYESIGKSVVVPHCGSK-TINVRLTVSPEGKSKSQPVVPVPVAAGFSSSHASKLKKLPTGLAAMSKPLAGGGVGSGGASALTTSAGNRRQHRYRPRKLIKSDDEDDDSNSEKEKDAAHAPAADQPSGSGTKATGKSHHHQSQSARYHQKNNSRAEQCCTEQNTPDNGHNTYENMLNLKCCKPEVDQVDCPSHRQHHQSHPNHQMRQQDIYMKQATQRVKMLRRARKQKYQDHCLETRQRSLSVGNDSACPNRHLQLQQPPVGHPQPQSLNHKSASGSPPLGVGGGGDMMLDGVQLRQPRPHSLTPHQHQQQNQQQQQQQRKSAECWKSALNRNDLISIIRESMEKNRLCFQLNGKPQANVSPIRQPAAQQQPQQQQRQRCNTGSKIPTLITNHSPVAQQSPLSCSPPTAEPTTPSIPAAPPAIEVNGQQHHPTHPTHPSHHNHHEHPQPHIPIYHQQLAINPAVLAAQQTHNTAHNKLNLCGYDSFLHATICGGGAAAHSPPATPSNVATVQPIPKKSQKNLLQGYQRLEQSQQQQQQQRSSKDYKNYGNLIYAKLSEQLQQKDREQRRQRHKQQQHQMLQDQPKDASRSEQRPPTSNSSSAGSKIYGDAVECAHLLASEEEDLPPSPQLTSTPSKVVSTDTLIDLNDDVGEAVAEAVTEGGKQSLEAEESGQQVEVELDTSASSSMIHRYVHEHIHHHYHHFKEQQDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. ..* : :.. . : : : . . . :: ** :: ::: :: : * **: .. .: : **:**:* : **:*::*: .:::***: :. ** . .: :.*:*:*:*: : : . . :: : : . : .:* . .: : :* . : . ::.. : : : : : : : : . : . .. . . :: ::** * * * ** : ", "identical_positions": 34, "similar_positions": 99, "identity": "3.65%" }, { "cls_id": "homologset.agr.FB:FBgn0002962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVJ1-1", "uniprot_id": "A0ABK0LVJ1_RAT", "id": "A0ABK0LVJ1-1", "name": "", "aln": "------------------------------------------------------------------MEAFPWAPRSPRRARAPAPMALVPSARYVSASGPVHPQPFSYWN----------------DYLGLATLITRASD--------RG-----------------SPHEGPGPTPAGPTLGPP--EDDEDDDGDEPEAGGRYLGGALELRALELCAGPAEAGLLEERFAELNPFAGRAAAVLLGCAPSAS--------------------------------------------AASTAEVTPREEPSPAWAAEPRLHATSGATAARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKVPPPTVRPPPRSTRDNLPSKKLR-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WY3-1", "uniprot_id": "NANO1_MOUSE", "id": "Q80WY3-1", "name": "Nanos homolog 1", "aln": "------------------------------------------------------------------MEAFPWAPRSPRRARAPAPMALVPSARYVSASGPVHPQPFSSWN----------------DYLGLATLITRASD--------RG-----------------SPHEGPGPTAAGPTMGPP--EDDEDDDGEEPEAGGRYLGGALELRALELCAGPAEPGLLEERFAELNPFAGRAAAVLLGCAPTASTT----------------------------------------AAAASTAEVTPREEPSPAWAAEPRLHAASGATAARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKVPPPTVRPPPRSNRDSLPSKKLR-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WY41-1", "uniprot_id": "NANO1_HUMAN", "id": "Q8WY41-1", "name": "Nanos homolog 1", "aln": "------------------------------------------------------------------MEAFPWAPRSPRRGRAPPPMALVPSARYVSAPGPAHPQPFSSWN----------------DYLGLATLITKAVDGEPRFGCARGGNGGGGSPPSSSSSSCCSPHTGAGPGALGPALGPPDYDEDDDDDSDEPGSRGRYLGSALELRALELCAGPAEAGLLEERFAELSPFAGRAAAVLLGCAPAAA------------------------------------------AAATTTSEATPREERAPAWAAEPRLHAASGAAAARLLKPELQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLSKVPPPPARPPPRSARDGPPGKKLR-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDB3-1", "uniprot_id": "NANO1_DANRE", "id": "E7FDB3-1", "name": "Nanos homolog 1", "aln": "-------------------------------------------------------------------------------------MDFLNHN-YLSAR-ASYDYTFNFWN----------------DYLGLSTLVTKNSK----------------------------HSVPQNPNSITESLKAT---LGLDDSPPCPCVMGEGDSGGHLDSCCCPPPASISILDLKERFSILSPFQNQNQGSLLSSSQERE------------------------------------------------IGIGGGFAGFDLFGVERKMRKP-----AARNKQEPKICVFCRNNGAPEEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKDQPAQRVLKGGRAVGGKRVKIF--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90WW1-1", "uniprot_id": "NANO3_DANRE", "id": "Q90WW1-1", "name": "Nanos homolog 3", "aln": "-----------------------------------------------------------------------------------MAFSLLQFILSAHGSMETRNQDFQPWK----------------DYMGLADMIRGMKR---------------------------------------------------------QEMQSDADSDEQAAALLESPSGPIRSRDSPEQNTSPGGGKPKSS------------------------------------------------------------------------------------------PAERKFCSFCKHNGETEAVYTSHYLKNRDGDVMCPYLRQYKCPLCGATGAKAHTKRFCPMVDKNYCSVYAKSTW------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A138-1", "uniprot_id": "D4A138_RAT", "id": "D4A138-1", "name": "", "aln": "PGVPTCVAATPFVRRAYAPRPPAHLPCLWPACLCARVLLPRLEGCVQPRSLPAPRVPLELQPGAPGLAGGPGRARPQLDPPAGAARGPRGRGRVAAGSNLSVLSRAGGWVGYGTPAERRALRRQRRDYLGLARLVGALHE------------------------------------------------------------------EEEPDVRLDPKPEPKPSSAS-QQASKESS------------------------------------------------------------------------------------------------AAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTGQGYTSVYCYTTRNSAGKKLTRPDKAKTQNAGHRLGGEAAA----GSKSGRKPPGPSPSACCPSTTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60324-1", "uniprot_id": "NANO3_MOUSE", "id": "P60324-1", "name": "Nanos homolog 3", "aln": "------------------------------------------------------------------------------------------------------MGTFNLWT----------------DYLGLARLVGALHK------------------------------------------------------------------EEELDVRLDPKPEPKPSSES-QQASKESS------------------------------------------------------------------------------------------------AAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTSQGYTSVYCYTTRNSAGKKLTRPDKAKTQDAGHRLGGEAAAGVYAGSKSGRKPPGPSPSACCPSTTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60323-1", "uniprot_id": "NANO3_HUMAN", "id": "P60323-1", "name": "Nanos homolog 3", "aln": "------------------------------------------------------------------------------------------------------MGTFDLWT----------------DYLGLAHLVRALSG------------------------------------------------------------------KEGPETRLSPQPEPEPMLEPDQKRSLESS------------------------------------------------------------------------------------------------PAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATRERAHTRRFCPLTGQGYTSVYSHTTRNSAGKKLVRPDKAKTQDTGHRRGGGGGAG---FRGAGKSEPSPS---CSPSMST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0L7C2-1", "uniprot_id": "A0ABK0L7C2_RAT", "id": "A0ABK0L7C2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MDLPPFDRWR----------------DYFNLSQVVLGIIQ------------------------------------------------------------------SRKQRLEDEVSEELASRPQGMSERGLEVS-----------------------------------------------------------------------------------------------PGSLATACNFCKHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCPLNSS-QQSLYRRSGRNSAGRRVKR---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60322-1", "uniprot_id": "NANO2_MOUSE", "id": "P60322-1", "name": "Nanos homolog 2", "aln": "----------------------------------------------------------------------------------------------------MDLPPFDMWR----------------DYFNLSQVVMDIIQ------------------------------------------------------------------SRKQRQEGEVAEEPNSRPQEKSEQDLEGY-----------------------------------------------------------------------------------------------PGCLPTICNFCKHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCPLNSS-QQSLYRRSGRNSAGRRVKR---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60321-1", "uniprot_id": "NANO2_HUMAN", "id": "P60321-1", "name": "Nanos homolog 2", "aln": "----------------------------------------------------------------------------------------------------MQLPPFDMWK----------------DYFNLSQVVWALIA------------------------------------------------------------------SRGQRLETQEIEEPSPGPPLGQDQGLGAPGA---------------------------------------------------------------------------------------------NGGLGTLCNFCKHNGESRHVYSSHQLKTPDGVVVCPILRHYVCPVCGATGDQAHTLKYCPLNGG-QQSLYRRSGRNSAGRRVKR---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25724-1", "uniprot_id": "NANOS_DROME", "id": "P25724-1", "name": "Protein nanos", "aln": "------MFRSNLEGSGAAAVGVANPPSLAQSGKIFQLQDNFSAFHARGGLNILGLQDMYLDTSGANSSATLSPPITPVTPDPSTSAQSTHFPFLADSAATANSLLMQRQYHYHLLLQQQQQLAMAQHQLALAASAAAASASHQQTDEIAR-------------SLKIFAQVTTGAAENAAGSMQDVMQEFATNGYASDDLGRMSYGSAPPQVQMPPQQQHQQQQGLHLPLGRNPAQLQTNGGNLMPIPLATHWLNNYREHLNNVWRNMSYIPAAPNTMGLQAQTAATVSTNLGVGMGLGLPVQGEQLRGASNSSNNNNNNNKVYKRYNSKAKEISRHCVFCENNNEPEAVINSHSVRDNFNRVLCPKLRTYVCPICGASGDSAHTIKYCPKKPIITMEDAIKAESFRLAKSSYYKQQMKV---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: * **.:* . : :* :: . *:** ** * ** *.*. *** ::** ", "identical_positions": 21, "similar_positions": 16, "identity": "4.58%" }, { "cls_id": "homologset.agr.FB:FBgn0002973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1I3-1", "uniprot_id": "NUMBL_RAT", "id": "A1L1I3-1", "name": "Numb-like protein", "aln": "MSRSAAASGGPRRPDQHLPPAPCGASGPPETFRTESDGAGTMNKLRQSLR---RRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAM-----------GRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAGDKKKAEAAAAP---AVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGTGDSDGISALCTQISSSFASA------GAPVPGPPSATTGTS-------------------------------------------------------AWGEPS-VPAATAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQQQQQQATSVPPMPTMAPTLQPFS-TPVGPFDTAAAQVAVFLPPTHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPTAPSAPGG-----QARPRPNGAPWP------------PEPAPAPAPELDPFEAQWAALEGKP---AVEKPSNPFSGDLQKTFEIEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08919-1", "uniprot_id": "NUMBL_MOUSE", "id": "O08919-1", "name": "Numb-like protein", "aln": "MSRSAAASGGPRRPDQHLSPAPCGASGPPETFRTESDGAGTMNKLRQSLR---RRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAM-----------GRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAGDKKKAEAAAAP---AVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGTGDSDGINALCTQISSSFASA------GAPASGPPPATTGTS-------------------------------------------------------AWGEPS-VPAAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQ----------QATSVPPMPTMAPTLQPFS-APVGPFDTAAAQVAVFLPPTHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPAAPSAPGG-----QARPRPNGAPWP------------PEPAPAPAPELDPFEAQWAALEGKP---AVEKPSNPFSGDLQKTFEIEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6R0-1", "uniprot_id": "NUMBL_HUMAN", "id": "Q9Y6R0-1", "name": "Numb-like protein", "aln": "MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLR---RRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAM-----------GRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAP---TVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASA------GAPAPGPPPATTGTS-------------------------------------------------------AWGEPS-VPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQ-----QAASVAPVPTMPPALQPFP-APVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPAIPSAPGS-----QARPRPNGAPWP------------PEPAPAPAPELDPFEAQWAALEGKA---TVEKPSNPFSGDLQKTFEIEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2LC84-1", "uniprot_id": "NUMB_RAT", "id": "Q2LC84-1", "name": "Protein numb homolog", "aln": "-----------------------------------------MNKLRQSFR---RKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDAKKAETDKT-VGPSVAPGNSAPSPS--SPTSPTLDPTASLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNTVPEVE----GEAESISSLCSQITSAFSTPCEDPFSSAPMTKPVTLVAPQSPVLQANGTDSALHVLTAKPASTALAPVAMPVRETNPWAHAPDAANKEIAAIHSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ-------------PPPPAAIAPPAPPFQGHAFLTSQPVPVGVVPPLQPAFVSTQSYPVANGMPYP-ASNVPVVGITPSQMVANVFGTAGHPQATHPHQSPSLAKQQTFPQYETSSATTSPFFKPSAQHLNGSAAFNGVDNSGLVSGNRPAQVPPGTCPVDPFEAQWAALESKPKQRTNPSPTNPFSSDAQKAFEIEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS3-1", "uniprot_id": "NUMB_MOUSE", "id": "Q9QZS3-1", "name": "Protein numb homolog", "aln": "-----------------------------------------MNKLRQSFR---RKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDAKKAETDKTVVGPSVAPGNTAPSPS--SPTSPTPDGTASSEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNTVPEVE----GEAESISSLCSQITSAFSTPSEDPFSSAPMTKPVTLVAPQSPVLQANGTDSASHVLTAKPANTALAHVAMPVRETNPWAHVPDAANKEIAAIHPGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQVSAAPLQPVLQ-------------PPPPAAIAPPAPPFQGHAFLTSQPVPVGVVPPLQPAFVPTQSYPVANGMPYP-ASNVPVVGITPSQMVANVFGTAGHPQTTHPHQSPSLAKQQTFPQYETSSATTSPFFKPPAQHLNGSAAFNGVDNGGLASGNRHAEVPPGTCPVDPFEAQWAALESKSKQRTNPSPTNPFSSDLQKTFEIEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49757-1", "uniprot_id": "NUMB_HUMAN", "id": "P49757-1", "name": "Protein numb homolog", "aln": "-----------------------------------------MNKLRQSFR---RKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS--SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTP-EDPFSSAPMTKPVTVVAPQSPTFQANGTDSAFHVL-AKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ-------------PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYP-APNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16554-1", "uniprot_id": "NUMB_DROME", "id": "P16554-1", "name": "Protein numb", "aln": "MGNSSSHTHEPLERGFTRGKFGDVKNGKSASFRFSKKSPKKMDRLRRSFRDSFRRRKDRVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEALKVLRQS-----------RRRPVRGLLHVSGDGLRVVDDETKGLIVDQTIEKVSFCAPDRNHERGFSYICRDGTTRRWMCHGFLACKDSGERLSHAVGCAFAVCLERKQRRDKECGVTMTFDTKNSTFTRTGSFRQQT---LTERLAMATVGTNERSVD----------GPGSAMPGPP-----------AATVKPFNPFAIERPHATPNMLERQSSFR-LSTIGSQ-SPFKRQMSLRINDLPSNADRQRAFLTAAAGNPMQ----TPLRSVSPIA-EVSPAKSAG------ADPLSAAAVAADSVS----------------------------------------------------------QLCQELSQGLSLLTQTDALLAAGEDLNFNNNRSINQNIIAAEKQVQHVHS------------YAPPTAQVTP----------RVASTTPTYQTLHSQSPSRSEQSIETSTELPNA------------EQWLGHVVRSTSPAAPKRPTYLANVGRAQTLASGTGAAVGGG------GPDDPFDAEWVAN----------VAAAKQLSPDLPIPSTARSPLARHS---TNPFISPPKAP--AQSFQVQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::**:*:* *:: ***:*:*****:**:.**...***.*:*** *** *****::**:*:* *: ::.*:.:* **.*******::**.*:**************** ::.*************:** *:* **:*************.******:*:****** :**:..::*:* **** :** . : . ** * *. :. .. ** * **. : * **.*** :.::..: ******:***:*:***. :*: * : :: .:..:. ::: : :: . * . . . * : . . : : * . *: .: *: * .* . :. ..... . .. . : . .* :.:.. ::. * . : : ::. .:. . . .* : . : : .: :.* :. : : * : ::*:::*", "identical_positions": 168, "similar_positions": 156, "identity": "23.43%" }, { "cls_id": "homologset.agr.FB:FBgn0002985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K011-1", "uniprot_id": "OSR1_RAT", "id": "B0K011-1", "name": "Protein odd-skipped-related 1", "aln": "--MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLMDARFQLPAFPWFPHVIHPKPEITAGGSGAALKTKPRFDFANLALAATQE---------------------DPTKLGRGEGPGSPAGGLGALLD-VTKLSPEKK---------------------PTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAX0-1", "uniprot_id": "OSR1_HUMAN", "id": "Q8TAX0-1", "name": "Protein odd-skipped-related 1", "aln": "--MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGTVSSLVDARFQLPAFPWFPHVIQPKPEITAGGSVPALKTKPRFDFANLALAATQE---------------------DPAKLGRGEGPGSPAGGLGALLD-VTKLSPEKK---------------------PTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AY34-1", "uniprot_id": "OSR2_RAT", "id": "Q6AY34-1", "name": "Protein odd-skipped-related 2", "aln": "--MGSKALPAPIPLHPSLQLTNYSFLQAVNTFP-AAVDHLQGLYGLSAVQTMHMNHWTLGYPNVHEITRSTITEMAAAQGLVDARFPFPALPFATHLFHPKQGAIAHVLPALHKDRPRFDFANLAVAATQE---------------------DPPKMG---DLSKLSPGLGSPISGLSKLTPDRK---------------------PSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTS---SPTAASSAAKCSG--------------ETVICGGTA---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZD1-1", "uniprot_id": "OSR2_MOUSE", "id": "Q91ZD1-1", "name": "Protein odd-skipped-related 2", "aln": "--MGSKALPAPIPLHPSLQLTNYSFLQAVNTFP-AAVDHLQGLYGLSAVQTMHMNHWTLGYPSVHEITRSTITEMAAAQGLVDARFPFPSLPFATHLFHPKQGAIAHVLPALHKDRPRFDFANLAVAATQE---------------------DPPKMG---DLSKLSPGLGSPISGLSKLNPDRK---------------------PSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHTPRQNF--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q567J8-1", "uniprot_id": "OSR2_DANRE", "id": "Q567J8-1", "name": "Protein odd-skipped-related 2", "aln": "--MGSKTLPAPVPLHPAPQLN-YSLLRTLNAFP-VAVDQL---YGLSALHTVQMNRWTVGFP--------------QLQGLADPRFPG-ALPFPAAAAHLLP----HKHPVHRKDRPRFDFANLAVAATQE---------------------DPPVTG------------------QSRLSPERR---------------------PARGRLPAKSKKEFICRFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHLQTSSLSAAAAAGRCFG-----------------ATATCGATV---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23803-1", "uniprot_id": "ODD_DROME", "id": "P23803-1", "name": "Protein odd-skipped", "aln": "MSSTSASPISNITVDDELNLSREQDFAEEDFIVIKEERETSLSPMLTPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQAPQQYPVYPTASADPVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHHHHHGHPHHPHPHPHHVRPYPAGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQRSFNQRANLKSHLQSHSEQSTKEVVVTTSPATSHSVPNQALSSPQPENLAQHLPVLDLSSSSSSSEKPKRMLGFTIDEIMSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : :.:. :*. . : : : . ::. :: . .* : : : * . :*: . * * . *: . .::.**:*:*::*.*:********************:**** ******************:*****.:***************. * : . ", "identical_positions": 77, "similar_positions": 47, "identity": "19.64%" }, { "cls_id": "homologset.agr.FB:FBgn0002989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EM66-1", "uniprot_id": "F7EM66_RAT", "id": "F7EM66-1", "name": "DNA repair and recombination protein RAD54-like", "aln": "MRRSLAPSQL-----ARRKP----------EDISSDDEDWQPETVTPKKRKSTAETQAQQCFLS---PFRKP------------------------LTQLLNR-------PPCLDSSQHEAFIRSILSKPFKVPIPNYQGPLG-SRALGLKRAGVR--RALHDPLEEGALVLYEPPP----------------------LSVHDQLKLDKEK--------------------------------------------LPVHVVVDPILSKVLRPHQREGVKFLWECVT----------------------------------SRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPECKPEIEKAVVVSPSSLVKNWYNEVEKWLG-GRIQPLAIDG------GSKDEIDRKLEGFMNQRGARVPSPILIISYETFRLHVEVLKKGNVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKSRDAAASEADRQLGEERLRELISIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPEEELHEG--KMSVSSLSSITSLKKLCNHPALI-YDKCVAEEDGFEGTLGIFPPGYNSKAVEPQLSGKMLVLDYILAMTRSRSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKICYIYRLLSMLLAVFFGCLAGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELFTLDEASLSDTHDRLHCRRC-VNNRQVWPPPDGSDCTSDLAQWNHNTDKRGLQDEVLQAAWDASSTAITFVFHQRSHEEQRGLHC----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70270-1", "uniprot_id": "RAD54_MOUSE", "id": "P70270-1", "name": "DNA repair and recombination protein RAD54-like", "aln": "MRRSLAPSQL-----ARRKP----------EDRSSDDEDWQPGTVTPKKRKSSSETQVQECFLS---PFRKP------------------------LTQLLNR-------PPCLDSSQHEAFIRSILSKPFKVPIPNYQGPLG-SRALGLKRAGVR--RALHDPLEEGALVLYEPPP----------------------LSAHDQLKLDKEK--------------------------------------------LPVHVVVDPILSKVLRPHQREGVKFLWECVT----------------------------------SRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPECKPEIEKAVVVSPSSLVKNWYNEVEKWLG-GRIQPLAIDG------GSKDEIDRKLEGFMNQRGARVPSPILIISYETFRLHVGVLKKGNVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKSRDAAASEADRQRGEERLRELIGIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPEEELREG--KMSVSSLSSITSLKKLCNHPALI-YDKCVAEEDGFEGTLGIFPPGYNSKAVEPQLSGKMLVLDYILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRVRRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKICYIYRLLS----------AGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELFTLDEASLSDTHDRLHCRRC-VNNRQVWPPPDGSDCTSDLAQWNHSTDKRGLQDEVLQAAWDASSTAITFVFHQRSHEEQRGLH-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92698-1", "uniprot_id": "RAD54_HUMAN", "id": "Q92698-1", "name": "DNA repair and recombination protein RAD54-like", "aln": "MRRSLAPSQL-----AKRKP----------EGRSCDDEDWQPGLVTPRKRKSSSETQIQECFLS---PFRKP------------------------LSQLTNQ-------PPCLDSSQHEAFIRSILSKPFKVPIPNYQGPLG-SRALGLKRAGVR--RALHDPLEKDALVLYEPPP----------------------LSAHDQLKLDKEK--------------------------------------------LPVHVVVDPILSKVLRPHQREGVKFLWECVT----------------------------------SRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLG-GRIQPLAIDG------GSKDEIDQKLEGFMNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEG--KMSVSSLSSITSLKKLCNHPALI-YDKCVEEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLS----------AGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELFILDEASLSDTHDRLHCRRC-VNSRQIRPPPDGSDCTSDLAGWNHCTDKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQRGLR-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8K0-1", "uniprot_id": "RAD54_DANRE", "id": "F1Q8K0-1", "name": "DNA repair and recombination protein RAD54-like", "aln": "MRRSLAPSQV-----AKRKQ----------GPDSDDEEDWEPDMEPQCKR------DCREKYIS---PYRKP------------------------LTPLTNR-------PFCADGNEHEAFIRKILSKPFKIPIPNYTGVLG-LRALGLRRAGVR--KALHDPFEDGALVLYEPPV----------------------ISAHDLIKADKEK--------------------------------------------LPVHVVVDPVLSKVLRPHQREGVKFLWDCVT----------------------------------GRRIENSYGCIMADEMGLGKTLQCITLIWTLLKQSPDCKPEIDKVIVVSPSSLVRNWYNEVGKWLG-GRVQPVAIDG------GSKDEIDSKLVNFISQQGMRIPTPILIISYETFRLHAEVLHKGKVGLVICDEGHRLKNSDNQTYLALNSMNAQRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKKRFEIPILKGRDADASDKDRAAGEQKLQELISIVNRCLIRRTSDILSKYLPVKIEQVVCCNLTPLQKELYKLFLKQAKPVESLQTG--KISVSSLSSITSLKKLCNHPALI-YEKCLTGEEGFDGALDLFPQNYSTKAVEPQLSGKMLVLDYILAMTRTTTSDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKIVERFNNPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLS----------TGTIEEKILQRQAHKKALSSCVVDEEQDVERHFSLGELRELFSLNEKTLSDTHDRFRCRRC-VNGRQVRPPPDDSDCTCDLSNWHHCADKRGLRDPVLQASWDA---AVSFVFHQRSHEDQRGVV-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76460-1", "uniprot_id": "RAD54_DROME", "id": "O76460-1", "name": "DNA repair and recombination protein RAD54-like", "aln": "MRRSLAPSQR-----GPLRP----------ESRHSFTPPLLKKNKRSCQQELEREQELDRRRLG---ALRDASN----------------------TSELPLP-------IRFTANSEYELAIAKVLARKFKVPMDNYVPDYGGKRVLGVRRCISR--RPLHDPMACNALVLFHPPA----------------------YTEHERMGMDPTK--------------------------------------------VLVHVVVDPLLSNILRPHQREGVRFMYECVE----------------------------------GKRG-NFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNWEKEFTKWLH-GRLLCLPMEG------GTKENTIRALEQFS-MTSARLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKICSHPDLI-YEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVA----------SGSIEEKILQRQTHKKSLSSTIIDNNESAEKHFTRDDLKDLFTFDANILSDTHDKLKCKRC-VQNIQMKPPPEDTDCTSHLSQWYHCSNNRGLPDNILAQAWMD-CKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPESRKRSSTPASDDSADEDFRGF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32863-1", "uniprot_id": "RAD54_YEAST", "id": "P32863-1", "name": "DNA repair and recombination protein RAD54", "aln": "MARRRLPDRPPNGIGAGERPRLVPRPINVQDSVNRLTKPFRVPYKNTHIPPAAGRIATGSDNIVGGRSLRKRSATVCYSGLDINADEAEYNSQDISFSQLTKRRKDALSAQRLAKDPTRLSHIQYTLRRSFTVPIKGYVQRHSLPLTLGMKKKITPEPRPLHDPTDEFAIVLYDPSVDGEMIVHDTSMDNKEEESKKMIKSTQEKDNINKEKNSQEERPTQRIGRHPALMTNGVRNKPLRELLGDSENSAENKKKFASVPVVIDPKLAKILRPHQVEGVRFLYRCVTGLVMKDYLEAEAFNTSSEDPLKSDEKALTESQKTEQNNRGAYGCIMADEMGLGKTLQCIALMWTLLRQGPQGKRLIDKCIIVCPSSLVNNWANELIKWLGPNTLTPLAVDGKKSSMGGGNTTVSQAIHAWAQAQGRNIVKPVLIISYETLRRNVDQLKNCNVGLMLADEGHRLKNGDSLTFTALDSISCPRRVILSGTPIQNDLSEYFALLSFSNPGLLGSRAEFRKNFENPILRGRDADATDKEITKGEAQLQKLSTIVSKFIIRRTNDILAKYLPCKYEHVIFVNLKPLQNELYNKLIKSREVKKVVKGVG---GSQPLRAIGILKKLCNHPNLLNFEDEFDDEDDLELPDDYNMPGSKARDVQTKYSAKFSILERFLHKIKTESDDKIVLISNYTQTLDLIEKMCRYKHYSAVRLDGTMSINKRQKLVDRFNDPEGQEFIFLLSSKAGGCGINLIGANRLILMDPDWNPAADQQALARVWRDGQKKDCFIYRFIS----------TGTIEEKIFQRQSMKMSLSSCVVDAKEDVERLFSSDNLRQLFQKNENTICETHETYHCKRCNAQGKQLKRAP--AMLYGDATTWNHLNHDALEKTNDHLLKNEHHYNDISFAFQYISH------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *.: . : : . *. : * . * * : *.:*: .* . .**::: :.**** *:**:.*. : :: : * * **:** *:::***** ***:*:: ** :. . ****************::*:****:*.*: * *:* ::*.*****.** :*. *** . : :.::* * : : : . .: .*:*:*****:* . * : .**:::.********.:. *: ** .:. ***::********* **::*: * *. :**: *::.** .**:.::: ::: : . : ::* :*.: :****.:**:**** * * *: .*..:* ***. :::. : . : . .* * ***:*.** *: ::. *..: . . . ..: ::.: *.*: :*: :* :: .**:**:*********:*::.* ::* *********:** *:*:***.*.. .*:*:*********:********.::******* *:**:********** *:***::: :*:*****:***: * :*** ::* ::..*: *: .:*::** : :.:**: :*:** .:. *: .* : . : * * .. ::*.*: *: ", "identical_positions": 265, "similar_positions": 222, "identity": "27.75%" }, { "cls_id": "homologset.agr.FB:FBgn0003002", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZJD4-1", "uniprot_id": "A0A8I5ZJD4_RAT", "id": "A0A8I5ZJD4-1", "name": "Zinc finger protein ZIC 5", "aln": "---------------------------------------------------------------------------------MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLAGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQTSGHGPSPPTQALPELPQATAPAARSPASGTHPGARTHHDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPPALSGYTATNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDG-----GGSALFPALHD---SPGAPGG------HPLNGQMRLGLAAAAAAAA-ELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAP----HPHHPHLPGAAGAFLRYMRQP-------IKRELICKWLDPEELAG-----------PPAPADSGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCK-------SPPPSPGALGYS-SVGTPVGDTLSPVLDPTRSRSSTLSPQVTNLNEWYVCQA------------------GGAPSHLHTPSSN--------------------GTTSESEDEEMYGNPEVMRTIH----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQ40-1", "uniprot_id": "ZIC5_MOUSE", "id": "Q7TQ40-1", "name": "Zinc finger protein ZIC 5", "aln": "---------------------------------------------------------------------------------MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLVGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQASGQGPCPPSQGLPGLFQVPAPAARSVASGTHPGARTHPDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPP-ALSGYTATNSGGGSSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDG-----GGSALFPALHD---SPGAPGG------HPLNGQMRLGLAAAAAAAA-ELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAP----HPHHPHLPGAAGAFLRYMRQP-------IKRELICKWLDPEELAG-----------PPASADSGVKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCK-------SPPPSPGALGYS-SVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQA------------------SGAPSHLHTPSSN--------------------GTTSESEDEEMYGNPEVMRTIH----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T25-1", "uniprot_id": "ZIC5_HUMAN", "id": "Q96T25-1", "name": "Zinc finger protein ZIC 5", "aln": "----------------------------------------------------------------------------------MEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPP-ALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGS----GGPALFPALHD---TPGAPGGHP----HPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAG-PGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQP-------IKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCK-------SPPPSPGPLGYS-SVGTPVGAPLSPVLDPARSHSSTLSPQVTNLNEWYVCQA------------------SGAPSHLHTPSSN--------------------GTTSETEDEEIYGNPEVVRTIH----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NAP2-1", "uniprot_id": "A0A8M1NAP2_DANRE", "id": "A0A8M1NAP2-1", "name": "", "aln": "------------------------------------------------------------------------MSVDALGSPVMDPAFSKRN-TTLRLVDLAGAHHHHHHHHHTPQSVTGFPGFSSHPHSMAHSHPGEMTAEPRLGPSPFGPEHMGHSAALKISP----------------------THHYPHHHHHHNHHIAGHSEVVSSQTGAFGPVQAATVP------------YSMSHTAQALSAG----RDFLIRRELTAQA-------MPVLTDQTSGSAS---------HHGMFVSTTGSYPGHYGHHPDPGNHTLFPGLHHDQPSTGAPGG------QALNGQIRLGIPA-------EMYVRSDHLSQVASSRADP-----FAASPLHGYGGLNLNMNLSA---------------------------------HHHH-----GAGAFFRYMRQP-------IKQELICKWLEPEHSAK--------------------KLCSKTYSTMHELVTHVTVEHVGGPEQANHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRRFANSSDRKKHSHVHTSDKPYNCKVRGCDKSYTHPSSLRKHMKVHCK-------SPPPSSGYESSTPSLVSPSSDLGREPAPSALSEPLSSSSQPANLSEWYVCHS------------------SGASGPQTPPSGS--------------------STPGHTEG-PTYGNPERRDAF-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6ATI6-1", "uniprot_id": "A0A8I6ATI6_RAT", "id": "A0A8I6ATI6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MAQAQKMKYKT-----------SLVMRKRLRLYRNTLKESS-SSCGHHGPQLAAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------NPSVFPGLHEQ--PPQASHS------RPLNGLLRLGIPG-------DMYARSEPFAPGPMARGDT----LATATALHGYGGMNLTMNLTAP----------------------------------------HGPGAFFRYMRQP-------IKQELICKWLGDDSPIS-------------------PRPCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYMCKVRGCDKCYTHPSSLRKHMKVHGR-------SPPPSSGYDSAITSALTSTS--LESGREPSVACSAAVVVRGTDVSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61467-1", "uniprot_id": "ZIC4_MOUSE", "id": "Q61467-1", "name": "Zinc finger protein ZIC 4", "aln": "-----------------------------------------------------------------------------------------------------MRLGRVCPRGP-----------GKVRSPRHRFSCTLFVSTTGSSCGHHGPQLAASS-----------------------------------------------------------------------------------------------------------------------------------------------------------------NPSVLPGLHEQ--PPQASHS------RPLNGLLRLGIPG-------DMYARSEPFAPGPMARSDT----LATATALHGYGGMNLTMNLTAP----------------------------------------HGPGAFFRYMRQP-------IKQELICKWLGDDSPMS-------------------PRPCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYMCKVRGCDKCYTHPSSLRKHMKVHGR-------SPPPSSGYDSAITSALASPS--LESGREPSVACSAAVVVRGTDVSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9L1-1", "uniprot_id": "ZIC4_HUMAN", "id": "Q8N9L1-1", "name": "Zinc finger protein ZIC 4", "aln": "-----------------------------------------------------------------------------------------------------------MRYKT-----------SLVMRKRLRLYRNTLKESS-SSSGHHGPQLTAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------SPSVFPGLHEE--PPQASPS------RPLNGLLRLGLPG-------DMYARPEPFPPGPAARSDA----LAAAAALHGYGGMNLTVNLAAP----------------------------------------HGPGAFFRYMRQP-------IKQELICKWLAADGTAT-------------------PSLCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGR-------SPPPSSGYDSATPSALVSPS--SDCGHKSQVASSAAVAARTADLSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O95409-1", "uniprot_id": "ZIC2_HUMAN", "id": "O95409-1", "name": "Zinc finger protein ZIC 2", "aln": "-----------------------------------------------------------------------------------MLLDAGPQFPAIGVGSFARHHHHSAAAAAA--------AAAEMQDRELSLAAA-QNGFVDSAAAHMGAFKLNPG-AHELSP----------------------GQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYS-------------------GPP---FNSTRDFLFRSR--GFGDSAPGG----------------------GQHGLFGPGAGGLH--HAHSD-AQGHLLFPGLP-EQHGPHGSQN-------VLNGQMRLGLPG-------EVFGRSEQYRQVASPRTDP----YSAAQLHNQYGPMNMNMGMNMAA-----------------------------AAAHHHHHHHHHPGAFFRYMRQQC------IKQELICKWIDPEQLSN------------------PKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHR------------------GGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62520-1", "uniprot_id": "ZIC2_MOUSE", "id": "Q62520-1", "name": "Zinc finger protein ZIC 2", "aln": "-----------------------------------------------------------------------------------MLLDAGPQFPAIGVGSFARHHHHSAAAAAA--------AAAEMQDRELSLAAA-QNGFVDSAAAHMGAFKLNPG-AHELSP----------------------GQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYS-------------------GPP---FNSTRDFLFRSR--GFGDSAPGG----------------------GQHGLFGPGAGGLH--HAHSD-AQGHLLFPGLPPEQHGPHASQN-------VLNGQMRLGLPG-------EVFGRSEQYRQVASPRTDP----YSAAQLHNQYGPMNMNMGMNMAA-----------------------------AAAHHHHHHHH-PGAFFRYMRQQC------IKQELICKWIDPEQLSN------------------PKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHR------------------GAGSGSSGSGGGS--AAGSGGGGGGAGGGGGGSSGGGSGTTGGHSGLSSNFNEWYV---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M7V7-1", "uniprot_id": "A0ABK0M7V7_RAT", "id": "A0ABK0M7V7-1", "name": "", "aln": "-----------------------------------------------------------------------------------MLLDAGPQFPAIGVGSFARHHHHSAAAAAA--------AAAEMQDRELSLAAA-QNGFVDSAAAHMGAFKLNPG-AHELSP----------------------GQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYS-------------------GPP---FNSTRDFLFRSR--GFGDSAPGG----------------------GQHGLFGPGAGGLH--HAHSD-AQGHLLFPGLP-EQHGPHASQN-------VLNGQMRLGLPG-------EVFGRSEQYRQVASPRTDP----YSAAQLHNQYGPMNMNMGMNMAA-----------------------------AAAHHHHHHHH-PGAFFRYMRQQC------IKQELICKWIDPEQLSN------------------PKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHR------------------GAGSGSSGSGGGS--AAGSAGQPE-AIAASPPTSMNGTCEGPGLSPIPCSLIHRRPPKNPPRAP-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46684-1", "uniprot_id": "ZIC1_MOUSE", "id": "P46684-1", "name": "Zinc finger protein ZIC 1", "aln": "-----------------------------------------------------------------------------------MLLDAGPQYPAIGVTTFGASRHHSAG---------------DVAERDVGLG-------INPFADGMGAFKLNPS-SHELAS----------------------AGQTAFTSQAPG------YAAAAALGHHHHPGHVGSYS-------------------SAA---FNSTRDFLFRNR--GFGDAAAAAS---------------------AQHSLFAASAGGFGGPHGHTD-AAGHLLFSGLH-EQAAGHASPN-------VVNGQMRLGFSG-------DMYPRPEQYGQVTSPRSEH----YAAPQLHG-YGPMNVNM------------------------------------AAHHG------AGAFFRYMRQP-------IKQELICKWIEPEQLAN------------------PKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPTTDNPTTSSMSPSS--------------SAVHH------------------TAG----------------------------------------HSALSSNFNEWYV---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LH97-1", "uniprot_id": "A0ABK0LH97_RAT", "id": "A0ABK0LH97-1", "name": "", "aln": "MGLQSTCWRQLIIRMWPHQNGHSVPGDSRSQGKLQLRVAPRGSPGSAQPPPSLSDYGPSGISFACTLAHFSRIFCVQNAPPMTMLLDGGPQFPGLGVGSFGAPRHHEMP---------------NREPAAMGLNPFGDSTHAAAAAAAAAAFKLSPATAHDLSS----------------------GQSSAFTPQGSG-YANALG-HHHHHHHHHHASQVPTYG-------------------GAASAAFNSTRDFLFRQRGSGLSEAASGG----------------------GQHGLFAGSASSLHAPAGIPE-PPSYLLFPGLH-EQGAGHPSPTG-----HVDNNQVHLGLRG-------ELFGRADPYRPVASPRTDP----YAASAQFPNYSPMNMNMGVN--------------------------------VAAHHG------PGAFFRYMRQP-------IKQELSCKWIEEAQLSR------------------PKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKV--CDKSYTHPSSLRKHMKVHES--QGSDSSPAASSGYESSTPPAIASANSKDTTKT-------------------PSAVQT------------------STS---------------------------------------HNPGLPPNFNEWYV---------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62521-1", "uniprot_id": "ZIC3_MOUSE", "id": "Q62521-1", "name": "Zinc finger protein ZIC 3", "aln": "---------------------------------------------------------------------------------MTMLLDGGPQFPGLGVGSFGAPRHHEMP---------------NREPAGMGLNPFGDSTHAAAAAAAAAAFKLSPATAHDLSS----------------------GQSSAFTPQGSG-YANALG-HHHHHHHHHHASQVPTYG-------------------GAASAAFNSTRDFLFRQRGSGLSEAASGG----------------------GQHGLFAGSASSLHAPAGIPE-PPSYLLFPGLH-EQGAGHPSPTG-----HVDNNQVHLGLRG-------ELFGRADPYRPVASPRTDP----YAASAQFPNYSPMNMNMGVN--------------------------------VAAHHG------PGAFFRYMRQP-------IKQELSCKWIEEAQLSR------------------PKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKV--CDKSYTHPSSLRKHMKVHES--QGSDSSPAASSGYESSTPPAIASANSKDTTKT-------------------PSAVQT------------------STS---------------------------------------HNPGLPPNFNEWYV---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60481-1", "uniprot_id": "ZIC3_HUMAN", "id": "O60481-1", "name": "Zinc finger protein ZIC 3", "aln": "---------------------------------------------------------------------------------MTMLLDGGPQFPGLGVGSFGAPRHHEMP---------------NREPAGMGLNPFGDSTHAAAAAAAAAAFKLSPAAAHDLSS----------------------GQSSAFTPQGSG-YANALGHHHHHHHHHHHTSQVPSYG-------------------GAASAAFNSTREFLFRQRSSGLSEAASGG----------------------GQHGLFAGSASSLHAPAGIPE-PPSYLLFPGLH-EQGAGHPSPTG-----HVDNNQVHLGLRG-------ELFGRADPYRPVASPRTDP----YAAGAQFPNYSPMNMNMGVN--------------------------------VAAHHG------PGAFFRYMRQP-------IKQELSCKWIDEAQLSR------------------PKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKV--CDKSYTHPSSLRKHMKVHES--QGSDSSPAASSGYESSTPPAIASANSKDTTKT-------------------PSAVQT------------------STS---------------------------------------HNPGLPPNFNEWYV---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39768-1", "uniprot_id": "OPA_DROME", "id": "P39768-1", "name": "Pair-rule protein odd-paired", "aln": "---------------------------------------------------------------------------------MMMNAFIEPAQHHLASYGLRMSPNTTASNSN----------AQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAAATAAAYQN--------------------------------------------------SGYGHFNSYA----------------------------SRDFLLGRR----------------------------------------EAEYGVAGSAGQASAAADSMLFSGFPAQAAELGSGFGQHPFHSHHHHHQMRMGMAD--------AYAAGHPYNHHGNFPTAA-----VHHPVVHHPSHHAMSAMHPAG------------------------------------------AGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLVP--------------PGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTASSSASHLLQHQQHQHQQQQQQQQHQQQAQQQQQLTAHPSDPKSSPALQLMAASASAYLPPPLGPPPSHHHHPHHHQAAPSPGAAAASASMLHHNHHLLYHPAAQHHPPSDWYHTTAPSGSAEAMNPLNHFGHHHHHHHLMHPGAATAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::..: : :::*: : . . :. .***:****: :*:*: * *: *.:.: :***:*.*:::******* .* *:* *.*:*:.*******:************.**.*****:********************:**.:**:*:********** ********* *:: ***.************:* * * . . ", "identical_positions": 120, "similar_positions": 54, "identity": "13.53%" }, { "cls_id": "homologset.agr.FB:FBgn0003008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59780-1", "uniprot_id": "AP3S2_HUMAN", "id": "P59780-1", "name": "AP-3 complex subunit sigma-2", "aln": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRD-DNICNFLEG-----------GSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDK-------------VHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BSZ2-1", "uniprot_id": "AP3S2_MOUSE", "id": "Q8BSZ2-1", "name": "AP-3 complex subunit sigma-2", "aln": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRD-DNICNFLEG-----------GSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDK-------------VHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K302-1", "uniprot_id": "A0A0G2K302_RAT", "id": "A0A0G2K302-1", "name": "", "aln": "MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRD-DNICNFLEG-----------GSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVQSAEVTIFISLTVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCR2-1", "uniprot_id": "AP3S1_MOUSE", "id": "Q9DCR2-1", "name": "AP-3 complex subunit sigma-1", "aln": "MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRD-ENVCNFLEG-----------GLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDK-------------VHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92572-1", "uniprot_id": "AP3S1_HUMAN", "id": "Q92572-1", "name": "AP-3 complex subunit sigma-1", "aln": "MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRD-ENVCNFLEG-----------GLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDK-------------VHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKR4-1", "uniprot_id": "A0A8I6AKR4_RAT", "id": "A0A8I6AKR4-1", "name": "", "aln": "--GPFPPFPDFSILKLLSFIFR-IEDTQQQIIRETFHLVSKRD-ENVCNFLEG-----------GLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDK-------------VHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W1E8-1", "uniprot_id": "Q9W1E8_DROME", "id": "Q9W1E8-1", "name": "", "aln": "MIKAILVFNNHGKPRLSKFYQYFDESLQQQIIKETFQLVSKRD-DNVCNFLEG-----------GSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHADA-------------VHHILSELVMGGMVLQTNMNDIMARIEEQNKIVKQEAGISAAPARAVSAVKSMNIPQQIKDIKLPDLPQAIKDFKF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47064-1", "uniprot_id": "AP3S_YEAST", "id": "P47064-1", "name": "AP-3 complex subunit sigma", "aln": "MIHAVLIFNKKCQPRLVKFYTPVDLPKQKLLLEQVYELISQRNSDFQSSFLVTPPSLLLSNENNNDEVNNEDIQIIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNELDLIFNWQT-------------LESVLEEIVQGGMVIETNVNRIVASVDELNKAAES-------TDSKIGRLTSTGFGSALQAFAQGGFAQWATGQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * . :* * *: ::.:.:.*: :*: : ..** . :...* ::**::******.* **..****.******.***:**:** :* ******: : :. :* *:* ****::**:* *:: :: *: :. . :. :.. .: . : : .: . ", "identical_positions": 56, "similar_positions": 65, "identity": "25.69%" }, { "cls_id": "homologset.agr.FB:FBgn0003011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07727-1", "uniprot_id": "GLRA1_RAT", "id": "P07727-1", "name": "Glycine receptor subunit alpha-1", "aln": "----------------------------------------------------------------------------------------MYSFNTLRFYLWETIVFFSLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQG-AVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRKRRHHKSPM--------------------------------LNLFQDDEGGEGR-FNFS------AYGMGPACLQAKDGISVKGANNNNTTNPAPAPSKSPEEMR------KLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64018-1", "uniprot_id": "GLRA1_MOUSE", "id": "Q64018-1", "name": "Glycine receptor subunit alpha-1", "aln": "----------------------------------------------------------------------------------------MYSFNTLRFYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQG-AVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRKRRHHKSPM--------------------------------LNLFQDDEGGEGR-FNFS------AYGMGPACLQAKDGISVKGANNNNTTNPPPAPSKSPEEMR------KLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23415-1", "uniprot_id": "GLRA1_HUMAN", "id": "P23415-1", "name": "Glycine receptor subunit alpha-1", "aln": "----------------------------------------------------------------------------------------MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQG-AVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRKRRHHKSPM--------------------------------LNLFQEDEAGEGR-FNFS------AYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMR------KLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O93430-1", "uniprot_id": "GLRA1_DANRE", "id": "O93430-1", "name": "Glycine receptor subunit alphaZ1", "aln": "----------------------------------------------------------------------------------------MFALG---IYLWETIVFFSLAASQQA-AARKAASPMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKG-AVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIA--RQHKELLRFQRRRRHLK----------------------------------------EDEAGDGR-FSFA------AYGMGPACLQAKDGMAIKGNNNNAPTSTNP-PEKTVEEMR------KLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24524-1", "uniprot_id": "GLRA3_RAT", "id": "P24524-1", "name": "Glycine receptor subunit alpha-3", "aln": "-----------------------------------------------------------------------------------MAHVRHFRTLLSGFYFWEAALLLSLVATKETNSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEA-PVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRKRKNKTEAF--------------------------ALEKFYRFSDTDDEVRESR-LSFT------AYGMG-PCLQAKDGVVPKG-----PNHAVQVMPKSADEMR------KVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHHQQD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XP5-1", "uniprot_id": "GLRA3_MOUSE", "id": "Q91XP5-1", "name": "Glycine receptor subunit alpha-3", "aln": "-----------------------------------------------------------------------------------MAHVRHFRTLVSGFYFWEAALLLSLVATKETNSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEA-PVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRKRKNKTEAF--------------------------ALEKFYRFSDTDDEVRESR-FSFT------AYGMG-PCLQAKDGVVPKG-----PNHAVQVMPKSPDEMR------KVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75311-1", "uniprot_id": "GLRA3_HUMAN", "id": "O75311-1", "name": "Glycine receptor subunit alpha-3", "aln": "-----------------------------------------------------------------------------------MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEA-PVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRKRKNKTEAF--------------------------ALEKFYRFSDMDDEVRESR-FSFT------AYGMG-PCLQAKDGMTPKG-----PNHPVQVMPKSPDEMR------KVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q7Y2-1", "uniprot_id": "A0A8M9Q7Y2_DANRE", "id": "A0A8M9Q7Y2-1", "name": "", "aln": "-----------------------------------------------------------------------------------MTRKRLRSVAAWGFIAWEIGILLSLVASKEPESPRRRAAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKG-PVQVADGLTLPQFILKDESDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS--RQHKELLRFRRRRKKSGKTFDQTFDEELAESLRRINGSRSAEPVYGSMGQLDQTNDMEEEVRESR-LSFTP-----NAGKD-GAVPKTANNAATT-----PSEPAVAPGKSHEEMR------KLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRHEDVHKP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22771-1", "uniprot_id": "GLRA2_RAT", "id": "P22771-1", "name": "Glycine receptor subunit alpha-2", "aln": "----------------------------------------------------------------------------------MNRQLVNILTALFAFFLGTNHFREAFCKDHDSRSGKHPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFEYTMNDLIFEWLSDG-PVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVS--RQHKEFLRLRRRQKRQNK--------------------------------------EEDVTRESR-FNFS------GYGMG-HCLQVKDGTAVKAT----PANPLPQPPKDADAIK------KKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNC8-1", "uniprot_id": "GLRA2_MOUSE", "id": "Q7TNC8-1", "name": "Glycine receptor subunit alpha-2", "aln": "----------------------------------------------------------------------------------MYRQLVNILTALFAFFLGTNHFREAFCKDHDSRSGKHPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDG-PVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVS--RQHKEFLRLRRRQKRQNK--------------------------------------EEDVTRESR-FNFS------GYGMG-HCLQMKDGTAVKAT----PANPLPQPPKDADAIK------KKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23416-1", "uniprot_id": "GLRA2_HUMAN", "id": "P23416-1", "name": "Glycine receptor subunit alpha-2", "aln": "----------------------------------------------------------------------------------MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDG-PVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVS--RQHKEFLRLRRRQKRQNK--------------------------------------EEDVTRESR-FNFS------GYGMG-HCLQVKDGTAVKAT----PANPLPQPPKDGDAIK------KKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61603-1", "uniprot_id": "GLRA4_MOUSE", "id": "Q61603-1", "name": "Glycine receptor subunit alpha-4", "aln": "-----------------------------------------------------------------------------------MTTLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVS--RQHKEFMRLRRRQRRQR--------------------------------------MEEDIIRESR-FYFR------GYGLG-HCLQARDGGPMEGSS-IYSPQPPTPLLKEGETMR------KLYVDRAKRIDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JH78-1", "uniprot_id": "A0AC58JH78_DANRE", "id": "A0AC58JH78-1", "name": "", "aln": "MWPERERKSRRPPLHTHTHTHTHTHTRTRIVVSQPVSGCCAQSDGSGGETRVHQNGRPAPQKHICSLKFSHGTPEKQLLNSERMFSVIWRILLELLLVCWMFEGVIRCVFSKELKSPSVRTKPMSPSDFLDKLMGKTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEG-PVQVADDLMLPQFVLKEEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVS--RQYKEFFRLRRKLRQEQRNRAASGQAGAAETKNKSNNVTGGTPSRNAQRQCSACAREEQLASQNQDLYFP--------GFGIDTSLSGDGPLSEAA----AMFAGLPPGHALFDIR------RRFVEQAKRIDTISRAVFPLSFLVFNVFYWVTYKVLRNEDIHLALRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDU9-1", "uniprot_id": "Q9VDU9_DROME", "id": "Q9VDU9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------MVFQIIILVICTICMKHYAKGEFQQSLAITDILPEDIKR---YDKMRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTT-PLVVDENIELPQVALIRN-ETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFYEYL----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .:. :::* : : : ** *: :* *. * :: : .:.*: *.:* * ::*: * *:* ** * :: *: . *..:*:** ** * *.. *: :* *: : : :: .:** :::** *:* *:: :* * * * :*:**: :* :**:*:* .: * :.: ***. * : : **: *.**:***:*. * *:*:: **::: ***: : **:**:****: :****** **:*::**::** : *::*** ***:**:* :*:** :*** **:**. :*:: : : : :: : : . . . . . . : : :.:* ** ** ** * :* :** : ", "identical_positions": 124, "similar_positions": 124, "identity": "20.77%" }, { "cls_id": "homologset.agr.FB:FBgn0003016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LC42-1", "uniprot_id": "A0ABK0LC42_RAT", "id": "A0ABK0LC42-1", "name": "", "aln": "---------------------------MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQACSQEPHSPPS---------AEAPYCDLPRCPPALQDPLHTTTCVGQSVDNLGLGLDQEPQRIGSPTTALPAD-----PRNRHRDPEAIPYLEGPAYS------TDEHKDEDPNSNTSSSQDSNTPHDTSNSSSVDWDTVERPG-VVPNRNRLTMMIPRRPQEGLRTDSAQKV----TRSPARGDTAGQRKENSGSGGQSAGQHWVKLRSESGYFSLERQRSGQTQASSGTPPSGPR-TTTQASSAQRDVSQAAS----AQEAPQTSSLPRNTQRDTQRS----------------------------------------------TPRTSSPSRVSQRDTPRIMSTQ--------------------------------------RKNTPLSSPLRPTPETLKTSAPE--------------DGPHVTSP----------LCAQ--------DSSLNRTTQ--------------------------------------------------------------------------------------------------------------------------------------------------RDSSRTSCAQRNNPRTSSPNRTTQRDNPRTSCAQRNNPRTSSPNRTTQQDNPRTSCAQRNNPRTSSPSRTTQHDNPRTSCAQRDNPRTSSPNRTTQQDNP------RMSCAQRNNPRTSSPNRTTQRDNLRTSCAQRNNPRTSSPNRTIHQDNPRTSCVSQNTPRTS----------------------------------------------STQVDKTTASCSRWEHLRSACTQRD----------NPRTLS-QGCTQKDNPGPSSPHRATQGSSSRNPSPHRTNKDIPWASFPLRPTQSD-SSRTSSPSRTKQNQVPWASISLRPTQGDKPQTSAPSKLAHNDPPQQ-YSPS----LATSSSSSHNPGHPSASRTSSPLHPAPRGAPQTSLEPSQPPCAVCIGHRDAPRASSPPRYFQYDPFPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFP-------FLPDTSDAEN--ESPQHDPPQFPPPVCIGYRDAPRASSPPRQFPEPS-FFQDLPRASTESLVPSTDSMHEPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSVDS-LHGSPLLLPQVCIGHRDAPRASSPPRHPPSDVGILAPSPPPGSSG-SRGSAPPGETRHNLEREEYTMLADLPPPRRLAQRVPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQRPSQGQSQ----------LRRQSSPAPSRQVTKPSAKQAEPTRQSRTGPPHPKSPEKHSEGDRQLQRIAPPARTSARPPERKAQIERHLESGYTGLRQPLGGWQSREGLSGPQSPNRHPEKNWGSQEEGLSLGGWPELGGPSL------EGIWRGPPQEHRERWGQSEAWEEPPSNGIQGGPPRGQGSLQELPRPHQPPPSPENSWAGPAECFCARQPEAGTAMGWRAEGTSPHQYSAERPPDLDWRDLLGLLRAPEDGAWTRLPRLDWEGLLELLQARLPQKDPTRHSRDPAKAPGPEPGSSDTEDTLKTESQTQPEGWAKATLANGHRPGQQSESPAQLPSPACTSTQWPTTKVTSGPETSPPVALEQIDHLESHS------PPDLG--PEEPEASEPSRGEDSLADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPALFNPYLLSLGVLRWQRPDLLNFKKGWMSILDEPGE---------------WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSECNKENTLHGYGTQKSSLKIGEQRTG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEVIGRGGPRKVDGSRQSLDYVELSPLTPSSPQRVRTLSRSTPERPSKQEDLERDLAQRSEERRKWFESTDSRTPETPSGDGSRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPLRENKRVPLTALLNQGHSERRGPTSDSHEALEKEVQSLRAQLEAWRLRG--------------EAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPD--------SLRKQHQLDMEALKQELQVLSERYSQKCLEIGALTRQAEEREHTLRCCQQEGQELLRHNQELHSHLSEEIDRLRSFIASQG--TGNSCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KW3-3", "uniprot_id": "TARA_MOUSE", "id": "Q99KW3-3", "name": "TRIO and F-actin-binding protein", "aln": "---------------------------MSMEQDTRALLPTQGTAWATASAPVARLQGPQGDSHQACSQEPHSPSS---------AEAPYCDLPRCPPALQNPLRTTTCVGQSVHSLGLGLGQEPQRVWSPTTALPAEGPAAAPKNRHQDSEGIPYLEGLARSSCTDDNDNKDEDEDPNSNTSSSQDSNTPHDTSNSSSVDWDTTERPG-VVPSRNRLTEMIPRRPQEGLRADSARKA----TRSPARGDTAGQRKENSGSGGQSAGQHWAKLRSESGYFSLERQRSGQTQASSGTPPSGPR-GTTQASSAQRDVFQAAP----AQEAPQTSSLPRNTQRDTQRS----------------------------------------------TPRTSSPSRVSQRDTPRVMSTQ--------------------------------------RKNTPLSSPLRATPETLKISAPE--------------DGTHVTPS----------PCVQ--------DSSLNRTSQ--------------------------------------------------------------------------------------------------------------------------------------------------RDSSRTPCIQWDNPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPCAQRDNPRAASPNRSTQRDSP------RTPCAQRDNPRASSPNRTAQRDNPRTPCAQR--------------DNPRTSCTSQNTPRTP----------------------------------------------STQADKTTASCSKWEHLRSACTQRD----------NPRTFS-QGCTQKDNPGPPSPRRATQGSNSRNPSPHRTNKDIPWASFPLRPTQSD-SPRTSSPSRTKQNQVPWASISLRPTQGDKPQTSAPTRLAHNDPPQQ-YSPS----LATTSSSSHNPGHSSASRTSSPLHAAPRGAPQTSLESSQPPCTVCIGHRDAPRASSPPRYFQYDPFPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFP-------FLPDTSDADN--ESPQHDPPQFPPPVCIGYRDAPRASSPPRQFPEPS-FFQDLPRASTESLVPSTDSMHEPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSIDS-LHGCPLLPPQVCIGHRDAPRASSPPRHPPSDIGLLAPSPPPGSSG-SRGSAPPGETRHNLEREEYTMLADLPPPRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPSQAQSQ----------LRRQSSPAPSRQVTKPSAKQAEPTRQSRTGPPHPKSPDKRPEGDRQLQRTSPPARTPARPPERKAQIERHLESGHTGPRQSLGGWQSQERLSGPQSPNRHPEKSWGSQKEGPSLGGWPELEGPSL------EGIWRGPPQEHREQWGHSEAWEEPPSNGIQGAPPRGQGRLQELSRPHQPTPSSENSWAGPAECSCALQPEASTAVGWRAEGTSPHQRSAERPPDLDWRDLLGLLRAPEDGAWTRLPRLDWEGLLELLQARLPQKDPARHWHDPAKASGPEQGSSGTEDTLKTEPQTQPEGRAKATLANGHRPGQQSESPAQLPSPACTSTQWPTTKVTSGPETSPLAALEQIDHLESHS------PPDLEFQPEEPEASEPSRGEDSRAVQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPALFNPYLLSLGVLRWQRPDLLNFKKGWMSILDEPGE---------------WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDCNKENTLHGYGTQKSSLKIGEQRTG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEVIGRGGPRKADGPRPSLDYVELSPLAPSSPQRMRTLSRSTPERPTKQEDLERDLAQRSEERRKWFESTDGRTPETPSGDGSRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPLRENKRVPLTALLNQAHNDRRGPTSDSHEALEKEVQSLRAQLEAWRLRG--------------EAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPE--------SLRKQHQLDMEALKQELQVLSERYSQKCLEIGALTRQAEEREHTLRRCQQEGQELLRHNQELHSHLSEEIDRLRSFIASQG--TGNSCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2D6-1", "uniprot_id": "TARA_HUMAN", "id": "Q9H2D6-1", "name": "TRIO and F-actin-binding protein", "aln": "-----------------------------MEEVPGDALCEHFEANILTQNRCQNCFHP-EEAHGARYQELRSPSG---------AEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPG--PKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTS------LCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESG-LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAAS----TREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENP------RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSD-GPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFP-------FLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDS-LHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQL---------LRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELP----------RELGK-RSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPS--PSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPAR-TPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQG--------------EAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPD--------GLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQG--MGNGCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKESMRNSLAE----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERE6-1", "uniprot_id": "MPRIP_RAT", "id": "Q9ERE6-1", "name": "Myosin phosphatase Rho-interacting protein", "aln": "------------------------------MSAAKENPCRKFQANIFNKSKCQNCFKP-RESHLLNDEDLTQAKP---------IYGGWLLLAPDGTDFDNPVHRS--------------------------------------RKWQRRFFILYEHGLLRY------------------ALDEMPTTLPQGTIN------------------MNQCTDVVDGEARTGQKFSLCILTP--------------DKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSSGSSSSSSSSSIPSAEKVPTTKSTLWQEEMRA------------------------------------------------KDQP----DGTSLSPVQS----------------------------------------------PS--QSQPPAACTP----------------------------------------------RETGLDSKED-----------------------------------------------------------------------------------------------------------------------------------------------ENILSGDRVDG---GRKVRVESGYFSLEKA--------KQDLRAEEQ-LPPLLSPPSPSTP---------HSRRSQVIEKFEALDIEKAEHMETNMLILTTPS------SDTRQGRSERRAIPRKRDFASETPTAPLSDA--CPLSPHRRAKSLDRRSTESSMTPDLLNFKKG------------------------------------------WLTKQYEDGQWKKHWFVLADQSLRYYR-----------DSVAEEAADLDGEINLSTCYDVTEYPVQRN------------YGFQIHTKEGE-FTLSAMTSGIRRNWIQTIMKHVLPTSAPDVT---------------------------SSLPEGK-NKS-TSFDTCLRPSEKQEAEPGEPD----------PEQKKSRARERRREGRSKTFDWAEFRP-------------------IQQALAQERASTVGSSDSGDPG-------CLEAEPGELERERARRREERRKRFGMLDTNDGPG---------MEDTALRMDIDRSPGLLGTPDLKTQN--VHVEIEQRWHQVETTPLREE-KQVPIAP--LHLSLEDRSERLST-----HELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVAL-------------------GREQSAREGYVLQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSD---IEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTREGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSG-YDIMKSKSNPDFLKKDRSCVTRQLRNIRSK--------------------SVIEQVSWDN---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97434-1", "uniprot_id": "MPRIP_MOUSE", "id": "P97434-1", "name": "Myosin phosphatase Rho-interacting protein", "aln": "------------------------------MSAAKENPCRKFQANIFNKSKCQNCFKP-RESHLLNDEDLTQAKP---------IYGGWLLLAPDGTDFDNPVHRS--------------------------------------RKWQRRFFILYEHGLLRY------------------ALDEMPTTLPQGTIN------------------MNQCTDVVDGEARTGQKFSLCILTP--------------DKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSSGSSSS-----IPSAEKVPTTKSTLWQEEMRA------------------------------------------------KDQP----DGTSLSPAQS----------------------------------------------PS--QSQPPAACTP----------------------------------------------REPGLESKED-----------------------------------------------------------------------------------------------------------------------------------------------ESTISGDRVDG---GRKVRVESGYFSLEKA--------KQDLRAEEQ-LPPLLSPPSPSTP---------HSRRSQVIEKFEALDIEKAEHMETNMLILTTPS------SDTRQGRSERRAIPRKRDFASEAPTAPLSDA--CPLSPHRRAKSLDRRSTESSMTPDLLNFKKG------------------------------------------WLTKQYEDGQWKKHWFVLADQSLRYYR-----------DSVAEEAADLDGEINLSTCYDVTEYPVQRN------------YGFQIHTKEGE-FTLSAMTSGIRRNWIQTIMKHVLPASAPDVT---------------------------SSLPEGK-NKS-TSFETCSRSTEKQEAEPGEPD----------PEQKKSRARERRREGRSKTFDWAEFRP-------------------IQQALAQERASAVGSSDSGDPG-------CLEAEPGELERERARRREERRKRFGMLDTIDGPG---------MEDTALRMDIDRSPGLLGTPDLKTQN--VHVEIEQRWHQVETTPLREE-KQVPIAP--LHLSLEDRSERLST-----HELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVAL-------------------GREQSAREGYVLQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSD---IEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSG-YDIMKSKSNPDFLKKDRSCVTRQLRNIRSK--------------------SVIEQVSWDN---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6WCQ1-1", "uniprot_id": "MPRIP_HUMAN", "id": "Q6WCQ1-1", "name": "Myosin phosphatase Rho-interacting protein", "aln": "------------------------------MSAAKENPCRKFQANIFNKSKCQNCFKP-RESHLLNDEDLTQAKP---------IYGGWLLLAPDGTDFDNPVHRS--------------------------------------RKWQRRFFILYEHGLLRY------------------ALDEMPTTLPQGTIN------------------MNQCTDVVDGEGRTGQKFSLCILTP--------------EKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSSSSSSSSSSS------IPSAEKVPTTKSTLWQEEMRT------------------------------------------------KDQP----DGSSLSPAQS----------------------------------------------PS--QSQPPAASSL----------------------------------------------REPGLESKEE-----------------------------------------------------------------------------------------------------------------------------------------------ESAMSSDRMDC---GRKVRVESGYFSLEKT--------KQDLKAEEQQLPPPLSPPSPSTP---------NHRRSQVIEKFEALDIEKAEHMETN-AVGPSPS------SDTRQGRSEKRAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKG------------------------------------------WLTKQYEDGQWKKHWFVLADQSLRYYR-----------DSVAEEAADLDGEIDLSACYDVTEYPVQRN------------YGFQIHTKEGE-FTLSAMTSGIRRNWIQTIMKHVHPTTAPDVT---------------------------SSLPEEK-NKSSCSFETCPRPTEKQEAELGEPD----------PEQKRSRARERRREGRSKTFDWAEFRP-------------------IQQALAQERVGGVGPADTHEPL-------RPEAEPGELERERARRREERRKRFGMLDATDGPG---------TEDAALRMEVDRSPGLP-MSDLKTHN--VHVEIEQRWHQVETTPLREE-KQVPIAP--VHLSSEDGGDRLST-----HELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVAL-------------------GREQSAREGYVLQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSD---VEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSG-YDIMKSKSNPDFLKKDRSCVTRQLRNIRSK--------------------SVIEQVSWDT---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9V7-1", "uniprot_id": "A0A8M2B9V7_DANRE", "id": "A0A8M2B9V7-1", "name": "", "aln": "---------------------------MAQSTSAKDNACRKFQANIFNKSKCQNCFKA-RDAHLLSDEDFTQAKP---------IYGGWLLLAPEGTNFDNPLHRS--------------------------------------RKWQRRFFLLYEHGLLRY------------------ALDDMASTLPQGTIN------------------LNQCVDVVDGESRTGQKHSLCICTP--------------DKDHYIRAESKETIHGWQEALMVFPRTNKQNQKKKRKVETPTPQEPGPAKVTVTSTSSSSSMVCLP---STIAHAERVPATRTTLWQEETWS------------------------------------------------RATLPTSCSTGSLSQLDSGNSN--------VGRKPRVESGYFSLEKPKIEDEGQQYHLQQEEEPPSKLQSHPPELSSSSSSSSRSRYLSFDPELYSSPISSHKHTSHDPHSTVHTQASSVVCDAHKHNMQSKSEKHLSQSSEILSDSTLNRDSNIYSPNPHANVLPSS-----------------------------------------------------------------------------------------------------LSSSQSSLDSEQSPESVVGGALGRAGRSGCGYVALADVPRARRLSHRDAYRCSQKRQELRARTRSPGREEVERLFGC-QRRRSQVIERFEGQDTVNAPEQMDTTSSSTDPAPSYSKTANQRAGRNEKRLSNQKQEFSLDSAKCRTDEV--SSLAGYRRAKSLDRRTTETLMTPDLLNFKKG------------------------------------------WMTKLYEDGLWKKHWFVLTDQSLRFYR-----------DSIAEEASDLDGEIDLSLCYDVTEFPVQRN------------YGFQILSKEGA-FTLSAMTSGIRRNWIQAILKNMRPTVAPDVTRKNVSLKLSV--------------LMPSSLPDER-TRSNVEQSFIQPPSQLSNSSIVEPKRPHEDITDSAPPPDQRKSRGHKREGRSKTFDWSEFRPGQENESGQPSLKRADTSVIISSSPSSIASSPISSSSSHQTSSSITIISHTEKLPQHNEEEEQVVQEYVPHHQTVPTTMTGPETPSNPHNVPQEPAGIDLNQSREVQEVDGHGVIRKNSDVQVEIEQRWHQVETTPLREE-KQVPIAGGSPNVSNVSVGERASP-----QEKTSKLEKELGQAQKELARLQEQNSILQDQLQDAR-------------------GREQNAREGYVLQNDSTIAKPSSDAPVSTTVHKAPWQRLSKLNQDLKSELESQRRKQDKAKHQVSSLRRSYSEAKDIIGHHEAEIEALEEKLTAAMAEIVVSEQAVARMRSDLKIERVRCQEREEEWTRNETTLRSQLQDSEERLRQVEASLLEKNQELRQLEQQQALQRDQHREMQRLQERLAEATGRLISMEESQTMREERERKEHRSLEEKHERERQGLTRRLAESEERRQEIEEQLQEAQEQVEALLRGSSGMETVGLREQVHRLQQELETQTDMVEMLRESVRRLEEERDQLTCRCQELLNQIAEADREVGKQQACLTTVETDFHSLETSYEHVSEEFARISHVLQEKEEEVRQTKEMYEHLIRQKEQDLSEALIKMAALGSSLEETELCLQQKEELLSKMERDYPGLVESRKAEQELQAKLVVAEDRIAELEEHLNALRLGYADLRMRRCRSQEDMLESLKEIEHEVSLSSSTSQLLARSSSETEMSLVKRQRIRFSTIQCQTYHRSQGADKFQTENTSLDLTQDLSLDHMHDLSLTQDISVVSDNSFQQCRDPEKFISIIHALETKLLATEEKLRHLTDKIRDQPNLSAVQEHLSTRATMEDWTTKTCDDLPMDEPSQKHLNKTVSEHDSGEYEKALALVESCTERVREILSNQNETSSAESLICTLAEVEKRLVCATAFLRKGHTLYESCHVFDAPDVQSMKGSIKLFARTLCFEAEVLEKMGFSLQDLNSDIMAALNSIHKEAENIKKSCDGCLSVVYADLLTRKLLLETMFMSEIDKLETGNLANSGFSQDAIKSACISAELAYSLQNLTTNFQERFDELQKDLIQANKTLKQRDFALKDAVSASKHSCIESIPQSTTDHLVGDDAPPELVPYMEQIEMEEAQSLAAEIVRRHLTGGMLSHSAESESHLQMGWENLIAELKKQAKALRNISQEIEKICETGEMNSLSRLAEAIQLSSYRSDSSSVCMREALMQVQVAYVSCRLRAGHTRELSLCQETSRNMSALVQEHAESVAAIQKHYQSCLEKEHLSFTGTISSLQEENDMLRGELSYKLRELQEQRQNLSQLEEAFHREKEELKCKHADEFGRAEQEQMTRELELMDRAASSQRKLETLLIEMEDSELKHKEQVQKLQLEFQGRIQELEHANREELCKLKKSYSQTICFLENKGEADACPMEEGEGSDSVTCKESLLRVRELEMQLSNMREELEQKPLDGDLTSLREKYQRDLDSLKATCERGFAAMEETHQKVIEDIQRQHQREIQKLLEEKERLLEEETNATIAAIEAMKNAHREELE----KTQRSQMSGVSAD---IQELHRQYEEELQSIHRELEVLSEQYSQKCLENAHLAQALEAERQALGQCQRENQKLHIHNQELNHRLNEEITRMHSCIS----GEKNTSSLTQGKDIYELEVLLRVKESEIQYLKQEINSLKDELQSALRDKKYASDKYKDIYTELSIVKAKADCDINKLREKLLAATEALGELDAEGSGVTAGYDIMKSKSNPDFLKKEK---SRQMRGVRSK--------------------SLKEGLTVQERMKLFEAKDSRKI--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GWG1-1", "uniprot_id": "A0AC58GWG1_DANRE", "id": "A0AC58GWG1-1", "name": "", "aln": "------------------------------MSSAKENTCRKFQANIFNKSKCQNCFKP-RELHLLTDQDLNQAKP---------IYGGWLCLAPEGTDFDNPMQRS--------------------------------------RKWQRRFFVLYEHGCLRF------------------ALDESPSTLPQGTVN------------------MNQCTDVVDAEPRTGQKNALCIVTP--------------EQEYFIRGDNKEIINGWSEQLAVYPRTNKQNQKKKRKVEPATSQEPGPAKVAVTGAG--------------IPDAEKTPDSSSIIWQEELQS------------------------------------------------READAAHTWSSEIPPVGS----------------------------------------------PLPSTGEGSTVSSVNGDEVDRCGLSFHSPVSQAPVDPLSPTG------------------SSSSRQSAETG----------------------------------------------------------------------------------------------------------------------------------------GVPRCLSPAPSDPFPSGSSLLSNGSHISGSMSSLDSEASGSTVTSSDSHPPEPRALKRSRLRSPQTRERELVLSPERSGRSNVIEKLEALELEQQERMEVQESSSTEAR----------QGRSQNRRFQR-QEQKTDAAQALDFHP------PLRRAKSLDRRTTESVMTPDLLNFKKG------------------------------------------WMVKLDEEGQWKKYWFVLTDHSLRYYK-----------DSIAEEASDLDGEIDLSTCYNVTEYQAQRN------------YGFQIYTQEAV-HTLSAMTAGIRRNWIQAVMKNVRPATAPDVA----------------------------SLTDEHGSFEGVCRPDVTQDSPSSEASVERET-----------GAKKSRARERRREGRSKTFDWAEFRP-------------------IAQALAQQRAQEAELT------------------------ERSKRREERRRRY---ESVTGAT---------FDPALMEQEGGVAQTEAPPLSAEWQQR-VEDEIEQRWQQVEKTPIRDE-RRVPLGS--AHSRDATDMEKLLEGY---KRGVEELKAQLENCHQQLLDSNRHKQDLEGKLKMAV-------------------EREQQTRAGYISPLESPLSVETEPQMKRTELVSSQAQSLTKKYQETKELLQLQELKKRDMQAQLG-------------------------------LSLSHWPAKDPSLSDTQKHEVCPSKCTRRTLTLTLQDSEGTIRELEHLINTDDPLTLREFIKLVQLHSEHVCVVESPPGMEQSEHSRSVGAECQKLLESLKNQQEMESEAVRRSLEKAGDCIRDYEARLLTMEDMLGRAQQQKAEILLQSPSRVEEFSADMSSRDLSQQVGILANENVALNQRYQEIVNQLREADREIDRLKAEVYRLRHSKEDDEESADKRE------------------------------------------------LCEKSHKLQEALIKLETLGSNLKDTEKRLQLKEATLRGLGFQVAESEAEDDLKCQLEILQCKLSEKEKMCEELQSQNPRQEDAVRLNQMLVEAQEEIAGLKRKLESRAGFSSESEFMEEEGASELKRKSESLMLVFGALVNGREAECDAFIVDEDHAGLMTERRILCRIVDG----------------------------------LQKDEQSVRQVVERMMEDNNMLIHANKLSDIQPGETMHDEDDADIMKSLSEAVQSKVALLNQTSLARTGDKLTLRSRSDYIREAITDITHMYQTLRLKKEFARAEMR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQQELAVTRIHIEGEPIDSLDKSIQLQDLMARHKKELRELKEVYETDVEKLKKELEKAGETLKMRSEENVREIDSLTVCMENLEKKHEAERRELQTRFSLQMEELWEAVGFEDKDWSSGSLKEQILKLVRRESELTQLMHQKDGD------------------------------------LRLRYEKDLEKLKATCERGFAAMEESHQKVIEELQKKHQRELEKLQEEKERLLEEETAATIAAIEAMKNAHRSELERELEKARKATSSTENAD---IEEIHKQHEEELVSYQREIEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITKMRSMATEDG---ADTGGLIQGKELYELEVMLRVKESEVQYLKQEINSLKDELQTAQRDKKYATDKYKDIYTELSIVRAKAERDLGRLREQLQLAHNALGEPTLEDMERGG-YDIMKSKSNPDILKMAAAAAKRSERTMRSKLIVDEGLFMSSHGSSDAGRSSLKEGLTAEQRLHLFDNKDTKDF--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B0C4-1", "uniprot_id": "A0A8M3B0C4_DANRE", "id": "A0A8M3B0C4-1", "name": "", "aln": "---------------------MTRLEASLQRSESRSVIEMPSRRESANASRRGSISMSRRESVSQQHSETRRETE---------QSNGRGIFKRANRFLSQDREQD--------------------------------------DGSSSSPVRHYERGHALP----------------ANHSPERKAAIPFRNPDLG-------------LPSYRRRYDNLSEQAISGLSPQRHMSYS-----------------NFRRGDSQSRASPRSGSPRSTNISPQRRGESRSSSYRRGSSTHGHRMSSQQASGKCTPSRRRDS--IATRTSSPSRSSGTNKYADSYSP-----------------------------------------------AHKRSPSQSSYGHSLDSEK---------------------------------------------LYKNLKSIVSSAESDGYD-------------------------------------------ERNGWSKRIQS---------------------------------------------------------------------------------------------------------------------------------------------DDGGYNERNHSGRSSRKSGSHRSGYNSRDFSPTGSNCDTIKSRNTGRNSRNSGASTPHRNYDERDTVKNSTSKNKSRRNEVYSDISDKQSKSDSRQSLSPTHSP-------LSPTSPASTPSIAQSRRSRNQAPTPDLTKSQTLTPETDKPAIDRSRSNIRRGLEALILSENPR------------------------------------------SSSQPAVPEMTIEDYVIIADIPRSKLY------------PEEEEAIIVRRRPQSRSPRRDNQHSYEDGR-----------YGYEHEVSEER-GRGRERERGRDRREKERRRLDKEMGGSSKAN-------------------------STTSGHSQKSNKNGDIRMTNGGHRGQEKPPPMQGWMYLLDEDEEWRKFWFVITDSGLRYYRDSEAEERDEADG---------EVYLRHCLRVEEFDADKNYGLQLHMRDGLVTLS-----AMTSRIRRNWIDTLRRKISFRDSADSIQHLDNSDISDRENSSSQNAPSQTSPAPREPCSDDGGLYEDEPDITCSPLTNRREAGEGRDREHERRLEDRTKWFQEGVSDREGDDPWDKVELKKGGTPVVLTQLQVPKAKTGPDIEKKWEDFEQLPIGE-------------------KRSLVGSQNPQAANEALQREVLSLRQQIESLRQVRVGALCGP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAPCALRLQQMEEEHRERLKEIHEQHERERRDMETEKQRLLQEEAKNTLQAMEALRKTHQEEIERLKGHGGEELTDPS----------IKQQLHESLSLQRELDGLSQRYSQQCVELNRIQSGTDERDGQIRQKERDMEQLRMENQELQARLTEEISLMRSFITGQR--SGVVPLGSYERSTSELEMLLKVKESEVEFLHKEISCLRKEVQTLTKENEALGERYKEVYVELSELRGRSERDINALKQHLKLTDAALEEGRLLGNSDNQ----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27421-4", "uniprot_id": "OSP_DROME", "id": "Q27421-4", "name": "Protein outspread", "aln": "MSTTTITTTVPAAPSKSAPPTPTTTGAAGATTNARTADCRKFTPNIFNKSKCSHCFRQREEHSAAALECNRRTSSNLAEPASRKVSKCGYLFVAPDWDFSNPLYRT--------------------------------------KRWQRRWFVLYDDGELTY------------------SVDDYPETIPQACVD------------------MTKVLEVTSAVEVTGHPNSIAITAP--------------ERVTFVKGTSSEESQWWLNILAAFPKSKGRHKRSATLPGGQVVGSLRPTSNGDLTLSTKLGNRHSSYHKDTLTSSQSAGNLLSSLDLGPSST-----------------------------------------------KTAGSPLTTTQSALADDEEDDGVETG---------------------------------EDVDEDEEDETSVPRKSKTVSMGGQDENNRNAGNEITNRVSQPTTCLLIEDIRR------------DEKTIKDIAN---------------------------------------------------------------------------------------------------------------------------------------------TITNLSQQQNKRWSTAVNNALNNQHHFGHHSQYQVTSRDETDFQMSSNSSSTKSQNPASERPKSLPLASNSTPAIVSAIVKKIPTVMEQGDKTKPTARLQLHLKS----------PKHYQHERGDPDGGCNLDELCVNYMAKTDELRSVGKANSKSSSGQGKPPVKEESLNAKKG-----------------------------------------WLMKQDNRTCEWSKHWFTLSGAALFYYR-----------DPLCEERGVLDGVLDVNSLTSVIPEPAASKQ-----------HAFQLTTWDKQRLVLASLSPSSRNSWLAVLRSAAGLPQLDTPPKQTDIEQDFIKAQLQ---------QPSSSPVTPGTPAGPHFSSDEEYRTASEGGRRDSLDWGSPLSPSPPVLRSCLRNRSLASLHKRSRSSPPSSRRSTVDSVASDELPLLVVPEEMQPTESRELKQQCETLRAEASLREARMSELLATLQRTEQQLTARLQEQQQQLNSELTQAKQSASDLMHNLGMQLTESQCQIKQLEDRLAQGIEENEGLYKRLRELQAQDHSGGAALSNLQRHKIKRMDSLSDLTTISDIDPYCLQRDSLAEEYNELRSRFEKAVNEIRAMKRELKQSQNQYDALELAQAALQQK---------LERRQHEDGAQLQLMAARIQDLTLKYSSSERQVRALKQKLAKSERRRSLSLKGKEQLELKLSELQR--------------------------------------------ETVERKEGTPPESSSSESSSQSPLNAHLLQRLHSLEHVLLGSKERLEQSLTQLQQIRAGQRTRRSVSPMNDRKDGLRQLERALAETCVMVSEQMELTCLQDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHKCCDLRQRVEKLSALQQQTETDLQRSEQLLEQRETDLAQALEKCASQEQEQELLLQQRQELSEELGRQQERCRRLEKRLELLEREHGKQLECLREVYHTEHANAADEQS---------------------------------------------------FRKRYQTEIEQLRTLCEKGLSAMETSHKRLTMDLEQKHKMEIERLLAEKETALAEETQATLAALDAMRKAHQSEVQREVARFKQEFLRQVQRGEQMRGDGAKLKEEDLGELRMEILAFSEKYSIKCVENAALEEKLHMANSKLRHFQQ-MQQLELRNKQFRAHLASDDPSNDVHFVQGLTSDAREDADCEDSEPAPQILGATATRTTATTTTTATATTTSAAPSETESNPDSDRETADSSRAPPEKMEQSLFVIPSHMLNSSLVPAANASDQSQRSQLYRDLDGPEDGYEPCYRPFDIFAIYQNRLSYQGLKGSSTFGKSLRKSAAQTSPASSEITTTTTAPTTDPKKPSHKQMFKTAAVINIQQQVAQEEKAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : .: * * . * : . * . . .. .. . . . . . . . : . . : : . : .: : . : : . : : : . : . : : .. . . * * : ** *:. ::..:*: * . : **: * **: * *::*::::::.*:. : : : : *: :*::** :*:* : . : :: ::* .*:::. :* : . : .... . ..: . : :: : : . * . ", "identical_positions": 30, "similar_positions": 114, "identity": "1.02%" }, { "cls_id": "homologset.agr.FB:FBgn0003023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LA32-1", "uniprot_id": "A0ABK0LA32_RAT", "id": "A0ABK0LA32-1", "name": "OTU domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAAVGAPDGVDQGGAGPLEDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIRYLRDNREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFVIYQEPNVSPSHVTENNFPEKVLLCFSNGNHYDIVYPITYRDSSAVCQSLLYELLYEKVFKTDVSKIMMGLETSEVADESN------------SEISDSEDDSCKSK-STAATDVNGFKS-SGSENPKNHGNSADLPLSRKVLKSLSPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEGGERCHQVRLDHNGKLSNADIHGVHSENG--PVLSEELGKKQTPKNL----KPPPPESWNTVSGKKMKKP-----NSGQNFHSDTDYRGPKNLNKPIKAPSALPPRLQHPPAGVRQHALSSHSTGPQSQKSSSEHKNLSRVPSQITRK------------------PDRERAEDFDHVSRESYYFGLSPEERREKQAIEESRLLYEIQNRDE--------------------QAFPALSSSSVSQSP-QNSNACVPRKSSHARDRKGSMRRVDAEERKDKDSLRGHTHMDKKPEPSTLE-ISDDKCTRVSSPSKSKK--ECPSPVEQKPAEHIPLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPILSVTQ--TTGPDAAVSQAHLTPSPVPVSIQAVNQPLMPLPQTMSLYQDPLYPGFPCSEKGDRAIAPPYSLCQTGEDLPKDKNILRFFFN---------LGVKAYSCPMWAPHSYLYPLHQAYMAACRVYPKVPVPVYPQS--TWFQEAPPAQSESDCPCADAHYSMHPEASVNG-------------------QMPQAEIGPPAFSSPLVIPPSQVSEGHGQLSYQPELESESPGQLLHAEYEESLSGKNMYPQQSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFVENPVMR------QNIVLPPDDKGELDLPLENLDLSKECDSVSAVDEFPEARVEGAHSLSEASVSSK-HEGRVEQSSQTRKADIDLSSGSSGVEGK-------------AHPPTQILNREREAVSAEPEPKRTIQSLKEKPEKVKDPKTAADVLSSGANSVD-RLQRPKEESSEDENEVSNILRSGRSKQFY----------NQTYGSRKYKSDWGSSGRGGYQHVRGEESWKGQPNRSRDEGYQYHR---------------------HVRGRPYRGDRRRSGMGDGHRGQHT-----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RRE7-1", "uniprot_id": "OTUD4_MOUSE", "id": "B2RRE7-1", "name": "OTU domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAAVGAPDGVDQGGVGPLEDETPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIRYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFVIYQEPNVSPSHVTENNFPEKVLLCFSNGNHYDIVYPITYKDSSAMCQSLLYELLYEKVFKTDVSKIMMGLEASEVAEESN------------SEISDSEDDSCKSK-STAATDVNGFKP-SGSENPKNNGNSADLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCHQVRLDHNGKLSNADIHGVHSENG--LVLSEELGKKHTPKNL----KPPPPESWNTVSGKKMKKP-----NSGQNFHSDTDYRGPKNLNKPIKAPSALPPRLQHPSSGVRQHAFSSHSTGSQSQKSSSEHKNLSRMPSQITRK------------------PDRERAEDFDHVSRESYYFGLSPEERREKQAIEESRLLYEIQNRDE--------------------QAFPALSSSSVSQSPSQNSNACVPRKSSHARDRKGSMRRADAEERKDKDSLRGHTHVDKKPEPSTLE-ISDDKCTRVSSPSKSKK--ECPSPVEQKPAEHIPLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPILSVTQ--TTGPDAAVSQAHLTPSPVPVSIQAVNQPLMPLPQTMSLYQDPLYPGFPCSEKGDRAIAPPYSLCQTGEDLPKDKNILRFFFN---------LGVKAYSCPMWAPHSYLYPLHQAYMAACRMYPKVPVPVYPQN--TWFQEAPPAQSESDCPCTDAHYSLHPEASVNG-------------------QMPQAEMGPPAFASPLVIPPSQVSEGHGQLSYQPELESENPGQLLHAEYEESLSGKNMYPQQSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFVENPVMR------QNIVLPPDDKGELDLPLENLDLSKECDSVSAVDEFPDARVEGAHSLSAASVSSK-HEGRVEQSSQTRKADIDLASGSSAVEGK-------------GHPPTQILNREREPGSAEPEPKRTIQSLKEKPEKVKDPKTAADVVSPGANSVD-RLQRPKEESSEDENEVSNILRSGRSKQFY----------NQTYGSRKYKSDWGSSGRGGYQHVRGEESWKGQPNRSRDEGYQYHR---------------------HVRGRPYRGDRRRSGMGDGHRGQHT-----------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01804-1", "uniprot_id": "OTUD4_HUMAN", "id": "Q01804-1", "name": "OTU domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAAVGVPDGGDQGGAGPREDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIVMELDTLEVADEDN------------SEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKC-QVRLDHNGKFLNADVQGIHSENG--PVLVEELGKKHTSKNL----KAPPPESWNTVSGKKMKKPS----TSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHP-SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRK------------------PDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDE--------------------QAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKL-ECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFN---------LGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHN--PWFQEAPAAQNESDCTCTDAHFPMQTEASVNG-------------------QMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMR------QNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGK-------------AHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILRSGRSKQFY----------NQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHR---------------------NVRGRPFRGDRRRSGMGDGHRGQHT-----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D8C3-1", "uniprot_id": "ALG13_MOUSE", "id": "Q9D8C3-1", "name": "UDP-N-acetylglucosamine transferase subunit ALG13", "aln": "MKRAFVTVGTTSFDELVARVVANDCVQILESLGYNHLVLQVGRGTVVPKPFRTESFTLDVYRYKDSLKEDLQQADLVISHAGAGSCLESLEKGKPLVVVVNEKLMNNHQFELAKQLHKEGHLFYCTCRVLSCPAPVSLLLVLLGSAKILQQLPSATLS--CFGYLP--TQAPVLVATAYSYLHSVFSSFPPLSTFLIIP--CTMQKGWKKYCGQKSLNEASMDEYLGSLGLFRKVVAKDASCLFRAISEQLFHSQIHHLQIRRACVSYMKENQQAFESYVEGSFEKYLERLGDPKESAGQLELKALSLIYNRDFIIYRYPGKPPTQVTDNGFEDKIILCYSNNGHYDSVYSKEFQSTAGICQAILYELLYKDVFVVDEETLKTAVDLFRSGSRRNKHHALTASVEGSSDQKSSTEDRTEEAAACSSAASTPEGNKQGTERQKVPESPSKMLFPYKVLKALDPEIYRNVEFDAWLDSRKELQKSECVEYGGRYYFLGDKC-QVCMESGGKYYNAHIQEIDNDKSSVVVFIEEFAERHS---------------------------------------------IPLAHVRPVNQVALLPSWNAIPIRNGRGYPTITGGYFPEIVMTDMNMK---------------------------------QRKKMFKKFRGKEIYMTMAYSRG-------DPLVPSRIQHSMH--------------------YGHDPLLYYSQTAGHILSSQHFYPQHSSQRQGRGYGMPRDSSHLISKQNLPNPKVGFCSGSGRKCCQSYDNVSYRSRSFRRSHRQM-HCMNKGCQ--YGFAPENG-----VEETVTFYALE---EGNETAYSTLPNNGGPT-----------------------------------------------------TMVPATSGYCVARQGYNSCKPPLNSGDSNDHCDNGGYHGDYLYS---------SEQGYETSSVYTTTVSTANLSLQD-SGPSSVPQDTVTSYNYP--QKVLENSAAIAVSWASHVPVPVIPNCAGDNEA-------------------LRTSDISSQNAIQPGFVPPPAQGSPAYLEPSAAGAAGAAAAAAAAAAPVATPVAA----------PLPLPPPLPPPPPATLEAGDASGFPLPPPPPPPP------PPPPPYSYDPSGSDLPQDTKVLQYYFNLG-----LQCYHHNYWHPMVYMPHVQQQLQPQPQPQPQPQPQPQPQPQPQPQQPQQ-------------QQPPPQQQQQQQEQVHGESYPDCTEQPLVDQS----APQVYSDVVREDG--------TQADVSTNDTFPIADAVPLPHGAVYY----------PVMTDPYG-SPLLGFDSYVPVASDYSSIAMWHPVNAACGASAQIHG---------------------AMNPGPIGYMLL-PNSPHYTPQN-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP73-1", "uniprot_id": "ALG13_HUMAN", "id": "Q9NP73-1", "name": "UDP-N-acetylglucosamine transferase subunit ALG13", "aln": "MKCVFVTVGTTSFDDLIACVSAPDSLQKIESLGYNRLILQIGRGTVVPEPFSTESFTLDVYRYKDSLKEDIQKADLVISHAGAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEGHLFYCTCRVLTCPGQAKSIASAPGKCQDSAALTSTAFSGLDFGLLSGYLHKQALVTATHPTCTLLFPSCHAFFPLPLTPTLYKMHKGWKNYCSQKSLNEASMDEYLGSLGLFRKLTAKDASCLFRAISEQLFCSQVHHLEIRKACVSYMRENQQTFESYVEGSFEKYLERLGDPKESAGQLEIRALSLIYNRDFILYRFPGKPPTYVTDNGYEDKILLCYSSSGHYDSVYSKQFQSSAAVCQAVLYEILYKDVFVVDEEELKTAIKLFRSGSKKNRNNAVTGSEDAHTDYKSSNQNRMEEWGACYNAENIPEGYNKGTEETKSPENPSKMPFPYKVLKALDPEIYRNVEFDVWLDSRKELQKSDYMEYAGRQYYLGDKC-QVCLESEGRYYNAHIQEVGNENNSVTVFIEELAEKHV---------------------------------------------VPLANLKPVTQVMSVPAWNAMPSRKGRGYQKMPGGYVPEIVISEMDIK---------------------------------QQKKMFKKIRGKEVYMTMAYGKG-------DPLLPPRLQHSMH--------------------YGHDPPMHYSQTAGNVMSNEHFHPQHPSPRQGRGYGMPRNSSRFINRHNMPGPKVDFYPGPGKRCCQSYDNFSYRSRSFRRSHRQM-SCVNKESQ--YGFTPGNGQMPRGLEETITFYEVE---EGDETAYPTLPNHGGPS-----------------------------------------------------TMVPATSGYCVGRRGHSSGKQTLNLEEGNGQSENGRYHEEYLYR---------AEPDYETSGVYSTTASTANLSLQDRKSCSMSPQDTVTSYNYP--QKMMGNIAAVAASCANNVPAPVLSNGAAANQA-------------------ISTTSVSSQNAIQPLFVSPPTHGRPVIASPSYPCHSAIPHAGASLPPPPPPPPPP----------PPPPPPPPPPPPPPPPPALDVG--ETSNLQPPPP------LPPPPYSCDPSGSDLPQDTKVLQYYFNLG-----LQCYYHSYWHSMVYVPQMQQQL-------------------------------------------------------HVENYPVYTEPPLVDQT----VPQCYSEVRREDG--------IQAEASANDTFPNADSSSVPHGAVYY----------PVMSDPYGQPPLPGFDSCLPVVPDYSCVPPWHPVGTAYGGSSQIHG---------------------AINPGPIGCIAPSPPASHYVPQGM------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P7L2-1", "uniprot_id": "A0A8M1P7L2_DANRE", "id": "A0A8M1P7L2-1", "name": "OTU domain-containing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELRAASADAQQQLAGDRTHESRMDEYLRSLGFYRKKIAKDGSCLFRAVAEQILHCQGLHTQVRAACVNYLRQNRPTYELFIEGNFEKYLENLQDPQSWVGQVEISALAELYKHDFIIFQEPDQPPVNLTENGFTHKVRLCFLNGNHYDSVYPESFEKNAAVCQSILYELLYERVCGVERNVVGSCVKGGRGRDRQDSEECKS-----SEESELEEDDFWSTEPREKTSNGMNARPPQRGRGRGYSRGRGREFLSTKVQKSLNPTLYRNVEYDVWLRSKRLQQQRDFCIAAGMQYSVGDKC-KVQLSGSNRLYSAYVKEVSPDNGPVTVFIEELNKQQTVPLLNLRLPSEEPQSWHTVSERGKRQAAPNNEWESRGGRRPNRMQSQSAPSVRVHKQHSWPPQATTDDARNKFSRRSDQRSSPVCILPEEEEESVVLELLHKDEHNFPSLGPSPQTATPGEVIKKGGEKKSHRKKEQKENFMETEASQKPLQRQKSGTEEKHGIKFSEEPRQRSSSTINEKLQEKPIPVAASPPSPAIFLSGPKTPISSSNSATSPDPNRSAPEAVKKATIQPKSSPAQNPDNSHLEPVSTLASLQHISRVAPVSETTPASQFISGAAPVSVVPPASQSISATTPAPQSISAAAPVSVSTPASDSILVAAPDSATTPASQYIPGSRAVSVSTPAPQSISGATAVSSNTPTPHSISRATAVSVTAPAPHFTFVATAESISTPSPHSISGATAVATPAPIQSAPALNSTKPSFQMAQLPTVELLPRTEAPSQFTSVELVASQITLVPLPTSTPTQTTLAPTCPIPAAPVESSLCIQTLPPANTSTLSPTPSSTIPISAQAQVATPVLDSPGLSSTPHPIHANNAPPIPKKTVDPQTTMMPVPLPHAAPTSISPSIGSANASPPDLPLVSPKESVPSACETSTIPASGAAPVVDHPSQPQHLPFPQVQWSQLLQDPVYPGFPQNEKGQLEPPPPFSYSQKGEDLPKDISVLKFFFNLG-----VKAYTQPMFPPIVYLAPLNQAYLRGPSPSSDSPANPTITSWQPENPSSQPQSLSSMVDTPLDSHAPIAPVAAGSSPVDPIEVRGYNDPPSIPMHVPPRPPMPWSAPSVSSAYPGGYPTTPPVQFSTPPYPPPGNQMYPPSSVGYHRMPFPPMPLEAINHGPHGPIDVLPFARPTLERGQENGQLSINPQFRSVQNSAGFPGGQPHFLSGVDFKSVDTPVSLGGMEPPPYGGHCSVPSFQIGPLQGDMSGLIPLPNGSLGRQGGAFPKNLHAEDSSRLVHTFSPEEKWPEEMESTNVDLRVPQLYYSHSYRGGGRRGQEDRGGYRGRSQRGRKDYIGRGRQDDQSYRHYGRRGAGPQLPYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10383-1", "uniprot_id": "OTU_DROME", "id": "P10383-1", "name": "Deubiquitinase otu", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDMQVQRPITSGSRQAPDPYDQYLESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMTLKRRIFEKEIPGDFDSYMQDMSKPKTYGTMTELRAMSCLYRRNVILYEPYNMGTSVVFNRRYAENFRVFFNNENHFDSVYDVEYIERAAICQSIAFKLLYQKLFKLPDVSFAVEIMLHPHTFNWDR--------------FNVEFDDKGYMVRIHCTDGRVFKLDLPGDTNCILEN-----YKLCNFHSTNGNQSINARKGGRLEIKNQEERKASGSSGHEPNDLLPMCPNRLESCVRQLLDDGISPFP-------------------------------------------------------------YKVAKSMDPYMYRNIEFDCWNDMRKEAKLYNVYINDYNFKVGAKCKVELPN-----------------------------ETEMYTCHVQNISKDKNYCHVFVERIG-----KEIVVPYESLHPLP-------------------------PDEYRPWSLPFRYHRQMPRLPLPKYAGKANKSSKWKKNKLFEMDQYFEHSKCDLMPYMPVDNCYQGVHIQDDEQRDHNDPEQNDQNPTTEQRDREEPQAQKQHQRTKASRVQPQNSSSSQNQEVSGSAAPPP---------------------------------------------------------TQYMNYVPMIPSRPGHLPPPWPASPMAIAEEFPFPISGTPHPPP--------------TEGCVYMPFGGYGPPPPGAVALSGPHPFMPLPSPPLN----VTGIGEPRRSLHPNGEDLPVDMVTLRYFYN-------------------------MGVDLHWRMSHHTPPDELGMFGYHQQNNTDQQAGRTVVIGATEDN---------------LTAVESTPPPSPEVANATEQSPLEKSAYAK------------RNLNSVKVRGKRPEQLQDIKDSLGPA----------------------------------------------------------------------------------AFLPTPTPSPSSNGSQFSFYTTPSPHHHLITPPR-----------LLQPPPPPPIFYHKAGP----------------PQLGGAAQGQTPYAWGMPAPVVSPYEVINNYNMDPSAQPQQQQPAT----------------------LQPAPLSVQSQPAAVYAATRHH-------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** . *::** *:*.*.***.::**: * * ::* *: :: :: :* : *.*:.*:: : .*: *: *:: :*.::.:::. . . : :. : .:. : : . .*:* ** : . :.:**:: :::**: : . : . : : : . :: . *.. * :. :: . * : . : . : . : . : : .. : . . : . : . : . . : . . * . . : . * .:. . . . .. . . . . . . : :. . . . * .. .. : :. * . ", "identical_positions": 41, "similar_positions": 139, "identity": "2.62%" }, { "cls_id": "homologset.agr.FB:FBgn0003028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A445-1", "uniprot_id": "D4A445_RAT", "id": "D4A445-1", "name": "Putative transcription factor Ovo-like 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKP---------------------CVSTCKRNWSELPDEERGEIYVPVSLGF---------------------------------------------CPPQPYLEP-EASVAEPPSCP---LALDMSLRDSSYGVASG--------------------PCE--VAQLP--------------------------------------------------PEDVNHLTDPQSRDQGFLRTKMKVTLGDSP---------------------------------------------------NGDLFTCHICQKSFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKEHHPDSPLLR-KTSKKVAVALQNTVTSLLQ-GSPHL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTJ2-1", "uniprot_id": "OVOL1_MOUSE", "id": "Q9WTJ2-1", "name": "Putative transcription factor Ovo-like 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKP---------------------CVSTCKRNWSELPDEERGEIYVPVSLGF---------------------------------------------CPPQPYREP-EASVAEPPSCP---LALDMSLRDSSYSVAPG--------------------PCV--VAQLP--------------------------------------------------SEDVSHLTDPQSRDQGFLRTKMKVTLGDSP---------------------------------------------------NGDLFTCHICQKSFTHQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKERHPDSPLLR-KTSKKVAVALQNTVTSLLQ-GSPHL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14753-1", "uniprot_id": "OVOL1_HUMAN", "id": "O14753-1", "name": "Putative transcription factor Ovo-like 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKP---------------------CVSTCKRNWSELPDEERGEIYVPVSLGF---------------------------------------------CPPQPYREP-EPSVAEPPSCP---LALNMSLRDSSYSMAPG--------------------PCV--VAQLP--------------------------------------------------SEDMGHLTDPQSRDHGFLRTKMKVTLGDSP---------------------------------------------------SGDLFTCRVCQKAFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKEHHPDSPLLR-KTSKKVAVALQNTVTSLLQ-GSPHL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W4G4-1", "uniprot_id": "F8W4G4_DANRE", "id": "F8W4G4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKT---------------------GNSPGKRNWSDLPDHERGDIYIPVSM------------------------------------------------SPFAYREETEASPAEVPLCLSKRKDRNMYTHSQMYTNDPG--------------------AVVP-VAELPSCT-------------------------------------------ALGQSPETEHIRSTQN--NTYVRTKIKVTTGELPTEAPPVVPSVTTSPPVSIATHCSPPVTKPLM-----------------VQSSGATYVCQVCQKVFQFQRMLNRHLKCHSEQKRHLCDFCGKGFNDTFDLKRHVRTHTGVRPYKCELCDKAFTQRCSLESHMKKIHGVTQQYAYKERRSKLYVCEECGHTASTQDALLRHLHTEHPNSAFLRAKGARRHSPSLNGTKDDTSQPGSPLSLNSDDNAES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6GIM7-1", "uniprot_id": "A0A8I6GIM7_RAT", "id": "A0A8I6GIM7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKVFLVKRR---------------------SPGASVRSWDELPDDKRADTYIPVSLG-------------------------------------------------CLLRDPPEDCRSDGGSSSG-CSCSAGEPGGAESSSSPR--------------------APEPETPELHD------------------------------------------------AEGTDGHLAAMQR---PVARSKIKFTTGTCN---------------------------------------------------DSVIHNCDLCGKSFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCYKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSTFLK-KTSKKLAALMQNKLTSPLQENSTLSEEEEKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIV7-1", "uniprot_id": "OVOL2_MOUSE", "id": "Q8CIV7-1", "name": "Transcription factor Ovo-like 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKVFLVKRR---------------------SPGVSVRSWDELPDDKRADTYIPVSLG-------------------------------------------------CLLRDPPEDCRSDGGSSSG-CSSSAGEPGGAESSSSPR--------------------APEPETPELHD------------------------------------------------AQGTDGHLAAMQR---PVARSKIKFTTGTCD---------------------------------------------------NSVIHNCDLCGKSFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSDHPGSTFLK-KTSKKLAALMQNKLTSPLQENSTLSEEEEKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRP0-1", "uniprot_id": "OVOL2_HUMAN", "id": "Q9BRP0-1", "name": "Transcription factor Ovo-like 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKVFLVKRR---------------------SLGVSVRSWDELPDEKRADTYIPVGLG-------------------------------------------------RLLHDPPEDCRSDGGSSSGSGSSSAGEPGGAESSSSPH--------------------APESETPEPGD------------------------------------------------AEGPDGHLATKQR---PVARSKIKFTTGTCS---------------------------------------------------DSVVHSCDLCGKGFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCNVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSSFLK-KTSKKLAALLQGKLTSAHQENTSLSEEEERK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O00110-1", "uniprot_id": "OVOL3_HUMAN", "id": "O00110-1", "name": "Putative transcription factor ovo-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVRSR---------------------RPQP--PNWGHLPDQLRGDAYIPDCS-----------------------------------------------------------SLGGPPAQQ------------SSSVRDPW--------------------TAQP----------------------------------------------------------TQGNLTSAPR------------GPGTLG---------------------------------------------------------CPLCPKAFPLQRMLTRHLKCHSPVRRHLCRCCGKGFHDAFDLKRHMRTHTGIRPFRCSACGKAFTQRCSLEAHLAKVHGQPASYAYRERREKLHVCEDCGFTSSRPDTYAQHRALHRAA----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51521-1", "uniprot_id": "OVO_DROME", "id": "P51521-1", "name": "Transcriptional regulator ovo", "aln": "MPKIFLIKNRLHQQQQRLLESQNLLQHKNQDDERLVPPLSPSGSGSGPSPTPTSQPPPEPQGQGQQVLGQVPDSDQQPLSLTRKRFHHRRHYFGQSRHSLDHLNQNQSPNPNANANPNQIQNPAELEVECATGQVQNENFAAELLQRLTPNTATTAQNNIVNNLVNNSRAATSVLATKDCTIENSPISIPKNQRAEDEEEQEDQEKEKPAEREREKSDERTEQVEKEERVEREEEEDDEVDVGVEAPRPRFYNTGVVLTQAQRKEYPQEPKDLSLTIAKSSPASPHIHSDSESDSDSDGGCKLIVDEKPPLPVIKPLSLRLRSTPPPADQRPSPPPPRDPAPAVRCSVIQRAPQSQLPTSRAGFLLPPLDQLGPEQQEPIDYHVPKRRSPSYDSDEELNARRLERARQVREARRRSTILAARVLLAQSQRLNPRLVRSLPGILAAAAGHGRNSSSSSGAAGQGFQSSGFGSQNSGSGSSSGNQNAGSGAGSPGSGAGGGGGMGGGRDGRGNYGPNSPPTGALPPFYESLKSGQQSTASNNTGQSPGANHSHFNANPANFLQNAAAAAYIMSAGSGGGGCTGNGGGGASGPGGGPSANSGGGGGGGGGNGYINCGGVGGPNNSLDGNNLLNFASVSNYNESNSKFHNHHHHHQHNNNNNNNGGQTSMMGHPFYGGNPSAYGIILKDEPDIEYDEAKIDIGTFAQNIIQATMGSSGQFNASAYEDAIMSDLASSGQCPNGAVDPLQFTATLMLSSQTDHLLEQLSDAVDLSSFLQRSCVDDEESTSPRQDFELVSTPSLTPDSVTPVEQHNTNTTQLDVLHENLLTQLTHNIVRGGSNQQQQHHQQHGVQQQQQQQHSVQQQQQHNVQQQHGVQQQHVQQQPPPSYQHATRGLMMQQQPQHGGYQQQAAIMSQQQQQLLSQQQQQSHHQQQQQQQHAAAYQQHNIYAQQQQQQQQQHHQQQQQQQHHHFHHQQQQQPQPQSHHSHHHGHGHDNSNMSLPSPTAAAAAAAAAAAAAAAAAAHLQRPMSSSSSSGGTNSSNSSGGSSNSPLLDANAAAAAAAALLDTKPLIQSLGLPPDLQLEFVNGGHGIKNPLAVENAHGGHHRIRNIDCIDDLSKHGHHSQHQQQQGSPQQQNMQQSVQQQSVQQQQSLQQQQQQQHHQHHSNSSASSNASSHGSAEALCMGSSGGANEDSSSGNNKFVCRVCMKTFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLESHCQKVHSVQHQYAYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHPFSPALLKFYDKRHFKFTNSQFANNLLGQLPMPVHN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :::: . :. :. * . . . . : * :* * * **:*.**:***. :*:** *****:*:****** *****:**::*. * *:********:* *:*. .***::** *::***:** * : * :. ", "identical_positions": 62, "similar_positions": 42, "identity": "4.57%" }, { "cls_id": "homologset.agr.FB:FBgn0003041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUD0-1", "uniprot_id": "D3ZUD0_RAT", "id": "D3ZUD0-1", "name": "Protein ECT2", "aln": "MADDSVLPSPTEITSLADTSVFDSKVTETSKENLCMVSTSNVDEEMPQVEARVVVVQEAGKQEELLKALKTVKIMEVPVIKIKESCPGKSDEKLIKSIINMEIKVPCVKMDSMEEFGSLDSPEFENIFVVTDFQTSVFNDLYKADCRIVGPPVILNCAQMGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMRPGWIYEAWERRNEQCFCAADDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGTYLPVGDERCTHLIVDEN------------------------------------------------------------------------------TVKELPFEPSKKLFVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRR------------------------------------LKESLAQLSRETDLSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPDSSIHYGETPKSCAKSSRS-----------------------------------------------------------------------------------------------------------------------------------------STPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYSKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLIQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVTDPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRMALSSSH-SSEGRSPPSSGKLAVSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07139-1", "uniprot_id": "ECT2_MOUSE", "id": "Q07139-1", "name": "Protein ECT2", "aln": "MADDSVLPSPSEITSLADSSVFDSKVAEMSKENLCLASTSNVDEEMPQVEARVIMVQDAGKQEELLKALKTIKIMEVPVIKIKESCPGKSEEKLIKSIINMEMKVPCVKMDSMEEFESLDSPEFENIFVVTDFQNSVFNDLYKADCRIVGPPVILNCAQRGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQCFCAAVDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGSYLPVGDERCTHLIVEEN------------------------------------------------------------------------------TVKDLPFEPSKKLFVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRR------------------------------------LKETLAQLSRETDLSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPESSIHYGETPKSCAKSSRS-----------------------------------------------------------------------------------------------------------------------------------------STPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYAKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVADPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRMALSSSH-SSEGRSPPSSGKLAVSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8V3-1", "uniprot_id": "ECT2_HUMAN", "id": "Q9H8V3-1", "name": "Protein ECT2", "aln": "MAENSVLTSTTGRTSLADSSIFDSKVTEISKENLLIGSTSYVEEEMPQIETRVILVQEAGKQEELIKALKTIKIMEVPVIKIKESCPGKSDEKLIKSVINMDIKVGFVKMESVEEFEGLDSPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLPFSCRPLYCTSMMNLVLCFTGFRKKEELVRLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEMQGGKYLPLGDERCTHLVVEEN------------------------------------------------------------------------------IVKDLPFEPSKKLYVVKQEWFWG-----------------------------------------------------------------------------------------------------------------SIQMDARAGETMYLYEKANTPELKKSVSMLSLNTPNSNRKRRR------------------------------------LKETLAQLSRETDVSPFPPRKR------------------------------------------------------------------------------------------PSAEHSLSIGSLLDISNTPESSINYGDTPKSCTKSSKS-----------------------------------------------------------------------------------------------------------------------------------------STPVPSKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLKYSKDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHGQTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPKENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDS-TLSRASRAIKKTSKKVTRAFSFSKTP---KRALRRALMTSHGSVEGRSPSSNDKHVMSRLSSTSSLAGIP----------SPSLVSLPSFFERRSHTLSRSTTHLI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQ97-1", "uniprot_id": "Q8IQ97_DROME", "id": "Q8IQ97-1", "name": "", "aln": "------------------------------MEMETIEEQSKCEMSITTLPTRICLVGGVGQDADTLQAAESFGLPIVTSDTGLDILG--------------------------------ESSDWRTFYVLDDFEGASFEAIHKQKECILGPPALKYAAEMKQTLGQNSRPIYNYAMRGVVTCFTGIRKKDELTKLVNLIHSMGGCIKKDLNTKTTHLICNHSGGEKYQYAKTFRLTVVRPAWVFAAWADRNSLEFDATQENFTKTHRLKAFEGQKICFFGFPVEEHQHMVDVLLENGGVCAELDDPECSHVVMPNTGAVFTSTSTSTDTNPSTLINPPESQVPGSSSASQAGEEEQRKAEHLEQAEIKKMEYSHAETDNGMSLDIDQEQKENQGIEDEDDIHFDERLFVEAADIINHGEDQLPESDEEDLEEEQKPKVEEVLKEQEVEEDVQASTPKTSKIRTSLKAATPLSSPEMDGIALDFESTTQNISPILKAIDECDLETDDLPPSENDLKRKRESFDNVSLMSVDSFALPASTKKPKLIRTGSISRTLRRSVSFVAEPLMKTLRPRRSSVADASSFVGSEAADNSICSLASSINLTLNDSIRKPVKEKLRSFCGRITRSSSRRHDRGVDGTPECTTLLDSGFKTPKAPKLRSTATPKTAKRLFGPVSGVVSALTLTNPSTPTPNPNPNTNCTATLDVNDTSIHTFAFCAAAVTPAMPPSSSSSSSSPILSTSIAVHSSVQVIKSPEESTTRRNSPAPIEEPMAMVVDEHTTLTKPEPKNNHTHILKSDWFWYTIQNGYANEMDYLFGDYLDSITNTPNTDRRDSLPISFNKRKRKRFSQRIQLEGTPLGSGKRRSSVSDAGLLSVSNSLFDCTTSPDKLESDKLLHAEPEASDATPAKKSMRFNHFMDFYTTESNYVGILDTILNLFKNKLEELAETNDPLLNKSEIKTIFGNFLPIHEVHQSMLEHLRKLHANWREDCLIGDIIIQHRDELIKAYPPYVNFFEQMKEQLQYCDREYPRFHAFLKINQTKPECGRQGLQDLMIRPVQRLPSISLLLNDILKHTTSGNADHGRLEEALKAIKQVTLHINEDKRRTESRMAIFDIFNDIEGCPAHLVSSNRSFILKCEVNELSDSLSGRGDSLVLYLFSDSIELCKRRSKGFNTAKSPS----TAKTHKHLKLISLNTIRLVIDISDSP---RAFGLLLR---GDKEKLYTFTISDEETDKSVYVKKLCNQIAAHTCRTDADKLLICRTSQELEVDISDVNVSTLSKAFKLAAKTRLKVGRAFSFNKTPNKLKRAVSTMMTSPFGSTNSLTPAS--QLAQMRLASCTNINEVDDEDCASMRSSSPSTQSEMLVVPPLSVQPTRKNKAVVGRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 289, "similar_positions": 320, "identity": "20.87%" }, { "cls_id": "homologset.agr.FB:FBgn0003042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT11-1", "uniprot_id": "E9PT11_RAT", "id": "E9PT11-1", "name": "", "aln": "MELSAVG---------------ERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQKERERELYGPKKRGPKPKTFLLKARAQAEALRISDVHFS--------------VKPSASASSP---KLHSSAAVHRLKKDIRRCHRMSRRPLPRPDPQGGNPG---LRPPISPFSETVRIINR-------KVKPREPKRNRIILNLKVIDKGPGGGSTAQG--------TGALARPKVPSRNRVIGKSKKFSESMLR-----------TQIRHMKFGTF-ALYKPPPAPLVPSTAGK----ADVASSGPGLLLATPA-------AAPFDAHSSSSSGCP------------------------SPTLQSSDP--------------DDAPPKLLPET--ISRSASNWRESE----VLDLSIPPEAAATGQRVPPDVTAAAGQALHTVLEATGTGSSEPEAG---DWRPEMSP-------------------------------------------------CSNVVVTDVTSNLLTVTIKEFCSPEDFEKVAAGVAGATGGGGGTGPSK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBY5-1", "uniprot_id": "CBX6_MOUSE", "id": "Q9DBY5-1", "name": "Chromobox protein homolog 6", "aln": "MELSAVG---------------ERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQKERERELYGPKKRGPKPKTFLLKARAQAEALRISDVHFS--------------VKPSASASSP---KLHSSAAVHRLKKDIRRCHRMSRRPLPRPDPQGGSPG---LRPPISPFSETVRIINR-------KVKPREPKRNRIILNLKVIDKGPGGGSTAQG--------TGALARPKVPSRNRVIGKSKKFSESMLR-----------TQIRHMKFGTF-ALYKPPPAPLAPSTAGK----ADVASSGPGLLLATPA-------AAPFDAHSSSSSGCP------------------------SPTLQSSDP--------------DDAPPKLLPET--LSRSVPNWRESE----VLDLSIPPEAAATGQRVPPDVTGAADQALHTALEPTGAGSSEPEAG---DWRPEMSP-------------------------------------------------CSNVVVTDVTSNLLTVTIKEFCSPEDFEKVAAGVAGATGGGGGTGPSK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95503-1", "uniprot_id": "CBX6_HUMAN", "id": "O95503-1", "name": "Chromobox protein homolog 6", "aln": "MELSAVG---------------ERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQKERERELYGPKKRGPKPKTFLLKARAQAEALRISDVHFS--------------VKPSASASSP---KLHSSAAVHRLKKDIRRCHRMSRRPLPRPDPQGGSPG---LRPPISPFSETVRIINR-------KVKPREPKRNRIILNLKVIDKGAGGGGAGQG--------AGALARPKVPSRNRVIGKSKKFSESVLR-----------TQIRHMKFGAF-ALYKPPPAPLVAPSPGK----AEASAPGPGLLLAAP--------AAPYDARSSGSSGCP------------------------SPTPQSSDP--------------DDTPPKLLPET--VSPSAPSWREPE----VLDLSLPPESAATSKRAPPEVTAAAGPAPPTAPEPAGA-SSEPEAG---DWRPEMSP-------------------------------------------------CSNVVVTDVTSNLLTVTIKEFCNPEDFEKVAAGVAGAAGGGGSIGASK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WBY5-1", "uniprot_id": "X1WBY5_DANRE", "id": "X1WBY5-1", "name": "", "aln": "MELSAAG---------------DRVFAAEAILKRRVRKGRMEYLVKWKGWAIKYSTWEPEENILDERLVAAFEQKEREQEMYGPKKRGPKPKTLLLKSRAQAESPRVPEFKHSRPQPHSKPPPPPPPAAPSYTPTAPSNAKLQSGTAQPKLKKDIHRCHRMARRPLPRQDHTVGPSGPFSSRPTVSAFSETVRILNR-------KVKPREVKKGRVILNLKVLDKAENTAVANNKRTHVPSTQQSHFGRQKIPSRNRVIGKNRRFGEVSYRGIQ--------PPIRGSGFPVFGKLFDSHSLKNAESGESRNSMTNNLSSSQSSKLLDVSKGQNRNEEPPPSNSSSEVSDGEPPSPRQTQSQHSS---LQPKASSTKSPSTKAPDPTLHKLGTQPVASKNKDSASSALPSSPMFSSSSSASTSSEDNEHILDLSVPHEMDRRLRRRHP-FSGRHPLKVPEVPVSEEP-SEEEEDL---DWRPDMTSR------------------------------------------------CANVVVTDITANLLTVTIKEFCHPPSASSPPCYSKNVSTQNDTQQPKQNPNKT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9HC52-1", "uniprot_id": "CBX8_HUMAN", "id": "Q9HC52-1", "name": "Chromobox protein homolog 8", "aln": "MELSAVG---------------ERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDS-----------------ARGIRIP-----YPGRSPQDLASTSRAREGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKK-------------RGPKPRKELPDPSQRPLGEPSAG---------------------LGEYLKGRKLDDTPSGAGK------FPAGHSVIQLARRQ------------DSDLVQCGVT------------------------SPSSAEATG----------KLAVDTFPARVIKHRAAFLEAKGQGALDPN---GTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEE---SWSPSLTN-------------------------------------------------LEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXV1-1", "uniprot_id": "CBX8_MOUSE", "id": "Q9QXV1-1", "name": "Chromobox protein homolog 8", "aln": "MELSAVG---------------ERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDS-----------------TRGIRIP-----YPGRSPQDLASTSRAREGLRNTGLPPPGSST---STCRADPPRDRDRERDR------------------------GTSRVDDKPSSPGDSSKK-------------RGPKPRKEPLDPSQRPLGEPSAG---------------------LGEYLKGRKLDETSSGTGK------FPAGHSVIQLARRQ------------DSDLVQYGVT------------------------SPSSAEASS----------KLAVDTFPARVIKHRAAFLEAKGQGALDPG---GARVRHSSGTPASVGSLYRDMGAQGGRPSLIARIPVARILGDPEEE---SWSPSLTN-------------------------------------------------LEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95931-1", "uniprot_id": "CBX7_HUMAN", "id": "O95931-1", "name": "Chromobox protein homolog 7", "aln": "MELSAIG---------------EQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGK--------------EKLCFSLTCP-------------LGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKF------PPRGPNLESHSHRRELFLQEPPAPDVLQAAG--------------EWEPAAQ----PPEEEADADLAE----------------------------------------------GPP-------------------------------------------------------------------------------------------------------------------------------------------------------------PWTPALPS--------------------------------------------------SEVTVTDITANSITVTFREAQAAEGFFRDRSGKF--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60889-1", "uniprot_id": "CBX7_RAT", "id": "P60889-1", "name": "Chromobox protein homolog 7", "aln": "MELSAIG---------------EQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEEKDRASGYRKRGPKPKRLLLQ------------------------------------------------------------------------------------------------------------------------------ESAAPDVLQATG--------------DWEPVEQ----PPEEEAEADLTN----------------------------------------------GPP-------------------------------------------------------------------------------------------------------------------------------------------------------------PWTPMLPS--------------------------------------------------SEVTVTDITANSVTVTFREAQAAEGFFRDRSGKL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDS3-1", "uniprot_id": "CBX7_MOUSE", "id": "Q8VDS3-1", "name": "Chromobox protein homolog 7", "aln": "MELSAIG---------------EQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPRRLLLQ------------------------------------------------------------------------------------------------------------------------------ESAAPDVVQTPG--------------DWEPMEQ----APEEEAEADLTN----------------------------------------------GPP-------------------------------------------------------------------------------------------------------------------------------------------------------------PWTPTLPS--------------------------------------------------SEVTVTDITANSVTVTFREAQAAEGFFRDRNEKL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N5K1-1", "uniprot_id": "A0A8M1N5K1_DANRE", "id": "A0A8M1N5K1-1", "name": "", "aln": "MELSSIG---------------EQVFAVESITKKRIRKGNVEYLLKWQGWSPKYSTWEPEDNILDPRLVLAFEEKAEKDRALAYKKKGLRPRQVILRNIYPMDLRSAHKVPDK--------------PSPRIRLSLTR----SMSTEVDQNGRRYRDSVVYRRLKNRYKNRQCRSRLFEGIKPSKQTMRHPLPAKDCT------ENAWNEDEQKRKVKKMRKDEENTTQVHQDIP--------------SGQEMSEGYNSSAEQESEITIKED-----------------ENCSSIFDQEEKPSEDTGTAI-------GAPESSTITDTEK-----------NEPVTNTAGDE------------------------DCVWVSHDT---------------TNTDQSLHKCTKSGAEEGVFDRVQNRPSVIEVRLSARCGQEEVRESAEVGSSEAKDKEGIDAEVTAEFQVPIDQLQTPVTTAVHP--------------------------------------------------GKVIVTQVTINSLTVTFKEAMTAEGFFSECGLEV--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6ACN6-1", "uniprot_id": "A0A8I6ACN6_RAT", "id": "A0A8I6ACN6-1", "name": "", "aln": "MELPAVG---------------EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQD-------------SSADNRAKLELGTQGKGQGHQYELNSKKHHQYQPHGKERSGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGSHKEAPSPTCPDLGAKSHPPDKWAHGAAAKGYLGAVKPLGGGAGAPGKGSEKGPPNGLTPAPKEAVAGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEAAESEARSPSHKKRAAEERHPQADRTFKKAAGASEEKKAEVPCKRREEEALVSGDPQPQDLGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARSSHPPAHH------HHHHHHHHHHHTVGLNLSHARKRCLSETHGEREPCKKRLTARSISTPTCLGGSPVSEHPANVSPTAASLPQPEVILLDSDLDEPIDLRCVKMRSDAGEPPSTLQVKPEAP-----AVAAVVAPATAAEKPPAEAQEEPAEPLSEFKPFFGNIIITDVTANCLTVTFKEYVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55187-1", "uniprot_id": "CBX4_MOUSE", "id": "O55187-1", "name": "E3 SUMO-protein ligase CBX4", "aln": "MELPAVG---------------EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQD-------------SSADNRAKLELGTQGKGQGHQYELNSKKHHQYQPHSKERSGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGTKSHPPDKWAHGAAAKGYLGAVKPLGGGAGAPGKGSEKGPPNGMTPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEAAEGEARSPSHKKRAAEERHPQGDRTFKKAAGASEEKKAEVPCKRREEEALVSGDAQPQDLGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARSSHPPAHH------HHHHHHHHHHHTVGLNLSHARKRCLSETHGEREPCKKRLTARSISTPTCLGGSPVSEHPANVSPTAASLPQPEVILLDSDLDEPIDLRCVKMRSDAGEPPSTLQVKPEAP-----AVAAVVAPAPASEKPPAEAQEEPVEPLSEFKPFFGNIIITDVTANCLTVTFKEYVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00257-1", "uniprot_id": "CBX4_HUMAN", "id": "O00257-1", "name": "E3 SUMO-protein ligase CBX4", "aln": "MELPAVG---------------EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQD-------------SSTDNRAKLDLGAQGKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADERHPPADRTFKKAAGA-EEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPP-AAALPQPEVILLDSDLDEPIDLRCVKTRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26017-1", "uniprot_id": "PC_DROME", "id": "P26017-1", "name": "Polycomb group protein Pc", "aln": "MTGRGKGSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSS--GTPSKRGIKKKEKEPDPEPESEEDEYTFTEND---------------VDTHQATTS-------SATHDKESKKEKKHHHHHHHHHHIKSERNSGRRSESPLTHHHHHHHHESKRQR--------IDHSSSSNSSFTHNSFVPEPDSNSSSSEDQ------------PLIGTKRKAEVLKESGKIGVTIKTSPD-------------------GPTIKPQPTQQVTPSQQQ-----PFQDQQQAEKIASEA----------------------------------------------------------------------ATQLKSEQQATPLATEAINTTPAESGAEEEEVANEEGNQQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALPPRFWLPAKCN------------------------------------------------ISNRVVITDVTVNLETVTIRECKTERGFFRERDMKGDSSPVA--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : *:*.* : ::*::** :** :**:** :*.***** :*** **: ::: . *:* : : : . . : : : : : * . ", "identical_positions": 28, "similar_positions": 32, "identity": "4.75%" }, { "cls_id": "homologset.agr.FB:FBgn0003044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFS0-1", "uniprot_id": "A0ABK0LFS0_RAT", "id": "A0ABK0LFS0-1", "name": "Metal-response element-binding transcription factor 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDSTGAGNSLVHKRSPSRRNQKTSASLNKLSLQDG-------------------------------HKAKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFITFEDSSKSWVLWKDIQTGATGS-------------------GEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINDNWDRLHPGELA-DTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAE-KEPEG--------------------------------------TSHEFKIKGRKASKPTSDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPP--------------------------LGKESVSENPALDLPCSIGRTEGVAHSSNTSDVDLTG-------ASSAKETTSSSIPRHYGL------------------------SDSRKRTRTGRSWPASIPHLRRRRGRLPRRALHTQNSEV-------------------------------------VKDDEGKEDYQFEELNTEILNNLADQELQLNHLKNSITS--YFGAAGRIACGEKYRVLARRVTLDGKHLQKMAFLVTLSPKEAENFLSCFWFLVDQHLREKEKSTEVVNPGSCWNRQTQKKRTKPCCCLRSWHGQPRGSPRADTEGFRKVTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02395-1", "uniprot_id": "MTF2_MOUSE", "id": "Q02395-1", "name": "Metal-response element-binding transcription factor 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDSTGAGNSLVHKRSPLRRNQKTSASLNKLSLQDG-------------------------------HKAKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGS-------------------GEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELA-DTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAE-KEPEG--------------------------------------TSHEFKIKGRKASKPTSDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAELP--------------------------LDKESVSENPTLDLPCSIGRTEGIAHSSNTSDVDLTG-------ASSANETTSASISRHCGL------------------------SDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEV-------------------------------------VKDDEGKEDYQFEELNTEILNNLADQELQLNHLKNSITS--YFGAAGRIACGEKYRVLARRVTLDG----KVQYLVEWEGATAS--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y483-1", "uniprot_id": "MTF2_HUMAN", "id": "Q9Y483-1", "name": "Metal-response element-binding transcription factor 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDG-------------------------------HKAKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGS-------------------GEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELA-DTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAE-KEPEG--------------------------------------TSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPL--------------------------LDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTG-------ASSAKETTSSSISRHYGL------------------------SDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEI-------------------------------------VKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITS--YFGAAGRIACGEKYRVLARRVTLDG----KVQYLVEWEGATAS--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M1Y4-1", "uniprot_id": "F1M1Y4_RAT", "id": "F1M1Y4-1", "name": "PHD finger protein 19", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METQALEPGTQEAFGATS--PNKGAPSKTKKNFKD-------------------------------------LMSKVTEGQFVLCRWTDGLYYLGKIKRVSSPKQSCLVTFEDNSKYWVLWKDIQHAGVPG-------------------EEPKCDVCMGKTSGPMNEILICGKCGLGYHQQCHIPIAVDANWPLLTHWFCRRCIFALAVRKGGALKKGAIAKTLQAVKMVLSYQPEELDWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLSEPMVFGDRFYLFFCSVCNQGPEYIERLPLRWVDIVHLALYNLGVQSKKRYFDFE-EILAFVNHHWELLQLGKLT-STPVTERGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRVRVPPAPPGKLLPDRAQMPSD--------------------------------------KGTFELLRKRGKSKPGLLPQESQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWST--------------------------DHHLASIFDFTLDEIQSLKSGS--SGQTFFSDVDSTD-------AASTSGSASTSLS-----------------------------QDSRWTVGSRKRKLAAKAYRPLRAKHRAAEPDGRCASDS-------------------------------------SAEGAPGPEQQDEGIDSHTFESISGDDSSLSHLKSSITN--YFGAAGRLACGEKYQVLARRVTPEG----KVQYLLEWEGTTPY--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXG9-1", "uniprot_id": "PHF19_MOUSE", "id": "Q9CXG9-1", "name": "PHD finger protein 19", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METQALEPGTLEAFGATS--PNKGGLSKTKKNFKD-------------------------------------LMSKVTEGQFVLCRWTDGLYYLGKIKRVSSPKQSCLVTFEDNSKYWVLWKDIQHAGVPG-------------------EEPKCDVCMGKTSGPMNEILICGKCGLGYHQQCHIPIAVDANWPLLTHWFCRRCIFALAVRKGGALKKGAIAKTLQAVKMVLSYQPEELDWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLSEPMVFGDRFYLFFCSVCNQGPEYIERLPLRWVDIVHLALYNLGVQSKKRYFDFE-EILAFVNHHWELLQLGKLT-STPMTERGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPAPPGKLLPDRALMPSD--------------------------------------KGTSELLRKKGKSKPGLLPQEPQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWST--------------------------DHHLASIFDFTLDEIQSLKSGS--SGQTFFSDVDSTD-------AASTSGSASTSLS-----------------------------YDSRWTVGSRKRKLTAKVHRPLRAKQRAAELEGRCASDS-------------------------------------NAEGAVGPEQPDEGIDSHTLESISGDDSSLSHLKSSITN--YFGAAGRLACGEKYRVLARRVTPEG----KVQYLLEWEGTTPY--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T6S3-1", "uniprot_id": "PHF19_HUMAN", "id": "Q5T6S3-1", "name": "PHD finger protein 19", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENRALDPGTRDSYGATSHLPNKGALAKVKNNFKD-------------------------------------LMSKLTEGQYVLCRWTDGLYYLGKIKRVSSSKQSCLVTFEDNSKYWVLWKDIQHAGVPG-------------------EEPKCNICLGKTSGPLNEILICGKCGLGYHQQCHIPIAGSADQPLLTPWFCRRCIFALAVRKGGALKKGAIARTLQAVKMVLSYQPEELEWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLNEPMMFGDRFYLFFCSVCNQGPEYIERLPLRWVDVVHLALYNLGVQSKKKYFDFE-EILAFVNHHWELLQLGKLT-STPVTDRGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPGKLLPDKGLLPNE--------------------------------------NSASSELRKRGKSKPGLLPHEFQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWST--------------------------NHHLASIFDFTLDEIQSLKSAS--SGQTFFSDVDSTD-------AASTSGSASTSLS-----------------------------YDSRWTVGSRKRKLAAKAYMPLRAKRWAAELDGRCPSDS-------------------------------------SAEGASVPERPDEGIDSHTFESISEDDSSLSHLKSSITN--YFGAAGRLACGEKYQVLARRVTPEG----KVQYLVEWEGTTPY--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE79-1", "uniprot_id": "A0A8M2BE79_DANRE", "id": "A0A8M2BE79-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLESACRDGYLTA-GSES-LEPKHLHPNIEKSICD-------------------------------------QETSLTVGQYVLCCWSDGLYYLGKIQRVSTSKQSCFVSFEDNSKFWVLWKDIQHAGIPG-------------------EEPKCSVCSDMSLDPGNEILICGKCGVGFHQLCHLPTVESSADP--SPWFCRRCIFALAVRKGGALKKGQLAKDLQAMKQVLTYNPEELEWDSLHRTNHQQCYCYCGGPGQWYLKMLQCFRCEQWFHEACTQCLQDSMMFGDRFYLFICAVCNKGVEYIKRLALRWVDVVHLALYNLGVQSKKKYFELE-EIVAFINNNWDRFQMGKLS-NTPLPERGQLILDALNNYKSKFLCGKEIKKRKCIFRLRTRVPPNPPSKLYPEKAQKSDA--------------------------------------HRG----RKKAVSRS---SNSDPAEKR---RKKRAKWLLEDAIPNNDLTSSWST--------------------------NHHMANIFDFTLDELQSLKSTS--SGQTFSLDQDSTD-------AASTSGSATTSVS-----------------------------YDFRKNVGSRKRKLPTSNYNLLATKRELVE---REPSPI-------------------------------------NMPGEERNVLMENGIDSHTFESISEDDSSLLHLKSSITS--YFGAAGRLTCGEKYQVLARRITPEG----KVQYLVEWEGTTPY--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0KW73-1", "uniprot_id": "A0ABK0KW73_RAT", "id": "A0ABK0KW73-1", "name": "PHD finger protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQLPRLSRLGAPSLWDPASPAPTSG------------------------------------------PRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPG-------------------EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGSSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELS-DTPKGERSSKLLSALNSHKDRFISGREIKKRKCLFGLHARTP--PPVELLTGDGSPTRSLVQGGWGKFSRICLEGTCTENGGLGCLGGGWGDKEASYSFPSGQGPGGGVSRPLGKRRKSEPEPLRRRQKGKVEELGPPTAAHSRHGSQEQR---------------------------ALQASESPPPPSPNQSYQGSS--GYNFRPTDARCLP-------SSPIRMFASFHPS-------------------------------ASTAGTSGDSEPPDRSPLELHIG-FPTDIPKSSPHSV-------------------------------------TASSSSVPAL------TPGLSRHSLPPSPLCRSLSPGTGGGVRGGVSYLSRGDPVRVLARRVRPDG----SVQYLVEWGGGGIF--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1B8-1", "uniprot_id": "PHF1_MOUSE", "id": "Q9Z1B8-1", "name": "PHD finger protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQLPRLSRLGAPSLWDPASPAPTSG------------------------------------------PRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPG-------------------EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGASWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELS-DTPKGERSSQLLSALNSHKDRFISGREIKKRKCLFGLHARTP--PPVELLTGDGAPT----------------------------------------SFPSGQGPGGGVSRPLGKRWRSEPEPLRRRQKGKVEELGPPTAAHSRHGSREQR---------------------------ALQASVSPPPPSPNQSYEGSS--GYNFRPTDARCLP-------SSPIRMFASFHPS-------------------------------ASTAGTSGDSEPPDRSPLGLHIG-FPTDTPKSSPHSV-------------------------------------TASSSSVPAL------TPGFSRHS-PPSPLCRSLSPGTGGGVRGGVSYLSRGDPVRVLARRVRPDG----SVQYLVEWGGGGIF--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43189-1", "uniprot_id": "PHF1_HUMAN", "id": "O43189-1", "name": "PHD finger protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQPPRLSRSGASSLWDPASPAPTSG------------------------------------------PRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPG-------------------EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGTSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELS-DTPKGERSSRLLSALNSHKDRFISGREIKKRKCLFGLHARMP--PPVEPPTGDGALT----------------------------------------SFPSGQGPGGGVSRPLGKRRRPEPEPLRRRQKGKVEELGPPSAVRNQPEPQEQRERAH--------------------LQRALQASVSPPSPSPNQSYQGSS--GYNFRPTDARCLP-------SSPIRMFASFHPS-------------------------------ASTAGTSGDSGPPDRSPLELHIG-FPTDIPKSAPHSM-------------------------------------TASSSSVSSP------SPGLPRRSAPPSPLCRSLSPGTGGGVRGGVGYLSRGDPVRVLARRVRPDG----SVQYLVEWGGGGIF--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24459-1", "uniprot_id": "PCL_DROME", "id": "Q24459-1", "name": "Polycomb protein Pcl", "aln": "MMNNHFHLQHDHPPQNVAHPFMQQPSTAVPSAPPATYGYLAQPAGQQPQWMTTTYQILPPSVGPATVAKRYYATTGPQTTHPTHPSTIQITNSFAQQSTPPKQQAATSCSPFKANNIRIISTAPSVYSLNKPPQEAHSTYAPVQSYYLPSGGGQTAGQINLLAASGTGKQLQPPPLVPVTNSTSPPSTVVLDRINICINNHYTETPTSLSSSLTTAQQPSPIIPAIQHKAILPLIDSSTADSSSCSSSSVSSSSYSGTATTSAAVVIVDEPDSTTTTPQTPPTTPEAMSSPGKSSPSPPLLATQSLLKGVNSMKPSFKTVEAAPPTPPTPPSPPPPPPAPPVAAPSPAVTYALQEDVFIKCNDGRFYLGTIIDQTS--DQYLIRFDDQSEQWCEPDKLRKLGGGSSITAGGGGASTTESTNTSPSGPMCVACK--RSDIEDVVEICERCGRGYHRGCTVEIVTG-----SGIWSCKRCAKPMKMQQPVSHK----ITKPAGICRQLPYHADKLSWDEKHRVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNFKKKLLRGDMFFVFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQHQKYHHLLNDIWPFILEQRHQLPICEKWRTLPETALMERLKQTLKDYSDRFVCGREFKRAPAFYALRHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMPEEPDEGANELPKRVPKDVYEFN----TDEDDPVETSEDEIPIKQIIEKAKKQAAQKADKHDELPLKPDLADDNANDGDPGKLPAPIPPLLDANSSRKRKAFRLSKRYDNSRNHCDLSSDENSSSSRGTSSLDLIIPPPVNFLGRNNPFLMATPKKASQGRSISVGTGVGVNGIINSIFKLKGTSKEQPRMVRTIKRRLSAKDITIGPNQEVRRRRTRRLTTAIEVISTTTINPIPSHYLPIYAKDLQPPAPPMGKPTHGRLLRQRPQKQSPSQSRRNSTSSTATSSSSNGIGAPGHSMLDLKQSVNK-YFGGAMNRIDAGEPFAIRAKRRMGNG----QVQYLVEWGGDTATTAIGLLGN------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: .** ***.* : :: *:*.*: ..: . . * * : : * :* .:*: * * *::* . :: : * : *.* *.** * * :* ***** **.: .**** * :*** * * :.. :: ** *: * * ** * * :.*: :.***: *: **:* :::*.. :: .: .: . : : * : .:*:.:. *:.*:*:*: :: *: * * . . . . . * ::. . . . . : . : .. . *. . : *: : *:* :* .: :*: ", "identical_positions": 79, "similar_positions": 108, "identity": "7.02%" }, { "cls_id": "homologset.agr.FB:FBgn0003048", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSU6-1", "uniprot_id": "PCX1_RAT", "id": "E9PSU6-1", "name": "Pecanex-like protein 1", "aln": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMIIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRSAN----------------------------------------------------------------------------------------EFTDQRAKAEQGNCSTRRKDSNGPSDPGGGIEMSEFIR-EATPPVGCSSRNSYAGLD-------------------PSNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSS-------------LCKEGSEEQDLATDRKLFRLVSNDSFVSIQPSLSSCGQDLPRDFSDKVSLPSHSQHHRVDQSLCSACDTEVAS----LVPLHSHSYRKEH-RPRGVPRTSSSA-VAFPDASLSGLPLYQQQQRRGLDPVTELDSSKPHSGTRESLVGQSCPLAQS--------------------------QPAADRRKSYSQPPTK----------CGKSRA--------LNAEKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHDESPKVGDKSARKEGC-AESAEERCHGATDRRTSSDKTALEGSTPAGPPEAPDAQASEEKPDQVAPSSSASEDANKNPHAN-EFTV--PGDRPPE---------QSAESKEEQGEKPSLSTDSKVCKDDGGKQKEGD--VRPKSSSLIHRTTS------AHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGTKPHSAIFCHDE-DSSDQ--------------------SDLSRAPSVHSAHHFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRGTDSDHTHRAHPGPEGTAKKRASRRTSSTHSAKTRARVLSLDSGTVACLNDSNRLLAPDSIKPLTTS---------------KSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAATGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGPPLSLQD--GQQGQQSTAQVKVQ-SRPPSQAAVLSASASLLVRKGS------------------------------------------------VHLDASHDHASAVGGSSLHDELGKFSSTLYETGGCDMSLVNFEPAARR---------------------------ASN-ICDTDSHVSSSTSV--RFYPHDMLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLAAT--------------YGPTEEAAQKVKHYYRF---WILPQLWIGINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSP--RHGHNRIIAYSRPVYFCLCCGLIWLLDYGSR---NLSTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSVVAVALLYGLCYGALRDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLIQSKIFPKTDE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGFVGLVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLFVEKNVIYPLIVLNELSSSADTIAS-PKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFVQAVVSALFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIETGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVD-PTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------AKP------LDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRDFIVSTWHRLRKGCGAGCNSGG-NIEDS--------------------DTGGGTSCPANSATTASDPHNSVPQGSTGHPG-----------------QGAGSGLHPPTTSYPPTLG------TSHSAHSVQSSLVRQSPARASMASQSS-YCYG------------SRHSSLRMSTTGFVPCRRS--STSQISLRNLPSSIQSRLSMVNQMEAASQGGMGCVQHGLPSSSSSSQSIPACK--HHTLVAFLGAEGSQSGATEAQPG---------NTSSPATISHARK---------GEVVYRVQIVDLSQILEGINV------SKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVVHRWVPCSRDPSTRSHIDKTVLLVQIDDKYVTVIETGVLELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYC1-1", "uniprot_id": "PCX1_MOUSE", "id": "Q9QYC1-1", "name": "Pecanex-like protein 1", "aln": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMIIVAVYCPVVAAVFIILKMVNYRLHRALDAGEIVDRSAK----------------------------------------------------------------------------------------EFTDQRAKAEQGNCSTRRKDSNGPSDPGGGIEMSEFIR-EATPPVGCSSRNSYAGLD-------------------PSNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSS-------------LCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHRVDQSLCSACDTEVAS----LVPLHSHSYRKEH-RPRGVPRTSSSA-VAFPDASLSGLPLYQQQQRRGLDPVTELDSSKPHSGTRESSAGKSCPPAQS--------------------------QPAADRRKSSSQPPTK----------CGKSRA--------LNAEKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGDKSARKRECGADSVEERSHRADDRRTSSDKTAPEGNTPAGPPEAPDAQASEEMADQAAPSSSASEDANKNPHAN-EFTV--PGDRPPE---------QSAESKEEQSEKPSLATDSRVCKDDGGKQKEGD--VRPKSSSLIHRTTS------AHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGTKPHSAVFGHDE-DSSDQ--------------------SDLSRAPSIHSAHQFSSDSSSSATSHSCQSPEGKYGALKTKHGHRDRGTDSDHTHRAHPGPEGTTKKRASRRTSSTSSAKTRARVLSLDSGTVACLNDSNRLLAPDSMKPLTTS---------------KSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAATGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQD--GQQGQQSTAQVKVQ-SRPPSQAAVLSASASLLVRKGS------------------------------------------------VHLEASHDHASAVGGSSLHDELGKFSSTLYETGGCDMSLVNFEPAARR---------------------------ASN-ICDTDSHVSSSTSV--RFYPHDMLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLAAT--------------YGPTEEAAQKVKHYYRF---WVLPQLWIGINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSP--RHGHNRIIAYSRPVYFCLCCGLIWLLDYGSR---NLTTSKFKLYGVTFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALRDSWDGQHVPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKADE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVIIGVLYFAIHVSTVFTALQPALKYVLYALVGVVGLVTHYVLPQVRKQLPWHCFSRPLLRTAEHSQYEVRNAATMMWFEKLHVWLLFVEKNIIYPLIVLNELSSSAETIAS-PKKLDTELGALMITIAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFVQAIVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVD-PTFNPNIDEDYDHRLAGISRESFCVIYLSWIEYCSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------AKP------LDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGG-NIEDS--------------------DTGGGTSCPGNSAVTASDPHNNVSQGSTGHPG-----------------QGAGSGLHPPTTSYPPTLG------TSHSAHSVQSSLVRQSPARASMASQSS-YCYS------------SRHSSLRMSTTGFVPCRRS--STSQISLRNLPSSIQSRLSMVNQMEAASQGGMGCVQHGLPSSSSSSQSIPACK--HHTLVAFLGAEGGQGSATEAQPG---------NTSSPANISHARK---------GEVIYRVQIVDLSQILEGINV------SKRKELHWPDEGIRLKAGRNSWKDWSPQEGMEGHVVHRWVPCSRDPSTRSHIDKTVLLVQIDDKYVTIIETGVLELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RV3-1", "uniprot_id": "PCX1_HUMAN", "id": "Q96RV3-1", "name": "Pecanex-like protein 1", "aln": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSTMIIVAVYCPVIAAVFIVLKMVNYRLHRALDAGEVVDRTAN----------------------------------------------------------------------------------------EFTDQRTKAEQGNCSTRRKDSNGPSDPGGGIEMSEFIR-EATPPVGCSSRNSYAGLD-------------------PSNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSS-------------LCKEGSEEQDLAADRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVNLPSHNHHHHVDQSLSSACDTEVAS----LVPLHSHSYRKDH-RPRGVPRTSSSA-VAFPDTSLNDFPLYQQ--RRGLDPVSELESSKPLSGSKESLVENSGLSGEF--------------------------QLAGDLKINTSQPPTK----------SGKSKP--------LKAEKSMDSLRSLSTRSSGSTESYCSGTDRDTNSTVSSYKSEQTSSTHIESILSEHEESPKAGTKSGRKKEC-CAGPEEKNSCASDKRTSSEKIAMEASTNSGVHEAKDPTPSDEMHNQRGLSTSASEEANKNPHAN-EFTS--QGDRPPG---------NTAENKEEKSDKSAVSVDSKVRKDVGGKQKEGD--VRPKSSSVIHRTAS------AHKSGRRRTGKKRASSFDSSRHRDYVCFRGVSGTKPHSAIFCHDE-DSSDQ--------------------SDLSRASSVQSAHQFSSDSSSSTTSHSCQSPEGRYSALKTKHTHKERGTDSEHTHKAHLVPEGTSKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDSNRLMAPESIKPLTTS---------------KSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPNQVAFPEGEEQDAVSGAAQASEEAVSFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQD--GQQGQQSTAQVKVQ-SRPPSQAAVLSASASLLVRNGS------------------------------------------------VHLEASHDNASAVGGSSLHDELGKFSSTLYETGGCDMSLVNFEPAARR---------------------------ASN-ICDTDSHVSSSTSV--RFYPHDVLSLPQIRLNRLLTIDTDLLEQQDIDLSPDLAAT--------------YGPTEEAAQKVKHYYRF---WILPQLWIGINFDRLTLLALFDRNREILENVLAVILAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSP--RHGHNRIIAYSRPVYFCICCGLIWLLDYGSR---NLTATKFKLYGITFTNPLVFISARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFICSIVAVALLYGLCYGALKDSWDGQHIPVLFSIFCGLLVAVSYHLSRQSSDPSVLFSLVQSKIFPKTEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNPEDPLSEVKDPLPEKLRNSVSERLQSDLVVCIVIGVLYFAIHVSTVFTVLQPALKYVLYTLVGFVGFVTHYVLPQVRKQLPWHCFSHPLLKTLEYNQYEVRNAATMMWFEKLHVWLLFVEKNIIYPLIVLNELSSSAETIAS-PKKLNTELGALMITVAGLKLLRSSFSSPTYQYVTVIFTVLFFKFDYEAFSETMLLDLFFMSILFNKLWELLYKLQFVYTYIAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFIQAAVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHIPHMLSFNAAFSQRWLAWEVIVTKYILEGYSITDNSAASMLQVFDLRKVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVD-PTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------AKP------VDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSIRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHEQLKDILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGG-NIEDS--------------------DTGGGTSCTGNNATTANNPHSNVTQGSIGNPG-----------------QGSGTGLHPPVTSYPPTLG------TSHSSHSVQSGLVRQSPARASVASQSS-YCYS------------SRHSSLRMSTTGFVPCRRS--STSQISLRNLPSSIQSRLSMVNQMEPSGQSGLACVQHGLPSSSSSSQSIPACK--HHTLVGFLATEGGQSSATDAQPG---------NTLSPANNSHSRK---------AEVIYRVQIVDPSQILEGINL------SKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BET8-1", "uniprot_id": "A0A8M3BET8_DANRE", "id": "A0A8M3BET8-1", "name": "Pecanex-like protein", "aln": "MGSQTLQILRQGVWASVTGGWYYDPHQNTFVNALHLYLWLLLLCLPFTLYMALPPTMVIVGIYCGVIAGMFVLLKAVNYRLHTALDEGEVVELRAKG--------------------------------------------------------------------------------------SEGRGQGAERQREGTSTRQEDSNGPGDPGGGIEMSDFAR-DETPPVDCSSRNSYVGMD-------------------SSHQITSHG-----ASVTNKRTGVGKAPDDISLSFAQS-------------------CSQDQDLMSDPKMFCLVSNDSFASMQPSTS-----LAQDLYG-------STPHPFSQSLS-SCDTEITA----HLSTHSQSFRKESSRPRGLPRTSSSAGSAFPDPSLPEFSLYPPPRRGGLDPVCEMDSSRSQRATESSEQADSGTPSTSGTEC-------------------TRYHLKEHRRLSRSVSRETGEGECAGEGGSGLYRSEGVQGGCERTGGHSAESLRSLSTRSSGSTESYCSGTDRDTNSTLSSLHSEQTSSTHVESLLSLSGD-------------------EKVNAGHADARNSN---------------------------------VASGEANKNPHAN-ELAIKLPTDDPPKS-------LNSESQQGEGTVEATSRTSADVSAGHQHQETEPDK-VRPKTVNLVHRAASS---SAATRSGRRRNGKQRASSFDASRHREYICGRGMA--KPRSAVFMKGEEDSSDQ--------------------SELSCASSLHSTHQLSTDSSS-STPHSCPSPEERRRPSLRAKMHGMPTSGQKVKEKERQKDKEKGKRRASRRTPSTGSAKTHARVLSLDSSTTACLNDPHHLGAPASSRPLTTS---------------KSDLEAKEGEVLDAASLLGRASQLESVTRSRNSLPCPISLSHTQDAMAGS-RAPGNDDTVTFRRERSTFRRQAVRRRHNAGSNSTPPASLIGSPLSLQEALSQVSQASGSQVRGQPSRTPSQVTVLSTSASLLVRNGS------------------------------------------------AQLEGCPDKASTVGVASLQDEFGKLTPPLYEVGGCDMSLVNFEPATRR---------------------------ASNNLWETDSHLSSSTSV--RFYPHDLFSFPQMRLNRLLSMDPELLEQHDVDGSPDLQEAPHGTQDSTHN----HPHTHALAHKTKQYYRF---WLLPYLWVGLHFDRLTLLALFDRNREVLENLLSVALAVLVAFLGSVLLVHGFFTDIWVFQFCLVIASCQYSLLKSVQPDSSSP--RHGHNRIIAYSRPVYFCLCCGLIWLLHYGSV---NCSTNAVSLYGVALTSSVLLSQARDLLIVFTLCFPVIFFIGLLPQINTFVMYLLEQLDIHFFGGNACTSLLSALYSVLRSIVTIAMLYGFCYGALKDSWDPQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLISLVQSKVFPNVKD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNPEDPLSEVQDPLPDKLRSSVNERLQSDVIVCVVIAVLYFAIHVSTVFIALQPFLSYVLYGLVGSVGLLTHYLLPQMRKQLPWYCFSHPLLKTREYYQFEIRGAAHVMWFERTHVWLLFVEKNILYPLIVLNELSGSAQELAG-PKKLNTEIGALVITIAGLKLLRSSFSSPTYQYVTVLFTVLFFTFDYRQFSETMLLDLFIMSIIFSKLWELFYKLKFVYTYIAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFVQAIVSAVFSTPLNPFLGSAIFISSYVRPVRFWEREYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLQLGRWGNYSTGDCFILASDYLNALVHLVEIGNGLITFQLRGLEFRGTYCQQREVEAITEGVEEDESCCCCEPGHLPHLLSFNAAFGQRWLAWEVLVTKYALEGYSITDNSAASMLQVFDLRRILTTYYVKGIIYYVIASPKLEEWLANEGLLEGLKSCGERNYVDLD-PTFNPNIDEDYDHRLAGISRDSFCSVYLSWIQYCNSRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------EKP------LDSEKDSLLVLLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFTDMELLRKVVVPGIRMSLKLHQDHFTSPDEYEESSVLFEAISSHEQTLVIAHEGDPAWRNAVLSNSPSLLALRHVLDEGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYCNTHPQLGHILGGPISIANIRNFIVNTWHRLRKGCGAGCNSGG-NVEDC--------------------DAGGLSCGSGNSGNSGTGASD--SQHSSGP-----------------------TALHAYT---PHSLG------TSQSSQSVQSGLVRQSPARASVVSQSSSYRHSS-----------SRQSSLRTSVTGLEPCRRS--SSSQLSLRTLPTSLQLRLGTNSSIANPEPPG--------PSSSLSAHSIPPCKRHAHTLAGLLGNEALVLG-TDIHPHPHHHLHYIHHHHHNPSLSCLRR---------DDISYRVQIVDVSQVLDVTNH------PKRKELVWPDESMRLRSGRNFWREWTPLEGMEGHVVHRWVPCSRDPVSRSHIDKTILLVQVDDKLVPIIETGVIELGAEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AU25-1", "uniprot_id": "A0A8I6AU25_RAT", "id": "A0A8I6AU25-1", "name": "Pecanex-like protein", "aln": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNS----------------------------------------------------------------------------------------TMGEQEEEAAQG-------ESSLPRDPG--VEMTVFRKVSSTPPVRCSSQHSVFGFN-------------------QVS------------ELLPRMEDSGPLRDIKELVREQG-------------------SNNVIVTSADREMLKLSSQENLIGDLPQTP--------------------PGVVPDPSLPSTDSSERSP----MAG-------------DAVPWGGSSV-ADTPMSPLLKGSLSQELSKSFLTLTRPDRALVRTSSRREQCRGTGG-------------------------------YQPLDRRGSGDPLPQK-----------------------------------------AGSSDSCFSGTDRET---LSSFRSEKTNSTHLDSPP---------------------------------------------------------------------GGHAPEGSDTDPPSEAELPAS--------------------PDAGVPSDDTLRSFDTVIGAGTPPGQTEPLLVVRPKDLALLR-------------PNKRRPPMRGHSPPGRTPRRPLLEG----------SGFFEDE-DTSEG--------------------SELSPASSLRSQRRYSTDSSS---STSCYSPESSQGAAGGPRKRRAPHGAEEGTAVPPKRPYG------TQRTPSTASAKTHARVLSMDGAGGDVLR-----------APLAGS---------------KAELEAQPGMELAAG----EPAMLPPEARRGPAANQPGWRGELQEEGAVGGAPEETGQRECTSNVR---RAQAIRRRHNAGSNPTPPASVMGSPPSSLQ----EAQRGRAASHSRALTLPS--ALHFASSLLLTRAGPN-----------------------------------------------VHEASNFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVSQPGEQA---------------------------ANG-AWDRHSHSSS-------FHSADVPEATGG-LNLLQPRPVVLQGMQVRRVPLEIPEE--------------QTLMEEAPPRAQHSYKY---WFLPGRWTSVRYERLALLALLDRTRGIMENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLK-VRPGSPNPQLSWGHNWVIAYSRPVYFCICCLLIWLLDALGT---AQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLTRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLVRSKLFPELEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSLETARAEPPDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVEAHTVVNHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFLQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVKSIIYYVSRSPKLETWLNHEGIAAALRPVRALGYADSD-PTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------SQP------VDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVMDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGG-NVDDS--------------------DCAGGGGLTSLSNNPPLAHPTPENTAGSSE------------------------QPLPPGPSWGPRPS------LSGSGDGRPPPLLQWPPPRLPGPPPAS-----------------------PAPTEGPRPSRPP--GPGLLNSE--GPSGKWSLGGRKGLGGP---------DGEPASGSPKGGTPKSQ-------------------------------------APLDLSLS-----------PDVSSEASPARTTQDIPCLDS------SVP-------ESCTPSGAPGDWP--VPVEERE------------SPAAQPLLEHQY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI59-1", "uniprot_id": "PCX3_MOUSE", "id": "Q8VI59-1", "name": "Pecanex-like protein 3", "aln": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRNS----------------------------------------------------------------------------------------TMGEQEEEAAQG-------ESSLPRDPG--VEMTVFRKVSSTPPVRCSSQHSVFGFN-------------------QVS------------ELLPRMEDSGPLRDIKELVREQG-------------------SNNVIVTSADREMLKLSSQEKLIGDLPQTP--------------------PGVVPDPSLPSTDSSERSP----MAG-------------DGVPWGGSGV-ADTPMSPLLKGSLSQELSKSFLTLTRPDRALVRTSSRREQCRGTGG-------------------------------YQPLDRRGSGDPMPQK-----------------------------------------AGSSDSCFSGTDRET---LSSFKSEKTNSTHLDSPP---------------------------------------------------------------------GGHAPEGSDTDPPSEAELPAS--------------------PDAGVPSDDTLRSFDTVIGAGTPPGQTEPLLVVRPKDLALLR-------------PSKRRPPMRGHSPPGRTPRRPLLEG----------SGFFEDE-DTSEG--------------------SELSPASSLRSQRRYSTDSSS---STSCYSPESSQGAAGGPRKRRAPHGAEEGTAVPPKRPYG------TQRTPSTASAKTHARVLSMDGAGGDVLR-----------APLAGS---------------KAELEAQPGMELAAG----EPAVLPPEARRGPAANQPGWRGELQEEGAVGGAPEETGQRECTSNVR---RAQAIRRRHNAGSNPTPPASVMGSPPSSLQ----EAQRGRAASHSRALTLPS--ALHFASSLLLTRAGPN-----------------------------------------------VHEASNFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVSQPGEQA---------------------------ANG-AWDRHSHSSS-------FHSADVPEATGG-LNLLQPRPVVLQGMQVRRVPLEIPEE--------------QTLMEEAPPRAQHSYKY---WFLPGRWTSVRYERLALLALLDRTRGVMENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASP--MHGHNWVIAYSRPVYFCICCLLIWLLDALGT---AQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLTRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVAMSYHLSRQSSDPTVLWSLVRSKLFPELEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSLETARVEPPDPLPEKMRQSVREVLHSDLVMCVVIAVLTFAVSASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCAEKYLIYPAVVLNALTVDAHTVVSHPDKFCLYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFLQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLITFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILVTYYVKSIIYYVSRSPKLETWLNHEGIAAALRPVRALGYADSD-PTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------SQP------VDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVMDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPVSLGAIARWLLRSWERLHKGCGAGCNSGG-NVDDS--------------------DCGGGGGLTSLSNHPPLAHPTPENAAGSSE------------------------QPLPPGPSWGPRPS------LSGSGDGRPPPLLQWPPPRLPGPPPAS-----------------------PAPTEGPRPSRPS--GPALLNSE--GPSGKWSLGGRKGLGGP---------DGEPASGSPKGGTPKSQ-------------------------------------APLDLSLS-----------PDVSSEASPARTTQDLPCLDS------SIP-------EGCTPSGAPGDWP--VPAEERE------------SPAAQPLLEHQY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6A9-1", "uniprot_id": "PCX3_HUMAN", "id": "Q9H6A9-1", "name": "Pecanex-like protein 3", "aln": "MGSQVLQILRQGVWASLTGGWFFDPHQSTFSNCFHLYVWIFLLIFPFLLYMVLPPSLMVAGVYCLVVAVIFATIKTVNYRLHAMFDQGEIVEKRSS----------------------------------------------------------------------------------------TMGELEEEPAQG-------DSNPPRDPG--VEMTVFRKVSSTPPVRCSSQHSVFGFN-------------------QVS------------ELLPRMEDSGPLRDIKELVREQG-------------------SNNVIVTSADREMLKLSSQEKLIGDLPQTP--------------------PGAVPDPSLASTDSSEPSP----LAG-------------DGAPWSGSSM-ADTPMSPLLKGSLSQELSKSFLTLTQPDRALVRTSSRREQRRGAGG-------------------------------YQPLDRRGSGEPTPQK-----------------------------------------AGSSDSCFSGTDRET---LSSFKSEKTNSTHLDSPP---------------------------------------------------------------------GGPAPEGSDTDPPSEAELPAS--------------------PDAGVPSDDTLRSFDTVIGAGTPPGLAEPLLVVRPKDLALLR-------------PSKRQPPLRRHSPPGRAPRRPLLEG----------GGFFEDE-DTSEG--------------------SELSPASSLRSQRRYSTDSSS---STSCYSPESSRGAAGGPRKRRAPHGAEEGTAVPPKRPYG------TQRTPSTASAKTHARVLSMDGAGGDVLR-----------PPLAGC---------------KAELEAQVGVEQAAS----EPVVLPAEARRGPAANQPGWRGELQEEGAVGGAAEETGRRDRSSSVR---RTQAIRRRHNAGSNPTPPASVMGSPPSSLQ----EAQRGRAASHSRALTLPS--ALHFASSLLLTRAGAN-----------------------------------------------VHEACTFDDTSEGAVHYFYDESGVRRSYTFGLAGGGYENPVGQQGEQT---------------------------ANG-AWDRHSHSSS-------FHSADVPEATGG-LNLLQPRPVVLQGMQVRRVPLEIPEE--------------QTLMEEAPPRAQHSYKY---WLLPGRWTSVRYERLALLALLDRTRGVLENIFGVGLSSLVAFLGYLLLLKGFFTDIWVFQFCLVIASCQYSLLKSVQPDAASP--MHGHNWVIAYSRPVYFCICCLLIWLLDALGS---AQPFPPVSLYGLTLFSASFFFCARDVATVFTLCFPFVFLLGLLPQVNTCLMYLLEQIDMHGFGGTAATSPLTAVFSLSRSLLAAALLYGFCLGAIKTPWPEQHVPVLFSVFCGLLVALSYHLSRQSSDPTVLWSLIRSKLFPELEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSLETARAEPPDPLPDKMRQSVREVLHSDLVMCVVIAVLTFAISASTVFIALKSVLGFVLYALAGAVGFFTHYLLPQLRKQLPWFCLSQPVLKPLEYSQYEVRGAAQVMWFEKLYAGLQCVEKYLIYPAVVLNALTVDAHTVVSHPDKYCFYCRALLMTVAGLKLLRSAFCCPPQQYLTLAFTVLLFHFDYPRLSQGFLLDYFLMSLLCSKLWDLLYKLRFVLTYIAPWQITWGSAFHAFAQPFAVP------------------------------HSAMLFVQALLSGLFSTPLNPLLGSAVFIMSYARPLKFWERDYNTKRVDHSNTRLVTQLDRNPGADDNNLNSIFYEHLTRSLQHTLCGDLVLGRWGNYGPGDCFVLASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPRVLSFNAAFGQRWLAWEVTASKYVLEGYSISDNNAASMLQVFDLRKILITYYVKSIIYYVSRSPKLEVWLSHEGITAALRPVRVPGYADSD-PTFSLSVDEDYDLRLSGLSLPSFCAVHLEWIQYCASRR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------SQP------VDQDWNSPLVTLCFGLCVLGRRALGTASHSMSASLEPFLYGLHALFKGDFRITSPRDEWVFADMDLLHRVVAPGVRMALKLHQDHFTSPDEYEEPAALYDAIAANEERLVISHEGDPAWRSAILSNTPSLLALRHVLDDASDEYKIIMLNRRHLSFRVIKVNRECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPLGYPIYVSPLTTSLAGSHPQLRALWGGPISLGAIAHWLLRTWERLHKGCGAGCNSGG-NVDDS--------------------DCSGGGGLTSLSNNPPVAHPTPENTAGNGD------------------------QPLPPGPGWGPRSS------LSGSGDGRPPPLLQWPPPRLPGPPPAS-----------------------PIPTEGPRTSRPP--GPGLLSSE--GPSGKWSLGGRKGLGGS---------DGEPASGSPKGGTPKSQ-------------------------------------APLDLSLSLSL-----SLSPDVSTEASPPRASQDIPCLDS------SAP-------ESGTPMGALGDWP--APIEERE------------SPAAQPLLEHQY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4AB99-1", "uniprot_id": "D4AB99_RAT", "id": "D4AB99-1", "name": "Pecanex-like protein", "aln": "MASQVLQLLRQGVWAALTGGWYHDPEHSKFTNSCHLYLWLFLLLLPLALHLAFPPNLLTALFYCGSVTIFFTVIKLISYRLHLMFDKGEVIQHRSPR--------------------------------------------------------------------------------------KRSKRRPEGEASSQHPPRHKIPSNNRQIHS-TKKEESR-SLTTPPLCCSSRGQSVHSQ-------------------HSS-----------GPLELPAQETVEDLKGVVLSEDQP-------------------EALVSSTSPGMKSESLPASQGRTPEPTPRP---------------------PCPVKPVTTEIFPARRVK----ESG--------------GTAQRPARHRSESGLVNTEALKKLPHLSLSQYDLLETDISFQPWGSEHSVLIPQPN------------------------------CPHAPTRAQPQSRSPQD----------------------------------------SQSSSFCQCNTVIAKPTEEELTR-----TSGQVELPS------------------------------------------------------------------------NPEVVDSDGEVEVTLIDT------------------SQPGEPLSLHEPIRIVITMSSTPNSISDPESSLHLRVTSSDRTG-----------VRPNAENAGPGGADPADPEQARIPLITLELTEDGRGGGGPSCPEGNGGER--------------------TPEKMEV-MSPDRRSSSGVGECS-----TKDESPTPGPTFVPLTPRADPESEGSREGPANLDP--------ASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSDSEKPIPTS---------------KSDLEAKEGQIPNESNFLEFVSLLESISTSKAVAP---DSAAEQKGVNQGPEGHASPGIKEEAVEN----EKSNGRDPKPGKPDLPSQDPASASPVLTQ----PPKTTALFQGSRQRHIIYRVTSQQDSSVLQVISGP--------------------------------------------------ETSVQEEMSLDAMHIFIDEHGEVRSCYLKSGNQKEGSSQHPPLNPD---------------------------CVSHAREILLSSSSTTTTGSPDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEDS--------------SRSSAQGKFNREQFYKF---IIFPGKWIKVWYDRLTLLALLDRTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSLLKSVQPDPASP--IHGHNQIIAYSRPIYFCMLCGLILLLDAGAK---ARHPPSYVVYGLKLFTPETLQSVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAVSGITSAVYSVGRSVLAAALLHVFCFSAVKEPWSTQHIPALFSAFCGLLVALSYHLSRQSSDPSVLLSFIQCKLLPKCLH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLDESAA---DPLPQRMKDSVKDVLRSDLIICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLITHHLLPQLRKHHPWMWISHPVLKSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNAVTLDAFSISN-YRRLGTHWDIFLMITAGMKLLRTSFCNPVHQFANLGFTVVFFHFDYKDVSESFLLDFFMVSIVFTKLGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPPKKHKCIVKEPWSQFNVGTTDPQHFTADDTSCQCLCSVTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTQRVDNSNTRLAVQMERDPGSDDGSLNSIFYEHLTRTLQDSLCGDLALGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITRTQYILEGYSIIDNNAATMLHVFDLRRVLIRYYIKSIIYYMVTSPKLASWVKNESLLKSLEPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCSVFLEWIQYCAGKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QELSKTLDHVDSDEDSALVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVT-ARDEWVFADMDLLHKVVVPAIRMSLKLHQDQFTCPDEYEDPEILYEAIQSFEKKVVICHEGDPAWRGAVLSNKEELLTLRHVVDEGANEYKVIMLHRGFLSFKVIKVNKECVRGLWAGQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQSVWGGPITLNRVRTWFQTRWLRMRKDCSVGQRSGG-NIEDG--------------------EGAVPP---GGNAPSGESRDSSTEQPRKGG-------------------TQQWASPRGEAPRAGRRKG------RSQSVQAHSAISQRRPTLSSSGPILES------------------HQAFLQTSTSVHELAQRP--SGSRPSLNTSAGSLHSQPPPVLTTGPYLGIQ-------HQAEALIQSSLGSST------------------------------------SSTLSFLFGKRS-----FSSALVISGLSAAEGGNTSDTQSS------SSVNIVMGPSARAA---ARHFSEPCEPIDSPEQGQLQD----GRLAEAAGENPRGVLCRRASQEDMGLDDTASQQSTSDEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DU28-1", "uniprot_id": "PCX2_MOUSE", "id": "Q5DU28-1", "name": "Pecanex-like protein 2", "aln": "MASQVLQLLRQGVWAALTGGWYHDPEHSKFTNSCHLYLWLFLLLLPLALHLAFPPNVLTALFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPR--------------------------------------------------------------------------------------KRSKRKPEGEASSQHTARHKNPSNNRQIHS-TKKEEPRGSLTTPPLCCSSRGQSVHSQ-------------------HSS-----------GPLELPAQETVEDLKGVVLSEDQP-------------------EALASSTSPGMKSESLPASQGRTPEPTPRP---------------------ACPLKPVTTELFTARKGK----ESG--------------GTAQRPARHRSESGLVNPGALKKLPQLSLSQYDLLETDISFQPWGSEHSVLLPQPN------------------------------CTQGATRAQPQNRSPQD----------------------------------------SLSSSCCQCNTVLAKPTEEELTR-----TSGQVELPL------------------------------------------------------------------------NQEVVDSDGEVAVTLIDT------------------SQPGEPLSLHEPIKIVITMSSTQNSISDLESSLHLRVTSSDRTS-----------VRSSAESAGSGGAGPADPEQVRIPLITLELTEDG-GGRGVSCSEGNGGER--------------------TPERMEV-MSPDRCSGSGPGDG----------SPTPGSTLATLTPRVDPESEGSKEGQANLDP--------ASCKSSHEKRHARVLSVDSGTDVFLSRSTKEVVSDGEKPIPTS---------------KSDLEAKEGQIPNESNFLEFVSLLESISTSKVVAP---DSPAEQKGASQGPEGHASPGTKEEAVEN----EKPNGRDPKPGKPDLPSQDPANGSPVFTQ----PAKSAALFQGSRQRHIIYRVTSQQDSSVLQVISGP--------------------------------------------------ETSVQEEMSLDAMHVFIDEHGEVRSCYLKSGNQKEGSSQHPPLNPD---------------------------CVSHARGILLSSSSSTATGSPDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEDS--------------SRSSAQGKFNREQFYKF---IVFPGKWIKVWYDRLTLLALLDRTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSLLKSVQPDPASP--IHGHNQIIAYSRPIYFCMLCSLILLLDAGAK---AKHPPSYVVYGLKLFTPETLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAVSGITSAVYSVGRSVLAAALLHAFCFSAVKEPWSTQHIPALFSAFCGLLVALSYHLSRQSSDPSVLLSFIQCKLLPKCLH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLEESAT---DPLPQRMKDSVKDVLRSDLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLITHHLLPQLRKHHPWMWISHPVLRSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISN-YRRLGTHWDIFLMITAGMKLLRTSFCNPVHQFANLGFTVIFFHFDYKDISESFLLDFFMVSIVFTKLGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIP------------------------------HSAMLFFQTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTRRMDNSNTRLAVQMERDPGSDDNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITRTQYILEGYSIIDNNAATMLQVYDLRRVLIRYYVKSIIYYMVTSPKLVSWVKNESLLKSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QELSKTLEHVDSDEDSALVTLAFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVT-ARDEWVFADMDLLHKVVVPAIRMSLKLHQDQFTCPDEYEDPAVLYEAIRSFAKKVVICHEGDPAWRGAMLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWAGQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQSVWGGPVTLNRVRTWFQTRWLRMRKDCSVGQRSGGGNIEDG--------------------EGGAVPSAGGGSAPNGESRDGSTEQPRKGG-------------------TQQWSSPRGEAQRAGRRKG------RSQSVQAHSAISQRPPTLSSSGPILES------------------HQAFLQTSTSVHELAQRP--SGSRLSLHTSAASLHSQPPPVTTTG-HLSVR-------ERAEALIRSSLGSST------------------------------------SSTLSFLFGKRS-----FSSALVISGLSAAEGGNTSDTQSS------SSVNIVMGPSARAAGHAARHFSEPCEPTDSPEQGQLQD----GRLAEAMEEN-LGVLCRRASQEDMGLDDTASQQSTSDEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKB5-1", "uniprot_id": "PCX2_HUMAN", "id": "A6NKB5-1", "name": "Pecanex-like protein 2", "aln": "MVSQVLQLLRQGVWAALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSR--------------------------------------------------------------------------------------KEEKPNKDKEAKGEHITNHRNPSNNRQIHN-GKKEEASRNLSTPPLRCSSRGQSITSH-------------------HSS-----------GPLELSAQETVEDLKGVILLEDHP-------------------IAPVSSTSPGIKVESLPASQAHMLETTTKS---------------------VIPVKPVATETLINGKGK----ERG--------------GKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIPEPVS-----------------------------CPRGSIRERVQSKSPQD----------------------------------------SLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPL------------------------------------------------------------------------HQEVDSSDSEVAVTLIDT------------------SQPGDPLSLHEPIKIVITMSSTPNSMTDLESSLHLRVVGTEKTS-----------VKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGG--GGGVPCPEGNGSER--------------------TPERLKTRVSTNQCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDP--------SSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKTMPTS---------------KSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILEN----EKPSGHSSKQGKPDLQSQDHTSTGPACTQ----PAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGP--------------------------------------------------ETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND---------------------------CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEAS--------------SCSSTQGKFNREQFYKF---IIFPGKWIKVWYDRLTLLALLDRTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSLLKSVQPDPASP--IHGHNQIITYSRPIYFCVLCGLILLLDTGAK---ARHPPSYVVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAVSGITSAVYSVARSVLAAALLHAVCFSAVKEPWSMQHIPALFSAFCGLLVALSYHLSRQSSDPSVLMSFIQCRLFPKFLH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLAESAA---DPLPKKMKDSVTDVLKWDLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVTHYVLPQLRKHHPWMWISHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISN-HRRLGTHWDIFLMIIAGMKLLRTSFCNPVYQFINLSFTVIFFHFDYKDISESFLLDFFMVSILFSKLGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIP------------------------------HSAMLFFQTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTRRVDNSNTRLAVQIERDPGNDDNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITQTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLLKSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QEPSTTLD---SDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHVLFKGDFRIT-ARDEWVFADMDLLHKVVAPAIRMSLKLHQDQFTCPDEYEDPAVLYEAIQSFEKKVVICHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWAGQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKNIWGGPITLDRIRTWFWTKWVRMRKDCNARQHSGG-NIEDV--------------------DGGGAPTTGGNNAPSGGSQESSAEQPRKGG-------------------AQHGVSSCEGTQRTGRRKG------RSQSVQAHSALSQRPPMLSSSGPILES------------------RQTFLQTSTSVHELAQRL--SGSRLSLHASATSLHSQPPPVTTTG-HLSVR-------ERAEALIRSSLGSST------------------------------------SSTLSFLFGKRS-----FSSALVISGLSAAEGGNTSDTQSS------SSVNIVMGPSARAASQATRHLSEPCEPPDATEQGQLHD----RCLAEAVADT-LGVVCRRASQEDMGLDDTASQQSVSDEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18490-1", "uniprot_id": "PCX_DROME", "id": "P18490-1", "name": "Protein pecanex", "aln": "MGSQTLEILRQGVWASLTGGYFYDPHQGVFCNVVHLYLWLYLLCSPFVAYLYFPSTWLTWCLYCVITSLTILMVKLANLALHRLYDRAQTMSEGNLKGQFVKVTKETEPRHDDEGGIEMKVIRPGGSRISGEQAINEASEENSIMSIDNVNSIIDLKVDVHRKNSSESIELMFYAPSMLSGGSQQDQQSLAGSASVSKSIRSTGPGGNSSTSAAAQADMFNKYLTVYPEVVEAAGSSAGSADGGSSGGDSRSGAAVSTLGHTGAGTAPAQHVRTGHLSRKCSEVFSRRHRRRLERQSSLDTAAAAANSNAENKLMRNQSDTIATAAPSFLHSQPTNKARGQTNPRQHFITSAPSTGIGGGDAPTSSTAVVVIAPASNSLVNPGRSSRLQRHRSSETHDERLKHQSRGGLFQPILQLPHHSAASSIGALAVLGGGGNVAANDVEDMELGLVRNAGSGGVADACSRALQSWILDPFPDGYLEDDSYTKSDLGIEQPHQPTFRTQHRHHHHHHHLHHHLGGAIIRKDPTSTMSALQLAAVTQPGTGGSVTGGGGAAGGGGSAAGMKRRRHSNATSYKHGSSQSNKSSLVGGGGSRGP-----------------SGEAGTSGGAGGTGGVRRIKSAALEVLCPQPSVSNLSPHPNSVEAISGQQQMRNPLPPPSKSLVRNQHLNLYPTQGYGDGTPSAGGGGPGNSSTCSSLFFGSSSACGSTTALIEPPVYPIVEHSDEKTAHEEHGDDCLGIGQGNADDDDEVDDVPIRRRTRALGCSQTHYSVESDVGGFLADEVGADEDVFKDFDDNLEHILSELQQTHNQLDDVLKTHDLHHHSHLHHHKAASVEGAGPSGGSVAVGVSAGNDDEDEETEDNNTGSRSPLLNDRNRQPATLREIQADKQLRQELSHQSGAVIPAPNPPVPIRSEADSGCPSSDCEQVSASSKDQLLSGIELELQQYQILQRCQLDEEQPCTSKMAAKSLGAIPKVVKYREVDELRRRRRGGSPADAAEAGNEFALVKQTKQASRNSSSSNSTHSISLTDSLTADIHKMLWLMHGGAVDDRGRPITGTSADGTPIPASSSLVPPNMSNAHFQFYQDAIQALQGTHPTSGSSVEHMTNIELARDKLRLDAKLMCEQLVAAAEANSGVRGNTLATQQMTQQQVGMLMRGGSSSRHPSSAPFSVQGLINVIRSERPAARSQLDALQQLSDAAAALAANASEAASVSASGAGGGASSGGGGVLSALGLANHPSNQISQISQLSQMSQPMLNVDGHFAPYCDYWRPACLLSATEKPAAPKSFYKYRFKWCGQEHEFKIAMDRLELLALFDRDLHWMHVLLASLLCTLVACLGAAILQHDHYKDLCALLFCAVIAGAQYSLVKSVQPDAASP--VHGFNKTVAYSRAIYFCLAGGMLLLLKRLDTDYGERTPDPVVFFGMRYSPADVVALLLQALYILLLCFPIIFSVGLCPQINTFLMYLLEQIDMHVFGGNAASSLLGSFLCVVRSVLAVMLLYGPLYGALDEQRGTQYI--LFSIFCAMLVPLGYHLSRCASDFSHLWRLIKTCIVSTYRDDEDEDLSQMQHIATGTVTGSGTANSTALQLTTSTPKQHRQTDVKTEHEQIELSSLEKLTVNEEHHEKDHGADDQLETDQDLPLQQKHSKSKTSSLGSSQQTLGKTISSSKRAITASSSCTSIGTGEPAVEAGALTEEAVEGEEQRRNTLAGEVGSKHELAENYDQAAKIDECEDKISSSSATNPGDMSTLTAGAGTATTDATPACLEADPDAEAEAPADEKQHQGILGTGTGTGTGTTEASENGSGGGANGNTNSNGTGNDLPDPLPRKLQATVTTRLKNDLVVMTLLAVSVLGLHCSTVFTALQPDLNVVLYSFIGVLGLLLHYIVPQMRKHMPWLCFSRPLLRQREFGQFEVLNAPKIMWFEKLYIYLSVLERNVLFPLLAISSLTADSQLIVA---KFGLPWGTLIVAICALKFVRNAYSDPTNQYLIIIFTVLLFRIDFAMATETFIIDYFFVSLAFRKCCDFLLKLQFIVTYIAPWQITWGSAFHAFAQPFSVP------------------------------HSAMLFLQAAISAVLSTPLNPFLGSAIFLTSYVRPIKFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLTRSLQHSLCGDLLMGRWGNVNQGDCFVLASDDLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREVEAITEDVEDNDGCCCCDPGHLPQLLSANAMFSTRWLAWQVVAAQYVIEGYSISDNLASATLQVFEYRKVLITYYIKSIIYYVVKNPKLEQWLASGPIQDALQHTLSRQFVDLD-PIFNFNLDEDFDFRAVGITRSSFCYVYLKWINYCVDMRRDANSMGGAPPAQAPAAAGGASSAPATAGVAPPAPVTPAHNDSKSTPNLSAHGGQAGPSSGQSKSQSQQQLRRPQKSVAQETSVGGGGVVVGGTTVPGTGGVTGGGGDPQLSSSHSFANISRQTSESAPGLGGYVAYMDQNVFVKLAKSSTTTGAGAGAPTSRKESQEKPALRLKLASVGKDAPLVSLCLALGLLARRSLATASHSALTGVEFFLHGLHALFKGDFRITSPRDEWVFADMELLHSVVAPAVKMALKLQQDHITNPDEFLDPHALYDAIDNCSNELVISHEADPVWRSAVLRGAPNLLALRHVMEDGSDEYRIIRLTKRCLSFRVIKLNRECVRGLWAGQQQELIYLRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYVSPLTTSYADTNAQLCEVIGGAITLDTIRHTVLGWWHRIRERCRQGCSSGS-ALEPHPGSGPVQLGACNFGSGGSVVGAASTATGVGASTGSGLGVAAPGTAGSTGGESGDLAPVFISAPLYNTLTVNSYYSVRPGNVPGGPIPGNLGGNYVSDSLAVVRGGLAVMPVKPTSTTLIAGLLNRERDETSGSGIMGAGASGPTRATSSGGVRSRRPEVGSSRGRDHERRATLPIASGGAGGEPGKDLTAPQTQVEHEPSPRSTKLSSSSGSLGLGMGVGLGNIITTPGDYPRKTKGPICLTAVDTGTSSSAAEGKPAGSGTVAGTGVGGVIRKPRIEIFKKVIIVDDTGIYDCLDIIDAVVWPTERMRNNGGRLSWKDWEPSAGMVGHVVHCWTPNHKDIRFRSHVNRYVYLVEIGDHYVPVEELGLREYNQIMGSTEEMANSRRSSIQRDFHEYNIQLKLAGLAPIIGGGESSTATTSDASKSHKAKIRAVSSSSSEDEDTSSTRSIPLPQGDDGDLTNFTRLVSMWKEIILDNNKRRLYDMGELSPELLQKLDDAVQQQQQLEDALAEESKEKGTATVTANEGEEGVGEMEIEPEQEQKEVVYLEEQSPLEEVTVSKPDEQPAQPTIPASPVPAETSSTSSAKSTSSPSLCQEEEDAVDPEETPELASEESPSDENGESEAGTTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **.*::*******:::**::.**.: * * ***:*: ** *: :: :*.. : .** : : :* . ** * .: :. .. . : . * .: . . * . :.. . . . .. * : . . : . : * . . * . .: . : . . . * : ** :.. . . :** : . . .. . . . : : :: . . . . . :: .. . * . . . : : *:: : :** ****:** . :.. * **: ** * :.. *: .: ** *:*..****:* *:*....* *.* ::***.:***: :: **. .:*: . . : :: *** : :** **:** ** **:*: ***.* :. :. .. *::: :*: .*: *:: *** **.:**.:.***** :** : * ::: :.. . . . **** :: :* *: *::: .* :.: **** *:. * **: : * :*:. *:::**:**: ** :*:*:*: *. * * . . :****: : * *: :::* : :. :: .: : : ::: ..:*::*.::. * *: : ***::* :*: :: :::* *::*: * ::: **:*: :*:****::***:**.*** *::* . * : :..:****.*:***.:*: **.**::***:.***:*:*:***** *::*: * **..***********:**.:***** :***** . ****:**** **.:**::* **** ***:****************** *. *:: . ***.***:*::** ** * ***:*:: ::* :***** ** *:: *:*:: *::* **:*.****: ..** *: : .*. . : * . *. .:*:*: *:: *:* :.*.**::* * : :: ** *. .* *.**:*.**:* .:: **:***.*******:: ****:*:**:**: **.*.::*::**:**::* ***: :. *::** : :**.**.**.**.*:* . .**:****:::.::**::* * : ***:***:*:**************::************* **.***:********:***::******* .:: ** : **.::: : . * *::: * **. :: . . . . . * * . . . . .: . . . : : . : : . * ", "identical_positions": 470, "similar_positions": 441, "identity": "13.55%" }, { "cls_id": "homologset.agr.FB:FBgn0003053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4K0-1", "uniprot_id": "A0A0G2K4K0_RAT", "id": "A0A0G2K4K0-1", "name": "Ras-responsive element-binding protein 1", "aln": "------------MTSNPP-----TGLEGSD------------------------------------------------LSSVNTMMSAVMSISSVT--ENGGSPQGIK-SPMKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDTNSTTAAAPPSPLKRRRLSSKRKLSHDAESEREDPGPAKKT--------VEDGQSSGLDKMADETFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHN-----ALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQTH------------IPADQGREKLQTKTLAADTLDQ---------------KVFLAFLGLQHTKDVKPAPAEELLP----DDSHTIQLQTLKCQLPQDPGCTNVLSLSPFEAASLGGSLTVLPATKENMKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQIS--LPPLSKAPATPLQAIFKHMPPLKPKPLVAPRTVVAASTPPP---LINAQQASPGCISPSLPPQSLKFLKGSVEAVSSAHLLQSKSGIQPNTSTQLFLQQPGVELPGQAEMKAQLEQDSIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGIS----PYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIQYVSSS----------TAELVDALCSPETVCRLCGEDLKHYRALRIHMRTHCSRGLGGCHKGRKPFECKECNAAFAAKRNCIHHILKQHLHVPEKD-------IESYVLATDAGLGPADT-AAEASSR-EESSCVTFA--------------------------------ECKPLTTFLEPQNGFLHSSPTQPLPSHISVKLEPASSFATDFN---------EPLDFSQKGLALVQVKQENMSSLLNSSSSSALYDCSMEPIDLSIPKSGKRGDKDTVVSSDAKKPE--------PEAGKAEQLSPHPPPCPTLSVTVEPKGSLDNPAGTVVAVTTAAKLEPHTQPLQGSVQLAVPIYSSALISNAPLLG-SSALLNSASLLRPLRPKPPLLLPKPAMT-----------------------------------------------EELPPLASIAQIISSVSSAPTLLKTKAADPGPSSTSSNAVATDSPGGSIPKAS---PSPTDIPSSREPTDPAPTASSPEEASPPEQGPAASS----RKRGRKRGMRNRPLPNSSAVDLDSSGEFASIEKMLATTDTN--KFSPFLQTAED-TQEEVAGTP-------ADHRGPTEEEQGSSAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPPKEGDVGSHDSTDSQSDTDTLTTPGEVLDLTA--RDKEQPTSEGASELSPATQDLTET-EAKAEAAPPEEEEEEKGTEENPEPELECRVEESSGDADAPEEDTASNQSLDLDFAT-KMMDFKLAESEAGAVDSQGPAQQEPK---HACNTCGKNFKFLSTLSRHRKAHGCQEPKEEEE-APSLENESLGRAVEGPSPSP-EPEETPAES--SATDPTAGTGEASGERQNEDTESPSDGEGTAEKRG----DSDRRPKTDSPKSMASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHG----KDSDKDERAEEGSEDESTHSANNPASENEAESAPSTSNHVAITRSRKESLANSGKECGR-EEKAIAEQATEPSAPKEPGSPGETDPQSPA--AIVQDLLELCGTRPA-PILAATDGASQLLGME--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UH06-1", "uniprot_id": "RREB1_MOUSE", "id": "Q3UH06-1", "name": "Ras-responsive element-binding protein 1", "aln": "------------MTSNSP-----IGLEGSD------------------------------------------------LSSINTMMSAVMSVASVT--ENGGSPQGIK-SPMKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHACSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDTNSTTAAAPPSPLKRRRLSSKRKLSHDAESE--DPGPAKKM--------VEDGQSGDLDKMSDEIFHCPVCFKEFVCKYELETHMETHS-DNPLRCDICCVTFRTHRGLLRHN-----ALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQSH------------IPADQGREKLQTKTLAAESLEQ---------------KAFLALLGLQHTKDVKPAPAEELLP----DDNQAIQLQTLKYQLPQEPGCPTVLSVSPLDAASLGGSLTVLPATKENMKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQIS--LPPLSKAPATPLQAIFKHMPPLKPKPLVTPRTVVAASTPPP---LINAQQASPGCISPSLPPQSLKFLKGSVEAVSNVHLLQSKSGIQPSTTTQLFLQQAGVELPGQPEMKTQLEQESIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGIS----PYQCNICDYIAADKAALIRHIRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSP----------TAELVDAFCAPETVCRLCGEDLKHYRALRIHMRTHCSRGLGGCHKGRKPFECKECNAPFVAKRNCIHHILKQHLHVPEKD-------IESYVLATNSGLGPADT-PTDAASRGEEGSCVTFA--------------------------------ECKPLATFLEPQNGFLHSSPTQPLPSHISVKLEPASSFAMDFN---------EPLDFSQKGLALVQVKQENVSSLLTSSSSSALYDCSMEPIDLSIPKSVKKGDKDTVVPSDAKKPE--------PEAGQAEPLSPRPPPCPTLSVTVEPKGSLETPTGTVVAVTTAAKLEPHTQPLQGSVQLAVPIYSPALVSNTPLLGNSAALLNNPALLRPLRPKPPLLLPKPSMT-----------------------------------------------EELPPLASIAQIISSVSSAPTLLKTKVADPGPSITSSNTVATDSPGSSIPKAA---ATPTDTTSSKESSEPPPAASSPEEALPTEQGPAATSS--SRKRGRKRGLRNRPLPNSSAVDLDSSGEFASIEKMLATTDTN--KFSPFLQTAEDDTQEEVAGAP-------ADQHGPADEEQGSPAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHT------------------------------------------------------DSQSDTDTLTTPGEVLDLTA--QAKEQPPAEGASEISPASQDLAIK-EAKAAAAPSEEEEE-KETEENPEPEEECRVEESTGAADAPEEDTASNQSLDLDFAT-KLMDFKLAESEAGSVDSQGPAQQEPK---HACDTCGKNFKFLGTLSRHKKAHSCQEPKEEEAAAPSLENEGVGRAVEGPSPSP-EPEEKPAES--LAIDPTPGTREASVAKQNEETEGPTDGEGTAEKRG----DGDKRPKTDSPKSMASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHG----KDSDKDERAEEDSEDESTHSATNPASENEAESAPSTSNHVAVTRSRKESLSTSGKECSP-EERAAAEQAAEPSAPKEQASPGETDPQSPA--AIVQDLLELCGKRPA-PILAATDGASQLLGME--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92766-1", "uniprot_id": "RREB1_HUMAN", "id": "Q92766-1", "name": "Ras-responsive element-binding protein 1", "aln": "------------MTSSSP-----AGLEGSD------------------------------------------------LSSINTMMSAVMSVGKVT--ENGGSPQGIK-SPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKM--------VEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHN-----ALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH------------VAADQGQEKPQATPLPGDALDQ---------------KGFLALLGLQHTKDVRPAPAEEPLP----DDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQIS--LPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPP---LINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGIS----PYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSS----------AAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD-------IESYVLAADG-LGPAEAPAAEASGRGEDSGCAALG--------------------------------DCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFN---------EPLDFSQKGLALVQVKQENIS--FLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE--------EEAGSSEQPSPCPAPGPSLPVTLGPSGILESP----MAPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVG-SSALLSGTALLRPLRPKPPLLLPKPPVT-----------------------------------------------EELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSVPKAAT-TATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTS----KKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTN--KFSPFLQTAEDNTQDEVAGAP-------ADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHT------------------------------------------------------DSQSDAETAAAAGEVLDLTS--RDREQP-SEGATELRQVAGDAPVE-QATAETASPVHREE-HGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFAT-KLMDFKLAEGDG-EAGAGGAASQEQK---LACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKG-------DGASTAEEGPQPAP-EQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHG----KDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASATKDCSHREEKVTAGWPSEPGQ-------GDLNPESPA--ALGQDLLEPRSKRPAHPILATADGASQLVGME--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TAJ7-1", "uniprot_id": "A0A8N7TAJ7_DANRE", "id": "A0A8N7TAJ7-1", "name": "Ras-responsive element-binding protein 1", "aln": "----------MEMESASPEKTISNGVGAADGNEQSHLSEEAVNSQSSTCTPEPVEEADFDETDKAADEDEVGVRTEEELTSINSMMSTVMNVGQINGVDSETPKTSPR-NTNKSPSAGRTGRRNQEVKDERSSFICPLCDKNCMTQHQLTMHIRQHNTDSGGTDHSCSICGKALSSASSLDRHMLVHSGERPYKCSVCGQTFTTNGNMHRHMKIHEKDSSGIPTPSSSPLNKRRRLSSKRKPSVEDEGEQAEEPPVKKVT------LIQKLKEDNSVKSEEEVFHCPICFKTFICKNDLEAHMETHP-DTTLRCNICCITFRKHRGLLRHN-----AAIHKQLPTDPSGRPFIQNNPSIPLGFGDLAFIDFSCQKFPQIAQVWCETNLRRCSSKFHKFVCEDCNKAFPIQQSLDLHKSSHNCSVDTSTDPQEHKADAVIDAPKVNSHSEDSKEVSELAPHVDTTSSDGKNGFMERLGLQHSSLAKLEKSEEQIQQEVLDSIRFIRVEPPSTNLPQETSGS--LGVSILEPVSLQAMN-----KNTALGLLSLQPLHA-----VVSNGMFVPISGQTAVELADIEQILKIATSVPPQMS--LSMLPKSLGSPLQVDPRQISSLKPKSLITPRSSMGASTPPPP--VMNAQQASSGNISPSLPPQTGQQVRTARQSS------ASSSSSTSSSPTNWETTQLGSDVIGNTIISYETG-----------------KQEEFDSKEKDMRVVP--KKT---AKTEYPCRFCKEVFSFLGGLQAHMRHHLGAS----PYQCTICSYAAPDKATLIRHLRTHSGERPYVCRLCHYPFTVKANCERHLRKKHMKNTRKDIEKNIEYVTTSSSISSVIGGTTLDLLDTTNAGNTSCRYCGEDLKNYRALQIHLRTHN-----GCQK--KPFECRQCGATFLAKRNCIHHLLKHHPDVPERE-------IEEHIKSLVPVGGEVNA-------------------------------------------------------QSNTSATNGLVNSS--------ISQNVGTFSGPVEEQE---------QPLDFSSK-----SQKTMPSVVKIEGAASPLLNDCSMEPIDLSIPKDPEKKKMRKEVPQNYQELN--------KEKTSETAPG-----------------------------------------LLAAIPVSIPSLASVLSS---------DITKPYTRLKPLLPKP----SSASST-----------------------------------------------AEMAPLASIAQIISSVSATPVLIETGMDAKNCISAVDFKTLSEN------------KSPIGTTKLDSVLNGSPDNSKK-------RG---------KKRVFQEEICDSRIAVGSGIDLESSGEFPSVEKMLATTDAN--KFSPYLQPNQMEPMMEEKEKQ-------SADEEVKEIREDKPKKPPQNKGKKNAYSNSVQKMTCPYCPRLFPWASSLQRHMLTHTGQKPYPCPQCDSFFSTKSNCERHLLRKHGVSN-------------------RALQNSGSRLKPKTDEESLGSTESVCDTEHPVAEGTMDLSSVNTKQEESPEAPERTGQSAPEQADSSTDPNQTQPAEENPEMVEKDDDDDDDDSQSSMSHEMSLVSNLVVDVQLSGEEQHQSKSAPEVVSPPDEFPHTCASCKKTFRHAATLSRHQKTH-LQEVQPEDG----AKKGRRQAPPQNPIPVPSKEMEQDAKSEDDEKEENSSCVESGVDEEEKEREDMSEDEEETPS-------SELQALEEEGNSTRGKADKRKKICTVCSKRFWSLQDLTRHMRSHTGERPYKCQTCHRTFTLKHSLVRHQRVHQKP--SDEKG----SDDAEMNEETDGAKDEAGVLEEKEFNEAVQSEAEHKEEEIGG-RMEEDDAKQLPEETSMGVNSAEEALPDEDEQ-------EEQQTEEPS--EEARSGCDPEPAKTSNHSCTVAQEDTEMPAQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4J1-1", "uniprot_id": "Q9W4J1_DROME", "id": "Q9W4J1-1", "name": "", "aln": "MLAAQQQHNNSTVESEMERQRRDSTTSESSLEHLDLGRTPKKLGGNSGSTQTTSTPHELATVTSSRKRKIRHLQLNHHQQQQHHQQSDLLSDEDVAEAEAEEDEDEEDGDQVAALGSRNLGRHKQRRSGGATTQASIVMDYSSGDASSLRKKFRLNRSAASLSESGFVDASSTTGHSGYLGNSSSATNTTATSGIGASAVAPSPVG--GAAINAASSSSGSSSGGSGGSSPQGQCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQVAQSQSQSQQQQSLQQQQQSQQQRRQQQQHQPSQQQQNPAQQQLMGNTLSARAESYESDASCSTDVSSGHSHSRSSSSLNNNN--------NNSHKANNNLKDLEELEVSTEDQDT---------------ENKQRRLKTTINNNIIESEQQEDMDDEE-ADDADVAMLTSTPDVATLLAGASASGAASRSPTPSPSASPALLLSCPACGASDFETLPALCVHLDAMHSDIPAKCRDCEVIFATHRQLQSHCCRLPNALAGGLPPLLGASSSPLHNEEPEDEEHGDDEDLEQKERLASQSEDFFHQLYLKHKTANGCGAISHPPSPIKHEPADTKDLADIQSILNMTSSSSSFLRNFEQSVNTPNSSQYSLDGRDQEEE---------------AQDAFTSEFRRMKLRG-----------EFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADTSFRSISPTPPPPPVNESKSQLKHMLLGENHLAPVNQQPPLKIQVKSLDQLVDKKPSAPAPQQQQQQQQQEKSGSALDFSMDVLDLSKKPTGGASLTPAVTRTPTPAAVAPVTPGGVGTPDLAAAIEQQQLLLAQQQLFGAGGEYMQQLFRSLMFQSQTSGFPFFPFMAPPPPQANPEKPPMVSPPNRINPMPVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNVAAAAAAAAAAAAATVMAGGPGSSGFGSNHHHGHGHGSHGSHGHAPISEQVKCAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLTNPSPMHNGSSQGNGQATAMDDDEPKLIIDEDENEHDHEVEAEDVDDFEEDEDEEEMDEPEDEPELILDEQPAEKEAEEEQELPKPLEQLGTKEAAQKMAETILEQAIKAGKPLSPPPTKENASPANPTVATTMQEPAITAPSTNPSSLKTMIAQAEYVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMGFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHT---------------------------------------------------------GQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKELELERERELERERELERERQLEKEKERERQQLIQKLAAQMNAAATAAAVVAAAS-AVNGGASGGPHGPIADALAGGDLPYKCHLCEGSFA-------ERLQCLEHIKQAHAHEYALLLAKG-----AIETESLEANPHQQPSQQAVHSDDE---------------APNGGGNRGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQVSSPPSTPHPTQPTSANNNNSCHNNNNNANNNNNNNNNNNNNNSSSKLGLKLHDLLDKASEWRASRLGEHKENMGEATPSGATVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. . : * ::. .: : . . .. . **::*. . :: . : : . .* ::* :.: :. :: . ...: . :. *.. . . . ... : :. * :: ...... . : . : : *** .. : . * : :. : . : * * * :* * : . *: *: .*. : .:.* * :** .: .: ** : :. . . :.: *:: * : . . :: * * :* *. * *. .: ..: *: . : . : : : * .. :* : . : : . . ::. . . . : .... . . .::.: . . . : : :* .*: . . * :: *. : : .:**: . . : : :.:.: : :::: * : * ** . : : . :. . . : . : *: .. : : :**::*. **. *:.* * *** *::*.:* * . ***:*:**:***.*:*** * :*:*.**.*********::* * :*::::: * * .: : : . ::. :: *: :: :: :. . . * .. ::: . *:. :: : * : . .*: . : . . : *: . . : *. . ::: .. .: :. . . . : : :: . . .** .. *: . .::* . ..: : . ::. .* . . . . . . : . ... :.* :: .: *:: .: :: *..:::. : * : . .: .. . *:.:*: . :::.**:* *:***:***:**:**** .. : * * . .* : . . . . * * : : . . : . .: : : . . : :*: .: : : . . . . : .: . *: . .: ::.* . .. . .:** :*:.* :**** :** ****:*:****::*: * *.******::** : *. . .*. : . . .. : . . .:. . .::. . : . . . . : . : :: ::: . ", "identical_positions": 170, "similar_positions": 460, "identity": "8.37%" }, { "cls_id": "homologset.agr.FB:FBgn0003062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVA5-1", "uniprot_id": "D3ZVA5_RAT", "id": "D3ZVA5-1", "name": "", "aln": "--MKPAG-----------GRGGWS-WGGGKGGGK------GGDTG-SGAKGGFGTRTRGGGGGGRGRGRGGGGGGGGGGGGGGGGGGGD-----RQRRGGPGRNKNRRKKG-ITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVTENGE-------KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVKKLQQENLKPQEQLTLEPYERDHAVVVGVYRPAPKSSSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WS3-1", "uniprot_id": "FBLL1_MOUSE", "id": "Q80WS3-1", "name": "RNA 2'-O-methyltransferase FBLL1", "aln": "--MKPAG-----------GRGGWG-WGGGKGGSK------GGDTG-SGTKGGFGARTRGSSGGGRGRGRGGGG--------GGGGGGGD-----RQRRGGPGKNKNRRKKG-ITVSVEPHRHEGVFIYRGAEDALVTLNMVPGVSVYGEKRVTVMENGE-------KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPPPKSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHQ2-1", "uniprot_id": "FBLL1_HUMAN", "id": "A6NHQ2-1", "name": "RNA 2'-O-methyltransferase FBLL1", "aln": "--MKSAASSRGGGGGGR-GGGGWGSWGGGRGGGGGAGKGGGGDGGGQGGKGGFGARARGFGGGGRGRGRGGGD---------GKDRGGG-----GQRRGGVAKSKSRRRKGAMVVSVEPHRHEGVFIYRGAEDALVTLNMVPGQSVYGERRVTVTEGGV-------KQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPLPKSSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35550-1", "uniprot_id": "FBRL_MOUSE", "id": "P35550-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "--MKPGFSP---------RGGGFG--GRGGFGDR------GGRGGGRGGRGGFGGGRGGFGGGGRGRGGGGGGFRGRG---GGGGRGGG-FQSGGNRGRGGGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22509-1", "uniprot_id": "FBRL_RAT", "id": "P22509-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "--MKPGFSP---------RGGGFG--GRGGFGDR------GGRGGGRGGRGGFGGGRGGFGGGGRGRGGGGGGFRGRG---GGGGRGGG-FQSGGGRGRGGGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKAKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22087-1", "uniprot_id": "FBRL_HUMAN", "id": "P22087-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "--MKPGFSP---------RGGGFG--GRGGFGDR------GGRGG----RGGFGGGRG-RGGGFRGRGRGGGGGGGGG---GGGGRGGGGFHSGGNRGR--GRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDD-------KIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1V3-1", "uniprot_id": "FBRL_DROME", "id": "Q9W1V3-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "-MGKPGFSPRGGGGGGGGGGGGFRGRGGGGGGGGGGFGGGRGRGG-GGDRGGRGGFGGGRGGGGRGGGGGGGRGAFGGRG-GGGGRGGG-GRGGGGRGGGGRGGGAGGFKGGKTVTIEPHRHEGVFIARGKEDALVTRNFVPGSEVYGEKRISVETNGE-------KIEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYRPPPKQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15646-1", "uniprot_id": "FBRL_YEAST", "id": "P15646-1", "name": "rRNA 2'-O-methyltransferase fibrillarin", "aln": "MSFRPGSRGG--------SRGGSRGGFGGRGGSR------GGARG--GSRGGFG-GRGGSRGGARGGSRGGFGGR-------GGSRGGA-----RGGSRGGRGGAAGGARGGAKVVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVVGRYMRSGLKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. ** * *. * * :** * ** ** . ** * . ** . :. * :***** **:* ** ** *** *:.** .****:*::: . * ***.**********.::**::::.: * ***********:******::**:*:*********.**:*:.:****.****::****** *****:.*** :********* **:***:: **:: * .:*****.*****...*:*** **:*:: :.:** ************.:*** * ", "identical_positions": 165, "similar_positions": 66, "identity": "46.09%" }, { "cls_id": "homologset.agr.FB:FBgn0003067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQJ7-1", "uniprot_id": "F1LQJ7_RAT", "id": "F1LQJ7-1", "name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "aln": "TLLPSPPSLTPRLHWFLWPSRSASPGAMAAMYLPGLRLSW--------HRLRPWCRSPCRSIQTLRVLSGDLSQLPAGVRDFVERSAHLCQPAGIHICDGTEAENAATLALLEEQGLIRKLPKYENCWLARTDPKDVARVESKTVIVTSSQRDTVPLLAGGASGQLGNWMSPDEFQRAVDQRFPGCMQGRTMYVLPFSMGPLGSPLSRIGVQLTDSPYVVASMRIMTRLGTHVLQALGD-GDFIKCLHSVGQPLTGHGDPVGRWPCNPEKTLIGHVPEQREIVSFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITNPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGQLRAINPENGFFGVAPGTSATTNPNAMATIQSNTVFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCVPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFSWRHGVFVGSAMRSESTAAAEHKGKTIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGARLPRIFHVNWFRRDEAGRFLWPGFGENARVLDWICRRLGGEDSARETPIGLVPKEGALDLSGLR-AIDTSQLFSIPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALEERVQKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH04-1", "uniprot_id": "PCKGM_MOUSE", "id": "Q8BH04-1", "name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "aln": "---------------------------MAAMYLPGLRLSR--------HGLRPWCWSPCRSIQTLHVLSGDMSQLPAGVRDFVARSAHLCQPEGIHICDGTEAENTAILALLEEQGLIRKLPKYKNCWLARTDPKDVARVESKTVIVTPSQRDTVPLLAGGARGQLGNWMSPDEFQRAVDERFPGCMQGRIMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGD-GDFIKCLHSVGQPLTGHGDPVGQWPCNPEKTLIGHVPDQREIVSFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITNPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGQLRAINPENGFFGVAPGTSAATNPNAMATIQSNTLFTNVAETSDGGVYWEGIDQPLPPGVTITSWLGKPWKPGDKEPCAHPNSRFCVPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKTIMHDPFAMRPFFGYNFGRYLEHWLSMEGQKGARLPRIFHVNWFRRDEAGRFLWPGFGENARVLDWICRRLEGEDSAQETPIGLVPKEGALDLSGLS-AVDTSQLFSIPKDFWEQEVRDIRGYLTEQVNQDLPKEVLAELEALEGRVQKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16822-1", "uniprot_id": "PCKGM_HUMAN", "id": "Q16822-1", "name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "aln": "---------------------------MAALYRPGLRLNW--------HGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTVPLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGD-GDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLR-AIDTTQLFSLPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07379-1", "uniprot_id": "PCKGC_RAT", "id": "P07379-1", "name": "Phosphoenolpyruvate carboxykinase, cytosolic [GTP]", "aln": "---------------------------MPPQLHNGLDFS-------------------------AKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQS-QLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGD-GEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLG-DVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2V4-1", "uniprot_id": "PCKGC_MOUSE", "id": "Q9Z2V4-1", "name": "Phosphoenolpyruvate carboxykinase, cytosolic [GTP]", "aln": "---------------------------MPPQLHNGLDFS-------------------------AKVIQGSLDSLPQAVRKFVEGNAQLCQPEYIHICDGSEEEYGQLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKTGLS-QLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGISVLEALGD-GEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDAEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPEGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKDGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYIPKENALNLKGLG-GVNVEELFGISKEFWEKEVEEIDRYLEDQVNTDLPYEIERELRALKQRISQM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35558-1", "uniprot_id": "PCKGC_HUMAN", "id": "P35558-1", "name": "Phosphoenolpyruvate carboxykinase, cytosolic [GTP]", "aln": "---------------------------MPPQLQNGLNLS-------------------------AKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLS-QLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGD-GEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLG-HINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRISQM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20007-1", "uniprot_id": "PCKG_DROME", "id": "P20007-1", "name": "Phosphoenolpyruvate carboxykinase [GTP]", "aln": "---------------------------MPELIEQSKIISGNVCGLPQLHKLRQDNCGLYSHIRGIPISYGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENKVLIKSLLEAGTIVPLPKYDNCWLARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWISPSDMDAAVQQRFPGCMKGRTMYVVPFSMGPVGSPLSKIGIELTDSAYVVASMRIMTRMGAAVLRQLAKKEEFVRALHSVGAPANGQVEQP-SWPCDPERTIILHKPAENLIVSYGSGYGGNSLLGKKCFALRIGSTIAKQEGWLAEHMLILGITDPKGEKKYITAAFPSACGKTNLAMLNPSLANYKVECVGDDIAWMKFDSQGVLRAINPENGFFGVAPGTSMETNPIAMNTVFKNTIFTNVASTSDGGVFWEGMESSLAPNVQITDWLGKPWTKDSGKPAAHPNSRFCTPAAQCPIIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSMEKR--GQVPKIFHVNWFRKSAEGKFMWPGYGENSRVLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMKDKVDVKEIFSLPKEFWSQEVKDIRTYFESQVGADLPASIYQQLDELSSRVDNL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . :. : *.:. *. :* *: . **** :*****:* * : : : * : * **.***** *:* ****:**:*.* * :.:*:* * **.*:* ::: *.: ******:** ***:******:****::**::****.***********:* **. :.. :*::.***** * : *.*:** *:* * * .. *:*:******************:.* :*::**************.* *:*:*::**************:.*:*..:************:**::* ****************** *** *: *: .**:*****.******:***::..*...* :*.* .* * . :*.********.** ****:* *** * ****..::****** ****:*** .* ****:*:*****:********* ***************** *: ***** : .::*:********:. *:*:***:***:***:*: *: *: . :.** :* *.**:*.*: :: ::*.:.*:**.:**.:* *: .**. *** .: :: *. *: ::", "identical_positions": 342, "similar_positions": 155, "identity": "50.52%" }, { "cls_id": "homologset.agr.FB:FBgn0003068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJE2-1", "uniprot_id": "PER3_RAT", "id": "Q8CJE2-1", "name": "Period circadian protein homolog 3", "aln": "-----------------------------------MDP--CGNPAVPGGDCPQTRGPG--------------LQGSS--------------------------GQEGPLQGICVDSS----------------------------------------------------HSEHE---------DRNRMSEELIMVVQEMKKYFPAERHT---KPSTLDALNYALRCVHSVQANSEFFQSLSPRGAR--QAEATVYNLEELTSLASEHTSKNTDTFVAVFSFLSGRLVHISEQAAWILNSKKGFLKSLHFVDLLAPRDVRVFYAHTAP-TQLPFWNTWTQRAS-QYECAPVKPFFCRICGGG-DREQKRHYSPFRILPYLVHVHSPAQPEPE-------PCCLTLVEKIHSGYEAPRIPVDKR--VFTTTHTPGCVFLEVDERAVPLLGFLPQDLIGTSILTYLHPEDRPLMVAVHQKVLK--YVGHPPFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFIIGRHKVRTSPLNEDVFATRIKKAT-SHDEDITELQEQIHRLLLQPVHASASSGYGSLGSSGSQEQHISVTSSSESSGH-------CVEEAQQEQMTLQQVYASVNKIKNVGQQLYIESMARSSVKPVMETCTEPQGSDEQK-----DFSS-SQTLKNKS-TDTGSGGDLRPEQHSSSYQQMNCIDSVIRYLTSYSFP-ALKRKCISCTN-TSSSS---EEAKPNPEAD--GSLRDTEQLLDIPEQE--TTTPSADAEGG--VARTLSTAALSMASGVSQCSCSSTTDHVPPLQSE---------------------------------SVAGACEPWALRTKA-HVTAEGFK-----------PVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQEGRNHAKYACVVGAGATPKHSRC---------AGSERRKHKRKKLPTPVDSSSSSAHLCPHVRGLLP-----DVQHWSASVT-SPCATGLALPSALVVPNQTPYLLSSFPLQDMA--------PHGVGDSAPWGAAAECP--PLSAGPHPVSTFPSAYMGTFMTVLLHNSPLFPLWPAS-----------FSPYPFLGATGPSQMAP-LVPAMAPDLE--------------------PTPSDHGPRRV--------------EENWETHSEEEHPFISSRSSSPLQLNLLQEEMPAPSEYADALRRG------------------------ACPDAKQLCVTGNSGSRSPPCATGELATASVQQESP---------------------------------------------------------------------------------SAAASGSS------ASSVHGSGSDYTSEVSENGQRSQD--THRDR--AFSGAAEESIWRMIERTPQCVLMTYQVPERGRDTVLREDLEKLHSMERQRPQFSSAQKEELAKVRSWIHSHPAPEERQLQRAMSPVKTEV-------------------------------------------------------QLVTLQRPVNSVQQKTPVEQL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70361-1", "uniprot_id": "PER3_MOUSE", "id": "O70361-1", "name": "Period circadian protein homolog 3", "aln": "-----------------------------------MDP--CGDPAVPGGDCPQTRGPG--------------LQGAS--------------------------GQEGPLQGTCVDSS----------------------------------------------------HSEHE---------DRNRMSEELIMVVQEMKKYFPAERHT---KPSTLDALNYALRCVHSVQANSDFFQSLGPRGAH--QADVTVYSLEDLTALASEHTSKNTDTFAAVFSFLSGRLVHISEQAALILNSKRGFLKSVHFVDLLAPQDVRAFYAHTAP-TQLPFWNNWTQRAS-QYECAPAKPFFCRICGGG-DRE-KRHYSPFRILPYLVHVHSSAQPEPE-------PCCLTLVEKIHSGYEAPRIPVDKR--IFTTTHTPGCVFLEVDERAVPLLGYLPQDLIGTSILTYLHPEDRPLMVAIHQKVLK--YAGHPPFEHSPVRFCTQNGEYVILDSSWSSFVNPWSRKVSFIIGRHKVRTSPLNEDVFATRIKKAA-SNDKDIAELQEQIHKLLLQPVHASASSGYGSLGSSGSQEQHVSITSSSESSGH-------CPEEGQHEQMTLQQVYASVNKIKNVGQQLYIESMARSSVKPVAETCVEPQGGDEQK-----DFSS-SQTLKNKSTTDTGSGGNLQQEQPSSSYQQMNCIDSVIRYLTSYSLP-ALKRKCISCTN-TSSSS---EEAKPIPEVD--SSQRDTEQLLDIRKQE--TTGPSTDIEGG--AARTLSTAALSVASGISQCSCSSTSGHAPPLQSE---------------------------------SVAVACKPWALRTKASHLAAGGFK-----------HVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQESRNRAQYSCVQ-AGSTAKHSRC---------AGSERQKHKRKKLPAPVDTSSPGAHLCPHVTGLLP-----DEQHWGPSASPSPLGAGLAFPSALVVPSQTPYLLPSFPLQDMA--------SQGVGVSAAWGAAAGCP--PLSAGPQAVAAFPSAYVDTLMTIFLHNAPLFPLWPPS-----------FSPYPSLGAAGSSELAP-LVPAMAPNPE--------------------PTTSGHSQRRV--------------EENWEAHS-EELPFISSRSSSPLQLNLLQEEMPAPSESADAVRRG------------------------AGPDAKHHCVTGPSGSRSRHCTSGELATATAQQES-----------------------------------------------------------------------------------AAASGSS------ASSIYFSSTDYASEVSENRQRPQD--RQRDE--ALPGAAEESIWRMIERTPECVLMTYQVPERGREEVLKQDLEKLQSMEQQQPLFSPAQREELAKVRSWIHSHTAPQEGHLQSCVACEDRGS-------------------------------------------------------VGDTAEVLEQHPAEDTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56645-1", "uniprot_id": "PER3_HUMAN", "id": "P56645-1", "name": "Period circadian protein homolog 3", "aln": "------------------------------------MP--RGEAPGPGRRGAKDEALG--------------EESGERW------------------------SPEFHLQRKLADSS----------------------------------------------------HSEQQ---------DRNRVSEELIMVVQEMKKYFPSERRN---KPSTLDALNYALRCVHSVQANSEFFQILSQNGAP--QADVSMYSLEELATIASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFYAHTAR-AQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGE-DRKQEKCHSPFRIIPYLIHVHHPAQPELESE-----PCCLTVVEKIHSGYEAPRIPVNKR--IFTTTHTPGCVFLEVDEKAVPLLGYLPQDLIGTSILSYLHPEDRSLMVAIHQKVLK--YAGHPPFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMN-DNDKDITELQEQIYKLLLQPVHVSVSSGYGSLGSSGSQEQLVSIASSSEASGH-------RVEETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKSSFKPVTGTRTEPNGGGECK-----TFTSFHQTLKNNS-VYTEPCEDLRNDEHSPSYQQINCIDSVIRYLKSYNIP-ALKRKCISCTNTTSSSS---EEDKQNHKADDVQALQAGLQIPAIPKSEMPTNGRSIDTGGG--APQILSTAMLSLGSGISQCGYSSTIVHVPPPETAR--------------------------------DATLFCEPWTLNMQPAPLTSEEFK-----------HVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRSKAKYSYFQ-GDSTSKQTRS---------AGCRKGKHKRKKLPEPPDSSSSNTGSGPR-RGAHQ-----NAQPCCPSAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAAT--------SPGREYAAPGTAPEGLHGLPLSEGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPS-----------FLPCPFLGATASSAISPSMSSAMSPTLD--------------------PPPSVTSQRRE--------------EEKWEAQS-EGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRN------------------------TCP-QTEYCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPS------RTGSAASGSS------DSSIYLTSSVYSSKISQNGQQSQD--VQKKE--TFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDS-------------------------------------------------------ADGAATSCGQVLVEDSC----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBM5-1", "uniprot_id": "A0A8M1PBM5_DANRE", "id": "A0A8M1PBM5-1", "name": "", "aln": "---MPGGDGFPDGEQDNSSPGPDIHTGQTDQTSSGQDPGTSGNISASGEEEEAEERIGR-------RSSGCEESGGEQT------------------------HEDVDMNSTHTSSSGNDSIHHRHHHHHRHHHHHHHHSSSNCSPGSTTGSGSTKSSKSATGSSSSSFHSTHHTECGEQTETGREHTHREMMHTVQEMKKRLPSEKRSRS-KASTVEALHYALNCVKQVQANSEYYNLLMSSGLDE-RRDATVCTLEELEGFTSEHTLKNTDSFVVVFSLASGKVVYASEQASSVLHCKRKFLESAKFVEMLYHQDVNVFYSHTAQ-PRLPSWNLGTDSAAVLFECAQVKSFFCRIRGGK-DRDGDMRYSPFRITPYLLKVQGSSG-EEE-------PCCLALAERIISGYEAPRIPMDKR--IFSTTHSPGCVFLEVDDRAVPLLGYLPQDLIGTSVLTCLHPDDRLLMLAMHRKIVK--YAGQPPFEHSPIRFRCQNGDYVTLDSSWSSFINPWSRKVAFIIGRHKVRTGPLNEDVFAARSKADQPVTCEDVKELQAMIHKLFLQPVHNNGSSGYGSLGSNGSHEHYISVASSSDSNGN-------LWEDSHRETMTLQQFCADVNKVKNWGQQAYLESRKK---LTALGPATAVAGAG--------VHASSSHDLGIRD-HLKQSLQKARKQPHIPSYQQINCVDSIIRYLESCATS-ALKRKCESLSITTSSSSSTSEEDKPTSAAHENTDEAALDAARALDSQVSAGSATTAAVVGAPLTDITISTEAMSVVSVTSQCSYSSTIVHVPQPESEVTA----------------LEDAPMG---SEPADSAPAPASPAPDSGSASTSQEELL-----------VLGLTKEVLSAHTQKEEQQFVDRFRHRILQSPYSSYLQQDN-------------SSNAHSHH---------RGDVVRQPNKHKRPKPEDSSDSYECSQPGNYWSLPGPTAAPHSSWPSSESSQPPPSNIGFVPPMAVPMQTP---PYFNIIGAD--------QQPVMLQPDPGVQNLQPMTPMMVVLLP--SFPMYPPNNGMYFPMAAPGVVPYNIGG-----------FVPPGAPMPAEAPLQGHNLESAGVGVPA--------------------EPDSIPEPWFG--------------EDLDAAQP--TALFSSSRSSSPIQLNLLQEELTKPSEAQTSTNADSL----------------------QEPHTKTDDARSECGHQDAHSSSSEMLDQLLQEDARSGTGSNASGSGSGESGG---------------------------------------------SLGSGSGLGSN------GTSTSHTGSS------NSSKYFASND-SSDTSRKARKSAE--AQERERSGFKKHVDDPLWSMIKQTPEPVMLTYQISSRDQAQVLQEDREKLILMQPMQPWFTSDQKKELAEVHPWIQQNTVPQEINTQGCVSCNTIEPNK-------------------------------------------------KLNLQTDSPNPPDISCPQDCPPQENRPDTDT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z301-1", "uniprot_id": "PER2_RAT", "id": "Q9Z301-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYVDFSP----SPTSPTQEPGEPQPTQ--------AVLQEDVDMSS--------GSSG----------NENCSTGRDSQGSDCDDSG----KELRMLVES------SNTH----PSPDDTFRLMMTEAEH-NPSTSGCSSEQS---------AKADAHKELIRTLRELKVHLPADKKAKG-KASTLATLKYALRSVKQVKANEEYYQLLMSSESQPCSVDVPSYTMEQVEGITSEYIVKNSDMFAVAVSLVSGKILYISNQVAPIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTP-YKLPPWSVSSGLDSFTQECMEEKSFFCRVSVGK-HHENEIRYQPFRMTPYLVKVQEQKGAASQ-------LCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQDVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ--ASGQP-FDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAASPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------QEESHWRRSGIFKTSGKSQSKSHFSPESG----GQKEASVAEMQSSPPAQVRS----------VTTMERDSSGASLPKASFPEELTYKSQPPCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANIPS------RKATVSPGLHSGEAARSSKVTS-------------HTEVSAHLSSLALPGKAESVVSLTSQCSYSSTIVHVGDKKPQPE--------------LETVEDVAS-------GPESQDDAAG-----GLSQEKGSLQ-----------KLGLTKEVLAAHTQREEQGFLQRFREVSRLGALQAHCQNYLQERSRAPASDR---GLRNASG----IESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRP--------PLVGLNATAWSPSDTSQSSCPSAPFPAPVP-AYPLPVFPAPGIVSTPGTVVAPPAAAHTGFTMPVVPMGTQPEFAVQPLPFAAPLA-PVMAFMLPSYPFPPATPNLPQAFFPS-QPHFPAHPTLASEITPASQAEFPSRTSMLRQ--------------------PCACPVTPPAG--------------TVALG---RASPPLFQSRGSSPLQLNLLQLEEAPESSTGAAGTLG---TTGTAASGLDCTSGASRDRQPKAPPTCSE--PSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSD---------------------------------------------SLGSSSLGCDT-----SRSGAGSSDTS------HTSKYFGSIDSSENNHKAKMITD----TEESEQFIKYVLQDPIWLLMANTDDNIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPHFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESE-------------------------------------------EKGNLCLPYEEDSPSLGLCDTSEAKEEESGQLANPRKEAQT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54943-1", "uniprot_id": "PER2_MOUSE", "id": "O54943-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYVDFSP----SPTSPTKEPGAPQPTQ--------AVLQEDVDMSS--------GSSG----------NENCSTGRDSQGSDCDDNG----KELRMLVES------SNTH----PSPDDAFRLMMTEAEH-NPSTSGCSSEQS---------AKADAHKELIRTLKELKVHLPADKKAKG-KASTLATLKYALRSVKQVKANEEYYQLLMSSESQPCSVDVPSYSMEQVEGITSEYIVKNADMFAVAVSLVSGKILYISNQVASIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTP-YKLPPWSVCSGLDSFTQECMEEKSFFCRVSVGK-HHENEIRYQPFRMTPYLVKVQEQQGAESQ-------LCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQAVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ--AGGQP-FDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAPPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------QEESHRRRSGIFKTSGKIQTKSHVSHESG----GQKEASVAEMQSSPPAQVKA----------VTTIERDSSGASLPKASFPEELAYKNQPPCSYQQISCLDSVIRYLESCSEAATLKRKCEFPANIPS------RKATVSPGLHSGEAARPSKVTS-------------HTEVSAHLSSLTLPGKAESVVSLTSQCSYSSTIVHVGDKKPQPE--------------LETVEDMAS-------GPESLDGAAG-----GLSQEKGPLQ-----------KLGLTKEVLAAHTQKEEQGFLQRFREVSRLSALQAHCQNYLQERSRAQASDR---GLRNTSG----LESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRP--------PLMGLNATAWSPSDTSQSSCPSAPFPTAVP-AYPLPVFQAPGIVSTPGTVVAPPAATHTGFTMPVVPMGTQPEFAVQPLPFAAPLA-PVMAFMLPSYPFPPATPNLPQAFLPS-QPHFPAHPTLASEITPASQAEFPSRTSTLRQ--------------------PCACPVTPPAG--------------TVALG---RASPPLFQSRGSSPLQLNLLQLEEAPEGSTGAAGTLG---TTGTAASGLDCTSGTSRDRQPKAPPTCNE--PSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSD---------------------------------------------SLGSSSLGFGT-----SQSGAGSSDTS------HTSKYFGSIDSSENNHKAKMIPD----TEESEQFIKYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESE-------------------------------------------EKGNICLPYEEDSPSPGLCDTSEAKEEEGEQLTGPRIEAQT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15055-1", "uniprot_id": "PER2_HUMAN", "id": "O15055-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYAEFPP----SPSNPTKEPVEPQPSQ--------VPLQEDVDMSS--------GSSGH-------ETNENCSTGRDSQGSDCDDSG----KELGMLVEP------PDAR----QSPD-TFSLMMAKSEH-NPSTSGCSSDQS---------SKVDTHKELIKTLKELKVHLPADKKAKG-KASTLATLKYALRSVKQVKANEEYYQLLMSSEGHPCGADVPSYTVEEMESVTSEHIVKNADMFAVAVSLVSGKILYISDQVASIFHCKRDAFSDAKFVEFLAPHDVGVFHSFTSP-YKLPLWSMCSGADSFTQECMEEKSFFCRVSVRK-SHENEIRYHPFRMTPYLVKVRDQQGAESQ-------LCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQDVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ--SGGQP-FDYSPIRFRARNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAHPCTEEKALHPSIQELTEQIHRLLLQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------HEDSRRRRAEICKNGNKTKNRSHYSHESG----EQKKKSVTEMQTNPPAEKKA----------VPAMEKDSLG-----VSFPEELACKNQPTCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANVPALRSSDKRKATVSPGPHAGEAEPPSRVNS-------------RTGVGTHLTSLALPGKAESVASLTSQCSYSSTIVHVGDKKPQPE--------------LEMVEDAAS-------GPESLDCLAGPALACGLSQEKEPFK-----------KLGLTKEVLAAHTQKEEQSFLQKFKEIRKLSIFQSHCHYYLQERSKGQPSERTAPGLRNTSG----IDSPWKKTGKNRKLKSKRVKPRDSSESTGSGGPVSARP--------PLVGLNATAWSPSDTSQSSCPAVPFPAPVPAAYSLPVFPAP------GTVAAPPAPPHASFTVPAVPVDLQHQFAVQPPPFPAPLA-PVMAFMLPSYSFPSGTPNLPQAFFPS-QPQFPSHPTLTSEMASASQPEFPSRTSIPRQ--------------------PCACPATRATP--------------PSAMG---RASPPLFQSRSSSPLQLNLLQLEEAPEGGTGAMGTTG---ATETAAVGADCKPGTSRDQQPKAPLTRDE--PSDTQNSDALSTSSGLLNLLLNEDLCSASG--------SAASE---------------------------------------------SLGSGSLGCDA-----SPSGAGSSDTS------HTSKYFGSIDSSENNHKAKMNTG----MEESEHFIKCVLQDPIWLLMADADSSVMMTYQLPSRNLEAVLKEDREKLKLLQKLQPRFTESQKQELREVHQWMQTGGLPAAIDVAECVYCENK-------------------------------------------EKGNICIPYEEDIPSLGLSEVSDTKEDENGSPLNHRIEEQT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFB2-1", "uniprot_id": "A0A8M9QFB2_DANRE", "id": "A0A8M9QFB2-1", "name": "Period circadian protein homolog 2", "aln": "MSEDLDSKPYLFSSLEGQDGAIGCSSMATLHRMASFAEGTELGLASEGSDSSQDRPTSGHNTRKMSHSLHEDVEMKSSS------GSSGSGTESHGNESHGNESHGNESHGNESSGSSNSRSKDSALLVSSG-SNKSSNSHSPSPPSSTNAFSLLSASSEQDNPSTSGCSSEES---------AKAKTQKELIKTLKELKLHLPAEKRNKGSKSTTLNTLKYALRCVRQVEANEEYYQLLMINDSQPSGLDVSSYTIEEIDSITSEYTLKNTDIFAVAVSLITGKIVYISDQAASILNCKRDVFKNAKFVEFLTPQDVSVFYSFTTP-YRLPSWSMCTGADSSPSDCMQEKSFFCRISGGK-ECEADLQYYPFRMTPYLMKVQDMEHSEDQ-------FCCLLLAERVHSGYEAPRIPTDKR--IFTTTHTPSCVFQDVDERAVPLLGYLPQDLIGTPVLLHLHPNDRPTMLGIHRKILQ--CAGQP-FDHS-IRFCARNGEYITIDTSWSSFVNPWSRKVSFVIGRHKVRMGPVNEDVFAAPATAEGKCVDSDIQDITEQIHRLLLQPVHNNGSSGYGSLGSN---DHLLSVASSSESNGNGTRQRHEEEDIRKAKPRSFQEICKGVHMQKNQEL----QSKKSPTKFVQKSPVVRPKD----------SAYPVNWRESQEEQRAAVQEELAFKDQTVYSYQQISCLDSVIRYLESCNVPITVKRKCQSSSNTTSSNSDEDKQRNADSSMQVSEEPAHLKEQSGLSTLEVSKKPPGSGVVSPSLTPLALPSKPESVVSITSQCSYSSTIVHVGDKKVVSSTRHISTKQEYSSKLQKIIEDVPSA-----EGTDVQGLAVPPAAVSPQNQEREAYK-----------KLGLTKQVLAAHTQKEEQAFLSRFRELRGVHAFKADCSLYLERQKGQVTSEAVPAARSCKAGGGGAQETTTTRRGRNKKTKSKRVKPNESSDSTPSGRRPAHRP--------QLQGLNQTSWSPSDTSQSTFP-IAYPAVMP-AYPLQMYPGA------GGMQPRVDAPMPGFGEGQCTPDPRIPMQPIQTPYSAPLVTPMVALVLPNYMFPQVGSAPRQAFYPPKQGPFPTQPTFQTQPGFTPQASFPPQTTFTIQTQFTSQNPFSSQPTFQPQPFPFACPEDPPKAPEPELREEQSRSPTPQSMGGGGPPSPPLFQSRCSSPLQLNLLQLEETQRSADRQENTAPSAVPLNNCSAGVEKAGSVTGQSKPVKDVVQDEGSPVDGQHSDALSSSSDLLDILP-EDSRSGTG--------SATSG---------------------------------------------SMGSGSNRCGT-----SASGGSASRTESSNKSNNSSNYFGSVDSSQKSHKAKAQGSGVLALDGSENLIKYVLQDPLWLLMANVDEDVMMSYQLPSRDIQKVLREDREKLRQMQKSQPRFTDEQKRELADVHPWMRRGGLPKAIDIKACMGCEELSEAL------------------------------------NEDDPPDLHMGEAENSDVTAAPNSQELQEPPN-SPTHSCPGPDT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CHI5-1", "uniprot_id": "PER1_RAT", "id": "Q8CHI5-1", "name": "Period circadian protein homolog 1", "aln": "----------MSGPLEGADGGG------DPRPGEPFCPGGVPSPGAPQHRPCPGPS------------LADDTDANSNG-------SSGNE-------SNGHESRG-ASQRSSHSSSSGN-GKDSAL-LETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQS---------ARARTQKELMTALRELKLRLPPERRGKG-RSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCAMDMSTYTLEELEHITSEYTLRNQDTFSVAVSFLTGRIVYISEQAGVLLRCKRDVFRGARFSELLAPQDVGVFYGSTTP-SRLPTWGTGTSAGSGLKDFTQEKSVFCRIRGGP-DRDPGPRYQPFRLTPYVTKIRVSDGAPAQ-------PCCLLIAERIHSGYEAPRIPPDKR--IFTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQ--LAGQP-FDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPVPSPAPSLDSDIQELSEQIHRLLLQPVHSSSTTGLCGVGPLMSPGPLHSPGSSSDSNGG-----DAEGPG-PPAPVTFQQICKDVHLVKHQGQQLFIESRAKPPPRPRLLATGTFKA--KVLPCQSPNPELEVAPAPDQASLALAPEEPERKESSGCSYQQINCLDSILRYLESCNIPNTTKRKCASSS-CTASSASDDDKQRAGPVPVGAKKDTSSAVLSG-----EGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESD-------------IIMMED-------LPGLAPGPAPSPAPSPTVAPDPAPDAYR-----------PVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDTSSVA-----PSAPG---CHHGPIPSGR---------RHHCRSKAKRSR--HHQTPRPET-----------------------PCYVSHPS-PVPSSGPWPPPPATTP--FPAVVQPYP-------LPVFSPRGGPQPLPPAPTSVSP--------ATFPSPLVTPMVALVLPNYLFPSP----------------TSYPYGVSQAPVEGP---PTPASHSPS---------------------PSLPPPPPSP--------------PHR------PDSPLFNSRCSSPLQLNLLQLEESPRTEGGAAAG---------GPGSSAGPLPPSEE---SAEPEPRLVEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGS---------------------------------------------GSGSGSHEGGS----TSASITRSSQSS------HTSKYFGSIDSSEAEAGAAQART----EPG-DQVIKYVLQDPIWLLMANADQHVMMTYQVPSRDAASVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPQALDVTACVDCGSSVQDP-GHSDDPLFSELDGLGLEPMEEGGGEGGGVGGGGGGVGGGGGDGGEEAQTQIGTKGSSSQDSAMEEEEQGGSSSSPALPAEENGTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35973-1", "uniprot_id": "PER1_MOUSE", "id": "O35973-1", "name": "Period circadian protein homolog 1", "aln": "----------MSGPLEGADGGG------DPRPGEPFCPGGVPSPGAPQHRPCPGPS------------LADDTDANSNG-------SSGNE-------SNGPESRG-ASQRSSHSSSSGN-GKDSAL-LETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQS---------ARARTQKELMTALRELKLRLPPERRGKG-RSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCAMDMSTYTLEELEHITSEYTLRNQDTFSVAVSFLTGRIVYISEQAGVLLRCKRDVFRGARFSELLAPQDVGVFYGSTTP-SRLPTWGTGTSAGSGLKDFTQEKSVFCRIRGGP-DRDPGPRYQPFRLTPYVTKIRVSDGAPAQ-------PCCLLIAERIHSGYEAPRIPPDKR--IFTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQ--LAGQP-FDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAPSLDSDIQELSEQIHRLLLQPVHSSSPTGLCGVGPLMSPGPLHSPGSSSDSNGG-----DAEGPG-PPAPVTFQQICKDVHLVKHQGQQLFIESRAKPPPRPRLLATGTFKA--KVLPCQSPNPELEVAPVPDQASLALAPEEPERKETSGCSYQQINCLDSILRYLESCNIPSTTKRKCASSSSYTASSASDDDKQRAGPVPVGAKKDPSSAMLSG-----EGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESD-------------IIMMED-------LPGLAPGPAPSPAPSPTVAPDPTPDAYR-----------PVGLTKAVLSLHTQKEEQAFLNRFRDLGRLRGLDTSSVA-----PSAPG---CHHGPIPPGR---------RHHCRSKAKRSRHHHHQTPRPET-----------------------PCYVSHPS-PVPSSGPWPPPPATTP--FPAMVQPYP-------LPVFSPRGGPQPLPPAPTSVSP--------ATFPSPLVTPMVALVLPNYLFPTP----------------PSYPYGVSQAPVEGP---PTPASHSPS---------------------PSLPPPPLSP--------------PHR------PDSPLFNSRCSSPLQLNLLQLEESPRTEGGAAAG---------GPGSSAGPLPPSEE---TAEPEARLVEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGS---------------------------------------------GSGSGSHEGGS----TSASITRSSQSS------HTSKYFGSIDSSEAEAGAARART----EPG-DQVIKCVLQDPIWLLMANADQRVMMTYQVPSRDAASVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVTACVDCGSSVQDP-GHSDDPLFSELDGLGLEPMEEGGGEGGGCG-----VGGGGGDGGEEAQTQIGAKGSSSQDSAMEEEEQGGGSSSPALPAEENSTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15534-1", "uniprot_id": "PER1_HUMAN", "id": "O15534-1", "name": "Period circadian protein homolog 1", "aln": "----------MSGPLEGADGGG------DPRPGESFCPGGVPSPGPPQHRPCPGPS------------LADDTDANSNG-------SSGNE-------SNGHESRG-ASQRSSHSSSSGN-GKDSAL-LETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQS---------ARARTQKELMTALRELKLRLPPERRGKG-RSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCSMDMSTYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQDVGVFYGSTAP-SRLPTWGTGASAGSGLRDFTQEKSVFCRIRGGP-DRDPGPRYQPFRLTPYVTKIRVSDGAPAQ-------PCCLLIAERIHSGYEAPRIPPDKR--IFTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQ--LAGQP-FDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGG-----DAEGPG-PPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKA--KALPCQSPDPELEAGSAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSG-----EGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESD-------------IIMMED-------LPGLAPGPAPSPAPSPTVAPDPAPDAYR-----------PVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTA-----PSALGERGCHHGPAPPSR---------RHHCRSKAKRSR--HHQNPRAEA-----------------------PCYVSHPS-PVPPSTPWPTPPATTP--FPAVVQPYP-------LPVFSPRGGPQPLPPAPTSVPP--------AAFPAPLVTPMVALVLPNYLFPTP----------------SSYPYGALQTPAEGP---PTPASHSPS---------------------PSLPALAPSP--------------PHR------PDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAG---------GPGSSAGPPPPSAE---AAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGS---------------------------------------------GSGSGSHEGGS----TSASITRSSQSS------HTSKYFGSIDSSEAEAGAARGGA----EPG-DQVIKYVLQDPIWLLMANADQRVMMTYQVPSRDMTSVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVMACVDCGSSTQDP-GHPDDPLFSELDGLGLEPMEEGGGEQGSSGG-----GSGEGEGCEEAQG--GAKASSSQDLAMEEEEEGRSSSSPALPTAGNCTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PH02-1", "uniprot_id": "A0A8M1PH02_DANRE", "id": "A0A8M1PH02-1", "name": "", "aln": "----MSDDNSDSAPSNDADSGAGG---IEKKAGRSCGMSESSPSSNPESSGSGGLSGPKGSAGGNRGVNSDDTDGLSSGNDSGERESEGGM-------QRGSGSRGRQSNRSYQSSSSQN-GKDSAMGMETTESNKSSNSHSPSPPSSSLAYSLLSASSEQDPPSTSGCSSDQS---------ARVQTQKELMRALNELKIRLPPERKMKG-RSSTLNALKYALSCVRQVRANQEYYHQWNVEECHGCSLDLSTFTVEELDNITSEYTLKNTDTFTMAVSFLSGKVVYISPQGSSLLRSKPERLHGVLFSELLAPQDVSTFYSNTAP-CKLPAWASCIGSVSPPMECTQEKSMFCRISGDV-SSSSDVRYYPFRLTPYLLTLRDSDMAFPQ-------PCCLLIAERVHSGYEAPRIPLDKR--IFTTSHTPSCVFQEVDERAVPLLGYLPQDLVGTPVLLCIHPDDRHIMVAIHKKILQ--FAGQP-FEHSPLRMCARNGEYMTIDTSWSSFINPWSRKVAFIVGRHKVRTSPLNEDVFTPPRGLEERALTPDIVQLSEQIHRLLVQPVHCGSSQGYGSLPSNGSHEHQPSAASSSDSSGP-----GVEDPSQLHKPMTFQQICKDVHMVKTSGQQVFIDSRNRPPPK-KHSTAGALKAGESAEVCRSLIP-CAAPPSKSSAPSLIVQKEP----PTTFSYQQINCLDSIIRYLESCNVPNTVKRKCGSSS-CTASSTSDDDKQQEAP---GNAKGPSVSLVDD-----SALLP-----------PLALHNKAESVASVTSQCSFSSTIVHVGDKKPPESD-------------IVMEEAPPTPNIALPVTQPQVPPMATPSLPLSPAPDRDAGRRGGPGASAGGERLGLTKEVLSAHTQQEEQNFMCRFGDLSKLRVFDPTSAVRR--RPNAPLSRGVRCSRDYPAA---------GSSGRRRGRGGKRLKHQESSEQTGSCSPAGPIRGLLP--GVPALGRPSNPSIPMGPTASSSSWPTSGSQAS--VPNVQYPPT-------VLPFYPVYPPISHPVSDPSMQSGLRFPLQNSQMAPPMVPPMMALVLPNYMFPQPSVGMAQPFFSP----NSAFPFAAANMGSPAPCQIQTPIQRAHS---------------------RSSTPHSYSQ--------------RENGAEREGAESPLFQSRCSSP--LNLLQLEESPSNRFEVASGQQTT-SPMVGQGGGAGGQASSNQRGSAVDSKTNENGETNESNQDAMSTSSDLLDLLLQEDSRSGTGSAASGSGSSGTGSS--------------------------------------------GSGSGSSGSGSNGCSSSGSGTRSSQSS------NTSKYFGSVDSSENSHSRKQTAE----GDGEAQFIKCVLQDPIWLLMANTDEKTMMTYQLPIRDRDSVLKEDRAALRAMQKHQPRFTEEQKSELSQVHPWIRTGRLPRAINISACAGCRSPPSVPSATPFDVEIHEMEFCSVLAVAEEKQTPADTVMEKS-ETDGQNETCKENNGTVTTAQINDQEMLTEEQEMTSQIEEEMGASHTQMTH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07663-1", "uniprot_id": "PER_DROME", "id": "P07663-1", "name": "Period circadian protein", "aln": "--MEGGESTESTHNTKVSDSAYSNSCSNSQSQRSGSSKSRLSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKK--------------------NKGAGQGAGQAQTLISASTSLEGRDEEKPRPSG---TGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQS----------GSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAP-TCKLKISEEAQSRNTRIKEDIVKRLAETVSRPSDTVKQEVSRRCQALAS---------------------FMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYD-------------------SKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSSVTN---------TSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG-------------------------------NGTNSGTGTGTASSSKGGSAAIP-----------PVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPGHGIKRGGSHS---------WEGEANKPKQQLTLGTDAIKGAAGSAGGAVGTG-----------GVGSGGAGVAGGGGSGTGVAGTPEGRATTTSGTGTPGG-----------AGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVH----------------STHTAMAQSSFSSAGLFPTFYYIPAS----------------------LTPTSPTRS-----------------------PRMHKHPHKGGTDMPTTSQQAAAAAAQAMPLQYMAG----------------------------VMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPERPLGSQSAYN--------------------------------------------------------------KSVYTTTPAS------MTKKVPGAFHSVTTPAQVQRPSSQ----------SASVKTEPGSSAAVSDPCKKEVPDSSPIPSVMGDYNSDPPCSSSNPANNKKYTDSNGNSDDMDGSSFSSFYSSFIKTTDGSESPPDTEKDP-----------------------------------------------KHRKLKSMSTSESKIMEHPEEDQTQHGDG----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . : : : : : . . . :: . : . :. : : .. : * * ..*: * ::: : . :: . * ::: :* .* . : :. : : : ***: . : . : *.*:.* .:: *: *:. :: **. *.. **:*****: .:: * .* * :..::: . . * . *: :** *: :::.*:.*::*****: *::*:*:* .* : :** . . . * . ::: : . : . . . : : . : : . . . : .* : . . : . :.* . : ** :* *.:. *: : :. . : . . . : : . . : .: . * . :. : : :. :. . :. :. . . ..* . :: : . . . . ", "identical_positions": 57, "similar_positions": 181, "identity": "3.56%" }, { "cls_id": "homologset.agr.FB:FBgn0003071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30835-1", "uniprot_id": "PFKAL_RAT", "id": "P30835-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVDLEKLRMSG-----------AGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGG-ENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLSIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE-APPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRVLSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLRGRSFENNWKIYKLLAHQKVSKE--KSNFS------LAILNVGAPAAGMNAAVRSAVRTGISEGHTVYVVHDGFEGLAK-GQVQEVGWHDVAGWLGRGGSMLGTKR-TLPKPHLEAIVENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGT---------------------------------------------------DFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRG----LVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWMS--------------EKLRD-VYRKGRVFAN---APDSACVIGLRKKVVAFSSVTELKK-ETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12382-1", "uniprot_id": "PFKAL_MOUSE", "id": "P12382-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVDLEKLRMSG-----------AGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGG-ENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE-APPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWKIYKLLAHQKVSKE--KSNFS------LAILNVGAPAAGMNAAVRSAVRTGISEGHTVYIVHDGFEGLAK-GQVQEVGWHDVAGWLGRGGSMLGTKR-TLPKPHLEAIVENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGT---------------------------------------------------DFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRG----LVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWVS--------------EKLRD-VYRKGRVFAN---APDSACVIGLRKKVVAFSPVTELKK-ETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17858-1", "uniprot_id": "PFKAL_HUMAN", "id": "P17858-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAVDLEKLRASG-----------AGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGG-ENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE-APPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKE--KSNFS------LAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAK-GQVQEVGWHDVAGWLGRGGSMLGTKR-TLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGT---------------------------------------------------DFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRG----LVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLS--------------EKLRE-VYRKGRVFAN---APDSACVIGLKKKAVAFSPVTELKK-DTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47857-1", "uniprot_id": "PFKAM_MOUSE", "id": "P47857-1", "name": "ATP-dependent 6-phosphofructokinase, muscle type", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHEEHHAAKTLG-----------IGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGG-EHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLNDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPE-CPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWEVYKLLAHVRPPVSKGGLHT-------VAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAK-GQIEEAGWSYVGGWTGQGGSKLGTKR-TLPKKNLEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGS---------------------------------------------------DFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNVEHLVQKMKTTVKRG----LVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMS--------------GKIKE-SYRNGRIFAN---TPDSGCVLGMRKRALVFQPVTELKD-QTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHISRKRSGEAAV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47858-1", "uniprot_id": "PFKAM_RAT", "id": "P47858-1", "name": "ATP-dependent 6-phosphofructokinase, muscle type", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHEEHHEAKTLG-----------IGKAIAVLTSGGDAQGMNATVRAVVRVGIFTGLRVFFVHEGYQGLVDGG-EHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLNDLQKDGKITAEERTKSSYLNIVFLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPE-CPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNTAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWEVYKLLAHVRPPVSKGGLHT-------VAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAK-GQIEEAGWSYVGGWTGQGGSKLGTKR-TLPKKNLEQISANITKYNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGS---------------------------------------------------DFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNVEHLVQKMKTTVKRG----LVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGNPTPFDRNFATKMGAKATNWMS--------------GKIKE-SYRNGRIFAN---TPDSGCVLGMRKRALVFQPVTELKD-QTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHISRKRSGEAAV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08237-1", "uniprot_id": "PFKAM_HUMAN", "id": "P08237-1", "name": "ATP-dependent 6-phosphofructokinase, muscle type", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHEEHHAAKTLG-----------IGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGG-DHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPE-CPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHT-------VAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAK-GQIEEAGWSYVGGWTGQGGSKLGTKR-TLPKKSFEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGS---------------------------------------------------DFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHLVQKMKTTVKRG----LVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMS--------------GKIKE-SYRNGRIFAN---TPDSGCVLGMRKRALVFQPVAELKD-QTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRKRSGEAAV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7I7-1", "uniprot_id": "A0AB13A7I7_DANRE", "id": "A0AB13A7I7-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "------------------------------------------------------------------METVWDNCVCVCQLCVCVWDVFVCVCQISVCLLELCVCLLRLSVLLFHWIPHIGLTVWIWQRTHRKTQFDANHVYGSKDPSYCDESKTEVLADGKTTSTTCFDSGLDDLSCSSATHNSCRLFEMQHSAPVDPTKMG-----------VGRAIAVLTSGGDAQGMNAAVRATVRVGIYTGAKVYFVHEGYQGLVDGG-DNIRQATWESVSMMLQLGGTVIGSARCQDFRTKEGRAKAACNLVKLGITNLCVIGGDGSLTGANEFRNEWSELLQILQKTGKITAEEAKCSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEVVDAITTTAQSHQRAFILEVMGRHCGYLALVTALSCGADWVFIPE-MPPDEGWEDHLCRRLTYQRSIGNRLNVIIVAEGALDRHGKPITCDIIKNLVTKKLGFDTRATILGHVQRGGTPSAFDRILGSRMGVEAVMALLEATPDTPACVVSLSGNMAVRLPLMECVQVTKEVTKAMAEGRFEEAIKLRGKSFENNWNTYKLLAHVTAPDVKSNIN--------IAILNVGAPCAGMNAAVRSAVRIGILQGHNMLAVHDGFEGLAN-GTIEPMAWGYVGGWTGKGGSILGTKR-SLPANMIEEISLNIAKFNIHALVIIGGFEAFVGGLELVTAREKYEELCIPLVVIPATVSNNVPGS---------------------------------------------------DFSVGADTALNTITTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYVFEDPFGIHDLEANVEHLLEKMKTTVKRG----LILRNEKCNANYTTDFLFNLYSEEGKGVFDCRKNVLGHMQQGGTPTPFDRNFGTKMGAKAVLWLT--------------DKLKE-CYRHGRIFAN---TPDSACVLGMRKRAMLFQPLSDLKE-DTDFEHRIPKTEWWLKLRPILKILAKYKISLDTSETATMEHVIKKRGGV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WUA3-1", "uniprot_id": "PFKAP_MOUSE", "id": "Q9WUA3-1", "name": "ATP-dependent 6-phosphofructokinase, platelet type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDLDSSSSS-AYPKYLEHLSG-----------DGKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGG-SNIVEAKWDCVSSILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPE-SPPEEDWEENMCLKLSENRARKKRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLRGRRFEGNLNTYKRLAIKLPDEKIVKSNCN------VAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAIYDGFEGFAN-GQIKEIGWADVGGWTGQGGSILGTKR-TLPGKYLEKIAEQMHSHSINALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPATVSNNVPGS---------------------------------------------------DFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNVVHLTEKMKTSIQRG----LVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWIS--------------AKLKG-SQGTGKKFV----SDDSICVLGICKRDLLFQPVAELKK-VTDFEHRIPKEQWWLKLRPIMKILAKYEASYDMSDSGKLESLQHHEEL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47860-1", "uniprot_id": "PFKAP_RAT", "id": "P47860-1", "name": "ATP-dependent 6-phosphofructokinase, platelet type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDQDSSTSSTSFPKYLEHLSG-----------DGKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGMVDGG-SNIVEAKWECVSSILQVGGTIIGSARCQAFRSREGRLKAACNLVRLGITNLCVIGGDGSLTGANLFRKEWSGLLEELAKNGEIDSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPE-SPPEEGWEEEMCLKLSENRARKKRLNIIIVSEGAIDTQNKPITSEKIKELVVTNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLRGRSFEGNLNTYKRLAIKEPDDKIPKSNCN------VAIINVGAPAAGMNAAVRSAVRVGIAEGHKMFAIYDGFDGLAN-GQIKEIGWGDVGGWTGQGGSILGTKR-TLPGKYLEKIAEQMHSKNINALLIIGGFEAYLGLLELAAARNKHEAFCVPMVMVPATVSNNVPGS---------------------------------------------------DFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEQFDIRDLQSNVMHLTEKMKTSIQRG----LVLRNENCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWIS--------------AKLKG-SHGTGKKFV----SDDSICVLGIQKRDLLFKPVAELRK-ATDFEHRIPKQQWWLKLRPIMKILAKYEASYDMSDVGKLEPVHNHGELSAI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01813-1", "uniprot_id": "PFKAP_HUMAN", "id": "Q01813-1", "name": "ATP-dependent 6-phosphofructokinase, platelet type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDADDSRAPKGSLRKFLEHLSG-----------AGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGG-SNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPE-SPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCN------VAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAK-GQIKEIGWTDVGGWTGQGGSILGTKR-VLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGS---------------------------------------------------DFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRG----LVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWIT--------------AKLKE-ARGRGKKFT----TDDSICVLGISKRNVIFQPVAELKK-QTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQPWSV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIC1-1", "uniprot_id": "A0AB32TIC1_DANRE", "id": "A0AB32TIC1-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQSDN-------KRFFENLTG-----------AGKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFVHEGYQGMVDGG-DNIKEATWENVSSMLQVGGTVIGSARCKDFRTHEGRLKAAHNLIQRGITNLCVIGGDGSLTGANLFREEWSGLLAELVQQGLIDEDAAQKYSALHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVLIPE-MPPEDGWEEKMCQKLSAKRAGMKRLNIIIVAEGAIDRKNQPITSEHVKNLVVSRLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLETTANTPACVVSLCGNQSVRLPLMECVQMTQEVQKAMDGKRFEEAVQLRGRSFENNLKTYKLLAHRKPESELPHSNFN------VAVLNVGAPAAGMNAAVRSAVRVGISEGHKMFAVNDGFEGFYK-GQIKEIKWADVGGWTGQGGSLLGTKR-TLPAKHIDKIAEQMRKYNINALLVIGGFEAYLGIMELLEARRTYEELCVPMVMVPATVSNNVPGSDLSIGADTALNAITAALECLLQLNEARAKYEEFCIPLCMLPATISNNVPGTDLSIGADTALNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLAAGADAAYIFEEPFDIRDLQANVEHLTEKMKTSIQRG----LVLRNENSNENYTTDFIYQLYTEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMQWIT--------------KKLNE-SYRRGRVFAN---TEDSACLLGMRRRAMVFQPVVQLKD-ETDFVHRIPKEQWWLKLRPLMKILAKYKTSYDVSDSGQLEHVVVNRPKASETSVTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THG1-1", "uniprot_id": "A0AB32THG1_DANRE", "id": "A0AB32THG1-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDT-------KKYIENLSG-----------AGKCIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIHEGYQGMVDGG-DNIKEASWESVSSMLQVGGTVIGSARCKDFRTHEGRLHAALNLVQRGITNLCVIGGDGSLTGANLFREEWSGLLDELVQSGQISEDAAQTHSALHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVLIPE-RPPKDGWEEQMCQKLSENRADKKRLNIIIVAEGAIDQNNKPITTDHIKDLVVSRLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEASPGTPACVVSLCGNQAVRVPLMECVQMTQEVQKAMDEKRFEEAVKLRGRSFENNLNTYKLLSHRKIDTELPHSSFN------VAVLNVGAPAAGMNAAVRSAVRVGITEGHTMFAVSDGFEGFYK-GQIKEIKWGDVGGWTGQGGSLLGTKR-TLPAKHVDKIAEQMRIHNINALLVIGGFEAYLGLMELQAARSKHAELCVPMVMVPATVSNNIPGSDLSIGADTAINAITDAFESLLQLVDARSRYEEFCVPLCMLPATISNNVSGTDLSIGADTSLNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLAAGADAAYIYEEPFDIRDLQSNVEHLTEKMKTSIQRG----LVLRNENSNENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKIAAKAMQWIS--------------KKLKE-FYRDGRVFAN---TEDSACLLGMRRRALLFQPVVQLKD-ETDFVHRIPKEQWWLRLRPLMKILAKYKTSYDVSDSGQLEHIVRLRAKDSSAI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52034-1", "uniprot_id": "PFKA_DROME", "id": "P52034-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSEINQRFLARGSQ-----------KDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGG-DCIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPE-MPPKVDWPDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIA-GNVRELGWSDVSGWVGQGGAYLGTKR-TLPEGKFKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGT---------------------------------------------------EFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRG----LILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLA--------------AQIKANIDANGVVNCK---SPDTATLLGIVSRQYRFSPLVDLIA-ETNFDQRIPKKQWWLRLRPLLRILAKHDSAYEE--EGMYITVEEECDTDAVA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16861-1", "uniprot_id": "PFKA1_YEAST", "id": "P16861-1", "name": "ATP-dependent 6-phosphofructokinase subunit alpha", "aln": "-MQSQDSCYGVAFRSIITNDEALFKKTIHFYHTLGFATVKDFNKFKHGENSLLSSGTSQDSLREVWLESFKLSEVDASGFRIPQQEATNKAQSQGALLKIRLVMSAPIDETFDTNETATITYFSTDLNKIVEKFPKQAEKLSDTLVFLKDPMGNNITFSGLANATDSAPTSKDAFLEATSEDEIISRASSDASDLLRQTLGS---------SQKKKKIAVMTSGGDSPGMNAAVRAVVRTGIHFGCDVFAVYEGYEGLLRGG-KYLKKMAWEDVRGWLSEGGTLIGTARSMEFRKREGRRQAAGNLISQGIDALVVCGGDGSLTGADLFRHEWPSLVDELVAEGRFTKEEVAPYKNLSIVGLVGSIDNDMSGTDSTIGAYSALERICEMVDYIDATAKSHSRAFVVEVMGRHCGWLALMAGIATGADYIFIPERAVPHGKWQDELKEVCQRHRSKGRRNNTIIVAEGALDDQLNPVTANDVKDALIE-LGLDTKVTILGHVQRGGTAVAHDRWLATLQGVDAVKAVLEFTPETPSPLIGILENKIIRMPLVESVKLTKSVATAIENKDFDKAISLRDTEFIELYENFLSTTVKDDGSELLPVSDR----LNIGIVHVGAPSAALNAATRAATLYCLSHGHKPYAIMNGFSGLIQTGEVKELSWIDVENWHNLGGSEIGTNR-SVASEDLGTIAYYFQKNKLDGLIILGGFEGFRSLKQLRDGRTQHPIFNIPMCLIPATVSNNVPGT---------------------------------------------------EYSLGVDTCLNALVNYTDDIKQSASATRRRVFVCEVQGGHSGYIASFTGLITGAVSVYTPEKKIDLASIREDITLLKENFRHDKGENRNGKLLVRNEQASSVYSTQLLADIISEASKGKFGVRTAIPGHVQQGGVPSSKDRVTASRFAVKCIKFIEQWNKKNEASPNTDAKVLRFKFDTHGEKVPTVEHEDDSAAVICVNGSHVSFKPIANLWENETNVELRKGFEVHWAEYNKIGDILSGRLKLRAEVAALAAENK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P16862-1", "uniprot_id": "PFKA2_YEAST", "id": "P16862-1", "name": "ATP-dependent 6-phosphofructokinase subunit beta", "aln": "MTVTTPFVNGTSYCTVTAYSVQSYKAAIDFYT--KFLSLE--NRSSPDENSTLLSNDS-ISLKILLRPDEKINKNVEA--HLKELNSITKTQDWRSHATQSLVFN-----------TSDILAVKDTLNAMNAPLQGYPTELFPMQLYTLDPLGNVVGVTSTKNAVSTKPTPPPAP-EASAESGLSSKVHSYTDLAYRMKTTDTYPSLPKPLNRPQKAIAVMTSGGDAPGMNSNVRAIVRSAIFKGCRAFVVMEGYEGLVRGGPEYIKEFHWEDVRGWSAEGGTNIGTARCMEFKKREGRLLGAQHLIEAGVDALIVCGGDGSLTGADLFRSEWPSLIEELLKTNRISNEQYERMKHLNICGTVGSIDNDMSTTDATIGAYSALDRICKAIDYVEATANSHSRAFVVEVMGRNCGWLALLAGIATSADYIFIPEKPATSSEWQDQMCDIVSKHRSRGKRTTIVVVAEGAIAADLTPISPSDVHKVLVDRLGLDTRITTLGHVQRGGTAVAYDRILATLQGLEAVNAVLESTPDTPSPLIAVNENKIVRKPLMESVKLTKAVAEAIQAKDFKRAMSLRDTEFIEHLNNFMAINSADHNEPKLPKDKR----LKIAIVNVGAPAGGINSAVYSMATYCMSQGHRPYAIYNGWSGLARHESVRSLNWKDMLGWQSRGGSEIGTNRVTPEEADLGMIAYYFQKYEFDGLIIVGGFEAFESLHQLERARESYPAFRIPMVLIPATLSNNVPGT---------------------------------------------------EYSLGSDTALNALMEYCDVVKQSASSTRGRAFVVDCQGGNSGYLATYASLAVGAQVSYVPEEGISLEQLSEDIEYLAQSFEKAEGRGRFGKLILKSTNASKALSATKLAEVITAEADGRFDAKPAYPGHVQQGGLPSPIDRTRATRMAIKAVGFIK-----DNQAAIAEARAAEENFNADDKTIS------DTAAVVGVKGSHVVYNSIRQLYDYETEVSMRMPKVIHWQATRLIADHLVGRKRVD-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*:*****: ***: *** .* .*. * .: : ***:*:: ** . : * * *** **:**. * ::** .* :* *: * * *********: ** ** *: * : * : *******:. ** ***: :**.** : :* : :** **.*:*::*****:**:***: .:: **::::** . * : : *: * . ::::***: . *:: . ::. : * *:: * ********.. *.** *. * :*. *::* : : . :: : * :* **:*.*: *: * *: : * **. * : : :.::::***. .:*:*. : . : *. : :* .*: :. * : .* . **: :**:* . * : :..*:::****.: . :: * . : : : ::*:*:***:**: : *:* ** :* * ::*** .*: *.*: : ** .**:*. .: ** * *. : : .: :: : ..: .. *:::. .. :: : : : . * * : **:**** *:. ** .:::. :. :: . . *: :: : :..: :* *:. * * . : * ", "identical_positions": 198, "similar_positions": 213, "identity": "18.52%" }, { "cls_id": "homologset.agr.FB:FBgn0003074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6V0-1", "uniprot_id": "G6PI_RAT", "id": "Q6P6V0-1", "name": "Glucose-6-phosphate isomerase", "aln": "--------MAALTRNPEFQKLLEWHRANSANLKLRELFEADPERFNHFSLNLNT-NHGHILLDYSKNLVNKEVLHMLVDLAKSRGVEAARDNMFSGLKINSTEDRAVLHVALRNRSNRSIMMDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKAITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLANLNPESSLFIIASKTFTTQETITNAETAKEWFLQAA-KDPSAVAKHFVALSTNTDKVKEFGIDPKNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFMKTPLDKNAPVLLALLGIWYINFYGCETHAMLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRNGLHHKILLANFLAQTEALMKGKSPEEARKELQAAGKSPEELEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSAVTSHDSSTNGLIGFIKLQRDTKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06745-1", "uniprot_id": "G6PI_MOUSE", "id": "P06745-1", "name": "Glucose-6-phosphate isomerase", "aln": "--------MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNT-NHGHILVDYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAA-KDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRDTKLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06744-1", "uniprot_id": "G6PI_HUMAN", "id": "P06744-1", "name": "Glucose-6-phosphate isomerase", "aln": "--------MAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNT-NHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAA-KDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PDD1-1", "uniprot_id": "A0A8M1PDD1_DANRE", "id": "A0A8M1PDD1-1", "name": "Glucose-6-phosphate isomerase", "aln": "---------MGLNNDPNFIKLEQWYKSSAGNLNMRQMFEADADRFNKFSLQLST-DDGDLLLDFSKNLINEDVMSLLFDMARSVGVEAAREQMFAGEKINFTEGRAVLHTALRNRSNTPIIVDGKDVMPEVNRVLEQMKSFCHKVRSGAWKGFSGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGGPNVWFVSNIDGTHMAKTLAQLNAETTLFIIASKTFTTQETITNAETAREWFLQAA-KDKSAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNFEQLLSGAHWMDNHFRSAPLEQNAPVILALLGVWYVNFFQAETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGTRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRLIPADFLIPAQSQHPIRDNLHHKILMANFLAQTEALMRGKTSDEAKKELQASGLSGDSLEKLLPHKVFQGNKPSNSIIFKKLTPFMLGALVAMYEHKIFVQGVMWNINSYDQWGVELGKQLAKKIEPELQDDAEVHSHDSSTNGLIGFFKKNRF----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52029-1", "uniprot_id": "G6PI_DROME", "id": "P52029-1", "name": "Glucose-6-phosphate isomerase", "aln": "----MAGPLPPLNQEAAFQKLQEYYDSKGKDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDLLLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGKG-LHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHS-KEPESVAKHFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGNELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCNEVSTHDSSTNGLINFIKANWK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12709-1", "uniprot_id": "G6PI_YEAST", "id": "P12709-1", "name": "Glucose-6-phosphate isomerase", "aln": "MSNNSFTNFKLATELPAWSKLQKIYESQGKTLSVKQEFQKDAKRFEKLNKTFTNYDGSKILFDYSKNLVNDEIIAALIELAKEANVTGLRDAMFKGEHINSTEDRAVYHVALRNRANKPMYVDGVNVAPEVDSVLKHMKEFSEQVRSGEWKGYTGKKITDVVNIGIGGSDLGPVMVTEALK-HYAGVLDVHFVSNIDGTHIAETLKVVDPETTLFLIASKTFTTAETITNANTAKNWFLSKTGNDPSHIAKHFAALSTNETEVAKFGIDTKNMFGFESWVGGRYSVWSAIGLSVALYIGYDNFEAFLKGAEAVDNHFTQTPLEDNIPLLGGLLSVWYNNFFGAQTHLVAPFDQYLHRFPAYLQQLSMESNGKSVTRGNVFTDYSTGSILFGEPATNAQHSFFQLVHQGTKLIPSDFILAAQSHNPIENKLHQKMLASNFFAQAEALMVGKDEEQVKAEGATGG--------LVPHKVFSGNRPTTSILAQKITPATLGALIAYYEHVTFTEGAIWNINSFDQWGVELGKVLAKVIGKELDNSSTISTHDASTNGLINQFKEWM-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : ** : : *.:: * : .**.: . : . : ..:*.*:*** :..:: *. :*: * . *: ** * :** **.*** *.*****.. .: :*. :* *:* * :**.* . * ** *:* :** ***::***********:******* : * :********:*:.* :. *::**::******* ****** :*: *:*. : :: . :****.***** :* :****. *** * .*******:*******:.* :*:::** :*.**. :*:** :*::.* *:: .**.:** * : .:** : *:***:***.**:** .****** :::.. ..: **.*::***.**.**:*:**:****::**.**: ..*:::** *:*:* :**:**:**** ** ::.: * .* *:***** **:*:.**: *::* ****:* *** *.:* :*:***:********* *** * **: : :**:******. :* ", "identical_positions": 256, "similar_positions": 160, "identity": "45.07%" }, { "cls_id": "homologset.agr.FB:FBgn0003076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0F9-1", "uniprot_id": "PGM1_MOUSE", "id": "Q9D0F9-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYPDQKP-GTSGLRKRVKVFQSNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGG-IILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQ-------SVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGT-GSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38652-1", "uniprot_id": "PGM1_RAT", "id": "P38652-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYPDQKP-GTSGLRKRVKVFQGNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGG-IILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIASYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQ-------RVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGT-GSAGATIRLYIDSYEKDAAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36871-1", "uniprot_id": "PGM1_HUMAN", "id": "P36871-1", "name": "Phosphoglucomutase-1", "aln": "----MVKIVTVKTQAYQDQKP-GTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIR--KIKAIGG-IILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDL-KVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNR---LKIRIDAMHGVVGPYVKKILCEELGAPANSAVN-CVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQ-------SVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGT-GSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZF8-1", "uniprot_id": "PGM5_MOUSE", "id": "Q8BZF8-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPTGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTATEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGG-IILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRNIFDFNAIKSLLTGPSQ---LKIRVDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSTALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQ-------SVEEIVRDHWAKYGRHYYCRFDYEGLEPKATYYIMRDLEALVTDKSFIGQQFAVGSHIYSIAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATIRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVR9-1", "uniprot_id": "PGM5_RAT", "id": "D3ZVR9-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPTGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTATEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGG-IILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYTICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFNAIKSLLTGPSQ---LKIRVDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQ-------SVEEIVRDHWAKYGRHYYCRVLYEAKSPKATYYIMRDLEALVTDKSFIGQQFAVGSHIYSIAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATIRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15124-1", "uniprot_id": "PGM5_HUMAN", "id": "Q15124-1", "name": "Phosphoglucomutase-like protein 5", "aln": "MEGSPIPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIR--KIKAAGG-IILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDL-RIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFHAIKGLLTGPSQ---LKIRIDAMHGVMGPYVRKVLCDELGAPANSAIN-CVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQ-------SVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSS-SGVRATLRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0B3-1", "uniprot_id": "PGM5_DANRE", "id": "B0R0B3-1", "name": "Phosphoglucomutase-like protein 5", "aln": "METNPIPILTIQTTPFDDQRP-GTNGLRKKTAVFESNNNYLQNYIQSVLSSIDLRDRQGCTMVVGSDGRYFSRAATEVIVQMAAANGIGRLVIGHNGILSTPAVSCIIR--KIKAIGG-IILTASHSPGGPGGDFGIKFNVANGGPSPDTVIERIHQVSRTLEEYAICPDL-HIDLSRLGRQDFDLENKFKPFRVEIVDSVEIYFNLLRGIFDFSGIKSLLTGPNQ---LKIRIDAMNGVMGPYVRRILCDELGAPANSAVN-CVPLEDFGGQHPNPNPAFAGPLVDSMKGGEFGFGAAFDADGDRYMIMGENGFFVSPSDSLAVMAANLSCIPYFSQRGIRGFARSMPTSTAIDRVAKAMKVALYETPTGWRFFGNLLDSGRCSFCGEESFGTGSDHIRDKDGLWSVLVWLSIMAVRKQ-------GVEEIVRDHWAKLGRNYFCRFDYEGVDGKAAFYLMRDLEAVITDKAFTTQKFSVGNTVYSVEKADNFEYIDPVDGSVSRKQGLRIIFTDSSRIIFRLSGSGSGTGATVRIYAESYERDPERHNRETQVVLGPLIAIALKISNIHERTGRRGPNIIT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUY9-1", "uniprot_id": "PGM_DROME", "id": "Q9VUY9-1", "name": "Phosphoglucomutase 1", "aln": "---MSLTVEIVATKPYEGQKP-GTSGLRKKVKVFT-QPNYTENFVQAILEANG-AALAGSTLVVGGDGRFYCKEAAELIVRLSAANGVSKLLVGQNGILSTPAVSSLIR--HNKALGG-IVLTASHNPGGPENDFGIKFNCENGGPAPDAFTNHIYKITTEIKEYKLVRNL-QIDISKVGVTSFDIAG--KPFTVEVIDSVANYVRHMEEIFDFAKLKDFVSGKATGKPLKMRIDAMNGVTGSYVREIFLNRLGATESSVVH-TTPLPDFGGLHPDPNLTYAKDLVDTVAQGDYDIGAAFDGDGDRNMIIGSKAFFVTPSDSLAVIAHYLEAIPYFQKNGVQGFARSMPTASAVDLVGRKLGKEVFEVPTGWKYFGNLMDAGRLCLCGEESFGTGSNHIREKDGIWAVLAWISVMQHTGK-------GIEDILKQHWSVYGRNYFTRYDYEECASDPCNEMVATMEKTITAPEFVGKSYSSGGKTYKVKEADNFSYTDPVDKSVATKQGLRIVFEDGSRIVVRLSGT-GSSGATVRLYIDSYEKE--NVLGQASVMLKPLIDIALEISQLPKFTGRNAPTVIT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37012-1", "uniprot_id": "PGM2_YEAST", "id": "P37012-1", "name": "Phosphoglucomutase 2", "aln": "---MSFQIETVPTKPYEDQKP-GTSGLRKKTKVFKDEPNYTENFIQSIMEAIP-EGSKGATLVVGGDGRYYNDVILHKIAAIGAANGIKKLVIGQHGLLSTPAASHIMRTYEEKCTGG-IILTASHNPGGPENDMGIKYNLSNGGPAPESVTNAIWEISKKLTSYKIIKDFPELDLGTIGKN-----KKYGPLLVDIIDITKDYVNFLKEIFDFDLIKKFIDNQRSTKNWKLLFDSMNGVTGPYGKAIFVDEFGLPADEVLQNWHPSPDFGGMHPDPNLTYASSLVKRVDREKIEFGAASDGDGDRNMIYGYGPSFVSPGDSVAIIAEYAAEIPYFAKQGIYGLARSFPTSGAIDRVAKAHGLNCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHVREKDGVWAIMAWLNILAIYNKHHPENEASIKTIQNEFWAKYGRTFFTRYDFEKVETEKANKIVDQLRAYVTKSGVVNSAFP-ADESLKVTDCGDFSYTD-LDGSVSDHQGLYVKLSNGARFVLRLSGT-GSSGATIRLYIEKYCDDKSQYQKTAEEYLKPIINSVIKFLNFKQVLGTEEPTVRT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33401-1", "uniprot_id": "PGM1_YEAST", "id": "P33401-1", "name": "Phosphoglucomutase 1", "aln": "---MSLLIDSVPTVAYKDQKP-GTSGLRKKTKVFMDEPHYTENFIQATMQSIP-NGSEGTTLVVGGDGRFYNDVIMNKIAAVGAANGVRKLVIGQGGLLSTPAASHIIRTYEEKCTGGGIILTASHNPGGPENDLGIKYNLPNGGPAPESVTNAIWEASKKLTHYKIIKNFPKLNLNKLGKN-----QKYGPLLVDIIDPAKAYVQFLKEIFDFDLIKSFLAKQRKDKGWKLLFDSLNGITGPYGKAIFVDEFGLPAEEVLQNWHPLPDFGGLHPDPNLTYARTLVDRVDREKIAFGAASDGDGDRNMIYGYGPAFVSPGDSVAIIAEYAPEIPYFAKQGIYGLARSFPTSSAIDRVAAKKGLRCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHIREKDGLWAIIAWLNILAIYHRRNPEKEASIKTIQDEFWNEYGRTFFTRYDYEHIECEQAEKVVALLSEFVSRPNVCGSHFP-ADESLTVIDCGDFSYRD-LDGSISENQGLFVKFSNGTKFVLRLSGT-GSSGATIRLYVEKYTDKKENYGQTADVFLKPVINSIVKFLRFKEILGTDEPTVRT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * .: .*:* * .***: . :* . :* *::*: :.: *:***.***:: . :. :.****: :*::*: *:*****.* ::* . *. ** *:***** **** .::*:*:* ****:*: . : * : : : * : :: .:::. :* *: *:::* . * :. **** :* :: *: .*:::*: *.* : :: :.:* . ...:: * **** **:** ::* *:. : . :*** *.**** ** * **.*.**:*::* **** : *: *:.**:**: *:* *. :*.*:**::* *:*: : :**********:*:*:***:*:::.*:.:: : :: * :.* ** :: * :* . :: : : . . :. . .: . ..*.* * :* ::: :*** : : :.::::.***.: .. **:*:* :.* . .. * *:* ::. .: : * *.: *", "identical_positions": 164, "similar_positions": 191, "identity": "28.13%" }, { "cls_id": "homologset.agr.FB:FBgn0003079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LDY4-1", "uniprot_id": "A0ABK0LDY4_RAT", "id": "A0ABK0LDY4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAALSGGGGSSSGGGGGGGGGGGGG-GGGGAEQGQALFNGDMEPEAGAGA--AASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGADFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQTPTDVSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQD---GEKKPIGWDTDISWLTGEELHVEVLENVPLTTHN---FVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNY--DQLDLLFVSKFFEHHPVPQEEAFSAETTLPSGCS-SAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHIN-TIEPVNIDEKFPEVELQDQRDLIRDQGFRGDGAPLNQLMRCLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTTGLSATPPASLPGSLTN-VKALQKSPGPQRERKSSSSSSSTEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28028-3", "uniprot_id": "BRAF_MOUSE", "id": "P28028-3", "name": "Serine/threonine-protein kinase B-raf", "aln": "MAALSGGGGSSSGGGGGGGGGGGGGDGGGGAEQGQALFNGDMEPEAGAGA--AASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESL---------------------------------VFQTPTDASRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQD---GEKKPIGWDTDISWLTGEELHVEVLENVPLTTHN---FVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNY--DQLDLLFVSKFFEHHPVPQEEASFPETALPSGSS-SAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHIN-TIEPVNIDD------------LIRDQGFRGDG----------------------------------------GSTTGLSATPPASLPGSLTN-VKALQKSPGPQRERKSSSSSSS-EDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15056-1", "uniprot_id": "BRAF_HUMAN", "id": "P15056-1", "name": "Serine/threonine-protein kinase B-raf", "aln": "MAALSGG-------------------GGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQD---GEKKPIGWDTDISWLTGEELHVEVLENVPLTTHN---FVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNY--DQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHIN-TIEPVNIDD------------LIRDQGFRGDG----------------------------------------GSTTGLSATPPASLPGSLTN-VKALQKSPGPQRERKSS---SSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11345-1", "uniprot_id": "RAF1_RAT", "id": "P11345-1", "name": "RAF proto-oncogene serine/threonine-protein kinase", "aln": "-----------------------------------------MEHIQGAWK----------TIS-NGFGLKDAVFDGSSCISPTIVQQFGYQRR------------------------------------------------------------------ASDDGKLTDSSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHN---FARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW--SNIRQLLLFPNSTASDS----------GVPAPPSFTMRRMRESVSRMPASSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMI-----------EDAIRSHSESASP----------------------------------------------SALSSSPNNLSPTGWSQPKTPVPAQRERAPG--SGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRA-AHTEDINACTLTTSPRLPVF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N57-1", "uniprot_id": "RAF1_MOUSE", "id": "Q99N57-1", "name": "RAF proto-oncogene serine/threonine-protein kinase", "aln": "-----------------------------------------MEHIQGAWK----------TIS-NGFGLKDAVFDGSSCISPTIVQQFGYQRR------------------------------------------------------------------ASDDGKLTDSSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHN---FARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW--SNIRQLLLFPNSTVGDS----------GVPAPPSFPMRRMRESVSRMPASSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLHVDSRMI-----------EDAIRSHSESASP----------------------------------------------SALSSSPNNLSPTGWSQPKTPVPAQRERAPG--SGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRA-AHTEDINACTLTTSPRLPVF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04049-1", "uniprot_id": "RAF1_HUMAN", "id": "P04049-1", "name": "RAF proto-oncogene serine/threonine-protein kinase", "aln": "-----------------------------------------MEHIQGAWK----------TIS-NGFGFKDAVFDGSSCISPTIVQQFGYQRR------------------------------------------------------------------ASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHN---FARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW--SNIRQLLLFPNSTIGDS----------GVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMI-----------EDAIRSHSESASP----------------------------------------------SALSSSPNNLSPTGWSQPKTPVPAQRERAPV--SGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRA-AHTEDINACTLTTSPRLPVF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NV26-1", "uniprot_id": "A0A8M1NV26_DANRE", "id": "A0A8M1NV26-1", "name": "RAF proto-oncogene serine/threonine-protein kinase", "aln": "-----------------------------------------MEHFQGAWK----------SVSSHGFGCKDSVFEDS-CMSPSILKTFPYRR-------------------------------------------------------------------LSDDGRIPD-SKTSSTIRVFLPNKQRTVVNVRAGMTLRNCLIKALKVRGLQPECCAVFKLQREHSAKKLRMDWSTDSTSLVGEELLVEVLDHVPLTTHN---FVRKTFLKLAFCDICQKFLLHGFRCQTCGYKFHEHCSTKVPTMCVDW--SNIRQLLLFP--TPGEN----------GALTLPPLSSRRMQN--SRFSFSPYHRYSTPNALNYITPLPSPGVSLGHKVLSTSTPNVHMVSTTQPVDEAAY-----------QEALR-HDESGS-----------------------------------------------------PQNLSPTEWS--KTPAPAHREKAPS--SNTQEK-RIRPREKRDSSYYWEIEATEVLLLSRIGSGSFGTVYKGKWHGDVAVKILKVINPTPEQLQAFRNEVAVLRKTRHVNIVLFMGYMTKVKLAIVTQWCEGSSLYKHLHVQETNFQMFQLMDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKARWSGSHRVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGIVLYELMTGELPYSMIGNRDQIIFMVGRGYLSPDLSKLYKSCPKAMKRLVSDCIQKTKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRA-THTEDMNVCTLALTSAFK------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14056-1", "uniprot_id": "ARAF_RAT", "id": "P14056-1", "name": "Serine/threonine-protein kinase A-Raf", "aln": "-----------------------------------------MEPPRGPP--------------------------------------------------------------------------------------------------------------ASG----AEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIK---GRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHN---FVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDM--STNRRQFYHSIQDLSG-----------GSRQQEVPSNLSVNELLTPQGPSPFTQQRDQEHFSFPA---PAN-PPLQRIRSTSTPNVHMVSTTAPMDSSLM-----------QFTAQSFSTDAAG---------------------------------------RGG-DGAPRGSPSPASVSS-GRKSPHSKLPAEQRERK---SLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHR--TQADELPACLLSAARLVP------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04627-1", "uniprot_id": "ARAF_MOUSE", "id": "P04627-1", "name": "Serine/threonine-protein kinase A-Raf", "aln": "-----------------------------------------MEPPRGPP--------------------------------------------------------------------------------------------------------------VSG----AEPSRAVGTVKVYLPNKQRTVVTVREGMSVYDSLDKALKVRGLNQDCCVVYRLIK---GRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHN---FVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDM--STNRRQFYHSIQDLSG-----------GSRQQEAPSNLSVNELLTPQGPSPFTQQRDQEHFSFPA---PAN-PPLQRIRSTSTPNVHMVSTTAPMDSSLM-----------QFTAQSFSTDAAG---------------------------------------RGG-DGAPRGSPSPASVSS-GRKSPHSKLPSEQRERK---SLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHR--TQADELPACLLSAARLVP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10398-1", "uniprot_id": "ARAF_HUMAN", "id": "P10398-1", "name": "Serine/threonine-protein kinase A-Raf", "aln": "-----------------------------------------MEPPRGPP--------------------------------------------------------------------------------------------------------------ANG----AEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIK---GRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHN---FVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDM--STNRQQFYHSVQDLSG-----------GSRQHEAPSNRPLNELLTPQGPSPRTQHCDPEHFPFPA---PAN-APLQRIRSTSTPNVHMVSTTAPMDSNLI-----------QLTGQSFSTDAAGS--------------------------------------RGGSDGTPRGSPSPASVSS-GRKSPHSKSPAEQRERK---SLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHR--TQADELPACLLSAARLVP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5FBD1-1", "uniprot_id": "Q5FBD1_DANRE", "id": "Q5FBD1-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------MSNTSSCS--------------------------------------------------------------------------------------------------------------SSGETSPDDTPRGGGTIRVYLPNKQRTVVNVRPGQTVYDSLDKALKVRGLSQDCCAVFRLLE---GRKRLTEWDTDITPLVGEELLVEVLDDVPLTMHN---FVRKTFFKLAYCDFCHKFLFNGFRCQTCGYKFHQHCSSKVPTVCVDM--DTMTKRCVNNTEDCPA-----------ILIYPATNSISQSDLPLTSDSPGGELPSSPSNFCLFIR---GEDGQSLQRHRSTSTPNVHMVSTLEPGAAGLL-----------EEP---FKISTVAS--------------------------------------STGYESSPKPSTSPPHLGSPGRKPPKS--PSEPKERKQ--SSSDDKKKVHRGGYRDSSYYWEVHPREVSMLKRIGAGSFGTVFKGKWHGDVAIKILKVTEPTPEQLQAFKNEMQVLRKTRHVNILLFMGFMTRPNFAIITQWCEGSSLYRHLHVTETKFDTMRRIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGWTVKIGDFGLATVKSRWSGSQQVEQPSGSILWMAPEVIRMQDTNPYTFQSDVYGYGVVLYELMSGTLPYSNINNRDQIIFMVGRGYLSPDLSKLYSNCPKSMKRLIIDCLKFKRDERPLFPQILVSIEQVQELLPKIERSASEPSLHRA-VHAEDLNPLLLHTTRFL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11346-1", "uniprot_id": "KRAF1_DROME", "id": "P11346-1", "name": "Raf homolog serine/threonine-protein kinase Raf", "aln": "MSSESSTEGDSDLYDPLAEELHNVQLVKHVTRENIDALNAKFANLQEPPAMYLIEYQELTSKLHELEAKEQELMERLNSQDQQEDSSLVERFKEQPHYQNQTQILQQQRQLARVHHG---------------------------------NDLTDSLGSQPGSQCGTLTRQPKILLRAHLPNQQRTSVEVISGVRLCDALMKALKLRQLTPDMCEVSTTHS----GRHIIPWHTDIGTLHVEEIFVRLLDKFPIRTHIKHQIIRKTFFSLVFCEGCRRLLFTGFYCSQCNFRFHQRCANRVPMLCQPFPMDSYYQLLLAENPDNGVG---------FPGRGTAVRFNMSSRSRSRRCSSSGSSSSSKPPSSSSGNHRQGRPPRISQDDRSNSAPNVCIN-NIRSVTSEVQ---------------RSLIMQARP--------------------------------------------------PLPHPCTDHSNSTQASPTSTLKHNRPRARSADESNKNLLLRDAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHWHGPVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMGCVSKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQNDEFLYLPSPKTPVNFNNFQFFGSAGNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::..***:*** * . * : :.* *** :* * : * * : * * * **: * .*:..*: * : ****:.*.:*: * ::*: ** *. *.::**::*:..** :* . . : *.*:*** : . . * : . .. * :.. .: :.* *:: :: : ***:******::.:*** **:* *:* *:. * ***:**: :*:**** **:**** :: :**:**********:*:*: :*.*. :*:.**.**********.*****:*********. :**********.*:**** : :* :**:****.******: **::******.:*:*:***:: ***. *. :***:****** **:*:: ...*::::** :*:: .:**** :* :* : . ****.******.* : : ::: . ", "identical_positions": 208, "similar_positions": 142, "identity": "24.44%" }, { "cls_id": "homologset.agr.FB:FBgn0003089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3AWA0-1", "uniprot_id": "A0A8M3AWA0_DANRE", "id": "A0A8M3AWA0-1", "name": "Uronyl 2-sulfotransferase", "aln": "-----MKNYSSSSRLNNHSASHGTDRNSRR--------------GFWLSALGLRFSLRDYAFCMATLLLFCLGSLFYQLNGGPPKVLLEIRQYLGESTFVDDHGPPT------------------------------------------------PRELPFP----------------------------------------------------SQVIYNRVGKCGSRTVVLLLRILAEKHQFNLVSSDIHNKTRLTKHEQVSGWVDLITNISNIPQPFLYTRHVHFLNFTRFRIEQPVYINIIRDPINRFLSNYFFRRFGDWRGEQNHLIRT---PQMKDDERYLDINVCIMENYPECSNPRLFYIVP---------YFCGQHPQCREPG--MWAVERAKQNVIENFLLVGILEELEDVLLLLERLLPHYFSDVLTIYKSPAFWKMGNLTGTVKKHMPTIEALQVLYQRMKYEYDFYNFIRDQFHLTKKKIGLKSSSQNSAHEPDFLRELALRTHEPLEEEEEEEEEEDDIGQEDANIWLVQP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BJ3-1", "uniprot_id": "UST_DROME", "id": "Q86BJ3-1", "name": "Uronyl 2-sulfotransferase homolog pip", "aln": "MSLNAERSYKMKLRDVENAFKYRRIPYPKRSVELIALLAISCTFFLFMHTNKLNSRLKEMEVKLQPSEFSALGLTGNHISGHDAGKHDDINTLHGTYQYLKSTGQKVGYNVHDRRSSEEQLRTPTAHGHHHDHHSHHHHMHQQEKIDGHKHKASHDKQLAVPDNKHKEDEVHYEDDEDEVEENDDDLANDVGTTDSEGFNFKADLLNNTKYAEVDFVFFNRVPKVGSQSLMELMARLGKINGFTHARNKGSAHETIVMNKQRQ--NDLIADLLTRPKPHIYSQHIAYINFTRFHLPKPIYINLIRDPIDRIISWHYYIRAPWYYRDMQAKLGENAIPMPSEEFMNLDLDTCVRNHDPHCTFTQMQIKNPVGDHRRQTLFFCGMNQKLCMPFNSEAAMQKAKRTVETEYAVVGTWEDTNITLSVLEAYIPRYFRNAKVAYY-LGKDRLSRVNRNNVTRIVSDETRLILRKNLTNEIEFYEFCKQRLYLQYAALSHG----KRFGEDDYL----------LVPEQQNEYNEDY-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*. . * ::: .: .:* ::: : *. *:: . : . : .** ::.* . :*. * ::.. * . ::*..* . *::*** * **:::: *: *.: : *. . .. : :. ::* . ***::: . *:*.:*::*: ::*****:: :*:***:*****:*::* ::: * : : : : * .:: **::.*: :: *.*: .:: * :*** : : * *:::**:.* :: :** *: : .* :** :*:** :. . * . ::..:. . .:: : *: :* :.:. * :**:* :::::* :. : * *:* * *:::* :** ", "identical_positions": 88, "similar_positions": 153, "identity": "16.18%" }, { "cls_id": "homologset.agr.FB:FBgn0003090", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6IBC5-1", "uniprot_id": "PRIC2_RAT", "id": "A6IBC5-1", "name": "Prickle-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTVMPLE------MEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQIKGGDIAVFASRAG-HGICWHPPCFICTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMRHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATENCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEET--MLNQHSQLQVSSNRLSADVDP-LSVQMDLLSLSS--------------------QTPSLNRD-PIWRSRDEPFHYGNKMEQNQSQSPL-QLLSQCNIRTSYSPGGQAAGAQP------DMWAKHF---SNPKRSSSMALKGHGG--SFIQECRE-DYYPGRLMSQESYSDMSSQS--FSETRGSIPVPKYEEEEEEEEEEGGISTQQCRPRRPLSSLKYTEDMTPTEQTPRGSMESLALSNATG-LSAEGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFRSAESVRSLLSAQQYQEMEGNLHQLSNPLGYRDLQSHGRMHQSFDFDGGIASSKLPGQEG--VHIQPMSERTRRRTTSRDD-NRRFR--PHRS--------RRSRRSRSDNALHLASEREVIARLKDRPPLRAREDYDQFVRQRSFQESMGQG--SRRDLYSQCPRTVSDLALQN----AFGERWGPY-FTEYD----WCSTCSSSSES-DNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGVPKSSTLGGRGQLHSRKR-QKSKNCIIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Y24-1", "uniprot_id": "PRIC2_MOUSE", "id": "Q80Y24-1", "name": "Prickle-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTVMPLE------MEKTISKLMFDFQRSSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYVNSAGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQIKGGDIAVFASRAG-HGICWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMRHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEA--MLNQHSQLQVSSNRLSADVDP-LSVQMDLLSLSS--------------------QTPSLNRD-PIWRSREEPFHYGNKMEQNQSQSPL-QLLSQCNIRTSYSPGGQGAGAQP------DMWAKHF---SNPKRSSSMALKGHGG--SFIQECRE-DYYPGRLMSQESYSDMSSQS--FNETRGSIPVPKYEEEEEEEE--GGISTQQCRPRRPLSSLKYTEDMTPTEQTPRGSMESLALSNATG-LSAEGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFRSAESVRSLLSAQQYQEMEGNLHQLSNPLGYRDLQSHGRMHQSFDFDGGIASSKLPGQEG--VHIQPMSERTRRRTTSRDD-NRRFR--PHRS--------RRSRRSRSDNALHLASEREVIARLKERPPLRAREDYDQFMRQRSFQESLGQG--SRRDLYSQCPRTVSDLALQN----AFGERWGPY-FTEYD----WCSTCSSSSES-DNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGVPKSSTLGGRGQLHSRKR-QKSKNCIIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3G6-1", "uniprot_id": "PRIC2_HUMAN", "id": "Q7Z3G6-1", "name": "Prickle-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTVMPLE------MEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAG-HGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEP--MLNQHSQLQVSSNRLSADVDP-LSLQMDMLSLSS--------------------QTPSLNRD-PIWRSREEPYHYGNKMEQNQTQSPL-QLLSQCNIRTSYSPGGQGAGAQP------EMWGKHF---SNPKRSSSLAMTGHAG--SFIKECRE-DYYPGRLRSQESYSDMSSQS--FSETRGSIQVPKYEEEEEEEG---GLSTQQCRTRHPISSLKYTEDMTPTEQTPRGSMESLALSNATG-LSADGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQEG--VRIQPMSERTRRRATSRDD-NRRFR--PHRS--------RRSRRSRSDNALHLASEREAISRLKDRPPLRAREDYDQFMRQRSFQESMGHG--SRRDLYGQCPRTVSDLALQN----AFGDRWGPY-FAEYD----WCSTCSSSSES-DNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGLPKSSTLGGRGQLHSRKR-QKSKNCIIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1REQ6-1", "uniprot_id": "F1REQ6_DANRE", "id": "F1REQ6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLE------MEKTVTKLMYDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSSLPEDKVPYVNSPGEKYRIKQLLHQLPPHDNEVRYCNSLDDEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAG-HGVCWHPQCFVCSMCDELLVDLIYFYQDGKIFCGRHHAERLKPRCSACDEIILADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCTCFESLYAEYCDSCGEHIGIDQGQMTYDGQHWHATEACFSCARCKKSLLGRPFLPKQGQIFCSRACSVGDDQNGSDSSDSAFQSARSREARRSSSKS-NKSSTGGS--GGDGHQSGKASAMRFSADVDP-LSLQMDLLSLSS--------------------QTPSLNRESPSWKTQAEMFGYEGRNE--LSTNPL-HLLSQCNIRTSYSSN-LSPGHLS------DPRPKEP---ASSKRPPVSALKGKSLNENWFQQGPE-DYYPPALRTQASFNEVPHNS--FMDKR-SVSLHVFQREKEKDVG-----PQMSRSRNPISALGFSEQLTPLEQTPRGSMESLALSNATG-TSADGGSKRQEHLSRFSMPDLSKDSGMNVSEK-SNMGTLNSSVQFHSSESLRSLNSAQPYLELEAPVQVRFPVQYPREPSGINALPPGFAYQEEDRVSLVSNANN--ARLPPMSERTRRRSIDHEEPRRRHH--HHRS--------RRSRRSRSDNALNLVAERRPAP---KRSQLHAREDYDQFPLPRGSRDTYGSGR-LRQQPFRPCPRTTSDLTLQNP---ALHRHQGPYSWDQYDYNDDWCSTCSSSSES-EDEGYFLGEPIPRPIQLRHMTSEELLRKYNSSGLGASGQFGSRGQLHMRKR-RKSKNCIIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TUF1-1", "uniprot_id": "A0AB32TUF1_DANRE", "id": "A0AB32TUF1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALD------MERTVSKIMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYRFFPEDKVPYVNSIGEKHRIKQLLQQLPPHDNEVRYCTSLDEEEKRELKIFSNQRKRDNLGRGTVRPLPLTITGAICQQCGEQIKGGDIAVFASRVA-HGLCWHPHCFVCGVCSELLVDLIYFQLEGKIYCGRHHAERLKPRCSACDEIIFADECTEAEGQHWHMKHFCCYECEAPLGGQRYIMREGHPHCCNCFENLYAEYCDSCGEHIGIDQGQMTYEGQHWHATEDCFSCARCSQSLLGRPFLPKQGLIYCSRLCSQGDEAELSDSSDSAFQSARSRQSHHSASVGKDGSKGKGE--TVRQTSSGPTT---LSGDAEP-LAVQMDLLSVASPAPSRTPHRTPTRTPSRTSSRSPSLNREQTVWVNRDEPYSYESQRDSSTSPNPH-QLRSQCSIRTAYPPSPNQPPKIVSSQ---EAWSKEPPGGNSKKPPVMAALRGHSFNENWMHHGQEPEFHPPKLKTQMSFNEVSSRNSGFLDKR-SISVQGFPREMR---------PPLLRSRHQFRPN--FGELTPLEQTPRGSADSLALSYTTAGNSLDGTSRRQEHFSRFSMPDLSKDSGVNVSEK-GTVGTLNSSVQFRSTESLSSVP--RPLADIGMPVRLRYPPPLYWDSPRGLSFEDPVKGRIGLAGSMSCMQDGNAQAMTPRPRRAQAQNSPRQQ-RQRQR--HHRKNHKSQKYQYRSRRSRSDNALHLATEDQSFP---GDPIHRFHNDFERPSSSRLSHNLFGANYGYRQQFFRPCPRTTSDLTLQDPGGPQIGQYMGRYGEAVED-EDQFCSTCSSSSEASDDDAYLPGEGIPRPVQLRYFDNEELRHRYSP------TLVGGHTQLHTRKR-RKSKNCIIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q71QF9-1", "uniprot_id": "PRIC1_RAT", "id": "Q71QF9-1", "name": "Prickle-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLE------MEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAMMHAVCEQCGLQMNGGEVAVFASRAG-PGVCWRPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDIHASDSSDSAFQSARSRDSRRSVRMGRSSRSADQCRQSLLLSPALNYKFPGLSGSADDTLSRKLDDVSLSG--------------------QGAGFAHE-EFWKARVDQEASEDPEEWAEHEDYMTQLLLKFGDKNLFQQPPSEVDMRASEHWIPDNMVTNKP--EAKQNHQSLASKKYQSDMYWAQ-------------SQDGLGDSAYGS--HPGPASSRRLQELDLDHGAAG-----YNHDQTQWYEDSLECLSDLKPEQ--SVRDSMDSLALSNITG-ASVDGESK--PRPSLYSLQNFE-EIEAEDCEKMSNMGTLNSSMLHRSAESLKSLNSELCPEKIIP----EEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGSYD-IEIRQPPMSERTRRRVYHFEERGS-RP-HHHRH--------RRSRKSRSDNALNLVTERKYSA--KDRLRLYTPDNYEKFIQSKGARELQAYM--QNANLYGQYAHTTSDYALQNP---GMTRFLGLYGDDDDS----WCS-SSTSSSDSEEEGYFLGQPIPQPRPQRFTYYT--DDLSSPASALPTPQFNQRTTKSKKKKGHRGKNCIIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U5C7-1", "uniprot_id": "PRIC1_MOUSE", "id": "Q3U5C7-1", "name": "Prickle-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLE------MEPKMSKLVFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLQMNGGEVAVFASRAG-PGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDIHASDSSDSAFQSARSRDSRRSVRMGRSSRSADQCRQSLLLSPALNYKFPGLSGNADDTLSRKLDDVSLASR-------------------QGAGFANE-EFWKARVEQEASEDPEEWAEHEDYMTQLLLKFGDKNLFQQQSSEVDPRASEHWIPDNMVTNKP--EVKPNHQGLASKKYQSDMYWAQ-------------SQDGLGDSAYGS--HPGPASSRRLQELDLDHGAAG-----YTHDQSQWYEDSLECLSDLKPEQ--SIRDSMDSLALSNITG-ASVDGESK--PRPSLYSLQNFE-EIEAEDCEKMSNMGTLNSSMLHRSAESLQSLNSGLCPEKILP----EEKPAHLPVLRRSKSQSRPQQVKFSDDVIDNGSYD-IEIRQPPMSERTRRRAYHFEERGS-RP-HHHRH--------RRSRKSRSDNALNLVTERKYSA--KDRLRLYTPDNYEKFIQNKSARELQAYM--QNANLYSQYAHATSDYALQNP---GMNRFLGLCGEDDDS----WCS-SSTSSSDSEEEGYFLGQPIPQPRPQRFTYYT--DDLSSPASALPTPQFTQRTTKSKKKKGHKGKNCIIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MT3-1", "uniprot_id": "PRIC1_HUMAN", "id": "Q96MT3-1", "name": "Prickle-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLE------MEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVAVFASRAG-PGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKFPGLSGNADDTLSRKLDDLSLSR--------------------QGTSFASE-EFWKGRVEQETPEDPEEWADHEDYMTQLLLKFGDKSLFQPQPNEMDIRASEHWISDNMVKSKT--ELKQNNQSLASKKYQSDMYWAQ-------------SQDGLGDSAYGS--HPGPASSRRLQELELDHGASG-----YNHDETQWYEDSLECLSDLKPEQ--SVRDSMDSLALSNITG-ASVDGENK--PRPSLYSLQNFE-EMETEDCEKMSNMGTLNSSMLHRSAESLKSLSSELCPEKILP----EEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYD-IEIRQPPMSERTRRRVYNFEERGS-RS-HHHRR--------RRSRKSRSDNALNLVTERKYSP--KDRLRLYTPDNYEKFIQNKSAREIQAYI--QNADLYGQYAHATSDYGLQNP---GMNRFLGLYGEDDDS----WCS-SSSSSSDSEEEGYFLGQPIPQPRPQRFAYYT--DDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q6J9-1", "uniprot_id": "F1Q6J9_DANRE", "id": "F1Q6J9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELENRGGLHMGSKVNKLTLGFQRSSTSDDDSGCALEEYAWVPPGLRPEQVALYFSCLPEDKVPYVNSPGEKQRIKQLLYQLPPHDNEVRYCQSLSEEEKKELHMFSIQRKKEALGRGTLKILPRTVHHAACEHCGERLGGGEMAVCVSRAAAAGQCWHPACFTCSTCSELLVDLIYFYHDGKVHCGRHHAELLKPRCSSCDEIIFADECTEAEGRHWHMKHFSCSECEVILGGQRYIMKDGRPFCCGCFQSLYAEYCQACAQHIGVDHAQMTYDGLHWHATDACFSCAQCKSSLLGCPFLPRQGRIYCSKACSLGEDVQASDSSDSAFQSARSRESRRSVKMGKSSRSADQCRQSLLFSPASNYKFPGLSGNADDTLSKRLSQL---------------------------NFADN-HFWRNREDQEAPEDHEEWAEHDDYMTQLLLKFGEHGMFQDTRTDLSIWT------DSELKNKT--GSGGNS-SLASKKYKADMYWTQ-------------SQDGLGDSAYGS--HPGPASSRKLQDLDLEHGASF-----KHEDNKQWFNDSLECITDQLKEADLNIRDSMDSLALSNITG-ASVDGDIK--DKPLLFSLQKFS-DLDR--CENTSNMGTLNSSMKSLTSDLDRTQVIEEQQEQGVPSPEVHPKPPRLPVLRRSKSQSKTQQVKFSDDVIDNGRYDELKVRQPPMSERTRRRAFQFDEQDHQRPRHHHRR--------RRSRMSRSDNALHLAPK-------EEKPRVCFKD----------DRRKHGLG--HNGAQYGDGLRT--------------ERFTRLY---EDD----WCSTCSSSSSESEEEGFFLGQPIPQPRQPRYQYYA--SDEAA---------FGTR-TKSKQKRGRKGKNCIIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z6W3-1", "uniprot_id": "PRIC1_DROME", "id": "A1Z6W3-1", "name": "Protein prickle", "aln": "MSSLSTGGGAGGSSGGPGGADAAAAPAAGQATVTATGNMEPAMVPRTANLLACKQWWRVCFLYGDQQKYYRQLYSKAAAQRLADANQEPDNARDREYDTVDCDLIAGQLDAVEDADDGIDLGDHSSTPKGGATTAGRPLFPHSSSPRRSKKLLRSLRAHVRGEKLPKNDTTTANESSEVTQRNARVTVLDDPFLFGIDADHLGDLVVRGKRYSTLDATENMARFYAEQEATAQVLEIIEQEEESPEQEAPKPALPPKQKQQRPVPPLPPPPANRVTQDQGTQPAAPQVPLQPLTAGDLQFLNLSLRQRSLPRSMKPFKDAHDISFTFNELDTSAEPEVATGAAQQESNEPISRTPLTQISYLQKIPTLPRHFSPSGQGLATPPALGSGGMGLPSSSSASALYAAQAAAGILPTSPLPLQRHQQYLPPHHQQHPGAGMGPGPGSGAAAGPPLGPQYSPGCSANPKYSNAQLPPPPHHHHQLSPALSTPSPPSLLHHPAGGTSSASAHAPFLGGPHMDMQRQSHSDDDSGCALEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDALGRGNVRQLMSARP---CDGCDDLISTGDIAVFATRLG-PNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSKGEPPTPSDSSGTGMYTTPTPPTQRVRPHPQAPLPARIPSSHASSSPPMSPQQQQQHQATFNQAMYQMQSQQMEAAG---------------------GLVDQSKSYAASDSDAGVVKDLEHGGHMGGGDLTDFSGGRASSTSQNLSPLNSPGDFQPHFLPKPMELQ--------------------------------------RDGVYNFNEMSSNLDAAWSAKPTNSYHLQRQLLEN------PHTASMPELAGKLVAPPAHMQHLSQLHAVSSHQFQQHEYADILHPPPPPPGEIPELPTPNLSVASTALPPELMGSPTHSAGDRSLNTPMSTQSASHAPPHPVSILSGASSSSPMSGEPAKKKGVRFEG----IPDTLPRSRSYSGNGAGTSGGGERERDRDKDKEGGGRHGHGHSSRR---------RRRRKSSSSSSHHRSGSGHRSHSTTRADTYAPAQPLSSSYQGPPSVLQAANLVHESPSRQQREREREREREESE---------------ESD----VCSTCSSSSSS--SEDYMMMYQLPQRRHYGGVRVSYVPNDALAYD---------RKRKPSELGGDKDKNCIIS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . **.* ************:******:*:*: *: :*::******* **: *::*** ************ ** :**::**::** ***:: ****.:: : : *: *. : *::** .:* . . .*:* ** * * ********* :*::.******* *****::*****:*********: ***.**.* **: ********::*:*.* **: ::****: *.: **:*:.**:::* *****: **.* * **** .***::* *:** ** *: ****.:.: .: : ::: . ::. .: : : . : . . . : . : . : : . : .* :. . . . .:. * .. .. :. : . .* : : : * * * . *..: : . . . : . ** .*:**. .: :: :*: : . :.******", "identical_positions": 191, "similar_positions": 146, "identity": "13.54%" }, { "cls_id": "homologset.agr.FB:FBgn0003091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68403-1", "uniprot_id": "KPCB_RAT", "id": "P68403-1", "name": "Protein kinase C beta type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPAAGPPPSEGEE---------------------------------STVR-FARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTER----------------------RGRIYIQAHID-REVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWN----------------------------ETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGSEGNEELRQKFE----------RAKIGQGTKAPEEKTAN----------TISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK-----PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68404-1", "uniprot_id": "KPCB_MOUSE", "id": "P68404-1", "name": "Protein kinase C beta type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPAAGPPPSEGEE---------------------------------STVR-FARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTER----------------------RGRIYIQAHID-REVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWN----------------------------ETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGSEGNEELRQKFE----------RAKIGQGTKAPEEKTAN----------TISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK-----PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05771-1", "uniprot_id": "KPCB_HUMAN", "id": "P05771-1", "name": "Protein kinase C beta type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPAAGPPPSEGEE---------------------------------STVR-FARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTER----------------------RGRIYIQAHID-RDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWN----------------------------ETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGSEANEELRQKFE----------RAKISQGTKVPEEKTTN----------TVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK-----PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY24-1", "uniprot_id": "KPCB_DANRE", "id": "Q7SY24-1", "name": "Protein kinase C beta type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEPAN----SDGEER-------------------------------SAPMRGFARQGALRQKN--VHEVKNHKFIARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKVHTYSSPTFCDHCGSLLYGLIHQGMRCDHCMMNIHKRCVANVPSLCGTDHTER----------------------RGRIQITAEIK-NNVLTVSIKEAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCCLNPTWN----------------------------ETFTFNLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKQGVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGEEGNEELRQKFE----------RAKIGP--SKTDGSSSN----------AISKFDSNGNRDRMKLSDFNFLMVLGKGSFGKVMLAERKGADELFAIKILKKDVVIQDDDVECTMVEKRVLALSGK-----PPFLTQLHSCFQTMDRLYFVMEYINGGDLMYHIQQVGKFKEPHAVFYAAEIAIGLFFLHSKGVIYRDLKLDNVMLDAEGHIKIADFGMCKENMLDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHHVSYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIREHGFFRYMDWEKLEHREVQPPFKPKACG-RDAENFDRFFTRHPPVLTPPDQEVIMNLDQDEFEGFSFINPEFPAMEAQS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20444-1", "uniprot_id": "KPCA_MOUSE", "id": "P20444-1", "name": "Protein kinase C alpha type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADVYPANDSTASQD----------------------------------VANRFARKGALRQKN--VHEVKDHKFIARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINDPSLCGMDHTEK----------------------RGRIYLKAEVT-DEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSNLNPQWN----------------------------ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKAHNQEEGEYYN-------------------------------VPIPEGDEEGNMELRQKFE----------KAKLGPVGNKVISPSED----------RKQ---PSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLNNVMLNSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKQPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05696-1", "uniprot_id": "KPCA_RAT", "id": "P05696-1", "name": "Protein kinase C alpha type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADVYPANDSTASQD----------------------------------VANRFARKGALRQKN--VHEVKDHKFIARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEK----------------------RGRIYLKAEVT-DEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWN----------------------------ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYN-------------------------------VPIPEGDEEGNVELRQKFE----------KAKLGPAGNKVISPSED----------RKQ---PSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17252-1", "uniprot_id": "KPCA_HUMAN", "id": "P17252-1", "name": "Protein kinase C alpha type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADVFPGNDSTASQD----------------------------------VANRFARKGALRQKN--VHEVKDHKFIARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEK----------------------RGRIYLKAEVA-DEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWN----------------------------ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYN-------------------------------VPIPEGDEEGNMELRQKFE----------KAKLGPAGNKVISPSED----------RKQ---PSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PM31-1", "uniprot_id": "A0A8M9PM31_DANRE", "id": "A0A8M9PM31-1", "name": "Protein kinase C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADTQ--SNEQSSSD----------------------------------VANRFARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHELVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDSCDMNVHKQCVMNVPSLCGTDHTER----------------------RGRLYMKIEVI-GDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLIPDPKNETKQKTKTIRSSLNPTWN----------------------------ETFTFKLKPADKDRRLAVEVWDWDRTTRNDFMGSMSFGVSELMKSPVCGWYKMLNQEEGEYYN-------------------------------VPIPDEDDP-DTELRQKFEDETL-EDLEQIAKLGPP-KKNITALDD----------SGSSI-TSSNVDNVRLSDFNFLAVLGKGSFGKVMLAEMKSSDELFAIKILKKDVVIQDDDVECTMVEKRVLAQQDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHKKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENIVEGVTTRTFCGTPDYIAPEIIAYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYSKTLSKEAVSICKGLMTKHPSKRLGCGQEGERDIREHAFFRRIDWDRLANREVQPPFKPKVCG-KGAENFDKFFTRTQPQLTPPDELVIANIDQADFDGFTFVNPQFVHPSLVNTE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AR84-1", "uniprot_id": "A0A8M3AR84_DANRE", "id": "A0A8M3AR84-1", "name": "Protein kinase C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADHL--IQINDSSA----------------------------------GVNRFARKGALRQKN--VHEVKNHKFIARFFKQPTFCSHCTDFIWG---------FGKQGFQCQVCCFVVHKRCHEFVSFSCPGADKGPDTDD-----PRSKHKFKIHSYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVMNVPSLCGTDHTER----------------------RGRIFMKIEVS-GDRLHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPKNETKQKTRTIRSSLNPTWN----------------------------ESFIFKLKASDKERRLSVEVWDWDRTTRNDFMGSMSFGVSELIKAPVSGWYKMLNQEEGEYYN-------------------------------VPIPEENDI-NLELRQKFEACQFNIHLLKKAKLGPG-KKVITPTDH----------RRFSL-PSGNMDKVRLNDFHFLALLGKGSFGKVMLAEMKSTEELYAIKILKKDVVIQDDDVECTMVEKRVLAQREK-----PPFLTQLHSCFQTVDRLYFVMEYINGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHRKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENMYEGMTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLTKEAVSICKGLMTKHPSKRLGCGAEGERDIKEQAFFRRIDWDRLANREIQPPFKPKVCG-KAAENFDKFFTRTQPMLTPPDQLVIANIDQSEFAGFSFINPEFIHPASIHSVV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63318-1", "uniprot_id": "KPCG_MOUSE", "id": "P63318-1", "name": "Protein kinase C gamma type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGLGPGGGDSEGGP-----------------------------------RPLFCRKGALRQKV--VHEVKSHKFTARFFKQPTFCSHCTDFIWG---------IGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDD-----PRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTER----------------------RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWN----------------------------ETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYN-------------------------------VPVAD---ADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSP--------TDSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCG-RSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63319-1", "uniprot_id": "KPCG_RAT", "id": "P63319-1", "name": "Protein kinase C gamma type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGLGPGGGDSEGGP-----------------------------------RPLFCRKGALRQKV--VHEVKSHKFTARFFKQPTFCSHCTDFIWG---------IGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDD-----PRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTER----------------------RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWN----------------------------ETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYN-------------------------------VPVAD---ADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSP--------TDSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCG-RSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05129-1", "uniprot_id": "KPCG_HUMAN", "id": "P05129-1", "name": "Protein kinase C gamma type", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGLGPGVGDSEGGP-----------------------------------RPLFCRKGALRQKV--VHEVKSHKFTARFFKQPTFCSHCTDFIWG---------IGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDD-----PRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTER----------------------RGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWN----------------------------ETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYN-------------------------------VPVAD---ADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSP--------TDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCG-RSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQZ0-1", "uniprot_id": "A0A8M1QQZ0_DANRE", "id": "A0A8M1QQZ0-1", "name": "Protein kinase C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTPVSPSPSLSPLALSSPSPSSSPLPSPLS-------------------------PPPRLPVFQRKGALKHKR--VIEVKDHQFTARFFKQPTFCSHCTDFIWG---------IGKQGFQCQVCSFVVHKRCHEFVTFTCPGAITAPKPED-----LKSKHKFKVHTYSSPTFCDHCGSLLYGLIHQGMKCGCCDMNVHKRCESSVPSLCGQDHTEK----------------------RGRIRLTVRGE-KEDIYITVHEALNLIPMDPNGLSDPYVKLKLIPDPKSHSKQKTKTIRSTLNPIWN----------------------------ESFTFSVRGRQWDRRLSVEVWDWDRTSRNDFMGALSFGVSEIFRRSVSGWFKLLNQDEGEYYN-------------------------------IPVPDPDLQVPEEILMPSIP----------PTPSPVTTPVPAVTPPA--------LSPAPAVLHTGKGHIGLHDFNFLMVLGKGSFGKVLLAEEKGSERLFAIKMLKKDVLFQDEDTESAMVERRVLALSGR-----PHFLTSLYCAFQTEDRLYYVMEYVNGGDLMFHIQIVGKFKEPHAAFYAAEIAVGLFFLHNKGIIYRDLKLDNVLLDSEGHIKIADFGMCREGMMEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWSYGVLLYEMLAGQPPFDGIDEEELFQSIMEQSVSYPKSLSREAVAICKGLLTKNPAKRLGGGEDAERELREHPFFRWIDWDRLERLEIQPPFKPRSGG-KKGENFDKFFTSTSSALTPSDPDVLAAINQEEFQDFTFMNSEFPPSPLTAV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05130-1", "uniprot_id": "KPC1_DROME", "id": "P05130-1", "name": "Protein kinase C, brain isozyme", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEGSDNNGDPQQQGAEGEAV-------------------------GENKMKSRLRKGALKKKN--VFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKRCHEYVTFICPGKDKGIDSDS-----PKTQHNFEPFTYAGPTFCDHCGSLLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTER----------------------RGRIYLEINVK-ENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWN----------------------------ETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGEYYN-------------------------------VPCAD-DEQDLLKLKQKPS------------QKKPMVMRSDTNTHT-----------------SSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEK-----PPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQSEFVGFSYMNPEYVFSP-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRY------------TGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKT---KHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPS-VLTTSQQEEFRGFSFMPDDLDL---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:**: :: : : :.* * : * : *::* **: *:*** * :: *::*: * * . . . : *.* : ...:* *** :* *: :*. * : * :* *.:** . .:: . : *: *: .. . . . :*:: : :. : .: : . * : : . : : : . : . *: : .*:.** : . . . : :* :: :****.****:*:. :.::.* *:*:**** :.*:.* :.: *::*: : **..*:. *** :*:::.**:: *****:::* ::. * *****: .* ::: .*::******:*::* .:**:**:*:*:*:: : . * ******:::****: * * ::****::*****:** *.**.* **:*:* :* . *. :: * :*::**.* **** * : . *** :::: : . .: **: *. . . *:: ** *** .: :* :* .*:: : ", "identical_positions": 160, "similar_positions": 191, "identity": "13.52%" }, { "cls_id": "homologset.agr.FB:FBgn0003093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16054-1", "uniprot_id": "KPCE_MOUSE", "id": "P16054-1", "name": "Protein kinase C epsilon type", "aln": "---------------------------------------------------------------------------------------------------------------------MVVFNGLLKIKICEAVSLKPTAWSLRH-------------------AVGPRPQTFLLDPYIALNVDDSRIGQTATKQKTNSP--------------------------------------------------------AWHDEFVTDVCNGRKIELAVFHDAPIGYD----DFVANCTIQFEELLQNG--SRHFEDWIDLEPEGKVYVIIDLSGSSGEAP--------------------------------------------KDNEERVFRERMRPRKRQGAVRRR---VHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLK--KQE-TPDEVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLAAGAES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQPASGNSPSEDDRSKSAPTSPCDQELKELENNIRKALSFDNRGEEHRASSA-TDGQLASPGENGEVRPGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGIMNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPILTLVDEAIIKQINQEEFKGFSYFGEDLMP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09216-1", "uniprot_id": "KPCE_RAT", "id": "P09216-1", "name": "Protein kinase C epsilon type", "aln": "---------------------------------------------------------------------------------------------------------------------MVVFNGLLKIKICEAVSLKPTAWSLRH-------------------AVGPRPQTFLLDPYIALNVDDSRIGQTATKQKTNSP--------------------------------------------------------AWHDEFVTDVCNGRKIELAVFHDAPIGYD----DFVANCTIQFEELLQNG--SRHFEDWIDLEPEGKVYVIIDLSGSSGEAP--------------------------------------------KDNEERVFRERMRPRKRQGAVRRR---VHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLK--KQE-TPDEVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLAAGAES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQPASGNSPSEDDRSKSAPTSPCDQELKELENNIRKALSFDNRGEEHRASSS-TDGQLASPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSGFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHSKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKMKPPFKPRIKTKRDVNNFDQDFTREEPILTLVDEAIVKQINQEEFKGFSYFGEDLMP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02156-1", "uniprot_id": "KPCE_HUMAN", "id": "Q02156-1", "name": "Protein kinase C epsilon type", "aln": "---------------------------------------------------------------------------------------------------------------------MVVFNGLLKIKICEAVSLKPTAWSLRH-------------------AVGPRPQTFLLDPYIALNVDDSRIGQTATKQKTNSP--------------------------------------------------------AWHDEFVTDVCNGRKIELAVFHDAPIGYD----DFVANCTIQFEELLQNG--SRHFEDWIDLEPEGRVYVIIDLSGSSGEAP--------------------------------------------KDNEERVFRERMRPRKRQGAVRRR---VHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLK--KQE-TPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQPASGSSPSEEDRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASS-PDGQLMSPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PMR2-1", "uniprot_id": "A0A8M9PMR2_DANRE", "id": "A0A8M9PMR2-1", "name": "Protein kinase C", "aln": "---------------------------------------------------------------------------------------------------------------------MVVFNGLLKIKICEALDLKPTAWSLRH-------------------AVGPKTQTFLLDTYIALNVDDFRVGQTSTKQKTNSP--------------------------------------------------------AWHDELVTEVHDGRKIELSVFHDAPIGYD----DFVANCTIQFEELLHNG--SKHFEDWIDLEPEGKVFVIIDLSGSSSEAGG-------------------------------------------CENEERVFRERMRPRKRQGAVRRR---VHQVNGHKFMATYLRQPTYCSHCRDFIWGVLGKQGYQCQVCTCVVHKRCHELIITKCAGLK--KQEDTAEEVGSQRFSVNMPHKFRIHNYKVLTFCDHCGSLLWGLLRQGLQCKVCKMNVHKRCEINVAPNCGVDARGIAKVLSDLGVTPDKLSGSVQRRKKISQGPD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PHPLPISPLLEEDRCKSAPTSPCDQDIKDLEN-IRKALSFDHRSEEMKQASEGVSEETGEARENGEVKTVQAKRMMLEDFSFIKVLGKGSFGKVMLAELRGTDEVFAVKVLKKDVILQDDDVDCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLHHNGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILDGITTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKSPSKRLGCVVSQGLEEAIKVHPFFKDIDWVLLEQRKVKPPFKPRIKTKRDVNNFDQDFTREEPVLTPVEDAIIKQINQEEFKGFSYFGEETLS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23298-1", "uniprot_id": "KPCL_MOUSE", "id": "P23298-1", "name": "Protein kinase C eta type", "aln": "-----------------------------------------------------------------------------------------------------------------MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRH-------------------SLFKKG-HQLLDPYLTVSVDQVRVGQTSTKQKTNKP--------------------------------------------------------TYNEEFCANVTDGGHLELAVFHETPLGYD----HFVANCTLQFQELLRTAGTSDTFEGWVDLEPEGKVFVVITLTGSFTEAT---------------------------------------------LQRDRIFKHFTR--KRQRAMRRR---VHQVNGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQN--NINKVDAKIAEQRFGINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNIS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTS--------------KLISRSTLRRQGKEGSK----------EGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARN--HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLT-QGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64617-1", "uniprot_id": "KPCL_RAT", "id": "Q64617-1", "name": "Protein kinase C eta type", "aln": "-----------------------------------------------------------------------------------------------------------------MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRH-------------------SLFKKG-HQLLDPYLTVSVDQVRVGQTSTKQKTNKP--------------------------------------------------------TYNEEFCTNVSDGGHLELAVFHETPLGYD----HFVANCTLQFQELLRTAGTSDTFEGWVDLEPEGKVFVVITLTGSFTEAT---------------------------------------------LQRDRIFKHFTR--KRQRAMRRR---VHQVNGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQN--NINKVDAKIAEQRFGINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNIS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTS--------------KLISRSTLRRQGKEGSK----------EGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARN--HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLT-QGGEHEILRHPFFKEIDWVQLNHRQLEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24723-1", "uniprot_id": "KPCL_HUMAN", "id": "P24723-1", "name": "Protein kinase C eta type", "aln": "-----------------------------------------------------------------------------------------------------------------MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRH-------------------SLFKKG-HQLLDPYLTVSVDQVRVGQTSTKQKTNKP--------------------------------------------------------TYNEEFCANVTDGGHLELAVFHETPLGYD----HFVANCTLQFQELLRTTGASDTFEGWVDLEPEGKVFVVITLTGSFTEAT---------------------------------------------LQRDRIFKHFTR--KRQRAMRRR---VHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQN--NINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNIS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTS--------------KLVSRSTLRRQGKESSK----------EGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARN--HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLT-QGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q5P7-1", "uniprot_id": "A0A2R8Q5P7_DANRE", "id": "A0A2R8Q5P7-1", "name": "Protein kinase C", "aln": "----------------------------------------------------------------------------------------------------------------------MKFNGLMKLRIGEAVDLKPTTSSTRH-------------------TFSRKM---QLDPYIVVKVDNVQLGRTAIKTKTDKP--------------------------------------------------------TFNEEFTKTISNGVELELAVFHSARLGYD----TFVANYRIQLEDLITPSNTNQTFEGWVNLEPEGSVYIFITLTGSFTDDE--------------------------------------------AVNIVKTHKEFVR---KKVLKRRK---VHQIYGHKFMATFLPQPTFCYHCKNFIWGVIGKQGYQCQVCTCVVHKRCHALVVTECPRMR--KDANEGQRQG---FSINLPHQFKEHNYKVPTYCNHCGSLLYGLVKQGLHCKICKMNIHKRCEQNVAPNCGVDNAELASKLSEIGLLN-TISK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKS-----------------QGSLHMSSVRSQSSTTSI---------ETTEEESDEEAVKVCLEDFSFLQVLGKGSFGKVMLARLKSDHRVFAVKMLKKDVILQEDDVEATMTEKRVLTLAHQ--HPFLTQLYYCFQTTERLFFVMEFVNGGDLMFHIQKCRRFDEPRAQFYAAEVTSALKFLHSKGIIYRDLKLDNILLDRDGHCKLADFGMCKEEIFNGKLTSTFCGTPDYIAPEILQEELYGVSVDWWALGVLLYEMLSGHAPFEAETEDELFECILKDEIIYSSWLSYEAEDILKGLLTRDPACRLGCIDNDGGEEAITAHAFFTGLDWEKLYRREITPPFTPRINSIEDVNNFDPDFTQEDPCLTPIEESLFP-FHQDGFKDFSYIAPELRHN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13678-1", "uniprot_id": "KPC3_DROME", "id": "P13678-1", "name": "Protein kinase C", "aln": "-----------------------------------------------------------------------------------------------------------------------MFTGKLQIKVCEASGLRPTDFQKRHNL-----------------TFGKLADEQLIDPYVSIDVDESHFDRATTRPKTFDP--------------------------------------------------------VWNEQFVHDVTNVSNINLTVFHDAALPPD----DFVANCIISFEDLMQSE--TAVQDLWVNLEPQGKIHVIIELKNRTDKAKAE-------------------------------------AVVEHTVAVNKEFKERAGFNRRRGAMRRR---VHQVNGHKFMATFLRQPTFCSHCREFIWG-IGKQGYQCQVCTLVVHKKCHLSVVSKCPGMRDEQPAKVEMVPAGQRFNVNLPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCETCGMNVHKRCQKNVANTCGINTKQMAEILSSLGISPDKQQPRRSKYLNQQGGED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYGASLGADGDGAPGQSFRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGGVGATGETRPGKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAAN--HPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTG---DENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQDEFAGFSFVNPKFGPERKVY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRY----TGFQCQDCKFLCHKKCYTNVVTKCIAKT-----STDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQN-QRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGP--RDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPS-VLTTSQQEEFRGFSFMPDDLDL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::: : * : :. * :.** :. : . . : ::: : . .::::*:... :: : : . : *:: . . . . :. :: .: :.: **:*: . : : * :* :*: *:*** *. : **:*: ::: * :. .:**:* . : .:* *** :* :: :*. * : * :* *. **:. . * : . . . : : :* :::*****.****:*:. : : *:*:**** *:*:.*::.: :**::: ** : **:** *. .*** :*::*.**::.*****:::*. :::. *: *****: ** ::* :*:*******:*:** :** *:**:*:**: : * *:******:::*****:* * :*****:***:*:*: :.**..: **::*:.*: *: :*. : : *::.::*:.* ***. . : ..** ::: : . .: **: *.::. .*.. *: :* * ** : . . :*: * .**:. . ", "identical_positions": 161, "similar_positions": 213, "identity": "13.77%" }, { "cls_id": "homologset.agr.FB:FBgn0003116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BIW1-1", "uniprot_id": "PRUN1_MOUSE", "id": "Q8BIW1-1", "name": "Exopolyphosphatase PRUNE1", "aln": "-------MEDYLQDCRAALQ-----------------DSRPLHVVLGNEACDLDSMVSALALAFY--------LTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIPEPALIFRDEID--LLALHQAGQLTLILVDHHILPKSDAALEEAVAEVLDHRPIEQ------KYCPPCHVSVEL-VGSCATLVTERILQGAPETLDRQT--AALLHGTIILDCVNMDTNIGKATPKDSKYVEELEALFP-DLPKR-----KDIFDSLQKAKFDVSGLTTEQMLRKDQKTVYRQG-----TKVAISAIYMDLKAFLQRTD----LFTDLSSFCHDHSYDALVAMTIFFNTQNEPVRQLAIFCP--HEALRMTICGILERSTSPPLKLTPIPSTSPNLQ--AYHQGNTQVSRKKLLPVLQEALSAYLDSAKMASGQSEVAVGMSREQVDKDLDKASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKFSAEAVFEKCSQISLSQSARACTSNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYG3-1", "uniprot_id": "PRUN1_RAT", "id": "Q6AYG3-1", "name": "Exopolyphosphatase PRUNE1", "aln": "-------MEDYLQDCRAALQ-----------------ESRPLHVVLGNEACDLDSMVSALALAFY--------LTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIAESALIFRDEID--LLALHQAGQLTLILVDHHMLPKSDAALEEAVAEVLDHRPIEQ------KYCPPCHVSVEL-VGSCATLVAERILQGAPETLDRQT--AALLHGTIILDCVNMDAKIGKATLKDNEYVEKLEALFP-DLPKR-----KDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQG-----TKVAVSAVYMDLEAFLQRSG----LLSDLSAFCQDHSYDALVAMAIFFNTHNEPVRQLAIFCP--HEALRMTICGVLEQSTSPALKLTPIPSISAHLQ--AYLQGNTQVSRKKLLPVLQEALSAYLDSMRTPAGQLEAALGMSREQADKELDKASNSLIAGLSQDDEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTRACPSNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TP1-1", "uniprot_id": "PRUN1_HUMAN", "id": "Q86TP1-1", "name": "Exopolyphosphatase PRUNE1", "aln": "-------MEDYLQGCRAALQ-----------------ESRPLHVVLGNEACDLDSTVSALALAFY--------LAKTTEAEEVFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEID--LHALYQAGQLTLILVDHHILSKSDTALEEAVAEVLDHRPIEP------KHCPPCHVSVEL-VGSCATLVTERILQGAPEILDRQT--AALLHGTIILDCVNMDLKIGKATPKDSKYVEKLEALFP-DLPKR-----NDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQG-----VKVAISAIYMDLEAFLQRSN----LLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLAIFCP--HVALQTTICEVLERSHSPPLKLTPASSTHPNLH--AYLQGNTQVSRKKLLPLLQEALSAYFDSMKIPSGQPETAD-VSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18399-1", "uniprot_id": "O18399_DROME", "id": "O18399-1", "name": "", "aln": "-----MCFLRFLAQARGTLGRHLAEASPVAWAAAPDVSGRKLHLVMGNESCDLDSAVSAVTLAFV--------YAQR-HREHDYVPILNIPRRDYPLKTEVGHLFVKCGIAEPVLLFRDDIP--REVVQDVN---VILVDHHVSP-----LAPNVTEILDHRPLEDSSPSFKQLPTLCQLDIDASVGSCATLVAQRYLAED-QPRSTSV--AQLLHATIVLDTINFAPAAKRYGPKDEAMVQKLESELNRKDAQR-----SSLFDELVAARADISKLTLTEVLRKDMKVLQTDR-----QVVPLAGMPILVRDFVEKSG----AEKAVREFGVESNLLVILGMYVSP-ADGQVQRDLALISLSGQGQFVQRVQQALMESNDPKLELRPHEVDTRFMGGCFLRQHNVQATRKHILPIVKRALLEWEADHACDCD-----------------------------------------------------------EVYFFKEKPQLGLS----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38698-1", "uniprot_id": "PPX1_YEAST", "id": "P38698-1", "name": "Polyphosphatase", "aln": "MSPLRKTVPEFLAHLKSLPIS-------------KIASNDVLTICVGNESADMDSIASAITYSYCQYIYNEGTYSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEELFFIEDLKSLKQNVSQGTELNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQ-------KHLDAEPRIVKVSGSCSSLVFNYWYEKLQGDREVVMNIAPLLMGAILIDTSNMRRKVEESDKLAIERCQAVLSGAVNEVSAQGLEDSSEFYKEIKSRKNDIKGFSVSDILKKDYKQFNFQGKGHKGLEIGLSSIVKRMSWLFNEHGGEADFVNQCRRFQAERGLDVLVLLTSWR-KAGDSHRELVILGD-------SNVVRELIERVSDKLQLQLFGGN-LDGGVAMFKQLNVEATRKQVVPYLEEAYSNLEE------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* :. .. * : :***:.*:** .**:: :: :: . :*:::* * : .*: : ..: : * * *:* ::: : : ***:: . *. ::**: .. : ***::** : . * ** .:*::* *: . : : : . . : ..::..: : *:. :: ::*:** * . : : ::.: : :.:. . * . .:: : .: *:*.:: : * . . *:* * *.:.:**:::* ::.* ", "identical_positions": 52, "similar_positions": 116, "identity": "10.08%" }, { "cls_id": "homologset.agr.FB:FBgn0003117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNA5-1", "uniprot_id": "A0ABZ3NNA5_RAT", "id": "A0ABZ3NNA5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MYQSLALAQSPGQ---GTYAD--SGPFLHSSG--------AGSPVFVAPTRVPSMLPYLPS------CEPGSQ----PPALAAHSSWTQAVSAESSAFG----------SGSPHPPATHPPGATAFPFAHSP-------------SGSGSGGSAGVRDGAAFQSALLARE-QYPTA-LGRPMSASYPTTY----------PAYVSPDVAPSWTSGPFDSSILHGLQGRPGGLPGRRTTFVPDFLEEFPGEGRECVNCG-----ALSTPLWRRDGTGHYLCNAC---GLYHKMNGVNRPLVRPQKRLLSFTAPEAPKSRVPNFWAHPSLLAPQSSSRRSGLCCSNCHTATTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANSTASSPTLLNTESSATTLK----------AES--SLASPGCAGPTITSQASSPADESLASSHLEFKFEP-------EDFVFTSSSLSPQAGLSG--VLRQEAWCALALA-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97489-1", "uniprot_id": "GATA5_MOUSE", "id": "P97489-1", "name": "Transcription factor GATA-5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MYQSLALAQSPGQ---GTYAD--SGAFLHSSG--------TGSPVFVAPTRMPSMLPYLPS------CEPGSQ----APALAAHSSWTQAVAADSSAFG----------SGSPHPPAAHPPGATTFPFAHSP-------------PGSGSGGSAGVRDGGAFQGALLARE-QYPTP-LGRPMGASYPTTY----------PAYMSSDVAPSWTSGAFDSSILHGLQARPGGLPGRRTSFVPDFLEEFPGEGRECVNCG-----ALSTPLWRRDGTGHYLCNAC---GLYHKMNGVNRPLVRPQKRLS--------------------------SSRRSGLCCSNCHTATTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANTTASSPTLLNSESSATTLK----------AES--SLASPVCAGPTITSQASSPADESLASSHLEFKFEP-------EDFAFTSSSMSPQAGLSG--VLRQETWCALALA-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWX5-1", "uniprot_id": "GATA5_HUMAN", "id": "Q9BWX5-1", "name": "Transcription factor GATA-5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MYQSLALAASPRQ---AAYAD--SGSFLHAPG--------AGSPMFVPPARVPSMLSYLSG------CEPSPQ----PPELAARPGWAQTATADSSAFG----------PGSPHPPAAHPPGATAFPFAHSP-------------SGPGSGGSAGGRDGSAYQGALLPRE-QFAAP-LGRPVGTSYSATY----------PAYVSPDVAQSWTAGPFDGSVLH-------GLPGRRPTFVSDFLEEFPGEGRECVNCG-----ALSTPLWRRDGTGHYLCNAC---GLYHKMNGVNRPLVRPQKRLS--------------------------SSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSK----------AKP--SLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEP-------EDFAFPSTAPSPQAGLRG--ALRQEAWCALALA-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08369-1", "uniprot_id": "GATA4_MOUSE", "id": "Q08369-1", "name": "Transcription factor GATA-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MYQSLAMAANHGPPP-GAYEAGGPGAFMHSAG-------AASSPVYVPTPRVPSSVLGLSY-----LQGGGSA----AAAGTTSGGSSGAG-PSGAGPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAA-----AAAAREAAAYGSGGGAAGAGLAGRE-QYGRPGFAGSYSSPYPAYMADVG------ASWAAA---AAASAGPFDSPVLHSLPGRANPG----RHPNLDMFDDFS-EGRECVNCG-----AMSTPLWRRDGTGHYLCNAC---GLYHKMNGINRPLIKPQRRLS--------------------------ASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPAG-ETLPPSSGASSGNSSNATS----------SSSSSEEMRPIKTEPGLSSHYGHSSSMSQTFST--VSGHGPSIHPVLSALKLSPQGYASPVTQTSQASSKQDSWNSLVLADSHGDIITA----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46152-1", "uniprot_id": "GATA4_RAT", "id": "P46152-1", "name": "Transcription factor GATA-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MYQSLAMAANHGPPP-GAYEAGGPGAFMHSAG-------AASSPVYVPTPRVPSSVLGLSY-----LQGGGSG----AASGATSGGSSGAG-PSGAGPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAA-----AAAAREAAAYSSSGGAAGAGLAGRE-QYGRPGFAGSYSSPYPAYMADVG------ASWAAA---AAASAGPFDSPVLHSLPGRANPA----RHPNLDMFDDFS-EGRECVNCG-----AMSTPLWRRDGTGHYLCNAC---GLYHKMNGINRPLIKPQRRLS--------------------------ASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPPG-ESLPPSSGASS-NSSNATS----------SSSSSEEMRPIKTEPGLSSHYGHSSSMSQTFST--VSGHGSSIHPVLSALKLSPQGYPSPVTQTSQASSKQDSWNSLVLADSHGDIITA----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43694-1", "uniprot_id": "GATA4_HUMAN", "id": "P43694-1", "name": "Transcription factor GATA-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MYQSLAMAANHGPPP-GAYEAGGPGAFMHGAG-------AASSPVYVPTPRVPSSVLGLSY-----LQGGGAG----SASGGASGGSSGGA-ASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAA-----AAAAREAAAYSSGGGAAGAGLAGRE-QYGRAGFAGSYSSPYPAYMADVG------ASWAAA---AAASAGPFDSPVLHSLPGRANPAA---RHPNLDMFDDFS-EGRECVNCG-----AMSTPLWRRDGTGHYLCNAC---GLYHKMNGINRPLIKPQRRLS--------------------------ASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASS-NSSNATT----------SSS--EEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61169-1", "uniprot_id": "GATA6_MOUSE", "id": "Q61169-1", "name": "Transcription factor GATA-6", "aln": "MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDAEAVAGPPGRSLLLSPYASHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGP---AAYDG-APGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLSGLPY-----LQGAGSGPSNHAGGAGAHPGWSQAS-ADSPPYG-GGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGTGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHP----TYSPYMAAPLTPAWPAGPFETPVLHSLQGRAGAPLPVPRGPSTDLLEDLS-ESRECVNCG-----SIQTPLWRRDGTGHYLCNAC---GLYSKMNGLSRPLIKPQKRVP--------------------------SSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSSGSVPMTPTSSSS-NSDDCTK----------NTS--PSTQATTSGVGASVMSAVGENANPENSDLKYSGQ--------DGLYIG-VSLSSPAEVTS--SVRQDSWCALALA-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46153-1", "uniprot_id": "GATA6_RAT", "id": "P46153-1", "name": "Transcription factor GATA-6", "aln": "MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDTEAVAGPPGRSLLLSPYTSHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGP---AAYDG-APGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPY-----LQGAGSGPSNHAGGAGAHPGWPQAS-ADSPPYG-GGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGAGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHP----TYSPYMGAPLTPAWPAGPFETPVLHSLQSRAGAPLPVPRGPSADLLEDLS-ESRECVNCG-----SIQTPLWRRDGTGHYLCNAC---GLYSKMNGLSRPLIKPQKRVP--------------------------SSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSS--VPMTPTSSSS-NSDDCTK----------NTS--PPTQSTASGVGASVMSAVGESANPENSDLKYSGQ--------DGLYIG-VSLSSPAEVTS--SVRQDSWCALALA-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92908-1", "uniprot_id": "GATA6_HUMAN", "id": "Q92908-1", "name": "Transcription factor GATA-6", "aln": "MALTDGGWCLPKRFGAAGADASDSRAFPAREPSTPPSPISSSSSSCSRGGERGPGGASNCGTPQLDTEAAAGPPARSLLLSSYASHPFGAPHGPSAPGVAGPGGNLSSWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAPEQPEEMYQTLAALSSQGP---AAYDG-APGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYH----LQGSGSGPANHAGGAGAHPGWPQAS-ADSPPYGSGGGAAGGGAAGPGGAGSAAAHVSARFPYSPSPPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHPSPYSPYVGAPLTPAWPAGPFETPVLHSLQSRAGAPLPVPRGPSADLLEDLS-ESRECVNCG-----SIQTPLWRRDGTGHYLCNAC---GLYSKMNGLSRPLIKPQKRVP--------------------------SSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSS-NSDDCSK----------NTS--PTTQPTASGAGAPVMTGAGESTNPENSELKYSGQ--------DGLYIG-VSLASPAEVTS--SVRPDSWCALALA-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52168-1", "uniprot_id": "PNR_DROME", "id": "P52168-1", "name": "GATA-binding factor A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MGILLSDGD---STSDQQSTRDYPHFSG--------DYQNVTLSAASASTSASASAT-------HVAAVKMYHSSAVAAYTDLAAAGSAASAGVG----------VGVSGYHQQAVNAPVYVPSNRQYN-------------HVAAHFGSAAAQNAWTTEGFGSAHAQFYSPNAAVMMGSWRSAYDPSGFQR----------------------------------------SSPYESAMDFQFGEGRECVNCG-----AISTPLWRRDGTGHYLCNAC---GLYHKMNGMNRPLIKPSKRLVS-----------------------ATATRRMGLCCTNCGTRTTTLWRRNNDGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTLEAIKECKEEHDLKPSLSLERHSLSKLHTDMKSGTSSSSTLMGHHSAQQQQQQQQQQQQQQQQQQQQSAHQQCFPLYGQTTTQQQHQQHGHSMTSSSGQAHLSARHLHGAAGTQLYTPGSSSGGGSASAYTSHSAETPALSNGTPSPHYQHHHHLGGTHGHHVTAAAAHHHFHAAAAVAAYGVKTEASATNYDYVNNCYFGGTFGALGGAATTTAMAGGAASELAGYHHQHNVIQAAKLMATS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43574-1", "uniprot_id": "GAT1_YEAST", "id": "P43574-1", "name": "Transcriptional regulatory protein GAT1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MHVFFPLLFRPSPVLFIACAYIYIDIYIHCTR-------CTVVNITMSTNRVPNLDPDLNLNKEIWDLYSSAQKILPDSNRILNLSWRLHNRTSFHRINRIMQHSNSIMDFSASPFASGVNAAGPGNNDLDDTDTDNQQFFLSDMNLNGSSVFENVFDDDDDDDDVETHSIVHSDLLNDMDSASQRASHNASGF------PNFLDTSCSSSFDDHFIFTNNLPFLNNNSINNNHSHNSSHNNNSPSIANNTNANTNTNTSASTNTNSPLLRRNPSPSIVKPGS---RRNSSVRKKKPALKKIKSSTSVQSSATPP----------------SNTSSNPDIKCSNCTTSTTPLWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDIIKKRQRSSTKINNNITPPPSSSLNPGAAGKKKNYTASVAASK----------RKNSLNIVAPLKSQDIPIPKIASPSIPQYLRSNTRHHLSSS-----VPIEAETFSSFRPDMNMTMNMNLHNASTSSFNNEAFWKPLDSAIDHHSGDTNPNSNMNTTPNGNLSLDWLNLNL---------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42944-1", "uniprot_id": "GZF3_YEAST", "id": "P42944-1", "name": "Protein GZF3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MASQATTLRGYNIRKRDNVFEPKSSENLNSLNQSEEEGHIGRWPPLGYEAVSAEQKSAVQLRESQAG------ASISNNMNFKANDKSFSTSTAGRMSPDTNSLHHILPKNQVKNNGQTMDANCNNNVSNDANVPVCKNCLTSTTP-----LWRRDEHGAMLCNACGLFLKLHGKPRPISLKTDVIKSRNRKSNTNHAHN-----LDNFRNQTLIAELKGDCNIESSGRKANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESK----ERSDSHLSATKLEVLMSGDCSRPNLKPKLPKQDTAIYQEKLLTFP-----------------------SYTDVKEYSNSAHQSAFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNP---------SEVPNQIRSTMSSPDIISAKRNDPAPLSFHMASINDMLETRDRAISNVKTETTPPHFIPFLQSSKAPCISKANSQSISNSVSSSDVSGRKFENHPAKDLGDQLSTKLHKEEEIIKLKTRINELELVTDLYRRHINELDGKCRALEERLQRTVKQEGNKGG-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . . . . . . . . . : . .: . .: : . : . .:: : . : : . *: : .: * . *. . : . . .. . . . . . : ", "identical_positions": 3, "similar_positions": 50, "identity": "0.37%" }, { "cls_id": "homologset.agr.FB:FBgn0003118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14921-1", "uniprot_id": "ETS1_HUMAN", "id": "P14921-1", "name": "Protein C-ets-1", "aln": "-----------------------------------------------------MKAAVDLKPTLTIIK-------------------------------------------TEKVDLELFP-------------SPDMECADVP----LLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFC-MNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPY---------------------QVNGVNPAYPESRYTSDYFIS---------------YGIEHAQCVPPSEFSEP-------SFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFES-IESYDSCDRLTQSWSSQ----------------SSFNSLQRVPSY------------------------DSFDSEDYPAALPNHKP------------------KGTFKDYVRDRAD-------------------------------------------------------LNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41156-1", "uniprot_id": "ETS1_RAT", "id": "P41156-1", "name": "Protein C-ets-1", "aln": "-----------------------------------------------------MKAAVDLKPTLTIIK-------------------------------------------TEKVDLELFP-------------SPDMECADVP----LLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFC-MNGAALCALGKECFLELAPDFVGDILWEHLEILQKEDVKPY---------------------QVNGVNPTYPESRYTSDYFIS---------------YGIEHAQCVPPSEFSEP-------SFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQTDYFAIKQEVLTPDNMCMGRASRGKLGGQDSFES-IESYDSCDRLTQSWSSQ----------------SSFNSLQRVPSY------------------------DSFDSEDYPAALPNHKP------------------KGTFKDYVRDRAD-------------------------------------------------------LNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27577-1", "uniprot_id": "ETS1_MOUSE", "id": "P27577-1", "name": "Protein C-ets-1", "aln": "-----------------------------------------------------MKAAVDLKPTLTIIK-------------------------------------------TEKVDLELFP-------------SPDMECADVP----LLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFC-MSGAALCALGKECFLELAPDFVGDILWEHLEILQKEDVKPY---------------------QVNGANPTYPESCYTSDYFIS---------------YGIEHAQCVPPSEFSEP-------SFITESYQTLHPISSEELLSLKYENDYPSVILQDPLQTDTLQTDYFAIKQEVLTPDNMCLGRASRGKLGGQDSFES-VESYDSCDRLTQSWSSQ----------------SSFNSLQRVPSY------------------------DSFDYEDYPAALPNHKP------------------KGTFKDYVRDRAD-------------------------------------------------------LNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDAD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZS11-1", "uniprot_id": "A0A8I5ZS11_RAT", "id": "A0A8I5ZS11-1", "name": "", "aln": "-----------MSPARPALGSPGPWEASTGHVQVGMNDFGIKNMDQVAPVANSFRGTLKRQPAFDTFDGS---------------------------------LFAVLPSLSEEQTLQEVPTG-------LDSVSHDSATCELP----LLTPCSKAVMSQALKATFSGFHKEQRRLGIPKNPWLWNEQQVCQWLHWATNEFSLVNVNLQRFG-MNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQE-----------------------KTEDQYEENSHLNAVPHWINS---------------NTLGFGVEQAPYGMQAP-------SYLKDGLLDGMCPPSATPAALGSEQELQMLPKS---RLNTVSVNYCSISQDFPG-GNLNLLNSSSGKPKEHDSPENGGDSFESSDSLLRSWNSQ----------------SSLLDVQRVPSF------------------------ESFE-EDCSQSLCLSKP------------------TMSFKDYIQERSDP------------------------------------------------------VEQGKPVIPAAVLAG----FTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15037-1", "uniprot_id": "ETS2_MOUSE", "id": "P15037-1", "name": "Protein C-ets-2", "aln": "-----------------------------------MNDFGIKNMDQVAPVANSFRGTLKRQPAFDTFDGS---------------------------------LFAVLPSLSEDQTLQEVPTG-------LDSVSHDSASCELP----LLTPCSKAVMSQALKATFSGFQKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLHQFG-MNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQE-----------------------KTEDQYEENSHLNAVPHWINS---------------NTLGFSMEQAPYGMQAP-------NYPKDNLLDSMCPPSATPAALGS--ELQMLPKS---RLNTVNVNYCSISQDFPS-SNVNLLNNNSGKPKDHDSPENGGDSFESSDSLLRSWNSQ----------------SSLLDVQRVPSF------------------------ESFE-EDCSQSLCLSKL------------------TMSFKDYIQERSDP------------------------------------------------------VEQGKPVIPAAVLAG----FTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15036-1", "uniprot_id": "ETS2_HUMAN", "id": "P15036-1", "name": "Protein C-ets-2", "aln": "-----------------------------------MNDFGIKNMDQVAPVANSYRGTLKRQPAFDTFDGS---------------------------------LFAVFPSLNEEQTLQEVPTG-------LDSISHDSANCELP----LLTPCSKAVMSQALKATFSGFKKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLQRFG-MNGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQE-----------------------KTEDQYEENSHLTSVPHWINS---------------NTLGFGTEQAPYGMQTQ-------NYPKGGLLDSMCP-ASTPSVLSSEQEFQMFPKS---RLSSVSVTYCSVSQDFPG-SNLNLLTNNSGTPKDHDSPENGADSFESSDSLLQSWNSQ----------------SSLLDVQRVPSF------------------------ESFE-DDCSQSLCLNKP------------------TMSFKDYIQERSDP------------------------------------------------------VEQGKPVIPAAVLAG----FTGSGPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51023-1", "uniprot_id": "PNT_DROME", "id": "P51023-1", "name": "ETS-like protein pointed", "aln": "MELAICKTDLSATKFMLPPALPSSAAIGSSSAVASTASHFLDKAAHELFQLNAINGHLFKSPASSHLNSVGSPSILSQLNGIGNSGNHSGQVSTMRLKKNRKVTFLSSLVESKNIFIKEEPIHGCKDLCSLSDISDHEASLEVPTALPPLTPGTNRKVNEVLKASFASWEKEVQKCNITKDPREWTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTGDILWEHLDILQKDCEKPNEDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINSRLSMDYVTSAGNSDNKNFHRATPHSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSNTNNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQNLVGHTPEELVAKYDLKIEKKDVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : .*: :. .:. :: * * . ::* *** :: :.:.***:*:.: ** :: .*.*:* *.* :* *: ** ***** .:::. * *.* : ***: ** ::* *.********: : *: : : .. : * : . . . . : . . . : .:: .* . . ::. :. .: :. : : .: .* . :.*: . : .* :: . . . :.*: . :: : .* :: . . * :**************** **:****************:********** ****************************:*************.*:*.***** * .:: : . ", "identical_positions": 147, "similar_positions": 118, "identity": "20.47%" }, { "cls_id": "homologset.agr.FB:FBgn0003124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07832-1", "uniprot_id": "PLK1_MOUSE", "id": "Q07832-1", "name": "Serine/threonine-protein kinase PLK1", "aln": "----------MNAAAKAGKLARAPADLGKGGVPGDAVPGAPVAAPLAKEIPEVLVDPRSRRQ-------------------YVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQHVVGFHDFFEDSDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNQVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYEGERKKTLCGTPNYIAPEVLS--KKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP--KHINPVAASLIQKMLQTDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAP--------------------SSLDPSSRKPLKVLN------KGVENPLPDR----PREKEEPVVRETNEAIECHLSDLLQQLTSVNASKPSERGLVRQEEAED------------------------------------------PACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTE----SYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASR-LRYARTMVDKLLSSRSASNRLKAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62673-1", "uniprot_id": "PLK1_RAT", "id": "Q62673-1", "name": "Serine/threonine-protein kinase PLK1", "aln": "----------MNAAAKAGKLARAPADLGKGGVPGDAAPGAPGAAPLAKEIPEVLMDPRSRRQ-------------------YVRGRFLGKGGFAKCFEISDSDTKEVFPGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQHVVGFHGFFEDSDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNQVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYEGERKKTLCGTPNYIAPEVLS--KKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP--KHINPVAASLIQKMLQTDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAP--------------------SSLDPSNRKPLTVLN------KGVENPLPDR----PREKEEPVVRETNEAIECHLSDLLQQLTSVNASKPSERGLVRQEEAED------------------------------------------PACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTE----SYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFRTYRLSLLEEYGCCKELASR-LRYARTMVDKLLSSRSACNRLKAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53350-1", "uniprot_id": "PLK1_HUMAN", "id": "P53350-1", "name": "Serine/threonine-protein kinase PLK1", "aln": "----------MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRR-------------------YVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLS--KKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP--KHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAP--------------------SSLDPSNRKPLTVLN------KGLENPLPER----PREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAED------------------------------------------PACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTE----SYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASR-LRYARTMVDKLLSSRSASNRLKAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52304-1", "uniprot_id": "POLO_DROME", "id": "P52304-1", "name": "Serine/threonine-protein kinase polo", "aln": "-------------------MAAKPEDK-------------------STDIPDRLVDINQRKT-------------------YKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILT--KKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVP--SYLRKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRIGSND--------------------TIEDSMHRKPLMEMNGIRPDDTRLESTFLKANLH-DAITASAQVCRHSEDYRSDIESLYQQLTNLINGKPRILQGNLGDENTD------------------------------------------PAAQPLFWISKWVDYSDKYGFGYQLCDEGIGVMFNDTTKLILLPNQINVHFIDKDGKE----TYMTTTDYCKSLDKKMKLLSYFKRYMIEHLVKAGANNVNIESDQISRMPHLHSWFRTTCAVVMHLTNGSVQLN-FSDHMKLILCPRMSAITYMDQEKNFRTYRFSTIVENGVSKDLYQK-IRYAQEKLRKMLEKMFT-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32562-1", "uniprot_id": "CDC5_YEAST", "id": "P32562-1", "name": "Cell cycle serine/threonine-protein kinase CDC5/MSD2", "aln": "MSLGPLKAINDKQLNTRSKLVHTPIKGNTADLVGKENHFKQTKRLDPNNDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKD-DSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRG-TFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLESMSSDKIQRQKRDYISSIKSSIDKLEEYHQNRPFLPHSLSPGGTKQKYKEVVDIEAQRRLNDLAREARIRRAQQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLPKSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLSRVSTFGRE---EYHKDDVFLRRYTRYKPFVMFELSDGTFQFN-FKDHHKMAISDGGKLVTYISPSHESTTYPLVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTVD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . ..: . ..:: * * :*:*:****:*::* * :: ::*..* *.* : . : ::* ** **:*: * ::* * . ***.. ::::**:* . *::** **** :** * *:: ** . :*:* .::*********:*::. .:********: : :.*** *:**********:* :.*******:**:* ::*:**:*:***:: :: * :** :: .* . : . :: :*. :* **:: :::: :: . .* :* : :: .*.: * *: :. :*. . . . * . . ::* : : * : ::******:*:*:.***. :.:**:**: * :: : .. :*. *. * :: :. ..* ::: ::.:* .** :* :..: : .*: : * :::.*::*:.*:* *.** *: :. :**:. .:: ** : : : * . :* : : *.. : ", "identical_positions": 154, "similar_positions": 194, "identity": "21.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LT82-1", "uniprot_id": "F1LT82_RAT", "id": "F1LT82-1", "name": "", "aln": "MKFTLGLGSRAWRVSWERAAAAAAAVPGAGG-ALGSGSLRVSS----RRGPRLARALPLCLS-GGGGARALPDCAGPSPRRS---GARQLAGPRAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLA-QPGPYEASKQ--PPPQPALPYNHIYQYPYPSPVSPTGTKMGSHPGVPGSAGHVSIPR---SWPSAHSVSNILGIRTFMEQTGALAGSEGAAYSPKVEDWASVNRAAFSTS---SAVNGLEKPALEADIKYTQSASSLSAVGGFLPACAYPAS------NQHGVYSAPAAGYLSPGPPWPPAQAPPLAPHGAGVAVHGGELAAAMTFKHPSREGTD------------------RKPPSPGGK--------------------ATDALGS--LHGLSIPASTS-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09084-1", "uniprot_id": "PAX1_MOUSE", "id": "P09084-1", "name": "Paired box protein Pax-1", "aln": "MKFTLGLGSRAWRVSWERAAAAAAG-PGAGG-ALGSGSLRVSS----RRGPRLARALPLCLS-GGGGARALPDCAGPSPRRS---GARQLAGPRAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLA-QPGPYEASKQ--PPPQPALPYNHIYQYPYPSPVSPTGTKMGTHPGVPGSAGHVSIPR---SWPSAHSVSNILGIRTFMEQTGALAGSEGAAYSPKMEDWAGVNRAAFPTS---PAVNGLEKPALEADIKYTQSASSLSAVGGFLPACAYPAS------NQHGVYSAPAAGYLSPGPPWPPAQAPPLTPHGAGVAVHGGELAAAMTFKH--REGTD------------------RKPPSPGGK--------------------ATDALGS--LHGLPIPASTS-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15863-1", "uniprot_id": "PAX1_HUMAN", "id": "P15863-1", "name": "Paired box protein Pax-1", "aln": "MKFTLGLGSRAWRVSWEGAAAAAAG-PGAGGSALRCRAQRVSSPRLGRRGSRLSGALPLCLSRGGGGAQALPDCAGPSPGHPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLA-QPGPYEASKQ--PPSQPTLPYNHIYQYPYPSPVSPTGAKMGSHPGVPGTAGHVSIPR---SWPSAHSVSNILGIRTFMEQTGALAGSEGTAYSPKMEDWAGVNRTAFPAT---PAVNGLEKPALEADIKYTQSASTLSAVGGFLPACAYPAS------NQHGVYSAPGGGYLAPGPPWPPAQGPPLAPPGAGVAVHGGELAAAMTFKHPSREGSLPAPAARPRTPSVAYTDCPSRPRPPRGSSPRTRARRERQADPGAQVCAAAPAIGTGRIGGLAEEEASAGPRGARPASPQAQPCLWPDPPHFLYWSGFLGFSELGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T8Y5-1", "uniprot_id": "A0AB32T8Y5_DANRE", "id": "A0AB32T8Y5-1", "name": "", "aln": "-----MLSCLA-------------------------------------------------------------------------------------EQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKNIRDYKQSDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLS-QPNPYENGKQ--APPQSSLSYNHIYPYSYPNAMSPSGTKMSSPPGVPVTGGHVSISR---GWPSAHTVSNILGIRAFMDPT-AIASAEG--YAPKMEDWG-VNRATFQS----HGVNGIDKSSIDADIKYPQPSSTLSS---YVPACAYSPS------NQYGVYSGPAGGYVSPGHHWQ-AQGTSLTHPGGGVAMHPSDIHSSMAFKHAVRDGDR-------------------KPPSPLSKQ-------------------QHEALSG--IHGLSLSTSSS-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2L4T2-1", "uniprot_id": "PAX9_RAT", "id": "Q2L4T2-1", "name": "Paired box protein Pax-9", "aln": "-----------------------------------------------------------------------------------------------MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLA-QQGHYDSYKQHQPAPQPALPYNHIYSY--PSPITAAAAKVPTPPGVPAIPGSVALPR---TWPSSHSVTDILGIRSITDQG---VSDSSPYHSPKVEEWSSLGRNNFSAAA-PHAVNGLEKGALEQEAKYGQAPNGLPAVSSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVA-GHGWQHAGSTPLSP-------HNCDIPTSLAFKG------------------------------------------------------MQAAREG----SHSVAASAL-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47242-1", "uniprot_id": "PAX9_MOUSE", "id": "P47242-1", "name": "Paired box protein Pax-9", "aln": "-----------------------------------------------------------------------------------------------MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLA-QQGHYDSYKQHQPAPQPALPYNHIYSY--PSPITAAAAKVPTPPGVPAIPGSVALPR---TWPSSHSVTDILGIRSITDQG---VSDSSPYHSPKVEEWSSLGRNNFPAAA-PHAVNGLEKGALEQEAKYGQAPNGLPAVSSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVA-GHGWQHAGSTPLSP-------HNCDIPASLAFKG------------------------------------------------------MQAAREG----SHSVTASAL-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55771-1", "uniprot_id": "PAX9_HUMAN", "id": "P55771-1", "name": "Paired box protein Pax-9", "aln": "-----------------------------------------------------------------------------------------------MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLA-QQGHYDSYKQHQPTPQPALPYNHIYSY--PSPITAAAAKVPTPPGVPAIPGSVAMPR---TWPSSHSVTDILGIRSITDQ----VSDSSPYHSPKVEEWSSLGRNNFPAAA-PHAVNGLEKGALEQEAKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVA-GHGWQHAGGTSLSP-------HNCDIPASLAFKG------------------------------------------------------MQAAREG----SHSVTASAL-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23757-1", "uniprot_id": "POXM_DROME", "id": "P23757-1", "name": "Paired box pox-meso protein", "aln": "------------------------------------------------------------------------------------------MDPESQCPQYGEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGAIGGSKPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLGSLGHQHTPGTVMGSGSSSGGGSVSSNGGQNNGTSASNNINLSNLGNPGGGPHHPHHHHHHQSAAAAASAHHVHAHAHAHAHLYNSIYQPYSAAAAYSMKTPCGSPSPPQGAGGQGSVPHPHQLRSVAAAAAAAHWPSSHSVSDILAHHQAVALRAS------CQVGVGVGGMGGMGSTVSPLPMTPSP-VAGTAGGQPLLDCEGGAGQQSPYNYYMYFQ------------------------------------------------NGGMHHHHHHGGMMAAGATGL-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :******************* *:******:**************************:********************.**: ** ** **************::*:*** ***************:*.*. * . .. ::. * . . . ::: . * * : .*:* * :: . :: * . : : . : : .. :. . * : . . . .* : : .. :: : :. . . .: ", "identical_positions": 123, "similar_positions": 62, "identity": "22.36%" }, { "cls_id": "homologset.agr.FB:FBgn0003132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62137-1", "uniprot_id": "PP1A_MOUSE", "id": "P62137-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62136-1", "uniprot_id": "PP1A_HUMAN", "id": "P62136-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62138-1", "uniprot_id": "PP1A_RAT", "id": "P62138-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05547-1", "uniprot_id": "PP13_DROME", "id": "Q05547-1", "name": "Serine/threonine-protein phosphatase alpha-3 isoform", "aln": "--MAEVLNLESIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREILLAQPILLELEAPLKICGDIHGQYYDLLRLFEYGGYPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTIGWGENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDNTLMCSFQILKPVEKRKK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P63088-1", "uniprot_id": "PP1G_RAT", "id": "P63088-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRGMITKQAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32598-1", "uniprot_id": "PP12_YEAST", "id": "P32598-1", "name": "Serine/threonine-protein phosphatase PP1-2", "aln": "-MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSLPR-------------------QAGGRKKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::::.** *****:*::**::*:* *.*** ** *:*.*:: **********:*********************:***:***************************:*.****:************************.***************:.**:****** ******** *******:*****:** ************** **.***********.:** :**:*:*::****************:***************************::*:********.:* ", "identical_positions": 242, "similar_positions": 43, "identity": "72.89%" }, { "cls_id": "homologset.agr.FB:FBgn0003134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62138-1", "uniprot_id": "PP1A_RAT", "id": "P62138-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62137-1", "uniprot_id": "PP1A_MOUSE", "id": "P62137-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62136-1", "uniprot_id": "PP1A_HUMAN", "id": "P62136-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63087-1", "uniprot_id": "PP1G_MOUSE", "id": "P63087-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK---------PNATRPVTPPRGMITKQAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63088-1", "uniprot_id": "PP1G_RAT", "id": "P63088-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK---------PNATRPVTPPRGMITKQAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36873-1", "uniprot_id": "PP1G_HUMAN", "id": "P36873-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK---------PNATRPVTPPRGMITKQAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48461-1", "uniprot_id": "PP11_DROME", "id": "P48461-1", "name": "Serine/threonine-protein phosphatase alpha-1 isoform", "aln": "MSD--IMNIDSIISRLLEVRGARPGKNVQLSESEIRSLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYAENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLSSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFLQKHEFDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRRFVYPN---FGSSGRPLTPPRGANNKNKKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32598-1", "uniprot_id": "PP12_YEAST", "id": "P32598-1", "name": "Serine/threonine-protein phosphatase PP1-2", "aln": "-MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSL------------------PRQAGGRKKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::*.** *****:*::**::*:* *.*** ** *:*.**:.**********:*****************************************************:*.****:************************.***************:***:****** ********.*******:*****:** ************** **.***********.:** :**:*::::****************:***************************::*:*********:* ** : * ", "identical_positions": 251, "similar_positions": 40, "identity": "75.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD40-1", "uniprot_id": "D3ZD40_RAT", "id": "D3ZD40-1", "name": "Papilin", "aln": "MLASAQGCGYSGYPAPMPADSHRFFYCDAALGLQLLEPGCSERLQKLERVGTEMQLLLLLSLLLLLASTPGSWAQNVRRQSDTWGAWGEWSPCSRTCGGGISFRERPCYSQRRDGGASCVGPARSHRTCHTESCPDSVRDFRAEQCAEFDGTDFQGRRYRWLPYYAAPNKCELNCIPKGQNFYFKHRDAVVDGTPCEPGKRDICVEGVCRVVGCDHKLDSTKQEDKCLQCGGDGSSCYPITGTFDANDLSRGYNQIFIIPAGATSIHIEEADASRNFLAVKSIRGEYYLNGHWTIEEAQALPVASTVLQYERGVEGDLAPERLQARGPTSEPLVIELIIQESNPGVHYEYYLPV---NDPGRSFSWSYGSWGDCSAECGGGHQSRLVFCT--IDNEAYPDHMCQHQPRPAHRRSCNTHPCPKTKR---------------------------------------------------------------WKVGPWTPCSVSCGGGFQSRSVYCVSSD------------------------------------------GTGGQEAAEETQCAGLAGKPPTTQACN------------LQRCAVWSVEPWGECSVTCGAGIRKRSVTCRGDEDSLVHPAACSLKD--QPTLTEPCVREACPGFRGQAWHVGSWSLCSKSCGSGIRRRQVVCTIGPPGRCVDLQS---SKPAEVEACNRQPCHLPQEVPSIQDSR----------------------------------------------------------------------THPSDRRMLSGPQVSPVADARDQQWATLERPRAQ-------SNPREGQDSHLSSAGRAPTLQHPP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQPPLRPSSGARDCRHSPHGCCPDGHTPSLGPQWQGCPL---------------------------AGASCLKSRYGCCPDGVSAAKGPQQAGCTRSHSSDNTGNRPGSRAVVSKDPKIHQSQAHPSEI----------------------------------------------------------------------------------------------------------------------------------------SECRSSQFGCCYDNVAFAAGPLGEGCVGQPS-YAYPVR-------------------------------------------------------------------------CLLPSAQGSCGDWAARWYFVGSVGRCNRFWYGGCHGNANNFATEQECMDTCRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHGPRRPEAGAAGHRVHMDGGQRGPGGQQEPDWHRIEATVPRLPSPSGSPWSREQEPGPGQAPHIPAQGKR-------PRVPGLDRDARPPVRPTHSPSYRINLADSEPSLVQAAPGQAVQLFCPGNIPP--EFQAGWQKEGRPISSNR-------------------------------------------------------------------------------------YQLQADGS----------------LIISPLRPEDAGIYSCGSQRSG----------------------------------------------------------------------------------------------------------------HEPQKIQLRVTGGDMAVLSEVQPRHFPETRNPDPGHSPQNRGIGVGAEGHRVLSSSHPRP----------------------ATRLRLDRTQPGVIDASPGQQIQLTC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HAEGFPVPTIEWQRDGQLVSSPRHQVQHDGSLVISRVTVEDGGFYTCVAFNGHDRDQRWVQLRVQRELT----------------------------------------------ITGLPPAMTVPEGDTARLLCVVAGDS-VNIRWSRNGLPIQADGHRVHQSPDGTLLIHNLRPRDEGSYTCSAFRGSQAVSRSTEVKVALPAAPAAQSRDLGK-DCIDQPELANCALILQAQLCGNEYYSSFCCASCSRFQPNAQPGWQQG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPX2-1", "uniprot_id": "PPN_MOUSE", "id": "Q9EPX2-1", "name": "Papilin", "aln": "-----------------------------------------------------MQLFPLL-FSLLLTSTPGSWARNVRRQSDTWGTWGEWSPCSRTCGGGISFRERPCYSQRRDGGTSCVGPARSHRTCHTESCPDGVRDFRAEQCAEFDGTDFQGRRYRWLPYYAAPNKCELNCIPKGQNFYYKHKDAVVDGTPCEPGQRDICVDGVCRVVGCDHKLDSIKQEDKCLQCGGDGSSCYPVTGTFDGNDLSRGYNQIFIIPAGATSIRIEEAAASRNFLAVKSIRGEYYLNGHWTIEAAQALPVASTVLQYERGVEGDLAPERLQARGPTSEPLVIELLSQESNPGVHYEYYLPA---NDPGRGFSWSHGSWGDCSAECGGGHQSRLVFCT--IDNEAYPDHMCQHQPRPTHRRSCNTQPCPKTKR---------------------------------------------------------------WKVGPWTPCSVSCGGGVQSRSVYCISSD------------------------------------------GTGGQEAAEETQCAGLVGKPPTTQACN------------LQHCAVWSVEPWGECSVTCGTGIRKRSVTCRGDEGSPVHAAACLLKD--QPTLTEPCVQEACPVFRGQAWHVGSWSLCSKSCGSGIRRRQVVCTIGPPGRCVDLQS---SKPAEMEACNRQPCHLPQEVPSIQDPR----------------------------------------------------------------------TRSSDPRMLSGPRVSPVSDGREQQWAPLERPRAQ-------SNPREGQDPNLSSAGRAPTLQRPP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQPPLRPSSGPRDCRHSPHGCCPDGHTPSLGPQWQGCPL---------------------------AGASCLQSRYGCCPDGVSAAEGPQQAGCTRSHGSDNTGNRPGSRAVASKNPKIHQPQAHEGEP----------------------------------------------------------------------------------------------------------------------------------------SECRSSRFGCCYDNVASAAGPLGEGCVGQPS-YAYPVR-------------------------------------------------------------------------CLLPSAQGSCGDWAARWYFVASVGRCNRFWYGGCHGNANNFASEQECMNTCRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHGPRRPEAGAAGHRAHVDGGQRGPGGQQEPDWHRAGATIPRLPSPSGSPWRREQEPAPGEPPHIPAYGNRPGGQEIRPRVPGLDREARPAVPPTHSPSYRIRLAGSEPSLVQAAPGQAVQLFCPGNIPS--EFQAGWQKEGRPISSNR-------------------------------------------------------------------------------------YQLQADGS----------------LIISRLRPEDAGIYSCGSHRPG----------------------------------------------------------------------------------------------------------------HEPQEIQLRVTGGDMAVFPEGQPRHFPEPRNPDLGHGPPHRGTGAEAGGHRVLSPSHPRP----------------------ATRLRLDRTQPGVVDASPGQRIRLTC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAEGFPVPTIEWQRDGQLVSSPRHQVQPDGSLVISRVDVEDGGYYSCVAFNGQDRDQRWVQLRVLRELT----------------------------------------------ITGLPPAVTVAEGDTARLLCVVAGES-VNIRWSRNGLPIQADGHRVHQSPDGTLLIHNLRPRDEGSYTCSAFRGSQAVSRSTEVKVALP-APAAQSRDLGK-DCIDQPELANCALILQAQLCGNEYYSSFCCASCSRFQPNAQPVWQQG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95428-1", "uniprot_id": "PPN_HUMAN", "id": "O95428-1", "name": "Papilin", "aln": "-----------------------------------------------------MRLLLLV--PLLLAPAPGSSAPKVRRQSDTWGPWSQWSPCSRTCGGGVSFRERPCYSQRRDGGSSCVGPARSHRSCRTESCPDGARDFRAEQCAEFDGAEFQGRRYRWLPYYSAPNKCELNCIPKGENFYYKHREAVVDGTPCEPGKRDVCVDGSCRVVGCDHELDSSKQEDKCLRCGGDGTTCYPVAGTFDANDLSRGYNQILIVPMGATSILIDEAAASRNFLAVKNVRGEYYLNGHWTIEAARALPAASTILHYERGAEGDLAPERLHARGPTSEPLVIELISQEPNPGVHYEYHLPL---RRPSPGFSWSHGSWSDCSAECGGGHQSRLVFCT--IDHEAYPDHMCQRQPRPADRRSCNLHPCPETKR---------------------------------------------------------------WKAGPWAPCSASCGGGSQSRSVYCISSD------------------------------------------GAGIQEAVEEAECAGLPGKPPAIQACN------------LQRCAAWSPEPWGECSVSCGVGVRKRSVTCRGERGSLLHTAACSLED--RPPLTEPCVHEDCPLLSDQAWHVGTWGLCSKSCSSGTRRRQVICAIGPPSHCGSLQH---SKPVDVEPCNTQPCHLPQEVPSMQDVH----------------------------------------------------------------------TPASNPWMPLGPQESPASDSRGQWWAAQEHPSARGDHRGERGDPRGDQGTHLSALGPAPSLQQPP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQQPLRSGSGPHDCRHSPHGCCPDGHTASLGPQWQGCP-----------------------------GAPCQQSRYGCCPDRVSVAEGPHHAGCTKSYGGDSTGGMPRSRAVASTVHNTHQPQAQQNEP----------------------------------------------------------------------------------------------------------------------------------------SECRGSQFGCCYDNVATAAGPLGEGCVGQPS-HAYPVR-------------------------------------------------------------------------CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQGS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LHGPRRPQPGASGRSTHTDGGGSSPAGEQEPSQHRTGAAVQRKPWPSGGLWRQDQQPGPGEAPHTQAFGEWPWGQELGSRAPGLGGDAGSPAPPFHSSSYRISLAGVEPSLVQAALGQLVRLSCSDDTAP--ESQAAWQKDGQPISSDR-------------------------------------------------------------------------------------HRLQFDGS----------------LIIHPLQAEDAGTYSCGSTRPG----------------------------------------------------------------------------------------------------------------RDSQKIQLRIIGGDMAVLSEAELSRFPQPRDP-----AQDFGQAGAAGPLGAIPSSHPQP----------------------ANRLRLDQNQPRVVDASPGQRIRMTC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAEGFPPPAIEWQRDGQPVSSPRHQLQPDGSLVISRVAVEDGGFYTCVAFNGQDRDQRWVQLRVLGELT----------------------------------------------ISGLPPTVTVPEGDTARLLCVVAGES-VNIRWSRNGLPVQADGHRVHQSPDGTLLIYNLRARDEGSYTCSAYQGSQAVSRSTEVKVVSP-APTAQPRDPGR-DCVDQPELANCDLILQAQLCGNEYYSSFCCASCSRFQPHAQPIWQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P0S4-1", "uniprot_id": "A0A8M9P0S4_DANRE", "id": "A0A8M9P0S4-1", "name": "Papilin", "aln": "------------------------------------------------------MLAVAVCLQLFLASV------FMQGIGDNWGEWSSYGECSRSCGGGVTMRTRRCVTHRTDGGHSCVGPDKSYRSCNIQDCPEGSRDFREEQCSQFDGTDFQGKRYKWLPYYGGENPCELNCIPRGENFYYRQKSSVVDGTPCRPGGKDICVDGLCKRLGCDHMLESPQEEDACLQCGGDGQSCSRLKNSFSMRNLPKGYNQMFIIPVGATTISIKETLPTRNYLAIKNLRGEYYLNGHWVIDLSRAASIAGTVLHYQRGREGEKSPEMITGRGPTTEPLVIELITQEVNEGVDYEYYLPN---GGSTEGYYWSYGSWSACSKECGSGYQSRLVFCT--FEDEAYSDYLCASLPRPLSNRTCNEQQCPQTRRMAYVYEAQL---------------------------------------WRPTETPRVYVQVYSWTAGEWSPCPVTCGGGLQARRVECMSHD------------------------------------------STG-SRLVEDSQCTAYTPRPLSQQNCN------------MQKCAQYSIYSWSQCSVTCGSGKQTRDVVCIGSDGASVEDYACGNQP--KPPREQICEMPMCR--SPIAWHIGDWGLCSKSCGSGLRERQVICSDRQRNLYRAEECQGKPKPPTVESCNAQPCYRPQEVPSMQDPT----------------------------------------------------------------------GHDN---TLHG--FMPYSED-----PLLEIPQNN--------------------------AAHSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HGTALTP-----HCSQTQYGCCPDGRTPASGPQHQGCPQDQ-------------------------GQPSCTWSRYGCCHDGVTVAQGQNMEGCPDAWTHWSS-----------------SSDTVPSAP----------------------------------------------------------------------------------------------------------------------------------------VDCHSSTYGCCYDGVTAASGTHGEGCSNPPSNTQRSLS-------------------------------------------------------------------------CDLPNTVGPCDQWTSRFYFDRSASRCLHFWYGGCHGNSNNFASEEECQKMCLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SELRQRDQAHVLSLQHGRRRFPAHVQLSSSGAHRAQRAHQPASN-----AMQQSNPAASWTAEG----------------------------------VSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRRDGVPVDPTR-------------------------------------------------------------------------------------HEQQLDGS----------------LLVGPITLQDSGWFLCVATRDDK---------------------------------------------------------------------------------------------------------------RDHRYIYLSVSG---------------------------SSQNNAGISEVDSSQSYTSQS----------------------SSRFNIDYSP--LVEARAGQTAKLQCS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLPVSAIHAVTIHWSRAGQPLNSLRHSQHSDGTLVIKQLTADDSGLYTCTVTDAQKFEERQVQLRVLGDLR----------------------------------------------ITKAPIDVDVVQGSTAQLACVVTGEN-VNVGWSRNGVPVRPDGHRVHVSADGTLILNNVQSVDEGTYTCNAYTGTLSVSAAAEIRLAKTPQQDIDGGQFSSSDCVDQPELANCKLIVYARLCSSPYYSSFCCSSCARYATDRLRRTHSR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q868Z9-1", "uniprot_id": "PPN_DROME", "id": "Q868Z9-1", "name": "Papilin", "aln": "------------------------MDLSRRLCSTALVAFIVLASIHDSQSRFPGLRQKRQYGANMYLPESSVTPGGEGNDPDEWTPWSSPSDCSRTCGGGVSYQTRECLRRDDRGEAVCSGGSRRYFSCNTQDCPEEESDFRAQQCSRFDRQQFDGVFYEWVPYTNAPNPCELNCMPKGERFYYRQREKVVDGTRCNDKDLDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITTKDLAPGYNDLLLLPEGATNIRIEETVPSSNYLACRNHSGHYYLNGDWRIDFPRPMFFANSWWNYQRKPMGFAAPDQLTCSGPISESLFIVMLVQEKNISLDYEYSIPESLSHSQQDTHTWTHHQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVEEQACGTEPCAPHWVEGEWSKCSKGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVKNCPKYHLGPWTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVEEKPETEKSCLLTPCEGVDWIISQWSGCNACGQNTETRTAICGNKEGKVYPEEFCEPEVPTLSRPCKSPKCEAQWFSSEWSKCSAPCGKGVKSRIVICGEFDGKTVTPADDDSKCNKETKPESEQDCEGEEKVCPGEWFTGPWGKCSKPCGGGERVREVLCLSNGTKSVNCDEE---KVEPLSEKCNSEACTEDEILPLTSTDKPIEDDEEDCDEDGIELISDGLSDDEKSEDVIDLEGTAKTETTPEAEDLMQSDSPTPYDEFESTGTTFEGSGYDSESTTDSGISTEGSGDDEETSEASTDLSSSTDSGSTSSDSTSSDSSSSISSDATSEAPASSVSDSSDSTDASTETTGVSDDSTDVSSSTEASASESTDVSGASDSTGSTNASDSTPESSTEASSSTDDSTDSSDNSSNVSESSTEASSSSVSDSNDSSDGSTDGVSSTTENSSDSTSDATSDSTASSDSTDSTSDQTTETTPESSTDSTESSTLDASSTTDASSTSESSSESSTDGSSTTSNSASSETTGLSSDGSTTDATTAASDNTDITTDGSTDESTDGSSNASTEGSTEGASEDTTISTESSGSTESTDAIASDGSTTEGSTVEDLSSSTSSDVTSDSTITDSSPSTEVSGSTDSSSSTDGSSTDASSTEASSTDVTESTDSTVSGGTSDTTESGPTEESTTEGSTESTTEGSTDSTQSTDLDSTTSDIWSTSDKDDESESSTPYSFDSEVTKSKPRKCKPKKSTCAKSEYGCCPDGKSTPKGPFDEGCPIAKTCADTKYGCCLDGVSPAKGKNNKGCPKSQCAETLFGCCPDKFTAADGENDEGCPETTTVPPTTTTEETQPETTTEIEGSGQDSTTSEPDTKKSCSFSEFGCCPDAETSAKGPDFEGCGLASPVAKGCAESENGCCPDGQTPASGPNGEGCSGCTRERFGCCPDSQTPAHGPNKEGCCLDTQFGCCPDNILAARGPNNEGCECHYTPYGCCPDNKSAATGYNQEGCACETTQYGCCPDKITAAKGPKHEGCPCETTQFGCCPDGLTFAKGPHHHGCHCTQTEFKCCDDEKTPAKGPNGDGCTCVESKFGCCPDGVTKATDEKFGGCENVQEPPQKACGLPKETGTCNNYSVKYYFDTSYGGCARFWYGGCDGNDNRFESEAECKDTCQDYTGKHVCLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTCAASENLPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQPGVLKDRCALPKQTGDCSEKLAKWHFSESEKRCVPFYYSGCGGNKNNFPTLESCEDHCPRQVAKDICEIPAEVGECANYVTSWYYDTQDQACRQFYYGGCGGNENRFPTEESCLARCDRKPEPTTTTPATRPQPSRQDVCDEEPAPGECSTWVLKWHFDRKIGACRQFYYGNCGGNGNRFETENDCQQRCLSQEPPAPTPPRAPAPTRQPDPAPTVAQCSQPADPGQCDKWALHWNYNETEGRCQSFYYGGCGGNDNRFATEEECSARCSVNIDIRIGADPVEHDTSKCFLAFEPGNCYNNVTRWFYNSAEGLCDEFVYTGCGGNANNYATEEECQNECNDAQTTCALPPVRGRCSDLSRRWYFDERSGECHEFEFTGCRGNRNNFVSQSDCLNFCIGEPVVEPSAPTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGNGNRFETRDQCERQCGEFKGVDVCNEPVTTGPCTDWQTKYYFNTASQACEPFTYGGCDGTGNRFSDLFECQTVCLAGREPRVGSAKEICLLPVATGRCNGPSVHERRWYYDDEAGNCVSFIYAGCSGNQNNFRSFEACTNQCRPEPNKQDNEIGQNPCDTFDAECQELRCPYGVRRVAARSQPECTQCICENPCEGYSCPEGQQCAIDVASSDDRQFAPVCRDIYKPGECPALSANASGCARECYTDADCRGDNKCCSDGCGQLCVHPARPTQPPRTQAPVVSYPGDARAALEPKEAHELDVQTAIGGIAVLRCFATGNPAPNITWSLKNLVINTNKGRYVLTANGDLTIVQVRQTDDGTYVCVASNGLGEPVRREVALQVTEPVSQPAYIYGDKNVTQIVELNRPAVIRCPAGGFPEPHVSWWRNGQMFGLKNNLMARDYSLVFNSIQLSDLGLYTCEVYNQRRPVSLRVTLKAVGPVRPLSPEEEQYMQYVLNPATRPVTQRPSYPYRPTRPAYVPEPTVNVHAVLALEPKNSYTPGSTIVMSCSVQGYPEPNVTWIKDDVPLYNNERVQITYQPHRLVLSDVTSADSGKYTCRASNAYTYANGEANVSIQSVVPVSP--------ECVDNPYFANCKLIVKGRYCSNPYYTQFCCRSCTLAGQVASPPLHPNAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * *.. . ***:****:: : * * : * * * : : :*. :.**: *** :**:.** :*:* *.*:** . * *****:*:*:.**::::. ***** *. *:**:* * :*** * * :** * :***** :* : .:: .:*. ***:::::* ***.* *.*: .: *:** :. *.*****.* *: .:. *.: :*:* * :*: : ** :*.*.* :: ** * .:.*** :* . *:: .:. ** .**.* *** * *. : :* .:* .::*. . *. : * *:** **.* *:* * *. : . * . .. : * : . : *: : * : *.:**..** * :.* * * . : : .. . *. * *. ***.*..* * *:*:* : * ** :.* : :* . . * .: . : . . . * :: :******::.. ** :*** . * : :*** * .:.*.* : **. : : :: . *. : :*** * :: * *. *** .: * **. *.* ::: ::** * . * :******.** *.* :* ** . * . . . . : . : . .: *. . :. . *: : .. : . *:. :. : *. : : .: : : . : * * . . : . .:. : : : * . .: : * * ** .. .: * :**:. : .* * *:* . : : . * *:. : : *.* : * * * *: * ::.:*: : : *:: :: . *.*.*** * . .. ::: : :*:*:* :*** **: .: *.. **:.*** **: : ", "identical_positions": 267, "similar_positions": 299, "identity": "9.1%" }, { "cls_id": "homologset.agr.FB:FBgn0003139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64620-1", "uniprot_id": "PPP6_RAT", "id": "Q64620-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVP-DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK-LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS---ERVIPPRTTTP-YFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQR6-1", "uniprot_id": "PPP6_MOUSE", "id": "Q9CQR6-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVP-DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK-LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS---ERVIPPRTTTP-YFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00743-1", "uniprot_id": "PPP6_HUMAN", "id": "O00743-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVP-DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK-LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS---ERVIPPRTTTP-YFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27884-1", "uniprot_id": "PPP6_DROME", "id": "Q27884-1", "name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "aln": "MG--DVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGGQVP-HTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYGNANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDPEDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGK-LVTVWSAPNYCYRCGNVAAILSFETAEKRQTKIFLAVPDA---ERVIPKQNTTP-YFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20604-1", "uniprot_id": "PP11_YEAST", "id": "P20604-1", "name": "Serine/threonine-protein phosphatase PP1-1", "aln": "MVSRGPDEWLETIKKCQALTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFSAVPDDYIRESTANHNNQRAGYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *:::* : *: *.**::*:**: * ::*:**:*: **.*************:** :****.* .* . ****:**:************ *: **.::* :***:*****:****:****::** .***.:. *:** :***:**:**:** ::*********:* *****.:.* *:*::*.*.**:****:::: * ********** :*:.:* :*.*:**.****** ** *: * * :***************:*::: .. *:* **** * . .. . ***", "identical_positions": 173, "similar_positions": 80, "identity": "55.63%" }, { "cls_id": "homologset.agr.FB:FBgn0003140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P33329-1", "uniprot_id": "PPZ2_YEAST", "id": "P33329-1", "name": "Serine/threonine-protein phosphatase PP-Z2", "aln": "MGNSGSKQHTKHNSKKDDHDGDRKKTLDLPPLTKSDTTHSLKSSRSLRSLRSKRSEAS-----LASNVQAQTQPLS-----RRSSTLGNGNRNHRRSNNAPITPPNNHYLTSHPSSSRRLSSSSRRSSMGNNNNSELPPSMIQMEPKSPILKNSTSMHSTSSFNS------YENALTDDDDDRGDDGGESPSMAKVTRINTSSSADRGSKRTPLRRHNSLQPEKGVTGFSSTSSKLRRRSDNTLPASYPLNAEAGGNGSDYFSNRSNSHASSRKSSFGSTGNTAYSTPLHSPALRKMSSRDNDDSGDNVNGRGTSPIPNLNIDKPSPSASSASKREYLSAYPTLAHRDSSSSLSPRGKGQRSSSSSSSSQRIYVSPPSPTGDFVHGSCADGDNGSRTNTMVEMKRKKPVRPVDIDEIIQRLLDAGYAAKRTKNVCLKNS-----EIIQICHKARELFLAQPALLELSPSVKIVGDVHGQYADLLRLFTKCGFPPMANYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKIWKTFVDTFNTLPLAAIVTGKIFCVHGGLSPVLNSMDEIRHVSRPTDVPDFGLINDLLWSDPTDSSNEWEDNERGVSFCYNKVAINKFLNKFGFDLVCRAHMVVEDGYEFFNDRSLVTVFSAPNYCGEFDNWGAVMTVSEGLLCSFELLDPLDSTALKQVMKKGRQE--RKLANR-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P26570-1", "uniprot_id": "PPZ1_YEAST", "id": "P26570-1", "name": "Serine/threonine-protein phosphatase PP-Z1", "aln": "MGNSSSK-----SSKKDSHSNSSSRNP-RPQVSRTETSHSVKSAKSNKSSRSRRSLPSSSTTNTNSNVPDPSTPSKPNLEVNHQRHSSHTNRYHFPSSSHSHSNSQNELLTTPSSSSTKRPSTSRRSSYNTKAAADLPPSMIQMEPKSPILKTNNSSTHVSKHKSSYSSTYYENALTDDDND--DKDNDISHTKRFSRSSNSRPSSIRSGSVSRRKSDVTHEEPNNGSYSSNN-----------QENYLVQALTR-------SNSHASSLHSRKSSFGSDGNTAYSTPLNSPGLSKLT----DHSGEYFTSNSTSSLNHHSSRDIYPSKHISND----------DDIENSSQLSNIHASMENVNDKNNN--ITDSKKDPNEEFNDIMQSSGNKNAP---------KKFKKPIDIDETIQKLLDAGYAAKRTKNVCLKNN-----EILQICIKAREIFLSQPSLLELSPPVKIVGDVHGQYGDLLRLFTKCGFPPSSNYLFLGDYVDRGKQSLETILLLFCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKIWKTFIDTFNTLPLAAIVAGKIFCVHGGLSPVLNSMDEIRHVVRPTDVPDFGLINDLLWSDPTDSPNEWEDNERGVSYCYNKVAINKFLNKFGFDLVCRAHMVVEDGYEFFNDRSLVTVFSAPNYCGEFDNWGAVMSVSEGLLCSFELLDPLDSAALKQVMKKGRQE--RKLANQQQQMMETSITNDNESQQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P62138-1", "uniprot_id": "PP1A_RAT", "id": "P62138-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSEK----------------------------------LNLDSIIGRLLEVQ-GSRPGKNVQLTEN-----EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11612-1", "uniprot_id": "PPY_DROME", "id": "P11612-1", "name": "Serine/threonine-protein phosphatase PP-Y", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVLTT----------------------------------HEIDCIIKELTSLN-----GSECTLKEE-----LIERLIQQTREVIKWQPMLLELQAPVNICGDIHGQFTDLLRIFKACGFPPKANYLFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINKIYGFYDEIKRRHTVRLWHSFTDCFNWLPVAALVGERIFCCHGGLSPSLRNLQQINHIQRPTDIPDEGIMCDLLWADLNHTTKGWGHNDRGVSFTFDKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVFSAPNYCGMMNNAGGVMSVSTDLICSFVIILPCHKYKMIATDAN------QMPTNEEE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32945-1", "uniprot_id": "PPQ1_YEAST", "id": "P32945-1", "name": "Serine/threonine-protein phosphatase PPQ", "aln": "--------------------------MRRSPSRSNNNFAVPNCSTNSNSSQQQLTTPSDDLNSNEPNDPDDSRSLPTIKKFNNKHSINNYNTLASAGKNNNNKRASNDNLLIPGENAHKQKIYTKDENLKS----------LYLDIDVSVAKALSSSATAP---------------------------KLINTARTSSTTTATTSNNILTSPSYRESNYSSPS---------------------------------------SYSFSSYYSSATSASSSTSSFLKSSGLSSRVK-----------------SPSSSVKAGSFGAPSSP---------------------TSGIPNPKSSKKPIFLRRYSHDTSSNEG----------------------------------LDIDVAIEKLLQVGESREITKTSKKKNFPFHSWEIQLICYHAREIFLNQPTLLRLQAPIKVVGDVHGQFNDLLRILKLSGVPSDTNYLFLGDYVDRGKNSLETILLLLCYKIKYKDNFFMLRGNHESANVTKMYGFYDECKRRLSSKVWKMFVDVFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVARPTDIPESGLVTDLLWSDPDPQVTDWSENDRGVSYTFSKRNVLDFCAKFKFDLILRGHMVVEDGYEFFARKKFVTIFSAPNYCGEFHNWGAVMSVTTGMMCSFELLKPRALKNKKKLYKTKV---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* * .* . . .: * : ::**:: ** **.*...::: **:***: ****:: *.*. :*************:***** **:.**:** ***:******.*.:.::****** *** . ::*: * * ** **:**:: :*** ***:** *..:.:*.:: ****:*: *:: ****:* * .*:****: :. : .* . ::*: *.* ********* :.:**:******** :.* *.:*:* ::*** :: * . ", "identical_positions": 132, "similar_positions": 85, "identity": "17.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003141", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27213-1", "uniprot_id": "PTPS_RAT", "id": "P27213-1", "name": "6-pyruvoyl tetrahydrobiopterin synthase", "aln": "MNAAVGLRR-RARLSRLVSFSASHRLHSPSLSAEENLKVFGKCNNPNGHGHNYKVVVTIHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQRLLPVG-ALYKVKVYETDNNIVVYKGE---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1Z7-1", "uniprot_id": "PTPS_MOUSE", "id": "Q9R1Z7-1", "name": "6-pyruvoyl tetrahydrobiopterin synthase", "aln": "MSAAGDLRR-RARLSRLVSFSASHRLHSPSLSDEENLRVFGKCNNPNGHGHNYKVVVTVHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADAVSTTENVAVYIWESLQKLLPVG-ALYKVKVFETDNNIVVYKGE---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03393-1", "uniprot_id": "PTPS_HUMAN", "id": "Q03393-1", "name": "6-pyruvoyl tetrahydrobiopterin synthase", "aln": "MSTEGGGRRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVLPVG-VLYKVKVYETDNNIVVYKGE---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48611-1", "uniprot_id": "PTPS_DROME", "id": "P48611-1", "name": "6-pyruvoyl tetrahydrobiopterin synthase", "aln": "MSQQP-----VAFLTRRETFSACHRLHSPQLSDAENLEVFGKCNNFHGHGHNYTVEITVRGPIDRRTGMVLNITELKEAIETVIMKRLDHKNLDKDVEYFANTPSTTENLAVYIWDNIRLQLKKPELLYEVKIHETPKNIISYRGPYPLNGIYNPINKRIAHDSCTNISSDSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * ::* :***.***:* ** ***.:****** :******.* :*::* ** ****:*:::**: :* .**: ******* ** ***:. *****:*****:.:: * **:**:.** :**: *:* ", "identical_positions": 75, "similar_positions": 34, "identity": "43.35%" }, { "cls_id": "homologset.agr.FB:FBgn0003145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATQ4-1", "uniprot_id": "A0A8I6ATQ4_RAT", "id": "A0A8I6ATQ4-1", "name": "", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEG--SDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG-------ANQLMAFNHLIPGGFPP---TAMPTLPTYQLSETSYQPTSIPQAV-----SDPSSTVHRPQPLPPSTVHQSTIPS----------NADSS-------SAYCLPSTRHGFSSYTDSF-------------VPPSGPSNP-------MNPAIGNGLSPQVMGL-LTNHGGVPHQPQTDYALSPLTGG---------LEPTTTVSASCSQRL------------EHMKNVDSLPTSQ------------------------PYCPP--TYSTTGYSMDPV-TGYQYGQYGQ--------SKPWTF-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24610-1", "uniprot_id": "PAX3_MOUSE", "id": "P24610-1", "name": "Paired box protein Pax-3", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEG--SDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG-------ANQLMAFNHLIPGGFPP---TAMPTLPTYQLSETSYQPTSIPQAV-----SDPSSTVHRPQPLPPSTVHQSTIPS----------NADSS-------SAYCLPSTRHGFSSYTDSF-------------VPPSGPSNP-------MNPTIGNGLSPQVMGL-LTNHGGVPHQPQTDYALSPLTGG---------LEPTTTVSASCSQRL------------EHMKNVDSLPTSQ------------------------PYCPP--TYSTAGYSMDPV-TGYQYGQYGQ--------SKPWTF-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23760-1", "uniprot_id": "PAX3_HUMAN", "id": "P23760-1", "name": "Paired box protein Pax-3", "aln": "--------------MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPS-----VSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEG--SDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG-------ANQLMAFNHLIPGGFPP---TAMPTLPTYQLSETSYQPTSIPQAV-----SDPSSTVHRPQPLPPSTVHQSTIPS----------NPDSS-------SAYCLPSTRHGFSSYTDSF-------------VPPSGPSNP-------MNPTIGNGLSPQVMGL-LTNHGGVPHQPQTDYALSPLTGG---------LEPTTTVSASCSQRL------------DHMKSLDSLPTSQ------------------------SYCPP--TYSTTGYSMDPV-TGYQYGQYGQ--------SKPWTF-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57418-1", "uniprot_id": "O57418_DANRE", "id": "O57418-1", "name": "", "aln": "--------------MATLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVLRARFGK-KDDDDECDKKD-EDGEKKTKHSIDGILGDKGN--RTDEG--SDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAG-------ANQLAAFNHLLPGGFPP---TGMPTLPTYQLPESTYPSTTLSQ--------DGSSTLHRPQPLPPSSMHQGGLSA----------DSGSA-------YGLSSN--RHTFSSYSETF-------------MSPTASSNH-------MNP-VSNGLSPQVMSI-LSNPSAVPSQPQHDFSISPLHGG---------LEASNPISASCSQRS------------DPIKSVDSLASTQ------------------------SYCPP--TYSATSYSVDPVTAGYQYSQYGQTAVDYL--AKNVSLSTQRRMKLGDHSAVLGLLQVETGQAY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IKH0-1", "uniprot_id": "A0AC58IKH0_DANRE", "id": "A0AC58IKH0-1", "name": "", "aln": "MRLSGMITQNQYLRMSSLPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRSTVPSGEASSVSSISRVLRARFGK-KDDEDDCDKKD-DTGEKKTKHSIDGILGDKG---RMDEV--SDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAG-------ANQLAAFNHLLPGGFPP---TGMPTLPTYQLPESSYPTTTLPQ--------DVSGTVHRPQPLPPSTMHQGGLSS----------DSSSA-------YGLSSN--RHSFSSYTDTF-------------MSQSASSNH-------MNP-VSNGLSPQVMSI-LSNPSAVAPQPQHEFSISPLHSS---------LEASNPISASCSQRS------------EPIKTADSLPSSQ------------------------SYCPP--TYSTTSYSVDPVTAGYQYSQYGQTAVDYL--AKNVSLSTQRRMKLGEHSAVLGLLQVETGQAY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZRA8-1", "uniprot_id": "D3ZRA8_RAT", "id": "D3ZRA8-1", "name": "", "aln": "--------------MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSG---LVSSISRVLRIKFGK-KEDDEEGDKKE-EDGEKKAKHSIDGILGDKGN--RLDEG--SDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAG-------ANQLAAFNHLLPGGFPP---TGMPTLPPYQLPDSAYPTTTVSQ--------DGGSTVHRPQPLPPSTMHQGGLAA----------AAAAA-------DSSSAYGARHSFSSYSDSF-------------MNPGAPSNH-------MNP-VSNGLSPQVMSI-LSNPSAVPPQPQADFSISPLHGG---------LDSASSISASCSQRA------------DSIKPGDSLPTSQ------------------------SYCPP--TYSTTGYSVDPV-AGYQYSQYGQTAVDYL--AKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47239-1", "uniprot_id": "PAX7_MOUSE", "id": "P47239-1", "name": "Paired box protein Pax-7", "aln": "--------------MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPS-----VSSISRVLRIKFGK-KEDDEEGDKKE-EDGEKKAKHSIDGILGDKGN--RLDEG--SDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAG-------ANQLAAFNHLLPGGFPP---TGMPTLPPYQLPDSTYPTTTISQ--------DGGSTVHRPQPLPPSTMHQGGLAA----------AAAAA-------DTSSAYGARHSFSSYSDSF-------------MNPGAPSNH-------MNP-VSNGLSPQVMSI-LSNPSAVPPQPQADFSISPLHGG---------LDSASSISASCSQRA------------DSIKPGDSLPTSQ------------------------SYCPP--TYSTTGYSVDPV-AGYQYSQYGQTAVDYL--AKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23759-3", "uniprot_id": "PAX7_HUMAN", "id": "P23759-3", "name": "Paired box protein Pax-7", "aln": "--------------MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSG---LVSSISRVLRIKFGK-KEEEDEADKKE-DDGEKKAKHSIDGILGDKGN--RLDEG--SDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAG-------ANQLAAFNHLLPGGFPP---TGMPTLPPYQLPDSTYPTTTISQ--------DGGSTVHRPQPLPPSTMHQGGLAA----------AAAAA-------DTSSAYGARHSFSSYSDSF-------------MNPAAPSNH-------MNP-VSNGLSPQVMSI-LGNPSAVPPQPQADFSISPLHGG---------LDSATSISASCSQRA------------DSIKPGDSLPTSQ------------------------AYCPP--TYSTTGYSVDPV-AGYQYGQYGQTAVDYL--AKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06601-1", "uniprot_id": "PRD_DROME", "id": "P06601-1", "name": "Segmentation protein paired", "aln": "---------------MTVTAFAAAMHRPFFN------GYSTMQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPR-IATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPS-----VSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYGGWSSMQALRPNAPLSPEDSLNSTSSTSQALDVTAHQMFHPYQHTPQYASYPAPGHAHSHHGHPHAPHPHAHPHPQYAGAHPHYPPPSSSAHFMPQNFNAAAFPSPSKVNYTTMPPQPFYPSWY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. .. * ** . *:. . ********************:** ****** .********************** ***********.******: ::**::*::******..*********::*:::. ***.*.** **:***::* : . .:: . . . . * :. . ..: . : : .: ** :***.:.*******.****:*.**:***:*****:*************::*****:********** *** .. :..*: ... * :.:*::.. : : .::: * . . :: . *:..*.: . .: . :: . .*** : : ..* * *.**. * . : . ... .: . ::: .. ::. ::** ** :. *** ::. .* .* ::* .:. * .: : **. :. : ", "identical_positions": 189, "similar_positions": 150, "identity": "29.53%" }, { "cls_id": "homologset.agr.FB:FBgn0003149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04462-1", "uniprot_id": "MYH8_RAT", "id": "P04462-1", "name": "Myosin-8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAALQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNASLINAKKKLENDVSQLQSEVEEVIQRARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6N6-1", "uniprot_id": "MYH16_HUMAN", "id": "Q9H6N6-1", "name": "Putative uncharacterized protein MYH16", "aln": "MGLKVIQQNVHKFLQLRFWGWWKLYNKVKPLLNVARQEEEMKAKEEELRKAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERLTWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTEKEKQALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAIRTRLQAENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKADIDRRIHEKEEEFEATRKNHQRAIESLQA-SLEAEAKGRAEALRLKKKMETDLNEMEIQLDHANKNNSELVKTLKRLQQQIKDLQVQMDEDARQHEELRKQYNLQERRLSLLQTELEEVRSALEGSERSRKLLEQEVVEITEWHNEINIQNQSLLVVKRKLESDVQRISNEHEELISEFRLTEERAKKAMMDAARMAEELRQEQDHCMHLEKIKKNYEVTIKDLQAKMEEAEQLALKGGKRTIMKLEARIKELETELDGEQKQHVETVKTLCKNERRLKELVFQTEEDHKTNQRMQALVEKLQNKLKVYKRQIEEAEDQANQTLARYRKTVHELDDAEDRAGMAETALNKLRTRHRVAGKGITSV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35415-1", "uniprot_id": "MYSP1_DROME", "id": "P35415-1", "name": "Paramyosin, long form", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSSSQAVRSSKYSYRATSTG----------------PGTADVNIEYIQDLS-----------SLSRLEDKIRLLQDDLEVERELRQRIERE------------------------------KADLSVQVIQMS-------------------------ERLEEAEGGAEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTFVTTSTVPGSQVYIQETTRTITE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *:**:*: *: ::*::: * : : :. : : * **: * ***.::. : .: **: .. * ::*: :*. : :.*::::**: :** :**. * :*:*. :::*.* *: *.*: * *****:::** *:: *::::.*::* * *:** :**: * ***:*. :* ::* *:: *:** .* * :: . :: *: :**: **:**. **: :* :*.: * . : ", "identical_positions": 78, "similar_positions": 95, "identity": "7.01%" }, { "cls_id": "homologset.agr.FB:FBgn0003162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05915-1", "uniprot_id": "GCH1_MOUSE", "id": "Q05915-1", "name": "GTP cyclohydrolase 1", "aln": "------------------MEKP---------RG----------VRCTNGFSERE------------------LPRPGASPPAEKSRP----------PEAKGAQPADAWKAGRHRSE--------EENQVN---------LPKLAAAYSSILLSLGEDPQRQGLLKTPWRAATAMQYFTKGYQETIS-DVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGRVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22288-1", "uniprot_id": "GCH1_RAT", "id": "P22288-1", "name": "GTP cyclohydrolase 1", "aln": "------------------MEKP---------RG----------VRCTNGFPERE------------------LPRPGASRPAEKSRP----------PEAKGAQPADAWKAGRPRSE--------EDNELN---------LPNLAAAYSSILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETIS-DVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGRVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALQPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30793-1", "uniprot_id": "GCH1_HUMAN", "id": "P30793-1", "name": "GTP cyclohydrolase 1", "aln": "---------MEKGPVRAPAEKP---------RG----------ARCSNGFPERD------------------PPRPGPSRPAEKPPR----------PEAKSAQPADGWKGERPRSE--------EDNELN---------LPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETIS-DVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48596-1", "uniprot_id": "GCH1_DROME", "id": "P48596-1", "name": "GTP cyclohydrolase 1", "aln": "MSFTRQLSEMSASELNDAIDDTNFPQAHILSRGRNNSVCSTSSTSGTSSLADRQQNQAEEATAIAGTPVEEVAPAPALVPLAGNQRPRLILKTNGSSPDSDGTQPKTPLTPRTSTTPGHEKCTFHHDLELDHKPPTREALLPDMARSYRLLLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQSLE-DVLNGAVFDEDHDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPCNKILGLSKLARIVEIFSRRLQVQERLTKQIAVAVTQAVQPAGVAVVVEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEFLNLVNSK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51601-1", "uniprot_id": "GCH1_YEAST", "id": "P51601-1", "name": "GTP cyclohydrolase 1", "aln": "---------MHNIQLVQEIERH------------------------ETPLNIRP------------------TSPYTLNPPVERDGF---------------SWPSVGTRQRAEETE-------EEEKER----------IQRISGAIKTILTELGEDVNREGLLDTPQRYAKAMLYFTKGYQTNIMDDVIKNAVFEEDHDEMVIVRDIEIYSLCEHHLVPFFGKVHIGYIPNKKVIGLSKLARLAEMYARRLQVQERLTKQIAMALSDILKPLGVAVVMEASHMCMVSRGIQKTGSSTVTSCMLGGFR-AHKTREEFLTLLGRRSI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * . . . : * : .: : : :: : :* ***: :*:**:.** * *.** :*****: .: **::.*:*:*******:*:**:::*:******** *:* ***:* ::::*******:.*:::**************:*::: ::* **.**:*. ***** **:** .*.**** *** ** *******.*: ", "identical_positions": 105, "similar_positions": 62, "identity": "32.11%" }, { "cls_id": "homologset.agr.FB:FBgn0003165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8L5-1", "uniprot_id": "D3Z8L5_RAT", "id": "D3Z8L5-1", "name": "Pumilio homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVAC-VLKRKAVLWQDSFSPH---LKHH-PQEPANPNMPVVLTSGTGSQAQPQPAAN----QALAAGTHSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNTSKHRWPTGDNIHAEHQVRSMD-ELN------------------------------------------HDFQALALEGRAMGEQLLPGKKFWETDE-----SSKDGP-------KGIFLG-DQWRDSAWGTS--DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDKG--EKKNKG-AFDGDKLGDLKEEGDVMD-KTNGLPVQNGIDADVKDFSRTPGNCQSS-ANEVDLLGPN------------QNGSEGLAQ-------LTSTNGAKP-VEDFSNMESQSVPLDPMEHVG-----MEPLQFDYSGTQVPVDSAA-----ATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIG------LAPAAFVPNPYIISAAPPGTDPYTAG-LAAAATLG-PAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSATQQSAPQAQQGQQQVLRGGASQRPLTPNQNQQ--GQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQ-PQPQQQ---PSNNLA-SSSFYGNNSLSSNSQ----SSSLFSQGSAQPA-NTSLGFGSSS-SLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSS-SLAPIGHSFYNSLSFSSSPGPVGMPLPSQGPGHS-QTPPPSL-SSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATAAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSHEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTM------NDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPICGPPNGII--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U78-1", "uniprot_id": "PUM1_MOUSE", "id": "Q80U78-1", "name": "Pumilio homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVAC-VLKRKAVLWQDSFSPH---LKHH-PQEPANPNMPVVLTSGTGSQAQPQPAAN----QALAAGTHSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNTSKHRWPTGDNIHAEHQVRSMD-ELN------------------------------------------HDFQALALEGRAMGEQLLPGKKFWETDE-----SSKDGP-------KGIFLG-DQWRDSAWGTS--DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDKG--EKKNKG-TFDGDKLGDLKEEGDVMD-KTNGLPVQNGIDADVKDFSRTPGNCQNS-ANEVDLLGPN------------QNGSEGLAQ-------LTSTNGAKP-VEDFSNMESQSVPLDPMEHVG-----MEPLQFDYSGTQVPVDSAA-----ATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIAG-----LAPAAFVPNPYIISAAPPGTDPYTAG-LAAAATLG-PAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSATQQSAPQAQQGQQQVLRGGASQRPLTPNQNQQ--GQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQ-PQPQQQ---PSNNLA-SSSFYGNNSLSSNSQ----SSSLFSQGSAQPA-NTSLGFGSSS-SLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSS-SLAPIGHSFYSSLSYSSSPGPVGMPLPSQGPGHS-QTPPPSL-SSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATAAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSHEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTM------NDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPICGPPNGII--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14671-1", "uniprot_id": "PUM1_HUMAN", "id": "Q14671-1", "name": "Pumilio homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVAC-VLKRKAVLWQDSFSPH---LKHH-PQEPANPNMPVVLTSGTGSQAQPQPAAN----QALAAGTHSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEHQVRSMD-ELN------------------------------------------HDFQALALEGRAMGEQLLPGKKFWETDE-----SSKDGP-------KGIFLG-DQWRDSAWGTS--DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDKG--EKKNKG-TFDGDKLGDLKEEGDVMD-KTNGLPVQNGIDADVKDFSRTPGNCQNS-ANEVDLLGPN------------QNGSEGLAQ-------LTSTNGAKP-VEDFSNMESQSVPLDPMEHVG-----MEPLQFDYSGTQVPVDSAA-----ATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIG------LAPAAFVPNPYIISAAPPGTDPYTAG-LAAAATLG-PAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQ--GQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQ-PQPQQQ---PNNNLA-SSSFYGNNSLNSNSQ----SSSLFSQGSAQPA-NTSLGFGSSS-SLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSS-SLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHS-QTPPPSL-SSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQ--NEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTM------NDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRK-YTYGKHILAKLEKYYMKNG-------------------------------------------------------------------------------------VDLGPICGPPNGII--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80U58-1", "uniprot_id": "PUM2_MOUSE", "id": "Q80U58-1", "name": "Pumilio homolog 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN------------------------------------------HDFQALALESRGMG-ELLPTKKFWEPDD-----STKDGQ-------KGIFLGDDEWRETAWGTS--HHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKG--DQKGKASPFEEDQNRDLKQ-DDEDS-KINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPS------------TNPPEGLGP-------LPNPTANKPLVEEFSNPETQN--LDAMDQVG-----LDSLQFDYPGNQVPMDSSG-----ATVGLFDYNSQQQLFQRTSALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQAAAAAS--NTANQQAASQAQPGQQQVLRPGAGQRPITPSQGQQ--GQQAESLAAA--ANPTLAFGQSLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSTAAQAAAAAAAAGG--TANSLTGSTNGLFRPIGTQPPQ-QQQQQQQ--PSTNLQ-SNSFYGSSSLTNSSQ----SSSLFSHGPGQPG-SASLGFGSGS-SLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS-SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHS-LTPPPSL-SSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQIVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQ------NDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRK-YTYGKHILAKLEKYYLKNS-------------------------------------------------------------------------------------PDLGPIGGPPNGML--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8F9-1", "uniprot_id": "A0A0G2K8F9_RAT", "id": "A0A0G2K8F9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN------------------------------------------HDFQALALESRGMG-ELLPTKKFWEPDD-----STKDGQ-------KGIFLGDDEWRETAWGTS--HHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKG--DQKGKASPFEEDQNRDLKQ-DDEDS-KINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPS------------TNPPEGLGP-------LPNPTANKPLVEEFSNPETQN--LDAMDQVG-----LDSLQFDYPGNQVPMDSSG-----ATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQAAAAAS--NTANQQAASQAQPGQQQVLRPGAGQRPITPSQGQQ--GQQAESLAAAAAANPTLAFGQSLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAAGG--TANSLTGSTNGLFRPIGTQPPQ-QQQQQQ---PSTNLQ-SNSFYGSSSLTNSSQ----SSSLFSHGPGQPG-SASLGFGSGS-SLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS-SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHS-LTPPPSL-SSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEIVQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALANRIRGHVLPLALQMYGCRVIQKALESISSDQQ--SEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQ------NDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRK-YTYGKHILAKLEKYYLKNS-------------------------------------------------------------------------------------PDLGPIGGPPNGML--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TB72-1", "uniprot_id": "PUM2_HUMAN", "id": "Q8TB72-1", "name": "Pumilio homolog 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN------------------------------------------HDFQALALESRGMG-ELLPTKKFWEPDD-----STKDGQ-------KGIFLGDDEWRETAWGAS--HHSMSQPIMVQRRSGQGFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGNFGTRDAETDGPEKG--DQKGKASPFEEDQNRDLKQGDDDDS-KINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPN------------TNPSEGLGP-------LPNPTANKPLVEEFSNPETQN--LDAMEQVG-----LESLQFDYPGNQVPMDSSG-----ATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQAAAAAN--NTASQQAASQAQPGQQQVLRAGAGQRPLTPNQGQQ--GQQAESLAAAAAANPTLAFGQGLATGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGG---TASSLTGSTNGLFRPIGTQPPQ-QQQQQP----STNLQ-SNSFYGSSSLTNSSQ----SSSLFSHGPGQPG-STSLGFGSGN-SLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS-SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHS-LTPPPSL-SSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQL------------------------VQDQYGNYVIQHVLEHGRPED------KSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQ------NDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRK-YTYGKHILAKLEKYYLKNS-------------------------------------------------------------------------------------PDLGPIGGPPNGML--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NFM3-1", "uniprot_id": "A0A8M1NFM3_DANRE", "id": "A0A8M1NFM3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIPCSILGMNDVPWQETQCGT---LHTNGAPETGGVRVHAGCPLATVGGARQVPGGV----HPLQGMANPNPCTQPL-LSGRSQDDATVGYFFQRQPGEQMGG-------CTGNKHRWPTGDGNHVD-QLRSVD-EMN------------------------------------------YNFQALALESRGMG-ELLPAKKLWESDE-----LAKDGR-------KAMLVG-EEWRENAWSSS--HHALSQPIMVQKRPGQGYNGTGETSSVLSPRSEGGGLGVSMVEYVLSSSPGDKMDGRYRNGGYGEADADPDGREKG--ESKEKSSPFEENKSPEMKVGDEGDTSKANARGLLNGMDRDCKDFNPTPGSRQASPTEAVERLGPS------------QAGLEIMVQHHQHTLQAPNPVTNKPPPEDFQSQEAQN--MGGMEQQAG----LEALQFDYGGNQIQLDSSG-----AAVGLFNYDSQQQLFQRSSHLTVQQLNAAQQQQYALAAAQQQHLG-------LAPAFVPNPYIINAAPPGADPYTAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQATAAAS--HSANQQASSQG-PGQQ-VIRAGSNQRPLTPGQSQQ--SQQES--LAAAATNPTLAF-----PGMSGYQVLAPAAYYDQTGALVMGPGTRTGLGGPVRLVQ-TPLLINPAAAQAAAAASVSGS---GNSMSGPANGLYRSMACQQPQQPQPQQQLPPPSSGLP-SNSFYGSGSVAPSSQ----SSSLFSHTSAAPPPSTSLGFSSTSGSLGVGLGSALGAFGSSVSSSTNSSAVRRDSLLASSELYKRGGGGSLTPIGQSFYNSLGYSSSPSPIGL-----TPGHSPLTPPPSLPSSHGSSSSIHLGGLPNGSGRYISAAPGAEAKYRSSGSTSSLFSSSSQLFPPPRARYSRSDVMPSGRSRLLEDFRNNRFPNLQLRDLPGHMVEFSQDQHGSRFIQQKLERATSAERQMVFGEILQAAYQLMTDVFGNYVIQKFFEFGSADQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISDIVRELDGHVLKCVKDQNGNHVVQKCIECVQPQALQFIIDAFQGQVFVLSTHPYGCRVIQRILEHCTQEQTLPILEELHQHSEQLGQKYQGVSLEMTPKTYYTVSSDALFKDQYGNYVIQHVLEHGRPED------KSKIVAEVRGKVLALSQHKFASNVVEKCVIHSSRAERALLIDEVCCQ------KDGPHSALYTMMKDQYANYVVQRMIDMAEPAQRKIIMHKIRPHIATLRK-YTYGKHILAKLEKYYMKSG-------------------------------------------------------------------------------------SDLGPIGGPTNGLM--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25822-1", "uniprot_id": "PUM_DROME", "id": "P25822-1", "name": "Maternal protein pumilio", "aln": "MKFLGGNDDRNGRGGVGVGTDAIVGSRGGVSQDAADAAGAAAAAAVGYVFQQRPSPGGVGVGVGGVGGGVPGVGAVGSTLHEAAAAEYAAHFAQKQQQTRWACGDDGHGIDNPDKWKYNPPMNPANAAPGGPPGNGSNGGPGAIGTIGMGSGLGGGGGGGAGGGNNGGSGTNGGLHHQSMAAAAANMAAMQQAAALAKHNHMISQAAAAVAAQQQHQHPHQQHPQQQQQQQQAQNQGHPHHLMGGGNGLGNGNGLGIQHPGQQQQQQQQQQQQQHPGQYNANLLNHAAALGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQTTVPMGAAMMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVPPPSRAYAHGGASDTSNSGNAGILSPRDST---CAKVVEYVFSGSPTNK-DSSLSGLEPHLRNLKFDDNDKSRDDKEKANSPFDTN---GLKKDDQVTN----SNGVVNGIDDD-KGFNRTPGSRQPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGG------GLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMNGVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQ-QNFDVQQLFRSQNPGLAAVATNAAAAA--------AAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAA--YAAQQATSYVINPGQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPS-QQGAENQPYQVIPAFLDHTGSLLMG-GPRT--GTPMRLVSPAPVLVPPGATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVAAAANAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGAPITPPPSAQSCLLGS---RAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNM---FGSNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAG----GVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQ--QEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQL------------------------IQDQYGNYVIQHVLEHGKQED------KSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTF------NDN---ALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRK-YTYGKHINAKLEKYYMKITNPITVGTGAGGVPAASSAAAVSSGATSASVTACTSGSSTTTTSTTNSLASPTICSVQENGSAMVVEPSSPDASESSSSVVSGAVNSSLGPIGPPTNGNVVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07807-1", "uniprot_id": "PUF3_YEAST", "id": "Q07807-1", "name": "mRNA-binding protein PUF3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMNMDMDMDMELASIVSSLSALSHSNN--------NGG-----------------QAAAAGIVNGGAAGSQQIGGFRRSSFTTANEVDSEILLLHGSSESSPIFKKTALSVGTAP-----------------------------------PFSTNSKKFFGNGGNYYQYRSTDTASLSSASYNNYHTHHTAAN-------------------------------------------LGKNNKVNHLLGQYSASIAGPVYYNGNDNNN-------------SGGEGFFEKFG----------------KSLIDGTRELESQDRPDAVNTQSQFISKSVSNAS---------------------------------LDTQNTFEQNVESDKNFNKLNRNTTNSGSLYHSSSNSGSS---ASLESENAHYPKRNIWNVANTPVFRPSNNPAAVG----ATNVALPNQQDGPANNNFPPYMNGFPPNQFHQGPHYQNFP---------NYLIGSPSNFISQMISVQIPANEDTE-----------------DSNGKKKKKANRPSS-----------------------------------------VSSPSSPPNNSPFPFAYPN----------PMMFMPPPPLSAPQQQQQQQQQQQQEDQQQQQQQ------ENPYIYYPTPNPIPVKMPKDEKTFKKRNNKNHPANNSNNANKQANPYLENSIPTKNTSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQQQTYHRSPLLEQLRNSSSDKNSNS---NMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALEYIDSNQR--IELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYL------------------------IQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKSNSLGNRHLASVEKLAALVEN------------------------------------------------------------------------------------AEV-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . : . .: * : : . . : . :* .. . . .. :* .*. : : .: .. . : *... . :: * . . .*:: : *: : : : . * : : . * .. : :: : : . . . * . : : . . * * .:: : . : * : . . . :. . . : . . . . . : .. . . .. . :. . *:. : . : : . : . *. :. *. *:.*::: .* :**.:********* :* :..:*::::*.** * .* ***************: ** :* :.:*:: *:****.********* * .:*: ::* **.. **: :********:**.** : * **:.:: *::: ****.********:**. :: .**:**::. * .:*********:**::.: : *. :: : .:*: *:**********.: :.:: :: :*.:: : .: *:***:****:*::::::* * :: **.:: *.* : *:: *.:** .: ", "identical_positions": 157, "similar_positions": 224, "identity": "9.7%" }, { "cls_id": "homologset.agr.FB:FBgn0003169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38445-1", "uniprot_id": "AVR2B_RAT", "id": "P38445-1", "name": "Activin receptor type-2B", "aln": "-------MTAPWAALALLWGSLCAGSGRGEAETRECIYYNAN-WELERTNQSGLERCEGEQDKRLHCYASWRN--SSGTIELVKKGCWLDDFNCYDRQECVATEENPQ--VYFCCCEGNFCN--ERFTHLPEPGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPP-YGHVDIHE------------------------DPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGCSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNSSTSDCLVSLVTSVTNVDLLPKESSI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27040-1", "uniprot_id": "AVR2B_MOUSE", "id": "P27040-1", "name": "Activin receptor type-2B", "aln": "-------MTAPWAALALLWGSLCAGSGRGEAETRECIYYNAN-WELERTNQSGLERCEGEQDKRLHCYASWRN--SSGTIELVKKGCWLDDFNCYDRQECVATEENPQ--VYFCCCEGNFCN--ERFTHLPEPGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPP-YGHVDIHEVRQCQRWAGRRDGCADSFKPLPFQDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRG-SNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLLPKESSI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13705-1", "uniprot_id": "AVR2B_HUMAN", "id": "Q13705-1", "name": "Activin receptor type-2B", "aln": "-------MTAPWVALALLWGSLCAGSGRGEAETRECIYYNAN-WELERTNQSGLERCEGEQDKRLHCYASWRN--SSGTIELVKKGCWLDDFNCYDRQECVATEENPQ--VYFCCCEGNFCN--ERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPP-YGHVDIHE------------------------DPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRG-SNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38444-1", "uniprot_id": "AVR2A_RAT", "id": "P38444-1", "name": "Activin receptor type-2A", "aln": "------MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNAN-WERDRTNQTGVEPCYGDKDKRRHCFATWKN--ISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPE--VYFCCCEGNMCN--EKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHMMA-YPPVLVPT-----------------------QDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRG-TSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSGGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCLGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27038-1", "uniprot_id": "AVR2A_MOUSE", "id": "P27038-1", "name": "Activin receptor type-2A", "aln": "------MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNAN-WERDRTNQTGVEPCYGDKDKRRHCFATWKN--ISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPE--VYFCCCEGNMCN--EKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMA-YPPVLVPT-----------------------QDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRG-TSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27037-1", "uniprot_id": "AVR2A_HUMAN", "id": "P27037-1", "name": "Activin receptor type-2A", "aln": "------MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNAN-WEKDRTNQTGVEPCYGDKDKRRHCFATWKN--ISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPE--VYFCCCEGNMCN--EKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMA-YPPVLVPT-----------------------QDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRG-TSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QG01-1", "uniprot_id": "F1QG01_DANRE", "id": "F1QG01-1", "name": "Serine/threonine-protein kinase receptor", "aln": "------MGPATKLAFGVFLISCSSGAILGRSETQECVFYNYNPSLENRGNRSGIEPCVGDKDKRLHCFATWRN--VSGTVEIVKQGCWLDDVNCYDSTECVEKKEDPD--VFFCCCEGNMCN--EKFFYNPNTAPVQTTSNPLTQKPPLFSTLLYSIVPIMGIAAIVLLSFWMYRHHKLA-YPPVLVPT-----------------------QDPGPMPPSPTLVQKPLQLLEIKARGRFGCVWKAQLLNDYVAVKIFPIQDKLSWQNEYDIYNIPGMRHENILQFIGAEKRG-SNLDIELWLITAYHEKSSLTDYLKANVVTWNELCHIAQTMARGLAYLHSDFPGHR-DGHKPAIAHRDFKSKNVLLKTNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAVGLVLWELAARCTASDGPVDEYMLPFEEEVGQHPTLEDMQEVVVHKKLRPTLRECWQKHPGLAMLCETIEECWDHEAEARLSAGCVEERVVQMQRQTSVSAPEEIVTVVTMVTNVDYPPKESSL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24468-1", "uniprot_id": "AVR2_DROME", "id": "Q24468-1", "name": "Receptor protein serine/threonine kinase put", "aln": "MSKYDLLYLTAQLTLVCCLIGIHGSILPGSHGIIECEHFDEKMCNTTQQCETRIEHCKMEADKFPSCYVLWSVNETTGILRIKMKGCFTDMHECN-QTECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGSNLIYIYIGTSV-FSVLMVIVGMGLLLYRRRKQAHFNEIPT-------------------------HEAEITNSSPLLSNRPIQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHM---DKPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLEGAINFNRDAFLRIDVYACGLVLWEMVSRCDFA-GPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDHDAEARLSSSCVMERFAQLNKYP------STQLLIKNHTNIDDAKESTNCL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: . .. * ** .:: : : .: :* * : ** *:. * :* :.: :**: * :* :*: . : : :.****:*. ** ::: . : . : . : : : : ** .: :**:: . : : :. .** : :*:**** ** **** **:*:* *: ****** :*:* ** .* :::. * *:* *:*:*:..**: . : ***::::.:.** *:**.: ::* ***::*::*:.**::**.:.* : :* **:*:***:********.:*** :******: *:.**. ************************:********:** ******:.:** : ***.*: **** *:* :*:*:::** ** ** ** : : * *.*: :* *:******:******:.*: **. :.: ::. **:* :.:. ", "identical_positions": 194, "similar_positions": 150, "identity": "35.08%" }, { "cls_id": "homologset.agr.FB:FBgn0003175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AG34-1", "uniprot_id": "A0A8I6AG34_RAT", "id": "A0A8I6AG34-1", "name": "", "aln": "--------MFGLKP-PLYYLPGMSHEPKSPSIG-MLSTATRTTATVNPLTPSPLNGALVPTGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPR------------GSSLSSESSPVSSPATN-------------HSSPASTPKRVP-----------MGPIIVPPGGHSVPSTPPVVTIAPTKTVNG-------------------VWRSESRQDSGSRGGSSGRERLLVEPPLAQEKAAGPAIPSHLLSTPYPFGLS----------PSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLTPHPFPHPAFRMDDSYCLSALRSPFYP------IPTPG---------------------------SLPPLHPSAMHLHLSGVRYPP-ELSHSSLAALHSERISSLSAERLQMDEELRREREREREREREADRER-----------EKEREREQREKERE---------------------KELEREREKERERELERQREQRAREKELLAAKALEPT------------------FLPVAELHGLRGHTTEERPKPSEQLTPTRAEKLKDTGVQAPKPVQHPLHPVPAPHHTVP--SLISSHGIFSLPGSSAAT--ALLIQRTNEEEKWLARQR-----RLRQEKEDRQSQVSEFRQQVLEQHLDLGRPLVPTEAEHRPE------------------------------------------------------------------------------------------------------------STRPGPNRHDQGSREPPQHFG----------------------------------GPPPLISPKPQHHTVPTALWN-----------------------------------------PVSLMDNTLETRRAESHSLHSHPTAFEPSRQAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPP-------PPPPPPREAGGLEPQTFPHG--------------------PGPFLAELEKSTQTILGQQRPSLS-----------QTTP---FGELTGSLKSGSPYCHTTAR--------------GPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDD----------SYDESDEEEVRAHLRCVAEQPPLKLD--------------------------------------------------------------------TSSEKLEFLQLFGLTTQQQKE-------------------------------------ELVAQKRRKRRRMLRERSPSPPAIQCKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKR-----KDKERLVEMLRAMKQRALSAAVADS-----------------------------------------------------------------------------------VATNSSRDS---------------------------------------------------------------------PTISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPPSGEKARLSEAPGGKKN------------LSMLHYLRG----------AAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHES--VLQSTQKALQKHKGSSALLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEDDSEEEAEEAPRHQWQG----------------IEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQN--YSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W244-1", "uniprot_id": "Q9W244_DROME", "id": "Q9W244-1", "name": "", "aln": "MEKAKAYIKNELRGGSQQSEPATTPNPTSPASAPGTPQATRHSYPPVELMPSPGAAAHRSARTPGEQYHFGYQAHPAQHYHSGAKSTGRASAPPDNHHVPMTICFVCGGHGSFEPQPLRIRHNAERPSESYFPFLERHEPPNGVPGVVPGQEYVWACMLCFRSLNEQWDAYERQKKPLLQRIYHMKRVDGKGYIGADVATQSEYAAQVLGLSAEHLTQNGLVEGHGDPYALARHYSPQQPSHHHHSTSRNASPSPNPIAAVGGGGEFYPRNSTPSSNHNRYLSRPQSRDMPVASPTSRPPSEPPAMKSAGYAQQKFKLSPAPPVGYQGQAPYHPAQYQQLQQQTAAYHLLQQQVNAGGGATESAHYKGNPYGALPSPGSGPLGPRAASTLEDDNATVLDLRNSSNSSAPPAPRHVGSTASSVSQPSQPQSEVGILDLSMPDKNSITEVCYVCGDEQRRGSLIELSTVKPRETGRPGPSVPYFPLFNEQHPRPARSRPKDPRGMIQACLPCYEDLMQQWNVHQASHKPESERSYLLRKRSTPAAERTTFVCYTCGTDTPSSQLRLVYCCPNAEREPYYPFIKTMKVYKNASPISPQGMVQVCSTCNEKHSGLAEGGPPPASSSIHSAVGGGSPSAGHSLESNSAMYSTSGAITGNSGAQFGGRNSPSEKSLANSDSMSNVRFRPYETNSNNSNSNTARDLKQIRRSDSRPNSPSSSQGAIENGHGQYPCSICKVLCPSNKMDWLSTSAEHMNSHAMHFPCLKANAVTNNNNNNNNTNNNNNNNNNELNSNRVLACKDCKDYLASQWETMDAERVPLEHRRYNIPSPMLTSSSPNGSRHGAMSINTPPSTPSISSSTPASTSIYCYLCGLHSDLTLARVLYASKEGSRPYFPLLLKHNSLPNAEQLRNNSALVCTFCYHSMLNQWRKYEAQSPSVNPADRKYNWHDYNCHLCGITTYRKRVRALPVNEFPFVKHQKSDDGLLLENGEYAVVCLDCYESLRQQASQHDRFGVPISRRAYNWVPQPPPPEDSPESAVARLPCGERSDRIHINNALRPVPGKKTTSPKQYDKSKEVPPKAGQKRPATSPAPHIPVPHHLQTPPGGGAGGLPGSSVANSPIPSSAGGNALMNHALPNNHIGTPSPQQQHQHQQHQQQQQQQQHQAQQQAQQQAVAAAVQQQLAAGVGLPPGAIGAASASSRGSFAAALRTLAKQADIKEEDVGGDRSVPTSGAGGPPPSSSGPGSLNSVAGRVGSERPGEDRVSSNKKRSPPSPQPPEKIARLSHTPQTASLQPELLARSGFQPYRSDERLMHPAGAFPLEAYSHFAGLQGIPPAFLNPAGLPYTEQLYLEHRYQLFRAAGAHPSHPHAAALYPQMASPYSHLYSMMPGAALGISPAMHDRMKLEEEHRARLAREEEREREIQREKERELREQREKEQREKEQREKEQREREQREKEQREKEARERKLRDEERERERERQQLLTASHHYSNQLYSPLNRNLLGSMIPHLNMSLRGPPGALHGLPGMSHYHAAAANAQRQSPHGAMGLNLGMAGLPGVPPLGGHGPNLQHHLQQAAMGLAHPGAAGLTHPGFSAAALGLGAHPHSLNLSHPHMSPHHPASLAHQLPPHTSSAGGGGLSNSIPVTASSSLSASSPHTSLNLTSSVKLSADQVPTSTPSGGVSGSGMPPTTSSSHIPNMGHYYHHGHLAAMHAAAAAASGMTPTAAHQQQPLSLPSSPKITPPITPSSSANGGRAGGSPHAMRHHIAAAVAAAAQQSAMIDKAATPVTHEPTTLDLTGSNSNSSNQAPSNASSGQPTNHEVNGAESNGASQTESKEHLAIKEDGHKSSPPPVALEKKPATPNAAADKPIHPDSSPENSSRRSASPQSDANNSLPAVSVTAAASGKCKEETPKILDSDTTATTKTDIEEEKQRARLSVSPTPTAPKIMVASPDTVSTSGGVTSTTSGTTPPPVVSSSTSSAGKAPALTSDEVSTSAATSAAEPTR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . *. : :*.**: . . *** : . * *** .* .: :*. . :. ** *:. : :. :. .: : * *. * *..*: . *..* ..* ** : .: ..:. ..* : * * *:* :* :.* * .. * . . * . : . : .:* *:. .:. :..*: . .* : . *.* ..: . :: :.:::*. **:* : :. : . * :. .: :: : . .* .*..* :*:** * .* * : *.* *. *. .: * .*:: .:* ** * . : : * :::: * *.: :: :: .:: *.**. *.:: *... ::. .. * : *. : : ::: *: *: .* ** .. . .* *.. .:*.. . . . ** *. .::* .*: :.. * : *.. .** **.. *:* : : :.. *: ::: : : . .** *:.:: * *: *. .**. * :.* *. * :. :*:::*.* * . * :*..: .::..* . . . : .: * : * . .. *. :::*: *:: * . * ****.:: :* * ..* : .*.. . **:**: * **.* * *.** :.** ::. *.* ::. :*::: .: : ::: :::* . :* : . *.. .. * ** :*:*. :* : *:* : *:* *: . :..* :* ::* : * :.. * * * .** * : . :. ** :.:: *: .. *:* ::*** :. * :** . :. .*:*:.*:* * :* .**: . * .. .:. ..**: .. :. *. *: *.: ... *.::. * ..** .. .* ** : **...:. . :*. : * * .* :: :: . . .: :*:::* .::. :*:*. :*.:. * : . . .:..:* *. . .* * :. :.:*.:. .::*. : : . * : :.. *.. :: . : :*:* ::*:** .:. * . :. .: : : * :: * *::.. . : . * ", "identical_positions": 236, "similar_positions": 464, "identity": "11.83%" }, { "cls_id": "homologset.agr.FB:FBgn0003187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09327-1", "uniprot_id": "VILI_HUMAN", "id": "P09327-1", "name": "Villin-1", "aln": "------------------------------------------MTKLSAQVKGSLNIT---------------------------TPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIH---------------KTASSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLV-IRKGGVASGMKHVETNSY--DVQRLLHVKGKRNVVAGEVE-MSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGG-RTYVGVVDGENELASPKLMEVMNHVLGKR-RELKAAVPDTVVEPAL---KAALKLYHVSDSEGNLVVREVATR-PLTQDLLSHEDCYILDQG-GLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPS-TQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQVKFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQ---------HYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQI---------RVPMGKEPPHLMSIFKG-RMVVYQGGTSR--TNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQ-SCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEENLVITP-RLFECSNKTG---------------------------------------RFLATEIP-DFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKA-ELGNSRDWSQITAEVTSPKVD------------------VFNANSNLSSGPLP---------------------IFPLEQLVNKPVEELPEGVDPSRKEEHLSIEDFTQAFGMTPAAFSALPRWKQQNLKKEKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62468-1", "uniprot_id": "VILI_MOUSE", "id": "Q62468-1", "name": "Villin-1", "aln": "------------------------------------------MTKLNAQVKGSLNIT---------------------------TPGIQIWRIEAMQMVPVPSSTFGSFFDGDCYVVLAIH---------------KTSSTLSYDIHYWIGQDSSQDEQGAAAIYTTQMDDYLKGRAVQHREVQGNESETFRSYFKQGLV-IRKGGVASGMKHVETNSC--DVQRLLHVKGKRNVLAGEVE-MSWKSFNRGDVFLLDLGKLIIQWNGPESNRMERLRGMALAKEIRDQERGG-RTYVGVVDGEKEGDSPQLMAIMNHVLGPR-KELKAAISDSVVEPAA---KAALKLYHVSDSEGKLVVREVATR-PLTQDLLKHEDCYILDQG-GLKIFVWKGKNANAQERSGAMSQALNFIKAKQYPPS-TQVEVQNDGAESPIFQQLFQKWTVPNRTSGLGKTHTVGSVAKVEQVKFDALTMHVQPQVAAQQKMVDDGSGEVQVWRIEDLELVPVESKWLGHFYGGDCYLLLYTYLIGEKQ---------HYLLYIWQGSQASQDEIAASAYQAVLLDQKYNDEPVQI---------RVTMGKEPPHLMSIFKG-RMVVYQGGTSR--KNNLEPVPSTRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKTP-SCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEENQVITP-RLFECSNQTG---------------------------------------RFLATEIF-DFNQDDLEEEDVFLLDVWDQVFFWIGKHANEEEKKAAATTVQEYLKTHPGNRDLETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYDDLKA-ELGNSGDWSQIADEVMSPKVD------------------VFTANTSLSSGPLP---------------------TFPLEQLVNKSVEDLPEGVDPSRKEEHLSTEDFTRALGMTPAAFSALPRWKQQNIKKEKGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QVU3-1", "uniprot_id": "F1QVU3_DANRE", "id": "F1QVU3-1", "name": "Villin-1", "aln": "-----------------------------------------MPQEVKTDVPKVLNKT---------------------------TPGLQIWRVENMELVPCPSKTFGQFFEGDSYVILYTH---------------KTSNNFSYDIHYWLGKSTSQDEMGAAAIYTTQMDDHLGGVAVQHRETQGHESATFQGYFKQGII-YKKGGVASGMKQVETNTY--NIRRLLHVKGNKHVVAGEVE-MSWNSFNKGDVFLLDLGSLIIQWNGPKSNRMERLRGMNLAKDIRDRERGG-RAQVAVVEGDDEQSSEEAMKLMKQSLGERPKNIKEAIPDEIVDEKL---KTAIKLYHISDAQGSLVVQEVAVK-PLTQDLLKTEDCYLLDQG-GIKIFIWKGKKASKAERTESLKMAEAYVKAKGYPVS-TYIETVSEGAESSVFKQLFQKWTDKGQTVGMGTTHNPGKIAKVEQVKFDATSMHARPDIAAQQKMVDDGSGEAEVWRIEDNELAPVDRKWLGHFYGGDCYLILYKYEVSSKF---------HYILYMWQGRHASTAELTACAYQAVILDQKYNGEPVQV---------RVPMGKEPMHLMAIFKG-KMIVYEEGSSR--EGSSQSRPSVRLFHVHGTNEFNTRATEVPPRSSSLNSNDVFVLSTD-KCCYLWYGKGCSGDEREMAKSLADIISKREKQVIAEGQEPADFWVNLGGKSQYASNKRLQDENISITP-RLFECSNQTG---------------------------------------RFIATEIT-NFNQDDLDEDDVMLLDIWDQVYLWIGKGANDTEKREAVVTAQEYLKSHPAGRDLDTPVLVVKQGFEPPTFTGWFHAWDPQKWSEGKSYDQLKA-ELGDATDVIKITVDLTQPSSN------------------QTNSSNSTQGGSMPR----------------PVTQTFPAEKLVNVQTEDLPEGVDPTRKEDYLSDDDFALAMGISRMNFYAMPSWKQLNLKKEKGLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WU06-1", "uniprot_id": "AVIL_RAT", "id": "Q9WU06-1", "name": "Advillin", "aln": "-------------------------------------------MSLSSAFRTVTND-----------------------------PGIITWRIEKMELVLVPLSAHGNFYEGDCYIILSTR---------------RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKRGII-YKKGGVASGMKHVETNTY--DVKRLLHVKGKRNIRATEVE-MSWDSFNQGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGG-RAEIGVIEGDKEAASPELMTVLQNTLGRR-SIIKPAVPDEVTDQQQ---KSTIMLYHVSDTTGQLSVTEVATR-PLVQELLNHDDCYILDQS-GTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSS-TNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKTFSIGKIAKIFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKP---------CYILYIWQGRHASQDELAASAYQAVEVDQQFGGAPVQV---------RVSMGKEPRHFMAIFKG-KLVIYEGGTSR--KGNVEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLWTQ-AEHYLWYGKGSSGDERAMAKELAELLCDGDADTVAEGQEPPEFWDLLGGKAPYANDKRLQQETLDIQV-RLFECSNKTG---------------------------------------RFLVTEVT-DFTQDDLSPGDVMLLDTWDQVFLWIGAEANATEKEGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKN-ELGDATAIVRITTDMKNATLS------------------LNSSESGPK--------------------------YYPVEVLLKSQDQELPEDVDPTKKENYLSERDFVSVFGITRGQFVSLPGWKQLQLKKEAGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88398-1", "uniprot_id": "AVIL_MOUSE", "id": "O88398-1", "name": "Advillin", "aln": "-------------------------------------------MSLSSAFRAVSND-----------------------------PRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTR---------------RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGII-YKKGGVASGMKHVETNTY--DVKRLLHVKGKRNIQATEVE-MSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGG-RAEIGVIEGDKEAASPGLMTVLQDTLGRR-SMIKPAVSDEIMDQQQ---KSSIMLYHVSDTAGQLSVTEVATR-PLVQDLLNHDDCYILDQS-GTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSS-TNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKP---------HYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQV---------RVSMGKEPRHFMAIFKG-KLVIYEGGTSR--KGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQ-AEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQV-RLFECSNKTG---------------------------------------RFLVTEVT-DFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKN-ELGDATAIVRITADMKNATLY------------------LNPSDGEPK--------------------------YYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75366-1", "uniprot_id": "AVIL_HUMAN", "id": "O75366-1", "name": "Advillin", "aln": "-------------------------------------------MPLTSAFRAVDND-----------------------------PGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTR---------------RVASLLSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGII-YKQGGVASGMKHVETNTY--DVKRLLHVKGKRNIRATEVE-MSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGG-RAKIGVIEGDKEAASPELMKVLQDTLGRR-SIIKPTVPDEIIDQKQ---KSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQS-GTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSS-TNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKP---------HHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQV---------RVRMGTEPRHFMAIFKG-KLVIFEGGTSR--KGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQ-AEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRLQQEILDVQS-RLFECSNKTG---------------------------------------QFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKE-ELGDAAAIMRITADMKNATLS------------------LNSNDSEPK--------------------------YYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P642-1", "uniprot_id": "A0A8M9P642_DANRE", "id": "A0A8M9P642-1", "name": "", "aln": "-----------MEIYIGISAKLLCLLTLAAEKGLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVS---------------NNP-AQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLI-YKKGGVASGFTHVETNVY--NIQRLLHVKGTKHVTGREVE-VSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGG-RAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQ---ISNVKLYQVSDASGQLLVQEVAVS-PLTQDLLCSSDCYILDQG-GTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPAS-TKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKP---------QYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQV---------RVVMGKEPRHFMAIFKG-RLIIFEGGTGR--SGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTY-QTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEP-RLFECSNQTG---------------------------------------RFLMTEVA-DFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKS-KLG---DVSQITVSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDG----------SQNRAKPSGMQNSEQLVKMPN-QLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3Z8F1-1", "uniprot_id": "D3Z8F1_RAT", "id": "D3Z8F1-1", "name": "", "aln": "-------------------------------------------MDSNQVLPAINSHR-----------------------------ALQIWITENLKMLPLPEKAHGNFFEECCYVVLHSP---------------KATQGGSRDLHCWIGKEASTEAQEAAVSFMHRLQQDLGDQTVLHRESQGHESDCFHSYFRPGVI-YRKGGRASALKLGESNVY--NVQRLLHIRGRKHVSATEVA-LSWNSFNKGDIFLLDLGKVMIQWNGPKASICEKARALSLTCSLRDRERGG-RAQIRVVDAENKAT--DLMSIMEAVLGRRSGSLCASVPSNSVSQLQ---KANIRLYHVFEKGTDLVVQELATR-PLTQDLLQEDGCYLLDQG-GFKIYMWQGRKSSPEERKAAFSRAVGFIQAKGYPNY-TNVEVVNDGAESTAFQQLFWTWSKE-----LNGKKHPRQSKLMQQVNLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQGSQRQPVDPKHHGQLCSGNCYLVLYKYQKLGRV---------QYILYLWQGHQSTVEDVKALNCNAEELDLLHQGALVQG---------HVTMGREPPHFLAIFQG-QLVVLQGNAGN--KGGRLPISDTRLFHVQGTESHNTRTMEVPARASSLTSSDVFFLITS-HVCYLWFGKGCHGDQREMARTVVTVFPGNNKETVLEGQEPLHFWEALGGRAPYPSNKRLPEEISSIQP-RLFECSSHSG---------------------------------------HLVLTEVV-FFGQEDLDKYDIMLLDTCQEIFLWLGEAAG-EWKKAAVAWGHEYLRTHPAERSLATPIIVVKQGREPATFTGWFVTWDPYKWTSSQSYEEMVEGSLGPGSAISEITAEVHNFQLTARPSDSEAGRPTLLAFKGSQDSPENELELGLRVDGETPSMNHTSSCSSSMINGSLPRERLMHQALEDLPQGVDPARKEVGTRPN-----------------CWKTPRDPAP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YD6-1", "uniprot_id": "VILL_MOUSE", "id": "Q91YD6-1", "name": "Villin-like protein", "aln": "-------------------------------------------MDINQDLPAIDSHR-----------------------------ALQIWITENLKMLPLPERAHGNFFEECCYVVLHVPQS------------PKATQGGSSDLHYWIGKDASAEAREAAVSFVQCLQEDLGDQTVLHRESQGHESDCFHSYFHPGVI-YRKGGRDSALKFAETNMY--NVQRLLHIKGRKHVSATEVA-LSWNSFNKGDIFLLDLGKVMIQWNGPKASISEKARALTLTCNLRDRERGG-RAQIAVVDAENEAT--NLLRIMEAVLGCRSGSLCPSVPSNSVSQLQ---KANVRLYHVCEKGTDLVVQELATR-PLTQDLLQEDGCYLLDQG-GFKIYMWQGRKSSPQEKKAALSRAVGFIQAKGYPNY-TNVEVVNDGAESTAFQQLFWSWSKE-----LDRKKHPEKSKLVQG-NLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQDLQRQPVHPKYYGQLCSGNCYLVLYTYQKLGCV---------QYLLYLWQGHQSTVEDTKALNCSAEELDLMHQGALAQG---------HVTMGSEPPHFLAIFQG-RLVVFQGNAGN--KGERPPVSDTRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLITS-HVCYLWFGKGCHGDQREMARTVVSVFPGNNKETVLEGQEPLYFWEALGGRAPYPSNKRLPEEVWSIQP-RLFECSSHAG---------------------------------------CLVLTEVL-FFGQEDLDKYDIMLLDTCQEIFLWLGEAAG-EWKKEAVAWGLEYLRTHPAERSLATPIFVVKQGHEPATFTGWFVTWDPYKWMNSQSYEEMVGNSLGPGSAISEMTAEVHNFQLTPRLSDNKAGHPALQAFKGSQDSPENELGLDLRVDGANPSMNHTSSCSDSMVNGSLPRERLMHQALEDLPPGVDPARKEFYLSDSDFQDIFGKSKEEFYSMAKWKQQQAKKKLGFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15195-1", "uniprot_id": "VILL_HUMAN", "id": "O15195-1", "name": "Villin-like protein", "aln": "-------------------------------------------MDISKGLPGMQGG-------------------------------LHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQS------------PKATQGASSDLHYWVGKQAGAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGII-YRKGGLASDLKHVETNLF--NIQRLLHIKGRKHVSATEVE-LSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAP--DLMQIMEAVLGRRVGSLRAATPSKDINQLQ---KANVRLYHVYEKGKDLVVLELATP-PLTQDLLQEEDFYILDQG-GFKIYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTY-TNVEVVNDGAESAAFKQLFRTWSEK-----RRRNQKLGGRDKSIHVKLDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV---------QYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQE---------HVTMGSEPPHFLAIFQG-QLVIFQERAGH--HGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTA-SVCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRAPYPSNKRLPEEVPSFQP-RLFECSSHMG---------------------------------------CLVLAEVG-FFSQEDLDKYDIMLLDTWQEIFLWLGEAAS-EWK-EAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTSHPSHKEVVDGSPAAASTISEITAEVNNLRLSRWPGNGRAGAVALQALKGSQDSSENDLVRSPKSAGSRTSS--SVSSTSATINGGLRREQLMHQAVEDLPEGVDPARREFYLSDSDFQDIFGKSKEEFYSMATWRQRQEKKQLGFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AYC4-1", "uniprot_id": "CAPG_RAT", "id": "Q6AYC4-1", "name": "Macrophage-capping protein", "aln": "----------------------------------MYTPIPQSGS------PFPAS---------------------------VQDPGLHIWRVEKLKPVPIARENHGIFFSGDSYLVLHNGP--------------EEAS----HLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPQGLK-YREGGVESAFHKTTSGTTPAAIRKLYQVKGKKNIRATERA-LSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQG-KAQVEIITDGEEPAE------MIQVLGPKPALKEGNPEEDITADQT--NAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVADGFISRMRYSPN-TQVEILPQGRESPIFKQFFKDWK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24452-1", "uniprot_id": "CAPG_MOUSE", "id": "P24452-1", "name": "Macrophage-capping protein", "aln": "----------------------------------MYTPIPQSGS------PFPAS---------------------------VQDPGLHIWRVEKLKPVPIARESHGIFFSGDSYLVLHNGP--------------EEAS----HLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYYREGGVESAFHKTTSGARGAAIRKLYQVKGKKNIRATERP-LSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQG-KAQVEIITDGEEPAE------MIQVLGPKPALKEGNPEEDITADQTRPNAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCAQIYIWKGRKANEKERQAALQVADGFISRMRYSPN-TQVEILPQGRESPIFKQFFKNWK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40121-1", "uniprot_id": "CAPG_HUMAN", "id": "P40121-1", "name": "Macrophage-capping protein", "aln": "----------------------------------MYTAIPQSGS------PFPGS---------------------------VQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGP--------------EEVS----HLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLK-YQEGGVESAFHKTSTGAP-AAIKKLYQVKGKKNIRATERA-LNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQG-KAQVEIVTDGEEPAE------MIQVLGPKPALKEGNPEEDLTADKA--NAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPN-TQVEILPQGHESPIFKQFFKDWK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PW43-1", "uniprot_id": "A0A8M9PW43_DANRE", "id": "A0A8M9PW43-1", "name": "Macrophage-capping protein", "aln": "-------------------------------MEPDSDSMPEQAEGALQMQPFQAAPGQ--------------------FGDEVRQPGLYCWRVEKMKAVPLNQAEVGAFFNGDSYLVLDNRG--------------DQGA----DLHMWIGEKSSRDEQVACAMLATQLDNFLGGDPVQHRQVQGYESPEFMKLFPRGVS-YKEGGVESGFRRAQSGPG--PVQRLYQIKGKRNIRAKEVD-LSWQSFNKGDCFILDLGETIVSWIGSQANIFEKQKVREIASLIRDTDRHG-KAQITNVNEGEETQE------MLKVLGPVPELKESTPEEDSKADAS----NSASLYKVSDATGSMKLTKVSEKSPFAKDLLVRDDCFILDNGANGKIFVWKGSGANAEEKRVALKMADDFIQQMNYPKMKTQVEILPQGRETVIFKQFFQSWN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PU64-1", "uniprot_id": "E9PU64_RAT", "id": "E9PU64-1", "name": "Scinderin", "aln": "-------------------------------------------------MAQELQHPE--------------------FARAGKQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTK--------------SSRG-FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLK-YKAGGVASGLNHVLTNDL--TAKRLLHVKGRRVVRATEVP-LSWQSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVATGIRDNERKG-RSQLIVVEEGSEPPE------LMKVLGRKPELPDGDNDDDVIADIS--NRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLPEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLHKMNYSAN-TQIQVLPEGGETPIFKQFFKDWKDKDQSDGFGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRG-------------QIIYTWQGADATRDELTMSAFLTVQLDRSLGGQAVQV---------RVSQGKEPAHLLSLFKDKPLIIYKNGTSK--KGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGFIWIGKGASQEEEKGAEYVADVLK-CKTTRIQEGKEP-----------GMNSGT-LLE---EEETTRLHHCWKHRL---------------------------------------KIILLGFMAALTK-------------LEDSLLKKFRESSPRMTWPKMMSCYLMRGNRSSFGLAKMPMKLRKRNQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60604-1", "uniprot_id": "SCIN_MOUSE", "id": "Q60604-1", "name": "Scinderin", "aln": "-------------------------------------------------MAQELQHPE--------------------FARAGQQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTK--------------SSRG-FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLK-YKAGGVASGLNHVLTNDL--TAKRLLHVKGRRVVRATEVP-LSWESFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVAIGIRDNERKG-RSQLIVVEEGSEPSE------LMKVLGRKPELPDGDNDDDVVADIS--NRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLQKMKYSTN-TQIQVLPEGGETPIFKQFFKDWKDKDQSDGFGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRG-------------QIIYTWQGANATRDELTMSAFLTVQLDRSLGGQAVQV---------RVSQGKEPAHLLSLFKDKPLIIYKNGTSK--KEGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGFIWIGKGASQEEEKGAEYVADVLK-CKASRIQEGKEPEEFWNSLGGRGDYQTSP-LLETRAEDHPPRLYGCSNKTG---------------------------------------RFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESVKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSRW----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6U3-1", "uniprot_id": "SCIN_HUMAN", "id": "Q9Y6U3-1", "name": "Scinderin", "aln": "-------------------------------------------------MARELYHEE--------------------FARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAK--------------TSRG-FTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLK-YKAGGVASGLNHVLTNDL--TAKRLLHVKGRRVVRATEVP-LSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKG-RSELIVVEEGSEPSE------LIKVLGEKPELPDGGDDDDIIADIS--NRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKN-TQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRG-------------QIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQI---------RVSQGKEPVHLLSLFKDKPLIIYKNGTSK--KGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLK-CKTLRIQEGEEPEEFWNSLGGKKDYQTSP-LLETQAEDHPPRLYGCSNKTG---------------------------------------RFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FP1-1", "uniprot_id": "GELS_RAT", "id": "Q68FP1-1", "name": "Gelsolin", "aln": "MAPYCSS-LRSALLVLALCALS-PSHAATASRGRAQERAPQSRVSETRPSTMVVEHPE--------------------FLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQ--------------LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFQGYFKSGLK-YKKGGVASGFKHVVPNEV--VVQRLFQVKGRRVVRATEVP-VSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSG-RAQVHVSEEGSEPEA------MLQVLGPKPDLPQG-TEDTAKEDAA--NRRLAKLYKVSNSGGSMSVSLVADENPFAQSALRSEDCFILDHGRDGKIFVWKGKQANMDERKAALKTASDFISKMQYPRQ-TQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVLVDPATYGQFYGGDSYIILYNYRHGGRQ---------GQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQS---------RVVQGKEPAHLMSLFGGKPMIIYKGGTSR--DGGQTTPASTRLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTP-SAAYLWVGTGASDAEKTGALELLKVLR-AQHVQVEEGSEPDGFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIG---------------------------------------RFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDDYWSVDPLDRALAELAA--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13020-1", "uniprot_id": "GELS_MOUSE", "id": "P13020-1", "name": "Gelsolin", "aln": "MAPYRSS-LLCALLLLALCALS-PSHAATTSRGRAQERAPQSRVSEARPSTMVVEHPE--------------------FLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQ--------------LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLK-YKKGGVASGFKHVVPNEV--VVQRLFQVKGRRVVRATEVP-VSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSG-RAQVHVSEEGGEPEA------MLQVLGPKPALPEG-TEDTAKEDAA--NRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQ-TQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLGYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ---------GQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQS---------RVVQGKEPAHLMSLFGGKPMIIYKGGTSR--DGGQTAPASIRLFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTP-SAAYLWVGAGASEAEKTGAQELLKVLR-SQHVQVEEGSEPDAFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIG---------------------------------------RFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDNYWSVDPLDRALAELAA--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06396-1", "uniprot_id": "GELS_HUMAN", "id": "P06396-1", "name": "Gelsolin", "aln": "MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPE--------------------FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQ--------------LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLK-YKKGGVASGFKHVVPNEV--VVQRLFQVKGRRVVRATEVP-VSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSG-RARVHVSEEGTEPEA------MLQVLGPKPALPAG-TEDTAKEDAA--NRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQ-TQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQ---------GQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQS---------RVVQGKEPAHLMSLFGGKPMIIYKGGTSR--EGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTP-SAAYLWVGTGASEAEKTGAQELLRVLR-AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIG---------------------------------------RFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P366-1", "uniprot_id": "A0A8M9P366_DANRE", "id": "A0A8M9P366-1", "name": "Gelsolin", "aln": "----------------------------------------------------MVYHPE--------------------FERAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTIK--------------QTSGNLQYDLHFWLGDYCTQDESGSAAIFTVQMDDYLGGKPIQYREVQGHESKSFLGYFKKGLQ-YMQGGVASGFKHVVTNEV--VMQRVLQVKGRRVVRATEVP-VSWDSFNQGDCFILDLGNEIYQWCGSKSNRFEKLKATQLAKGIRDNERSG-RARVYVCDEGVEREK------MLEVLGEKPDLPEG-ASDDVKADAS--NRKMAKLYKVSDASGDMAIALVAAENPFTQSALESSDCFILDHGSDGKIFVWKGKDANMEERKAAMKAADEFIKKMGYPKH-TQVQILPEMGETPLFKQFFKNWRDVDQTEGMGVAYVSNSIAKIEKVPFDASTLHDSPAMAAQHGMIDSGNGEKQIWRIEGSDKVPVDPSTYGQFYGGDSYIILYSYRHGGRQ---------GHIIYIWQGADSTQDEIGASAILGAQLDDELGGGPVQMAGAPLTTQVRVVQGKEPAHLMSLFGGQPMVVHKGGTSR--EGGQTAPAETRLFQVRSNSAGCTRAVEIDAVSSNLNSNDAFVLVTP-AASFIWVGQGASDIEKRGAQQLCGILG-VSPSELSEGGEDGGFWDALGGKAAYRTSSRLKDK-MNAHPPRLFACSNKTG---------------------------------------RFIIEEVPGEMTQEDLATDDVMILDTWDQVFVWIGNEAHDEEKMEAMTSAAQYIQTDPANRDPRTAIVKIKQGFEPPTFTGWFLGWDHDYWSTDPLERAMAELEI--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23989-1", "uniprot_id": "QUAI_DROME", "id": "Q23989-1", "name": "Villin-like protein quail", "aln": "---------------------------------MELSLSPKETEIRPNTIPDLKVDATFR-------------------KVAKHAITFAIWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNVSEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYD-VRSGALISAPQR----------PRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIER----RSALDWVQKHCSG--SPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYAD-YNSNKFRIYKCNQR-GRLHLDQLDVGMPAKDDLSDAHGVYLLDNY-GQSIWLWVGGQAPQADALSAMGNGRAFVKKKKYPDN-TLVVRVLEGHEPVEFKRLFANWLNVWQENTRGHKPVSTKFG-----KLDAHSLCERPKMAADTQLVDDGRGERVIYRVFGDQVQEVPISKTVVFTTNASFVVKYSVQCATVVPADLASVGIKTIIYQWNGSEASVESISRADKFAKASFDGLKEPGMFV---------QLYEFDEPPHFLQIFEGKLIIRRGQRTEMPYNGNSNALLDTFLLKVYGDASYNAKAVEET-HLSSISSKDCYVIKTN--HVWVWCGQSSTGDAREMAKAVGALMG--ENSLVLEGKESKEFWQSVAMYFNQTLVINGNGNSCSSSTSSSSGAGSMCNGSSNGGNISPTLSNNCYLNTSVPSKPRPPVQLFLVWWQQSSLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQERYTAIAQS--YVQNAPFGRRSATALAVVRQFQEPNVFKGFFESWQNDYGKNFHSYEKMRKDLGNKVTSNCCFASEGSALILNNRQKDFDG--------------------------------------------HKKYPLTVLIQEMDMLPPDINPLKREVHLTHDDFVSVFNMSFYEFDELPKWKKMELKKQFKLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * *: .*:: :* *:*. : :: : . *: * ** * * * *. * :: :: . : : . * :.*. ** . :::: . * * . *: : . * : : : : : . :* : : : : * ::**: .* :* * : : :: . :: *. * : : *. *:::* * ", "identical_positions": 37, "similar_positions": 67, "identity": "3.61%" }, { "cls_id": "homologset.agr.FB:FBgn0003189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMM2-1", "uniprot_id": "A0A8I5ZMM2_RAT", "id": "A0A8I5ZMM2-1", "name": "Multifunctional protein CAD", "aln": "MVPPLTCMVPPLTLPAACAVAVVLQLTTLRAPACRSRLLSSAPRSEPRGPTPARGVCLVPVGLAAPPASRCSPCLSSDPMAALVLEDGSVLQGRPFGAAVS-------TAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIP---SDEEDEFGLSKWFESSE--IHVAGLVVGECCPTPSHWSATCTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQKGTEPS-----------ALP---FVDPNARPLAPEVSIKTPRVFNA--------------GGAPRIFAVDCGLKYNQIRCLCQLGAEVTVVPWNHELDSRKYDGLFLSNGPGDPASYPGVVSTLNRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVDADSLPAGWAPLFTNANDCSNEGIVHDNLPFFSVQFHPEHRAGPSDMELLFDVFLETVRDTVAGNAEGRTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGG-TAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDV----ELETPTDKRIFVVAAALWAG-YSVERLYELTRIDCWFLHRMKRIVTHAKLLEQHRG--RPLPQDLLHQAKCLGFSDKQIALAVLSTELVVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVESVGLMTG-SGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECP---PQRSILDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHK--EDFASGTAAALAGGVTMVCAMPN--TRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLNETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLTRRSVHICHVARKEEILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVIDCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPLQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQG--AVPQPPPPTPTTTEITTTPERPRRVIPG-------------LPDGRFHLPPRIHRASDPGLPAMYLRPGAGISWGSRAWAEEPKEKPPRKVAESELIGTPDGPCYPVPPVPRQASPQNLGSSGLLHPQMSPLLHSLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILK-GKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPSSVWDFVASRGTK-QEEFESIEEALPDTDVLYMTRIQKERFGSSQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RQC6-1", "uniprot_id": "PYR1_MOUSE", "id": "B2RQC6-1", "name": "Multifunctional protein CAD", "aln": "-------------------------------------------------------------------------------MAALVLEDGSVLQGRPFGAAVS-------TAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIP---SDEEDEFGLSKWFESSE--IHVAGLVVGECCPTPSHWSANCTLHEWLQQRGIPGLQGVDTRELTKKLREQGSLLGKLVQKGTEPS-----------ALP---FVDPNARPLAPEVSIKTPRVFNA--------------GGAPRICALDCGLKYNQIRCLCQLGAEVTVVPWDHELDSQKYDGLFLSNGPGDPASYPGVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVDADSLPAGWAPLFTNANDCSNEGIVHDSLPFFSVQFHPEHRAGPSDMELLFDVFLETVREAAAGNIGGQTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITLHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGG-TAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDM----ELETPTDKRIFVVAAALWAG-YSVERLYELTRIDCWFLHRMKRIVTHAQLLEQHRG--QALPQDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRAPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCHTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMTG-SGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPEKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECP---PQRSILDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHK--EDFASGTAAALAGGVTMVCAMPN--TRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLNETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAVLMVAQLTQRPVHICHVARKEEILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVIDCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPLQEDTYVEVDLEHEWTVPSHMPFSKARWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQG--VVPQPPPSTPATTEITTTPERPRRVIPG-------------LPDGRFHLPPRIHRASDPGLP-----------------AEEPKEKPPRKVVEPELMGTPDGPCYPAPPVPRQASPQNLGSSGLLHPQMSPLLHSLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILK-GKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVIVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPPSVRDFVASRGTK-QEEFESIEEALPDTDVLYMTRIQKERFGSVQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27708-1", "uniprot_id": "PYR1_HUMAN", "id": "P27708-1", "name": "Multifunctional protein CAD", "aln": "-------------------------------------------------------------------------------MAALVLEDGSVLRGQPFGAAVS-------TAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIP---PDEMDEFGLCKWFESSG--IHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQNGTEPS-----------SLP---FLDPNARPLVPEVSIKTPRVFNT--------------GGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGG-TAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDM----ELETPTDKRIFVVAAALWAG-YSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRG--QPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTG-SGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECP---PQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHK--EDFASGTAAALAGGITMVCAMPN--TRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQG--AVPQLPPSAPATSEMTTTPERPRRGIPG-------------LPDGRFHLPPRIHRASDPGLP-----------------AEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHSLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILK-GKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPPTVRAFVASRGTK-QEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AL15-1", "uniprot_id": "A0A8M3AL15_DANRE", "id": "A0A8M3AL15-1", "name": "Multifunctional protein CAD", "aln": "---------------------------------------------------------------------------MSLKMASLVLEDGTTFKGRLFGAVSS-------VSGEVVFQTGMVGYPEALTDPSYKSQILTLTYPMIGNYGIP---KDEDGEFGLSKWFESSQ--IHAAALIVGEVSENPSHWSAAKSLDEWLREQGIPGLQGVDTRCLTKKIREKGTMLGKLVVEGTPAD-----------NIP---FDNPDARNLVKEVSMKAPKVFNP--------------EGTVRITAIDCGIKYNQIRCLCQRGARVTVVPWDQPLDSNDFDGLFISNGPGNPEYCKETVENIRKVACVENPKPIFGICLGHQLLSLVIGAKTYKMKYGNRGHNQPCIHKGTSRCYITSQNHGFAVDPETLPKDWDVLFTNANDQTSEGIVHNHKPLFSVQFHPEHMAGPTDLVGLFDVFLDTVRDVKE-NKAGKSVKQRLMEHLTFPGSPDP-NAFVRPRKVLVLGSGGLSIGQAGEFDYSGSQAIKAMKEENIQTILINPNIATVQTSKGLADKVYFLPITPEYVTQVIKNERPDGVLLTFGGQTALNCGVELKKQGVLEKYKVRVLGTPVASIEMTEDRKIFVEKMEEINEHVAPSEAAMSVEQAVAAAERLGYPVLVRSAFALGGLGSGFANNRDEMITLVTQAFAHTSQVLVDKSLKGWKEIEYEVVRDAYDNCVTVCNMENIDPLGIHTGESIVVAPSQTLNDYEYNMLRNTAIKVIRHLGVVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLSLGIPLPVLKNSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRSFEEAFQKALRMVDENCVGFDHTIKPESEE----ELQTPTDKRIFVLAAALHAG-YTVERLYELTKIDHWFLHKMKNIADHKKLLETYKQDESAMPPEIMRKAKQLGFSDKQIAQAVQSTELAVRKLRRDWKIFPVVKQIDTVAAEWPAQTNYLYLTYHGSESDVVFEQPHVMVIGSGVYRIGSSVEFDWCAVGCIMELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYEMENPEGVILSMGGQLPNNIAMSLHRQQCRILGTSPEFIDNAENRFKFSRMLDTIGISQPRWKELSDTESAVNFCETVGYPCLVRPSYVLSGAAMNVAYSDTDMEKFLSSAVAVSKEHPVVISKFIQEAKEIDVDAVACDGEVIAIAVSEHVENAGVHSGDATLVTPPQDINQKTMERIKMIVHAIGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPYVSKTLGVDLVALATRVILGEEVEAVGLMRG-NGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNILLSIGSYKNKSELLPTVQTLESLGYNLYASLGTADFYTEHGVKVMAVDWPFEEESD--CPNKDKQRNIMDYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDFSVPLITDIKCTKLFVQALKQIGQAPRVKTHVDSMTSQKLIRLPGLIDVHVHLREPGATHK--EDFSSGTAAALAGGITMVCAMPN--TNPAIIDPNSFTMAQKLAKAGCRCDYALFVGASSDNAALLPSIASSTAGLKMYLNDTYSTLKMDNVSLWMEHFEKWPKHLPIVAHAEKQTVAAILLVAQLYQRPVHICHVAKKEEILIIRAAKQKGIQVTCEVAPHHLFLCEDNVPVIGKDKAQVRPMLGTREDMEALWENLDIIDCFATDHAPHSAEEKISEKPPPGYPGLETMLPLLFTAVSEGRLTVDDIIKRLYENPRKIFSLPAQEDTYVEVDLEQEWIIPKHMQFTKSKWTPFEGMKVKGKVMRVVLRGEVAYIDGQVLVPPGYGQDVKSWSATPTATTEVIMDAPKRVIEAMTPERPRQAAPVDVVRSRAPSPRRSAGDGRFILPPRIHRSSDPGLPPGFKR-----STMHPQKAFAEEEVSLRAPFDAELALPAEAYAHP-PPLARILSPQAGQPQILPHPQTSPLLHPLVGQHILSVRQFSKEQMSHLFNVAHTLRLMVQKERPLDILK-GKVMASMFYEVSTRTSSSFAAAMHRLGGSVVHFCESTSSTQKGESLVDSVNTMSCYADVIVLRHPIPGAVESAARHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLARLLTQYRITLRYVAPKNLSMPAEIIDFVASKGIK-QEEFNSIEEALPDTDVLYMTRIQKERFSSEKEYNACFGQFILTPHIMTGAKRKMVVMHPLPRVNEISVEVDTDPRAAYFRQAENGMYIRMALLATVLGR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05990-1", "uniprot_id": "PYR1_DROME", "id": "P05990-1", "name": "Multifunctional protein r", "aln": "---------------------------------------------------------------------------MASTDCYLALEDGTVLPGYSFGYVPSENESKVGFGGEVVFQTGMVGYTEALTDRSYSGQILVLTYPLIGNYGVP---APDEDEHGLPLHFEWMKGVVQATALVVGEVAEEAFHWRKWKTLPDWLKQHKVPGIQDIDTRALTKKLREQGSMLGKIVYEKPPVE-----------GLPKSSFVDPNVRNLAKECSVKERQVYGNPN------------GKGPRIAILDCGLKLNQLRCLLQRGASVTLLPWSARLEDEQFDALFLSNGPGNPESCDQIVQQVRKVIEE-GQKPVFGICLGHQLLAKAIGCSTYKMKYGNRGHNLPCLHRATGRCLMTSQNHGYAVDLEQLPDGWSELFVNANDGTNEGIVHASKPYFSVQFHPEHHAGPQDTEFLFDVFMESIQ------QKDLTIPQLIEQRLR-PTTPAIDSAPVMPRKVLILGSGGLSIGQAGEFDYSGSQAIKAMRESNIQTVLINPNIATVQTSKGMADKCYFLPLTPHYVEQVIKSERPNGVLLTFGGQTALNCGVQLERAGVFSKYNVRILGTPIQSIIETEDRKLFAERVNEIGEQVAPSEAVYSVAQALDAASRLGYPVMARAAFSLGGLGSGFANNEEELQSLAQQALAHSSQLIVDKSLKGWKEVEYEVVRDAYNNCITVCNMENFDPLGIHTGESIVVAPSQTLSDREYQMLRSTALKVIRHFGVVGECNIQYALCPHSEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGLPLPDIKNSVTGNTTACFEPSLDYCVVKIPRWDLAKFVRVSKHIGSSMKSVGEVMAIGRNFEEAFQKALRMVDSDVLGFDPDVVPLNKEQLAEQLSEPTDRRPFVIAAALQLG-MSLRELHQLTNIDYWFLEKLERIILLQSLLTRNGS---RTDAALLLKAKRFGFSDKQIAKYIKSTELAVRHQRQEFGIRPHVKQIDTVAGEWPASTNYLYHTYNGSEHDVDFPGGHTIVVGSGVYRIGSSVEFDWCAVGCLRELRKLQRPTIMINYNPETVSTDYDMCDRLYFEEISFEVVMDIYEMENSEGIILSMGGQLPNNIAMDLHRQQAKVLGTSPESIDCAENRFKFSRMLDRKGILQPRWKELTNLQSAIEFCEEVGYPCLVRPSYVLSGAAMNVAYSNQDLETYLNAASEVSREHPVVISKFLTEAKEIDVDAVASDGRILCMAVSEHVENAGVHSGDATLVTPPQDLNAETLEAIKRITCDLASVLDVTGPFNMQLIAKNNELKVIECNVRVSRSFPFVSKTLDHDFVATATRAIVGLDVEPLDVLHG-VGKVGVKVPQFSFSRLAGADVQLGVEMASTGEVACFGDNRYEAYLKAMMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKMGYKLYASMGTGDFYAEHGVNVESVQWTFDKTTPDDING--ELRHLAEFLANKQFDLVINLPMSGGGARRVSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRMNGGKPPMKTHTDCMTSRRIVKLPGFIDVHVHLREPGATHK--EDFASGTAAALAGGVTLVCAMPN--TNPSIVDRETFTQFQELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGTLKLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKGVKVTCEVCPHHLFLSTKDVERLGHGMSEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSERPPPGFPGVETILPLLLQAVHEGRLTMEDIKRKFHRNPKIIFNLPDQAQTYVEVDLDEEWTITGNEMKSKSGWTPFEGTKVKGRVHRVVLRGEVAFVDGQVLVQPGFGQNVRPKQSP-LASEASQDLLPSDNDANDTFTRLLTSEGP--------------GGGVHGISTKVHFVDGANFLR-------------------PNSPSPRIRLD-------------------SASNTTLREYLQRTTNSNPVAHSLMGKHILAVDMFNKDHLNDIFNLAQLLKLRGTKDRPVDELLPGKIMASVFYEVSTRTQCSFAAAMLRLGGRVISMDNITSSVKKGESLEDSIKVVSSYADVVVLRHPSPGAVARAATFSRKPLINAGDGVGEHPTQALLDIFTIREEFGTVNGLTITMVGDLKNGRTVHSLARLLTLYNVNLQYVAPNSLQMPDEVVQFVHQRGVK-QLFARDLKNVLPDTDVLYMTRIQRERFDNVEDYEKCCGHLVLTPEHMMRAKKRSIVLHPLPRLNEISREIDSDPRAAYFRQAEYGMYIRMALLAMVVGGRNTAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07259-1", "uniprot_id": "PYR1_YEAST", "id": "P07259-1", "name": "Multifunctional protein URA2", "aln": "-----------------------------------------------------------MATIAPTAPITPPMESTGDRLVTLELKDGTVLQGYSFGAEKS-------VAGELVFQTGMVGYPESVTDPSYEGQILVITYPLVGNYGVPDMHLRDELVEELPRYFESNR--IHIAGLVISHYTDEYSHYLAKSSLGKWLQNEGIPAVYGVDTRSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQNLVSKVSINEPKLYVPPADNKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKVVPWNYDFTKEDYDGLFISNGPGDPSVLDDLSQRLSNVLEA-KKTPVFGICLGHQLIARAAGASTLKLKFGNRGHNIPCTSTISGRCYITSQNHGFAVDVDTLTSGWKPLFVNANDDSNEGIYHSELPYFSVQFHPESTPGPRDTEFLFDVFIQAVK-----EFKYTQVLKPIAFPGGLLEDNVKAHPRIEAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMK--DEFEALGVKVLGTPIDTIITTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAAYALGGLGSGFANNEKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDYCIIEVNARLSRSSALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPRWDLKKFTRVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDIDID---YELNNPTDMRVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGT-KEELPSLVLRQAKQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNADSHDLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDYDEADRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMIDSAENRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYSKNDLESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSGDATLIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNEIKVIECNVRASRSFPFISKVVGVNLIELATKAIMGLPLTPYPVEKLPDDYVAVKVPQFSFPRLAGADPVLGVEMASTGEVATFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLSSVQKLYNMGYKLFATSGTADFLSEHGIAVQYLEVLNKDDDDQKSE-----YSLTQHLANNEIDLYINLPSAN-RFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRN--ITLDVSERDAQTSHRTITLPGLINIATYVPNASHVIKGPAELKETTRLFLESGFTYCQLMPRSISGPVITDVASLKAANSVSQDSSYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRELK-----NKITAVAELLNQWPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNIYSLFIAQDDYP--------EAVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGMG-IKDSLPLLLAAVEEGKLTIDDIVLRLHDNPAKIFNIPTQ-DSVVEIDLDYSFRR-------NKRWSPFN-KDMNGGIERVVYNGETLVLSGELVSPGAKGKCIVNPSPASITASAELQSTSAKRRFSITEEAIADNLDA-------------AEDAIPEQPLEQKLMS---------------------------SRPPR----------------------ELVAPGAIQNLIRSN-------NPFRGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLDLMK-GHVITTIFFEPSTRTCSSFIAAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVPIINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRINLVSPPELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLYCTRVQEERFNSPEEYARLKDTYIVDNKILAHAKENMAIMHPLPRVNEIKEEVDYDHRAAYFRQMKYGLFVRMALLAMVMGVDM---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:**:.: * ** * .**:*********.*::** **..***.:***::****:* : * ** :: :.*::.. *: :* .**::. :*.: .:*** ***::*: *::**:: : . . : : :*:.: *. : *:: ::: ** :* *:* **:**: : *. :.::**. : ...::.**:*****:* . : .* *:*********:: . *..* *:::****** ** :.** :******:**: : *. .* **.**** :.*** * * ******** .** * ***:*::::: : : : .:***:************************::*..* *:********:***:*:*** **:*:* .:* :** ***:.: :********. *: : . : *::****: :* ****. * : **.*: * *:*. *: :* *...:*:**:.*:*::*********....*: * *:: :.*::::**:*****:********:.**:*******:********:**********.* :*::** **::* :*:*:*****:**** * *::* *************************.****.*.:** ::**** . * ****:******:***** ** ***..:.*.********.***.****:***:* .: :**: . :*. *** * *.:* *: :: .: ::*.** ***.::. : . : :: :** :**.*:*** : *.*:.:*: *:: * * ********.*:** ***** ** . *: * .:*:****************** .: ** ***:************ .*****: *.:* *:****:**..*:::***** .**:** ***:: ::*****: ** ****:****:** *: ** *:**:. :.* .*.. **** :*************..*:. *:* :*. * **:::****:*:: :****::**** :* : .:****************:.****: :*:: * . :.. *.:***:*:*:***::::********.*****::**.:. ::: **: *:* : . : . *.********.****** *****:****** **..: *****::::***::*:: :**:***:*.* ***.::: * .:**.*:*: **.** :***: * :: .. : : * ::.::* ***. . ** :*::::**:***:* *:*:**: ::**:**::::: . . *. **:: : ***:*:: .:: :.. . * :: . * * .*.* **. : * * * :: :.::: .. *::: :..: .* : *. . .* : *.: ..: . :. ** . ::..*: *:::::: * *.:** *:.**:: :* :.* :. ***:* : **: .: * : :* * :*:*: ** *: . * : : . : * :: ****: ** **:*:::*: ::: ** ** :* * :: **:**: .: : *:**: .::* : *** .**. :.*::: . *: : . . * .. . . : . . . * : :.: *:***:: *.:..: :* :*: *: :: :* : *::::::*:* **** .** *** **** :: . .**.:***:* *::..::.*:*.:*:**. :* ** .. *:**.*:* ******:**:******:*****:*:*::****:*******. ** *.: :. *:* .* :* : : . * . . :..***** **:*.***.. ::* . :: . : **.. ::**:**:***. *:* * ******* : *:::****** *:* ", "identical_positions": 896, "similar_positions": 640, "identity": "37.36%" }, { "cls_id": "homologset.agr.FB:FBgn0003204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24547-1", "uniprot_id": "IMDH2_MOUSE", "id": "P24547-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGGTSYVP--------------DDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU28-1", "uniprot_id": "IMDH2_RAT", "id": "E9PU28-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGGTSYVP--------------DDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNESDELVAIIARTDLKKNRDYPLASKDT-KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHGLHSYEKRLF------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12268-1", "uniprot_id": "IMDH2_HUMAN", "id": "P12268-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGGTSYVP--------------DDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXP9-1", "uniprot_id": "IMDH2_DANRE", "id": "B0UXP9-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGQTGYVP--------------DDGLTGQQLFNSGD--GLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTESGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKARHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDS-RKQLLCGAAIGTHNDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLIDAGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAKALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMD----KNLGSQTRYFSESDKIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTMSAQMEGGVHSLHSYEKRLF------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50096-1", "uniprot_id": "IMDH1_MOUSE", "id": "P50096-1", "name": "Inosine-5'-monophosphate dehydrogenase 1", "aln": "--------MADYLISGGTGYVP--------------EDGLTAQQLFANAD--GLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDS-HKQLLCGAAVGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLZ7-1", "uniprot_id": "IMDH1_RAT", "id": "D3ZLZ7-1", "name": "Inosine-5'-monophosphate dehydrogenase 1", "aln": "--------MADYLISGGTGYVP--------------EDGLTAQQLFANAD--GLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDS-HKQLLCGAAVGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20839-1", "uniprot_id": "IMDH1_HUMAN", "id": "P20839-1", "name": "Inosine-5'-monophosphate dehydrogenase 1", "aln": "--------MADYLISGGTGYVP--------------EDGLTAQQLFASAD--GLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS-QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGV1-1", "uniprot_id": "IMDH3_DANRE", "id": "Q5RGV1-1", "name": "Inosine-5'-monophosphate dehydrogenase 1b", "aln": "--------MADYLISGGTGYIP--------------DDGLSAQQLFAVGD--GLTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVLEAKVRHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAGVTLKEANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDS-RKQLLCGAAIGTREDDKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVKALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KNTSSQKRYFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFEKRTMSAQVEGGVHGLHSFEKRLY------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6GMG5-1", "uniprot_id": "IMDH1_DANRE", "id": "Q6GMG5-1", "name": "Inosine-5'-monophosphate dehydrogenase 1a", "aln": "--------MADYLISGGTGYVP--------------EDGLTAQQLFAIGD--GLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKVRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLKEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDS-RKQLLCGAAIGTREDDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KNNSSQKRYFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTMSAQVEGGVHGLHSYSFLPFTRNGYIEPGSRGHPRAGPNVPSPAVTKHSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07152-1", "uniprot_id": "IMDH_DROME", "id": "Q07152-1", "name": "Inosine-5'-monophosphate dehydrogenase", "aln": "MESTTKVKVNGFVESTSSSAAPAIQTKSTTGFDAELQDGLSCKELFQNGE--GLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDFR-ENQPEVLLADIMTT--ELVTAPNGINLPTANAILEKSKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKDS-NKQLLVGAAIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFSYEKRLF------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50095-1", "uniprot_id": "IMDH3_YEAST", "id": "P50095-1", "name": "Inosine-5'-monophosphate dehydrogenase 3", "aln": "-----MAAVRDYKTALEFAKSLP------------RLDGLSVQELMDSKTRGGLTYNDFLVLPGLVDFPSSEVSLQTKLTRNITLNTPFVSSPMDTVTESEMAIFMALLGGIGFIHHNCTPEDQADMVRRVKNYENGFINNPIVISPTTTVGEAKSMKERFGFSGFPVTEDGKRNGKLMGIVTSRDIQFVEDNS--LLVQDVMTK--NPVTGAQGITLSEGNEILKKIKKGKLLIVDDNGNLVSMLSRTDLMKNQNYPLASKSATTKQLLCGAAIGTIDADKERLRLLVEAGLDVVILDSSQGNSIFQLNMIKWIKETFPDLEIIAGNVATREQAANLIAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCEFANQFGIPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYQDGKRLKAYRGMGSIDAMQKTGTKGNASTSRYFSESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGYKSLTLLKENVQSGKVRFEFRTASAQLEGGVHNLHSYEKRLHN-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38697-1", "uniprot_id": "IMDH2_YEAST", "id": "P38697-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "-----MAAIRDYKTALDFTKSLP------------RPDGLSVQELMDSKIRGGLTYNDFLILPGLVDFASSEVSLQTKLTRNITLNIPLVSSPMDTVTESEMATFMALLGGIGFIHHNCTPEDQADMVRRVKNYENGFINNPIVISPTTTVGEAKSMKEKYGFAGFPVTTDGKRNAKLVGVITSRDIQFVEDNS--LLVQDVMTK--NPVTGAQGITLSEGNEILKKIKKGRLLVVDEKGNLVSMLSRTDLMKNQNYPLASKSANTKQLLCGASIGTMDADKERLRLLVKAGLDVVILDSSQGNSIFELNMLKWVKESFPGLEVIAGNVVTREQAANLIAAGADGLRIGMGTGSICITQEVMACGRPQGTAVYNVCEFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYQDGKRLKAYRGMGSIDAMQKTGTKGNASTSRYFSESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCRSLTLLKNNVQRGKVRFEFRTASAQLEGGVHNLHSYEKRLHN-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P50094-1", "uniprot_id": "IMDH4_YEAST", "id": "P50094-1", "name": "Inosine-5'-monophosphate dehydrogenase 4", "aln": "----MSAAPLDYKKALEHLKTYS------------SKDGLSVQELMDSTTRGGLTYNDFLVLPGLVNFPSSAVSLQTKLTKKITLNTPFVSSPMDTVTEADMAIYMALLGGIGFIHHNCTPKEQASMVKKVKMFENGFINSPIVISPTTTVGEVKVMKRKFGFSGFPVTEDGKCPGKLVGLVTSRDIQFLEDDS--LVVSEVMTK--NPVTGIKGITLKEGNEILKQTKKGKLLIVDDNGNLVSMLSRADLMKNQNYPLASKSATTKQLLCGAAIGTIEADKERLRLLVEAGLDVVILDSSQGNSVFQLNMIKWIKETFPDLEIIAGNVATREQAANLIAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCQFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYKDGKRLKAYRGMGSIDAMQKTGNKGNASTSRYFSESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCESLTSLKENVQNGEVRFEFRTASAQLEGGVHNLHSYEKRLYN-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : ***: ::*: ********:*** ::* :. *.* : **:.:*:. *::*********: ** *** ****:*******: ** *::** :::**: .* *:** * :. : : ** * *:* * .:*:*:::****:* :.. : : ** : *.. *:.* .* **:: ***:* :*:: . **::::*:** * :.:* ***.: **** **::** . ** ** ** * *:::********:::: *::::*:.:* ::::.***.* ** *** **.*.**:*** *********:*** **.*:**:*. :*.:**:* :****:*.:**:.**::**:*:****.:**.*:*:*****:.** *** ******::**: * . *..* *.: :******:: ****: :::*** *:**.***** .*:. :: : *:::* ** ***:**.**.*.*:. . ", "identical_positions": 238, "similar_positions": 157, "identity": "41.54%" }, { "cls_id": "homologset.agr.FB:FBgn0003205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08644-1", "uniprot_id": "RASK_RAT", "id": "P08644-1", "name": "GTPase KRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLP-SRTVDTKQAQELARSYGIPFIETSAKTRQRVEDAFYTLVREIRQY--------------------------------------------------------------------------------------------------------------------------RLKKIS-KEEKTPGCVKIKK-----CVIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32883-1", "uniprot_id": "RASK_MOUSE", "id": "P32883-1", "name": "GTPase KRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLP-SRTVDTKQAQELARSYGIPFIETSAKTRQRVEDAFYTLVREIRQY--------------------------------------------------------------------------------------------------------------------------RLKKIS-KEEKTPGCVKIKK-----CVIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01116-1", "uniprot_id": "RASK_HUMAN", "id": "P01116-1", "name": "GTPase KRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLP-SRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQY--------------------------------------------------------------------------------------------------------------------------RLKKIS-KEEKTPGCVKIKK-----CIIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01111-1", "uniprot_id": "RASN_HUMAN", "id": "P01111-1", "name": "GTPase NRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLP-TRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQY--------------------------------------------------------------------------------------------------------------------------RMKKLNSSDDGTQGCMGLP------CVVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04970-1", "uniprot_id": "RASN_RAT", "id": "Q04970-1", "name": "GTPase NRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLP-TRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQY--------------------------------------------------------------------------------------------------------------------------RMKKLNSSEDGTQGCMGLP------CVVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08556-1", "uniprot_id": "RASN_MOUSE", "id": "P08556-1", "name": "GTPase NRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLP-TRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQY--------------------------------------------------------------------------------------------------------------------------RLKKLNSSDDGTQGCMGSP------CVLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P79737-1", "uniprot_id": "RASN_DANRE", "id": "P79737-1", "name": "GTPase NRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADVHLYREQIKRVKDSDDVPMVLVGNICDL--ARTVDTKQAQELARSYGIEFVETSAKTRQGVEDAFYTLVREIRHY--------------------------------------------------------------------------------------------------------------------------RMKKLNSREDRKQGCLGVS------CEVM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P01112-1", "uniprot_id": "RASH_HUMAN", "id": "P01112-1", "name": "GTPase HRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH--------------------------------------------------------------------------------------------------------------------------KLRKLNPPDESGPGCMSCK------CVLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61411-1", "uniprot_id": "RASH_MOUSE", "id": "Q61411-1", "name": "GTPase HRas", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH--------------------------------------------------------------------------------------------------------------------------KLRKLNPPDESGPGCMSCK------CVLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AHV4-1", "uniprot_id": "A0A8I6AHV4_RAT", "id": "A0A8I6AHV4-1", "name": "small monomeric GTPase", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDSTIEDSYRKQVVIDGETCLMDILDTAGQEEYSAMRDQYMRTGKGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH--------------------------------------------------------------------------------------------------------------------------KLRKLNPPDESGPGCMSCT------CVLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08646-1", "uniprot_id": "RAS1_DROME", "id": "P08646-1", "name": "Ras-like protein 1", "aln": "-------MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLA-SWNVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKD--------------------------------------------------------------------------------------------------------------------------KDNKGRRGRKMNKPNRRFK------CKML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P01119-1", "uniprot_id": "RAS1_YEAST", "id": "P01119-1", "name": "Ras-like protein 1", "aln": "MQGNKSTIREYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNSMNRQLDNTNEIRDSELTSSATADREKKNNGSYVLDNSLTNAGTGSSSKSAVNHN------------GETTKRTDEKNYVNQNNNN----EGNTKYSSNGNGNRSDISRGNQNNALNSRSKQSAEPQKNSSANARKESSGGCCIIC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P01120-1", "uniprot_id": "RAS2_YEAST", "id": "P01120-1", "name": "Ras-like protein 2", "aln": "MPLNKSNIREYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINVEEAFYTLARLVRDEGGKYN--KTLTENDNSKQTSQDTKGSGANSVPRNSGGHRKMSNAANGKNVNSSTTVVNARNASIESKTGLAGNQATNGKTQTDRTNIDNSTGQAGQANAQSANTVNNRVNNNSKAGQVSNAKQARKQQAAPGGN-TSEASKSGSGGCCIIS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***:****.***********: *.:******.*************.:..::***************:****.*:*** *:::.. .*: :: * :** ****:: :*:*:*** ** *. .:. :*:. . ::***** *::***:* * :*. * * : ", "identical_positions": 93, "similar_positions": 47, "identity": "28.62%" }, { "cls_id": "homologset.agr.FB:FBgn0003206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62070-1", "uniprot_id": "RRAS2_HUMAN", "id": "P62070-1", "name": "Ras-related protein R-Ras2", "aln": "-MAAAGWRDGSGQ--------------EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIR----KFQ------------------------------------------------------------------------------------------------------------------------EQECPPSPEPTRKEKDKKGCHCVIF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJU0-1", "uniprot_id": "Q5BJU0_RAT", "id": "Q5BJU0-1", "name": "", "aln": "-MAAAGWRDGSGQ--------------EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIR----KFQ------------------------------------------------------------------------------------------------------------------------EQECPPSPEPTRKEKDKKGCHCVIF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62071-1", "uniprot_id": "RRAS2_MOUSE", "id": "P62071-1", "name": "Ras-related protein R-Ras2", "aln": "-MAAAGWRDGSGQ--------------EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIR----KFQ------------------------------------------------------------------------------------------------------------------------EQECPPSPEPTRKEKDKKGCHCVIF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10833-1", "uniprot_id": "RRAS_MOUSE", "id": "P10833-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVR----KYQ------------------------------------------------------------------------------------------------------------------------EQELPPSP-PSAPRKKDGGCPCVLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8L7-1", "uniprot_id": "RRAS_RAT", "id": "D3Z8L7-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFIEVSKLFTQILRVKDRDDFPIVLVGNKADLETQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRTVR----KYQ------------------------------------------------------------------------------------------------------------------------EQELPPSP-PSAPRKKDGRCPCVLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10301-1", "uniprot_id": "RRAS_HUMAN", "id": "P10301-1", "name": "Ras-related protein R-Ras", "aln": "MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVR----KYQ------------------------------------------------------------------------------------------------------------------------EQELPPSP-PSAPRKKGGGCPCVLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04388-1", "uniprot_id": "RAS2_DROME", "id": "P04388-1", "name": "Ras-like protein 2", "aln": "------------------------MQMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVR----KFQ------------------------------------------------------------------------------------------------------------------------IAER---PFIEQDYKKKGKRKCCLM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P01119-1", "uniprot_id": "RAS1_YEAST", "id": "P01119-1", "name": "Ras-like protein 1", "aln": "-MQGNKST------------------IREYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNSMNRQLDNTNEIRDSELTSSATADREKKNNGSYVLDNSLTNAGTGSSSKSAVNHN------------GETTKRTDEKNYVNQNNNN----EGNTKYSSNGNGNRSDISRGNQNNALNSRSKQSAEPQKNSSANARKESSGGCCIIC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P01120-1", "uniprot_id": "RAS2_YEAST", "id": "P01120-1", "name": "Ras-like protein 2", "aln": "-MPLNKSN------------------IREYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINVEEAFYTLARLVRDEGGKYN--KTLTENDNSKQTSQDTKGSGANSVPRNSGGHRKMSNAANGKNVNSSTTVVNARNASIESKTGLAGNQATNGKTQTDRTNIDNSTGQAGQANAQSANTVNNRVNNNSKAGQVSNAKQARKQQAAPGGN-TSEASKSGSGGCCIIS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::************:***: **:** :********* * :*. : ***********:.******** *.*****:::..: *: *: . ** **** * .*::::*** **. ::** .:. . . .::* *** :**::** * * :* *:: . . * :: ", "identical_positions": 85, "similar_positions": 49, "identity": "24.71%" }, { "cls_id": "homologset.agr.FB:FBgn0003210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIE5-1", "uniprot_id": "A0ABK0LIE5_RAT", "id": "A0ABK0LIE5-1", "name": "AP-3 complex subunit beta", "aln": "--MSSNSFAYNEQSGGGEAAELGQEATSTISSSGAFG---------LFSSDWKK----NEDLKQMLESNKDSAKLDAMKRIVGMIAKGKN---ASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPVMMLAIKEASADLSPYVRKNAAHAIQKLYSLD-PEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHRNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWRED------DGVEDN-EKNFYD-------------SDDEEK-----------KSGKKKP------YSMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPRSEAG--VISKSLVR--LLRSHREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVRSQDK--QFAAATIQTIGRCATSIAEVTDTCLNGLVCLLSNR--DEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSIT--VPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNE-KSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNVKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTP--LGKTKKEKPEKKFYSESEEEEEE------EEEDEEDEEEDPSDSSSDSESGSGRESGDSGSSSEDSSEDSSSGQDSETGSEAEAEHQRVAKTNSKTKR--------KSASEDREKKNGKSQASESSSE-ES---SSTEESSSESES--GSDSEP---APRKTAKAKE---RKPQQER----HPPSKDVFLLDLDDFNPVSTPVALP-TPALSP---SLIADLEGLNLSTSSSIINVSTPVFVPTKTHELLHRMRGKGLAAHYCFPRQPCIFGDKMVSVQITLTNTSDGKIENIHVGGKKLAVGVQMHVFHPIESLEPEGSVTVSMGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQASQGMLTGMNETSATLIAAPQNFTPSMIL-QKVVNVANLGAVPSSQD-NIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T1-1", "uniprot_id": "AP3B1_MOUSE", "id": "Q9Z1T1-1", "name": "AP-3 complex subunit beta-1", "aln": "--MSSNSFAYNEQSGGGEAAELGQEATSTISPSGAFG---------LFSSDWKK----NEDLKQMLESNKDSAKLDAMKRIVGMIAKGKN---ASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPVMMLAIKEASADLSPYVRKNAAHAIQKLYSLD-PEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHRNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWRED------GGLEDN-EKNFYE-------------SEEEEEEKE--------KSSRKKS------YAMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAG--VISKSLVR--LLRSNREVQYIVLQNIATMSIERKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVRSQDK--QFAAATIQTIGRCATSISEVTDTCLNGLVCLLSNR--DEIVVAESVVVIKKLLQMQPAQHGEIIRHMAKLLDSIT--VPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLAAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNE-KSGALSKYAKKIFLAPKPAPLLESPFKDRDRFQLGTLSHTLNIKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTP--LGKTKKEKPMKKFYSESEEEEDEDEDEDEEEEEKEDEDENPSDSSSDSESGSGSESGDTG--TEDSSEDSSSGQDSETGSQAEAERQKVAKRNSKTKR--------KSDSENREKKNENSKASESSSE-ES---SSMEDSSSESESESGSDSEP---APRNVAPAKE---RKPQQER----HPPSKDVFLLDLDDFNPVSTPVALP-TPALSP---SLIADLEGLNLSTSSSVINVSTPVFVPTKTHELLHRMHGKGLAAHYCFPRQPCIFSDKMVSVQITLTNTSDRKIENIHIGGKGLPVGMQMHAFHPIDSLEPKGSVTVSVGIDFCDSTQTASFQLCTKDDCFNVTLQPPVGELLSPVAMSEKDFKKE---QGTLTGMNETSATLIAAPQNFTPSMIL-QKVVNVANLGAVPSSQD-NVHRFAARTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00203-1", "uniprot_id": "AP3B1_HUMAN", "id": "O00203-1", "name": "AP-3 complex subunit beta-1", "aln": "--MSSNSFPYNEQSGGGEATELGQEATSTISPSGAFG---------LFSSDLKK----NEDLKQMLESNKDSAKLDAMKRIVGMIAKGKN---ASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLD-PEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKEG------DELEDN-GKNFYE-------------SDDDQKEK---------TDKKKKP------YTMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAG--IISKSLVR--LLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQDK--QFAAATIQTIGRCATNILEVTDTCLNGLVCLLSNR--DEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSIT--VPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNV-KSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVIELAKEWTP--AGKAKQENSAKKFYSESEEEEDS------------SDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKG--------KSDSEDGEKENEKSKTSDSSND-ES---SSIEDSSSDSESESEPESES---ESRRVTKEKE---KKTKQDR----TPLTKDVSLLDLDDFNPVSTPVALP-TPALSP---SLMADLEGLHLSTSSSVISVSTPAFVPTKTHVLLHRMSGKGLAAHYFFPRQPCIFGDKMVSIQITLNNTTDRKIENIHIGEKKLPIGMKMHVFNPIDSLEPEGSITVSMGIDFCDSTQTASFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKE---QGVLTGMNETSAVIIAAPQNFTPSVIF-QKVVNVANVGAVPSGQD-NIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVLSQG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58ICB1-1", "uniprot_id": "A0AC58ICB1_DANRE", "id": "A0AC58ICB1-1", "name": "AP-3 complex subunit beta", "aln": "--MNGGLGNLRLEAVGAMRSALVSAENLQLSLKSDLSSEEQALTNNHTSGNEEKPKRGNEDLKEMLESNKESLKLEAMKRVVGLIANGKN---ASELFPAVVKNVASKNIELKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAATDLSPYVRKTAAHAIQKLYSLD-PDQKEHLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFISPWRED------AIFDENSEKTFYD-------------SEEERR------------VDQSKP------YIMDPDHRLLLRNTKPLLQSRNTAVVMAVCQLYWHLAPKHEIS--IITKSLVR--LLRSHREVQYVVLQNIATMSIQRKGMFEPFMKSFYVRSTDATHIKTLKLEILTNLANEANISTILREFQTYVKSQDK--AFAAATIQAIGRCATNISEVTDTCLNGLVLLLSNR--DETVVAESVVVIKKLLQTQPSQHSDIIKHMAKLFDNIT--VPMARASILWLMGEYCEHVPKIAPDVLRKMAKSFTSEEDIVKLQTVNLAAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNE-KSGALSKYARRILMAPKPAPVLQSAFKDRDRYQLGTLSHTLNSQATGYLELSDWPAAAPDQSVRNVEVVEPVKESGAPSLGKSKAGKSKEKFYSDEEEEEEE------------EDEESNSEDSSSS-SSEESESGSESEENSEVSNKSSSSQSEKSSSESDSDKKKKTQKNKKIQQQ-------KPDSKNRKQKNGNAGKSESRSESESGSGSSSSESSSDSGSESGSELES---DSDSGTDQKKNTKSKPVQSKPVVKQVEKKEVSLLDLDDFAP--TPVTTPKSSILSP---SLLSDLQGLSISP-TSALQASSPVFVPETSYELLHRMTGKGLSGQYRFTRQPCIYDSSMVSLQLTLSNSSEQPLENIHISQK-SSCAQNIHCFNAVERLEPQASVTVSIGVNFNDSTQAANFQLCTKEDEFSVSIQPAVGELLLPVSMSEADFTRE---QGKLLGMNESSATITMSPENISSQSVS-RKVVSVANLGVISSTQE-NIHRFAGKTVSSSSLVLVSVTLKD-PDAQITVNTEKSVMGSMLLRQLKTALGNSAT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JME5-1", "uniprot_id": "AP3B2_MOUSE", "id": "Q9JME5-1", "name": "AP-3 complex subunit beta-2", "aln": "---MSAAPAYSEDKGG--SAGPGEPEYGHDPASGG-----------IFSSDYKR----HDDLKEMLDTNKDSLKLEAMKRIVAMIARGKN---ASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLD-SDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNE------SLLEENPEKAFYG-------------SEEDEAKGPGSEEAATAALPARKP------YVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVG--VIAKALVR--LLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDK--DFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNR--DELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQ--VPMARASILWLIGEYCEHVPKIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSE-QGGALSRHAKKLFLAPKPAPILESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNR-----EKRKEKEKPFYSDSEGESGP-------------TESADSEPESESESESKSSSGSGSGESSSESDNEE--EDEEKGGGSESEQ---SEEEDEKKK------------KTKKKKASEGHREGSSSE------EGSDSSSSS-ESEVTSESEE---EQVEPASWRK---KTPPGSKS---APVAKEISLLDLEDFTPPSVQPVSP-PMVVST---SLAADLEGLTLTDSSLVPSLLSPVSS-IGRQELLHRVAGEGLSVDYAFSRQPFSGDPHMVSLHIYFSNNSETPIKGLHVGTPKLPAGISIQEFPEIESLAPGESTTTVMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKE---QGKLTGMNEITEKLTLPDTCRSDHMVV-QKVTATANLGRVPCGTS-DEYRFAGRTLTSGSLVLLTLDARAAGAAQLTVNSEKMVIGTMLVKDVIQALTQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13367-1", "uniprot_id": "AP3B2_HUMAN", "id": "Q13367-1", "name": "AP-3 complex subunit beta-2", "aln": "---MSAAPAYSEDKGG--SAGPGEPEYGHDPASGG-----------IFSSDYKR----HDDLKEMLDTNKDSLKLEAMKRIVAMIARGKN---ASDLFPAVVKNVACKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLD-SDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNE------SLLEENAEKAFYG-------------SEEDEAKGAGSEETAAAAAPSRKP------YVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYFHLAPKAEVG--VIAKALVR--LLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDK--DFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNR--DELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQ--VPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTRQLIVPSE-QGGALSRHAKKLFLAPKPAPVLESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNR-----EKRKEKEKPFYSDSEGESGP-------------TESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQ---SEEDGKRK---------------TKKKVPERKGEASSSD------EGSDSSSSSSESEMTSESEE---EQLEPASWSR---KTPPSSKS---APATKEISLLDLEDFTPPSVQPVSP-PAIVST---SLAADLEGLTLTDSTLVPSLLSPVSG-VGRQELLHRVAGEGLAVDYTFSRQPFSGDPHMVSVHIHFSNSSDTPIKGLHVGTPKLPAGISIQEFPEIESLAPGESATAVMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSENEFKKE---QGKLMGMNEITEKLMLPDTCRSDHIVV-QKVTATANLGRVPCGTS-DEYRFAGRTLTGGSLVLLTLDARPAGAAQLTVNSEKMVIGTMLVKDVIQALTQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4K1-1", "uniprot_id": "Q9W4K1_DROME", "id": "Q9W4K1-1", "name": "AP-3 complex subunit beta", "aln": "MQQNSASNPFAMSTYVERPQMGLDVEFGADPASGAA----------FFQSDGRK----HDDLKQMLDSNKDGLKLEAMKRIIGMIARGRD---ASDLFPAVVKNVVSKNIEVKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVSMIVPIVMLAIRDSAADLSPYVRKTAAHAIPKLYSLD-ADQKDELVMVIEKLLSDRTTLVVGSAVMAFDEVCPERVDLIHKNYRKLCNFLLDVDEWGQVIIINMLTRYARTQFVDPNADDEDLVNDGLGETPVSERFYDESSHSSSHSDDGSSDDEKNKSSTNNKNNGGGNGSRTPSSPSNSYHIDVDHRLLLRQTKPLLQSRNASVVMAVAQLYHHVAPKNEVQ--LIAKALIR--LLRSHKEVQSVVLNCIASMSTKRKAIFEPHLKSFFVRTSDPTHIKLLKLDILTNLASAGSISLILREFQTYISSSDR--SFVAATIQAIGRCASSIKEVTETCLSGLVHLLSNH--DEHVVAESVVVIKRLLQTKAAEHFEIITQMAKLIDYIN--VPAARAAIIWLIGEYNEKVPLIAPDVLRKMAKSFVDEQDVVKLQVLNLGVKLYLTNPEQTSLLCQYVFTLARYDPNYDVRDRARFLRQIIFPASGTSSVLSQHARQVFLASKPAPVPESKYRDGNNFQLGSLSHYLNMPAAGYKELPAFPVIPPDSSVRNIAGFMQDKLPGE----DSPSGHSKDKSGREGGKEKGAG---------GEKGFLSESDDKSSAYSESGSSSGSGTSDSESDSDGSGSSDEEEEEVQKQQPTKVSSVKERLIDAGSNELAATSSPVKATINNNNNARGSSGTSDSED---SSAYSGSSSDDSASGSDNEVKKNETKTDTGTKPEKLKEKHEKQPEQTAVKSNLDLLLDLDDIPPIGPVMTPSLGGFLTPGTPMMAGQAAPLQPQHARNRVELVGPSHIEFKHKELLNKVSGHGLHLAYRFTRSPHLYSSSMCSIELQFQNRGEKEITAIRLGQTTLPAGMQLNEFAPITVLQPQQTASGVLGVDFNDSTHAVDLELLSSAGSSRLQLKPPVGELVRSVQIGESCHREE---RAKLRGMNEHQCELRGLRQDLIDVVALRQKVFESINVAHTHSSSSGQLHCFAGQTLSSKSLVLLTLDWKTEDALTLLVNCEKMVIGSMVLNELRNALQLSFAM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46682-1", "uniprot_id": "AP3B_YEAST", "id": "P46682-1", "name": "AP-3 complex subunit beta", "aln": "MVDSIHRIASALDTAKVITREAAAVATSKLGESSYT----------YYSQNINP-----QQLVTLLNSRNSREVRDAMKRIISIMASDDDSIDVQLYFADVVKNITTNDTKVKRLIHLYLLRFAENDPNLTLLSINSLQKSLSDSNSELRCFALSALSDMKMSSLAPIILHTVKKLVTDPSAMVRGEVALAIIKLYRAGKNDYHEELLDILKELMADTDPKVISCAVLAYKECYADHLELLHGHFRRYCRIIKQLDSWSQSYLIELLIKYCKQYLPKPTVVD------KSSEGSPRSCPLP----------------------------DKYNEIEYP---SYEVVNDPDLDLFLQSLNCLIYSSNPTVILSCCNALYQLASPLQMKNTKFIEALVRTVTMTENQGNKEMLLQAIHFLSILDQTLFLPYTKKFYVFPKDPIVASIWKIQILSTLINESNVKEIFKELKYYVASAHFPENVVIMAVKSLSRCGQLSTSWESHVMKWLIDHMESHNLSASVLDAYVNVIRMLVQKNPTKHLRIIFKLADLLTVQTSLADNARAGIVWLFGEIASIEFKICPDVLRRLIQNFSNEGPETRCQILVLSAKLLSYDIDNFKQAQVTGSEENNQNPPYYDFSGSRISQMYNAVLY-----LAKYDDEFDIRDR-ARMISSLFD------------------SGKYEIVSLLLQAPKPTARSDDFIVSARLETH--------TPEIKEFFR------------------------------MLPWNTEITEVGETGNDIREGAELKDYNKYKKS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSSQSFITNNSAR----SFTSSSNAKLTGINDGDS--------------------NSISGKGNVNTFTSQNGKKYRLQS-LDEFFSDIPERKSKPRKIIKVVEESSDED-----------EDESEESSDDDEYSD-----------SSLGTSSSGTS------------SSHLEL----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : . ::* :*::.:. :****::.::* . : .. *. ****:. :: ::*:*:::**:*:**:: :*:****.::*:.*.*.*. :*. ** .**.:::. :.*::: :::. :* *. ** .* ** *** . : :: *: ::::*: * . * ...*:*:.* .::::*:* ::*: *.:: :::.*.* :* :* :*.: : .* : . . * * *:::. : *: * ..:*::: .: :::. : : ::*:* : .: : ::*: : :* : :* *. *.*:: ..*. . *:::*:.* . .: :::*:: *: * . .. :::::.**. . :. *: :..: . *: * **: *:* :.::* ** ::*.* . ***.*:**:** . *.*****:: :.* * .: * : *..** : .: . . : * . :*: : *::: .. : : * : .* : :* *: .*. :.*. : . . . . . . . :: . . .: *. .. . : . : : :. . : : .:: * : . .* : : .: : : * .: * .:. . . . * * ", "identical_positions": 132, "similar_positions": 287, "identity": "10.94%" }, { "cls_id": "homologset.agr.FB:FBgn0003218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2N3-1", "uniprot_id": "PITM1_RAT", "id": "Q5U2N3-1", "name": "Membrane-associated phosphatidylinositol transfer protein 1", "aln": "MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGNGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYRSVKTGRGPLADDWARTAAQTG-----------PLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWIELSMADIRALEEETARMLAQRM---------------------AKCNTGSEGPEAQTPGKPSTETQPGTRTAGTPDGPEAPPGPDASPDASFGKQWSSSSRSSYSSQHGGGVSPQSL-------------------------SEWRMQNIARDSENSSEEEFFDAHEGFSDSDEVFPKEMTKWN-SNDFIDAFASPTEVEGVP---------------DPAIMATKGIEDEARAPRDSEGLDGTGDLG------VEACSVHALFLILHSGSILDSGPGDTNSKQADVQTLSTAFEAVTRVHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQD---HIPLAALPLLATSSSRYQGAVATVIARTNQAYAAFLRSSEGTGFCGQVVLIGDGVGGILGFDALCHSASAGTGS-RGSSRRGSMNNEM----LSPEVGPVRD------------------------PLADGVEVLGRASPEPS------ALPAQRTSSDMANPDPDGSQNSLQVAPTVTS-GEPRRASTASCPPASS-EAPDGPTNAARLDFKVSGFFLFGSPLGLVLALRKTVMPALEVAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLAVPRYQKFPLGDGSSLLLAD--------------------------------------------------TLQTHSSLFLEELE---------------MMVPSTPTSASG----------------------AFWKGNELGNEPAAQPAAPSTTSE-----------------VVKILDRWWGNKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKE-RPQLTECE--EPSIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLNGRFMYGPLDVVTLTGEKVDVYVMTQPLSGKWIHFGTEVTNSSGRLTFPVPSERALGIGVYPVRMVVRGDHTYAECCLTVVSRGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHAPSGPP-RAALAKSSYAVAAPVDFLR--------KQS-QLLRSRGPSQVDLE-------GPGTPPTTLARGKTRSISLKLDSEE------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35954-1", "uniprot_id": "PITM1_MOUSE", "id": "O35954-1", "name": "Membrane-associated phosphatidylinositol transfer protein 1", "aln": "MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGNGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRIVDTIDIVRDAVAPGEYKAEEDPRLYRSAKTGRGPLADDWARTAAQTG-----------PLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWIELSMADIRALEEETARMLAQRM---------------------AKCNTGSEGPEAQTPGKSSTEARPGTSTAGTPDGPEAPPGPDASPDASFGKQWSSSSRSSYSSQHGGGVSPQSL-------------------------SEWRMQNIARDSENSSEEEFFDAHEGFSDSDEVFPKEMTKWN-SNDFIDAFASPTEVEGVP---------------DPTVMATKGIEDGARAPRDSEGLDGAGDLV------VEACSVHALFLILHSGSILDSGPGDTNSKQADVQTLSTAFEAVTRVHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQD---HIPLAALPLLATSSSRYQGAVATVIARTNQAYAAFLRSSEGTGFCGQVVLIGDGVGGILGFDALCHSASAGPGS-RGSSRRGSMNNEM----LSPEVGPVRD------------------------PLADGVEVLGRASPEPS------ALPAQRTFSDMANPDPDGSQNSLQVASTATSSGEPRRASTASCPPASS-EAPDGPTNAARLDFKVSGFFLFGSPLGLVLALRKTVMPALEVAQLRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLAVPRYQKFPLGDGSSLLLAD--------------------------------------------------TLQTHSSLFLEELE---------------MMVPSTPTSASG----------------------AFWKGSELGNEPASQTAAPSTTSE-----------------VVKILDRWWGNKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKE-RPQLTECE--EPSIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLNGRFMYGPLDVVTLTGEKVDVYVMTQPLSGKWIHFGTEVTNSSGRLTFPVPSERALGIGVYPVRMVVRGDHTYAECCLTVVSRGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHAPSGPP-RAALAKSSYAVAAPVDFLR--------KQS-QLLRSRGPSQVDRE-------GPGTPPTTLARGKTRSISLKLDSEE------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00562-1", "uniprot_id": "PITM1_HUMAN", "id": "O00562-1", "name": "Membrane-associated phosphatidylinositol transfer protein 1", "aln": "MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGSGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYHSVKTGRGPLSDDWARTAAQTG-----------PLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWTELSMADIRALEEETARMLAQRM---------------------AKCNTGSEGSEAQPPGKPSTEARSAASNTGTPDGPEAPPGPDASPDASFGKQWSSSSRSSYSSQHGGAVSPQSL-------------------------SEWRMQNIARDSENSSEEEFFDAHEGFSDSEEVFPKEMTKWN-SNDFIDAFASPVEAEGTP---------------EPGAEAAKGIEDGAQAPRDSEGLDGAGELG------AEACAVHALFLILHSGNILDSGPGDANSKQADVQTLSSAFEAVTRIHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQD---HIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGFCGQVALIGDGVGGILGFDALCHSANAGTGS-RGSSRRGSMNNEL----LSPEFGPVRD------------------------PLADGVEGLGRGSPEPS------ALPPQRIPSDMASPEPEGSQNSLQAAPATTSSWEPRRASTAFCPPAASSEAPDGPSSTARLDFKVSGFFLFGSPLGLVLALRKTVMPALEAAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLTVPRYQKFPLGDGSSLLLAD--------------------------------------------------TLQTHSSLFLEELE---------------MLVPSTPTSTSG----------------------AFWKGSELATDPPAQPAAPSTTSE-----------------VVKILERWWGTKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKE-RPQLAECE--EPSIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLSGRFMYGPLDVVTLTGEKVDVYIMTQPLSGKWIHFGTEVTNSSGRLTFPVPPERALGIGVYPVRMVVRGDHTYAECCLTVVARGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHASSGPP-RAALGKSSYGVAAPVDFLR--------KQS-QLLRSRGPSQAERE-------GPGTPPTTLARGKARSISLKLDSEE------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BZ71-1", "uniprot_id": "PITM3_HUMAN", "id": "Q9BZ71-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKAGRAGGPPPGGG-------------------------APWHLRNVLSDSVESSDDEFFDAREEMAEGKNAILIGMSQWN-SNDLVEQIETMGKLDEHQGEGTAPCTSSILQEKQRELYRVSLRRQRFPAQGSIEIHEDSEEGCPQ-----RSCKTHVLLLVLHGGNILDTGAGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSHLNPYSHDEGCLSSSQD---HVPLAALPLLAISSPQYQDAVATVIERANQVYREFLKSSDGIGFSGQVCLIGDCVGGLLAFDAICYSAGPSGDSPASSSRKGSISSTQ----DTP-VAVEED------------------------CSLASSKRLSKSNIDISSGLEDEE-PKRPLPRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDESETPAAGGPQLPEVS--LGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGLDGFQVRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLAD--------------------------------------------------ALHTHSPLFLEGSS--------------RDSPPLLDAPAS-------------------------PPQASRFQRPGRRMSEGSSHSESSESS-----DSMAPVGASRITAKWWGSKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYE-SVNIKESARLDPAALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMAEPSSGRWVHLDTEITNSSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKISAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNS-RMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---AANPKPERAQSQPESDKDHERPLPALS----WARGPPKFESVP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8F6-1", "uniprot_id": "A0A8M1P8F6_DANRE", "id": "A0A8M1P8F6-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDRMTQETRVP-SRKHSA-------------------------SHWRLQNIAQESVESSDEEFFDARDVM-EGKTALLLEMSQWN-SNDLVEQIETLGHLEHS----------------RESLYR--LRHPRCAPQSSVDGLEDME----------RKCRTQLLILVIHGGHILDSGGGDPGGKAGDAATLASVLERVARAHFQAAADSMLVRLVPCPPVCADAFTLVSNLNPYSYDENCVSTSVD---HLPLAALPILAIAAPHYQNAVAAVIAQANQVYRNFLQSPEGVGFTGQVCLVADCVGGVLCFDALCFSGDKQHRSPEGGSTNNSTESLK----EKPGVVNSLS------------------------PTLRGSKRLSKSNIDVSTPCDVLSGIRHPLIRKQSDSCDADVASG-QREVFISSLSQ---DDQCGSRQALSP---------GCFEFEVSDCFLLGCPLGLVLAMRRTVVPGVDVAQLRPACSQIFNLFYPSDPSASRLEPLLHSVLTQLPPFPVPRYQRCPLGDGRSTLIVD--------------------------------------------------TVLRHVTEGGVSAD--------------GAADQCYGGSVS-------------------------RRGSDRAVPLG---SEGTAPSE--------------PVSISQVCSRWWGSKRLDYVLYCPDVLTTFPTIALPHLFHASYWESTDAVAFILRQVMRCD-CLKAGEADCSDAIPISPSSPREKWLRRRTHVKLRNITANHRVHDVIVTEDGPQTLVGRFMYGPLDMVTLTGEKVDVFLKTQSGSGRWVLFDTVVTSSSGRVSYTIPDNKRLGVGVYPIKMVVKGDQTSAEAFLTVLPQGMECVVFSIDGSFAASVSLMGSDPKVRPGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMVFFSEGLVHDPLRQKTIFLKSLVKECHIKISAAYGSMKDMSVYSTLGLAPNQIYIVGRPSKKHQHQCQFLSEGYAAHLSTLEFEHGSRSKKN---RMVLRQGSFGLSSKTDFLSPSPDFLSCKRTPLLRRAMSVQQPSPPSSSVSTPKPERAQSQPESHKDGPEIRIQYDDQDEEEEEEGRIQDVVL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AUE0-1", "uniprot_id": "A0A8I6AUE0_RAT", "id": "A0A8I6AUE0-1", "name": "", "aln": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENNNVFNLSPVEKNQLITDIIDIVKDPVTPSEYKTEEDPKLFQSIKTRRGPLSENWIQEYKKRLL----------PIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLTMEKIRELEKEVQLMLSRKM---------------------AQFSEEG--PSELSKESTIKDQATGATPE------PSSSNGESLG-RGLKKQWSTSSKSSRSSKRGASPSRHSI-------------------------SEWRMQSIARDSDESSEEEFFDAQENLQHKEEMYTKDITKWS-SNDLMDKMENPEPEESQ-----------------DSLYH--QSGSEFRVASSVEQLNTIEDEVSQP-LATPPSKIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFALVSNLSPYGHDEGCLSSSQD---HIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCYSGQPVSES-QSSSRRGSVVSMQDADLLSPGILVNAAHCSGGSGGGSGGG-----------SSLESSRHLSRSNIDIPRSNGTED-SRKQMPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFNIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHGDSFLETSIPVPALTWQDGPRQSLGCSESDALQTHNTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAESYTASGIAQKGPSSLNHTPSIRRLSLLALPPPSPTTQGPRARARQVSPNLERGPCLPDLDIGEVAAKWWGQKRIDYALYCPDALMAFPTVALPHLFHASYWESTDVVSFLLRQVMRHD-SASILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVAANHRINDAVANEDGPQVVTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLYLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVAVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLR--------SRN-HLLRTISAQPSGPS------HRHDRTQTQMDLEQRGQRSMSMAASCWGRAMAGRLEPGAATGPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPQ6-1", "uniprot_id": "PITM2_MOUSE", "id": "Q6ZPQ6-1", "name": "Membrane-associated phosphatidylinositol transfer protein 2", "aln": "MIIKEYRIPLPMTVDEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENNNVFNLSPVEKSQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTCRGPLSENWIQEYKKRLL----------PIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLTMEKIRELEREVQLMLSRKM---------------------AQFSEEG--PSELSKDSATKDQASGTTSD------PGSKNGEPLG-RGLKKQWSTSSKSSRSSKRGASPSRHSI-------------------------SEWRMQSIARDSDEGSEEEFFDAHENLYCTEEKQAKDMTKWN-SNDLMDKMESPEPEESQ-----------------DEIYQ--QSGSEFRVASSVEQLNIIEDEVSQP-LAAPPSKIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFALVSNLSPYGHDEGCLSSSQD---HIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCYSGQPVSES-QSSSRRGSVVSMQDADLLSPGTLANAAHCSGGSGGGGSGG-----------SSLESSRHLSRSNIDIPRSNGTED-SRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHSLPPFSIPRYQRYPLGDGCSTLLAD--------------------------------------------------VLQTHNTVFQEHAAPSSPGTAPAGRGFRRASEISIASQVSGMAESYTASSIAQKGPSSLNHTPSIRRLSLLALPPPSPTTQGPRARARQVSPNLERAPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHD-SSSILELDGKEVSVFTPSQPRERWQRKRTHVKLRNVAANHRINDAVANEDGPQVVTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLHLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPRGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVAVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQSDFLR--------SRN-HLLRTISAQPSGPS------HRHDRTQTQMDSEQRGQRSMSVAASCWGRAMAGRLEPGAATGPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZ72-1", "uniprot_id": "PITM2_HUMAN", "id": "Q9BZ72-1", "name": "Membrane-associated phosphatidylinositol transfer protein 2", "aln": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGEGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAGENPDVFNLSPVEKNQLTIDFIDIVKDPVPHNEYKTEEDPKLFQSTKTQRGPLSENWIEEYKKQVF----------PIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLSMENIRELEKEAQLMLSRKM---------------------AQFNEDGEEATELVKHEAVSDQTSGEPPE------PSSSNGEPLVGRGLKKQWSTSSKSSRSSKRGASPSRHSI-------------------------SEWRMQSIARDSDESSDDEFFDAHEDLSDTEEMFPKDITKWS-SNDLMDKIESPEPEDTQ-----------------DGLYR--QGAPEFRVASSVEQLNIIEDEVSQP-LAAPPSKIHVLLLVLHGGTILDTGAGDPSSKKGDANTIANVFDTVMRVHYPSALGRLAIRLVPCPPVCSDAFALVSNLSPYSHDEGCLSSSQD---HIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGMTFNGQVCLIGDCVGGILAFDALCYSNQPVSES-QSSSRRGSVVSMQDNDLLSPGILMNAAHCCGGGGGGGGGGGSSGGGGSSGGSSLESSRHLSRSNVDIPRSNGTED-PKRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRTEPCSRHSSSSTMLDGTGALGRFDFEITDLFLFGCPLGLVLALRKTVIPALDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHALPPFSVPRYQRYPLGDGCSTLLAD--------------------------------------------------VLQTHNAAFQEHGAPSSPGTAPASRGFRRASEISIASQVSGMAESYTASSIAQKAPDALSHTPSVRRLSLLALPAPSPTTPGPHPPARKASPGLERAPGLPELDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHD-NSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDALANEDGPQVLTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLYLDTLVTNNSGRVSYTIPESHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRVHAAYGSTKDVAVYSAISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYSHRARPARNTATRMALRKGSFGLPGQGDFLR--------SRN-HLLRTISAQPSGPS------HRHERTQSQADGEQRGQRSMSVAAGCWGRAMTGRLEPGAAAGPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43125-1", "uniprot_id": "RDGB_DROME", "id": "P43125-1", "name": "Protein retinal degeneration B", "aln": "MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHVGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFVEKFSLDIETYYYPDNGYQDNVFQLSGSDLRNRIVDVIDIVKDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQLALAKKMGGGEECSDDSVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEASSDEEGEEEEDDDEDENDAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKFGSKGALHSPVGSAHSFDLQVANWRMERLEVDSKSNSDEEFFDCLDTNETNSLAKWSSLELLGEGDDSPPPHGGPSSAASVGGRGNSRQEDSIFN--QDFLMRVASERGNKRQLRSSASVDRSHDSSPPGSPSTPSCPTTILILVVHAGSVLDAAS-ELTAKKSDVTTFRGSFEAVMRQHYPSLLTHVTIKMVPCPSICTDALGILSSLSPYSFDASPSAADIPNIADVPIGAIPLLSVASPEFHETVNKTVAAANIVYHEFLKSEEGHGFSGQIVMLGDSMGSLLAYEALCRSNGSQPGTASGASNSGGDAATN----------------------------------------INTHNPLSPRN-------------------SRLDDDERFIEADLDAKRLLVAPSPRRRRSSSSSDSRAT-----------KLDFEVCDFFMFGSPLSVVLAARK--LHDAKAALPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNVPRYAKYPLGNGQPLHLLE--------------------------------------------------VIQSHPQHFNDGNN------------------LLAG-----------------------------RRLSDASMQSTISGLIENVSLS----------------TIHALQNKWWGTKRLDYALYCPEGLSNFPAHALPHLFHASYWESPDVIAFILRQIGKFEGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKNVAANHRANDVIVQEGREQRLNARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGRISYSIPDQVSLGYGIYPVKMVVRGDHTSVDCYMAVVPPLTECVVFSIDGSFTASMSVTGRDPKVRAGAVDVCRHWQELGYLLIYITGRPDMQQQRVVSWLSQHNFPHGLISFADGLSTDPLGHKTAYLNNLVQNHGISITAAYGSSKDISVYTNVGMRTDQIFIVGKVGKKLQSNATVLSDGYAAHLAGLQAVGGSRPAKGNA-RMVIPRGCFNLPGQTANPR--------RRR-----------------------------YLERKTVSSCCLMVFQTT------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *::. : :* ..*::****. : . : . .:* . : . *:*::*.* :**:. : * .* *: :: * * *: : :::****.:*: * ::* *.**..* . : . .:*:.*:*:*: ::..:: :* .: :* .* *::* :* * **: ::.* :*.:* ::*:* * : ..* .. . *. . . . : : ::*.: . *::*.**.:*** *: : . ** * *::.:*: :** ******** : :.*. :*** : ***:* . : : .: * : :*** **:** ****: * **: :************.*.::*:***: . : . : *. ***:* ::** **::*:::*** *.:. *. * : .********:::* *****: : :. :*.* :.* :*...**::: :* ** *:**::***:**:* . . ::*:. * *********:**:*: * *****.***** ****: **:::*:*******::***:**:*****:*:: *.:** *** :*: :*. *:.: : *.*** **::** :.: . : :***: :* * :. .:::**.***. *: ::. . * : :..: : . : ", "identical_positions": 243, "similar_positions": 243, "identity": "16.17%" }, { "cls_id": "homologset.agr.FB:FBgn0003227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVK1-1", "uniprot_id": "MCM8_RAT", "id": "D3ZVK1-1", "name": "DNA helicase MCM8", "aln": "----------MSGAYRGRGFGRGRFQNWKRGRGGG---NFSGRWRDR---TDLSKAAGNHASEQASQPLLQ-------QSTLDQFIP------------------------YKGWKLYFS-EVYSNNSPLTEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTKDNEITNLIPDIENALRDAPEKTLACMGLAIHQVLT-KDLERHAAELQAQEGLCNGGGTMVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTKMAFQCAACGEIQSFPLPDGKYNLPTKCPVPACRGR-SFTPLRSSPLTVTMDWQLIKIQELMSDAQREAGR-IPRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRSKNDKCMFLLYIEANSVSNSKGQKAQTAEDGCKHGTLMEFSLKDLYAIQEIQAEENLLKLIVNSLCPVIFGHELVKAGLMLALFGGSQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTATSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQRAVSSATVSRVLSQDSNTSVLEVVSE-----------------------KPLSERLKVAPGE-KTDPIPHQLLRKYIGYARQYVHPRLSTEAAQALQDFYLELRKQS--QRVGSSPITTRQLESLIRLTEARARLELREEATKEDAEDIIEIMKHSMLGTYSDEFGNLDFERSQHGSG--MSNRSTAKRFISALNSIAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQLQTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWV1-1", "uniprot_id": "MCM8_MOUSE", "id": "Q9CWV1-1", "name": "DNA helicase MCM8", "aln": "----------MSGAYRGRGFGRGRFQSWKRGRGGG---NFSGRWRERENRVDLNEASGKHASAQASQPLLQ-------QSTLDQFIP------------------------YKGWKLYFS-EVYSNNSPFIEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTKADEITNLIPDIENALRDAPEKTLACMGLAIHQVLT-KDLERHAAELQAQEGLSNGGETMVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLPTKCPVPACRGR-SFAPLRSSPLTVTLDWQLIKIQELMSDAQREAGR-IPRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRNKNDKCMFLLYIEANSVSNSKGPKAQTAEDGCKHGTLMEFSLKDLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVSSATVTRVLSQDSNTSVLEVVSE-----------------------KPLSERLKVAPGE-QTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQS--QRVGSSPITTRQLESLIRLTEARARLELREEATREDAEDIIEIMKHSMLGTYSDEFGNLDFERSQHGSG--MSNRSTAKRFISALNSIAERTYNNIFQYHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQLQTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJA3-1", "uniprot_id": "MCM8_HUMAN", "id": "Q9UJA3-1", "name": "DNA helicase MCM8", "aln": "----------MNGEYRGRGFGRGRFQSWKRGRGGG---NFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQSTLDRFIP------------------------YKGWKLYFS-EVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLT-KDLERHAAELQAQEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPVPVCRGR-SFTALRSSPLTVTMDWQSIKIQELMSDDQREAGR-IPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSE-----------------------KPLSERLKVVPGE-TIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQS--QRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSG--MSNRSTAKRFISALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF30-1", "uniprot_id": "MCMR_DROME", "id": "Q9VF30-1", "name": "DNA replication licensing factor REC", "aln": "MNPTLSRGGAPSRFVRGRGRGGGAYRPYFYFRRNGRVIPAGGNRQPNQGEPGAPDAPSVPPATRQPRGWSRTAGKRGRNAHLDCSFLRPENYAAPEDGLQVQSIAVDNPRAYSGWRLYFLREKYEEGNELATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGTFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDVELRHDLVDAVRVGQEVVVTGILKLQELGDDTTTGDTSNQMQPYLKAVSIRDASSIKR-------------EFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETEAIN---------VLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRNKRVLQAGSLMMASGGGHCTLDDVDKLASKQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSE-RDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSSQIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESITQTSLKEGSSRQGTRGGGGAGGGAGKSAQLRNFLELTKRRSAALGRRIFEFDELKEIGTRAGILTG-FSQLVEMANLGGYLLMKGANMYEVVPD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **** * * :: : * .* .*. : . . .:.. .: : .: :: ** : *.**:*** * *.:.. : :* *.* :: *: . :* *. :* : : :.. ::.:: *.: :*: * :**. :.**:* *:. ::*: : : . : . .* :*:** :: *: ::.: . .. :::** * .*.: . * ** *: * :: . * :* . * .* .*..***** * * *:::* : :: :* :: ** *****: *: *.:***:*:.: :.: . : . : *::* *: ::.. * *** :** ** *:** * :**:*:*:.* ::**** **. *:*:**. :: * :*:*****:**:::**:..::* **.:*.*: : *. : :: . . . .. :: .. * * :*:.**:..:: .**:.::.:.:.*. **...*:**:.*:**.*** *:*::.: : :*:::..:** .*.**:****.*.* :* *: ** *::** :: *: : .: *:: :. *.:**:* * * * :* *::*::.**** : * *. :*:..: ::***: .. :. ** * : ** ::*:*::*****:* . .: :...*:: ::. *: * .* .. : *. *:* .: : :.*:. : : ..**::.:*::*... .* .. *.::: * **** **.::*:: . ", "identical_positions": 222, "similar_positions": 313, "identity": "24.42%" }, { "cls_id": "homologset.agr.FB:FBgn0003231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08623-1", "uniprot_id": "SQSTM_RAT", "id": "O08623-1", "name": "Sequestosome-1", "aln": "MASLTVKAYLLGKEEAAREIRRFSFCFSPEP--EAEAAAGPGPCERLLSRVAVLFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRREHRPPCAQEA-RSMVHPNVICDGCN-GPVVGTRYKCSVCPDYDLCSVCEGKGLHREHSKLIFPNPFG--HLSDSFSHS---RWLRKLKHGHFGWPGWEMGPPG----------------------------------------NWSPRPPRAGDGRPCP-----------TAESASAPSEDPNVN-------------------------FLKNVGESVAAALSPLGIEVD----------IDVEHGGKRSRLTPTSAE---------------SSSTGTEDKSGTQPSSCSSEVSKPDGAGEGPAQSLTEQMKKIALESVGQ----------------------PEELMESDNCSGGDDDWTHLSSK----------------------------EVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPP---EADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64337-1", "uniprot_id": "SQSTM_MOUSE", "id": "Q64337-1", "name": "Sequestosome-1", "aln": "MASFTVKAYLLGKEEATREIRRFSFCFSPEPEAEAQAAAGPGPCERLLSRVAVLFPTLRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRREHRPPCAQEAPRNMVHPNVICDGCN-GPVVGTRYKCSVCPDYDLCSVCEGKGLHREHSKLIFPNPFG--HLSDSFSHS---RWLRKLKHGHFGWPGWEMGPPG----------------------------------------NWSPRPPRAGDGRPCP-----------TAESASAPPEDPNVN-------------------------FLKNVGESVAAALSPLGIEVD----------IDVEHGGKRSRLTPTTPE---------------SSSTGTEDKSNTQPSSCSSEVSKPDGAGEGPAQSLTEQMKKIALESVGQ----------------------PEEQMESGNCSGGDDDWTHLSSK----------------------------EVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPP---EADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13501-1", "uniprot_id": "SQSTM_HUMAN", "id": "Q13501-1", "name": "Sequestosome-1", "aln": "MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCN-GPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFG--HLSEGFSHS---RWLRKVKHGHFGWPGWEMGPPG----------------------------------------NWSPRPPRAGEARPGP-----------TAESASGPSEDPSVN-------------------------FLKNVGESVAAALSPLGIEVD----------IDVEHGGKRSRLTPVSPE---------------SSST--EEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGR----------------------PEEQMESDNCSGGDDDWTHLSSK----------------------------EVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPP---EADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14199-1", "uniprot_id": "REF2P_DROME", "id": "P14199-1", "name": "Protein ref(2)P", "aln": "MPEKLLKITYQG-AGPQKKINAYLRMPSQNYTILRREIELYLFQERQLPKCDVRTFWIDADKDEIEIVNQNDYEIFLAKCESNMHVQVAPLAPVEEPKATKQEGSSANAEAPSVDDPSNFTIHDAVECDGCGLAPLIGFRYKCVQCSNYDLCQKCELAHKHPEHLMLRMPTNNGPGMVDAWFTGPGLGRRSGRRSRGHCPFQETNQADPAGEPARDSRRERRQARRHAGVLTQFVEMMTNLPLNTTTATAPAEPQKPKAAEQTESPPQAEPTVTAEKAAESEAKPTEPKKVNTDQSVPRTEDPVTTPRSTQPTTPVINLDNISQIVPPEYMSAGIEILNNFSEMFSKIIDTTEGGDSGIFAPSTTPSAENKKPEEQGQSSGQSGASSANQSAVPSAAPSANQSNVPSANQSATPSISGSIPDAQLETEPLNPKPSETTTETEQERRRSDSLDPEWQLIDNAYSANNSNLINLDTTNPTAAPQEPVRDFGQLGELLRQHMNEEARVEQASANTQTAQVDTVSTSTSTTSVTTNSVGTSPAAPDDKRTVPVYHTDESINKSIHAMMAMGFSNEGAWLTQLLESVQGNISAALDVMNVSQNRN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. :* * . ::*. : * : . ** *.: . : .. : . :::. : ::. *. . : . .::: . : ..*..::. . :* * ****. .*::* **** *.:****. ** * * * :*. * :. *: . * : .:** : : . *. .*: *:*.: * :*** : *.* .** *.*:.: *.. . ***: **. .**. . ::* :. .*.: ::* .:: .:: *: . :..: *:: .: . **: ** : .. *..:.: :*.:. .*: ::.: *: *: . .:* . ...* . ** : . .:* : :*: *::****:**.***:**:: : :*.****.:: *:: ", "identical_positions": 98, "similar_positions": 163, "identity": "16.28%" }, { "cls_id": "homologset.agr.FB:FBgn0003248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R456-1", "uniprot_id": "OPN4_RAT", "id": "Q8R456-1", "name": "Melanopsin", "aln": "MNSPSESRVPSSLTQD-PSFTASPALLQGIWNSTQN-ISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRAC-EGCGESPLR-RRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKT-----------KRHLPSLDR-----RM-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ9-1", "uniprot_id": "OPN4_MOUSE", "id": "Q9QXZ9-1", "name": "Melanopsin", "aln": "MDSPSGPRVLSSLTQD-PSFTTSPA-LQGIWNGTQN-VSVRAQLLSVSPTTSAHQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRAC-EGCGESPLRQRRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGRKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSQNLEDGELKASSSPQVQRSKTPKVPGPSTCRPMKGQGARPSSLRGDQKGRLAVCTGLSECPHPHTSQFPLAFLEDDVTLRHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHM6-1", "uniprot_id": "OPN4_HUMAN", "id": "Q9UHM6-1", "name": "Melanopsin", "aln": "MNPPSGPRVPPSPTQE-PSCMATPA-PPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRAL-QTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKT----------KGLIPSQDP-----RM-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08099-1", "uniprot_id": "OPS2_DROME", "id": "P08099-1", "name": "Opsin Rh2", "aln": "MERSHLPETPFDLAHSGPRFQAQSS-------------GNGSVLDNVLPDMAHLVNPYWSRFAPMDP--MMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIKT-SIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKIDG-LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCP-----MCVFGNTDEPKPDAPASDTETTSEADSKA----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . ... . ::. * : .: . * .: * . . * :..:* ** . * : : . ** .*:* * .:.******::::***.*** * :*:**:: . *: *::* *.:** **::** *: :: **:*** **.: : * : : :* :*: *: *:: *::********* **:** **:: *:* : **:: **::* :.* **: *: :* : . : .:* *:**: * .* *:.::*:** .:. ..: *** : *.:**:**::***:*.*:***** .: :: * : * . ..* . ::. .* :. *. ", "identical_positions": 114, "similar_positions": 122, "identity": "21.63%" }, { "cls_id": "homologset.agr.FB:FBgn0003249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R456-1", "uniprot_id": "OPN4_RAT", "id": "Q8R456-1", "name": "Melanopsin", "aln": "-MN--SPSESRVPSSLTQDPSFTASPALLQGIWNSTQN-ISVRVQLLSVSPTTP--GLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGES--PLR-RRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQ--RSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQES--------LGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAP----------------------SSPQEQKSKTPKT-----------KRHLPSLDR--------------------------------RM------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ9-1", "uniprot_id": "OPN4_MOUSE", "id": "Q9QXZ9-1", "name": "Melanopsin", "aln": "-MD--SPSGPRVLSSLTQDPSFTTSPA-LQGIWNGTQN-VSVRAQLLSVSPTTS--AHQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGES--PLRQRRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSGQ--RSHPSLSYRSTHRSTLSSQSSDLSWISGRKRQES--------LGSESEVGWTDTETTAAWGAAQQASGQSFCSQNLEDGELKAS----------------------SSPQVQRSKTPKVPGPSTCRPMKGQGARPSSLRG---------------------------DQKGRLAVCTGLSECPHPHTSQFPLAFLEDDVTLRHL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHM6-1", "uniprot_id": "OPN4_HUMAN", "id": "Q9UHM6-1", "name": "Melanopsin", "aln": "-MN--PPSGPRVPPSPTQEPSCMATPA-PPSWWDSSQSSISSLGRLPSISPTAP--GTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGAC--KGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRR--HSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQES--------LGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAP----------------------PRPQGHEAETPGKT----------KGLIPSQDP--------------------------------RM------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPS6-1", "uniprot_id": "OPN4L_DANRE", "id": "Q1JPS6-1", "name": "Melanopsin-like", "aln": "-MS--HHSSWRGHHCAPGDINCTAGFKESLGSRN------YKLLHVPVHGPTHS---HHHDPPHPFPTVDVPDHAHYIIGSVILIVGITGVIGNALVVYVFCRSRTLRTAGNMFIVNLAVADFLMSVTQSPVFFAASLHRRWVFGERPCELYAFCGALFGICSMMTLTAIAADRCLAITQPLALVSRVSRRKAGAVLVVVWLYSLGWSLPPFFG-WSAYVPEGLQTSCSWDYMTFTPSVRAYTILLFVFVFFIPLGIIGSCYFAIFQTIRAAGKEIRELDCG----ETHKVYER--MQNEWKMAKVALVVIVLFIISWSPYSVVALTATAGYSHFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRVAIARYIPVLRPILRVKEKDLRSSFSSGSVSSRRPTLTSQCSLGVSMGNAARANGRWGKTRLSSASDSDSCWTESEADGSSVSSLTFGRRVSTEISTDTVILS------------------------SGSSVSNASGQ---KSER----AHKVISVPVPS---------------------------------ITFETDAADGES---LSDGKALLGGN-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2KNE5-1", "uniprot_id": "OPN4A_DANRE", "id": "Q2KNE5-1", "name": "Melanopsin-A", "aln": "MMSGAAHSVRKGISCPTQDPNCTR-IVESLSAWNDSVMSAYRLVDLPPTTTTTTSVAMVEESVYPFPTVDVPDHAHYTIGAVILTVGITGMLGNFLVIYAFSRSRTLRTPANLFIINLAITDFLMCATQAPIFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLMVIAVDRYFVITRPLASIGVLSQKRALLILLVAWVYSLGWSLPPFFG-WSAYVPEGLLTSCTWDYMTFTPSVRAYTMLLFIFVFFIPLIVIIYCYFFIFRSIRTTNEAVGKINGDN-KRDSMKRFQR--LKNEWKMAKIALIVILMYVISWSPYSTVALTAFAGYSDFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRLAIAKYIPCLRLLLCVPKRDLHS-FHSSLMSTRRSTVTSQSSD---MSGRFRRTS-TGKSRLSSASDSESGWTDTEADLSSMSSRPASRQVSCDISKDTAEMPDFKPCNSSSFKSKLKSHDSGIFEKSSSDVDDVSVAGIIQPDRTLTNAGDITDVPISRGAIGRIPSIVITSESSSLLPSVRPTYRISRSNVSTVGTNPARRDSRGGVQQGAAHLSNAAETPESGHIDNHRPQYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04950-1", "uniprot_id": "OPS3_DROME", "id": "P04950-1", "name": "Opsin Rh3", "aln": "MESGNVSSSLFGNVSTALRPEARLSAETRLLGWNVPPE---ELRHIPEHWLTYP---------------EPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMM-MVKTPIFIYNSFHQGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPME--GKMTHGKAIAMIIFIYMYATPWVVACYTETWGRFVPEGYLTSCTFDYLTDNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLALNEKAPES-------SAVASTSTTQEPQQTTAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . . : : * . : *: :* :*:: : . : .::** *::.*. : ***..*::::***. **:* .::*:*: *::: : :*. *:::.: *: ** : * ** ** .**:*: . :: :: ::: ::*: * :. : *. :**** ***::**:: . .* :. : * *. * :* * *. : . :: * ::** : : .::. **:**..::* . * .*** . :** .* * :*::***:**:** : : * * . . *: . ..: : ", "identical_positions": 81, "similar_positions": 118, "identity": "13.43%" }, { "cls_id": "homologset.agr.FB:FBgn0003250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R456-1", "uniprot_id": "OPN4_RAT", "id": "Q8R456-1", "name": "Melanopsin", "aln": "-MN--SPSESRVPSSLTQDPSFTASPALLQGIWNSTQN-ISVRVQLLSVSPTTP--GLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGES--PLR-RRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQ--RSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQES--------LGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAP----------------------SSPQEQKSKTPKT-----------KRHLPSLDR--------------------------------RM------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ9-1", "uniprot_id": "OPN4_MOUSE", "id": "Q9QXZ9-1", "name": "Melanopsin", "aln": "-MD--SPSGPRVLSSLTQDPSFTTSPA-LQGIWNGTQN-VSVRAQLLSVSPTTS--AHQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGES--PLRQRRQWQR--LQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSGQ--RSHPSLSYRSTHRSTLSSQSSDLSWISGRKRQES--------LGSESEVGWTDTETTAAWGAAQQASGQSFCSQNLEDGELKAS----------------------SSPQVQRSKTPKVPGPSTCRPMKGQGARPSSLRG---------------------------DQKGRLAVCTGLSECPHPHTSQFPLAFLEDDVTLRHL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHM6-1", "uniprot_id": "OPN4_HUMAN", "id": "Q9UHM6-1", "name": "Melanopsin", "aln": "-MN--PPSGPRVPPSPTQEPSCMATPA-PPSWWDSSQSSISSLGRLPSISPTAP--GTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGAC--KGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRR--HSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQES--------LGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAP----------------------PRPQGHEAETPGKT----------KGLIPSQDP--------------------------------RM------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPS6-1", "uniprot_id": "OPN4L_DANRE", "id": "Q1JPS6-1", "name": "Melanopsin-like", "aln": "-MS--HHSSWRGHHCAPGDINCTAGFKESLGSRN------YKLLHVPVHGPTHS---HHHDPPHPFPTVDVPDHAHYIIGSVILIVGITGVIGNALVVYVFCRSRTLRTAGNMFIVNLAVADFLMSVTQSPVFFAASLHRRWVFGERPCELYAFCGALFGICSMMTLTAIAADRCLAITQPLALVSRVSRRKAGAVLVVVWLYSLGWSLPPFFG-WSAYVPEGLQTSCSWDYMTFTPSVRAYTILLFVFVFFIPLGIIGSCYFAIFQTIRAAGKEIRELDCG----ETHKVYER--MQNEWKMAKVALVVIVLFIISWSPYSVVALTATAGYSHFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRVAIARYIPVLRPILRVKEKDLRSSFSSGSVSSRRPTLTSQCSLGVSMGNAARANGRWGKTRLSSASDSDSCWTESEADGSSVSSLTFGRRVSTEISTDTVILS------------------------SGSSVSNASGQ---KSER----AHKVISVPVPS---------------------------------ITFETDAADGES---LSDGKALLGGN-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2KNE5-1", "uniprot_id": "OPN4A_DANRE", "id": "Q2KNE5-1", "name": "Melanopsin-A", "aln": "MMSGAAHSVRKGISCPTQDPNCTR-IVESLSAWNDSVMSAYRLVDLPPTTTTTTSVAMVEESVYPFPTVDVPDHAHYTIGAVILTVGITGMLGNFLVIYAFSRSRTLRTPANLFIINLAITDFLMCATQAPIFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLMVIAVDRYFVITRPLASIGVLSQKRALLILLVAWVYSLGWSLPPFFG-WSAYVPEGLLTSCTWDYMTFTPSVRAYTMLLFIFVFFIPLIVIIYCYFFIFRSIRTTNEAVGKINGDN-KRDSMKRFQR--LKNEWKMAKIALIVILMYVISWSPYSTVALTAFAGYSDFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRLAIAKYIPCLRLLLCVPKRDLHS-FHSSLMSTRRSTVTSQSSD---MSGRFRRTS-TGKSRLSSASDSESGWTDTEADLSSMSSRPASRQVSCDISKDTAEMPDFKPCNSSSFKSKLKSHDSGIFEKSSSDVDDVSVAGIIQPDRTLTNAGDITDVPISRGAIGRIPSIVITSESSSLLPSVRPTYRISRSNVSTVGTNPARRDSRGGVQQGAAHLSNAAETPESGHIDNHRPQYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08255-1", "uniprot_id": "OPS4_DROME", "id": "P08255-1", "name": "Opsin Rh4", "aln": "-----------------MEPLCNASEPPLRPEARSSGN-----GDLQFLGWNVPPDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL-KAPIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRN--MTFTKAVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGVNE-----------KSGEISSAQSTTTQEQQQTTAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . :. :: * ** :* . : : :. :** *:: *. .: ***..*::::***: *::*. ::*:*: *::: : :*: *:::* *: ** : :* .*. ** .**:*: : :: : : *:*. * : *: *. :**** ***::**:: . .* :. : * *. * :* * *. : . :: * ::** : : .::.:**:**..::* . * .*** . :** .* * :*::***:**:** : : * * . *: :.* :.. . ", "identical_positions": 82, "similar_positions": 113, "identity": "13.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2H4-1", "uniprot_id": "LGR4_RAT", "id": "Q9Z2H4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-----------------------------------------------------------------------------------------------------------------------MPGPLRLLCFFALGLLGSAGPSGAAPPLCAAPCSCDGDR----RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKSFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLRTVPSEAIHGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHCFDGLDNLETLDLNYNNLDEFPQAIKALPSLKELGFHSNSISVIPDGAFGGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASLVQWFPNLTGTVHLESLTLTGTKISSIPDDLCQNQKMLRTLDLSYNNIRDLPSFNGCRALEEISLQRNQISLIK------------------------ENTFQGLTSLRILDLSRNLIREIHSGAFAKLGTITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKDALAARDFANLRSLSVPYAYQCCAFWGCDSYANLN----TEDNSPQEHSVTKEKG-----------ATDAANVTS--------------------------------------------------------TAENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALLFNLLVILTVFAS-CSSLPASKLFIGLISVSNLLMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGSLAVFSSESAVFLLTLAAVERSVFAKDLMKHG--------KSSHLRQFQVAALLALLGAAVAGCFPLFHGGQYSASPLCLP--FPTGETPSLGFTVTLVLLNSLAFLLMAIIYTKLYCNLEKEDLSENSQSSVIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRR-----------------------------------------------------------------------------VTRKHGSVSVSISSQ----GGCGEQD----FYYDCGMYSHLQGN-LTVCDCCESFLLTKPVS--------------------------------------------CKHLIKSHSCPVLT--AASCQRPEAYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFPLVRYAYNLQRVRD-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARI4-1", "uniprot_id": "LGR4_MOUSE", "id": "A2ARI4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-----------------------------------------------------------------------------------------------------------------------MPGPLRLLCFFALGLLGSAGPSGAAPPLCAAPCSCDGDR----RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNILTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHCFDGLDNLETLDLNYNNLDEFPQAIKALPSLKELGFHSNSISVIPDGAFAGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASLVQWFPNLAGTVHLESLTLTGTKISSIPDDLCQNQKMLRTLDLSYNDIRDLPSFNGCRALEEISLQRNQISLIK------------------------ETTFQGLTSLRILDLSRNLIREIHSGAFAKLGTITNLDVSFNELTSFPTEGLNGLNQLKLVGNFQLKDALAARDFANLRSLSVPYAYQCCAFWGCDSYANLN----TEDNSPQDHSVTKEKG-----------ATDAANATS--------------------------------------------------------TAESEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALLFNLLVILTVFAS-CSSLPASKLFIGLISVSNLLMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGSLAVFSSESAVFLLTLAAVERSVFAKDVMKNG--------KSSHLRQFQVAALVALLGAAIAGCFPLFHGGQYSASPLCLP--FPTGETPSLGFTVTLVLLNSLAFLLMAIIYTKLYCNLEKEDPSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKDDWKLLKRR-----------------------------------------------------------------------------VTRKHGSVSVSISSQ----GGCGEQD----FYYDCGMYSHLQGN-LTVCDCCESFLLTKPVS--------------------------------------------CKHLIKSHSCPVLT--VASCQRPEAYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFPLVRYAYNLPRVRD-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXB1-1", "uniprot_id": "LGR4_HUMAN", "id": "Q9BXB1-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-----------------------------------------------------------------------------------------------------------------------MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDR----RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQIYQIK------------------------EGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYANLN----TEDNSLQDHSVAQEKG-----------TADAANVTS--------------------------------------------------------TLENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALFFNLLVILTTFAS-CTSLPSSKLFIGLISVSNLFMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLATVERSLSAKDIMKNG--------KSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLP--FPTGETPSLGFTVTLVLLNSLAFLLMAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRR-----------------------------------------------------------------------------VTKKSGSVSVSISSQ----GGCLEQD----FYYDCGMYSHLQGN-LTVCDCCESFLLTKPVS--------------------------------------------CKHLIKSHSCPALA--VASCQRPEGYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFPLVRYAYNLPRVKD-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE13-1", "uniprot_id": "LGR4_DANRE", "id": "E7FE13-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "--------------------------------------------------------------------------------------------------------------------MALLAVRMLVLGLCVGGQAAAAGEGQSTPATCSPLCRCDEDG----GADCSGRGLTSVPTGLSAFTYYLDISMNNITELPANVFRNLPYLEELRLAGNDLAFIHPEALSGLHQLKVLMLQNNQLKTVPSAALKNLNALQSLRLDANHITSVPEDSFEGLQQLRHLWLDDNSLTEVPISPLQHQSNLQALTLALNRITHIPDNAFANLSSLVVLHLHNNRIQEIGKNCFNGLDNLETLDLNFNNLKIFPEAIQMLPKLKELGFHSNNIASIPEGAFCRNSLLRTIHLFDNPLSFVGTTAFQNLSDLHSLMLRGASMMQDFPSLTGTINLESLTLTGTKIRSIPADLCEDLTVLRTVDLSYNDIEDLPSFQGCVRLQDINLQHNQIKQID------------------------RGTFQGMTSLRVLDLSRNQIKFIHRDAFLSLSALTNLDLSLNSLASVPTAGLSALNQLKLTGNMELRNGLMSKTLPKLRSITVPYAYQCCAFVAYDSAVNPA----EDD--------------------------ERRNAFG--------------------------------------------------------GEEDMERIPMVMHCSPLPGAFKPCEHLLGSWMIRLTVWFICLVALLFNCLVLAATFSPRTSSLSPSRFLVALLASANLLTGVYVAALTLLDTVTWGSFAEYGVWWETGAGCQVVGFLAVFSSEWAVLLLALAAVERCLAVRALMGKAGALRSRGERRERRRRFAIAALLLGLVSVAAACLSLYHG-SAMGSPLCLP--FSEGSSPGLGFTVALVLMNTLAYLLSAVVYTRLYCRLGRAQLADPEQAGSVRHIAWLIFTNCIFFCPVAAFSFAPLLAGTSNAVGGPEMAKSVTLIFFPLSACLNPVLYVCFSPSFRYDWLHLRGRG----------------------------------------------------------------------------RTGGCGRLVAKTVTKGTVAGGSPVSDDGEGLSSDCGMYTKLHGDSRGMCEHCDAALHIRTSSS-----------------------------------SGSSSSSACRHLVKSHSCPALMGNVPQCLSSEGYWPDTGTLSAQSEYGDEGDSFVSDSSEQVQACGRACFCQSRGLPLVHYSYNIPRMTD-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4AC13-1", "uniprot_id": "LGR5_RAT", "id": "D4AC13-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 5", "aln": "-----------------------------------------------------------------------------------------------------------------MDTS-RVRMLLSLLALLQLVAAGSPPRPDTMPRGCPSYCHCELDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLPASLLHRLRFLEELRLAGNALTHIPKGAFAGLHSLKVLMLQNNQLRQVPEEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTDVPVQAFRSLSALQAMTLALNKIHHIADHAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIKTLSNLKELGFHSNNIRSIPERAFVGNPSLITIHFYDNPIQFVGISAFQHLPELRTLTLNGASQITEFPDLTGTATLESLTLTGAKISSLPQTVCDQLPNLQVLDLSYNLLEDLPSLSGCQKLQKIDLRHNEIYEIK------------------------GGTFQQLFNLRSLNLARNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPVTGLHGLTHLKLTGNRALQSLIPSANFPELKIIEMPYAYQCCAFGGCENVYKIPNQWNKDDSS-SVDDLRKKDAGLFQVQDE----RDLEDFLL--------------------------------------------------------DFEEDLKVLHSVQCSPPPGPFKPCEHLFGSWLIRIGVWTTAVLALSCNALVAFTVFR-TPLYISSIKLLIGVIAVVDILMGVSSAILAVVDTFTFGSFAQHGAWWEGGIGCQIVGFLSIFASESSVFLLTLAALERGFSVKCSSKFE--------MKAPLSSLKAIILLCVLLALTIATVPLLGGSEYNASPLCLP--LPFGEPSTTGYMVALVLLNSLCFLIMTIAYTRLYCSLEKGELENLWDCSMVKHTALLLFTNCILYCPVAFLSFSSLLNLTF---ISPEVIKFILLVIVPLPACLNPLLYIVFNPHFKEDMGSLGKQT----------------------------------------------------------------------------RFWTRAKHPSLLSINSD------------------DVEKRSCDSTQALVSFTHASIAYDLPSD-------------------------------------------------SGSSPAYP------MTESCHLS-----------------------------------------SVAFVPCL------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1P4-1", "uniprot_id": "LGR5_MOUSE", "id": "Q9Z1P4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 5", "aln": "-----------------------------------------------------------------------------------------------------------------MDTS-CVHMLLSLLALLQLVAAGSSPGPDAIPRGCPSHCHCELDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLPASLLHRLCFLEELRLAGNALTHIPKGAFTGLHSLKVLMLQNNQLRQVPEEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTDVPVQAFRSLSALQAMTLALNKIHHIADYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIKTLSNLKELGFHSNNIRSIPERAFVGNPSLITIHFYDNPIQFVGVSAFQHLPELRTLTLNGASHITEFPHLTGTATLESLTLTGAKISSLPQAVCDQLPNLQVLDLSYNLLEDLPSLSGCQKLQKIDLRHNEIYEIK------------------------GSTFQQLFNLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPVTGLHGLTHLKLTGNRALQSLIPSANFPELKIIEMPSAYQCCAFGGCENVYKISNQWNKDDGN-SVDDLHKKDAGLFQVQDE----RDLEDFLL--------------------------------------------------------DFEEDLKALHSVQCSPSPGPFKPCEHLFGSWLIRIGVWTTAVLALSCNALVALTVFR-TPLYISSIKLLIGVIAVVDILMGVSSAVLAAVDAFTFGRFAQHGAWWEDGIGCQIVGFLSIFASESSIFLLTLAALERGFSVKCSSKFE--------VKAPLFSLRAIVLLCVLLALTIATIPLLGGSKYNASPLCLP--LPFGEPSTTGYMVALVLLNSLCFLIMTIAYTKLYCSLEKGELENLWDCSMVKHIALLLFANCILYCPVAFLSFSSLLNLTF---ISPDVIKFILLVIVPLPSCLNPLLYIVFNPHFKEDMGSLGKHT----------------------------------------------------------------------------RFWMRSKHASLLSINSD------------------DVEKRSCESTQALVSFTHASIAYDLPST-------------------------------------------------SGASPAYP------MTESCHLS-----------------------------------------SVAFVPCL------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75473-1", "uniprot_id": "LGR5_HUMAN", "id": "O75473-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 5", "aln": "-----------------------------------------------------------------------------------------------------------------MDTS-RLGVLLSLPVLLQLATGGSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIK------------------------VDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNHALQSLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQWNKGDNS-SMDDLHKKDAGMFQAQDE----RDLEDFLL--------------------------------------------------------DFEEDLKALHSVQCSPSPGPFKPCEHLLDGWLIRIGVWTIAVLALTCNALVTSTVFR-SPLYISPIKLLIGVIAAVNMLTGVSSAVLAGVDAFTFGSFARHGAWWENGVGCHVIGFLSIFASESSVFLLTLAALERGFSVKYSAKFE--------TKAPFSSLKVIILLCALLALTMAAVPLLGGSKYGASPLCLP--LPFGEPSTMGYMVALILLNSLCFLMMTIAYTKLYCNLDKGDLENIWDCSMVKHIALLLFTNCILNCPVAFLSFSSLINLTF---ISPEVIKFILLVVVPLPACLNPLLYILFNPHFKEDLVSLRKQT----------------------------------------------------------------------------YVWTRSKHPSLMSINSD------------------DVEKQSCDSTQALVTFTSSSITYDLPPS-------------------------------------------------SVPSPAYP------VTESCHLS-----------------------------------------SVAFVPCL------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZJU9-1", "uniprot_id": "D3ZJU9_RAT", "id": "D3ZJU9-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MHSSPLLLALCLCVVLCALARAGSDPQPGPGRPACPAPCHCQEDG-IMLSADCSELGLSEVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPRQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSLNGATDIQEFPDLKGTTSLEILTLTRAGIRLLPAGMCQQLPRLRILELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIG------------------------ADTFSQLSSLQALDLSWNAIRAIHPEAFSTLRSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCAYGLCANFFKTSGQWQAEDFHAEEEEAPKRPLGLLAGQAENHYDLDLDELQM--------------------------------------------------------ETEDS-KPHPSVQCSPVPGPFKPCEHLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPSPLSPVKLVVGAIAGANALTGISCGLLASVDALTFGQFAEYGARWETGLGCQATGFLAVLGSEASVLLLTLAAVQCSVSVTCVRAYG--------KAPSPGSVRAGALGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGRPAALGFAVALVMMNSLCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFP---VTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFREDLR----------------------------------------------------------------------------------RLWPSPRSPGPLAYTAAG-----------------ELEKSSCDSTQALVAFSDVDLILEASEAGQP--------------------------------PGLETYGFPSVTLISRHQPGAT------RLEGNHFVEPDGTKLGNPQPPMNEELLLRAEGATLADC--SAGGALWPSGPLFASHL------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UVD5-1", "uniprot_id": "LGR6_MOUSE", "id": "Q3UVD5-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 6", "aln": "-----------------------------------------------------------------------------------------------------------------MHSPPGLLALWLCAVLCASARAGSDPQPGPGRPACPAPCHCQEDG-IMLSADCSELGLSVVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPLAIRTLGRLQELGFHNNNIKAIPEKAFMGSPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSLNGATDIQEFPDLKGTTSLEILTLTRAGIRLLPPGVCQQLPRLRILELSHNQIEELPSLHRCQKLEEIGLRHNRIKEIG------------------------ADTFSQLGSLQALDLSWNAIRAIHPEAFSTLRSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCAYGICASFFKTSGQWQAEDFHPEEEEAPKRPLGLLAGQAENHYDLDLDELQM--------------------------------------------------------GTEDS-KPHPSVQCSPVPGPFKPCEHLFESWGIRLAVWAIVLLSVLCNGLVLLTVFASGPSPLSPVKLVVGAMAGANALSGISCGLLASVDALTYGQFAEYGARWESGLGCQATGFLAVLGSEASVLLLTLAAVQCSISVTCVRAYG--------KAPSPGSVRAGALGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGRPAALGFAVALVMMNSLCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFP---VTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLR----------------------------------------------------------------------------------RLWPSPRSPGPLAYAAAG-----------------ELEKSSCDSTQALVAFSDVDLILEASEAGQP--------------------------------PGLETYGFPSVTLISRHQPGAT------RLEGNHFVESDGTKFGNPQPPMKGELLLKAEGATLAGCGSSVGGALWPSGSLFASHL------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBX8-3", "uniprot_id": "LGR6_HUMAN", "id": "Q9HBX8-3", "name": "Leucine-rich repeat-containing G protein-coupled receptor 6", "aln": "-----------------------------------------------------------------------------------------------------------------MPSPPGLRALWLCAALCASRRAGGAPQPGPGPTACPAPCHCQEDG-IMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIG------------------------ADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRPLGLLARQAENHYDQDLDELQL--------------------------------------------------------EMEDS-KPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVVGAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYG--------KSPSLGSVRAGVLGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFP---VTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLR----------------------------------------------------------------------------------RLRPRAGDSGPLAYAAAG-----------------ELEKSSCDSTQALVAFSDVDLILEASEAGRP--------------------------------PGLETYGFPSVTLISCQQPGAP------RLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGLAFASHV------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KTA0-1", "uniprot_id": "Q7KTA0_DROME", "id": "Q7KTA0-1", "name": "", "aln": "MAARCRWSWRLALCPLLLQLLLQLLLLPPSAMGHDETKENPAPDMQNSQEQEPYVHLQHLQQQQQQNPQTVQQLSQITVNRTSKSASVTPTGIRENVMLPSADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSL-EVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPRS--MQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLHLKTFNNPKLREFPPPDTFPRIQTLILSYAYHCCAFLPLVAMSSQKKTSQVQEAVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGASMHDPWETAINFNEEQLQTQTGGQIATSYMEEYFEEHDVSGPATGYGFGTGLFSGMSTEDFQPGSVQCLPMPGPFLPCADLFDWWTLRCGVWVVFLLSLLGNGTVVFVLLCS-RSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLN--------KRLSLKQAGYIMSVGWVFALIMALMPLVGVSDYRKFAVCLPFETTTG-PASLTYVISLMFINGCAFLTLMGCYLKMYWAIRGSQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQL---ISLEQAKIFTVFVLPLNSCCNPFLYAIMTKQFKKDCVTLCKHFEESRVVGGGGPGGRGAVARTKRGDLPPPLLPAAAVAHPPGCRCLRMLPSEMPNWHKMEQTPSMWQRLRTFCCGENRRRRKQRRQPQQRRQRAYTAAAANPYQYQFAELRQQRQNRASSISSENFCSSRSSSWRHGPPSSAPVPPGNCSMPLKMLEPHAHPHGHGRRRHSAWLITRKTSQDSNLSSSRNDSSASATTASTSTFRLSRSSAGSSTPLPSIIAHNGKAQLDAVKPRLVRQEAVQEEEDSSPPRLGVRFLPTIPSAADSSVVMEDGDSANTGVASFLGMPLPGASSGFLIAPTTAATTSPPPVVLQPAKPPPDPNDAPL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * . .* *: :* .* . **:. **:::* . : **** *:.* : : *: ** .** * **. * :* :: * * **:*:.* : : .: * .** * *:.* : :* .: *:*:.*. * : * * * .:..*:** *:.*:* :. .:..* *:.*:*: * : :* .: * *:**.: .* : * : : . : :.: **:. :. **: :..*:.* : .. : ** * . ** *.* : * :* :* : *: ::*. * :. :*.: * *. :.* *.* * :*. : .*: *:* * * ** ** : .: .*:: * :. .* ** .* :** .* * . : .:: : :. **:**.: . : . . . ::* * .*.* ** *: * :* ** :::: * * . : : ::.: :: : : *: . *: :*: : * * .. *: . *: * *:::.** :: * : ::: : . ..* . .:*** . * .. : ::*:::* .:* * ::* : : :. :: * *:*:: : .*:* :*::.:: : * . :...** :* **.** :. *: * . . . . : : ", "identical_positions": 166, "similar_positions": 241, "identity": "12.06%" }, { "cls_id": "homologset.agr.FB:FBgn0003256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14681-1", "uniprot_id": "KSS1_YEAST", "id": "P14681-1", "name": "Mitogen-activated protein kinase KSS1", "aln": "------------------------------MARTITFDIPSQYKLVDLIGEGAYGTVCSAIHK--PSGIKVAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVG---FMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTP-SFEDFNQIKSKRAKEYIAN--LPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYPPLNLDDEFWKLDNKIMRPEEEEEVPIEMLKDMLYDELMKTME-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P16892-1", "uniprot_id": "FUS3_YEAST", "id": "P16892-1", "name": "Mitogen-activated protein kinase FUS3", "aln": "------------------------------MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHK--PTGEIVAIKKIE-PFDKPLFALRTLREIKILKHF-KHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQ-----MLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKS--LPMYPAAPLEKMFPR--VNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPS--FFEFD------HYKEALTTKDLKKLIWNEIFS----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P63085-1", "uniprot_id": "MK01_MOUSE", "id": "P63085-1", "name": "Mitogen-activated protein kinase 1", "aln": "-MAAAAAAG-------------------PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDN--LNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRF-RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQ-----HLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP-SQEDLNCIINLKARNYLLS--LPHKNKVPWNRLFPN--ADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEP------IAEAPFKFD------MELDDLPKEKLKELIFEETARFQPGYRS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63086-1", "uniprot_id": "MK01_RAT", "id": "P63086-1", "name": "Mitogen-activated protein kinase 1", "aln": "-MAAAAAAG-------------------PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDN--LNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRF-RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQ-----HLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP-SQEDLNCIINLKARNYLLS--LPHKNKVPWNRLFPN--ADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEP------IAEAPFKFD------MELDDLPKEKLKELIFEETARFQPGYRS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28482-1", "uniprot_id": "MK01_HUMAN", "id": "P28482-1", "name": "Mitogen-activated protein kinase 1", "aln": "-MAAAAAAGAG-----------------PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDN--VNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRF-RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQ-----HLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP-SQEDLNCIINLKARNYLLS--LPHKNKVPWNRLFPN--ADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEP------IAEAPFKFD------MELDDLPKEKLKELIFEETARFQPGYRS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63844-1", "uniprot_id": "MK03_MOUSE", "id": "Q63844-1", "name": "Mitogen-activated protein kinase 3", "aln": "MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDH--VRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRF-RHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQ-----QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP-SQEDLNCIINMKARNYLQS--LPSKTKVAWAKLFPK--SDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEP------VAEEPFTFD------MELDDLPKERLKELIFQETARFQPGAPEGP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21708-1", "uniprot_id": "MK03_RAT", "id": "P21708-1", "name": "Mitogen-activated protein kinase 3", "aln": "MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDH--VRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRF-RHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQ-----QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP-SQEDLNCIINMKARNYLQS--LPSKTKVAWAKLFPK--SDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEP------VAEEPFTFD------MELDDLPKERLKELIFQETARFQPGAPEAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27361-1", "uniprot_id": "MK03_HUMAN", "id": "P27361-1", "name": "Mitogen-activated protein kinase 3", "aln": "-MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDH--VRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRF-RHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQ-----QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP-SQEDLNCIINMKARNYLQS--LPSKTKVAWAKLFPK--SDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEP------VAEEPFTFA------MELDDLPKERLKELIFQETARFQPGVLEAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40417-3", "uniprot_id": "ERKA_DROME", "id": "P40417-3", "name": "Mitogen-activated protein kinase ERK-A", "aln": "-MEEFNSSGSVVNG----TGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDT--LTNQRVAIKKIS-PFEHQTYCQRTLREITILTRF-KHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQ-----RLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTG-------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSP-SRDDLECIINEKARNYLES--LPFKPNVPWAKLFPN--ADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEP------VAEVPFRIN------MENDDISRDALKSLIFEETLKFKERQPDNAP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41808-1", "uniprot_id": "SMK1_YEAST", "id": "P41808-1", "name": "Sporulation-specific mitogen-activated protein kinase SMK1", "aln": "-MNCTLTDNTRAIN----VASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTS-SPYDGLYCYQELIDYDLAKVIHSS----VQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQP--HITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTP-DKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPF--ASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEP-----VCLQGPFDFT------YESELNSMSKLRDYLVEEVKNFKTDLSSSSL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : :*:**** * *. :*:***. *.: *::**: :: * *:*:: : : : . :* : *:: ** ::: .. **: *: ** ** * .:* :*.::*:***:**.*:* . . **:******* :*:***********::*. *: ::*:*: ******: :*:* *:. .*: *: ::*:* . : : : . :* : . * . ::. . ::*: :* ::. :*: . :*: **:* .* *** : : : . . *:. : :* ", "identical_positions": 93, "similar_positions": 105, "identity": "22.46%" }, { "cls_id": "homologset.agr.FB:FBgn0003257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13439-1", "uniprot_id": "UMPS_MOUSE", "id": "P13439-1", "name": "Uridine 5'-monophosphate synthase", "aln": "-MEVASQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTAKNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHAVCTLSQMLEILQQQEKIDADMVGRVKRFI------QENVFSAANHNGLPPPEKKACKELSFGARAELPGTHPLASKLLRLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLD-VMEELTALAKRHEFLIFEDRKFADIGNTVKKQYESGTFKIASWADIVNAHVVPGSGVVKGLQE-VGLPLH---RACLLIAEMSSAGSLATGNYTKAAVGMAEE--HCEFVIGFISGSRVSMKP---EFLHLTPGVQLETGGDHLGQQYNSPQEVIGKRGSDVIIVGRGILA-AANRLEAAEMYRKAAWEAYLSRLAVQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2N2-1", "uniprot_id": "A0ABK0M2N2_RAT", "id": "A0ABK0M2N2-1", "name": "Uridine 5'-monophosphate synthase", "aln": "-MEVARQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTARNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHSVCTLSEMLEILEQQKKIDAEMVGRVKRFI------QENVFTAANHNGVPPPEKKACKELSFGARAELPGVHPLASKLLTLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLD-VMEELTTLAKRHEFLIFEDRKFADIGNTVKKQYESGIFKIASWADVVNAHVVPGSGVVKGLQE-VGLPLH---RACLLIAEMSSAGSLATGDYTKAAVGMAEE--HCEFVIGFISGSRVSMKP---EFLHLTPGVQLETGGDHLGQQYNSPQEVVGKRGSDVIIVGRGILA-AANRLEAAEMYRKAAWEAYLSFTAVNRHHDQGKSYKNSM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11172-1", "uniprot_id": "UMPS_HUMAN", "id": "P11172-1", "name": "Uridine 5'-monophosphate synthase", "aln": "-MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFI------QENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLD-VMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQE-VGLPLH---RGCLLIAEMSSTGSLATGDYTRAAVRMAEE--HSEFVVGFISGSRVSMKP---EFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIIS-AADRLEAAEMYRKAAWEAYLSRLGV--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P03962-1", "uniprot_id": "PYRF_YEAST", "id": "P03962-1", "name": "Orotidine 5'-phosphate decarboxylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKATYKER--------------------------AATHPS------------------------PVAAKLFNIMHEKQTNLCASLDVRTTKELLELVEALGPKICLLKTHVDILTDFSMEGTVKPLKALSAKYNFLLFEDRKFADIGNTVKLQYSAGVYRIAEWADITNAHGVVGPGIVSGLKQ-AAEEVTKEPRGLLMLAELSCKGSLATGEYTKGTVDIAKS--DKDFVIGFIAQRDMGGRDEGYDWLIMTPGVGLDDKGDALGQQYRTVDDVVS-TGSDIIIVGRGLFAKGRDAKVEGERYRKAGWEAYLRRCGQQN------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q01637-1", "uniprot_id": "UMPS_DROME", "id": "Q01637-1", "name": "Uridine 5'-monophosphate synthase", "aln": "MVAQNSDKMRALALKLFEINAFKFGDFKMKVGINSPVYFDLRVIVSYPDVMQTVSDLLVEHIKDKQLSAKHVCGVPYTALPLATIVSVQQGTPMLVRRKEAKAYGTKKLVEGIFNAGDTCLIVEDVVTSGSSILDTVRDLQGEGIVVTDAVVVVDREQGGVANIAKHGVRMHSLFTLSFLLNTLHEAGRIEKSTVEAVAKYIAAVQINSDGTFVGGDKGDVVRANDLQRTKLTYENRANLAKS-AVAKRLFNLIASKQTNLCLAADLTHADEILDVADKCGPYICLLKTHVDIVEDFSDK-FIADLQALAQRHNFLLMEDRKFADIGNTVSLQYGKGIYKISSWADLVTAHTLPGRSILQGLKAGLGEGGAGKERGVFLLAEMSASGNLIDAKYKENSNKIATEGADVDFVAGVVCQSSDAFAFP--GLLQLTPGVKIDEGVDQLGQQYQSPEHVVKERGADIGVVGRGILK-ASSPKQAAQTYRDRLWAAYQDRVAK--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. : . .:* :*: :: .*:**** : *: : *:*::.: ** **:*******: **: . : * :*: ::**::************. ** * ::*:.***:..** : * .::.**: . *. :::**:*. *.* ..*.. : :* . . :** *.:. . * :**** :: * *****.: :.*: *:*: :****:: . . .: **. * ** . ", "identical_positions": 85, "similar_positions": 88, "identity": "16.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17844-1", "uniprot_id": "DDX5_HUMAN", "id": "P17844-1", "name": "Probable ATP-dependent RNA helicase DDX5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGYSSD-RDRGRDRGFGAPRFGGSRA----------------------GPLSGKKFGNPGEKLVKKKW--NLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRG-HNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE--NKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSG-------RSRGRGG--------MKDDRRDRYSAGKRGG----FNTFRDRENYDRG-YSS-----LLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTS--FRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPAT-AAAPMIGYPMPTGYSQ------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61656-1", "uniprot_id": "DDX5_MOUSE", "id": "Q61656-1", "name": "Probable ATP-dependent RNA helicase DDX5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSYSSD-RDRGRDRGFGAPRFGGSRT----------------------GPLSGKKFGNPGEKLVKKKW--NLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRG-HNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE--NKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSG-------RSRGRGG--------MKDDRRDRYSAGKRGG----FNTFRDRENYDRG-YSN-----LLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTS--FRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPLP-QAAPMIGYPMPTGYSQ------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G4Y3-1", "uniprot_id": "A0A8I6G4Y3_RAT", "id": "A0A8I6G4Y3-1", "name": "Probable ATP-dependent RNA helicase DDX5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------GAPGVPREYKGRFRGRLFGAPRFGGSRT----------------------GPLSGKKFGNPGEKLVKKKW--NLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRG-HNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE--NKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSG-------RSRGRGG--------MKDDRRDRYSAGKRGG----FNTFRDRENYDRG-YSS-----LLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTS--FRTGNPTGTYQNGYDSTQQYGSNVANMHNGMNQQAYAYPATAAAAPMIGYPMPTGYSQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q501J6-1", "uniprot_id": "DDX17_MOUSE", "id": "Q501J6-1", "name": "Probable ATP-dependent RNA helicase DDX17", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGGGFGDRDRDRDRGG----FGARGG----------------------SGLPPKKFGNPGERLRKKKW--DLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE--NKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGG--GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSTSYRDRSETDRASYANGSGYGSPNSAFGAQAGQYTYAQGTYGAAAYGTSGYTAQEYAAGTYGASSTASAGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PT29-1", "uniprot_id": "E9PT29_RAT", "id": "E9PT29-1", "name": "RNA helicase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGGGFGDRDRDRDRGG----FGARGG----------------------SGLPPKKFGNPGERLRKKKW--DLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE--NKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSTSYRDRSETDRASYANGSGYGSPNSAFGAQAGQYTYAQGTYGAAAYGTSGYTAQEYAAGTYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92841-4", "uniprot_id": "DDX17_HUMAN", "id": "Q92841-4", "name": "Probable ATP-dependent RNA helicase DDX17", "aln": "------------------------------------------------------------------------------------MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGG----FGARGG----------------------GGLPPKKFGNPGERLRKKKW--DLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE--NKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGG--GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24783-1", "uniprot_id": "DBP2_YEAST", "id": "P24783-1", "name": "ATP-dependent RNA helicase DBP2", "aln": "--------------------------------------------------------------------------------------MTYGGRDQQYNKTNYKS------------------------------------------------------------RGGDFRGGRNSDRNSYNDRPQGGNYR-----------------------GGFGGRSNYNQPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMTISG-HDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNE--YKTLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPELLKYD-----------------------------------------------------------------------RRS---YGGGHPRYGGGRGGRGGYGRRGGYGGGRGG--YGGNRQRDGGWGNRGRSNY---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19109-1", "uniprot_id": "DDX17_DROME", "id": "P19109-1", "name": "ATP-dependent RNA helicase p62", "aln": "MLKLVQYIAPRVGGATPRPTACGWGNLLLISPRSGASSEKCITQRRHFLFSSASSSGTFASSSSLCTEQRQQFHGSRRNRETILFPSTYSSLQAQSQRAFRDSSKPDSDDYVDSIPKAEQRTRTRKSLFNDPDERTEEIKIEGVMAPHDRDFGHSGRGGRGGDRGGDDRRGGGGGGNRFGGGGGGGDYHGIRNGRVEKRRDDRGGGNRFGGGGGFGDRRGGGGGGSQDLPMRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQRYREEQEITVRG--QVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQPLQRGDGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFIRSFGVRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREANQEINPALENLA-----------------------------------------------------------------------RNSRYDGGGGRSRYGGGGGG-GRFGG-GGFKKGSLS--NGRGFGGGGGGGGEGRHSRFD-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * . : : . :: :*. *:**** ** .: : *: *..:*:*: * *:*: * .. :* *:. : : : ** **.**:*:*:** ::**:* *******.* **.***** * * ***** ********** *:* . .: .. ::.**::**.**. *:***.** ** *********:*. *.***:* ************************.*******************:*** *:* : ::::* *****.*** *:*:* : .* .:* :. .* * ::*..*** *::.: :* * . *****.* ***:**.**: *:: *::*****:**:**..:::***:* * . ***:******.*: .**: :*** * *:.::.**** * * * : . . *. . . :* . . . .. . . ", "identical_positions": 221, "similar_positions": 129, "identity": "26.15%" }, { "cls_id": "homologset.agr.FB:FBgn0003268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G9X6-1", "uniprot_id": "A0A8I6G9X6_RAT", "id": "A0A8I6G9X6-1", "name": "", "aln": "---------MWNNIELLTSDDTGSGFLNVGSRKESVTALYQVDLLGKISS-EKTSLSPKIQACSLSDGFIIVADQSVILLDSTCRSLQLFLIFDTDVDVVGLCPEGKFLFVGERSGNFHLIYVTSKRTLFTKAFVEKAEDE--RTYRSLVIEKDGSNEGTYYMLLLTNNGFFYITNLQLSQIEQAIENTDLDSAKKLQGQFKCSFISTESYHSSGCLNLLASQSGKFANETSVIIGGTGSCAFSKWEPDSTKKDMSLKNFVDTDIIRGAKSFQLIDNLLFVLDTDNVLSLWDAYTLTPVWNWPSLPIEQFLLTTEADSPSSVTWQGITNLKLVTLTAT-TKEKMRNLIIYSLPTMEILYSLEVSSVSSLVQTGISTDTIYLLEGVHKNDPNLCEDSVSNLELRYLTEVLPENRLSRLLHKHRFADAESFAIQFGLDVELVYKVKSNDILEKLALIS-DKSEQSEWQQLVDEAKENLCKIQDDDFVVNFCLKAQWVTYETTQEMLSYAKTRLMKKEDRTLPACSDDFLEVLKAHAKLTTFYGAFGPEKFSGSAWVEFLNNEDDLKDIFVQLSEGNFDCAQYLWLRHRADFESKFDVKMLENLLNSISTQIPVEKLCSWFKNDVIPFVRRIVPEGQNILAKWLEQASRNLELTDKANWPENGLQLAEVFFTAEKTDKFGFSSSWHWISLKDYQNTEEVQQLRTLVSKLQELIILHRKYNCRLALSEFEKENATTVVFRMFDRVSAPELIPSVLEKFVRVYIREQNLQEEELLLLYIEDLLKRCSSKSMTLFDTAWEAKAMAVIRCLSDTDLIFDAVLKIMYKAVVPWSAAVEQLVRQHLEMDHPKVKLLQESYRLMEMKKLLRGYGIREVNLLN-KEIMRVVRYILKQDIPSSLEDALKVAQGYRLSDDEIYSLRVIDLIDRDQGEDCLLLLRSLPPSEAEKTAERVIIWARLALQEEPDGSEEDKAWRISVAKTSMDILKILCDIQKDNLQKKDDAEEFLKRFKMVASLQENFEVFLPFEDYSDTGLVAGLREQYIKAQENAQAEHKFR----------------GPPGPTPAMGTNASVKSKLHRQALVLQVSTQELEAEMALRALKDGKVAVALSKCRDLLKHYCNADTGRLLFVVCQKLCHMLADDVPMVAPVGLNLPSEIHDLTCHAVTICSPDFLLDVLELSKYTLTAVELCRQCQMDDCGILMK-AAVGTHKDPYEEWSYSDFFSEDGIVLESQVVLPVIYELISSVVPLAEGKRRPLDSISLPYCSTSEGENLILPLVSSISALLRNLQESSQWELALR--FVVASFGTCLQHSVSNVMSMSLSEKLLGKSTLASSRQIIMELKEKSIAFIRGS----ATTLLHKVFN--CRLVDLDLALAYCTLLPQKDVFENLWKFIDKAWQNYDKILALSLVGSRLANLYQDVETGLRFHELSIDAKWGIRLGKLGISFQPAFRQNFLSKKDLIKALVNNIDMDTSLILEYCSTFQLDSDAALRLFIETLLRN--------TTS-QSQGGDAPEPTQHQHSKLLQKATEMVPLLKSTKDLVISLTEILYKLDPYDYEMIEVVLKVIEQANEKITTVNINQ-ALNLLRHLKSYRRMSPPVDLEYQYMLEHLIT---LPPAAQTRLPFHLILFGTAQNFWKILSSELSEESLPTLLLISKLMKFSLDTLYVSTAKHVFEKNLKPKLLKSAQARSS-VMSKEVDKLVQTLESYLLSIVNPEWAVAIAISLTQEIPEGPFKMTSLKFCLYLAERWLQNIPPQDETCEKVKALQKKLYLQFRLSGTEAVLIAHKLNDQEYLRVVGKPAHLIVSLYEHPSISERLCTTSGKDYPDIHAAAKEIAEVNEINLEKIWDMLLEKWLCPSTAPGEK----ASEFFELEEDEVLHR-VVYLLQARPIDYSSRMLFVFATSATSTLG--IRQLTFAHRAR--ALQCLLYLADKETIESLFKKPTEEMKSYLKCITFLASFETLNIPITYELFCN--SPKEGMIKGLWKNHSHEPMAVRLVAELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLSCISSVHSLWQVPYFSKAWQRVIQIPLLSASCPLRPSQLADCCESLVAILECPVSDDLDMMGVAKQYVQLELPAFALTCLTLMPHSEKRHQQIKNFLNSCDAQIILQQLEEHMNAGQLAGLSQQIRSLVLNHVVNKKEFGILAKTKYFQLLKRHVIN---TDNVTELVNYLANDLSLDEASSLITEYSKHCG----KPVPADTAPSEILKTFLGS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3Y4-1", "uniprot_id": "KNTC1_MOUSE", "id": "Q8C3Y4-1", "name": "Kinetochore-associated protein 1", "aln": "---------MWNNIELLTSDDTGSGCLSVGSRKENVTALYQADLLGKISS-EKTSLSPKIQAFSLSHGFIIVADQSVILLDSICRSLQLFLIFDTDVDVVGLCQEGKFLFVGERSGNFHLIYVTSKQTLFTKAFVEKALDESQRTYRNLIIEKDGSNEGTYYMLLLTNNGFFYITNLQLSQIEQAIENTDLDSAKKLQGQFKCSFISTENYHS--CLSLVASQSGTFASKTSVIIGGTGSCAFSKWEPDSTKKEMSLKNFVGTDIIKGAKSFQLIDNLLFVLDTDNVLSLWDAYTLTPVWNWPSLPVEQFVLTTEADSPSSVTWQGITNLKLVTLTAT-AKEKMRSLIIYSLPSMETLYSLEVSSVSSLVQTGISTDTIYLLEGIHKNDPNLCEDSVSDLVLRYLTEVLPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNDMLEKLALISSDKSEQSKWQQLVDEAKENLCKIQDDDFVVNFCLKAQWVTYETTQEMLSYAKTRLMKKEDRALPASSDAFMEVLKAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLRDVFLQLSEGNFACAQYLWLRHRADFESKFDVKMLENLLNSISTQFPLENLCSWFKNEVIPFVRRIVPEGQNILAKWLEQASRNLELTDKANWPENGLQLAEVFFTAEKTDRFGFASSWHWISL-DYQNTEEVRQLRTLVSKLRELIILHRKYNCKLALSDFEKENATTVVFRMFDRVSAPELIPSVLEKSVRVYIREQNLQEEELLLLYIEDLLKRCSSKSMTLFDTAWEAKAMAVIRCLSDTDLIFDAVLKIMYKAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLN-KEIMRVIRYILKQDIPSSLEDALKVAQGYRLSDDEIYSLRIIDLIDREQGGDCLLLLKSLPAAEAEKTAERVIIWARLALQEEPDGSEEDKAWRISVAKTSVDILKILCDIRKDNLQKKDESEEFLKRFQMVASLQENFEVFLPFEDYSNTALVAGLREQYIKAQEAAQAEHKHR----------------GPPGPTPARGTHLSIKSKLHRQALALQVSEQELEAELTLRALKDGKVVAALSKCRDLLKHYCNADTGRLLFVVCQKLCQMLADDVPMVAPGGLSLPSEIHDLACHAVTICSPDYLLDVLELSKYTLTAVELCRQCQMDDCGMLMK-AALGTHKDPYEEWSFSDFFSEDGIVLESQVVLPVIYELISSVMPPAESKRHPLDSISLPYCSTSEGENRILPLVSSISALLRSLQECSQWELALR--FVVGSFGTCLQHSMSNVMSISLSKQLLGKNTLANSRHIIMELKEKSITFIREN----ATTLLHKVFN--CRVVDLDLALAYCTLLPQKDVFDNLWKFIDKAWQNYDKILALSLVGSQLANLYQDIETGLWFHELSIDAKWGIRLGKLGISFQPAFRQNFLTKKDLIKALVNNIDMDTSLILEYCSTFQLDSDAALRLFIETLLRN--------TSS-QSQGDAAPESTKHQHSKLLAKATELVPLLKNTKDLVISLSEILYKLDPYDYEMIDVVLKVLEQANEKITSVNINQ-ALNLLRHLKSYRRISPPVDHEYQYALEHMIT---LPPAAHTRLPFHLILFGTAQNFWKILSSELSEESLPTLLLIAKLMKFSLDTLYVSTAKHLFEKNLKPKLLKSAQARSSTLMSKEVDKLMQTLESYLLSIVNPEWAVAIAISLTQEVPEGPFKMSSLKFCLYLAERWLQNIPPQDETCEKAKALQKKLCLQVRLSGTEAVLIAHKLNDQEYLRVIGKPAHLIVSLYEHPSISERLCTTSGKDYPDIHTAAKEIAEVNEVNLEKIWDMLLEKWLCPSTVPSEK----ASEFFELEEDEVLHR-VVYLLQARPVDYCSRMLFVFATSATSTLG--MRQLTFAHKAR--ALQCLLYLADKETIESLFKKPIKEMKSYLKCITFLASFETLNIPITYELFCN--SPKEGMIKGLWKNHSHEPMAVRLVAELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLSCISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLRPSQLADCCDSLVAILECPVSDDLDMMGVAKQYVQLDLPAFALTCLTLMPHSEKRHQQIKNFLNSCDARIILQQIEEHMNTGQLAGFSHQIGSLVLNHVVNKKEFGILAKTKYFQLLKCHVIN---TGNVTELVNYLANDFSVDEASALINEYSKHCG----KPVPADAAPCEILQTFLGGS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50748-1", "uniprot_id": "KNTC1_HUMAN", "id": "P50748-1", "name": "Kinetochore-associated protein 1", "aln": "---------MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISS-EKASLNPKIQACSLSDGFIIVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLLTNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVDFSTAKKLQGQIKSSFISTENYHTLGCLSLVA---GDLASEVPVIIGGTGNCAFSKWEPDSSKKGMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLTTEADSPSSVTWQGITNLKLIALTAS-ANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGISTDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQWITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWIEFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKLCPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTDELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIVFRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLMEMKKLLRGYGIREVNLLN-KEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRIIDLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSVDILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHIKAHEVAQAKHKPG----------------STPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNIKTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAATICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMK-ASFGTHKDPYEEWSYSDFFSEDGIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQNLQESSQWELALR--FVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAVIFIREN----ATTLLHKVFN--CRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISLVGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENIDMDTSLILEYCSTFQLDCDAVLQLFIETLLHN--------TNAGQGQGDASMDSAKRRHPKLLAKALEMVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQ-ALSILKHLKSYRRISPPVDLEYQYMLEHVIT---LPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTLLLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLSIVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLHIQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAAAKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEK----PSELFELQEDEALRR-VQYLLLSRPIDYSSRMLFVFATSTTTTLG--MHQLTFAHRTR--ALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCS--SPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDCSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMN---TNNITELVNYLANDLSLDEASVLITEYSKHCG----KPVPPDTAPCEILKMFLSGLS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B017-1", "uniprot_id": "A0A8M3B017_DANRE", "id": "A0A8M3B017-1", "name": "", "aln": "MKQQSRFLKMWNNVELLLNEDTNTVRLYNDVEQESGNALYQVDNLVKISSSEKVVSKPNVYASSTPNCCIIVVDTAVVLFDPGFQTVLIHLYFDSVVDAVTVCPQGQFLLVGERNGSLHIIYIPLKKTVLTKNLPQQKSSCGETTFKSLILHEKPGSKGDYDLFFVIKDGFLHVSNVALGKIQRAIENMDLVVLNKIQEDILMNFFSTKEIHEDGCISASL---VCFGSTSHLLIGADGANVLSLWSMGLHQTSMSLTKLLDSSLMSEVKKVQVVDNLMYVLNNEGMLSMLDIHSFVMLCCWPDQYIVDFLLISDGNS-SSITQQDDNTLKIMTLVVEGNKDHSRKLVVQSLSSMEVFYSLEVSSESWLIQKGISMDTIYLLEGVLANTKSSPEDPVSTVVIRCFTEALPENRLNKLLYKHKFEEAEKFAKTFGLDVELVYKVKLNVVLEKLISAS-GNDQTIEWPELIQEAKTNLMKIMDEQFVVQYCLSASWPTLSIAEEMLNYTLNRFP-------------CCQIQTALAKLATFSSMYGPNNFDGIKWIEFLNSTDYLKDILALLKEGNVNGAQYLWLRHEGEFASEFDEACFHALLSSISSDIPSQDLIPWFKGVVVPFVWRVLPKGQKIIARWLEHRARNLELTEKSDWPQNGLLLAEL----------GLPSLWRSMGLAEICGAEEVESLRSLVANLRQLCDLYIKYNCHLSLSDYERGSTRSMAFLMLDKVQAPELIPAVVESSVEPYALENGLDLDQTLLDYIKDLLDCCSSQITSLF-TEWEAKAVAVLHCMKDTNKVMDAVIEIMYKAVVPWSDTIEKLVQLHLEKEHPKQELLREGYRLMEIKKLLRCYGIRSLALSNSRDIMMLVRYILKQDLPTSLEDSLKLIEAYKLNPAEFHHLHCIQLIQRNKREKCTTLLKSLPHSEAIFVIERMACWARLELQDKQHISEEQKKLQMLISQIMVEALKYLQSIQTDDAFKKTECENNLKMFTAIAHLQEDFDIFLTPEEYDDPVVRHKFNQQLITAYENTQAWRRSGKQHPDKVSDSNLNGSAAVANDPDGKTKSLSTEAGLHRLARQLQKTEQELWADLALRALDAGNVEKALQILSELYQHHSNCSTGRVLFSTAQRLCQMLEENVPMVLPEKTNLPAVIHRLACQAITVCHSDLLLDCLELCKSTRTAADVYRQCQIEDFGFFAKESSMSGEEDAYAESHFHDVFNEDGIVLDPVSVLPLQYKITRNLLPLSESRLFPFDCSCLSYCSTKEDAELVGPLLNPMASMLQMLQECSQLELAVR--LLMESYGSILLHFVSNNMDISLSKRLQSNNRMARDKQTLDKIEKTVLSSVSVV----VVSLLQKVLN--WRVVDSDLAIGLCTILSKAAVIDILWKIINSAWQNYDKIKVVAMVGAHVSFLYKDEEERGKFVSVITDAEWGVQLGRLGVSIQSVFRQCTETKRNLIPTLVKNKNITPDIILHYCSTFGLDSYSAINLYITTLLLQEDRWYEMEIEEGDAESSLRIQESLRGKDDMLESALQIIPQLGSTKDLVISLNTALTKLNPYNYEWIERVLKTIQMADESTTLIPLGQ-MVGLLQHLKSHRRISPPTDLESSYLLENSLE---PTALANTRLPFHLLFQ-SSHAFWKIVSPELSEETLPTLLLICKLMKVNLDKLYVLAVNHVFKKSLLPLLMDQTKKIQHLGSSKELCSVTDSVFQHALCIQNLELAAATVHKIAQDLPAGAVKTDFLKFSLDLVHKLLKSDTLEESLQARGEALISKLQLQYQRSATENALLSSQLGSPELLKLTGLPGRLIVALFEHSSVLDRMKNPAGQTYPDIHSVASEIASINSVDLLKIRNILLEKWLCQTGQSNGKDINHQDNVTDVNDDPDLMR-VVYLLQMHPMDISARLLSPVLTSQTWPLGGSGLRLTFEHRSR--ALLCLTHLTDAATLETLSNQPSSKIKYYLKCYMYLAQMEALNIPYTLDMFIS--SPKEGMIKGLWKNHNNEPQAVRLVADLCLEYGVYDLQLWNSVLQKLISFNMTSYLQKVLEALIAVPSLLEGQSLSRIWRSVIQAPFLTASLPLSPQQHMVMYKTFVLLLKCPFLFTLDLVAIAKRFSQFSLQAFSLGTLLLIPCLKKKEPQIQSFLLSCNPTLILDQTEESMATGELAGIPSQIRETVFAFLCQNGKSQTLLKTKHFTYLKRHLISKGRSEAVLELLNCLVEQKGEDEAICFANEYLQYRDLKGEKTAPVSDPFSDPVRDLLEKVLESRGTQTVT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9W7-1", "uniprot_id": "Q9V9W7_DROME", "id": "Q9V9W7-1", "name": "", "aln": "---------MWSNFEASS------------LEDETISNIFSSRGIFQISSEEEVNKYPDVMASVQCGKMVIGIDKSLLLLEDELVAKCSFLAFGAAIEAIAISSSGNLIVCGLSDGEVHGVFIKG-LLLFSVAVNLEDVSLTGGTFRSIHQLDQRFYFTCKNGSIYSLSDIDETCLETLGNMSLNENETIACEKALLEDVTIQRLSKGRSSCSVDCAVLLKR---LLTGNISAENNQDDLEAQPGLVITGDQSTMNFRNAANDVTRINLPAQYGSLKQIFNLEH-YIIALTDSGHLVEICPYTRTVYMCQTTQQKNLLIEDLLVMECSEDNIELLVLTKSTAEGRFIKIVEYPTLNVKNEVEVPDHAWLVRQPKCAVNLYYLAAKEVNQSSIP----SVVEMMLVSETDPSDRFKKLICKGRLEEAEEFGKQFELCLQPIYEAKAKRILVELCNSN-----SQNVDTKFQDLLQLLSQVESKAFIKSHRMIN-LNSRHILERYLHEVKKRLTFEDDE------EDMLEIDEQLHRLKTLA-IIDPYECN-TDWQKFIYDNN-LVRMVKSLFNTDMPTACLIWRRHSSSILPLLNEDELRTLLGFIPSNTKPFNVVQWLR-QFIPMVSNTHPSIMPFITDWSIEMTRNLQYS--PHWPDIGLEFCTKILD-------IFEEIQFTYSDVRRQQERNVGKLRDLVNALQDLSVLKTNYNMGFTLDNYMQDSIDATALSILQHVQLDKLQR-LVKNFMYPIFQEKGRQPLDVIKQYISQLVASRLSS------SSWLDRAMACIELLHNEDSRLECALSVLQNAPVPWPDTLAPLIRLR-ASTHPLAVKINAEYEIQVIKIMKVKYGWPADSSDINLELFMMR--IVKLNLPDMLDDISALTKAAPELSTSANFNCCYQMARRGQVEMAYEFFKKLNGEKNSKSAKEVVEIMANILENSSSASFES-DIKVQEHLNVLELFKLFLPHVESVYERRYLVIKHRFRLRKFGILLSCSSELIPLHRR-HCLLDEAIERIIERAQATLNVSAFIAS--------------EISELCTALGLPKVFGLHRICQRIGCLPLSCALAYHVVSFVDCVPANAGEFVNLALELLVQQIESAKGKNQETASSLQLINENDPLSFYLAYELLTSALLHESSRRHDLVELIKYIR--VAVIHYPLDAIKSHYDGKEQAVNEHIC-RALDGISVALGETTINFSCALNGSFDVKTLTVPTTTKKRYSVSMFDEVEVQPIQQQPQ-KKSVGGRMAIVKFLARTLLLMVIETEPNNSLLMQVRNELPENTKADVESACADFFLSLEHLTKVKEHDAWYVMSQYLLDFQKQNCRTKRIINEGFITLQLRRIFRNAMGSKDVNFIELFTMLVVDSEALALLEKLSVEVKTDLQKINFLTLS-AMYHEHIEDLDSVHMIRTKRLKLFYYLEFCQQDHRIKGKFNADMDNIEDLLKEFHN-KQLDVQLLERMSKDFGFDYQKILITQILSILSAQELR----FEVKRDTFGDEELVMLSSAQEMRDMCQPYINEINNVELFTSKLKHFIEDINIYFYELYMCVINILMYFDSAPKEMEIWMNILHFLRHKMITRRRNRPGQVETDTWLKSQRENGVMPKISRYRLPFKPIVEQPLKDILDSELNVDNCQSWFPLIQMYTALKGSKDSSQNCDYFCMSAVKNSISEYKSKNDSESWSLHPTNNAFLQSILRLVEKVNNPNKAFLILYFVSNYARDGADQVEASYECWKFVKEKGHLITD-----PKSREQVAKVKRRYPIQKTQHLLYVYGLTDEKLLRQVENPTELIQALYHHELILK-------SSKVDINALVAEIAKLHDLCLATIQYRLLQKWLALTMESAGDGTILEETFMEEQNWPEQANGAESSNSQDASENVNRAFYILSSWPKAEAVKFLVGLIFKGGSVNTSTQLQMYECYSKLNDGSNSFTNTISQRQFISIKCVHELKALGYKSNLEKFSDDHCNKIDILKMIWQRNAQNPLSLEVMANICLGFDIHLPQIWNGILKRMVMFHMVRELNALLDVLSCRPHLLHLDGLAQAWDYVLCHPLQNAVELRSFKQEEVLHKTLLRLQGCPVVHALNLLQFAQLCIVVHRPHMAASLLSFCQSSEQR-QKIKKMIHSHPVENLRQQILDLEDAGILP--------VVLNFALKELNL---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:.* ..* . ::. : :*** *:. *.: * :* * :::*:: : .* *.: ::.: :. .*:::. * .*..* :.: ::: . : . *::.: .. : ..: * ::. :: :: : . .. * : . . . . . :. *.. : . : :: *: :::: * :. : :. . ..: . :: *. . . : : : . .::: .:**.. : *:: . .:* * . * . * : : .:*. *.:*:.:*: * :: :**.*. * * :: :*:.* : :* :* . : .:: * :: .. *: .. : : :. * . .*: :: :* *: .* : . * :*: . : * :. * : :. * :* ** ..: . :: :. **. :.:. .: *:: .:*:* . *. ::: * . :***: : ..**: ** :. : . . .:* .** ** *::* * :** ::*.:: : . : .: ::::* :* :::. : *:. : : : **.:*: *. : * :*:* : : : : ::..:.:: * ***. :: *:: : ** :. *.: :* : ** ::: : *:* ::* *:* : :. . :: * : . :::.* : :.: *::. * * :: :: :* : . :: : : .. * . . ::. . . : :.. * :. : : * : ::: .: :. :* :. .*: ... : :.. . .: :* : : : . : : : : . * . : : : . :.. . . * :* . .:* : .: * . *:: * : : .: :: : .. : :* : : . . :. :: . : : .::: . *::::. * :: :: . .: * *: .. : :** ::: : :: : : . : :.: : . :: *. . .:*: : : :: .:: . .. * :* : * ::* . .: . : : ..: :. .*. : .:: * ** *:: : :. . : : : :*:* ** . * : * . *: . :. ****: :. . : : . . :: .*: : . :* . *. : . . : . . ::: : * : * ::: *. : . :... : . : . *: : . *: * * : *: * .** :*:.* : . **:: . ***.::.: * .: **:***. : . . . . : :: . . . : * : . : . * * : : : : . . : : . : .:::*. . : * . . * .::* :*:.: ::. ::.:::::** : :: *:**.:*:::: *:* *. :*. : . * . ::: * *: *: .* .* .::: : **. *::: .*: . :: * : ::: :*:.:: * : .* : :* *. :: :: : ", "identical_positions": 222, "similar_positions": 682, "identity": "9.7%" }, { "cls_id": "homologset.agr.FB:FBgn0003270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH80-1", "uniprot_id": "A0ABK0LH80_RAT", "id": "A0ABK0LH80-1", "name": "", "aln": "------------------------------------------------------MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAAR----------------------------------------------------------------RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIVALTRILAEAER-------------DWVGLRCEQ----------------RGRNHPYLPFPGARLQVDPEPYGQKFFGFQPESFPMAS----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E5-1", "uniprot_id": "ATOH7_MOUSE", "id": "Q9Z2E5-1", "name": "Transcription factor Atoh7", "aln": "------------------------------------------------------MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAAR----------------------------------------------------------------RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAER-------------DWVGLRCEQ----------------RGRDHPYLPFPGARLQVDPEPYGQRLFGFQPEPFPMAS----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N100-1", "uniprot_id": "ATOH7_HUMAN", "id": "Q8N100-1", "name": "Transcription factor ATOH7", "aln": "------------------------------------------------------MKS-CKPSGPPAGARVAPPCAGGTECAGTCAGAGRLESAAR----------------------------------------------------------------RRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGS--------ERDWVGLHCEH----------------FGRDH-YLPFPGAKLPGESELYSQRLFGFQPEPFQMAT----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW52-1", "uniprot_id": "ATOH7_DANRE", "id": "Q8AW52-1", "name": "Transcription factor atoh7", "aln": "----------------------------------------------------------MKPR--------RPSCADSGSDSDSRD-PEKFESAMR----------------------------------------------------------------RRMAANARERKRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALNRILSDAGRHVDP-------QKDWLNLQFDG----------------LQTEGYFMHYDSP---VESD-CMLSSFSYHYESL--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZQL9-1", "uniprot_id": "D3ZQL9_RAT", "id": "D3ZQL9-1", "name": "", "aln": "MSRLLHAEEWAEVKELGDHHRHPQPHHIPQLTP--QPPATLQARDHPVYPAELSLLDSTDPRAWLTPTLQGLCTARAAQYLLHSPELGASEAAAPGDEADGQGELVRRSGCGG-LSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSVGEQPPPPAASCKNDHHHLRAAASYEGGAGASAVAGAQPAPGGGPRPTPPGACRTRFSTPASSGGYSVQLDALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVPEDSSKTSPRSHRSDGEFSPHSHYSDSDEAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48985-1", "uniprot_id": "ATOH1_MOUSE", "id": "P48985-1", "name": "Transcription factor Atoh1", "aln": "MSRLLHAEEWAEVKELGDHHRHPQPHHVPPLTP--QPPATLQARDLPVYPAELSLLDSTDPRAWLTPTLQGLCTARAAQYLLHSPELGASEAAAPRDEADSQGELVRRSGCGG-LSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPNVGEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAPGGGPRPTPPGPCRTRFSGPASSGGYSVQLDALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVQEDNSKTSPRSHRSDGEFSPHSHYSDSDEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92858-1", "uniprot_id": "ATOH1_HUMAN", "id": "Q92858-1", "name": "Transcription factor ATOH1", "aln": "MSRLLHAEEWAEVKELGDHHRQPQPHHLPQPPPPPQPPATLQAREHPVYPPELSLLDSTDPRAWLAPTLQGICTARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDSALTAMMAQKNLSPSLPGSILQPVQEENSKTSPRSHRSDGEFSPHSHYSDSDEAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0A7-1", "uniprot_id": "AMOS_DROME", "id": "Q9Y0A7-1", "name": "Basic helix-loop-helix transcription factor amos", "aln": "MLTNNELMEQFYFPDEAPAIPEFLSNDTFQQLEQLMYQQEFSTSDSQSDGANSCSLEMYYDTPSVLELEHMLNAQEQQQHHLQANPLGKNQGRSPRYWNKQQRSKPYDKLSTS---------------------MSSSTSSASSSSSSSAGFGGEVLKKRRLAANARERRRMNSLNDAFDKLRDVVPSLGHDRRLSKYETLQMAQAYIGDLVTLLSRDY---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9Q9E7-1", "uniprot_id": "A0A8M9Q9E7_DANRE", "id": "A0A8M9Q9E7-1", "name": "", "aln": "-----------------------------MPHPDTPFGQFIWRETDRSHSEQCPKAPMGWREEQLQDRASCDPCALVQLRLTGLSYSSEEQSSIAR-----------------------------------------------------------ARRRRRLAANARERRRMLGLNVAFDRLRSVIPNVESDRKLSKSETLQMAQIYISTLSELLEDKDCDPETP---------YPTLTMQD---------------QDITKGLPMTEETKTELKNNPTCRIRSYNGNFGCLTCSDHKTAELLVDSHCLERNNGVK--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. **:*******:** .** ***:** *:*. *::*** ****** ** * :* ", "identical_positions": 34, "similar_positions": 11, "identity": "9.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4D5-1", "uniprot_id": "D4A4D5_RAT", "id": "D4A4D5-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDEDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02401-1", "uniprot_id": "RLA2_RAT", "id": "P02401-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZN03-1", "uniprot_id": "D3ZN03_RAT", "id": "D3ZN03-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEAEDERLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDNMGFDLFN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A5F8MPY2-1", "uniprot_id": "A0A5F8MPY2_MOUSE", "id": "A0A5F8MPY2-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILGSVGIEADDDRLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P99027-1", "uniprot_id": "RLA2_MOUSE", "id": "P99027-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGK-NIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05387-1", "uniprot_id": "RLA2_HUMAN", "id": "P05387-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGK-NIEDVIAQGIGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05389-1", "uniprot_id": "RLA2_DROME", "id": "P05389-1", "name": "Large ribosomal subunit protein P2", "aln": "MRYVAAYLLAVLGGKDSPANSDLEKILSSVGVEVDAERLTKVIKELAGK-SIDDLIKEGREKLSSMPVGGGGAVAAAD--AAPAAAAGGDKKEAKKEEKKEESESEDDDMGFALFE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02400-1", "uniprot_id": "RLA4_YEAST", "id": "P02400-1", "name": "Large ribosomal subunit protein P2B", "aln": "MKYLAAYLLLVQGGNAAPSAADIKAVVESVGAEVDEARINELLSSLEGKGSLEEIIAEGQKKFATVPTGGASSAAAGA----AGAAAGGDAAEEEKEE--EAKEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05319-1", "uniprot_id": "RLA2_YEAST", "id": "P05319-1", "name": "Large ribosomal subunit protein P2A", "aln": "MKYLAAYLLLNAAGN-TPDATKIKAILESVGIEIEDEKVSSVLSALEGK-SVDELITEGNEKLAAVPAAGP--ASAGG----AAAASGDAAAEEEKEE--EAAEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*:*** .*: * .:: :: *** * : ::..::. * ** .::::* :* *::::*..* .:*. ..*.:. * :*:* * *..*::*** **:", "identical_positions": 33, "similar_positions": 45, "identity": "28.45%" }, { "cls_id": "homologset.agr.FB:FBgn0003275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88828-1", "uniprot_id": "RPAB2_RAT", "id": "O88828-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDNE----------DNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILP---SGERP------------------QANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61219-1", "uniprot_id": "RPAB2_MOUSE", "id": "P61219-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDNE----------DNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILP---SGERP------------------QANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIISD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61218-1", "uniprot_id": "RPAB2_HUMAN", "id": "P61218-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDNE----------DNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILP---SGERP------------------QANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24320-1", "uniprot_id": "RPAB2_DROME", "id": "Q24320-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MDDADYDN-------DDVGGDDFDDVDED--VDEDINQEEE-ADNIEIIAPGGAGGGG------------------VPKSKRITTKYMTKYERARVLGTRALQIAMCAPIMVELDGETDPLQIAMKELKQKKIPIIIRRYLPDHSYEDWSIDELIMVDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20435-1", "uniprot_id": "RPAB2_YEAST", "id": "P20435-1", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "aln": "MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVT---GGNGPEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* : ::.. :.*.* : : : * :. *:. .* .:.:* ** *********:********:* **::*:*:****** ****** :***::******* *:***.::***: ", "identical_positions": 61, "similar_positions": 35, "identity": "38.36%" }, { "cls_id": "homologset.agr.FB:FBgn0003277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24928-1", "uniprot_id": "RPB1_HUMAN", "id": "P24928-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG--GRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV---NEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR----ISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08775-1", "uniprot_id": "RPB1_MOUSE", "id": "P08775-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG--GRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV---NEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR----ISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPASPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5A6-1", "uniprot_id": "D4A5A6_RAT", "id": "D4A5A6-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG--GRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV---NEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDVTRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVAR----ISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPEDSDEEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04052-1", "uniprot_id": "RPB1_DROME", "id": "P04052-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "----MSTPTDSKAPLRQVKRVQFGILSPDEIRRMSVTEGGVQFAETMEG--GRPKLGGLMDPRQGVIDRTSRCQTCAGNMTECPGHFGHIDLAKPVFHIGFITKTIKILRCVCFYCSKMLVSPHNPKIKEIVMKSRGQPRKRLAYVYDLCKGKTICEGGEDMDLTKENQQP----DPNKKPGHGGCGHYQPSIRRTGLDLTAEWKHQ---NEDSQEKKIVVSAERVWEILKHITDEECFILGMDPKYARPDWMIVTVLPVPPLAVRPAVVMFGAAKNQDDLTHKLSDIIKANNELRKNEASGAAAHVIQENIKMLQFHVATLVDNDMPGMPRAMQKSGKPLKAIKARLKGKEGRIRGNLMGKRVDFSARTVITPDPNLRIDQVGVPRSIAQNLTFPELVTPFNIDRMQELVRRGNSQYPGAKYIVRDNGERIDLRFHPKSSDLHLQCGYKVERHLRDDDLVIFNRQPTLHKMSMMGHRVKVLPWSTFRMNLSCTSPYNADFDGDEMNLHVPQSMETRAEVENIHITPRQIITPQANKPVMGIVQDTLTAVRKMTKRDVFITREQVMNLLMFLPTWDAKMPQPCILKPRPLWTGKQIFSLIIPGNVNMIRTHSTHPDEEDEGPYKWISPGDTKVMVEHGELIMGILCKKSLGTSAGSLLHICFLELGHDIAGRFYGNIQTVINNWLLFEGHSIGIGDTIADPQTYNEIQQAIKKAKDDVINVIQKAHNMELEPTPGNTLRQTFENKVNRILNDARDKTGGSAKKSLTEYNNLKAMVVSGSKGSNINISQVIACVGQQNVEGKRIPYGFRKRTLPHFIKDDYGPESRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRRLIKAMESVMVNYDGTVRNSVGQLIQLRYGEDGLCGELVEFQNMPTVKLSNKSFEKRFKFDWSNERLMKKVFTDDVIKEMTDSSEAIQELEAEWDRLVSDRDSLRQIFPNGESKVVLPCNLQRMIWNVQKIFHINKRLPTDLSPIRVIKGVKTLLERCVIVTGNDRISKQANENATLLFQCLIRSTLCTKYVSEEFRLSTEAFEWLVGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTAIYYDPDPQRTVISEDQEFVNVYYEMPDFDPTR----ISPWLLRIELDRKRMTDKKLTMEQIAEKINVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLSDMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDPIRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAITRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLLLDAEKCRFGIEIP-NTLGNSMLGGAAMFIGGGSTPS--MTPPMTPWANCNTPRY-FSPPGHVSAMTPGGPSFSPSAASDASGMSPSWSPAHPGS--SPSSPGPSMSPYFPASP-SVSPSYSPTSPNYTASSPGG-----------------ASPNYSPSSPNYSPTSPLY--ASPRYASTTPNFNPQSTGYSPSSSGYSPTSPVYSPTVQFQS--SPSFAGSGSNIYSPGNAYSPSSSNYSPNSPSYSPTSPSYSPSSPSYSPTSPCYSPTSPSYSPTSPNYTPVTPSYSPTSPNYS-ASPQYSPASPAYSQTGVKYSPTSPTYSPPSPSYDGS---------------------------------PGSPQYTPGSPQYSPASPKYSPTSPLYSPSSPQHSPSN-QYSPTGSTYSATSPRYSPNMSIYSPSSTKYSPTSPTYTPTARNYSPTSPMYSPTAP--SHYSPTSPAYSPSSPTF---------EESED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04050-1", "uniprot_id": "RPB1_YEAST", "id": "P04050-1", "name": "DNA-directed RNA polymerase II subunit RPB1", "aln": "----MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAK--IRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIK--DSKKRFAAIWTLCKTKMVCETDVPSE-----------DDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIP--------NGIHLQRFDEG-TTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVR------PKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMK-----YDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVK------------------------YMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGSN----------------DAMAGG-FTAYG-------------------------------------------GADYGEATSPFG---------AYGEAPTSPGFGVSSPGFSPTSPTYSPTSP----------------------------AYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS-------------------------------------------------YSPTSPAYSPTSPSYSPTSP--------------SYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*** :*.****::**:*:: :**:: :::.** : *.*:*** *** * *:*. :**** .*.*********:*******:**:.* *: .***:.*.*:*:. :* ::: : . :.:**:: :: *** * :** . : * .: .:****. ** **: **.* ..**: .: .: : ::*.*.: :*:*:*: :: **:: ::**:***:* ***** .***:: : : :.:****.**:**:* * .*. * .**. *.* * .:******* :**::.* *:*:****:*:*::: ********:*****************: **** :******:*** .:*:.*:***:****: :***.* .::*****::**.*:*****: :..*::** *:*****: *.* *:*****:*******.***:::*:****:*** *:**************:*** *****:.:: .* *::**:*:* ******** .:**:* **.*: :*:*:* ::. **. :* *.*:**:***:****:*: ** :. * : *.* . :** *. ::: .*::*:*:: **::*:* *.*:*: * * :: ::.***.*:* *** :*.: ****:*** * .:* ::* :**..*::* ::*: * .. * ***::**::* *:**:****:* *: .*.: **.* **::*:*** ***:*: * ****.******.:** .****** ****.***:******** **** **:***************************:*::*.:**:** *.***:.:::*: *****: . :* *.: *: *: :***:::.* * : .:: .. . *: *:.:: .**. ** :* *::: ** *: *:* *.*: ***: *:** :: *** * :. ::: *.: : ::*:.:*. ** :** *.:: : :*:**: :**:*::.:**::* :: .:******.*****:*************:***::*:** *******::*::*: *:*****:* * * *:** : . :*****:.** : *****:*: **:.**:* :::::.: * : : ******:**** *.*:.*** *:.*:*: * :** *:.:** :**::* *::. .. :. : ::* :*: ** .** ::**:*:* * :* * .: : : **: **:*****..: .*:: .:** * :*.: :*: ****** * :: :*: *: * ******:*** *.** :* * ::****.**.:**.**:*******::*::*.* .* * :*****:::**:. ***.**:::* *. * :: ** . . . *** . *.:. . .* :.* ...*. ::. :. : :.*:*.:. *..:**:*. ****** :***:*..***.*************:*********.******.******.*:*.:********.** :**.*:*:** ** *. .******:***.*** *:*:** ****** ***:** .**.*** ***. . *:*:*.:******:*:**: *** ** ***. . . .. ", "identical_positions": 831, "similar_positions": 527, "identity": "41.97%" }, { "cls_id": "homologset.agr.FB:FBgn0003278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54888-1", "uniprot_id": "RPA2_RAT", "id": "O54888-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDVDSRWRNLPSGPSLKHLTDPSYAVPPEQQK---AALQDLTRAHVDSFNYAVLEGLS-----------------HAVQAIPPFEFAFK---DERISLTIVDAAISPPAVPKGTI-CKELNIYPAECRGRRSTYRGKLTADISWAVN-GVPKGIIKQFLGXVPIMVKSKLCNLYNLPPQVLIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKSRGLGYTQFGVSIHCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEEDSFFKNSVSQMLRIVMEEGCHTQ--KQVLDYLGERFRVKL-SLPDWYPNAEAAEFLFNQCICIHLKSN--TDKFYLLCLMTRKLFALARGECMEDNPDSLVNQEVLTPGQLFLMFLKEKMENWLLSIKIALDKRAQKTNVSINNEN---LMKIFSMGTELTRPFEYLLATGNLRSKTGLGFMQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRKLLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTK--FVYTASIPALLCGLGVTPVDAAPCRPYSDCYPVLLDGVMVGWVDKELAPEVADTLRRFKVLRER-RCSSLDGGGPDSHDRKAKPVPRAVPLHHSLQAGEACAEPGAGQRRARWNYGAALHEHCHLRGRGFWWSFHTPGALPSQPAEVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPCMYDHYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGD---DSLVFGVKPGDPRVMQKLDNDGLPFIGAKLEFGDPYYGYLNLNTGEGFVVYYKSKENCVVDNIKVCSNDTG-SGKFKCVCVTVRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWS-AMRNRKYNCTVCGRS-------------------------------DSIDTVSVPYVFRYFVAELAAMNIKVKLDVI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70700-1", "uniprot_id": "RPA2_MOUSE", "id": "P70700-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDVDGRWRNLPSGPSLKHLTDPSYGIPPEQQK---AALQDLTRAHVDSFNYAALEGLS-----------------HAVQAIPPFEFAFK---DERISLTIVDAVISPPSVPKGTI-CKDLNVYPAECRGRKSTYRGRLTADISWAVN-GVPKGIIKQFLGYVPIMVKSKLCNLYNLPPRVLIEHHEEAEEMGGYFIINGIEKVIRMLIVPRRNFPIAMVRPKWKSRGLGYTQFGVSMRCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEEDSFFRNSVSQMLRIVIEEGCHSQ--KQVLNYLGECFRVKL-SLPDWYPNVEAAEFLLNQCICIHLQSN--TDKFYLLCLMTRKLFALARGECMDDNPDSLVNQEVLSPGQLFLMFLKEKMENWLVSIKIVLDKRAQKANVSINNEN---LMKIFSMGTELTRPFEYLLATGNLRSKTGLGFLQDSGLCVVADKLNFLRYLSHFRCVHRGAAFAKMRTTTVRRLLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTK--FVYTASIPALLCGLGVTPVDTAPCRPYSDCYPVLLDGVMVGWVDKDLAPEVADTLRRFKVLREK-RIPPWMEVALIPMTGKPSLYPGLFLFTTPCRLVRPVQNLELGREELIGTMEQLFMNVAIFEDEVFGGISTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQNRSDNKLYRLQTPQSPLVRPCMYDFYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGE---DNLVFGVKPGDPRVMQKLDDDGLPFIGAKLEYGDPYYSYLNLNTGEGFVVYYKSKENCVVDNIKVCSNDMG-SGKFKCICITVRIPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPLGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHMCVECGSLLSPLLEKPPPSWS-AMRNRKYNCTVCGRS-------------------------------DTIDTVSVPYVFRYFVAELAAMNIKVKLDVI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Y6-1", "uniprot_id": "RPA2_HUMAN", "id": "Q9H9Y6-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQK---AALQELTRAHVESFNYAVHEGLG-----------------LAVQAIPPFEFAFK---DERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVN-GISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQ--KQVLNYLGECFRVKL-NVPDWYPNEQAAEFLFNQCICIHLKSN--TEKFYMLCLMTRKLFALAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDN---LMRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQ--FVYTASIPALLCNLGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREK-RIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKIKQGD---SSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMYYKSKENCVVDNIKVCSNDTG-SGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWS-AMRNRKYNCTLCSRS-------------------------------DTIDTVSVPYVFRYFVAELAAMNIKVKLDVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20028-1", "uniprot_id": "RPA2_DROME", "id": "P20028-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "MLEEMQQMKTIP----VLTNSRPEFKQIPKKLS---RHLANLGGPHVDSFDEMLTVGLDN----------------SAKHMIPNHWLSPA---GEKISMKVESIWIAKPKVPQDVIDVRTREIYPTDSRQLHVSYSGMCSVRLGWSVN-GVQKTPINMDLGEVPIMLRSKACNLGQATPEEMVKHGEHDSEWGGIFVIRGNEKIVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQTVREDESSLSNVVHYLNNGTAKFMFSHVKRLSYVPVCLILKCLMDYTDEEIYNRLVQGYESDQYYVSCVQAMLREVQNENVYTH--AQCKSFIGNLFRARFPEVPEWQPDDDVTDFILRERVMIHLDTY--EDKFQLIVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKLTSPDALVTSAV---MTQCMRQAGGVGRAIESFLATGNIASRTGLGLMQNSGLVIMAENINRMRYMSHFRAIHRGSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEISMRPDPKLVKAIPKHLIDMGMMPLSNRRYLG-EKLYVVFLDGKHLGHIHQSEAEKIVDELRYGKIFG---TLPQMMEIGFIPFK-KNGQFPGLYIATGPARMMRPVWNLKWKRVEYIGTLEQLYMEIAIDAKEMYPDFTTHLELAKTHFMSNLANLIPMPDYNQSPRNMYQCQMGKQTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNIQLDDFAMGTNAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKKSS---------YFARHPHMPELIKHLDTDGLPHPGSKLSYGSPLYCYFDGEVATYKVVKMDEKEDCIVESIRQLGSFDL-SPK-KMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIAMMIETMAGKGAAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTERLYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQPDTCRLCGDN-------------------------------SSVSMIEIPFSFKYLVTELSSVNINARFKLNEI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22138-1", "uniprot_id": "RPA2_YEAST", "id": "P22138-1", "name": "DNA-directed RNA polymerase I subunit RPA135", "aln": "-MSKVIKPPGQARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFN-ALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEDEISNSGYLGNKLSVSVEQVSIAKPMSNDGVSSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQ-SDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQ--QSDVSRIPSILYSLGVAPASHTFAAG-PSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPS-TRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKLLTKSEDGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . . : . * : .*: **: * . . . :: .:::*..: . *: * ... ::**::.* :* * : *:** * : * :*:*::*: *:* : .* :::* *. .* ** *::.* **::****: ***.*:.: *..: ** .::. *: :: ** :.:: . :**:::* . : * *. :*: : **.* :* :*:: :: . .*.: . :. :** . :. : * .::*: **. : *: .: :. : :: . : :** . :** :: :* :**: . *: :* *: **** * *: *.*::: :: .: . . . : : :: :::***: *::**.: * ** ::*:::* *::**** :***: *: ::** .*:***::***:******** ****:**:: *.: : . ** * .:*: * . . * :** :* : :. . :.* ** *: . . . * : .. : : . . . :**: *:.*.****************** * : .:: ******** :*:.:. ** :*::. * **:***********:****:**:: ****.:*::**:: : * : . *. . . :::** ****. *: :. *.* *:: : ...* . ::.:. .. : : :.:. *: * . *****:** ****: *: :*: *:**:*:*: ***::***.*******.*::*::***..*:** *:**: *.*:::. :***: * .***::*.* :*** * *: ***:.***:******** **:***:**. : * **: **: **:*.********:.**::***:***:: ** : : :* :***:*:. . : : . . . . . : :*: ::*: :**:::.*. : .: ", "identical_positions": 334, "similar_positions": 354, "identity": "27.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50878-1", "uniprot_id": "RL4_RAT", "id": "P50878-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACARPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHCVEEVPELPLVVEDKVESYKKTKEAVQLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIHRR--VLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAAAALAAKSEKIVPEKGAGDKKPAVGKKGKKP-VDAKKLKKPAG--------KKVVTKKPAEKKPTTEEKKSAA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8E6-1", "uniprot_id": "RL4_MOUSE", "id": "Q9D8E6-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACARPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVQLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIHRR--VLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAATALATKSEKVVPEKGTADKKPAVGKKGKK--VDAKK-QKPAG--------KKVVAKKPAEKKPTTEEKKPAA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36578-1", "uniprot_id": "RL4_HUMAN", "id": "P36578-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACARPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRR--VLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVDKAAAAAAALQAKSD---EKAAVAGKKPVVGKKGKKAAVGVKKQKKPLVGKKAAATKKPAPEKKPAEKKPTTEEKKPAA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ASF5-1", "uniprot_id": "A0A8I6ASF5_RAT", "id": "A0A8I6ASF5-1", "name": "Large ribosomal subunit protein uL4", "aln": "--MACACPLISVYSEKGESS-GKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGDGTHRSGQGAFGNMCCGGRMFAPTKTWRRWHCRVSTTQKRYAVCSALAASALPALVMSKGHRVEEVPELPLVVEDKVESYKKTKEAVQLLKKLKAWNDIKNVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWCKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIQRR--VLKKNPLKNLRIMLKLNPYAKTMCRNTILRQARNHKP-SEKAGSRSCCTGSQIREDCSREGGWRQKNCSRQKRKEA-CGWQEAEEACR--------ERGGYQKTSREETYHRRKKACCINY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09180-1", "uniprot_id": "RL4_DROME", "id": "P09180-1", "name": "Large ribosomal subunit protein uL4", "aln": "MSLGNARPLVSVYTEKNEPAKDKNICLPAVFKAPIRPDVVNEVHQLLRRNNRQAYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTFRRWHRKVNVNQRRYALVSAIAASGVPALVQSKGHVIDGVSEFPLVVSDEVQKVQKTKQAVIFLRRLKIWADIQKVYKSQRFRAGRGTMRDRRRIARRGPLVVYDKDEGLRKAFRNIPGIETINVDKLNLLKLAPGGHVGRFVIWTESAFARLNDLFGTWKKPSTLKKGYNLPQPKMANTDLSRLLKSEEIRKVLRDPRKRVFRS--VRRLNPLTNVRQLIKLNPYAEVLKRRAALAAEK-------RTVAKVLAKAKKQNVELAKSHFANVATKAAANRAKLLAARKK---------------KVAAKKPAAKK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49626-1", "uniprot_id": "RL4B_YEAST", "id": "P49626-1", "name": "Large ribosomal subunit protein uL4B", "aln": "----MSRPQVTVHSLTGEAT-ANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGS-ETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFA---------------------------------AEKLGSKKAEKTGTKPAAVFAETLKHD-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10664-1", "uniprot_id": "RL4A_YEAST", "id": "P10664-1", "name": "Large ribosomal subunit protein uL4A", "aln": "----MSRPQVTVHSLTGEAT-ANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGS-ETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFA---------------------------------AEKLGSKKAEKTGTKPAAVFTETLKHD-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::*:: ..*.: : : *****.******:*: *. :.:*:**.***** ********************** *.** *********** **********:*:*: :*. .::*** **:**:.:.:** ::** :: :.*:****. .:: :***:** *: : *: :* *:::***:*. *:** **** ::* :*:*: **:**:**: ** .**:*:****.*:*** ****:** :*::::*: . :: * .*.** : .:*::*:::* **: .:* . : : * : ***.* : :::*****:.: . : : ", "identical_positions": 159, "similar_positions": 109, "identity": "36.3%" }, { "cls_id": "homologset.agr.FB:FBgn0003285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6X936-1", "uniprot_id": "KIRR1_RAT", "id": "Q6X936-1", "name": "Kin of IRRE-like protein 1", "aln": "MTLENRSTCLMTCQSSLLPKKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGHRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT-----EAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPYNLTCRAFN-AKPAATIIWFR--DGTQQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIE-----------------------PQTVLEGERVIFTCQATANPEILGYRWAKGGF-LIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVA--EREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVG---TLERYTVERTNS-------GSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEER------------EVLPVGIIAGATIGAGILLVFSFAALVFFLYRRRKGS------------------------------------RKDVTLRKLDIKVETVNREPLTMHSDREDDTTSISTATRVMKAIYS------------SFKDDVDLKQDLHCDTIETR-EEYEMKDPTNGYYNVRAHED---RPSSRAVLYADYRAPG----------------------------------PTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTP-YEAYDP----------------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W68-1", "uniprot_id": "KIRR1_MOUSE", "id": "Q80W68-1", "name": "Kin of IRRE-like protein 1", "aln": "MTLESPSTRLMTCQSSLLPEKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT-----EAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFN-AKPAATIIWFR--DGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIE-----------------------PQTVLEGERVIFTCQATANPEILGYRWAKGGF-LIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVA--EREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVG---TLERYTVERTNS-------GSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEER------------EVLPVGIIAGATIGAGILVVFSFAALVFFLYRRRKGS------------------------------------RKDVTLRKLDIKVETVNREPLTMHSDREDDTASISTATRVMKAIYS------------SFKDDVDLKQDLRCDTIDTR-EEYEMKDPTNGYYNVRAHED---RPSSRAVLYADYRAPG----------------------------------PTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTP-YEAYDP----------------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96J84-1", "uniprot_id": "KIRR1_HUMAN", "id": "Q96J84-1", "name": "Kin of IRRE-like protein 1", "aln": "-----------------------MLSLLVWILTLSDTFS---------QGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQAT-----EAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFN-AKPAATIIWFR--DGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIE-----------------------PQTVQEGERVVFTCQATANPEILGYRWAKGGF-LIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVA--EREVPLYVNGPPIISSEAVQYAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVG---TLERYTVERTNS-------GSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEER------------EVLPVGIIAGATIGASILLIFFFIALVFFLYRRRKGS------------------------------------RKDVTLRKLDIKVETVNREPLTMHSDREDDTASVSTATRVMKAIYS------------SFKDDVDLKQDLRCDTIDTR-EEYEMKDPTNGYYNVRAHED---RPSSRAVLYADYRAPG----------------------------------PARFDGRPSSRLSHSSGYAQLNTYSRGPASDYGPEPTPPGPAAPAGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTP-YEAYDP----------------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A6Z9-1", "uniprot_id": "A0AB13A6Z9_DANRE", "id": "A0AB13A6Z9-1", "name": "Kin of IRRE-like protein 1", "aln": "-----------------------MQGLLLLLSLALSFHR---------VRT-ARFSQEPADQSVVLGQRVVLSCVVFNYSGIVQWTKDGLALGIGEDLRAWPRYRVLRLVDVGQYNLEISAAELSDDSLYECQAT-----EAALRSRRAKLTVLIPPDEPVIEGSPEILLTAGVPYNMSCVSRG-AKPASVIEWQK--DGLPIEGAVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKRATITLNVHHPPVVTLSIE-----------------------PRSVLEGERVTFTCQATANPPIMGYKWAKGGV-VIQGARESVFVTKADHSFFTEPVSCQVFNAVGSTNVSILVDVHFGPILVVEPKPVTVDVDSDVTLNCKWAGNPPLTLTWTKKGSSMVLSNNNQLYLKSVSQADAGQYVCKAIVPRIGVG--ETEVTLTVNGPPIISSEPFQYAVRGERGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVEQSKPSA----QGGAVLSTLTINNIMESDFQSTYNCTAWNSFGSGTMIISLEEM------------EIVPVGIIAGGTVGCSILLLLCLLALVLFLYRQRKGS------------------------------------RRGVTLGKPDIKVETINKESHSLEEDS----GSVSTATRMVKAMYSFLPSVTLSPSSQPFKDDIDLKQELRSDTLDTR-QDYELKDPTNGYYNVRASTHDEGRPASRSMHYSDYRTSSQPGGAAAVVSSSSGPPPGATAGPGTPSSLAPGSRAGCYDPRPPSRLSHNS-YAQFNTFTR--AGQSQQPPPGSGPQTSDFPAECSLLDSSGQLGYENYGYP--SHYPTFRMGFAPPSLAPLEGGPAYEMYGVGPSVGAGGGAGTPETGLGKYGSSTRFSYTSQHSDYSHRHTQRMQTHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z878-1", "uniprot_id": "A0A8M6Z878_DANRE", "id": "A0A8M6Z878-1", "name": "Kin of IRRE-like protein 1", "aln": "-------------------MGFSMTCLWIVTLAIISVHR---------VFSGPRFSQEPADQSVVIGERVVLSCVVFNYTGIVQWTKDGLALGIGEDLRAWPRYRVLRIMDVGQYNLEITSADLTDDSLYECQAT-----EAALRSRRAKLTVLIPPDGPVIEGSPEILLTAGTSFNLTCVSRG-AKPMSTIEWYK--DGIIVEGAHTSTEVLSDRKRVTTKSFLEIQPMDTDTGRNFTCVASNLAAPLGKRSTVTLNIHHPPTVILSIE-----------------------PRSVLEGERVKFTCQATANPPIMGYRWAKGGV-ILDGARESVFETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGPILVVEPRPVTVDVDSDVTLNCKWSGNPPLTLTWTKKGSSMVLSNSNQLFLKSVSQADAGQYVCKAIVPRIGVG--ETEVTLTVNGPPIISSEPIQYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWEKERGTLLERYTVEQSRPAT----QGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPGTMIITLEETDIA-------SEDIVPVGVIAGGSVGSSILLLLLLFALIFYLYRQRKSS------------------------------------RRGVTL-KPDIKVETVNKETN-LEEEA----ASASTATRMVKAMYSFLPSVSLSPSTQPFKDDMDLKQDLQTETLEPKVEEYEAKDPTNGYYNVRATTHDEVRSSTRSLLYQEFRAPN-----PASVSASTGGPANIHPAP-----------TGRYEARPTSRMAHNT-YAHFNTIAR--ASQ-IQPPANPVSKTTDYPAERGLLESTNPLAFDSYAY---STTPQYRLGFAP----PLEAGPAYEMYPTGQGVGT-----SQDANVGKYPSSAQFPYSTPPTEYSQRHTQRMQTHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZQV3-1", "uniprot_id": "A0A8I5ZQV3_RAT", "id": "A0A8I5ZQV3-1", "name": "", "aln": "-----MRPFQLDLLFLCFFLFSQELGLQRRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAI-----QAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADN-AKPAASIIWLR--KGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVE-----------------------PQPVLEDNIVTFHCSAKANPAVTQYRWAKRGH-IIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAG--EREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESG---TSGRYTVETVNT-------EEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRS-----------TGGRPGISGRGTEQKARLRLPRRANLKGVVSAKNDIRVEIVHKEPASGREAE-----DHTTIKQLMMDRGE-------------FQQDSVLKQ-LEVLKEEEK-EFQNLKDPTNGYYSVNTFKE---HHSTPTISLSSCQPDLR----------------------------------------PTGKQRVPTGMSFTNIYSTL-SGQGRLYDYGQRFVLGMGSSSIELCER----EFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASK----------------ASASSS-HHSQSSSQNSDPSRPLQRRMQTHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BR86-1", "uniprot_id": "KIRR3_MOUSE", "id": "Q8BR86-1", "name": "Kin of IRRE-like protein 3", "aln": "-----MRPFQLDLLFLCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAI-----QAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADN-AKPAASIIWLR--KGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVE-----------------------PQPVLEDNIVTFHCSAKANPAVTQYRWAKRGH-IIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAG--EREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESG---TSGRYTVETVNT-------EEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQR------------------------------------NLKGVVSAKNDIRVEIVHKEPSSGREAE-----DHTTIKQLMMDRGE-------------FQQDSVLKQ-LEVLKEEEK-EFQNLKDPTNGYYSVNTFKE---HHSTPTISLSSCQPDLR----------------------------------------PTGKQRVPTGMSFTNIYSTL-SGQGRLYDYGQRFVLGMGSSSIELCER----EFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASK----------------ASASSS-HHSQSSSQNSDPSRPLQRRMQTHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZU9-1", "uniprot_id": "KIRR3_HUMAN", "id": "Q8IZU9-1", "name": "Kin of IRRE-like protein 3", "aln": "-----MKPFQLDLLFVCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAI-----QAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCHADN-AKPAASIIWLR--KGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVE-----------------------PQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQ-IIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAG--EREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESG---TSGRYTVETIST-------EEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQR------------------------------------NLKGVVSAKNDIRVEIVHKEPASGREGE-----EHSTIKQLMMDRGE-------------FQQDSVLKQ-LEVLKEEEK-EFQNLKDPTNGYYSVNTFKE---HHSTPTISLSSCQPDLR----------------------------------------PAGKQRVPTGMSFTNIYSTL-SGQGRLYDYGQRFVLGMGSSSIELCER----EFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASK----------------ASASSS-HHSQSSSQNSDPSRPLQRRMQTHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U2T1-1", "uniprot_id": "A0AB32U2T1_DANRE", "id": "A0AB32U2T1-1", "name": "", "aln": "---------MTLIISKRVSSLTQILTFPKWRTCGTA---------NLEPGGCVMFIQQPHDLVIVAGEPVTLPCTIIGYQGMVLWVKDGLALGVNRDLSGYPRYDVIGDHSKGEYHLLIERTELVDDGSFECQAI-----QVAGRSRPAQLTVLVPPDDPVIIGAPVVSLRAGDSLNLTCHANN-AKPAASIIWIR--NGEVINGAAYTKTLLRDGKRESTVSTLHISASNIESGQQITCRASNKAAPNGKEATVTIDIQHFPLVNLSVE-----------------------PQPVLEGNLVKFHCAAKANPPVTHYRWAKGGS-MITDATGDTYEVLVDHSFFTEPVSCEVTNALGSTNISRNVDVYFGPRLAAEPQSLQVDRGSDAVFSCAWIGNPSLTIVWMKRGHGVVLSNENTLTLKAVRQEDAGKYVCRAVVPRVGVG--EKEVMLTVNGPPSISSTQTQQALYGEKGQIKCFIRSTPPPDRIAWSWKETVLESG---TSGRYTVETVST-------EEGVISTLTMRNIVPTDFQTIYNCTAWNSFGSDTEIIRLKEQG------------SLRLAVIIGVAVGAFLALIVLIGTLGAFCCARLQRK--------DMHLVMSSLPVSLSSRQREISGTVKSENLKGVVSAKNDIRVEIVHKDHNAAREPE-----EHSNVKQMMMERAD-------------FQQESVLKQ-LEVLQEEER-ELQHIKDPTNGYYSVNTFKE---QPTPTISLTANQNAEVR-----------------------------------NPATATLGKHRVPTGMSYTNIYNTLGAGPNRLYDYSQRFVLGMGSSSIELCER----EFQRGSLSDSSSFQDTQCDSSVSSYSKQDGYVQFDKASK----------------ASVSSSSHYSQSSSQNSDLTRPLQKRMQTHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PG27-1", "uniprot_id": "A0A8M9PG27_DANRE", "id": "A0A8M9PG27-1", "name": "", "aln": "---------MPERSPPRRVKMILEVFLILWLTG---------------HGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAI-----QAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADN-AKPAASIIWIR--NGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVE-----------------------PQPVLEGNLVKFHCSAKANPPVTQYKWAKGGS-VIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAA--EKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESG---TSGRYTVETVST-------EDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGG--------SQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTEDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESE-----EHSGMKQLMIERGE-------------FQQESVLKQ-LEVLQEEEK-EYQHIKDPTNGYYSVNTFKE---HHGTPTTMAGNQTTELRR----------------------------------DPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCER----EFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSK----------------ASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6UWL6-1", "uniprot_id": "KIRR2_HUMAN", "id": "Q6UWL6-1", "name": "Kin of IRRE-like protein 2", "aln": "------------------MLRMRVPALLVLLFCFRG-----------RAGPSPHFLQQPEDLVVLLGEEARLPCALGAYWGLVQWTKSGLALGGQRDLPGWSRYWISGNAANGQHDLHIRPVELEDEASYECQAT-----QAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFR--DGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSAS-----------------------PHTVQEGEKVIFLCQATAQPPVTGYRWAKGGS-PVLGARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRRGGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAG---SQGRFLVETFPAPESRGGLGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASLGRR------------DLLPTVRIVAGVAAATTTLLMVITGVALCCWRHSKAS-------------------------------------ASFSEQKNLMRIPGSSDGSSSRGPEEEE---TGSREDRGPIVHTD--------------HSDLVLEE---------E-GTLETKDPTNGYYKVRGVSVS--LSLGEAPGGGLFLPPPS----------------------------------------PLGPPGTPTFYDFN-------------------PHLGMVPPCRLYRAR--------------AGYLTTPHPRAFTSYIKPTSFGPPDLAPG--------------------------TPPFPYAAFPTPSHPRLQTHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TSU7-1", "uniprot_id": "KIRR2_MOUSE", "id": "Q7TSU7-1", "name": "Kin of IRRE-like protein 2", "aln": "---------------------MLASALLVFLCCFKG-----------HAGSSPHFLQQPEDMVVLLGEEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQAS-----QAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFR--DGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAE-----------------------PQTVQEGEKVTFLCQATAQPPVTGYRWAKGGS-PVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPPVVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAG---SLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRR------------DLLPTVRIVAGAASAATSLLMVITGVVLCCWRHG-----------------------------------------SLSKQKNLVRIPGSSEGSSSRGPEEE----TGSSEDRGPIVHTD--------------HSDLVLEE---------K-EALETKDPTNGYYRVRGVSVS--LSLGEAPGGGLFLPPPS----------------------------------------PIGLPGTPTYYDFK-------------------PHLDLVPPCRLYRAR--------------AGYLTTPHPRAFTSYMKPTSFGPPELSSG--------------------------TPPFPYATLSPPSHQRLQTHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08180-1", "uniprot_id": "ICCR_DROME", "id": "Q08180-1", "name": "Irregular chiasm C-roughest protein", "aln": "------------------MLHTMQLLLLATIVGMVRSSP-------YTSYQNQRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVG-GKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFS-VSNETAGRYYCKANVP--GYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSE---SGHDYSILVDAVP-------GGVKSTLIIRDSQAYHYG-KYNCTVVNDYGNDVAEIQLQAKKS----------VSLLMTIVGGISVVAFLLVLTILVVVYIKCKKRTKLP---------------------------------------PADVISEHQITKNGGVSCKLEPGD-----RTSNYSDLKVDISG----------------GYVPYGDYSTHYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQHHTQT------------------------------------TTLPMTFLTNSSGGSLTGSIIGS----REIRQDNGLPSLQSTTASVVSSSP-----------NGSCSNQSTTAATTTTTHVVVPSSMALSVDPR-----------------------YSAIYGNPYLRSSNSSLLPPPTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* * : * . * * : * : * :..:.** ..* .: :* : *:: * * . * *:. ::**. : . ** * * *::**: . : . : . :: * : . .:* . : * . :. * : : . * : . . . . : * : . * : : : :.::: * * :. : * . * : * * *:* *:* . : . .: *.* * * :*.:: * ::: :.* : *.. .* .. . :.* .** :.* : *:.. * : * ** * *:* * :. : ::..* : : . ..::* : * . : *::. . : : .: *.* : . .: :**:. * * . * : : . . .: : : : :: : . :** : . : . . . . * *", "identical_positions": 80, "similar_positions": 159, "identity": "8.44%" }, { "cls_id": "homologset.agr.FB:FBgn0003292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2R1-1", "uniprot_id": "POMT1_MOUSE", "id": "Q8R2R1-1", "name": "Protein O-mannosyl-transferase 1", "aln": "------------------------------------------------------------------------------------------------------------------MGSHSTGLEETLGVLPSWLFCKMLRFLK----------------------RPLVVTVDINLNLVALTGLGLLTRLWQLSYPRAVVFDEVYYGQYISFYMKRIFFLDDSGPPFGHMLLALGGWLGGFDGNFLWNRIGAEYSSN-VPIWSLRLLPALAGALSVPMAYQIVLELHFSHGAAIGAALLMLIENALITQSRLMLLESILIFFNLLAVLSYLKFFNSQTHSPFSVHWWLWLLLTGVSCSCAVGIKYMGIFTYLLVLGIAAVHAWNLIGDQTLSN----------------------MRVLSHLLARIVALLVVPVFLYLLFFYVHLMLLYRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLKSVSGKPLPCWLHSHKNTYPMIYENGRGSSHQQQVTCYPFKDINNWWIVKDPGRHQLVVNNPPRPVRHGDIVQLVHGMTTRLLNTHDVAAPLSPHSQEVS--CYIDYNISMPAQNLWKLDIVNRESNRDTWKTILSEVRFVHVNTSAILKLS-GAHLPDWGFRQLEVVGEKLSPGYHESMVWNVEEHRYGKSHEQKERELELHSPTQLDISRN-LSFMARFSELQWKMLTLKNEDL-EHQYSSTPLEWLTLDTNIAYWLHPRTSAQIHLLGNIVIWTSASLATVVYTLLFFWYLLRRRRSICDLPEDAWSRWVLAGALCTGGWALNYLPFFLMERVLFLYHYLPALTFQILLLPIVLQHASDHLCRSQLQR-----------------NVFSALVVAWYSSACHVSNMLRPLTYGDTSLSPGELRALRWKDSWDILIRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99PR0-1", "uniprot_id": "POMT1_RAT", "id": "Q99PR0-1", "name": "Protein O-mannosyl-transferase 1", "aln": "------------------------------------------------------------------------------------------------------------------MGNRSMGREDTLGVLPSLLFCKMLRFLK----------------------RPLVVTIDINLNLVALTVLGLLTRLWQLSYPRAVVFDEVYYGQYISFYMKRVFFLDDSGPPFGHMLLALGGWLGGFDGNFLWNRIGAEYSSN-VPVWSLRLLPALAGALSVPMAYQIVLELHFSHCTAMGAALLMLIENALITQSRLMLLESILIFFNLLAVLSYLKFFNSQTHSPFSVHWWLWLMLTGVSCSCAVGIKYMGIFTYLLVLSIAAVHAWHLIGDQTLSN----------------------ICVLSHLLARAVALLVVPVFLYLLFFYVHLMLLYRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLKSVSGKPLPCWLHSHKNTYPMIYENGRGSSHQQQVTCYPFKDINNWWIVKDPGRHQLVVNNPPRPVRHGDIVQLVHGMTTRLLNTHDVAAPLSPHSQEVS--CYIDYNISMPAQNLWKLDIVNRESNQDTWKTILSEVRFVHVNTSAILKLS-GAHLPDWGFRQLEVVGEKLSLGPHESMVWNVEEHRYGRGHEQKERELELHSPTQHDISRN-LSFMARFSELQWKMLTLKNEDL-EHQYSSTPLEWLTLDTNIAYWLHPRTSAQIHLLGNIVIWTSASLATVAYTLLFFWYLLRRRRNICDLPEDAWSHWVLAGALCIGGWALNYLPFFLMERMLFLYHYLPALTFQILLLPIVMQHASDHLCRSQLQR-----------------NVFSALVVAWYSSACHVSNMLRPLTYGDTSLSPGELRALRWKDSWDILIRKY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6A1-1", "uniprot_id": "POMT1_HUMAN", "id": "Q9Y6A1-1", "name": "Protein O-mannosyl-transferase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MWGFLK----------------------RPVVVTADINLSLVALTGMGLLSRLWRLTYPRAVVFDEVYYGQYISFYMKQIFFLDDSGPPFGHMVLALGGYLGGFDGNFLWNRIGAEYSSN-VPVWSLRLLPALAGALSVPMAYQIVLELHFSHCAAMGAALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFNCQKHSPFSLSWWFWLTLTGVACSCAVGIKYMGVFTYVLVLGVAAVHAWHLLGDQTLSNVGADVQCCMRPACMGQMQMSQGVCVFCHLLARAVALLVIPVVLYLLFFYVHLILVFRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLRNVFGKPVPCWLHSHQDTYPMIYENGRGSSHQQQVTCYPFKDVNNWWIVKDPRRHQLVVSSPPRPVRHGDMVQLVHGMTTRSLNTHDVAAPLSPHSQEVS--CYIDYNISMPAQNLWRLEIVNRGSDTDVWKTILSEVRFVHVNTSAVLKLS-GAHLPDWGYRQLEIVGEKLSRGYHGSTVWNVEEHRYGASQEQRERERELHSPAQVDVSRN-LSFMARFSELQWRMLALRSDDS-EHKYSSSPLEWVTLDTNIAYWLHPRTSAQIHLLGNIVIWVSGSLALAIYALLSLWYLLRRRRNVHDLPQDAWLRWVLAGALCAGGWAVNYLPFFLMEKTLFLYHYLPALTFQILLLPVVLQHISDHLCRSQLQR-----------------SIFSALVVAWYSSACHVSNTLRPLTYGDKSLSPHELKALRWKDSWDILIRKH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QF89-1", "uniprot_id": "POMT1_DANRE", "id": "F1QF89-1", "name": "Protein O-mannosyl-transferase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MQCVK----------------------LPVSVTVEINVLLLAVTALALFTRLYGIHFPKAVVFDEVYYGQFLSLYMKQVFFIDESGPPFGHMILALGAYLGGFDGNFVWNRIGAEYPGN-VPVWSLRLIPALAGSFCVPLAYLVVVELGYSHFSALGACALLLMENSLIVQSRFMLLESVLIFFLLLAVLSYLRFHKARN----SFFKWFWLVICGVSCAFGIGVKYMGMFTYFLLLSLAAVHTWQLIGDQTLSHG----------------------KVMFQVLVRFLALVVLPVIMYLGFFYIHLTLLYRSGPHDQMMSSAFQASLEGGLARITQGQPLDVAFGSQVTLRTVSGKPVPCWLHSHKANYPIRYENGRGSSHQQQVTCYPFKDVNNWWIIKDPGRQSLVVSSPPKPVRHGDIIQLLHGMTTRYLNTHDVAAPMSPHSQEVS--GYIDFNVSMPAQNLWRVDIVNRESEKEIWKTILSEVRLVHVNTSAVLKLS-GASLPEWGFKQLEVVGDKIYKGYQQTGMWNVEEHRYGRSQEPKERELELKSPTHSDVNKN-LTFMAKFLELQWKMLTVKNEES-EHKYSSSPLEWITMDTNIAYWLHPSSNAQIHFIGNIVTWTTGNITLVVYCLLFLTYLLRRRRKVEDIPQDSWEQLVLAGVVCLGGWAVNYLPFFLMEKTLFLYHYLPALTFKILQIPIVTEHLYIHVLRSSAQQ-----------------KAFGGVILAVLCSVYMSYHSLSPLTYGQPALTSDKLAELRWRESWDILLRKR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTK2-1", "uniprot_id": "POMT1_DROME", "id": "Q9VTK2-1", "name": "Protein O-mannosyltransferase 1", "aln": "MSATYTNTITQRRKTAKVRQQQQHQWTGSDLSGESNERLHFRSRSTNSMQQHTAISNSPSPLCCNGARALTMLNCCVDVNCHLNAPLRGSVNRHTTPTPTPTATPTPVATPKQASPSPTSDRSRSLSRSPSPSRSRSLSCQKQIDKNSAGAASAEERKTANASSQPFTVNLRIDLFSWTLFLLAFGTRFYKLATPPHIVFDELHYGKYISMYMRNIFFFDQH-PPLGKQLIAGLVSLAGYDGNYTFTRIGEPYSPE-MPIFWFRFLPAMCGSLLAPAVYNLLLEAKLSRWSSALGGLLVVLDNSLLTQSRFVLMESMLLLATTVGIACLLRFQRSRLG---SLEWFFTGTAAAVCLGAAGTVKYVGFLALGLAFYLLCRHLWQLLYDAGLTDR----------------------QLWMHAISRLLIFVGIPLAVYLGVFYIHFKTLHRAGPHDSIMTSAFQASLDGGLASITKGQPLAVVHGSQITLRHTHGR--TCWLHSHAAVYPVRYPDKRGSSHQQQVTCYSFKDVNNWWLVKRPTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQCQEVS--CYIDYEIKMAGELLWRVEILNRDSEGDIWHAIKSEVRLVHVSTEASLKFS-GRQLPEWGFNQHEVVADRE-KAIHEDAIWNVEEHRYTQTEDHRERERQMLTAEMIPTKRTRISFWAKLLELQSKMLFQTKSVP-NHMYSSMPHEWPLMDKGIAYWLDSQSSAQIYLLGNILLWYTATMGILVYAGLLAFYAMRRQRLCFDISEQEWQRFVLAGDTFFMGYVMHYIPYFCVDRTLFLHNYLPAFVFKLLLLCFVVEHLDYLLRRFCTGRGVHLV------------RLYRLMLILWLVGVLSIFSKFIPFSYGARKMTLNEVRSLRWKDTWDFVLHKNHHLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46971-1", "uniprot_id": "PMT4_YEAST", "id": "P46971-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 4", "aln": "------------------------------------------------------------------------------------------------MSVPKKRNHGKLPPSTKDVDDPSLKYTKAAPKCEQVAEHWLLQPLP-------------------------EPESRYSFWVTIVTLLAFAARFYKIWYPKEVVFDEVHFGKFASYYLERSYFFDVH-PPFAKMMIAFIGWLCGYDGSFKFDEIGYSYETHPAPYIAYRSFNAILGTLTVPIMFNTLKELNFRAITCAFASLLVAIDTAHVTETRLILLDAILIISIAATMYCYVRFYKCQLRQPFTWSWYIWLHATGLSLSFVISTKYVGVMTYSAIGFAAVVNLWQLLDIKAGLSLR---------------------QFMRHFSKRLNGLVLIPFVIYLFWFWVHFTVLNTSGPGDAFMSAEFQETLK------DSPLSVDSKTVNYFDIITIKHQDTDAFLHSHLARYPQRYEDGRISSAGQQVTGYTHPDFNNQWEVLPPHGSDVGKG---QAVLLNQHIRLRHVATDTYLLAHDVASPFYPTNEEITTVTLEEGDGELYPETLFAFQPLKKSDEGHVLKSKTVSFRLFHVDTSVALWTHNDELLPDWGFQQQEINGNKK--VIDPSNNWVVDEIVN----------LDEVRKVYIPKVVKPLPFLKKWIETQKSMFEHNNKLSSEHPFASEPYSWPGSLSGVSFWTNGDEKKQIYFIGNIIGWWFQVISLAVFVGIIVADLITRHRGYYALNKMTREKLYGPLMFFFVSWCCHYFPFFLMARQKFLHHYLPAHLIACLFSGALWEVIFSDCKSLDLEKDEDISGASYERNPKVYVKPYTVFLVCVSCAVAWFFVYFSPLVYGDVSLSPSEVVSREWFDIELNFSK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :.: :*:: : * :****:::*:: * *:.. :*:* **:.: ::* * *:**.: : .** * . * * : *: *:: .* : : * :. . *: ::.: :.::*::*::::*:: : . ::* ..: : :: .:. . **:*.:: : *:*: . : * :: :*. :** *::*: : :** * :*:: ** :*. . .: . . : : .:**** ** * : * ** **** *.. *.** * : * .: . : .: ::* * * * :****:.: * :*:: : : .: : *: .: ::: .: . :: ..*:.**.*.. * . **:**:.* *: .:: . * *:* : . :.* : * * *: .. :* ::* * .* ..:::* . . **:::***: * : : : : *:* : : : . .: :*:*:* : : **::**** : * : : : : .:: .. : *: ** :: :: .* : . : ", "identical_positions": 126, "similar_positions": 220, "identity": "13.52%" }, { "cls_id": "homologset.agr.FB:FBgn0003295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAW6-1", "uniprot_id": "D4AAW6_RAT", "id": "D4AAW6-1", "name": "Rhomboid-related protein 3", "aln": "-------------------------MGEHPSPGPAVAACAEAERIEELEPEAEER---------LPAAPEDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLEARTRVALFLYNGVLLDQFVLQVTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALIC-------------------------------------------------MSMEFGRAVWLR-FHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNIFAYTLLDLKLPPPP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58873-1", "uniprot_id": "RHBL3_MOUSE", "id": "P58873-1", "name": "Rhomboid-related protein 3", "aln": "-------------------------MGEHPSPGPAVAACAEAERIEELEPEAEER---------LPAAPEDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLE----VALFLYNGVLLDQFVLQVTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALIC-------------------------------------------------MSMEFGRAVWLR-FHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNIFAYTLLDLKLPPAP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58872-1", "uniprot_id": "RHBL3_HUMAN", "id": "P58872-1", "name": "Rhomboid-related protein 3", "aln": "-------------------------MGEHPSPGPAVAACAEAERIEELEPEAEER---------LPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLE----VAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALIC-------------------------------------------------MSMEFGRAVWLR-FHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75783-1", "uniprot_id": "RHBL1_HUMAN", "id": "O75783-1", "name": "Rhomboid-related protein 1", "aln": "MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQ----IIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVC-------------------------------------------------MSSEVGRAVWLR-FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC82-1", "uniprot_id": "RHBL1_MOUSE", "id": "Q8VC82-1", "name": "Rhomboid-related protein 1", "aln": "-----------------------------------MDRSSLLQLIQE------------------------------QQLDPENTGFIGADTFAGLVHSHELPLDPTKLDMLVALAQSNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLSVYKRFVRYVAYEILPCEVDRRWYFYRHRTCPPPVFMASVTLAQ----IIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVC-------------------------------------------------MSSEVGRAVWLR-FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGADIPPPP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88779-1", "uniprot_id": "RHBL1_RAT", "id": "O88779-1", "name": "Rhomboid-related protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVC-------------------------------------------------MSSEVGRAVWLR-FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YY16-1", "uniprot_id": "A0A8M6YY16_DANRE", "id": "A0A8M6YY16-1", "name": "Rhomboid-related protein 1", "aln": "-----------------------------------MDRSSLFQLIQE-------------------------------QLDPEQTGFITVENFTSLAEHHELQLDPSKLEMLLALVQSNEHGHVCYQELIELLNSKRSSSFRRAIANGRRTLQREILLDETGLGVYKRFVRYVAYEILPCETDRRWYFHQNRLCPPPVFMAVITIVQ----IMVFMCYGVMLNKWVLQTYQPDFMKSPLVYHPGHRAQIWRFFSYMFMHVGLEQLGFNALLQLMIGVPLEMVHGILRISLLYMAGVIAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMKCPYKLLRMILALVC-------------------------------------------------MSSEVGRAVWLR-FSPPLPSSGPQPSFMAHLSGAVVGISMGLLILRSYEESLHKQCSWWVLIFSFVTFLLFAIFWNIFAYELLGVQIPPPP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0F8-1", "uniprot_id": "Q9W0F8_DROME", "id": "Q9W0F8-1", "name": "rhomboid protease", "aln": "---------------------------------MLLLSGAPSQ-----------------------------------GRRPKNRPLIGTVEEGEMPPSTVLQMPPAPLSSKSGLVLG-----VCCDQLMAVQPVQRASGAAATKSNSPDWGNHRAKHHEGSAAPFK--------------------------WIPPFFIILATLLE----VLVFLWVGADPPE-----------DSLLVYRPDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASGGVYALLAAQLASLLLNFG--QMRHGVIQLMAVILF-------------------------------------------------VFCDLGYALYSRELAMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQLDGGLRPRPLRWLALGVWCIFSAFGIAFNLVNTVTAQLLAEEEGQVIRQHLMNDLGMG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LN46-1", "uniprot_id": "A0ABK0LN46_RAT", "id": "A0ABK0LN46-1", "name": "Rhomboid-related protein 2", "aln": "-----------------------------------------------------------------------------------------------MAAAHEMEMESVNLNMEREGKEELEEE-KMRGDGEGKDFPRGRKVHRIVSKWMLPEPVRRTYLERAN------------------------------CLPPPLFIVLISLAE----LAVFIYYAVWKPQKQWITLDTGILESPLTYRPEKREEAWRFISYMLVHAGVQHIVGNLFMQLVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPALGIVRLLVIILIALVGSNELMEGELQDQQPAGQQSKARPGQREQNPAHCGDPRLHWASSLLVASDMGFALYRR---FFVPANGSPVSFAAHIAGGFAGMSVGYTVFSCFDKTLLKDPRFWISIAAYVACLLFAVFFNIFLSPAN----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AGA4-1", "uniprot_id": "RHBL2_MOUSE", "id": "A2AGA4-1", "name": "Rhomboid-related protein 2", "aln": "-----------------------------------------------------------------------------------------------MAVAHEMEMESVNLNMEREGKEEPEEE-KMKGNGEGKDFPRSRKVHRIVSKWMLPEPVRRTYLERAN------------------------------CLPPPLFIILISLAE----LAVFIYYAVWKPQKQWITLDTGILESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAFGIVRLLVIILI-------------------------------------------------VASDMGFALYRR---FFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX52-1", "uniprot_id": "RHBL2_HUMAN", "id": "Q9NX52-1", "name": "Rhomboid-related protein 2", "aln": "-----------------------------------------------------------------------------------------------MAAVHDLEMESMNLNMGREMKEELEEEEKMREDGGGKDRAKSKKVHRIVSKWMLPEKSRGTYLERAN------------------------------CFPPPVFIISISLAE----LAVFIYYAVWKPQKQWITLDTGILESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILI-------------------------------------------------IVLDMGFALYRR---FFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIFLSPAN----------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.. :: * *::.*:***:** * .::*:***:**** *: * :**.******* .. : .:::*: :.:: :: : :.* *:: * . *: **: * .*:::* :: : * *: : : ", "identical_positions": 41, "similar_positions": 51, "identity": "8.1%" }, { "cls_id": "homologset.agr.FB:FBgn0003300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13950-1", "uniprot_id": "RUNX2_HUMAN", "id": "Q13950-1", "name": "Runt-related transcription factor 2", "aln": "-------------------------------------------------------------------------------MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQE-------AAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDS-KPS--LFSDRLSDLGRIPHPSMRVG----VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAIT-DVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYP----ATFTYTP-PVTSGMS----LGMS---ATTHYHTYLPPPYPGSSQSQSGPFQTSSTPY-LYYGTSSGSYQFPMVP----GGDRSPSRMLPPCT---TTSNGSTLLNPNLPNQNDGVDADGSHSS--SPTVLNSSGRMDESVWRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08775-1", "uniprot_id": "RUNX2_MOUSE", "id": "Q08775-1", "name": "Runt-related transcription factor 2", "aln": "MLHSPHKQPQNHKCGANFLQEDCKKALAFKWLISAGHYQPPRPTESVSALTTVHAGIFKAASSIYNRGHKFYLEKKGGTMASNSLFSAVTPCQQSFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDS-KPS--LFSDRLSDLGRIPHPSMRVG----VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAIT-DVPRRISDDDTATSDFCLWPSSLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYP----ATFTYTP-PVTSGMS----LGMS---ATTHYHTYLPPPYPGSSQSQSGPFQTSSTPY-LYYGTSSASYQFPMVP----GGDRSPSRMVPPCT---TTSNGSTLLNPNLPNQNDGVDADGSHSS--SPTVLNSSGRMDESVWRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T797-1", "uniprot_id": "A0AB32T797_DANRE", "id": "A0AB32T797-1", "name": "Runt-related transcription factor", "aln": "-------------------------------------------------------------------------------MASNSLFSSVTPCQQNFFWDPSTSRRFSPPSSSLQP---------VAGKMSDAQPEPN------------------------------------AVVPRLR-PHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLEDPPKPP--LFSERLSELERLRQTTMRVA----VQTQSPRPSLNATPNSFNPQGQTQISDPRQVQSSPPWSYEQPYPPYLSQMTSPSIHSTTPLSSTRATGLPTIS-DVPRRLSG-----------TSELSPFSAD------PRQFERQFPSLSSLTDSRFPSPRMHYP----ATFTYTPTPVTSGMS----LGMS---TTTHYHTYLPPPYPGSTQNQSGPFQTSSTPY-LYYGASSGSYQFSMVP----GGDRSPSRMLPPCT---SASTGSTLINPNLPNQTDGGEADGSHSS--SPTVLNSSGRMDESVWRPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63046-1", "uniprot_id": "RUNX1_RAT", "id": "Q63046-1", "name": "Runt-related transcription factor 1", "aln": "---------------------------------------------------------------------------------------------MRIPVDASTSRRFTPPSTALSP-----------GKMSEALPLGAPD-------------------------------GGAALASKLR--SGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHS-TAFNPQPQSQMQDARQIQPSPPWSYDQSY-QYLGSITS-SVHPATPISPGRASGMTSLSAELSSRLST-----------APDLT-----------AFGDPRQFPTLPSISD-----PRMHYP----GAFTYSP-PVTSGIG----IGMSAMSSTSRYHTYLPPPYPGSSQAQAGPFQTGSPSYHLYYGTSAGSYQFSMV-----GGERSPPRILPPCT---NASTGAALLNPSLPSQSDVVETEGSHSN--SPTNMPP-ARLEEAVWRPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K7T0-1", "uniprot_id": "A0A0G2K7T0_RAT", "id": "A0A0G2K7T0-1", "name": "Runt-related transcription factor", "aln": "-------------------------------------------------------------------------------MASNSIFDSFPNYTPTFIRDPSTSRRFTPPSTAFPCGG------GGGGKMGENSGALSAQ---------------------------------AAAGPGGRTRPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKIEDQTKAF----PDRFGDLR------MRVTP----STPSPRGSLSTT-SHFSSQAQTPIQGSSDLN---------------------------PFSDPR----------------------------------------------QFDRSFPTLQSLTESRFPDPRMHYPGAMSAAFPYSATPSGTSLGGLSVAGMP--ASSRFHHTYLPPPYPGAPQSQSGPFQANPAPYHLFYGTSSGSYQFSMAAAG--GGERSPTRMLTSCP-TGASVSAGNLMNPSLG-QADGVEADGSHSN--SPTALSTPGRMDEAVWRPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64131-1", "uniprot_id": "RUNX3_MOUSE", "id": "Q64131-1", "name": "Runt-related transcription factor 3", "aln": "-------------------------------------------------------------------------------MRIP--------------VDPSTSRRFTPPSTAFPCGG------GGGGKMGENSGALSAQ---------------------------------ATAGPGGRTRPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKIEDQTKAF----PDRFGDLR------MRVTP----STPSPRGSLSTT-SHFSSQAQTPIQGSSDLN---------------------------PFSDPR----------------------------------------------QFDRSFPTLQSLTESRFPDPRMHYPGAMSAAFPYSATPSGTSLGSLSVAGMP--ASSRFHHTYLPPPYPGAPQSQSGPFQANPAPYHLFYGASSGSYQFSMAAAG--GGERSPTRMLTSCP-SGASVSAGNLMNPSLG-QADGVEADGSHSN--SPTALSTPGRMDEAVWRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13761-1", "uniprot_id": "RUNX3_HUMAN", "id": "Q13761-1", "name": "Runt-related transcription factor 3", "aln": "-------------------------------------------------------------------------------MRIP--------------VDPSTSRRFTPPSPAFPCGG------GGG-KMGENSGALSAQ---------------------------------AAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKPF----PDRFGDLERL---RMRVTP----STPSPRGSLSTT-SHFSSQPQTPIQGTSELN---------------------------PFSDPR----------------------------------------------QFDRSFPTLPTLTESRFPDPRMHYPGAMSAAFPYSATPSGTSISSLSVAGMP--ATSRFHHTYLPPPYPGAPQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLASCTSSAASVAAGNLMNPSLGGQSDGVEADGSHSN--SPTALSTPGRMDEAVWRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22814-1", "uniprot_id": "RUNT_DROME", "id": "P22814-1", "name": "Segmentation protein Runt", "aln": "-----------------------------------------------MHLPAGPTMVANNTQVLAAAAAAAAAAAAAVAQGPGPQQSSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQN----------------------------------SAKMPSSMTDMFASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRSKQSYGYPHPGAFN-PFMLNPAWLDAAYMTYGYADYFRHQAAAQAAQVHHPALAKSSASSVSPNPNPSVATSSSSAVQPSEYPHPAAAVAAAAGQPAAMMPSPPGAAPATPY-------------------------------------AIPQFPFNHVAAAAAAKAATPHAFHP----YNFAAAAGLRARNAALHHQSEPVHVSPASSRPSSSSPTQQHVLLKLNTSIETSSIHEQSASDGDSDDEQIDVVKS---EFDLDKSLDVAPLR-MRCDLKAPSAMKPLYHESGPGAVANSRQPSPETTTKIKSAAVQQKTVWRPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: * :.. .: . . : :: ::: :: .**.:*.**.:***.**.***.**:** ****:**.:*****:*:: .******..****.::.******:*********************: * * *:*:* :***:********* ::. . . . * . . .. : ... : .. :. * : : : *: .:* *. :. . . .: : .*. .:::.. . .: . *: :. : . . :.. . ::* . ::. :.. :.* : . . :::*****", "identical_positions": 98, "similar_positions": 119, "identity": "15.38%" }, { "cls_id": "homologset.agr.FB:FBgn0003301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LB28-1", "uniprot_id": "A0ABK0LB28_RAT", "id": "A0ABK0LB28-1", "name": "Adenylate cyclase type 1", "aln": "MAGAPRGQGGGGG-AGEPGGAERAAGPGGRRGFRACGEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCILFLALFVVTNVRSLQVSQLQQVGQLALFFSLTFALLCCPFALGGPARSSAGGAMGSAVAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTAALVP--AKRPRLWRTLGANALLFFGVNMYGVFVRILTERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNTFLRTHNIETFFIVP-SHRRKIFPG---LILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMT--------------------------------CEDDD---------KRRALR---------------------------------------------------------TASEKLRNRSSFSTN---------------------VVYTTPGTRVNRYISRLLEARQTELEMAD-LNFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILATLFGLIYLLVIPQSVAVLLLLVFSICFLVACTLYLHITRVQCFPG--CLTIQIRTALCVFIVVLIYSVAQGCVVSCLPWAWSSHSNSSLVVLAAGGRRTVLPALPCESAHHGLLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTKVGG-----GALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRN-MDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAK--KSISSHLSTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLNRCSYQFVCRGKVSVKGKGEMLTYFLEG-----------------------------------------------------------------------------------------------------------------RTDGSSSHSRSLRLERRMFPYGRGGGGQARRP--------------------------------PLCPAAGPPIK---------------------------------------PGLSPAPTSQYLSSTAAGKEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88444-1", "uniprot_id": "ADCY1_MOUSE", "id": "O88444-1", "name": "Adenylate cyclase type 1", "aln": "MAGAPRGQGGGGG-AGEPGGAERAAGPGGRRGFRACGEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCILFLALFVVTNVRSLQVSQLQQVGQLALFFSLTFALLCCPFALGGPARSSAGGAMGSTVAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTAALVP--AKRPRLWRTLGANALLFFGVNMYGVFVRILTERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNTFLRTHNIETFFIVP-SHRRKIFPG---LILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMT--------------------------------CEDDD---------KRRALR---------------------------------------------------------TASEKLRNRSSFSTN---------------------VVYTTPGTRVNRYISRLLEARQTELEMAD-LNFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILAALFGLIYLLVIPQSVAVLLLLVFSICFLVACTLYLHITRVQCFPG--CLTIQIRTALCVFIVVLIYSVAQGCVVGCLPWAWSSQSNSSLVVLAAGGRRTVLPALPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTKVGG-----GALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRN-MDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAK--KSISSHLCTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKRCSYQFVCRGKVSVKGKGEMLTYFLEG-----------------------------------------------------------------------------------------------------------------RTDGNSSHGRTFRLERRMCPYGRGGG-QARRP--------------------------------PLCPAAGPPVR---------------------------------------PGLPPAPTSQYLSSTAAGKEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08828-1", "uniprot_id": "ADCY1_HUMAN", "id": "Q08828-1", "name": "Adenylate cyclase type 1", "aln": "MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVP--AKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVP-SHRRKIFPG---LILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMT--------------------------------CEDDD---------KRRALR---------------------------------------------------------TASEKLRNRSSFSTN---------------------VVYTTPGTRVNRYISRLLEARQTELEMAD-LNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPG--CLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGG-----GAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRN-MDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAK--KSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEG-----------------------------------------------------------------------------------------------------------------RTDGNGSQIRSLGLDRKMCPFGRAGL-QGRRP--------------------------------PVCPMPGVSVR---------------------------------------AGLPPHSPGQYLPSAAAGKEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32870-1", "uniprot_id": "CYA1_DROME", "id": "P32870-1", "name": "Adenylate cyclase 1", "aln": "--------------------MDHAVKATRGRPLNTL--RFENDELECLYQRYTLKLQRFSVLGVVALVFVLCGVMAALSLTFNN--AATFHNIFNAIVCGLFAVVLVLLQCSVIKDHHLPTLCYGILLFTASICVVSMP-TLG-----SVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYKIFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDILSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPPHRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQLLHT-IKFSEPVPFSNIATGSFPSAASALGGGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGVDSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFLSQAINARSVDCDKSEHVDRLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCS-GNGTTSFQNDSHRKCSLPQYVSLSAAFAFLS-------VSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFLCDSGNKSLNGEVRNAMSLPQSLHAPDYYMKVSQFPENRVNTDTYSKKENGHLYAGNGVEEQQLLLQHQHKQHDPLPLPAPPPPVHHHLHQQQQQRLNSKLQKQPIFMANGGLPNIRENGNGHNGEHQQQQQQQQQHQQQQQQQQQHGGFMVATTTPPAAVAVPLQPQHHQLQFQHPHQHPLPSAVSVPVQHQILLHHQLQLQHQPVPSVMLREFNIIENPTSGGRHQQMEQLPPHHGSLDLSGMGMGVGAGVLGSDCFMMPRRDRERTYVPPLNQHGHHPPHHLHSNLNLNQSQHPPSFTSLGYGQCRESEPLLHASSVAPVAKIMPMQHAPKYEPPRYTSPHTMLSQQHQQQQQQQHQHQQPQSQSAQDQQTHPAQDPHPLQRQYAMYSQQPQLPPKPVLRTYMKPLPKLPTDLEESRDMSSTDDLSSRPHSPSMSSSDESYSKTTEGEGEGDEDSPRMVNGGHLHHRNGYHLPAGGLVNPLQWLYPCDIQVDPTSPVVDMAHLHDFELSSTTESQGHHTNSNTTSNTQHKGDSCNSFDFQKAAVGTAAGAAIATKSPFERELQRLLNESSRARCLATATTTAGAISTTDQTASNGSRELSYSLSNGKLSSANGHGVGGSGSGSGSGSGSGSAVGNGSGGSGSSNGNLSGGSGSNSNSGNNNSSHHKTEQQQNMDHEHLAGGKLLGSNSFMIAKHPVGLEAIKEITRNKNPSESSQMQTSDTESCEILHENRNQMHVLAMLEMHTAKELNGSHAHHGQHHQQPQRTHRQRPRSKELQYSHESLDGLDGAVQSQSQQRHQRYHHHHHHQQRQQQQQRYNHVQEQEERDDTEDNLADEEFEDDEVGRDVRQKRLQKSELNHKRSEVATEAGNHHDDEVEEEDDDDDEEEDHRNGGREAAPLTNGSMRGLEANVINDELKYGATHLNHQSMDSNPLESQSEWSDDDCREEATGGAESTGYITDEPGLENISLLNEAGLTDAEGALSDVNSLYNAPDVDDTSVSSRASSRLLSLDSLSGLYDCDLDSKHELAIVNASHKISSKFGQPLSPAQQQHQQQQQQQQQQQQQHHQQQLQQNPQHTQAQSHLAPVQFQSAEELRE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*. . * :.: .* ***.*:: ***:*:: :.* .:*:: :*.*.:* .* *. : : :.: * ** .::*: : :: :* : *:*: ::.::. * :** *. . . :****:::*.*::**::*:: *:.**:.:.: *: :*. : * * :. * ** ::*.***: *:.*.*: **:**::**::*.** .**.::***** ****:*:**::***:**:*:*.* **:****:*:************* *:***:*****:*******:**:** :*** ***************.:*:.***:*.*********:*::*.***:* ******:****************:*********** **:.* **:**:*::** .*.*:****.*:*.**.::*: *.::****** .**** : : * * . :::.*:.*. :::**:* *. :****: * ** :. .*:.:* *** * : .* ..: * .****::*: ::**..: : :: :: :**:::: : *::**: * **:*: :*:* * . : : :*::: :***::*.: :: * : * .*:: : . ::.:* .: :* *:*****.* *. *:. .* *.: . . :: ** . *: ..:*. :::*:*:. : * :*: *: * * *.:*** . .* .: * :* :: :*.* *: ***:** **.:*:.:*: :: .*:***.******** *** :: ** *:**:***::***:***:****:** *:**.: *:****************:.:* ::.::****:******.*** * :.: :*: *: :* ::. * . *:*** :***:*:******:***********:********************* * ***:** * . :.* ***.:.*****:*:**** . * :*.. : . ::: . : * :: *: . . .:: *.* . *.. . * * ", "identical_positions": 472, "similar_positions": 351, "identity": "20.64%" }, { "cls_id": "homologset.agr.FB:FBgn0003308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5QE79-1", "uniprot_id": "AOXD_RAT", "id": "Q5QE79-1", "name": "Aldehyde oxidase 4", "aln": "MP---SSSDELIFFVNGKKVIEKNPVPEMNLLFYVRKVLHLTGTKYSCGGGGCGACTVMISRYNPESKKIYHYPATACLVPVCSLHGAAVTTVEGVGSIKRRIHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPTPDQITEALGGNLCRCTGYRPIVESGKTFSPESSVCQMKGS-GKCCMDLDEGCSESTKE--RMCTKLYNEDEFQPLDPSQEPIFPPELIRMAEDPHKRRLTFQGERTIWIMPVTLNGLLELKASYPEAPLVMGNTAVGPGMKFNNEFHPVFISPLGLPELNLVDTANSGGVTIGARHSLAQMKDILHSLTLEQPKEKTKTHQALLKHLRTLAGPQIRNMATLGGHVVSRPDFSDLNPILAAGNATINVIS---KEGQ-RQIPLNGPFLERLPEASLKPEEVALSVFIPYSGQWQYVSGLRLAQRQENAFAIVNAGMSVEFEEGTNTIKDLQMLFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLEEIRIPPDAEGGMVEYRRTLIISLLFKFYLKVRRWLS--------EMDPQKFPDIPEKFVSALDDLPIETPQGIQMFQCVDPNQPEQDPVGHPIMHQSGIKHATGEAKFVDDMPRINQELCLTVVTSTRAHAKITSIDVSEALAYPGVVDVITAEDVPGDN-NHS----GEIFYAQNEVICVGQIICTVAADTYIHAKEAAKRVKITYDDIEPAIITIEQALEHNSFLSSEKKIE-QGNVDYAFKHVDHIIEGEIHVEGQEHFYMETQTILAIPQTEDKEMVLHVGTQFPTHVQEYVSAALKVPRNRIACQMKRTGGAFGGKVTKPALLGAVCAVAAHKTGRPIRFILDRSNDMLITAGRHPLLGKYKIGFMNNGKIKAADVEYYTNGGCTPDESEMVIEFIVLKSENAYHIPNFRCRGRACKTNLPSNTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEIREINMYKQISKTAYKQTFNPEPLRRCWKECLQKSSFFARKQAAEEFNKNNYWKKKGLAVVPMKFSVAVPMAFYNQAAALVHIFLDGSVLLTHGGCELGQGLHTKMIQVASRELNIPKSYVHLVETSTVTVPNAVFTAGSMGADINGKAVQNACQTLLDRLQPIIKKNPKGKWEEWVKKAFEESISLSATGYFKGYQTNMDWEKEE-GDPYPYYVYGAACSEVEVDCLTGAHKLLRTDIFMDAAFSINPALDIGQVEGAFIQGMGFYTIEELKYSPKGVLYSRGPDDYKIPTVTEIPEEFYVTMVR-SRNPIAIYSSKGLGEAGMFLGSSVLFAIYDAVTTARK---ERGLSDIFPLNSPATPEVIRMACKDQFTDMIPRDDPSTFTPWSIHVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TYQ9-1", "uniprot_id": "AOXD_MOUSE", "id": "Q3TYQ9-1", "name": "Aldehyde oxidase 4", "aln": "MPS-VSESDELIFFVNGKKVIEKNPDPEKNLLFYTRKVLNLTGTKYSCGTGGCGACTVMVSRYNPKTRKIHHYPATACLVPICWLHGAAITTVEGVGSIKKRVHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPTPDQITEALGGNLCRCTGYRPIVESGKTFSQKSTVCQMKGS-GKCCMDPDEKCLESREK--KMCTKLYNEDEFQPFDPSQEPIFPPELIRMAEDPNKRRLTFQGKRTTWIIPVTLNDLLELKASYPEAPLVMGNTTVGPGIKFNDEFYPVFISPLGVPELNLMDTTNNG-VTIGAGYSLAQLKDTLDFLVSEQPKEKTKTFHALQKHLRTLAGPQIRNMATLGGHTASRPNFSDLNPILAAGNATINVVS---REGKDRQLPLNGPFLEKLPEADLKPEEVILSIFIPYTAQWQFVSGLRLAQRQENAFAIVNAGMSVEFEEGTNTIKDLKMFFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLQEIRIPPDAEGGMVEYRRTLIISLLFKFYLKVQRWLN--------EMDPQKFPDIPGKFVSALDDFPIETPQGIQMFQCVDPKQPQKDPVGHPIMHQSGIKHATGEAIFIDDMPPIDQELCLAVVTSTRAHAKITSLDVSEALACPGVVDVITAEDVPGEN-DHN----GEILYAQSEVICVGQIICTVAADTYIHAKEAAKRVKIAYDDIEPTIITIEEALEHNSFLSPEKKIE-QGNVDYAFKHVDQIVEGEIHVEGQEHFYMETQTILAIPQTEDKEMVLHLGTQFPTHVQEFVSAALNVPRSRIACHMKRAGGAFGGKVTKPALLGAVCAVAANKTGRPIRFILERSDDMLITAGRHPLLGKYKIGFMNNGEIRAADVEYYTNGGCTPDESELVIEFVVLKSENTYHIPNFRCRGRACKTNLPSNTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEVREINMYKKTSKTAYKQTFNPEPLRRCWKECLEKSSFFARKKAAEEFNGNNYWKKRGLAVVPMKFSVAVPIAFYNQAAALVHIFLDGSVLLTHGGCELGQGLHTKMIQVASRELNVPKSYVHFSETSTTTVPNSAFTAGSMGADINGKAVQNACQILMDRLRPIIRKNPKGKWEEWIKMAFEESISLSATGYFKGYQTNMDWKKEE-GDPYPYYVYGAACSEVEVDCLTGAHKLLRTDIFVDAAFSINPALDIGQVEGAFIQGMGFYTTEELKYSPKGVLYSRGPEDYKIPTITEIPEEFYVTLVH-SRNPIAIYSSKGLGEAGMFLGSSVLFAIYDAVTTARK---ERGLSDIFPLNSPATPEVIRMACTDQFTEMIPRDDPSTFTPWSIHVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3X982-1", "uniprot_id": "AOXC_MOUSE", "id": "G3X982-1", "name": "Aldehyde oxidase 3", "aln": "MSP-SKESDELIFFVNGKKVTERNADPEVNLLFYLRKVIRLTGTKYGCGGGDCGACTVMISRYDPISKRISHFSATACLVPICSLHGAAVTTVEGIGSTKTRIHPVQERIAKGHGTQCGFCTPGMVMSIYTLLRNHPEPSTEQIMETLGGNLCRCTGYRPIVESAKSFCPSSTCCQMNGE-GKCCLD-EEKNEPERKN--SVCTKLYEKKEFQPLDPTQELIFPPELMRMAEESQNTVLTFRGERTTWIAPGTLNDLLELKMKHPSAPLVIGNTYLGLHMKFTDVSYPIIISPARILELFVVTNTKQG-LTLGAGLSLTQVKNVLSDVVSRLPKEKTQIYCALLKQLKTLAGQQIRNVASLGGHIISRLPTSDLNPILGIGNCILNVAS---TEGI-QQIPLNDHFLAGVPDAILKPEQVLISVFVPRSSKWEFVSAFRQAPRQQNAFATVNAGMKVVFKEDTNTITDLGILYGGIGATVISADKSCRQLIGRCWDEEMLDDAGKMICEEVSLLMAAPGGMEEYRKTLAISFLFMFYLDVLKQLK--------TRDPHKYPDISQKLLHILEDFPLTMPYGMQSFQDVDFQQPLQDPIGRPIMHQSGIKHATGEAVFCDDMSVLPGELFLAVVTSSKSHAKIISLDASEALASLGVVDVVTARDVPGDN-GRE----EESLYAQDEVICVGQIVCAVAADSYAHAQQAAKKVKIVYQDIEPMIVTVQDALQYESFIGPERKLE-QGNVEEAFQCADQILEGEVHLGGQEHFYMETQSVRVVPKGEDKEMDIYVSSQDAAFTQEMVARTLGIPKNRINCHVKRVGGAFGGKASKPGLLASVAAVAAQKTGRPIRFILERRDDMLITGGRHPLLGKYKIGFMNNGKIKAADIQLYINGGCTPDDSELVIEYALLKLENAYKIPNLRVRGRVCKTNLPSNTAFRGFGFPQGAFVTETCMSAVAAKCRLPPEKVRELNMYRTIDRTIHNQEFDPTNLLQCWEACVENSSYYNRKKAVDEFNQQRFWKKRGIAIIPMKFSVGFPKTFYYQAAALVQIYTDGSVLVAHGGVELGQGINTKMIQVASRELKIPMSYIHLDEMSTVTVPNTVTTGASTGADVNGRAVQNACQILMKRLEPIIKQNPSGTWEEWVKEAFVQSISLSATGYFRGYQADMDWEKGE-GDIFPYFVFGAACSEVEIDCLTGAHKNIRTDIVMDGSFSINPAVDIGQIEGAFVQGLGLYTLEELKYSPEGVLYTRGPHQYKIASVTDIPEEFHVSLLTPTPNPKAIYSSKGLGEAGTFLGCSVFFAIAAAVAAARE---ERGLSPIWAINSPATAEVIRMACEDQFTNLVPQTDSKCCKPWSIPVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SGK3-1", "uniprot_id": "AOXB_MOUSE", "id": "Q5SGK3-1", "name": "Aldehyde oxidase 2", "aln": "MPCPAQISDDLEFFVNGRKVTEKNVDPEVTLLAFLRKNLCLTGTKDACGTGGCGACTVMVSQHDPVCKKTRHFSVMACLVPLCSLHGAAVTTVEGVGSIKTRLHPVQERIAKSHGTQCGFCTPGMVMSIYTLLRNHPQPSEEQLMEALGGNLCRCTGYRPILESGRTFCMEPDGCPQKGT-GQCCLDQKESDSSGSKS--DICTKLFVKDEFQPLDPTQELIFPPELLRMAENPEKQTLTFYGERITWIAPGTLQELLVLKAKYPEAPLISGNTALGPAMKSQGHFYPVLLSPARIPDLRMVTKTSGG-LTIGACCSLAQVKDILAESISELPQEKTQTYRALLKHLRSLAGQQIRNMASLGGHVISRHCYSDLNPILSVGNTTLNLLS---EEGP-RQIPLSGHFLAGLASADLKPEEILGSVYIPHSQKREFVSAFRQAQCHQNALPDVNAGMRVLFREGTDVIEELSIAYGGVGPTTVSAQRSCQQLLGRRWNALMLDEACRLLLDEVSLPGSALGGKVEFRRTLIVSLFFKFYLEVLQELKADQKLPPESTDSQRYPEIADRFLSSLGDFQVTLPRGVQTYQRVDSHQPLQDPVGRPIMHLSGLKHATGEAVFCDDIPRVDKELFMALVTSTRAHARIISIDSSEVLDLPGVVDVITAEDIPGNN-GEE----DDKLLAVDKVLCVGQVICAVVAETDVQAKRATEKIKITYEDLKPVIFTIEDAIKHNSFLCPEKKLE-QGNIEEAFENVDQVAEGTVHVGGQEHFYMETQRVLVIPKTEDKELDMYVSTQDPAHVQKTVSSTLNIPISRITCHVKRVGGGFGGKVGRPAVFGAIAAVGAVKTGHPIRLVLDREDDMLITGGRHPLFAKYKVGFMNSGRIKALDIECYINGGCTLDDSELVTEFLVLKLENAYKIRNLRLRGRACMTNLPSNTAFRGFGFPQGALVTESCITAVAAKCGLPPEKIREKNMYKTVDKTIYKQAFNPDPLIRCWNECLDKSSFHIRRTRVDEFNKKSYWKKRGIAIVPMKFSVGFAATSYHQAAALVHIYTDGSVLVAHGGNELGQGIHTKMLQVASRELKIPLSYLHICETSTTTVPNTIATAASVGADVNGRAVQNACQILLKRLEPVIKKNPEGTWRDWIEAAFEKRISLSATGYFRGYKAFMDWEKGE-GDPFPYYVYGAACSEVEIDCLTGAHKKIRTDIVMDACCSLNPAIDIGQIEGAFIQGMGLYTTEELLYSPEGVLYSRSPDKYKIPTVTDVPEQFNVSLLPSSQTPLTLYSSKGLGESGMFLGSSVFFAIVDAVAAARR---QRDIAEDFTVKSPATPEWVRMACADRFTDMIPRDDPKTFKPWSIPIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QE78-1", "uniprot_id": "AOXB_RAT", "id": "Q5QE78-1", "name": "Aldehyde oxidase 2", "aln": "MPCPSQSSDELEFFVNGKKVTEKNVDPEVTLLAFLRKNLRLTGTKYACGTGSCGACTVMVSQHDPVCKKTRHFSVMACLVPLCSLHGAAVTTVEGVGSIKTRLHPVQERLAKSHGTQCGFCSPGMVMSMYALLRNHPQPSEEQLLEALGGNLCRCTGYRPILESGRTFCMESDGCLQKGT-GQCCLDQKEGDSSGSKS--DICTELFVKDEFQPLDPTQELIFPPELLRMAENPEKQTLTFYGERITWIAPGTLQELLVLKAKYPEAPLISGNTALGPAMKSQGHFYPVLLSPARIPDLRMVTKTSGG-LTIGACCSLAQVKDVLAESISELPEEKTQTYRALLKHLRSLAGQQIRNMASLGGHVISRHYYSDLNPILSVGNATLNLLS---EEGL-RQIPLNGHFLAGLANEDLKPEEILGSVYIPHSQKREFVSAFRQAQCHQNALPDVNAGMRVLFKEGTDIIEELSIAYGGVGPTTVSAHRSCQQLLGRRWNALLLDEACRLLLDEVSLPGSAVGGKVEFRRTLIVSFFFKFYLEVLQELKADKRLLPESTDSQRYPEIADGSRSSLGDFQVTLPQGVQTYQRVNSHQPLQDPVGRPIMHLSGLKHATGEAVFCDDIPRVDKELFMALVTSTRAHARIISIDSSEVLDLPGVVDVITAEDIPGNN-GEE----DDKLLAVDKVLCVGQVVCAVVAETDVQAKRATKKIKITYEDLKPVLFTIEDAIQHNSFLCPEKKLE-QGNMEEAFENVDQIVEGKVHVGGQEHFYMETQRVLVIPKTEDKELDMYVSTQDPAHVQKTVSSALNIPLSRITCHVKRVGGGFGGKVGRPAVFGAIAAVGAVKTGRPIRLVLDREDDMLITGGRHPLFAKYKVGFMNSGRIKALDIECYINGGCTLDDSELVTEFLVLKLENAYKIRNLRLRGRACMTNLPSNTAFRGFGFPQGALVTESCITAVAAKCGLPPEKIREKNMYKTVDKTIYKQAFNPEPLIRCWNECLDKSSFAIRRTRVDEFNKKSYWRKRGIAVVPMKFSVGFAATSYHQAAALVHIYTDGSVLVAHGGNELGQGIHTKMLQVASRELKIPMSYLHTSETCTAAVPNTIATAASVGADVNGRAVQNACQILLKRLEPVIKKNPEGTWRDWIEAAFEQRISLSATGYNRGYKAFMDWEKGE-GDPFPYYVYGAACSEVEIDCLTGAHKKMRTDIVMDACCSLNPAIDVGQIEGAFIQGMGLYTTEDVHYSPEGVLYSRSPDKYKIPTVTDVPEQFNVSLLPSSQTPLTIYSSKGLGESGMFLGSSVFFAIADAVAAARR---QRDIAEDFTVKSPATPERVRMACADRFTDMIPRDDPKTFKPWSIPIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0U5-1", "uniprot_id": "AOXA_RAT", "id": "Q9Z0U5-1", "name": "Aldehyde oxidase 1", "aln": "----MD-PPQLLFYVNGQKVVENNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKSIRHHPVNACLTPICSLYGTAVTTVEGIGNTRTRLHPVQERIAKCHSTQCGFCTPGMVMSMYALLRNHPEPSLDQLTDALGGNLCRCTGYRPIIDACKTFCRASGCCESKEN-GVCCLDQGINGSAEFQEGDETSPELFSEKEFQPLDPTQELIFPPELMRIAEKQPPKTRVFYSNRMTWISPVTLEELVEAKFKYPGAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELSIINQTGDG-LTLGAGLSLDQVKDILTDVVQKLPEETTQTYRALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLS---KDGK-RQIPLSEQFLRKCPDSDLKPQEVLVSVNIPCSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFREGGGVIKELSILYGGVGPTTIGAKNSCQKLIGRPWNEEMLDTACRLVLDEVTLAGSAPGGKVEFKRTLIISFLFKFYLEVLQGLK--------REDPGHYPSLTNNYESALEDLHSKHHWRTLTHQNVDSMQLPQDPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQDAT-TFG----TETLLATDKVHCVGQLVCAVIADSETRAKQAAKHVKVVYRDLEPLILTIEEAIQHKSFFESERKLE-CGNVDEAFKIADQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKHIQDIVAATLKLSVNKVMCHVRRVGGAFGGKVGKTSIMAAITAFAASKHGRAVRCTLERGEDMLITGGRHPYLGKYKVGFMRDGRIVALDVEHYCNGGSSLDESLWVIEMGLLKMDNAYKFPNLRCRGWACRTNLPSHTALRGFGFPQAGLVTEACVTEVAIRCGLSPEQVRTINMYKQIDNTHYKQEFSAKTLFECWRECMAKCSYSERKTAVGKFNAENSWKKRGMAVIPLKFPVGVGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQVVSRELKMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDWAQTAFDQSVSLSAVGYFRGYESNINWEKGE-GHPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGHSINPALDIGQVEGAFIQGMGLYTIEELSYSPQGILYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVRAARQ---ERGISGPWKLTSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNIPV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54754-1", "uniprot_id": "AOXA_MOUSE", "id": "O54754-1", "name": "Aldehyde oxidase 1", "aln": "----MD-PIQLLFYVNGQKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKAIRHHPVNACLTPICSLHGTAVTTVEGLGNTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCKASACCQSKEN-GVCCLDQEINGLAESQEEDKTSPELFSEEEFLPLDPTQELIFPPELMRIAEKQPPKTRVFYGERVTWISPVTLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDG-LTLGAGLSLDQVKDILADIVQKLPEEKTQTYRALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLS---KDGE-RRIPLSEEFLRKCPEADLKPQEVLVSVNIPWSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFREGGGVIEELSILYGGVGSTIISAKNSCQRLIGRPWNEGMLDTRCRLVLDEVTLAASAPGGKVEFKRTLIISFLFKFYLEVSQGLK--------REDPGHSPSLAGNHESALDDLHSKHPWRTLTHQNVDPAQLPQDPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQEAN-TFG----TETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLAPLILTIEEAIQHKSFFKSERKLE-CGNVDEAFKIVDQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGGKVGKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNEGRILALDVEHYCNGGCSLDESLWVIEMGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMYKHVDTTHYKQEFSAKALSECWRECMAKCSYFERKAAIGKFNAENSWKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDWAQTAFDQSISLSAVGYFRGYESNIDWEKGE-GHPFEYFVFGAACSEVEINCLTGDHKNIRTNIVMDVGHSINPALDIGQVEGAFIQGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVKAARQ---ERGISGPWKLNSPLTPEKIRMACEDKFTKMIPRDEPGSYVPCNIPV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06278-1", "uniprot_id": "AOXA_HUMAN", "id": "Q06278-1", "name": "Aldehyde oxidase", "aln": "----MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPITKRIRHHPANACLIPICSLYGAAVTTVEGIGSTHTRIHPVQERIAKCHGTQCGFCTPGMVMSIYTLLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCKTSGCCQSKEN-GVCCLDQGINGLPEFEEGSKTSPKLFAEEEFLPLDPTQELIFPPELMIMAEKQSQRTRVFGSERMMWFSPVTLKELLEFKFKYPQAPVIMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHAYNG-LTLGAGLSLAQVKDILADVVQKLPEEKTQMYHALLKHLGTLAGSQIRNMASLGGHIISRHPDSDLNPILAVGNCTLNLLS---KEGK-RQIPLNEQFLSKCPNADLKPQEILVSVNIPYSRKWEFVSAFRQAQRQENALAIVNSGMRVFFGEGDGIIRELCISYGGVGPATICAKNSCQKLIGRHWNEQMLDIACRLILNEVSLLGSAPGGKVEFKRTLIISFLFKFYLEVSQILK--------KMDPVHYPSLADKYESALEDLHSKHHCSTLKYQNIGPKQHPEDPIGHPIMHLSGVKHATGEAIYCDDMPLVDQELFLTFVTSSRAHAKIVSIDLSEALSMPGVVDIMTAEHLSDVN-SFCFFTEAEKFLATDKVFCVGQLVCAVLADSEVQAKRAAKRVKIVYQDLEPLILTIEESIQHNSSFKPERKLE-YGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKYIQDIVASTLKLPANKVMCHVRRVGGAFGGKVLKTGIIAAVTAFAANKHGRAVRCVLERGEDMLITGGRHPYLGKYKAGFMNDGRILALDMEHYSNAGASLDESLFVIEMGLLKMDNAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAALITESCITEVAAKCGLSPEKVRIINMYKEIDQTPYKQEINAKNLIQCWRECMAMSSYSLRKVAVEKFNAENYWKKKGLAMVPLKFPVGLGSRAAGQAAALVHIYLDGSVLVTHGGIEMGQGVHTKMIQVVSRELRMPMSNVHLRGTSTETVPNANISGGSVVADLNGLAVKDACQTLLKRLEPIISKNPKGTWKDWAQTAFDESINLSAVGYFRGYESDMNWEKGE-GQPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGCSINPAIDIGQIEGAFIQGMGLYTIEELNYSPQGILHTRGPDQYKIPAICDMPTELHIALLPPSQNSNTLYSSKGLGESGVFLGCSVFFAIHDAVSAARQ---ERGLHGPLTLNSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNVPI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22985-1", "uniprot_id": "XDH_RAT", "id": "P22985-1", "name": "Xanthine dehydrogenase/oxidase", "aln": "-----MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQ-KLHPVQERIARSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCMNQTK--DQTVSL----SPSLFNPEDFKPLDPTQEPIFPPELLRLKDTP-QKKLRFEGERVTWIQASTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEG-ISFGASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVFMASGAKLTLVS----RGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLG-------RADLEDMCGKLDPTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSN--ATGLFNDETVFAKDEVTCVGHIIGAVVADTPEHAQRAARGVKITYEDL-PAIITIQDAINNNSFYGSEIKIE-KGDLKKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAASASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLGYSFETNS-GNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHGD-NAKQLFQLDSPATPEKIRNACVDQFTTLCVTGVPENCKSWSVRI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00519-1", "uniprot_id": "XDH_MOUSE", "id": "Q00519-1", "name": "Xanthine dehydrogenase/oxidase", "aln": "--MTRTTVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCMSQTK--DQTIAP----SSSLFNPEDFKPLDPTQEPIFPPELLRLKDTP-RKTLRFEGERVTWIQVSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEG-ISFGAACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLAS----RGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLG-------RADLEGMCGKLDPTFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSN--ITGIFNDETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDL-PAIITIQDAIKNNSFYGPEVKIE-KGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGYSFETNS-GNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATGTPENCKSWSVRI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47989-1", "uniprot_id": "XDH_HUMAN", "id": "P47989-1", "name": "Xanthine dehydrogenase/oxidase", "aln": "-----MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKK--DHSVSL----SPSLFKPEEFTPLDPTQEPIFPPELLRLKDTP-RKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDG-ISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVS----RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLG-------QENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSN--ITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFYGPELKIE-KGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNS-GNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10351-1", "uniprot_id": "XDH_DROME", "id": "P10351-1", "name": "Xanthine dehydrogenase", "aln": "-----MSNSVLVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAVNACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNAEQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMG----EKCCKVSGKGCGTDAET----DDKLFERSEFQPLDPSQEPIFPPELQLSDAFD-SQSLIFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVGNTEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDG-IYFGAAVSLMEIDALLRQRIEQLPESETRLFQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMGTGFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSNIVAEISMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVSLFFKAYLAISLKLS-------KSGIT-SSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAALKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDLTEHENEVGPVFHDEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKSYFPDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPR-DSDELELFCSTQHPSEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDMLITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPNVRVGGWVCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQLEHFPIERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINIYGDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDACEKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPETNPNARTYSYYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQGMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAARE---DQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPWNIVP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:***:** * . ** ** : *. : * *** .*. *.*******:*: : . * .. *** *:* :: *:*****:*. : ::**:***:*: *.:*****:**:***:*:**** :*: :: :: ************::. ::* ** .*: .:* *:**:** ****** * ..* * .:: *: * .:* * :: * * :* :* .* :: * : :* : * : :** .* :. * * . *. . . * :** *::.:* :**: : **:**:: . : : * : : :. *: : ..:: .: . : ::. .:: * ::: :. *.:.: * * : :: : :*.:. : * .: :.: *. ::. : *: : * ** :: :* :*::* ** : * : : .: : * * :*:* * :. :*:*** : **:. *: : .* *::.:*:* .:* **. *. .. .: : . * .:* * *::: :: *:. ::.*:. :*: * :: * :.*:::::: :* :: *::. .: .*: .* : ******:**: .:*: : *: :. .:* . *. :: :. :: : :* **.**** : .. *..* : *:.:* *:* :*****. *** : :** ** . * : * :: : * * : * * : * ::: :* *:: *.* * * *****:**:**** **. * : ** .: *:*: . * .:* :. : .* *: . : :: .** : *:*:*:.::* *: :.. *..:*:::: ***.*::*** *:***::***:* .:* * :* . :: .* ***: :..* :*:** .: **: : .** * * * *. * *: . :.***.*: :. . : *: *.. : **::**** *: : *:*.:* *:***:*:**:****:** *::* *:: ***:* *::*.* **:. . .:* :: :::: ::*:**.:**. *:..* :*** *: :** . : :* *. :* ** *:** : . . .: ", "identical_positions": 356, "similar_positions": 401, "identity": "26.12%" }, { "cls_id": "homologset.agr.FB:FBgn0003312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35084-1", "uniprot_id": "CP27B_MOUSE", "id": "O35084-1", "name": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "aln": "---MTQAVKLASR------------VFHRIHLPLQLDASLGSRGSESVLR------------------SLSDIPGPS-----TLSFLAELFCKGGLSRLHELQVHGAARYGPIWSGSFG-TLRTVYVADPTLVEQLLRQESHCPERCSFSSWAEHRRRHQRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDNVVRDLVRRLRR---------QRGRGSGLPGLVLDVAGEFYKFGLESIGAVLLGSRLGCLEAEVPPDTETFIHAVG---SVFVSTLLTMAMPNWLHHLIPGPWARLCRDWDQMFAFAQRHVELREGEAAMRNQGKPEEDMPSGHHLTHFLFREKVSVQSIVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTALHSEITAGTR-GSCAHPHGTALSQLPLLKAVIKEVLRLYPVVPGNSR-VPDRDIRVGNYVIPQDTLVSLCHYATSRDPTQFPDPNSFNPARWLGEGPTP-----HPFASLPFGFGKRSCIGRRLAELELQMALSQILTHFEVLPEPGALPIKPMTRTVLVPERSINLQFVDR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35132-1", "uniprot_id": "CP27B_RAT", "id": "O35132-1", "name": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "aln": "---MTQAVKLASR------------VFHRVQLPSQL-------GSDSVLR------------------SLSDIPGPS-----TPSFLAELFCKGGLSRLHELQVHGAARYGPIWSGSFG-TLRTVYVADPALVEQLLRQESHCPERCSFSSWSEHRRRHQRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDSVVSDLVRRLRR---------QRGRGSGLPDLVLDVAGEFYKFGLEGIGAVLLGSRLGCLEAEVPPDTETFIEAVG---SVFVSTLLTMAMPSWLHRLIPGPWARLCRDWDQMFAFAQKHVEQREGEAAVRNQGKPEEDLPTGHHLTHFLFREKVSVQSIVGNVTELLLAGVDTVSNTLSWALYELSRHPEVQSALHSEITGAVNPGSYAHLQATALSQLPLLKAVIKEVLRLYPVVPGNSR-VPDRDICVGNYVIPQDTLVSLCHYATSRDPAQFREPNSFNPARWLGEGPAP-----HPFASLPFGFGKRSCIGRRLAELELQMALAQILTHFEVLPEPGALPVKPMTRTVLVPERSIHLQFVDR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8WGA0-1", "uniprot_id": "C27C1_DANRE", "id": "A8WGA0-1", "name": "Cytochrome P450 27C1", "aln": "MALQSTILHMARKNLLQESCRQLLIQTHGLHKSVASGSLEIAAHSQADLKEESAVSPAEEVQKAARVKSLKEMPGPS-----TVANLLEFFYRDGFSRIHEIQMEHAKKYGKIFKSRFG-PQFVVSIADRDMVAQVLRSESATPQRGNMESWKEYRDLRGRSTGLISAEGDEWLKMRSVLRQLIMRPRDVAVFSSDVNDVVADLVKRVKT---------LRSQQDDS-QTVLNINDLFFKYAMEGVATILYETRLGCLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQIHVDKR--LSEIKKQMEKSEEIKGG-LLTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTYLLARHPTIQQQIFEEVDRVLG---GRVPTGEDVPYLPLIRGLVKETLRLFPVLPGNGR-VTHDDLIVGGYLIPKGTQLALCHYSTSMDEENFPRPEEFRPDRWIRKDASDR---VDNFGSIPFGYGIRSCIGRRIAELEMHLALTQLLQNFHIEVSPQTTEVHAKTHGLLCPGASINLRFTDRK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DBG1-1", "uniprot_id": "CP27A_MOUSE", "id": "Q9DBG1-1", "name": "Sterol 26-hydroxylase, mitochondrial", "aln": "---MAAWSRTRLR--------WTLLDPRVVGRGLCPQGARAKATIPAALQAQESTEGPGTGQDRPRLRSPAELPGTG-----TLQFLFQLFLQGYVLHLPDLQVLNKTKYGPMWTTSFG-TYTNVNLASAPLLEQVMRQEGKYPIRDHMDQWKDHRDHKGLTYGIFIAQGEQWYHLRQALKQRLLKPDEAALYTDALNEVISDFITRLDQ---------VRAE-SESGDQVPDMAHLLYHLALEAITYILFEKRIGCLKPSIPEDTAAFIRSVA---IMFQNSVYITFLPKWTRPLLP-FWKRYLNGWDNIFSFGKKLIDEKVQELKAQLQETGPDGVRVSGYLHFLLTNELLSTQETIGTFPELLLAGVDTTSNTLTWALYHLSKSPEIQEALHKEVTGVVP--FGKVPQHKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVFPEPNSFQPHRWLRKKEADNPGILHPFGSVPFGYGVRSCLGRRIAELEMQLMLSRLVQKYEIALAPGMGEVKTVSRIVLVPSKKVRLHFLQRQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17178-1", "uniprot_id": "CP27A_RAT", "id": "P17178-1", "name": "Sterol 26-hydroxylase, mitochondrial", "aln": "---MAVLSRMRLR--------WALLDTRVMGHGLCPQGARAKAAIPAALRDHESTEGPGTGQDRPRLRSLAELPGPG-----TLRFLFQLFLRGYVLHLHELQALNKAKYGPMWTTTFG-TRTNVNLASAPLLEQVMRQEGKYPIRDSMEQWKEHRDHKGLSYGIFITQGQQWYHLRHSLNQRMLKPAEAALYTDALNEVISDFIARLDQ---------VRTE-SASGDQVPDVAHLLYHLALEAICYILFEKRVGCLEPSIPEDTATFIRSVG---LMFKNSVYVTFLPKWSRPLLP-FWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGPDGVQVSGYLHFLLTKELLSPQETVGTFPELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVP--FGKVPQNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQKYEVVLSPGMGEVKSVSRIVLVPSKKVSLRFLQRQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64441-1", "uniprot_id": "CP24A_MOUSE", "id": "Q64441-1", "name": "1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial", "aln": "---MSCPIDKRRP------------LIAFLRRLRDLGQPPRSVTSKAHVKRAPKEVPLCPLMTDGETRNVTSLPGPTNW--PLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLG-SFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDE---------LRDE----RGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALTFIAAIKTMMSTFG--KMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQ---------PGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLP--DNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTR-TLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWLEKEKKIN-----PFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATD-SEPVEMLHLGILVPSRELPIAFCPR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09128-1", "uniprot_id": "CP24A_RAT", "id": "Q09128-1", "name": "1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial", "aln": "---MSCPIDKRRT------------LIAFLRRLRDLGQPPRSVTSKASASRAPKEVPLCPLMTDGETRNVTSLPGPTNW--PLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLG-SFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFLERMDE---------LCDE----RGRIPDLYSELNKWSFESICLVLYEKRFGLLQKETEEEALTFITAIKTMMSTFG--KMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDNRLQRYSQQ---------PGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQAQRRLLQEVQSVLP--DNQTPRAEDLRNMPYLKACLKESMRLTPSVPFTTR-TLDKPTVLGEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKKIN-----PFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDIVATD-NEPVEMLHLGILVPSRELPIAFRPR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VGH1-1", "uniprot_id": "CP315_DROME", "id": "Q9VGH1-1", "name": "Cytochrome P450 315a1, mitochondrial", "aln": "---MTEKRERPGP-------------LRWLRHLLDQLLVRILSLSLFRSRCDPPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLN-GNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGT--SVLTCPKIQSSLDYFTQIVHK-VFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRR-------PHDEALYHRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKERATNDS---------------RLMHGLIKESLRLYPVAPFIGR-YLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVH---KSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLN-EMPVDSVLRMVTVPDRTLRLALRPRTE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* . * ::: . : . :** :: :* . * :.. :: : : *. * : . * :. : *:: :* :* : * : ::. ::. :: : : : : : .:* : :: . . * : :: : : : * * :: :. : * : . . :: :*. :*.: : * : *:: * * : * ::. :** :** * * * :. . : :.* . * . . * .. . * ** .. :**. * * *:***:* ::: * ::.: :. : * : : : * ", "identical_positions": 50, "similar_positions": 116, "identity": "8.82%" }, { "cls_id": "homologset.agr.FB:FBgn0003317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04771-1", "uniprot_id": "ACVR1_HUMAN", "id": "Q04771-1", "name": "Activin receptor type-1", "aln": "---MVDGVMILPVLIMI------ALPSPSMEDEKPKVNPKLYMCVCEGLS--------------------------------CGNEDHCEG-----------QQCFSSLSINDG-FHVYQKGCFQVYEQGKMTCKTPPSPG-----------QAVECCQGDWCNRN--ITAQ--LPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQ---ERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSL----DKLKTDC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37172-1", "uniprot_id": "ACVR1_MOUSE", "id": "P37172-1", "name": "Activin receptor type-1", "aln": "---MVDGVMILPVLMMM------AFPSPSVEDEKPKVNQKLYMCVCEGLS--------------------------------CGNEDHCEG-----------QQCFSSLSINDG-FHVYQKGCFQVYEQGKMTCKTPPSPG-----------QAVECCQGDWCNRN--ITAQ--LPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACILGVALRKFKRRNQ---ERLNPRDVEYGTIEGLITTNVGDSTLAELLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSL----DKLKTDC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80201-1", "uniprot_id": "ACVR1_RAT", "id": "P80201-1", "name": "Activin receptor type-1", "aln": "---MVDGAMILSVLMMM------ALPSPSMEDEEPKVNPKLYMCVCEGLS--------------------------------CGNEDHCEG-----------QQCFSSLSVNDG-FRVYQKGCFQVYEQGKMTCKTPPSPG-----------QAVECCQGDWCNRN--VTAR--LPTKGKSFPGSQNFHLEVGLIILSVVFAVCLFACILGVALRKFKRRNQ---ERLNPRDVEYGTIEGLITTNVGDSTLAELLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSL----DKLKTDC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QFK8-1", "uniprot_id": "A0A8M9QFK8_DANRE", "id": "A0A8M9QFK8-1", "name": "receptor protein serine/threonine kinase", "aln": "---MGHCSTQIIILFLL------QFLQTSAKDVS-------IDCMCVGSD--------------------------------C-NEQQCTG-----------DQCYTSVIISND-VTTFKRGCLIGPASKRMTCSATASAS-----------HVVECCSQHMCNAN--VSKETLLRLLLTSPEEGKTVHYRVEMLVLFVLGPFVVLGLLSFLALLVCRRLHHGRLERLHEFDTEQGAIDGLIASNVGDSTLADLMDHSCTSGSGSGLPFLVQRTVARQISLVECVGKGRYGEVWRGQWQGENVAVKIFSSRDEKSWFRETEIYNTVLLRHENILGFMASDMTSRNSSTQLWLITHYHENGSLYDYLQRVAVEMADGLHMAASIASGLVHLHTEIFGTEGKPAIAHRDLKSKNILVKKDLQCCIADLGLAVTHTQSDNQLDVGNNPKVGTKRYMAPEVLDETIQTDCFDAYKRVDIWAFGLVLWEIARRTISNGIVEEYKPPFYDLVPNDPSFDDMRKVVCVEQQRPFIPNRWFSDPTLSALVKLMKECWYQNPSARLTALRIKKTLDKIHSSL----EKGKTDC-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P80203-1", "uniprot_id": "ACVL1_RAT", "id": "P80203-1", "name": "Activin receptor type-1-like", "aln": "---MTLGIFRRVFLMLS--VALGLTKGDLVKPSRGQ----LVNCTCENP---------------------------------HCKRPICQG-----------AWCTVVLVREQGRHPQVYRGCGSLNQEL---CLGRPTEF-----------VNHHCCYRSFCNHN--VSLM----LEATQTPSEEPEVDAHLPLILGPVLALLVLVALGTLGLWRVRRRQE--KQRGLHSDLGESSLI-LKASEQGDSMLGDFLVSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSQNP----EKPKVIH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61288-1", "uniprot_id": "ACVL1_MOUSE", "id": "Q61288-1", "name": "Activin receptor type-1-like", "aln": "---MTLGSFRRGLLMLS--VAFGLTRGDLAKPSK------LVNCTCESP---------------------------------HCKRPFCQG-----------SWCTVVLVREQGRHPQVYRGCGSLNQEL---CLGRPTEF-----------LNHHCCYRSFCNHN--VSLM----LEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQE--KQRDLHSDLGESSLI-LKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNP----EKPKVIH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37023-1", "uniprot_id": "ACVL1_HUMAN", "id": "P37023-1", "name": "Activin receptor type-1-like", "aln": "---MTLGSPRKGLLMLL--MAL-VTQGDPVKPSRGP----LVTCTCESP---------------------------------HCKGPTCRG-----------AWCTVVLVREEGRHPQEHRGCGNLHREL---CRGRPTEF-----------VNHYCCDSHLCNHN--VSLV----LEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRRRQE--KQRGLHSELGESSLI-LKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNSP----EKPKVIQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P4Z5-1", "uniprot_id": "A0A8M9P4Z5_DANRE", "id": "A0A8M9P4Z5-1", "name": "receptor protein serine/threonine kinase", "aln": "MRDMKASVMLAVLFVLVYSGSYATTADHLMETSTLKNDESSLQCSCENTN--------------------------------LCENNSCWG-----------RICFYTSVHER-----VVRGC-FQTAEQ---CYVPAIPG-----------VYTKCCYTHHCNAN--LTMP----EKPVCLFSVEKPIR--VILLVGVPLLVLLVIAMAACGLVLWLR-----TRRQYCHPVEHDTSM-LKVPSGGDPTYGDIFDEFCTSGSGTGLPYLVQRTMARQISLVECVGKGRYGEVWRGTWMGESVAVKIFSSRDEQSWFRETEIYNTVQLRHENILGFIASDMTSKNSSTQLWLVTHFHELGSLYDFLQYSTLDPEGCLRMCLSIASGLVHLHTEILSTQGKPAIAHRDLKSRNILVKRNGQCCIADLGLAVIHSQSTDYLDVGTNPRVGTKRYMAPEVLDETIRVDVFESYKQTDIWALGLVLWEITRRTIVNGIVEEYRPPFFDMVPSDPSFEEMKKVVCVDQHRPSLHNRLHSHPILSAIAKIMKECWFQSPSARLTALRVRKSLSKLDQDHDYDIDKLKLDL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7J3-1", "uniprot_id": "A0A0B4K7J3_DROME", "id": "A0A0B4K7J3-1", "name": "receptor protein serine/threonine kinase", "aln": "---MESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRRHIKSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASAD----EKIRLDFDEVCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : . . . * . * . :** . * . ** ** . :: . . : : * . * ... .*. : : *:***:*** *****:*:*::*:**:*:*:******* * **.:***** ****:** ****:*.*: ***:*****:.*****::*.*****:**:: ***:*.*: ::. : : * * **.*** **:..:**.*:****:**:*:**. : .* ***:**** *:: . **:*.**:************** * : *:: : .**:*:******: ** : **.*:*: **:*:** ****::*:****::: * : ** :.. ::.: ::*:***. .*..**.***::*:: *: :* : ", "identical_positions": 181, "similar_positions": 122, "identity": "30.73%" }, { "cls_id": "homologset.agr.FB:FBgn0003319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LTS6-1", "uniprot_id": "A0ABK0LTS6_RAT", "id": "A0ABK0LTS6-1", "name": "Enteropeptidase", "aln": "-----KSIRNVAAGHRSISSFEVMVSALFMVLMVLSVGLIVVSWLAVKESETDAAALGKSHEVRGRFKITSGVTYNPNLQDKFSVDFKVLAFDLQQMIDEIFESSNLKNEYKKSRVFQFENGSVIVLFDLFFAQWVSDENVKEELIQGIEANISSQLVTLHIDLNSIDIAASLSNFSTPFPLTTSDKIASS-LMTTSGSLDNFSTPTVTTTSGSLDNFSTPIGTTTSGNVSVECQPGSRPCANAWDCVATDLFCDGEVNCPDGADEDTGLCATACDGRFLLTGDSGVFQANRYPRPDESGVVCRWIIRVNQGLSVRMSFGKFISHYTDVLDIYEGIGPSKILRGSFWETDPGTIRIFSNQVTVTFLIKSDEYDYIG---FNATYSTFNSSEINNYEKINCTFDDGFCFWTQDLDDDNEWERNQMARFPCYTGPFSDHTFGNESGFYISTPAEQAWKSERVGLSSLSLGFTSEPVCLHFWYYMCCENVYNLNIHVSSTETTDKIVFQRQGNYGRNWNYGQVTLNETVEFKVVFNAFRNRGCSTIALDDISLTNGICSESPYP-EPTLVPTPPPEHPTDCGGPFELWEPNTTFSSPNFPDNYPNQAFCIWNLNAQSGKNIQLHFQEFDLENINDVVEVRDGVKFDSLLLAVYTGRGPVKDLFSTTNRMTVIFDTDMKNGGKGFKANFTSGYYLGIPQPCQDDEFQCKDGNCIPMGNLCDSYQHCSDGSDEAHCVRFLNGTQSNNGLVQFNIHNIWHIACAEPWTTQISNEVCHLLGLGS-----ANSSMPILSTGGGPFVRLNEAPNGSLILTPSLQCSQDSLILLQCNHKSCGEKM----------------VTQKVGPKIVGGSDTQAGAWPWVVALYYRDRS--GDRLLCGASLVSSDWLVSAAHCVYRRN--LDPTR----WTAVLGLHMQ--SNLTSPQVVRRVVDRIVINPHYDKRRKVNDIAMMHLEFKVNYTDYIQPICLPEENQTFTPGRMCSIAGWGYNKINAGSTVD--VLKEADVPLVSNEKCQQQLP--------EYDITESMLCAGYEEGGTDSCQGDSGGPLMCQENN-RWFLVGVTSFGVQCALPNHPGVYARVSQFIEWIHSFLH---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97435-1", "uniprot_id": "ENTK_MOUSE", "id": "P97435-1", "name": "Enteropeptidase", "aln": "----MKSSRDEAVGHHSISSFEVMLSALFIMLMVFSIGLIAVSWLAVKESEGD-AALGKSHEVRGTFKITSGVTYNPNLQDKHSVDFKVLAFDLQQMIDEIFESSSLKNEYEKSKVFQFEKGSVIVLFDLFFAQWVSDKNVKEELIQGIEANISSQLVTLHIDLNSIDITASLSDFTTAVPVTTSDKLTTSSPMTTSASLGNLSTTVAATTSAPLCNLSTATFATTSGHVSIECQPGSRPCAHAWNCVATDLFCDGEVNCPDGSDEDTGLCATACDGRFLLTGDSGVFQADRYPRPDESGVVCRWIIRVNQGLSIRMNFGSFIPHYTDVLDIYEGIGPSKILRGSFWETDPGTIRIFSNLVTVTFLIKSDEYDYIG---FNATYSTFNNSELNNYEKIDCTFDDGFCFWTQDLDDDNEWERIQVTTFPCYTGPRFDHTYGNGSGFYISTPTEQGWRSERVGLSSLSLDLTSEPVCLHFWYYMCCENVYNLNIHISSAETTDKIVFQRKGNYGRNWNYGQVTLNETGEFKVVFNAFRNRGCSTIALDDISLTNGICSQSPYP-EPTLVPTPPPELPTDCGGPFELWEPNSTFSSPNFPDKYPNQASCIWNLNAQRGKNIQLHFQEFDLENINDVVEVRDGGEFDSLLLAVYTGPGPVKDLFSTTNRMTVIFTTNMETRRKGFKANFTSGYYLGIPEPCQDDEFQCKDGNCIPLGNLCDSYPHCRDGSDEASCVRFLNGTRSNNGLVQFNIHSIWHIACAENWTTQISNEVCHLLGLGS-----ANSSMPISSTGGGPFVRVNQAPNGSLILTPSLQCSQDSLILLQCNHKSCGEKK----------------VTQKVSPKIVGGSDAQAGAWPWVVALYHRDRS--TDRLLCGASLVSSDWLVSAAHCVYRRN--LDPTR----WTAVLGLHMQ--SNLTSPQVVRRVVDQIVINPHYDRRRKVNDIAMMHLEFKVNYTDYIQPICLPEENQIFIPGRTCSIAGWGYDKINAGSTVD--VLKEADVPLISNEKCQQQLP--------EYNITESMICAGYEEGGIDSCQGDSGGPLMCQENN-RWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWIHSFLH---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98073-1", "uniprot_id": "ENTK_HUMAN", "id": "P98073-1", "name": "Enteropeptidase", "aln": "----MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRG-AALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDI---------------------------------------------LDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVG---FNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYP-EPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGS-----GNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKL----------------AAQDITPKIVGGSNAKEGAWPWVVGLYYGG------RLLCGASLVSSDWLVSAAHCVYGRN--LEPSK----WTAILGLHMK--SNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWG-TVVYQGTTAN--ILQEADVPLLSNERCQQQMP--------EYNITENMICAGYEEGGIDSCQGDSGGPLMCQENN-RWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O15393-1", "uniprot_id": "TMPS2_HUMAN", "id": "O15393-1", "name": "Transmembrane protease serine 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALNSGSPP-------AIGPYYENHGYQPENPYPAQPTVVPT---------------------------------------VYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKT----------KKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKS--WHPVCQDDWNENYGRAACRDMGYKNN---FYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVN----------------LNSSRQSRIVGGESALPGAWPWQVSLHVQN------VHVCGGSIITPEWIVTAAHCVEKPL--NNPWH----WTAFAGILRQ--SFMFYGAGYQ--VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEE-KGKTSE--VLNAAKVLLIETQRCNSRYVY-------DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNN-IWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYE2-1", "uniprot_id": "TMPSD_HUMAN", "id": "Q9BYE2-1", "name": "Transmembrane protease serine 13", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQ--WLPICSSNWNDSYSEKTCQQLGFES----AHRTTEVAHRDFANSFSILRYNS----TIQESLHRSECPSQRYISLQCSHCGLR----------------AMTG---RIVGGALASDSKWPWQVSLHFGT------THICGGTLIDAQWVLTAAHCFFVTR--EKVLEG---WKVYAGTS----NLHQLPEAAS--IAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSP--FLREVQVNLIDFKKCNDYLVY-------DSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNN-RWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEVRSLQQDTAPSRLGTSSGGDPGGAPRL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y5Y6-1", "uniprot_id": "ST14_HUMAN", "id": "Q9Y5Y6-1", "name": "Suppressor of tumorigenicity 14 protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSDRARKGGGGPKDFGAGLKYNSRHEKVNGLEEGVEFLPVNNVKKVEKHGPGRWVVLAAVLIGLLLVLLGIG----------------FLVWHLQYRDVRVQKVFNGYMRITNENFVDAYENSNSTEFVSLASKVKDALKLLYSGVPFLGPYHKESAVTAFSEGSVIAYYWSEFSIPQHLVEEAERVMAEERVVMLPPRARSLKSFVVTSVVAFPTDS-KTVQRTQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHAR-----------CQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCP-KDYVEINGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLS---YDSSDPCPG-QFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALG-----QGHICGASLISPNWLVSAAHCYIDDR--GFRYSDPTQWTAFLGLHDQ--SQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWG-HTQYGGTGAL--ILQKGEIRVINQTTCENLLP---------QQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKENTGV--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6M0-1", "uniprot_id": "TEST_HUMAN", "id": "Q9Y6M0-1", "name": "Testisin", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGARGALLLALLLA-RAG-------------LRKPESQEAAPLSGPCGRR----------------------VITSRIVGGEDAELGRWPWQGSLRLWD------SHVCGVSLLSHRWALTAAHCFETYSDLSDPSG----WMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED-EALPSPHTLQEVQVAIINNSMCNHLFLKY----SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNG-LWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPLLGPV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHJ7-1", "uniprot_id": "TEST_MOUSE", "id": "Q9JHJ7-1", "name": "Testisin", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGARGKTLVPLLVV-VATAAMALQSTYLQVDPEKPELQEPDLLSGPCGHR----------------------TIPSRIVGGDDAELGRWPWQGSLRVWG------NHLCGATLLNRRWVLTAAHCFQKD---NDPFD----WTVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKYSEQYPNDIALLKLSSPVTYNNFIQPICLLNSTYKFENRTDCWVTGWGAIGED-ESLPSPNTLQEVQVAIINNSMCNHMYKKP----DFRTNIWGDMVCAGTPEGGKDACFGDSGGPLACDQDT-VWYQVGVVSWGIGCGRPNRPGVYTNISHHYNWIQSTMIRNGLLRPDPVPLLLFLTLAWASSLLRPA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABF2-1", "uniprot_id": "D4ABF2_RAT", "id": "D4ABF2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVQGPMLLLLLLVVCVMLGEPGSREENQAAG--LKNTDIKLLSMPCGRRN---------------------DIRSRIVGGIESVRGRWPWQASLRLRK------FHRCGGSLLSHRWVLTAAHCFRKF---LDPKK----WTVQLGQLTSKPSFWNREAFSGRYRVKDIIINSEDK-LKYHDLALLRLASSVTYNKFIQPVCVLPSASMSQHQPRCWVTGWGALQEDLKPLPPPYHLREVQVTVLNLSRCQELFSFA----SRYHLITRDVFCAGAEDGSADTCSGDSGGPLVCNMDG-LWYQIGIVSRGVGCGRPKLPGIYTNVSHHYDWIKTMMILNGAVRHDLALPLLFFTPLQAPWLLRPT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920S2-1", "uniprot_id": "PRS41_MOUSE", "id": "Q920S2-1", "name": "Serine protease 41", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGIQGPVLLLLLL--CVMLGKPGSREESQAAD--LKSTDIKLLSMPCGRRN---------------------DTRSRIVGGIESMQGRWPWQASLRLKK------SHRCGGSLLSRRWVLTAAHCFRKY---LDPEK----WTVQLGQLTSKPSYWNRKAYSGRYRVKDIIVNSEDK-LKSHDLALLRLASSVTYNKDIQPVCVQPSTFTSQHQPRCWVTGWGVLQEDLKPLPPPYHLREVQVSILNNSRCQELFEIF----SLHHLITKDVFCAGAEDGSADTCSGDSGGPLVCNMDG-LWYQIGIVSWGIGCGRPNLPGIYTNVSHYYNWIETMMILNGAVRRDLALPLLSITLLQAPWLLRPT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTY9-1", "uniprot_id": "PRS41_HUMAN", "id": "Q7RTY9-1", "name": "Serine protease 41", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGARGALLLALLLA-RAGLGKPGELGALQAGPGAARRPGGGGREEACGHR----------------------EIHALVAGGVESARGRWPWQASLRLRR------RHRCGGSLLSRRWVLSAAHCFQKH---YYPSE----WTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQP----SSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDG-LWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHS-TPRPNPSQLLLLLALLWAP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QYZ9-1", "uniprot_id": "PRS30_MOUSE", "id": "Q9QYZ9-1", "name": "Serine protease 30", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESRAR-CIFLLLL-------QILTRARG---------DILPSVCGHSR--------------------DAGKIVGGQDALEGQWPWQVSLWIT-----EDGHICGGSLIHEVWVLTAAHCFRRSL---NPSF----YHVKVGGLTL--SLLEPHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTPLRPSQFT-PVCLPAAQTPLTPGTVCWVTGWGATQER-DMASV---LQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAGYVEGQKDSCQGDSGGPLVCSINS-SWTQVGITSWGIGCARPYRPGVYTRVPTYVDWIQRILAENHSDAYGYHSSASAAYQMLLPVLLAVALPGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14272-1", "uniprot_id": "KLKB1_RAT", "id": "P14272-1", "name": "Plasma kallikrein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILFKQVGYFVSLFATVSCGCLSQLYANTFFRGGDLAAIYTPDAQHCQKMCTFHPRCLLFSFLAVSPTKETDKRFGCFMKESITGTLPRIHRTGAISGHSLKQCGHQLSACHQDIYEGLDMRGSNFNISKTDSIEECQKLCTNNIHCQFFTYATKAFHRPEYRKSCLLKRSSSGTPTSIKPVDNLVSGFSLKSCALSEIGCPMDIFQHFAFADLNVSQVVTPDAFVCRTVCTFHPNCLFFTFYTNEWETESQRNVCFLKTSKSGRPSPPIIQENAVSGYSLFTCRKARPEPCHFKIYSGVAFEGEELNATFVQGADACQETCTKT-IRCQFFTYSLLPQDCKAEGCKCSLRLSTDGSPTRITYEAQGSSGYSLRLCKVVESSDCTTK--------------------INARIVGGTNSSLGEWPWQVSLQVKL-V--SQNHMCGGSIIGRQWILTAAHCFDGIP---YPDV----WRIYGGILNL--SEITNKTPFSSIKELIIHQKYKMSEGS-YDIALIKLQTPLNYTEFQKPICLPSKADTNTIYTNCWVTGWGYTKERGETQNI---LQKATIPLVPNEECQKKYR--------DYVITKQMICAGYKEGGIDACKGDSGGPLVCKHSG-RWQLVGITSWGEGCARKEQPGVYTKVAEYIDWILEKIQS--SKERALETSPA-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NF86-1", "uniprot_id": "PRS33_HUMAN", "id": "Q8NF86-1", "name": "Serine protease 33", "aln": "--------------------------------------------------------------MRGV------------------SCLQVLLLLVLG------------------------------------AAGTQGR-----------------KSAACGQP----------------------------------------------------------------RMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLRPG------------------------------------------------------VPLPEWRP----------------------------------------------------------LQGVRVPLLDSRTCDGLY------------------------------------------------------------------------------------------------HVGADVP-------------------------------------------------------------------------------------------------QAERIVLPGS-----------------------------------------------------------------------------------------------------------------------------------------------------LCAGYPQGHKDACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7Z410-1", "uniprot_id": "TMPS9_HUMAN", "id": "Q7Z410-1", "name": "Transmembrane protease serine 9", "aln": "MEPTVADVHLVPRTTKEVPALDAACCRAASIGVVATSLVVLTLGVLLAFLSTQGFHVDHTAELRGIRWTSSLRRETSDYHRTLTPTLEALLHFLLRPLQTLSLGLEEELLQRGIRARLREHGISLAAYGTIVSAELTGRHKGPLAERDFKSGRCPGNSFSCGNSQ-------------------------------CVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCA--GYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRR-----REHRCGAVLVAERWLLSAAHCFDVYG---DPKQ----WAAFLGTPFL-----SGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQ---LQKAAVRLLSEQTCRRFYPVQ---------ISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9GZN4-1", "uniprot_id": "BSSP4_HUMAN", "id": "Q9GZN4-1", "name": "Brain-specific serine protease 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQ--------------------QLNRVVGGEDSTDSEWPWIVSIQKNG------THHCAGSLLTSRWVITAAHCFKDNLN--KPYL----FSVLLGAWQLG--NPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHP-QTLQKLKVPIIDSEVCSHLYWRG----AGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDG-AWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05319-1", "uniprot_id": "STUB_DROME", "id": "Q05319-1", "name": "Serine proteinase stubble", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKQPTLIRPRLRHRRSTPAAATKMCPKRHWLVNNRAAGSRGSGGAAARSRRSLDQIVEVLVALIVVNCLATAAAALITPPDSLESLGSLGIPSSSASSSEDDDDMSSGFYRIPHRLEGYPQLQQLQRGQNFKISPKPCSFG--------------------------------------------------------------------------------RVEGTCMFVWECIKSEGKHVGMCVDSFMFGSCCTHNYTDNIVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPHGAGTLVIRPSGPHHQGTLARPHPPPYQSKPTTASDLHGSASHPSSSSSSSSSSNPNSIWHTSTQQQQQQQHQQNQQNHWQMTTEPSFITKPRPTGWTKPGIVNLPMPARPSKPSKPTKKPIVYDRTPPPPPSVPPSTSTSTTSTSLIWPAQTHPPQPHRPTRPQLSPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTTTTRRTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISSSSSSSSGIVTSSQRPTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGVPTLAR-------------------PETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIR--------VGEYDFS-HVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDS-LLIGMNATVTGWGRLSEGGTLPSV---LQEVSVPIVSNDNCKSMFMRAG----RQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... .*.* * *:* **:**** * * * *. **: : *: ", "identical_positions": 18, "similar_positions": 11, "identity": "1.56%" }, { "cls_id": "homologset.agr.FB:FBgn0003321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M355-1", "uniprot_id": "F1M355_RAT", "id": "F1M355-1", "name": "Tip-associated protein", "aln": "---------------------------------------------MESRSET----NPFRRRMRCRRIFRRRFLNSTEYISDTMRTSFYHQQDEELAMSNAPMYTR------RRYTPYGILSHHQRINLHKWDQMNVNMEEGAKPPERKME--------RDKQDDTSENWFKVTIPFGIKYDKKWMLNLIQSQCS-IPFTPVQFHYEKMQATFFVDDPNIAFMLKAISDKIRDETDNKPQSHITPS---------------VILQLTMN------QQCDTSQRILNRQRLSFDQDLTTYPTDLVLSPRRYMTPSLNISEEDVTQAN------------------------------------SEGKMAKEQASDIEEICAVKSSLSTTMPDKSSNINSILELFPKLLSLDGQESCKPALCGPEDQKTISTYKRSFFESESIKTLVLQFLQQYYFIYDNGDREGLLNAYHADACFSLTVPFSTMDLSASSVCEYVKYSRSMKVLKDPYMRKQLLKHKKC-DIIHFLRALPKTQHDLTSFSVDICFQTEKTLCFSVSGLFKEVEGSSQG-------CFHAFTRIFVAT-WDNSDLCIINDKLSVRNVYGFPSAS---NAVDTCSSSRLPSLSQDQQQMMPTFC------------------------------------------------------------SQSGVNVERSQKCLHDDQWNYNKAIQSFALLKVKDTVPEDKTTHTSPRS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4D5-1", "uniprot_id": "NXF3_HUMAN", "id": "Q9H4D5-1", "name": "Nuclear RNA export factor 3", "aln": "-------------------------------------------MSLPSGHTTGHTDQVVQRRARCWDIYQRRFSSRSEPVNPGMHSSSHQQQDGDAAMHGAHMDSP------VRYTPYTISPYNRKGSFRKQDQTHVNMEREQKPPERRME--------GNMPDGTLGSWFKITVPFGIKYNEKWLLNLIQNECS-VPFVPVEFHYENMHASFFVENASIAYALKNVSGKIWDEDNEKISIFVNPAGIPHFVHRELKSEKVEQIKLAMN------QQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAASLDVHEENIPTVM------------------------------------SAGEMDKWKGIEPGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRLPTCKGSFFGSEMLKNLVLQFLQQYYLIYDSGDRQGLLSAYHDEACFSLSIPFNPEDSAPSSFCKFFKDSRNIKILKDPYLRGELLKHTKL-DIVDSLSALPKTQHDLSSFLVDMWYQTEWMLCFSVNGVFKEVEGQSQG-------SVLAFTRTFIATPGSSSSLCIVNDKLFVRDTSHQGTQSALFTLVPTAFSSSVPAFSQEQQKMLPS--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9GZY0-1", "uniprot_id": "NXF2_HUMAN", "id": "Q9GZY0-1", "name": "Nuclear RNA export factor 2", "aln": "-------------------------------MCSTLKKCGTYRTEVAECHDHGSTFQGRKKGGSSFRDNFDKRSCHYEHGGYERPPSHCQENDGSVEMRDVHKD------QQLRHTPYSIRCE-RRMKWHSEDEIRITTWRNRKPPERKMS--------QNTQDGYTRNWFKVTIPYGIKYDKAWLMNSIQSHCS-DRFTPVDFHYVRNRACFFVQDASAASALKDVSYKIYDDENQKICIFVNHSTAPYSVKNKLKPGQMEMLKLTMN------KRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIIERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQYYSIYDSGDRQGLLGAYHDEACFSLAIPFDPKDSAPSSLCKYFEDSRNMKTLKDPYLKGELLRRTKR-DIVDSLSALPKTQHDLSSILVDVWCQTERMLCFSVNGVFKEVEGQSQG-------SVLAFTRTFIATPGSSSSLCIVNDELFVRDASPQETQSAFSIPVSTLSSSSEPSLSQEQQEMVQAFS------------------------------------------------------------AQSGMKLEWSQKCLQDNEWNYTRAGQAFTMLQTEGKIPAEAFKQIS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H1B4-1", "uniprot_id": "NXF5_HUMAN", "id": "Q9H1B4-1", "name": "Nuclear RNA export factor 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MR--------RNTQDENMRKWFKVTIPYGIKYDKAWLMNSIQSNCS-VPFTPVDFHYIRNRACFFVQVASAASALKDVSYKIYDDENQKICIFVSHFTAPYSVKNKLKPGQMEMLKLTMN------KRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKITERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQ------------------------------------SNLCKYFKDSRNIKILKDPYLQRKLLKHTKCPRNVDSLSALPETQHDFTSILVDMWYQT-------VNTCFLPRAG-----------------------PESQRWWCLLS--LKWKDG----------LRVLILPSCGPSSLPLAAIPVCAS--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LCE1-1", "uniprot_id": "A0ABK0LCE1_RAT", "id": "A0ABK0LCE1-1", "name": "", "aln": "--------------------------------------------------------------MSSFQEVSGNKNLYDEFHLDTVLPPQLQDNDGNMQIMDANGDPQMLYEQQLKSSLESLESS-YTFSVKEDCGTTYSACQEKTLSDEEMN--------RSILGEVFERWFKITIPNGKKYNKMWLINLLQSYCS-MGFTPVDFQYIRNGIQFFVQSTKTAVELMNINYQISDEENKKISIYVNSSSEPASVHYKLTAAQMHSLKLSMK------KRYDVSKKALYLGKLRFDQDLMDHGIDMFLNRRSCMTAALQIIQENFPELLSLNVSNNKIYWLDGLSELIEKAPHVKTLNLSRNLLRTAWELEKIRGLNLEQLWLEGNPLCSTFPDHSSYVSAILNYFPELSHLDGRKLFP--TIDINTLEIIKPRKESYKGSECLKNLLVQFMLQYYLIYDYGDRHSLLNAYHANACFSLAITFNSDKADMSSLEDYLKDNRNMKMLTNSFLRMQLLKHKKY-NIVTCLHELPKTQHDLNSYVVDICVQTEKMICFSVNGVFKEVEGKSWG-------SVRAFTRTFILTPDRHFRLCIVNDEMILRNANPAEARKAFSTTRPTVSYTQSCWNTHTDLKLCGMREGIV----------------------------------------------------RTSGNASERMKPSLHSRVRKDPQVNSSDTSSERSPWKLSSSSSTLLFVCFFLSHSPGQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z8R9-1", "uniprot_id": "D3Z8R9_RAT", "id": "D3Z8R9-1", "name": "Tip-associated protein", "aln": "-------------------------------MWSSPDKDPEDRPSMIVLKNTN---SETQKHRYDLPYKRSETHCHSEYKMSHRRGFQGRKRGANYIWHKFDRRNN---HFNYPGTPYAVGLK-RRKERYSYEDRYFLTVWNDRKTEECED--------LYAERRATERWYKVTIPSGRKYEKTWLINSIQKLCT-VPFVPVDFHYDKNRARFFVQDAKIASALKDVNLKICDETSRKISLFVSPSVVPYSVQNKFSSEQMEHLKISIM------KRYDASQKALDLEKFRFDQDLMDKDIDMMLNRRSCMVATLQIIESNIPELLSLNLKNNKLYQLDGLSDMTEKAPQVKILNLSRNKLKSIFELEKVKELKLEELWLEGNPFCNCYLDDSEYISAVRDLFPKLLRLDGRELIVPTGMDIEAP---QLCKKTHNETELIKNLVLRFLKEYYLFYDNGDRLRLLDAYHDQACFSLSVPFNVSDPDLDNLEEYLKYNRDIKKQQDSNMRVQLLKHTKH-DIVTSLSLLPKTQHDLCSFWVDLCFHSEMMLCFSVNGLFKEVEGKCQG-------CIRAFTRIFIAIPCSDSRICIMNDELIVRNASPKEIQKAF-TSSPAPDTSLKPLLSAEQQEMVKSFS------------------------------------------------------------VQSGMKLDWSQKCLEDNEWDYTKAGEAFTALQNEGKIPKEFFK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JX7-1", "uniprot_id": "NXF1_MOUSE", "id": "Q99JX7-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------------------MADEGKSYNEHDD-RVSFPQ-----RRKKGRGPFRWKCGEGNRRSGRGGSGVQSSRFEEDDGDVAMNDPQDG------PRVRYNPYTNRPNRRGDGWHDRDRIHITVRRDRAPAERGG--------AGTSQDGTTKNWFKITIPYGRKYDKTWLLSMIQSKCS-VPFNPIEFHYENTRAHFFVEDATTASALKGVNHKIQDRENRRISIIINASAPPYTVQNELKPEQIEQLKLIMS------KRYDGNQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSSNRLYKLDDMSSIVQKAPNLKTLNLSGNELKTERELDKIKGLKLEELWLDRNPMCDNFGDQSSYISAIRERFPKLLRLDGHELPPPISFDVEAPTMLPPCKGSYFGTENLKSLVLRFLQQYYVIYDSGDRQGLLYAYHDGACCSLSIPYNPQNPVRKNLAEYVKDSRNVKKLKEPTQRFRLLKHTRL-NVVAFLNELPKTQHDVNAFVVDISAQTSTLLCFSVNGVFKEVDGKSRD-------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMSAPTPSSSPVPTLSPEQQEMLQAFS------------------------------------------------------------TQSGMNLEWSQKCLQDNNWDYTRSAQAFTLLKAKGEIPEVAFMK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88984-1", "uniprot_id": "NXF1_RAT", "id": "O88984-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------------------MADEGKSYNEHDD-RVSFPQ-----RRKKGRGPFRWKCGVGNRRSGRGGSGIRSSRFEEDDGDVAMNDPQDG------PRVRFNPYTTRPNRRRDTWHDRDRIHVTVRRDRAPQERGG--------AGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCS-VPFNPIEFHYENTRAHFFVENATTASALKAVNYKIQDRENGRISIIINSSAPPYIVQNELKPEQVEQLKLIMS------KRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIPELLSLNLSNNRLYKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQSTYISTIRERFPKLLRLDGHELPPPIAFDVEAPTMLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSTPSNPQNPVRHNLAKYFNDSRNVKKIKDTTTRFRLLKHTRL-NVVAFLNELPKTHHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRD-------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPSSSPVPTLSQEQQDMLQAFS------------------------------------------------------------TQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBU9-1", "uniprot_id": "NXF1_HUMAN", "id": "Q9UBU9-1", "name": "Nuclear RNA export factor 1", "aln": "--------------------------------MADEGKSYSEHDDERVNFPQ-----RKKKGRGPFRWKYGEGNRRSGRGGSGIRSSRLEEDDGDVAMSDAQDG------PRVRYNPYTTRPNRRGDTWHDRDRIHVTVRRDRAPPERGG--------AGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQSKCS-VPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIMS------KRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAFDVEAPTTLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSIPFIPQNPARSSLAEYFKDSRNVKKLKDPTLRFRLLKHTRL-NVVAFLNELPKTQHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRD-------SLRAFTRTFIAVPASNSGLCIVNDELFVRNASSEEIQRAFAMPAPTPSSSPVPTLSPEQQEMLQAFS------------------------------------------------------------TQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H6Y3-1", "uniprot_id": "A0AC58H6Y3_DANRE", "id": "A0AC58H6Y3-1", "name": "", "aln": "MSRYREWYPNLSVITRVCSSSSDSSGSTVVREVWHADRSFTGQDGHLVGVRQSWGSVKANLHNGPARLLHGSGAR--GRCGSGPRG-RMQNSSMDVSLMNGQFGT-----AKQRFIPYR-RPSWRGEGQVEMIGEGNKQRFRVGDEKKGGKQWFKMTLCFLQLLDASRVPLKQPIPHGKKYDKRWLLTSLQNLCP-IAFTPLHYTTEGDKVHFYLEDTTTASALSKLSRRILDSDGQRVVVLMNSCYFPPFLKSELRLEDLELLKLCLS------KRFDDSQKSLDLTSIRTDPELVSHNVDIILNRKNCMQAVIKIIQESIPELLSLNLSKNKLYKLDGLTELVNKAPNLQSLNLSCNELKSHCELDKVKGFRLVELCLDGNPLCDRFKDQTTYISAVQKCFPRLLRLDGHVLSLPICFEVETSSNIPLCKGSHFVSNEIQGLIQRFLEQYYSIYDSGDRQPLLEAYHESACFSLCLPSIS-NPSRYKL-DYFKNSRNVKNIKDSPTRFRLLKHTRL-TVVACLNELPKTQHDINSINVDVNAYASTLLAFTVSGVFKEVDDQSED-------LFKAFSRVFVTVPAQNSGLCIVNDELFVRNTTMEEIQCAFTTPTQSPSSSPVPILSAYQQEMLSAFS------------------------------------------------------------QMSEMNLQWSQKCLEDNAWDFQQAAQIFAELQAHGMIPEAAFIK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1H9-1", "uniprot_id": "NXF1_DROME", "id": "Q9U1H9-1", "name": "Nuclear RNA export factor 1", "aln": "----------------------------------MPKRGGGSSQRYNNNVGNGGGRYNAPEDFDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPEDLR--------------RWDEDDDMSDMTTAVKDRPTSRRRGSPIPRGKFG---------KLMPNSFGWYQVTLQNAQIYEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDDYEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLVAIDDAFK----EKMKVTMA------KRYNIQTKALDLSRFHADPDLKQVFCPLFR--QNVMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRYKDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYHEKAMLSISMPSASQAGRLNSFWKFNRNLR--RLLNGEENRTRNLKYGRL-ACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVFTVTGLFKELNDETNNPASMELYDVRHFARTYVVVPQNNG-FCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVTSPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRKCLEETNWDFNHAAFVFEKLFKENKIPPEAFMK----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99257-1", "uniprot_id": "MEX67_YEAST", "id": "Q99257-1", "name": "mRNA export factor MEX67", "aln": "---------------------------------------------MSGFHNVGNINMMAQQQMQQNRIKISVRNWQNATMN---DLINFISRNARVAVYDAHVEG--------PLVIGYVNSKAEAESLMKWNGVRFAGSNLKFELLDNNG---------ASAGTSDTISFLRGVLLKRYDPQTKLLNLGALHSDPELIQKGVFSSISTQSKMFPAMMKLASTEKSLIVESVNLADNQLKDISAISTLAQTFPNLKNLCLANNQIFRFRSLEVWKNKFKDLRELLMTNNPITTDKLYRTEMLRLFPKLVVLDNVIVRDEQKLQTVYSLPMKIQQFFFENDALGQSSTDFATNFLNLWDNNREQLLNLYSPQSQFSVSVDSTIPPSTVTDSDQTPAFGYYMSSSRNISKVSS-EKSIQQRLSIGQESINSIFKTLPKTKHHLQEQPNEYSMETISYPQINGFVITLHGFFEETG--KPELESNKKTGKNNYQKNRRYNHGYNSTSNNKLSKKSFDRTWVIVPMNNSVIIASDLLTVRAYSTGAWKTASIAIAQPPQQQASVLPQVASMN--------------PNITTPPQPQPSVVPGGMSIPGAPQGAMVMAPTLQLPPDVQSRLNPVQLELLNKLH---------------------------------------------------------------LETKLNAEYTFMLAEQSNWNYEVAIKGFQSSMNG--IPREAFVQF---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::. : : :: * : . . : . : :: . . * .: : : .. .: : . . * .. .: :.. * .: : . . . : . . : : .. : .. .: : . ", "identical_positions": 4, "similar_positions": 57, "identity": "0.53%" }, { "cls_id": "homologset.agr.FB:FBgn0003326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43827-1", "uniprot_id": "ANGL7_HUMAN", "id": "O43827-1", "name": "Angiopoietin-related protein 7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKKPLSAVTWLCIFIVAFVSHP-----------AWLQKLSKHKTPAQPQLKAAN---------------------------------------------------------------------------CCEEVKELKA----------------QVANLSSLLSELNK--KQERDWVSVVMQVMELES-----------------------NSKR-----------------------------------------MESRLTD--------------------AESKYSEMNNQIDIMQLQAAQTVTQTSADAIY-------DCSSLYQKNYRISGVYKLPPD--DFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFG------------SIRGDFWLGNEHIHRLSRQ-PTRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVG-------------NDALQYHNNTAFSTKDKDND-----NCLDKCAQLRKGGYWYNCCTDSNLNGVY------YRLGEHNKHL--------------DGITWYGWHGSTYSLKRVEMKIRPEDFKP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K0E8-1", "uniprot_id": "FIBB_MOUSE", "id": "Q8K0E8-1", "name": "Fibrinogen beta chain", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRHLWLLLLLCVFSVQTQAADDDYDEPTDSLDARGHRPVDRRKEEPPSLRPAPPPISGGGYRARPAKA------------------------------TANQKKVERRPPDAGGCLHADTDMGVLCPTGCTLQQTLLN----------------QERPIKSSIAELNNNIQSVSDTSSVTFQYLTLLK-----------------------DMWKKKQAQVKENENVINEYSSILEDQRLYIDETVNDNIPLNLRVLRSILED--------------------LRSKIQKLESDISAQMEYCRTPCTVSCNIPVVS----GKECEEIIRKGGETSEMYLIQPD--TSIKP--YRVYCDMKTENGGWTVIQNRQDGSVDFGRKWDPYKKGFGNIATNEDAKKYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEASKYQVSVNKYKGTAGNALMDGASQLVGENRTMTIHNGMFFSTYDRDNDGWVTTDPRKQCSKEDGGGWWYNRCHAANPNGRY------YWGGLYSWDMSKHG--------TDDGVVWMNWKGSWYSMRRMSMKIRPFFPQQ-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y264-1", "uniprot_id": "ANGP4_HUMAN", "id": "Q9Y264-1", "name": "Angiopoietin-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSQLAMLQGSLLLVVATMSVAQQTRQEADRGCETLVVQHGHCSYTFLLPKSEPCPPGPEVSRDSNTLQRESLANPLHLGKLPTQQVKQLEQALQNNTQWLKKLERAIKTILRSKLEQVQQQMAQNQTAPMLELGTSLLNQTTA----------------QIRKLTDMEAQLLNQTSRMDAQMPETFLSTNKLE-----------------------NQLLLQRQKLQQLQGQNSALEKRLQALETKQQEELASILSKKAKLLNTLSRQSAALTNIERGLRGVRHNSSLLQDQQHSLRQLLVLLRHLVQERANASAPAFIMAGEQVFQDCAEIQRSGASASGVYTIQVS--NATKP--RKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKDYKQGFG------------DPAGEHWLGNEVVHQLTRRAAYSLRVELQDWEGHEAYAQYEHFHLGSENQLYRLSVVGYSGSAG-------------RQSSLVLQNTSFSTLDSDND-----HCLCKCAQVMSGGWWFDACGLSNLNGVY------YHAPDNKYKM--------------DGIRWHYFKGPSYSLRASRMMIRPLDI---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21520-1", "uniprot_id": "SCA_DROME", "id": "P21520-1", "name": "Protein scabrous", "aln": "MRDWQTFPDLQKKKVSRDHLNCPATMAGSNVLWPILLAVVLLQISVAFVSGAASGGVVLSDVNNMLRDAKVVTSEKPVVHSKQETEAPESSVELLRFVDDDEDSEDISSIERQDGRTMESKKMADQVRLLTKQLNALMLRRREDYEMLEHNLRKSLRLTTNANSVDADMRSELNQLREELAALRSSQSGNKERLTVEWLQQTISEIRKQLVDLQRTASNVAQDVQQRSSTFEDLATIRSDYQQLKLDLAAQRERQQQTEVYVQELREEMLQQEQDFQHALVKLQQRTRKDGSSASVEEESGSQEANQEQTGLETTADHKRRHCRFQSEQIHQLQLAQRNLRRQVNGLRFHHIDERVRSIEVEQHRIANANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKLEFANAQITSEQSLIREEGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQSLVNDEMKNKLTHLNKPHKRPHHQNVQAQMPQDDSPIDSVLAETLVSELENVETQYEAIINKLPHDCSEVHTQTDGLHLIAPAGQRHPLMTHCTADGWTTVQRRFDGSADFNRSWADYAQGFG------------APGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNAS--------------DALNYQQGMQFSAIDDDRD-----ISQTHCAANYEGGWWFSHCQHANLNGRYNLGLTWFDAARNEWIAVKSSRMLVKRLPAVECQANASASGAFVSVSGSAADAAPSSGATTTTTTATAAPATVTTPKTNNSVVQFVAAGQA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : : . :* . . : . : : : : .. . . : : : .. . . . . . . ** :*.* .* ..* *.* * :*** *:.*:**: : :*: * ::::* .. *.* * : .. . *:: : *.*... : :. **: * *.* :*: **:*:. * :* ** * : . : *. *: * ", "identical_positions": 43, "similar_positions": 80, "identity": "5.18%" }, { "cls_id": "homologset.agr.FB:FBgn0003330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLY4-1", "uniprot_id": "RING2_RAT", "id": "Q4KLY4-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKK------------------------------------------------------------------------QQIENGSG--AEDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGL--ELDNNNAAVAIDPVMDGAS-------EIELVFRPHPTLMEKD-------DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSK---------GESNQMN-------------------------LDTASEKQYTIYIATASGQFTVS--------ICQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQJ4-1", "uniprot_id": "RING2_MOUSE", "id": "Q9CQJ4-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKK------------------------------------------------------------------------QQIENGSG--AEDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGL--ELDNNNAAVAIDPVMDGAS-------EIELVFRPHPTLMEKD-------DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSK---------GESNQMN-------------------------LDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99496-1", "uniprot_id": "RING2_HUMAN", "id": "Q99496-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKK------------------------------------------------------------------------QQIENGSG--AEDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGL--ELDNNNAAMAIDPVMDGAS-------EIELVFRPHPTLMEKD-------DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSK---------GESNQMN-------------------------LDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803I4-1", "uniprot_id": "RING2_DANRE", "id": "Q803I4-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MTQTVQTNGVQPLSKTWELSLYELQRTPQEAITDGLEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARISKHNNQQALSHSIEEGLKIQAMNRLQRGKK------------------------------------------------------------------------HQIENGSG--AEDNGDSSHCSNASVHSNQEAGPSIKRTKT-----------------------SDDSGL--DMDNATENGGGDIALDGVS-------EIELVFRPHPTLMEKE-------DAAQTRYIKTSGNATVDHLSKYLAVRLALEEMRKN---------GEASPIN-------------------------VEAASEKQYTIYIPTASNQFTVLNGSFSLELVSEKYWKVNKPMELYFAPTKEHK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6MGB6-1", "uniprot_id": "RING1_RAT", "id": "Q6MGB6-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "--MTTPAN-AQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPMPG----------------------------------------------------------------SDQTTTMSGGEGEPGEGEGDGEDISSDSAP-DSAPGPAPKRPRGGGAGGSSVGTGGGAAGGACGGAGSEDSGD--RGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKG-------EYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQETVEPGGPGGGASDTGGPDGGGGERGVSGGGEGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35730-1", "uniprot_id": "RING1_MOUSE", "id": "O35730-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "--MTTPAN-AQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPMPG----------------------------------------------------------------SDQTATMSGGEGEPGEGEGDGEDVSSDSAP-DSAPGPAPKRPRGAGAGASSVGTGGGAAGGACGGAGSEDSGD--RGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKG-------EYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQETTEPGGPGGGASDTGGPDGGGGERGVAGGGEGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06587-1", "uniprot_id": "RING1_HUMAN", "id": "Q06587-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "--MTTPAN-AQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPG----------------------------------------------------------------SDQTTTMSGGEGEPGEGEGDGEDVSSDSAP-DSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGD--RGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKG-------EYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VB08-1", "uniprot_id": "RING1_DROME", "id": "Q9VB08-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "-----MTSLDPAPNKTWELSLYELQRKPQEVITDSTEIAVSPRSLHSELMCPICLDMLKKTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRADPNFDLLISKIYPSREEYEAIQEKVMAKFNQTQSQQALVNSINEGIKLQSQNRPQRFRTKGGGGGGGGGGNGNGAANVAAPPAPGAPTAVGRNASNQMHVHDTASNDSNSNTNSIDRENRDPGHSGTSAASAITSASNAAPSSSANSGASTSATRMQVDDASNPPSVRSTPSPVPSNSSSSKPKRAMSVLTSERSEESESDSQMDCRTEGDSNIDTEGEGNGELGINDEIELVFKPHPTEMSADNQLIRALKENCVRYIKTTANATVDHLSKYLAMRLTLDLGADLP-----------------------------------------EACRVLNFCIYVAPQPQQLVILNGNQTLHQVNDKFWKVNKPMEMYYSWKKT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .**********:*.***.* *. **.********************:************:***:************************.***** *********:**** *::*: ::.: :.**** **:**:::*: :* ** : . ... ... ... * :. ..*. *. *::* . ******:*** :. . .**:**:.************:*::*: . : :: **:.. :. : : ", "identical_positions": 143, "similar_positions": 71, "identity": "29.61%" }, { "cls_id": "homologset.agr.FB:FBgn0003334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRY6-1", "uniprot_id": "A0ABK0LRY6_RAT", "id": "A0ABK0LRY6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MIFPD-----------------------YFDWDKYLKETGSVSAPSEYFRQAKTPPTNEFQIGMKLEARDPRNIDSVCVASVIGITGARLRLRLDGGDNKNDFWRLVDSSDIQPVGTCEQEGDLLQPPLGYRMNASSWPMFLLRVLTGSELAPAVFFKKEPPRPPQNNFIVGMKIEAIDRKNPFMICPATIGAVSGDQVHITFDGWSGAFDYWCSYDSRDIFPVGWCRLTGDILQPPGKIRKLIPNYMFCHFRSDFDNVVFN---SIEAAEKTMSSVFTD-----------------------TLEDEDRTLKDFQAAPGWKKPKGRGFIKPGIDEARPGKHDQGAPAGKKSKGRGFTKTWEGETRPGRVVQVVPG--------------ECFFMFIS----------------------------------EKKRRGKTVTTPWSDQPRLFADQQAAPAEKKRKGKTVTTPWGDQPRLFTDPGAAPAEKKRKGKTITTPWTGQPRHFADQGTAPAEKKRKGKTITTPWSDQPRLFADQGAAPAEKKRKGTTVTTPWSDQPRLFADQGAAPAEKKRKGKTVTTPWGNQPRLFADQGAAPAEAKPKGRRVTKPRKDQDQFLADEEAMPALFSALSVSSTEKTPPSSSEQPKSSTSGKPKSSAFGKPKSSTSKGTQPSRKSPRKTS----VPKTSKKAGKTKSAGD-----TSASKKGITIKIVLP--KKRAGRNGKKEKIIPVVSSTSSASLSSLMRSS--SSNKTPE-----EPSKIVMSTVCVYINKHGDCGPYLDPQKVRQLPNHFGPGPVNVILRRTVQACVDCAIQPKDVFLFLKPDNRGGEMITAFFDGKVHTVQLPPVNSASFALRFLENFCRNLHCDKFLSSQPFRLKTHVHTSATNIDQSKPEN--EEPKG-KRSFKRLSSQPQP-SAPVSSKVPR---------------------------------KSG---------------------------------------------------RASKASSYIAVPDPSVLKQGFC----KDPSTWSVDEVIQFMKHTDPHISGPLADLFRQHVTY----LLIR---------------FSCCPNASK------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVB3-1", "uniprot_id": "B1AVB3_MOUSE", "id": "B1AVB3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MGQTANED-----------------------HFDWDKYLKETGSISAPSEYFRQSKTPPTNEFKIGMKLEARDPRNIDSVCVASVIGITGARLRLRLDGSDNKNDFWRLVDSSDIQPVGTCEQGGDLLQPPLGYTLNTSSWPMFLLRVLTGSELAPAVFFKEEPPRPLQNNFIVGMKIEAVDRKNPFMICPATIGAVCGDQLHITFDGWSGAFDYWCDYDSRDIFPVGWCRLTGDVLQPPGKIVEKRPRRKRRTRLWRLRTALLGNEEEAPAAEEPGTSVLTFGDENRTLKDCRGEAAEEPGTSAFTFGDENRTLKDCQG--GWKKPKGRGFIKPGKDETRPGKHDQGAPAGKKPRGRGFTQPLEDEARPGRDVQVAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGAAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGAAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKPKGKRVTKSRKDQAQFLADEEAMPALFSALSVSSTERTPPSSSEQPKSSTSGKTKS---------TSRGAQTSRKSPRKTSVVQPVPKTSKKAGKSKSTGN-----TSSPKKGITIKIVLP--KKKGGKSGKKEKSIPVISSTSSASLSTLMKSS--SSNKTSA-----GPSKIVMSTVCVYINKHGDCGPFLDPQKVQQLPNHFGPGPVNVILQRTVQACVNCAFQAKDVFLFLKTDNRGGEMITAFFDGKVHTVQLPPVNSASFALRFLENFCQSLQCDNFLSSQPFRREAQVPTPDTGTDQSKPEN--GEPKE-KRSLKRLSLHPHR-SAPVSSKVPR---------------------------------KSG---------------------------------------------------QASKASSYITVPDPSVLKQGFC----KDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHVTY----LLIR---------------FSCCPNASK------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQR0-1", "uniprot_id": "SCML2_HUMAN", "id": "Q9UQR0-1", "name": "Sex comb on midleg-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MGQTVNEDSMDVKKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVPIVKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAKTESSP---------------------------SEASQHSMQSPQKTTLILPTQQVRRSS-RIKPPGP-----TAVPKRSSSVKNITP--RKKGPNSGKKEKPLPVICSTSAASLKSLTRDRGMLYKDVAS-----GPCKIVMSTVCVYVNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGGEVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRGHTHSSAEHDKNQSAK--EDVTE-RQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGSAIPKEENLSEDSKSSSLNSGNYLNPACRNPMYIHTSVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQGFS----KDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B461-1", "uniprot_id": "A0A8M3B461_DANRE", "id": "A0A8M3B461-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MGKTHQKDKKHHKEKSGRNNEDSQPSQKLTEAFSWEMYLRETSSCPASPSCFRQSRVPPANDFRVGMKVEACDPRNASSWCIATVMGLMGVRLRLRLDGSDSTNDFWRLVDAADIQPIGTCEKSGDMLQPPLGFRMNASSWPMFLLKTLSGAEMAPSSAFKKEPPRPTQNFFKAGMKLEAVDRKNPYLICPATIGEVRGDKIFIMFDGWRGAFDYWCQFDSRDIFPVGWCQLTNHSLQPPGN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFTIPKTLLPSVSRPSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------SWRPMQSPYRLPHPLPPLPVRKG----------------VRGRRPKSQTIAMLKAAAEAAAAGNSPSQNGQSQP-----TSAHKSPISSPLTPKPYKKRGPKPGSKRKPK-VPHSLSSPILSSSVSDGRLSSLQTTR-----DSG--VVSTVCVYVNKHGNSGPHLDRKLLLQLPDHFGPGPVNTVLQHAVQACVDCAFQPKALFSFLQSQSDGGEIIRVRSEGGIHYVKLPTASSASFVLRFLETLCHHLQCDNLFSSQPFSPLTSSTHTPYERSKSVKEETSEALSV-ARGTRRFNRDSSAYSTALSPKLQRTEALPSDETIAHAENGASTEQQFLEESMDSASKSVAP------RPPAHRSTSEFHTPTGSSPHYPSHPPLLRGLSSNPAEPRTHRRVEGRLSASSTTGPDHQATEKDPSKTSNKSPSSWSIEEVMQFVRDADPQALGPHAELFRKHEIDGKALMLLRSDMIMKYMGLKLGPALKLCHHIEKLKQTK-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q96GD3-1", "uniprot_id": "SCMH1_HUMAN", "id": "Q96GD3-1", "name": "Polycomb protein SCMH1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MLVCYSVLACEILWDLPCSIMGSPLG-----HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKVVIPKNPYP----------------------------------------------------------------------------------------------------------------------------------------------------------------------ASDVNTEKPS---------------------------IHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHP-----ISAPSKT-AEPLKFP--KKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAAT---IPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQG-HGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFT-QTHLSLTAIEYSHSHDRYLPGETFV-LGNSLARSLEPHSDSMDSASNPTN---------------LVSTSQ-----RHRPLLSSCG------------------------LPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADPQLG-PHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQ----------------------------GKF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K214-1", "uniprot_id": "SCMH1_MOUSE", "id": "Q8K214-1", "name": "Polycomb protein SCMH1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MLVCYSVLACESLWDLPCSIMGSPLG-----HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGAEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKVVIPKNPSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------SSDVSTEKPS---------------------------IHS-TKTVLEHQPGQRGRKPGKKRGRTPKILIPHP-----TSTPSKS-AEPLKFP--KKRGPKPGSKRKPRTLLSPPPTSPTTSTPEPDTSTVPQDAAT---VPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQG-HGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFT-QTHLSLTATEYNHNHDRYLPGETFV-LGNSLARSLETHSDLMDSALKPAN---------------LVSTSQNLRTPGYRPLLPSCG------------------------LPLSTVSAVRRLCSKGVLKGKKERRDVESFWKLNHSPGSDRHLESRDPPRLSGRDPSSWTVEDVMQFVREADPQLG-SHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSFHIDRLKQVFWKRETILWSREGLSREVWPISEDTALGHFFSGMDKVFGSLSKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VHA0-1", "uniprot_id": "SCM_DROME", "id": "Q9VHA0-1", "name": "Polycomb protein Scm", "aln": "MSGGRDSSTSSGSNSAAPGASTNATSSASASASSTSTSASPGSTTSPASTQRQRGRPAKRATCTWCGEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSKGACTQCDNVIRDGAPNKEFCSIMCMNKHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFHVFDWDAYLEETGSEAAPAKCFKQAQNPPNNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEIFQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGHKSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSSSSKQRCPRP--------------------------------------------------------------------------------------------------------------------------------------------------------------------RYTVVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCMVTGPTYQTLAKLCLQEVLAASTDTQQLSKLLFALEGDVHIVTAAGKNFTVKIPSPMRMKDDESLAQFIETLCTTCRACANLISLVHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASS---------------------------TALAAGGVTAAKAATAPAGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESND-NSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKVNGRRNNLAL--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: **.** * .*. *:*: ** *:*::.**:** **** * *:*:*:*: * ********.*. ********:.:*:.:* **: *.:******: :*:**** :* : *..: :*. *: *** * * * * *:**:*:*** :** **:. : . :: : **** ******* : ******.*** : . :**** .. . : . : : * .. : : . . . ..* .: . .. . . : . .. : .: : * . : . : ..: . ..* : .** :. : : ..: . . : . . . . . . .* *::::*:*::. * : .:***:* :*:. :. . .: ", "identical_positions": 123, "similar_positions": 133, "identity": "9.33%" }, { "cls_id": "homologset.agr.FB:FBgn0003339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52949-1", "uniprot_id": "HXA5_RAT", "id": "P52949-1", "name": "Homeobox protein Hox-A5", "aln": "-----------------------------HNYGDHS-SVSEQFRDSASMHSGRYGYGYNGMDLSVGRS---GSGHFGS-GEXXR-------------------------------------------------SYXAGASAAPAEPRYSQPATSTHS-PPPDPLPCSAVAPLPGSD-THHGGKNSLGNSSG------CSANCGSTHISSREGVG---------TASAAEEDA-----------------------------------------------PASSEQAGAQSEPSPAPPAQ-----PQIYPWMRKLHISHDNI-GGPEGKRARTCYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09021-1", "uniprot_id": "HXA5_MOUSE", "id": "P09021-1", "name": "Homeobox protein Hox-A5", "aln": "-------MSSY-FVNSFCGRYPNGPDYQLHNYGDHS-SVSEQFRDSASMHSGRYGYGYNGMDLSVGRS---GSGHFGS-GERAR-------------------------------------------------SYAAGASAAPAEPRYSQPATSTHS-PPPDPLPCSAVAPSPGSD-SHHGGKNSLGNSSG------ASANAGSTHISSREGVG---------TASAAEEDA-----------------------------------------------PASSEQAGAQSEPSPAPPAQ-----PQIYPWMRKLHISHDNI-GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SMAAAGGAFRP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20719-1", "uniprot_id": "HXA5_HUMAN", "id": "P20719-1", "name": "Homeobox protein Hox-A5", "aln": "-------MSSY-FVNSFCGRYPNGPDYQLHNYGDHS-SVSEQFRDSASMHSGRYGYGYNGMDLSVGRS---GSGHFGS-GERAR-------------------------------------------------SYAASASAAPAEPRYSQPATSTHS-PQPDPLPCSAVAPSPGSD-SHHGGKNSLSNSSG------ASADAGSTHISSREGVG---------TASGAEEDA-----------------------------------------------PASSEQASAQSEPSPAPPAQ-----PQIYPWMRKLHISHDNI-GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SMAAAGGAFRP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGT6-1", "uniprot_id": "HXA5A_DANRE", "id": "Q9YGT6-1", "name": "Homeobox protein Hox-A5a", "aln": "-------MSSY-FVNSFCGRYPNGVDYPLHNYGDHN-S-SGQCRDSTGMHSGRYACGYNGMDLSTGHS---SPGHFLSSGERTQ-------------------------------------------------SYKDSPTATP--VRYNQPVTASSAEPSSDHLPCSSLANSPVSEQSHRALKISLSSTAG------SASKSFGTVLS-REGVSK--------VSSSMEEEK-----------------------------------------------PPGSGQTASQN-VSEAP---------QIYPWMRKLHISHDNL-AGPEGKRPRTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDNKLKSM-----NMAAAGSGYRP-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09013-1", "uniprot_id": "HXB5B_DANRE", "id": "P09013-1", "name": "Homeobox protein Hox-B5b", "aln": "-------MSSY-FLNSFSGRYPNGSDYQLLNYGTNG-AMNASYRDSTSMHSGSFGYNYNGIDLSVNR---PNNGHFGAVGDNSR-------------------------------------------------AFQNPS----QETRYRQ--SSCSL-SSPDPLSCATSDTLELK-GSSPPSDQSTPTGNSRLTNSNNLTSSNSTHFADTDETN---------VSSETEEG--------------------------------------------AQTTTTSHTQKQ-ESVATSTTTPN-DGQTPQIFPWMRKLHISHD-M-TGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SLATAGSAFQN-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09014-1", "uniprot_id": "HXB5A_DANRE", "id": "P09014-1", "name": "Homeobox protein Hox-B5a", "aln": "-------MSSY-FVNSFSGRYPNGPDYQLLNYGTSSSAMNASYRDSGTMHSGSYGYNYNGMDLSVNRS--TSTGHFGAVGDNSR-------------------------------------------------VFQSPA----PETRFRQP-SSCSL-ASPEPLPCSNSESLGPK-GSSPPSDQSTTTAG------NNLNSN--THFTEIDEAS---------ASSETEEASH-----------------------------------------RANNSAPRTQQKQ-ETTATSTTSATSDGQAPQIFPWMRKLHISHD-M-TGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SLATAGSAFQP-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09067-1", "uniprot_id": "HXB5_HUMAN", "id": "P09067-1", "name": "Homeobox protein Hox-B5", "aln": "-------MSSY-FVNSFSGRYPNGPDYQLLNYGSGS-SLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS-ASSSHFGAVGESSR-------------------------------------------------AFPAPA----QEPRFRQAASSCSL-SSPESLPCTNGDSHGAKPSASSPSDQATSASSS-------------ANFTEIDEAS---------ASSEPEEAA-------------------------------------------SQLSSPSLARAQPEPMATSTAAPE--GQTPQIFPWMRKLHISHD-M-TGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SLATAGSAFQP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09079-1", "uniprot_id": "HXB5_MOUSE", "id": "P09079-1", "name": "Homeobox protein Hox-B5", "aln": "-------MSSY-FVNSFSGRYPNGPDYQLLNYGSGS-SLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS-ASSSHFGAVGESSR-------------------------------------------------AFPASA----QEPRFRQATSSCSL-SSPESLPCTNGDSHGAKPSASSPSDQATPASSS-------------ANFTEIDEAS---------ASSEPEEAA-------------------------------------------SQLSSPSLARAQPEPMATSTAAPE--GQTPQIFPWMRKLHISHD-M-TGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SLATAGSAFQP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09074-1", "uniprot_id": "HXC5A_DANRE", "id": "P09074-1", "name": "Homeobox protein Hox-C5a", "aln": "-------MSSY-VGKSFSKQTQDASSCRMHTFDNYG--AHSEFHES--------NYAYEGLDLGGSFS-----SQIPTNSLRRE-------------------------------------------------AINTTDR-----------ARSSAAVQRTQSCSALGSRSFVSTHGYNPLSHGLLSQKAEG-------------NMEVMEKPSG--------KSSRRYQNG------------------------------------------------DYFSDKQQTNSTQRQNQSQ-----PQIYPWMTKLHMSHE-----SDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKLK----------VKGGL----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09077-1", "uniprot_id": "SCR_DROME", "id": "P09077-1", "name": "Homeotic protein Sex combs reduced", "aln": "MDPDCFAMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNN---SANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :* : . . . : : . . : . . : : . :* . **:*** ::*:. . : ** **.****************************: ***.*****************: ", "identical_positions": 60, "similar_positions": 32, "identity": "14.29%" }, { "cls_id": "homologset.agr.FB:FBgn0003345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99594-1", "uniprot_id": "TEAD3_HUMAN", "id": "Q99594-1", "name": "Transcriptional enhancer factor TEF-5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNSWNASSSP-GEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPP-LPPTLSSYEPLAPLP----SAAASVPVWQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYD-------KFPEKKGGLKELYEKGPPNAFFLVKFWADLN-STIQEGP--------GAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYR--IHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70210-1", "uniprot_id": "TEAD3_MOUSE", "id": "P70210-1", "name": "Transcriptional enhancer factor TEF-5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MASNSWTANSSP-GEAREDGSEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSSSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPP-LPPALNSYESLAPLPPAAASATASAPAWQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYD-------KFPEKKGGLKELYEKGPPNAFFLVKFWADLN-STIQEGP--------GAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYR--IHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A176-1", "uniprot_id": "A0A8I6A176_RAT", "id": "A0A8I6A176-1", "name": "", "aln": "MQLGGLARRGDCSGGFWMAGTRDTLGSLSYCPACARAQDLGAGNFGGKGGDALREAPPTPPHRPPPPRPGGWEARSVPGARAWPRRVPGCTPGAAGLEGLPPGLVSGVPFGLREPAGRGSTQALARARRCARCSRLRWDPARVSGSHGSGHPGGSGPEPRATSTIASNSWTANNSP-GEAREDGSEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVC---------------------SHLQVLARRKSREIQSKLKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTS-RFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPP-LPPTLNSYESLAPLPP-AAATAASVPAWQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYD-------KFPEKKGGLKELYEKGPPNAFFLVKFWADLN-STIQEGP--------GAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYR--IHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BDI4-1", "uniprot_id": "A0A8M2BDI4_DANRE", "id": "A0A8M2BDI4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARKKVREYQASIK----DQASKDKALQNMAALSSAQIVSPSLIKTSLPP---LPQSPYPPAARFWPTP--IPGQPGPSQDIKPFVNPYPNLSGP-VQSTISAYESLAPPPP---PVATAVPVWQDRTIASSKLRMLEYSAFMELPQDQDSYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYD-------KFPEKKGGLKELYEKGPQNAFFLVKFWADLNNSSVQDGP--------GSFYGVSSQYSSSENMTITVSTKVCSFGKQVVEKVETEYAHVDGGKCLYR--IHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRETQETLLCIAFVFEVSTSEHGAQYHVYRLIKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30051-1", "uniprot_id": "TEAD1_MOUSE", "id": "P30051-1", "name": "Transcriptional enhancer factor TEF-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPSSWSGSESP-AENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKSRDFHSKLK----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLP-GIPRPTFPGGPGFWPGM-IQTGQPGSSQDVKPFVQQAYPIQPA-VTAPIPGFEPTSAPAPS-------VPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYD-------KFPEKKGGLKELFGKGPQNAFFLVKFWADLN-CNIQDDA--------GAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYR--INRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28347-1", "uniprot_id": "TEAD1_HUMAN", "id": "P28347-1", "name": "Transcriptional enhancer factor TEF-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPSSWSGSESP-AENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKSRDFHSKLK----DQTAKDKALQHMAAMSSAQIVSATAIHNKLGLP-GIPRPTFPGAPGFWPGM-IQTGQPGSSQDVKPFVQQAYPIQPA-VTAPIPGFEPASAPAPS-------VPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYD-------KFPEKKGGLKELFGKGPQNAFFLVKFWADLN-CNIQDDA--------GAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYR--INRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K2N3-1", "uniprot_id": "A0A0G2K2N3_RAT", "id": "A0A0G2K2N3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------IEPSSWSGSESP-ADNMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLP-GIPRPTFPGGPGFWPGM-IQTGQPGSSQDVKPFVQQAYPIQPA-VTAPIPGFEPASAPAPS-------VPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYD-------KFPEKKGGLKELFGKGPQNAFFLVKFWADLN-CNIQDDA--------GAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYR--INRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BLW2-1", "uniprot_id": "A0A8M2BLW2_DANRE", "id": "A0A8M2BLW2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPSSWSGSESA-GEDIERMSDSADKPMDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKSREFHSKLK----DHTVKNDAINRMGGISSAQIVSATAIHSRLGLA-GLPRSALPGATGIWQ---VSTGQPGSSQDVKPFSQQNYPIQ---TTTAIAAYESPTALSAA-------VPPWHGRSIGTSKLRLVEFSAFLEHQRDPDLYNKHLFVHIGQTNYSYSDALLETVDIRQIYD-------KFPEKKGGLKELFGKGPQNAFFLVKFWADLN-CNIQEDS--------GSFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYK--ISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHIYRLVKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62296-1", "uniprot_id": "TEAD4_MOUSE", "id": "Q62296-1", "name": "Transcriptional enhancer factor TEF-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSNEWSSPDSPEGSSISGGSQALDKPIDNDAEGVWSPEIERSFQEALAIYPPCGRRKIILTEEGKMYGRNELIARHIKLRTGKTRTRKQVS---------------------SHIQVLARRKAREIQAKLK----DQAAKNKALQSMAAMSSAQIVSATAFHSKMALA-RGP--GYPAISGFWQG--ALPGQPGTSHDVKPFSQNTYPVQP---PLPLPGFESPAGPTPSP--SAPLAPPWQGRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQSSPSYSDPYLETVDIRQIYD-------KFPEKKGGLKELFERGPSNAFFLVKFWADLN-TNIDDEG--------SAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYR--IHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIX9-1", "uniprot_id": "A0A8I6AIX9_RAT", "id": "A0A8I6AIX9-1", "name": "Transcriptional enhancer factor TEF-3", "aln": "------------------------------------------------------------------------------MPLGDVGSWSAHSAHSYRAPLQTPAPGVGTASATRSGPEAVAAAGRLGPPRGLGAAGRALPPRLLNPGTGPTGAPPSRALEGKAGIITSNEWSSPDSPEGSSISGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKAREIQAKLK----DQAAKNKALQSMAAMSSAQIVSATTFHSKMALA-RGP--GYPAISGFWQG--ALPGQPGPSHDVKPFSQNTYAVQP---PLPLPGFESPVGPTPSP--SAPPAPPWQGRSIASSKLWMLEFSAFLERQQDPDTYSKHLFVHISQSSPSYSDPYLETVDIRQIYD-------KFPEKKGGLKELFERGPSNAFFLVKFWADLN-TNIDDQG--------SAFYGVSSQYESLENMIITCSTKVCSFGKQVVEKVETEFARYENGHYLYR--IHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15561-1", "uniprot_id": "TEAD4_HUMAN", "id": "Q15561-1", "name": "Transcriptional enhancer factor TEF-3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKAREIQAKLK----DQAAKDKALQSMAAMSSAQIISATAFHSSMALA-RGP--GRPAVSGFWQG--ALPGQAGTSHDVKPFSQQTYAVQP---PLPLPGFESPAGPAPSP--SAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYD-------KFPEKKGGLKDLFERGPSNAFFLVKFWADLN-TNIEDEG--------SSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYR--IHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48301-1", "uniprot_id": "TEAD2_MOUSE", "id": "P48301-1", "name": "Transcriptional enhancer factor TEF-4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGDPRTGAPLDDGGGWTGSEEG-SEEGTGGSEGVGGDGSPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKSREIQSKLK----DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPS----GPQATELFQFWSGS---SGPPWNVPDVKPFSQAPFSVSLTPPASDLPGYEPPPALSPLP-PPAPSPPAWQARALGTARLQLIEFSAFVEPPDAVDSFQRHLFVHISQQCPSPGAPPLESVDVRQIYD-------KFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSAEEAGSSG--GGGGFYGVSSQYESRELMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYR--LLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQYHIYRLVRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LAT8-1", "uniprot_id": "A0ABK0LAT8_RAT", "id": "A0ABK0LAT8-1", "name": "Transcriptional enhancer factor TEF-4", "aln": "-------------------------------------------MDSSLPKQAPRPECPREIPSLPPGPPPRSLPLFPNKAPGNFLRVSPRPPAAPLPRPGGRKAPAGIGILLGVCELGWEVPRDEVRRVFLRSRGKCTPSFFCPGARVCAGEAQMGDPRTGAPLDDGGGWTGSEEG-SEEGTGGSEGVGGDGSPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKSREIQSKLK----DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPS----GPQATELFQFWSGS---SGPTWNVPDVKPFSQAPFSMSLTPPATDLPGYEPPPALSPLP-PPAPSPPAWQARALGTARLQLVEFSAFVEPPDAVDSFQRHLFVHISQQCPSPGAPPLESVDVRQIYD-------KFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSAEEAGNSG--GAGGFYGVSSQYESRELMTLTCSSKVCSFGKQVVEKVETERAQLEGGRFVYR--LLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15562-1", "uniprot_id": "TEAD2_HUMAN", "id": "Q15562-1", "name": "Transcriptional enhancer factor TEF-4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGEPRAGAALDDGSGWTGSEEG-SEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKSREIQSKLK----DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPT----GPQASELFQFWSGG---SGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLP-PPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYD-------KFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYR--LLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30052-1", "uniprot_id": "SCAL_DROME", "id": "P30052-1", "name": "Protein scalloped", "aln": "----------------------------------------------------------------------------------------------------------MKNITSSSTCSTGLLQLQNNLSCSELEVAEKTEQQAVGPGTIPSPWTPVNAGPPGALGSADTNGSMVDSK-NLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVS---------------------SHIQVLARRKLREIQAKIK--------------------------VQFWQPGLQPS---------------------TSQDFYDYSIKPFPQPPYPAGKT--STAVSGDETGIPPSQLP---------WEGRAIATHKFRLLEFTAFMEIQRD-EIYHRHLFVQLGGK-PSFSDPLLETVDIRQIFD-------KFPEKSGGLKDLYEKGPQNAFYLVKCWADLN-TDLTTGS------ETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYR--IQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIKE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18412-1", "uniprot_id": "TEC1_YEAST", "id": "P18412-1", "name": "Ty transcription activator TEC1", "aln": "--------------------------------------------------------------------MSLKEDDFGKDNSRNIESYTGRIFDVYIQKDSYSQSALDDMFPEAVVSTAACVKNEAEDNINLIDTHPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNAN--FGRNELISLYIKHKTNEFRTKKQIS---------------------SHIQVWKKTIQNKIKDSLT-----LSSKEKELLHLIEHGAEQTTENSNLFYDIFEE--------------------IIDSLPSVSDSGSLTPKNLYVSNN--SSGLSVHSKLLTPITAS---------------NEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDRPNKASFSNKKAILESAKKIEIEQRKIINKYQRISRIQEHESNP------EFSSNSNSGSEYES-EEEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQYQTSYFSQLLLSSPQHYEHSPHQRN----------FTPSNQSHGNFY--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ** .:*.:* *** : * ** : : . :******: :** :*.: **:**:. **:** : .. : :. : . .: : . :: . : . : :*:: ::. . ** :. ::.: .*.:*.. *.. : : * . . . *:*.* : : *: * .: .: * :.: . .: : *.. * *::: * : *: : :*.. : . * : .. * : ", "identical_positions": 48, "similar_positions": 96, "identity": "7.45%" }, { "cls_id": "homologset.agr.FB:FBgn0003346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAA5-1", "uniprot_id": "F1MAA5_RAT", "id": "F1MAA5-1", "name": "Ran GTPase-activating protein 1", "aln": "MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSKLKR----CHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLTLKVFVAGRNRLENDGATALAEAFGIIGT-LEEVHMPQNGINHPGVTALAQA-FAINPLLRVINLNDNTFTEKGGVAMAETLKTLR-QVEVINFGDCLVRSKGAVAIADAVRGG-LPKLKELNLSFCEIKRD---AALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVLDSFNMAKVLASLSDDEGEDEDEDEEGE-DDEDEEDEE-------EEEE--EEEEEEEEEEEPQQRGSGEEPATPSRKILDPNSGEPAPVLSSPPPTDLSTFLSFPSPE----KLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDEASVKTAVLDAIDALMKKAFSSSSFN-SNTFLTRLLIHMGLLKSEDK-IKAIPSLHGPLMVLNHVVQQDYFPKTLAPLLLAFVTKPNGALESCSFARHSLLQTLYSI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46061-1", "uniprot_id": "RAGP1_MOUSE", "id": "P46061-1", "name": "Ran GTPase-activating protein 1", "aln": "MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKR----CHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGT-LEEVHMPQNGINHPGVTALAQA-FAINPLLRVINLNDNTFTEKGGVAMAETLKTLR-QVEVINFGDCLVRSKGAVAIADAVRGG-LPKLKELNLSFCEIKRD---AALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEE-------DEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPE----KLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFN-SNTFLTRLLIHMGLLKSEDK-IKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46060-1", "uniprot_id": "RAGP1_HUMAN", "id": "P46060-1", "name": "Ran GTPase-activating protein 1", "aln": "MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNTVGVEAARVIAKALEKKSELKR----CHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFRVIGT-LEEVHMPQNGINHPGITALAQA-FAVNPLLRVINLNDNTFTEKGAVAMAETLKTLR-QVEVINFGDCLVRSKGAVAIADAIRGG-LPKLKELNLSFCEIKRD---AALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDD--EDEEEEEEGEEEEEEAEEEE-------EEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPPPADVSTFLAFPSPE----KLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEATVRMAVQDAVDALMQKAFNSSSFN-SNTFLTRLLVHMGLLKSEDK-VKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5B1-1", "uniprot_id": "A0ACD6B5B1_DANRE", "id": "A0ACD6B5B1-1", "name": "Ran GTPase-activating protein 1", "aln": "MALGDIAQITEALAKTHVGEVELSYKGRGLKLDNAESVKEIVEDIERCQGLQSLRLEGNTLGVEAADAIAKSLEAKRELEQ----CHWSDMFTGRLRSEIPPALKSLGNALMTSGARLTQLDLSDNAFGPDGVKGIENLLKSSACYTLQELRLNNCGMGSGGGVVLASALTECHKQSSAAASPLRLKVFIAGRNRLENDGATALAKAFKLLGS-LEEVHMPQNGINHPGITALAAA-LKHNPNLQVLNLNDNTFTTKGSKAMAEAIRHLQ-CLKAINFGDCLVRSEGAIAIAGALREG-LHLLRELNLSFGEICEA---AAMVVAKAVQGKADLEKLDLNGNCFGEDGCEALKEAMEKMNMEDLLCSLSDDEGEPDEEDNDDDDDDDDEEEDE-------DDDDDAEEKEGNDAEENGLNG---------TKDVIEEKE-------EPPHSSELMSFLVSPSAE----KLISLGAKRVQLIEQQVDVTDANKVSEVFLKISSVYKDEPEVKQAVFETTDALLRKAFSNSPHSQSYSFISSLMVNLGLLKSEDKKVKKVSVLPGHLLTLEHAVSQEFFPADQAGVLESFVSRNGAVLESCCSARDALKITLVKRTTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIW3-1", "uniprot_id": "RAGP1_DROME", "id": "Q9VIW3-1", "name": "Ran GTPase-activating protein", "aln": "MSTFNFASMAAQLGQEQG----ISFENKVLSWNTAADVQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKRHPEFRK----ALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKT-FEEIVLEQNSIYIEGVEALAES-FKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLP-LLREMSFGDCLIKTNGAYHFGEALERG-NERLEVIDLGFNEINSD---GGLVLVNAMGNKPKLRILNLDGNSFGEEGSEKIISEMSKLPTAAALQPFQHQEEEDLEDEYQADKQDADYEEEEEVHEHANDTTEEADEDSEGDEDDEEDEGDEEYSNVAEETAYVTTNAYTTKLFNDTTNSMASETFAVANKTISQKCTPEKFCLSQKPCSQEDFDSLDMDNKLEALQSIVNQFTGDNHLLLLVFTTLKCAHLSQSSKAALDLAVSLYQATFDYAIKTKQETR-VLNYVLMQLRLLPCKEVFHSDYDVKNCRFALREALKQPTFANDNIKNSFKTFLEGAES----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11745-1", "uniprot_id": "RNA1_YEAST", "id": "P11745-1", "name": "Ran GTPase-activating protein 1", "aln": "MATLHFVPQHEEEQ-------VYSISGKALKLTTSDDIKPYLEELAALKTCTKLDLSGNTIGTEASEALAKCIAENTQVRESLVEVNFADLYTSRLVDEVVDSLKFLLPVLLKC-PHLEIVNLSDNAFGLRTIELLEDYIAHAVN--IKHLILSNNGMGPFAGERIGKALFHLAQNKKAASKPF-LETFICGRNRLENGSAVYLALGLKSHSEGLKVVKLYQNGIRPKGVATLIHYGLQYLKNLEILDLQDNTFTKHASLILAKALPTWKDSLFELNLNDCLLKTAGSDEVFKVFTEVKFPNLHVLKFEYNEMAQETIEVSFLPAMEKGNLPELEKLEINGNRLDEDS-----------DALDLLQSKFDDLEVDDFEEVDSEDEEGEDEEDE-------------DEDEKLEEIETER-------------------------------------------------------------LEKELLEVQVDDLAERLAETEIK-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:. * ..: *. .: . : :. : * *.***:*.**: .:.: : : :... : :::*.** *: :* * *: . .:* ::*****:* :. :* : .. ::.* * * *:* .* :. ** . : . . *: *..*: .*****: .*. :* .: :: : : **.* *: :* : *.:::::***:. ... :*::: : :.:.***::: *: . .. *. :.: : *: .: . . ..*. *:::** :.*:. * . .: :: : : :: : *::* :*.. : : :: : :. . : . ", "identical_positions": 69, "similar_positions": 151, "identity": "11.2%" }, { "cls_id": "homologset.agr.FB:FBgn0003356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR35-1", "uniprot_id": "CTRB1_MOUSE", "id": "Q9CR35-1", "name": "Chymotrypsinogen B", "aln": "--MAFLWLVSCFALVGATFGCGVPAIQPVLTGLSRIVNGEDAIPGSWPWQVSLQDRTG---FHFCGGSLISENWVVTAAHCGVKT-TDVVVAGEFDQGSDEENVQVLKIAQ--VFKNPKFNSFTVR--NDITLLKLATPAQFSETVSAVCLPTVDDDFP--AGTLCATTGWGKTKYNALKTPDKLQQAALPIVSEAKCKES--WGSKITDVMICAGASGVS--------------SCMGDSGGPLVCQK-DGVWTLAGIVSWGS--GFCSTSTPAVYARVTALMPWVQEILEAN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07338-1", "uniprot_id": "CTRB1_RAT", "id": "P07338-1", "name": "Chymotrypsinogen B", "aln": "--MAFLWLVSCFALVGATFGCGVPTIQPVLTGLSRIVNGEDAIPGSWPWQVSLQDKTG---FHFCGGSLISEDWVVTAAHCGVKT-SDVVVAGEFDQGSDEENIQVLKIAQ--VFKNPKFNMFTVR--NDITLLKLATPAQFSETVSAVCLPNVDDDFP--PGTVCATTGWGKTKYNALKTPEKLQQAALPIVSEADCKKS--WGSKITDVMTCAGASGVS--------------SCMGDSGGPLVCQK-DGVWTLAGIVSWGS--GVCSTSTPAVYSRVTALMPWVQQILEAN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05208-1", "uniprot_id": "CEL2A_MOUSE", "id": "P05208-1", "name": "Chymotrypsin-like elastase family member 2A", "aln": "----MIRTLLLSALVAGALSCGYPTYEVEDD-VSRVVGGQEATPNTWPWQVSLQVLSSGRWRHNCGGSLVANNWVLTAAHCLSNYQTYRVLLGAHSLSNPGAGSAAVQVSK--LVVHQRWNSQNVGNGYDIALIKLASPVTLSKNIQTACLPPAGTILP--RNYVCYVTGWGLLQTNGN-SPDTLRQGRLLVVDYATCSSASWWGSSVKSSMVCAGGDGVT-------------SSCNGDSGGPLNCRASNGQWQVHGIVSFGSSLGCNYPRKPSVFTRVSNYIDWINSVMARN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00774-1", "uniprot_id": "CEL2A_RAT", "id": "P00774-1", "name": "Chymotrypsin-like elastase family member 2A", "aln": "----MIRTLLLSALVAGALSCGYPTYEVQHD-VSRVVGGQEASPNSWPWQVSLQYLSSGKWHHTCGGSLVANNWVLTAAHCISNSRTYRVLLGRHSLSTSESGSLAVQVSK--LVVHEKWNAQKLSNGNDIALVKLASPVALTSKIQTACLPPAGTILP--NNYPCYVTGWGRLQTNGA-TPDVLQQGRLLVVDYATCSSASWWGSSVKTNMVCAGGDGVT-------------SSCNGDSGGPLNCQASNGQWQVHGIVSFGSTLGCNYPRKPSVFTRVSNYIDWINSVIAKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZFG3-1", "uniprot_id": "D3ZFG3_RAT", "id": "D3ZFG3-1", "name": "", "aln": "----MLRLLCSLLLVALASGCGQPSYNPS----SRVVNGEDAVPYSWPWQVSLQYEKDGSFHHTCGGTLIAPDWVMTAGHCISTSRTYQVVLGEFERGVEEGPEQVIPVNAGDLFVHPKWNSNCVSCGNDIALVKLSRSAQLGDTVQLACLPPAGEILP--NGAPCYISGWGRLSTNGP-LPDKLQQALLPVVDYAHCSKWDWWGFSVKKTMVCAGGDIQARSLSSDTPYPLLFSSLQGDSGGPLNCPAENGTWQVHGVTSFVSSLGCNTLKKPTVFTRVSAFNEWIEETIANN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKF7-1", "uniprot_id": "SER1_DROME", "id": "C0HKF7-1", "name": "Serine protease 1", "aln": "MKLFVFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNG--NWWCGGSIIGNTWVLTAAHCTNGASGVTINYGAS---IRTQPQYTHWVGSGDIIQHHHYNSGNLH--NDISLIRTP-HVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSP-LPDWLQSVDVQIISQSDCSRT----WSLHDNMICINTDGGK-------------STCGGDSGGPLVTHD---GNRLVGVTSFGSAAGCQSG-APAVFSRVTGYLDWIRDNTGISY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : .. . . : .*:..* * . *: *.* . ***:::. **:**.** : * . : :. : ::* : **:*:: . . : . :. . ** . . . :*** .. *: *:. : ::. : *. .: * * . . : ******* : *:.*: * * *:*::**: *:.. . ", "identical_positions": 46, "similar_positions": 73, "identity": "15.59%" }, { "cls_id": "homologset.agr.FB:FBgn0003357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR35-1", "uniprot_id": "CTRB1_MOUSE", "id": "Q9CR35-1", "name": "Chymotrypsinogen B", "aln": "--MAFLWLVSCFALVGATFGCGVPAIQPVLTGLSRIVNGEDAIPGSWPWQVSLQDRTG---FHFCGGSLISENWVVTAAHCGVKT-TDVVVAGEFDQGSDEENVQVLKIAQ--VFKNPKFNSFTVR--NDITLLKLATPAQFSETVSAVCLPTVDDDFP--AGTLCATTGWGKTKYNALKTPDKLQQAALPIVSEAKCKES--WGSKITDVMICAGASGVS--------------SCMGDSGGPLVCQK-DGVWTLAGIVSWGS--GFCSTSTPAVYARVTALMPWVQEILEAN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07338-1", "uniprot_id": "CTRB1_RAT", "id": "P07338-1", "name": "Chymotrypsinogen B", "aln": "--MAFLWLVSCFALVGATFGCGVPTIQPVLTGLSRIVNGEDAIPGSWPWQVSLQDKTG---FHFCGGSLISEDWVVTAAHCGVKT-SDVVVAGEFDQGSDEENIQVLKIAQ--VFKNPKFNMFTVR--NDITLLKLATPAQFSETVSAVCLPNVDDDFP--PGTVCATTGWGKTKYNALKTPEKLQQAALPIVSEADCKKS--WGSKITDVMTCAGASGVS--------------SCMGDSGGPLVCQK-DGVWTLAGIVSWGS--GVCSTSTPAVYSRVTALMPWVQQILEAN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05208-1", "uniprot_id": "CEL2A_MOUSE", "id": "P05208-1", "name": "Chymotrypsin-like elastase family member 2A", "aln": "----MIRTLLLSALVAGALSCGYPTYEVEDD-VSRVVGGQEATPNTWPWQVSLQVLSSGRWRHNCGGSLVANNWVLTAAHCLSNYQTYRVLLGAHSLSNPGAGSAAVQVSK--LVVHQRWNSQNVGNGYDIALIKLASPVTLSKNIQTACLPPAGTILP--RNYVCYVTGWGLLQTNGN-SPDTLRQGRLLVVDYATCSSASWWGSSVKSSMVCAGGDGVT-------------SSCNGDSGGPLNCRASNGQWQVHGIVSFGSSLGCNYPRKPSVFTRVSNYIDWINSVMARN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00774-1", "uniprot_id": "CEL2A_RAT", "id": "P00774-1", "name": "Chymotrypsin-like elastase family member 2A", "aln": "----MIRTLLLSALVAGALSCGYPTYEVQHD-VSRVVGGQEASPNSWPWQVSLQYLSSGKWHHTCGGSLVANNWVLTAAHCISNSRTYRVLLGRHSLSTSESGSLAVQVSK--LVVHEKWNAQKLSNGNDIALVKLASPVALTSKIQTACLPPAGTILP--NNYPCYVTGWGRLQTNGA-TPDVLQQGRLLVVDYATCSSASWWGSSVKTNMVCAGGDGVT-------------SSCNGDSGGPLNCQASNGQWQVHGIVSFGSTLGCNYPRKPSVFTRVSNYIDWINSVIAKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZFG3-1", "uniprot_id": "D3ZFG3_RAT", "id": "D3ZFG3-1", "name": "", "aln": "----MLRLLCSLLLVALASGCGQPSYNPS----SRVVNGEDAVPYSWPWQVSLQYEKDGSFHHTCGGTLIAPDWVMTAGHCISTSRTYQVVLGEFERGVEEGPEQVIPVNAGDLFVHPKWNSNCVSCGNDIALVKLSRSAQLGDTVQLACLPPAGEILP--NGAPCYISGWGRLSTNGP-LPDKLQQALLPVVDYAHCSKWDWWGFSVKKTMVCAGGDIQARSLSSDTPYPLLFSSLQGDSGGPLNCPAENGTWQVHGVTSFVSSLGCNTLKKPTVFTRVSAFNEWIEETIANN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKF8-1", "uniprot_id": "SER2_DROME", "id": "C0HKF8-1", "name": "Serine protease 2", "aln": "MKLFVFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNG--NWWCGGSIIGNTWVLTAAHCTNGASGVTINYGAS---IRTQPQYTHWVGSGDIIQHHHYNSGNLH--NDISLIRTP-HVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSP-LPDWLQSVDVQIISQSDCSRT----WSLHDNMICINTDGGK-------------STCGGDSGGPLVTHD---GNRLVGVTSFGSAAGCQSG-APAVFSRVTGYLDWIRDNTGISY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : .. . . : .*:..* * . *: *.* . ***:::. **:**.** : * . : :. : ::* : **:*:: . . : . :. . ** . . . :*** .. *: *:. : ::. : *. .: * * . . : ******* : *:.*: * * *:*::**: *:.. . ", "identical_positions": 46, "similar_positions": 73, "identity": "15.59%" }, { "cls_id": "homologset.agr.FB:FBgn0003360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51881-1", "uniprot_id": "ADT2_MOUSE", "id": "P51881-1", "name": "ADP/ATP translocase 2", "aln": "-------------MTD--AAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQH-ASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KAGAE-REFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09073-1", "uniprot_id": "ADT2_RAT", "id": "Q09073-1", "name": "ADP/ATP translocase 2", "aln": "-------------MTD--AAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQH-ASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KAGAE-REFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05141-1", "uniprot_id": "ADT2_HUMAN", "id": "P05141-1", "name": "ADP/ATP translocase 2", "aln": "-------------MTD--AAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQH-ASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KAGAE-REFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12236-1", "uniprot_id": "ADT3_HUMAN", "id": "P12236-1", "name": "ADP/ATP translocase 3", "aln": "-------------MTE--QAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQH-ASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KSGTE-REFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48962-1", "uniprot_id": "ADT1_MOUSE", "id": "P48962-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--QALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQH-ASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGSSQ-REFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05962-1", "uniprot_id": "ADT1_RAT", "id": "Q05962-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--QALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQH-ASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGSSQ-REFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGRKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12235-1", "uniprot_id": "ADT1_HUMAN", "id": "P12235-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--HAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQH-ASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGAAQ-REFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEI2-1", "uniprot_id": "A0A8M1NEI2_DANRE", "id": "A0A8M1NEI2-1", "name": "ADP/ATP translocase", "aln": "-------------MSD--SVVSFAKDFLAGGVAAAVSETAVAPIERVKLLLQVQH-ASKQITTDKQYKGIVDCVVRIPREQGFLSFWRGNLANVIRYFLTQALNFAFKDKYRRIFLDGVDQRTQFWRYFAGNLAAGGAAGATSLCLVYPLDFARTRLAADVG--KTGTAGREFKGLANCLVKIYRSDGVRGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PENTHIAVSWMIAHTVTIVAGFISYPFDTVRRSMMMQSGLKGADVMYSGSIDCWRKIARNEGPKAFFKGAWSNVLRSLGGSIVLVLYDEFKKVI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q26365-1", "uniprot_id": "ADT_DROME", "id": "Q26365-1", "name": "ADP/ATP translocase", "aln": "MGNISASITSQSKMGKDFDAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQH-ISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADTG--KGGQR--EFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPD-PKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18238-1", "uniprot_id": "ADT3_YEAST", "id": "P18238-1", "name": "ADP/ATP translocase 3", "aln": "MSSDAK-----------QQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKE--EGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGA-RQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18239-1", "uniprot_id": "ADT2_YEAST", "id": "P18239-1", "name": "ADP/ATP translocase 2", "aln": "MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKE--EGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGA-RQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04710-1", "uniprot_id": "ADT1_YEAST", "id": "P04710-1", "name": "ADP/ATP translocase 1", "aln": "MSHTET----------QTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRER-DGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQ-RQFNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSFVASFLLGWVITMGASTASYPLDTVRRRMMMTSG---QTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* **::**:::*..:******:*:* *. ** : : :* *::**. * . .:*. ****** ***:*** *********** : :: : : :***** :*****. ** :**.**:******** * :* ** : * ::**: ***:** ** **::**. ***.:*: : :: . : : *: :. :* *. ***:***** *** ** : * .:..* .* ** ::***. :*::*. ..: *: :**::: ", "identical_positions": 122, "similar_positions": 79, "identity": "37.65%" }, { "cls_id": "homologset.agr.FB:FBgn0003366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63132-1", "uniprot_id": "ROS1_RAT", "id": "Q63132-1", "name": "Proto-oncogene tyrosine-protein kinase ROS", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRIRWLTPKPATFVVLGC-VWISVAQGTILSSCLTSCVTNLGRQLDSGTRYNLSEACIQGCQFWNSIDQEKCALKCNDTYVTICERESCEVGCSNAEGSYEEEVLDNTELPTAPFASSIG--------SNGVTLRWNPAN----ISGVKYIIQWKYAQLPGSWAYTETVSK-----------------------LSYMVEPLHPFTEYIFRVVWIFTAQLH--LYSPPSPSYRTHPYGVPETAPFITNIESSSPDTVEVSWAPPYFPGGPILGYNLRLISKTQKLDSGTQRTSFQ----FYSTLPNTTYRFSIAAVNEVGEGPEAESMITTPSPAVQEEEQWLFLSRKTSLRKRS-LKYLVDEAHCLWSDAIRHNITGISVNTQQEVVYFS----EGTIIWMKGAANMSDVSDLRIFYR----GSALVSSISVDWLYQRMYFIMDNRVHVCDLKHCSN-------LEEITPFSIVAPQKVVVDSYNGYVFYLLRDGIYRVHLPLPSVRDTKAVRIVESGTLKDFAVKPQSKRIIYFNGTMQVFMSTFLDGSAFHRVLPWVPLADVK---------SFACENNDFLITDGKAIFQQDSLS----FNEFIVGCDLSHIEEFGFGNLVIFGSSVQSYPLPGHPQEVSVLFGSREALIQWKPPI----LAIGA--------------SPSAWQNWTYEVKVSSQDILETTQVFLNISRTVLNVPKLQSSTKYMVSVRASSPKGPGPWSEPSVGTTLVPATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHISSIAGACALAFEWLGHFLYWAGKT-YVIQRQSVLTGHTDIVTHVKLLVNDMAVDPVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGADATITEFAAWSTSEISQNALMYYSGRLFWINGF-RIITAQEIGQRTSVSVSEPGKFNQFTIIQTSLKPLPGNFSSTPTVIPDSVQESSFRIEGHTSSFRILWNEPPAVDWGIVFYSVEFSAHSKFLAIEQQSLPVFTVEGLEPYALFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSLGRYTRKNEVVVEFRWNKPKHENGVLTKSEIFYHISKQSGTNKSTEDWVSVSVTPPVMSFQLEAMSPGYIVSFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLISLLGNKIEFLDMDQNQVVWTFSLEGAVSTVGYTADDEMGYFAQGDALFLLNLHNHSSSKLFQDVLASDIAVIAVDWIARHLYFALKASQDGTQIFDVDLEHKVKSPREVKICKSHTAIISFSMYPLLSRLYWTEVSDLGYQMFYCNISSHTLHHVLQPKASNQHG-RRQCSCNVTESELSGAMTVDTSDPDRPWIYFTKQQEIWAMDLEGCQCWKVIMVPATPG-KRIISLTVDGEFIYWITTMKDDTEIYQAKKGSGAILSQVKAPRSKHILAYSSALQPFPDKAYLSVASNMVEASILNATNTSLILKLPPVKTNLTWHGITTPTSTYLVYYMEAN-RANSSDRKHNMLESQENVARIEGLQPFSTYVIQIAVKNYYSDPLEHLSLGKEIQGKTKSGVPGAVCHINATVLSDTSLLVFWTESHKPNGPKELVRYQLVMSYLAPIPETPLRQDEFPSARLSLLVTKLSGGQQYVLKILACHSEEMWCTESHPVSVNMFDTPEKPSALVPENTSLLLDWKAPSNANLTRFWFELQKWKYSEFYHVKASCSQGPVYVCNIANLQPYTPYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPKLLEGSKNSI--QWEKAEDNGNRLMYYTLEVRKSISNDSRDQSLRWT----------------------AVFNGSCSSICTWRSKNLKGTFQFRAVASNAIGFGEYSEISEDITLVEDGFWITETSFILTIIVGIFLVATVPLTFVWHRSLK--NHKATKEGLSVLNDNDQELAELRGLAAGVGLANACYAVHTLPTQEEIESLPAFPREKLSLRLLLGSGAFGEVYEGTAVDILGRGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGP----LLTLADLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSP--RVVKIGDFGLAREIYKHDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRNVSLNNVSHCGQAAPAGGVINKGFEGEDNEMAT-LNSDDTMPVALMETRNQEGLNYMVLATKCSQSEDRYEGPLGSKESGLHDLKKDERQP-ADKDFCQQPQVAYGSPGHSEGLNYACLAHSGHGDVSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78DX7-1", "uniprot_id": "ROS1_MOUSE", "id": "Q78DX7-1", "name": "Proto-oncogene tyrosine-protein kinase ROS", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNICWLTLKLVKFVVLGCIIWISVAQSTVLSSCLTSCVTNLGRQLDSGTRYNLSEACIHGCQFWNSVDQETCALKCNDTYATICERESCEVGCSNAEGSYEEEVLESTELPTAPFASSIG--------SHGVTLRWNPAN----ISGVKYIIQWKYAQLPGSWTFTETVSK-----------------------LSYTVEPLHPFTEYIFRVVWIFTAQLH--LYSPPSPSYRTHPYGVPETAPLILNMESWSPDTVEVSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQ----FYSTLPNTTYRFSIAAVNEVGEGPEAESTVTTPSPSVQEEEQWLFLSRKTSLRKRS-LKYLVDEAHCLWSDAIHHNITGISVYAQQQVVYFS----EGTVIWMKGAANMSDVSDLRIFYQ----GSGLVSSISIDWLYQRMYFIMDKLVYVCELKNCSN-------LEEITPFSLIAPQKVVVDSYNGYLFYLLRDGIYRVNLPLPSGRDTKAVRIVESGTLKDFAVKPQSKRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLVTVK---------SFACENNDFLITDGKAIFQQDSLS----FNEFIVGCDLSHIEEFGFGNLVIFGSSVQSYPLPGHPQEVSVLFGSREALIQWTPPA----LAIGA--------------SPSAWQNWTYEVKVYSQDILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVGTTLVPATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHIPSIVGAGALAFEWLGHFLYWAGKT-YVIQRQSVLTGHTDIVTHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGGDATITEFAAWSTSEISQNALMYYSGRLFWINGF-RIITAQEIGQRTSVSVSEPAKFNQFTIIQTSLKPLPGNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSKFLIIEQQSLPIFTVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSSGRYTKKNEVVVEFRWNKPKHENGVLTKFEIFYHISKQSGTNRSTEDWMSASVIPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSLEGDVSTVGYTTDDEMGYFAQGDTLFLLNLRNHSSSKLFQDALVSDIRVIAVDWIARHLYFALKASQNGTQIFNVDLEHKVKSPREVKTCKAHTTIISFSIYPLLSRLYWTEVSDLGHQMFYCNISNHTSQHVLQPKASNQHG-RSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKRQEIWAMDLEGCQCWKVIMVPTIPG-KRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKHILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTWHGITHPTSTYLIYYMEAN-RANSSDRRHKMLESQENVARIEGLQPFSMYMIQIAVKNYYSEPLEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSYLAPIPETPLRQGEFPSAKLSLLITKLSGGQLYVMKVLACHPEEMWCTESHPVSVNMFDTPEKPSALVPENTSLQLDWKARSNVNLTGFWFELQKWKYNEFYHVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPKLLEGSKNSI--QWEKAEDNGSRLMYYTLEVRKGISNDSQNQSSRWK----------------------VVFNGSCSSICTWRSKNLKGTFQFRAVAANEIGLGEYSEISEDITLVEDGVWITETSFILTIIVGIFLVATVPLTFVWHRSLK--SHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIENLPAFPREKLSLRLLLGSGAFGEVYEGTAIDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGP----SLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSP--RVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSHCGEAAPTGGVINKGFEGEDDEMVT-LNSDDTMPVALMETKNQEGLNYMVLATKCSQGEGSYEGPLGPKELGSCDLKKDKKQPQADKDFCQEPQVAYGSPGLSEGLNYACLAHSEHGDVSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08922-1", "uniprot_id": "ROS1_HUMAN", "id": "P08922-1", "name": "Proto-oncogene tyrosine-protein kinase ROS", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNIYCLIPKLVNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHNLSEPCIQGCHFWNSVDQKNCALKC---------RESCEVGCSSAEGAYEEEVLENADLPTAPFASSIG--------SHNMTLRWKSAN----FSGVKYIIQWKYAQLLGSWTYTKTVSR-----------------------PSYVVKPLHPFTEYIFRVVWIFTAQLQ--LYSPPSPSYRTHPHGVPETAPLIRNIESSSPDTVEVSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQ----FYSTLPNTIYRFSIAAVNEVGEGPEAESSITTSSSAVQQEEQWLFLSRKTSLRKRS-LKHLVDEAHCLRLDAIYHNITGISVDVHQQIVYFS----EGTLIWAKKAANMSDVSDLRIFYR----GSGLISSISIDWLYQRMYFIMDELVCVCDLENCSN-------IEEITPPSISAPQKIVADSYNGYVFYLLRDGIYRADLPVPSGRCAEAVRIVESCTLKDFAIKPQAKRIIYFNDTAQVFMSTFLDGSASHLILPRIPFADVK---------SFACENNDFLVTDGKVIFQQDALS----FNEFIVGCDLSHIEEFGFGNLVIFGSSSQLHPLPGRPQELSVLFGSHQALVQWKPPA----LAIGANVILISDIIELFELGPSAWQNWTYEVKVSTQDPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVGTTLVPASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTKGDVFVWLLNGTDISENYHLPSIAGAGALAFEWLGHFLYWAGKT-YVIQRQSVLTGHTDIVTHVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQTQPWFSGKKVIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQSTGDTTITEFAAWSTSEISQNALMYYSGRLFWINGF-RIITTQEIGQKTSVSVLEPARFNQFTIIQTSLKPLPGNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSKFLASEQHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPETVPSAPENPRIFILPSGKCCNKNEVVVEFRWNKPKHENGVLTKFEIFYNISNQSITNKTCEDWIAVNVTPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPYADVVKSTTSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYTADNEMGYYAEGDSLFLLHLHNRSSSELFQDSLVFDITVITIDWISRHLYFALKESQNGMQVFDVDLEHKVKYPREVKIHNRNSTIISFSVYPLLSRLYWTEVSNFGYQMFYYSIISHTLHRILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKAQEIWAMDLEGCQCWRVITVPAMLAGKTLVSLTVDGDLIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRHILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTWYGITSPTPTYLVYYAEVNDRKNSSDLKYRILEFQDSIALIEDLQPFSTYMIQIAVKNYYSDPLEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISHLALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLKVLACHSEEMWCTESHPVTVEMFNTPEKPYSLVPENTSLQFNWKAPLNVNLIRFWVELQKWKYNEFYHVKTSCSQGPAYVCNITNLQPYTSYNVRVVVVYKTGENSTSLPESFKTKAGVPNKPGIPKLLEGSKNSI--QWEKAEDNGCRITYYILEIRKSTSNNLQNQNLRWK----------------------MTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLK--NQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGP----LLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSP--RIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVIC-LNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGYGDGSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HQU1-1", "uniprot_id": "A0AC58HQU1_DANRE", "id": "A0AC58HQU1-1", "name": "Tyrosine-protein kinase receptor", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGSELKCQTPRSGFKQCS--------------------------NAICQN----------------VACEL--------------------AAPYASWIG--------SHSISLTWESLN----QSDVVFVPQWTSPSLSGIWAQAENVTE-----------------------SSYTVEQLEPYTYYTFR-VWAVIAETQ--ACSPASPWYQTKPFGLPS-SPSIENVESISGESVEVRWTPPEKPRGPILGFNLNLTSNKHKISAATGGNVFSN--TFYPTFHNTTYRISIAAVNEEGQGSVAEASITTPAQVGQDGGRWVFASRWSSLRMREEDADFFTTAQCLSDSRIEGNITGVAVHYNSNHVYFS----EGSRIWVKGAGNLTDHSDLKLLHT----APLEVTALTVDWLYLRIYYASGGRIHYCGLDDCLS-------PVDTNVNLSSDAVNIIADPYNGWLYMLLSTGIYRSPLPDVSSQQQEISHIIKMPSVSNFVVSFPNKRIVYHDRSDQTLNATSLDG-LFPITLYTNVNFEAN---------SIVYEDNFFMLTNGYAVYKQVGQSQVPTFFEFAMDCDIIHSENGGFDNLCYFSTSAQLYPVPRKPKDLQVLFGSDKAYVYWNKPE----SMMGA--------------SPSAWQNWTYAINCTMNG--LVVMSIREVTSTYATVPDLQSSQHYNVTVRACSPGG-CSRSLSYEGTTLHPADEPPYIAAASDGDILKQDLDNIEFMEQIVSLIGDVKDMDWYNSTIYWTNSSGHINWFDLNNRSLSVMTMPSTPVHAEALAFDWLGQYLYWSCNT-NQICRGSTSGQAVEIFLQADQKILSLVIDSLNAAIYWTTETSVEACRLDGEGFQLLDKLSVFSGKEVAGVTLNMIEGNLYWLVQDGSLLNLYRVNISGDRMQKSKAVEFAKWTTSQIFDHQVSYYSERLVWLDEN-KQLRIQELNQNNSVLMSSNNTLTAFSVVQKMLKPLPDGFVSPPVVIPPAVS--KIVLVGNASFFQIHWE-PSSVDYGTVFYCVVSKEVWKNLDPLPN---MFPTRYCHPVNTFTETVINVTRFKPGAELNITITPFSYWGKGKSTETILITPAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSDTDKTLIIAIVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAVGVTLIILILAVVIWQRHHKKKDHGKAKQPSSVQIHPDVELEYVRGLVG---LENGCFAISNTPSRAEIESLPVFPRDCLKLQRLLGSGAFGEVYEGVTVGSQINGVEPERKVAIKTLQKDASDYEKTEFLKEAHLMSQFNHPNILRLLGVCLLNEPHYLILELMEGGDLRSYLRGARPTNNHKE----LLSLSSLLDISLDAATGCAYLERMHFVHRDIAARNCLVSVRTYTDPE-RVVKIGDFGLARDVYKNDYYRKKGEGLLPVRWMSPESLTDGIFNKYSDVWAFGVLLWEILTLGKLPYPTYTNHEVLSYISTGGRLSSPAGCPQRLYNLMMSCWSKQPADRPNFQFLEETMRKLRNYEADKRAN--QTDGADGHVNQAYLGDEEEVCAGVEEDEDLETGLSPVLSNEGLNYLMYRAES----------LNSVQSDSSNGRED------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13368-1", "uniprot_id": "7LESS_DROME", "id": "P13368-1", "name": "Protein sevenless", "aln": "MTMFWQQNVDHQSDEQDKQAKGAAPTKRLNISFNVKIAVNVNTKMTTTHINQQAPGTSSSSSNSQNASPSKIVVRQQSSSFDLRQQLARLGRQLASGQDGHGGISTILIINLLLLILLSICCDVCRSHNYTVHQSPEPVSKDQMRLLRPKLDSDVVEKVAIWHKHAAAAPPSIVEGIAISSRPQSTMAHHPDDRDRDRDPSEEQHGVDERMVLERVTRDCVQRCIVEEDLFLDEFGIQCEKADNGEKCYKTRCTKGCAQWYRALKELESCQEACLSLQFYPYDMPCIGACEMAQRDYWHLQRLAISHLVERTQPQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEELDLEQEDQDASGETGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPATPAYQTPPEGAPISAPVIEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEGNATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVAKGFVQTHSARNEKPAKDLTESVLLVGRRAVMWQSLEPAGENSMIYQSQEELADIAWSKREQQLWLLNVHGELRSLKFESGQMVSPAQQLKLDLGNISSGRWVPRRLSFDWLHHRLYFAMESPERNQSSFQIISTDLLGESAQKVGESFDLPVEQLEVDALNGWIFWRNEESLWRQDLHG-----RMIHRLLRIRQPGWFLVQPQHFIIHLMLPQEGKFLEISYDGGFKHPLPLPPPSNGAGNGPASSHWQSFALLGRSLLLPDSGQLILVEQQG----QAASPSASWPLKNLPDCWAVILLVPESQPLTSAGGKPHSLKALLGAQAAKISWKEPERNPYQ------------------SADAARSWSYELEVLDVAS-QSAFSIRNIRGPIFGLQRLQPDNLYQLRVRAINVDGEPGEWTEPLAARTWPLGPHRLRWASRQGSVIHTNELGEGLEVQQEQLERLPGPMTMVNESVGYYVTGDGLLHCINLVHSQWGCPISEPLQHVGSVTYDWRGGRVYWTDLARNCVVRMDPWSGSRELLP--VFEANFLALDPRQGHLYYATSSQLSRHGSTPDEAVTYYRVNGLEG-SIASFVLDTQQDQLFWLVKGSGALRLYRAPLTAGGDSLQMIQQIKGVFQAVPDSLQLLRPLGALLWLERSGRRARLVRLAAPLDVMELPTPDQASPASALQLLDPQPLPPRDEGVIPMTVLPDSVRLDDGHWDDFHVRWQPSTSGGNHSVSYRLLLEFGQRLQTLDLSTPFARLTQLPQAQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVERLATALQEANVSAVLRWDAPEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEHLQPD---QTYHFQVEARVAATGAAAGAASHALHVAPEVQAVPRVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEGEQRLLWVNEHVELLTHVPGSAPAKLAR--MRAEVLALAVDWIQRIVYWAELDATAPQAAIIYRLDLCNFEGKILQGERVWSTPRGRLLKDLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTDGSELEWATVQPLIRLHAGSLEPGSETLNLVDNQGKLCVYDVARQLCTASALRAQLNLLGEDSIAGQLAQDSGYLYAVKNWSIRAYGRRRQQLEYTVELEPEE-VRLLQAHNYQAYPPKNCLLLPSSGGSLLKATDCEEQRCLLNLPMITASEDCPLPIPGVRYQLNLTLARGPGSEEHDHG----VEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASATPSPPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWAGTPDPLG-SLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRYQCRLLLGYAATPGAPLYHGTAEVYETLGDAPSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDIRRRRRRRRRNSGGSLEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSPEKRGSLVLAIIAPAAIVSSCVLALVLVRKVQKRRLRAKKLLQQSRPSIWSNLSTLQTQQQLMAVRNRAFSTTLS--DADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQ---RVAIKSLRKGAS--EFAELLQEAQLMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAIS----TDLRRTQMASATADTVVSCSRPEFKVRFDGQPLEEHREHNERPEDENLTLREVPLKDKQ----------LYANEGVSRL----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . .:: : .* . . : * ::: * :. : *: . * : . . :: * *:* * ** . : . **.:* *:* * * * :* * :: . . . : * * * . *** *:.*.* *. : : * .* * :::: :*: *:*. *:. : * : :. : : * * : .. :::.:: ..: ::: * : : . :: .:*:: . ::.***: *:*: . . . :: .*. **::: .::* * :::. * :. * : ** . *:. .. :::.:. : . . : : : . * . :*:.:..*:*: * : *. * ...* :.*:* :: . : :: . : **. * : *** . .: * * :..: . . * *.:: : : . : . . . :::::* * :**: : : * . ::. :.:*. . :*::* .:. : :.* .: ...*: :. *:***:.. :.** . : . :: : . : *.*:: : .: .* : *.* * : : *: . *:: *: ..: . * * : . : .. .. :. :: * : * : : . . ::: . ..: : : : . :: ..: * : * :* :: : * .:: :* ** : . *.* :************ :**:*:*:*.:: * *:*:**:***:*:* **: :*:*: *. :*:* **.*** :*** ** :. *:* .*: :.:* :.** *** ***:***:*.*****: : * **********::** *****.**********:**.* **:*.. ****:**:* *******: **.: .* :** ::. ****. * *.: *:.*: ** :* :**.* : :: : . . . : . : :: .. *. : : * . : ", "identical_positions": 250, "similar_positions": 375, "identity": "9.39%" }, { "cls_id": "homologset.agr.FB:FBgn0003371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18265-1", "uniprot_id": "GSK3A_RAT", "id": "P18265-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-----------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASV---------------------------GAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERS-------QEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV---FKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRSL-GTQLPNNRPLPPLFNFSPGELSIQPSLNAILIPPHLR------------------SPSG-----PATLTSS-SQALTETQTGQDWQAPDAT-PTLTN-------------------SS--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49840-1", "uniprot_id": "GSK3A_HUMAN", "id": "P49840-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-----------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASV---------------------------GAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPERS-------QEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV---FKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCL-GTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLR------------------SPAG-----TTTLTPS-SQALTETPTSSDWQSTDAT-PTLTN-------------------SS--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2NL51-1", "uniprot_id": "GSK3A_MOUSE", "id": "Q2NL51-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-----------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASV---------------------------GAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATVGQGPERS-------QEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV---FKSSKTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRRL-GAQLPNDRPLPPLFNFSPGELSIQPSLNAILIPPHLR------------------SPAGPASPLTTSYNPS-SQALTEAQTGQDWQPSDATTATLAS-------------------SS--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV60-1", "uniprot_id": "GSK3B_MOUSE", "id": "Q9WV60-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-----------MSG------------RPRTTSFAE----------------------SCKPVQQ---------------------------PSAFGSMKVSRD-----------------------------KDGSKVTTVVATPGQGPDRP-------QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP-NVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR-----------------IQAAA-----SPPANAT---AASDTNAGDRGQTNNAASASAS-------------------NST--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18266-1", "uniprot_id": "GSK3B_RAT", "id": "P18266-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-----------MSG------------RPRTTSFAE----------------------SCKPVQQ---------------------------PSAFGSMKVSRD-----------------------------KDGSKVTTVVATPGQGPDRP-------QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDMWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP-NVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR-----------------IQAAA-----SPPANAT---AASDTNAGDRGQTNNAASASAS-------------------NST--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49841-1", "uniprot_id": "GSK3B_HUMAN", "id": "P49841-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-----------MSG------------RPRTTSFAE----------------------SCKPVQQ---------------------------PSAFGSMKVSRD-----------------------------KDGSKVTTVVATPGQGPDRP-------QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKV----FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDP-NVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR-----------------IQAAA-----STPTNAT---AASDANTGDRGQTNNAASASAS-------------------NST--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVR7-1", "uniprot_id": "A0A8M3AVR7_DANRE", "id": "A0A8M3AVR7-1", "name": "Glycogen synthase kinase-3 beta", "aln": "-----------MSG------------RPRTTSFAE----------------------SCKPVPQ---------------------------PSAFGSMKVSRD-----------------------------KDGSKVTTVVATPGQGPDRP-------QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGDKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPMVYVKLYMYQLFRSLAYIHSFG-ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVSKQVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELREP-NVKLPNGREKPSLFNFTTQELSSNPTLASILIPAHAR-----------------NQAGA-----STPTNPS---ATSDANSGDRSQTTTAASASAS-------------------NTST-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18431-2", "uniprot_id": "SGG_DROME", "id": "P18431-2", "name": "Protein kinase shaggy", "aln": "-----------MSG------------RPRTSSFAE----------------------GNKQSP----------------------------SLVLGGVKTCS------------------------------RDGSKITTVVATPGQGTDRV-------QEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKV----FRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELSIQPSLVPQLLPKHLQNASGPGGNRPSAGGAASIAASG-----STSVSSTGSGASVEGSAQPQSQGTAAAAGSGSGGATAGTGGASAGGPGSGNNSSSGGASGAPSAVAAGGANAAVAGGAGGGGGAGAATAAATATGAIGATNAGGANVTDS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50873-1", "uniprot_id": "MRK1_YEAST", "id": "P50873-1", "name": "Serine/threonine-protein kinase MRK1", "aln": "MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTIKKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDGKVANKHENISSKLSKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEK-DEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEIFK-----AEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDETKRC------DTDTYVKAQNLRIFDFDVETELGHVP--------------------------------------------LVERPAIEERLKHFVSAPSSSL-----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38615-1", "uniprot_id": "RIM11_YEAST", "id": "P38615-1", "name": "Serine/threonine-protein kinase RIM11/MSD1", "aln": "-------------------------MNIQSNNS-----------------------PNLSNN--------------------------------------------------------------------------IVSKQVYYAHPPPTIDPNDP---VQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYER-DSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFK-----KEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLD------DGKINQITTDLKLLEFDENVELGHLS--------------------------------------------PDELSSVKKKLY-----PKSK------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. . : . * . ::::. :*:*:****** : : :: : *********:*:*****: *: * * * : * *:**. :..**::***:*:*:*:::*: *:: . : . :: * :***::* *:* :***********:** * :*:******* * :****************:*** :*:..:*:**:.**:******:*:*.*:**:*****:**::* *::::* ***** :. **:**. . .: ::: : : *:* * *: .*:. .:*** : : :: ::. : * : : . ", "identical_positions": 136, "similar_positions": 108, "identity": "21.45%" }, { "cls_id": "homologset.agr.FB:FBgn0003380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17659-1", "uniprot_id": "KCNA6_RAT", "id": "P17659-1", "name": "Potassium voltage-gated channel subfamily A member 6", "aln": "--------------------------------------MRSEKSLTLAAPGEVRGPEG---------------------EQQDAGEFQEAEG------------GGGCCSS--------------------------------------------------------------------------------------------------------------------ERLVINISGLRYETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGDEALAAFREDEGCLPEGGEDE-KPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRMSPASRGSHEEEDEDEDSYAFPGSIPSGGLGTGGTSSFSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQPVS----GGSGQNRQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKATDNG----------LGKP---------------DFAEASRERRSS------------------------YLPTPHRAYAEKRMLTEV--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61923-1", "uniprot_id": "KCNA6_MOUSE", "id": "Q61923-1", "name": "Potassium voltage-gated channel subfamily A member 6", "aln": "--------------------------------------MRSEKSLTLAAPGEVRGPEG---------------------EQQDAGEFQEAEG------------GGGCCSS--------------------------------------------------------------------------------------------------------------------ERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGEEALAAFREDEGCLPEGGEDE-KPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRLSPASR-SHEEEDEDEDSYAFPGSIPSGGLGTGGTSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQSVS----GGSGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKATDNG----------LGKP---------------DFAEASRERRPS------------------------YLPTPHRAYAEKRMLTEV--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17658-1", "uniprot_id": "KCNA6_HUMAN", "id": "P17658-1", "name": "Potassium voltage-gated channel subfamily A member 6", "aln": "--------------------------------------MRSEKSLTLAAPGEVRGPEG---------------------EQQDAGDFPEAGG------------GGGCCSS--------------------------------------------------------------------------------------------------------------------ERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDE-KPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNN-GGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPAS----GGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLRATDNG----------LGKP---------------DFPEANRERRPS------------------------YLPTPHRAYAEKRMLTEV--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10499-1", "uniprot_id": "KCNA1_RAT", "id": "P10499-1", "name": "Potassium voltage-gated channel subfamily A member 1", "aln": "----------------------------------------------------MTVMSG---------------------ENADEAS-AAPGH-----------PQDGSYPRQA----------------------------------------------------------------------------------------------------------DHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIK---EEE-RPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKD-----FTGTIHRIDNTTVI-----------------------------YTSN--IFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE------------QEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSS-PNLA-SDSDLSR-RSSST----ISKS-EYMEIEEDMNNSIAHYRQANIRTGN-------------------------CTATDQNCVNKSKLLTDV--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16388-1", "uniprot_id": "KCNA1_MOUSE", "id": "P16388-1", "name": "Potassium voltage-gated channel subfamily A member 1", "aln": "----------------------------------------------------MTVMSG---------------------ENADEAS-TAPGH-----------PQDGSYPRQA----------------------------------------------------------------------------------------------------------DHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIK---EEE-RPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKD-----FTGTIHRIDNTTVI-----------------------------YTSN--IFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE------------QEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSS-PNLA-SDSDLSR-RSSST----ISKS-EYMEIEEDMNNSIAHYRQANIRTGN-------------------------CTTADQNCVNKSKLLTDV--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09470-1", "uniprot_id": "KCNA1_HUMAN", "id": "Q09470-1", "name": "Potassium voltage-gated channel subfamily A member 1", "aln": "----------------------------------------------------MTVMSG---------------------ENVDEAS-AAPGH-----------PQDGSYPRQA----------------------------------------------------------------------------------------------------------DHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIK---EEE-RPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKD-----FTGTVHRIDNTTVI-----------------------------YNSN--IFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE------------QEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSS-PNLA-SDSDLSR-RSSST----MSKS-EYMEIEEDMNNSIAHYRQVNIRTAN-------------------------CTTANQNCVNKSKLLTDV--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEJ3-1", "uniprot_id": "E7FEJ3_DANRE", "id": "E7FEJ3-1", "name": "", "aln": "---------------------------------------------------MTVVVAG---------------------DNMDETSSTLQGQ-----------PQDSQYSP-----------------------------------------------------------------------------------------------------------------ECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIR---EEE-RPLPDNEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDP-------QGRLQVIGNSTFY-----------------------------YKPN--ILTDPFFVVETLCIIWFSFELIVRFFACPSKPAFFKNMMNTIDVVSIIPYFITLGTEMAEDPEGG-------KEAKGGGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEKDSFFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGDEQAQLLTVSN-PNIA-SDTNSSR-RSSSV----VSKS-EYMEIDEDLNNSIDNFREANLRTGN-------------------------CTVANQNCVNKGKRLTDV--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FFE9-1", "uniprot_id": "E7FFE9_DANRE", "id": "E7FFE9-1", "name": "", "aln": "----------------------------------------------------MTVVAG---------------------DNMDETS-AVPGH-----------PQDT-YPPD------------------------------------------------------------------------------------------------------------HDDHECCERVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPANVPLDMFSEEIKFYELGVEAMEKFREDEGFIR---EEE-RPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDP-------EGRIKIIGNTTYY-----------------------------YKPS--ILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQDG--------KEGK--GEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEKESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLNVSN-PNIA-SDSNSSR-RSSST----VSKS-EYMEIDGDINNSIDNFREANLRTGN-------------------------CTIPNQNCVNKSKLLTDV--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63142-1", "uniprot_id": "KCNA2_RAT", "id": "P63142-1", "name": "Potassium voltage-gated channel subfamily A member 2", "aln": "----------------------------------------------------MTVATG---------------------DPVDEAA-ALPGH-----------PQDTYDPEA--------------------------------------------------------------------------------------------------------------DHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIK---EEE-RPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-DMHGGGVTFHTYSNSTIG-----------------------------YQQST-SFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEK-----------PEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIP-SSPDLKKSRSAST----ISKS-DYMEIQEGVNNSNEDFREENLKTAN-------------------------CTLANTNYVNITKMLTDV--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63141-1", "uniprot_id": "KCNA2_MOUSE", "id": "P63141-1", "name": "Potassium voltage-gated channel subfamily A member 2", "aln": "----------------------------------------------------MTVATG---------------------DPVDEAA-ALPGH-----------PQDTYDPEA--------------------------------------------------------------------------------------------------------------DHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIK---EEE-RPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-DMHGGGVTFHTYSNSTIG-----------------------------YQQST-SFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEK-----------PEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIP-SSPDLKKSRSAST----ISKS-DYMEIQEGVNNSNEDFREENLKTAN-------------------------CTLANTNYVNITKMLTDV--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16389-1", "uniprot_id": "KCNA2_HUMAN", "id": "P16389-1", "name": "Potassium voltage-gated channel subfamily A member 2", "aln": "----------------------------------------------------MTVATG---------------------DPADEAA-ALPGH-----------PQDTYDPEA--------------------------------------------------------------------------------------------------------------DHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIK---EEE-RPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-DMHGSGVTFHTYSNSTIG-----------------------------YQQST-SFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEK-----------PEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIP-SSPDLKKSRSAST----ISKS-DYMEIQEGVNNSNEDFREENLKTAN-------------------------CTLANTNYVNITKMLTDV--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15384-1", "uniprot_id": "KCNA3_RAT", "id": "P15384-1", "name": "Potassium voltage-gated channel subfamily A member 3", "aln": "----------------------------------------------------MTVVPG---------------------DHLLEPEAAGGGGG--------DPPQGGCVSGGG---------------------------------------------------------------------------------------------CDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLR---EEE-RPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSG-----------------------------ASSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAER--------------QGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNST----LSKS-EYMVIEEGGM-NHSAFPQTPFKTGNST-------------------ATCTTNNNPNSCVNIKKIFTDV--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16390-1", "uniprot_id": "KCNA3_MOUSE", "id": "P16390-1", "name": "Potassium voltage-gated channel subfamily A member 3", "aln": "----------------------------------------------------MTVVPG---------------------DHLLEPEAAGGGGG--------DPPQGGCGSGGGG------------------------------------------------------------------------------------------GGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLR---EEE-RPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSG-----------------------------APSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAER--------------QGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNST----LSKS-EYMVIEEGGM-NHSAFPQTPFKTGNST-------------------ATCTTNNNPNSCVNIKKIFTDV--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22001-1", "uniprot_id": "KCNA3_HUMAN", "id": "P22001-1", "name": "Potassium voltage-gated channel subfamily A member 3", "aln": "MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPG---------------------DHLLEPEVADGGG---------APPQGGCGGGG----------------------------------------------------------------------------------------------CDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLR---EEE-RPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSG-----------------------------SRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAER--------------QGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNST----LSKS-EYMVIEEGGM-NHSAFPQTPFKTGNST-------------------ATCTTNNNPNSCVNIKKIFTDV--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q783-1", "uniprot_id": "A0A8M9Q783_DANRE", "id": "A0A8M9Q783-1", "name": "", "aln": "MDDHYNLIDSPSASHR---------------GNNADNHGYAETEK-----DIMTVVAC---------------------DNMLEETAA--------------LPSHLS--------------------------------------------------------------------------------------------------LDRYEP---------DHECC-ERVVINISGLRFETQLKTFNQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFIK---EEE-RPLPDHEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDKD-PTTVS-----PIANVTG-------------------------------PFVSSTFTDPFFVIETLCIIWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITLGTELAER--------------QGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSSFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDGEEHAQYLHVGSCQHLN-STEDLKRTQSTSS----LSKS-EYMVIEEG---INSAFKQPNYS-----------------------------NQNNQNCVNIKKIFTDV--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15385-1", "uniprot_id": "KCNA4_RAT", "id": "P15385-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "--MEVAMVSAESSGCNSHMPYGYA-AQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGP---------------HHHHQTRGAYSSHD----------PQGSRGSREEEATRT------------EKKKK---LHHRQSSFPHCSDLMPS-----GSEEKILRELSEEEEDEEEEEEEEEE-GRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVR-YSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVR---EEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAP--------------------------HLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ----------GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQT-QLTQNAVSCPYLPSNLLKKFRSSTS-SSLGDKS-EYLEMEEGVKESLCGKEEKCQGKGDD------------------------SETDKNNCSNAKAVETDV--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61423-1", "uniprot_id": "KCNA4_MOUSE", "id": "Q61423-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "--MEVAMVSAESSGCNSHMPYGYA-AQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGP---------------HHHHQTRGAYSSHD----------PQGSRGSRRRRRQRT------------EKKK----LHHRQSSFPHCSDLMPS-----GSEEKILRELSEEEEDEEEEEEEEEE-GRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVR-YSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVR---EEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAP--------------------------HLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ----------GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQT-QLTQNAVSCPYLPSNLLKKFRSSTS-SSLGDKS-EYLEMEEGVKESLCGKEEKCQGKGDE------------------------SETDKNNCSNAKAVETDV--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22459-1", "uniprot_id": "KCNA4_HUMAN", "id": "P22459-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "--MEVAMVSAESSGCNSHMPYGYA-AQARARERERLAHSRAAAAAAVAAATAAVEGSGGSGGGS---------------HHHHQSRGACTSHD----------PQSSRGSRRRRRQRS------------EKKK----AHYRQSSFPHCSDLMPS-----GSEEKILRELSEEEEDEEEEEEEEEE-GRFYYSEDDHGDECSYTDLLPQDEGGGG-YSSVR-YSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVR---EEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAP--------------------------HLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ----------GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQT-QLTQNAVSCPYLPSNLLKKFRSSTS-SSLGDKS-EYLEMEEGVKESLCAKEEKCQGKGDD------------------------SETDKNNCSNAKAVETDV--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q929-1", "uniprot_id": "F1Q929_DANRE", "id": "F1Q929-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "--MEFAMVGADSGGCNTHLPYGYAQARARERERERERHSRAAAAAAAEAG-AVGEGGGSTGHPH---------------NHPHQSRAASSTNANNSSAGTASRPSSSSSSQQPQQQQQQQHHEPPQQLLRERKKQRGVARWRRNRAALGGDLRQSELALLGSEEDIMIEEEEEAEGEEEEEDRKSKRSSFVYNMDDEEETVSLTDRRPQS-----GYENVYNEYGCCERVVINVSGLKFETQLKTLAQFPDTLLGDPEKRSRYFDPLRNEYFFDRNRPSFDAILYFYQSGGRLKRPVNVPFDIFSEEVKFYELGDEAMLKFREDEGFVK---EEE-KPLPEDEFKRQIWLLFEYPESSSPARGIAVVSVLVIVISIVIFCLETLPEFRDDKEFLIPG--------KNSTQA------------------------------DNGFTPFNDPFFIVETVCIIWFSFEIIVRFFASPSKADFFKNVMNTIDIVSILPYFITLGTDLAQQQ----------GNG----QQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELALLIFFLVIGVILFSSAVYFAEADEPTSQFTSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDNEDQAPAVEQPPPGCPYFP-DFLRKFKGSPSGSSLGDKAAEYMEMEEGVTESLCGGDTQSPSRGNG------------------------TDLGGKNSSHSRTLQTDV--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19024-1", "uniprot_id": "KCNA5_RAT", "id": "P19024-1", "name": "Potassium voltage-gated channel subfamily A member 5", "aln": "--MEISLVPLENGSAMTLRGGGEAGASCVQTPRGECGCPPTSGLNNQSKETLLRGRTTLEDANQ-----------GGRPLPPMAQELPQPRRLSAEDEEGEGDPGLGTVEEDQAPQ--------------------------------------------------------------------------------------------------------DAGSLHHQRVLINISGLRFETQLGTLAQFPNTLLGDPAKRLHYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIK---EEE-KPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPVPPQPPAPAPGINGS----------------VSGALSSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAEFSRNIMNIIDVVAIFPYFITLGTELAEQQPGG-------GG--QNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNHGSHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEQAALKEEQGNQRRE-SGLDTGGQRKVSCSKASFCKTGGSLESSDSIRRGSCPLEKCHLKAKSN----------------------VDLRRSLYALCLDTSRETDL--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61762-1", "uniprot_id": "KCNA5_MOUSE", "id": "Q61762-1", "name": "Potassium voltage-gated channel subfamily A member 5", "aln": "--MEISLVPMENGSAMTLRGGGEAGASCVQSPRGECGCPPTAGLNNQSKETSPRRRATHEDAGQ-----------GGRPLPPMPQELPQPRRPSAEDEEGEGDPGLGTVEEDQAPQ--------------------------------------------------------------------------------------------------------DSGSLHHQRVLINISGLRFETQLGTLAQFPNTLLGDPVKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIK---EEE-KPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPVPPQPPAPAPGANGS----------------GSGVLSSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAEFSRNIMNIIDIVAIFPYFITLGTELAEQQPGG-------GG--QNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGSHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEQAALKEEQGIQRRE-SGLDTGGQRKVSCSKASFCKTGGPLESTDSIRRGSCPLEKCHLKAKSN----------------------VDLRRSLYALCLDTSRETDL--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22460-1", "uniprot_id": "KCNA5_HUMAN", "id": "P22460-1", "name": "Potassium voltage-gated channel subfamily A member 5", "aln": "--MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDADSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALG----------------------------------------------------------------------------------------------------------TASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIK---EEE-KPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGS----------------GVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGG-------GGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQG-PGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSN----------------------VDLRRSLYALCLDTSRETDL--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRW4-1", "uniprot_id": "D3ZRW4_RAT", "id": "D3ZRW4-1", "name": "Potassium voltage-gated channel subfamily A member 10", "aln": "--MDVCSWREMEVALVNFDNSDEIHE----EPGYATDFDPTSSKGRPGSSPFSNWKVLISDNIS-----------HETAFSKIPGEYVDP-------------PGSEPVVLNEGN----------------------------------------------------------------------------------------------------------------QRVIINIAGLRFETQLRTLNQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDVFADEISFYELGSEAMDQFREDEGFIK---DPE-TLLPTNDFHRQFWLLFEYPESSSAARGVAVVSVLVVVISITIFCLETLPEFREDRELK---------VVRDPTIN--------------------------TNKTGLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKPDFFKNIMNIIDIISIIPYFATLITELVQETE-------------PSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKPNIPGELDKILNS-MGSRTG-------STESLNKTN-----------SSRSAEKSRK-------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RQA1-1", "uniprot_id": "KCA10_MOUSE", "id": "B2RQA1-1", "name": "Potassium voltage-gated channel subfamily A member 10", "aln": "--MDVCSWKEMEVALVNFDNSDEIHE----EPGYATDFDPTSSKGRPGSSPFSNWRVLISDNTN-----------HETAFSKIPGEYVDP-------------PGPEPVVLNEGN----------------------------------------------------------------------------------------------------------------QRVIINIAGLRFETQLRTLNQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDVFADEISFYELGSEAMDQFREDEGFIK---DPE-TLLPTNDFHRQFWLLFEYPESSSAARGVAVVSVLVVVISITIFCLETLPEFREDRELK---------VVRDPSIN--------------------------TNKTGLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFKNIMNIIDIISIIPYFATLITELVQETE-------------PSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKPNIPGELDKILNS-MGSRMG-------STESLNKTN-----------GSCSAEKSRK-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16322-1", "uniprot_id": "KCA10_HUMAN", "id": "Q16322-1", "name": "Potassium voltage-gated channel subfamily A member 10", "aln": "--MDVCGWKEMEVALVNFDNSDEIQE----EPGYATDFDSTSPKGRPGGSSFSNGKILISESTN-----------HETAFSKLPGDYADP-------------PGPEPVVLNEGN----------------------------------------------------------------------------------------------------------------QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIK---DPE-TLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELK---------VVRDPNLN--------------------------MSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETE-------------PSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNS-VGSRMG-------STDSLNKTN-----------GGCSTEKSRK-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A810-1", "uniprot_id": "D4A810_RAT", "id": "D4A810-1", "name": "Potassium voltage-gated channel subfamily A member 7", "aln": "-----MLFLRADTGHPAGVAAASGPHVRSPVAR-------AVRAMEPR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------CPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPVRRSRFYDGARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVSFYGLGAAALARLREDEGCAV---PPE-RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDDPGLAPVAAATGSFLARLNGS-----------------------SPMPGAPSRQPFNDPFFVVETLCICWFSFELLVRLAACPSKAVFFKNVMNLIDFVAILPYFVALGTELAR--------------QRGVGQPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRADTHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMYSHVDTQPCGTLEG------------------------------KANGGLVDSEVP----------------------------ELLPPLWAPSGKHMVTEV--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q17ST2-1", "uniprot_id": "KCNA7_MOUSE", "id": "Q17ST2-1", "name": "Potassium voltage-gated channel subfamily A member 7", "aln": "-----MLFLPADTGHPTGVAAASGPHVRSPVAR-------AVRAMEPR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------CPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPVRRSRFYDGARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVSFYGLGAAALARLREDEGCAV---PPE-RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDDPGLAPVAAATGPFLARLNGS-----------------------SPMPGAPPRQPFNDPFFVVETLCICWFSFELLVRLVACPSKAVFFKNVMNLIDFVAILPYFVALGTELAR--------------QRGVGQPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDTHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMYSHVDTQPCGTLEG------------------------------KANGGLVDSEVP----------------------------ELLPPLWPPAGKHMVTEV--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RP8-1", "uniprot_id": "KCNA7_HUMAN", "id": "Q96RP8-1", "name": "Potassium voltage-gated channel subfamily A member 7", "aln": "--------------------------------------------MEPR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------CPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPV---PPE-RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLA-AAAAAGPFPAPLNGS-----------------------SQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELAR--------------QRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQPCGPLEG------------------------------KANGGLVDGEVP----------------------------ELPPPLWAPPGKHLVTEV--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08510-1", "uniprot_id": "KCNAS_DROME", "id": "P08510-1", "name": "Potassium voltage-gated channel protein Shaker", "aln": "MAAVAGLYGLGEDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLP---------------KLSSQDEEGGAGHG----------FGGGPQHFEP----------------------------------------------------------------------------------------------------------IPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIK---EEE-RPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYK-------------VFNTTTNGT-----------------------KIEEDEVP--DITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSSL-----SESSSDMMDLDDGVESTPGLTETHPGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALAVSIETDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :*::**::**: *: **:****: :* :::* *.****** *****.:**:*****:::**.:*.:*:* :*: ** ** *: :***** * ** ::.**:**.**** .** :*::**:*:::** ******* :: : ****::*: *: **:**: :* ..*.: * ::** **.::*:*** :* * :.. : *:****:***********************:**:******.******.***:**********. : * ***:.******:********* * *****:**********:**********.*******: :: ", "identical_positions": 206, "similar_positions": 87, "identity": "24.73%" }, { "cls_id": "homologset.agr.FB:FBgn0003386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25122-1", "uniprot_id": "KCNC1_RAT", "id": "P25122-1", "name": "Voltage-gated potassium channel KCNC1", "aln": "----------------------------------------------------------------------------------MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPD--------AHSHFD----------------------YDPRAD---------------------EFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSAD--------DADADGPGDSGDG--EDELEMTKRLALSDSP--DGRPGG----------FWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIEN---VRNGTQVRYYREAETEAFLT--YIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQS-------------------------------------------------------DTCPLAQEE-ILEINRA----------DSKLNGEVAKAALANEDCPHIDQALT----PDEGLPFTRSGTRERYG---PCFLLSTGEYACPPGGGMRK---DLCKESPVIAKYMP------------------TEAVRVT------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15388-1", "uniprot_id": "KCNC1_MOUSE", "id": "P15388-1", "name": "Voltage-gated potassium channel KCNC1", "aln": "----------------------------------------------------------------------------------MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPD--------AHSHFD----------------------YDPRAD---------------------EFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSAD--------DADADGPGDSGDG--EDELEMTKRLALSDSP--DGRPGG----------FWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIEN---VRNGTQVRYYREAETEAFLT--YIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQS-------------------------------------------------------DTCPLAQEE-ILEINRA----------GRK---------------------------PLRGMSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48547-1", "uniprot_id": "KCNC1_HUMAN", "id": "P48547-1", "name": "Voltage-gated potassium channel KCNC1", "aln": "----------------------------------------------------------------------------------MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPD--------AHSHFD----------------------YDPRAD---------------------EFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSAD--------DADADGPGDSGDG--EDELEMTKRLALSDSP--DGRPGG----------FWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIEN---VRNGTQVRYYREAETEAFLT--YIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQS-------------------------------------------------------DTCPLAQEE-ILEINRA----------GRK---------------------------PLRGMSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4T7-1", "uniprot_id": "F1Q4T7_DANRE", "id": "F1Q4T7-1", "name": "", "aln": "----------------------------------------------------------------------------------MGQGDDKDRIVINVGGIKHQTYRSTLRTLPGTRLSWLAEPD--------APNNFD----------------------YDANIG---------------------EFFFDRHPSVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFTGGALDLGHD--------DPEPEGVVEAAEG--DEGVEMTRRLAQGDSP--DNRSG-----------RWSRWQKKAWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTETYM---EGNETVERIFPETETMVQLT--YIEGVCVVWFTFEFIIRVTTCPDKLKFLRNTLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFILLIIFLALGVLIFATMIYYAERIGRNPNDPDASSDTHFKNIPIGFWWAVVTMTTLGYGDMYPQTTSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIRRPPLLGSPNYCRSAVNSPRPSTHS-------------------------------------------------------DTCPLAQEE-VSEIRYP----------DFKVNGEPSKAALANEDCPHIDQAVS----PEEVFSPVD---RER-----PCFLLTGGERANHTGGRVRKGYEKPWSHSSMSGGVAS------------------VSALPCSPPCLMQQVHSPIPSIL--------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q14003-1", "uniprot_id": "KCNC3_HUMAN", "id": "Q14003-1", "name": "Voltage-gated potassium channel KCNC3", "aln": "MLSSVCVSSFRGRQGASKQ--QPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPE--------AAARFD----------------------YDPGAD---------------------EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAG--GGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLT--YVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEE-VIEINRA----------DPRPNGDPAAAALAHEDCPAIDQPAM----SPEDKSPITPGSRGRYSRDRACFLLTDYAPSP--DGSIRKATG-APPLPPQD------------------------WRKPGPPSFLPDLNANAAAWISP-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01956-1", "uniprot_id": "KCNC3_RAT", "id": "Q01956-1", "name": "Voltage-gated potassium channel KCNC3", "aln": "MLSSVCVWSFSGRQGTRKQHSQPAPTPQPPESSPPPLLPPPQQQCAQPGTAASPAGAPLSCGPGGRRAEPCSGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPE--------AAARFD----------------------YDPGTD---------------------EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSGNAN-ANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAG--GGAGGPAGGPGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLT--YVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPPGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEE-VIETNRAGNDLGVLEEGDPRPNGDPAAAALAHEDCPAIDQPAM----SPEDKSPITPGSRGRYSRDRACFLVTDYAPSP--DGSIRKATG-APPLPPHAGVSQAPPASCPTSTPTQQPGYPPSGRAPSPPQATPEAPAIFDVWLPPFHRSHQPPGKHQRGGRHPGVSPSPQQRACVGEPPSASHPQSLTLCISVPSSCHRLRPRETLGFPLSLPPRLATGNGGRECPRDPGLPFPSRHSSPAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63959-1", "uniprot_id": "KCNC3_MOUSE", "id": "Q63959-1", "name": "Voltage-gated potassium channel KCNC3", "aln": "MLSSVCVWSFRGRQGTGKQQPQPVPTPQPPESSPPPLPPPQQQQCSQPGTAASPAGAPLSCGPGGRRAEPCPGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPE--------AAARFD----------------------YDPGTD---------------------EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSANAN-ANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAG--GGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLT--YVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVNVAGAYPPGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEE-VIETNRA----------DPRPNGDPAAAALAHEDCPAIDQPAM----SPEDKSPITPGSRGRYSRDRACFLVTDYAPSP--DGSIRKGYEKSRSLSSIVGLSG--------------------VSLRLAPLATPPGSPRATRRAPPTLPSIL-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PG37-1", "uniprot_id": "A0A8M9PG37_DANRE", "id": "A0A8M9PG37-1", "name": "", "aln": "MLSSVCVSSFKGRKGGNKS----------------------SNKACYSADMTCPS--------------------------------ESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPD--------AFSNFD----------------------YDPKSD---------------------EFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEP-------------EVPDDDPALAGDG-------DLKRLCLQEDG--RKAG------------WWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVT---EGNVTREEIVYEVVTDSWLT--YVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILG-----------------------------NVLGGVLGSSGLTG---------DCPLAQEE-IIEINRD-----------SKQNGDAASAALANEDCPTIDQ-VL----SPDERSPVG-RTQERYQQDRACFLLNTREFRPT-DGNVRKGCVISRVCMLASSYILS--------------LFYCLPRPPPPPRSARECVCVCVCCVCCDVTSLIVFSMCFPSLYR--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63734-1", "uniprot_id": "KCNC4_RAT", "id": "Q63734-1", "name": "Voltage-gated potassium channel KCNC4", "aln": "MISSVCVSSYRGRKSGNKP----------------------PSKTCLKEEM--------------------------------AKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPD--------GGGRPE----------------------SDGGGAGSSGSSGGGGG---------CEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGG----------GAGPGDEAGDDER-----ELALQRLGPHEGG--SGPGAGSG--------GCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHR---VGNITSVRFRREVETEPILT--YIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSEETSPRDSTYS-------------------------------------------------------DTSPPAREEGMVERKRA----------DSKQNGD-ANAVLSDEEGAGLTQPLASAPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACA-DGSVQK-------------------------------------EGSVEPKACVPVSHTCAL-----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1C0-1", "uniprot_id": "KCNC4_MOUSE", "id": "Q8R1C0-1", "name": "Voltage-gated potassium channel KCNC4", "aln": "MISSVCVSSYRGRKSGNKP----------------------PSKTCLKEEM--------------------------------AKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPD--------GGGRPE----------------------SDGGGAGSSGSSGGGGGG------GGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGG----------GAGPGDEAGDDER-----ELALQRLGPHEGG--SGPGAGSG--------GCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHR---VGNITSVRFRREVETEPILT--YIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSEETSPRDSTYS-------------------------------------------------------DTSPPAREEGVVERKRA----------DSKQNGD-ANAVLSDEEGAGLTQPLALAPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACA-DGSVRK-------------------------------------EGNVEPKACVPVSHTCAL-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03721-1", "uniprot_id": "KCNC4_HUMAN", "id": "Q03721-1", "name": "Voltage-gated potassium channel KCNC4", "aln": "MISSVCVSSYRGRKSGNKP----------------------PSKTCLKEEM--------------------------------AKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPD--------GGGRPE----------------------TDGGGVGSSGSSG-GGG---------CEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGS----------GAGPSDEAGDDER-----ELALQRLGPHEGG--AGHGAGSG--------GCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR---VGNITSVHFRREVETEPILT--YIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCS-------------------------------------------------------DTSPPAREEGMIERKRA----------DSKQNGD-ANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA-DGSVRKGTFVLRDL----------------------------PLQHSPEAACPPTAGTLFLPH---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22462-1", "uniprot_id": "KCNC2_RAT", "id": "P22462-1", "name": "Voltage-gated potassium channel KCNC2", "aln": "----------------------------------------------------------------------------------MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSGCFEGGAGNCSSHGGNG----SDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGG----------DPGDDEDLG------------GKRLGIEDAAGLGGPDGKSG--------RWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVI-----NGTSAVLQYEIETDPALT--YVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQS--------------------------------------------------------DTCLGKENRLLEHNRS---------------------VLSGDDSTGSEPPLS----PPERLPIRRSSTRDKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGN--------------------ALRLSPVTSPYNSPCPLRRSRSPIPSIL-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14B80-1", "uniprot_id": "KCNC2_MOUSE", "id": "Q14B80-1", "name": "Voltage-gated potassium channel KCNC2", "aln": "----------------------------------------------------------------------------------MGKIESNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSGCFEGGAGNCSSHGGNGGNGGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGG----------DPGDDEDLA------------AKRLGIEDAAGLGGPDGKSG--------RWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVI-----NGTSPVLQYEIETDPALT--YVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQS--------------------------------------------------------DTCLGKENRLLEHNRS---------------------VLSGDDSTGSEPPLS----PPERLPIRRSSTRDKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGN--------------------ALRLSPVTSPYNSPCPLRRSRSPIPSIL-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PR1-1", "uniprot_id": "KCNC2_HUMAN", "id": "Q96PR1-1", "name": "Voltage-gated potassium channel KCNC2", "aln": "----------------------------------------------------------------------------------MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGGRA----SDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGG----------DPGDDEDLA------------AKRLGIEDAAGLGGPDGKSG--------RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVI-----NGTSVVLQYEIETDPALT--YVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQASSPTFCKTELNMACNSTQS--------------------------------------------------------DTCLGKDNRLLEHNRS---------------------VLSGDDSTGSEPPLS----PPERLPIRRSSTRDKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGN--------------------ALRLSPVTSPYNSPCPLRRSRSPIPSIL-------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17972-1", "uniprot_id": "KCNAW_DROME", "id": "P17972-1", "name": "Potassium voltage-gated channel protein Shaw", "aln": "--------------------------------------------------------------------------------MNLINMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALAN----------------------------------YDPILN---------------------EYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTE----------KPSEEELAR--------------KFGFEEDYYKGTIS------------WWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVK---TANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLEN--ADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNP-------HNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLP-VEQPRQPRLPGAPGGVSGCGTPG-----------------------------------------------------------------------S----------------------------------------GPHSGPMGSGGTGPRRMNNKTKDLVS--------------------------------------------------------PKSDMAFSFD--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PUH5-1", "uniprot_id": "A0A8M1PUH5_DANRE", "id": "A0A8M1PUH5-1", "name": "", "aln": "-MSSLGVCS------------------------------------------------------------------------LEASEGSSEKIVLNVGGVKHETLRTTLMSLPGSRLAELVNTE------------------------------------KSPS-----------------------ELFFDRHPEVFAHVLQYYRSGKLHCPSNLCGLLLEEEFTFWGISSADVEPCCWETFQQNKETLKALAGIKPSVMKKEE---------ESGQKQQSS----------------------------------------SSRGWQRKIWALFDKPYSSVCARIIAIISLFFILLSIIAFSLWTLPSINSHQFLNAWAS-----NSTDDFSRTRPPEAQALD--AVEIVCSIWFVFEFAIRAGSCPSKLWFFINVMNIVDLLALFPWFFRWSSNNFS----VFALGFLHAMRCIRLLRVFKLMQHVFGVRVLTHTLRASLTSLCIVPLLLSICTLIFGTMFYFAELTHKDS-------YISSSSGLDGFWWALVTLTTVGYGDMLPVTRQGKCVAFLCAMVGVLLIVLPVPIIVNNFLKFSSLVKTKHSMPRMNEKRSVDVGPSYST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::::* ** :*:* ::** .:*.:**: *... . * ****** **: :*:***:**** * ::** * ***: ***:.. :**.*** .: *:::: ::* : : : *:**:.**** *: :.. *::** :** :*.: * : . . . : :* ** **.:*. * .*.. *. . :**:* :* :.::: . :: .:*. . :*::*:*** :* *:::* :*:*** ..: :: ::* : :**.::.*:** . .. *:***:**:**:***** * * * *. ***:.*** *.:***:**.** : * . :: .:*: ..: .. ", "identical_positions": 125, "similar_positions": 133, "identity": "13.12%" }, { "cls_id": "homologset.agr.FB:FBgn0003390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IN38-1", "uniprot_id": "WIF1_RAT", "id": "Q6IN38-1", "name": "Wnt inhibitory factor 1", "aln": "-MARRRAFPAFVLRLWSILPCLLLL-------------------RADAGQPPEES-------------------------------------------------------------LYLWIDAHQARVLIGFEEDILIVS---EGKMAPFTHDFRKAQQR-MPAIPVNIHSMNFTWQASGQAEYFYEFLSLRSLDKGIMADPTVNVPRLGTVPHKASVVQVGFPCLGKQDGVAAFEVNVIVMNSEGNPILRTPQNAIFFKTCQQ-----------------AECPGGCRNGGFCNERRVCECPDGFYGPHCEKALCIPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSATCFNGGTCFYPGKCICPPGLEGEQCELSKCPQPCRNGGKCIGKSKCKCPKGYQGDLCSKPVCEPGCG--AHGTCHEPNKCQCREGWHGRHCNKRYGASLMHAPRPAGAGLER-HTPSLKKAEGRRDPPESNYIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUA1-1", "uniprot_id": "WIF1_MOUSE", "id": "Q9WUA1-1", "name": "Wnt inhibitory factor 1", "aln": "-MARRRAFPAFALRLWSILPCLLLL-------------------RADAGQPPEES-------------------------------------------------------------LYLWIDAHQARVLIGFEEDILIVS---EGKMAPFTHDFRKAQQR-MPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVNVPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVNVIVMNSEGNTILRTPQNAIFFKTCQQ-----------------AECPGGCRNGGFCNERRVCECPDGFYGPHCEKALCIPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCELSKCPQPCRNGGKCIGKSKCKCPKGYQGDLCSKPVCEPGCG--AHGTCHEPNKCQCREGWHGRHCNKRYGASLMHAPRPAGAGLER-HTPSLKKAEDRRDPPESNYIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5W5-1", "uniprot_id": "WIF1_HUMAN", "id": "Q9Y5W5-1", "name": "Wnt inhibitory factor 1", "aln": "-MARRSAFPAAALWLWSILLCLLAL-------------------RAEAGPPQEES-------------------------------------------------------------LYLWIDAHQARVLIGFEEDILIVS---EGKMAPFTHDFRKAQQR-MPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVNVPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQ-----------------AECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCG--AHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAGAQLRQ-HTPSLKKAEERRDPPESNYIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6F9-1", "uniprot_id": "WIF1_DANRE", "id": "Q9W6F9-1", "name": "Wnt inhibitory factor 1", "aln": "-MAFR--TPAVQLHLKACVLLLLGG-------------------LLEAAYQERGT-------------------------------------------------------------MYMWIDANQARILIGFEEDILIVS---EGKMAPFTHDFRKAQQR-MPAIPVNIHHVNFTWQATDQAEYFYEFQTLRSLDKDIMDDPTVNVPLLGSVPHKASVVQVGFPCRGDQDGVAAFEVTILVMDAGGNIILRTPHNAIFFKTCQR-----------------AKCPGGCRNGGYCNERQVCECQDGFYGVHCEKALCSPRCLNGGLCMSPGVCICPPGYFGSSCERANCSTTCLNGGTCFHPGKCICAVSFEGVRCELSKCRQPCRNGGKCTGRNKCKCSKGYHGDLCSKAVCEPSCG--AHGTCVEPNRCQCREGWHGRHCNKRFRGGVSNSQRVSPSKHKSPSVAAAKEAPETSQPSETNYVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3W5-1", "uniprot_id": "WIF1_DROME", "id": "Q9W3W5-1", "name": "Protein shifted", "aln": "MTHQGIGCLVKWLYLVLIVHTLLCIGQLECRQQHHNRNNNNNNRRADSSSSEEGHGNTSDGLDNFADQDASFVGHGHQPRRGQRKKQQGGGGGGSGGGGGNGGGGGSRHNRNEESGISLWINEQQLKMLTALYFPQGYSERLYAIHNSRVTNDLRDTTLYNFLVIPSEVNYVNFTWKS-GRRKYFYDFDRLQTMDESILKAPTLSIRKSGRIPQEQKNFSIFLPCTGNSSGTASFNVGLKIQTRHNKPLSGTPIRLNFKKECAHRGVYDIDASNPTSLTTLQECSLKCGKNGYCNEHHICKCNVGYTGQYCETAFCFPQCLNGGNCTAPSVCTCPEGYQGTQCEGGICKDKCLNGGKCIQKDKCQCSKGYYGLRCEYSKCVIPCKNEGRCIGNNLCRCPNGLRGDHCEIGRKQRSICKCRNGTCVSHKHCKCHPGFYGRHCNGRKRR---HVHRNDDSKF------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * : ** ::. . : :**: :* ::* .: . : : .*:*:*.: : .** ::: :****:: .: :***:* *:::*:.*: **:.: * :*:: . ..: :** *...*.*:*:* : : .: : ** . * * * : :*. * :.*:***:::*:* *: * :**.*:* *:*:*** * :*..* ** *: * .*: . *. .*:***.*: .** *. . * :** *** **:* *:* *.. *:*.:* :** *. : . :*** . ::*:*: *::***** * : * : ", "identical_positions": 107, "similar_positions": 116, "identity": "22.11%" }, { "cls_id": "homologset.agr.FB:FBgn0003391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P33151-1", "uniprot_id": "CADH5_HUMAN", "id": "P33151-1", "name": "Cadherin-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MQRLMMLLATSGACLGLLAVAAVAAAGANPAQRDT--------------------------HSLLPTHRRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKN--AKYLLKG-----------EYVGKVFRVDAE----------------------------------------------------------------------TGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTH--------------------------------------------------------------------------------------------------------------RLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKE------YFAID-NSGRIITITKSLDREKQARYEIVVEARDAQG------LRGDSGTATVLVTLQDINDNFPFFTQT--------KYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILR--GDYQDAFTIETNPAH------NEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAG-NRAQVIINITDV-DEPPIFQQPFYHFQLKENQK-KPLIGTVLAMDPDA-ARHSIGYSIRRTSDKGQFFRVT-KKGDIYNEKELDREV----YPWYNLTVEAKELDST--------GTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHG----QLVLQISAIDKDITPRNVKFKFILN---TEN-NFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFC--EDMAAQVGVSIQ-------------------------------------AVVAILLCILTIT-VITLLIFLRRRLRKQARAHGKSV---PEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGA------------------KPPRPALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGD------------------------------------------------------------------------------------GPPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDFLN-----------------------DWGPRFKMLAELYGSDPREELLY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M7E5-1", "uniprot_id": "F1M7E5_RAT", "id": "F1M7E5-1", "name": "Cadherin-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MQRLTELATALGTFLGLLAVAAMAGP------------------------------------NMLPVHQRQKRDWIWNQMHIDEEKNESLPHYVGKIKSNVNRQN--AKYVLQG-----------EQAGKIFRVDAD----------------------------------------------------------------------TGDVLAYERLDREKVSEYFLTALIVDKKTNKNLEQPSSFTVKVHDVNDNWPVFTH--------------------------------------------------------------------------------------------------------------QVFNASVPEMSAIGTSVIRVTATDADDPTVAGHATVLYQMVKGNE------YFAID-NSGLIFTKDKNLDRETRAEYKIVVEAQDAQG------LRGESGTATVLIRLEDINDNFPIFTQS--------TYTFSVPEDIRVGKPLGSLSVEDPDEPQNRMTKYSIMQ--GEYRDTFTIETDPDR------NEGIIKPTKPLDYELIQQYTFHIEATDPTIRLGYLSSTAGKNKAKIIINVLDV-DEPPVFQRRFYHFHLPENKK-KPLIGTVVAKDPDK-AQRSIGYSIRKTSDRGQYFRIT-KQGNIYNEKELDRET----HAWYNLTVEANELDSR--------GNPVGKESIVQIYIEVLDENDNAPEFAQPYEPKVCENAAQG----KLVVQISATDKDVVPVNTKFKFALK---NEDSNFTLINNHDNTANITVKYGQFNREHTKFHYLPVLISDNGMPSLTGTGTLTVAVCKCNEQGEFTFC--EEMAAQAGVSIQ-------------------------------------ALVAIFLCILTITAVITLLIFLRRRLRKQAHAHSKSA---LEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRTGSN------------------KPLRSTMDARPAVYTQVQKPPRLAPSLHGGPREMATMIEVKKEEADNDGG------------------------------------------------------------------------------------GPPYDTLHIYGYEGTESIAESLSSLSTNSSDSDIDYDFLN-----------------------DWGPRFKMLAELYGSDPQEELII------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55287-1", "uniprot_id": "CAD11_HUMAN", "id": "P55287-1", "name": "Cadherin-11", "aln": "--------------------------------------------------------------------------------------------------------------MKEN-------------------------YCLQAALVCLGMLCHSHAFAP---ERRGHLRPSFHGHH------------------------EKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSG-----------EGAGTIFVIDDK----------------------------------------------------------------------SGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH--------------------------------------------------------------------------------------------------------------ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGH-----MGGLSGTTKVTITLTDVNDNPPKFPQS--------VYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVD--GDGMESFEITTDYET------QEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREE----TAWLNITVFAAEI------------HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG-------------------------------------ALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEE-----EDVRENIITYDDEGGGEEDTEAFDIATLQNP------------------------DGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPT------------------------------------------------------------------------------------APPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQ-----------------------NWGPRFKKLADLYGSKDTFDDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MAH6-1", "uniprot_id": "F1MAH6_RAT", "id": "F1MAH6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MKEN-------------------------YCLQAALVCLSMLYHSQAFAL---ERRSHLRPSFHGHH------------------------EKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSG-----------EGAGTIFVIDDK----------------------------------------------------------------------SGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH--------------------------------------------------------------------------------------------------------------ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGH-----MGGLSGTTKVTITLTDVNDNPPKFPQS--------VYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVD--GDGMELFEITTDYET------QDGVVKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREE----TAWLNISVFAAEI------------HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDHPKPLSNQPIVTVSADDLDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG-------------------------------------ALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEE-----EDVRENIITYDDEGGGEEDTEAFDIATLQNP------------------------DGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPT------------------------------------------------------------------------------------APPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQ-----------------------NWGPRFKKLADLYGSKDTFDDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55286-1", "uniprot_id": "CADH8_HUMAN", "id": "P55286-1", "name": "Cadherin-8", "aln": "--------------------------------------------------------------------------------------------------------------MPERL--------------------AEMLLDLWTPLIILWITLPPCIYMAPMNQSQVLMSGSPLELN------------------------SLGEEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSG-----------DGAGTIFQINDV----------------------------------------------------------------------TGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLN--------------------------------------------------------------------------------------------------------------GPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP------YFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGH-----SGGLSGTTTLTVTLTDVNDNPPKFAQS--------LYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIID--GDGTALFEITSDAQA------QDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDA-DEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDI-TSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL----SVWHNITIIATEI------------RNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPG----QVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMG-------------------------------------ALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDD-----EDVRENIIRYDDEGGGEEDTEAFDIATLQNP------------------------DGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPT------------------------------------------------------------------------------------APPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLS-----------------------DWGPRFKRLGELYSVGESDKET-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54800-1", "uniprot_id": "CADH8_RAT", "id": "O54800-1", "name": "Cadherin-8", "aln": "--------------------------------------------------------------------------------------------------------------MPERL--------------------AETLLDLWTPLIILWITLPSFVYMAPMNQAHVLTTGSPLELS------------------------RQSEEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSG-----------DGAGTIFQINDI----------------------------------------------------------------------TGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPPSEFIIKVQDINDNAPEFLN--------------------------------------------------------------------------------------------------------------GPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP------YFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGH-----SGGLSGTTTLTVTLTDVNDNPPKFAQS--------LYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIID--GDGTALFEITSDAQA------QDGVIRLRKPLDFETKKSYTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDA-DEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDI-TSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL----SVWHNISIIATEI------------RNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPG----QVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEPYVLPIGLSMG-------------------------------------ALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDD-----EDVRENIIRYDDEGGGEEDTEAFDIATLQNP------------------------DGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPT------------------------------------------------------------------------------------APPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLS-----------------------DWGPRFKRLGELYSVGESDKET-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55289-1", "uniprot_id": "CAD12_HUMAN", "id": "P55289-1", "name": "Cadherin-12", "aln": "--------------------------------------------------------------------------------------------------------------MLTR---------------------------NCLSLLLWVLFDGGLLTPLQPQPQQTLATEPRENVI------------------------HLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSG-----------DGAGTVFTIDET----------------------------------------------------------------------TGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLD--------------------------------------------------------------------------------------------------------------GPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQP------YFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQ-----LGGLAGTTIVNITLTDVNDNPPRFPKS--------IFHLKVPESSPIGSAIGRIRAVDPDFGQNAEIEYNIVP--GDGGNLFDIVTDEDT------QEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDV-DEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDV-GSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES----TAQYNFSIIASKV------------SNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPG----QIIQIVSAADRDLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTG-------------------------------------ALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSK-----EDIRDNVIHYDDEGGGEEDTQAFDIGALRNP------------------------KVIEENKIRRDIKPDSLCLPR-QRPPMEDNTDIRDFIHQRLQENDVDPT------------------------------------------------------------------------------------APPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYLT-----------------------DWGPRFKVLADMFGEEESYNPDKVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M1A2-1", "uniprot_id": "F1M1A2_RAT", "id": "F1M1A2-1", "name": "Cadherin-12", "aln": "--------------------------------------------------------------------------------------------------------------MLTR---------------------------NSLYLLLWILFDGGLLTPLQPQPQQTLATEPKDNVI------------------------HLLGRRSHFQRVKRGWVWNQFFVLEEYMGSEPQYVGKLHSDLDKGEGTVKYTLSG-----------DGAGTVFTIDET----------------------------------------------------------------------TGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLD--------------------------------------------------------------------------------------------------------------GPYVASVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQP------YFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQ-----LGGLAGTTIVNITLTDVNDNPPRFPKS--------IFHLKVPESSPVGSAIGRIRAVDPDFGKNAEIEYNIVP--GDGGNLFDIVTDEDT------QEGIIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDV-DEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDV-GSSAVRYFIDWKSDGDSYFTIDGTEGTIATNELLDREN----TAQYNFSIIASKV------------SNPSLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPG----QIIQIVGAVDRDLSPAGQQFSFRLAPEAVIKPNFTVHDFRNNTAGIETRRNGYSRRQQELYFLPIVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTG-------------------------------------ALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSK-----EDIRDNVIHYDDEGGGEEDTQAFDIGALRNP------------------------KVIEENKIRRDIKPDSFCLPR-QRPQVEDNTDIRDFIHQRLQENDADPA------------------------------------------------------------------------------------APPYDSLATYAYEGNGSVAESLSSIDSLTSEADQDYDYLS-----------------------DWGPRFKVLADMFGEEESYNPDNVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55285-1", "uniprot_id": "CADH6_HUMAN", "id": "P55285-1", "name": "Cadherin-6", "aln": "--------------------------------------------------------------------------------------------------------------MRTY---------------------------RYFLL-LFWVGQPYPTLSTPLSKRTSGFPAKKRALE------------------------LSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSG-----------DGAGDLFIINEN----------------------------------------------------------------------TGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTK--------------------------------------------------------------------------------------------------------------EVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP------YFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTDVNDNPPRFPQS--------TYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITD--GEGLDMFDVITDQET------QEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDV-DEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDA-ARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRET----LLWHNITVIATEI------------NNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKAD----QLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTG-------------------------------------ALVAILLCIVILLVTVVLFAALRRQRKKEPLIISK-----EDIRDNIVSYNDEGGGEEDTQAFDIGTLRNP------------------------EAIEDNKLRRDIVPEALFLPR-RTPTARDNTDVRDFINQRLKENDTDPT------------------------------------------------------------------------------------APPYDSLATYAYEGTGSVADSLSSLESVTTDADQDYDYLS-----------------------DWGPRFKKLADMYGGVDSDKDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55280-1", "uniprot_id": "CADH6_RAT", "id": "P55280-1", "name": "Cadherin-6", "aln": "--------------------------------------------------------------------------------------------------------------MRTY---------------------------RYFLL-LFWVGQPYPTFSNPLSKRTSGFPAKRRALE------------------------LSANSRNELSRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSG-----------DGAGDLFIINEN----------------------------------------------------------------------TGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTK--------------------------------------------------------------------------------------------------------------DVYTATVPEMADVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP------YFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTDVNDNPPRFPQS--------TYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITD--GEGHDMFDVITDQET------QEGIITVKKLLDFEKKRVYTLKVEASNPHIEPRFLYLGPFKDSATVRIVVDDV-DEPPVFSKPAYILQIREDAQINTTIGSVAAQDPDA-ARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRET----LLWHNITVIATEI------------NNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKAD----QLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTG-------------------------------------ALVAILLCIVILLVTVVLFAALRRQRKKEPLIISK-----EDIRDNIVSYNDEGGGEEDTQAFDIGTLRNP------------------------KPWR-QQSRRDMVPEALFLPR-RTPTARDNTDVRDFISQRLRKMNTDPT------------------------------------------------------------------------------------APPYDSLATYAYEGTGSVADSLSSLESVTTDGDQDYGYLS-----------------------DWGPRFKKLADMYGGMDSDKDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULB4-1", "uniprot_id": "CADH9_HUMAN", "id": "Q9ULB4-1", "name": "Cadherin-9", "aln": "--------------------------------------------------------------------------------------------------------------MRTY---------------------------HYIPL-FIWTYMFHTVDTILLQEKPNSYLSSKKIAG------------------------LTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTG-----------DGAGSLFVIDEN----------------------------------------------------------------------TGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK--------------------------------------------------------------------------------------------------------------DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTDVNNNPPRFPQS--------TYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAE--GDGADMFDVITDKDT------QEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES----SPWHNITVTATEI------------NNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPG----QLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTG-------------------------------------ALVAILLCVLILLILVVLFAALKRQRKKEPLIISK-----DDVRDNIVTYNDEGGGEEDTQAFDIGTLRNP------------------------EAREDSKLRRDVMPETIFQIR-RTVPLWENIDVQDFIHRRLKENDADPS------------------------------------------------------------------------------------APPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLS-----------------------DWGPRFKKLADMYGGDDSDRD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZFQ5-1", "uniprot_id": "D3ZFQ5_RAT", "id": "D3ZFQ5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MRTY---------------------------HFLQL-IVWTWIFQMVDNSPLQGKDNIHLR-KRIVN------------------------LKKDDGKMLHRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTG-----------DGAGNLFVIDEN----------------------------------------------------------------------TGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK--------------------------------------------------------------------------------------------------------------DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTDVNNNPPRFPQS--------TYQFNSLESAPLGTHLGRIKANDPDTGENAELEYSISE--GEGSDMFDVITDKDT------QEGIITVKQNLDFEKKMLYTLRVDASNTHPDPRFLHLGPFKDSAMVKISVEDV-DEPPVFSKLSYLMEVDEDVKEGSIIGQVTAYDPDA-MNNIIKYSVDRHTDMDRVFSIHSENGSIFTLKPLDRES----SPWHNITVTATEI------------NNPKQSSQIAVFIRILDINDHAPEFAMYYETFVCENAKSG----QLIQTISVMDKDDPPRGHKFFFEPVPEFPLNPNFTIVDNKDNTAGIITRKDGYSRNKMNTYLLPVLIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCNAEALMLAAGLSTG-------------------------------------ALIAILLCVVILLTLIVLFAALKRQRKKEPLIISK-----DDVRDNIVTYNDEGGGEEDTQAFDIGTLRNP------------------------EAREDSKLRRDVMPETIFQIR-RTVPLWENIDVQDFIHRRLKENDSDPS------------------------------------------------------------------------------------APPYDSLATYAYEGNDSVANSLSSLESLTADCNQDYDYLS-----------------------DWGPRFKKLAEMYGGDDSDRD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6N8-1", "uniprot_id": "CAD10_HUMAN", "id": "Q9Y6N8-1", "name": "Cadherin-10", "aln": "--------------------------------------------------------------------------------------------------------------MTIH---------------------------QFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSR------------------------VPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSG-----------DGAGTLFIIDEK----------------------------------------------------------------------TGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPE--------------------------------------------------------------------------------------------------------------EIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTDVNDNPPRFPQN--------TIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIID--GDGTDMFDIVTEKDT------QEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL----SQWHNLTVIAAEI------------NNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPG----QLIQTISAVDKDDPLGGQKFFFSLA---AVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG-------------------------------------ALIAILLCIIILLVIVVLFAALKRQRKKEPLILSK-----EDIRDNIVSYNDEGGGEEDTQAFDIGTLRNP------------------------AAIEEKKLRRDIIPETLFIPR-RTPTAPDNTDVRDFINERLKEHDLDPT------------------------------------------------------------------------------------APPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLR-----------------------EWGPRFNKLAEMYGGGESDKDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LR98-1", "uniprot_id": "F1LR98_RAT", "id": "F1LR98-1", "name": "Cadherin-10", "aln": "--------------------------------------------------------------------------------------------------------------MSIY---------------------------SFLRLFVLWACLPQFCCPELTFRRTPGLQQMTAESH------------------------VPRGDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSG-----------DGAGTLFIIDEK----------------------------------------------------------------------TGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPE--------------------------------------------------------------------------------------------------------------EIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGIIRTALPNMNRENKEQYQVVIQAKDMGGQ-----MGGLSGTTTVNITLTDVNDNPPRFPQN--------TIHLRVLESSPVGTAVGSVKATDADTGKNAEVDYRIID--GDGTDMFDIITEKDT------QEGIITVKKPLDYENRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDS-TSSPIRFTLDRHTDLDRIFNIHSGNGSLYTSKPLDREL----SQWHNLTVIAAEI------------NNPKETTRVSVFVRILDVNDNAPQFAVFYDTFVCENARPG----QLIQTISAVDKDDPLGGQKFFFSLA---AVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG-------------------------------------ALIAILLCIIILL--VVLFAALKRQRKKEPLILSK-----EDIRDNIVSYNDEGGGEEDTQAFDIGTLRNP------------------------AAIEEKKLRRDIIPETLFIPR-RTPTAPDNTDVRDFINERLKEHDLDPT------------------------------------------------------------------------------------APPYDSLATYAYEGNDSVAESLSSLESGTTEGDQNYDYLR-----------------------EWGPRFNKLAEMYGGGESDKDA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13634-1", "uniprot_id": "CAD18_HUMAN", "id": "Q13634-1", "name": "Cadherin-18", "aln": "--------------------------------------------------------------------------------------------------------------MKIT---------------------------STSCICPVLVCLCFVQRCYG-TAHHSSIKVMRNQTK------------------------HIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTG-----------EGAGTIFIIDDT----------------------------------------------------------------------TGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTD--------------------------------------------------------------------------------------------------------------GPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQ-----VGGLSGSTTVNITLTDVNDNPPRFPQK--------HYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIIN--GDGMGIFSISTDKET------REGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDV-DEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREE----TPWYNITVTASEI------------DNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPG----QVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTG-------------------------------------ALIAILLCVLILLAIVVLFITLRRS-KKEPLIISE-----EDVRENVVTYDDEGGGEEDTEAFDITALRNP------------------------SAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPS------------------------------------------------------------------------------------VPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLG-----------------------DWGPEFKKLAELYGEIESERTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M702-1", "uniprot_id": "F1M702_RAT", "id": "F1M702-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MRIT---------------------------STSCICPVLVCLCFVQRCYG-TAHHSSIKVTRNQTK------------------------HTEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTG-----------EGAGTIFIIDDT----------------------------------------------------------------------TGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTD--------------------------------------------------------------------------------------------------------------GPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQ-----VGGLSGSTTVNITLTDVNDNPPRFPQK--------HYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSITN--GDGIGVFSISTDKDT------REGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDV-DEPPLFSMPSYVMEVYENAKIGTIVGTVLAQDPDS-ANSLVRYFINHSTEEERFFNIDANTGTIKTSKVLDREE----TPWYNITVTASEN------------DNPDLLSHVSVGIRVLDVNDNPPELAREYDIVVCENSKPG----QVIHTITATDKDDFANGPRFNFFLDERLPMNPNFTLKDNEDNTASILTRRRRFSRTMQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTG-------------------------------------ALIAILLCVVILLAIVVLFITLRRS-KKEPLIISE-----EDVRENVVTYDDEGGGEEDTEAFDITALRNP------------------------SAAEEFKYRRDIRPEVKLTPRHQTLSTLESIDVQEFIKQRLAEADLDPS------------------------------------------------------------------------------------VPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLG-----------------------DWGPEFKKLAELYGEIESERTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBT6-1", "uniprot_id": "CAD20_HUMAN", "id": "Q9HBT6-1", "name": "Cadherin-20", "aln": "-------------------------------------------------------------------------------------------------------------MWTSG----------------------------RMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGEL-------------------EALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSG-----------EGAGIVFTIDDT----------------------------------------------------------------------TGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLD--------------------------------------------------------------------------------------------------------------GPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP------YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQ-----LGGLAGTTTVNITLSDVNDNPPRFPQK--------HYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVD--GDGADAFDISTDPNF------QVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREE----FSWHNITVLAMEM------------NNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAG----QLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRG-------------------------------------ALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDE-----ENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREA---------------------QAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLW------------------------------------------------------------------------------------APPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLT-----------------------DWGPRFRKLAELYGASEGPAPLW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5DWV1-1", "uniprot_id": "CAD20_RAT", "id": "Q5DWV1-1", "name": "Cadherin-20", "aln": "-------------------------------------------------------------------------------------------------------------MWTTG----------------------------RMSNAKSWLGLGTSLYFWALMDLATTVLSSTPMPEVEL-------------------DTLFSGKPQSHQRSRRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSG-----------EGAGIVFTIDDT----------------------------------------------------------------------TGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLD--------------------------------------------------------------------------------------------------------------GPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP------YFSVDSKTGIIRTALMNMDREAKEYYEVIIQAKDMGGQ-----LGGLAGTTTVNITLSDVNDNPPRFPQK--------HYQMSVLESAPVSSTVGRVFAKDLDEGINAEMKYTIVD--GDGADAFDINTDPNF------QVGIITVKKPLSFESKKSYTLKVEGSNPHVEMRFLNLGPFQDTTTVHIIVEDV-DEPPVFEPRFYFVEVPEDVTIGTTIQIISAKDPDM-TNNSIRYSIDRGSDPGRFFYVDITTGALMTARPLDREE----FSWHNITVLAMEM------------NNPSQVGSVAATIKVLDVNDNAPEFPRFYEAFICENAKAG----QLIQTVSAVDQDDPHNGQHFYYSLAPEAANNPNFTVRDNQDNTARILTRRSGFRQQEQSVFYLPILIADSGQPVLSSTGTLTIQVCSCSDDGHVMSCSPEAYMLPVSLSRG-------------------------------------ALIAILACVFVLLVLVLLILSMRRHRKQPYIIDDD-----ENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREA---------------------QAGAAPKTRQDMLPEIESLSRYVPQTCAVSSTVHSYVLAKLYEADMDLW------------------------------------------------------------------------------------APPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLT-----------------------DWGPRFRKLAELYGASEGPSPLW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULB5-1", "uniprot_id": "CADH7_HUMAN", "id": "Q9ULB5-1", "name": "Cadherin-7", "aln": "--------------------------------------------------------------------------------------------------------------MKLG----------------------------KVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQ------------------------------SGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSG-----------EGASSIFIIDEN----------------------------------------------------------------------TGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLD--------------------------------------------------------------------------------------------------------------GPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQ-----NGGLSGTTSVTVTLTDVNDNPPRFPRR--------SYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVD--GDGLGIFKISVDKET------QEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDV-DEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIHNITVLAMES------------QNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPG----QVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTG-------------------------------------ALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEE-----RDIRENIVRYDDEGGGEEDTEAFDMAALRN---L---------------------NVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPG------------------------------------------------------------------------------------APPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLS-----------------------DWGPRFKRLADMYGT--GQESLYS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5DWV2-1", "uniprot_id": "CADH7_RAT", "id": "Q5DWV2-1", "name": "Cadherin-7", "aln": "--------------------------------------------------------------------------------------------------------------MKLG----------------------------KVELCRFLQLIALFLCFSGMNQAELPRSRSKPYFQ------------------------------LGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGFIKYILSG-----------EGASSIFIIDEN----------------------------------------------------------------------TGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLD--------------------------------------------------------------------------------------------------------------GPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQ-----NGGLSGTTSVTVTLTDVNDNPPRFPRR--------SYQYNGPESLPVASVVARIKAADADIGVNAEMEYKIVD--GDGLGIFKISPDKDT------QEGIITIQKELDFEAKTSYTLRIEAANRDADPRFLSLGPFSDTTTVKIIVEDV-DEPPVFSSPLYPMEVSEATQVGHIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGIITTAKSLDRET----NPVHNITVLAMES------------QNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPG----QVIQKISAIDKDEPSNGHQFYFSLTTDMANNLNSSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDNGSPSLSSTNTLTIRVCDCDADGIAQTCNAEAYILPAGLSTG-------------------------------------ALIAILACVLTLLVLILLIVTMKRRKKEPLIFDEE-----RDIRENIVRYDDEGGGEEDTEAFDMAALRN---L---------------------NVVRDTKTRRDVTPEIQFLSRPTFKNIPDNVIFREFIWERLKEADVDPG------------------------------------------------------------------------------------APPYDSLQTYAFEGNGSVAESLGSLDSNSSNSDQNYDYLS-----------------------DWGPRFKRLAEMYGN--GQESLYS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJ99-1", "uniprot_id": "CAD22_HUMAN", "id": "Q9UJ99-1", "name": "Cadherin-22", "aln": "--------------------------------------------------------------------------------------------------------------MRPR----------------------PEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPS--A-------------------PGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISG-----------EGAGTIFLIDEL----------------------------------------------------------------------TGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLH--------------------------------------------------------------------------------------------------------------GPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEH------HFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQ-----LGGLSGSTTVTIVVTDVNDNPPRFPQK--------MYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDT------QEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDV-DEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDA-ANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET----AGWHNITVLAMEA------------DNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPG----QLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPG-------------------------------------ALIALLVCVLILVVLVLLILTLRRHHKSHLSSDED-----EDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAG-GGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLS------------------------------------------------------------------------------------VPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLS-----------------------SWGPRFRPLAALYAGHRGDDEAQAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63315-1", "uniprot_id": "CAD22_RAT", "id": "Q63315-1", "name": "Cadherin-22", "aln": "--------------------------------------------------------------------------------------------------------------MRPR----------------------PAG-ALRAGAALSPVLLLLLLLQ----LLGHLWAASTPAPSSLS-------------------PGTQQDNQLGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGTIKYTISG-----------EGAGTIFLIDEL----------------------------------------------------------------------TGDIHATERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLH--------------------------------------------------------------------------------------------------------------GPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEH------HFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQ-----LGGLSGSTTVTIVVTDVNDNPPRFPQK--------MYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLREESGSGGDAFKVTTDSDT------QEAIIVVQKHLDFESQQVHTVVLEALNKFVDPRFADLGTFRDQAIVRVAVTDV-DEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDA-ANRPVRYAIDRDSDLEQIFDIDADTGAIVTGKGLDRET----AGWHNITVLAMEA------------DNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPG----QLIQTISVVDRDEPQGGHRFYFRLVPEEPSNPHFSLLDIEDNTAAVHTQHVGFNRQEQDVFLLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPG-------------------------------------ALIALLVCVLILVVLALLILTLRRHHKSHLSSDVD-----EDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGD-------------PGGGAASPPQAASSSERHSLPRGPSSPEPDFSVFRDFISRKVALADADLS------------------------------------------------------------------------------------VPPYDAFQTYAFEGAGSPAASLSSLHSGSTGSEQDFAFLR-----------------------AWGPRFRPLAALYAGHRGDDEAPAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H159-1", "uniprot_id": "CAD19_HUMAN", "id": "Q9H159-1", "name": "Cadherin-19", "aln": "--------------------------------------------------------------------------------------------------------------MNCY-------------------------------LLLRFMLGIPLLWPCLGATENSQTKKVKQPVR-------------------------------SHLRVKRGWVWNQFFVPEEMNTT-SHHIGQLRSDLDNGNNSFQYKLLG-----------AGAGSTFIIDER----------------------------------------------------------------------TGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLD--------------------------------------------------------------------------------------------------------------EPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQP------YFSVEPTTGVIRISS-KMDRELQDEYWVIIQAKDMIGQ-----PGALSGTTSVLIKLSDVNDNKPIFKES--------LYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEE---DDSQTFDIITNHET------QEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDV-DEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDN-RKSPIRYSITR----SKVFNIN-DNGTITTSNSLDREI----SAWYNLSITATEK------------YNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSG----QVIQTISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTE-------------------------------------VIIAILICIMIIFGFIFLTLGLKQRRKQILFPEKS-----EDFRENIFQYDDEGGGEEDTEAFDIAELRSS------------------------TIMRERKTRKTTSAEIRSLYRQSLQVGPDSAIFRKFILEKLEEANTDPC------------------------------------------------------------------------------------APPFDSLQTYAFEGTGSLAGSLSSLESAVSDQDESYDYLN-----------------------ELGPRFKRLACMFGSAVQSNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0KZW0-1", "uniprot_id": "A0ABK0KZW0_RAT", "id": "A0ABK0KZW0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MNHY-------------------------------FLKYWILMVPLIWPCLKVAETLKIEKAQRAVP-------------------------------SLGRAKRGWVWKQFVVPEEMDT--IQHVGRLRSDLDNGNNSFQYKLLG-----------TGDGS-FSIDEK----------------------------------------------------------------------TGDIFAMQKLDREKQSLYILRAQVIDTTIGKAVEPESEFVIRVSDVNDNEPRFLD--------------------------------------------------------------------------------------------------------------EPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQP------YFSVEPTTGVIRISS-KMDRELQDTYCVIIQAKDMLGQ-----PGALSGTTTISIKLSDINDNKPIFKES--------FYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSIED---DESQIFDIVIDNET------QEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKVQVEDE-DEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDR-RQSPMRYSLIG----SKMFDIN-GNGTIVTTNLLDREV----SAWYNLSVTATETLQIMSLNRPNIAYNVQQISSAHVYVQVLNINDHAPEFSQLYETYVCENAESG----EIIQTISAIDRDESIEDHHFYFNHSVEDTNNSSFILTDNQDNTAVILSNRAGFSLKEETVFYMIILIADNGIPPLTSTNTLTIQVCDCGDSRSTETCTSKELLFIMGFKAE-------------------------------------AIIAIVICVMVIFGFIFLILALKQRRKETLFPEKT-----EDFRENIFCYDDEGGGEEDSEAFDIIELRQS------------------------TVMRERKPRKSRSAEIRSLYRQSLQVGPDSAIFRKFILEKLEEANTDSS------------------------------------------------------------------------------------APPFDSLQTFAYEGTGSSAGSLSSLGSSVTDQEDDFDYLN-----------------------DLGPCFKRLANMFGSAVQPDN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19022-1", "uniprot_id": "CADH2_HUMAN", "id": "P19022-1", "name": "Cadherin-2", "aln": "-----------------MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKFSNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSE--------------------HAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESVKESAEVEEIVF-------------------PRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSD-RDKNLSLRYSVTGPG-------ADQPPTGIFIINPI----------------------------------------------------------------------SGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLH--------------------------------------------------------------------------------------------------------------QVWNGTVPEGSKPGTYVMTVTAIDADDPNALN-GMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNP----TYGLSNTATAVITVTDVNDNPPEFTAM--------TFYGEVPEN-RVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNS------NDGLVTVVKPIDFETNRMFVLTVAAEN-QVPLAKGIQHPPQSTATVSVTVIDV-NENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPD--RYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDN------------GIPPMSGTGTLQIYLLDINDNAP-QVLPQEAETCETPDPN------SINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAG--IYEVPIIITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTG-------------------------------------AIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDTVEP------------------DAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPT------------------------------------------------------------------------------------APPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLN-----------------------DWGPRFKKLADMYGGGDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z1Y3-1", "uniprot_id": "CADH2_RAT", "id": "Q9Z1Y3-1", "name": "Cadherin-2", "aln": "-----------------MCRIAGGPRTLLPLLAALLQASLEASGELALCKTGFPEDVYSAVLPKTVHEGQPLLNVKFSNCNRKRKVQYESSEPADFKVDEDGTVYAVRSFPLSAE--------------------QAKFLIYAQDKETQEKWQVAVNLSLEPSLTEEPMKEPHEIEEIVF-------------------PRQLAKHSGALQRQKRDWVIPPINLPENSRGPFPQELVRIRSD-RDKNLSLRYSVTGPG-------ADQPPTGIFIINPI----------------------------------------------------------------------SGQLSVTKPLDRELIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLH--------------------------------------------------------------------------------------------------------------QVWNGSVPEGSKPGTYVMTVTAIDADDPNALN-GMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNP----TYGLSNTATAVITVTDVNDNPPEFTAM--------TFYGEVPEN-RVDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNS------NDGLVTVVKPIDFETNRMFVLTVAAEN-QVPLAKGIQHPPQSTATVSVTVIDV-NENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPD--RYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDN------------GIPPMSGTGTLQIYLLDINDNAP-QVLPQEAETCETPEPN------SINITALDYDIDPNAGPFAFDLPLSPATIKRNWTITRLNGDFAQLNLKIKFLEAG--IYEVPIVITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTG-------------------------------------TIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDTVEP------------------DAIKPVGIRRLDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPT------------------------------------------------------------------------------------APPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGDQDYDYLN-----------------------DWGPRFKKLADMYGGGDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L546-1", "uniprot_id": "A0ABK0L546_RAT", "id": "A0ABK0L546-1", "name": "", "aln": "MAQTPGGSDPCRRASENCAHSRAPRVGGIGLPGMLPFLPALGPSECGNVYRGLTNSTFGIETGMDLLSGTYIFAVLLACVVFQSG-AQEKNYTVREEMPENVLIGDLLKDLNLS-----------LIPDKS---LTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAG-------------IVLDAR--CFYEVEVAVLP---DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPA-AIDPDIGINGVQNYQLIKSQ-------------------------------------------------------NVFGLDVVETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDG-GFPQRSSTAILQVSVADTNDNRPIFIE--------------------------------------------------------------------------------------------------------------KEIEVSIPENAPIGSSVTQLHATDAD---IGENARIHFYFSNLVSNN-AKRLFHLNTTTGLITVKE-PLDREESPSHKLLVLATDGGST-------P--AKAMVLVNVTDINDNVPSIDIR--YIVNPTNGTVLLSENAPLNTKIALITVTDKDSEHNGRVTCFTDH-----EVPFRLRP-------VFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQ-------SSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGRNAEINYLLG--FDAPPEFNLDRRTGILTAVKKLDREK----QEKYYFTVLAQDN------------GIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPENLPK------HGTVGLITVTDPDYGENSAVTLSVLDVNDQFTID-----PQSGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSTAKVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTDPG---------------------TVIFKVLAIDNDTGMNAELRYSIVG--GNTKGLFMIEQISGNITLKEKCMVSDIGLHRVIVKAKDLGQPDSLFNVVNVNLFVNESVPNTTLIYEMVRKSIDSPA-NQNSETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQSPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVSIEEAKPDDADNERNSVTLDLPIELEDQTMGKYNWGTTP-TTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SKHHIIQELP-----------------------LDNTFVG-CDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEVVRSHTPMKEATTVEIWTHPHP--QRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHD-PGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPES--------TAEITVQPTVEEASDTCTQECLILGHSDSCWMPASLTNPTPSQIKTSAICHSPPRTHSSVRRCSPPVTQTVAICHSPPVTQAIALCHSPPPVQATVLRHSS------------PPAQASAVCYSPTLVQAVVIHRSPPLPQAATLRHTQAQPPMGLQQGWVQGAGADGTHPIDQGV------QGSTRAQFYTMAERLHPD-DDSIKVIPLTTFTSGKQARASRGDSPIMEEHPL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6ZNL5-1", "uniprot_id": "F6ZNL5_MOUSE", "id": "F6ZNL5-1", "name": "", "aln": "---------------------------------------------------------------MDLLSGTYIFAVLLACVVFQSG-AQEKNYTVREEMPENVLIGDLLKDLNLS-----------LIPDKS---LTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAG-------------IVLDAR--CFYEVEVAVLP---DEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPA-AIDPDIGINGVQNYQLIKSQ-------------------------------------------------------NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDG-GFPQRSSTAILQVSVADTNDNHPIFIE--------------------------------------------------------------------------------------------------------------KEIEVSIPENAPIGSSVTQLHATDAD---IGENARIHFYFSNLVSNI-AKRLFHLNTTTGLITVKE-PLDREESPSHKLLVLATDGGST-------P--ARATVLVNVTDINDNVPSIDIR--YIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDH-----EVPFRLRP-------VFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQ-------SSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLG--FDAPPEFNLDQRTGILTAVKKLDREK----QEKYYFTVLAQDN------------GIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPK------HGTVGLITVTDPDYGENSAVTLSILDVNDQFTID-----PQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTNPG---------------------TVVFKVVAIDDDIGMNAEVLYSIVG--GNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESVPNATLIYELVRRSIDAPA-NQNTETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQPPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVTIEEAKPDDGENERNSVTLDLPIELEEQTMGKYNWGTTP-TTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SKHHIIQELP-----------------------LDNTFVG-CDSISKCSSSSSDPYSVSECSYPVTTFKAPVSVHIRPTMKEVVRSHTPMKEATTVEIWTHPHP--QRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHD-AGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDTCTQECLILGHSDSCWMPATLTNPSPSQIKTSAICHSPPRPRLSVRRYSPPVTQTVTICHSPPVTQAIALCHSPPPVQVTVPRHSP------------PPAQASAVSYSPTLVQAVVIHHSPPLPQAATHHRTQAQPPMGLQQGWVQGAGADGLYPIDQGV------QGSTRAQFYTMAERFHPD-DDSIKVIPLTTFTSGQQARSSRGDSPIIEEHPL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZA7-1", "uniprot_id": "PC11X_HUMAN", "id": "Q9BZA7-1", "name": "Protocadherin-11 X-linked", "aln": "---------------------------------------------------------------MDLLSGTYIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLS-----------LIPNKS---LTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAG-------------IPRDEH--CFYEVEVAILP---DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA-AVDPDVGINGVQNYELIKSQ-------------------------------------------------------NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDG-GFPQRSSTAILQVSVTDTNDNHPVFKE--------------------------------------------------------------------------------------------------------------TEIEVSIPENAPVGTSVTQLHATDAD---IGENAKIHFSFSNLVSNI-ARRLFHLNATTGLITIKE-PLDREETPNHKLLVLASDGGLM-------P--ARAMVLVNVTDVNDNVPSIDIR--YIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDH-----EIPFRLRP-------VFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQ-------SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLG--PDAPPEFSLDCRTGMLTVVKKLDREK----EDKYLFTILAKDN------------GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPR------HGTVGLITVTDPDYGDNSAVTLSILDENDDFTID-----SQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPG---------------------TVVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPV-TPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKK-HSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTP-TTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SKHHIIQELP-----------------------LDNTFVA-CDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQP--QRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHD-AGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQ--GADGLCSVDQGV------QGSATSQFYTMSERLHPS-DDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H7M1-1", "uniprot_id": "A0AC58H7M1_DANRE", "id": "A0AC58H7M1-1", "name": "", "aln": "-------------------------------------------------MEQIFEESAAPTLSMDLASEAHVLVVLFTCLFLMCR-AQEKDYTVKEEQPENVRIGNLRKDLNLN-----------LDPDIK---LSPALQFKPVYKTGDVPLVKVEASTGEILTTANRIDREKLCSG-------------VFNEKR--CYYEIEVAVLP---DEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPS-AFDPDIGINGIQHYELVKSV-------------------------------------------------------SEFGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDG-GNPPKSSTAILQVTVSDVNDNRPVFKD--------------------------------------------------------------------------------------------------------------SEVEVNVPENAPMGTSVTHLHATDAD---LGSNAQIHFSFSNQISPS-TKRHFAIDSTTGLITVKQ-PLDREVNPVHKLIVLASDGSST-------P--SRATVIVNVTDINDNVPSIDTR--YIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDH-----DVPFRLKP-------VFNDQFLLETAAPLDYETTREYAIRIVASDSGKPPLNT-------SAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLG--PDAPDGFNIDSRSGILSVVKRLDREK----QEKYSFTVIARDN------------GTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPENLPL------YGTVGLITVTDADAGDNAVVTLSIINGKDNFIID-----PKTGVIKPNITFDREQQSSYTFVVKAVDAGLMQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVPSNTSPG---------------------SVVTRVFAIDNDTGMNAELQYSIIG--GSLRGLFTIDKTTGNITLQEKIVAADQGLHRLVVKVKDLGQPESLHAIALVHLFVNDTVSNATFIQEQLRKSLETPL-ERNIGDNDVTPQTNGYVIVVIAIIAGTMTVILVIFVTALVRCRQTPRHKVVQKSKQSGEWVSPNQDGR----QIKKKKKKKKRSPKSLLLNFVTIEETKSDDPTHEHVNGTLDLPVELEEQTMGKYNWATTP-TTFKPDSPDLAKHYKSASPQPTFQIKPETPVAPKKHHVIQELP-----------------------LDNTFVVGCDSLSKCSSSSSDPYSVSECSCQGG-FKAPGQIHTR-------QNQTPDKAFPVVPTMCP-------------HKQTQRRVTFHLPDGSQESCSDSGLGEPE-PNSAASITQPLPLGFPQDEYYEQTSPNSRTEGDGNSDPES--------TIEVNLQKALAEASETCTQECLILGHSDSCWMPPALTQFQTSNATT--------------------------------------------------------------------------------------------------------LPSFGFQQSWARGIKPDGRHTLGRSVPKDDLDKGSNRPQFYNTLERHCSKKEDPVKVIPLASFSATSSPQMSSSGGAFLHEHQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZK96-1", "uniprot_id": "A0A8I5ZK96_RAT", "id": "A0A8I5ZK96-1", "name": "", "aln": "---------------------------------------------------------------MDLR-DFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNIS-----------HINAATG--TSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG-------------ASYAEENECFFELEVVILP---NDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPS-ATDPDTGFNGVQHYELLNGQ-------------------------------------------------------SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDG-GTPQKSSTAILQVTVSDVNDNRPVFKE--------------------------------------------------------------------------------------------------------------GQVEVHIPENAPVGTSVIQLHATDAD---IGSNAEIRYIFGAQVAPA-TKRLFALNNTTGLITVQR-SLDREETAIHKVTVLASDGSST-------P--ARATVTINVTDVNDNPPNIDLR--YIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIER-----EVPFHLKA-------VYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQ-------TALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLG--PNAS-FFDLDRKTGVLTASRVFNREE----QERFIFTVTARDN------------GTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK------YSTVGVITVTDEDAGENKAVTLSILNDNENFVLD-----PYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPG---------------------SVVAEVFAVDIDTGMNAELKYTIVS--GNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNASYIYDLIRRTMETPL-DRNIGDSGQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENK----QNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELP-----------------------LDNTFVGGCDTLSKRSSTSSDHFSASECSSQGG-FKTKGPLHTR-----QCNSHSKNDLIPVTHQKCPSSTGFHIRENEESHSESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS---------DGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLS---------------------------------------------------------------------------------------------------------TFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFSN-GSHMADIPLANLKSYKQAGGTIESP---KEHQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPK8-1", "uniprot_id": "F8VPK8_MOUSE", "id": "F8VPK8-1", "name": "", "aln": "---------------------------------------------------------------MDLR-DFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNIS-----------HINAATG--TSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG-------------ASYAEENECFFELEVVILP---NDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPS-ATDPDTGFNGVQHYELLNGQ-------------------------------------------------------SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDG-GTPQKSSTAILQVTVSDVNDNRPVFKE--------------------------------------------------------------------------------------------------------------GQVEVHIPENAPVGTSVIQLHATDAD---IGSNAEIRYIFGAQVAPA-TKRLFALNNTTGLITVQR-SLDREETAIHKVTVLASDGSST-------P--ARATVTINVTDVNDNPPNIDLR--YIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIER-----EVPFHLKA-------VYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQ-------TALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLG--PNAS-FFDLDRKTGVLTASRVFNREE----QERFIFTVTARDN------------GTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK------YSTVGVITVTDEDAGENKAVTLSILNDNENFVLD-----PYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPG---------------------SVVAEVFAVDIDTGMNAELKYTIVS--GNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTAGNTSYIYDLIRRTMETPL-DRNIGDSGQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENK----QNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQGIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELP-----------------------LDNTFVGGCDTLSKRSSTSSDHFSASECSSQGG-FKTKGPLHTR-----QCNSYSKNDNIPVTHQKCPGSTSFHIRENEESHSESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS---------DGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLS---------------------------------------------------------------------------------------------------------TFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFNN-GGHMADIPLANLKSYKQAGGTIESP---KEHQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC56-1", "uniprot_id": "PCDH9_HUMAN", "id": "Q9HC56-1", "name": "Protocadherin-9", "aln": "---------------------------------------------------------------MDLR-DFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNIS-----------HINAATG--TSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG-------------ASYAEENECFFELEVVILP---NDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPS-ATDPDTGFNGVQHYELLNGQ-------------------------------------------------------SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDG-GTPQKSSTAILQVTVSDVNDNRPVFKE--------------------------------------------------------------------------------------------------------------GQVEVHIPENAPVGTSVIQLHATDAD---IGSNAEIRYIFGAQVAPA-TKRLFALNNTTGLITVQR-SLDREETAIHKVTVLASDGSST-------P--ARATVTINVTDVNDNPPNIDLR--YIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIER-----EVPFHLKA-------VYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQ-------TALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLG--PNAS-FFDLDRKTGVLTASRVFDREE----QERFIFTVTARDN------------GTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK------YSTVGVITVTDADAGENKAVTLSILNDNDNFVLD-----PYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPG---------------------SVVAEVFAVDVDTGMNAELKYTIVS--GNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPL-DRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENK----QNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELP-----------------------LDNTFVGGCDTLSKRSSTSSDHFSASECSSQGG-FKTKGPLHTR-----QCNSHSKSDNIPVTPQKCPSSTGFHIQENEESHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS---------DGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLS---------------------------------------------------------------------------------------------------------TFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNN-GSHMTDIPLANLKSYKQAGGATESP---KEHQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4ADD1-1", "uniprot_id": "D4ADD1_RAT", "id": "D4ADD1-1", "name": "Protocadherin-20", "aln": "---------------------MRGQGNARSSLVQAVSLRPATWHPCLDMGHLHRPSSRTSHRNLPHVVLLFLFVGPFNCLASYSR-ATELLYSLNEGLPAGVLIGSLAEDLRLLPRASGRQSQQLLHPERTAAEGNPPLSFSLASGGLSGQYVTLDNRSGELHTSAQEIDREALCLDGGGGAAWGGSTSIASSPSSDSCLLLLDVLVLP---QEYFRFVKVKIAIRDINDNAPQFPISEISVWVPENSPVNTRLAIEHPAVDPDVGINGVQTYRLLDYH-------------------------------------------------------GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDG-GSPPLLGSATLTIGISDINDNCPLFID--------------------------------------------------------------------------------------------------------------SQINVTVYGNATVGTPVTTVQAVDRD---LGTNAQITYSYSQKVPQE-SKELFHLDEVTGVVKLSS-KIGGNVLQTHKLTILANGPGCI-------P--AVITALVSIIKVVFRPPEIVPR--YIANEMDGVVYLKELEPVNTPIAFFTIRDPEGKY--KINCYLEG-----EGPFRLAPY-----KPYNNEYLLETTKPMDYELQPFYEIAVVAWNS--EGFHD-------KRIIKVQLLDDNDNAPVFLQPLIELTIEENNAPNAFLTKLYATDADSGEMGRVSYFLG--PDAPSYFSLDSVTGILTVSTQLDREE----KEKYRYTVRAVDC------------GKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPG------YGEIGVISVTDADAGRNGWVALSVMNQSDIFVID-----TGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTTKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPG---------------------SPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINI-EEKEPQISIKPTHR---KVESMSCMPTLVALSVISLASITLVTGMGIYICLRKGKK------------------------------------------------HHREDDNLEVQIPLKG--------------------------------RIDLCMRERKPMDISNI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIZ0-1", "uniprot_id": "PCD20_MOUSE", "id": "Q8BIZ0-1", "name": "Protocadherin-20", "aln": "---------------------MRGRGNARSLLVQAVSLRPATWHPCLDMGHLHRPSSRTSHRNLPHVFLLFLFVGPFNCLASYSR-ATELLYSLNEGLPAGVLIGSLAEDLRLLPRASGRQNQQLLHPERTASEGNPPLSFSLASGGLSGQYVTLNNRSGELHTSAQEIDREALCLDGGGGAAWAGSTSIASSPSSDSCLLLLDVLVLP---QEYFRFVKVKIAIRDINDNAPQFPISEISVWVPENSPVNTRLAIEHPAVDPDVGINGVQTYRLLDYH-------------------------------------------------------GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDG-GSPPLLGSATLTIGISDINDNCPLFID--------------------------------------------------------------------------------------------------------------SQINVTVYGNATVGTPVATVQAVDRD---LGTNAQITYSYSQKVPQE-TKDLFHLDEVTGVIKLSS-KIGGSVLQTHKLTILANGPGCI-------P--AVITALVSIIKVVFRPPEIVPR--YIANEVDGVVYLKELEPVNTPIAFFTIRDPEGKY--KINCFLDG-----EGPFRLAPY-----KPYNNEYLLETTKPMDYEVQSFYEIAVVAWNS--EGFHV-------KRIIKVQLLDDNDNAPVFLQPLIELTIEENNAPNAFLTKLYATDADSGEMGRVSYFLG--PDAPSYFSLDSVTGILTVSTQLDREE----KEKYRYTVRAVDC------------GTPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPG------YGEIGVISVTDADAGRNGWVALSVMNQSDIFVID-----TGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTTKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPG---------------------SPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINI-EEKEPQISIEPTHR---KVESMSCMPTLVALSVISLGSITLVTGMGIYICLRKGKK------------------------------------------------HHREDDNLEVQIPLKG--------------------------------KIDLCMRERKPVDISNI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6Y1-1", "uniprot_id": "PCD20_HUMAN", "id": "Q8N6Y1-1", "name": "Protocadherin-20", "aln": "---------------------MRGRGNARSSQALGVSWCPATWHPRLDMGRLHRPRSSTSYRNLPHLFLFFLFVGPFSCLGSYSR-ATELLYSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPS-DSCLLLLDVLVLP---QEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDYH-------------------------------------------------------GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDG-GSPPLLGSATLTIGISDINDNCPLFTD--------------------------------------------------------------------------------------------------------------SQINVTVYGNATVGTPIAAVQAVDKD---LGTNAQITYSYSQKVPQA-SKDLFHLDENTGVIKLFS-KIGGSVLESHKLTILANGPGCI-------P--AVITALVSIIKVIFRPPEIVPR--YIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKY--KVNCYLDG-----EGPFRLSPY-----KPYNNEYLLETTKPMDYELQQFYEVAVVAWNS--EGFHV-------KRVIKVQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLG--PDAPSYFSLDSVTGILTVSTQLDREE----KEKYRYTVRAVDC------------GKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPG------YGEIGVISVTDADAGRNGWVALSVVNQSDIFVID-----TGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPG---------------------SPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINI-EEKEPQISIEPTHR---KVESVSCMPTLVALSVISLGSITLVTGMGIYICLRKGEK------------------------------------------------HPREDENLEVQIPLKG--------------------------------KIDLHMRERKPMDISNI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60245-1", "uniprot_id": "PCDH7_HUMAN", "id": "O60245-1", "name": "Protocadherin-7", "aln": "--------------------------------------------------------MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIV----------------------TGSGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMI-------------FDENECFLDFEVSVIGPSQS-WVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPT-ATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDG-GDPPRSSQAILRVLITDVNDNSPRFEK--------------------------------------------------------------------------------------------------------------SVYEADLAENSAPGTPILQLRAADLD---VGVNGQIEYVFGAATES--VRRLLRLDETSGWLSVLH-RIDREEVNQLRFTVMARDRGQP-------PKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVG-----DVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSS-------NNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL--DSSVMGIFAIDPDSGDILVNTVLDREQ----TDRYEFKVNAKDK------------GIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQP------NSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIE-----NDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLP-KNISYTLLPPSSNVR---------------------TVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPL-TQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSK-NKNGYEAGKKDHEDFFTPQQHDKSKKPKKD-KKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGR----------YRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLP-----------------------PANTFVGAG-DNISIGSDHCSEYSCQTNN-KYSKQMR--------------------------------------LHPYITVFG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AB03-1", "uniprot_id": "A0A8I6AB03_RAT", "id": "A0A8I6AB03-1", "name": "", "aln": "--------------------------------------------------------MLRMRTTGWARGWCLGCCLLLPLCFSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIV----------------------TGSGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMI-------------FDENECFLDFEVSVIGPSQS-WVDLFEGRVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPT-ATDRDFGRNGIERYELLQEPGGGGGGGEGRRLGPADSAPYPGGGGNSGSGGGSGGSKRRLDAPEGGGGTGPSGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDG-GDPPRSSQAILRVLITDVNDNSPRFEK--------------------------------------------------------------------------------------------------------------SVYEADLAENSAPGTPILQLRATDLD---VGVNGQIEYVFGAATES--VRRLLRLDETSGWLSVLH-RIDREEVNQLRFTVMARDRGQP-------PKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVG-----DVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREFNVVIVAVDSGSPSLSS-------NNSLVVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL--DSSVMGTFAIDPDSGDILVNTVLDREQ----TDRYEFKVNAKDK------------GIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQP------NSPVGMVTVMDADKGRNAEMSLYIEENSNIFSIE-----NDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLP-RNISYTLLPPSSNVR---------------------TVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDSTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATVIDSQIVRSLHTPL-TQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVMMARYCRSK-SKNGYEAGKKDHEDFFTPQQHDKSKKPKKD-KKNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPSMGR----------YRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLP-----------------------PANTFVGAG-DNISIGSDHCSEYSCQTSN-KYSKQVDTV----------------------QTTNPPGHIEESCKINPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVGEAEHMENDS-------------RPLPDVALTGKCTRECDEYGHSDSCWMPVRTSPER---KKSQPKLSTFMP---------------------------------------------------------------------------------------------VDERGSQEKLAN-------GEAAIMGDRNRNLLNKKLTSSYETFSAASFSKNEEANPEDIPLTKTGEYKPSPVN----TLTRREVYL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08174-1", "uniprot_id": "PCDH1_HUMAN", "id": "Q08174-1", "name": "Protocadherin-1", "aln": "-----------------------------MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGFP----------------------DVG--HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQ-------------LPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPL-ASDRDAGPNGVASYELQAGP----------------------------------------------------EAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDG-GSPPRASSALLRVTVLDTNDNAPKFER--------------------------------------------------------------------------------------------------------------PSYEAELSENSPIGHSVIQVKANDSD---QGANAEIEYTFHQAPEV--VRRLLRLDRNTGLITVQG-PVDREDLSTLRFSVLAKDRGTN-------PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG-----DVPFQLRQASET-GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSS-------TNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQ----RESYELKVVAADR------------GSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPA------LSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP-SNTSHKLLTPQTRLG---------------------ETVSQVAAEDFDSGVNAELIYSIAG--GNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP-PRYGTALVHLYVNETLANRTLLETLLGHSLDTPL-DIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRI------------HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLP-----------------------PANTFVGTG-DTTSTGSEQYSDYSYRTNPPKYPSKQV----------------------------------------GQP----FQLSTPQPLPHPYHGAIWTEVWE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5XVV3-1", "uniprot_id": "A0A8I5XVV3_RAT", "id": "A0A8I5XVV3-1", "name": "", "aln": "------------------------------------MRRRKTVLLILEPARMGPLRPSPGPGGQRLLLPPLLLALLLLLAPSASHTTQVV-YKVPEEQPPNTLIGSLAADYGLP----------------------DVG--HLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQ-------------ISGSPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPL-ATDRDAGPNGVASYELQAGP----------------------------------------------------EAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDG-GSPPRASSALLRVTVLDTNDNAPKFER--------------------------------------------------------------------------------------------------------------PTYEAELSENSPIGHSVIQVKANDSD---QGANAEIDYTFHQAPEV--VRRLLRLDRNTGLITVQG-PVDREDLSTLRFSVLAKDRGAN-------PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG-----DVPFQLRQASET-GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSS-------TNSLRVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEVRVKTSLDREQ----RDSYELKVVAADR------------GSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPA------LSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQ-----NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAP-SNTSHRLLTPQTRLG---------------------ETVSQVTAEDIDSGINAELTYSIAG--GNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP-PRYGTALVHLYVNETLANRTLLETLLVHSLDTPL-DIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKAAKGSKSKGKKSKSPKPVKPVEDEDDTGLQKSLKFNLMSDAPGDSPRI------------HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLP-----------------------PANTFVGTG-DTTSTGSEQYSDYSYRTNPPKYPSKQL----------------------------------------PHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDHYERTTPDGSIGEMEHPENDL-------------RPLPDVAMTGTCTRECSEFGHSDTCWMPGQSSPSR-RTKSSALKLSTFVP---------------------------------------------------------------------------------------------YQDRGGQEPAGA------GSPSPPEDRNTKTAPVRLLPSYSAFSHSSHDSCKDSATLEEIPLTQTSDFPPTATPASAQTSAKREIYL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AI27-1", "uniprot_id": "A0A8M3AI27_DANRE", "id": "A0A8M3AI27-1", "name": "", "aln": "--------------------------------------------------------MCQSANAMWSRWSAMLVWILLLLCCSANVVNTIL-YQVTEEQPPNTLIGSLASDQGLP----------------------DTG--HLYKLEVGAPYLRVDGKTGDIYTTENSIDRESLKDCRNL-------------FEGDPCFLEFEVSITDLMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPV-ATDRDSGSNGIADYALTTGP----------------------------------------------------EATNLFSLQVAQDSD-EKLPQLIVLGNLDRELRDSYDLNIKVVDG-GSPPRQSSALLRITITDANDNVPKFER--------------------------------------------------------------------------------------------------------------SHYEGELPENSPVGHSVLQVKANDSD---MGPNGEVTYSLHQPSSP--VMRLLSIDRNTGIIFVKG-SVDREEISILKFYVQAKDNGPQ-------SKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAG-----DVPFQLRSASET-GNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSS-------TNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQ----LDHYQFLVAAADK------------GVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPP------LSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQ-----NGTYTILSTISFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKP-ANSSYKFLDPRTSPE---------------------THVESVEAEDIDIGLNSELDFNIVG--GNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTP-PRQTTALVHIYVNETIGNVSHVEGLVGHSLYTPL-EMDIAGDPDYSRDP-HSNILFAVLGGFSVVILIIVVAMIIRHLVLKENKSGYQAGKKETKDLYAPKPGPKSNKNKK--AKKSKAPKPANPSEEDEGGTLQKGLKFNLMNENVNDSPRI------------HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQAVQDLP-----------------------ATNTFVGTG-DNNSTGSDQYSDYSYKANSSKYSTKQL----------------------------------------PHRRVTFSTANQAQDLQDPSQHSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPENDL-------------RPLPDVAMTGKCTRECTEYGHSDSCWMPGQPSPNRSKSAKSGPKLSTFVP---------------------------------------------------------------------------------------------YQEREGQERLMADSSSKPHGEERSGGGSNKVASIRFLPPYTSAYSTGGDSGKD-CPREEIPLNQTADYVPATTPSSQGS--KREIYL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PVC3-1", "uniprot_id": "A0A8M1PVC3_DANRE", "id": "A0A8M1PVC3-1", "name": "", "aln": "---------------------------------------------------------------MDLPVVLFLLWGLLLDLLTG-AVGGIL-YRVHEEQPPSTLIGSLAADQGLP----------------------DTG--HLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRN---------------KGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPL-ATDKDTERNGVADYTLTAGP----------------------------------------------------EAVALFGLQVAEDRG-EKLPQLIVLGSLDRELKDSYDLTIKAVDG-GNPPRYSSALLRVVIADANDNAPKFEK--------------------------------------------------------------------------------------------------------------SSYEAEVAENSPIGHSVLQVKANDSD---LGPNGEIEYTLHQAIDP--VPKLLRIDRSSGIIYVKG-PLDREEINNLKFYVVARDKGPS-------PKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAG-----DVPFQLRPASDS-SVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSS-------TNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPFDREH----KDRYEFRVTAADK------------GVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPP------LSPVGMVTVQDMDEGENAQVQLSVEPDVGKFVIQ-----NGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKP-SNSSFIRLSPMAAPD---------------------SVVEVVEAEDIDSGSNAELVYSIAG--GNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKP-SRHAIALVHIYVNETIANVSHVEALVGHSLYTPL-DMDIAGDPDYGLAAQRSNIVYGSLAGVAGVVTVIVVVVFIRHRLQRETKSGYQAGKKETKDLYAPKQGPKSGKGRK--GKKGKPPKSPKPLGEDEEVSLQKSLKFNLD--GVNDSPRI------------HLPLTYPPGSPDLGRHYRSNSPLPSIQLQAQSPSASQKHQAVQELP-----------------------AANTFVGTGGDDNSTGSDQYSDYSYKTNQPKYSTKTL----------------------------------------PHRRVTFSTANPMQDQQDSSQQSYYDSGLEESETPSSKSSSGPRIGPLALPEDHYERTTPDGSIGEMEHPETDI-------------RSLPDVAMTGNCSQECSELGHSDACWMPGQPSPVR--KTRNPPKLSTFVP---------------------------------------------------------------------------------------------YQERGSLGRLAN-------GSVRLGGDENRPR----LPPSRSAYSSSEHAPSDHAPLEEVPLSVTSEFPPTSPPSNHAS--KREIYL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24298-1", "uniprot_id": "CADE_DROME", "id": "Q24298-1", "name": "DE-cadherin", "aln": "------------------MSTSVQRMSRSYHCINMSATPQAGHLNPAQQQTHQQHKRKCRDLGRRLIPARLLLGVIVAISLLSPALALHSPPDKNFSGDNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEK----------------------FVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTIS-ASDFDDGNNSLVEYEILRER------------------------------------------------------------DFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHELGTEHQIKIQVEDVNDNIPYYTEVKSGTILENEPPGTPVMQVRAFDMDG--TSANNIVSFELADNRE------YFTIDPNTGNITALT-TFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRISIGDKNDHKPHFQQD-------KYLAERLLEDANTNTEVIEVKAEDEDNASQILYSIESGN----VGDAFKIGLKTGK----------ITVNQKLDYETITEYELKVRAFDGIYDDYTT----------VVIKIEDVNDNPPVFKQD-YSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDNSGCLRLVKTLDRDPPNGHKNWQVLIKANDED-----------GVGTTVSTVKEVTVTLKDINDNAPFLINEMPVYWQENRNPG-----HVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFS----MDGDYLHANVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEAPETDIGRVFVDDLDDWDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLSFVVTEDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSLKDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQRLENELDLQMLMVNIDECLIEKFKCEESCTNELHKSSVPYMIYSNTTSFVGVNAFVQAQCVCEAPLMRRCLNGGSPRYGENDVCDCIDGFTGPHCELVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALELDNGYPVLTVDYGSGAIRIRHQHIKMVADRTYQLDIILQRTSIEMTVDNCRLSTCQTLGAPIGPNEFLNVNAPLQLGGTPVDLEQLGRQLNWTHVPNQKGFFGCIRNLTINEQTYNLGMPSVFRNIDSGCQQSVAVAFSFGIDRNFIIAIIVCLALLLIILLAVVVQKKQKNGWHEKDIDDIRETIINYEDEGGGERDTDYDLNVLRTQPFYEEKLYKDPHALQG----------------------------------------------------------------------NMRDPNDIPDIADFLGDKKENCDRDVGATTVDDVRHYAYEGDGNSDGSLSSLASCTDDGDLNFDYLSNFGPRFRKLADMYGEEPSDTDSNVDDDQGWRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : :*:. : : . : : : . . * * : * : : * * * : : : :: :. : .. . . : * . : : . . * . * : . * : * : : :.:* . . : : : : * :: * * * : . * * * * : ::*: . : : : *: * : . . : * . : : : : : . . . . : . . : ", "identical_positions": 25, "similar_positions": 82, "identity": "1.44%" }, { "cls_id": "homologset.agr.FB:FBgn0003392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08877-1", "uniprot_id": "DYN3_RAT", "id": "Q08877-1", "name": "Dynamin-3", "aln": "MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRHEIEAETDRVTGMNKGISSVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIRDMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAFKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSG-DQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKRLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFA-----------------NAQQRSSQVHKKSTIGNQGTNLPPS-RQIVIRKGWLTVSNIGIMKGGSKGYWFVLTAESLSWYKDD------------------EEKEKKYMLPLDNLKVRDVEKGFMSS--KHVFALFNTEQRNVYKDYRSLELACDSQEDVDSWKASLLRAGVYPD---KSF----TENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESVEQAQRRDEMLRMYQALKEALAIIGDINTVTVSTPAPPPVDDSWLQHSRRSP-----PPSPTTQRRLTLSAPLP-RPASSRGPAPAIP------SPGPHSGAPPVPFRPG-PLPPFPNSS-DSYG-APPQVPSRPTRAPP------SVPSRRPP---PSPTRPTIIRPLESSLLD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ98-1", "uniprot_id": "DYN3_MOUSE", "id": "Q8BZ98-1", "name": "Dynamin-3", "aln": "MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRHEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIRDMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAFKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSG-DQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKRLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFA-----------------NAQQRSSQVHKKSTIGNQ-----------VIRKGWLTVSNIGIMKGGSKGYWFVLTAESLSWYKDD------------------EEKEKKYMLPLDNLKVRDVEKGFMSS--KHVFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPD---KSVGSNKTENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDINTATVSTPAPPPVDDSWLQHSRRSP-----PPSPTTQRRLTISAPLP-RPTSGRGPAPAIP------SPGPHSGAPPVPFRPG-PLPPFPNSS-DSFG-APPQVPSRPTRAPP------SVPSRRPP---PSPTRPTIIRPLESSLLD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ16-1", "uniprot_id": "DYN3_HUMAN", "id": "Q9UQ16-1", "name": "Dynamin-3", "aln": "MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSG-DQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFA-----------------NAQQRSSQVHKKTTVGNQGTNLPPS-RQIVIRKGWLTISNIGIMKGGSKGYWFVLTAESLSWYKDD------------------EEKEKKYMLPLDNLKVRDVEKSFMSS--KHIFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPD---KSV----AENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSP-----PPSPTTQRRPTLSAPLA-RPTSGRGPAPAIP------SPGPHSGAPPVPFRPG-PLPPFPSSS-DSFG-APPQVPSRPTRAPP------SVPSRRPP---PSPTRPTIIRPLESSLLD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39052-1", "uniprot_id": "DYN2_RAT", "id": "P39052-1", "name": "Dynamin-2", "aln": "MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEYAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGRKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPTLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSG-DQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELISTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFA-----------------NAQQRSTQLNKKRAIPNQG-------EILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDE------------------EEKEKKYMLPLDNLKIRDVEKGFMSN--KHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPE---KDQ----AENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAEQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQNTSSH--------SPTPQRRPVSSVHPPGRPPAVRGPTPGPPLIPMPVGATSSFSAPPIPSRPG-PQNVFANN--DPFS-APPQIPSRPARIPPGIPP--GVPSRRAP---AAPSRPTIIRPAEPSLLD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39054-1", "uniprot_id": "DYN2_MOUSE", "id": "P39054-1", "name": "Dynamin-2", "aln": "MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEYAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPTLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSG-DQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELISTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFA-----------------NAQQRSTQLNKKRAIPNQG-------EILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDE------------------EEKEKKYMLPLDNLKIRDVEKGFMSN--KHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPE---KDQ----AENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAEQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQNTSGH--------SPTPQRRPVSSVHPPGRPPAVRGPTPGPPLIPMPVGATSSFSAPPIPSRPG-PQSVFANN--DPFS-APPQIPSRPARIPPGIPP--GVPSRRAP---AAPSRPTIIRPAEPSLLD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50570-1", "uniprot_id": "DYN2_HUMAN", "id": "P50570-1", "name": "Dynamin-2", "aln": "MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSG-DQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFA-----------------NAQQRSTQLNKKRAIPNQG-------EILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDE------------------EEKEKKYMLPLDNLKIRDVEKGFMSN--KHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPE---KDQ----AENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH--------SPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPG-PQSVFANS--DLFP-APPQIPSRPVRIPPGIPP--GVPSRRPP---AAPSRPTIIRPAEPSLLD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TD14-1", "uniprot_id": "A0AB32TD14_DANRE", "id": "A0AB32TD14-1", "name": "dynamin GTPase", "aln": "MGNRGMEELIPLINKLQDAFSSIGQSCNLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLVNNKAEYAEFLHCKGRKFVDFDEVRQEIEAETDRITGSNKGISPIPINLRVYSPNVLNLTLIDLPGMTKVAVGDQPPDIEHQIRDMIMQFITRESCLILAVTPANMDLANSDALKVAKEVDPQGLRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIDGRKDIRAALAAERKFFLSHPSYRHMAERMGTPHLQKALNQQLTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKCIEGSG-DQVDTAELSGGARINRIFHERFPFELVKIVFDEKELRREISHAIKNVHGVRTGLFTPDLAFEAIVKKQIIKLKEPCLKCIDLVIQELINTFRQCTNKLSSYPRLREETERIVTTYVREREGKTKDQVLLLIDTELSYINTNHEDFIGFANLDLRRLDDGTIPGYSNNSAQQRNIVNKKRAIPNQLGGLREGEAEKVIRKGWLTLN-ISIMKGGSKEYWFVLTAESLSWYKDEEINKNVHLTCFFNICKHITEKEKKYMLPLDNLKLRDVEKGFMST--KHIFAIFNTEQRNVYKDLRQIELACDSQEDMDSWKASFLRAGVYPE---KDQ----VESEEAAPADSFSMDPQLERQVETIRNLVDSYIGIVNKTIRDLMPKTIMHLMINSAKDFIHSELLAYLYSSGDQNSLMEESADQAQRRDEMLRMYHAIKEALSIIGDISTSTISTPVPPPVNDSWIPETS-----------PTPQRRPPTSAPPPNRPPAVRGPTPGPP----PLNPTPSFAAPPIPSRPGQPMNAFGNSSQDPFS-APPQIPSRPARIPP------GVPSRRPP---GAPNRPTIIRPAEPSLLD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05193-1", "uniprot_id": "DYN1_HUMAN", "id": "Q05193-1", "name": "Dynamin-1", "aln": "MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFA-----------------NAQQRSNQMNKKKTSGNQD-------EILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDD------------------EEKEKKYMLSVDNLKLRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETE-ENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPA-VPPA--RPGSRGPAPGPP-----PAGSALGGAPPVPSRPG--------ASPDPFG-PPPQVPSRPNRAPP------GVPSRSGQ---ASPSRPESPRPPFDL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21575-1", "uniprot_id": "DYN1_RAT", "id": "P21575-1", "name": "Dynamin-1", "aln": "MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKIAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVDEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDLAFEATVKKQVQKLKEPSIKCVDMVVSELTSTIRKCSEKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFA-----------------NAQQRSNQMNKKKTSGNQD-------EILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDD------------------EEKEKKYMLSVDNLKLRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETE-ENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPA-VPPA--RPGSRGPAPGPP-----PAGSALGGAPPVPSRPG--------ASPDPFG-PPPQVPSRPNRAPP------GVPSRSGQ---ASPSRPESPRPPFDL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39053-1", "uniprot_id": "DYN1_MOUSE", "id": "P39053-1", "name": "Dynamin-1", "aln": "MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKIAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVDEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFA-----------------NAQQRSNQMNKKKTSGNQD-------EILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDD------------------EEKEKKYMLSVDNLKLRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETE-ENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPA-VPPA--RPGSRGPAPGPP-----PAGSALGGAPPVPSRPG--------ASPDPFG-PPPQVPSRPNRAPP------GVPSLGAWRLNSPQGKHENRAGKARL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BCV1-1", "uniprot_id": "A0A8M2BCV1_DANRE", "id": "A0A8M2BCV1-1", "name": "Dynamin-2", "aln": "MGNRGMEDLIPLVNRMQDAFSAIGQNANLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLVLQLINCPTEYAEFLHCKGKKFTDFDEVRQEIEAETDRITGQNKGISPVPINLRVYSPNVLNLTLVDLPGMTKVPVGDQPADIEAQIRDMLMQFVTKENCLLLAVSPANSDLANSDALKIAKEVDPQGMRTIGVITKLDLMDEGTDAREILENKLLPLRRGYIGVVNRSQKDIDGKKDITAAMSAERKFFLTHPSYRHLADRMGTPYLQKALNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKHFRPDDPSRKTKALLQMVQQFAVDFEKCIEGSG-DQVDTVELSGGARINRIFHERFPFELVKMEFDEKELRKEISYAIKNIHGIRTGLFTPDMAFETIVKRQIAKIKEPCQKCVDLVITELVNTVRQCTKKLAQYPMLREEMERIVTQHIRDRESRTKNQVMLLIDIELAYMNTNHEDFIGFA-----------------NAQQRSSQMNKKKAAGNQD-------EIMVIRKGWLTINNIGIMKGGAKEYWFVMTAENLSWYKDD------------------EEKEKKYMLPLDNLKLRDIEKSFMSS--KHVFALFNTEQRNVYKDYRQLELASDTQEEVDSWKASFLRAGVYPERITDKEKQSDTSDESSSDGFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKDFIHAELLANLYSCGDQNTLMEESAEQAQHREEMLRMYHALKEALNIIGDISTSTVSTAMPPPVDDSWLQVQGGPSGRRSPMSSPTPQRRAPP-GPP---RPGGR-TAPGPP-----TIG-----APPVPSRPG--------ASPDPFGAPPPQVPSRPNRAPP------GVPSRPSK---GSPSHSESPQPSFDS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q2T8-1", "uniprot_id": "A0A8M9Q2T8_DANRE", "id": "A0A8M9Q2T8-1", "name": "dynamin GTPase", "aln": "MGNRGMEDLIPLVNRMQDAFSAIGQNANLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLVLQLINCPTEYAEFLHCKGKKFTDFDEVRQEIEAETDRVTGQNKGISPVPINLRVYSPNVLNLTLVDLPGMTKVPVGDQPADIEHQIKDMLMQFVTKENCLLLAVSPANSDLANSDALKIAKEVDPQGLRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIDGKKDINAAMAAERKFFLSHPSYRHLADRMGTPYLQKTLNQQLTNHIRDTLPGLRAKLQSQLLSIEKEVEEYKNFRPDDPSRKTKALLQMVQQFSVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRKEISYAIKNIHGIRTGLFTPDLAFEAIVKKQIQKLNGPCLKCIDMVVSELTSTIRKCSEKLAQYPMLREEMERIVTQHIRDRESRTKNQVLLLIDIELAYMNTNHEDFIGFA-----------------NAQQRSSQI-KKKAAGNQD-------EIMVIRKGWLTINNIGIMKGGAKEYWFVLTAESLSWYKDD------------------EEKEKKYMLQVDNLKFRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACESQEEVDGWKASFLRAGVYPERVVEKEK-NDAGEENGSDGFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLIPKTIMHLMINNTKEYINAELLASLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALNIIGDISTTTISTSLPPPVDDSWLQVQRTGSGGRSPATSPTPQRRAPPPGPPA--RPGSRGSAPGPP-----AAG-----GPPVPSRPG--------ASPDPFGGPPPTVPSRPNRAPP------SVPSRRPP---ASPTRPY------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5RHR9-1", "uniprot_id": "Q5RHR9_DANRE", "id": "Q5RHR9-1", "name": "Dynamin-2", "aln": "MGNRGMEELIPLVNRLQDAFSAIGQNCDLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLISSASEHAEFLHCKGKKFTDFDDVRREIEAETDRVTGTNKGISSIPINLRVFSPNVLNLTLIDLPGITKVPVGDQPADIEYQIRDMIMQFICKENCLILAVTPANMDLANSDALKLAKDVDPQGHRTIGVITKLDLVDKGTDVRDVLENRLLPLRRGYIGVVNRSQKDIEGKKDISAALAAEKRFFKSHPAYRHMADYMGTPYLQRLLNQQLTNHIRDTLPALRSRLQAQLLSLDKEAEEYKGLNPDDPSRKTKALMQLIQHFGLDFEKRIEGSG-DQVDTVQLSGGAKINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPCLKCVDMVIQELINTVQQCTNKLESFPKLREETERIVTTHIRERESQTKDQVLLSLEIQLSYINTNHEDFIGFA-----------------NAQQKTSQLSNKPSAGNQ-----------VIRKGWVIINNISLIKGGSKEYWFVLTAESLSWFKDD------------------EEKEKKYMLPLDNLKVRDIEKSFMSS--KHVFAIFNTEQRNVYKDYRHLELACDTQDDVDSWKASLLRAGVYPE---KTT----ADGDGSSQTESFSMDPQLERQVETIRNLVDSYMSIVYKSIRDLMPKTIMHLVINNVEEFIHSELLAQLYSSGDQYSLMDESPEQALRREEVLRTHAALKEALNIITDISTTTISTPLPPPVDNSWLSSGS-------------LHRRSPKGYSVP-----KKHPAPAAP------SQHVRLEAQPLPVYNN----------KDNTN-----TTSHPKRVPP------SVPRRQPP---AVPTQHTH-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27619-1", "uniprot_id": "DYN_DROME", "id": "P27619-1", "name": "Dynamin", "aln": "-----MDSLITIVNKLQDAFTSLGVHMQLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLILQLINGVTEYGEFLHIKGKKFSSFDEIRKEIEDETDRVTGSNKGISNIPINLRVYSPHVLNLTLIDLPGLTKVAIGDQPVDIEQQIKQMIFQFIRKETCLILAVTPANTDLANSDALKLAKEVDPQGVRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIEGRKDIHQALAAERKFFLSHPSYRHMADRLGTPYLQRVLNQQLTNHIRDTLPGLRDKLQKQMLTLEKEVEEFKHFQPGDASIKTKAMLQMIQQLQSDFERTIEGSGSALVNTNELSGGAKINRIFHERLRFEIVKMACDEKELRREISFAIRNIHGIRVGLFTPDMAFEAIVKRQIALLKEPVIKCVDLVVQELSVVVRMCTAKMSRYPRLREETERIITTHVRQREHSCKEQILLLIDFELAYMNTNHEDFIGFA-----------------NAQNKSENANKTGTRQLGN---------QVIRKGHMVIQNLGIMKGGSRPYWFVLTSESISWYKDE------------------DEKEKKFMLPLDGLKLRDIEQGFMSMSRRVTFALFSPDGRNVYKDYKQLELSCETVEDVESWKASFLRAGVYPE---KQE---TQENGDESASEESSSDPQLERQVETIRNLVDSYMKIVTKTTRDMVPKAIMMLIINNAKDFINGELLAHLYASGDQAQMMEESAESATRREEMLRMYRACKDALQIIGDVSMATVSSPLPPPVKNDWLPSGLDNPR----LSPPSPGGVRGKPGPPAQSSLGGRNPPLPPS---------TGRPAPAIPNRPG-GGAPPLPGGRPGGSLPPPMLPSRVSGAVGGAIVQQSGANRYVPESMRGQVNQAVGQAAINELSNAFSSRFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.**.::*::****:::* *:***********************:***************:***: :*:.**** *.:** .*:::* *** ****:** ***** :******:**:******:****:***.:**** *** **::*::**: :*..*:***:*** *********:**:***** ***********:*:***.*::***:********:**********:*:*** *: **::** :**:***:*: :***:**: **********::** :* :** *:*::::*.: :* :.* *.: ****::*::*:: ***: ***** ::* :*****:********: **:**: :**:**:***.**:*:**:*.******:***: **:*: :. * *.:*:*: ** ..: *: :: :* * ** ***:: ::*:** *:*::* :: : :*:*********** *: :: :. : ***:* : :. :.::***:: ****:*:*.:**:**: *****:** :*.**.**:*:.*** : **:*..: ****** : :**:.:: ::::.****:*******: . . * ******************: *: * **::**:** *:**..: :* **** **:. ** :*:** :.* :*:::** : * *:** ** *:. *:*:. ****.: *: : .. . . .:* . .*: . . . ", "identical_positions": 417, "similar_positions": 222, "identity": "44.08%" }, { "cls_id": "homologset.agr.FB:FBgn0003396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00900-1", "uniprot_id": "ZEP2_RAT", "id": "Q00900-1", "name": "Human immunodeficiency virus type I enhancer-binding protein 2 homolog", "aln": "------MDTGDTALGQKATSRSGETDSVSGRWRQEQSAGLKMSTFSSQEGQRQPQIDPDQIG---NVASAQLFGSGKLASPGEGVHQVTEKQYPPHR-----------------------------------------------------PSPYPCQHSLSFPQHSLPQGMMHSNKPHQSLEGPPWLFSGPLPSVASEDLFPFPMHGHSSGYPRK--------------------------------------------------------------------------------------------------------------------------------------------------------KISSLNPAYSQY--------SQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPIPLDIASRG----------------GYPGSLEESLGGPMKVPILIIPKSGIPLPN-EGSQYLGPDMLPNPSLNAKADDSHTVKQKLALR-----------------------------------------LSEKKGQ---DSEPSLNLLSPHSKGSTDSGYFSRSESAEQ-QISPPNTNAKSYEEIIFGK---YCRLSPRNTLSVTPTGQERTAMGRRGLVEPLPHVNT---RLEVKMFEDPITQLIPSKGEMDPSQVNMLKTTKFNSECRQPQAMAASVRNEGKPYPGSFPGSNPILLEAP---------------------VDSSPLIRSNSMPTS----SATN--LSIPPSLRGSHSFDERMTGSDDVFYPGTVG-----IPPQRMLRRQAAFELPSVQEGHMEFEHP-----------------------------ARVPKILAGSSLKEKKLVPGDRSGYDYDACRKPYKKWEDPETPKQSYRDISCLSTFKHGGEYFMDPSVPLPGVPTMFGTTCENRKRRKEKSVGDEEDTPMICGGMGSAPGSMMSSEYDSKLQ--DGGRSGFTMTGHESLPHGYSDRLDLARPQLPSRSPSLGSEDLPSAGDPDKMTDLG-KKPPGNVISVIQHTNSLSRPNSFERSESTEMAVSTQDKTP-SPSEMGDSEVLEGPVSPEWAPPGDGAESGSRPTPSQ-----------QVPQHSYHGQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPE----KPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHS-SSFSMSFDRDETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMP--CPHPTEVPEIRSKSFDYGNLSHAPVA-------------GASPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGMDPSVKQEQLEQLHAGLRAAWTT----VLPPLPGDDPGKQVVGPCGQLSSGPPLHLAQQQIMHMDSQ--ESLRNPLIQPTSYMTGKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFTPHPQN----------------SYSKPPFQADIHSSYSLEHVAEHTGKKSADYPHAKEQTYPCYSGASGLHSKNLPPKFPSDPGSKSTEAPPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILG--QNSPAIVICKVDENMTQRTLVTNAAMQ----GIGFNIAQVLGQRTGLEKYPLWKVPQTLPLGLESSIPLCLPS----TSDSAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGSSQSRSSSFSSLSPSSSQDHPAASG----PFPPNREILSGSRAP-PRRKFSGPSESRESSDELDIDETSSDMSMSPQSSSLPTGGSQQEDEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITA--EIYTLAAMHRPGTGKLTSSSAWKQ-FAQMKPDAPFLFGNKLERKLGGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSM--TSVDETETEEAENMEDLHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDEDDED-DDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHG-VPSD--------------------------------------SSLGHSSLISYLVTLPSIQVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSP--KRYLIPKGDLSPRRHLSPRRDLSPMRHLSPR---------------------KEAALRREMSQGDASPRRHLSPR----RPLSPGKDITTRRDLSPRRERRYMTTIRAPSPRRALYHNP-PLPMGQYL-------------------------QTEPIVLGPPNLRRGLPQVP-YFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAP--IPMVPVGGIQMVHSLPPAISGLHPPPTLPLPTEGSEEKKGAPGEALTQDPYTLSRRHEKQAPHVLQSSGLPSSPSSPRLLMKQS--------------TSEDSLNSTERE--QEENIQTCTKAIASLRIATEEAALLGADQPTWVQESPQKPLESAHISIRHFSGPEPGQLCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKGSVDEKQVDFQSSKELSLSTEEGNEPSSEKNRLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHF7-1", "uniprot_id": "ZEP2_MOUSE", "id": "Q3UHF7-1", "name": "Transcription factor HIVEP2", "aln": "------MDTGDTALGQKATSRSGETDSVSGRWRQEQSAVLKMSTFSSQEGPRQPQIDPEQIG---NAASAQLFGSGKLASPGEGLHQVTEKQYPPHR-----------------------------------------------------PSPYPCQHSLSFPQHSLSQGMTHSHKPHQSLEGPPWLFPGPLPSVASEDLFPFPMHGHSGGYPRK--------------------------------------------------------------------------------------------------------------------------------------------------------KISNLNPAYSQY--------SQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPVPLDIASRG----------------GYHGSLEESLGGPMKVPILIIPKSGIPLAS-EGSQYLSSEMLPNPSLNAKADDSHTVKQKLALR-----------------------------------------LSEKKGQ---DSEPSLNLLSPHSKGSTDSGYFSRSESAEQ-QISPPNTNAKSYEEIIFGK---YCRLSPRNTLSVTPTGQERTAMGRRGIMEPLPHLNT---RLEVKMFEDPISQLNPSKGEMDPGQINMLKTTKFNSECRQPQAIPSSVRNEGKPYPGNFLGSNPMLLEAP---------------------VDSSPLIRSNSMPTS----SATN--LSVPPSLRGSHSFDERMTGSDDVFYPGTVG-----IPPQRMLRRQAAFELPSVQEGHMESEHP-----------------------------ARVSKGLASPSLKEKKLLPGDRPGYDYDVCRKPYKKWEDSETLKQSY-----LGSFKQGGEYFMDPSVPVQGVPTMFGTTCENRKRRKEKSVGDEEDVPMICGGMGNAPVGMMSSEYDPKLQ--DGGRSGFAMTAHESLAHGHSDRLDPARPQLPSRSPSLGSEDLPLAADPDKMTDLG-KKPPGNVISVIQHTNSLSRPNSFERSESTEMVACPQDKTP-SPAETCDSEVLEAPVSPEWAPPGDGGESGSKPTPSQ-----------QVPQHSYHAQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPE----KPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADLEHSSGESSFESTGTGLSRSPSQESNLSHS-SSFSMSFDREETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMP--CPHPTEVPEIRSKSFDYGNLSHAPVA-------------GTSPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGVDPSVKQEHMEHLHAGLRAAWSS----VLPPLPGDDPGKQ-VGTCGPLSSGPPLHLTQQQIMHMDSQ--ESLRNPLIQPTSYMTSKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQTHFPHPFAPHPQN----------------SYSKPPFQADLHSSYPLEHVAEHTGKKSADYPHAKEQTYPCYSGTSGLHSKNLPLKFPSDPGSKSTETP-TEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILG--QNSPAIVICKVDENMTQRTLVTNAAMQ----GIGLNIAQVLGQHTGLEKYPLWKVPQTLPLGLESSIPLCLPS----TSDNAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGCFQSRSSSFSSLSPSSSQDHPSASG----PFPPNREILPGSRAP-PRRKFSGPSESRESSDELDMDETSSDMSMSPQSSALPTGGGQQEEEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPSFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITA--EIYTLAAMHRPGAGKLTSSSVWKQ-FAQMKPDAPFLFGNKLERKLAGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSM--TSVDDTETEEAENMEELHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDDDDED-DDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHG-VPSD--------------------------------------SSLGHSSLISYLVTLPSIQVTQLMTPSDSCDDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSP--KRYLIPKGDLSPRRHLSPRRDLSPMRHLSPR---------------------KEAALRREMSQGDASPRRHLSPR----RPLSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYPNP-PLSMGQYL-------------------------QTEPIVLGPPNLRRGIPQVP-YFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAP--IPMVPVGGIQMVHSLPPALSGLHPPPTLPLPTEGSEEKKGAPGEAFAKDPYILSRRHEKQAPQVLQSSGLPSSPSSPRLLMKQS--------------TSEDSLNSTERE--QEENIQTCTKAIASLRIATEEAALLGADPPTWVQESPQKPLESAHVSIRHFGGPEPGQPCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKSSVDEKRVDFQSSKELSLSTEEGNEPSPEKNQLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31629-1", "uniprot_id": "ZEP2_HUMAN", "id": "P31629-1", "name": "Transcription factor HIVEP2", "aln": "------MDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQPQIEPEQIG---NTASAQLFGSGKLASPSEVVQQVAEKQYPPHR-----------------------------------------------------PSPYSCQHSLSFPQHSLPQGVMHSTKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHSGGYPRK--------------------------------------------------------------------------------------------------------------------------------------------------------KISSLNPAYSQY--------SQKSIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKMSPGPPIPLDIASRG----------------GYHGSLEESLGGPMKVPILIIPKSGIPLPN-ESSQYIGPDMLPNPSLNTKADDSHTVKQKLALR-----------------------------------------LSEKKGQ---DSEPSLNLLSPHSKGSTDSGYFSRSESAEQ-QISPPNTNAKSYEEIIFGK---YCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNT---RLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQGSNPVLLEAP---------------------VDSSPLIRSNSVPTS----SATN--LTIPPSLRGSHSFDERMTGSDDVFYPGTVG-----IPPQRMLRRQAAFELPSVQEGHVEVEHH-----------------------------GRMLKGISSSSLKEKKLSPGDRVGYDYDVCRKPYKKWEDSETPKQNYRDISCLSSLKHGGEYFMDPVVPLQGVPSMFGTTCENRKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQMQEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPSLVSEESPSAIDSDKMSDLGGRKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAP-SPSETCDSEISEAPVSPEWAPPGDGAESGGKPSPSQ-----------QVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAQSKEPE----KPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHS-SSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMP--CPHPAEVPEVRSKSFDYGNLSHAPVS-------------GAAASTVSPSRERKKCFLVRQASFSGSPEISQGEVGMDQSVKQEQLEHLHAGLRSGWHHGPPAVLPPLQQEDPGKQVAGPCPPLSSGP-LHLAQPQIMHMDSQ--ESLRNPLIQPTSYMTSKHLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAQHPQK----------------SYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYPCYSGASGLHPKNLLPKFPSDQSSKSTETP-SEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILG--QNSPAIVICKVDENMTQRTLVTNAAMQ----GIGFNIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPLCLPS----TSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDG-LQSGSSSFSSLSPSSSQDYPSVSPSSREPFLPSKEMLSGSRAPLPGQKSSGPSESKESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADSTLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITA--EIYTLAAMHRPGTGKLTSSSAWKQ-FTQMKPDASFLFGSKLERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSM--TSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDED-EDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHG-VPSD--------------------------------------SSLGHSSLISYLVTLPSIRVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEECMLPSEPSSSPRDFSPSSHHSSPGYDSSPCRDNSP--KRYLIPKGDLSPRRHLSPRRDLSPMRHLSPR---------------------KEAALRREMSQRDVSPRRHLSPR----RPVSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYHNP-PLSMGQYL-------------------------QAEPIVLGPPNLRRGLPQVP-YFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQVRAP--IPMVPVGGIQMVHSMPPALSSLHPSPTLPLPMEGFEEKKGASGESFSKDPYVLSKQHEKRGPHALQSSGPPSTPSSPRLLMKQS--------------TSEDSLNATERE--QEENIQTCTKAIASLRIATEEAALLGPDQPARVQEPHQNPLGSAHVSIRHFSRPEPGQPCTSATHPDLHDGEKDNFGTSQTPLAHSTFYSKSCVDDKQLDFHSSKELSSSTEESKDPSSEKSQLH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7M4-1", "uniprot_id": "A0A8M2B7M4_DANRE", "id": "A0A8M2B7M4-1", "name": "", "aln": "------MEPHEPIVGQKCTKEQREKNPLQRKWVSEPSAGTKRNTFADPDIKRHSHREQSLTGGTNLTSSTQKYSSGNLMS-SAVTHSSQEGQFQQIF-----------------------------------------------------PRPYPYQLPHSYPQEPFLG----GTKPQPGLEAHAWSFSGQLQSLPPDDMYPVHSRSHG-VFPRH--------------------------------------------------------------------------------------------------------------------------------------------------------KSP---AGFGQF--------SQSGPEQPDESHKKEQKPKKPGKYICHYCGRACAKPSVLKKHIRSHTGERPYPCVPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFSDLAT-RTDTDQASSVGEAEAHSDGEQSTDTDEETAEGAMFPEKCSPQISFESDKSPMER-------------GPAYADPAEELSVASMKVPILIVPKQGVPSPATECPQFTDIKGSVIGGQMGRGDESHTVKQRLALR-----------------------------------------LTEKKDL---DSEQSQNLLSPHSKGSTDSGYFSRSESAEQ-QISPPNTNVKTYEEIMFGRT-WYHRTNSRSRQSVTVG------------MVAIASQDT---NINKSSAMQELAMGKISEG-----------HVFYQSDCAESHLIPG---CDPKHYHAGSCQTSTGLLEAP---------------------SDSGPLIRSNSMPTP----SPTN--LNVPPNLRGSHSFDEMMT-QDDVFYTGAAG-----LKR---LRRQSAFEH-SVQEGHGESESY-----------------------------GKITGPNSSLRGHLMPELKGSGSEMACPEVRTAYTSYG-----------------TKVG------------------MTEFTTRKRRMKKSVGEEEDCLGQDDGSRSGST-EMAEEYDLRQGSQDSSKAVPANKGSMFRAHSPSDSFD--------RGSCMTPEDVVHVQDSD-------TKTGGNVISVIQHTNSLSRPNSFEKTESIEHPFYQPDKHAGHLSEQSDTENIDDVQSPDSHHRSESMEHQQQGDNEHGS---------FSSNTLYHMPHKLVRQPNIQVPEIRVTEEPDKPEKEPEVPAKEPE----KHVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTCTSLSRSPSQESNLSHS-SSFSMSFDREESIKSVSPTKQDEFAKQSEFLTVPGSGHSLSIPG-HHQREMRRSSSEQAP--SALPTEVPEIRSKSFDYGSLSTGSRQ-------------GEVYASASAMKERRRGYLVRQASLSVYPEVVVQEPISELSIKQEHSDHVSQAGLTGTSY---CVANDLPRPRRGAQSVLGS---------HLLLQQSISEDSQSEDHFQNTPRLPAQLSSDSEHSVHEHMT--QDLFQHSSLQSSMASSPFLPFQPMLWHPESTQRNKHNLAFQSHNLQKL----------------HIKQPNLQPLLQKPYQPSHQIQVQTDSKTDG---ASHNYPYPSRASPQQLGVLSSKVLTTS---------FLQQVQPTFATQNVGSPQSLPGMLVPVRIQTNVPSYGSVMYTSVSQILVTHAQSTTSIRVICTDNVSTASITGTASKH----QVGINLSKILGHSGGSINFPTWKVPEYLPGSLNTGIPLSLTSGTISTTDASSNIGGSKRMLSPASSLELFIETKQQKRVKEEKMYGQIVKELSAVELSNSSAPKDNESTKAEFSNRD----DSIDEQERMSSSPPSDFLSSKYLGYPSAPR--LPDVPPKDNFIP------PLQIITNVTSRADSPEELDVDESTPEASSSPQSVMSSSDTQEESKQSMGNKFPVNMLVQLAANQGGGVVGSTLMLTDLADVHQFFQFPSLRTPTSVSWCFLNYTKPNYAHTTPLSS-VYGSWCISSYNPNPLNLSTKATLALLRSKQRKNT--EMYTMAAMHQPGTGKLVSSLRWKQKFEQLKPEHIQLDVGKFAKKMKGISSRDRGK-EDHGEKEACSKQAEPTRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKFCNFAFKTKGNLTKHMKSKAHMKKCLELGVSV--TSVDETEAEELDTTEEVQRGSEKKGMSEIMAEHQFSDADDSEGAEEDGDEVDDDE-DDDDDYEGDSTPKTRSRSTSPQPCSIPSLAITAIAASQESIPEG--------------------------------------LAISKQPIFTYFTSLPSIQITQLMAPSEKAGEIQMAEYQKLLQG--ALGEDHKNRLDVPSSMDEDLALSPEHSSSSFEFS-CSRLSSPGCDSSPLRESSPSSRRYLSPRRDLSPRGRLSPRREASPLRHISPR---------------------RDVYRRDLSPRRDLSPRGHLSPISQTGRPTSPGRDLSGR--LSPRSRR---GMIRPVSPRRGLHYQSGPWALSPSP-------------------------HAEMISLSQKTKGHAEPEMD-QRKTSHLQGDPRNTDAPSINQG-----LFSHLPLHSQQQIRTP--FSMIPIGGIQMVHSVPTSVTGHAHSTRLPLQKSTSEESSTSEVSFHLSEGRGPASKGSEDSPQSQEKSTSPKAPS----LSPQK--------------SREDSTEMSDKESKQEECIQTCTKAIASLCIASEETTDR---QPLPIDPYHQRTLSQSPAAQQDCAARAQHYCSSEISHPLHSRAESSVSATSKTPTASHPTLYNTETAERVSGQQSRGERPATIKKSKDSKDNR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PEH8-1", "uniprot_id": "A0A8M9PEH8_DANRE", "id": "A0A8M9PEH8-1", "name": "", "aln": "---------------MEATKTSGEVESSE-----------QIISFKDDEKHLPSEMTQ----------------RGQSSGSEDKIRLAEQPQTPSVS-----------------------------------------------------PSP--------------------------GIEPQVLASGNTLTSKSKE---QSHVQLRRKNVPLP--------------------------------------------------------------------------------------------------------------------------------------------------------NKRYLQAEYEML--------SGG-------LHKKEQKSVKTGKYVCQYCGRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHTHAVKAGLVSVSEQDCKNTDEVA-----EGEMHSDAEQSSDTDEEVAEDLSLDTTSHIKETEGYVQEKVG------------------KLAKKEALFPSQTP----LKKETGPSGKVSLWQFREMTAPVAIAQIDQMVEFSTIKQKLALR-----------------------------------------LSEKKSQ---ESDQSLSLPSSYSKGSTDSGYFSRSESAEQ-QINQSSASAKSYQEIMFGK---CYRPATRPKQSITVQ---------------TCMTDI---NEATSSFMITLNKGMMPGDT---------DSSIHRSKKDLVRSIKIDSESFQEEDYQECQIPSSDLLETA---------------------LESSVFLRSNSLPTS----SKSN--LNTPQGLRSSNSFDERMT-GADVTYRGAMG-----MRR---LMRQSAFEH-SANEGHAESDCY-----------------------------THLACSLKS-DLKIHSIDDSKMAAENFQETETCSVCPG--------------------------------------HSSESSTRKRRKDKTVTEEEDFHIQD---KPSNVTGLSEDLETKQISSDSVVS-------------DT---ER--------------------------------KAGSNVISVIQHTNSLNRLNSAEKLS--EVRSHQLDKIG---------KFMEKGHSMECHRTGSECQWGPCG----------------FLHQKLHMHKQPTSQPNIQVPEIRVTVEPDRPEKVPDVGVKQRE----KHTEEFQWPQRSETLSQFPMEKLPPKKKRLRLAEMECSSGESSFESACTSLSRSPSQDSNLSHS-SSFSQSLDREETLNLVSQINPDESSKPLEFLSVPGSSQS-------HHREMRRSASEQAP--YKLPSEIAEFRSKSFDYGSLSPSS------------------TYRLEEVKERRRAFLVRQASLSGEPETQGGNFSDEISKR-----------------------TTLPFTPEGSI-----------------------------EKMRYSLISGSSFPHHR---------------------------QYSPVQSSSQHVKPTVCNVHDMENVMLVIKKE----------------PEESKSPETYVNLREPQEDCSQSLGN--------------------------------------------VLSTIAVLSQAQQALASQCSSGLLVPVRIQMQVPSYGNITYTSISHILD---------------SHIQKPIS------------------CLEHKKSSSQSQQLHSLQASPAKLKTGIPLSLTS-KTISTTEAPSGGANKRMLSPASSIELFIEAKQQKRVKDENIYGQIVEELSAVELGNLEVEKE---------------------------SPKSEFTS-------------------------------------------EPIDKMDMDEATQEFYSNAELQS-SARISQDAAIMEQKPTPESMMASHHS-----ASCISLMPSAITGTLLFSKFPGLHTTTCMSWCYLNTTKPNSTHTVAPFS-EYASWFVRCHNPNPPDISTGMVLALLRSKQQRQN--AIYTIATIYQP--GLLVTSTPWTPKQEQIALDYREED-TKQDIRLR--EISHRGK-SLREDVSSIIRQTEPMRVKIFEGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHTDVRPYICKCCNFAFKTKGNLTKHMKSKAHMKKCLELGVSP--TAMDNTEDADDTQKSLGIMPAEQT------IKHQFSDVEDSDGADEDEPDEDEDD-ECD----GDSTPKTLSRSTSPQ---------------------------------------------------------------------SYAVNKPCMSGCLPKHFDSGCN-------------------LPKEQLEA-SSLTIEDDLNSDQSSCSFELCPPQLLS-------PCWDSPR--QRYMSPRGDLSPQRHLLSSRDSSPLRAVSPR---------------------RDLSIR-----GDFSPIRQLSPVR------PTGLDTSGQRAQSPLGRHK--VALRAVSPRRGSYQHRTHMDLGRSV-------------------------RFQASPIRP---IIGETGVD-QGDTSLNLIVPVGLCSSKDLPKTRQPDIFSHLPLHSQGQVSTP--VPMVPIGVLRMPSISTSGAVAERNS--LPSIPQGNILETAAPGQTSASVPDPAVAYSGEIATYS---TGLP---------------------------------NKDDKK---EESVYTCAKAIASLRITSEDASDN---PPKS---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZRB5-1", "uniprot_id": "D3ZRB5_RAT", "id": "D3ZRB5-1", "name": "Transcription factor HIVEP3", "aln": "--------------MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSTPYPGSSTTASSEGASQELLAPQPFSGPSVALREGAQEKTGQQQKPPRR-----------------------------------------------------PSIEASAHIPKLPQHPLTPAFMSPSKPEHLLEGSTWQLVDPTRPGPSGSFVAPGLHPQSQLLPSH--------------------------------------------------------------------------------------------------------------------------------------------------------ASILPPEDLPGIPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTDSEEETGATSGPSTDVLPKSKHPLLSSSLY-------------------------SSGSHGSSQERC--SQSSTAPSLEDPTPFAEASSEHPLSHKLEDTHTIKQKLALR-----------------------------------------LSERK-----KLIEEQTFLSPGSKGSTESGYFSRSESAEQ-QVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSAEDKPSLVPLSVPRTQ---VIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRESLSSHGEKTKQEQSLLSLQH---------------PPSS-----THPVPLLRSHSMPSA----ACT--ISTHHHTFRGSYSFDDHIADPEVPSRSTPVF-----TSHPRMLKRQPAIELPLGAEYSSEEPGP-----------------------------SSKDPITKPSDEPEPKESDLTKKTKKGLKTKGVNYECTICG-------------------------------ARYKKRDNYEAHKKYYCSELQITKAHPAGAH---EVEKTQAEPEPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPGFS-------SPGPSDAAHNLPLESTKSPAEASKSVPTLEGPTSFQPRTPKPGSGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQPGSLE-EDKPLAPFSSPPPAP-----------HGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEP-----EKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESSISLSGSSRSASFDREDHGKAETPGPLSDTRSKTLGTHMLTVP-----SHHPHAREMRRSASEQSPNVPHSS-HMTETRSKSFDYGSLSPTGPSV----------AVPAAPPPPAAPPERRKCFLVRQASLSRPPEAELEATPKGKQESSE-EPSASKPSTKSSMAQIS-VATIQGGLSGSKSQMQDRPPLGSSPPYTEALQVFQPLGTQ--------LPPPVSLFSLQQLLPQEQEQSSEFFPTQAMAGLLSSPYSVPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPSTLS-GYFLPLQSQFALQLPGEIESHLPSIKTSLPPLATGPPGPSSSTEYSSDIQLPPVTPQATSPAPTSASPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGSSTSMALTKYEEPSSKSMTVCGAD----VYEAEPGPSSISKEQSRGFQTPYLRVP----ERKGTALSSEG-ILSLEGCSSTASGSKRVLSPAGSLELTMETQQQ-KRVKEEEASKADEKLELVSTCNVVLTSTEDRKKTEKPHVGSQGRSRRETETLSCLSSDVSDPKELSPLSQSTLS------------------------------HGTAPGSEALKEYAQPSSKAHRRCLPPLSVKKEDPK---EQTDLPPLAPPSSLPLSDTSPRPAKLQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSK--ETYTMATAPHPEAGRLVPSNSRKP---RMTEVHLPSMVSLESQKDPARVEK-EEK---AEEGTPTSKRGEPTRVKIFEGGYKSNEEYIYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCRHCHFAFKTKGNLTKHMKSKAHSKKCQET-------GVLEELEAEEGTSDDLLQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEEESQDELSRPSSEAAPLCLPATLQEDSSLIRGPQPPDATS----------------------------------------DAAPRGSSISEATRLTASSCSTPSQGTQGLPRLGLAPL---EKGTSSALSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKTDSSPQRCSPAR-AQASVASTPGPQTGPGRDLSPHLCGSPRPELSCLTPY-----------PIGREVP------AGLESATVTGTPRCSPTRRRSLGRAESSPPHTVLPGTWALGGPCSPSVDKYGLGLGPVPRALLQPVPLPHTLLSRS-------------------------PETCASAW--TESRSPSAGP---APLSSRPSSAPHDFHGHLPSRSEENLFSHLPLHSQHLNRTP--CPLIPIGGIQMVQARPGAHPTLLSGPCAAWVSGFSGGGSDLTGAREAQERSRWSPTESPSASVSPVAKVSKFTLSSELE---------------------EERTSRGPGRP-PAWEPHRAEAPAETMGTHSPCPP-----QLPQGHPLAPSWRGLLESPHALANLKASSFPPLDRSSSMDCLAETSTCFPPRSRNLSGEPRTRPDSPELLGSGELRTPLFLSKDSGPPSI-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A884-1", "uniprot_id": "ZEP3_MOUSE", "id": "A2A884-1", "name": "Transcription factor HIVEP3", "aln": "--------------MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSAPYPGSGTTAPSESATQELLATQPFSGP-------SQEKTGQQQKPARR-----------------------------------------------------PSIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH--------------------------------------------------------------------------------------------------------------------------------------------------------ASILPPEELPGIPKVFVPRPSQVSLKPAEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTDSEEETGAASGPSTDVLPKPKHPLLSSSLY-------------------------SSGSHGSSQERCSLSQSSTGPSLEDPAPFAEASSEHPLSHKPEDTHTIKQKLALR-----------------------------------------LSERK-----KLIEEQTFLSPGSKGSTESGYFSRSESAEQ-QVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSSEDKPSLVPLSVPRTQ---VIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRDSLSSHGEKTKQEQSLLSLQH---------------PPSS-----THPVPLLRSHSMPSA----ACT--ISTHHHTFRGSYSFDDHVADPEVPSRNTPVF-----TSHPRMLKRQPAIELPLGGEYSSEEPGP-----------------------------SSKDPTSKPSDEPEPKESDLTKKTKKGFKTKGANYECTICG-------------------------------ARYKKRDNYEAHKKYYCSELQITKAHSVGAH---EVEKTQAEPEPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPAFG-------SPGPSETAHNRPLGSTKSPAEASKSAPSLEGPTSFQPRTPKPGAGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQPSGLE-EDKPPAQFSSPPPAP-----------HGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEP-----EKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESSISLSGSSRSASFDREDHGKAEAPGPFSDTRSKTLGSHMLTVP-----SHHPHAREMRRSASEQSPNVPHSS-HMTETRSKSFDYGSLSPTGPSL----------AVPAAPPPPAAPPERRKCFLVRQASLNRPPEAELEAVPKGKQESSE-EPAASKPSTKSSVPQIS-VGTTQGGPSGGKSQMQDRPPLGSSPPYTEALQVFQPLGTQ--------LPPPASLFSLQQLLPQEQEQSSEFFPTQAMAGLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPSTLS-GYFLPLQSQFALQLPGEIESHLPPVKTSLPPLATGPPGPSSSTEYSSDIQLPPVTPQATSPAPTSAPPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGSPASTALTKYEEPSSKSMTVCEAD----VYEAEPGPSSISKEQNRGYQTPYLRVP----ERKGTSLSSEG-ILSLEGCSSTASGSKRVLSPAGSLELTMETQQQ-KRVKEEEASKADEKLELVSTCSVVLTSTEDRKKTEKPHVGGQGRSRREAETLSSLSSDVSDPKELSPLSHSTLS------------------------------HGTAPGSEALKEYAQPSSKAHRRGLPPMSVKKEDPK---EQTDLPPLAPPSSLPLSDTSPKPAKLQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSK--ETYTMATAPHPEAGRLVPSNSRKP---RMTEVHLPSLVSPESQKDPARVEK-EEKQGKAEEGTPTSKRGEPARVKIFEGGYKSNEEYIYVRGRGRGRYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQET-------GVLEELEAEEGTSDDLHQDSEGQEGAEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEE-SQDELSGPCSEAAPPCLPPTLQENSSPVEGPQAPDSTS----------------------------------------DEVPQGSSISEATHLTASSCSTPSRGTQGLPRLGLAPL---EKDMSSAPSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKNDSSPQQCSPAREAQASVTSTPGPQMGPGRDLGPHLCGSPRLELSCLTPY-----------PIGREAP------AGLERATDTGTPRYSPTRRWSLGQAES-PPQTVLPGKWALAGPCSPSADKSGLGLGPVPRALLQPVPLPHTLLSRS-------------------------PETCTSAWRKTESRSPSAGP---APLFPRPFSAPHDFHGHLPSRSEENLFSHLPLHSQLLSRAP--CPLIPIGGIQMVQARPGAQPTVLPGPCAAWVSGFSGGGSDLTGAREAQERSRWSPTESPSASVSPVAKVSKFTLSSELE---------------------EERTGRGPGRP-PDWEPHRAEAPPGPMGTHSPCSP-----QLPQGHQVAPSWRGLLGSPHTLANLKASSFPPLDRSSSMDCLAETSTYSPPRSRNLSGEPRTRQGSPELLGRGELRTPLFLPKGSGPPSI-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T1R4-1", "uniprot_id": "ZEP3_HUMAN", "id": "Q5T1R4-1", "name": "Transcription factor HIVEP3", "aln": "--------------MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKR-----------------------------------------------------PPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH--------------------------------------------------------------------------------------------------------------------------------------------------------ASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLY-------------------------SSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALR-----------------------------------------LSERK-----KVIDEQAFLSPGSKGSTESGYFSRSESAEQ-QVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQ---VIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQH---------------PPST-----APPVPLLRSHSMPSA----ACT--ISTPHHPFRGSYSFDDHITDSEALSHSSHVF-----TSHPRMLKRQPAIELPLGGEYSSEEPGP-----------------------------SSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICG-------------------------------ARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAP-----------HGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEP-----EKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVP-----SHHPHAREMRRSASEQSPNVSHSA-HMTETRSKSFDYGSLSLTGPSA----------PAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGAD----VHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSES-ILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQ-KRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALS------------------------------HGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSK---EQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSK--ETYTMATAPHPEAGRLVPSSSRKP---RMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQET-------GVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE---EESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASG--------------------------------------TEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLC-----------PLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAES-PPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRS-------------------------PETCASPWQKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAP--CPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYP--------------KERERTGGGPGRP-PDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7V2-1", "uniprot_id": "F1Q7V2_DANRE", "id": "F1Q7V2-1", "name": "", "aln": "--------------MEALHSQATTGEQSG--------GLAKQNETPVDNPKP----------------------------------------QYHEE-----------------------------------------------------KKVVTQVHHAQQRKHLNIERKRLRLQRKSLQERDVVEEGKPPRASGSSEHLNANMS-QAREMPSG--------------------------------------------------------------------------------------------------------------------------------------------------------ASSSAVSAKP--------SCSMEEVLEGTPRQKRERKPQKPGKYVCSYCGRACAKPSVLQKHIRSHTGERPYPCAPCGFSFKTKSNLYKHRKSHTHRVKAGLTADREG----PGISCSEEPLTDSDEESQPSSYLEKQRMSVQNSSATERCSEGQ------------------------------------------------------------------------LQEIEDSHAVKKRLAMR-----------------------------------------LSRGRRTPLGSSDEASSSFGQSSKGSTESGYFSRSESTEVSQDSPPNTSAKSYAEVILGKFGRLGH---LQRTSHQQHAHPAGQEGKR--IPFNVPKKQ---VIDHITKLITINEAVVDTSKIDSVKPRRFSLSRRSSTELKVVSSKEPFLHSPKEIDISAKSSGSITLGVPCEKFQHHSLSIPQTES-----TSTAPLLRSHSMPSD----ASTSDVSETSRSLRLSQSFDD----------PQPIQ-----NRRHGMLRRQPAIELPIGAELTMEEQSY-----------------------------STSSFHHPVTTMPDPSQ-------------KQEQFECGACR-------------------------------IVCNDVERYQKHKQHCCTVHISQQSE---------------IPVYQVDESTRTFTSRSGAFAFRKRRKEESIEFED-------------------------------PSLPSVSYIPLRGYAPSCEQPIKRTHELGQEYCTEGSLKGISVIQHTSSFEKHDNSKTD---EPSHTHGVSHTSPHPQT-----------KQQATKLSFRKLVRQQNVQVPEILVTEDSNTEAMAVSPPPIVPKMKDTEKVSEFQWPQRSPTLAQLPIEKLPPKKKRLRLAEAAQSSGDSSFES--MSLPHSPSQDSCTSHN-SSRSTSFEEAGKADADLTP-----TRRSRATHTLTVP-----INS--HREMRRSASEQAPHIPQTANLITEIRSKSFDYSSLSPD--------------------RTPAGWKERRKCLLLRHSAVREPEEEDQTTKVFN----------TSSPTCRTSTSPSHSPVTSYSPSTHHVSSSNTVHSFGEK-----------------------------QIMKSQDVLSEN------------------TQLSTLQLTPVIHTDHPTTVG--------------------------------SLICPSGAARAHYSSMSTGLKLEIPMEKD--------------------------------QPYITHCHQHQNIGFDVTSNPEVLRPLPAQSIPVRLNSHLPYHAGSIYTTVSQTFFSRPQ-----------EPCCSGVSSVAVVS----KYEIMDQQPDSERSD-----------------------------------SVSVGATKRVLSPTSSNELNPESEQQQKRVKEEEENQENERRD----------------------------------------------------------------------------------------------DKVLIEFKKEEILGEQSVIFPTEHKDP------------------------------------------PFQTLNTNLTFSWCFLNYIKPNPSIQSEQQNSVYSSWCTSTRNPNPPGLTSKEMLSLLQCRQRHET--LLYTMASMSPSLDVKQETPDSQKP---NVTEVHAAQLTEPKEAQQAELTEVETKTTEEKEDQLSTSKCS--SRVQICEGGYRSSEEYVYVRGRGRGRYVCEECGIRCKKPSMLRKHIRLHTDARPYVCQHCNFAFKTKGNLTKHMKSKAHGKRCPEG-------PAPGPVQCELET-DEGGDSAKHFLETEEVEEHQFSDAEESDDEAEDNDEGDEQT-----------------------------------------------------------------------------------SCSSSSSKWTSISRDDSGSCDILGLSNPGWEQHPKPPVS--------------MSPRKPSHYGEASSPKTTKSIVTLLHLDPTTGMCSSPIRSLSPGLQMSPALPQSPGRDMSPLRCPSPRLSLSPSSCLSSLS-------PSD-------------RSTSSFSERRVSPIRDLSPIRPSS--PSCPLALTVGASVTIQYQADRPRASTKASPNRLNLKKKTEKTHSPHR-------------------------RTNMTQSWPPAHGR----------------------LSRNMQPREGQRVLSHLPLHSQPQVMIPNLSLTIPIGGIQMVQPRS-------------------------------------NMLLRSTSLNHSVAQMTVTVLTKEKG---------------------AGRSPVGEVPH-RKNQLIVFTEPAVEMSSKSEASS----------DEDKEQIHGVVQAELFSRKKEVPSVAMTTWKSISQKNNRKHSRSPKKTQPVDGSRTSMDAKC------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M9H4-1", "uniprot_id": "F1M9H4_RAT", "id": "F1M9H4-1", "name": "Zinc finger protein 40", "aln": "MPRTKQIHPRN--LRDKIEEAQKELNGAEVSKKEILEAGVKGASESLKGVKRKKIVAENHLKKIPKSPLRNPLQTKHKQNTEEPLFSALQSAPESHKKHNCVPVKQGRQFTKQNGETPGMTVEASESGDSVSPKKASSPHHRSELRRWRSEGSDPARLSGLDGQRDSSSSSSKTRTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAVKTEKPRPNRTVRSPSKLKNSSLDAPNPASPELVAESQCSPCTSYPVPVASTQKSEQVAAQRVSHLHSQYDHLVPKPGQQNPQLPGHLGLAGSLTNPHTHENTKLEPIYNIAMTSTVGLASPSSRTQVTPPHQQ--MDSVSPSSVSPATSTQSPPGPIYSSTHVASVVSQSVEQMCNLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGPGDGRQNDPSVRDLQPVQIMKMPSDPEALPKS--IASRADHVVSGFSSQDRPSESQALTELPKVVVHPVSMSPLKTDSVQVASPKPELPSTQSQKDLHAASRLSHSA-----GVSSLETDETCHQKGDVTLSEGKPEPHS--GAAHAQLQRQQATDDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQ-AMSPPTPFARTFPTTDPDPAKNSGPAGPRISAPAPAALAPGEKSSVVAGQMRPPLATK--TLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVP----SLDCLPITRSNSMPTT-GYSAVPANIIPPPPPLRGSQSFDDKIGTFYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASENHVLGSGQSVDESCQGCPASSEPGPVQSKAANT-PHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTK-VAAREPEHGLAPGGVQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDDEDLQPRESGRSPESAEALQLQPVPGSAPSPSKQAPATAGDQAHRGVQLQSSPVQLVARVPEQALPLKQCPVVEQQLNSATQDRIEVQRQAGGISVIQHTNSLSRPSSFDKLEPLEGGTAFSLQELGRAGMPGALKVIGMPPEEGHPPRD--ATHQIALS-------RESARKIPSERFVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHD--------EEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFEST---LSRSLSRESSLSHA-SSFSASLDVEDISKVELSPKTDFPSK-AEFLFIPLGSNTLS--VPGSHREMRRAASEQISCVPTLMEVS-DFRSKSFDCGSIAPSHVVPALVEPQPSNSPSGVGGTGHVPLLERRRGPLTRQISLNIASDSPLSPGSVSALQTIVLP-GVNAIPLQALRPPDVASADLPAHTVPSQALAKDLQAEMSSCSSTDTFPPQQLFGAH--------LLNKTNMPLSHQNTPLPLPVSVQGGKPGAPPPAGTSSTGDGSFAPKYQLQCQAFTSGRGCSSSPLHSLPN------------------PVLPDQTAADPCTASVALSAKAVDPVSKS---------------------------------------YPLPSLELGLPSD-QVQKRLPSFVLPVLQPRDVPVYCLSTVTSLPQILVTHDLSNTPICQTNQSIVPVSEEQNPMPKS------QNYLQNALPTPEKDLACKTVLSEMGQNAPVSESSATVQKVSAGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRPLELPSSRANEGHKQKKPVLVRQLCTVEPLEGTALEQDPGSASGKSS-RNADSTQVLSTD-----------SLSSRHSMFAVPDHVSEFQEFKNTKLSTSLTPTVGSSHIPLESACVLPLKSRDDNQEKGSSGVQNEENKV-IQGQRQPPIPGLSVLSSSDTQQPSFPSLKTATSFTWCYLLRQKSLPLAQSDQKTSAYAGWTVSPSNPNPLGLPTKVALSLLNSKQKTGK--SLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATIVEFSNKDDSEINSEQDK-----ENS--LIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLG-----ISVGLIDEQDTEESDEKQRFG-CERSGFDLEESDGPDEDDND-NEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEDLRVSSCFS-GVHTDP------------------------------------------MDILPRALLTKMTVLSTVQIDPNRTDLT-AKARQNTGKDELELAPPVDTPISPEVTPRSPGHQMSVHYSESD-ALRSPAAGNTVAS-----IQDSPSVGLPPATIAQLNPQPAARISSSVSPHPESQEP------------------KQQITLQPSPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLT-YSTFVPIQAGPMQLTIPAVSVIHRTVG------------------------TPVDTITEVSGATNRPTGVAE-LSSVVPCIPIGQIHVPGLQNLSPPALQSLSSLGMETVNIVGLAN-ATVGPQVHPPGLALNAVGLQVLANAP-AQSSPATQTHIPGLQILNIALPTLIPSVGPVAVGT--AGTPETATSNSKTVEPQTP--------------------AGQGHSAEPPQRLPEGPQETPQTVP---GPSVDHARP-DGSSKMDTKKVASASHVLPGR--SSAQAQPAPIPEALQKIV------ASGPTSLPTDRPAPRP-PVPHRQPIVHFSDVSSDDDEDRLVIAT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03172-1", "uniprot_id": "ZEP1_MOUSE", "id": "Q03172-1", "name": "Zinc finger protein 40", "aln": "MPRTKQIHPRN--LRDKIEEAQKELNGAEVSKKEVLEAGVKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQTKHKQNTEEPPFSVLPSASESHKKHNCVPAKQGRQFTKQNGETPGMTAESSESGDLVSPKKTSSPHQRSELRRWRSEGSDPTRLSGLDGQRDSSSSSSKARTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAIKTEKLRPNKTVRSPSKLKNSSLDAPNATSPDLVVESPCPPCTSYPVHVASTQKSEQVAAQCVSHLYSSQDHLVPKLSQQNQQLPGHLGFTGSLTNLHTLESTKLEPIYNTAVTSTVGLTSPSTRTQVTPPHQQ--MDSVSPLSVSPASSTQSPPGPIYSSAHVASVVSQSVEQMCSLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGLADGRQNNPCVKDLQPVQTMKTVSNPESLPKL--IPSNSDHVVRGFSSQDRPSDSQAPTELPKVVVHPVSMPPLKTDCLQVANPNPELPSPQSPRDLHVASILSHSA-----SVSSLEMDESCHQKGDVIQSEGKPDSHS--GTAHAQLQRQQATEDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQ-AVSPPTPFARTFPTMDPDPAKNGGAPGPRISAPAPSALATGEKSSVVTGQMRPPLATK--TLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVP----SLDCLPITRSNSMPTT-GYSAIPANIIPPPPSLRGSQSFDDKIGTLYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASESHVPGSGQSVDESCQGCPSSSEAGPVQSKAAQT-PHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTK-AAVREAEHGPAPGGAQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDEEDLQPHESGRSPESADALQLQPVPGAAPSPSKHTSATAADQAHRG-------VQLVARGPERALPLKQCPMVEQQLNAAAQDKMEVKRQGGGISVIQHTNSLSRPNSFDKPEPLEGGITFSLQELGRTGMPGALKVIGMAPEEGHPPQD--AMHQTALSHNLRGEPRESARKIPSERYVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHD--------EEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFEST---LSRSLSRESSLSHA-SSFSASLDLEDISKVELAPKIDFPSK-AEFLLIPLGSNTLS--VPGSHREMRRAASEQISCVPTLMEVS-DFRSKSFDCGSIAPSHVVPALVESQPSYSPSAVGGTAHVPLLERRRGPLIRQISLNIASDSHLSPGSAAALQTIVLP-SVNTVPFQAPRLPDMASADCPAHTVHPQALAKDLQAEISSSSSTDTFPPQQLFGAH--------LLNKTNTSLSHQNTPLPLPVSAQGGKPDAAPTACVSSTGEGSFAPKYQLQCQAFTSDQGCS-APLRSSPN------------------QVLPGQAGADPCPASEAPPAKAADPMAKP---------------------------------------CPLPPLELGLPRDEVLQKQLPSFVLPVPQKRNVTVDCFTPVTSLPQILVTQDLPNMPICQTNQSLVPVSEEQNSMPKS------QNYLQNASPTPEKELACKTVLPEVGQSVPVSESSPTVQKVSVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRALELPSSRANESHKQKKPVLVRQLCTTEPLEGAALEQGACSASGRSSNKAANLTQVLPTD-----------SLSSRPSTFAVTDHVNELQEFKNTKVSTSLTPTVGSFPAPSESACVLPLKSIDNNQEKGSPGVRHEENKV-IQGQRPPLVSGLSLVSSSDTQQPSFPSLKTATSFTWCYLLRQKALPLAQNDQKTSAYTGWTVSSSNPNPLGLPTKVALSLLNSKQKTGK--SLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATVVEFSNKDDSEINSEQDK-----ENS--LIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCSYCNFSFKTKGNLTKHMKSKAHSKKCVDLG-----VSVGLIDEQDTEESDEKQRFG-CERSGYDLEESDGPDEDDND-NEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEELRVSSCFS-GVHTDP------------------------------------------MDILPRALLTKMTVLSTVQSSPNRTDLP-AKARQSTEKDEHEQAPPADT-------PRSPGHQLSVHSSESD-VLRSPAAGNPAAGSPGAAVQDS-SVGLPPA-VAQLNPQPAARISSSVSPHPDSQDQ------------------KQQIILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLT-YSTFVPIQAGPMQLTIPAVSVIHRTVG------------------------TSGDTITEASGSPNRPTGVAE-LSSVVPCIPIGQIHVPGLQNLSPPALQSLTSLGMETVNLVGLAN-ATVGPQGHPPGLALNAVGLQVLANAP-AQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGT--TGTPETTAPNSKAMELQMP--------------------AGQGHSAEPPQGSPEGPQETPQTVS---GPSADHARP-EDSTKMDTKKGPSAGHVLPGR--SPAQAQPAPTPEALQKVA------TSAPPSLPTDRAAPRP-PVPHRQPIVHFSDVSSDDDEDRLVIAT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15822-1", "uniprot_id": "ZEP1_HUMAN", "id": "P15822-1", "name": "Zinc finger protein 40", "aln": "MPRTKQIHPRN--LRDKIEEAQKELNGAEVSKKEILQAGVKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQAKHKQNTEESSFAVLHSASESHKKQNYIPVKNGKQFTKQNGETPGIIAEASKSEESVSPKKPLFLQQPSELRRWRSEGADPAKFSDLDEQCDSSSLSSKTRTDNSECISSHCGTTSPSYTNTAFDVLLKAMEPELSTLSQKGSPCAIKTEKLRPNKTARSPPKLKNSSMDAPNQTSQELVAESQSS-CTSYTVHMSAAQKNEQGAMQSASHLYHQHEHFVPKSNQHNQQLPGCSGFTGSLTNLQNQENAKLEQVYNIAVTSSVGLTSPSSRSQVTPQNQQ--MDSASPLSISPANSTQSPPMPIYNSTHVASVVNQSVEQMCNLLLKDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPDAGGLFLSHESPKALSIHSDVEDSGESEEEGATDERQHDLGAMELQPVHIIKRMSNAETLLKSSFTPSSPENVIGDFLLQDRSAESQAVTELPKVVVHHVTVSPLRTDSPKAMDPKPELSSAQKQKDLQVTNVQPLSANMSQGGVSRLETNENSHQKGDMNPLEGKQDSHV--GTVHAQLQRQQATDYSQEQQGK-LLSPRSLGSTDSGYFSRSESADQ-TVSPPTPFARRLPSTEQDSGRSNGPSAALVTTSTPSALPTGEKALLLPGQMRPPLATK--TLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVP----SLDCLPITRSNSMPTT-GYSAVPANIIPPPHPLRGSQSFDDKIGAFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTK-VAMREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQQNESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGISVIQHTNSLSRPNSFDKPEPFERASPVSFQELNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPSRLVRQHNIQVPEILVTEEPDRDLEAQCHD--------QEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDST---LSRSLSRESSLSHT-SSFSASLDIEDVSKTEASPKIDFLNK-AEFLMIPAGLNTLN--VPGCHREMRRTASEQINCTQTSMEVS-DLRSKSFDCGSITPPQTTP-LTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNTALP-SVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAETSNSSSTNVFPVQQLCDIN--------LLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQLHCQVFTSGPSCSSNPVHSLPN------------------QVISDPVGTDHCVTSATLPTKLIDSMSNS---------------------------------------HPLLPPELRPLGS-QVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNHSVVPISEEQNSVPTL------QKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQVCTTEPLDGVMLEKDVFSQPEISN-EAVNLTNVLPAD-----------NSSTGCSKFVVIEPISELQEFENIKSSTSLTLTVRSSPAPSENTHISPLKCTDNNQERKSPGVKNQGDKVNIQEQSQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTWCYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLPTKVALALLNSKQNTGK--SLYCQAITTHSKSDLLVYSSKWKSSLSKRALGNQKSTVVEFSNKDASEINSEQDK-----ENS--LIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLG-----VSVGLIDEQDTEESDEKQRFS-YERSGYDLEESDGPDEDDNE-NEDDDEDSQAESVLSATPSVTASPQHLPSRSSLQDPVSTDEDVRITDCFS-GVHTDP------------------------------------------MDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSVDT-------SRSPCHQMSVDYPESEEILRSSMAGKAVAIT-----QSPSSVRLPPA-AAEHSPQTAAGMPSVASPHPDPQEQ------------------KQQITLQPTPGLPSPHTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLT-YSTFVPLQAGPVQLTIPAVSVVHRTLG------------------------THRNTVTEVSGTTN-PAGVAE-LSSVVPCIPIGQIRVPGLQNLSTPGLQSLPSLSMETVNIVGLAN-TNMAPQVHPPGLALNAVGLQVLTANPSSQSSPAPQAHIPGLQILNIALPTLIPSVSQVAVDA--QGAPEMPASQSKACETQPKQ--------------TSVASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARL-DGLSKMDTEKAASANHVKPKPELTSIQGQPASTSQPLLKAHSEVFTKPSGQQTLSPDRQVPRPTALPRRQPTVHFSDVSSDDDEDRLVIAT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PBC6-1", "uniprot_id": "A0A8M9PBC6_DANRE", "id": "A0A8M9PBC6-1", "name": "Zinc finger protein 40", "aln": "MNRQREIEETLSINTDKIEEAQKEFKDPKGAHKDTNESTGR-NSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPE-----------------DAEDGPEEVSASRTVKVEQEE------ISTSEPQALS-HKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIG----HLGKSASNPVTYSDYAVAMP---AVNFNIQSQNS-----------FMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQ----------------EKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSG--SLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVT-----VLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQ-AMSPPSPFVKITPPGDTDITKTPHIP-PCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNP-AVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATE----RNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLN-RNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTET-TPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILG------QIQIIARAG-ELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMS-TPKCPSQT-------HEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVEST------EKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESS---LSRSLSRDSSLSRC-SSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLG--VPG---IMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPP--STLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPH--------PWHQTSRVVAGHVQPLVHMVGGQTDIKKS------SDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQG---------------------TQIPLPVITIP-IANEIKGSHSNDGMQNV---------------------------------------YVAQSSYQAVLNK-------PSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQ-ESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAP-----------EQLPETLDTE-----------KNTQKPIPQVTTTEVSE-QEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVK-LASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKK--IHYTQAKTTTLKSDILTYSGKLKDVLPK-VLIQQRSVPSENSGKTKPDTQPVNQK-----ESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMG-----VAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPT----------------------------------SDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLG-----QDGVSSTISQP-ASECNANVDRGTQTSSDPLQGSLHF------------------PHAGPLHEPR--IGATTHLFSHLPLHSQQPPRSPYSMVPVGGIQLVPAGLAAYSTFVPIQAGPVQLTIPALSVIHRQTGSPL---------------------SAPNTSPRPDCSPTQPLVVQEPVSSVLPCFPLG--QVAGLQTLG-AHQTALQPVGLETLSVVGLANSTQLVPQQSLP--LNATLGVQVLAASPAPQCSTASPAQIPGLQILNIALPALIPSLSPLSALSPLPATQDKPRSPEGVASVTLP--------------------AQVAGSPPAPLPSASPPTANPGDAAVNAKPCMEVRKVSQNNPSVGSRDTGGAEKTTGMVEKSKAPPQPPSPCSPSLSNERG---CNVAHKGSAGEACEVKPRQPVSRQPVTDDYNEASSDDEDRLVIAT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8F4-1", "uniprot_id": "SCHNR_DROME", "id": "A1Z8F4-1", "name": "Protein schnurri", "aln": "----MARRKGSGRGKSTVNSRKSALETAREKTKDEPTANTSQDNKFDNNMENATTTTAKHYKTAGKQYKTNKVNNTRRATAAAAAAAAAAATTTVTT------------------------------------------------------AATPTKKRTYRETATATIVTQRSTNKANIAAAIALAAATEATASASASATATATDATLTASKAAAT------------------------------------------------------------------------------------------------------------------------------------------------------AAATTDAASGNS------NSSSKPSTSTRDKLGEVPLPTVDSNHIISNNNNNNNNNNTSNNNNNNHHSDNSISENNYEFKSRDKASLSDSKMTLQQMAAVSSNQEPVAPNVANTMSNSSIINSQQTTVNATPATDEAPLGDRSNISRYLHKKFKRLASTTEVDS--------------------WSATNGGGALQASGDAVRTTSLSSNSSLSPPPTTPLANGHHLMTQQQSHQQVQQQQQQQQ------------------------------------TPPPSVAIHEFSANFVNSNHVNAIGHEESIISNSGYKAAGRTRTPLANSNSNTNSTSNSNSNHAANATLSPASFAQHQQLTQPTTVSPGIPGGAAAPNPACEKSG-RYVCQYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSD-------------------QDAELSNSSSELPSRAGSPYEEPINSPTPSPSTLSAAKSAYIQQPPLPTYMQQLPLG---SPAAGTLPPTTADNHHSATAQHRQSIDYKP---------------------------YKPKFHNASLYSCSSKELQQQQQQLQIQQQQQQHQLAQQKLSIQLPLVQ--------QPSLAHPTLSPSTQMKMKHHINSHQIQLQLQQQQSLLAQQSLLAAMPPGGVYYLGQPSYYNQDTAAAIHQHALAIQQFQIHLAQQQQQQQQQHPPLVKATPPMQQPPSLPPQQLVRANSQISSVATAPATPTPAANLSTFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNASQHG--SNASALHANNSQNNTNAQMPERETKVNLAQAIFQKQQHQLQQQQQQQITQQQQQQLEQQNYYTYIQQQQECQQQQLEPPNGVVKRNAYKPGVVMTTPVKQQQQLPPPPSPLPMQTMQYRQDPATPVTKIEQPTTAVPVMPLNLSAKPKPTLVTVPVSSLSTSSLAPTPTTSTNPTSSSKTAPPPAQVNNSIIKNLLLNARGLAVPIGEGD-----------DAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASAPAPAVATVTAPSSAPAPQIEALRFVDAPLPSPGPLLGKTPLVDYAQQSTPRKAQDSVVITKMHEDRQFVIEAQP----------------AKRIKTSDLVVASSSQQPTSFNFSFNNQNSS--------------------------------------NSVPELQSSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVNNETGSSSKERKLMALVSGSG----LLGVSSGPQHFQFPPINSITAFNPLTLPPMSGGDKTTPVTPIPHVPGMPGPGSLTPQMPLLPPPPQQLQLPIPSSRGRSPNRKQPSPLLLGGGSGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKEAPKKAPFNFLRMADNVKTTEPEVRHFNLENVISGKQQELPLTPLHVDTPNGNAPEETSPVASASASAKSKFLRPTSLPLKPGTFTP-KRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGSGKLSYNLVASQQIVSSPSTSSTSSAFYQGPLKTPPTVTIAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYPQLQDTPLPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVANEESAPMDLTKPRGSILLISPSPVSVPAHDLPKSQAQQMHDVIFGTSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVQLQTYIKEHALHQAKIKQSQFSRSYLINTLYTAASPVMSSSSTLFTANSRPVMSVNEVPSIEVHEVKTPEAIESPRSAPEQAPVILAQIAQEENEEPNIAEPHNANLPAAVQQPDVNEFTGVLGNPTAPPTSSVTATSVSTTTAAPVAPSSTANSTQPAQRTVIVGEDGFKSSTPTSKSGDLQHVSYGRGVPPAPIAGDARPTCTMCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLQEKDPGKLSSYTTPSGMMQLAQDAAGPVSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHSLKRRLPGSFSSTGEESDNPPESSGEKRARSGQELPVPVAVPVAASAAASN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . .::: . : .. :: ..* .:.. . *. : *:.* . : : : . : . . : . . . ::*** : ..: . ... . * .:*: . : . * * : . : : . . : ::::.: . : . : . : : *:. : * ** : . :. . . . :: .: . : . :*.: . . * * : : . * :.: . :*.*. . .: .. : *. . :* : :. :*: .. ::* .:* * . : : ***.* *:* *:******:*:*.************:**** *:* **: * *:*:***********:**:* *:* : . . : * .:.: : . .. . . : . . ", "identical_positions": 82, "similar_positions": 161, "identity": "2.75%" }, { "cls_id": "homologset.agr.FB:FBgn0003401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQF4-1", "uniprot_id": "FKBP6_RAT", "id": "D3ZQF4-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MSVFSRLRNGIPPSRDDCQSPYERLS----------QRMLDISG---------------------DRGVLKDIIREG--AGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLN-LSFVYLKLDRP--AMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XW8-1", "uniprot_id": "FKBP6_MOUSE", "id": "Q91XW8-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MGGSTRDPGALEGAGILGQSPYERLS----------QRMLDISG---------------------DRGVLKDIIREG--TGDTVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRKGELARFLFKPAYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLATCEEQHLVEPAVLLVLLN-LSFVYLKLDRP--AMALRYGEQALLIDKRNAKALFRCGQACLLLTEYERARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSRSSVGGN------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75344-1", "uniprot_id": "FKBP6_HUMAN", "id": "O75344-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase FKBP6", "aln": "----------------MGGSALNQGVLEGDDAPGQSLYERLS----------QRMLDISG---------------------DRGVLKDVIREG--AGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLN-LSFTYLKLDRP--TIALCYGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMFAPCGDGSTAGES------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1I9-1", "uniprot_id": "FKBP6_DROME", "id": "Q9W1I9-1", "name": "Inactive peptidyl-prolyl cis-trans isomerase shutdown", "aln": "MEENFEPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKF--CVVYPKAVDLHLHGKDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPKRACIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKRISKYEEASRDIWARAFSLKNSKSDVRKTPAQLEKEAKEQDFNDKMEDLIRRFKNTSDQQVSFSRKSYSNAQFDATCKLAKEHNLKLTLSPIQEDVLTLSKPDVKFA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *. : * : **:.* *..: * : * * : *. .* * *:**** * ****. :* : ::: *:. .: *:*:.: *** * *.*::. :* ***** * *:: .**::*::*: .::. : *:. *::::* * *. : .*: .: .*: .* . ::**: *. :*:. :. * .* : * :.* *:::* : : . : * :.: ..****: *:* * **: **: ::** :** *::*.:*: .: . .* : .::: * *: .. * . . ", "identical_positions": 85, "similar_positions": 115, "identity": "18.6%" }, { "cls_id": "homologset.agr.FB:FBgn0003410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IUQ4-1", "uniprot_id": "SIAH1_HUMAN", "id": "Q8IUQ4-1", "name": "E3 ubiquitin-protein ligase SIAH1", "aln": "MSR-------------------------------QTATALPTGTSKCPPSQRVPALTGTTAS-------------------NNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61092-1", "uniprot_id": "SIA1A_MOUSE", "id": "P61092-1", "name": "E3 ubiquitin-protein ligase SIAH1A", "aln": "MSR-------------------------------QTATALPTGTSKCPPSQRVPALTGTTAS-------------------NNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920M9-1", "uniprot_id": "SIAH1_RAT", "id": "Q920M9-1", "name": "E3 ubiquitin-protein ligase SIAH1", "aln": "MSR-------------------------------QTATALPTGTSKCPPSQRVPALTGTTAS-------------------NNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZVG6-1", "uniprot_id": "SIAH1_DANRE", "id": "Q7ZVG6-1", "name": "E3 ubiquitin-protein ligase Siah1", "aln": "MSR-------------------------------QTATALPTGTSKCPPSQRVPTLSGTTAS-------------------NSDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLAMEKVANSVLFPCKYASSGCEVTLPHTDKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLLHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06985-1", "uniprot_id": "SIA1B_MOUSE", "id": "Q06985-1", "name": "E3 ubiquitin-protein ligase SIAH1B", "aln": "MSR-------------------------------QAATALSTGTSKCPPSQRVPALTDTTAS-------------------NNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLG-SIRNLAVEKVANSVLFPCKYSASGCEITLPHTKKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4T2-1", "uniprot_id": "SIAH2_RAT", "id": "Q8R4T2-1", "name": "E3 ubiquitin-protein ligase SIAH2", "aln": "MSRPSSTGPSANKPCSKQPPPPQTPHAPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGAGGGAGPVSP----------QHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06986-1", "uniprot_id": "SIAH2_MOUSE", "id": "Q06986-1", "name": "E3 ubiquitin-protein ligase SIAH2", "aln": "MSRPSSTGPSANKPCSKQPPPPQTPHAPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGAGGGADPVSP----------QHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43255-1", "uniprot_id": "SIAH2_HUMAN", "id": "O43255-1", "name": "E3 ubiquitin-protein ligase SIAH2", "aln": "MSRPSSTGPSANKPCSKQPPP-QPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSP----------QHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYL3-1", "uniprot_id": "SIAH2_DANRE", "id": "Q7SYL3-1", "name": "E3 ubiquitin-protein ligase Siah2", "aln": "MSRPSSAGGAAGGLGAGKAGG--SKHGGSGGTTASAAAAAAAAAAAAAAAAAAAGVSGSVAGSGTVPAAAVALPVAALPGQSPELTALFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGPLTPSIRNLAMEKVASTLPFPCKYSSAGCLLSLHHSEKPEHEEVCEFRPYTCPCPGASCKWQGSLEEVMPHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTSIAHLFADNGNLGINVTISMC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21461-1", "uniprot_id": "SINA_DROME", "id": "P21461-1", "name": "E3 ubiquitin-protein ligase sina", "aln": "MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAG------------------MSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLA-NIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. :* .:. .. . . . .. :*::******************.:***** .** **:*******.* .*****:****. : ****:: ** :* ::.*.:**: ** *** ************.*: ** **: ***********************************.************:********* ***:**:****.*******:******** *****:*:*:** *********:**:***:*********** ", "identical_positions": 194, "similar_positions": 48, "identity": "57.91%" }, { "cls_id": "homologset.agr.FB:FBgn0003415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6JPI3-1", "uniprot_id": "MD13L_MOUSE", "id": "Q6JPI3-1", "name": "Mediator of RNA polymerase II transcription subunit 13-like", "aln": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDV---------------------------KPDCKELWIFWWGDEPNLVGVIHHELQVVEE------GLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKS-EHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHLHMAQSS------------------------------------------------PAPFQVLVSPYGLNGTLTGHAYKMSDPAARKLIEEWHCFYPMVLRKREEP-------------------REE-AELGYDDDFPVAVEVIVGGVRMVYPSAFVLVSQNDIP-VPQS-----GHGTVA--QQGLGSVKDPSNCGMPLTPPTSPEQVVIGESGGVQSAASHLGSQDGGMSTMHSPK------RSRKTPPKLHSHMVRRVWRECILSRAQSKR--SQMSTPTRE--------------------------------EEAAHSPAAWDFVDPTQRVSCSCSRHKLLKRCAVGPSRPPAISQPGFSAGLPSSSSLPPPASSKHKTTERQEKGDKLQKRPLVPFHHRPSVAE------ELC-VEQDAPGQKLGLAGIDASLEVSNTRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQEAESLD----------PPSVPVNPALYG----NGLDLQQLSTIEDRTVLVGQRLPLMAEASETALYSGLRPSYTE-SSDRWWQSFRLPSSEDAEFRPPELQGERFDTALDLNPESTALQRLLAQP------NKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDTLGEVN-DPYTFEDGDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDSAAGRAGSG----SLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPTVG-----------------TEERPPGKDGRAAGPYPPTVA---DLQRMFPTPPSLEQHP-AFSPV-MNYKDGVSSETVTALGMMESPVVSMVPTHLTEFRMEVEDG-----------------------------------LGSPKPEEIKDFSYVHKVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAASSIRDGYNNVPSVGSLADPDY--VNTPQMNTPVTLN-SAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRG-GGTASGQGSVKYDSTD----------------------------------QGSPASTPSTTRP-----------------------------------------------------------------------LNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMN------IKGADVGLYIPDSSKEDQYR-------------------------------------------------------------------------------CTCGFSAIVNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQSSGQSTLLPQVEGARKA----------------PEPPVSLLLLLQNQHTQPFASLSFLDYISSANRHAL------------PCVSWTYDRVQADNNDYWTECFNALEQGRQYVDN----------PTGGKVDEALVRSATVHCWPHSNVLDTSMLSS-------------------QDVVRMLLSLQPFLQDAIQKKRTGRTWEN----IQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEES-DNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPG-NAGSLPSNSGSGAPPAGSAFNPTS-------------SSSANPTTSSSSAS--SGPPGSSAASAPGITQMNTTSSSGFGGGVGGQNPSAGGSSTDRTPGNVACG-DTEPGQSCTQSSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAE-EDSSSGNFWLLSLMRCYTEMLDHLPEHMRSSFILQIVPCQYMLQTMK-DEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPS--PIQLYSPPFILAPIKDKQ------TEPGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPS---------RSRKSKVSARKVGLQKLWEWCLGIVQMTSLPWRVVIGRLG-RLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNED---GFSPNNDDMFVDLPFPDDMDN--DIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQ-TDELLPARTSQRA---PHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LZT8-1", "uniprot_id": "F1LZT8_RAT", "id": "F1LZT8-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDV---------------------------KPDCKELWIFWWGDEPNLVGVIHHELQVVEE------GLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYDKDEKPVNKS-EHLSCAFTFFLHGESNVCTSVEIAQHQPIYVINEEHLHMAQSS------------------------------------------------PAPFQVLVSPYGLNGTLTGHAYKMSDPAARKLIEEWQCFYPMVLRKKEEP-------------------REE-AELEYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIP-VPQSGTSAGGHVTIA--QQGLGSVKDPSNCGMPLTPPTSPEQVVIGESG-VQSAASHLGSHDGGMIATHSPK------RSKKIPPKLHSHMVHRVWKECILNRAQSKR--SQMSAPAGE--------------------------------EEPAHSPAAWDFVDPTQRVSCSCSRHKLLKRCAVGPSRPPTLSQPGFSAGPPPPSSLPPPASSKHKTTERQEKGDKLQKRPLVPFHHRPSVAE------ELC-MEQDAPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQMDLNPMDSPHSPISPLPPTLSPQPRGQETESLD----------PPSVPVNPALYG----NGLDLQQLSALEDRTVLVGQRLPLMAEASETALYSGLRPSYTE-SSDRWWQSFRLPPSEDAEFRPPELQGEGFHTVLDVSPESTALQRLLAQP------NKRFKIWQDEQPQVQPLPFLDPSPLSQQPGDTLGEVN-DPYTFEDGDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSG----SLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPTVG-----------------TEERPPGKDGRAAGPYPPTVA---DLQRMFPTPPSLEQHP-AFSPV-MNYKDGVSSETVTALGMLESPVVSMVPTHLTEFRMEVEDG-----------------------------------LGSPKPEDIKDFSYVHRVPQFQPFVGSSMFAPLKTLPSHCLLPLKTPDACLFRPSWAVPPKMEQLPMPPAASSIRDGYNNVPSVGSLADADY--LNTPQMNTPVTLN-SAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRG-GGTASGQGSVKYDSTD----------------------------------QGSPASTPSTTRP-----------------------------------------------------------------------LNSVEPATMQPIPEAHSLYVTLILSDSVMNVFKDRNFDSCCICACNMN------VKGADVGLYIPDSSKEDQYR-------------------------------------------------------------------------------CTCGFSAIVNRRLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQTSCQSTLLPQVEGARKA----------------PEPPVSLLLLLQNQHTQPFASLSFLDYISSSSRHAL------------PCVSWTYDRVQADNNDYWTECVNALEQGRQYVDN----------PTGGKVDEALVRSATVHCWPHSNVLDTSMLSS-------------------QDVVRMLLSLQPFLQDAIQKKRTGRTWEN----IQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKEFLTISPFSLPFWERLLLEPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTEELVSEWFNQPWSSEES-DNHSRLKLYAQVCRHHLAPYLATLQLDSGLLMPPKHQSPPAEAQGQATPG-NAG--SSSSGSGAPPAGSAFNPTS-------------SSSA---ASSSSSC--SGPPGSSATSAPGITQMSTTSSSGFSGGVGGQNPSAGGSSTDGTPGNVACG-DAEHAQSCAQPSQDGQDSVTERERIGIPTEPDSADSHAYPPAVVIYMVDPFTYTAE-EDSSSGNFWLLSLMRCYTEMLDHIPEHMRSSFILQIVPCQYMLQTVK-DEHVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPS--PIQLYSPPFILAPIKDKQ------TEPGEAFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPSRTLPVPLSVRSRKSKVSARKIGLQKLWEWCLGIVQMTSLPWRVVIGRLG-RLGHGELKDWSILLGECSLQTISKQLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNED---GFSPNNDDMFVDLPFPDDMDN--DIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQARNQCPLFLKASLHHHISVAQ-TDELLPVRNSQRA---PHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71F56-1", "uniprot_id": "MD13L_HUMAN", "id": "Q71F56-1", "name": "Mediator of RNA polymerase II transcription subunit 13-like", "aln": "MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDV---------------------------KPDCKELWIFWWGDEPNLVGVIHHELQVVEE------GLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYEKDEKPVNKS-EHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHIHMAQSS------------------------------------------------PAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQYFYPMVLKKKEES-------------------KEE-DELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIP-VPQSVASAGGHIAVG--QQGLGSVKDPSNCGMPLTPPTSPEQAILGESGGMQSAASHLVSQDGGMITMHSPK------RSGKIPPKLHNHMVHRVWKECILNRTQSKR--SQMSTPTLE--------------------------------EEPASNPATWDFVDPTQRVSCSCSRHKLLKRCAVGPNRPPTVSQPGFSAGPSSSSSLPPPASSKHKTAERQEKGDKLQKRPLIPFHHRPSVAE------ELC-MEQDTPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETESLD----------PPSVPVNPALYG----NGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYCGIRPSNPE-SSEKWWHSYRLPPSDDAEFRPPELQGERCDAKMEVNSESTALQRLLAQP------NKRFKIWQDKQPQLQPLHFLDPLPLSQQPGDSLGEVN-DPYTFEDGDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDNAAGRAGSS----SLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPAVG-----------------TEDRPLGKDGRAAVPYPPTVA---DLQRMFPTPPSLEQHP-AFSPV-MNYKDGISSETVTALGMMESPMVSMVSTQLTEFKMEVEDG-----------------------------------LGSPKPEEIKDFSYVHKVPSFQPFVGSSMFAPLKMLPSHCLLPLKIPDACLFRPSWAIPPKIEQLPMPPAATFIRDGYNNVPSVGSLADPDY--LNTPQMNTPVTLN-SAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRG-GGTASGQGSVKYDSTD----------------------------------QGSPASTPSTTRP-----------------------------------------------------------------------LNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICACNMN------IKGADVGLYIPDSSNEDQYR-------------------------------------------------------------------------------CTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQS----TFLPQVEGTKKP----------------QEPPISLLLLLQNQHTQPFASLNFLDYISSNNRQTL------------PCVSWSYDRVQADNNDYWTECFNALEQGRQYVDN----------PTGGKVDEALVRSATVHSWPHSNVLDISMLSS-------------------QDVVRMLLSLQPFLQDAIQKKRTGRTWEN----IQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKDFLTISPFSLPFWERLLLDPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTDELVSEWFNQPWSGEEN-DNHSRLKLYAQVCRHHLAPYLATLQLDSSLLIPPKYQTPPAAAQGQATPG-NAG-PLAPNGSAAPPAGSAFNPTS-------------NSSSTNPAASSSASGSSVPPVSSSASAPGISQISTTSSSGFSGSVGGQNPSTGGISADRTQGNIGCGGDTDPGQSSSQPSQDGQESVTERERIGIPTEPDSADSHAHPPAVVIYMVDPFTYAAE-EDSTSGNFWLLSLMRCYTEMLDNLPEHMRNSFILQIVPCQYMLQTMK-DEQVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPS--PIQLYSPPFILAPIKDKQ------TELGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIALPN---------RSRRSKVSARKIGLQKLWEWCIGIVQMTSLPWRVVIGRLG-RLGHGELKDWSILLGECSLQTISKKLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNED---GFSPNNDDMFVDLPFPDDMDN--DIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQAQNQCPLFLKASLHHHISVAQ-TDELLPARNSQRV---PHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SWW4-1", "uniprot_id": "MED13_MOUSE", "id": "Q5SWW4-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "--MSSSFVSNGASLEDCHCNLFCLADLTGIKWKRYVWQGP-TSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQ---------------------------RPGRRELWIFWWGKDPNFADLIHHDLSEEED------GVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQS------------------------------------------------NSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCGLKEMS-------------------EEKQDDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIP-APSSVGASHCSASCLGIHQVPASTRDPAMSSVTLTPPTSPEEVQTVDPQSAQKWVKFS-SVSDGFSTDSTSH------HGGKIPRKLANHVVDRVWQECNMNRLQNKRKYSATSSGLCE--------------------------------EETADKIGCWDFVEATQRTSCSCLRHKSLKTRNTG------------QQGQAPSLGQQQQVLPKHKTNEKQDKSEKPQKRPLTPFHHRVSVSD------EIG-MDTDSASQRLVISAADSQVRFSNIRTNDVA-------KTPQMHG--TELANS---PQPPPLSPHPCDVVDEGVT---------KTPSTPQSQHFYQMPTPDPLVPTKP-MEDRIDSLSQSFPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYKVPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELM------VQCKKPLKVSDEIVQQYQIK-NQYLSAIASDTEQEPKIDPYAFVEGDEEFIFTD-KKDRQNSEREAGKKHKVEDGT--------SAVTVLSHEEDAMSLFSPS-KQDAPRPTNHARPPST----SLIYDSDLAVSYTDLDNLFN-SDEDELT------PGSKKSASG-----------------SDDKASSKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGSVDTAPGGTVLEGNSSSVG----TQFRIEVEEG-----------------------------------FCSPKPSEIKDFSYVYKPENCQVLVGCSMFAPLKTLPSHCLPPIKLPEECVYRQSWTVG-KLDLLPSGPSMPFIKEGD------GSNLDQDYGPAYTPQTHASFGMPPSSAPPSNGGAGILPSPSTPRF--PTPRTPRTPRTPRGAGGPASAQGSVKYENSD----------------------------------LYSPASTPSTCRP-----------------------------------------------------------------------LNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMN------IKGADVGVYIPDPTQEAQYR-------------------------------------------------------------------------------CTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRAS---SVENVNGGLKES----------------EKVPDELILLLQDQCTNLFS------PFGAADQDPF------------PKVGISSNWVRVEERDCCSDCCLALEHGRQFMDN----------MSGGKVDEALVRSSCLHPWAKQN--DASVQCS-------------------QDILRMLLSLQPVLQDAIQKKRTVRPWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCRLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNN--EAFSKLKLYAQVCRYDLGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGVPISTSVATANSTLTTTSSSSSSS--LSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSGQLGGQQSSSLQAAGIS--GESASLPTQPHPDVSESTMDRDKVGIPTDGD-SHAITYPPAIVVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPE--CIRLYTPPFILAPVKDKQ------TELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPN---------RARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLG-RIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMG-IFDLLDTGDDLDPDIINILPASPTASPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQ-SDELLHSKHS-------HPLDSNQTSDVLRFVLEQYNALSWLTCDPAVQDRRSCLPVHFVVLNQLYNFIMNML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LXU0-1", "uniprot_id": "F1LXU0_RAT", "id": "F1LXU0-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "--MSSSFVSNGASLEDCHCNLFCLADLTGIKWKRYVWQGP-TSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQ---------------------------RPGRRELWIFWWGKDPNFADLIHHDLSEEED------GVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQS------------------------------------------------NSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCGLKEMS-------------------EEKQEDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIP-TPSSVGSSHCSASCLGIHQVPASTRDPAMSSVTLTPPTSPEEVQSVDPQSAQKWVKFS-SVSDGFSTDSTSH------HGGKIPRKLANHVVDRVWQECNMNRLQNKRKYSATSSGLCE--------------------------------EETADKIGSWDFVEATQRTSCSCLRHKSLKTRNTG------------QQGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSISD------DIG-MDTDSASQRLVISAADSQVRFTNIRTNDVA-------KTPQMHG--TELANS---PQPPPLSPHPCDVVDEGVT---------KTPSTPQSQHFYQMPTPDPLVPTKP-MEDRIDSLSQSFPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYKVPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELM------VQCKKPLKVSDEIVQQYQIK-NQYLSAIASDTEQEPKIDPYAFVEGDEEFIFTD-KKDRQNSEREAGKKHKVEDGT--------SAVTVLSHEEDAMSLFSPS-KQDAPRPANHARPPST----SLIYDSDLAVSYTDLDNLFN-SDEDELT------PGSKKSASG-----------------SDDKASSKESKTGSLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGSMDPTPGGTVLEGSSSSVG----TQFRIEVEEG-----------------------------------FCSPKPSEIKDFSYVYKPENCQVLVGCSMFAPLKTLPSHCLPPIKLPEECVYRQSWTVG-KLDLLPSGPSMPFIKEGD------GSNLDQDYGPAYTPQIHTSFGMPPSSAPPSNGGAGILPSPSTPRF--PTPRTPRTPRTPRGAGGPASAQGSVKYENSD----------------------------------LYSPASTPSTCRP-----------------------------------------------------------------------LNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMN------IKGADVGVYIPDPTQEAQYR-------------------------------------------------------------------------------CTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRAS---SVENVNGSLKES----------------EKVPDELILLLQDQCTNLFS------PFGAADHDPF------------PKAGISSNWVRVEERDCCSDCCLALEHGRQFMDN----------MSGGKVDEALVRSSCLHPWAKQN--DASVQCS-------------------QDILRMLLSLQPVLQDAIQKKRTVRPWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCRLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNN--EAFSKLKLYAQVCRYDLGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTLTPGVAISTSVATANSTLTTTSSSSSSS--MSSGVSSNKLPSFPPFGSMNTSGTGSMSAQGSTVQSGQLGGQQSSSLQAAGIS--GESASLPTQPHPDVSESTMDRDKVGIPTDGD-SHAITYPPAIVVYIIDPFTYENKDESTSSSNVWTLGLLRCFLEMLQTLPPHIKSTVSVQIVPCQYLLQPVKHDDRQIYSQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPE--CIRLYTPPFILAPVKDKQ------TELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPN---------RARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLG-RIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMG-IFDLLDTGDDLDPDIINILPASPTTSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQ-SDELLHSKHS-------HPLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHV7-1", "uniprot_id": "MED13_HUMAN", "id": "Q9UHV7-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "--MSASFVPNGASLEDCHCNLFCLADLTGIKWKKYVWQGP-TSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQ---------------------------RPGRRELWIFWWGEDPSFADLIHHDLSEEED------GVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQS------------------------------------------------NSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMS-------------------EEKQEDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIP-TPSPVGSTHCSSSCLGVHQVPASTRDPAMSSVTLTPPTSPEEVQTVDPQSVQKWVKFS-SVSDGFNSDSTSH------HGGKIPRKLANHVVDRVWQECNMNRAQNKRKYSASSGGLCE--------------------------------EATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAG------------QQGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSD------DVG-MDADSASQRLVISAPDSQVRFSNIRTNDVA-------KTPQMHG--TEMANS---PQPPPLSPHPCDVVDEGVT---------KTPSTPQSQHFYQMPTPDPLVPSKP-MEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYKFPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELM------VQCKKPLKVSDELVQQYQIK-NQCLSAIASDAEQEPKIDPYAFVEGDEEFLFPD-KKDRQNSEREAGKKHKVEDGT--------SSVTVLSHEEDAMSLFSPSIKQDAPRPTSHARPPST----SLIYDSDLAVSYTDLDNLFN-SDEDELT------PGSKKSANG-----------------SDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGSMDTTPGGTVLEGNSSSIG----AQFKIEVDEG-----------------------------------FCSPKPSEIKDFSYVYKPENCQILVGCSMFAPLKTLPSQYLPPIKLPEECIYRQSWTVG-KLELLSSGPSMPFIKEGD------GSNMDQEYGTAYTPQTHTSFGMPPSSAPPSNSGAGILPSPSTPRF--PTPRTPRTPRTPRGAGGPASAQGSVKYENSD----------------------------------LYSPASTPSTCRP-----------------------------------------------------------------------LNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMN------IKGADVGVYIPDPTQEAQYR-------------------------------------------------------------------------------CTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRAT---SAEHVNGGLKES----------------EKLSDDLILLLQDQCTNLFS------PFGAADQDPF------------PKSGVISNWVRVEERDCCNDCYLALEHGRQFMDN----------MSGGKVDEALVKSSCLHPWSKRN--DVSMQCS-------------------QDILRMLLSLQPVLQDAIQKKRTVRPWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCRLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNN--EAFSKLKLYAQVCRYDLGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSGVAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQSGQLGGQQTSALQTAGIS--GESSSLPTQPHPDVSESTMDRDKVGIPTDGD-SHAVTYPPAIVVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVKHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPE--CIRLYAPPFILAPVKDKQ------TELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPN---------RARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLG-RIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMG-IFDLLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQ-SDELLHSKHS-------HPLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2VCZ5-1", "uniprot_id": "MD13L_DANRE", "id": "A2VCZ5-1", "name": "Mediator of RNA polymerase II transcription subunit 13-like", "aln": "--MSSCFVPNGASLEDCHSNLFCLADLTGIKWKCFVWQGP-TSSPILFPVTEEDPILCSFSRCLKADVLSVWRRHQ---------------------------TPGRRELWIFWWGDDPNFAELVHHDLSCNED------GSWESGLTYECRTLLFKAIHNLLERCLMNRSFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFVHGDSNVCTSVEINQHQPVYLLSEEHLTLAQQS------------------------------------------------SSSVQVILSPYGLSGTLTGQSFKLSDPPTQKLIEEWKQFYPIGPNTKEVT-------------------DDKMDDLDWEDDSLAAVEVVVAGVRMVYPASLVLVAQSDIP-LVATVSSSSSSGSYAGAPHNQLVHGDTGISSVTLTPPTSPEEAQAVS-QPAQKWVKLS-AMSGVFSVDSSSH------HGGKIPRRLASQMVERVWQECNINRAQNKRKFSTMSNGVCE--------------------------------EET-DKASVWDFVESSQRSQCSCSRLKNQKQRACS------------TPGHPPSAGQPPQPSTKHKMAEKLEKGDKQQKRPLTPFHHRSSLCE------EQPSLEQGESVHRLCLQGHE-DSRYPSLHHADVTS-----SKTPMLHSSADEMAGS---PQPPPLSPHPCERMEEPADGM-------KSSSSPLHQHFYPPSSEPCLEPQKPPDESTLDPLPLPCPPPYPETLEATIYVGSAINPNEDTTHNPWKYFRVPGGRNSDFHTPHLPVVAHFEDGNRTGGQDGIVSITEMM------SSSKRPLKVSEELVKMYEHKKNQYLSSAVCDEDPEQESDPYAFEEGDEEFNFSD-KDKKSGPEREAGKKAKREDGS--------SSS------------------DDAQGSGGSKPLPTT----SLIHETDLVVSINDLDNLFN-SDEDDLTQ-----PGSRRAAGG-----------------AEEKFGGKEPKPAAPDPLPCC--ADLHQMFPTPPSLDQ---GYSPINMGN-----TESAAGLSLLDG---AMS----GNFKMEVEEG-----------------------------------FCSPKPSEIKDFSYVFKPESCQALIGCSLYAPLKTLPSQCLLPVKLPEECVYRPSWTVG-KLGMLQPMAAMTFLNKDSN-IPSVGSVVEQEQ--SCTPQTHNTFMS--NSAPPSNSGAGILPSPATPRI--SAP-TPRTPRTPRTPRGPASVQGSLKYENSD----------------------------------LNSPASTPSTCRP-----------------------------------------------------------------------LSSVEPATVPSIPEAHSLYVTLILSESVMNLFKDCNFDSCCICVCNMN------ITGADVGIYISDPNMDSQYSSMDP---------------------------------------------------------------------------CSCGFSAVMNRRYGNGAGLFLEDELDIMGRGSDAAREIEKHFEAVRAA---SLK---RGTVLE----------------EQVPDDLMLLLQDLCTNPFS------PIIRPD----------------LLGTVIKSPIRLEERDYYSDCYMALEHGRQFMDN----------MSGGKVDETLVKSSSLHHWAKRNAFDMSMLFS-------------------QDVLRMLLSLQPVLQDTIQKKRSVRSWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTLLVGYEYDYVVLSPFALPYWEKLLLDPYSSQRDVGYMVVCPDNEALLNGAKTFFRDLTAVYESCRLGQHRPIAKSHADGIVTVSDAGSKALTDQTLIDWLPKTINSSSSSEALNKLKLYAHVCRHDLASCLASQSLDGSLLTQRNPASSSQTSSSSSPVTTAQN--VTPTTNSNSNTNTNTTPTS---------------TSTSSSSSSCPQGVGNMPSSKPNTIPPFG-----AQGLQSSQQS-------GGQSAGTLGDATSA--TSQPQVPSEP----AESTMEREKVGVPTDGD-SHAVTYPPAIVIYIVNPFSYEENCQGS-SSSVWTIALLRCYLEMLQLLPPHIRNAVYVQIIPSQYLLQPVWSEERHIYAQHLKSLAFSVYTQCRRRLPTSTNVKTLTGFGPGLAIDTALQSKERPQ--CLHLYAPPFVLAPVKDKQ------TELGETFGEAAQKYNVLFVAYCLSHDQRWLLASCTDQYGELLETCVISIDVPN---------RARRKKGSARRQGLQKLWEWCLDLVQMTSLPWRIVIGRLG-RIGHGELRDWSILLSRRNLQSLGRRLKEMCRMCGISAADSPSILSTCLVAMEPQASFVIMPDSVSTGSVFGRSTTLNMQTSQLNTPQDTSCTHILVFPTSAGLQ-------------AFSDVTDGMGGMDGILDLFAENDLVDPDLINIIPNSPTTSPVHSPGSHYHHGGDGSKGQGTDR---MESHDESPNILQQPMALGYFVSTAKAGPLPDWFWSSCPQAKNQCPLFLKASLHLNVSSVQ-SDELLHSKHS-------HPLDSSHTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPVHFVVLNQMYNFIMNML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTX8-1", "uniprot_id": "MED13_DROME", "id": "Q7KTX8-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "-MTHQNHQTNGASLEDCHTNFYALTDLCGIKWRKFVNGER----PNASSDPLADPILRSYSRCIQADMLCVWRRVQSTKTDHADPNALTFEMTTSTKVHPPLSLAAAKELWIFWYGEEPDLSELVDAELLRVAANQALWNGTWKGALTYECRSLLFKALHNLMERFVLTKDIVRFGKWFVQPCTSSDRLFGRSSQHLSFSFTFFVHGDT-VCASIDLREHPAVRPLTKEHLTEAAAAFAAASSPPGSNGSAASAGGAVPNPGQDPNGASMDGLDGGEGAAKAAPPPHARKVMLAPFGIAGILTGNSYKASDPIAEKILEDWASFFPLCNKDNTDVPPVVEVVSGGHKMYHPTNYVLVTDLDDMEHMEFVEMQKMQSSVAGAAAESAVLASLSCPPGAASAPSSMGAAPSATAVPLGPASLNAPALAGAGVGATASSAAKEISRKAAPQAVSALERLAFQPYYDQRPTSGFTFNTNNTHIPASAAVEMPERTWQDCVMNTLHVDAAAAAAAVASSTPASGTGSLSADGDENEQNKPPQDSKQLVQQQIQQQQQRQKLWNFVDPMQKAPCICTKHLGNTPHGTP------------HGGASTYSRNSLGGDSSMPVASVESPATPAPSPHPNSAHSQPTSVP------PAEQLLNMSPHAPTSVSNLQQPPTPIDHLLDKNTPAPTPTDQHDSKSITASPYVHQTPSVEPPSYTDHAAGGGPAGGQGLGTGPGSVPAQQPATPTAATSAGGAGSGGPSNAIGANAVGTISVKKLEMQQQTPSAAMAIKQEPGAQGRGVGGVTSTTEALNNFKRLYNPPKLTLKDPDSFYDEEWLKEVIYDFQYQEYWDYSTVKRPKMEKQRRPRYAKNLYEGQNHVKPVMPSPGSVYGSQLLSLDESASQAGGRGGGGQAAGSSGGGLVGIANSTASGSDVEADGSSFFQGLNIKTEPGLHSPSCKETSKSSGGNSSGGGSGSGGNLFTAEGLNPSLNDLEQLFETSSNDECSSVQIHTPPDSNNPSNGGCSAVTNTIEDLKRSTAVASAAVAAAAAAAASGAGNIQAEDLTKMFPTPPSHEQQHPNSSPCQTDVVMTDLSVDTTTTIITSSITTTCNTTITSSINTTTTACSNPSNSIMLAAAQAPVTVVAIQTVSKMVKQEYNLELGSPMEEPINDWDYVYRPPQQEKFVGSTRYAPLTNLPSQTQPPLTLPTGCFYQPTWSSHKSRAATLAKAAAAQQQQHQKHQALQQRIQLHQQKLQQLQLQNQQQQQAAAAAAAAASGGVGHQKHQHQHLHDLLSAAPRTPLTPSTVPQPLSSGGSQYLLNQLNCPQAPPGASMQQLMHRAGMSPISPGPGMGPYAARSSPMSRATPTHPPPPYPYDLAVASPATSTSSYLNRPLHSQEHPHMHGLGGGATGVVGHGTGGGGHMGMVAYTGDAGIVSGGTAMAAGSSSLLQELPEVNSVLVNILLYDTALNVFRDHNFDSSSVCVCNADTQKIGNIRGADSGVYVPLPGVSFNPFPSGAGGALAGQRMLNGPSSAGFGGMRMISAFGGSPASASMPGAGSGHGHGPNGGSNSSSCTPPSSNPHITGYVDDDPVECTCGFSAVVNRRLSHRAGLFYEDEVEITGIADDPGRNKQPTLLSIIQSLSRKNQNKQGPGETSSALDKIGAGGLPNGQLEQLGHAVFDLLLDQCSIIQTSSSSVHRALQSHRRRMSRQRRIFGNNGAPTASLASIANVLEFMDAHDVISLALEQSRLAFENQRMDNMMDFHGNGSSSSHQQQQLTAFHAPPPALRHKLAGIGAGRLTVHKWPYLPVGFTRSNKEIVRTMNAIQPMLQNAFHCKSRGGSGSKDASSYNTVSGPLTWRQFHRLAGRASG----QCEPQPIPSVVVGYEKDWISVAPHSIHYWDKFLLEPYSYARDVVYVVVCPDNEHVVNCTRSYFRELSSTYEMCKLGKHTPIR--GWDGFLQVGAARNNVPADRETTPLDDWLRTLEHA-ALAEQIRRYAVAFIHQLAPYLSRVPNDKTLLNPPDGSGNSHSKGGSSCSSNSSSVSGLPGGDLPTDN-------------------------------------------------------IKLEPGTEPQVQPMETNEIKQEPGVGKGGTAAG------------------ETKPTLILGDPLGMGETLEDINPSAIVLYVVNPFTFASD--SCELERLALIALLRCYAELLKAVPDSVRSQMNIQIISLESVMELGPCGNRKRFSDEIRCLALNIFSQCRRHLVHAQSVKSLTGFGTAANMEAFLKTKDEPNRRAYKMYTAPFVLAPMHERNDKTDFSRSAGSMHGQNEHRYSVMYCNYCLSEDQAWLLATATDERGEMLEKICINIDVPN---------RARRRKAPARYVALKKLMDFIMGIISQTSQMWRLVIGRIG-RIGHSELKSWSFLLSKQQLQKASKQFKDMCKQCTLMYP--PTILSACLVTLEPDAKLRVMPDQFTPDERFSQISMQNP----LATPQDVTCTHILVFPTSAVCAPFTRQFQNEP------QVDDDFLTFEEEGNEDFSDADIGDLFWDTHMDR--VSNHGSPGRMDDNRSWQSAGGNNFKCTPPQEVEEVGSLNQQPISVGYMVSTAPTGRMPAWFWSACPHLEDVCPVFLKTALHLHVPSIQSADDILNSTNAHQSG-NDHPLDSNLTADVLRFVLEGYNALSWLALDSNTHDRLSCLPINVQTLMDLYYLTAAIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38931-1", "uniprot_id": "SSN2_YEAST", "id": "P38931-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "----MSSDASTYRLEDVLSSFYRVEKIKKINYHQYISKAQ--------NDQWSIQMEFMLRKQDPKTLVALLSR----------------------------------DLWCFSINDDPVPTPPAIEHKPVSPDK----IGTFTADYSKPNLPPHYALFLKALRRKIYINLALGSHNKLIQFGNACISLSGVPNYLVQLEPHLFVNGDLTVSLCAKN---MGLVPMKEENLEESFLS--------------------------------------------------KHALYLAPSGIRMHLAPASKQGYLITPPKHTELLLTTLSVSHGINLQN---------------------------KKNLKWVAVVPDLGHLNGHTPTIASYLTP--------------------------------------------------------------------------------------------LLEAKKLVWPLHLIFAQPVADIENSTSGDPSE-----------------------------------------FHCLQDALDAIDDFIQLKQTAAYRTP----------------GSSGVLSSNIAGTNPLSSDGAYTEQFQHYKNNSISSQPASYHSVQETNKIS----------------------------------------------------------PKDFSPNFTGIDKLMLS-----------PSDQFAPAFLNTPNNNINENELFNDRKQTTVSNDLENSPLKTELEANGRSLEKVNNSVSKTGSVDTLHNKEGTLEQREQNENLPSDKSDSMVDKELFGEDEDEDLFGD------------------------SNKSNSTNESNKSISDEITEDMFEMSDEEENNNNKSINKNNKEMHTDLGKDIP---------------------------FFPSSEKPNIRTMSGTTKRLNG-------KRKYLDIPIDEMT-------------------------------------------------------------------------LPTSP-----------------------------------------------LYMDPG-----------------------------------APLPVETPRDRRKSVFAPLNFNPIIENNVDNKYKSGGKFSFSPLQKEEALNFDISMADLSSSEEEEDEEENG--------------------------------------SSDEDLKSLNVRDDMKPSDNISTNTNIHEPQYINYSSIPSLQDSIIKQENFN----------------------------------SVNDANITSNKEG-----------------------------------------------------------------------FNSIWKIPQNDIPQTESPLKTVDSSIQPIESNIKMTLEDNNVTSNPSE--------------FTPNMVN--------------------------------------------------------------------------------------SEISNLPKDKSGIPEFTPADPNLSFESSSSLPFLLRHMPLASIPDIFITPTPVVTISEKEQ---------------------DILDLIAEQVVTDYN------------------------------------------------ILGNLGIPKIAYRG------------VKDCQEGLITTTMLQLFSTFDR---------------------------------------------------------------LNGNDTISKFYNMK---------------QPYVFVKKHHELIKVKHDSQPFIKFLNFRPPNGIKNFKSLLLSS---SFKEDCLSFAPTLSQTYINQELGFCELLKLTNEDPPGLMYLKAFDKNKLLLLAAQIVSYCSNNKN-------------SIKNVPPILIILPLDNATLTELVDKANIFQVIKN-----------------------------------------------------------------------------------------------------------------------------------------------EVCAKMPNIELYLKVIPMDFIRN----------VLVTVDQYVNVAISIYNMLPPKS-------------------------------VKFTHIAHTLPEKVNFRTMQ----QQQMQQQQQQQQQQQ---------------------------NNSTGSSSIIYYDSYIHLAYSRSVDKEWVFAALSDSYGQGSMTKTWYVGNSR----------------GKFDDACNQIWNIALNLASKKFGKICLILTRLNGILPDDELMNWRRLSGRN--------------------------IHLAVVCVDDNSKISFIDEDKLYPS------------------------------------------------------------------------------------------FKPIYKDTRFGGRMDMTRLYDYEIRDIDQDIHGIVFQHPFPLAHSQHRCAIRSGALIKFKKCDGDTVWDKFAVNLLNCPHSDSTQLLETILEEFRNLAALNVWYGLSDGEDGHIPWHILAVKKMMNTLVHTRVKIANTSAATVHTATSSSIILSDK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *** .:: : .: *::: : : : :: : * :** * ..:* . * : : . : . : :.* : . : : ::: . . :. :*::*: *. . . : :.:*:: : : : :.* *: *: : : . * .: . .. . : . : . . . .* : : :. :: : . . . . : : * : : . . .. . . . .* . . : : : : * . :: **.* * . . *. . : :: . . . *: : : : . :. . . : * . . . . . .: . : : :*:..* .: :: . .::. : : : . . :* : : : . : ::.: . . : :: *: : * : . . .. : .: . :.* * :*:.: * ..: . : : : : : . : : * . ::. :::.. . : :: *: * .** : * : . . .: . * * * * : : *: : : : : :: : : : : : * .::: :: : :. . . . .. . :. *. * *: *::*: :* *: . : . . ::: : :.: . . ::: *:. : ..** .* * .. : .:* :: :..: .: : . . : : *:*:.:.: . . :. * . :: : * : :* : *.. ..: .:* : :. *. . *. .:: . .: ", "identical_positions": 73, "similar_positions": 338, "identity": "2.66%" }, { "cls_id": "homologset.agr.FB:FBgn0003416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10686-1", "uniprot_id": "PLCG1_RAT", "id": "P10686-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "--------------------------------------------------------------------------------MAGVGTPCANGCGPSAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLT--WLMEDTLQAATPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETN---TLRTGERPELCQVSLSEFQQFLLEYQGELWAVDRL--QVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSV------------------MYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPK-----------------EASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEAL--EKIGTAEPDYGALYEGRNPGFYVEANPMP--TFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAILEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPS-VAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWP--AKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62077-1", "uniprot_id": "PLCG1_MOUSE", "id": "Q62077-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "--------------------------------------------------------------------------------MAGVATPCANGCGPGAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLT--WLMEDTLQAATPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETN---ALRTGERPEHCQVSLSEFQQFLLEYQGELWAVDRL--QVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLRRKILIKHKKLAEGSAYEEVPTSV------------------MYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPK-----------------EASSSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEAL--EKIGTAEPDYGALYEGRNPGFYVEANPMP--TFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPS-VAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWP--AKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGISLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERSTSDGPSSATNLIEDPLHDKLWKCSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19174-1", "uniprot_id": "PLCG1_HUMAN", "id": "P19174-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "aln": "--------------------------------------------------------------------------------MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADK-----IEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLT--WLMEDTLQAPTPLQIERWLRKQFYSVD----------RNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEAS---TLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRL--QVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSM------------------MYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPK-----------------EVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSE-FDSLVDLISYYEKHPLYRKMKLRYPINEEAL--EKIGTAEPDYGALYEGRNPGFYVEANPMP--TFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMAS-VAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWP--AKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAP----RRTRVNGD---NRL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIH5-1", "uniprot_id": "PLCG2_MOUSE", "id": "Q8CIH5-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "------------------------------------------------------------------------------------MTTMVN---VDTLPEYEKSQIKRALELGTVMTVFNARKS-TPERRTVQMIMETRQVAWSKTADK-----IEGFLDIMEIKEIRPGKNSKDFERAK---AVRHKAECCFTILYGTQFVLSTLSLATDSKEDAVKWLSGLK--ILHQEAMSASTPTMIESWLRKQIYSVD----------QTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLN--KVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDMLLTKPTEASADQLPSPSQLREKIIIKHKKLGP---KGDVDVNV------------------EDKKDEHK---PQGELYMWDSIDQKWTRHYCAIADAKLSFGDDIEQA----VEEEPV-----------------QDTPPTELHFGEKWFHKKVES----RTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR-KREGTNSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELL--ERYN-MERDINSLYDVSR--MYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDN-PLGSLCKGILDLNTYNVVKAPQGKNQKAFVFILEPKK-QGDPPVEFATDRVEELFEWFQSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHL--ENPDFREIRSFVETKADSIV-RQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQR-KILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLR-----EKRVSNS----RFYS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24135-1", "uniprot_id": "PLCG2_RAT", "id": "P24135-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "------------------------------------------------------------------------------------MTTMVN---VDTLPEYEKSQIKRALELGTVMTVFSARKS-TPERRTVQMIMETRQVAWSKTADK-----IEGFLDIMEIKEIRPGKNSKDFERAK---AVRHKADCCFTIFYGTQFVLSTLSLATDSKEDAVKWLSGLK--ILHQEAMNASTPTMIESWLRKQIYSVD----------QTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLN--KVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGP---RGDVDVNV------------------EDKKDEHK---TQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQT----VEEDPV-----------------QDTPPTELHFGEKWFHKKVES----RTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIR-KREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELL--ERYN-MERDINSLYDVSR--MYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDN-PLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKK-QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHL--ENPDFREIRSFVETKADSIV-RQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQR-KILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFLVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLRLYQEKCNRRLR-----EKRVSNS----RFYS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16885-1", "uniprot_id": "PLCG2_HUMAN", "id": "P16885-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "aln": "------------------------------------------------------------------------------------MSTTVN---VDSLAEYEKSQIKRALELGTVMTVFSFRKS-TPERRTVQVIMETRQVAWSKTADK-----IEGFLDIMEIKEIRPGKNSKDFERAK---AVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLK--ILHQEAMNASTPTIIESWLRKQIYSVD----------QTRRNSISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHDFQRFLIHEQQEHWAQDLN--KVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGP---RGDVDVNM------------------EDKKDEHK---QQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQT----MEEEVP-----------------QDIPPTELHFGEKWFHKKVEK----RTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR-KREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELL--ERYN-MERDINSLYDVSR--MYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDN-PLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKQ-QGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNL--ENPDFREIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQR-KILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLR-----EKRVSNS----KFYS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXH3-1", "uniprot_id": "Q9VXH3_DROME", "id": "Q9VXH3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "aln": "-------------------------------------------------------------------------------------MSCFS--AMSAPLLGEMEQTIGMLERGTIVTKLYGKQR-RPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFADD-CQRFESSKCFVILHGNHFKLKSFSVVALSEIEADNWVRGLR--YMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKDFKLFLAGVSCKMTTGKFMEHFTEDVR-RKHDLKFDDFSRLYQKLLLPNG---FASVLSGSGVANFPYSE--DQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMD-MNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGG---RKEADDLLKKYKHFG---DGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIG-SFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMN-FESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEEN----VTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDS---TTEDYNSLNEE---GTDGR-TDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSW-----IFQEMSSFPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNNPLCDG-LSEVKVSIRLIAARHLFRGGK-SNNPQIVVELIGASFDTGVKYRTKVNENGFNPVWN---ESCEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIANVTAP-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRR---KFYEFKLINNNGQIIWKDGSKY---------LELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSE----KEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKP-----------PHSHLSFENFFQFLITEQHEQVDRQTA----WSYFIKYREPTQLTMGQ-----DGFTKFLKEQ------PYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENG-PVVCHG-FLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTR--TDKLPSPRELKHKILLKSKKTSE----------------------------------------ATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNS----------------------------------------------------SSATNSSSMQRIKRIGLKKHADIINDVSNISGIHGIKFRN-------------------FSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRR---------------------YLMR--------------------------------------------------------------------------------------------------------------------VYPHVLRYKSSNFNPIPFWKAGVQMVATN----WQTNDIG------------------------------------------------------------------------------------------QQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFE-----------------------------------------------NGSDPVTVKIRILSTQLLPR----------LNDTSPSRNNTNSFVKVEFHTDDEPTMPIS------------------------------------IDKGTRISATEASTKSSQGNGFNPIWD---AEVSITLKDTDLTFIKFMVIS-----EETQIASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: * : : :: . . : :. *: * : ::: .:::** *. : : * . . :.*:: *.:: : : .: : :: : . : . : : : :.: :: :.* : . :. :::. :. :.: :* : : * : :: :** * : : . : .: : : :* .: * : . **. *:*:******* *.*: . .* *.* : *: ****:*:* *:* :. * : ** *: * : *::.*:.:** :* :*:*:*:* :*. :*: : : :*:.: * : **** :*:.**::* ** * . :.. .: :: .: . :: : . : ::.: .: . : :.* . : * :. .: : * : :: .:.: * . . * * . : **:.. : :.* : .: . . * .* * : :. : . . :: :: : . . :.*: .. : .:*::. :*.: . .:: : * *: . **:.*:* : : :.::::::* * . : :* . :. :: *:* : * * .*: :.:*:: .: ", "identical_positions": 102, "similar_positions": 254, "identity": "7.04%" }, { "cls_id": "homologset.agr.FB:FBgn0003423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAR6-1", "uniprot_id": "F1MAR6_RAT", "id": "F1MAR6-1", "name": "Proline dehydrogenase", "aln": "--MGRDQGVIQGVASPMYLSFLSALTG-SAMALKRVF-LLRSVAPRVAALSTKPRA-----------------QEQPPANPEALRGCGAAEAVRP-------PVPA---------VDFTNTQEAYRSRRSWELARNLLVLRLCASPVLLAHHEQLFQVARKLLGQRMFERLMKMTFYGHFVAGEDQESIRPLIRHNKAFGVGFILDYGVEEDLSPEEAERKEMESCTSEAERDGSGANKREKQYQVHPAFGDRRDGVISARTYFYASEAKCDNYMENLLQCIEAS-------------GGASDGGFSAIKLTALGRPQFLLQFSDVLTRWRQFFHQMAAEQGQAGRPAVDTKLEVAVLQESIAKMGISSRAEIERWFTPETLGVSGTVDLLDWNSLIDSRTQLSRHLVVPNVQTGQLEPLLSRFTEEEEQQMKRMLQRMDVLAKRAREAGVRLMIDAEQSYFQPAISRLTLEMQRRFNVDKPFIFNTFQCYLKDAYDNVTIDMELSRREGWCFGAKLVRGAYMAQERARAVEIGYEDPINPTYEATNAMYHRCLNYVLEELKHS-------TKAEVMVASHNEDTVSFTLCRMKELG-LHPADGQVCFGQLLGMCDQISFPLG--QAGFPVYKYVPYGPVMEVLPYLSRRALENSSIMKGAQRERQLLWQELCRRLRTGSLFHHPA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU79-1", "uniprot_id": "PROD_MOUSE", "id": "Q9WU79-1", "name": "Proline dehydrogenase 1, mitochondrial", "aln": "------------------------------MALKRVF-LLRSVAPRVAALSTKPQA-----------------QEQPPASPEALRGCGAAKAVRP-------PVPA---------VDFTNTQEAYRSRRSWELVRNLLVLRLCASPVLLAHHEQLFQVARKLLGQRMFERLMKMTFYGHFVAGEDQESIRPLIRHNKAFGVGFILDYGVEEDLSPEEAERKEMESCTSEAERDGSGANKREKQYQVHPAFGDRRDGVISARTYFYANEAKCDNYMENLLQCIKAS-------------GGASDGGFSAIKLTALGRPQFLLQFSDVLTRWRRFFHQMAAEQGQAGRAAVDTKLEVAVLQDSIAKMGIASRAEIEGWFTPETLGVSGTVDLLDWNSLIDSRTRLSRHLVVPNVQTGQLEPLLSRFTEEEEQQMKRMLQRMDVLAKKAKEAGVRLMIDAEQSYFQPAISRLTLEMQRRFNVDKPFIFNTFQCYLKDAYDNVTLDMELARREGWCFGAKLVRGAYMAQERVRAAEIGYEDPINPTYEATNAMYHRCLNYVLEELKHS-------TKAEVMVASHNEDTVHFTLCRMKEIG-LHPADGQVCFGQLLGMCDQISFPLG--QAGFPVYKYVPYGPVMEVLPYLSRRALENSSIMKGAQRERQLLWQELRRRLRTGSLFHHPA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43272-4", "uniprot_id": "PROD_HUMAN", "id": "O43272-4", "name": "Proline dehydrogenase 1, mitochondrial", "aln": "------------------------------MALRRALPALRPCIPRFVPLSTAPAS-----------------REQPAAGPAAVPGGGSATAVRP-------PVPA---------VDFGNAQEAYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAGEDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQYQAHWAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEAS-------------GRVSDDGFIAIKLTALGRPQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRMLQRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAYDNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEELKHN-------AKAKVMVASHNEDTVRFALRRMEELG-LHPADHRVYFGQLLGMCDQISFPLG--QAGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTGNLFHRPA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04499-1", "uniprot_id": "PROD_DROME", "id": "Q04499-1", "name": "Proline dehydrogenase 1, mitochondrial", "aln": "MALLRSLSAQRTAISLVYGRNSSKSSNSVAVAACRSFHQRGSGSTSIAGEGAASESTRGVNGARFLHSGDRPLQASTLVQPEVVSSETVKRSMKQESSQEKNPSPAGSPQRDPLDVSFNDPIAAFKSKTTGELIRAYLVYMICSSEKLVEHNMTLMKLARNLLGQKLFVLLMKSSFYGHFVAGENRHTIVPALERLRSFGVKPILDYSVEEDITQEEAEKREVESSVSSAGDKKEEGSMP--QYHVDKSFADRRYKVSSARTYFYLNEATCERNMEIFIKCLEAVSDDDRKAPRAVATGATFGTGITAIKLTALGRPQLLLQLSEVIMRTRKYMEDMVGGQG----NVLTHHKTIKDLEKYYATLGDNK--DVKEFLNNVTSDKEGILHLFPWSGIVDEDSQLSDTFRVPDPQTGQMRRLISQIPPKEEEMFRNMIRRLNTIVKAAADLDVRIMVDAEQTYFQPAISRITLEMMRKYNKDKAIVFNTYQCYLRETFREVNTDLEQAKRQNFYFGAKLVRGAYMDQERDRAKSLGYPDPVNPTFEATTDMYHRTLSECLRRIKLMKDCDDDARKIGIMVASHNEDTVRFAIQQMKEIG-ISPEDKVICFGQLLGMCDYITFPLG--QAGYSAYKYIPYGPVEEVLPYLSRRAQENKGVLKKIKKEKRLLLSEIRRRLMRGQLFYKPKGNYVPI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09368-1", "uniprot_id": "PUT1_YEAST", "id": "P09368-1", "name": "Proline dehydrogenase, mitochondrial", "aln": "-----------------------------MIASKSSLLVTKSRIPSLCFPLIKRSY-----------------VSKTPTHSNTAANLMVETPAAN--------------------ANGNSVMAPPNSINFLQTLPKKELFQLGFIG--IATLNSFFLNTIIKLFPYIPIPVIKFFVSSLYCGGENFKEVIECGKRLQKRGISNMMLS-----LTIENSEGTKSLSSTPVDQIVKETIS------------------------------SVHNILLPNIIGQLESK------------------------PINDIAPGYIALKPSALVDNPHEVLYNFS-----------------------------------------------NPAYKAQRDQLIENCSKITKEIFELN------QSLLKKYPERKAP---FMVSTIDAEKYDLQENGVYELQRILFQKFNPTSSKLISCVG------------TWQLYLRDSGDHILHELKLAQENGYKLGLKLVRGAYIHSEKNRNQIIFGDKTG------TDENYDRIITQVVNDLIIN---GEDSYFGHLVVASHNYQSQMLVTNLLKSTQDNSYAKSNIVLGQLLGMADNVTYDLITNHGAKNIIKYVPWGPPLETKDYLLRRLQENGDAVR--SDNGWPLIKAIAKSIPKRVGL----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . . . .. . . . . . .. . . .* : : : : :: : * : ::* . . : .**: . : .: : *: :: :: *::* : *... . . : : : :: ::: :. :. : *: * :: . : : :: . . :::. :::: : : . *:.: . .: *: ::. : .* : *:*: *:: : *:* **::: .: ::: ::.:.: :* *******: .*: * : .. * *.* : :. : ::***** :: :. ::. . : :******.* ::: * :.. **:*:** *. ** ** ** . :: : * : : : : ", "identical_positions": 61, "similar_positions": 159, "identity": "8.82%" }, { "cls_id": "homologset.agr.FB:FBgn0003429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62976-1", "uniprot_id": "KCMA1_RAT", "id": "Q62976-1", "name": "Calcium-activated potassium channel subunit alpha-1", "aln": "MANGGGGGGGGSSGSSGGGGGGGGGETALRMSSNIHANHLSLDASSSSSSSSSSSSSSSSS-----VHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINN-GSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS-NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIK-IEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRR----------------------------------------------------------LEDEQPPTLSPKKKQR-------NGGMRNSPNTSP----------------------------------------------KLMRHDPLLIPG---NDQIDNMDSN--VKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDD---PDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSS-------SKKSSSVHSIPSTANRPNRPKSRESRDKQ-KKEMVYR----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08460-1", "uniprot_id": "KCMA1_MOUSE", "id": "Q08460-1", "name": "Calcium-activated potassium channel subunit alpha-1", "aln": "MANGGGGGGG----SSGGGGGGGGG-SGLRMSSNIHANNLSLDASSSSSSSSSSSSSSSSSSSSS-VHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINN-GSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS-NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIK-IEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRR----------------------------------------------------------LEDEQPPTLSPKKKQR-------NGGMRNSPNTSP----------------------------------------------KLMRHDPLLIPG---NDQIDNMDSN--VKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDD---PDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSS-------SKKSSSVHSIPSTANRPNRPKSRESRDKQNRKEMVYR----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12791-1", "uniprot_id": "KCMA1_HUMAN", "id": "Q12791-1", "name": "Calcium-activated potassium channel subunit alpha-1", "aln": "MANGGGGGGG----SSGGGGGGGGS--SLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINN-GSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS-NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIK-IEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESR----ILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQR-------NGGMRNSPNTSP----------------------------------------------KLMRHDPLLIPG---NDQIDNMDSN--VKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIIT---------------------------ELVNDTNVQFLDQDDDDD---PDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSS-------SKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7ZC96-1", "uniprot_id": "KCMA1_DANRE", "id": "B7ZC96-1", "name": "Calcium-activated potassium channel subunit alpha-1a", "aln": "------------------------------MSNNINFN----------KNPDSSVSIS------------KMD-VIIPFTPDVPCDNNGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCNIKNKEAQKVNNPITIQADGTTKTGNEKEEAPASEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSS-DPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIK-IEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESS----ILINPGNHVKMQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKR----------------------------------------------------------IEDEHPSTLSPKKKQR-------NGGMRNSPNCSP----------------------------------------------KMMRHDPLLIPG---NEQIESMDAN--VKRYDSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRREWETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIPIIT---------------------------ELVNDSNVQFLDQDDDDD---PDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRDRCRVAQLALYDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCLMQFDHNAGQSRASLSHSSHSSHSS-------SKKSSSVHSIPATNRQNRSSKAREARDKQNATRMNRMGPEKRWFTDEAENAYPRNIQIKPMSTHMANQVNQYKSTSSLIPPIREVEDEC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03720-1", "uniprot_id": "SLO_DROME", "id": "Q03720-1", "name": "Calcium-activated potassium channel slowpoke", "aln": "------------------------------MASGLIDTNFSSTLANGMSGCDQSTVES-----------LADDPTDSPFDAD---DCLKVRKYWCFLLSSIFTFLAGLLVVLLWRAFAF---VCCR-----KEPDLGPN------DPKQKEQKASRNKQEFEGTFMTEAKDWAGELISGQTTTGRILVVLVFILSIASLIIYFVDASSEEVERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPLD-FNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADS--KISINP-RGAKIQANTQGFFIAQSADEVKRAWFYCKACHEDIKDETLIKKCKCKN------------------LTVQPRSKFDDLDEHHPAPTFTPPELPKRVHVRGSVSGDITRDREDTNLLNRNVRRPNGTGNGTGGMHHMNNTAAAAAAAAAAGKQVNKVKPTVNVSRQVEGQVISPSQYNRPTSRSSGTGTQNQNGGVSLPAGIADDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSP------IVLQRRGSVYGANVPMIT---------------------------ELVNDSNVQFLDQDDDDD---PDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASS-KRYVITNPPDDFSLLPTDQVFVLMQFDP-GLEYKPPAVRAPAGGRGT-------NTQGSGVGGGGSNKDDNS-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4A6Z8-1", "uniprot_id": "KCNU1_RAT", "id": "D4A6Z8-1", "name": "Potassium channel subfamily U member 1", "aln": "------------------------------MSQTLLDN----------LNKKELTETS-----------------------------CTIEIQAAFILSSLATFFGGLIVLFIFRIALKISRNWKTVKGPRGILELFSS-------------RRIEVNPLRKLYFHGVFRERIEMLLSAQTIVGQVLVILVFVLSIGSLVIYFINSM-DPVRKCS-SYEDKIVHVDLSFNAFFSFYFGLRFWAAEDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPKILQILQVIKTSNSVKLSKLMSIVISTWFTAAGFLHLVENSGDPWLNGRNSQTMSYFESIYLVTATMSTVGFGDVVAKTSLGRIFIVFFTLGSLILFANYIPEMVELFSTRKKYNKPYEAVKGKKFIVVCGNITIDSVTAFLRNFLHRKAGEINIEIVFLGEAPPSVELETLLKCHTSCTTFVCGTALKFEDLKRVAVENAEACLILANPFCSDLHDEDNSNIMRVLSIKNYYPQTRVIIQMLQSQNKVFLSRIPNWNWSAGDNIICFAELKLGFIAQGCLVPGLCTFLTTLFIEQNQKV-FPKHPWQKHFLNGLKNKILTQRLSNDFVGMTFPQVSRLCFLKMHLMLIAIQHKP--LFHN-CCSLILNPSSQVRLNKDTLGFFIAESSKDVKRALFYCSNCHSDVCNPELIGKCGCKN-----------------------------------------------------------RSRQQLVAPTIMVMQ--------SSLNEFAP-------------------------------------------TAEIYTSISREQTSSVTILTTRNMPVDTADD--SDMLDSSGMFHWCRSMPLDKVVLKRSDKATHEFQNHIVACVFGDAHSSLMGLRNFVMPLRASNYTRQELKDIVFIGSLEYFQREWRFLRNFPKIHIMPGSALYTGDLHAVNVEQCSMCVILATPYKALSSQLLVDTETIMATLNIQALRISCPMSGSSKKEVNTSPTFS--------------KYEGKQRYQQIPILT---------------------------ELKNPSNIHFIEQMDGLDEAIKGTSLHLSTAFSTGTVFSGTFLDSLLATAFYNYHVLELLQMLVTGGINSQTEHCLVKEKLYEGNEGGATFLSGRTRCKLGLLSLDETILSDIKPKKTFGQLFCGSLDNLGILCVGLYRMMDEGE--HNSERKRFVITRPANECHLLPSDLVFCAIPFSITCDKSESNASIQDQDTTTN---VTS-MSQGSNFQGAQSALNEHSLSPASAMGEKKSPQLLNSRVYPLNLFDASDIDPGK------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54982-1", "uniprot_id": "KCNU1_MOUSE", "id": "O54982-1", "name": "Potassium channel subfamily U member 1", "aln": "------------------------------MSQTLLDS----------LNQKELTETS-----------------------------CTIEIQAAFILSSLATFFGGLIILFLFRIALKSSRSWKYVKGPRGLLELFSS-------------RRIEANPLRKLYFHGVFRQRIEMLLSAQTVVGQVLVILVFVLSIGSLVIYFINSM-DPVRRCS-SYEDKIVHVDLSFNAFFSFYFGLRFWAAEDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPKILQILQVIKTSNSVKLSKLLSIVISTWFTAAGFLHLVENSGDPWLNGRNSQTMSYFESIYLVTATMSTVGFGDVVAKTSLGRIFIVFFTLGSLILFANYIPEMVELFSTRKKYTKPYEAVKGKKFIVVCGNITVDSVTAFLRNFLHWKSGEINIEIVFLGETLPCLELETLLKCHTSCTNFVCGTALKFEDLKRVAVENSEACLILANHFCSDLHDEDNSNIMRVLSIKNYYPQTRVIIQILQSQNKVFLSKIPNWDWSAGDNILCFAELKLGFIAQGCLVPGLCTFLTTLFIEQNQKV-FPKHPWQKHFLNGLKNKILTQRLSNDFVGMTFPQVSRLCFVKLNLMLIAIQHKP--FFHS-CCTLILNPSSQVRLNKDTLGFFIADSSKAVKRAFFYCSNCHSDVCNPELIGKCNCKI-----------------------------------------------------------KSRQQLIAPTIMVMK--------SSLTDFTTSSHIHA-----------------------------------SMSTEIHTCFSREQPSLITITTNRPTTNDTVDD--TDMLDSSGMFHWCRAMPLDKVVLKRSEKAKHEFQNHIVVCVFGDAQCTLVGLRNFVMPLRASNYTRQELKDIVFIGSLEYFQREWRFLRNFPKIHIMPGSALYMGDLIAVNVEQCSMCVILATPYKALSSQILVDTEAIMATLNIQSLRITSPTPGSSKSEVKPSSAFD--------------SKERKQRYKQIPILT---------------------------ELKNPSNIHFIEQMGGLDGMLKGTSLHLSTSFSTGAVFSDTFLDSLLATSFYNYHVVELLQMLVTGGISSEMEHYLVKEKPYKTTDDYEAIKSGRTRCKLGLLSLDQTVLSGINPRKTFGQLFCGSLDNFGILCVGLYRMIDEEE--PSQEHKRFVITRPSNECHLLPSDLVFCAIPFNTTCGKSDSSPSIQAQNNSTN---ATTPLAQGSNFFDSHHADESHDLYPVDDTGERWS-QHHHSRVYPLDTLDASDIVQEK------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYU2-1", "uniprot_id": "KCNU1_HUMAN", "id": "A8MYU2-1", "name": "Potassium channel subfamily U member 1", "aln": "------------------------------MFQTKLRN----------ETWEDLPKMS-----------------------------CTTEIQAAFILSSFVTFFSGLIILLIFRLIWRSVKKWQIIKGTGIILELFTS-------------GTIARSHVRSLHFQGQFRDHIEMLLSAQTFVGQVLVILVFVLSIGSLIIYFINSA-DPVGSCS-SYEDKTIPIDLVFNAFFSFYFGLRFMAADDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPQILQILRAIKTSNSVKFSKLLSIILSTWFTAAGFIHLVENSGDPWLKGRNSQNISYFESIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTLGSLILFANYIPEMVELFANKRKYTSSYEALKGKKFIVVCGNITVDSVTAFLRNFLRDKSGEINTEIVFLGETPPSLELETIFKCYLAYTTFISGSAMKWEDLRRVAVESAEACLIIANPLCSDSHAEDISNIMRVLSIKNYDSTTRIIIQILQSHNKVYLPKIPSWNWDTGDNIICFAELKLGFIAQGCLVPGLCTFLTSLFVEQNKKV-MPKQTWKKHFLNSMKNKILTQRLSDDFAGMSFPEVARLCFLKMHLLLIAIEYKS--LFTDGFCGLILNPPPQVRIRKNTLGFFIAETPKDVRRALFYCSVCHDDVFIPELITNCGCKS-----------------------------------------------------------RSRQHITVPSVKRMK--------KCLKGISSR-----------------------------------------ISGQDSPPRVSASTSSISNFTTRTLQHDVEQD--SDQLDSSGMFHWCKPTSLDKVTLKRTGKSKYKFRNHIVACVFGDAHSAPMGLRNFVMPLRASNYTRKELKDIVFIGSLDYLQREWRFLWNFPQIYILPGCALYSGDLHAANIEQCSMCAVLSPPPQPSSNQTLVDTEAIMATLTIGSLQIDSSSDPSPSVSEETPGYTN--------------GHNEKSNCRKVPILT---------------------------ELKNPSNIHFIEQLGGLEGSLQETNLHLSTAFSTGTVFSGSFLDSLLATAFYNYHVLELLQMLVTGGVSSQLEQHLDKDKVYGVADSCTSLLSGRNRCKLGLLSLHETILSDVNPRNTFGQLFCGSLDLFGILCVGLYRIIDEEE--LNPENKRFVITRPANEFKLLPSDLVFCAIPFSTACYKRNEEFSLQKSYEIVNKASQTTETHSDTNCPPTIDSVTETLYSPVYSYQPRTN-SLSFPKQIAWNQSRTNSIISSQIPLGDNAKENERKTSDEVYDEDPFAYSEPL------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . .. * . .*: **: **:.**::::::* : . . : :: ::*.** .*::**:*** ***.:* ***::: : : *. :: :*: ** ** .** :** **.**: * **: *.** **:** *:* **. .*:**********: ...*** *. :***.*::: :* **.:*.*:****::**:****** .* : ::*: .:*:: .* ****:*** ..* *** *::** * .* :**. :**::**... .** . *::.*****:** :**: **::**: . ::: *:*** . * :*** ::* : : . * *: :: ** ** :..::***::** * * . ** :*****:***** *:* *::* :**..* .**.*:*. **: :*:**** *****.**. *:.*:::.** :. ..* : :*.. :: *: ** * *:.*. . .**: *::*:::**: * : :** ::. .* *****. .. *:** ***. **.*: * :* *: .... : : :. . : **:*****. . ::. * *. : : .*:*.*:*.* .. :****:********: :*** :*::**::*::***. * *:*:: :: * .* .** *.*:: *.** :*:. .. * *.* *:*:*.* :: : . ::*::* ** * :*::*::* .. : *.*:*: .*: *:.*: :.****::::::* : : *:: *:*** ..: * : : . :.* **::. ::* : :: . :*:** :*. .:**.*:**: * **:***.*. : ::*:* :* : *. : . ..:. ", "identical_positions": 335, "similar_positions": 326, "identity": "24.0%" }, { "cls_id": "homologset.agr.FB:FBgn0003430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88470-1", "uniprot_id": "FOXL2_MOUSE", "id": "O88470-1", "name": "Forkhead box protein L2", "aln": "----------------------------------------------------------MMASYPEPEDTAGTLLAPESGRAVK-------------EAEASPPSPGKGGG----TTPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSG--------IYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGE-RKGNYWTLDP--------------------------ACEDMFE-KGNYRRRRRMK------------------RPFRPPPAHFQPGKGLFGSGGAAGGCGVPGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPPPP--HPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLS------------------PASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LZJ6-1", "uniprot_id": "A0ABK0LZJ6_RAT", "id": "A0ABK0LZJ6-1", "name": "Forkhead box protein L2", "aln": "----------------------------------------------------------MMASYPEPEDTAGTLLSPESGRAVK-------------EAEASPPSPGKGGG----TAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSG--------IYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGE-RKGNYWTLDP--------------------------ACEDMFE-KGNYRRRRRMK------------------RPFRPPPAHFQPGKGLFGSGGGAGGCGVPGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPPP---HPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLS------------------PASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58012-1", "uniprot_id": "FOXL2_HUMAN", "id": "P58012-1", "name": "Forkhead box protein L2", "aln": "----------------------------------------------------------MMASYPEPEDAAGALLAPETGRTVK-------------EPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSG--------IYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGE-RKGNYWTLDP--------------------------ACEDMFE-KGNYRRRRRMK------------------RPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPP--PPP---HPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLS------------------PASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32030-1", "uniprot_id": "SLP1_DROME", "id": "P32030-1", "name": "Fork head domain transcription factor slp1", "aln": "--MVKSEMEFKSNFSIDAILAKKPIN---TATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNG--------IYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDP-GKGNYWILDP--------------------------SAEEVFIGETTGKLRRKNP------------------GASRTRLAAYR--QAIFSPMMAASPYGAP---ASSYGYPAVP---------------------------FAAAAAAALYQRMN-----------------PAAYQAAYQQMQYQQAP-----------------------------------QAHHHQAPHPAQMQG-----YPQQLN------------------AELFQRMQFFGKFPSS--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I9E1-1", "uniprot_id": "FOXH1_DANRE", "id": "Q9I9E1-1", "name": "Forkhead box protein H1", "aln": "---------MTKHWGGPGLLAPPVIT---VGEGAQRDHHLDCRIGYSSSKRSCHRSSNPLLELGGRLDKSTGMAQDSCYRAKATN-----------QGPWELQDGNSSGG-----KKKNYQRYPKPPYSYLAMIAMVIQNSPEKKLTLSE--------ILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVKVLKDPGKPQGKGNFWTVEVNRIPLELLKRQNTAVSRQDETIFAQDLAPYIFQGYSQPNKSKPLPPESSLPPVPTRQSPPPSEDPYRPKLDSTFAIDSLLHSLRPASSAGEGLRERESWGVGPPP---HTRSTTPPRPCNASYNGSSSASSVSPASDFSDEDWRGVTVVGKRSGDRGITSDAYSDSCPPPNKSSKRGNTPPWELPTSYAKYTPPNAVAPPSMRFNGNPFMPLGGIPFYGYGGAHVTTSHLIGHPYWPILPSGPVS-------------IQAPPLLMDLDSMLQSVPPNKSVFDALGSNNQTVHPSPNQYALQNGPSLCKYSL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLN-----LNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTN-GNNNPLLRNIIEG--------------------STYLREQRLQEEARLQQLDHLHTPLS-------------SSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIK--PPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . *: * . : : . : :::: : . . : *: . :.* : : . . :: . : . . : : . : : : ", "identical_positions": 5, "similar_positions": 36, "identity": "0.95%" }, { "cls_id": "homologset.agr.FB:FBgn0003435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQ48-1", "uniprot_id": "HNRPL_RAT", "id": "F1LQ48-1", "name": "Heterogeneous nuclear ribonucleoprotein L", "aln": "--MSRRLLPRAEKRRRRLEQRQQPDEQLRRAGAMVKMAAAGGGGGGGRYYGG---------------GNEGGRAPKRLKTENAGDQHGGGGGGGSGA---AGGGGG-------ENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDT-WDYTNPNLSGQGDP------------------------------GSNPNKRQRQPPLLGDHPAEYGEGRGFPSVDSRGSCAPARRPPRKFSPVLPLFPSHPPGGPHGGYHSHYH-DEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPDYGPHADSP-------VLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFM-FGQKMNVCVSKQPAIMPGQ-SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGK-SERSSSGLLEWDSKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R081-1", "uniprot_id": "HNRPL_MOUSE", "id": "Q8R081-1", "name": "Heterogeneous nuclear ribonucleoprotein L", "aln": "--MSRRLLPRAEKRRRRLEQRQQPDEQLRRAGAMVKMAAAGGGGGGGRYYGG---------------GNEGGRAPKRLKTENAGDQHGGGGGGGSGA---AGGGGG-------ENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDT-WDYTNPNLSGQGDP------------------------------GSNPNKRQRQPPLLGDHPAEYG-------------------------------------GPHGGYHSHYH-DEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPDYGPHADSP-------VLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFM-FGQKMNVCVSKQPAIMPGQ-SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGK-SERSSSGLLEWDSKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14866-1", "uniprot_id": "HNRPL_HUMAN", "id": "P14866-1", "name": "Heterogeneous nuclear ribonucleoprotein L", "aln": "--MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGG---------------GSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGG-------ENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDT-WDYTNPNLSGQGDP------------------------------GSNPNKRQRQPPLLGDHPAEYG-------------------------------------GPHGGYHSHYH-DEGYGPPPPHYEGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSP-------VLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFM-FGQKLNVCVSKQPAIMPGQ-SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGK-SERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M262-1", "uniprot_id": "A0ABK0M262_RAT", "id": "A0ABK0M262-1", "name": "", "aln": "-MSSTSSSPKEETYEEDREFESQAKRLKTEEGEIVYSAEESENRQEATPQAGSDSDSGGGDRGSGGGGGDGEEGDGGEEGDGEEGDEGDGDERGSGGDEGGSGGGPRSMPPSTEGGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADVPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDS-WDYTKPYL-GRRDR------------------------------GKG---RQRQ-AILGDHPSSFR---------------------------------------HDGYGSH-------GPLLPLPSRYRMG----------SRDTPELVAYPLPQASSSY-MHGGSPSG----SVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKL-FGKRLNVCVSKQHSVVPSQ-IFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921F4-1", "uniprot_id": "HNRLL_MOUSE", "id": "Q921F4-1", "name": "Heterogeneous nuclear ribonucleoprotein L-like", "aln": "MSSSSSSSPKEETYEEDREFESQAKRLKTEEGEIVYSAEESENRQEATPQAGSDSDSGGGDGGDGDGGSGGG-GDGEEGEGGEEGDEGDGDEGGSGGDEGGSGGGPRSMPLSTEGGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADVPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDS-WDYTKPYL-GRRDR------------------------------GKG---RQRQ-AILGDHPSSFR---------------------------------------HDGYGSH-------GPLLPLPSRYRMG----------SRDTPELVAYPLPQASSSY-MHGGSPSG----SVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKL-FGKRLNVCVSKQHSVVPSQ-IFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVV9-1", "uniprot_id": "HNRLL_HUMAN", "id": "Q8WVV9-1", "name": "Heterogeneous nuclear ribonucleoprotein L-like", "aln": "-MSSSSSSPRE-TYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRGG-----------------------------------GDG------------GGGGRSFSQ-PEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDS-WDYTKPYL-GRRDR------------------------------GKG---RQRQ-AILGEHPSSFR---------------------------------------HDGYGSH-------GPLLPLPSRYRMG----------SRDTPELVAYPLPQASSSY-MHGGNPSG----SVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKL-FGKRLNVCVSKQHSVVPSQ-IFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K7I2-1", "uniprot_id": "A0A0B4K7I2_DROME", "id": "A0A0B4K7I2-1", "name": "", "aln": "---------------------------------MPYNGASNGSGASGAGGGG----------------------------------------------------------------------------------------------------ATIVVTEGPQNKKIRTGVQQPGENDVHMHARSTPQQNQQQALMNKSNDDLRRKRPETTRP---NHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIFKKNGVQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNVYKNEPDTSWDYTLSTVKEIGNGRSPLLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQQQLVAP----------------------------AQSHNLYQFKEPPLLGPGAAFPPFGAPEYHTTTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLPDHSPSFKEYTGSKNNRFLSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVP-ATSVRLFPLK-TERSSSGLIEFSNISQAVLAIMKCNHLPIEGKGTKFPFIMKLCFSSSKSMNGAWNNAASEGMIEKENEVDTKVDIYN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . .* . ::: :: :. . : * * : *:.* *... : :: . * :**::* **:*.**.***:.:*:* * * *****::**:******:.: .* :*: *******:*******:**:* :*** :*: *: **** . : : . :*:* . ** *. * : *. * . : . * . . .* *:** **.: . * .::**:.*****: ::**:*: *:*:*:*.* **:*.: **** : * ::::..*** : : * * : *:*::: *:**** :. **:** ** ** :**::*.* :**: : : : * . ::* * : :: ***:*:. ::*: :: ** :. . *: :*****::. ", "identical_positions": 144, "similar_positions": 138, "identity": "20.06%" }, { "cls_id": "homologset.agr.FB:FBgn0003444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97698-1", "uniprot_id": "SMO_RAT", "id": "P97698-1", "name": "Protein smoothened", "aln": "MAAGRPVRGPELAPRRLLQLLLLVLLGGRGRGAALSGNVTGPGPRS----------------AGGSARRNAPVTSPPPPLLSHCGRAAHCEPLR--YNVCLGSALPYGATTTLLAGDSDSQEEAHSKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCE----NDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDHFPEGCPNEVQNIKFNSSGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRFGEPTSSETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKKPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRLTGHSDDEPKRIKKSKMIAKAFSKRRELLQNPGQELSFSMHTVSHDGPVAGLAFELNEPSADVSSAWAQHVTKMVARRGAILPQDVSVTPVATPVPPEEQANLWLVEAEISPELEKR-----------------------------LGRKKKRRKRKKEVCPLGPAPELHHSAPVPATSAVPRLPQLPRQKCLVAANAWGTG------------EPCRQGAWTVVSNPFCPEPSPHQDPFLPGASAPRVWAQGRLQGLGSIHSRTNLMEAELLDADSDF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56726-1", "uniprot_id": "SMO_MOUSE", "id": "P56726-1", "name": "Protein smoothened", "aln": "MAAGRPVRGPELAPRRLLQLLLLVLLGGPGRGAALSGNVTGPGPHS----------------ASGSSRRDVPVTSPPPPLLSHCGRAAHCEPLR--YNVCLGSALPYGATTTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCE----NDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDHFPEGCPNEVQNIKFNSSGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRFGEPTSSETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKKPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRLTGHSDDEPKRIKKSKMIAKAFSKRRELLQNPGQELSFSMHTVSHDGPVAGLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDVSVTPVATPVPPEEQANMWLVEAEISPELEKR-----------------------------LGRKKKRRKRKKEVCPLRPAPELHHSAPVPATSAVPRLPQLPRQKCLVAANAWGTG------------ESCRQGAWTLVSNPFCPEPSPHQDPFLPGASAPRVWAQGRLQGLGSIHSRTNLMEAEILDADSDF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99835-1", "uniprot_id": "SMO_HUMAN", "id": "Q99835-1", "name": "Protein smoothened", "aln": "MAAARPARGPELP---LLGLLLLLLLGDPGRGAASSGNATGPGPRS----------------AGGSARRSAAVTGPPPP-LSHCGRAAPCEPLR--YNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCE----NDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRLTGQSDDEPKRIKKSKMIAKAFSKRHELLQNPGQELSFSMHTVSHDGPVAGLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDISVTPVATPVPPEEQANLWLVEAEISPELQKR-----------------------------LGRKKKRRKRKKEVCPLAPPPELHPPAPAPST--IPRLPQLPRQKCLVAAGAWGAG------------DSCRQGAWTLVSNPFCPEPSPPQDPFLPSAPAPVAWAHGRRQGLGPIHSRTNLMDTELMDADSDF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91682-1", "uniprot_id": "SMO_DROME", "id": "P91682-1", "name": "Protein smoothened", "aln": "MQYLNFPRMPNIMMFLEVAILCLWVVADASASSAKFGSTTPASAQQSDVELEPINGTLNYRLYAKKGRDDKPWFDGLDSRHIQCVRRARCYPTSNATNTCFGSKLPYELSSLDLT-DFHTEKELNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMCRITMEPCRILYNTTFFPKFLRCNETLFPTKCTNGARGMKFNGTGQCLSPLVPTDTSASYYPGIEGCGVRCKDPLYTDDEHRQIHKLIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWLLQFTSGSREDIVCRKDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFLTYAWH--WRAMGHVQDRIDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILIGGYFITRGMVMLFGLKHFANDIKSTSASNKIHLIIMRMGVCALLTLVFILVAIACHVTEFRHADEWAQSFRQFIICKISSVFEE-----KSSCRIENRPSVGVLQLHLLCLFSSGIVMSTWCWTPSSIETWKRYIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDKGRLSITLYNTHTDPVGLNFDVNDLNSSETNDISSTWAAYLPQCVKRRMALTGAATGNSSSHGPRKNSLDSEISVSVRHVSVESRRNSVDSQVSVKIAEMKTKVASRSRGKHGGSSSNRRTQRRRDYIAAATGKSSRRRESSTSVESQVIALKKTTYPNASHKVGVFAHHSSKKQHNYTSSMKRRTANAGLDPSILNEFLQKNGDFIFPFLQNQDMSSSSEEDNSRASQKIQDLNVVVKQQEISEDDHDGIKIEELPNSKQVALENFLKNIKKSNESNSNRHSRNSARSQSKKSQKRHLKNPAADLDFRKDCVKYRSNDSLSCSSEELDVALDVGSLLNSSFSGISMGKPHSRNSKTSCDVGIQANPFELVPSYGEDELQQAMRLLNAASRQRTEAANEDFGGTELQGLLGHSHRHQREPTFMSESDKLKMLLLPSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * *:: : :* * ::.. . .:* *..* ...:. . ..* . . . . :* * * * * *.*:** *** :: *: * .:::* :.** : .*::.*:***.***:****: **** :* * *** :*: * ** *: . :*.****. ** *.* .:.:***.:*** *** **.. *:* .:****::*::**:*: **:::*. *. *:: *..**.::**. **:*:*:*****:**:* **::..:*** ** .*:*.:**** ***:* .***:.*.***::***:*** * **:****.****** ::*:* . : :. * *****::****:***:: :*.::***:*: ******* *: ***::*.*: *:::****: **:: **.:* .: * .*:.**: ::*:*: .:*:: *:*::::**. :* : ** :***::::*: . .: ..*.*:****: * :::*:.:*.:**.**** ** ::: *:* : *:. * :: * *:**::::**::: :: .::: .. * .: .. : *:**:** ::.: * ** *: . :. * . :::: : .:* * .:. .*:.:**: ... .. . . .:.. : : . *. . *.. * :. ... * . : * * : . *** . . ... :. *:. . ::. : :. *.. ", "identical_positions": 262, "similar_positions": 287, "identity": "25.1%" }, { "cls_id": "homologset.agr.FB:FBgn0003447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85845-1", "uniprot_id": "FSCN1_RAT", "id": "P85845-1", "name": "Fascin", "aln": "MT--------ANG--TAEAVQ---IQFGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGPYLAADKDGNVTCEREVPDGDCRFLVVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATGGVQSTASTKNASCYFDIEWCE-RRITLRASNGKFVTAKKNGQLAATVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFND-GAYNIKDSTGKYWTVGSDSSVTSSSDTPVDFFLEFCDYNKVALKVG-GRYLKGDHAGVLKACAETIDPATLWEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61553-1", "uniprot_id": "FSCN1_MOUSE", "id": "Q61553-1", "name": "Fascin", "aln": "MT--------ANG--TAEAVQ---IQFGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPDGDCRFLVVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATGGVQSTASTKNASCYFDIEWCD-RRITLRASNGKFVTAKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFND-GAYNIKDSTGKYWTVGSDSSVTSSSDTPVDFFLEFCDYNKVALKVG-GRYLKGDHAGVLKACAETIDPASLWEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16658-1", "uniprot_id": "FSCN1_HUMAN", "id": "Q16658-1", "name": "Fascin", "aln": "MT--------ANG--TAEAVQ---IQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRD-RRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFND-GAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVG-GRYLKGDHAGVLKASAETVDPASLWEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MPL5-1", "uniprot_id": "A0A0A0MPL5_DANRE", "id": "A0A0A0MPL5-1", "name": "Fascin", "aln": "MS--------SEG--IGETLV---IRFGLINADNKYLTAEMFGFKINASASSMKKKQVWTLEQSGDHGDSNAVFIKSHLGRYLASDKDGKVTADSEQPGPDCRFLVIAHDDG--RWSLQSEPHARYLGGTEDRIACFAQSISPAEKWNVHLAVHPQVNVYSIARKRYAHLCAD-RNELAVDRDVPWGVDSLLTLVYLDH---RYHLQTADNRFLSCGGTLTAKPDRDTGFTLEFRAGKVAFRDATGKYIAPTGPTGTMKSGRSARVGKDELFVLEQSHGQVVLTAS-NDRNISMRQGVDLSANQDEESDQEVFQMEMDRESKRCAFRSFNGRYWSLTSSGAIQCSALTKSPSCFFDLEWKG-SKVALKASNGKYLAAKKNGQLAAAVDSAGEQEEFVLKLINRPLIVLRGEHGFIGCRKQGTGTLDSNRSSYDVFQLEYNN-NAYSLRDSVGKYWTVESDGSVISSGAAPVYFHFEFCDFNKVAIKTKEGKYLKGDHAGVLKASAQGIADATLWEY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZX02-1", "uniprot_id": "D3ZX02_RAT", "id": "D3ZX02-1", "name": "Fascin", "aln": "MP--------TNG--LHQVLK---IQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQ-GTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDG--RWVLQSEPHGRFFGGVEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQ-EDEMAADGDMPWGVDALLTLIFQSR---RYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQSHPQVVLVAA-NHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHG-RRVALKASNGRYVCMKKNGQLAAISDFVGEDELFILKLINRPILVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLSFRD-GAYQIRGRGGGFWYTGSHGSVCSDGDLAEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32M02-1", "uniprot_id": "FSCN2_MOUSE", "id": "Q32M02-1", "name": "Fascin-2", "aln": "MP--------TNG--LHQVLK---IQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQ-GTAVLFRSSHLGRYLSAEEDGRVACEMDQPGRDCRFLVLPQPDG--RWVLQSEPHGRFFGGIEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQ-EDEMAADGDMPWGVDALVTLIFQSR---RYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPSKDELFDLEQSHPQVVLVAA-NRRYISVRQGINVSANQDEELGHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHG-RRVALKASNGRFVCMKKNGQLAAISDFVGEDELFTLKLINRPLLVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLSFRD-GAYQIRGRGGGFWYTGSHGSVCSDGDLAEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPVGEALWEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14926-1", "uniprot_id": "FSCN2_HUMAN", "id": "O14926-1", "name": "Fascin-2", "aln": "MP--------TNG--LHQVLK---IQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQ-GTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDG--RWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPR-EDEMAADGDKPWGVDALLTLIFRSR---RYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAA-NHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRG-RRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHR-GSNQLDTNRSVYDVFHLSFSD-GAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YWM1-1", "uniprot_id": "A0A8M6YWM1_DANRE", "id": "A0A8M6YWM1-1", "name": "Fascin", "aln": "MS--------TNG--ISAALK---LQFGLINHENRYLTAEAFGFKINASGNSMKKKQIWTLEQDPD---SQVVFLRSHLGRYLSSDKDGKVRCEEEVPNTDCRFLIVMQSDG--RWALQSEPYLRYFGGSEEYLSCFAQTIGESELWALHLALHPQANLLSVARKRYAHLSTQ-EDEISMDSNIPWGVDSLITLVYLEG---KYSLKTCDNRFLKNDGKLVMEHGPNTSFTLELKSGKLAFKDCEGKYLSPNGPTGTLKSGRCTRPGKDELFDLEESHPQVVFQAA-NKRYVSIRQGVCISANQDDETDMETFQMEIDKETKKCMFRTNGGNYWTLVTHGGILSSATEIEENTMFDIEWLG-RRIALKASNGKYVCTKKNGQLAAVSDSLGEDEQFVLKLINRPILVLRGENGFVCHHK-NSNTLHGSRSFYDIFTLLFSD-GGYQIKSGNQKFWYVSSSGLVCTDGDKPEDFFFEFVEYGRVGIKAQNGKYLRGDQGGTLMGDGLSVNASSLWEH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24524-1", "uniprot_id": "SING_DROME", "id": "Q24524-1", "name": "Protein singed", "aln": "MNGQGCELGHSNGDIISQNQQKGWWTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLE--PSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSES-QDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEIAKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* :**:. .:*:*** ****:**.. *:*:** *.** . : ***. **: :: *.* .: : . ..** : ** ** *:.*. ::** : : * * : . :* * :*:* :**.:: *: *:*:.**. :*: * : *** *:*.** : :* ::: : ::* .* * :: * :.*::*::* *:*::* *. ..:*: : : :**** **:* *. : *. * * :* :**: ::****: *.* :: * .::: : : . ** * : *.: .:. . *:: * ::::*.**::: *:.*:* * : . * : *****::*:: .**: : . *. .:: *: : : : . :: :* . . . . * :*: : :: :: *:** . * : : **.", "identical_positions": 127, "similar_positions": 161, "identity": "24.61%" }, { "cls_id": "homologset.agr.FB:FBgn0003448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08954-1", "uniprot_id": "SNAI2_RAT", "id": "O08954-1", "name": "Zinc finger protein SNAI2", "aln": "---------------------------------------MPRSFLVKKH------------------FNASKKPN-YSELDTHTVIISP------YLCESYPMP-----------VIP------KPEILTSGAYSPITVWTS-AVPFHSPLPSGLSPLTGYSSSLGRVSPLPSSDTSSKDHSGSESP---------------ISDEEER--------------LQPKLSDPHAIEAE------KFQCNLCNKTYSTFSGLAKHKQLHCDA----QARKSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCVAH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97469-1", "uniprot_id": "SNAI2_MOUSE", "id": "P97469-1", "name": "Zinc finger protein SNAI2", "aln": "---------------------------------------MPRSFLVKKH------------------FNASKKPN-YSELDTHTVIISP------YLYESYPIP-----------VIP------KPEILTSGAYSPITVWTSSAAPLHSPLPSGLSPLTGYSSSLGRVSPPPSSDTSSKDHSGSESP---------------ISDEEER--------------LQPKLSDPHAIEAE------KFQCNLCNKTYSTFSGLAKHKQLHCDA----QSRKSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCVAH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43623-1", "uniprot_id": "SNAI2_HUMAN", "id": "O43623-1", "name": "Zinc finger protein SNAI2", "aln": "---------------------------------------MPRSFLVKKH------------------FNASKKPN-YSELDTHTVIISP------YLYESYSMP-----------VIP------QPEILSSGAYSPITVWTT-AAPFHAQLPNGLSPLSGYSSSLGRVSPPPPSDTSSKDHSGSESP---------------ISDEEER--------------LQSKLSDPHAIEAE------KFQCNLCNKTYSTFSGLAKHKQLHCDA----QSRKSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCVAH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08044-1", "uniprot_id": "SNAI_DROME", "id": "P08044-1", "name": "Protein snail", "aln": "MAANYKSCPLKKRPIVFVEERLPQTEALALTKDSQFAQDQPQDLSLKRGRDEETQDYQQPEPKRDYVLNLSKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNCTITIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.: :*: :* **.*: *. .::: ::** ** . : . * :. :: :.. .**:. : * : :*. *.::. .* . . *.*...*. .:***. : ** : . :* . * * :*:*: *:* *** **:**:*:** * * :*:.**: *.* *.::************** * *************************.**.* *:********** *** ***** *: * *:*******:**..*.* :: ", "identical_positions": 127, "similar_positions": 78, "identity": "32.56%" }, { "cls_id": "homologset.agr.FB:FBgn0003449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U214-1", "uniprot_id": "Q5U214_RAT", "id": "Q5U214-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------------MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09012-1", "uniprot_id": "SNRPA_HUMAN", "id": "P09012-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------------MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62189-1", "uniprot_id": "SNRPA_MOUSE", "id": "Q62189-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "------------MATIATMPVPETRANHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRIMKMRGQAFVIFKEVTSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTYVERDRKREKRKPKSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMPQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CQI7-1", "uniprot_id": "RU2B_MOUSE", "id": "Q9CQI7-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "---------------------MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTMEQAAAA--------------------------------------------------ANKKPGQGTPNAANTQ----GTAAPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DEQ4-1", "uniprot_id": "B5DEQ4_RAT", "id": "B5DEQ4-1", "name": "", "aln": "---------------------MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTMEQAAAA--------------------------------------------------ANKKPGQGTPNSANTQ----GNAAPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08579-1", "uniprot_id": "RU2B_HUMAN", "id": "P08579-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "---------------------MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATT--------------------------------------------------TNKKPGQGTPNSANTQ----GNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GDR2-1", "uniprot_id": "R4GDR2_DANRE", "id": "R4GDR2-1", "name": "", "aln": "---------------------MDIRPNHTIYINNVNDKIKKEELKRSLYALFSQFGQIMDIVALKTMRMRGQAFVIFKELSAATNALRQLQGFPFYNKPMRIQYAKTDSDLVSKMRGTYGDKEKKKEKKK-KAQEQAAAN--------------------------------------------------ANKKP----AGAVNTQ----PPPPATVQIPDNPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGKHDISFVEFESEAQAGVAKDALQGFRITATCAMKITYAKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43332-1", "uniprot_id": "SNRPA_DROME", "id": "P43332-1", "name": "U1 small nuclear ribonucleoprotein A", "aln": "---------------------MEMLPNQTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEIGSASNALRTMQGFPFYDKPMQIAYSKSDSDIVAKIKGTFKERPKKVKPPKPAPGTDEKKD--------------------------------------------------KKKKP----SSAENSN--------PNAQT-EQPPNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPNRHDIAFVEFTTELQSNAAKEALQGFKITPTHAMKITFAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40567-1", "uniprot_id": "MSL1_YEAST", "id": "P40567-1", "name": "U2 small nuclear ribonucleoprotein B''", "aln": "MVEPARKKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMN-FKKQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFSKSETKTL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*:*:.::*:**: :.*: .*: :*: **.::.: : *****: :: : :: * ::* *:.**::: ::*:::. : ", "identical_positions": 21, "similar_positions": 43, "identity": "7.0%" }, { "cls_id": "homologset.agr.FB:FBgn0003460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V970-1", "uniprot_id": "G3V970_RAT", "id": "G3V970-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNS---VLLLQSNMGHARSSNYSL---PG-----LTASQPSHG-------------------LQAHQHQLQDSLLGPLTSS-LVDLGS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62231-1", "uniprot_id": "SIX1_MOUSE", "id": "Q62231-1", "name": "Homeobox protein SIX1", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNS---VLLLQSNMGHARSSNYSL---PG-----LTASQPSHG-------------------LQAHQHQLQDSLLGPLTSS-LVDLGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15475-1", "uniprot_id": "SIX1_HUMAN", "id": "Q15475-1", "name": "Homeobox protein SIX1", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNS---VLLLQGNMGHARSSNYSL---PG-----LTASQPSHG-------------------LQTHQHQLQDSLLGPLTSS-LVDLGS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZ04-1", "uniprot_id": "SIX1B_DANRE", "id": "Q6NZ04-1", "name": "Homeobox protein six1b", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENSENNNTGANKQNQLSPLDGGKSLMSSSEDEFSPPQSPDQNS---VLLLQGNMSHPGASAYSM---TG-----LGAAQSVHG-------------------MQGHPHQLQDSLLGPLTSS-LVDLGS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DHF9-1", "uniprot_id": "SIX1A_DANRE", "id": "Q6DHF9-1", "name": "Homeobox protein six1a", "aln": "----------------------------------------------------------------------------------------------MSILPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESYQFSTHNHPKMQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENGENNGVGG-KQSQRSPLDGVKSLMSSSEDEFSPPQSPEHSS---VLLLQGTMNNPAAPAYPM---PG-----LGAPHPLHG-------------------MQGHPHQIQDSLLGSLTSS-LVDLGS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LM21-1", "uniprot_id": "A0ABK0LM21_RAT", "id": "A0ABK0LM21-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERY-EENSENSNSSSHNPLASSLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPPGLPSLHSLGHPPGP----SAVPVPVPGGGGA--------------DPLQHHHSLQDSILNPMSAN-LVDLGS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62232-1", "uniprot_id": "SIX2_MOUSE", "id": "Q62232-1", "name": "Homeobox protein SIX2", "aln": "----------------------------------------------------------------------------------------------MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENSENSNSSSHNPLASSLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPPGLPSLHSLGHPPGP----SAVPVPVPGGGGA--------------DPLQHHHSLQDSILNPMSAN-LVDLGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPC8-1", "uniprot_id": "SIX2_HUMAN", "id": "Q9NPC8-1", "name": "Homeobox protein SIX2", "aln": "----------------------------------------------------------------------------------------------MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER---ENNENSNSNSHNP----LNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPP-GLPSLHSLGHPPGP----SAVPVPVPGGGGA--------------DPLQHHHGLQDSILNPMSAN-LVDLGS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27350-1", "uniprot_id": "SO_DROME", "id": "Q27350-1", "name": "Protein sine oculis", "aln": "MLQHPATDFYDLAAANAAAVLTARHTPPYSPTGLSGSVALHNNNNNNSSTSNNNNSTLDIMAHNGGGAGGGLHLNSSSNGGGGGGVVSGGGSGGRENLPSFGFTQEQVACVCEVLQQAGNIERLGRFLWSLPQCDKLQLNESVLKAKAVVAFHRGQYKELYRLLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPREKRDLAEATGLTTTQVSNWFKNRRQRDRAAEHKDGSTDKQHLDSSSDSEMEGSMLPSQSAQHQQQQQQQQHSPGNSSGNNNGLHQQQLQHVAAEQGLQHHPHQPHPASNIANVAATKSSGGGGGGGVSAAAAAQMQMPPLTAAVAYSHLHSVMGAMPMTAMYDMGEYQHL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:*****************.**:*********** *::*: ****************:::***::** ::**.:**.*:* *******:**************************:****************.***:**:***********:*************************** *: :: :.. .. . : ..::: :* :. :.. *. :. .. .. . * : .*::..:. . : *:*. ", "identical_positions": 160, "similar_positions": 65, "identity": "38.46%" }, { "cls_id": "homologset.agr.FB:FBgn0003462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08228-1", "uniprot_id": "SODC_MOUSE", "id": "P08228-1", "name": "Superoxide dismutase [Cu-Zn]", "aln": "MAMKAVCVLKGDGPVQGTIHFEQKASGEPVVLSGQITG-LTEGQHGFHVHQYGDNTQGCTSAGPHFNPHSKKHGGPADEERHVGDLGNVTAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07632-1", "uniprot_id": "SODC_RAT", "id": "P07632-1", "name": "Superoxide dismutase [Cu-Zn]", "aln": "MAMKAVCVLKGDGPVQGVIHFEQKASGEPVVVSGQITG-LTEGEHGFHVHQYGDNTQGCTTAGPHFNPHSKKHGGPADEERHVGDLGNVAAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00441-1", "uniprot_id": "SODC_HUMAN", "id": "P00441-1", "name": "Superoxide dismutase [Cu-Zn]", "aln": "MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKG-LTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O73872-1", "uniprot_id": "SODC_DANRE", "id": "O73872-1", "name": "Superoxide dismutase [Cu-Zn]", "aln": "MVNKAVCVLKGTGEVTGTVYFNQEGEKKPVKVTGEITG-LTPGKHGFHVHAFGDNTNGCISAGPHFNPHDKTHGGPTDSVRHVGDLGNVTADASGVAKIEIEDAMLTLSGQHSIIGRTMVIHEKEDDLGKGGNEESLKTGNAGGRLACGVIGITQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P61851-1", "uniprot_id": "SODC_DROME", "id": "P61851-1", "name": "Superoxide dismutase [Cu-Zn]", "aln": "MVVKAVCVINGD--AKGTVFFEQESSGTPVKVSGEVCG-LAKGLHGFHVHEFGDNTNGCMSSGPHFNPYGKEHGAPVDENRHLGDLGNIEATGDCPTKVNITDSKITLFGADSIIGRTVVVHADADDLGQGGHELSKSTGNAGARIGCGVIGIAKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00445-1", "uniprot_id": "SODC_YEAST", "id": "P00445-1", "name": "Superoxide dismutase [Cu-Zn]", "aln": "-MVQAVAVLKGDAGVSGVVKFEQASESEPTTVSYEIAGNSPNAERGFHIHEFGDATNGCVSAGPHFNPFKKTHGAPTDEVRHVGDMGNVKTDENGVAKGSFKDSLIKLIGPTSVVGRSVVIHAGQDDLGKGDTEESLKTGNAGPRPACGVIGLTN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.*::* . * : *:* . *. : .: * . . :***:* :** * ** ::****** : **.* *. **:**:**: : . :. .: * :.* * .::**::*:* ****:*. * * .***** * .*****::: ", "identical_positions": 59, "similar_positions": 46, "identity": "37.82%" }, { "cls_id": "homologset.agr.FB:FBgn0003463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63148-1", "uniprot_id": "CHRD_RAT", "id": "Q63148-1", "name": "Chordin", "aln": "--------------------------------------------------MPSLPAPPAPRLLLGLLLLGSRPAGGTGPEAPALPIRSEKEPLPVR-GAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQDAERSNLDPQPAGLVFEYPRDPEHRSYSDRGEPGTGERTRGDGHTEDFVALLTG------PRTQAVARARVSLLRSSLRFSIS-YQRLDRPSRVRFTDPTGNILFEHPAAPTQD----------GLVCGVWRAVPRLSVRLLRAEQLRVALVTPTHPSEE--VWGPLIWQGALTAETFSAILTLE------DPLQRGVGGIALLTLS-DTEDALHFLLLFRGLL----GGLAHVPLKLQILHQGQLLRELQANAS--AQEPGFAEVLPSLTDQEMDWLVLGELQMVLEKMGGPELRISGYITTRQSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVIGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGVCSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTALCYSGHSAHYDRLPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGM-------PGPQRLLKGFYGSEAQGVVKDLEPVLLRHLTQGTASLLITTKSNPRGELRGQVHIASQCEVGGLRLASEGVRMSLAPNGEAATSPMLPAGPGPEAPVPAKHGSSGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQALD---QCCPVCPEKQRSRDLPSLP-NLEPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCTCKGATGEVHCEKVQCPRLACAQPVRANPTD--CCKQCPVG------------SGTHAKLGDPMQADGPR---------GCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSPPLSCGS-------------GKESRCCSHCTAQR--SSETRTLPELEKEAQRS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0E2-1", "uniprot_id": "CHRD_MOUSE", "id": "Q9Z0E2-1", "name": "Chordin", "aln": "--------------------------------------------------MPSLPAPPAPRLLLGLLLLGSRPASGTGPEPPALPIRSEKEPLPVR-GAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQ--ERSNLDPQPAGLVFEYPRDPEHRSYSDRGEPGVGERTRADGHT-DFVALLTG------PRSQAVARARVSLLRSSLRFSVS-YQRLDRPSRVRFTDPTGNILFEHPATPTQD----------GLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGE--VWGPLIWQGALAAETFSAILTLE------DPLQRGVGGIALLTLS-DTEDSLHFLLLFRGLL----GGLAQAPLKLQILHQGQLLRELQANTS--AQEPGFAEVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYITTRQSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQPGGHMAVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTALCYSGHSARYDRLPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGM-------PGPQRLLKGFYGSEAQGVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLASEGVQMPLAPNGEAATSPMLPAGPGPEAPVPAKHGSPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCICQRRTVICDPVVCPPPSCPHPVQALD---QCCPVCPEKQRSRDLPSLP-NLEPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCTCKGATGEVHCEKVQCPRLACAQPVRANPTD--CCKQCPVG------------SGTNAKLGDPMQADGPR---------GCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSPPLSCGS-------------GKESRCCSHCTAQR--SSETRTLPELEKEAEHS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2X0-1", "uniprot_id": "CHRD_HUMAN", "id": "Q9H2X0-1", "name": "Chordin", "aln": "--------------------------------------------------MPSLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVR-GAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQ--ERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEERARGDGHT-DFVALLTG------PRSQAVARARVSLLRSSLRFSIS-YRRLDRPTRIRFSDSNGSVLFEHPAAPTQD----------GLVCGVWRAVPRLSLRLLRAEQLHVALVTLTHPSGE--VWGPLIRHRALAAETFSAILTLE------GPPQQGVGGITLLTLS-DTEDSLHFLLLFRGLLEPRSGGLTQVPLRLQILHQGQLLRELQANVS--AQEPGFAEVLPNLTVQEMDWLVLGELQMALEWAGRPGLRISGHIAARKSCDVLQSVLCGADALIPVQTGAAGSASLTLLGNGSLIYQVQVVGTSSEVVAMTLETKPQRRDQRTVLCHMAGLQPGGHTAVGICPGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVAALPYCGHSARHDTLPVPLAGALVLPPVKSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGT-------PGPRRLLKGFYGSEAQGVVKDLEPELLRHLAKGMASLMITTKGSPRGELRGQVHIANQCEVGGLRLEAAGAEGVRALGAPDTASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD---QCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTD--CCKQCPVG------------SGAHPQLGDPMQADGPR---------GCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS-------------GKESRCCSRCTAHRRPAPETRTDPELEKEAEGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57472-1", "uniprot_id": "CHRD_DANRE", "id": "O57472-1", "name": "Chordin", "aln": "---------------------------------------------------------MMEGLLWILLSVIIASVHGSRLKTPALPIQPEREPMISK-GLSGCSFGGRFYSLEDTWHPDLGEPFGVMHCVMCHCE-PQRSRRGKVFGKVSCRNMKQDCPDPTCDDPVLLPGHCCKTCPK-GDSGRKEVESLFDFFQEKDDDLHKSYNDRSYISSEDTSTRDSTTTDFVALLTGVTDSWLPSSSGVARARFTLSRTSLTFSIT-FQRINRPSLIAFLDTDGNTAFEFRVPQADN----------DMICGIWKNVPKPHMRQLEAEQLHVSMTTADNRKEE--LQGRIIKHRALFAETFSAILTS-------DEVHSGMGGIAMLTLS-DTENNLHFILIMQGLVP---PGSSKVPVRVKLQYRQHLLREIRANIT--ADDSDFAEVLADLNSRELFWLSRGQLQISVQTEGQTLRHISGFISGRRSCDTLQSVLSSGAALTAGQTGGVGSAVFTLHPNGSLDYQLLVAGLSSAVLSVSIEMKPRRRNKRSVLYELSAVFT-DQRAAGSCGRVEARHTHMLLQNELFINIATALQPDGELRGQIRLLPYNGLDARRNELPVPLAGVLVSPPVRTGAAGHAWVSVDPQCHLHYEIIVNGLSKSEDASISAHLHGLAEIGEMDDSSTNHKRLLTGFYGQQAQGVLKDISVELLRHLNEGTAYLQVSTKMNPRGEIRGRIHVPNHCES-------------PAPRAEFLEEPEFEDLLFTREPTELRKDT---HTHVHSCFFEGEQHTHGSQWTPQYN-TCFTCTCQKKTVICDPVMCPTLSCTHTVQPED---QCCPICEEKKESKETAAVEKVEENPEGCYFEG-----DQKMHAPGTTWHPFVPPFGYIKCAVCTCKGSTGEVHCEKVTCPPLTCSRPIRRNPSD--CCKECPPE------------ETPPLEDEEMMQADGTR---------LCKFGKNYYQNSEHWHPSVPLVGEMKCITCWCDHGVTKCQRKQC-PLLSCRNP-----------IRTEGKCCPECIEDFMEKEEMAKMAEKKKSWRH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24025-1", "uniprot_id": "SOG_DROME", "id": "Q24025-1", "name": "Dorsal-ventral patterning protein Sog", "aln": "MANKLRKSNAIEWATATGTVPLLERSCCHSEDAALEPQASKTSHREQAPILRHLSQLSHLLIIAGLLIVCLAGVTEGRRHAPLMFEESDTGRRSNRPAVTECQFGKVLRELGSTWYADLGPPFGVMYCIKCECVAIPKKRR--IVARVQCRNIKNECPPAKCDDPISLPGKCCKTCPG--DRNDTDVALDVPVPNEEEERNMKHYAALLTGRTSYFLKGEEMKSMYTTYNPQ---------NVVATARFLFHKKNLYYSFYTSSRIGRPRAIQFVDDAGVILEEHQLETTLAGTLSVYQNATGKICGVWRRVPRDYKRILRDDRLHVVLLWGNKQQAELALAGKVAKYTALQTELFSSLLEAPLPDGKTDPQLAGAGGTAIVSTSSGAASSMHLTLVFNGVFGAEEYADAALSVKIELAERKEVIFDEIPRVRKPSAEINVLELSSPISIQNLRLMSRGKLLLTVESKKYPHLRIQGHIVTRASCEIFQTLLAPHSAESSTKS--SGLAWVYLNTDGSLAYNIETEHVNTRDRPNISLIEEQ--GKRKAKLEDLTPSFNFNQAIGSVEKLGPKVLESLYAGELGVNVATEHETSLIRG---RLVPRPVADARDSAEPILLKRQEHTDAQNPHAVGMAWMSIDNECNLHYEVTLNGVPAQDLQLYLEEKPIEAIG------APVTRKLLEEFNGSYLEGFFLSMPSAELIKLEMSVCYLEVHSKHSKQLLLRGKLKST------------------------KVPGHCFPVYTDNNVPVPGDHNDNHLVNGETKCFHSGRFYNESEQWR-SAQDSCQMCACLRGQSSCEVIKCPALKCKSTEQLLQRDGECCPSCVPKKEAADYSAQSSPATNATDLLQQRRGCRLGEQFHPAGASWHPFLPPNGFDTCTTCSCDPLTLEIRCPRLVCPPLQCSEKLAYRPDKKACCKICPEGKQSSSNGHKTTPNNPNVLQDQAMQRSPSHSAEEVLANGGCKVVNKVYENGQEWHPILMSHGEQKCIKCRCKDSKVNCDRKRCSRSTCQQQTRVTSKRRLFEKPDAAAPAIDECCSTQCRRSRRHHKRQPHHQQRSSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** : . ..* : ..: : . : * ** . * .**:.*** ***** *: * * ** .:*.*:*:* :** * :* ***:**:*** : . : : : : * : . :.: . . ** **. : :..* :*. *:.** : * * * *. : . :**:*: **: * *. ::*:* : : . * : * : ** :* **::* . * ** :::: * .: . :*: *::.*:. . : .::::: : .:: : .. : : .. *: . :. ::: : *:* : :: . :*.*.* * **: :*::*. * . :: * * . * :*** *:: . .: . : : .:*.. . : * * : .: . * .** :*:.* .. : .*: . *: * . .. *.* **:*:* .*:****: : *: .: . . . ::** * *. :*.. .: * :* . . * : :* . : :**::: . . . .**..*. .. :* . : * * * : *: : **. .* . * : :*** * *: : .. . : ... :..*: ***.:** * .*:.*:*. * *::* :: ** * *:. : .* . *** ** . . : ** . .: *:. : : :.: *** : ** .**.* * . :*:*. * . . . . .* . : .:. . ", "identical_positions": 185, "similar_positions": 273, "identity": "16.99%" }, { "cls_id": "homologset.agr.FB:FBgn0003464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAS0-1", "uniprot_id": "A0A0G2KAS0_RAT", "id": "A0A0G2KAS0-1", "name": "Calpain-15", "aln": "-----------------------------------------MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQH------PRPRA----------------RSHTHSPGSMATVG---EWSCARCTFLNPAGQRQCSICEAP---------------------------------RHKPDLDQILRLS-VEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLL---------------------------------------PIINGVLPKPPTILV-------------------EPKGNSKEETGPVRTAGLVATEPARGHPEKEEE--------EKEQEDDGERADPGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTG-FHVVPPPS------------------------------------------------QPALPGEGAEAESPSTSQGPTSTDQEPPRVPLFSPFSPTLQNNPVPRSRREVPPQLQPPVPEGAQSSASTSS-------KGPQQGPGRAAAGASRLAELLSGKELLPGKRLSV-----------------LEEEAPESSPARCES--------CSDVIDLAGDVVR---------------------------------------------------YTPASPSSPDFTTWSCARCTLRNPTTASRCSVCGGSKLHGFQEHSEP------PTHCPDCGADKPG--PCVGSCGRA-----PSAHKAARLLPD------------------------------------------------------------------------------------------------------------------------------------------RPGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGATPLR------------RRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQR--VKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSST-NPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPSSEPQSPPAGKLLAPLSTPPTASSPSAGVPRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLG8-1", "uniprot_id": "CAN15_MOUSE", "id": "Q9JLG8-1", "name": "Calpain-15", "aln": "---------------------------------------------------------------------------------------------------------------------------------MATVG---EWSCARCTFLNPAGQRQCSICEAP---------------------------------RHKPDLDQILRLS-VEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLL---------------------------------------PIINGVLPKPPTILV-------------------EPKGSGKEEAGPVRTAGLVATEPARGRPEGEEEREERGEEEEKEQEGEGERAEPGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTG-FHVVPAPS------------------------------------------------QPVLPGEGAEADSPSTSQGPTSTDQEPPRVPLFSPFSPTLQNNPVPRSRREVPPQLQPPVPEAVQSSASTSS-------KGPQQGPGRAAAGASRLAELLSGKELLPGKRLSV-----------------LEEEVPESSPARCES--------CSDVIDLAGDIVR---------------------------------------------------YTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEP------PTHCPDCGANKPG--PCVGSCGRA-----PSAHKAVRLLPD------------------------------------------------------------------------------------------------------------------------------------------RPGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGATPLR------------RRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQR--VKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSST-NPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTAGGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQ-----------------------------------ASSPSAGVPRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75808-1", "uniprot_id": "CAN15_HUMAN", "id": "O75808-1", "name": "Calpain-15", "aln": "---------------------------------------------------------------------------------------------------------------------------------MATVG---EWSCVRCTFLNPAGQRQCSICEAP---------------------------------RHKPDLNHILRLS-VEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFL---------------------------------------PVLNGVLPKPPAILG-------------------EPKGSCQEEAGPVRTAGLVATEPARGQCEDKDE------EEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAG-FHVVPAAP------------------------------------------------PPGLPGEGAEANPPATSQGP-AAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAGC-------RGAPQGSG--WAGASRLAELLSG------KRLSV-----------------LEEEATEGGTSRVEAGSST---SGSDIIDLAGDTVR---------------------------------------------------YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEP------PTHCPDCGADKPS--PCGRSCGRV-----SSAQKAARVLPE------------------------------------------------------------------------------------------------------------------------------------------RPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAPLR------------RRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQR--VRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQLSST-NPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAP----------------------------------QASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLF5-1", "uniprot_id": "A0A8M2BLF5_DANRE", "id": "A0A8M2BLF5-1", "name": "", "aln": "-----------------------------------------MGSSASSLTTDRESDHGFGTAPFPAAAP--MGWLRTSHSSPVWGTTFITRQQQQHQQPIPHRE----------------RSHSHSPGSMEAVVRNSDWSCGRCTFLNSSGSMRCSICEAP---------------------------------RQKPDLNHILRLSSAEEPRWSCPRCTLTNHHGLGSCSVCGAAPV-TPNGPLP---------------------------------------PKQ--TPPTPIDLAS-------------------SPEPKGQVANGESQCIESNGEVPMSGQGS--------------------------SEWACPRCTLVNTPVALSCSACGGPRKLSLPKIPPEALVVPEVRTPVAGFPTQTAGA------------------------------------------------SAPLLIDLTEDSPP---QAP-SETPSPPPVPFLPPSLSSLQNNPVPRSRREVPPPGRPPNPGPSPTSPSSCPP------TKPKPLPPSGNYPVKRLSVLEEEEPNNPTPPVTSPPSWKCPGCS-------APTAPPSSSAGRCDACRGSRPGSGGDVIDVLGESVR---------------------------------------------------FTPASPSSPDFSSWACSKCTLRNPTGAGHCTACGSSKLHGFSE----------PSSCSSCSRKQPHSHPRAFTSTSS-----SSSISSPSAQDK------------------------------------------------------------------------------------------------------------------------------------------SVCQWTCPACTLLNEGRMKHCAACHTPQQYLNLRKTGKPLK------------RRESMHVEARRRTDEGEAKELWENIVSFCRENAVNFVDDSFPPGPRSVGFPENDSVQQR--IKKWLRPHEINCNNFKDRGVKWSVFRTPRPSDILQGLLGNCWFLSALAVLAERPELVERVMITRSICQEGAYQVRLCKDGMWTTVLVDDMLPCDEYGFLLFSQAQRRQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLMLQVSST-NPREEPIDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAVYESLGLRPRHAYSILDVRDVQGYRLLRLRNPWGRFSWNGSWSDEWSDWPQHLRHELMAHGSSEGVFWMEYGDFIKYFDSVDICKIHPDWQEVRLQGCFPCRASKPVTVTALTVLERTALEFALFQEGSRRSDTADSHLLDLCIMVFRASFSNGNKLVLGRLLAHSKRAVKKFVGCDVMLEPGEYAVVCCAFNHWQMDLSGASTP-----------------------------------VSSPTN-ARRPSQDFPGYILAIYSSRQVMVEQVEATSTTLADAIILLTENKGERHEGREGMTCYYLTHGWAGLIVVVENRHPKYYLHVSCDCTDSFNVVSTRGSLKTIDSVPPLHRQVLVVLSQLEGNAGFSITHRLAHRKAAQASLGDWTSSKATHSPQLTPDTDGLHRPRPL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27398-1", "uniprot_id": "CAND_DROME", "id": "P27398-1", "name": "Calpain-D", "aln": "MGTISSVLQWSCTKCNTINPTESLKCFNCGTVRKVFPQQQQQQHRSSSITASWTADDALEQEQAEKGQERDKEKGRAAVARSEYKHVYKSLLRGCLKRPQRNSQNLPANCVDCEDTRKYIKSSIELYRHFSNPALNRRWVCHACGTDNSSVTWHCLICDTVSYLAPIYKDAIAADRGQDLAGSLGNRGELLAADHSHPHHHHHYLHQELEEQHQHQLHSQHLHKRHLKGRSASGSGSGPGSGSGLRRTQSLSTAIDKSASGRSCHICYANNQSKDIFNLPQIKPAPQLTGIPPVAACSNSRFAIANDTFCRRKQNNNNKNQNHKVVRESGAKRKYNFTITTLSRSAAKDAGHG-QMKPLRQVVNLNLNLQQEPQQKSPANPQQLQRKTQREPAAVSMNPTQFTIPRNG-VFIAVNEWSEPMASSSSVSSSSNHHHHHHSNSNSNSSGNSNIINNNSSSSSGSNKLYENECVALAQQQLRAAAAQAAQAAATAVAIASSPSAKAMAEPAPTATMPIYAQVNKQHKLKKKQQIASESQTNNNTGSGEIADAVSESLTAGLGTSTDGSGEASESESQVEEHSIYAKVWKGPRKATESKIMHDPGSSSRLSGAASAAAGTASAGAIAAAVGAAAASRHDNKTQLGNGSRSKMWICIKCSYAYNRLWLQTCEMCEAKAEQQQQQLQLQQQQQQQQQHHHHHLQQQQAEAPRDEPWTCKKCTLVNYSTAMACVVCGGSKLKSISSIEDMTLRKGEFWTCSHCTLKNSLHSPVCSACKSHRQPQLSMAMEAVRERPDGQSYEEQDAAAVGGGGGSAHQSGANEVKAPTALNLPLTSVALPMPMLQLPTSTAAGLRGSRSPSPRMQLLPSLQQQRNSSSSGAIPKRHSTGGSIVPRNISIAGLANYNLQQGQGVGSASVVSASGAGSGAGAVGASTSTKKWQCPACTYDNCAASVVCDICSSPRGLASAVLGEALGRKSVRVALTPADIRQESKLMENLRQLEETEALTKWQNIIQYCRDNSELFVDDSFPPAPKSLYYNPASGAGEGNPVVQWRRPHEINCDGG--AYPPWAVFRTPLPSDICQGVLGNCWLLSALAVLAEREDLVKEVLVTKEICGQGAYQVRLCKDGKWTTVLVDDLLPCDKRGHLVYSQAKRKQLWVPLIEKAVAKIHGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPMPSEDELDKDLIWAQLLSSRCVRFLMGASCGGGNMKVDEEEYQQKGLRPRHAYSVLDVKDIQGHRLLKLRNPWGHYSWRGDWSDDSSLWTDDLRDALMPHGASEGVFWISFEDVLNYFDCIDICKVRSGWNEVRLQGTLQPLCS--ISCVLLTVLEPTEAEFTLFQEGQRNSEKSQRSQLDLCVVIFRTRSPAAP--EIGRLVEHSKRQVRGFVGCHKMLERDIYLLVCLAFNHWHTG--------------------------------------------------IEDPHQYPQCILAIHSSKRLLVEQISPSPHLLADAIISLTLTKGQRHEGREGMTAYYLTKGWAGLVVMVENRHENKWIHVKCDCQESYNVVSTRGELKTVDSVPPLQRQVIIVLTQLEGSGGFSIAHRLTHRLANSRGLHDWGPPGATHCPPIEN-VHGLHAPRLIT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * *.: :* **:: : :*. .: . ** : :. : . ...* . ... : * * . . : . * : . . .. * ... ..:.. .* ::::*: :.* * * . .. . . : . ..* : * . * . :::: :.::::.. :. ..: . . .:: : .... : * *: * ...:* .*:* :*** * : * * .** ***:.:.. *. * .:. * :. . : .: . :* ***** * * * :*: : *:** :* *: :* ** *:**: :**:* ********.* *: : ... : : :* **:****. *:**:* **** **:*****:********** :**:.*::*:.:* :*********** ********:****: * *::***:*:****.*****:**:**.* ** :*****************: ** ** * *: :*.*****::***: . ***************: *:. *********:***:*:** ***:******::**.*.***: . *. .** **.**:******:.: *.:.***.:****::..*:*.*:** : .. : . ***** : **:*****.*.*: : ****:::**: . :***: **** *: **.*. *** . * :** ***** . . : * :**::**: ::** :.. . ****** ** .:*:*********.****:*****:*:***** : ::**.*** :*:*******.*:* ******:***:::*:****..****:***:** * . * ** .. .**.* : . *** ** : ", "identical_positions": 395, "similar_positions": 271, "identity": "23.9%" }, { "cls_id": "homologset.agr.FB:FBgn0003475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZR0-1", "uniprot_id": "A0A0G2JZR0_RAT", "id": "A0A0G2JZR0-1", "name": "", "aln": "--------------------------------------------------MAQPSSPGG-----------EGPQL-----GATGDPRDALSLEEILRLYNQPINEEQAWAVCFQCCGSLRAAA-RRQPHR----RVRSA-AQIRVWRDGAVTLA-------------------------------------------PAADEEGEPPPASGKLGYSHCTETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDQMANTSEAD-G-------SNDEGYEAADEGP--DEEDGERRSSAAIRSYQDVMKICAAHLPTESEAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKS-DDCSTDLEDLKNADWARFWVQVMRDLRNGVKLKKVQQRQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLRKSAHEIILDFIRSRPPLNPASARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAVRPLSMSHSFDLSDVT-------TPESPKNVGKS--SVVNGDLTSQTKENGLGAAQPGPAQPK--RLLKAPTLAELDSSDSEEE-TLHKSTSSSSASPSLYEDPVLEAMCSKKKPPKFLPISSTPQP----ERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLVPRITSVWPRTPFRPLFSAIQTASLLSSHPFEAAMFGVAGAMYYLFERAFTSRWKPSKEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDVYTALKKGKLCFCCRTRRFSFF-TWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQR---GESCSRSEKPSTGHHRPL----------RSITR-FSSKSKSVDKSD--EELQFPKEFMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSAGPSEYCPSERTINEI--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52KF3-1", "uniprot_id": "SPIR1_MOUSE", "id": "Q52KF3-1", "name": "Protein spire homolog 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANTVEAD-G-------SKDEGYEAADEGP--EDEDGEKRSISAIRSYQDVMKICAAHLPTESEAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKG-DESSTDLEDLKNADWARFWVQVMRDLRNGVKLKKVQQRQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDVPPRLKKSAHEVILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL-VRPLSMSHSFDLSDVT-------TPESPKNVGES--SMVNGGLTSQTKENGLSAAQQGSAQRK--RLLKAPTLAELDSSDSEEEKSLHKSTSSSSASPSLYEDPVLEAMCSRKKPPKFLPISSTPQP----ERRQPPQRRHSIEKETPTNVRQFLPPSRQSSR----------------------------------------------------------SLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDVYTALKKGKLCFCCRTRRFSFF-TWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQR---GESCSRSEKPSTSHHRPL----------RSIAR-FSTKSRSVDKSD--EELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSAGPSEYCPSERTINEI--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08AE8-1", "uniprot_id": "SPIR1_HUMAN", "id": "Q08AE8-1", "name": "Protein spire homolog 1", "aln": "--------------------------------------------------MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRH----RVRSA-AQIRVWRDGAVTLA-------------------------------------------PAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEAD-G-------SNDEGYEAAEEGL--GDED-EKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKS-DESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVT-------TPESTKNLVES--SMVNGGLTSQTKENGLSTSQQVPAQRK--KLLRAPTLAELDSSESEEE-TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQP----ERRQPPQRRHSIEKETPTNVRQFLPPSRQSSR----------------------------------------------------------SLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFF-TWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQR---GESSMRSEKPSTAHHRPL----------RSIAR-FSSKSKSMDKSD--EELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYM3-1", "uniprot_id": "SPIR1_DANRE", "id": "Q1LYM3-1", "name": "Protein spire homolog 1", "aln": "-----------------------------------------------MTDGGMLISPSALQDP------GDGARPEDIAMDCTDG-EEELCLEEILTLYSQPINEEQAWAVCYQCCRWLTQKHRRKETGVSPPGRIAGP-GDVRIRKDGNVKLY-------------------------------------------QPSNPDKHTPPSS---------SIEIIESLGIMIYKALDYGLKEHEERELSPPLEQLIDLMTNMADTETD-------CPDEGYEATEEED--EGEE-ENAEVSNVRGYRDIISLCLSHLPSPSDAPNHYQAVCRALYAETKELRTFLEKIKSAKENLRKMEG--ET-EEPVRDLNELQNADWARFWVQVMRDLRHGVKLKKVQERQYNPLAIEYQLTPYEMLMDDIRSKRYKLRKVMVNGDIPPRLKKSAHEIILEFIRSRPPLNPVSARKLKPHAPQPPTLHERILEEIRSERKLRPVSPDMIRRSRLGAGKSISTPQDLFRSSD-------IPDGPRKLAISTLSLANGTSPARSPVNGVAGGHS-LSQRK--RLLKAPTLAELDSSDSEEEQSTRKSDSSSSISTSLVEDTSPESVMGKKPPPQFLPISSTPQP----DKRIAPQRRHSIEKEAPTNIRHFLPPSRQNSKSLAHALGSG-------------------------------------------------HAEEFCFPVECLTLTVEEVMHIRQVLVKAELEKFQQYKDIYNALKKGKLCFSCRSKKFSLF-TWSYTCQFCKRPVCSQCCKKMKLPSKPHASLPISSLGPSILPKKEPGASSAPTDKTSSTSSHKK----------NSLQRSLSRSSKHGDRSSSKDELELPEQFTEDWSTMEVCVDCKKFINDIISNSRR--NLSTKRARLHRRTHSVYSSSTSSSNYKPTERTIKEV--------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V870-1", "uniprot_id": "G3V870_RAT", "id": "G3V870-1", "name": "", "aln": "----------------------------------------------------MARAGGG------------GAAAPERAGGAARPEPWELSLEEVLKVYEQPINEEQAWAVCFQGCRGLRG------EPGGV-RRIRDT-ADILLRRDGSVGAR------------------------------------------LEPEPSTMVVPPAN--------SEAQMVQSLGFAIYRALDWGLDENEERELSPQLERLIDLMANS-DCEDS-SCG---AADEGYGGP------EEEEEAEGGPRAVRTFAQAMRLCASRLTDPHGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLGEDEPRVEKPLAELDHLGHTDWARLWVQLMRELRHGVKLKKVQEKEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPVPQKQRTLHEKILEEIKQERRLRPVGAEHLGARGFGSLPCILNACSGDIKSTSCINLSVTDAGSGSQRPRPRVLLKAPTLAEMEEMSTPEEEESP---------CGEVALKRDRSFSEHDLAQLRSEMGSGLQSATQPPGGTEPPRVRAGSMHSWRPSTRDQG----LCSVSGQSQPHP-----SNLSSADGPEASA-PDARH-----------------------------------------------------LWL-EFSHPVESLALTVEEVVDVRRVLVKAEMEKFLQDKELFSSLKRGKICCCCRTK-FPLF-SWPPTCLFCKRAVCTSCSVKMKMPSKKHGHIPVYTLGFESLQR-------VPTTKASPALRRDA----------FQCLQGPKWRS---------VEEEFPHIYAHGCVLKDVCSDCTSFVADVVCSSRKSVDVLNATPRRSRQTQSLYVPNTRTLNFQ-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1S6-1", "uniprot_id": "SPIR2_MOUSE", "id": "Q8K1S6-1", "name": "Protein spire homolog 2", "aln": "----------------------------------------------------MARAGGG------------GAAAPERAGGAARPEPWELSLEEVLKVYEQPINEEQAWAVCFQGCRGLRG------EPGGV-RRIRDT-ADILLRRDGSVGAR------------------------------------------LEPEPTTMVVPPAS--------SEAQMVQSLGFAIYRALDWGLDENEERELSPQLERLIDLMANS-DCEDS-SCG---AADEGYVGP------EEEEEAEGGPRAVRTFAQAMRLCALRLTDPHGAQAHYQAVCRALFVETLELRAFLARVREAKEMLKKLGEEEPR-EKPLAELDHLGHTDWARLWVQLMRELRHGVKLKKVQEKEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERQLRPVPQKQRTLHEKILEEIKQERRLRPVGAQHLGGRGFGSLPCILNACSGDIKSTSCINLSVTDTGSGSQRPRPRVLLKAPTLAEMEEMNTSEEEESP---------CGEVALKRDRSFSEHDLAQLRSEMASGLQSAAQPPGGTEPPRARAGSMHSWRPSSRDQG----FCPVSGQSQPLPSSALPSSLSSVDGPEAAS-PDTRH-----------------------------------------------------LWL-EFSHPVESLALTVEEVVDVRRVLVKAEMERFLQDKELFSSLKRGKICCCCRAK-FPLF-SWPPTCLFCKRAVCTSCSVKMKMPSKKYGHIPVYTLGFESLQR-------VPTTKATPTLRRDA----------FQSLQGPKWRS---------VEEEFPHIYAHGCVLKDVCSDCTSFVADVVCSSRKSVDVLNATPRRSRQTQSLYIPNTRTLNFQ-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWL2-1", "uniprot_id": "SPIR2_HUMAN", "id": "Q8WWL2-1", "name": "Protein spire homolog 2", "aln": "----------------------------------------------------MARAGSC------------GGAA----AGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRG------SPG---RRLRDT-GDLLLRGDGSVGAREP----------------------------------------EAAEPATMVVPLAS--------SEAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMANN-DSEDS-GCG---AADEGYGGP------EEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESP---------CGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQG----TCPASVSDPSHP--LLSNRGSSGDRPEASMTPDAKH-----------------------------------------------------LWL-EFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAK-FPLF-SWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQR-------VSAAKTAPIQRRDI----------FQSLQGPQWQS---------VEEAFPHIYSHGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFK-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3H9-1", "uniprot_id": "SPIR2_DANRE", "id": "Q5U3H9-1", "name": "Protein spire homolog 2", "aln": "----------------------------------------------------MARSADR------------SAED-----GDSRAGIRELSLEEVLKSYEQPINEEQAWAVCFQCCGDLRAPRPQPHPRRPE-LQIRDP-ASIILHRDGRVTAL------------------------------------------LQSCDDSNAGCESA--------ADGKLVQSLGVAIYRALDWGLDDSEERELSPQLEQLIEFMVGGPDCGQSKHCGSNAAKDEGYSGQDEEEEEEEEEEEEGAGRGIHTVQQVMTMCASRLANPVLAPEHYQAVCRALFLETLELQTFLSRIRDAKEMLKKIRKEEPQ-EDSAAELDALQHTDWARLWVQLMKELRQGVKLKKVEEQPFNPLPTEFSLTPFEMLMQDIRLRKYKLRKVVVDGNIPTCVKRNAHELILDFIRSRPPLKPVSERSLPPPPQRPQSLHDRVLAEIRQDHKLRPVELP-SSKRSFGSLPCLAHTCQCDIKSTSCIDLSVTGAGSRPS-SRIRVLLKAPTLAEMEEMNIFEDEDSPDGVDMRRVESSPTPLKRDRSFSEHDLDELRGEMMSDSPQHSG-VAALRAERPRSHTLTGVYQASFPGF----ERRSASTCRSLS----SDDRSSDPGGDSASHGLSRH-----------------------------------------------------QWMEEFCHPVETLALTVDGVINVRRILVKAEMEKYMQNKELFSNLKKGK--------------------------VCVSLSYMIDIS---------------------------PTAQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1K1-1", "uniprot_id": "SPIR_DROME", "id": "Q9U1K1-1", "name": "Protein spire", "aln": "MTEHQAEEQADTPPTKVKATPTPTPSGKFKDAKEDAFLSTSPDSANGDAQHKLPADQLAMSSSAHPQQAGQARPLILQAFHRCSSPEQCVTLHDILDSFKAPLSEDQAWALIHQFAGLYHQVAVQAHTCAADYEAALPTGFELHFHRDGSVHFSGPDQLTPKEQLQQEQIPLPPQHDVIVDQPDHSASSSGDSSVINRAFDNSNHHHHHQHHHPPLVVSHRKIISELAEIVYTALDYNLPEDEECQVSQELENLFNFMTADETDDDC--------IDEGIDEGDK----RWDDESEEERNDTKELEHIIETCRNHIKT-TLPENHYRAVCRALVTETIELRVFLQQVLNNEAGAEKLIKASESSATTQQELAKLGFNDWARFWVQVIDELRRGVRLKKSN---HERTPIEYELTPYEILMGDIRAKKYQLRKVMVNGDIPPRVKKDAHAMILEFIRSRPPLKKASDRQLGPPRMCEPSPREQLMESIRKGKELKQITPPEAPTLRERVLPSANSTLSRSRQRLIKVDFSKFQDDDLFYDENSISSSHSTAATHQHHPHFAEMHRCSQPKMPPYPFGGYMVPSQARQDCRETASLMRPRRTMEPAKQVPPPEEPSFTKDEYHKFYDTALESYDLATQCESRRASLRRHTIVGCQSNLDETHSMPPTRPESRQSDDVSKETPKRSPAEQTHPSDEGSSTSSLG-------------------PWNKSFMDKQTWMERGDDRLSVTLAEIVHIRSVMTKAELEGLPMDVRVKEDVEKRRVCFLCLRTRFSFFGPWGIQCKLCQRTVCAKCYTKMRIPSEHFRNVPLVLISPSLLSSPASSSTPSPSHHAQQAHSSSTGNIMDDQFPKSLIERLLRSESDRKTRSTVGSAPSSPKHQRSNMSTPGISVGPGASSSSAAATGQAVEALHDQATMSSSYSAAMRPSGVHQQQKQHYNNAMSRSMEGPRSLPVHSPAYRPLSNNSTLERKSRFSRGFNLFSSGSHLAQTQEQKENLRGEQVTVCNDCQGLVNEITSSVKQKRSSARNRTIQNLTLDLTPVWK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *** :: . : . : * :: . **:****** ** **:.** :: . : .*: :* * ****:***:: :**.**:*** : .: . *:.***:*:** *** :.* ****:*:*::*. :::.** :**:********: .* * * * : ::::: .*: :.*: : . . :. :. . . . . ... : . : . : : *::*: ::.:* ::.***:* : ::: : ** . : :. : : ", "identical_positions": 81, "similar_positions": 102, "identity": "7.68%" }, { "cls_id": "homologset.agr.FB:FBgn0003479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08297-1", "uniprot_id": "RAD51_MOUSE", "id": "Q08297-1", "name": "DNA repair protein RAD51 homolog 1", "aln": "------------------------------------------------------MAMQMQLEASADTS---VEEE-SFGPQPISRLEQCGINANDVKKLEEAGYHTVEAVAYAPKKELINIKGISEAKADKILTEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARGFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06609-1", "uniprot_id": "RAD51_HUMAN", "id": "Q06609-1", "name": "DNA repair protein RAD51 homolog 1", "aln": "------------------------------------------------------MAMQMQLEANADTS---VEEE-SFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I2J2-1", "uniprot_id": "A0AC58I2J2_DANRE", "id": "A0AC58I2J2-1", "name": "DNA repair protein RAD51 homolog", "aln": "-----------------------------------------------MCYEGVNMAMRNASRVEVEAE---VEEEENFGPQPVSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEIIQISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27297-1", "uniprot_id": "RAD51_DROME", "id": "Q27297-1", "name": "DNA repair protein Rad51 homolog", "aln": "--------------------------------------------------------MEKLTNVQAQQE---EEEE--EGPLSVTKLIGGSITAKDIKLLQQASLHTVESVANATKKQLMAIPGLGGGKVEQIITEANKLVPLGFLSARTFYQMRADVVQLSTGSKELDKLLGGGIETGSITEIFGEFRCGKTQLCHTLAVTCQLPISQKGGEGKCMYIDTENTFRPERLAAIAQRYKLNESEVLDNVAFTRAHNSDQQTKLIQMAAGMLFESRYALLIVDSAMALYRSDYIGRGELAARQNHLGLFLRMLQRLADEFGVAVVITNQVTASLDGAPGMFDA--KKPIGGHIMAHSSTTRLYLRKGKGETRICKIYDSPCLPESEAMFAILPDGIGDARES--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25454-1", "uniprot_id": "RAD51_YEAST", "id": "P25454-1", "name": "DNA repair protein RAD51", "aln": "MSQVQEQHISESQLQYGNGSLMSTVPADLSQSVVDGNGNGSSEDIEATNGSGDGGGLQEQAEAQGEMEDEAYDEAALGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVPMGFVTAADFHMRRSELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQIPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQRFGLDPDDALNNVAYARAYNADHQLRLLDAAAQMMSESRFSLIVVDSVMALYRTDFSGRGELSARQMHLAKFMRALQRLADQFGVAVVVTNQVVAQVDGGM-AFNPDPKKPIGGNIMAHSSTTRLGFKKGKGCQRLCKVVDSPCLPEAECVFAIYEDGVGDPREEDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ... : . :* . .: :* .*. *:* *.:.. **.*:** *.:*:*: * *:. .*.:::: ** ::**:** :* *: *:::: ::****:**.** **:*******:***** **:*:*********:*:. *****.:*****.**** ** ::*:*: * .:.*:***::*..*:*:* :*: *: *: ***::*::***. ****:*: *****:*** **. *:* * ****:******:****.*.:**. * . ******:*:**:***** ::**:* *:**: *******:*.:*** **:**.:: ", "identical_positions": 169, "similar_positions": 106, "identity": "42.14%" }, { "cls_id": "homologset.agr.FB:FBgn0003480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CXE6-1", "uniprot_id": "XRCC3_MOUSE", "id": "Q9CXE6-1", "name": "DNA repair protein XRCC3", "aln": "--------MDLDQLDLNPRIT--AAVKRGRLKSVKEILCYSGP--------DLQRLTGLPSHDVQCLLRAASLHLRGSRVLSALHLFQQKESFPEQHQRLSLGCPVLDQFLGGGLPLEGITGLAGCSSAGKTQLALQLCLAVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIAQQRRLRTDAPEELIEKIRFSNHIFIEHAADVDTLLECVSKKVPILLSR--GMARLVVVDSIAAPFRCEF---HLQASAIRAKLLLSLGATLRRLSSTFRSPVLCINQVTDM-----------------------------------------------------------------------------------------VEDQQSVSRSLGASEERLSPALGITWANQLLMRLMVDRTHEDDVTT-------------GLPRSPVRTLRVLFAPHLPLSSCCYTVSGEGIRGMPGTQSY---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5N4-1", "uniprot_id": "D4A5N4_RAT", "id": "D4A5N4-1", "name": "DNA repair protein", "aln": "--------MDLDQLDLNPRIT--AAIKRGRLKSVKEVLCYSGP--------DLQRLTSLPSHDVQLLLRAAALHLRGSRVLTALHLFQQRESFPEQHQRLSLGCPVLDQFLGGGLPLEGITGLAGRSSAGKTQLALQLCLAVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIEQLQELRTDVPGEVTQKIRFGNHIFIEHAADVDTLMECVSKRVPILLSR--GMARLVVVDSIAAPFRCEF---HLQASAVRAKHLHSLGAALQRLSSTFRSPVLCINQVTEM-----------------------------------------------------------------------------------------VEDQE----SAGAWEERLSPALGITWANQLLMQLMVDRIHEDSVTT-------------GLPRSPARTLRVLFAPHLPLSSCCYTVSGEGVRGMAGTESC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43542-1", "uniprot_id": "XRCC3_HUMAN", "id": "O43542-1", "name": "DNA repair protein XRCC3", "aln": "--------MDLDLLDLNPRII--AAIKKAKLKSVKEVLHFSGP--------DLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSR--GMARLVVIDSVAAPFRCEF---DSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEA-----------------------------------------------------------------------------------------MEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAAL-------------GCP---ARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77135-1", "uniprot_id": "O77135_DROME", "id": "O77135-1", "name": "", "aln": "--------MTNFLDQLPKHIR--EIAEQVNVLAPEEVLTTPKVRFLDTRQQSLHTIVRKCTPDDVRVLKDAAAKWLAEMPQSADSLFKP--LVNVRWSRVSFGCSALDRCTGGGVVTRGITELCGAAGVGKTQLLLQLSLCVQLPRELGGLGKGVAYICTESSFPARRLLQMSKACEKRHPEM------ELNFLGNIFVENHIEAEPLLACVINRIPRLMQQ--HGIGLIIIDSVAAIFR------LYNDYLERARHMRRLADALLSYADKYNCAVVCVNQVATR-----------------------------------------------------------------------------------------DGQDE-------------IPCLGLQWAHLGRTRLRVSRVP-KQHRM-------------GDQLITVRKLEILYSPETPNDFAEFLITAEGVVNVPEPSVPSPPAKMRRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25301-1", "uniprot_id": "RAD57_YEAST", "id": "P25301-1", "name": "DNA repair protein RAD57", "aln": "MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVCVVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTTADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITTEGDLPTQRLESMLSSRPAYEKLG--------ITQSNIFTVSCNDLINQEHIINVQLPILLERSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGDKPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYMLIERVMSTVNDRNYDFFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTWSNHVSTRILLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAYQITKRGIETA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* .: .. : : : :. . ::: : . .: . .:* **: *** : * :..**:** :**.*.**:.. *** .** **. :* :** .: . .:** : : ::* *:.: *:::**:: :* . . . : :. * : : .*: *** .. * **: *:: :: .: . . *.:.:: :. . : :: .*: ", "identical_positions": 46, "similar_positions": 90, "identity": "9.52%" }, { "cls_id": "homologset.agr.FB:FBgn0003483", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MHU3-1", "uniprot_id": "TDRD9_RAT", "id": "Q3MHU3-1", "name": "ATP-dependent RNA helicase TDRD9", "aln": "MLRKLTVDQINDWFTIGKTVTNVELLGLPPAFPAEAPREEVQRSEEVPSEAPTAQAQDPVKATALARPASAFGRSLSQRSSEVEYINKYRQLEAQELDIYGQDQPPSGPGLRSPLAKISNVACIPETTYKYPDLPINRCKEEVISLIESNSVVIIHGATGSGKSTQLPQYVLDHYTQRSAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQVGLEK-TATEDTRLIYMTTGVLLQKIVSAKSLMEFTHVFIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVILMSATINCKQFADYFAVPVQNKMNPAYVFEVEGKPHTIEQYYLNDLGHIYHS--GLPPYRLEEPVITKDVYEVAVSLIQMFDDLDMKESGNKTWSGAQFVSERSSVLVFLPGLGEINYMHELLTNMIHKR----LQVYPLHSSVTLEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCDQRKGRAGRVSKGYCYRLIHRDFWDSAIPDHVVPEMLRCPLGSTVLKVKLLDMGEPRALLATALSPPSLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVSQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFTMP--FRQHLDGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGELRHPKDELDWGRLNYIQIKRIREVAELYEELKNRISQFNMFVDPRHPVLDQEYPYKQRFILQVVLAGAFYPNYFTFGQP----DEEMAVRELAGRDPKTTVVLKHIPP--YGFLYYKQLQSLFRQCGQVKS-----IVFDGAKAFVEFSRN-PTERFKTLPAVNLAVKMSQLKVSLELSIHAAEEIEGKVQGGSVSKLRNTRVNVDFQKQTVDPMQVSFNTLDRPRTVADLLLTVDVTEVVEVGHFWG--YRIDERNAELLRQLTAEINRLELVPLPIHPHPDLVCLAPFTDYN-KESYFRAQILYVSGNSAEVFFVDYGNRSHVDLDLLREIPCQLLELP--FQALEFKICKMRPSAKSLICG-EHWSGGANGRFAALVSGCPLLVKVFSIVHSVLHVDVYRYSGAQDAVNIRDVLIREGYAELAEESYESKQSYEVLKGFFAKSVD-----TMPDGSVSSPMKDDEKHLIQILLESFASNRLGAPNCKAVLHGPFNPYELKCHSLTRISKFRCVWIEKESINSVVISDSPADLHQRMLVAASLSVNETGSTMLLRETSLMPHIPGLPALLSMLFAPVMELRVDREGKCYTGVLCGLGWNSTTEAPILPEHDIELAFDVCFNVEDIVEIN-------------------------------ILRAAINKLACDG----------------PHGPKYLGPERIAQLQENARQKLLGLFCRLKPREKITPQWHEKPYEWNQVDPRLVIEQAEREGGPGKSTCLYQLHTPVVLSP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BI7-1", "uniprot_id": "TDRD9_MOUSE", "id": "Q14BI7-1", "name": "ATP-dependent RNA helicase TDRD9", "aln": "MLRKLTVDQINDWFTIGKTVTNVELLGLPPAFPAEAPREEVQRSEEVPNEDPTAQAQVPVKATAPARPASTSGRSLSQRSSEMEYINKYRQLEEQELDIYGQDQPPSGPGLRSPLAKLSNVACIPETTYKYPDLPINRCKEEVISLIESNSVVIIHGATGSGKSTQLPQYVLDHYTQRSAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQVGLEK-IATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIFIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATINCKQFADYFAVPVQNKMNPAYVFEVEGKPHAIEEYYLNDLGHIYHS--GLP-YRLEEPVITKDVYEVAVSLIQMFDDLDMKESGNKTWSGAQFVSERSSVLVFLPGLGEINYMHELLTNMIHKR----LQVYPLHSSVTLEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCDQRKGRAGRVSKGYCYRLIPRDFWDSAIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPSLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVSQQLGKLVVLGHVFGCLDECLIIAAALSLKNFFTMP--FRQHLDGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGELRRPKDELDWGRLNYIQIKRIREVAELYEELKNRISQFNMFVGPHHPVLDQEYPYKQRFILQVVLAGAFYPNYFTFGQP----DEEMAVRELAGKDPKTTVVLKHIPP--YGFLYYKQLQSLFRQCGQVKS-----IVFDGAKAFVEFSRN-PTERFKTLPAVNLAVKMSQLKVSLELSVHAAEEIEGKVQGGSVSKLRNTRVNVDFQKQTVDPMQVSFNTLDRPRTVADLLLTIDVTEVVEVGHFWG--YRIDERNAELLKQLTAEINRLELVPLPIHPHPDLVCLAPFTDYN-KESYFRAQILYVSGNSAEVFFVDYGNRSHVDLDLLREIPCQFLELP--FQALEFKICKMRPSAKSLICG-EHWSGGAHGRFAALVGGCPLLVKVFSIVHSVLHVDVYRYSGAQDAVNVRDVLIREGYAELAEESYESKQSYEVLKGFFAKSVD-----TMPDGSVSSPLKDDEKHLLRILLESFASNRLGAPNCKAVLHGPFNPYELKCHSLTRISKFRCVWIEKESINSVVISDSPADLHQRMLVAASLSVNETGSTMLLRETSLMPHIPGLPALLSMLFAPVMELRVDREGKCYTGVLCGLGWNSATEAPILPEHDIELAFDVRLNVEDIVEIN-------------------------------ILRAAINKLVCDG----------------PNGSKYLGPERIAQLQENARQKLLGLFCRLKPREKITPQWHEKPYEWNQVDPRLIMEQAEPEGSPGKSTSLYQLHTPVVLSP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDG6-1", "uniprot_id": "TDRD9_HUMAN", "id": "Q8NDG6-1", "name": "ATP-dependent RNA helicase TDRD9", "aln": "MLRKLTIEQINDWFTIGKTVTNVELLGAPPAFPAGAAREEVQRQDVAPGAGP--AAQAPALAQAPARPAAAFERSLSQRSSEVEYINKYRQLEAQELDVCRSVQPTSGPGPRPSLAKLSSVTCIPGTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEK-IATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHS--KLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKR----LQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMP--FRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDSRRPVMDQEYIYKQRFILQVVLAGAFYPNYFTFGQP----DEEMAVRELAGKDPKTTVVLKHIPP--YGFLYYKQLQSLFRQCGQVKS-----IVFDGAKAFVEFSRN-PTERFKTLPAVYMAIKMSQLKVSLELSVHSAEEIEGKVQGMNVSKLRNTRVNVDFQKQTVDPMQVSFNTSDRSQTVTDLLLTIDVTEVVEVGHFWG--YRIDENNSEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFD-KQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELP--FQALEFKICKMRPSAKSLVCG-KHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQQGYAELTEESYESKQSHEVLKGLFSKSVE-----NMTDGSVPFPMKDDEKYLIRILLESFSTNKLGTPNCKAELHGPFNPYELKCHSLTRISKFRCVWIEKESINSVIISDAPEDLHQRMLVAASLSINATGSTMLLRETSLMPHIPGLPALLSMLFAPVIELRIDQNGKYYTGVLCGLGWNPATGASILPEHDMELAFDVQFSVEDVVEVN-------------------------------ILRAAINKLVCDG----------------PNGCKCLGPERVAQLQDIARQKLLGLFCQSKPREKIVPKWHEKPYEWNQVDPKLVMEQADRESSRGKNTFLYQLHKLVVLGT-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4F4-1", "uniprot_id": "TDRD9_DANRE", "id": "B8A4F4-1", "name": "ATP-dependent RNA helicase TDRD9", "aln": "MHQAITSAQIAHWFTVGAQFANIRIT-------NEAKKAEAEDN------------------ATEVRSDKAFSELSSPEKEKSDDGNQRRKR----------AQLPTGPGTSPP----------SLASYEYPILPITKNRQELVSLIENNSVVIIRGATGSGKTTQLPQFILDHYAERNIPCNLVVTQPRKIGATSIARWVARERKCTLGSLVGYQVGLEK-MATEHTKLIYVTTGVLLQKLVSSKTLTEYSHIFIDEVHERSEELDFLLLVVRKLLRSNSRYVKVILMSATINCIEFAEYFGSPIRNQMNPAYVFEVEGAPYAVEEYYLDELKTMLPVGVNLDLTLPQDPYITEEMYNVAVSLIQSFDEMEAKDHRRSEQTGSTTHPERGSVLVFLPGLAEIQYMKEALSKLVRKR----LQVYPLHSTVTLEEQNGVFLVPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLVRQLACDKETNYRCLRITWASKTSCNQRRGRAGRVSKGFCYRLVTRHFWENEIPNFSIPEMLRSPLASTLLKVKLLDMGDPRSVLSTALTPPILGDIERTVLQLKQIGALSVQSNSQRQ--FDGDLTFLGRVLAQLPVDLQLGKLIVLGHVFGCLEECLIIAASLSLKSFFAMP--SLQQLAGYRSKLSFAQNVPSDFIAYVNAFKAWYTSRAKGELRHPKDELEWGKENCIQIKRIREVAELFEDLKKRVSRFNMHISSSSNPTDYTSLHKQRFILQVVIAGALFPNYFSQGEI----DEQLASKELSGNDPKTTILIRNLPP--FAFLCYKQLQSLFRQCGQVKS-----IAFDGSRAYVEFHRS-CVRESGVLHEVLLALLRSRHTPALHLQVHHADEVEFHAKGKPIAHLRYTRVNVDVQSHTVSPVGVLSSSVNPEKLPTSRDFVINITEVIDVGHFWG--FQTDENSVEKQCQLTAALNMRDLRPLSVSLYPNLLCVAPFKDGQQMAKYYRAKVLHILGSNVEVFFVDFGNTTVVPSSSLRELPSDLMTPA--FQAQEFCIARMAPSAQSLILG-DRWSSRARNRFKTLTSGRSAIVSLFSILHGVMRVDLH-ISTETGDVSVADLLVQEGHACHTPESFESQQSHEVLISLYEDMASGRFTPSFASGSLNSRMEED-KQLINQLLLHFCSSGSSAPKCKAVVHGPSSPHKVNFHSMSKVSNFRSVNIERDSINCVMVNENPQDWHERMLVAASVSLSASGSRILLKETSLMPHIHGLPSLVTMLFTPVMELRTNEDRTCFTGALCGLGWNSVSQEAVLPEHDIEIAFDVKFEIEDITEIN-------------------------------ALRGTVNRLVCDG----------------PNGLLNLSQEKISSLQEEARERLIRLFIKTPSRPECTPVYHDKFKKWNLVDRSQQMEIQEKDDGKSK-GVLFQLHPITLLNM-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF26-1", "uniprot_id": "SPNE_DROME", "id": "Q9VF26-1", "name": "Probable ATP-dependent RNA helicase spindle-E", "aln": "-----MDQEVMDFFDFSKELKRVAAAPQGYISSDPRLMATKFKSSEVP--------------NRELIGTDYVSKIVAKEKCLLNGTLLNEQPQGKRIRTLDDLDTDDEGEETEIRRDDEYYKKFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNS---IPPVITTNHRRKHSIEKFYRDQLGSIIWN--EEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQS-YDEALRYGAVLIFLPGIYEIDTMAENLTCMLENDPNIKVSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYD-PLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENG--HDQESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNP-NQMMDDREKAIMLKVIIAGAFYPNYFTRSKESCADTDRNIYQTISGHDPCRTVYFTNFKPAYMGELYTRRIKELFQEVRIPPENMDVTFQEGSQKVFVTFKQDDWIEGSSKYVPVSGRVQSEVYKAVMMRQNRVERPIHIMNPSAFMSYVQQRGIGDVIEGRWIPPTKPLNVELLALPSVFDKTISGSITCIVNCGKFFFQPQSFEECIRNMSEIFNAPQQLRNYVTNASAIAKGMMVLAKRDSYFQRATVIRPENQSNRQPMFYVRFIDYGNCTLLPMQLMRLMPRELTEQYGDLPPRVFECRLAMVQPSSVVSGNNRWSTAANDMLKTVAQCGLIDIEVYSLFNNVAAVLIHMRDGIINDKLVELMLCRR-----SDEDYMSRKDHDFRLRRQESARN------LSTAQRQQINEEYLRSCQLPQDHDLPPPPLEKCKTVVMLKGPNSPLECTMRSITRVGLSKRVNIDHLSVNALLLDADPQDHHDHLIVAHEIAESRNGQTLTARGTTLMPNVQGFGALMVMLFSPTMQLKCNKEGTSYVSVLGGLGCDPDTNEPYFAEHDVLINLDVNILEDDVILINQIRYYIDSVFFNFKEENNPAVSVNERVSIYTQLRSLINRLLCKDRRYIERNMSNADFEWETNPELPLPNEPFGKRAIFPMHSLTELQEEDTGRLVQLRENCSMLHKWRNFEGTLPHMTCKLCNQLLESVPQLRLHLLTILHRDREKQIDYCNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:* .. . .: . . : .. : .: : . *.* ::*::: *: :.****:* **.**:**:**::**. : . *.:******:*.* ***. :.:** . : .:****.: : *.*:*:* ******::::. *:* .::*:.:****** :::****:***:** :***.**::******.. ::::** . *. : . :::*::* ::* : : * *.:. *..**.:* :*::: * .. : . .:**:****: **: * * *: ::.: :.: .* :: *:*..** * **:*****:*******:*****.*******.: . * :.: .**::****:.* ** **.**: * **:: :.*:: :*:. :***** ** .::**.*:*:**.* :*: **:** *.**..*:* **::*** : : : **:**: * ::::**:. : .:*::**::*. *:*.:****.** .:*: * .: : *: . ** :* ..: :: * : :. : *.: :.:: ::*: * ::*: * :::.: . : :: ::*:*::***::****: .: :. : ::*.** *: : :: * . * ::::.**:: . : .. :.:* * :. . * : . . : . : :. . :: :: :. .: : : * . : .:* ::: *:*: :* : :.* : . . .:: :* . *.: * *:*:** : : : :* :: : . * ...*:: * .:** * : ::. :.::*:.:.* * :: . . : :* :. : *.: *::.::. . . :. .. :: : : . : . ::** .* : . :*::::. : * *:: *:*.:::. * * *::::** .:: . .*. : : *:***:: *: :*: ***:*.::*: :.: . :...* *** :. : . :.***: : :** : :*: :* **. :*:* *.. .: * * ... . . * * . * . :*. .: . . : :** .:* ", "identical_positions": 309, "similar_positions": 461, "identity": "20.96%" }, { "cls_id": "homologset.agr.FB:FBgn0003486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00185-1", "uniprot_id": "CP1A1_RAT", "id": "P00185-1", "name": "Cytochrome P450 1A1", "aln": "-MPSVYG-------FPAFTSATELLLAVTTFCLGFWVVRVTRTWVP---KGLKSPPGPWGLPFIGHVLTLGKNPHLS---LTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLIANGQSMTFNPDSGPLWAARRRLAQNALKSFSIASDPTLASSCYLEEHVSKEAEYLISKFQKLMAEVGHFDPFKYLVVSVANVICAICFGRRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPILRYLPNSS---LDAFKDLNKKFYSFMKKLIKEHYRT-FEK-GHIRDITDSLIEHCQDRRLDE--NANVQLSDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRD-RQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHDQELWGDPNEFRPERFLTSSG--------------------TLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQQMEFNVSPGEKVDMTPAYGLTLKHARCEHFQVQMRSSGPQHLQA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00184-1", "uniprot_id": "CP1A1_MOUSE", "id": "P00184-1", "name": "Cytochrome P450 1A1", "aln": "-MPSMYG-------LPAFVSATELLLAVTVFCLGFWVVRATRTWVP---KGLKTPPGPWGLPFIGHMLTVGKNPHLS---LTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSCYLEEHVSKEANYLVSKLQKVMAEVGHFDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYLPNSS---LDAFKDLNDKFYSFMKKLIKEHYRT-FEK-GHIRDITDSLIEHCQDRKLDE--NANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRD-RQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLTPSG--------------------TLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVSPGEKVDMTPTYGLTLKHARCEHFQVQMRSSGPQHLQA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04798-1", "uniprot_id": "CP1A1_HUMAN", "id": "P04798-1", "name": "Cytochrome P450 1A1", "aln": "-----ML-------FPISMSATEFLLASVIFCLVFWVIRASRPQVP---KGLKNPPGPWGWPLIGHMLTLGKNPHLA---LSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPS---LNAFKDLNEKFYSFMQKMVKEHYKT-FEK-GHIRDITDSLIEHCQEKQLDE--NANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRS-RRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG--------------------AIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05177-1", "uniprot_id": "CP1A2_HUMAN", "id": "P05177-1", "name": "Cytochrome P450 1A2", "aln": "---MALS-------QSVPFSATELLLASAIFCLVFWVLKGLRPRVP---KGLKSPPEPWGWPLLGHVLTLGKNPHLA---LSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPA---LQRFKAFNQRFLWFLQKTVQEHYQD-FDK-NSVRDITGALFKHS--KKGPR--ASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRE-RRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT-------------------AINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64678-1", "uniprot_id": "CP1B1_RAT", "id": "Q64678-1", "name": "Cytochrome P450 1B1", "aln": "-MATSLSADSPQQLSSLSTQQTILLLLVSVLAIVHLGQWLLRQWRR---KPWSSPPGPFPWPLIGNAASVGRASHLY---FARLARRYGDVFQIRLGSCPVVVLNGESAIHQALVQQGGVFADRPPFASFRVVSGGRSLAFGHYS-ERWKERRRAAYGTMRAFSTR---HPRSRGLLEGHALGEARELVAVLVRRCAGGACLDPTQPIIVAVANVMSAVCFGCRYNHDDAEFLELLSHNEEFGRTVGAGSLVDVMPWLQLFPNPVRTIFREFEQINRNFSNFVLDKFLRHRES-LVPGAAPRDMMDAFILSAEKKATGDPGDSPSGLDLEDVPATITDIFGASQDTLSTALLWLLILFTRYPDVQARVQAELDQVVGRD-RLPCMSDQPNLPYVMAFLYESMRFTSFLPVTLPHATTANTFVLGYYIPKNTVVFVNQWSVNHDPAKWSNPEDFDPARFLDKDG--------------------FINKALASSVMIFSVGKRRCIGEELSKTLLFLFISILAHQCNFKANQNEPSNMSFSYGLSIK-PKSFKIHVSLRESMKLLDSAVEKLQAEEACQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64429-1", "uniprot_id": "CP1B1_MOUSE", "id": "Q64429-1", "name": "Cytochrome P450 1B1", "aln": "-MATSLSADSPQQLSSLSTQQTTLLLLFSVLAAVHLGQWLLRQWQR---KPWSSPPGPFPWPLIGNAAAVGQASHLY---FARLARRYGDVFQIRLGSCPVVVLNGESAIHQALVQQGSIFADRPPFASFRVVSGGRSLAFGHYS-EHWKTQRRSAYSTMRAFSTR---HPRSRGLLEGHALAEARELVAVLVRRCAGGAFLDPTQPVIVAVANVMSAVCFGCRYNHDDAEFLELLSHNEEFGRTVGAGSLVDVLPWLQLFPNPVRTTFRKFEQLNRNFSNFVLDKFLRHRES-LVPGAAPRDMTDAFILSAEKKASGAPGDDSSGLDLEDVPATITDIFGASQDTLSTALLWLLILFTRYPDVQARVQAELDQVVGRD-RLPCMSDQPNLPYVMAFLYESMRFSSFLPVTIPHATTANTFVLGYYIPKNTVVFVNQWSVNHDPAKWPNPEDFDPARFLDKDG--------------------FINKALASSVMIFSVGKRRCIGEELSKMLLFLFISILAHQCNFKANQNESSNMSFSYGLTIK-PKSFRIHVSLRESMELLDNAVKKLQTEEGCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16678-1", "uniprot_id": "CP1B1_HUMAN", "id": "Q16678-1", "name": "Cytochrome P450 1B1", "aln": "-MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRR---QLRSAPPGPFAWPLIGNAAAVGQAAHLS---FARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHYS-EHWKVQRRAAHSMMRNFFTR---QPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCES-LRPGAAPRDMMDAFILSAEKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRD-RLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDG--------------------LINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISILAHQCDFRANPNEPAKMNFSYGLTIK-PKSFKVNVTLRESMELLDSAVQNLQAKETCQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05093-1", "uniprot_id": "CP17A_HUMAN", "id": "P05093-1", "name": "Steroid 17-alpha-hydroxylase/17,20 lyase", "aln": "------------------------MWELVALLLLTLAYLFWPKRRC---PGAKYPKSLLSLPLVGSLPFLPRHGHMHNN-FFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDG-------DQKLEKIICQEISTLCDMLATHNGQS--IDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRS-DSITNMLDTLMQAKMNSDNGNAGPD--QDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAG--------------------TQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQAEGST--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRM7-1", "uniprot_id": "CP307_DROME", "id": "Q9VRM7-1", "name": "Cytochrome P450 307a1", "aln": "MLAALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPRE---FSCFYMKMSQIGCEEMEHWNRELGNQLVPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEINQGHPLDFLPWLYPFYQRH---LNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLEDKDVS---------RNTIIFMLEDFIGG-HSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSSSP--IVPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPES--LALPADCFPLVLTPREKIGPL--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *::* : : . : : ::** : .: :* :::. ::.* ::* : .** : ... . ::* :. * : :: . : :*:: . : . :: : . . : . . *..* * : : : : : . .: . : : : : : : *::*. .: . : * : : :: *:* : . * : * : * : * :* . :** : :: : : : * *::* : :: . * :*.:* * *** *. * * ***: : : **.: : :: :: . . * ", "identical_positions": 46, "similar_positions": 120, "identity": "7.97%" }, { "cls_id": "homologset.agr.FB:FBgn0003499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51774-1", "uniprot_id": "EGR2_RAT", "id": "P51774-1", "name": "E3 SUMO-protein ligase EGR2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTAKAVDKIPVTLSG-------FMHQLPDSLYPVEDLAAP---SVTIFPNGELGGP--------------------------------------FDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPI-------------------------------------------------------------------------------SAPRNQTFTYMGKFS---------------IDPQYP-GASCYPEGIINIVSAGILQGVTPPASTTA------------SSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPPTTSTSSLAYQ-PPPSYPSP------------------------KPAMDPGLIPMIPDYPGFFPSPCQRDPHG------------AAGPDRKPFPCPLDSLRV-PPPLTPLSTIRNFTLGGPSAGVTGPGASGGGEGPRLPGSGSAAVTA--------TPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAP-SSSASAQSSASGPGGSQAGGSLCG----------NSAIGGPLASCTSRTRTP-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08152-1", "uniprot_id": "EGR2_MOUSE", "id": "P08152-1", "name": "E3 SUMO-protein ligase EGR2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTAKAVDKIPVTLSG-------FMHQLPDSLYPVEDLAAS---SVTIFPNGELGGP--------------------------------------FDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPI-------------------------------------------------------------------------------SAPRNQTFTYMGKFS---------------IDPQYP-GASCYPEGIINIVSAGILQGVTPPASTTA------------SSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPSTTSTSSLAYQ-PPPSYPSP------------------------KPAMDPGLIPMIPDYPGFFPSPCQRDPHG------------AAGPDRKPFPCPLDSLRV-PPPLTPLSTIRNFTLGGPGAGVTGPGASGGGEGPRLPGSGSAAVTA--------TPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAP-SAPPSAQSSASGPGGSQAGGSLCG----------NSAIGGPLASCTSRTRTP-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05159-1", "uniprot_id": "EGR2B_DANRE", "id": "Q05159-1", "name": "Early growth response protein 2b", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAKTLEKAPVSLGG-------FVHPLADSIYSVDELGTTLPASVTIYN--DLGGH--------------------------------------YEQIN--AGDGLINGDMSTEKRALDLAYSSTFAQP-------------------------------------------------------------------------------AGPRNQTFTYMGKFS---------------IDSQYP-GN-WNPEGVINIVSAGILGMTQP--SSAS------------SSPASSVSPSHFSSTLS--CTMAQNQADMEHIYSPPP---PYSGC-GEVYQDPSAFLS----TSTCPISY--PPPSYSSP------------------------KPNADSGLFPIIPDYAGFFQPPCQRDMQ--------------SMPDRKPFSCPLDSFKL-PPPLTPLNTIRNFTLGGP-----GP------DGPRLP-----------------TAYTPQNLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERKSSS---SSTGVSSSERG-----VATSICS----------SSSNQ--------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06889-1", "uniprot_id": "EGR3_HUMAN", "id": "Q06889-1", "name": "Early growth response protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS-------LLNQLPDNLYP-EEIPSA----LNLFS--GSSDS--------------------------------------VVHYNQMATENVMDIGLTNEKPNPELSYSGSFQP---------------------------------------------------------------------------------APGNKTVTYLGKFA---------------FDSP----SNWCQDNIISLMSAGILG--VPPASGAL------------STQTSTAS------------MVQPPQGDVEAMYPALP---PYSNC-GDLYSEPVSFHDP---QGNPGLAY--SPQDYQSA------------------------KPALDSNLFPMIPDYN-LYHHPNDMG----------------SIPEHKPFQG-MDPIRVNPPPITPLETIKAFK-----------------DKQIHPGFG---------------SLPQPPLTLKPIR-PRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKG-GAPSASSAPPVS------LAPVVT----------TCA----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43301-1", "uniprot_id": "EGR3_RAT", "id": "P43301-1", "name": "Early growth response protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS-------LLNQLPDNLYP-EEIPSA----LNLFS--GSSDS--------------------------------------VAHYTQMATENVMDIGLTNEKPNPELSYSGSFQP---------------------------------------------------------------------------------APGNKTVTYLGKFA---------------FDSP----SNWCQDNIISLMSAGILG--VPPASGAL------------STQTTTAS------------MVQPPQGDVEAMYPALP---PYSNC-GDLYSEPVSFHDP---QGNPGLAY--SPQDYQSA------------------------KPALDSNLFPMIPDYN-LYHHPNDMG----------------SIPEHKPFQG-MDPIRVNPPPITPLETIKAFK-----------------DKQIHPGFG---------------SLPQPPLTLKPIR-PRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKG-GAPSASSAPTVS------LAPVVT----------TCA----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43300-1", "uniprot_id": "EGR3_MOUSE", "id": "P43300-1", "name": "Early growth response protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS-------LLNQLPDNLYP-EEIPSA----LNLFS--GSSDS--------------------------------------VAHYNQMATENVMDIGLTNEKPNPELSYSSSFQP---------------------------------------------------------------------------------APGNKTVTYLGKFA---------------FDSP----SNWCQDNIISLMSAGILG--VPPASGAL------------STQTSTAS------------MVQPPQGDVEAMYPALP---PYSNC-GDLYSEPVSFHDP---QGNPGLAY--SPQDYQSA------------------------KPALDSNLFPMIPDYN-LYHHPNDMG----------------SIPEHKPFQG-MDPIRVNPPPITPLETIKAFK-----------------DKQIHPGFG---------------SLPQPPLTLKPIR-PRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKG-GAPSASSAPTVS------LAPVVT----------TCA----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08154-1", "uniprot_id": "EGR1_RAT", "id": "P08154-1", "name": "Early growth response protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNYPKLEEMMLLSNGAPQFLGAAGTPEGSGGNNSSSSSSSSSGGGGGGGSNSGSS--AFNPQGEPSEQPYEHLTTESFSDIALNNEKALVETSYPS------------------------------------------------------------------------------------QTTRLPPITYTGRFS---------------LEPAPNSGNTLWPEPLFSLVSG-LVSMTNPPTS--------------SSSAPSPAASSSSSASQSPPLSCAVPSNDSSPIYSAAP---TFPTPNTDIFPEPQSQAFPG--SAGTALQY--PPPAYPAT------------------------KGG---FQVPMIPDYL-FPQQQGDLS---------------LGTPDQKPFQG--LENRTQQPSLTPLSTIKAFATQS--------------GSQDLKALN----------------NTYQSQLIKPSR-MRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK--SVVASSAASSLSSYPSPVATSYPS--------PATTSFPSPVPTSYSSPGSSTYPSPA----HSGFPSPSVATTYASVPPAFPAQVS-TFQSAGVSNSFS--TSTGLSDMTATFSPRTIEIC---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08046-1", "uniprot_id": "EGR1_MOUSE", "id": "P08046-1", "name": "Early growth response protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGTPEGSGGN---SSSSTSSGGGGGGGSNSGSS--AFNPQGEPSEQPYEHLTTESFSDIALNNEKAMVETSYPS------------------------------------------------------------------------------------QTTRLPPITYTGRFS---------------LEPAPNSGNTLWPEPLFSLVSG-LVSMTNPPTS--------------SSSAPSPAASSSSSASQSPPLSCAVPSNDSSPIYSAAP---TFPTPNTDIFPEPQSQAFPG--SAGTALQY--PPPAYPAT------------------------KGG---FQVPMIPDYL-FPQQQGDLS---------------LGTPDQKPFQG--LENRTQQPSLTPLSTIKAFATQS--------------GSQDLKALN----------------TTYQSQLIKPSR-MRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK--SVVASPAASSLSSYPSPVATSYPS--------PATTSFPSPVPTSYSSPGSSTYPSPA----HSGFPSPSVATTFASVPPAFPTQVS-SFPSAGVSSSFS--TSTGLSDMTATFSPRTIEIC---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18146-1", "uniprot_id": "EGR1_HUMAN", "id": "P18146-1", "name": "Early growth response protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGAPEGSGSN--SSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHLTAESFPDISLNNEKVLVETSYPS------------------------------------------------------------------------------------QTTRLPPITYTGRFS---------------LEPAPNSGNTLWPEPLFSLVSG-LVSMTNPPAS--------------SSSAPSPAASS-ASASQSPPLSCAVPSNDSSPIYSAAP---TFPTPNTDIFPEPQSQAFPG--SAGTALQY--PPPAYPAA------------------------KGG---FQVPMIPDYL-FPQQQGDLG---------------LGTPDQKPFQG--LESRTQQPSLTPLSTIKAFATQS--------------GSQDLKALN----------------TSYQSQLIKPSR-MRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK--SVVASSATSSLSSYPSPVATSYPSPVTTSYPSPATTSYPSPVPTSFSSPGSSTYPSPV----HSGFPSPSVATTYSSVPPAFPAQVS-SFPSSAVTNSFS--ASTGLSDMTATFSPRTIEIC---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26632-1", "uniprot_id": "EGR1_DANRE", "id": "P26632-1", "name": "Early growth response protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAKTEMLLP-ALQISDPL-SFPHSP-TDNYPKLEEMIMLNSAGTPFLNAT-APEG-----------------------------AVFGSGEPGEQ-FDHLAGDTLSEISM--EKPLSDQTYS--------------------------------------------------------------------------------------TQRLPPISYTGRFT---------------LEPATNCSNSLWAEPLFSLVSG-LVGINPPPASIPSSTS---QATHPSSSSTSSIPSSSSSSTSSASLSCSVHQSEPNPIYSAAP---TYSSASPDIFPES-GPNFST--TVGTSLQY--SSSTYPSA------------------------KTCNPSFSVPMIPDYL-FTQQQSEIS---------------LVPPDQKPIQT--QAG--QQPALTPLHTIKAFATQT--------------GSQDLKSV-------------------YQSQLIKPSR-MRKYPNRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEKGATAAVQSSVSNISISASSPVSSYPS---------PITSYPSPVS-SFPSPVNSCYSSPV----HTSYPSPSIATTYPSATSTFQTQVATSFPTSVASNIYSSPVTTPLPDMQSALSPRTADIC---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGW2-1", "uniprot_id": "A0A0B4KGW2_DROME", "id": "A0A0B4KGW2-1", "name": "", "aln": "MLLTMRRQNELIVGSQQHPSATSSASSSAGATSSPGLSGQNLNLVAGAGAATNSTSANSQDSLNTPTTPLLGLSRNPLQFAPPPAPPIAVPNPAASGPTFGYYQTVNAAPPIHHSPAATSEVSTAPQPPVELDEYVDILQVQQLLLDSSAAAAAAANNPPTTEQSVQQPQQNTVVQPHPHQQQQQQQQQQQPQQQQQQPQQILAKPRPRINLQKATEYAAQLAQAESSSPGSRRVLLDYPSPYLYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAAQSSGSPSTATYLSPAQFGGSHHGGASTSSNSLNSSSTASSSSTSSSLLHYTTASAAAAAAAAAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSGQHSPTSSAVEQVEAHKQLIEALPGDLNTPVTTSSDIPSFFGPTTVVEPPPITGSIESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTTTTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQQYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQASKISYRGIFTTTGNAMNAAAAAAAAAAQQQHQQQQQHQQQLPSPQLGVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPSYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLKLVPVK-PRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEKVRGEQQQQQQQQQQQQQQQQQQQLQQQQEQHHLSLQQHQQYQQHHLLHSADLAIVTSSASMXRLENSASSVDQAQTPTPTPAPAATQKVSLALALDLDESAFPFELTSDYGTLSPLTSPRQFNYVWVGQDSSQPFFYKDNVSVQEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : . :: : : .:* * *: : : . . : * . . : . .. . .: . : .. * .. : . .** : .. :. * : * . : : * *********** ****:.**.* **************:*****:**********.********************:*: **********:***:*:*::*: :* . ", "identical_positions": 95, "similar_positions": 60, "identity": "7.47%" }, { "cls_id": "homologset.agr.FB:FBgn0003502", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA94-1", "uniprot_id": "A0A0G2KA94_RAT", "id": "A0A0G2KA94-1", "name": "Tyrosine-protein kinase", "aln": "MGLVSACQTPGSAVWPALSPVLCQHALGQESRDLQWQEKEQQKTEMNFN-------TILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLTYYEGR-AE--KKYRKGFIDISKIKCVEIVKND--DGIIPCQNKFPFQ---------------------------------VVHDANTLYIFAPSPQSRDRWVKKLKEEI-KNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGC-------------EKYNLFESSIRKTLPPAP-----EIK-RRPPPPIP---------------------------PEEE-NTEEIVVAM--------------------------------------------YDFQATE--AHDLRLERGQEYIILEKNDTHWWRARDKYGSEGY-----IPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSS---GFRHYHIKETATSPKK-YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDV--LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLPRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVECEETFGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24604-1", "uniprot_id": "TEC_MOUSE", "id": "P24604-1", "name": "Tyrosine-protein kinase Tec", "aln": "---------------------------------------------MNFN-------TILEEILIKRSQQKKKTSLLNYKERLCVLPKSVLSYYEGR-AE--KKYRKGVIDISKIKCVEIVKND--DGVIPCQNKFPFQ---------------------------------VVHDANTLYIFAPSPQSRDRWVKKLKEEI-KNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGC-------------EKYNLFESSIRKTLPPAP-----EIKKRRPPPPIP---------------------------PEEE-NTEEIVVAM--------------------------------------------YDFQATE--AHDLRLERGQEYIILEKNDLHWWRARDKYGSEGY-----IPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSS---GFRHYHIKETATSPKK-YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDM--LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDELVECEETFGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42680-1", "uniprot_id": "TEC_HUMAN", "id": "P42680-1", "name": "Tyrosine-protein kinase Tec", "aln": "---------------------------------------------MNFN-------TILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGR-AE--KKYRKGFIDVSKIKCVEIVKND--DGVIPCQNKYPFQ---------------------------------VVHDANTLYIFAPSPQSRDLWVKKLKEEI-KNNNNIMIKYHPKFWTDGSYQCCRQTEKLAPGC-------------EKYNLFESSIRKALPPAP-----ETKKRRPPPPIP---------------------------LEEEDNSEEIVVAM--------------------------------------------YDFQAAE--GHDLRLERGQEYLILEKNDVHWWRARDKYGNEGY-----IPSNYVTGKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSS---GFRHYHIKETTTSPKK-YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDV--LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEETFGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NFV1-1", "uniprot_id": "A0A8M1NFV1_DANRE", "id": "A0A8M1NFV1-1", "name": "Tyrosine-protein kinase", "aln": "---------------------------------------------MSLP-------HILEETLIKRSQQKKRTSPLNYKERVFVLTKSKLTYYELR-AE--KRFKKGSVDLQRVKCVEIVKNN--TTVIPCQNKYPFQ---------------------------------VVYDSSTLYIFAPSNESRSVWVQNIKEEI-RNNPLIADKYHSQFWQEGEWLCCGQVDKLAPGC-------------EGYNLFGDVSRKPLPPVPEDQNISCTGRRPPPPPPG-----------------------ETKQEEEEPEEEVVIAL--------------------------------------------YDFEGLE--PHDLTLKTGEEYVILEKCEVNWYKARNKEGKQGY-----IPSNYVTEKASDKLEQFIWFSKNVNRNKAEELLRKEGKEGGFMVRLSSNTGTYTVSLYTKSTSDGAA---AIRHYQIKEIHASPKQ-FYLAEKYIFTSIPELIEYHKHNAAGLVSRLRHAVGDQKREAPTTAGFSYDKWEINPSELTFMKELGSGQFGVVRLGKWRAQHKVAIKTIREGAMSEDDFIEEAKIMMNLSHRNLVQLYGVCTQQKPIYLVTEFMELGCLLNFLRQRRGTLAAQD--LLGICHDISQGMQHLEENRFIHRDLAARNCLVNSSMVVKVSDFGMTRYVLDDQYWSSSGTKFPVKWSPPEVFNFCRYSSKSDVWSFGVLMWEVFTEGKMPFEHSQNHEVVLMVTQGHRLYRPKKAAPHIYNIMKMCWMEKPDERPTFSETSLMITNELEDDGSVS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A7W7-1", "uniprot_id": "D4A7W7_RAT", "id": "D4A7W7-1", "name": "Tyrosine-protein kinase", "aln": "---------------------------------------------MNNF-------ILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGK--KRTLKGSIELSRIKCVEIVKS---DISIPCHYKYPFQTL---------------------------TSFQVMHDNYLLYVFAPDCESRQRWVLTLKEET-RNNNSLVSKYHPNFWMDGRWRCCSQLEKLAVGC-------------APYDPTKNASKKPLPPTP----------EDNR------------------------------RSFQEPEETLVIAL--------------------------------------------YDYQTND--PQELALRRDEEYYLLDSSEIHWWRVQDKNGHEGY-----APSSYLVEKSPNSLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENN--PCIKHYHIKETNDSPKR-YYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAET--LLGMCLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASPHVYQVMNHCWKEKPEDRPPFSRLLSQLAEIAECGL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03526-1", "uniprot_id": "ITK_MOUSE", "id": "Q03526-1", "name": "Tyrosine-protein kinase ITK/TSK", "aln": "---------------------------------------------MNNF-------ILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGK--KRTLKGSIELSRIKCVEIVKS---DISIPCHYKYPFQTL---------------------------VYLQVVHDNYLLYVFAPDCESRQRWVLTLKEET-RNNNSLVSKYHPNFWMDGRWRCCSQLEKPAVGC-------------APYDPSKNASKKPLPPTP----------EDNR------------------------------RSFQEPEETLVIAL--------------------------------------------YDYQTND--PQELALRCDEEYYLLDSSEIHWWRVQDKNGHEGY-----APSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISEN---PCIKHYHIKETNDSPKR-YYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAET--LLGMCLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAEAGL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08881-1", "uniprot_id": "ITK_HUMAN", "id": "Q08881-1", "name": "Tyrosine-protein kinase ITK/TSK", "aln": "---------------------------------------------MNNF-------ILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGK--KRTLKGSIELSRIKCVEIVKS---DISIPCHYKYPFQ---------------------------------VVHDNYLLYVFAPDRESRQRWVLALKEET-RNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGC-------------AQYDPTKNASKKPLPPTP----------EDNR------------------------------RPLWEPEETVVIAL--------------------------------------------YDYQTND--PQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGY-----VPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENN--PCIKHYHIKETNDNPKR-YYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAET--LLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H751-1", "uniprot_id": "A0AC58H751_DANRE", "id": "A0AC58H751-1", "name": "Tyrosine-protein kinase", "aln": "--------------------------------------MLQILESMKNHSLISERGVILKETLYKKSQQKRRTSPCNYKERTFILNTQDLAYFEQRPGK--KPTQKGCIELSHIKCVEIVRS---DVPIPCDYKYPFQ---------------------------------IIHDSYYLYVFAPDNDCRLKWVKALKEAI-QNN-SLFLKYHPDFWGEGKWRCCQQTEKLATGC-------------SEYYPN---GAKPLPPTP----------DPSR------------------------------RSS-EPEERIVVAL--------------------------------------------RNFTPKE--HTDLPLQKDEEYFIVDCSEPNWWTVKDKDGNVGS-----VPCIYVTEKLSNNIEKFEWYNKDINRTEAEDLLMQENKDGGFMVRNSKHAGVYTVSIFTRVSGSNGEKCPQVKHYQIKVQSEGEKVLYYLAEKYLFPTIPELIRYHQHNPAGLITRLRHCVSRNVPNSARIKELSSDKWEIHPDEVKLSVELGSGQFGLVWKGSWQDME-VAVKTVREGFMSEEEFKEEAQVMMKLSHNRLVQLYGVVTQRSPIYLVFEFMENGCLTEFLRAKKGKLSQKA--LLEMCLDVSEGMAYLESSNFIHRDLAARNCLVSENSVVKIADFGMTRFVLDDQYTSSHGSKFPVRWSSPEVIKFGKYSSKSDVWSFGVFMWEVYSEGRTPYDNRSNSEVVETLNAGHRLLKPRLCPQSVYELMQWSWKEKPEDRPSFALLLHELACLDQEP-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LVI0-1", "uniprot_id": "F1LVI0_RAT", "id": "F1LVI0-1", "name": "Tyrosine-protein kinase", "aln": "-----------------------------------------MDNNMDSK-------SILEELLLKKSQQKKKMSPINYKERLFVLTKTSLSYYEYDKMK--RGSRKGSIEVKKIRCVEKVNL---EEQTPVERQYP---------------------------------FQIVYKDGLLYVYASNEESRCQWLKALQKEI-RGNPHLLIKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY-AD----LHIAISDEKHRAPTFPERILKIPRAVPILKMDASSS-----------------------SAIPPQYDSHLKKSYDSQPTV---------------------------------------NIRYIPREDCPDWWQIRKPKSE---EDIARSNQLERNIVSHSPSKMSWGFPESSSSEE-EENLDAYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMGMYTVSLFSKAVNDKKG---TVKHYHVHTNAE--NK-LYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPVSVALGSGIWELKREEIALLKELGSGQFGVVQLGKWKGQYSVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKNHGKGLESSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQDKP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97504-1", "uniprot_id": "BMX_MOUSE", "id": "P97504-1", "name": "Cytoplasmic tyrosine-protein kinase BMX", "aln": "---------------------------------------------MESK-------SILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMK--RGSRKGSIEIKKIRCVEKVNL---EEQTPVERQYP---------------------------------FQIVYKDGLLYVYASNEESRCQWLKALQKEI-RGNPHLLIKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY-AD----LHIAISDEKHRAPTFPERLLKIPRAVPVLKMDASSS-----------------------GAILPQYDSYSKKSCGSQPTS---------------------------------------NIRYIPREDCPDWWQVRKLKSE---EDIACSNQLERNIASHSTSKMSWGFPESSSSEE-EENLHAYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMGMYTVSLFSKAVNDKKG---TVKHYHVHTNAE--NK-LYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPVSVALGSGIWELKREEITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQDKP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51813-1", "uniprot_id": "BMX_HUMAN", "id": "P51813-1", "name": "Cytoplasmic tyrosine-protein kinase BMX", "aln": "---------------------------------------------MDTK-------SILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMK--RGSRKGSIEIKKIRCVEKVNL---EEQTPVERQYP---------------------------------FQIVYKDGLLYVYASNEESRSQWLKALQKEI-RGNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY-AN----LHTAVNEEKHRVPTFPDRVLKIPRAVPVLKMDAPSS-----------------------STTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKK-----------------IYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVN-HTTSKISWEFPESSSSEE-EENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKG---TVKHYHVHTNAE--NK-LYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKDKH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K6M9-1", "uniprot_id": "A0A0G2K6M9_RAT", "id": "A0A0G2K6M9-1", "name": "Tyrosine-protein kinase", "aln": "----------------------------------------------MAA-------VILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVP---EKNPPPERQIPVPRRGEESSEME----------QISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVI-RYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGS----LKPGSSHRKTKKPLPPT-----PEEDQILKKPLPPE-----------------------PTAAPISTSELKKVVAL--------------------------------------------YDYMPMN--ANDLQLRKGEEYFILEESNLPWWRARDKNGQEGY-----IPSNYVTEA-EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGEPQG---VIRHYVVCSTPQ--SQ-YYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKIPYERFTNSETAEHIAQGLRLYRPHLASDRVYTIMYSCWHEKADERPSFKILLSNILDVMDEES----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35991-1", "uniprot_id": "BTK_MOUSE", "id": "P35991-1", "name": "Tyrosine-protein kinase BTK", "aln": "----------------------------------------------MAA-------VILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVIP---EKNPPPERQIP--RRGEESSEME----------QISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVI-RYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGS----LKPGSSHRKTKKPLPPT-----PEEDQILKKPLPPE-----------------------PTAAPISTTELKKVVAL--------------------------------------------YDYMPMN--ANDLQLRKGEEYFILEESNLPWWRARDKNGQEGY-----IPSNYITEA-EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGEPQG---VIRHYVVCSTPQ--SQ-YYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEES----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06187-1", "uniprot_id": "BTK_HUMAN", "id": "Q06187-1", "name": "Tyrosine-protein kinase BTK", "aln": "----------------------------------------------MAA-------VILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVP---EKNPPPERQIP--RRGEESSEME----------QISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVI-RYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGS----LKPGSSHRKTKKPLPPT-----PEEDQILKKPLPPE-----------------------PAAAPVSTSELKKVVAL--------------------------------------------YDYMPMN--ANDLQLRKGDEYFILEESNLPWWRARDKNGQEGY-----IPSNYVTEA-EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGDPQG---VIRHYVVCSTPQ--SQ-YYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42681-1", "uniprot_id": "TXK_HUMAN", "id": "P42681-1", "name": "Tyrosine-protein kinase TXK", "aln": "--------------------------------------------------------MILSSYNTIQSVFCCCCC-CSVQKRQ-MRTQISLSTDEELPEK-------------------------------------------------------------------------------------YTQRRRPWLSQLSNKK-QSNTGRVQPSK---------------------------------------------RKPLPPLPP--------------------------------------------SEVAEEKIQVKAL--------------------------------------------YDFLPRE--PCNLALRRAEEYLILEKYNPHWWKARDRLGNEGL-----IPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEA---AIKHYQIKKNDS--GQ-WYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEM--LLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42682-1", "uniprot_id": "TXK_MOUSE", "id": "P42682-1", "name": "Tyrosine-protein kinase TXK", "aln": "--------------------------------------------------------MILSSYSSFQSVLCCCCCRCSVQKRQ-VRTQISLSREEELSEK-------------------------------------------------------------------------------------HSQRQRPWFAKLMGKT-QSNRGGVQPSK---------------------------------------------RKPLPPLP---------------------------------------------QEPPDERIQVKAL--------------------------------------------YDFLPRE--PGNLALKRAEEYLILERCDPHWWKARDRFGNEGL-----IPSNYVTENRLANLEIYEWYHKNITRNQTERLLRQEAKEGAFIVRDSRHLGSYTISVFTRARRHTQS---SIKHYQIKKNDS--GQ-WYITERHLFPSVPELIQYHQYNAAGLISRLRYPIGLLGSCLPATSGFSYEKWEIDPSELAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKAL--LLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIAETW-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08630-1", "uniprot_id": "BTKL_DROME", "id": "P08630-1", "name": "Tyrosine-protein kinase Btk", "aln": "-----------MMGTKHRNSHVNGSIKSSSSLRSSSKSFQAKMDLMSER----LYDVVKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVE--RRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFVKLVVALYPFKAIE--GGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGY-----IPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVP---QS---HVKHYHIKQNAR---CEYYLSEKHCCETIPDLINYHRHNSGGLACRLKS--SPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTLTD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: . : * :: : . . : *. : * : . * : : :. . : :: * :. : *: .* .:* ** *:* *:** * * **:*:. .:** : *::*.: ::* :* **::* .*: **: . : * :. :: : *:*.* **:* * * .*:* :.** *.*::* :**: * :* * .**::*** :. *: :: *:: *.* ::*: : ** :* ::.:.* .** :***********. :*::***::*:****:* ** *:***::*..***: : ::*****:*::*::***::: *: *: * :.. : * * :*: .. :* :* .* . .. **.: : : ", "identical_positions": 121, "similar_positions": 139, "identity": "14.68%" }, { "cls_id": "homologset.agr.FB:FBgn0003507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17679-1", "uniprot_id": "GATA1_MOUSE", "id": "P17679-1", "name": "Erythroid transcription factor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFPGLGALGTSEPLPQFVDSALVSSPSDS-----------------------TGFFSSGPEGLDAASSSTSPN----------------------------------------------------------AATAAASALAY--------------YREAEAYRHSPVFQVYPLLNSMEGIPGGSPYAS------------------WAYGKTALYP---------------ASTVCPSHEDAPSQALEDQEGKSNNTFLDTLKTERLSPD------LLTLGTALPAS------------------------------------------------------------------------------------------------------------LPVTGSAYGG-----ADFPSPFFSPTG-------------------SPLSSAAYSSPKFHGSLPLAPCEARECVNCG-----------ATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPK---------------------------------------------------------KRMIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYFKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSNLAGAGAAEGPAG---------------------------------------------------GFMVVAGSSSSGNCGEVASGLALGTAGTAHLYQG-----------------------LGPVVLSGP-------VSHLMPFPGPLLGSPT------------------------------------------------------------------------------------------------TSFPTGPAPTTSSTSVIAPLSS---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43429-1", "uniprot_id": "GATA1_RAT", "id": "P43429-1", "name": "Erythroid transcription factor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFPGLGALGTSEPLPQFVDSALVSSTSDS-----------------------AGFFSSGPESLDTASSSTSPN----------------------------------------------------------AATAAATALAY--------------YREAEAYRHSPVFQVYPLLNSMEGIPGSSPYAS------------------WAYSKTALYP---------------ASTVCPSHEDAPSQTLEDPDGKNNNTFLETLKTERLSPD------LLTLGTALPTS------------------------------------------------------------------------------------------------------------LPVTSSAYGG-----ADFPSPFFSPTG-------------------SPLSSAAYSSPKFHGSLPLAPCEARECVNCG-----------ATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPK---------------------------------------------------------KRMIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLAGAGAAEGPAG---------------------------------------------------GFMVVAGGSSSGNCGEVAPGLTLGTAGTAHLYQG-----------------------LGPVVLSGP-------VSHLMSFPGPLLGSPT------------------------------------------------------------------------------------------------ASFPTGPVPTTTSTSVVSPLSS---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15976-1", "uniprot_id": "GATA1_HUMAN", "id": "P15976-1", "name": "Erythroid transcription factor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFPGLGSLGTSEPLPQFVDPALVSSTPES-----------------------GVFFPSGPEGLDAAASSTAPS----------------------------------------------------------TATAAAAALAY--------------YRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAG------------------WAYGKTGLYP---------------ASTVCPTREDSPPQAVEDLDGKGSTSFLETLKTERLSPD------LLTLGPALPSS------------------------------------------------------------------------------------------------------------LPVPNSAYGG-----PDFSSTFFSPTG-------------------SPLNSAAYSSPKLRGTLPLPPCEARECVNCG-----------ATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPK---------------------------------------------------------KRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAG---------------------------------------------------GFMVVAGGSGSGNCGEVASGLTLGPPGTAHLYQG-----------------------LGPVVLSGP-------VSHLMPFPGPLLGSPT------------------------------------------------------------------------------------------------GSFPTGPMPPTTSTTVVAPLSS---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52172-1", "uniprot_id": "SRP_DROME", "id": "P52172-1", "name": "Box A-binding factor", "aln": "MTKTTKPKEKAAAGGAVIGSGSGLGSVTKAGGGSLLSNAADSKIRTAKSNNNKRQAGRAATALAATTTASALAATTTAGATGSNAAANETEIAIETENGEAATPTAAATAAAANLSSLESARSQALTSVVSETARQAVTTANASATSTSTVTAATEIATATASDTAATSEAAIDDDPSAINTNNNNNNSKAQNDASESVKTKVISYHQSEDQQQQQQQQAQIYEQQQQFLSQQLISHHQQEQHQQAQQQQHQQVVQEQHQASWLAYDLTSGSAAAAAAAAAAASHPHLFGQFSYPPSHHTPTQLYEHYPSTDPIMRNNFAFYSVYTGGGGGVGVGMTSHEHLAAAAAAAAAVAQGTTPNIDEVIQDTLKDECFEDGHSTDYHVLTSVSDMHTLKDSSPYALTHEQLHQQQHHHQQQLHHHQQQQQQLYHQQQQQQQQQQHHHHHNNSTSSAGGDSPSSSHALSTLQSFTQLTSATQRDSLSPENDAYFAAAQLGSSLQNSSVYAGSLLTQTANGIQYGMQSPNQTQAHLQQQHHQQQQQQHQQHQQQQLQQQQQQHHHNQHQHHNSSSSSPGPAGLHHSSSSAATAAAVAAATAAVNGHNSSLEDGYGSPRSSHSGGGGGGTLPAFQRIAYPNSGSVERYAPITNYRGQNDTWFDPLSYATSSSGQAQLGVGVGAGVVSNVIRNGRAISAANAAAAAAADGTTGRVDPGTFLSASASLSAMAAESGGDFYKPNSFNVGGGGRSKANTSGAASSYSCPGSNATSAATSAVASGTAATAATTLDEHVSRANSRRLSASKRAGLSCSNCHTTHTSLWRRNPAGEPVCNACGLYYKLHSVPRPLTMKKDTIQKRKRKPKGTKSEKSKSKSKNALNAIMESGSLVTNCHNVGVVLDSSQMDVNDDMKPQLDLKPYNSYSSQPQQQLPQYQQQQQLLMADQHSSAASSPHSMGSTSLSPSAMSHQHQTHPHQQQQQQLCSGLDMSPNSNYQMSPLNMQQHQQQQSCSMQHSPSTPTSIFNTPSPTHQLHNNNNNNNNSSIFNNNNNNNSSSNENNNKLIQKYLQAQQLSSSSNSGSTSDHQLLAQLLPNSITAAAAAAAAAAAAAIKTEALSLTSQANCSTASAGLMVTSTPTTASSTLSSLSHSNIISLQNPYHQAGMTLCKPTRPSPPYYLTPEEDEQPALIKMEEMDQSQQQQQQQQHQQQQHGEIMLSRSASLDEHYELAAFQRHQQQQQQLQQQTAALLGQHEQHVTNYAMHKFGVDRETVVKME", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43574-1", "uniprot_id": "GAT1_YEAST", "id": "P43574-1", "name": "Transcriptional regulatory protein GAT1", "aln": "-------------------------------------------------------------------------------------------------------------------------MHVFFPLLFRPSPVLFIACAYIYIDIYIHCTRCTVVNITMSTNRVPNLDPDLNLNKEIWDLYSSAQKILPD--------------------SNRILNLSWRLHNRTSFHRINRIMQHSNS-----------------------IMDFSASPFASGVNAAGPGNN----------------------------------------------------------DLDDTDTDNQQ------------FFLSDMNLNGSSVFENVFDDDDDDDDVETHSIVHS--------------------DLLNDMDS---------------ASQRASHNASGFPNFLDTSCSSSFDDHFIFTNNLPFLNN-------NSINNNHSHN---------------------------------------------------------------------------------------------------------------SSHNNNS-----PSIANNTNANTN--------------------TNTSASTNTNSPLLRRNPSPSIVKPGSRRN--------------SSVRKKKPALKKIKSSTSVQSSATPPSNTSSNPD-------------------------------------------------------------------IKCSNCTTSTTPLWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDIIKKRQRSSTKINNNITPPPSSSLNPGAAGKK--------------------------------------------------KNYTASVAASKRKNSLNIVAPLKSQDIPIPKIASP-----------------------SIPQYLRSN-------TRHHLSSSVPIEAETF------------------------------------------------------------------------------------------------SSFRPDMNMTMNMNLHNASTSSFNN---EAFWKPLDSAIDHHSGDTNPNSNMNTTPNGNLSLDWLNLNL----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42944-1", "uniprot_id": "GZF3_YEAST", "id": "P42944-1", "name": "Protein GZF3", "aln": "---------------------------------------------------------------------------------------------------------------------------------MASQATTLRGYNIRKRDNVFEPKSSENLNSLNQSEEEGHIGRWPPLGYEAVSAEQKS------------------------AVQLRESQAGASISNNMNFKANDKSFSTSTAG----------------------RMSPDTNSLHHILPKNQVKNN-----------------------------------------------------------GQTMDANCNN---------------NVSNDANVPVCKNCLTSTTPLWRRDEHGAMLCN-----------------ACGLFLKLHG----------------KPRPISLKTDVIKSRNRKSNTNHAHNLDNFRNQTLIAELKG---DCNIESSGRKAN-------------------------------------------------------------------------------------------------------------RVTSEDKKKKSSQLLMGTSSTAKISK------------------KPKTESKERSDSHLSATKLEVLMSGDCSRPN-------------LKPKLPKQDTAIYQEKLLTFPSYTDVKEYSNSAHQS---------------------------------------------------------AFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNPSEVP--------------------------------------------------------NQIRSTMSSPDIISAKRNDPAPLSFHMAS-----------------------INDMLETRDR-----AISNVKTETTPPHFIPFLQ-----------------------------------------------------------------------------------------------SSKAPCISKANSQSISNSVSSSDVSGRKFENHPAKDLGDQLSTKLHKEEEIIKLKTRINELELVTDLYRRHINELDGKCRALEERLQRTVKQEGNKGG----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* :.. : . : . : . . . . : : : : . . . . : : . . . : . . . .: .: .: : . * .: . .: :.. :. . .. . . : . . . . : . . . ** ", "identical_positions": 4, "similar_positions": 63, "identity": "0.32%" }, { "cls_id": "homologset.agr.FB:FBgn0003513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41738-1", "uniprot_id": "AHR_RAT", "id": "P41738-1", "name": "Aryl hydrocarbon receptor", "aln": "-MSSGANITYASRKRRKPVQKTVKPVPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRSRGQDQCRAQ-VRDWQD------LQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDETHGLPQPAVYYTPDQ----LPPENTAFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCNKGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSMTLPFMFATGEAVLYEISSPFSPIMDPLPIRTKSNTSRKDWAPQSTPSKDSFHPNSLMSALIQQDESIYLCPPSSP------------APLDSHFLMDSMSECGSWQGSFAVASNEA--------------------LLKHEEIRHTQDVNLTLSGGPSELFPDNKNNDLYSIMRNLGID------FEDIRSMQNEEFFRTDS--SGEVDFKDIDITDEILTYVQDSLNNSTLLNSACQQQ-PVSQHLSCMLQERLQLEQQQQLQQQHPTQTLEPQRQLCQVEVPQHELGQKTKHMQVNGMFASWNPAPPVSFSCPQQERKHYSL-----FSGLQGTAQEFPYKSEVDSMPYTQNFAP------------CNQSLLPEHSKGTQLDFPGRDFERSLHPNASNLEDFVSCLQVPENQRHG-INSQSAMVSPQAYYAGAMSMYQCQAGPQHTPVDQMQYSPEIPGSQAFLSKFQSPSILNEAYSADLSS-IGH-LQTAAHLP---RLAEAQPLPDITPSGFL-----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30561-1", "uniprot_id": "AHR_MOUSE", "id": "P30561-1", "name": "Aryl hydrocarbon receptor", "aln": "-MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQ-IRDWQD------LQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP----DSAQGVDEAHGPPQAAVYYTPDQ----LPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLFAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSTSLPFMFATGEAVLYEISSPFSPIMDPLPIRTKSNTSRKDWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSP------------APLDSHFLMGSVSKCGSWQDSFAAAGSEA--------------------ALKHEQIGHAQDVNLALSGGPSELFPDNKNNDLYNIMRNLGID------FEDIRSMQNEEFFRTDSTAAGEVDFKDIDITDEILTYVQDSLNNSTLMNSACQQQ-PVTQHLSCMLQERLQLEQQQQLQQP-PPQALEPQQQLCQMVCPQQDLG--PKHTQINGTFASWNPTPPVSFNCPQQELKHYQL-----FSSLQGTAQEFPYKPEVDSVPYTQNFAP------------CNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLD-FVSCLQVPENQSHG-INSQSTMVSPQAYYAGAMSMYQCQPGPQRTPVDQTQYSSEIPGSQAFLSKVQSRGIFNETYSSDLSS-IGHAAQTTGHLH---HLAEARPLPDITPGGFL-----------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35869-1", "uniprot_id": "AHR_HUMAN", "id": "P35869-1", "name": "Aryl hydrocarbon receptor", "aln": "MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLN------LQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQ----IPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPFPAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSS---------TAPFENNFFNESMNECRNWQDNTAPMGNDT--------------------ILKHEQIDQPQDVN-SFAGGHPGLFQDSKNSDLYSIMKNLGID------FEDIRHMQNEKFFRNDF--SGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQQQQSLALNSSCMVQEHLHLEQQQQHHQK--QVVVEPQQQLCQK----------MKHMQVNGMFENWNSNQFVPFNCPQQDPQQYNV-----FTDLHGISQEFPYKSEMDSMPYTQNFIS------------CNQPVLPQHSKCTELDYPMGSFEPSPYPTTSSLEDFVTCLQLPENQKHG-LNPQSAIITPQTCYAGAVSMYQCQPEPQHTHVGQMQYNPVLPGQQAFLNKFQN-GVLNETYPAELNN-INN-TQTTTHLQPLHHPSEARPFPDLTSSGFL-----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9V8-1", "uniprot_id": "A0AB13A9V8_DANRE", "id": "A0AB13A9V8-1", "name": "", "aln": "-MSSSN--IYASRKRRKPVQKSVK-QPLTCVKSNPSKRHRDRMNEVLASLAREIPFPQEIVSTLDKLTILRLSVSYLRAKSHFKITLNSKSSSQ-------QANNTKQAQE------QPEGEFLLQAINGFLLVVTSSGIVFYVSSNIEDYLGFHQSDVIHQSVYELIHTEDRHEFQRQLHWALNPGFTPDSRQLVQASP--DASRTCYSPEQ----LSLENSTCLERNFICRLRCLLDSTSGFLAVNFQGRLKFLYGQNESTGDGKRIPPQLALFALACPLQPPSILEIRTKNLMFKTKYKLDFTPIACDTNWNFVLGYTEAELCNSGSGYQFIHAADMMYCAEGHMRMMRTGKTGLTVFRLLTKQNRWVWVQSNGKLVYKNGQPDCIITSHRVITAEEGEENLRNRAMMLPFNFTTGDAVLCAMNCP-----------TSSDPASSDGNTQPKTTR-TVNPDSLLVSLLKQPKSIYLSPADER-----------------SVLVQSLGNK-DLDGIYSINSQES--------------------VSVSRSCPFKQESVFSSER--------DDSCEILNFMGSLGIS------LEDLKFLQHEDLFINMD---LDSHNDMADLSDDILSHVQQSLKT--------KMDCTVSKNTQGNMKEQELIRNPAQTIIP--NDSCDTITLLSQEQQMTFITDKTEPKIQLT-QIQPYTPQKGITYLQIDPHEHQDTR-----PQSYNGTGITLPKSSHSTIQTISQHLQF------------SNLPPFHEQ-VCEALRSP--QVCGNMAEVIDSDIQQVSPLFPPELQPSGCFYLERPILDPKLCTSSSQQLSSSQ----TTEGEPVEFT--TQDLEDLINDMNGVGERNNYSGLDRGMDIRSSLDQQAYIG----TGSPQRNEPPTYAAYV-----------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q75NT5-1", "uniprot_id": "AHRR_RAT", "id": "Q75NT5-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "MMIPSGECTYAGRKRRKPIQKRRLTMGTE--KSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSP---EDHSSRGFP------VQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADT-DNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAP-VLPSVTEMKMKSAFLKAKHRADIVVT-MDSRAKAVTSLCESELHPK----------------LNYLAGRSNGENVISLFRGQTDRSHWTRALARSSCLCLRGGPD-LLDPKGTSGD---REEDDQKHILRRSPGARGQREMHKYSYGLETPVHLRHLDWSTEQRSQEGTTKLTRQPSKSEP----STCLVPHGSCVPYPGSQG-----------------MFSASNMASFRESLDHPTGTYCSQ--------------------MNRPLPDIHQGQVDPSTCHIPQGSLGSRIPLSGMQCFTARGFS------TEDAKLPS-------------------------------------------------LPVNIGTPCNPVLSLEVPIKMENE-----------------------------SGSQDIVEASTTSCVWLGTGDMTRRHLVG-----FPARMHLKTEPDYRQQVCTPHRGHGILG------------TNP--------------HSRDTVGSCREHAPLYSAHCTCLSP---------------EPPHHLFMCSHSESQHPSLDQDCRAPIVKREPLDSPSWAAPGHVTVPRMFPKNASITVIP------------------------SKGSDGIFLP----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1U7-1", "uniprot_id": "AHRR_MOUSE", "id": "Q3U1U7-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "MMIPSGECTYAGRKRRKPIQKRRLTMGAE--KSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSP---EEHSYRGFP------VQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADT-DNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAP-VLPSVTEMKMKSTFLKAKHRADIVVT-MDSRAKAVTSLCESELHPK----------------LNYLAGKSNGENGISLFRGQTDRSHWARALARSSCLCLRGGPD-LLDPKGTSGD---REEEDQKHILRRSPGAWGQREMHKYSYGLETPVHLRHLNWSTEQRSQESTTKLTRQPSKNEP----STCLVPHGSCVPYPGSQG-----------------MLSASNMASFRDSLDHPTGAYCSQ--------------------MNRPLSDIHQGQVDPSTCHISQGSLGSRIPLTGMQRFTARGFS------TEDAKLPS-------------------------------------------------LPVTIGTPCNPVLSLDVPIKMENE-----------------------------SGSQDIVEASTTSCLWLGTSDMARGHLVG-----FPARMHLKTEPDYRQQACTPHLGHGMLG------------TNP--------------YSRDTVGSCREHAPLYSAHCTCLDP---------------EPPHHFFMCSHSESQHPSLDQDCRAPIVKREPLDSPSWAAPGQVTVPRMFPKSASKTVIP------------------------SKGSDGIFLP----------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9YTQ3-1", "uniprot_id": "AHRR_HUMAN", "id": "A9YTQ3-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "-MIPPGECTYAGRKRRRPLQKQRPAVGAE--KSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSA------VLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAAT-ADAKVKATTSLCESELHGK----------------PNYSAGRSSRESGVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGD---REEE-QHRMLSRASGVTGRR---------ETPGPTKPLPWTAGKHSEDG-ARPRLQPSKNDPP---SLRPMPRGSCLPCPCVQG-----------------TFRNSPIS---HPPSPSPSAYSSR--------------------TSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYP------MEDMKLQG-------------------------------------------------VPMPPGDLCGPTLLLDVSIKMEKD-----------------------------SGCEGAADGCVPSQVWLGASD--RSHPAT-----FPTRMHLKTEPDSRQQVYISHLGHGVRG------------AQP--------------HGRATAGRSRELTPFHPAHCACLEPTDGLPQS--------EPPHQLCARGRGE-QSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVP------------------------PQASGCTFLP----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JIM6-1", "uniprot_id": "E1JIM6_DROME", "id": "E1JIM6-1", "name": "", "aln": "--MSQLGTVYATKRRRRNGKSLKPPPKDGVTKSNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLPHIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLLWNSFLPADMSSMQLAETL-------------------APDKALYLERSFTVRFRCLLDNTSGFLRLDIRGRIKVLHGQNRKTEE-----PPLALFAYCTPFGPPSLLEIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMG-GYDLVHYDDLAYVASAHQELLKTGASGMIAYRYQKKDGEWQWLQTSSRLVYKNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSYLDTGLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQQNQPQTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAFYPVSENLFHQYRLQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAIASKADEKWQETGKYYSGYSSGYGSPTSTPQQIPLKTPKSSPQVMEVISCSSDGPSPVGGATPNGVGSVTPKVELAGTTAAAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRTGAGNPASPQRSTPLGNGLGYASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQMQHDDSGLYSASSHTTSPQQQQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSSCHQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEIILTTHHQQQSQQQQQSLAGYPLHHQLVGVGSGSPPPQPPVALSRSPTTLPAVSSLLNGSASAGGASDIPYQQLAIVSAPLVICAEEVGGGVSSIGRKSSKQQQSLQHLQQQQSLQQQQHAIYQQQHHHSQHHPHHQLLYPANITAHTALAYAPPTAGGAYADGSPLLSFSEVTNTLLNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** ::**: :. *********:*:* * ** :** :::..**:*::*********.**.*. . . :* ::*:::*** :::: .. :*:.: .* .****:*:*::**.:*: :* :** :: *** * . . : : : * * *.*****.:**** ::::*::* *.**:.. . * *:**. * ** *: :. ::::* : * * . . . : ** : . . : * . ..* : . : .. ** :: .: : :: . . . * . . . . * : . : : : . . : *: : : ", "identical_positions": 95, "similar_positions": 121, "identity": "9.12%" }, { "cls_id": "homologset.agr.FB:FBgn0003514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14950-1", "uniprot_id": "ML12B_HUMAN", "id": "O14950-1", "name": "Myosin regulatory light chain 12B", "aln": "------MSSKK--AKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3THE2-1", "uniprot_id": "ML12B_MOUSE", "id": "Q3THE2-1", "name": "Myosin regulatory light chain 12B", "aln": "------MSSKK--AKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8L2UJI1-1", "uniprot_id": "A0A8L2UJI1_RAT", "id": "A0A8L2UJI1-1", "name": "", "aln": "MDLTATMSSKR--AKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLDAMMNEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEAIGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19105-1", "uniprot_id": "ML12A_HUMAN", "id": "P19105-1", "name": "Myosin regulatory light chain 12A", "aln": "------MSSKR--TKTKT-KKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMMNEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64122-1", "uniprot_id": "MYL9_RAT", "id": "Q64122-1", "name": "Myosin regulatory light polypeptide 9", "aln": "------MSSKR--AKAKTTKKRPQSATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEXLEGMMNEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYRER-IDKKGNFNYVEFTRILKHGAKDKDD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ19-1", "uniprot_id": "MYL9_MOUSE", "id": "Q9CQ19-1", "name": "Myosin regulatory light polypeptide 9", "aln": "------MSSKR--AKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMNEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24844-1", "uniprot_id": "MYL9_HUMAN", "id": "P24844-1", "name": "Myosin regulatory light polypeptide 9", "aln": "------MSSKR--AKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPG--------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40423-1", "uniprot_id": "SQH_DROME", "id": "P40423-1", "name": "Myosin regulatory light chain sqh", "aln": "------MSSRKTAGRRATTKKRAQRATSNVFAMFDQAQIAEFKEAFNMIDQNRDGFVEKEDLHDMLASLGKNPTDDYLDGMMNEAPG--------PINFTMFLTLFGERLQGTDPEDVIKNAFGCFDEENMGVLPEDRLRELLTTMGDRFTDEDVDEMYREAPIKN-GLFDYLEFTRILKHGAKDKDEQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06580-1", "uniprot_id": "MLC2_YEAST", "id": "Q06580-1", "name": "Myosin light chain 2", "aln": "----------------------MDHSESLTFNQLTQDYINKLKDAFQMLDEDEDGLISRGDLTKIYATLGKTLTDEEWSKMVPDNDTSTAEVGEEGVSFPIFLSIMGKNLSQFPEREELEESLKAIGRGHDLNVPLNEVIDSLKEAGFENPEEEFAKLFKLFTTNQQATEERTFRGKLFLDSITD----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .* : * * ::*:**:*:*::.**::.: ** .: *::**. ** . *: : :.*.:**:::*:.*. .: :.::: .:.. : : : : *. * . .:*:. :::: .: . : ::: .. .* ", "identical_positions": 28, "similar_positions": 69, "identity": "14.81%" }, { "cls_id": "homologset.agr.FB:FBgn0003517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38983-1", "uniprot_id": "RSSA_RAT", "id": "P38983-1", "name": "Small ribosomal subunit protein uS2", "aln": "MSGGLDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRG-TISREHPWEVMPDLYFYRDPEEIE-KEEQAAAEKAVTKEEFQGEWTAPAPEFTAAQPEVADWSEGVQVPSVPIQQFPT---------------EDWSAQPATEDWSAAPTAQATEWVGATTEWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14206-1", "uniprot_id": "RSSA_MOUSE", "id": "P14206-1", "name": "Small ribosomal subunit protein uS2", "aln": "MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRG-TISREHPWEVMPDLYFYRDPEEIE-KEEQAAAEKAVTKEEFQGEWTAPAPEFTAAQPEVADWSEGVQVPSVPIQQFPT---------------EDWSAQPATEDWSAAPTAQATEWVGATTEWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08865-1", "uniprot_id": "RSSA_HUMAN", "id": "P08865-1", "name": "Small ribosomal subunit protein uS2", "aln": "MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRG-TISREHPWEVMPDLYFYRDPEEIE-KEEQAAAEKAVTKEEFQGEWTAPAPEFTATQPEVADWSEGVQVPSVPIQQFPT---------------EDWSAQPATEDWSAAPTAQATEWVGATTDWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5KQE6-1", "uniprot_id": "RPSA2_HUMAN", "id": "A0A8I5KQE6-1", "name": "Small ribosomal subunit protein uS2B", "aln": "MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEHYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFWEPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRG-TISREHPWEVMPDLYFYRDPEEIE-KEEQAAAEKAVTKEEFQGEWTAPSPEFTATQPEVADWSEGVQVPSVPIQQFPT---------------EDWSAQPATEDWSAAPTAQATEWVGATTDWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803F6-1", "uniprot_id": "RSSA_DANRE", "id": "Q803F6-1", "name": "Small ribosomal subunit protein uS2", "aln": "MSGGLDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYVYKRKSDGVYIINLKKTWEKLLLAARAIVAIENPADVCVISSRNTGQRAVLKFASATGSTTFAGRFTPGTFTNQIQAAFREPRLLIVTDPRADHQPLTEASYVNIPTIALCNTDSPLRYVDIAIPCNNKGPHSVGLMWWMLAREVLRMRG-TISREHPWEVMPDLYFYRDPEEIE-KEEQAAAEKAVGKEEFQGEWTAPVPDFN--QPEVADWSEGVQVPSVPIQQFPAGIEAPGKPAPAEVYAEDWSAQPATEDWSAAPTAQAGDWGGATADWS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38979-1", "uniprot_id": "RSSA_DROME", "id": "P38979-1", "name": "Small ribosomal subunit protein uS2", "aln": "MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAIVAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRG-TISRSVEWPVVVDLFFYRDPEEAE-KEE-AAAKELLPPPKIEEAVDHP-------VEETTNWADEVAAETVGG-------------------VEDWNEDTVKTSWGSDGQF-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32905-1", "uniprot_id": "RSSA1_YEAST", "id": "P32905-1", "name": "Small ribosomal subunit protein uS2A", "aln": "MS-LPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDPEEVEQQVAEEATTEEAGEEEAKEEVTEE-------QAEATEWAEENADN------------------------VEW----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P46654-1", "uniprot_id": "RSSA2_YEAST", "id": "P46654-1", "name": "Small ribosomal subunit protein uS2B", "aln": "MS-LPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTYGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRLDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRNPEEVEQVAEEAAAAEEGEEEEVKEEVTEG-------QAEATEWAEENADN------------------------VEW----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.:. :* :*.* ****. *::.: * *::: :.**: ::*: :***** **** *.** ** *: .**** ********* *.:*.:*******:*** * :* ****::****. * *.: ******:*.**: : *** .::*:******:. **:**:*::*******:** :.* * :: **:***:*** * *: : : : *.::*:: :* ", "identical_positions": 115, "similar_positions": 67, "identity": "36.86%" }, { "cls_id": "homologset.agr.FB:FBgn0003520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68SB1-1", "uniprot_id": "STAU2_RAT", "id": "Q68SB1-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTPMCLVNELARFHSIQPQYKLLNESGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG-------SITPTVELNGLAMKRGEPAIYRPLD-------------------------------------------------PKPFPNYRANYNFRG-MYNQR----YHCPMP------------------KIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVIEKPKLFFKKRPKT-----------IIK--AGPEYG--------------------QGMNPISRLAQIQQARKEKEPDYVLLSERG--MPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS-----TSLQD-------------------QLDKTGENKGWSGPKPGFPEPANNTPKG-------ILHLSPDVYQEMEASRHRVTSGTTLGYLSPKDMNQPSSSFFSVES-PSPTSSAPAARELLMNGTSPAAEAIGLKGSSP--TPPCSSVQPS---------------KQLEYLARIQGF--------------------------------------QAALSALKQFSEQGLESIDGVVNVENGSLEKQAKHLREKADNNQANPGSITQDCKKSKSVI--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJ67-1", "uniprot_id": "STAU2_MOUSE", "id": "Q8CJ67-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTPVCLVNELARFHSIQPQYKLLNESGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG-------SITPTVELNGLAMKRGEPAIYRPLD-------------------------------------------------PKPFPNYRANYNFRG-MYNQR----YHCPMP------------------KIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKT-----------IVK--AGPDYG--------------------QGMNPISRLAQIQQARKEKEPDYILLSERG--MPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS-----TSLQD-------------------PLDKTGENKGWSGPKPGFPEPTNNTPKG-------ILHLSPDVYQEMEASRHRVTSGTTLSYLSPKDMNQPSSSFFSVS--PSSTSSATVARELLMNGTSPTAEAIGLKGSSP--TSPCSSVQPS---------------KQLEYLARIQGF--------------------------------------QAALSALKQFSEQGLESIDGAVNVEKGSLEKQAKHLREKADNNQAKPASISQDCKKSKSAI--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUL3-1", "uniprot_id": "STAU2_HUMAN", "id": "Q9NUL3-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTAMCLVNELARFNRVQPQYKLLNERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPG-------SITPTVELNGLAMKRGEPAIYRPLD-------------------------------------------------PKPFPNYRANYNFRG-MYNQR----YHCPVP------------------KIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDVDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKT-----------IVK--AGPEYG--------------------QGMNPISRLAQIQQAKKEKEPDYVLLSERG--MPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKAS-----TNLQD-------------------QLEKTGENKGWSGPKPGFPEPTNNTPKG-------ILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSIS--PTSNSSATIARELLMNGTSSTAEAIGLKGSSP--TPPCSPVQPS---------------KQLEYLARIQGF--------------------------------------QAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCKKSNSAV--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW47-1", "uniprot_id": "STAU2_DANRE", "id": "Q7ZW47-1", "name": "Double-stranded RNA-binding protein Staufen homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANPKEKTPMCLVNELARFNRIQPQYKLLNEKGPAHAKIFTVQLCLGNQVWESEGSSIKKAQHSTATKALAESSLPRPPPRSPKADSNSNPG-------SITPTVELNGLAMKRGEPAIYRPLD-------------------------------------------------PKPIPNYRANYNFRG-MFNQR----YHYPVP------------------KVFYVQLTVGNNEFIGEGRTRQAARHNAAMKALQALKNEPIPERPPQCSEEKKETEENSDASKSEISLVYEIALKRNLPVNFEVLKESGPPHMKSFLTRVTVGEFSAEGEGNSKKLSKKRAALSILQELKKLPVLPVVEKPKVHYKKRPKT-----------ILK--TGPEYG--------------------QGMNPISRLAQIQQAKKEKEPEYMLLSERG--MPRRREFIMQVKVGTEVTTGTGPNKKVAKRNAAEAMLLQLGYKAS-----TPLQN-------------------TPEKMD-NKGWNGQRAAFPETTSNTQKG-------ILHLSPDVYQEMEASRNKGVPGAPGNFPTAKEIGQGSAGPFCTP---SVGNTATIAKELLLSGTSPTAEALVLKGKAP--ALACGSIQPS---------------QQLEYLAHIQGFQVQYSDRQTDKEFMTYLTLSPVQMTFHGIGSSIPASHDQAALSALKQLSEQGLDPVDGPIKVENGSCDIQAKRLAERTESKPTNSGTTAQDCKDSKAVV--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95793-1", "uniprot_id": "STAU1_HUMAN", "id": "O95793-1", "name": "Double-stranded RNA-binding protein Staufen homolog 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPS----ASIT--------------------------------------------------------------------------STSAAAESITP---------------------------TVELNALCMKLGKKPMYKPVD-------------------------------------------------PYSRMQSTYNYNMRGGAYPPR----YFYPFP---------------VPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRE----SEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKP-----------IVKPQTSPEYG--------------------QGINPISRLAQIQQAKKEKEPEYTLLTERG--LPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALK-------------------SEEKTPIKKPGDGRKVTFFEPGSGDENG-TSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR-AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPS---------------EQLDYLSRVQGFQVEYKDFPKN---------------------------NKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z108-1", "uniprot_id": "STAU1_MOUSE", "id": "Q9Z108-1", "name": "Double-stranded RNA-binding protein Staufen homolog 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYKPVD-------------------------------------------------PHSRMQSTYSYGMRGGAYPPR----YFYPFP---------------VPPLLYQVELSVGGQQFNGKGKMRPPVKHDAPARALRTLQSEPLPERLEVNGRE----AEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTRVSVGEFVGEGEGKSKKISKKNAARAVLEQLRRLPPLPAVERVKPRIKKKSQP-----------TCK--TAPDYG--------------------QGMNPISRLAQIQQAKKEKEPEYMLLTERG--LPRRREFVMQVKVGHHTAEGVGTNKKVAKRNAAENMLEILGFKVPQAQPAKPALK-------------------SEEKTPVKKPGDGRKVTFFEPSPGDENG-TSNKDEEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR-AAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHVPHGPRTRPS---------------EQLYYLSRAQGFQVEYKDFPKN---------------------------NKNECVSLINCSSQPPLVSHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPVSACGRC-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JQK6-1", "uniprot_id": "A0AC58JQK6_DANRE", "id": "A0AC58JQK6-1", "name": "Double-stranded RNA-binding protein Staufen homolog 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLQFQAPGNPAPSSAPLQLAP-----PQPGFSIPCGTAPLPSESASHPLRNSALPS----ASATPFCNPTVSNMANPKEKTPMCLVNELARYNKIQPEYKLLSEEGPAHSKIFSVRLTLGDQHWDAEGTSIKKAQHSAASSALAQTTLPKPSHRSPRHPGKSPGGIYKGSEYNVTHTVELNALCMKLGKKPIYKPID-------------------------------------------------AYQGMRPAFNYNIRAPSPYARSMQHYYYPFPP--------------VGPVLYHMELSIGGQQFHGKGRTRQAAKHDAAAKAIKYLQKEPILQQITEMTDE----PAQENLNKSEISQVFEIALKRNMPVDFEVLKEAGAPHMKSFVVRVVVGEFAGEGEGKSKKIAKKQAAIAVLEELRRLPQLPATDKIPLRIKKKSKS-----------IIKLQTSPEYG--------------------QGMNPISRLAQIQQAKKEKEPEYTLVTERG--LPRRREFVMQVSVAGQNAEGMGPSKKVAKRNAAEKMLELLGFKVPQPQPPKPALK-------------------TDEKPPAKKLGDGRKVTFFEPGSMEKAGLVVSKEEDFRLPFLSHQQLPAGILPMVPEVAQAVGANQGPHAKDYGRTAAPNPANATVTAMIANELLYAGTSPTAEGILKTNNSLAHRPQGPLTRPS---------------EQLSYLANVQGLQVEYKDFPKN---------------------------NKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSNE--RTANGPMSGSVSCLQVFYVLIILQYKLVVLGLSRYWNSGPIVISVEHVNTMANQRCLRKYSVALKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25159-1", "uniprot_id": "STAU_DROME", "id": "P25159-1", "name": "Maternal effect protein staufen", "aln": "MQHNVHAARPAPHIRAAHHHSHSHAHMHLHPGMEQHLGPSLQQQQQPPPPPQQPPHRDLHARLNHHHLHAQQQQQQQTSSNQAGAVAAAGAAYHHGNINSNSGSNISSNSNQMQKIRQQHQHLSSSNGLLGNQPPGPPPQAFNPLAGNPAALAYNQLPPHPPHHMAAHLGSYAAPPPHYYMSQAKPAKYNHYGSNANSNSGSNNSNSNYAPKAILQNTYRNQKVVVPPVVQEVTPVPEPPVTTNNATTNSTSNSTVIASEPVTQEDTSQKPETRQEPASADDHVSTGNIDATGALSNEDTSSSGRGGKDKTPMCLVNELARYNKITHQYRLTEERGPAHCKTFTVTLMLGDEEYSADGFKIKKAQHLAASKAIEETMYKHPPPKIRRSEEGGPMR------THITPTVELNALAMKLGQRTFYLLDPTQIPPTDSIVPPEFAGGHLLTAPGPGMPQPPPPPAYALRQRLGNGFVPIPSQPMHPHFFHGPGQRPFPPKFPSRFALPPPLGAHVHHGPNGPFPSVPTPPSKITLFVGKQKFVGIGRTLQQAKHDAAARALQVLKTQAISASEEALEDS-----MDEGDKKSPISQVHEIGIKRNMTVHFKVLREEGPAHMKNFITACIVGSIVTEGEGNGKKVSKKRAAEKMLVELQKLPPLTPTKQTPLKRIKVKTPGKSGAAAREGSVVSGTDGPTQTGKPERRKRLNPPKDKLIDMDDADNPITKLIQLQQTRKEKEPIFELIAKNGNETARRREFVMEVSASGSTARGTGNSKKLAKRNAAQALFELLEAVQVTPTNETQSSEECSTSATMSAVTAPAVEATAEGKVPMVATPVGPMPGILILRQNKKPAKKRDQIVIVKSNVESKEEEANKEVAVAAEENSNNSANSGDSSNSSSGDSQATEAASESALNTSTGSNTSGVSSNSSNVGANTDGNNHAESKNNTESSSNSTSNTQSAGVHMKEQLLYLSKLLDFEVNFSDYPKG---------------------------NHNEFLTIVTLSTHPPQICHGVGKSSEESQNDAASNALKILSKLGLNNAMK-------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . :. : : * * : * :* ::* * *: .:*:*. :*:: *:.:.: . :.. .** ** *.**.:***:.* *:* :* *..***.*:. **.: ****:.**::**.** :* :*::** *. .: * . . .* :. ***::* *:**::***** : *:::.* .*****:*:*... : * * .**:**:***: :: * . . * * : . .: :: . . . . : : *.*. :. : . . ..* :** **:. .: : :: * : .* : : . : * . : .. ", "identical_positions": 93, "similar_positions": 124, "identity": "8.22%" }, { "cls_id": "homologset.agr.FB:FBgn0003525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48966-1", "uniprot_id": "MPIP2_RAT", "id": "P48966-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPPQKSAPGSALSTARVLGGIQRPRHLSGFGFGSDGLLGSPERAASSSPVTTLTQTMYNLAGLGSETPKTQVGSLSFQN--RLTDLSLSRRTSECSLSSESSESSDAGLCMDSPSPMDPQTAERTFEQAIQAASRVIQKMQFTIKAS-VFASEAAGHSPVLQ-NITNSQALDSWEKDEAGYRAAS-SPGEDKENDGYIFKMPQKLPHSSSARALAEWASRREAFTQRPSSAPDLMCLTTDGK-MDVEEASPVAQ-SSSLTPVERACEEDDGFVDILES-DLKDDDMVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSPSMPCSV---IRPILKRLERPHDRDVPVLSKRRKSG--TPLEEQQ-LEEPKARVFRSKSLCH-----EIESILDSDHRGLIGDYS--------------------KAFLLQTVDGKHQDLKYISPETMVALLTG-KFSNIVEKFVIVDCRYPYEYEGGHIKNAVNLPLEPDAETFLLKH-------------------PITPCNLDKRIILIFHCEFSSERGPRMCRFIR--ERDRAANDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHAA----FRDELRNFRLKTRSWAGERSTTQLCSRLQDQ---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30306-1", "uniprot_id": "MPIP2_MOUSE", "id": "P30306-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPLQKSAPGSALSPARVLGGIQRPRHLSVFEFESDGFLGSPEPTASSSPVTTLTQTMHNLAGLGSEPPKAQVGSLSFQN--RLADLSLSRRTSECSLSSESSESSDAGLCMDSPSPVDPQMAERTFEQAIQAASRVIQNEQFTIKRFRSLPVRLLEHSPVLQ-SITNSRALDSWRKTEAGYRAAANSPGEDKENDGYIFKMPQELPHSSSAQALAEWVSRRQAFTQRPSSAPDLMCLTTEWK-MEVEELSPVAQ-SSSLTPVERASEEDDGFVDILES-DLKDDEKVPAGMENLISAPLVKKLDKEEEQDLIMFSKCQRLFRSPSMPCSV---IRPILKRLERPQDRDVPVQSKRRKSV--TPLEEQQ-LEEPKARVFRSKSLCH-----EIENILDSDHRGLIGDYS--------------------KAFLLQTVDGKHQDLKYISPETMVALLTG-KFSNIVEKFVIVDCRYPYEYEGGHIKNAVNLPLERDAETFLLQR-------------------PIMPCSLDKRIILIFHCEFSSERGPRMCRFIR--ERDRAANDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEA----FRDELRNFRLKTRSWAGERSRRELCSRLQDQ---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30305-1", "uniprot_id": "MPIP2_HUMAN", "id": "P30305-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLR-NITNSQAPDGRRKSEAGSGAAS-SSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRK-MEVEELSPLALGRFSLTPAEGDTEEDDGFVDILES-DLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSV---IRPILKRLERPQDRDTPVQNKRRRSV--TPPEEQQEAEEPKARVLRSKSLCHD----EIENLLDSDHRELIGDYS--------------------KAFLLQTVDGKHQDLKYISPETMVALLTG-KFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKS-------------------PIAPCSLDKRVILIFHCEFSSERGPRMCRFIR--ERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEA----FKDELKTFRLKTRSWAGERSRRELCSRLQDQ---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48964-1", "uniprot_id": "MPIP1_MOUSE", "id": "P48964-1", "name": "M-phase inducer phosphatase 1", "aln": "MELGPEPPHRRRLFFACSPT---PAPQPTGKMLFGAS-------AAGGLSPVTNLTVTMDQLEGLGSDCEK------------------MEVRNNSSLQRMGSSESTDSGFCLDSPGPLDSK-----------------ENLEISLTRINSLPQKLLGCSPALKRSHSDSLDHDTFHLIDQ---------DENKENEAFEFKKPIRPASR-----HIYEESK-DPFTHRQNSAPARMLSSNES---ESGNFSPLFIPQSPVK--ATLSDEDDGFIDLLDGENMKNDEETPSCMASLWTAPLVMRRPANLAD------RCG-LFDSPSPCGSS---TRAVLKRADRSHEEPPRG-TKRRKSVPSPVKAKADVPEPAQLP-SQSLSLMSSPKG-TIENILDSDPRDLIGDFS--------------------KGYLFNTVSGKHQDLKYISPEIMASVLNG-KFAGLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKN-------------------PIVPTD-GKRVIVVFHCEFSSERGPRMCRYVR--ERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHED----FKEDLKKFRTKSRTWAGEKSKREMYSRLKKL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48965-1", "uniprot_id": "MPIP1_RAT", "id": "P48965-1", "name": "M-phase inducer phosphatase 1", "aln": "MELGPEPPHRRRLLFTCSPT---PAPQPTGKVQFGAS-------RAGGLSPVTNLTVTMDQLEGLGSDYEKP-----------------MDVRNSSSLQRMGSSESTDSGFCLDSPGPLDSK-----------------ENLEISLRRINCLPQKLLGCSPALKRSHSDSLDHDIFQLIDQ---------DENKENEAFEFKKPIRPASRGCLNAHVHEESK-DPFTHRQNSAPARMLSSNESDISESGNFSPLFTPQSPVK--ASLSDEDDGFIDLLDGENLKNDEETPSCMSSLWTAPLVMRRPTNLAD------RCG-LFDSPSPCSSTSSCSTRAVKRADRSHEESPRG-TKRRKSS-EASPVKADVPEPTQLP-HQSLSLTSFPKG-TIENIFHSDPRDLIGDFS--------------------KGYLFHTVSGKHQDLKYISPEIMASVLNG-KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEEFLLKK-------------------PIVPAD-GKRVIVVFHCEFSSERGPRMCRYVR--ERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHED----FKEDLKKFRTKSRTWAGEKSKREMYSRLKKL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30304-1", "uniprot_id": "MPIP1_HUMAN", "id": "P30304-1", "name": "M-phase inducer phosphatase 1", "aln": "MELGPEPPHRRRLLFACSPP---PASQPVVKALFGAS-------AAGGLSPVTNLTVTMDQLQGLGSDYEQP-----------------LEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSK-----------------ENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDP---------DENKENEAFEFKKPVRPVSRGCLHSHGLQEGK-DLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVT--ATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMR-TTNLDN------RCK-LFDSPSLCSSS---TRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKG-TIENILDNDPRDLIGDFS--------------------KGYLFHTVAGKHQDLKYISPEIMASVLNG-KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKK-------------------PIVPTD-GKRVIVVFHCEFSSERGPRMCRYVR--ERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHED----FKEDLKKFRTKSRTWAGEKSKREMYSRLKKL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48967-1", "uniprot_id": "MPIP3_MOUSE", "id": "P48967-1", "name": "M-phase inducer phosphatase 3", "aln": "MSTGPIPPASEEGSFVSAPSFRSKQRKILHLLLERNTSFTIR--SDFPESPKDK-LHDSANLSILSGGTPKC------------------CLDLSNLSSGEMSASPLTTSADLEDNGSLDSS-----------------GPLDRQLTGKDFHQDLMKGIPVQLLCSTPNAMNHG---------------------------------------------------HRKKIAKRSTSAHKEN-----INTSLKALEWEAPRTPRFRKMP--GGPLTSPLC--ELE--------MKHLGSP----------------------ITTVPKLSQNVK------LEDQERISEDPMECSLGD--------------QDAKGLSLRKMVPLCDMNAI-QMEEE-ESGSELLIGDFS--------------------KVCVLPTVPGKHPDLKYISPDTVAALLSG-KFQSVIERFYIIDCRYPYEYLGGHILGALNLHSQKELHEFFLRK-------------------PVVPLDIQKRVIIVFLCEFSSERGPRMCRSLR--EKDRALNQYPALYYPELYILKGGYRDFFPEYMELCDPQSYCPMLHQD----HQAELLSWRSQSKAQEGERQLQGQIALLVKGASPQ-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LL59-1", "uniprot_id": "A0ABK0LL59_RAT", "id": "A0ABK0LL59-1", "name": "M-phase inducer phosphatase", "aln": "MSTVPFPAASEEGSYVSAPSFRFKQRKMLHLLLERHASFTVG--SDFPESPGDK-LHDSANLSLLSGGTPKC------------------CLDLSSLSNGEVSASHLSTSADIEENGSLDSS-----------------GPQDIHLTGKDFHQDLMKGIPAQLLCSTPNALDHG---------------------------------------------------HRRKDAKCSTSANKEN-----INTSFKTLEWEAPRTPRLQKKP--GDPLASPLC--ELENGILLESEMKNLGSP----------------------ITTVPKLSKNLK------LEDQEGISEDPMECSLED--------------QDAKGLSLKKTVPLCGMDAI-ELEEE-DSDSEHLTGDFSKIVFRNSGSFCINRPAARIVEACVLPTVPGKHQDLKYISPDTVAALLSG-KFQSVIERFYIIDCRYPYEYLGGHILGALNLYSQKELYEFFLKK-------------------PVVPEDTQKRVIIVFLCEFSSERGPRMCRSLR--EKDRALNQYPALYYPELYILRGGYRDFFPEYMELCEPQGYCPMLHQD----HQAELLSWRSQSKAQEGERQLREQIALLVKNVSPQ-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30307-1", "uniprot_id": "MPIP3_HUMAN", "id": "P30307-1", "name": "M-phase inducer phosphatase 3", "aln": "MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVC--PDVPRTPVGKFLGDSANLSILSGGTPKR------------------CLDLSNLSSGEITATQLTTSADLDETGHLDSS-----------------GLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRG---------------------------------------------------HRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISD-ELMEFSLKDQEAKVSRSG----------------------LYRSPSMPENLNR---PRLKQVEKFKDNTIPDKVKKKYFS-------GQGKLRKGLCLKKTVSLCDITIT-QMLEE-DSNQGHLIGDFS--------------------KVCALPTVSGKHQDLKYVNPETVAALLSG-KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK-------------------PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLR--EEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQD----HKTELLRCRSQSKVQEGERQLREQIALLVKDMSP------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z595-1", "uniprot_id": "A0A8M6Z595_DANRE", "id": "A0A8M6Z595-1", "name": "protein-tyrosine-phosphatase", "aln": "MAGDALEICDLT---------------------------------AEDSSPVNELSFRLQNLQCQDGLSPKR----------------------STPRKLVLTPECMSSSLNTLS---------------------------------------REKETPTVRRRRASRSLSPE---------------------------------------------------STSNTPRCPLRNNQDFPANKENERAIKRLRVRLSSRFSSSNATETAGRNRRQYRS----------------------------------------------------------------DPEEDATPSRETEAVDP------------MAAVRFRQLMSQLQAPPT-PVTQVAVADLT-LIGDFS--------------------KQHLLPVESAGHQEHHCISAQTVASLIRG-QFGSAVEDFLIVDCRYPYEYQGGHIKGAVNLYTEHQVQQVLHQASAQVSVSTSRLCGRSASDSLPEDEESPSRKLIIFHCEFSSERGPHLCQYLR--RLDRCVNVYPSLHYPELYLLLGGYKHFHASYPDLCDPCGYVSMRQRE----YREQLNSFLRRRQTRQRRRRPIRRHHRTKR----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20483-1", "uniprot_id": "MPIP_DROME", "id": "P20483-1", "name": "M-phase inducer phosphatase", "aln": "-MLWETIVEENNCSMDCNISNNTSSSSSINKMSGSRR----------ARRSLELMSMDQEELSFYDDDVVPQD----------------QQRSASPELMGLLSPEGSPQRFQIVRQPKILPAMG-----------------VSSDHTPARSFRIFNSLSSTCSMESSMDDEYMELFEMESQ--------------------------------------------SQQTALGFPSGLNSLISGQIKEQPAAKSPAGLSMRRPSVRRCLSMTESNTNSTTTPPPKTPETARDCFKRPEPP-------------------------ASANCSPIQ----SKRHRCAAVEKENCPAPSPLSQVT-----------ISHPPPLRKCMSLNDAEIMSALARSENRNEPELIGDFS--------------------KAYALPLMEGRHRDLKSISSETVARLLKG-EFSDKVASYRIIDCRYPYEFEGGHIEGAKNLYTTEQILDEFLTVQQTELQQ------------QQNAESGHKRNIIIFHCEFSSERGPKMSRFLRNLDRERNTNAYPALHYPEIYLLHNGYKEFFESHVELCEPHAYRTMLDPA----YNEAYRHFRAKSKSWNGD-GLGGATGRLKKSRSRLML---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23748-1", "uniprot_id": "MPIP_YEAST", "id": "P23748-1", "name": "M-phase inducer phosphatase", "aln": "MNNIFHGTEDECANEDVLSFQKISLKSPFGK-------------KKNIFRNVQTFFKSKSKHSNVDDDLINKE---------------NLAFDKSPLLTNHRSKEIDGPSPNIKQLGHRDELD------------------------------ENENENDDIVLSMHFASQTLQ------------------------------------------------------SPTRNSSRRSLTNNRDNDLLSRIKYPGSPQRSSSFSRSRSLSRKPSMNSSSN-----------------------------------------------------------SSRRVQRQDGKIPRSSRKSSQK----------FSNITQNTLNFTSASSSPLAPNSVGVKCFESCLAKTQIP-----------------------YYYDDRNSNDFFPRISPETLKNILQNNMCESFYNSCRIIDCRFEYEYTGGHIINSVNIHSRDELEYEFIHKVLH----------------SDTSNNNTLPTLLIIHCEFSSHRGPSLASHLRNCDRIINQDHYPKLFYPDILILDGGYKAVFDNFPELCYPRQYVGMNSQENLLNCEQEMDKFRRESKRFATKNNSFRKLASPSNPNFFYRDSHQSSTTMASSALSFRFEPPPKLSLNHRRVSSGSSLNSSESTGDENFFPILSKSSMSSNSNLSTSHMLLMDGLDTPSYFSFEDERGNHQQVSGDEEQDGDFTFVGSDREDLPRPARRSLFPSLETEDKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : . . . . : . : :..: : :: . . ::***: **: **** : *: : : . :::: *****.*** :. :* : ** *.**:: :* .**: .. . . * * * * . . : ", "identical_positions": 31, "similar_positions": 52, "identity": "4.01%" }, { "cls_id": "homologset.agr.FB:FBgn0003545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97329-1", "uniprot_id": "KI20A_MOUSE", "id": "P97329-1", "name": "Kinesin-like protein KIF20A", "aln": "MSHRILSPPAGLLSDEDVVDSPILESTAADLRSVVRKD----LLSDCS-VISASLE--------------DKQ-ALLEDTSEKVKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKDSFALKSNERGVGQATHKFTFSQIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQGTSKDAGILPQSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLIGGLQEEELSTSVKKRVHTESRIGASNSFDSGVAGLSSTSQFTSSSQLDETSQLWAQPDTVPVS----VPADIRFSVWISFFEIYNELLYDLLEPPS-----HQHKRQTLRLCEDQNGNPYVKDLNWIHVRDVEEAWKLLKVGRKNQSFASTHMNQQSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKHQ-KSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQ-NLIPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHAAKFSALASQLVHAPPVHLGIPSLHSFIKKHSPQVGPGLEKEDKADSDLEDSPEDEADVSVYGKEELLQVVEAMKALLLKERQEKLQLEIQLREEICNEMVEQMQQREQWCSERLDNQKELMEELYEEKLKILKESLTTFYQEQIQERDEKIEELETLLQEAKQQ-PAAQQS----GGLSLLRRSQRLAASAS------TQQFQEVKAELEQCKTELSS-------TTAELHKYQQVLKPPPPAKPFTIDVDKKLEEGQKNIRLLRTELQKLGQSLQSAERACCHSTGAGKLRQALTNCDDILIKQNQTLAELQNNMVLVKLDLQKKAACIAEQYHTVLKLQGQASAK----KRLGANQENQQPNHQPPGKKPFLRNLLP-RTP-------TCQSSTDSSPYARILRSRH-SPLLKS-PFGKKY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95235-1", "uniprot_id": "KI20A_HUMAN", "id": "O95235-1", "name": "Kinesin-like protein KIF20A", "aln": "MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKN----LLSDCS-VVSTSLE--------------DKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLP----VPANIRFSIWISFFEIYNELLYDLLEPPS-----QQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQ-KSGERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQ-NLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQS----GSELALRRSQRLAASAS------TQQLQEVKAKLQQCKAELNS-------TTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAK----KRLGTNQENQQPNQQPPGKKPFLRNLLP-RTP-------TCQSSTDCSPYARILRSRR-SPLLKSGPFGKKY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDF0-1", "uniprot_id": "F1QDF0_DANRE", "id": "F1QDF0-1", "name": "Kinesin-like protein", "aln": "---MALASPCGILSDEEECG-AVFESTAADVVGLMRSQRFVSPLPEIS-VITPAADSLTPTKELVQIKSDISRRGSTDDGSDKLKVFLRIRPLTEAEKDRGEEQGCVNVQSEDNLLLKAPKDSRNMKSAERGVAQSVHKFTFTKIFGPQTSQQEVYDHTIREMVRDVLRGENRLLYTYGVTNSGKTYTIQGAGAEAGLLPRALVSVFLKLSGRLYTAMDLKPVLSQEVRKLDVGEVRAEEMRRDALLK----EDESN---------QSRLRAGLSWDSGISGLSATSHIAT--QLEDSDGVCLEANGLCLSGGEDLEEGVQFSVWVSFYEIYNEFLYDLLDAPPS---LQSRKRVTLRLSDDKHGNPYVKDLTWIQVHSAEEAWKVLKVGQRNQSFASTHLNHNSSRSHSIFTIRVLHVKPQLGQVTRISELSVCDLAGSERCKAQ-QNGERMKEANNINTSLLTLGRCITALRHNQTNKSRPPVVVPFRDSKLTRVLQSFFCGHGRSCMVVNINPCASTYDETLQALKFSAIATQLVHGPCSKTRVAYILSLLREQ-----PTHPNDTTLLEEDEEESDEEGDITMFDPEALLKAIDVLKREVLRQRQEKEELEAKVREEVCTEMMEVISRMQDDFSETLESERDLMEKRCENKINNLKSSLKKYYSQELEERDDEIRELTAALKEKEAGNTAPAAIFPPLNDDGGLRRSQRLASTHKRDADHESIELFRCKAELENCRAELDLKQTELRLKTLELKRFQDNLPSMGVTGTLTTTAERKLEEGQRNLKQLRMELQLLGIKLQSGERACCRNTDGEKLRHALSSADSKLAKQDQMLVELHTSLQLVKAELRKKDELLTRFQNTQQAQSHQPPTASGSCKKRGCGVAVALAENQPPEKRPFFRSLFPSRTPSKTPSRPTRQQNEVTTPYSRVLRSRQPSPPTTPVMLRVKY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V877-1", "uniprot_id": "SUB_DROME", "id": "Q9V877-1", "name": "Kinesin-like protein subito", "aln": "----MDSKEVSEVPRREVRSFLMARDPSIDRRFRPRPNKKMRLFDNIQESEEESFSEYSDTESEYKYQSSEATEGASCATSAADSSNVETGPQVFLRLRPVKDASKAYIVSEEANVLIT---SCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIYDTCVG---PKIMEEECVTIMTYGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCP---------------------------------DISAHHQRLKQVIDGDHMFETKASTDVS----------VLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNK-GHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSG--ITTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNAD--IIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYCGFMEFS-----------------KMSTCEGGDYTKELEDENVRLQLEIEQLKYDHVLQMQLLEEKLRRELTATYQEIIQ-----------NNKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLKDEIEELKNPAS--------------------------------------------------------------------------------DTDISDDPNESKSPIEILDDD------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. : : ...: * * : : : . : . . :. * . :: . . : . : :* : * :.* ...: : ::* *:.**.. ..* .:: : .::. : : ***.:.****:*: * .*::*::* :* .. :. : .** : .. * * .:: :::: * . :: *: : . :. . :*:** *****::**** *. . * .*:: :: *: ::*.*. : * . *** ::*::*::..::*** :* :*****.:*:: :*: : . :. *. ..******** : .* *:*** ****** .****: * * ::. ::*:****** ::*. : *: : .*:*.:.* . *:*.*:. :*:::*.:::. . : : . . : .* : : :: :: . : ** ::* *: * :. .::. *. *:*: : . ..: .. :::*.:* ::* . . . :*.: :. * : ", "identical_positions": 122, "similar_positions": 219, "identity": "12.84%" }, { "cls_id": "homologset.agr.FB:FBgn0003557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FIK1-1", "uniprot_id": "F7FIK1_RAT", "id": "F7FIK1-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "MSSLTEEIASSSSSYPQCLEQFLVHKFQFWALQTCFSYYSICHNQGEFWDMATASPRSDTSDNHSG-RLQLKVTVSSAKLKR-KKNWFGTAIYTEVIVDG---EIKKTAKSSSSSNPKWDEQLIVN-VAPQTTLEFRVWSHHTLKA--DALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENKNGIVQT--GELTVVLDGLVIEPEAVTNRSSSPPIE---------------------------------------IQQNGDAVHENGDPLTRTTPRLAVEGTIG-IDNHVSTSTVVPSSCCSHIVNGE---NTPSSPPQVATRPQNTPAPKPLTSEPTSDTVNGESSS-VLADSTSAMGTSLPS------------EDSTSTSNCTSTTVQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPD-SDSRNNSGFD--KVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYS----------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG----------------LPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTK--GGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZZ3-1", "uniprot_id": "WWP1_MOUSE", "id": "Q8BZZ3-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "--------------------------------------------------MATASPRSDTSDIHSG-RLQLKVTVSSAKLKR-KKNWFGTAIYTEVIVDG---EVKKTAKSSSSSNPKWDEQLIVN-VTPQTTLEFRVWSHHTLKA--DALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENKNGIVQT--GELTVVLDGLVIEQEPVTNRSSSPPIE---------------------------------------IQQNGDALHENGDPATRTTPRLPVEGTIG-IDNHVSTNTVVPNSCCSHVVNGE---NTPSSPSQVAARPKNAPAPKPVTSAPTSDTVNGESSS-VLADNTSTMGTLLPS------------EDTTSTSNCTSTTTQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPD-SDSRNNSVFD--KVRQPEGCVEPLRPQSGNTNTEALPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYS----------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG----------------LPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTK--GGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0M0-1", "uniprot_id": "WWP1_HUMAN", "id": "Q9H0M0-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP1", "aln": "--------------------------------------------------MATASPRSDTSNNHSG-RLQLQVTVSSAKLKR-KKNWFGTAIYTEVVVDG---EITKTAKSSSSSNPKWDEQLTVN-VTPQTTLEFQVWSHRTLKA--DALLGKATIDLKQALLIHNRKLERVKEQLKLSLENKNGIAQT--GELTVVLDGLVIEQENITNCSSSPTIE---------------------------------------IQENGDALHENGEPSARTTARLAVEGTNG-IDNHVPTSTLVQNSCCSYVVNGD---NTPSSPSQVAARPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVS------------EENALSPNCTSTTVEDPPVQEILTSSENNECIPSTSAELESEARSILEPDTSNSRSSSAFEAAKSRQPDGCMDPVRQQSGNANTETLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRRRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYS----------ASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQG----------------LQNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTK--GGPQIAYERGFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBH0-1", "uniprot_id": "WWP2_MOUSE", "id": "Q9DBH0-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "aln": "--------------------------------------------------MASASSSRAGVALPFE-KSQLTLKVVSAKPKV-HNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIVLN-VTAQSHLDLKVWSCHTLR---NELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGSVVSG--GELTIFLDGPTVDLGSVPNGSAVTDGS---------------------------------------QPPSRESSGTAIAPETRHQP----PSTNC-FGGRSRTHRHSGGSARTATAASE---QSPG-----ARNRHRQPVKNSSSSGLANGTVNEEPTPASEPEESSVVGVTSLP------------AAALSVSSNPNTTS----LPAQSTPAEGEEASTSGTQQLPAAAQ--------------------------------------APDALPAGWEQRELPNGRVYYVDHNTKTTTWER--PLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQ----------SSSASTDHDPLGPLPPGWEKRQD-NGRVYYVNHNTRTTQWEDPRTQG----------------MIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTK--QGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELFFIQDMEILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B4F767-1", "uniprot_id": "B4F767_RAT", "id": "B4F767-1", "name": "E3 ubiquitin-protein ligase", "aln": "--------------------------------------------------MASASSSRAGVALPFE-KSQLTLRVVSAKPKV-HNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEVIVLN-VTAQSHLDLKVWSCHTLR---NELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGSVVSG--GELTIFLDGPTVDLGSVPNGSAVTDGS---------------------------------------QPPSRESSGTALAPETRHQP----PSTNC-FGGRSRTHRHSGGSARTATATGE---QSPG-----ARNRHRQPVKNPSSSGLANGTVSEEPTTASDPEELSVVGVTSPP------------AAASSVSPNPNTTS----LPAPSTPAEGEEPSTSGTQQLPAAAQ--------------------------------------APDALPAGWEQRQLPNGRVYYVDHNTKTTTWER--PLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQ----------SSSASTDHDPLGPLPPGWEKRQD-NGRVYYVNHNTRTTQWEDPRTQG----------------MIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTK--QGSPGAYERSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLRDLESIDPEFYNSIIWIKENNLDECGLELFFIQDMEILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00308-1", "uniprot_id": "WWP2_HUMAN", "id": "O00308-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "aln": "--------------------------------------------------MASASSSRAGVALPFE-KSQLTLKVVSAKPKV-HNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILN-VTAQSHLDLKVWSCHTLR---NELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSG--GELTIFLDGPTVDLGNVPNGSALTDGS---------------------------------------QLPSRDSSGTAVAPENRHQP----PSTNC-FGGRSRTHRHSGASARTTPATGE---QSPG-----ARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPP------------AAPLSVTPNPNTTS----LPAPATPAEGEEPSTSGTQQLPAAAQ--------------------------------------APDALPAGWEQRELPNGRVYYVDHNTKTTTWER--PLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQ----------SSSASTDHDPLGPLPPGWEKRQD-NGRVYYVNHNTRTTQWEDPRTQG----------------MIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTK--QGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEGFGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C863-1", "uniprot_id": "ITCH_MOUSE", "id": "Q8C863-1", "name": "E3 ubiquitin-protein ligase Itchy", "aln": "--------------------------------------------------MSDSGPQLDSMGSLTM-KSQLQITVISAKLKENKKNWFGPSPYVEVTVDG---QSKKTEKCNNTNSPKWKQPLTVI-VTPTSKLCFRVWSHQTLKS--DVLLGTAGLDIYETLKSNNMKLEEVVMTLQLVGD-KEPTETM--GDLSVCLDGLQVEAEVVTNGETSCSES-----------------------------------------TTQNDDGCRTRDDTRVSTN---GSEDP-EVAASGENKRANGNNSPSLSNGG---FKPS--------RPPRPSRPPPPTPRRPASVNGSPSTNSDSDG-SSTGSLPPT------------NTNVNTSTSEGATSG---LIIPLTISGG-----SGPRPLNTVSQ----------------------------------------APLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQD-----LFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQG----------------QLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTG-KSALD--NGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K9T1-1", "uniprot_id": "A0A0G2K9T1_RAT", "id": "A0A0G2K9T1-1", "name": "E3 ubiquitin-protein ligase", "aln": "--------------------------------------------------MSDSAPQLDSMGSLTM-KSQLQITVISAKLKENKKNWFGPSPYVEVTVDG---QSKKTEKCNNTNSPKWKQPLTVI-VTPMSKLCFRVWSHQTLKS--DVLLGTAGLDIYETLKSNNMKLEEVVMTLQLVGD-KEPTETM--GDLSVCLDGLQVEAEVVTNGETSCSEG-----------------------------------------ATQNDAGCRPKDETRVSTN---GSEDP-EVAASGENKRANGNNSPSLSNGG---FKPS--------RPPRPSRPPPPTPRRPASVNGSPSTNSDSDG-SSTGSLPPT------------NTNVNSSASEGAASG---LIIPLTISGG-----SGPRPLNTVSQ----------------------------------------APLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIFGNQD-----LFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQG----------------QLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTG-KSALD--NGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIVWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96J02-1", "uniprot_id": "ITCH_HUMAN", "id": "Q96J02-1", "name": "E3 ubiquitin-protein ligase Itchy homolog", "aln": "--------------------------------------------------MSDSGSQLGSMGSLTM-KSQLQITVISAKLKENKKNWFGPSPYVEVTVDG---QSKKTEKCNNTNSPKWKQPLTVI-VTPVSKLHFRVWSHQTLKS--DVLLGTAALDIYETLKSNNMKLEEVVVTLQLGGD-KEPTETI--GDLSICLDGLQLESEVVTNGETTCSENGVSLCLPRLECNSAISAHCNLCLPGLSDSPISASRVAGFTGASQNDDGSRSKDETRVSTN---GSDDP-EDAGAGENRRVSGNNSPSLSNGG---FKPS--------RPPRPSRPPPPTPRRPASVNGSPSATSESDG-SSTGSLPPT------------NTNTN--TSEGATSG---LIIPLTISGG-----SGPRPLNPVTQ----------------------------------------APLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQD-----LFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQG----------------QLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTG-KSALD--NGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0H4-1", "uniprot_id": "SUDX_DROME", "id": "Q9Y0H4-1", "name": "E3 ubiquitin-protein ligase Su(dx)", "aln": "--------------------MADGNGLPAGAASGGMEAGQTVNGAGSASPTPTSSSGAGASGSANQGYHQLSVTIEEASLRN--NGFLKPNPYVELLIDS--KSKRKTDLVKNSYLPKWNEEFTVL-ITPNSTLHFKVLDHSSFRK--DAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLKLDMSKLQIQPVAGQQNG--------------------------------------NPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYLPAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQP------------------------------------ADDEPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQR---AHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQE------------VSLINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39940-1", "uniprot_id": "RSP5_YEAST", "id": "P39940-1", "name": "E3 ubiquitin-protein ligase RSP5", "aln": "--------------------------------------------------MPSS----------------ISVKLVAAESLYKRDVFRSPDPFAVLTIDG--YQTKSTSAAKKTLNPYWNETFKFDDINENSILTIQVFDQKKFKKKDQGFLGVVNVRVGDVLGHLD------EDTATSSGRPREETITR---DLKKSNDGMAVSGRLIVVLSKLPSSS----------------------------------------PHSQAPSGHTASSST-----------------NTSSTTRTNGHSTSSTRNHS--------------------------------TSHPSRGTAQAVESTLQSGTTAAT------------NTATTSHRSTNSTS-------------------SATRQYSSFED--------------------------------------QYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKR-----PTLDQTEAERGNQLNANTELERRQHRGRTLPGGSSDNSSVTVQVGGGSNIPPVNGAAAAA----------FAATGGTTSGLGELPSGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPTNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQN-----VPQYKRDFRRKVIYFRSQPALRILPGQCHIKVRRKNIFEDAYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDGV-LDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIGFGQE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : *. . :. : :*. . .* : *.: : . : : * ::* . .:: : :** : : . * . : :* :* :. : . : . : . .:: * . **.*** * ** ***** : * *.: * : . .: . : . : : : . . * ** ***:: .*.*:*:*:.: * * *** * : .** ***:: * . :***** : **: *** . * *.*: * ** :* : :*.* *:.:***::::** . :*::** : : *********::**:*******::**:******: :** :**** * :**:** ** ****.:.:.::* :*: : * .:** :* * ::*:* :*.*.***: *: :*.:: *:: * * * :*:: :** .* . **: **.**: : ::**: :::* ::*::****: * : : ** :***::: *: ::*: **:: : ** * ...: : ***: * * *** * *****.***.*:*:.** :* **:**::* *::.*: **:*******:*** * .*:.: :** *:*** ** **", "identical_positions": 225, "similar_positions": 200, "identity": "21.13%" }, { "cls_id": "homologset.agr.FB:FBgn0003559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M4W7-1", "uniprot_id": "F1M4W7_RAT", "id": "F1M4W7-1", "name": "Cleavage stimulation factor subunit 3", "aln": "----------MSGDAAAEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQP-IDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLH---IDLWKCYLSYVRETKGKLPSYKEK---MAQAYDFALDKIG-MEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPS---------VP-PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSK--------LLAEKG--------------------------------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYN-RLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTR-HHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFR--EEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVR--IITGGAPELAVEGNGPVESS----------AVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LI7-1", "uniprot_id": "CSTF3_MOUSE", "id": "Q99LI7-1", "name": "Cleavage stimulation factor subunit 3", "aln": "----------MSGDAAAEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQP-IDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLH---IDLWKCYLSYVRETKGKLPSYKEK---MAQAYDFALDKIG-MEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPS---------VP-PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSK--------LLAEKG--------------------------------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYN-RLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDARTR-HHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFR--EEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVR--IITGGAPELAVEGNGPVESS----------AVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12996-1", "uniprot_id": "CSTF3_HUMAN", "id": "Q12996-1", "name": "Cleavage stimulation factor subunit 3", "aln": "----------MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQP-IDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLH---IDLWKCYLSYVRETKGKLPSYKEK---MAQAYDFALDKIG-MEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPS---------VP-PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSK--------LLAEKG--------------------------------DMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYN-RLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTR-HHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFK--EEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVR--IITGGAPELAVEGNGPVESN----------AVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25991-1", "uniprot_id": "SUF_DROME", "id": "P25991-1", "name": "Protein suppressor of forked", "aln": "---------MSSARDLIKVDIEWGMERLVRAQQVVELRPYDIESWSVMIREAQTRP-IHEVRSLYESLVNVFPTTARYWKLYIEMEMRSRYYERVEKLFQRCLVKILN---IDLWKLYLTYVKETKSGLSTHKEK---MAQAYDFALEKIG-MDLHSFSIWQDYIYFLRGVEAVGNYAENQKITAVRRVYQKAVVTPIVGIEQLWKDYIAFEQNINPIISEKMSLERSKDYMNARRVAKELEYHTKGLNRNLPA---------VP-PTLTKEEVKQVELWKRFITYEKSNPLRTEDTALVTRRVMFATEQCLLVLTHHPAVWHQASQFLDTSAR--------VLTEKGVRTSVENISPILCVPVVNQIEWVMAFAWWWAKDVQAAKIFADECANILERSINGVLNRNALLYFAYADFEEGRLKYEKVHTMYN-KLLQLPDIDPTLVYVQYMKFARRAEGIKSARSIFKKAREDVRSR-YHIFVAAALMEYYCSKDKEIAFRIFELGLKRFGGSPEYVMCYIDYLSHLNEDNNTRVLFERVLSSGGLSPHKSVEVWNRFLEFESNIGDLSSIVKVERRRSAVFENLKEYEGKETAQLVDRYKFLDLYPCTSTELKSIGYAENVGIILNKVGGG--AQSQNTGEVETDSEATPPLPRPDFSQMIPFKPRPCAHPGAHPLAGGVFPQPPALAALCATLPPPNSFRGPFVSVELLFDIFMRLNLPDSAPQPNGDNELSPKIFDLAKSVHWIVDTSTYTGVQHSVTAVPPRRRRLLPGGDDSDDELQTAVPPSHDIYRLRQLKRFAKSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25298-1", "uniprot_id": "RNA14_YEAST", "id": "P25298-1", "name": "mRNA 3'-end-processing protein RNA14", "aln": "MSSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNLITGGQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEYLNFLEQWKPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLRTANKKNIPQPGTSDSNIQQLQIWLNWIKWERENKLMLS-EDMLSQRISYVYKQGIQYMIFSAEMWYDYSMYISENSDRQNILYTALLANPD------------------------------SPSLTFKLSECYELDNDSESVSNCFDKCTQTLLSQYKKIASDVNSGEDNNTEYEQELLYKQREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTHDVYVENAYLEFQNQNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEK-VQDLTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFP-----QENLIEVFTSRYQIQNSNLIKKLELTYMYNEEED--------------SYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKKFKRDSELP--TEVLDLLSVIPKRQYFNTNLLDAQKLVNFLNDQVEIPTVESTKSG--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : .: :: .* :: :: :*: :.: :.*. ** : ** . *.* :: *: :: ***:: :** *. :.**. ** *::..:. :. :* :.:*:::.::* . :: * .:* :*: **. :....: *:*:* :*..*:: *: .:*::*. * :*: ** :.*: : * :**:** : :* :**.* * :* * : .: :*:::* .:* :*:.* * . ::::*: :. :* : : . . :*:: : ::. .: :*:: . .: . * * * . . : . * * . .. . *. :: *: .** . *:*: **: :* .*:.:.* :* *.*: * :.::* * :*: .:* . **:::***** : . *: *:*:* .**:*.: :.*** : . : *:: ::: :**::*:* .: .:*:* * : : :..**:: : . **. : : . . . . .* .::: . .. : .. :* . * :* *. ::..: *.::: :. .. ", "identical_positions": 123, "similar_positions": 245, "identity": "15.3%" }, { "cls_id": "homologset.agr.FB:FBgn0003575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G746-1", "uniprot_id": "A0A8I6G746_RAT", "id": "A0A8I6G746-1", "name": "Zinc finger CCCH domain-containing protein 4", "aln": "MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDCRAATPHLLHHRLPLPDDREDGELEEGELEDDGAEDIQDTPGGQERSR-----KEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASS-SDDFSDFSDDSDFSPSEKGHRKYRDYSPPYVPSHQQYSSSHNTPLPKKSYSKIDSKGYSMYEDYENEQYGEYEGDE-EEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMG-EHPEDEEDLYDEEIEYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGS-RGGMSKGGMNDEDDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYIHERDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMAMPAHEPLSPQQLQQ-DMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHP-------------DMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMAPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQEEE-RARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHTTGGRLADPRLSRDPRLSRHAETSGGSGPG----DSGPSDPRLARALPTSKTEGSLHSS----PACPSGSKGQ--PPAEEEEGERALREKAVTIPLDPLPGHP------------------LRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQD-VPPVPAALQSLPALDPRLHRSTPPGPPNTRQQRPGSTDPST--------------SGSNLPDFELLSRILKTVNVN----TPGQSEKPSDPRVRKTPTDPRLQKPADPGAASRAAKPCPTEASPPAASPSGDS-PPATAPYDPRVLAAGGLGQGSSSGQSSVLSG--------ISLYDPRTPNAGGKTAELTSDTSAQPKGPEGNGKSSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATTQPGVHNLPVPTLFGTVKPTPKTGT---GSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPZ3-1", "uniprot_id": "ZC3H4_MOUSE", "id": "Q6ZPZ3-1", "name": "Zinc finger CCCH domain-containing protein 4", "aln": "MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDGRAATPHLLHHRLPLPDDREDGELEEGELEDDGAEEVQDPPGGQERSR-----KEKGEKHHSDSEEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASS-SDDFSDFSDDSDFSPSEKSHRKYRDYSPPYAPSHQQYSSSHNAPLPKKSYSKMDSKGYSMYEDYENEQYGEYEGDE-EEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMG-EHPEDEEDLYEEEIEYGESEEPMGDDDYDDYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGG-RGGMSKGGMNDDEDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHG-DFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMSLPTHEPLSPQQLQQ-DMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHP-------------DMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQEEE-RARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHPTGSRLSDPRLSRDPRLSRHAETSGGSGPG----DSGPSDPRLARALPTSKAEGSLHSS----PAGPSSSKGQ--PPAEEEEGERALREKAVNIPLDPLPGHP------------------LRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQD-VPPVPAALQSLPALDPRLHRSTPPGPPNTRQ-RPGSTDPST--------------SGSNLPDFELLSRILKTVNVN----TPGQSEKPSDPRVRKTPTDPRLQKPADPVAASRAAKPCPTEASPPAASPSGDSSPPATAPYDPRVLAAGGLGQGSSSGQSSVLSG--------ISLYDPRTPNAGGKTAEPASDTSAQPKGPEGNGKGSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATPQPGVHNLPVPTLFGTVKPAPKTGT---GSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPT8-1", "uniprot_id": "ZC3H4_HUMAN", "id": "Q9UPT8-1", "name": "Zinc finger CCCH domain-containing protein 4", "aln": "MEAAPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGELEDDGAEETQDTSGGPERSR-----KEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASS-SDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPSHATPLPKKAYSKMDSKSYGMYEDYENEQYGEYEGDE-EEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDEEDFYEEEMDYGESEEPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRG-RGKGMGRGRGRGGSRGGMNKGGMNDDEDFYDEDMGDGGGGSYRSRDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHG-DFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHP-------------------------DMHADMHADMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLLGDAEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPPASVGELSSSGLGDPRLQKGHPTGSRLADPRLSRDPRLTRHVEASGGSGPG----DSGPSDPRLARALPTSKPEGSLHSS----PVGPSSSKGSGPPPTEEEEGERALREKAVNIPLDPLPGHP------------------LRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPAALQSMPTLDPRLHRAATAGPPNARQRPGASTDSST--------------QGANLPDFELLSRILKTVNATGSSAAPGSSDKPSDPRVRKAPTDPRLQKPTDSTASSRAAKPGPAEAPSPTASPSGDASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSG--------ISLYDPRTPNAGGKATEPAADTGAQPKGAEGNGKSSASKAKEPPFVRKSALEQPETGKAGADGGTPTDRYNSYNRPRPKAAAAPAATTATPPPEGAPPQPGVHNLPVPTLFGTVKQTPKTGS---GSPFAGNSPAREGEQDAASLKDVFKGFDPTASPFCQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7FCG9-1", "uniprot_id": "F7FCG9_RAT", "id": "F7FCG9-1", "name": "", "aln": "--------------------------------------------MDFENLFSKPPNPALGKKPAADP-EERIDE----------------TDGTEVEEAQTENVKR----KVKRDCEPIP------KKFKHLG--------------------------------------------HAGTPPKSLPRKKSRSKDYDP---YSD-----------GETCSQESEDNFDKELQQYIQAKEMASVAPPSLLPEESVKKAGTGDTQQTAKQ--------------------------------------------------KNKKSKAGLKKVKQKKMKRKWL-GTGNKGSNALLKIG-------------GSQGKADGPEEKQPRVRMSQGFINQHTVERKGKQVCKYFLERKCIKGDQCKFDHDAEIEKKKEMCKYYVQGYCTKGENCLYLHN-EYPCKFYHTGTKCYQG-----------------------------------------------------------------DHCNFSHAP------------LTAETQELLAK-VLDTDKKSCK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ48-1", "uniprot_id": "ZC3H8_MOUSE", "id": "Q9JJ48-1", "name": "Zinc finger CCCH domain-containing protein 8", "aln": "--------------------------------------------MDFENLFSKPPNPALGKKPAADP-EERIDE----------------IDGTEVEETQTEKVKW----KVKRDREQIP------KKFKHLG--------------------------------------------NAATSPKSLLRKKSRSKDYDP---YSD-----------GETCSQGSEDNFDKELQQYIQAKEMANAAQPSLLPEESVKKAGAEGTQQTAKQ--------------------------------------------------KNKKSKAGHKKVKQKKMKRKWP-GTGDKGSRALLKNS-------------GSREQTDEPEEKQPRVRMSQGFINQHTVERKGKQVCKYFLERKCIKGDQCKFDHDAEIEKKKEMCKYYVQGYCTKGENCLYLHS-EYPCKFYHTGTKCYQG-----------------------------------------------------------------DHCNFSHAP------------LTAETQELLAK-VLDTDKKSCK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5P1-1", "uniprot_id": "ZC3H8_HUMAN", "id": "Q8N5P1-1", "name": "Zinc finger CCCH domain-containing protein 8", "aln": "--------------------------------------------MDFENLFSKPPNPALG-KTATDS-DERIDD----------------EIDTEVEETQEE--------KIKLECEQIP------KKFRHS-----------------------------------------------AISPKSSLHRKSRSKDYDV---YSD-----------NDICSQESEDNFAKELQQYIQAREMANAAQ----PEESTKKEGVKDTPQAAKQ--------------------------------------------------KNKNLKAGHKNGKQKKMKRKWP-GPGNKGSNALLRNS-------------GSQEEDGKPKEKQQ--HLSQAFINQHTVERKGKQICKYFLERKCIKGDQCKFDHDAEIEKKKEMCKFYVQGYCTRGENCLYLHN-EYPCKFYHTGTKCYQG-----------------------------------------------------------------EYCKFSHAP------------LTPETQELLAK-VLDTEKKSCK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LTU5-1", "uniprot_id": "F1LTU5_RAT", "id": "F1LTU5-1", "name": "", "aln": "-------------------------------------------MTDSEHAGHDREDGELEDGEIDDAGFEETQD----------------HEAKENEKQKNEKAYRKSRKKHKKEREKKKSKRRKHEKHKHNSPSGD-SSDYSLDSDVEHMQSSHKKRTSFYRDYDVPFSQHRRISGSYRTSKKSQHNKKFNSKEYAESSFYSDDYFGNYSDDNFGNYSNQEGEEDFSSQLKYYRQSQERS----GSSFSKESGKKLRSRESPPGTEY--------------------------------------------------RIKNFNVSHGHLLPRKIRRKEHCGARVIKGPHVFSAV-------------DDFQEYSKPGKKWK--VMTQEFINQHTVEHKGKQICKYFLEGRCIKGDHCKFNHDAELEKKK----------------------------------------------------------EVLNADEELVNEDERELEELRKHGITPLPKPPPGVGLLPTPS----EHFPFSDPEDDFETDLSDDTKKIPSLFEIVVKPTVDLAHKIGKKPPAFYNSTSPPGPQYEESSHCPQHMYSSESSPGPGSNIPQGSESPVRHPGSPGHHPCIGPPGPPMQENPPLLPGSSEVVGPHSQAGGLVQLDT---LPSMGGAYHSPGFPGHVMKVPRESHSSTASLYQQMPSEVQLSADSECLQGSAEVYDDYYPQNAAHSFQPPDNSADEMWHEEFAQQQPPGAHDSPHLGSGPDTSSTLTSHCPLPASG----LPPAVQRALFIPLTQRYQEDEEPAGTQP---HRASSKEEDDTVNWYSSSEEEEGSGVKSILRTLQKQTGTLRNQQHPPTELSIPTDPRLAKEKRKGNQVVDPRLRTVPRQDIRKPHESVPVDLRLVWDPRKFRGNGGAPGGSSATGAKFDLR----HTSAGANHKPKRRDDDDEDTERELREKAFLIPLDSSPGVV------------------LQDPRSQLRQFSHIKMDIILNKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLSRLWNTKSD-HQGTLSLDPTSAAK--------------ARMSLTPREGCLEQSGDLHSSGGKLGDPRLQKNFDPRLHRLPNTESPQVAIKDSHSLRNALPLARWNPALSQPSTAAPVTVAPVTLPLYASKLSS-DGLPPGTPSSVLSG--------ISLYDPRDKGSLSATELSTISSGENTE-----------NQKKSG-VKNSDKNQPSPGEVILPQKTTADMKVPVDGPADVQTDVLSSADGVQAPAVHSLPIQALTGLIGPPYSDPRQAREPGQ---ASPTPDDDPSRETDDKS--LKEVFKTFDPTASPFC-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYK8-1", "uniprot_id": "ZC3H6_MOUSE", "id": "Q8BYK8-1", "name": "Zinc finger CCCH domain-containing protein 6", "aln": "-------------------------------------------MTDSEHAGHDREDGELEDGEIDDAGFEETQD----------------QEAKENEKQKNEKAYRKSRKKHKKEREKKKSKRRKHEKHKHNSPSGDDSSDYSLDSDVERMQSSRKKRTSSYRDYDVPFSQHRRISGSYMTSKKSQHNKKTNSKEYAESSFYSDDYFGNYSDDNFGNYSNQEGEEDFSSQLKYYRQSQESS----GSSFSKESGKKLRSKGSPPGTEY--------------------------------------------------RIKSFDVSHGHLLPKKIRRKEHCGARVIKGPYVFSGM-------------DDFQEYSKPGKKWK--VMTQEFINQHTVEHKGKQICKYFLEGRCIKGDHCKFNHDAELEKKKEVCKYYLQGYCTKGENCIYMHS-EFPCKFYHSGAKCYQGDKCKFSHDDLTKETRKLLDKVLNADEELVNEDERELEELRKRGITPLPKPPPGVGLLPTPS----EHFPFSDPEDDFETDLSDDMKKIPSLFEIVVKPTVDLAHKIGKKPPAFYNSTSPPGPQFEESSHCPQRMYSSESSPGPGSKVPQGCESPVRHPGSPGHHPCVGPPGPPMQENPSLLPSSSEIVGPHSQAGGLVQLDT---LPSMGGAYHSPGFPGHSVKVPRESHSSPASLYQQMPSEMQRSADSESMQGSAEFYDDYYPQHAAHNFQPPDNSADEMWHEEFAQQQPPIARDTAHLGSGPNSSSRMTSHCPLSASG----LPPAVQRALFIPLTQRYQEDEEPAGTQP---HRASSKEEDDTANWYSSSEEEEGSGVKSILRTLQKQTGTLRNQQLPPTELSVPTDPRLAKEKRKRNQVVDPRLRTVPRQDIKKPHESVPVDLRLVWDPKKLRGNGGAPGGSSARGAEFDLR----HTNAGANHKSKRREDDDEDSERELREKAFLIPLDSSPGIV------------------LQDPRSQLRQFSHIKMDIILNKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLNRLWNTKSD-HQGALSLDPTSAAK--------------AKLSLTHREGCLEQSGDLHSSGGKLGDPRLQKNFDPRLHRLPNTESHQVTAKDSHSSRSALPLARWNPALSQPSTAAPINVASVTPPLYAPKLSS-EGLPPGTSSSVLSG--------ISLYDPRDKGSLSATELSTISSGENTE-----------SQKKSG-LKNSDKNQPSPGEVTVPQNTTADMEVPVDGPVDMQTDILRSADKVQVPAVHSLPIQALTGLLRPPYSDPRQAREPGQ---ASPTPDE----ETDDKP--LKEVFKTFDPTASPFC-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61129-1", "uniprot_id": "ZC3H6_HUMAN", "id": "P61129-1", "name": "Zinc finger CCCH domain-containing protein 6", "aln": "-------------------------------------------MTDSEHAGHDREDGELEDGEIDDAGFEEIQE----------------KEAKENEKQKSEKAYRKSRKKHKKEREKKKSKRRKREKHKHNSPSSDDSSDYSLDSDVEHTESSHKKRTGFYRDYDIPFTQRGHISGSYITSKKGQHNKKFKSKEYDEYSTYSDDNFGNYSDDNFGNYG-QETEEDFANQLKQYRQAKETSNIALGSSFSKESGKKQRMKGVQQGIEQ--------------------------------------------------RVKSFNVGRGRGLPKKIKRKER-GGRTNKGPNVFSVS-------------DDFQEYNKPGKKWK--VMTQEFINQHTVEHKGKQICKYFLEGRCIKGDQCKFDHDAELEKRKEICKFYLQGYCTKGENCIYMHN-EFPCKFYHSGAKCYQGDNCKFSHDDLTKETKKLLDKVLNTDEELINEDERELEELRKRGITPLPKPPPGVGLLPTPP----EHFPFSDPEDDFQTDFSDDFRKIPSLFEIVVKPTVDLAHKIGRKPPAFYTSASPPGPQFQGSSPHPQHIYSSGSSPGPGPNMSQGHSSPVMHPGSPGHHPCAGPPGLPVPQSPPLPPGPPEIVGPQNQAGVLVQPDTSLTPPSMGGAYHSPGFPGHVMKVPRENHCSPGSSYQQSPGEMQLNTNYESLQNPAEFYDNYYAQHSIHNFQPPNNSGDGMWHGEFAQQQPPVVQDSPNHGSGSDGSSTRTGHGPLPVPG----LLPAVQRALFVRLTQRYQEDEEQTSTQP---HRAPSKEEDDTVNWYSSSEEEEGSSVKSILKTLQKQTETLRNQQQPSTELSTPTDPRLAKEKSKGNQVVDPRLRTIPRQDIRKPSESAPLDLRLAWDPRKLRGNGSGHIGSSVGGAKFDLH----HANAGTNVKHKRGDDDDEDTERELREKAFLIPLDASPGIM------------------LQDPRSQLRQFSHIKMDITLTKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLNRLWNTKSDLHQNTVSIDPKLAAK--------------AKINTTNREGYLEQFGDSHGSGAKLGDPRLQKNFDPRLHRLPNTESHQVVMKDSHASKGAPHLPRSNPGSSQPSGAGTSNSGSGALPPYAPKLSSSAGLPLGTSTSVLSG--------ISLYDPRDHGSSSTSELATASSGENSK-----------NQKKSGGLKSSDKTEPSPGEAILPQKPSPNVGVTLEGPADPQADVPRSSGKVQVPAVHSLPVQALTGLIRPQYSDPRQARQPGQ---GSPTPDNDPGRETDDKS--LKEVFKTFDPTASPFC-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22293-1", "uniprot_id": "SUS_DROME", "id": "P22293-1", "name": "Protein suppressor of sable", "aln": "-------------------------------------MSVALADEPLIDLEEDLEDGEIDDDEEDEQQSSKIQVQKKTFVGDDDVQFVGVEAKNQNDDEDVVYVGPSTDAVCLQNSNSTKSKKPRPLEDDHASSIELAIANALKKKGIEPPMPRMRSSNQDTSDQSLEGSGEGLATANPLLQSTRSSRRRKRKKEREREQKKDKEQQNRSRRDENDVSVVPGGVEDMDEYEMMNVRGGSPPPGGAAPPLSSCGQRFSGADWDMDDGSAATG------------------------------------------------AAGLGAGGGGGYNSHSSYDSYSDEETNGPGLMNQRR------------RTRRDNEKEHQRGVNNRKRRDRDRLEGGLAGSGSKRNRRDSGEGGGGGQEKMGGSNRVEPRKLELCKFYLMDCCAKRDKCSYMHK-EFPCKYYYLGMDCYAGDDCLFYHGEPLSEQLRNVLLKHMETAPKEILGDFKRISRDIAIVQMTRRHEQLCDQLNRENTWNSIGCGLMGKRQDHQMQQQQQQLQHQQLQQQQEQQQTQQQAAADGGGCIPSLLDMVINPPLSENKRKSRWTEKMGAKAAAGAAGSSERDSTSPDAKPLPPHLDLANLSHVLSAENMAKLNKLGITNLEQMLQVPFG-----QLTEAGLTLVEIGEIQRKAEDAKPQTQAELESSTPPSKRETEANNSNSKSNGLIMVDYTQYLKDAHVSFSGNDPLDDDRDDDEQLIIDDGNDSTAEEDQQPKKAKAPPAATHESSTEEAPLPSVFDLPSFMNNMLGQGSSARQLLPASATSPNQENAHLPGGDQSTHKSAPIGGGTSTNVLGRILFGDKQSDPEARAAFYRDIIRNPFKAHSGDGDVDSSNENSNSNSHSLTPTPTPEPGSQSPKPEDHDQDMPELPVIAPALPPTTPSLYVRRSMYDFDPVKEQEHGRQELLTEEKEQYQRDTDMRLPFEPMKHYMPATEIDAAIFSHTPIRWQLHEVTIEESSYAQIRASALHKEQRELRDPRMRRILGLPETPDNSGPLGSVPIMGPSSFSVDNIARCATTIASPDLETAVRDSTPSSPPPSVVNLPSMSVPPPSMRVPPPNIQVEKPTVRTDPRRDPRRAVLQAPTKGASTANTTAPNASGGSKQISEIRSLLQVSNWYNNLGTNNKIMVNQQLALVFTELKKFHQLPNDAPKIFDVSFIVNNTTLQQIFAKLFIFVDDNGEVVQIPEEPNGNGAALGGGGDSGGGVGGGGGGGGVVLPNLSQPPPNLSQMLRLPPPNIRMLRMSGMMMQMGNVGPPFNQPPPRGGLMGMPPNGNGLNQGVGNLGGLGQLGINQGGGPVPNGNPFNPFGGNNGGGAGVMNNMNSMGNMGMGFNNFNNNGGRGGHFPGGGSGGNGNGNNRNQRGGNHRNRNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . : .. .. . : : : * : .* .. ::: . :. . . . : . . : . .*. : *:. . : :: ", "identical_positions": 4, "similar_positions": 41, "identity": "0.28%" }, { "cls_id": "homologset.agr.FB:FBgn0003607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83916-1", "uniprot_id": "CBX1_HUMAN", "id": "P83916-1", "name": "Chromobox protein homolog 1", "aln": "-----------------------------MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQS-----QKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEES------EKPR----------------GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83917-1", "uniprot_id": "CBX1_MOUSE", "id": "P83917-1", "name": "Chromobox protein homolog 1", "aln": "-----------------------------MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQS-----QKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEES------EKPR----------------GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3T3-1", "uniprot_id": "D4A3T3_RAT", "id": "D4A3T3-1", "name": "", "aln": "-----------------------------MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQS-----QKTAHETDKSDGGKRKADSDSEDKGEESKPKKKKEES------EKPR----------------GFARGLEPERIIGATDSSGELMFLMKWSSS-----------------VARSGLEL-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QM86-1", "uniprot_id": "F1QM86_DANRE", "id": "F1QM86-1", "name": "", "aln": "MSMSQPTETVSDAPSVTEEVSPDSKLAATAGKKQTKKKVEDVVEEEEEEYVVEKVLDRRVVKGRVEYLLKWKGFSEEDNTWEPEDNLDCPDLIAEYMTK-----HKIN--DDKKESSAKRKESDTDGGGEDSRPKKRKDEQ------DKPR----------------GFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEEEEKKDDKN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05205-1", "uniprot_id": "HP1_DROME", "id": "P05205-1", "name": "Heterochromatin protein 1", "aln": "-------------------------MGKKIDNPESSAKVSDA-EEEEEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEERLSWYS---DNED------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :.. **.:. *******.***::**** **:*** *****:.: :******:**** *** :: . :. *: ... : ::: .. * ..*:*.*. :*.: ** ***:.*:*:**:*..*.* **:::.. :. * ", "identical_positions": 60, "similar_positions": 55, "identity": "24.9%" }, { "cls_id": "homologset.agr.FB:FBgn0003612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70260-1", "uniprot_id": "PIAS3_RAT", "id": "O70260-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPS--PLA------SIP------PTLLTPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKP----------------------------------------------------------KKEASEVCPPPGYGLDG-----LQYSPVQEGNQSENKKRVEVIDLT----------------------------------------IESSSDEED-LPPTKKHCPVTSAAIPALPG-----------------------SKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYSPSVITS-----LDEQDTLG-----------------------------------------------------HFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPGRVSSIVAPGSS---------------------------LREGHGGPLPSGP-----SLTGCRSDVISLD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54714-1", "uniprot_id": "PIAS3_MOUSE", "id": "O54714-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPG--PLA------PIP------PTLLTPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSC---SDCDEIQFMEDGSWCPMKP----------------------------------------------------------KKEASEVCPPPGYGLDG-----LQYSAVQEGIQPESKKRVEVIDLT----------------------------------------IESSSDEED-LPPTKKHCPVTSAAIPALPG-----------------------SKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYGPSVITS-----LDEQDTLG-----------------------------------------------------HFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVAPGSS---------------------------LREGHGGPLPSGP-----SLTGCRSDVISLD------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6X2-1", "uniprot_id": "PIAS3_HUMAN", "id": "Q9Y6X2-1", "name": "E3 SUMO-protein ligase PIAS3", "aln": "--------------------------------------MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLS--------LPPGTSP-VGSPG--PLA------PIP------PTLLAPGTLLGPKREVDMH--PPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFE-EAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSC---SDCDEIQFMEDGSWCPMKP----------------------------------------------------------KKEASEVCPPPGYGLDG-----LQYSPVQGGDPSENKKKVEVIDLT----------------------------------------IESSSDEED-LPPTKKHCSVTSAAIPALPG-----------------------SKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLG------ADIQGLDLFSFLQTESQHYGPSVITS-----LDEQDALG-----------------------------------------------------HFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPGRVSSIVAPGGA---------------------------LREGHGGPLPSGP-----SLTGCRSDIISLD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88907-1", "uniprot_id": "PIAS1_MOUSE", "id": "O88907-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPN--------VHSSPMPPTLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRS----------------------------------------------------------KKEVQEVTASYN-GVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLT----------------------------------------IDSSSDEEEEEPPAKRTCPSLSPTSPLS-------------------------NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSS---------------------------------------------------RFFPYT-SSQMFLDQLS-AGGSTSLPATNGSSSGSNSSLVSS-NS---------------------------LRESHGHGVASRSSADTASIFGIIPDIISLD------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIY4-1", "uniprot_id": "A0A8I6AIY4_RAT", "id": "A0A8I6AIY4-1", "name": "", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPN--------VHSSPMPATLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGSWAPMRS----------------------------------------------------------KKEVQEVTASYN-GVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLT----------------------------------------IDSSSDEEEEEPPAKRTCPSLSPTSPLS-------------------------NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSS---------------------------------------------------RFFPYT-SSQMFLDQLS-AGGSTSLPATNGSSSGSNSSLVSS-NS---------------------------LRESHGHGVASRSSADTASIFGIIPDIISLD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75925-1", "uniprot_id": "PIAS1_HUMAN", "id": "O75925-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "--------------------------------------MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPN--------VHSSPMPATLSPS--TIP------QLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFR-ETCFAFALTPQQVQQISSSMDIS-GTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC---TDCDEIQFKEDGTWAPMRS----------------------------------------------------------KKEVQEVSASYN-GVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLT----------------------------------------IDSSSDEEEEEPSAKRTCPSLSPTSPLN-------------------------NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPM---PYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSS---------------------------------------------------RFFPYT-SSQMFLDQLS-AGGSTSLPTTNGSSSGSNSSLVSS-NS---------------------------LRESHSHTVTNRSSTDTASIFGIIPDIISLD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C5D8-1", "uniprot_id": "PIAS2_MOUSE", "id": "Q8C5D8-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLCDLSTIKSSVFS---LDGSSSP-VEPDL--PVAGIHSLPSTSITPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRP----------------------------------------------------------KKEAMKVTSQPCTKVES--SSVFSKPCSVTVASDASKKKIDVIDLT----------------------------------------IESSSDEEED-PPAKRKCIFMSETQSSP-------------------------TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPVSSMSSDLPGLDFLSLIPVDP---------------------------------------------------------------------------------QYCPPMFLDSLTSPLTASSTSVTTTSP-HESSTHVSSSSS---------------------------RSE--TGVITSSG--------RNIPDIISLD------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75928-1", "uniprot_id": "PIAS2_HUMAN", "id": "O75928-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFS---LDGGSSP-VEPDL--AVAGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRP----------------------------------------------------------KKEAMKVSSQPCTKIES--SSVLSKPCSVTVASEASKKKVDVIDLT----------------------------------------IESSSDEEED-PPAKRKCIFMSETQSSP-------------------------TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDP---------------------------------------------------------------------------------QYCPPMFLDSLTSPLTASSTSVTTTSS-HESSTHVSSSSS---------------------------RSE--TGVITSSG--------SNIPDIISLD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AZ28-1", "uniprot_id": "PIAS2_RAT", "id": "Q6AZ28-1", "name": "E3 SUMO-protein ligase PIAS2", "aln": "--------------------------------------MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCTPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFS---LDGSSSP-VEPDL--AVAGIHSLPSTSIAPHSPSSPVASVLLQDTKPTFEMQQPSPPIPPVHPDVQLKTLPFYDVLDVLIKPTSLVQSSIQRFQ-EKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC---SDVDEIKFQEDGSWCPMRP----------------------------------------------------------KKEAMKVTSQPCTKVES--SSVFSKPCSVTVASDASKKKIDVIDLT----------------------------------------IESSSDEEED-PPAKRKCIFMSETQSSP-------------------------TKGVLMY--QPS-SVRVPSVTSVDPAAIPPS-LTDYSVPFHHTPVSSMSSDLPGEQRRNDINNEV---------------------------------------------------------------------------------QLG-------------TSSDTVQQ--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BCP8-1", "uniprot_id": "A0A8M2BCP8_DANRE", "id": "A0A8M2BCP8-1", "name": "", "aln": "--------------------------------------MADIEELRNMVSSFRVSELQVLLGFAGRNKSGRKHELLLRALHLLRSGCSSAVQIKIKELYRRRYPRTFEGLQDLAALKSSIKSFIHLDSGATA-VSSDL--TLP-----TDHSDVLQQRRESCDSPVFHESKPMMNMQQPTTLMAPVHPDVQMKSLPFYDVLDVLIKPSSLGAHAVQRFHNEKYFIFALTPQQVREVCISRDFLPGGRRDYMVQIQLRFCLAETSCPQEDNYPNGLCIKVNGKLFPLPGFAPPPKNGVEQKRPGRPLNITSLVRLSSAVPNQIVVTWAPEIGKTYSMSVYLVRQLTSPLLLQRLRMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTVPCRAVTCSHLQCFDAALYLQMNEKKPTWICPVCDKKATYESLIIDGLFMEILNDC---TDVDEIQFQEDGTWCPMRP----------------------------------------------------------KKETLKLSSPCISKIDC--SVPVRQSAVVSVPETSSTKKADVIDLT----------------------------------------LESSSDDEEDDPPLKKRCIYMSKAEEMH-------------------------SKGVLTY--QPS-TVRVPNVQSLDTSYLTSS-IADYSVPFHHSSLSTIPTDMQSLDLFSLIQGDPQQ-------------------------------------------------------------------------------HFRGPIFLDSLSSSLQSATTSASLVSSSAQYETATHSSSS---------------------------SHE--TGVITGGS--------SGLSDIISLD------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JM05-1", "uniprot_id": "PIAS4_MOUSE", "id": "Q9JM05-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKSAEPGPQAPRP--------LDP--LALHS-----------------MPRTPLSGPTVDYPVLYGKYLNGLGR--LPTKTLKPEVRLVKLPFFNMLDELLKPTELVPQSAEKLQ-ESPCIFALTPRQVEMIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EGADEIEFLAEGSWRPIRA----------------------------------------------------------EKEP------------------------------SCSPQGPILVLG----------------------------------------TSDAN--------------GLAPASSTPGI-----------------------GSGLSGPGSAGSGAGAAGSLE----------------------------NGKTGADVVDLTLDSS----------------------------------------------------------------------------------------------SSSEDEDEDEDDDEDEDE--GPRPKR----------------------------RCPFQKGLVPAC-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFF9-1", "uniprot_id": "B5DFF9_RAT", "id": "B5DFF9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKSAEPGPQAPRP--------LDP--LALHS-----------------MPRTPLSGPTVDYPVLYGKYLNGLGR--LPTKALKPEVRLVKLPFFNMLDELLKPTELVPQSAEKLQ-ESPCIFALTPRQVEMIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSDLLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAAYDQLIIDGLLSKILSEC---EDADEIEFLAEGSWRPIRA----------------------------------------------------------EKEP------------------------------SCSPQGPILVLG----------------------------------------TSDAN--------------GLAPASSTPGM-----------------------GSGLSGPGGAGGGAGAAGGLE----------------------------NGKTGADVVDLTLDSS----------------------------------------------------------------------------------------------SSSEDEDEDEDDDEDDDE--GPRPKR----------------------------RCPFQKGLVPAC-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N2W9-1", "uniprot_id": "PIAS4_HUMAN", "id": "Q8N2W9-1", "name": "E3 SUMO-protein ligase PIAS4", "aln": "-------------------------------------MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKNSEPAPQPHRP--------LDP--LTMHSTYDRAG----------AVPRTPLAGPNIDYPVLYGKYLNGLGR--LPAKTLKPEVRLVKLPFFNMLDELLKPTELVPQNNEKLQ-ESPCIFALTPRQVELIRNSRELQPGVKA---VQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSAT-NRITVTWG-NYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAPYDQLIIDGLLSKILSEC---EDADEIEYLVDGSWCPIRA----------------------------------------------------------EKER------------------------------SCSPQGAILVLG----------------------------------------PSDAN--------------GLLPAPSVN-------------------------GSGALG---STGGGGPVGSME----------------------------NGKPGADVVDLTLDSS----------------------------------------------------------------------------------------------SSSEDEEEEEEEEEDEDEE-GPRPKR----------------------------RCPFQKGLVPAC-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4C4-1", "uniprot_id": "PIS4A_DANRE", "id": "F1R4C4-1", "name": "E3 SUMO-protein ligase PIAS4-A", "aln": "-------------------------------------MAAELVEAMNMVKSFRVSDLQTLLASMGRSKSGLKQDLVGRALRLVQTEYSPELLKNVRQLYETRFPKASAWLAARRPET--------VAVNYPALNS-----------------SPRGTGQG---------TDYLNGIP---KPAPPPAAEVKLVPLPFYHNLETLLPPTELVAQNSEKLQ-ESQCVFDLTPNQVDQIRNSSELRPGMKS---VQVVLRICYTDSIGVQEDQYPPNIAVKVNQSYCHVPGYYPSNKPGVEPRRPCRPVNITPWLHLSTVT-NRVTITWG-NFGKRYSVAVYLVRVFTSGELFNQLKHCSVENPDRCRERIQDKLRFDPESEIATTGLRVSLICPLVKMRLGVPCRVLTCAHLQCFDAVFFLQMNEKKPTWTCPVCDKPAPFELLTIDGLLSEILKETP--EDVEEIEYLTDGSWRPIRD----------------------------------------------------------DKEKERE------------------------RENSRTPDYPVVDIC----------------------------------------VPEAN--------------GHSPAHSGTN------------------------QTGKSG---SGGASAGTGSTS----------------------------GGSGGGTVVDLTLDDS----------------------------------------------------------------------------------------------SEEEGGGGAEDSEETDDSQDSPAPKRG---------------------------RYDYDKDLVTAY-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7P5-1", "uniprot_id": "A1Z7P5_DROME", "id": "A1Z7P5-1", "name": "", "aln": "MRKTRSQTARTQAENAATSSSPGHQSTSSAPIAVNPFDSTKYKECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTN-LELLAPKVQEVYAQSVQEQNATLQYIDPTR------MYSHIQLPPTVQPNP----------VGLVGSGQGVQVPGGQMNVVGGAPFLHTHS-INSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQ-EVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGL----------------------------------------------------------RSETQILDTP-----------------------SKPAQKVEVISDD----------------------------------------IELISDDAKPVKRDLSPAQDEQPTSTSNSE-----------------------TVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQ---------------------------------------------------------------------------------------TVSEQQLQQQQHEQPATAAVHASLLESLAAAVAD---------------------------QKHFQLLDLAAVAAAAAATASSGQSQNAGP-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12216-1", "uniprot_id": "SIZ2_YEAST", "id": "Q12216-1", "name": "E3 SUMO-protein ligase SIZ2", "aln": "------MASVMSNNNNNNNNNNASYMFTNPLSNTGGGLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDPWRPKAIKILIAKVRINSSLPKYSTLWETLKTG------------------------AFKHPVASGQLPVTALQSTALPPYSQQQALAYS---------FTSPFYKPIVQIPDANKKLKQSAGRGCTKMKFKVSKSNHDLLKS-NKSYKLYLFSG------FSIPFIYETVGHEAIDFPYPCELVFNGTKLEDN-----VKGLKKQNGTGNPANLTPYLKVPTEM-NHLDLHYL-NIDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNCN--EDVEQVEISVDGSWKPIHN--------------------------------------------------SSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEAFIPASKS-FPTHVNPR----------NDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNY----------------------QDAFQMRSFLNQGATTNINDTPTNNSS--INSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQ--------RNPYGPNYNTTAQDRNLLG---------------------------------------------------IEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSG--------HGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFN---TSAQDNSEVVDLTSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04195-1", "uniprot_id": "SIZ1_YEAST", "id": "Q04195-1", "name": "E3 SUMO-protein ligase SIZ1", "aln": "----------MINLEDYWEDETP-----GPDREPTNELRNEVEETITLMELLKVSELKDICRSVSFPVSGRKAVLQDLIRNFLQNALVVGKSDPYRVQAVKFLIERIRKNEPLPVYKDLWNALRKGTPLSAITVRSMEGPPTVQQQSPSVIRQSPTQRRKTSTTSSTSRAPPPTNPDASSSSSSFAVPTIHFKESPFYKIQRLIPELVMNVEVTGGRGMCSAKFKLSKADYNLLSNPNSKHRLYLFSG------MINPLGSR--GNEPIQFPFPNELRCNNVQIKDN-----IRGFKSKPGTAKPADLTPHLKPYTQQ-NNVELIYA-FTTKEYKLFGYIVEMITPEQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQNCQ--KNVEQVELTSDGKWTAILEDDDDSDSDSNDGSRSPEKGTSVSDHHCSSSHPSEPIIINLDSDDDEPNGNNPHVTNNHDDSNRHSNDNNNNSIKNNDSHNKNNNNNNNNNNNNNDNNNSIENNDSNSNNKHDHGSRSNTPSHNHTKNLMNDNDDDDDDRLMAEITSNHLKSTNTDILTEKGSSAPSRTLDPKSYNIVASETTTPVTNRVIPEYLGNSSSYIGKQLPNILGKTPLNVTAVDNSSHLISPDVSVSSPTPRNTASNASSSALSTPPLIRMSSLDPRGSTVPDKTIRPPINSNSYTASISDSFVQPQESSVFPPREQNMDMSFPSTVNSRFNDPRLNTTRFPDSTLRGATILSNNGLDQRNNSLPTTEAITRNDVGRQNSTPVLPTLPQNVPIRTNSNKSGLPLINNENSVPNPPNTATIPLQKSRLIVNPFIPRRPYSNVLPQKRQLSNTSSTSPIMGTWKTQDYGKKYNSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ::* :*: : . * * * ::: : .*:. : : . . : : . : :* : * : . . .* ::* . * : : : : * : ::*. ::. *: :: : :: .* : : : ** :** **: :: *.: * *:*.*** ::: : : *** **:*: : * :. . .:: . ::: :*.* . .. : : ", "identical_positions": 37, "similar_positions": 87, "identity": "3.95%" }, { "cls_id": "homologset.agr.FB:FBgn0003638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTQ1-1", "uniprot_id": "SFSWA_RAT", "id": "D3ZTQ1-1", "name": "Splicing factor, suppressor of white-apricot homolog", "aln": "------MYGAGGGRAKAERKGGVKEEAGPGGTGTGGNR-------------------VELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSAYDAEYATWN-RDYQLSEEEARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDPSEPTEEEEPSKQREKSEAENLEENEEPFIAP--LGLSVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKSEEKKKSGPTSDNEEEDDEEDGSYLHPS---LFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPPTADGTPAQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAESSSGVTSTTTTTSALAPVA-IIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGGSTQAASTAEEAPTETAVEESSEAGEDGAPEGMAETGGRGS--GKKEAGSSKSTVDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSEEDEESRECQESTSSVANPSPAAAPPSAVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN--PLPDAEVGKLEESTFGVEETGVMPCPLLVGG---RTLPMLEGKPPERPSSRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREDRSVPTAYRMSGSPGVSRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQR---PSAHSAHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3USH5-1", "uniprot_id": "SFSWA_MOUSE", "id": "Q3USH5-1", "name": "Splicing factor, suppressor of white-apricot homolog", "aln": "------MYGAGGGRAKPERKGGVKEEAGPGGTGTGGNR-------------------VELLVFGYACKLFRDDERALAQEQGQHLIPWMGDPKILIDRYDGRGHLHDLSAYDAEYATWN-RDYQLSEEEARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFIAP--LGLSVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKNEEKKKSGPTSDNEEEDDEEDGSYLHPS---LFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPPTADGTPAQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAEPSSGVTSTTTTTSALAPVA-IIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGGSTQAASTAEEAPTETAVEESGEAGEDGAPEGMAETGGRGS--GKKEAGSSKSTVDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSEEDEESRECQESTSSVANPSPAAAPPSVAVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN--PLPEAEVGKLEESTFGVEDTGVMPCPLLVGG---RTLPILEGKPPERPSNRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRMSGSPGVSRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQR---PSAHSAHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12872-1", "uniprot_id": "SFSWA_HUMAN", "id": "Q12872-1", "name": "Splicing factor, suppressor of white-apricot homolog", "aln": "------MYGASGGRAKPERKSGAKEEAGPGGAGGGGSR-------------------VELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWN-RDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFVAP--LGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPS---LFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKN--PLPEAEAGKIEESPFSVEESSTTPCPLLTGG---RPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12297-2", "uniprot_id": "SUWA_DROME", "id": "P12297-2", "name": "Protein suppressor of white apricot", "aln": "MLPYNVRNAGGGSVGGILRRTGQGSGTGSTILGNGNSPGALGAGKVSSSLENHRQPPLELLVFGYACKIFRDDEKAREMDHGKQLIPWMGDVNLKIDRYDVRGALCELAPHEAPPGGYGNRLEYLSAEEQRAEQLCEEERYLFLYNNEEELRLRQEEDLKRLQQETSG-GCFSQVGFQYD----GQSAASTSIGGSSTATSQLSPNSEESELPFVLPYTLMMAPPLDMQLPETMKQHAIIEKTARFIATQGAQMEILIKAKQANNTQFDFLTQGGHLQPYYRHLLAAIKAAKFPPAPQTPLDQQNTDKEAPSADDHSEEVAGGRRNPNQVVITVPTIKYKPSANCAYTQLISKIKGVPLQAVLQEDESSNPGNSQHSGGTASPALSCRSEGHNSQGGEFTPVLLQYNGSTFTHEEESSNREQQDDNDVNGGEPPQVELLKNTSALALAQN--YSSESEEEEDQVQPEKEEEKKPEPVLTFPVPKDSLRHIIDKTATYVIKNGRQFEETLRTKSVDRFSFLLPANEYYPYYLYKVTGDVD---------AASKEEKTRKAAAVAAALMSKKGLSFGGAAAAVSGSNLDKAPVSFSIRARDDQCPLQHTLPQEASDEETSSNAAGVEHVRPGMPDSVQRAIKQVETQLLARTAGQKGNITASPSCSSPQK---------EQRQAEERVKDKLAQIAREKLNGMIS--REKQLQLERKRKALAFLNQIKGEGAIVGSAVPVVGPNPPESAAGAATADSGDESGDSVRSIPITYFGPDDDDEVGEQRPEMRLIGSTQKDEEDDDEEDGGDLEKYNLLNDDSTNTFTSKPVLPPTAAPPPAAVLLSDDDDVQLVATTSTRSSSSRHLKTHRRSRSRSKNVRSSDS-SPSSRESSRRRRQKSSRLSREPSSNPPRKSQHS-STQRKKTPKKRRRSKSRSRSKSIRRSRSISILRNNRRSRSRSPSCRNAEQRRQQDRRRTPTKKSHKRHKRRRRSSSP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ...*. . *: * . :*. * *.. :**********:*****:* ::*::******* :: ***** ** * :*: ::* . :. * ** ** * * **:***** *:.: * . ****: ***.: : * :. *** *. . * .: . *. .. : * **.* **: * * :: * *::** * * *****:** *:. ****:**::*****.*:***** . :*:***:.: *:* .::. .:. ::::.. :.. ::..:* *. :*. : ... : . :::. : :. . : :** * .* ...*: : . . . :: :* . :: . : .. * .. :..* . . . . .. : * .. . . . . ** : * .:: :*** * ** :** :** ::*:*. :**.** * ::* .** :* :: .:: ** . .:* .. .:.* . . * .. .. .* .. * . *.: * . : : ...: :*: * : *. : :. * * : :..: . .*.*. :* * :**:::::*:** ***** . :***** ****** **: :*. .: : . : .. .. . . .* *.:* * : . : * . ..:*.:... .. . **: .. :.:.:. *:* . . . : . :.. * .. .::* * * . . : : * ** .::..** *.::. :*. * .*.::: ::.:. * .**..* .***.:* :: : * : .* :. : : *: *:: :. ", "identical_positions": 228, "similar_positions": 320, "identity": "22.98%" }, { "cls_id": "homologset.agr.FB:FBgn0003651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10589-1", "uniprot_id": "COT1_HUMAN", "id": "P10589-1", "name": "COUP transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQA--GSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQS-----QQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQPNPGQYAL------------TNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQP-----NNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDAA-----------HIESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPSRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60632-1", "uniprot_id": "COT1_MOUSE", "id": "Q60632-1", "name": "COUP transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQ-A--GSGAPHTPQTPGQPGAPATPGTQGDKGQGPPGSGQS-----QQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQPNPGQYAL------------TNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQP-----NNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDAA-----------HIESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPSRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06725-1", "uniprot_id": "N2F1A_DANRE", "id": "Q06725-1", "name": "Nuclear receptor subfamily 2 group F member 1-A", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSVWRDPQEDVAGGPPSGPNPAAQPAR-------EQQQ-A--ASAAPHTPQTPSQPGPPSTPGTAGDKG--SQNSGQS-----QQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQPNPGQYAL------------TNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQP-----NNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCIKAIVLFTS-------------------DACGLSDAA-----------HIESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPSRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24468-1", "uniprot_id": "COT2_HUMAN", "id": "P24468-1", "name": "COUP transcription factor 2", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSTWRDPQDEVPGSQGSQASQAP---PVPGPPPG-----------APHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQPTHGQFAL------------TNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQP-----NNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPTRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43135-1", "uniprot_id": "COT2_MOUSE", "id": "P43135-1", "name": "COUP transcription factor 2", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSTWRDPQDEVPGSQGSQASQAP---PVPGPPPG-----------APHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQPTHGQFAL------------TNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQP-----NNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPTRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O09018-1", "uniprot_id": "COT2_RAT", "id": "O09018-1", "name": "COUP transcription factor 2", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSTWRDPQDEVPGSQGSQASQAP---PVPGPPPG-----------APHTPQTPGQGGPASTPAQTAAGSQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPTQPTHGQFAL------------TNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQP-----NNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPTRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32T5U5-1", "uniprot_id": "A0AB32T5U5_DANRE", "id": "A0AB32T5U5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MAMVV--WRGSQDDVAETHGTLSSQTQGGLSLPTPQPGQLGLTA--SQVAPPTPQTPVQG-PPNNNNNTQSTPTNQTTQSQSEKQQPQ-HIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREVSLFTAAVQRGRMPPTQPHHGQFAL------------TNGDPLHCHSYLSGYISLLLRAEPYPTSRYGSQCMQP-----NNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS-------------------DACGLSDVA-----------HVESLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPTRFGKLLLRLPSLRTVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PH18-1", "uniprot_id": "N2F1B_DANRE", "id": "Q6PH18-1", "name": "Nuclear receptor subfamily 2 group F member 1-B", "aln": "------------------------------------------------------------------------------------------------------------MAMVVSAWRDPQEELAAVDD----------------------------------QSAAGREHLQHRHSPKSAEEKAQIAAQN-----QQHVECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPVDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMPPNQPNPSHYAL------------TNGDHLNGQCYLSGYISLLLRAEPYPASRYGNQCMQS-----GNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQSSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRFFQEQVEKLKALQVDSAEYSCAKAIVLFTS-------------------DACGLSDIP-----------HIEGLQEKSQ-----------------------CALEEYVRSQYPN----------------------QPTRFGKLLLRLPALRMVSSS------------------------------------------------------------VIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMPIQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06726-1", "uniprot_id": "NR2F5_DANRE", "id": "Q06726-1", "name": "Nuclear receptor subfamily 2 group F member 5", "aln": "------------------------------------------------------------------------------------------------------------MAMVVNQWQENISADPGSQLQMCSQEP--------------------------------GGTPGTPSGSTPGNDALSGDKIP-------NVDCMVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRGNRDCPIDQHHRNQCQYCRLKKCLKVGMRREA------VQRGRMSNSQSSPGQYLS------------NGSDPYNGQPYLSGFISLLLRAEPYPTSRYGAQCMQS-----NNLMGIENICELAARLLFSAVEWAKNIPFFPDLQLMDQVALLRMSWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAERVVAFMDHIRVFQEQVEKLKALQVDTAEYSCLKSIVLFTS-------------------DAMGLSDVA-----------HVESIQEKSQ-----------------------CALEEYVRNQYPN----------------------QPNRFGRLLLRLPSLRIVSSP------------------------------------------------------------VIEQLFFVRLVGKTPIETLLRDMLLSGSSYNWPYMPVQRDRPISIHYNENGP------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10588-1", "uniprot_id": "NR2F6_HUMAN", "id": "P10588-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------------------------------------------------------MAMVTGGWGGPGGDTNGVDKAGG---------------------------------YPRAAEDDSASPPGAASDAEPGDEERP----GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEA------VQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQP-VSELIAQLLRAEPYPAAAGRFGAGGGAA---GAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTP-------------------DACGLSDPA-----------HVESLQEKAQ-----------------------VALTEYVRAQYPS----------------------QPQRFGRLLLRLPALRAVPAS------------------------------------------------------------LISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43136-1", "uniprot_id": "NR2F6_MOUSE", "id": "P43136-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------------------------------------------------------MAMVTGGWGDPGGDTNGVDKAGGS--------------------------------YPRATEDDSASPPGATSDAEPGDEERP----GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEA------VQRGRIPHALPGPAACS---PPG------ATGVEPFTGPP-VSELIAQLLRAEPYPAAG-RFGGGG-------AVLGIDNVCELAARLLFSTVEWARHAPFFPELPAADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDAAEYGCLKAIALFTP-------------------DACGLSDPA-----------HVESLQEKAQ-----------------------VALTEYVRAQYPS----------------------QPQRFGRLLLRLPALRAVPAS------------------------------------------------------------LISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSG---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q751-1", "uniprot_id": "A0A8M9Q751_DANRE", "id": "A0A8M9Q751-1", "name": "Nuclear receptor subfamily 2 group F member 6", "aln": "------------------------------------------------------------------------------------------------------------MAMVSGGWANPNGSANGLGEKG----------------------------------YLRG-EEEGSSPQAGNSDVEGGEEDK-----ACVVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLNYTCRSNRECQIDQHHRNQCQYCRLKKCFRVGMRKEGQQ-TPTVQRGRIPPSHAGISPASMVGAGGDVGGGPGMGADFFNGQP-VSELISQLLRAEPYPNSRYGAQCGQQLQGANSSMMGIDNICELAARLLFSTIEWARNIPYFPDLPVSEQVALLRLSWSELFILNAAQSALPLHTAPLLAAAGFHSSPMPADRVVSFMDQVRVFQDQVDKLTRLQVDSVEYSCLKAIALFSP-------------------DACGLSDPA-----------HVESLQEKAQ-----------------------VALTEYERMQYPG----------------------QPQRFGRLLLRLPALRAVPAN------------------------------------------------------------LISQLFFMRLVGKTPIETLIRDMQLSGSSISWPYVPGQ--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16376-1", "uniprot_id": "7UP2_DROME", "id": "P16376-1", "name": "Steroid receptor seven-up, isoform A", "aln": "MCASPSTAPGFFNPRPQSGAELSAFDIGLSRSMGLGVPPHSAWHEPPASLGGHLHAASAGPGTTTGSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGSDMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQ-IDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREA------VQRGRVPPTQPGLAGMHG---QYQIANGDPMGIAGFNGHSYLSSYISLLLRAEPYPTSRYG-QCMQP-----NNIMGIDNICELAARLLFSAVEWAKNIPFFPELQVTDQVALLRLVWSELFVLNASQCSMPLHVAPLLAAAGLHASPMAADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTTGKLLDILYKDVPALLTKVSALLGKGSTASNDDVLAVVRDHLDELNRQEQESQAQQQAPLHLAAFMNCVAGVEAAVQQAEQAQVPTSSASASVSAPLVPSAGSAFSSCQAKSAGSEMDLLASLYAQAQATPPSSGGGDASGHNNSSGLGASLPTQSQSGSSSRNLTASPLSTSLATAPAPASASAPAPVPTSSVAQVPVPAPVPVTSSASSSSLGGGAYQTPSAAAAAAAMFHYQTPPRAAFGSAFDMFHHSTPFGVGVGHAHALAHSSGSGSASFGSPSYRYSPYSLAGSRWQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*:************ *************:****.*:**..*:* :****************:::***:* *****:. . . :* *: ******** : ::**:*:******:***::***:: *:**:* :**:***: *****:***:*.::***.********:*::**.*:*.*:***::* **:**:** *:**:.**.* *:*.**:. * .. . *:: ::.: * *: : : * * *. * : *.:* . ..: : : . .*: : . *.*.: . * . ", "identical_positions": 154, "similar_positions": 93, "identity": "20.21%" }, { "cls_id": "homologset.agr.FB:FBgn0003654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63100-1", "uniprot_id": "DC1I1_RAT", "id": "Q63100-1", "name": "Cytoplasmic dynein 1 intermediate chain 1", "aln": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQK-KEPVPDDSDLDR-KRRETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQD----------DLGPLTRTLQWDTDPSVLQLQSDSELGRRLNKLGVSKVTQVDFLPR--EVVSYSKETQTPLATHQSEEDEEDEEMVEPKVGH--------------------DSELENQDKKQETK--EAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGAYALNRVRWAQGGKEVAVGDSEGRIWIYDVG-ELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88485-1", "uniprot_id": "DC1I1_MOUSE", "id": "O88485-1", "name": "Cytoplasmic dynein 1 intermediate chain 1", "aln": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQK-KEPVQDDSDLDR-KRRETEALLQSIGISPEPP-----------------LVPTPMSPSSKSVSTPSDAGSQDS--------GDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPR--EVVSYSKETQTPLATHQSEEDEEDEEMVEPKIGH--------------------DSELENQEKKQETK--EAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVG-ELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14576-1", "uniprot_id": "DC1I1_HUMAN", "id": "O14576-1", "name": "Cytoplasmic dynein 1 intermediate chain 1", "aln": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQK-KEPVQDDSDLDR-KRRETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDS--------GDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPR--EVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQ--------------------DSELENQDKKQEVK--EAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVG-ELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4F6-1", "uniprot_id": "A0A8M2B4F6_DANRE", "id": "A0A8M2B4F6-1", "name": "", "aln": "MADRSDLKAELERKKQRLAQIREEKKRKEEERKKKESEMLQR-PENVTEDSDLDR-KRRETEALLQSIGISPEPPLVQPLQLLTWDTCYFHYLVPTPMSPSSQSVSPPSETGSQES--------IDGGTVERTLQWDTDPSALQLLADSVHGCRMQRLGASKIVQIDFMPK--ELVTYSKETQTPVASNQPEE-EDDEELSVPKSEP--------------------ASQQLEEEKTQEVE--EVHPRELTNEEKEQIVHSEDFLFFFDRSIRVVERVLAEDKDIFFDYSGRDMEDKEGDLQAGSNLSFNRHFYDEHWSKHRVVTSLDWSPQYPELLVASYNTNEDAPHEPDGVVLVWNMKFKKATPEYIFHCQSSVMSVGFAQFHPNLVIGGTYSGQIAMWDNRSHRRTPVQRTPLSATAHTHPVYCVNVVGTQNANNLITVSTDGKMCSWSLDMLSQPQESMELIYNKSKPVAVTCMAFPASDVNNYVVGSEEGTVYTASRHGSKAGIGEIFDGHQGPVTGISCHNAVGPVDFSHLFTTSSFDWTVKLWSTKHNKPLYSFEDNADYVYDVMWSPVHPALFATVDGNGRLDLWNLNNYTEVPSASVSVEGGCALNRVRWASGGREVAVGDSEGRVWIYDVGEQLAVPHTDDWSKFGRTLMEIQANRGDGEEEGALELPA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62871-1", "uniprot_id": "DC1I2_RAT", "id": "Q62871-1", "name": "Cytoplasmic dynein 1 intermediate chain 2", "aln": "MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAAVSVQEESDLEK-KRREAEALLQSMGLTTDSPIVFS-----------EHWVPPPMSPSSKSVSTPSEAGSQDS--------GDGAVGSRTLHWDTDPSALQLHSDSDLGRGPIKLGMAKITQVDFPPR--EIVTYTKETQTPVTAQPKEDEEEEDDVAAPKPPV--------------------EPEEEKILKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWSTKNNKPLYSFEDNSDYVYDVIGSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINASRADAEEEAATRIPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88487-1", "uniprot_id": "DC1I2_MOUSE", "id": "O88487-1", "name": "Cytoplasmic dynein 1 intermediate chain 2", "aln": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAAVSVQEESDLEK-KRREAEALLQSMGLTTDSPIV-----------------PPPMSPSSKSVSTPSEAGSQDS--------GDGAVGSR--------------------RGPIKLGMAKITQVDFPPR--EIVTYTKETQTPVTAQPKEDEEEEDDVATPKPPV--------------------EPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13409-1", "uniprot_id": "DC1I2_HUMAN", "id": "Q13409-1", "name": "Cytoplasmic dynein 1 intermediate chain 2", "aln": "MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEK-KRREAEALLQSMGLTPESPIVFS-----------EYWVPPPMSPSSKSVSTPSEAGSQDS--------GDGAVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPR--EIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPI--------------------EPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6H7-1", "uniprot_id": "DCI2A_DANRE", "id": "E7F6H7-1", "name": "Dynein, cytoplasmic 1, intermediate chain 2a", "aln": "MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKEAELKKD-AVPLQDDSDLEK-KRREADALLQSMGITSDVSAA-----------------PAPMSPTAKSVGSPSEAGSQDS--------GDGTTGPRTLHWDCDPSTVLLHS--ELGRGPLKLAMTKMTHVDFPPK--EVVSYTKETQTPTMTEQKDEEDEEEETPAAQPEA--------------------ETEKEKPEEKQVE---EALPHELTEEEKLQILHSEEFMDFFDHSTRIVERALSEHVDVFFDYSGRDMEEKEGEMQAGTKLSLNRKFVDDRWSKQRVVTCLDWSPQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKATPEYVFHCQSAVMSAAFAKFHPNLVVGGTYSGQIVLWDNRSNRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKMCSWSLDMLSQPQDSMELVFKQSKSVAVTSMSFPLGDVNNFVVGSEDGSVYTASRHGSRAGISEMFEGHHGPITGIHCHTAAGPVDFSHLFLTASFDWTVKLWSNKNNKPLYSFEDNSDYVYDVMWSPVHPALFACVDGLGRVDLWNLNNDTEVPTASVAVDGSPALNRLRWSQSGREIAVGDSEGQIHIYDVGEQIAVPRNDEWTRFVRTLVEINENRDDAEELAAQRLAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B334-1", "uniprot_id": "A0A8M3B334_DANRE", "id": "A0A8M3B334-1", "name": "", "aln": "MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKELDGRKEGASPPQEDSDLER-KRREAEALLQSMGITDASMVQPLR-VVTEDTCLFHYLVPPPMSPSAKSVGTPSETGSQDS--------GDGGTGPRTLHWDSDPSTLLLHSDSQLGRGPLKLGMSKVTQVDFPPK--EMVSYSKETQTPTQTHHKEDEEEEEDLAVMQPVM--------------------EPQEEKDSQKEED---EASPHELTEEEKQQILHSEEFVTFFDHSSRIMERALSEQVDVFFDYSGRDLQDKEGESQAGAKLSLNRQFADERWSKHRVVTCLDWSPQYPELLVASYCSNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSAAFAQFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSASAHTHPVYCVNVVGTQNAHNLISISTDGKMCSWSLDMLSTPQDSLELVFKQSKSVAVTSMSFPLGDVNNFVVGSEDGSVYTACRHGSKAGISEMFEGHHGPITGLDCHTAAGPVDFSHLFVTSSFDWTVKLWGTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGVGHLDLWNLNNETEVPTASVTVEGNPALNRVRWAHSGREVAVGDSEGQLHIYDVGEQISVPRQDEWTRFVRTLTEINENREDVEELAAQRLAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24246-11", "uniprot_id": "DYIN_DROME", "id": "Q24246-11", "name": "Cytoplasmic dynein 1 intermediate chain", "aln": "----MDRKAELERKKAKLAALREEKDRR---RREKEIKDMEEAAGRIGGGAGIDKDQRKDLDEMLSSLGVAPVSEVLSSLSSVNSMTSD-NSNTQTPDASLQATVNGQSGGKKQPLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLSCHSSPLSGYMEDWWRPRKAHATDYYDEYNLNPGLEWEDEFTDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQSDEV---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ******** :** :****.*: *::** . : :.::: :*:: : :*.*:*:: .* :. :*. * .* . : . : *: . . * .* : . :: :::: : . : . : .**::*:* *: **:* *. :: *::**.*:*. ::: ** * .:: .: :: :.**:** * *::***:* ::.:*** ::***:*.** .**::*:*****.:*** *:**:*** :*****:***. **:*:***::********.:**** ::***:*******:********:::******:*:*::*:***:********* **:::** .:**.:*:* *:** .::*. *:***:* **:*.*** ::*:.*::: * **:**: * . **.*** *:*:***:*** *..*********:*** ** **.****** *** *::******. ****:**: : * ****: *: .* .:.:**. *:: :***. ::: * *:*::* * **. .: * ", "identical_positions": 251, "similar_positions": 180, "identity": "36.91%" }, { "cls_id": "homologset.agr.FB:FBgn0003656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK26-1", "uniprot_id": "PLPL7_RAT", "id": "Q5BK26-1", "name": "Patatin-like phospholipase domain-containing protein 7", "aln": "-------------MQKEEDVCPEAGYCLG---------TALSSWGLHFMEEHSQSTMLMGIGIGVLLTLAFVGLAAFFVYRKVSRF----------RRAEP-IPQYRFRKRDKVMFYG-----RKIMRKVTTLPHTLVGNTAAPRQR--VRKRTKVLSLAKRILRFKKEYPTLQPK--EPPPS------------LLEADLTEFDVKNSHLPSEVLYMLKNVRVLGHFEKPLFLELCKHMVFVQLQEGEHVFQPGEPDISIYVVQDGRLEVCIQDAD------------------------------------------------------------GTEVVVKEVLPGDSVHSLLSILDVITGHTAPYKT--------------------------------------------------VSARAAVASTVLWLPAAAFQGVFEKYPETLVRVVQIIMVRLQRVTFLALHNYLGLTTELFNPESQA-------------------------------------------------------------------------------------------------------------------------------------IPLLSVASVAG-RAKRQMSYGPEEQLERSPRLSEFNSSDQRS--VAVSGPLLKRSCSVPLPPIHGEIDELRQAQGSGS-NTSAFQESQEGATSDLGMAYNRARI--LPHSEEQLGSSLASKSKKS-VVAET-SAVFHYSEKP-RDEPG-------PSGRTD-AIFRAATKDLLTLMKLDDPSLLDGR--------------------------VAFLHVPAGTIVSKQG-DQDVNILFVVSGMLHVYQQKIDSL-----------------------EDTCLFLTHPGEMVGQLAVLTGEPLMFTIRANRDCSFLSISKAHFYEIMRKRPDVVLGVAHTVVRRMSSFVRQIDFALDWMEVEAGRAIYRQGDKSDCTYIVLSGRLRSVIRK-----------DDGKKRLAGEYGRGDLVGVVEMLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKILGS---LQQ--GSGT-------------GHQLGFNTASSKWDLGNPPGNLSTVAAMPVSEDVPLTAFALELQHALSAIG-PVLLLTSDNIKQRLGSAALDSIHEYRLSSWLGQQEDIHRIVLYQADSTLTP-WTQRCIRQADCILIVGLG-DQEPALGELEQMLESTAVRAQKQLILLHKEEG-PAPSRTVEWLNMRSWCSGHLHLCCPRR---------------------------VFSKRSLPKLVEMYTRIFQRPPD-------------------RHSDFSRLARILTGNAIALVLGGGGARGCAQVGILRALAECGIPVDIIGGTSIGAFMGALFAEERSYSQIRIRAKQWAEDMTSMVKTILDLTYPITSMFSGTGFNSSISNIFKDRQIEDLWLPYFAITTDITASAMRVHTDGALWRYVRASMSLSGYMPPLCDPKDGHLLMDGGYINNLPADVARSMGAKVVIAIDVGSRDETDLTNYGDALSGWWLLWKRWNPLATKVKVLNMAEIQTRLAYVCCVRQLEMVKNSDYCEYLRPPIDSYRTLDFGKFDEICEVGYQHGPAGFDIWVRSGVLEKMLQDQ-QGTSKRMD-CGVFTCPNSSFTDLAEIVSRIEP--------------------------------AKVAAVD-----DESDYQTEYEEELPAIPKET-YADFQSTGIELDSDSECE-----------------PSMSQGPHSLTSPKQSQDSFPWLPNQDDQGPRLYRPS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AJ88-1", "uniprot_id": "PLPL7_MOUSE", "id": "A2AJ88-1", "name": "Patatin-like phospholipase domain-containing protein 7", "aln": "-------------MQNEEDACLEAGYCLG---------TTLSSWRLHFMEEQSQSTMLMGIGIGALLTLAFVGITFFFVYRRVRRL----------RRAEP-TPQYRFRKRDKVMFYG-----RKIMRKVTTLPHTLVGNTSAPRQR--VRKRTKVLSLAKRILRFKKEYPTLQPK--EPPPS------------LLEADLTEFDVKNSHLPSEVLYMLKNVRVLGHFEKPLFLELCKHMVFVQLQEGEHVFQPGEPDISIYVVQDGRLEVCIQDAD------------------------------------------------------------GTEVVVKEVLPGDSVHSLLSILDVITGHTAPYKT--------------------------------------------------VSARAAVSSTVLWLPAAAFQGVFEKYPETLVRVVQIIMVRLQRVTFLALHNYLGLTTELFNPESQA-------------------------------------------------------------------------------------------------------------------------------------IPLLSVASVAG-RAKRQMSYGPEEQLERSLRPSEFSSSDHGSSCVTVSGPLLKRSCSVPLPSNHGEVDELRQSQGSGS-NTSAFQESHEGATSDLGMAYNRARI--LPHSDEQLGNSLASKSKKS-VVAETPSAIFHYSENF-RDETG-------ACGKTD-AIFRAATKDLLTLMKLDDPSLLDGR--------------------------VAFLHVPAGTLVSKQG-DQDVNILFVVSGMLHVYQQKIDSL-----------------------EDTCLFLTHPGEMVGQLAVLTGEPLMFTIRANRDCSFLSISKAHFYEIMRKRPDVVLGVAHTVVKRMSSFVRQIDFALDWMEVEAGRAIYRQGDKSDCTYIVLSGRLRSVIRK-----------DDGKKRLAGEYGRGDLVGVVETLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKILGS---LQQ--GSAT-------------GHQLGFNTASSKWDLGNPPGNLSTVAALPASEDVPLTAFALELQHALSAIG-PVLLLTSDNIKQRLGSAALDSIHEYRLSSWLGQQEDIHRIVLYQADGTLTP-WTQRCIRQADCILIVGLG-EQEPAVGELEQMLESTAVRAQKQLILLHKEDG-PVPSRTVEWLNMRSWCSGHLHLCCPRR---------------------------VFSKRSLPKLVEMYTRVFQRPPD-------------------RHSDFSRLARMLTGNAIALVLGGGGARGCAQVGILRALAECGVPVDIIGGTSIGAFMGALFAEERSYSQTRIRAKQWAEGMTSMMKTILDLTYPITSMFSGTGFNSSISNIFKDRQIEDLWLPYFAITTDITASAMRVHTDGSLWRYVRASMSLSGYMPPLCDPKDGHLLMDGGYINNLPADVARSMGAKVVIAIDVGSRDETDLTNYGDALSGWWLLWKRWNPLATKVKVLNMAEIQTRLAYVCCVRQLEMVKNSDYCEYLRPPIDSYRTLDFGKFDEICEVGYQHGRTVFDIWVRSGVLEKMLQDQ-QGTSKRKD-CGVFTCPNSSFTDLAEIVSRIEP--------------------------------AKVAAVD-----DESDYQTEYEEELPAIPKET-YADFQSTGIELDSDSEYE-----------------PSMLQGPPSLTSPEQSQDSFPWLPNQDDQGPRLEHPS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZV29-1", "uniprot_id": "PLPL7_HUMAN", "id": "Q6ZV29-1", "name": "Patatin-like phospholipase domain-containing protein 7", "aln": "-----------------------------------------------MEEEKDDSPQLTGIAVGALLALALVGVLILFMFRRLRQF----------RQAQP-TPQYRFRKRDKVMFYG-----RKIMRKVTTLPNTLVENTALPRQR--ARKRTKVLSLAKRILRFKKEYPALQPK--EPPPS------------LLEADLTEFDVKNSHLPSEVLYMLKNVRVLGHFEKPLFLELCKHIVFVQLQEGEHVFQPREPDPSICVVQDGRLEVCIQDTD------------------------------------------------------------GTEVVVKEVLAGDSVHSLLSILDIITGHAAPYKT--------------------------------------------------VSVRAAIPSTILRLPAAAFHGVFEKYPETLVRVVQIIMVRLQRVTFLALHNYLGLTTELFNAESQA-------------------------------------------------------------------------------------------------------------------------------------IPLVSVASVAAGKAKKQVFYGEEERLKKPPRLQESCDSDHGGGRPAAAGPLLKRSHSVPAPSIRKQILEELEKPGAGDPDPSAPQGGPGSATSDLGMACDRARV--FLHSDEHPGSSVASKSRKSVMVAEIPSTVSQHSESH-TDETL-------ASRKSD-AIFRAAKKDLLTLMKLEDSSLLDGR--------------------------VALLHVPAGTVVSRQG-DQDASILFVVSGLLHVYQRKIGSQ-----------------------EDTCLFLTRPGEMVGQLAVLTGEPLIFTVKANRDCSFLSISKAHFYEIMRKQPTVVLGVAHTVVKRMSSFVRQIDFALDWVEVEAGRAIYRQGDKSDCTYIMLSGRLRSVIRK-----------DDGKKRLAGEYGRGDLVGVVETLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKILGS---LQQ--GPVT-------------GHQLGLPTEGSKWDLGNPAVNLSTVAVMPVSEEVPLTAFALELEHALSAIG-PTLLLTSDNIKRRLGSAALDSVHEYRLSSWLGQQEDTHRIVLYQADGTLTP-WTQRCVRQADCILIVGLG-DQEPTVGELERMLESTAVRAQKQLILLHREEG-PAPARTVEWLNMRSWCSGHLHLCCPRR---------------------------VFSRRSLPKLVEMYKHVFQRPPD-------------------RHSDFSRLARVLTGNAIALVLGGGGARGCAQVGVLKALAECGIPVDMVGGTSIGAFVGALYSEERNYSQMRIRAKQWAEGMTSLMKAALDLTYPITSMFSGAGFNSSIFSVFKDQQIEDLWIPYFAITTDITASAMRVHTDGSLWWYVRASMSLSGYMPPLCDPKDGHLLMDGGYINNLPADVARSMGAKVVIAIDVGSRDETDLTNYGDALSGWWLLWKRWNPLATKVKVLNMAEIQTRLAYVCCVRQLEVVKSSDYCEYLRPPIDSYSTLDFGKFNEICEVGYQHGRTVFDIWGRSGVLEKMLRDQ-QGPSKKPA-SAVLTCPNASFTDLAEIVSRIEP--------------------------------AKPAMVD-----DESDYQTEYEEELLDVPRDA-YADFQSTSAQQGSDLEDE-----------------SSLRHRHPSLAFPKLSEGSS----DQDG--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T7U6-1", "uniprot_id": "A0A8N7T7U6_DANRE", "id": "A0A8N7T7U6-1", "name": "lysophospholipase", "aln": "------------MENEEQDDTCRSLVPSG---------HEIKARVQHFIEDQLHTTMWTGVLIGAAVAVSILSIFALFFYRRHKAG----------EGQSE-GPNYRFRKRDKVLFYG-----RKIMRKVQTLSSPPTSG-PVSQKR--TRKRTKVLSIARKILRIRREPPTLQPK--EPPPS------------LLEADLTEFDMQNSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFVQLQQGEGLFRPGDTDDSIFVVQDGRLDLCIHEND------------------------------------------------------------GTDVVVKHVLPGDSVHSLLSILDVITGYPAPYKT--------------------------------------------------VSARAAIPTTVLRLPAQAFQSVFDKYPETLVRVIQIIMVRLQRVTFLALHNYLGLTTELFNPESQA-------------------------------------------------------------------------------------------------------------------------------------VPLVSVAGVVGEAGQGRGPRRHSQTNEDVSDKVPQRSSDHYSDTSHMS-----REDCGKLNCTESPTTLFRKSR-----SLSTPLENTHAGSPDHNMTFDRSSK--EAPSS--PIAIQKSNRKKSVTMHHSPSAVFHYSDTGGHSSQI-------HHSKVN-AIFQAAKRDLLKIIQLQDPNLLEDR--------------------------VTLRQVKAGSVVASEG-DQDVSVQFVISGTLHVYQRLIDRE-----------------------EQSCLFVAHPGEMVGHLAVLTGEPLIFSVRAQRDCCFLSISKTHFYEIMRAEPRMVLNVAHTVVRRVSSFVRQIDFALDWMALEAGRAVYRQGDKSDSTFIVLSGRLRSVIMK-----------DDGKKELAGEYGRGDLIGVVEALTHLNRATTVHAVRDSELAKLPEGALNSIKRKYPQVVTRLIHLLGQKILGN---MQQVNGPLS-------------VRSLGFHSPTSKWDAGNPAANLSTVTILPVSEEVPLTAFTLELQHALSAIG-PTLLLTSDIIRQHLGVAALDSVHEYRLSSWLGQQEDIHRIVLYQSDGSLTP-WTQRCIRQADCIIIVGLG-EQEPTVGELERMLESSAVRAQKQLVLLHREDG-PPPAGTVEWLNMRSWISRHLHLSCPHR---------------------------VFSRRSLPKLREMYQRVFEKPPD-------------------RHSDFSRLARILTGNAIALVLGGGGARGCSQVGIIRAMSEAGIPVDLIGGTSIGSLIGALYAEERSVSRMTVRARQWAMDFGSIFKKITDLTYPVTSMFTGASFNSSIGTLFQDKQIEDLWIPYFNITTDITASSMRVHTDGSLWRYVRASMSLSGYLPPLCDPKDGHLLMDGGYINNLPADTARSMGAKLVIAVDVGSQDETDLTNYGDSLSGWWLLWKRLNPLAEKVKVLNMAEIQTRLAYVCSVRQLELVKDSDYCEYLRPPIDRYGTLDFGKFDEIADVGFQHGKTVFDVWCRSGVRETIMKDQHQEEFHKSR-STNATCPNASFTDLAEIVSRIEP--------------------------------VKQAVVD-----EESEYQTDYDEDAVLSDFDLSNPNSEHSDAQEDEDEEEE-----------------TADTADTDDEIEIRKRRHRALNHSRHHTT-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TRM4-1", "uniprot_id": "PLPL6_MOUSE", "id": "Q3TRM4-1", "name": "Patatin-like phospholipase domain-containing protein 6", "aln": "---------MGTPSHELNTTSSGAEVIQK-------TLEEGLGRRICVAQPVPFVPQVLGVMIGAGVAVLVTAVLILLVVRRLRVQ----------KTPAPEGPRYRFRKRDKVLFYG-----RKIMRKVSQSTSSLVDTSVSTTSRPRMKKKLKMLNIAKKILRIQKETPTLQRK--EPPPS------------VLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPD------------------------------------------------------------GKECVVKEVVPGDSVNSLLSILDVITGHQHPQRT--------------------------------------------------VSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQP-------------------------------------------------------------------------------------------------------------------------------------LRLFPSPGLPTRTSPVR---GSKRVVSTSGTEDTSKETSGRPLDSIGAPLPGPAGDPVKPTSLEAPPAPLLSRCISMPVDISGLQGGPR---SDFDMAYERGRISVSLQEEASGGPQTASPR----ELREQPAGACEYSYCEDESATGGCPFGPYQGRQTS-SIFEAAKRELAKLMRIEDPSLLNSR--------------------------VLLHHAKAGTIIARQG-DQDVSLHFVLWGCLHVYQRMIDKA-----------------------EEVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSHFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQR-----------GSGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGN---LQQLQGPFP-------------GSGLSVPQHS---ELTNPASNLSTVAILPVCAEVPMMAFTLELQHALQAIG-PTLLLNSDVIRALLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDTSLTP-WTVRCLRQADCILIVGLG-DQEPTVGQLEQMLENTAVRALKQLVLLHREEG-PGPTRTVEWLNMRSWCSGHLHLRCPRR---------------------------LFSRRSPAKLHELYEKVFSRRAD-------------------RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPSIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWTRGEVIEKMLTDRRSTDLNESRRADILAFPSSGFTDLAEIVSRIEP--------------------------------PTSYVSDGCADGEESDCLTEYEEDAGPDCSRDEGGSPE--GASPSTASEVE------------------------EEKSTLRQRRFLPQETPSSVADA------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R715-1", "uniprot_id": "M0R715_RAT", "id": "M0R715-1", "name": "lysophospholipase", "aln": "---------MGTPSHELNTTSSGSEVIRK-------ALEEGLGRRICVAQPVPFVPQVLGVMIGAGVAVLVTAVLILLVVRRLRVQ----------KTPAPEGPRYRFRKRDKVLFYG-----RKIMRKVSQSTSSLVDTSVSTTSRPRMKKKLKMLNIAKKILRIQKETPTLQRK--EPPPS------------VLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPD------------------------------------------------------------GKECVVKEVVPGDSVNSLLSILDVITGHQHPQRT--------------------------------------------------VSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQP-------------------------------------------------------------------------------------------------------------------------------------LRLFPSPGLPTRTSPVR---GSKRVVSTSGTEDTPKETSGRPLDPTGAPLPGPAGDPVKPTSLEAPSAPLLSRCISMPVDISGLQGGPR---SDFDMAYERGRISVSLQEEASGGPQTASPRTPTQELREQPAGACEYSFCEDESATGGCPFGPYQGRQTS-SIFEAAKRELAKLMRIEDPSLLNSR--------------------------VLLHHAKAGTIIARQG-DQDVSLHFVLWGCLHVYQRMIDKA-----------------------EEVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQR-----------GSGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGN---LQQLQGPFPA------------GSGLSVPQHS---ELTNPASNLSTVAILPVCAEVPMMAFTLELQHALQAIG-PTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDTSLTP-WTVRCLRQADCILIVGLG-DQEPTVGQLEQMLENTAVRALKQLVLLHREEG-PGPTRTVEWLNMRSWCSGHLHLRCPRR---------------------------LFSRRSPAKLHELYEKVFSRRAD-------------------RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPSIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWTRGEVIEKMLTDRRSTDLNESRRADILAFPSSGFTDLAEIVSRIEP--------------------------------PTSYVSDGCADGEESDCLTEYEEDAGPDCSRDEGGSPE--GASPSTASEVE------------------------EEKSTLRQRRFLPQETGAQ----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IY17-4", "uniprot_id": "PLPL6_HUMAN", "id": "Q8IY17-4", "name": "Patatin-like phospholipase domain-containing protein 6", "aln": "MEAPLQTGMMGTSSHGLATNSSGAKVAERDGFQDVLAPGEGSAGRICGAQPVPFVPQVLGVMIGAGVAVVVTAVLILLVVRRLRVP----------KTPAPDGPRYRFRKRDKVLFYG-----RKIMRKVSQSTSSLVDTSVSATSRPRMRKKLKMLNIAKKILRIQKETPTLQRK--EPPPA------------VLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPD------------------------------------------------------------GKECVVKEVVPGDSVNSLLSILDVITGHQHPQRT--------------------------------------------------VSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRVTFLALHNYLGLTNELFSHEIQP-------------------------------------------------------------------------------------------------------------------------------------LRLFPSPGLPTRTSPVR---GSKRMVSTSATDE-PRETPGRPPDPTGAPLPGPTGDPVKPTSLETPSAPLLSRCVSMPGDISGLQGGPR---SDFDMAYERGRISVSLQEEASGGSLAAPARTPTQEPREQPAGACEYSYCEDESATGGCPFGPYQGRQTS-SIFEAAKQELAKLMRIEDPSLLNSR--------------------------VLLHHAKAGTIIARQG-DQDVSLHFVLWGCLHVYQRMIDKA-----------------------EDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQR-----------GSGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILGN---LQQLQGPFPA------------GSGLGVPPHS---ELTNPASNLATVAILPVCAEVPMVAFTLELQHALQAIG-PTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQEDAHRIVLYQTDASLTP-WTVRCLRQADCILIVGLG-DQEPTLGQLEQMLENTAVRALKQLVLLHREEG-AGPTRTVEWLNMRSWCSGHLHLRCPRR---------------------------LFSRRSPAKLHELYEKVFSRRAD-------------------RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPPIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWSRGNVIEKMLTDRRSTDLNESRRADVLAFPSSGFTDLAEIVSRIEP--------------------------------PTSYVSDGCADGEESDCLTEYEEDAGPDCSRDEGGSPE--GASPSTASEME------------------------EEKSILRQRRCLPQEPPGSATDA------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6R2-1", "uniprot_id": "A0A8M2B6R2_DANRE", "id": "A0A8M2B6R2-1", "name": "lysophospholipase", "aln": "----------------MGQSTSDTESAEP-------PETDRFGNIKSLVEDQLQTSMVVGIVIGAGVVIVLIAVLIFFVLRRMQLR----------KLEAQEVPKYRFRKRDKVLFYG-----RKIMRKVSQSTSSLVG--ATSSTRPRLKKKQKMLNIAKKILRFKKEVPTLQMK--EPPPS------------VLEADLTEFDVANSHLPSEVLYMLKNVRVLGHFEKPLFLELCKHMVFLQFQQGEYVFRPGQPDSSIYVVQDGKLELCLTGQD------------------------------------------------------------GKDGVVKEVYPGDSVHSLLSILDVITGHQRPYKT--------------------------------------------------VSARAAEVSTVLRLPVDAFLSIFEKYPESLVRVVQIIMVRLQRVTVLALHNYLGLTNELFSHEMQP-------------------------------------------------------------------------------------------------------------------------------------RSSPLSP-HPTRSSPVR---HSKRFGSLTVPDKHREAAVQN----------ATGGDHGK----EGGTIPTLSRTISMPVDIAGMQKSLR---SDFDMAYERGRISVSAEDGVP--AFTKEQRERKVTVDEVPSG--VYLYPEEESGMD--IFSSFQGRPNA-TVFEEAQKEILRLMKIEDPSLLNGR--------------------------VTFHHAKAGSVLARQG-DQDVSLHFVLSGCLHVYQKMIDKQ-----------------------EAVCLFVTQPGEMVGQLAVLTGEPLIFTIKAERDCTFLKISKSEFYEIMREQPSVVLSAAHTVAIRMSAFVRQMDFAIDWMAVEAGRALYRQDDQSDCTYIVLNGRLRSVIRK-----------ANGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELVKLPEGTLNNIKRRYPQVVTRLIHLLGQKILGN---LQQPRGPFS-------------SSALGLPSMASSPDVTNPASNLSTVAVLPVCDEVPINAFNLELSHALSAIG-PTLLLTSDIIRERLGASALDSIHEYRLSGWLAQQEDINRIVLYQTDSGMTP-WTQRCIRQADCILIVGLG-DQEPALGELEQMLENTAVRALKQLILLHREDG-PGPSRTVEWLNMRSWCSGHLHLKCPRR---------------------------VFSRRSPTKLREVYEKVFEKTAD-------------------RHSDFSRLARVLTGNSIALVLGGGGARGCSHVGVIKAMEDTGIPIDIVGGTSIGSFIGALYAEERSAVRVKQRAREWSKAMNSVFKTVLDLTYPITSMFSGSAFNTSISKVFEDKQIEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGNLLMDGGYINNLPADIARTLGTKTVIAIDVGSQDETDLCNYGDCLSGWWLLWKRINPWAEKVKVPDMAEIQSRLAYVSCVRQLELVKKSAYCEYIRPPIDRFKTMDFGKFDEIYDVGYQHGKLVFTEWARGDIIDNMLKDHRSADYNDSKKTDSCPCPSADFTDLAEIVSRIEP--------------------------------VQSYVG---ADAEESDYATEYEEDGMDTVREEEGEEEEEEGEDPEDQSPGEWG---------------PNGVFPPDEDKTVRQRKNVSRDPNADFSGVSDC---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U969-1", "uniprot_id": "SWS_DROME", "id": "Q9U969-1", "name": "Neuropathy target esterase sws", "aln": "-------------MDVLEMLRASASGSYN---------TIFSDAWCQYVSKQITATVYMYFALVMMSLLFIAWFLYFKRMARLRLRDEIARSISTVTNSSGDMRGLRFRKRDKMLFYG-----RRMLRKMKNVSGQMYSSGKGYKRR-------AVMRFARRILQLRRDNMPLEMRTVEPPAE------------YLEETIEG----SDRVPPDALYMLQSIRIFGHFEKPVFLRLCKHTQLLELMAGDYLFKITDPDDSVYIVQSGMINVYISNAD------------------------------------------------------------GSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYKT--------------------------------------------------VTAKAIEKSVVIRLPMQAFEEVFQDNPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRY-------------------------------------------------------------------------------------------------------------------------------------KSVSTMSGPINSQTSQSSRQAPNGPPMVISQMNLMQSAVSGTG---------SSGVSVTVTRPPSSPSRHSREEHTLSDPNPNPDGSFHGTTNLFTEVHGDAPNADLFHQQQQQHSVGNLSTRRSSITLMAPDGSHSCLQTPGVTTSID------MRLVQS-SAVDSLRKELG--LSEEDSHIIEPF--------------------------VELRELEPNVTLITEGNADDVCVWFVMTGTLAVYQSNQDATRAKQDK-----------------SDMLIHFVHPGEIVGGLAMLTGEASAYTIRSRSITRIAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITH-----------PGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTKLISFLSHRFLGS---MQTRSGSGAP------------GAPVEANPVT---------HKYSTVALVPITDEVPMTPFTYELYHSLCAIG-PVLRLTSDVVRKQLGSNIFEAANEYRLTSWLAQQEDRNIITLYQCDSSLSA-WTQRCMRQADVILIVGLG-DRSHLVGKFEREIDRLAMRTQKELVLLYPEASNAKPANTLSWLNARPWVTKHHHVLCVKR---------------------------IFTRKSQYRINDLYSRVLLSEPN-------------------MHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPVDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPKDGHLLLDGGYVNNLPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFESMAKAGRLGRFNQWFNKEPPKRVN---HASLNEYTFIDLAQIVCRLPETYAVNTAELFSEDEDCDGYISEPTTLNTDRRRIQVSRAGNSLSFSETEMDSDVELDLKLERKTDKSTQSSPPSNSRSDMRGKEEARHMSNWHWGVKHKDETGSGATEATKTQTGQEQELQQEQQDQGATAEQLVDKDKEENKENRSSPNNETKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04958-1", "uniprot_id": "NTE1_YEAST", "id": "Q04958-1", "name": "Lysophospholipase NTE1", "aln": "----------MRSMNCTTNNTNNTGQNTKNSLGSSFNSSNYTSYRFQTCLTDQIISEAQTWSLSSLFNFSWVVSYFVMGASRMIFRYG----WYLATLSLLRIPKWIFFKLHHVQFTLSFWLILFALAVIVFVTYTIMKERILSQYKRLTPEFLPLENTGKSGSSANINAASTQSAN-APPAIGSSTTGASSIIDSKKHSLKDGNENETFLSSYLDQFLSAIKIFGYLEKPVFHDLTKNMKTQKMDEGEILLLDSTIGFAIVVEGTLQLYHEVDHSDKDHGDETDHSDTDGLDDQDRDEEDEEEDDDIDNYDTKSCSSNLIDEEDESVGYIHLKNGLGNFQLLNTVKPGNPLTSLVSILNLFTHSMSSYGNSNFPSELSSPIDTTVSVNNMFCSSEQNFSNTDSMTNSTNSFPTFPSSMPKLVARAATDCTIGIIPPQSFAKLTAKYPRSASHIIQMVLTKLYHVTFQTAHDYLGLTKEIMDIEVLLNKSIVYELPYYLKEAVIRKFKTVDKSSGSADLEPKPKNSNASSKLKKPPKAKPSDGIIQSLKIANANANTSSNSLSLKPEFTHHPSSRHVVLGSRDQFNPGDLLSNVPLSRTMDILSPNPIHNNNRNKSNGINTSTSNQHKRSSRSSSNNASVHSKKFSSLSPELRNAQLSTSPLSLDNTSVHDHIHPSPVHLKGRVSPRPNLLPTTSFSAAQEETEDSALRMALVEAMLTYLGVNKSNMSVSSSSIANMSSLNSPQLNEMYSRRPSNASFLMSPHCTPSDISVASSFASPQTQPTMLRILPKEYTISNKRHNKSKSQDKKKPRAYKEELTPNLDFEDVKKDFAQGIQLKFFKKGTTIVEQN-ARGKGLFYIISGKVNVTTNSSSSVVSSMSKPEQVSAQSSHKGENPHHTQHLLYSVGSGGIVGYLSSLIGYKSFVNIVAKSDVYVGFLSSATLERLFDKYFLIYLRISDSLTKLLSSRLLKLDHALEWVHLRASETLFSQGDSANGIYVVLNGRLRQLQQQSLSNSNTSSEEVETQNIILGELAQGESFGEVEVLTAMNRYSTIVAVRDSELARIPRTLFELLALEHPSIMIRVSRLVAKKIVGDRTVPALTGDPLSIKENDFTSLIPPTKASYSSSLSHKPQNITSGTITFRTITILPITSGLPVEAFAMKLVQAFKQVGRTTIGLNQRTTLTHLGRHAFDRLSKLKQSGYFAELEEMYQTVVYISDTPVKSNWTRTCIAQGDCILLLADARSPSAEIGEYEKLLLNSKTTARTELILLHPERY-VEPGLTHKWLRYRPWVHSHHHIQFSLTGTTLMNEGKMHVLNNGALALMDKLIQTEFSRKTQQNISKLLPDSIKNTVENFSSRFMKSKRQYYTPVHRHKNDFLRLARILSGQAIGLVLGGGGARGISHLGVIQAIEEQGIPVDVIGGTSIGSFVGGLYAKDYDLVPIYGRVKKFAGRISSIWRMLTDLTWPVTSYTTGHEFNRGIWKTFGDTRIEDFWIQYYCNSTNITDSVQEIHSFGYAWRYIRASMSLAGLLPPLEE--NGSMLLDGGYVDNLPVTEMRARGCQTIFAVDVGSADDRTPMEYGDSLNGFWIIFNRWNPFSSHPNIPNMAEIQVRLGYVASVNALEKAKNTPGVVYVRPPIEEYATLDFSKFEEIYHVGVDYGRIFLQGLIDDDKMPYIPGSQETTLN--------SQVPEFLLHRRNSI----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : * * .:: * : : . : : .: . : . : **. : : . :.. :*. ::::*::***:* * :: .: *: :: . :: : : : * *. :: * *:.: **:*:::::: . : .:* .: :* :* : . * :::*::: :* :* . : ::****. *:.. . . : . . : . :: .: : : : . : :. . : ::: * : * . :. . .* :** *: * * .: :. . : : : .:: : * .. :. :*. : : *.*::* :.:..::: *.: :: :::*.**:*.: : :: : ** .:*: .* ** :* * :*: ****:**.::* : : .:* :: :: ::..:::*. .. . . *:: :* :*: .* :* ::: :* ..: *.. ** :: : : :.::.: *: .:* * :.. ** *: *.* *:::. . . . :*: *: : : .:*:**: * * * .**. *.* * *: *:::: .: .: : : :.** **** *:*::*.********** :::*:::*: : *:*:*::**.***:::*.*:..: . :.:::: : . ***:*:** :* ** * * * ***:*: *: :*:** * .:*. * * *:*:**:*:* :*** : :* :*:****::***. : * ::*:**** *: *** *.*:*::::: ** : :: ::.:** **.**..*. ** .*.: *:**.*: : *: *..*::* .** .* : : . : .* ", "identical_positions": 211, "similar_positions": 360, "identity": "11.31%" }, { "cls_id": "homologset.agr.FB:FBgn0003660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63024-1", "uniprot_id": "VAMP3_MOUSE", "id": "P63024-1", "name": "Vesicle-associated membrane protein 3", "aln": "MSTGV---------------PSGSSAATGSN--------------RRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGISVLVIIVIIIIVWCVS--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63025-1", "uniprot_id": "VAMP3_RAT", "id": "P63025-1", "name": "Vesicle-associated membrane protein 3", "aln": "MSTGV---------------PSGSSAATGSN--------------RRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGISVLVIIVIIIIVWCVS--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15836-1", "uniprot_id": "VAMP3_HUMAN", "id": "Q15836-1", "name": "Vesicle-associated membrane protein 3", "aln": "MST-------------------GPTAATGSN--------------RRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63044-1", "uniprot_id": "VAMP2_MOUSE", "id": "P63044-1", "name": "Vesicle-associated membrane protein 2", "aln": "MSATAATVPPAAP--AGEGGPPAPPPNLTSN--------------RRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63045-1", "uniprot_id": "VAMP2_RAT", "id": "P63045-1", "name": "Vesicle-associated membrane protein 2", "aln": "MSATAATVPPAAP--AGEGGPPAPPPNLTSN--------------RRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63027-1", "uniprot_id": "VAMP2_HUMAN", "id": "P63027-1", "name": "Vesicle-associated membrane protein 2", "aln": "MSATAATAPPAAP--AGEGGPPAPPPNLTSN--------------RRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62442-1", "uniprot_id": "VAMP1_MOUSE", "id": "Q62442-1", "name": "Vesicle-associated membrane protein 1", "aln": "MSAPAQPPAEGTEGAAPGGGPPGPPPNMTSN--------------RRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23763-1", "uniprot_id": "VAMP1_HUMAN", "id": "P23763-1", "name": "Vesicle-associated membrane protein 1", "aln": "MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSN--------------RRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63666-1", "uniprot_id": "VAMP1_RAT", "id": "Q63666-1", "name": "Vesicle-associated membrane protein 1", "aln": "MSAPAQPPAEGTEGAAPGGGPPGPPPNTTSN--------------RRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASVFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYIFT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18489-1", "uniprot_id": "SYB_DROME", "id": "P18489-1", "name": "Synaptobrevin", "aln": "MENNEAPSPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLVSVWPSSSDSGSGGGNKAITQAPPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31109-1", "uniprot_id": "SNC1_YEAST", "id": "P31109-1", "name": "Synaptobrevin homolog 1", "aln": "MSSSTPFDPYALS-----EHDEERPQNVQSK--------------SRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33328-1", "uniprot_id": "SNC2_YEAST", "id": "P33328-1", "name": "Synaptobrevin homolog 2", "aln": "MSSSVPYDPYVPP-----EESNSG-ANPNSQ--------------NKTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKMRMCLFLVVIILLVVIIVPIVVHFS-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : : ::::.*.*:* *::** **.::*:.: ::** * .*. *: * :::: *: : ** : :::::::: ", "identical_positions": 19, "similar_positions": 39, "identity": "12.5%" }, { "cls_id": "homologset.agr.FB:FBgn0003676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28480-1", "uniprot_id": "TCPA_RAT", "id": "P28480-1", "name": "T-complex protein 1 subunit alpha", "aln": "--------MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDIRGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMLKRIV--NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGASILSTLANLEGEETFEATMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGGYENAVHSGALDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11983-1", "uniprot_id": "TCPA_MOUSE", "id": "P11983-1", "name": "T-complex protein 1 subunit alpha", "aln": "--------MEGPLSVFGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIV--NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYENAVHSGALDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17987-1", "uniprot_id": "TCPA_HUMAN", "id": "P17987-1", "name": "T-complex protein 1 subunit alpha", "aln": "--------MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIV--NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVN-PE---RKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12613-1", "uniprot_id": "TCPA_DROME", "id": "P12613-1", "name": "T-complex protein 1 subunit alpha", "aln": "-----MSTLASPLSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGKSARESVLIPGYALNCTIASQQMPKKIV--NAKIACLDFSLQKTKMKMGVQVLINDPDKLEAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDLVAKLRSYHNSSQTK-PE---RSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITILRIDDMIKLNPEDKSGK--SYADACAAGELDG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12612-1", "uniprot_id": "TCPA_YEAST", "id": "P12612-1", "name": "T-complex protein 1 subunit alpha", "aln": "MSQLFNNSRSDTLFLGGEKISGDDIRNQNVLATMAVANVVKSSLGPVGLDKMLVDDIGDFTVTNDGATILSLLDVQHPAGKILVELAQQQDREIGDGTTSVVIIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINEVLSTSVDTLGKETLINIAKTSMSSKIIGADSDFFSNMVVDALLAVKTQNSKGEIKYPVKAVNVLKAHGKSATESLLVPGYALNCTVASQAMPKRIAGGNVKIACLDLNLQKARMAMGVQINIDDPEQLEQIRKREAGIVLERVKKIIDAGAQVVLTTKGIDDLCLKEFVEAKIMGVRRCKKEDLRRIARATGATLVSSMSNLEGEETFESSYLGLCDEVVQAKFSDDECILIKGTSKHSSSSIILRGANDYSLDEMERSLHDSLSVVKRTLESGNVVPGGGCVEAALNIYLDNFATTVGSREQLAIAEFAAALLIIPKTLAVNAAKDSSELVAKLRSYHAASQMAKPEDVKRRSYRNYGLDLIRGKIVDEIHAGVLEPTISKVKSLKSALEACVAILRIDTMITVDPEPPKEDPHDH-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* : * : :* :*.***:*: :::*:****:***************.*:******** **:*:***.*:* ***: **.*:*********:*:****.*:****:*****::*:*:*:* :** ::*.* * .* **:: *** *********** :.::*: ***** ::* : :*: *.::::*:*****:* **:*: ******.:.** * *:*. *.******:.***::* :***: * **::*: ** ** .*. **:: *: :*.:*:*.: *:**: :* **** *.*** * **: :*:*:**:::::::*::***:*: : :* . **.* ::.*** ****.*. ::::******.**: ******:**:*.****.** .**.***.*****.***:*:**::.*********** :**:**:**:****:*:::******::* :* ** * . : **** .* *: :***:**:: *:**** * **.::***** :*.:.** . . .: ", "identical_positions": 295, "similar_positions": 163, "identity": "51.75%" }, { "cls_id": "homologset.agr.FB:FBgn0003687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HB1-1", "uniprot_id": "Q66HB1_RAT", "id": "Q66HB1-1", "name": "", "aln": "--MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPVQNTNSLSILEEQQRQQQQQQQQQQQQQQ---------------------QAVATAAASVQQSTSQQPTQGASGQTPQLFHS----QTLTTAPLPGTTPLYPSP---------------MTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29037-1", "uniprot_id": "TBP_MOUSE", "id": "P29037-1", "name": "TATA-box-binding protein", "aln": "--MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQ-----------------------QAVATAAASVQQSTSQQPTQGASGQTPQLFHS----QTLTTAPLPGTTPLYPSP---------------MTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20226-1", "uniprot_id": "TBP_HUMAN", "id": "P20226-1", "name": "TATA-box-binding protein", "aln": "--MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHS----QTLTTAPLPGTTPLYPSP---------------MTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXL3-1", "uniprot_id": "TBP_DANRE", "id": "Q7SXL3-1", "name": "TATA-box-binding protein", "aln": "--MEQNNSLPPFAQGLASPQGAMTPGLPIFSPMMPYGTGLTPQPVQNSNSLSLLEEQQRQQQQQQAASQQQ---------------------------------------GGMVGGSGQTPQLYHSTQ--AVSTTTALPGNTPLYTTP---------------LTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRGEIYEAFENIYPILKGFRKTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13393-1", "uniprot_id": "TBP_YEAST", "id": "P13393-1", "name": "TATA-box-binding protein", "aln": "-----MADE--------ERLKEFKEANKIVFDP--------------------NTRQVWENQNRDGT---------------------------KPATTFQSEED----------------------------IKRAAPESEKDT-------------------------------SATSGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSS-YEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P20227-1", "uniprot_id": "TBP_DROME", "id": "P20227-1", "name": "TATA-box-binding protein", "aln": "--MDQMLSPNFSIPSIGTPLHQMEADQQIVANPVYHPPAVSQPDSLMPAPGSSSVQHQQQQQQSDASGGSGLFGHEPSLPLAHKQMQ-----SYQPSASYQQQQQQQQLQSQAPGGGGSTPQSMMQPQTPQSMMAHMMPMSERSVGGSGAGGGGDALSNIHQTMGPSTPMTPATPGSADPGIVPQLQNIVSTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEDDSRLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHCNFSS-YEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDKIFPILKKFKKQS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q1JPY4-1", "uniprot_id": "TBPL2_DANRE", "id": "Q1JPY4-1", "name": "TATA box-binding protein-like 2", "aln": "----MNMDEEASLESYFDQTIAGSSDYIFEGDLGLQGSTSQLQDSSFLSSLASQEKDLTEDLDLSFLPD-------------------------ELSTQDEPSQVEKESKNEDSGIYTDCPQKEST---QADIDTSNSAQNTSQFNLP---------------MTPMTPMTPMTPVAESSGIIPQLQNIVSTVNLACPLDLKSIALQARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVCFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFRKQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6SJ95-1", "uniprot_id": "TBPL2_MOUSE", "id": "Q6SJ95-1", "name": "TATA box-binding protein-like 2", "aln": "MVGSLIMEEDIYLDLFLDPYTIQDDFPPAMSQLFSPGVPLDMHSL-PSNPETVFHPHLGGVKKASTDFSSVDLSFLPDELTQENRDQTVTGNKLASEESCRTRDRQSQLQLPDEHGSELNLNSNSSPDPQSCLCFDDAHSNQPSPETPNSNA---------LPVALIASMMPMNPVPGFSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEEESRLAARKYARVVQKLGFPVRFFNFKIQNMVGSCDVKFPIRLEILALTHRQFSSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6H909-1", "uniprot_id": "TBPL2_RAT", "id": "A6H909-1", "name": "TATA box-binding protein-like 2", "aln": "------MEEDMYVDIFLDPYTFQDDFPPATSQLFSPGAPLDVHPLNPSNPETVFHSHLGAVKKAPSDFSSVDLSFLPDELTQENKDRTVTGNKVTNEESFRTQDWQSQLQLPDEQGSGLNLNSNSSPDTQSCLCSHDADSNQLSSETPNSNA---------LPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARVVQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSS-YEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6SJ96-1", "uniprot_id": "TBPL2_HUMAN", "id": "Q6SJ96-1", "name": "TATA box-binding protein-like 2", "aln": "-----MEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNP-EVKETSGDFSSVDLSFLPDEVTQENKDQPVIS-KHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDS---------LSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSS-YEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . **:* ***:*:*..* * ***:.:**.*:*:*****************:******:***:* ******::*:**:*****::**:**..:* :*****:*.**** ****** *.::* *** ***********:*::*::*****.***:****** * ***:**: ::*:*. *:* ", "identical_positions": 121, "similar_positions": 48, "identity": "33.52%" }, { "cls_id": "homologset.agr.FB:FBgn0003714", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQX3-1", "uniprot_id": "D3ZQX3_RAT", "id": "D3ZQX3-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MSWPGLLHGLTTS---LSRGLALAPQLWATRSMATLNQMHR-LGRPKEPPKRLGP-TEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTGKEAVCFIPGEGHTLQEHHVVLVEGGRTQDLPGVKLKVVRGKYDCGHVQ-----------KKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35680-1", "uniprot_id": "RT12_MOUSE", "id": "O35680-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MSWPGLLYGLTTS---LSRGLALAPQLWAARSMATLNQMHR-LGPRKEPPKRLGP-TEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTGKEAVCFIPGEGHTLQEHHVVLVEGGRTQDLPGVKLKVVRGKYDCGHVQ-----------KKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15235-1", "uniprot_id": "RT12_HUMAN", "id": "O15235-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MSWSGLLHGLNTS---LTCGPALVPRLWATCSMATLNQMHR-LGPPKRPPRKLGP-TEGRPQLKGVVLCTFTRKPKKPNSANRKCCRVRLSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKLTVVRGKYDCGHVQ-----------KK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8G8-1", "uniprot_id": "E7F8G8_DANRE", "id": "E7F8G8-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MAFLGSLKPMLSSALQASRSVSLWSAPLFSRTMATLNQMHR-KGKPPPPRRKISA-TFGHPQLKAVVLKTMIRKPKKPNSANRKCAQVRLSNGQEAVVYIPGEGHNLQEHNVVLVQGGRTQDLPGVKLAVIRGKYDCAHVV-----------KKKQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10735-1", "uniprot_id": "RT12_DROME", "id": "P10735-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MNFLRQSFGITKQ---LASQAIQCSYETAVRGMASLQQMHR-SGPHIKTRPPRQP-LDGKPFAKGVVLKTLIKKPKKPNSANRKCVLVRLSTGKEMVAYIPGIGHNLQEHNIVLCRVGRLQDVPGVKLKAVRGVYDLAHVV-----------KKSQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53732-1", "uniprot_id": "RT12_YEAST", "id": "P53732-1", "name": "Small ribosomal subunit protein uS12m", "aln": "MLSRFMSNTWCTP---LRQAQRLFSSTTTMQ--ATLNQIKRGSGPPRRKKISTAPQLDQCPQRKGVVLRVMVLKPKKPNSAQRKACRVRLTNGNVVSAYIPGEGHDAQEHSIVYVRGGRCQDLPGVKYHVIRGAGDLSGVVNRISSRSKYGAKKPSKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *:*:*::* * . * *.*** .: ********:**. ***:.*. :*** ** *** :* . ** **:**** .:** * . * ** ", "identical_positions": 48, "similar_positions": 22, "identity": "30.38%" }, { "cls_id": "homologset.agr.FB:FBgn0003716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78EA7-1", "uniprot_id": "BMR1A_RAT", "id": "Q78EA7-1", "name": "Bone morphogenetic protein receptor type-1A", "aln": "----------------MTQLYTYIR----LLGACLFIISHVQGQNLDSMLHGTGMKSDVDQKKPENG--VTLAPEDTLPFLKCYCSGHCPDDAINNTCITN--GHCFAIIEEDDQGETTLTS-----GCMKYE--GSDFQCKDSPKAQLR-RTIECCR-TNLCNQYLQPTLPPVVIG-----PFFDGSVRWLAVLISMAVCIVAMIVFSSCFCYKHYCKSISSRGRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDIPLNTRVGTRRYMAPEVLDESLSKNHFQPYIMADIYSFGLIIWEMARRCIT------GGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36895-1", "uniprot_id": "BMR1A_MOUSE", "id": "P36895-1", "name": "Bone morphogenetic protein receptor type-1A", "aln": "----------------MTQLYTYIR----LLGACLFIISHVQGQNLDSMLHGTGMKSDLDQKKPENG--VTLAPEDTLPFLKCYCSGHCPDDAINNTCITN--GHCFAIIEEDDQGETTLTS-----GCMKYE--GSDFQCKDSPKAQLR-RTIECCR-TNLCNQYLQPTLPPVVIG-----PFFDGSIRWLVVLISMAVCIVAMIIFSSCFCYKHYCKSISSRGRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDIPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMARRCIT------GGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36894-1", "uniprot_id": "BMR1A_HUMAN", "id": "P36894-1", "name": "Bone morphogenetic protein receptor type-1A", "aln": "----------------MPQLYIYIR----LLGAYLFIISRVQGQNLDSMLHGTGMKSDSDQKKSENG--VTLAPEDTLPFLKCYCSGHCPDDAINNTCITN--GHCFAIIEEDDQGETTLAS-----GCMKYE--GSDFQCKDSPKAQLR-RTIECCR-TNLCNQYLQPTLPPVVIG-----PFFDGSIRWLVLLISMAVCIIAMIIFSSCFCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMARRCIT------GGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2A7-1", "uniprot_id": "A0A8M1N2A7_DANRE", "id": "A0A8M1N2A7-1", "name": "receptor protein serine/threonine kinase", "aln": "---------------MMKSTFTIIVFG-VLVAAVLLSPLAEGGQNPDYMLHGTGVKPGSDPRRAQAGDGSTVAPEDAARFLSCYCSGHCPEDATNNTCETN--GHCFAIIEEDEHGEAMLTS-----GCMKYE--GSHFQCKDSPNAQTR-RTIECCS-TDFCNRDLQPTLPPPIPGKP---PFWN--AHLLAFLISVTVCCFTLVAITIVCYYR--FKLQTGRRHYQRDLGPIEAFIPAGESLKDLISQS-STGSGSGLPLLVQRTIAKHIQMVRQIGKGRYGEVWLGRWRGENVAVKVFFTREEASWFRETEIYQTVLMRHENILGFIAADIKGTGTFTQLFLITDYHENGSLCDYLKYTTLDTQALLRLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGTCCIADLGLAVKYNSDTNEVDVPLSTRMGTRRYMAPEVLDETLNKNQFQAYIMADIYSYGLIVWEMARRCVT------GGIVEEYQLPYWDMVPSEPSYEDMREVVCVKSMRPVVSNRWNSDECLRVMLKLMSECWAHNPASRLTALRVKKSLAKMVESQDIKI-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0R3J4-1", "uniprot_id": "M0R3J4_RAT", "id": "M0R3J4-1", "name": "Serine/threonine-protein kinase receptor", "aln": "------------------------------------------------MLLRSSGKLNVGTKKEDGE---STAPTARPKVLRCKCHHHCPEDSVNNICSTD--GYCFTMIEEDDSGTPVVTS-----GCLGLE--GSDFQCRDTPIPHQR-RSIECCTERNECNKDLHPTLPPLKDR-----DFVDGPIHHKALLISVTVCSLLLVLIILFCYFR--YKRQEARPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRTHFQSYIMADMYSFGLILWEIARRCVS------GGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36898-1", "uniprot_id": "BMR1B_MOUSE", "id": "P36898-1", "name": "Bone morphogenetic protein receptor type-1B", "aln": "------------------------------------------------MLLRSSGKLNVGTKKEDGE---STAPTPRPKILRCKCHHHCPEDSVNNICSTD--GYCFTMIEEDDSGMPVVTS-----GCLGLE--GSDFQCRDTPIPHQR-RSIECCTERNECNKDLHPTLPPLKDR-----DFVDGPIHHKALLISVTVCSLLLVLIILFCYFR--YKRQEARPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVS------GGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVKKTLAKMSESQDIKL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00238-1", "uniprot_id": "BMR1B_HUMAN", "id": "O00238-1", "name": "Bone morphogenetic protein receptor type-1B", "aln": "------------------------------------------------MLLRSAGKLNVGTKKEDGE---STAPTPRPKVLRCKCHHHCPEDSVNNICSTD--GYCFTMIEEDDSGLPVVTS-----GCLGLE--GSDFQCRDTPIPHQR-RSIECCTERNECNKDLHPTLPPLKNR-----DFVDGPIHHRALLISVTVCSLLLVLIILFCYFR--YKRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVS------GGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJN6-1", "uniprot_id": "A0A8M9PJN6_DANRE", "id": "A0A8M9PJN6-1", "name": "Serine/threonine-protein kinase receptor", "aln": "----------------MDLYRSCLRWLCVLLIGLLGLVEENLANVLDSMLLRNSGKVEE--RRETG----SDAPALPQRFLWCYCYHHCPEDSTNNTCRTD--GYCFTMVEEE-GGAAVVTS-----GCLGLV--GSEFQCRDTGNSKQR-RALECCTDQDYCNRDLHPTLPPLRTP-----SYVVGDIHHIALLISVSVCSFILTFIIIFCYFR--YKRHELAPRYSLGLHPDESFIPAGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVTQIGKGRYGEVWMGRWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKCTTLDSRAMLKLAYSSVSGLCHLHTEIFGTQGKPAIAHRDLKSKNILVKRNGACCIADLGLAVKFISDTNEVDIPLNTRVGTKRFMAPEVLDETLNRNHFQSYIMADMYSFGLILWEISRRCVT------GGIVEEYQLPYHDHVPNDPSYEDMREVVCIKRIRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMT1-1", "uniprot_id": "Q9VMT1_DROME", "id": "Q9VMT1-1", "name": "receptor protein serine/threonine kinase", "aln": "MRLQLVALELQATSGTADGLFEEIALEALTRSEFSANVQPDVEAMAAAALSGMEMGSGPGSEGYEDADNEKSKTVENARSLTCYCDGSCPDNVSNGTCETRPGGSCFSAVQQLYDETTGMYEEERTYGCMPPEDNGGFLMCKVAAVPHLHGKNIVCCDKEDFCNRDLYPTYTPKLTTPAPDLPVSSESLHTLAVFGSIIISLSVFMLIVASLCFT--YKRREKLRKQPRLIN--SMCNSQLSPLSQLVEQS--SGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWTQMLLITDYHEMGSLHDYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGTPGKPAIAHRDIKSKNILVKRNGQCAIADFGLAVKYNSELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFEEFKRADMYSVGLVLWEMTRRCYTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATVSKIMQECWHPNPTVRLTALRVKKTLGRLETDCLIDVPIKIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . * * * **:: *. * * * **: ::: . : . **: *. : *: : .: : : : ** : **: * ** .* : ..: *: :. : : : * : : . . ..* :*:.** :****************:**** :*********:.:**.*.****.*** *******************:************.*::**: ******* *** *:*. :.::.: : **:* ..**.*** **:.* *********:******:*:** *.***:*****: *: : :.:. ..*:**:*:*.****.: *. .:*: : **:** **::**::*** : *:* *** : **.:*::***: :**:* :** ...**..*: * : *:* *** **: ******:**:*.:: . :.: ", "identical_positions": 212, "similar_positions": 133, "identity": "36.49%" }, { "cls_id": "homologset.agr.FB:FBgn0003719", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M280-1", "uniprot_id": "F1M280_RAT", "id": "F1M280-1", "name": "Metalloendopeptidase", "aln": "--MPQATALG----TLV-LLLLLPLLLRAEVTGDHSDVALDYGALEGEEGTEQEQQLQYHDPCKAAVFWGDIALDEDDLKLFHIDKAEDWTKPSMERMGHDTGGLEETSAR-WPNDTASNSSIQALRKDGKDSTTLLPGPGTSNT------TAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFIERTD--EESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTSGNFSAPGFPNG------------------------YPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVEIRDGYWRKAPLLGRFCGDKVPEPLVSSDSRLWVEFRSSSSILG-KGFFAVYEAMCGGDITKDAGQ-IQSPNYPDDYRPSKECVWRITVADGFHVGLTFQSFEIERHDSCAYDYLEIRDGPTEESALIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAASFFKEVDECSWPDHGGCEQRCVNTLGSYTCACDPGYELAANKKTCEVA-CGGFI--TKLNGTITSPGWPKEYPTNKNCVWQVVAPMQYRISLQFEAFELEGN----DVCKYDFVEVRSGLSPD-AKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEVEQHQECAYDHLELYDGTDSSAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSQAHCDWVIVAEDGYGVELVFRTFEVEEEADCGYDYLEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIHFHTDDTINKKGFHARYTSTK------------------FQDALHMRK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVM6-1", "uniprot_id": "TLL2_MOUSE", "id": "Q9WVM6-1", "name": "Tolloid-like protein 2", "aln": "--MPLATTLG----TLV-LLLLLPLPRGAEVTGDHSNVALDYGALEGEEGT--EQQLHYHDPCKAAVFWGDIALDEDDLKLFHIDKAEDWTKPSIDKPGHDTGGLEETSAR-WPNDTASNASIQAPRKDGKDATTFLPNPGTSNT------TAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTD--EESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNG------------------------YPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVEIRDGYWRKAPLLGRFCGDKIPESLVSSDSRLWVEFRSSSSSLG-KGFFAVYEAMCGGDITKDAGQ-IQSPNYPDDYRPSKECVWRITVPDGFHVGLTFQSFEIERHDSCAYDYLEIRDGPTEDSTLIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEQRCVNTLGSYTCACDPGYELAADKKTCEVA-CGGFI--TKLNGTITSPGWPKEYPTNKNCVWQVVAPVQYRISLQFEAFELEGN----DVCKYDFVEVRSGLSPD-AKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEIEQHQECAYDHLELYDGTDSLAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGYDFMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYTSTK------------------FQDALHMRK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6L7-1", "uniprot_id": "TLL2_HUMAN", "id": "Q9Y6L7-1", "name": "Tolloid-like protein 2", "aln": "--MPRATALG----ALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGT-EQQLEHYHDPCKAAVFWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAGKDGRENTTLLHSPGTLHA------AAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTD--EESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNG------------------------YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDAGQ-IQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVA-CGGFI--TKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGN----DVCKYDFVEVRSGLSPD-AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK------------------FQDALHMKK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M798-1", "uniprot_id": "F1M798_RAT", "id": "F1M798-1", "name": "Metalloendopeptidase", "aln": "--MPGVARPPLPLLSLP-LLLLLLLPR-AGRPLDLADYTYDLGEEDA------PELLNYKDPCKAAAFLGDIALDEEDLRAFRVQQAAVLRQQTAQRSSIKAA--GNSSALGRQSTSGQPQRGSRGRWRSR--------------------------PRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD--EDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG------------------------YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDNGH-IQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFL--TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN----DVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTK------------------FQDTLHSRK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98063-1", "uniprot_id": "BMP1_MOUSE", "id": "P98063-1", "name": "Bone morphogenetic protein 1", "aln": "--MPGVARPPLPLLSLPLLLLLLLLPR-AGRPLDLADYTYDLGEEDA------PELLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAAVLRQQTARRPSIKAA--GNSSALGGQGTSGQPQRESRGRWRGR--------------------------PRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD--EDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG------------------------YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDNGH-IQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFL--TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN----DVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYIELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTK------------------FQDTLHSRK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13497-1", "uniprot_id": "BMP1_HUMAN", "id": "P13497-1", "name": "Bone morphogenetic protein 1", "aln": "--MPGVAR-------LPLLLGLLLLPR-PGRPLDLADYTYDLAEEDD------SEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGR--------------------------SRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD--EDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG------------------------YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDYGH-IQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFL--TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGN----DVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTK------------------FQDTLHSRK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z8U5-1", "uniprot_id": "D3Z8U5_RAT", "id": "D3Z8U5-1", "name": "Metalloendopeptidase", "aln": "--MGLQALSPRM-LLWLVVSGIVFSRELWVCTGLDYDYTFDGNEEDK------TEPIDYKDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQGPFGKLGHITGGFGDHGMPKKRGALYQLIDRIRRIGSGLEQNNTTKGKAPPKL------SEQNEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTERSD--EESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESSGNLSSPGFPNG------------------------YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIRKNEGQ-IQSPNYPDDYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYDHLEVRDGNSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKADRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAA-CGGLL--TKLNGTITTPGWPKEYPPNKNCVWQVIAPSQYRISVKFEFFELEGN----EVCKYDYVEIWSGLSSE-SKLHGKFCGADVPEVITSHFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYTCQCRNGFVLHENKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWAISAIPGHRIKLAFNEFEVEQHQECAYDHLEIFDGQTEKSPILGRLCGSKIPDPLMATGNEMFIRFISDASVQRKGFQATHSTECGGRLKAERKPKDLYSHAQFGDNNYPGQLDCEWLLVSEQGSRLELSFQTFEVEEEADCGYDYVEVFDGLNSKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSIR------------------YPETMHAEN-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62381-1", "uniprot_id": "TLL1_MOUSE", "id": "Q62381-1", "name": "Tolloid-like protein 1", "aln": "--MGLQALSPRM-LLWLVVSGIVFSRVLWVCAGLDYDYTFDGNEEDK------TEPIDYKDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQSPFGKLGHITGGFGDHGMPKKRGALYQLIERIRRIGSGLEQNNTMKGKAPPKL------SEQSEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTERSD--EESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESSGNLSSPGFPNG------------------------YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIRKNEGQ-IQSPNYPDDYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYDHLEVRDGASENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAA-CGGLL--TKLNGTITTPGWPKEYPPNKNCVWQVIAPSQYRISVKFEFFELEGN----EVCKYDYVEIWSGPSSE-SKLHGKFCGADIPEVMTSHFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYTCQCRNGFVLHENKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWVISAIPGHRITLAFNEFEVEQHQECAYDHLEIFDGETEKSPILGRLCGSKIPDPLMATGNEMFIRFISDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQLDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVEVFDGLSSKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSIR------------------YPETMHAKN-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43897-1", "uniprot_id": "TLL1_HUMAN", "id": "O43897-1", "name": "Tolloid-like protein 1", "aln": "--MGLGTLSPRM-LVWLVASGIVFYGELWVCAGLDYDYTFDGNEEDK------TETIDYKDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQNPFGNLGHTTGGLGDHAMSKKRGALYQLIDRIRRIGFGLEQNNTVKGKVPLQF------SGQNEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSD--EESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESNGNLSSPGFPNG------------------------YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIRKNEGQ-IQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAA-CGGLL--TKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGN----EVCKYDYVEIWSGLSSE-SKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIR------------------YPDTTHTKK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57460-1", "uniprot_id": "TLL1_DANRE", "id": "O57460-1", "name": "Dorsal-ventral patterning tolloid-like protein 1", "aln": "MDYLYSALTSKMNWIALLLAGLTFCCKVSVHSCLDYDDSYDYYEEEK------TETIDYKDPCKAAVFWGDIALDDEDLKMFHIDGTIDLKQQTHGRQGHTSGGLGEHVPTKKRGSLYLLLDRIRRLGFESWPVNSSKDVSSIKTGIRRVNSARNVKSRVPRAATSRAEKIWPGGVIPYVIGGNFTGSQRAMLKQAMRHWEKQTCVTFIEKTD--EESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVTIIRDNIQPGQEYNFIKMEPGDVNSLGEPYDFDSIMHYARNTFSRGMFLDTILPSRDENGVRPAIGQRTRLSKGDISQAKKLYRCPACGETLQDSVGNFSSPGYPNG------------------------YPSYTHCVWRISVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKAPLLGRFCGDKIPEVLVSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEISKDSGQ-IQSPNYPDDYRPSKECVWRITVSEGYSVGLSFQVFEIERHDSCAYDYLEVRDGLSENSPLIGRFCGYDKPEDIRSTSNNLWMKFVSDGTVNKAGFAANFFKEEDECLKPDNGGCEQRCVNTLGSFKCACDPGYELAPDKKSCEAA-CGGLL--TKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISMQFEAFELEGN----EVCKYDYVEVRSGLSSD-SKLHGKYCGTEVPEVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECINTIGSYVCQCRNGFILHENKHDCKEAECEHKIHSTTGTISSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQHQECAYDHLEAFDGDSDKTPILSRLCGNKIPEPLISTGNKMYLRFISDASVQRKGFQATHSTECGGRLKAEARQKNLYSHAQFGDNNYPGHTDCEWLIVAESGYGIELTFTTFEVEEEADCGYDYIELYDGYDTGAHKIGRFCGSGPREELYSAGDAVLIHFHSDDTISKKGFHIRYTSTK------------------FQEALHTRK-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B1Y0-1", "uniprot_id": "A0A8M2B1Y0_DANRE", "id": "A0A8M2B1Y0-1", "name": "Metalloendopeptidase", "aln": "------------------MNSPWTRVLVLIFCLLTVDTIYQTGPGES-------DEVDYKDPCKAVAFLGDIALDEEDLRFLKAHYMHATENESSGSSKPDSVNRSSANRNAKDEPVLANQSILRR----------------------------------RRAATARPERVWPNGIIPYIISGNFTGSQRAIFKQAMRHWEKHTCVTFVERSV--EESYIVFTLRPCGCCSFVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVDIFRENIQPGQEYNFIKMEPDDVDSLGEVYDFDSIMHYARNTFSRGIYLDTMLPKYDVDGVRPPIGQRTRLSKGDIAQARKLYRCPRCGESLQDSAGNFSSPGFPNG------------------------YAAYLHCIWRISVTPGEKIVLNFTSMDLYRSNLCWYDYVEVRDGYGRSAPLKGRICGDQLPEAIVSTDSELWIEFRSTSNWVG-KGFSAVYEAICGGEVRRDSGQ-IESPNYPDDYRPNKACIWKIVVPEGFHVGLVFQSFEIEKHDNCAYDYLEVRDGDSESSPLLGRFCGYEKPDDFKSSSNQLWMKFVSDGSVNKAGFAANFFKEIDECSRPDNAHCEQRCINTLGSFHCACDPGFELAPDRRSCAAAACGGFI--SKLNGSFTSPGWPQEYPPNKNCVWQLIAPVQYRITLLFDAFEMEGN----DVCKYDYVEVHSGLSAD-GKLHGKFCGTEKPEAITSQLNSMSVEFKSDNTVSKRGFKAQFFSDMDECSRENGGCQHECVNTFGSYSCQCRSGFVLHSNKHDCKEVGCDQAITSVSGLITSPNWPDKYPSKKACTWTLSTTPGHRIKLAFEEIDMEAHQECAYDHLEIYDGQNGRATSVGRFCGSKKPSPVISSSNTMFLRFFSDNSVQKRGFKASHSAECGGSLKAEIKTKDLYSHAQFGDNNYPGASDCQWVISAEKGYGVELIFHTFEIEEEADCGYDYVELFDGGDVKAPRLGRYCGSGPPEEIYSAGDAIVIKFHSDDTINKKGFHVRYTSTK------------------FQDTLHTSK-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25723-1", "uniprot_id": "TLD_DROME", "id": "P25723-1", "name": "Dorsal-ventral patterning protein tolloid", "aln": "--MKGMRLMPMKMKAKLVVLSVGALWMMMFFLVDYAEGRRLSQLPES------ECDFDFKEQPEDFFGILDSSLVPPKEPKDDIYQLKTTRQHS-GRRRKQSHKSQNKAALRLPPPFLWTDDAVDVLQHSHSPTLNGQP-----------------IQRRRRAVTVRKERTWDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKNGNGRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKCASCGRTYQQNSGHIVSPHFIYSGNGVLSEFEGSGDAGEDPSAESEFDASLTNCEWRITATNGEKVILHLQQLHLMSSDDCTQDYLEIRDGYWHKSPLVRRICGNVSGEVITTQTSRMLLNYVNRNAAKGYRGFKARFEVVCGGDLKLTKDQSIDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAYDFVEIRDGNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTDHG-CQHLCINTLGSYQCGCRAGYELQANGKTCEDA-CGGVVDATKSNGSLYSPSYPDVYPNSKQCVWEVVAPPNHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCGHELPPVVNSEQSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHRCRNTFGSYQCSCRNGYTLAENGHNCTETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRKGFKATFVSECGGYLRATNHSQTFYSHPRYGSRPYKRNMYCDWRIQADPESSVKIRFLHFEIEYSERCDYDYLEITEEGYSMNTIHGRFCGKHKPPIIISNSDTLLLRFQTDESNSLRGFAISFMAVDPPEDSVGEDFDAVTPFPGYLKSMYSSETGSDHLLPPSRLI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .::: : * :* . . . : . **.* * *: * *:**: *. *:*:::*:::*******: **:.* *: . .:* *: : *****::*:.*.* *.****:**:****: *****.:** ***:* *** *: * : ** ****** :. :*. **::******:*:**:. :***: * * : :*** ***:*** **. **:*. **.: *:. *:: :* : . .: :* **::.* ***::*:: :.* * * **:*:***: :.:** *:**. :.: *.: ::: . . * :** * :*. ***:: .: *:***** ** * * *:*:* ..:.. *.* ** **:*:**.****.:*:*** ..* *:*::** . * .:: :. ::::****.:::* **:. :: : *** .:.. *:: *:*****: *.* .*:** .: : * * ***.: :* **:: :*.:*. ** .*:*:*:::** :: : : *. *: **. *:**:: : * : * * :** : * .:.*. . : :** **.**.: ** *:*. * ***: :*****: * **:*** * **.*: * .* *:*.*. * : : * : ***:*:.** . * * : : ***: ::* ::::* : ** **:: :** :. :. **.: * . ::: . ::: : :* .:*::**:* . :**** ::* : : :***.::*.. * *:* : :: ::: * **:* . *.**::* : **:**. : * .* :::*::*:: . :** : : : .: : : ", "identical_positions": 320, "similar_positions": 302, "identity": "29.22%" }, { "cls_id": "homologset.agr.FB:FBgn0003720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R4V9-1", "uniprot_id": "M0R4V9_RAT", "id": "M0R4V9-1", "name": "Nuclear receptor subfamily 2 group E member 1", "aln": "MSKPAGS-----------------TSRIL-DIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHK-------------EDNGAAAHFPSAALPAP--------------AFFTAVTQLEPHGLELTAVSATPERQTLVSLAQPTPKYPHEVN--GTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNSDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVP---------------THSGS-------ELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64104-1", "uniprot_id": "NR2E1_MOUSE", "id": "Q64104-1", "name": "Nuclear receptor subfamily 2 group E member 1", "aln": "MSKPAGS-----------------TSRIL-DIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHK-------------EDNGAAAHFPSTALPAP--------------AFFTAVTQLEPHGLELAAVSATPERQTLVSLAQPTPKYPHEVN--GTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNTDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVP---------------THSGS-------ELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y466-1", "uniprot_id": "NR2E1_HUMAN", "id": "Q9Y466-1", "name": "Nuclear receptor subfamily 2 group E member 1", "aln": "MSKPAGS-----------------TSRIL-DIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHK-------------EENGAAAHFPSAALPAP--------------AFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVN--GTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVP---------------THSGS-------ELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18102-1", "uniprot_id": "TLL_DROME", "id": "P18102-1", "name": "Protein tailless", "aln": "MQSSEGSPDMMDQKYNSVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLLFVY--ESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDMYSQRKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*... ** :**** .:***** *:*******:******:*********.* ***** :** * **************:**:**.*************.**:*:::*:* . :..* : **...:* * ** .. : .*.:. *. * :* .: .**. * : : . * :*:* : *:**. ** .::* *** **: *.: ***:***::*:*:*:*.:**: :*:: ** * : :*:: : :. : *::*:***: :: :*.:*:**: **:.* *: * * *** * *.: ::. :**::::*: :*:.**: :*:** ** .** :: ::.:*. ****:**:****::.*.**:****.. .*", "identical_positions": 178, "similar_positions": 125, "identity": "39.21%" }, { "cls_id": "homologset.agr.FB:FBgn0003721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63610-1", "uniprot_id": "TPM3_RAT", "id": "Q63610-1", "name": "Tropomyosin alpha-3 chain", "aln": "MAGSTTIEAVKRKIQVLQQQADDAEERAER---------------------------------------------------------------LQREVEGERRAREQ---------------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z2H9-1", "uniprot_id": "D3Z2H9_MOUSE", "id": "D3Z2H9-1", "name": "", "aln": "MAGTTTIEAVKRKIQVLQQQADDAEERAER---------------------------------------------------------------LQQEVEGERRARKQ---------------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IRU2-1", "uniprot_id": "TPM4_MOUSE", "id": "Q6IRU2-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADDAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESERGMKVIENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09495-1", "uniprot_id": "TPM4_RAT", "id": "P09495-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADDAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDAAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKSSDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67936-1", "uniprot_id": "TPM4_HUMAN", "id": "P67936-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADEAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13104-1", "uniprot_id": "TPM1_DANRE", "id": "P13104-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAETDKKAAEERSK------------------------------------------QLEDDLVALQKKLKATEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNEGKCSELEEELKTVTNNMKSLEAQAEKYSAKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TFB7-1", "uniprot_id": "A0AB32TFB7_DANRE", "id": "A0AB32TFB7-1", "name": "", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEGDKKAAEDRSKQLEDELIQLEKRLRVTEDERDKVLEEYQSVEEKLLTAEEVATKLEDDLLALQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNERCNRRLQDELRVLDQTYKSLKASEEQYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEELDHALNDMTSM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P58771-1", "uniprot_id": "TPM1_MOUSE", "id": "P58771-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK------------------------------------------QLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04692-1", "uniprot_id": "TPM1_RAT", "id": "P04692-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK------------------------------------------QLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09493-1", "uniprot_id": "TPM1_HUMAN", "id": "P09493-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSK------------------------------------------QLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58774-1", "uniprot_id": "TPM2_MOUSE", "id": "P58774-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCK------------------------------------------QLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58775-1", "uniprot_id": "TPM2_RAT", "id": "P58775-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCK------------------------------------------QLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07951-1", "uniprot_id": "TPM2_HUMAN", "id": "P07951-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCK------------------------------------------QLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q650-1", "uniprot_id": "A0A2R8Q650_DANRE", "id": "A0A2R8Q650-1", "name": "", "aln": "------MEAVKKKMMMLKLDKENALDQAEQAETDRKAAEERSK------------------------------------------QHEDELIQMQKKLKGTEDELDKYSEALKDAQEKLEISEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESHVKQMEEELRALDQTLKTLQASEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEEKLRDAKEENIKIHATLDQTLSELNSF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49455-1", "uniprot_id": "TPM4_DROME", "id": "P49455-1", "name": "Tropomyosin-1, isoforms 33/34", "aln": "------MDAIKKKMQAMKVDKDGALERALVCEQEARDANTRAEK------------------------------------------AEEEARQLQKKIQTVENELDQTQEALTLVTGKLEEKNKALQNAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLIVEKERYCMIGDSLDEAFVDLIKGLEPFWNPRNPKPPTPKLPTPTPEELAAMEEARAAAEAAAAAEAEAAEAAAAAGEAGPDGAPAAPGEEKAPAKEPTPPKEPTPPPPPPPPFEYSIDLPPEGAEVPYVKNYEPPPPGSEPEPVPAAEGEAAPAAEGAAPPAEGAAPPAEGAVPPADGAAPPAEGAAPAAEGAAPPADGAAPPAEAAAAPADAAAPAAEAAPAEAPAAEATAAEAPPAEAAPAEAAPAAAEGEAPPA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:*:*: :: : : * ::* :*:::. . .: **.:.*:*******:**:*:*::*:*.:* :*.**.:*******. *::*.** ***:*: * *****:.:::::*:**:******.::*.:*:*:***** * :::::: : :. * *.. :: . :*:.*:::** * :*****:*******:* **:* :* **:.: * . **.:: :: ", "identical_positions": 94, "similar_positions": 91, "identity": "16.61%" }, { "cls_id": "homologset.agr.FB:FBgn0003731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZB0-1", "uniprot_id": "A0ABK0LZB0_RAT", "id": "A0ABK0LZB0-1", "name": "Receptor protein-tyrosine kinase", "aln": "----------------------------------------------------------MGAAAQWFALPSSPSHLCAWISLPCCLSLGCCLA--------VCQGTSNRLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALY-----ENTYALAVLSN-----------YGTNKTGLRELPMRNLQEILIGAVRFSNNPILCNMETIQWRDIVQDVFLSNMSMDVQRHLTGCPKCDPSCPNGSCWGRGEENCQKLTKIICAQQCSRR-CRGRSPSDCCHNQCAAGCTGPRESDCLVCHRFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVE-EDGVSKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFK--GDSFT------RTPPLDPRELEILKTVKEITGFLLIQAWPENWTDLHAFENLEIIRGRTKQH------GQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFG------TPNQKTKIMNNRAEK-DCKATNHVCNPLCSSEGCWGPEPTDCVSCQNVSRGRECVDKCNILEGEPREFVE-NSECIQCHPECLPQ-TMNITCTGRGPDNCIKCAHYVDGPHCVKTCP-----------------SGIMGENNTL---------------------------------VWKFADANNV-----------CHLCHANCTYG------------------------------------------------CAGPGLKGCQQ---------------------------------------------------------PEGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGD--ERMHLPSPTDSNFYRALMEEEDMEDVVDADEYLIPQQGFFNS---------------------------------------------------------------PS---TSRTPLLSSLSANSN--SSAVACINRNG--SCRVKEDAF---LQRYSSDPTSVLTEDN----IDDTFLPVP----------------EYINQS-------------------------------VPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVSNP------------------------------------------------------------------------------------------------------------------------------EYLN--TAQPTCLSSGFDSSALWIQKGSHQMSLDNPDYQQDFFPKEA------KPNGIFKG-PTAENAEYLRVAPPSSEFIGA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01279-1", "uniprot_id": "EGFR_MOUSE", "id": "Q01279-1", "name": "Epidermal growth factor receptor", "aln": "------------------------------------------------------------------MRPSGTARTTLLVLLTALCAAGGALEEK-----KVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALY-----ENTYALAILSN-----------YGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHR-CRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVE-EDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFK--GDSFT------RTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQH------GQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFG------TPNQKTKIMNNRAEK-DCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVE-NSECIQCHPECLPQ-AMNITCTGRGPDNCIQCAHYIDGPHCVKTCP-----------------AGIMGENNTL---------------------------------VWKYADANNV-----------CHLCHANCTYG------------------------------------------------CAGPGLQGCEVW--------------------------------------------------------PSGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGD--ERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNS---------------------------------------------------------------PS---TSRTPLLSSLSATSN--NSTVACINRNG--SCRVKEDAF---LQRYSSDPTGAVTEDN----IDDAFLPVP----------------EYVNQS-------------------------------VPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVGNP------------------------------------------------------------------------------------------------------------------------------EYLN--TAQPTCLSSGFNSPALWIQKGSHQMSLDNPDYQQDFFPKET------KPNGIFKG-PTAENAEYLRVAPPSSEFIGA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00533-1", "uniprot_id": "EGFR_HUMAN", "id": "P00533-1", "name": "Epidermal growth factor receptor", "aln": "------------------------------------------------------------------MRPSGTAGAALLALLAALCPASRALEEK-----KVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYY-----ENSYALAVLSN-----------YDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGR-CRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEME-EDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFR--GDSFT------HTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQH------GQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFG------TSGQKTKIISNRGEN-SCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVE-NSECIQCHPECLPQ-AMNITCTGRGPDNCIQCAHYIDGPHCVKTCP-----------------AGVMGENNTL---------------------------------VWKYADAGHV-----------CHLCHPNCTYG------------------------------------------------CTGPGLEGCPT----------------------------------------------------------NGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGD--ERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSS---------------------------------------------------------------PS---TSRTPLLSSLSATSN--NSTVACIDRNGLQSCPIKEDSF---LQRYSSDPTGALTEDS----IDDTFLPVP----------------EYINQS-------------------------------VPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNP------------------------------------------------------------------------------------------------------------------------------EYLN--TVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEA------KPNGIFKG-STAENAEYLRVAPQSSEFIGA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06494-1", "uniprot_id": "ERBB2_RAT", "id": "P06494-1", "name": "Receptor tyrosine-protein kinase erbB-2", "aln": "---------------------------------------------------------------------MELAAWCRWGFLLALLPPGIAGT-------QVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYVPA-NASLSFLQDIQEVQGYMLIAHNQVKRVPLQRLRIVRGTQLF-----EDKYALAVLDNRDPQDNVAASTPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVFRKNNQLAPVDIDTNRSRACPPCAPACKDNHCWGESPEDCQILTGTICTSGCAR--CKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMHNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLRGARAITSDNVQEFDGCKKIFGSLAFLPESFD--GDPSS------GIAPLRPEQLQVFETLEEITGYLYISAWPDSLRDLSVFQNLRIIRGRILHD------GAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNAHLCFVHTVPWDQLFR------NPHQALLHSGNRPEEDLCVSSGLVCNSLCAHGHCWGPGPTQCVNCSHFLRGQECVEECRVWKGLPREYVS-DKRCLPCHPECQPQ-NSSETCFGSEADQCAACAHYKDSSSCVARCP-----------------SGVKPDLSYM--------------------------------PIWKYPDEEGI-----------CQPCPINCTHS------------------------------------------------CVDLDERGCPAE--------------------------------------------------------QRASPVTFIIATVVGVLLFLILVVVVGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ-N--EDLGPSSPMDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFSPDPTPGTGSTAH--------------------------------RRHRSSSTRSGGGELTLGLEPSEEGPPRSPLAPSEGAGSDVFDGDLAMGVTKGLQSLSPHDLSP---LQRYSEDPTLPLPPETDGYVAPLACSPQP----------------EYVNQSE------------------------------VQPQPPLTPEGPLPPVRPAGATLERPKTLSPGKNGVVKDV------------------------------------------------------------------------------------------------------------------------------FAFGGAVENPEYLVPREGTASPPHPSPAFSPAFDNLYYWDQNSSEQG------PPPSNFEGTPTAENPEYLGLDVPV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70424-1", "uniprot_id": "ERBB2_MOUSE", "id": "P70424-1", "name": "Receptor tyrosine-protein kinase erbB-2", "aln": "---------------------------------------------------------------------MELAAWCRWGFLLALLSPGAAGT-------QVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPA-NASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLF-----EDKYALAVLDNRDPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQLAPVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCAR--CKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAGVCYGLGMEHLRGARAITSDNIQEFAGCKKIFGSLAFLPESFD--GNPSS------GVAPLKPEHLQVFETLEEITGYLYISAWPESFQDLSVFQNLRVIRGRILHD------GAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVNTVPWDQLFR------NPHQALLHSGNRPEE-ACGLEGLVCNSLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVWKGLPREYVR-GKHCLPCHPECQPQ-NSSETCYGSEADQCEACAHYKDSSSCVARCP-----------------SGVKPDLSYM--------------------------------PIWKYPDEEGI-----------CQPCPINCTHS------------------------------------------------CVDLDERGCPAE--------------------------------------------------------QRASPVTFIIATVVGVLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ-N--EDLGPSSPMDSTFYRSLLEDDDMGELVDAEEYLVPQQGFFSPDPALGTGSTAH--------------------------------RRHRSSSARSGGGELTLGLEPSEEEPPRSPLAPSEGAGSDVFDGDLAVGVTKGLQSLSPHDLSP---LQRYSEDPTLPLPPETDGYVAPLACSPQP----------------EYVNQPE------------------------------VRPQSPLTPEGPPPPIRPAGATLERPKTLSPGKNGVVKDV------------------------------------------------------------------------------------------------------------------------------FAFGGAVENPEYLAPRAGTASQPHPSPAFSPAFDNLYYWDQNSSEQG------PPPSTFEGTPTAENPEYLGLDVPV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04626-1", "uniprot_id": "ERBB2_HUMAN", "id": "P04626-1", "name": "Receptor tyrosine-protein kinase erbB-2", "aln": "---------------------------------------------------------------------MELAALCRWGLLLALLPPGAAST-------QVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPT-NASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLF-----EDNYALAVLDNGDPLNNTTPVT-GASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCAR--CKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFD--GDPAS------NTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHN------GAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFR------NPHQALLHTANRPED-ECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVN-ARHCLPCHPECQPQ-NGSVTCFGPEADQCVACAHYKDPPFCVARCP-----------------SGVKPDLSYM--------------------------------PIWKFPDEEGA-----------CQPCPINCTHS------------------------------------------------CVDLDDKGCPAE--------------------------------------------------------QRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ-N--EDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVH--------------------------------HRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSP---LQRYSEDPTVPLPSETDGYVAPLTCSPQP----------------EYVNQPD------------------------------VRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDV------------------------------------------------------------------------------------------------------------------------------FAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERG------APPSTFKGTPTAENPEYLGLDVPV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62956-1", "uniprot_id": "ERBB4_RAT", "id": "Q62956-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "-------------------------------------------------------------------MKLATGLWVWGSLLVAARTVQPSASQS------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLY-----EDRYALAIFLN----------YRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTIGSSGCGRCHKSCT-GRCWGPTENHCQTLTRTVCAEQCDGR-CYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSS-SCVRACPSSKMEVE-ENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIH--GDPYN------AIDAIDPEKLNVFRTVREITGFLNIQTWPPNMTDFSVFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFS------TVNQRIVIRDNRRAE-NCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFEN-GSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DVLQG-ANS---------------------------------FIFKYADQDRE-----------CHPCHPNCTQG------------------------------------------------CNGPTSHDCIYYP------------------------------------------------WTGHSTLPQHARTPLIAAGVIGGLFILVIMALTFAVYVRRKSIKKKRALRRFLET-ELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGD--DRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDS---------------NRSEIGHSPPPAYTPMSGSQFVYQDGGFATQQGMPMPYTATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVVPH-VQEDS--STQRYSADPTVFAPERNPRAELDEEGYMTPMHDKPKQE------YLNPVEENPFVSRRKNGDLQALDN-----PEYHSASSGPPKA-EDEYVNEPLYLNTFTNALG-NAEYMKNSLLSVP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRP-----IVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61527-1", "uniprot_id": "ERBB4_MOUSE", "id": "Q61527-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "-------------------------------------------------------------------MKLATGLWVWGSLLMAAGTVQPSASQS------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLY-----EDRYALAIFLN----------YRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSGCGRCHKSCT-GRCWGPTENHCQTLTRTVCAEQCDGR-CYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSS-SCVRACPSSKMEVE-ENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIH--GDPYN------AIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFS------TINQRIVIRDNRRAE-NCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFEN-GSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG-ANS---------------------------------FIFKYADQDRE-----------CHPCHPNCTQG------------------------------------------------CNGPTSHDCIYYP------------------------------------------------WTGHSTLPQHARTPLIAAGVIGGLFILVIMALTFAVYVRRKSIKKKRALRRFLET-ELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGD--DRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDS---------------NRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPH-VQEDS--STQRYSADPTVFAPERNPRGELDEEGYMTPMHDKPKQE------YLNPVEENPFVSRRKNGDLQALDN-----PEYHSASSGPPKA-EDEYVNEPLYLNTFANALG-SAEYMKNSVLSVP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRP-----IVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15303-1", "uniprot_id": "ERBB4_HUMAN", "id": "Q15303-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "-------------------------------------------------------------------MKPATGLWVWVSLLVAAGTVQPSDSQS------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLY-----EDRYALAIFLN----------YRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCT-GRCWGPTENHCQTLTRTVCAEQCDGR-CYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSS-SCVRACPSSKMEVE-ENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIH--GDPYN------AIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFS------TINQRIVIRDNRKAE-NCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFEN-GSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG-ANS---------------------------------FIFKYADPDRE-----------CHPCHPNCTQG------------------------------------------------CNGPTSHDCIYYP------------------------------------------------WTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLET-ELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGD--DRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDS---------------NRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPH-VQEDS--STQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQE------YLNPVEENPFVSRRKNGDLQALDN-----PEYHNASNGPPKA-EDEYVNEPLYLNTFANTLG-KAEYLKNNILSMP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRP-----IVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZ77-1", "uniprot_id": "A0A8N7UZ77_DANRE", "id": "A0A8N7UZ77-1", "name": "Receptor protein-tyrosine kinase", "aln": "-------------------------------------------------------------MDMQPLHTNKMRSDILIALFLTAVIVPLCTSQS------VCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLY-----EGRYSLAIFLN----------YRRDGYFGLRQLGLKNLTEILNGGVYVDQNKFLCHADTIHWHDIIKNPRSELLVVPSNNSGNTCRRCHRSCN-GRCWGHQEDQCQSLTKTVCAEQCDGR-CFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHS-SCVRACPSNKMEVE-ENQTKMCIPCTDICPKVCDGIGTGSLQMAQTVDSSNIEKFVNCTKINGNLIFLITGIK--GDMFH------GIRALDPDRLNVFRTVREITGFLNVQSWPENMTDLGVFSNLATIGGRSLYS------GISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFR------TSTQRALIKNNREPR-ECSKEQKICDPLCSEAGCWGPGPDQCLSCKYFSRGKTCVKSCNLYYGDVREFAN-GSVCVECDSQCEKAGEKGLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG-ANS---------------------------------FIFKYAETNNE-----------CHPCHPNCTQG------------------------------------------------CTGPRIQDCVG----------------------------------------------------------ILDRTPLIAAGLIGGLFVIVIIALGVAVYIRRKSIKKKRALRRFLET-ELVEPLTPSGAAPNQAQLRILKETELKRVKILGAGAFGMVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLDTDEKEYNSDGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTRDIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGD--DRMKLPSPNHSTFFKSLLDEEELDDLMDADEYLVPQTCNISTSTYTSRTTMDA---------------SWT-LRCRD---------RVFSPEDGMGACSRDVPASASAVFVPV----STQAAGLNVLEEQHCNGSLKKQQPMSGSGDDC--DGQRYSADPTVFLGERSLKN-TDEDGYMSPMN-KSTSD------HLSPVEENPFVNHRKNGNITALDN-----PGYHSTPDKKSKAEEDEYINEPLYLNAYNTTGGTNLEIMRRNGSSIPLQMTTATSAASSHIILSTQPGKAHHHGQGTHVHFAIPPVQPPQTRAMSQNGQHSQSSHAVESNSSSMSANPSLLSQISLVSQQIQPCLASQSQVPKSTVPNKSISGLPGHLVYPVNMLQTGHTGTVMADRKSKKNFDNPDYWQHSLPPKVTQANPQDPTQTCKSKHLYRHSIRSRL-----AVADNPEFVSEFNKRPGPVLPPPPYRHRNTVV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q7Y5-1", "uniprot_id": "A0A8M9Q7Y5_DANRE", "id": "A0A8M9Q7Y5-1", "name": "Receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------------------MWPVRFLLLFCLVFTFAVLQRSSGQS------VCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLY-----EGRYSLAIFLN----------YRRDGYFGLRQLGLRNLTEILNGGVYVDQNKFLCHADTIHWQDIIKNPRSELLVVPSNNSGNTCRRCHRSCN-GRCWGPQEDQCQSLTKTVCAEQCDGR-CFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHS-SCVRACPSNKTEVE-ENNIKMCIQCTEICPKMCDGIGTGSLQSAQTVDSSNIEKFVNCTKINGNLIFLITGIK--GDMYH------GIRALDPERLNVFRTVREITGYLNIQSWPENMTDLSVFSNLVTIGGRTLYS------GISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFR------TSTQKAKIKDNRDPR-ECSQQRMVCDPLCSVSGCWGPGPNQCLSCKYFSRGRTCVRSCNLYNGDVREFAN-GSTCVECDSQCEKAEDKSLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG-ANS---------------------------------FIFKYPETNNE-----------CHPCHPNCTQG------------------------------------------------CTGPRIQDCIG----------------------------------------------------------ILDRTPLIAAGVIGGMFVVVIVALGFAIFFRRKSIKKKRALRRFLET-ELVEPLTPSGTAPNQAQLRILKETELKRVKILGTGAFGTVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLETNEKEYSADEGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGD--DRMKLPSPNHSKFFQSLLDEEELDDLMDADEYLVPHSLNAPPTSHIPHPHVDS---------------NQNQFGYHD---------GSRCPEDVT--RFHEVAAAGNAPSALG----SAQRAGLDLVEEQHCNGSLKKQATVH-SVEDS--SGQRYSADPTVLLGEKTQREDTDEDGYMSPMKDKISTN------HLNPVEENPFVTRRKSKDVHALDN-----PGYHNTPDGKPKC-EDEYINEPLYLNTFNNTSDIHQEMLRKNGVSIPAQMTTAG-----HILQT---GKPHHHSHGPHVHFAIPPVQPVHPGPMSQNDHN---AHSVQSGHDHAVKSGPSAGQICLVSHQVQQGHPSKSNRSPQQFQLSGGK-LPGHPVQPG-----SQIGTVLVDKMYKNSFDNPEYWQHSLPP--PQISQDSSSAVCNNKFLYKQNGRVQP-----PAAENPEYLSGVK--PGMVLPPPPYRQRNTVV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62799-1", "uniprot_id": "ERBB3_RAT", "id": "Q62799-1", "name": "Receptor tyrosine-protein kinase erbB-3", "aln": "-------------------------------------------------------------------MRATGTLQVLCFLLSLARGSEMGNSQA------VCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGH-NADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLN----------YNTNSSHALRQLKFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRVRGAEIVVK---NNGANCPPCHEVCK-GRCWGPGPDDCQILTKTICAPQCNGR-CFGPNPNQCCHDECAGGCSGPQDTDCFACRRFNDSGACVPRCPEPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQT-FCVRACPPDKMEVD-KHGLKMCEPCGGLCPKACEGTGSGS--RYQTVDSSNIDGFVNCTKILGNLDFLITGLN--VDPWH------KIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYN-----RGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLR-----GPSEERLDIKYDRPLG-ECLAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNFLQGEPREFVH-EAQCFSCHPECLPM-EGTSTCNGSGSDACARCAHFRDGPHCVNSCP-----------------HGILG-AKG---------------------------------PIYKYPDAQNE-----------CRPCHENCTQG------------------------------------------------CNGPELQDCLG-----------------------------------------------------QAEVLMSKPHLVIAVT--VGLAVILMILGGSFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKA-NKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRA-SGPGTPPAAEPSVLTTKELQEAELEPELDLDLDLEAEEEGLATS-LGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSSLGEACLDSAVLGGREQFSRPISLHPIPRGRPASESSEGHVTGSEAELQEKVSVCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLE-EEDGNGYVMP------------DTHLRGASSS------------------------------REGTLSSVGLSSVLG-TEEEDEDEEYEYMNRKRRGSPPRPPRPG--------------------------------------------------------SLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDED-----YEYMNRRR----------GAGGAGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVRYAR---------LKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61526-1", "uniprot_id": "ERBB3_MOUSE", "id": "Q61526-1", "name": "Receptor tyrosine-protein kinase erbB-3", "aln": "-------------------------------------------------------------------MSAIGTLQVLGFLLSLARGSEMGNSQA------VCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGH-NADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVY-----DGKFAIFVMLN----------YNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVK---NNGGNCPPCHEVCK-GRCWGPGPEDCQILTKTICAPQCNGR-CFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQT-FCVRACPADKMEVD-KNGLKMCEPCRGLCPKACEGTGSGS--RYQTVDSSNIDGFVNCTKILGNLDFLITGLN--GDPWH------KIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYN-----RGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLR-----GPAEERLDIKYNRPLG-ECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVH-EAHCFSCHPECQPM-EGTSTCNGSGSDACARCAHFRDGPHCVNSCP-----------------HGILG-AKG---------------------------------PIYKYPDAQNE-----------CRPCHENCTQG------------------------------------------------CKGPELQDCLG-----------------------------------------------------QAEVLMSKPHLVIAVT--VGLTVIFLILGGSFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKA-NKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRA-SGPGIPPAAEPSALSTKELQDAELEPDLDLDLDVEVEEEGLATT-LGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSNLGEACLDSAVLGGREQFSRPISLHPIPRGRQTSESSEGHVTGSEAELQERVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLE-EEDGNGYVMP------------DTHLRGTSSS------------------------------REGTLSSVGLSSVLG-TEEEDEDEEYEYMNRKRRGSPARPPRPG--------------------------------------------------------SLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDED-----YEYMNRRR----------GAGGSGGDYAAMGACPAAEQGYEEMRAFQGPGHQAPHVRYAR---------LKTLRSLEATDSAFDNPDYWHSRLFPKANAQRI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21860-1", "uniprot_id": "ERBB3_HUMAN", "id": "P21860-1", "name": "Receptor tyrosine-protein kinase erbB-3", "aln": "-------------------------------------------------------------------MRANDALQVLGLLFSLARGSEVGNSQA------VCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGH-NADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVY-----DGKFAIFVMLN----------YNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVK---DNGRSCPPCHEVCK-GRCWGPGSEDCQTLTKTICAPQCNGH-CFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQT-SCVRACPPDKMEVD-KNGLKMCEPCGGLCPKACEGTGSGS--RFQTVDSSNIDGFVNCTKILGNLDFLITGLN--GDPWH------KIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYN-----RGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLR-----GPTEERLDIKHNRPRR-DCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAH-EAECFSCHPECQPM-EGTATCNGSGSDTCAQCAHFRDGPHCVSSCP-----------------HGVLG-AKG---------------------------------PIYKYPDVQNE-----------CRPCHENCTQG------------------------------------------------CKGPELQDCLG-----------------------------------------------------QTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKA-NKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRE-SGPGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDNLATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGESCQESAVSGSSERCPRPVSLHPMPRGCLASESSEGHVTGSEAELQEKVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLE-EEDVNGYVMP------------DTHLKGTPSS------------------------------REGTLSSVGLSSVLG-TEEEDEDEEYEYMNRRRRHSPPHPPRPS--------------------------------------------------------SLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIMPTAGTTPDED-----YEYMNRQR----------DGGGPGGDYAAMGACPASEQGYEEMRAFQGPGHQAPHVHYAR---------LKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD22-1", "uniprot_id": "A0A8M2BD22_DANRE", "id": "A0A8M2BD22-1", "name": "Receptor protein-tyrosine kinase", "aln": "----------------------------------------------------------------MKIMKMKSAMLQMIAMCLALRSPARAQTQEGKPEVGVCTGTQNLLSVTGSSEVQYKLMKEMYTGCQIVIGNLEITQMEH-NRDFSFLQSIREVTGYILIAINQFRRLPLEQLRVIRGTSLY-----EDKFALAVLVN----------YQKDGVYGLRELGLTHLTEILEGGVQIIQNKFLSYAPQINWQDIVKNSGAEVIIQ---DNGPEVP-CHESCG-GPCWGPGNDTCQILTKTVCALQCNVR-CFGRSPSECCHNECAGGCTGPLDTDCFACRNFNNSGSCVSQCPRADIYNKVTFKMEPNPNAKYQFGSMCVSHCPPNFVVDGS-SCVSSCPADKMEVD-KTGVKRCEKCEGLCPKACVGTGTGTA-SRQTVDSQNIDSFINCTKIQGSLHFLVTGIK--GDSYN------NISALDPKKLKIFNTVREITDILSIQSWPEELEDLSVFSNLATIQGRTLYRGVSSKRGYSLLVMKIPTLKSLGLRSLKRISDGGIYITGNTQLCYHHTVNWTRLFGSGPRALRRQKSLDIKENRPQE-QCKLEGHVCDPLCSSEGCWGPGPDQCLSCKNFRRGGTCVPDCNFMSGEQREFAGPKNECMACHQECALQ-DSGDTCKGPGSDECKACAHLQDGPYCVSSCP-----------------EGVQG-ENGL--------------------------------IIYKFPNRQNK-----------CQPCHANCTLG------------------------------------------------CLGPGQNDCVD-----------------------------------------------------SSRSSAGLPVTAIVLSVIFCVLLAFSVFVLSVLYRRSLSIRRKRAMRRYLQSGESFEPLEPGEKG-VKVHARILRTSELKKIKLLGSGVFGTVHKGIWIPEGDTVKIPVAIKTIQDRTGRQTFQEITDHMLAMGSLDHAYIVRILGICPGASLQLVTQLSPQGSLLDHIRQRRDNLNPQRLLNWCVQIAKGMYYLEEQRMVHRNLAARNILLKSDLIVQIADYGIADLLYPDEKKYFFNEIKTPIKWMALESILFRRYTHQSDVWSYGVTVWEMMSYGAEPYSAMRPQDVPDLLEKGERLSQPQICTIDVYMVMVKCWMIDENVRPTFKELANEFTRMARDPHRYLVIKEEDRAPDSASDETHQNGTEIDILGVALEDQDDEVLEDAIDAP-RYITPSRSFSRLRIDSHR----SSLTPSTTAGYLPMTPG------LESSVQTGWASRSR------LDSACTVSESSEGRG-ALELEMNDDFSSVGSLRRVRH---REDSAYMSQRDSLSGPPETTSTGTQG-EEDQNEYVLPGFGESPEKETLLFTSSRSTLSQKRLSRGHSGDFLEANR-----GAGEEYEYMNNQTLSLSHIPGQLKEYNQRAPRNRSASFNPGGMYSNHKPSRPS----------------KRSSIEGSESSGGLSQSST--DQRSHSDGDFLSSEAEYTDGDLEVEYEYMDIRGAGGPAANMLLKLHLPRPVSNPPLRRSPEDDDEDEDYQYSNHQPRLRNSLRVQGGGGE-AYEYEDMDSLAAGGASGAEYQN--LDGEDEERDEDWSGGPRSPGPYVQVHAGTN--HNAFDNPDYWHSRSFHKTKAVRT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N4R3-1", "uniprot_id": "A0A8M1N4R3_DANRE", "id": "A0A8M1N4R3-1", "name": "Receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------------------MGQQVLALCALLFLCVPQPVTSQTQE------VCTGTKNALSSTGTPEQHYNNLKERYTGCEIVMGNLEITQMEN-DLDFSFLGSIREVTGYILIAMNQFRKLPLNQLRVIRGSSLY-----DKEWALSVFHN----------FDTH--TGLEDLGLTNLTEILEGGVQIVHNRNLSYAPLINWQDIVRDGDARIQIQ---DNGGRGS-CNPACG-EFCWGPSNDQCQKLTKTVCALQCLGH-CFGTNPNECCHPECAGGCTGPRDTDCFACRHVNYSGSCVPHCPWPVVYNQQTFQVEPNADAMYQFGSICVPKCPGHFVVDGS-ACVSSCPPGKTEIE-KNQIKQCETCIGLCPKVCEGTGAN---HRQTVDSSNIDSFINCTKIQGSLHFLILGIK--GDVYN------NIPPLEPEKLKVFNTVREITGILNIQSWPDELHDLSVFSSLTTIQGRSLYN---PKRPFSLLVMKIPSLTSLGLRSLREISDGSVYITQNMNLCYHHTINWTQIF---PRNQLQRRRNDIKENKQKI-QCEEEGHVCDPLCSDAGCWGPGPEQCLSCRNYSRLGTCVSHCNLYSGEPREFAASNKECLACHSECLLQ-NGKQTCLGKGADQCVACSNLMDGPHCVSSCP-----------------NGVNG-EKGQ--------------------------------TIFKYSTAAGH-----------CELCHFNCTRG------------------------------------------------CTGPALRDCVD-----------------------------------------------------PDRNVNSSQIAGIAVAVFAGITVLLALFVLGMLYHRGLAIRRKRALRRYLESGESMEPLDPGEKG-TKVHARILKPQELRKGKLLGYGVFGTVNKGFWIPEGDSLKIPVAIKTIQNRSSRQTFTEITDHMLSMGSLDHPYIVRLIGICPGASLQLITQLSPHGSLLQHLRQHKDSLDPQRLLNWCVQIAKGMYYLEEHCMAHRNLAARNILLKSDYIVQISDFGVADLLYPDDKKYVYSEHKTPIKWMALESILFGRYTHQSDVWSYGVTVWEMMSYGAEPYASMHPHDVPGLLEKGERLAQPQICTIDVYMVMVKCWMIDENVRPTFKELASEFTRMARDPPRYLVVRPAQNGSGAEESQRYVKSSHLEVGLEEEDDDEDEGLQVGFATPPLQLSPTRSHSRVRIASYK----STSEHTAPIGYLPMTPG------PGDEPRQLRAQRRK------IGSVRTESECSEGRGTIVDIEAIEITSQTGSLRRGRS---RMDSAYISGGVSVASDP--FSPGLEGVDEDHYGYVLP-TERDFRSAVPHGRTSRNSKSTPKTDATQEYELMNKQTNKLSSSPTDSTDHLKPASLVSAHICSSLPQKKEMDSAQTQDEILPQKRETDSIQSQENN-------------LPQKSETDSTQTQESEKDASFQPDNLESAENCLIGSETLNDGGQSEDEEQLPRLAMVEYEYMDIRTDEHQQN-VAGKRTTNGPNEVEREAIYQNISQPLRFHENPDSAGNTMQRRGEYVDMEASGRSGCEVGDYQNVPVKGRPVVGEESQNTGLRS---YIKVCAGVEPQNTSFDNPDYWHSRLFHKQDTVCT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYS-----------------KMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCT-HGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNG-ACVRSCPQDKMDKG-----GECVPCNGPCPKTCP--------GVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMES-----MFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQK------EPEQKVWVNENLRAD-LCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYISN---AYKFDNRTCKICHPECRTC-------NGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGD-----KFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQP---------------------------------------------------------------------------KAAPGPSHRTDCTDEMPKLNRYCKDPSNKNSSTGDDERDSSAREVGVGNLRLDLPVDEDDYLMP------------------------------------------------------TCQPGPNNNNNMNNPNQNNMAAVGVAAGYMDLIG-------------------------------------------------------------------------------------------------------------------------------------VPVSVDNPEYLLNAQTLGVGESPIPTQTIGIPVMGGPGTMEVKVP-----MPGSEPTSSDHEYYNDTQRELQPLHRNRNTETRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ** * . : : : : * * ***::. : .:*** ::** **:*:: . : : .*:::** : : ::: : . : * : * ::* * * . * *. : * ::. * * *** . ** :: *: * * * :*** **.** ** ..**:.* .. .. . ** ** *: * . * :*. ** ** : : *. * : * * * * : : *:. * *. * *.: :* : : .: * . .:: *:.***. * :. :: * .* * ** * : : * ::.*:.:. * : * .**: .: * : . : * * * ***. . :*:.* *: * . : * *. :* * .* * * : * ** ** . .::: *. * * * . .* : . . : .. : *. * *** *. **.: *::: :** *.** * **.*:*:*:.:****.** : . :. :: . . :.. : :::.:* . : *:** * *.**:::::.: :..: **** ****** ***: :.**:** **::::: ::::*:*:* ** :..: * ****:***.* :* :****::***:**::::* .*: : ::..::* * :* ** **::*:* ::.** :* ** *::* *:.:**** *::.: * . . * ", "identical_positions": 224, "similar_positions": 238, "identity": "12.79%" }, { "cls_id": "homologset.agr.FB:FBgn0003742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXL0-1", "uniprot_id": "A0A8I5ZXL0_RAT", "id": "A0A8I5ZXL0-1", "name": "Transformer-2 protein homolog alpha", "aln": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSR-VSKHSESHSRSRSKSRSRSRRHSHRRYTRSR--SHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTH--GGGGGGGGGGGGGGGGGGRRRDSYYDRGYDRG------YDRYEDYDYRY-RRSPSP-YYSR--YRSRSRSRSYSPR----RY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFR5-1", "uniprot_id": "TRA2A_MOUSE", "id": "Q6PFR5-1", "name": "Transformer-2 protein homolog alpha", "aln": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSR-VSKHSESHSRSRSKSRSRSRRHSHRRYTRSR--SHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGGGGRRRDSYYDRGYDRG------YDRYEDYDYR--RRSPSP-YYSR--YRSRSRSRSYSPR----RY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13595-1", "uniprot_id": "TRA2A_HUMAN", "id": "Q13595-1", "name": "Transformer-2 protein homolog alpha", "aln": "MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSR-VSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTH---SGGGGGGGGGGGGGGGGRRRDSYYDRGYDRG------YDRYEDYDYRYRRRSPSP-YYSR--YRSRSRSRSYSPR----RY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62997-1", "uniprot_id": "TRA2B_RAT", "id": "P62997-1", "name": "Transformer-2 protein homolog beta", "aln": "MSDSGEQNYGERESRSASRSGS-AHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRR-SRSRSYSRDYRRRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTY---GSSRRRDYYDRGYDRGYDDRD-YYSRSYRGGGGGGGGWRAAQDRDQIYRRRSPSP-YYSRGGYRSRSRSRSYSPR----RY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62996-1", "uniprot_id": "TRA2B_MOUSE", "id": "P62996-1", "name": "Transformer-2 protein homolog beta", "aln": "MSDSGEQNYGERESRSASRSGS-AHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRR-SRSRSYSRDYRRRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTY---GSSRRRDYYDRGYDRGYDDRD-YYSRSYRGGGGGGGGWRAAQDRDQIYRRRSPSP-YYSRGGYRSRSRSRSYSPR----RY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62995-1", "uniprot_id": "TRA2B_HUMAN", "id": "P62995-1", "name": "Transformer-2 protein homolog beta", "aln": "MSDSGEQNYGERESRSASRSGS-AHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRR-SRSRSYSRDYRRRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTY---GSSRRRDYYDRGYDRGYDDRD-YYSRSYRGGGGGGGGWRAAQDRDQIYRRRSPSP-YYSRGGYRSRSRSRSYSPR----RY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19018-1", "uniprot_id": "TRA2_DROME", "id": "P19018-1", "name": "Transformer-2 sex-determining protein", "aln": "---------MDREPLSSGRLHC--SARYKHKRSASSSSAGTTSSGHKDRRSDYDYCGSRRHQRSSSRRRSRSR---------SSSESPPPEPRHRSGRSSR---DRERMHKSREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPR----GKAPRSFSPRRGRRVYHDRSASPYDNYRDR------YDYRNDRYDRNLRRSPSRNRYTR--NRSYSRSRSPQLRRTSSRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. * .: . * : : * . * :. :* . * :* * *: :*** * *.* . : *:* .:* *.* .* :*:.. *:*****. *:::.:**:*.:***: :.:* * :: *****.*:***.:.*:: * : ..*:*:********:***:*.******:*:** . . . *. .* : :* ***** *:* ** ***** . * **", "identical_positions": 93, "similar_positions": 68, "identity": "31.1%" }, { "cls_id": "homologset.agr.FB:FBgn0003744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VJ4-1", "uniprot_id": "STK38_MOUSE", "id": "Q91VJ4-1", "name": "Serine/threonine-protein kinase 38", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTG-STPCSSMSN------------------HTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------LPSDFT------------------FQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFCCEWEHRIGAP-GVEEIKNNLFFEGVDWEHIRERPAAISIEIKSIDDT-----SNFDEFPES-DILKPT---VTTSSHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKQ3-1", "uniprot_id": "A0A8I6GKQ3_RAT", "id": "A0A8I6GKQ3-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------------------------------------------MWAGRRRARAVPLPGKRRRRVAHAQCRPQRPLSPQSEGVTGEPWPLRAAVFSGSWGSSCCPLPSRLGSRAPSASPARRGRSRAARSSRLCRLCRRRPRASLPPGSVFSGSFSLCSPG---------------------------------CPGCPGTPPPGLVELFAMAMTG-STPCSSMSN------------------HTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVRMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------LPSDFT------------------FQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFCCEWEHRIGAP-GVEEIKSNPFFEGVDWEHIRERPAAISIEIKSIDDT-----SNFDEFPES-DILKPT---VTTSNHPETDYKSKDWVFINYTYKRFEGLTARGAIPSYMKAAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15208-1", "uniprot_id": "STK38_HUMAN", "id": "Q15208-1", "name": "Serine/threonine-protein kinase 38", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTG-STPCSSMSN------------------HTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------LPSDFT------------------FQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAP-GVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDT-----SNFDEFPES-DILKPT---VATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGE2-1", "uniprot_id": "A0AB32TGE2_DANRE", "id": "A0AB32TGE2-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATRG-HASSSLMSN------------------HTKERVTMAKVTLENFYSNLITQHEEREMRQQKLEKVMDEEGLPDEEKRVRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLQKEQVAHIRAERDILVQADSLWVVKMFYSFQDKLNLYLLMEFLPGGDMMTLLMKKDTLTEEETQFYVAETVLAIDFIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHS--------QSNDLT------------------FQHMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMGWKETLVFPPEVPISERAKELILRFCCEADHRIGAG-GVDDIKRNAFFEGVDYDHIRERPAAITIEIKSIDDT-----SNFDEFPDS-DILQPTSPVVVSNHHPESDYKNKDWVFINYTYKRFEGLTARGAIPSYMKSGKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TSE6-1", "uniprot_id": "ST38L_MOUSE", "id": "Q7TSE6-1", "name": "Serine/threonine-protein kinase 38-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTAGATTTFPMSN------------------HTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDVKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHN--------PPSDFS------------------FQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRFCTDSENRIGNG-GVEEIKGHPFFEGVDWGHIRERPAAIPIEIRSIDDT-----SNFDDFPES-DILQPV------PNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H1-1", "uniprot_id": "ST38L_HUMAN", "id": "Q9Y2H1-1", "name": "Serine/threonine-protein kinase 38-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMTAGTTTTFPMSN------------------HTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHN--------PPSDFS------------------FQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNS-GVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDT-----SNFDDFPES-DILQPV------PNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NBK5-1", "uniprot_id": "TRC_DROME", "id": "Q9NBK5-1", "name": "Serine/threonine-protein kinase tricornered", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMSSRTQDADGASIRFSD------------------HTLDKATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQA--------KPSDFIG-----------TCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDT-----SNFDEFPDV-SLEIPS------APIPQGGEIAKDWVFINYTYKRFEVRNLE------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53894-1", "uniprot_id": "CBK1_YEAST", "id": "P53894-1", "name": "Serine/threonine-protein kinase CBK1", "aln": "MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQIPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQQEQENVQVQQQLSQAQQQNSRQQQQQLQYQQQQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFDYLTRKNAL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: * ::.: .*:.:**:*.. : **: * :** : ... : .: : .:**:::***:* **.::**.::****:***************::**** * *::* :*:*:.*::****:*. :* *** ::***** ***:********:**:*:: : ::*: *:**::* ***: **:*******:****:*:* :**:*******.**::*:* :::*:.* : .. *..::: ::*::.** :*:************:*: **. *******.**** *:*:*****:.**:**:*:*.:.:** ** :: :* .*: * .: . :.*:* * :::* **.***: **: *. :: ** ** .::::.*: : . :* *:.***.**: . . ", "identical_positions": 190, "similar_positions": 147, "identity": "24.84%" }, { "cls_id": "homologset.agr.FB:FBgn0003748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLT2-1", "uniprot_id": "TREA_MOUSE", "id": "Q9JLT2-1", "name": "Trehalase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MTWELHLLLLLG-------------------LGLRSQEALPPPCESQIYCHGELLHQVQ--MAQLYQDDKQFVDMS-LATSPDEVLQKFS--ELATVH-NHSIPKEQLQEFVQSHFQPVGQE-LQSWTPEDWKDSPQFLQKISDANLRVWAEELHKIWKKLGKKMKAEVLSYPERSSLIYSKH-------------PFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRIYYLQRSQPPLLTLMMDRYVAHTKDVA-------FLQENIGTLASELDFWTVNRTVSVVSGGQSYVLNRYYVP--YGGPRPESYRKDAELANSVP-EGDRETLWAELKAGAESGWDFSSRWLVG--GPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDTE----------ATKYRNLRAQRLAAMEAVLWDEQKGAWFDYDLEKGKKNLEFYPSNLSPLWAGCFSDPS---VADKALKYLEDSK---ILTYQYGIPTSLRNTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKS-AMFEKYDIS----------NGGHPGGGGEYEVQEGFGWTNG---LALMLLDRYGDQLTSG--TQLASLGPHCLVAALLLSLLLQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7Q9-1", "uniprot_id": "G3V7Q9_RAT", "id": "G3V7Q9-1", "name": "Trehalase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MTWELHLLLLLG-------------------LGLSSQEALPPPCESQIYCHGELLHQVQ--MAQLYQDDKQFVDMS-LATSPDEVLQKFS--ELAVAH-NHSIPREELQNFVQSYFQPVGQE-LQPWTPEDWKDSPQFLQKISDSRLRVWAEELHKIWKKLGKKMKAEVLSHPERSSLIYSEH-------------PFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRVYYLQRSHPPLLTLMMERYVAHTNDVA-------FLRENIGTLALELEFWTVNRTVSVGSGGQSYILNRYYVP--YGGPRPESYSKDEELAKTVP-EGDRETLWAELKAGAESGWDFSSRWLVG--GPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDTE----------AKRYRNLRAQRLAAMEAILWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWAGCFSDPS---VADRALKYLEDNK---ILTYQYGIPTSLRNTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKS-AMYEKYDIS----------NGGHPGGGGEYEVQEGFGWTNG---LALMLLDRYGDQLTSG--TQLASLGPHCLVTALLLSLLLQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43280-1", "uniprot_id": "TREA_HUMAN", "id": "O43280-1", "name": "Trehalase", "aln": "----------------------------------------------------------------------------------------------------------------------------------MPGRTWELCLLLLLG-------------------LGLGSQEALPPPCESEIYCHGELLNQVQ--MAKLYQDDKQFVDMP-LSIAPEQVLQTFT--ELSRDH-NHSIPREQLQAFVHEHFQAKGQE-LQPWTPADWKDSPQFLQKISDAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEH-------------PFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTNDTA-------FLQENIETLALELDFWTKNRTVSVSLEGKNYLLNRYYVP--YGGPRPESYSKDVELADTLP-EGDREALWAELKAGAESGWDFSSRWLIG--GPNPNSLSGIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDSQ----------ATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTPLWAGCFSDPG---VADKALKYLEDNR---ILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLAKAPLRRAQEVAFQLAQNWIRTNFDVYSQKS-AMYEKYDVS----------NGGQPGGGGEYEVQEGFGWTNG---VVLMLLDRYGDRLTSG--AKLAFLEPHCLAATLLPSLLLSLLPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PUG5-1", "uniprot_id": "A0A8M1PUG5_DANRE", "id": "A0A8M1PUG5-1", "name": "Trehalase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MHCLIVISST-----------------LLFSSGDALLAPCDSQIYCTGEVLRQVQ--MAKLFDDDKYFVDMT-LTTAPEVVLEAFT--NLSSVFPDKAVPSLELKKFLQTYFKEPGNE-FERWTPTDWHSKPNFLSKVSDSKYRSWAEELHSLWKSLGRKIRDDVRDHPELYSQIYTPH-------------PVVVPGGRFRELYYWDSYWVINGLLLSEMTETARGMILNFVYLVERYGIVPNGGRVYYERRSQPPFLPLMVERFYEATGDKD-------FLRQVLPALEREYSFWMQNRSVDVVTSELTHILNRYNVP--VDHPRPESYSDDVELAEGLS-TEAQKQLWMDLTSGAESGWDFSSRWFIDDTGRNNGSLRDTQTSSILPADLNAIMCRNERLLASFHRSLGNEEK----------ALKYEKALSARIKAVESLLWDAEKGAWFDYNLVNKTRHLSFYPSNLAPLWAQCYSKSE---MSDQAVQYLRDSG---GLDYPNGIPTSLSDSGQQWDMPNTWPPLQHIIIEGLSGLHSAHAQELAFSLAQRWIQTNWRAFIKYE-AMFEKYDVS----------GDGKPGGGGEYEVQLGFGWTNG---VALQLLDQYGDRLSSGGRVPVCSSALIGLVYAVLKSLF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2M2-1", "uniprot_id": "TREA_DROME", "id": "Q9W2M2-1", "name": "Trehalase", "aln": "----------------------------------------------------------------------------------------------------------------------------MFKLPTISLLLVSWSCLVALSQAKTYSLPDLTTD--YNNAIPVDEEEAQDPFASCKIYCEGNLLHTIQTAVPKLFADSKTFVDMK-LNNSPDKTLEDFN--AMMEAK-NQTPSSEDLKQFVDKYFSAPGTE-LEKWTPTDWKENPSFLDLISDPDLKQWGVELNSIWKDLGRKMKDEVSKNPEYYSIIPVPN-------------PVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNGGRVYYHGRSQPPLLTGMVKSYVDFTNDDK-------FAIDALDTLEHEFEFFVNNHNVTVKN----HSLCVYRDS--SSGPRPESYREDVETGEEFPTDEAKELHYSELKAGAESGMDFSSRWFISPTGTNDGNRSALSTTSIVPVDLNAYLYWNAKLIAEFHSKAGNTKK----------VTEYETKAEKLLLGIQEVLWNEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEKISASVMAYIERNK---LDSFPGGVPNTLSYTGEQWDAPNVWAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKTNFAAFSKDR-HMYEKYNAD----------EFGVGGGGGEYEVQTGFGWSNG---VIIEWLSKHGRDISIG-------SGCGCLAGEKRQ---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35172-1", "uniprot_id": "TREB_YEAST", "id": "P35172-1", "name": "Probable trehalase", "aln": "MVDFLPKVTEINPPSEGNDGEDNIKPLSSGSEQRPLKEEGQQGGRRHHRRLSSMHEYFDPFSNAEVYYGPITDPRKQ--SKIHRLNRTRTMSVFNKVSDFKN-GMKDYTLKRRGSEDDSFLSSQGNRRFYIDNVDLALDELLASEDTDKNHQITIEDTGPKVIKVGTANSNGFKHVNVRGTYMLSNLLQELT--IAKSFGRHQIFLDEARINENPVDRLSRLITTQFWTSLTRRVDLYNIAEIARDSKIDTPGAKNPRIYVPYNCPEQYEFYIQASQMNP-SLKLEVEYLPKDITAEYVKSLNDTPGLLALAMEEHVNPSTGERSLVGYPYAVPGGRFNELYGWDSYLMALGLIESNKVDVARGMVEHFIFEIDHYSKILNANRSYYLCRSQPPFLTDMALLVFEKIGGKNNPNAIQLLKRAFRAAIKEYKEVWMSSPRLDSLTGLSCYHSDGIGIPPETEPDHFDTILLPYAEKYNVTLEKLRYLYNEGMIKEPKLDAFFLHDRAVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEKDIAFVIKEYFGNEYKDENDGTVTDSEHWEELAELRKTRINKYMWDEDSGFFFYYNTKLKCRTSYESATTFWSLWAGLATEEQAKITVEKALPQLEMLGGLVACTEKSRGPISIDRPIRQWDYPFGWAPHQILAWKGLSAYG---YQQVATRLAYRWLYMITKSFVDYNGMVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNTSYLLGLKYMNNHARRALAACSPPLPFFNSLKPSEKKLYYL-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32356-1", "uniprot_id": "TREA_YEAST", "id": "P32356-1", "name": "Cytosolic neutral trehalase", "aln": "-------MSQVN-TSQG--------PVAQG----------------RQRRLSSLSEFNDPFSNAEVYYGPPTDPRKQKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDVDKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELT--IAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQASQMHP-SLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISISRPIRQWDYPFGWAPHQILAWEGLRSYG---YLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSSLRPQERNLYGL-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : . . * .::*. : :.: : : *:* : * *. : : : : . :. * : . :.* : .. .* *: ::. : *.: : .: . * : : * ****** *:* **** : **: :: ...:**: :*. :. :. : *..* ** **:**:*. * . : :: .: . : : . : :: .. : .: . * : * : : : . ***: : :: . . :. : :*: : * :: *: .:.: .**. . .: :. * :: . .*** * *.* * : .** :: * .*: : . : ***: * *.. : . **** * : : :. :. . ", "identical_positions": 73, "similar_positions": 143, "identity": "9.17%" }, { "cls_id": "homologset.agr.FB:FBgn0003861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58GIR7-1", "uniprot_id": "A0AC58GIR7_DANRE", "id": "A0AC58GIR7-1", "name": "", "aln": "---MSQQYFRRTENFLYRDRIP-------------LRIVRSESELSPL-EKAYLWAVEKGDYGSVKQALIEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK-KPSGGMQVPPILLDKQFSDFTP--DITPIILAAHTNNYEIIKMLVQKGVSMPQPHQVRCNCMECVSSSDVDSLRHSRSRLNIYRALASPSLVALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSQQCKQFAKDLLDQTRSSRELELILNYKD-----DIN-LLEDEGINDLARLKLAIKYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWASKFMTCIFIGLLFPFFSLFYLIAPKSHYGLFIRKPFIKFICHTASYLTFLFLLLLASQHVNRNLLDQDEN-----SDCKNENLRQNLAPTTVEWMILPWVLGFVWAEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVALSKYN----------NQCRDEWDMWHPALVGEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YESDGKTSNNVTCKGIRCSEQ------NNAFTTMFETLQSLFWSIFGLVA--LHVTNVDAKHDFTEFVGATMFGTYSIISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNVVPSPKSAWYLIRWIKTHCFKIKQR------KRTETLGSLGVRGHFLLMLYSFIFHYMLTNFLFTEYYIYINNAFGFHYHIIKQSVLK-KAIQLFSFVQIRAAENVRTNRQYQEVLRNLVKRYVAARIRDAKKEEG-----------------------------------------------------------LTEDNFKELKQDISSFRYEVMGMMKGTKTGMSTSKGNTAESSLVYPENALKCNSTSTGSTLKGKMRLQS---------------------ITNTMIQEGGP--------------KAWKPTG---CSNLADSSVPNKNISHQLN--------------------CKGPN---------NPGEMYSVSEEAGESESE---EQGDGKQ------AENLDCK---------------------KKKNQNKETEKDGV----------NNDVEEDEELTYMRYMCEEEMNEGNEGETSRL----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IM91-1", "uniprot_id": "A0A0R4IM91_DANRE", "id": "A0A0R4IM91-1", "name": "", "aln": "---MSQLYFRRTDNSSYRDRIP-------------LRIVRAESELSTQ-EKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK-KPSGEKQVPPILLDKQFSDFTP--DITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRD-----DMN-LLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSNNPD-----------------RQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSG---------CKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEN----SEGMTCKGIRCERQ------NNAFSTLFETLQSLFWSIFGLIS--LYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVFKRRS-------KRKETFGTLGRR----------------------------------------------------------AAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEG-----------------------------------------------------------LTEENFKELKQDISSFRYEVIGMMKGNRKSTRANKSDTSASDVSHPEGSLQYSSALK---QNSKLHLYD---------------------VTTALQQQNSE--------------EAKASLG---CLANGSAVVLTEPILKDKARSDFPKD-------FTDFGLFPKKQ---------NPNKIYSLAEEATESDPD---ILDWGKE------DKPLAGK---------------------VEQDVNESKCLMEE----------DERVLEEQEMEHIASSHEH-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35119-1", "uniprot_id": "TRPC4_RAT", "id": "O35119-1", "name": "Short transient receptor potential channel 4", "aln": "---MAQFYYKRNVNAPYRDRIP-------------LRIVRAESELSPS-EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK-KPSGEKQVPPILLDKQFSEFTP--DITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRD-----DNS-LIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLN-----------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSA---------LNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEE----TKGLSCKGIRCEKQ------NNAFSTLFETLQSLFWSIFGLIN--LYVTNVKAQHEFTDFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMR------RKPESFGTIGRR----------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEG-----------------------------------------------------------LTEENVKELKQDISSFRFEVLGLLRGSKLSTIQS-ANAASSAS-SADSDEKSHSEGNGKDKRKNLSLFD---------------------LTTLIHPRSAV--------------IASERHN---LSN-GSALVVQEPPREKQRKVNFVAD-------IKNFGLFHRRSK--QNAAEQNANQIFSVSEEITRQQAAGALERNIQLE------SKGLASRGDRSIPGLNEQCVLV------DHRERNTDTLGLQVGKRVCSSFKSEKVVVEDTVPIIPKEKHAQEEDSSIDYDLSPTD---TVAHEDYVTTRL------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUQ5-1", "uniprot_id": "TRPC4_MOUSE", "id": "Q9QUQ5-1", "name": "Short transient receptor potential channel 4", "aln": "---MAQFYYKRNVNAPYRDRIP-------------LRIVRAESELSPS-EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK-KPSGEKQVPPILLDKQFSEFTP--DITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRD-----DNS-LIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLN-----------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSA---------LNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEE----TKGLSCKGIRCEKQ------NNAFSTLFETLQSLFWSIFGLIN--LYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMR------RKPESFGTIGRR----------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEG-----------------------------------------------------------LTEENVKELKQDISSFRFEVLGLLRGSKLSTIQS-ANAAS----SADSDEKSQSEGNGKDKRKNLSLFD---------------------LTTLIHPRSAA--------------IASERHN---LSN-GSALVVQEPPREKQRKVNFVAD-------IKNFGLFHRRSK--QNAAEQNANQIFSVSEEITRQQAAGALERNIELE------SKGLASRGDRSIPGLNEQCVLV------DHRERNTDTLGLQVGKRVCSTFKSEKVVVEDTVPIIPKEKHAHEEDSSIDYDLSPTD---TAAHEDYVTTRL------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBN4-1", "uniprot_id": "TRPC4_HUMAN", "id": "Q9UBN4-1", "name": "Short transient receptor potential channel 4", "aln": "---MAQFYYKRNVNAPYRDRIP-------------LRIVRAESELSPS-EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK-KPSGEKQVPPILLDKQFSEFTP--DITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRD-----DNS-LIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLN-----------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSA---------LNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEE----TKGLTCKGIRCEKQ------NNAFSTLFETLQSLFWSIFGLIN--LYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMR------RKPESFGTIGRR----------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEG-----------------------------------------------------------LTEENFKELKQDISSFRFEVLGLLRGSKLSTIQS-ANASKESSNSADSDEKSDSEGNSKDKKKNFSLFD---------------------LTTLIHPRSAA--------------IASERHN---ISN-GSALVVQEPPREKQRKVNFVTD-------IKNFGLFHRRSK--QNAAEQNANQIFSVSEEVARQQAAGPLERNIQLE------SRGLASRGDLSIPGLSEQCVLV------DHRERNTDTLGLQVGKRVCP-FKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPD---TVTHEDYVTTRL------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UL62-1", "uniprot_id": "TRPC5_HUMAN", "id": "Q9UL62-1", "name": "Short transient receptor potential channel 5", "aln": "---MAQLYYKKVNYSPYRDRIP-------------LQIVRAETELSAE-EKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYR-RPSGEKQVPTLMMDTQFSEFTP--DITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRD-----DHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH-----------------VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNG---------SRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YET-RAIDEPNNCKGIRCEKQ------NNAFSTLFETLQSLFWSVFGLLN--LYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDP---DGRRRRRNLRSFTER----------------------------------------------------------NADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEG-----------------------------------------------------------LTEENFKELKQDISSFRYEVLDLLGNRKHPR-SFSTSSTELSQRDDNNDG-----SGGARAKSKSVSFN--------------------LGCKKKTCHGPP--------------LIRTMPR--------SSGAQGKSKAESSSKRSFMGP------SLKKLGLLFSKFNGHMSEPS--SEPMYTISDGIVQQHCMWQDIRYSQME----KGKAEACSQSEINLSEVELG-----------EVQGAAQ-SSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHK----WGDGQEEQVTTRL------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QX29-1", "uniprot_id": "TRPC5_MOUSE", "id": "Q9QX29-1", "name": "Short transient receptor potential channel 5", "aln": "---MAQLYYKKVNYSPYRDRIP-------------LQIVRAETELSAE-EKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYR-KPSGEKQVPTLMMDTQFSEFTP--DITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRD-----DHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH-----------------VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNG---------SRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YET-RAIDEPNNCKGIRCEKQ------NNAFSTLFETLQSLFWSVFGLLN--LYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDP---DGRRRRHNLRSFTER----------------------------------------------------------HADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEG-----------------------------------------------------------LTEENFKELKQDISSFRYEVLDLLGNRKHPRRSLSTSSADFSQRDDTNDG-----SGGARAKSKSVSFN--------------------VGCKKKACHGAP--------------LIRTVPR--------ASGAQGKPKSESSSKRSFMGP------SFKKLGLFFSKFNGQTSEPT--SEPMYTISDGIAQQHCMWQDIRYSQME----KGKAEACSQSQMNLGEVELG-----------EIRGAAARSSECPLACSSSLHCASGICSSNSKLLDSSEDVFETWGEACDLLMHK----WGDGQEEQVTTRL------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AXK0-1", "uniprot_id": "A0A8M3AXK0_DANRE", "id": "A0A8M3AXK0-1", "name": "", "aln": "MNPMSHLYYKKSSYSPYRDRIP-------------LQIVRAEVELSPE-ERAFLSAVEKGDYAGVQHALREAEVYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHR-KPSGEKQVPSLMMDAQFSEFTP--DITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRD-----DQSEELDPRECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH-----------------MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNS---------SRPREEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YET-EAADEPNHCKGIRCERQ------NNAFSTLFETLQSLFWSVFGLLN--LYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWVHGRLCGSETAPPEEDTHKHENLKEFTEK----------------------------------------------------------HADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEG-----------------------------------------------------------LTEENFKELKQDISSFRYEVLDLLGNRKPPRRNYSSSSEATLRDEVSDDGEARHHSDGSSIGAKGVSFKTITPSDPSYGVSALFHSISGMEAAGTTREGKP--------------KINGLRKNPSPSSSLSSVAPARAPALSRTWRRFSRFSSSKKNSFRRLGLLFSRMGSHLPQPTGVTAATYTISDGLLHPPGAWHDLGFTRGDGPVTRSETNLNQVATLNEGGIGIGGSGVGMSTNGQRANGRDVLLTLGPLSPPSSLHCASSFSASSSRLLDSNEDVFQGLVGPCVGQMPHSSSCWVTEQDDSVTTQL------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48995-1", "uniprot_id": "TRPC1_HUMAN", "id": "P48995-1", "name": "Short transient receptor potential channel 1", "aln": "--MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKKILEENSS-GDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEER--MNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKN-----------------TMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHD---------FADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTS----KEQKDCVGIFCEQQS-----NDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSK---GKVKRQNSLKEWR-------------------------------------------------------------NLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQ-----------------------------------------------------------ATVENLNELRQDLSKFRNEIRDLLGFR----------TSKYAMFYPRN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61056-1", "uniprot_id": "TRPC1_MOUSE", "id": "Q61056-1", "name": "Short transient receptor potential channel 1", "aln": "--MMAALYPSTDLSGVSSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKKILEENSS-GDLNINCVDVLGRNAVTITIENESLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEER--MNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKN-----------------TMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHD---------FADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTS----KEQKDCVGIFCEQQS-----NDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSK---GKVKRQNSLKEWR-------------------------------------------------------------NLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQ-----------------------------------------------------------ATVENLNELRQDLSKFRNEIRDLLGFR----------TSKYAMFYPRN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QX01-1", "uniprot_id": "TRPC1_RAT", "id": "Q9QX01-1", "name": "Short transient receptor potential channel 1", "aln": "--MMAALYPSTDLSGVSSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKKILEENSS-GDLNINCVDVLGRNAVTITIENESLDILQLLLDYGCQ----------------------------------KLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVALPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFWNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEER--MNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKN-----------------TMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHD---------FADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTS----KEQKDCVGIFCEQQS-----NDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWVCSHTSK---GKVRRQNSLKEWR-------------------------------------------------------------NLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQ-----------------------------------------------------------ATVENLNELRQDLSKFRNEIRDLLGFR----------TSKYAMFYPKN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19334-1", "uniprot_id": "TRP_DROME", "id": "P19334-1", "name": "Transient receptor potential protein", "aln": "----MGSNTESDAEKALGSRLD-------------YDLMMAEEYILSDVEKNFILSCERGDLPGVKKILEEYQGTDKFNINCTDPMNRSALISAIENENFDLMVILLEHNIEVGDALLHAISEEYVEAVEELLQWE-ETNHKEGQPYSWEAVDRSKSTFTVDITPLILAAHRNNYEILKILLDRGATLPMPHDVKCGCDECVTSQMTDSLRHSQSRINAYRALSASSLIALSSRDPVLTAFQLSWELKRLQAMESEFRAEYTEMRQMVQDFGTSLLDHARTSMELEVMLNFNH----EPSHDIWCLGQRQTLERLKLAIRYKQKTFVAHPNVQQLLAAIWYDGLPGFRRKQASQQLMDVVKLGCSFPIYSLKYILAPDSEGAKFMRKPFVKFITHSCSYMFFLMLLGAASLRVVQITFELLAFPWMLTMLEDWRKHERGSLPGPIELAIITYIMALIFEELKSLYSDGLFEYIMDLWNIVDYISNMFYVTWILCRATAWVIVHRDLWFRGIDPYFPREHWHPFDPMLLSEGAFAAGMVFSYLKLVHIFSINPHLGPLQVSLGRMIIDIIKFFFIYTLVLFAFGCGLNQLLWYYAELEKNKCYHLHPDVADFDDQEKACTIWRRFSNLFETSQSLFWASFGLVD--LVSFDLAGIKSFTRFWALLMFGSYSVINIIVLLNMLIAMMSNSYQIISERADTEWKFARSQLWMSYFEDGGTIPPPFNLCPNMKMLRKTLGRKRPSRTKSFMR---KSMERAQTLHDKVMKLLVRRYITAEQRRRDDYGITEDDIIEVRQDISSLRFELLEIFTNNNWDVPDIEKKSQGVARTTKGKVMERRILKDFQIGFVENLKQEMSESESGRDIFSSLAKVIGRKKTQKGDKDWNAIARKNTFASDPIGSKRSSMQRHSQRSLRRKIIEQANEGLQMNQTQLIEFNPNLGDVTRATRVAYVKFMRKKMAADEVSLADDEGAPNGEGEKKPLDASGSKKSITSGGTGGGASMLAAAALRASVKNVDEKSGADGKPGTMGKPTDDKKAGDDKDKQQPPKDSKPSAGGPKPGDQKPTPGAGAPKPQAAGTISKPGESQKKDAPAPPTKPGDTKPAAPKPGESAKPEAAAKKEESSKTEASKPAATNGAAKSAAPSAPSDAKPDSKLKPGAAGAPEATKATNGASKPDEKKSGPEEPKKAAGDSKPGDDAKDKDKKPGDDKDKKPGDDKDKKPADNNDKKPADDKDKKPGDDKDKKPGDDKDKKPSDDKDKKPADDKDKKPAAAPLKPAIKVGQSSAAAGGERGKSTVTGRMISGWL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . *: :: : ::** *: * * . ..: ** * :.*.*: :****.:::: :**... : .. : *::*::**** *****:.:*:.: .::* ** : * * * :.. ******: *:: *:.*::.:*: *:..**.* **.*. :*:.*. :* ** :* *: : : *...** ::*.* *** :**. * :**:**:*.** **::.* **:* : *:. :.*:**: ::: . :* :*. *: *:::* * . :::.**:*** * .**: **::* * . . :: :: :::.::: ::* :: *: ::: : * :.: * :*:: : : .* *. *. :.* *:.*. ** . ::* *:*. ::: .. *****:*:*:*: *: **: :: ***::* **.** . * * .:: * :*** *.* : . ..: * . :.*:*.:: ::** ::*:**: :*:* *::: * ******::**:***:: *:*.***: *. * .: ..: . :.:: : :: :. . : : :..: : :: .*. :: .: . ", "identical_positions": 179, "similar_positions": 248, "identity": "13.75%" }, { "cls_id": "homologset.agr.FB:FBgn0003862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0L3-1", "uniprot_id": "F1M0L3_RAT", "id": "F1M0L3-1", "name": "Histone-lysine N-methyltransferase", "aln": "-----------MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPAGGGGPGAPPSPPAVAAAAAAG------SSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKASPRKPRGRPRSGSDRNPAILSDPSVFSPLNKSETKSTDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDIAELTQGSKEDSLKKVKRTPSAMFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQ------LLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLES--TPNSRFSATSCGSSEKSSAASQHSSQMSSDSSRSSSPSIDTTSDSQASEEIQALPEERSNTPEVHTPLPISQSPENESNDRRGRRYSMSERSFGS--RTTKKL-PTLQSAPQQQTSSSPPPPLLTPPPPLQPASGISDHTP-WLMPPTIPLASPFLPASAAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGSAASARLFSPLHSGTRFDIHKRSPILRAPRFTPSEAHSRIFESVTLPSNRTSSGASSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSTSELSPLTPPSSVSSSLSIPVSPLAASALNPTFTFPSHSLTQSGESTEKSQRARKQTSAPAEPFSSNSP-ALFPWFTPGSQTEKGRKKDTAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSDIQSSSALYPVGRVSKEKVAGEDVGTSSSAKKATGRKKSSSLDSGADIAPVTLGDTTAVKAKILIKKGRGNLEKNNLDLGPTAPSLEKEKTLCLSTPSPSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLS-ALPWEER-----EKILSSMGNDDKSSIAGSEDAEPLAP-----PIKPIKPVTRNKAPQEPPVK-KGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQTKAVKKKEKKSKATEKKESKESTVVKSSLESAQKAAPPVREEPAPKKSSSEPPPRKPVEEKTEEGGAPAPAPAPAPAPAPAPAPAPAPAPAPEPKQASTPASRKSSKQVSQPAAVVPPQPPSTALQKKEAPKAIPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKDKEKPPPV----------------------------SKQENAGTLNILNPLLNGISSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLE------------------------------DQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCEGLSGTEDEMYEILSNLP-ESVAYTCVNCTERHPA------EWRLALEKELQASLKQVLTALLNSRTTSHLLRYRQAAKPPDLN----PETEESIPSRSSPEGPDPPVLTEVSKQDEQQPLDLEGVKKKMDQGNYVSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSR-----------------FWEPNKVSNNSGMLPNAVLPPSLDHNYAQWQEREESSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELHPPPGIDDNRQCALCLMYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHR------DLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPESVHVMIGSMTIDCLGILN-DLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCK--------------------IMECRPPVVEPDINSTVEHDDNRTIAHSPSSFIEASCKDSQ-STAAILSPPSPDRP-RSQASSSCYCHVISKVP----------RIRTPSYSPTQRSPG---CRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSP----LRSKLRIMSPVRSGSVYSRSSVSSVPSLGTATDPESSAKATDRA-GPLNSSANLGHSTPVSSGSQRTVVTGGSKTSHLDGSSSSGVKRSSASDLAPKGSSLKGEKNRTPGSKSTDGSAHNTAYSGIPKLAPQVLNAAPGELNVSKIGTFAEPSTVPFS-KETVSYPQLHLRGQRSDRDQHMDSTQSVKPSPNEDGEIKTLKLPGMGHRPSILHEHVGSSSRDRRQKGKKSSKETCKEKHSSKSFLEPGQVTTGEEGNLKPEFADEVLTP----GFLGQRPCNNVSSDKTGDKILPLSGVPKGQSTQVEGSSKELQAPRKCSVKVT--PLKMESENQSKNTQKESGPGSPAHMESACPAEPASASRSPGAGPGVQPSPNNTSSQDPQSNNYQNLPEQDRNLMIPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGDERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATSRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVIKSAVGHKNEPKLDNCHSVSRVKAQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLTLGEGLGLDSNREKDMGLFEVFSQQLPATEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNSSRLAVISDSGEKRVTITEKSVTSTEGDPALLSPGVDPAPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTL------PNGVTQKIQLTSPVSSTPNVMETNTSVLGPMGSGLTLTTGLNPSLPPSQSLFPPASKGLLSMPHHQHLHSFPAA---AQSSFPPNISSPPSGLLIGVQPPPDPQLLGSEANQRTDLTTTVTTPSSGLKKRPISRLHTRKNKKLAPSSAPSNIAPSDVVSNMTLINFTPSQLSNHPSLLDLGSLNPSSHRTVPNIIKRSKSGIMYFEQAPLLPPQSVGGTTATGAGSSTISQDTSHLTSGPVSALASGSSVLNVVSMQTTTTPTSSTSVPGHVTLANQRLLGTPDIGSISHLLIKASHQSLGIQDQPVALPQSSGMFPQLGTSQTPSAAAMTAASSICVLPSSQTAGMTAASPPREAEEQYKLQRVNQLLAGKTGTLSLQRDRDPDSAPGTQPSNFTQTAEAPNGVRLEQNKTLPSAKQASSTSPG---SSPSSGQQSGSSSVPGPTKPKPKVKRI-QLPLDKGSGKKHKVSHLRTSS-EAHIPHREANPAPQPSVKRTPRADREQQEAAGVEQPSQKECGQPAGPATALPEIQATQNPANEQENAEPKAVEEEESSFSSPLMLWLQQEQKRKESITERKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLS---FAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKP--------------------------------------EEANE-PPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55200-1", "uniprot_id": "KMT2A_MOUSE", "id": "P55200-1", "name": "Histone-lysine N-methyltransferase 2A", "aln": "-----------MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPQAGGGGPGAPPSPPAVAAAAAG-------SSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKASPRKPRGRPRSGSDRNPAILSDPSVFSPLNKSETKSADKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDIAELTQGSKEDSLKKVKRTPSAMFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRIIPSCKRTDATIAKQ------LLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPMKIARLES--TPNSRFSATSCGSSEKSSAASQHSSQMSSDSSRSSSPSIDTTSDSQASEEIQALPEERSNTPEVHTPLPISQSPENESNDRRSRRYSMSERSFGS--RATKKL-PTLQSAPQQQTSSSPPPPLLTPPPPLQPASGISDHTP-WLMPPTIPLASPFLPASAAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDIHKRSPILRAPRFTPSEAHSRIFESVTLPSNRTSSGASSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSTSELSPLTPPSSVSSSLSIPVSPLAASALNPTFTFPSHSLTQSGESTEKNQRARKQTSALAEPFSSNSP-ALFPWFTPGSQTEKGRKKDTAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSDIQSSSALYPVGRVSKEKVAGEDVGTSSSAKKATGRKKSSSLDSGADVAPVTLGDTTAVKAKILIKKGRGNLEKNNLDLGPAAPSLEKERTPCLSAPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLS-ALPWEER-----EKILSSMGNDDKSSVAGSEDAEPLAP-----PIKPIKPVTRNKAPQEPPVK-KGRRSRRCGQCPGCQVPEDCGICTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKASLQKQTKAVKKKEKKSKTTEKKESKESTAVKSPLEPAQKAAPPPREEPAPKKSSSEPPPRKPVEEKSEEGGAPAPAPAP------------------EPKQVSAPASRKSSKQVSQPAAVVPPQPPSTAPQKKEAPKAVPSEPKKKQPPPPEPGPEQSKQKKVAPRPSIPVKQKPKDKEKPPPV----------------------------SKQENAGTLNILNPLSNGISSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLE------------------------------DQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCESLSGTEDEMYEILSNLP-ESVAYTCVNCTERHPA------EWRLALEKELQASLKQVLTALLNSRTTSHLLRYRQAAKPPDLN----PETEESIPSRSSPEGPDPPVLTEVSKQDEQQPLDLEGVKKRMDQGSYVSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSR-----------------FWEPNKVSNNSGMLPNAVLPPSLDHNYAQWQEREESSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIDDNRQCALCLMYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHR------DLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILN-DLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCK--------------------IMECRPPVVEPDINSTVEHDDNRTIAHSPSSFIDASCKDSQ-STAAILSPPSPDRP-HSQTSGSCYYHVISKVP----------RIRTPSYSPTQRSPG---CRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSP----LRSKLRIMSPVRTGSAYSRSSVSSVPSLGTATDPEASAKASDRG-GLLSSSANLGHSAPPSSSSQR--TVGGSKTSHLDGSSPSEVKRCSASDLVPKGSLVKGEKNRTSSSKSTDGSAHSTAYPGIPKLTPQVHNATPGELNISKIGSFAEPSTVPFSSKDTVSYPQLHLRGQRSDRDQHMDPSQSVKPSPNEDGEIKTLKLPGMGHRPSILHEHIGSSSRDRRQKGKKSSKETCKEKHSSKSYLEPGQVTTGEEGNLKPEFADEVLTP----GFLGQRPCNNVSSEKIGDKVLPLSGVPKGQSTQVEGSSKELQAPRKCSVKVT--PLKMEGENQSKNTQKESGPGSPAHIESVCPAEPVSASRSPGAGPGVQPSPNNTLSQDPQSNNYQNLPEQDRNLMIPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSNSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATSRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVIKSAVGHKNEPKLDNCHSVSRVKAQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNAELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLTLGEGLGLDSNREKDIGLFEVFSQQLPATEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSEGDPALLSPGVDPAPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNSQDLTRNSGTPGLQVPVSPTVPVQNQKYVPSSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTL------PNGVTQKIQLTSPVSSTPSVMETNTSVLGPMGSGLTLTTGLNPSLPPSPSLFPPASKGLLSVPHHQHLHSFPAA---AQSSFPPNISSPPSGLLIGVQPPPDPQLLGSEANQRTDLTTTVATPSSGLKKRPISRLHTRKNKKLAPSSAPSNIAPSDVVSNMTLINFTPSQLSNHPSLLDLGSLNPSSHRTVPNIIKRSKSGIMYFEQAPLLPPQSVGGTAATAAGSSTISQDTSHLTSGPVSALASGSSVLNVVSMQTTAAPTSSTSVPGHVTLANQRLLGTPDIGSISHLLIKASHQSLGIQDQPVALPPSSGMFPQLGTSQTPSAAAMTAASSICVLPSSQTAGMTAASPPGEAEEHYKLQRGNQLLAGKTGTLTSQRDRDPDSAPGTQPSNFTQTAEAPNGVRLEQNKTLPSAKPASSASPG---SSPSSGQQSGSSSVPGPTKPKPKAKRI-QLPLDKGSGKKHKVSHLRTSS-EAHIPHRDTDPAPQPSVTRTPRANREQQDAAGVEQPSQKECGQPAGPVAALPEVQATQNPANEQENAEPKAMEEEESGFSSPLMLWLQQEQKRKESITERKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLS---FAGVNGLRMLGILHDAVVFLIEQLAGAKHCRNYKFRFHKP--------------------------------------EEANE-PPLNPHGSARAEVHLRQSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03164-1", "uniprot_id": "KMT2A_HUMAN", "id": "Q03164-1", "name": "Histone-lysine N-methyltransferase 2A", "aln": "-----------MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAG-----SSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPRSGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQ------LLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLES--TPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS--RTTKKL-STLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTP-WLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLS-ALPWEER-----EKILSSMGNDDKSSIAGSEDAEPLAP-----PIKPIKPVTRNKAPQEPPVK-KGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPES--------------------KQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPV----------------------------NKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLE------------------------------DQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLS---DEMYEILSNLP-ESVAYTCVNCTERHPA------EWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLN----PETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSR-----------------FWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHR------DLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILN-DLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCK--------------------IVECRPPVVEPDINSTVEHDENRTIAHSPTSFTESSSKESQ-NTAEIISPPSPDRPPHSQTSGSCYYHVISKVP----------RIRTPSYSPTQRSPG---CRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSP----QRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTP----EYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTL------PNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAA---TQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLP-QSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKTGIHSSQRD--LDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRF-QLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLT--SGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQLS---FAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKP--------------------------------------EEANE-PPLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K1E3-1", "uniprot_id": "A0A0G2K1E3_RAT", "id": "A0A0G2K1E3-1", "name": "Histone-lysine N-methyltransferase 2B", "aln": "MAAAAGGGSCPGPGSARGRFPGRPRGSGGGGGRGGRGSG-AERVRVALRRGGGAAGPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGARVQRGRGRGRGRG-WGPNRGCMPEEESSDGESEEEEFQGFHSDEDVAPSS------LRSALRSQRGRAPRGR-------GRKHKTTPLPP-RLADVAPAPPKAPTRKK-GEEGTERMVQALTELLRRARAPQPPRSRARAREPSTPRRSRGRP---PGRPAGPCRKKQQAVVVAEAAVTIPKSEPPPPVVPVQHKAGSWKCKEGPGPGPGTPKRGGQPGRGGRGGRGRGRGG-LPLMIKFVSKAKKVKMGQLSQGLESGQGRGQRGESWQDAPQRRDGDEQERGPCRKKQEQKLEEEGEEKG------EKEDDSEDNSKQQEEEDTERAVAEEEVMLAKEKEEAKLPSPPLTPPVPSPPPPLPPPSTSPPP-ASPLPPP-VSPPPPPSPPPYPAPEKQEESPP-LVPATCSRKRGRPP--LTPSQRAEREAARSGPEGTLSPTANPSSTTGSPVEDSPTVVPKSTTFLKNIRQFIMPVVSARSS-RVIKTPRRFMDEDPPKPPKVEAS-IVRPPVATSPLAPQEPVPVSSPPRVPTPPSTPVPLPEKRRSILREPTFRWTSLTR-------------------------ELPPPPPAPPP--APSPPPAPATPS-----------------RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGALEAPEPELPPADD-----SPAEPEPR--------AVGRTNHLSLPRFVP--VVTTPVKVEMPPHGAPALSEG---QQLQLQQPPQALQTQLLPQALPPQQPQMQPPPSP------------------QHTPPLEKTR------------------------------------------------------------------------------------VASLGPLPLSGVEEKMFSLLKRAKVQLFKIDQ-------QQQQKVAASMP-PSPAVQTEEAVGTVKQTPDRGCVRSE------------------------DESMEAKRDGASGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLS-ALPLRDRQDLATEDTSSASETESVPSRSQREKVESAGPGGDSEPTGSAGALAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCD-------KIEARKMERLAKKGRTIVKTLLPWDSDES----------PEASPGP---PGPRRGAGAGGPREEVG--------ATPGPEE---------------------QDSLLLQRKSARRCVKQRPSYDVFEDSDDSEPGGPPAPRRRTPREHELPMLEP-EEQSRPRKPTLQPVLQLKARRR-------------------------------------LDKDALAPGPFASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLP------------------------------QHRDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRRRRHWICSACVRCKSCG-ATPGKNWDVEWSGDYSLCPRCTELYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLS---DEDYEILSGLP-DSVLYTCGPCAGATQP------RWREALSGALQGGLRQVLQGLLSSKVAGPLLLCTQCGQD--------------------------------GKQLHPGPCDLQAVGRRFEEGHYKSVHSFMEDVVAILMR--HSEEGETPERRAGHQMKGLLLKLLESAFCWFDAHDPK-----------------YWRRSTRLPN-GVLPNAVLPPSLDHVYAQWRQQE----------------------SETPESGQPPGDPSAAFQSKDPAAFS--------HLDDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHT------DLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFLTGLEPDVINVLIGSIRINSLGTLS-DLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCR--------------------ILEYRPWGPREEPVHLETAEENQTIVHSPAPSSEPPNHDDL-PDTDSLVPGDPVHLSPIQNLDPPLRTDSSNGPPPTPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDSDFPAPPR--RSRRPSPLATRP----PPS-RRTSSPLRTSPQLRVPLSTSV---LTPTSGELAPPDLAPS--PLPPSEDLGP----------------------DFEDMEVVSGLSAADLDFAASLLGTEP------------------------------------------------------------------------------------------------------------------------------------------------------------FQEEIVAA----GAMG------------------------------------------------------------------------------------SSQGGPGDSSEEEASPTTR------------------------------------------------------------------------------------------------------YVHFPVTVVSG---PTLASSSLAG------APRIEQLDGVDDGTDSEAEAVQQPR-----------GQGTP------PSGPAVGRGGVLGAAGDRARPPED---------------------------------------------------------------LPSEIVDFVLKN------LG-------------GPGEGAAGPRE----------DSLPSAPPLAN--------------------------------------------------------------------------------------------------------------------GSQPPQSLSTNPADPTRTFAWLPG---APGVRVLSLGPAPEPP---KPATSKIILVNKLGQVFVKMAGE------GEPVVPPVKQPS------------------------LPPIIPPTAPTSWTLPPGPLLSVLPVVGVGVVRPAPPP---PPPPLTLVFSSGPP-----------------------------SPPRQAIRVKRVSTFSGR-----SPPVPPPNKAP----------------------RLDEDGDSLEDTHHVP----------------------------------------------------GVSGSGLSRVRMKTP-------TVRGVLDLNNP------------------------------------------------------------------------------------------------------------------------------------------GEHPEEESPG-----------------------RPQDRCP-LLPLP--------------------------------------------------EAPSR----TLDGPSDLLFESQWHHH----YSAGEASSSEEE------------PPSPEDKENQVPKRAGPHLRFEISSDDGFSVEAESLEVAWRTLIEKVQEARGHARLRHLS---FSGMSGARLLGIHHDAVIFLAEQLPGAQHCQHYKFRYHQQ--------------------------------------GEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08550-1", "uniprot_id": "KMT2B_MOUSE", "id": "O08550-1", "name": "Histone-lysine N-methyltransferase 2B", "aln": "MAAAAGGGSCPGPGSARGRFPGRPRGSGGGGGRGGRGNG-AERVRVALRRGGGAAGPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGARVQRGRGRGRGRG-WGPNRGCMPEEESSDGESEEEEFQGFHSDEDVAPSS------LRSALRSQRGRAPRGR-------GRKHKTTPLPP-RLADVTPVPPKAPTRKR-GEEGTERMVQALTELLRRSQAPQPPRSRARAREPSTPRRSRGRP---PGRPAGPCRKKQQAVVLAEAAVTIPKPEPPPPVVPVKNKAGSWKCKEGPGPGPGTPKRGGQPGRGGRGGRGRGRGG-LPLMIKFVSKAKKVKMGQLSQELESGQGHGQRGESWQDAPQRKDGDEPERGSCRKKQEQKLEEEEEEEEKEGEEKEEKDDNEDNNKQEEEEETERAVAEEEAMLAKEKEEAKLPSPPLTPPVPSPPPPLPPPSTSPPPPASPLPPP-VSPPPPLSPPPYPAPEKQEESPP-LVPATCSRKRGRPP--LTPSQRAEREAARSGPEGTLSPTPNPSTTTGSPLEDSPTVVPKSTTFLKNIRQFIMPVVSARSS-RVIKTPRRFMDEDPPKPPKVEAS-IVRPPVATSPPAPQEPVPVSSPPRVPTPPSTPVPLPEKRRSILREPTFRWTSLTR-------------------------ELPPPPPAPPP--APSPPPAPATPS-----------------RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGALETPEPELPPADD-----SPAEPEPR--------AVGRTNHLSLPRFVP--VVTSPVKVEVPPHGAPALSEG---QQLQLQQPPQALQTQLLPQALPPQQPQAQPPPSP------------------QHTPPLEKAR------------------------------------------------------------------------------------VASLGSLPLSGVEEKMFSLLKRAKVQLFKIDQ-------QQQQKVAASMP-LSPAVQTEEAVGTVKQTPDRGCVRSE------------------------DESMEAKRDRASGPESPLQGPRIKHVCRHAAVALGQARAMVPEDVPRLS-ALPLRDRQDLATEDTSSASETESVPSRSQREKVESAGPGGDSEPTGSTGALAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCD-------KIEARKMERLAKKGRTIVKTLLPWDSDES----------PEASPGP---PGPRRGAGAGGSREEVG--------ATPGPEE---------------------QDSLLLQRKSARRCVKQRPSYDVFEDSDDSEPGGPPAPRRRTPREHELPVLEP-EEQSRPRKPTLQPVLQLKARRR-------------------------------------LDKDALAPGPFASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPSP------------------------------QHRDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRRRRHWICSACVRCKSCG-ATPGKNWDVEWSGDYSLCPRCTELYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLS---DEDYEILSGLP-DSVLYTCGPCAGATQP------RWREALSGALQGGLRQVLQGLLSSKVAGPLLLCTQCGQD--------------------------------GKQLHPGPCDLQAVGKRFEEGLYKSVHSFMEDVVAILMR--HSEEGETPERRAGSQMKGLLLKLLESAFCWFDAHDPK-----------------YWRRSTRLPN-GVLPNAVLPPSLDHVYAQWRQQE----------------------SETPESGQPPGDPSAAFQSKDPAAFS--------HLDDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHT------DLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFLTGLEPDVINVLIGSIRINSLGTLS-DLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCR--------------------ILEYRPWGPREEPVHLEAAEENQTIVHSPTPSS----------DTDSLIPGDPVHHSPIQNLDPPLRTDSSNGPPPTPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDSDFPAPPR--RSRRPSPLATRP----PPS-RRTSSPLRTSPQLRVPLSTSVT-ALTPTSGELAPPDLAPS--PLPPSEDLGP----------------------DFEDMEVVSGLSAADLDFAASLLGTEP------------------------------------------------------------------------------------------------------------------------------------------------------------FQEEIVAA----GAVG------------------------------------------------------------------------------------SSQGGPGDSSEEEASPTTH------------------------------------------------------------------------------------------------------YVHFPVTVVSG---PALAPSSLAG------APRIEQLDGVDDGTDSEAEAVQQPR-----------GQGTP------PSGPGVGRGGVLGAAGDRAQPPED---------------------------------------------------------------LPSEIVDFVLKN------LG-------------GPGEGAAGPRE----------DSLPSAPPLAN--------------------------------------------------------------------------------------------------------------------GSQPPQSLSTSPADPTRTFAWLPG---APGVRVLSLGPAPEPP---KPATSKIILVNKLGQVFVKMAGE------GEPVAPPVKQPP------------------------LPPIIPPTAPTSWTLPPGPLLSVLPVVGVGVVRPAPPP---PPPPLTLVFSSGPP-----------------------------SPPRQAIRVKRVSTFSGR-----SPPVPPPNKTP----------------------RLDEDGESLEDAHHVP----------------------------------------------------GISGSGFSRVRMKTP-------TVRGVLDLNNP------------------------------------------------------------------------------------------------------------------------------------------GEQPEEESPG-----------------------RPQDRCP-LLPLA--------------------------------------------------EAPSQ----ALDGSSDLLFESQWHH-----YSAGEASSSEEE------------PPSPEDKENQVPKRVGPHLRFEISSDDGFSVEAESLEVAWRTLIEKVQEARGHARLRHLS---FSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQ--------------------------------------GEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMN6-1", "uniprot_id": "KMT2B_HUMAN", "id": "Q9UMN6-1", "name": "Histone-lysine N-methyltransferase 2B", "aln": "MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNG-AERVRVALRRGGGATGPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRG-WGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSS------LRSALRSQRGRAPRGR-------GRKHKTTPLPPPRLADVAPTPPKTPARKR-GEEGTERMVQALTELLRRAQAPQAPRS--RACEPSTPRRSRGRP---PGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKK------------EEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPP--LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS-RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTR-------------------------ELPPPPPAPPPPPAPSPPPAPATSS-----------------RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADD-----SPAEPEPR--------AVGRTNHLSLPRFAP--VVTTPVKAEVSPHGAPALSNGP-QTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSP------------------QQMPPLEKAR------------------------------------------------------------------------------------IAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQ-------QQQQKVAASMP-LSPGGQMEEVAGAVKQISDRGPVRSE------------------------DESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLS-ALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCD-------KIEARKMERLAKKGRTIVKTLLPWDSDES----------PEASPGP---PGPRRGAGAGGPREEVV--------AHPGPEE---------------------QDS-LLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEP-EEQSRPRKPTLQPVLQLKARRR-------------------------------------LDKDALAPGPFASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLP------------------------------QHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCG-ATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLS---DEDYEILSGLP-DSVLYTCGPCAGAAQP------RWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPD--------------------------------GKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMR--HSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPK-----------------YWRRSTRLPN-GVLPNAVLPPSLDHVYAQWRQQE----------------------PETPESGQPPGDPSAAFQGKDPAAFS--------HLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHT------DLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTLS-DLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCR--------------------ILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPR--RSRRPSPLAPRP----PPS-RWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPS--PPPP-EDLGP----------------------DFEDMEVVSGLSAADLDFAASLLGTEP------------------------------------------------------------------------------------------------------------------------------------------------------------FQEEIVAA----GAMG------------------------------------------------------------------------------------SSHGGPGDSSEEESSPTSR------------------------------------------------------------------------------------------------------YIHFPVTVVSA---PGLAPSATPG------APRIEQLDGVDDGTDSEAEAVQQPR-----------GQGTP------PSGPGVVRAGVLGAAGDRARPPED---------------------------------------------------------------LPSEIVDFVLKN------LG-------------GPGDGGAGPRE----------ESLPPAPPLAN--------------------------------------------------------------------------------------------------------------------GSQPSQGLTASPADPTRTFAWLPG---APGVRVLSLGPAPEPP---KPATSKIILVNKLGQVFVKMAGE------GEPVPPPVKQPP------------------------LPPTISPTAPTSWTLPPGPLLGVLPVVG--VVRPAPPP---PPPPLTLVLSSGPA-----------------------------SPPRQAIRVKRVSTFSGR-----SPPAPPPYKAP----------------------RLDEDGEASEDTPQVP----------------------------------------------------GLGSGGFSRVRMKTP-------TVRGVLDLDRP------------------------------------------------------------------------------------------------------------------------------------------GEPAGEESPG-----------------------PLQERSP-LLPLPE-------------------------------------------------DGPPQ----VPDGPPDLLLESQWHH------YSGEASSSEEE------------PPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLS---FSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQ--------------------------------------GEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I022-1", "uniprot_id": "A0AC58I022_DANRE", "id": "A0AC58I022-1", "name": "[histone H3]-lysine(4) N-methyltransferase", "aln": "-------------------------MAAAGGGLAASAVVATVNTTATVRCRFPGRPWTARSLQRTEKRSHVGRVRAEDRKGPRPVDVGATLREDPCLSRLLGLAEKHRRQREAGFCTSDEEEGDFTGFNVDGQWSLRSG----------------------------KSSNRALKLASSKVKRSSAADLKSSILKKPGMRGR--------PFSRTDQKSVRPKMVVKVAAKRVTKRETKKP--------------------------SVNGDGHLKQGSSSKTNGRVLRNQREGTRVSSLTENDKTTVDEDDTNVKSQTHGSSAAEKLVWTLTLVKGKERASKLKDTQGQRASADYTKRVKTKGVTAGDEAEEVSAKPMAKQK-------------------RGRKSAADKLALKSPGTDVGASLSDRVLISSQRKPFVRRRKRGQRRLLLKKVHRKVPDSQRQASS-------------------------MPRKRQRLSVSDTDPINVLQPVEGQEQALLESTSGGQAEELKHPTKPTVSARSSRVIKIPKRFMDDERMSALPERAALKK-PALTELPTDLSKPNTDHQTLESGSRLKTTQELDIVND-----------------DEKSVLEKMQSQGVKPALSSSRLSG---------------------------------------------------------------------GARGRGGRIGQSADHYKIYWKLKKLTACLAKRKMQRMAGDSSR----LTEEDAEEG-----------TQGTREQKSDLKLQDIYSPGVVPKVAIRVGDHSDQTPLASLAEASSKENVETDNLEDSTETSAQNEQQGGIP--------------------------------------------------------------------------------------------------------------------QRMSVSGANRRMIHLLKRARVQLIKIDQ-------QKQLKSAQLLSGTVKAREGPATAGRRGRKKGTRKVRAN--------------------------------PEVAPQAQLIGGPRIKHVCRAAAVALGQPRALVPDDIPRLS-ALPLHER-----EGITASPVEEDVASHSEPESEESVET-----------------KPSFIKSLPLGCRLRRCNRCKGCNRLEDCGRCVFCLDKPKFGGPNKKRQSCVLKKCAMIE----RNKMRKFNKVQVKRRRPSAPPATNSSEEENEEERGDDGGGGLAQFSPTRRQPRRRVTPRSYRKMLGYDDSDTESASSDQTKPSG--------TQKTQITADTTATSAAPPEEATKQKRQGLYRAFWAQRRNDKKLEPPSSCSSSLDPPAPSHHPLTLTGSPSKKTKRRLQLRLKRLPASVVQAAMLGLTLPQSESQRVLCEEPVFTHCSSVTHSQSSVEHTPSSVLTPLSNGCTQRGKLSQGSMNKIRVDFKEDCNIQNVWLMGGLSILTSVPIMPQCVCLLCASKGQHEMVYCQMCCEPFHHFCLPPDDRPKE------------------------------ENKENWCCRRCKFCHVCGRKSKQTKPVLQCKRCMYCYHPSCLGPTYP-KPVKMNTSWVCMLCIRCKSCG-VTPGKSSDTSWNHELELCPDCNKLHSKGDFCTVCLKCYEEHEFDSSMMQCARCAHWVHPKCEGLT---DDLHEILCRLRGKSLVFSCAPCSKSFCS------GWQDVVQEVLRNGLEKIMGGLKNSLNISHLRLCAQCEACP-----------------------------DFEVVKGRSGCCLHPVEKKLENGLYTSLKSFHEDVVKVMVERLRREEYLLEAQRPTSQAKLYYIKLVEQVFSWFNSQDPK-----------------TWSSNVQEFPRGMLPEAIIPPSNEHSYAQWLKDQH---------------------PGSPQSKDQQKINSKPLD--------------------ERQCSLCQQHGDAKPNDAGRLLYIGQNEWAHVNCCIWSAEVQETN-GALLHVHSAVARGRFMRCERCGQTGATVGCCLTSCQSNYHFMCARASNCVFQHDKKVYCYKHR------ELINS-KIEQGNGFEVVRRVYVDFDGISLRRKFLTGLEPESVNVMIGSLHVKNLGVLT-ELSANSGKLYPVGYQCSRWYWSTVDPRRRCRYTCK--------------------VSEVRPSTRCRTPSFMVDQGENHTIVHSPKAQNDEDGTDSE-----SFSPGLPLSTPSKTKQDSGSGG------------------RTPGYPHSRRPAGG-MSRPLPSPGNALSTSHHILTISDLDETRRSTRRHSTRSRNASPPP----VILSGPMALRSGGSINPRSLSFSPPVSPLGATENLMSTTSPRRRGRPPSLSPSSIISGPSPPQAALRSPSSALPSTVHHSPRLQQPFTTSPHKTDKVVQDFLSEPEEAAG-----------------------------------------------------------------------------------------------------------------------APVLKSDHDLLSPHFDPDTDVAVASVLNAKLEFDEALLNENVALD---------------------------------------------------------------------------------------CDPQGAEGELEEEACKYNAGRKDLSS--------------------------------------------------------------------------------IAEMQMETDDEVADHYLNFSRTVVVCEPAKDTQTGLTVLP----NSGSISQLDGADNDSESDTGEANADDNTQEVGSSFLSQDTEPLKITGQNKGTTLGDGQLVCTEIANPHTADS----------------------------------------------------------------VDENAKPETQNIEQVCEEQEVSSLEDNANLLVDAGSDSSNQQE------MSFTDGLNATTPVVYKGSD---------------------------------------------------------------------------------------------------------------LIATQEEILAESESSAGSQEVFLDDTSGNFICTVDGRVVDSPKNTADPEGSRDSVPINKENVVLNRALSP------VEKPAAAVKSSATR--------TFHVVAPSMPAKRRFVTIQPGSQPKTFQMAMPVATSIPISVPINVVSTSPTF---SVAPHGTQFTPSPVVIN-----------------------GFGAIPKEALKGRRIAIRIATPKQSLPHCVPGTPPTPQVLLVNRAGQILVKNPQNNTYQIPSANSPSYTQISQIARIIHG----------------------------SNVLQRPVPKVTVMPVPQLQACLSRTSPARIISYSSNSGAAPPTQVLIRRIPQSFPGGQLSGVSPPLEKAGSISEGGQ--------------------------------------------------------------------------------------------KELAQVIIDKAMASHREVANATTASPSLLGKRLSPESKKSSTLRTQPNILANSRSQVRIKRVSSVTERIGVKRCKTDFLDQMAPSSQDDHSRSNRVRIKAPSVKEVLDFDGSFDPKNDDSKVAEHERITPKEPIATHANDSQDGGKSHILSSKLGDSSDWAPYAGWSSDEESPSPGKQEKCASLYQPHLIFQITSEDGFSVEADSMDVAWKAVMDGVQEARIGCRMEQLP---FNSINGARVLGVLHDAVLFLLEQLQGASLCQKHRFRFHQH--------------------------------------EIPEEELPENPNGCARAEVYVRKSTFDMFNFLASQHRQLPESRPCDDDEDDIMLKSSRRATSTELPVAMRFRHLEKTSKEAVGVYRSAIHGRGLFCKRNIEAGEMVIEYAGNVIRAVLTDKREKYYDSKGIGCYMFRIDDFDVVDATMHGNAARFINHSCDPNCYSRVINVEGQKHIVIFALRKIYRGEELTYDYKFPIEDADNKLHCNCGARRCRRFLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20659-1", "uniprot_id": "TRX_DROME", "id": "P20659-1", "name": "Histone-lysine N-methyltransferase trithorax", "aln": "--------------MGRSKFPGKPSKSINRKRISVLQLEDDAANPAEPQQPAPESQQPSGSGSGSSAAREKGNNCDNDEDDN--APGGASISGNTASSSAGSGNSGNGSSSGSSTGSGSSGSGSTNGGSVNGGTHHKSAANLDKEAVTKDQNGDGDKTRGN------VSSAPSGKLSAAASGKALSKSSRTFSASTSVTSSGRSSGSSPDGNSGASSDGASSGISCGKSTAKSTEASSGKLAKTTGAGTCSSAKSSKASSGTTSEATTSGLSGACLKALFVATPATSTGLACALVSPGGSSQGGTFPISAALLRARKNSNKKFKNLNLARGEVMLPSTSKLKQLNSPVVDNPSPSPPIASGSTPSVEGGIGVGGVVSPGEDAALKRVLTEMP-------NEVARDPSPSSCTAAANGAASGKGSASNGPPAMASSGDGSSPKSGADTGPSTSSTTAKQKKTVTFRNVLETSDDKSVVKRFYNPDIRIPIVSIMKKDSLNRPLNYSRGGECIVRPSILSKILNKNSNIDKLNSLKFRSAGASSSSSNQESGSSSNVFGLSRAFGAPMDEDDEGGVTFRRNDSPEDQNNAEDDEMDDDDDDEEAEEDDENEDDNDEAVSEKSAETEKSAGADERDPDEKQLVMDSHFVLPKRSTR----------------------------------SSRIIKPNKRLLEEG------------------AISTKKPLSLGDSKGKNVFGTSSSSAGSTASTFSASTNLKLGKETFFNFGTLKPNSSAAG----NFVLRQPRLQFQADNQQATFTAPKACPTSPSAIPKPANSLATSSFGSLASTNSSTVTPTPSACSICSAVVSSKEVT----------------------------------------------------------------------------------------------------------------QARKYGVVACDVCRKFFSKMTKKSISANSSTAN-------TSSGSQQYLQCKGNEGSPCSIHSAKSQLKNFKKFYKDR-----------------------CTACWLKKCMISFQLPAAHRSRLSAILPPGMRGEAAAREEKSAELLSPTGSLRFTSTASSSSPSVVASTSVKWKSSGDSTSALTSIKP-----NPLAENNVTFGSTPLLRPAILENPLFLKISNAADQKLAAAEAISPSLTKKNSKQEKEKVKESEQSEKLLSP-----TQAGTKKSGAAEAQVEEVQPQKEEAPQTSTTTQPSASNGASHGVPQAELAGETNATGDTLKRQRIDLKGPRVKHVCRSASIVLG---------------QPLATFGEDQQPEDAADMQQEIAAPVPSAIMEPSPEKPTHIVTDENDNCASCKTSPVGDESKPSKSSGSAQAEVKKATALGKEGTASAAGGSSAKVTTRNAAVASNLIVAASKKQRNGDIATSSSVTQSSNQTQGRKTKEHRQQRTLISIDFWENYDPAEVCQTG-FGLIVTETVAQRALCFLCGSTGLDPLIFCACCCEPYHQYCVQDEYNLKHGSFEDTTLMGSLLETTVNASTGPSSSLNQLTQRLNWLCPRCTVCYTCN---MSSGSKVKCQKCQKNYHSTCLG--TSKRLLGADRPLICVNCLKCKSCS-----TTKVSKFVGNLPMCTGCFKLRKKGNFCPICQRCYDDNDFDLKMMECGDCGQWVHSKCEGLS---DEQYNLLSTLP-ESIEFICKKCARRNESSKIKAEEWRQAVMEEFKASLYSVLKLLSKSRQACALLKLSPRKKLRCTCGASSNQGKLQPKALQFSSGSDNGLGSDGESQNSDDVYEFKDQQQQQQQRNANMNKPRVKSLPCSCQQHISHSQSFSLVDIKQKIAGNSYVSLAEFNYDMSQVIQQSNCDELDIAYKELLSEQFPWFQNETKACTDALEEDMFESCSGGNYEDLQDTGG------------------VSASVYNEHSTSQAESRSGVLDIPLEEVDDFGSCGIKMRLDTRMCLFCRKSGEGLSGEEARLLYCGHDCWVHTNCAMWSAEVFEEIDGSLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCAFLTDKSMYCPAHAKNGNALKANGSPSVTYESNFEVSRPVYVELD-----RKRKKLIEPARVQFHIGSLEVRQLGAIVPRFSDSYEAVVPINFLCSRLYWSSKEPWKIVEYTVRTTIQNSSSTLTALDVGRNYTVDHTNPNSKEVQLGMAQIARWHTSLARSEFLENGGTDWSGEFPNPNSCVPPDENTEEEPQQQADLLPPELKDAIFEDLPHELLDGISMLDIFLYDDKTDLFAISEQSKDGTQAMTSNQAQNQNQQAGGANSVSICDEDTRNSNTSLGNGWPASNPVEDAMLSAARNSSQVQMLKTLAWPKLDGNSAMATAIKRRKLSKNLAEGVFLTLSSQQRNKKEMATVAGVSRRQSISETSVEGVATTSGSVRSKSFTWSAAKRYFE----------------------------------------------------------------------------------------------------------------KSEGREEAAKMRIMQMDGVDDSITEFRIISGDGNLSTAQFSGQVKCDRCQCTYRN--------------------------------------------------------------------------YDAFQRHLPSCSPTMSSNETESDVSGQGMTNNATQISAESLNELQKQLLANAGGLNYLQSATSFPQVQSLGSLG----QFGLQGLQQLQLQPQSLGSGFFLSQPNPATQANTDDLQIYANSLQSLAANLGGGFTLAQPTVTAPAQPQLIAVSTNPDGTQQFIQIPQTMQATTTPTATYQTLQATNTDKKIMLPLTAAGKPLKTVATKAAQQAAVKQRQLKSGHQVKPIQAKLQPHPQQHQQQQQTQVQQPITVMGQN--------------LLQPQLLFQSSTQTQAPQIILPQAQPQNIISFVTGDGSQGQPLQYISIPTAGEYKPQPQPTATPTFLTTAPGAGATYLQTDASGNLVLTTTPSNSGLQMLTAQSLQAQPQVIGTLIQPQTIQLGGGADGNQPGSNQQPLILGGTGGGSSGLEFATTSPQVILATQPMYYGLETIVQNTVMSSQQFVSTAMPGMLSQNASFSATTTQVFQASKIEPIVDLPAGYVVLNNTGDASSAGTFLNAASVLQQQTQDDTTTQILQNANFQFQSVPTSSGASTSMDYTSPVMVTAKIPPVTQIKRTNAQAKAAGISGVGKVPPQPQVVNKVLPTSIVTQQSQVQVKNSNLKQSQVKGKAASGTGTTCGAPPSIASKPLQKKTNMIRPIHKLEVKPKVMKPTPKVQNQNHSLLQQQQQQQPQLQQQIPAVVVNQVPKVTISQQRIPAQTQQQQLQQAQMIHIPQQQQPLQQQQVQVQPSMPIITLAEAPVVQSQFVMEPQALEQQELANRVQHFSTSSSSSSSNCSLPTNVVNPMQQQAPSTTSSSTTRPTNRVLPMQQRQEPAPLSNECPVVSSPTPPKPVEQPIIHQMTSASVSKCYAQKSTLPSPVYEAELKVSSVLESIVPDVTMDAILEEQPVTESIYTEGLYEKNSPGESKTEQLLLQQQQREQLNQQLVNNGYLLDKHTFQVEPMDTDVYREEDLEEEEDEDDDFSLKMATSACNDHEMSDSEEPAVKDKISKILDNLTNDDCADSIATATTMEVDASAGYQQMVEDVLATTAAQSAPTEEFEGALETAAVEAAATYINEMADAHVLDLKQLQNGVELELRRRKEEQRTVSQEQEQSKAAIVPTAAAPEPPQPIQEPKKMTGPHLLYEIQSEDGFTYKSSSITEIWEKVFEAVQVARRAHGLTPLPEGPLADMGGIQMIGLKTNALKYLIEQLPGVEKCSKYTPKYHKRNGNVSTAANGAHGGNLGGSSASAALSVSGGDSHGLLDYGSDQDELEENAYDCARCEPYSNRSEYDMFSWLASRHRKQPIQVFVQPSDNELVP---RRGTGSNLPMAMKYRTLKETYKDYVGVFRSHIHGRGLYCTKDIEAGEMVIEYAGELIRSTLTDKRERYYDSRGIGCYMFKIDDNLVVDATMRGNAARFINHCCEPNCYSKVVDILGHKHIIIFALRRIVQGEELTYDYKFPFEDE--KIPCSCGSKRCRKYLN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . * . .. . :. . . . : . . . . . .: : . : . . . . . . . * . .: . . : . . . . :. .. : . . : : * : : . : . . .: . . :. . . . : . . ::: : :. . . . . . . .*:. : . . . * . :: : :* . :: . .* . . : ... . . . .* . : ::. .* * . .. . . *: : . : . * * :* . . . : : * : :** *: : :* * :.::.: . :*:**.*.* :::* **:*:* :*: . : .* * **..*:.*. : ::*::* **. *** . : :* *::****. . .: : :* * :* **::*.:* :**::.::: .**:*. * :***.***.*: *: :::*. * .*: : * *: . *: .: :: .* .:: * .* * :. :: :: ..: . : * : . . * . . * : :: .. * : . . : . * * :* *: . : .**** *:: *.*.**.:***** * *:* :** ** **: ::* * : ****** : ** .::*: *:*: * * **.::* * . . .: ..*:* * *:*::: ** . :** ::. ***: : ** : :* : *:.: *** ***: :. : * : : . .* : ::.:* * . . .. *. ::. . .: . . . . . :. . * : . . : . :. ..: . . ::.. : : . . . . .: . : : . : : . . : * . . : .. * : : .. . :: * . : : . . : . . . : . . . . . :.. . * ::* *:*** :.*: *. : : ** ** : *. : .:.* :::*: :*: :* *** *.. * :: ::*: :: *. ..**.* : .:. :***.:***:** * : .:::: **.*. :**:.*::* *::* *: ***:** ******:*.::*:********:* :**: *****::**.:*******::** ******:*********.*:***:*:*:.: *:***:***:*:* :***********:** *: *.**:::**::**", "identical_positions": 299, "similar_positions": 485, "identity": "7.08%" }, { "cls_id": "homologset.agr.FB:FBgn0003863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36369-1", "uniprot_id": "K1B26_MOUSE", "id": "P36369-1", "name": "Kallikrein 1-related peptidase b26", "aln": "-----------MWFLILFPALSLG---------------GIDAAPP-----------------LQSRVVGGFNCEKNSQPWQVAVYYQK--EHICGGVLLDRNWVLTAAHCYVD--------QYEVWLGKNKLFQ-EEPSAQHRLVSKSFPHPGFNMSLLMLQTTPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEP--KPGSTCLASGWGSITPTR----WQKSDDLQCVFITLLPNENCAK--------VYLQKVTDVMLCAGEMGGGKDTCAGDSGGPLICDG-----ILQGTTSNG-PEPCGKPGVPAIYTNLIKFNSWIKDTMMKNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36368-1", "uniprot_id": "EGFB2_MOUSE", "id": "P36368-1", "name": "Epidermal growth factor-binding protein type B", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------LQSRVVGGFNCKKNSQPWQVAVYYQK--EHICGGVLLDRNWVLTAAHCYVD--------QYEVWLGKNKLFQ-EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEP--KPGSKCLASGWGSITPTR----WQKPDDLQCVFITLLPNENCAK--------VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSYG-PVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04071-1", "uniprot_id": "K1B16_MOUSE", "id": "P04071-1", "name": "Kallikrein 1-related peptidase b16", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQSRIVGGFKCEKNSQPWQVAVYYHK--EHICGGVLLDRNWVLTAAHCYVD--------ECEVWLGKNQLFQ-EEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEP--KLDSTCLVSGWGSITPTK----WQKPDDLQCMFTKLLPNENCAK--------AYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDG-----VLQGTVSIG-PDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07628-1", "uniprot_id": "K1KB8_MOUSE", "id": "P07628-1", "name": "Kallikrein 1-related peptidase b8", "aln": "-----------MRFLILFLALSLG---------------GIDAAPP-----------------LQSRVVGGFNCEKNSQPWQVAVYDNK--EHICGGVLLERNWVLTAAHCYVD--------QYEVWLGKNKLFQ-EEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKES--KLGSTCLASGWGSITPTK----WQKPDDLQCVFLKLLPIKNCIE--------NHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDS-----VLQGITSTG-PIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15948-1", "uniprot_id": "K1B22_MOUSE", "id": "P15948-1", "name": "Kallikrein 1-related peptidase b22", "aln": "-----------MRFLILFLTLSLG---------------GIDAAPP-----------------VQSRILGGFKCEKNSQPWQVAVYYLD--EYLCGGVLLDRNWVLTAAHCYED--------KYNIWLGKNKLFQ-DEPSAQHRLVSKSFPHPDFNMSLL--QSVPTGADLSNDLMLLRLSKPADITDVVKPIDLPTTEP--KLGSTCLASGWGSINQLI----YQNPNDLQCVSIKLHPNEVCVK--------AHILKVTDVMLCAGEMNGGKDTCKGDSGGPLICDG-----VLQGITSWG-STPCGEPNAPAIYTKLIKFTSWIKDTMAKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61759-1", "uniprot_id": "K1B21_MOUSE", "id": "Q61759-1", "name": "Kallikrein 1-related peptidase b21", "aln": "-----------MRFLILFLALSLG---------------EIDAAPP-----------------VQSRIVGGFNCEKNSQPWHVAVFRYN--KYICGGVLLNPNWVLTAAHCYGN--------QYNVWLGKNKLFQ-HESSAQHRLVSKSFPHPDYNMSLMNDHTPHPEDDYSNDLMLLRLSKPADITDAVKPIDLPTEEP--KLGSTCLASGWGSITPTK----WQIPNDLQCGFIKPLPNENCAK--------AYIHKVTDVMLCAGEMGGGKDTCAGDSGGPLICDG-----VLQGITSWG-SIPCAKPNAPAIYTKLIKFTSWIKDTMAKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JM71-1", "uniprot_id": "K1B27_MOUSE", "id": "Q9JM71-1", "name": "Kallikrein 1-related peptidase b27", "aln": "-----------MRFLILFLALSLG---------------GIDAAPP-----------------VQSRIIGGFKCKKNSQPWHVAVLRSN--KYICGGVLLDPNWVLTAAHCYGND-----TSQHNVWLGKNKLFQ-REPSAQHRWVSKSFPHPDYNMSLLNDHIPHPED-KSNDLMLLRLSKPADITDAVKPIDLPTEEP--KLGSTCLASGWGSITPTK----YQIPNDLQCVFIKLLPNENCAK--------AYVHKVTDVMLCVGETGGGKGTCKGDSGGPLICDG-----VLHGITSWG-SIPCAKPNAPGVFTKLIKFTSWIKDTMAKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61754-1", "uniprot_id": "K1B24_MOUSE", "id": "Q61754-1", "name": "Kallikrein 1-related peptidase b24", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQSRVVGGFKCEKNSQPWHVAVFRYN--KYICGGVLLNPNWVLTAAHCYGNA-----TSQYNVWLGKNKLFQ-REPSAQHRWVSKSFPHPDYNMSLLNDDIPQPKD-KSNDLMLLRLSEPADITDAVKPIDLPTEEP--KLGSTCLASGWGSITPTK----WQKPNDLQCVFIKLLPNENCTK--------PYLHKVTDVMLCAGEMGGGKDTCAGDSGGPLICDG-----ILHGITSWG-PVPCGKPNAPAIYTKLIKFASWIKDTMAKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15946-1", "uniprot_id": "K1B11_MOUSE", "id": "P15946-1", "name": "Kallikrein 1-related peptidase b11", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQSRIVGGFNCEKNSQPWHVAVYRYN--KYICGGVLLDRNWVLTAAHCHVS--------QYNVWLGKTKLFQ-REPSAQHRMVSKSFPHPDYNMSLLIIHNPEPEDDESNDLMLLRLSEPADITDAVKPIALPTEEP--KLGSTCLVSGWGSITPTK----FQTPDDLQCVSIKLLPNEVCVK--------NHNQKVTDVMLCAGEMGGGKDTCKGDSGGPLICDG-----VLHGITAWG-PIPCGKPNTPGVYTKLIKFTNWIKDTMAKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15949-1", "uniprot_id": "K1KB9_MOUSE", "id": "P15949-1", "name": "Kallikrein 1-related peptidase b9", "aln": "-----------MRFLILFLALSLG---------------GIDAAPP-----------------VHSRIVGGFKCEKNSQPWHVAVYRYN--EYICGGVLLDANWVLTAAHCYYE--------ENKVSLGKNNLYE-EEPSAQHRLVSKSFLHPGYNRSLHRNHIRHPEYDYSNDLMLLRLSKPADITDVVKPIALPTEEP--KLGSTCLASGWGSTTPFK----FQNAKDLQCVNLKLLPNEDCGK--------AHIEKVTDVMLCAGETDGGKDTCKGDSGGPLICDG-----VLQGITSWG-FTPCGEPKKPGVYTKLIKFTSWIKDTMAKNL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00755-1", "uniprot_id": "K1KB1_MOUSE", "id": "P00755-1", "name": "Kallikrein 1-related peptidase b1", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQSRIVGGFKCEKNSQPWHVAVYRYK--EYICGGVLLDANWVLTAAHCYYE--------KNNVWLGKNNLYQ-DEPSAQHRLVSKSFLHPCYNMSLHRNRIQNPQDDYSYDLMLLRLSKPADITDVVKPIALPTEEP--KLGSTCLASGWGSIIPVK----FQYAKDLQCVNLKLLPNEDCDK--------AYVQKVTDVMLCAGVKGGGKDTCKGDSGGPLICDG-----VLQGLTSWG-YNPCGEPKKPGVYTKLIKFTSWIKDTLAQNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00756-1", "uniprot_id": "K1KB3_MOUSE", "id": "P00756-1", "name": "Kallikrein 1-related peptidase b3", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQSRIVGGFKCEKNSQPWHVAVYRYT--QYLCGGVLLDPNWVLTAAHCYDD--------NYKVWLGKNNLFK-DEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTEEP--KLGSTCLASGWGSITPTK----FQFTDDLYCVNLKLLPNEDCAK--------AHIEKVTDAMLCAGEMDGGKDTCKGDSGGPLICDG-----VLQGITSWG-HTPCGEPDMPGVYTKLNKFTSWIKDTMAKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15947-1", "uniprot_id": "KLK1_MOUSE", "id": "P15947-1", "name": "Kallikrein-1", "aln": "-----------MRFLILFLALSLG---------------GIDAAPP-----------------VQSRIVGGFNCEKNSQPWQVAVYRFT--KYQCGGILLNANWVLTAAHCHND--------KYQVWLGKNNFLE-DEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPTEEP--KLGSTCLASGWGSITPVK----YEYPDELQCVNLKLLPNEDCAK--------AHIEKVTDDMLCAGDMDGGKDTCAGDSGGPLICDG-----VLQGITSWG-PSPCGKPNVPGIYTRVLNFNTWIRETMAEND---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15945-1", "uniprot_id": "K1KB5_MOUSE", "id": "P15945-1", "name": "Kallikrein 1-related peptidase b5", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQSRIFGGFNCEKNSQPWQVAVYRFT--KYQCGGVLLNANWVLTAAHCHND--------KYQVWLGKNNFFE-DEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPTEEP--KLGSTCLASGWGSITPVI----YEPADDLQCVNFKLLPNEDCVK--------AHIEKVTDVMLCAGDMDGGKDTCMGDSGGPLICDG-----VLHGITSWG-PSPCGKPNVPGIYTKLIKFNSWIKDTIAKNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00757-1", "uniprot_id": "K1KB4_MOUSE", "id": "P00757-1", "name": "Kallikrein 1-related peptidase-like b4", "aln": "-----------MWFLILFLALSLG---------------GIDAAPP-----------------VQS----QVDCE-NSQPWHVAVYRFN--KYQCGGVLLDRNWVLTAAHCYND--------KYQVWLGKNNFLE-DEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEP--KLGSTCLASGWGSTTPIK----FKYPDDLQCVNLKLLPNEDCDK--------AHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDG-----ILQGITSWG-PEPCGEPTEPSVYTKLIKFSSWIRETMANNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "-----------MWFLILFLALSLG---------------QIDAAPP-----------------GQSRVVGGYNCETNSQPWQVAVIG----TTFCGGVLIDPSWVITAAHCYSK--------NYRVLLGRNNLVK-DEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEP--KVGSICLASGWGMTNPSE----MKLSHDLQCVNIHLLSNEKCIE--------TYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDG-----VLQGLTSGG-ATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMU8-1", "uniprot_id": "A0A8I6AMU8_RAT", "id": "A0A8I6AMU8-1", "name": "tissue kallikrein", "aln": "-----------NFFLYFFLDQVII---------------EQNAAPP-----------------GQSRVVGGYKCEKNSQPWQVAVIS----RSLCGGVLIDPSWVITAAHCYSN--------YYHVLLGRNNLSE-DEPFAQYRFVSQSFPHPDYNPFFMRNHTRQPGDDYSNDLMLLHLSKPADITDGVKVIDLPTEEP--KVGSTCLASGWGSTKPLDYRMWLGSAHDPLCVNIHLLSNEKCIE--------AYNEKVTDLMLCAGDLEGGKDTCKGDSGGPLICDG-----VLQGITSWG-SDPCAEPNMPAIYTKLIKFTSWIKEVMKENS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5K2-1", "uniprot_id": "KLK4_HUMAN", "id": "Q9Y5K2-1", "name": "Kallikrein-4", "aln": "MATAGNPWGWFLG----YLILGV---------------AGSLVSG------------------SCSQIINGEDCSPHSQPWQAALVM-EN-ELFCSGVLVHPQWVLSAAHCFQN--------SYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIASQCP--TAGNSCLVSGWGLLANGR------MPTVLQCVNVSVVSEEVCSK--------LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZRA7-1", "uniprot_id": "D3ZRA7_RAT", "id": "D3ZRA7-1", "name": "", "aln": "MARAGHPWKWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPN-KLYCGAVLINPQWLLTAAHCRKP--------VFRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSH-----------PGHSNDLMLIKMNRKIRASHSVKPVEITSDCP--KEGTRCMVSGWGTTSSSHN----NFPKVLQCLDITVLSEERCKN--------SYPGQIDKTMFCAG-DEAGRDSCQGDSGGPVICNG-----KLQGLVSWG-DFPCAQPNRPGVYTNLCEFVPWIKDTIHSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKQ9-1", "uniprot_id": "KLK9_HUMAN", "id": "Q9UKQ9-1", "name": "Kallikrein-9", "aln": "-----------MKLGLLCALLSL---------------LAGHGWA-------------------DTRAIGAEECRPNSQPWQAGLFHLT--RLFCGATLISDRWLLTAAHCRKP--------YLWVRLGEHHLWK-WEGPEQLFRVTDFFPHPGFNKDLS-------ANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCV--SPGMQCLISGWGAVSSPKA----LFPVTLQCANISILENKLCHW--------AYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNG-----TLAGVVSGG-AEPCSRPRRPAVYTSVCHYLDWIQEIMEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKR0-1", "uniprot_id": "KLK12_HUMAN", "id": "Q9UKR0-1", "name": "Kallikrein-12", "aln": "-----------MGLS-IFLLLCV---------------LGLSQAA-------------------TPKIFNGTECGRNSQPWQVGLFEGT--SLRCGGVLIDHRWVLTAAHCSGS--------RYWVRLGEHSLSQ-LDWTEQIRHSGFSVTHPGYLG--A-------STSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCA--TAGTECHVSGWGITNHPRN----PFPDLLQCLNLSIVSHATCHG--------VYPGRITSNMVCAGGVPG-QDACQGDSGGPLVCGG-----VLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "----------MLLLLTILQALAV---------------AIVQSQG-------------------DDKILGGYTCVQNSQPWQVALQAGPGRRFLCGGVLLSDQWVITAAHCARP--------LLHVALGKHNLRR-WEATQQVLRVVRQVPHPQYRP-----------QAHDNDLMLLKLQRKVRLGRAVRTIPVARSCA--SPGTPCRVSGWGTTASPIV----RYPTALQCVNVNIMPEQVCHR--------AYPGTITSGMVCAGVPEGGKDSCQGDSGGPLVCQG-----QLQGLVSWG-MERCAMPGYPGVYTNLCNYHSWIQRTMQSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04814-1", "uniprot_id": "TRYA_DROME", "id": "P04814-1", "name": "Trypsin alpha", "aln": "----------MLKIVILLSAVVCALG-------------GTVPEGLLP--------------QLDGRIVGGSATTISSFPWQISLQRSG--SHSCGGSIYSANIIVTAAHCLQS--------VSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNAN-----------TMVNDIAVIRLSSSLSFSSSIKAISLATYNP--ANGASAAVSGWGTQSSGSS----SIPSQLQYVNVNIVSQSQCASST-----YGYGSQIRNTMICAA--ASGKDACQGDSGGPLVSGG-----VLVGVVSWG--YGCAYSNYPGVYADVAVLRSWVVSTANSI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "-------MKWCWGPVLLIAGATVLM--------------EGLQAAQRACGQRGP-----GPPKPQE-----GNTVPGEWPWQASVRRQG--AHICSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREG-LSPGAEEVGVAALQLPRAYNHYS-----------QGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGW----DQDTS---DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFA--SSCAQEDAPVLLTNTAAHSSWLQARVQG----AAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAP-------EEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPG----MVCTSAVG--ELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEE------PE----------PEAEPGSC---------------LANISQP------------------TSC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "-------MARHLLLPLVMLVISPIP--------------GAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGG--GHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDG-PLDGAHTRAVAAIVVPANYSQVE-----------LGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPL---PLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFG--FGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWDN-ASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQG--AAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCL---RPRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: .: *.. : :::**** * : *: :::: : :. . . :** . * .* * *****::. * : . *. . : : *: ", "identical_positions": 22, "similar_positions": 33, "identity": "2.44%" }, { "cls_id": "homologset.agr.FB:FBgn0003865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9T2-1", "uniprot_id": "D4A9T2_RAT", "id": "D4A9T2-1", "name": "", "aln": "MNSHHV-VLTLASLMFLM-CLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELTHHENLVSFLETVNQPHHQNVS-VPSNNVHAPFPSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECVGPECIDYGSKTVKCMNCMF-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP52-1", "uniprot_id": "TWSG1_MOUSE", "id": "Q9EP52-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKSHYI-VLALASLTFLL-CLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQLHHQNVS-VPSNNVHAPFPSDKERMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZX9-1", "uniprot_id": "TWSG1_HUMAN", "id": "Q9GZX9-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKLHYVAVLTLAILMFLT-WLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQNVS-VPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGH0-1", "uniprot_id": "TWS1A_DANRE", "id": "Q9DGH0-1", "name": "Twisted gastrulation protein homolog 1-A", "aln": "MRPALFLCPVLISVLFLLSSLSLISGCNKALCASDVSKCLLQGLCQCRPQEGNCSCCKECMLCLSSLWEECCDCVGMCNPRSYNDSPATSKSTVEELYRPIPSLFRALTEGDAPINMMVVSFPVAEELSHHENLVSFLETLDS-QSQNIS-LPTS------SAQDDALCTVVYFDDCVSIRQCKQYCESMGGSKYRWFHNACCECIGPECLDYGSKTVKCMNCLI-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q98SR9-1", "uniprot_id": "TWS1B_DANRE", "id": "Q98SR9-1", "name": "Twisted gastrulation protein homolog 1-B", "aln": "MGSSSS--SSVVLLLLLLSSLSIALACNKALCASDVSKCLIQELCQCRPADGNCSCCKECMLCLGSLWEECCDCVGMCNPRSMSESPATGRSTVEDLFQPIPSLFRALTEGDAPTHTLVLTLPLAEELQYQHNLHNYLETLHNTQHNNTTSVPENSIHSSYHTQDK-QCTVVYFDECVSIRQCKQYCESMGGSKYRWFHNACCQCIGPECVDYGSKSVRCLNCLY-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54356-1", "uniprot_id": "TSG_DROME", "id": "P54356-1", "name": "Protein twisted gastrulation", "aln": "MQLLCYFVILFVGIAPWS-SLANDDGCNEVVCGSVVSKCLITQSCQCKLN--DCHCCKDCLNCLGELYIECCGCLDMCPKHKDVLPSLTPRSEIGDIEG-VPELFDTLTAEDDEG-WSTIRFSMRAGFKQRVQGGASGDAGNGNGNGNAG------------SAGVTLCTVIYVNSCIRANKCRQQCESMGASSYRWFHDGCCECVGENCLNYGINESRCRGCPEDQDQLLTADTVPAEAEQDLERFFGNEEIEDEWGYGEEDEFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : *. .**:.:*.* *****: ***: :* ***:*: **. *: ***.*:.** :. .. * :* : :: :*.** :** * : :.: : : : :: . * : ***:*.:.*: .:*: *****.*.*****:.**:*:* :*::** : :* .* ", "identical_positions": 63, "similar_positions": 60, "identity": "23.68%" }, { "cls_id": "homologset.agr.FB:FBgn0003866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LLL2-1", "uniprot_id": "A0ABK0LLL2_RAT", "id": "A0ABK0LLL2-1", "name": "", "aln": "-----------------------------------------------------------------------------MPRRKQQAPRRSAES---------SLKVEATDAYVPEEELKAAE---IDEEHVEDGGLSLDIQ-ESEFVCNEET----EIKEAQSYQNSPVSTATNQDAGYGSPFSEGSDQLAHFKSSTSRE----EKEEPQCPDSVSYP------------------QDSLAQIKAVYANLFSESCWSSLALDLKKS-----------------SSTTSNNDASQKESSTPTPTPPTSTASTACTTATTAITSCSTSTSHSSTTSNNSSSG---YDWHQAALAKTLQQTSSYG-----LLP---EPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNR-DKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAIT-KLVPSTKKRALQDLASPCSPEPTGMATDVALSESA--KDQKTANPYVTPNNR----YGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVV---------EEKIQSIPLPPTTHTRLPASSIKKQPDSPAGSVASEEKKEPEKEKEKEKAPPTAGDTERKIKEETEDATEKFEPT---ALYQYLREEDLDDSPKGGVDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKP-LQSAVQSVQIQPSY-ASSVKSLSSTEHNALLHSPGSLTPPP-HKSNVSAMEELVEKVTGKVSVKKE--ERPTEKE-KASPVKAISPVAKENKDLPKSEETGSKPQKKG---SDLETGKAK----KESTVDAHTPNGTEPLKAKVTN-GCSNLGIITDHSPEPSFINPLSALQSIMNTHLGKVSKPV------SPSLDPLAMLYKISNSMLDKPVYPTTPAKQADA----IDRYYYE-NSDQPIDLTKSKN------------------------------KPLVSGVADAVSSPLRESALMDISDMVKNLTGRLTPKSSTPSTVS-EKSDADG-SSFEEALDELSPVHKRKGRQSNWNPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFS--LKDLSKLPLSQIQEQQS-VSKALANKTLGP----------------LGSS----EEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYVTELEKQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTH5-1", "uniprot_id": "TSH1_MOUSE", "id": "Q5DTH5-1", "name": "Teashirt homolog 1", "aln": "-----------------------------------------------------------------------------MPRRKQQAPRR-------------------SAAYVPEEELKAAE---IDEEHAEDGGLSLDIQ-ESEFACNEET----EIKEAQSYQNSPVSTATNQDAGYGSPFSEGSDQLAHFKSSSSRE----EKEESQCPDSVSYP------------------QDSLAQIKAVYANLFSESCWSSLALDLKKS-----------------NSATSNNDASQKESSTPTPTPPTSTASTACTTATTAITSCSTSTSHSSTTSNSSSSG---YDWHQAALAKTLQQTSSYG-----LLP---EPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNR-DKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAIT-KLVPSTKKRALQDLASPCSPEPTGVATEVALSESA--KDQKTANPYVTPNNR----YGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVV---------EEKIQSIPLPPTTHTRLPASSIKKQPDSPAGSVASEEKKEPEKEKEKEKAPPAAGDAERKIKEETEDATEKFEPT---ALYQYLREEDLDDSPKGGVDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKP-LQSAVQSVQIQPSY-ASSVKSLSSTEHNALLHSPGSLTPPP-HKSNVSAMEELVEKVTGKVSIKKE--ERPTEKE-KSSPVKAISPVAKENKDLPKTEETGSKPQKKG---SDSETGKAK----KESTLDAHTPNGTEPLKAKVTN-GCGHLGIITDHSPEPSFINPLSALQSIMNTHLGKVSKPV------SPSLDPLAMLYKISNSMLDKPVYPTTPAKQADA----IDRYYYE-NSDQPIDLTKSKN------------------------------KPLVSGVADAVSSPLRESALMDISDMVKNLTGRLTPKSSTPSTVS-EKSDADG-SSFEEALDELSPVHKRKGRQSNWNPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYVSHLETHLGFS--LKDLSKLPLSQIQEQQSVVSKALTNKTLGP----------------LGSS----EEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYVTELEKQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSZ6-1", "uniprot_id": "TSH1_HUMAN", "id": "Q6ZSZ6-1", "name": "Teashirt homolog 1", "aln": "-----------------------------------------------------------------------------MPRRKQQAPRR-------------------SAAYVPEEELKAAE---IDEEHVEDDGLSLDIQ-ESEYMCNEET----EIKEAQSYQNSPVSSATNQDAGYGSPFSESSDQLAHFKGSSSRE----EKEDPQCPDSVSYP------------------QDSLAQIKAVYANLFSESCWSSLALDLKKS-----------------GSTTSTNDASQKESSAPTPTPPTCPVSTTGPTTSTPSTSCSSSTSHSSTTSTSSSSG---YDWHQAALAKTLQQTSSYG-----LLP---EPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNR-DKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAIT-KLVPSTKKRALQDLAPPCSPEPAGMAAEVALSESA--KDQKAANPYVTPNNR----YGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVV---------EEKIQSIPLPPTTHTRLPASSIKKQPDSPAGSTTSEEKKEPEKEK-----PPVAGDAE-KIKEESEDSLEKFEPS---TLYPYLREEDLDDSPKGGLDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKP-LPAAVQSVQVQPSY-AGGVKSLSSAEHNALLHSPGSLTPPP-HKSNVSAMEELVEKVTGKVNIKKE--ERPPEKE-KSSLAKAASPIAKENKDFPKTEEVSGKPQKKG---PEAETGKAK----KEGPLDVHTPNGTEPLKAKVTN-GCNNLGIIMDHSPEPSFINPLSALQSIMNTHLGKVSKPV------SPSLDPLAMLYKISNSMLDKPVYPATPVKQADA----IDRYYYE-NSDQPIDLTKSKN------------------------------KPLVSSVADSVASPLRESALMDISDMVKNLTGRLTPKSSTPSTVS-EKSDADG-SSFEEALDELSPVHKRKGRQSNWNPQHLLILQAQFASSLRETTEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFS--LKDLSKLPLNQIQEQQN-VSKVLTNKTLGP----------------LGAT----EEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYVTELEKQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DJM5-1", "uniprot_id": "TSH1_DANRE", "id": "B3DJM5-1", "name": "Teashirt homolog 1", "aln": "-----------------------------------------------------------------------------MISLILQFMLKLHILGTILSHHLFFPLCFVFSAYVPEDELKAAK---IDEEHLQDDGLSLDGQ-DAEYLCNEED----DGREQLSYQNSPLSNGTNPDAGYGSPLSDTSDHLADFKSTSSKEGQDKEEVEDMDTDAKLSL------------------QDSLAQMKAVYANLISDASWSSITKDIMKSKQVSASSINSTSSSHKGNNSVANSHASTIASSGASSSSNASASTKTNVTQSSNSTKATTLTNANNGTINGANSGGVAYDWHQAALAKTLQHTP-YH-----LMP---EPSLFSTVQLYRQNNKLYGPVFTGASKFRCKDCSAAYDTLVGLTVHMNETGHYRDDNK-DKEEDRGKKWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPMPALASKLVPSTKKRVFQDLMSPCSPDSISSTPGIPLAETAPTKDPKISNPYVTANNR----YGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTNSASKKGKQLVFDPVV---------EEKIQSIPLPPTT-TRLPAPAIKSQPDSPIHPSIMDDRKELEEEK-------FEEPEEKKIKQEKEDPSERVEKSEKLSHYKYLREEDLEESPKGGLDILKSLENTVSSAISKAQTGTPTWGGYPSIHAAYQLQGSVKS-SIPAIQSVQIQPTFNASSLKSLTS-DSSTLIHSPSSPSPPPNHKSNVLAMEELVEKVTGKIPSKKDRDEKLTERNSKHLTAELPSPVLKERKDLPKPDDLT-KPTKNGTVDKDLEHTPVREGEYKESHADNPIKNGTDALKTQVSN-GCGNLGIITDHSPEQPLVNPLSALQSIMNTHLGKASKTV------SPLLDPLAMLYKISNNMMEKPMYNPAQVKQVEP----INRYYEN-DDDQPMDLTKSKSGIGPTNNCTSTIISNSSITNST--------RPILSTLAEQVSSPLRENALMDISDMVKNLTGRLTPKSSTPSSIS-EKSDADG-CAFEDGLEDLSPIQKRKGRQSNWNPQHLLILQAQFASSLRETPDGKYIITDLGPQERVHICKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNIDSGHPLFLCSDCASQFRTPSTYINHLESHLGFS--LKDLSKLSIDLIRDQQA-VTKMITDKTFRA----------------LDLN----EEDSNSIFQCKLCNRTFVSKHAVKLHLSKTHGKSPEDHLIFVTELEKLEKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZKB9-1", "uniprot_id": "TSH3_RAT", "id": "D3ZKB9-1", "name": "Teashirt homolog 3", "aln": "-----------------------------------------------------------------------------------------------------------MAAYVS-DELKAAA---LVEDDIEPEEQVADGEPSAKYMCPEKE----LSKACPSYQNSPAAEFSSHEMDSESHISETSDRMADFESSSIKNEEE--TKEVQVPLEDTT------------------VSDSLEQMKAVYNNFLSNSYWSNLNLNLHQP-------------------------------------------------SSEN--NGGGSSSSSSSSSSSCGSGS--FDWHQSAMAKTLQQVSQN-----RMLP---EPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNH-ETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPAARKKPSLELELPSSPDSTGGTPKATLSDAS-DALQKNSNPYITPNNR----YGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIMETPVTPTITTLLD--EKVQSVPLAATTFTSP-----SNTPASVSPKLTVEIKKEVDKEK-------AVLDEKPKEKEK---ASEEEEKYDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTK---TQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPDSKL-SPPKRATPSPCSSEQSEPIKMEASSG--SGFKS--QENSPSPPRDVCKEASPSAEPVENGKELVKPLSGGSLSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPS------LPALDPMSMLFKMSNSLAEKAAVATPPPLQAKK-AEHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSGLLSPTSTSPATSS--STVTTAKTS-AVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSIS-EKSDIDG-ATLEEA-EESTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFR--LRDLSKLSTEQINNQIA-QTKSPSEKMVTS-----------------SP-----EEDLGTTYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLFVSELEKQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGV9-1", "uniprot_id": "TSH3_MOUSE", "id": "Q8CGV9-1", "name": "Teashirt homolog 3", "aln": "-----------------------------------------------------------------------------MPRRKQQAPRR-------------------AAAYVS-DELKAAA---LVEDDVEPEEQAADGEPSAKYMCPEKE----LSKACPSYQNSPAAEFSSHEMDSESHISETSDRMADFESSSIKNEEE--TKEVQVPLEDTT------------------VSDSLEQMKAVYNNFLSNSYWSNLNLNLHQP-------------------------------------------------SSEN--NGG-SSSSSSSSSSSCGSGS--FDWHQSAMAKTLQQVSQN-----RMLP---EPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNH-ETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPAARKKPSLELELPSSPDSTGGTPKATLSDAS-DALQKNSNPYITPNNR----YGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIMETPVTPTITTLLD--EKVQSVPLAATTFTSP-----SNTPASVSPKLAVEIKKEVDKEK-------AVPDEKPKEREK---PSEEEEKYDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTK---TQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPEGKL-SPPKRATPSPCSSEQSEPIKMEASSD--GSFKS--QENSPSPPRDACKEASPSAEPVENGKELVKPLSGG-LSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPS------LPALDPMSMLFKMSNSLAEKAAVATPPPLQAKK-AEHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSGLLSPTSTSPATSS--STVTTAKTS-AVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSIS-EKSDIDG-ATLEEA-EESTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFR--LRDLSKLSTEQINNQIA-QTKSPSEKLVTS-----------------SP-----EEDLGTTYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLFVSELEKQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HK5-1", "uniprot_id": "TSH3_HUMAN", "id": "Q63HK5-1", "name": "Teashirt homolog 3", "aln": "-----------------------------------------------------------------------------MPRRKQQAPRR-------------------AAAYVS-EELKAAA---LVDEGLDPEEHTADGEPSAKYMCPEKE----LARACPSYQNSPAAEFSCHEMDSESHISETSDRMADFESGSIKNEEE--TKEVTVPLEDTT------------------VSDSLEQMKAVYNNFLSNSYWSNLNLNLHQP-------------------------------------------------SSEK--NNG-SSSSSSSSSSSCGSGS--FDWHQSAMAKTLQQVSQS-----RMLP---EPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNH-ETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPATRKKASLELELPSSPDSTGGTPKATISDTN-DALQKNSNPYITPNNR----YGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIVETPVTPTITTLLD--EKVQSVPLAATTFTSP-----SNTPASISPKLNVEVKKEVDKEK-------AVTDEKPKQKDK---PGEEEEKCDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTK---NQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPDGKL-SPPKRATPSPCSSEVGEPIKMEASSD--GGFRS--QENSPSPPRDGCKDGSPLAEPVENGKELVKPLASS-LSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPS------LPALDPMSMLFKMSNSLAEKAAVATPPPLQSKK-ADHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSVLLSPTSTAPATSS--STVTTAKTS-AVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSIS-EKSDIDG-ATLEEA-EESTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFR--LRDLSKLSTEQINSQIA-QTKSPSEKMVTS-----------------SP-----EEDLGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLYVSELEKQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7C9-1", "uniprot_id": "A0ACD6B7C9_DANRE", "id": "A0ACD6B7C9-1", "name": "", "aln": "-----------------------------------------------------------------------------MPRRKQQAPRR-------------------SAAYVP-EELKEAA---LLDEDVEGEDSALEEEPAMKYVCQDKDL---LLKDRPGFHDSPPADFSSHEMDSESHLSESSDRMSDFESASVKNEEDSSAKEPLTSLSSTSSMMMTTTATPSSEEATPLGPDSLEQMKAIYTSFLTNSYWSSLNLNLSQQ-------------------------------------------------PPEKPPRSHSSSSSSSSSSSSCGSGG--YDWHQTAVAKTLQNVSQNQS---RLLHPASEPNLFSTVQLYRQSTKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNH-ETDSEGTKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIISSARKRAPIELELPSSPDSNGGTPKPSLSDPN-DLLQKTPNPYITPNNR----YGHQNGASYAWQFESRKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAIKKGKPIMESMSTTAPNPILTNEDKVQSVPLAATAFSPPPP---APPPPSISPAIMPMEIKKEEKEV-------ECTRETNNNKDKKAAESETDEKFEVSSKYPYLTEEDLEESPKGGFDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNIMKLSLRNSGKSSPLKYMFSGEELLSPTK---SQPLISPPSCQTSPFPKNNFHAMEELVKKVTEKVAKVEEKMRDPGARS-SPLRRTTPSPCSSDAGESARGESPKERRGAKTP--ETNGGGITHKESNGDALTKESLENGTDHVVKTPVSTLCSSTAIITDHPPEQPFVNPLSALQSVMNVHLGKAAKPA------LPSLDPMSMLFKMSNSLAEKAAVAASTPSQTKKTNDHLDRYFYHINNDQPIDLTKGKSDKSNSLGSAALSSSTSTPTSISPSSTITMAKASSAVASFMSNSPLRENALSDISDMLRNLTENHASKSSTPTSLS-ERSDIDG-STPEES-EEISPAQKRKGRQSNWNPQHLLILQAQFASSLRQTGDGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDSGHPVFFCSDCASQIRSPSTYVSHLESHLGFR--LRDLAKLSGEHLVSQISRHTKGLSEKLLSAQAHSLAHTIANPSPHSLSPSPSPDEEANGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLMYVSELEKP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0KYY4-1", "uniprot_id": "A0ABK0KYY4_RAT", "id": "A0ABK0KYY4-1", "name": "", "aln": "MLFFLNYVAPCRPGPFFLDKESTSWNIGEDIYEPAERRSLTHIGKVHIIPTSMLLPSPAPPPTPLFCSTERLEGKGILETTQLPTSKL-------------------QGRYAQEEVLKEEEEIKEEEEEDEDSGSVAQHQGSNDTGTDEELETGPEQKGYFSCQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCSRDAPD--KKANPHAKLPSEP------------------HNCMDKMTAVYANILSDSYWSGLGLGFKLS----------------------------------------------------------NSERRNCDTRNGSSKND--FDWHQDALSKSLQQNLPSR-----SVS---KPSLFSSVQLYRQNSKMCGSVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNR-KKDKLRPTSYSKPRKRAFQDMD-KDDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVAPAKKR-VFDVNRPCSPDSTTGS----LADSF--SSQKSANLQLPSNSR----YGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLA---------VEKMQSLSESPNSESLAPKP--SSNSPSESTASATELKKESKKEK-------GEINEDEQGVKNEEYEDALQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPMAMGSQILQIRPNLANKLRPIAPKWKGMPLGPVPASLALYTQVKKEAEDKEEVMKQCRKESPHEEATSFSQPESE-SFSKIEPPSESRKAESCPLKEEEKLLKE----------------------------KPEPLEPVSSLTNG------CAVANHSPALPSINPLSALQSVLNNHLGKATEPLRSPSCSSPNSSTIPMFHKSSLGVVDKPVISPTSTRPAAS----VSRHYLFENTDQPIDLTKSKS------------------------------KRAESSQAQSCTSPPQKHALCDIADMVKVLPKATTPKPAASSRVPPVKLEIDV-RRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQ--MKDMTRMAADQQSKVEQEISRVSSAQRSPE-----------------TIAD---EEDTDSKFKCKLCSRTFVSKHAVKLHLSKTHSKSPEHHAQFVTDVDEE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FE9-1", "uniprot_id": "TSH2_MOUSE", "id": "Q68FE9-1", "name": "Teashirt homolog 2", "aln": "-----------------------------------------------------------------------------MPRRKQQAPKR-------------------AAGYAQEEVLKEEEEIKEEEEEEEDSGSVAQHQSSNDTGTDEELETGPEQKGYFSCQNSPGSHLSNQDAENESLLSDASDQVSDVKSVCGRDVSD--KKANTHPKLPSEP------------------HNCMDKMTAVYANILSDSYWSGLGLGFKLS----------------------------------------------------------NSERRNCDTRNSSGKND--FDWHQDALSKSLQQNLPSR-----SVS---KPSLFSSVQLYRQSSKLCGSVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNR-KKDKLRPTSYSKPRKRAFQDMD-KEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKR-VFDVNRPCSPDSTTGS----LADSF--SSQKSANLQLPSNSR----YGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLA---------VEKMQSLSETPNSESLAPKP--SSNSPSECTASTTELKKESKKEK-------GEGIEDEQGVKSEDYEDSLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPMAMGSQILQIRPNLANKLRPIAPKWKGMPLGPVPTSLALYTQVKKETEDKDEVVKQCGKESPHEEATSFSQPEGE-SFSKIEPPSESRKAEPCPLKEEEKPQKE----------------------------KPEPLEPVSSLTNG------CAPANHTPALPSINPLSALQSVLNNHLGKATEPLRSPSCSSPNSSTSPVFHKSSLHVVDKPVISPTSTRPAAS----VARHYLFENTDQPIDLTKSKS------------------------------KRAESSQAQSCTSPPQKHALCDIADMVKVLPKATTPKPAASSRVPPMKLEIDV-RRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQ--MKDMTRMAADQQSKVEQEISRVSSAQRSPE-----------------TIAG---EEDTDSKFKCKLCRRTFVSKHAVKLHLSKTHSKSPEHHSQFVADVDEE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRE2-1", "uniprot_id": "TSH2_HUMAN", "id": "Q9NRE2-1", "name": "Teashirt homolog 2", "aln": "-----------------------------------------------------------------------------MPRRKQQAPKR-------------------AAGYAQEEQLKEEEEIKEEEEE-EDSGSVAQLQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASD--KKAHTHVRLPNEA------------------HNCMDKMTAVYANILSDSYWSGLGLGFKLS----------------------------------------------------------NSERRNCDTRNGSNKSD--FDWHQDALSKSLQQNLPSR-----SVS---KPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNR-KKDKLRPTSYSKPRKRAFQDMD-KEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKR-VFDVNRPCSPDSTTGS----FADSF--SSQKNANLQLSSNNR----YGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLA---------VEKMQSLSEAPNSDSLAPKP--SSNSASDCTASTTELKKESKKERP------EETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSFSHSEGD-SFRKSETPPEAKKTELGPLKEEEKLMKEGSEKE-----------------------KPQPLEPTSALSNG------CALANHAPALPCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTR-SAS----VSRRYLFENSDQPIDLTKSKS------------------------------KKAESSQAQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDV-RRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQ--MKDMTRLSVDQQSKVEQEISRVSSAQRSPE-----------------TIAA---EEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDVDEE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22265-1", "uniprot_id": "TSH_DROME", "id": "P22265-1", "name": "Protein teashirt", "aln": "-------------------------------------------------------------------------------------------------------------------MLHEALMLEIYRQALNAGALPTARPRSTESANSSER--------------CPSHDSNSSEHGGGAGSGGVGHRLDAAALSTGVMPGE--GPTTLHSSFPAVP-------------------QSLPSQPPSMEAYLHMVAAAAQQYGFPLA----------------------------------------------------------AAAAAGAGPRLPLPLAN-----EAAAPFKLPPQASPTASSNNS-------EALDFRTNLYGRAESAEPPASEGEE----EEFDDGANNPLDLSVGTRKRGHESEPQLGHIQVKKMFKSDSPPANSVASPSASQLLPGVNPYLAAVAAANIFRAGQFPDWNSKNDLVVDPLEKMSDIVKGGASGMGTKEKMHSSKATTPQAASQPPKSPVQPTPNQNSESGGGSGGGAAGSGAVTKARHNIWQSHWQNKGVASSVFRCVWCKQSFPTLEALTTHMKDS----------------------------------KHCGVNVPPFGNLPSNNPQPQHHHPTPPPPPQNHNLRKHSSGS--------ASNHSPSANVKNAFQYRGDPPTPLPRKLVRGQNVWLGKGVEQAMQILKCMR----CGESFRSLGEMTKHMQETQHYTNILSQEQSISIKSGNANANSDAKESHNSLSSEES-------RTLSAVLTCKVCDKAFNSLGDLSNHMAKNNHYAEPLLQSAGARK---------RPAPKKREKSLPVRKLLEMKGGSGT-----------------------TQEDHSNEKTSVQG--------KPGLGPGGGDKNDAALFAERMRQYITGVKAPEE----IAKVAAAQLLAKNKSPELVEQKNGGSAKAAGASSVLSAIEQMFTTSFDTPPRHASLPASSPS---------------------------NSSTKNTSPVASSILKRLGIDETVDYNKPLIDTNDPYYQHYRYTSSERSGSECSAEARPRLDAPTPEKQQQGGGHDEESSKPAIKQEREAESKPVKMEIKSEFVDEPNE----AEETSKMEAAVVNGSATNNNNNIVERSSPKTPSSAASPQTRLLPPRSPAESQRSVTPKSPASSHKSYDGSSEGTKKFPSDSLNALSSMFDSLGSS-------------------------------GAGANSRAKLAAAAAAGGSESPENLTAGGNSLAALRQFCVKKEKTA---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : . .: .* . : : . ..:: :.: . . : : .: . . . * * : * .:** : . . * . .: . . :. : *:* .: ** : : . : ..* .:. . . .: * : . : : :: .. ::*: * * :. : . .: . . :*:. . . . . . . . . :* . *: :. :.:::*: * .*. **: **:** : * .: .. : :: .. . . : * .. : . :***.:. . . . * : : * : * . . . .. : :. : : . : . . . * * : : . :. :: . . . : : . : :: .. : : : * . : . . : * :. .: : * : * . . : : . . :. ::::* : :..: * * : * * . : * : * : . : :. :.:. :* : :: . ...* .. . :. : ..:: : . * . .:* .: .. ::. . : .: :.**. : .. :*: .. . : * . . ", "identical_positions": 58, "similar_positions": 254, "identity": "4.33%" }, { "cls_id": "homologset.agr.FB:FBgn0003884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71U36-1", "uniprot_id": "TBA1A_HUMAN", "id": "Q71U36-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68370-1", "uniprot_id": "TBA1A_RAT", "id": "P68370-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68369-1", "uniprot_id": "TBA1A_MOUSE", "id": "P68369-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05213-1", "uniprot_id": "TBA1B_MOUSE", "id": "P05213-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68363-1", "uniprot_id": "TBA1B_HUMAN", "id": "P68363-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P9V9-1", "uniprot_id": "TBA1B_RAT", "id": "Q6P9V9-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68373-1", "uniprot_id": "TBA1C_MOUSE", "id": "P68373-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGD--DEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYZ1-1", "uniprot_id": "TBA1C_RAT", "id": "Q6AYZ1-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLARVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGD--DEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQE3-1", "uniprot_id": "TBA1C_HUMAN", "id": "Q9BQE3-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGE--DEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A516-1", "uniprot_id": "B8A516_DANRE", "id": "B8A516-1", "name": "Tubulin alpha chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLDRVRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGAESVEGE--DEGEEY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05214-1", "uniprot_id": "TBA3_MOUSE", "id": "P05214-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DPH7-1", "uniprot_id": "TBA3C_HUMAN", "id": "P0DPH7-1", "name": "Tubulin alpha-3C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DPH8-1", "uniprot_id": "TBA3D_HUMAN", "id": "P0DPH8-1", "name": "Tubulin alpha-3D chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FR8-1", "uniprot_id": "TBA3_RAT", "id": "Q68FR8-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PEY2-1", "uniprot_id": "TBA3E_HUMAN", "id": "Q6PEY2-1", "name": "Tubulin alpha-3E chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSEAREDLAALEKDCEEVGVDSVEAEA-EEGEAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06603-1", "uniprot_id": "TBA1_DROME", "id": "P06603-1", "name": "Tubulin alpha-1 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEG-EGAEEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6AY56-1", "uniprot_id": "TBA8_RAT", "id": "Q6AY56-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFGTQASKI-NDDDSFTTFFSETGNGKHVPRAVMVDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIVSAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEE--NEGEEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ2-1", "uniprot_id": "TBA8_MOUSE", "id": "Q9JJZ2-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFGTQASKI-NDDDSFTTFFSETGNGKHVPRAVMVDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEE--NEGEEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY65-1", "uniprot_id": "TBA8_HUMAN", "id": "Q9NY65-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKI-NDDDSFTTFFSETGNGKHVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEE--NEGEEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09734-1", "uniprot_id": "TBA3_YEAST", "id": "P09734-1", "name": "Tubulin alpha-3 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEE-----F--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09733-1", "uniprot_id": "TBA1_YEAST", "id": "P09733-1", "name": "Tubulin alpha-1 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEE-----EEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **::***** *********:.*****: ** : : ..::.*.*** *** **.****: :****.*:**** * :::********.******.********:*:* :. * :*:**::* * ******. **:*******: ***:*.** :*.*******::*****:**:******::*********:**:**********:*:***.* **:::*** **.*::**:********:*****.****************.:*:*::* .:* **. :*:***.:**** .******* .***** *:*******.:**: *: :*.*:::*:*********:** *:**:. *..:** *:**********::*:** *: :******** ****************:*****:****:* *** :* : ", "identical_positions": 296, "similar_positions": 101, "identity": "65.49%" }, { "cls_id": "homologset.agr.FB:FBgn0003885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71U36-1", "uniprot_id": "TBA1A_HUMAN", "id": "Q71U36-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68370-1", "uniprot_id": "TBA1A_RAT", "id": "P68370-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68369-1", "uniprot_id": "TBA1A_MOUSE", "id": "P68369-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05213-1", "uniprot_id": "TBA1B_MOUSE", "id": "P05213-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68363-1", "uniprot_id": "TBA1B_HUMAN", "id": "P68363-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P9V9-1", "uniprot_id": "TBA1B_RAT", "id": "Q6P9V9-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68373-1", "uniprot_id": "TBA1C_MOUSE", "id": "P68373-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGD--DEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYZ1-1", "uniprot_id": "TBA1C_RAT", "id": "Q6AYZ1-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLARVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGD--DEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQE3-1", "uniprot_id": "TBA1C_HUMAN", "id": "Q9BQE3-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGE--DEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A516-1", "uniprot_id": "B8A516_DANRE", "id": "B8A516-1", "name": "Tubulin alpha chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLDRVRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGAESVEGE--DEGEEY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05214-1", "uniprot_id": "TBA3_MOUSE", "id": "P05214-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DPH7-1", "uniprot_id": "TBA3C_HUMAN", "id": "P0DPH7-1", "name": "Tubulin alpha-3C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DPH8-1", "uniprot_id": "TBA3D_HUMAN", "id": "P0DPH8-1", "name": "Tubulin alpha-3D chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FR8-1", "uniprot_id": "TBA3_RAT", "id": "Q68FR8-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06605-1", "uniprot_id": "TBA3_DROME", "id": "P06605-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEG-EGAEEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6AY56-1", "uniprot_id": "TBA8_RAT", "id": "Q6AY56-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFGTQASKI-NDDDSFTTFFSETGNGKHVPRAVMVDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIVSAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEE--NEGEEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJZ2-1", "uniprot_id": "TBA8_MOUSE", "id": "Q9JJZ2-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFGTQASKI-NDDDSFTTFFSETGNGKHVPRAVMVDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEE--NEGEEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY65-1", "uniprot_id": "TBA8_HUMAN", "id": "Q9NY65-1", "name": "Tubulin alpha-8 chain", "aln": "MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKI-NDDDSFTTFFSETGNGKHVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEE--NEGEEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09734-1", "uniprot_id": "TBA3_YEAST", "id": "P09734-1", "name": "Tubulin alpha-3 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEE-----F--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09733-1", "uniprot_id": "TBA1_YEAST", "id": "P09733-1", "name": "Tubulin alpha-1 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEE-----EEF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **::***** *********:.*****: ** : : ..::.*.*** *** **.****: :****.*:**** * :::********.***************:*:* :. * :*:**::* * ******. **:*******: ***:*.** :*********::*****:**:******::*********:**:**********:*:***.* **:::*** **.*::**:********:*****.****************.:*:*::* .:* **. :*:***.:**** .**** ** .***** *:*******.:**: *: :*.*:::*:*********:** *:**:. *..:** *:**********::*:** *:*:*************************:*****:****:** *** :* : ", "identical_positions": 300, "similar_positions": 99, "identity": "66.37%" }, { "cls_id": "homologset.agr.FB:FBgn0003886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68363-1", "uniprot_id": "TBA1B_HUMAN", "id": "P68363-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P9V9-1", "uniprot_id": "TBA1B_RAT", "id": "Q6P9V9-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05213-1", "uniprot_id": "TBA1B_MOUSE", "id": "P05213-1", "name": "Tubulin alpha-1B chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68369-1", "uniprot_id": "TBA1A_MOUSE", "id": "P68369-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68370-1", "uniprot_id": "TBA1A_RAT", "id": "P68370-1", "name": "Tubulin alpha-1A chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68373-1", "uniprot_id": "TBA1C_MOUSE", "id": "P68373-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGD--DEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYZ1-1", "uniprot_id": "TBA1C_RAT", "id": "Q6AYZ1-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLARVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGD--DEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQE3-1", "uniprot_id": "TBA1C_HUMAN", "id": "Q9BQE3-1", "name": "Tubulin alpha-1C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGE--DEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A516-1", "uniprot_id": "B8A516_DANRE", "id": "B8A516-1", "name": "Tubulin alpha chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKELIDLVLDRVRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGAESVEGE--DEGEEY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05214-1", "uniprot_id": "TBA3_MOUSE", "id": "P05214-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DPH7-1", "uniprot_id": "TBA3C_HUMAN", "id": "P0DPH7-1", "name": "Tubulin alpha-3C chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DPH8-1", "uniprot_id": "TBA3D_HUMAN", "id": "P0DPH8-1", "name": "Tubulin alpha-3D chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FR8-1", "uniprot_id": "TBA3_RAT", "id": "Q68FR8-1", "name": "Tubulin alpha-3 chain", "aln": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG-GGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEA-EEGEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06604-1", "uniprot_id": "TBA2_DROME", "id": "P06604-1", "name": "Tubulin alpha-2 chain", "aln": "MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGHMPSDKTVG-GGDDSFSTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYMNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISVEKAYHEQLTVAEITNACFEPANQMVKCDPRRGKYMACCMLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFAEAREDLAALEKDYEEVGIDSTTELG--EDEEY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09734-1", "uniprot_id": "TBA3_YEAST", "id": "P09734-1", "name": "Tubulin alpha-3 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEF-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09733-1", "uniprot_id": "TBA1_YEAST", "id": "P09733-1", "name": "Tubulin alpha-1 chain", "aln": "MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEEEF-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **:::**** **********.*****: **:: .. : **::.*.*** *** **.****::*****.*:****.* :::********.***************:*:*::. * :*:**::* * ******. **:*******: ***:*.** :*********::*****:**:******::*********:**:**********:*:***.* **:: *** **.*::**:********:*****.****************.:*:*::* .:* **. :*:*********.******** ***** *:*******.:**: *: :*.*:::*:*********:** *:**:. *..:** *:**********::*:** *:*:*************************:*****:****:** *** :* ", "identical_positions": 307, "similar_positions": 97, "identity": "67.92%" }, { "cls_id": "homologset.agr.FB:FBgn0003889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13885-1", "uniprot_id": "TBB2A_HUMAN", "id": "Q13885-1", "name": "Tubulin beta-2A chain", "aln": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE--GEDEA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TMM9-1", "uniprot_id": "TBB2A_MOUSE", "id": "Q7TMM9-1", "name": "Tubulin beta-2A chain", "aln": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE--GEDEA----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P85108-1", "uniprot_id": "TBB2A_RAT", "id": "P85108-1", "name": "Tubulin beta-2A chain", "aln": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE--GEDEA----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWF2-1", "uniprot_id": "TBB2B_MOUSE", "id": "Q9CWF2-1", "name": "Tubulin beta-2B chain", "aln": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE--GEDEA----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVA1-1", "uniprot_id": "TBB2B_HUMAN", "id": "Q9BVA1-1", "name": "Tubulin beta-2B chain", "aln": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE--GEDEA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61857-1", "uniprot_id": "TBB2_DROME", "id": "P61857-1", "name": "Tubulin beta-2 chain", "aln": "MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDLQLERINVYYNEATGAKYVPRAILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEEGGGDE-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NNZ2-1", "uniprot_id": "TBB8B_HUMAN", "id": "A6NNZ2-1", "name": "Tubulin beta 8B", "aln": "MREIVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYVPRAVLVDLEPGTMDSVHSGPFGQVFRPDNFISGQCGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGCYLTVAAIFRGRMPMREVDEQMFNIQDKNSSYFADWFPDNVKTAVCDIPPRGLKMSATFIGNNAAIQELFTCVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE----EEDEEYAEEEVA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3ZCM7-1", "uniprot_id": "TBB8_HUMAN", "id": "Q3ZCM7-1", "name": "Tubulin beta-8 chain", "aln": "MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGGRYVPRAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRGRMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGLKMSATFIGNNTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE----EEDEEYAEEEVA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02557-1", "uniprot_id": "TBB_YEAST", "id": "P02557-1", "name": "Tubulin beta chain", "aln": "MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQEATVEDDEEVDENGDFGAPQNQDEPITENFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: . ********. ***.*..** :* *:*:*...:* **:**:.:**:. ::***:: *******:*:*:...:*::*****:: **..*** ****:******* :**:**:*:*:*.**.*****:****************:******:***:: ***::****.*****************:*::***:.********** :**** *:*****:***:.******.**:*****:********:********** *:****: ***.:*:***.********:******.***:* ***.**:***::.::**:::* ::*.***.:*.:*:*:* :****.:.*:**.*:****.*.::*****. :.:**:***:*********.*****:**:*****************:**.:: :*: . : ", "identical_positions": 292, "similar_positions": 122, "identity": "63.89%" }, { "cls_id": "homologset.agr.FB:FBgn0003891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXQ5-1", "uniprot_id": "D3ZXQ5_RAT", "id": "D3ZXQ5-1", "name": "Tudor domain-containing protein 6", "aln": "-----MSSTPGLPTPGASLALRVSFVDVHPEVIPVQLWGLVG-QRREEYVRLSREIQEAAATRG----PWALGGASASPGELCLVQVGL-------MWHRCRVVSRQAQ----DSRVFLLDEGRTITAGAGSLAPGRS--------------------------EFFHLPSEVLGCVLAGLVPAGGGGAGGGEPQHWSPNAVDFLSNLQ--------------------------------------------------------GKEVHGRVLDVLLLHRLVLLEVPVVSQQMEELGLARHVPDS---LFCSLLKRYLTAAGLGS-SGAPVLP----------------------------RAAPKQEHPGLDYFYPQLQLGVTEPVVVTQVCHPHRIHCQLRSLSQEIHRLSESMAQVYRAPTGTEDED--------------------SGSATWEEREESPDKPGSPCASCGL-DGQWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDCGRGWSRSQVGDLKALILGQAVNAKIEFYCSFEHMYYVTLYGEDGIN----LNSAFGVQSCCLADRFLQS-----------------------------------------QGIEEEEDEDEDEMEAAFQSQSPAEEMEEEVSLPSLRSIRLKMNTFYDAQVEFVKSPSEFWIRLRKHKNTFSKLTKRMCSFYSSASK-------LDGVILKPEPDDLCCVKWKENG-YYRAMVTRLDSKSVDVFLVDRGNSEN-----------------------VDWCDVRMLLPQFRQLPILALKCTLADIWPLGKTWSQEAISFFKKTVLHKELVVHILDKQDRQYVIEILDE-----------------------------------SRTGEENISKVIAQAGYAKFQEFETKENIRLSAHSPGHVSGHFIAESSKIPSVKKVEGDQKAKNDNKTLSDPEALA-TVSLSNISTGQTAQDKEKVTSDPTLLMLNLLKTK-------------------------PDCCGKGELEVGSTVEVKVSHIENPGSFWCQLMRNAQGFRTLMCDIEDYCKS-EPSPY--EGDTRACLAKRTANGRWSRALISGAQSLEHVRVVFVDYGDKDVVSMKDILSVSDVFFKVRAQAFRCSLYNLI----------------------------QPTGENPFVWDERAIQAFTGFIDNAWQNNLELKCTIFALASRHEEECFNV----------------VDLLTPFQSACHFLVEKRLARPVKL-QKPLEPSVQLHSYYYSTHDLKIGSEE---------------------------LVYITHADDPWTFYCQLARNTNILEQLSYHIMQL--SKVLLNLRTSTLVPGTLCLAKYTDGNWYRGIIIEKE-PSK---VFFVDFGNTYVAS-DHLLPIPRDAYDVLLLPMQAVKCSLSDIP-HHIPEEVTAWFQETVLDKSLKALVVAKDPDGRLIIELYDESVQINASINEKLGLLGYKNRTRRKDKENEIILRETETLQDKAEIMKPSPTDYLGKSGDSKAHGVEIMGESCKPKLSPACKELK-----YLQGSGKAHLVTPYQDSMGNKNDGGFLLTREKREDMFASSPMSATKLESALPERRMGEASGKDLPPKFCEFPQKTIAPGFKTSVYVSHINDLSDFYIQLIEDETEINRLSERLNDVRTRPQYH-TGPPWQSGDVICAVFPEDNLWYRAVVLEQQHNDLLSVQFIDYGNMSVVHTNRTGRLGPIDAVLPALCLHCSLRG--IVVPDIVGTKEMVA-----------YFSQRTDEAQIRCEFVKFQG-TWEVILADEHGIIAEDIINRFPFNGKSQ---AGLTTQSMKGDCSKTALKTNMDTSVFLNWYNPKMKLIKAYATVIDGPEYFWCQFADSEKLQYVETEVQNAAKQLADRKSCTQCPQIGDP------------------CIVRYREDGHYYRALITNICDDHLASVRLVDFGNVEDCVDTNALWSIPSELLLVPMQAFPCCLSGFTVSGGVCPQEGNDYFYDIVTEDVLEITILEIKR---------DVCDIPLAVVELRSK--GENINEKMKKYAKTGTPKSGLYSEKHGAERKGGLSSP--DLGLKKPSHKIAQEKTFYMEARASELSERFEKDLN-IETRPSKFYERSPRNIFNAFEHSCQGKMGSQRLEGGMDYHFVDRVK-----YDDTYLMTGFNPILAHAS---EPKELLELNSLEVPLSPD--DECKEFLELESIDLQHSPAGEEDKEELGLGSPMAPLSPGCQAGATLEPFMVQLPLDCEAEKQLE-LELPTPQLSLEDSISPLSATVS--QNMPESRSAEDERKSSCVGSSDDDDDHSASPLPHHGKGGDSPAHDEMNLSEEEFPQFENRDSAALLAPLFSEEEARGGRKGRSEVPA---VELQNTYTLKG-----------FSVGSKCVVWSSLRNTWSKCEILALAEEGTRVLNLANGVEETVSPENVWNGIPKVDKRPSEAAFQTVGKDLPFTPSDDTTIEGFFCSVSEEECGGDAD---SAKLNV---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61407-1", "uniprot_id": "TDRD6_MOUSE", "id": "P61407-1", "name": "Tudor domain-containing protein 6", "aln": "-----MSSTPGLPTPGASLALRVSFVDVHPEVIPVQLWGLVG-QRREEYVRLSREIQEAAATRG----PWALGGASASPGELCLVQVGL-------MWHRCRVVSRQAQ----DSRVFLLDEGRTITAGAGSLAPGRS--------------------------EFFHLPSEVLGCVLAGLVPAGGGGTGGGEPQQWSPRAVDFLSNLQ--------------------------------------------------------GKEVHGRVLDVLLLHRLVLLEVPVVSQQMEELGLARQVPDS---LFCSLLKRYLTAAGQGS-SGAPVLP----------------------------RAAPKQEHPGLDYFYPQLQLGVTEPVVVTQVCHPHRIHCQLRSLSQEIHRLSESMAQVYRAPVGTDDED--------------------SGSATWEEREESPDKPGSPCASCGL-DGQWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDCGRGWSRSQVGDLKALILGQAVNAKIEFYCSFEHMYYVTLYGEDGIN----LNSAFGVQSCCLADWFLQS-----------------------------------------QGIEEEEEEDEDEVEAAFQSQSPAEEMEAEVSLPSLRSIRLKMNTFYDAQVEFVKSPSEFWIRLRKHKNTFSKLTKRMCSFYSSASK-------LDGVILRPEPDDLCCVKWKENG-YYRATVTRLDSKSVDVFLVDRGNSEN-----------------------VDWCDVRMLLPQFRQLPILALKCTLADIWPLGKTWSQEATSFFKKTVLHKELVVHVLDKQDHQYVIEILDE-----------------------------------SRMGEENISKVIAQAGFAKFQEFETKENIRLSAHSPGHVSGHFMAEPSKITSAKKAEGDQRAKKDNKTLSVSEALADTVSLSNLST---AQDTEKVTSDPSLLMLNFLKTK-------------------------PDCCGKGELEVGSTVEVKVSHIENPGSFWCQLMRNAQGFRTLMCDIEDYCKSSEPSPY--EGDTRVCLAKRTASGRWSRALISGAHSLEHVRVVFVDYGDRDVVSTKDILSVSDVFFQVRAQAFRCSLYNLI----------------------------QPMGENPFVWDEKAVQAFSGFIDSARQNNLELKCTVFALASRHEEEWFNV----------------VDLLTPFQSACRFLVEKRLARPVKH-QKPLEPSVQLHSYYYSTHDLKIGSEE---------------------------LVYVTHADDPWTFYCQLARNINVLEQLSYNIMQL--SKALLNLKASTLAPGTLCLARYTDGNWYRGIIIEKE-PSK---VFFVDFGNTYIAV-DHLLPIPRDAHDVLLLPMQALKCSLSDIP-HHIPEEVTAWFQETVLDKSLKALVVAKDPDGRLIIELYDDSVQINASINEKLGLLGYKNRTRRKEKENEIILHETKALEDKKESVKPSLADYLGKPGESKAHSIEIMGESCKPKMGPACKELR-----YLQGSAKANLVPPYQDSVGNKNDGGFPLTREKKEDIFASSPMSGTKLDSALPERRMGEPSGRDLPPKFCEFPQKTIAPGFKTSVYVSHINDLSDFYIQLIEDEAEINNLSERLNDVRTRPQYH-TGPQWQSGDVICAVFPEDNLWYRALVMEQQPNGLLSVQFIDYGNMSVVHTNRTGRLGPVDAVLPALCLHCSLWG--LSVP---VCKEMVS-----------YFSQRTDEAQIRCEFVKFQG-TWEVILADEHGVIAEDMISRFPCNGNSQ---AGLTTQTMKGDCLKIANKPNTDTSVLLNWYNPKAKLIKAYATVIDGPEYFWCQFADSEKLQYLETEVQSAGKQLSDRRSCTQCPQIGDP------------------CIVRYREDGHYYRALITNICDGELASVRLVDFGNAEDCVDAKELWSIPSELLLVPMQAFPCCLAGFSVSGGVCPQEGNDYFYDIVTEDVLDITILEIKR---------DVCNIPLAIVELRSK--GENINEKMKKYAKTGVPKNDLSSEKRGPERKGSLASP--DLGLKKPSHKIAQDKTFYGEARASELSERLEKDLN-IETKTSKFYERSTRSIFNAFENSCKGKMGSERLEGSMDYHFVDRAK-----FDNNYLITGFNPILAHAS---EPKELLELSSLEVPLSADNDDECKEFLELESIELQHSPAGEEEKEELGLGSPMAPLSPGCQAGATLESFMMQLPLDCEAEKQLE-LKLPTPQLSLEDSISPLSAAVS--QDIQGSRCSEDERKAGYMGSSDD--DHSRSPLLQHGKGGNSPAHDGRNLSEEEFPQFESRDSAALLAPLFSEEEAREGRKCGSMVP----AQLQSTYTLKG-----------FSVGSKCVVWSSLRNTWSKCEILELAEEGTRVLNLSNGVEETVSPENVWNGIPKVDKRPSEAVFQTVGKDLPFMPSDDATTKGFSSVSEEEACGGDADSLSTAKLNI---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60522-1", "uniprot_id": "TDRD6_HUMAN", "id": "O60522-1", "name": "Tudor domain-containing protein 6", "aln": "-----MCSTPGMPAPGASLALRVSFVDVHPDVIPVQLWGLVG-ERRGEYLRLSREIQEAAATRG----QWALGSASASPGELCLVQVGL-------LWHRCRVVSRQAQ----ESRVFLLDEGRTITAGAGSLAPGRR--------------------------EFFNLPSEVLGCVLAGLVPAGCGAGSGEPPQHWPADAVDFLSNLQ--------------------------------------------------------GKEVHGCVLDVLLLHRLVLLEVPDVFQQMRELGLARRVPDS---LFRSLLERYLTAATASVGSGVPVLS----------------------------RVPLKQKQPGLDYFYPQLQLGVTEAVVITQVCHPHRIHCQLRSVSQEIHRLSESMAQVYRGSTGTGDEN--------------------STSATWEEREESPDKPGSPCASCGL-DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGIN----LNRVFGVQSCCLADRVLQS-----------------------------------------QATEEEEPETS-------QSQSPAEEVDEEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASK-------LDGVVLKPEPDDLCCVKWKENG-YYRAIVTKLDDKSVDVFLVDRGNSEN-----------------------VDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDE-----------------------------------SRTGEENISKVIAQAGYAKYQEFETKENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGSTELVVQEKVKRASVYFPLMQNCLEIK-------------------------PGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKN-TAAPH--QRNTLACLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLI----------------------------QPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALAS-INEELFNI----------------VDLLTPFQSACHFLVEKRLARPVKL-QKPLESSVQLHSYFYSTHDMKIGSEE---------------------------LVYITHIDDPWTFYCQLARNANILEQLSCSITQL--SKVLLNLKTSPLNPGTLCLAKYTDGNWYRGIVIEKE-PKK---VFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDIP-DHIPEEVVVWFQETILDKSLKALVVAKDPDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKK--ESEVLCSTTETLEEKNENMKLPCTEYLSKSVGYKLPNKEILEESYKPQINSSYKELK-----LLQSLTKTNLVTQYQDSVGNKNSQVFPLTTEKKEEISAETPLKTARVEATLSERKIGDSCDKDLPLKFCEFPQKTIMPGFKTTVYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYY-VGPPLQRGDMICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQG--FEVPDNKNSKKMMH-----------YFSQRTSEAAIRCEFVKFQD-RWEVILADEHGIIADDMISRYALSEKSQ---VELSTQVIKSASSKSVNKSDIDTSVFLNWYNPEKKMIRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDP------------------CIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLSGFNISEGLCSQEGNDYFYEIITEDVLEITILEIRR---------DVCDIPLAIVDLKSK--GKSINEKMEKYSKTGI-KSALPYENIDSEIKQTLGSYNLDVGLKKLSNKAVQNK-IYMEQQTDELAEITEKDVNIIGTKPSNFRDPKTDNICEGFENPCKDKIDTEELEGELECHLVDKAE-----FDDKYLITGFNTLLPHAN---ETKEILELNSLEVPLSPD--DESKEFLELESIELQNSLVVDEEKGELSPVPPNVPLSQECVTKGAMELFTLQLPLSCEAEKQPE-LELPTAQLPLDDKMDPLSLGVS--QKAQESMCTEDMRKSSCVESFDD---QRRMSLHLHGADCDPKTQNEMNICEEEFVEYKNRDAISALMPLFSEEESSDGSKHNNGLPDHISAQLQNTYTLKA-----------FTVGSKCVVWSSLRNTWSKCEILETAEEGTRVLNLSNGMEEIVNPENVWNGIPKLDKSPPEKRGLEVMEI----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5MCY1-1", "uniprot_id": "TDR15_HUMAN", "id": "B5MCY1-1", "name": "Tudor domain-containing protein 15", "aln": "-----MDSTSFLPT-FLDVDLTISHIKCLPKDILVKFQGIKSNECEFDYHVLQREIQHTPKVKN----NVEID-------EFCLVEERVS-----GEWQRGRVMEKKNE----LYTVLLIDRGEELRVAGPQIASACG--------------------------NLFELPPRVVFGIFANILPVG---------EKWSPKALNYFKSLV--------------------------------------------------------GIQVKGYVQAILPLQ-MFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKRPELSLG-------------------------NKDTSLDIQHVLDKLQPSLSVGSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVC--------------------------------QETSPTCDNFGLLCVARRR-NGQWHRGILQQLLPPN-QVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHIDWFNKDECLYYVTLQTQESTVNSKCLLKTVGTQVLCPMSDSKISNI-----------------------------------LSETSVSDVNSFAVESFMGNIEWSIDSLNKKGILKVGFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN-------DEMILRKPEPGLFCCARYSKDRRFYRAVITEINGYKINVYFLDYGNTDS-----------------------IPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQSV-----------------------------------EASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSESKNKVNIKKVISALLEGPKSKKYHSNNLVEN------------NLSLPKSLAVNISEFKNPFTLSVGPES-------------------------SWPYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSI-HSDPY--EIGQTACVAKYS--GKWCRAAVLTQVS-KEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQAFRCCLNHFI----------------------------EPVSCKLFSWTRKAFRDLWNFISSSRG---LLTCIIYALVIIHPNHLYNL----------------VDLQSSFTSAKEFLMNRGSAQYITL-SETFPSLFSLYSYCYSSFNIQIGSEE---------------------------EVYISHIYSPQKFYCQLGRNNKDLEMIETKITES--VNLQNFPKYDSNKMRVCISKYVEDGLSYRALAIPTD-SSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLSDLRDVDIPAEISSWFKDNFLGRSLKAIILSQESDGQLGIELYDGSQYINEKIKVLLHAYGKRHCDQACCMEKSNKINENKRFTTSLKGKTGNNYRHNVINKPSPVTYSERKIDQLMHPKNIHARFLKPSVCYKMEPVSKNKMKTSLNDGLKGIKIVPGAAHILENRRVGQKSVKVVSQSFIRALNQTTSQNPYDLIRPQIKDLPQPQIYLNAKVKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER-KSVKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEIWDDKTVD-----------YFTSKVHNKTVYCEFLKKHDQKWEVNMICDEKCVINELLKWKACSKLQK---SALQMPQVLSQKVRPGDNE-MKKGKSNESEGSMNSN---QQLFKIPLEEFKLGQLEKAEMLNVSKSGRFYVKLSKNKKILSDLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCG-IYEIVPVCNTKLLSNEIRNIPRQAVPCKWIWFENSK----NISFECLFADLEINILFLKYLDAVW---------EVEILVDDLLLLEYLNLNTVPVEEN-KLRLAEIVYNIESKTPVSSCTIKSFTWVQFQNDRQYSGIATAVSDPSDFSIQLEDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSS--CLFKYKSEDQWNRVEISEVSPQS-----LCLVLVDYGFSFYIRYSE---IIN--LKVVPEELLNLPRLSYPCILYGILPAKGKHWSEEAKIFFRDFLSKPDLVFQFREYHSETKLKVDVIHEKNNLADILVASGLATYSKDSPHLDAITATESAKN--PI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZPL0-1", "uniprot_id": "A0A8I5ZPL0_RAT", "id": "A0A8I5ZPL0-1", "name": "", "aln": "-----MDSTSLLPT-LLDADLTVLHIECLPKDILVKFQGKNNSECQFDYHILQREIQYIPKVAN----NLGID-------EFCLVEERT------GEWQRGRVLGKKNE----VYTVLLIDRGDELTVDSTRVASAYK--------------------------KIFELPPRVIFGIFANILPVG---------EKWSPKALNYFRSLV--------------------------------------------------------GIQLKGNMQTILPLQ-MILLEAPKVISGVLELQLGRFVDRDTFRLIVETLKEIPQPMPDLLRHKRPVLQSR-------------------------SKSTSLDMQYVLDNFQPSLPVGSLDSIKVSSALSPSKFYCQLLKQIPELEDLTERMNLHYDTGD--------------------------------QENSPACENFGLLCVAKGT-NGRWQRGILQQVLPDN-QVKIWFMDYGGSESVPSVHVKKLKQDFVFAPLFSFPCSLTYLHSPDQEVRKQQLTVFKQALLGHVVSACIDCFSEDERLYYVTLQPQESAAHAKCLQRTRSTQIHCPAFEPDIS----------------------------------------KALDDAGTYRTDSFVVDVQQPAGGLNKEDDLRAAFAIKTVKMEIESTYIAFVVNVLNPSNFWVRINKYQNKFQDLMRTINMFYNKPEN-------DELTLRHPGPGLFCCARYSKDRCFYRAIITEVDDYRINVYLLDYGSTHS-----------------------ISLFDAKILLPEFCELPPLAVHCSLAYIAPVTKVWIKAATDYFKKIVLNKAILLQVIRKRDDKYMVNIQNV-----------------------------------EAPENTDAVSLMLQAGHAKPAEVPSSGFHKSVRDRLVLKLNTLHEK--SVVTSVPVKRPEPERYHSNKLKGN------------ISSLCRFLDLKVS-----FNLVFEPNP-------------------------SQSYKEYVFKPGKLLEVNCSYCHGPGDFSCQLQCKLEDLKLLMEQIQAYYSI-HPEPY--QTGKVACVAKHSRDGKWYRAAILTQASEQEVELIFVDYGNQERVFIKDLCAINPHFLALEAQAFRCCLNYLV----------------------------EPITYKLLDWTAEASRDFGNFISSCGG---LLTCIVYALVLIHPRCLCNL----------------VDLQSPFTSANEFLLRRGSTHHSAF-SRPLPFSISLYSYYYSSFDVKIGSEE---------------------------DVYISHVYSPKRFYCQLCRNSKDLEMLETRITEM--INLKMCSKYDWNRMRLCISQYIEDGLSYRALVKPTA-SASDTCVYFVDYGNEQLVKENMLCAISDQFPELLFTPMQAIQCFLSDLRDIDIPGEINRWFEDNFLGKPLKAVILSRESDGQLGIDLYDGYQHINQTIKLLLNVYGEKHSKQAWCVGKNQRLN--RVSAVSLKENTESKRCHNAINKTSLATHPANKTDRWMRPQSIYSRSLKSSVCCKVEPMPKSKVKKSSKDRLKNIKFAAGSVHIPEDSDTGPNSEERVSKLLTKDLNQSAPQSPQVLIRPPITDIPQTHIDLSTQIKGSAPTIHHPANFHMASTENGNEATELTDVLKEKTDSQKNR-NCLTLLVRD--HAEYGNDHATSRGVTKNVLAEGSFEVEVFDHGNTAIVNGSKVYSINRELLTIPRLGIGSFLHRVRWDGPIEICKSKIAN-----------YFAS-VMKGTVFCEVWKTPDQKWEVNITCGDKCVIKKLLRWSPCPKPQK---LALQMPQAISHKVSPHEADNERTGRVNMCGGSMPFLPFSQQLGENPFELLRHEQLEESKTIYISETGKFHVTLPENQKT-SDLALLKAP-----------------------------------------------------------------SGEIISSPRRGVPYKCFWFTHST----LEFIVCLFAHLEMSILSLKYSDYTW---------EVDLLVNGLLPLGCLNVATSQVEEQRKQRSSGTVFGLEPQTLWSPCTILPSVWPLLQNGKRYSGIATAVCDLSDFCVQLEDFFDIMKHLFTLLSDVPEPLQALPSEHMIPGSS--CLFKSELEDRRSRAEISEVSDQS-----LHLVLSDLGRSVHVPYSE---ATN--LKSVPQKIMNLPRLSYPCGLYFVLPAMGKLWTNEVRQLFQDCRSKPGLVIQFRENGPGAVSEVDVIQENDSVADTLVASGLARHPKNSAHPDGITAPGCMKA--GHKRQSRTICSLLDKHCYKKEDVN-YSRNKQKLQRRKRMKRRNVARHLLKKSHASKKLYSGNLKLRRQVLSGKLNFQSAVLLGICVASLSGGVPDPLENST-----------DCFGNICEDLSTEGLQEKSYTIDSKAAGANEKITVERLKMETDPGALPIQTSNLATELCAFFCYLVLRHHLIKSSSRSNELAIFLSQLPECLVANNFGNLSCF-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1R237-1", "uniprot_id": "TDRD6_DANRE", "id": "F1R237-1", "name": "Tudor domain-containing 6", "aln": "-----MCSIPGLPSKGSNVPVLITRVNLNPSCVLVEFWGNFDEDRKFAYQQLKKEIQYPRECFSESDGN---------PGDLCLVQVYE-------TWYRARIVSRDSD----EYSVFLIDEGRTLRAAVNTLAWGKS--------------------------DFFYLPPEVEFCILANALPLS-------PENNWSSMALEFMKTFC--------------------------------------------------------GRRVNATVQDVLVAHRTFLLDIPCLSRQMFEMGFAKKLYSD--QFMEFVVRSLQASTGTSDLKRISSIRTK-------------------------PVEIIEQKEKQQAYMFPELQTDTVETVVITEVTSPFRIFCQLKVFSQELKKLTEQITQYYEGRVG--------------------------------SYFARAENLGSPCASRGS-DGKWYRSVLQQVMSANNVVEVLHVDYGKKQFVQVENVKPLASEFFRMPVVTYVCSLHGIVDKGVGWTASQIDYLKSLLLNRTVIAKFQYQSLSEGVHYVTLYGEENTN----INKLFELKPKCSLDSDMTLAD--------------------------------------FAVQKSPSSQKSKISRTTESTHINETYSDLKVNKPVFFTETLTPNSTHMAVVQHVDSPGKFWIQTQRYADEFDLLMNGLGNLYSDPTS-------TESLIRKPVVG-LICAAKAQDGVFYRAAVYKVIDKTAEVYFLDYGNTEV-----------------------VDSFNLRQLPLRFQQLPAVAVKCSLHGVKPRLKLWEERATLFFSKLVRDRIIDLHVQDKQQDTHIVQLVDP-----------------------------------SLDGEKDVSKLLCNAGFAVSEKSIVDYSATRSCGLKTTHASG-----------VFLTGTQPQTPCSS--------------------------------------SVVMDS-------------------------ASAFKEYLFPIGSSLEVTVSYIENPNDFWCQKARNAACLEVLMQDIQRFYSHSEFEP----LLEAACVARHPETGIWYRALVIQKHQTPHVDVLFIDYGQTKKVAIEDLRKITPAFLKMKGQAFRCSLYNLI----------------------------HPVLHSSSDWSTEATLEFQEFVDAAASMNVPLKCTIFAVMYDSQKVVFNV----------------VDLETPFQSICNLLVQRRLADRAPS-KRSPLPPFRLDTYYYSTHGVKTGCDE---------------------------KVSITCVKGVNQFFCHLARNSDEVEKLAEKVNFL--CHQLEATKCP-QTFGTVCFAKYTDGLWYRGQIKSTK-PSV--VINFVDYGDTLEVDKSDLLPVPIEAGDIMSVPVQAIECGLSDMP-EELPCEVDNWFRKFADSHCFTALIVAKEPAGKLILELYDGKTQVNALIKQKFHNEIHKN------DASTFKIYGLKSRAAESVEASACKKESSTGPKRDAIDQVPKSRESHAIQRSNDVASKQ----------PQSRWGFSTNGRPEPTRDSGTINNCQKQPELRTSQGNLRHPCTSSKPEVVKPKP---QALLKESALPIKSIKPGLEAEVFISHCNSPCSFFVQFATDEDDIYSLVEKLNADQSRCRNI-DSSDIHEGDLVCAMFPDDSSWYRAVVRKN-TNEKIDVEFVDFGNTAVISSKNVCHLGQSFASFPRYSIHCSVHKLNVDSKDQELAPNFKQ-----------VLEQ--NIEKVICTFVKMSGTMWEVRLDVNG------VVLGSVCKDHVK---PEIAIPDLKDAASEIKVCTYYKNPDIS-----IGQVITGYTSYIKGPQLFWCQYVAMDKLQEISDMLQNIGNAS-ETTLREDCMPVGSA------------------CIALFTEDNLWYRAKVTSKDLDTLSITFVDYGN--ESKVKIGDVKALPPKLSDVPPHAFDCQLEGFDVSEGFWDETADDAFYELVHDKPLNITIEKMGNSEMPHIVKLDCDGVDINTTMKSHWKTRNPETPPAELFNGAEMASDDDYVASKVNIDSVVTFDTDTDPADNETCTSALEMELSEQENLLSSTGVENEAQIDPLKMATENVTLPITESTVLSETHKKLETITEDEPVLGFTGLSDTNQH-----AVSKETDVGLPQHSEGASSVTIDSFLMNNTDSQLCIVEEPEAPSYEIIQSNLGCLRRATEKKPVGSECVIWSQVRRSWCTARVLKVSEEATLVLLEKYDSEVVVDPINIFEIMPEKPLQIACIEAAIANDDATKETDATLENSASKLYQTEVSDANGIAVALESEDLNGKEETFIDQMAPNDELAGQPQEEESVSCSAFLEDSKAKHMLVEGAQVHDLVQGLCPDDVESKDPQDDLNTSFEEQNDGAKMSTAVDLLLDFLDTAPRDKVQDVSETDALLEEFNIHVTEDLIVLTSDDGAESDTASDGTLHGDAVAMEVGPDTEESSCFQERSNASDCTSAEDSQVTHLTLKVEDASDDVIFVGVLQESQAVVHEPESEKEKRD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NXB8-1", "uniprot_id": "A0A8M1NXB8_DANRE", "id": "A0A8M1NXB8-1", "name": "", "aln": "MERTKEESKLPAPCVLWPVELKLTHIDCRPENKLVHFQGQYMTICELDYNILQVEIQNAVKSKVS-----------VQVGDVCLVEDSGS-----GRWYRGRVQNIEKD----KFHIFLLDHGDMMIVGPNCLSSISD--------------------------TLLMLPPKIVCGFFANILPIQ---------SQWDSLTNSYFSSLK--------------------------------------------------------GSRIKGYIHARLPYH-ILILEVPEINSDMIKKRLGRHVDTSTFLLLVEMLIDEPIPQSNESVPDLLIEKQIG-------------------QEYCLKSSSLLGFEEILSLNGPKLKVGQEVEVVVAAAVNPGLFYCRLSSMGKDLQEMSDKLALACESGSG-------------------------------CLTNDLDENLGLLCAVKGK-DEKWHRG-FVECLPLNSQVKVVFVDSGYCESVKVENILQLPSEFLSRPIMAFPCSLSCLEKQDEDIKNQQVDALKTGLLGKVLEIEIDDFRKDQNLYLVTMNIAQKHS-----EKQAGVKP-----------------------------------------------------HESDNLRSNSNFPYDVLSNVSAGETKVAQTSDSNPNRAIPDDSFFEGYVVHVQSPKHFWIRTKEHNPNFENMTKEMADYFSKLQL-------HEEVFEDLVPGALCCAMYENDMQYYRALVVDTLDKGAEVFFIDFGNTEK-----------------------VPGILIKKLPKKFAIHPEFAMECALAHVAPHEDIWTTTASNYFREVTSDKTLMIHVVHRKNRKYVVDLFER-----------------------------------DAEN-CSIATIMTTAKMALDWRYNPALASVEIERPCKYKGNALSKKKNKKDLRVVTFHKVTSSMSSPNQIEHEWEP----------------QNYLEKHTPSETLKPEVVP-------------------------AKTLKPMHFKPGSEVSVICSHVNTPSDFWCQNVSTKLDLDKLMEEMQLFYQT-YTSGL--LMPALCCAVKSPHDNQWHRACMIGQHN-EQLLMILVDVGLIIQEKLQNIQTLQPQFLELPTQAFRCRLN-FI----------------------------EPIGGS--SWSSEACNLLRDFLFKCTS----SKCRIYSQVYEKGKGLLNI----------------VSIHTPLQQASTYLVEKGVAAEVQAPDKHTISSAHPWSFVYSSFNISCGSEE---------------------------LVHVTYVCSPWEIYFQLDRNTEILNRLTERVAEE--SQLFTSISDN-CSSKVCLAKYFCDGSWYRALVHPVQ-SNQHVSVVFVDYGNKEIAEKTNVMAIPTTAVDVLLTPMQALRCSLLNLPEGEHLPEVNKWLETEILNKSFKAKFVSSDTNGHFVCDLYDGNLHINEKVKELMAAHGVAQS-----------------------DLAVNKLELDFPKEEAHASLPNCKRNHKATRRSKAKQNGK---------------------------------QTPRSTNHSKKQLKEPVEMEDQNAPCPLKVVPSHQSLPKLCDLPAVTMKPGSRGVGFVSHSISAGRFFIQMEDDEPKLLQMIEELNGTNFKDKRRNVETEIKVGDLVAAEYEEDLALYRAVVTNVLNSDLLAVEFIDYGNTATVDRKNVHMLTNTFLSQPRLSMPCTLAKP--------HPFENDD-----------SFTEKAVGKPLLVEFIQSLEGSWKVNIEFDDDHLQGDLKYDADHSKDVD---LASQDKLPKDSQTQSQSDQYNQSIKEVQSFQQKEQFRHQLANNQTVRTFQQKTTSNTQSICEFRTKPTEVRTIQQKTKSNTQQRKCELT------------------------------------------------------FATKQIKKAAIYVQTSVKTRDIWRRKYKKQNFKPKVVVNAEPQCETSIPVAKISEGLQENVQQE--------NKNSESLACVALHDVKDSEPVKIYEDLSVVTDHPPSPKTSLRTNLDPPQTLFQAPVKMNFEYEGFAAAVTTPSEFYIILEDLLLIADTVSSILENLPEVLEPLPEVHFVPGTS--CLVKLVENQKWCRAEIVQCDSTS-----VLINLVDCGLYSVLSRLD-----ASQLRKLPEELGRLPKVTYHCLLRGVKP-NAPDWSDDAILFFQNSMCHKNLKIRFRQHVSETQWEVDIITGSQNLAKELVDSDHAMYIDKMLGIRFQQDQGLNQE--PNQQAISSTVNDLSIITEHTSEAKKQVTLSAKKPSEESVGEKDTSDHLNSGGDDLGQVDRETLGLPSGIKQCMLM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TGE0-1", "uniprot_id": "A0AB32TGE0_DANRE", "id": "A0AB32TGE0-1", "name": "", "aln": "-----MCSIPGLPQVGSRLTVHITRVNLTPHTVLVEFGGNLNRGQENREIWQQLKDIEVPRRRQ--------HAFEGKPGEICLVYEDR-------TWHRARIISETEY----EYNVFLIDDGKSLWTTSEVLTKCPH--------------------------NLCGLAPKVELCILTNVSPLC-------LESGWSAGASKFIRSLC--------------------------------------------------------GKNISGCVQDVIMPSRIILLDVPSISKQMYEFGFAKNTPCKNFKILVTYSLHLPRSPSIQTDLLTTNGQ----------------------------QEHASNSDRLWQYLYPELSPGTIEIVTVTQVVHPLKIYCKLCVFSQELKKLSVQLYEHYEDAFS--------------------------------AQIPVPLCDGSPCATKGS-DGKWYRSVLQQN-DISDVVKVFHVDYGIGDFVKLSNIRPLSARFFHLPVVTYGCSLHGVIDKGVGWRTDQIDYLKSVILDQILVGKFEHYSVSEGVYYITLYGNDNVN----VNLTFGHKEHCLAVNEKMCGDPTLDTLNKVTYGNMHGRNDSLQSLHSAHLTECSSSVEDVNVVGPSKAEGNLQSTKGGYTLNAATTSPLQTDAYVDVPPKIKVGAKMKLHITCVQSVNQFYGHFAQNTDAVTKMTKDIQQLCRKRPQ-------AKFSISP----KMMCLAKFSDGQWHRGQIESVHP-KILVQFVDYGDLVV-----------------------VDKSDILPFPPNANAIASLPIQAVQFELFNVALPEPCELNEWFKNYATDCMFNVVVKLNSSGKLSVEMYDD-----------------------------------KTNLNLKIKDLWSKTKRNESINTKGIVKTRGFKETSEGMEFREVRNSFSTTSQAHERTLKPVGQARTEQNFQSATG-----------YSNATGNNRAWPNVLQQQVMAYPK-------------------------LTELPLRTIDVGYVSDVYVSHCNSPSNFFVQLTTDEDEIFSLIEKLNCTLISDLQVELNLLQSDDLVKAEYPADGAYYRAVVKSKKN-GMVQVQFIDFGNEVTLLPTKIKQLDKQFLSTPRLSIQCMLE-------------------------------DGKRRGKRDWTQEEIMTFKEAAGENGE-----KKIQCKFIQEDANCWLVS----------------LEHQEGWFTVKSDAQSESQVHCIKN----------TQPLTFKKPAVTPGQTV---------------------------EAYASSIVGPNYFWCQFK-NSEILDKISLLAQEIGNSSHTKAIQPDQLRQGGICLARFSDQLWYRAQVINTH-EKVS--VLFIDYGNESEIDFNSIKALPTKLLESPPQAFLCQLQVLGSVEGTWSDSAADKFFEILVDEPLKVTVQNMVVTPNPTMCPQFSVLVECKELIVNDLMKDFLSDP-------------------------------KPQVSSKGSMAKTNAGKDDFGVTNSEAVQKNK----------------------------------TPNLNSSTTPSIDDVNNSAALTTGVNMMDPESMQSFPRSVDLPQRVIQPGTMSEVYISHINNLRSFYVQLKEDENTLFSLTESLNSHQPSEKDEMHGLSVQQGSLVKAMFPEDDSWYRAVVKCAPENDMVFVEFIDFGNEAMVSSLKICRLDEHLLSYPRFSIHCSYSLNDQFKGMKKQEILFKE-----------VLGG-AGENTLSCSFIKKDDIAWEVTMTPCEG------TSDSFSKKWDQ---LDLNALSVVTKPVKETFNFLFKKPDVS-----LGQTIEAFASCIVGPDYFWCQFSNSEILDHITQVAQECGNSSETQPILLDNLDSGSP------------------CLARFCDDQMWYRAQVIKKCTNTVSVLFVDFGN--ESEASEGSVKALPCDLLESPPQAFLCRLEGFNPSGGSWDSEATDNFYELLVDKPLKVSVQCIDDS------------------------VEPNSPPYYVKVESSQSLVNELMAKFWSNCTHHDQNSAEVIESCEKDVGSAPVDQSISEDKTSECLAISTEDNHTSVPTCPELHRDNP---------------LMENGNLHNVPENEVDDKI-----VGADVIATTTNSDVAAND----------PANSDLEIQEGYHEPDGDSVVSAEQAQLHTEENKEDGEESTSQNADLPLTPNRSSDWVARLEKQMLPMVCTEDSCDSKCIFK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25823-1", "uniprot_id": "TUD_DROME", "id": "P25823-1", "name": "Protein tudor", "aln": "--------MNGQARIALPSKVDLYITHVDHVGPYLKVYGHVNRDAASLISERIRNLLPTCFAIEP-SWSVERQQALLIPGTFCIFKNINGPAPGDVEYRRIRVVSADLEGQSMRAEIDFVDFGYKRTVDSHDLMFPKQPKLLQNIPLHCFQYIVLGICSEWDQTDLAEVRRLVVNQIVKITVEPTQICDQKFASLRWKDFELNEFLVQQKQIGVSVDKQLMMDHCKKLWKDNPQSPVTEYNNNSIHNSKTPMEIAREQLAVRQSLAARLDAQRSVQVTPSRPLNADAPDYTPKHLPLVNVTNVQVQMPGLNNTQKPVFVSTNPYNRANYQPAVPAAQPYVPKANPRSQYTYYNVRMNKPINAMPPPAGPHVPIQHFNQQANNVSLSYVPARFTPPPTPSIAQHQIPIPAFRTTSLTVGLTYDVVISYVENGPYLFWVHLKSSDHDLSTMMGQIERTKLKALAQAPELGTACVARFSEDGHLYRAMVCAVYAQR--YRVVYVDYGNSELLSASDLFQIPPELLEIKPFAFRFALAGTKEIEP-IDDSMKRIFKKSAIYRNFELTVQAPESVGSMQTCHLNQNGTNMLELLRQLKNSRQSYKKAEQLENDD------------------------------------------AVEIRFIDSPSNFYVQKVANIGKFEQLMDEMFSYYNANQRVPDQLILGAPCIVKCDQEWYRAEILRVDDSVIVRHVDFGYEQNVKRHLIGHIAEKHLEMPRQAIKCCLKGFENSELSEDKITDQFEMLAEESNIRRRTFSVRIFRIEPDGLNVVNLLAKNLNVMKKLYKLSMPFEQYLSLEKGQFNANNTRAESVISSELNKSHILNSTSIGETENRLQEQEKEQQQKKVDVRQQQLAVEIPQAVKSVSGSKNSTDWDKRSSTSAGSKDSKRQQQQQIQRIDRHLDFSCETQSTGSYSSGMSSPRKGNRQQNGRTPIQSPRHNEKQEAKKNARFSNSESPRRSRDGQQGNQRSQNAPQGYAQKPQRQKSTLDGNISSKRSSGVGSDIASSSSESVAAAKPEKYVSLDKPYALQEMKTPSKEAASLSWWLSPFQFYIVPKSVSAKYDNIMRDMREFYRQKQHQPLQLKVGSTVVVRQRKDNAILRATVTACNHMMRKYRVFCVDTGSLITVTSEDIWQLEQRFADPPCMAHRCSFHSVVTNYDPLYIVDRMETFVPVNAKVDCEFVSKEKSNQGSNTSSTCSYTVNIFVNGASLRDMLVKAEFLTEVAPEIRVNLLAGQQIRGKFTSIRDMTSFKVQFDYGNNVNFLCTYDDAKFVKSNPNLARRFKEFYEGKSFALNVKNVCENNIVHLRPVMPLFMEDRRSFICPYPVVLSSFQALVVYTAKPYRVYVQPQAIVPSMQTLLDNMYEHYKAKGDSLKKFDVGQICAVRSSDGNWYRARISGKDSNAACFEVFYIDYGNTEEIKRDDIKALDAKFYEHASGFAVEINLPIGRPS---NDTKLKARISEILEEKVVTIKSIEVRRSHLIADVILENNQSVIDLLKAEKLVPGKDLDYMRKQMEKGKSRTYEYIETVDLTLDEEEDKGRKETVSKSGSANASPKKKQHNDKDREPKKSKP-------------------AEPARTVAPQPVALKTPSPVPAEPAPVPKPATPVPEVVEVPEINPTVREAAAESKQAPAQEDPYKDLDCVVLSHCDNPAQFYVHPIDQLSKLNQLHENLQIVSPSLPQL---MNVVNGADCVSMYSVDKCWYR---AKIIDAELMVLLFIDYGNTDCVS-DATDIKESMWSHIEPFCLPCALPIRPKGTADWVDAANGIFNESYSKVPRLEYLTQGDHYTTSYVNMYIDGEDVAKKLIADGFARPLEYLASGCSCYISHVNGICDFFIQLERDSKALELIELYLRKKDTLKPLEGFEKGLIVAALFEDDELWYRAQLQKELPDSRYEVLFIDYGNTSTTSKCLMLSEEIASLP------------SLSKKCSLQLPDAYISWSPEAEAKFAELTGEGELVFTTQLLKPGQDHVTIDLLLDGENIIDRLLPLCQRKEPKEASKESLAVTTKAIITHVENTSRIYLQFSEK---------DSLMDIICEKLNGSKLQPKTEKAAVDDMCVVQFADDLEFYRSRILEVLEDDQYKVILIDYGNTTVVDKLYELPQEFTLIKPVAEICSMEPSAIFEKNKALTLTTFDALLDSCKGVVAVEFVNKSASPPVVRLTTKDKRSLKIYEHLQKLVQAELKLIQKRNENSECIISYGNSPKSFYVQMKHNSADLDLIVKTLQSLKKEKLKKLIDPTTNSNGVCYSQEDACYYRCSIKSVLDPSQGFEVFLLDYGNTLVVPEVWQLPQEIEPIPSLALHCQLSKIPMDVSDEKLEEAFAALLEQHFGELYEITTQPNEDETKPLIAELRINYKDFVQELVSTVTGVQKPLEAELHNCVVVQFDGPMSFYVQMESDVPALEQMTDKLLDAEQDLPAFSDLKEGALCVAQFPEDEVFYRAQIRKVLDDGKCEVHFIDFGNNAVTQQFRQLPEELAKPARYSRHCELDASTISKCDAALLQSFIDTRFSETFQVEILATKGTGTHVVRLFYQSKNISEKLQECQ-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :.. * : .*:. : * *: : ::* * . : : : : .. * . : . .: . : . : * . : . . : . * .: :. : : * *. : : *. . .: .:* * : : : : . .:: :* . :* : : . .: : : : . : . . : : : . : . . * .: . : : . . . . : . . ::: . . . : . : . * * * :: .:. . : : :* * .: : * : :* : . . . . .. . : : : : : * **. : ::*:*: : .: : : : : . * . *.: : : : *: : : * * . : ..*.** : : . : . : : . . . . . . . : . . . .. . ", "identical_positions": 37, "similar_positions": 181, "identity": "1.41%" }, { "cls_id": "homologset.agr.FB:FBgn0003892", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RA51-1", "uniprot_id": "M0RA51_RAT", "id": "M0RA51-1", "name": "", "aln": "MVRPLS---------------------LGELPPSYT--PP-----------------ARSSAPQILAG---SLQAPLWLRAYFQGLLFSLGCRIQKHCGKVLFLGLVALGALALGLRVAVIETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGANILTPEALGFHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENG-MIERMIEKLFPCVILTPLDCFWEGAKLQG--GSAYLPGR-PDIQWTNLDPQQLLEELGPFAS-------LEGFRELLDKAQVGQAYVGRPCLDPDDPHCPPSAPNRHSRQAPNVAQELSGGCHGFSHKFMHWQEELLLGGTARDLQGQLLRAEAFQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASMVLQAWQRRFVQLAQEALPANA----SQQIHAFSSTTLDDILQAFSEVSATRVVGGYLLMLAYACITMLRW-DCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPPN--TPLPERMGECLRRTGTSVALTSINNMVAFFMAVLVPIPALRAFSLQAAIVVGCNFAAVMLVFPAVLSLDLRRRHRQRLDVLCCFSSPCSAQVIQMLPQELGDR----------------AVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLLS-----------PTSDPLGSELYSPGGSTRDLLGQEEGTRPKASCRSLLCAHWTLAHFARYQFAPLLLQTQAKALVLLFFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPAAQAPRTWLHYYRSWLQGIQTAFDQDWASGRITRNSYR-NGSEDGALAYKLLIQTGNAQEPLDFNQLTTRKLVDKEGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPAAQPLEFAQFPFLLHGLQKTADFVEAIEGARAACTEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLLCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTSHGSRNLRAARALEQTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQIYKESPQALSSTAPQRGGLRWGVSP---------------------------------------------------------------------------------------------------------------------------------------------------------TLPQSFARVTTSMTVALHPPPLPGAYVHPASDEPT-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35595-1", "uniprot_id": "PTC2_MOUSE", "id": "O35595-1", "name": "Protein patched homolog 2", "aln": "MVRPLS---------------------LGELPPSYT--PP-----------------ARSSAPHILAG---SLQAPLWLRAYFQGLLFSLGCRIQKHCGKVLFLGLVAFGALALGLRVAVIETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTAHQEGGNVLTPEALDLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENG-MIERMIEKLFPCVILTPLDCFWEGAKLQG--GSAYLPGR-PDIQWTNLDPQQLLEELGPFAS-------LEGFRELLDKAQVGQAYVGRPCLDPDDPHCPPSAPNRHSRQAPNVAQELSGGCHGFSHKFMHWQEELLLGGTARDLQGQLLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASMVLQAWQRRFVQLAQEALPANA----SQQIHAFSSTTLDDILRAFSEVSTTRVVGGYLLMLAYACVTMLRW-DCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPPD--TPLPERMGECLRSTGTSVALTSVNNMVAFFMAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAILSLDLRRRHRQRLDVLCCFSSPCSAQVIQMLPQELGDR----------------AVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLLS-----------PASDPLGSELYSPGGSTRDLLSQEEGTGPQAACRPLLCAHWTLAHFARYQFAPLLLQTRAKALVLLFFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRSWLQGIQAAFDQDWASGRITCHSYR-NGSEDGALAYKLLIQTGNAQEPLDFSQLTTRKLVDKEGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPAAQPLEFAQFPFLLHGLQKTADFVEAIEGARAACTEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLSPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASIGIGVEFTVHVALGFLTSHGSRNLRAASALEQTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQVYKESPQTLNSAAPQRGGLRWDRPP---------------------------------------------------------------------------------------------------------------------------------------------------------TLPQSFARVTTSMTVALHPPPLPGAYVHPASEEPT-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6C5-1", "uniprot_id": "PTC2_HUMAN", "id": "Q9Y6C5-1", "name": "Protein patched homolog 2", "aln": "MTRSPP---------------------LRELPPSYT--PP-----------------ARTAAPQILAG---SLKAPLWLRAYFQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENG-MIERMIEKLFPCVILTPLDCFWEGAKLQG--GSAYLPGR-PDIQWTNLDPEQLLEELGPFAS-------LEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAHELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENA----SQQIHAFSSTTLDDILHAFSEVSAARVVGGYLLMLAYACVTMLRW-DCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTEALPG--TPLQERMGECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSAQVIQILPQELGDG----------------TVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLVP-----------PPSDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARYQFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQAAFDQDWASGRITRHSYR-NGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPPAQPLEFAQFPFLLRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPEILSPPAPQGGGLRWGASS---------------------------------------------------------------------------------------------------------------------------------------------------------SLPQSFARVTTSMTVAIHPPPLPGAYIHPAPDEPPWSPAATSSGNLSSRGPGPATG----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98864-1", "uniprot_id": "PTC1_DANRE", "id": "Q98864-1", "name": "Protein patched homolog 1", "aln": "MASDPRDP-------------GPAGGVFGDLPPSYTRSPPP---VNSDLLRRPSYCHAAFALKQISKGKAVGQKAPLWIRARFQAFLFSLGCHIQRHCGKVLFIGLLVFGALSVGLRVAAIETDIEKLWVEAGSRVSKELRYTKEKQGEESVFTSQMLIQTPKQEGTNILTQEALLLHLEAALSASKVQVSLYGKSWDLNKICFKSGVPIIENV-MIERMIDKLFPCMIVTPLDCFWEGSKLQG--GSAYLPGM-PDIQWMNLDPLKLMEELSQFTS-------LEGFREMLDKAQVGHAYMNRPCLDPSDTDCPHSAPNKDPWQVPNIAAELQGGCHGFSKKFMHWQEELILGERVKDSQNALQSAEALQTMFLLMSPKQLYEHFKDDYEIHDINWNEDKATAILESWQRKFVEVVHGSIPQNS----SSNVYAFSTTTLNDIMKSFSDVSVIRVAGGYLLMLAYACVTMLRW-DCAKSQGAVGLAGVLLVALSVAAGLGLCSLLGLSFNAATTQVLPSLALGIGVDDMFLLGHSFTETRSN--IPFKERTGDCLRRTGTSVALTSVNNMIAFFMAALVPIPALRAFSLQAAVVVVFNFAMALLIFPAILSLDLHRREDKRLDILCCFYSPCSSRVIQIQPQELSDANDNHQRAPAT-PTYTGSTITTSTHITTTVQAFTQCDAAGQHIVTILPPTSQISTTPPSMVLSTPTPTTDPYGSQVFTTSSSTRDLLAQVEEPKEGRECVPLPFFRWNLSSFAREKYAPLLLKPETKTVVVVVFVALLSLSLYGTTMVHDGLYLTDIVPRDTQEYEFITAQFKYFSFYNMYLVTMDGFDYARSQRQLLQLHNAFNSVKYVVKDGNHKLPRMWLHYFQDWLKGLQATFDADWEAGKITYDSYR-NGTEDGALAYKPLIQTGSKKEPFNYSQLTSRRLVDGDGLIPPEVFYIYLTVWVSNDPLGYAASQANFYPHPREWIHDKYDTTGEN-LRIPAAEPLEFAQFPFYLNGLRQASDFIEAIESVRTICEEFMRQGIKNYPNGYPFLFWEQYIGLRHWFLLSISVVLACTFLVCAILLLNPWTAGVIVFILPMMTVELFGIMGLIGIKLSAIPVVILIASVGIGVEFTVHIALGFLTAIGDRNTRSAVAMEHMFAPVIDGAISTLLGVLMLAGSEFDFIMRYFFAVLAILTLLGILNGLVLLPVLLSLMGPPAEVVPANNAN--HLQSPSPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------PMPPPMN--HHGYYAGHIPKASHQAFSETSDSEY--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q13635-1", "uniprot_id": "PTC1_HUMAN", "id": "Q13635-1", "name": "Protein patched homolog 1", "aln": "MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETG-YMDQIIEYLYPCLIITPLDCFWEGAKLQS--GTAYLLGK-PPLRWTNFDPLEFLEELKKINYQ------VDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNS----TQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRW-DCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQP-------VTVTQDTLSCQSPESTSSTRDLLSQFSDS--SLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQK-ADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYK-NGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPG---YPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61115-1", "uniprot_id": "PTC1_MOUSE", "id": "Q61115-1", "name": "Protein patched homolog 1", "aln": "MASAGNAA-------------GALGRQAGGGRRRRTGGPHR-AAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETG-YMDQIIEYLYPCLIITPLDCFWEGAKLQS--GTAYLLGK-PPLRWTNFDPLEFLEELKKINYQ------VDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSAHALQTMFQLMTPKQMYEHFRGYDYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNS----TQKVLPFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRW-DCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYTSHSFAHETHITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQP-------VTVTQDNLSCQSPESTSSTRDLLSQFSDS--SLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQK-ADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQGLQDAFDSDWETGRIMPNNYK-NGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHTNNGSDSSDSEYSSQTTVSGISEELRQYEAQQGAGGPAHQVIVEATENPVFARSTVVHPDSRHQPPLTPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPSNRDRSGPRGARSHNPRNPTSTAMGSSVPSYCQPITTVTASASVTVAVHPP--PGPGRNPRGGPCPGYESYPETDHGVFEDPHVPFHVRCERRDSKVEVIELQDVECEERPWGSSSN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18502-1", "uniprot_id": "PTC_DROME", "id": "P18502-1", "name": "Protein patched", "aln": "MDRDSLPR---------------VPDTHGDVVDEKLFSDLY---------IRTSWVDAQVALDQIDKGKARGSRTAIYLRSVFQSHLETLGSSVQKHAGKVLFVAILVLSTFCVGLKSAQIHSKVHQLWIQEGGRLEAELAYTQKTIGEDESATHQLLIQTTHDPNASVLHPQALLAHLEVLVKATAVKVHLYDTEWGLRDMCNMPSTPSFEGIYYIEQILRHLIPCSIITPLDCFWEGSQLLGPESAVVIPGLNQRLLWTTLNPASVMQYMKQKMSEEKISFDFETVEQYMKRAAIGSGYMEKPCLNPLNPNCPDTAPNKNSTQPPDVGAILSGGCYGYAAKHMHWPEELIVGGAKRNRSGHLRKAQALQSVVQLMTEKEMYDQWQDNYKVHHLGWTQEKAAEVLNAWQRNFSREVEQLLRKQSRIATNYDIYVFSSAALDDILAKFSHPSALSIVIGVAVTVLYAFCTLLRWRDPVRGQSSVGVAGVLLMCFSTAAGLGLSALLGIVFNAASTQVVPFLALGLGVDHIFMLTAAYAESNRR------EQTKLILKKVGPSILFSACSTAGSFFAAAFIPVPALKVFCLQAAIVMCSNLAAALLVFPAMISLDLRRRTAGRADIFCCCFP-----VWKEQPK----------------------VAPPVLPLNNNNGRGARHPKSCNNNRVPLP-------------------AQNPLLEQRADIPGSSHSLAS------------------FSLATFAFQHYTPFLMRSWVKFLTVMGFLAALISSLYASTRLQDGLDIIDLVPKDSNEHKFLDAQTRLFGFYSMYAVTQGNFEYPTQQQLLRDYHDSFVRVPHVIKNDNGGLPDFWLLLFSEWLGNLQKIFDEEYRDGRLTKECWFPNASSDAILAYKLIVQTGHVDNPVDKELVLTNRLVNSDGIINQRAFYNYLSAWATNDVFAYGASQGKLYPEPRQYFHQ----PNEYDLKIPKSLPLVYAQMPFYLHGLTDTSQIKTLIGHIRDLSVKYEGFGLPNYPSGIPFIFWEQYMTLRSSLAMILACVLLAALVLVSLLLLSVWAAVLVILSVLASLAQIFGAMTLLGIKLSAIPAVILILSVGMMLCFNVLISLGFMTSVGNRQRRVQLSMQMSLGPLVHGMLTSGVAVFMLSTSPFEFVIRHFCWLLLVVLCVGACNSLLVFPILLSMVGPEAELVPLEHPDRISTPSPLPVRSSKRSGKSYVVQGSRSSRGSCQKSHHHHHKDLNDPSLTTITEEPQSWKSSNSSIQMPNDWTYQ------------------------------------------------------------------------------------------------PREQRPASYAAPPPAYHKAAAQQHHQHQGPPTTPPPPFPTAYPPELQSIVVQPEVTVETTHSDSNTTKVTATANIKVELAMPGRAVRSYNFTS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : :* * . ::.:::*: ** * .**. :*::.**.*.:.:: :.::.:**: * :.:.:.:**:: *.*:. ** **::. **: . *::***.:: . .:* :** **: : *: *:* :*. .* *..:* .. * ::::: * ** *:*********::* . .:. : * : * .::* ..:: : .: .: :.:* :* .*: :***.* : .** :***:.. : ::. *.*** * : *.*** ***::* :: . * *.*:*: . **: :::*::::. .:.*.:::*: :*::*** : . .. : :: . .: *::::*:**: **. *. :. * : : ** *:*** * :.*.:**:*****:.::.*:****.:*:*: ****:***:* ****:***.:*:* ::::: :: *: .*.*: ::: .. :*: *.::*:***:.*.****:*: .:. .:*:***::*:** ** * *::** . * : *: . : . :. : . . : : .*::.* . :.*: ** :::*:*::. .* :.:. * . * ***.:* ::*** : *:**: :.*: *: ** : *.:*.: ** :*. *: * : * * : *: * ** : .** .:* ** :: *:: . : *.:.*. **** ::*** .:*.: . : ..:**: :*:* ** *:.*.:.* .. .***.:: * ::.*: * *:** : *: :**:** *.** .:::: * * . : *: **.* **:*****: ** : : :. :* .:::: :::**. *:* :::: : .::** * ::******:*.***: *:*: : *.* ::*.*:*: *.:: * ::: :.*: .* ::: :.::**: * *:*::*:* * :: :* :.*:::*:***:.** .:: . .. * * . . . . ", "identical_positions": 317, "similar_positions": 421, "identity": "21.42%" }, { "cls_id": "homologset.agr.FB:FBgn0003896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61371-1", "uniprot_id": "ISL1_HUMAN", "id": "P61371-1", "name": "Insulin gene enhancer protein ISL-1", "aln": "-------------------------------------MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALRED-GLFCRADH-DVVERA----SLGAGDPLSPLHPARP-------LQMAAEPISARQPALRPHVHKQPE----------KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMK-QLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDID--------QPAFQQLVNFSEGGPGS-------------------------------------------------------NSTGSEVASMSS----QLPDTPNSMVASPIEA---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61372-1", "uniprot_id": "ISL1_MOUSE", "id": "P61372-1", "name": "Insulin gene enhancer protein ISL-1", "aln": "-------------------------------------MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALRED-GLFCRADH-DVVERA----SLGAGDPLSPLHPARP-------LQMAAEPISARQPALRPHVHKQPE----------KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMK-QLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDID--------QPAFQQLVNFSEGGPGS-------------------------------------------------------NSTGSEVASMSS----QLPDTPNSMVASPIEA---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61374-1", "uniprot_id": "ISL1_RAT", "id": "P61374-1", "name": "Insulin gene enhancer protein ISL-1", "aln": "-------------------------------------MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALRED-GLFCRADH-DVVERA----SLGAGDPLSPLHPARP-------LQMAAEPISARQPALRPHVHKQPE----------KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMK-QLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDID--------QPAFQQLVNFSEGGPGS-------------------------------------------------------NSTGSEVASMSS----QLPDTPNSMVASPIEA---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53405-1", "uniprot_id": "ISL1_DANRE", "id": "P53405-1", "name": "Insulin gene enhancer protein isl-1", "aln": "-------------------------------------MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALRED-GLFCRADH-DVVERA----TMGAGDPLSPLHPARP-------LQMAAEPISARQPALRPHVHKQPE----------KTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMK-QLQQQQPNDKTNIQGMTGTPMVATSPERHDGGLQANQVEVQSYQPPWKVLSDFALQSDID--------QPAFQQLVNFSEGGPGS-------------------------------------------------------NSTGSEVASMSS----QLPDTPNSMVASPIEA---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50480-1", "uniprot_id": "ISL2_RAT", "id": "P50480-1", "name": "Insulin gene enhancer protein ISL-2", "aln": "--MVDI-------------------------IFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREH-ELLCRADHGLLLERA----AAGSPRSPGPLPGTPP-------GLHLPDAGSGQQVSLRTHVHKQAE----------KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMK-QLQQQQHSDKASLQGLTGTLLVAGSPSAHENAVQGSAVEVQTYQPPWKALSEFALQSDLD--------QPAFQQLVSFSESGSLG-------------------------------------------------------NSSGSDVTSLSS----QLPDTPNSMVPSPVET---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXV0-1", "uniprot_id": "ISL2_MOUSE", "id": "Q9CXV0-1", "name": "Insulin gene enhancer protein ISL-2", "aln": "--MVDI-------------------------IFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAQCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREH-ELLCRADHGLLLERA----AAGSPRSPGPLPGAR--------GLHLPDAGSGRQPSLRTHVHKQAE----------KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMK-QLQQQQHSDKASLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQSDLD--------QPAFQQLVSFSESGSLG-------------------------------------------------------NSSGSDVTSLSS----QLPDTPNSMVPSPVET---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A47-1", "uniprot_id": "ISL2_HUMAN", "id": "Q96A47-1", "name": "Insulin gene enhancer protein ISL-2", "aln": "--MVDI-------------------------IFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREH-ELLCRADHGLLLERA----AAGSPRSPGPLPGAR--------GLHLPDAGSGRQPALRPHVHKQTE----------KTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMK-QLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQSDLD--------QPAFQQLVSFSESGSLG-------------------------------------------------------NSSGSDVTSLSS----QLPDTPNSMVPSPVET---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53406-1", "uniprot_id": "ISL2A_DANRE", "id": "P53406-1", "name": "Insulin gene enhancer protein isl-2a", "aln": "--MVDI-------------------------LPHPSFLGDMGDHSKKKSGIAMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDE-ELLCRADHGLLMERA----SAGSPISPGNIHSSR--------PLHIPEPVPVRQPPHRNHVHKQSE----------KTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMK-QLQQQQHNDKTNLQGLTGTPLVAGSPIRHDTTVQGNPVEVQTYQPPWKALSEFALQSDLD--------QPAFQQLVSFSESGSLG-------------------------------------------------------NSSGSDVTSLSS----QLPDTPNSMVPSPVET---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53407-1", "uniprot_id": "ISL2B_DANRE", "id": "P53407-1", "name": "Insulin gene enhancer protein isl-2b", "aln": "--MVDI-------------------------IFSSSFLDDMGDHSKKKSGLAMCVGCGSQIHDQYILRVSPDLEWHAACLKCVECNQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCTLGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSVRDE-ELLCRADHGLALERG----PGGSPLSPGNIHTRG--------LHMAADPVSVRQTPHRNHVHKQSE----------KTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMK-QLQQQ-HGDKTNLQGMTGTALVAGSPIRHNPSVPGHPVDVQAYQPPWKALSEFALQSDLD--------QPAFQQLVSFSESGSLG-------------------------------------------------------NSSGSDVTSLSS----QLPDTPNSMVPSPVET---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ37-1", "uniprot_id": "Q9VJ37_DROME", "id": "Q9VJ37-1", "name": "Insulin gene enhancer protein ISL-1", "aln": "MVMAEIGGHLAHQLPLHNHNHNQTGLQPSLVMNHHLDLDCHGHDVIKKQRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNGMPILPPHPHSHPAQGPPHQHPPPPGGPHNHQNQQPNQQPGGSSLDSGITSHHHPDSTDSYVTYLESDDKSKLALTPSSSSSASAGTSISSPPSGVGAGGGGAVGGGSGVLGLGVVANQSATEQLMQMLQKVTGSASPASHAVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *. ** : *****.*****:****:************ ** *:***:****************:**:* ** :* .*...*:****: .::*:***** .*:*:*:*****::*: * *: ** : . . .: . . : .: . : . **. . *.******************* *****************.*******************::* ** *:**: . * . .: * ::* ** *: : ::**:******.**:***::*:* *******. .. . :*:.* *: :.* :*. **.* .:. : ", "identical_positions": 182, "similar_positions": 84, "identity": "34.08%" }, { "cls_id": "homologset.agr.FB:FBgn0003900", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPJ1-1", "uniprot_id": "Q9EPJ1_RAT", "id": "Q9EPJ1-1", "name": "Twist-related protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQDVSSSPVSPADDSLSNS---------EEEPDRQQPASGKRGARKRRSSR----RSAGGSAGPGGATGGGIGGGDEPGSPAQGKRGKKSA----------------------GGGGG---AGGGGGGGGSSSGGGSP------------------QSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------ELDSKMASCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26687-1", "uniprot_id": "TWST1_MOUSE", "id": "P26687-1", "name": "Twist-related protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQDVSSSPVSPADDSLSNS---------EEEPDRQQPASGKRGARKRRSSR----RSAGGSAGPGGATGGGIGGGDEPGSPAQGKRGKKSA----------------------GGGGGGGAGGGGGGGGGSSSGGGSP------------------QSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------ELDSKMASCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15672-1", "uniprot_id": "TWST1_HUMAN", "id": "Q15672-1", "name": "Twist-related protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQDVSSSPVSPADDSLSNS---------EEEPDRQQPPSGKRGGRKRRSSR----RSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSA----------------------GCGGG----GGAGGGGGSSSGGGSP------------------QSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------ELDSKMASCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WVJ9-1", "uniprot_id": "TWST2_HUMAN", "id": "Q8WVJ9-1", "name": "Twist-related protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGSSSPVSPVD-SLGTS---------EEELERQP----KRFGRKRRYSK----KSS------------------EDGSPTPGKRGKK--------------------------------------------GSPSA------------------QSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------EMDNKMTSCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97831-1", "uniprot_id": "TWST2_RAT", "id": "P97831-1", "name": "Twist-related protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGSSSPVSPVD-SLGTS---------EEELERQP----KRFGRKRRYSK----KSS------------------EDGSPTPGKRGKK--------------------------------------------GSPSA------------------QSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------EMDNKMTSCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D030-1", "uniprot_id": "TWST2_MOUSE", "id": "Q9D030-1", "name": "Twist-related protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGSSSPVSPVD-SLGTS---------EEELERQP----KRFGRKRRYSK----KSS------------------EDGSPTPGKRGKK--------------------------------------------GSPSA------------------QSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------EMDNKMTSCSY-----------------------------VAHERLSYAYSVWRMEGAWSMSASH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10627-1", "uniprot_id": "TWIST_DROME", "id": "P10627-1", "name": "Protein twist", "aln": "MMSARSVSPKVLLDISYKPTLPNIMELQNNVIKLIQVEQQAYMQSGYQLQHQQQHLHSHQHHQQHHQQQHAQYAPLPSEYAAYGITELEDTDYNIPSNEVLSTSSNQSAQSTSLELNNNNTSSNTNSSGNNPSGFDGQASSGSSWNEHGKRARSSGDYDCQTGGSLVMQPEHKKLIHQQQQQQQQHQQQIYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFDFPDEELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLSYLFGVWRMEGDAQHQKA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :*: .* * .* ** ::: .::: *: :.. * .*: . .*. *. : :. :*:..**::*************:** :*::*******************:****** ::*.*. :: : :..:* :. *:*** :.****** . . : ", "identical_positions": 68, "similar_positions": 57, "identity": "13.85%" }, { "cls_id": "homologset.agr.FB:FBgn0003941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62987-1", "uniprot_id": "RL40_HUMAN", "id": "P62987-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62984-1", "uniprot_id": "RL40_MOUSE", "id": "P62984-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62986-1", "uniprot_id": "RL40_RAT", "id": "P62986-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18101-1", "uniprot_id": "RL40_DROME", "id": "P18101-1", "name": "Ubiquitin-ribosomal protein eL40 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRILAQKYNCDKMICRKCYARLHPRATNCRKKKCGHTNNLRPKKKLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CH08-1", "uniprot_id": "RL40A_YEAST", "id": "P0CH08-1", "name": "Ubiquitin-ribosomal protein eL40A fusion protein", "aln": "MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CH09-1", "uniprot_id": "RL40B_YEAST", "id": "P0CH09-1", "name": "Ubiquitin-ribosomal protein eL40B fusion protein", "aln": "MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************.****:***:******************************************************: **.****** :******** ***.****:******:******:*", "identical_positions": 115, "similar_positions": 10, "identity": "89.84%" }, { "cls_id": "homologset.agr.FB:FBgn0003942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LU69-1", "uniprot_id": "F1LU69_RAT", "id": "F1LU69-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MQIFVKTLIGKTIMLEVEPSDTIENVKAQIQDEEGTPPDQQRLTFAGKQLEGGRTLSDYNVQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLA------VDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62983-1", "uniprot_id": "RS27A_MOUSE", "id": "P62983-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62982-1", "uniprot_id": "RS27A_RAT", "id": "P62982-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A0J6-1", "uniprot_id": "D4A0J6_RAT", "id": "D4A0J6-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MKIFVTTLTGKTITLQFEPSGTTENVKAKIQDKEGIPPEEQRLVFAGEQREDGCTLSDYNIQKEATLHLGLRLHGGAKERKK-SYPTPKKRKHKRTKVKLAVLKYYKVDENGKISRLRRECPSDEGGAGVVMGSHFDRHYCGKCCLTYCFNKPEDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62979-1", "uniprot_id": "RS27A_HUMAN", "id": "P62979-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHFDRHYCGKCCLTYCFNKPEDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15357-1", "uniprot_id": "RS27A_DROME", "id": "P15357-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKNYSTPKKIKHKRKKVKLAVLKYYKVDENGKIHRLRRECPGENCGAGVFMAAHEDRHYCGKCNLTFVFSKPEEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05759-1", "uniprot_id": "RS31_YEAST", "id": "P05759-1", "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "aln": "MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKVYTTPKKIKHKHKKVKLAVLSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:***.** **** *:.*.*.* :***::***:** **::*** ***:* *.* ******:***:**** ***:**.*:*** *.**** ***:.***** ** :**: :*****.. ****.:. * ** ***** .: .. ", "identical_positions": 89, "similar_positions": 34, "identity": "57.05%" }, { "cls_id": "homologset.agr.FB:FBgn0003943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CG69-1", "uniprot_id": "UBIQP_DROME", "id": "P0CG69-1", "name": "Polyubiquitin", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIQA-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q63429-1", "uniprot_id": "UBC_RAT", "id": "Q63429-1", "name": "Polyubiquitin-C", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSVNTKKVKQEDTRTFLTTVSRKSPSCACSWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CG48-1", "uniprot_id": "UBC_HUMAN", "id": "P0CG48-1", "name": "Polyubiquitin-C", "aln": "----------------------------------------------------------------------------MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG50-1", "uniprot_id": "UBC_MOUSE", "id": "P0CG50-1", "name": "Polyubiquitin-C", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSVTTKKVKQ----------------------EDRRTFLTT-VSKKSPPCACSWV-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CG63-1", "uniprot_id": "UBI4P_YEAST", "id": "P0CG63-1", "name": "Polyubiquitin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******************.****:***:******************************************************************.****:***:******************************************************************.****:***:******************************************************************.****:***:******************************************************************.****:***:************************************************ ", "identical_positions": 365, "similar_positions": 15, "identity": "45.06%" }, { "cls_id": "homologset.agr.FB:FBgn0003961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09118-1", "uniprot_id": "URIC_RAT", "id": "P09118-1", "name": "Uricase", "aln": "------------------MAHYHDDYGKNDEVEFVRTGYGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLAKFKGIKSIETFAMNICEHFLSSFSHVTRAHVYVEEVPWKRFE------------KNGVK-------------HVHAFIHTPTGTHFCDVEQVRNGP-PIIHSGIKDLKVLKTTQSGFEGFIKDQFTTLPEVKDRCFATQVYCKWRYQ-NRDVDFEATWGAVRDIVLKKFAGPYDRGEYSPSVQKTLYDIQVLTLSQLPEIEDMEISLPNIHYFNIDMS---KMGLINKEEVLLPLDNPYGKITGTVRRK-LPSRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25688-1", "uniprot_id": "URIC_MOUSE", "id": "P25688-1", "name": "Uricase", "aln": "------------------MAHYHDNYGKNDEVEFVRTGYGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLAKLRGIRNIETFAMNICEHFLSSFNHVTRAHVYVEEVPWKRFE------------KNGIK-------------HVHAFIHTPTGTHFCEVEQMRNGP-PVIHSGIKDLKVLKTTQSGFEGFLKDQFTTLPEVKDRCFATQVYCKWRYQ-RRDVDFEAIWGAVRDIVLQKFAGPYDKGEYSPSVQKTLYDIQVLSLSQLPEIEDMEISLPNIHYFNIDMS---KMGLINKEEVLLPLDNPYGKITGTVKRK-LPSRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DG85-1", "uniprot_id": "URIC_DANRE", "id": "Q6DG85-1", "name": "Uricase", "aln": "------------------MATTS-----NQNVEFVRTGYGKNMVKVLHIRREGNHHHIIELIANVQLTLKTRKDYLTGDNSDIIPTDTVKNTVHALAKLKGIKSIESFALDICEHFLTAFNHVTRVKVNIDEVPWKRLE------------KNGVE-------------HNHAFIHCPEALRFCEAEQYLSKT-PVVHSGLKDMKVLKTTQTGFEGFLRDRFTTLTDAKDRFFCTSVYARWRYN-TINVAFDAAWKAVKDTVIQKFAGPYDRGEYSPSVQKTLYDTQLLVLDRIPEVEEIEIIMPNQHYFVIDMT---KIGLSNKDEVYLPLDNPSGNITGTVCRK-PRARM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16163-1", "uniprot_id": "URIC_DROME", "id": "P16163-1", "name": "Uricase", "aln": "MFATPLRQPAAANHQTPKNSAGMDEHGKPYQYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQKNTVYLLAKKHGIESPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQEETRTNVNGKCENGVQGNCDFSSIDNRSLHNHAFIFTPTALHYCDVVIRRTDPKQTVITGIKGLRVLKTTQSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWEYSDTENLDFLRAWQTVKNIIIRNFAGDPQVGVSSPSVQHTLYLSERQVLDVLPQVSVISMTMPNKHYFNFDTKPFQKIAPGDNNEVFIPVDKPHGTIYAQLARKNINSHL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:. ****: *****: *:* * * *. ...:*.* ::*** *:****:.**: ****: *** :**.. *.**: :..**:. :.** ..:* :: **:*. :**:: * ****. * . ::*:. . . : :*:*.::******:.* .*:.*.* :*.: ** *.* * . *.*. :: * * :*:: ::::*** : * *****:*** : *. :*::. :.: :** *** :* . *:. :::** :*:*:* *.* . : ** :::", "identical_positions": 109, "similar_positions": 106, "identity": "30.97%" }, { "cls_id": "homologset.agr.FB:FBgn0003963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0R1-1", "uniprot_id": "D4A0R1_RAT", "id": "D4A0R1-1", "name": "Zinc finger protein ZFPM2", "aln": "MSRRKQSKPRQIKRPLEDAIEDEEEE----CPVEEADVIAKGDFPLEESFPTGFESENLSCEEVEFFCNKGDDEGIQEPAESDGDSHSDKPGQPGVETDDWDGPGELEVFQRDGERKIQSRQQLPVGTTWGPFAGKMDLNNNS--LKTKAQVSMVLTAGPKWLLDVTWQGVEDSKNNCIVYSKGGQLWCTTTKAISEG-EELIAFVVDFDSRLQTASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGRQREAAP---VSEENEDSTHQISSLCPFPQCTKSFSNARALEMHLTSHSG-------VKMEEFLPPGASLKCTVCSYTADS------------VINFHQHLFSHLTQAAFRCNHCHFG--FQTQRELLQHQELHVPGGKLPRESDMEHSPSGTEDS-----LQPATDLLARSDLSQSQKAMPTKDASSDTELDKCEKKTQLFLTNQRPE---MQPAANK-----QNFSYTKIKSEPSSPRLASSPVQPNLGPSFPVG-------PFLSQFAFPQDIT-----MVPQASEILAKMSELVHRRLRHGSS----SYPPVIYSPLMPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKIPEALSPNTGQTSINLLNPAAHPPDPENPLLQTSCINSSTVLDLIGPNGKGHEKDFSTQAKKLPTSNNNDDKINGKPVDVKNPSGPLVDGESDPNK-------------TTCEACNITFSRHETYMVHKQYYCATRHDPPL----KRSASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLSNPCSSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLAINKCVPVPKCDTTHSSVSCLEMDVPIDLSKKCLSQSERTTASPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERNSPEVSFERNMIKCEKNGNPKQPSPNGN---LFSSHLATLQGLKVFSEAAQLIATKEENKHLFLPQCLYPGAIKKTKGADQLSPYYGIKPSDYIAGSLVIHNTDVEQNTNTENESPKGQASSNGCAVPKKDSLPLLPKNRGMVIVNGGLKQDERPTANPQQENISQNAQHEDGHKSPSWISENPLAANENVSPGIPCAEEQLSSIAKGVNGSTQAPSSGKYCRLCDIQFNNLSNFITHKKFYCSSHAAEHVK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCH7-1", "uniprot_id": "FOG2_MOUSE", "id": "Q8CCH7-1", "name": "Zinc finger protein ZFPM2", "aln": "MSRRKQSKPRQIKRPLEDAIDDEEEE----CPVEEAEVISKGDFPLEGSFPAGFEPENLSCEDVEFFCNKGDDEGIQEPAESDGDSHSDKPGQPGVETDDWDGPGELEVFQRDGERKIQSRQQLPVGTTWGPFAGKMDLNNNS--LKTKAQVPMVLTAGPKWLLDVTWQGVEDSKNNCIVYSKGGQLWCTTTKAISEG-EELVAFVVDFDSRLQAASHMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGRQREAAP---VSEENEDNSHQVSSLCPFPQCTKSFSNARALEMHLNSHSG-------VKMEEFLPPGASLKCTVCSYTADS------------VINFHQHLFSHLTQAAFRCNHCHFG--FQTQRELLQHQELHVPSGKLPRESDMEHSPSGTEDS-----LQPATDLLARSDLSQSQKAMPTKDASSDTELDKCEKKTQLFLTNQRPE---IQPAANK-----QNFSYTKIKSEPSSPRLASSPVQPNIGPSFPVG-------PFLSQFAFPQDIT-----MVPQASEILAKMSELVHRRLRHGSS----SYPPVIYSPLMPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEAVSPNTGQTSINLLNPAAHSSDPENPLLQTSCINSSTVLDLIGPNGKGHEKDFSTQVKKLPTSNSSDDKINGKPVDVKNPSGPLVDGESDPNK-------------TTCEACNITFSRHETYMVHKQYYCATRHDPPL----KRSASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLSNPCSSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLAMNKCVPVPKCDTTHSNVSCLEMDVPIDLSKKCLSQSERTTASPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERSSPEVSFERNMIKCEKNGNPKQPSPNGN---LFSSHLATLQGLKVFSEAAQLIATKEENKHLFLPQCLYPGAIKKTKGADQLSPYYGIKPSDYIASSLVIHNTDVEQSTNTENESPKGQASSNGCAVPKKDSLPLLPKNRGMVIVNGGLKQDERPTANPQQENISQNTQHEDGHKSPSWISENPLAANENVSPGIPCAEEQLSSIAKGVNGASQAPSSGKYCRLCDIQFNNLSNFITHKKFYCSSHAAEHVK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WW38-1", "uniprot_id": "FOG2_HUMAN", "id": "Q8WW38-1", "name": "Zinc finger protein ZFPM2", "aln": "MSRRKQSKPRQIKRPLEDAIEDEEEE----CPSEETDIISKGDFPLEESFSTEFGPENLSCEEVEYFCNKGDDEGIQETAESDGDTQSEKPGQPGVETDDWDGPGELEVFQKDGERKIQSRQQLPVGTTWGPFPGKMDLNNNS--LKTKAQVPMVLTAGPKWLLDVTWQGVEDNKNNCIVYSKGGQLWCTTTKAISEG-EELIAFVVDFDSRLQAASQMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGRQREAAP---VSEENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSG-------VKMEEFLPPGASLKCTVCSYTADS------------VINFHQHLFSHLTQAAFRCNHCHFG--FQTQRELLQHQELHVPSGKLPRESDMEHSPSATEDS-----LQPATDLLTRSELPQSQKAMQTKDASSDTELDKCEKKTQLFLTNQRPE---IQPTTNK-----QSFSYTKIKSEPSSPRLASSPVQPNIGPSFPVG-------PFLSQFSFPQDIT-----MVPQASEILAKMSELVHRRLRHGSS----SYPPVIYSPLMPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLDLIGPNGKGHDKDFSTQTKKLSTSSNNDDKINGKPVDVKNPSVPLVDGESDPNK-------------TTCEACNITFSRHETYMVHKQYYCATRHDPPL----KRSASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSKCDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERNSPDVSYERSIIKCEKNGNLKQPSPNGN---LFSSHLATLQGLKVFSEAAQLIATKEENRHLFLPQCLYPGAIKKAKGADQLSPYYGIKPSDYISGSLVIHNTDIEQSRNAENESPKGQASSNGCAALKKDSLPLLPKNRGMVIVNGGLKQDERPAANPQQENISQNPQHEDDHKSPSWISENPLAANENVSPGIPSAEEQLSSIAKGVNGSSQAPTSGKYCRLCDIQFNNLSNFITHKKFYCSSHAAEHVK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A168-1", "uniprot_id": "D4A168_RAT", "id": "D4A168-1", "name": "", "aln": "MSRRKQSNPRQIKRSLRDMEAGEEAKGMDISPMEQEATAPEAPAIEEPPSPPREDVSLPTVSAPPESPDDPEDVEGQELEMRPQDEKKEEKEEESAMASPWSGPEELELALQDGQRCVRARLSLTEGLSWGPFYGSIQTRALSPEREEPGPALT-LMVDESCWLRMLPQALTEEEANSEIYRKDDALWCRVTKAVPSGGLLHVLLVAEPHGTPKHPVQ-EPEEAGSSGPVHTDIQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQRASSP-VSATEEKPKETYPNERICPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSAWPTGVCHNCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPSDSLTGFQQ-HSLRHSPLVPADK--APTPSSGLDSKALAEVTNGETRVPP--QNGGSSESPAAPRTIKVEAAEEPE---AARASGPGEPGPQAPSRTPSPHSPNPVRVKAELSSPTPGSSPGPGELTMAGTLFLPQYVFGPDAGTTTVPAAPQASEILAKMSELVHNRLQQGAGSSGVAGTPTGLFPGT-KGATCFECEITFNNINNFYVHKRLYCSG-----RRAPEDPPAVRRPKAATGSAR--------APAGVAAEPDPPRSSP------------GPGPREEEASGATTPEAETAGRGSEG--------SQSPGSSVDDAEDDPSR-------------TLCEACNIRFSRHETYTVHKRYYCASRHDPPP----RRPPVPTPAPGP----------------AAPALTAP--PVRTRRRRKLYELPAAGAPPP-AAGPAPVP--------VVSSPTAELPSSPRPASASAGPAPTPSPGPVPDGPIDLSKRPRRQTPDTPTALPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPLR-------TTALCP------------------YCPPNGRVRG----------------------------------DLVEHLRQAHGLQVAKPAASPGAEPRTAAE---------------RAPRDS--------PDGRAPR-----------------------------SPSPAPENTPSDQA-----DQGARTSCKGPPAPAPAPG-------------------------GGGGHRYCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35615-1", "uniprot_id": "FOG1_MOUSE", "id": "O35615-1", "name": "Zinc finger protein ZFPM1", "aln": "MSRRKQSNPRQIKRSLRDMEAGEEAKAMDSSPKEQEAPDPEAPAIEEPPSPPREDVSPPAVPAPPESPEDPEDMEGQELEMRPQDEEKEEKEEEAAMASPWSGPEELELALQDGQRCVRARLSLTEGLSWGPFYGSIQTRALSPEREEPGPAVT-LMVDESCWLRMLPQVLTEEAANSEIYRKDDALWCRVTKVVPSGGLLYVRLVTEPHGAPRHPVQ-EPVEPGGLAPVHTDIQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQRAGSP-VSATEEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLS----GVCHNCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGFQQ-HSLMHSPLVPADK--APTPSSGLDSK--AEVTNGETRVPP--QNGGSSESPAAPRTIKVEAAEEPE---ATRASGPGEPGPQAPSRTPSPHSPNPVRVKTELSSPTPGSSPGPGELTMAGTLFLPQYVFSPDAGTTTVPTAPQASEILAKMSELVHNRLQQGAGSSGAAGTPTGLFSGT-KGATCFECEITFNNINNFYVHKRLYCSG-----RRAPEDPPTVRRPKAATGPAR--------APAGAAAEPDPSRSSP------------GPGPREEEASGTTTPEAEAAGRGSEG--------SQSPGSSVDDAEDDPSR-------------TLCEACNIRFSRHETYTVHKRYYCASRHDPPP----RRPPAPTTAPGP----------------AAPALTAP--PVRTRRRRKLYELPAAGAPPP-AAGPAPVP--------VVPSPTAELPSSPRPGSASAGPAPALSPSPVPDGPIDLSKRPRRQSPDAPTALPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPLR-------TTALCP------------------YCPPNGRVRG----------------------------------DLVEHLRQAHGLQVAKPAASPGAEPRTPAE---------------RAPRDS--------PDGRAPR-----------------------------SPSPAPENTPSDPA-----DQGARTPSKGPPAPAPAPG-------------------------GGGGHRYCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX07-1", "uniprot_id": "FOG1_HUMAN", "id": "Q8IX07-1", "name": "Zinc finger protein ZFPM1", "aln": "MSRRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAP------SPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEP---------GSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAH-DLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLS----GVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPE---AAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDA-------APPASEILAKMSELVHSRLQQGAG-AGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSG-----RRAPEDAPAARRPKAPPGPAR--------APPGQPAEPDAPRSSP------------GPGAREEGAGGAATPEDGAGGRGSEG--------SQSPGSSVDDAEDDPSR-------------TLCEACNIRFSRHETYTVHKRYYCASRHDPPP----RRPAAPPGPPGP----------------AAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAP--------ESPRPGSGSGSGP-------GLAPARSPGPAADGPIDLSKKPRRPLPGAP--APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALG--LPAAACP------------------YCPPNGPVRG----------------------------------DLLEHFRLAHGLLLGAPLAGPGVEARTPAD---------------RGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPP-------------PSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPN-----------------------------GNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPQ6-1", "uniprot_id": "USH_DROME", "id": "Q9VPQ6-1", "name": "Zinc finger protein ush", "aln": "------MLSSNTRGDCSDTAEEMTVD-----SRDSKDLSAQDIGEQKQQQMEDQLEDQLNDSRDPQNNNNNIDDDADEDAEFEEPEKANPQQDQDLGETEMEQEHDLQQEDLQQELPANSPSTPPRSPSSPQLIPKLEQPATPPSEPEASPCPSPSPCPTPKYPKVRLNALLASDP-----------------ALKPDAKELTLPDSRLLAPPPLVKPDTQAQPEVAEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHR-IKDTDEAGSDKSGAGGSGATAGDAAGLTGGSTEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLAGLPSLLQNGIAPPGVTPNPMEDSSSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGAGSGPGSAGGSIGVSAQAATPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATPHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALVGATLEPERPSAPSSAAEATEAKSSPPEPKRKEAGLTRESAPLDLSLRRSPITLNSLSLRQR--QLRNALLDVEEVLLAGVGTGKENVETPRGGGSVTPEQIVCAP---SLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFPPASLPAQTSSGNPGSGGSAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGASEVDVKSAVSPSIAGAGGLGAGAAEAASSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAVAAP--------AATPTDPGQLGMPKEKCGKCKTLHEIGLPCPPPVANPLAAPTVNPQPATNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEELYMTCIFEEDASALSQELVTPTGASTTTGHDSMDHPSQMFNCDYCNYVSTYKGNVLRHMKLMHPHVAINSPSISPDTRDQD-------------VTSNPTTNQHSNSDVSNGEAPSFHIKSEPLDPPPTVN-----------LVHENNNSPIATPHIKAEPIEVGADAAPGGLVPPMTSPLGNSSS--------------VAAAAAAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGVAVGLGIGGLVGGHGQQKNKENLQEAAI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * . :. .: . : :* . . :*: : : .: . . : : .:: . . : : : . . : ::: ..:* .::: :: : *. * .* . : ... .: : * . .** * . :*: *: *. : : . . * .: : .. * . * .. : . . . : .. : : . : : .. .. . . . . . :: : * :. * . *. : :: . .. . :: *: :*. .. .: . . * . *. . . . . : . .... . ..... : * *** *.::*.* .**::**::* : :.. . . .* : : * * . . *: : .... :: : :* : : * *. . . . : : : . . : . .... . :. : . . . . . :** *:* *. :..:::**::**..:. . ", "identical_positions": 52, "similar_positions": 213, "identity": "4.09%" }, { "cls_id": "homologset.agr.FB:FBgn0003964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49743-1", "uniprot_id": "RXRB_RAT", "id": "P49743-1", "name": "Retinoic acid receptor RXR-beta", "aln": "-----------------------------------------------------------------GEAGRDGMGDTGRDSRSPDSSSPNPLSQGIPPSSPPGPPHTPS----------APPPP-MPPPPLGSPFPVISS-SMGSP--GLPPPAPPGFSGPVSSPQINSTVSLPG-GGSGPPEDVKPPVLGVRGLHCPPPPGGPGA----GKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQ--------EERQRGKDK-DGDGDGA---------------------------------------GGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28704-1", "uniprot_id": "RXRB_MOUSE", "id": "P28704-1", "name": "Retinoic acid receptor RXR-beta", "aln": "MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAA---GEQQALEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPS----------APPPP-MPPPPLGSPFPVISS-SMGSP--GLPPPAPPGFSGPVSSPQINSTVSLPG-GGSGPPEDVKPPVLGVRGLHCPPPPGGPGA----GKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQ--------EERQRGKDK-DGDGDGA---------------------------------------GGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28702-1", "uniprot_id": "RXRB_HUMAN", "id": "P28702-1", "name": "Retinoic acid receptor RXR-beta", "aln": "MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPP-MPPPPLGSPFPVISS-SMGSP--GLPPPAPPGFSGPVSSPQINSTVSLPG-GGSGPPEDVKPPVLGVRGLHCPPPPGGPGA----GKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQ--------EERQRGKDK-DGDGEGA---------------------------------------GGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYN5-1", "uniprot_id": "RXRBA_DANRE", "id": "Q7SYN5-1", "name": "Retinoic acid receptor RXR-beta-A", "aln": "--------------------------------------------------------------------MGDSRDSRSPDSSSVSSPPSGQRSPPLAPSAAAMTSLPPI----------TSAVN-SPISSMGSPFSVISS-SLGSP--CLPGTPSVGY-GPISSPQINSTVSMSGLHAVSSSDDVKPP-FGLKPLSSH-SPGPMVS----QKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLSYTCRDNKDCLVDKRQRNRCQYCRYQKCLAMGMKREVVQDERQRSVQEERQRNKER-DGEVESS---------------------------------------SAANEEMPVEKILEAEMAVEQKTELHADGSSG----GSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSELSLDDQVILLRAGWNELLIASFSHRSITVKDG---------------------------ILLATGLHVHRNSAHSAGVGAIFDRESAHNAEVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIILFNPDAKGLSSPSEVELLREKVYASLEAYCKQRYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90417-1", "uniprot_id": "RXRBB_DANRE", "id": "Q90417-1", "name": "Retinoic acid receptor RXR-beta-B", "aln": "-----------------------------------------------------------------------------------------------------MNSLPPS----------TSAVS-SPVSSVDSPLSAVSS-SIGSP--GVPGTPSIGY-GPISNSQINSSMSVSRLHAVSSSDDVKPP-FGLKSVS---GSGPMLS----QKRMCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLSYTCRDNKECLVDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQKNKER-DGDYECS---------------------------------------SSANEEMPVEKILEAETAVEHRTDLHSDATG-------SPNDP-----VTNICQAADKQLFTLVEWAKRVPHFSDVPLDDQVILLRAGWNELLIAAFSHRSISVKDE---------------------------ILLATGLHVPKESTHNLGVEAFFDRESSHSAEVGALFDRVLTELVCKMRDMQMDKTELGCLRAIVLFNPDAKGLTSSSEVELLREKVYASLESYCKQKYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGNTPIDTFLMEMLESPH---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19793-1", "uniprot_id": "RXRA_HUMAN", "id": "P19793-1", "name": "Retinoic acid receptor RXR-alpha", "aln": "-----------------------------------------------------MDTKHFLPLDFSTQVN-SSLTSPTGRGSMAAPSLHPSLGPGIGS----PGQLHSP----------ISTLS-SPINGMGPPFSVISS-PMGPHSMSVPTTPTLGF-S-TGSPQLSS-----PMNPVSSSEDIKPP-LGLNGVLKVPAHPSGNM-ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRGKDRNENEVEST---------------------------------------SSANEDMPVERILEAELAVEPKTETYVEANMGL--NPSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28700-1", "uniprot_id": "RXRA_MOUSE", "id": "P28700-1", "name": "Retinoic acid receptor RXR-alpha", "aln": "-----------------------------------------------------MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSP----------ISTLS-SPINGMGPPFSVISS-PMGPHSMSVPTTPTLGF-G-TGSPQLNS-----PMNPVSSTEDIKPP-LGLNGVLKVPAHPSGNM-ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRGKDRNENEVEST---------------------------------------SSANEDMPVEKILEAELAVEPKTETYVEANMGL--NPSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05343-1", "uniprot_id": "RXRA_RAT", "id": "Q05343-1", "name": "Retinoic acid receptor RXR-alpha", "aln": "-----------------------------------------------------MDTKHFLPLDFSTQVNSSSLSSPTGRGSMAAPSLHPSLGPGLGSPLGSPGQLHSP----------ISTLS-SPINGMGPPFSVISS-PMGPHSMSVPTTPTLGF-E-TGSPQLNS-----PMNPVSSSEDIKPP-LGLNGVLKVPAHPSGNM-SSFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRGKDRNENEVEST---------------------------------------SSANEDMPVEKILEAELAVEPKTETYVEANMGL--NPSSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQTT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2T929-1", "uniprot_id": "RXRAA_DANRE", "id": "A2T929-1", "name": "Retinoic acid receptor RXR-alpha-A", "aln": "-----------------------------------------------------MHPSLLSPT---------------------------SLGP--------SGSLHSP----------ISTLS-SPMNGLGSPFSVISS-PMGPHSMASPG---VGY-GPSISPQLNS-----HMNSVSSSEDIKPP-LGLNGVMKVPAQPSGTP-LSLTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCVIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRAKERSENEVEST---------------------------------------SSANEDMPVEKILEAELAVEPKTETYIETNVPM--PSNSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDG---------------------------ILLATGLHVHRN--------------SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPGEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90415-1", "uniprot_id": "RXRAB_DANRE", "id": "Q90415-1", "name": "Retinoic acid receptor RXR-alpha-B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MPVPEQ--------KQTVQLSS-----PMNAVSSSEDIKPP-LGLNGVMKVPAHRIGTLSLSLTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCMIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRAKERSEAEFG-----------------------------------------GCANEDMPVEKILEAELAVEPKTETYVEANLSP--SANSPNDP-----VTNICQAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSIAVKDG---------------------------ILLATGLHVHRN--------------SAHTAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPSEVEALRERVYASLEAYCKHKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQIT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5BJR8-1", "uniprot_id": "RXRG_RAT", "id": "Q5BJR8-1", "name": "Retinoic acid receptor RXR-gamma", "aln": "-----------------------------------------------------MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRT----------LSAVG-TPLNALGSPYRVITS-AMGPPSGALAAPPGINL-VVPPSSQLN------VVNSVSSSEDIKPL-PGLPGIGN-MNYPSTSP-GSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQ--------EERQRSRERAESEAECA---------------------------------------STGHEDMPVERILEAELAVEPKTESYGDMSV-----ESSTNDP-----VTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG---------------------------ILLATGLHVHRS--------------SAHSAGVGSIFDRVLTELVSKMKDMRMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28705-1", "uniprot_id": "RXRG_MOUSE", "id": "P28705-1", "name": "Retinoic acid receptor RXR-gamma", "aln": "-----------------------------------------------------MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRT----------LSAVG-TPLNALGSPYRVITS-AMGPPSGALAAPPGINL-VAPPSSQLN------VVNSVSSSEDIKPL-PGLPGIGN-MNYPSTSP-GSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQ--------EERQRSRERAESEAECA---------------------------------------SSSHEDMPVERILEAELAVEPKTESYGDMNV-----ENSTNDP-----VTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG---------------------------ILLATGLHVHRS--------------SAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48443-1", "uniprot_id": "RXRG_HUMAN", "id": "P48443-1", "name": "Retinoic acid receptor RXR-gamma", "aln": "-----------------------------------------------------MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRT----------LSAVG-TPLNALGSPYRVITS-AMGPPSGALAAPPGINL-VAPPSSQLN------VVNSVSSSEDIKPL-PGLPGIGN-MNYPSTSP-GSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQ--------EERQRSRERAESEAECA---------------------------------------TSGHEDMPVERILEAELAVEPKTESYGDMNM-----ENSTNDP-----VTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG---------------------------ILLATGLHVHRS--------------SAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90416-1", "uniprot_id": "RXRGA_DANRE", "id": "Q90416-1", "name": "Retinoic acid receptor RXR-gamma-A", "aln": "-----------------------------------------------------MDNNDTYLHLSSS----------------------LQVAHGHLSSPPSQPPLSSM----------VSHHHPSIINGLGSPYSVITSSSLGSPSASMPTTSNMGY-GALNSPQMN------SLNSVSSSEDIKPP-PGLAGLG---SYPCGSP-GSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYTCRDNKDCQIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRGRERSDNEVDSS---------------------------------------SSFNEEMPVEKILDAELAVEPKTEAYMESSM-----SNSTNDP-----VTNICQAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSVTVKDG---------------------------ILLATGLHVHRS--------------SAHSAGVGSIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDAKGLSNPSEVEALREKVYASLEGYTKHNYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQIT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DHP9-1", "uniprot_id": "RXRGB_DANRE", "id": "Q6DHP9-1", "name": "Retinoic acid receptor RXR-gamma-B", "aln": "-----------------------------------------------------MDTHDTYLHLHSSPLNSSPSQP-----------PVMSSMVGHPSVISSSRPLPSP----------MSTLG-SSMNGLPSPYSVITP-SLSSPSISLPSTPSMGF-NTLNSPQMN------SL-SMNGNEDIKPP-PGLAPLGNMSSYQCTSP-GSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYTCRDIKECLIDKRQRNRCQYCRYQKCLAMGMKREAVQ--------EERQRGKEKSDTEVETT---------------------------------------SRFNEDMPVDKILDAELSVEPKTETYTESSP-----SNSTNDP-----VTNICHAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSITVKDG---------------------------ILLGTGLHVHRS--------------SAHSAGVGSIFNRVLTELVSKMKDMQMDKTELGCLRAIVLFNPDAKGLSNSLEVEALREKVYASLETYTKQKYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQIT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20153-1", "uniprot_id": "USP_DROME", "id": "P20153-1", "name": "Protein ultraspiracle", "aln": "-------------------------------------------------------------------------------MDNCDQDASFRLSHIKEEVKPDISQLNDS-----------NNSSFSPKAESPVPFMQAMSMVHVLPGSNSASSNNNSAGDAQMAQAPNS----AGGSAAAAVQQQYPP-----------NHPLSGS-----KHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQ--------EERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCGDRALTFLRVG--PYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRN--------------SAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPLEELFLEQLEAPPPPGLAMKLE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: * *::*:*****:********************:**** *:**: ::* :*****************. *****.** ****: . .::.:::*::** .* : *. :* *: :*:..:**** :**:*: :***:.:.*:******:*.* ***** .: *: * ::* .: :. *: .* *.::*:*:*:** **: :.:*: **.**:**:*:*** :*:.. *:* **:*** *: : : .:* : ****:***********.*** :***:*:: .: *:: :::* **:* ", "identical_positions": 157, "similar_positions": 100, "identity": "24.45%" }, { "cls_id": "homologset.agr.FB:FBgn0003965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21643-1", "uniprot_id": "T23O_RAT", "id": "P21643-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MSGCPFSGNSVGYTLKNLSMEDNEEDGAQTGVNRASKGGLIYGDYLQLEKILNAQELQSEIKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVMTRMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFEGDYNE-LLLKSEQEQTLLQLVEAWLERTPGLEPHGFNFWGKFEKNILKGLEEEFLKIQAKKDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGSK-AGTGGSSGYYYLRSTVSDRYKVFVDLFNLSSYLVPRHWIPKMNPIIHKFLYTAEYSDSSYFS--SDESD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48776-1", "uniprot_id": "T23O_MOUSE", "id": "P48776-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MSGCPFAGNSVGYTLKNVSMEDNEEDRAQTGVNRASKGGLIYGNYLQLEKILNAQELQSEVKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVIARMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFGGDYNE-LLLKSEQEQTLLQLVEAWLERTPGLEPNGFNFWGKFEKNILKGLEEEFLRIQAKTDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGTK-AGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLVPRHWVPKMNPIIHKFLYTAEYSDSSYFS--SDESD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48775-1", "uniprot_id": "T23O_HUMAN", "id": "P48775-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MSGCPFLGNNFGYTFKKLPVEGSEEDKSQTGVNRASKGGLIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHYRDNFKGEENE-LLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFIRIQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSK-AGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFS--SDESD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MBU6-1", "uniprot_id": "T23OA_DANRE", "id": "A7MBU6-1", "name": "Tryptophan 2,3-dioxygenase A", "aln": "MSGCPYFQRKFLSTSKQH-LKEEENDEAQTGINKASKGGLIYGDYLQLDKIVTSQVLQSELKGNKIHDEHLFIVTHQAYELWFKQVLWELDSVREIFISGHVRDERNMLKVNTRIHRIVMIFRLLLDQFAVLETMTALDFYDFREYLSPASGFQSLQFRLLENKIGVPHNQRVPYNRRHYRDNFRDQESE-LLLHSEQEPTLLQLVEQWLERTPGLEEDGFNFWGKLEKNIFEGLRREKEHIEQKPASERKEEMLAELIKQRDIFLSLFDEKRHDHLVSTGQRRLSYKALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMIGSK-DGTGGSSGYQYLRSTVSDRYKVFVDLFNLATFLIPRDWVPKLDPSEHTFLYMAECCDSSYCS-SSDDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7SY53-1", "uniprot_id": "T23OB_DANRE", "id": "Q7SY53-1", "name": "Tryptophan 2,3-dioxygenase B", "aln": "MSGCPFLGGTLQLLSSNP-RQAEEEDGSQGGVNKAAKGGIIYGDYLQLDKVLNAQVLQSEQKGNKIHDEHLFIVTHQAYELWFKQILWELDSVRDLFIKKHVRDERNMLKVVSRIHRITMIFKLLVDQFAVLETMTALDFFDFREYLSPASGFQSLQFRLLEQKIGVADHLRVPYNRRHYRDNFHGEESE-TLLSSEQEPTLLQLVEQWLERTPGLEKDGFNFWGKLQANIEEGLKREKHQVEKMEDTEVKQELLEDLNKQMETFTALFDSKRHEHLLSKGERRLSYKALQGALMINFYREEPRFQVPFQLLTALMEIDTLMTKWRYNHVCMVHRMIGSK-AGTGGSSGYHYLRSTVSDRYKVFVDLFNLATFLVPRSWVPKLNPNIHKFPYTAECYDSSYNSCSSEDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20351-1", "uniprot_id": "T23O_DROME", "id": "P20351-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MS-CPYAGN--------------GNDHDDSAVPLTTEVGKIYGEYLMLDKLLDAQCMLSEEDKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLD-AEVIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVRYN-QKYSDVFSDEEARNSIRNSEKDPSLLELVQRWLERTPGLEESGFNFWAKFQESVDRFLEAQVQSAMEEPVEKAKNYRLMDIEKRREVYRSIFDPAVHDALVRRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLDETIRKKLINKSV--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **: :* : .: ::: * ***:** *:*:: :* : ** . . :*******:***********:::*:**:*::: .* ** : *:: *::*: :*::**::*..:*****.*** ***:**:************:*:*:** ** ** ::* * * .: . : **:: :**:**: ********* *****.*:: .: . *. : : *: : :: *: : .:** *: *: *:**:*::*****:** ***:****. *.**** **:**:*:******** **:**:*:: ******** *****:*******:*****:::*:** :* :: :. . ", "identical_positions": 182, "similar_positions": 104, "identity": "44.39%" }, { "cls_id": "homologset.agr.FB:FBgn0003969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50904-1", "uniprot_id": "RASA1_RAT", "id": "P50904-1", "name": "Ras GTPase-activating protein 1", "aln": "MMAAEAGSEEGGPATAGTGGA-AATGSSAYPAACR-----VKLPAAPPMAVAPCPGLADTDLAAALGGGAASGSGFLGTGPVSGVLGGAALTG---------GAAAGVAGAAAAGPAGDIALTKGTLSLPAETLGPGGGFPPLPPPPLLPPLGSGLGTVDEGDSLDGPEY-EEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQTNVVNHFRIIAMCG---DYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTN---LRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQ-----IVEGYYLKEPVPMQDQGQVLNDTVDGK---EIYNTIRRKTKDAF----YKNIVKKGYLLK-KGKGKRWKNLYFILE--GSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCS-LRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDD----------------LPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSS------HIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQ--DRTLLASILLKIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMK--------------ATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLAHLLSILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNNTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLTLVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELP--------DTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGVQQHVLKKLLAITELLQQKQNQYTKTNDVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PYG6-1", "uniprot_id": "E9PYG6_MOUSE", "id": "E9PYG6-1", "name": "Ras GTPase-activating protein 1", "aln": "MMAAEAGSEEGGPATAGPGGG-AATGSSAYSAACR-----VKLPAALPVAAAPCPGLADADLVAALGGGAASGSGFLGTGPVAGVLGGAALTG---------SAAAGVAGAAAAGPAGDVAFTKGTLSLPAETLGPGGGFPPLPPPPQLPPLGSGLGTVDEGDSLDGPEY-EEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQTNVVNHFRIIAMCG---DYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTN---LRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQ-----IVEGYYLKEPVPMQDQGQVLNDTVDGK---EIYNTIRRKTKDAF----YKNIVKKGYLLK-KGKGKRWKNLYFILE--GSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCS-LRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDD----------------LPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSS------HIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQ--DRTLLASILLKIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMK--------------ATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLAHLLSILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNNTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLTLVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELP--------DTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGVQQHVLKKLLAITELLQQKQNQYTKTNDIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20936-1", "uniprot_id": "RASA1_HUMAN", "id": "P20936-1", "name": "Ras GTPase-activating protein 1", "aln": "MMAAEAGSEEGGPVTAGAGGGGAAAGSSAYPAVCR-----VKIPAALPVAAAPYPGLVETGVAGTLGGGAALGSEFLGAGSVAGALGGAGLTGGGTAAGVA-GAAAGVAGAAVAGPSGDMALTKLPTSLLAETLGPGGGFPPLPPPPYLPPLGAGLGTVDEGDSLDGPEY-EEEEVAIPLTAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCG---DYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEISFLKGDMFIVHNELEDGWMWVTN---LRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIGDIIDHYRKEQ-----IVEGYYLKEPVPMQDQEQVLNDTVDGK---EIYNTIRRKTKDAF----YKNIVKKGYLLK-KGKGKRWKNLYFILE--GSDAQLIYFESEKRATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCN-LRKSSPGTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDD----------------LPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSS------HIPLKGIEPGSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQ--DRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMK--------------ATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELP--------DTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQYTKTNDVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F372-1", "uniprot_id": "E7F372_DANRE", "id": "E7F372-1", "name": "Ras GTPase-activating protein 1", "aln": "MMATQGGGKEPDPFSMVPRIT-RADGDTHIPACHGQGIQISDLGSALSIHTTVLPPKQPPTVTYSIFGKDPRPGTVMFASKGAGVSAGHVILG----------SFSGVGRGMSDPQHEGAVGWVPSASLSPEMCLAAPSFRPLS-------------IVEEGDTLDVQEIGEDEEIVLTLTAPPPNQWYHGKLDRMIAEERLLQVRAAGSYLIRESDRRPGSFVLSFLSMTNTVSHFRIIAMCG---DYYIGGRRFSSLSDLIGYYSYVSCLLKGEKLISPVAPPEPVEDRRRVRAILPYTKVPETDEISFFKGDTFIVHNELEDGWLWVTN---VRTDEQGLIVEDLVKEVGREEDPHEGKAWFHGKISKQEAYNLLMTVGQVGSFLVRPSDSTPGDYSLYFRTTETIQRFKISPTPSNQFMMGGRYYNSIDDIIEHYRREQ-----IVEGHSLKDALSVQHQEQVLTDIVEGK---EIYNTIRRKTKDAF----YKNIVKKGYILFNKGKGKRWKNLYFILE--GNDSQLIYFESEKRATKPKGLIDLSVCSVYEVHDSMFGRPNCFQIVVQHFSEEQCIFYFAGETPEQAEDWMKCLQTFCNNLRKPVQPCSNKRLRQVSSLFLNVEEAHKLPSKHFTNAYCNIYLNSIQVAKTHPREGQNPVWTEEFIFDD----------------LSSEINRFEISLSNKTKKSKENDILFMCCPLCRLQRGQIIDEWFPLSS------HVPLKNVMPSSLRLRVRYSVEKIMPVEVYSELKELVVLRDLHVVSALAHVCGQ--KRTLLASVLLRIFRHQNQEAQLLRELNDREICAEDEATTLFRATTLASTLMEQYMK--------------ATATPFVHHALKDSILKIMDSRQSCELNPSKLEKNEDVNVNLAHLLSIVSELLEKIFMAAEILPPTLRFIYGCLQKAVEQKWPRNTTMRTRVVSGFVFLRLICPAIVNPRIFNIIADPPSPVASRTLTLVAKAVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMILFLDELGKVSELP--------EPTEHFNTDVARDLAALHQLCVTHLDELRTLSNDRGAQQHVLKKLLAVSELLQQTQGQYSGSSGGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IR23-1", "uniprot_id": "Q8IR23_DROME", "id": "Q8IR23-1", "name": "", "aln": "------------------------------------------------MADLIHLGNIDVVIQKDKPG---SPTGCSDDGNLAGLGG-----------------MTGLGGIMAPG---GIDLGDLAQEL-------------------------------DHDEFDGPHMLNGERPAI--IAPPESEWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTG-INHFRITAVCG---DFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDKKRVVAILPYTKMPETDELSFQKGDIFFVHNDMGDGWLWVTA---HRTGEQGMIFRELVDDLDVSIDPNTVFPWFHPNCTKNEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK-GVRYLMGGRTFECLDAVINRYRKEQ-----IVEGHSLNHPVVNGIQPEFNQQYVVEKAAEKIYATLR-ECRDQIGLKKIKGIKHHGHLNKKSDKTTKWKQLYFALINDGSETQLCFYDNPK-KTKPKGLIDLSCAYLYQCHDSLWERPYCFQIVERALPCLATVTYLCAPSQESYVEWINSLKAQCD-SQLSRAQKKVSRLRELRCLNLHVLEAHRLPFKLVPHPYCSISLNQVKVGKTRVKIAPEPVWEEEFVLDD----------------VPPDVVSLTITLISRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTG------MTPMG--EWGSLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAELCHN--DRVPLATALLRVFRQEKRETELIRMLCQAEVTRENETTTLFRGASLATTLMDLYMR--------------TECSGFLQSAVSETVQRILESKQSAELNPTKMDVNDDACTNAEFLLQILDLVTQSIFTSPDACPRNVRFICSCLQKAVMAKWPTERLVRTRVVSGFIFLRLLCPALLNPRQFGLVSETPPMAATRSLVMVAKCLQNLANLIEFGGKEQYMEVVNPFILKNKERMIVFLDQLSSVNDPNQPLGMFVEQSTNLNSQDTGRELATLHHICVSHSQELHELSN-----ILSIKKLVTVTDMLTKHKLKYREMIS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33314-1", "uniprot_id": "BUD2_YEAST", "id": "P33314-1", "name": "Inhibitory regulator protein BUD2/CLA2", "aln": "---MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPIEVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRS-RDLDNGANSGIKFNSIIPKAEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKSSNKTSVHGTSSENG--------AKDDYLTLPNSQGKGNLGNR-FSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . : . . : . .: * : : * * . . : :.* : .. . * ::* . * *:: .. ..:. *: : * .* : * : : : .. : *.. ...:. . . : * : .: .. . : * . . * : * *: . ::* :*.:* *:. :: . : . :: : . . *. . . : ::: * . :: .. . . *: . .:*:: : . *:. : :: :: . .: : : .: . * . . .: :: :* * : : : : : ..: .. : : : : *. * . : * . : : : : . : . * : : * : :. : : .. :.. ::.. .: : : : * *: .::* :: . : : . : : .::.* : . . .:: . : : :: . . : : . * :: : . . .. : * : ::: : : : : : . : : :.::. : : * : :. : .:: : . .. : : .: . * . .: . : : : :: :: : : : ", "identical_positions": 43, "similar_positions": 263, "identity": "3.83%" }, { "cls_id": "homologset.agr.FB:FBgn0003975", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG38-1", "uniprot_id": "D3ZG38_RAT", "id": "D3ZG38-1", "name": "", "aln": "--MSCLDVMY--QVYGPPQPYFTAAYTPYHQKLAYYSKMQEAQECSASPCSSASGS--STFSNQTPASVKEEEG----SPEKERPPEAEYINSRCVLFT-----------------YFQGDISSVVDEHFSRALSQPSSYTPSCSSSKTHRSSGPWRAEGTFPMNQRS-FPASFWNSAYQA----------PVPAPLGSPLAAAHSELPFAT-DPYTP--AALHGH-LHQG-------AAD------------------------------------------------------WHHAHPHHAHPHHPYALGGALGAQASAYPRP-AVHEVYAPHFDPRYGPLIMPAASGRPGRLAPASAPAPGSPPCELAAKGEPAGGAWAAPGGPFVSPAGDVAQSLGLSVDSGKRRRECSLPSAPPALYPTLG----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGW8-1", "uniprot_id": "VGLL2_MOUSE", "id": "Q8BGW8-1", "name": "Transcription cofactor vestigial-like protein 2", "aln": "--MSCLDVMY--QVYGPPQPYFAAAYTPYHQKLAYYSKMQEAQEC-ASPGSSASGS--SSFSNPTPASVKEEEG----SPEKERPPEAEYINSRCVLFT-----------------YFQGDISSVVDEHFSRALSHPSSYTPSCTSSKAHRSSGPWRAEGTFPMSQRS-FPASFWNSAYQA----------PVPAPLGSPLAAAHSELPFAT-DPYSP--ATLHGH-LHQG-------AAD------------------------------------------------------WHHAHPHHAHPHHPYALGGALGAQASAYPRP-AVHEVYAPHFDPRYGPLLMPAATGRPGRLAPASAPAPGSPPCELAAKGEPAGSAWAAPGGPFVSPTGDVAQSLGLSVDSGKRRRECSLPSAPPALYPTLG----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8G2-1", "uniprot_id": "VGLL2_HUMAN", "id": "Q8N8G2-1", "name": "Transcription cofactor vestigial-like protein 2", "aln": "--MSCLDVMY--QVYGPPQPYFAAAYTPYHQKLAYYSKMQEAQECNASPSSSGSGS--SSFSSQTPASIKEEEG----SPEKERPPEAEYINSRCVLFT-----------------YFQGDISSVVDEHFSRALSQPSSYSPSCTSSKAPRSSGPWR-DCSFPMSQRS-FPASFWNSAYQA----------PVPPPLGSPLATAHSELPFAAADPYSP--AALHGH-LHQG-------ATEP-----------------------------------------------------WHHAHPHHAHPHHPYALGGALGAQAAPYPRPAAVHEVYAPHFDPRYGPLLMPAASGRPARLATAPAPAPGSPPCELSGKGEPAGAAWAGPGGPFASPSGDVAQGLGLSVDSARRYSLCGASLLS------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZZ09-1", "uniprot_id": "D3ZZ09_RAT", "id": "D3ZZ09-1", "name": "", "aln": "--MSCAEVMYHPQPYGAPQYLPNPVAAATCPTACYHPAPQPGQQKKLAVYSKMQDS--LEVTLPSKQEEEEEEEDEDEEEEKDQPAEMEYLNSRCVLFT-----------------YFQGDIGSVVDEHFSRALGQANTLHPESAISKSKMGLTPLWRDSSALSSQRSNFPTSFWTSSYQP----------PPAPCLGGVHPDFQVTAPHGTFTTADP--NSWPGHGLHQTGPAPPPTASES-----------------------------------------------------WHYPLASQVSPSYSHMHD-MYMRHHHPHAHMHHRH--HHHHHHPTAGSALDPAYG--HLLMPSVRAARIPAPQCDITKTDLTTATTATSAWAGAFHGTVDIVPSVGFETGLQHQDKSKESTWY-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P85442-1", "uniprot_id": "VGLL3_MOUSE", "id": "P85442-1", "name": "Transcription cofactor vestigial-like protein 3", "aln": "--MSCAEVMYHPQPYGAPQYLPNPVAAATCPTACYHPAPQPGQQKKLAVYSKMQDS--LEVTLPSKQEEEEEEEEDEEEEEKDQPAEMEYLNSRCVLFT-----------------YFQGDIGSVVDEHFSRALGQANTLHPESAISKSKMGLTPLWRDSSALSSQRSNFPTSFWTSSYQP----------PPAPCLGGVHPDFQVTAPHGTFTTADP--NSWPGHGLHQTGPAPPPTASES-----------------------------------------------------WHYPLASQVSPSYSHMHD-MYLRHHHPHAHVHHR---HHHHHHPTAGSALDPAYG--HLLMPSVRAARIPAPQCDITKTDLTTVTTATSAWAGAFHGTVDIVPSVGFDTGLQHQDKSKESTWY-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MV65-1", "uniprot_id": "VGLL3_HUMAN", "id": "A8MV65-1", "name": "Transcription cofactor vestigial-like protein 3", "aln": "--MSCAEVMYHPQPYGASQYLPNPMAATTCPTAYYQPAPQPGQQKKLAVFSKMQDS--LEVTLPSKQEEEDEEE---EEEEKDQPAEMEYLNSRCVLFT-----------------YFQGDIGSVVDEHFSRALGQAITLHPESAISKSKMGLTPLWRDSSALSSQRNSFPTSFWTSSYQP----------PPAPCLGGVHPDFQVTGPPGTFSAADP--SPWPGHNLHQTGPAPPPAVSES-----------------------------------------------------WPYPLTSQVSPSYSHMHD-VYMRHHHPHAHMHHRHRHHHHHHHPPAGSALDPSYG--PLLMPSVHAARIPAPQCDITKTEPTTVTSATSAWAGAFHGTVDIVPSVGFDTGLQHQDKSKESPWY-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q26366-1", "uniprot_id": "VG_DROME", "id": "Q26366-1", "name": "Protein vestigial", "aln": "MAVSCPEVMYG--AYYPYLYGRAGTSRSFYQYERFNQDLYSSSGVNLAASSSASGSSHSPCSPILPPSVSANAAAAVAAAAHNSAAAAVAVAANQASSSGGIGGGGLGGLGGLGGGPASGLLGSNVVPGSSSVGSVGLGMSPVLSGAAGHSLHSSHRTHAHSLAHAHTHPHSHTHTHTHQTKEEDLIVPRSEAEARLVGSQQHQHHNESSCSSGPDSPRHAHSHSHPLHGGGGATGGPSSAGGTGSGGGDGGGTGAIPKNLPALETPMGSGGGGLAGSGQGQAQYLSASCVVFTNYSGDTASQVDEHFSRALNYNNKDSKESSSPMSNRNFPPSFWNSNYVHPIPAPTHHQVSDLYGTATDTGYATDPWVPHAAHYGSYAHAAHAHAAHAHAYHHNMAQYGSLLRLPQQYASHGSRLHHDQQTAHALEYSSYPTMAGLEAQVAQVQESSKDLYWF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** :*** * . . : .. : *. ..* : . . : :: .. : :. . : .* :.* * * . . * : : . . :. : . ::*. . * . : . : . * .* ** : : . :. .. . . . . *: .. . : : : . . . * :: ", "identical_positions": 21, "similar_positions": 70, "identity": "4.62%" }, { "cls_id": "homologset.agr.FB:FBgn0003977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKC9-1", "uniprot_id": "D3ZKC9_RAT", "id": "D3ZKC9-1", "name": "", "aln": "MPRGRLMVLRVLIWHNFLLFARTHGPSQASWRLRSGERRDLDHRKHRSPLPSFFLPFWAFRRRPPPRWRRRGLRLKVVRCDGIGRGLRRRRPIYRKCCSFPLAGASAWEVGELPRKSSPGPPPAANMAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNS-KVNTDGLVLRGWYNCLTLAIYGSVDRVLSHDRDSPPPPPPPPPPPQPQPT-----------------------------------------LKRSLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLP-VSGDKEED------VPHR-EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEDDEDDVDVDEEEDEDEDDCHTVDSIPDDDEEDEEEEGEEDEEG--EGDDGYEQISSDEDGIADLERETFKYPNFDVEYT--PEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEINRMKDQGPDKENSGAIEASLKLTELLDLYHE----DRGAKWVTALEEVP------SLIIKGLSYLQLKNTKQDS--LGQLVDWTMQALNLQVAFRQP-IALNVRQLKAGTKLVTSLAECG--APGVTELLQAGVISVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQSE----KSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLG----------DHIAEKTSSVPNPSEPDHDTD--AVLERANPDYENEVEASMDMD-LLESSNISEGEIEKLINLLEEVFHLMETAPHTMIQPPVKSFPTIARITGPPERDDPYPVLFRYLH---SHHFLELVTLLLSIPITSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQD----------------EEEGLQSDG-VDDAFALWLQDSTQTLQCVTELFSHFQ--------RCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYS-----KEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADE-----NNAKLQELGKWLEPLKNL-RFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQ----KDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQT--TQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDEK--------YAEIFQDLLALVRSPGDS-VIRQQCVEYVTSILQSLCDQDIALILPSPSEGPGSELEQLSNSLPSKELMAAICDCLLATLANSESTYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVST-------FSKDTGELTSASLDFMRQILNSDAMGCCGDDSGLMEVESAHPPRTMSIN-----AAELKQLLQSKEESPESLFLELEKLVLEHSKEDDSLESLLDNVIGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNR---TAYVLADVMDDQLKSMWFTPFQAEEIDTD----LDLVKVDLIELSEKCCS-DFDLHSELERSFLSEPSSPGRAKTTKGFKLGKHKHETFITS---SGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVS-QKISSRGGFSGNRGGRGAFHSQNRFFTPPASK-----GNYSRREGTRGSSWSAQN---TPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWAST---------NSGSGGSRGKSKQPKTF--HHHH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AIV2-1", "uniprot_id": "VIR_MOUSE", "id": "A2AIV2-1", "name": "Protein virilizer homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------MAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNS-KVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPT-----------------------------------------LKRNLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLP-VSGDKEED------VPHR-EDYFEPISPDRNSVPQEGQYSDEGEVEEEPQEEGEDDEDDVDVEEEEDEDEDDCHTVDSIPDDEEEDEEEEGEEDEEG--EGDDGYEQISSDEDGIADLERETFKYPNFDVEYT--PEDLASVPPMTYDPYDRELAPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAVEASVKLTELLDLYQE----DRGAKWVTALEEIP------SLIIKGLSYLQLKNTEQDS--LGQLVDWTMQALNLQVAFRQP-IALNVRQLKAGTKLVTSLAECG--APGVTELLQAGVINVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQNE----KSGYQRLLELILLDQTVRVVTAGSAILQKCHFYEILSEIKRLG----------DHIAEKTSAVPNHSEPDQDTD--AVLERANPDYENEVEASMDMD-LLESSIISEGEIEKLTNLLEEVFHVMETAPHTMTQPPVKSFPTIARITGPPERDDPYPVLFRYLH---SHHFLELVTLLLSIPITSAHQGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQD----------------EEEGLQSDG-ADDAFALWLQDSTQTLQCITELFSHFQ--------RCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYS-----KEALGDSKSKKSVAYNYACVLTLVVAQSSSGVQMLEQHAASLLKLCKADE-----NNAKLQELGKWLEPLKNL-RFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQ----KDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQT--TQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDER--------YAEIFQDLLALVRSPGDS-VTRQQCVEYVTSILQSLCDQDIALILPSPSEGPASELEQLSNSLPSKELMTAICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVST-------FSKDTGELASASLDFMRQILNADAMGCCGDDSGLMEVEGAHPPRTMSLN-----AAELKQLLQSKEESPESLFLELEKLVLEHSKDDDSLESLLDNVIGLKQMLESSGEPLPLSDQDVEPVLSAPESLQNLFNNR---TAYVLADVMDDQLKSMWFTPFQAEEIDTD----LDLVKVDLIELSEKCCS-DFDLHSELERSFLSEPSSPGRSKTTKGFKLGKHKHETFITS---SGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVS-QKISSRGGFSGNRGGRGAFHSQNRFFTPPASK-----GNYSRREGTRGSSWSAQN---TPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWAST---------NSGSGGSRGKFVSGGSG--RGRHVRSFTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69YN4-1", "uniprot_id": "VIR_HUMAN", "id": "Q69YN4-1", "name": "Protein virilizer homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNS-KVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPS-----------------------------------------LKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLP-VSGDKEED------APHR-EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEG--EGDDGYEQISSDEDGIADLERETFKYPNFDVEYT--AEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAIEASVKLTELLDLYRE----DRGAKWVTALEEIP------SLIIKGLSYLQLKNTKQDS--LGQLVDWTMQALNLQVALRQP-IALNVRQLKAGTKLVSSLAECG--AQGVTGLLQAGVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNE----KSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLG----------DHLAEKTSSLPNHSEPDHDTD--AGLERTNPEYENEVEASMDMD-LLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARITGPPERDDPYPVLFRYLH---SHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHFYDQD----------------EEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQ--------RCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYS-----KEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADE-----NNAKLQELGKWLEPLKNL-RFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQ----KDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQT--TQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDER--------YAEIFQDLLALVRSPGDS-VIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNKELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVST-------FSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSIN-----AAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNR---TAYVLADVMDDQLKSMWFTPFQAEEIDTD----LDLVKVDLIELSEKCCS-DFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITS---SGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVS-QKISSRGGFSGNRGGRGAFHSQNRFFTPPASK-----GNYSRREGTRGSSWSAQN---TPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASA---------NSGSGGSRGKFVSGGSG--RGRHVRSFTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4B7-1", "uniprot_id": "A0A8M2B4B7_DANRE", "id": "A0A8M2B4B7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------MAGDSAMELLFLDTFKHQNAELT-NVDVVRFPYGVLITEVRVIPPGIKAHSNLPDSRAFGETAPHAFQLDLFFNNVSKPNSPVFDRLGSLEYDENKSIIFRPNG-KINTDGLVLRGWYTCLTLAVYGTAERPHSHERDSPPPPPPPPP--QQQQI-----------------------------------------GSKRLIKLEWENEDQFNGSPPRPQPRGPRTPPGPPPPDDDDEEAMPAPGQCPVKVEN------TEHPGDDYLEPVSPERGSLPADETYSD----AEQEDDEGPADEEEDDVQSEGTEGDED----------DEEDEVGDDVTDEDG--EGDDGYEQISSDEE---DLESGAFKLPAFDLDYT--PEDLASLPTVQYDPYERELRPLQHFTPPHITRYEAELKRLKTVDIEDSSSSWAESAAKLSELLEAWGEAQGAERGAGWVTALEEVP------AFLVKGMSFLSIKDPDGQSEKLKQLVDWSCEALSLDVALAQP-IALNLRQLKAGTKLVSALADCG--AQAVQDLLEKGIVGRLLGLLFAEHVSSTLKLNVLRSLDSIISEPQGIEAMLRDRHHHDDDGTSGYQRLLDLFLLDQTVRVATAGAAILHKGHLYEVLTDLQKTASVWAERHPTVGEVAEREGSESEAGERDRESTEREGEERERETQEAERESPMDIDTLLESASLSEADLERLQGLLEELLHLLETAPHCMVQPPGKAFPTNVRITGPPERDDPYPTLYRYMH---ACHLLESLGVVLSYPATCAHIGVLQAVRELMRFLSQSQQGLLFLLSQHETINLLLRLLTPLTHLTPPSHLAPLTPLSEVEGEEAAAGGEGLMDDGFWVWLMQTLHALQGIAELN-------------GAELEDGDNPDVLATLHSLYLISFSSTGRNAVAHTFSLDNNLSCLINLIEFHA-----KDGQGDGKARKSVTYNYACMLVLLVIQTSSDLRMMEHYAAPLLLVCKADE-----NNAKLQELSKWLEPLEKL-HFDISGIPMLIDYIKQNLENLMTADGVGLVTALRVLCHIACPPATVPGQQ----KDLKWNQAIIALFSAEGMDTFIKVLQKLTSLLLLPWRLHGPMGPTAQRLMMLSVASCSLRLIRAMLTELLCGGTCEFRDVRVPSVCVTLHKILCSTPSTGRLDAEELRIQGDVTEILLTFTHAVSEQETGSEETVAGNSWSLMLKEVLNSILAAPENIYSSLSLLSELLPLPLPMQT--TQALSVQDIGVAMNTRKLWSVHLHAQARVLQEVLRCACVSSCPPLFSMLRRVCVQLCDLAAPTATLVMRTLLEQLQEEMQQEAAG------SRLIRVLALLDSLASQRACKVAMLALLSGSARSDTRSEGKVEDKLSDILPSLLAMLVLPADVGLSAQQNAELMASILQSLCDQDVSLVVSGSGEASVSEAELLANALPTKEMMTSICEGMLDVLGNTHSSYTLQLTCLRTMMFLTEHDYGLYHLKSSLKKHTTAISSLIRREITS-------FNKEFAELLSALFDFLRQILNSEAMFLRSAFYRHHHADEDMDSRSLALS-----VSDMKQLLQWKEDSGEHLLCELEKHITKLCKEDESLEALLENVVGLRQIIESSGDAQTNAEPETEPSLPAPEPLQTQFNHR---TVYVLSDVLDEQLKALWFSPFQPDEMETE----VDMVKVDLVALAQQCCT-ELDLKAELERSFLSEPSSPGHSKPSKGFRLGKHKHETFITSRYTSGRSDYVEPAKRAHIMAAPRGRGRGSFGQLSRPHDIFRQRKQNTSRPPSMHVDDFLAAEFKDVGPPTGLTLPKRPPKGGGAKPPTRGMFTGGTRGRG-FQSHTRFFTPPAPKSVLLAGNYPRREGGRGSTWSTPVTAVTHRGTYSEPRGGQSNFTR-PLPSRQPPTG-AYRLAPRDRATRGRG-TGLSWLSAGVSVGGGGGVSGGGRGQGKFSSGGSGGGRGRHVRSFTR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1R5-1", "uniprot_id": "VIR_DROME", "id": "Q9W1R5-1", "name": "Protein virilizer", "aln": "-----------------------------------------------------------------------------------------------------------------------------MADVDDGSELLFFDTFSH-EEVTDINLDLVQFPKPVFITQVRIIPLGARVQADFPGGVRLGATNPSKFDLEFFVNDLGMPAASAFENLGLLRYNQNDCIHLDCSQEKIVTDGLVLRGWYSTITLAIYGIFTNSVTEPIASPTLPCEPVGPEIANLSGEVLLQEDVLKDEWQEPMQAELLTAHKGNVSDYDPEDMEYGMSRDHYHQHAEEQEQREMRRLRRSTHSTDHSPPPPRRSHTHSESNDREYIRCSRDKGSRDWSRSPEYSSHRSRRKRSERSRSVVDEHKWPRTPPASIDSPTRPRSPDTMDYEDEDSRSHYKMQSSHYRHSSESLHRGERDRDDEDRSCTPQEQFEPILSDDEIIGDDEEDDAVDAAAIAEYERELEAAAAAAPPAIDAFEPWQKPLLVFEGDMAAHFCKELETLKLLFKKLVLQTRCENVNAFSEEHGASVD-----EREQFVYLGEQLNNQLGYLAQHYKRRNFVLQQFFGNDELHLRQAANVLQIALSFQAACMQPQPAFKIRHIKLGARMAELLGSSEELFQHLLKEHKFDIFEAVFRLYHEPYMALSIKLQLLKAVYALLDTRMGIEHFMGAKNNG-------YQMIVEAIKTAKLTRTKYALQAIIKKLHLWEGLESVQIWCR----------RLFVDRIIIPGNRDQMEDTVITCQQIEFAFEMLMDALFSSQLSYLQPRRFLPVSKKFEVVTDPTAQRSFGNALQSYLGQNSLAESLLVMLANCKELPATTYLSMLDLMHTLLRSHVGIDYFVDDAFPVTQTIVAILLGLDEVPRNPEEKEEKAEKSDAEDKAMEVENEAVEAGGEKPTPPTADEEGKPVAAPISVPAPAAAPQVRPRPILRPVLPRLARLGIEMSYKVQTRYHLDAIAYAAAAPEYDAVKLATHMHAIYSQTCDPAGRQHTVEVLGLNNNLKIFMDLIKKEQRLQTQRQLSSPGTKYKSPVLSYAVDMVDACVRYCEQLDYLIEHGGVILELAKNHETFEPSVSAVLQEMYVYMKPLEAINVFVYDDIMPLVEVIGRSLDYLTTFPGD-LIMAMRILRYLSISKPLAGQKAPPVTEELKHRFVALQLYAADGVQLCIQIMERLCAYFEQPG-AHAPALMTIQGVHCCQIMLPTLQILRELLSYAILCRDGTYKDLTAIDHLVKVYYLLYYFPTRCQAGPEVEQCKMEVVQTLLAYTQPNEQD----EESLHKSLWTLMIREVLKNVDG-PAHFIPGLKLLAELLPLPLPMPQPLCDQLQQQHKQRLITERKLWSAHLHPQSGQIAKLVEALAPSSFPQLSELLQRVCMQLSDLAPNMTLLIAKTITELLCNEYQTSNCIP----TTNLERLLRFSTRLCAFAPLKSSMLSILSG--------------KFWELFQSLLALN----EFNDVVSNCQEAVHRILDSFLDSGISLIS---HKSTASPALNLAAALPPKELIPRIIDAVFSNLTSVEVTHGISILAVRNLVILTEHDFTFYHLAQLLKQKITEFQAWMERVILHNETVEYNANIESLILLLRSLTQIEPPPAMSAMPHRTLKLGATELAQLVEFQDIELAKPPVLSRILTVMEKHKAVANEAALSDLKQLILLQASKQEILAGTSTETPPEAEGEANPSASSCSASLTVEPYLPQAEGIVTQYEARPIFTRFCATAENAQLTARYWLDPLPIELIEDMNEPIYERIACDLTDLANVCLNPDLNVAGDSKRVMNLSGSPQSNREMTPTAPCFRTRRVEVEPATGRPEKKMFVSSVRGRGFARPPPSRG-----------DLFRSRPPNTSRPPSLHVDDFLALETCGAQPTGPTGYNKIPSMLR---GSRVGRNRGSRISAAAAFRQKKMMRIGSPS-----------------SWAESP------GSYRSASDSHFSSSD------SHYSSPHYSGRPRGRGLRSRPSYLR-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. ****:***.* . ::*:*:** * *.:**:** * :.::.:*.. * * * *:*::*.*::. * :..*:.** *.*::* .* : . *: **********. :***:** . :. **. * * : .: : . *:::* : * ..:.. .* ** .. ..:. : :. . .. . .:*. : . . . : * :.* ... . :. .. . **: :: :* * **:: * * . :* * *: .. *.:: ** * : : *:. :* . . * ::* : . :* *:: : * .:: : :. * * .: **.::.* ** *:::*::* *:::. *... : : .:. :: * . ::: ::**: :::: :::. *:* :: : ** ::: : : .*. * **::* *::* * .:: .: . : .:: . : . ::. * :. .. .: . :: : * . . .* : :* *. : : * * : .:* . :: : :.:: :: :: :: . : . . . . : . : : : : * .: :* :* : ...**. . ..:.*::**. :: *:: :: . .. ** . .** : : .. : : .:.. :* :.* .* .* ***: :::**: : * . * *:: : :.:: * * * * *:*:* :: . . . : ::** . . : *::*:*:: *:::::* : : * * * : : .: :* ::: :*: : ::*: . . *.:: :* * : ..: : : :: : **::*: .:. **:: . *:**::***..: * : ..* **:********* : :. :. :. ***** *** *: : :::.. . :: : :*:*:*:**.***. : *: :*: : : :: * :. *:* : *.: . * ::* ::.* ::: .***: : .: * : **:*: *..::*: :.. * *: :** **::. * : :: * . . :: : .:*.:::*:***: ::** . *::: : : : :.* : . : * : :. .:: . : : : :. : : * : * : :*:: : ...:: * . .. : ... . :. .** *. .* : . :: * * : : : *: *: : :: : : ** *:: * . :::: .: :* : . *. .. : : : :: . .: . :. ::...: . .* .** *:**.* *******:*****:* * . * * * . * *. . . :.::: :.. :*: *.* .. ..: . . :. * **.*. *.* ", "identical_positions": 300, "similar_positions": 593, "identity": "14.15%" }, { "cls_id": "homologset.agr.FB:FBgn0003978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QR85-1", "uniprot_id": "MEP50_RAT", "id": "Q4QR85-1", "name": "Methylosome protein WDR77", "aln": "-------------MRKESPPPLVPPAAREWN---------LPPNAPACMERQLEAARYRSDGSLLLGASSLSGRCWAGSLWFFK-DPSAAPNEGFCSAGVQTEAGVADLTWVGDKGILVASDSGAVELWELDENETLIVSKFCKY------EHDDIVSTVTVLSSG-TQAVSGSKDFCIKIWDLAQQMSLNSYR---AHAGQVTCVAASPHRETVFLSCSEDSRILLWDTRCPKPASQMGCNASGYLP--TSLAWHP----QQSEIFVFGDENGSVSLVDTKNASCTLSS--AVHSQCVTRLVFSPHSVPFLASLSEDCSLAVLDSSFSEVFRSRAHRDFVRDATWSPLNHSLLTTVGWDHQVIHHVVPLEPLPAPGPDSVVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J09-1", "uniprot_id": "MEP50_MOUSE", "id": "Q99J09-1", "name": "Methylosome protein WDR77", "aln": "-------------MRKDTPPPLVPPAAREWN---------LPPNAPACMERQLEAARYRSDGSLLLGVSSLSGRCWVGSLWFFK-DPSAAPNEGFCSAGVQTEAGVADLTWVGDKGILVASDSGAVELWELDENETLIVSKFCKY------EHDDIVSTVTVLSSG-TQAVSGSKDCCIKIWDLAQQVSLNSYR---AHAGQVTCVAASPHKDSVFLSCSEDSRILLWDTRCPKPASQMACNASGYLP--TALAWHP----QQSEVFVFGDENGSVSLVDTKNASCTLSS--AVHSQGVTRLVFSPHSVPLLTSLSEDCSLAVLDSSLSEVFRSRAHRDFVRDATWSPLNHSLLTTVGWDHQVIHHVVPLEPLPNPGPDSVVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQA1-1", "uniprot_id": "MEP50_HUMAN", "id": "Q9BQA1-1", "name": "Methylosome protein WDR77", "aln": "-------------MRKETPPPLVPPAAREWN---------LPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWLFK-DPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFCKY------EHDDIVSTVSVLSSG-TQAVSGSKDICIKVWDLAQQVVLSSYR---AHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLP--TSLAWHP----QQSEVFVFGDENGTVSLVDTKSTSCVLSS--AVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIP8-1", "uniprot_id": "VLS_DROME", "id": "Q9VIP8-1", "name": "Protein valois", "aln": "MFPQRSSELYRTPVTHQPPPALELAGNLEYPNLNIADLNARLENLSPRLHDCWDSIAINDHNHLALATNRREGRQWWGMLFGYGRDQMHHMSVDSANFKLQAEHTVNIVRYAEDDFLLVALGDTRLQAWSTYSKVRDSQSPYCLFLVGESSAHPTPISQLSVFKADPRTAVSGSADSTLNVWDLSGADMVSTYRSRSSHTDKLTGLATPAASVDKFVTCDRGGCARLWDVRAAAPSSTCLYADASHVLSFTSAAWAAASELQGDNHIYLGDYDGKVHTLDIRVPRKLAETREYFDKGHVAQLLINGPHLAAMSNLPASVKVANVQAGHEFIYTHQDTHSRLTDAVWT--DDSTLITIGHGRKMVTHAIK--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::.**.* .. *: * .. :. :: .... * *... .** * * *: : * . . .. :*:* * : :. : :*** .. :: *. .: * :* : * :* ::*:.:. ***** * :::***: :.:** :*: ::* :*:.. *::*.... ***.*.. *:* ..:: *: ** . * .: : :** :*.* :* : . .: ... *: *::. :. ::.*. . .:* :::. . :: : :. : **.*: :.* * *:* .:::: *.: ", "identical_positions": 68, "similar_positions": 132, "identity": "17.75%" }, { "cls_id": "homologset.agr.FB:FBgn0003984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43322-1", "uniprot_id": "NRG1_RAT", "id": "P43322-1", "name": "Pro-neuregulin-1, membrane-bound isoform", "aln": "------------------------------------------------------------------------------------------------------------MSERKEGRGKGKGKKKDRGSRGKPGPAEGDPSPALPPRLKEMKSQESA------AGSKLVLRCETSSEYSSLRFKWFKNGNELNR-------------------KNKPENIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEFITG------------------------------------------------------MPASTETAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLIKCAEKEKTFCVNGGECFTVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYMTSRRKRQETEKPLERKLDHSLVKESKAEELYQKRVLTITGICIALLVVGIMCVVAYCKT----KKQRQKLHDRLRQSLRSERSNLVNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREVETS--FSTSHYTSTAHHSTTVTQTPSH-----SWSNGHTESVISESNSVIMMSSVENSRHSSPAGGPR--GRLHGLGGPRD-NSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSVAVS----PFVEEERPLLLVTPPR--------------------LREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYESVQ--------EPVKKVTNSRRAKR-TKPNGHIANRLEMDSNTSSVSS------NSESETEDER-----VGEDTPFLGIQNPLAASLEVAPAFRLAESRTNPAGRFS----TQEELQARLSSVIANQDPIAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DR98-1", "uniprot_id": "NRG1_MOUSE", "id": "Q6DR98-1", "name": "Pro-neuregulin-1, membrane-bound isoform", "aln": "------------------------------------------------------------------------------------------------------------MSERKEGRGKGKGKKKDRGSRGKPAPAEGDPSPALPPRLKEMKSQESA------AGSKLVLRCETSSEYSSLRFKWFKNGNELNR-------------------RNKPQNVKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNDLTTG------------------------------------------------------MSASTERPYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLIKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLG------------------IEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKT----KKQRQKLHDRLRQSLRSERNNMVNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREVETS--FSTSHYTSTAHHSTTVTQTPSH-----SWSNGHTESIISESHSVIMMSSVENSRHSSPAGGPR--GRLHGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSVAVS----PFVEEERPLLLVTPPR--------------------LREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYEPIQ--------EPIKKVTNSRRAKR-TKPNGHIANRLEMDSNPSSVSS------NSESETEDER-----VGEDTPFLGIQNPLAASLEVAPAFRLAESRTNPAGRFS----TQEELQARLSSVIANQDPIAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02297-1", "uniprot_id": "NRG1_HUMAN", "id": "Q02297-1", "name": "Pro-neuregulin-1, membrane-bound isoform", "aln": "------------------------------------------------------------------------------------------------------------MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESA------AGSKLVLRCETSSEYSSLRFKWFKNGNELNR-------------------KNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG------------------------------------------------------MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEK-----------------------AEELYQKRVLTITGICIALLVVGIMCVVAYCKT----KKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETS--FSTSHYTSTAHHSTTVTQTPSH-----SWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPR--GRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVS----PFMEEERPLLLVTPPR--------------------LREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQ--------EPVKKLANSRRAKR-TKPNGHIANRLEVDSNTSSQSS------NSESETEDER-----VGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFS----TQEEIQARLSSVIANQDPIAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35569-1", "uniprot_id": "NRG2_RAT", "id": "O35569-1", "name": "Pro-neuregulin-2, membrane-bound isoform", "aln": "MRQVCCSALPPP-LEKARCSSYSYSDSSSSSSSNNSSSSTSSRSSSRSSSRSSRGSTTTTSSSENSGSNSGSIFRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGSSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVG------SCAPLERNQRYIFFLEPTEQPLVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGE-VGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPNGFFGQRCLEKLPLRLYMPDP------------KQKHLGFELKEAEELYQKRVLTITGICVALLVVGIVCVVAYCKT----KKQRRQMHHHLRQNMCPAHQNRS-LANGPSHPRLDPEEIQMA-DYISKNVPATDHVIRREAETT--FSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAP----ISYRLAEQQPLLRHPAPPGPGPG------PGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRR-SRLNGLAAQRARAARDSLSLSSGSGCGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDS-HSTRASSRHSRGPPTRAKQDSGPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56974-1", "uniprot_id": "NRG2_MOUSE", "id": "P56974-1", "name": "Pro-neuregulin-2, membrane-bound isoform", "aln": "-------------------------------------------------------------------------------------------------------------MRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVG------SCAPLERNQRYIFFLEPTEQPLVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGE-VGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVRVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPVGYTGDRCQQ-----FAMVN-------------FSKHLGFELKEAEELYQKRVLTITGICVALLVVGIVCVVAYCKT----KKQRRQMHHHLRQNMCPAHQNRS-LANGPSHPRLDPEEIQMA-DYISKNVPATDHVIRREAETT--FSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAP----ISYRLAEQQPLLRHPAPPGPGPGSG----PGADMQRSYDSYYYPAAGPGPRRSACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRR-SRLNGLAAQRARAARDSLSLSSGSGCGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDS-HSTRASSRHSRGPPTRAKQDSGPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14511-1", "uniprot_id": "NRG2_HUMAN", "id": "O14511-1", "name": "Pro-neuregulin-2, membrane-bound isoform", "aln": "MRQVCCSALPPPPLEKGRCSSYS---DSSSSSSERSSSSSSSSSESGSSSRSS--------------SNNSSISRPAAPPEPRPQQQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVG------SCVPLERNQRYIFFLEPTEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQ-VGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLYVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPNGFFGQRCLEKLPLRLYMPD--------------------PKQKAEELYQKRVLTITGICVALLVVGIVCVVAYCKT----KKQRKQMHNHLRQNMCPAHQNRS-LANGPSHPRLDPEEIQMA-DYISKNVPATDHVIRRETETT--FSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYNLEERRRATAPPYHDSVDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAP----ISYRLAEQQPLLRHPAPPGPGPGPGPGPGPGADMQRSYDSYYYPAAGPGPRRGTCALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRARGASRRTSAGPRRWRR-SRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGALAAESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDS-HSTRASSRHSRGPPPRAKQDSAPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAC4-1", "uniprot_id": "A0AB32TAC4_DANRE", "id": "A0AB32TAC4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------MRRLDSVHLSMLLIGVSFACYSPSLNSLQDQAYRSAVVIEGKVQSAP------QNVSAEPYSVN----VKVLDVWPRNSGGLEREQLVTVGEFGSEAPCAKVKKNHKYIFFMDPTDEPLVFKASFAPLDTSGKNLKKDVGRILCEDCAAFPSLRRMKNPVLADEGSRLIVKCEATG-SPAPEYKWYKDGAELKRSKEIKIR--NNKKNSKVQIGSAKLEDSGNYTCVAENILGKANGTSTVHVQSITTTVSPGSGHARRCNDTEKTYCVNGGDCYYIHGINQLS---CKCPNDYTGDRCQTS-----VMAS-------------FYQSLGIEFMEAEELYQKRVLTITGICVALLVVGIVCVVAYCKTNLPPRKQRKKMHNHLRQNIYVDHPNRN-LANGPNHPGPGPEEIPMV-DYISKNVPATERVIRHGAEAP--FPGSRQSSRSHNSSTRAHSSTHRHEGRTWSLERTDSVLSDCPSGLMSSSVGTSKCNSPACMEARARRAAHCGFTEPHRPALQ-YGDSFDSLGDSPHSDRYVSALTTPARLSPVDFHYSLPPQVPTFQITSPNASHAMSLPPAA----HAPYPPEEDQPLLRRYQVP-------------LHEARGHEPYRQQQRG-------SYLRDSTGSLPSSPYRLAQEDEYESTQEYLSSM--------EQPKRSS--RRWRR-SRLNGHVAPRGYQPSRDLGSRS-----CLSDSDSEEEE------GESTPFLSMQNMNAAEP--SALYRPVPDTRTSHAQSGRHGSRANTQT-RLTHSRSKPDNAPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B3W8-1", "uniprot_id": "A0A8M2B3W8_DANRE", "id": "A0A8M2B3W8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------MRRLDPVHFSMLVIGVSFACYAPSLDSLQDQAYRSAVVIEGKVSSLP------ENVSVEPYSVN----VTVLYVWPVNSGGLKREQLVTVGEFGSEAPCVAVEKHHTYIFFMDPTEEPLVFKASFAPLDSTEKTLKKDVESVLCKDCASAPKVKPMDSQWLQ-EGKKLTLKCEAVG-NPSPSFNWYKDGSQLRQKKTVKIK--TNKKNSKLHISKVRLEDSGNYTCVVENSLGRENATSFVSVQSITTTLSPGSSHARKCNETEKTYCINGGDCYFIHGINQLS---CKCPNDYTGERCQTS-----VMAG-------------FYKHLGIEIMEAEELYQKRVLTITGICVALLVVGIVCVVAYCKT----KKQRKKMHNHLHQNMCAEHPNRM-LANGPNHPGPGPEEIPMV-DYISKNVPATERVVRHGTETSGNFSGSRMSSRSHHTSTASHTSSHRHEERTWSMERTDSIHSDCQSGALSSSVGTSKCSSPACMEARARRAAYCGYPDATQCSLQ-YGDSYDSLRDSPHSDRYVSALTTPARLSPVDFHSSLPPQVPTFQITTPNASHALSLPPAASAIAMAAYSPDDDQPLLYR--------------------------YRRSRRP-------YYAAESTGSLPSSPYRFVDDEDYETTQEYMSSR--------EQPKKSSGSRRWRRRSRINGHTPG-----PRNYSSQS-----CLSDSEWEDEEVGDLGHGESTPFLSMQNMNATEP--ATIYRPN-DTRT-FSNTGRSGSRPNVQANKLTQSRFRPDNAPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94918-1", "uniprot_id": "VEIN_DROME", "id": "Q94918-1", "name": "Protein vein", "aln": "-----------------------------------------------------------------------------------------------------------MYAQHLRKWSLKTKKQLMPLILLIISYMLLLNTCVLSSSATTQQQQQQQ------QQQQHLPRLWEGSAEESSYYIPLSSDNGSGS----------------------------SESSAESGSSSSRSSSNNIDNNILSRLLSLNSNSLSSRSNVKLKPATVFD--------------------------------------------------AGSSTPAQQEQHVAAVPEQQQQQQQQQQSMQKVPNTLINSQIYNLLYNGMPSEAASSKMRRHIQPSQLPHQPESRAQLPSNYSSRPAVRS-----------------------------YLIESYEMPESMLEDRSPEQAARSRRDGSNTNGSRQQ------QRTGHRQQLQQDKRDHRRQRQ-------DQQKEQRQQQQQRQHKSGNKHQQQQQQRRKHQRKHQRYNRYCSARDPAQLAFAAPTVFQGVFKSMSADRRVNFSATMKVEKVYKQQHDLQLPTLVRLQFALSNSSGECDIYRERLMPRGMLRSGNDLQQASD----ISYMMFVQQTNPGNFTILGQPMRVTHLVVEAVETAVSEN-----------YTQNAEVTKIFSKPS---------------------------KAIIKHGKKLRIVCEVSGQPPPKVTWFKDEKSINRKRNIYQFK-------HHKRRSELIVRSFNSSSDAGRYECRAKNKASKAIAKRRIMIKASPVHFPTDRSASG---IPCNFDYCFHNGTCRMIPDINEVYCRCPTEYFGNRCEN---KWPDSRYFVAIYGQIHTLNNDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .. : . . .. . . :. : : . : : . :: .: . . . .: .. : :: . : : : . .: : . . : *: :. : : * . . . : ** :.:*:*. : : . .: :: * * :: .: : : : : .. . : * : .. : : .. : : . . . : :. ::.. :* : : .* :* . . : . : . . : : . *.. : ::.. : .:: : * . : . . : . . : . . . . ", "identical_positions": 14, "similar_positions": 135, "identity": "1.54%" }, { "cls_id": "homologset.agr.FB:FBgn0003996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3B3I6-1", "uniprot_id": "A0A8M3B3I6_DANRE", "id": "A0A8M3B3I6-1", "name": "", "aln": "-----------------------MPDNAVFEHDQISEETGRNGQNGSKIIIMEPMKKQHG-------ATVSFHSIRYR-------------VEQKTGPVCRR---TTVQKEILLDLNGIMRP-GLNAILGPTGSGKSSFLDVLAGRKDP---AGLSGEVLVNG-ALQPANFKCLSGYVVQDDIVMGTLTVRENLSFSAALRLSSHVSPREKEARVNHLISELGLNKVADSKVGTQ-IIRGISGGERKRTSIGMELIIDPSVLFLDEPTTGLDASTAHSVLLLLKRMAGQGRTIIMSIHQPRFSIYRLFDSLTLLANGKQVYHGPAQDALDYFSNIGYACEAHNNPADFFLDVINGSSVTKIQNNGDAECDVSAVSRQSVEDQLMEKYRSCSFARAVRAELDHIIQTKDSSSSSVAAECHSITYSSSFCQQLRWVLWRTFWNLMLNPQTSVAQLAVTTLMAAIVGAIFYGVKDDQSGIQNRFGVLFFITTNQCFS-TLSAAELFITERKLFIHEYTSGYYRVSVFFLSKILSDIITQRTIPSVLFSCVVYFMIGLKPTASAFFIFMLTVILVSCTAAAMAMAISADQSVVAVANILMTVSFIFMMIFSGLLVNLKSIMDWLSWLKYLSIPRYGLEALEINEFVGLSFCGNVSESLASPAAHVLMCTGEQHLTFQGIDYSSWGLWQNHVALTVMTLIFLIIAYIKLRFISKFS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10090-1", "uniprot_id": "WHITE_DROME", "id": "P10090-1", "name": "Protein white", "aln": "MGQEDQELLIRGGSKHPSAEHLNNGDSGAASQSCINQGFGQAKNYGTLLPPSPPEDSGSGSGQLAENLTYAWHNMDIFGAVNQPGSGWRQLVNRTRGLFCNERHIPAPRKHLLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEMQARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTIIGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGKTVILTIHQPSSELFELFDKILLMAEGRVAFLGTPSEAVDFFSYVGAQCPTNYNPADFYVQVLAVVPGREIESR----------------DRIAKICDNFAISKVAR-DMEQLLATKN-LEKPLEQPENGYTYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIFLGQQLTQVGVMNINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLTVP-LVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPVIIPFLLFGGFFLNSGSVPVYLKWLSYLSWFRYANEGLLINQWA------DVEPGEISCTSSNTTCPSSGKVILETLNFSAADLPLDYVGLAILIVSFRVLAYLALRLRARRKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 193, "similar_positions": 269, "identity": "27.11%" }, { "cls_id": "homologset.agr.FB:FBgn0004003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52555-1", "uniprot_id": "ERP29_RAT", "id": "P52555-1", "name": "Endoplasmic reticulum resident protein 29", "aln": "--MAAAVPGAVSLSPLLSVLLGLLLLSAPHGASGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENS-ASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFR-DGDFENPVPYSGAVKVGAIQRWLKG-QGVYLGMPGCLPAYDALAGQFIEASSREARQAILKQGQDGLSGVKETDKKWASQYLKIMGKILDQGEDFPASELARISKLIEN-KMSEGKKEELQRSLNILTAFR-----KKGAEKEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57759-1", "uniprot_id": "ERP29_MOUSE", "id": "P57759-1", "name": "Endoplasmic reticulum resident protein 29", "aln": "MAAAAGVSGAASLSPLLSVLLGLLLLFAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENS-ASSEELLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFR-DGDLENPVLYNGAVKVGAIQRWLKG-QGVYLGMPGCLPAYDALAGEFIKASSIEARQAILKQGQDGLLSVKETEKKWASQYLKIMGKILDQGEDFPASEMARIGKLIEN-KMSDSKKEELQKSLNILTAFR-----KKEAEKEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30040-1", "uniprot_id": "ERP29_HUMAN", "id": "P30040-1", "name": "Endoplasmic reticulum resident protein 29", "aln": "--MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENS-ASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFR-DGDFENPVPYTGAVKVGAIQRWLKG-QGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQ-----KKGAEKEEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O44342-1", "uniprot_id": "WBL_DROME", "id": "O44342-1", "name": "Protein windbeutel", "aln": "------------MMHILVTLLLVAIHSIPT-TWAVTCTGCVDLDELSFEKTVERFPYSVVKFDIAYPYGEKHEAFTAFSKSAHKATKDLLIATVGVKDYGELENKALGDRYKVDDKNFPSIFLFKGNADEYVQLPSHVDVTLDNLKAFVSANTPLYIGRDGCIKEFNEVLKNYANIPDAEQLKLIEKLQAKQEQLTDPEQQQNARAYLIYMRKIHEVGYDFLEEETKRLLRLKAG-KVTEAKKEELLRKLNILEVFRVHKVTKTAPEKEEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* ** . : * .: .*.: ** ::* *.: : : :**** ******:: *. :::.: ::.:**:* **:.***: * *.::**:*.:.:* ::**: :.* : *.:. :: ::.. :*:* **: :: : :: . .. * : : * . .. ::: * ** * ** : * ** .* *: :* *:::.***** :.**** .*: *. .*****", "identical_positions": 73, "similar_positions": 88, "identity": "26.94%" }, { "cls_id": "homologset.agr.FB:FBgn0004045", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32PY2-1", "uniprot_id": "LIPH_RAT", "id": "Q32PY2-1", "name": "Lipase member H", "aln": "MLRLCFLLSFMCLVKS----------------DTDETCPSFTRLSFHSAVVG---TGLSVRLMLYTQRDQTCAQVIN---STALGSLNVTKKTTFIIHGFRPTGSPPVWMEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRKVALILKEFIDQMLAKGASLDNIYMIGVSLGAHIAGFVGEMYSGKLGRITGLDPAGPLFNGRPPEDRLDPSDAQFVDVIHSDTDALGYREALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVFLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGHIVSCPSLGYYADNWREYLWDRD---PPMTKAFFDTAETKPYCIYHYFVDIISWNKSVRRGFITIKLRG-EDGNITESKIDHEPSAFQKYHQVSLLARFNRDLDKVAEISLLFS-TKSVVGPKYKLRVLRMKLRS----LAHPDRPHLCRYDLVLMENVETFFQPILCSKQQM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIV3-1", "uniprot_id": "LIPH_MOUSE", "id": "Q8CIV3-1", "name": "Lipase member H", "aln": "MLRLCFFISFMCLVKS----------------DTDETCPSFTRLSFHSAVVG---TGLSVRLMLYTQRDQTCAQIIN---STALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVKGASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDALGYKEALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGQIVPCPRVGYYADSWKEYLWDRD---PPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRG-EDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFS-TGSVVGPKYKLRVLQMKLRS----LAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWY8-1", "uniprot_id": "LIPH_HUMAN", "id": "Q8WWY8-1", "name": "Lipase member H", "aln": "MLRFYLFISLLCLSRS----------------DAEETCPSFTRLSFHSAVVG---TGLNVRLMLYTRKNLTCAQTIN---SSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWKDHLRGKD---PPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRD-KAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFS-TGSLIGPRYKLRILRMKLRS----LAHPERPQLCRYDLVLMENVETVFQPILCPELQL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZMG4-1", "uniprot_id": "D3ZMG4_RAT", "id": "D3ZMG4-1", "name": "Lipase member H", "aln": "-MRIYTFLCWICWVRFGYLNFPSKSNGGSKNPENNRTCLEFSKSNAMNSLKDLFYPTVKINLLMYSRNNAKCAEPLFESNNSVNARFNPSKKTIWIIHGYRPLGSTPMWIHKFTKAFLKQEDVNLIVVDWNQGATTFIYGRAVKNTRKVAEILREYIENLLIHGASLDNFHFIGMSLGAHICGFVGKLFQGQLGRITGLDPAGPKFSGKPSNCRLDYTDAKFVDVIHSDSQGFGILEPSGHIDFYPNGGRNQPGCPTSLLSGMDYIKCDHQRAVHLFLEAFETNCNFVSFPCRSYRDYKSGLCVGCGNLYKDSCPRLGIQANLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALNETMKNGSLSFGLLK-DLGVLEYPRLYVKTMPFANLQEVKILAQFVNDIVNISRISMTYYQSTSPFCPTCEYRIKSLVFKS----LTHPERPPICKYDFVLKERARIDLQPDECKKQTG----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YQT7-1", "uniprot_id": "F6YQT7_MOUSE", "id": "F6YQT7-1", "name": "Lipase member H", "aln": "-MRIYIFLCLICWARFGYLNFQSNTTGVSKDPEKKRTCLEFTKLSAMNSLKDLFCPKVKINLLMYSRGNAKCAEPLFESNNSLNTRFNPAKKTVWIIHGYRPFGSTPVWLSRFTKAFLKQEDVNLIVVDWNQGATTFMYSRAVRNTRRVAEILRETIENLLIHGASLDNFHFIGMSLGAHISGFVGKIFHGQLGRITGLDPAGPQFSRKPSNSRLYYTDAKFVDVIHTDIKSLGIGEPSGHIDFYPNGGKHQPGCPTSIFSGTNFIKCDHQRAIYLFLAAFETSCNFVSFPCRSYKDYKNGLCVDCGNLYKDSCPRLGNQAKLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALSETMRNGSISFGLLN-DLGDLEYSTLYEKSKPFDNLQEVKILVQFVNDIVSISRICLTYFQSTNPYCAACQYKIQSLVLKS----LTYPERPPICKYNFVLKEGTRVDLQPDECNTQME----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XZB0-1", "uniprot_id": "LIPI_HUMAN", "id": "Q6XZB0-1", "name": "Lipase member I", "aln": "-MRVYIFLCLMCWVRS----------------DNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLN-QLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKS----LTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02843-1", "uniprot_id": "VIT1_DROME", "id": "P02843-1", "name": "Vitellogenin-1", "aln": "-MNPMRVLSLL-------------------------ACLAVAALAKPNGRMDNSVNQALKPSQWLSGSQLEAIPALDDFTIERLENMNLERGAELLQQVYHLS-----QIHHNVEPNYVPSGIQVYVPKPNGDKTVAPLNEMIQRLKQKQNFGEDEVTIIVTG---LPQTSETVKKATRKLVQAYMQRYNLQQQRQHGKN-GNQDYQDQSNEQRKNQRTSSEEDYSEEVKN---AKTQSGDIIVIDLGSKLN-TYERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQNVGAHVAG--AAAQEFTRLTGHKLRRVTGLDPSKIVAKS------KNTLTGLARGDAEFVDAIHTSVYGMGTPIRSGDVDFYPNGPAAGVPGASNVVEAAMRATRYFAESVRPGNERSFPAVPANSLQQYKQNDGFGKRAYMGIDTAHDLEGDYILQVNPKSPFGRNAPAQKQSSYHGVHQAWNTNQDSKDYQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:. : .* .: .. . : : . : :* : : : : :: : .. . ::: * . . . *. . . :: : :: * : . :: : : * * : .. :. :. * : * . . *.* . *. : : . . .. : : : . : . . . . : : : : ...: . : . .: . : * . : * . : . .: ..: :. : . : . * :. : : . : .: ", "identical_positions": 15, "similar_positions": 114, "identity": "3.09%" }, { "cls_id": "homologset.agr.FB:FBgn0004047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32PY2-1", "uniprot_id": "LIPH_RAT", "id": "Q32PY2-1", "name": "Lipase member H", "aln": "MLRLCFLLSFMCLVKS----------------DTDETCPSFTRLSFHSAVVG---TGLSVRLMLYTQRDQTCAQVIN---STALGSLNVTKKTTFIIHGFRPTGSPPVWMEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRKVALILKEFIDQMLAK-GASLDNIYMIGVSLGAHIAGFVGEMYSGKLGRITGLDPAGPLFNGRPPEDRLDPSDAQFVDVIHSDTDALGYREALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVFLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGHIVSCPSLGYYADNWREYLWDRD---PPMTKAFFDTAETKPYCIYHYFVDIISWNKSVRRGFITIKLRG-EDGNITESKIDHEPSAFQKYHQVSLLARFNRDLDKVAEISLLFS-TKSVVGPKYKLRVLR-MKLRSLAHPDRPHLCRYDLVLMENVETFFQPILCSKQQM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIV3-1", "uniprot_id": "LIPH_MOUSE", "id": "Q8CIV3-1", "name": "Lipase member H", "aln": "MLRLCFFISFMCLVKS----------------DTDETCPSFTRLSFHSAVVG---TGLSVRLMLYTQRDQTCAQIIN---STALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVK-GASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDALGYKEALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCGAGQIVPCPRVGYYADSWKEYLWDRD---PPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRG-EDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFS-TGSVVGPKYKLRVLQ-MKLRSLAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWY8-1", "uniprot_id": "LIPH_HUMAN", "id": "Q8WWY8-1", "name": "Lipase member H", "aln": "MLRFYLFISLLCLSRS----------------DAEETCPSFTRLSFHSAVVG---TGLNVRLMLYTRKNLTCAQTIN---SSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAE-GASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWKDHLRGKD---PPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRD-KAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFS-TGSLIGPRYKLRILR-MKLRSLAHPERPQLCRYDLVLMENVETVFQPILCPELQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZMG4-1", "uniprot_id": "D3ZMG4_RAT", "id": "D3ZMG4-1", "name": "Lipase member H", "aln": "-MRIYTFLCWICWVRFGYLNFPSKSNGGSKNPENNRTCLEFSKSNAMNSLKDLFYPTVKINLLMYSRNNAKCAEPLFESNNSVNARFNPSKKTIWIIHGYRPLGSTPMWIHKFTKAFLKQEDVNLIVVDWNQGATTFIYGRAVKNTRKVAEILREYIENLLIH-GASLDNFHFIGMSLGAHICGFVGKLFQGQLGRITGLDPAGPKFSGKPSNCRLDYTDAKFVDVIHSDSQGFGILEPSGHIDFYPNGGRNQPGCPTSLLSGMDYIKCDHQRAVHLFLEAFETNCNFVSFPCRSYRDYKSGLCVGCGNLYKDSCPRLGIQANLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALNETMKNGSLSFGLLK-DLGVLEYPRLYVKTMPFANLQEVKILAQFVNDIVNISRISMTYYQSTSPFCPTCEYRIKS-LVFKSLTHPERPPICKYDFVLKERARIDLQPDECKKQTG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YQT7-1", "uniprot_id": "F6YQT7_MOUSE", "id": "F6YQT7-1", "name": "Lipase member H", "aln": "-MRIYIFLCLICWARFGYLNFQSNTTGVSKDPEKKRTCLEFTKLSAMNSLKDLFCPKVKINLLMYSRGNAKCAEPLFESNNSLNTRFNPAKKTVWIIHGYRPFGSTPVWLSRFTKAFLKQEDVNLIVVDWNQGATTFMYSRAVRNTRRVAEILRETIENLLIH-GASLDNFHFIGMSLGAHISGFVGKIFHGQLGRITGLDPAGPQFSRKPSNSRLYYTDAKFVDVIHTDIKSLGIGEPSGHIDFYPNGGKHQPGCPTSIFSGTNFIKCDHQRAIYLFLAAFETSCNFVSFPCRSYKDYKNGLCVDCGNLYKDSCPRLGNQAKLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALSETMRNGSISFGLLN-DLGDLEYSTLYEKSKPFDNLQEVKILVQFVNDIVSISRICLTYFQSTNPYCAACQYKIQS-LVLKSLTYPERPPICKYNFVLKEGTRVDLQPDECNTQME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XZB0-1", "uniprot_id": "LIPI_HUMAN", "id": "Q6XZB0-1", "name": "Lipase member I", "aln": "-MRVYIFLCLMCWVRS----------------DNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKH-GASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLN-QLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQS-LMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06607-1", "uniprot_id": "VIT3_DROME", "id": "P06607-1", "name": "Vitellogenin-3", "aln": "--MMSLRICLLAT------------------------CLLVAAHASKDASND----RLKPTKWLT---------------ATELENVPSLNDITWERLENQPLEQGAKVIEKIYHVGQIKHDLTPSFVPSPSNVPVWIIK---SNGQKVECKLNNYVETAKAQPGFGEDEVTIVLTGLPKTSPAQQKAMRRLIQAYVQKYNLQQLQKNAQEQQQQLKSSDYDYTSSEEAADQWKSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLIDLTNKGVPQ--EIIHLIGQGISAHVAG--AAGNKYTAQTGHKLRRITGLDPAKVLSKR------PQILGGLSRGDADFVDAIHTSTFAMGTPIRCGDVDFYPNGPSTGVPGSENVIEAVARATRYFAESVRPGSERNFPAVPANSLKQYKEQDGFGKRAYMGLQIDYDLRGDYILEVNAKSPFGQRSPAHKQAAYHGMHHAQN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :. * .: .: . :. : : . :. : :* . . : : : .::. .* .... : : ::* * :. . * . *:. :: .* . . : : . : :* :* :.. .: . . . *.: : *. :::. . * : * .. : . : . . . . : : : : . : . : . . . . : * . : . * : . .: .:: :. : . : ::. : . :. . : ", "identical_positions": 16, "similar_positions": 118, "identity": "3.33%" }, { "cls_id": "homologset.agr.FB:FBgn0004049", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYE5-1", "uniprot_id": "E41LB_RAT", "id": "B2RYE5-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR--------------------------------RHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPN---VSN----HSTCKQNK--PSF---QDDRP-------HWKASASGDDGHFDYVHDQN--------------------QRNLGGAYSVTYR------------DKLMTAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMC8-1", "uniprot_id": "E41LB_MOUSE", "id": "Q9JMC8-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHAKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR--------------------------------RHSTFKASNPVIAAQLCSKANPEVHNYQPQYHPDVHPSQPRWRPHSPN---VSN----HSICKQNK--PCF---QDDRP-------HWKTSASGDGSHFDYVQDQN--------------------QRNLGGAYSVTYR------------DKLMTAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H329-1", "uniprot_id": "E41LB_HUMAN", "id": "Q9H329-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR--------------------------------RHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHPSQPRWHPHSPN---VSYPLPSPVLSSSDR--LPFGIEENGGT-------PFLTAASGRHHHQHQHQHQH--------------------QHHSNYSLSLTLENKEGPLRSPNSSSKSLTKLSPGTPALFS---EAAAHLKKLELETVKAAGPWPPLH----------------ININ-KAEEKKVSEKTLQTPLLPSPV-----ADHVKCNILKAQLENASRVNIQGGKEESPFVNINKKSSLQDASVRSPIPIRVETAQPAVEKPEIKPPRVR-KLTRQYSFDEDDLPPDLAEAVGVTT---------------------STTTNTTTAATQVSVPLPSPKVQNVSSPHKSEGKGLLSPGAKSPSDRGGAFTLEPGDLLMDFTEATPLAEPASNPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPVDTMNPFPDTFTTGPQFTADFRDSKLQCCPGPTSPLIPAATLRPLTETVSTVQTIYTTRKPVSLAASAETLRQELEREKMMKRLLMTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4V0-1", "uniprot_id": "A0A8M2B4V0_DANRE", "id": "A0A8M2B4V0-1", "name": "", "aln": "MMGFLRRTFSRRS-KRNARPPS--EVDGTGNVRGG-----------NAVLQAHQQQVIHAP---TVVTGGAVVHIPAAGNSKDAITCRVLLLDGSDVNVELPKHAKGQDLFDQIMYHLDLVEADYFGLQFMDPEQVAHWLDAAKPIKKQIRHGPPYRLFFRVKFYSSEPNNLHEEFTRYLFVLQLRQDILSGKLKCPYDVSVELGAYCLQSELGDCDPLEHSILLVSEFRFSPKQTEIMEADIYRKWVECRGMIPSQAELNFLNKCKWLEMYGVDMHFVKGRDGGEYALGLTPTGILVFEGSSKIGLFFWPKITRLDFKRNRLTLVVVEDDEKGREQEHTFVFQLSSSHECKHLWKCAVESHAFFRLRQPTHNKTSRSDFTRLGSRFRFSGRTEYQATHSGKVRRASTFERRPSKRYPSR--------------------------------AQSMVKAMTPAKHPHLSAQTSPEPS--LKPYKHNIPIAQDPWQRSHPPPSLTSPLYIQPMELGHTP--PPHSFPLSAAD-------TRRFSVEENEAPHSGKIHRC--------------------YHHHGYEKQEPLC-----------LTTAKPKAWVVSPALSD---ELDRALQN-QLEAEPAA--WPALH----------------INID-MAEEKPLSEKSLPS--SPAVL-----QEQLKSNISKRATQSDS-------------GNSKGNSSSGDQTDRYPSSS-QDSGSSSLNIEKPRVDRRK-RLVRQFSFNHSDED-DLPEALAAIS---------------------SQCS------------------MGKSSSNSSLDKQVQPP-----------------------------------------------------------IYPPQKD-----------------------TSRLEHDSSPLFFPSPVPHLLPYATHTQ----------------------SSEDLR--MEREKLLRALLMTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5FVG2-1", "uniprot_id": "E41L5_RAT", "id": "Q5FVG2-1", "name": "Band 4.1-like protein 5", "aln": "MLSFLRRTLGRRSMRKHAEKER---------------------------LREAQR---------------AATHIPAAGDAKSVITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPTQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKGSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRR--------------------------------TLQVKGEVWPCSTGSVHN-ASAQNNDSQQAWGMKSPVPVTSFSSSGPVLVETENLPQNSAADQHDRKRLPLSIDLLNSP-------DLLETTIGDVTRPSDTSAPF--------------------PAPDDVNVATMSH--------------ELEELRADCETLKD---DTEK-LKQLNTEQNILPSLRPAID----------------INVNSQEEVVKLTEKCLNNAIESPGLNTVRVPPDFKSNILKAQVEAVH------------------KATREDSLLTHKNASVQDAATNSTVFNENNMPLCKDSLTPVHG-TTADSDSVLKDATDELD---------------------ALLLSLTEN------------LMDHTVTPQVSSSSMITPR---------------------------------------------------------WIIPQNSTIS---------NGLAGYGVSLTGTEGCNQKDGFSLISPPAPFLVDAVTS------------------------SAPPLP--GDSALKQKCLLTTEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGS1-1", "uniprot_id": "E41L5_MOUSE", "id": "Q8BGS1-1", "name": "Band 4.1-like protein 5", "aln": "MLSFLRRTLGRRSMRKHAEKER---------------------------LREAQR---------------AATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRR--------------------------------TLQMKASTTQPEDLGVLN-ASAQKSDSQQAWGVMSPVPVTSSSSCGAVQVEIENLPQTSATEQHDRKCLPLSVDLLNSP-------DLLETTIGDVTRTSETSAPF--------------------PAPDTINVATRSN--------------ELEEFKAECETLKD---DTEK-LKQLETEQTILPSLRPTID----------------INVNSQEEVVKLTEKCLNNAIENPALNAVKVPPDFKSNILKAQVEAVH------------------KVTREDSLLTHKNASVQDAATNSTAFNENDVPVCKDSLTPVHG-TAADSASVLKDATDELD---------------------ALLLSLTEN------------LMDHTVTPQVSSPSMITPR---------------------------------------------------------WIIPQSATIS---------NGLAGYGASLAGTDECSQKDGFSLISPPAPFLVDAVTS------------------------SAPPLP--EDSTLKQKCLLTTEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCM4-1", "uniprot_id": "E41L5_HUMAN", "id": "Q9HCM4-1", "name": "Band 4.1-like protein 5", "aln": "MLSFFRRTLGRRSMRKHAEKER---------------------------LREAQR---------------AATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRR--------------------------------TLQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQHDRKCIPLNIDLLNSP-------DLLEATIGDVIGASDTMETS--------------------QALNDVNVATRLP--------------GLGEPEVEYETLKD---TSEK-LKQLEMENSPLLSPRSNID----------------VNINSQEEVVKLTEKCLNNVIESPGLNVMRVPPDFKSNILKAQVEAVH------------------KVTKEDSLLSHKNANVQDAATNSAVLNENNVPLPKESLETLMLITPADSGSVLKEATDELD---------------------ALLASLTEN------------LIDHTVAPQVSSTSMITPR---------------------------------------------------------WIVPQSGAMS---------NGLAGCEMLLTGKEGHGNKDGISLISPPAPFLVDAVTS------------------------SGPILA--EEAVLKQKCLLTTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFU8-1", "uniprot_id": "Q9VFU8_DROME", "id": "Q9VFU8-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "MLRFLSRRKVRNNYVDNSREGGG---------------------ATSSAVGVAGGGGAITSG------GSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGRTEFQTTQQSRARRTVQFERRPSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATPLVSSQVSTPTPNNDNNNDAFDSLISTDQFITVTPSPSVLTVIQNSAIIEPDAACSGSISSSSQAAANFASLGRNSLKSNFSNEDPAYSKIGSIGKASGLTVKLDPDYTPPYSPNATKNFDETNPFRNATSSHHGSFGKASISSGQLSVKSGLSDKDRELDSLLKSIVKDPSPSVLANEAINDANSIRVTINKTFDMDHNTETLKRLSNANEKPNNQVKLANVNTTALPPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHAHSDGPDSLNATYISVGGDKLTLSIPEQKPSTGSSSSSSTSSTATTTTNGNGPYSNATFVSGFSAPLTPPSSLPANLNNTGSGCNTTLTSVTTISTPSSPTATVSTTASESVAPALSNASAAEILINEIFINNIINNNASGSITAETAAKPAGSSTPSAGTLLFSTLSEQERLESQKTNQQMNQSLNLNQNHSEVDAPPSEKKTPSNYPDSSRIPFPSSSNSK------------DMVSPWLVSSEVVSAPKGRESAIIRKSVITTQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: * *.. :. : : : * : *** ***.:::.::*.*:* *. *::*:.* **::* *****:*:*. :* **** :*.****:: *..* : ::**:******.*:**:*****.***::*:*.*:*.** : :.:* * **:***: : **: ****** * *** :* * .: ** *:*** :***.***:******* * .:** :* *******:*:** **********:::***:.:***:*:***::*:********:* : ********** *:***** * : : *..* *:*****:**:**:*:*: .: **: ***:**:*:. * .. . . : ", "identical_positions": 189, "similar_positions": 106, "identity": "18.69%" }, { "cls_id": "homologset.agr.FB:FBgn0004053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6RGM2-1", "uniprot_id": "B6RGM2_RAT", "id": "B6RGM2-1", "name": "", "aln": "MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFF------IPLGMPSPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHS-SRPPAGAGGGATGTAGAAVAGGGVAGGTGALP----LLKSQFSPGPGDAQFCPRVSHAHHHHHAPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHH-------------------APVCAATTYNVSDPRRFHCLTMGGSDTS-----------QVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNR--RVKHKKEGKGASRNNHASCKCVGSQAHYARSEDEDSLSPASANEDKEISPL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31316-1", "uniprot_id": "GSX2_MOUSE", "id": "P31316-1", "name": "GS homeobox 2", "aln": "MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFF------IPLGMPSPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHS-SRPPAGAGGGATGTAGAAVAGGGVAGGTGALP----LLKSQFSPAPGDAQFCPRVSHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHH-------------------APVCAATTYNMSDPRRFHCLSMGGSDTS-----------QVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNR--RVKHKKEGKGASRNNHTSCKCVGSQAHYARSEDEDSLSPASANEDKEISPL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZM3-1", "uniprot_id": "GSX2_HUMAN", "id": "Q9BZM3-1", "name": "GS homeobox 2", "aln": "MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFF------IPLGMPPPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHS-SRGSVGAGSGGAGAGVTGAGGSGVAGAAGALP----LLKGQFSSAPGDAQFCPRVNHAHHHHHPPQHHHHHHQPQQPG-SAAAAAAAAAAAAAAAALGHPQHH-------------------APVCTATTYNVADPRRFHCLTMGGSDAS-----------QVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNR--RVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKEISPL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09089-1", "uniprot_id": "ZEN1_DROME", "id": "P09089-1", "name": "Protein zerknuellt 1", "aln": "MSSVMHYYPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQTTAAPQVSTATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKSAPILATQSWHPSSQSQVPTSVHAAPSMNLSWGEPAAKSRKLSVNHMNPCVTSYNYPN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: .: . . :.. .* : . :: *:*:*. *.* . :... * *:*. : *: .: . :. . :. . : * : : . .:* * : .::: :.::. : ::* * * . * :* . : : : *** . . *: :: : .. : .* :* *.. . :: ** :** . . **. : * : : : : * .: * :.: : .:. : :.:.. . . .... : : .* . *.*. : . ", "identical_positions": 39, "similar_positions": 115, "identity": "11.05%" }, { "cls_id": "homologset.agr.FB:FBgn0004054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09090-1", "uniprot_id": "ZEN2_DROME", "id": "P09090-1", "name": "Protein zerknuellt 2", "aln": "------MFAIQ-------------------SENYFVDNYSVSDLMMYP------------------CVELNVEAAPT---------ATTRSSEKSKRSRTAFSSLQLIELEREFHLNK--YLARTRRIEISQRLALTERQVKIWFQNRR------MKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTN-VETAPLRQ----VDHGVLEEGQ-ITPPYQSYDYLHEFSPEPMALPQLPFNEFDANWASSWLGLEPTIPIAENVIEHNTQDQPMIQN-----FCWDSNSSSASSSDILDVDYDFIQNLLNF--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9BZM3-1", "uniprot_id": "GSX2_HUMAN", "id": "Q9BZM3-1", "name": "GS homeobox 2", "aln": "---MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSRG---------SVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKGQFSSAPGDAQFCPRVNHAHHHHHPPQHHHH------HHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVADPRRFHCLTMGG----SDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSEDEDSLSPASANDDKEISPL-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34161-1", "uniprot_id": "YOX1_YEAST", "id": "P34161-1", "name": "Homeobox protein YOX1", "aln": "MSQETKMLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVESALRHTVTSLHENSSAYGDDMLKHTQSDSALSSQLNSSQETVDESHENLLLTPLNSKKRDYSVSSKKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQRIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSSSSPLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRVNKLINSIDHSPSKAKRPVSNPSGSPKRKRKFGFKIVDQQPLKDLDPNAFRG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : . : .:: : * . . : * : . :: : :. :.: :.. :. . :. . . . . : : . : . :: : * .:..... .. . . . . . : : : ", "identical_positions": 3, "similar_positions": 61, "identity": "0.78%" }, { "cls_id": "homologset.agr.FB:FBgn0004057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00612-1", "uniprot_id": "G6PD1_MOUSE", "id": "Q00612-1", "name": "Glucose-6-phosphate 1-dehydrogenase X", "aln": "-------------------MAEQVALSRTQVCGILREELYQGDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPEDTFIVGYARSRLTVDD-IRKQSEPFFKATPEER--PKLEEFFARNSYVAGQYDDAASYKHLNSHMNALHQGM---QANRLFYLALPPTVYEAVTKNIQETCMSQTGWNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPATTGSDDVRDEKVKVLKCISEVETDNVVLGQYVGNPNGE-GEAANGYLDDPTVPHGSTTATFAAAVLYVENERWDGVPFILRCGKALNERKAEVRLQFRDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHKIDR-EKPQPIPYVYGSRGPTEADELMKRVGFQY--EGTYKWVNPHKL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05370-1", "uniprot_id": "G6PD_RAT", "id": "P05370-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "-------------------MAEQVALSRTQVCGILREELYQGDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPEDTFIVGYARSRLTVDD-IRKQSEPFFKVTPEER--PKLEEFFARNSYVAGQYDDPASYKHLNSHMNALHQGM---QANRLFYLALPPTVYEAVTKNIQEICMSQTGWNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTDSDDVRDEKVKVLKCISEVETDNVVLGQYVGNPSGE-GEATNGYLDDPTVPHGSTTATFAAAVLYVENERWDGVPFILRCGKALNERKAEVRLQFRDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHKIDR-EKPQPIPYVYGSRGPTEADELMKRVGFQY--EGTYKWVNPHKL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97324-1", "uniprot_id": "G6PD2_MOUSE", "id": "P97324-1", "name": "Glucose-6-phosphate 1-dehydrogenase 2", "aln": "-------------------MAEQVTLSRTQVCGILREELYQNDAFHQADTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPKETFIVGYARSQLTVDD-IQKQSEPFFKATPEER--PKLEEFFTRNSYVVGQYDDPASYKHLNSYINALHQGM---QANHLFYLALPPTVYEAVTKNIQETCMSQTGFNRIIVEKPFGRDLQSSNQLSNHISSLFREDQIYRIDHYLDKEMVQNLMVLRFANRIFGPIWNGDNIVCVILTFKEPFGTEGRGGYFDEFGIIRDVMQSHLLQMLCLVAMEKPATTDSDDVRNEKVKVLKCISEVETDNVILGQYVGNPNGE-GEAANGYLDDPTVPRGSTTATFAAAVLYVKNERWDGVPFILRCGKALNERKAEVRLQFRDIPGDIFHQKCKRNELVIRMQPNEAVYTTMMTKKPGMFFNPEESELDLTYGNKYKNVKLPGAYERLILDVFCGCQMHFVRTDELREGWRIFTPLLHKIER-EKPQPFPYVYGSRGPTEADELMRRVGFQY--KGTYKGTHKH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11413-1", "uniprot_id": "G6PD_HUMAN", "id": "P11413-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "-------------------MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVAD-IRKQSEPFFKATPEEK--LKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGS---QANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGE-GEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIEL-EKPKPIPYIYGSRGPTEADELMKRVGFQY--EGTYKWVNPHKL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B959-1", "uniprot_id": "A0A8M2B959_DANRE", "id": "A0A8M2B959-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "MMGSRASAERAHTTVPTHSDKMSLPLSRSEVFGQLRKELHDDTAFHQSDVHIFIIMGASGDLAKKKIYPTLWWLFRDGLLPEQTYFVGFARSDLTVDA-IRIACMPYMKVVDNEA--ERLAAFFSRNSYISGKYVEESSFSDLNTHLLSLPGGA---EANRLFYLALPPSVYHDVTKNIKHQCMSTKGWNRVIVEKPFGRDLQSSEELSSHLSSLFTEEQIYRIDHYLGKEMVQNLMVLRFGNRIFGPIWNRDSVACVVLTFKEPFGTQGRGGYFDDFGIIRDVMQNHLLQMLSLVAMEKPASTSSDDVRDEKVKVLKCIEPVTLSDVVLGQYVGDPDGE-GEAKLGYLDDKTVPKGSTQATFATAVLYVKNERWDGVPFILRCGKALNERKAEVRLQFTDVPGDIFSSQCRRNELVVRVQPNEAIYAKMMSKKPGVYFSPEETELDLTYHSRYRDVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIES-EKTPPIKYKYGSRGPAEADELVQKVGFRY--EGTYKWVNPHKL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12646-1", "uniprot_id": "G6PD_DROME", "id": "P12646-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "---------------MATQKEDHTALDLIIKSLKSPTMVCEGTHFDGKIPHTFVIFGASGDLAKKKIYPTLWWLYRDDLLPKPTKFCGYARSMLTVDS-IKEQCLPYMKVQPHEQ--KKYEEFWALNEYVSGRYDGRTGFELLNQQLEIMENKN---KANRIFYLALPPSVFEEVTVNIKQICMSVCGWNRVIIEKPFGRDDASSQALSDHLAGLFQEDQLYRIDHYLGKEMVQNLMTIRFGNKILSSTWNRENIASVLITFKEPFGTQGRGGYFDEFGIIRDVMQNHLLQILSLVAMEKPVSCHPDDIRDEKVKVLKSIEALTLDDMVLGQYLGNPQGTNDDARTGYVEDPTVSNDSNTPTYALGVLKINNERWQGVPFILRCGKALNERKAEVRIQYQDVPGDIFEGNTKRNELVIRVQPGEALYFKMMTKSPGITFDIEETELDLTYEHRYKDSYLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPILHQIEK-EHIRPITYQYGSRGPKEADRKCEENNFKY--SGSYKWHGGKAATSNH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11412-1", "uniprot_id": "G6PD_YEAST", "id": "P11412-1", "name": "Glucose-6-phosphate 1-dehydrogenase", "aln": "--------------------------------------MSEGPVKFEKN-TVISVFGASGDLAKKKTFPALFGLFREGYLDPSTKIFGYARSKLSMEEDLKSRVLPHLKKPHGEADDSKVEQFFKMVSYISGNYDTDEGFDELRTQIEKFEKSANVDVPHRLFYLALPPSVFLTVAKQIKSRVYAENGITRVIVEKPFGHDLASARELQKNLGPLFKEEELYRIDHYLGKELVKNLLVLRFGNQFLNASWNRDNIQSVQISFKERFGTEGRGGYFDSIGIIRDVMQNHLLQIMTLLTMERPVSFDPESIRDEKVKVLKAVAPIDTDDVLLGQYGKSEDGS----KPAYVDDDTVDKDSKCVTFAAMTFNIENERWEGVPIMMRAGKALNESKVEIRLQYKAVASGVFKDIPN-NELVIRVQPDAAVYLKFNAKTPGLSNATQVTDLNLTYASRYQDFWIPEAYEVLIRDALLGDHSNFVRDDELDISWGIFTPLLKHIERPDGPTPEIYPYGSRGPKGLKEYMQKHKYVMPEKHPYAWPVTKPEDTKDN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : ::********** :*::: *:*:. * * : *:*** *:: :: *.:* * : *: .*: *.* .:. *. : : .:::*******:*: *: :*: : * .*:*:*****:* *: *..::. ** *:::*******.**:*:**:.:**.*:::.. ** :.: .* ::*** ***:*******.:********.****:: *::**:*.: .:.:*:*******.: : .:::**** . .* .*::* ** ..*. *:* .: ::****:***:::*.****** *.*:*:*: :...:* . ****:*:**. *:* .: :*.**: : ::*:*** :*:: :* *** ** *.: * : :*** *** .* ****:*::*: : * * ****** .. .. : . .* : ", "identical_positions": 185, "similar_positions": 159, "identity": "33.7%" }, { "cls_id": "homologset.agr.FB:FBgn0004066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6I7-1", "uniprot_id": "F1M6I7_RAT", "id": "F1M6I7-1", "name": "Proteasome subunit alpha type", "aln": "MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVR-KICALDDHVCMAFA------GLTADARVVISRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDD-DGIPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNY-TEDAISNDNEAIKLAIKALLEVVQSGGKNIELAIIRRDQPLKMFSAKEIELEVTEIEREKDE-AEKKKSKKST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWH6-1", "uniprot_id": "PSMA8_MOUSE", "id": "Q9CWH6-1", "name": "Proteasome subunit alpha type-8", "aln": "MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVR-KICALDDHVCMAFA------GLTADARVVISRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDD-DGIPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNY-TEDAISNDKEAIKLAIKALLEVVQSGGKNIELAIIRRDQPLKMFSAKEIELEVSEIEREKDE-AEKTKSKKST-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAA3-1", "uniprot_id": "PSMA8_HUMAN", "id": "Q8TAA3-1", "name": "Proteasome subunit alpha-type 8", "aln": "MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVR-KICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDD-DGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNY-TEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEE-AEKKKSKKSV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14818-1", "uniprot_id": "PSA7_HUMAN", "id": "O14818-1", "name": "Proteasome subunit alpha type-7", "aln": "MS--YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR-KICALDDNVCMAFA------GLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDF-DGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY-TDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEE-NEKKKQKKAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48004-1", "uniprot_id": "PSA7_RAT", "id": "P48004-1", "name": "Proteasome subunit alpha type-7", "aln": "MS--YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR-KICALDDNVCMAFAVVASVSGLTADARIVINRARVECQSHRLTVGDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDF-DGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY-TDDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILSPEEIEKYVAEIEKEKEE-NEKKKQKKAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2U0-1", "uniprot_id": "PSA7_MOUSE", "id": "Q9Z2U0-1", "name": "Proteasome subunit alpha type-7", "aln": "MS--YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR-KICALDDNVCMAFA------GLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDF-DGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY-TDDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEE-NEKKKQKKAS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22769-1", "uniprot_id": "PSA71_DROME", "id": "P22769-1", "name": "Proteasome subunit alpha type-7-1", "aln": "MSSRYDRAVTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKKSVAQLQEDRKVR-KICMLDNHVVMAFA------GLTADARIMINRAQVECQSHRLNVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGISCLIGGFDA-DGSAHLFQTEPSGIFYEYKANATGRSAKVVREFFEKSY-REEEVANEHGAVKLAIRALLEVAQSGQNNLEVAIMENGKPLKMLDTDVITDYVKIIEKEKEEELEKKKQKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40303-1", "uniprot_id": "PSA4_YEAST", "id": "P40303-1", "name": "Proteasome subunit alpha type-4", "aln": "MSG-YDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFS------GLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQIEQEKQEQQEQDKKKKSNH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ****:::******::***** ***::*: ***::* : **** *::*. :**: * . *:. :*.:* ::*: **.**:*::*.:*:**.***:*.: ****:**:**::* ::*:****.* ****:* ** *** *. .:*:**:*** : :.*:: **.:* ****:**.* .: . :**.:::****.*:* :*:*::::. .. : :... : * **:**:* *: *.** ", "identical_positions": 113, "similar_positions": 89, "identity": "43.3%" }, { "cls_id": "homologset.agr.FB:FBgn0004087", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920D2-1", "uniprot_id": "DYR_RAT", "id": "Q920D2-1", "name": "Dihydrofolate reductase", "aln": "--------MVRPLNCIVAVSQNMGIGKNGDLPWPLLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEP----PQGAHFLAKSLDDALKLIEQPELASKVDMVWVVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPE--YPGVLSEIQ-----------------EEKGIKYKFEVYEKKD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00375-1", "uniprot_id": "DYR_MOUSE", "id": "P00375-1", "name": "Dihydrofolate reductase", "aln": "--------MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEP----PRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPE--YPGVLSEVQ-----------------EEKGIKYKFEVYEKKD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00374-1", "uniprot_id": "DYR_HUMAN", "id": "P00374-1", "name": "Dihydrofolate reductase", "aln": "--------MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEP----PQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPE--YPGVLSDVQ-----------------EEKGIKYKFEVYEKND-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86XF0-1", "uniprot_id": "DYR2_HUMAN", "id": "Q86XF0-1", "name": "Dihydrofolate reductase 2, mitochondrial", "aln": "--------MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINLVLSRELKEP----PQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPE--YPGVLSDVQ-----------------EGKHIKYKFEVCEKDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWC6-1", "uniprot_id": "Q1LWC6_DANRE", "id": "Q1LWC6-1", "name": "dihydrofolate reductase", "aln": "MMNIEGEEMRKPIRLIAAACRDMGIGKDGQIPWC-LPKEFQFLLDTITAVSAPGKKNLIVWGRICWFSCPETVFPLANCINLVLSRKMISV----PPHAHYLCKDFDSIIRLVSEPPLCHTVEVIWILGGTEVYKESLEHPWCDLIYLTDIMANFECDVFFPEFDPNIFRKQKS--FPGVPDEII-----------------EENGIKFQFQVFKKIKN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17719-1", "uniprot_id": "DYR_DROME", "id": "P17719-1", "name": "Dihydrofolate reductase", "aln": "--------MLR-FNLIVAVCENFGIGIRGDLPWR-IKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVPESKRPLPDRLNIVLSTTLQESD---LPKGVLLCPNLETAMKILEEQ---NEVENIWIVGGSGVYEEAMASPRCHRLYITKIMQKFDCDTFFPAIP-DSFREVAP--DSDMPLGVQ-----------------EENGIKFEYKILEKHS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07807-1", "uniprot_id": "DYR_YEAST", "id": "P07807-1", "name": "Dihydrofolate reductase", "aln": "----MAGGKIPIVGIVACLQPEMGIGFRGGLPWR-LPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESN-FKEHLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYCFEFTLYNRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. ::*** * :* : .*:::: . . *:* :: *: : . * . ** . :*:::* : . . . .: : . :: ::::** **.: : : : . .: . : . . . * : ::: : :: ", "identical_positions": 19, "similar_positions": 61, "identity": "8.68%" }, { "cls_id": "homologset.agr.FB:FBgn0004101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHH8-1", "uniprot_id": "D3ZHH8_RAT", "id": "D3ZHH8-1", "name": "Serum response factor", "aln": "MLPSQAGAAAALGRGSALGGSLNRTPTGRPGG--SGGTRGANGGRVPGNGAGLGPGRLEREAAAAAA----PTAGALYSGSEGDSESGEEEE--------------LGAERRGLKRSLS------------EMELGVVVGGPEAAAAAAGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPSTDQRMSATGFEEPDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQT---------APSTSTTMQVSS-GPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVA---QQVPVQAIHVH----QAPQQAS--------------------------------------------PSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQAGSSS-NLTELQVVNLDATHSTKSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM73-1", "uniprot_id": "SRF_MOUSE", "id": "Q9JM73-1", "name": "Serum response factor", "aln": "MLPSQAGAAAALGRGSALGGNLNRTPTGRPGG--GGGTRGANGGRVPGNGAGLGQSRLEREAAAAAA----PTAGALYSGSEGDSESGEEEE--------------LGAERRGLKRSLS------------EMELGVVVGGPEAAAAAAGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEEPDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQT---------APSTSTTMQVSS-GPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVA---QQVPVQAIHVH----QAPQQAS--------------------------------------------PSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQAGSSS-NLTELQVVNLDATHSTKSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11831-1", "uniprot_id": "SRF_HUMAN", "id": "P11831-1", "name": "Serum response factor", "aln": "MLPTQAGAAAALGRGSALGGSLNRTPTGRPGG--GGGTRGANGGRVPGNGAGLGPGRLEREAAAAAATTPAPTAGALYSGSEGDSESGEEEE--------------LGAERRGLKRSLS------------EMEIGMVVGGPEASAAATGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQT---------APSTSTTMQVSS-GPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVA---QQVPVQAIQVH----QAPQQAS--------------------------------------------PSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLGDGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTASSGTVQIPVSAVQLHQMAVIGQQAGSSS-NLTELQVVNLDTAHSTKSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8HAM3-1", "uniprot_id": "A8HAM3_DANRE", "id": "A8HAM3-1", "name": "Serum response factor", "aln": "-MLGGNGTARGAGR-SGNGTGLTPLQVGSTSG--ALG--AVNSVINLPDGGRYDDG---------------PSVEAVLSGSDGDSDSGDDEES-------------PVPDRRGVKRERS------------ELEVGGSSG---SNAALSAGYGGVSSGVAGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRTDPSTDQRMSATGFEETDLTYQVSEADGLTEPKEMLKPTFTAATLPGGTNTISTTTQSPVSSSPSSSSVAMHTQSSGPSLSGT-TCWPVAAGMNAQSISSANGTVLKS------SSAGMMQLPSGFTLMPGASLPPGTHTVPLSQLQTHSLAIQCPQTQANSSGSTAVPAHTQPAALFRLPAAVSLTGGAMPQQLQAIQVHPSPQSSDSSPEISQTSSSATASHTATIVTSSVPSSVAGHMMYPGAHVMYATSTPALTDGGLTVLSAFPQPPSAMHVSHTPNQDSGGVPQMFLTGPPGTVQIPVSAVPLHSMLINQQPSGSSSSTLTELRVVNLDNPKGD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24535-1", "uniprot_id": "SRF_DROME", "id": "Q24535-1", "name": "Serum response factor homolog", "aln": "-MDPTRGDSRYNLNYSMSSIGLSLADPADMYGNPALGAGRPPSGGLLQNMGGVPPMQRPNPAAGAPP---APQCQTLHSPQHASQQQQQQQQQQQQHQQQQQQQQQHPQQQRGLKRSGSDCYEDHHRSSGGLTLQGLDNVASGAVDDSVDNYNPLPNKKSPPANGKKTKGRVKIKMEYIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVMLLVASETGHVYTFATRKLQPMITSEAGKQLIQTCLNSPDPP--SVGGGDQRMSATGFEETELSYNIADEDS----KDDRSPTSSGNESDDSSDVEMP---------AEAAEVATKLPA-----SKTEVSAPPAASCSAATASSGH------------------------------------KTMPALNYQTD---------------------------------------------------------TNSGPSTSTAAGGGGSADSKYVYSAASIANIPQKMLRQLIQSGHLQVHAEEDGNQYVTIPLSSTAANLIKSNKLTASGSGASGSGTPVKNDASADKPLTIKQEFD--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11746-1", "uniprot_id": "MCM1_YEAST", "id": "P11746-1", "name": "Pheromone receptor transcription factor", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MSDIEEGTPTNNGQQKERRKIEIKFIENKTRRHVTFSKRKHGIMKKAFELSVLTGTQVLLLVVSETGLVYTFSTPKFEPIVTQQEGRNLIQACLNAPDDEEEDEEEDGDDDDDDDDDGNDMQRQQPQQQQPQQQQQVLNAHANSLGHLNQDQVPAG---------ALKQEVKSQLLG---------GANPNQNSMIQQQQHHTQ------------------------------------NSQPQQQQQQQ--------------------------------------------------------------PQQQMSQQQMSQHPRPQQGIPHPQQSQPQQQQQQQQQLQQQQQQQQQQPLTGIHQPHQQAFANAASPYLNAEQNAAYQQYFQEPQQGQY-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : * **::::*:** **:.****** ******:***.******:***.**** ****:* *::*::*.: *: ***:***:** .: . . : :: : .: : :: .. . . .. . .. : . * . : : * : . : . . : : . . .. . . ", "identical_positions": 55, "similar_positions": 66, "identity": "9.2%" }, { "cls_id": "homologset.agr.FB:FBgn0004102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63410-1", "uniprot_id": "OTX1_RAT", "id": "Q63410-1", "name": "Homeobox protein OTX1", "aln": "-MMSYLKQ----------------------------PPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ--------SGNGTKSRPVKKKS--SPVRESSG-SESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPASVSVPEPLGAPSNASCMQRSVAAGA-ATAATSYPMSYGQGRSYGQG-------------------------------------------------YPAP-SSSYFGG---------------------------------------------------------------VDCSSYLAPM-------HSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHH----HHHHHHHHQGYGG---------SGLAFNS-ADCLDYKEPAAAAASSAWKLNFN------------SPDCLDYKDQAS-WRFQVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P80205-1", "uniprot_id": "OTX1_MOUSE", "id": "P80205-1", "name": "Homeobox protein OTX1", "aln": "-MMSYLKQ----------------------------PPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ--------SGNGTKTRPVKKKS--SPVRESSG-SESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPTSVSVPEPLAAPSNASCMQRSVAAGA-ATAAASYPMSYGQGGSYGQG-------------------------------------------------YPAP-SSSYFGG---------------------------------------------------------------VDCSSYLAPM-------HSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHH----HHHHHHHHQGYGG---------SGLAFNS-ADCLDYKEPAAAAASSAWKLNFN------------SPDCLDYKDQAS-WRFQVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32242-1", "uniprot_id": "OTX1_HUMAN", "id": "P32242-1", "name": "Homeobox protein OTX1", "aln": "-MMSYLKQ----------------------------PPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ--------SGSGTKSRPAKKKS--SPVRESSG-SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGA-ATAAASYPMSYGQGGSYGQG-------------------------------------------------YPTP-SSSYFGG---------------------------------------------------------------VDCSSYLAPM-------HSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSG-HH----HHHHHHHHQGYGG---------SGLAFNS-ADCLDYKEPGAAAASSAWKLNFN------------SPDCLDYKDQAS-WRFQVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91994-1", "uniprot_id": "OTX1B_DANRE", "id": "Q91994-1", "name": "Homeobox protein OTX1 B", "aln": "-MMSYLKQ----------------------------PPYAMNGLGLSGAAMDLLHPSVGYPATPRKQRRERTTFTRSQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ--------SGSSTKTRPAKKKS--SPTRESTG-SESSGQFTPPAVSSAGSSSSSSSSTNN-------TGIS------STSTSISTVSSIWSPA-ISPGSAPPSVSLPEP-VAPSNTSCMQRSVSG----TASSTYPMPYNQTTGYSQG-------------------------------------------------YPTP-SGSYFSG---------------------------------------------------------------VDCGSYLAPM-------HSHHHPHQLSPMTASSMPTHPHHH------ISQSSG--------HHHHHHHQAYSG---------TGLAFNS-SDCLDYKEQ----TASSWKLNFN------------TTDCLDYKDQAS-WRFQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90267-1", "uniprot_id": "OTX1A_DANRE", "id": "Q90267-1", "name": "Homeobox protein OTX1 A", "aln": "-MMSYLKQ----------------------------APYAMNGLGLGGATMDLLHPSVGYPTNPRKQRRERTTFTRTQLDILESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQ-------SSTNSKIRPAKKKP--SPSRESPG-SESSGHFTPPAVSSSSSSSSSSSGSNP----SALSGVG----LISSSSSGTPVPSIWSPAPVSPVPAPPSLPDISP---PASASCMQRAMSSGGGTTGVPSYPMPYNQAPSYAQG-------------------------------------------------YPTSNAASYFGG---------------------------------------------------------------MDCGSYLAPMT-----GHAHHHPHAHHSQLSTAAAVSGHHHP---HHIGQSSG----------HHPHHQGYGG---------TALPFSS-SDCLDYKEQ----VASSWKLNFSS----------AAADCLDYKDQAA-WRFQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32243-1", "uniprot_id": "OTX2_HUMAN", "id": "P32243-1", "name": "Homeobox protein OTX2", "aln": "-MMSYLKQ----------------------------PPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ-----NGGQNKVRPAKKKT--SPAREVSSESGTSGQFTPPSSTSVPTIASSS-----------------------------APVSIWSPASISPLSDPLST----------SSSCMQR------------SYPMTYTQASGYSQG-------------------------------------------------YAGS--TSYFGG---------------------------------------------------------------MDCGSYLTPMH-----HQLPGPGATLSPMGTNAVTSH----------LNQSPA-----------SLSTQGYGA---------SSLGFNSTTDCLDYKDQ-----TASWKLNFN-------------ADCLDYKDQTSSWKFQVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80206-1", "uniprot_id": "OTX2_MOUSE", "id": "P80206-1", "name": "Homeobox protein OTX2", "aln": "-MMSYLKQ----------------------------PPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ-----NGGQNKVRPAKKKS--SPAREVSSESGTSGQFTPPSSTSVPTIASSS-----------------------------APVSIWSPASISPLSDPLST----------SSSCMQR------------SYPMTYTQASGYSQG-------------------------------------------------YAGS--TSYFGG---------------------------------------------------------------MDCGSYLTPMH-----HQLPGPGATLSPMGTNAVTSH----------LNQSPA-----------SLSTQGYGA---------SSLGFNSTTDCLDYKDQ-----TASWKLNFN-------------ADCLDYKDQTSSWKFQVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91981-1", "uniprot_id": "OTX2_DANRE", "id": "Q91981-1", "name": "Homeobox protein OTX2", "aln": "-MMSYLKQ----------------------------PPYTVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ-----NGGQNKVRPAKKKS--SPAREASSESGASGQFTPPSSTSVPAISTTT-----------------------------APVSIWSPASISPLSDPLST----------SSSCMQR------------SYPMTYTQASGYSQG-------------------------------------------------YAGS--TSYFGG---------------------------------------------------------------MDCGSYLTPMH-----HQLTGPGSTLSPMSSNAVTSH----------LNQSPA-----------SLPTQGYGA---------SGLGFNSTADCLDYKDQ-----ASSWKLNFN-------------ADCLDYKDQTSSWKFQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8JIZ3-1", "uniprot_id": "Q8JIZ3_DANRE", "id": "Q8JIZ3-1", "name": "", "aln": "-MMSYIKQ----------------------------PHYAVNGLTLSASGMDLLHTAVGYPATPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQ-------TSGQPKPRPPKKKS--SPPPDLTSDPGTSSSVVAAPTPTVPPSVSAG----------------------------TAPVSVWSPTSLSPLPDPLCG---------SGTPCVQRP----------APYPMSYGQPSSYSQG-------------------------------------------------YGSS---PYFSG---------------------------------------------------------------LDCSPYLSPMT-----TQLSASGGALSPLTVPSMGGS----------LSQSPS------------LSSQGYST---------ASLGFSS-VDCLDYKDQ------QAWKLNFS------------TVDCLDHK-------FQVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WTQ9-1", "uniprot_id": "Q9WTQ9_RAT", "id": "Q9WTQ9-1", "name": "Cone-rod homeobox protein", "aln": "-MMTYMNPG---------------------------PHYSVNALALSGPSVDLMHQAVPYSSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGVQAKARPAKRKAG-TSPRPSTDVCTDPLGISDSYSPSLPGPSGSP-------------------------TTAVATVSIWSPASESPLPEAQRAG------LVASGSSLTS-----------APYAMTYAPASAFCSSPS----------------------------------------------AYASP--SSYFSG---------------------------------------------------------------LDP--YLSPMV-----PQLGGP--ALSPLSGPSVGPS----------LAQSPT-----------SLSGQSYS-------------TYSP-VDSLEFKDP-----TGTWKFTYN------------PMDPLDYKDQSA-WKFQIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54751-1", "uniprot_id": "CRX_MOUSE", "id": "O54751-1", "name": "Cone-rod homeobox protein", "aln": "-MMAYMNPG---------------------------PHYSVNALALSGPNVDLMHQAVPYSSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAG-TSPRPSTDVCTDPLGISDSYSPSLPGPSGSP-------------------------TTAVATVSIWSPASEAPLPEAQRAG------LVASGPSLTS-----------APYAMTYAPASAFCSSPS----------------------------------------------AYASP--SSYFSG---------------------------------------------------------------LDP--YLSPMV-----PQLGGP--ALSPLSGPSVGPS----------LAQSPT-----------SLSGQSYS-------------TYSP-VDSLEFKDP-----TGTWKFTYN------------PMDPLDYKDQSA-WKFQIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43186-1", "uniprot_id": "CRX_HUMAN", "id": "O43186-1", "name": "Cone-rod homeobox protein", "aln": "-MMAYMNPG---------------------------PHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAG-TSPRPSTDVCPDPLGISDSYSPPLPGPSGSP-------------------------TTAVATVSIWSPASESPLPEAQRAG------LVASGPSLTS-----------APYAMTYAPASAFCSSPS----------------------------------------------AYGSP--SSYFSG---------------------------------------------------------------LDP--YLSPMV-----PQLGGP--ALSPLSGPSVGPS----------LAQSPT-----------SLSGQSYG-------------AYSP-VDSLEFKDP-----TGTWKFTYN------------PMDPLDYKDQSA-WKFQIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22810-1", "uniprot_id": "HMOC_DROME", "id": "P22810-1", "name": "Homeotic protein ocelliless", "aln": "MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLNLGVGVGVGVGVGVGVSQDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPMSPQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYYSQMEYFSNQNQVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDYMSPQDKYANMV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . :. : * : . : .************:**: **:** **:***:: ***************************** * . . :. :. . . . * :.. : . . . . . . . * . .* :: ::** . : :*. * * : . : :::: : :. . : **: : ", "identical_positions": 64, "similar_positions": 61, "identity": "11.79%" }, { "cls_id": "homologset.agr.FB:FBgn0004103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62138-1", "uniprot_id": "PP1A_RAT", "id": "P62138-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62137-1", "uniprot_id": "PP1A_MOUSE", "id": "P62137-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62136-1", "uniprot_id": "PP1A_HUMAN", "id": "P62136-1", "name": "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "aln": "MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR--NSAKAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12982-1", "uniprot_id": "PP12_DROME", "id": "P12982-1", "name": "Serine/threonine-protein phosphatase alpha-2 isoform", "aln": "MGD--VMNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRKK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P63087-1", "uniprot_id": "PP1G_MOUSE", "id": "P63087-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRGMITKQAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63088-1", "uniprot_id": "PP1G_RAT", "id": "P63088-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRGMITKQAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36873-1", "uniprot_id": "PP1G_HUMAN", "id": "P36873-1", "name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "aln": "MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN---------ATRPVTPPRGMITKQAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32598-1", "uniprot_id": "PP12_YEAST", "id": "P32598-1", "name": "Serine/threonine-protein phosphatase PP1-2", "aln": "-MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLNSMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQKSLPR-------------------QAGGRKKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::*.** *****:*::**::*:* *.*** ** *:*.**:.**********:*****************************************************:*.****:************************.***************:***:****** ******** *******:*****:** ************** **.***********.:** :**:*::::****************:** ************************::*:*********:* ", "identical_positions": 247, "similar_positions": 38, "identity": "74.4%" }, { "cls_id": "homologset.agr.FB:FBgn0004106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11440-1", "uniprot_id": "CDK1_MOUSE", "id": "P11440-1", "name": "Cyclin-dependent kinase 1", "aln": "----MEDYIKIEKIGEGTYGVVYKGRHRVTGQ---IVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS-RLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39951-1", "uniprot_id": "CDK1_RAT", "id": "P39951-1", "name": "Cyclin-dependent kinase 1", "aln": "----MEDYIKIEKIGEGTYGVVYKGRHRTTGQ---IVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS-RLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06493-1", "uniprot_id": "CDK1_HUMAN", "id": "P06493-1", "name": "Cyclin-dependent kinase 1", "aln": "----MEDYTKIEKIGEGTYGVVYKGRHKTTGQ---VVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS-RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23572-1", "uniprot_id": "CDK1_DROME", "id": "P23572-1", "name": "Cyclin-dependent kinase 1", "aln": "----MEDFEKIEKIGEGTYGVVYKGRNRLTGQ---IVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEEN-RIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00546-1", "uniprot_id": "CDK1_YEAST", "id": "P00546-1", "name": "Cyclin-dependent kinase 1", "aln": "MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ::**:**********. . .** :**:*******::*****************:. *** * *:: .: ::**:****.:***:*::.:* .: : :.:*:.:: *: ..* :** :*:************:..* :*:.****.*:**:*:* ****:******:******. :** ** **** ****:..:**:* *******:*::** * **.: :** : * *:* :** * .*:. : .** .*:**:.*:* *** :***.: ****: ", "identical_positions": 155, "similar_positions": 87, "identity": "50.82%" }, { "cls_id": "homologset.agr.FB:FBgn0004107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80YP0-1", "uniprot_id": "CDK3_MOUSE", "id": "Q80YP0-1", "name": "Cyclin-dependent kinase 3", "aln": "----MDVFQKVEKIGEGTYGVVYKARNKVTG---QLVALKKIRLDLEAEGVPSTAVREISLLKELKHPNIIKLLDVVHRE-KKLYMVFEFLTQDLKRHMDSSPTSE-LPLPVVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLDGLGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYSTAVDIWSIGCIFAEM------------------------------------------------VTGKALFPGDSEIDQLFRIFRTLGTPSEATWPGVSQMPDYQSSFPKWSRKGLEEIVPSLGPEGKDLLLRLLQYDPSQRISAKTALAHPYFS-PGHSLAPQQCTAGRSSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00526-1", "uniprot_id": "CDK3_HUMAN", "id": "Q00526-1", "name": "Cyclin-dependent kinase 3", "aln": "----MDMFQKVEKIGEGTYGVVYKAKNRETG---QLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNE-RKLYLVFEFLSQDLKKYMDSTPGSE-LPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEM------------------------------------------------VTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFRH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97377-1", "uniprot_id": "CDK2_MOUSE", "id": "P97377-1", "name": "Cyclin-dependent kinase 2", "aln": "----MENFQKVEKIGEGTYGVVYKAKNKLTG---EVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-NKLYLVFEFLHQDLKKFMDASALTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSAPHPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63699-1", "uniprot_id": "CDK2_RAT", "id": "Q63699-1", "name": "Cyclin-dependent kinase 2", "aln": "----MENFQKVEKIGEGTYGVVYKAKNKLTG---EVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-NKLYLVFEFLHQDLKKFMDASALTG-LPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM------------------------------------------------VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24941-1", "uniprot_id": "CDK2_HUMAN", "id": "P24941-1", "name": "Cyclin-dependent kinase 2", "aln": "----MENFQKVEKIGEGTYGVVYKARNKLTG---EVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-NKLYLVFEFLHQDLKKFMDASALTG-IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM------------------------------------------------VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00546-1", "uniprot_id": "CDK1_YEAST", "id": "P00546-1", "name": "Cyclin-dependent kinase 1", "aln": "MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEM------------------------------------------------CNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23573-1", "uniprot_id": "CDK2_DROME", "id": "P23573-1", "name": "Cyclin-dependent kinase 2", "aln": "MTTILDNFQRAEKIGEGTYGIVYKARSNSTG---QDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISG-NNLYMIFEYLNMDLKKLMDK--KKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM------------------------------------------------IMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPIT--EHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPNAGSASRLTRLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: **:******:**** . .* . ********: * *******:*******:*:. *:::* *:: .:**::**:* ***: *: : ::*.:: *: ..:.:**::*::**********:: * :**.********.**:*:****:*********:*** * *:*.** **:****:** :.:*.*******:::*** *.**.* **.: :**:: .**:* .: : :. . .*: :* *** **:*: * *.:* ", "identical_positions": 140, "similar_positions": 84, "identity": "37.84%" }, { "cls_id": "homologset.agr.FB:FBgn0004110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95096-1", "uniprot_id": "NKX22_HUMAN", "id": "O95096-1", "name": "Homeobox protein Nkx-2.2", "aln": "----------------------------MSLTNTKTGFSVKDILDLPDTNDEEG----------------------SVAEGPEEENEGPE------PAKRAGPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAG-APPQDSSSKSPEPSADESPDNDK------------------ETPGGGGDAGKKRKRRVLFSKAQTYELER-------RFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMK------RARAEKGMEVTPLPS-------P---RRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHM-----------------QYNAQYSSAS-----------TPQYPTAHPLVQAQQWTW-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A7B5-1", "uniprot_id": "D4A7B5_RAT", "id": "D4A7B5-1", "name": "", "aln": "-----------------------------MASSGRLGFTVRSLLNLPEQD--------------------------------------AQ------PRVRC--------EQQTCVPQTAAWLESERSHYP---SSDE------SGLET---SPADSS---------QLASLGR------------------ASPGS--DAEKRRKRRVLFSKAQTLELER-------RFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLK------RGRAPGVTESSDVTASADLHAAPGLLRRVVVPVLVHDRSPCNG-RGEGTAAVPQDKCSSRLATACPVQGYT-----------------AFGPGSALGL-----------FPAYQHLAPPALVS-WNW-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97334-1", "uniprot_id": "NKX23_MOUSE", "id": "P97334-1", "name": "Homeobox protein Nkx-2.3", "aln": "-------------------------MMLPS-PVTSTPFSVKDILNLEQ-QRHFH----------------------GAHLQAELEQHFHS-APCMLATAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHGDSGLCPQSYVHTVLRDACSGPKEQEEEVVSERSQKSCQLKKSL--------EAAGDCKTSEDGERPKPRSRRKPRVLFSQAQVFELER-------RFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCK------RQRQDKSLELGTHAPPPPP-------RRVAVPVLVRDGKPCVTPSAQTYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGTASAATTAMQPACSATGGGSFVNVSNLGGFGSGGGAQPLHQGAAAGSACTQGTLQGIRAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZC9-1", "uniprot_id": "D3ZZC9_RAT", "id": "D3ZZC9-1", "name": "", "aln": "-------------------------MMIPS-PVTSTPFSVKDILNLEQ-QRHFH----------------------GAHLQAELEQHLHS-APCMLAAAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHGVSGLCPQSYVHTVLRDSCSGPKEQEEEVVSERSQKSCQLKKSL--------EAAGDCKASEDGERPKPRSRRKPRVLFSQAQVFELER-------RFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCK------RQRQDKSLELGTHAPPPPP-------RRVAVPVLVRDGKPCVTPSAQAYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGAASAATTAMQPACSATGGGSFVNVGNLGGFGSGGGAQPLHQGAAAGAACAQGTLQGIRAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35767-1", "uniprot_id": "NKX25_RAT", "id": "O35767-1", "name": "Homeobox protein Nkx-2.5", "aln": "--------------------------MFPSPALTHTPFSVKDILNLEQQQRSLA----------------------AGDLSARLEATLAP-ASCMLAAFKPDGYSGPEAAAPGLAE-LRAELGPAPSPPKCSPAFPTAPTFYPRAYGD----PDPAKDPRADK--KELCALQK----------AVELDKAETDGAERRRPRRRRKPRVLFSQAQVYELER-------RFKQQRYLSPAERDQLASVLKLTSTQVKIWFQNRRYKCK------RQRQDQTLEL-LGPPPPPA-------RRIAVPVLVRDGKPCLG-DSAAYAPAYGLGLNAYGYNAYPYPGYG---------------GAACSPAYSCAA-----------YPAAPPAAHAPAASANS-NFVNFG-VGDLNTVQSPGMPQGNSGVS------TLHGIRAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42582-1", "uniprot_id": "NKX25_MOUSE", "id": "P42582-1", "name": "Homeobox protein Nkx-2.5", "aln": "--------------------------MFPSPALTPTPFSVKDILNLEQQQRSLA----------------------SGDLSARLEATLAP-ASCMLAAFKPEAYSGPEAAASGLAE-LRAEMGPAPSPPKCSPAFPAAPTFYPGAYGD----PDPAKDPRADK--KELCALQK----------AVELDKAETDGAERPRARRRRKPRVLFSQAQVYELER-------RFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCK------RQRQDQTLEL-LGPPPPPA-------RRIAVPVLVRDGKPCLG-DPAAYAPAYGVGLNAYGYNAYPYPSYG---------------GAACSPGYSCAA-----------YPAAPPAAQPPAASANS-NFVNFG-VGDLNTVQSPGMPQGNSGVS------TLHGIRAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7UZK3-1", "uniprot_id": "A0A8N7UZK3_DANRE", "id": "A0A8N7UZK3-1", "name": "Homeobox protein Nkx-2.5", "aln": "------------------------MAMFSS-QMTSTPFSVRDILNLEQNQEDMV----------------------SLDMSQRLDSALIPTSSCMLSTFKQEQFMEMPSGSSLFSEDLQEDKGNKINSINFSASGFYAKNFLEMDYVK----DAKTDDTFEDKEKKDIGCCQE----------DPGED-LKLDDAERPKQRKRRKPRVLFSQAQVYELER-------RFKQQKYLSAPERDHLANVLKLTSTQVKIWFQNRRYKCK------RQRQDQTLEM-VGIAPP---------RRISVPVLVRDGKPCLG-DTSTYNTSYNVGINHFTYNTYPAFSNF---------------PSPGNSNYSCN------------YPSSMSSIQP--SQSNS-NYMNFG-VGDLNNVQAS---FQSSSVP------SLHGIRAW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43688-1", "uniprot_id": "NKX26_MOUSE", "id": "P43688-1", "name": "Homeobox protein Nkx-2.6", "aln": "--------------------------MLSS-PVASTPFSVADILRLECQQKDSK----------------------TLSQWELHRNPVKP------RYLRMNQESGWFESSD--RAQAVPFRCTWETVLEMGSNPVGEPQTPPGTISR-----LGARNPMTDRGVGNLSGDMR------------------RGGPVSTRTRPQRKSRVLFSQAQVLALER-------RFKQQRYLTAPEREHLASALQLTSTQVKIWFQNRRYKSK------SQRQDQTLELAGHPLAP---------RRVAVPVLVLDGKPCLDPDVAAFLGPYKATSPYSCFGGYAGTPYD----------------ASYASRCTSA-------------SAGPGPLTPLASSGFS------------PGGQSAAPQGHLPATP--------QGVTAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EZF0-1", "uniprot_id": "F7EZF0_RAT", "id": "F7EZF0-1", "name": "", "aln": "--------------------------MLRS-PVASTPFSVEDILRLEYWQKDSK----------------------TMSQWELHRNTVKP------QYIRMNPESGRSESFDTVQTEATPFLCTWETVLEMDSNLVREPKTPPGTISP-----LGVENLMMEHGVGNRSDDPR------------------RAGPVPTVTRPRRKPRVLFSQAQVLALER-------RFKQQRYLSAPEREHLASVLQLTSTQVKIWFQNRRYKCK------RQRQDQTLELAGHPLAP---------RRVAVPVLVLDVKPCLDPDRHAFPSPYATTVLYSCFSSYTGTPYS----------------ASYAGRYT---------------GAGPGPLAPLASSGFS------------PGGQSAAPQGHLAATP--------QGVTA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22711-1", "uniprot_id": "TIN_DROME", "id": "P22711-1", "name": "Muscle-specific homeobox protein tinman", "aln": "MLQHHQQQAQSGGYYDHYTQSPSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAATASALFAAGEYQNPHQYLNHQQHQQSELPIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNR-----RYKSKRGDIDCEG-----------IAKHLKLKSEPLDSPTSLPPPIPNHVMWPPTMQQSQQQQQHHAQQ--------QQMQHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* .:* : . . .: : . *: : *: . ::* :.: .*: .:. * * * : * * :: . ", "identical_positions": 12, "similar_positions": 28, "identity": "2.73%" }, { "cls_id": "homologset.agr.FB:FBgn0004117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63610-1", "uniprot_id": "TPM3_RAT", "id": "Q63610-1", "name": "Tropomyosin alpha-3 chain", "aln": "MAGSTTIEAVKRKIQVLQQQADDAEERAER---------------------------------------------------------------LQREVEGERRAREQ---------------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z2H9-1", "uniprot_id": "D3Z2H9_MOUSE", "id": "D3Z2H9-1", "name": "", "aln": "MAGTTTIEAVKRKIQVLQQQADDAEERAER---------------------------------------------------------------LQQEVEGERRARKQ---------------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IRU2-1", "uniprot_id": "TPM4_MOUSE", "id": "Q6IRU2-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADDAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESERGMKVIENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09495-1", "uniprot_id": "TPM4_RAT", "id": "P09495-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADDAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDAAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKSSDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67936-1", "uniprot_id": "TPM4_HUMAN", "id": "P67936-1", "name": "Tropomyosin alpha-4 chain", "aln": "MAGLNSLEAVKRKIQALQQQADEAEDRAQG---------------------------------------------------------------LQRELDGERERREK---------------------AEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58771-1", "uniprot_id": "TPM1_MOUSE", "id": "P58771-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELV------------------------------------------SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04692-1", "uniprot_id": "TPM1_RAT", "id": "P04692-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELV------------------------------------------SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09493-1", "uniprot_id": "TPM1_HUMAN", "id": "P09493-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELV------------------------------------------SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13104-1", "uniprot_id": "TPM1_DANRE", "id": "P13104-1", "name": "Tropomyosin alpha-1 chain", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAETDKKAAEERSKQLEDDLV------------------------------------------ALQKKLKATEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNEGKCSELEEELKTVTNNMKSLEAQAEKYSAKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06753-1", "uniprot_id": "TPM3_HUMAN", "id": "P06753-1", "name": "Tropomyosin alpha-3 chain", "aln": "-----MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELA------------------------------------------AMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21107-1", "uniprot_id": "TPM3_MOUSE", "id": "P21107-1", "name": "Tropomyosin alpha-3 chain", "aln": "-----MMEAIKKKMQMLKLDKENVLDRAEQAEAEQKQAEERSKQLEDELA------------------------------------------TMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISDELDHALNDMTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58774-1", "uniprot_id": "TPM2_MOUSE", "id": "P58774-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQ------------------------------------------ALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58775-1", "uniprot_id": "TPM2_RAT", "id": "P58775-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQ------------------------------------------ALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07951-1", "uniprot_id": "TPM2_HUMAN", "id": "P07951-1", "name": "Tropomyosin beta chain", "aln": "------MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQ------------------------------------------ALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TFB7-1", "uniprot_id": "A0AB32TFB7_DANRE", "id": "A0AB32TFB7-1", "name": "", "aln": "------MDAIKKKMQMLKLDKENALDRAEQAEGDKKAAEDRSKQLEDELIQLEKRLRVTEDERDKVLEEYQSVEEKLLTAEEVATKLEDDLLALQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEGDVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMEIQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELNERCNRRLQDELRVLDQTYKSLKASEEQYSQKEDKYEEEIKVLTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYSQKLKYKAISEELDHALNDMTSM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8Q650-1", "uniprot_id": "A0A2R8Q650_DANRE", "id": "A0A2R8Q650-1", "name": "", "aln": "------MEAVKKKMMMLKLDKENALDQAEQAETDRKAAEERSKQHEDELI------------------------------------------QMQKKLKGTEDELDKYSEALKDAQEKLEISEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIVEGELERTEERAELAESHVKQMEEELRALDQTLKTLQASEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEEKLRDAKEENIKIHATLDQTLSELNSF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1R412-1", "uniprot_id": "F1R412_DANRE", "id": "F1R412-1", "name": "", "aln": "------MEAIKKKMQMLKLDKENAIDRAEQAETEQKAAEDKCKQLDDELV------------------------------------------GLQKKLKQTEDELDKYSEALKDAQEKLELSEKKAADAEGDVAALNRRIQLVEEELDRAQERLGTALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVAECKASDLEEELKNVTNNLKSLEAQAEKYSEKEDKYEEEIKVLSDKLKEAETRAEFAERTVAKLEKSIDDLEEKLSSAKEENLGMHQVLDQTLQELNSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09491-1", "uniprot_id": "TPM2_DROME", "id": "P09491-1", "name": "Tropomyosin-2", "aln": "------MDAIKKKMQAMKLEKDNAIDKADTCENQAKDANSRADKLNEEVR------------------------------------------DLEKKFVQVEIDLVTAKEQLEKANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQSADENNRMCKVLENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEEELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQKEVDRLEDRLFNEKEKYKAICDDLDQTFAELTGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:*:*: :: : ::. ::*: ::::. . :*.:.*: **::* :**:*::::*: ** *:* ** ::***.:* **:*.*: :***:*: *****: :::::* * :**:***.::*.:*: :*:*.. * :::::: : :. * *.. :: . : :.::.*:* * ****** ***.**: * :*:* :* **:.: * : **::: ::. ", "identical_positions": 73, "similar_positions": 99, "identity": "21.99%" }, { "cls_id": "homologset.agr.FB:FBgn0004118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43143-1", "uniprot_id": "ACHA6_RAT", "id": "P43143-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "------------------------------------------MLNGWGR--GDLRSGLCLWICG----------------------FLAFFKGSRGCVSEEQLFHTLFAHYNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTE----YDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK---------VDMNDFWENSEWEIVDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHT-MPKWVKTMFLQVFPSILMMRRP------LDKTKEMDGVKDPK--THTKRP------------AKVKFTHR------KEPKLLKECRHCHKSSEIAPGKRLS-QQPAQWVTENSE----HPPDVEDVIDSVQFIAENMKSHNETKEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQ------------------PLLGNTGAS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0W9-1", "uniprot_id": "ACHA6_MOUSE", "id": "Q9R0W9-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "------------------------------------------MLNSRDQ--GNLHSGLCLWLCG----------------------FLALFKGSTGCESEEQLFHRLFAHYNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTE----YDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK---------VDMNDFWENSEWEIVDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHT-MPKWVKTIFLQAFPSILMMRKP------LDKTKEAGGVKDPK--SHTKRP------------AKVKFTHR------GESKLLKECHHCQKSSDIAPGKRRSSQQPARWVAENSE----HSSDVEDVIESVQFIAENMKSHNETNEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQ------------------PLLGNTGKS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15825-1", "uniprot_id": "ACHA6_HUMAN", "id": "Q15825-1", "name": "Neuronal acetylcholine receptor subunit alpha-6", "aln": "------------------------------------------MLTSKGQ--GFLHGGLCLWLCV----------------------FTPFFKGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPME----YDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK---------VDMNDFWENSEWEIIDASG---YKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHT-MPRWVKTVFLKLLPQVLLMRWP------LDKTRGTGSDAVPR--GLARRP------------AKGKLASH------GEPRHLKECFHCHKSNELATSKRRLSHQPLQWVVENSE----HSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQ------------------PLLGNTGKS-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04757-1", "uniprot_id": "ACHA3_RAT", "id": "P04757-1", "name": "Neuronal acetylcholine receptor subunit alpha-3", "aln": "---------------------------------------MGVVLL------PPPLSMLMLVL--------------------------MLLPAASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSD----YQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS---------MNLKDYWESGEWAIIKAPG---YKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT-MPTWVKAVFLNLLPRVMFMTRPTSGEGDTPKTRTFYGAELSNLNCFSRAD---------SKSCKEGYPCQ------DGTCGYCHHRRVKISNFSANLTRSSSSESVNAVLSLSA----LSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQ------------------PLMARDDT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4G9-1", "uniprot_id": "ACHA3_MOUSE", "id": "Q8R4G9-1", "name": "Neuronal acetylcholine receptor subunit alpha-3", "aln": "---------------------------------------MGVVLP------PPPLSMLMLVL--------------------------MLLPVASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSD----YQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSS---------MNLKDYWESGEWAIIKAPG---YKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT-MPTWVKAVFLNLLPRVMFMTRPTSTEEDAPKTRNFYGAELSNLNCFSRAD---------SKSCKEGYPCQ------DGTCGYCHHRRVKISNFSANLTRSSSSESVDAVLSLSA----LSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQ------------------PLMARDDT--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HV46-1", "uniprot_id": "A0AC58HV46_DANRE", "id": "A0AC58HV46-1", "name": "", "aln": "---MRSLSDQYLHWKQDENSCIFCSLSLTHTYMRTHTHTLSLSLSSSSSPGPPLVCTAALFLSPDCTMNTGALLIFFS----SFSPLCFLLSGVCCSEAEHRLFSVIFSSYNQYIRPVENVSDPVVVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKD----FGGVEFIRVPSNKIWKPDIVLYNNAVGDFQVDDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGST---------INLKDFWESGEWTIIDAPG---YKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCG-EKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHT-MPCWVRRVFLSLLPRVMFMTRPEKDQEVPAKQCSVHPPVSSKQTSVCRGPQLLLCPTELNEASRTAFLCR------EHHCWKKHISNMTSEGAEDGGSPCSSSESLDGFLCMSA----VSPQVREAIESVKYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQ------------------PLLLGEDM--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P12389-1", "uniprot_id": "ACHA2_RAT", "id": "P12389-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-----------------------------------------MTLSHSALQFWTHLYLWCLLLVPA-----------------------VLTQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNVTSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERT---------VDLKDYWESGEWAIINATG---TYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRPLPPMELHGSPDLKLSPSYHWLETNMDAG------------EREETEEEEEEE-DENICVCAGLPDSSMGVLYGHGGLHLRAMEPETKTPSQASEILLSPQIQKALEGVHYIADRLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLP------------------PFLAGMI---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X60-1", "uniprot_id": "ACHA2_MOUSE", "id": "Q91X60-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-----------------------------------------MAPSHPAFQFWIHLYLWCLLLMPA-----------------------VLAQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAE----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMERT---------VDLKDYWESGEWAIINATG---TYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHN-MPNWVRVALLGRVPRWLMMNRPLPPMELHGSPGLKLSPTYHWLETNMDAE------------EREETEEEEEEEEDENICMCAGLPDSSMGVLYGHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFLP------------------PFLAGMI---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15822-1", "uniprot_id": "ACHA2_HUMAN", "id": "Q15822-1", "name": "Neuronal acetylcholine receptor subunit alpha-2", "aln": "-----------------------------------------MGPSCPVFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDRLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTD----FGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQT---------VDLKDYWESGEWAIVNATG---TYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCG-EKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHT-MPHWVRGALLGCVPRWLLMNRPPPPVELCHPLRLKLSPSYHWLESNVDAE------------EREVVVEE------EDRWACAGHVAPSVGTLCSHGHLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLP------------------PFLAGMI---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12391-1", "uniprot_id": "ACHB3_RAT", "id": "P12391-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "---------------------------------------------------MTGFLRVFLVLS--------------ATLSGSWVTLTATAGLSSVAEHEDALLRHLFQGYQKWVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEE----YGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN---------VDRKDFFDNGEWEILNAKG---MKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQRLPRWLCMKDP---------MDRFSFPDGKESDTAVRGK----------------------------------VSGKRKQTPASDGERVL------------------VAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIASVLGSILIFIP------------------ALKMWIHRFH------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMN3-1", "uniprot_id": "ACHB3_MOUSE", "id": "Q8BMN3-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "---------------------------------------------------MTGFLRVFLALS--------------ATLSGSWVTLTATAGLSSVAEHEDALLRHLFQGYQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPED----YGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTYDGTMVDLILINEN---------VDRKDFFDNGEWEILNAKG---MKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCMKDP---------RDRFSFPDGTESKGTVRGK----------------------------------FPGKKKQTPTSDGERVL------------------VAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTASVLGSVLIFIP------------------ALKMWIHRFH------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05901-1", "uniprot_id": "ACHB3_HUMAN", "id": "Q05901-1", "name": "Neuronal acetylcholine receptor subunit beta-3", "aln": "--------------------------------------------------MLPDFMLVLIVLG--------------IPSS-------ATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDD----YGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINEN---------VDRKDFFDNGEWEILNAKG---MKGNRRDGVYS--YPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG-EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMKDH---------VDRYSSPEKEESQPVVKGK----------------------------------VLEKKKQKQLSDGEKVL------------------VAFLEKAADSIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIVSVTGSVLIFTP------------------ALKMWLHSYH------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20420-1", "uniprot_id": "ACHA5_RAT", "id": "P20420-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "--------------------------------------------------------MVQLLAGRW------------RPTGARRGTRGGLPELSSAAKHEDSLFRDLFEDYERWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD---------VDRTDFFDNGEWEIMSAMG---SKGNRTDSCCW--YPYITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSH---------ADRYFT--------------------------------------------------QREEAESGAGPKS-------------------RNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVP------------------VIYKWANIIVPVHIGNTIK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2MKA5-1", "uniprot_id": "ACHA5_MOUSE", "id": "Q2MKA5-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "-----------------------------------------MAARGSRRRALRLLLMVQLLAGRW------------RPAGAARGARGGLPELSSAAKHEDSLFRDLFEDYEKWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKIIRVPSDSLWIPDIVLFDNADGRFEG-ASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD---------VDRTDFFDNGEWEIMSAMG---SKGNRTDSCCW--YPCITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEG-EKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSH---------ADRYFT--------------------------------------------------QREEAEKDGGPKS-------------------RNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVP------------------VIYKWANIIVPVHIGNTIK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30532-1", "uniprot_id": "ACHA5_HUMAN", "id": "P30532-1", "name": "Neuronal acetylcholine receptor subunit alpha-5", "aln": "-----------------------------------------MAARGSGPRALRLLLLVQLVAGRC------------GLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDD----YGGIKVIRVPSDSVWTPDIVLFDNADGRFEG-TSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQD---------VDKRDFFDNGEWEIVSATG---SKGNRTDSCCW--YPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEG-EKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMRSH---------VDRYFT--------------------------------------------------QKEETESGSGPKSS------------------RNTLEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVP------------------VIYKWANILIPVHIGNANK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25162-1", "uniprot_id": "ACH4_DROME", "id": "P25162-1", "name": "Acetylcholine receptor subunit beta-like 2", "aln": "------------------------------------------------MWHWSLLCVFLLVPLAN----------------------STAPISFEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEE----YGGVEQLYVPSEHIWVPDIVLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLVQVGIDLTEFYLSVEWDILEVPA---TKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSG-EKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHN-MSPLVRKLFLHFMPKLMMMRRT-----QYTLPDYDDSTPSNGYTNEIDVR--------------------------DSISDFPSEFKDSQDGAYDNGMQNSVDSDNVIPRN-------LTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPIDRQLSEIPLRKNNFMLPPDIVRQVLT---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F9V1-1", "uniprot_id": "E7F9V1_DANRE", "id": "E7F9V1-1", "name": "", "aln": "MDQ--------------------------------------NLSSKIIWLWILLFRFS----------------------------------GALC-NLEGSLHRDLMVGYNKNIRPVESHEDIIDVKIKMTLTNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLENNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLS-DEDNVTMEWIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELE--HQEIIFFLIIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPETSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHP-MSNTIRKVLLNILPRVLRMTMQRWTPEQEEGDFKMFALGNGTPLRRRRRSS----------LGLIAKADEYMFRTARSELMFSRL-KERKGLLKNTLEKIQNGLGGNTAQDLECSLAAASPEVQQCVSSCKHIAESTKHQNDFQSKNEEWFLVARVIDRMCFFVMALLFILGTIGIFLTG-----------------HFNQAPSQPFPGDPKKYLPEISAGDIPG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20782-1", "uniprot_id": "ACHE_MOUSE", "id": "P20782-1", "name": "Acetylcholine receptor subunit epsilon", "aln": "------------------------------------------MAGALLGALLLLTLFG----------------------------------RSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIDWHDYRLNYSKDD----FAGVGILRVPSEHVWLPEIVLENNIDGQFGVAYDSNVLVYEGGYVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFIFAVDDDGNTINKIDIDTAAFTENGEWAIDYCPGMIRRYEGGSTEGPG--ETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHA-TSPRLRQILLELLPRLLGS-----SPPPED---------PRTASPARRASS----------VGILLRAEELILKKPRSELVFEGQ-RHRHGTWTAALC--QN-------------LGAAAPEIRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGG-----------------YFNQVPDLPYP-------PCIQP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09690-1", "uniprot_id": "ACHB_MOUSE", "id": "P09690-1", "name": "Acetylcholine receptor subunit beta", "aln": "--M--------------------------------------ALGALLLLLGVLGTPLAP---------------------------------GARGSEAEGQLIKKLFSNYDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAE----HDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGEERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAG-EKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQ-MPFWVRQIFIHKLPPYLGLK----RPKPER---------DQLPEPHHSLSPR---------SGWGRGTDEYFIRKPPSDFLFPKLNRFQPESSAPDLRRFIDG---------PTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDA-----------------TYHLPPPEPFP-----------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: *: **. . : : : : :::* .:: :: : * ::: * * :* : . .: : :.:. :* *:: * :* * : :. : * : * *. ::*:* :.: :**:* * * : * * :*: : : :. : . :* * . : : : ::* .:** : :* **: :: * :..::**.. * :* : *: ***:::: . :* :* :*:: .**:* * ..:: : * .:*: *:. *: . :: :: .* : : .:: . .:* :. .:*.. :: *: :: ", "identical_positions": 59, "similar_positions": 130, "identity": "9.15%" }, { "cls_id": "homologset.agr.FB:FBgn0004132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R7-1", "uniprot_id": "MESD_RAT", "id": "Q5U2R7-1", "name": "LRP chaperone MESD", "aln": "MAASSWLRAVLLFLCASD----LLLLSPPEAYATD----TPGEAITPPRKKK-DIRDYNDADMARLLEQWEKDDD-IEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTISGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVNQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKGKKK-EGDPKPRASKEDNRAGSRREDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERE7-1", "uniprot_id": "MESD_MOUSE", "id": "Q9ERE7-1", "name": "LRP chaperone MESD", "aln": "MAASRWLRAVLLFLCASD----LLLLPPPNAYAAD----TPGEATPPPRKKK-DIRDYNDADMARLLEQWEKDDD-IEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTVSGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVSQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKAKKK-EGDPKPRASKEDNRAGSRREDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14696-1", "uniprot_id": "MESD_HUMAN", "id": "Q14696-1", "name": "LRP chaperone MESD", "aln": "MAASRWARKAVVLLCASDLLLLLLLLPPPGSCAAEGSPGTPDESTPPPRKKKKDIRDYNDADMARLLEQWEKDDD-IEEGDLPEHKRPSAPVDFSKIDPSKPESILKMTKKGKTLMMFVTVSGSPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVGQDRCADVTLEGQVYPGKGGGSKEKNKTKQDKGKKKKEGDLKSRSSKEENRAGNKREDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L243-1", "uniprot_id": "MESD_DANRE", "id": "A1L243-1", "name": "LRP chaperone MESD", "aln": "MASSVGCRTLSVLF---------LLVLFITVHCTD----------TKPKKKK-DIRDYNDADMARLLEEWEKDDD-IEEGDLPEHKRSPPPIDFSKIDASKPEELLKMSKKGKTLMVFASVSGNPTEKETEEITGLWQGSLFNANYDVQRFVVGSNRVIFMLRDGSYAWEIKDFLVSQDRCEDVTVEGQVFPGKN--AKKDAKGKEQNETKK-KGDKK-----AANRANKGKQEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T9B6-1", "uniprot_id": "MESD_DROME", "id": "Q8T9B6-1", "name": "LDLR chaperone boca", "aln": "MQT----RLVLLLLALTP------LVLAKKFKEEE----------KPAWAKK-DIRDYSEADLERLLDQWEEDEEPLEDDELPEHLRPQPKLDLSNLDSKSPEDLLKVSKKGRTLMTFVSVTGNPTREESDTITKLWQTSLWNNHIQAERYMVDDNRAIFLFKDGTQAWDAKDFLIEQERCKGVTIENKEYPGVN----------------------------------AKKDEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * ::: *: : . ** *****.:**: ***::**:*:: :*:.:**** *. . :*:*::*. .**.:**::***:*** *.:::*.**.:*:: ** *** **:* : :.:*::*..:*.**:::**: **: ****: *:** **:*.: :** . :::*", "identical_positions": 72, "similar_positions": 67, "identity": "30.64%" }, { "cls_id": "homologset.agr.FB:FBgn0004167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JY25-1", "uniprot_id": "A0A0G2JY25_RAT", "id": "A0A0G2JY25-1", "name": "", "aln": "--------------------------------------------------------------------------------MRTWTS----AAKVGIRIQNLYTELADGAHLLRLLELISGEALPAPSPGRLRVHFLENNSHALAFLRAKVPVPFIGPENIVDGDQSLILGLLWVIILRFQISHISLDREEFGASAALLSAKEALLVWCQRQTASYSNVDITDFSRSWSDGLAFNALLHAHRPDLLDYGSLS--LDRPLYNLSFAFRVAEQQLGIAQLLDAEDVAARHPDERSIMTYVSQYYHYFSRLQQGQTARRRLAKVLLQLQETEVLQAQYEQLAADLLCWIEEKQMQLEAQDFPDSLPAMRQLLSAFASFRAQEKPPRLQQQGASETLLFQLQTTLRAQNRRPFLPREGLGPAELAQCWAELERVEASRSQAMQQKLLQLERLDTLARRFQCKASHRESFLNDAEQMLEQARAS-LTDPATVEAATQRLNMLEAGLLPQEGRFQALGEMADILQQEEYHSWADVACRQKEITGRWRRLLQCLQEERKCLAGTQAVLSLLQEVEAATDQLGELQGLAGSTACEPQLAEVVLLLQSHDLLEAQVSAHRTHVNRLVHQTAQLDSSQGTSVQTLQTKALALDELHHSLVSLVRTRRTLLEQTLQRAQFLHSCEEEEAWLQEHRQLVEKAAPGRDLTQIANALQKHKALETELHRHQAVCIDLMQRGRNLSVKEPLTQPDPLERAEAVQGIWQLLWTGAARRRTRLQTALLVGQYFSDLAEAASWLLQRQKQLESASYGKDQSDSEALLQQHLRLEQGLCAFAVDLRELEDQARAAAALVSQMVHTGTREGPRHVPPTPN-----------------------------------------------------------------------------------VLSALGLP--------GEDPR----------------------------TAPQAEYDFHFDSNAILQAQADLRQNYENLRALAKLHRARLEETVTLFSFYSSCRELQSWLEAQTALFQTLQPQGDNLEVTQLKYENVLMTLATGKGHWEEAISTAEQLKQRCPGHISKIQQQQEELKHR-WQQLEALKEEKLLQLTRAMEVCSLLQESEPTRAQLLSVISRLEALGTRSSG----DSHRTLQQTQQKVLVLEKKISYCQKATIELMESGPAEGRLLWEQVLMLQSLLKQAQGQVAQQVQVQTKDRVQRGILQESQKLLLWAEGIQAQLCSKEQLEDVASAQQLLRKHGALREETCLWKERLQQLEAQGQLVAVSGSPQF-QEVASALRLLGQHSQQLKALWEQRQQKLWAGLELQRFGQEVDSFTATCASHEASLQLDNLGEDIREAQSLLQQHQGLGWLHSSLGSRAETLWARGEKLLLNHPTAVHRIRELLHSAQAQWARVQERSDQRRGQLLASLQLQEWKQAAEGLMLWMEEKWPRVADEGPQTGSNILQ---WHKITKSELLASHKYMEDLQQTGKELLHSNPYAQEDIQDRLQSLNHKWEELSHKTAEQGDRLPQTRQQGQLLELLQDVRGMMEHLEGALQSTETGQDLCSSRRLQTQHRQLEGKSQALASKMAALISQTHNVFT-----SWTILEESQKCQQRFKSLQSKLATRQQQLQASVELHKFNLLSNLELTWVAEHMPSTSPIYPAQCWHDAQSLQRKHKVLQAEVKGHVGHMHRVLSTGQSLAASGHPQAQHILEQCQKLEGHWAELEQACEGRAHCLQQAVIFQRYLLNVSEMETWVEEKLPLVSSRDYGSNEEATFGLIRKHQMLRQEIALCWGSMEDLEQRFQTLAGFEASER--LVVVREKL----QALQKLADDRGQELEGTLRLHEFMREAEDLQSWLDSRKQVVRGEHGFGEDHEHVLQLCTEFTKFQHQVETGAQRVETCRQLAESLLELGHSAAHKSHQRQQDLQAAWCELWQLTQAQGLLLSDAETTLRVHRDLLEILSQIQEKATNLPNDVAQDLHGVEKQLQRHEGLERELAGMEQ-------------------QALATVQQKQQAVTQAWEALQLRMEQRKAQLEQAYLLVRFHTAVRDYTSWVASVHLELQMEDDSWEPSSILLRLRAHQWLWAELKAREELQEQGTKMGQQALLVARTP-TKVQDGLQTLQEKRDQVFQAWALKQERLQATLQEQRLLRQGDHLVKLLTAQEAFLKASGLGSSVEEVEQLIRKLVIFQKVLALQDKKESALCEQLKMIPSP--------KGQNLVYHVQERRAQVKELAESRGQALRTSLMIGNFTRTATQVEDWIQERLQQLRACS----PLGNLKDYLKHLRKHQAFRAEVQAHEQIVTSVAKQGEGLLSQSHPQAREVSQRLEALWDLWEKLRQAVTLQGQALEDRCNFLEFLQSADLAETWIQEKERMVDGCDVGLNLEHCLQLCRQVCKLQ------VTVDDTRIRRIKNLSLQLK--NQGPEESEAICQRQNQLNNRWKTFHGNLLLYKQRLEAALERHRLSSELDNIIEQIREKESLAQALEGTEGLE---RISWRQKMLQQEMDLIQTQVESLGGRVSRLCEENPE-ATGGLRHKQQEMMDSWWKVWHKARKWRELLDVGHEVQKLQTMLQDLQDWAQGLQAEMARQATPCSPVRILYMLEEHQAHKVELDVRTDSLNLVRSMGQRLLASG-YPLASGIRQPLAAVEQELSGLQASWQGRQQQLQQALEQQLCLSSVEKVEHWLDSEEASLTYEEVADPLVTVEILLSKHKRREQGLKVQAEKISALEATAHSLHQGGHSEAHSVLDRCQALLLRMDALTEQARARGRQLEELQKLRKFLQDSSEVATWLREKNLVALEEGQQDPTTMQAQLQQQQNLQAELDASVHQRQELQMEGQELLQGGHPASETIRGQLEELGGLWAELQTNCQRKMARLQGASKVLHLQRMLRELKNWLEPMEAELRAPVRSQDLPRVGELLGAQEELEAAVDRQARQVQELQGQAQACFQEGHRLAKDVEEQAGQLLQRFQGLWEPLQERRASLEAQRLLLQFFRDVDEEMAWVQEKLPSATAQDYGQSLGTVRHLQEKHQNLENEISNHKALSQVVTGTGHKLVQAGHFAAEEVAARVQQLEVALNHLETEAARRGRMLQQALEAQQTLVELLEAGSWLAERGHILDSEDLGQDTEATQALLRRLETTTRDLEGFSSRIEQLQQTVALLESGQGPGSPRVLAQLQAVREAHAQLLQRAEGRGQALREQLHLYQLEQEALLLDAWLTTKLTVAESQDYGQDLEGIKVLEDMFDAFNREVQSLGQAKMQTLRELMASLERGAPRFYPQIQAQKCRVQATWERLNKAIKARTENLAAARDLRSFEQAASELQGWMQETTTLLEGEFQVHDLSPAQPLLQQQQQQ---------------------RRLQREVRVIENEVSRVQTEAQRLGQHHPLAQGSLGEWLTKVQGAWANLEAKVQEWSQKLLQATQGHTFLGSCRELLVWAQEKQELLSSEKQAEDVVGAKQLLEQHEELEQEIQECCLQAQNARQEGQRLLDKGHFMSLEVAECMQELERHVQELQVAWALRGQRLEQNWSLQQLRQRLELAEAWLTSCECLLLDPSCGHSVLDVERLLYRQDGLEKLLAAHEEKFTQLQMMT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEAKGAHVMEASVEL------------------------------------NQQPPTEGRQPGTSFWTSSHGILARGASSLFSDMRKVEVPSG-------------------------------IGELPYASP---------LVPEETECERLE----------------------------------DRKQTFFPRSKP----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BF02-1", "uniprot_id": "A0A571BF02_MOUSE", "id": "A0A571BF02-1", "name": "", "aln": "--------------------------------------------------------MDSEYEIGHVRKLQAQHTHMQEKTFTNWINNIFRLGRVGIRIQNLYTEFADGAHLLRLLELISGEALPAPSPGRLRVHFLENNSHALAFLRAKVPIPFIGPENIVDGDQSLILGLLWVIILRFQISHISLDREEFGASAALLSAKEALLVWCQRKTAGYTNVDITDFSRSWSDGLGFNALLHAHRPDLLDYGSLS--PDRPLYNLSFAFRVAEQQLGIAQLLDPEDVAALHPDECSIMTYLSQYYHYFSRLQRGHTAQRRLAKILLQLQETEVLQAQYKQLVADLLCWIEEKKMQLEARDFPDSLPAMRQLLAAFASFRAREKPPRWQQRGATEALLFQLQTTLRAQNRRPFLPREGLGPAELAQRWAELERAEACRSQAMQQRLLQLERLDTLARRFQCKASHRESFLNDVEQMLDQARAS-LTDPATVEAATQRLSVLEAAILPQEGRFQALGEMADILRQEEYHSWADMARRQKEITGRWRRLLRCLQEERKRMEDSKAVLSLLQGVEAVTHQLGELQVLASSTVYGQQLAEIVSLLQSHDLLEAQVSAHRTHVTHLVHQTTQLDS-QGTSVEVLQAKALALAELHHSLVSLVRARRTLLEQTLQRAQFLRSCEEEEAWLQEHRQLMETAVLDRDLTQIATALQKHKALETELHRHQAVCVDLMQRGRNFSVREPLTQPDPLERAEAVQGTWQLLWAGAARRRARLQTALLIGQYFSDSAEAASWLFQRQKQLESASCGKDQADAEALLLQHLRLEQDVRAFAAELRELEEQARAAAALVSHMVHTGTWKGSRLVSPTPNEE-----------PPEDWKRLGRDTIGGPQGETQVLAAPGSHYSHQQIAFFSREEAPNTWKLEELGDSQSRMAIIHSIEKKPQVLSALGFL--------GEGPR----------------------------TVLQAENDVHFNSSTILQAQADVSQTYEKLRALAKLHRTRLEESIALFSFYSSCRELQSWLEKQTALFQTLQPQGHNLEVIQLKYENVLMTLATGKGHWAEAINTAEQLKQRCPGHISKIQQQQEDLKQRWWQQLEALKEEKLLQLTRGMEVCSLLQESEPIQAQLLNVISRLETLGTRSSG----DSHHTLQQTQQKVLVLEKKISYLQRATIEVMESGSPESRLLWEQVLMLQSLLKQAQGQVARQIQVQTVARVQRGILQESQKLLLWAEDIQAQLCSKEERQVEASALRPLRRHGTLQEETCLWEERLQQLEAQGQPVAVSDSPQS-QEVASALRLLGQHSQQLKALWEQRQQKFWEGLELQGFGQEVDDFMATCASHEALLQLDNLGEDIREAQSLLQQHQGLGWLRSTLGSRAEALRARGEKLLLSHPAAVSKIRELLHSAQAQWTRVQERSEQRRVQLLASLQLQEWKQAEEGLMLWMEEKWPRVADERSQAGSNILQKLKWRKITKSELLASRRYMEELQQAGKELLHSNPYAQEDIQDRLQSLNHKWEELNHKMEDRGDRLPQTRQQDQLLELIQDVQETMEHLEGALQSTETGQDLCSSRRLQRQHCKLEDKSQALASKMDALISQTHNAFT-----SWTILEESQKCHQRFKSLQSKLATQHQQLQASVELYEFNLLSNLELTWAAEHMPNAALNCPAQCWHDAHSLQRKHKMLQAEVKGHVRHMYRVLSSGQRLAASGHPRAQHIVEQCQKLESHWAGLEQACEERAHCLQQAVTVQQYFLNVSEMETWVEEKRPLASSQDYGSNEEATSGLIRKHQMLQQEVALYWSSMEDLEQRFQTLAEFEAPER--LGVVREKL----QALRKLADERGQELEGTLRLHEFMREAEDLQSWLSSRKQVARGGDTFGEDHEHVLQLCTEFTKFQYQVETGAQRVETCRLLAESLQERGHSAAPKAHQRQQDIQASWSELCQLTQARSRLLNDAEITLRVHGDLLEVLTQIQEKATSLPNDVAQDLCGVENQLQRHERLERELAGMEQQVQELMKAGGRVQELCPGTQALAAVQQKQQAVTQAWEALQLRMEQRKAQLERGYLLVRFHTAVRDYTSWAASVHQELQMEEASWEPHSLLLRLRAHQWLWAELKAKEELQQRATKMGQQALLAAGTP-AKVQDGLRTLQEERDQVFQAWALKQEKLQAMLQEQHLLRQCGHLVEVLTAQEAFLKASGLGSSVEEVEQLIRKHVIFQKVLALQDKKESALNEQLKTISSP--------KGQNLFCHMLEHRAQVKELAESRGQALHTSLMIGNFVRAATQAEDWIQQRVQQLRAWS----PLGNLKDYLKHLRKHQAFRAEVQAQEQILTSVAKQGEELLSQSHPQAGEVSQRLEALRDLWEKLRQAVTLQGQALENRYNFQEFLQRVDLAETWIQEKERMVNSCDIGLNLEHCLQLCRQVRRLQ------VTVDDAHIKGIKNLSLQLK--NQGPEESETICQRQNQLNNRWKTFHGNLLLYQQRLEAALEIHRLSRELDDVIERLREKESLIWAPEGTEDLENVQRLSWRQKVLQQEMGLIQTQVESLEGRIGRLCKESPE-VAHSLRHKQQEMMDSWWKVWSKAQKWRELLDVGHEVQKLQTLLQDLQDWARGLQAEMATQGTPCSPVRIQYMLEEYRAYKVELDIRTESLNLVQSMGQRLLASG-YPQASEIHQTLAAVEQGLSSLRESWQGRQQQLQQALEQQLFLGSVEKAERWLDSEEASLASEGVADPLVTVETLLSKLKRHEQGLKAQAEKIRALEATAHSLHQGGHSEARSILDRCQALLLRTEALTEQARARGHQLEELRKLRTFLQDSNEVTAWLREKSLAALDEGQQDPATMQTQLQKQQNFQAELDASVHQQQEVQMEGQKLLQGGHPASETIRGQLEELGGLWDELQTNCQRKMARLQGALKVLHLQRMLKELEKWLEHMEAELRVPVRSQALPRVGELLGAQEELEAAMDRQAKEVQELQGQSQACLQEGHCLAKDVEEQARQLLQRFQSLREPLQERRASLEAQRLLLQFFRDADEEMAWVQEKLPSATAQDYGQSLNTVRHLQEKHQNLENEIHSHKALSQVVTGTGHKLIQAGHFATEEVAARVQQLEVALNRLETEAAQRRRRLQQALEAQQTLVELLEAGSWLAERDHILDSEDLGQDAEATQALLRCLEATTRDLEGFSSRIEQLQQTVALLESGQTPGSPRVLAQLQAVREAHARLLQRAESRGEALREQLHLYQLEQEALLLDAWLTTKLAVAESQDYGQDLAGIKVLEDMFGAFNREVQSLGQAKMQTLRERMASLERGAPRFYPQIQAQKCRVQAAWEGLNKAIKVRTENLAAACDLRSFEQAASELQRWIQEKTTLLEEAFQVHSLSPSQPLLQQQQQQQQQQQQQQQQQQQQQQQQQQHRRLQRELRAIEKEVSRVQMEAHRLGQHYPVAQGSLSEWLTKVQGAWTNLEAKVQEWSQKLLQATQGHTFLGSCRELLAWAQEMQELLSKEKQAGDVVGAKQFLEQHEALEQEIQERCLQAQTIRHEGQQLLDNGHFLSPEVAECMQELERHLQELQVAWALRGQRWEQTRSLQQLRQRLELAEAWLASWERLLLDPSCGHSVLEVERLLYRHEGLEKLLVAHEETFIQLQTMT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEAKGGHVTEASVE--------------------------------------QQPPTEGRQPRTSFPTSSHGILARGASSPFSDMRKAEVPSG-------------------------------TGELAYVSP---------LVPEETECERLE----------------------------------DRRQTFFPRSKP----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRC6-1", "uniprot_id": "SPTN5_HUMAN", "id": "Q9NRC6-1", "name": "Spectrin beta chain, non-erythrocytic 5", "aln": "---------------------MAGQPHSPRELLGAAGHRSRRPSTELRVPPSPSLTMDSQYETGHIRKLQARHMQMQEKTFTKWINNVFQCGQAGIKIRNLYTELADGIHLLRLLELISGEALPPPSRGRLRVHFLENSSRALAFLRAKVPVPLIGPENIVDGDQTLILGLIWVIILRFQISHISLDKEEFGASAALLSTKEALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHAHRPDLLDYGSLR--PDRPLHNLAFAFLVAEQELGIAQLLDPEDVAAAQPDERSIMTYVSLYYHYCSRLHQGQTVQRRLTKILLQLQETELLQTQYEQLVADLLRWIAEKQMQLEARDFPDSLPAMRQLLAAFTIFRTQEKPPRLQQRGAAEALLFRLQTALQAQNRRPFLPHEGLGLAELSQCWAGLEWAEAARSQALQQRLLQLQRLETLARRFQHKAALRESFLKDAEQVLDQARAP-PASLATVEAAVQRLGMLEAGILPQEGRFQALAEIADILRQEQYHSWADVARRQEEVTVRWQRLLQHLQGQRKQVADMQAVLSLLQEVEAASHQLEELQEPARSTACGQQLAEVVELLQRHDLLEAQVSAHGAHVSHLAQQTAELDSSLGTSVEVLQAKARTLAQLQQSLVALVRARRALLEQTLQRAEFLRNCEEEEAWLKECGQRVGNAALGRDLSQIAGALQKHKALEAEVHRHQAVCVDLVRRGRDLSARRPPTQPDPGERAEAVQGGWQLLQTRVVGRGARLQTALLVLQYFADAAEAASWLRERRSSLERASCGQDQAAAETLLRRHVRLERVLRAFAAELRRLEEQGRAASARASLFTVNSALSPPGESLRNPGP--------------------------------------------------------------------------------WSEASCHPGP--------GDAWK----------------------------MALPAEPDPDFDPNTILQTQDHLSQDYESLRALAQLRRARLEEAMALFGFCSSCGELQLWLEKQTVLLQRVQPQADTLEVMQLKYENFLTALAVGKGLWAEVSSSAEQLRQRYPGNSTQIQRQQEELSQR-WGQLEALKREKAVQLAHSVEVCSFLQECGPTQVQLRDVLLQLEALQPGSSE----DTCHALQLAQKKTLVLERRVHFLQSVVVKVEEPGYAESQPLQGQVETLQGLLKQVQEQVAQRARRQAETQARQSFLQESQQLLLWAESVQAQLRSKEVSVDVASAQRLLREHQDLLEEIHLWQERLQQLDAQSQPMAALDCPDS-QEVPNTLRVLGQQGQELKVLWEQRQQWLQEGLELQKFGREVDGFTATCANHQAWLHLDNLGEDVREALSLLQQHREFGRLLSTLGPRAEALRAHGEKLVQSQHPAAHTVREQLQSIQAQWTRLQGRSEQRRRQLLASLQLQEWKQDVAELMQWMEEKGLMAAHEPSGARRNILQTLKRHEAAESELLATRRHVEALQQVGRELLSRRPCGQEDIQTRLQGLRSKWEALNRKMTERGDELQQAGQQEQLLRQLQDAKEQLEQLEGALQSSETGQDLRSSQRLQKRHQQLESESRTLAAKMAALASMAHGMAA-----SPAILEETQKHLRRLELLQGHLAIRGLQLQASVELHQFCHLSNMELSWVAEHMPHGSPTSYTECLNGAQSLHRKHKELQVEVKAHQGQVQRVLSSGRSLAASGHPQAQHIVEQCQELEGHWAELERACEARAQCLQQAVTFQQYFLDVSELEGWVEEKRPLVSSRDYGRDEAATLRLINKHQALQEELAIYWSSMEELDQTAQTLTGPEVPEQ--QRVVQERLREQLRALQELAATRDRELEGTLRLHEFLREAEDLQGWLASQKQAAKGGESLGEDPEHALHLCTKFAKFQHQVEMGSQRVAACRLLAESLLERGHSAGPMVRQRQQDLQTAWSELWELTQARGHALRDTETTLRVHRDLLEVLTQVQEKATSLPNNVARDLCGLEAQLRSHQGLERELVGTERQLQELLETAGRVQKLCPGPQAHA-VQQRQQAVTQAWAVLQRRMEQRRAQLERARLLARFRTAVRDYASWAARVRQDLQVEESSQEPSSGPLKLSAHQWLRAELEAREKLWQQATQLGQQALLAAGTPTKEVQEELRALQDQRDQVYQTWARKQERLQAEQQEQLFLRECGRLEEILAAQEVSLKTSALGSSVEEVEQLIRKHEVFLKVLTAQDKKEAALRERLKTLRRP--------RVRDRLPILLQRRMRVKELAESRGHALHASLLMASFTQAATQAEDWIQAWAQQLKEPV----PPGDLRDKLKPLLKHQAFEAEVQAHEEVMTSVAKKGEALLAQSHPRAGEVSQRLQGLRKHWEDLRQAMALRGQELEDRRNFLEFLQRVDLAEAWIQEKEVKMNVGDLGQDLEHCLQLRRRLREFRGNSAG-DTVGDACIRSISDLSLQLK--NRDPEEVKIICQRRSQLNNRWASFHGNLLRYQQQLEGALEIHVLSRELDNVTKRIQEKEALIQALDCGKDLESVQRLLRKHEELEREVHPIQAQVESLEREVGRLCQRSPE-AAHGLRHRQQEVAESWWQLRSRAQKRREALDALHQAQKLQAMLQELLVSAQRLRAQMDTSPAPRSPVEARRMLEEHQECKAELDSWTDSISLARSTGQQLLTAG-HPFSSDIRQVLAGLEQELSSLEGAWQEHQLQLQQALELQLFLSSVEKMERWLCSKEDSLASEGLWDPLAPMEPLLWKHKMLEWDLEVQAGKISALEATARGLHQGGHPEAQSALGRCQAMLLRKEALFRQAGTRRHRLEELRQLQAFLQDSQEVAAWLREKNLVALEEGLLDTAMLPAQLQKQQNFQAELDASMHQQQELQREGQRLLQGGHPASEAIQERLEELGALWGELQDNSQKKVAKLQKACEALRLRRSMEELENWLEPIEVELRAPTVGQALPGVGELLGTQRELEAAVDKKARQAEALLGQAQAFVREGHCLAQDVEEQARRLLQRFKSLREPLQERRTALEARSLLLKFFRDADEEMAWVQEKLPLAAAQDYGQSLSAVRHLQEQHQNLESEMSSHEALTRVVLGTGYKLVQAGHFAAHEVAARVQQLEKAMAHLRAEAARRRLLLQQAQEAQQFLTELLEAGSWLAERGHVLDSEDMGHSAEATQALLRRLEATKRDLEAFSPRIERLQQTAALLESRKNPESPKVLAQLQAVREAHAELLRRAEARGHGLQEQLQLHQLERETLLLDAWLTTKAATAESQDYGQDLEGVKVLEEKFDAFRKEVQSLGQAKVYALRKLAGTLERGAPRRYPHIQAQRSRIEAAWERLDQAIKARTENLAAAHEVHSFQQAAAELQGRMQEKTALMKGEDGGHSLSSVRTLQQQ------------------------HRRLERELEAMEKEVARLQTEACRLGQLHPAAPG----GLAKVQEAWATLQAKAQERGQWLAQAAQGHAFLGRCQELLAWAQERQELASSEELAEDVAGAEQLLGQHEELGQEIRECRLQAQDLRQEGQQLVDNSHFMSAEVTECLQELEGRLQELEEAWALRWQRCAESWGLQKLRQRLEQAEAWLACWEGLLLKPDYGHSVSDVELLLHRHQDLEKLLAAQEEKFAQMQKTEMEQELLLQPQELKPGRAGSSLTSFQWRPSGHQGLGAQLAETR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPQDAKGTPTMEGSLEF------------------------------------KQHLLPGGRQPSSSSWDSCRGNLQGSSLSLFLDERMAAEKVASIALLDLTGARCERLRGRHGRKHTFSLRLTSGAEILFAAPSEEQAESWWRALGSTAAQSLSPKLKAKPVSSLNECTTK-----------------DARPGCLLRSDP----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T6Z4-1", "uniprot_id": "A0AB32T6Z4_DANRE", "id": "A0AB32T6Z4-1", "name": "", "aln": "----------------------------------------------------MEKRVDGEESDGRFRELQEQRMTVQKKTYTKWMNSVFSKSGEKVVLTDVFTELRTGVHLVRLLELISGEKLPTPSRRTLRVHCLENNSIAITFLKSKIRVDLIGPENVVDGDRTLILGLIWIIILRFQIGNINIVEAGGDASAARRSAKEALLIWCQRKTAGYTNVNVQDFSGSWRDGLAFNALIHAHRPDLFDYNRLR--QDDPKRSLTHAFALAEDEFGIMQLLDVEDVMVPHPDEKSIMTYVSLYYHYFSKMKQGQTIQKRIAKIVDLLKELDDMKGLYESMVSDLLRWIKTKVVELNDRSFPNSLREMQHLVAAFKKYRTIEKPPKYQERGAIEAHLFDLRTKLRANNQRDYIPPEGKTLGDIERNWTLLERAEHQRERVLQSALMRLEQLEQLAQKFGRKATLRESYLEDTLQLIQQQDLGGLQRLEEAEIAARRLEALGADVLAHEPRFRALSEMAAVIERDNYHSKVQVIRRNVDIMNRWKDLKQVLQEQRAHVGDAANTFAVLRDIELISMDLKELQAQADSSDMGKQLPDVVALLQKQDLIDTQIISLGETLNAISSSSALKVKHKGAT--KVQRELKDLNSHYNSLLGLSKNRRKALEGQLKLFEFFHDCEEVEAWIYEKWVLLQAASLGRDLSQIQQAIQNHKALEAEIQSQESLCSGVVFRGQELCRGRHPNENDIQKWIRTLQKQWQQLKEQVTIRKNRLHAANVIKQYFADITEASSWLDDHKPLLIDEDYGKDEASSTALLQRHQRVEKEMEAYSLEVKRLGEQAKSAAQLAPLTTETQQTRMVHYSDSSDGED-----------EKEKKADKGGKAVSKILPQEQAMIRFKYRGPKLIWDRGEILTIISREKDDKLLLRDSRGNEQLVSSTYIRELPVSQEAPPETTNGVAESPKRKVSRPRR----------TRSMRRGTAEISTSTLPDPHFQKDTIESTQNSLEKDFNRLYNLAQSKNKILEDTARLHRFYNACEEFESWMGDKENVLNTFSSNSNNLEVVQAKYENFVTELASGRKQLDDITKFGDELLKQQHSRKKDIQQRLGIVTRR-WERIQKLKDEMAHELLSSADVKSFLQTCQEVQAQLQHRLAQLDTPDVGSSLSALQAEEHRQAQAERDIEALERKIDYLKSVAKMKKDCSPAESAAIMEEVHALEDLLRQLKAQAIQRQRMLEEARRLQLFQKETRDLLMWAEATQEHLLEEETGSDVASAQALLKENLDLKQEIKLQKAKLKDMERLGQSLDVASGEKGGKDVQQTLTKLDHEWSQLDKLWSSRNRRLEQGLEFQKLNMEADRIEATISGHEARLKVRDLGDSVDSVHSLLSRQEELEALLEALERSIILFQDKCQELISKRNFAAKEIQQRSKVIQDHFKRLKESCKLRRLELLASKKYQEFLRDAEEMLLWMDEKFEIAEDESYRDPTNILRKLKKHEAAEKEMQANAVRIDRLIETGEEMLAEDHYNTQSIQKKTQEVHKRWIELQRKMAERGDKLRQAGQQEQLMELLQDAKLKIEAIERMLQNAIRGHDLRSSRQLLKEHKQLEEEAQELAEKINSIVTRAKNLATN-HFDSQRILKETDTYLKLFKSLENPLDHRRSQLEADVDLYSFYHDVDLELNWISEHQPVADTTNYERSLVGAVSLFQKHKDLQAEVNAHSKYLQRVLDRGRAMARSNQWNGQEVQQRCEQLIAKWEELEESCKKRSGELNRAVTREQILLDCTELETLVSETSALVST-DYGKTELATRSLIKQHEGVEGQIEVLAAQVDELKSNVKQAVRVWGLEE--LNKPCNHIKSKLSELQHSATVREQRLRETLHLHEFKRETSELEEWIAQQTQIAASN-DLGSDYENAMQLRGRFEVFLKQLEVGKERMHTCEQLADKLIKSNHPESRFIRETQNLLRESWDELQDLSKDRKEKLRKSEKCHKFYKDLTDALGQIKERHKTIPEDIAKDLKGVQSQLRKHEALVHELAGTEQQLQELLDGTDAILGMCS-PELRVGLQELQQEVVENWERLRMRMEQREEELQSAKDRYMFLNTAQDYSLWCSQVLSWMKAEESIRDVATCDLQLFQHQQLWAEIVAREETFAQAVSMGQGLLENDIPNAREIQEKLKVLQEEREKLSDNWQLRQKWLENTYLEQVFYRDTEYMEKITNSQEIQLKNSDLGTTVDDVESLIKRHEAFEKLLHSQEDKMVALQESAERLKTEGLTREKNSNVKNKLKALQERRERIKDLSDKRREDLEVSKLHCIFSRDVSEAEEWITDRMNKIQEDSK--MDMSNLQTKMKMLQKHQVFEAEILAHGNIIESVQQAGNELVTMHHPKSKEIRQTVSALISHWEALKQELAVRGKVLEDNRDFLEFLQKVEQVEVWIRQKEVMINVGDVGEDYEHGQQLLKKLSEFRGSGSGDVTVDDAHIKTINTLAARLE--RQNSDELVTVKKRRQQLNERWRNFHGNLSSYKRKLEAALEVHALIRELEEVRDRAGEKMLLLQGQGCGVDVESVENLIRRHEEMEREARVIQERGAALEKETKDRLKRHCD-LSDKLSKKQEEVNIALVKLDKEIKRRKERLQESHQLQLFKANQRLLLDWTLKQSDEMVKKGLPKNKTEAESFILEHHDWKAEIDARGDRIDSVKSFGQNLVKSG-HSDAAEIKEALRKLDDAKTMLTRAWEDRRKTLDQALKLQIFLGYADQTESWMSNREAFLINEDLGGSLSEVEALQRKLALFENSLEAQMEQVSEVDRYAQQLIQANHYDSDNIKKRTKAILLRKERILEMSKSRRKALEESLQLQKFLEASYEISSWLNEKNSVAVDESWKDPINLQAKLLKHQSFEAEILANRNRVQAHIKDGDNMLAFSHPAKSKIKPRIKDVDDNWDQLLSNCKHKKTRLQQAYQALQFQRSLGDIEEWLGSVEVEVANDDYGGDLASVSRLLKALQGLEEMVDAHMEKVQGLVDTAKDFSSQGNFLADNIQQRVWEVVNRYNGLAEPMQTRRETLESWQLLFQFYRDLEDELLWIEDKLQATATKDWGTSLQSIQSIVKKHLVVMQEIENRTPLIMAVQEAGQNLVRGRHFASREISEKLSGLKKNFDALKKESANKDRLLQQALKIQSFLSEVSQLEQWMEEQKPVLESCDYGKNEEATEAFLRKLDTVDLELESQRGKVEALLKTGTDLEKSQHPNSHLVSKSLEDMQGEFETLLQLSGERRTELENQYNFYIFERDARDLQTWLLSRKTIAESDDYGKDLEGVEALQKKFEDFSEEVGTLGQSKLSTVQKLKQSVQS------ADAQQKEKDLLKLWEDLNKAMKARAENLHSAREVHQFEHDLDELRIWMNEKEVALDSEELKNDLLSVQALIRQ------------------------HEGLERDLAVIEEDVSRRKEEGKALVRRSPRVRDSLSKRLQEVEEIWRNLLEKANQRRQRLQQAEAVQRYLIEWREMMGWLKETLSLMTGEGFGGKVKDLEQMIKKHDEYRTQIDRQLDKSEMVKNDGRRLMEEGNSWSHELEERLAELKDLEVRVLEAWTERRAQYQEDIELQQLQRELEQAEHWLNTYESALRAEDYGESVSDVLDLMKKQEDLEAMIQAQSERFNALQARRTQRENKMKEIQRGDSTDSSRDKPVRVTSLKRKPSERPALPPRPLLTSPVLKNSDSPTPSRVPTPRSALWESRSDKTDSPVVSRVAAGLRRKSSSDSDSVTSPDKPSTSGQDSPDSSSTAVYRPHYPHNASKVKHTTSSQDEVDTLRETESFLKTIDKPKITPRRQKPSTPDKELWGPPTSKPPEPPIKPSQSLSRSPQ---------------------------------------------------------------SLSRSPEPLSRSPEPLPRSPEPLSRSPEPLSKSPEPLSRSPEALSRSPEPLPRSPQSLSRSPEPLSRSPESPYIPPLTKPPSTNPPDPPSKVTELVDNQDSEDRNLPQSTPPSVPQSSPQSFVSNPEPQASSSVESSIVFPAAST-------------------KIRAEDAKMEGTLEIKLKQGGNTGLDHWETVYALLEEETLNLFKDQDAASENCTRWPPINLAGAICKDNPFYRRKEHTFKLMLSDGSHYLFAASSQGEQQKWLKELQECINPTVSSDNPGMKRESSSESVEKSESVPVDTSDTQDQEKEDSTESCETEREPPPKPPHTYYNKHKYPDGGESQDSVSVSQNIKG---------------LQPPTFAPPPPPTQNQTENEAKAKNRSGFMKFFRK------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNJ6-1", "uniprot_id": "A8JNJ6_DROME", "id": "A8JNJ6-1", "name": "", "aln": "MEYNSVLRSNFSRNEYRRYISYERQSLASQYEPGGYSALQTPTPSNRNSANMTQRDGIIKFENERIKTLQEERLHIQKKTFTKWMNS--FLIKAKMEVEDLFTDLADGIKLLKLLEIISSEKLGKPNSGRMRVHKIENVNKSLAFLHTKVRLESIGAEDIVDGNPRLILGLIWTIILRFQIQEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHRPDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYYHTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSD-----PRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIK--SDEGEGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQI-WQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLG--KQLSDGKPNMAETVAVIERLKAEQDAIHRGWAEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAG-NRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSE-DYGQDFEHLQLLQNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYP--SNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQR--HYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDS----DMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEK--LLHADHVDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNAN-EARVEACLERGDRLIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASLISEDYGQDLESIQALGRK------------------------HQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDKIKVLQARHELLKHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDFEKTVAAQEEKFQAIKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQLRPPFGDDNEHLALQKSSSSGMFGDRLRRGSADANVKRAESMKVQPKQAKRTPSFTTRRRAQSFRKNQKGEGFDLPPVEIQGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQKTATAPVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKISFHASLPPNMQLLSYDESMKQQSSSSPDIKVTSSVESPVSSRNSSPDSQRRTSGAQVLDGTATPQMAFLQRQMQQQQQQQQSQPSSPTGGFDQKPPIPPRGAAPVASHRQSQENLVVMRNRQSSNDLQQSATLPAGLTGVQQNGNGKDDNALLTRNSEARQSDNPPPLPTTMPPVGGQHQHPQNSHSHQNQHQAQVQQRINAFNAAASQQHQPDYFNNNTARQQPQRIPSGRIDSTRKFIEMEAHNNNGGTSSSPKRSTINYSSSGASSNGNGNVKIGSGNSSTTTITTSTTTHQVTSSSRTVWHLTSSPTSSTKSSSTGGSGEPSHAISNPSYMGLHLNNNNDSIGIGLGGWGNTRFESNRPVSLQPDSISFSRVSAESSSESEAQSISSVSGVKGSKGTKEERRSGMFRIFGRKGDKEKEKDKDKRRSSQVPPQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : : :::*:: * :*::***:**.* * *. :*** :** . :::**::*: : **.*::***: *****:* ******* .*.: . *: *:*:***:****:* .*..*:: **: ** .**.****:*:*****::*. : : .* .** * :::** .*** **: :*** **:**:: *** ::::. :. :*::::: * : : : *: :.::** ** * ::*: :.:*:** ::: : ** :*: ****: :::. *: * :.* *:* *: : * :* :: : * ** .* *. .::. *:: ::*: * :* *: **.:*:: *::.: .: : :: : * :*.: **. * :* : :::**. : *: :: :*: * . *: :* : : :*: : : : *** * :* : *** :.* : *: : :. : .: . : . * . .*: ** ** : .*:.. :: *:*: : . :** : *:***** *:: ::. . : *: : . . : . :: ** * . * :*. * *:::* ** *** :: : . *:*:. : :** :* :: : *:: :: .* :*. . : : . . : .:: . * : : :: * :*: :. **:: *. * * ::: *: : ::: . :.. :: : *:*:.: *: . : : : :: .. .* : : : * ::: * : .* . .* : : . :. : : :*:: .. : ::. :* :: : .* : . ::.: :* : : . : : :.:: ** * : : :* .* :* *:.: * :: . .: :: . . :. .: * . . :. * .::: : :::* :. *.* : ** .*:* *. :** .: .. ::*.:: : : : . ::*: . : : : : :: . *: * ** . ::: : *:::* . .* *: : :: : *: *. : : : *. :: .:: : :. :* * ::* .* *: .* : . ::*.: :: :: *:. *:** *.: * .: ** : *: : : .. : * :. : :: *.. : :*: .:: :.* : *: * ** * . * ** :*** *:.*::.* : :.* *: : . : . :.: . *::* * **. * *: *: :: :: ::: *:* : * : : :** . :: *: :*: :. :: . : :: . : : : *:. * * .* :* **: *:.::: *: .: * . . *.* *: * .* : ::* * :*: *. **..* . . . .: *: :: :* :* :* : : * : :.: *: : * ::::: :.:::.:** . *: *: : .:*.. * . : : *: *. * *: * * .* . * . .:* * : : :: *: : *: : .*: *:*. .:.: : .::: .: ::*::: * :: *: : *: : :: :*: *. * :* :*::*:. *:: * ::: *:.* * * . : . : . : :* ::*:*. * *. : : * : ::.: ** :::. :* :* * ***.*.**: *: : .: . * *:: * : *: : :. : . *: * : :*: **: : ** . : *.**::** :: * * : ** * ::: . *.* :: *. *: :* : . : : :*:.::* .* ::* * *: * .* * * : :::: .: ** . .: : :.: :::: :: : :. : : : :: :*: : :: : :. *: : : : : : * . :* * . : :: *.*:: : : :. *:.* . ::: * ::: * :*. : * :* : *: . .:: * *: ..* * : : .. :* * * * : :: :: *. : :. :: : :* * : : . : * : * : :*: **. *: ** :* .*::*. :. : ::: :: ::**: :. : * :*:.:: .* *.. * ::: : * :* .: * :** * ..* :.* : ::::*: :* :: . *. *..** . ** : : . .: * : : * .::.::. :.*:: * **: ** ** * :* ** ::*: *: :* : ::* * ** ::: : ::* : *: .: .* .: * :::: ***:.:: : . *: : *. :* : * :* : * * : *: *: :*.* * *:. :.:. : *:. :* . :* : : : * . : * : . : . **: : * * : ::. ::: *. *: : : : *:***:*: :: * * * :: : :::: : : : . : :. ** *.. ::.* : * .* ::: ::: * ::*. . : :.* . :.* :: . :: :: :: :* *. * . * . :. * * *. : * ** : :: :::: * :* : . .* . : :: . . :* :*::*:.: : : *: : : *: : : * * : : * * *: * * . *.*: :* *: :::.:* : *:.* * :: : :. : * * : . : . : . .. .. . . . .. ", "identical_positions": 588, "similar_positions": 1125, "identity": "13.41%" }, { "cls_id": "homologset.agr.FB:FBgn0004168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28566-1", "uniprot_id": "5HT1E_HUMAN", "id": "P28566-1", "name": "5-hydroxytryptamine receptor 1E", "aln": "------------------------------------------------------------------------------------------------------------MNITNCT-TEASMAIRPKTITEK-----------------------------------------------------------------------------------------------MLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLF-WRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRS-------------------------------------------------------------------------------------------TDSQNSFAS----CKLTQTFC----------------------------------------------------------------------------------------------------VSDFSTSDPTTEFEK----------------------------------FHAS------IRIPPFDNDLDHPGERQQ---------------------ISSTRERKAARILGLILGAFILSWLPFFIKELIVGLS--IYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30939-1", "uniprot_id": "5HT1F_HUMAN", "id": "P30939-1", "name": "5-hydroxytryptamine receptor 1F", "aln": "------------------------------------------------------------------------------------------------------------MDFLNSSDQNLTSEELLNRMPSK-----------------------------------------------------------------------------------------------ILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLF-WRHQG--TSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASR-IAKEE-------------------------------------------------------------------------------------------VNGQVLLESGEKSTKSVSTSY----------------------------------------------------------------------------------------------------VLEKSLSDPSTDFDK----------------------------------IHST------VRSLRSEFKHEKSWRRQK---------------------ISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCD-KCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28222-1", "uniprot_id": "5HT1B_HUMAN", "id": "P28222-1", "name": "5-hydroxytryptamine receptor 1B", "aln": "---------------------------------------------------------------------------------MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDS-ISLPWK-----------------------------------------------------------------------------------------------VLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFF-WRQAK-AEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLT-------------------------------------------------------------------------------------------RAQLITDSPGSTSSVTSINSR----------------------------------------------------------------------------------------------------VPDVPSES-GSPVYV----------------------------------NQVK------VRVS------DALLEKKK---------------------LMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28221-1", "uniprot_id": "5HT1D_HUMAN", "id": "P28221-1", "name": "5-hydroxytryptamine receptor 1D", "aln": "------------------------------------------------------------------------------------------MSPLNQSAEGLPQE--ASNRSLNATETSEAWDPR-TLQALK-----------------------------------------------------------------------------------------------ISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLF-WRQAK-AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNP-PSLYGKRFT-------------------------------------------------------------------------------------------TAHLITGSAG--SSLCSLNSS----------------------------------------------------------------------------------------------------LHEGHSHSAGSPLFF----------------------------------NHVK------IKLA------DSALERKR---------------------ISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19327-1", "uniprot_id": "5HT1A_RAT", "id": "P19327-1", "name": "5-hydroxytryptamine receptor 1A", "aln": "-----------------------------------------------------------------------------------------------MDVFSFGQGNNTTASQEPFGTGGNVTSISDVTFSYQ-----------------------------------------------------------------------------------------------VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPE-DRSDPDACTISKDHG-YTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAG-------------------------------------------------------------------------------------------TSLGTSSAPPPKKSLNGQPGSGD---------------------------------------------------------------------WRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLP----------------------------------LPSESGSNSYAPACLERKNERNAEAKRK---------------------MALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64264-1", "uniprot_id": "5HT1A_MOUSE", "id": "Q64264-1", "name": "5-hydroxytryptamine receptor 1A", "aln": "-----------------------------------------------------------------------------------------------MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQ-----------------------------------------------------------------------------------------------VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPE-DRSNPNECTISKDHG-YTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAG-------------------------------------------------------------------------------------------TSFGTSSAPPPKKSLNGQPGSGD---------------------------------------------------------------------CRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLP----------------------------------LPSESGATSYVPACLERKNERTAEAKRK---------------------MALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08908-1", "uniprot_id": "5HT1A_HUMAN", "id": "P08908-1", "name": "5-hydroxytryptamine receptor 1A", "aln": "-----------------------------------------------------------------------------------------------MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQ-----------------------------------------------------------------------------------------------VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPE-DRSDPDACTISKDHG-YTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGAD-------------------------------------------------------------------------------------------TRHGASPAPQPKKSVNGESGSRN---------------------------------------------------------------------WRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLP----------------------------------LPSEAGPTPCAPASFERKNERNAEAKRK---------------------MALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28285-1", "uniprot_id": "5HT2A_DROME", "id": "P28285-1", "name": "5-hydroxytryptamine receptor 2A", "aln": "MAHETSFNDALDYIYIANSMNDRAFLIAEPHPEQPNVDGQDQDDAELEELDDMAVTDDGQLEDTNNNNNSKRYYSSGKRRADFIGSLALKPPPTDVNTTTTTAGSPLATAALAAAAASASVAAAAARITAKAAHRALTTKQDATSSPASSPALQLIDMDNNYTNVAVGLGAMLLNDTLLLEGNDSSLFGEMLANRSGQLDLINGTGGLNVTTSKVAEDDFTQLLRMAVTSVLLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISQGWILGPELCDIWTSCDVLCCTASILHLVAIAVDRYWAVTN-IDYIHSRTSNRVFMMIFCVWTAAVIVSLAPQFGWKDPDYLQRIEQQKCMVSQDVSYQVFATCCTFYVPLLVILALYWKIYQTARKRIHRRRPRPVDAAVNNNQPDGGAATDTKLHRLRLRLGRFSTAKSKTGSAVGVSGPASGGRALGLVDGNSTNTVNTVEDTEFSSSNVDSKSRAGVEAPSTSGNQIATVSHLVALAKQQGKSTAKSSAAVNGMAPSGRQEDDGQRPEHGEQEDREELEDQDEQVGPQPTTATSATTAAGTNESEDQCKANGVEVLEDPQLQQQLEQVQQLQKSVKSGGGGGASTSNATTITSISALSPQTPTSQGVGIAAAAAGPMTAKTSTLTSCNQSHPLCGTANESPSTPEPRSRQPTTPQQQPHQQAHQQQQQQQQLSSIANPMQKVNKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFVMALTMPLCA-ACQISDSVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRILFGGHRPVHYRSGKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * : : * *: :: :.*: ****: ***.:*::*: **:*:. * : * :* *:.: : *: ***.***** .**:*** *:*: ::* **. :. :* .* .. :*:.* : *: . : .. :::* :**.* ::: ** :*: *: . : . . . ::: : ****:. *.:* *:*::.*****: * : .. . : :: **** ** :**::*: . :*: **:::: ", "identical_positions": 78, "similar_positions": 97, "identity": "9.33%" }, { "cls_id": "homologset.agr.FB:FBgn0004169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNB2-1", "uniprot_id": "TNNT1_RAT", "id": "Q7TNB2-1", "name": "Troponin T, slow skeletal muscle", "aln": "MSD----------TEE--QEYEEEQAEDEEAV-EEEAPEE-----------------PEPVAEREEE----------------------RPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKD--LLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQR---FRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMG------------AHFGGYLVK---AEQKRG-KRQTGREMKLRILSERKKPLNIDYMGEDQLR----------------EKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKG---AGKGRVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88346-1", "uniprot_id": "TNNT1_MOUSE", "id": "O88346-1", "name": "Troponin T, slow skeletal muscle", "aln": "MSD----------TEE--QEYEEEQAEDEEAVEEEEAPEE-----------------PEPVAEREEE----------------------RPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKD--LLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQR---FRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMG------------AHFGGYLVK---AEQKRG-KRQTGREMKLRILSERKKPLNIDYMGEDQLR----------------EKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKG---AGKGRVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13805-1", "uniprot_id": "TNNT1_HUMAN", "id": "P13805-1", "name": "Troponin T, slow skeletal muscle", "aln": "MSD----------TEE--QEYEEEQPEEEAAEEEEEAPEE-----------------PEPVAEPEEE----------------------RPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKD--LLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQR---FRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMG------------AHFGGYLVK---AEQKRG-KRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKG---AGKGRVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50753-1", "uniprot_id": "TNNT2_RAT", "id": "P50753-1", "name": "Troponin T, cardiac muscle", "aln": "MSD----------AEEEVVEYEEEQEEEDWSEEEEDEQEEAVEEE-----DGEAEPDPEGEAEAEEDKAEEVGPDEEARDAEDGPVEDSKPKPSRLFMPNLVPPKIPDGERVDFDDIHRKRMEKD--LNELQTLIEAHFENRKKEEEELISLKDRIEKRRAERAEQQR---IRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-------------MHFGGYIQK-AQTERKSG-KRQTEREKKKKILAERRKVLAIDHLNEDQLR----------------EKAKELWQSIHNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT---RGKAKVTGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50752-1", "uniprot_id": "TNNT2_MOUSE", "id": "P50752-1", "name": "Troponin T, cardiac muscle", "aln": "MSD----------AEEVVEEYEEEQEEEDWSEEEEDEQEEAVEEEE----AGGAEPEPEGEAETEEANVEEVGPDEEAKDAEEGPVEDTKPKPSRLFMPNLVPPKIPDGERVDFDDIHRKRVEKD--LNELQTLIEAHFENRKKEEEELISLKDRIEKRRAERAEQQR---IRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-------------MHFGGYIQKQAQTERKSG-KRQTEREKKKKILAERRKALAIDHLNEDQLR----------------EKAKELWQSIHNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT---RGKAKVTGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45379-1", "uniprot_id": "TNNT2_HUMAN", "id": "P45379-1", "name": "Troponin T, cardiac muscle", "aln": "MSD----------IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQE------EAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKD--LNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQR---IRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-------------MHFGGYIQKQAQTERKSG-KRQTEREKKKKILAERRKVLAIDHLNEDQLR----------------EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT---RGKAKVTGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TTC6-1", "uniprot_id": "A0AB32TTC6_DANRE", "id": "A0AB32TTC6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------MEKD--LTELQTLIEAHFEKRKKEEEELINLTQRIENRRSERAEQQR---IRTERDRERQNKLAEEKARKEEEEAKRKADDDAKKKKVLTSF--------------QYTGYMQR---TEKRGGPKKQTEREKKKTILSERRKELNIENIGADKLR----------------ETANELWKKMRQLEAEKFEMHYKYMSQKYEITVLRNRVSDHQKNTK-----GSRSKRGLRK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09739-1", "uniprot_id": "TNNT3_RAT", "id": "P09739-1", "name": "Troponin T, fast skeletal muscle", "aln": "MSD------EETEQVEEQYEEEEEA-QEE--EVQEEAPEPE---------------------EVQE-----------------------EEKPRPK----LTAPKIPEGEKVDFDDIQKKRQNKD--LMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQR---IRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMG------------ANYSSYLAK---ADQKRG-KKQTAREMKKKILAERRKPLNIDHLSDDKLR----------------DKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ47-1", "uniprot_id": "TNNT3_MOUSE", "id": "Q9QZ47-1", "name": "Troponin T, fast skeletal muscle", "aln": "MSD------EETEQVEEQYEEEEEA-QEE--EVQEEAPEPE---------------------EVQEDAVAEEEREE----------DEEEEKPRPK----LTAPKIPEGEKVDFDDIQKKRQNKD--LMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQR---IRAEKEREPQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMG------------ANYSSYLAK---ADQKRG-KKQTAREMKKKILAERRKPLNIDHLSDDKLR----------------DKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45378-1", "uniprot_id": "TNNT3_HUMAN", "id": "P45378-1", "name": "Troponin T, fast skeletal muscle", "aln": "MSD------EEVEQVEEQYEEEEEA-QEEAAEVHEEVHEPE---------------------EVQEDT-----AEE----------DAEEEKPRPK----LTAPKIPEGEKVDFDDIQKKRQNKD--LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQR---IRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMG------------ANYSSYLAK---ADQKRG-KKQTAREMKKKILAERRKPLNIDHLGEDKLR----------------DKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUE0-1", "uniprot_id": "A0AB32TUE0_DANRE", "id": "A0AB32TUE0-1", "name": "", "aln": "MSDTEDVGVEEVVEVEVAPEAAPEP-EPEPEPEQEPVPEPEPEPEPEPEKQPEPEPEPEPEQEVHEEEAYEEEVDEG---------EQDEEKPKFK----PSAPKIPDGDKVDFDDIQKKRQNKD--LVELQALIDAHFEHRKKEEEELIALKDRIEKRRSERAEQQR---IRAEKDKERQARREEERLRKEEADAKKRADEDAKKKSALSNMG------------SQYSSYLQK---ADSKRGGKKQTEREKKKKILAERRKPLNIDHMNEDKLR----------------EKAKELWDWLYSLEAEKFEHMEKLKRQKYEVTTQRKRVEELSKYSKKGAAARRRK------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TLE9-1", "uniprot_id": "A0AB32TLE9_DANRE", "id": "A0AB32TLE9-1", "name": "", "aln": "MYS---ITIINCIHIHNFSSIVPPPTEEEPAPEVEEPPEVE---------------------EEPEPEPQEAPVAEE---------VTDETKPKPKFMPNISAPKIPEGDKVDFDDIHRKRQEKD--LSELQSLIEAHFIQRKKDEEELIALVNRIEKRRGERAEQQR---IRAEKEKERQARLAEEKERREQEEQRKKHDEDAKKKKALTNMT------------HQYGGIQQK---GDGRKGAKKQTEREKKKKILAERKKPLNIDHLSEDKLK----------------EKASEMWQWMMQLEAEKFDLSEKLKRQKYDMNVLQTRINEQQKFAK---GRGKGKVGGRLR------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19351-1", "uniprot_id": "TNNT_DROME", "id": "P19351-1", "name": "Troponin T, skeletal muscle", "aln": "MSD------------------DEEYTSSEEEEVVEETREET------------------------------------------------------------KPPQTPAEGEGDPEFIKRQDQKRSDLDDQLKEYITEWRKQRSKEEDELKKLKEKQAKRKVTRAEEEQKMAQRKKEEEERRVREAEEKKQREIEEKRMRLEEAEKKRQAMLQAMKDKDKKGPNFTIAKKDAGVLGLSSAAMERNKTKEQLEEEKKISLSFRIKPLAIEGFGEAKLR----------------EKAQELWELIVKLETEKYDLEERQKRQDYDLKELKERQKQQLRHKALKKGLDPEALTGKYPPKIQVASKYERRVDTRSYDDKKKLFEGGWDEISKDSNEKIWNEKKEQYTGRQKSKLPKWFGERPGKKAGEPETPEGEEDAKADEDIVEDDEEVEEEVVEEEDEEAEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. :*: * *.*:*:** * :: .*: ***::: * :.:.* : : **: ::* : : : :: :*:..: . : . . . .:: .* * *: * * * *: :. :*: :.*.*: . : .** :*:: : *.*::. * .. : ", "identical_positions": 34, "similar_positions": 67, "identity": "6.92%" }, { "cls_id": "homologset.agr.FB:FBgn0004170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M7F4-1", "uniprot_id": "A0ABK0M7F4_RAT", "id": "A0ABK0M7F4-1", "name": "", "aln": "----------------------------MEKCKSAGLLALH---SPLRASPLG-----A------LARREPCRVS-----ARQDTA-------DCARRRPCPSLPP--------GGVAEPAFLRQRNERERQRVRCVNEGYARLRQHLPR-----------ELAGQRLSKVETLRAAIGYIKQLQELLER----------------------------HRPDLNSD---------------------------------------------------------GESKASSGASPCSS-----------EPEERG-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QW46-1", "uniprot_id": "M0QW46_MOUSE", "id": "M0QW46-1", "name": "", "aln": "----------------------------MEKRRSAGLLALP---SALRTAPLG-----A------LPGREPCRVS-----VRQDAA-------DCARRRPYSSLPL--------GGVAEPAFLRQRNERERQRVRCVNEGYARLRQHLPR-----------ELAGQRLSKVETLRAAISYIKQLQELLER----------------------------HRPDCNSD---------------------------------------------------------GESKASSGASPCS------------ESEERS-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XD76-1", "uniprot_id": "ASCL4_HUMAN", "id": "Q6XD76-1", "name": "Achaete-scute homolog 4", "aln": "----------------------------METRKPAERLALP---YSLRTAPLG-----VPGTLPGLPRRDPLRVA-----LRLDAACWEWARSGCARGWQYLPVPL--------DSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPR-----------ELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAG--------------AVPQRRAECNSD---------------------------------------------------------GESKASSAPSPSS------------EPEEGGS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LUI6-1", "uniprot_id": "F1LUI6_RAT", "id": "F1LUI6-1", "name": "", "aln": "----------------------------MNSNFCRALVDR----GSPGGIQLG---VVAPAGPTPLAATEPLGN---VPFLLYPGHSEPSYYDAYTGVFPYVPFPGAFGVY---DYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPG-----------ALAEKRLSKVETLRAAIRYIKYLQELLSAAPDGAP---PTAT--------------SPPPAHAGH---------------------------------------------------------GNALQPPSLVAESS-GSSFSPSPFLESEEPSL----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0QWB7-1", "uniprot_id": "ASCL5_MOUSE", "id": "M0QWB7-1", "name": "Achaete-scute homolog 5", "aln": "----------------------------MNSNFCRALVDR----GPPGGMQLG---VVAPAGQTPLAATEPLSN---VPFLLYPGHSEPPYYDAYTGVFPYVPFPGAFGVY---DYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPG-----------ALTEKRLSKVETLRAAIRYIKYLQELLSATPDGAP---PPAT--------------SPPPAHTGH---------------------------------------------------------SNVPQPSSLVAESS-GSPFSSSPFLESEEPSL----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU5-1", "uniprot_id": "ASCL5_HUMAN", "id": "Q7RTU5-1", "name": "Achaete-scute homolog 5", "aln": "----------------------------MNNNFCRALVDRR-PLGPPSCMQLG---VMPPPRQAPLPPAEPLGN---VPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFGVY---EYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPG-----------ALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGST---PPASRGLPGTGPCPAPPATPRPDRPGD---------------------------------------------------------GEARAPSSLVPESSESSCFSPSPFLESEESWH----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJR7-1", "uniprot_id": "ASCL3_MOUSE", "id": "Q9JJR7-1", "name": "Achaete-scute homolog 3", "aln": "----------------------------MDTRSYPSPPDRLSVFAESAHLPLSRPFYLDPMVTVHLCPETPVPASYTDELPLLPFSSDTLIMNNYGDPYP-FPFPMPYTNYRRCDYTYGPAFIRKRNERERQRVKCVNEGYARLRRHLPE-----------DYLEKRLSKVETLRAAIKYISYLQSLLY--PDESE---TKKN---------------PRTASCG------------------------------------------------------------SLDPALRVI-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19360-1", "uniprot_id": "ASCL2_RAT", "id": "P19360-1", "name": "Achaete-scute homolog 2", "aln": "MESHFNWYGVPRLQKASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCGAPKPVAGAPALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPELLRCSRRR---RSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPH-----------GGANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALSGGLLTPATRPSDVCTQPSASPASASLSCTSTSP------------------------------------------------DRLGCSEPASPRSAYSSEDSSCEGETYPMG-QMFDFSNWLGGY--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35885-1", "uniprot_id": "ASCL2_MOUSE", "id": "O35885-1", "name": "Achaete-scute homolog 2", "aln": "MEAHLDWYGVPGLQEASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDGGALPRLMPTSSGVAGACAARRRQASPELLRCSRRR---RSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPH-----------GGANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALAGGLLTPATPPSDECAQPSASPASASLSCASTSPS----------------------------------------------PDRLGCSEPTSPRSAYSSEESSCEGELSPMEQELLDFSSWLGGY--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19359-1", "uniprot_id": "ASCL1_RAT", "id": "P19359-1", "name": "Achaete-scute homolog 1", "aln": "MESSGKMESG----AGQQPQPP--QPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQAPQQQAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPN-----------GAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPN----------YSNDLN-----------------------------------------------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02067-1", "uniprot_id": "ASCL1_MOUSE", "id": "Q02067-1", "name": "Achaete-scute homolog 1", "aln": "MESSGKMESG----AGQQPQPP--QPFLPPAACFFAT-AAAAAAAAAAAAQSAQQQQPQ-APPQQAPQLSPVADSQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPN-----------GAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPN----------YSNDLN-----------------------------------------------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50553-1", "uniprot_id": "ASCL1_HUMAN", "id": "P50553-1", "name": "Achaete-scute homolog 1", "aln": "MESSAKMESGG---AGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPN-----------GAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPN----------YSNDLN-----------------------------------------------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90259-1", "uniprot_id": "ASL1A_DANRE", "id": "Q90259-1", "name": "Achaete-scute homolog 1a", "aln": "MDITAKMEIS----VNQQ-------QFMPP-ACFFAS---------------------------QSIQLSP-TDSQCS---NKSASKQAKRQRSSSPELLRCKRRLNFAGFGYSLPQQQPHAVARRNERERNRVKLVNNGFATLREHVPN-----------GAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISQN----------YSNDMN-----------------------------------------------------------SMAGSPVSSYSSDEGSYD-PLSPEEQELLDFTNWF-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10084-1", "uniprot_id": "AST4_DROME", "id": "P10084-1", "name": "Achaete-scute complex protein T4", "aln": "----------------------MKNNNNTTKSTTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSSSGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVPQQISTHLDRLDHLDNELHTHSQLQLKFEPYEHFQLDEEDCTPDDEEILDYISLWQEQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :** ***:**: ** .: ** *:* :::***:*** *: ** ** *: . ", "identical_positions": 25, "similar_positions": 15, "identity": "6.81%" }, { "cls_id": "homologset.agr.FB:FBgn0004177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63330-1", "uniprot_id": "PP2AA_MOUSE", "id": "P63330-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63331-1", "uniprot_id": "PP2AA_RAT", "id": "P63331-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JYA4-1", "uniprot_id": "A0A0G2JYA4_RAT", "id": "A0A0G2JYA4-1", "name": "Serine/threonine-protein phosphatase", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPTIDTLDHIGALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67775-1", "uniprot_id": "PP2AA_HUMAN", "id": "P67775-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKVFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFZ9-1", "uniprot_id": "A0A8M1PFZ9_DANRE", "id": "A0A8M1PFZ9-1", "name": "Serine/threonine-protein phosphatase", "aln": "----------------------------------------------------------MEEKAFAK----------ELDQWIEQLNECKQLSETQVKTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62715-1", "uniprot_id": "PP2AB_MOUSE", "id": "P62715-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62714-1", "uniprot_id": "PP2AB_HUMAN", "id": "P62714-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62716-1", "uniprot_id": "PP2AB_RAT", "id": "P62716-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23696-1", "uniprot_id": "PP2A_DROME", "id": "P23696-1", "name": "Serine/threonine-protein phosphatase PP2A", "aln": "----------------------------------------------------------MEDKATTK----------DLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23594-1", "uniprot_id": "PP2A1_YEAST", "id": "P23594-1", "name": "Serine/threonine-protein phosphatase PP2A-1 catalytic subunit", "aln": "MDTDLDVPMQDAVTEQLTPTVSEDMDLNN--------NSSDNNAEEFSVDDLKPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23595-1", "uniprot_id": "PP2A2_YEAST", "id": "P23595-1", "name": "Serine/threonine-protein phosphatase PP2A-2 catalytic subunit", "aln": "MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTDEELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :* :****:*:*.:*: *.* :* **. * ::* *.**: :. ***:***********:***:*** .**********************: ***:**** .*:***************************.***** *******:*:*****.:********** *:::*:: *:*:*******************************:*****:** **::*.*:*::********** *.*::********************:**:*:. : .***:**: * *** *:*:******", "identical_positions": 222, "similar_positions": 60, "identity": "58.89%" }, { "cls_id": "homologset.agr.FB:FBgn0004179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD82-1", "uniprot_id": "DNJ5B_RAT", "id": "D3ZD82-1", "name": "DnaJ homolog subfamily C member 5B", "aln": "MACNIPNQRQRAMSTSGESLYEILGLHKGASCEEIKKTY----------------RKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDNSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCCLCCCCNCCCGHCRPKTSTPEE-EFYVS-----------------PEDLEEQIRTDM--------------EKDMDFPVVLQP---------------TNTNEK---------TQLIREG-SRSYCTDS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ94-1", "uniprot_id": "DNJ5B_MOUSE", "id": "Q9CQ94-1", "name": "DnaJ homolog subfamily C member 5B", "aln": "MACNAPNQRQRTLSTSGESLYEILGLHKGASCEEIKKTY----------------RKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCCLCCCCNCCCGHCRPKSSTPEE-EFYVS-----------------PEDLEEQIRTDM--------------EKDMDFPVVLQP---------------TNTNEK---------TQLIREG-SRSYCTDS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UF47-1", "uniprot_id": "DNJ5B_HUMAN", "id": "Q9UF47-1", "name": "DnaJ homolog subfamily C member 5B", "aln": "MACNIPNQRQRTLSTTGEALYEILGLHKGASNEEIKKTY----------------RKLALKHHPDKNPDDPAATEKFKEINNAHAILTDISKRSIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKALFVIVGLLTGCYFCCCLCCCCNCCCGHCRPESSVPEE-DFYVS-----------------PEDLEEQIKSDM--------------EKDVDFPVFLQP---------------TNANEK---------TQLIKEG-SRSYCTDS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60905-1", "uniprot_id": "DNJC5_RAT", "id": "P60905-1", "name": "DnaJ homolog subfamily C member 5", "aln": "MADQ----RQRSLSTSGESLYHVLGLDKNATSDDIKKSY----------------RKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVVCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVS-----------------PEDLEAQLQSDE--------------REATDTPIVIQP---------------ASATET---------TQLTADS-HPSYHTDGFN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60904-1", "uniprot_id": "DNJC5_MOUSE", "id": "P60904-1", "name": "DnaJ homolog subfamily C member 5", "aln": "MADQ----RQRSLSTSGESLYHVLGLDKNATSDDIKKSY----------------RKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVVCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVS-----------------PEDLEAQLQSDE--------------REATDTPIVIQP---------------ASATET---------TQLTADS-HPSYHTDGFN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3Z4-1", "uniprot_id": "DNJC5_HUMAN", "id": "Q9H3Z4-1", "name": "DnaJ homolog subfamily C member 5", "aln": "MADQ----RQRSLSTSGESLYHVLGLDKNATSDDIKKSY----------------RKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVS-----------------PEDLEAQLQSDE--------------REATDTPIVIQP---------------ASATET---------TQLTADS-HPSYHTDGFN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF34-1", "uniprot_id": "E7FF34_DANRE", "id": "E7FF34-1", "name": "DnaJ homolog subfamily C member 5", "aln": "MAEQQ---RQRALSTSGESLYVVLGVEKNTAQEDIKKSY----------------RKLALKFHPDKNPNNPEAADKFKEINNAHAILSDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGVATGCYFCCCLCCCCNCCCGKCKPHPPHSDDPDFYVS-----------------PEDLEAQMQSDE--------------RDGS-SPIMMQP---------------SSATES---------TQLTADSHHTSYRTDANY------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F596-1", "uniprot_id": "E7F596_DANRE", "id": "E7F596-1", "name": "DnaJ homolog subfamily C member 5B", "aln": "MAEQ----RQRALSTSGEALYQVLGLDKNCTHDDIKRSY----------------RKLALKYHPDKNPENPDATDKFKELNNAHAVLSDVTKRNIYDKYGSLGLYVSQQFGEENVNTYFMLSSWWAKGLFAICGLLTGCYFCCCLCCCFNCCCGKCKPHTPGEEDPEVYVS-----------------PEDLEEQIRTDN--------------ERDGDTPIVLQP---------------TNASEK---------TQLIGDG-HRSYT-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03751-1", "uniprot_id": "DNJC5_DROME", "id": "Q03751-1", "name": "DnaJ homolog subfamily C member 5 homolog", "aln": "MSAPG--MDKRKLSTSGDSLYEILGLPKTATGDDIKKTY----------------RKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITGCCCCCCCCCCCNFCCGKFKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDDVNLGAGGAPVTSQPREQAGGQPVFAMPPPSGAVGVNPFTGAPVAANEN---------TSLNTTE-QTTYTPDMVNQKY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2B4Z2-1", "uniprot_id": "A0A8M2B4Z2_DANRE", "id": "A0A8M2B4Z2-1", "name": "", "aln": "MTETS--RPQRKLSRAGESLYQTLGLQKGASSEDIKKAY----------------RKLALKHHPDKNPNNPEAAEKFKEINNANSILNDETKRQIYDEYGSMGLYIADQFGEDSVKYYFLMSKCWFKTLLCIGTILT----CCCCCCCCCFCCGKCG--GSEPPDNFQYVD-----------------PEELAEEEERSR----------------DNETVIIGQPIP-----------SPAPAADSGYPVIVGMPIPLSADGDTASLIPPDTHVEVIKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N7S2-1", "uniprot_id": "DNJ5G_HUMAN", "id": "Q8N7S2-1", "name": "DnaJ homolog subfamily C member 5G", "aln": "MSTVK--EAAHRLSKSEMSLYAVLDLKKGASPEDFKKSYSHSALLPHPPFEYHLGRKLALRYHPDKNPGNAQAAEIFKEINAAHAILSDSKKRKIYDQHGSLGIYLYDHFGEEGVRYYFILNSCWFKTLVILCTLLT----CCCFCCCCCFCCGALKPPPEQDSGRKYQQN-----------------VQSQPPRSGAK--------------------CDFRSEE----------------NSEDD----------F----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZKL6-1", "uniprot_id": "A0A8I5ZKL6_RAT", "id": "A0A8I5ZKL6-1", "name": "", "aln": "MPRAY--EATQRLSKDGKSLYAVLELKKGAQPEEIKKAY----------------RKLALQYHPDKNPGNSQAAEFFKDINAAHAVLTDPTKKKIYDRHGSLGLYLYDHFGEEGVRTYFIVNSCWFKTLVILCCLLT----GCCCCCCCCLCCGRLNPSAEEEN-ENYQVN-----------------VSSQPSRSSEEQ----------------RQGLEVLAQR----------------ESLDT----------QPIGYIEERSR------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :* :** * : * :::*::* *****:.****** : *:: **::* *:::*.* .*:.***.:**:*:*: ::**::.*. **::.. * :. : * ** *** *** . . . : : ", "identical_positions": 49, "similar_positions": 47, "identity": "17.5%" }, { "cls_id": "homologset.agr.FB:FBgn0004197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97607-1", "uniprot_id": "JAG2_RAT", "id": "P97607-1", "name": "Protein jagged-2", "aln": "------------------------------------------------------------------------------------------------------GACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGP---CSYGYGATPVLGSNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPD--EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCV-EPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSCHEVLSG--------------------------------------------------------------FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG--------------------------------------------KPCLNAFSCKNLIGGYYCDCLPGWKGANCHININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYYKCASSPCRRGGICEDLVDGFRCHCPRGLSGPLCEVDVDLWCEPNPCLNGARCYNLEDDYYCACPEDFGGKNCSVPRETCPGGACRVIDGCGFEAGSRAHGAAP----SGVCGPHGHCVSL--PGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFACFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCVCDDGWKDKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRG------------------VSFPHGSSWVEDCNSCRCLDGHRDCSKVWCGWKPCLLSPQP---SALSAQCPPGQQCREKAMGQCLQPPCENWGECTAEDPLPPSTP--------CLPRTTHLDNNCARLTLHFNRDQVPQGTTVGAICSGIRALPATRAAARDR--------LLLLLCDRASSGASAVEVAVSFSPARDLPDSSLIQST-----------AHAIVAAITQR-GNSSLLLAVTEVKVETVVMGGSSTGLLVPVLCSVFSVLWLACMVICVWWTRKRRKERERSRL----------PRDESANNQWA-PLNPIRNPIERPGSSGLGTGGHKDVLYQCKNFTPPPRRAGEALPGPASHGAGGEDEEDEELSRGDGRLSRSREVPLTQIHQRPQLLPGKASLLAPGPKVDNRAVRSTK------------DVRCAGRE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYE5-1", "uniprot_id": "JAG2_MOUSE", "id": "Q9QYE5-1", "name": "Protein jagged-2", "aln": "--------------------------------------------------------MRARGWGRLPRRLLLLLVLCVQATRPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGP---CSYGYGATPVLGGNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPD--EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCV-EPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSCHEVPSG--------------------------------------------------------------FECHCPSGWNGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG--------------------------------------------KPCLNAFSCKNLIGGYYCDCLPGWKGINCQININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYDKCASSPCRRGGICEDLVDGFRCHCPRGLSGLHCEVDMDL-CEPSPCLNGARCYNLEGDYYCACPEDFGGKNCSVPRDTCPGGACRVIDGCGFEAGSRARGVAP----SGICGPHGHCVSL--PGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFRCFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRG------------------MSFPHGSSWMEDCNSCRCLDGHRDCSKVWCGWKPCLLSGQP---SDPSAQCPPGQQCQEKAVGQCLQPPCENWGECTAEEPLPPSTP--------CQPRSSHLDNNCARLTLRFNRDQVPQGTTVGAICSGIRALPATRAAAHDR--------LLLLLCDRASSGASAVEVAVSFSPARDLPDSSLIQST-----------AHAIVAAITQR-GNSSLLLAVTEVKVETVVMGGSSTGLLVPVLCSVFSVLWLACVVICVWWTRKRRKERERSRL----------PRDESANNQWA-PLNPIRNPIERPGGSGLGTGGHKDILYQCKNFTPPPRRAGEALPGPAGHGAGGEDEEDEELSRGDGDSPEAEKFISHKFTKDPSCSLGRPARWAPGPKVDNRAVRSTK------------DVRRAGRE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y219-1", "uniprot_id": "JAG2_HUMAN", "id": "Q9Y219-1", "name": "Protein jagged-2", "aln": "--------------------------------------------------------MRAQGRGRLPRRLLLLLALWVQAARPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP---CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPN--EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCV-EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSG--------------------------------------------------------------FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG--------------------------------------------KPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDL-CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA----SGVCGPHGRCVSQ--PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRG------------------TPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQP---EALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEE--PPSTP--------CLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAICSGIRSLPATRAVARDR--------LLVLLCDRASSGASAVEVAVSFSPARDLPDSSLIQGA-----------AHAIVAAITQR-GNSSLLLAVTEVKVETVVTGGSSTGLLVPVLCGAFSVLWLACVVLCVWWTRKRRKERERSRL----------PREESANNQWA-PLNPIRNPIERPG-------GHKDVLYQCKNFTPPPRRADEALPGPAGHAAVREDEEDEDLGRGEEDSLEAEKFLSHKFTKDPGRSPGRPAHWASGPKVDNRAVRSIN------------EARYAGKE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDN4-1", "uniprot_id": "A0A8N7TDN4_DANRE", "id": "A0A8N7TDN4-1", "name": "Delta-like protein", "aln": "---------------------------------------------------------MHNYFGACFSIVFLILTFWTEVCQSSGYLELQLISVENDRAELANGNCCDG----ARDGLCDQDQCDTYLKVCLKEYQVEVTTSGF---CTYGTGSSSVVGGNTFQLK--GFNGNPNKAN-------DLGTVIIPFQFAWPRAYTLIVEAWDWDNQTITESSDDQLIMRSVNRGEMNPGEERQVIQHKGRTASIQYSVRVRCDRHYYGNKCNKQCRPRDDYFGHYTCDQSGNQQCMEGWTGQDCKQAICKQGCSELHGSCETPGDCVCKYGWQGPLCDECLPYPGCKHGTCV-KPWTCTCEKNWGGLLCDKDLNYCGTHSPCVNGGTCLNTEPDEYFCLCPEGYSGENCHISKHACMSNPCANGGTCHELASG--------------------------------------------------------------FECLCPPGWDGPTCAKDKDECESNPCSYGGTCIDLENGFECLCLPQWTGKTCQIDVNECTR--------------------------------------------RPCLNAYACKNLIGGYHCNCYPGWAGPNCNININSCYGQCQNGGTCQDGRHGYVCQCQPGFMGRHCEVQQSRCASSPCQNGGRCRSLATGYECECLYGYTGNNCEVQVDL-CNPNPCQKKAQCHSLQGDFYCACADEYEGKTCSQLRDHCKTSTCHVIDSCTTAITTNGTEKAVRYILSNVCGPHGRCISQ--SGGNFTCACQPGFSGTYCHENINDCESSPCHSGGTCIDDIDSFRCVCPDGFDGQLCELEVNECSSDPCLNGGHCIDLLNDFYCRCTDNWKGKTCNSRENQCDSSTCANGGTCHDRGESFRCLCPSGWGGSTCNTAMNSSCESGPCLNGGTCIGSGSVFKCICKDGWEGPTCAQNVDDCNPHPCYNGGQCVDGVNWFRCECAPGFAGPDCRINIDECQSSPCSYGATCVDEINGYRCLCPMGRAGPRCQDFIGVGKACDRSG------------------LQVHHGGRWEDGCNSCQCMNGNIKCTKVNCGHQSCLLQSDSE--VAQRPLCPLGQECVEHHFLSCLRPPCDQLGMCSTRGRLQPINTR-------CLPNNGYLDVNCARVTLVFDSDTVPQGTTAEGVCTELTYLPITRTLAKDH--------ALFLLCDQSPSGHNAVEVAMSYEQNNFVDGPAQIHDV-----------VRSIIDVLSKP-HNSTLLLAVREVRVDTQDP-HPQVGYLIPLLCVLFVVLWISCIIVCVWWFRRRRKARQREDT----------QMEESINNQRG-TLLSARTPH----------KDNTDPMQENKNLLYPLDRVGDGAEREEEEEEGDEESNRGLALHKCSSLAYSKGDTVYVIHTSAQNQQHRTHYGGKDNRCKNNVNERLS------------EHTKDHYV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63722-1", "uniprot_id": "JAG1_RAT", "id": "Q63722-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRPGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-ARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGP---CSFGSGSTPVIGGNTFNLK---ASRGNDRNR-----------IVLPFSFAWPRSYTLLVEAWDSSNDTIQ---PDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDY-CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSE--SGGKFTCDCNKGFTGTYCHENINDCEGNPCTNGGTCIDGVNSYKCICSDGWEGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYQCICPPGHSGAKCHEVS--GRSCITMG------------------RVILDGAKWDDDCNTCQCLNGRVACSKVWCGPRPCR-LHKG------HGECPNGQSCIPVLDDQCFVRPCTGAGECRSSSLQPVKTK---------CTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEY--------SIYIACEPSLSANNEIHVAISAEDI--RDDGNPVKEI-----------TDKIIDLVSKRDGNSSLIAAVAEVRVQRR-PLKNRTDFLVPLLSSVLTVAWVCCLVTAFYWCVRKRRRKPSSHT-------HSAPEDNTTNNVRE-QLNQIKNPIEKHGAN---TVPIK--DYENKNSKMSKIRT---------HNSEVEEDDMDKHQQKVRFAKQPVYTLVDREEKVPQR--TPTKHPNWTNKQDNRDLESAQ------------SLNRMEYIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXX0-1", "uniprot_id": "JAG1_MOUSE", "id": "Q9QXX0-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRPGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-VRNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGP---CSFGSGSTPVIGGNTFNLK---ASRGNDRNR-----------IVLPFSFAWPRSYTLLVEAWDSSNDTIQ---PDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDY-CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ--SGGKFTCDCNKGFTGTYCHENINDCESNPCKNGGTCIDGVNSYKCICSDGWEGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYQCICPPGHSGAKCHEVS--GRSCITMG------------------RVILDGAKWDDDCNTCQCLNGRVACSKVWCGPRPCR-LHKS------HNECPSGQSCIPVLDDQCFVRPCTGVGECRSSSLQPVKTK---------CTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEY--------SIYIACEPSLSANNEIHVAISAEDI--RDDGNPVKEI-----------TDKIIDLVSKRDGNSSLIAAVAEVRVQRR-PLKNRTDFLVPLLSSVLTVAWVCCLVTAFYWCVRKRR-KPSSHT-------HSAPEDNTTNNVRE-QLNQIKNPIEKHGAN---TVPIK--DYENKNSKMSKIRT---------HNSEVEEDDMDKHQQKVRFAKQPVYTLVDREEKAPSG--TPTKHPNWTNKQDNRDLESAQ------------SLNRMEYIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78504-1", "uniprot_id": "JAG1_HUMAN", "id": "P78504-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-ARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGP---CSFGSGSTPVIGGNTFNLK---ASRGNDRNR-----------IVLPFSFAWPRSYTLLVEAWDSSNDTVQ---PDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDY-CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQ--SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVS--GRPCITMG------------------SVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCL-LHKG------HSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTK---------CTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEY--------SIYIACEPSPSANNEIHVAISAEDI--RDDGNPIKEI-----------TDKIIDLVSKRDGNSSLIAAVAEVRVQRR-PLKNRTDFLVPLLSSVLTVAWICCLVTAFYWCLRKRR-KPGSHT-------HSASEDNTTNNVRE-QLNQIKNPIEKHGAN---TVPIK--DYENKNSKMSKIRT---------HNSEVEEDDMDKHQQKARFAKQPAYTLVDREEKPPNG--TPTKHPNWTNKQDNRDLESAQ------------SLNRMEYIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Y54-1", "uniprot_id": "JAG1B_DANRE", "id": "Q90Y54-1", "name": "Protein jagged-1b", "aln": "---------------------------------------------------MILRRS---SVFSAFYLHAFLLCLRTTVSDASGHFELEILSMQNANGELQNGACCDG-ARNPADRKCTRDECDTYFKVCLKEYQSRVSSAGA---CSFGTGSTPVLGGNKFSTK---GTR-SEKSR-----------IVLPFSFAWPRSYTLIVEALDFNNETASE--SGKLIEKAYHSGMINPNRQWQRLTHNGPVAQFEYQIRVTCLEHYYGFGCNKFCRPRDEFFGHYTCDQNGNKTCLEGWTGPDCNTAICRQGCSTEHGSCKQPGGCKCLYGWQGPYCDKCIPHPGCVHGTCV-EPWQCLCDTNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCEDGYSGVNCERAEHACLSNPCANGGTCKETSQG--------------------------------------------------------------YECHCAIGWSGTSCEINVDDCTPNQCKHGGTCQDLVNGFKCACPPHWTGKTCQIDANECED--------------------------------------------KPCVNAKSCHNLIGAYFCECLPGWSGQNCDININDCKGQCLNGGTCKDLVNGYRCLCPPGYTGEQCEKDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDY-CKPNPCQNGAQCFNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDSCTVAVASNSTPEGVRYISSNVCGPHGRCRSQ--AGGQFTCECQEGFRGTYCHENINDCESNPCRNGGTCIDKVNVYQCICADGWEGVHCEINIDDCSLNPCLNKGACQDLVNDFYCECRNGWKGKTCHSRDSQCDEATCNNGGTCHDEGDTFKCRCSPGWEGATCNIAKNSSCLPNPCENGGTCVVNGDSFNCVCKEGWEGSTCTENTNDCNPHPCYNSGTCVDGENWYRCECAPGFAGPDCRININECQSSPCAFGSTCVDEINGYRCLCPPGRIGPDCQEVV--GRPCIANG------------------QVTADGAKWEEDCNICQCQNGRIHCTMMWCGPKSCR-IGKA------RGGCPASQSCVPIKEEQCFVKPCPSLGECWPSAPPPPSKC---------HASFSYQDDSCANITFTFNKENMPQGLSVEHVCNELRHWYLLKNLSTEY--------AVSISCEPSSSASNEIHISISTEEP--RTDRSPIKDI-----------TVQIIDLVSKHNGNSTIIKAITGVRVHQI-PSP-KTDYLVPLLSSIFIVLWIFALASAFLWCIHRRR-KQNTHSNT----ATSATEDNTTNNVRE-QLNQIKNPIEKHAAH---GVPIK--DYEGKNSIIAKIRT---------HNSEVEEEDMDKHLQKARFTKQPAYTLVEREERAPN------KNPNWTNKQDNRDLETAQ------------SLNRMEYIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90Y57-1", "uniprot_id": "JAG1A_DANRE", "id": "Q90Y57-1", "name": "Protein jagged-1a", "aln": "---------------------------------------------------MILRPS---ATFAALSAHVLLRCLWMRVCEASGHFEMQVLSMQNVNGELQSGACCDG-ARDPAERSCAADQCDTFFRVCLKEYQSRVSSGGP---CSYGSGSTPVIGGNTFSVKP--LDQTNDKTR-----------IVLPFSFAWPRSYTLIVEALDFNNDSSTGSINGQVIEKAVQSGMINPNRQWQVLKHNGPVAQFQYQIRVTCDEHYFGFGCNKFCRPRDDFFGHYTCDHNGNKTCLEGWAGPECNTAICKQGCSIEHGSCKVPGNCRCLYGWQGEYCDQCIPHPGCVHGTCI-EPWQCLCDTNWGGQLCDKDLNTCGTLQPCLNGGTCSNTGPDKYHCACPDGYSGQNCERADNACLSEPCLNGGLCVESSLG--------------------------------------------------------------FECQCAAGWTGPSCNINEDDCSPNPCNHSGVCVDLVDGFKCICPVQWTGKTCLIDANECEE--------------------------------------------SPCVNAHSCRNLIGGYFCECLPGWTGQNCDINVNDCHGQCLNGGLCKDLVNGYRCVCAAGFAGDRCERDVDECASRPCLNGGRCQDTLNGFQCLCPPGFSGATCQLDLDY-CESGPCQNGAQCFSLASDYYCKCPEDYEGKNCSQLKDHCLITPCQVIDSCTVAVVSNSTPGGLRLISSSVCGPHGRCRSHSHAGGHFSCDCQDGFTGTYCHENINDCESSPCLSGGTCIDKINAYQCICADGWEGPNCETNIDDCRTNPCRDRGVCRDLVNDFYCECENGWKGKTCHSRESQCDEDTCNNGGTCSDEGDSFKCLCSPGWEGATCNIAKNSSCLPNPCENGATCVVTGDGFTCVCKEGWEGPTCSQNSNDCNPQPCYNSGTCVDGDNWYRCECASGFAGPDCRININECQSSPCAFGSTCVDEINGYRCLCPPGRTGPRCQEVT--GRPCVIGG------------------RIAVDGAKWAEDCNTCYCHKGIVTCTKLFCGPKACRMLGSG------RGDCPTGQLCVPVRDEQCFVKPCSSQGECWSAHRPAVRTH---------CQPDSH----CANVTFTFNKDTMPQGVTVEQVCRELRHLYVTKNVTSEF--------SISVSCELSSAASNEIHVAIHVTENG-IHGRVPVKEI-----------TDNIIDLVSKHSANSSVIGSIAEVRVQRKQPQNPNVDYMVPLLVSVVTAIWVLALASVFLWCIRHHRKQSSSATAINPTSPFSTPEENTANNARE-HLNQIKNHIEKNASNG--SLPGKELHCDDKNTVNAKIRT---------QFPES---DASRRLQKTRFPHQPAYMLVDRDDRLSSNGTDIKKHPQWTNKRDNRDLESQHRVPDSQHRDSQHSLQKMEYIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18168-1", "uniprot_id": "SERR_DROME", "id": "P18168-1", "name": "Protein serrate", "aln": "MYKMFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLPSTIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNATTKILGGSSFVLS-------DPGVG----------AIVLPFTFRWTKSFTLILQALDMYNTSYPD--AERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKEN-CTPSPCLEG-HCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSAT------------------------------TTTTTTTTATTTRKMAKPSGLPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPG-------------------APDKALQP----------------HCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCENGTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVGKGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVELTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRTSSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLRAATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGS--DVLATTVMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **. . * * .::****** . *::* .:: ::*...* :::** * *.:::**:::* * * : :* . * : * . : : * : :** * *:. *.. ****:: ****:*. *:: *::** * :*: *:*: **. ** * ** * * **:* *::*: :*** ** * ..* * *:.**** ***:*** **: ** : *** *: **:* * * :* * :*. .:.* : ** * * * . : * *. ** *.:* : *:* . * .*.* * .**.* * .* * .* :*.*** **:** *:* ..: * * ** * .* *::.* *** :.. * * :.* * * *: * ** : .**: ** ** * . :.* * * :* *: : * ..** : :* . .::* *. : ** *. : * .*. . . : .:: . . ** . *:* * * * * *: : ::* :** * * * .** * * ..*..* * .* * * ***** * :.: . * * ** * *:. ::* **:*.* * .* .*:** ** **:*******::**...** *:**:* *.** * ** *: * *. . :.. . :.** * * .* *: : ** * * : * *: ** * * . **.:*: : : : * :. :* : : : : *: . . :.::: : : ::: : . :: :* . . .: . * : ::: * * . : . : . :. . . ", "identical_positions": 278, "similar_positions": 234, "identity": "18.6%" }, { "cls_id": "homologset.agr.FB:FBgn0004198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53565-1", "uniprot_id": "CUX1_RAT", "id": "P53565-1", "name": "Homeobox protein cut-like 1", "aln": "----------------------------------------------------------------------------------MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKN------------TPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDLGQQLEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIK-----ALKEKIREYEQTLKSQAETIALEKEQ--KLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAET------------------------------LREQLSSANHSLQLASQIQKAPDV--AIEVLTRSS-LEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEDVKKELTTLKSMEFAPSEGAGTQD---------------------STKPLEVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPP---------------------------------------------------------------------------QLPRNTG-EQVSNTNGTHHFSPAGLSQDFFSSNLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQSPDVNGMAPSPSQSE---------------------------------------------------------------------------------------------------SAGSISEGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQR----------------------GNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQA-------SSTASSGNSDD----------------------------AIRSILQQARREMEAQQAALDPALKPAPLSQPDLTILNPKLLSASPMSTVSTYPPLAISLKKTPAAPEASTSALPSAPALKKEAQDAPTLDPPGSADATPGVLR-----------------------PVKNELVRGSTWKDPWWNPVQPERRNLTTSEETKADETNASGKEK-----TGSSQPRAERSQLQGPSATAEYWKEWPNAESPYSQSSELSLTGASR---SETPQNSPLPSSPIVPMAKPAKPSVPPLTPE-------------QYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNG--------------------------------------------------------------------------------ELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPTIETSKEGKPPEPSDPPTSDSQPTTP---------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRR------HSSVSDSQPCEPPSVGIDY-SQGASPQPQH---QLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDS------PSARSSRAAPSSEGDSCDG---------------VEAADTEEPGGNIVAT------------KSQGGPAEVTAAPADREEATQPAEKAKAQPLSSGTPGQ----DDGEDAGRSRPPPEGLADAPAPVPNLAAPAAGEDAATSATAPAMATEA---PGAARAGPAERSSALPSTSAPANAPARRPSSLQSLFGLPEAAG--ARD---NPVRKKKAANLNSIIHRLEKAASREEPIEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53564-1", "uniprot_id": "CUX1_MOUSE", "id": "P53564-1", "name": "Homeobox protein cut-like 1", "aln": "----------------------------------------------------------------------------------MLCVAG-----------AKLKRELDATATVLANRQDESEQSRKRLIEQSREFKKN------------TPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDVGQQLEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIK-----ALKEKIREYEQTLKSQAETIALEKEQ--KLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAET------------------------------LREQLSSANHSLQLASQIQKAPDV--AIEVLTRSS-LEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEEVKKELNTLKSMEFAPSEGAGTQD---------------------STKPLEVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPP---------------------------------------------------------------------------QLPRNTG-EQVSNTNGTHHFSPAGLSQDFFSSNLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQSPDVNGMAPSPSQSE---------------------------------------------------------------------------------------------------SAGSISEGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNRLFQEVPKRRNRSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQT-------SSTSSSGNSDD----------------------------AIRSILQQARREMEAQQAALDPALKPAPLSQPDLTILTPKHLSASPMSTVSTYPPLAISLKKTPAAPETSTAALPSAPALKKEAQDVPTLDPPGSADAAQGVLR-----------------------PMKSELVRGSTWKDPWWSPIQPERRNLTSSEETKADETTASGKER-----AGSSQPRAERSQLQGPSASAEYWKEWPSAESPYSQSSELSLTGASR---SETPQNSPLPSSPIVPMAKPAKPSVPPLTPE-------------QYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNG--------------------------------------------------------------------------------ELGQGVLPVQGQQQGPVLHSVASLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPAIETSKEGKPPEPSDPPASDSQPTTP---------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRR------HSSVSDSQPCEPPSVGIDY-SQGASPQPQH---QLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDS------PSARSSRAAPSSEGDSCDG---------------VEATDAEEPGGNIVAT------------KSQGGLAEVAAAPADREEATQPAEKAKAQPLCSGTPGQ----DDGEDASRPRPLPEGLADAPAPVPSLAAPAAGEDAATSATAPATATEA---PGAARAGPAERSSALPSTSAPANAPARRPSSLQSLFGLPEAAG--ARD---NPVRKKKAANLNSIIHRLEKAASREEPIEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39880-1", "uniprot_id": "CUX1_HUMAN", "id": "P39880-1", "name": "Homeobox protein cut-like 1", "aln": "----------------------------------------------------------------------------------MLCVAG-----------ARLKRELDATATVLANRQDESEQSRKRLIEQSREFKKN------------TPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIK-----ALKEKIREYEQTLKNQAETIALEKEQ--KLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAET------------------------------LREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSS-LEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQD---------------------AAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPS---------------------------------------------------------------------------QLPRNPG-EQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPDVNGMAPSPSQSE---------------------------------------------------------------------------------------------------SAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQP-------SSASGSGNSDD----------------------------AIRSILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLR-----------------------QVKNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGG-GKEKGSGGSGGGSQPRAERSQLQGPSS-SEYWKEWPSAESPYSQSSELSLTGASR---SETPQNSPLPSSPIVPMSKPTKPSVPPLTPE-------------QYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNG--------------------------------------------------------------------------------ELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTP---------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRR------HSSVSDSQPCEPPSVGTEY-SQGASPQPQH---QLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDS------PSARSGRAAPSSEGDSCDG---------------VEATEGPGS-ADTEEP------------KSQG--------EAEREEVPRPAEQTEPPP--SGTPGP----DDARDDDHEG----GPVEGPGPLP---SPASATATAAPAAPEDAATSA---AAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQSLFGLPEAAG--ARDSRDNPLRKKKAANLNSIIHRLEKAASREEPIEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70298-1", "uniprot_id": "CUX2_MOUSE", "id": "P70298-1", "name": "Homeobox protein cut-like 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MVAPVLKSFQAEVVALSKRSREAEAAFLSVYKQLIEAPDPVPSFEVARTLDDRLQRPSFDPS-GQRLQDVHIAWKRCPEPPSAREQNEG----TCPTGHTPANGNHLPG-PEDTLVTDT---LLQKNEAERQKGLQEVHITLAARLGEAEEKIKVLHSALKATQTELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES------------------------------LREQLASVNSSIRLACCSPQGPSGEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLASSTCSLPQ---------------------TLAKPDDPLLVAKDVFFPTQKFLLEKP-ALLASPEEDPSEDDSIKGSLGTEPPYPP----------------------------------------------------------------------------QLPPPPGPEDPLSPSPAQPLLGPSLGPDGPRTFSLSPFPSLAPGERLAGDSLLSKHMMGPA---AFKGETGNLLAFPPTFYGGAKPPSAPAASVPCPEPTGAPEAVDG-----------------------------------------------------------------------------------------------------AGP--EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGESKNSPASVSIPNGTASSSTSED----------------------------AIKNILEQARREMQAQQQALLEMES------------GPRGRSVPPSPPERPSPATASQNGALTCVKQEDGGGG----SGSSSTVQAP-LAVLSPAAFVQRIIR-----------------------KVKSEIGDAG-YFDHHWASDR---GLLSRPYASVSPSLSSSSS--YSGQPNGRAWPRGDEATIA---PEDEAA--MGEDE--APRVGELKAEAGA-----PEVGGGRLPYYPAY-VPRTLKPTVPPLTPE-------------QYELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSD--------------------------------------------------------------------------------QLGQGQGQAPTQQPS------------------ASQASPTEPTSSPSPPPSPTE-PEK-TSQEPLGLS----LESSKENQQPEGRASSSLGGKPFS-------------------SSQAAGGIQEMVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLSDPHNVEKLRDMKKLEKKAYLKRR------YGLIGTGSDSESPAAHSECPSPCLQPQELS-LMQAKKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDDPDFDPSGGPNVLTPGHTHREPTPQSPDSETEDQKPPMKSLELQE--PEGPLQRAAPDRALVKIKQE---EGLEVDGDSQPQDVGDPDRGQDGPKEEHTHPLGNSDLSELAPGPFLSGTPNPDCPSLHNPQEKGTGEQVHSEPLSFKSTSESSCCSLEGPPNSPSVISS---PDLTTCVSPAPSSSAPISPSLPGAPPAKVPSTSPTGDTAAALHPSTKVNPNLQRRHEKMANLNSIIYRLERAANREEVLEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LCK9-1", "uniprot_id": "A0ABK0LCK9_RAT", "id": "A0ABK0LCK9-1", "name": "Homeobox protein cut-like", "aln": "------------------------------------------------------------------MAAEGGPRGARGPRPARAARATRGPRARRRLDLRRLQ-ELNSVASELSVPQEESEHSPKRLIELRREFKKN------------VPEGIRAMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPSVEVARTLDDRLQRPSFHPS-GQRLRDVHISWKRCPEPPSAREQNEG----TCPTGHTPANGNHLPG-PEDTLVTDT---LLQKDEAERQKGLQEVHVTLAARLGEAEEKIKVLHSALKATQTELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES------------------------------LREQLASVNSSIRLACCSPQGPGGEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLASSTCSLPQPCFPSP--------------QALGKPDDPLLMAKDAFFPTQKLLLEKP-ALLASPEEDPSEDDSIKGSLGMEPSYPP----------------------------------------------------------------------------QLPPPPGPEDPLSPSPTQPLLGPSLGPDGPRTFSLSPFPSLAPGERLAGDPLLSKHMMAPV---AFKGETGNLLAFPPAFYGGAKPPTAPAAPVPGPEPSGAPEPVDG-----------------------------------------------------------------------------------------------------AGP--EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGESKNSPASVSIPNGTASSSTSED----------------------------AIKNILEQARREMQAQQQALLEMES------------GPRGRSVPPSPPERPSPATMSQNGALACVKQEDGGCS----SSSSGSAQAP-LAVLSPAAFVQRIIR-----------------------KVKSEIGDAG-YFDHHWASDR---GLLSRPYASVSPSLSSSSS--YSGQPNGRAWPRGDEATIA---PEDEAATGMGEDE--APRVGELKAEAGV-----SEVGGGRLPYYPAY-VPRTLKPTVPPLTPE-------------QYELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSD--------------------------------------------------------------------------------QLGQGQ--APNQQPS------------------ASQASPTEPTSSPSPPPSPTE-PEK-TSQEPLGLS----LESSKENQQPEGRASSTLGGKPLS-------------------SSQTTGGIQEMVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMRLWLSDPHNVEKLRDVKKLEKKAYLKRR------YGLISTGSDSESPAAHSECPSPCLQPQELS-LMQAKKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVVNWFHNYRSRMRREMLVEGTQDDPDFDPSGGSSVLPSGHTHTDPTPQSPDSEIEDQKPPMKSLELQE--PESPVHQAAPDRAVVKIKQE---EGLEVDGDSQPQDIGDPDRGQGGPKEEDTHPLGNNELSELVPGPFLPGTPNPDCSSLHTPQAKETGEQVHSEPLSFKSTSESSCCSLEGPPNSPSAISS---PDLMTCVSPAPSSSAPISPSLPGTLPAKVPSTSPTADPAAALHPSTKVNPNLQRRHEKMANLNSIIYRLERAANREEALEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14529-1", "uniprot_id": "CUX2_HUMAN", "id": "O14529-1", "name": "Homeobox protein cut-like 2", "aln": "----------------------------------------------------------------------------------MAANVGSMFQYWKRFDLRRLQKELNSVASELSARQEESEHSHKHLIELRREFKKN------------VPEEIREMVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQPPSFDPS-GQPRRDLHTSWKRNPELLSPKEQREG----TSPAGPTLTEGSRLPGIPGKALLTET---LLQRNEAEKQKGLQEVQITLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQREVES------------------------------LREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEIKTELSILKAMKLASSTCSLPQG---------------------MAKPEDSLLIAKEAFFPTQKFLLEKP-SLLASPEEDPSEDDSIKDSLGTEQSYPSPQ--------------------------------------------------------------------------QLPPPPGPEDPLSPSPGQPLLGPSLGPDGTRTFSLSPFPSLASGERL---------MMPPA---AFKGEAGGLLVFPPAFYG-AKPPTAPATPAPGPEPLGGPEPADGGGGG------------------------------------------------------------------------------------------------AAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIESQKGGEPKTSVAPLSIANGTTPASTSED----------------------------AIKSILEQARREMQAQQQALLEMEV------------APRGRSVPPSPPERPSLATASQNGAPALVKQEEG---------SGGPAQAP-LPVLSPAAFVQSIIR-----------------------KVKSEIGDAG-YFDHHWASDR---GLLSRPYASVSPSLSSSSSSGYSGQPNGRAWPRGDEAPVP---PEDEAAA-GAEDE--PPRTGELKAEGAT-----AEAG-ARLPYYPAY-VPRTLKPTVPPLTPE-------------QYELYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLSD--------------------------------------------------------------------------------QLGQAVG----QQPG------------------ASQASPTEPRSSPSPPPSPTE-PEK-SSQEPLSLS----LESSKENQQPEGRSSSSLSGKMYS-------------------GSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRR------YGLISTGSDSESPATRSECPSPCLQPQDLS-LLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPDLDPSGGPGILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQMEEDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQQESEAGERLHPDPLSFKSASESSRCSLEVSLNSPSAASS---PGLMMSVSPVPSSSAPISPSPPGAPPAKVPSASPTADMAGALHPSAKVNPNLQRRHEKMANLNNIIYRVERAANREEALEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G8V1-1", "uniprot_id": "A0AC58G8V1_DANRE", "id": "A0AC58G8V1-1", "name": "Homeobox protein cut-like", "aln": "------------------------------------------------------------------------------MCCLLRLLSLSLSLSLSPSPMTVAERELNSVAAQLAGRQEESEDSHKHLVELSREFKKN------------VPEDVLEMVSPVLKSFQAQVVALSQRSKEAESAFLAIYKQLIEAPDPAPLLEATQQRLAELQR-SAPEG-DALITEVSDRWRRRLECLDKAEHTEEEGPVTVETGEVSTQKPHMMTPNSTQTVQDGDAPLQNHQEPLQGEEEDQSDAPLPVRLDQAELRIKALQSSLSTARTELQELRCKYDQEKAEKLEEMCALMANLEKANQRADAAQREVEK------------------------------LREQLSGTQSTSKGTGPSEERPKEERE-----RDERLEALLFSKDREILRLLENVQRLQFTLQEVQDSSANQIAELERQLAYKSEAIETLETKLQSQIDYEEIKTELSILKAMKLASANGSSSQE---------------------SGKTAEALLLDKEAFLPSHKFLVDKV-KVLHNSDDGHSEKS--NDVSRPAGSYSS------------------------------------------------------------------------------PPGTLPIDGRTSSSPAPPTSDTSTHTLPRPFSVSPFSGEKLQDQLLQK------QLLSP---LFKKDGSSIMAFPTALYAAKAALLSANHSASIPITMETGMPSDQSESG------------------------------------------------------------------------------------------------SSGGG-DDDQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNILALRTIQVRQR----------------------GSITPRIRTPETGSDDAIKSILEQAKKEIQSQRG-DCKSSLGCPSGRSSTGAGSSSDE----------------------------AIKSILEQARREMQAQQQALLEMEV------------CGRSSASERLSIHDPPKSQASS--TPPFIKQEEGISVPQSLSNPTGSPQTP-LSVLSPAAFVQNIIR-----------------------KVKSEIGEAGTYFDQHWSVERS--AAVMGPFTSVSPSLSSSSS---TSMP--RPWPRIENGDCP---ANGEDTS-APEDEPMLSRQVEIKVEPDASVSSEASCGGGRVSFYPTY-IPRTLKPTVPPLTPE-------------QYEMYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLLD--------------------------------------------------------------------------------QLGHGLN-QLPNHNH------------------SQEKSPVTSRSSPSPPASPAD-AQSSTVLEPVSLA----LESSKENQQPQPPQPLEPHGVKSSVM--------------IPQQTHTPLGIQELVAMSPELDTYAITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVDKLRDVKKMEKKAYLKRR------YGLLSPGSDSDSPGAHSDCISPGLSALDLCPFSQAKKPRVVLAAEEKEALRKAYLQEPYPSQHTIEMLAAQLNLKTNTVINWFHNYRSRMRREVLMEGLQDN-DTDAEHN--------NYSPLASHSPVSDREDRKQ----------------PPSVRNRSVSTIPHR----------FAIKQETTEPEDEELRLRQDKCFSIG--AFKSEEPGRSLNLLPDGPQRNSSASHEGEELEKSPEDPVSFKASSEPSRSSLEVSLNSPSAASS---PGLMMSVSPVPSSSAPISPSPPNPPALEPPSLN------------AKLNKNTQRRNEKMANLNNIIHRLERAANREETLEWEF-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TRJ5-1", "uniprot_id": "A0AB32TRJ5_DANRE", "id": "A0AB32TRJ5-1", "name": "DNA-binding protein SATB", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQIIMKRLLDFSS---------------------------------------------------------------------------DGLEKIFIRRDQEVQRLEQEVQRLQRRLQEVQEKTANHIALLQQQLANKTQDVERLQVKLQSQQDYEKIKTELRSLRALTQTDLHVVSVTP------------------------APPSVSVENDDVIEVQ--------------------------------------------------------------------------------------------------------------------------VKTPDFHHSFGQEEELHESFSIISGRPVQNCRS--------------------------------------SSSSSSSPGSLQMVIKADPDSDVFLDS----------------------------------------------------------------------------------------------------------DEQELDTLQVTQQVKQALQSRNIGQRAFGHYVLGLSQGSVSDILARPKPWSKLTRRGKEPFLRMKHFLSDEHSMRTLSGIQETLR-----------------------GLAPCVRPTDVSSDQAIRNILDQSRLEMLDEELRSVHSS----------SSSDVSEN----------------------------AIRIILQGAQQQMQTNQSPITLEEQ-------------MRCGTLDP--------------------------------------------SIQTPADFVQGIIQ-----------------------KVKYEI--------------------------------------------------------------------------------------------------------------DEDVQPPVS--------------------------------------------------------------LSSVNQPHHGWSVENRDAEERFR----------------------------------------------------------------------------------------------------------------------------SSPTVCG----------------------------------------------------------------------------------LDLQNLELDTFSITQRVKKTLIVHNIGQRVFGEEVLGLTQSSVSELLSHPKPWTKLSLKGKENFIRMHLWLRDPHSVQKLNAKKKSDQRARLKRD------SQSVCEALECG----------------DVWRVDALKRPRVVLSVQEKQTLFSAYELEPYPSQNTIDRLAAQLGLQTSTVSNWFYNYRSRIRRDGFCEPAQVRRSSPAGLSLLS----LASAAVKQAPRDPEADDTDG----------------HVSVGVQSFMRLKEE---------------------------REED---------------------------------------------------PDSFCSSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10180-1", "uniprot_id": "CUT_DROME", "id": "P10180-1", "name": "Homeobox protein cut", "aln": "MQPTLPQAAGTADMDLTAVQSINDWFFKKEQIYLLAQFWQQRATLAEKEVNTLKEQLSTGNPDSNLNSENSDTAAAAATAAAVAAVVAGATATNDIEDEQQQQLQQTASGGILESDSDKLLNSSIVAAAITLQQQNGSNLLANTNTPSPSPPLLSAEQQQQLQSSLQQSGGVGGACLNPKLFFNHAQQMMMMEAAAAAAAAALQQQQQQQSPLHSPANEVAIPTEQPAATVATGAAAAAAAAATPIATGNVKSGSTTSNANHTNSNNSHQDEEELDDEEEDEEEDEDEDDEEENASMQSNADDMELDAQQETRTEPSATTQQQHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQHVASSAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPAVLLAAKDKEIKALLDELQRLR----AQEQTHLVQIQRLEEHLEVKRQHIIRLEARLDKQQINEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSNADLPESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAAAAAAAAAAACANDPNKFQALLIERTKALAAEALKNGASDALSEDAHHQQQQHHQQQHQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLPGLPAFQFAAAQVAAGGDGRGHYRFADSELQLPPGASMAGRLGESLIPKGDPMEAKLQEMLRYNMDKYANQALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKSLIPKKDSG---------------LPQYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRSHGGEDSHSNEDSKSPPQSCTSPFFKVENQLKQHQHLNPEQAAAQQREREREQREREQQQRLRHDDQDKMARLYQELIARTPRETAFPSFLFSPSLFGGAAGMPGAASNAFPAMADENMRHVFEREIAKLQQHQQQQQAAQAQAQFPNFSSLMALQQQVLNGAQDLSLAAAAAKDIKLNGQRSSLEHSAGSSSCSKDGERDDAYPSSLHGRKSEGGGTPAPPAPPSGPGTGAGAPPTAAPPTGGASSNSAAPSPLSNSILPPALSSQGEEFAATASPLQRMASITNSLITQPPVTPHHSTPQRPTKAVLPPITQQQFDMFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQQHLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPPSAGGAQPGGPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVRSSRRKPAAPQWVNPAGAVTNPSAVVAAVAAAAAAAADNERIINGVCVMQASEYGRDDTDSNKPTDGGNDSDHEHAQLEIDQRFMEPEVHIKQEEDDDEEQSGSVNLDNEDNATSEQKLKVINEEKLRMVRVRRLSSTGGGSSEEMPAPLAPPPPPPAASSSIVSGESTTSSSSSSNTSSSTPAVTTAAATAAAGWNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34237-1", "uniprot_id": "CASP_YEAST", "id": "P34237-1", "name": "Protein CASP", "aln": "---------------------------------------------------------------------------------MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKETLSLNSRKSLATETKKFKKLE------------PEEKLNNVNKIIKQYQREIDNLTQRSKFSEKVLFDVYEKLSEAPDPQPLLQSSLEKLG------------------------------------------------------------------------------------------------------------KIDDSKELKEKISYLEDKLAKYADYETLKSRLLDLEQ----------------------------------------------------------------------------------SSAKTLAKRLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNEDGDQENNQKEVSTRIAEYN------------------------------LVTQELETTQARIYQLE------------------------------------------------------------------------------------------------------------------------KRNEELSGALAKATSEAEKETELHAK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELKLNQLESENALLSASYEQ---ERKSTSHAINELKEQLNSVVAESESYKSELETVRRKLNNYSDYNKIKEELSALKKIEFGVN----------------------EDDSDNDIRSEDKNDNTFESSLLSANKKLQATLAEYRSKS---------TAQEEERNE-----------------------------LKKSVDQLKQQIATLKEANEKLET-----------DLEKVENVSP--------------------------------------------HFNETASMMSGVTR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QMNNRTSHKMSPTSSIIGIPEDGELSGNQSTILPIVTKQRDRFRSRNMDLEKQLR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QGNSEKGKLKLEISKLKGDNTKLYERIRYLQSYNNNNAPVN----------QSTERIDVESQYSRVYDESLHPMANFRQNELNHYKNKKLSALEKLFS------------------------------------------------SFAKVILQNKMTRMVFLFYCIGLHGLVFMMSMYVINISGYMTPEVGIVQSAKSSSNLNGGLGGAEKVAAGVGSVHGINR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . *.:. : * .:* . *: ::. : * : . :: . : . : :* : :. : :..:::..:.: . : . : .. : * : : : .:: : * .: : .. : : ::: : : * : : : . * : . . *. : ::: :* . : . :: : . : : :. . : .:: : . .:* :. . :*:: .. : : : :. ::. . . . . : . : ", "identical_positions": 15, "similar_positions": 121, "identity": "0.68%" }, { "cls_id": "homologset.agr.FB:FBgn0004227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLH4-1", "uniprot_id": "PSPC1_RAT", "id": "Q4KLH4-1", "name": "Paraspeckle component 1", "aln": "---------------------------------------------MMLRGNL-----------KQVRIEKNP------------ARLRALESAAGES-----------------------------------------------------EPVAAAAMALTLAGEQPPP-PAPS-----------------------------------------------------------------------------------------------EEHPDEEMG--FTIDIKSFLK----PGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYG-EPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQ-QYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIR--HREQEELRRQ-QEG-FKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGTQGPPPMMGMNMNNRGTIPGPPMGPGPAMGPEGAANMGTPMIPDNGAVHNDRFPQGPPSQMGSPMGNRTGSETPQAPMSAVGPVS---GGPGGFGRGSQGGNFEGPNKRRRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R326-1", "uniprot_id": "PSPC1_MOUSE", "id": "Q8R326-1", "name": "Paraspeckle component 1", "aln": "---------------------------------------------MMLRGNL-----------KQVRIEKNP------------ARLRALESAAGES-----------------------------------------------------EPVAAAAMALTLAGEQAPP-PAPS-----------------------------------------------------------------------------------------------EEHPDEELG--FTIDIKSFLK----PGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYG-EPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQ-QYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIR--HREQEELRRQ-QEGGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGTQGPPPMMGMNMNNRGTIPGPPMGPGPAMGPEGAANMGTPMIPDNGAVHNDRFPQGPPSQMGSPMGNRTGSETPQAPMSGVGPVS---GGPGGFGRGSQGGNFEGPNKRRRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXF1-1", "uniprot_id": "PSPC1_HUMAN", "id": "Q8WXF1-1", "name": "Paraspeckle component 1", "aln": "---------------------------------------------MMLRGNL-----------KQVRIEKNP------------ARLRALESAVGES-----------------------------------------------------EPAAAAAMALALAGEPAPPAPAPP-----------------------------------------------------------------------------------------------EDHPDEEMG--FTIDIKSFLK----PGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYG-EPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQ-QYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIR--HREQEELRRQ-QEG-FKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMSGVGPVS---GGPGGFGRGSQGGNFEGPNKRRRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5FVM4-1", "uniprot_id": "NONO_RAT", "id": "Q5FVM4-1", "name": "Non-POU domain-containing octamer-binding protein", "aln": "----------------------------------------------MQSN-------------KTFNLEKQN------------HTPRKHHQHHHQQ-----------------------------------------------------HHQQQQQQQQQQQQQPPPPIPANG-----------------------------------------------------------------------------------------------QQASSQNEG--LTIDLKNFRK----PGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYG-KAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQ-QFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR--QQE-EMMRRQ-QEG-FKGTFPDAREQEIRMGQMAMGGAMG----------------------INNRGAMPPAPVPPGTPAPPGPAA-----MMPD-GTLG-----------LTPPTTERFG---QAATMEGIGAIG---GTPPAFNRPAPGAEFA-PNKRRRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K48-1", "uniprot_id": "NONO_MOUSE", "id": "Q99K48-1", "name": "Non-POU domain-containing octamer-binding protein", "aln": "----------------------------------------------MQSN-------------KAFNLEKQN------------HTPRKHHQHHHQQ-----------------------------------------------------HHQQQQQQQQQ---QPPPPIPANG-----------------------------------------------------------------------------------------------QQASSQNEG--LTIDLKNFRK----PGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYG-KAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQ-QFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR--QQE-EMMRRQ-QEG-FKGTFPDAREQEIRMGQMAMGGAMG----------------------INNRGAMPPAPVPPGTPAPPGPAT-----MMPD-GTLG-----------LTPPTTERFG---QAATMEGIGAIG---GTPPAFNRPAPGAEFA-PNKRRRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15233-1", "uniprot_id": "NONO_HUMAN", "id": "Q15233-1", "name": "Non-POU domain-containing octamer-binding protein", "aln": "----------------------------------------------MQSN-------------KTFNLEKQN------------HTPRKHHQHHHQQ-----------------------------------------------------QHHQQQQQQPP-----PPPIPANG-----------------------------------------------------------------------------------------------QQASSQNEG--LTIDLKNFRK----PGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYG-KAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQ-QFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRR--QQE-EMMRRQ-QEG-FKGTFPDAREQEIRMGQMAMGGAMG----------------------INNRGAMPPAPVPAGTPAPPGPAT-----MMPD-GTLG-----------LTPPTTERFG---QAATMEGIGAIG---GTPPAFNRAAPGAEFA-PNKRRRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GFD8-1", "uniprot_id": "A0A8I6GFD8_RAT", "id": "A0A8I6GFD8-1", "name": "", "aln": "MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPG--GPKPPLPPPPPHQQQQQPPPQQPPPQQPPPHQQPPPHQPPHQQ--PPPPPQES-KPVVPQGPGSAPGVSTAPPPAVSAPPANPPTTGAPPG--PGPTPTPPPAVPSTAPGPPPPSTPSSGVSTTPPQTGGPPPPPAG--GAGPGPKQGPGPGGPKGGKMPGGPKPGGGPGMGAPGGHPKPPHRGGGEPRGGRQHHAPYHQQHHQGPPPGGPGPRTEEKISDSEVSRFWRKLSVSLRWRLLPTLGVFSPRPRQWR--PPFCPLPEALLRMLAKAGRTHGGLCIPCLKCFWYFQ-ESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNP-MYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHSQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGTMNMGDP----------------------YGSGGQKFPPLGGGGGIGYEANPG-----VPPATMSGS---------MMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGRE--EYEGPNKKPRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIJ6-1", "uniprot_id": "SFPQ_MOUSE", "id": "Q8VIJ6-1", "name": "Splicing factor, proline- and glutamine-rich", "aln": "MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPG--GPKPPLPPPPPHQQQQQPPPQQPPPQQPPPHQQPPPHQPPHQQ--PPPPPQES-KPVVPQGPGSAPGVSSAPPPAVSAPPANPPTTGAPPG--PGPTPTPPPAVPSTAPGPPPPSTPSSGVSTTPPQTGGPPPPPAG--GAGPGPKPGPGPGGPKGGKMPGGPKPGGGPGMGAPGGHPKPPHRGGGEPRGGRQHHAPYHQQHHQGPPPGGPGPRTEEKISDSEG--FKANLSLLRR----PGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYG-EPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNP-MYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHSQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGTMNMGDP----------------------YGSGGQKFPPLGGGGGIGYEANPG-----VPPATMSGS---------MMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGRE--EYEGPNKKPRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23246-1", "uniprot_id": "SFPQ_HUMAN", "id": "P23246-1", "name": "Splicing factor, proline- and glutamine-rich", "aln": "MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ-PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEG--FKANLSLLRR----PGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYG-EPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNP-MYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDP----------------------YGSGGQKFPPLGGGGGIGYEANPG-----VPPATMSGS---------MMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGRE--EYEGPNKKPRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PEX4-1", "uniprot_id": "A0A8M1PEX4_DANRE", "id": "A0A8M1PEX4-1", "name": "", "aln": "MSRDRSRNRGG----FQPRGRGG--MGMRGGMGMGMGMGMGMGMG-MGMGMG----NPNFRNQNQHHFQNRGPQMGGGFRQ---NQGNQGNQVSTQQ--KPQEPAQN-KPVVQTPPAQGPGQ--------AQQAANK-----------GPTPQQTPTVAPPKIQSAPPKIQSP-----PPKIQSPPPAQNN--------AKTPEIASPQNQQRKNLPKPAMGNGQKPPAPLKQEQTPAPTPPPAQQQQQQ--QQQQKQTP--------ANEQSSQPQE--LKATLSLLRK----PGEKTYTQRCRLFIGNLPNDITEPEFRKLFAKYG-EPSEIFINQGKGFGFIRLESRALAEVAKAELDDTPMKGRPLRVRFATHSAALSVRNLSPFVSNELLEEAFSQFGLVERAIVIVDDRGRSTGKGIVEFSSKPAARKAMDRISDGVFLLTSSPRPIVVELLEQYDDEDGLPEKLAQKNP-SYQKEREQPPRFARPGTFEYEYSQRWKSLDEMEKQQRQQVEKNICEAREKLETEMDDAYHEHQANMLRQDLLRRQEELRRMEELHSQEMQKRKEMQLRQEEERRRREEEMMR-QREIEEQLRRKREESYRMNNFMDNRDREMRMNTSGGMGLSDMS---------------------FGSPNQKFSLTG----MSFDGHQG-----LSGSTQGG----------LASNEMRNDRFQQGGSG-----GQRGIGAGN-SGFGRVRE--EFDGPAKKPRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04047-1", "uniprot_id": "NONA_DROME", "id": "Q04047-1", "name": "Protein no-on-transient A", "aln": "MESAGKQDNNATQQLPQRQQRGNQQANKNLGKHNAQKQNDSADGGPAEKKQR--FGGPNAQNQNQNQNQNGGVTGGGGAVGGPNQNKNFGNNKGGFVGNRNRNNNRAGNQNRTFPGNNNPNQKPNNETSKADGPNALAKNNEPATAAAGQNQANQNANKGQNQRQGQNQNQNQVHGQGNQGGPGNQGGAGNQGGQGNQGGAGNQGNGQGFRGRNAGNNQGGGFSGGPQNQQRDNRNRSGPRPGGGAGGAMNSTNMGGGGGGGGGGGPRGGEDFFITQRLRSISGPTFELEPVEVPTETKFSGRNRLYVGNLTNDITDDELREMFKPYG-EISEIFSNLDKNFTFLKVDYHPNAEKAKRALDGSMRKGRQLRVRFAPNATILRVSNLTPFVSNELLYKSFEIFGPIERASITVDDRGKHMGEGIVEFAKKSSASACLRMCNEKCFFLTASLRPCLVDPMEVNDDTDGLPEKAFNKKMPDFNQERSIGPRFADPNSFEHEYGSRWKQLHNLFKTKQDALKRELKMEEDKLEAQMEYARYEQETELLRQELRKREVDNERKKLEWEMREKQAEEMRKREEETMRRHQTEMQSHMNRQEEDMLRRQQETLFMKAQQLNSLLDQQEGFGGGG----------------------------GGNNSTFDNFAGNSNSPFEVFRG------NNNNN--------------STMIGNNAAPNTQDSFAFEFGVNN---MNQGGNQRGNNGGGNNVPWGRRRF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . : . . * :: * * : . : .:: * . : : * ::: : :. ** ** **. :.: **:*** :.: * * **. ****** ::*. ** :*:* : *****: *:*:***: *..* .: .: *:**: ** *: :: ** :***** *. :::**. **** .:**.**. *** * :: * ::: :.::: .:*** :*: * :*:: ::**:* :*: : .* : . . :: :::. *.** **:: ** .. * : *: :* : : . . . . * . . * * : *:", "identical_positions": 97, "similar_positions": 115, "identity": "12.86%" }, { "cls_id": "homologset.agr.FB:FBgn0004237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6URK4-1", "uniprot_id": "ROA3_RAT", "id": "Q6URK4-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "---MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAG-SQR-GRGG--G----------------SGNFMG-RGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGG-----YNGFGGD--GGNYGGGPG-YSS-RGGYGGGGPGYGNQGGGYGGGGGGYDGYNE------------------------------------GGNFGGGN----YGGGGNYNDFGNYSGQQQSNYGPMKGGSFGG---------RSSGSP---YGGG---------YGSGGGSGG--YGSR-RF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG05-1", "uniprot_id": "ROA3_MOUSE", "id": "Q8BG05-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "---MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAG-SQR-GRGG--G----------------SGNFMG-RGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGG-----YNGFGGD--GGNYGGGPG-YSS-RGGYGGGGPGYGNQGGGYGGGGGGYDGYNE------------------------------------GGNFGGGN----YGGGGNYNDFGNYSGQQQSNYGPMKGGSFGG---------RSSGSP---YGGG---------YGSGGGSGG--YGSR-RF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51991-1", "uniprot_id": "ROA3_HUMAN", "id": "P51991-1", "name": "Heterogeneous nuclear ribonucleoprotein A3", "aln": "---MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAG-SQR-GRGG--G----------------SGNFMG-RGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGG-----YNGFGGD--GGNYGGGPG-YSS-RGGYGGGGPGYGNQGGGYGGGGG-YDGYNE------------------------------------GGNFGGGN----YGGGGNYNDFGNYSGQQQSNYGPMKGGSFGG---------RSSGSP---YGGG---------YGSGGGSGG--YGSR-RF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P4F7-1", "uniprot_id": "A0A8M1P4F7_DANRE", "id": "A0A8M1P4F7-1", "name": "", "aln": "-------------------------MESRDSKEPEQLRKLFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSEVDAAMTARPHKVDGRVVEPKRAVSREDSNKPGAHLTVKKIFVGGIKEDTEEYHIREYFECYGKIETIDIMEERSTGKKRGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQEMQSSS-NQR-YRGG--G----------------GGNFTG-RGGNFG--------------RGGYGGGR-------GGGDG------YNGFGG-----NYGGGPGGYGGGRGGYGGG-PGYGNQGG--GGGFGGFDNYNDRGN--------------------------------FGGNFGGGGGSSGGGGGGNYNDFGNYGGQQ-SNFGPMKGNNFGG---------RNSGPY---GGGG---------YGSGGGGGGGGYGSR-RY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A7VJC2-1", "uniprot_id": "ROA2_RAT", "id": "A7VJC2-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-----------------MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIFLQKYHTINGHNAEVRKALSRQEMQEVQ-SSRSGRGGNFG----------------FGDSRG-GGGNFGPGPGSNFRG----GSDGYGSGR-------GFGDG------YNGYGGGPGGGNFGGSPG-YGGGRGGYGGGGPGYGNQGGGYGGGYD---------------------------------------------NYGGGN-----YGSGNYNDFGNY-NQQPSNYGPMKSGNFGGS--------RNMGGP---YGGGN--------YGPGGSGGSGGYGGRSRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22626-1", "uniprot_id": "ROA2_HUMAN", "id": "P22626-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-----------------MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQ-SSRSGRGGNFG----------------FGDSRG-GGGNFGPGPGSNFRG----GSDGYGSGR-------GFGDG------YNGYGGGPGGGNFGGSPG-YGGGRGGYGGGGPGYGNQGGGYGGGYD---------------------------------------------NYGGGN-----YGSGNYNDFGNY-NQQPSNYGPMKSGNFGGS--------RNMGGP---YGGGN--------YGPGGSGGSGGYGGRSRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88569-1", "uniprot_id": "ROA2_MOUSE", "id": "O88569-1", "name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "aln": "-----------------MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQ-SSRSGRGGNFG----------------FGDSRG-GGGNFGPGPGSNFRG----GSDGYGSGR-------GFGDG------YNGYGGGPGGGNFGGSPG-YGGGRGGYGGGGPGYGNQGGGYGGGYD---------------------------------------------NYGGGN-----YGSGSYNDFGNY-NQQPSNYGPMKSGNFGGS--------RNMGGP---YGGGN--------YGPGGSGGSGGYGGRSRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49312-1", "uniprot_id": "ROA1_MOUSE", "id": "P49312-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS-SSQRGRSG-------------------SGNFGGGRGGGFG-------------GNDNFGRGGN-----------------FSGRGG------FGGSRG--GGGYGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNY-NNQSSNFGPMKGGNFGG---------RSSGPY---GGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09651-1", "uniprot_id": "ROA1_HUMAN", "id": "P09651-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS-SSQRGRSG-------------------SGNFGGGRGGGFG-------------GNDNFGRGGN-----------------FSGRGG------FGGSRG--GGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGG---------SYNDFGNY-NNQSSNFGPMKGGNFGG---------RSSGPY---GGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Y4L2-1", "uniprot_id": "RA1L3_HUMAN", "id": "A0A2R8Y4L2-1", "name": "Heterogeneous nuclear ribonucleoprotein A1-like 3", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPDAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS-SSQRGRSG-------------------SGNFGGGRGGGFG-------------GNDNFGRGGN-----------------FSGRGG------FGGSRG--GGGYGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNY-NNQSSNFGPMKGGNFEG---------RSSGPH---GGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04256-1", "uniprot_id": "ROA1_RAT", "id": "P04256-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASAS-SSQRGRSG-------------------SGNFGGGRGGGFG-------------GNDNFGRGGN-----------------FSGRGG------FGGSRG--GGGYGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNY-NNQSSNFGPMKGGNFGG---------RSSGPY---GGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32P51-1", "uniprot_id": "RA1L2_HUMAN", "id": "Q32P51-1", "name": "Heterogeneous nuclear ribonucleoprotein A1-like 2", "aln": "------------------------MSKSASPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVKGHNCEVRKALPKQEMASAS-SSQRGRRG-------------------SGNFGGGRGDGFG-------------GNDNFGRGGN-----------------FSGRGG------FGGSCG--GGGYGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNY-NNQSSNFGPMKGGNFGG---------RSSGPY---GGGGQYFAKPQNQGGYGVSSSSSSYGSGRRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GJN1-1", "uniprot_id": "A0A8I6GJN1_RAT", "id": "A0A8I6GJN1-1", "name": "Heterogeneous nuclear ribonucleoprotein A1", "aln": "------------------------LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS-SSQRGRNG-------------------SGNFGG-RGGGFG-------------GNDNFGRGGN-----------------FSGRGG------FGGSRG--GGGYGGSGDGYNGFGNDG----------------------------------------------------SNFGGGG---------SYNDFGNY-NNQSSNFGPMKGGNFGS---------RSSGSY---GGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PGI6-1", "uniprot_id": "A0A8M1PGI6_DANRE", "id": "A0A8M1PGI6-1", "name": "", "aln": "-----------------------MSKEGQ-PREPEQLRKLFIGGLSFETTDDSLRAHFEQWGTLTDCVVMKDPNTKRSRGFGFVTYSSVDEVNASMDARPHKVDGRLVEPKRAVSREDSSKPFAHTTVKKIFVGGIKDDTEENHLRDYFDQFGKIEVVEIMVDHKTGNKRGFAFVTFDDHDSVDRIVIQKYHTVNGHNCEVRKALSKQEMANTGRGGGGGGGGGGGNFNRYGNNGGYNNDFGGGGGGGNRDGYFGRGGRGNNFG-GGGGGGGYGGGGDCYNNNNGFGGGG--YGGGGGNGGGSPG-NYGGNRG---YG--GGGGGGHGYGNQGGGYGGGNSGGGGGGYNNYN--------------------NGNGNFGGGNFGGGGGGGGN----SGGGGNYNDFGNYNSQQS-NYGPMKG-NFGGGG-------RNSGPYGGGYGGGSSG-------SGGGGSGYGGGSGGRRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QHJ0-1", "uniprot_id": "A0A8M9QHJ0_DANRE", "id": "A0A8M9QHJ0-1", "name": "", "aln": "MPPAITPKKEREAESAVSHRVTAMSKEQQTPREPEQLRKLFIGGLSFETTDESLRAHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVGEVDAAMDARPHKVDGRAVEPKRAVSREDSSKPGAHSTVKKMFVGGIKEDTDEEHLREYFGQFGKIDEVNIMTEKNSDKRRGFAFITFDDHDAVDRIVIQKYHTVNGHNCEVRKALSREEMNRVSMNSRGGRGGGGG-------SGGGNFGRGGGGGGGGYGGGYGGGG-------GRGGGGGYGGG-DGYN---GYGGGNGISTDKSGYGGGGP--NYGGNRG---YGSGGGGGGGGGYGNQGGGYGGG------GGYDNYN--------------------NNGG--GGG--GGGNFGGGN----FGGGGDYNDFGNYNNQSSSNYGPMKGGNYGGGGGGGGR--SGGGPYGGGYGGGSGGGGGYGGGSGGGGGGYGGGSGGRRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48810-1", "uniprot_id": "RB87F_DROME", "id": "P48810-1", "name": "Heterogeneous nuclear ribonucleoprotein 87F", "aln": "--------------MAEQNDSNGNYDDGEEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDMDRQG--GGGGRGGPRAG------------GRGGQGDRGQGGGGWGGQNRQN-------GGGNWGGAGG------GGGFGNSGGNFGGGQGGGSGGWNQQGGSG--GGPWNNQGGGNGGWNGGGGGGYGGGN------------------------------------------SNGSWGGNG-----GGGGGGGGFGNE-YQQSYGGGPQRNSNFGNNRPAPYSQGGGGGGFNKGNQGGGQGFAGNNYNTGGGGQGGNMGGGNRRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **: ****.**.:.**::.*: ::*:**.:.* ***:** .**.*****:*:: :: : : **.:*** *******.*:: * * ****:***.:::* :* :*:** :*:* :::: :: :.::*** *: ***:*.**:*. ** *:::.:. :*:**: :::* * . * .. :* ..:* . .* ** *. * . *.* *:.. * . **.. . ..*** :. . ** :. .: . . * ** * . . .. *:", "identical_positions": 100, "similar_positions": 103, "identity": "21.01%" }, { "cls_id": "homologset.agr.FB:FBgn0004242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29101-1", "uniprot_id": "SYT2_RAT", "id": "P29101-1", "name": "Synaptotagmin-2", "aln": "---------------------------------------MRNIFKRNQEPIVAPATTTA---TMPLAPAAPADNSTESTGTG--ESQEDMFAKLKDKFFNEINKIP-----LPPWALIAMAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGG---------QDDDDAETGLTEGEGEGEEE--KEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEE-PEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46097-1", "uniprot_id": "SYT2_MOUSE", "id": "P46097-1", "name": "Synaptotagmin-2", "aln": "---------------------------------------MRNIFKRNQEPNVAPATTTA---TMPLAPVAPADNSTESTGPG--ESQEDMFAKLKEKFFNEINKIP-----LPPWALIAMAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGG---------QDDDDAETGLTEGEGEGEEE--KEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELAGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEE-PEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9I0-1", "uniprot_id": "SYT2_HUMAN", "id": "Q8N9I0-1", "name": "Synaptotagmin-2", "aln": "---------------------------------------MRNIFKRNQEPIVAPATTTA---TMPIG---PVDNSTESGGAG--ESQEDMFAKLKEKLFNEINKIP-----LPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGG---------QDDDDAETGLTEGEGEGEEE--KEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEE-PEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5C0-1", "uniprot_id": "F1R5C0_DANRE", "id": "F1R5C0-1", "name": "", "aln": "--------------------------------------MKWNVLKKKPAAMVGPEPTGASALTMAPAVSTPADNSTEHQGP---VSKNDVFGDIKNKFLNEMDKLP-----LPPWAIIAIAIVAVVLILTCCFCIVKKTCLKKKKGKK--GKKGKGDMGMKNMKGGEK-------QEEDDDEEDIDMGITEEKEEEPKEKEKLGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTLNPVFNETFHFK-IPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLDSAEKEE-PEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKAQGTELRHWSDMLANPRRPIAQWHPLKPEEEVDATLAALTAKK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21707-1", "uniprot_id": "SYT1_RAT", "id": "P21707-1", "name": "Synaptotagmin-1", "aln": "-----------------------------------------MVSASHPEALAAP---------VTTVATLVPHNATEPASPG--EGKEDAFSKLKQKFMNELHKIP-----LPPWALIAIAIVAVLLVVTCCFCVCKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKD-DDAETGLTDG--EEKEE-PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEE-QEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46096-1", "uniprot_id": "SYT1_MOUSE", "id": "P46096-1", "name": "Synaptotagmin-1", "aln": "-----------------------------------------MVSASRPEALAAP---------VTTVATLVPHNATEPASPG--EGKEDAFSKLKQKFMNELHKIP-----LPPWALIAIAIVAVLLVVTCCFCVCKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKD-DDAETGLTDG--EEKEE-PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEE-QEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21579-1", "uniprot_id": "SYT1_HUMAN", "id": "P21579-1", "name": "Synaptotagmin-1", "aln": "-----------------------------------------MVSESHHEALAAPP--------VTTVATVLPSNATEPASPG--EGKEDAFSKLKEKFMNELHKIP-----LPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKD-DDAETGLTDG--EEKEE-PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEE-QEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZ27-1", "uniprot_id": "Q5TZ27_DANRE", "id": "Q5TZ27-1", "name": "Synaptotagmin", "aln": "--------------------------------------------MSRREARVGNP--------APTAAPEVPGNSTEAAGPGPRETKDEMFSKVKNKFMNELHKIP-----LPSWAIVAIAFVAVVLVVSCCFCICKKWIFKKKNKKKGKDKG-KNAINMKDVKDG---IKTEALKDEDDAETGLTDT--EKEVE-PKEEEKLGKLQYSMDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQSAEKEE-QEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVGLNSTGTELRHWSDMLANPRRPIAQWHVLKPEEEVDALLAAQKK----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NEH4-1", "uniprot_id": "A0A8M1NEH4_DANRE", "id": "A0A8M1NEH4-1", "name": "", "aln": "---------------------------------------MRLASMQHRGRRAAES-------------EEEPNRAPPPLPPP--SHHSHNFVNMKNKFFNELGHLPNHKIRMPMWAIGAIIVVVLALVGCFAFCIYKKCLGGKKKTKKVRERKGGRRR-MK--KEG----------EEEAGEEQPKEG--EGEGE----KEYYGKLEYTLDYNFTENQLIVGILQAQDLPAMDIGGTSDPYVKVYMLPDKKKKFETKVQRKNLCPVFNETFIFK-IPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKIPMNSIDLGQPIHEYKDLVGGEKEE-QEKLGDICISLRYVPTSGKLTVCIMEAKNLKKMDVGGLSDPFVKIVLQHNGKRIKKKKTTVKQNTLNPYFNESFSFEIPFAQIQKVQVLITVYDYDKLGSNDPIGKCWIGFGASGVGLRHWSDMLANPRRPVAQWHTLQPEEEVDAALKAPIR----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PPX1-1", "uniprot_id": "A0A8M9PPX1_DANRE", "id": "A0A8M9PPX1-1", "name": "", "aln": "-------------------MESSLAKTESFLNKRPVHLHQSCRMHEDDAPLAASSSSPASLAQKESKIPGSTISSPTAVHPQT-TTADSLVHSIRSKFLNELHKVP-----LPSWATAALGFITVFIVLSCCLCIFRKMIFKKKKEKGGKEKNEKNDINMSNVKEE----------GTKQAVHHTTDSDAKEEDSESKEAQKLGKLLYTLDYNFTDSTLIVGVIRAEGLAAMDMSGTSDPYVKVYLLPDKKKKFETKVHRKTLEPTFNEHFTFK-VPYAELGGKTLVMTVYDFDRFSKHDAIGDVRLQMNKVDFSHLTEEWRDLQKAEKEE-QERLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPSEQIQLRNRAAPLVRHAGQSKK--------------------------THRPMARA----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21521-1", "uniprot_id": "SY65_DROME", "id": "P21521-1", "name": "Synaptotagmin 1", "aln": "MPPNAKSETDAKPEAEPAPASEPAADLESVDQKLEETHHSKFREVDRQEQEVLAEKAAEAASQRIAQVESTTRSATTEAQES--TTTAVPVIKKIEHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVRRFL-KKRRTKDGKGKKGVDMKSVQLLGSAYK-------EKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETDEILKNMK-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47861-1", "uniprot_id": "SYT5_RAT", "id": "P47861-1", "name": "Synaptotagmin-5", "aln": "-----------------------------------------------------------------MFPEPPTPGSPAPETPPD---------------SSRIRQGA-----VPAWVLATILLGSGLLVFSSCFCLYRKRC-RRRMGKKSQAQAQVHLQEVKELGRS-------YIDKVQPEIEELDPSPSMPGQQ-VLDKHQLGRLQYSLDYDFQTGQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEE-QEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGTAVGGAGLRHWADMLANPRRPIAQWHSLRPPDRARPIPAP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N5-1", "uniprot_id": "SYT5_MOUSE", "id": "Q9R0N5-1", "name": "Synaptotagmin-5", "aln": "-----------------------------------------------------------------MFPEPPTLGSPAPKTPPD---------------SSRIRQGA-----VPAWVLATIVLGSGLLVFSSCFCLYRKRC-RRRMGKKSQAQAQVHLQEVKELGRS-------YIDKVQPEIEELDRSPSMPGQQ-VSDKHQLGRLQYSLDYDFQTGQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEE-QEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAVGGAGLRHWADMLANPRRPIAQWHSLRPPDRARPIPAP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00445-1", "uniprot_id": "SYT5_HUMAN", "id": "O00445-1", "name": "Synaptotagmin-5", "aln": "-----------------------------------------------------------------MFPEPPTPGPPSPDTPPD---------------SSRISHGP-----VPPWALATIVLVSGLLIFSCCFCLYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQS-------YIDKVQPEVEELEPAPSGPGQQ-VADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREE-QEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9P4-1", "uniprot_id": "A0AB13A9P4_DANRE", "id": "A0AB13A9P4-1", "name": "", "aln": "-------------------------------------------MTPRPS----------------VKPTKTPHTNTTTAAPG--------------FLPSLLDRIP-----LPRWAIYAIFAAIVLLILICVICCCVKCCCKGKKKRKKKPDEKINMKGISGTTTT---------ALVQPETEDTEYS---------SSDQQRGKLQYSLEFNASRSELTVGIKEAAALKAMDSGGTSDPYVKVYILPNKSKTFETKVFRKTLNPVFNENFKYQ-IPQKELTESTLVMQVYDFNRFSKHDIIGEIRLNLSTVDWNHVIEEWRDLSEASKHE-QEHLGEICFSLRYVPTSSKLTVIILEAKNLKKMDQVGSSDPYVKVQLILEKKKWKKKKTSVKKRTLNPYFNESFTFDVSFEQIQKVQLVISVWDHDKMSRNDAIGKIYLGCDATGNQLRHWADMLSNPRKPVAQWHTLLSAEQVDTTLALKHTLKIPFTNKNF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8NBV8-4", "uniprot_id": "SYT8_HUMAN", "id": "Q8NBV8-4", "name": "Synaptotagmin-8", "aln": "-----------------------------------------------------------------MGHPPVSPSAPAPAGTT----------AIPGLIPDLVAGTP-----WPRWALIAGALAAGVLLVSCLLCAA--CCCCRRHRKKPRDKESVGLGSARGTTTT---------HLVQPDVDGLESS--------PGDAQQWGCLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQ-PEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * * : :: : : : . . * * .:::: : * : .* * . .*: ***. * : .: : .:*** : .* * *.* :: :* : .* . :::*.**. :: :*:.:: : .:: : . : * *::*::* ******::.:**: ::**:.*: * ::*:**: : :: :*:**: *: * **:**:*:* :. *:* .: . .::*:*: ", "identical_positions": 59, "similar_positions": 96, "identity": "11.92%" }, { "cls_id": "homologset.agr.FB:FBgn0004244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18506-1", "uniprot_id": "GBRD_RAT", "id": "P18506-1", "name": "Gamma-aminobutyric acid receptor subunit delta", "aln": "----------------MDVLGWLL------------------LPLLLLCTQPHHGARAMN-DIGDYVGSNLEISWLPNLDGLMEGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHT---NETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYR--FTTELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRA-SAIKALDVYFWICYVFVFAALVEYAFA------------HFN-ADYRKKRKAKVKVTKPRAEMDVRN---AIVLFSLSAAGVS----------------------------------------QELAISRRQGR----VPGNLMGSYRSVEVEA---KKE----------GGSRPGGPGGIRSRLKP-------------------------------------------------IDADTIDIYARAVFPAAFAAVNIIYWAAYTM---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22933-1", "uniprot_id": "GBRD_MOUSE", "id": "P22933-1", "name": "Gamma-aminobutyric acid receptor subunit delta", "aln": "----------------MDVLGWLL------------------LPLLLLCTQPHHGARAMN-DIGDYVGSNLEISWLPNLDGLMEGYARNFRPGIGGAPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHT---NETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPLDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYR--FTTELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRA-SAIKALDVYFWICYVFVFAALVEYAFA------------HFN-ADYRKKRKAKVKVTKPRAEMDVRN---AIVLFSLSAAGVS----------------------------------------QELAISRRQGR----VPGNLMGSYRSVEVEA---KKE----------GGSRPGGPGGIRSRLKP-------------------------------------------------IDADTIDIYARAVFPAAFAAVNIIYWAAYTM---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14764-1", "uniprot_id": "GBRD_HUMAN", "id": "O14764-1", "name": "Gamma-aminobutyric acid receptor subunit delta", "aln": "----------------MDAPARLL------------------APLLLLCAQQLRGTRAMN-DIGDYVGSNLEISWLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHT---NETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYR--FTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRA-SAIKALDVYFWICYVFVFAALVEYAFA------------HFN-ADYRKKQKAKVKVSRPRAEMDVRN---AIVLFSLSAAGVT----------------------------------------QELAISRRQRR----VPGNLMGSYRSVGVETGETKKE----------GAARSGGQGGIRARLRP-------------------------------------------------IDADTIDIYARAVFPAAFAAVNVIYWAAYAM---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TER6-1", "uniprot_id": "A0A8N7TER6_DANRE", "id": "A0A8N7TER6-1", "name": "Gamma-aminobutyric acid receptor subunit delta", "aln": "----------------MDALSLTV------------------KLFWLVLIGGDRRSRAMLSDIGDYVGTDIEISWLPNLDDLMKGYARNFRPGIGGPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWRDDRLSYNHT---NKTLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSSRITSTVACDMDLTKYPMDEQECMLDLESYGYSSEDIVYHWSESQKLIHGLDKLELSQFTITDYR--FVTEMMNFKSAGRFPRLSLRFQLRRNRGVYIIQSYMPSILLVAMSWVSFWISQSAVPARVSLGITTVLTMTTLMVSARSSLPRA-SAIKALDVYFWICYVFVFAALIEYAFA------------HYN-ADYSKKEKAKVKTNKN-AESMVKNGKQAMVLFSLSVAGMN----------------------------------------QGLLISNRQSRSHRASDAAAAAADPHEETETRSATSR----------RAQKESSEEKKCCKCKP-------------------------------------------------IDADTIDIYARAVFPFTFAVVNVIYWVAYTM---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O09028-1", "uniprot_id": "GBRP_RAT", "id": "O09028-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-----------------MSYS---------------------LYLAFVCLNLLAQRMCIQGNQFNVEVSRSDKLSLPGFENLTAGYNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEG----NKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQY---FTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVA------------HYSSLQQMAVKD--RGPAKDSEEVNITN----IINSSISSFKRK----------------------------------------ISFAS-IEISG------DNVNYSDLTMKASDKFK--------------FVFREKIGRIIDYFTI-------------------------------------------------QNPSNVDRYSKLLFPLIFMLANVFYWAYYMYF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZW7-1", "uniprot_id": "GBRP_MOUSE", "id": "Q8QZW7-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-----------------MSYS---------------------LYLAFLCLSLLTQRTCIQGNQVNVEVSRSDKLSLPGFENLTAGYNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEG----NKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQY---FTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVA------------HYSSLQQMAVKD--RGPAKDSEEVNITN----IINSSISSFKRK----------------------------------------ISFAS-IEISG------DNVNYSDLTMKASDKFK--------------FVFREKISRIIDYFTI-------------------------------------------------QNPSNVDRYSKLLFPLIFMLANVFYWAYYMYF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00591-1", "uniprot_id": "GBRP_HUMAN", "id": "O00591-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-----------------MNYS---------------------LHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG----NKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERY---FTLVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVA------------HYSSLQQMAAKD--RGTTKEVEEVSITN----IINSSISSFKRK----------------------------------------ISFAS-IEISS------DNVDYSDLTMKTSDKFK--------------FVFREKMGRIVDYFTI-------------------------------------------------QNPSNVDHYSKLLFPLIFMLANVFYWAYYMYF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BL14-1", "uniprot_id": "A0A8M2BL14_DANRE", "id": "A0A8M2BL14-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "---MICISDLHSYQSSGLHYHRML------------------LNLLFWTSLFLLITNGERGFYGNQYGEWNDSQLQPTIQKLMKGYNRYLRPNFNEGPVEIGMSLDIASIDAISEINMDYTATIFLRQRWRDSRLIFPG----NESLSLDGRLVSLLWIPDTFIPDSKRSFLHDVTVENRLIRIFSNGTVLYALRITATIACNMDLTKYPMDRQECTLQLESWGYNLEDVVFYWTRGNDSVKGLDTLRLAQYSVESY---YTSVTKAVYETGLYPKLILHFALRRNVLFFILETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKAIDVYLGICFTFIFGALLEYACA------------HFCTMQHQTIIDVQRELLKEFEESNGTT----HLVSSMSPRKMK----------------------------------------TEDSTKQEKPE------QTVTCEENEAVEQTKEKGCG----------LTTVKQMSRRAASMMSV-------------------------------------------------ENPHNIDRHARILFPMAFLLINIFYWLYYLLF--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BKD0-1", "uniprot_id": "A0A8M2BKD0_DANRE", "id": "A0A8M2BKD0-1", "name": "", "aln": "----------------MESIG-KT------------------PHIFLLCPLIVAVACAQS-----IRDPSNMPVVKDTVDRLMKGYDIRLRPDFGGAPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEI---PLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDGAVSGVERIELPQFSIVDYK--LISKNVVFS-TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI-PYVKAIDMYLMGCFVFVFLALLEYAFVN---------YIFFGRGPQRQKKAAEKAATANNEKLRPDPNKMTPDDIRLTTVEMK----------------------------------------NEMGPSDLSRGLGDPRSTMLAYDSSTLQYRRAAMARQNYGHSALERHATQKKSRLRRRASQLKVNIPDL--------------------------------------------SDVNSIDKWSRMIFPTLFSFFNIVYWLYYVH---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8MPY1-1", "uniprot_id": "GBRR3_HUMAN", "id": "A8MPY1-1", "name": "Gamma-aminobutyric acid receptor subunit rho-3", "aln": "---MVLAFQLVSFTYIWIILKPNVC------------AASNIKMTHQRCSSSMKQTCKQETRMKKD-DSTKARPQKYEQLLHIEDNDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTA--NKSMTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFS--ASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQV-SYLKAVDVYLWVSSLFVFLSVIEYAAVN-----------YLTTVEERKQFKKTGKISRMYNIDAVQA---MAFDGCYHDSEID----------------------------------------MDQTS---LSLNSE-DFMRRKSICSPSTDSS----------------RIKRRKSLGGHVGRIIL-------------------------------------------------ENNHVIDTYSRILFPIVYILFNLFYWGVYV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50573-1", "uniprot_id": "GBRR3_RAT", "id": "P50573-1", "name": "Gamma-aminobutyric acid receptor subunit rho-3", "aln": "---MVLAFWLAFFTYTWITLML---------------DASAVKEPHQQCLSSPKQTRIRETRMRKD-DLTKVWPLKREQLLHIEDHDFSTRPGFGGSPVPVGIDVQVESIDSISEVNMDFTMTFYLRHYWKDERLSFPSTT--NKSMTFDRRLIQKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEEDLMLYWKHGNKSLNTEEHISLSQFFIEEFS--ASSGLAFYSSTGWYYRLFINFVLRRHIFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIVTGVSASMPQV-SYVKAVDVYMWVSSLFVFLSVIEYAAVN-----------YLTTVEEWKQLNRRGKISGMYNIDAVQA---MAFDGCYHDGETD----------------------------------------VDQTS---FFLHSEEDSMRTKFTGSPCADSS----------------QIKR-KSLGGNVGRIIL-------------------------------------------------ENNHVIDTYSRIVFPVVYIIFNLFYWGIYV----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47742-1", "uniprot_id": "GBRR2_RAT", "id": "P47742-1", "name": "Gamma-aminobutyric acid receptor subunit rho-2", "aln": "---MPYFMRLALFLFCLMALVESR------------------KPRRKRWTGHLETSKP-SHLYKKNLDVTKIRTGKPRPLLRVEDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWRDERLAFPSSS--NRSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFH--TTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDHRAVPARVSLGIMTVLTMSTIITGVNASMPRV-SYIRAVDIYLWVSFVFVFLSVLEYAAVN-----------YLTTVQEQKERKLRDKFPCTCGMLHSRT---MTLDGSYSESEAN----------------------------------------SLAGYPRSHILPEEERQDKIVVHLALNSELT----------------SSRKKGLLKGQMGLYIF-------------------------------------------------QNTHAIDKYSRLIFPAFYIVFNLIYWSVFS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56476-1", "uniprot_id": "GBRR2_MOUSE", "id": "P56476-1", "name": "Gamma-aminobutyric acid receptor subunit rho-2", "aln": "---MPYLMRLALVLFCLMALVESR------------------KPRRKRWTGLLETSKP-SHLYKKNLDVTKMRPGKPRPLLRVEDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWRDERLAFPSSS--NKSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFH--TTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDHRAVPARVSLGIMTVLTMSTIITGVNASMPRV-SYIRAVDIYLWVSFVFVFLSVLEYAAVN-----------YLTTLQEQKERKFREKLPCMCGMLHSRT---MMLDGSYSESEAN----------------------------------------SLAGYPRSHILPEEERPDNIVVHLALNSELT----------------SSRKKGLLKGQMGLYIF-------------------------------------------------QNTHAIDKYSRLIFPAFYIVFNLIYWSVFS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28476-1", "uniprot_id": "GBRR2_HUMAN", "id": "P28476-1", "name": "Gamma-aminobutyric acid receptor subunit rho-2", "aln": "---MPYFTRLILFLFCLMVLVESR------------------KPKRKRWTGQVEMPKP-SHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS--NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFH--TTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRV-SYVKAVDIYLWVSFVFVFLSVLEYAAVN-----------YLTTVQERKERKLREKFPCMCGMLHSKT---MMLDGSYSESEAN----------------------------------------SLAGYPRSHILTEEERQDKIVVHLGLSGEAN----------------AARKKGLLKGQTGFRIF-------------------------------------------------QNTHAIDKYSRLIFPASYIFFNLIYWSVFS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50572-1", "uniprot_id": "GBRR1_RAT", "id": "P50572-1", "name": "Gamma-aminobutyric acid receptor subunit rho-1", "aln": "-MLAVRNMKFGIFLLWWGWVLAAESTVHWPGREVHEPSKKGSRPQRQRRGAHDDAHKQGSPILKRSSDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTN--NLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFH--TTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRV-SYIKAVDIYLWVSFVFVFLSVLEYAAVN-----------YLTTVQERKERKLREKISCTCGLPQPRG---VMLDSSYSDGEVN----------------------------------------DLGGY----MPENGEKPDRMMVQLTLASERG----------------SPQRKSQRGSYVSMRI---------------------------------------------------NTHAIDKYSRIIFPAAYILFNLIYWSIFS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56475-1", "uniprot_id": "GBRR1_MOUSE", "id": "P56475-1", "name": "Gamma-aminobutyric acid receptor subunit rho-1", "aln": "-MLAVQNMKFGIFLLWWGWVLAAESTAHWPGREVHEPSRKGSRPQRQRRGAHDDAHKQGSPILRRSSDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSSN--NLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFH--TTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRV-SYIKAVDIYLWVSFVFVFLSVLEYAAVN-----------YLTTVQERKERKLREKISCTCGLPQPRG---VMLDSSYSDGEVN----------------------------------------DLGGY----MPENGEKPDRMMVQLTLASERG----------------SPQRKGQRGSYVSMRI---------------------------------------------------NTHAIDKYSRIIFPAAYILFNLIYWSIFS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24046-1", "uniprot_id": "GBRR1_HUMAN", "id": "P24046-1", "name": "Gamma-aminobutyric acid receptor subunit rho-1", "aln": "-MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKG-RPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTN--NLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFH--TTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRV-SYIKAVDIYLWVSFVFVFLSVLEYAAVN-----------YLTTVQERKEQKLREKLPCTSGLPPPRT---AMLDGNYSDGEVN----------------------------------------DLDNY----MPENGEKPDRMMVQLTLASERS----------------SPQRKSQRSSYVSMRI---------------------------------------------------DTHAIDKYSRIIFPAAYILFNLIYWSIFS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25123-2", "uniprot_id": "GBRB_DROME", "id": "P25123-2", "name": "Gamma-aminobutyric acid receptor subunit beta", "aln": "MSDSKMDKLARMAPLPRTPLLTIWLA----------------INMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRP-GVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG---HRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKI-SYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48168-1", "uniprot_id": "GLRB_MOUSE", "id": "P48168-1", "name": "Glycine receptor subunit beta", "aln": "---MKFSLAISFFILMSLLFEDACAK----------------EKSSKKGKGKKKQYLCPSQQSPEDLARVPPNSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSG--DPVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKV-SYVKALDVWLIACLLFGFASLVEYAVVQVMLN-----NPKRVEAEKARIAKAEQADGKGGNAAKKNTVNGTGTPVHISTLQVG-----------------------------------------ETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKP------IEVNNGLGKPQAKNKKPP-----------------------------PAKPVIPTAAKR------------IDLYARALFPFCFLFFNVIYWSIYL----------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .: : : : : *:. :.* *:: .:::: * * ** : .. . :* ** :: . * : * .* * :: : .* : . *:: : * ::: :*:* * * :::**:.* *: * . . : *.*: : :* : : : : * ::: * *: ::. :**:***:. : .**. :*: :**:::: :*. ::::*::: . : * :::*** . :* :: :** : *:.** : ", "identical_positions": 56, "similar_positions": 102, "identity": "8.93%" }, { "cls_id": "homologset.agr.FB:FBgn0004360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9D3-1", "uniprot_id": "M0R9D3_RAT", "id": "M0R9D3-1", "name": "Protein Wnt", "aln": "-MTRK--ARRCLGHLFLSLGIVYLRIG---DFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHR----DEGWKWGGCSADIRYGIGFAKVFVDAREIKQ---NARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRK-------PMDTDLVYIEKSPNYCEEDPVT-GSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24383-1", "uniprot_id": "WNT7A_MOUSE", "id": "P24383-1", "name": "Protein Wnt-7a", "aln": "-MTRK--ARRCLGHLFLSLGIVYLRIG---GFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHR----DEGWKWGGCSADIRYGIGFAKVFVDAREIKQ---NARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRK-------PMDTDLVYIEKSPNYCEEDPVT-GSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00755-1", "uniprot_id": "WNT7A_HUMAN", "id": "O00755-1", "name": "Protein Wnt-7a", "aln": "-MNRK--ARRCLGHLFLSLGMVYLRIG---GFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHR----DEGWKWGGCSADIRYGIGFAKVFVDAREIKQ---NARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRK-------PMDTDLVYIEKSPNYCEEDPVT-GSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56706-1", "uniprot_id": "WNT7B_HUMAN", "id": "P56706-1", "name": "Protein Wnt-7b", "aln": "-MHRN--FRKWIFYVFLCFGVLYVKLG---ALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQ----AEGWKWGGCSADVRYGIDFSRRFVDAREIKK---NARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQK-------PMETDLVYIEKSPNYCEEDAAT-GSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28047-1", "uniprot_id": "WNT7B_MOUSE", "id": "P28047-1", "name": "Protein Wnt-7b", "aln": "-MHRN--FRKWIFYVFLCFGVLYVKLG---ALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGIDECQHQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQ----AEGWKWGGCSADVRYGIDFSRRFVDAREIKK---NARRLMNLHNNEAGRKVLEDRMKLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQK-------PMETDLVYIEKSPNYCEEDAAT-GSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K3B7-1", "uniprot_id": "A0A0G2K3B7_RAT", "id": "A0A0G2K3B7-1", "name": "Protein Wnt", "aln": "MLLLS--PRSALVSVYCPQIFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGIDECQHQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQ----AEGWKWGGCSADVRYGIDFSRRFVDAREIKK---NARRLMNLHNNEAGRKVLEDRMKLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQK-------PMETDLVYIEKSPNYCEEDAAT-GSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28465-1", "uniprot_id": "WNT2_DROME", "id": "P28465-1", "name": "Protein Wnt-2", "aln": "-MWKI--HNKLLIYILWIMEIR-----------LVSSFTSVMLCGRIPGLTPGQRNMCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKATPTGGGTPDEPWKWGGCSADVDFGMRYARRFMDARELER---DSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMLKYQKAKTVQAVKGKRGLRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQT-GSQGTSGRTCQRTGHGPQSCDLLCCGRGHNTQHIRRTTQCRCQFRWCCEVKCDECDESYEEFTCK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9QXQ5-1", "uniprot_id": "WNT4_RAT", "id": "Q9QXQ5-1", "name": "Protein Wnt-4", "aln": "-MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRHGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGDLEKCGCDRTVHGVSPQ------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSS-RALVPRNAQFKPHTD----------EDLVYLEPSPDFCEQDMRS-GVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAHVELAERCGCRFHWCCFVKCRQCQRLVEMHTCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22724-1", "uniprot_id": "WNT4_MOUSE", "id": "P22724-1", "name": "Protein Wnt-4", "aln": "-MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQ------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSS-RALVPRNAQFKPHTD----------EDLVYLEPSPDFCEQDIRS-GVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCGCRFHWCCFVKCRQCQRLVEMHTCR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56705-1", "uniprot_id": "WNT4_HUMAN", "id": "P56705-1", "name": "Protein Wnt-4", "aln": "-MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQ------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSS-RALVPRNAQFKPHTD----------EDLVYLEPSPDFCEQDMRS-GVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47793-1", "uniprot_id": "WNT4A_DANRE", "id": "P47793-1", "name": "Protein Wnt-4a", "aln": "-MSSEYLIRSLLMLFLALFSANASNWLYLAKLSSVGSISDEETCEKLRGLIQRQVQICKRNVEVMDAVRRGAQLAIDECQYQFRNRRWNCSTLESVPVFGKVVTQGTREAAFVYAISAASVAFAVTRACSSGELDKCGCDRNVHGVSPE------GFQWSGCSDNIAYGVAFSQSFVDIRERSKGQSSNRALMNLHNNEAGRKAILNHMRVECKCHGVSGSCEVKTCWKAMPPFRKVGNVIKEKFDGATEVELRKVGTT-KVLVPRNSQFKPHTD----------EDLVYLDPSPDFCEHDPRTPGIMGTAGRFCNKTSKAIDGCELMCCGRGFHTEEVEVVDRCSCKFHWCCYVKCKQCRKMVEMHTCR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * :: * :: ** * :*: :.: : .* *:. :***.*** ***** : . **.: : .:****:.*** :*..*.*:* **: *::. **** :. ::*.*** :: :*: ::: *:* ** .: . * *******.***. : :: :********** **** ::* ** :* : *:: * *: : : . : : . :*:*:: **::**.. : * ** ** *::*. ..*: :*****.:* . . :* *:*:*** *** * . * .**:", "identical_positions": 113, "similar_positions": 97, "identity": "30.54%" }, { "cls_id": "homologset.agr.FB:FBgn0004362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11632-1", "uniprot_id": "NHP6A_YEAST", "id": "P11632-1", "name": "Non-histone chromosomal protein 6A", "aln": "----------------------MVTPREPKKRTTRKKKDPNAPKRALSAYMFFANENRDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELYNATLA--------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q05783-1", "uniprot_id": "HMGD_DROME", "id": "Q05783-1", "name": "High mobility group protein D", "aln": "--------------------------------------MSDKPKRPLSAYMLWLNSARESIKRENPGIKVTEVAKRGGELWRAMK--DKSEWEAKAAKAKDDYDRAVKEFEANGGSSAANG----------------GGAKKRAKPAKKVAKKSKKEESDEDDDDESE---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02486-1", "uniprot_id": "ABF2_YEAST", "id": "Q02486-1", "name": "ARS-binding factor 2, mitochondrial", "aln": "MNSYSLLTRSFHESSKPLFNLASTLLKASKRTQLRNELIKQGPKRPTSAYFLYLQDHRSQFVKENPTLRPAEISKIAGEKWQNLEADIKEKYISERKKLYSEYQKAKKEFDEKLPPKKPAGPFIKYANEVRSQVFAQHPDKSQLDLMKIIGDKWQSLDQSIKDKYIQEYKKAIQEYNARYPLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***. ***::: :. *. . *** : ::.* ** *: : *. : :: . *: : :: . ", "identical_positions": 16, "similar_positions": 25, "identity": "8.74%" }, { "cls_id": "homologset.agr.FB:FBgn0004363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P81155-1", "uniprot_id": "VDAC2_RAT", "id": "P81155-1", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "-------------MAECCVPVCQRPICIPPPYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTN--CTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60930-1", "uniprot_id": "VDAC2_MOUSE", "id": "Q60930-1", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "-------------MAECCVPVCPRPMCIPPPYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTN--CTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45880-3", "uniprot_id": "VDAC2_HUMAN", "id": "P45880-3", "name": "Non-selective voltage-gated ion channel VDAC2", "aln": "-------------MATHG-QTCARPMCIPPSYADLGKAARDIFNKGFGFG-LVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTN--CTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60932-1", "uniprot_id": "VDAC1_MOUSE", "id": "Q60932-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "------------MCSFFLVLLLWQNMAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNS--NTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2L0-1", "uniprot_id": "VDAC1_RAT", "id": "Q9Z2L0-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "-------------------------MAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNS--NTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21796-1", "uniprot_id": "VDAC1_HUMAN", "id": "P21796-1", "name": "Non-selective voltage-gated ion channel VDAC1", "aln": "-------------------------MAVPPTYADLGKSARDVFTKGYGFG-LIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNS--NTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60931-1", "uniprot_id": "VDAC3_MOUSE", "id": "Q60931-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "-------------------------MCNTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYRRDCFSLGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNERIETSINLAWTAGSN--NTRFGIAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFNAGGHKVGLGFELEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y277-1", "uniprot_id": "VDAC3_HUMAN", "id": "Q9Y277-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "-------------------------MCNTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSN--NTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1Z0-1", "uniprot_id": "VDAC3_RAT", "id": "Q9R1Z0-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "-------------------------MCSTPTYCDLGKAAKDVFNKGYGFG-MVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLIFTQKWNTDNTLGTEISWENKLAEGLKLTVDTIFVPNTGKKSGKLKASYRRDCFSVGSKVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLCQNNFALGYKAEDFQLHTHVNDGTEFGGSIYQRVNEKIETSINLAWTAGSN--NTRFGIAAKYRLDCRTSLSAKVNNASLIGLGYTQSLRPGVKLTLSALVDGKNFNAGGHKVGLGFELEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BEA1-1", "uniprot_id": "A0A8M2BEA1_DANRE", "id": "A0A8M2BEA1-1", "name": "Non-selective voltage-gated ion channel VDAC3", "aln": "MSEKGHKQKGSSETCHHCKPKTCANMAVPPAYADLGKSAKDIFSKGYGFG-TVKLDLKTKSQSGVEFTTGGSSNTDTGKAAGNLETKYKVKELGLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDLDFDLAGPTVHAAAVLGYEGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNGQLETAVNLAWTAGSN--NTRFGIAAKYQLDKDSSVSAKVNNASLVGVGYTQSLRPGVKLTLSALIDAKNFNAGGHKVGMGFELEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94920-1", "uniprot_id": "VDAC_DROME", "id": "Q94920-1", "name": "Voltage-dependent anion-selective channel", "aln": "--------------------------MAPPSYSDLGKQARDIFSKGYNFG-LWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTS--NTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40478-1", "uniprot_id": "VDAC2_YEAST", "id": "P40478-1", "name": "Non-selective voltage-gated ion channel 2", "aln": "--------------------------MALRFFNDISRDVNGLFNRDFFHTNPLSLNISTTTENGVNFTLKAKQGVTEGPIQTSVEGRFYDRKEGVSLSQSWSNQNRLNTRIEFS-KIAPGWKGDVNAFLTPQS-IKNAKFNLSYAQKSFAARTSIDI-LQPKDFVGSVTLGHRGFVGGTDIAYDTAAGLCARYAMSIGYLAREYSFILSTNNRQCATASFFQNVNRYLQVGTKATLQSKTS-SNMNIEFVTRYVPDSISQVKAKIADSGLTTLSYKRNLNKDISLGVGMSFNALQLTEPVHKFGWSLSFSP", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04840-1", "uniprot_id": "VDAC1_YEAST", "id": "P04840-1", "name": "Non-selective voltage-gated ion channel 1", "aln": "--------------------------MSPPVYSDISRNINDLLNKDFYHATPAAFDVQTTTANGIKFSLKAKQPVKDGPLSTNVEAKLNDKQTGLGLTQGWSNTNNLQTKLEFA-NLTPGLKNELITSLTPGV-AKSAVLNTTFTQPFFTARGAFDLCLKSPTFVGDLTMAHEGIVGGAEFGYDISAGSISRYAMALSYFAKDYSLGATLNNEQITTVDFFQNVNAFLQVGAKATMNCKLPNSNVNIEFATRYLPDASSQVKAKVSDSGIVTLAYKQLLRPGVTLGVGSSFDALKLSEPVHKLGWSLSFDA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:.: ..::.:.: . :::.*.: .*::*. . .:* : . *: :.: *.. * * *.: :: * * . : * *.. :: : : . .:: : . . .:...* :.* : :: . :::.* : :: : *: .::*.. ::.. : : . .: : ::* * : . **: ::. :.* : *. .:.* :. .:. ... **.* .:.:. ", "identical_positions": 29, "similar_positions": 117, "identity": "9.32%" }, { "cls_id": "homologset.agr.FB:FBgn0004367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z822-1", "uniprot_id": "D3Z822_RAT", "id": "D3Z822-1", "name": "Serine/threonine-protein kinase ATR", "aln": "MGDHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVALELVKKTDTQPTSVMLLDFIQHIMKSSPLMFVN-VNGSQGQNEAKDSCIEFSHWIITRLLRIAATPSCHMLHKKICEVICSLLFLFKSKNPAIFGVLTRELLYLFEDLIYLHKRNAVGDVMEWPVVVSRFLSRLDEHMGCLQPAPLQFMNMQNVEFIEVTLLMVLIHIVPTVFFRRQELLLWQIGCALLEHGSPKIRSLAISLLTELFELGGLPAQPASTFFSLFLELLQHLIGMDADQLKLYEEPLSKLVKTLFPFEAEAYRNIEPVYLNVLLEKLRVMFEDRVLMRLKSDLLKAALCHLLQYFLTFVPAGYESALQVRKVYVTDICRALVDVLG-VQTHVGYLLGPFYAALKMESTEIIERIQCQAQQ-ENLRGSNDGVSPKRRRLSSSLSSYKRPSRQSEEINHVDMDKKSILWNVLKQKAESLQISLECGTLKNSVAEALEGITIVLQLTALCTVHCSHQDMDGHNAKDCQHKYKKKPPVVITWMSLDFYTKVLKSCKSLLES-VQKHELELVIDSVVRIYDALMYIQVKSSFQDHVLEELCGMLSLPWIYSYSDDNSLKMTTFATNLLRLSQRVWESYSPQAQSQCVFLLTLFPKRIFLDWRTTVYNWALKSSHEVIRTSCVKGFFILLQQE--NSCNQIPKMLIDRVKDDSHVVKKEFASVLGQLVCTLHGMFYLTSSSVEPFFGP--VDLFCKNLKATSQHECSSSQVKASVCKPFLFLLTKNTPSPVKLAFIDNLHHLCKHLDFQEDETEVKAVLGTLLNLMEDPDKDVRIAFSGNIKYILESLNSEDGFIKELFVLRMKEAYTHAQISRSNELKDTLILTTGDIGRAAKGDLIPFALLHLLHCLLSKS-ASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSTPCQTAEMRKQHVAHHREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDITSPELMADYLQPKLLGILAFFNMQLLSSSVG-IEDKKMALTSLMSLMKLMGP-KHVSSVRVKMMTTLRTGLRFKD-DFPELCCRAWDCFVRCLDHAYLGPLLSHVIVALLPLIQMQP--KETAAIFHYLIIENRVAVQDFLHEIYFLPDHP----------ELEKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQ-EKLIKYATDSETVEPVISQLVTVILKG---CQDANSQARLLCGECLGELGAIDPGRLDFSTT-ETQGKDFTFVTGVEDLSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQSNGPGHQLWK---RFPEHVREILEPHLNTRYKSSQKSTDWSGVTKPIYLSKLGN-NFAEWSSSWAGYLITKVRDNLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCSQ-EDQQEVYAEIMAVLKHDDQ-------------------HAISTQDSASDLCQLSTQTVFSMLDHLTQWARHK-------FQALNAEKLAQNKPKG------VSSVNFEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITE---KKQNIQKHLGFLQKLYAAMHEPDGVAGVSAIRKAE--PSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSE--WTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDTTAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEFIVRLHMLCELEHSLKPLFHKFPGDSCN-------EDSLNWAARLEMTQNSYRAKEPILALRRALLSLNKR---------PDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFP---ENKSPTESKHMLIHGRATLLVGRFMEETANFESNAIMKKYKDVTLFLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQG---DLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDFGAKAYEWEKGGRSDRLQMRNDLAKINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILTKAIHMKKSLEKFVGDATRLTDKLLELCNKSVDGSNSTLSMSTHFKMLKKLVEDPTFSEILIPLQSVMIPTLPSILGAHAN-----------HDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQEILLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPPNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKK8-1", "uniprot_id": "ATR_MOUSE", "id": "Q9JKK8-1", "name": "Serine/threonine-protein kinase ATR", "aln": "MGDHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVALELVKKTDAQPTSVMLLDFIQHIMKSSPLMFVN-VNGSQGQNEAKDSCIEFSHWIITRLLRIAATPSCHMLHKKICEVICSLLFLFKSKNPAIFGVLTRELLYLFEDLIYLHKRNAVGEVMEWPVVVSRFLSRLDEHMGCLQPAPLQFMNVQNVEFIEVTLLMVLIHIVPTVFFRRQELLLWQIGCALLEHGSPKIRSLAISLLTELFELGGLPAQPASTFFSLFLELLQHLVGMDADQLKLYEEPLSKLLKTLFPFEAEAYRNIEPVYLNVLLEKLSVMFEDRVLMRLKSDLLKAALCHLLQYFLTFVPAGYESALQVRKVYVTNICRALVDALG-VQKHVGYLLGPFYAALKMESKEIIERIQCQAQQ-ENLSGNNDEVSPKRRKLSSSLSSYKKPSRQPEEIIHVDMDKKSILWNVLKQKAESLQISLECGTLKNSVAEALEGITVVLQLTALCTVHCSHQDMDGHNVKDHQHKYKKKPPVVVTWMSLDFYTKVLKSCRSLLES-VQKLELELVIDSMVRICDALMYMQVKSSFKDHVLEELCGMLSLPWIYSYSDDNSLKMTTFATNLLPLSQRVWDSYSPQAQSKCVFLLTLFPRRIFLEWRTAVYNWALKSSHEVIRASCVKGFFILLHQQ--NSCNQIPKMLVDRVKDDSDMVKKEFASVLGQLVCTLHGMFYLSSS-VEPCFEH--MDLFSKNLKATSQHECSSSQVKASTCKPFLFLLTKNTPSPVKLAFIDNLHHLCKHLDFQEDEREVKAVLGTLLNLMEDPDKDVRIAFSGNIKYILESLNSEDGFVKELFVLRMKEAYTHAQIARNNELKDTLILTTGDIGRAAKGDLIPFALLHLLHCLLSKS-ASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSAPCQSSEIRKQDVAHHREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVSRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDITSPELMADYLQPKLLGILAFFNMQLLSSSVG-IEDKKMALTSLMSLMKLMGP-KHVSSVRVKMMTTLRTGLRFKD-DFPELCCRAWDCFVRCLDHAYLGPLLSHVIVALLPLIHMQP--KETAAIFHYLIIENRDAVQDFLHEIYFLPDHP----------ELEKIKAVLQEYRKETSETTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQ-EKLIKYATDSETVEPVISQLVTVILKG---CQDANSQARLLCGECLGELGAIDPGRLDFSTT-ETQGKDFTFVTGVEDLSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQSNGPGYQLWK---RFPEHVREILEPHLNTRYKSSQKSTDWSGVTKPIYLSKLGN-NFAEWSSSWAGYLITKVRDNLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQ-EDQQEVYAEIMAVLKHDEQ-------------------HAISTQDSASDLCQLSTQTVFSVLDHLTQWARHK-------FQALNAEKLAQNKPKG------VSNVNFEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITE---KKQNIQKHLGFLQKLYAAMHEPDGVAGVSAIRKAE--PSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSE--WTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDTTTFYDTLKLVRAEQIVPLSAASFERGSYQRGYEFIVRLHMLCELEHSLKPLFRKSPGDSCN-------EDSLNWGARLEMTQNSYRAKEPILALRRALLSLNKR---------PDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFP---ENKSPSESKHMLIHGRATLLVGRFMEETANFESNAVMKKYKDVTLFLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQG---DLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDFGAKAYEWEKGGRSDRLQMRNDLAKINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILTKAIHMKKSLEKFVGDATRLTDKLLELCNKSVDGSNSTLSMSTHFKMLKRLVEDPTFSEILIPLQSVMIPTLPSVLGAHAN-----------HDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQELLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEGSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13535-1", "uniprot_id": "ATR_HUMAN", "id": "Q13535-1", "name": "Serine/threonine-protein kinase ATR", "aln": "MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVN-VSGS---HEAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLSQLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAGYESALQVRKVYVRNICKALLDVLG-IEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQ-ENLSSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYSGLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFYTKVLKSCRSLLES-VQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQ--NSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHGMFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS-ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVG-IEDKKMALNSLMSLMKLMGP-KHVSSVRVKMMTTLRTGLRFKD-DFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQP--KETAAIFHYLIIENRDAVQDFLHEIYFLPDHP----------ELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQ-EKLIKYATDSETVEPIISQLVTVLLKG---CQDANSQARLLCGECLGELGAIDPGRLDFSTT-ETQGKDFTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGHQLWR---RFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGS-NFAEWSASWAGYLITKVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQ-EDQQEVYAEIMAVLKHDDQ-------------------HTINTQDIASDLCQLSTQTVFSMLDHLTQWARHK-------FQALKAEKCPHSKSNRNKVDSMVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITE---KKQNIQEHLGFLQKLYAAMHEPDGVAGVSAIRKAE--PSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSE--WTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEHSIKPLFQHSPGDSSQ-------EDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKR---------PDYNEMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVELCFP---ENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHFYLAKYYDKLMPMVTDNKMEKQG---DLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTKAYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANH--------ASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEF8-1", "uniprot_id": "A0A8N7TEF8_DANRE", "id": "A0A8N7TEF8-1", "name": "Serine/threonine-protein kinase ATR", "aln": "-MEQGLEMSAMIPALQELASASSVEYNQAVQKPRQILCQFIDRILTDVDVVALELCKKSSSEPACVMLLDFVQHIIKSSSLMFINPACLSDHFKNSENSCTDFTKWIINRLLRIAACPECEDLHMKISSVICSLLHLFRAKAPVVFSLFSTELICLIQDLV--HKNLMTRPSPQWPVVVERFSIKSGESAVYLTPTILQLSSLSSTQALLATSLRVLTDVIQGLFFPREVGIIWDSTCLMLSNGSPKLKAVSMVLLTRIVTLGGFPEDHSQPFFSAFLHVLDSLPAFDESELGVFSREFQQLSRCIFQHEEGAHSRFERVHLNMLMERLEKLVVIGALEHLKVKEVKATLCEVFCFILGFVPPGYECALQIRKERVAAICKALIKTIGTKDQHEQSLEGYLYAALKTDAIAAMQDVQASVSDPADPRMYEEELPAKRPNLSLPTQLRSRDKTQP---MQVDMKSRSEVWAAVDCRLEELLTQMRNHTVS-QCVSAVQGLAVIFHLAALCSEHSLKGPQRG------EKSSESSVVAQLIWLKPQMLAQVVESCRTVLANNYNEEHLEHLVEGIVRILDAVLYLSTNSESDKSFHRNICALLSVPWVLEHSSQSVYQTASFPASLIALSQKLAPVYNAQTRAHCVFLLAPLSKSVCGDWRSSVYRWALQSKSEAERASAVRGFPILLHQLGVKSNSLIHEALLNRLQDSSTEVKTELAGITGQLACCLSESSQLQFP-QETMPSH---QLLCSGLSISDFHSSQTSSIGTSILTPFLQLLKPVEDMKVKQAFIKNIRHLFKHVDLGNTDPDTKALVNALVNLIEDPDQEVRIMFGQNIKNLLEFWNG-NGFLKELLVSRLKEAYTNAKTSRNNELKNTLILTTGEIGRAAEGNLVSFALLRLLHCLLSKS-NPVSVAAYTEIQALATCRDLKLQSFFSQYRNPICQFLVESLHSRHVTALRCTPDQSSEALQEEAAHQRELALDILSHVAHVFDFPDLNRFLNRTLQVLLPFLAAKASPTASALIRTIAKQLNVNRREMLINNFKYIFSHLVCSCSKEELERAFHYLKNETEIELGSLLRQDFQGLHNELLLRLGEHYQQVFNGLAILASFASSDDPYQGPREITTPGCMADYLQPKLLGILAFFNMQLLSSSAGEKEKKKMALNSLMSLMKLMGP-KHISSVRVKMMTTLRTGLRYKD-DFPELCCRTWDCFVRCLDPSYLGPLLSHVIVALLPLISIQP--KETAVIMHYLIVENREEVQDFLHEIYFLPDHP----------ELKIIHKVLQDYRKQTSKSTDMQAALQLSMRAIQHENVDVRIHALTSLKEMIYKNQ-DALLKHVLDSEMVEPVISQLVTVLLRG---CQDVNTEARLLCGECLGELGAIDPGRLDLSPA-DTQGTGSTFVSGIDDPNFAYELLTELTRAFLAYADDVRAQDAAAYAMQELLSLFECREGRTDSSGRRLWR---RFPEQVQEILEPHLNTRYKSSQKVVNWSKLKKPIYLSSRGS-KFSDWSATWAGYLISKVRHELAGKVFNCCSFIIKHDYKVTIYLLPHILVYVLIGCTQ-EEQREVTEEIMAVLKEGDP-------------------RLVRLQENASSLSQLSTQTVFSMLDHLTQWSRHK-------LQTLSTNKRTGKNAREQ---PPATGPENSEYQSVVAFLNSIPQDVLAKASFRSRAYTRAVMHFESFIRE---KKQNIQDHLSFLQTLYAAMHEPDGVRGVNALRKEE--PSLREQILEHESIGLLRESTACYDRAIQLEPDQLAHYHGVMNSMLGLGQLSTVITQVNGVLASRPR--WKSDLNAYRVEAAWKLSKWDLVEDYLASDCKSSTWGVRLGQMLLAAKKQDSEAFYEKLKIARKEQVVPLSAASFECGTYQRGYEYIVRLHMLCELEHVFTELQKESSEAGRSKKP----EPKLNWDAHLLMTQNSFRAKEPVLALRRALLSLSKG---------SSCEEQVGECWLQSARVARRAGHHQTAFNALLNAENSHLSELFIEKAKWLWSKGDVHQALIVLQKGVQQCFP---DDQTLTDPKRIQVKGNAMLLVGRYMEETANFESNAIMKTYKDVTTLLPEWEDGNFYLAKYYDKVMPMVTDNKLERQG---NLIRYIVTYFGKALQFGNQYIYQAMPRMLTLWLDFGAKVYEFEKAGRSDRVQMRTELTKINSVISDHTSNLSPYQFLTAFSQLISRICHSSNEVFAVLMEIVAKVFLAYPQQAMWMMTAVSKSSYPTRMNRCKEILKKAISLNDSFMKFIGDANRLTDKLLELGNKPVDGNSSTLSMSVHFKMLKKLVEEPTFSQILIPLQSVLIPTLPSTGGANPK-----------HDAFPGHWVYLSGFDDTVEILASLQKPKKISLKGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKSLRKDAESRRRDLRIRTYAVIPLNEECGIIEWVNKTAGLRHILTKLYKEKGIYVSGTELKKLILPKTAPFQEKLKLHKDVLCARHPPVFHEWFLRTFPDPTSWYNSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVILRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGFSKTQVNESGEILNEKAKTHVLDIEQRLQGVIKNRNKVMGLPLSIEGHVHYLIQEATDDNLLCMMYLGWGPYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXG8-1", "uniprot_id": "ATR_DROME", "id": "Q9VXG8-1", "name": "Serine/threonine-protein kinase ATR", "aln": "----------MSTQRKDMWKLLYNHVNRNVSNFSGVYSVIEDILCQEPSLISCSLVRELHNKFQDTFLLWLLNKLAK--------------------------------CLSESPDSSECINLQRKILSSCCSNHPKLFERLVLAYVEAIEETHLQLSSLDLGQLSNERKP--AITVRIFRCDVECLQEFDPHCAIEDIKVPLEQADMYAKSLLEVLQHAHHIGYATHG-------------------DIFSGSLHQALLILKECDMDTKLASLNYCHNVLRSQSASS----------------WITNPDVGHYAQLTLEATAIMWSAVAKWLDMGCMTRQELKRLNITTKLLLEVLHMRARPAHHLGYLLLNEILS-----LPTAIELDDGLLETLSSYIQGQLEHSVVPLEQLVHLQQLMLSHWHCHPTHLVPILALMGLKQTEMRSGVVQVLTQSLVEILKKEEVLSKDWQKLIAILR-------------GFKQLEKLILSQSQHKIAEHEGHIDSSVLAMLPLQCEIIKVADTNWNNLSMQLVELESKCSADRR-----HIHLEICSLLMQITFIRHFLKTQT-QHQLLAILQRHLKLSYLCAIRLET---PSSVHTQMQSFYAQQYMRLFQSEETQEIFCSNLPQLYISGFIKPEQLMKALPTINNRSGRAQVIRLLLCSQPG---------KLSVFKVKDRIELYCPKCRPLPKKLPGIYLGKCKQQLPCPDFSSTN--LEMIANDLLFYPDFECIAQHLDLLCFEPNVILGLLRETEALQKVSVKVIGQLVSAMRVRSPEFLEQLAN--------------------------------------LVLAAIKAMLAKPLTEQNVLQQRSMLNVLTAIAHMEDNEIWLFHWFKMTFFFLVHTRSLVAQEAVLAATEMCASQGLQTIHLWNWYKR-------DALDLTVRLALNVYLLDGVRFTRSLRALTKMLGFTCVQEFTCKYHR----------LLTAMVLPHCIVNPLCKGVLVLIAKQMQKHIGTLFSISFLRIYTHVFLTEEPELANSCIELVVSCTQSSLQQLMNADVKQTVAELLIYFNRNPTFVMRSFQSLLQLSIG--SLEELSSQTANAEFANFIAERFLGVITYFESCLSEPSFE-KPLKEETLYSLGQIMRFVGS-QHVTQFRFKIIAMLSFVHTLQEPRLQRICLKIWHIFLHVVNVQELGPSLGRIVATLQPLLADNESVKQVNDLYEFIILRNASMLGTFITDLYFLDRMENVSPSIQKCIRRHTAHLDLKGLAEEENQSPPLVDQLRFLQKHITDECLQVRVYALQHLGDLFGRRR-PKLNSTILSELPLEPMLEQIVNVLMAG---CQHDDSQLQMASAKCLGELGAIDAS--YLPSN-YNFASPQHLPLNILSDDFAVLALTSLCRG-YQFQQNTKHVDSFSLAIQETLAICGISPKEQKK--VQLWQ---SLPARMRQLMEPMLHSCYTCVHRPS--TCLQQPLFGSHYSHNYYEEWAFLWASRLIDYLPSSGRRHLLSSYKPCIKRDSNMLSTFYPYILLHALLECTT-EQRNHIQEEFMAVLQANEESSSSVRGRQELGAIKENAFKQFESRKYAAGIKPLASTLVSDRKEDSSRVPRLAGKLCAELLDFLQRWLREWQRIHGRSTGGKPPETIDSNYRKIHEFLNLIPKLLVSRASYNCGEYARALSYLESYLEEGEDKSQRLLEQFTFLVEVYGSLRDPDSVEGAVQVRSYD--MSVTQDILVNRLVERQQDMITSYEQLLSSTDQMQPDHVRAMIDAYLRDTPKTAQLIADGLWQRLSDRYSDQCFAECKSELLWRLGSYDEMEELQSNWPAQCSQGCLKLRRPLTTR-IEFDSLLDGMRESVLEELR--SCSAVQQHSYANAYDAVLKLHLVHELHCSQELVEKLEQDRDEDNQEKLMKNYFDDWQYRLQIVQPQVRIQESIYSFRRNILAELQRRLTDRNHLLPHLKTELARIWLNSAQINRNAGQLQRAQLYILKAAEYQPSGLFIERAKLLWQKGDQVMAMNYLEEQLSIMRSGCQGNVKQLAAEQRHLFFRGKYLQAVYSAESMHLCADAVLKYFQEAIAVHRQSESCHVQMAQFLEKILEARQGGKSEPTGEQDDMLINVMVNYAKSLRYGSEHVYQSMPRLISLWLDT------------TESSTNTEQVKKMNDLLTNCCTALPTAVFYTVYSQMLSRLCHPVNDVFTVLRNVIIKLVEAYPQQSLWMLLPHFKSAKAHRIKRCKLVLTDSRLQNSTFQKLLQDFNSLTERLMDLTNKEVTLDR-TYKLSDLDTRLSKLCKQPEFSQILLPFEKYMQPTLPLNSDSNSSEGSHLPANQSTVNWFPYQQIYISGFQESVLILRSAAKPKKLTIRCSDGKDYDVLVKPKDDLRRDARLMEFNGLVKRYLHQDAPARQRRLHIRTYAVLPFNEECGLVEWLPNLASYRSICMNLYAQRRLVMSTRQLQSLAVPLHESIERKREVFTKQLVPAHPPVFQEWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFNCLFNQGELLPYPEVVPFRLTHNMIVAMGPLGVEGSFRKCCEITLRLLKQESKTLMSILRPFVYDVGAQTRK--------------GAATAKITKDVQRIADRLQGHVK-RQQANSIPLSTEGQVNFLINEATKVDNLASMYIGWGAFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38111-1", "uniprot_id": "ATR_YEAST", "id": "P38111-1", "name": "Serine/threonine-protein kinase MEC1", "aln": "-------------------------MESHVKYLDELILAIKDLNSGVDSKVQIKKVPTDPSS---------------------------------------------------SQEYAKSLKILNTLIRNLKDQRRNNIMKNDTIFSKTVSALALLLEYNPFLLVMKDSNGNFEIQRLIDDFLNISVLNYDNYHRIWFMRRKLGSWCKACVEFYGKPAKFQLTAHFENTMN--------------LYEQALTEVLLGKTELLKFYDTLKGLYILLYWFTSEYSTFGNS----------------IAFLDSSLGFTKFDFNFQRLIRIVLYVFDSCELAALEYAEIQLKYISLVVDYVCNRTIS------TALDAPALVCCEQLKFVLTTMHHFLDNKYGLLDNDPTMAKGILRLYSLCISNDFSKCFVDHFPIDQWADFSQSEHFPFTQLTNKALSIVYFDLKRRS-----------------------------------------------------------LPVEALKYDNKFNIWVYQSEPDSSLKNVTSPFDD----------RYKQLEKLRLLVLKKFNKTERGTLLKYRVNQLSPGFFQRAGNDFKLILNEASVSIQTCFKTNNITRLTSWTVILGRLACLESEKFSGTLPNSTKDMDNWYVCHLCDIEKTGNPFVRINPN---RPEAAGKSEIFRILHSNFLSHPNIDEFSESLLSGILFSLHRIFSHFQPPKLTDGNGQINKSFKLVQKCFMNSNRYLRLLSTRIIPLFNISDSHNSEDEHTATLIKFLQSQKLP------------------------------------------------VVKENLVIAWTQLTLTTSNDVFDTLLLKLIDIFNSDD------YSLRIMMTLQIKNMAKILKKTPYQLLSPILPVLLRQLGKNLVERKVGFQNLIELLGYSSKTILDIFQR---YIIPYAIIQYKSDVLSEIAKIMCDGDTSLINQMKVNLLKKNSRQIFAVALVKHGLFSLDILETLFLNRAPTFDKGYITAYLPDYKTLAEITKLYKNSVTKDASDSENANMILCSLRFLITNFEKDKRHGSKYKN----------------INNWTDDQEQAFQKKLQDNILGIFQVFSSDIHDVEGRTTYYEKLRVINGISFLIIYAPKKSIISALAQISICLQTGLGLKEVRYEAFRC--WHLLVRHLNDEELSTVIDSLIAFILQKWSEFN--GKLRNIVYSILDTLIKEKSDLILKLKPYTTLALVGK------PELGILARDGQFARMVNKIRSTTDLIPIFANNLKSSNKYVINQNLDDIEVYLRRKQTERSIDFTPKKVGQTSDITLVLGALLDTSHKFRNLDKDLCEKCAKCISMIGVLDVTKHEFKRTTYSENEVYDLNDSVQTIKFLIWVINDILVPAFWQSENPSKQLFVALVIQESLKYCGLSSESWDMNHKELYPNEAKLWEKFNSVSKTTIYPLLSSLYLAQSWKEYVPLKYPSNNFKEGYKIWVKRFTLDLLKTGTTEN-HPLHVFSSLIREDDGSLSNFLLPYISLDIIIKAEKGTPYADILNGIIIEFDSIFT------------------CNLEGMNNLQVDSLRMCYESIFRVFEYCKKWATEF--------------KQNYSKLHG--TFIIKDTKTTNMLLRIDEFLRTTPSDLLAQRSLETDSFERSALYLEQCYRQNPHDKNQNGQLLKNLQITYEEIGDIDSLDGVLRTFATGNLVSKIEELQYSENWKLAQDCFNVLGKFSDDPKTTTRMLKSMYDHQLYSQIISNSSFHSSDGKISLSP--DVKEWYSIGLEAANLEGNVQTLKNWVEQIESLRNIDDREVLLQYNIAKALIAISNEDPLRTQKYIHNSFRLIGTNFITSSKETTLLKKQNLLMKLHSLYDLSFLSSAKDKFEYKS-----NTTILDYRMERIGADFVPNHYILSMRKSFDQLKMN---------EQADADLGKTFFTLAQLARNNARLDIASESLMHCLERRLPQAELEFAEILWKQGENDRALKIVQEIHEKYQE--------NSSVNARDRAAVLLKFTEWLDLSNNSASEQIIKQYQDIFQIDSKWDKPYYSIGLYYSRLLERKKAEGYITNG---RFEYRAISYFLLAFEKNTAKVRENLPKVITFWLDIAAASIS--EAPGNRKEMLSKATEDICSHVEEALQHCPTYIWYFVLTQLLSRLLHSHQSSAQIIMHILLSLAVEYPSHILWYITALVNSNSSKRVLRGKHILEKYRQHSQNPHDLVSSALDLTKALTRVCLQDVKSITSRSGKSLEKDFKFDMNVAP--SAMVVPVRKNLDIISPLESNSMRG-----------YQPFR-PVVSIIRFGSSYKVFSSLKKPKQLNIIGSDGNIYGIMCK-KEDVRQDNQYMQFATTMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYS---LKSLHDRWQHTAVDGKLEFYMEQVDKFPPILYQWFLENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCLFEKGKRLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYD-------------------------RNMDHSIQKALKVLRNKIRGIDPQDGLVLSVAGQTETLIQEATSEDNLSKMYIGWLPFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. : : * . : . . ... : .: . : : :. : : . . . .: : * : . . . .: :: : . :. . . . . * .: . . : . : : .:: :. . * . ::. : : : .. . *. :. : ..: . . . . : : : : :: . : . .* . : : .: :. : * : : :: . . :. : :: . ::: * . . ::: : :. : : :: :. : * * : : : .. . * . . . : : : : .: : : . :: . .:: ..: :: . : . : .:**:: *. : . . :: : . .:: : .. : : . :: * :: : *. ::: :: *.. :. ::. : : : :: :: .: . .: : : . : . * * : : :.: . .. . : :: .:: :. :.: ..:*:. :*.:* : . : .: .* : .: :: : .:** * . .*: : :...: :. : . .. . : * : * :: *: . : . : * .: : *:* : :: . .: :: :. . .. . :. : : .: . .. . . : ** *. :: * . : *: ::*. : ..:. . : * * : : *.: *. * ::: . :: : . .. .. . . * .. : ::: . . : . : : . : : ::: :*. . :: . :. : ::*: : . :.. :: *:: *. .: : * :::. : : . :* *: **.:*: *: ::: . . : : : :: ::* ::: : :. :. : .::: * : : : ::. .. : : :*:::::*** . .: . : : .. : . :*::**: *. :. :: .:: .: **.: :* : . :* . *: * * :* . ... .:: . **. * : : * * : . * :::*... : * .: : * : * . :: * ***::.: ***: * :: * *:*:*:* : *:* :. * :* :*:* * *. *:*:.:.::**::* : : . * * . * . : : *:. . . .**:: :*: . *. * .*:.:*.:* *: ***:***:******** ****: .*. :****:***::*: : **:****** *:: .:* :*.** *::..*: : *::.: .**.::..:::* : : . *:. :: : .: ** *:.. **:***. : *. **:** .: ", "identical_positions": 184, "similar_positions": 613, "identity": "6.71%" }, { "cls_id": "homologset.agr.FB:FBgn0004368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2W0-1", "uniprot_id": "A0A0G2K2W0_RAT", "id": "A0A0G2K2W0-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "MEAEFYMTILTCLILGSLEGFQIVHVRKQQCLSINQKVIMSSCNGTSHNQQWLSTENGKFLHVKSGLCLSISNSSGGPFRPAVATPCAQAPRWTCHAQGGFLEVDNTSLFLKKQNRKVVVRKISKYLDSWMKLELNKEGRLVNESLCLKQAGLGTEVSVRITRNSAAPQIPTTSNTISYNPDHISNITETFLGSTAKTLGSTTETLRSTAETLGSTAEPYSQSSSKRDLPSLHMAGTTDTSWSPSTTPPFSSTTAETGVAEQVKCNFTVLESKVSSLSASIQWRTFGSPCNFSLIYSSDTSGPLWCHPILIDNFTYGCDPKDLQAGTIYNFRIVSLDGEERSLVLQTDPLPPARLEVNPERTTSTTLQVRWTPSSGKVTWYEVQLFDQNNQKIQEVQVQESATWSQYTFLNLTAGSSYKIGITAVSGGKRSFPVYTNGSTGPSPVEDIGISPNPNSLLISWSRGPGNVEQFRLMLMDKG--AIVQDTNVDKRDTSYAFRGLTPGHLYNVTIVTMASGLQNSRWKLGRTAPMEVSNLKVTSGGSLTSLNVKWQKPLGVIDSYSITLSHQGTVKESKTLPPRATEIQFKDLVPGRFYQVTIRCVSGELSAEKSAMG--RTVPEKVSNLVSYNEIWMKSFAVNWTPPAGDWDHYRILLFNDSLVLLNTTVGKE-ETHFALEGLELIPGRQYEVEVIVESGNLRNSERCQG--RTVPLAVLQLRIKQANETSLGITWRAPLG--EWEKYTISLMDR-----ELFVIHKSLSKDAKEYTFTNLMPGRNYKATVTSMSGDLKQSASIQGR--TVPAQVTDLEVSNQGMTSSLFTN---WTKALGDVEFYQVLLIHENVVVKNESVSSDSSWYSFR--ALRSGSLYSVVVTTVSGGIPSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAP-GEVHHYVVTLSHDS---------KVVQSLITAKFVSECSFSSLTPGRLYNVTITTKSGNYESHSFSEERTVPDKVQGISVSNSARSDYLKVSWVHATGDFDHYEVTIKNRDSFIQTKSIPKSENECVFARLVPGRLYSITVTTKS-GQYEASEQGTGRTIPEPVKNLTLLNRSTEDLHVTWSRANGDVDQYEVQLLFNDMKVFPPIYLVNTATEYQFSALTPGRHYKILVLTISGDVQQPAFIEGLTVPSTVKNIHISANGATDRLTVTWSPGGGDVDSYVVSAFRQDEK--------VESHTLPKHGSEHTFHRLEAGATYRIAIVSVSGSLRN-QIDVLGQTVPASVHGVVADNAYSSN----SLTVSWQKALGMAERYDILLLSENGVLLSNTS--EPATVKQHKFEDLTPGKKYKMQILTVSGGLFSKEVETEGRTVPAAVTNLRITENSSRHLSFSWTASEGELSWYNIFLYNPDKTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPAAVNHLKGSNRNMTDSLWFSWSPASGDFDFYELILYNPNGTKKENWREKDVTEWRFQGLIPGRKYTLYVVTHSGDLSNKVTGEGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWLPGDALTVFNPYSSKKSEGRIVNGLRPGRSYQFSVKTVSG--DSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEIEFSRKLEKEKSLLNIMMLVPHRRYLVSIKVQSAGVTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELRPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDPDRSSKSFNIKLGGEMDSLG-GKCDPSQQ------KFCDGPLKPHTAYRISIRAFTQLFDEGLKEFTKPLYSDTFFSMPITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKASHSRERSSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRSQSCDIALLPENRGKNRYNNILPYDASRVKLCNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDPLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLLRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR--------KLRNEQENPLFPIYENVNPEYHRAQQGLYERLSLTFLF-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RU80-1", "uniprot_id": "PTPRB_MOUSE", "id": "B2RU80-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRHGALTALW-------ITLSVVQTGVAEQVKCNFTLLESRVSSLSASIQWRTFASPCNFSLIYSSDTSGPMWCHPIRIDNFTYGCNPKDLQAGTVYNFRIVSLDGEESTLVLQTDPLPPARFEVNREKTASTTLQVRWTPSSGKVSWYEVQLFDHNNQKIQEVQVQESTTWSQYTFLNLTEGNSYKVAITAVSGEKRSFPVYINGSTVPSPVKDLGISPNPNSLLISWSRGSGNVEQYRLVLMDKG--AIVQDTNVDRRDTSYAFHELTPGHLYNLTIVTMASGLQNSRWKLVRTAPMEVSNLKVTNDGRLTSLNVKWQKPPGDVDSYSITLSHQGTIKESKTLAPPVTETQFKDLVPGRLYQVTISCISGELSAEKSAAG--RTVPEKVRNLVSYNEIWMKSFTVNWTPPAGDWEHYRIVLFNESLVLLNTTVGKE-ETHYALDGLELIPGRQYEIEVIVESGNLRNSERCQG--RTVPLAVLQLRVKHANETSLGITWRAPLG--EWEKYIISLMDR-----ELLVIHKSLSKDAKEFTFTDLMPGRNYKATVTSMSGDLKQSSSIKGR--TVPAQVTDLHVNNQGMTSSLFTN---WTKALGDVEFYQVLLIHENVVVKNESVSSDTSRYSFR--ALKPGSLYSVVVTTVSGGISSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAP-GEVDHYVVSLSHEG---------KVDQFLIIAKSVSECSFSSLTPGRLYNVTVTTKSGNYASHSFTEERTVPDKVQGISVSNSARSDYLKVSWVHATGDFDHYEVTIKNRESFIQTKTIPKSENECEFIELVPGRLYSVTVSTKS-GQYEASEQGTGRTIPEPVKDLTLLNRSTEDLHVTWSRANGDVDQYEVQLLFNDMKVFPHIHLVNTATEYKFTALTPGRHYKILVLTISGDVQQSAFIEGLTVPSTVKNIHISANGATDRLMVTWSPGGGDVDSYVVSAFRQDEK--------VDSQTIPKHASEHTFHRLEAGAKYRIAIVSVSGSLRN-QIDALGQTVPASVQGVVAANAYSSN----SLTVSWQKALGVAERYDILLLNENGLLLSNVS--EPATARQHKFEDLTPGKKYKMQILTVSGGLFSKESQAEGRTVPAAVTNLRITENSSRYLSFGWTASEGELSWYNIFLYNPDRTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPAAVNHLKGSHRNTTDSLWFSWSPASGDFDFYELILYNPNGTKKENWKEKDVTEWRFQGLVPGRKYTLYVVTHSGDLSNKVTGEGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWFPGDALTIFNPYSSRKSEGRIVYGLHPGRSYQFSVKTVSG--DSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEIEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPQPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDS--SSKSFNIKLGAEMDSLG-GKCDPSQQ------KFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSMPITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKASHSRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRSQSCDIALLPENRGKNRYNNILPYDASRVKLCNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDPLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAK--------KLRNEQENPLFPIYENVNPEYHR--DAIYSRH-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23467-1", "uniprot_id": "PTPRB_HUMAN", "id": "P23467-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSHGAGLALW-------ITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLD-EERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG--ILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVG--RTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKE-ETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQG--RTVPLAVLQLRVKHANETSLSIMWQTPVA--EWEKYIISLADR-----DLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGR--TVPAQVTDLHVANQGMTSSLFTN---WTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFH--SLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAP-GDVDNYEVTLSHDG---------KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKS-GQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQK--------VDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKN-QINVVGRTVPASVQGVIADNAYSSY----SLIVSWQKAAGVAERYDILLLTENGILLRNTS--EPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSG--DSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNS--NSKSFNIKLGAEMESLG-GKCDPTQQ------KFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAR--------KLRSEQENPLFPIYENVNPEYHR--DPVYSRH-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ITJ9-1", "uniprot_id": "A0A0R4ITJ9_DANRE", "id": "A0A0R4ITJ9-1", "name": "protein-tyrosine-phosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRNKAFHAAVW-------AACGILSTMVVDATECSIEIVKVISSTESIRLTLDNANVKCQYTVSVKDRHTDSKGCR---QDREHSKCQIESLDPGTWYHLDVISTL-------------------------------------------------DEKQQSQRAVTLQTR----------------------------------------PSAVENLQVSGDANSLDVSWQPGKGKTERYWIVLIDSSGRDSAWNSTVASTATSYTMKGLISGRLYNITVVTEVGELQNSASTQAQTAPASVSKLRTENNGDRNSIRVLWDKASGDVDSYLVSLTTPGSNSIEKVLPPDDTYVVFENLSPGKGYQVSVSTRSGALSNKTWITG--KADPGKVSDLVIENLSVRGALKISWTPPSGEWEHIRVALSNGSEVLRNQTVGRT-AKEILLSGLNLLPGRVYRMAVSVENGGLANTVIYEG--EIGLPPVSQLHVRHSDETSLSALWAHAASSSSRDGYIIQLFQSN---TSTVIQTRNLSRDMRECTFNVLTPGRLYDITVTTTAKIIRSSATLQGR--TQPLKVNHLKLSNKGSTDSLNAS---WEKPLGDLDFYHMLLLRDQQTVHNITASANTTSRLLP--FLRPGALHKILVTTISGSQTSKLAEAECRTVPAAVSDITVTNSGP-DFLNVSWKAAE-GDVDNYVVMLKDQE---------KIVHTLATSKATTECVFRSLVSGRLYSISIATHSGSYRNQTLLQERTKPSTVQNPTAIHSARDDFLKLYWNHASGDYDYYVVTIEHNGTRLQSQKLNRTQSDCAFSDLVPGRLYNLTVSTWS-GQHYSAVSIYGRTFPGAVGNLSLTERGGTFLRVSWTSAPGDVDHYELQILFNDTQVSAAVNLSSAIGEHLFSALTPGRLYKIVLSTHSGSYQRAEILEGRTVPSQVQSVHLSAGTADGSLRVSWSSADGDLDFYSVSLFQETHL--------QDSRRVPKHITQAEFYNLIPGQLYSVTVQSVSGSQTN-NSTTTGRTEPSTVTGLRADNELSTH----SLLVSWNPAVGVHDGYRLWLLDDGGTNIHNAS--VPAASRHHLFENLTPGRRYQAHVRTLSGTAESKDVVAEGQTRPSAVSALHVCSNTSSDLSFCWASAVGWVDGYELYLYDRDETLHYHTTLGSDALGWSFTLLQPGTHYKMTITSKSGKLSNQSSVWAHTAPASVPELHVENQGQTDSLLLSWTPAPGGLTGYSVTVDG-----REQRVGPEVTQVVFHSLVAGRLYLATVQTWSEDLSNSTTAVGRTVPAAPSSVSVS-CSGGSVDMKWHVP-DTGDYEDFEVTWFPQDTLYIS----HLRPTQRILEGLHPGRLYNISLRTVSGKRHSPVTYSRPVYHTIRTPPLPAPSIHCFPLSSTSVSCSWTPPHSDYDGFVVQCHRQGSGKAVYTHTLGNHTLSQQFDRLEPFKNYTIYVAVMSGDKQSSTVKNSVITMIDRPPVPPVTVRVNEHSAVITHFTIRFKFNCSWFSDANGAIRYFTIIATESNDVDNGLPEQRHPLPSYLDYRQNHSIKAYQTGYFHSTCAEGSDG--KVQVFEINLGAGMKHLG-GACKLDPESIQHGSHLCDGPLRSRTSYRLSVRAFTQLFDEENREFPHPLYTDTYLSLPLLTQSAPRSGLTGGITAALFLITMVLALTALLIYRKRAHKIAVQESPVMKMCKWKALPT-----SQMCLRIRSPVQAANFESHLAKLQSDSSYLLSEEFEGLKDVGRIQTQNAARLLGNRNKNRYNNILPYDSTRVRLSCLEDDPCSDYINANYIPGNNFRWEYIATQGPLPGTKDDFWRMVWEQNVHSLVMVTQCVERGMVKCDHYWPTDSEPLCYGDIVVQLLSEKVFPEWTIRDFKISCESQLRYPRMVRQFHYTIWPDHGVPDTTQSLIQFVRTVRDFINRTNSPGISVVHCSAGVGRTGTFIVLDRALQQLDRNCTVDIYGCVFDLRLHRSYMVQTECQYAYIHQCVRDVLRAR--------KLGCERDNPLFPIYNNII---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4F5-1", "uniprot_id": "Q9W4F5_DROME", "id": "Q9W4F5-1", "name": "protein-tyrosine-phosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCATRKQQQLRAHHQQQQIQIQTHG-----RKRQQLQKQRHNHHHYYQNSQQQQKHFVWLVVGILTIFLAQHANAADLVINVPNASSNANAFYRIDYSPPFG--------FPEPNTTIPASDIG---KDIKFSRALPGTEYNFWLYYTNSTHREQLTWTVNITTAPDPPANLSVQLRSSKSAFITWRPPGSGRYSGFRIRVLGLTDLPFERSYSLEGNETLQLSAKELTPGGSYQVQAYSVYQGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPFPAGIYTHYRVSITPDDAIQSVLYVEREGEPPGPAQAAFKGLVPGREYNISVQTVSEDETSSVPTTARYLTVPERVLNVTFDEAYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRRIFNVPRAANGDSVYFDYPDILEPGRTYEVVVKTIADNVNSWPASGEVTLRPRPVRSLGGFLDDRSNALHISWEPAETGRQDSYRISYHEQTNASEVPAPFPVAAESQITTNLTEYTLDSLLAGRRYLIAVQALSKGVASNASDITRYTRPAAPLIQELRSIDQGLMLSWRSDVNSRQDRYEVHYQRNGTREE-RTMATNETSLTIHYLHPGSGYEVKVHAISHGVRSEPHSYFQAVFPKPPQNLTLQTVHTNLVVLHWQAPEGSDFSEYVVRYRTDASPWQRISGLHEN-EARIKDMHYGERYLVQVNTVSFGVESPHPLELNVTMPPQPVSNVVPLVDSRNLTLEWPRPDGHVDFYTLKWWPTDEEDRVEFKNVTQLEDLSSPSVRIPIEDLSPGRQYRFEVQASSNGIRSGTTHLSTRTMPLIQSDVFIANAGHEQGQDETITLSYTPTPADSTRFDIYRFSMGDPTIKDKEKLANDTERKLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLHPLPISDLKAIQVAAREITLHWTAPAGEYTDFELQYLSADEEAPQLLQNVTKNTEITLQGLRPYHNYTFTVVVRSGSIQG----------------------------------------------------------------------------------------------------------------------------TDFADVSVSTLMRSSAPISASYQTLTAP--------PGKVDYFQPSDVQP---GEVTFEWSLEPAEQHGP--------------------------IDYFRITCQNADDAADVSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALGYGAEREHIQTMPILAPPVPEPSVTP--LEVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDVGKN----ASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGS------RKSSLEAEHFTIGTANCDKHQAG------YCNGPLRAGTTYRIKIRAFTDEDK----------FTDTVYSSPITTERSD-----TVIVAATVSAVLLVAMVLVVVYCQHRCQLIRRASKLARMQDELAALP------EGYITPNRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRN---CESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG--TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHANDGYEVTKIYLERQPQTKMGTLPIRASLAMAEKLDADLMTNKDEDEDQEQQQQQQLQLATEVKPKGSNDDEEDEEDDDDDDDDQQPLNNETTATLSSASCSSSTHDVHVVLQEAIEKPKQEQERICAGTQSHADTESDNTDSDDDDEDGDGKVAKDGAVADEDGWWY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29461-1", "uniprot_id": "PTP2_YEAST", "id": "P29461-1", "name": "Tyrosine-protein phosphatase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRIAQQYRNGKR-------------DNNGNRMASSAISEKGHIQVNQTRTPGQMPVYRGETINLSNLPQNQ---------------------------IKPCKDLDDVN----------------------------------------------------------IRRNNSNRHSKILLLDLCAGPNTNSFLGNTN-------------------AKDITVLSLPLPSTLVKR-----SNYPFENLLKNYLGSDEKYIEFTKIIKDYDIFIFS-------------------------------------------------------------------------------------------------DSFSRISSCLKTTFCLIEKFKKFICHFFP-------------------SPYLKFFLLEGSLNDS-------------KAPSLGKNKKNCILPKLDLN--LNVNLTSRS-----TLNLRINIPPPNDSNKIFLQSLKKDLIHYSPNS----------LQKFFQFNMPADLAPNDTILPNWLKFCSVKENEKVILKKLFNNFETLENFEMQRLEKCLKFKKKPLHQKQLSQKQRGPQSTDDSKLYSLTSLQRQYK----------------------------------------SSLKS------------------------------------------------------------------NIQKNQKLKLIIPKNNTSSSPSPLSS----------DDTIMSPINDYELTEGIQSFTKNRYSN---------ILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSCKPND----------YINANYLKLTQINPDFKYIA---------------------------------------------------------------------------------TQAPLPS-------------------------------------------------------------------------------------------------------------------------TMDDFWKVITLNKVKVIISLNSDDELN----------------------------------------------------------------------------LRKWDIYWNNLSYSNHTIKLQNTWENICN-------INGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLDSCGVDMNDIIKLHKVKNSLL--FNPQSFITSLEKDVCKPDLIDDNNSELHLDT-----------------------ANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIA----------CYEALLNYFALQKQIKNALPC----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. : : . .* * . : : : . . .. . : : * .* : . . .: . . ..: : : * .. .. : : . . : : . : . . . : .: .:.. : * . .:.: : * * .: * : : . . :. . : : . . : :* : . .. . * :. .. . :: :. : * . . .:*. .:. . . . :: : . . . : * : . .. *: . . :: : * .* :** . : : . ..: : . * : : * *.*. .:* :: . : * : . .* .. .: : : : :.* . : * . . : :: : :. :. .* . : :: . : * . :****** **:*.*:.** *. : . . * : . .:: .* : : . : : : ", "identical_positions": 45, "similar_positions": 193, "identity": "1.84%" }, { "cls_id": "homologset.agr.FB:FBgn0004369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BAH5-1", "uniprot_id": "A0A8M2BAH5_DANRE", "id": "A0A8M2BAH5-1", "name": "protein-tyrosine-phosphatase", "aln": "MEALATRCAFFLAQIALFS-------------------NTGLSEAYG-YRSQKKLSENVEWSYAGTLNQNNWAKKYPSCNNAKQSPINVEESLAQVKIQFQKLRLEGWLEKTSDSTTVKNDGKTVAIDVGGEFYVSGGGLRSKFKVGRISFHWGLCNASSDGSEHGLNGEKYPLEMQIYCYEADVFSDLDEAFREGGKITALAVLFETSTEDNVNYTAIIDAVNSVSRYGKSGSISPFTMQGLLPSSTEKYFIYNGSLTTPPCSETVEWIVFKNTVAISDVQLEMFCEVMTMQQVGYVMLMDYLQNNYRNQQEQFMGQVFSSYT--------------GVEEVHTPICSSEPENVQASPHNYTSMLVIWERPRAVYDSSIERYSVTYRPAQGDDESALEYLTDGDQDVGAIIQDLVANTSYMVQVVAVCTNGLYGRVSDQLTVDVPLDDPEADNDSESF-----------DYDEEENYHINPFLIRPETERLPYPFQTTTTSPRVTTTERLIHPVVKTTQRTHERRLPVEESQKTHDDIFPVVYTDKPTAKHTDQPTTITTTFVVDVHTTTPDSFR-----------------------------------------FIAGVSSESDVQSSSFTDSPTSVTPETSETLER-FVTSASIDILEVEDVTEPVTITDSFEESS------QTVAPLLE----------------------------------IPVDSTSSTFPSEVPLRP---------------------------TAASLPFPTTAAFSTVLSQTTQPVFNGES-----------------------APYAPSVSDTLSYVHASPVSP---YSLSSVLSEPIPDWDIPYTVTML----------VSGGAQSITPSPSYPTLSLSGSVSYLD-------------------------------------MESVSSGGCIDDDGDDAVLSGSASADPPCRTT-----------------LPLQTLSEVTASVDLMQPSSEPSLLHLSEHSGTISVLSTPAYLQ----------------------------PSVPVSKDYSETTTTLDTDASLSGSNGESNLLTEWVDSSLAAPTFSSK-------------------------------------------------------FSLHASSNSLLPSSVSGLPPCSSLLSSPV--------------ELHLFQSTSSASTSLCSDAGLDLSTKALLPSLSISTKPSSDLSLSVAATVNNIAQSAIGQSLGASAPIRSSAITPTPILELRS------------------------------TPTPVVPPTIA----------------------------------------------------------------PTSPSDSITVVAPVVPP-------------------TIPVSSAPESSSMPTHSADGQQENSASG----------------------------WTFDLDWGQSSASGDESIAAPYITTASPTEVSPEETDDGNEEHSSSFY---------------------------FEGENGTESEVTDFRVTLQPSPSWTLRGSGEEESGSGETLTDNETSSDFSIPERTER------------------------------ESEEEPVEDANNSSHESRVGLASSIERQKKAVVPLAVVSTLTFLGLIFLIGIYIYWR-----------------------------KCFQTAHFYIEDS-TSPRVISS--SPLLNPTGEH-EPLPVKQFVNHVTELHNTSSFSREFEILKEYFEEVQTCTVDLGTTTDCSNHPDNKNKNRYVNILAYDHSRVRLAPLNDKDGKSGGDYINANYVDGFNKNKAYIAAQGPLKSSTPDFWRMVWEQNVGVIVMITNLVEKGRKKCDQYWPLENQEEYGCFLVTVKSTNVLAYYTKRTFTLRNTSIKKGSQR---YRSNERTVTQYHYTQWPDMGVPEYVLPVLSFVYKSSKAQTDGMGPMVVHCSAGVGRTGTYIVLDSMLKQIKEKGTVNIMGFLKHIRTQRNYLVQTEEQYIFTHDALVEAILSQETEVSSSHIHQYVNNLLTPGASCKTRLEKQFKLVCQSNAKQNDCSAALSDCNRTKNRNCSLIPVEKSRVCVSSSAGET-SDYINASYVMGYRQNKEFIITQNPLPNTVKDLWRMVWDQNSQVIVSLPDRSSTTEDSEPVIFWPTRDQPIIYETFSVSLRGEDHVCLSNEDMLIVQDYILEATKDDFVLEVKHFRSPRWPNPDSPISSVFEMIRIIQKEASSKDGPMVIHDEHGGVTAGTFCALFTLLQQLEAESVVDVYMVAKMINLMRPGVFTDIDQYQFLYKAILSLVS------------------------------------------------------------TQEDEQALQSSDNNGTVPGDV-SSATESLESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58J953-1", "uniprot_id": "A0AC58J953_DANRE", "id": "A0AC58J953-1", "name": "protein-tyrosine-phosphatase", "aln": "MRPITAKPHLFIAQLWLIW-------------------HSDLAASY--LRGQRKFTEDVDWSYTGALNQKHWVKKYPVCGNARQSPIDISEEFTQVRLQYQNLQLENWEQPTTDSTTITNDGKTVVIGLNSEYFISGGGLRSRFKVGRITFHWGRCNATSDGSEHSLNGNRFPLEMQIYCFDDLEFESIDEAMSSGGKIAAVAVLFQASIEDNQDYAAIIEGVNNVSRFGKSSAVEEFSLLALLPENTEKYFMYNGSLTAPPCSENVEWIVFKNTVGISETQLEVFCEVMTMQQAGYAMLTDYLQNNYREQQQQFMGQVFSSYT--------------GTEEVPAPMCSSEPQNVQADSQNFTGIVVTWERPRAVYDTVIERYSVTYQRLQGQNPPKQQYLTDGDQDVGAIIHNLLANSSYVVQVVALCMNGLTGKMSDQVIVDMPFEDPVNEPD---------------------------------------PYGDLAES-------------------------------------------EEYNEEHTSAPS------------SKPPPGR-----------------------------------------FLIRDSG-SSISITTSTDQPGFLFPVS---------------------RTTPITVRRKITEES------SLSQPPVQ----------------------------------NKSRKNETKRPANRLLPD---------------------------DSGHFPQSN----TVVTDVYYEDVLNSST-----------------------TNITPTINNNL----------------------------------------------------------------------------------------------------------------------LIDQN------TEKASTSPPK------------------------------------QPANES-------------------------------------------------------------STANATTGSSLSAS--------------------------------------------------------------------------------------------------------------------------------------------------------MKIISQTTQPLFNDVFVTATSFNNERVLMVSDATSLYESSTRSPTIILEEGS------------------------------AHFPPS---------------------------------------------------------------------------------------------------------------------------DGQGEFSGSG----------------------------SAIFLEELDREWELEQTRMAP--KNADPRKTQ----EENHEGLPSTFF---------------------------FESEREASSTYKPQNQDFLSWVTWSAESDSGSGQGGSMISQTEDIPIQLIIPKLN---------------------------------IQEENHAEASNSSPESRVGMVGGTETEKRAVVPLAIVSTLTVLCLVVLVGILIYWR-----------------------------RCFQTAHFYVEDT-NSARAISAPSTPLLLPTEDN-EALPVKDFVKHVADLHANHKFSKEFEILKESYEEIQGCTADMGITTDSSNHPDNKSKNRYINILAYDHSRVKLSQNSDKDGKTG-DYINANYVDGFNQPKAYIAAQGPLKGSLEDFWRMIWEQNVGVIVMITNLVEKGRRKCDQYWPLENQEDYGCFLVTLKSSRTLAYYTLRTFTLRNVQIKKGSQK---GRSQERTVLHFHYTQWPDMGVPEYTLPLLSFIRTSSQARTAEMGPVVVHCSAGVGRTGTYIVIDSMLKQIKEENTVNIMGFLKHIRTQRNYLVQTEEQYVFIHDALVEAIRSKETLVSSSLIHTYVSGLLTPGPAGKTPLEKQFKLVSQSCAKQSDYTTALKESNVSKNRTACLMPVERSRVSLSAAAGES-SDYINASYLLGFHQSREFIVTQNPLPNTIHDFWRMIWDHNTQIIVSLPDTHNMSSEAE-CVYWPTKDEPISCETFTVSFRDEDSLNLSNEEPVLVQHFILEALKDDYVLEVHQFQSPRWPDPDSPISNCFELINIIREESSRREGPVLIHDGCGGSSAGLFCALVTLVNQLDEENSVDVYQTARMINLMRPGVFNDVEQYQFLYKAILSLVS------------------------------------------------------------TQEDERALQYAENNGTVP----ANPSESLESLM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B9EKR1-1", "uniprot_id": "PTPRZ_MOUSE", "id": "B9EKR1-1", "name": "Receptor-type tyrosine-protein phosphatase zeta", "aln": "MRILQS----FLACVQLLC-------------------LCRLDWAYGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPICNSPKQSPINIDEDLTQVNVNLKKLKFQGWEKASLENTFIHNTGKTVEINLTNDYYLSGGLSEKVFKASKITFHWGKCNVSSEGSEHSLEGQKFPLEMQVYCFDADRFSSFEEAVKGKGRLRALSILFEVGVEENLDYKAIIDGTESVSRFGKQAALDPFVLQNLLPNSTDKYYIYNGSLTSPPCTDTVEWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYT--------------GKEEIHEVVCSSEPENVQADPENYTSLLVTWERPRVVYDAMIEKFAVLYQPLAGNDQAKHEFLTDGYQDLGAILNNLLPNMSYVLQIVAVCSNGLYGKYSDQLIVDMPTEDAELDLFPELIGTEEIIKEEEYGKDNEEDTGLNPGRDSVTNQIRKKEPQVSTTTHYNHMGTKYNEAKTNRSPTRGSEFSGKSDVPNTSPNSTSQHVAEFETERGISLPSQTGTNLPPHNVEGTSASLNSGSKTLFIFPQMNLSGTAESLNTVPITEYKEVSADVSEEENFLTDFKLDTGADDSSGSSPSTSTVPFSSDNLSHGYITSSDMPEAITYDVLKPGSTRNAPEDSAPSGSEESLKDPSLEGSVWFPGSTDLTTQSETGSGRESFLQVNSTDIQIDESRETTESFSPDATVSQDPSVTDMGMPHYSTFAYLPTEVTPQAFTPSSRPLDLAPTINILHSQTTQPVYNGETPLQPSYSSEVFPLATPLLLDNQTLNTTPAASSSDSALHATPVSPSVGVSFESILSSYDDAPLLPFSSASFSSEMFRHLHTVSQTLPQVTSAAERDELSLHASLLVARGDLLLEPSLVQYSDVASHQATTRAASDTLGFGSESAVFYKTSMVSQIESPRSDVVMHAYSSGPEPSYTV---EGSHHVPTVSYSSAMPLHGSVDVSDQGSLLINPSHISMPESSFITPTASLLQPPPALSGDGEWSGASSDSELLLPDADGLRTLNISSPVSVAEFTYTTSVFADGIKPLSKSEMMYGNETELKMSSFSDMAYPSKSTVVPKMSDVVHKWSESLKETSVSISSMKSVFPESLVYPTTKGFEQGVSHVPEIIFPVQPTHTASQASGDTWLKPGLSANSEAAFSDTASREVVHPSTQPLLYEAATPFNTEALLQPSFQASDVDTLLKTALPSVPSDPILAGTPQVEQSSSSVSHPMASESGSSESMLHFTSVPILDISP-SKVHSTPLQGLTVPHSSKKFSEQGLLKSKSPQQVLPSLFSNDEFFQSAHLDVSQAYPPKGRHAFVTPVLSIDEPQNTLINKLVYSEDIFSSTEISITDKVLTGLPTLASDVLSSTDHSVPLGSGPISLTMVSPNRDDSVTTAKLLLPSTATSKLTQSARSDADLVGGGEDGDDYDD--DDYDDIDRGRFPVNKCMSCLPYRESREKVMNDSDTQESSLVDQSDPISPLLFENTEEENGGTGVTR-----VDKSP----PPSMLPQNHNDGKEDSDIQMGSAVLPHTPGSKAWAVLTSDEESGSGQGTSDSLNDNETSTDFSFPDVNEKDTDGVLETDDTGIAPGSPRSSTPSVTSGHSGVSNSSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWR-----------------------------KCFQTAHFYLEDN-TSPRVISTPPTPIFPISDDI-GAIPIKHFPKHVADLHASNGFTEEFETLKEFYQEVQSCTADLGITADSSNHPDNKHKNRYVNIVAYDHSRVKLTQLAEKDGKLT-DYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPTDGSEEYGSFLVNQKSVQVLAYYTVRNFTLRNTKLKKGSQK---GRSSGRLVTQYHYTQWPDMGVPEYSLPVLAFVRKAAQAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVPDSHIHSYVNTLLIPGPTGKTKLEKQFQLLSQSNILQSDYSTALKQCNREKNRTSSIIPVERSRVGISSLSGEG-TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEF--VYWPNKDEPINCESFKVTLMSEEHKCLSNEEKLIVQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISIIKEEAANRDGPMIVHDEHGGVTAGTFCALTTLMHQLEKENAMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVLSLVS------------------------------------------------------------TRQEENPSTSLDSNGAALPD--GNIAESLESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62656-1", "uniprot_id": "PTPRZ_RAT", "id": "Q62656-1", "name": "Receptor-type tyrosine-protein phosphatase zeta", "aln": "MRILQS----FLACVQLLC-------------------VCRLDWAYGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPICNSPKQSPINIDEDLTQVNVNLKKLKFQGWEKPSLENTFIHNTGKTVEINLTNDYYLSGGLSEKVFKASKMTFHWGKCNVSSEGSEHSLEGQKFPLEMQIYCFDADRFSSFEETVKGKGRLRALSILFEIGVEENLDYKAIIDGTESVSRFGKQAALDPFILQNLLPNSTDKYYIYNGSLTSPPCTDTVEWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYT--------------GKEEIHEAVCSSEPENVQADPENYTSLLITWERPRVVYDTMIEKFAVLYQPLEGNDQTKHEFLTDGYQDLGAILNNLIPNMSYVLQIVAICSNGLYGKYSDQLIVDMPTEDAELDLFPELIGTEEIIKEENYGKGNEEDTGLNPGRDSATNQIRKKEPQVSTTTHYNHMGTKYNEAKTNRSPTRGSEFSGKSDVLNTSLNPTSQQVAEFNPEREMSLPSQIGTNLPPHSVEGTSASLNSGSKTLLVFPQMNLSGTAESLNMVSITEYKEVSADLSEEENLLTDFKLDSGADDSSGSSPASSTVPFSTDNLSHGYTSSSDTPEAVTYDVLRPESTRNALEDSAPSGSEESLKDPSLEGSVWFPGSTDLTTQSETGSGREGFLQVNSTDFQVDESRETTETFSPDATASRGPSVTDMEMPHYSTFAYPPTEVTSHAFTPSSRPLDLAPTSNILHSQTTQPVYNGETPLQPSYSSEVFPLVTPLLLDNQTLNTTPAASSSDSALHATPVFPSVGVSFDSILSSYDDAPLLPFSSASFSSDLFHHLHTVSQTLPQVTSAAERDELSLHASLLVAGGDLLLEPSLVQYSDVMSHQVTIHAASDTLEFGSESAVLYKTSMVSQIESPSSDVVMHAYSSGPETSYAI---EGSHHVLTVSSSSAIPVHDSVGVADQGSLLINPSHISLPESSFITPTASLLQLPPALSGDGEWSGASSDSELLLPDTDGLRTLNMSSPVSVADFTYTTSVSGDDIKPLSKGEMMYGNETELKMSSFSDMAYPSKSTVVPKMSDIVNKWSESLKETSVSVSSINSVFTESLVYPITKVFDQEISRVPEIIFPVKPTHTASQASGDTWLKPGLSTNSEPALSDTASSEVSHPSTQPLLYEAASPFNTEALLQPSFPASDVDTLLKTALPSGPRDPVLTETPMVEQSSSSVSLPLASESASSKSTLHFTSVPVLNMSP-SDVHPTSLQRLTVPHSREEYFEQGLLKSKSPQQVLPSLHSHDEFFQTAHLDISQAYPPKGRHAFATPILSINEPQNTLINRLVYSEDIFMHPEISITDKALTGLPTTVSDVLIATDHSVPLGSGPISMTTVSPNRDDSVTTTKLLLPSKATSKPTHSARSDADLVGGGEDGDDYDD--DDYDDIDSDRFPVNKCMSCSPYRESQEKVMNDSDTQESSLVDQSDPISHLLSENTEEENGGTGVTR-----VDKSPDKSPPPSMLPQKHNDGREDRDIQMGSAVLPHTPGSKAWAVLTSDEESGSGQGTSDSLNDNETSTDFSFPDVNEKDADGVLEADDTGIAPGSPRSSTPSVTSGHSGVSNSSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWR-----------------------------KCFQTAHFYLEDN-TSPRVISTPPTPIFPISDDI-GAIPIKHFPKHVADLHASNGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYVNIVAYDHSRVKLTQLAEKDGKLT-DYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPTDGSEEYGSFLVNQKNVQVLAYYTVRNFTLRNTKIKKGSQK---GRSSGRLVTQYHYTQWPDMGVPEYSLPVLAFVRKTAQAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVPDSHIHSYVNTLLIPGPSGKTKLEKQFQLLSQSNILQSDYSTALKQCNREKNRTSSIIPVERSRVGISSLSGEG-TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEF--VYWPNKDEPINCESFKVTLMSEEHKCLSNEEKLIVQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISIIKEEAANRDGPMIVHDEHGGVTAGTFCALTTLMHQLEKENSMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVLSLVS------------------------------------------------------------TRQEENPSTSLDSNGAALPD--GNIAESLESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23471-1", "uniprot_id": "PTPRZ_HUMAN", "id": "P23471-1", "name": "Receptor-type tyrosine-protein phosphatase zeta", "aln": "MRILKR----FLACIQLLC-------------------VCRLDWANGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYT--------------GKEEIHEAVCSSEPENVQADPENYTSLLVTWERPRVVYDTMIEKFAVLYQQLDGEDQTKHEFLTDGYQDLGAILNNLLPNMSYVLQIVAICTNGLYGKYSDQLIVDMPTDNPELDLFPELIGTEEIIKEEEEGKDIEEGAIVNPGRDSATNQIRKKEPQISTTTHYNRIGTKYNEAKTNRSPTRGSEFSGKGDVPNTSLNSTSQPVTKLATEKDISLTSQTVTELPPHTVEGTSASLNDGSKTVLRSPHMNLSGTAESLNTVSITEY--------EEESLLTSFKLDTGAEDSSGSSPATSAIPFISENISQGYIFSSENPETITYDVLIPESARNASEDSTSSGSEESLKDPSMEGNVWFPSSTDITAQPDVGSGRESFLQTNYTEIRVDESEKTTKSFSAGPVMSQGPSVTDLEMPHYSTFAYFPTEVTPHAFTPSSRQQDLVSTVNVVYSQTTQPVYNGETPLQPSYSSEVFPLVTPLLLDNQILNTTPAASSSDSALHATPVFPSVDVSFESILSSYDGAPLLPFSSASFSSELFRHLHTVSQILPQVTSATESDKVPLHASLPVAGGDLLLEPSLAQYSDVLS---TTHAASETLEFGSESGVLYKTLMFSQVEPPSSDAMMHARSSGPEPSYALSDNEGSQHIFTVSYSSAIPVHDSVGVTYQGSLFSGPSHIPIPKSSLITPTASLLQPTHALSGDGEWSGASSDSEFLLPDTDGLTALNISSPVSVAEFTYTTSVFGDDNKALSKSEIIYGNETELQIPSFNEMVYPSESTVMPNMYDNVNKLNASLQETSVSISSTKGMFPGSLAHTTTKVFDHEISQVPENNFSVQPTHTVSQASGDTSLKPVLSANSEPASSDPASSEMLSPSTQLLFYETSASFSTEVLLQPSFQASDVDTLLKTVLPAVPSDPILVETPKVDKISSTMLHLIVSNSASSENMLHSTSVPVFDVSPTSHMHSASLQGLTISYASEKY-EPVLLKSESSHQVVPSLYSNDELFQTANLEINQAHPPKGRHVFATPVLSIDEPLNTLINKLIHSDEILTSTKSSVTGKVFAGIPTVASDTFVSTDHSVPIGNGHVAITAVSPHRDGSVTSTKLLFPSKATSELSHSAKSDAGLVGGGEDGDTDDDGDDDDDDRGSDGLSIHKCMSCSSYRESQEKVMNDSDTHENSLMDQNNPISYSLSENSEEDNRVTSVSSDSQTGMDRSPGKSPSANGLSQKHNDGKEENDIQTGSALLPLSPESKAWAVLTSDEESGSGQGTSDSLNENETSTDFSFADTNEKDADGILAAGDSEITPGFPQSPTSSVTSENSEVFHVSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWR-----------------------------KCFQTAHFYLEDS-TSPRVISTPPTPIFPISDDV-GAIPIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLT-DYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQK---GRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGKTKLEKQFQLLSQSNIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSGEG-TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEF--VYWPNKDEPINCESFKVTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIKEEAANRDGPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVILSLVS------------------------------------------------------------TRQEENPSTSLDSNGAALPD--GNIAESLESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05909-1", "uniprot_id": "PTPRG_MOUSE", "id": "Q05909-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGTLQESRQDSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGDEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNG-SAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTR----------------------------------------------------------------------------------------------IFQGTRIVKTGVPTAS------------------------------------------------------------PASSADMAPISSGSSTWTSSGIPFS------------------------FVSMATGMGPSS------------------------------------------------SGSQATVASVVTSTLLAG---------------------------------LGFGGGGISSFPSTVWPTR---------------------------LPTASAAS---------------------------------------------------------------------------------------------------------------------------KQAGRTVLATTEALASPGPDVH----------------------------------------------------------------------------------------------------SAPSKDSEGTEEGEK--------------------------------------------------------------------------------------------------------------------------------------------------------EEKSESEDGEREHEEE-EKDSEKKEKSEATHTAAESDRTAPAPTPSSPHRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAEGGHQTIPGRRQDHSAPATDQPG---HVAPDLDPLVDTATQVPP-------------------------------------------------TATEEHYSGSDPRRPEMPSKKPMSRGDRFSEDSK--------------------------------FITVNPAEKNTSGMLSR-----PSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDS-SSPRVVPNESVPIIPIPDDM-EAIPVKQFGKHIGELYSNSQHG-----FSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHS-DYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEEYGNIIVTLKSTKVHACYTVRRLSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPDMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETAVSSSQLHSYVNSILIPGVGGKTRLEKQFKLITQCNAKYVECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEF--VYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLIS------------------------------------------------------------TKENGNGPMTGDKNGAVLTAEESDPAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LP13-1", "uniprot_id": "F1LP13_RAT", "id": "F1LP13-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGTLQESRQGSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNG-SAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHISPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTR----------------------------------------------------------------------------------------------IFQGTRIVKTGVPTAS------------------------------------------------------------PASSADMAPISSGSSTWTSSGIPFS------------------------FVSMATGMGPSS------------------------------------------------SGSQATVASVVTSTLLAG---------------------------------LGFGGGGISSFPSTVWPTR---------------------------LPTASAAS---------------------------------------------------------------------------------------------------------------------------KQAGRPVLATTEALASPGPDGD----------------------------------------------------------------------------------------------------SAPTKDGEGAEEGEK--------------------------------------------------------------------------------------------------------------------------------------------------------EEKSESEDGEREQEEE-EKDSEKKEKSEATHTAAESDQTAPAPTPSSPHRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQEGGHQTIPGHRQDHSAPVTDQPG---HVDPGLDTLVDTATQVPP-------------------------------------------------TATEEHYSGSDPKRPEMPSKKPISRGDRFSEDSK--------------------------------FITVNPAEKNTSGMISR-----PSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDS-SSPRVVPNESIPIIPIPDDM-EAIPVKQFGKHIGELYSNSQHG-----FSGDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHS-DYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEEYGNIIVTLKSTEVHACYTVRRFSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPDMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLITQCNAKYVECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEF--VYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALARDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVS------------------------------------------------------------TKENGNGPMTGDKNGAVLTAEESDPAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23470-1", "uniprot_id": "PTPRG_HUMAN", "id": "P23470-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNG-SAGSEHSINGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKSAVRDSWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTR----------------------------------------------------------------------------------------------IFQGTRIVKTGVPTAS------------------------------------------------------------PASSADMAPISSGSSTWTSSGIPFS------------------------FVSMATGMGPSS------------------------------------------------SGSQATVASVVTSTLLAG---------------------------------LGFGGGGISSFPSTVWPTR---------------------------LPTAASAS---------------------------------------------------------------------------------------------------------------------------KQAARPVLATTEALASPGPDGD----------------------------------------------------------------------------------------------------SSPTKDGEGTEEGEK--------------------------------------------------------------------------------------------------------------------------------------------------------DEKSESEDGEREHEEDGEKDSEKKEKSGVTHAAEERNQTEPSPTPSSPNRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-EGGHQTIPGHEQDHTAVPTDQTGGRRDAGPGLDPDMVTSTQVPP-------------------------------------------------TATEEQYAGSDPKRPEMPSKKPMSRGDRFSEDSR--------------------------------FITVNPAEKNTSGMISR-----PAPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDS-SSPRVVPNESIPIIPIPDDM-EAIPVKQFVKHIGELYSNNQHG-----FSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGKDSKHS-DYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEF--VYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAMLSLVS------------------------------------------------------------TKENGNGPMTVDKNGAVLIADESDPAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQH6-1", "uniprot_id": "A0A8M1QQH6_DANRE", "id": "A0A8M1QQH6-1", "name": "protein-tyrosine-phosphatase", "aln": "MWRLRGPCRLGMLCLTLSALLIQPISCHPAS------HVETVRRGSSANQRERRASGEPYWAYSGTYGPRRWASAYPECGERNQSPVDILDPETQVSQECQELTLDGFETKSSNRTTMKNTGKTVSIVLKNDYFVRGAGLPGRFKAEKVEFHWGSTNG-SAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERRIIAAMAVFFQVATKDNIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLGSYYRYTGSLTTPPCSKVVEWIIFSRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIFKSALMDAW---MPETMASAADTETSRVCSSIPDNMKLHPLNRTALVLTWDRPSAVYHPPIVGFLVSYSWVKDEMPFEKTFTQSSEHSTRAVITLVSPDVLYLFRVQALCQRDQRSDFSQTLLFKANTTR----------------------------------------------------------------------------------------------IFEGTRIVKTGMPTVS------------------------------------------------------------PASSADMAPISSGSSTWTSAGLPFS------------------------FVSMATGMGPPS------------------------------------------------SGGQATVASVVTSTLLAG---------------------------------LGFSGSVISSLPGSFWPTH---------------------------STNTGPSP---------------------------------------------------------------------------------------------------------------------------TQHP----ATPTAENSPSED---------------------------------------------------------------------------------------------------------STDTQNKLEEEE--------------------------------------------------------------------------------------------------------------------------------------------------------EHKKEDDEEEEEEEEEEEQRDEEKKKKGKDVTVKDKKQTVQKPTAPIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSKHRDRERPDAESST---LTPAEVEEQVSGATERPD-------------------------------------------------AEDSSKATWQDDNDMQIPSSSTESSKLSDEEKAN--------------------------------WPYYINTERNSISTVSRD--SVSSSSRMEWIIPLMVVSALTLLCLIMLLAVLVYWR-----------------------------RFFQTAHFYIEDR-NSPRVIHNDSFPIISTADDL-EAMPVRQFIKHIMELHSNNRHG-----FSQEFDEVQHCTSEMKITAEHSNHPENKHKNRYINIVAYDHSRVKLQQLPGKDSKHS-DYINANYVDGYKRARAYIAAQGPLKSTFEDFWRMIWEQNTTVIVMITNLVEKGRRKCDQYWPSENSEVYGNIMVTLKSTKVYAYYTLRHFIVRNSKLKKGQKG----RQNERLVLQYHYTQWPDMGVPEYTLPVLKFISRSTVTHASSTGPVLVHCSAGVGRTGTYIVIDSMLKQIKDRGSVNVLGFLKHIREQRNYLVQTEEQFIFIHDALMEAVLSKDTEVSAWQLHTYTNSLLTPSPTGHTRMDKHFKLLTQCNAHLAECLSGQKECNKEKNRTSAVLPTERARVALSPLPGLKGTDYINASYIMGYYRSNEFIITQHPLPHTTTDFWRMIWDHNAQVIVMLPDNLGLTEDEF--VYWPSREEPMNCIAFTVTLINTDRLCLSNEEQLIIHDFILEATQDDYVLEVRHFQCPNWPDPDASISSTFELINIIKEEAMTRDGPTIVHDEFGAVSAGTFCALTTLSQQLENESAVDVYQVAKMINLMRPGVFTEIEHYHYLYQAMLSLVS------------------------------------------------------------SKDFRFGFNYMDKFAG--KADESNQAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35832-1", "uniprot_id": "PTP99_DROME", "id": "P35832-1", "name": "Tyrosine-protein phosphatase 99A", "aln": "--------------------------------------------------------------------------------------MPRPQHHALLRAMLKLLLFASIAEHCATALPTNSSN-------------------------------------SPSSPSPFTAASLPPTTASSSSSPAVIS---------------------TSSSDRNLADLVNPEAETTGSGWESLETEFNLATTVDSSTQKTEKE------PVLGTVATSIEQQDQPPDVPATTLAFANAFPVPVAGEMGNGNGNYNDATP----------------------------PYAAVDDNYVPSKPQNLTILDVSANSITMSWHPPKNQNGAIAGYHVFHIHDNQTGVEIVKNSRNSVETLIHFELQNLRPYTDYRVIVKAFTTKN-EGEPSDQIAQRTDVGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSAPAIVNLTCHSQESITIRWRRP----------------------------------------------------------------------------------YEFYNTIDFYIIKTRLAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDTHRDIR---------------------------------------------------------------------------------------------------------------------------------------------------------------INASAKELETAMILQNLTTNSYYEVKVAAATFSVINPKKIVLGKFSE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRIIQLQPNCEKLQPLLR------------------------------------------------------------------------------------------------------------------------------------------------------------QSHNDYNLAVLVGIIFSCFGIILIIMAFFLWSR----------------------------KCFHAAYYYLDDPPHHPNAPQVDWEVPVKIGDEIRAAVPVNEFAKHVASLHADGDIG-----FSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQ--KKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCN-----TEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAIASGETNLMAEQVEELKN--------CTPYLEQQYKNIIQFQPKDIHIASAMKQVNSIKNR-GAIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDINFAQF----WPDEATPIESDHYRVKFLN-----KTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIVDVHERCNDYRNGPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNILSFLPGNLNLLKRTALRTEFEDVTTATPDLYSKICSNGNVPQHVILQQQQLHMLQLQQQHLETQQQQQQQQQQQQQQQQQTALNETVSTPSTDTNPSLLPILSLLPPTVAPLSSSSSTTPPPPSTPTPQPPQTIQLSSHSPSDLSHQISSTVANAGSPATASAGATPTTPMTPTVPPTIPTIPSLASQNSLTLTNANFHTVTNNAADLMEHQQQQMLALMQQQTQLQQQYNTHPQQHHNNVGDLLMNNADNSPTASPTITNNNHITNNNVTSAAATDAQNLDIVG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTSSPVLLKRATAPVLP--------------SFKPKEQRYNKPQGCSLITAVELGKIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPSTLLR---RKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTAN--QTESSVSLPCYGIASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPKS-----------------------PKTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPD---DSRSDHSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAPQTNINQMFKFSQNEEIMGLETYLSAVNIKEEH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERWYNNDSAKKSLQNFQFP---------------------------------------------------------------------------------------KNQNSLEKDTNKDK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QFQKLDFLEKRRLN------------------------------------------------------------------------------------------------------------------------------------------------------------HSVSFRKKENSFILEKPSSYPEQLTSTSSSTIMP-----------------------------PKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESDSDSESDDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTS-DGGILDNYINANYLSLPRFSVEQNSSFQTTTT-----------TTRRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYWQEGNYNGIHVKLLEKKILKMPSTTSMRKNTMGTQNSSLYSAG-----------VQGNSSNYSTDNDNDNDN-------NNNNNNNSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKP-------YELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDT--------------------------LFARNYYQNDQLPTILVHCSAGCGRTGTLCTIDS----------------ILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQRISMVQN----------------------------------------------INQFIFIYDCLLFYFRLRLDDITERTD--------------------------------GDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . * . .: :: . : : . . * * : . : : * . : : * . . . : . . . . : . : .. : : : * . . . . . . . : . .* : . . * :. :.*:* . .*. : . : :*.:*.*: .: *: : :: . ::: :** .*.* .** ** . : : . : : * : . . . : : :::. . : . . . *. . . . *:: :* :.. : * : .: :: ::::*: : : . : . : . . .* : . : * :.: .:*: : * * : :: : : ..::: : : :: . .: * :: :* ::: . :.: :: . : ", "identical_positions": 36, "similar_positions": 173, "identity": "1.36%" }, { "cls_id": "homologset.agr.FB:FBgn0004370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2W0-1", "uniprot_id": "A0A0G2K2W0_RAT", "id": "A0A0G2K2W0-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "MEAEFYMTILTCLILGSLEGFQIVHVRKQQCLSINQKVIMSSCNGTSHNQQWLSTENGKFLHVKSGLCLSISNSSGGPFRPAVATPCAQAPRWTCHAQGGFLEVDNTSLFLKKQNRKVVVRKISKYLDSWMKLELNKEGRLVNESLCLKQAGLGTEVSVRITRNSAAPQIPTTSNTISYNPDHISNITETFLGSTAKTLGSTTETLRSTAETLGSTAEPYSQSSSKRDLPSLHMAGTTDTSWSPSTTPPFSSTTAETGVAEQVKCNFTVLESKVSSLSASIQWR-TFGSPCNFSLIYSSDTSGPLWCHPILIDNFTYGCDPKDLQAGTIYNFRIVSLDGEERSLVLQTDPLPPARLEVNPERTTSTTLQVRWTPSSGKVTWYEVQLFDQNNQKIQEVQVQESATWSQYTFLNLTAGSSYKIGITAVSGGKRSFPVYTNGSTGPSPVEDIGISPNPNSLLISWSRGPGNVEQFRLMLMDKG--AIVQDTNVDKRD--TSYAFRGLTPGHLYNVTIVTMASGLQNSRWKLGRTAPMEVSN-LKVTSGGSLTSLNVKWQK--PLGVIDSYSITLSHQGTVK-----ESKTLPPRATEIQFKDLVPGRFYQVTIRCVSG-ELSAEKSAMGRTVPEKVSNLVSY-NEIWMKSFAVNWTPPAGDWDHYRILLFNDSLVLLNTTVGKEETHFALEGLELIP-GRQYEVEVIVESGNLRNS-ERCQGRTVPLAVLQLRIKQANETSLGITWRAPLG--EWEKYTISLMDR--ELFVIHKSLSKDAKEYTFTNLMPGRNYKATVTSMSGDLKQSAS---IQGRTVPAQVTDLEVSNQGMTSSLFTNWTKALGDVEFYQVLLIHENVVVKNESVSSDSSWYSFRALRSGSLYSVVVTTVSGGIPSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAPGEVHHYVVTLSHDSKVVQSLITAKFVSECSFSSLTPGRLYNVTITTKSGNYESHSFSEERTVPDKVQGISVSNSARSDYLKVSWVHATGDFDHYEVTIKNRDSFIQTKSIPKSENE---------CVFARLVPGRLYSITVTTKS-GQYEASEQGTGRTIPEPVKNLTLLN----RSTEDLHVTWSRANGDVDQYEVQLLFN-DMKVFPPIYLVNTAT-EYQFSALTPGRHYKILVLTISGDVQQPAFIEGLTVPSTVKNIHISANGATDRLTVTWSPGGGDVDSYVVSAFRQDEKVESHTLPKHGSEHTFHRLEAGATYRIAIVS-------VSGSLRNQIDVLGQTVPASVHGVVADNAYSS---NSLTVSWQKALGMAERYDILLLSENGVLLSNTSEPATVKQH-KFEDLTPGKKYKMQILTVSGGLFSKE--------VETEGRTVPAAVTNLRITENSSRHLSFS---WTASEGELSWYNIFLYNPDKTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPAAVNHLKGSNRNMTDS--LWFSWSPASGDFDFYELILYNPNGTKKENWREKDVTEWRFQGLIPGRKYTLYVVTHSGDLSNKVTGEGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDY----NDFELQWLPGDALTVFNPYSSKKSEGRIVNGLRPGRSYQFSVKTVSG--DSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEIEFSRKLEKEKS-------LLNIMMLVPHRRYLVSIKVQSAGVTSEVVEDSTITMIDRPPPP-PPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELRPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDPDRSSKSFNIKLGGEMDSLGGKCDPSQQ------KFCDGPLKPHTAYRISIRAFTQLFDEGLKEFTKPLYSDTFFSMP-ITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKASHSRERSSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRSQSCDIALLPENRGKNRYNNILPYDASRVKLCNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDPLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLLRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYG---AVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRNEQENPLFPIYENVNPEYHRAQQGLYERLSLTFLF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RU80-1", "uniprot_id": "PTPRB_MOUSE", "id": "B2RU80-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRHGALTALW-------ITLSVVQTGVAEQVKCNFTLLESRVSSLSASIQWR-TFASPCNFSLIYSSDTSGPMWCHPIRIDNFTYGCNPKDLQAGTVYNFRIVSLDGEESTLVLQTDPLPPARFEVNREKTASTTLQVRWTPSSGKVSWYEVQLFDHNNQKIQEVQVQESTTWSQYTFLNLTEGNSYKVAITAVSGEKRSFPVYINGSTVPSPVKDLGISPNPNSLLISWSRGSGNVEQYRLVLMDKG--AIVQDTNVDRRD--TSYAFHELTPGHLYNLTIVTMASGLQNSRWKLVRTAPMEVSN-LKVTNDGRLTSLNVKWQK--PPGDVDSYSITLSHQGTIK-----ESKTLAPPVTETQFKDLVPGRLYQVTISCISG-ELSAEKSAAGRTVPEKVRNLVSY-NEIWMKSFTVNWTPPAGDWEHYRIVLFNESLVLLNTTVGKEETHYALDGLELIP-GRQYEIEVIVESGNLRNS-ERCQGRTVPLAVLQLRVKHANETSLGITWRAPLG--EWEKYIISLMDR--ELLVIHKSLSKDAKEFTFTDLMPGRNYKATVTSMSGDLKQSSS---IKGRTVPAQVTDLHVNNQGMTSSLFTNWTKALGDVEFYQVLLIHENVVVKNESVSSDTSRYSFRALKPGSLYSVVVTTVSGGISSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAPGEVDHYVVSLSHEGKVDQFLIIAKSVSECSFSSLTPGRLYNVTVTTKSGNYASHSFTEERTVPDKVQGISVSNSARSDYLKVSWVHATGDFDHYEVTIKNRESFIQTKTIPKSENE---------CEFIELVPGRLYSVTVSTKS-GQYEASEQGTGRTIPEPVKDLTLLN----RSTEDLHVTWSRANGDVDQYEVQLLFN-DMKVFPHIHLVNTAT-EYKFTALTPGRHYKILVLTISGDVQQSAFIEGLTVPSTVKNIHISANGATDRLMVTWSPGGGDVDSYVVSAFRQDEKVDSQTIPKHASEHTFHRLEAGAKYRIAIVS-------VSGSLRNQIDALGQTVPASVQGVVAANAYSS---NSLTVSWQKALGVAERYDILLLNENGLLLSNVSEPATARQH-KFEDLTPGKKYKMQILTVSGGLFSKE--------SQAEGRTVPAAVTNLRITENSSRYLSFG---WTASEGELSWYNIFLYNPDRTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPAAVNHLKGSHRNTTDS--LWFSWSPASGDFDFYELILYNPNGTKKENWKEKDVTEWRFQGLVPGRKYTLYVVTHSGDLSNKVTGEGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDY----NDFELQWFPGDALTIFNPYSSRKSEGRIVYGLHPGRSYQFSVKTVSG--DSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEIEFSRKLEKEKS-------LLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPQP-PPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDS--SSKSFNIKLGAEMDSLGGKCDPSQQ------KFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSMP-ITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKASHSRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRSQSCDIALLPENRGKNRYNNILPYDASRVKLCNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDPLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYG---AVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAKKLRNEQENPLFPIYENVNPEYHR--DAIYSRH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23467-1", "uniprot_id": "PTPRB_HUMAN", "id": "P23467-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSHGAGLALW-------ITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWR-ILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLD-EERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG--ILVHGGVVDKHA--TSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSN-LKVTNDGSLTSLKVKWQR--PPGNVDSYNITLSHKGTIK-----ESRVLAPWITETHFKELVPGRLYQVTVSCVSG-ELSAQKMAVGRTFPDKVANLEAN-NNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVP-GRQYEVEVIVESGNLKNS-ERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVA--EWEKYIISLADR--DLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSS---VKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENE---------CVFVQLVPGRLYSVTVTTKS-GQYEANEQGNGRTIPEPVKDLTLRN----RSTEDLHVTWSGANGDVDQYEIQLLFN-DMKVFPPFHLVNTAT-EYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIAS-------VSGSLKNQINVVGRTVPASVQGVIADNAYSS---YSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQH-KFEDLTPGKKYKIQILTVSGGLFSKE--------AQTEGRTVPAAVTDLRITENSTRHLSFR---WTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDS--LWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDY----NDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSG--DSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKS-------LLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPP-PPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNS--NSKSFNIKLGAEMESLGGKCDPTQQ------KFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLP-ITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYG---AVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHR--DPVYSRH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ITJ9-1", "uniprot_id": "A0A0R4ITJ9_DANRE", "id": "A0A0R4ITJ9-1", "name": "protein-tyrosine-phosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRNKAFHAAVW-------AACGILSTMVVDATECSIEIVKVISSTESIRLTLD-NANVKCQYTVSVKDRHTDSKGCR---QDREHSKCQIESLDPGTWYHLDVISTLDEKQ------------------QSQRAVTLQTR-----------------------------------------------------------------------PSAVENLQVSGDANSLDVSWQPGKGKTERYWIVLIDSSGRDSAWNSTVASTA--TSYTMKGLISGRLYNITVVTEVGELQNSASTQAQTAPASVSK-LRTENNGDRNSIRVLWDK--ASGDVDSYLVSLTTPGSNS-----IEKVLPPDDTYVVFENLSPGKGYQVSVSTRSG-ALSNKTWITGKADPGKVSDLVIE-NLSVRGALKISWTPPSGEWEHIRVALSNGSEVLRNQTVGRTAKEILLSGLNLLP-GRVYRMAVSVENGGLANT-VIYEGEIGLPPVSQLHVRHSDETSLSALWAHAASSSSRDGYIIQLFQSNTSTVIQTRNLSRDMRECTFNVLTPGRLYDITVTTTAKIIRSSAT---LQGRTQPLKVNHLKLSNKGSTDSLNASWEKPLGDLDFYHMLLLRDQQTVHNITASANTTSRLLPFLRPGALHKILVTTISGSQTSKLAEAECRTVPAAVSDITVTNSGP-DFLNVSWKAAEGDVDNYVVMLKDQEKIVHTLATSKATTECVFRSLVSGRLYSISIATHSGSYRNQTLLQERTKPSTVQNPTAIHSARDDFLKLYWNHASGDYDYYVVTIEHNGTRLQSQKLNRTQSD---------CAFSDLVPGRLYNLTVSTWS-GQHYSAVSIYGRTFPGAVGNLSLTE----RGGTFLRVSWTSAPGDVDHYELQILFN-DTQVSAAVNLSSAIG-EHLFSALTPGRLYKIVLSTHSGSYQRAEILEGRTVPSQVQSVHLSAGTADGSLRVSWSSADGDLDFYSVSLFQETHLQDSRRVPKHITQAEFYNLIPGQLYSVTVQS-------VSGSQTNNSTTTGRTEPSTVTGLRADNELST---HSLLVSWNPAVGVHDGYRLWLLDDGGTNIHNASVPAASRHH-LFENLTPGRRYQAHVRTLSGTAESKD--------VVAEGQTRPSAVSALHVCSNTSSDLSFC---WASAVGWVDGYELYLYDRDETLHYHTTLGSDALGWSFTLLQPGTHYKMTITSKSGKLSNQSSVWAHTAPASVPELHVENQGQTDS--LLLSWTPAPGGLTGYSVTVDG-----REQRVGPEVTQVVFHSLVAGRLYLATVQTWSEDLSNSTTAVGRTVPAAPSSVSVS-CSGGSVDMKWHVP-DTGDY----EDFEVTWFPQDTLYIS----HLRPTQRILEGLHPGRLYNISLRTVSGKRHSPVTYSRPVYHTIRTPPLPAPSIHCFPLSSTSVSCSWTPPHSDYDGFVVQCHRQGSGKAVYTHTLGNHTL-------SQQFDRLEPFKNYTIYVAVMSGDKQSSTVKNSVITMIDRPPVP-PVTVRVNEHSAVITHFTIRFKFNCSWFSDANGAIRYFTIIATESNDVDNGLPEQRHPLPSYLDYRQNHSIKAYQTGYFHSTCAEGSDG--KVQVFEINLGAGMKHLGGACKLDPESIQHGSHLCDGPLRSRTSYRLSVRAFTQLFDEENREFPHPLYTDTYLSLP-LLTQSAPRSGLTGGITAALFLITMVLALTALLIYRKRAHKIAVQESPVMKMCKWKALPT-----SQMCLRIRSPVQAANFESHLAKLQSDSSYLLSEEFEGLKDVGRIQTQNAARLLGNRNKNRYNNILPYDSTRVRLSCLEDDPCSDYINANYIPGNNFRWEYIATQGPLPGTKDDFWRMVWEQNVHSLVMVTQCVERGMVKCDHYWPTDSEPLCYGDIVVQLLSEKVFPEWTIRDFKISCESQLRYPRMVRQFHYTIWPDHGVPDTTQSLIQFVRTVRDFINRTNSPGISVVHCSAGVGRTGTFIVLDRALQQLDRNCTVDIYG---CVFDLRLHRSYMVQTECQYAYIHQCVRDVLRARKLGCERDNPLFPIYNNII---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35992-5", "uniprot_id": "PTP10_DROME", "id": "P35992-5", "name": "Tyrosine-protein phosphatase 10D", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYQLSKATTRIRLKRQ-----KAVPQHRWLWSLAFLAAFTLKDVRCADLAISIPNNPGLDDGASYRLDYSPPFGYPEPNTTIASREIGDEIQFSRALPGTKYNFWLYYTNFTHHD-------------WLTWTVTITTAPD-------------------------------------------------------------------------PPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLGLSEASSSYNRTFQVNDNTFQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPYPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSEDEISLPTTAQYRTVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRRQSTVPRSNEPVAFFDFRDIAEPGKTFNVIVKTVSGKVTSWPATGDVTLRPLPVRNLRSINDDKTNTMIITWEADPASTQDEYRIVYHEL-ETFNGDTSTLTTDRTRFTLESLLPGRNYSLSVQAVSKKMESNETSIFVVTRPSSPIIEDLKSIRMG----LNISWKSDVNSKQEQYEVLYSRNGTSDLRTQKTKESRLVIKNLQPGAGYELKVFAVSHDLRSEPHAYFQAVYPNPPRNMTIETVRSNSVLVHWSPPESGEFTEYSIRYRTDSEQQWVRLPSVRSTEADITDMTKGEKYTIQVNTVSFGVESPVPQEVNTTVPPNPVSNIIQLVDSRNITLEWPKPEGRVESYILKWWPSDNPGRVQTKNVSENKSADDLSTVRVLIGELMPGVQYKFDIQTTSYGILSGITSLYPRTMPLIQSDVVVANGEKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQSYSVWLPYQAIDPYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTFADLPCNRPKNRFTN-ILPYDHSRFKLQPVDD--DEGSDYINANYVPGHNSPREFIVTQG-PLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVGPAREMHDNEGYEGQQVQLDE---------NGDVVATIEGHLSHHDLQQAEAEAIDDENAAILHDDQQPLTSSFTGHHTHMPPTTSMSSFGGGGGGHTNVDAPDRXHSVVNQSDNNNSVVIVLVDNKPSSMICKDSKGGNIDVLESQQQQQQQQQQQPNQGGHNITTISAINGYNTLQHRRKSQLITFSSS--SCDIKNSLSHEYINGSNGSAANGPPSSGSGSGSGPGSNR---ASRANVRLSFAEEDVMILPQNHSQQSNHQDDEVFTRRRSLLEVEIGVEVG--EDGELAPHEMEEDLEEED--EDEELYMHDEFETHIDTKSNNANDDSGGGSYEDSHALHSSLGGSNRNSLEKDDDDIEVDVISTDVSCYDQLLGSSCNTRNGDDDDIATLVGDGDYSTTKLSKASRLSGAGVGGLVVSGGGGGTAIGGGIAVNGGGVLGNGVGSEAGGGIIYANPFMDDEGIAESGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29461-1", "uniprot_id": "PTP2_YEAST", "id": "P29461-1", "name": "Tyrosine-protein phosphatase 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRIAQQYRNGKRDNNGNRMASSAISEKGHIQVNQTRTPGQMPVYRGETINLSNLPQNQIKPCKDLDDVNIRRNNSNRHSKILLLDLCAGPN-------------------------TNSFLGNTNAKDITVLSLPLPSTLVKRSNYPFENLLKNYLGSD--------EKYIEFTKIIKDYDIFIFSDSFS-RISSCLKTTFCLIEKFKKFICHFFPSPYLKFFLLEGSLNDSKAPSLGKNKKNCILPKLDLN--------------------------------LNVNLTSRSTLNLRINIPPPNDSNKIFLQS----------LKKDLIHYSPNSLQKFFQFNMPADLAPN---DTILPNWLKFCSVKENEKVILKK-------------------LFNNFETLENFEMQRLEKCLKFKKKP----------------------LHQKQLSQKQRGPQ------------------STDDSKLYSLTSLQRQYKSSLKSNIQKNQKLKLIIPKNNTSSSPSPLSSDDTIMSPINDYELTEGIQSFT------------------------------------------------------KNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKN---------------------------------HSCKPNDYINANYLKLTQ-----------------INPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYWNNLSY----------------------------------------------------------------SNHTIKLQNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLDSCG------------VDMNDIIKLHKVKNS------------LLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSP-----------LLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSN--------------------------------KIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYFALQKQIKNALPC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . .. : : : : :. . : . . * : . * . .: : : : :: . . : . . : : : : *. :: : * . . . .: . : : * . .: . . : .. .: : :::: . . : : . : * . : . .. . . . : . : . . . . . . . : . * . . : * * ** .. : . . . . * . : : : . . . : :: : : : * . . :: : . . : : : . . . : : : : . :* *. ", "identical_positions": 15, "similar_positions": 131, "identity": "0.64%" }, { "cls_id": "homologset.agr.FB:FBgn0004372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R885-1", "uniprot_id": "M0R885_RAT", "id": "M0R885-1", "name": "", "aln": "MHRGGQPLKKRRGSFKMAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNAGPAVEMPFRNSKRSRLFS--------DEDDRQINTKSPKRNQRVAMIPQKFTATMSTPDKKASQK-----------IGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVA---DVSQFKDLPDEIPLPLVIGTKVTARLRG-IHDGLFTGQIDAVDTLNATYRVTFDRT-GLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRF--FMTPPRLHYTPPLQSPITDGDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTKLSKILMIKKEHIKKLREMNTEAEKLKSYSMPIGIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQ---PTDMRRRCEEEAQEIVRQANS-ASGQPCVENENLTDLISRLTAILLQIKCLAE--GGDLNSFEFKSLTDSLNDIKNTID--------------ASNISCFQNN--VEIHVAHIQSGLSQMGNLHAFAANNTNRD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C735-1", "uniprot_id": "LIN9_MOUSE", "id": "Q8C735-1", "name": "Protein lin-9 homolog", "aln": "----------------MAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNAGPAVEMPFRNSKRSRLFS--------DEDDRQINTKSPKRNQRVAMIPQKFTATMSTPDKKASQK-----------IGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVA---DVSQFKDLPDEIPLPLVIGTKVTARLRG-IHDGLFTGQIDAVDTLNATYRVTFDRT-GLGTHTIPDYEVLSNEPHETMPISAFGQKQRPSRF--FMTPPRLHYTPPLQSPITDGDPLLGQSPWRSKVSGSDTETLGGFPVEFLIQVTKLSKILMIKKEHIKKLREMNTEAEKLKSYSMPIGIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQ---PTDMRRRCEEEAQEIVRQANS-ASGQPCVENENLTDLISRLTAILLQIKCLAE--GGDLNSFEFKSLTDSLNDIKNTID--------------ASNISCFQNN--VEIHVAHIQSGLSQMGNLHAFAANNTNRD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TKA1-1", "uniprot_id": "LIN9_HUMAN", "id": "Q5TKA1-1", "name": "Protein lin-9 homolog", "aln": "----------------MAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNTSSAVEMPFRNSKRSRLFS--------DEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQK-----------IGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVA---DVSQFKDLPDEIPLPLVIGTKVTARLRG-VHDGLFTGQIDAVDTLNATYRVTFDRT-GLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRF--FMTPPRLHYTPPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQ---PTDMRRRCEEEAQEIVRHANS-STGQPCVENENLTDLISRLTAILLQIKCLAE--GGDLNSFEFKSLTDSLNDIKSTID--------------ASNISCFQNN--VEIHVAHIQSGLSQMGNLHAFAANNTNRD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHQ8-1", "uniprot_id": "LIN9_DANRE", "id": "Q5RHQ8-1", "name": "Protein lin-9 homolog", "aln": "----------------MAELEQLLDESSSAKALVSLREGSLSNTLNEK-NNLPKSQTTRGRSSYVSMETPTRSSKRSRLSC--------EDEERPIASRSPRRSQRVTTMPQKLTN-VATPDKRVSQK-----------IGLRLRNLLKLPKAHKWCIYEWFYSNIDRPLFEGDNDFCLCLKESFPNLKTRKLTRVEWGTIRRLMGKPRRCSSAFFAEERMALKQKRQKMRLLQQRKIT---DMSLCKDLPDEIPLPLVIGTKVTARLRG-VHDGLFTGQIDAVDTSAATYRVTFDRN-GLGTHTVPDYEVLSNEPHETMPISAFAQKQRPPRFQNFLTPPRGSYTGSTQSILMDNDPLFSQSPWRSKLTGTDGETLGGFPVKFLVQVTRLSKILMIKKEHIKHLKEMNTEAEKLKSYSMPIGLDLQKRYATTVLDLEQLNKDLNKVLHEVQQFCFELAPDQGMQPADQ---PSELRRRCEEESQDVLRQNNTLASGEPRVQNTELTQLISRLTALLLQIRCLAE--GGDLNSFEFKSLTDSLNDIKSSID--------------DSNLSCFQDN--VEIHVAHIQSGLSQLGNLHAFSANNTNRT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZW3-1", "uniprot_id": "Q9VZW3_DROME", "id": "Q9VZW3-1", "name": "", "aln": "-----------------MSVDPLSIDNFTIQSEICEENEFLANIGLLSTTTMSRHQLKKPRKMVAAWQNDELFIKRPNFAPRIRISEKPEIQGRIKPGVASKRTENFTKKPSNISVDVSEDEKAKEKEKEQDPYSNDFILGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFMPRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNPKENVGYLDQIPKRVPLPLAKDATVSSFLHGNSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVLSLPDSQLYSDEETAAVPLSIIMRGNKSSSVISESAKTEKFGNKRYTKELLESVLRVG--------------KLQDVKHKILMDLARMN-------EDFETFKEIGSSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEPLRILHDYLVEYQKQDEEEESKRGRPASEVYQKCRMQAEQDLKTAAD--EKFLKIESDRTQEFVRNLHTILYLNGKLGRENSSNLETIIADLVTHMVDNIQPSLGRKLKDGVDSLEPLRQQVVQIFKDVKKPERFQITQQAPMQTEDGIYNFVVEAQPDTPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: * :. : :: :. .: *:* . ..: : : *. : : **..: : : * :.:*.:..: *.::: :: :* .:: :* ** *:** .:*:* *:. * :*:* : . *: : * * *:: :.* * :** ***.** *:**: ** *: :*: :* ***:*. ::. .::*..:****. .:.*:: *:* .:*:..* : . *. ** * *:*. . . ::** :: *:* ::*:: : : ::.. . : .. . . : :. .. .* .. ::*::::::. *.:: ::*:.:.:.: .: * ::*:**:: :: *.::* *: : *: :::: * :: : :.: .::: ::*. :::: :: ::. . ::: .* ::* *.. ..:*::: . :*. :::*: ::. . :. *:: * . *: :. ..:: * .: ", "identical_positions": 92, "similar_positions": 231, "identity": "15.13%" }, { "cls_id": "homologset.agr.FB:FBgn0004373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08561-1", "uniprot_id": "PI4KB_RAT", "id": "O08561-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMVVEP------------------------ATLKPTSEPTPS----------PSGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAISSKGSPL---------------------------------------ELVNGDGVDNEIRCLDDP-------------------------PTEIREEEDEMEPGVVSGTAKGTRRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPTLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTNVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKC8-1", "uniprot_id": "PI4KB_MOUSE", "id": "Q8BKC8-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMVVEP------------------------ATLKPTSEPTPS----------PSGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAISSKGTPL---------------------------------------ELVNGDGVDNEIRCLDDP-------------------------PAQIREEEDEMGAGVASGTAKGARRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFYFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPTLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTSVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBF8-1", "uniprot_id": "PI4KB_HUMAN", "id": "Q9UBF8-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDTVVEP------------------------APLKPTSEPTSG----------PPGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAVSSRGTPL---------------------------------------ELVNGDGVDSEIRCLDDP-------------------------PAQIREEEDEMGAAVASGTAKGARRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPSLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTSVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q49GP3-1", "uniprot_id": "PI4KB_DANRE", "id": "Q49GP3-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDTELELSP-------THLEELQKSPSTSTTSSLSLPSSPSSG----------PHPLTSSSPSTSEG-------LPTSSPPLDVISEGLGELSLVIDTEV-AKKACQEVLQKVKFLKGDGEVSSASSEP---------------------------------------ILANG--TAHPEANDGGQ-------------------------PPKISEEE--------VEPIKSVRRRQKNNSSK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFSFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYVVYRCRQSINFSLQCAWLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--SSQRIRREVPQPPPPYPPPLHHGPGMSEHSLSPSKRTHQR---SKSDATVSIS------------------------------------LSSNLKRTASNPKVETSQDE--------------PVRLTPQREFIKSLMGIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AAFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FETSSVPVRIPETQIRSTRSVENLPDCGITPDQ-----RASSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEIHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPIFIAAGDIRRRLSEQLAHT-PTTFRKDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAYQVLKQLQIIWEQERVPLWIKPYKILVISSDSGMIEPVVNAVSIHQVKKQSQL---------------LLLDYFRQEHGNFNTEEFLTAQRNFVQSCAGYCLICYLLQVKDRHNGNILLDSEGHIIHIDFGFILSSSPRNLGFETSAFKLTSEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMEKVIQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMNLTEEQLQVLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K881-1", "uniprot_id": "A0A4D6K881_DROME", "id": "A0A4D6K881-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "MNSVISAFKGKKNSNPSCNSPMGSANGTAPVEAKPNNCYQYLRHIREIDTNNKLLSPVVVVAEERPVSKAGSPSTVATMATGVDVVDHCLPTTVRLSVTEALSDLNMNGKAVEPPVTPCTSVGDNANLEVAETWACPPPQATDDEDISEHSTAACTSTSSSSEHSNSTVVHSPTVGESTCDSVSVSVSHPSPSVSQNNTSSATGRMSSPHSQSSLSIACEPHSASTTTLSSLGSDLGNGNGSTVPAFLMAAPVTLPIGGQMPTIKCLPGASSAASTPKHSRYSKPRLSLSRVFNHSMPSVHGRPNLSLAPAGVPGSVNPPKRISTHQRNLSLDFRSMGILLPPVSQVTNNHINHTQHHRNRSLDSALQRIPEVEVSSPNAESENTFCSPSILGATMCSKIATTAATVTSALSPPGTPTPALMSTACTPTIGAVKGNVQHPVPKHEQSISLAAACRSSAVVESCPTLRMRPKSSESVAANGQEMIGVIVSSTGNGSSSSNNSCSSAGSTKKREDLTSLGSDDSGIICGSESDQISLNRICHSHESLDSGEMDADADAEEECVDLMDTTSIDEEYNIMQPDHLCLYPPQAASTELDCRTLRPSRKQKRQQQQVLERKNLPSQNQIESEDSVDAGVDARTRYRVMNMSQAAINVELGTASNEIDPDVNYRESHQDPIADAPSLSTPSVASTASATPSVTPTPIATPTPTESTKNDQVLFKNFFGATKNAIFRTAQSIIENHEKKNAAKQKEQPDHSGTVSLVGSPNGGSSVPQDLVKSPTDISKKKEFFSLLTSSSSIKAAAAAAANSAASTPPATPTEALAANSNSKLQPLSDPSADLKVKERTLNLRLPGDSEGSEGALTKCSSINSIHKLKLPVPGVVKYFISEKAPVSDVLQKPEKGQSGLLRFFESPVFNIHFAVHYLFYSKEPGVLSFIGNKIFSFPDQEVDLYIPQLVVMYIQMDELA-EVLDPYLTIRCRKSVDFSLKCLWLLEAYNYQVDSLGNSHNSSRKSKLALMKEIFSKR-EHKQTQNDLKSAGTG-----GLHVGEPRSVVALAKKTHHR---SQSDATVLLADFRSPHTLSISHRMYQQPPYTTQTLPTTPAKLCLGDLTSGHAFDNGCTCFETVRGQVNGLLGQRTLCSCGAPKTSPQKEFMKALMNVGKNLTSWPSKAEKTSALRMSLNLINKNLPARVWLPLY-----SDIPHHVVRITEEKTAVLNSKDKTPYIIYVEVVEIPD-IYTSPLIPKMMPS-LRHTKSEEHLDGSCLNSHQHLSCSRTSSCSSSQQGTSCRRKKGADVDGGCGDAGPHNSCSNVHSLGGLQFQE-------------------DDVWSQEEDEITAQYLNMRKVSERDTISQISLDS----------------------------------CDSRDQGPPVVFNIGDVRLRHCSNLSCENTKSFSNDPEDPS------------------AAALKEPWHEKEKLIRESSPYGHLSNWRLLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTVSLHQIKKNSNK---------------SLKEYFIDEYGSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDRHNGNILFHSDGHIIHIDFGFILSISPKNLGFEQSPFKLTPEFVEVMGGTSSEHWREFNKLLLVGMMSARKHMDRIINFVEIMRSNAHLPCFKNGCSGTVQNLRKRFHMNLTEQEMERKVEQLVQD-SLKSLSTKLYDGYQYYTNGILXERFFMKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39104-1", "uniprot_id": "PIK1_YEAST", "id": "P39104-1", "name": "Phosphatidylinositol 4-kinase PIK1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHKASSSKKSFDDTIELKKNEQLLKLINSSEFTLHNCVELLCKHSENIGIHYYLCQKLATFPHSELQFYIPQLVQVLVTMETESMALED-----------------------LLLRLRAENPHFALLTFWQLQALLTDLSTDPASYG-------FQVARRVLNNLQTNLFNTSSGSDKNVKIHENVAPALVLSSMIMSAIAFPQLSEVT--------------------------------------KPLVESQGRRQKAFVFKLAR-------------------------SAMKDFTKNMTLKNTLLNKKTSRSKRVSSNRS------------------------------------------------------------------------------------------------STPTSPIDLIDPIKTKEDASFRKSRHSEVKLDFDIVDDIGNQVFEERISSSIKLPKRKPKYLDNSYVHRTYDGKNINRDGSISNTAKALDGNKGDYISPKGRNDENNEIGNNEDETGGETEEDADALNSDHFTSSMPDLHNIQPRTSSASSASLEGTPKLNRTNSQP--------------------------------------LSRQAFKNSKKANSSLSQEIDLSQLSTTSKIKMLKANYFRCETQFAIALETISQRLARVPTEAR-LSALRAELFLLNRDLPAEVDIPTLLPPNKKGKLHKLVTITANEAQVLNSAEKVPYLLLIEYLRDEFDFDPTSETNERLLKKISGNQGGLIFDLNYMNRKENNENRNESTLTSNNTRSSVYDSNSFNNGASRNEGLSSTSRSDSASTAHVRTEVNKEEDLGDMSMVKVRNRTDDEAYRNALVIQSAANVPILPDDSQDRSPELNFGSNLDEVLIENGINSKNIHSQTDALADQMRVSAVMLAQLDKSPQQLSESTKQIRAQIISSMKEVQDKFGYHDLEALHGMAGERKLENDLMTGGIDTSYLGEDWATKKERIRKTSEYGHFENWDLCSVIAKTGDDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHSIKKALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLLQVKDRHNGNIMIDNEGHVSHIDFGFMLSNSPGSVGFEAAPFKLTYEYIELLGGVEGEAFKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQPCFDAG-EQTSVQLRQRFQLDLSEKEVDDFVENFLIGKSLGSIYTRIYDQFQLITQGIYS-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . . : : : * * :* :: : : . . : :. . : . * .. . : ::: .: :. : * : :: : : : : *:: : . :. . * .. ::. . * : . . : . : : . : . : : . .:::: . . : . : :* :* :.:.*: *:: . . * .* *:*:.***.* :* *::* :. :: **** :*.**:: :* :. : .: . . : .:. : :. .: . .: :: : . . . . . :: : : : . * .::...* .. : ::* : ..: . .* * : * * * * . **: * ***: ** * *.*.* ******* :* *::: : ** :*:* :*:: **: * ::*::*.: *::*:*.:** * ::* .*. . : ** **..* *.*.::.*************::. :**: ******:** ** .:*** :.**** *:::::** ..: :. : * .: : **: ::::.: ***:.. ***. . * :*::**::.::*:::: **::: . *: *: *::** :* *:** ", "identical_positions": 148, "similar_positions": 251, "identity": "8.29%" }, { "cls_id": "homologset.agr.FB:FBgn0004374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE01-1", "uniprot_id": "D3ZE01_RAT", "id": "D3ZE01-1", "name": "Kinesin-like protein KIF14", "aln": "MSVHTSHSRHNIG-SLEVSSSQKISASSGLVHSSRLELRLKSDMSECENHDPLANAGTKTIDINSTYVISACKKARETPATPDPG-RLTLQRRTTWN-KESSLLGSESGHPTGRTADTSLRLQRRPLARADYGEKWETSNP--------VGGNPGSKSASQKGRTEAKLVN--NDSCALSSVVSEKDS---NDTGLTKRKDPCPALSTSNEKVTVKNPNSRAPIGSQRQTEAMRSGHLVVQPVENKADIQVSGGGNSHHGNAGKGIAKHTSTFGSSETRTPAKCVSEHRSAPRHDLPPPKSPALSTQKNNGKDIAKHVSTFRNSSSETQTPAKCVLEHRWAPRHGLPPPKSPALSTLKNRIASPRVKPRPKSSLLANK--SSQESTLPPEEKSTVQNTFTEPDSLKVENSQVTVAVRVRPFSKREKTEKASQVVFRNGEEITVEHPDMKQIYSFIYDVAFWSFDECHPGYANQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLN-------------EEPGIIPRFCEDLFAQIAKKQAS-EVSYHLEMSFFEVYNEKIHDLLVCK-------------GENGQRKQPLRVREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHR----------ITSRINLIDLAGSERCSTAHSSGERLKEGVSINKSLLTLGKVISALSEQANGKR----------VFIPYRESTLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYATQARLIVNVAKVNEDMNAKLIRELKAEIEKLKAAQ----------KSSRNIDPERYRLCR----QEISSLRMKLHQQERDMAEIQRVWKEKFEQAEKRKLQETKELQKAGVTFQMDN--HLPNLVNLNEDPQLSEMLLYMVKEGITTVG-----KHTPNSSHDIQLSGVLIADDHCTIRS-YGGTVSIVPAG-EAKTYVNGMHISEPTVLHHGDRVVLGGDHYFRFNHPVEVQKGKKTS-RNNLTS-EGPKDFEFAKNELLAAQRSRLEAEIKDAQLKAKEEMMQGIQIAKEMAQQELSSQRAAYENKIRALEAELREESQRKRLEEINNQKASHKIEELEKAKQHLEQEVYVNKRRLEMETLATKQALEDHRIRHARILEALEREKQKIAEEVQILQENRGNRNKTFTIQPNWSSMKLSTMIQEANAISDKFKKHYVFGRHDASDKG-RSDPSVRVRNLQLGISTFWNLEKFESKLAAMKDLYESNSGTRGEDVFCDPEDEWEPDITSTPVSSLSRRRSRSLMKNRRVSGCLHDI--HPIQSMHPSHTSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFLGQSFDEEKTIADSLINNLLKLYNGVIAISKAHEEQDEESQDNVFS-DRAAQALTIQVACAFEQLVVLFKHWLDDFPPCSGSARLEEELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKVTEIIQQAVGHVAQLAVLKGSKLCVLEDSNK--VSSAQELMAALQDGTASGMRSLLDSGLETAQELRQDVSRQSAPEEVTRQMKANAVELVGSLENIFAEWRTKSFRTQVEEG--SRQQGSKVLNLASEFLKLKSCLQQTIEMVVSALRGCPSDLRCLRSCTETICGLAHKLHGGFSALSDSAGSCGNEQPRAVWEELESLAKSLLLCFEHGERPSFLKPWESCTSNSTEEQRESDRADCS----RSVPGRACEPHRDPTPAESSGDGTPSRIQWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "L0N7N1-1", "uniprot_id": "KIF14_MOUSE", "id": "L0N7N1-1", "name": "Kinesin-like protein KIF14", "aln": "MSVHTSHSRHNIG-SLEVSSSQKISASSGLVHSSRLELHLKADMSECENHDPFVNAGSKTIDINSTYVISACKKTRETPVTSDPR-RLSLQRRATCGDRESSLLGSELGN--RRTADTSLRLQRR-HGRADYVGKWETLNP--------VGGNPGSDSASQASRTEAKGVN--NDTRVLSSVVSVKDS---NDTGLTRCKDPGPPVGASNEKVTVKDTNSRAPVGSQRQTEAMRSGHLVVQLTESKSDTPVSGGRNSHRGNAGKDTAKQVGTFGSSDTRTPVKCVLEHRWTPRHDPPPPKSPALSTPKNNGKDIPKHGSTFRSASSESRTPVKCVPEHRWTPRHDLPPPKSPALSTLKNRIASPRVKPRPKSSLFANKRESSRESTLPPEENSLVQKTFTEPDSLKVENSQVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYDVSFWSFDECHPGYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLN-------------EEPGIIPRFCEDLFAQIAKKQTS-EVSYHLEMSFFEVYNEKIHDLLVCK-------------GENGQRKQPLRAREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGEEHDHR----------ITSRINLVDLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGKR----------VFIPYRESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVNIAKVNEDMNAKLIRELKAEIEKLKAAQ----------RSNRNIDPERYRLCR----QEITSLRMKLHQQERDMAEIQRVWKEKFEQAEKRKLQETKELQKAGVTFQMDN--HLPNLVNLNEDPQLSEMLLYMVKEGVTTVG-----KHTPSSSHDIQLSGVLIADDHCTIRN-FGGTVSIVPAG-EAKTYVNGTHISEPTVLHHGDRVVLGGDHYFRFNHPVEVQKGKKLSSRNNLTTSEGPKDFEFAKNELLTAQRSRLEAEIKDAQLKAKEEMMQGIQIAKEMAQQELSSQKAVYERKIQALEAELREESQRKRLEELNNQKASHKIEELERAKQHLEQEVYVNKRRLEMETLATKQALEDHRIRHARILEALEIEKQKIAEEVQMLQENRGNRDKTFTIQPNWNSMKLSTMIQEANAISDKFKKCYIFGRHDASDKG-RSDTSVRVRNLQLGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCDPADEWEPDITSTPVSSLSRRRSRSLMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFLGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVACAFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKVMKIIQQAVQCVGQLAVLKGSKLCVLENSSK--VSSTQEFMAALQDGVTSGMKSLLDSGLETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEG--SRQQVSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCG----KSGPRRACEPHGDATPAVSSGDCTPNRIQWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15058-1", "uniprot_id": "KIF14_HUMAN", "id": "Q15058-1", "name": "Kinesin-like protein KIF14", "aln": "MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKVRDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRN-KESSLLVSELEDTTEKTAETRLTLQRR--AKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGNLYHRSIGKEIAKTSNKFG--------------------------------------------------SLEKRTPTKCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFS-------------EEPGIIPRFCEDLFSQVARKQTQ-EVSYHIEMSFFEVYNEKIHDLLVCK-------------DENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHR----------ITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRS----------VFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQ----------RNSRNIDPERYRLCR----QEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDN--HLPNLVNLNEDPQLSEMLLYMIKEGTTTVG-----KYKPNSSHDIQLSGVLIADDHCTIKN-FGGTVSIIPVG-EAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPIS-EGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKS-SSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKGVPKRVYELHG-SSPAVSSEECTPSRIQWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIP4-1", "uniprot_id": "Q9VIP4_DROME", "id": "Q9VIP4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNKSTPVRQRIQQFQTRGVHKSTPASEMRKKVLMTRAEDREHRDRPEQLLN--------------------------------------------------------TAFSGSTPQPKPKPTALNACYTPSSLYRNANSTPGRAKTPGTGKSSCSRTKERDSLMESCLSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAG-----------VTHFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRG----------KADHPVDFQLAHQEILQKQEQQLRSELEAEKRAALTKIEQ-----------ERAQHARDFEERLQCLELEQFKYKCNSEMLETER------------------------------QALALAQQQEHTPLRHEDAVSTP-AQKSTILEDIQRIMLNPSEE----------SLHKTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATTIFQSVEVDWEPLDADLNETLSDTHNSSRIALN--LSAMKDVLLNKPLKRLLNASSS-KSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTLVQQELQIMQRSAQRLRRHCEAALLERENHQD-------------------------------------------NGVLAVSLQEALARMDTVLNGMHTSLARAEATACVTSPTKTQKAVRFLID----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... .*: . * *. * . : : . : : : . : : : . :. : : * . .* . . . * .. . :: *.: * :.*: ..*** .*:*: ::. . : .*.. * : * ** ::* * : :* *:.*:* * **:: ****:*:**************:***:. :*.*******.:** :: ::. ::. .:*:*:**:********* : :: *:: .*:.****: **** ** : *.**: ::.** :**.*****:*.**********:*.:*:. *. . :* . * *:*.*:******* *.: :.*:*::****************:**::. : .*:*****.*****:*.*******.*:**:***: : :***:***** :** *** .****. : *:**:*:**: :**: : ...* *.: : *: :** :* ::**:::. *: * **:::**.:: .* : *:: *: ::: : . ****. ** ** *:*:: :* . :* ...*. ** *.* *:* :**:*. **.: ::* . : :***** : : * ****:::**.****:.:*. *:* . : * **::*::*:* *..:*.:*:: : * :: * * :.: :* :::.** * : . ...: * :. ::** * *. :** :.: :*..* :::* : * .:. . * . *::**. . ::. * : : .*: . : : : : *:.: * :: * ::: *.: . * . :*** :. : . :.* : * :*. . : :*:: : : :* :.. : *. * * : *.*: . : : :* .. *:.:. :: : : : : .:* : *: ** : * .::: . :: .*:* .:: * . *:** : : ", "identical_positions": 320, "similar_positions": 358, "identity": "18.04%" }, { "cls_id": "homologset.agr.FB:FBgn0004378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAB8-1", "uniprot_id": "F1MAB8_RAT", "id": "F1MAB8-1", "name": "Kinesin-like protein KIF11", "aln": "----------------------------------MASQPSSSSKKKEEKGKNIQVVVRCRPFNLAERKANAHSVVECDHA--RKEVSVRTAGLTDKTSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEVYTWEE----DPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLSPS-------SDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTID----GEELVKIGKLNLVDLAGSENIGRSG-AVDKRAREAGNINQSLLTLGRVITALVERTPHIPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIMNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE---ESFRAMNGKVTVQEEQIAELAEKIGVLEEELSKAAELFTDS-------EKELNQCKSDLQTKTQELETTQKHLQETKLQLVKEEYVSS--ALERTEKKLHETASKLLNTVKETTRDVSGLHSKLDRKRAIDAHNAEAQESFGRSLSS----------LFNNMEELIRDGSEKQKAMLDVHKALFGNLMSSSVSALDTISTTALESLMSIPENVLARVSQISDMILEEQSLAAQSKTVLQGSIDELVTNLFTSLKTIIAPGVVSILNINRQLQHIFRASVTMAEKVEDQKREIDSFLS---ILCNNLHELRENTVSSLVESQKLCG-NLTEDLKTIKETHSQELCQLSS-SWAERFCALEKKYANIQKPLNSIQENTERKSTDIINKTTVHSKKILADSDGLLQELRHFNEEGTQLVEDSVGHCGSLSSNLETVSQEITQRCGTLNTSTVHFSDQWASCLSKRKEELQNLMEFVNGCCEASSSEITEKIRGHRAAIESQHSSFVVQITSDEEKFKAGSLELDKTIKTGLTKLNCFLQQDLKLDIPTGMTPERKNYLYPST-LVRTEPREQLLDQLQKKQPKPLMMLNCSESSKE-TSQDMEEDREVLEQSTEELVSQEPCVHTSADCSSSGGVPFFQHKKPHGKDKENRGLNPVEKG-KVEEASEHSISKSRLPLRASINLC--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9P6-1", "uniprot_id": "KIF11_MOUSE", "id": "Q6P9P6-1", "name": "Kinesin-like protein KIF11", "aln": "----------------------------------MASQPSS-LKKKEEKGRNIQVVVRCRPFNLAERKANAHSVVECDHA--RKEVSVRTAGLTDKTSKKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEVYTWEE----DPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLSPS-------SDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTID----GEELVKIGKLNLVDLAGSENIGRSG-AVDKRAREAGNINQSLLTLGRVITALVERTPHIPYRESKLTRILQDSLGGRTRTSIIATISPASFNLEETLSTLEYAHRAKNIMNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE---ESFRAMNGKVTVQEEQIVELVEKIAVLEEELSKATELFMDS-------KNELDQCKSDLQTKTQELETTQKHLQETKLQLVKEEYVSS--ALERTEKTLHDTASKLLNTVKETTRAVSGLHSKLDRKRAIDEHNAEAQESFGKNLNS----------LFNNMEELIKDGSAKQKAMLDVHKTLFGNLMSSSVSALDTITTTALESLVSIPENVSARVSQISDMILEEQSLAAQSKSVLQGLIDELVTDLFTSLKTIVAPSVVSILNINKQLQHIFRASSTVAEKVEDQKREIDSFLS---ILCNNLHELRENTVSSLVESQKLCG-DLTEDLKTIKETHSQELCQLSS-SWAERFCALEKKYENIQKPLNSIQENTELRSTDIINKTTVHSKKILAESDGLLQELRHFNQEGTQLVEESVGHCSSLNSNLETVSQEITQKCGTLNTSTVHFSDQWASCLSKRKEELENLMEFVNGCCKASSSEITKKVREQSAAVANQHSSFVAQMTSDEESCKAGSLELDKTIKTGLTKLNCFLKQDLKLDIPTGMTPERKKYLYPTT-LVRTEPREQLLDQLQKKQPP--MMLNSSEASKE-TSQDMDEEREALEQCTEELVSPETTEHPSADCSSSRGLPFFQRKKPHGKDKENRGLNPVEKY-KVEEASDLSISKSRLPLHTSINL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52732-1", "uniprot_id": "KIF11_HUMAN", "id": "P52732-1", "name": "Kinesin-like protein KIF11", "aln": "----------------------------------MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPV--RKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEE----DPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPS-------SDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTID----GEELVKIGKLNLVDLAGSENIGRSG-AVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE---ENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDN-------KNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITS--ALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS----------LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLS---ILCNNLHELQENTICSLVESQKQCG-NLTEDLKTIKQTHSQELCKLMN-LWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPST-LVRTEPREHLLDQLKRKQPELLMMLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTLERS-KVEETTEHLVTKSRLPLRAQINL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46863-1", "uniprot_id": "KL61_DROME", "id": "P46863-1", "name": "Kinesin-like protein Klp61F", "aln": "---------------------------------MDISGGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGP--REVVTRHT---LDSKLTKKFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWED----DSDIGIIPRALSHLFDELRMMEVEYTMRISYLELYNEELCDLLS---------TDDTTKIRIFDDSTKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIE----GEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAE---ETYGEITLKLESQNRELNEKMLLLKALKDELQNKEKIFSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVA--SHMKTEQVLTTQAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHS--QAFVAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKLE---QLG-AMSLPDAEELQNLQEELANER-ALAQQEDALLESMMMQMEQIKN-LRSKNSISMSVHLNKMEE----SRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVDARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQRQQLQICEQELVRFQQSELKTYAPTGTTPSKRDFVYPRT-LVATSPHQEIVRRYR-------QELDWSDLDTTATIDECSEGEHDVSMHSVQELSETETIMNSTPIEPVDGVTVKRGCGTTRNSNSNALKPPVATGGKRSSSLSRSLTPSKTSPRGSPAFVRHNKENVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28742-1", "uniprot_id": "KIP1_YEAST", "id": "P28742-1", "name": "Kinesin-like protein KIP1", "aln": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSG-AENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQ----SEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNN---YNSKCSEVIKGVTEELTR-------------NVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQS------HQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFN---SLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. **:* ** *. * * : ::. :: : . .. *.: ** **..:.* *: .. :.*:: *****:***********.** *: . : . *****.* .:*.:* *:::::* **:***:* ***. .* . ::::**: :: .::::*::** ::. .: ::* :* :*..*:* * *****:**::. :: * . .::::***************:.::* . *.:*: **:*********.***::: *:*********:**:**** *:*.*******. .:*** ****** ***.* *.*:***.*:*.: :*:* :**::*:.** :*:*:*::::: : : . : *: :: : : .::: . .: ::* .:: : : : .*: . :: : ::: . * . . *:..::. : : . . . : : : . . . : .. : :. . . .: .: : * : : :: : ..: :.:: * :: :: . .. : . :::. * : : : : : : :: . :. : :: . : :. ::: . . : . .: . : . : . . :. .:. . : :::: : : . : . . : : . : :. :* : :. . . :.. * : :: : * . : : : :. . . : : : . . .... . : : . ", "identical_positions": 172, "similar_positions": 312, "identity": "15.01%" }, { "cls_id": "homologset.agr.FB:FBgn0004379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WD7-1", "uniprot_id": "KI18A_MOUSE", "id": "Q91WD7-1", "name": "Kinesin-like protein KIF18A", "aln": "MSGTEEDLCHRMKVVVRVRPENTKEKA---------------------------------------------------------VQFCKVVHVVDKHILSFDP-------KQEEISFFHRKKTTNFDIT----------------KRQNKDLKFVFDAVFDETSTQMEVFEHTTKPILHSFLNGYNCTVFAYGATGSGKTHTMLGSAAEPGVMYLTMLDLFKCIDEIKEEKECSTAVSYLEVYNEQIRDLLTNSGP---LAVREDSQKGVVVQGLTLHQPKSSEEILQLLDNGNKNRTQHPTDVNAVSSRSHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASVSGAKGSRFVEGTNINKSLLALGNVINALANTKR-RNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSLFYDDTYNTLKYANRAKEIKSS-LKSNVLNLNSHISQYVKICNMQKAEILMLKEKLKAYEEQKALSDRNDCAKLVHSNPEDRETERFQEILNCLFQNREGIRQEYLKLEMLLKANALKSSYHQQCHKQIEMMCSEDKVEKATCKRDHRLEKLKTNSCFLEKKKEEVSKQFDENTNWLHRVENEMRLLGQNGDIPEALNKELHCHHLHLQNKELKTQMAHMTALACLQEQQHKQTEAVLNALLPVLRKQYWKLKETGLSNAAFDSDFKDIEHLVERKKVVAWADQTNEHSNRNDLPGISLLMTFPQ-------------LEPIQSISCCTSVSDPNVLKLTP-QRRTRRKIIPSPLKVQHTQKSALSESTQLNDSFSKELQPIVYTPEDCKK-AQDLFPS-LTRTSSQ-------SANVMNDNSQKALCRIESPLSR-TECKQG-LYSTSTLCDSIRGLKNKWPEQEPLAS-SKSSVHRIESSSFSTKDSMPESAGVPSYMAMTTAAKRKWKQMSSTSNASIKSDESCGFAKRIRRDNSSVKPMQENRLKVG-------------------YKRNTNKTN----------SNMLRKFRRNTSKENVQ---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JW74-1", "uniprot_id": "A0A0G2JW74_RAT", "id": "A0A0G2JW74-1", "name": "Kinesin-like protein", "aln": "MSGTEEDLCHHMKVVVRVRPENTKEKA---------------------------------------------------------VQFHKVVHVVDKHILVFDP-------KQEEISFFHRKKTTNFDIT----------------KRQNKDLKFVFDAVFDETSTQMEVFEHTTKPILHSFLNGYNCTVFAYGATGSGKTHTMLGSTAEPGVMYLTMLDLFKCMDEVKDEKECSTAVSYLEVYNEQIRDLLTNSGP---LAVREDAQKGVVVQGLTLHQPKSSEEILQLLDNGNKNRTQHPTDMNAASSRSHAVFQIYLRQQDKTASINQNVHIAKMSLIDLAGSERASISGTKGTRFVEGTNINKSLLALGNVINALADTKR-RNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSLFYDDTYNTLKYANRAKDIKSSQLKSNVVNLSSHISQYVKICNMQKAEILMLKEKLKAYEGQKALTDRNDCAKLVHSNVEDKEIERFQEILNCLFQNREGMRQEYLKVEMLLKENELKSSYHQQCHKQIEMMCSEDKLEKATCRRDHRLEKLKSNRCVLEKKKEEMLKQFDENTNWLHRVESEMRLLGQNGDIPEGLNKDLHCHHLHLQNKDLKTQMGHMMTLAALQEQQHGQTEAVLNALLPVLRKQYWRLKETGLSNAAFDSDFKDIEHLVERKKVVAWADQTAEHSNQSDVPGTSLLMTFPQ-------------LGPIQSIPCCSSMSDPSILKITP-QRRTKRKLIPSPLKVKHTQKSALSERTQLNDSFSKELQPIVYTPEDSRRTVQDLSPP-LARASSH-------SANGMNDNSLKALCRTESPLSR-TECKEG-LYSTSAICDGIKSLKNNLP--EPLPS-SKSTLHRVESSSFPTKDSRSVSTSVPSYMAMTTAAKRKWKFMSSTSDASLKSDESCGLAKRIRQDNSSVKLIRENRLRAIKKPPTKQIQTCLENLEETLQKKMYNKKNQCPLYGICFFRNVFQVCERRPSKTVCSNIFSSKMRLLYLK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NI77-1", "uniprot_id": "KI18A_HUMAN", "id": "Q8NI77-1", "name": "Kinesin-like protein KIF18A", "aln": "MSVTEEDLCHHMKVVVRVRPENTKEKA---------------------------------------------------------AGFHKVVHVVDKHILVFDP-------KQEEVSFFHGKKTTNQNVI----------------KKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR-KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSS-LKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQ-------------LGPVQPIPCCSSSGGTNLVKIPT-EKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTVTLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSKCKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNSSLTADVNSGFAKRVRQDNSSEKHLQENKPTME-------------------HKRNICKIN----------PSMVRKFGRNISKGNLR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFD6-1", "uniprot_id": "KI18B_MOUSE", "id": "Q6PFD6-1", "name": "Kinesin-like protein KIF18B", "aln": "--MVMAVEDSVVRVVVRVRPPTPKELE---------------------------------------------------------SQRRPVIQVVDERMLVFDP-------EECDGGFPGLKWSGSHNGP----------------KKKGKDLTFVFDRVFGEMATQEDVFQHTTHNILDSFLQGYNCSVFAYGATGAGKTHTMLGREGEPGIMYLTTMELYRRLEARQEEKQFEVLISYLEVYNEQIHDLLEPKGP---LTIREDPDKGVVVPGLSFHQPASAEQLLEMLTRGNCSRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQALRVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKG-RKSHVPYRDSKLTRLLKDSIGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLT-LKSNVISVDHHISQYATICQQLQAEVAFLREKLQMYEAGAQA-----------------------------LQQQCSPQPPTLSIPQSLSSSSLQPGPSSQSSTLECHAKNETLQEESLGSDAQGQEIVEESASEQEQCPQDK------------QCPTQKPEPN----LPGSP--------------SPSVQAKPGTGQHSPQKQDADHSKQLALQVLRLAQRQYSLLQAANLLTPDMISEFETLQQLVLEESVDHRAESPRSPALARGDPLAQALCSESK---------SSGYCGPVTRTMAKQLNGLTHTLGAPLAPDCTSDKTFQKPTKEKKRKLTPEEPGSLPAPNLEMKRQRQSFLPCLRRGSLPKAQPCSEPRTPKR--------ERASSPSPSSRVCPATVIKSRVPLGPSALQNCSTPLALPTRDLNTTFNVSEESPS-KPSFQEFVDWEKVSPELNSTDQPFLPSAPVFIFT-KGRKP--SLPAVTASK--KRRTMRPSVSRGRSCIARLHSSTLKKP--------------------NRPFTVPEPP--------LSPHCLDDQRTPKGLTGVTESY----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLL9-1", "uniprot_id": "KI18B_RAT", "id": "Q4KLL9-1", "name": "Kinesin-like protein KIF18B", "aln": "--MVMAVEDSVVRVVVRVRPPTPKELE---------------------------------------------------------SQRRPVIQVVDERMLVFDP-------EECDGGFPGLKWSGSLSGP----------------KKKGKDLTFVFDRVFSEVATQQDVFQHTTHNILDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIMYLTTMELYRRLEACQEEKQFEVLISYLEVYNEQIYDLLEPKGP---LTIREDPDKGVVVPGLSFHQPASAQQLLEMLTRGNCSRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQALRVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKG-RKSHVPYRDSKLTRLLKDSIGGNCRTVMIAAVSPSSLTYEDTYNTLKYADRAKEIRLT-LKSNVISLDHHISQYATICQQLQAEVAALREKLQTYEAGAQA-----------------------------LQQR-SPQPPKLSIPQNLSSSPLQPGHSSQSCAPEFHAKYDAPQEESLGTDSQGQGTVEENAPEQEQPPQDK------------QFPTQMPEPN----LPGSP--------------CPTVQAKQGMNQHSLQRLDAEHSKQLALRVLRLAQRQYSLLQAANLLTPDMISEFETLQQLVLEESMEHGAESPRSPGLARGIPLAQELCSESK---------SSRYCGPVTRTMAKQLSGLTHTLGIPLAPDCTSDKTSQKPTKEKKRKLNLEEPGSLPAPSVEMKRQRQSFLPCLRRGSLPKIQPSSEPRTPKG--------ERASSPSPSSRVCPATVIKSRVPLGPSALQNCSTPLTLPTRDLNTTFNVSEESPS-KPSFPEPIDWEKVSPELNGTDQPFLPSAPVFIFTTKGRKP--SLPTTTASK--KRRTVRPSVSRGRSCIARLPSSTLKKP--------------------DRPFTVPDPP--------LSLHCLDDHQVIRD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86Y91-5", "uniprot_id": "KI18B_HUMAN", "id": "Q86Y91-5", "name": "Kinesin-like protein KIF18B", "aln": "----MAVEDSTLQVVVRVRPPTPRELD---------------------------------------------------------SQRRPVVQVVDERVLVFNP-------EEPDGGFPGLKWGGTHDGP----------------KKKGKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLEPKGP---LAIREDPDKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKG-RKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLS-LKSNVTSLDCHISQYATICQQLQAEVAALRKKLQVYEGGG--------------------------------------QPPPQDLPGSPKSG---PPPEHQPCTPELPAGPRALQEESLGMEAQVERAMEGNSSDQEQSPEDEDEGPAE------EVPTQMPEQNPTHALPESP--------------RLTLQPKPVVGHFSARELDGDRSKQLALKVLCVAQRQYSLLQAANLLTPDMITEFETLQQLVQEEKIEPGAEALRTSGLARGAPLAQELCSESIPVPSPLCPEPPGYTGPVTRTMARRLSGPLHTLGIPPGPNCTPAQGSRWPMEKKRRRPSALEADSPMAPKRGTKRQRQSFLPCLRRGSLPDTQPSQGPSTPKG--------ERASSPCHSPRVCPATVIKSRVPLGPSAMQNCSTPLALPTRDLNATFDLSEEPPS-KPSFHECIGWDKIPQELSRLDQPFIPRAPVPLFTMKGPKPTSSLPGTSACK--KKRVASSSVSHGRSRIARLPSSTLKRP--------------------AGPLVLPELP--------LSPLCPSNRRNGKDLIRVGRALSAGNGVTKVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSW5-1", "uniprot_id": "Q9VSW5_DROME", "id": "Q9VSW5-1", "name": "", "aln": "---MPSEQHTNIKVAVRVRPYNVRELE---------------------------------------------------------QKQRSIIKVMDRSALLFDPD------EEDDEFFFQGAKQPYRDIT----------------KRMNKKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSEAHPGLTYLTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLLTKSGP---LKLRED-NNGVVVSGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERKT---DTKRTVKLSMIDLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLADG----LKHIPYRDSNLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTT-LKQNVLKSKMPTEFYVKKIDEVVAENERLKERNKALEAKATQ-----------------------------LERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRSKIKNINYRQTLKKELEEFRKLMCVDQRVCQEDFRRFAN-----YMSTLTSQMEKYKEELPSWLS---------------KMEIAYQDLESLKREVNKSKAYQILIVYVKYKDLELQLTKQNIFNNHVNAINQELVENLDLMRKSFRTACEVLNQTYDRLEDGQK--------------------LTPEIEAVFERLLRKMRFADSEANTKMAEMNPLAVPVALRSSAQEEEEPTCSLTASAKKRQRQAAQSDDDLHLSMEDFDSQDTESDSEE--------------------LHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSARKALTATVTKPRTVQQRLVSDLISDQNVRGGNEKIKKALLKSNHFTAQGLQRTLAAASLAKENVKYNANYVRKSPRALMAKALAGTSTLAR--------------------KPLGSASKE---------PPLVKFNRAASFRLKK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53086-1", "uniprot_id": "KIP3_YEAST", "id": "P53086-1", "name": "Kinesin-like protein KIP3", "aln": "-MNVPETRQSSIVVAIRVRPFTSMEKTRLVNEASGAEANFPGLGDSSLILPMSNNSDSDIDIDAEEGSTRSKRNSLLRRKVIRPEGIRKIVDCVDDRMLIFDPADRNPLNKVSDQVLNSMRARATKATASSINNSNATNKFSSQRRRHGGEIKFVFDKLFDETSSQARVYKETTSPLLDSVLDGFNSTVFAYGATGCGKTYTVSGTPSQPGIIFLAMEELFNKITDLKDEKDFEISLSYLEIYNERIRDLLKPETPSKRLVIREDTQNHIKVANLSYHHPNTVEDVMDLVVQGNINRTTSPTEANEVSSRSHAVLQIHIMQTNKLVDLTSQHTFATLSIIDLAGSERAAATRNRGIRLHEGANINRSLLALGNCINALCLNDGSRSCHIPYRDSKLTRLLKFSLGGNCKTVMIVCISPSSSHYDETLNTLKYANRAKEIKTK-IIRNQQSLSRHVGSYLKMITEQKRQIEELRERE----------------------------------------------------EKMISLKLTKYKLNKEKIQLAINECVNRVQQTYAGVETYQVAKTLKSLILCKRRFLQM----------------------------------------------VKLEVDNLILLFEREESTAAEMQPVISNCRMISGQLYNKIHELEMKFDETDTLSSVIHQVHSIDLNKLREMEDWDETYD-----------------------------LVYLESCLNQISELQRNEILVNSSIMTEKLMSDPG-LNSRFKFLSKWLMNRTPNIESIIQDLVHIDEEFESFARTFIANPDSNFTNT------------------------NINIINTTAADLAVPAETLQRQNFSQKKVKWTSPDLSPS------PMIEPQPELEPELHQDQDAIASEVDVSMQDTTFNEQGPSTPSAPTTAVPRRKMRSSLLTHQSLLATARK----------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:**** . * ::. :* * *:* : : : :: . .:.: ** :*. :: :::. * :: :.*:*:*.:*:.*****.***.*: * .**: :*: .*: : .: : . :** *:***:: :** . * * :*** :: : * .* : :::: :: ** ** **: * ******::*:.: :: . ..:*:*********: : * *: **:.**:***** * :* *. *:***:*:***:** *:****:*:*:. :* ** *::* ******.***.*: . : * . . * . : *::: . : :: : . : .. . : : : . :.:: : * . . . : . . .. . . . . : . : . . . : . .: ", "identical_positions": 121, "similar_positions": 155, "identity": "11.62%" }, { "cls_id": "homologset.agr.FB:FBgn0004380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y496-1", "uniprot_id": "KIF3A_HUMAN", "id": "Q9Y496-1", "name": "Kinesin-like protein KIF3A", "aln": "MPINKS------EKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDS-SNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRR---GKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTEESLRQSL-MKLERPRTSKGKARPKTGRRKRSAKPETVID---------------SLLQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28741-1", "uniprot_id": "KIF3A_MOUSE", "id": "P28741-1", "name": "Kinesin-like protein KIF3A", "aln": "MPINKS------EKPESCDNVKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDS-SNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEVSGSDISGSEEDD-EEGELGEDGEKKKKRRDQAGKKKVSPDKMVEMQAKIDEERKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRRRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPQDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKERDPFEVDLSHVYLAYTEESLRQSL-MKLERPRTSKGKARPKMGRRKRSAKPETVID---------------SLLQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AP89-1", "uniprot_id": "A0A8I6AP89_RAT", "id": "A0A8I6AP89-1", "name": "Kinesin-like protein", "aln": "MPINKS------EKPESCDNVKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDS-SNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEVSGSDISGSEEDDNEEGELGEDGEKRKKRR---GKKKVSPDKMMEMQAKIDEERKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPQDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKERDPFEVDLSHVYLAYTEESLRQSL-MKLERPRTSKGKARPKTGRRIQAWKNPVVILRNKKTEQCFLRGLQLSVLDSNKESP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VRK9-1", "uniprot_id": "Q9VRK9_DROME", "id": "Q9VRK9-1", "name": "Kinesin-like protein", "aln": "MPQEEANAGTTAQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTADDELEAPLEIELESS--------------TIQAVEKKPKKKRE-KTDAEKEELAKRKNE---HQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKHISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRSKSARPRTS-GVPRPTTARRY-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::: : :. :**:**** **:::.* * .*:***::. :*** *.:: :******: **.**. *:*:*:* *****:*.*********:**********:**.* * :*:***:***********: : :*******:************** : ********:**::****.***:****::.** **:***:****:**:.********:**:* ** * .. *******:**********:** *:***************.***************:*********************:***.*.*** ** *********.*****:*: :***:*******:**:** .*:*:****:.:. . *..**:* :.*: * . : :** .: :* * * * *:** * : * ::*:: :*: *:::* :** :** *::*** :** **: ** ***:* ***::.: * *:: *::* **:****:*::**: : * ***:::* ***..***:** ******* **: ****.***** * *:::.::*::**.**::*.***********************: .. ... ::* :*******:*. :.: :.: * ***** * .**. .** ", "identical_positions": 399, "similar_positions": 165, "identity": "54.58%" }, { "cls_id": "homologset.agr.FB:FBgn0004381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAF7-1", "uniprot_id": "A0ABK0LAF7_RAT", "id": "A0ABK0LAF7-1", "name": "Kinesin-like protein", "aln": "-MSKLK---------SSESVRVVVRCRPMNGKEKAAAYDKVVDVDVKLGQVSVKNPKGTS-HEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITVECSEVGLDGENHIRVGKLNLVDLAGSERQAKTG--------------------------AQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS----GGGGE---------EEEEEGEEGE-------EEGDDKD----DYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPI---TRLEN--QQMMKRPVSAVGYKRPLSQHARMSMMIRPEP--RYRAENIMLLELDMPSRTTRDYEGPAISPKVQAALDAALQD--EDEIQVDASSF----------ESTAN-------------RKAK-ARPKSGRKSGASSSSSG------------NPASQFYPQSRGLVPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61771-1", "uniprot_id": "KIF3B_MOUSE", "id": "Q61771-1", "name": "Kinesin-like protein KIF3B", "aln": "-MSKLK---------SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTS-HEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTG--------------------------AQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS----GGGGE---------EEEEEGEEGE-------EDGDDKD----DYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPI---TRLEN--QQMMKRPVSAVGYKRPLSQHARMSMMIRPEP--RYRAENIMLLELDMPSRTTRDYEGPAISPKVQAALDAALQD--EDEIQVDASSF----------ESTAS-------------RKPK-ARPKSGRKSGSSSSSSG------------NPASQFYPQSRGLVPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15066-1", "uniprot_id": "KIF3B_HUMAN", "id": "O15066-1", "name": "Kinesin-like protein KIF3B", "aln": "-MSKLK---------SSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTA-HEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTG--------------------------AQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS----GGGGE---------EEEEEGEEGE-------EEGDDKD----DYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPI---TRLEN--QQMMKRPVSAVGYKRPLSQHARMSMMIRPEA--RYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQD--EDEIQVDASSF----------ESTAN-------------KKSK-ARPKSGRKSGSSSSSSG------------TPASQLYPQSRGLVPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QN54-1", "uniprot_id": "KIF3B_DANRE", "id": "F1QN54-1", "name": "Kinesin-like protein KIF3B", "aln": "-MSKSK---------SSESVKVVVRCRPMNEKERVANFNRVVSVDVKLGQVAVCNPRGASSHEHPKVFTFDSVYDWNSKQMELYDETFRPLVDSVLFGFNGTIFAYGQTGTGKTYTMEGVRNDPERRGVIPNSFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQARRLELKERPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSELGPDGENHIRVGKLNLVDLAGSERQTKTG--------------------------AQGERLKEATKINLSLSALGNVISALVDGRSTHIPYRDSKLTRLLQDSLGGNARTVMVANIGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKEQLEKRSGRKRRRRRRRRVGEGGEEFEDGEDE---------EDDDDDDEDE-------EEGVDADKNIADYWHEQQEKLEKERRAIMEDHSLVAEEKQRLLKEKERKMTDLHKEKEASEMLTAKVKAMESKLLVGGKNIVDHTNEQQKVLELKRQEIAEQKRREREMKQEMECRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQSVKSEIQDAQDEHVKYRQELEQTQNELTRELKLKHLIIENFIPMEEKNKIVTRATFDEEDDLWKMTPI---TRIQNSDHQMMKRPVSAVGYRRPLSQHARMAMLMRPDV--RYKAENILLLELDLPSRTTKDYEGPVIAPKVAAALEDALRE--EDEIQVDASGF----------HASLGSSPGLSASAAGFSKKPKSGRPKTGKKVSTPTSAHSPL---------SGSGSPLYPQSRGLVPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O55165-1", "uniprot_id": "KIF3C_RAT", "id": "O55165-1", "name": "Kinesin-like protein KIF3C", "aln": "MASKTK---------ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAP-GELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTPGGPATQSTAGGGGGGGGTSGSGSSGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKKGMLGKRPRRKSSRRKKAVSAPAGYPEGAVIEAWVAEEEDDNNNNHRPPQPTLEAALEKN--MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLKREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLLRDEETMELRGTYSSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHEEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPL---VPAGVNNSQMKKRPTSAVGYKRPISQYARVAMAMGSHP--RYRAENIMFLELDVSPPAIFEME----FSHDQEQDPRVLHM--ERLMRLDSFLE----------RPSTS-----------KVRKSR-SWCQSPQRPPPPSTVHAS-----------MASAPLHPATVVDHD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35066-1", "uniprot_id": "KIF3C_MOUSE", "id": "O35066-1", "name": "Kinesin-like protein KIF3C", "aln": "MASKTK---------ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAP-GELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNAAGGPATQPTAGGGSGSGSASGSASSGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKKGMLGKRPRRKSSRRKKAVSAPAGYPEGSVIEAWVAEEEDDNNNNHHPPQPILEAALEKN--MENYLQDQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLLRDEETMELRGTYSSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHEEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWRFQPL---VPAGVNNSQMKKRPTSAVGYKRPISQYARVAMAMGSHP--RYRAENIMFLELDVSPPAIFEME----FSHDQEQDPRVLHM--ERLMRLDSFLE----------RPSTT-----------KVRKSR-SWCQSPQRMPPPSTAHAS-----------MTSVPLHPATVVDHD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14782-1", "uniprot_id": "KIF3C_HUMAN", "id": "O14782-1", "name": "Kinesin-like protein KIF3C", "aln": "MASKTK---------ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAP-GELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGG--SGGGAGGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKN--MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPL---VPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHP--RYRAENIMFLELDVSPPAVFEME----FSHDQEQDPRALHM--ERLMRLDSFLE----------RPSTS-----------KVRKSR-SWCQSPQR-PPPSTTHAS-----------LASASLRPATVADHE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46867-1", "uniprot_id": "KLP68_DROME", "id": "P46867-1", "name": "Kinesin-like protein Klp68D", "aln": "MSAKSRRPGTGSSQTPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGN-KEQRKVFTYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHINRTENFQFLVDVSYLEIYMEELRDLLKPN-SKHLEVRER-GSGVYVPNLHAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETN---TIKVGKLNLIDLAGSERQSKTG--------------------------ASAERLKEASKINLALSSLGNVISALAES-SPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKKQRVKKPK---------------KETVTKEMSD---------------------SLQVSTIEQPVEDDSDPEGAESESDKENEAEVAKSNEELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREIEIQQQLELQEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNELVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGDGKFSSKRPVSHPQRRRPTSEYALQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTPKVSASLQAVLAQAMQTGGDDIDIVDSHTNSLRSRLENIINANANGGAGPGAGVAVGSSIPNVRNIKSSRGLPSAASNLDSNRRPPTGRLPAKKPASAYPKARGLVNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : ..*.::**.****:. :*. .:: : : * * : * * *.**:*:.** .:.* **.*.. **:.*** **** :***********:**:* : * *:**.:*::*: **.*::* *:** .****** **:****. : ::**::*. :***: :* :: *.*.:: :**::**: *:** *:*** ********:*.:* .: : *:******:******** *:* : .** ***:****:**:*****:**. . *.*:******************::*:*:*.:**:.:. :*:*:***:*.***.*:*:* ****:*: *:*:**** *** : : . : :: : .. * . :* : .. :*.. . * : :*.:*: . * ** :*.:*: **:*::* .*:* ** * ****:*:** *::*:: ::* *:*:: **:***::*.:**.* ::* ::: *::* :.:: : ::** :*** .:*** : ***:**:* * *.:: .: * *:: *:: .: . ***.* :** *::* . *:::***: **::. : : . . .:: : :*: ... .. :: : ..:: * : ", "identical_positions": 266, "similar_positions": 226, "identity": "31.18%" }, { "cls_id": "homologset.agr.FB:FBgn0004387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L5F9-1", "uniprot_id": "A0ABK0L5F9_RAT", "id": "A0ABK0L5F9-1", "name": "", "aln": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQETVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEALFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDAEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN----------PLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQT-LALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLIPLSGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSCENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETRRKETEIVQRQIRKQEESLKRRSFHIENKLKDLLAEKERFEEERLREQQGLEQQK-RQEEDSFFRIREELRRLQELNSHEQAEKGQPLQDLDWLHREQDAQSAKLQLEKRRLEEQEKEQVLRVAHLEEQLRKRQDTAPLLCPGEAQQAQEERRELEGIRGALLQAKEIRAGGDHTFRGELERAQQYFLEFKRRQLVKLATLEKDLVQQKDRLSKEVQEEKEALEHVKCEAGEEPSLLATDNC---NILCGPQDLDKIKTAESRLQSKEHQLQDLLQNHLPALLEEKQRVLEILDCGVLGLDNILYHVEKEMEEKEEQITQYQANASQLQQLQATVQFTANVARQEEKVRRKEKEILESQEKQQREALEQAVAKLEQRHSALKRRSTLDLEIQEQRQKLGSLHSS--EWPGLQASLEANGERLQMDPARIEHEIHELKQKICEVDGVQRPHHGTLEGKAALSSLPPSAENSHLAPLMDARISAYIEEEVQRRLHDLHRVISDASHAPAELK-SNEELHNGATQRKLKYELCQDLLGVLMSGSEAAAYTNHPLLHQDLVQLSLDLKAEIPVLALANGVQLSSNFQTTLVDMVYFLHGNMEASVPSLAEVQLLLYTTVRLESEAGCALCRSFILLN-THVALLR-EDHVFYPRTGSLITLPPHGRFDVITCQALSEFRCVIVPEKDNVSKVELVFLRKHGLPLNRGSGLSEQSQVASSSQMVTPLCLEDGQNQTLDIWKLTFNSQDEALWLISYLTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVY7-1", "uniprot_id": "KI16B_MOUSE", "id": "B1AVY7-1", "name": "Kinesin-like protein KIF16B", "aln": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEALFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDAEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN----------PLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQT-LALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLIPLRGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSCENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETRRKETEIVQRQIRKQEESLKRRSFHIENKLKDLLAEKERFEEERLREQQGLEQQR-RQEEESLFRIREELRKLQELNSHEQAEKVQIFQELDRLHQEQNAQSAKLRLEKRRLEEEEKEQVQRVAHLEEQLRKRQDTAPLLCPGEAQRAQEEKRELESIREALLQAKEMRAGGDHTCRDELERAQQYFLEFKRRQLVKLASLEKDLVQQKDLLSKEVQEEKVALEHVKCDAGGDPSFLATDDG---NILGGPPDLDKIKTAETRLQSREHQLQDLLQNHLPALLEEKQRVLDALDSGVLGLDTTLCQVEKEVGEKEEQIAQYQANASQLQQLRATFEFTANVARQEEKVRRKEKEILESQEKQQREALEQAVAKLEQRRSALQRCSTLDLEIQEQRQKLGSLHTS--EWSGWQASLETDGEALEMDPARLEHEIHQLKQKICEVDGVQRPHHGILEGQAVLSSLPPSGGNSHLAPLMDARISAYIEEEVQRRLHDLHRAIGDANHTPADVMKSNEELHNGTTQRKLKYER-------MYSRS----------LGTNRDDLKDPIKISIPRYVLCGQGKDE--------------HFEFEVKISVLDETWTVFRRYSRFR-----EMHKTLKLKY-AELAALEFPPKKLFGNKDERVVAERRTHLEKY----LREFFSVMLQ-----SETSPLHINKVGLTLSKHT-ICEFSPFFKKG-------------------VFDYSSHGTG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L93-1", "uniprot_id": "KI16B_HUMAN", "id": "Q96L93-1", "name": "Kinesin-like protein KIF16B", "aln": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN----------TLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQT-LALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDG-EELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYER-------MVSRS----------LGANPDDLKDPIKISIPRYVLCGQGKDA--------------HFEFEVKITVLDETWTVFRRYSRFR-----EMHKTLKLKY-AELAALEFPPKKLFGNKDERVIAERRSHLEKY----LRDFFSVMLQ-----SATSPLHINKVGLTLSKHT-ICEFSPFFKKG-------------------VFDYSSHGTG----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VB25-1", "uniprot_id": "KL98A_DROME", "id": "Q9VB25-1", "name": "Kinesin-like protein Klp98A", "aln": "MSSLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQS--IRDAGRDNHHDFTFDYSYWSFDAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEELFARMRVGQESGTG-YRTHASYLEIYNERVKDLLAAQSTG-HGLRVREHRSLGPYVENLSQHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSETVSKIHLVDLAGSERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLIRELREEINKLKSMLAG----DIHSLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQSILQEQKSLGLRKSGVGVVLDSEMPHLIGIHNDVT-TGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKDLSRSQLDMSRLSLITSSK--ENLLTCSIYSDEDGASPYKRPERQYYP-QRPMSRDDPELQDENRKILDTIENALKQLNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLLNCREQELIARKDMLLWEK----------------------NNEKVQIDIVCRQISAFQTQLDSK----KRDFSEYVAKELQELQDCGKLDEMGMKIEEGTPLN----DELLLQVSDSLDLFAAQFIKDTVRRNNEEIRKLDEQIAEKERILNASTTKIAKVDETMLEIQAQLERLRLERAESEAESQAMRAKKQNMKLQLGNKSMSTSTSTNEADDVSKSDTYET-CDTFHTAQSNLSLVSSPTITEGQQSPLSNCSCD---------------AEDEAEDTRKDDLSGSSEETSRTCTAGPSSGSGSGSVGIGGSGSAPSCTPSSQAIMSDSGVCLDSRNQAILQNGHLNNYKQAVRTSDEDTGSCSSCELGRHSDVARPYCPLHS-LRRKIAAQKALIMKNLETDLNKAQLDEHIADLQDLQRRYIQMEQEMLQSVQDLEAHAQCCADERSGMERQYELASSIMRSSVMSPTSMEESTSQIYSPSMTRSCP-----------------------SMREFPEGEHFITIPSFVMRGAGKQT--------------HYEYEVRIALPDGKLNILRRYSRFR-----ELHLCMKHCYGAKISALPFPRRELFASNSEPVAKHRRRLLELY----LRRLFVVCSK-----IPQCPIYEGPGGTGLTRAS-LVQLSSFFKKG-------------------LFENGKHGTG----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:********:* ** *::*::*::**:.** : : :: . *:**:. : **:*:*::* *::.*.:.:** *:. **.***..*:*****************::****...:.******** **:*:. . . . :**..**********:*** :*: ..****** . *****:**:* *.::.:::* : ** :****:*.***.**********.*.** * :**.*****************:****** *****.:*********.******: : .. * ..*: :::*****:*******************::**** **.********************:***:********* ** :**::** : . .:*.: .*:::**: : **:***:**: :*.**:**. *.***.*:*******:******.:*: **: ** ****:* :* :**.. *** * * .:.::** : **.*** * :** **. * :..::.** :*******:****:* ******:. . . *. **: ** *** : :*. . :* * : :* : .: * *..:: *: ::: :: . * :: * :.: ..*... :::*:: * * : *:* : .:: : :: .:*:.: :::. :: : : : . : . :* ::: .:*:* : :: * : : .*: : ::: . * . : * : ::: . ::.*: :: * : * * *.: : ::.. * ... . *..* .. * : . . * *:: * :* :. . . *.* : :: : :.. :: * .. . . .* . * ..: :. : . *: *..*: : . *. : * . . : * ::.: *. * : * * *.* : . : . . . :. * .: * . * : : :. :. .. :.. . *: . . .:. . . ** .: . : * : *. :. :: *:. : : :.:: * : :: ... : : :: * : * :. * *.: : : : * . ... : ..:. . ", "identical_positions": 403, "similar_positions": 394, "identity": "28.68%" }, { "cls_id": "homologset.agr.FB:FBgn0004390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYJ2-1", "uniprot_id": "RASA3_RAT", "id": "Q9QYJ2-1", "name": "Ras GTPase-activating protein 3", "aln": "------------------------------MAVEEEG-LRVFQSVRIKIGEAKNLPSYPGPNKMRD------CYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRR-DSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDT-------------------------------------------------------------------GVVCHK-------------------------------LAARIFECQGLPIVNGQ-CDPYATVTLAGPFRSEA-KKTKVKKKTNNPQFDEVFYFEVTR-------PCSYSKKSHFDFEEED-----------VDKLEIRVDLWNASN-LKFGDEFLGELRIPLHVLR--YASSYEAWYFLQPR------------------DNGSKSVKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRD--KQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFSVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLG---SLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDP--------KSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKG-DQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAIGCTPCTGGLPANIQLD----IDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEY----------STFIIDDPQETYRTLKQVIAGVGTLEQEHAQYRRNKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60790-1", "uniprot_id": "RASA3_MOUSE", "id": "Q60790-1", "name": "Ras GTPase-activating protein 3", "aln": "------------------------------MAVEEEG-LRVFQSVRIKIGEAKNLPSYPGPNKMRD------CYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRR-DSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDT-------------------------------------------------------------------GVVCHK-------------------------------LAARIFECQGLPIVNGQ-CDPYATVTLAGPFRSEA-KKTKVKKKTNNPQFDEVFYFEVTR-------PCSYSKKSHFDFEEED-----------VDKLEIRVDLWNASN-LKFGDEFLGELRLPLKILR--HSSSYEAWYFLQPR------------------DNGNKSLKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRD--KQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLG---SLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDP--------KSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKG-DQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLD----IDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEY----------STFVIDDPQETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14644-1", "uniprot_id": "RASA3_HUMAN", "id": "Q14644-1", "name": "Ras GTPase-activating protein 3", "aln": "------------------------------MAVEDEG-LRVFQSVKIKIGEAKNLPSYPGPSKMRD------CYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRR-DSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDT-------------------------------------------------------------------GVVCHK-------------------------------LATRIVECQGLPIVNGQ-CDPYATVTLAGPFRSEA-KKTKVKRKTNNPQFDEVFYFEVTR-------PCSYSKKSHFDFEEED-----------VDKLEIRVDLWNASN-LKFGDEFLGELRIPLKVLR--QSSSYEAWYFLQPR------------------DNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCRE--KQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLG---SLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDP--------KSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKG-DQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLD----IDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEY----------STFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F916-1", "uniprot_id": "E7F916_DANRE", "id": "E7F916-1", "name": "Ras GTPase-activating protein 2", "aln": "------------------------------MAVEEEG-LRVFQSVKIKIGEAKNIPPYPGPNKMRD------CYCTVNLDQEEVFRTKTIEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRR-DSSIGKVAVKKEDLQKYHGKDHWFPLQPVCADSEVQGKVHLELRLSELITDS-------------------------------------------------------------------GGLCHK-------------------------------LATRVLECQDLPIVNGQ-CDPYAAVSLLGPSRSEA-KKTKVKRKNNNPQFDEIFFFEVTK-------PLSFTKR-QFDVEEDD-----------VDKLALKVDLWNASN-LKFGDEFLGEVRVPLKVLG--QAGVHDAWYFLQPR------------------DNGHKSVKADELGSLRLNIVYTEDHVFPTEHYNPLRDLLLQSAHVQPVSASAAHILGEVCRE--KQEAAVPLVRLFLHYGKIVPFLSAIAHAEISRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLRVTLKPIIDEICSDHKPCEIDPVKLKESENLDTNRENLRQYVDRIFSVITSSGVSCPTVMCDIFFSLRESAASRFQVDADVRYTAVSSFIFLRFFAPAILSPNLFHLRPHHPDPCTSRTLTLISKTIQTLG---SLAKSKSANFKESYMAAFYDYFNEQKYADAVKNFLDLISSSARWDQ--------KSIETPIMLKEGFMIKRAQGRNRFGLKNFKKRWFRLTNHEFTYHKTKG-EGALCSIPIENILAVERLEEESFKMKNMFQVIQPERALYIQANNCVEARDWIDILTKVSQCNRKRLSTFHPSAFLNGHWLCCKLSADTAPGCTPCTGGLPANIQLD----VDGDRETERIYSLYSTYMSKLVKMQEACGSKSVYDGPEQEEY----------STFVIDDPQETYKTLRLVISAVQTLEQQHTQYKRDKFRKTKYGSQEHPIGDQSFQCYIRQQSESSTYSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63713-1", "uniprot_id": "RASA2_RAT", "id": "Q63713-1", "name": "Ras GTPase-activating protein 2", "aln": "-----MAAAAPAAAALT-EAPAVPGTAEPETGDEDSREVRVLQSLRGRIYEAKNLLPYLGPNKMRD------CFCTINLDQEEVYRTQVVEKSLSPYFSEEFYFEIPRTFQYLSFYVYDKNVLQR-DLRIGKVAIKKEDLCSHSGKETWFSLQPIDSNSEVQGKVHLELKLNELITEN-------------------------------------------------------------------GTVCQQ-------------------------------LVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQ-KKTKVKKKTSNPQFNEVFYFEVTR-------SSSYTRKSQFQVEEED-----------IEKLEIRIDLWNNEN-LVQ-DVFLGEIKVPVNVLR--NDSSHQAWYLLQPR------------------DNGNKSSKPDDLGSLLLTLCYTEDYVLPSEYYGPLKALLLKSPDVQPVSASAAYILGEICRD--QKDAVLPLVRLLLHHNKLVPFITAVADLDLKDTQDANAIFRGNSLATQCLTEMMKIVGGHYLKVTLKPVLDEICESSKSCEIDPVKLKEGDNVESNKENLYYYVDKVFSAIVGSSVSCPTVMCDIFYSLRQMAAKRFPNNPHVQYSAVSSFVFLRFFAVAILSPHAFHLRPHYPDTQTVRTLTLISKTIQIIGNWGCQSRRK-SRFKKSVMCEFLKMFQEERYFTDVKKFLDEISSTETKES--------SGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSKELTYHKQQG-KDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKTLYIQANNCVEANEWIDMLCRVSRCNHNRLSSFHPSAYLNGNWLCCQETSEGTPGCKPCTAGIPADIQID----IDEDRETERIYSVFTLSLLKLQKMEEACGSIAVYQGPQKEPG---------YSKFTIEDSVATFKTIQQIKSTIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKIS---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58069-1", "uniprot_id": "RASA2_MOUSE", "id": "P58069-1", "name": "Ras GTPase-activating protein 2", "aln": "-----MAAAAPAAAASP-EAPAVSGSADPETGDEDSREVRVLQSLRGRIYEAKNLLPYLGPNKMRD------CFCTINLDQEEVYRTQVVEKSLSPYFSEEFYFEIPRTFQYLSFYVYDKNVLQR-DLRIGKVAIKKEDLCSHSGKETWFSLQPIDSNSEVQGKVHLELRLNELITEN-------------------------------------------------------------------GTVCQQ-------------------------------LVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQ-KKTKVKKKTSNPQFNEVFYFEVTR-------SSSYSRKSQFQVEEED-----------IEKLEIRIDLWNNEN-LVQ-DVFLGEIKVPVNVLR--SDSFHQAWYLLQPR------------------DNGNKSSKTDDLGSLLLTLCYTEDCVLPSEYYGPLKTLLLKSPDVQPVSASAAYILGEICQD--QKDAVLPLVRLLLHHNKLVPFITAVAELDLKDTPDANAIFRGNSLATQCLTEMMKIVGGHYLKVTLKPVLDEICESSKSCEIDPVKLKEGDNVENNKENLYYYVDKVFNTIVGSSVSCPTVMCDIFYSLRQMAAKKFPNHPHVQYSAVSSFVFLRFFAVAILSPHAFHLRPHYPDTQTVRTLTLISKTIQIIGNWGCQSRKK-SRFKKSVMCEFLKMFQEERYFTDVKKFLDEISSTETKES--------SGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHRQQG-KDAIYTIPVKNILAVEKLEEGSFNKKNMFQVIHTEKTLYIQANNCVEANEWIDVLCRVSRCNHNRLSSFHPSAYLNGNWLCCQETSESTPGCKPCTAGIPADIQID----IDEDRETERIYSIFTLSLLKLQKMEETCGSIAVYQGPQKEPG---------YSKFTIEDSVATFKTIQQIKSTIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKIS---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15283-1", "uniprot_id": "RASA2_HUMAN", "id": "Q15283-1", "name": "Ras GTPase-activating protein 2", "aln": "-----MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMRD------CFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQR-DLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLNELITEN-------------------------------------------------------------------GTVCQQ-------------------------------LVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQ-KKTKVKKKTSNPQFNEIFYFEVTR-------SSSYTRKSQFQVEEED-----------IEKLEIRIDLWNNGN-LVQ-DVFLGEIKVPVNVLR--TDSSHQAWYLLQPR------------------DNGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICRD--KNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSK-SSFKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKES--------SGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHKQPGSKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKPLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVYLNGNWLCCQETGENTLGCKPCTAGVPADIQID----IDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDD--------YSNFVIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2T9-1", "uniprot_id": "A0A8M6Z2T9_DANRE", "id": "A0A8M6Z2T9-1", "name": "", "aln": "------------------------------MAEDDDTKIRILQSLRGKICEAKHLGPNSGPNRLRDLC----TFCTISLDQEEVYRTKVFEKSVSPFYSEDFYFEIPRPFQCLSFYVYAKSMFQIRDLPVGKVAIRKEDLYKYCGKENWFQLQPVDPHSEVQGKVHLEMKLNELITEN-------------------------------------------------------------------GSVCQQ-------------------------------LVVQIIACQGLPLISGQNCDPYATVTLVGPTRSDQ-KKTKVKKKTSDPQFDETFHFEVTR-------SSSYKGRSQFHVEEED-----------IEKLEIKVELWNNGN-LAQ-DVFLGETRVSVKILR--NDHVHRAWYLLQPK------------------GNGTKS-KPDDLGSLRLKVTYTEDNVLPSACYTALRNLMLKSPDVKPISASAAHVLGDICREGVGYDALLPVVRLLLHHNRLLPFLTAVAALELENTQEANTIFRGNSLATRCIDDMMKIVGRSYLTVTLKPVLNEIFESIKTCEIDPVKLKEGDNVEVNKENLQGYVQKVFTSITQSSSSCPPLMCDVFRSLRQLASKRFPADPHVQYSAVSSFIFLRFFAVAVLSPHTFQLRSHHPDPEISRTLTLISKTIQSLGSWGSLSKNKLSSFKETFMCDFFKLFQEDECIEKVKKFLDEISSNVSKES--------SGVEDSFVLKEGEIHKRAQGKKRIGKKNFKKRWLRVTNQELSYHKQKG-KEALCVIPVKHILGIEKLEESAFNRKNMFQVIHSEKPLYVQASNCVETNSWIEVLSQVSRCNPGRLSTFHLSAYVGGSWLCCKEPNESAPGCKPCTATVLANIQLD----IDCDRETERIFSFFSTYRSRLQKMEDVCAGMSVYLGQQEECS-----------AFTIQDPKETFRTIKELG---EVLDELQSHHDSKGALTDEPGTIENPIVGKTA---------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48423-1", "uniprot_id": "GAP1_DROME", "id": "P48423-1", "name": "GTPase-activating protein", "aln": "MLLKKKRYMFDERDDNNINSPVAVEPSSNNNKMADTREVRIEEQLKVKIGEAKNLSSRNAANTSCSTQGTRDVYCTIALDQEEICRTPTIERTLTPFFGEEHQFKIPRRFRYLTIYLWDRDMKQD--KPIGKIAIKREELHMYNHKDHWFSLRPVDQDSEVQGMVNVEVAFTEAQQTQSLSEGIDLGQHTLRHHQNLPHHSHQQRAHLNDYKENSELSNIQRASAAAASSSSAAMTLKTRAAGLFGHVHHPPSQTQHFPIINTTSTSSDQLSNWKSHGRFVGVTIKVPACVDLAKKQGT-CDPFVVCTAHYSNKHQVTRRTKQRKKTVDPEFDEAMYFDLHIDADAGSTNTTGSNKSAGSLESSANKGYSIYPVGGADLVEIVVSVWHDAHGAMSDKVFLGEVRLPMLNKQEQQAVNPSAWYYLQPRSMTHSSRSLNATPRSCATPPGTRLSVDSTIGSLRLNLNYTADHVFPLATYDDLMNLLLESVDQRPITVSAVSILGELVSG--KTEVAQPLVRLFTHTERIAPIIKALADHEISHLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHQTLRPVLSQIVAEKKPCEIDPSKIKDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDLRECAGEHFPSNREVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQTSRTLTLISKTIQSLGN-LVSSRSSQQTCKEEFTVELYKKFCTEQHVDAVKHFLEVISTPSHASSSVHPAAAAATPLEPVLLKEGLMTKYPTSRKRFG-RQFKQRHFRLTTHSLSYAKSKG-KQPICDIPLQEIASVEQLKDKSFKMQNCFKIVHNDRSLIVQTTNCVEEREWFDLLHKICLMNSIRMQYFHPSAFVSGFYSCCGRSDENSPGCKKVLDKTMDYFQMDLVTALDPALDLQRIHTLIMSNMSVLESLLDPLTYHQSLSQTQHQQHNPLVPLATDLQKHSPQAFAEFKRTIEKLREKAYAIDRDHRDYKQGITRQLKYGSRQAPIGDDNYWHMMRAAGQLNQQHHQQQQHQQQQQQQQQQQLQQFQPQPVLPQMQNVRAYPYQPATSNMNAYCLHNMQYQQQRLPFHQQQQQHHQQLQQQQSQFQPLRSHQLQRHNNNLNNNNCGNGSSSSPSSTTSSVVAAPPSTTSSSQPAPPIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: :.:: :* ***:: . .. . :**: *****: ** .*::: *::.*:. :*** *: *::*:: :.: : :**:*:::*:* : :: ** *: : .***** *::*: :.* * : : :. :: * .*. .* ***:.. : . : : ::** ::*. :*:*:* :.*:: : . : .*.. : : : :.:*: : . **** ::.: *** ***: * : . :*** *.: ** * *:. * * *:*:* . .*::.**. :*.:: :. *:***: * :: *: .*:* ::. :..:*****:*.:: : : *:: * ** **:* :.:* . *.***** *:*: . :: * ..* **:::* *. *. ** ::*::* .**: * .:* . .*:*:.**.*:****** *::.*: *.* .. *. *********:* :* :: . *: : . * : **:**: **: . .. **** : * . .:.*:* ::**:* : :*.:.::* : * . .: **::.* .:*:*:: :*. :* *:::: ::.* :*:.**** ..*:::* ::. * *: :* *.::.* : ** . : : **. :*:* :* : :**.:. * .: : :.: . : :*:. : ::. : .: . *: : ** .. ", "identical_positions": 211, "similar_positions": 291, "identity": "18.02%" }, { "cls_id": "homologset.agr.FB:FBgn0004391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M801-1", "uniprot_id": "F1M801_RAT", "id": "F1M801-1", "name": "Anaphase-promoting complex subunit 1", "aln": "MSNFSEERATMIAAG---DLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVG---------------------------------SLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQ-----ALAVYKAFTVDSTVQQALWCDFIISQ----DKSEKIYKSHELEKCICILQSSCMNMHSI-DGKDYIASLPFQVANVWATKYGLLFERSSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEETAVLKFPEQAGTLQNAATSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSASSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNLSSHNQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLP-NMREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIDTMLVLEGNGNLVLYTGVVRVGKVFIP------GLPAPSLTMSNMMPRPSTPLDGVSTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIH-------------------SVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAVQVLVKWYNVHSAPGGP--SCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDDDWEYLLNSEYHHNVES----------HLLNKSLCLNALEVTKTKDEDFPQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLEPYLDHYYRDYPTLVKTTGQVCTIDQGQMGFMHHPSFFTSEPPSIYQWVSSCLKGEG-TPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETSQYLSKVTLTPQKPQAEQEENRFTFRQSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPR-----------------GKSVLSSDVASGAEAEEEDDGMNDLNHEVMS-LIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAP-ASQIDSAWIVYNKPK-HAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSD-------LNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLD--FVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE---NSIS--LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMNYLSAPNASVTGP----YNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTG---GEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGQKQEILD--LFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSNTSDLWQIKLILEFFSSRSHQERQQTYPKRGLFINSEFLPVVKCTVDSTLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPLGLEGSTSFAELLFRFRHLKMPVRALLRLAPVLLGNPQPMVM--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53995-1", "uniprot_id": "APC1_MOUSE", "id": "P53995-1", "name": "Anaphase-promoting complex subunit 1", "aln": "MSNFSEERATMIAAG---DLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVG---------------------------------SLQEVTIHEKQKESWQLRKGVSEIGDAADYDEELYVAGNMVIWSKGSKSQ-----ALAVYKAFTVDSTVQQALWCDFIISQ----DKSEKIYKSHELEKCICILQSSCMNMHSI-DGKDYIASLPFQVANVWATKYGLLFERCSSSHEVPPSLPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDPAVKIVFLNIDPSIVMTYDAVQNVHSVWTLRRVKPEEENAVLKFPEQAGTLQNATTSSSLTAHLRSLSKGESPVASPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGAQRFNLSSHSQSPKRHSISHSPSGSFNDSFLAPETEPIVPELCIDHLWTETLP-NIREKNSQASKVFITTDLCGQKFLCFLVEAQLQLRCVKFQESNDKTQLIFGSVTNIHAKDAAPVEKIHTMLVLEGNGNLVLYTGVVRVGKVFIP------GLPAPSLTMSNMMPRPSTPLDGVGTPKPLSKLLGSMDEVVLLSPVPELRDSSKLNDSLYNEDCTFQQLGTYIH-------------------SVRDPVHNRVTLELSNGSMVRITIPEVATSELVQTCLQAIKFILPKEVAIQVLVKWYNVHSAPGGP--SCHSEWSLFVICLLNMMGYNTDRLAWTRSFDFEGSLSPVIAPKKARPSDTGSDEDWEYLLNSEYHRNVES----------HLLNKSLCLTALEVSNAKDEDFSQNLSLDSSTLLFAHIPAIFFVLHLVYEELKLNTLMGEGICSLIDLLVQLARDLKLDSYLDHYYRDSPTLVKTTGQVCTIDQGQMGFMHHPPFFTSEPPSIYQWVSSCLKGEG-MPPYPYLPGICERSRLVVLSIALYTLGDESCVSDETCQYLSKVTSTPQKPQAEQEENRFTFRHSASVSVLAERLVVWMASVGFTLRDLETLPFGIALPIRDAIYHCREQPDSDWSEAVCLLIGRQDLSKQACEGNLPR-----------------GKSVLSSEVSSGTEAEEEDDGMNDLNHEVMS-LIWSEDLRVQDVRRLLQSAQPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPVPKLNLTGRAPPRNTTVDLNSGNIDVPPNMASWASFHNGVAAGLKIAP-ASQIDSAWIVYNKPK-HAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHVPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSD-------LNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLD--FVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE---NSIS--LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFSCLHKFAKDFMNYLSAPNASVTGP----YNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTG---GEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALIEVTYKGTQWYEQTKEELMAPTLLPELHLLKQMKVKGPRYWELLIDLSKGEQHLRSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISSFTSDPALLSFAEYFCKPTVSMGPKQEILD--LFSSILYECVAQETPEMLPAYIAMDQALRSLKKRDMSDTSDLWQIKLILEFFSSRSHQDRQHTYPKRGLFINSEFLPVVKCTVDATLDQWLQAGGDVCVHAYLSGQPVEKSQLNMLACFLVYHSVPAPRHLPPMGLEGSTSFAELLYRFRHLKMPVRALLRLAPVLLGNPQPMVM--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1A4-1", "uniprot_id": "APC1_HUMAN", "id": "Q9H1A4-1", "name": "Anaphase-promoting complex subunit 1", "aln": "MSNFYEERTTMIAAR---DLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVG---------------------------------SLQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQ-----ALAVYKAFTVDSPVQQALWCDFIISQ----DKSEKAYSSNEVEKCICILQSSCINMHSI-EGKDYIASLPFQVANVWPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETIT-NIREKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIP------GLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIH-------------------SIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGP--SYHSEWNLFVTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVES----------HLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEG-MPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQACEGNLPK-----------------GKSVLSSDVPSGTETEEEDDGMNDMNHEVMS-LIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAP-ASQIDSAWIVYNKPK-HAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSD-------LNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLD--FVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE---NSIS--LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGP----HNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTG---GEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMGQKQEILD--LFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXV3-1", "uniprot_id": "Q9VXV3_DROME", "id": "Q9VXV3-1", "name": "", "aln": "MIAVAEPPLEFVPRGRQTSAEHPGPHDQPMARHQLPTTEHLLLQRLQNVNISSAGEDCPSGGQESWTVRELYDDYEASEERAALRRKLTERTKRCGLQATSLPNRLLNPPLVRRVEPMCDYMVNNEEELYVNRNTVVWTQGVNDDDDTDNGVYRRMCFTTDTPVRFACFLNRSFVRGRLAQLKAAVHPDDDHLTAICVMDQDALRVYCS-NGEDFLANLDFPVSQLWQTKYGLLLEKDSSNALISHMS--IPMPRLFSMSHPLHEACPVVLKT----ATGSTGYMTEPEYTVVFTTEESDLVMLYDAKFFKHFVARLRKVTPEEINYVSQQMELGQTLMGPRSMAGNSFSSTKQTGATPKATN--LSFAARNINTTTTGMGNQFGLSQSQSFSGVLGQSNRASLGTPLSQLQSSISQQSMSVKDMRKLTHVKP------------AKPIEPELCMEHIWTENIYGTQREFCEMATRAFIHTDLVGQTFLCYLLARSCRLQLVRLTGYGRGEVQLSTHASTLAAKDAVGLKRMHMIAVLDPSGSLLLYTGTVLISKVHITPFLAPTSIPTPLVTPMTAAPSPSASPAPSHVKTPMAAAGPASGIPSGSSSFVEVRRSSLLPTKAPGDVAAFEEELHMLSPIQPQPVSYTQRQAHNVCKSLRDPAGNRLTLVYATGRMLRIALPFLNDTRLLTRCVATLRQVLSPTQFLDFVIRWYSDRNPPGSRNYSIEQEWLLFRSTLLALMGLTAAPDVDAGENYARCATPPLHTQFGGGATATESSDGSSCSSNSTLGGQDEPKKRRIYNDCDDFTDDDWEFLLLQTTLAPCGADGHSYSVNIGALLFRMIPAIFFSLHLLYEDLKLDADFYGALPYLATFLHQLAIDMQLESYVLHYILDFPELSNRTGKLSLLGAEHGAMMLHQELLRVPAPSVFAQLEHIIVGEEEVMPYTFLECVNERSRILLQLVSLVTHG------HERLNYWWQLLEIPGAVQAN--FTRRSKRNITADAPRSHQMLQLLLAMRLTRRDIERFPAAVHLIVAEALEEARLSPPMGCSMATYELILRPELAAHAQLPFLETSTGQPHCGRVYKEDSLSARCPPTGGSETDSPAQLRRDDMDNMDTKLLR-LRFPDDMRVDEVRRLLNSSEPVVIEVQQAPGTSDHEFIEEQEKQLFALCSRTMTLPVGRGMFTLRTMLPRPSESLTMPKLCLLGKEPLKGTTIEMQ--QIEFPANMQMWPSFHNGVATGLKISPQAQDIDSNWIVYNKPKTHSHNALEHAGFLMALGLNGHLKTLSFMSVYKYLVKCDEMTNVGLLLGISAAHRGTMDTKTTKLLSVHLEALLPATAMELDIPQSTQVAAIMGVGLLYQGSAKRHIAEVLLQEIGRPPGPEMENSIERESYAMTAGLSLGLVTLGQGESPAGLRD-------LQLPDTLHYYMVGGVKRPIGGSQKEKYRLASFQVREGDTVNIDVTAPGATLALGLMFFNSGNAAIAEWMQPPDSRYLLD--MVRPDFLLLRTISRGLILWQDVRPDNAWFQAQFPRALRA---HLKLPFYENEYAPEDYDVDYEAISQAYCNIMAGAAFCIGLKYAGTENLVAFATLRSVIKDFLRFPSRPMGECAGR----TTVESCLMVLLISISLVFAGSGNCEILRIIRFLRSRVGPQYPHITYGSHMAIHMSLGLLFLGAGRFTISQTPESIAALVCAFFPKFPIHSNDNRYHLQALRHLYVLAVEPRLFLPRDIDTNKLCLANISVLEVG---ATELRRLPIAPCILPVLSTLQQVVVDDENYWPVCFERSRNWDQLEKALEMSAPIDIKKRTGCLSHLEDPDRLKSMLAQTLTMEQSICWQIDMNDLQQFASERMVKQFLSRCLDTKGTDLSPPELMKRHQVMLLFYNAVVKDRMHFLPVYLTLYDHVT----KSMPNNIDVWQMKLIDAYLS-RSQESEHPLISVELIQMMQELFKQEMEDSTRELCLPLREFLSRRRLDPSYVTTVSGPDLQRAFCVINYYNLLPNMLNGVDLSTGTVNYMRLLYEFRRLNLGAHTIFGLMKILQSLATEVVTLDEAALLAYTMGDQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53886-1", "uniprot_id": "APC1_YEAST", "id": "P53886-1", "name": "Anaphase-promoting complex subunit 1", "aln": "------------------------------MTSKPSTRNDYLPRETHNGEYTGDS----------------------------------------------------PEWQLQINITNKIGGINGDIWLSRDGRSVKWCIEDQCLR----------QFTYNQKIIKAGYIDFEKTP-----------------DCFVVVLSDIAHVYMLKNGGSTTVCFPFQIGNAFWYANGVILERETSASFMDGGY--DLKPIEFDLKHKYITLTDPMAPFGLISITNTFKGGINSASGNKTDILQDFQLVLFPSDKDKCIAVFLDRNSKVLRFYYSRILSSDQSRKGELTISSTKKTGLDAAGNSQKSGGISKDLRKFSHLTRRSTSINSNSHDFNAAERVLSGNVGNASGRTDIFALPSSCSRRSLSATLDRMGNNIAP------------TNRAAPSGFFDSSSANTAT------HSNITPVSQPMQQQQQEYLNQTATSSKDIVLTEISSLKLPDDIIFTSRR----LSSILSKLKFLSLRFERREGLLIFHEPTHFCKIWLIDLLP-DVLDSIPFKIYGNSPQNMIRLENLKLKEPSRIQAMYIHELLESCLILVSEG----QNKEEYKACLYDPFVKITS--------------------PSKNISEELTKQNSLPSLQKLFP--YPETSFTKLCFEAVKYITSPAFNISFIFLWQSAYS------------------ILLSRANDDVVGGLKMEHDAFSLVLSLLILPIPSSSAQEYQEYKEIYERDLFQHLKQDS-----------------------------------------EITSSVLPRIVIGLHLIREEYSLNVLCRNEHALLGQFLRFATAAMGWPDLWQSYY--VPKMDSESKTFLHPREQNSTFFHPLDEPPSITKSLYSITENSSIPLCPFISFSRLVATDTQVELRITPRSFKILGLYELVHSPNFLPDYVLGILSSFKVDKDELQTYPLGILVPLQNILKILEDKLSEVRDNLELLDRADLQRCSAIINSIRSDSKEVLKRGQRDSYMLCKVPLAKNRSSLSKKPSD----IYSILSEIVKSASQVPLDGSAMRMSNIQDDEDIDEGRSLKLNAGLIFSEDKRFTHVVSLLAYYRPTKTQFFTT-KTEYAQILAQKKYFAKIMALRTCTNGVGWGAVAYATEKPISTQKWVIQPLNLISVFP--DDTKITVKAPEDIAHDIVEWGQFHAGVSSGLRISKKATGITGSWIAFNKPK---ELDAYHGGFLLGLGLNGHLKNLEEWHIYNYLSPRNTHISIGLLLGMSSSMKGSMDSKLIKVISVHLVAFLPSGSSDLNIDLKLQTAGIIGMGMLYLNSRHKRMSDSIFAQLVSLLNVNDEMVAD-EEYRLAAGISLGLINLGAGQTKLRKWDSSLLGLGDDLPEDVYDSSDVEQNVMYEDLTTKLLEIVTSTYDVENDWIPENSQIGAVIAIMFLFLKSNNFGISNMLKVDLKEILKANINTRPELLMYREWASNMILWEFIGDDLSFIMKDVDIGVKFSELN--------------------TDLLPIYYTMAGRILAMGIRFASTGNLKIRNILLSLVDKFLPLYQYPGKQNLDFRLTISVINVLTNVIVVSLSMVMCASGDLEVLRRVKYLHEVASGPYSDLFQEIPSSKSDVSGVTQVTSNTNTPGNSDRERVDETAASLDDERSSNGSD-------------ISDPTAYLEDKKDIDDHYGKFISTNLALGFLFLGSGQYALNTSTLESIAFLSMSVLP---TYTTPHPLQELKHFWSMAVEPRCLVIKDISTGDAVNN---VPIELVVEEDVEKEEVIREISTPCLLPDFSKIKSIRVKMHGYFPLEVNFTKDYSASDFFSGGTIIYIQRKSESVFENKASFRNVEDIHVALKRKAAESKNYSRLNLKNEQGNTTSSQLVESLGIQDLTMVELDTLLSAGNNTALTDSESYNLG--------LLCSDKNSGDILDCQLELWYKSFGPHDE-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : : . . :: . : : * . * * : ** : : * : : .: :: .. .:: :* . . : * :.: : *:::*: :* : * *.: * : :. : : :: : : . * : . : . : . : :. . . : . . : : . . . . : .. .: . . . * . . * * :: *. :: ::. . : . : * :* . : ..: : .: : :: .*::: . . *: : : : .. * * . . . . . . :: . :.:* : : :: : : *. ::: : . :..:. * . . *: . . . : . .: .. : : :. : :* *.: ***: *: .*:. * :* : : * * : : . : :: . *:: . .:. * : .: : :: * : . : . .. . : : : . . :: : ::: . * :: .: . : : * :. . :: * :.:* *. .* ** .*. :. . ::: ::: :. ** : ** * .: : * .:: : * * . * . * :.. :: * .** **::**:*: * * . **.:**** . :.***:.*******..* ::.** . .:*****:*:: *:** . :::*:*: *:**. : :*:: . *.*.::*:*::* .: ::: :: :: :: . : * : *.* ::**::**:: ** *.. * ::*: :: . . : . : : : : **.:*: ::::::.* .*:: :: . * .:*::*: * : :***: : : :. :. :: : : . :** :.:*:::*.: ** * .. ..*: . * . . :: *:::*:::*:..**: ::*: ::*: .. .: : *: : .. : . : . . .* . . .: :* : . * : :.. . : . * : *. : : .. . :. : . :* : :: : : .: : *:. : . . . ::* .: . : : : :. .:. : :::* . * : : : : . . :: : * .. . ", "identical_positions": 164, "similar_positions": 495, "identity": "7.86%" }, { "cls_id": "homologset.agr.FB:FBgn0004394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09086-1", "uniprot_id": "PO2F2_HUMAN", "id": "P09086-1", "name": "POU domain, class 2, transcription factor 2", "aln": "----MVHS-SMGAP-------------------------------------------------------EIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAAP-----------------------LPPQPAQPHLPQAQLMLTGSQLAG-----------------------------------------------------------------------------------------------------DIQQLLQLQQLVLVPG----HHLQPPAQFLLP------------QAQQSQPGLLPTPNLF-QLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLSHPQPPKCLEPPS-------------HPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AETMSVDSSLPSP----------------------------NQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLA-NQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRT---------------------AGGGGGGGGAAPPLNSIPSVTPPPPA-----TTNSTNPSPQGS------HSAIGLSGLNPSTG-----------PGLWWN---------------------------------PAPYQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LNT5-1", "uniprot_id": "A0ABK0LNT5_RAT", "id": "A0ABK0LNT5-1", "name": "POU domain protein", "aln": "----MVHS-SMGAP-------------------------------------------------------EIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAPAAP-----------------------PPPQPAQPHLPQAQLMLTGSQLAGLSALIPAQQQLLLQ--QAQAQLLAAAVQQSNAAAANAAAAAAAASTSSSTSSASSSTSQTPASSGGGDLPPSQPTSQPPGTPQLTLSQPIQLTA------QDIQQLLQLQQLVLVPG----HHLQPPAQFLLP------------QAQQSQPGLLPTPNLF-QLPQQTQGALLTSQPRAGLPTQAMTRPTLPDPHLSHPQPSKCLEPPS-------------HPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AETMSVDSSLPSP----------------------------NQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLA-NQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRT---------------------AGGGGGGGGAAPPLNSIPSVTPPPPA-----TTNSTNPSPQGS------HSAIGLTGLNPSAGSTMVGLSSGLSPALMGNNPLATIQGACCLMSPHCHQSCPLLGLEAPSPLLPQPCHPALPLTALLACSSPSVFGEGVRVLLLGSQWDRQEMGCSGRVHRGQGLPGLMYLQLSLSFSSPALASGGTLPLTSLDSSGNLVLGAAGAAPGSPSLVTSPLFLNHTGLPLLSAPPGVGLVSAAAAAVAATISSKSPGLSSSSSSSSSSSTCSEVAAQTSGGPGGPEAGSKAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00196-1", "uniprot_id": "PO2F2_MOUSE", "id": "Q00196-1", "name": "POU domain, class 2, transcription factor 2", "aln": "----MVHS-SMGAP-------------------------------------------------------EIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAPAAP-----------------------PPPQPAQPHLPQAQLMLTGSQLAG-----------------------------------------------------------------------------------------------------DIQQLLQLQQLVLVPG----HHLQPPAQFLLP------------QAQQSQPGLLPTPNLF-QLPQQTQGALLTSQPRAGLPTQ----------------PPKCLEPPS-------------HPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AETMSVDSSLPSP----------------------------NQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLA-NQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRT---------------------AGGGGGGGGAAPPLNSIPSVTPPPPA-----TTNSTNPSPQGS------HSAIGLSGLNPSAG-----------PGLWWN---------------------------------PAPYQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HZY4-1", "uniprot_id": "A0AC58HZY4_DANRE", "id": "A0AC58HZY4-1", "name": "POU domain protein", "aln": "MMDQMCQCPSSGVPPLNNSGSLTNVALFPISIYSVVMETAKMLGTTRESERRRDGGGKKVSEGRAQIKVDIRMSKAMEDDKMGTELPVDSTDSERNSPEASDQTQPMKTSPFCLSPAPSNTKVKGEEAAEMTSVHAP-----------------------PPP-PAQPALPHTQLMLAGSQLAGLAALLPAQQQLLLQ--QAQAQLLAAAVQQSNAAHAAHAAAAANQQQSQQQANQAAAQAQSQAKAEQAPPP--------------LLSQPIQLTA------QDIQQLLQLQQLVLMPG----HPLQSPAQFLLPQ----------AQAQQGQQGLLSTPNLI-PLPQQSPGSLLTTPPRLGLQAQHHLDDRLWSLQREKSVESVVSSAPSSAPPMSSAPTVTPHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGMAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLSD---------AETMAIDNMLPSP----------------------------SSLSSPLLGFEGLPGRRRKKRTSIETNVRIALERNFIS-NQKPTSEEILLMAEQLNMEKEVIRVWFCNRRQKEKRINPSSATPPLPTQPTAPTHKAPCYSPHMMS-SQALAQVATSLSTTAVSPTPSVACPLTS-------------------------SGHAAMSSAP-----SSVTPPPLS-----TVSPTPPSLSSP------GLNTGNTMMGVSTG---------MNQALISSN--------------------------------PLATMQALAAS------------------------------------------------------------GGQMSISALDGSGQMFLGGAG---GPGAGLRQSLFLNRPTLLPLARGAGMGLMGHRASPPPG------PDSCSISPCSSPASFCSLGEASPPHLGGAMAE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31503-1", "uniprot_id": "PO2F1_RAT", "id": "P31503-1", "name": "POU domain, class 2, transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LT-PAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIP------------------------------LSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHP----TTNLQPAQFIIS------------QTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPSITLTSQPTTPTRTIAATPIQTLPQSQTTPKRID---------TPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AENLSSDSTASSP----------------------------SALNSPGLGAEGLN-RRRKKRTSIETNIRVALEKSFME-NQKPTSEDITLIAEQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTS-SSPIKAIFP-SPTSLVATTPSLVTSSTATTLTVNPVLPLTSAAMTNLSLT------------------------GTTDSTSNN-TATVISTAPPASS-A--VTSPSLSPSPSAS-ASTSEASSASETSTTQTTS-TPLPSPLGASQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPGLMAPSQFAAGGALLSLNPGTLGGALSPALMSNSTLATIQ--------------------------ALASSGSLPITSLDATGNLVFAN---AGGAPNIVTAPLFLNPQNLSLLTSNP-VSLVSAAAASTGNSAPTASLHASSTSTESIQNSLFTVASASGAASTTTAASKAQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25425-1", "uniprot_id": "PO2F1_MOUSE", "id": "P25425-1", "name": "POU domain, class 2, transcription factor 1", "aln": "------------------------------------------------------------------------MNNPSETNKSSMESEDASTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSSEESGDSQQSSQPSSQPPSVQSAIPQTQLMLAGGQITGLTLT-PAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIP------------------------------LSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHP----TTNLQPAQFIIS------------QTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPSITLTSQPTTPTRTIAAASVQTLPQSQSTPKRID---------TPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AENLSSDSTASSP----------------------------SALNSPGLGAEGLN-RRRKKRTSIETNIRVALEKSFME-NQKPTSEDITLIAEQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTS-SSPIKAIFP-SPASLVATTPSLVTSSTATTLTVNPVLPLTSAAVTNLSLTDQDLRRGCSWEVLRSLPDRVTTTAGTTDSTSNNNTATVISTAPPASS-A--VTSPSLSPSPSAS-ASTSEASSASETNTTQTTS-TPLPSPLGASQVMVTTPGLQT-AAAALQGAAQLPANASLAAMAAAAGLSPGLMAPSQFAAGGALLSLSPGTLGSALSPALMSNSTLATIQ--------------------------ALASSGSLPITSLDATGNLVFAN---AGGAPNIVTAPLFLNPQNLSLLTSNP-VSLVSAAAASTGNSAPTASLHASSTSTESIQSSLFTVASASGPASTTTAASKAQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14859-1", "uniprot_id": "PO2F1_HUMAN", "id": "P14859-1", "name": "POU domain, class 2, transcription factor 1", "aln": "------------------------------------------------------------------------MNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQP-SVQAAIPQTQLMLAGGQITGLTLT-PAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIP------------------------------LSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHP----TTNLQPAQFIIS------------QTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRID---------TPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AENLSSDSSLSSP----------------------------SALNSP--GIEGLS-RRRKKRTSIETNIRVALEKSFLE-NQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTS-SSPIKAIFP-SPTSLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVT------------------------GTSDTTSNN-TATVISTAPPASS-A--VTSPSLSPSPSAS-ASTSEASSASETSTTQTTS-TPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSGALSPALMSNSTLATIQ--------------------------ALASGGSLPITSLDATGNLVFAN---AGGAPNIVTAPLFLNPQNLSLLTSNP-VSLVSAAAASAGNSAPVASLHATSTSAESIQNSLFTVASASGAASTTTTASKAQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U124-1", "uniprot_id": "A0AB32U124_DANRE", "id": "A0AB32U124-1", "name": "POU domain protein", "aln": "----MADGGAASQDESSG--------------------------------------------------PDSRMSNPSETSKCAMESGDENTGAQTNGLDFQRQTVQTTSAITNAHAQALL--------------------------------------------------------------QQLTLT-PAQQQLLLQ--QAQAQLLAAAVQ-HSAGQQSSTTGASISASAATPITQIP------------------------------LSQPIQITPQLLQ-QQQQQQNLNLQQFVLVQPGHPIATQLQPAQFIIS------------QTPQGQQSLLQAQNLLTQLPQ-SQANLLQTQPSITLATQPATPTRTIAATPIQSLAHTQTTPKHMD---------TPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDA------VCAENQTSDQALSSP----------------------------SSLGSPGLGMEGLN-RRRKKRTSIETNIRVALEKSFLEQNQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPNNGSAA-STPIKAIFS-PTTTLVPSTASLITSNTPTTMTVNPVLPLTSTSVSGISFT------------------------GTTLGSAINNTASVISTAPAATT-A--SSSPSLSPSPTAVQTSSSEQASAQETLTAVSQAPSSLASTLGTGQVMVAAP----SLSAALQGAAQLPTSASIAAMAAAAGLNPGLMASSQFAPGGALLSLAPGGLGSALSPALMSNSTLATIQGVW----------------------SALASSGTLPITSLDGSGNLLFANT-SAGSTPNLVTAPLFLNPQNLSLLASNP-VSLVSAGGAAG--AAGALNLHFTADAHQS------AVTTATMPASTITTASKAQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G8S3-1", "uniprot_id": "A0AC58G8S3_DANRE", "id": "A0AC58G8S3-1", "name": "POU domain protein", "aln": "----MADRGSTTQDERST--------------------------------------------------ADS-SGCPADLSKNTMES---AAQAQTNGVDAQKPSAGAASGAVGG-VQALLP--------------------------------------------------------------QLNLT-PAQ--------LLQTQLLAAVQQ--SAGQQSSTTGASISASAATPIT---------------------------------LSQPIQIAS---------PQGLNLPQFVLVQPGHSISTQIQP-QFILS------------PSAQGPTGLLQPQSLLTSLPQ-SQT----TQTSIALTTQAATPTRKIASMPAPAAP----TSKRVD---------GVCVEEAGDLEELEQFAKNFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLTD---------AENMSSDCVVSSA----------------------------SEMSPG--LSESLN-RRRKKRTSIETSIRIALERSFLEQSQKPSSEEITLIADQLSMEKEVVRVWFCNRRQKEKRINPPSSSAASPASAIKTIYS-TQTAAVS--------SGSNTLTVNPVVPLSSSGLSNLTLS------------------------GGALGHVTSNTPSVISMAPAIATPA--PAVTSQTPSSSAS-AGKQEIRAATSSAATLTQG---------AGPLLVTGAG---------LGGANLTT--------FATGLNPTIITPSQLAQGGALLSLAP-ALGNTLSPALMNNNALATIQ--------------------------ALASGGAFPLTSIDGNTSLLFANTSAANSTPSLVTTPFFLNPSGLSLLPAN----FLSAGGAGG----GALNLHLTSDVQQN------LVATTT---KGVALASKAQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9UKI9-1", "uniprot_id": "PO2F3_HUMAN", "id": "Q9UKI9-1", "name": "POU domain, class 2, transcription factor 3", "aln": "----MVNLESMHTDIK-------------------------------------------------------MSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRP-------------------------------------------------------------------------------------------------CHLSQGPAMMSGNQMSGLNASP-------------------------------------------CQDMASLHPLQQLVLVPG-----HLQSVSQFLLS------------QTQPGQQG---LQPNLLPFP-QQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKH------LPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AESSPSDPSVSTP----------------------------SSYPSLSEVFG----RKRKKRTSIETNIRLTLEKRFQD-NPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN----CPVAT-PIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSP------------------------GSGLHASSPTASQNNSKAAVN---------SASSFNSSGS-------WYRWNHSTYLH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31362-1", "uniprot_id": "PO2F3_MOUSE", "id": "P31362-1", "name": "POU domain, class 2, transcription factor 3", "aln": "----MVNLEPMHTEIK-------------------------------------------------------MSGDVADSTDTRSTFGQVEPGNDRNGLDFNRQIKTEDLGDSLQQTLSHRP-------------------------------------------------------------------------------------------------CHLSQGPTMMPGNQMSG--------------------------------------------------DMASLHPLQQLVLVPG-----HLQSVSQFLLS------------QTPPGQQG---LQPNLLSFP-QQQSTLLLPQTGPGLASQAVGRPGLSGSSLEPHLDAPQHLPGPKH------LPGPGGNDEPTDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLND---------AESSPSDPSASTP----------------------------SSYPTLSEVFG----RKRKKRTSIETNIRLTLEKRFQD-NPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN----CPVAT-PVKPPIYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSP------------------------GSGLHASSPTASQNNSKAAMNSS-------SSSSFNSSGS-------WYRWNHPTYLH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BJD9-1", "uniprot_id": "A0A8M2BJD9_DANRE", "id": "A0A8M2BJD9-1", "name": "POU domain protein", "aln": "-----------------------------------------------------------------------MSTDAVEQTESQHEQADIE----QNGIDFTRQIKTENLNDSPHSGSSHKT-------------------------------------------------------------------------------------------------CHLTQGSPLPPG-QLTG--------------------------------------------------EMPSLHPLPQLVLMPGS----HLSSPSSFLLS------------QAQSGHQGLSLLPPNLLSLPSQTQTGLLPHQPGLALTPQAMGRSGLAGSSMDGHLDMS-HLQVPKH------VGSP--QDEPNDLEELEQFAKAFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLSD---------AENSPSD-TMTNT----------------------------TTLPPLMEGYG----RKRKKRTSIETNIKLTLEKRFLD-NPKPNSEEITLISEQLAMEKEVVRVWFCNRRQKEKRIY----CPVSTSPIKPHNFNPRLPSTSRSFSPLTS--------GGVSSSSSPGSPSRGSSP------------------------GTLSTTSSPLTAQS-----VN-----------QTFNTAGS-------WYRWNTASYHH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK71-1", "uniprot_id": "PDM2B_DROME", "id": "Q9VK71-1", "name": "POU domain protein 2, isoform B", "aln": "----MPLLLATTLANN--------------------------------------------------SHHQHLSTTATETAAAAATAKAAATAAAAATATMLLTSPTAATHCLAAATSAAGVNVQITGQGVSATLNDDQ---------------------LQLPANYAANVGHLNGFNPKDNCPPVPPTSERAFEGLLRLPQIQVKQEFMESPPERPSCHPMNHQQAPANSALATSCRGKTILNPWYLRPADGIGYHNYNSNNNNSGSGEINKDVSQQMTSACGGSDGQTCLPVSYFGMETLASVKQRQKSLPDFLIPLHEIMFQQQHHYQQRTMGTLINSLPPGLVGYPPQKTETFKSLTPPKALQHHQNNQNHQIPQNHTGDHSFVRHFHERDR-------LIREHQLKHQQLRDVEEVLQEQEQDEEQEHETLRKPHVVPSELEHNHHWHGVVCDANGHATRLLHIAPPRAGPTPLPTHQQPPVGEVLPPNSTSFSTIVDPPKEPSIYEQPAPNGRHCRPANKVMRHMSNSPTPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSS-KRQARELDSELENEVLDLAPPPKRLAEEQEEEKVASVNPPQPVAFAPEEMHQALQLQLHSYIEMVRQLAPEAFPNPNLATQFLLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKSQQRTPPNSMTANSLGMSSAVMTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINPSLDLDSPTGTPLSSHAFGYPPQALNMSHMQMEGGSGSFCGSSISSGE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .*::. : * . * : : :*.::*:. : :* . : * . :. .:* *.. : .:. :. : ::. :. .. . . . . . . : :. .:* . . : : : . :. . : : : * : *: :..:* : . . ", "identical_positions": 13, "similar_positions": 74, "identity": "1.33%" }, { "cls_id": "homologset.agr.FB:FBgn0004395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV40-1", "uniprot_id": "D3ZV40_RAT", "id": "D3ZV40-1", "name": "", "aln": "MAQGIADPQHPGHRPQRSLGIVVLHFSSDAVPTVKFHPKGGPQLPATFAAVRGVFTFSWRGAGAVGLRRGPRRLNNKRGAAKRQEDRTMSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTT-VEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDTCQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHIEPPPLSDDVPPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRSSGLASPPHLCSSPPGPSRKISNLEGLVFPGEASLAPGSYKKAPGCEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPS-PAGTSSAPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPSNITIGGSLLQSSAPVNIPGSLGSSASFHSAS---PSPPVSLS---------SHFLQQPQGHLSQSENTFLGTSAS-HGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGP--------GAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTR--TVLPCQHAVLCELCAEGS-ECPVCQPGRAHALQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL48-1", "uniprot_id": "UNK_MOUSE", "id": "Q8BL48-1", "name": "RING finger protein unkempt homolog", "aln": "----------------------------------------------------------------------------------------MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTT-VEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPLSDDVQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSGLGSPSHLCSSPPGPSRKASNLEGLVFPGESSLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDVLGILPVGSPLTSSISSSITSSLAATPPS-PAGTNSTPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSAVPHPSSVTIGGSLLQSSAPVNIPGSLGSSASFHSAS---PSPPVSLS---------SHFLQQPQGHLSQSENTFLGTSAS-HGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGP--------GAAELARLRQELDEANGTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALELRVKKLQEELERLHTVPEAQTLPAAPDLEALSLSTLYSIQKQLRVHLEQVDKAVFHMQSVKCLKCQEQTR--AVLPCQHAVLCELCAEGS-ECPVCQPSRAHALQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0B0-1", "uniprot_id": "UNK_HUMAN", "id": "Q9C0B0-1", "name": "RING finger protein unkempt homolog", "aln": "----------------------------------------------------------------------------------------MSKGPGPGGSAASSAPPAATAQVLQAQPEKPQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEALQNGQTT-VEGSIEGQSAGAASHAMIEKILSEEPRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQSGSCPRGPFCAFAHVEQPPLSDDLQPSSAVSSPTQPGPVLYMPSAAGDSVPVSPSSPHAPDLSALLCRNSSLGSPSNLCGSPPGSIRKPPNLEGIVFPGESGLAPGSYKKAPGFEREDQVGAEYLKNFKCQAKLKPHSLEPRSQEQPLLQPKQDMLGILPAGSPLTSSISSSITSSLAATPPS-PVGTSSVPGMNANALPFYPTSDTVESVIESALDDLDLNEFGVAALEKTFDNSTVPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSAS---PSPPVSLS---------SHFLQQPQGHLSQSENTFLGTSAS-HGSLGLNGMNSSIWEHFASGSFSPGTSPAFLSGP--------GAAELARLRQELDEANSTIKQWEESWKQAKQACDAWKKEAEEAGERASAAGAECELAREQRDALEVQVKKLQEELERLHAGPEPQALPAFSDLEALSLSTLYSLQKQLRAHLEQVDKAVFHMQSVKCLKCQEQKR--AVLPCQHAALCELCAEGS-ECPICQPGRAHTLQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3S7-1", "uniprot_id": "D4A3S7_RAT", "id": "D4A3S7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MAPSTTARTFTVPSTMRPPAC-------VPTVTMFIP------------------------------------------------LLP---RCPYLHRTTGDTERKYHLRYYKTGTCIHETDARGHCVKNGLHCAFAHGPLDLRPPVCDIRELQAQEALQNGQLSGGDGVPDLQPGVLASQAMIEKILGEDPRWQDSNFVLGSYKTEQCPKPPRLCRQGYACPHYHNSRDRRRNPRRFQYRSTPCPSVKHGDEWGEPSRCDVGDSCQYCHSRTEQQFHPEIYKSTKCNDMRQTGYCPRGPFCAFAHIEKS---------------------LGMVNEWS-------------------CRDLSSNSTSAYSS-QPGSAK----------------------------RKD----------------SPSEGSQKATE----DSKQNHLAVFSVVHPLAPSISSSVASSLASSTGSGSSSPTTLPNLPARALPLDPAGNTVEAVIGSALD-LRLSDINIASLDKDLEEQD-----LGLTGPRSLAGSAPVTIPGSLPRSPSLHSSSSLSTSPLSSLSQSLSGPLVSSAMTPPQQPPPLRSEPATLGSTASSYSSLGLNGVPGSIWD-FVSGSFSPSPSPILNSGPSASSSASPNSAELARVRRQLDEAKRKIRQWEESWQQVKQACDAWQREAQEAKERARVADSDRQLALQRKEEVEAQVKQLQEELEGLGLSSLP-GLRSLGDISDIPLPKLHSLQSQLRLDLEAVDGVIFQLRAKQCVACQERAHGTVLRPCQHRVLCEPCAASTPECPYCK---GQPLPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWH2-3", "uniprot_id": "UNKL_MOUSE", "id": "Q5FWH2-3", "name": "Putative E3 ubiquitin-protein ligase UNKL", "aln": "-------------------------------------------------------------------------------------------------MPSVSKAAAAALSGSPPQTEKPTHYRYLKEFRTEQCSLFLQHKCSQHRPFTCFHWHFLNQRRRRPLRRRDGTFNYSPDIYCSKYDEATGLCPDGDECPYLHRTTGDTERKYHLRYYKTGTCIHETDARGHCVKNGLHCAFAHGPLDLRPPVCDIRELQAQEALQNGQLSGGDGVPDLQPGVLASQAMIEKILGEDPRWQDSNFVLGSYKTEQCPKPPRLCRQGYACPHYHNSRDRRRNPRRFQYRSTPCPSVKHGDEWGEPSRCDGGDSCQYCHSRTEQQFHPEIYKSTKCNDMRQTGYCPRGPFCAFAHTEKS---------------------LAMVNEWS-------------------CRDLSSNSTSAYSS-QPGSAK----------------------------RKD----------------SPSEGSQKATE----DSKQNHLAVFSVAHPLAHSISSSVASSLASSTGSGSSSPTTLPTLPARALPLDPAGNTVGAVIGSALD-LRLSDINIASLDKDLEEQD-----LGLTGPRSLAGSAPVTIPGSLPRSPSLHSSSSLSTSPLSSLSQSLSGPLVSSAMTPPQQPPPLRSEPATLGSAASSYSSLGLNGVPGSIWD-FVSGSFSPSPSPILNSGPSASSSASPNSAELARVRRQLDEAKRKIRQWEESWQQVKQACDAWQREAQEAKERARVADSDRQLALQRKEEVEAKVKQLQEELEGLGLSSLP-GLQSLGDISDIPLPKLHSLQSKLRLDLEAVDGVIFQLRAKQCVACQERAHGTVLRPCQHRVLCEPCAASTPECPYCK---GQPLPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9P5-4", "uniprot_id": "UNKL_HUMAN", "id": "Q9H9P5-4", "name": "Putative E3 ubiquitin-protein ligase UNKL", "aln": "-------------------------------------------------------------------------------------------------MPSVSKAAAAALSGSPPQTEKPTHYRYLKEFRTEQCPLFSQHKCAQHRPFTCFHWHFLNQRRRRPLRRRDGTFNYSPDVYCSKYNEATGVCPDGDECPYLHRTTGDTERKYHLRYYKTGTCIHETDARGHCVKNGLHCAFAHGPLDLRPPVCDVRELQAQEALQNGQLGGGEGVPDLQPGVLASQAMIEKILSEDPRWQDANFVLGSYKTEQCPKPPRLCRQGYACPHYHNSRDRRRNPRRFQYRSTPCPSVKHGDEWGEPSRCDGGDGCQYCHSRTEQQFHP---ESTKCNDMRQTGYCPRGPFCAFAHVEKS---------------------LGMVNEWG-------------------CHDLHLTSPSSTGSGQPGNAK----------------------------RRD----------------SPAEGGPRGSEQ---DSKQNHLAVFAAVHPPAPSVSSSVASSLASSAGSGSSSPTALPAPPARALPLGPASSTVEAVLGSALD-LHLSNVNIASLEKDLEEQDGHD--LGAAGPRSLAGSAPVAIPGSLPRAPSLHSPSSASTSPLGSLSQPLPGPVGSSAMTPPQQPPPLRSEPGTLGSAASSYSPLGLNGVPGSIWD-FVSGSFSPSPSPILSAGPPSSSSASPNGAELARVRRQLDEAKRKIRQWEESWQQVKQVCDAWQREAQEAKERARVADSDRQLALQKKEEVEAQV--------------------------------------------------IFQLRAKQCVACRERAHGAVLRPCQHHILCEPCAATAPECPYCK---GQPLQW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86B79-1", "uniprot_id": "UNK_DROME", "id": "Q86B79-1", "name": "RING finger protein unkempt", "aln": "-----------------------------------------------------------------------------------------------------MLANETNKLLLSSQQEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSADNYCTKYDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHGMQDQRPPVYDIKEL---ETLQN-----AESTLDS-TNALNALDKERNLMNEDPKWQDTNYVLANYKTEPCKRPPRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYCHTRTEQQFHPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCS-----------------------------------------------MDDPRENSLSASLANTSLLTR------------------------------------------------------------------SSAPINIPNTTLSNSINDFNSGSFAVNIPS--SSLTYSPTNHANLFNVDAFNYGGSNKLSNSLS--------------------------ATQNDSSLFFPSRIISPG-FGDGLSISPSVR--ISELNTIR---------DDINSSSVGNSLFEN--TLNTAKNAFSLQSLQSQNNSDLGRITNELLTKN-------------------AQIHKLNGRFEDMACKLKIAELHRDKAKQEAQEWKERYDLAQIQLNLPAELRDLSIQKLKQLQSKLR----------------------------------------TDLEEVDKVLYLENAKKCMKCEENNRTVTLEPCNHLSICNTCAESVTECPYCQVPVITTHT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. :* . * : * .**:****:*****:******** *:*:**::* *.*********** * *.** *::** *:*** :. : . : .:::.*:*:**:: :**..**** * :************ ****:*:**.**:.:***:***.****:***:*..*: ** *****:******** :******::*:* ***. ****** * . * . . . : . : . : *:.. :.*:* . * . . * *. : . . . : .:*. . * .: : ** : . *: .. * :: . : .: *.:: . .. .*:. .* :.. :: . *:: ::. .::: .:: * .:.** .: *:.. : * : . :*: :: . :: :: :: .: :*: *.*. : .: **:* :*: ** *** *: . ", "identical_positions": 166, "similar_positions": 163, "identity": "17.97%" }, { "cls_id": "homologset.agr.FB:FBgn0004396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HA2-1", "uniprot_id": "CR3L1_RAT", "id": "Q66HA2-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 1", "aln": "MDAVLEPFPADRLFPGSSFLDLGDLNES-DFLNNAHFPEHLDHFVENMEDFSNDLFSSFFDDPVLDEKSPLLDMELDSP----AP-GIQAEHSYSLSGDSAPQSPLVPVKMEDT--TQDMEHGAWALGNKLCSIMVKQEQSPELPVDPLAASSAMAAAT-MATPPLLGLSPISRLPIPHQAPGEMTQLPVIKAEPPEMSQFLKVTQE----DLVQMPPTPPSSHGSDSDGSQSPR------SLPPS-SPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTSENNELWKKVETLETANRTLLQQLQKLQTLVTSKISRPYKMAATQTGTCLMVAALCFVLVLGSLAPCLPAFSSGSKTVKEDPVAADSVYAASQMPSRSLLFYDDGAGSWEDGHRGALLPVEPPEGWELKPGGPAEPRPQDHLRH---------DHADSIHETTKYLRETWPEDTEDNGASPN-FSHPKEWFHDRDLGPNTTIKLS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z125-1", "uniprot_id": "CR3L1_MOUSE", "id": "Q9Z125-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 1", "aln": "MDAVLEPFPADRLFPGSSFLDLGDLNES-DFLNNAHFPEHLDHFVENMEDFSNDLFSSFFDDPVLDEKSALLDMELDSP----AP-GIQAEHSYSLSGDSAPQSPLVPVKMEDT--TQDVEHGAWALGNKLCSIMVKQEQSPELPVDPLAASSAMAAAAAMATPPLLGLSPMPRLPIPHQAPGEMTQLPVIKAEPPEMSQFLKVTPE----DLVQMPPTPPSSHGSDSDGSQSPR------SLPPS-SPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTSENNELWKKVETLETANRTLLQQLQKLQTLVTSKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPAFSSGSMTVKEDPIAADSVYAASQMPSRSLLFYDDGAGSWEDG-RGALLPVEPPEGWELKPGGPAEQRPQDHLRH---------DRADSIHETTKYLRETWPEDTDDNGTSPN-FSHP-EWFHDRDLGPNTTIKLS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BA8-1", "uniprot_id": "CR3L1_HUMAN", "id": "Q96BA8-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 1", "aln": "MDAVLEPFPADRLFPGSSFLDLGDLNES-DFLNNAHFPEHLDHFTENMEDFSNDLFSSFFDDPVLDEKSPLLDMELDSP----TP-GIQAEHSYSLSGDSAPQSPLVPIKMEDT--TQDAEHGAWALGHKLCSIMVKQEQSPELPVDPLAAPSAMAAAAAMATTPLLGLSPLSRLPIPHQAPGEMTQLPVIKAEPLEVNQFLKVTPE----DLVQMPPTPPSSHGSDSDGSQSPR------SLPPS-SPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETFTSENNELWKKVETLENANRTLLQQLQKLQTLVTNKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPEFSSGSQTVKEDPLAADGVYTASQMPSRSLLFYDDGAGLWEDG-RSTLLPMEPPDGWEINPGGPAEQRPRDHLQH---------DHLDSTHETTKYLSEAWPKDG-GNGTSPD-FSHSKEWFHDRDLGPNTTIKLS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QDP7-1", "uniprot_id": "CR3L2_RAT", "id": "Q6QDP7-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "aln": "-MEVLESGEQSVLQWDRKLSELSEPGETEALMYHTHFSELLDEFSQN-------VLGQLLNDPFLSEKSVSMEVEPSPT--SPAP-LIQAEHSYSLSEEPRAQSPFTHVAASDGFNDEEVESEKWYLSTEFPSATIKTEPITEEQPPGLVPSVTLTITA--ISTPFEKEESPLDMSAGGDSSCQ-TLIPKIKLEPHEVDQFLNFSPKEASVDQLHLPPTPPSSHSSDSEGSLSPNPRLHPFSLSQAHSPGRAMPRGPSALSTSPLLTAPHKLQG-SGPLVLTEEEKRTLIAEGYPIPTKLPLTKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSLFQGYGLYPSATKMALPSQHPLSEPYTASVVRSRNLLIYEEHSSLEESS--SPASAGELG-GWDRGSSLLRASSGLEALPE--------VDLPHFIISKETSLEKSVLLELQQHLVSSKLEGNETLKVVELERRVNATF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH52-1", "uniprot_id": "CR3L2_MOUSE", "id": "Q8BH52-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "aln": "-MEVLESGEQSVLQWDRKLSELSEPGETEALMYHTHFSELLDEFSQN-------VLGQLLSDPFLSEKSESMEVEPSPT--SPAP-LIQAEHSYSLSEEPRTQSPFTHAATSDSFNDEEVESEKWYLSTEFPSATIKTEPITEEQPPGLVPSVTLTITA--ISTPFEKEESPLDMNAGGDSSCQ-TLIPKIKLEPHEVDQFLNFSPKEASVDQLHLPPTPPSSHSSDSEGSLSPNPRLHPFSLSQAHSPARAMPRGPSALSTSPLLTAPHKLQG-SGPLVLTEEEKRTLVAEGYPIPTKLPLTKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHPLSEPYTASVVRSRNLLIYEEHAPLEESS--SPASAGELG-GWDRGSSLLRASSGLEALPE--------VDLPHFLISNETSLEKSVLLELQQHLVSSKLEGNETLKVVELERRVNATF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70SY1-1", "uniprot_id": "CR3L2_HUMAN", "id": "Q70SY1-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "aln": "-MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQN-------VLGQLLNDPFLSEKSVSMEVEPSPT--SPAP-LIQAEHSYSLCEEPRAQSPFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITA--ISTPLEKEEPPLEMNTGVDSSCQ-TIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQG-SGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESS--SPGSAGELG-GWDRGSSLLRVS-GLESRPD--------VDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L224-1", "uniprot_id": "CR3L2_DANRE", "id": "A1L224-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "aln": "-MEIMDSGEP-FLQWDKNLSELSEAGEN-DILYSTHFTDLLDDLSQEA------LLGQLLSDPFLSGRGDAMDTEEELTRASPVPPHIQAEHSYSLCGDSRPQSPLSHLPGEPGSDAADSESDEWPMEQE--DKGIKMEPLLCVPLPALTLTVTPAGSA--PEPVIDSCDSAQSLSLP-QVKED-SNSPQIKLEPHEVDQFLNLSPK--GLECLQMPPTPPSSVGSDSEGSQSPVHPCAPASPTQTPAVLKVAPRAPSSLSSSPLLTAPHKLQG-SGPLLLTEEEKRTLIAEGYPVPTKLPLSKAEEKALKKIRRKIKNKISAQESRRKKKEYVDALEKKVETCSNENHELRRKVENLECTNKSLLQQLHSLQAVVAGKVPRSCRVTGTQTSTCLMVVVLCFSLFLGSFYPGLSPCSSITKADLSREISIHDSYTT-TVKSRSLLSIQEPGGLDEPH--PIGLGGEYP-EWDRQADVMAAWRFEQQHKEEEAELHKAEHRPLLLSTNETHAQKAILIDLHTHRS------NETAKVIQLDRTVNETS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29747-1", "uniprot_id": "CREBA_DROME", "id": "P29747-1", "name": "Cyclic AMP response element-binding protein A", "aln": "-----------MEFYDGDLKDIWDSDLDPESLKISPDHDMHDWLFDR----------DVKDPTVILNDKLISDALLNGT----QP--IKTEHSYSLSSDVDS---LPDSPKSLQAKIEDMDDECFPAISPKTATNGRVTIDPKYLTFHVPPTHATPISRLSSNPALNTSVADLTRSSGLQSLQAHQPHHGSGSSHVVVANLEHFQLPQHLYDNDCSSSVSSLRDGSMSPDICSDIEIDESAIKDEPMSPDSSCPASPTSQASSSQHQLSLNLAHLQSEMLFEPKHCGLLLTASSNSNNSLIKSQQRQ---QQILGQDNLLMAKMEIKSEKQSTSNSSDKSHAHGYGIPLTPPSSLPSDDSEGNLSPEHLFAPLSPNATVSISVANPAGGESSVRVSRTAASITRSSSGSASASGSSTSSTVTTTRQPIHTPLISSQPKGSTGTLLLTEEEKRTLLAEGYPIPQKLPLTKAEEKSLKKIRRKIKNKISAQESR-----RKKKEYMDQLERRVEILVTENHDYKKRLEGLEETNANLLSQLHKLQALVSKHNVKKS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :: : . : : : * : :. .. . ..: : . . * *::******. : . : . : : : : : . : . : . : . : . : :: :. : ..... .* * . * . : . ..:: ::*. . :* .. ::: :. *:: . ..* :: .: ::: : : :: * : :*:. :. :*. .: : .. ::* : . :. ::.. : .. .: .. .* : : : .** :: : . . . : : . : . . ", "identical_positions": 23, "similar_positions": 138, "identity": "4.15%" }, { "cls_id": "homologset.agr.FB:FBgn0004397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85972-1", "uniprot_id": "VINC_RAT", "id": "P85972-1", "name": "Vinculin", "aln": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVGKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPA---KAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARALASQLQDSLKDLKTQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGAA-NKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP-----DFPPPPPDLEQLRLTD---ELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSK--------------------------------------------------------------------GNDIIAAAKRMALLMAEMSRLVRGGS-GTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAG-FTLRWVRKTPWYQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64727-1", "uniprot_id": "VINC_MOUSE", "id": "Q64727-1", "name": "Vinculin", "aln": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPA---KAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTA-NKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP-----DFPPPPPDLEQLRLTD---ELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSK--------------------------------------------------------------------GNDIIAAAKRMALLMAEMSRLVRGGS-GTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAG-FTLRWVRKTPWYQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18206-1", "uniprot_id": "VINC_HUMAN", "id": "P18206-1", "name": "Vinculin", "aln": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPA---KAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTA-NKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP-----DFPPPPPDLEQLRLTD---ELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGS-GTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAG-FTLRWVRKTPWYQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46037-1", "uniprot_id": "VINC_DROME", "id": "O46037-1", "name": "Vinculin", "aln": "MPVFHTKTIESILDPVAQQVSRLVILHEEAE-DGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQD-------------------------------------------------------------------------------------------------SYPIRKLAD-------------EVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAA-------GSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAIAPPQPPPLPTSLPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGLHQEVRQWSSK--------------------------------------------------------------------DNEIIAAAKRMAILMARLSELVLSDSRGSKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLG-AQGSDEDRE-ATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:******:*****:*:***:***.* **:*:***: ** .*.***:***:**::*:::::*:**::***.*: :**.*. * :*::**:***** ***. **:******.***.*** ***:******: ** :*:**:****::***:** : *:*.* ::*: : :. *::***** * :**..:: ** * *:**.:**::: :.:.:* *** :***: . :** *::*********::***: .: .:*: :*..*::**: ** :* * *..**:*:**::*:* ::.* * :: : * :*.* *::*::..* :**::***:**:*.:*.: : : :*:: .::** . * ::* ::*::*** :*:::* ::* *:*: **. :* **:::*: * : :: **.*::* * * *..* *: *.** :.* :**: :*:*:.:.: : * *.:**:* :: *. * .:*.**: *:::: *:: .*.: . *:. .** *:. **. .* : :*. . .****::**.** :. **.:** **::.:*:*: *.* :* * *:* *. .::.:*** :: . *: *: *** :* .::.*** **:*****:*.:***** * * ::**::.*.:::..** *** ** **:**. :: :* *:** * :**:*: * :* .:*** *:*. *:*:: * ***:****. :.* ****** .**: :: ***:::*** **:*.*:**** .*:*********:***.:*.** ..* *:** ** **.**:**::*******:*:****:****************.*************** :: ***: * ****** ************** **.******:* *:***: **** ", "identical_positions": 462, "similar_positions": 307, "identity": "40.21%" }, { "cls_id": "homologset.agr.FB:FBgn0004401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LV60-1", "uniprot_id": "F1LV60_RAT", "id": "F1LV60-1", "name": "", "aln": "MFNQQLQQ-----QQQLQQLQQQQLQQQ---QQQILQLQQLLQQSPPQASLSMPVSRGLPQQSSPQQLLNLQGLNSTSLLNGSMLQRALLLQQLQGLDQFAMPPATYDSASLTMPTAALGNLRAYNVTAPNLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGIPINPSQHNHSGRNSQKQPRTPSSTTPNHKDSSSQTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDGLASEPQVHEPEPEPFEALEPPAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVLQIQT-----------------LSKLQKQAQTQTSPEHLAPQQNQVQPQVR--SQPQWQLQP-----------------WETDPPKQAQAQTQP----QPLWQAQSHKQAQTQTQTHPQVSTQAQPQEQ------------TSEKTQDQPQTWPQGSAPPPEQASVPACATEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRSQEPSAGGLDVGECEKRAGEVLGMWGAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSASATPALASTPSKQSLQFFCYICKASCSSQQEFQDHMSEAQHQQRLGEMQHSSQTCLLSLLPMPRDILERET-----EDPPPKRWCNTCQVYYMGDLIQHRRTQEHKVAKQSLRPFCTICNRYFKTPRKFVEHVKSQGHKDKAQELKTLEKETGSPDEDHFITVDAVGCFESGQEEDEDDDEEEEEEIEAEEEFCKQLQSRETSSEQWKDSETYSPNTAYGVDFLVPVMGYVCRICHKFYDSNSEFRLSHCKSLAHFENLQKYKAK----NPSPPTRPVSRKCAINARN------------ALTALFTSSSGSSRQ-----------PSPQDTVKIPSKVTCFPEAVILAFRARIHRHA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULV3-1", "uniprot_id": "CIZ1_HUMAN", "id": "Q9ULV3-1", "name": "Cip1-interacting zinc finger protein", "aln": "MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETED-----EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDD--EDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAK---NPSPTTRPVSRRCAINARN------------ALTALFTSSGRPPSQ-----------PNTQD--KTPSKVTARPSQPPLPRRSTRLKT------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AS23-1", "uniprot_id": "A0A8M3AS23_DANRE", "id": "A0A8M3AS23-1", "name": "", "aln": "-------------MVRMFNPHQHQQQQQHQFHQHLRQLQQLFQQQTPPPPPPPPP----PPQPPPAHHITHH-HQAARYPHAAPPHTNTAHTRPMAVPAPAPPPARMVNLCSATQTIIAPNPMLQGALLMQQMQGSMRGFAMGGQQFPPFFAAGSRASLLGPVPMGVAIK----------------TPHMGFPRHFTPHARYFPNDYQTPQPDRKREIEQKSANISSGHS--------AASSSNGQPEAARSSNGQSAAKSSSSNDQSAANSSSNGQSVASSSNGQSEAKSSSSSSSSRADEAVAVADPGSQ--------------------------GSSEQPDEPAAKKHKTQESEEPLEKDSAENTECKSPADAG---------------------------------------------------------------------------------------DSLPEESVVNEPPATEAEEQCQADKQTDAADVDQPISGAPAD------------------------------------AGSSDSVSAVKQPE----------AAPVQHQLTDTAAAAESSSS-----FFCYICNITCHNQQNFQSHMNGLTHQQKMMEIQHMSNACLVTLLPRVQESLQGAARKDGEKRPGLQRWCSTCQTHFTSNVMEHRRTKEHKRFSRSSSSSCTVCKLNFRTAREFVEHMQSAEHKQRVQQLW---KESGSGSVEELNTVMLLGEDDGEFCSDDER----EDEENGKEGLSAQM---EVTMEDLDEDEEFDSDTVYGSSFVVPVSGFLCRLCDQFYHYESSARHAHCKTLKHFQNLKRYKALKKHEDSGSTSAEAAEEVAVAAAEGLLIAEESSVDPSASPITNTSSTPPQQEEKLEPEETLKPEPEPESELEEKLEPEPELEERSSERGRGRTSAKRRGRGGRRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41073-1", "uniprot_id": "PEP_DROME", "id": "P41073-1", "name": "Zinc finger protein on ecdysone puffs", "aln": "-----------MVSVKVNGNPQNRLVNNAKVNGNMAFRGNQNRNRNFGGGNNNYGGPMGANRMGGMNMSPWESQNPGGGQFGNNMRQGGGQMNAQAINLANNLLNNLFRNQNPPSLLDLPRGGGGMGNRNQRGGPMVSRGGGAGNRLNNRRGQGGGFQNRGATGSGPKPPP---------------KQGGGGIRKQNAFDRAKKLLAKNANQNKKKEPTPGEKKIESPTK---------ESPYASVPNDMFYCHLCKKHMWDANSFENHIKGRTHLMMREGIEESYRLKANMIRQEAKIAEQLKSIEFDRLKRMG-----------------------KSKQRQLDYCTMCDLNFHGHISTHRKSEGHLQLKKFLHPK-------------------------------------------------------------------------------------CIECNKEFATRIDYDTHLLSAEHLKKAAENNTKVGERKRQTLPISTE---------------------------------EEETRDLRLPQKRKKK--------PVKKEGEAADGEAKKEGAGD-------GEGAEGDEAEGEEAKEGEEAADETKEGDELNESQEEEEVALPVDPEDCILDFN-----DGDEIPSEVDTRLPKYN-----WQRAVGPGLISKLECYECSVCSKFFDTEVTAEIHSRTATHHRNFLKFINEKSSDTKIAQKRAAAALEENERKKRKVEEAEAPAAEGAAEETTEGAEGELYDPSEATGDDEDVEMVDDNAEG------EGEGEGDEEAEAEVEEDGAGQDNGEEEMEAQEEEGQEGEQEPEPEPAPVQTPAPAEPAPPAKTPAKTPTKAAAPAAVASPAAAATSADAS-----------PSPAKKATPARAAAGAKATPQRQRARGRYNRY-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *:: :: : :: : :: . : . :. . : . .: . . : .: . . *. * . .: . : : : ..* . . . . *: .. : : . : . .: : : . :: : : . . . . : : .. . : : : . : .... : . : .: :. . . : .. . .: . .: . :: :. . . :. *::. .: ::* .: : . .* : :*: .: *::*. * * * :: *: . :: .. .. :. . . .: : : * :: . : : . * . :: * . .. . :. : : : :: : :... .. . * * : :. :: . . *.. . ", "identical_positions": 21, "similar_positions": 181, "identity": "2.22%" }, { "cls_id": "homologset.agr.FB:FBgn0004403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62263-1", "uniprot_id": "RS14_HUMAN", "id": "P62263-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62264-1", "uniprot_id": "RS14_MOUSE", "id": "P62264-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13471-1", "uniprot_id": "RS14_RAT", "id": "P13471-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPRKGKDKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A290-1", "uniprot_id": "D4A290_RAT", "id": "D4A290-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPCKGTEKKEEQVISLGPQVAEGENVSGVCHIFASFSDTFVHVTDLSGKETICRVTGGMKVKADREESSPYAAMLAAQDVAKRSKELGITALHIKLWATGGNRTKAPGPGAQSALRALARSGMKIGQIEDVTSIPSDSTQRKKGCCGRCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKA0-1", "uniprot_id": "RS14A_DROME", "id": "C0HKA0-1", "name": "Small ribosomal subunit protein uS11A", "aln": "MAPRKAKVQKEEVQVQLGPQVRDGEIVFGVAHIYASFNDTFVHVTDLSGRETIARVTGGMKVKADRDEASPYAAMLAAQDVAEKCKTLGITALHIKLRATGGNKTKTPGPGAQSALRALARSSMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39516-1", "uniprot_id": "RS14B_YEAST", "id": "P39516-1", "name": "Small ribosomal subunit protein uS11B", "aln": "MAND-------------LVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06367-1", "uniprot_id": "RS14A_YEAST", "id": "P06367-1", "name": "Small ribosomal subunit protein uS11A", "aln": "MSN--------------VVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. :.. * **.:*:***.***********:***.************:*:************* :.* :****:*:*: ****.:**:****.*:********.::**:*****.:*****::* * ** *", "identical_positions": 92, "similar_positions": 32, "identity": "60.93%" }, { "cls_id": "homologset.agr.FB:FBgn0004404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62263-1", "uniprot_id": "RS14_HUMAN", "id": "P62263-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62264-1", "uniprot_id": "RS14_MOUSE", "id": "P62264-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13471-1", "uniprot_id": "RS14_RAT", "id": "P13471-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPRKGKDKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A290-1", "uniprot_id": "D4A290_RAT", "id": "D4A290-1", "name": "Small ribosomal subunit protein uS11", "aln": "MAPCKGTEKKEEQVISLGPQVAEGENVSGVCHIFASFSDTFVHVTDLSGKETICRVTGGMKVKADREESSPYAAMLAAQDVAKRSKELGITALHIKLWATGGNRTKAPGPGAQSALRALARSGMKIGQIEDVTSIPSDSTQRKKGCCGRCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKA1-1", "uniprot_id": "RS14B_DROME", "id": "C0HKA1-1", "name": "Small ribosomal subunit protein uS11B", "aln": "MAPRKAKVQKEEVQVQLGPQVRDGEIVFGVAHIYASFNDTFVHVTDLSGRETIARVTGGMKVKADRDEASPYAAMLAAQDVAEKCKTLGITALHIKLRATGGNKTKTPGPGAQSALRALARSSMKIGRIEDVTPIPSDSTRRKGGRRGRRL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39516-1", "uniprot_id": "RS14B_YEAST", "id": "P39516-1", "name": "Small ribosomal subunit protein uS11B", "aln": "MAND-------------LVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06367-1", "uniprot_id": "RS14A_YEAST", "id": "P06367-1", "name": "Small ribosomal subunit protein uS11A", "aln": "MSN--------------VVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. :.. * **.:*:***.***********:***.************:*:************* :.* :****:*:*: ****.:**:****.*:********.::**:*****.:*****::* * ** *", "identical_positions": 92, "similar_positions": 32, "identity": "60.93%" }, { "cls_id": "homologset.agr.FB:FBgn0004406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYV8-1", "uniprot_id": "DPOG1_RAT", "id": "Q9QYV8-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWKKVAGAKVASGPVPATGRWVSSSVLDPVPSDGQ-----------------PQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFG-CGGDVPDEAAVQRS---IEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSEAQLPPQ-PRKWVWAEGWTRYGPE-GEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQQDWQEQ---LVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTK-RGQKSQKNANGPAISSWDWMDISSANNLADVHNLYVGGPRLAKEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLTEAQSTYEELQREMKKSLMELANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKK-TASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLPGHPGWYRKLCPR-----------LDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTELPVSPTEESAAVTCPYRAIESLYRRHCLDQGKQQLETQETDLAEEFLLTD-SAMWQTVEELGCLDVEAEATVE---SSGLSQPLVPPTACAPKTSQPTYHHGNGPYNDVDIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAG-PGGARGPRALEINKMISFWRNAHKRISSQMVV---WLPRSALPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASRKSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPS---VVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKG-SLEKRSQPGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54099-1", "uniprot_id": "DPOG1_MOUSE", "id": "P54099-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWKKVAGAKVASGPVPATARWVASSVLDPVPSDGR-----------------PPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFG-CGGEMPDEAAVQRS---VEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPE-PKSWAWAEGWTRYGPE-GEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTKQDGQEQ---LVVGHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKNPAAHKARAEVPEESQWSSESSSWDWMDISSANNLADVHNLYVGGPPLEKEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLTEAQNTYEELQREMKKSLMDLANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKK-PASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQRSVTAHNRLQQLRSTTDLLPKRPQHLPGHPGWYRQLCPR-----------LDDPAWAPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTEPPVSPTVESAAVTCPYRAIESLYRKHCLEQGKQQLEPQEVDLAEEFLLTDNSAMWQTVEELGCLDVEAEAKME---NSGLSQPLVLPAACAPKSSQPTYHHGNGPYNDVNIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAG-PGGASGPRALEINKMISFWRNAHKRISSQMVV---WLPRSALPRVVTRHPAFDEEGHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKIFNYGRIYGAGQSFAERLLMQFNHRLTRQEAAEKAQQMYAVTKGLRRYRLSADGEWLVKQLNLPVDRTEDGWVSLQDLRMIRREASRKSRWKKWEVAAERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPS---VVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKG-SLEKRSQPGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54098-1", "uniprot_id": "DPOG1_HUMAN", "id": "P54098-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFG-QGGEMPGEAAVRRS---VEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPK-PPAWAWAEGWTRYGPE-GEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQ---LVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLAEAQGTYEELQREMKKSLMDLANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPR-----------LDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAG-PGGASGPRALEINKMISFWRNAHKRISSQMVV---WLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPS---AVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKG-SLEKRSQPGP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27607-1", "uniprot_id": "DPOG1_DROME", "id": "Q27607-1", "name": "DNA polymerase subunit gamma-1, mitochondrial", "aln": "MQFHLIRKYA-SKVSREHYASSSVKIFRRVKPPQKVNKP-----------------KKPENVENGPTEYAENLVKVQMISRNLHAQLFP-QAPRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATPVDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHRLS-VEKLEPLDVDTDSERPHYTTDELIPLGTTGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSLHMCVSGVTSYQRAMLKSKKE----------------------PAAEDLGWLEQSSLNSLVEVHRLYCGGDTLSKEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSN-WERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLD-DQYRQNLWLWDEDWSVQELKLKQPPKRKP-------LP---------TVELKDSGNTPEERRLQ------AKFQHLYDQQALLPARRPLLPGYPLWYRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLHYEREQGWGFLVPFRSD--SEGVDRLPMEQLLAHCPVPEFARLSASKAESDMAFDMLPG-----------------QVEQHLGKREHYKKLSQK------------------QQRLETQYQGSGVWCNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSGDPSCQAAARVIDIARMMSYWRNNRDRIMGQMVV---WLDSQQLPNEFTGEKCQP--IAYGAICPQVVACGTLTRRAMEPTWMTASNSRPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRLR--EEFHDELEDRAYSSYEASRLAIQRNRTLAEVFHRPN------------WQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLMGS---HVRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEVDTVLRKECTMDCKTPSNPHGLRIGYGIQPGQSLSVAEAIEKAGGNDVSQWDWIKKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15801-1", "uniprot_id": "DPOG_YEAST", "id": "P15801-1", "name": "DNA polymerase gamma", "aln": "MTKLMVRSECMLRMVRRRPLRVQFCARWFSTKKNTAEAP------------------------------RINPVGIQYLGESLQRQVFGSCGGKDEVEQSDKLMELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCEDKFTEMVARP--AEWLRKPGWVKYVPG-MAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCSP-----------------FICGGDDPAALIPLNTLNKEQ---VIIGHNVAYDRARVLEEYNFRDSKAFFLDTQSLHIASFGLCSRQRPMFMKNNKKK-------EAEVESEVHPEISIEDYDDPWLNVSALNSLKDVAKFHCKID-LDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIVLLKDKPDFYLKDPWLSQLDWTTKPLRLTKKG---------------------------------------------------------VPAKCQKLPGFPEWYRQLFPS----------------KDTVEPKITIKSRIIPILFKLSWENSPVIWSKESGWCFNVP------HEQVETYKAKNYVLADSVSQEEEEIRTHNLG--------------------------------------------------------------------------------LQCTGVLFKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSE---SELAHQALQINSSGSYWMSARERIQSQFVVPSCKFPNEFQSLSAKSSLNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASNAKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFN-VHGGTAIGWMCLEGTKNEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKLYENTKG----------------------KTKRSKLFKK------------------------FWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKN--LRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELPQNCAFFSQVDIDSVIRKEVNMDCITPSNKTAIPHGEALDINQLLDKSNSKLGKPNLDIDSKVSQYAYNYREPVFEEYNKSYTPEFLKYFLAMQVQSDKRDVNRLEDEYLRECTSKEYARDGNTAEYSLLDYIKDVEKGKRTKVRIMGSNFLDGTKNAKADQRIRLPVNMPDYPTLHKIANDSAIPEKQLLENRRKKENRIDDENKKKLTRKKNTTPMERKYKRVYGGRKAFEAFYECANKPLDYTLETEKQFFNIPIDGVIDDVLNDKSNYKKKPSQARTASSSPIRKTAKAVHSKKLPARKSSTTNRNLVELERDITISREY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :. . : : * : :* :...*: *:* . * . *: **: : : :.: ** * * .:::**: :.: : ** . * **. * * . * * *. :*****. . *.**.*:*.. ** * * . . :::****::***:: *:* ..: *:** *:*:. *: * **.: :: . *:: *: *.* :* .:: * * *::*.. : :.**.* :*** ** ** .:: *:: :: ***.::**: .:. . **.: * *: *: .:: *:: . : : : :: * : * :: ** : :* : :: .: :* : ***.* ***:* . . :: :: * *: * *:. *: :. ** : ** : :. . : ::*:** :* . . . ::*.: : ...*.: . :.::* *:* . :.** .*:** : . . . * *::*. **:****:* :*:****::.:*:****:: *:***** :*******:*****:::**: ** *.:*** *.* *..*:*:*: ** :* **:.**::**.****** **. ** :** :: .*: * ::: *** : . : : * **:** :**:**.** . *:**.** :: :* . *:.:*:**.:**..**:***: :*.::: . . *:*:*:***:*:** *: :**:*::*:*: **.: ::*:::** . **** *::* :*** .*** **** .: .: .: *. : . .:.. ", "identical_positions": 270, "similar_positions": 291, "identity": "17.69%" }, { "cls_id": "homologset.agr.FB:FBgn0004407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYP7-1", "uniprot_id": "D3ZYP7_RAT", "id": "D3ZYP7-1", "name": "DNA polymerase subunit gamma-2", "aln": "MHSGGVARACRRACRCWLSGYAGPTDGTQ--------------------------QPTDPEHALAREALVDLCRRRHFLSGTPQQLSTAALLSGCHSGFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHHEPGSSQPRDSAFRLVSPECIREILQDKELSKEQLVAFLENLLKTSGKLRETLLHGALEHYVHCLDLVNRKLPYGLAQIGVCFHPVLNPKEIPNSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAVSPSNFSSVDCQDGSGRKGCRLYYSFPWGKEPLETLWDLGEQELLNVYPGDVSAIQGRDGRKNVVPSVLSVNGDLDLGTLAYLYDSFQFTENSFSRKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGIAVWPG---YLETAQSSLEQLYSKYDEMSILFTVLITETTLESGLIQLRSRDTTMKEMMHISRLRDFLVKYLASAGKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZM2-1", "uniprot_id": "DPOG2_MOUSE", "id": "Q9QZM2-1", "name": "DNA polymerase subunit gamma-2", "aln": "MRCGGGARACRRACRCWLSGYAGPADGTQ--------------------------QPDAPEHAVAREALVDLCRRRHFFSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSFARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVWPG---YSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHN1-1", "uniprot_id": "DPOG2_HUMAN", "id": "Q9UHN1-1", "name": "DNA polymerase subunit gamma-2", "aln": "MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPG---YLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJV8-1", "uniprot_id": "DPOG2_DROME", "id": "Q9VJV8-1", "name": "DNA polymerase subunit gamma-2, mitochondrial", "aln": "---------MSRIQRCFKS--------------------------------------------LASAGFFRTVED-NKLELLSHGREYAKLLQQHWTRLRPLAAHLG------------ATKEPINPVNIQRFS----FPQSQQFRNN----FQKLVKDHP-RKAKCPTLLKHQSTCSGPTSNSLFG------------------------------------------IKGPTLHLTTDFLVEPHRALEHFYNMQRESKIWWMRLSSNPSRYRIVPCDLAEDLNPNDYQAIDIRTSYGDAGEVTVEQLSLVRIVDDKDFRLPDARTGEIVQPTVIRSVIELETTTCALLLDGCDHGRDSQS---LLLHRVLAPYQCG---IACVESDSELSADLSDLCQHLKHVLNHAGLRLSEGDGIRTTKNASHLAEHLLETDMLGIPYTLVINEQTLRNGLMQLRSRDTRLAETIHISDVPDYLLNIFKN----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** * . .:. . : :. : . **. . : **...* . :* : .*: : . * .. ** ::::::*: * : ::*:: . ** .*: * . . : ::. .: : : : *. ** ::: .**.: *: . : . : : .*:. .. : . : * * *: ::: * * *. : .:* : * ::** : * ..:: . : :* ::** * : * . *: : * . * * : : * :.: :::::.* **..**::****** : * :*** : *:*:: : . ", "identical_positions": 65, "similar_positions": 122, "identity": "13.32%" }, { "cls_id": "homologset.agr.FB:FBgn0004419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54823-1", "uniprot_id": "DDX6_MOUSE", "id": "P54823-1", "name": "Probable ATP-dependent RNA helicase DDX6", "aln": "MSTARTENPV-IMGLSSQNGQLRGPVKASAGPGGGGTQPQP-QLNQLKNTSTINNGTPQQAQSMAATIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPAE----DEKP----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD73-1", "uniprot_id": "D3ZD73_RAT", "id": "D3ZD73-1", "name": "Probable ATP-dependent RNA helicase DDX6", "aln": "MSTARTENPV-IMGLSSQNGQLRGPVKASAGPGGGGPQTQT-QMNQLKNTSTINNGTQQQAQSMAATIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPAE----DEKP----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26196-1", "uniprot_id": "DDX6_HUMAN", "id": "P26196-1", "name": "Probable ATP-dependent RNA helicase DDX6", "aln": "MSTARTENPV-IMGLSSQNGQLRGPVKPTGGPGGGGTQTQQ-QMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVE----DEKP----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FD91-1", "uniprot_id": "E7FD91_DANRE", "id": "E7FD91-1", "name": "RNA helicase", "aln": "MSTARMENPV-ILGLSNQNGQMRGSVKPAGGPGGGGGGSQTTQPAQVKASSTVNNGNSQPVPTANTIIKPGDDWKKNLKLPPKDLRMKTSDVTATKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERIDLKKDSIQAVVIVPTRELALQVSQICIQVSKHMGGVKVMATTGGTNLRDDIMRLDETVHVVIATPGRILDLIKKGVAKVGQVQMIVLDEADKLLSQDFVQMMEEILSSLSKQRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLGETYLHRIGRSGRFGHLGLAINLITYDDRFNLKGIEEQLGTEIKPIPSSIDKSLYVAEYHSESGE----EVKL----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1G8-1", "uniprot_id": "E7F1G8_DANRE", "id": "E7F1G8-1", "name": "RNA helicase", "aln": "MATARTEIPASVMPVTKQNGQAKPMSLQTGSFSSSTPSGKTPVMPQKGSSIPQSSGG----------IRFGDDWKKCLQLPPKDTRVRTTDVTATKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERIDLKKDYIQAIVLVPTRELALQVSQISINMSKHLGGIKVMATTGGTNLRDDIMRLDEIVHVIIATPGRILDLIKKGVAKVDKVQMAVMDEADKLLSQDFVVLIEDIISFLPKKRQILLYSATFPISVQKFMTKHLQKPYEINLMDELTLKGITQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSTQRVELLAKKITQLGYSCFYIHAKMMQEYRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRYGHLGLAINLITSEDRFNLKGIEDQLMTDIKPIPSSIDKSLYVAEFHSMNPD----EEEAAHKTGELN--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23128-1", "uniprot_id": "DDX6_DROME", "id": "P23128-1", "name": "ATP-dependent RNA helicase me31b", "aln": "-----------MMTEKLNSGHTNLTSKGIIN------------DLQIAGNTSDDMG-----------------WKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQTSQICIELAKHLD-IRVMVTTGGTILKDDILRIYQKVQLIIATPGRILDLMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINLMEELTLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLHRIGRSGRFGHLGIAINLITYEDRFDLHRIEKELGTEIKPIPKVIDPALYVANVGASVGD----TCNNSDLNNSANEEGNVSK-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39517-1", "uniprot_id": "DHH1_YEAST", "id": "P39517-1", "name": "ATP-dependent RNA helicase DHH1", "aln": "------------MGSINNNFNTN-----------------------NNSNTDLDR-----------------DWKTALNIPKKDTRPQTDDVLNTKGNTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLEKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCG-ISCMVTTGGTNLRDDILRLNETVHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFSATFPLTVKEFMVKHLHKPYEINLMEELTLKGITQYYAFVEERQKLHCLNTLFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGTEIAAIPATIDKSLYVAENDETVPVPFPIEQQSYHQQAIPQQQLPSQQQFAIPPQQHHPQFMVPPSHQQQQAYPPPQMPSQQGYPPQQEHFMAMPPGQSQPQY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : . . . **. *::* ** * :* ** *:** **:: *********** *:*:****** :**:*::*:*:**********:.*: ** **::. . : ***:::*********.**: :.** . *.***** *:***:*: : *::::.****:*** .: **.:.. : ::*****:** ** :::.:: *. * **:*****::*::** .**::*******:******:*****:* ****:********:*****:******::*********::***.*:* **:* * **:***:**:* *.***:**:*****:************: .************:****:*****. :***:* **.:* *:* .** ** :****: : ", "identical_positions": 243, "similar_positions": 108, "identity": "43.47%" }, { "cls_id": "homologset.agr.FB:FBgn0004425", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08905-1", "uniprot_id": "LYZ2_MOUSE", "id": "P08905-1", "name": "Lysozyme C-2", "aln": "--MKTL---LTLGLLLLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17897-1", "uniprot_id": "LYZ1_MOUSE", "id": "P17897-1", "name": "Lysozyme C-1", "aln": "--MKAL---LTLGLLLLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQYIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00697-1", "uniprot_id": "LYSC1_RAT", "id": "P00697-1", "name": "Lysozyme C-1", "aln": "--MKAL---LVLGFLLLSASVQAKIYERCQFARTLKRNGMSGYYGVSLADWVCLAQHESNYNTQARNYNPGDQSTDYGIFQINSRYWCNDGKTPRAKNACGIPCS------ALLQDDITQAIQCAKRVVRDPQGIRAWVAWQRHCKNRDLSGYIRNCGV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61626-1", "uniprot_id": "LYSC_HUMAN", "id": "P61626-1", "name": "Lysozyme C", "aln": "--MKAL---IVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCS------ALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0W2-1", "uniprot_id": "D4A0W2_RAT", "id": "D4A0W2-1", "name": "", "aln": "--MKALPTLLTLGLLLLSITVQGKVLNRCLLARTLQRFGLGGFKGISLANWICLAKSVSGYDTKAIKYNHEDRSTNYGIFQISSRYWCNDSKTPGSKNFCRVSCK------ALLKNNIKASVTCAKRIVKDPRGITTWEAWRKNCEHKNLFQYVQGCSL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AE20-1", "uniprot_id": "LYZL5_MOUSE", "id": "A2AE20-1", "name": "Sperm acrosome-associated protein 5", "aln": "MKVCSI--VVVILAVLLIAKLDAKIYERCELAKKLEEAGLDGFKGYTVGDWLCVAHYESGFDTSFVDHNP-DGSSEYGIFQLNSAWWCN-NGITPTQNLCNIDCN------DLLNRHILDDIICAKRVASSHKSMKAWDSWTQHCAGHDLSEWLKGCSVRLKTDSSYNNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DA11-1", "uniprot_id": "LYZL6_MOUSE", "id": "Q9DA11-1", "name": "Lysozyme-like protein 6", "aln": "-MLKAL--FICVASCLLVVN-DGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVNENV-DGSFDYGIFQINSRYWCN-DYQSHSENFCHVDCQ------ELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSYWMTGCHLG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CPX3-1", "uniprot_id": "LYZL1_MOUSE", "id": "Q9CPX3-1", "name": "Lysozyme-like protein 1", "aln": "MKSVGV--FALIISFSIVAE--SKIYTRCKLAKIFAKAGLDNYGGFALGNWLCMAYYESHYNTTAENVLE-DGSTDYGIFQINSFTWCR-NARKHQKNHCHVACS------ALITDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSEWKRGCEVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08694-1", "uniprot_id": "LYSB_DROME", "id": "Q08694-1", "name": "Lysozyme B", "aln": "--MKAF--IVLVALALAAP-ALGRTMDRCSLAREMS--NLG-VPRDQLARWACIAEHESSYRTGVVGPENYNGSNDYGIFQINDYYWCAPPSGRFSYNECGLSCN------ALLTDDITHSVRCAQKVLS-QQGWSAWSTWHYCSGWLPSIDDCF---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00709-1", "uniprot_id": "LALBA_HUMAN", "id": "P00709-1", "name": "Alpha-lactalbumin", "aln": "--MRFF--VPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQAIVEN--NESTEYGLFQISNKLWCKSSQVPQSRNICDISCD------KFLDDDITDDIMCAKKILD-IKGIDYWLAHKALCTEKLEQWLCEKL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5Y928-1", "uniprot_id": "A0A8I5Y928_RAT", "id": "A0A8I5Y928-1", "name": "lysozyme", "aln": "--MKAL---LVLGFLLLSASVQAKVFKHCELARILRSSALAGYRGVSLENWMCMAQHESNFDTEAINYNSTDQSTDYGIFQINSRYWCNDGKTPRAVNACGIPCSGKTRRVTVAANKPSALTARAETLCRRQTLGEASGAWGDCFTVRVAVNYIKISQLRH---------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. :* ::: : : : * * : : * :**:**:.. ** * * : *. . . *: : ", "identical_positions": 14, "similar_positions": 24, "identity": "8.24%" }, { "cls_id": "homologset.agr.FB:FBgn0004427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08905-1", "uniprot_id": "LYZ2_MOUSE", "id": "P08905-1", "name": "Lysozyme C-2", "aln": "--MKTLLTLGLL-LLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17897-1", "uniprot_id": "LYZ1_MOUSE", "id": "P17897-1", "name": "Lysozyme C-1", "aln": "--MKALLTLGLL-LLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQYIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61626-1", "uniprot_id": "LYSC_HUMAN", "id": "P61626-1", "name": "Lysozyme C", "aln": "--MKALIVLGLV-LLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCS------ALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5Y928-1", "uniprot_id": "A0A8I5Y928_RAT", "id": "A0A8I5Y928-1", "name": "lysozyme", "aln": "--MKALLVLGFL-LLSASVQAKVFKHCELARILRSSALAGYRGVSLENWMCMAQHESNFDTEAINYNSTDQSTDYGIFQINSRYWCNDGKTPRAVNACGIPCSGKTRRVTVAANKPSALTARAETLCRRQTLGEASGAWGDCFTVRVAVNYIKISQLRH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AE20-1", "uniprot_id": "LYZL5_MOUSE", "id": "A2AE20-1", "name": "Sperm acrosome-associated protein 5", "aln": "MKVCSIVVVILAVLLIAKLDAKIYERCELAKKLEEAGLDGFKGYTVGDWLCVAHYESGFDTSFVDH-NPDGSSEYGIFQLNSAWWCNNGITP-TQNLCNIDCN------DLLNRHILDDIICAKRVASSHKSMKAWDSWTQHCAGHDLSEWLKGCSVRLKTDSSYNNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QH8-1", "uniprot_id": "LYZL5_HUMAN", "id": "Q96QH8-1", "name": "Sperm acrosome-associated protein 5", "aln": "MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDH-NPDGSSEYGIFQLNSAWWCDNGITP-TKNLCHMDCH------DLLNRHILDDIRCAKQIVSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DA11-1", "uniprot_id": "LYZL6_MOUSE", "id": "Q9DA11-1", "name": "Lysozyme-like protein 6", "aln": "--MLKALFICVASCLLVVNDGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVNE-NVDGSFDYGIFQINSRYWCNDYQSH-SENFCHVDCQ------ELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSYWMTGCHLG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75951-1", "uniprot_id": "LYZL6_HUMAN", "id": "O75951-1", "name": "Lysozyme-like protein 6", "aln": "--MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKINE-NADGSFDYGLFQINSHYWCNDYKSY-SENLCHVDCQ------DLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPX3-1", "uniprot_id": "LYZL1_MOUSE", "id": "Q9CPX3-1", "name": "Lysozyme-like protein 1", "aln": "--MKSVGVFALIISFSIVAESKIYTRCKLAKIFAKAGLDNYGGFALGNWLCMAYYESHYNTTAENV-LEDGSTDYGIFQINSFTWCRNARKH-QKNHCHVACS------ALITDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSEWKRGCEVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWQ5-1", "uniprot_id": "LYZL1_HUMAN", "id": "Q6UWQ5-1", "name": "Lysozyme-like protein 1", "aln": "--MKAAGILTLIGCLVTGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTV-LDDGSIDYGIFQINSFAWCRRGKLK-ENNHCHVACS------ALITDDLTDAIICARKIVKETQGMNYWQGWKKHCEGRDLSEWKKGCEVS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00709-1", "uniprot_id": "LALBA_HUMAN", "id": "P00709-1", "name": "Alpha-lactalbumin", "aln": "--MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQAIVE-NNE-STEYGLFQISNKLWCKSSQVPQSRNICDISCD------KFLDDDITDDIMCAKKILD-IKGIDYWLAHKALCTEK-LEQWLCEKL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83972-1", "uniprot_id": "LYSD_DROME", "id": "P83972-1", "name": "Lysozyme D", "aln": "--MKAFIVLVALACAAPAFG-RTMDRCSLAREMSNLGVPRDQ---LARWACIAEHESSYRTGVVGPENYNGSNDYGIFQINDYYWCAPPSGRFSYNECGLSCN------ALLTDDITHSVRCAQKVLS----QQGWSAWSTWHYCSGWLPSIDDCF------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*.:: : : : * * : : * :**:**:.. ** * * : * . . *. : ", "identical_positions": 14, "similar_positions": 20, "identity": "8.33%" }, { "cls_id": "homologset.agr.FB:FBgn0004428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08905-1", "uniprot_id": "LYZ2_MOUSE", "id": "P08905-1", "name": "Lysozyme C-2", "aln": "--------------------------------------------------MKTLLTLG-------------------------LLLLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCS-----ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQ-YIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17897-1", "uniprot_id": "LYZ1_MOUSE", "id": "P17897-1", "name": "Lysozyme C-1", "aln": "--------------------------------------------------MKALLTLG-------------------------LLLLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCS-----ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQ-YIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00697-1", "uniprot_id": "LYSC1_RAT", "id": "P00697-1", "name": "Lysozyme C-1", "aln": "--------------------------------------------------MKALLVLG-------------------------FLLLSASVQAKIYERCQFARTLKRNGMSGYYGVSLADWVCLAQHESNYNTQARNYNPGDQSTDYGIFQINSRYWCNDGKTPRAKNACGIPCS-----ALLQDDITQAIQCAKRVVRDPQGIRAWVAWQRHCKNRDLSG-YIRNCGV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61626-1", "uniprot_id": "LYSC_HUMAN", "id": "P61626-1", "name": "Lysozyme C", "aln": "--------------------------------------------------MKALIVLG-------------------------LVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCS-----ALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQ-YVQGCGV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D925-1", "uniprot_id": "LYZL4_MOUSE", "id": "Q9D925-1", "name": "Lysozyme-like protein 4", "aln": "--------------------------------------------------MQLYLVL------------------------LLISYLLTPIGASILGRCTVAKMLYDGGLNYFEGYSLENWVCLAYFESKFNPSAVYEDPQDGSTGFGLFQIRDNEWCG-----HGKNLCSVSCT-----ALLNPNLKDTIQCAKKIVKGKHGMGAWPIWSKNCQLSDVLDRWLDGCDL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9D9X8-1", "uniprot_id": "SACA3_MOUSE", "id": "Q9D9X8-1", "name": "Sperm acrosome membrane-associated protein 3", "aln": "MGICMSMYTQVLVPVDADGDHHILWSRFYERWGSCFNPCAGLVNCLPPHSSALYLCHRMEARSRAPRRQLCPPGITWLALAYLLSCLLASSKAKVFSRCELAKEMHDFGLDGYRGYNLADWVCLAYYTSGFNTNAVDHEA-DGSTNNGIFQISSRRWCRTLA-SNGPNLCRIYCT-----DLLNNDLKDSIVCAMKIVQEPLGLGYWEAWRHHCQGRDLSD-WVDGCDF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DA11-1", "uniprot_id": "LYZL6_MOUSE", "id": "Q9DA11-1", "name": "Lysozyme-like protein 6", "aln": "------------------------------------------------MLKALFICV--------------------------ASCLLVVNDGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVNENV-DGSFDYGIFQINSRYWCNDYQ-SHSENFCHVDCQ-----ELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSY-WMTGCHLG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AE20-1", "uniprot_id": "LYZL5_MOUSE", "id": "A2AE20-1", "name": "Sperm acrosome-associated protein 5", "aln": "-----------------------------------------------MKVCSIVVVI-------------------------LAVLLIAKLDAKIYERCELAKKLEEAGLDGFKGYTVGDWLCVAHYESGFDTSFVDHNP-DGSSEYGIFQLNSAWWCNNGI-TPTQNLCNIDCN-----DLLNRHILDDIICAKRVASSHKSMKAWDSWTQHCAGHDLSE-WLKGCSVRLKTDSSYNNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CPX3-1", "uniprot_id": "LYZL1_MOUSE", "id": "Q9CPX3-1", "name": "Lysozyme-like protein 1", "aln": "-----------------------------------------------MKSVGVFA---------------------------LIISFSIVAESKIYTRCKLAKIFAKAGLDNYGGFALGNWLCMAYYESHYNTTAENVLE-DGSTDYGIFQINSFTWCRNAR-KHQKNHCHVACS-----ALITDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSE-WKRGCEVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37159-1", "uniprot_id": "LYSE_DROME", "id": "P37159-1", "name": "Lysozyme E", "aln": "--------------------------------------------------MKAFIVL------------------------VALAMAAP-ALGRTLDRCSLAREMS--NLG-VPRDQLARWACIAEHESSYRTGVVGPENYNGSNDYGIFQINNYYWCAPPSGRFSYNECGLSCN-----ALLTDDITHSVRCAQKVLS-QQGWSAWSTWHYCSGWLPSID----GCF------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00709-1", "uniprot_id": "LALBA_HUMAN", "id": "P00709-1", "name": "Alpha-lactalbumin", "aln": "--------------------------------------------------MRFFVPL------------------------FLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQAIVEN--NESTEYGLFQISNKLWCKSSQVPQSRNICDISCD-----KFLDDDITDDIMCAKKILD-IKGIDYWLAHKALCTEKLEQW----LCEKL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0W2-1", "uniprot_id": "D4A0W2_RAT", "id": "D4A0W2-1", "name": "", "aln": "-----------------------------------------------MKALPTLLTLG-------------------------LLLLSITVQGKVLNRCLLARTLQRFGLGGFKGISLANWICLAKSVSGYDTKAIKYNHEDRSTNYGIFQISSRYWCNDSKTPGSKNFCRVSCK-----ALLKNNIKASVTCAKRIVKDPRGITTWEAWRKNCEHKNLFQ-YVQGCSL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y928-1", "uniprot_id": "A0A8I5Y928_RAT", "id": "A0A8I5Y928-1", "name": "lysozyme", "aln": "--------------------------------------------------MKALLVLG-------------------------FLLLSASVQAKVFKHCELARILRSSALAGYRGVSLENWMCMAQHESNFDTEAINYNSTDQSTDYGIFQINSRYWCNDGKTPRAVNACGIPCSGKTRRVTVAANKPSALTARAETLCRRQTLGEASGAWGDCFTVRVAVNYIKISQLRH---------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* .:: : : : * * : : * *:**: . ** * * : * : . : . . . . ", "identical_positions": 12, "similar_positions": 21, "identity": "5.0%" }, { "cls_id": "homologset.agr.FB:FBgn0004429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08905-1", "uniprot_id": "LYZ2_MOUSE", "id": "P08905-1", "name": "Lysozyme C-2", "aln": "MKTL---LTLGLLLLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17897-1", "uniprot_id": "LYZ1_MOUSE", "id": "P17897-1", "name": "Lysozyme C-1", "aln": "MKAL---LTLGLLLLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQYIRNCGV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00697-1", "uniprot_id": "LYSC1_RAT", "id": "P00697-1", "name": "Lysozyme C-1", "aln": "MKAL---LVLGFLLLSASVQAKIYERCQFARTLKRNGMSGYYGVSLADWVCLAQHESNYNTQARNYNPGDQSTDYGIFQINSRYWCNDGKTPRAKNACGIPCS------ALLQDDITQAIQCAKRVVRDPQGIRAWVAWQRHCKNRDLSGYIRNCGV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61626-1", "uniprot_id": "LYSC_HUMAN", "id": "P61626-1", "name": "Lysozyme C", "aln": "MKAL---IVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCS------ALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0W2-1", "uniprot_id": "D4A0W2_RAT", "id": "D4A0W2-1", "name": "", "aln": "MKALPTLLTLGLLLLSITVQGKVLNRCLLARTLQRFGLGGFKGISLANWICLAKSVSGYDTKAIKYNHEDRSTNYGIFQISSRYWCNDSKTPGSKNFCRVSCK------ALLKNNIKASVTCAKRIVKDPRGITTWEAWRKNCEHKNLFQYVQGCSL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y928-1", "uniprot_id": "A0A8I5Y928_RAT", "id": "A0A8I5Y928-1", "name": "lysozyme", "aln": "MKAL---LVLGFLLLSASVQAKVFKHCELARILRSSALAGYRGVSLENWMCMAQHESNFDTEAINYNSTDQSTDYGIFQINSRYWCNDGKTPRAVNACGIPCSGKTRRVTVAANKPSALTARAETLCRRQTLGEASGAWGDCFTVRVAVNYIKISQLRH-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29615-1", "uniprot_id": "LYSP_DROME", "id": "P29615-1", "name": "Lysozyme P", "aln": "MKAF--LVICALTLTAVATQARTMDRCSLAREMSKLGVPRDQ---LAKWTCIAQHESSFRTGVVGPANSNGSNDYGIFQINNKYWCKPADGRFSYNECGLSCN------ALLTDDITNSVKCARKIQR-QQGWTAWSTWKYCSG---SLPSINSCF----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00714-1", "uniprot_id": "LALBA_RAT", "id": "P00714-1", "name": "Alpha-lactalbumin", "aln": "MMRFVP-LFLACIS-LPAFQATEFTKCEVSHAIED--MDGYQGISLLEWTCVLFHTSGYDSQAIVKN--NGSTEYGLFQISNRNWCKSSEFPESENICDISCD------KFLDDELADDIVCAKKIVA-IKGIDYWKAHKPMCSEKLEQWRCEKPGAPALVVPALNSETPVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29752-1", "uniprot_id": "LALBA_MOUSE", "id": "P29752-1", "name": "Alpha-lactalbumin", "aln": "MMHFVP-LFLVCILSLPAFQATELTKCKVSHAIKD--IDGYQGISLLEWACVLFHTSGYDTQAVVND--NGSTEYGLFQISDRFWCKSSEFPESENICGISCD------KLLDDELDDDIACAKKILA-IKGIDYWKAYKPMCSEKLEQWRCEKP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00709-1", "uniprot_id": "LALBA_HUMAN", "id": "P00709-1", "name": "Alpha-lactalbumin", "aln": "MRFFVP-LFLVGIL-FPAILAKQFTKCELSQLLKD--IDGYGGIALPELICTMFHTSGYDTQAIVEN--NESTEYGLFQISNKLWCKSSQVPQSRNICDISCD------KFLDDDITDDIMCAKKILD-IKGIDYWLAHKALCTEKLEQWLCEKL-----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : : . :* .:: : : * . * *.: : . : *.:**:***..: **: .. : * * : *. . :. *. : : . ", "identical_positions": 17, "similar_positions": 35, "identity": "9.88%" }, { "cls_id": "homologset.agr.FB:FBgn0004430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08905-1", "uniprot_id": "LYZ2_MOUSE", "id": "P08905-1", "name": "Lysozyme C-2", "aln": "MKTL---LTLGLLLLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17897-1", "uniprot_id": "LYZ1_MOUSE", "id": "P17897-1", "name": "Lysozyme C-1", "aln": "MKAL---LTLGLLLLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQYIRNCGV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00697-1", "uniprot_id": "LYSC1_RAT", "id": "P00697-1", "name": "Lysozyme C-1", "aln": "MKAL---LVLGFLLLSASVQAKIYERCQFARTLKRNGMSGYYGVSLADWVCLAQHESNYNTQARNYNPGDQSTDYGIFQINSRYWCNDGKTPRAKNACGIPCS------ALLQDDITQAIQCAKRVVRDPQGIRAWVAWQRHCKNRDLSGYIRNCGV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61626-1", "uniprot_id": "LYSC_HUMAN", "id": "P61626-1", "name": "Lysozyme C", "aln": "MKAL---IVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCS------ALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0W2-1", "uniprot_id": "D4A0W2_RAT", "id": "D4A0W2-1", "name": "", "aln": "MKALPTLLTLGLLLLSITVQGKVLNRCLLARTLQRFGLGGFKGISLANWICLAKSVSGYDTKAIKYNHEDRSTNYGIFQISSRYWCNDSKTPGSKNFCRVSCK------ALLKNNIKASVTCAKRIVKDPRGITTWEAWRKNCEHKNLFQYVQGCSL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AE20-1", "uniprot_id": "LYZL5_MOUSE", "id": "A2AE20-1", "name": "Sperm acrosome-associated protein 5", "aln": "MKVCSIVVVILAVLLIAKLDAKIYERCELAKKLEEAGLDGFKGYTVGDWLCVAHYESGFDTSFVDHNP-DGSSEYGIFQLNSAWWCN-NGITPTQNLCNIDCN------DLLNRHILDDIICAKRVASSHKSMKAWDSWTQHCAGHDLSEWLKGCSVRLKTDSSYNNW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DA11-1", "uniprot_id": "LYZL6_MOUSE", "id": "Q9DA11-1", "name": "Lysozyme-like protein 6", "aln": "-MLKALFICVASCLLVVN-DGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVNENV-DGSFDYGIFQINSRYWCN-DYQSHSENFCHVDCQ------ELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSYWMTGCHLG--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CPX3-1", "uniprot_id": "LYZL1_MOUSE", "id": "Q9CPX3-1", "name": "Lysozyme-like protein 1", "aln": "MKSVGVFALIISFSIVAE--SKIYTRCKLAKIFAKAGLDNYGGFALGNWLCMAYYESHYNTTAENVLE-DGSTDYGIFQINSFTWCR-NARKHQKNHCHVACS------ALITDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSEWKRGCEVS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00714-1", "uniprot_id": "LALBA_RAT", "id": "P00714-1", "name": "Alpha-lactalbumin", "aln": "-MMRFVPLFLACIS-LPAFQATEFTKCEVSHAIE--DMDGYQGISLLEWTCVLFHTSGYDSQAIVKNN--GSTEYGLFQISNRNWCKSSEFPESENICDISCD------KFLDDELADDIVCAKKIVA-IKGIDYWKAHKPMCSEKLEQWRCEKPGAPALVVPALNSETPVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29752-1", "uniprot_id": "LALBA_MOUSE", "id": "P29752-1", "name": "Alpha-lactalbumin", "aln": "-MMHFVPLFLVCILSLPAFQATELTKCKVSHAIK--DIDGYQGISLLEWACVLFHTSGYDTQAVVNDN--GSTEYGLFQISDRFWCKSSEFPESENICGISCD------KLLDDELDDDIACAKKILA-IKGIDYWKAYKPMCSEKLEQWRCEKP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00709-1", "uniprot_id": "LALBA_HUMAN", "id": "P00709-1", "name": "Alpha-lactalbumin", "aln": "-MRFFVPLFLVGIL-FPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQAIVENN--ESTEYGLFQISNKLWCKSSQVPQSRNICDISCD------KFLDDDITDDIMCAKKILD-IKGIDYWLAHKALCTEKLEQWLCEKL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37160-1", "uniprot_id": "LYSS_DROME", "id": "P37160-1", "name": "Lysozyme S", "aln": "-MKAFFALVLLAIA-APALAGRTLDRCSLAREMA--DLG-VPRDQLDKWTCIAQHESDYRTWVVGPANSDGSNDYGIFQINDLYWCQADGR-FSYNECGLSCN------ALLTDDITNSVRCAQKVLS-QQGWSAWAVWHYCSGWLPSIDECF-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I5Y928-1", "uniprot_id": "A0A8I5Y928_RAT", "id": "A0A8I5Y928-1", "name": "lysozyme", "aln": "---MKALLVLGFLLLSASVQAKVFKHCELARILRSSALAGYRGVSLENWMCMAQHESNFDTEAINYNSTDQSTDYGIFQINSRYWCNDGKTPRAVNACGIPCSGKTRRVTVAANKPSALTARAETLCRRQTLGEASGAWGDCFTVRVAVNYIKISQLRH-------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* .:: : : : . * * : * :**:**:.. **. . * * : *. . . *: : ", "identical_positions": 14, "similar_positions": 24, "identity": "8.14%" }, { "cls_id": "homologset.agr.FB:FBgn0004431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08905-1", "uniprot_id": "LYZ2_MOUSE", "id": "P08905-1", "name": "Lysozyme C-2", "aln": "--MKTL---LTLGLLLLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17897-1", "uniprot_id": "LYZ1_MOUSE", "id": "P17897-1", "name": "Lysozyme C-1", "aln": "--MKAL---LTLGLLLLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCS------ALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQYIRNCGV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00697-1", "uniprot_id": "LYSC1_RAT", "id": "P00697-1", "name": "Lysozyme C-1", "aln": "--MKAL---LVLGFLLLSASVQAKIYERCQFARTLKRNGMSGYYGVSLADWVCLAQHESNYNTQARNYNPGDQSTDYGIFQINSRYWCNDGKTPRAKNACGIPCS------ALLQDDITQAIQCAKRVVRDPQGIRAWVAWQRHCKNRDLSGYIRNCGV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61626-1", "uniprot_id": "LYSC_HUMAN", "id": "P61626-1", "name": "Lysozyme C", "aln": "--MKAL---IVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCS------ALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5Y928-1", "uniprot_id": "A0A8I5Y928_RAT", "id": "A0A8I5Y928-1", "name": "lysozyme", "aln": "--MKAL---LVLGFLLLSASVQAKVFKHCELARILRSSALAGYRGVSLENWMCMAQHESNFDTEAINYNSTDQSTDYGIFQINSRYWCNDGKTPRAVNACGIPCSGKTRRVTVAANKPSALTARAETLCRRQTLGEASGAWGDCFTVRVAVNYIKISQLRH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A0W2-1", "uniprot_id": "D4A0W2_RAT", "id": "D4A0W2-1", "name": "", "aln": "--MKALPTLLTLGLLLLSITVQGKVLNRCLLARTLQRFGLGGFKGISLANWICLAKSVSGYDTKAIKYNHEDRSTNYGIFQISSRYWCNDSKTPGSKNFCRVSCK------ALLKNNIKASVTCAKRIVKDPRGITTWEAWRKNCEHKNLFQYVQGCSL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AE20-1", "uniprot_id": "LYZL5_MOUSE", "id": "A2AE20-1", "name": "Sperm acrosome-associated protein 5", "aln": "MKVCSIV--VVILAVLLIAKLDAKIYERCELAKKLEEAGLDGFKGYTVGDWLCVAHYESGFDTSFVD-HNPDGSSEYGIFQLNSAWWCN-NGITPTQNLCNIDCN------DLLNRHILDDIICAKRVASSHKSMKAWDSWTQHCAGHDLSEWLKGCSVRLKTDSSYNNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QH8-1", "uniprot_id": "LYZL5_HUMAN", "id": "Q96QH8-1", "name": "Sperm acrosome-associated protein 5", "aln": "MKAWGTV--VVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVD-HNPDGSSEYGIFQLNSAWWCD-NGITPTKNLCHMDCH------DLLNRHILDDIRCAKQIVSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DA11-1", "uniprot_id": "LYZL6_MOUSE", "id": "Q9DA11-1", "name": "Lysozyme-like protein 6", "aln": "--MLKAL--FICVASCLLVVNDGNIIHRCSLAKILYEEDLDGFEGYSLPDWLCLAFVESNFNISKVN-ENVDGSFDYGIFQINSRYWCN-DYQSHSENFCHVDCQ------ELLSPNLISTIHCAKKIVSGPGGMKNWVEWKLHCLGRPLSYWMTGCHLG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75951-1", "uniprot_id": "LYZL6_HUMAN", "id": "O75951-1", "name": "Lysozyme-like protein 6", "aln": "--MTKAL--LIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKIN-ENADGSFDYGLFQINSHYWCN-DYKSYSENLCHVDCQ------DLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPX3-1", "uniprot_id": "LYZL1_MOUSE", "id": "Q9CPX3-1", "name": "Lysozyme-like protein 1", "aln": "--MKSVG--VFALIISFSIVAESKIYTRCKLAKIFAKAGLDNYGGFALGNWLCMAYYESHYNTTAEN-VLEDGSTDYGIFQINSFTWCR-NARKHQKNHCHVACS------ALITDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSEWKRGCEVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWQ5-1", "uniprot_id": "LYZL1_HUMAN", "id": "Q6UWQ5-1", "name": "Lysozyme-like protein 1", "aln": "--MKAAG--ILTLIGCLVTGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQT-VLDDGSIDYGIFQINSFAWCR-RGKLKENNHCHVACS------ALITDDLTDAIICARKIVKETQGMNYWQGWKKHCEGRDLSEWKKGCEVS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37161-1", "uniprot_id": "LYSX_DROME", "id": "P37161-1", "name": "Lysozyme X", "aln": "--MRALL--GICVLALVTPAVLGRTMDRCSLAREMANMGVSRDQ---LSKWACIAEHESSYRTGVVGPPNTDGSNDYGIFQINDMYWCQPSSGKFSHNGCDVSCN------ALLTDDIKSSVRCALKVLG-QQGWSAWSTWH-YCSG--YLPPIDDCFV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00709-1", "uniprot_id": "LALBA_HUMAN", "id": "P00709-1", "name": "Alpha-lactalbumin", "aln": "--MRFFVP--LFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQAIVENNES--TEYGLFQISNKLWCKSSQVPQSRNICDISCD------KFLDDDITDDIMCAKKILD-IKGIDYWLAHKALCTEKLEQWLCEKL-------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* :: : : : . * * : . :**:**:.. ** * * : * . . * : ", "identical_positions": 13, "similar_positions": 20, "identity": "7.65%" }, { "cls_id": "homologset.agr.FB:FBgn0004432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4J2A2-1", "uniprot_id": "PAL4C_HUMAN", "id": "A0A0B4J2A2-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4C", "aln": "---------------------------------------------------------------MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B767-1", "uniprot_id": "PAL4H_HUMAN", "id": "A0A075B767-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "aln": "---------------------------------------------------------------MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DN37-1", "uniprot_id": "PAL4G_HUMAN", "id": "P0DN37-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4G", "aln": "---------------------------------------------------------------MVNSVIFFDITVDGKPLGRISIKQFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTHPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B759-1", "uniprot_id": "PAL4E_HUMAN", "id": "A0A075B759-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "aln": "---------------------------------------------------------------MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DN26-1", "uniprot_id": "PAL4F_HUMAN", "id": "P0DN26-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4F", "aln": "---------------------------------------------------------------MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F5H284-1", "uniprot_id": "PAL4D_HUMAN", "id": "F5H284-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "aln": "---------------------------------------------------------------MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y536-1", "uniprot_id": "PAL4A_HUMAN", "id": "Q9Y536-1", "name": "Peptidyl-prolyl cis-trans isomerase A-like 4A", "aln": "---------------------------------------------------------------MVNSVVFFDITVDGKPLGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRN-----------------SKTS---KKITIADCGQF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17742-1", "uniprot_id": "PPIA_MOUSE", "id": "P17742-1", "name": "Peptidyl-prolyl cis-trans isomerase A", "aln": "---------------------------------------------------------------MVNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRN-----------------GKTS---KKITISDCGQL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10111-1", "uniprot_id": "PPIA_RAT", "id": "P10111-1", "name": "Peptidyl-prolyl cis-trans isomerase A", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMSIVEAMERFGSRN-----------------GKTS---KKITISDCGQL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62937-1", "uniprot_id": "PPIA_HUMAN", "id": "P62937-1", "name": "Peptidyl-prolyl cis-trans isomerase A", "aln": "---------------------------------------------------------------MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRN-----------------GKTS---KKITIADCGQLE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LGT7-1", "uniprot_id": "A0ABK0LGT7_RAT", "id": "A0ABK0LGT7-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNPTVFFDITADGEPLGRVCFELFADEVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTCHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGK-------VKEDHHLRLWT--------------TLISLTCGHFTHQTIPSVAQESTPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCZ9-1", "uniprot_id": "M0RCZ9_RAT", "id": "M0RCZ9-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MVNLTMFFNITADGEPLGRVSLELFADKVPRTAENFRSLTTGEKGFGYKGSSFHRIIPGFMCQGGKVTCHNGTGGKSIYGEKFENDSFILKHTGPGILSMANAGPNTNGSQFFICTAKTERLDGKCVVFGKGRGGTNIVEAMEHFGSRNGKTSKKITISDCGQLLVSLICGHFTHQTIPSVAQESAPTPSARNTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29117-1", "uniprot_id": "PPIF_RAT", "id": "P29117-1", "name": "Peptidyl-prolyl cis-trans isomerase F, mitochondrial", "aln": "----------MLALRCGPRLLGLLSGPRSAPLLLSTTRTC-----------SDG-GARGANSSSQNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKS-----------------GKTS---KKIVITDCGQLS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KR7-1", "uniprot_id": "PPIF_MOUSE", "id": "Q99KR7-1", "name": "Peptidyl-prolyl cis-trans isomerase F, mitochondrial", "aln": "----------MLALRCGPRLLGLLSGPRSAPLLLSATRTC-----------SDG-GARGANSSSGNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGRSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKS-----------------GKTS---KKIVITDCGQLS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30405-1", "uniprot_id": "PPIF_HUMAN", "id": "P30405-1", "name": "Peptidyl-prolyl cis-trans isomerase F, mitochondrial", "aln": "----------MLALRCGSRWLGLLSVPRSVPLRLPAARAC-----------SKGSGDPSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKS-----------------GRTS---KKIVITDCGQLS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25007-1", "uniprot_id": "PPIA_DROME", "id": "P25007-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MVSFCATLIRQFRHRSAAAFQIAESAILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQS-----------------GKTS---KKIIVANSGSL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PHT1-1", "uniprot_id": "A0A8M1PHT1_DANRE", "id": "A0A8M1PHT1-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------------MARPKVFFDLTAGGSPVGRVVMELRTDVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFTNHNGTGGKSIYGNKFADENFNLKHTGAGCLSMANAGPNTNGSQFFICTALTSWLDGKHVVFGQVVEGLDVIKKVEGFGSSS-----------------GKTS---AKIIIADCGQL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25719-1", "uniprot_id": "CYPC_YEAST", "id": "P25719-1", "name": "Peptidyl-prolyl cis-trans isomerase C, mitochondrial", "aln": "---------------------------------------------MFKRSIIQQSRLFSNSASRLGKKVFFDPAVNGTKIGRIEFELYDNVVPKTAENFRALCTGEKGWGYKGVPFHRIIPDFMIQGGDTDLTNGFGGKSIYGSKFADENFVKKHDKAGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVTKGMDIVKAIESYGTAS-----------------GKPR---AEIVIEEAGEL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "id": "P14832-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "---------------------------------------------------------MS--------QVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPS-----------------GATK---ARIVVAKSGEL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: .. :**: :: : : :****** * **: *: * * ***:** ** *.*. ** ..:**** :* ::.: :* .* ***.***.******:** : **.* *.**. :: . . . . : . .. ", "identical_positions": 52, "similar_positions": 45, "identity": "20.16%" }, { "cls_id": "homologset.agr.FB:FBgn0004435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P82471-1", "uniprot_id": "GNAQ_RAT", "id": "P82471-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "-----------MTLESIMACCLSEEA------------KEARRIN--DEIERQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMVRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPY----VDAIKSLWNDPGIQECYD--RRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21279-1", "uniprot_id": "GNAQ_MOUSE", "id": "P21279-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "-----------MTLESIMACCLSEEA------------KEARRIN--DEIERQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPY----VDAIKSLWNDPGIQECYD--RRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50148-1", "uniprot_id": "GNAQ_HUMAN", "id": "P50148-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "-----------MTLESIMACCLSEEA------------KEARRIN--DEIERQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPY----VDAIKSLWNDPGIQECYD--RRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JID2-1", "uniprot_id": "GNA11_RAT", "id": "Q9JID2-1", "name": "Guanine nucleotide-binding protein subunit alpha-11", "aln": "-----------MTLESMIACCLSDEV------------KESKRIN--AEIEKQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAVVRAMDTLKIRYKYEQNKANALLIREVDVEKVTTFEHQY----VNAIKTLWSDPGVQECYD--RRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQHSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21278-1", "uniprot_id": "GNA11_MOUSE", "id": "P21278-1", "name": "Guanine nucleotide-binding protein subunit alpha-11", "aln": "-----------MTLESMMACCLSDEV------------KESKRIN--AEIEKQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQY----VNAIKTLWSDPGVQECYD--RRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29992-1", "uniprot_id": "GNA11_HUMAN", "id": "P29992-1", "name": "Guanine nucleotide-binding protein subunit alpha-11", "aln": "-----------MTLESMMACCLSDEV------------KESKRIN--AEIEKQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQY----VSAIKTLWEDPGIQECYD--RRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8XRQ3-1", "uniprot_id": "A0A8J8XRQ3_RAT", "id": "A0A8J8XRQ3-1", "name": "Guanine nucleotide-binding protein subunit alpha", "aln": "---------------MAGCCCLSAEE------------KESQRIS--AEIERQLRR----------DKKDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYTCEQNKENAQIIREVEVDKVSAISRDQ----VAAIKQLWLDPGIQECYD--RRREYQLSDSAKYYLTDIDRIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30677-1", "uniprot_id": "GNA14_MOUSE", "id": "P30677-1", "name": "Guanine nucleotide-binding protein subunit alpha-14", "aln": "---------------MAGCCCLSAEE------------KESQRIS--AEIERQLRR----------DKKDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTALSRDQ----VAAIKQLWLDPGIQECYD--RRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95837-1", "uniprot_id": "GNA14_HUMAN", "id": "O95837-1", "name": "Guanine nucleotide-binding protein subunit alpha-14", "aln": "---------------MAGCCCLSAEE------------KESQRIS--AEIERQLRR----------DKKDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQ----VEAIKQLWQDPGIQECYD--RRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFR-MVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23625-1", "uniprot_id": "GNAQ_DROME", "id": "P23625-1", "name": "G protein alpha q subunit", "aln": "-----------------MECCLSEEA------------KEQKRIN--QEIEKQLRR----------DKRDAR-------------------------------------------------RELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFEDPY----LNAIKTLWDDAGIQECYD--RRREYQLTDSAKYYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFR-MVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPKQDHAAAKQFVLKKYLACNPDPERQCYSHFTTATDTENIKLVFCAVKDTIMQNALKEFNLG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10823-1", "uniprot_id": "GPA2_YEAST", "id": "P10823-1", "name": "Guanine nucleotide-binding protein alpha-2 subunit", "aln": "MGLCASSEKNGSTPDTQTASAGSDNVGKAKVPPKQEPQKTVRTVNTANQQEKQQQRQQQPSPHNVKDRKEQNGSINNAISPTATANTSGSQQINIDSALRDRSSNVAAQPSLSDASSGSNDKELKVLLLGAGESGKSTVLQQLKILHQNGFSEQEIKEYIPLIYQNLLEIGRNLIQARTRFNVNLEPECELTQQDLSRTMSYEMPNNYTGQFPEDIAGVISTLWALPSTQDLVNGPNASKFYLMDSTPYFMENFTRITSPNYRPTQQDILRSRQMTSGIFDTVIDMGSDIKMHIYDVGGQRSERKKWIHCFDNVTLVIFCVSLSEYDQTLMEDKNQNRFQESLVLFDNIVNSRWFARTSVVLFLNKIDLFAEKLSKVPMENYFPDYTG-GSDINKAAKYILWRFVQLN-RANLSIYPHVTQATDTSNIRLVFAAIKETILENTLKDSGVLQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * : * : :. : *:* :* *::: . :***:****:*******.::*::*:* *:*::: : : *::**:: : :::* :.: . : :. : . .*. ** .. *: : . :: * **: *:: :. *: : **:**:** * *:**:: :*: . : : *********:******:.** ::* *:****** * * .*:**::** .** .*:. ** .:**:***** **: :*: : .***:: * * * .::* : * : *.*.* ****.**::**.*:*:**:: *:: .: ", "identical_positions": 120, "similar_positions": 114, "identity": "26.61%" }, { "cls_id": "homologset.agr.FB:FBgn0004436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63146-1", "uniprot_id": "UBE2B_HUMAN", "id": "P63146-1", "name": "Ubiquitin-conjugating enzyme E2 B", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDG----------TFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63149-1", "uniprot_id": "UBE2B_RAT", "id": "P63149-1", "name": "Ubiquitin-conjugating enzyme E2 B", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDG----------TFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63147-1", "uniprot_id": "UBE2B_MOUSE", "id": "P63147-1", "name": "Ubiquitin-conjugating enzyme E2 B", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDG----------TFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z255-1", "uniprot_id": "UBE2A_MOUSE", "id": "Q9Z255-1", "name": "Ubiquitin-conjugating enzyme E2 A", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDG----------TFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EWP1-1", "uniprot_id": "F7EWP1_RAT", "id": "F7EWP1-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "MWFQRQVVGSAPVYSGVVLSRRQTDPRLRRGSAVPLGAPSASASSASSGTADPGICPTSDPAKAMSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTHVETTGQLGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49459-1", "uniprot_id": "UBE2A_HUMAN", "id": "P49459-1", "name": "Ubiquitin-conjugating enzyme E2 A", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDG----------TFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25153-1", "uniprot_id": "UBCD6_DROME", "id": "P25153-1", "name": "Ubiquitin-conjugating enzyme E2-17 kDa", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRLQEDPPTGVSGAPTDNNIMIWNAVIFGPHDTPFEDG----------TFKLTIEFTEEYPNKPPTVRFVSKVFHPNVYADGGICLDILQNRWSPTYDVSAILTSIQSLLSDPNPNSPANSTAAQLYKENRREYEKRVKACVEQSFID---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06104-1", "uniprot_id": "UBC2_YEAST", "id": "P06104-1", "name": "Ubiquitin-conjugating enzyme E2 2", "aln": "----------------------------------------------------------------MSTPARRRLMRDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPADTPYEDG----------TFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVKETVEKSWEDDMDDMDDDDDDDDDDDDDEAD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***************::**.* ***.:* :*:* ***:*:** .**:*** **:* :** ******** *:*:*::*******:* **********:*****::********:.:*** **** ** *::::: :* ***. **:*: * ", "identical_positions": 100, "similar_positions": 33, "identity": "40.65%" }, { "cls_id": "homologset.agr.FB:FBgn0004449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1K2-1", "uniprot_id": "TEN2_RAT", "id": "Q9R1K2-1", "name": "Teneurin-2", "aln": "-------------------------MDVKDRRH-RSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHD-SRMHYGNRVTDLVHRESDEFSRQG--------------ANFTLAELGICEPSPHR-SGYCSDMGILHQ----GYSLSTGSDADSDTEGGMSPEHAIRLWGRG-IKSRRSSGLSSRENSALTLTDSDNENKSDD-----------------------------------------------DNGRPIPPTSSSSLLPSAQLPSSHNPPPVS-----CQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSG----PQQASSSGPPNHHSQSTLRPPLPPPHNHTLS--HHHSSANSLNRNSLTNRRSQ-IHAPAP-APNDLAT--TPESVQLQDSWVLNSNVPLETR---------------------------------HFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADG----HTFNNGVRTGLPGNDDVATVPSGGK-----------------VPWSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDG-----KEKWSVVES--PRERRSIQTLVQNEAVFVQYLDVGLWHLAFYND-GKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGLCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCAAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELA---RVQCPDQCSGHGTYLPDSGLCNCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIG-RQTAGTETDGCPDLCNGNGRCTLGQNS-WQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQ--TDWPAVKSFYDRIKLLAGKDSTHIIPGDNPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFDLIANGGSALTLHFERAPFMSRERTVWPPWNSFYAMDTLVMKTEENS------IPSCDLSGFVRPDPIIISSPLSTFFSASPAANPIVPETQVLHEEIELPGTNVKLRYLSSRTAGYKSLLKITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHTLNVKSGILLKGTGENQFLT-QQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLFVGDFNYIRRIFPSRNVTSILELRNKEFKHSNSPGHKYYLAVDPVTGSLYVSDTNSRRIYRVKSLSGAKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAVDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTLLG-SNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSIIAGRPMHCQVPGIDYSLS-KLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGEICLLAGAASDCDCKNDVNCICYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSA---DNDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKAVSTQNLELGLMTYDGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITVDIENSNRDNDVTVITNLSSVEASYTVVQDQVRNSYQLCSNGTLRVMYANGMGVSFHSEPHVL--------AGTLTPTIGRCNISLPMENG-----------LNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTLRIIYDQVGRPF-LWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADGKVWSYSYLDKSMVLLLQ----SQRQYIFEYDSSDRLHAVTMPSVARHSMSTHTSIGYIRNIYNPPES-NASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKVGPLVDKQIYRFS-EEGMINARFDYTYHDNSFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMT---LSKHFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLNGNLHLLNPGNSARLMPLRYDLRDRITRLGDVQYK-IDDDGYLCQRGSDIFEYNSKGLLTRAYNKASG-WSVQYRYDGVSRRASYKTNLGHHLQYFYSDLHHPTRITHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWRNVGKE-PAPFNLYMFKNNNPLSNELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELS----ESQASENGQLITGVQQTTERHNQAFLALEGQ-VISKKLHAGIREKAG-HWFATTTPIIGKGIMFAIK-EGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGAADGDLVTLGTT--IGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQNEMGKR----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTS5-1", "uniprot_id": "TEN2_MOUSE", "id": "Q9WTS5-1", "name": "Teneurin-2", "aln": "-------------------------MDVKDRRH-RSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHD-SRMHYGNRVTDLVHRESDEFSRQG--------------TNFTLAELGICEPSPHR-SGYCSDMGILHQ----GYSLSTGSDADSDTEGGMSPEHAIRLWGRG-IKSRRSSGLSSRENSALTLTDSDNENKSDD-----------------------------------------------DNGRPIPPTSSSSLLPSAQLPSSHNPPPVS-----CQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSG----PQQASSSGPPNHHSQSTLRPPLPPPHNHTLS--HHHSSANSLNRNSLTNRRSQ-IHAPAP-APNDLAT--TPESVQLQDSWVLNSNVPLETR---------------------------------HFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADG----HTFNNGVRTGLPGNDDVATVPSGGK-----------------VPWSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDG-----KEKWSVVES--PRERRSIQTLVQNEAVFVQYLDVGLWHLAFYND-GKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGLCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCAAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELA---RVQCPDQCSGHGTYLPDSGLCSCDPNWMGPDCSV-VCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTI----------DGCPDLCNGNGRCTLGQNS-WQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQ--TDWPAVKSFYDRIKLLAGKDSTHIIPGDNPFNSSLVSLIRGQVVTMDGTPLVGVNVSFVKYPKYGYTITRQDGTFDLIANGGSALTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENS------IPSCDLSGFVRPDPIIISSPLSTFFSASPASNPIVPETQVLHEEIELPGTNVKLRYLSSRTAGYKSLLKITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHTLNVKSGILHKGTGENQFLT-QQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLFVGDFNYIRRIFPSRNVTSILELRNKEFKHSNSPGHKYYLAVDPVTGSLYVSDTNSRRIYRVKSLSGAKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAVDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTLLG-SNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSIIAGRPMHCQVPGIDYSLS-KLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGEICLLAGAASDCDCKNDVNCICYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSA---DNDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKAVSTQNLELGLMTYDGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDDDVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMAVSFHSEPHVL--------AGTITPTIGRCNISLPMENG-----------LNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTLRIIYDQVGRPF-LWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADGKVWSYSYLDKSMVLLLQ----SQRQYIFEYDSSDRLHAVTMPSVARHSMSTHTSIGYIRNIYNPPES-NASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKVGPLVDKQIYRFS-EEGMINARFDYTYHDNSFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMT---LSKHFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLNGNLHLLNPGNSARLMPLRYDLRDRITRLGDVQYK-IDDDGYLCQRGSDIFEYNSKGLLTRAYNKASG-WSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVYSINGLMIKQLQYTAYGEIYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWRNVGKE-PAPFNLYMFKNNNPLSNELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELS----ESQASENGQLITGVQQTTERHNQAFLALEGQ-VITKKLHASIREKAG-HWFATTTPIIGKGIMFAIK-EGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGAADGDLVTLGTT--IGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQAGQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQNEMGKR----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NT68-1", "uniprot_id": "TEN2_HUMAN", "id": "Q9NT68-1", "name": "Teneurin-2", "aln": "-------------------------MDVKDRRH-RSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHD-SRMHYGNRVTDLIHRESDEFPRQG--------------TNFTLAELGICEPSPHR-SGYCSDMGILHQ----GYSLSTGSDADSDTEGGMSPEHAIRLWGRG-IKSRRSSGLSSRENSALTLTDSDNENKSDD-----------------------------------------------ENGRPIPPTSSPSLLPSAQLPSSHNPPPVS-----CQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSG----PQQASSSGPPNHHSQSTLRPPLPPPHNHTLS--HHHSSANSLNRNSLTNRRSQ-IHAPAP-APNDLAT--TPESVQLQDSWVLNSNVPLETR---------------------------------HFLFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAALSAIAAALLLAILLAYFIAMHLLGLNWQLQPADG----HTFNNGIRTGLPGNDDVATMPSGGK-----------------VPWSLKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDG-----KEKWSVVES--PRERRSIQTLVQNEAVFVQYLDVGLWHLAFYND-GKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELA---RVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIG-RQTAGTETDGCPDLCNGNGRCTLGQNS-WQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQ--TDWPAVKSFYDRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENS------IPSCDLSGFVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLLKITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQFLT-QQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIFPSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTLLG-SNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSIIAGRPMHCQVPGIDYSLS-KLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYST---DNDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTYDGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDDDVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVL--------AGTITPTIGRCNISLPMENG-----------LNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFTLRIIYDQVGRPF-LWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIVSRMFADGKVWSYSYLDKSMVLLLQ----SQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGYIRNIYNPPES-NASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFS-EEGMVNARFDYTYHDNSFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMT---LSKHFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTWRYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYK-IDDDGYLCQRGSDIFEYNSKGLLTRAYNKASG-WSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKE-PAPFNLYMFKSNNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYELS----ESQASENGQLITGVQQTTERHNQAFMALEGQ-VITKKLHASIREKAG-HWFATTTPIIGKGIMFAIK-EGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGTT--IGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQNEMGKR----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TFW5-1", "uniprot_id": "A0AB32TFW5_DANRE", "id": "A0AB32TFW5-1", "name": "Teneurin-2", "aln": "-------------------------MDLKDRR--RSLTRGTSGKEMHYATSSLDSENCHIVSQKSYSSSKTLKAYQQD-GRLRYGACVAELVHQETEEYVRQAYVELAPVAVGYYLSGSFALADLGMCEPPPPS-SVYCSDISLLQD----RYSLNAVSDADSDPEGVMTPERAVQLWSRQPLKSRRSSCLSSPDHSVLTLTDSENEHKTDEESAYFDDEDEDLFGDYYFRFLTDFRAGRKSRGEMHHPGIHRAKALHYDPGRPLPPTPSSSLLPPAPPPPSVPLHQAASSIRECQMPLLDSGSSHTILDPPPEDEFSPNSYLLRAQPP----ITGASS-----HHSQTSLRPPLPPPHNH-----HHQSSANSLNRSAQAGRRNQQSHAPAAVAPPDGPS--TPESVQLQDSWALNSSVPLETR---------------------------------HFLFKTPSGSTPLFSSSSPGYPLTGGTVYSPPPRLLPRNTFSRSSFKLKKPSKYCSWKCAAVSAIAAAVLLAVLLSYVIALNLLGLNWRLKPTEG----HLVNTGLSMSIPGIGDVATVPSGGR-----------------GPWVLKNSSISSGELELGQRVSQDVPPGVFWRSLLHLRQPHFLKFNISLGKDALFGVYMRKGLPPSHAQYDFMERLDG-----KEKWSVIES--PRERRSIQTVVQNEAIFVQYLDPGTWHLAFYND-GKEKEPVSFSTVALDSVEECSQNCHGNGECMSGACHCFPGFHGSDCSKVACPVLCSGNGQYSKGVCMCYSGWKGLECDVPQGQCVDPSCGGHGTCAQGSCTCEAGYRGESCEEVDCLDPTCSGHGSCVSGQCHCKPGWSGPLCDVS---RAQCPDQCNGHGVYSPDTGLCSCDPNWMGPDCSTEVCSADCGSHGVCVGGVCHCEEGWTGTSCDQRLCNPQCVKHGTCRDGKCQCEQGWNGEHCTI----------DGCPGLCNGNGQCIMGQNS-WHCECHTGWRGPGCSVAMETSCNDNKDNEGDGLVDCMDPDCCTQSSCMTNPLCRGSRDPLQVIQQSQ--SEVQKVPSFYDRIKMLVGKDSTHIIPGINPFNASLASLIRGQVLTSDGTPLVGVNVTFVKYPHYGHTMTRQDGTFDLVANGGGSLALRFERAPFQSQERTVWLPWNRFYAMDTLVLQTEEKP------TARCDLSGFVRPDPIVLPSPLSSFFSSNPSERHILPESQVLHEQVEIPGTSLKLCYLSSRTSGYLSLLKVIMTPALVPLSLAKVHLMVAVEGHLLQKWFHASPNLAYTYIWDKTDAYRQRVHGLTEALVSVGYEYETCPGQLLWEKRTAVLQGYELNPSNLGSWSLDKHHMLNVRSGILHKGSGENIFLSQQQPPIINSIMGNGRRRSISCPSCSGMAEGNKLLAPMAVACDGDGNLYVGDLNFVRRVYPSLNTTAVLELRNKDLRHSNSPSHKYYLAVDPMSGSLFLSDTNSRQIYRVRSLNGARPLLDNAQVVAGTGEQCVPFDEARCGDGGKALEATLMSPRGVALDKNGLMYFVDATMIRKVDQNGIISTLIK-TNDLTAVRPLSCDSSMDVSQVRLEWPTDLAINPMDNSLYVLENNVILRISENHQVSIIAGRPMHCQVPGIDYSLS-KLAIHSALESATAIAISHTGVLYIAETDEKRINRIRQVSTSGEISLVAGATSECDCKNDVNCNCFSGDEGYAADAFLNCPTSLAVSPDGTLYIADLNNIRVRSVRGNRPNATASGQYEVGSSLEQELYVFSADGLHRQTISLITGLPLYNFTYGL---DRELAAVTDASNNTLRVRREASGSIRLVLLPENQVVTLGMDPAGNLRSVSALSQEVAQLSYDANTELLASKSDETGWTNFYNYDNEGRLTNVTYPTGVVTSLRREMEESINIDMESSNRDDDVTVVTNLSSVEASYTVVQDQVRNSYQLYHNGTLRVSYANGMGISFHTEPHII--------AGSVSPTIGRRNISLPTDSG-----------LNSIEWRMRKELTKGKVTVFGRKLRVHSRNLLSIDYDRNTRTEKIYDDHRKFTLRIIYDAQGRPA-TWLPSSSLALVNVSYSPTGRLVGLQRGSMSEKSEFDTFGRILSRTFVDGKIWSFSYVDKSMVLLLQQ---SQKQYVFDFDTAGRLTAVTMPSMARHTMATHVSVGYIRNTYNPPES-NATVIHDFSEDGRPCAMFYLGTGRRVLYKYGKLGKLSEVLYDATAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKLGPLVDKQMYRFS-EEGMVNARFDYTYHDNSFRVASIKPVIGETPLPVDLYRYDEISGKVEHFGKFGIIYYDINQIITTAVMT---LSKHFDAHGRIKEVQYEIFRSLMYWMTVQYDSMGRVIKRELKIGPYANTTQYRYEYDGDGQLVGVKVDDWSTWRYSYDLNGNLHLLNPGNSARLLPLRYDLRDRITRLGDMQYQ-LDEDGVLMQRGSDVFEYNSKGLLERAYSRTAGGWSVRYRYDGLGRRVSRRTSEGEHQQYFYADLNYPTRVTHVYNHTRAEITSFYYDLQGHLFAMEVSGGEEYYIASDNVGTPLAIFSSNGQMVKQMQYTAYGEIYHDSNPDFQLILGFHGGLYDSLTKLVHFAQRDYDVLAGRWIAPDHTLWSKIGKE-PAPFNLYMFKNNNPLSDMIDVKNYVTDVKSWLVMFGFQLSNIIPGFPRHSLYFVNPPYEIF----ASQDSDNAQLFTGVQHSVDRHNQAFMVLEGR-RLNKQRRT-KHDKPG-YWFGTSTPIVGKGMMLAIK-EGHVLTDLSSSASEDSRKISQILSNAIYLEGTHYTIEGRDCHFFVKLGLADSDLLALGLS--GGHKSLESGINITIS-------GRSRRGVTLEIHSSKLTYSIRYGLSAEALEKERSRVLEQAHQRALSGAWAREQQQVREGREGGRVWAETERGQLLAMGKVAGYEGYYVLPVEQYPELADSSANIQFLKQNEMGRR----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5Y4Y3-1", "uniprot_id": "A0A8I5Y4Y3_RAT", "id": "A0A8I5Y4Y3-1", "name": "Teneurin-3", "aln": "-------------------------MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSSETLKAFDHDSSRLLYGNRVKDLVHREADEYPRQG--------------QNFTLRQLGVCESATRRGVAFCAEMGLPHR----GYSISAGSDADTENEAVMSPEHAMRLWGRG-VKSGRSSCLSSRSNSALTLTDTEHENRSDS---------------------------------------------------------------ESEQPAN--------------------------------------------------------------NQGQPTLQP-LPPSHKQHPA---HHPSVTSLNRNSLTNRRNQ-SPAPPAALPAELQT--TPESVQLQDSWVLGSNVPLESR---------------------------------HFLFKTGTGTTPLFSTATPGYTMASGSVYSPPTRPLPRNTLSRSAFKFKKSSRYCSWRCTALCAVGVSVLLAILLSYFIAMHLFGLNWHLQQTEN----DTFENGKVNSDTVPTHTVSLPSGDNGKL--------------GGFTHENNTIDSGELDIGRRAIQEVPPGIFWRSQLFIDQPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFVELLDGSRLIAREQRNLVDS--ERAGRQARSVSLHEAGFIQYLDSGIWHLAFYND-GKNPEQVSFNTIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGENCEEADCLDPGCSNHGVCIHGECHCNPGWGGGNCEIL---KTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTI----------EGCPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLVDCMDPDCCLQSSCQNQPYCRGLPDPQDVISQSLQTPSQQAAKSFYDRISFLIGSDSTHVLPGESPFNKSLASVIRGQVLTADGTPLIGVNVSFLHYSEYGYTITRQDGMFDLVANGGASLTLVFERSPFLTQHHTVWIPWNVFYVMDTLVMKKEEND------IPSCDLSGFVRPSPVIVSSPLSTFFRSSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKSVLKVTMTQATIPFNLMKVHLMVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSEAVVSVGYEYESCLDLTLWEKRTAILQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENQFIS-QQPPVVSSIMGNGRRRSISCPSCNGQADGNKLLAPVALACGIDGSLYVGDFNYVRRIFPSGNVTSVLELS-------SNPAHRYYLATDPVTGDLYVSDTNTRRIYRPKSLTGAKDLTKNAEVVAGTGEQCLPFDEARCGDGGKAVEATLMSPKGMAIDKNGLIYFVDGTMIRKVDQNGIISTLLG-SNDLTSARPLTCDTSMHISQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIAAGRPMHCQVPGVEYPVG-KHAVQTTLESATAIAVSYSGVLYITETDEKKINRIRQVTTDGEISLVAGIPSECDCKNDANCDCYQTGDGYAKDAKLSAPSSLAASPDGTLYIADLGNIRIRAVSKNKPLLNSMNFYEVASPTDQELYIFDINGTHQYTVSLVTGDYLYNFSYSN---DNDVTAVTDSNGNTLRIRRDPNRMPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLELVLFTYHGNSGLLATKSDETGWTTFFDYDSEGRLTNVTFPTGVVTNLHGDMDKAITVDIESSSREEDVSITSNLSSIDSFYTMVQDQLRNSYQIGYDGSLRIFYASGLDSHYQTEPHVL--------AGTANPTVAKRNMTLPGENG-----------QNLVEWRFRKEQAQGKVNVFGRKLRVNGRNLLSVDFDRTTKTEKIYDDHRKFLLRIAYDTSGHPT-LWLPSSKLMAVNVTYSSTGQIASIQRGTTSEKVDYDSQGRIVSRVFADGKTWSYTYLEKSMVLLLH----SQRQYIFEYDMWDRLSAITMPSVARHTMQTIRSIGYYRNIYNPPES-NASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSFTYDETAGVLKTVNLQSDGFICTIRYRQIGPLIDRQIFRFS-EDGMVNARFDYSY-DNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMT---YTKHFDAHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIMWRYNYDLNGNLHLLNPSSSARLTPLRYDLRDRITRLGDVQYR-LDEDGFLRQRGTEIFEYSSKGLLTRVYSKGSG-WTVIYRYDGLGRRVSSKTSLGQHLQFFYADLTYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGDEFYIASDNTGTPLAVFSSNGLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDIEIWKRIGKD-PAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELV----KSQQWEDVPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRKAGGEQSW-LWFATVKSLIGKGVMLAVS-QGRVQTNVLNIANEDCIKVAAVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLGTLRLT--SGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALALHVRYGMT---LDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQYPELADSANNIQFLRQSEIGKR----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTS6-1", "uniprot_id": "TEN3_MOUSE", "id": "Q9WTS6-1", "name": "Teneurin-3", "aln": "-------------------------MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSSETLKAFDHDYSRLLYGNRVKDLVHREADEYTRQG--------------QNFTLRQLGVCESATRRGVAFCAEMGLPHR----GYSISAGSDADTENEAVMSPEHAMRLWGRG-VKSGRSSCLSSRSNSALTLTDTEHENRSDS---------------------------------------------------------------ESEQPSN--------------------------------------------------------------NPGQPTLQP-LPPSHKQHPA--QHHPSITSLNRNSLTNRRNQ-SPAPPAALPAELQT--TPESVQLQDSWVLGSNVPLESR---------------------------------HFLFKTGTGTTPLFSTATPGYTMASGSVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWRCTALCAVGVSVLLAILLSYFIAMHLFGLNWHLQQTEN----DTFENGKVNSDTVPTNTVSLPSGDNGKL--------------GGFTHENNTIDSGELDIGRRAIQEVPPGIFWRSQLFIDQPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFVELLDGSRLIAREQRNLVES--ERAGRQARSVSLHEAGFIQYLDSGIWHLAFYND-GKNPEQVSFNTIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGENCEEADCLDPGCSNHGVCIHGECHCNPGWGGSNCEIL---KTMCADQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGSCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIA-HYLDKIVKEGCPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDCCLQSSCQNQPYCRGLPDPQDIISQSLQTPSQQAAKSFYDRISFLIGSDSTHVLPGESPFNKSLASVIRGQVLTADGTPLIGVNVSFLHYSEYGYTITRQDGMFDLVANGGASLTLVFERSPFLTQYHTVWIPWNVFYVMDTLVMKKEEND------IPSCDLSGFVRPSPIIVSSPLSTFFRSSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKSVLKITMTQAVIPFNLMKVHLMVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSEAVVSVGYEYESCLDLTLWEKRTAVLQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENQFIS-QQPPVVSSIMGNGRRRSISCPSCNGQADGNKLLAPVALACGIDGSLYVGDFNYVRRIFPSGNVTSVLELRNKDFRHSSNPAHRYYLATDPVTGDLYVSDTNTRRIYRPKSLTGAKDLTKNAEVVAGTGEQCLPFDEARCGDGGKAVEATLMSPKGMAIDKNGLIYFVDGTMIRKVDQNGIISTLLG-SNDLTSARPLTCDTSMHISQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIAAGRPMHCQVPGVEYPVG-KHAVQTTLESATAIAVSYSGVLYITETDEKKINRIRQVTTDGEISLVAGIPSECDCKNDANCDCYQSGDGYAKDAKLNAPSSLAASPDGTLYIADLGNIRIRAVSKNKPLLNSMNFYEVASPTDQELYIFDINGTHQYTVSLVTGDYLYNFSYSN---DNDVTAVTDSNGNTLRIRRDPNRMPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLELVLFTYHGNSGLLATKSDETGWTTFFDYDSEGRLTNVTFPTGVVTNLHGDMDKAITVDIESSSREEDVSITSNLSSIDSFYTMVQDQLRNSYQIGYDGSLRIFYASGLDSHYQTEPHVL--------AGTANPTVAKRNMTLPGENG-----------QNLVEWRFRKEQAQGKVNVFGRKLRVNGRNLLSVDFDRTTKTEKIYDDHRKFLLRIAYDTSGHPT-LWLPSSKLMAVNVTYSSTGQIASIQRGTTSEKVDYDSQGRIVSRVFADGKTWSYTYLEKSMVLLLH----SQRQYIFEYDMWDRLSAITMPSVARHTMQTIRSIGYYRNIYNPPES-NASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSFTYDETAGVLKTVNLQSDGFICTIRYRQIGPLIDRQIFRFS-EDGMVNARFDYSY-DNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMT---YTKHFDAHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIMWRYNYDLNGNLHLLNPSSSARLTPLRYDLRDRITRLGDVQYR-LDEDGFLRQRGTEIFEYSSKGLLTRVYSKGSG-WTVIYRYDGLGRRVSSKTSLGQHLQFFYADLTYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGDEFYIASDNTGTPLAVFSSNGLMLKQTQYTAYGEIYFDSNVDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDIEIWKRIGKD-PAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELV----KSQQWEDVPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRKAGAEQSW-LWFATVKSLIGKGVMLAVS-QGRVQTNVLNIANEDCIKVAAVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLGTLRLT--SGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALALHVRYGMT---LDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQYPELADSANNIQFLRQSEIGKR----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P273-1", "uniprot_id": "TEN3_HUMAN", "id": "Q9P273-1", "name": "Teneurin-3", "aln": "-------------------------MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSSETLKAFDHDSSRLLYGNRVKDLVHREADEFTRQG--------------QNFTLRQLGVCEPATRRGLAFCAEMGLPHR----GYSISAGSDADTENEAVMSPEHAMRLWGRG-VKSGRSSCLSSRSNSALTLTDTEHENKSDS---------------------------------------------------------------ENEQPAS--------------------------------------------------------------NQGQSTLQP-LPPSHKQHSA--QHHPSITSLNRNSLTNRRNQ-SPAPPAALPAELQT--TPESVQLQDSWVLGSNVPLESR---------------------------------HFLFKTGTGTTPLFSTATPGYTMASGSVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWKCTALCAVGVSVLLAILLSYFIAMHLFGLNWQLQQTEN----DTFENGKVNSDTMPTNTVSLPSGDNGKL--------------GGFTQENNTIDSGELDIGRRAIQEIPPGIFWRSQLFIDQPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFVELLDGSRLIAREQRSLLET--ERAGRQARSVSLHEAGFIQYLDSGIWHLAFYND-GKNAEQVSFNTIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWGGSNCEIL---KTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTI----------EGCPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDCCLQSSCQNQPYCRGLPDPQDIISQSLQSPSQQAAKSFYDRISFLIGSDSTHVIPGESPFNKSLASVIRGQVLTADGTPLIGVNVSFFHYPEYGYTITRQDGMFDLVANGGASLTLVFERSPFLTQYHTVWIPWNVFYVMDTLVMKKEEND------IPSCDLSGFVRPNPIIVSSPLSTFFRSSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKSVLKITMTQSIIPFNLMKVHLMVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSEAVVSVGYEYESCLDLTLWEKRTAILQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENQFIS-QQPPVVSSIMGNGRRRSISCPSCNGQADGNKLLAPVALACGIDGSLYVGDFNYVRRIFPSGNVTSVLELS-------SNPAHRYYLATDPVTGDLYVSDTNTRRIYRPKSLTGAKDLTKNAEVVAGTGEQCLPFDEARCGDGGKAVEATLMSPKGMAVDKNGLIYFVDGTMIRKVDQNGIISTLLG-SNDLTSARPLTCDTSMHISQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIAAGRPMHCQVPGVEYPVG-KHAVQTTLESATAIAVSYSGVLYITETDEKKINRIRQVTTDGEISLVAGIPSECDCKNDANCDCYQSGDGYAKDAKLSAPSSLAASPDGTLYIADLGNIRIRAVSKNKPLLNSMNFYEVASPTDQELYIFDINGTHQYTVSLVTGDYLYNFSYSN---DNDITAVTDSNGNTLRIRRDPNRMPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLELVLFTYHGNSGLLATKSDETGWTTFFDYDSEGRLTNVTFPTGVVTNLHGDMDKAITVDIESSSREEDVSITSNLSSIDSFYTMVQDQLRNSYQIGYDGSLRIIYASGLDSHYQTEPHVL--------AGTANPTVAKRNMTLPGENG-----------QNLVEWRFRKEQAQGKVNVFGRKLRVNGRNLLSVDFDRTTKTEKIYDDHRKFLLRIAYDTSGHPT-LWLPSSKLMAVNVTYSSTGQIASIQRGTTSEKVDYDGQGRIVSRVFADGKTWSYTYLEKSMVLLLH----SQRQYIFEYDMWDRLSAITMPSVARHTMQTIRSIGYYRNIYNPPES-NASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSFTYDETAGVLKTVNLQSDGFICTIRYRQIGPLIDRQIFRFS-EDGMVNARFDYSY-DNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMT---YTKHFDAHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIMWRYNYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGDVQYR-LDEDGFLRQRGTEIFEYSSKGLLTRVYSKGSG-WTVIYRYDGLGRRVSSKTSLGQHLQFFYADLTYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGDEFYIASDNTGTPLAVFSSNGLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDIEIWKRIGKD-PAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELV----KSQQWDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGAQSW-LWFATVKSLIGKGVMLAVS-QGRVQTNVLNIANEDCIKVAAVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLGTLRLT--SGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALALHVRYGMT---LDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQYPELADSANNIQFLRQSEIGRR----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W7R4-1", "uniprot_id": "TEN3_DANRE", "id": "Q9W7R4-1", "name": "Teneurin-3", "aln": "-------------------------MDVKERRPYCSLTKSRREKERRYTGSSGDSEDCRVPTQKSYSSSETLKAFDHDSSRLLYGGHVKEMVHREADEYSRQG--------------QNFNLRQLGICEPATRRGLAFCAEMGMPSS----LSSPSVTEHSHSQPPSPNLHDNQSSILSNA-TTQAVQDSDSEEEYTAVLYRPVTQPAPSHS---------------------------------------------------------------CNEQPSNQH------------------------------------------------------------QQGQSTLPP-VPPPHKQQPS-------VTALNHNSLSSRRNV-SPAPPAALPAELQT--TPESVPLQDSWVLGSNVPLESR---------------------------------HFLFKTGTGTTPLFSTATPGYTMATGAVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWRCTALSAMAVSILLSVLLCYCIAMHLFGLNWQLQETEG----YAFENGQVKSDSTATNAVTALSTEN-----------------KVYFQENNTIDTGEVDVGRRAVQDVPPGTFWRTQLFIDQPQSLKFNISVQRGALVGVYGRKGLPPTHTQYDFVELLDGSRLIAKEKRGLVEV--EGAARKARSVNVHEAEFIRFLDSGTWHLAFYND-GKNAEQVSYNTIIIDTLTECPHNCHGNGDCRTGTCHCFPGFLGPDCSRAACPVLCSGNGQYSRGRCLCYSGWKGTECDVPSNQCIDIHCSGHGICIMGTCACNTGYKGDNCEEVDCLDPSCSSHGVCIHGECHCNPGWGGNNCEIL---KTMCPDQCSGHGTYQTESGTCTCDTNWTGPDCSIEVCAVDCGSHGVCIGGSCRCEEGWTGSVCDLKACHPRCTEHGTCKDGKCECHQGWTGEHCTV----------EGCPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCDVAMETLCADGKDNEGDGLVDCMDPDCCLQSSCQTQPFCRGSPDPIDIISQNQPASPQQAAQSFYQQISFLTGPESTHVINGENPFNRSLVSIIRGQVLTADGTPLIGVNVSFVHYPDHGYTITRQDGMFDILANGGASLTLSFERAPFLTQFRTVWIPWNVFYVMDTLVMKKEEND------IPSCDLSGFIRPSPLIVATPLSTFFRSSPENGPIIPETQVLQEETAIPGSDLNLMYLSSRAAGYRPVLKVTMTQATIPFNLMKVHLMVAVVGRLFQKWFPAEPNLSYTFIWDKTDAYNQRVYGLSEAVVSVGFEYESCLDLILWEKRTAILQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENVFVS-QQPPVISTIMGNGRRRSISCPSCNGQADGNKLLAPVALACGSDGSLFVGDFNYIRRIFPSGNVTSVMELS-------NNPAHRYYLATDPMTGQLYVSDTNSRRIFRPKALTGTKELLQNAEVVAGTGEQCLPFDEARCGDGGKATEALLLGPKGIAVDKNGFIYFVDGTMIRKVDRNGIISTLLG-SNDLTSARPLTCDNSMHIGQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIVAGRPMHCQVPGIEYTMG-KRAIQTTLEGATAISLSYSGVLYIAETDEKKINRIRQVSTDGEISHLAGAPSDCDCKNDANCDCYQTGDGYAKDARLNAPSSLVVSPDGTLYVADLGNIRIRAIRHNRPPQGSSGLFEVASPASQELYVFDSNGTHQYTMSLVTGDYKYNFSYSN---EDDVTAVTDSSGNTLRVRRDPNRMPVRIVAPDNQVIWLTIGTNGGLKTLTAQGQELVLFTYHGNSGLLATKSIQIGWTTFYDYDSEGRLTNVTFPTGVITSLIGEMDRALTVDIETSGRDDDVSITTNLSSIDSFYTLVQDQLRNSYQVGYDNSMRVIYANGMDSHFQTEPHIL--------AGASNPTVARRNMTLPGENG-----------QNLVEWRFRKEQNRGKVVVFGRKLRVNGRNLLSVDYDRSLRTEKIYDDHRKFLLKIVYDASGHPT-LWVPSSKLMSVNLTYSSTGQVTSLQRGPTTERVEYDSQGRIVSRTFADAKIWSYTYLDKSMVLLLH----SQRQYIFDYDLQDRLSAITMPSVARHTMQTIRSVGYYRNIYNPPES-NASVTVDYSEDGQLLRVAHLGTGRRVLYKYRRQNKLSEILYDSTRVSFTYDETAGVLKTVNLQSEGFICSIRYRQIGPLVDRQIFRFS-EDGMVNARFDYTY-DNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMT---YTKHFDVHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYGYEYDVDGQLQTVYLNEKMMWRYNYDLNGNLHLLNPGNSARLTPLRYDLRDRITRLGDVQYR-MDEDGFLRQRGAEIFEYNSKGLLVRVHSKASG-WTIQYRYDGLGRRLASRNSLGQHLQFFYADLNYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGEEFYIACDNTGTPLAVFSSNGLLLKQVQYTAYGEIYFDSNPDFQLVIGFHGGLYDPLTRLLHFGERDYDIQAGRWTTPDISTWTRVGKD-PAPFNLYMFRNNNPISKIHEVKEYVTDVNIWLVTFGFHLHNVIPGFPIPKFDLTQPSLEMR----KSQLWDDLPSISGVQQEVMRQAKAFLSFERMPEIQLSRRRSSREKPW-LWFATVKSLIGKGVMLAITSKGQVATNALNIANEDCIKVATVLNNAFYLEDLHFTVEGRDTHYFIKTSLPESDLGALRLT--SGRKSLENGVNVTVSQSTTVVNGRTRRFADVELQYGALALHVRYGMT---LDEEKARVLEQARQRALSSAWAREQQRVRDGEEGVRLWTEGEKRQLLSSGKVLGYDGYYVLSVEQYPELADSANNVQFLRQSEIGKR----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LJN5-1", "uniprot_id": "A0ABK0LJN5_RAT", "id": "A0ABK0LJN5-1", "name": "Teneurin-4", "aln": "MEPDHSALSAARAQFVDVEEREPEAMDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKGP-QKSYSSSETLKAYDQD-ARLAYGSRVKDMVPQESEEFCRTG--------------TNFTLRELGLGEMTPPHGTLYRTDIGLPHC----GYSMGASSDADLEADTVLSPEHPVRLWGRS-TRSGRSSCLSSRANSNLTLTDTEHENTETG------------------------------------------------APLHCSSASSTPIEQSPSPPPSPPANESQ-------RRLLGNGVAQPTPDSDSEEEFVPNSFLVKSGS--ASLGVAANDHPSGLQNHPRLRTPPPPLPHAHTPNQ-HHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGSAQEPTHAQDNWLLNSNIPLETRNLGKQPFLGTLQDNLIEMDILSASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFSRPAFNLKKPSKYCNWKCAALSAILISATLVILLAYFVAMHLFGLNWHLQPMEG--QMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKGKGAAEGKPSSLFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEARSLEGP--QRQSRGTVPPSSHETGFIQYLDSGIWHLAFYND-GKESEVVSFLTTTIESVENCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSSHGTCIMGTCICNPGYKGESCEEVDCMDPTCSSRGVCVRGECHCSVGWGGTNCETP---RATCLDQCSGHGTFLPDTGLCNCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIA-HYLDRVVKEGCPGLCNGNGRCTLDLNG-WHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHVNPLCLGSPDPLDIIQETQAPVSQQNLHSFYDRIKFLVGRDSTHVIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFINNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHEENE------IPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQALQEEIIIAGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTAVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGENQFVS-QQPPVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILEMRNKDFRHSHSPAHKYYLATDPMSGAVFLSDTNSRRVFKIKSTTVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRVDQNGIISTLLG-SNDLTSARPLSCDSVMDISQVRLEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPVLNTQNMYELSSPIDQELYLFDTSGKHLYTQSLPTGDYLYNFTYTG---DGDITHITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALRSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSKD-DVTITTNLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQSEPHLL--------AGTVNPTVGKRNVTLPIDNG-----------LNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPS-LWSPSSRLNGVNVTYSPGGHIAGIQRGIMSERMEYDQAGRITSRIFADGKMWSYTYLEKSMVLHLH----SQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEG-NASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDESAGMLKTVNLQNEGFTCTIRYRQIGPLIDRQIFRFT-EEGMVNARFDYNY-DNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMT---HTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDLRDRITRLGDVQYK-MDEDGFLRQRGGDVFEYNSAGLLIKAYNRASG-WSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKRLSSSSIVPFHLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDTDAMEPSYELVSTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLFGSTITSCQQAPETKKFASSGSIFGKGVKFALK-DGRVTTDIISVANEDGRRIAAILNNAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLS--GGRRTLENGVNVTVSQINTMLGGRTRRYTDIQLQYRALCLNTRYGTT---VDEEKVRVLELARQRAVRQAWAREQQRLREGEEGLRAWTDGEKQQVLNTGRVQGYDGFFVTSVEQYPELSDSANNIHFMRQSEMGRR----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHK6-1", "uniprot_id": "TEN4_MOUSE", "id": "Q3UHK6-1", "name": "Teneurin-4", "aln": "-------------------------MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKGP-QKSYSSSETLKAYDQD-ARLAYGSRVKDMVPQEAEEFCRTG--------------TNFTLRELGLGEMTPPHGTLYRTDIGLPHC----GYSMGASSDADLEADTVLSPEHPVRLWGRS-TRSGRSSCLSSRANSNLTLTDTEHENTET-------------------------------------------------------------------------------------------------------------------------------DHPSSLQNHPRLRTPPPPLPHAHTPNQ-HHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGSAQEPTHAQDNWLLNSNIPLETRNLGKQPFLGTLQDNLIEMDILSASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFSRPAFNLKKPSKYCNWKCAALSAILISATLVILLAYFVAMHLFGLNWHLQPMEGQMQMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKGKGAAEGKPSSLFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEARSLEGP--QRQSRGPVPPSSHETGFIQYLDSGIWHLAFYND-GKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSSHGTCIMGTCICNPGYKGESCEEVDCMDPTCSSRGVCVRGECHCSVGWGGTNCETP---RATCLDQCSGHGTFLPDTGLCNCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIA-HYLDRVVKEGCPGLCNGNGRCTLDLNG-WHCVCQLGWRGTGCDTSMETGCGDGKDNDGDGLVDCMDPDCCLQPLCHVNPLCLGSPDPLDIIQETQAPVSQQNLNSFYDRIKFLVGRDSTHSIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFINNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIVMRHEENE------IPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQALQEEIVIAGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTAVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGENQFVS-QQPPVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILEMRNKDFRHSHSPAHKYYLATDPMSGAVFLSDTNSRRVFKVKSTTVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRVDQNGIISTLLG-SNDLTSARPLSCDSVMEISQVRLEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYLFDTSGKHLYTQSLPTGDYLYNFTYTG---DGDITHITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALRSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSKD-DVTITTNLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHLL--------AGTVNPTVGKRNVTLPIDNG-----------LNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPS-LWSPSSRLNGVNVTYSPGGHIAGIQRGIMSERMEYDQAGRITSRIFADGKMWSYTYLEKSMVLHLH----SQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEG-NASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTVNLQNEGFTCTIRYRQIGPLIDRQIFRFT-EEGMVNARFDYNY-DNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMT---HTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDLRDRITRLGDVQYK-MDEDGFLRQRGGDVFEYNSAGLLIKAYNRASG-WSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKRLSSNSIVPFHLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDTDAMEPSYELVHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPETKKFASSGSIFGKGVKFALK-DGRVTTDIISVANEDGRRIAAILNNAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLS--GGRRTLENGVNVTVSQINTVLSGRTRRYTDIQLQYRALCLNTRYGTT---VDEEKVRVLELARQRAVRQAWAREQQRLREGEEGLRAWTDGEKQQVLNTGRVQGYDGFFVTSVEQYPELSDSANNIHFMRQSEMGRR----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6N022-1", "uniprot_id": "TEN4_HUMAN", "id": "Q6N022-1", "name": "Teneurin-4", "aln": "-------------------------MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKAP-QKSYSSSETLKAYDQD-ARLAYGSRVKDIVPQEAEEFCRTG--------------ANFTLRELGLEEVTPPHGTLYRTDIGLPHC----GYSMGAGSDADMEADTVLSPEHPVRLWGRS-TRSGRSSCLSSRANSNLTLTDTEHENTET-------------------------------------------------------------------------------------------------------------------------------DHPGGLQNHARLRTPPPPLSHAHTPNQ-HHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMDILGASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAFNLKKPSKYCNWKCAALSAIVISATLVILLAYFVAMHLFGLNWHLQPMEG--QMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEARSLEGT--PRQSRGTVPPSSHETGFIQYLDSGIWHLAFYND-GKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETP---RATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIA-HYLDRVVKEGCPGLCNGNGRCTLDLNG-WHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHEENE------IPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQALQEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGENQFVS-QQPPVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPMSGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLG-SNDLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTGDYLYNFTYTG---DGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSKD-DVTITTNLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHLL--------AGTVNPTVGKRNVTLPIDNG-----------LNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPS-LWSPSSRLNGVNVTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLH----SQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEG-NASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQIFRFT-EEGMVNARFDYNY-DNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMT---HTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYK-MDEDGFLRQRGGDIFEYNSAGLLIKAYNRAGS-WSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPKTKKFASSGSVFGKGVKFALK-DGRVTTDIISVANEDGRRVAAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLS--GGRRTLENGVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTT---LDEEKARVLELARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W7R3-1", "uniprot_id": "TEN4_DANRE", "id": "Q9W7R3-1", "name": "Teneurin-4", "aln": "-------------------------MEVKERRPYRSLTS-RRDTERRYTSSSADSEDGKIN-PKSYSSSETLKAFDQD-SRLAYGSRVKDLVHHEADEFSRQG--------------PDFSLRDMAFGDPVPPHMGAYRTEMGLPHR----DYSVSVASDADTETDGIMSPEHAVRLWGRSNTKSGRSSCLFSRANSNLTLTDTEHENTENG------------------------------------------------PPLHCSSASSSP-VDSPYPPPSHAANQSQ-------GRLLGNSGAQAGRDSESEDEFGPNSFLVKTGSGNVCTPAAATANEGSFQNHSRLRTPPLPLFHSHSPSQ-HHTASIGSLSRSNYTQRSNPSPAPTDSSAPNEGPT-SAQDSSSAQDNWLLNSNVPLETRNIAKQTFLETLQDNFIEMDILATARRDGAYTDGHFLFKPG-GTSPLYCTTSPGYPLTSSTVYSPPPRPLPRNTFSRPAFSLKKPYKHCNWKCAALSAILISVTLVFLLAYFIAMHLFGLNWHLQPVQR--QIYQLTEDNTSGLHLPTDLGLPPLGNTGLEFPDRGSR--DDGKLDGFFPEDSFIDMGEIDVGRKVAQLIPPGIFWRSQVFIDHPMYLKFNVSLSKDALVGIYGRRGLPPSHTQFDFVELLDGRRLLSQGLPGLDGPPFPAQQRSLVPITSHDTGCIQYMDSGIWHLAVYND-GKETEQVSFLTTAIDSIDDCPSNCFGNGDCVSGNCHCFPGFRGPDCSRASCPVLCSGNGQYLKGRCMCHSGWKGSECDVPTNQCIDITCSGHGTCIVGTCICNPSYKGENCEEVDCLDPTCSGRGVCVRGECHCFVGWGGPGCESP---RASCMEQCSGHGSFLADTNTCNCDHNWTGHDCSTELCAADCGGHGICVAGSCRCDEGWMGTGCEQRACHPRCSEHGTCKDGKCECSPGWNGEHCTI----------EGCPGLCNGNGRCTLGNNG-WYCVCQLGWRGAGCDTSMETACSDGKDNDGDGLTDCMDPDCCLQASCHTTSLCVGSPDPLDIIQETQISSSLSTLQSFYQRIHFLVGRDSTHVIPDVNPFDGIHACVIRGQVVTSDGTPLVGVNISFINKPAYGYTITRQDGSFDLVSNGGVAIGLRFERAPFITQEHTLWLPWGRFFVMDTIVMRHEVND------IPSCDLSSFTRPMPIVLPAPLTAFAGTCPERGIVVPEIQTLQEEVRIPGTDMRLGYLSSRTSGYKSLLRITLTHSTIPFSLMKVHLMVAVEGRLFRKWFSAAPNLSYDFVWDKTDVYSQKVYGLSEAFVSVGFEYESCPDLILWEKRTAVLQGYETTASNLGGWSVDKHHALNIQSGILHKGNGENIFIS-QQPPVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALACGSDGSLYVGDFNYVRRIFTTGNVTSVLELSN-------SPAHKYYLATSPVSGWLYLSDTSSRKVFKVKSLYAVKDVAKNLELVAGTGDQCLPYDETRCGDGGKAVEATLTNPRGITVDKYGVIFFVDGTMIRRIDQNGIISTLLG-FNDLTSARPLSCDSVMDISQVRLEWPTDLAVSPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGLDHFLVSKIAIHATLESANALAVSHNGLLYIAESDEKKINRVRQVSTNGEISLLAGAPSGCDCKNDANCDCYSGDDGYAKDAKLNAPSSLAVSPDGELFIADLGNIRIRYVRRNKAFLNPLNMYEISSPIDDELYLFDVNASHVFTQSLTTGDYLYNFTYSG---EGDLSSITDKNKNRVSIRRDSTGLPLWLMGPDGQTFWFTMGTNNALKSVAAQGQEIAVMTYHGSSGLLATKSNEDGWSTFYEYDNYGRLTNVTYPTGRVSSYRTDSDSTVRVQTEGSNKE-DITVTTNLSASGTFYTLMQDQVKNSYYIGLDGSLRLVLANGMEVSLHTEPHLL--------SGTVNPTISKRNVTLPIDNG-----------LNLVEWRQRKEQARGQVTVYGRRLRVHNRNLLSMDFDRVTRTEKVYDDHRKFTLRIHYDHAGRPT-LWAPSSRLNGVNVTYSPGGHIAGIQRGTMSVRMEYDQNGRITSKIFADGKSWSYTYLEKSMVLLLY----SQRQYIFEFDKNDRLSSVTMPNVARQTLETTRSIGYYRNTYRPPEG-NATVLQDYSEDGLLLQTIHQGTGRRVIYKYGKLSRLLEILYDTTRIAFSYDESAGMLKTVGLQSEGFACTIRYRQIGPLIDRQIFRFS-EEGMVNARFDYNY-DNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMT---HTKHFDAYGRVKEVQYEIFRSLMYWMMVQFDNMGRVVAKELKVGPYANTTRYAYEYDADGQLQVVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYR-LDEDGFLRQRGNDFFEYNSAGLLVKTYNKVNG-WTIKYRYDGLGRRVSSRSTQGHHLQFFYADLSSPTRVTHMYNHSSSEITSLYYDLQGHLFAMELSSGDEFYVACDNIGTPLAVFSGAGLMIKQILHTAFGEVYLDSNPSFQLVIGYQGGLYEPLTKLVHMGRRDYDVLAGRWTTPDHDIRKRLNSDNIVPFNLYMFKNNNPLSNSQETKCYMTDVNSWLVTFGFQLYNVIPGYRKPVTDAMEPSYELVHTQIKTQEWDSTKSVLGVQCEVQRQLKSFVRLERFGQIYSASDSGCPPTPLHTLFATGTSLFGKGVKVAIR-EGRVEADIISLANEDGRRIAAVLDKASYLQDLHFTIAGLDTHYFVKSGLVEGDLSLLGMT--VGQRTLETGVNVTVSQVNMVLGGRSRRITDIQMQYGTLSLNVRYGSS---VDEEKVRVLELARQRAVATAWAHERHRLRQGEEGSRAWTDGERQQLLSSGRVQGYEGFYIVSVDQFPELTDNINNVHFWRQTEMGRR----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5Y571-1", "uniprot_id": "A0A8I5Y571_RAT", "id": "A0A8I5Y571-1", "name": "Teneurin-1", "aln": "-------------------------MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKP-RQSFNSRETLHEYNQE-LRRNYNSQSRKRKDVEKS------------------------TQEIEFCETPPTLCSGYQTDMHSVSR---HGYQLEMGSDVDTETEGAASPDHALRMWIRG-MKSEHSSCLSSRANSALSLTDTDHERKSDGENGF--------------------------------------------KFSPVCCDMEAPADSAQDMQSSPHN-----------------------------------------------------------QFTFRPLPPPPPPPHACTCAR-KPPPTVDSLQRRSMTTRSQPSPAAPAPPTSTQDSV-------HLHNSWVLNSNIPLETR---------------------------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVG-----QIYANGISNGNPGTESMDTTYSPIG--GKVSDKSE-------KKVFPKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKSSDDI--QHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSSHGICVKGECHCSTGWGGVNCETP---LPICQEQCSGHGTFLLDTGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCAEHGQCRDGKCECSPGWEGDHCTIA-HYLDAVR-DGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNIVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQPLFSQHTSRLFYDRIKFLIGKDSTHVVPQEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFERSPFLSEKRTLWLPWNQFIVVEKVIMQRIVAD------PPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPEFILWEQRTVVLQGFEMDASNLGGWSLNKHHIFNPQSGIIHKGNGENMFIS-QQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGKASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIG-SNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISKNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTMNLITRDYVYNFTYNA---EGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVALDTSNRE-NVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEISLSSEPHIL--------AGAVNPTLGKCNISLPGEHN-----------ANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPI-LWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKTDYDQSGKIISRAWADGKIWSYTYLEKSVMLLLH----SQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDS-STSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFS-EEGLVNARFDYSY--NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMK---HTKIFNANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYK-MDEDGFLRQRGNDIFEYNSNGLLQKAYNKVSG-WTVQYYYDGLGRRVASKSSLGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFEVVIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELENMELTYELLQLQTKTQEWDPGKMILGIQCELQKQLRNFISLDQLPMTPQYNEGRCLEGGKQPRFAAVPSVFGKGIKFAIK-EGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN--TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTT---VEEEKNHVLEMARQRAVAQAWTQEQRRLQEGEEGTRVWTEGEKQQLLGTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTS4-1", "uniprot_id": "TEN1_MOUSE", "id": "Q9WTS4-1", "name": "Teneurin-1", "aln": "-------------------------MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKP-RQSFNSRETLHEYNQE-LRRNYNSQSRKRKDVEKS------------------------TQEIEFCETPPTLCSGYHTDMHSVSR---HGYQLEMGSDVDTETEGAASPDHALRMWIRG-MKSEHSSCLSSRANSALSLTDTDHERKSDGENGF--------------------------------------------KFSPVCCDMEAPADSAQDMQSSPHN-----------------------------------------------------------QFTFRPLPPPPPPPHACTCAR-KPPPTVDSLQRRSMTTRSQPSPAAPAPPTSTQDSV-------HLHNSWVLNSNIPLETR---------------------------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVG-----QIYANGISNGNPGTESMDTTYSPIG--GRVSDKSE-------KKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKSSDDI--QHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSSHGICVKGECHCSTGWGGVNCETP---LPICQEQCSGHGTFLLDTGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIA-HYLDAVR-DGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNIVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQPLFSQHTSRLFYDRIKFLIGKDSTHVVPQDISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLSEKRTLWLPWNQFIVVEKVIMQRIVAD------APSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVSVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPEFILWEQRTVVLQGFEMDASNLGGWSLNKHHIFNPQSGIIHKGNGENMFIS-QQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGKASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIG-SNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISKNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTMNLITRDYVYNFTYNA---EGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVALDTSNRE-NVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEINLSSEPHIL--------AGAVNPTLGKCNISLPGEHN-----------ANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPI-LWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLH----SQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDS-STSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFS-EEGLVNARFDYSY--NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMK---HTKIFNANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKIQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYK-MDEDGFLRQRGNDIFEYNSNGLLQKAYNKVSG-WTVQYYYDGLGRRVASKSSLGQHLQFFYADLANPIRVTHLYNHTSAEITSLYYDLQGHLIAMELSSGEEYYVACDNMGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFEVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIGTWLELFGFQLHNVLPGFPKPELENMELTYELLQLQTKTQEWDPGKMILGIQCELQKQLRNFISLDQLPMTPQYNEGRCLEGGKQPRFAAVPSVFGKGIKFAIK-EGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN--TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTT---VEEEKNHVLEMARQRAVAQAWTQEQRRLQEGEEGTRVWTEGEKQQLLGTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKZ4-1", "uniprot_id": "TEN1_HUMAN", "id": "Q9UKZ4-1", "name": "Teneurin-1", "aln": "-------------------------MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKP-RQSYNSRETLHEYNQE-LRMNYNSQSRKRKEVEKS------------------------TQEMEFCETSHTLCSGYQTDMHSVSR---HGYQLEMGSDVDTETEGAASPDHALRMWIRG-MKSEHSSCLSSRANSALSLTDTDHERKSDGENGF--------------------------------------------KFSPVCCDMEAQAGSTQDVQSSPHN-----------------------------------------------------------QFTFRPLPPPPPPPHACTCAR-KPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQDSV-------HLHNSWVLNSNIPLETR---------------------------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVEG----ELYANGVSKGNRGTESMDTTYSPIG--GKVSDKSE-------KKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDT--QHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETP---LPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIA-HYLDAVR-DGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVVSD------PPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFIS-QQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILEL-------STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIG-SNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNS---EGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNRE-NVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHIL--------AGAVNPTLGKCNISLPGEHN-----------ANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPI-LWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLH----SQRRYIFEYDQPDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDS-STSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFS-EEGLVNARFDYSY--NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMK---HTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYK-MDEDGFLRQRGNDIFEYNSNGLLQKAYNKASG-WTVQYYYDGLGRRVASKSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIK-DGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN--TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTT---VEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UV98-1", "uniprot_id": "A0A8N7UV98_DANRE", "id": "A0A8N7UV98-1", "name": "", "aln": "----------------------------MDEKLYQSLARPHPGLELSYSSSSEE-EDGNLH-HKHYRETHIRADYEPD-RRFTYNSHKVRRKPLEQ--------------------------PQKDFSDPSQTVFPDFQTELHAANQELAYPGGVSAGVPSDPESEGGASPDHALRLWMQE-VKSEHSSCLSSRANSVLSLTDTEQERKSEPEN---------------------------------------------------------------DLPSSPVA-----------------------------------------------------------QFTFRPLPPPPPPPHACTCARPAPAPLPEVVQRSTLPARCQPLDSGNK--AGQDDNG-------QTHNTWALNSNIPLETR---------------------------------HFLFKHGSGSSAIFNAANQNYPLTSSTVYSPPPRPLPRTTLSRPLFSFSKPYRCCNWKCTALSASAITLTLALLLTYIIVVHLLGLPWHLKRVEG----ELYENGMSKEDQPLPGADFTFTPVHLPGLNTTQPD-------KEVIQRGRVIERGEVAVGTQLVQAIPPGLFWRFHITVHHPEYVKFNISLTRDALLGIYGRRNIPPTHTQFDFVKLLDGRQLIKQDSRNVKSP--IAPPRSLLMSALQETGFVEYLDVGTWYLAFYND-GRKMEQVVVYSTPIETIDGCSTNCNGNGECVAGHCHCFTGFLGPDCSKDSCPVLCSGNGDYEKGVCVCHTGWKGAECEVEEGQCIDPTCSNNGECVNGACVCAPAFKGDNCEQVDCKDPLCSGRGVCVRGECVCSAGWGGESCETA---LPACKEQCSGHGTYQTQTGGCVCEQGWSGEDCAIEVCPVPCSPHSVCVAGRCQCEEGWEGTTCDKQPCHPICEEHGECRDGQCVCQPGWEGEHCTIAAHYLDLFDKDACPGLCNGNGRCTLEQSG-WHCVCQSGWSGPGCNVVMETECNDSKDNDSDGLMDCVDPDCCSQQVCASAPLCQGSPDPRDIIQQSHTSYETRPSRQFFERVRFLIGRDSTHILPGDLPFDSSRVCVIRGQVLASDGTPLVGVNVTFQHNPEYGYTLSRQDGSFDLLAVGGISVSLVFQRAPFLSQIRSVWLPWNQFMVLDRVFMERTESK------TPVCDLKNLISPHAVVLSAPLPRFAADCEERGAVLPELQAVQEEVVIPATVLKLSYLSSRAPGYRSLLRVVLTHSTLPLGLAKVHLSVAVQGRQLLKSFPAAPNLIYVFSWNKTDIYGQQVTGLVQAHVSVGYEYESCLDVVLWEKRVAQLQGFELMPSNLGGWTLNHHHVLNLESGILHKGNGENVFIS-QQPLVISTVMGTGVVRAIPCPNCNGPAVEQKLFAPIALACGSDGSVYVGDFNYIRRILPNGFAISILELRNRDIRHSSSPAHKYYLSMDPVRESLYLSDTSSGKLYRLKTLTEPKDLSRNVEVVAGSGEQCTPFHPNQCGDGGKATEAALSNPRGIAVDKHGFIYFVDGSTIRKIDDKGVITTIIG-SNGLTSSQPISCDSRMDISQVRLEWPTDLAVSPLDNSLYVLDNNLVLQVSESQQVRVVAGRPIHCPMASIEPVLLGKTAVRSVLEGAKAIAVSHQGTLYIAETDDRKHSRVQEVSTNGEMVIIAGATSECDCKIDPNCECFSGDGGYARDAKLKSPSSLAVSPNGSLCIADLGNVRIRRLTANHPQLNPEGLYELASVADQELYLFSPNGTHLFTRSLVTGDYLLNFTYTP---EGHLSSIANREGTIAQLRRDANGVPLWLVAPGGQVYWLTISNAGMLKRISALAHDLAQLSYYGNTGLLATISNENGWTSVYEYNSDGHLINVTLPTGEVSSFHGNMEKAVRVEATASNRE-NFIIITNHSADNTMYTLRQAHSVSVYGVRDDGSLWVTYASGMDVSLSTEPAVASGLLAGASAGLVHPTVGRCNITLPGEPA-----------HSLIEWRQRREQAKGNYTAYERRLRAHNRNVLSIDYSQESRVGKIYDDHRKFTLRVQYDDKGRPV-LWTP-SKYNQVRVSYSSEGLVTGIQRGNWTERRDYD-NGRIITRTWANGKIWSYTFLEKSVQLLLH----SQRRYTFEYDQTDCLLSVTLPSMVRHSLQTSLSVGYYRNTYTPPDSPTSSFTQDYAHDGRLLQSLYLGTGRRVIYKYSRVARLAEILYDSTLVTFTYDEATGAVKTIHLMHEGFVCTIRYRQTGPLVSRQIYRFS-EEGLVNARFDYSY--NNFRVTSMQAMINETPLPIDLYRYVDVSGRIEQFGKFSVINYDLNQVITTHAMK---HTKIFNPNGQVIEVQYEILKSIAYWMTLQYDSMGRVTNCDIRIGVDSNITRYAYEYDADGQLQTVAINDRPQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYR-TDEDGFLRLRGNLLFDYGSNGLLMGAYDRDSE-QRVWYRYDGLGRRVASRSSDGAQLQFFYADLMEPTRVTHLYNHSSAEITSLYYDLQGHLIAMEMSSGEEFYIACDNAGTPLAVFSSRGHVVKEVRYTPYGDVYRDSNPTFSLIFGFQGGLYDPFTRLVHLGRRDYDVVAGRWTTPNHELWAELSVN-PKPFNLYAFKNNYPLGHLQDITKFTTDISSWLQLFGFQLHNVVPGFPKPKVENTEQTYEMMATQIRTQTWDTSKIVLGIQCDLQKNLKNFISLDRLPMTPANGKIGGRQG-RRPIFSALSSIFGKGVKFAIR-DGVVATEIIGVASEDSRRVAAVLNSAIYLRGLHFTVEGRDTHYFTKAGPLEADLGVAGGGAGGGVRVLENGVNVSVSQISAMVGGEMRRFADIVLQQGALSFNIRYGAS---PEEERTRVLDAARIRAVQGAWLREQKRVLEGDGGSLAWTDKEKDELIAEGHVSGYDGFYALPVEQHPELADSPFNIHLIRHVETGRR----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61307-1", "uniprot_id": "TENM_DROME", "id": "O61307-1", "name": "Teneurin-m", "aln": "----------------------------MNPYEYESTLDCRDVGGGPTPAHAHPHAQGRTLPMSGHGRPTTDLGPVHGSQTLQHQNQQNLQAAQAAAQSSHYD------------------YEYQHLAHRPPDTANNTAQRTHGRQGFLLEGVTPTAPPDVPPRNPTMSRMQNGRLTVNNPNDADFEPSCLVRTPSGNVYIPSGNLNINKGS---------------------------------------------------------------PIDFKSGSACS----------------------------------------------------------TPTKDTLKGYERSTQGCMGPVLPQRSVMNGLPAHHYSAPMNFRKDLVARCSSPWFGIG----SISVLFAFVVMLILLTTTG----------------------------------VIKWNQSPPCSVLVGNEASEVTAAKSTNTDLSKLHNSSVRAKNGQGIGLAQGQSGLGAAGVGSGGGSSAATVTTATSNSGTAQGLQSTSASAEATSSAATSSSQSSLTPSLSSSLANANNGGAR--------------TFPARSFPPDGTTFGQITLGQKLTKEIQPYSYWNMQFYQSEPAYVKFDYTIPRGASIGVYGRRNALPTHTQYHFKEVLSGFSASTRTARAAHLS--------------ITREVTRYMEPGHWFVSLYNDDGDVQELTFYAAVAEDMTQNCPNGCSGNGQCLLGHCQCNPGFGGDDCSESVCPVLCSQHGEYTNGECICNPGWKGKECSLRHDECEVADCSGHGHCVSGKCQCMRGYKGKFCEEVDCPHPNCSGHGFCADGTCICKKGWKGPDCATMDQDALQCLPDCSGHGTFDLDTQTCTCEAKWSGDDCSKELCDLDCGQHGRCEGDACACDPEWGGEYCNTRLCDVRCNEHGQCKNGTCLCVTGWNGKHCTIE----------GCPNSCAGHGQCRVSGEGQWECRCYEGWDGPDCGIALELNCGDSKDNDKDGLVDCEDPECCASHVCKTSQLCVSAPKPIDVLLRKQ---PPAITASFFERMKFLIDESSLQNYAKLETFNESRSAVIRGRVVTSLGMGLVGVRVSTTTLLEG-FTLTRDDGWFDLMVNGGGAVTLQFGRAPFRPQSRIVQVPWNEVVIIDLVVMSMSEEKGLAVTTTHTCFAHDYDLMKPVVLASWKHGFQGACPDRSAILAESQVIQESLQIPGTGLNLVYHSSRAAGYLSTIKLQLTPDVIPTSLHLIHLRITIEGILFERIFEADPGIKFTYAWNRLNIYRQRVYGVTTAVVKVGYQYTDCTD-IVWDIQTTKLSGHDMSISEVGGWNLDIHHRYNFHEGILQKGDGSNIYLR-NKPRIILTTMGDGHQRPLECPDCDGQATKQRLLAPVALAAAPDGSLFVGDFNYIRRIMTDGSIRTVVKLN------ATRVSYRYHMALSPLDGTLYVSDPESHQIIRVRDTNDYSQPELNWEAVVGSGERCLPGDEAHCGDGALAKDAKLAYPKGIAISSDNILYFADGTNIRMVDRDGIVSTLIGNHMHKSHWKPIPCEGTLKLEEMHLRWPTELAVSPMDNTLHIIDDHMILRMTPDGRVRVISGRPLHCATASTAYDTD--LATHATLVMPQSIAFGPLGELYVAESDSQRINRVRVIGTDGRIAPFAGAESKCNCLERG-CDCFEAEHYLATSAKFNTIAALAVTPDSHVHIADQANYRIRSVMSSIPEASPSREYEIYAPDMQEIYIFNRFGQHVSTRNILTGETTYVFTYNVNTSNGKLSTVTDAAGNKVFLLRDYTSQVNSIENTKGQKCRLRMTRMKMLHELSTPDNYNVTYEYHGPTGLLRTKLDSTGRSYVYNYDEFGRLTSAVTPTGRVIELSFDLS----VKGAQVKVSENAQKEMSLLIQGATVIVRNGAAESRTTVDMDGSTTSITPWGHNLQMEVAPYTILAEQS-PLLGESYPVPAKQRTEIAGDLANRFEWRYFVRRQQPLQAGKQSKGPPRPVTEVGRKLRVNGDNVLTLEYDRETQSVVVMVDDKQELLNVTYDRTSRPISFRPQSGDYADVDLEYDRFGRLVSWKWGVLQEAYSFDRNGRLNEIKYGDGSTMVYAFKDMFGSLPLKVTTPRRSDYLLQYDDAGALQSLTTPRGHIHAFSLQTSLGFFKYQYYSPIN-RHPFEILYNDEGQILAKIHPHQSGKVAFVHDTAGRLETILAGLSSTHYTYQDTTSLVKSVEVQEPGFELRREFKYHAGILKDEKLRFGSKNSLASARYKYAY-DGNARLSGIEMAIDDKELPTTRYKYSQNLGQLEVVQDLKITRNAFNRTVIQDSAKQFFAIVDYDQHGRVKSVLMNVKNIDVFRLELDYDLRNRIKSQKTTFGRSTAFDKINYNADG----HVVEVLGTNNWKYLFDENG--NTVGVVDQGEKFNLGYDIGDRVIKVGDVEFNNYDARGFVVKRGEQKYRYNNRGQLIHSFERERF--QSWYYYDDRSRLVAWHDNKGNTTQYYYANPRTPHLVTHVHFPKISRTMKLFYDDRDMLIALEHED-QRYYVATDQNGSPLAFFDQNGSIVKEMKRTPFGRIIKDTKPEFFVPIDFHGGLIDPHTKLVYTEQRQYDPHVGQWMTPLWETLATEMSH-PTDVFIYRYHNNDPINP-NKPQNYMIDLDSWLQLFGYDLNNMQSSRYTKLAQYTPQASIKS-----NTLAPDFGVISGLECIVEKTSEKFSDFDFVPKPLLKMEPKMRNLLP--RVSYRRGVFGEGVLLSRI-GGRALVSVVDGSNSVVQDVVSSVFNNSYFLDLHFSIHDQDVFYFVKDNVLKLRDDNEELR------RLGGMFNISTHEISDHGGSAAK---ELRLHGPDAVVIIKYGVD---PEQERHRILKHAHKRAVERAWELEKQLVAAGFQGRGDWTEEEKEELVQHGDVDGWNGIDIHSIHKYPQLADDPGNVAFQRDAKRKRRKTGSSHRSASNRRQLKFGELSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : . . . : . . :. . . . : : : . . : : : : .: . .: . : :. : .: .. :: : . .. .:.: : : . ** *: :* : : : * :*. . .* :**: :: : : .*:* *:. *:*:*:.* : :.* : .::: * *.::.*** * * . : : *. .* ***:* * *:* ** * **.. *****. :*:* .* * * **** **.: :* * ..* * * * * .::*. **: ** .* **.:* * * * * ** * * * :*.*** : :: * *: * * **: :* *. *. * . * *: * * *: : *. * :** *::* * * ** *.***: .**. * .:*:* : .. * * * ** *..*. :* * *. **: *** ** **:** . * * . .* ::: . *:::: :* . .* : .*: .:***:*:: * *:**.:: .*::*:** **:: ** :: * * *:** .. : : **. . :: : : * . .:: .: * ::.* *.::*. :.. :.* * ***:.** . ::: :* :* .: :** ::: * : * * .: : : *:: : * *:* *: * *.**::* * :*: :.. *.*.: *::*.*.:: ** : ..**: ** *.* :: ::* :: : ** * *.: *..*.* * ::*:**:*:: **.::***:*::**: . :::: .::*::: .*: :::**..: :: : : * : *.*:*::* * . :****. * :* * *:*:::. ..::*.*.: ** :* ..:::*:: : :*:.*: :.: :::*.***:**:.*:**::::::::::*::: . :* : :***:** .. * ::.* . :::.. * *:::*:*.:: .*:: : *.*.: .** : *:* * *:. * .* :. ::*.. .:. : :** * *:* : . . :* : :*:* * . * * .: * *:* : .: : . . : *: : . .* . : *: ::: * . : ** : . * : .::*: *:* ... *** : . : . : . : . : : : . : :.: . * * * *. .: . :. : . :: : : *:**.:. *:*::::.: : : *.:: *.: ** .:* . * : * * :. : * . * *:: : :.. ::: : * * : * :::* . * ::* * ::: *:*: : * .* . .. : :* . . :* : : :* : . : *::::. :* : : ** .:: . :: : ** ::.: .**:.* * .. *::.:: *.:. ** *:: : *: * . .: : :*: : . :. *:: .: :: . : : :::* .*: . .* : : *: * * : *:* :* ** : :. .. . * **: **: ::*::::. * * : ** : *.. * * ..: * **. .* : : . . *::*:: * :**:: . :. .::** :. *:*:* .. :.:*:* *: *:***.:. * ::*: *.:* : *: * : :.::*** : *:*:: .*:** .*:* :* . :* :..* * . . : *: ** **:.* * .. . . . *:: : . * : .. :.*:*: .: * . . . :.. : : *: *::: . * .:* * . * .*:: . : : :: :** ::*: ::*. * **: ** *:: * * *:: *: ::: * * *::* .:.:. :*:*. *: : :. : :* ", "identical_positions": 480, "similar_positions": 775, "identity": "15.86%" }, { "cls_id": "homologset.agr.FB:FBgn0004456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63258-1", "uniprot_id": "ITA7_RAT", "id": "Q63258-1", "name": "Integrin alpha-7", "aln": "MARIPRCDFLGLPGICYLLSFLLAGLLLPRASAFNLDVMG--AIRKEGEPGSLFGFSVALHRQLQPR---PQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDRGAN-----VQKES----KENQWLGVSVRSQG-----AGGKVVTCAHRYESRQRVDQVLETRDVIGRCFVLSQDLAIR--DELDGGEWKFCEGRPQGHEQFGFCQQGTAATFSPDSHYLIFGAPGTYNWKG--------------------------------------------LLFVTNIDSSDPDQLVYKTLDPADRLTGPAGDLTLNSYLGFSIDSGKGLMRSE-ELSFVAGAPRANHKGAVVILR--KDS-ASRLIPEVVLSGERLTSGFGYSLAVTDLNSDGWADLIVGAPYFFER--QEELGGAVYVYMNQGG--HWADISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK--VFIYHGSSLGVVTKPSQVLEGEAVG--------IKSFGYSLSGGLDVDGNHYPDLLVGSLA-DTAALFRARPVLHVSQEIFIDPRAIDLEQ-PNCADGRLVCVHVKVCFSYVAVP--SSYSPIVVLDYVLDGDTDRRLRGQAPRVTFPGRGPDDLKHQSSGTVSLKHQHDRVCGDTVFQLQEN-VKDKLRAIVVTLSYGLQTPRLRRQAPDQGLPLVAPILNAHQPSTQRTEIHFLKQGCGDDKICQSNLQLAQAQFCSRISDTEFQALPMDLDG-TALFALSGQPFIGLELTVTNLPSDPARPQADGDDAHEAQLLATLPASLRYSGVRTLDSVEKP--LCLSNENASHVECELGNPMKRGTQVTFYLILSTSGITIETTELKVELLLATISEQD---LHPVSVRAHVFIELPLSISGVATPQQLFFSGKVKGESAMRSER------------DVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANG-------KWLLYPMRVELEGG------------------------------------------QGPEKKGICSPRP---NILHLDVDSRDRRRRELGQP---EPQEPPEKVEPSTSWWPVSSAEKR-NVTLDCAQGTAKCVVFSCPLY--SFDRAAVLHVWGRLWNSTFLEEYMSVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPV-AVVAEGVPWWVILLAVLAGLLVLALLVLLLWKLGFFKRAKHPEATVPQYHAVKILREDRQQFKEEKTGTIQRSNWGNSQWEGSDAHPILAADWHPELGPDGHPVSVTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61738-1", "uniprot_id": "ITA7_MOUSE", "id": "Q61738-1", "name": "Integrin alpha-7", "aln": "MARIPRCDFLRPPGIYYLITSLLAGLFLPPAIAFNLDVMG--AIRKEGEPGSLFGFSVALHRQLQPR---PQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDRGAN-----VQKES----KENQWLGVSVRSQG-----AGGKIVTCAHRYESRQRVDQALETRDVIGRCFVLSQDLAIR--DELDGGEWKFCEGRPQGHEQFGFCQQGTAATFSPDSHYLVFGAPGTYNWKGTARVELCAQGSPDLAHLDDGPYEAGGEKEQDPRLIPVPANSYLGLLFVTNIDSSDPDQLVYKTLDPADRLTGPAGDLTLNSYLGFSIDSGKGLMRSE-ELSFVAGAPRANHKGAVVILR--KDS-ATRLIPEVVLSGERLTSGFGYSLAVTDLNNDGWADLIVGAPYFFER--QEELGGAVYVYMNQGG--HWADISPLRICGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK--VFIYHGSSLGVVVKPSQVLEGEAVG--------IKSFGYSLSGGLDVDGNHYPDLLVGSLA-DTAALFRARPVLHVSQEIFIDPRAIDLEQ-PNCADGRLVCVDIKICFSYVAVP--SSYSPSVALDYMLDGDTDRRLRGQVPRVTFLSRGLDDLRHQSSGTVWLKHQHDRVCGDTVFQLQEN-VKDKLRAIVVTLSYGLRTPPLGRQAPGQELPTVAPILNAHQPSTQRTEIHFLKQGCGQDKICQSNLQLERYQFCSRISDTEFQALPMDLDGRTALFALSGQPFIGLELTVTNLPSDPSRPQADGDDAHEAQLLVTLPASLRYSGVRALDSVEKP--LCLSNDSASHVECELGNPMKRGAQVTFYLILSTSGITIETTELEVKLLLATISEQE---LDPVSVRAHVFIELPLSISGVATPQQLFFSGEVKGESAMRSER------------ELGRKVKYEVTVSNQGQSLNTLGSANLNIMWPHEIANG-------KWLLYPMRVELEGG------------------------------------------QGPGKRGICSPRP---NILQLDVDSRDRRRRELGQP---EPQEPPEKVEPSTSWWPVSSAEKR-NMTLDCPR-TAKCVVFSCPLY--SFDRAAVLHVWGRLWNSTFLEEYMAVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPM-AVVVEGVPWWVILLGVLAGLLVLALLVLLLWKLGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTIQRSNWGNSQWEGSDAHPILAADWHPELGPDGHPVPATA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13683-1", "uniprot_id": "ITA7_HUMAN", "id": "Q13683-1", "name": "Integrin alpha-7", "aln": "MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMG--ALRKEGEPGSLFGFSVALHRQLQPR---PQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGAD-----MQKES----KENQWLGVSVRSQG-----PGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIR--DELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAE-ELSFVAGAPRANHKGAVVILR--KDS-ASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFER--QEELGGAVYVYLNQGG--HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK--VFIYHGSSLGVVAKPSQVLEGEAVG--------IKSFGYSLSGSLDMDGNQYPDLLVGSLA-DTAVLFRARPILHVSHEVSIAPRSIDLEQ-PNCAGGHSVCVDLRVCFSYIAVP--SSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN-VKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKP--LCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQE---LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSER------------DVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANG-------KWLLYPMQVELEGG------------------------------------------QGPGQKGLCSPRP---NILHLDVDSRDRRRRELEPP---EQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLY--SFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPM-AVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LL92-1", "uniprot_id": "A0ABK0LL92_RAT", "id": "A0ABK0LL92-1", "name": "Integrin alpha-6", "aln": "MAVAG--------QLCLLY--LSAGLLARLSTAFNLDTREDNVIRKSGDPGSLFGFSLAMHWQLQPE---DKRLLLVGAPRAEALPLQKANRTGGLYSCDITSRGP-CTRIVFDNDAD-----PMSES----KEDQWMGVTVQSQG-----PGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETDHDESLVPVPANSYLGLLFLTSLSYTDPDQFVYKTRPPRERPD-TSPDVMMNSYLGFSLDSGKGIVSKD-DITFVSGAPRANHSGAVVLLK--RDMKSAHLLLEYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDR--DGEVGGAVYVYINQQG--RWSNVKPVRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGK--VFIYHGSPTGIITKPTQVLEGTTP-----------FFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVINILKTITVTPSRIDLRQKSMCGSPSGICLKVKACFEYTAKP--SGYNPPISILGILEAEKERRKSGLSSRVQFRNQGSEP---KYTQELTLNRQKQRACMEETLWLQEN-IRDKLRPIPITASVEIQEPSSRRRVN--SLPEVLPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYKFGTREGNQDKFSYLPIQKG--IPELVLKDQKDIALEITVTNGPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTTEVTFDTTDLDINLKLETTSNQDN--LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSED------------EVGSLIEYEFRVINLGKPLKNLGTATLNIQWPKEISNG-------KWLLYLMKVESKG----------------------------------------------LEQVVCEPHN---EINFLKLKESHNSRKKRELP---EKQIDDSRK--------FSLFSERKYQTLNCSV-NVRCVNIRCPLR--GLDSKASLVLRSRLWNSTFLEEYSKLNYLDILVRASIDVTAAAQNIKLPHAGTQVRVTVFPSKT-VAQYSGIAWWIILLAVLAGILMLALLVFLLWKCGFFKRSRY-DDSVPRYHAVRIRKEEREINDEKHTDNPEKK-WPPKWNENESYS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61739-1", "uniprot_id": "ITA6_MOUSE", "id": "Q61739-1", "name": "Integrin alpha-6", "aln": "MAVAG--------QLCLLY--LSAGLLARLGTAFNLDTREDNVIRKSGDPGSLFGFSLAMHWQLQPE---DKRLLLVGAPRAEALPLQRANRTGGLYSCDITSRGP-CTRIEFDNDAD-----PMSES----KEDQWMGVTVQSQG-----PGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETDHDESLVPVPAN----------------------------------------SYLGFSLDSGKGIVSKD-DITFVSGAPRANHSGAVVLLK--RDMKSAHLLPEYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDR--DGEVGGAVYVYINQQG--KWSNVKPIRLNGTKDSMFGISVKNIGDINQDGYPDIAVGAPYDDLGK--VFIYHGSPTGIITKPTQVLEGTSP-----------YFGYSIAGNMDLDRNSYPDLAVGSLS-DSVTIFRSRPVINILKTITVTPNRIDLRQKSMCGSPSGICLKVKACFEYTAKP--SGYNPPISILGILEAEKERRKSGLSSRVQFRNQGSEP---KYTQELTLNRQKQRACMEETLWLQEN-IRDKLRPIPITASVEIQEPSSRRRVN--SLPEVLPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYKFGTREGNQDKFSYLPIQKG--IPELVLKDQKDIALEITVTNSPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTTEVTFDTTDLDINLKLETTSNQDN--LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSED------------EVGSLIEYEFRVINLGKPLKNLGTATLNIQWPKEISNG-------KWLLYLMKVESKG----------------------------------------------LEQIVCEPHN---EINYLKLKESHNSRKKRELP---EKQIDDSRK--------FSLFPERKYQTLNCSV-NVRCVNIRCPLR--GLDSKASLVLRSRLWNSTFLEEYSKLNYLDILLRASIDVTAAAQNIKLPHAGTQVRVTVFPSKT-VAQYSGVAWWIILLAVLAGILMLALLVFLLWKCGFFKRSRY-DDSIPRYHAVRIRKEEREIKDEKHMDNLEKKQWITKWNENESYS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23229-1", "uniprot_id": "ITA6_HUMAN", "id": "P23229-1", "name": "Integrin alpha-6", "aln": "MAAAG--------QLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPE---DKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDAD-----PTSES----KEDQWMGVTVQSQG-----PGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGLLFLTSVSYTDPDQFVYKTRPPREQPD-TFPDVMMNSYLGFSLDSGKGIVSKD-EITFVSGAPRANHSGAVVLLK--RDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQG--RWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGK--VFIYHGSANGINTKPTQVLKGISP-----------YFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANP--AGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEP---KYTQELTLKRQKQKVCMEETLWLQDN-IRDKLRPIPITASVEIQEPSSRRRVN--SLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG--VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDN--LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSED------------EVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNG-------KWLLYLVKVESKG----------------------------------------------LEKVTCEPQK---EINSLNLTESHNSRKKREIT---EKQIDDNRK--------FSLFAERKYQTLNCSV-NVNCVNIRCPLR--GLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKT-VAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSRY-DDSVPRYHAVRIRKEEREIKDEKYIDNLEKKQWITKWNENESYS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QPM6-1", "uniprot_id": "A0A8M9QPM6_DANRE", "id": "A0A8M9QPM6-1", "name": "", "aln": "--------------MVMLFSLLFTVWIILPARVFVFNLDTQNVMRKRGEADSLFGFSMAMHHQLKPS---DQRVLLIGAPRAKALPVQNANISGGLYRCKFTTQPDDCERIPVDIKAR-----SKDHPGVDYRENQWLGVSVQSQG-----RGGKVVTCAHRYQDWSFTNQR-----LLGRCFVLGQDLVLG--TDG-ADTRSFCRTRETDKHNFGYCQQGLSVAFSKDSKYLVYGAPGAYDWKGIVHMEP----------------------------------------------VEDFSLEIYETADEHELNP-----VDISSFLGFALDTGMNLMKKG-ELNVVAGAPRSNHSGEVLLLRPEDRTEARNLQVEHILRGPGLASSFGYDLTILDLNADGWDDIVVGAPEFSSKNMDDDVGGAVYIYINQAEGQHWSHFQPVCLYGKKDSMFGLAVAHVGDLNQDGYQDFAASAPNEDSGRGRVYIYHGSAAGFHHKPT-ILDAGDHS--------IKLFGYSLAGNMDMDGNGYPELAVGSFS-DTVLIYRTKPVINIEKTLTLTPNKIDFKA-QDCKR-KPCIITAQSCFTYTTEP--QTYNPKLRIEYKLEADTVRRERGLPSRVVFVNSDAAN------GRQQLKAQRQKSCVQTKLRLLGE-IQDKLTSISISLSVSLPSDNPKQTIR--NLPDLEPVLNTLQEKTSKAEVSFLNSGCGSDNICQSNLQLQYSFCTKDQQQDQCDPLAMENG---VPVISPGDVNIALEVTVTN---------TGGDDAHHTQLYVMFPEVLHLTSVVPKKNSVTQ-VQCNPNENRTQADCQLGNPLKRDAEVSFFLMLNTEKLSLRVTSANVTLALKTISIQD---VPIVVAEAKIIFELHLNIIGLAKPSQLFFGGEVKDEKAMKAED------------DVGSLVQYEFRIFNIGRPLKSFGSAVLNIQWPKATKAG-------KRLLYLMQITDRG----------------------------------------------KNIIHCTPSE---AINTLRFNMASSRGKRELER---ESGLKALAS---TSDFFPFLGNKRKYKTLTCAD-ELSCVELRCPLE--ALDSSAVILLHARLWNNTFLQEYSSLNYLDIILNASLTLNGTQGNIGMQPSDTKVKLTVFAERR-PALLSRVPWWLILLSVVTALLLLALLFYLLWKFECLT-----------CGACAKQKEV--------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZCG9-1", "uniprot_id": "D3ZCG9_RAT", "id": "D3ZCG9-1", "name": "Integrin alpha-3", "aln": "-MGPGPRRVPRDPGWMLRALALMVAASGRVAFAFNLDTKFL-VVKEAVNPGSLFGYSVALHRQTERQ---QRYLLLAGAPRDLAVDDDYTNRTGAVYLCPLTALKNDCERMDIS---------EKSDPDHHIIEDMWLGVTVASQG-----PAGRVLVCAHRY-TKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSN-TDYLQTGMCQLGTSGGFTQN--TVYFGAPGAYNWKGNSYMIQR----------------------------------------------KDWDLSEYSYRGSED---------QGNLYIGYTMQVGSAILHPS-EITLVTGAPRHQHMGAVFL---LKQESGGDLQRRQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER--KEEVGGAVYVFMNQAGT-SFPDQPSLLLHGPSRSAFGISVASIGDINQDGFQDIAVGAPFEGLGK--VYIYHSSSGGLLKQPQQIIHGETLGLPG-----LATFGYSLSGKMDVDENLYPDLLVGSLS-DHIVLLRARPVINILHRTLVARPAVLDPSLCTVTS----CVQVELCFAYNQSAGNPNYRRNITLAYTVEADRDR----RPPRLRFARSQSSV------FHGFFSM-PETHCQTLELLLMDN-VRDKLRPIVITMNYSLPLRMPDRLKLGLRSLDAYPVLNQAQAMENHTEVHFQKE-CGPDNKCDSNLQMRAAFVSEQ------------LQPLSRLQYSRDTKKLFLSINVTNSPSR----QRAGEDAHEALLTLEVSSALLLSSVRP---------AGTCQANETNTVCELGNPFKRNQRMELLIAFEVTGVTLHTRDLRAHLQLSTSSHQDN--LQPMFLTLQVDYTLQASLSLMNHRLQSFFSGTVMGEAAMKTVK------------DVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEVTNG-------KWLLYPTEITIHS----------------------------------------------NGSWPCQPHGNLVNPLNLTLSDPGVKPLSPQRR---RRQLDPGGDQGPPPVTLAAAKKAKSETVLTCSNGRARCVWLECPLP--DASNITNVTVKARVWNSTFIEDYKDFDRVRVDGWATLFLRTSIPTINMENKTTWFSVDIDSELV-EELPAEIELWLVLVAVGAGLLLLGLIIILLWKCGFFKRA----RTRALYEAKRQKAEMRSQPSETERLTDDY------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62470-1", "uniprot_id": "ITA3_MOUSE", "id": "Q62470-1", "name": "Integrin alpha-3", "aln": "-MGPGPCRVPRAPGWLLRALALMVAACGRVAFAFNLDTRFL-VVKEAVNPGSLFGYSVALHRQTERQ---QRYLLLAGAPRDLAVGDDYTNRTGAVYLCPLTAHKDDCERMDIS---------EKSDPDHHIIEDMWLGVTVASQG-----PAGRVLVCAHRY-TKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSN-TDYLQTGMCQLGTSGGFTQN--TVYFGAPGAYNWKGNSYMIQR----------------------------------------------KDWDLSEYSYRGSEE---------QGNLYIGYTVQVGNAILHPTDIITVVTGAPRHQHMGAVFL---LKQESGGDLQRKQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER--KEEVGGAVYVFMNQAGA-SFPDQPSLLLHGPSRSAFGISIASIGDINQDGFQDIAVGAPFEGLGK--VYIYHSSSGGLLRQPQQIIHGEKLGLPG-----LATFGYSLSGKMDVDENLYPDLLVGSLS-DHIVLLRARPVINILHRTLVARPAVLDPALCTATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDR----RPPRLRFARSQSSV------FHGFFSM-PETHCQTLELLLMDN-VRDKLRPIVIAMNYSLPLRMPDRLKLGLRSLDAYPVLNQAQAMENHTEVHFQKE-CGPDNKCDSNLQMRAAFLSEQ------------LQPLSRLQYSRDTKKLFLSINVTNSPSS----QRAGEDAHEALLTLEVPSALLLSSVRP---------SGTCQANNETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLPVLLQLSTSSHQDN--LQPVLLTLQVDYTLQASLSLMNHRLQSFFGGTVMGEAAMKTAE------------DVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEVTNG-------KWLLYPTEITIHS----------------------------------------------NGSWPCQPSGNLVNPLNLTLSDPGVTPLSPQRR---RRQLDPGGDQSSPPVTLAAAKKAKSETVLTCSNGRARCVWLECPLP--DTSNITNVTVKARVWNSTFIEDYKDFDRVRVDGWATLFLRTSIPTINMENKTTWFSVDIDSELV-EELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRA----RTRALYEAKRQKAEMKSQPSETERLTDDY------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26006-2", "uniprot_id": "ITA3_HUMAN", "id": "P26006-2", "name": "Integrin alpha-3", "aln": "-MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFL-VVKEAGNPGSLFGYSVALHRQTERQ---QRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNIT---------VKNDPGHHIIEDMWLGVTVASQG-----PAGRVLVCAHRY-TQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSN-TDYLETGMCQLGTSGGFTQN--TVYFGAPGAYNWKGNSYMIQR----------------------------------------------KEWDLSEYSYKDPED---------QGNLYIGYTMQVGSFILHPK-NITIVTGAPRHRHMGAVFL---LSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER--KEEVGGAIYVFMNQAGT-SFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGK--VYIYHSSSKGLLRQPQQVIHGEKLGLPG-----LATFGYSLSGQMDVDENFYPDLLVGSLS-DHIVLLRARPVINIVHKTLVPRPAVLDPALCTATS----CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDR----RPPRLRFAGSESAV------FHGFFSM-PEMRCQKLELLLMDN-LRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ------------QQKLSRLQYSRDVRKLLLSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVRP---------PGACQAN-ETIFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDN--LWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVE------------DVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNG-------KWLLYPTEITVHG----------------------------------------------NGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRR---RRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELV-EELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRA----RTRALYEAKRQKAEMKSQPSETERLTDDY------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YWS7-1", "uniprot_id": "A0A8M6YWS7_DANRE", "id": "A0A8M6YWS7-1", "name": "", "aln": "--------MIVFHRKGLRLTLVFVLSAARLCQAFNLDVSFA-VVKEGKTAGSLFGLSVALHEQVVNE---KRHMLLVGAPKEKAESGLSANETGDVYACPISADSKDCARLNLISSNPE----DKPDLKNYVIDGMWLGVSIVSQSQ----PGGRVVACGHRY-IRNFTSN----FRMIGRCYVRGNDLQLNLSDYQWQSYDEICDPR-EAQNSEGMCLLGMSAAVTFS--EIFFGAPGCFNWQGNIFSKWHN-------------------------------------------PADEFHLLKSKLPDSR----------KGNIYIGYSTIVDQDVLVKG-KDTVVTGAPRDEAKGSVMMAEVLKSGGSGEVKIKVTVTGEQVGSYFGNSVAVVDLNNDGWKDLIVGAPFYFDR--KMDKGGAVYVYMNQNG--SFRNKSDVVLTGPKDSGFGMSVVAIGDVNQDGFQDFAVGAPYHSTGR--VSIWTGSKTGISQEPSQVIDGKDIPGGG-----FQTFGYSISRGLDVDRNGYPDIAVGSLD-DRVVLLRSRPVIHLKN-TFTVTPMVIN--LEDCVA----CIEAKVCFSYTYSTGTASSQKAVTLQYTVEADQQSS---RSPRVSFLDNNKGK------YTGKMSVNPSGDCHSLKLELASKTIQDKVSAIIFQLSVSVVDPPPSGGKM-LEDLSAFPVISQRDALTGRAEIHIQKA-CGLDNKCESNLQMTAAFTDEKNTP------FLMQEDHQIFNYTTDIKKLKLLVNVSNVPSE----GRKAEDAYNAILNITIPSSLSFSSLNPK---LPSTLNGDPSSGGSYLLCTLGDPFKSNQRVEIEITFETSGISIDMQEIETELQLSTLSDQND--LRPLSRVLLVEYILQPLFNLIPY-FRAEFSGNVVGESAMKSTS------------DIGSPVEFNISVDISGKPLGNLGFLEVVFQWPSAVANE-------KWLLYLSEIQMTG----------------------------------------------TSESFCVAKG-IVNPLNLTVSER----KSRRRK---RDEVLSESKLAMSQKTRQGQNKPR--EVLNCTKGTARCQTFSCPLS--AMKTSAMLTVRARVWNSTMLEDYRAKG-VSVQGSVMLTLKTDKKNIKMNNNIREFTVEIDPAVA-EELPYEAPLWIIIVSVLSGVVMLGVIVILLWKSGFFTRIDY-FRAMPKYKGVRICKKEQYQVNQGFLILDTTNNRKHWITSWTEKKQYY-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24247-1", "uniprot_id": "ITA1_DROME", "id": "Q24247-1", "name": "Integrin alpha-PS1", "aln": "MLELPFTTIRPNCRLRQNLGILIILQCVLTCYNFNLEQRLP--IVKYGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQ-PNTTHSGALWRCPMTQRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYG-----QGLCYLLTNDLQFE-----EVHEPCKGRPVQRQHEDYGLCQAGTSAALLDD-DTMVLGSPGPYTWRGSIWVTQVGG------------------------------------------EYLQRDKTTYYSDHSDLNSP-----VDKYSYLGMSVTGGRFFGHMS----YAAGAPRSEGHGQVVIFD---KSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTK----TEGGAVYVYQNIQDT--LPMKYTLKLTGPLESRFGLALANIGDLNKDNCEDLAVGAPYEGNGV--VYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISGNTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASNLTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRT-------NVLSRVVRVHTNGRTECQAVTGYIKANTRDIQTPVRFRLKYSLVEPPLADSALVRLNPILDQTQAHVDFEGT--FQKDCGDDDLCESNLIIRVEPNITESSG-------------NEYTLILDETELEVRINVSN----------LADSAYEAQLFIAHQAGVSYVATKKPTN------ATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKIMLFHIFANTTSKLVGPERPERDLRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGP--STAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAANGKKQDIVELDCNKGATNCVRIECDILNMPALSEAQVVVKARLWNSTLVSEYPRVERVRIFSTATAQIPESYGVEVMDHNNIEVETRAYPELRNQQRDTSIPWLIIILGIVGGLLLLALVTYVLWKVGFFKRIRP--TDPTLSGNLEKMNEEKPFLAPSKNTHHVF------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :: : : . * ** *:* * :* *** :. :* :: * :: * :: :. *:**:: *: .*:::.*.*** . * *:: ::* : . * * * : . . : *:** : *:* ::* : . . .:**** . * *.: : . . * . : ** :: *:* * *:::.** : : ***:*:: * : : * * **::: :**:*:*. *:*..** .. * * *: .* *. :* :.. ** *:: *:* * **:: :*:: . : ::*:: : : : : ::.: . * :: : * : *::. : : ** *. *:*** : . : : : *:* .:.*:.: * : . . . * **:*: . . : :. : : * * : . : :.* : .: ::* :.. . : * : : ** : *** .: . : * * * : * : : : : .*:**.*::.:* : : . : : . ::::.: .:::*.:: :*** :. : ", "identical_positions": 124, "similar_positions": 207, "identity": "9.54%" }, { "cls_id": "homologset.agr.FB:FBgn0004463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L8N3-1", "uniprot_id": "A0ABK0L8N3_RAT", "id": "A0ABK0L8N3-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "-------------MDVLAEEFGSLTP-----EELAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLAKYNE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59470-1", "uniprot_id": "RPC2_MOUSE", "id": "P59470-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "-------------MDVLAEEFGSLTP-----EQLTAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLAKYNE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NW08-1", "uniprot_id": "RPC2_HUMAN", "id": "Q9NW08-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "-------------MDVLAEEFGNLTP-----EQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQA2-1", "uniprot_id": "F1QQA2_DANRE", "id": "F1QQA2-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "---------------MLQEEFGEMSP-----QQLAAPVDTVEEKWKLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKITSDADPMWYLKYLNIYVGMPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPMEFSKLNECPLDPGGYFIVKGQEKVILIQEQLSKNRIIVDQDRK-GTVGASVTSSTHEKKSRTNMIVKQGRFYLKHNTLSEDAPIAIIFKAMGVESDQEIVQMIG-TEEHVMAAFAPSLEECQKAQIFTQTQALRYIGNKVRRQRMWGG-PKKTKMEEARELLASTILTHVPVKEFNFRAKCIYLAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSELKKIADQIIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSFISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAFNLGVEDVNLLCGEELSYPTVFLVFLNGNILGVIRDHQKLVYTFRLMRRAGFINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKNGKPAVKNKHIEELSQGYRTFEDFLHESLVEYLDVNEENDCNIALYEHMISKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQRPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLRRYTNQTFDKVMGPMLDAETRKPIWRHSILDADGICSPGEKVENKQVLVNKSMPTVTQT-PLEGSAQPGQPQYREVPVSYKGATDSYIEKVMISSNAEDAFLVKILLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGYPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLIRYGYNYQGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLARYNE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25167-1", "uniprot_id": "RPC2_DROME", "id": "P25167-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "MVELKMG-----DHNVEATTWDPGDS-----KDWSVPIKPLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYLDVRVGKPDIDDGFNITKATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCSNCALTGKSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNKMLT-EDFN-GVVQCQVTSSTHEKKSRTLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLIG-IDSKSQNRFGASLIDAYNLKVFTQQRALEYMGSKLVVKRFQSA-TTKTPSEEARELLLTTILAHVPVDNFNLQMKAIYVSMMVRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPK-VKAAQFDVVK--HMRAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNPINNPNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRPYVIVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIEPFTLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELTNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGPMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPLQGQS--AQVPYTAVPISYKGPEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDFGICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELERHGFNYVGKDFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEMERDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMPYACKLLFQELTSMNVVPKMILENY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22276-1", "uniprot_id": "RPC2_YEAST", "id": "P22276-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKK--SSSSTKDYLTPPHECRLRDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQALEYIGAKVKTMR----RQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVEDITLIDSASLHLN--YGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRCETRRKTTTVLKRYANHTQD-IIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQIYINKSVPTNSAD-APNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLEDIFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :. : : . :**:*:****:********:****:*::.::***:***: : *..** :****::: ** ... . ..******** ****** ******** : * :: : *****:***..:* * . :::*************:*.* *****:***** *:::. * : * * ..*******:**:* : *:*: **:**::::: **.:::** *: ** ** .:: :. *. .* :. : .::** :**.*:* *: * . * :*. * : :*:::*:.*. :::: *.:* ::*.***: * : .***** *********.*:*::******::* ::* *: : * :* ::*.: ::: :** *: ***:***::*****:* ***:******:*********:.*****:*******:*****:****.:**********************: *: *: :. ****: : . : : *::**.::* ::* :* :** * :..::*: :. : .::* :****:*** :**.. :. *.: *: :* * *:*** .*:**********. ** *. * *********:**. ***:*********************:* *.*** :***:*:* :.**: ****:***** :::************************:***:*:***:*** . :::. .::**:*:* * ::* * . . *::*. *..**: * :*:. *: :**.:*: : . : . * * .*: *:*. *:*::**:* . :: *:*:****.* **:************* *:** ****** * ** **:******:******** :**:.****:*:* :.***.*****::*: * *:** *** . ***** *:***: **:********* **********:********:****:************:*.**** *::*************** ** :.*..** *:*: :: .: :***.******* ***: *:: * ", "identical_positions": 587, "similar_positions": 299, "identity": "50.65%" }, { "cls_id": "homologset.agr.FB:FBgn0004465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWM0-1", "uniprot_id": "PGES2_MOUSE", "id": "Q8BWM0-1", "name": "Prostaglandin E synthase 2", "aln": "---MAQAARLSW------VLVSSRCALTEGLLTRPWQPLSAQSRAGFTRVAAG-SRGAAVR--KGSPRLLGAAALALGGALGLYHTVRWHQRSQDLRAERSA------------AQLPLSNSLQLTLYQYKTCPFCSKVRAFLDFHSLPYQVVEVNPVRRTEIKFSSYRKVPILVAQEGD-SLQQLNDSSVIISALKTYLVS-GQPLEEVITYYPPMKAMNDQGKEVTEFCNKYWLMLDEKEAQQMYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPAEALASFDYIVREGK----FGAVEAAMAKYVGAAAMYLISKRLKSRHHLQDDVRVDLYEAANKWVTAVGK-DRPFMGGQKPNLADLAVYGVLRVMEGLEAFDDLMRHSHIQPWYLRMERAIEEAPSVHHVN------PSCKD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AE56-1", "uniprot_id": "D4AE56_RAT", "id": "D4AE56-1", "name": "Prostaglandin E synthase 2", "aln": "---MAQAARVAW------VLGSSRCALSEGLLTRPWTQLSAQSRAGFTRAAAG-NRGASIR--KGSPRLLGVAALALGGALGLYHTVRWHLRSQDLHAERSA------------VQLSLSNRLQLTLYQYKTCPFCSKVRAFLDFHSLPYQVVEVNPVRRTEIKFSSYRKVPILVAQEGD-SLQQLNDSSVIISALKTYLVS-GQPLEEIITYYPPMKAMNDQGKEVTEFGNKYWLMLDQKEAQQMYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPAEALASFDYIVREGK----FGAVEATMAKYVGAAAMYFISKRLKSRHHLQDDVRVDLYEAANKWVTAVGK-DRPFMGGQKPNLADLAVYGVLRVMEGLEAFDDLMRHSHIQPWYLRMERAIKEASSMHYLMFMFSPVPALHREQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H7Z7-1", "uniprot_id": "PGES2_HUMAN", "id": "Q9H7Z7-1", "name": "Prostaglandin E synthase 2", "aln": "---MDPAARVVR------ALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAAR--KGSPRLLGAAALALGGALGLYHTARWHLRAQDLHAERSA------------AQLSLSSRLQLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGE-SSQQLNDSSVIISALKTYLVS-GQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGK----FGAVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGK-DRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUC7-1", "uniprot_id": "PGES2_DANRE", "id": "Q7ZUC7-1", "name": "Prostaglandin E synthase 2", "aln": "---MAAACTRTLGKVGRLVLDTPTCRFTNTAAFVPRTSMRCQGRAYGTGSSGFKSRLLLAAPVRGSGRVLG-CAFLLGGGFGLYQTIKLTLQHH--LAEKES------------DASDLDTDLKLTLYQYKTCPFCSKVRAFLDYHRLPYEIVEVNPVMRQEIKWSTYRKVPILMVN----GTVQLNDSSVIISALKTYISSKDKKISEILACYPEMKSKNDRGKDVIEFGNKYWVMVHDADADQLYPGKDSRKEEIKWRTWADDWLVHLISPNVYRTPTEALASFDYIVREGK----FGSFEGFFAKYFGAAAMWIISKRLKYKHNLQADVRQDLYKAVNDWVAAIGK-NKQFMGGDEPNLADLAVFGVLRVMEGLQSFDDMMEHTKVKKWYSRMQKATQHVS-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V420-1", "uniprot_id": "Q9V420_DROME", "id": "Q9V420-1", "name": "", "aln": "MSCIRLASATVLAGVRPPPAASGGGALRLLTKRNPDAAFARRQFAVAVENGGGRKKPNGTFKLAVLGATVGAATGSVYTMYQRWTDGSSHKEHEETKPTRLDGIPAGVRITKRYVNPKDTSGLDIVLFQFQTCPFCCKVRAFLDYMGISYAVVEVDAVLRQDIRWSSVKKVPMVLIRQQDGKYVQMVDSSAIISLIATHLQDKRTDIGELAQFYPHTSFFDDDGKKKNDILNKYFLMYREHTPKGVS--KETDETDRKWRSWADSHLVHLISPNCYQTMGESLETFEWFSQAGEWDVHFPKWERDLMVYCGATAMWAIAKMLKRRHALSDDVRSHMYDALDQWTTELKKRNTKFMGGKQPSLADLSVFGVLSSMEGCQTFKDCLQNTSIGKWFYDVKALVEKNRGQLQRERIENMAAIA----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. . : * : : * . .. . :* .: : : . . . : . *.:.*:*::*****.*******: :.* :***:.* * :*::*: :***::: . *: ***.*** : *:: . : *: ** . :: **. :: ***::* : .. : *:: : *** ***. ******** *:* *:* :*::: : *: * * . * **:**: *:* ** :* *. :** .:*.* :.*.: : * : ****.:*.****:*:*** *** ::*.* :.:: : *: :: . ", "identical_positions": 106, "similar_positions": 107, "identity": "25.06%" }, { "cls_id": "homologset.agr.FB:FBgn0004507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09811-1", "uniprot_id": "PYGL_RAT", "id": "P09811-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAG------TKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKR-INMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLADLIAEKIG---EDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPNQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQEKVSQLYMNQK-AWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET01-1", "uniprot_id": "PYGL_MOUSE", "id": "Q9ET01-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQTG------TKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGMGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWAKAWEITKKTFAYTNHTVLPEALERWPVELVEKLLPRHLEIIYEINQKHLDRIVALFPKDISRMRRMSLIEEEGGKR-INMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLADLIAEKIG---EDYVKDLSQLTKLHSFVSDDIFLREIAKVKQENKLKFSQFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLITSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPNQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQEKVSQLYMNQK-AWNTMVLKNIAASGKFSSDRTIKEYAKDIWNMEPSDLKISLSNESSNGVSANGK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06737-1", "uniprot_id": "PYGL_HUMAN", "id": "P06737-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTG------TKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKR-INMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLAELIAEKIG---EDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYK-VKIN-----PSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPKQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQDKVSQLYMNPK-AWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSNES-NKVNGN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H0W7-1", "uniprot_id": "A0AC58H0W7_DANRE", "id": "A0AC58H0W7-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "---------------MFITIYGLIRMATPLTDQEKRKQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALSHTVRDHLVGRWIRTQQFCYEADPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQ-------------LGLDMEDLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIKDGWQVEEADDWLRYGNPWEKARPEFMLPVHFYGRVEEEEGKE-----PKWVDTQVVLAMPYDTPIPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKTSKRNTSGPLS--FDSFPDKVAIQLNDTHPAMAIPELMRIFVDIEKLDWDTAWDITKRTFAYTNHTVLPEALERWPVDLMEKLLPRHLQIIYKINLIHLNHIASLFPEDMDRIRRMSLIEEGGGKR-VNMAHLCIVGSHKVNGVAKIHSDIIKRDVFQDFSELE-PEKFQNKTNGITPRRWLLLCNPGLADLIAEAIG---EEYVKDLTQLQKLNDLVDDEAFIRDVAKVKQDNKLKFAHYLEKIYK-VDIN-----PASMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------SHPTKPFIPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPVIGRKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVNDVAELDKKGYNALQYYENLS-ELKRAINQIKSGYFSPKQPEMFSDIINMLFHH-DRFKVFADYESYVKCQDRVSALYKDQR-EWTRVVIKNIAASGKFSSDRTITEYATEIWGVEPTDLKIPPPGEPREALEETARSLRKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CI94-1", "uniprot_id": "PYGB_MOUSE", "id": "Q8CI94-1", "name": "Glycogen phosphorylase, brain form", "aln": "-------------------------MAKPLTDSERQKQISVRGIAGLGD--------------VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDG------VLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSRFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELE-PEKFQNKTNGITPRRWLLLCNPGLAEIIVERIG---EGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYK-VKIN-----PASMFDVHVKRIHEYKRQLLNCLHIITLYNRIK---------KDPAKAFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAREFYERLP-ELRQAVDQISSGFFSPKDPDCFKDVVNMLMYH-DRFKVFADYEAYIQCQAQVDRLYRNSK-EWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNLPKD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53534-1", "uniprot_id": "PYGB_RAT", "id": "P53534-1", "name": "Glycogen phosphorylase, brain form", "aln": "-------------------------MAKPLTDSERQKQISVRGIAGLGD--------------VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNG------VLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELE-PEKFQNKTNGITPRRWLLLCNPGLAEIIVERIG---EGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYK-VKIN-----PCSMFDVHVKRIHEYKRQLLNCLHIITLYNRIK---------KDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAQEFYERLP-ELRQAVDQISSGFFSPKDPDCFKDVVNMLMYH-DRFKVFADYEAYIQCQAQVDHLYRNPK-DWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11216-1", "uniprot_id": "PYGB_HUMAN", "id": "P11216-1", "name": "Glycogen phosphorylase, brain form", "aln": "-------------------------MAKPLTDSEKRKQISVRGLAGLGD--------------VAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDG------VKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELE-PEKFQNKTNGITPRRWLLLCNPGLADTIVEKIG---EEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIK---------RDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLP-ELKQAVDQISSGFFSPKEPDCFKDIVNMLMHH-DRFKVFADYEAYMQCQAQVDQLYRNPK-EWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG19-1", "uniprot_id": "A4IG19_DANRE", "id": "A4IG19-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "-------------------------MSKPLTDHERRKQISVRGIAGLGD--------------VAEIKKSFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQYYYEKDPKRIHYLSLEFYMGRTLQNTMINLGLQNTCDEAIYQ-------------LGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMASLGLAAYGYGIRYEFGIFNQKIAHGWQIEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTHDG------PKWVDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFNLQEFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTSFETFHEKVAIQLNDTHPALAIPELMRILVDIEHLDWEKAWEITTKTCAYTNHTVLPEALERWPVYMFEKLLPRHLQIVYEINRRHLDRISALYPGDTDRLRRMSLIEEGDPKR-INMAHLCVVGSHAVNGVARIHSDIVKTTVFKDFCDIE-PEKFQNKTNGITPRRWLLLCNPGLADIIAEKIG---EDFLTDLFQLRKLLDFINDEMFIRDVAKVKQENKQKFAAYLENEYN-VKIN-----PESIFDIQVKRIHEYKRQLLNCLHIITLYNRIK---------KEPNKKFVPRTVMIGGKAAPGYHMAKMIIKLITSVGEVVNHDPVVGDRLKVIFLENYRVSLAEKVVPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVQDVEDMDKKGYNAREYYERLP-ELKLVMDQISTGFFSPKEPELFKDVVNMLMDH-DRFKVFADYESYISCQDKVNELYKNPK-EWTKKVIRNIAASGKFSSDRTIAEYAREIWGVEPSDVKIPPPNEPRE------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WUB3-1", "uniprot_id": "PYGM_MOUSE", "id": "Q9WUB3-1", "name": "Glycogen phosphorylase, muscle form", "aln": "-------------------------MSRPLSDQDKRKQISVRGLAGVEN--------------VSELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQG------AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGSRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELE-PHKFQNKTNGITPRRWLVLCNPGLAEVIAERIG---EDYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFSAYLEREYK-VHIN-----PNSLFDVQVKRIHEYKRQLLNCLHIITLYNRIK---------REPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVERLDQRGYNAQEYYDRIP-ELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHH-DRFKVFADYEEYIKCQDKVSELYKNPR-EWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKI-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09812-1", "uniprot_id": "PYGM_RAT", "id": "P09812-1", "name": "Glycogen phosphorylase, muscle form", "aln": "-------------------------MSRPLSDQDKRKQISVRGLAGVEN--------------VSDLKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVDRWIRTQQHYYAKDPKRIYYLSLELYMGRTLQNTMVNLALENACDEATYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQG------AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPPYFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDKFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELIRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELE-PHKFQNKTNGITPRRWLVLCNPGLAEVIAERIG---EEYISDLDQLRKLLSYLDDQAFIRDVAKVKQENKLKFSAYLETEYK-VHIN-----PNSLFDVQVKRIHEYKRQLLNCLHIITLYNRIK---------REPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPAVGDRFRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEDNFFIFGMRVEDVERLDQRGYNAQEYYDRIP-ELRQIIEQLSSGFFSPKQPDLFKDIVNMVMHH-DRFKVFADYEEYIKCQDKVSELYKNPR-EWTRMVIRNIATSGKFSSDRTIAQYAREIWGLEPSRQRLPAPDEKI-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11217-1", "uniprot_id": "PYGM_HUMAN", "id": "P11217-1", "name": "Glycogen phosphorylase, muscle form", "aln": "-------------------------MSRPLSDQEKRKQISVRGLAGVEN--------------VTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQ-------------LGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQG------AKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERMDWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELE-PHKFQNKTNGITPRRWLVLCNPGLAEVIAERIG---EDFISDLDQLRKLLSFVDDEAFIRDVAKVKQENKLKFAAYLEREYK-VHIN-----PNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIK---------REPNKFFVPRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDKLDQRGYNAQEYYDRIP-ELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHH-DRFKVFADYEDYIKCQEKVSALYKNPR-EWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEAI-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXT3-1", "uniprot_id": "E7EXT3_DANRE", "id": "E7EXT3-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "-------------------------MSKPLTDQEKRKQISVRGLAGVEN--------------VADLKTNFNRHLHFTLVKDRNVATKRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRVYYLSLEFYMGRTLQNTMVNLALENACDEAIYQ-------------LGLDMEELQDIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVKGWQVEEADDWLRYGNPWEKARPEYMRPVHFYGRVEHHPDG------VKWVDTQVVLALPYDTPVPGYRNNIVNTMRLWSAKAPCEFHLKDFNVGGYIQAVLDKNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTEIVRMDLSTLPDKVAIQLNDTHPAMAIPELMRILVDDEKLTWDVAWDITVRTCAYTNHTVLPEALERWPVDLFQNLLPRHLEIIYEINRRHMERISALYPGDFDRLRRMSLIEEGGQKK-INMAHLCIVGSHAVNGVAQIHSDIIKDTVFKDFYDVD-PQKFQNKTNGITPRRWLVMCNPGLAEVIAERIG---EDYIRDLSQLKKLLKFVDDDALIRDIAKVKQENKMKFAVHLEEQYK-VKIN-----PNSMFDVHVKRIHEYKRQLLNCLHIITLYNRIK---------KEPNKAWTPRTIMIGGKAAPGYHTAKMIIKLITSIGDVVNNDIVVGDRLKVIFLENYRVTLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVKDVEAMDKKGYDAMEYYNRIP-ELKQAMDQISGGYFSPADPDQFKDIVNMLMHH-DRFKVFADYEDYIQCQDKVSALYKNTK-EWTKMVIHNIAGCGKFSSDRTISQYAREIWGMEPSLEKIAAPDDSR-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XTL9-1", "uniprot_id": "PYG_DROME", "id": "Q9XTL9-1", "name": "Glycogen phosphorylase", "aln": "-------------------------MSKPQSDADRRKQISVRGIAEVGN--------------VTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMVGRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQ-------------LGLDIENLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARPEFMLPVNFYGRVIDTPEG------KKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFNDGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRNTFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKR-INMAHLSIVGSHAVNGVAAIHSQILKDSLFHDFYEME-PQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIG---DEWPVHLDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYG-VKIN-----PSSMFDIQVKRIHEYKRQLLNCLHIITLYNRIK---------KDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMTVDEVEALKKKGYNAYDYYNANP-EVKQVIDQIQGGFFSPGNPNEFKNIADILLKY-DHYYLLADYDAYIKAQDLVSKTYQNQA-KWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAPEDQPQN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06738-1", "uniprot_id": "PHSG_YEAST", "id": "P06738-1", "name": "Glycogen phosphorylase", "aln": "MPPASTSTTNDMITEEPTSPHQIPRLTRRLTGFLPQEIKSIDTMIPLKSRALWNKHQVKKFNKAEDFQDRFIDHVETTLARSLYNCDDMAAYEAASMSIRDNLVIDWNKTQQKFTTRDPKRVYYLSLEFLMGRALDNALINMKIEDPEDPAASKGKPREMIKGALDDLGFKLEDVLDQEPDAGLGNGGLGRLAACFVDSMATEGIPAWGYGLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWEIERNEVQIPVTFYGYVDRPEGGKTTLSASQWIGGERVLAVAYDFPVPGFKTSNVNNLRLWQARPTTEFDFAKFNNGDYKNSVAQQQRAESITAVLYPNDNFAQGKELRLKQQYFWCAASLHDILRRFKKSK--------RPWTEFPDQVAIQLNDTHPTLAIVELQRVLVDLEKLDWHEAWDIVTKTFAYTNHTVMQEALEKWPVGLFGHLLPRHLEIIYDINWFFLQDVAKKFPKDVDLLSRISIIEENSPERQIRMAFLAIVGSHKVNGVAELHSELIKTTIFKDFVKFYGPSKFVNVTNGITPRRWLKQANPSLAKLISETLNDPTEEYLLDMAKLTQLGKYVEDKEFLKKWNQVKLNNKIRLVDLIKKENDGVDIINREYLDDTLFDMQVKRIHEYKRQQLNVFGIIYRYLAMKNMLKNGASIEEVAKKYPRKVSIFGGKSAPGYYMAKLIIKLINCVADIVNNDESIEHLLKVVFVADYNVSKAEIIIPASDLSEHISTAGTEASGTSNMKFVMNGGLIIGTVDGANVEITREIGEDNVFLFGNLSENVEELR---YNHQYHPQDLPSSLDSVLSYIESGQFSPENPNEFKPLVDSIKYHGDYYLVSDDFESYLATHELVDQEFHNQRSEWLKKSVLSVANVGFFSSDRCIEEYSDTIWNVEPVT-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. :. *: : : . . :.: * *:. **.:. . : * : :::*::* * :*** ***::***** ***:* *:::*: :: : * : **:.:*:: : * ****************:****: *:.*:***:***:*** *** * *:* .* **. ***** * * ** *** * *:. : *:*:.** *:**: .. **.:***.*:.. *.: ** *.* ::* ::: **.*: ******:* :********:** **:*:*::**:* *: : ::**********:::* ** *::** *:: * **::. :: *******: ****:*** :. :*****:*:* ** .:: : :* * . : *:*::** :: :.**.*.: *.* ***** :**:::* :*:** .. * ** * ********** .**.*:. * * :. : : .: :* * * : :. :** :** :: :: *.* ::**::********** ** : :: * :* . :. ::***:****: ** **:*: .:.::**:* : ::*:*: :*.*: ** ::**:***::***********.**** :**.* ***:******::.* * :*.*:** .:* : *: . : . .: :. :. * *** :*: *. : : : : * : : *:: *: : *. : : * : .:* * ***** * :*: **.:** ", "identical_positions": 326, "similar_positions": 241, "identity": "34.83%" }, { "cls_id": "homologset.agr.FB:FBgn0004509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23188-1", "uniprot_id": "FURIN_MOUSE", "id": "P23188-1", "name": "Furin", "aln": "----------------------------------------------------------------------------------------------------------------MELRSWLLWVVAAAGAVVL-------------------------------------------------LAADAQGQK----------------------------------------IFTNTWAVHIPGG-PAVADRVAQKHGFHNLG-QIFGD--YYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEP-----------------TDPKFPQQWYLS--GVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAD-DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLG---EPNHITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLSTPPESS------GCKTLTSSQACVVCEEGYS----------------------------------LHQKSCVQHCPP------------------------------------------------------------------------GFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCLSCPSHASLDPVEQTCSRQSQSSR----------------------------ESRPQQQPPALRPEVEMEPRLQAG-LASHLPEVLAGLSCLIIVLIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23377-1", "uniprot_id": "FURIN_RAT", "id": "P23377-1", "name": "Furin", "aln": "----------------------------------------------------------------------------------------------------------------MELRPWLLWVVAAAGALVL-------------------------------------------------LAAEARGQK----------------------------------------IFTNTWAVHISGG-PAVADSVARKHGFHNLG-QIFGD--YYHFWHRAVTKRSLSPHRPRHSRLQRVPQVKWLEQQVAKQRAKRDVYQEP-----------------TDPKFPQQWYLS--GVTQRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN-DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIEILAEPKDIGKRLEVRKTVTACLG---EPNHISRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASEGLSAPPESS------GCKTLTSSQACVVCEEGFS----------------------------------LHQKSCVQRCPP------------------------------------------------------------------------GFTPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCLSCPSHASLDPVEQTCSRQSQSSR----------------------------ESRPQQPPPALRPEVEVEPRLRAG-LASHLPEVLAGLSCLIIALIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09958-1", "uniprot_id": "FURIN_HUMAN", "id": "P09958-1", "name": "Furin", "aln": "----------------------------------------------------------------------------------------------------------------MELRPWLLWVVAATGTLVL-------------------------------------------------LAADAQGQK----------------------------------------VFTNTWAVRIPGG-PAVANSVARKHGFLNLG-QIFGD--YYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP-----------------TDPKFPQQWYLS--GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN-DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLG---EPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESS------GCKTLTSSQACVVCEEGFS----------------------------------LHQKSCVQHCPP------------------------------------------------------------------------GFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR----------------------------ESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29121-1", "uniprot_id": "PCSK4_MOUSE", "id": "P29121-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "----------------------------------------------------------------------------------------------------------------MRPSQTELWLGLTLTLALL------------------------------------------------AVRWASAQAP----------------------------------------IYVSSWAVRVTKG-YQEAERLARKFGFVNLG-QIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKDPKVRWFEQQTLRRRVKR-SLVVP-----------------TDPWFSKQWYMN--KEIQQDLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAE-DWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCAIRVVHTPTPILPRMLVPKNVTACSDG-SRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYFNTGTLYYYTLLLYGTAEDMTARPQAPQVTSRARACVQRDTEGLCQESHSPLS----------------------------------ILAGLCLISSQQ------------------------------------------------------------------------WWWLYS--------HPQQPVTE-GQASCHP--------------PVTPAAAA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q78EH2-1", "uniprot_id": "PCSK4_RAT", "id": "Q78EH2-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "----------------------------------------------------------------------------------------------------------------MRPSQTALWLGLVLSLALL------------------------------------------------AVGWASARPP----------------------------------------IYVSSWAVRVTKG-YQEAERLARKFGFVNLG-QIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKEPKVRWFEQQTLRRRVKR-SLVVP-----------------TDPWFSKQWYMN--KEIEQDLNILKVWNQGLTGRGVVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAE-DWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCTIRVVHTPTPILPRMLVPKNVTVCCDG-SRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYYNTGTLYYCTLLLYGTAEDMTARPQTP------------------QESHCPLS----------------------------------IVAELCLISSKQ------------------------------------------------------------------------WWWLYS--------HTQQPVTK-GQDSCHP--------------PTTPARQLDQRLHCLFPAPHAGS----------------------------ASEPLQG-------LSP---------LAAILAISLG-PWCCPC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UW60-1", "uniprot_id": "PCSK4_HUMAN", "id": "Q6UW60-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "----------------------------------------------------------------------------------------------------------------MRPAPIALWLRLVLALALVRP---------------------------------------------RAVGWAPVRAP----------------------------------------IYVSSWAVQVSQG-NREVERLARKFGFVNLG-PIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKR-SVVVP-----------------TDPWFSKQWYMN--SEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQAE-DWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRPTPILPLIYIRENVSACAG---LHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRYTLLLYGTAEDMTARPTGPQVTSS--ACVQRDTEGLCQACDGPAY----------------------------------ILGQLCLAYCPP------------------------------------------------------------------------RFFNHTRLVTAGPGHTAAPALR-VCSSCHASCYTCRGGSPRDCTSCPPSSTLDQQQGSCMGPTTPDS----------------------------RPRLRAA-------ACPHHRCPASAMVLSLLAVTLGGPVLCGMSMDLPLYAWLSRARATPTK------------------PQVWLPAGT--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26016-1", "uniprot_id": "FUR11_DROME", "id": "P26016-1", "name": "Furin-like protease 1, isoforms 1/1-X/2", "aln": "MKNDVVRWSRQPTSNTTNSSSSSRSDSNSTHKHRSKSNKLNARQLGSNAARSCQQRSSVATTLEDEQQTIIECDIGNFNFDCNLFKTSFLTQHKQKRSGKSSSKSKSNRSRPLAKTKAVFLLALQFSAVVFLCNINVGFVAGSVATAASSAGGSSPAAPSSAPSSPPTVAVPPPPPPSSALKVDPNGQSPVLPPYVLDYETGGKAKLTPNNGKFGQSGSSGSNNNHIVGHYTHTWAVHIPNGDNGMADAVAKDHGFVNLG-KIFDD--HYHFAHHKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLN--RGGGLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDP-SWSRNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTVNHC-----RSVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEIHNEGRYMGHALLREWSLIFYGTTQSIGPNDPISVPKPSGSEATTPNSSSTTSNLHQAYSPQYPRIPPNNFGSSPSGGSKLPLGKVPPPNKSSYVTNNPLLNSAPPKQGYQQISATYGVILGKANGKSNNNSKEKTNNKGNKSNNGNKGKSGGSSGNRKEQTTQSTIIQTSTSKNKYYRISQQQQQKNNKQDRNGVQTQRPKANSGEKSYDEKSRKVVGEITTNSGNGSIKAAKQVKESTTTSSNSRIPKLFERYEKIQAIFPELEPYENSSPKGKPKQAKQGKQFEVDLFKPTNGGNSRQGNTKKSPSVPPPSQTMATLSILPILPAGGSSFLPDQKILKKQQLLMAAAGVMAPAQVEVEMEEVHATPDYEARKDQRKEVNGPNAQITQWDMIFYGTETPAQPDDVANPSQSNQFNLYGNDMAHNDVEYDSTGQWRNMQQVGEVGMTRDHSNTAACLKWSDRKCLGLSLLFFMIMQVFFLNFKHANDNNNKNKNNIIKCIR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13134-1", "uniprot_id": "KEX2_YEAST", "id": "P13134-1", "name": "Kexin", "aln": "-------------------------------------------------------------------------------------------------------------MKVRKYITLCFWWAFSTSALVSSQ----------------------------------------------QIPLKDHTSR----------------------------------------QYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSSLLP-------VKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLS---DDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSG--SGEYIHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENG-HRIDFHSWRLKLFGESIDSSKTETFVFGNDKEEVEPAATESTVSQYSASSTS----------------------------------ISISATSTSSIS-------------------------------------------------------------------------IGVETSAIPQTTTASTDPDSDPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRS-----------------------------RAETYEFDIIDTDSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKLQELQPDVPPSSGRS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : . .... .* . . :: :: :. : :. . :: .*. : : *:: *:.: * . :* *:* :::***:: :: *: *: . .*:*.*. * *: .: ********::* .*..*..*:.:.* :.*:*:*.* :* ** ** : .***.**** ***: ::**. *. .*: .*.::** . *:::::****** . *.** ******* ::::.: . . * *** *::.::.*:*** : ::*:. *: .* ****:******: :* *::* *****:*:: : :: . : .* ..:*:: ** :*:* :** :: :: * . * : : . . :**. . : : . ** : * ** . .* . * * * .*:::* **:. *.*. * * : :.. : * ::* : . : . . ", "identical_positions": 136, "similar_positions": 176, "identity": "10.62%" }, { "cls_id": "homologset.agr.FB:FBgn0004510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFC3-1", "uniprot_id": "A0ABK0LFC3_RAT", "id": "A0ABK0LFC3-1", "name": "GA-binding protein alpha chain", "aln": "--MTKREAEELIEIEIDG-----TEKPECTEESIVEQTYA-PAECVSQAIDINEPIGNLKKLLEPRLQCSLDAHEICLQD-IQLDPDRSLFDQGVKTDGTVQLSVQVISYQG---IEPKLNILEIVKTAETVEVVIDPDAHHAEAEAHLVEEAQVITLDGTKHITTISDETS-----EQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPR--GEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVPSATP--------TTIKVINSSAKAAKVQRSPRISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVALAAASLQTEKDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06546-1", "uniprot_id": "GABPA_HUMAN", "id": "Q06546-1", "name": "GA-binding protein alpha chain", "aln": "--MTKREAEELIEIEIDG-----TEKAECTEESIVEQTYA-PAECVSQAIDINEPIGNLKKLLEPRLQCSLDAHEICLQD-IQLDPERSLFDQGVKTDGTVQLSVQVISYQG---IEPKLNILEIVKPADTVEVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETS-----EQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPR--GEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATP--------TTIKVINSSAKAAKVQRAPRISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00422-1", "uniprot_id": "GABPA_MOUSE", "id": "Q00422-1", "name": "GA-binding protein alpha chain", "aln": "--MTKREAEELIEIEIDG-----TEKAECTEESIVEQTYT-PAECVSQAIDINEPIGNLKKLLEPRLQCSLDAHEICLQD-IQLDPDRSLFDQGVKTDGTVQLSVQVISYQG---MEPKLNILEIVKTAETVEVVIDPDAHHAEAEAHLVEEAQVITLDGTKHITTISDETS-----EQVTRWAAALEGYRKEQERLGIPYDPIHWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPR--GEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVPPATP--------TTIKVINSSAKAAKVQRSPRISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVIECEQKKLARMQLHGIAQPVTAVALAATSLQADKEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04688-1", "uniprot_id": "ELG_DROME", "id": "Q04688-1", "name": "DNA-binding protein Ets97D", "aln": "MNSSNDLSDELIRRLSVGGALEEVIASEMFEDSIDVETEAEPDDIIIVHMDIREPLSMLKSLVEQKIGVCLNYYTFWLQDAQELESHKNLVDQCVKGEGLVQINVQIQTIRKRINIADVLKPTEAALAALAEEVVGQLSPPETASQKSSSSESPIKTPLKRMHKEDSEEESVEGKDVKPVLNWVLDSK-FKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQELCAMTHEEFNQKLPRDPGNIFWTHLQLLKECNFVSVVHKRAEEQRKPKQPRIMSANSISTNSGGSLSLEQRIMRKSYQSVKSSDSVESTTSSMNPSNYTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGYDANELSTLVSEGK----------------TAPERVAATETITEDT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::***. * . .* *:** :* : * : : :**.**:. **.*:* :: .*: : : *** :*:..:.*.** ** :* **:.**: : : : *: * . .* : *** : .. .: :: .*: : * * .:*: : * .*. : :::** ** ** . .*: :* :*: *.:*:*.:..*::: ::.*:***::.:*:* *::** *:*:*:**:**:: :.* :: * : :*:.*. .:.. :: .*.*::. .:. * : . . :*****:********:*** : * *.*** ******.:*: **: **::****:*******************.**.****.*** **** ****.* **. ** * : ** .::: :: ", "identical_positions": 161, "similar_positions": 145, "identity": "33.47%" }, { "cls_id": "homologset.agr.FB:FBgn0004512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5X0E4-1", "uniprot_id": "ABCB5_MOUSE", "id": "B5X0E4-1", "name": "ATP-binding cassette sub-family B member 5", "aln": "MANSERTNGLQET--------NQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLING-------CLVQTNRTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAA-------RQTTRIRKQFFHSILA-QDISWFDGSD-ICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG----YTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFST---AGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGE----------KEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQ----GLYYSLAMAQDIKK--------VDEQMESRTCSTAGNAS--------------------YGSLCDVNSAKA------PCTDQLEEAVHHQKTS------LPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVT-MFE-DKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILIS--FIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINSCSQSGE-KPDTC---------EGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQV-------LLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSR-MVPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKLVAAH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AEL4-1", "uniprot_id": "D4AEL4_RAT", "id": "D4AEL4-1", "name": "ATP-binding cassette sub-family B member 5", "aln": "MAHSERANGLQES--------NQRYGSLQEQLPKAGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHFING-------CLVQTNKTKYQNCSQSQEKLNEDIIMLTLYYVGIGAAALVLGYVQISFWVITAA-------RQTTRIRKQFFHSILA-QDISWFDGTD-ICELNTRMNGDISKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLAILSTSPLIMAASALCSRMVISLTSKELDAYSKAGAVAEEALSSIRTVTAFGAQEKEIQRYTQNLKDAKDAGIKRAIASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG----YTVGTILAVFFSVIHSSYCIGSVAPHLETFTIARGAAFNIFHVIDKKPNIDNFST---AGYKPESIEGNIEFKNVSFSYPSRPSAKILKGFNLKIKSGETVALVGPSGSGKTTTVQLLQRLYDPEEGCITVDENDIRTQNVRHYREQIGVVSQEPVLFGTTIGNNIKFGREGVSE----------EEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQAALEKASKGRTTLVVAHRLSTIRGADLIVTMKDGEVVEKGIHAELMAKQ----GLYYSLAVAQDIKK--------VDEQMESRTCSAAGNAS--------------------NGSLCNVNSAKS------PCTDQFEEAVPHQKTT------LPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPAFSIIFGKLVT-MFE-DKNKTTLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEEILAMRLRHSAFKAMLYQDMAWYDEKDNSTGALTTTLAVDVAQIRGAATSRLGIITQDVTNMSLSILIS--FVYGWEMTLLILSFAPILAVTGMIQTAAMAGFANKDKQELKRAGKIATEAVENIRTVVSLTREKAFEHMYEETLRTQHRNALKRAHITGSCYAVSHAFVHFAHAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGAAHLFALLKNKPSIDSCSQNGE-KPDAC---------EGNLEFREVSFFYPCRPEVPVLQDMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQV-------LLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSR-MVPLEEIKEVADAANIHSFIEGLPGKYSTQVGLRGMHLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKMVQQALDKARRGRTCLVVAHRLSTIQNADMIVVLQNGRIKEQGTHQELLRNGETYFKLATAH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M3G0-4", "uniprot_id": "ABCB5_HUMAN", "id": "Q2M3G0-4", "name": "ATP-binding cassette sub-family B member 5", "aln": "MENSERAEEMQEN--------YQRNGTAEEQ-PKLRKEAVGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISG-------CLVQTNTTNYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYIQISLWIITAA-------RQTKRIRKQFFHSVLA-QDIGWFDSCD-IGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPG----YTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFST---AGYKPESIEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTD----------EEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKR----GLYYSLVMSQDIKK--------ADEQMESMTYSTERKTN--------------------SLPLHSVKSIKS------DFIDKAEESTQSKEIS------LPEVSLLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIIT-MFG-NNDKTTLKHDAEIYSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIIS--FIYGWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGK-KPDTC---------EGNLEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-------LFDGVDAKELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSR-VVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKLVNAQSVQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08183-1", "uniprot_id": "MDR1_HUMAN", "id": "P08183-1", "name": "ATP-dependent translocase ABCB1", "aln": "MDLEGDRNGGAKKK----NFFKLNNKSE--KDKKEKKPTVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMN--LEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAG-------RQIHKIRKQFFHAIMR-QEIGWFDVHD-VGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE------YSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSK---SGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTM----------DEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEK----GIYFKLVTMQTAGNEVELENAADESKSEIDALEMSSNDS--------------------RSSLIRKRSTRRSVRGSQAQDRKLSTK-EALDES------IPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIG-VFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIIS--FIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGL-MPNTL---------EGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKV-------LLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSR-VVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTKRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21447-1", "uniprot_id": "MDR1A_MOUSE", "id": "P21447-1", "name": "ATP-dependent translocase ABCB1", "aln": "MELEEDLKGRADK-----NFSKMGKKSK--KEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVS---KNSTNMSEADKRAMFAK--LEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAG-------RQIHKIRQKFFHAIMN-QEIGWFDVHD-VGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE------YSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSK---SGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTM----------DEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREK----GIYFKLVMTQTAGNEIELGNEACKSKDEIDNLDMSSKDS--------------------GSSLIRRRSTRKSICGPHDQDRKLSTK-EALDED------VPPASFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVG-VFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIIS--LIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGL-KPNML---------EGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------FLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSR-VVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQAGAKRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06795-1", "uniprot_id": "MDR1B_MOUSE", "id": "P06795-1", "name": "ATP-dependent translocase ABCB1", "aln": "MEFEENLKGRADK-----NFSKMGKKSK--KEKKEKKPAVGVFGMFRYADWLDKLCMILGTLAAIIHGTLLPLLMLVFGNMTDSFTKA-EASILP-SITNQSGPNSTLIISNSSLEEEMAIYAYYYTGIGAGVLIVAYIQVSLWCLAAG-------RQIHKIRQKFFHAIMN-QEIGWFDVHD-VGELNTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKNVGIKKAITASISIGIAYLLVYASYALAFWYGTSLVLSNE------YSIGEVLTVFFSILLGTFSIGHLAPNIEAFANARGAAFEIFKIIDNEPSIDSFST---KGYKPDSIMGNLEFKNVHFNYPSRSEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTM----------DEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREK----GIYFKLVMTQTRGNEIEPGNNAYGSQSDTDASELTSEES--------------------KSPLIR-RSIYRSVHRKQDQERRLSMK-EAVDED------VPLVSFWRILNLNLSEWPYLLVGVLCAVINGCIQPVFAIVFSRIVG-VFSRDDDHETKRQNCNLFSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQNVANLGTGVILS--LVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAQQLMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIRIIEKTPEIDSYSTEGL-KPTLL---------EGNVKFNGVQFNYPTRPNIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------FLDGKEIKQLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSR-AVSHEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMV--QAGAKRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43245-1", "uniprot_id": "MDR1_RAT", "id": "P43245-1", "name": "ATP-dependent translocase ABCB1", "aln": "MEFEEGLNGRADK-----NFSKMGKKSK--KEK-EKKPAVGIFGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTPS-RDPHSDRAITNQSEINSTHTVSDTSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAG-------RQIHKIRQKFFHAIMN-QEIGWFDVND-AGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNE------YSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFST---KGHKPDSIMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTM----------DEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEK----GIYFKLVMTQTRGNEIEPGNNAYESQSDTGASELTSEES--------------------KSPLIR-RSIRRSIHRRQDQERRLSSK-EDVDED------VPMVSFWQILKLNISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVG-VFSRDDDHETKQRNCNLFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIGIIEKIPEIDSYSTEGL-KPNWL---------EGNVKFNGVKFNYPTRPNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTV-------FLDGKEIKQLNVQCVRA-LGIVSQEPILFDCSIAENIAYGDNSR-VVSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMV--QAGAKRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21440-1", "uniprot_id": "MDR3_MOUSE", "id": "P21440-1", "name": "Phosphatidylcholine translocator ABCB4", "aln": "MDLEAARNGTARR---LDGDFELGSISNQGREKKKKVNLIGLLTLFRYSDWQDKLFMFLGTLMAIAHGSGLPLMMIVFGEMTDKFVDN------TGNFSLPVNFSLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAG-------RQIKKIRQKFFHAILR-QEMGWFDIKG-TTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE------YTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSE---RGHKPDNIKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTM----------DEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKE----GIYFRLVNMQTAGSQILSEEFEVELSDEKAAGDVAPNGW--------------------KARIFR-NSTKKSLKSP--HQNRLDEETNELDAN------VPPVSFLKVLKLNKTEWPYFVVGTVCAIANGALQPAFSIILSEMIA-IFGPGDD-AVKQQKCNMFSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIIS--FIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGHASSFAPDYAKAKLSAAYLFSLFERQPLIDSYSGEGL-WPDKF---------EGSVTFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------LLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSR-VVPHDEIVRAAKEANIHPFIETLPQKYNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMVNIQAGTQNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21439-1", "uniprot_id": "MDR3_HUMAN", "id": "P21439-1", "name": "Phosphatidylcholine translocator ABCB4", "aln": "MDLEAAKNGTAWRPTSAEGDFELGISSKQKRKKTKTVKMIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDT------AGNFSFPVNFSLSLLNPGKILEEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAG-------RQIRKIRQKFFHAILR-QEIGWFDIND-TTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE------YTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSE---RGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTM----------DEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKE----GVYFKLVNMQTSGSQIQSEEFELN--DEKAATRMAPNGW--------------------KSRLFR-HSTQKNLKNSQMCQKSLDVETDGLEAN------VPPVSFLKVLKLNKTEWPYFVVGTVCAIANGGLQPAFSVIFSEIIA-IFGPGDD-AVKQQKCNIFSLIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIIS--FIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDSYSEEGL-KPDKF---------EGNITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSR-VVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTQNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00449-1", "uniprot_id": "MDR49_DROME", "id": "Q00449-1", "name": "Multidrug resistance protein homolog 49", "aln": "MVKKEESRLPQAG-----------DFQLKEGSVVDATRKYSYFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYGEFTSLLVDRTVGVGTSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLR-QDIAWYDTSS-GSNFASKMTEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDPMDE---KGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQ----------ADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERR----GLYCELVSITQRKEATEADEGAVAGRPLQKSQNLSDEETDD---------DEEDEEEDEEPELQTSGSSRDSGFRASTRRKRRSQRRKKKKDKEV----VSKVSFTQLMKLNSPEWRFIVVGGIASVMHGATFPLWGLFFGDFFG-ILSDGDD-DVVRAEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVG--FVFSWQQTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGLVFALGQAAPFLAYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDLFKRTSTQPNPPQSPYNTVEKS---------EGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVN-------LSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELMALNKIYANLYLMQQVSG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12866-1", "uniprot_id": "STE6_YEAST", "id": "P12866-1", "name": "Alpha-factor-transporting ATPase", "aln": "-------------------------------MNFLSFKTTKHYHIFRYVNIRNDYRLLMIMIIGTVATGLVPAITSILTGRVFDLLSV-----------------FVANGSHQGLYSQLVQRSMAVMALGAASVPVMWLSLTSWMHIGE-------RQGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNLVAICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKAAQLLTWSMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGFWFGSAMIKKGK------LNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQIESDDYLYLMKEGEVVESGTQSELLADPTTTFSTWYHLQNDYSDAKTIVDTETEEKSIHTVESFNSQLETPKLGSCLSNLGYDETDQLSFYEAIYQKRSNVRTRRVKVEEENIGYALKQQKNTESSTGPQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPVFSYTFSFLLEGIVPSTDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNEVMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWA--LVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTIKCLQAEFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVMIHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTKLYNCEVGKIK-------IDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRDNLTYG--LQDEILEIEMYDALKYVGIHDFVISSPQGLDTRID--TTLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSSIINEIVKKGPPALLTMVITHSEQMMRSCNSIAVLKDGKVVERGNFDTLYNNRGELFQIVSNQSS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**: : : : : . :* : : : .: .:* . : . .* :**. ::.: : : : *:* :::. :.:: .. .: : . : : : .: .*.*:* :. *.: : ::: :.** :.*. : : . : * : *. * ::: : : .: * . . :: .:*:* ::: . . : :.: : :. . .: . * :: ::. .. : . : . : * .: * **:* . :**...: . .*: . :** .*.**:* :*: *:** * : :: .::: : . * ** *. .** *: :** * . :: * : * ** :*. :* :* *. :****:**:*****::*:. :*:****.**** . : *: :* **::::*.** : . * : :. * :.*.* : **: . : * . : . :. .: : : . .::* ..: * * :. :. .. :. *:..: :. . : : . . :* .: : ::: ::. *... : : : * .::. :. : . : .:: . :: .*: ::: : *.: : : : * : : : : *::*: * * . * : ::. * :. : . :* *: . :: . : *: . .*. : ::.. . . : : : * ** : :.:.: : . *: ::* ** **** * ** : *: * : :.* . : :* .:* *:*:**: :* :*::** : : *: . .** *: * .* :. ***** **:.*****:::.::*:***.***** *..:::. :.:. . :.::* ::..: * *:. * : *:*..: * .: : ", "identical_positions": 177, "similar_positions": 376, "identity": "12.94%" }, { "cls_id": "homologset.agr.FB:FBgn0004513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5X0E4-1", "uniprot_id": "ABCB5_MOUSE", "id": "B5X0E4-1", "name": "ATP-binding cassette sub-family B member 5", "aln": "MANSERTNGLQET--------NQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLING-------CLVQTN-------RTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILA-QDISWFDGSD-ICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG----YTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFST--AGFVPEC-IEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGE----------KEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQ----GLYYSLAMAQDIKK--------VDEQMESRTCSTAGNASY--------------------GSLCDVNSAKA------PCTDQLEEAVHHQKTSLPEVS------LLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVT-MFE-DKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILIS--FIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINS-----CSQSGEKPDTCEGN-----LEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQV-------LLDGVDVK-ELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKLVAAH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AEL4-1", "uniprot_id": "D4AEL4_RAT", "id": "D4AEL4-1", "name": "ATP-binding cassette sub-family B member 5", "aln": "MAHSERANGLQES--------NQRYGSLQEQLPKAGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHFING-------CLVQTN-------KTKYQNCSQSQEKLNEDIIMLTLYYVGIGAAALVLGYVQISFWVITAARQTTRIRKQFFHSILA-QDISWFDGTD-ICELNTRMNGDISKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLAILSTSPLIMAASALCSRMVISLTSKELDAYSKAGAVAEEALSSIRTVTAFGAQEKEIQRYTQNLKDAKDAGIKRAIASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG----YTVGTILAVFFSVIHSSYCIGSVAPHLETFTIARGAAFNIFHVIDKKPNIDNFST--AGYKPES-IEGNIEFKNVSFSYPSRPSAKILKGFNLKIKSGETVALVGPSGSGKTTTVQLLQRLYDPEEGCITVDENDIRTQNVRHYREQIGVVSQEPVLFGTTIGNNIKFGREGVSE----------EEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQAALEKASKGRTTLVVAHRLSTIRGADLIVTMKDGEVVEKGIHAELMAKQ----GLYYSLAVAQDIKK--------VDEQMESRTCSAAGNASN--------------------GSLCNVNSAKS------PCTDQFEEAVPHQKTTLPEVS------LLKIFKLSKSEWPFVVLGTLASALNGSVHPAFSIIFGKLVT-MFE-DKNKTTLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEEILAMRLRHSAFKAMLYQDMAWYDEKDNSTGALTTTLAVDVAQIRGAATSRLGIITQDVTNMSLSILIS--FVYGWEMTLLILSFAPILAVTGMIQTAAMAGFANKDKQELKRAGKIATEAVENIRTVVSLTREKAFEHMYEETLRTQHRNALKRAHITGSCYAVSHAFVHFAHAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGAAHLFALLKNKPSIDS-----CSQNGEKPDACEGN-----LEFREVSFFYPCRPEVPVLQDMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQV-------LLDGVDVK-ELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPGKYSTQVGLRGMHLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKMVQQALDKARRGRTCLVVAHRLSTIQNADMIVVLQNGRIKEQGTHQELLRNGETYFKLATAH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M3G0-4", "uniprot_id": "ABCB5_HUMAN", "id": "Q2M3G0-4", "name": "ATP-binding cassette sub-family B member 5", "aln": "MENSERAEEMQEN--------YQRNGTAEEQ-PKLRKEAVGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISG-------CLVQTN-------TTNYQNCTQSQEKLNEDMTLLTLYYVGIGVAALIFGYIQISLWIITAARQTKRIRKQFFHSVLA-QDIGWFDSCD-IGELNTRMTDDIDKISDGIGDKIALLFQNMSTFSIGLAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSSIRTVIAFRAQEKELQRYTQNLKDAKDFGIKRTIASKVSLGAVYFFMNGTYGLAFWYGTSLILNGEPG----YTIGTVLAVFFSVIHSSYCIGAAVPHFETFAIARGAAFHIFQVIDKKPSIDNFST--AGYKPES-IEGTVEFKNVSFNYPSRPSIKILKGLNLRIKSGETVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTD----------EEMERAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKR----GLYYSLVMSQDIKK--------ADEQMESMTYSTERKTNS--------------------LPLHSVKSIKS------DFIDKAEESTQSKEISLPEVS------LLKILKLNKPEWPFVVLGTLASVLNGTVHPVFSIIFAKIIT-MFG-NNDKTTLKHDAEIYSMIFVILGVICFVSYFMQGLFYGRAGEILTMRLRHLAFKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIIS--FIYGWEMTFLILSIAPVLAVTGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRNTSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGETLVLAPEYSKAKSGAAHLFALLEKKPNIDS-----RSQEGKKPDTCEGN-----LEFREVSFFYPCRPDVFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-------LFDGVDAK-ELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKLVNAQSVQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08183-1", "uniprot_id": "MDR1_HUMAN", "id": "P08183-1", "name": "ATP-dependent translocase ABCB1", "aln": "MDLEGDRNGGAKKK----NFFKLNNKSE--KDKKEKKPTVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNR-------SDINDTGFFMN--LEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMR-QEIGWFDVHD-VGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGE------YSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSK--SGHKPDN-IKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTM----------DEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEK----GIYFKLVTMQTAGNEVELENAADESKSEIDALEMSSNDSR--------------------SSLIRKRSTRRSVRGSQAQDRKLSTK-EALDESIPPVS------FWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIG-VFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIIS--FIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDS-----YSTEGLMPNTLEGN-----VTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKV-------LLDGKEIK-RLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTKRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21447-1", "uniprot_id": "MDR1A_MOUSE", "id": "P21447-1", "name": "ATP-dependent translocase ABCB1", "aln": "MELEEDLKGRADK-----NFSKMGKKSK--KEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVS---KNSTNM-------SEADKRAMFAK--LEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMN-QEIGWFDVHD-VGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKE------YSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSK--SGHKPDN-IQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTM----------DEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREK----GIYFKLVMTQTAGNEIELGNEACKSKDEIDNLDMSSKDSG--------------------SSLIRRRSTRKSICGPHDQDRKLSTK-EALDEDVPPAS------FWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVG-VFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIIS--LIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDS-----YSTQGLKPNMLEGN-----VQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------FLDGKEIK-QLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQAGAKRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06795-1", "uniprot_id": "MDR1B_MOUSE", "id": "P06795-1", "name": "ATP-dependent translocase ABCB1", "aln": "MEFEENLKGRADK-----NFSKMGKKSK--KEKKEKKPAVGVFGMFRYADWLDKLCMILGTLAAIIHGTLLPLLMLVFGNMTDSFTKA-EASILP-SITNQ-------SGPNSTLIISNSSLEEEMAIYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMN-QEIGWFDVHD-VGELNTRLTDDVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQQKELERYNKNLEEAKNVGIKKAITASISIGIAYLLVYASYALAFWYGTSLVLSNE------YSIGEVLTVFFSILLGTFSIGHLAPNIEAFANARGAAFEIFKIIDNEPSIDSFST--KGYKPDS-IMGNLEFKNVHFNYPSRSEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLEGVVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTM----------DEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREK----GIYFKLVMTQTRGNEIEPGNNAYGSQSDTDASELTSEESK--------------------SPLIR-RSIYRSVHRKQDQERRLSMK-EAVDEDVPLVS------FWRILNLNLSEWPYLLVGVLCAVINGCIQPVFAIVFSRIVG-VFSRDDDHETKRQNCNLFSLFFLVMGLISFVTYFFQGFTFGKAGEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQNVANLGTGVILS--LVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKQLEISGKIATEAIENFRTIVSLTREQKFETMYAQSLQVPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVAQQLMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIRIIEKTPEIDS-----YSTEGLKPTLLEGN-----VKFNGVQFNYPTRPNIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------FLDGKEIK-QLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRAVSHEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMV--QAGAKRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43245-1", "uniprot_id": "MDR1_RAT", "id": "P43245-1", "name": "ATP-dependent translocase ABCB1", "aln": "MEFEEGLNGRADK-----NFSKMGKKSK--KEK-EKKPAVGIFGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVFGYMTDSFTPS-RDPHSDRAITNQ-------SEINSTHTVSDTSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMN-QEIGWFDVND-AGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNE------YSIGQVLTVFFSILLGTFSIGHLAPNIEAFANARGAAYEIFKIIDNEPSIDSFST--KGHKPDS-IMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGRENVTM----------DEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEK----GIYFKLVMTQTRGNEIEPGNNAYESQSDTGASELTSEESK--------------------SPLIR-RSIRRSIHRRQDQERRLSSK-EDVDEDVPMVS------FWQILKLNISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVG-VFSRDDDHETKQRNCNLFSLLFLVMGMISFVTYFFQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSRLAVVTQNVANLGTGIILSLVLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVFGAMAAGNTSSFAPDYAKAKVSASHIIGIIEKIPEIDS-----YSTEGLKPNWLEGN-----VKFNGVKFNYPTRPNIPVLQGLSFEVKKGQTLRLVGSSGCGKSTVVQLLERFYNPMAGTV-------FLDGKEIK-QLNVQCVRA-LGIVSQEPILFDCSIAENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCVVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMV--QAGAKRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21440-1", "uniprot_id": "MDR3_MOUSE", "id": "P21440-1", "name": "Phosphatidylcholine translocator ABCB4", "aln": "MDLEAARNGTARR---LDGDFELGSISNQGREKKKKVNLIGLLTLFRYSDWQDKLFMFLGTLMAIAHGSGLPLMMIVFGEMTDKFVDN------TGNFSLP-------VNFSLSMLNPGRILEEEMTRYAYYYSGLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILR-QEMGWFDIKG-TTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE------YTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSE--RGHKPDN-IKGNLEFSDVHFSYPSRANIKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQEPVLFSTTIAENIRYGRGNVTM----------DEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKE----GIYFRLVNMQTAGSQILSEEFEVELSDEKAAGDVAPNGWK--------------------ARIFR-NSTKKSLKSP--HQNRLDEETNELDANVPPVS------FLKVLKLNKTEWPYFVVGTVCAIANGALQPAFSIILSEMIA-IFGPGDD-AVKQQKCNMFSLVFLGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNTANLGTGIIIS--FIYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEMEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLHGPYRNSVRKAHIYGITFSISQAFMYFSYAGCFRFGSYLIVNGHMRFKDVILVFSAIVLGAVALGHASSFAPDYAKAKLSAAYLFSLFERQPLIDS-----YSGEGLWPDKFEGS-----VTFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSV-------LLDGQEAK-KLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVPHDEIVRAAKEANIHPFIETLPQKYNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYFSMVNIQAGTQNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21439-1", "uniprot_id": "MDR3_HUMAN", "id": "P21439-1", "name": "Phosphatidylcholine translocator ABCB4", "aln": "MDLEAAKNGTAWRPTSAEGDFELGISSKQKRKKTKTVKMIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDT------AGNFSFP-------VNFSLSLLNPGKILEEEMTRYAYYYSGLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILR-QEIGWFDIND-TTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKE------YTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARGAAYVIFDIIDNNPKIDSFSE--RGHKPDS-IKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTM----------DEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKE----GVYFKLVNMQTSGSQIQSEEFELN--DEKAATRMAPNGWK--------------------SRLFR-HSTQKNLKNSQMCQKSLDVETDGLEANVPPVS------FLKVLKLNKTEWPYFVVGTVCAIANGGLQPAFSVIFSEIIA-IFGPGDD-AVKQQKCNIFSLIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIIS--FIYGWQLTLLLLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYVEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDS-----YSEEGLKPDKFEGN-----ITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAK-KLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTQNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00748-1", "uniprot_id": "MDR65_DROME", "id": "Q00748-1", "name": "Multidrug resistance protein homolog 65", "aln": "MERDEVSTSSSEG---------KSQEEAPMAEGLEPTEPIAFLKLFRFSTYGEIGWLFFGFIMCCIKALTLPAVVIIYSEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREENNEALYDDSISYGILLTIASVVMFISGIFSVDVFNMVALRQVTRMRIKLFSSVIR-QDIGWHDLAS-KQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSYGWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQRYENFLVPARKASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYTPAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLST--DGKLLNYGLRGDVEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYGKPGATQ----------KEIEAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALE----GAYYNMVRAGDINMPDEVEKEDSIEDTKQKSLALFEKSFET-------------------SPLNFEKGQKNSVQFEEPIIKALIKDTNAQSAEAPPEKPNFFRTFSRILQLAKQEWCYLILGTISAVAVGFLYPAFAVIFGEFYA-ALAEKDPEDALRR-TAVLSWACLGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVA--MYYNWKLALLCLANCPIIVGSVILEAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRVEVLIRQKLRWRGVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIKVSETLLYGSMMLAQSLAFTPAFSAALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEG------VRYRGIQFRYPTRPDAKILNGLDLEVLKGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTI-------HIDHDDIQHDLTLDGVRTKLGIVSQEPTLFERSIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACSGRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLISQGGIYAKLHKTQKDH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12866-1", "uniprot_id": "STE6_YEAST", "id": "P12866-1", "name": "Alpha-factor-transporting ATPase", "aln": "-------------------------------MNFLSFKTTKHYHIFRYVNIRNDYRLLMIMIIGTVATGLVPAITSILTGRVFDLLSV------------------------FVANGSHQGLYSQLVQRSMAVMALGAASVPVMWLSLTSWMHIGERQGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNLVAICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKAAQLLTWSMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGFWFGSAMIKKGK------LNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLRKNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQIESDDYLYLMKEGEVVESGTQSELLADPTTTFSTWYHLQNDYSDAKTIVDTETEEKSIHTVESFNSQLETPKLGSCLSNLGYDETDQLSFYEAIYQKRSNVRTRRVKVEEENIGYALKQQKNTESSTGPQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPVFSYTFSFLLEGIVPSTDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNEVMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWA--LVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTIKCLQAEFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVMIHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTKLYNCEVGKIK-------IDGTDVN-DWNLTSLRKEISVVEQKPLLFNGTIRDNLTYG-LQDEILEIEMYDALKYVGIHDFVISSPQGLDTRIDT--TLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSSIINEIVKKGPPALLTMVITHSEQMMRSCNSIAVLKDGKVVERGNFDTLYNNRGELFQIVSNQSS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**: : : . : :* : : : * .: . . ..: : . ** ::* ::: : : : : *.* : :.:: .. .: . : : . .: .*.*:* . *:: ::. : :* : *. : : : : * : :. * ::: : : .. . . : .**:* :: . . : *.. : : : : . . :: ::. .. : . . : * :: * **** . : :...:.. :*: . :** .*.**:* :*: *:** * : :: :*: : . . * ** *. .** *: :** * . . :: * * ** :*. :::* * :****:**:*****::::. **:****.**** . : *: :*:**::::*.** :.. * : :. * : *.* : :*: . :: : : . . . : : : .::* ..: * *.*: :. . . : * : :. . : : . . . :* .:. : ::: *:. .*... ::: : : .::. :. : . : .: : : .*::::: : *.: : : * : . : : *::*: * * . * : :: * : : * :* *: . :: . : : * : . .. : ::.. . . .* : : * ** . : ..:.:.: *:*: ::* ** **** * ** : *: * : :* : : .: :* .:* *:* **: :* :*::** : *: . .. * *: * .* :. ***** **:.*****:::.::*:***.***** *..:::. :... . :*::* . ::..: * *:.:* : *:*.. * : .: : ", "identical_positions": 175, "similar_positions": 364, "identity": "12.79%" }, { "cls_id": "homologset.agr.FB:FBgn0004516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18088-1", "uniprot_id": "DCE1_RAT", "id": "P18088-1", "name": "Glutamate decarboxylase 1", "aln": "MASSTPSP-ATSSNAGADPNTTNLR-PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFRERQASKNLLSCENSDPGARFRRTETDFSNLFAQDLLPAKNGE-EQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIIGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVP-KLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILDAKQKGFVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRH-KLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNR-EEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48318-1", "uniprot_id": "DCE1_MOUSE", "id": "P48318-1", "name": "Glutamate decarboxylase 1", "aln": "MASSTPSP-ATSSNAGADPNTTNLR-PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFRERQSSKNLLSCENSDQGARFRRTETDFSNLFAQDLLPAKNGE-EQTAQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVP-KLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILDAKQKGYVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRH-KLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELADYLYAKIKNR-EEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99259-1", "uniprot_id": "DCE1_HUMAN", "id": "Q99259-1", "name": "Glutamate decarboxylase 1", "aln": "MASSTPSSSATSSNAGADPNTTNLR-PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGE-EQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVP-KLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRH-KLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNR-EEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RDR2-1", "uniprot_id": "A0A8M1RDR2_DANRE", "id": "A0A8M1RDR2-1", "name": "Glutamate decarboxylase 1", "aln": "MAASAPSS--SSSGGVPDPNSTNLQPPSSNYDWSGVAHGCTRKLGMKICGFLQKNNNVDDKGRIVGLFNDQQ-PRSILTRDN-ERDSRFRRTETDFSNLYARDLLPAKNGE-EYTMQFLLEVVEILTNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELCDQPESLEQILVDCRDTLKYGVRTGHPRFFNQLSSGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQLTLKKMREIVGWPNGEGDGIFSPGGAISNMYSVMVARYKHYPEIKIKGMAAAP-RLVLFTSEHSHYSIKKASAVLGFGTENLILLRTDERGRVIPADLEAKVIDAKQKGFVPMFVNATAGSTVYGAFDPINEIADICEKYNMWLHVDGAWGGGLLMSRKHKH-KLSGIERANSVTWNPHKMMGVPLQCSAILVREKGLLQGCNSMCAGYLFQPDKQYDVTYDTGDKAIQCGRHVDIFKFWLMWKSKGTTGFEKHIDRCLELSEYLYHKIKNR-EGYEMVFQGEPQHTNVCFWYIPPSLRLLPDGEEKRHRLHKVAPKIKALMMECGTTMVGYQPQGEKVNFFRMVVSNPAVTRSDIDFLIDEIERLGQDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05683-1", "uniprot_id": "DCE2_RAT", "id": "Q05683-1", "name": "Glutamate decarboxylase 2", "aln": "MAS--PGS--GFWSFGSEDGSGDPENPGTARAWCQVAQKFTGGIGNKLCALLYGDS---EKPAESGGSVTSRAATRKVACTCDQKPCSCPKGDVNYALLHATDLLPACEGE-RPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQ---EYNWELADQPQNLEEILTHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVP-RLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEVKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKW-KLNGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYNIIKNR-EGYEMVFDGKPQHTNVCFWFVPPSLRVLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48320-1", "uniprot_id": "DCE2_MOUSE", "id": "P48320-1", "name": "Glutamate decarboxylase 2", "aln": "MAS--PGS--GFWSFGSEDGSADPENPGTARAWCQVAQKFTGGIGNKLCALLYGDS---GKPAEGGGSVTSRAATGKVACTCDQKPCNCPKGDVNYAFLHATDLLPACDGE-RPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQ---EYNWELADQPQNLEEILTHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVP-RLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEVKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKW-KLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYTIIKNR-EGYEMVFDGKPQHTNVCFWFVPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05329-1", "uniprot_id": "DCE2_HUMAN", "id": "Q05329-1", "name": "Glutamate decarboxylase 2", "aln": "MAS--PGS--GFWSFGSEDGSGDSENPGTARAWCQVAQKFTGGIGNKLCALLYGDA---EKPAESGGSQPPRAAARKAACACDQKPCSCSKVDVNYAFLHATDLLPACDGE-RPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQ---EYNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAALP-RLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKW-KLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNR-EGYEMVFDGKPQHTNVCFWYIPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20228-1", "uniprot_id": "DCE_DROME", "id": "P20228-1", "name": "Glutamate decarboxylase", "aln": "--------------MSLNPN------------------------GYKLSERTG--------------------------------------------KLTAYDLMPTTVTAGPETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKR---LLDLDVPDRALPLQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTKMREIIGWSG--GDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHFKEDGLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLIL--EPECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQKGTLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *:. * * **:*: * ** .*:::* ::* : **. **:***:*.:: . : :: *:. *:::: .* **** ::****::*****.***::.:*.:***:***************:*:* :.*.*****:**.. **.*::***:***:*:.: **.* :*: * :* .. * *: ***::.*:*:*. .*. *:**: *:: :*:*::*.:::* ::: * ** :*: *.****:** **** : :****:**: *:*:*.************: ::.*:***:********:**. ****:: .:*.*:: .**.* * *** **:**::******.:***** *:**:** *::*** *** : :: :** :* *::: : :.::: :*: .**.**::* ** : .. :: .* ::.* **. **: ** **.*** . : **** ::*..*... *:**:::**.***:**", "identical_positions": 233, "similar_positions": 172, "identity": "38.9%" }, { "cls_id": "homologset.agr.FB:FBgn0004556", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P9R1-1", "uniprot_id": "DDX51_MOUSE", "id": "Q6P9R1-1", "name": "ATP-dependent RNA helicase DDX51", "aln": "----------------------------------------------------MALFHIARYAGP---EAAGQGDTDAEAGSRARVLLERLQNRARERQQREPELETTGTAGEGEAAAAGKRRRRPRRRR-RVSGSATPNSEAPRAKRRKADKD-------------VDAGRGEEAPEELSAG--AEDPGANPQ-------------EDVQRPPAPGRVLGDFARRKTPKVQPFLPAWLAKPSCVK------KSVTEDLTPIEDIPEVHPDLQKQLRANGITSYFPVQAAVIPALLESADHGFLIGRGGYQP--SDLCVSAPTGSGKTLAFVIPVVQALLHRVVCHIRALVVLPTKELAQQVSKVFNIYTDTTPLRVALVTGQKSLAKEQESLVQKTADGFRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFYSEGPTGSCALLQRTQPQALTAASTCVPQMPLQKLLFSATLTQDPEKLQRLGLYQPRLFSTRLGQQSPKDTAEVDENS----------GKYTFPVGLTHHYVPCRLSSKPLIVLHLVLRMSCS----RALCFTNSRENSHRLYLLAQAFGG---VSVAEFSSRYGPGQRKKILKQFEQG----KIQLLISTDATARGIDVQGVELVINYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERKFLQMVSEAGVPELTHHEIPRKLLQPLVARYETALSQLEKTVKEEQKLKAA------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4S4-1", "uniprot_id": "A0A0G2K4S4_RAT", "id": "A0A0G2K4S4-1", "name": "ATP-dependent RNA helicase", "aln": "MPVAAPCCRQLLPGTDVCAKCSRTRDVTSASRSQGWLTSSKSVEEEPRRAAAMALFHIARYAGP---EAAGLGDTEAEAGGRARVLLERLQNRAREREQRQPELESTGTA----AEAPVRRRRRPRRRR-GVSGSVAEKPEAPRAKRQKVEDD-------------VDAGRGEETPEELSES--AEDPGESPQ-------------EDVQRPPAPGRVLGDFARKKVPKVQPFLPAWLAKPSCVK------KSVTEDLTPIEDIPEVHPDLQKQLRANGISSYFPVQAAVIPALLESADNGFLVGRGGYQP--SDLCVSAPTGSGKTLAFVIPVVQALLHRVVCHIRALVVLPTKELAQQVSKVFNIYTDTTPLRVALVTGQKSLAKEQESLVQKTADGFCCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFYTEDPTGSCALLQRTQPQAVTAASTCIPQMPLQKLLFSATLTQNPEKLQRLGLYQPRLFSTRLGHQSPRDTVEVDENL----------GKYTFPVGLTHHYVPCRLSSKPLIVFHLVLGMNFS----RALCFTNSRENSHRLFLLAQAFGG---VSVAEFSSRYGPGQRKKILKQFEQG----KIQLLISTDATARGIDVQGVELVINYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERKFLQMVSEAGVPELACHEVPRKLLQPLVARYETALSQLEKTVKEEQKLKAA------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8A6-1", "uniprot_id": "DDX51_HUMAN", "id": "Q8N8A6-1", "name": "ATP-dependent RNA helicase DDX51", "aln": "----------------------------------------------------MALFYVARYPGPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAS---TEPATRRRRRPRRRR-RVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAPGEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPRWLAEPNCVR------RNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRP--SDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDT-DGDGDS----------GKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFS----RVLCFTNSRENSHRLFLLVQAFGG---VDVAEFSSRYGPGQRRMILKQFEQG----KIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEERKQRAA------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRI7-1", "uniprot_id": "DDX51_DANRE", "id": "Q6DRI7-1", "name": "ATP-dependent RNA helicase DDX51", "aln": "----------------------------------------------------MALFTINRYLGE-------EEEEDSEKQSRSKALLAKLQKQVKARGQQSVSNTPKEEEEQQDDKEHKKRKHKLQETKGKIKKSESVQNTDPTEEADSSVKKKKKRKKSLSTEDVIVKIEENESENEKSVDITGPTPSSPVQFKAEK------AEELTSSSQSNYQVLGGFKEKDVQKVKRVLPQWLSQPDVIQ------KDIKSNLIPISEVPGICPTLLRKLQTNGIQSFFPVQAEVIPAILESVGSGLLVGPGGYRP--RDVCVSAPTGSGKTLAFVIPVVQALSKRVVRQVRALAVLPTKELAQQVSNVFSAYTEGSSLKVVMITGQKSFAAEQTALSEIRGGVSHSMADIVVATPGRLVDHINKNSSFSLQHLRFLIIDEADRMIDSMHQSWLSQVTKAVYSTPGET-HTSVFRRTVPGPITAASLSPPQIPLQKLLFSATLTQNPEKLQLLDLHQPRLFSS---THSLTDNPAQSQD------------TFHFPQGLSEYYVPCTFSKKPLIILHFLLRLKFS----PALCFTNSREGAHRLYLLVKLFGG---VEVAEFSSKLSPGERQKTLKDFEKG----KIPLLISTDAAARGIDINGVKCVINYDAPQYIRTYIHRVGRTARAGKAGLAFTFLLKVQEKRFLKMVSDAGSPGIQKQHVHPEALKSMESRYEQVLAELGTIVKEENEKKRF------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26802-1", "uniprot_id": "DDX51_DROME", "id": "P26802-1", "name": "Probable ATP-dependent RNA helicase Dbp73D", "aln": "----------------------------------------------------MELFTVNRYTEDLK-----EQKDGAQGTNNEDEILQKLLKKAAKRKRKHEAIEVVETP---------------------ILEKETSDVKESESKEEQVEEP--------------------------------EKPLEVVQ-------------EEDVPSNEFQVLGGDDSAAKKKKVQMQLPNWLAHPTIIEGGSLQPEEEVPASEAIDQLDYLEKYTCQALKQMKIKRLFPVQKQVIPWILEAHAK-----PPPFRP--RDICVSAPTGSGKTLAFAIPIVQLLSQRVDCKVRALVVLPVAELALQVYRVISELCSKTELEVCLLSKQHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRIMDAVFQNWLYHLDSHVKET-----TDQLLAGTQAPLCYAELQASFGKQPHKLLFSATLSQDPEKLQDLRLFQPRLFATVLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFALVEKYKWK----RFLCFTNSSDQATRLTFVLKVLFQKYSTKVSELSGNLSAKVRNERLRDFAAG----KINGLICSDALARGIDVADVDVVLSYETPRHITTYIHRVGRTARAGRKGTAVTVLTEQDMTLFKKILSDANKGLGEEIHVSPDIEIQHAVEYKEALAGLRSEKVKNKNQKMAEKNRVATKALIHKKQEETATVRPLTLMEKLQIKANEIVQSSKKSSETKNSKTKADKTKYQPKETKKQIIAKQLKAIEN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53734-1", "uniprot_id": "DBP6_YEAST", "id": "P53734-1", "name": "ATP-dependent RNA helicase DBP6", "aln": "--------------------------------------------------MFASRFDPSQLTAP-------AASAPEGIVGTTPPAIVPLKRQATESDNEEYGSHQDSDESSNSSSEEDEDRMQVDYGASEEDSSEVEEEESKPSTHSTVLSR------------FKQTVSLQERLGASDIAESKEDEGIEDEAAS----------THQLKQIPQPEFVKNPMNLNTNSLQFKSTGWLNTEKIYY-------DNSLIKPFSDYANELEAKLLQNICKNFSTNTFPIQSIILDSILPVLNFTLNVSKRNFTRRIGDILVNAATGSGKTLAYSIPIVQTLFKRQINRLRCIIIVPTKLLINQVYTTLTKLTQGTSLIVSIAKLENSLKDEHKKLSNLEP-------DILITTPGRLVDHLN-MKSINLKNLKFLIIDEADRLLNQSFQGWCPKLMS---------------------HLKTDKLDTLPGNVIKMIFSATLTTNTEKLNGLNLYKPKLFLKQTDKLYQLPNKLNEFNIN-------IPTAKSVYKPLILLYSICQFMAHSPIAAKILIFVKSNESSIRLSKLLQLICESRSQSSVLKNLQN-LAVSINSVNSNNSKAENKKIVANFSHHSESAGITILITTDIMSRGIDINDITQVINYDPPMSSQQYVHRVGRTARANELGSAYNLLVGRGERTFFDDLNKDLDRDGKSVQPLELDFTLLESDSELYTSSLESLKNYHNNTAQA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : * :. .. . . . . .:: . ** . . : : : **:* :: :* : *: *.*.********: **:** * * ::*.: ::*. * ** .:. . : * * : . ::.: *: * : **:::********:. .: *: *:**:******::: .*.* :: : *::*****: :.***: * *.:*:** . : * * : :. :: . : : : : : : ..: ..... . .. : :* * ** :* :****: .: *:.*:.* *:*********.. * * ..* * :.. . : : * ..: ", "identical_positions": 99, "similar_positions": 127, "identity": "11.93%" }, { "cls_id": "homologset.agr.FB:FBgn0004567", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00939-1", "uniprot_id": "FOXG1_RAT", "id": "Q00939-1", "name": "Forkhead box protein G1", "aln": "-------------------------------------------------------------------------------MLDMGDRKEVKMIPKSS------------FSINSLVPEAVQNDNHHASHGHHNS--HHPQHHHHHHHHHH-PPPPAPQPPPPPPQQ-------------QQQ--PPPAPQPPQARGAP-------AADDDKGPQPLLLPP------SAALDGAKADALGAKGE----PGGGPAELAPVGP-------------------DEKEKGAGAGGEEKKGAGEG-----------------------GKDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIG----GTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQN----------------------------SLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSD-------------------------------------------------YFTHQNQGSSSNPLIH-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60987-1", "uniprot_id": "FOXG1_MOUSE", "id": "Q60987-1", "name": "Forkhead box protein G1", "aln": "-------------------------------------------------------------------------------MLDMGDRKEVKMIPKSS------------FSINSLVPEAVQNDNHHASHGHHNS--HHPQHHHHHHHHHH-PPPPAPQPPPPPPQQ-------------QQQQ-PPPAPQPPQARGAP-------AADDDKGPQPLLLPP------STALDGAKADALGAKGE----PGGGPAELAPVGP-------------------DEKEKGAGAGGEEKKGAGEG-----------------------GKDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIG----GTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQN----------------------------SLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSD-------------------------------------------------YFTHQNQGSSSNPLIH-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55316-1", "uniprot_id": "FOXG1_HUMAN", "id": "P55316-1", "name": "Forkhead box protein G1", "aln": "-------------------------------------------------------------------------------MLDMGDRKEVKMIPKSS------------FSINSLVPEAVQNDNHHASHGHHNS--HHPQHHHHHHHHHHHPPPPAPQPPPPPQQQ-------------QPPPPPPPAPQPPQTRGAP-------AADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGE----PGGGPGELAPVGP-------------------DEKEKGAGAGGEEKKGAGEG-----------------------GKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIG----GTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQN----------------------------SLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQSSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSD-------------------------------------------------YFTHQNQGSSSNPLIH-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32031-1", "uniprot_id": "SLP2_DROME", "id": "P32031-1", "name": "Fork head domain transcription factor slp2", "aln": "-------------------------------------------------------------------------------MVKIEEGLPSSEISAHS------------LHFQHHHHPLPPTTHHSALQSPHPVGLNLTNLMKMARTPHLKSSFSINSILPETVEH-------------HDEDEEEDVEKKSPAKFPP-------NHNNNNLNTTNWGSPED--HEAESDPESDLDVTSMSPA----PVANPNESDPDEV-------------------DEEFVEEDIECDGETTDGDA-----------------------ENKSNDGKPVKDKKG-NEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIG----GSTGKLRRRTTAASR----SRLAAFKRSLIGPMFPGLAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPG----------------------------LPG-------------------------------LPGPPGPQGPPGPPPPPFVAPPTSSELYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQPPPTHHHPHLAVGQAPLSPGGDSPGPSP-------------------------------------------------QPLHKPVTVVSRNS---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQK-----FSGKYSS--YTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKN---IDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHT----PLSSSSDVNPIGDPHGDTIMMEEDEE------DENYTRGGIRPNTYTSSSNN-----------------AVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKF-----------------------------------------------GEIPAPESS----------------------------------------------------------------SIDPRGIKAQKVKKS---------------------------------------LQATSSILGESAPQLQRTQLTG--------QISTTTS-------------------------------------------------MDVTTNANVNNSSLS--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41813-1", "uniprot_id": "FKH2_YEAST", "id": "P41813-1", "name": "Fork head protein homolog 2", "aln": "MSSSNFNEMNELNMTQTNYGSTKYTAQHHQGVINAIISSLTAPDQPTTVSLQYSNDKNMATEIQAYAKLSGPNWTYYVKDLEVSIGRNTDPLNSALQENSDGVKNSYRVNIDLGPAKVVSRKHAIIKYNMNIGGWELHILGRNGAKVNFQRTHNGPNNPPIRLSSGTLLDIGGTQMMFILPDSDPVVAPICIEHLMPNLINMFGLEGNNNPLLRDIIKQSNYAKQRQLTSNQQIKGFKLYGSGGNAPFGSGANLGPSEQGIFNNNNNSKNKNGYFTSINPNYTASTTTSNTINPQAASPQGPPNTIIAANFVDSYKSSNAYPQALDFTSDLSHDENRNVKPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRISESYQQEFLNKWNTGKVGKIRRGSSVARQLQLHMAKFNSLPMEMDYRLSLNMAQPPKRQLQSHNVLEPSNNNIIEGFVQHVPSKGNLPASQQSQPPVSHQNQSQQPPPQEQRQEIQFTFADTQNRNIALARPIKTPQLQAPNSNANLNQNNMKEYKESLHPPAISISQMNRQSPNNALVSFTNACANSKIINNISDSADKSTNNNGGTKMNLPAISTSSLDENGNLEPTTTTSSGNSNSVPQTGTTTSSLAANSLRLSQPYDTLLRSPTKAFHITAMEAYTPERGSANRARSPLHSNSNNTNNNGANNSNLQTSGMENKQTGLVLDSNVLKSMESNNDNRRLTPSTSKSQNVKSSPGVWNLLQFSSTNNTPAADSGGNKRGFSINPDIKAKENENATSEKDSDSNSNDLETKDINSSPLKNQGGSTANAKELILDTDGAKISIINN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: . : . :: : . . . : : . * . : * .::: . * .. : * : : : . . : . . .:. *** ** ::* ** .:.* ::* .**::* *..:** : .****:********.* ***:: .: *** * :. . *:. *. .*:** ::.: . . . * *: : . ", "identical_positions": 47, "similar_positions": 75, "identity": "5.45%" }, { "cls_id": "homologset.agr.FB:FBgn0004573", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32305-1", "uniprot_id": "5HT7R_RAT", "id": "P32305-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-------------------------MMDVNSSGRPDLYGH-LRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFL---EVTASPAP-TWDAPPD------------NVSGCGEQIN-YGRVEKVVIGS-----------------------------------ILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQ-----------------------PESVISLNGVVKLQKEVEECANLSRLLK---------------------HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAA------GMHEALKLAERPERSEFVLQNS----------------------DHCGKKGHDT------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32304-1", "uniprot_id": "5HT7R_MOUSE", "id": "P32304-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-------------------------MMDVNSSGRPDLYGH-LRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFP---EVTASPAP-TWDAPPD------------NVSGCGEQIN-YGRVEKVVIGS-----------------------------------ILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQ-----------------------PESVISLNGVVKLQKEVEECANLSRLLK---------------------HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAA------GMHEALKLAERPERSEFVLQNC----------------------DHCGKKGHDT------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34969-1", "uniprot_id": "5HT7R_HUMAN", "id": "P34969-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-------------------------MMDVNSSGRPDLYGH-LRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS------EVTASPAP-TWDAPPD------------NASGCGEQIN-YGRVEKVVIGS-----------------------------------ILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVE-----------------------PDSVIALNGIVKLQKEVEECANLSRLLK---------------------HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAA------GMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PVG7-1", "uniprot_id": "A0A8M9PVG7_DANRE", "id": "A0A8M9PVG7-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-----------------------MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGG-----------------------------------VLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDR---VCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEE----VEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVG---------------RRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAA------GMHEALRLVERPE---VVVSG---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20905-1", "uniprot_id": "5HT1R_DROME", "id": "P20905-1", "name": "5-hydroxytryptamine receptor 1", "aln": "MALSGQDWRRHQSHRQHRNHRTQGNHQKLISTATLTLFVLFLSSWIAYAAGKATVPAPLVEGETESATSQDFNSSSAFLGAIASASSTGSGSGSGSGSGSGSGSGSYGLASMNSSPIAIVSYQGITSSNLGDSNTTLVPLSDTPLLLEEFAAGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVL-EKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPFET----MHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEILYFRCSSLNTMMRENYYQDQYGEPPSQRVMLGDER-------------------------------HGARESFL-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * : .: . . . : :... : . . . . . * * : . :*. :* :: * *: ** ** *:**:*:***:*.***:*****:**.**: ***:. : ::: :* ** ::*::::::**:******:.**.**:****.**:** * *::. * : *** :*.*:****: .:: :*:. :* :.*:*.* **:* :****::***.:**:*::**: . :.. . : . . . : . . *. *. .:: : :*:**::****::.***:******:*: *** :* :. *********:**:*** :***:*..::.:* : .:* : * : :: * ", "identical_positions": 135, "similar_positions": 137, "identity": "22.02%" }, { "cls_id": "homologset.agr.FB:FBgn0004574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61764-1", "uniprot_id": "STXB1_HUMAN", "id": "P61764-1", "name": "Syntaxin-binding protein 1", "aln": "MAPIGLKAVVGEKIMHDVIKK----VKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELV-KSRAAKVIKTLTEINIAFLPYESQVYS-LDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGE-----------------YKDNALLAQLIQDKLDAYKADDPTMG-EGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLP---IENDVYKYETSGIGEARVK--EVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSK--RMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCRVEQDLA-MGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSE------IITNMAHLGVPIVTDSTLR---RRSKPERKERISEQTYQLSRWTPIIKDIMEDTIED--KLDTKHYPYISTR---------------SSASFSTTAVS-ARYGHWHKNKAPGEYRSGPR--LIIFILGGVSLNEMRCAYEVTQANG-KWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61765-1", "uniprot_id": "STXB1_RAT", "id": "P61765-1", "name": "Syntaxin-binding protein 1", "aln": "MAPIGLKAVVGEKIMHDVIKK----VKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELV-KSRAAKVIKTLTEINIAFLPYESQVYS-LDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGE-----------------YKDNALLAQLIQDKLDAYKADDPTMG-EGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLP---IENDVYKYETSGIGEARVK--EVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSK--RMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCRVEQDLA-MGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSE------IITNMAHLGVPIVTDSTLR---RRSKPERKERISEQTYQLSRWTPIIKDIMEDTIED--KLDTKHYPYISTR---------------SSASFSTTAVS-ARYGHWHKNKAPGEYRSGPR--LIIFILGGVSLNEMRCAYEVTQANG-KWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08599-1", "uniprot_id": "STXB1_MOUSE", "id": "O08599-1", "name": "Syntaxin-binding protein 1", "aln": "MAPIGLKAVVGEKIMHDVIKK----VKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELV-KSRAAKVIKTLTEINIAFLPYESQVYS-LDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGE-----------------YKDNALLAQLIQDKLDAYKADDPTMG-EGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLP---IENDVYKYETSGIGEARVK--EVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSK--RMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCRVEQDLA-MGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSE------IITNMAHLGVPIVTDSTLR---RRSKPERKERISEQTYQLSRWTPIIKDIMEDTIED--KLDTKHYPYISTR---------------SSASFSTTAVS-ARYGHWHKNKAPGEYRSGPR--LIIFILGGVSLNEMRCAYEVTQANG-KWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07327-1", "uniprot_id": "ROP_DROME", "id": "Q07327-1", "name": "Protein ROP", "aln": "---MALKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINK-KREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLC-KSCAAGKIKTLKEINIAFLPYECQVFS-LDSPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLGEYPNVRYRSD-----------------WDRNIDLAASVQQKLDAYKADDATMG-EGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLP---IVNDVYRYTPG--PNQPDK--EVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSK--RMGSADKSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQN-YVDKLCRVEQDLA-MGTDAEGEKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQD------MVRNLSCLGINVIADSRKK---QYSVP-RKERTTESTYQMSRWTPVIKDIMEDCIED--KLDLRHFPFLEGR---------------AQNTNYHAPTS-ARYGHWHKDKGQAQVKNVPR--LIVFIVGGVSMSEMRCAYEVTNAVR-NWEVLVGSSHILSPEIFLSDLGSLSKED---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64324-1", "uniprot_id": "STXB2_MOUSE", "id": "Q64324-1", "name": "Syntaxin-binding protein 2", "aln": "MAPLGLKAVVGEKILSGVIRS----VKKDG----------EWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELG-RSRLAKAVKTLKEIHLAFLPYEAQVFS-LDAPHSTYNLYCPFRAGERGRQLDALAQQIATLCATLQEYPSIRYRKG-----------------PEDTAQLAHAVLAKLNAFKADTPSLG-EGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLD---IEQDTYRYETTGLSESREK--AVLLDEDDDLWVELRHMHIADVSKKVTELLKTFCESK--RLTT-DKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKHFKG-SVEKLCSVEQDLA-MGSDAEGEKIKDAMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSS-------LIRNLEQLGGTVTNSAGSG---TSSRLERRERM-EPTYQLSRWSPVIKDVMEDVVED--RLDRKLWPFVSDP---------------APVPSSQAAVS-ARFGHWHKNKAGVEARAGPR--LIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKTLDQKLEGVALP---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62753-1", "uniprot_id": "STXB2_RAT", "id": "Q62753-1", "name": "Syntaxin-binding protein 2", "aln": "MAPLGLKAVVVEKILSGVIRS----VKKDG----------EWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELG-RSRLAKVVKTLKEIHLAFLPYEAQVFS-LDAPHSTYNLYCPFRAGERGRQLDVLAQQIATLCATLQEYPSIRYRKG-----------------PEDTAQLAHAVLAKLNAFKADTPSLG-EGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLH---IEQDTYRYETTGLSESREK--AVLLDEDDDLWVELRHMHIADVSKKVTELLKTFCESK--RLTT-DKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKHFKG-SVEKLCGVEQDLA-MGSDAEGEKIKDTMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSN-------LIRNLEQLGGTVTNSAGSG---TSSRLERRERM-EPTYQLSRWSPVIKDVMEDVVED--RLDRKLWPFVSDP---------------APVSSSQAAVSSARFGHWHKNKAGIEARAGPR--LIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLRTLDQKLEDIALP---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15833-1", "uniprot_id": "STXB2_HUMAN", "id": "Q15833-1", "name": "Syntaxin-binding protein 2", "aln": "MAPSGLKAVVGEKILSGVIRS----VKKDG----------EWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELG-RSRLAKVVKTLKEIHLAFLPYEAQVFS-LDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIRYRKG-----------------PEDTAQLAHAVLAKLNAFKADTPSLG-EGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLD---IEQDTYRYETTGLSEAREK--AVLLDEDDDLWVELRHMHIADVSKKVTELLRTFCESK--RLTT-DKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG-SVEKLCSVEQDLA-MGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQAHSS-------LIRNLEQLGGTVTNPGGSG---TSSRLEPRERM-EPTYQLSRWTPVIKDVMEDAVED--RLDRNLWPFVSDP---------------APTASSQAAVS-ARFGHWHKNKAGIEARAGPR--LIVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIALP---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30619-1", "uniprot_id": "SEC1_YEAST", "id": "P30619-1", "name": "Protein transport protein SEC1", "aln": "---MSDLIELQRNYLIGVLNQ----IETKN----------NLKFLIIDKTVETILSYLFLTPQELLNNVTSVDLIDSPTRKGQSSIEAIYILEPTKYNINCIDADFMVRP-PKYRRCHIRFLPGLTNPIFQFFQSKRYIAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNNNCKALIPTNVRKIVGSLVSLCVITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIANAFQIAIDTYARNNPDFPPQNTERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVANVDTQKDIYHYSAENEAGEQEEKVSKLVDLYDPDWIDLKHQHIMDANEYIQGRIKELIAKNPLLVDRSNVKNTTDLLSVVAHLKDFDEERRRLILHKTLVDECLGENAERKLADISAIEQNLSGFGMDFSGEKIKHIIDDLLPALAMKEPTILDKLRYIIAYALFRGGIIELDFIKLLNFIGVTHEHENFQQYLKIFRNYDLIDFKLIKDKPKDKPFQKEWFHDTLVNDPNIYHTSRFVPAVGNILSKVIANPLLLSEQYFPYLKDKPIELLNEEEFQAGLANTSANSSSSLRNPRHKAAWTTKSSNIKKNIPRQRFFYYVIGGISIPEIKAAYDQSNLKN--RDIFIGSDEILTPTKFLDEVERLQNPREFFKFKEDQRQQVNPPDFLLREMKPVAQPVSHVHLKSQDNSPKSGTSSPKAAGSLKSEPPEKEKKRSKFSRFLKRKSHHDK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: : *:. :... : :.*::*: ::* : :.:* *: *:. *: .:::*:*:: *:. .:. : ** . *: .*: * .: :*. : : * ::::. *.:.*: *.*.:. *: .: :: : :. .:.:**. *** :** . . :* . :::: : . : :..::.** *:* ** * :*:**::: ***:***: :* *:* . : *:* * *: *:* ** .. : :: : .: : : . ** :: :: ::::* : * *.::*: : .:. :**:*: :* * .*****. : ::* * . **:* : * :::.*: * :: **: . : . :. * :. : . *: **: * : :::.. : : *. . :*::. . :. .*. . *. : ** :: :::**::: *::.**: :. ::::** .**:* :*. : *.: ", "identical_positions": 107, "similar_positions": 215, "identity": "14.38%" }, { "cls_id": "homologset.agr.FB:FBgn0004575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09951-1", "uniprot_id": "SYN1_RAT", "id": "P09951-1", "name": "Synapsin-1", "aln": "-MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSA------ASPGATPGSAAASAERASTAAPVASPAA---PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT----YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQ--RDASPGRGSHSQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGP-----------------GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPMTQGQGRQSRPVAGGPGAPPAARPPA---SPSPQRQAGPPQATRQASISGPAPPKVSGASPGGQQRQGPPQKPPGPAGP------IRQASQAGPGPRTGPPTTQQPRPSGPGPAG-RPTKPQLAQKP-SQDVPPPIIAAAGGPPHPQLNKSQSLTNAFNLPE----------------------------PAPPRPSLSQDEVKAETIRSLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88935-2", "uniprot_id": "SYN1_MOUSE", "id": "O88935-2", "name": "Synapsin-1", "aln": "-MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSA------ASPGATPGSATASAERASTAAPVASPAA---PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT----YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQPQRDASPGRGSHSQSSSPGALTLGRQTSQQPAGPPAQQRPPPQGGPPQPGP-----------------GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPVTQGQGRQSRPVAGGPGAPPAARPPA---SPSPQRQAGAPQATRQASISGPAPTKASGAPPGGQQRQGPPQKPPGPAGP------TRQASQAGPGPRTGPPTTQQPRPSGPGPAG-RPAKPQLAQKP-SQDVPPPITAAAGGPPHPQLNKSQSLTNAFNLPE----------------------------PAPPRPSLSQDEVKAETIRSLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17600-1", "uniprot_id": "SYN1_HUMAN", "id": "P17600-1", "name": "Synapsin-1", "aln": "-MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGA------HSPGATPGPGTATAERSSGVAPAASPAA---PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT----YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGP-----------------GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPA---SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP------TRQASQAGPVPRTGPPTTQQPRPSGPGPAG-RP-KPQLAQKP-SQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPE----------------------------PAPPRPSLSQDEVKAETIRSLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXI4-1", "uniprot_id": "B0UXI4_DANRE", "id": "B0UXI4-1", "name": "Synapsin-1", "aln": "-MNYLRRRLSDSNFMSNLPNGYMGDLQRPDPPQQSP---------APVLSPG----SQERRQ-------------PAPSQSTGAGFFSSISNAVKQTTAAAAATFNEATERGIGSGN-----AKILLVIDDQQTDWAKVFKGKKVHGDCDIKVEQADFSEVNLVAHATGSYSVDIEAIRSGNKIT-KCIKPDFVLVRQHAFSMAKNGDHRNIVIGLQYAGLPSVNSLHSVYNFCDKPWVFSQLSRLYKQLGPEEFPLIDQVYYPNHKEMITTPGFPVVVKMGHAHSGMGKVKVDNQYDFQDIASVVALTKT----YATSEPFIDAKYDIRIQKIGENYKAYMRTSISGNWKTNTGSAMLEQVAMSDRYRMWVDVCSEVFGGLDICAVEALHGKDGRDYIIEVVGCSMPLIGDQQDEDRALMADLVVAKMNETVPRT---SAPTTVRSQGPAVSP-------QPISQSRVPQAQQRPPPQGGPQQAAAST---------------AATRQGAPPQQRPSPQGQ-------PPAQS---QSVTSPIAQ--NPPAQQPRPNQPPQRQASQGSAAPQRPPAAQIPAQRGSPQSQRQGGPQQGGPQTGGQSPKPAGQPQQRPQ-QPRQGQPTRQPTQGGPQQ----TQDAPQPAPQGSPRPPTTQQPRPTAPGQGGPGGTRPPLQQKPQPPQKPSPDHPALSGS--PQLNKSQSLTNTFNIPET---------------------------PAAQHQSPSQDEAKAETIRNLRKSFASLFSVE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63537-1", "uniprot_id": "SYN2_RAT", "id": "Q63537-1", "name": "Synapsin-2", "aln": "MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPAP--GPGTATASAATSAASPGPERRPPPAQAPAPQPAPQPAPTPSVGSSFFSSLSQAVKQT--AASAGLVDAPAPS-AASRK----AKVLLVVDEPHTDWAKCFRGKKILGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFRPDFVLIRQHAFGMAENEDFRHLVIGMQYAGLPSINSLESIYNFCDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT----YATAEPFIDAKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDACSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITDLVISKMNQLLSRTPALSPQRPLTTQQPQSGT--------LKEPDSSKTPPQRPAPQGGPGQPQG---------------------MQPPGKVLPP-------------------RRLPS---------GPSLPPSSSSSSSSSSSSSAPQRP-----------------GGPTSTQVNASSSSNSLAEP-------------------------------QAPQAAP--------PQKPQP------------------------------------HPQLNKSQSLTNAFSFSE----------------------------SSFFRSSANEDEAKAETIRSLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64332-1", "uniprot_id": "SYN2_MOUSE", "id": "Q64332-1", "name": "Synapsin-2", "aln": "MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPAP--GPGAATASAATSAASPGPERRPPPAQAPAPQPAPQPAPTPSVGSSFFSSLSQAVKQT--AASAGLVDAPAPS-AASRK----AKVLLVVDEPHTDWAKCFRGKKILGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFRPDFVLIRQHAFGMAENEDFRHLVIGMQYAGLPSINSLESIYNFCDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT----YATAEPFIDAKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDACSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITDLVISKMNQLLSRTPALSPQRPLTTQQPQSGT--------LKEPDSSKTPPQRPPPQGGPGQPQG---------------------MQPPGKVLPP-------------------RRLPS---------GPSLPSSSSSSSSSSSSSSAPQRP-----------------GGPTTTHGDASSSSNSLAEA-------------------------------QAPQAAP--------AQKPQP------------------------------------HPQLNKSQSLTNAFSFSE----------------------------SSFFRSSANEDEAKAETIRSLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92777-1", "uniprot_id": "SYN2_HUMAN", "id": "Q92777-1", "name": "Synapsin-2", "aln": "MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQ----PAPTPSVGSSFFSSLSQAVKQT--AASAGLVDAPAPAPAAARK----AKVLLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQT----YATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSRTPALSPQRPLTTQQPQSGT--------LKDPDSSKTPPQRPPPQGGPGQPQG---------------------MQPPGKVLPP-------------------RRLPP---------GPSLPPSSSSSSSSSSS--APQRP-----------------GGPT-THGDAPSSSSSLAEA-------------------------------QPPLAAP--------PQKPQP------------------------------------HPQLNKSQSLTNAFSFSE----------------------------SSFFRSSANEDEAKAETIRSLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70441-1", "uniprot_id": "SYN3_RAT", "id": "O70441-1", "name": "Synapsin-3", "aln": "-MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPAS-----------------PATERRHPQP---------LAASFSSPGSSLFSSFSSAMKQTP-QAPTGLMEPPTPVTPVVQR----PRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIV-RSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKT----YATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKNGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPG--ASVPSPLRPWGPQTKSAKSP--GQGQLGPLLGQPQPRPPPQGGPRQAQS---------------------PQPPRSRSPSQ------------------QRLSP--------QGQQPVSPQSGSPQQQRSPGSPQLS----------------RASGGSSPNQASKPTASLSSHT------------------------------RPPVQGRSTSQQGEEPQKTASP-----------------------------------HPHLNKSQSLTNSLSTSD-----------------------------TSHRGTPSEDEAKAETIRNLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZP2-1", "uniprot_id": "SYN3_MOUSE", "id": "Q8JZP2-1", "name": "Synapsin-3", "aln": "-MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPAS-----------------PATERRHPQP---------LAASFSSPGSSLFSSFSGAMKQTP-QAPSGLMEPPTPVTPVVQR----PRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIV-RSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKT----YATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPG--ATVPSPLRPWGPQTKPAKSP--GQGQLGPLLGQPQPRPPPQGGPRQAQS---------------------PQPPRSRSPSQ------------------QRLSP--------QGQQPVSPQSGSPQQQRSPGSPQLS----------------RASGGSSPNQASKPSASLSSHN------------------------------RPPVQGRSTSQQGEEPQKSASP-----------------------------------HPHLNKSQSLTNSLSTSD-----------------------------TSHRGTPSEDEAKAETIRNLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14994-1", "uniprot_id": "SYN3_HUMAN", "id": "O14994-1", "name": "Synapsin-3", "aln": "-MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPAS-----------------PAMERRHPQP---------LAASFSSPGSSLFSSLSSAMKQAP-QATSGLMEPPGPSTPIVQR----PRILLVIDDAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKT----YATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPG--GTAPSPLRPWAPQIKSAKSP--GQAQLGPQLGQPQPRPPPQGGPRQAQS---------------------PQPQRSGSPSQ------------------QRLSP--------QGQQPLSPQSGSPQQQRSPGSPQLS----------------RASSGSSPNQASKPGATLASQP------------------------------RPPVQGRSTSQQGEESKKPAPP-----------------------------------HPHLNKSQSLTNSLSTSD-----------------------------TSQRGTPSEDEAKAETIRNLRKSFASLFSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24546-1", "uniprot_id": "SYN_DROME", "id": "Q24546-1", "name": "Synapsin", "aln": "---------MPPPPAPGQPAGAAPELSLSFGAGKTPAT---------------AAPAPPRGVSAPTS--------PAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAPAFSKD--KYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSGTRVA-RSFRPDFVLIRQPPRDGS--SDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQLQRRLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSGAGNDSHCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEISELFGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRMQNVCRPSMAQTGPGKLPSRSSVSSRAESP-TDEGVAPTPPLPAGPRPAPMGGPPPIPERTSPAVGSIGRLSSRSSISEVPEEPSSSGPSTVGG---------VRRDSQTSQSSTISSSVSRAGQRPPQTQNSVVEDAEDTMKNLRKTFAGIFGDMXEIANKKRGRTASETSSGSGPGSVPSSAGPGSGFSSSFLGKQFSFAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAGPPPPPPTNVTAVGSNANSSSGYRNSFSSSLSKDKTSYGNYGSTTSVETITRMDTNTTNIGATATEAGEASGVTAITNISNSDGIVAPTTGTITTSVTTNDWRSAIGMRSASVYSAPAAVTTVLPGDTSGYDSNSIASQGEGLNNPSDLPSYTRPSYSRSESNASKHSDLDVIFGDSKTTPASYGNGKYTRAAGSISDADMIFGGPPSNYKTDRFGASKSMSMTSGGVGSGNGSGSGLGGYKIYDSIQNAAFSDFSDSGSMSSIGSHTKRWSASKEEDDELDLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. * * :*. . .* * .: . ..*:: * :: : ***:*: ::**:* *:*::: *: :*:****:* ::.:.: . * : . *.* ::. :.::***:*:** . . : *.* ::*::*.*:*::*** *:*:* .*****::: : : ** : ***::*.::** : :. . :* *:* **.*.*:.. :::*: ** :.:*: : . *.* *.:**:*:.:::****.****:**.*::****:* *******::::::*: *** **:***:::*.:..: .*:*:::*:.. ..::.***: **: :.:** :* : . . **.* *** . *. .. . . . . . . .. . :. . . .** * :. . .. . . . :*:: . *:**:* :* ", "identical_positions": 134, "similar_positions": 183, "identity": "13.04%" }, { "cls_id": "homologset.agr.FB:FBgn0004577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11678-1", "uniprot_id": "PERE_HUMAN", "id": "P11678-1", "name": "Eosinophil peroxidase", "aln": "MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYN-WTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERCS--DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQ-----LPPCFPIKIPPNDPRIKNQ-RDCIPFFRSAPSCPQN---KNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRG--------YCSNVDPRVANVFT-LAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIG-LDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRG---VFTKRQRKALSRISLSRIICDNTGITTVSR-DIFRANIYPRGFVNCSRIPRLNLSAWRGT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K1A2-1", "uniprot_id": "A0A0G2K1A2_RAT", "id": "A0A0G2K1A2-1", "name": "Myeloperoxidase", "aln": "MKLFLALAGLLAPLAMLQTSTGATPALPGEVANSVVLDCMEEAKRLVNKAYKERRESSIKQSLRSGSASPMELLSYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDVGVTCPPQDKYRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGISLPFGWTPKVNRSGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFLTGLNCETSCLQ-----QQPCFPLKIPPNDPRIKNQ-KDCIPFFRSCPACTGS---NITIRNQINALTSFVDASGVYGSEDPLARRLRNLTNQLGLLAVNTRFQDNGRALLPFDSLHDDPCLLTNRSARIPCFLAGDMRSSEMPELTSMHTLFVREHNRLATELKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKYLPQYRS--------YNDSVDPRIANVFT-NAFRYGHTLIQPFMFRLDNQYRSTGPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIG-LDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWENPG---VFSKQQRQALATISLPRIICDNTGITTVSKNNIFMSNSHPRDFVSCNTLPKLNLASWKET--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SW46-1", "uniprot_id": "PERL_MOUSE", "id": "Q5SW46-1", "name": "Lactoperoxidase", "aln": "MKVLLHLPALLASLTLLQTAASASDDP--TAETDIIHDTVEEVKVWVNKAFLDSRDR-LKMAMTTKIHSTRHLSDYLKHAKGRTRTAIRSGQVWEESLKKLSQFLT-------NVTG--QGLDLTLLSWEAGCDPPAPTMTCNISSPYRTITGYCNNRKNPALGSANRALARWLPAEYEDGLSLPYGWTPGKMRNGFPLPQPREVSNQIAAYLNEEDVLDQKRSMLFMQWGQIVDHDMDFAPETEMGSDTYTKAQCDEHCIQ-----GDNCFPIMFPPGDPKLKTQ-GKCMPFFRAGFVCPTPP-YKSLAREQINALTSFLDASLVYSPEPSLANRLRNLSSPLGLMAVNEEVSDNGRPFPPFVKMKPSPCEVINATAGVPCFLAGDSRASEQILLATSHTLFIREHNRLATELSRLNPHWDRETLYQEARKIMGAFIQITTFRDYLPILLG-DEMQKWIPPYQG--------YNESVDPRISNVFT-FALRFGHLEIPSTVYRLDENYQPWGSESELPLHTVFFNTWRLVKDGGIDPLVRGLLAKNAKLMHQNKMMTGELRNKLFQPNHTIHGFDLASINIQRSRDHGQPGYNSWRAFCGLSQPKTLEELSAVMKNEVLAKKLMDLYGTPSNIDIWLGAVAEPLVHRGRVGPLLTCLLGQQFQRIRDGDRFWWENPG---VFTEKQRESLQKMSFSRLVCDNTGIDKVPL-NPFQANAYPHGFVDCSSIDKLDLSPWASVKE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01603-1", "uniprot_id": "PERO_DROME", "id": "Q01603-1", "name": "Peroxidase", "aln": "-MIRARDLLLLALLGFISSALGLKVSSGYHIVHNQPQSSFPNYHGFS--YLQGSAPYVIGNSLPTSPAPQNPFSSPASPPVSAYGYSFP----------------------------------------TAGRVSCAAPPAVCEKTAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGISAPT-----RSVTGDELPSARLVS---LVAFGEQDVPDPEFTLHNMQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGLDTAHKTCFAIIVPPHDPAYSQVGTECLNFVRTLTDRDSNCQYQGGPAEQLTVVTSYLDLSLVYGNSIQQNSDIREFQGGRMIVEE-----RNGAKWLPLSRNVTGDCDAVDASE--VCYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFLGGENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQIEGRLDLLSELRQVLG---SLTLSDWFNRPGIIEVGDNFDSLTRGHATQPEELTDIN--FDRQIKHFLFRRNMPFG-SDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYGDLISPP-ILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMARLLCDNGNHISSMQPEAFRTVSHSNPIIPCSNIPQVDLTKWIDQKLYATVDPSHYGKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :** * : ... . . . . : : : : : . : . . . . . :* ***: * **: . * ** :* * *..:* **:* * .* :* * ** .:. . * :: *****:: **: : . : : **.: .** ** . .*: *.*: : :*:..:**::* * **. . :*: . :: ** *: . * : : *: :** * .: *: :*:::*****:* * ***::: .*::***** * * :: ::**:.** : *:. : .:** : * .: *:*: * : : *.. : . :.* * . : ..:*.: ** : :* : :::. **. : ** ::::**.**** ..** * **** :. . . ::. : .*: * : .::*: :*. *. . .* : *:: ** : * ****:::: . *: * : * *:.*::*** . . : * : :.. :: *. : :::*: * ", "identical_positions": 140, "similar_positions": 187, "identity": "18.54%" }, { "cls_id": "homologset.agr.FB:FBgn0004580", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47728-1", "uniprot_id": "CALB2_RAT", "id": "P47728-1", "name": "Calretinin", "aln": "-------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDN---FGEKMKEFMQKYDKNSDGKIEMAELA-QILPTEENFLLCFR--QHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRP--YDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQG--MKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKKE-MNIQQLTTYRKSVMS---LAEAGKLYRKDLEIVLCSEPPM------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08331-1", "uniprot_id": "CALB2_MOUSE", "id": "Q08331-1", "name": "Calretinin", "aln": "-------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDN---FGEKMKEFMQKYDKNSDGKIEMAELA-QILPTEENFLLCFR--QHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRP--YDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQG--MKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKKE-MNIQQLTTYRKSVMS---LAEAGKLYRKDLEIVLCSEPPV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22676-1", "uniprot_id": "CALB2_HUMAN", "id": "P22676-1", "name": "Calretinin", "aln": "-------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDN---FGEKMKEFMQKYDKNSDGKIEMAELA-QILPTEENFLLCFR--QHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRP--YDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQG--MKLTSEEFNAIFTFYDKDRSGYIDEHELDALLKDLYEKNKKE-MNIQQLTNYRKSVMS---LAEAGKLYRKDLEIVLCSEPPM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07171-1", "uniprot_id": "CALB1_RAT", "id": "P07171-1", "name": "Calbindin", "aln": "-------------------MAESHLQS-----SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSP--------EMKTFVDQYGQRDDGKIGIVELA-HVLPTEENFLLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT--VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQG--IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQE-LDINNISTYKKNIMA---LSDGGKLYRTDLALILSAGDN-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12658-1", "uniprot_id": "CALB1_MOUSE", "id": "P12658-1", "name": "Calbindin", "aln": "-------------------MAESHLQS-----SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSP--------EMKSFVDQYGQRDDGKIGIVELA-HVLPTEENFLLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT--VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQG--IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQE-LDINNITTYKKNIMA---LSDGGKLYRTDLALILSAGDN-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05937-1", "uniprot_id": "CALB1_HUMAN", "id": "P05937-1", "name": "Calbindin", "aln": "-------------------MAESHLQS-----SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSP--------EMKTFVDQYGQRDDGKIGIVELA-HVLPTEENFLLLFRC-QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT--VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQG--IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQD-LDINNITTYKKNIMA---LSDGGKLYRTDLALILCAGDN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41044-1", "uniprot_id": "CAB32_DROME", "id": "P41044-1", "name": "Calbindin-32", "aln": "MDSAAAAAAKRVQIEKAHNFMRQYRDPESRELKKLSANQFMDVWAHYDKDGNGYIEGTELDGFLREFVSSANATDISPEAVTDTMLEELKSCFMEAYDDNQDGKIDIRELA-QLLPMEENFLLLFRFDNPLESSVEFMKIWREYDTDNSGYIEADELKNFLRDLLKEAKKINDVSEDKLIEYTDTMLQVFDANKDGRLQLSEMAKLLPVKENFLCRQVFKGA-TKLTKEDIEKVFSLYDRDNSGTIENEELKGFLKDLLELVKKDDYDAQDLAAFEETIMRGVGTDKHGKISRKELTMILLTLAKISPDDEE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6R556-1", "uniprot_id": "SEGN_RAT", "id": "Q6R556-1", "name": "Secretagogin", "aln": "-------------------MDNAHRQT----QAHLDAACFWQIWQRFDKDEKGYIKETELDAFFDDLLAKFGIEDTLMEEN----VQKMKEQLMVGHDISKEGRILMKELASMFLSEDENFLLFFRLETPLDNSVEFMQIWRKYDADSSGFISAAELSNFLRDLFLHHKKV--ISEAELEEYTSTMEKIFDRNKDGRLDLNDLARILALQENFLLQFKMDASSTEERKRDFEKIFAHYDVSKTGALEGPEVDGFVKDMMELVQPS-ISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WD9-1", "uniprot_id": "SEGN_MOUSE", "id": "Q91WD9-1", "name": "Secretagogin", "aln": "-------------------MDNARRKT----PARLDAACFWQIWQRFDKEEKGYIRETELDAFFDHLLAKSGTEDTLMEEN----VQKVKEQLMTSHNVSKEGRILMKELASMFLSEDENFLLFFRLETPLDNSVEFMQIWRKYDADSSGFISAAELCNFLRDLFLHHKKN--ISEAELEEYTSTMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSTEERKRDFEKIFAHYDVSKTGALEGPEVDGFVKDMMELVQPS-ISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76038-1", "uniprot_id": "SEGN_HUMAN", "id": "O76038-1", "name": "Secretagogin", "aln": "-------------------MDSSREPT----LGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKAN----LHKVKQQFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDADSSGFISAAELRNFLRDLFLHHKKA--ISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPS-ISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJX1-1", "uniprot_id": "SEGN_DANRE", "id": "Q5XJX1-1", "name": "Secretagogin", "aln": "-------------------MDSA--------FANLDAAGFLQIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDER----VQQIKKSFMSAYDATFDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKK--IPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDMMELVRPS-ISGGDLDKFRECLLTHCDMNKDGKIQKSELALCLGLKHKP------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * ::* ::* : .**:. .**: :: .: . . . :: . :*:: : *** .*. :***** ** : .. ***: **:**:* **:*.: ** .** **: . :: :* *** : ::** * **:* *.:::::*.::**** : :.. .::: * ** . .* :: *:..::**: * : . . :: :.: :: . **: :.:* : * ", "identical_positions": 65, "similar_positions": 91, "identity": "20.83%" }, { "cls_id": "homologset.agr.FB:FBgn0004581", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZKH1-1", "uniprot_id": "A0A8I5ZKH1_RAT", "id": "A0A8I5ZKH1-1", "name": "3'-5' RNA helicase YTHDC2", "aln": "MSRPSSVSPRPPAPSGGGTGGGGGG-----------PASCGPGSGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQVPVKRGES-EFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQREEKQQTTLTEWYSAQENTFKPESQRQRAVASVSEEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDVDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFTSQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGNDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAILIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCR-PGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCTIADFLMKAPEPPPALIVRNAVQMLKTIDAMDAWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQK-----------RAAMLCRKRFTAGTFSDHMALLRAFQAWQKARSDGWERAFCEKN--FLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENVVLTGPKEKKVRFHPTSVLSQPQYKKIPPANGQAAAIQALPTDWLIYDEMTRAHRIANIRCCSAVTPVTVLVFCGPARLTSNALQEPSSFRADGIPNDSSDSEMEDRTTANLAALKLDEWLNFKLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDGSTAAERVLMKSPSPALHPPQKYKDRGILHPKRSTDDRSDQSSVKSTDSSSYPSPCASPSPPSSGKGSKSPSPR-PNMPIRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNR---AFWESSMVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKTTSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RR83-1", "uniprot_id": "YTDC2_MOUSE", "id": "B2RR83-1", "name": "3'-5' RNA helicase YTHDC2", "aln": "MSRPSSVSPRPPAPSGGGTGGGGGGSGGGGGGGGGGPASCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQVPVKRGES-EFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQREEKQQTTLTEWYSAQENTFKPESQRQRAVASVSEEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDVDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFTSQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGNDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAILIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCR-PGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCTIADFLMKAPEPPPALIVRNAVQMLKTIDAMDAWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQK-----------RAAMLCRKRFTAGTFSDHMALLRAFQAWQKARSDGWERAFCEKN--FLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENVILTGPKEKKVRFHPTSVLSQPQYKKIPPANGQAAAIQALPTDWLIYDEMTRAHRIANIRCCSAVTPVTVLVFCGPARLASNALQEPSSFRADGIPNDSSDSEMEDRTTANLAALKLDEWLNFKLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSTADTEFADGSTTGERVLMKSPSPALHPPQKYKDRGILHPKRSTDDRSDQSSVKSTDSSSYPSPCASPSPPSSGKGSKSPSPR-PNMPIRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNR---AFWESSMVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPQVGEQLLQLWERLPLGEKTTSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6S0-1", "uniprot_id": "YTDC2_HUMAN", "id": "Q9H6S0-1", "name": "3'-5' RNA helicase YTHDC2", "aln": "MSRPSSVSPRQPAPGGGGGGG---------------PSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRGES-EFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCR-PGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQK-----------RAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCEKN--FLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSLKSTDSSSYPSPCASPSPPSSGKGSKSPSPR-PNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNR---AFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKNTTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q954-1", "uniprot_id": "A0A8M9Q954_DANRE", "id": "A0A8M9Q954-1", "name": "RNA helicase", "aln": "MSRGGQKSNMSSSKQ-------------------------HQASSLKAKGFRDIRIDEEVKIAVNIALERFQYSDEKELDFPSSLTNSERAFIHRLAQSLGYISKSRGKGCSRFLTVRKKDGMEAQRSSMSCSLSPSCRALVQSLMQRFPISSRERSQLQPHAERG-LQSPPDTTDSKSRTSGRLSHGIPQVPPRRSSAPELDAFRKALPVYELQEQIIQSIRDHQVVLVLGETGSGKTTQIPQFLLDDCSATASPCRIFCTQPRRLATIAVAERVAAERGENIGQTVGYQIRLESRVSPKTLLTFCTSGVLLRTLMAGDEALSTVTHVIVDEVHERDGLTDFLLTKMKEVLQKMPNLRLVLSSAALDVSLFMRYFGSCPVIHIKGCPYEVKQLFLEDILRSTAYTNKDMIKYKKEAQKEESQQCSLSEWCERDVPQADPP---ERPTVCVLQDNQLLDDGGDSVFSQMSEKDVSSLEPWLLREMDSCISSIFLNQDADAFTQLFNLILNENISVDYRHSETSATALMVSAGRGFVSHTEQLLNMGANINIKASNGWTALDWAKHFKQTEAVDLLESHIWCAEASPQDEASLLQNSSCELSCEDQELLKAYHHSFDDEKVDLQLILHLLHSICQSSDQGAVLIFLPGYDEIVSLRDQILFDDKRFTEHQQRFQVFVLHSSMQTSDQKKVLKSTPKGVRKIILSTNIAETSITVSDVVFVIDSGKVKEKAYDALNNVTMLKMVWISKASALQRKGRAGRCR-PGVCFHLFSRLRFSNMLEHQIPQLLRMPLQELCLHTKLLAPINCPVAEFLSRAPEPPHINTVKHAVQMLKTIDAMDPWENLTELGLHLADLPVEPHLGKMVLCAVVLKCLDPVLTIACTLAHREPFVLPAQAAQR-----------RVAMLCRRRFTANTFSDHMALLRAFQAWQKARSDGWERAFCEKN--FLSQATMEIIVSMRTQLLGQLRATGFVRARGGGDIRDVNQNSENWAVVKAALVAGMYPNLIHRDG--LSLSGEKEKKVRLHPTSVLSQPQYKKIPPANGQAAAVDSLPTDWLIYDEMTRAHRIASVRCCTAVTPLTIALFGGGAKLPSSALQEAVLQRGS---ADSSDSEVEDQCSARQAHLTLDHWINFRLDPETAELVFGLRQRWQSVFLRRIRSPSKACSQLDESTIRTLVSVLSAEEQSAGLQQPTGIGQRPRPVSAEDS--SSYTHTHGRSRNTADTPQQEATASPDRPRLAS---------QLKNPRMHHSRHQEEDLAPCG------------ISEGPTSPSTALVSMSACVRAPHSSVRYFIMKSSNPRNIELSQQRSVWSTTPNNEQKLNR---AFQNSSAVFLVFSVQGSGHFQGYARMTSAVSSERCLDFGSSGLGGVFSVQWIHTESLAFQLTHKLLNPWNDNKKVQISRDAQELEPHTGNQLLQLWEKL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1I2-1", "uniprot_id": "BGCN_DROME", "id": "Q9W1I2-1", "name": "Protein benign gonial cell neoplasm", "aln": "--------------------------------------------------MNHIIQDKYIPQQLLYFLAGRRCCQQ----FPCTFRTSEHEAFANNARSLGLRSQVVHVNGNSCVKVYKQACRHYLEEPKTLVLSSGATLNMFTLLSRKSLMGKEDLELYADLVSMKANASDLPSLHLPLPAIRP-------PNLRFWTEAQLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRSLTS--QQFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHS------------------------------------------CIALAGIHKGPDIYKEIPEAFRANNPRN----------EQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVD---YDLIIDIMYLLRTKPEYSPGE-----------------YSPGNILIILPTYYHIVKLNYMILS--HCLTGSLQECSIFLLYDNMRN-DYLQALVNASDETVKVVLATDIIESLCLKVPFKYQIDTACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGDVQCFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLLSPN-TIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVDTRKSSLKSAFSGNVSMHPNTVLR----DFLEPLN---ISAQSFRTPWIVCNRQK-----SHIVYATLVVPLAVAMFSGHPRIRLSPICDS-----------------EMSLTDRNVNVFIDEWIWMVMSKATAEMVMRTRYYFFKMYHDLLKHCSELDMWRRDCEPVSQYTVLTDTLSKIFESEDGFVG------------------------------------------------------FFKPPPITFLP-------------------------TPQLPSLYLLSVNAHFSWAREVEENMLSKPHHFNSHFIERQFFVLYAGGDCEEFHSRNTPAFIESVLGKFVRPIDTPNRHIFVILYRKDPDMMLSISRAKFVNGVFMLQEYFRNNIPVFEILDACVSLNVQTPVFDGRLMSALIDKRVGNLIMELFAFRHHWIHKR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* *: : : * : :: **.:: .:*: : . ::*** *: . . :.* *: . . : *: . : :*:.* .: .:* :* .. : . . .: * * * : * :: .. .::*:: : :*:: . .*:. :* .:**** . :*:* : : : : ::*.* *.:*:*:* *: * **..*:: :.* :**:* : . : .::*::*::** :* :*:**:::: *.. .*:::* * : . * :**. : : * . .: : *:: . : . :: .: ::. :: ..: .:** *:. *: .: : : .*:**** *. **: .:: . ..: . *: ***: *:. * : * :*:*:*: :..::: :* : **:: . .* . * :**:** * .** *. ** : :: :. .:*:*:..*:. * :.* ... . *::*:*:* *: . : **:. :: :*: . :: *::* : ::*: : **:*:*: :.:: * . *.* * *:::** .***:* ::::* : .** *::***:**.**.:* *::* ** :* *:**. :**:*:: .::*:****:***..:*: :*: :* . * :: . ****: ::* :: **: : : :.: *: :. ** : .:*::::..***:.::::** .:.::* * ** :*****..*****: * *.. . :* :** :** . : * * : .:: * *:: :. . : : .: *.*::: :* * .:: ..: :. * : . . : :*.*: : :. :*.::: * : .:: :: *: :. : :**: .. .: :* * : . * ** * .. .. . :: *. : .. :.:* : : . *. .* ** :* :* .:: ..:. . . . . .. * .: ::::.: *:: . :. :. .: . :: .*: :::*: ", "identical_positions": 237, "similar_positions": 446, "identity": "16.19%" }, { "cls_id": "homologset.agr.FB:FBgn0004583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96NE9-1", "uniprot_id": "FRMD6_HUMAN", "id": "Q96NE9-1", "name": "FERM domain-containing protein 6", "aln": "--------------------------------------MNKLNFHNNRVMQDRRSVCIFLPND---ESLNIIINVKILCHQLLVQVCDLLRLK---DCHLFGLSVIQNNEHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGRLISDRAARYYYYWHLRKQVLHSQCV--LREEAYFLLAAFALQADLGNFK----------------------------------RNKHYGKYFEPEAYFP-------------------------SWVVSKRGKDYILKHIPNMHKDQFALTASEAHLKYIKEAVRLDD-VAVHYYRLYKDKRE-IEASLTLGLTMRGIQIFQNLDEEKQL---LYDFPWTNVGKLVFVGKKFEILPDGLPSARKLIYYTGCPMRSRHLLQLLSNSHRLYMNLQPVLRHIRKLEE--NEEKKQYRESYIS-----------------------------------------------------------------------------------DNLDLDMDQLEKRSRASGSSAGSMKH-KRLSRHSTASHSSSHTSGIEADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDLQDDEIEMLVDDPRDLEQMNEESLEVSPDMCIYITEDMLMSRKLNGHSGLIVKEIGSSTSSSSETVVKLRGQSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDEEGLYCNSCLAQQCINIQDAFPVKRTSKYFSLDLTHDEVPEFVV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0V9-1", "uniprot_id": "FRMD6_MOUSE", "id": "Q8C0V9-1", "name": "FERM domain-containing protein 6", "aln": "--------------------------------------MNKLTFHNNKAMQDRRRVCIFLPND---KSVSIIINVKILCHQLLVQVCDLLRLK---DSHLFGLSVIQNNEHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGKLISDRIARYYYYWHLRKQVLHSQCV--LREEAYFLLAAFALQADLGNFK----------------------------------RKLHHGDYFEPEAYFP-------------------------AWVVSKRGKDYILKHIPNMHKDQFALTASEAYLKYIKEAVRLDD-VAIHYYRLYKDKRE-AEGSLTLGLTMRGIQIFQNLEEEKQL---LYDFPWTNVGKLVFVGKKFEILPDGLPSARKLVYYTGCPTRSRHLLQLLSNSHRLYMNLQPVLRHLRKQEE--NEEKKQYRESYIS-----------------------------------------------------------------------------------DNLDLDMDPLEKRSRASGSSAGSVKH-KRLSRHSTASHSSSHTSGIEADTKPRDPGPEDSCSGSAMHRKLKTCSSMTSHGSSHTSGVESGGKDRLEEDSQDEEIEMLVDDPRDLEPMPEESLEVSPEMCIYITEDMLLSRKLNGHSGLIVKEIGSSTSSSSETVVRLRGQSTDSLPQTICRKPKTSTDRHSLSLDDIRLYQKDFLRIAGLCQDTAQSYTFGCGHELDESGLYCNSCLAQQCVNIQDAFPVKRASKYFSLDLTHDEVPEFVV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VII0-1", "uniprot_id": "FRMD6_RAT", "id": "Q8VII0-1", "name": "FERM domain-containing protein 6", "aln": "--------------------------------------MNKLTFHNNKVMQDRRRVCIFLPND---KSVSIIINVKILCHQLLVQVCDLLRLK---DSHLFGLSVIQNNEHVYMELSQKLYKYCPKEWKKEASK--------GIDQFGPPMIIHFRVQYYVENGKLISDRIARYYYYWHLRKQVLHSQCV--LREEAYFLLAAFALQADLGNFK----------------------------------RKVHHGDYFEPEAYFP-------------------------AWVVSKRGKDYILKHIPNMHRDQFALTASEAYLKYIKEAVRLDD-VAIHYYRLYKDKRE-VEGSLTLGLTMRGIQIFQNLEEEKQL---LYDFPWTNVGKLVFVGKKFEILPDGLPSARKLVYYTGCPTRSRHLLQLLSNSHRLYMNLQPVLRHLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AZA5-1", "uniprot_id": "A0A8M3AZA5_DANRE", "id": "A0A8M3AZA5-1", "name": "", "aln": "---------------------------------------------MSVPTKQERTVCVLLPNK---ETLDITVGVKATGQDVFHRVCELLGVR---ELHYFGLTLVKNNEHIFLDLEEKLAKYFPKEWKQDSGKQ-------GSHRRSIPPLLCLKVQYYVENGRLICERKARKLYYYDLRERVLRSECR--QQEEVYFQLAGFALQADHSDHSS-------------------------------EGQSHGHAMYFQPKEYFP-------------------------PWIIAKRGIDYLLCHGPKVHKELWGMSCRDAVLLFIRESCRLED-VPVTFYRLQKDKKE-EKGSALLGLTLRGMQVFQEVNNVRDL---LYDFPWFHVGRLTFLGKKFEIQPDGLPSARKLVYYTGSAFRSRHLLLHLSSCHRLYLSLQPALKHLRQLEE--TEEKKRYRESYIS-----------------------------------------------------------------------------------DELDLDQP----------CSEGSP----RLSRHSTSS------SGIEADTR------QNSVSVEMVSVEEKEKSSIN------TSSTAQSHEEHWQETDSQEPGEVSVDDPVDLLRLAELLEGVS----------------VDCPTIQSVKDSKDQHMSSVTGKDQTDLSDPDGLKQVLNQKLSNPSDCYNLSLEDVRQLSPLLPLGTPTAPNASIGYTFALPHSP------TNPCPDDTSLCVQ------RPTNCLSLARLDDNQPLELVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N878-1", "uniprot_id": "FRMD1_HUMAN", "id": "Q8N878-1", "name": "FERM domain-containing protein 1", "aln": "MAVPPRGRGIDPARTNPDTFPPSGARCMEPSPERPACSQQEPTLGMDAMASEHRDVLVLLPSR---EQLRLAVGVKATGRELFQQVCNVASIR---DAQFFGLCVVRNNEYIFMDLEQKLSKYFSKDWKKERNE--------GNEKPRAPFVAFLRVQHYVENGRVISDHRARHLYYCHLKERVLRSQCA--HREEAYFLLAACALQADLGEHR----------------------------------ESAHAGRYFEPHSYFP-------------------------QWIITKRGIDYILRHMPTLHRERQGLSPKEAMLCFIQEACRLED-VPVHFFRLHKDKKE-GRPTVILGLALRGVHIYQ--------------------------GKKLEIQLDGLPAAQKLVYYTGCTWRSRHLLHLLRASHQLHLRVRPTLQQLRQREE--AEEKQHYRESYIS-----------------------------------------------------------------------------------DELELDLAS---RSFPGSGVSSQHCP-HCLSRHSADSHGSSYTSGIKANSWLR------------------------------------------------ESREMSVDVPLEVHGLHEKEPSSSP---------------RTSRSHPSTRGDSQATRQEPCTQVRTRGQSAEAVHQIQEMTAGVSEEQHSHGLDDMQLHQLALHPAP-----TSLSHTFHRALDCR----LAGPCETRATLPSK------RSSNCLALDLFGEAPPQEFVV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07436-1", "uniprot_id": "EXPA_DROME", "id": "Q07436-1", "name": "Protein expanded", "aln": "----------------------------MRAFCTVSAPLEVCASSAEQLSPGSRFLALRLLGQQQPKTLYFLVDAKSRVREVYTQTCLHFATQGMLDTELFGLAVLIDGEYMFADPESKLSKYGPKSWRSSHTHG-------LDANGRPLLELHFRVQFYIESPFMLKDETSRHNYYLQLRHNILQRDLPREQAEQALVFLAGLALQADLGDAPPGTSNSKDDSGEETSASPSNGGRGLSATTTLPKISKRANERMLRLSTYVASTSKRETIPLPPSLPPNGADYYRIEDYLPSGLHTPWARSAMRACHREHLGMATAEAELLYIQQACSLHETINAHTYRMRLAKSEQGSGSAWFVVYAKGIKILGGESTNSSSNPETTTFLWPNITKLSFERKKFEIR----SGESRITLYAASDEKNKLLLTLCKDTHQWSMKLAARLKEVSKREEEEAAESQRLHASYACSRSLLLPYKSKNEQRISVISSTSSNTTSGIVSDRVHSEDELEIMINTPPAPLAAPSTESLALAHLLDRPSVSRQTSSVGQMSLKDLEEQLAALSVRPQDASSNGATIVTNSSVQRNSMGTTANDSSTATDSPSSQHNIGSQCSSTCSTVVVTSPVNGAGASSSGAPIPVHSTSSSLELGFSHTAQNSALSETSPDDFLSTSAREETESVSGASGVYTLAHGAPPTETSGVYTMHSSELTGQSSEIAESEKSSHYGMFQPQKLEETHVQHSDSVDGKKKEDFRPRSDSNVSTGSSFRGDGSDPTDNKHSLLSAEELTNLIVGRGTYPSRKTVSSSLHSDCDYVTLPLGDQGEEEVDQPPAPPPPYSARHEKTGLCGPPIAKPIPKPIAVVAPKPDSPPCSPPVPPAPIPAPPPAIRRRDPPPYSISSKPRPTSLISVSSSAHPAPSAAGSMSSLKSEEVTARFITTRPQISILKAHTSLIPDGAKPSYAAPHHCSSVASSNGSVCSHQLSQQSLHNSNYAGGSQASLHHHHVPSHHRHSGSAAIGIVPYGLHKSTASLHHQQSCVLLPVIKPRQFLAPPPPSLPRQPPPPPPPNHPHLASHLYEREMARKQLELYQQQLYSDVDYVIYPIQDPAVSQQEYLDAKQGSLLAAMAQAAPPPPHHPYLAMQVSPAIYRSTPYLPLTLSTHSRYASTQNLSDTYVQLPGPGYSPLYSPSMASLCSSYEPPPPPPLHPAALAAAAAAGAGSSSSSMFARSRSDDNILNSLDLLPKGKRLPPPPPPPYVNRRLKKPPMPAPSEKPPPIPSKPIPSRMSPIPPRKPPTLNPHHANSPLTKTSSGAQWAGERPRPDLGLGLGLNRGNNSILAQLQASMVAQSHAQAQAQALDIALLREKSKHLDLPLISALCNDRSLLKQTKVVINPKTGQEMPTSSAQPSGATTNGVANSSAGAGTLSKARKGSTVSHRHPQDKLPPLPVQQLAEANNYVIDPAVMMKQQQQQQQHNKTS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : * . : : : :..* ::: :.* : : . *** :: :.*::: : ..** ** .*.*:.. . . ::**.*:*. :: :. :* ** .*:..:*: : *:. . **. ***** .: . :. *.. :: : : *:: .:: :* * :*::: *.: : :*: * * : : : :*::: **:** .. :: *:.. :.: ** *: : : . *:.: ", "identical_positions": 50, "similar_positions": 107, "identity": "3.41%" }, { "cls_id": "homologset.agr.FB:FBgn0004584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43138-1", "uniprot_id": "APEX1_RAT", "id": "P43138-1", "name": "DNA repair nuclease/redox regulator APEX1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPK-RGKR-AAAEDGEEPKSEPETKKSKGAAKKTEKEAAG----------------------------------------------------------------EGPVLYEDPPDQKTSASGKSAT--------------------LKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLP-AELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCP---------------LKVSYGIGEEEHDQEGRVIVAEFESFILVTAYVP--NAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFT------PQERQGFGEMLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28352-1", "uniprot_id": "APEX1_MOUSE", "id": "P28352-1", "name": "DNA repair nuclease/redox regulator APEX1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPK-RGKK-AAADDGEEPKSEPETKKSKGAAKKTEKEAAG----------------------------------------------------------------EGPVLYEDPPDQKTSPSGKSAT--------------------LKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLP-AELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCP---------------LKVSYGIGEEEHDQEGRVIVAEFESFVLVTAYVP--NAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFT------PQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27695-1", "uniprot_id": "APEX1_HUMAN", "id": "P27695-1", "name": "DNA repair nuclease/redox regulator APEX1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPK-RGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAG----------------------------------------------------------------EGPALYEDPPDQKTSPSGKPAT--------------------LKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLP-AELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCP---------------LKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVP--NAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFT------PQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0MTA1-1", "uniprot_id": "APEX1_DANRE", "id": "A0MTA1-1", "name": "DNA repair nuclease APEX1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPK-RAKKNEEGVDG-------EADNGTAAAKKEKKGKEP----------------------------------------------------------------EAPILYEDPPEKLTSKDGRAAN--------------------MKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALP-ADITGMPEYPHKYWAGSEDKEGYSGVAMLCKTEP---------------LNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVP--NASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFT------PEEREGFTQLLEAG-FTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27864-1", "uniprot_id": "RRP1_DROME", "id": "P27864-1", "name": "Recombination repair protein 1", "aln": "MPRVKAVKKQAEALASEPTDPTPNANGNGVDENADSAAEELKVPAKGKPRARKATKTAVSAENSEEVEPQKAPTAAARGKKKQPKDTDENGQMEVVAKPKGRAKKATAEAEPEPKVDLPAGKATKPRAKKEPTPAPDEVTSSPPKGRAKAEKPTNAQAKGRKRKELPAEANGGAEEAAEPPKQRARKEAVPTLKEQAEPGTISKEKVQKAETAAKRARGTKRLADSEIAAALDEPEVDEVPPKAASKRAKKGKMVEPSPETVGDFQSVQEEVESPPKTAAAPKKRAKKTTNGETAVELEPKTKAKPTKQRAKKEGKEPAPGKKQKKSADKENGVVEEEAKPSTETKPAKGRKKAPVKAEDVEDIEEAAEESKPARGRKKAAAKAEEPDVDEESGSKTTKKAKKAETKTTVTLDKDAFALPADKEFNLKICSWNVAGLRAWLKKDGLQLIDLEEPDIFCLQETKCANDQLP-EEVTRLPGY-HPYWLCMPG--GYAGVAIYSKIMP---------------IHVEYGIGNEEFDDVGRMITAEYEKFYLINVYVP--NSGRKLVNLEPRMRWEKLFQAYVKKLDALKPVVICGDMNVSHMPIDLENPKNNTKNAGFT------QEERDKMTELLGLG-FVDTFRHLYPDRKGAYTFWTYMANARARNVGWRLDYCLVSERFVPKVVEHEIRSQCLGSDHCPITIFFNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38207-1", "uniprot_id": "APN2_YEAST", "id": "P38207-1", "name": "DNA-(apurinic or apyrimidinic site) endonuclease 2", "aln": "---------------------------------------------------------------------------------------------------MSSSENTLLDGKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQELKTEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQVVKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELDSEGRCVMVELACGIVIISVYCPA-NSNSSEEGEMFRLRFLKVLLRRVRNLDKIGKKIVLMG----------------------------------------------------------------DVNVCRDLIDSADTLEQFSIP---------------------ITDPMGGTKLEAQYRDKAIQFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTVWNMLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSDLDILDDRIEPGTTQVPIPKFEARYKYNLRNHNVLEMFAKKDTNKESNKQKYCVSKVMNTKKNSNIKNKSLDSFFQKVNGEKDDRIKESSEIPQQAKKRISTPKLNFKDVFGKPPLCRHGEESMLKTSKTSANPGRKFWICKRSRGDSNNTESSCGFFQWV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..: . * * : .: .. . . . . *.* :...:: : . : : ::. ** . : *: : . * :. .. * * . : .: :: : .: : .:: * :: : : : .. ... : . : : :.* ** .: *:: : . * *. .* . :..: : . . : . . . .. * : :. ", "identical_positions": 20, "similar_positions": 90, "identity": "2.83%" }, { "cls_id": "homologset.agr.FB:FBgn0004587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VE97-1", "uniprot_id": "SRSF4_MOUSE", "id": "Q8VE97-1", "name": "Serine/arginine-rich splicing factor 4", "aln": "---MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG--FVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRR--DGS------------------YGSGRSGYG-------------YRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKS--RSRSQERRAEEERRRSVSRARSQEKSRSQEKSLLKSR--SRSRSRSRSRSKDKRKGRKRSRDESRSRSRS--KSERSRKHSSKRDSKVSSSSSSSKKKKDTDHSRSPSRSVSKEREHAKAESGQRGSRAEGESEAPNPEPRARSRSTSKSKPNVPAESRSRSKSAS-------KTRSRSKSPSRSASRSP---SRSRSRSHSRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V798-1", "uniprot_id": "G3V798_RAT", "id": "G3V798-1", "name": "", "aln": "---MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG--FVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRR--DGS------------------YGSGRSGYG-------------YRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKS--RSRSQERRAEEERRSSTSRGHSQEKSLLKSRSRSRSK--VGSRSRSRSKSKDKRKGRKRSREESRSRSRS--KSERSRKHSSKRDSKVSSSSSK-KKKGDTDHSRSPSRSVSKEREHATAEPGQRESRAEGESEGPNPEPRARSRSTSKSKPSLPAESRSRSKSAS-------KTRSRSKSPSRSASRSP---SRSRSRSHSRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08170-1", "uniprot_id": "SRSF4_HUMAN", "id": "Q08170-1", "name": "Serine/arginine-rich splicing factor 4", "aln": "---MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG--FVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRR--DGS------------------YGSGRSGYG-------------YRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKE-KSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS-------KTRSRSKSRSRSASRSP---SRSRSRSHSRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TWW8-1", "uniprot_id": "SRSF6_MOUSE", "id": "Q3TWW8-1", "name": "Serine/arginine-rich splicing factor 6", "aln": "---MPRVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYG--FVEFEDSRDADDAVYELNSKELCGERVIVEHARGPRR--DRDGYS---------------YGSRSGGGG----------YSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR-RRS--------------------RSRSRRSSRSRSRSISKSRSRSR---SRSKG-----RSRSRSK-GRKSRSKSKS------------------------------KPKSDR---------------------------------GSHSHSRSRSKDKY-------GKSRSRSR-----SRSPKENGKGDIK----------------SKSRSRS------------------------------QSRSHSPLP-----APPSKARSMSP---------PPKRAS-----RSRSR---SRSRSRSSSRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6S8-1", "uniprot_id": "SRSF6_RAT", "id": "G3V6S8-1", "name": "Serine/arginine-rich splicing factor 6", "aln": "---MPRVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYG--FVEFEDSRDADDAVYELNSKELCGERVIVEHARGPRR--DRDGYS---------------YGSRSGGGG----------YSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR-RRS--------------------RSRSRRSSRSRSRSISKSRSRSR---SRSKG-----RSRSRSK-GRKSRSKSKS------------------------------KPKSDR---------------------------------GSHSHSRSRSKDKY-------GKSRSRSR-----SRSPKENGKGDIK----------------SKSRSRS------------------------------QSRSHSPLP-----APPSKARSMSP---------PPKRAS-----RSRSR---SRSRSRSSSRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13247-1", "uniprot_id": "SRSF6_HUMAN", "id": "Q13247-1", "name": "Serine/arginine-rich splicing factor 6", "aln": "---MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYG--FVEFEDSRDADDAVYELNGKELCGERVIVEHARGPRR--DRDGYS---------------YGSRSGGGG----------YSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR-RRS--------------------RSRSRRSSRSRSRSISKSRSRSR---SRSKG-----RSRSRSK-GRKSRSKSKS------------------------------KPKSDR---------------------------------GSHSHSRSRSKDEY-------EKSRSRSR-----SRSPKENGKGDIK----------------SKSRSRS------------------------------QSRSNSPLP-----VPPSKARSVSP---------PPKRATSRSRSRSRSK---SRSRSRSSSRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8T5-1", "uniprot_id": "A0A8M2B8T5_DANRE", "id": "A0A8M2B8T5-1", "name": "", "aln": "---MPRVYIGRLSYHVREKDIQRFFSGYGKLLEVDLKNGYG--FVEFEDTRDADDAVYELNGKELCGERVMVEHARGPRR--DRDSYGGGGGGGGGGGGGGGYYGGGGGGGGGGGGGGGRSGYSSRSRTGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERANEGVIEFRSYSDMRRALEKLDGTDINGRKIRLVEDKPRR--RRSYSGSRSRSRSR-RRS--------------------RSRSRRSSRSRSNSRSRSRSRSRRHRSRSRS-----GRRSRSKSGHKSRSKSPS------------------------------SKSRSR---------------------------------NRKSHSRSRSRTHK-------SRSRSTSRK----SRSRSDDRKSRSK----------------STSKVKSD----------------RGRSKEKSVSKKSRSRSASPMENGDGERPKSASRSPSPQAEQSKYKSPDRHSRSRSKSASRSK---SRSRSRSASQD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26686-2", "uniprot_id": "SRR55_DROME", "id": "P26686-2", "name": "Serine-arginine protein 55", "aln": "-MVGSRVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYG--FVEFEDYRDADDAVYELNGKELLGERVVVEPARGTARGSNRDRYDDR-------------YGGRRGGGG-----------GRYNEKSSSRYGPPLRTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRGGRSGGGGGSGRGRSRSSSSRS--------------------RSRSRRRSRSRRSSHSRSKSRSR---SKSRG------GRSKSKSPVKSRSRSRS-----------------------------------R---------------------------------SNKSRDVSKSKSKS--------HSRTRSR-----SPKRERDSRSRSR--------------SVSKRESRS------------------------------RSRSKSIHR-----DSRSRDRSASAE--------NKSRSRSRSRSASPKNGNASPDRNNESMDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01560-1", "uniprot_id": "NOP3_YEAST", "id": "Q01560-1", "name": "Serine/arginine (SR)-type shuttling mRNA binding protein NPL3", "aln": "MSEAQETHVEQLPESVVDAPVEEQHQEPPQAPDAPQEPQVPQESAPQESAPQEPPAPQEQNDVPPPSNAPIYEGEESHSVQDYQEAHQHHQPPEPQP-----YYPPPPPGEH------------MHGRPPMHHRQEGELSNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILNG---FAFVEFEEAESAAKAIEEVHGKSFANQPLEVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARENSLETTFSSVN---TRDFDGTGALEFPSEEILVEALERLNNIEFRG---SVITVERDDNPPPIRRSNRGG---------------------------FRGRGGFRGGFRGG-------------------------FRGGFSRGGFGGPRGGFGGPRGGYGGYSRGGYG-GYSRGGYGGSRGGYD---------------SPRGGYDSP--------------------------RGGYSRGGYGGPRNDYGPPRGSYGGSRGG------YDGPRGDYGPPRDAYRTR---DAPRERSPTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: *. . : ::. .. : : : . :. : * * *. .: : * .. . * * : :: **:*. :. . .:*:: : * :. .. : ..:** . .. *::::..... .: :.:: .: . .. * . *. . : . . .: .* . :. .:. * . . * *:. . . : . . . : . * :*. . . . . . *... ", "identical_positions": 24, "similar_positions": 107, "identity": "4.41%" }, { "cls_id": "homologset.agr.FB:FBgn0004595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A8R7-1", "uniprot_id": "A0A8I6A8R7_RAT", "id": "A0A8I6A8R7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMPFPGATIISQLLKN----------------NMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFG-RPTMSQFDVDRLCDEHLR------------------------------------------------------AKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKR---------------KQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQVYDSTDSE--------------------------------------------NDEDGDLSEDSMRSEILDARAQDSVGRSDNEMC---------------------------------------------------------------------------------------ELDPGQFIDRARALIREQEMAENKPKREGSNKERDHGPNSLQPEGK----------------------------------------------------HLAETLKQELNTAMSQVVDTVVKVFSAKP-----------------SRQVPQVFPPLQ--IPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGNVQMPSSTDQT--EALPLVVRKNSSEQSASGPATGGHHQPLHQS-----------------------------FRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSH---------HPCSPAHPPSTAEGLSLSLIKSECGDLQDMSDISPYS---------------------------GSAISFYLSPQE------------------------------------------------------------------------------------------------------QVLTKARRRSAQSRLP----------------CITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48437-1", "uniprot_id": "PROX1_MOUSE", "id": "P48437-1", "name": "Prospero homeobox protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKN----------------NMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFG-RPTMSQFDVDRLCDEHLR------------------------------------------------------AKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKR---------------KQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQVYDSTDSE--------------------------------------------NDEDGDLSEDSMRSEILDARAQDSVGRSDNEMC---------------------------------------------------------------------------------------ELDPGQFIDRARALIREQEMAENKPKREGSNKERDHGPNSLQPEGK----------------------------------------------------HLAETLKQELNTAMSQVVDTVVKVFSAKP-----------------SRQVPQVFPPLQ--IPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGSVQMPSSTDQT--EALPLVVRKNSSEQSASGPATGGHHQPLHQSPLS-----------------ATAGFTTPSFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSH---------HPCSPAHPPSTAEGLSLSLIKSECGDLQDMSDISPYS---------------------------GSAMQEGLSPN--------------------------------------------------------------------------------------------------------HLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92786-1", "uniprot_id": "PROX1_HUMAN", "id": "Q92786-1", "name": "Prospero homeobox protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKN----------------NMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFG-RPTMSQFDMDRLCDEHLR------------------------------------------------------AKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKR---------------KQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQIYDSTDSE--------------------------------------------NDEDGNLSEDSMRSEILDARAQDSVGRSDNEMC---------------------------------------------------------------------------------------ELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGK----------------------------------------------------HLAETLKQELNTAMSQVVDTVVKVFSAKP-----------------SRQVPQVFPPLQ--IPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGNVQMASSTDQT--EALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLS-----------------ATTGFTTSTFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSH---------HPCSPAHPPSTAEGLSLSLIKSECGDLQDMSEISPYS---------------------------GSAMQEGLSPN--------------------------------------------------------------------------------------------------------HLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHL7-1", "uniprot_id": "D3ZHL7_RAT", "id": "D3ZHL7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPP-AVLLSPQSQTCTHLAET-CMGQERSPPTAEVGSDSFFPSGQLPSSSLTDADWFWDEHIQ------------------------------------------------------AKRARVETIVRGMCLSPSSLVSGRARE------SSRCPEKVRERKR---------------KQSLPMHQG--PLKSSPAWDRGPKKGGTRVKEQLHLLKQQLRHLQEHVLQATEPRAPA--------------------------------------------QSPGGTES-----RSSLGAKARNTFPYS------------------------------------------------------------------------------------------------AWAVESKPHQSSSKDIGGAVKPGAAEVLQQSEEPVFCPSGPR----------------------------------------------------ALVETLRKELSRAVSQAVDSVLQQVLLDP-----------------QSLLPRQDGSCQGLASEGRSQPSPPGRSAYKDPLALATLPRKVQPQAGVPLGNSTLARPLDSPICPVSPRGVPRSYQSPLSNCPLTTVPSHIWENQ-------------------------------ILSQLLG-RGPDGHWSGSPSQDASHQSHTSPESAQQPWG--------LSQQRLP---------LSFTPVHLESRPL--LPAAVKMEQSALQGVADSLPFS---------------------------SVHIQEGLSPG--------------------------------------------------------------------------------------------------------HLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQAVSDGVTNAQALAVLRDSELFRVLNTHYNKGNDFEVPECFLQIATLTLQEFFRAVSTGKDSDPSWKKPIYKIISKLDSDIPEILKSSSYSQGLFPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BII1-1", "uniprot_id": "PROX2_MOUSE", "id": "Q8BII1-1", "name": "Prospero homeobox protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPPAAVLLPPQSRTCTHLAEETCMDQERSPATAEAGRDS-FPSGQLPSSSLTEADWFWDEHIQ------------------------------------------------------AKRARVETIVRGMCLSPSSSVSGRARE------SLRCPEKGRERKR---------------KQSLPMHQG--PLKSSPAWERGPKKGGTRVKEQLHLLKQQLRHLQEHVLQATEPRAPA--------------------------------------------QSPGGTEP-----RSSPRARPRNSCSSG------------------------------------------------------------------------------------------------AWTVENEPHQSSSKDLCGAVKPGAAEVLQYSEEPMLCPSGPR----------------------------------------------------ALVETLRKELSRAVSQAVDSVLQQVLFDP-----------------QRHLTQQERSCQGLASEGRNQPSPPGRSAYKDPLALATLPRKIQPQAGVPLGNSTLARPLDSPMCPVSPRGVPRSYQSPLPNCPLTNVPSHTWENQ-------------------------------MLRQLLG-RGPDGQWSGSPPQDAAFQSHTSPESAQQPWG--------LSQQQLP---------LSLTPVHLESRP---LPPPVKMEQGVLRGVADSLPFS---------------------------SIHIQEGLSPG--------------------------------------------------------------------------------------------------------HLKKAKLMFFFTRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQALSDGITNAQALAVLRDSELFRVLNTHYNKGNDFEVPDCFLEIAALTLKEFFRAVLAGKDSDPSWKKPIYKVISKLDSDVPEMLKSPSFLPGLFPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B8N5-1", "uniprot_id": "PROX2_HUMAN", "id": "Q3B8N5-1", "name": "Prospero homeobox protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPN-SILLSPQPQICSHLAEA-CTEGERSSSPPELDRDSPFPWSQVPSSSPTDPEWFGDEHIQ------------------------------------------------------AKRARVETIVRGMCLSPNPLVPGNAQAG----VSPRCPKKARERKR---------------KQNLPTPQG--LLMPAPAWDQGNRKGGPRVREQLHLLKQQLRHLQEHILQAAKPRDTA--------------------------------------------QGPGGCGTG----KGPLSAKQGNGCGPR------------------------------------------------------------------------------------------------PWVVDGDHQQGTSKDLSGAEKH------QESEKPSFLPSGAP----------------------------------------------------ASLEILRKELTRAVSQAVDSVLQKVLLDP-----------------PGHLTQLGRSFQGQVAEGRSEPSPPVGGACKDPLALAALPRRVQLQAGVPVGNLSLAKRLDSPRYPIPPRMTPKPCQDPPANFPLT-APSHIQENQ-------------------------------ILSQLLGHRYNNGHWSSSPPQDSSSQRHPSSEPALRPWRTTKPQPLVLSQQQCP---------LPFTSAHLESLP---LLPSVKMEQRGLHAVMEALPFS---------------------------LLHIQEGLNPG--------------------------------------------------------------------------------------------------------HLKKAKLMFFFTRYPSSNLLKVYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKSARQAISDGVTNPKMLVVLRNSELFQALNMHYNKGNDFEVPDCFLEIASLTLQEFFRAVSAGRDSDPSWKKPIYKIISKLDSDIPEIFKSSSYPQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29617-1", "uniprot_id": "PROS_DROME", "id": "P29617-1", "name": "Homeobox protein prospero", "aln": "MMSSEEYEADCFGLYSDENNVLLKANEPETTAATKQQHQPQFQQQQQQQQQQQQHHHQHQQPPPSSNGHTSPIPSQVNGDGSAANCGESGKTNTNTGSHSHSNSGNTNTDADKEQEREKAKEKANEEESEDSDDDVVVVLEGCEGNASSSSSSSNSNSNASSNNHKAAATTTTTATTANHCNRSGGSSRSHRSARSSRQISQSTAVGKTTTCAAKKPTAAQATTTTAKNSNSNSNVNVNVNVNSNGSGNGNANSKVNRRSRQRSLSKDINNQPASSNSNSNSSNNSSNSNGGATATAAGFMSSAAAAAAGAAGGGALFQPQSVSTANSSSSNNNNSSTPAALATHSPTSNSPVSGASSASSLLTAAFGNLFGGSSAKMLNELFGRQMKQAQDATSGLPQSLDNAMLAAAMETATSAELLIGSLNSTSKLLQQQHNNNSIAPANSTPMSNGTNASISPGSAHSSSHSHQGVSPKGSRRVSACSDRSLEAAAADVAGGSPPRAASVSSLNGGASSGEQHQSQLQHDLVAHHMLRNILQGKKELMQLDQELRTAMQQQQQQLQEKEQLHSKLNNNNNNNIAATANNNNNTTMESINLIDDSEMADIKIKSEPQTAPQPQQSPHGSSHSSRSGSGSGSHSSMASDGSLRRKSSDSLDSHGAQDDAQDEEDAAPTGQRSESRAPEEPQLPTKKESVDDMLDEVELLGLHSRGSDMDSLASPSHSDMMLLDKDDVLDEDDDDDCVEQKTSGSGCLKKPGMDLKRARVENIVSGMRCSPSSGLAQAGQLQVNGCKKRKLYQPQQHAMERYVAAAAGLNFGLNLQSMMLDQEDSESNELESPQIQQKRVEKNALKSQLRSMQEQLAEMQQKYVQLCSRMEQESECQELDQDQDVEQEQEPDNGSSDHIELSPSPTLTGDGDVSPNHKEETGQERPGSSSPSPSPLKPKTSLGESSDSGANMLSQMMSKMMSGKLHNPLVGVGHPALPQGFPPLLQHMGDMSHAAAMYQQFFFEQEARMAKEAAEQQQQQQQQQQQQQQQQQQEQQRRFEQEQQEQQRRKEEQQQQIQRQQQHLQQLQQQQMEQQHVATAAPRPQMHHPAPARLPTRMGGAAGHTALKSELSEKFQMLRANNNSSMMRMSGTDLEGLADVLKSEITTSLSALVDTIVTRFVHQRRLFSKQADSVTAAAEQLNKDLLLASQILDRKSPRTKVADRPQNGPTPATQSAAAMFQAPKTPQGMNPVAAAALYNSMTGPFCLPPDQQQQQQTAQQQQSAQQQQQSSQQTQQQLEQNEALSLVVTPKKKRHKVTDTRITPRTVSRILAQDGVVPPTGGPPSTPQQQQQQQQQQQQQQQQQQQQASNGGNSNATPAQSPTRSSGGAAYHPQPPPPPPPMMPVSLPTSVAIPNPSLHESKVFSPYSPFFNPHAAAGQATAAQLHQHHQQHHPHHQSMQLSSSPPGSLGALMDSRDSPPLPHPPSMLHPALLAAAHHGGSPDYKTCLRAVMDAQDRQSECNSADMQFDGMAPTISFYKQMQLKTEHQESLMAKHCESLTPLHSSTLTPMHLRKAKLMFFWVRYPSSAVLKMYFPDIKFNKNNTAQLVKWFSNFREFYYIQMEKYARQAVTEGIKTPDDLLIAGDSELYRVLNLHYNRNNHIEVPQNFRFVVESTLREFFRAIQGGKDTEQSWKKSIYKIISRMDDPVPEYFKSPNFLEQLE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . : .. : .. : . *: . : : : .: ******.*: ** **. : . . : :. . :. : : .. . : ::.**. :::** .:*:: * . : * : : .::: : . . : *:.*:. ::* **::: . . : : .. : : : ... : . : . . : .:. .:* . : : . : : . .. . . : *: *:* :. .* * **: * * *:*::**************** ****:.:*:.... * : :.**::.** ***: *.:***: * :. **:***.*: *:* : ****.***:*.::*. :** :**.. ", "identical_positions": 92, "similar_positions": 146, "identity": "5.4%" }, { "cls_id": "homologset.agr.FB:FBgn0004597", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62447-1", "uniprot_id": "CCNC_MOUSE", "id": "Q62447-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39947-1", "uniprot_id": "CCNC_RAT", "id": "P39947-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDK-----ERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTSLIAATTSVLKTRFSYASPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24863-1", "uniprot_id": "CCNC_HUMAN", "id": "P24863-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSE----------------------------------EEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLA-------WRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDA---------------------------RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25008-1", "uniprot_id": "CCNC_DROME", "id": "P25008-1", "name": "Cyclin-C", "aln": "MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNE----------------------------------DEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLS-------WRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKDAT--------------------------KQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPKPPPQR-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47821-1", "uniprot_id": "SSN8_YEAST", "id": "P47821-1", "name": "RNA polymerase II holoenzyme cyclin-like subunit", "aln": "MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEART---------LWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.** *:: :* * ***: : :: :: *: :* **.:*::** .:*** :*:.** : *::.*: ::..**: **.**** .: : .: :* .:: * ****** ::. ***::**:.* * ** : * :.*: * ::**: .*: *****. **:*** :: : * : .:::** **:::: : :: :.**: *..:.*: : : :* .. ", "identical_positions": 76, "similar_positions": 88, "identity": "21.65%" }, { "cls_id": "homologset.agr.FB:FBgn0004598", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63415-1", "uniprot_id": "PCSK6_RAT", "id": "Q63415-1", "name": "Proprotein convertase subtilisin/kexin type 6", "aln": "--------------------------------MPPRAPPAPGPRPPPR------------------AAGRHGLSPLAPRPWR-------------------WLLLLALPAVCSALPPP---------------------------------------------------------------------------------------------------------------------RPVYTNHWAVQVLGGPGAADRVAAAHGYLNLGQIGNLDDYYHFYHSKTFK--RSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR----------------------------------------------QARSD--SLYFNDPIWSNMWYMHCADKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAF-YERKIVTTDLR------QRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLK-ASDWKVNGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHMCVATADKRPRSIP--VVQVLRTTALTNACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTNWEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHPYRTFSSHQSRSRMLELSVPEQEPLKAEGPPPQAETPEEEEEYTG-------------VCHPECGDKGCDG-PSADQCLNCVHFSLGNSKTNRKCVSECPLGYFGDTAARRCRRCHKGCETCTGRSPTQCLSCRRGFYHHQETNTCVTLCPAGLYADESQRLCLRC-HPSCQKCVDEPEKSTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCRTCVGPSREECIHCAKS--FHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCEG-SSRNCSRCKAGFTQLGTSCITNHTCSN----ADETFCEMVKS------------------NRLCERKLFIQFC-----------------CRTCLLAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6XJP7-1", "uniprot_id": "F6XJP7_MOUSE", "id": "F6XJP7-1", "name": "Proprotein convertase subtilisin/kexin type 6", "aln": "--------------------------------MPPRAPPAPGPRPPPRAADV---------ARGAGAAGRHGLPPLALRPWR-------------------WLLLLALPAACSALPPP---------------------------------------------------------------------------------------------------------------------RPVYTNHWAVQVLGGPGAADRVAAAHGYLNLGQIGNLDDYYHFYHSKTFK--RSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR----------------------------------------------QARSD--SLYFNDPIWSNMWYMHCTDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAF-YERKIVTTDLR------QRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLK-ASDWKVNGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHVCVATADKRPRSIP--IVQVLRTTALTNACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTNWEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHPYRTFSSHQSRSRMLELSVPEQEPPKAAGQPPQAETPEDEEEYTAPSIQGSPNTLQTSVCHPECGDKGCDG-PNADQCLNCVHFSLGNSKTNRKCVSECPLGYFGDAAARRCRRCHKGCETCTGRSPAQCLSCRRGFYHHQETNTCVTLCPAGLYADESQRLCLRC-HPSCQKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELVKCGECHHTCRTCVGPSREECIHCAKS--FHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCEENCLSCEG-SSRNCSRCKAGFTQLGTSCITNHTCSN----ADETFCEMVKS------------------NRLCERKLFIQFC-----------------CRTCLLAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29122-1", "uniprot_id": "PCSK6_HUMAN", "id": "P29122-1", "name": "Proprotein convertase subtilisin/kexin type 6", "aln": "--------------------------------MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWR-------------------WLLLLALPAACSAPPP----------------------------------------------------------------------------------------------------------------------RPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFK--RSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR----------------------------------------------QVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAF-YERKIVTTDLR------QRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLK-ASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIP--LVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLELSAPELEPPKAALSPSQVEVPEDEEDYTAQSTPGSANILQTSVCHPECGDKGCDG-PNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKC-HPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKN--FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRCKTGFTQLGTSCITNHTCSN----ADETFCEMVKS------------------NRLCERKLFIQFC-----------------CRTCLLAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04592-1", "uniprot_id": "PCSK5_MOUSE", "id": "Q04592-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "------------------------------------------------------------------MDWDWGNRCSRPGRRD-------------------LLCVLALLAGCLLPVCR---------------------------------------------------------------------------------------------------------------------TRVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDYYHFYHSRTIK--RSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRD---------------------------------------------YDLSHAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIR--PNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYG------------AEDYAG-------------PCDPECSEVGCDG-PGPDHCSDCLHYYYKLKNNTRICVSSCPPGHYHADKKR-CRKCAPNCESCFGSHGNQCLSCKYGYFLNEETSSCVTQCPDGSYEDIKKNVCGKC-SENCKACIG-FHNCTECKGGLSLQGSRCSVTCEDGQFFNGHD--CQPCHRFCATCSGAGADGCINCTEG--YVMEEGRCVQSCSVSYYLDHSSEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGTCQMGAICKDGEYIDDQGHCQTCEASCAKCWGPTQEDCISCPVTRVLDDGRCVMNCPSWKFEFKKQCHPCHYTCQGCQGSGPSNCTSCRADKHGQERFLYHGECLENCPVGHYPAKGHACLPCPDNCELCYNPHVCSRCMSGYVIIPPNHTCQKLECRQGEFQDSEYEECMPCEEGCLGCTEDDPGACTSCATGYYMFERHCYKACPEKTF--GVKWECRACGTNCGSCDQHECYWCEEGFFLSGGSCVQDCGPGFHGDQELGECKPCHRACENCTGSGYNQCSSCQEGLQLWHGTCLWSTWPQVEGKDWNEAVPTEKPSLVRSLLQDRRKWKVQIKRDATSQNQPCHSSCKTCNG---SLCASCPTGMYLWLQACVPSCPQGTWPSVTSGSCEKCSEDCVSCSGADLCQQCLSQPDNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCEGNATSCNSCEGDFVLDHGVCWKTCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHRSCPKSFYPDMRQ--CVPCHKNCLECNGPKEDDCKVCADTSKALHNGLCLDECPEGTYKEEENDECRDCPESCLICS--SAWTCLACREGFTV-VHDVCTAPKECAAVEYWDEGSHRCQPCHKKCSRCSGPSEDQCYTCPRETFLLNTTCVKECPEGYHTDKDSQQCVLCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKSCRGPRPTDCQSCDTFFFLLRSKGQCHRACPEHYYADQHAQTCERCHPTCDKCSGKEAWSCLSCVWSYHLLKGICIPECIVGEYREGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLDMDDNRCLHCCN----ASHSRRSQDCCDCQSSTDECILPAR-EAEFYEHT----KTALLVTSGAMLLLLLGAAAVVWRKSRS------RPVAKGRYEKLAE-------------PTVSYSSYRSSY-----LDEDQVIEYRDR-----DYDEDDED-DIVYMGQDGTVYRKFKYGLLDETEDDELEYDDESYSYQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41413-1", "uniprot_id": "PCSK5_RAT", "id": "P41413-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "------------------------------------------------------------------MDWGWGSRCCRPGRRD-------------------LLCVLALLAGCLLPVCR---------------------------------------------------------------------------------------------------------------------TRVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDYYHFYHSRTIK--RSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRD---------------------------------------------YDLSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIR--PNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYG------------AEDYAG-------------PCDPECSEVGCDG-PGPDHCTDCLHYHYKLKNNTRICVSSCPPGHFHADKKR-CRKCAPNCESCFGSHADQCLSCKYGYFLNEETSSCVAQCPEGSYQDIKKNICGKC-SENCKTCTG-FHNCTECKGGLSLQGSRCSVTCEDGQFFSGHD--CQPCHRFCATCAGAGADGCINCTEG--YVMEEGRCVQSCSVSYYLDHSLEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGMCQMGAICKDGEYIDEQGHCQICDASCAKCWGPTQDDCISCPITRVFDDGRCVMNCPSWKFELKKQCHPCHHTCQGCQGSGPSNCTSCKA---------------------------------------------------------------------GEFQDSEYGECMPCEEGCVGCTVDDPGACTSCATGYYMFERHCYKACPEKTF--GEKWECKACGTNCGSCDQHECYWCEEGFFLSSGSCVQDCDPGFYGDQELGECKPCHRACETCTGLGYNQCSSCPEGLQLWHGTCIWPTWPHVEGKVWNEAVPTEKPSLVRSLPQDRRKWKVQIKRDATRQYQPCHSSCKTCNG---SLCTSCPAGTYLWLQACVPSCPQGTWLSVRSSSCEKCAEGCASCSGDDLCQRCLSQPSNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCKGNATSCHSCEGDFVLDHGVCWETCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHHSCPKNFYPDMRQ--CVPCHKNCLGCNGPKEDDCKACADTSKVLHNGLCLDECPKGTYKDEVNDECRDCPESCLICS--SAWTCLTCREGFTV-VQDVCTAPKECAAIEYWDVGSHRCQPCHRKCSRCSGPSENQCYTCPRETFLLNTTCVKECPEGYHTDKDSHQCVPCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKTCRGPQPTDCQSCDTFFFLLRSKGQCHLACPEHYYADQHAQTCERCHPTCDKCSGKEAWNCLSCVWSYHLLKGICTPECIVGEYRDGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLQMDDSRCLRCCN----ASHPHRSQDCCDCQSSTDECILPASDDTVFHEHT----KTALLVTSGAMLLLLLGAAVVVWRKSRS------QPVAKGRYEKLAE-------------PTVSYSSYRSSY-----LDEDQVIEYRDR-----DYDEDDED-DIVYMGQDGTVYRKFKYGLLDEAEDDELEYDDESYSYQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92824-1", "uniprot_id": "PCSK5_HUMAN", "id": "Q92824-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "--------------------------------------------------------------------MGWGSRCCCPGRLD-------------------LLCVLALLGGCLLPVCR---------------------------------------------------------------------------------------------------------------------TRVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIK--RSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRD---------------------------------------------YDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIR--PNSAVRSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYG------------TEDYAG-------------PCDPECSEVGCDG-PGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKR-CRKCAPNCESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKC-SENCKTCTE-FHNCTECRDGLSLQGSRCSVSCEDGRYFNGQD--CQPCHRFCATCAGAGADGCINCTEG--YFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDGEYVDEHGHCQTCEASCAKCQGPTQEDCTTCPMTRIFDDGRCVSNCPSWKFEFENQCHPCHHTCQRCQGSGPTHCTSCGADNYGREHFLYQGECGDSCPEGHYATEGNTCLPCPDNCELCHSVHVCTRCMKGYFIAPTNHTCQKLECGQGEVQDPDYEECVPCEEGCLGCSLDDPGTCTSCAMGYYRFDHHCYKTCPEKTY--SEEVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWN---------------------------DILRKLQPCHSSCKTCNGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH--CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCS--SSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCN----TSDPPSAQECCDCQDTTDECILRTSKVRPATEHF----KTALFITSSMMLVLLLGAAVVVWKKSRGR----VQPAAKAGYEKLAD-------------PNKSYSSYKSSYRESTSFEEDQVIEYRDR-----DYDEDDDD-DIVYMGQDGTVYRKFKYGLLDDDDIDELEYDDESYSYYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4U3-1", "uniprot_id": "A0A8M9Q4U3_DANRE", "id": "A0A8M9Q4U3-1", "name": "", "aln": "------------------------------------------------------------------------------MTST-------------------IFFPYALFFGIGLQCVQ---------------------------------------------------------------------------------------------------------------------MRLYTNRWAVKITGGPEAADLIAEKYGFVNMGQIGGLVDHYQFQHSGIIK--RSTIKSKGNHSLITMETKVEWIQQQMVQKRVKRT---------------------------------------------ETMDQTHDGSFNDPKWDSMWYIHCDHN---CLTDMNIQAAWRRGYTGKGVVVSILDDGIERQHPDLKQNYDARASYDVNGNDPDPTPRYDVTNENKHGTRCAGVVAASANNSLCIVGIAYNAKIGGVRMLDGDMTDMVEAQSLNLRQQYIDIYSSSWGPDDDGRTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQSQDHCSCDGYTNSIYTISVGSTTQSGRKPWYLEECSSTLATTYSSGDS-HSPGVVTTDLR------QRCTDEHSGTSASAPMAAGIIALTLEANPALTWRDIQHIIVKTSSRGHLS-ASDWQSNGAGYDVSHLYGFGLLNAEAMVKNAETWKQVPSQHICEENIGQNARIIS--PERVLRSVLKSSGCSAQRLQRVVYLEHVIVRVTITHPHRGDLSITLTSPSGTTSQLLANRPNDHSSEGFIKWEFMTTHCWGERLAGDWILDIRDTPSPQRNNRLQGKLVEWSLVLYGTSTHPYIR-HEQPRSAQL-------PSEDEI------------TEEYNG-------------SCDPECSEDGCEG-PGPHQCVSCLNLFLKFKNNTRTCVSECPSG-YWGDKKR-CKKCYSSCKSCLGSRSDQCTACKSGYHLNEEKNNCVTSCEDGYFLYHEENLCRKCNIENCMKCTS-ASICTECSEGTSLVGNRCQKSCEVGSYYSEPEDSCEACHPACATCAAAGLESCNRCAEG--YLMENWRCVSSCSQGFYAEQQNSDNQSTCKRCDASCLACVGPTKTNCSECVDGHSLQDGVCVLSHNCGDGEYQDESGECQSCHVSCQKCKGPQSEDCLSCFITHLLDYGQCVVSCSNGKYPSGGQCHLCDHTCAQCVDAGPSNCTSCDTDKFGVDRYLYHGECVDACPKAHFHTVLKACEPCPSYCKLCSSATHCIKCEDSFYVN--NGVCNKLECGEGEVEDPEYDDCMPCEEGCHKCVLYNPKHCLSCINGYYRFEESCYKNCPSKTYPVEETMSCVSCEHDCVNCDEDECSWCEADFFISNGKCVRECPDGFYNDDESQECEECHSDCKTCSGPEDSDCESCSEGLTLDNGACVSEQDVCPAQMYLTD----------------------------DGECEACHPLCESCWGKMKNQCNTCVKGRYLNADQCVARCPVGSFGSKDSGHCETCPQGCAQCQDEQLCTRCQSTRKNPLYLQAGQCVRKCTRG-YPVGQVCKSCASACTSCEKNATHCMSCEGTLLLYKHECVSSCPSAHTVSNGECVQCQENCAICS-EDGCTGCKEDYFLHVGQCIAVCPDGFFEDMNQGICKRCHVDCSLCDGPESNNCDACSDSDSTLHYGACLTPCSSHTYRESRSGECIDCDSSCLTCSGPHDTSCTSCSEGLKMDAHGRCATPTTCPSHHYSNQDGE-CHLCHKYCHECSGPHQDQCLSCNQKHYLLNGSCVNNCPDEYFSG-ETQRCEPCHPNCLTCMGRHSHECLSCRDHLYRDVKECVDTCRSGYYASAVSSTCERCDESCGECLQAGAEGCVSCRQGMLFIRKQGRCVSSCPESYYHDTHHKTCEACHPSCRTCIGKSVEDCDTCYPGFTLTGGVCESPCITGEYAKSEEQDYNCESCDESCLECKGPGPHNCTICPAQFILASE-GRCLPCCTNTELEDAATVQQECCNCTENRGECVLSTNFAFRNHEEEDYTGNLPLFITTSILLVFVLIAVIMLIKRSLSKRALPDTPVPRG-YEKLGHDGGRDSFYRGTSSATSAYSGQASSS--SGHFRESKLVDLGDQKGSRDDDDEDDEDEDIVYMGQDGTVYRKFKYGQLGDEQEDELEYDDESYNYR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30432-1", "uniprot_id": "FUR2_DROME", "id": "P30432-1", "name": "Furin-like protease 2", "aln": "MSNTTRSSRVTIGRIGTTPQITDPWSSGLEKQRPSRCGGPKSLAEPTYRKIGRRKMMLHMRVHDPGTTVTQRAKETATAKLNRIYLCTFNRMAQSCIYFVLFLVILSPNTSCALRSSAGETQNYVGILSNDSATTTYDVSSLHSSRRTNPPSSSSSSSSNVDVDYRNDRELHKVDLVGLGGERAGQAETISGGKYDYNYENTHTNASAKDEIVERQSNSLDFDGVDMFGAFSIPEEAIYTNEFAVNIPAGKQMADVIATKHGFINRGQIGSLDNYYLFQHHHVSK--RSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFPDPLFKEQWYLNGGAKDG---LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQDNG--DNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSRPAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTIN-EVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVINGGR--RRVNQPGILSKWQLIFYGTSTQPMRLKSELLNSSPQLRS----PSSSNP-------------------------------FLFPSASNIGQPANEGGNFNTDSFASYLNYQNIFSSAGSDPEPATATLDGQN-----------VTAAIAGGSSAESLGFTASAAQLVAAPETRDG-DKKILHSCDAECDSSGCYGRGP--TQCVACSH--YRLDNTCVSRCPPRSFPNQVG-ICWPCHDTCETCAGAGPDSCLTCAPAHLHVIDLAVCLQFCPDGYFENSRN----RTCVPCEPNCASCQD-HPEYCTSCDHHLVMHEHKCYS--ACPLDTYETEDNKCAFCHSTCATCNGPTDQDCITCRSSRYAWQNKCLISCP-----------------------------------------------------------------------------------------------------DGFYADKKRLECMPCQEGCKTCTSN--GVCSECLQNWTLNKRD----------------KCIVSGS-------------------------EGCSESEFYSQVEGQCRPCHASCGSCNGPADTSCTSCPP-------------------------------------------------------------------------------NRLLEQSRCVSGCREG-FFVEAGSLCSPCLHTCSQCVSRTNCSNCSKG----LELQNGECRTTCADGYYSDRGICAKCYLSCHTCSGPRR--------------------------------------------NQCVQCPAGWQLAAGECHPECPEGFYKSDFG--CQKCHHYCKTCNDAGPLACTSCPPHS--MLDGGLCMECLSSQYYDTTSATCKTCHDSCRSCFGPGQFSCKGCVP--------------------------------------------------PLHLDQLNSQCVSCCQN------QTLAEKTSSAACCNCDG-ETGECKATSTGGKRRTVVGSGSAYKSSESKHGSFENDGNAREFVLRLDSPLTAITAIAVAICLLIITIFSIIFAVLQRNSNHVSRNSVRYRKIANTSSGRRKNLSAKPTSDARFIFNIGEDDDTDGDNSDDELDG-NVGTDINNRIVYDRKGNDHG---HEFYIESTNDIDAIEFHCNGAGAQKAETQLQRCNANGDDDDILHYDRHTNAERKNHPSSTTSRTNIRS--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13134-1", "uniprot_id": "KEX2_YEAST", "id": "P13134-1", "name": "Kexin", "aln": "------------------------------------------------------------------------MKVRKYITLC-------------------FWWAFSTSALVSSQQIP---------------------------------------------------------------------------------------------------------------------LKDHTSRQYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAP------------------------------------PMDSSLLPVKEAEDKLSINDPLFERQWHLVNPSFPG---SDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKP---RLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSG---EYIHSSDIN------GRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTN--STEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENGHRIDFHS-----WRLKLFGESIDSSKTETFVFG----------------------------------------------------------------------------NDKEEVEPAATESTVSQYSASSTS------------ISISATSTSSISIGVETSAIPQTTTASTDPDSDPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDTDSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKLQELQPDVPPSSGRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.. . : .. : .: :: * ::* * : ** .. . . : :: * . : ** : *:: ::*: * .. ** .:*.:*:***:: : ** *: . .* *.*.* * * :: ******* :** *. * **:.:**.*.*:*:*.*.:. ** :: . .***.**** *** ::**. *.: *: *: ** . *:::*:****** * *. *******:::::.: . . :* * * *::.:*.***** : : *: *: * ***.:**:.**: :* **** *****:*:: : :: . ..* .. . ** :*:* ::* :: :. * * * : . .. :*** : ** : * ** * * * * * ..* .* *:: ***. * * :.: * * * ::* : .. : . : . . : * .. . . . . : .. . . . . . ", "identical_positions": 150, "similar_positions": 165, "identity": "6.76%" }, { "cls_id": "homologset.agr.FB:FBgn0004606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62947-1", "uniprot_id": "ZEB1_RAT", "id": "Q62947-1", "name": "Zinc finger E-box-binding homeobox 1", "aln": "------------------------------------------------------------------------MADGPRCKRRKQANPRRNNVTNYNT--------VVEANSDSDDEDKLHIVEEESVT---DAADCEGGVPDDELP--TDQTVLPG-GSDRA----GSAKNCWQDD----------------------------------VKDDECDSDAEN---------EQNHDPNVEEFLQQQDTAVIYPEAPEEDQRQGTPEASGHDDN---------GTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFS-----CSLCSYTFAYRTQLERHMTSHKSGREQ-RHVTQSGGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLMPVNGRPRSGLKTSQCSSP-SLSTSPGSPTRPQIRQKIEN---KPLQEPLSVNQIKTEPVDY-EFKPIVVASG-INCSTPLQNGVFSGGGQLQATSSPQGVVQAVVLPTVGLVS---PISINLSDIQNVLKVAVDGNIIRQVLENNQ---ASLASKEQEAVSASSIQQG-GHSVISAISLPLVDQDGTTKIIINYSLEQPGQLQVVPQNLKKENPAPPKSCKSEKSPEDLTVKSEKDKSFDGAADES--TCLLCEDCPGDLNALPELKHYDP--------EHPAQPPP-PAPATEKPESS-----------ASSA-GNGDLSPSQPPLKNLLSLLKAYYALNAQPSTEELTKIADSVNLPLDVVKKWFEKMQAGQIP-------GQSLEPPSPGPGS-------GNIPAKTEEQPQPVDGNEPQEDSTRGQSPLKMTSSPVLP--------VGSAINGSRSCTSSPSPLNLSSARNPQGYSCVSEGTQ-EEPQVEPLDLSLPKQQG--------ELLERSTVSSVYQNSVYSVQE---EPLNLSCAKKEPQKDSCVTD-------SEPVVNVVPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYSA-TVSPAMQEPPVKVIQPNGNQDERQDTSSEGVS-VEDQNDSDCTPPKKKTRKAENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICRKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKRGAEDRDAMEQE--DTGPEALPEVLPTELVGARASPSQ--ADSDE-RESLTREEDEDSEKEEEEEDKEMEELQEDKECENPQEEEEEEEEEEEEEEEEEEE--EAEEAEHEAAAAKTGGAVEEE-AAQQAGSFQQKASGS------ESKRLSEEKTNEA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64318-1", "uniprot_id": "ZEB1_MOUSE", "id": "Q64318-1", "name": "Zinc finger E-box-binding homeobox 1", "aln": "------------------------------------------------------------------------MADGPRCKRRKQANPRRNNVTNYNT--------VVEANSDSDDEDKLHIVEEESIT---DAADCEGGMPDDELP--ADQTVLPG-GSDRG----GGAKNCWQDN----------------------------------VKDNECDSDAEN---------EQNHDPNVEEFLQQQDTAVIYPEAPEEDQRQGTPEASSHDEN---------GTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFS-----CSLCSYTFAYRTQLERHMTSHKSGREQ-RHVTQSGGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLMPVNGRPRSGLKTSQCSSP-SLSTSPGSPTRPQIRQKIEN---KPLQEPLSVNQIKTEPVDY-EFKPIVVASG-INCSTPLQNGVFSSGGQLQATSSPQGVVQAVVLPTVGLVS---PISINLSDIQNVLKVAVDGNVIRQVLETNQ---ASLASKEQEAVSASPIQQG-GHSVISAISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKKEIPAPTNSCKSEKLPEDLTVKSETDKSFEGARDDS--TCLLCEDCPGDLNALPELKHYDP--------ECPAQPPP-PAPATEKPESS-----------ASSA-GNGDLSPSQPPLKNLLSLLKAYYALNAQPSTEELSKIADSVNLPLDGVKKWFEKMQAGQIP-------GQSPDPPSPGTGS-------VNIPTKTDEQPQPADGNEPQEDSTRGQSPVKIRSSPVLP--------VGSAMNGSRSCTSSPSPLNLCSARNPQGYSCVAEGAQ-EEPQVEPLDLSLPKQQG--------ELLERSTVSSVYQNSVYSVQE---EPLNLSCAKKEPQKDSCVTD-------SEPVVNVVPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYSA-TVSPAVQEPPVKVIQPNGNQDERQDTSSEGVSTVEDQNDSDSTPPKKKTRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICRKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKRGAEDRDAMEQE--DAGPEVLPEVLATEHVGARASPSQ--ADSDE-RESLTREEDEDSEKEEEEEDKEMEELQEGKECENPQGEEEEEEEEEEEEEEEEEEEVEADEAEHEAAA-KTDGTVEVG-AAQQAGSLEQKASESEMESESESEQLSEEKTNEA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37275-1", "uniprot_id": "ZEB1_HUMAN", "id": "P37275-1", "name": "Zinc finger E-box-binding homeobox 1", "aln": "------------------------------------------------------------------------MADGPRCKRRKQANPRRNNVTNYNT--------VVETNSDSDDEDKLHIVEEESVT---DAADCEG-VPEDDLP--TDQTVLPGRSSERE----GNAKNCWEDDRKEGQEILGPEAQADE--------------AGCTVKDDECESDAEN---------EQNHDPNVEEFLQQQDTAVIFPEAPEEDQRQGTPEASGHDEN---------GTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFS-----CSLCSYTFAYRTQLERHMTSHKSGRDQ-RHVTQSGCNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLIPVNGRPRTGLKTSQCSSP-SLSASPGSPTRPQIRQKIEN---KPLQEQLSVNQIKTEPVDY-EFKPIVVASG-INCSTPLQNGVFTGGGPLQATSSPQGMVQAVVLPTVGLVS---PISINLSDIQNVLKVAVDGNVIRQVLENNQ---ANLASKEQETINASPIQQG-GHSVISAISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKKENPVATNSCKSEKLPEDLTVKSEKDKSFEGGVNDS--TCLLCDDCPGDINALPELKHYDL--------KQPTQPPPLPAAEAEKPESS-----------VSSATGDGNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQIS-------VQSSEPSSPEPGK-------VNIPAKNNDQPQSANANEPQDSTVNLQSPLKMTNSPVLP--------VGSTTNGSRSSTPSPSPLNLSSSRNTQGYLYTAEGAQ-EEPQVEPLDLSLPKQQG--------ELLERSTITSVYQNSVYSVQE---EPLNLSCAKKEPQKDSCVTD-------SEPVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYST-TVSPAVQEPPLKVIQPNGNQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEERDSTEQE--EAG----PEILSNEHVGARASPSQ--GDSDE-RESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEE------EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGES-------SEQVSEEKTNEA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5YC43-1", "uniprot_id": "A0A8I5YC43_RAT", "id": "A0A8I5YC43-1", "name": "Zinc finger E-box-binding homeobox 2", "aln": "-------------------------------------------------------------------MKQPIMADGPRCKRRKQANPRRKNVVNYDN--------VVDAGSETDEEDKLHIAEDDGIANPLDQETSPASMPNHESSPHMSQGLLP-REEEEDEIRESVVEHSWHSGEILQASVDGP------------------------VKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEEN-----DLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFS-----CPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRN--NIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHG-FSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGLEAPLLGFPTMNSNLSEVQKVLQIVDN-TVSRQKMDCKTEDISKLKGYHMKDPCSQPEEQGVTSPSIPAVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTD-DKMIENHSIPTPFSCQFCKESFPGPIPLHQHERYLC--------KMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGLTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSSSRSPSLERNSKPLAPNSNPTTKDSLLPRSPVKPMDSITSPSIAELHNSVTSCDPPLRLTKSSHFT-----NIKAVDKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMREPKSIIATKNKTKATSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDN-----KSTNPVFGMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDLTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKG-HLEPTELLMNRAYLQSITPQGYSDSEE-RESMPRD----GESEKEHEKEGEEGYGKLRRRDGDEEEEEEEEESENKSMDT-----DPETIRDEEE--TGDHSMDDS---SEDGKMETKSDHE------------EDNMEDGME", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0G7-1", "uniprot_id": "ZEB2_MOUSE", "id": "Q9R0G7-1", "name": "Zinc finger E-box-binding homeobox 2", "aln": "-------------------------------------------------------------------MKQPIMADGPRCKRRKQANPRRKNVVNYDN--------VVDAGSETDEEDKLHIAEDDSLANPLDQDTSPASMPNHESSPHMSQGLLP-REEEEEELRESVVEHSWHSGEILQASVAGPEEMKEDYDAMGPEATIQTTINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEEN-----DLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFS-----CPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRN--NIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHG-FSGSSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDN-TVSRQKMDCKTEDISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTD-DKMIENHSISTPFSCQFCKESFPGPIPLHQHERYLC--------KMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGLTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERTSKPLAPNSNPTTKDSLLPRSPVKPMDSITSPSIAELHNSVTSCDPPLRLTKSSHFT-----NIKAVDKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMREPKGIIATKNKTKATSINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDN-----KSNNPVFGMNPFSAKPLYTPLPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGDLLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKG-HLEPTELLMNRAYLQSITPQGYSDSEE-RESMPRD----GESEKEHEKEGEEGYGKLRRRDGDEEEEEEEEESENKSMDT-----DPETIRDEEE--TGDHSMDDS---SEDGKMETKSDHE------------EDNMEDGME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60315-1", "uniprot_id": "ZEB2_HUMAN", "id": "O60315-1", "name": "Zinc finger E-box-binding homeobox 2", "aln": "-------------------------------------------------------------------MKQPIMADGPRCKRRKQANPRRKNVVNYDN--------VVDTGSETDEEDKLHIAEDDGIANPLDQETSPASVPNHESSPHVSQALLP-REEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTMGPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEEN-----DLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFS-----CPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRN--NIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHG-FSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDN-TVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTD-DKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLC--------KMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFT-----NIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDN-----KSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKG-HLEPTELLMNRAYLQSITPQGYSDSEE-RESMPRD----GESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDT-----DPETIRDEEE--TGDHSMDDS---SEDGKMETKSDHE------------EDNMEDGM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GCP6-1", "uniprot_id": "A0AC58GCP6_DANRE", "id": "A0AC58GCP6-1", "name": "", "aln": "--------------------------MDINQSRADSINMTCHHIPDLRSWMKERSPCGLLPSDPLLSMKQEIMAEGPRCKRRKQANPRRKNVLSYEN--------VVDAGSGSDDEDRLLGSEG---------EGSPAGVPSLEASPRVAHALLSCRGDEENESQDGAGAHVWRHGELN-----GSEERKAEYNSMSPDISLHG-IGNGTVKGIDASSELESFFAKRKLDDGEGHAASIAEYLQ--DTVIIYPEDPEEGTRLGTPEANGQDENEN---DLALRTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNDESFP-----CPLCSDTFAYRTQLERHMATHKPARDQPQLLNEGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECSNCKKRFSHSGSYSSHISSKKCIGLISINGRVRHGVNNKPGSSPNSAASSPGSPALAQLRHKLENGRSMSLQDPSAHTDIKSEPMDFNEYRLMIASQQEYGASGAFLNGGGRGGSPPGMHSSSQNPLQHLGIGSDSHPLGYTGFINNMSEVQKVLQIVDN-TVCRQKMDGNPEEISKLRAY-MKELGSQMEEQNRVLASQQ--SFLGVGHNSPTKTIIDYTLEKVNEAKACLQSLTEDSKRRLMDIKKERPSHAMDLLSE-DKALERDAQYAPFSCQYCKETFSGPIPLHQHERYLC--------KMNEEIKAVLKPNDTVPTGRRGLFGSEQQAGVISSSLERNATSPVNPYKDHMSLLNVYFSMNTEPNSEELRKISMAVGLPQEFVKDAFVQWKAQSH---HSFSRKRSPPPERSGETNHVRDSAFARSPVS--LGQYGDSTAEIQ-AITNGDSGHKLSRTHQITGTRQTNEKPLDSVDHLRGETPSPLNLSSSSSKHSHSSSYTPNSLTSEDAHGEPLDLSLPKQVS------KAERRAKPNGFSIEHTSNSTAREPGTEPLNLAHIKKEFNGPNSLGNENQMDKSSSPIFSINPFGGGHMYTSLPPHGAFPPPTFMSTTQASIPGLRPYPGLDPMSFLPPMAYTYAAGAATFAEMQQRRKYQRKQGFQGDLLDSAGDYLSGLEDLTDSESLLARKKIKKTESGMYACDLCDKTFQKTSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAKQENHNNGGPLEPTELLMRRAYLQGLGPLGFSDPEDQAEDITRENTILRDGTESGARETEETYAEVTDRQETGLMGEEEMEGQRFDTRS-----PDGTAKDEKESEVTGGTEDES---SEEGKRNHDGENE------------DAD------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28166-1", "uniprot_id": "ZFH1_DROME", "id": "P28166-1", "name": "Zinc finger protein 1", "aln": "MLSCLAPSSSRFGQEDTIIQQSMPSTSPFAMQFPSLASTLLHHNQSPKHSNPGSSGIQDAHPNQPGAAADAFLVKCTQCHKRFPEYQSLSEHIASEHPHDKLNCGAAQPESDAEDEQSNMSGSSRRYAKSPLASNNNSSTANANNNSTSSQSMNNNSELAKNHNSANKMSPMCSPGSLTPGDLFAQLQHPPPQLPPHLHAQFMAAAASLAMQSARTASSPSQ---QQQQQLQQQQQLQQQQQHQMAMQQLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTASFASREQLEQHEQLHSPCGPAAVSNVSQTCRICHKAFANVYRLQRHMISHD----------ESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLE--------KSPGSASSASRRSPSDHGK-GKLPEQPSLPGLP-HPMSYFASDAQVQGGSAAPAPFPPFHPNYMNAALLAFPHNFMAAAAGLDPR------------VHPYSIQRLLQLSAAGQQQREEEREEQ------QKQQQHDEEETPDEPKLVMDIEEPETKEMAPTPEATEAATPIKREESREASPDPESYRSSSQAIKQEQEPLNVAEERQTPVEEHAPVEHAADLR---CSRCSKQFNHPTELVQHEKVLCGLIKEELEQHFQQQQATSFALASASEEDEEDEEMDVEEEPRQESGERKVRVRTAINEEQQQQLKQHYSLNARPSRDEFRMIAARLQLDPRVVQVWFQNNRSRERK-------------------------------------------------MQSFQNNQAAGAAPPMP------------IDSQASLTREDQPLDLSVKRDPLTPKSESSPPYIAPPSGEALNPEAINLSR-----------KFSTSASMSPASISPSSA---AALYFGAAPPPSPPNSQLDS---------------TPRSGQAFPGLPP-YMLPMSLPMEALFKMRPGGDFASNHALMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDEFGAGVLMPPKPRRGKAETHGHAGDPDLP------YVCDQCDKAFAKQSSLARHKYEHSGQRPYQCIECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. .:*::* .: : ..:. * :::*: . . .. : : : . . . ::. *. .. : : . : * :: *: * . *: .* . : . *.. :: .* * .: .*::* : : . .. * :* :** :*:*** :*. :.. *****.**.****:*******:********: * ** ********:***::*****.: .. * : ** ..: .. * :: : : . : .*:.: : . . : . . : : .:*.:*:: *: : . : . .*: . *: : . :. . . : . : . .: * *.. * : :: : : . . . : :: . *: ::::* .*. :*: *: : * *: * : : . : . :. : . * . *. :.. .. *.*: . : .. .: * . .* : . : . . . :*. . . * . : * .: : : . . . :.: . . ::. . *.** *** * * *** ******:*:**::* * ********* ** ********:**.** ********************* * ", "identical_positions": 166, "similar_positions": 221, "identity": "12.28%" }, { "cls_id": "homologset.agr.FB:FBgn0004607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LG51-1", "uniprot_id": "A0ABK0LG51_RAT", "id": "A0ABK0LG51-1", "name": "Zinc finger homeobox protein 4", "aln": "METCDSPPISRQENGQS-------TSKLCGTTQLDNEVP--EKVAGMEPD--------RENSSS--HDNLKTEEHERKSEVLLGFSIEN-----AAATQVTSAKEIPCN------------ECATSFPSLQKY-------------MEHHCPNARLP-VLKDD-ESETSELED--SDVENLTGEIVYQPDGSAYIIEDSKESGQN--AQTGANSKLFSTAMFLDSLASVGEKSDQSASGPVSFYPQIINTFHIASSLGKPFT-ADPAFPNTSALAGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVTDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQRLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTFRGLWSAFHVENGDSLPAGFAFLKGSASPSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPITSVSLSHSSSESSKMSESKDQENNCERP--KENTVLHPNGECPIKSEPNEPGDEDEEDAYSNELDDEEVG-ELTDSIGNK---------------------------------------DFPLLNQSISPLSSSVLKFIEKGTSSSSSGTSADD------AEKKTQAAAAAAAGR-------NSGNVTNSYGIGGKDFADGSVSRDGATAAHPSETTRGDEDSSMTSHQHGFTPS-------------------------TPGTPGPGGDGSPGNGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP-GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGN----GEQVFGHSAPAPNTSLSG----------------------------------------------CGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLA---------------------PAEAELYQYYLAQNIGLTG------TKLENP-ADPQLLINPFQLDSAT-AAALAPGLVNNELPPEIRLASGQLMGDDLSLLTAGELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVNSDRS----LPEEDWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGG--------KTNEWRLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQ------KQESAVNSES-CYYYCAVCDYSSKIKLNLVQHLRSVKHQQTEGLRKLQLHQQGLPPEEDNLSEIFFVKDCPANELETASLGARTGVDELTEQQLRTASEELSEDAGGALKPTTVTEDDEKETQERDNSEGKVSNNDPGVITPEKELKVAVAGATQPLLLAKEDDTGTKRSKPTEDNKFCPEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPATTPEKSERDPP---TAMAAAGSGKYSGDSPVDDKSMSGLEDSKVGVEIK--NEEQKPAKEPIETSEWSKNSSRDANISDALQDQLSEQQ-KRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQHLYASLPMNGELWAEGETMPQEDHGLEQEM-ERE-YEVDHEGKASPVGSDSSSIPDDLGSEPKR-TLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVP-----QEANSSTDNKPYKCSICSVAYSQSSTLEIHMRSVLHQTKARAAKLEPSRHLS-----SGHSITAAVNS---------------------------------PGQGMLESMSLAPVNS-----KDTHLDAKELNKKQTPEIITAQPT-----------------HHPPPRSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQP-QFLFPFYIPGAEFSLGPDLALPSSTTFGMPGMTTGMAGSLLEDLKQQIQTQHHVGQTQLQLLQQQAQQYQAAQPQLQPPNQQP-PPPPQQQPQQPPSKLLKQEQGSLANTDCQLMKDAPSYKEAEEMTEKEE-KPKQESTNDTDGLKDSKDVKKQKSLEPCIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKS---------------GEGENSEKLECGTCGKLFSNVLILKSHQEHVHGQFFPYGALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSALGPVKIPNTVSAPLQAPPPTPPPPPPPPPPPPPPPPPPP-SAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDT-LSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAEA-KDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVLYKPCTVSGQTDTAKSTAAPVAS----SGSGTSTPLIPSPKPEPEKNSPKPEYPAEKTKQNDPSLP-QGIKSAPSSVSTSSEPQQA----------------------SISQPPPQL--PKQPQLIGRPPSASQTPIPSSPLQISMTSIQNSLPPQLLQYPCDQCTIAFPTLELWKEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASTAHTTAPASVAASLKRKLDDKEDNNCSEKEGG--NSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSENELASTVSTPVSKTAELSPKNLLSPSSFKAECPEDVENLNAPSADAGYDQNKTDFDETSSINTAISDATTGDEGAADMEN-TGGSEEVKPALSPKETKSLDSLPKAGTTPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSK--SSDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKIN---IGKPFMINQSGTDGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQ----QPGITDNCSLHGISLPAAYPGLPGLPPVILPGMNGPSSLPGFPQ-NSNTLTPPGAGMLGFPSSATSSPALSLSSAPTKSLLQTPPPPPPP-PPPPPPPPSSLSGQQTEP-----------------------QNKE---PEKKQTKPNKVKKIKEEESEAIKPEK-HPKKEEKISSALSVLGKVVGETHMDPTQLQALQNAIAGDPTSFIGGQFLPYFIPGFASYFTPQLPG-TVQGGYLPPVCGMES-LFPYGPAVPQTLAGLSPGALLQQYQQYQQS--LQDSLQKQQKQQQEQQQK------------------------------PVPAKTAK---GEGDQPQSSNEASETKEEKSTAPEST------KEEAQLDSK---TTEFSDTCVVPFVKYEFICRKCQMMFTDEDATVNHQKSFCYFGQPLIDPQETVLRVPVS--------------------KYQCLACDLALSGNEALSQHLQSSLHKEKTIKQAMRNAKEHVR-LLPHS----VCSPPPNTSSTSPSAASSN--NTYPHLSCFS--------------------------MKSWPNILFQASARKAASSPSS----PPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQK-LQDLDNSLEVKAKPASGLDGN-----FSSVRMDMFSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJN2-1", "uniprot_id": "ZFHX4_MOUSE", "id": "Q9JJN2-1", "name": "Zinc finger homeobox protein 4", "aln": "METCDSPPISRQENGQS-------TSKLCGMTQLDNEVP--EKVAGIEPD--------RENSSS--HDNLKTDE--RKSEVLLGFSIEN-----AAATQVTSAKEIPCN------------ECATSFPSLQKY-------------MEHHCPNARLP-VLKDD-ESETSELED--SDVENLTGEIVYQPDGSAYIIEDSKESGQN--AQTGANSKLFSTAMFLDSLASAGEKSDQSSTAPVSFYPQIINTFHIASSLGKPFT-ADPAFPNTSALAGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEERRLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPNFSTTNLIGPDPTFRGLWSAFHVENGDSLQAGFAFLKGSASPSSSAEQPLGITHMPKAEVNLGGLSSLVVNTPITSVSLSHLSSESSKMSESKDQENNCERP--KESTILHPNVGCPVKSEPTEPGDEDEEDAYSNELDDEEVLGELTDSIGNK---------------------------------------DFPLLNQSISPLSSSVLKFIEKGTSSSS-GTIAED------TEKKKQ---AAATGR-------SNGNVTNSYSIGGKDFADGSISRDGTTAA-PSETTHGDEDSSTT-HQHGFTPS-------------------------TPGTPGPGGDGSPGNGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP-GGSCVYCKTGQPHPRLARGESYTRGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGN----GEQVFGHSAPTPNTSLSG----------------------------------------------CGTPSPSKPKQKPTRRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLA---------------------PAEAELYQYYLAQNIGLTG------MKLENP-AETQLLLNPFQFDSAT-AAALAPGLG--------------------------ELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVNSERS----LPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGG--------KSNEWRLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQ------KQEGAVNSES-CCYYCAVCDYSSKIKLNLVQHVRSVKHQQTEGLRKLQLHQQGLPSEEDNLSEIFFVKECPANELETASLGARNGEDELIEQQLKAASEEPSEDAGDPLKPPTVAEDDEKEAHKRDNSEGKISTKDPEVIVPEKEPKVVTG-ATQPLLLAKEDSTGTKRSKPTEDNKFCPEQFYQYPCCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMLNSMLLPAAAPEKSEQDPP---TALTAEGSGKCSGDGPVDDKSMSGLEDSKVGVEIK--NEEQKPAKEPVEASEWNKTSSKDVNISDALQDQLNEQQ-KRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCTLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPMNGELWAESETMTQDDHGIDQEM-ERE-YEVDHEGKASPVESDGSSIPDDLGLEPKR-TLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVP-----QEANSSTDNKPYKCSTCSVAYSQSSTLEIHMRSVLHQTKARAAKLEPSRHLP-----SGHSITAAVNS---------------------------------PGQGMLESMSLASVNS-----KDTHLDAKELNKKQTPELISAQPT-----------------HHPPPRSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQP-QFLFPFYIPGAEFSLGPDLGLPTSTTFGVPGMT-GMAGSLLEDLKQQIQTQHHVGQTQLQFLQQ-AQQYQAVQPQLQPQNQQP-PLPQQQQPQQQPSKLLKQEQGSLASTDCQLMKDMPSYKEAEEVTEKQE-KPKQEFINDTEGLKDSKDIKKQKSLEPCIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKS---------------GEGENSDKLECGICGKLFSNVLILKSHQEHVHGQFFPYGALEKFARQYREAYDKLIQF------------LLPPLPPAPPQPSTLGPVKIPNTVSAPLQAPPPTPP------------------SAPQQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDT-LSADLTQLCQQQLGIDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVVKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDAAFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAEA-KDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVLYKHCMVSGQTDTAKSTATLVAS----SGSGTSTPLIPSPKPEPEKNSPKTEYPGEKTKQSDPSLP-QGTKSAPSSVLTSSEPQQA----------------------SIPQPPTQP--PKQPQLIGRPPSASQTPIPSSPLQISMTSLQNSLPPQLLQYPCDQCTLAFPTLELWKEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQTSTAHTTAPASVAASLKRKLEDKEDNNCSEKEGG--NSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSTENELASTVSTPVSKTAELSPKNLLSPSSFKAECPEDVENLNAPSADAGYDQSKTDFDETSSINTAISDATTGDEGAADMEN-TGGSGEVKPALSPKETKTLDSLQKPATTPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSK--SNDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKERKFKIN---IGKPFMINQSGTDGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQ----QQGITDNCSLHGISLQAAYPGLPGLPPVILPGMNGPSSLPGFPQ-NSNTLTSPGTGMLGFPSSATSSPALSLSSGPTKSLLQTPPPPPPP-PPPP----SSLSGQQTEP-----------------------QNKE---SEKKQTKPNKVKKIKEEESEAIKPEK-HPKKEEKISSALTVLGKVVGETHMDPTQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFSPQLPG-TVQGGYLPPICGVES-LFPYGPAVPQTLAGLSPGALLQQYQQYQQS--LQDSLQKQQKQQQEQQQK------------------------------PVPAKTAK---GEGDQPQSSNEASETKEEKSTAPEST------KEEVQLDSK---SAEFSDTCIVPFVKYEFVCRKCQMMFTDEDATVNHQKSFCYFGQPLIDPQETVLRIPVS--------------------KYQCLACDLALSGNEALSQHLQSSLHKEKTIKQAMRNAKEHVR-LLPHS----VCSPPPNTSSTSPSAASSN--NTYPHLSCFS--------------------------MKSWPNILFQASARKAASSPSS----PPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQK-LQDLDNSLEVKAKPASGLDGN-----FNSVRMDMFSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UP3-1", "uniprot_id": "ZFHX4_HUMAN", "id": "Q86UP3-1", "name": "Zinc finger homeobox protein 4", "aln": "METCDSPPISRQENGQS-------TSKLCGTTQLDNEVP--EKVAGMEPD--------RENSST--DDNLKTDE--RKSEALLGFSVEN-----AAATQVTSAKEIPCN------------ECATSFPSLQKY-------------MEHHCPNARLP-VLKDDNESEISELED--SDVENLTGEIVYQPDGSAYIIEDSKESGQN--AQTGANSKLFSTAMFLDSLASAGEKSDQSASAPMSFYPQIINTFHIASSLGKPFT-ADQAFPNTSALAGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTFRGLWSAFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPITSVSLSHSSSESSKMSESKDQENNCERP--KESNVLHPNGECPVKSEPTEPGDEDEEDAYSNELDDEEVLGELTDSIGNK---------------------------------------DFPLLNQSISPLSSSVLKFIEKGTSSSS-ATVSDD------TEKKKQ----TAAVR-------ASGSVASNYGISGKDFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPS-------------------------TPGTPGPGGDGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP-GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGN----GEQVFGHSAPAPNTSLSG----------------------------------------------CGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLA---------------------PAEAELYQYYLAQNIGLTG------MKLENP-ADPQLMINPFQLDPAT-AAALAPGLG--------------------------ELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERS----LPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGG--------KSNEWRLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQ------KQEGAVNPES-CYYYCAVCDYTTKVKLNLVQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDLTEQH---------EEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDS----------VSVAGGTQPLLLAKEEDVATKRSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTP---AAVTAEGSGKYSGESPMDDKSMAGLEDSKANVEVK--NEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQ-KRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEM-ERE-YEVDHEGKASPVGSDSSSIPDDMGSEPKR-TLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVP-----QETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVA-----GGHSIAANVNS---------------------------------PGQGMLDSMSLAAVNS-----KDTHLDAKELNKKQTPDLISAQPA-----------------HHPP-QSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQP-QFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMT-GMAGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPE-KPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKS---------------GEGENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDA-LSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAET-KDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAAS----SGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQA----------------------STAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGG--NSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSENELASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSSINTAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSK--SNDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKIN---IGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQ----QPGMMDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQ-NSN----ISAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPP-PPPPP--SSSLSGQQTEQ-----------------------QNKE---SEKKQTKPNKVKKIKEEELEATKPEK-HPKKEEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPG-TVQGGYFPPVCGMES-LFPYGPTMPQTLAGLSPGALLQQYQQYQQN--LQESLQKQQKQQQEQQQK------------------------------PVQAKTSK---VESDQPQNSNDASETKEDKSTATEST------KEEPQLESK---SADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVNHQKSFCYFGQPLIDPQETVLRVPVS--------------------KYQCLACDVAISGNEALSQHLQSSLHKEKTIKQAMRNAKEHVR-LLPHS----VCSPNPNTTSTSQSAASSN--NTYPHLSCFS--------------------------MKSWPNILFQASARRAASPPSS----PPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQK-LEDLDNSLEVKAKPASGLDGN-----FNSIRMDMFSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NXU9-1", "uniprot_id": "F6NXU9_DANRE", "id": "F6NXU9-1", "name": "Zinc finger homeobox protein 3", "aln": "METCDSPSLLRQENGQQ-------ISKLRETTHLDNEVP--EKVPGMEPD--------KENSPA--DDNLRTEES--LREIASGLSAEN-----AIG---TATKEIPCN------------ECATSFSSLQKY-------------MEHHCPNARLP-LLKDENESEVSDLED--SDVENLTGEIVYQPDGSAFILEDSKEGGQN--AQSGVKS-LFSPALFSNSQTAAGDKTEQSATAPMSFYPQVINTFHIASSLGKPFT-ADQAFPNTSALAGEGPVLHSFRVYDLRHKSDKDYLTIDGAAKNSCVSKDVPNNVDLSKFDGCISDGKRKPILMCFLCKLSFGYSRSFVTHAVHDHRMTLNEQEQKLLSNKYVSAIIQGIGKDKEPLISFLEPKKNNSMLPHFSTANFMGPDPGIRSLWNTFHMENGDSLQAGFAFLKGSASLASSADQSPRSAQMPKAELNLGVMATSALKSPVSSVSLQRSSPGAG----YRDQESNCERQ--KDLSTLHANGELPIKSEPRDVADAEEEDMYSNELDDDGVC-ELEDSTSSK---------------------------------------DFPLLNQSISPLSSSVLKFTERGTTSSV--TVAND------FEKTKH----AAANL-------DYSNDSTSG--GSKDSCDSISGRGGSPPSLPLDLMRRDDESPGPLHQHAATPS-------------------------TPGTPGPG-EGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLDAHMKEKHPES-GGSCVYCRTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQTLQNGG----TEAIYNHTTPVTNTSLTG----------------------------------------------CGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLA---------------------PAEAELYQYYLAQNIGLTG------MKLENP-SDPQMMINPFQLDPST-AAALTPGHVNNELPAELRLASGQLMGDDLSVLSAGELSPCINDPLLKLFQCAVCNKFSSDSLEALSGHVATERS----LPEEEWRAVMGDVYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGG--------KANQWRLKCIAIGNPVHLKCNACDYYSNSVEKLRLHATNQRHEAALKVYKHLQ------KQESACNSES-CYYYCALCDYSSRAKLNLLQHLRSVKHQQSEGLRKLQLHQQGLPPDEDNLADIFLVKDCPPNESEEP-----------------------GEDSEEFPQASSLAAAEDKDSSKRDAIEGKTTEKDSRINTLAKETLGIATAGKQSLQQEKENDTPPKRPKSAEEKTLSNEQVQQCPYCNYSNKDANRLQLHIMSQHSMQPVISCPLCQDVLSNKIHLQLHLTHLHSVAPDCVEKLLMTVAGPDLPVPSSLLSASLQDKVPSLMDT---SAVNPEGSGKTMGNSSKDLKNGTGQD--KSEVDLT--SEELKPLKEAAEAPDWKKASGQDRKSPDALQEHLSDLQ-KRQQLSVSDRHVYKYRCNHCSLAFKTMQKLEIHSQYHAIRAATMCTLCQRSFRTFLALRKHLETGHPELTEAEVQQLCGNLPLNGDISESEMRALEEAQAFENEL-DKD-EELDQEGKASPTGSDSSSLLDDMGSEPKR-TLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVIQEASSPVP-----QETSNNVDNKPYKCNICNVAYSQSSTLEIHMRSVLHQTKARTAKLETSTSTG-----SGSSGSTSSKSPVP------------------------------PNHGNTDSASAAPVSTN----KENTVDAKEVTMKQTTEHIPVQP------------------NHPPTQSPAQLQMQLQHELQQQAAFFQPQFLNPAFFPHFPMTPEALLQFQQP-QFLFPFYIPGAEFNISPELALHS-AAFGMPGMT----GSFLEDLKQQMQQQHQLGQQQQLQLSQQQAQQQASQSQMQQQKVQQ------------------QSHKPKTESNHNVLSEIQMSRDAEEHLEKQEGKAKQDTANENDNGKDAKDNRKPKFSEPLIPPPRIISGARGNAAKALLENFGFELVIQYNENRQKSQKKNK-----------------EDELTDKLECGLCGKLFSNMLILKSHQEHIHGQFFPYVELEKFAQQYREAYDKLYPINPASPETPPPPPPPPPPPPPPAPLNTLPANASVGKSQTPSPAPIQTPQQAPQPPPPPPPPPP----TAPPQVQLPVSLDMPIFPPLMMQSVQHPGLPPQLALQLPTMDS-LSSDLTQLCQQQLGLDPNFLRQSQFKRPRTRITDDQLKILRAHFDINNSPNEEQIQEMADKSGLPQKVIKHWFRNTLFKERQRSKDSPYNFNIPPMTTLEDIRLESQVNLLEYTRIDSASNKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKTYENQADT-KESEKKELTNERYIRTNNMQYQCKKCSVIFPRIFDLITHQKKQCYKDEDDEAGDEHILEDLSENIEQSLAKPMEAAKQS--------FVTA----SSSGSSSPLMPSPRPDIGKTSPKPELLNEKSKLG-ETAPLQTPKNP-----NELKPSKA----------------------STPQPLSQK--VPQPQLSRPHSQPQSTPVPSSPLSLALSSLNNSLPPQMLQYHCEQCKIAFPTVELWQEHQHMHFLAAQNQFLHSQFLERPLDMPYMIFDPNNPLMTGQLLSGALSQIPTASNSGLTMN----SNSLKRKLDEKEDG-SHEKDGL--NSAEDQHRDKRLRTTITPEQLEILYDKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPSQTHKKCPFCRALFKAKSALDSHIRSRHWHEAKQAGFSLPPSPMMPQDDEGQSPHKYSFSDYLQMP-TKIEMN-ENEPPTASSTPV-KPSETLFKNFLNIPSLKAEHSDELEALNMSSAEASFDTNKMDFDETSSINTAVSDATTGDETNNEVEN---------LTINGSEKMIEN---KSNQAQTSDMNEDRFPFNMVSPALSFSGKDSDYFN--YRDDDFDDNADRSETSSLADPSSPSPFGSTNPFKSSKAGGERPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKIN---IGKPFMISQGSPDGPRPECTLCGVKYTARLSIRDHIFSKQHIAKVQETLGNQVDREKDYLAPTTVRQLMAQQELDRLKKATDVLNLPAQ----QQPAVDNNALHGLSLPTAYPGISGLPPVLLPGVNGPSSLPGFPP-NTPALASPGAGMLGFPTPATPSPAMSLSSTPTKTLLQTPPPPPPPQPSALPLPPTPLAANQTEQ-----------------------HIKE---SEKD--KKLEKPKVKEREADTARPETPIVKKKEKPSPPLSMLGKLGSEGQMDPAQLQALQNAIAGDPGSFLGGQFLPYFIPGFASCFSPQLPG-GVQGGYFPPLCGMEN-LFPYGPAMPQAIAGLSPTALLQQYQQYQQS--LQDSLQKQQHQQQQQQKQSE-----------------------PQRKTPAPMKSTS---AQSNSLK-PKETVETKDDKGSSTEST------NEEPQTNTK---SSGFPDAFIVPSIKHEFICRKCQMIFADEDSAARHQKSFCYFGHPFIDPQETVLRKAVS--------------------KYNCIACNVSVSGNEALGQHLQSSLHKEKTIKQAMRNAKEHAR-LLPHS----VCSPNPNTTSTSQSAASSN--NTLPHLSHLS--------------------------MKSWPNILFQASARKAASCPSAS---PPPLSLPSTVTSTSCSTSGVQTSLPTESCSDESDSELSQK-LDDLDNALEAKAKAASGLDGN-----FSSMRMDMFSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0L407-1", "uniprot_id": "A0ABK0L407_RAT", "id": "A0ABK0L407-1", "name": "Zinc finger homeobox protein 3", "aln": "MEGCDSPVVSGKDNGCG------IPQHRQWTELNSTHLP--DKPSSMEQP------TGESHGP---LDSLRAPFNERLADSSTSAGPP----------AEPASKEVSCN------------ECSASFSSLQTY-------------MEHHCPGTHPPPALREESASDTSEEGEEESDVENLAGEIVYQPDGSAYIVESLSQLAQSGAACGSSSGSGGVPSLFLNSLPGVGGKQGDP-SCAAPVYPQIINTFHIASSFGKWFEGSDQAFPNTSALAGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEEERKLLSNKNTSAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGPGHSFYGKFSGICMDGEEALPAGAAAGP---------EQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGD----KREVG-DQDCFSEKVEPAEEEEAEEEEEEEEEAEEEEEEEEEEEEEDE---GCKGLFP---NELEEELEDRPPEESGATAGGGSKKDLALSNQSISNSPLMPNVLQTLSRGTASTTSNSASNF-VVFDGANRRSRLSFNSEGVR-----------ANVAEG-RRLDFADESANKDSATAPEPNES-TEGDD--GGFAPHHQHAG-----------------SLCELG-VGECPS--------GSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP-GGSCVYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGG----GEQVFSHSAGAAAAAAAA------------------------------------AAAAANIGSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPS-----------------PAEAELYQYYLAQNMNLPN------LKMDNTASDAQFMMSGFQLDPTGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLG--ESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERS----LSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGG--------KANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQ------QHESGVEGES-CYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEA-----------------------IEDAEGPSEASADPEELAKDQGSSGGEEGQSK-RTASSSQAEKELTDSPAASKR-SSFPGSSETPLSSKRPKASEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEKLIMTVTAPEMVMPSSMFLPAAAPDRD--------GNPNLEEAGKQPETSEDLGKNTLPSAIMEHSGDLKPSSADPSCMREDSGFLCWKKGCNQVFKTSATLQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEE-DKE-EESDLEDKQSPTGSDSGSVQEDSGSEPKR-ALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQP-----EPTSS-PDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASGSS---NGTGNSAGVSLSSSTPSPVGSS--GANNTFTAANPSSATMAPSVNALSQVPPESVVLPPLGNPISANISSPSEPKETNRKKLADMIASRQQQQQQQQQQQQQQ-----AQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQHHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGS---GPGLLEDLKAQIQIPQQS--HPQILQQQQQQQQQQSQLSLSQSHSALLQPS-------------QHPEKKNKVVIKEKDKESQREREGPEGAEGNP-GPKESLPDALKAKEKKELAPGGGSEGS-MLPPRIASDARGNATKALLENFGFELVIQYNENKQKAQKKNG-------------KAEQGSESLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYREHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ------------------PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEP-LPADLAQLYQHQL--NPTLLQQ-QNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPQKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEG-KDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEDEEGQDDSQNEDSMDA-MEILTPTSSSCSTPMPSQAYSTPAP--SSASTAPSAFLQLTAETDELATFNSKAEASDEKPKQ-ADPPSVQPNQTQEKQGQPKPEVQQQ-EQAEQKTNVPQPKLPQLA-APSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTP-TSTMNTLKRKLEEKASGASPGENDSSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMK----GDIFDGTSFSHLPPSGSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGLEDFESPSMSSVNLNFDQTKLDNDDCSSVNTAITDTTTGDEGNADNDS------ATGIANETKSS-APNEGLTKAAMMAMSEYEDRLSSGLVSPAPSFYSKEYDNEG----------TVDYSETSSLADPCSPSP-GASGSAGKSGDSGDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKLS---MAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQ----QQGMFDNAPLQALNLPTTYPALQGIPPVLLPGLNSPS-LPGFTPSNTALTSPKP-NLMGLPSTTVPSPGLPTSGLPNK-PSSASLSSPTPAQATMAMAPQQPPQPQQPQ--PQVQ-PPPPPAAQQIPTPQLPLPQQ--RKDKDGEKGKEKEKAHKGKGEPPPVPKKEKGEAPTAATATISAPLPAMEYTVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPG-ALQSGYLQPMYGMEG-LFPYSPALSQALMGLSPGSLLQQYQQYQQS--LQEAIQQQQQQQQQQQQQQQRQLQQQQQQQQKVQQQQQQQQQQQQQQQPKASQTPVPQGPASPDKDPAKESPKPEEQKNVPREVSPLLPKPPEEPEAESKSASADSLCDPFIVPKVQYKLVCRKCQAGFGDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGSGGGG----GGGGSGGGGGGSYHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPS-LLPHS----ACFPDPSTASTSQSAAHSN--DSPPPPSAAPSSSASPHAS-----------------RKSWPPVG-SRASAAKP-------PSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQK-SDGPASPVEGPKDPSCPKDSG-----LTSVGTDTFRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61329-1", "uniprot_id": "ZFHX3_MOUSE", "id": "Q61329-1", "name": "Zinc finger homeobox protein 3", "aln": "MEGCDSPVVSGKDNGCG------IPQHRQWTELNSAHLP--DKPSSMEQP------TGESHGP---LDSLRAPFNERLADSSTSAGPP----------AEPASKEVSCN------------ECSASFSSLQTY-------------MEHHCPGTHPPPALREESASDTSEEGEEESDVENLAGEIVYQPDGSAYIVESLSQLAQSGAACGSSSGSGAVPSLFLNSLPGVGGKQGDP-SCAAPVYPQIINTSHIASSFGKWFEGSDPAFPNTSALAGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEEERKLLSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTGNLIGPGHSFYGKFSGIRMEGEEALPAVAAAGP---------EQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGD----KQESGGHQDCFSEKVEPAEEEEAEEEEEEEEEAEEEEEEEEEEEEEEEE--ASKGLFP---NDLEEELEDSPSEESGPPAGGTTKKDLALSNPSISNSPLMPNVLQTLSRGPASTTSNSASNF-VVFDGANRRSRLSFNSEGVR-----------ANVAEG-RRLDFADESANKDSATAPEPNES-TEGDD--GGFVPHHQHAG-----------------SLCELG-VGESPS--------GSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP-GGSCVYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGG----GEQVFSHSAGAAAAAAAA------------------------------------AAAAANIGSSWGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPS-----------------PAEAELYQYYLAQNMNLPN------LKMDSTASDAQFMMSGFQLDPTGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLG--ESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERS----LSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGG--------KANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQ------QHESGVEGES-CYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEP-----------------------VEDAEGPSEASADPEELAKDQGS-GSEEGQSK-RAASSSQAEKELTDSPATTKR-TSFPGSSETPLSSKRPKASEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPLLRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEKLIMTVTAPEMVMPSSMFLPAAAADRD--------GNSTLEEVGKQPEASEDPGKNILPPASMEHGGDLKPTSADPSCGREDSGFLCWKKGCNQVFKTSATLQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEE-DKE-EESDLEDKQSPTGSDSGSVQEDSGSEPKR-ALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQP-----EPTSS-PDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASGNS---NGTGNSGGVSLSSSTPSPVGSS--GANNTFTATNPSSAAMAPSVNALSQVPPESVVMPPLGNPISANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQ------AQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGS---GPGLLEDLKVQVQIPQQS--HQQILQQQQQQ----SQLSLSQSHSALLQPS-------------QHPEKKNKVVIKEKDKESQREREGPEGAEGNT-GPQESLPDASKAKEKKDLAPGGGSEGT-MLPPRIASDARGNATKALLENFGFELVIQYNENKQKAQKKNG-------------KAEQGGESLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYREHYDKLYPLRPQTPEPPPPPPPPPPPPLPTAPPQPASAPAIPASAPPITSPTIAPAQ------------------PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEP-LPADLAQLYQHQL--NPTLLQQ-QNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPQKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEG-KDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEDEEGQDDSQNEDSMDA-MEILTPTSSSCSTPMPSQAYSTPAPSAAAANTAPSAFLQLTAETDELATFNSKAEASDEKPKQ-ADPPSAQPNQTQEKQGQPKPEMQQQLEQLEQKTNAPQPKLPQPA-APSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTP-TSTMNTLKRKLEEKAS-ASPGENDS-GTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMK----GDIFDGTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDDCSSVNTAITDTTTGDEGNADNDS------ATGIATETKSS-APNEGLTKAAMMAMSEYEDRLSSGLVSPAPSFYSKEYDNEG----------TVDYSETSSLADPCSPSP-GASGSAGKSGDGGDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKLS---MAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQ----QQGMFDNAPLQALNLPTTYPALQGIPPVLLPGLNRPS-LPGFTPANTALTSPKP-NLMGLPSTTVPSPGLPTSGLPNK-PSSASLSSPTPAQATMAMAPQPPPQPQQPQ--PPVQQPPPPPAAQQIPAPQLTPQQQ--RKDKDGEKGKEKEKAHKGKGEPLPVPKKEKGEAPPAGTGTISAPLPAMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPG-ALQSGYLQPMYGMEG-LFPYSPALSRPLMGLSPGSLLQQYQQYQQS--LQEAIQQQQQQQQQQQQQQQQQQRQLQQQQQ--QQQQKVQQQQQQQQQPKASQTPVPQGAASPDKDPAKESPKPEEQKNVPRELSPLLPKPPEEPEAESKSASADSLCDPFIVPKVQYKLVCRKCQAGFGDEEAARSHLKSLCCFGQSVVNLQEMVLHVPTGSGGGG----GGGGGSGGGGGSYHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPS-LLPHS----ACFPDPSTASTSQSAAHSN--DSPPPPSAAPSSSASPHAS-----------------RKSWPPVG-SRASAAKP-------PSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQK-SDGPASPVEGPKDPSCPKDSG-----LTSVGTDTFRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15911-1", "uniprot_id": "ZFHX3_HUMAN", "id": "Q15911-1", "name": "Zinc finger homeobox protein 3", "aln": "MEGCDSPVVSGKDNGCG------IPQHQQWTELNSTHLP--DKPSSMEQS------TGESHGP---LDSLRAPFNERLAESTASAGPP----------SEPASKEVTCN------------ECSASFASLQTY-------------MEHHCPSARPPPPLREESASDTGEEGDEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSLPGAGGKQGDP-SCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGPGHSFYGKFSGIRMEGEEALPAGSAAGP---------EQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGE----KQEVG-DGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDE---GCKGLFP---SELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVLQTLSRGTASTSSNSASSF-VVFDGANRRNRLSFNSEGVR-----------ANVAEGGRRLDFADESANKDNATAPEPNES-TEGDD--GGFVPHHQHAG-----------------SLCELG-VGECPS--------GSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP-GGSCVYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGG----GEQVFSHTAGAAAAAVAA------------------------------------AAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPS-----------------PAEAELYQYYLAQNMNLPN------LKMDSAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLG--ESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERS----LSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGG--------KANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQ------QHESGVEGES-CYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEA-----------------------IEDVEGPSETAADPEELAKDQEG-----------GASSSQAEKELTDSPATSKR-ISFPGSSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRD--------GNSNLEEAGKQPETSEDLGKNILPSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEE-DKE-EESDLEDKQSPTGSDSGSVQEDSGSEPKR-ALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQP-----EPTSS-PDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASGSS---NGTGNSSSISLSSSTPSPVSTS--GSN-TFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGT---GPGLLEDLKAQVQVPQQS--HQQILPQQQQN-----QLSIAQSHSALLQPS-------------QHPEKKNKLVIKEKEKESQRERDSAEGGEGNT-GPKETLPDALKAKEKKELAPGGGSEPS-MLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNG-------------KTDQG-ENLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ------------------PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEP-LPADLAQLYQHQL--NPTLLQQ-QNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEG-KDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEDEEGQDDSQNEDSMDA-MEILTPTSSSCSTPMPSQAYSAPAP--SANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKL-AEAPSAQPNQTQEKQGQPKPELQQQ-EQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTP-TSTMNTLKRKLEEKAS-ASPGENDS-GTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMK----GDIFDGTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDDCSSVNTAITDTTTGDEGNADNDS------ATGIATETKSSSAPNEGLTKAAMMAMSEYEDRLSSGLVSPAPSFYSKEYDNEG----------TVDYSETSSLADPCSPSP-GASGSAGKSGDSGDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKLS---MAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRIKKANEVLGLAAQ----QQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPS-LPGFTPSNTALTSPKP-NLMGLPSTTVPSPGLPTSGLPNK-PSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPG-ALQSGYLQPMYGMEG-LFPYSPALSQALMGLSPGSLLQQYQQYQQS--LQEAIQQQQQRQLQQQQQQK-----------------------VQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESK--SADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPS-LLPHS----ACFPDPSTASTSQSAAHSN--DSPPPPSAAAPSSASPHAS-----------------RKSWPQVV-SRASAAKP-------PSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQK-SDGPASPVEGPKDPSCPKDSG-----LTSVGTDTFRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QI68-1", "uniprot_id": "A0A8M9QI68_DANRE", "id": "A0A8M9QI68-1", "name": "Zinc finger homeobox protein 3", "aln": "MESCESPVVSGTDDGLGSSATSQQHHPQPWNDHPNAQVPPCNQSPSLEPLSLSAPHSAQIQNPSTHCEALREQQKQTLSQAPSDISTSRQLHLKREGLEEEEQEGVSCGEEDEDLEDLDEMEIDSCFPSLQPFPGVPMVPSGGGMPMLMRQQPSHRRGAMESGSEEGEEEEEEESSDVENLAGEIVYQPDGSAYIVESLSQLIQSDGSMEPG--------LLSSNSLTSGGKPGEP-VGTSSVYPQIINTFHIASSFGKWFGSSDQGFPNTSTLTGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKKSCVSKDVPNNVDFSKFDGLALYGKGKPILMCFLCKLSFGYARSFVTHAVHDHRMTLCEDERRLLGHKHASAIIQGIGKDKEPLISFLEPKNKNSPSPPTLVP--MNSGQSFYGTFSGVHLEGGSSSEGGESLLN---------KDSDSGLQQ-QALLTLGGLGSPKASS-LTSTPGPAKDSSTLSKPQGRRTDGSVGKEGTHRGEDGNAEICERKTLLPGEEMPSDEEDELLLEEEDEEVEDEGTAVACSGSSSSSGRFVGEPAVSNQSISKSPLLMPSSALQPSACLSAASPALSSKFSASMSSSIRGAEDGMAADGGGRTSELPLSFNCQGSTVPMAMAAVAGRGGEEDGAACSAASTSSPLASNAAAEESANRDSATAPEPNECPAEGDEDNGALLHHHLHHHHHHLHPSPNAHTHLHHTAACDLSGISECTQNHGAGGSGGSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPDS-GGSCVYCSSGQSHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQTLQNGGTIPTGEQVFGHAPGGVVPVSSASQPGSHHPSHHHHP----------------------AQSSTHMTGPCGAPSPTKPKSKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMSQMQHGR-LGLGAMPS-----------------PSEAELYQYYLTQNMSLPPG-----LKMDPSGADAQFLLGGFHLDPN--MAALAPALVGGDIAMDVRLGGGQLVSEELMTLG--ESLSQTSDPSLKLFQCAVCNRFTTDNLDVLGLHMSAERS----LPEEEWRAVVGDSHQCKLCHYTTQLKANFQLHCKTDKHVQKYQLVAHIKEGG--------KGNEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRMHTVNSRHEASLKLYKHLQ------QHENAVEGES-CYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEEEELSAIFTIRKCPSADTGEL-----------------------SEDVEAASETTTDQEDQTKDKES--GGERELT-KGTASNQPERDQTDSPVPSKRPSSRSETAESPLSSKRPRTTEKSSGEQMYQCPYCKFSNTDLNRLRMHVMTQHSVQPMFRCPLCQDMLNNKVHLQFHLTHLHSVAPDCVDKLIATVAA-SEVLPASMFIPVPGPEKDTQTAPQSMANSNSDDTKKLTEVADAEPEKGVCLTSDTAEARKSPLEEQQPARDDSTGFLCWKKGCNKVFKSSSALQMHFNEVHNKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTLQALKKHLETSHLELSEADIQQLYGGLLMNGDLMIMGDPSLGEDQGGLLDD-EKEGDESDPEEKQSPTGSDSGSLLEDSGSEPKR-ALPFRKGPNFTMEKFLDPSRPFKCTVCKESFTQKNILLVHYNSVSHLHKVKRALQESTTGQP-----EPTSS-PDNKPFKCSTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAAGGSSTAVSSSGPSGSTSNSTSTPSPIPATNSTTSSSNSSSSPAGAQTAQSIIGGNHLSSHSHSVENLGN--SASHTSSSENHEVKKKKFSDMLSSRSHQQQLQQQ----------QQQLAQAQAQAQAQLQQELQQ-AALLQSQLFNP-LLQHFPMTTDALLPLQQQ-QLLFPFYIPGAEFQLNPEMNLNSSS--LNLSGS---TASLLEEQKNSVQQAQQSCLQQQLMHHHLQQQHQAHSHSQGSSQMALLQQSA-----------LSHPVDKKTKPSPHTEKERDLPKDKEISDKSED-HVPKDLSDKSKEKIDATQALVNVNHDSGFPPPRIASDARGNATKALLENFGFELVIQYNENKQKAQRKSTGSLPGCTGTAGFTRVVDPIEGLEKLECESCGKLFSNILILKSHQEHIHQAFFPFRFLERFAKEYREQYDKLYPLRPQTPEAAPAPPPPPPPP-PPPPPQRAPTPNIPVSAPTLTPPTAPTPQ------------------PPVPLSQIPMAMDLPLFSPLMMQPMSLQSLPSQIPAQLPTVEPSLATDLAQLYQQQL--TPAMLQQ-QNKRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFNNPPITTLEETKIDSKPPSPEPLKQEAYGNKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGDGVKEGDRRELSNDRYIRTTNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEEDDGQYDSLNEDSLDLSHEYYTPSGSSGQTPMPSSSSLCPLP-------PSSAFSHIASSEKEEPTPANTSNSFDEKSRHSAETTLGQREQTSLKQETSHPSETPQQRPQREEKMHAVPKNSKLS-SPSLSQQQQHSGPSVSHTSQTSQS----SHMALNPHLASASQQ--QLAQQMIPYQCEQCKLAFPSFEHWQEHQQLHFLSVQNQFIHPQFLDRPMDMSFMLFDPSNPLLASQLLAGAIPQMSSNSATSPSTP-TSTMNSLKRKLEEKAG-TSPGESDS-MNSGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLALSGLLPEQE-AMQLK----MDPLDISSYAHLAQSNNDAQCSSLSPISKVMDLSPRALLSPTSIKVEGVEEFESPTISSVNTNFDHNKLDNDDCSSVNTAITDTTTGDEANVDNDS------ADAKHSQNSGDFLSKSGGTAPS----IENDEQMSSGLVSPATSYYTKDFENEN----------MIDYSETSSLADPCSPSP-GASGSR--SIDSGDRPGQKRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKAKLS---MAKHFGINQTSYEGPKTECSLCGVKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQEMDRIKKANEVLGLAQQQAMQQQGMFDTPALQALNLQSGYPNLQGIPPVLLPGVGGPS-IPGFNSSNSALTPPKPPNLLNMPGASVPSPSLPTSGLPNKTPSSSSLASPSPAQASTSVAHSSPTPTSTTN--SLMTQPGARPEAPKDRDPERAREKE---KPKEKAEKSSTPSSAGGTPAPSTSAASAKKEKTDTAVPATSMPTPGMEYVVDTAQLQALQAALASDPTALLTSQFLPYFMPGFSPYYAPQIPG-ALQGGYLQPMYGMES-LFPYNPALSQALMGLSPGSLLQHYQQYQQS--LQEALQQQQRQLQQIQ-------------------------------QPKASQTSQ---NSVDRKDSAKDSVKTE-QKSTPSAETSSTHNNVAAEQHEVDGKGADPHLDQYIVPKVQYRLACRKCQAVFSKEEAAISHLKSICFFGQSVANLQEMLLRVPNS-------------GNAAEGGLYDCLACDTTLEGDKALSQHLDSALHKHRTIKRS-RNAKEHATNLLPHSS---ACFPSPNTASTSQSATHSNNTTSPPPTTSATTPSSSTTASSCTSTSFTASPLNTTATGKSWSQAPFSRALAGQPNPPSSALSSFPPVSSPSTVTSSSLSTSGVQTSIPTDVFTDESDSDSSQKSADRLGRPAEEPQQPGCLKDSSSCSSNLTSVGSDSIRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q7K3-1", "uniprot_id": "F1Q7K3_DANRE", "id": "F1Q7K3-1", "name": "Zinc finger homeobox protein 3", "aln": "----MCSVAQRMECCDS-------VSNNGAAGPHTQQPP--GLCRSLAPS------------------ALLLARDQAIHRSTATPSKQG---------GQAEVAEVEG--------------FAGRYEEKLRK---------------KQVNECSTGEVLKDAVERETADEEEEGEDVERPIGEILYQPDGSAYVMDSKLTSGAP--------------------------------SSSLGAPTSIIRTCFISLSQ--------------------SPTPQIFRVFQLHNLGD-----SDSLALMTCQSKDSTPDVAGSSETGVMWSGPPKPILMCFLCRLSFGRSHSFRAHASVQHNITFSDEEQHLLLFKHASAILQPAGPGNLPLLCFLKPKRNCESVVPLNLASSNSVNSTENTARRKENTEPLTSKP-GLSLLPSP----PRTSPATSVPSPAKDPSTLGREGTQRGKVEEIRKDGESSEEGERRLCLEVGSTVDCNSAHSISSSSGQEHITEAALSNQSISKPPNSVTIATSFMNNTKTLTDSESECGTS------------------------------------FNCHDPAPASLVVVNPSTVTTTEQLANQESATATKPNDQLENGSAIAIEPTASLSEDDR-----------RAVTHSDLPNNHSHSMSPTLSPTLPQTTQPILEEGHSDTASRGRLVVAS---------------------------------------DGGFVAAGDDAQGSSYSFSIQASLAHTRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPESETEQCPYCSSGQSHPRLARGETYSCGYKPFRCQVCQYSTTTKGNLSIHMQSDKHLNNMQSLQSQP------QPHAHSPAPQPNPLTHS------------------------------------LPTLTHPTRANSPSPSKLRGRASWRCEVCDYETNVARNLRIHMTSEKHTHNVLLLQQNLAHMQRQRKHNAS-------------------------ELFRHCQPQSQ-LPD------------------AIT---------------------------------------------SLSCHETSSQKLFECILCGRFSCDTLEELSQHLTMQRS----LPSSYWRSTTGDTHHCRLCHYATPLRANFQLHCQTDKHVQRYQLAAHLREASSQQGNIEEEEEEWRLRCVAAGSQVQLRCNACDYKASSLEKLKLHTMNTRHETSLRLYKYLQ------QLDG-LESED-VWLHCVLCDFSTQSSLSLVQHSHSLSHQRGEGLLRLQRIQKGLQDEEE-LGAIFTIRKSPAQENGDMN------------------------GMDSPTEVSANQEDGNKHGELMGK-------KSEGIIETEAEQNESSSSPKRPSSGSEESDEASPCKQPR-----MQEEMRQCPFCRFRHNDIERLRSHVMNQHAVQPSLRCPLCQDTLHSIALLRTHLTHLHSVTADCTQKLINTVIASDVLP-EKMFLPVHNSDTQP-------INANEAKRLDDEITADAEPERGTTPHLEASKIYKQPSEDAESTKENNAAFPCWHKGCNKVFTSSSALQTHFNQIHSQKSQTAISDRHIYKYRCNQCSLAFKTPEKLQLHSQYHAIRAATMCCLCQRSFRTMQALRKHLETSHLELSEAQIQQLYGGLMMNGESLISGDQTFGEEEGSSEEGGLKDEEECDLEEKLSPTDNDSIVVKDNVECDSKQPVLPLRKGPNITMEKFLDPSRPFKCTVCKESFTQKNILLVHYNSVSHLHKLKRSLQDTPTGLQ-----EPVTN-TDNKPFKCSICNVAYSQSSTLEIHMRSVLHQTKARASKVDSSTSSE----SVGPPPGKALSSTPVSMKSATP-----------------------MNNGGLSHQQNTDLNGTPANPDTSHPSTSDVRKKLVTMIDSASKQQQVSLQQQQQQS-----LQQQQQQLAQAQAHLQQELQKKAALLQSHLFNPALLHPFPMATEALLPVQQQQQLLLPFLIPGGEFRMNPEVSLKGSGLNLSTIMP-----TVNQDITEASKN-----DGAKYTSKQKQNEDLAIHPEITEQKLR---------------------------SDSQCENDKDGQKSNERSTEIDNVGANEKPPPKTNENED--LNKNKSTSSDEFLPPRISHDAPGNASKALLENFGFEIVMQFNENRQRYQKNLTEPIPNVG-DVPDTKEVDHSEDVEKLECKSCRKLFSNALILKSHKEQIHHSIFPIKSLEKFAKDYREQYDKLFPLRPTTPEDSPVTSPSPSPPVIPNPSVQQPQQPVQPIIAPSTLSATPTTVSIP--------------QVKTPLAQISIPMELPLFPPLLMPPIPLQALTPPVPVHLPPVDAGLTPDLTQLYQQQL--TPAMLQQ-QSKRPRTRITDDQLRVLRQYFDINNSPNEDQIHEMANKSGLPHKVIKHWFRNTLFKERQRNKDSPYNFSNPPITTLDDVKVDSRPPSPELPRQEFYGGKRSSRTRFNDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLSTRVIVVWFQNARQKARKNYENQGEGGKESERRDLSNDRYFRTSNNNFQCKKCNIVFQRIFDLINHQKKQCYKDDDEELQN-SLNETAGEYQESLSPISGPSCLTQATSCSSPSSSS------VSSTNVKATDSEHKNTTSVYGELKQTNETSSEPKQAVSINCEFKDTENRMQQPKPLCE------------ENQSISTEIQSHSSPKQQKISCTASETNPAPSQSSQKIFSPLETPVSEQQQQQKLSQDMSPYNCIQCKLSFPSFEHWQEHQQMHFLTQS-YFPTPPFLDRSVDMPLMLFDPANPLLARHLLSGTLSQMVANPPAVTSIT-DSTINSLKRKLEEKAGSSSVENDWE--NNGDEPHRDKRMRTTITPEQLEVLYQKYLLDSNPTRKMLDHISNEVGLKKRVVQVWFQNTRARERKGQFRALGPSQIHRRCPFCRALFKAQTALAAHIRSRHWHEARNAGYSMAMSSMGHEQEGSPVKS-----DLFDFATYSQYLNSTDDADSLACKSIDLSSHQQR---LSPKPIKGECMEEFEMPSMS-VYQTFEQSKLN---SHEANTNTTHDHTNDEGNDSLEA---------------QHGSIEHMSPSTEREASSESDEKMSSGLVSPAMSFNAKDLDNEL----------FLDYSENSSLADPASPCP-GSSNSQNFD---YDRHNQKRYRTQMSNLQVKVLKACFSDYKTPTMLECEALGNDIGLAKRVVQVWFQNARAKEKKAKLS---LAKQFGTESTSIDRPKTECTLCSVKYSSSLSIRDHVFSQQHLAKVKEALGGQMERDREYLGSVSTRQLMAQQELEQLKKTSDVLGHVQP---QAILGLNQTALHCLSQSSMYSGLQAQCIANTP-SGSSTMTAGVSSIKTEGASDPP--VKEATHKPTTAATSAISALDDKDVVSTTNPVLTP-----------KTKEQELQ------------------------------LPKENDKESNRIPTNKTDSTPLGNATHSSKEKSDSSRTTVSTPNPGREYAMDPAQLQALHAAMKTDQASLLTSPLLPCLMPGFPPLFSPHIPT-PMPGGLLQPMFGMDS-MFPYGPVLPQALMGLNPSTILQQYQQNLQGALMQQRLQLQQKQIVQLPEK------------------------------PKPSQISA--------RPHAEDTVSSKRDKKQGTSNG----------------------TDSLFMNSVISKQPDLDNNVLLSHCIVSKTECRTEGKDGH-----------------------------------LYDCLACEVSLTGNAELIKHLEFPQHRQRVAERL--NAKEHASPRLPHISPSSTSQPNPSSKQRSSSTAQSS-LATPPETSIPTP-------------------------TSSDQTVRLLQSSPLTSALPEASQSSPAHVVSPSNVTSSLTSLAKTCHMKPIDSVDGHCDGNESEK-----------------GQDST----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZF41-1", "uniprot_id": "D3ZF41_RAT", "id": "D3ZF41-1", "name": "", "aln": "MATLSSVSSSGTIPSPG--------HHVPSPSPETSSSST-SDPVTKDPP-----------------DAPSTAESIRSSEPGGEHLESG--------RDLAPPKEIGEP--------------------------------------RHEPGCGPIPPKDLGVSK------EEKGILPLDLSNHLLFSAGGQAYLLANLSLSGGSELLLPKG-----------FPWDEASVKEEPSLPLLAHFPSSHLTTLHIQHGFDPVQG---------------FSSSDQILSHDTSAPSLAACEGRDGSFWSYQLVPNPTEDPKDGP-MGSRRGDHRAMFWICLLCRLGFGRLQAFIGHTLSHGVKLTPAHHQGLLGS---PAVLQEGHDGGMAFLSFLEPKLLTH----------------------------------------------------------PSPEVP--DTSTVTVKTNGAQAEDGPPEADVQALVLPGEEVMALSPPSPPTALATWDPSPTQAKESPVSRGEAGPDWFPEGQEEDGGLCLPLNQSSPTS----------------------------------------------------------------------------------------------------------------------------KEVAVLPAPAGSPEDTSDPPQSCRLTDDYTP-----------------------------------------------APAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES-NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGP---------GGQASPPEASLPPP-----------------------------------------------SIGEKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLVGPGPPPPPG------------AAPTNPPELFQYFGPQALGQPQTSMPGPGLRPDKPLEAQLLLNGFHHLGAP--ARKFPTAAPGSLSPETHLPPSQLLGSSSDGLS--TSPSPDDSPPLKVFRCLVCQAFSTDSLELLLYHCSIGRT----LPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTDKHTQKYQLAAHLREGGGAMGSPSPLSLGDGTSYGGSVSPLHLRCNICDFESNSKEKMQLHARGSAHEENSQIYKFLL------EMEGAEAGPEPGLYHCLLCAWDTPSRLAVLQHLRMPAHRDAQAQRRLQLLQSGP-AAEEGLSALQSILSFSRGRLQTPG--------------------------KAPDTPLAQPPTSEKDAQN-----------------------RTEQRASEVTEDRTGPPRDSANQITVRTGVTGMMKVFCCPYCSFLSPECDQVRVHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVATTVEMTFATKMLPGP---------------TLNPVEDGLERPAPGPEPTPNRDQVADSSNLAPEASPDPPPPPEPPLAPVEGPME----------------------------------------------------------------------------------PSESPQQPPSPASSPVPRPDAQVEELTPLPTMSEEEEGVMGEP-----------------------RSAEPSPADSRH-LTYRKTTNFALDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSCPARGEAGIPPPTTTASDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGAKTDARTEGP-------------------------------------------------------------------------ERSQEELKEGETEGEVGTEKK-----------------GPDPSGFMSGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQ-QLLLPFYLHDLKVGPKLALASPTPMLSLPAANP-------------------------------------------------------------------------------------------------PPLPAPPKAELAEQEWERPLIAEEGTEAGPSSPPHSSPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTP------------PPPESLGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPPVEPPKPPDGSLESP-PQLGPPFVVPEPEVGGIHTS--------------------------------------------------------------------------------------------------------------------------------------------------------EERGLAGG-PWPSEE-------------EEGSRG---SVVPVGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGPMTAGGATGGASG------------CRRCHATFACVFELVRHLKKCFDDQPPAEEEE-AERGE-------------------------------------EEEEVEEEEVEERNPEPAG-RHGDRSPERANAEDVGQAEPTRPESKETEGKAPPSP------------------------------------------------------------------------PAHTCDQCSISFPSQDLLTTHHRLHFLPSVQPSAP----SQLLDLPLLVFGERNPVVS-------------GPSSVTGTP-------LKRKHDDGSLSPTGSEAGG--GGEGEPPKDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGG----------------VAGPAAKPTATPSPAPFPKFNLLLSKIEDETGKEAPKR---------------------EAPAFPYPTVTPAAAPGPLPFLAPGKEVTAPTPEPPPP-LPPSALSEDEGPEEPSKASPESEACSPSAG-------------------------------------------------------------------------------DLSDSSASSLAEPESPGAGGNGGGPGSGPGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAPAGSGGGSEGPSAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPETPLAPKGPPATTPAS-VPLGAS-----------------------PTLPRLAPVLLPGPTLAQPPLGSIASFNSGPAASS-GLLGLATSVLPATTVVQTAGPGRPLPQRPVS-----------------------------------------------------------NQTNSS----TDPSPGPATEPSGDKVSGERKPVATLTNSSTDALKN-------LKALKATVPALLGGQFLPFPLPPAGGAAPPAVFGPQLQGSYFQQLYGMKKGLFPMNPVIPQTLIGLLPNALLQQPPQAPEP---------------------------------------------------TATAPPK-----PPELPAPGEGESSEADELLTGSAG-------------------------ISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPAPLRVPIC--------------------TYHCLACEVLLSGREALASHLRSSAHRRKAAPPPGGPPITVTN---------------------------------------------------------------------------------------------------SATAVPAAVAFAKEEARLPHTDPNPQTTTTSTLLAL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2MHN3-1", "uniprot_id": "ZFHX2_MOUSE", "id": "Q2MHN3-1", "name": "Zinc finger homeobox protein 2", "aln": "MATLNSASPSGTVPSPG--------HNVRSPPPETSSSST-SDPVTKDPP-----------------DAPSTSESIRSSEPGGERLESG--------SDLDPPKEIGEP--------------------------------------QEEPGCGHIPPKDLGVAK------EEEEILPLDLSSHLFFAAGGQAYLLANLPLPRGSELSLPKG-----------FPWDEASAKEEPSLPLLTHFPSSHLTTLHIQHGFDPIQG---------------FSSSDQMLSHDTSAPSLAACERRDGSFWSYQLVPNPTEDPKDGP-LGSRREDHRAMFWICLLCRLGFGRLQTFIGHTLSHGVKLSPAHHQGLLGS---PAVLQEGHDGGMALLSFLEPKFLTR----------------------------------------------------------PSPEVP--DTSTVTVKTNGAQAEDGPPEADGQALVLPAEEVIALSPPSPPTALATWDPSPTQAKDSPVPRGEAGPDWFPEGQEEDGGLCLPLNQSSPTS----------------------------------------------------------------------------------------------------------------------------KEVAVLPAPAGSPEDTSDPPPSCRLADDYTP-----------------------------------------------APAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES-NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGP---------GGQASPPEASLPPT-----------------------------------------------SVGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLVGPGPPPPPG------------AAPTNPPELFQYFGPQALGQPQTPMPGPGLRPDKPLEAQLLLNGFHHLGAP--ARKFPTAAPGSLSPETHLPPSQLLGSSSDGLP--TSPSPDDSPALKVFRCLVCQAFSTDSLELLLYHCSIGRS----LPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTDKHTQKYQLAAHLREGGGAMGTPSLLALGDGASYG-SISPLHLRCNICDFESNSKEKMQLHTRGSAHEENSQIYKFLL------EMEGAEAGPEPGLYHCLLCAWDTPSRLALLQHLRTPAHRDAQAQRRLQLLQNGP-AAEEGLSALQSILSFSHGRLQTPG--------------------------KASDTPLAQPPTSEKDAQN-----------------------KTEQQASEVTEDRSGPPRDSANQITV----------FCCPYCSFLSPECDQVRVHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVATTVEMTFATKMLPGP---------------TLNPVEDGLDHPAPGAEPTPNRDQVAESSNLAPEVSPDPP--LEPPLAPVEGSRE----------------------------------------------------------------------------------PSESPDQPPSPAPSPAPRLDAQVEELAPLPTMSEEEEGAMGEP-----------------------RSAEPTPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSGPARGEAGIPPPAATASDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGAKIDARAEGA-------------------------------------------------------------------------ERGQEEFKEGETEGEAGTEKK-----------------GPDPGGFMSGLPFLSPPPPPLDLHRFSAPLFTPPVLPPFPLVPESLLKLQQQ-QLLLPFYLHDLKVGPKLALASPTPMLSLPAANP-------------------------------------------------------------------------------------------------PPLPAPPKAELAEQEWERPLMAEEGTEAGPSSPTHTSPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTP------------PPPESLGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPPVEPPKPPDGCLESP-PQLGPPFVVPEPEVGGIHTS--------------------------------------------------------------------------------------------------------------------------------------------------------EERSLSGGGPWPSEE-------------EEGSRGSLPPAVPVGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGPVTAGGASGGASG------------CRRCHATFACVFELVRHLKKCYDDQPPEEEEE-AERGE-------------------------------------EEEEVEEEEAEERNLEPAAARPGGPSPEHADGEDLSQTEPTRPESKESEGKAPPSP------------------------------------------------------------------------PVYACDQCAASFPSQDLLTTHHRLHLLPSVQPSAPP--PSQLLDLPLLVFGERNPVVS-------------GTSSVTGTP-------LKRKHDDGSLSPTGSEAGG--GGEGEPPKDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGG----------------VAGPAVKPTVPPSPAPFPKFNLLLSKIEDETGKEAPKR---------------------DAPAFPYPTVTPAVGP--LPFLPPGKEAAVPTPEPPPP-LPPPALSEDEGPEEPSKASPESEACSPSAG-------------------------------------------------------------------------------DLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDSMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAPPGSGGSSEGTSAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPETPLAPKGPPATTPASSVPLGAS-----------------------PTLPRLAPVLLPGPTLAQPPLGSIASFNSGPAASS-GLLGLATSVLPATTVVQTAGPGRPLPQRPVS-----------------------------------------------------------NQTNSS----TDPTPGPATEPSGDKVSGERKPVATLPNSSTDALKN-------LKALKATVPALLGGQFLPFPLPPAGGAAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPVIPQTLIGLLPNALLQQPPQAPEP---------------------------------------------------TATAPPK-----PPELPASGEGESSEADELLTGSTG-------------------------ISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGASMPAPLRVPIC--------------------TYHCLACEVLLSGREALASHLRSSAHRRKAAPPPGGPPITVTN---------------------------------------------------------------------------------------------------SATAVPAAVAFAKEEARLPHTDPNPKTTTTSTLLAL------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0A1-1", "uniprot_id": "ZFHX2_HUMAN", "id": "Q9C0A1-1", "name": "Zinc finger homeobox protein 2", "aln": "MATLNSASTTGTTPSPG--------HNAPSLPSDTFSSSTPSDPVTKDPP-----------------AASSTSENMRSSEPGGQLLESG--------CGLVPPKEIGEP--------------------------------------QEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSLPGGSELLLPKG-----------FPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG---------------FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGP-MGNSGGNHVAVFWLCLLCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGS---PAVLQEGDEGCKALISFLEPKLPAR----------------------------------------------------------PSSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPT--ATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTS----------------------------------------------------------------------------------------------------------------------------KEGGTLPAPVGSPEDPSDPPQPYRLADDYTP-----------------------------------------------APAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES-NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGP---------GGQGSPPEASLPP------------------------------------------------SAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPG------------ATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAP--ARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLP--TSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRS----LPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYG-SVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKFLL------DMEGAEAGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGP-TTEEGLAALQSILSFSHGQLRTPG--------------------------KAPVTPLAEPPTPEKDAQN-----------------------KTEQLASEETENKTGPSRDSANQTTV----------YCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVATTVEMTFTTKVLSAP---------------TLSPLDNGQEPPTHGPEPTPSRDQAAEGPNLTPEASPDPLP--EPPLASVEVPDK----------------------------------------------------------------------------------PSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGEL-----------------------RSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGP-------------------------------------------------------------------------ERSQEEPKEGETEGEVGTEKK-----------------GPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQ-QLLLPFYLHDLKVGPKLTLAGPAPVLSLPAATP-------------------------------------------------------------------------------------------------PPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTP------------PPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAP--------------------------------------------------------------------------------------------------------------------------------------------------------EERSRAGG-HWPIEE-------------EESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASG------------CRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGE-------------------------------------EEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPS-----------------------------------------------------------------------PAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAP----PQLLDLPLLVFGERNPLVA-------------ATSPMPGPP-------LKRKHEDGSLSPTGSEAGG--GGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGG----------------VPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKR---------------------EAPAFPYPTATLASGP--QPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAG-------------------------------------------------------------------------------DLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPAS-MPLGAA-----------------------PTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASS-GLLGLATSVLPTTTVVQTAGPGRPLPQRPMP-----------------------------------------------------------DQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKN-------LKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEP---------------------------------------------------TATAPPK-----PPELPAPGEGEAGEVDELLTGSTG-------------------------ISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPIC--------------------TYHCLACEVLLSGREALASHLRSSAHRRKAAPPQGGPPISITN---------------------------------------------------------------------------------------------------AATAASAAVAFAKEEARLPHTDSNPKTTTTSTLLAL------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28167-1", "uniprot_id": "ZFH2_DROME", "id": "P28167-1", "name": "Zinc finger protein 2", "aln": "MSSFDVETFNGK-----------IVYNLDGSAHIIATDNTNGGGSGSGQN----------------CYGSTTNSLKNLSKDKGRGQEEK---------DIEHPSQYHRE----------------------------------------QSDNKRQEEAVDNRPGVESLGSACYKSSPKIHSFRVVSAQDANSTCQDQIRAFKIQKPILMCFICKLSFGNVKSFSLHANTEHRLNLEELDQQLLNREYSSAIIQRNMDEKPQ--ISFLQPLANNDASADTNDTEKLQTATEGSDATLPSSPQPVFRNVSELEPENKQETEQNRLLNQDREQEPESDQHTSSSKMAAPSAYIPLSSPKVAGKLTVKFGSLNSATAKTNNLSKVSSTSSPPSTYASGEVLSPSTDNISN--------------------------------------------HKSTHCNQETEPPSSSSSEVEMKIGSMSTSPQTNDSDVPCSGFLQMQHMTTGGAYTPQVSSFHASLAALAANESNDNRVKLITEFLQQQLQQHQSSLFPSPCPDHP-------------------------------------------DLNGVDCKTCELLDIQQRSKSPSSSHHQFS--------QSLPQLQIQSQPQQ------------TPHRSPCSNSVALPVSPSASSVASVGNASTATSSFTIGACSEHINGRP---------------------------------------QGVDCARCEMLLNSARLNSG--VQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDG-ESACGYCLAGQQHPRLARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNMVAAAAAAAVTGKLLLSSSSPQVTAACPSNSGSGAGSGSSNIVGGTASLSGNATPSVTGANSSNANAGSNTNNAGTKPKPSFRCDICSYDTSVARNLRIHMTSEKHTHNMAVLQNNIKHIQAFNFLQQQQQSGTGNIASHSSGSFMPEVALADLAYNQALMIQLLHQQQQHQQSANTKLSPSSSPVSTPDQFSFSPKP-IKLNHGTGAAMGIGMAMGMGMSHSNEVSCELSGDPHPLTKTDKWPMAFYSCLVCDCYSTNNLDDLNQHLLLDRSRQSSSASSEIMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNFINHIREGG-----PQNEYKMQYQQQQLAANVVQLKCNCCDFHTNSIQKLSLHTQQMRHDTMRMIFQHLLYIVQQSEMHN-----------KSSGSAEDDPQCACPDEDQQLQLQSSKKLLLCQLCNFTAQNIHEMVQHVKGIRHLQVEQFICLQ-------------------------RRSENQEIPALNEVFKVTEWVME-------NEDVSLAPGLNLARTTTNDATTDASYAAASSAAVPAIPDVSMFSPTSPSSCATSCDKNLSQIVLPNVNNLGSGVPTTVFKCNLCEYFVQSKSEIAAHIETEHSCAESDEFITIPTNTAALQAFQTAVAAAALAAVHQRCAVIN-PPTQDTVDEDKDLDTNVSDGPVGIKQERLEQEVDRTTSMDVTKDLASQATDFGAPES-----------------------------------------------------PKVAETEVGVQCPLCLENHFREKQYLEDHLTSVHSVTRDGLSRLLLLVDQKALKKESTDIACPTDKAPYANT---------------------NALERAPTPIENTCNVSLIKSTSANPSQSVSLQG-LSCQQCEASFKHEEQLLKHAQQNQHFSLQNGEYLCLAASHIS-------------RPCFMTFRTIPTMISHFQDLHMSLIISERHVYKYRCKQCSLAF------------------------------------------------------------------------------KTQEKLTTHMLYHSMR------------------DATKCSFCQRNFRSTQALQKHMEQAHAEDGTPSTRTNSPQT--PMLSTEETHKHLLAESHAVEREVSGSDVSPIELETHLNKETR---------------------------------------------------------------------------------------------HLSPTPMSLDSQSHQKHLATFAALLKQQQCNSDAGGLHPEALSMSTGEMPPQLQGLQNLQHIQQHFGAVAAAAGLPIN--------------PVDMLNIMQFHHLMSLNFMNLAPPLVFGANAAGNAVSGPSALNNSITTSTATSASGLGDTHLTSGVSSIPVDSGKATAVPPQTQLNANANSQQLAS------------------------------------------------------------------------------------------------NQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGQAKVTPLNDTCSVAVTGPMTSSTISLPPSGNINLSSKENATSKVLAAGKANASGPVTFSATVPVSTPLSRPESTNSSGNISDYIGNNIFFGQLGSKEQILPYSLDGQIKSEPQDDMIGATDFAYQTKQHSSFSFLKQQQDLVDP---------------------------------PEQCLTNQNADTAQDQSLLAGSSLASNCQSQQQINIFETKSESGSSDVLSRPPSPNS----------------------------------------------------------------------------GAAGNVYGSMNDLLNQQLENMGSNMGPPKKMQIVGKTFEKNVAPMVTSG--------------------------------SVSTQFESNSSNSSSSSSST-------SGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRK--IYENQPNNTLFENEETKKQNINYACKKCNLVFQRYYELIRHQKNHCFKEENNKKSAKAQIA------------AAQIAQNLSSEDSNSSMDIHHVGICPPGSAVASHTLSTPGSAAPLPGQYTQHSFGALPSPQHLFAKSSSLTDFSPSTTPTPPQRERSN---------------------------------------SLDQIQRPPKFDCDKCELNFN---------QLEKLREHQLLHLMNPGNICSDVGQNSN----PEANFGPFGSILQSLQQAAAQQQQQHHQQPPTKKRKYSDCSSNADEMQSLSELEASQKKHEYLYKYFMQNETSQEVKQQFLMQQQQKKLEQGNECDFELDFLTNFYQQNELKKVSNYDFLLQYYRTHEEAKSSQQHTFSSSKKPTIEFLLQYYQLNES----------KKFFQLVASPQIIPDVPGYKPSLRIPKSTSDEAPYIGETSLEQATELQREKQDEQLRIDRPSEENDLSMNKNKVENINNNNINVDQSNLTETNGGVPSVETKEECTQ--------------------------ESSLIAMDDENKYLCTRSKQKDDKEKSHYLHNLEDFLDATMIENNSQTLTFNDDEKACQKDELTQNSNAIEKRSSVSPVNVSSKQNKRLRTTILPEQLNFLYECYQSES--NPSRKMLEEISKKVNLKKRVVQVWFQNSR--------------------------------------------------AKDKKSRNQRHYAHISDDNSYDGSSGKEVYSDLRSNG--------------------------ITVDTDLETNLQDCQLCQVTQVNIRKHAFSVEHISKMKKLLEQTTELYAQS----------------------NGSGSEDNDSDREKRFYNLSKAFLLQHVVTNATSHAIHTAR-------------------QDSDVIAEGN--------------------------------------------------------------------CILNYDTNGGDSKSHVQHNLPNEVVSEDARKIAGNQELMQQLFNRNHITVIGGK--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. ...: . : * . . : . . :. :: : . . : . :. . : . : . . :: . .. . :**********:********:**: **:****: * ** :* ********:*. ****:**::*:******************* *:* :: . . : :.: :*.:*.*:*.::************ :*: :*::.: : * . .: * :* :: :.*: * * *: .. .: : *:** * * *:****** :**** *: :: *::*.. . ::*:** **: :.* :*: :*: *: :::.* . .. :. : : : * : .: : : : . * . . * : . : : . . * **: : . : *: *. . : . : : . : . : . :. * .. .: :. .* *: **.::: ** * :. .*: : . :* . :. * ::** :: : : : . . . . .* * . .:* :: : *:. . : : . * .:: : *. :: . :::. * : *.. . . :** . : . . . . .: :. .:. .. . .. . . : :* : . . ::: . . . : . : : : :: :: . : .: : . :. : :. . .: ** : *:::* : :* *. . *: ::. : *. **: *****:* ::** : . . . : . . : . .: . .* . : : : .** : . :: *. : : . . . : :: :: *.. .. : . . : :. :.:.::.: *: : . . . : . . : . .. . . . . . : : :: :. : . * : . : : . . : : . . : . : .: . ..: . :* . .:. . . : : * . ", "identical_positions": 181, "similar_positions": 399, "identity": "4.38%" }, { "cls_id": "homologset.agr.FB:FBgn0004611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51432-1", "uniprot_id": "PLCB3_MOUSE", "id": "P51432-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "aln": "MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYAR--LPKDPKIREVLGFGGPDTRLEEKLMTVVA-GPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS---ADKKRVETALESCGLNFNRSESIRPDEFPLEIFERFLNKLCLRPDIDKILLEIGAKGK----------------------PYLTLEQLMDFINQKQRDPR--LNEVLYP-PLRSSQARLLIEKYETNKQFLERDQMSMEGFSRYLGGEENGILP-------------LEALDLSMD-------------------MTQPLSAYFINSSHNTYLTAGQLAGPSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAEAAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIDPLDKYPLSAGIPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVRKRPLEQ----SNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEESLSREPNVPMPDRDREDEEEDEEEEETTDPKKPTTD---------EGTASSEVNATEEMSTLVNYVEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSP-MEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDKKVGIYVEVDMFGLPVDTRRK-YRTRTS-QGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQET--------------------PCQQPGSQLPSNPTPNPLDASPRWPPGP--------------TTSSTSSSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALT-----------------RRLLDGLAQARAEGKCRPSPS---------ALGKATNSEDVKEEEE--AKQYREFQNRQVQSLLELREAQADVETKRKLEHLRQAHQRLKEVVLDT-HTTQFKRLKELNEREKKELQKILDRKRNNSISEAK--TREKHKKEVELTEINRRHITESVNSIRRLEEAQKQRHERLVAGQQQVLQQLEEEEPKLLAQLTQECQEQ----RERLPQEIRR----CLLGETAEGLGDG----PLVACASNGHAPGSGGHLSSADSESQEENTQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99JE6-1", "uniprot_id": "PLCB3_RAT", "id": "Q99JE6-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "aln": "MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRLDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYAR--LPKDPKIREVLGFGGPDTRLEEKLMTVVA-GPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNAP-EHVLRKAYTKLKLQVNQDGRIPVKNILKMFS---ADKKRVETALI-CGLNFNRSESIRPDEFSLEIFERFLNKLLLRPDIDKILLEIGAKGK----------------------PYLTLEQLMDFINQKQRDPR--LNEVLYP-PLRSSQARLLIEKYEPNKQFLERDQMSMEGFSRYLGGEENGILP-------------LEALDLSMD-------------------MTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGEALLIDPLDKYPLSAGTPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVAKRPLEQ----SNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEEGLNRGPNVLMPDRDREDEEEDEEEEETTDPKKPTTD---------EGTASSEVNATEEMSTLVNYVEPVKFKSFEASRKRNKCFEMSSFVETKAMEQLTKSP-MEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRK-YRTRTS-QGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGRFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTEMCQET--------------------PSQQQGSQLSSNPVPNPLDDSPRWPPGP--------------TTSPTSTSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALT-----------------RRLLDGLAQARAEGKCRPSSS---------ALSRATNVEDVKEEEKEAARQYREFQNRQVQSLLELREAQADAETERRLEHLKQAQQRLREVVLDA-HTTQFKRLKELNEREKKELQKILDRKRNNSISEAK--TREKHKKEVELTEINRRHITESVNSIRRLEEAQKQRHERLLAGQQQVLQQLVEEEPKLVAQLTQECQEQ----RERLPQEIRR----CLLGETSEGLGDG----PLVACASNGHAAGSGGHQSGADSESQEENTQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01970-1", "uniprot_id": "PLCB3_HUMAN", "id": "Q01970-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "aln": "MAGAQPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYAR--LPKDPKIREVLGFGGPDARLEEKLMTVVS-GPDPVNTVFLNFMAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS---ADKKRVETALESCGLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGK----------------------PYLTLEQLMDFINQKQRDPR--LNEVLYP-PLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYLGGEENGILP-------------LEALDLSTD-------------------MTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSAGGPDSAGRKRPLEQ----SNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGDEGLNRGPYVLGP-ADREDEEEDEEEEEQTDPKKPTTD---------EGTASSEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSP-MEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRK-YRTRTS-QGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGQETCQDT--------------------QSQQLGSQPSSNPTPSPLDASPRRPPGP--------------TTSPASTSLSSPGQRDDLIASILSEVAPTPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVTLT-----------------RRLLDGLAQAQAEGRCRLRPG---------ALGGAADVEDTKEGEDE-AKRYQEFQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDA-NTTQFKRLKEMNEREKKELQKILDRKRHNSISEAK--MRDKHKKEAELTEINRRHITESVNSIRRLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQ----RARLPQEIRR----SLLGEMPEGLGDG----PLVACASNGHAPGSSGHLSGADSESQEENTQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z1B3-1", "uniprot_id": "PLCB1_MOUSE", "id": "Q9Z1B3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "aln": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAK--APKDPKLRELLDVGN-IGHLEQRMITVVY-GPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFS---ADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSK----------------------PYLTVDQMMDFINLKQRDPR--LNEILYP-PLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVS-------------PEKLDLNED-------------------MSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSS---EGSGKKKLSEQ----ASNTYSDSSSVFEPSSPGAG-----------------------------------------------EADTESDDDDDDDDCKKSSMD---------EGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSP-VEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTS-QGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGE--------------------TSSEAPSETRTTPAENGVNHTASLAPKPPSQA---------PHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSP---------DHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC-QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDK----FKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLASDAAKVNLKSPSSEEIERENPGREFDTPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10687-1", "uniprot_id": "PLCB1_RAT", "id": "P10687-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "aln": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAK--APKDPKLRELLDVGN-IGHLEQRMITVVY-GPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFS---ADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSK----------------------PYLTVDQMMDFINLKQRDPR--LNEILYP-PLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVS-------------PEKLDLNED-------------------MSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSS---EGSGKKKLSEQ----ASNTYSDSSSVFEPSSPGAG-----------------------------------------------EADTESDDDDDDDDCKKSSMD---------EGTAGSEAMATEEMSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKGLEQLTKSP-VEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTS-QGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGE--------------------TSSEAPSETRTTPAENGVNHTATLAPKPPSQA---------PHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSP---------DHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC-QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMELEQEYQDK----FKRLPLEILEFVQEAMKGKVSEDSNHGSAPPSLASDPAKVNLKSPSSEEVQGENAGREFDTPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQ66-1", "uniprot_id": "PLCB1_HUMAN", "id": "Q9NQ66-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "aln": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAK--APKDPKLRELLDVGN-IGRLEQRMITVVY-GPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFS---ADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSK----------------------PYLTVDQMMDFINLKQRDPR--LNEILYP-PLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVS-------------PEKLDLNED-------------------MSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSS---EGSGKKKLSEQ----ASNTYSDSSSMFEPSSPGAG-----------------------------------------------EADTESDDDDDDDDCKKSSMD---------EGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSP-VEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTS-QGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGE--------------------TPSEAPSEARTTPAENGVNHTTTLTPKPPSQA---------LHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSP---------DHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC-QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDK----FKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KGF7-1", "uniprot_id": "PLCB2_MOUSE", "id": "A3KGF7-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "MSLLNP-----VLLPPNVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTYQNQEMEFLDVTSIRDTRFGKFAK--IPKSQKLREVFNMDFPDNHFLLKTLTVVS-GPDMVDLTFYNFVSYKENVGKDWAEDVLALAKHPMTVNAPRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFP---ADRKRVEAALGACHLAKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHSKAK----------------------PYMTKEHLTKFINQKQRDPR--LNSLLFP-PARPEQVQVLIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLA-------------HDTLLIHQD-------------------MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRSMFGETLLTDPLENFPLKPGIPLPSPEDLRGKILIKNKKNQFSGP----ASPSKKPGGV----AEGSLPSSVPVEEDTGWTAEDRTEVEE-----------------------------------EEVVEEEEEEESGNLDEEEIKKMQSD---------EGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYVVSSFTELKAYELLSKAS-MQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRLDKQFNPFSVDRIDVVVATTLSITIISGQFLSERSVRTYVEVELFGLPGDPKRR-YRTKLSPTANSINPVWKEEPFIFEKILMPELASLRIAVMEEGSKFLGHRIIPINALHSGYHHLCLRSESNMALTMPALFVFLEMKDYIPDTWADLTVALANPIKYFNAQDKKSVKLKGVTG-----------------------------------SLPEKLFS-GTPVASQSNGAP--------------------VSAGNGSTAPGTKATGEEATKEVTEPQTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQT----QAAG----CKLRPGKGSRKKRT---------LPCEETV-VAPSEPHDRADPRVQELKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK-QAAELKTFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEERQTACLEQIQAMEKQFQEKALAEYEAK----MKGLEAEVKESVRAYFKDCFPTEAEDK------PERSCEASEESCPQEPLVSKADTQE--SRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89040-1", "uniprot_id": "PLCB2_RAT", "id": "O89040-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "MSLLNP-----VLLPPKVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTHQSKEMEFLDVTSIRDTRFGKFAK--IPKSQKLREVFNMDFPDNHFLLKTFTVVS-GPDMVGLTFHNFVSYKENVGKDWAEDVLALAKHPMTANASRSTFLDKILVKLKMQLSPEGKIPVKNFFQMFP---ADRKRVEAALSACHLAKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAK----------------------PYMTKEHLTKFINQKQRDPR--LNSLLFP-PARPEQVQALIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLA-------------HDTLRIHQD-------------------MTQPLNHYFINSSHNTYLTAGQFSGPSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAVEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRTMFGETLLTEPLENFPLKPGMPLPSPEDLRGKILIKNKKNQFSGP----ASPNKKPDGV----SEGGFPSSVPVEEDTGWTAEDRTEVEEGE--------------------------------EEEEVEEEEEEESGNLDEEEIKKMQSD---------EGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYLVSSFTELKAYELLSKAS-MQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRQDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRR-YRTKLSPTANSINPVWKEEPFIFEKILVPELASLRIAVMEEGGKFIGHRIIPINALHSGYHHLCLRSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKYFSAHDKKSVKLKEVTG-----------------------------------SLPEKLFS-GIPVASQSNGAP--------------------VSAGNGSTAPGTKAK-EEATKEVAEPQTTSLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQD----PAAS----CKLRPGKGSRKKRI---------VPCEETI-VVPREVLEGPDPRVQDLKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK-QAAELKSFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEEKQTACLEQIQAMEKQFQEKALAEYEAK----MKGLEAEVKESMRACFKACFPTEAEEK------PERPCEASEESCPQEPLVNKTDTQE--SRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00722-1", "uniprot_id": "PLCB2_HUMAN", "id": "Q00722-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "MSLLNP-----VLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDTRFGKFAK--MPKSQKLRDVFNMDFPDNSFLLKTLTVVS-GPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMFP---ADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAK----------------------PYMTKEHLTKFINQKQRDSR--LNSLLFP-PARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLA-------------QDKLLLHHD-------------------MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGP----TSSSKDTGGE----AEGSSPPSAPAGEGTVWAGEEGTELEE------------------------------------EEVEEEEEEESGNLDEEEIKKMQSD---------EGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKAS-VQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRR-YRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMG-----------------------------------GLPEKPFPLASPVASQVNGAL--------------------APTSNGSPAARAGAR-EEAMKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGP----PGVGGVGACKLGPGKGSRKKRS---------LPREESAGAAPGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREK-QAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQFQKEALAEYEAR----MKGLEAEVKESVRACLRTCFPSEAKDK------PERACECPPELCEQDPLIAKADAQE--SRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25455-3", "uniprot_id": "PIP1_DROME", "id": "P25455-3", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II", "aln": "--MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAK--RPKDNKLRQIVTLGP-QDTLEEKTVTVCH-GSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKR---------------------KCMSIAQLVEFLNKTQRDPR--LNEILYP-YANPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMA-------------PSKLDLCDD-------------------MDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGR--TEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCN-PRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMDLPPPAMLRRKIIIKNKKKHHHHH---HHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERP-IEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTV-RDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKDYVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPLDLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKEQPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGE---NGPVVCHGF-LTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVG-------TRTDKLPSPRELKHKILLKSKKTSEATR----GLSVNEPFPS-------SFSSSYESANEQELRMK-----------------------------------------------DDSTNSSSATNSSSMQRIKRIG-----------LKKHADIINDVSNISG-IHGIKFRNFSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQ-----------PDGSFKSGYVLKPKKLLPVVTKAKMIP---------LIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFN----------PIWDAEVSITLKDTDLTFIKFMVISEETQIASVCLKLNYLR------------------------------------------------------------------------------------------------------------MGYRHIPLFNMEGEQYIFCTLFIHTQIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *: . :: . : . : : .. : . . :.::. * * : . . . : : : : : . . :: . . .:: : :: :. .: * . : . * ..:. .: . . * :: :: .*:: : : . ** . : . : : :: .. :.::* :.: :* :: : * : * :*:. *** ******* . *:: .*.* * * * ******:* *.*. : *.: **: :.. : : .:..* : ** ** :*:::*:* : : .*: . : : : **.* * :*::*.** : . : . ... . . .. ::* : . :. :* .*. . .:. .. .* . : :.: .:*: : *:** * .***: * **:.* *:** *:** *: * * .::: :. * :.. . ::. . .::. : ..: . * : *: * .* .: . . . ::* :: . . . . *:. .: . : : .* . . : .: :: : . : : ", "identical_positions": 92, "similar_positions": 234, "identity": "6.62%" }, { "cls_id": "homologset.agr.FB:FBgn0004618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0B1-1", "uniprot_id": "ZN524_MOUSE", "id": "Q9D0B1-1", "name": "Zinc finger protein 524", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MDNPSSDPLP----------------------STLSGEEEKPLALLPPVPR-------------------------------------GRRGRPPGGATTSNRTLKSSLPRKRGRPPRSEQETP---------------------------------------------------------------------------LTAPVDSGGSSDLLLIDDQGVPYTVPEGSAADGPQGSGSK--RAPHFCPVCLRAFPY---LSDLERHSISHS-----------ELKPHVCKDCGKTFKRSSHLRRHCNIHAGLRPFRCVLCPRRFREAGELAHHHRIHSGERPYQCPSCRVRFTEANTLRRHYKRKHPELVGMPVRLCPPNPRTQPLWDDDEGIPVQEGVQEESPEGKEPTWPISSTTSPLSGFTAGGSAGAGRGQEGQDTLVSGGIPTMEGDQKQGPKPLGPGAIGHPPVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13360-1", "uniprot_id": "GLAS_DROME", "id": "P13360-1", "name": "Protein glass", "aln": "MGLLYKGSKLLNTILDSLEDQEGGAMYISCDVSNGGPVEPETGYVPNNPLFGLALDSPQQECAASCVGCLSCQGSTALPISSLTSSDFDCGGCFDPTIGVGVGIGGGHIQISTTPPASSGNGSSNNGAGGGSSGNHGYWSTDEMASTFPGLPPLDIDPLPSLFPFSPCGASYNFAAGNPHQAASLSYTVHPHQMLISPNSHNHGQMHSQHQQHQHQQSQVQASHVGNSLLQSSGGNNIGSNGSAGGVANAASCYYETSAGTAAPPPPPAAAMYPSMSVNVSMNMTMHHGYGAGDAGGVPMQCSQMNWTPPSNSTSAAAAAAAVNVLYPPLLSPGHYPASATYSFTADFRAPAPTGLGALPPLTVGEKESPSPPANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSLSAFEDEEDSNEDLDGDEGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTAHVRTHTGQKPFRCPICDRRFSQSSSVTTHMRTHSGERP-YRCSSCKKSFSDSSTLTKHLRIHSGE----KPYQCKLCLLRFSQSGNLNRHMRVHGNNNSSNG--------SNGATGVGGESSTGSGVGGGNSLLT----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . **** ::** . *:.* .: * .* . * *.::. ::* ** : * .**.. *. . * : :.:. . .. .. *. * * *.: .** .*.. :* . ** :* .. *:. *:**::*: ****: *.* *: * . *:* **:** * : * :*.:*: * * *:*::*::** * **:::.:: * : : * * . .. .. * * :. : * :*.: . : . *. .:..* *.* . : *:.. *. * .:: ", "identical_positions": 78, "similar_positions": 104, "identity": "12.56%" }, { "cls_id": "homologset.agr.FB:FBgn0004619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48058-1", "uniprot_id": "GRIA4_HUMAN", "id": "P48058-1", "name": "Glutamate receptor 4", "aln": "---------MRIISRQIVLLFSGFWGLAMG----AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQ------FVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVS----YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKH-VKGYHYIIANLGFK-DISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TP-------PKYTSALTYDGVLVMAETFRSLRRQKID------ISRRGNAG----------------DCLANP--AAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS-TGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR-------TVVVTTIMESPYVMYKKN--HEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK-IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEP-EDGKEGP-SDQPP--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLR------------------------------------------------------TPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKL-------TFSEAIRNKARLSITGS-------VGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASDLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2W8-1", "uniprot_id": "GRIA4_MOUSE", "id": "Q9Z2W8-1", "name": "Glutamate receptor 4", "aln": "---------MRIICRQIVLLFSGFWGLAMG----AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQ------FVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVS----YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKH-VKGYHYIIANLGFK-DISLERFIHGGANVTGFQLVDFNTPMVTKLMDRWKKLDQREYPGSE-TP-------PKYTSALTYDGVLVMAETFRSLRRQKID------ISRRGNAG----------------DCLANP--AAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS-TGPRKVGYWNDMDKLVLIQDAPTLGNDTAAIENR-------TVVVTTIMESPYVMYKKN--HEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK-IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEP-EDGKEGP-SDQPP--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLR------------------------------------------------------TPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKL-------TFSEAIRNKARLSITGS-------VGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASDLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19493-1", "uniprot_id": "GRIA4_RAT", "id": "P19493-1", "name": "Glutamate receptor 4", "aln": "---------MRIICRQIVLLFSGFWGLAMG----AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQ------FVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVS----YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKH-VKGYHYIIANLGFK-DISLERFIHGGANVTGFQLVDFNTPMVTKLMDRWKKLDQREYPGSE-TP-------PKYTSALTYDGVLVMAETFRSLRRQKID------ISRRGNAG----------------DCLANP--AAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS-TGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIENR-------TVVVTTIMESPYVMYKKN--HEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK-IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEP-EDGKEGP-SDQPP--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSSLG------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKL-------TFSEATRNKARLSITGS-------VGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASDLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z9L8-1", "uniprot_id": "A0A8M6Z9L8_DANRE", "id": "A0A8M6Z9L8-1", "name": "Glutamate receptor", "aln": "--------------MRILVLIPLLWGLGEG----AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNATEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLVTPSFPAEGETQ------FVLQLRPSIRGALLSLLDHYDWSRFVFLYDTDRGYAVLQAIMEKAGQNGWQVSAICVENFNDAS----YRRLLEDLDRRQEKKFVIDLEAERLQNILEQIVSVGKH-VKGYHYIVANLGFK-DISLERFMHGGANVTGFQLVDFSKPMVIKLMQRWNKLDQREYPGSE-SP-------PRYTSSLTYDGVLVMAEAFRNLRRQKID------ISRRGNAG----------------DCLANP--AAPWNQGIDMERTLKQVRIQGLTGNIQFDHYGRRVNYTMDVFELKS-NGPRKIGYWNDLDKLVLVQNELSMGND-SAMENR-------TVIVTTIMEGPYVMLKKN--WEMYEGNEQFEGYCVDLASEIAKHIGIKYKISIVPDGKYGARDPETK-IWNGMVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEP-EEGSDGPPSDQPP--------------------------NEFGIFNSLWFSLGAFMQQGCDFTPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSQLR------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKSSQALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAEAKKLKL-------TFSEAMRNKARLSITGS-------LGENGRVLTPDCPKAVHSGPSYRHGPALAVVSSYLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42263-1", "uniprot_id": "GRIA3_HUMAN", "id": "P42263-1", "name": "Glutamate receptor 3", "aln": "--MARQKKMGQSVLRAVFFLVLGLLGHSHG----GFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQ------FVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQE---FRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-SRGYHYMLANLGFT-DILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAP-------LKYTSALTHDAILVIAEAFRYLRRQRVD------VSRRGSAG----------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKV-SGSRKAGYWNEYERFVPFSDQ-QISNDSASSENR-------TIVVTTILESPYVMYKKN--HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETK-IWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPP--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALR------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKL-------TKNTQNFKPAPATNTQN-------YATYREGYNVYGTESVKI------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19492-1", "uniprot_id": "GRIA3_RAT", "id": "P19492-1", "name": "Glutamate receptor 3", "aln": "--------MGQSVLRAVFFLVLGLLGHSHG----GFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQ------FVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQE---FRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-SRGYHYMLANLGFT-DILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAP-------LKYTSALTHDAILVIAEAFRYLRRQRVD------VSRRGSAG----------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKV-SGSRKAGYWNEYERFVPFSDQ-QISNDSSSSENR-------TIVVTTILESPYVMYKKN--HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETK-IWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPP--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALG------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKL-------TKNTQNFKPAPATNTQN-------YATYREGYNVYGTESVKI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2W9-1", "uniprot_id": "GRIA3_MOUSE", "id": "Q9Z2W9-1", "name": "Glutamate receptor 3", "aln": "--------MGQSVLRAVFFLVLGLLGHSHG----GFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQ------FVIQMRPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQE---FRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-SRGYHYMLANLGFT-DIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAP-------LKYTSALTHDAILVIAEAFRYLRRQRVD------VSRRGSAG----------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKV-SGSRKAGYWNEYERFVPFSDQ-QISNDSSSSENR-------TIVVTTILESPYVMYKKN--HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETK-IWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPP--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALR------------------------------------------------------TPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKL-------TKNTQNFKPAPATNTQN-------YATYREGYNVYGTESVKI------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JH93-1", "uniprot_id": "A0AC58JH93_DANRE", "id": "A0AC58JH93-1", "name": "Glutamate receptor", "aln": "---------MRRRAHASVLLLPWLVLQTQA----GFPNQINIGGLFMRSTVQEHSAFRFAVQLYNTNQNITEKPFHLNYNVDNLESSNSFSVTHAFCSQFSRGVYAIFGFYDRRSMNTLTSFCGALHTSFITPSFPTDTDVQ------FVLQMRPSLRGALLSLLAHYKWEKFVYLYDTDRGFSILQAIMESAVMNNWQVTARSVGNIVDPLE---YRRIIEEMDRRQEKRFLIDCEVERINSILEQVVIAGKN-SRGYHYILANLGFT-NMSLDKVFSGGANITGFQIINPDSPIVQQFLQRWERLDEREFPESRSSP-------LKYTSALTHDAILVIAEAFRYLRRQRVD------ISRRGSAG----------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRSNYTVDVYEMKP-GGARKIGYWNEFEKFVYIVEQ-QVTNESSSVENR-------TIVVTTIMEAPYVMYKRN--YMQLEGNDRYEGYCVDLASEIAKHVGIKYKLSIVADGKYGARDPETK-TWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLDDN-EETKDPQTPPDPP--------------------------NDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRSAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKHKARCPTVSLWLTDIRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGTKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMTVALVEFCYKSHQETKRLKL-------AKNAQNFKPAPPSTAQS-------FTTYREGYNVYGTESVKI------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A286Y9Q6-1", "uniprot_id": "A0A286Y9Q6_DANRE", "id": "A0A286Y9Q6-1", "name": "Glutamate receptor", "aln": "------------MTQSALIFLLWLFGTSLA----GFPNQINIGGLFMRSTVQEHSAFRFAVQLYNTNQNMTEKPFHLNYNVDNLESSNSFSVTHAFCSQFSRGVYAIFGFYDKKSMNTLTSFCGALHTSFVTPSYPIDSDVQ------FVIQMRPPLKGAVLSLLSHYKWDKFVYLYDTDRGFSILQAIMEAAVANNWQVTARSVGSITDPQE---FRRIIEEMDRRQEKRYLIDCEVDRINVILEQVVTLGKN-SRGYHYIIANLGFT-NISLDKVFLGGANISGFQIINPENLVVQQFLQRWDRLDEREFPEAKNTP-------LKYTSALSYDAILVIAEAFRYLRRQRVD------VSRRGSAG----------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRTNYTIDVYEMKT-GGPRKIGYWNEFERFVNIMDQ-QFTNDSSSVENR-------TIVVTTIMEAPYVMYKKN--HMHLEGNEKYEGYCVDLASEIAKHVGIKYRLSIVMDGKYGARDPETK-SWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWQLDET-DEVKDPQTPPDPP--------------------------NDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTTPDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALR------------------------------------------------------TPVNLAVLKLSEQGILAKLKNKWWYDKGECGTKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAEAKRLKL-------EKNAQNYKPAPPANTQN-------FATYREGYNVYGTESVKI------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19491-1", "uniprot_id": "GRIA2_RAT", "id": "P19491-1", "name": "Glutamate receptor 2", "aln": "---------MQKIMHISVLLSPVLWGLIFG----VSSNSIQIGGLFPRGADQEYSAFRVGMVQFST------SEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP------FVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKH-VKGYHYIIANLGFT-DGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTAT-------IKYTSALTYDAVQVMTEAFRNLRKQRIE------ISRRGNAG----------------DCLANP--AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKT-NGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK-------TVVVTTILESPYVMMKKN--HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTK-IWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF--EDGRETQSSEST--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLG------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV-------AKNPQNINPSSSQNSQN-------FATYKEGYNVYGIESVKI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23819-1", "uniprot_id": "GRIA2_MOUSE", "id": "P23819-1", "name": "Glutamate receptor 2", "aln": "---------MQKIMHISVLLSPVLWGLIFG----VSSNSIQIGGLFPRGADQEYSAFRVGMVQFST------SEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP------FVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKH-VKGYHYIIANLGFT-DGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTAT-------IKYTSALTYDAVQVMTEAFRNLRKQRIE------ISRRGNAG----------------DCLANP--AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKT-NGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK-------TVVVTTILESPYVMMKKN--HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTK-IWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF--EDGRETQSSEST--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLG------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV-------AKNAQNINPSSSQNSQN-------FATYKEGYNVYGIESVKI------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42262-1", "uniprot_id": "GRIA2_HUMAN", "id": "P42262-1", "name": "Glutamate receptor 2", "aln": "---------MQKIMHISVLLSPVLWGLIFG----VSSNSIQIGGLFPRGADQEYSAFRVGMVQFST------SEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHP------FVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKH-VKGYHYIIANLGFT-DGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTT-------IKYTSALTYDAVQVMTEAFRNLRKQRIE------ISRRGNAG----------------DCLANP--AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKT-NGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK-------TVVVTTILESPYVMMKKN--HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTK-IWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF--EDGRETQSSEST--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLR------------------------------------------------------NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV-------AKNAQNINPSSSQNSQN-------FATYKEGYNVYGIESVKI------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BI34-1", "uniprot_id": "A0A8M2BI34_DANRE", "id": "A0A8M2BI34-1", "name": "Glutamate receptor", "aln": "-------------MILSGLLLPALWGLALG----GSP-SVQIGGLFPRGADQEYSAFRIGMVQFGT------AEFRLTPHIDNLEVANSFAITNCFCSQFSRGVYAIFGFYDKKSVNTITSFCETLHVSFITPSFPADGLNQ------FVLQMRPDIKGPLISLVEYYKWEKFAYLYDSDRGLSTLQAVLDTAAERKWQVTAINVGNLKDEWKDEAYRSLFQDLENKNERRVILDCEQDKVKDIMEQVITIGRH-VKGYHYIIANFGFV-DGDLSKIQYGGANVSGFQIVDFDDPLVAKFDQRWEALEEKEYPGADSR--------IRYTSALTYDAVQVMTEAFRFLHKQRID------ISRRGNNG----------------DCLANP--AVPWAQGVEIERALKQVRVDGLTGNIQFDQYGRRVNYTVNVMELKN-SGPVKIGYWNEMDKMAVTKSDLFP-NDTMGMENK-------TVIVTTILEAPYVMLKKN--AELFTDNERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGARDAETK-IWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEF--EDG-QLGPSEST--------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDAGSTKEFFRRSKIALFDKMWQYMKSAEPSVFVKNTVEGVLRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALR------------------------------------------------------TPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAEAKRMKMTFTDAMRSKARLSITGSTGENGR--------VLTPDFSKAVHAVPYLRPGMAMPLSVSELS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19490-1", "uniprot_id": "GRIA1_RAT", "id": "P19490-1", "name": "Glutamate receptor 1", "aln": "------------MPYIFAFFCTGFLGAVVGA---NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTE-------PPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ------FVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEG----YRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKN-GIGYHYILANLGFM-DIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKR-------PKYTSALTYDGVKVMAEAFQSLRRQRID------ISRRGNAG----------------DCLANP--AVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH-DGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNR-------TYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK-AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRDQTTSDQ---------------------------SNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALR------------------------------------------------------NPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS-ALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23818-1", "uniprot_id": "GRIA1_MOUSE", "id": "P23818-1", "name": "Glutamate receptor 1", "aln": "------------MPYIFAFFCTGFLGAVVGA---NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTE-------PPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ------FVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEG----YRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKN-GIGYHYILANLGFM-DIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKR-------PKYTSALTYDGVKVMAEAFQSLRRQRID------ISRRGNAG----------------DCLANP--AVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH-DGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNR-------TYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK-AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRDQTTSDQ---------------------------SNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALR------------------------------------------------------GPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTS-ALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42261-1", "uniprot_id": "GRIA1_HUMAN", "id": "P42261-1", "name": "Glutamate receptor 1", "aln": "------------MQHIFAFFCTGFLGAVVGA---NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTE-------PPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ------FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEG----YRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKN-GIGYHYILANLGFM-DIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKR-------PKYTSALTYDGVKVMAEAFQSLRRQRID------ISRRGNAG----------------DCLANP--AVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH-DGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNR-------TYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTK-AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRDQTTSDQ---------------------------SNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALR------------------------------------------------------NPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS-ALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSG-GSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATGL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1V8-1", "uniprot_id": "E7F1V8_DANRE", "id": "E7F1V8-1", "name": "", "aln": "------------MWQSFVLLLTGLLGLCSCS---SFPSNINIGGLFP-TDSHEYDVFRFALSQHND-------VPKLVPQVDMVDTGSSFAMTYAFCSQFSKGVYAIIGLYDRKTMNMLMSFCGALHVCFVTPSFPIDTNNQ------FVIQLRPELQDALIALVEHYKWNKFVYMYSSDSGLTVLQKILDTAAEKTWQVTSINFDTLTEAA----FLKAIQDLDNKKEFKIILDCELERLNSILNLIAAQKKN-LKNYHYILANLGFL-DLNLTEFRKGGANVTGFQLMNYTNPTVSRTIQDWLEFDSKD-LKSPKRR-------LKYTGALTYDGVTVMATAFQNLRKQRID------ISRRGNAG----------------ECLANP--PAPWGQGIDIQRALQQVQFEGLTGHVQFNDKGHRTNFTVSVMEFGP-SGPKKVGYWNQREKYVSTATYSNMLNETFGLQNR-------TYVVTTILEAPYVMLKKN--HEQLVGNDKYEGYCVELAAEIAKHVGYSYRLELVGDGKYGARDAETM-MWNGMVGELVYGKADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHADDE-EETADQQNQNQPPSPEPNQSPNQSQNQREEKQEKQPEHTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDGGSTKEFFRRSKIAVFEKMWSYMKSAEPTVFVKTTDEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALR------------------------------------------------------IPVNLAVLKLNEQAVLDKLKNKWWYDKGECGSKDSARKDKTS-ALSLSNVAGVFYILIGGLGLAMLVALVEFCYKSRIESRRMK-------QIIDAAMLSSTLTRMGSG--------GENGRVMAHDFPKGAQTLPCMGQAAAMGLSTTGM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03445-1", "uniprot_id": "GLR1_DROME", "id": "Q03445-1", "name": "Glutamate receptor 1", "aln": "MHSRLKFLAYLHFICASSIFWPEFSSAQQQQQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHNLN--VSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRSHGGSSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIG---------GATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMN-ANQHHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLR------------------------------------------------------KRLNEAVLTLKENGELLRIRNKWWFDKTECN---LDQETSTPNELSLSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLKSPG------SNGSAGGVPGMLASSTYQRDSLSDAIMHSQAKLAMQASSEYDERLVGVELASNVRYQYSM-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 278, "similar_positions": 261, "identity": "26.05%" }, { "cls_id": "homologset.agr.FB:FBgn0004620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01812-1", "uniprot_id": "GRIK4_RAT", "id": "Q01812-1", "name": "Glutamate receptor ionotropic, kainate 4", "aln": "--------------------------------------MPRVSAPLVLLPAWLLMVACSPH------------SLRIAAILDD-PMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVRFQ--LQRFTTLNLHPSNTDISVAVAGILN-FFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLD-DTRDPTPLLKEIRD-DKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQEN---CDHVPFTG-PALSSALLFDAVYAVVTAVQELNRSQE-IGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFN-----SKGQRSNYALKILQFTRNG---------------FRQIGQWHVAEGLSMDSRLYAS-----NISDSLFNTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSSLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKG--LGMENIGGIFVVLICGLIVAIFMAMLEFLWTLR----HSEAS----------------EVSVCQEMMTELRSIILCQDNIHPRRRR---SGGLPPQPPVLEERRPRGTAT-----LSNGKLCG-AGEPD----------------------QLAQRLAQEAAL--------VARGCTHIRVCPECRRFQGLRARPS----------------PARSEE------------------------SLEWDKTTNSSEPE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMF5-1", "uniprot_id": "GRIK4_MOUSE", "id": "Q8BMF5-1", "name": "Glutamate receptor ionotropic, kainate 4", "aln": "--------------------------------------MPRVSAPLVLLPAWLLMVACSPH------------SLRIAAILDD-PMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVRFQ--LQRFTTLNLHPSNTDISVAVAGILN-FFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLD-DTRDPTPLLKEIRD-DKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQEN---CDHVPFTG-PALSSALLFDAVYAVVTAVQELNRSQE-IGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFN-----SKGQRSNYALKILQFTRNG---------------FQQIGQWHVAEGLSMDSRLYAS-----NISDSLFNTTLVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKG--LGMENIGGIFVVLICGLIVAIFMAMLEFLWTLR----HSEAS----------------EVSVCQEMVTELRNIILCQDNIHPRRRR---SGGLPPQPPVLEERRPRGTAT-----LSNGKLCG-AGEPD----------------------QLAQRLAQEAAL--------VARGCTHIRVCPECRRFQGLRARPS----------------PARSEE------------------------SLEWDKTTNSSEPE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16099-1", "uniprot_id": "GRIK4_HUMAN", "id": "Q16099-1", "name": "Glutamate receptor ionotropic, kainate 4", "aln": "--------------------------------------MPRVSAPLVLLPAWLVMVACSPH------------SLRIAAILDD-PMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQ--FQRFTTLNLHPSNTDISVAVAGILN-FFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLD-DTRDPTPLLKEIRD-DKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQEN---CDHVPFTG-PALSSALLFDAVYAVVTAVQELNRSQE-IGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFN-----SKGQRSNYALKILQFTRNG---------------FRQIGQWHVAEGLSMDSHLYAS-----NISDTLFNTTLVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSN--YAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKG--LGMENIGGIFVVLICGLIVAIFMAMLEFLWTLR----HSEAT----------------EVSVCQEMVTELRSIILCQDSIHPRRRR---AAVPPPRPPIPEERRPRGTAT-----LSNGKLCG-AGEPD----------------------QLAQRLAQEAAL--------VARGCTHIRVCPECRRFQGLRARPS----------------PARSEE------------------------SLEWEKTTNSSEPE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P799-1", "uniprot_id": "A0A8M9P799_DANRE", "id": "A0A8M9P799-1", "name": "Glutamate receptor", "aln": "--------------------------------------MLAAWAPLLFLAMWVRNATSGPL------------SFRIAAILDD-PMECSRGERLAITLAKDSINRSSNRSTTGKLEVDIFELLRDSEYETGETMCQIMSKGVVAVLGPSASPASNSIISNICGEKEVPYVKVAPEDILKVQ--FPRFTTLDLRPTNTDISMAVAGLLT-FFNSSTSCLICAQADCLLNLEVLLRQFLISKETLSVRMLD-DSQDPTPLLKEIRD-DKTATIIVDANATMSHVILERASELGMLSVYYTYILTSLEFSLLRLDDLADQRVNIVGFSVFNRTHPFFQDFVLSLNRSWQEN---CDHAPFAG-TPLSSALLFDAVHTVVAAVQELNRSQN-VGATQLSCKSSKIWEHGTSLMNYLRMVELEGLTGHIEFN-----SKGQRSNYALRIMQNSRDG---------------LRQIGQWHSEQGLSMERKLPSL-----NVTDTLFNTTLTITTILENPYVMLRANHQELEGNDRYEGFCVDMLKELADILKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAEREKVIDFSKPFMTLGISIMYRVHIGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYNPHPCLKGRCSLLINQYSLGNSFWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTMHGGSTMTFFQNSRYQTYQRMWNFMYSKQPSVFVKSTEEGIARVLNSN--YAYLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPLGSVYRDEFDLAILRLQEENRLEILKRKWWDGGKCPKEEDHRAKG--LGMENIGGIFVVLVCGLLVAIFMAVLEFVWMLR----HTPGT----------------ELSVCEEMLRELQGIVLCQDSLQLRRRRG--ASVLRPQPLPLDERRARAAAAS----LSNGKLCTGTGLSE----------------------PLSHRLAQEAAL--------VARGCSHIRICPECRRFQGIRVRPSGPPGAS----------PSHSEE------------------------SIEWEKGTNNSEHE----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P3L5-1", "uniprot_id": "A0A8M1P3L5_DANRE", "id": "A0A8M1P3L5-1", "name": "Glutamate receptor", "aln": "--------------------------------------MPELPALLLSIYFRFLLVTVVTMPPSSLSQTPVLSSVRMAAILDD-SSVCGRGERLALALARENINSVMENPARARVEVDIFELQKDSQYETTDTMCQILPKGVVSVIGPASSPASGSIVSHICGEKEIPHVKIGPEETPRLP--YLRFASVTLYPSNEDLSLAIGSILR-SFSYPSASLVCAKAECLLRLEELIRRFLISRETLSIRMLD-DNLDPTPLLKEIRD-DKIATIIIDANASISYLILKKASELGMTSAFYKYILTTMDFPLLWLDDIVDEQSNIVGFSMFNTTHPFYLEFIRSLNLSWREG---CDINPYPG-PALSSALLFDAVHVVVSAVQELNRSQE-IGVKPLSCTSPQIWQHGTSLMNYLRMVEYDGLTGRVEFN-----SKGQRTNYTLHILEKHRGG---------------HKEIGIWYSNNTLLMNSTSLDI-----NVSETLANKSLIITTILENPYVMRKINYQEFEGNEQYEGFCVDMLRELSDILKFTYRIKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVHIGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLSARLSPYEWYNPHPCLRERRDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESPDDLADQTNIQYGTIHGGSTMTFFMNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVVNSK--YAFLLESTMNEYHRSLNCNLTQIGGLLDTKGYGIGMPLGSPFRDELSLAVLQLQENNRLEILKRRWWEGGKCPKEEDHRAKG--LGMENIGGIFVVLICGLIIAVFVAVMEFVWSTR----RSAETDEVRPLSCDRQYHSHTTVSVCQEMLTEFRNAVSCKKSSRLRRRRPLSSSLALRHPTRITLGAPRPLRLVREMRLSNGKLYSGTGPLTGGSGPGGGPTDMGPGPQRLLEDPLGANSTPAVALGPPAVTVPLPRGCTHVRICQECRRIQSLRTTSCTRIPPSSAPLPRLAPPPPHSSSNTDSEGGGGLSPCRIGHSPPAKGCSLPPPQSSNNTDLMGEQK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BCZ5-1", "uniprot_id": "A0A8M3BCZ5_DANRE", "id": "A0A8M3BCZ5-1", "name": "Glutamate receptor", "aln": "-----------MKFWLLTSFDSR--------------AMEKRKRLLFFFFYSMAKFYLSEQ-----------QVIRIGGIFETRENEPVSMDELAFKFAVTSINRNRTLMPNTTLTYDIQRVNLFDSFEASRRVCDQLALGVAAVFGPSHS-SSVSAVQSICNALEVPHIQTR-WKHPSVD--NKDNFYINLYPEYTSISRAILDIVI-FYKWKCVTVVYEDSTGLMRMQELIKAPSKNNLKIRIRQLPSGGGDSRPLLKEMKK-EKEFYVIFDCSYQVAAELLKQLMSMGMMTEYYHFFFTTLDLFALDLEPYRYSGVNMTAFRLLNLDDSYVASVIQKWSMERQLAPPKPESGLMSGIMTTAAALMYDAVFMVAVAS---QRATQ-MTVSSLQCHRHKPWRYGPRFMNLFKEAQWDGLTGRIVLNK----TDGLRKEFNLDLISLKEDGTAKRVADGASRPNKLWTKIGVWNSYTGLNLTEIKDNK-----NITDSLANRTLIVTTILENPYVMYKKSDKVLYGNDRFEGYCLDLLKELSNILGFTYEVKLVTDGKYGAQNDKGEWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPS-SEVVENNFTLLNSLWFGVAALMRQGSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNSKDGITRVLTTD--YALLMESTSIEYITQRNCNLTQVGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASA--LGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSH----KNSDIE---------------ECVSFSAVMEDLGISLRCHKALRKRGRHR--GRAGLSGVLCNPKRIPRKETMA-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TB31-1", "uniprot_id": "A0A8N7TB31_DANRE", "id": "A0A8N7TB31-1", "name": "Glutamate receptor", "aln": "MSTSASEWKDMLLGWDLFLYGYRRKTDMDVKCSSRRCALLKRTGVSFILLCLMAEVGLSAQ-----------QVLRIGGIFETLENEPISVEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAAVFGPSHS-SSVSAVQSICNALEVPHIQTR-WKHPSVD--NKDSFYINLYPDYASISRAVLDIVQ-FYKWKAVTVVYEDATGLIRLQELIKAPSRYSIKIKIRQLPTGSKDARPLLKEMKK-GKEFCVIFDCSYQTAADVLKQLLSMGMMTEYYHFFFTTLDLYSLDLEPFRYSGVNMTGFRLLNIDNPQVASVVEKWSMERLQAPPKPETGLQDGMMTTEAALMYDAVYMVAAAS---QRASQ-ITVSSLQCHRHKPWRFGSRFISMFKEAQWNGLTGQIIINK----TDGLRKDFDLDIISLKEDGLEKPLESG--RFNKVWKKIGVWNSNTGLNLTDSNKDKN---TNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFSYEVKLVTDGKYGAQNDKGEWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPD-SDVVENNFTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTTD--YALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASA--LGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSR----KNLDIE---------------EVS--------VGQCEWHNKY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMP4-1", "uniprot_id": "Q9VMP4_DROME", "id": "Q9VMP4-1", "name": "", "aln": "----------------------------------MRLCPVVIYAFIIIIGFLEGIIALGGDDR---------NEITVGAIFYE------NEKEIELSFDQAFREVNNMKFSELRFVTIKRYMPTNDSFLLQQITCELISNGVAAIFGPSSK-AASDIVAQIANATGIPHIEYDLKLEATRQEQLNHQMSINVAPSLSVLSRAYFEIIKSNYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKETDETFHEQRIILDCEPKTLKELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFKAN-------ITSVRLKVVDANPFERKKTR-LTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSPWMLGAFIVNEMKTISEDDVEPHFKTENMKLDEYGQRIHFNLEIYKPTVNEP-----------------MMVWTPDNGIKKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEFDYEFMIVNGNGKYNPETK-QWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQD-PDELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKDFNPSAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGIFEFLWNVQNVAVEER----------------VTPWQAFKAELIFALKFWVRKKPMRISSSSDKSSSRRSSGSRRSSKEKSRSKTVS-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :..*: ..: : : : . : ..: *: :. **.:::**: . :: . : *.. :*:.: : : * :* * :: :. :: . * .:: *:. : :* * * * ** . : :*.... :* .: : : :::* :: : . : . .. . . * . . *::*** .. : : : . * . * *. ::. :: . :.: :. : * * .: * : . . : * : . : . :.* *:**.* : . : : *.:::**:.:*:: :*:::: * *.. :* .. : * *:: :** : *::.*. :*** *..*:**: *** *****:: . *: *:*:: :*:::::* * :: .:.. **:: ** *:*. . : * :.: ** *: *..:*:**. : *:. * : *:** *:*:::*:********** :: : .*.* :** .* :.:*:::.**: ** :*. *:: * * . : :.:.....:*: ** . . ** *:*:* * . **:***:* :. * **:. *:** :* :. :::*:*.*...*. :*.:** . . :. :.... *.: ::**:*:** *:::.:::.: **:: : . :. ", "identical_positions": 158, "similar_positions": 286, "identity": "13.75%" }, { "cls_id": "homologset.agr.FB:FBgn0004622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14600-1", "uniprot_id": "NK1R_RAT", "id": "P14600-1", "name": "Substance-P receptor", "aln": "-------------------------MDNVL-PMDSDLF--------------------------------------PNISTNTSE-----SNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAHKRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPS-----RVVCMIEWPEHPN--RTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSD-RYHEQVSAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDY--EGLEMKSTRYLQT-QSSVYKVSRLETTISTVVGAHEEEPEEGPKATPSSLDLTSN------------------------------GSSRSNSKTMTESSSFYSNMLA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30548-1", "uniprot_id": "NK1R_MOUSE", "id": "P30548-1", "name": "Substance-P receptor", "aln": "-------------------------MDNVL-PVDSDLF--------------------------------------PNTSTNTSE-----SNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAHKRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPS-----RVVCMIEWPEHPN--RTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSD-RYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDY--EGLEMKSTRYLQT-QSSVYKVSRLETTISTVVGAHEDEPEEGPKATPSSLDLTSN------------------------------GSSRSNSKTMTESSSFYSNMLA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25103-1", "uniprot_id": "NK1R_HUMAN", "id": "P25103-1", "name": "Substance-P receptor", "aln": "-------------------------MDNVL-PVDSDLS--------------------------------------PNISTNTSE-----PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPS-----RVVCMIEWPEHPN--KIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSD-RYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDY--EGLEMKSTRYLQT-QGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSN------------------------------CSSRSDSKTMTESFSFSSNVLS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16177-1", "uniprot_id": "NK3R_RAT", "id": "P16177-1", "name": "Neuromedin-K receptor", "aln": "---------------MASVPRGENWTDGTV-EVGTHTGNLSSALGV--------TEWLAL--QAGNFSS---ALGLPATTQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPG-----RTLCYVQWPEGPK--QHFT--YHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCD-KYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSY--DELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRDPSAN------------------------------GCSHRGSKSASTTSSFISSPYTSVDEYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47937-1", "uniprot_id": "NK3R_MOUSE", "id": "P47937-1", "name": "Neuromedin-K receptor", "aln": "---------------MASVPTGENWTDGTA-GVGSHTGNLSAALGI--------TEWLAL--QAGNFSS---ALGLPVTSQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLVNFIYGVHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPG-----RTLCYVQWPEGPK--QHFT--YHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCD-KYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSY--DELELKTTRFHPTRQSSLYTVSRMESVTVLYDPSEGDPAKSSRKKRAVPRDPSAN------------------------------GCSHREFKSASTTSSFISSPYTSVDEYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29371-1", "uniprot_id": "NK3R_HUMAN", "id": "P29371-1", "name": "Neuromedin-K receptor", "aln": "---------------MATLPAAETWIDGGG-GVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPG-----RTLCFVQWPEGPK--QHFT--YHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCD-KYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSY--DELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADTTRSSRKKRATPRDPSFN------------------------------GCSRRNSKSASATSSFISSPYTSVDEYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QPL8-1", "uniprot_id": "F1QPL8_DANRE", "id": "F1QPL8-1", "name": "Substance-K receptor", "aln": "-------------------------MDTTLDPLSSSLLY------------------------------------YDEDGNETS------INLFEQPDWQVALWAIAYTLIVIISFIGNVTVIWIILAHKRMRTVTNYFIVNLAFSDASMATFNTVFNFVYALHNDWYFGLGYCKFQNFFPITAMFSSIYSMAAIAVDRYMAIIHPLKPRLSSTTTKLLIGVIWTVAFSLAFPQCYYASTKFYFP-----RTVCMVEWPDDYG--GKHQLSYQIAVIILIYLLPLLVMLVTYSLVGQRLWGSEIPGEASD-HYQNQMQAKRKVVKMMIVVVTTFAICWLPYHIYFILGSFNRDIYKQHYIQQVYLAIFWLAMSSTMYNPIIYCCLNQRFRSGFRKAFQWCPFVKISEE--DNMELQHMRTFHMRRS-----YRTETTSVVVR-NHANEPED-------------------------------------------------------TTSKLIKA---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16610-1", "uniprot_id": "NK2R_RAT", "id": "P16610-1", "name": "Substance-K receptor", "aln": "-------------------------MGTRAIVSDANIL-------------------------------------SGLESNATG------VTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEG-----ATKCVVAWPNDNG--GKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEE--DRLELTHTPSLSR------RVNRCHTKETLFMTGDMTHSEATNGQVGSPQDGE----------------------------------PAGPICKAQA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30549-1", "uniprot_id": "NK2R_MOUSE", "id": "P30549-1", "name": "Substance-K receptor", "aln": "-------------------------MGAHASVTDTNIL-------------------------------------SGLESNATG------VTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGSTFCYFQNLFPVTAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAVIWLVALALASPQCFYSTITVDQG-----ATKCVVAWPNDNG--GKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWGTPTEE--DRLELTHTPSISR------RVNRCHTKETLFMTGDMTHSEATNGQVGGPQDGE----------------------------------PAGP----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21452-1", "uniprot_id": "NK2R_HUMAN", "id": "P21452-1", "name": "Substance-K receptor", "aln": "-------------------------MGTCDIVTEANIS-------------------------------------SGPESNTTG------ITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQG-----ATKCVVAWPEDSG--GKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKE--DKLELTPTTSLST------RVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGL------------------------------WFGYGLLAPTKTHVEI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30975-1", "uniprot_id": "TLR2_DROME", "id": "P30975-1", "name": "Tachykinin-like peptides receptor 99D", "aln": "MENRSDFEADDYGDISWSNWSNWSTPAGVLFSAMSSVLSASNHTPLPDFGQELALSTSSFNHSQTLSTDLPAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECTP-RQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEPFSRRENLTSRYSCSGSPDHNRIKRNDTQKSILYTCPSSPKSHRISHSGTGRSATLRNSLPAESLSSGGSGGGGHRKRLSYQQEMQQRWSGPNSATAVTNSSSTANTTQLLS---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. * * *: .**: : :* : ** *:**::: .*********::**:::: ::::*. .*: * .. * :* :* : :::.: :: *:::: *:: ***:**: *::**:* . : ** : :: * . * **: *:: : * * :*: : :*: :* ** . .:: : ::.** *::** *******:* :*:: : :**::*** *****.:******** :* *** **: .*: * : . * * .: ", "identical_positions": 95, "similar_positions": 94, "identity": "18.16%" }, { "cls_id": "homologset.agr.FB:FBgn0004623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18851-1", "uniprot_id": "GBB_YEAST", "id": "P18851-1", "name": "Guanine nucleotide-binding protein subunit beta", "aln": "MAAHQMDSITYSNNVTQQYIQPQSLQDISAVEDEIQNKIEAARQESKQLHAQINKAKHKIQDASLFQMANKVTSLTKNKINLKPNIVLKGHNNKISDFRWSRDSKRILSASQDGFMLIWDSASGLKQNAIPLDSQWVLSCAISPSSTLVASAGLNNNCTIYRVS-KENRVAQNVASIFKGHTCYISDIEFTDNAHILTASGDMTCALWDIPKAKRVREYSDHLGDVLALAIPEEPNSENSSNTFASCGSDGYTYIWDSRSPSAVQSFYVNDSDINALRFFKDGMSIVAGSDNGAINMYDLRSDCSIATFSLFRGYEERTPTPTYMAANMEYNTAQSPQTLKSTSSSYLDNQGVVSLDFSASGRLMYSCYTDIGCVVWDVLKGEIVGKLEGHGGRVTGVRSSPDGLAVCTGSWDSTMKIWSPGYQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P29829-1", "uniprot_id": "GBB2_DROME", "id": "P29829-1", "name": "Guanine nucleotide-binding protein subunit beta-2", "aln": "--------------------MPKIDPETQKLYDEINGMIQKFKDDQK-----------SKADCTLADKCGDMGDVPKIRFSSKK--ILKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGNFVACGGMDNQCTVYDVNNRDASGVAKMVKELMGYEGFLSSCRFLDDGHLITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSP------DMKTYITGSVDKTAKLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQYEPPQ-----------------------------------KNTGFTSCALSTSGRYLMCGGIEGNVHSWDTMKQRHTGTLSGHENRITCISLCPNGMCLASTSWDQQVRLWL----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : . : ***:. *: :::.* . *.:* : ...: .:.* ::. * :**** **:...::: **:: ::.* ** ::***: :. * : *** * **:: *:***..:**..*::*:**:* *. :: . ::.. : *: ::*. .* *:.*::*.****. . **: *. :. ::..* **: .*::. . :*: : . * : :** *. . * *: :* *:.:: :. .*:.:.: *:: : .*****:* .** :. : .* *..* :*:*** : . : . **.:* . .*.*.** .*:* : .*:*:.:.: ***. :::* ", "identical_positions": 101, "similar_positions": 151, "identity": "23.82%" }, { "cls_id": "homologset.agr.FB:FBgn0004635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAW6-1", "uniprot_id": "D4AAW6_RAT", "id": "D4AAW6-1", "name": "Rhomboid-related protein 3", "aln": "-------------------------MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAP---------EDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLEARTRVALFLYNGVLLDQFVLQVTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSM-------------------------------------------------EFGRAVWLRFHP-SAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNIFAYTLLDLKLPPPP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58873-1", "uniprot_id": "RHBL3_MOUSE", "id": "P58873-1", "name": "Rhomboid-related protein 3", "aln": "-------------------------MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAP---------EDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLE----VALFLYNGVLLDQFVLQVTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSM-------------------------------------------------EFGRAVWLRFHP-SAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNIFAYTLLDLKLPPAP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58872-1", "uniprot_id": "RHBL3_HUMAN", "id": "P58872-1", "name": "Rhomboid-related protein 3", "aln": "-------------------------MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAP---------EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLE----VAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSM-------------------------------------------------EFGRAVWLRFHP-SAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75783-1", "uniprot_id": "RHBL1_HUMAN", "id": "O75783-1", "name": "Rhomboid-related protein 1", "aln": "MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQ----IIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSS-------------------------------------------------EVGRAVWLRFSP-PLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC82-1", "uniprot_id": "RHBL1_MOUSE", "id": "Q8VC82-1", "name": "Rhomboid-related protein 1", "aln": "-----------------------------------MDRSSLLQLIQE------------------------------QQLDPENTGFIGADTFAGLVHSHELPLDPTKLDMLVALAQSNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLSVYKRFVRYVAYEILPCEVDRRWYFYRHRTCPPPVFMASVTLAQ----IIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSS-------------------------------------------------EVGRAVWLRFSP-PLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGADIPPPP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88779-1", "uniprot_id": "RHBL1_RAT", "id": "O88779-1", "name": "Rhomboid-related protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSS-------------------------------------------------EVGRAVWLRFSP-PLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFL-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YY16-1", "uniprot_id": "A0A8M6YY16_DANRE", "id": "A0A8M6YY16-1", "name": "Rhomboid-related protein 1", "aln": "-----------------------------------MDRSSLFQLIQE-------------------------------QLDPEQTGFITVENFTSLAEHHELQLDPSKLEMLLALVQSNEHGHVCYQELIELLNSKRSSSFRRAIANGRRTLQREILLDETGLGVYKRFVRYVAYEILPCETDRRWYFHQNRLCPPPVFMAVITIVQ----IMVFMCYGVMLNKWVLQTYQPDFMKSPLVYHPGHRAQIWRFFSYMFMHVGLEQLGFNALLQLMIGVPLEMVHGILRISLLYMAGVIAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMKCPYKLLRMILALVCMSS-------------------------------------------------EVGRAVWLRFSP-PLPSSGPQPSFMAHLSGAVVGISMGLLILRSYEESLHKQCSWWVLIFSFVTFLLFAIFWNIFAYELLGVQIPPPP-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20350-1", "uniprot_id": "RHOM_DROME", "id": "P20350-1", "name": "Protein rhomboid", "aln": "-------------------------------------MENLTQNVNET------------------------------KVDLGQE----KEKEASQEEEHATAAKETIIDIPAACSSSSNSS--SYDTDCSTASSTCCTRQGEHIYMQREAIPATPLPESEDIGLLKYVHR----------------------QHWPWFILVISIIE----IAIFAYDRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHLANITLNYAHMKS--ASTQLGSVVIFVSC-------------------------------------------------DLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNLINTVTAQLMEEQGEVITQHLLHDLGVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LN46-1", "uniprot_id": "A0ABK0LN46_RAT", "id": "A0ABK0LN46-1", "name": "Rhomboid-related protein 2", "aln": "-----------------------------------------------------------------------------------------------MAAAHEMEMESVNLNMEREGKEELEEEKMRGDGEGKDFPRGR---------KVHRIVSKWMLPEPVRRTYLERAN----------------------CLPPPLFIVLISLAE----LAVFIYYAVWKPQKQWITLDTGILESPLTYRPEKREEAWRFISYMLVHAGVQHIVGNLFMQLVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPALGIVRLLVIILIALVGSNELMEGELQDQQPAGQQSKARPGQREQNPAHCGDPRLHWASSLLVASDMGFALYRRFFV---PANGSPVSFAAHIAGGFAGMSVGYTVFSCFDKTLLKDPRFWISIAAYVACLLFAVFFNIFLSPAN---------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.. :: * :**..*:***::* *:.::*:***.**** *: * :**.******* ..:: *: :*: * :: :: :.* *:: :: . . *: **: * .*:::* :: : . .: :*: : : ", "identical_positions": 41, "similar_positions": 56, "identity": "8.12%" }, { "cls_id": "homologset.agr.FB:FBgn0004636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JI6-1", "uniprot_id": "RAP1B_MOUSE", "id": "Q99JI6-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGK-ARKKSSCQLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61224-1", "uniprot_id": "RAP1B_HUMAN", "id": "P61224-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGK-ARKKSSCQLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NIZ1-1", "uniprot_id": "RP1BL_HUMAN", "id": "A6NIZ1-1", "name": "Ras-related protein Rap-1b-like protein", "aln": "MREYKLVVLGSRGVGKSALTVQFVQGIFVEKYDPTIEDSYREQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGK-ARKKSSCQLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62636-1", "uniprot_id": "RAP1B_RAT", "id": "Q62636-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGK-ARKKSSCQLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6TEN1-1", "uniprot_id": "RAP1B_DANRE", "id": "Q6TEN1-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNSCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------TGK-PRKKSTCQLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62835-1", "uniprot_id": "RAP1A_MOUSE", "id": "P62835-1", "name": "Ras-related protein Rap-1A", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------EKK-KPKKKSCLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62834-1", "uniprot_id": "RAP1A_HUMAN", "id": "P62834-1", "name": "Ras-related protein Rap-1A", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------EKK-KPKKKSCLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62836-1", "uniprot_id": "RAP1A_RAT", "id": "P62836-1", "name": "Ras-related protein Rap-1A", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------EKK-KPKKKSCLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7FBI4-1", "uniprot_id": "E7FBI4_DANRE", "id": "E7FBI4-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------EKKKAKKKSNCVLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08645-1", "uniprot_id": "RAP1_DROME", "id": "P08645-1", "name": "Ras-related protein Rap1", "aln": "MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFN-CAFMETSAKAKVNVNDIFYDLVRQINK-------------------------------------------------------------KSPE--------------------------KKQKKPKKSLCVLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13856-1", "uniprot_id": "RSR1_YEAST", "id": "P13856-1", "name": "Ras-related protein RSR1", "aln": "MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRLPSSAKQDTKQSNNKQSSKGLYNKSSQGQAKVKQSTPVNEKHKPSHAVPKSGSSNRTGISATSQQKKKKKNASTCTIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**:****: *****.******* ::::.**********: :*:* : ******** ******:**:*.* ** ****:* :.::::* :****:**:**:: ***:*:***.** :***:. * * ::: :: .* *:** : ** ::* ****** : .:* : : . * :*", "identical_positions": 96, "similar_positions": 51, "identity": "35.29%" }, { "cls_id": "homologset.agr.FB:FBgn0004638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62993-1", "uniprot_id": "GRB2_HUMAN", "id": "P62993-1", "name": "Growth factor receptor-bound protein 2", "aln": "MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ--QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62994-1", "uniprot_id": "GRB2_RAT", "id": "P62994-1", "name": "Growth factor receptor-bound protein 2", "aln": "MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ--QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60631-1", "uniprot_id": "GRB2_MOUSE", "id": "Q60631-1", "name": "Growth factor receptor-bound protein 2", "aln": "MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQMPQ--QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08012-1", "uniprot_id": "GRAP_DROME", "id": "Q08012-1", "name": "Growth factor receptor-bound protein 2", "aln": "MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSN-KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLR--DMIP---EEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVTPYHS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q13588-1", "uniprot_id": "GRAP_HUMAN", "id": "Q13588-1", "name": "GRB2-related adapter protein", "aln": "MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::* :.*.** .***:*.: : **:** * *.***:*** * :*:**.***.:* * *: *:*.* **::* : .* ****** ***:**:**:**: : ********:. .*:*** *********:::*::::::.::: ** : : .** :** .*: .:*.*****.* * :..* :**.* .: *:** .** * : ", "identical_positions": 101, "similar_positions": 67, "identity": "46.12%" }, { "cls_id": "homologset.agr.FB:FBgn0004643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8C2-1", "uniprot_id": "ZW10_RAT", "id": "Q4V8C2-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--SLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQRLERDSVVLNLLKQLQE-FSSAIEEYNSALAEKKYIPAAR-LLEEAQECLKLLKSKKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPSKDTSSLESCLQTELHLCTEQPEKE-MTPLPSISSVLLAFSILGELPTKLKS---FGQMLLKYILKPLVTCP--SLHAVIERQPNSVSICFQSLATDSEHPPPPEAFAKIQLVLEVLQKQLLDLPLDADLEIGKVPEIVLAEMLGEVIWEDLSDCLIRNCLVYSIPTNSSKLQQYEEIIQSTEEFEKSLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARHLMTSEIHNTVKIGPDCEETLPDLPSPDADHRLQVQ-VCKVQFTDAGNLEPETSLDPRSFSLPTCRISEAVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRSRLTPI--LCDGTTTFVDLVPGFRRLGTECFLAQMRTQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTVIAEMIGRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54692-1", "uniprot_id": "ZW10_MOUSE", "id": "O54692-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--SLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQQLERDSVVLTLLKQLQE-FSSAIEEYNSALAEKKYIPAAR-HLEEAQECLKLLKSRKCFDLKMLKSLSMELTVQKQNILYHLGEDWQKLVVWKFPPAKDTSSLESCLQTELHLCTEQPEKEDMTPLPSISSVLLAFSILGELPTKLKS---FGQMLLKYILKPLVTCP--SLHAVIERQPSSVSICFESLTTDLEHPSPPEAFAKIRLVLEVLQKQLLDLPLDADLEIGKVPGIVLAEMLGEGIWEDLSECLIRNCLVYSIPTNSSKLQEYEEIIQSTEEFEKFLKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIGPDCKEALPDLPSPDADHKLQVQTVCKAQFTDAGNLEPETSLDPQSFSLPTCRISEAVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLRKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI--LCDGTTTFVDLVPGFRRLGTECFLAQMQAQKGELLERLSSARSFANMDDEENYSAASKAVRQVLHQLRRLGIVWQDVLPVNIYCKAMGTLLNTAIAEMMSRITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43264-1", "uniprot_id": "ZW10_HUMAN", "id": "O43264-1", "name": "Centromere/kinetochore protein zw10 homolog", "aln": "------MASFVTEVLAHSG--RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQE-FSTAIEEYNCALTEKKYVTGAQ-RLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKS---FGQMLLKYILRPLASCP--SLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI--LCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4X9-1", "uniprot_id": "ZW10_DROME", "id": "Q9W4X9-1", "name": "Centromere/kinetochore protein zw10", "aln": "MEEEAPRFNVLEEAFNGNGNGCANVEATQSAILKVLTRVNRFQMRVRKHIEDNYTEFLPNNTSPDIFLEESGSLNREIHDMLENLGSEGLDALDEANVKMAGNGRQLREILLGLGVSEHVLR-IDELFQCVEEAKATKDYLVLLD-LVGRLRAFIYGDDS--------VDGDAQVATPEVRRIFKALECYETIKVKYHVQAYMLQQSLQERFDRLVQLQCKSFPTSRCVTLQVSRDQTQLQDIVQALFQEPYNPARLCEFLLDNCIEPVIMRP--VMADYSEEADGGTYVRLS-LSYATKEPSSAHVRPNYKQVLENLRLLLHTL---AGINCSVSRDQHVFGIIGDHVKDKMLKLLVDECLIPAVPESTEEYQTSTLCEDVAQLEQLLVDSFIINPEQDRALGQFVEKYETYYRNRMYRRVLETAREIIQRDLQDMVLVAPN-------------------------------NHSAEVANDP--FLFPRCMISKSAQDFVKLMDRILRQPTDKLGDQEADPIAGVISIMLHTYINEVPKVHRKLLESIPQQAVLFHNNCMFFTHWVAQHAN-------------KGIESLAALAKTLQATGQQHFRVQVDYQSSILMG---IMQEFEFESTHTLGSGPLKLVRQCLRQLELLKNVWANVLPETVYNATFCELINTFVAELIRRVFTLRDISAQMACELSDLIDVVLQRAPTLFREPNE-----------VVQVLSWLKLQQLKAMLNASLMEITELWGDGVGPLTASYKSDEIKHLIRALFQDTDWRAKAITQIV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53847-1", "uniprot_id": "DSL1_YEAST", "id": "P53847-1", "name": "Protein transport protein DSL1", "aln": "----------MESLFPNKG------EIIRELLKDPLILKNDSKRSNGSELELDSSDLLQREAILANELNILDNLKTFLNLIKEVKTNLNILELENCYYSLQSLRKKMRNNAAYLKQSFNFQQSISTYVDTLHLELVSTLYKILTNGFWKITENSIQFTPTVEWGKDKVHIEYDTFMDFVAQQYFPKGSLDNQAWFILDMTSADSQEQVRAKLNTIMKEYMNLSRIVSMIKNSIFISGKEISYENEKNILVFSKSSSHGQHCVSTVLTSFEAVCDFMLDGLAFRDRKTLSYELGPLFNTEFTKFVKNNASIILESLDSPLKNLVSVINNKLTRLVAKSEVTNWTHSGKEIQDLLMNKQLYYNLLLDKVLES-HISEIRSIFEDPKKSWQNLEVVELTTSNTNTMSEKIGKNDSDVQNEKELHNAVSKDDDWNWEVEDDDADAWGDEIDVN---------------IDDEEEKTNQEKEKEPEEEENAWDEAWAIDENIDDASLENGKEHLKAHDVGSLDKDHIEVTQLPKLFLAISQNFKSSFADSHVDEQYFAYKYNLLQTSYMAMCTANFSHNWCQLYVDMRYLIERDEKLYRIKELTRNLLETKLNMKYRIVCQLIRHQLTEFRENE--RNPSWDATIEKLLPYILKEIVRPLQKIRGEEGSRYLLSFLNFLYNDCVTKEILKWQIISEVNSENLGELVSLLVNNTDIQLLAKE---------------PSYKKMREKFATMGKFLPLHLKEIMEMFYNG---DFYLFATDELIQWIELLFADTPLRRNAIDDIYEIRGTALDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .* * : : : . :. . :::* : ..*. :. : . . *. . .: . :::.. * :. . :. .: . . . * . : : :. : . .. . ..:. :: :: : . . : :. : .. : : : . . *: * : . *. : : : . : *: .: . . : .: :. . : : : : : :: *. : . ::.: . : . * : : . . .: . :: . * *: : :: : .. . : . : ::: .: . .: : : : : : :. : * : *::: . : * * ::: : : : ::.:: .* .* : : : :* * ** : : :* : :.*: *. ** :* * *: .* ", "identical_positions": 34, "similar_positions": 183, "identity": "4.22%" }, { "cls_id": "homologset.agr.FB:FBgn0004644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63673-1", "uniprot_id": "SHH_RAT", "id": "Q63673-1", "name": "Sonic hedgehog protein", "aln": "------------------------------------------------------------MLLLLARCFLVALASSLLVCPGLACGPGRGFG-KRQHPKK-LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKARIHCSVKAENSVAAKSDGCFPGSATVHLEQGGTKLVKDLSPGDRVLA---ADDQGRLLYSDFLTFLDRDEGAKKVFYVIETREPRERLLLTAAHLLFVAP-HND-----------SGPTPG----PSPLFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEAAGAYAPLTADGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTD----------GGGGGSIPAPQS-VAEARGAGPPAGIHWYSQLLYHIGTWLLDSETLHPLGMAVKSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62226-1", "uniprot_id": "SHH_MOUSE", "id": "Q62226-1", "name": "Sonic hedgehog protein", "aln": "------------------------------------------------------------MLLLLARCFLVILASSLLVCPGLACGPGRGFG-KRRHPKK-LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLA---ADDQGRLLYSDFLTFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAP-HND-----------SGPTPG----PSALFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTD----------GGGGGSIPAAQS-ATEARGAEPTAGIHWYSQLLYHIGTWLLDSETMHPLGMAVKSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15465-1", "uniprot_id": "SHH_HUMAN", "id": "Q15465-1", "name": "Sonic hedgehog protein", "aln": "-------------------------------------------------------------MLLLARCLLLVLVSSLLVCSGLACGPGRGFG-KRRHPKK-LTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLA---ADDQGRLLYSDFLTFLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAP-HNDSATGEPEASSGSGPPSGGALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92008-1", "uniprot_id": "SHH_DANRE", "id": "Q92008-1", "name": "Sonic hedgehog protein", "aln": "------------------------------------------------------------MRL-LTRVLLVSLLTLSLVVSGLACGPGRGYG-RRRHPKK-LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNSLAISVMNHWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDKSKYGTLSRLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSALVSLQDGGQKAVKDLNPGDKVLA---ADSAGNLVFSDFIMFTDRDSTTRRVFYVIETQEPVEKITLTAAHLLFVL---DN-----------STEDLH---TMTAAYASSVRAGQKVMVVDDSGQ----LKSVIVQRIYTEEQRGSFAPVTAHGTIVVDRILASCYAVIEDQGLAHLAFAPARLYYYVSSFLFPQ------------------------NSSSRSNATLQQEGVHWYSRLLYQMGTWLLDSNMLHPLGMSVNSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90419-1", "uniprot_id": "TWHH_DANRE", "id": "Q90419-1", "name": "Tiggy-winkle hedgehog protein", "aln": "----------------------------------------------------------MDVRLHLKQFALLCFISLLLTPCGLACGPGRGYG-KRRHPKK-LTPLAYKQFIPNVAEKTLGASGKYEGKITRNSERFKELIPNYNPDIIFKDEENTNADRLMTKRCKDKLNSLAISVMNHWPGVKLRVTEGWDEDGHHLEESLHYEGRAVDITTSDRDKSKYGMLSRLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSGTVTLGDGTRKPIKDLKVGDRVLA---ADEKGNVLISDFIMFIDHDPTTRRQFIVIETSEPFTKLTLTAAHLVFVG---NS-----------SAASG-----ITATFASNVKPGDTVLVWEDTCES---LKSVTVKRIYTEEHEGSFAPVTAHGTIIVDQVLASCYAVIENHKWAHWAFAPVRLCHKLMTWLFP---------------------------ARESNVNFQEDGIHWYSNMLFHIGSWLLDRDSFHPLGILHLS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LP42-1", "uniprot_id": "F1LP42_RAT", "id": "F1LP42-1", "name": "Hedgehog protein", "aln": "--------------------------------------------------------MSPAWLRPRLRFCLLL-LLLLLVPAARGCGPGRVVGSRRRPPRK-LVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVHLETGERVALSAVKPGDRVLA-MGEDGN--PTFSDVLIFLDREPNRLRAFQVIETQDPPRRLALTPAHLLFI----------------ADNHTEP-AARFRATFASHVQPGQYVLVA-----GVPGLQPARVAAISTHVALGSYAPLTRHGTLVVEDVVASCFAAVSDHHLAQLAFWPLRLFPSLPW-----------------------------------GSWTPSEGVHWYPQLLYRLGRLLLEESTFHPLGMSGAGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97812-1", "uniprot_id": "IHH_MOUSE", "id": "P97812-1", "name": "Indian hedgehog protein", "aln": "--------------------------------------------------------MSPAWLRPRLRFCLFL-LLLLLVPAARGCGPGRVVGSRRRPPRK-LVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLENGERVALSAVKPGDRVLA-MGEDGT--PTFSDVLIFLDREPNRLRAFQVIETQDPPRRLALTPAHLLFI----------------ADNHTEP-AAHFRATFASHVQPGQYVLVS-----GVPGLQPARVAAVSTHVALGSYAPLTRHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFPSLAW-----------------------------------GSWTPSEGVHWYPQMLYRLGRLLLEESTFHPLGMSGAGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14623-1", "uniprot_id": "IHH_HUMAN", "id": "Q14623-1", "name": "Indian hedgehog protein", "aln": "--------------------------------------------------------MSPARLRPRLHFCLVL-LLLLVVPAAWGCGPGRVVGSRRRPPRK-LVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLA-MGEDGS--PTFSDVLIFLDREPHRLRAFQVIETQDPPRRLALTPAHLLFT----------------ADNHTEP-AARFRATFASHVQPGQYVLVA-----GVPGLQPARVAAVSTHVALGAYAPLTKHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFHSLAW-----------------------------------GSWTPGEGVHWYPQLLYRLGRLLLEEGSFHPLGMSGAGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98862-1", "uniprot_id": "IHH_DANRE", "id": "Q98862-1", "name": "Indian hedgehog B protein", "aln": "-------------------------------------------------------------MRLSTAAALLTGFILAFSPAYDGCGPGRGYG-KRRTPRK-LTPLAYKQFSPNVAEKTLGASGRYEGKVTPSSERFKELTPNYNPDIIFKDEENTGADRMMTQRCKDKLNSLAISVMNLWPGVRLRVTEGWDEDGLHSEESLHYEGRAVDITTSDRDRNKYRMLARLAVEAGFDWVYYESKGHVHCSVKSEHSVAAKTGGCFPGRALVTMKDGSHRQIRDLQAGDLVLASEGSDGTGDLIYSEVLTFLDRRPITQKHFYVIRTEDG-ASVSLTAAHLLFMRVGN------------CSNRGEPKPGAVRTIFASDAQVGQCLLLG-----KLR-KRFSQITHVGVREDQGLYPPLTAHGTVVVNDVLTSCYAAVNRQRLAHWAFAPLRLLYSWTG-----------------------------------PDQVLKNGLHWYSQVLIGLGKLLLDSELFHPLALEATER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V7Y0-1", "uniprot_id": "G3V7Y0_RAT", "id": "G3V7Y0-1", "name": "Hedgehog protein", "aln": "--------------------------------------------------------------MALPASLLPLCCLALLALSVQSCGPGRGPVGRRRYVRKQLVPLLYKQFVPSMPERTLGASGPAEGRVTRGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHIHVSVKADNSLAVRAGGCFPGNATVRLRSGERKGLRELHRGDWVLA---ADAAGRVVPTPVLLFLDRDLQRRASFVAVETERPPRKLLLTPWHLVFAAR--------------GPAPAPG---DFAPVFARRLRAGDSVLAP-----GGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLP--------------------------------GGAVQPTGMHWYSRLLYRLAEELMG--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61488-1", "uniprot_id": "DHH_MOUSE", "id": "Q61488-1", "name": "Desert hedgehog protein", "aln": "--------------------------------------------------------------MALPASLLPLCCLALLALSAQSCGPGRGPVGRRRYVRKQLVPLLYKQFVPSMPERTLGASGPAEGRVTRGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHIHVSVKADNSLAVRAGGCFPGNATVRLRSGERKGLRELHRGDWVLA---ADAAGRVVPTPVLLFLDRDLQRRASFVAVETERPPRKLLLTPWHLVFAAR--------------GPAPAPG---DFAPVFARRLRAGDSVLAP-----GGDALQPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLP--------------------------------GGAVQPTGMHWYSRLLYRLAEELMG--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43323-1", "uniprot_id": "DHH_HUMAN", "id": "O43323-1", "name": "Desert hedgehog protein", "aln": "--------------------------------------------------------------MALLTNLLPLCCLALLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLA---ADASGRVVPTPVLLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAAR--------------GPAPAPG---DFAPVFARRLRAGDSVLAP-----GGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLP--------------------------------GGAVQPTGMHWYSRLLYRLAEELLG--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02936-1", "uniprot_id": "HH_DROME", "id": "Q02936-1", "name": "Protein hedgehog", "aln": "MDNHSSVPWASAASVTCLSLDAKCHSSSSSSSSKSAASSISAIPQEETQTMRHIAHTQRCLSRLTSLVALLLIVLPMVFSPAHSCGPGRGLG--RHRARN-LYPLVLKQTIPNLSEYTNSASGPLEGVIRRDSPKFKDLVPNYNRDILFRDEEGTGADRLMSKRCKEKLNVLAYSVMNEWPGIRLLVTESWDEDYHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSISSHVHGCFTPESTALLESGVRKPLGELSIGDRVLS---MTANGQAVYSEVILFMDRNLEQMQNFVQLHTDGG-AVLTVTPAHLVSVWQ---------------PESQK-----LTFVFADRIEEKNQVLVR---DVETGELRPQRVVKVGSVRSKGVVAPLTREGTIVVNSVAASCYAVINSQSLAHWGLAPMRLLSTLEAWLPAKEQLHS--------------------SPKVVSSAQQQNGIHWYANALYKVKDYVLPQSWRHD--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .***** *: :: * ** ** *.:.* * .*** ** : .* :*::* **** **:*:***.:.***:*::***:::* ** :*** ***::* ***.**** * ::********: *:*****:.** *:*********** * *: ::: ***:: * : : ***. . . : * : : ** **: : .: * *: * :.* : :*. **: :* . : : * .*:* .**:::: : :**:*.: : *: .: * ** *:***.. * : :: ", "identical_positions": 125, "similar_positions": 87, "identity": "23.63%" }, { "cls_id": "homologset.agr.FB:FBgn0004647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R172-1", "uniprot_id": "NOTC3_RAT", "id": "Q9R172-1", "name": "Neurogenic locus notch homolog protein 3", "aln": "MGPGARGRRRRRRL----------MALPPPPPPMRALPLLLLLLAGLG--------AAAPPCLDGSPCANGGRCTHQQPSREAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGVARFSCRCLR-----------------------------------------GFRGPDCSLPDPCFSSPCAHGAPCSVGS-DGRYACACPPGYQGRNCRSDIDECRAG-ASCRHGGTCINTPGSFHCLCPLGYTGLLCENPIVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-ACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCS-HGVCHDAPGGFQCVCDPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFHCTCAPGFQGHQCEV---------------------------------------LSPCTPSLCEHGGHCESDPDQLTV-CSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGSFRCICHGGYTGPFCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCLSGFAGPRCARDVDECLSSPCGPG-TCTDHVASFTCTCPPGYGGFHCETDLLDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGTHCQYKVDPCFSRPCLHGGICNPTHSGFECTCREGFTGNQCQNPVDWCSQAPCQNGGRCVQTG--AYCICPPEWSGPLCDIPSLPCTEAAAHMGVRLEQLCQAGGQCIDKDHSHYCVCPEGRMGSHCEQEVDPCTAQPCQHGGTCRGYMGGYVCECPTGYSGDSCEDDVDECASQPCQNGGSCIDLVAHYLCSCPPGTLGVLCEINEDDCGPGPS-LDSGLRCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGTCHAAHTRDCLQDPGGHFRCICLPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVG-IPCQQTARGPRCACPPGLSGPS---CRVSRASPSGATNTSCAATPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSA----------------APEVPEE-PRCPRAACQAKRGDQNCDRECNSPGCGWDGGDCSLNVDDPWRQC-EALQCWRLFNNSRCDPACSSPACLYDNFDCYSGGRDRTCNPVYKKYCADHFADGRCDQGCNTEECGWDGLDCASEVP-ALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDARGQAMVFPYH---------------------------------RPSPGSESRVRRELG-PEVIGSVVMLEIDNRLCLKSAENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEPPE---QSVPLLPLLVAGAVFLLVIFVLG--VMVARRKREHSTLWFPEGFALHKDIAAGHKGRREPVGQDALGMKNMTK-GES-LMGEVATDWND--SECPEAKRLK---VEEPGMGAE-------------EPVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALEPMPAEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ--------------------PSGPRSP---------------------------------------------------------------------------------------SGPHGLGPLLCPPGAFLPGLKAVQSGTKK-------SRRPPGKTGLG------------------------------------------------------------------------------PQGTRGRGKK----------------------------------LTLACPGPLADSSVTLSPVDSLDSPRPFGGPPASP------------------GGFPLEGPYAT-TATTVSLAQ----LGASRAGPLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGSQLLNPATPVSPHERPPPYLAAPG---------------------------------HGEEYPAAGTHS-------------------------------SPTKARFLRVPSEH---PYLTPSPESPEHWASPSPPSLSDWSDSTPSPATAT--SATAAGALP-AQPHPISVP-SLPQSQTQLGPQPEVTPKRQVMA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61982-1", "uniprot_id": "NOTC3_MOUSE", "id": "Q61982-1", "name": "Neurogenic locus notch homolog protein 3", "aln": "MGLGARGRRRRRRL----------MALPPPPPPMRALP-LLLLLAGLG--------AAAPPCLDGSPCANGGRCTHQQPSLEAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLR-----------------------------------------GFQGPDCSQPDPCVSRPCVHGAPCSVGP-DGRFACACPPGYQGQSCQSDIDECRSG-TTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-ACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCS-HGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEV---------------------------------------LSPCTPSLCEHGGHCESDPDRLTV-CSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPG-TCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRCVQTG--AYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGPS-LDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVG-IPCQQTARGPRCACPPGLSGPS---CRVSRASPSGATNASCASAPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSA----------------APEVPEE-PRCPRAACQAKRGDQNCDRECNTPGCGWDGGDCSLNVDDPWRQC-EALQCWRLFNNSRCDPACSSPACLYDNFDCYSGGRDRTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVP-ALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDARGQAMVFPYH---------------------------------RPSPGSESRVRRELG-PEVIGSVVMLEIDNRLCLQSAENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEAPE---QSVPLLPLLVAGAVFLLIIFILG--VMVARRKREHSTLWFPEGFALHKDIAAGHKGRREPVGQDALGMKNMAK-GES-LMGEVVTDLND--SECPEAKRLK---VEEPGMGAE-------------EPEDCRQWTQHHLVAADIRVAPATALTPPQGDADADGVDVNVRGPDGFTPLMLASFCGGALEPMPAEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHLANREITDHLDRLPRDVAQERLHQDIVRLLDQ--------------------PSGPRSP---------------------------------------------------------------------------------------SGPHGLGPLLCPPGAFLPGLKAVQSGTKK-------SRRPPGKTGLG------------------------------------------------------------------------------PQGTRGRGKK----------------------------------LTLACPGPLADSSVTLSPVDSLDSPRPFSGPPASP------------------GGFPLEGPYAT-TATAVSLAQ----LGASRAGPLGRQPPGGCVLSFGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGAPVSPQERPPPYLAAPG---------------------------------HGEEYPAAGTRS-------------------------------SPTKARFLRVPSEH---PYLTPSPESPEHWASPSPPSLSDWSDSTPSPATAT--NATASGALP-AQPHPISVP-SLPQSQTQLGPQPEVTPKRQVMA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UM47-1", "uniprot_id": "NOTC3_HUMAN", "id": "Q9UM47-1", "name": "Neurogenic locus notch homolog protein 3", "aln": "MGPGARGRRRRRRP----------MSPPPPPPPVRALP-LLLLLAGPG--------AAAPPCLDGSPCANGGRCT-QLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPR-----------------------------------------GFRGPDCSLPDPCLSSPCAHGARCSVGP-DGRFLCSCPPGYQGRSCRSDVDECRVG-EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-ACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECS-IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL---------------------------------------LSPCTPNPCEHGGRCESAPGQLPV-CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTG--AYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPP-LDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVG-VPCQQTPRGPRCACPPGLSGPS---CRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA----------------APEVSEE-PRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC-EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVP-ALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYH---------------------------------RPSPGSEPRARRELA-PEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEPPE---PSVPLLPLLVAGAVLLLVILVLG--VMVARRKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDALGMKNMAK-GES-LMGEVATDWMD--TECPEAKRLK---VEEPGMGAE-------------EAVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ--------------------PSGPRSP---------------------------------------------------------------------------------------PGPHGLGPLLCPPGAFLPGLKAAQSGSKK-------SRRPPGKAGLG------------------------------------------------------------------------------PQGPRGRGKK----------------------------------LTLACPGPLADSSVTLSPVDSLDSPRPFGGPPASP------------------GGFPLEGPYAAATATAVSLAQ----LGGPGRAGLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVPG---------------------------------HGEEYPAAGAHS-------------------------------SPPKARFLRVPSEH---PYLTPSPESPEHWASPSPPSLSDWSESTPSPATATGAMATTTGALP-AQPLPLSVPSSLAQAQTQLGPQPEVTPKRQVLA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07207-1", "uniprot_id": "NOTCH_DROME", "id": "P07207-1", "name": "Neurogenic locus Notch protein", "aln": "-MQSQRSRRRSRAPNTWICFWINKMHAVASLPASLPLLLLTLAFANLPNTVRGTDTALVAASCTSVGCQNGGTCVTQLNG-KTYCACDSHYVGDYCEHRNPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHV-TCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQS--NPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGICR-SNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCATGYKGVDCSEDIDECD-QGS-PCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNSFKCLCDPGYTGYICQKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCPPGYTGKRC--ELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCN-NGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPG--------ACHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVN-NYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCN--IRQSG---HHCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEH---CEID-------TLDECSPNPCAQGAACEDLLGD--YECLCPSKWKGKRCDIYDANYPGWNGGSGSGNDRYAADLEQQRAMCDKRGCTEKQGNGICDSDCNTYACNFDGNDCSLGIN-PWANC-TANECWNKFKNGKCNEECNNAACHYDGHDCER--KLKSCDSLFDAYCQKHYGDGFCDYGCNNAECSWDGLDCENKTQSPVLAEGAMSVVMLMNVEAFREIQAQFLRNMSHMLRTTVRLKKDALGHDIIINWKDN------------------------------VRVPEIEDTDFARKNK-ILYTQQVHQTGIQIYLEIDNRKCTECFTHAVEAAEFLAATAAKHQLRNDFQIHSVRGIKNPGDEDNGEPPANVKYVITGIILVIIALAFFGMVLSTQRKRAHGVTWFPEGFRAPAAVMS--RRRRDPHGQEMRNLNKQVA-MQSQGVGQPGAHWSDDESDMPLPKRQRSDPVSGVGLGNNGGYASDHTMVSEYEEADQRVWSQAHLDVVDVR-----AIMTPPAHQDGGKHDVDARGPCGLTPLMIAAVRGGGLDTGEDIEN-NEDSTAQVISDLLAQGAELNATMDKTGETSLHLAARFARADAAKRLLDAGADANCQDNTGRTPLHAAVAADAMGVFQILLRNRATNLNARMHDGTTPLILAARLAIEGMVEDLITADADINAADNSGKTALHWAAAVNNTEAVNILLMHHANRDAQDDKDETPLFLAAREGSYEACKALLDNFANREITDHMDRLPRDVASERLHHDIVRLLDEHVPRSPQMLSMTPQAMIGSPPPGQQQPQLITQPTVISAGNGGNNGNGNASGKQSNQTAKQKAAKKAKLIEGSPDNGLDATGSLRRKASSKKTSAASKKAANLNGLNPGQLTGGVSGVPGVPPTNSAAQAAAAAAAAVAAMSHE-------LEGSPVGVGMGGNLPSPYDTSSMYSNAMAAPLANGNPNTGAKQPPSYEDCIKNAQSMQSLQGNGLDMIKLDNYAYSMGSPFQQELLNGQGLGMNGNGQRNGVGPGVLPGGLCGMGGLSGAGNGNSHEQGLSPPYSNQSPPHSVQSSLALSPHAYLGSPSPAKSRPSLPTSPTHIQAMRHATQQKQFGGSNLNSLLGG--ANGGGVVG----GGGGGGGGVG-QGPQNSPVSLGIISPTGSDMGIMLAPPQSSKNSAIMQTISPQQQQQQQQQQQQQHQQQQQQQQQQQQ--------------------------QQQQQLGGLEFGSAGLDLNGFCGSPDSFHSGQMNPPS-----IQSSMSGSSPSTNMLSPSSQHNQQAFYQYLTPSSQHSGGHTPQHLVQTLDSYPTPSPESPGHWSSSSPRS-NSDWSEGVQSPAANNLYISGGHQANKGSEAIYI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07008-1", "uniprot_id": "NOTC1_RAT", "id": "Q07008-1", "name": "Neurogenic locus notch homolog protein 1", "aln": "--------------------------MPRLLAPLLCLTLLP-ALAARG----------LRCSQPSGTCLNGGRCE-VAN-GTEACVCSGAFVGQRCQDPSPCLSTPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLANACLAN-PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFE--SSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN-ACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECA-LGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFLCQCPKGFSGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGLCKDGVATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCEINLDDCASNPCDSG-TCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCI-HGACRDGLNGYKCDCAPGWSGTNC--DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKS-PCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPTGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVN-DFHCECRAGHTGRRCESVINGCRGKPCRNGGVCAVASNTARG--FICRCPAGFEGATCENDARTCGSLRCLNG-GTCISGPRSPTCLCLGSFTGPE---CQFP------ASSPCVGSNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFTG-------GAGRDIPPP-QIEEACELPECQEDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQL--TEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVP-ERLAAGTLVLVVLLPPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYYGREEELRKHPIKRSAVGWAT----------TSLLPG-TNGGRQRRELDPMDIHGSIVYLEIDNRQCVQ--SSSQCFQSATDVAAFLGALASLGSLNIPYKIEAVKSETVEPPL----PSQLHLMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKV---SEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQNEWGDEDLET-KKFRFE-EPVVLPDLDDQ---------------TDHRQWTQQHLDAADLRVS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEE--EDAPA-VISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILLRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGTALGGTPTLSPTLCSP------------------NGYLGNLKSA-----TQGKKAR---KPSTKGLACSSKEAKDLKARRKKSQDGKGCLLDS----------SSMLSPVDSLESPHGYLSDVASPPLLPSP-------FQQSP-SMPLS-----------------------------------------------------------------------------HLPGMPDTHLG-------------------------------ISHLNVAAKPEMAALAGGSRLAFEPPPPRLSHLPVASSASTVLSTNGTGAMNFTVGAPASLNGQCEWLPRLQNGMVP-SQYNPLRPGVTPGTLSTQAAGLQHGMMGPIHSSLSTNTLSPII-YQGLPNTRLATQPHLVQTQQVQPQNLQIQPQNLQ--------------PPSQPHLSVSSAANGHLGRSFLSGEPSQADVQPLGPSSLPVHTILPQESQ--ALPTSLPSSMVPPMTTTQFLTPPSQH--------SYSSSPVDNTPSHQLQVPE-HPFLTPSPESPDQWSSSSPHSNISDWSEGISSPPTSMPSQITHIPEAFK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01705-1", "uniprot_id": "NOTC1_MOUSE", "id": "Q01705-1", "name": "Neurogenic locus notch homolog protein 1", "aln": "--------------------------MPRLLTPLLCLTLLP-ALAARG----------LRCSQPSGTCLNGGRCE-VAN-GTEACVCSGAFVGQRCQDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLAN-PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFE--SSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN-ACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECA-LGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMDKINEFQCQCPKGFNGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSG-TCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCI-HGACRDGLNGYKCDCAPGWSGTNC--DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKS-PCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPVGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVN-DFHCECRAGHTGRRCESVINGCRGKPCKNGGVCAVASNTARG--FICRCPAGFEGATCENDARTCGSLRCLNG-GTCISGPRSPTCLCLGSFTGPE---CQFP------ASSPCVGSNPCYNQGTCEPTSENPFYRCLCPAKFNGLLCHILDYSFTG-------GAGRDIPPP-QIEEACELPECQVDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQL--TEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVP-ERLAAGTLVLVVLLPPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYYGHEEELRKHPIKRSTVGWAT----------SSLLPG-TSGGRQRRELDPMDIRGSIVYLEIDNRQCVQ--SSSQCFQSATDVAAFLGALASLGSLNIPYKIEAVKSEPVEPPL----PSQLHLMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKV---SEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQNEWGDEDLET-KKFRFE-EPVVLPDLSDQ---------------TDHRQWTQQHLDAADLRMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEE--EDAPA-VISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILLRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGTALGGTPTLSPTLCSP------------------NGYLGNLKSA-----TQGKKAR---KPSTKGLACGSKEAKDLKARRKKSQDGKGCLLDS----------SSMLSPVDSLESPHGYLSDVASPPLLPSP-------FQQSP-SMPLS-----------------------------------------------------------------------------HLPGMPDTHLG-------------------------------ISHLNVAAKPEMAALAGGSRLAFEPPPPRLSHLPVASSASTVLSTNGTGAMNFTVGAPASLNGQCEWLPRLQNGMVP-SQYNPLRPGVTPGTLSTQAAGLQHSMMGPLHSSLSTNTLSPII-YQGLPNTRLATQPHLVQTQQVQPQNLQLQPQNLQ--------------PPSQPHLSVSSAANGHLGRSFLSGEPSQADVQPLGPSSLPVHTILPQESQ--ALPTSLPSSMVPPMTTTQFLTPPSQH--------SYSSSPVDNTPSHQLQVPE-HPFLTPSPESPDQWSSSSPHSNISDWSEGISSPPTTMPSQITHIPEAFK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46531-1", "uniprot_id": "NOTC1_HUMAN", "id": "P46531-1", "name": "Neurogenic locus notch homolog protein 1", "aln": "--------------------------MPPLLAPLLCLALLP-ALAARG----------PRCSQPGETCLNGGKCE-AAN-GTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTN-PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFE--ASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN-ACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS-LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPGWSGTNC--DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLS-PCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARG--FICKCPAGFEGATCENDARTCGSLRCLNG-GTCISGPRSPTCLCLGPFTGPE---CQFP------ASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGG-------GAGRDIPPP-LIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQR--AEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVP-ERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYYGREEELRKHPIKRAAEGWAAPD-ALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEIDNRQCVQ--ASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPP----PAQLHFMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKV---SEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQNEWGDEDLET-KKFRFE-EPVVLPDLDDQ---------------TDHRQWTQQHLDAADLRMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEE--EDAPA-VISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSP------------------NGYLGSLKPG-----VQGKKVR---KPSSKGLACGSKEAKDLKARRKKSQDGKGCLLDS----------SGMLSPVDSLESPHGYLSDVASPPLLPSP-------FQQSP-SVPLN-----------------------------------------------------------------------------HLPGMPDTHLG-------------------------------IGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVP-NQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESP--ALPTSLPSSLVPPVTAAQFLTPPSQH--------SYSS-PVDNTPSHQLQVPE-HPFLTPSPESPDQWSSSSPHSNVSDWSEGVSSPPTSMQSQIARIPEAFK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46530-1", "uniprot_id": "NOTC1_DANRE", "id": "P46530-1", "name": "Neurogenic locus notch homolog protein 1", "aln": "--------------------------MNRFLVKLTLLTAASLATVAQG----------QRCS---EYCQNGGICE-YKPSGEASCRCPADFVGAQCQFPNPCNPSPCRNGGVCRPQMQGNEVGVKCDCVLGFSDRLCLTPVNHACMNS-PCRNGGTCSLLTLDTFTCRCQPGWSGKTCQLADPCASNPCANGGQCSAFE--SHYICTCPPNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPHCQRLYQPCLPSPCRSGGTCVQTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGPCIDGINTYNCHCDKHWTGQYCTEDVDECELSPN-ACQNGGTCHNTIGGFHCVCVNGWTGDDCSENIDDCASAACSHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTCPPGYTGSACNQDIDECS-LGANPCEHGGRCLNTKGSFQCKCLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCASQPCLN-GKCIDKINSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECTPGFSGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYG-KCIDKINGYECVCEPGYSGSMCNINIDDCALNPCHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSSNPCI-HGSCLDQINSYRCVCEAGWMGRNC--DININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRN-PCTNGGVCENLRGGFQCRCNPGFTGALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCECVPGYHGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRCFNGGRCVDRVGGYGCVCPAGFVGERCEGDVNECLSDPCDPSGSYNCVQLIN-DFRCECRTGYTGKRCETVFNGCKDTPCKNGGTCAVASNTKHG--YICKCQPGYSGSSCEYDSQSCGSLRCRNG-ATCVSGHLSPRCLCAPGFSGHE---CQTR------MDSPCL-VNPCYNGGTCQPISDAPFYRCSCPANFNGLLCHILDYSFSG-------GQGRDIAPPVEVEIRCEIAQCEGRGGNAICDTQCNNHACGWDGGDCSLNFDDPWQNCSAALQCWRYFNDGKCDEQCATAGCLYDGFDCQR--LEGQCNPLYDQYCRDHYADGHCDQGCNNAECEWDGLDCADDVP-QKLAVGSLVLVVHIPPDELRNRSSSFLRELSSLLHTNVVFRRDANGEALIFPYYGSEHELSKHKRS----DWTDPG-QLMQRARRSLTSFLKP--RTRRELDHMEVKGSIVYLEIDNRQCFQ--QSDECFQSATDVAAFLGALASSGNLNVPYIIEAVTSE-GGPPK----TGEMYPMFLVLLALAVLALAAVGVVVSRKRKREHGQLWFPEGFKV---NEP-KKKRREPVGEDSVGLKPLKN-SDSSLMDEQLSEWAEDDTN--KRFRFE-GQSIL-EMSGQ---------------LDHRQWTQQHLDAADLRLN-SMAPTPPQGQIENDCMDVNVRGPDGFTPLMIASCSGGGLENENGEAE--EDPSADVITDFIYHGANLHNQTDRTGETALHLAARYARSDAAKRLLESCADANVQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMHDGTTPLILATRLAVEGMVEELINCHADPNAVDDSGKSALHWAAAVNNVDAAVVLLKNGANKDLQNNKEETPLFLAAREGSYETAKVLLDHLANRDIADHLDQLPRDIAHERMHHDIVRLLEEYNLVRSPPLP---------LSPPLCCP------------------NTYLG-IKPSPGNNNNTAKKTR---KPGGKGVGGKDS-GKDIRTKKKKSGDGKNGGIME----------VGVLSPVDSLESPHGYLSDVSSPPMMTSP-------FQQSP-PISLN-----------------------------------------------------------------------------QLQGLADSHMG-------------------------------GALQGLGKPFDS--------------APRLSHLPVAN-----------------NVGG-AQAGACDWLQRVQ-------QQQQQQ------QQQQQAGMLMPTMLSATN-------MPQVMGYPTMQSSHLG----APSHMIAHQNMAPMQHQNIS--------------------------------HHFLG-DLSGLDLQSSSG-HAPIQTILPQDSQ--RM---APP-----ISSTQFLTPPSQH--------SYSNPMDN-TPNHQ-QVPD-HPFLTPSAGSPDQWSSSSPHSNLSDWSEGISSPPTSMQ--MNHIPEAFK------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BFY6-1", "uniprot_id": "A0A8M2BFY6_DANRE", "id": "A0A8M2BFY6-1", "name": "Neurogenic locus notch homolog protein 1", "aln": "--------------------------MHLFFVKL--IVVISLNTLTQG----------LECS---EKCQNGGTCE-PTADGRGECKCLDLYAGPACQFRNPCFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGA-PCRNGGTCELTSIHNYRCKCPPGWSGKTCQQADPCASNPCANGGQCSPFD--SDFLCHCTPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGTYHCNCPAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPN-SCQNGGTCLNTQGGYNCVCVNGWTGDDCSENIDDCADAACHTGATCHDRVASFLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPLGYVGPACDQDVDECS-LGANPCEHAGKCINTKGSFQCKCLQGYVGARCELDINECLSTPCQNDATCLDQIGGFHCICMPGYEGVFCQINTDECASMPCLNNGKCIDKINNYQCECPTGFSGSQCQFDIDECASTPCKNGAKCMDGPNMYTCQCTEGYTGQHCETDVDECLSNPCHYGTCKDGLASFTCVCRAGFMGRLCEININECLSQPCQNGGTCQDRENAYLCVCPKGTAGANCEINLDDCQSNPCDFG-RCIDKINGYECACEPGYTGKMCNVNIDECAINPCHNGGTCVDGVNGFTCLCREGYHDTTCQSQLNECLSNPCI-HGHCEDKVNGYNCICDSGWSGVNC--DINNNECESNPCMNGGTCKDMTSGYVCTCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLAPCGSKPCKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVKN-PCRNDAICQNSIGSYKCSCKAGYTGRNCETDIDDCKPNPCSNGGFCKDAVNAFTCTCLPGFRGGRCEEDINECESNPCKNGANCTDCVNSYTCTCPPGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPKGFTGNYCQHDINECDSRPCMNGGTCQDSYGTYKCTCPQGYHGLNCQELVNWCKPSPCKNGGICRQSGTRYSCQCQTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCECVPGYHGVNCSDEINECLSQPCQNGGTCIDLINTYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGGYHCICPPGYVGERCEGDVNECLSNPC---GTHSCIQLKN-NYRCECRTGYTGQHCDKVFDGCKGKPCRNGGTCAVASNTPHG--FICKCPPGFTGSTCEYDAHACGSLQCKNG-GTCVSGHKSPKCLCTPAFTGPE---CQDP------SGGHCT-TNPCYNGGTCEYITEEPYYHCICPTNFNGLFCHILDWSFPG-------GTGQDITPAPKVSVSCEIEQCKVKKGNKICDSACNNYACDWDGGDCSLNFNDPWKNCSAALQCWRYFNNGKCDEQCHNTGCLYDGFDCQR--VEAQCNPLYDQYCKDHFADGYCDQGCNNAECEWDGLDCANDTP-EKLAAGLLVVVVHIHPDQLRNNSFGFLRELSRVLHTNVVFRRDSKGQEMIYPYYGNEQELKKHNIKRSLDGWNDASSDVLSSMKNSIYNIVVEGGRKRRELEKIQVKGSVVYLEIDNRQCYQ--QTSECFQSANDAAAFLGALASSGSLKMPYVIEAVTSE-IDGPS----PVELYPVYVVLAGLALLAFVAIGMVASRKRRREHGQLWFPEGFKT---SEPSKKKRREPVGEDSVGLRPLKNCSDISLMDDNQNEWGEEEQSDSKRFRSE-EQAML-DLDDQ---------------PDHRQWTQQHLDAADLRIP-SIAPTPPQGEIENDCMDVNARGPDGFTPLMIASCSGGGLETGNSEEE--EDASANVINDFIYQGANLHNQTDRTGETALHLAARYARSDAAKRLLEASADANIQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMVEELINCHADVNAIDDFGKSALHWAAAVNNVDAAMVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMDRLPRDIAQDRMHHDIVRLIDEYNLVRSPPMHSAPL--CTTLSPPLCSP------------------NGFMGNMKPS-----VQSKKPR---KPSTKGIGCKD--GKDMKVKKKKAQDGKGNLLDS----------SAVLSPVDSLESPHGYISDIASPPQMTSP-------FQQSP-SMSLN-----------------------------------------------------------------------------QLQGMSDNHMG-------------------------------VSHLGIGNNQDLSHI------QFDPLPPRLTHLPVAG-----------------SNGSNVMNGQCEWLERMHGSMAPQNQFTAMR------NASGQANLHQSGLMTSHHNGRPA-TLSQMMNYQSMQNTHLMQQ--MQQSMQPRPQQTGVQLQSQS--------------------------------QNFIGGDLGGPELQQSAGNSMSIHTIIPQETQ--LL---NPSSLGSSMAGTQFLTPPSQH--------SYTPALDANTPNHQLQVPDHHPFLTPSPGSPDQWSSSSPNSNMSDWSEGISSPPTSMQSQIGHMPEQFK------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0DPK3-1", "uniprot_id": "NT2NB_HUMAN", "id": "P0DPK3-1", "name": "Notch homolog 2 N-terminal-like protein B", "aln": "--------------------------MPALRPALLWALLALWLCCATP-------AHALQCRDGYEPCVNEGMCVTYHN-GTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLG--KATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVA--NQFSCKCLTGFTGQKCETDVNECDIP-GHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP--ETVR--RGTELWE-------------------RDREVWNGKEHDEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A096LNW5-1", "uniprot_id": "NT2NR_HUMAN", "id": "A0A096LNW5-1", "name": "Notch homolog 2 N-terminal-like protein R", "aln": "--------------------------MPALRPALLWALLALWLCWAAP-------AHALQCRDGYEPCVNKGMCVTYHS-GTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLG--KATCRCASGFTGEDCQYSTPHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHLCANGSTCTTVA--NQFSCKCLTGFTGQKCETDVNECDIP-GHCQHGGTCLNLPGSYQCQCLQGFTGQYCDRLYVPCAHSPCVNGGTCRQTGDFTFECNCLP--ETVRNKRNRALGK-------------------RQASLEWKRTR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04721-1", "uniprot_id": "NOTC2_HUMAN", "id": "Q04721-1", "name": "Neurogenic locus notch homolog protein 2", "aln": "--------------------------MPALRPALLWALLALWLCCAAP-------AHALQCRDGYEPCVNEGMCVTYHN-GTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLG--KATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVA--NQFSCKCLTGFTGQKCETDVNECDIP-GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN-ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYKCLCDAGWVGINC--EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK-PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPH-------CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN-DYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG--FICRCPPGFSGARCQS---SCGQVKCRKG-EQCVHTASGPRCFCPSPRDCESGCAS-----------------SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPST------------------PPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINN-QCDELCNTVECLFDNFECQG----NSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQP-ENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMK-------------------------KQRMTRRSLPGEQEQEV--AGSKVFLEIDNRQCVQ--DSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQ---------LLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLR--RDASNHKRREPVGQDAVGLKNLSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDD--------------PIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDED-AEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLS------------------------LKHTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSES----------SVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLA----------------------------------------------------------------------------------TAAPPAPVHAQH---------------------------------ALSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVL-----APAEGTHP-GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMAR--------------------------------LPSVAFPTAMMPQQDGQVAQTILPAYHPFP---------------ASVGKYPTPPSQHS-------YASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHS-ASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQVYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QW30-1", "uniprot_id": "NOTC2_RAT", "id": "Q9QW30-1", "name": "Neurogenic locus notch homolog protein 2", "aln": "--------------------------MPALRPAALRALLWLWLCGAGP-------AHALQCRGGQEPCVNEGTCVTYHN-GTGYCRCPEGFLGEYCQHRDPCEKNRCQNGGTCVTQAMLG--KATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSWDTYECTCQVGFTGKQCQWTDVCLSHPCENGSTCSSVA--NQFSCRCPAGITGQKCDADINECDIP-GRCQHGGTCLNLPGSYRCQCPQRFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFTSECHCLPGFEGSNCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN-ACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCLCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQAYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGTLCDENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCLHG-ACVDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKDATCINDVNGFRCMCPEGPHHPSCYSQVNECLSSPCI-HGNCTGGLSGYKCLCDAGWVGINC--EVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCLDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFTCLCAPGWQGQRCTVDVDECVSK-PCMNNGICHNTQGSYMCECPPGFSGMDCEEDINDCLANPCQNGGSCVDKVNTFSCLCLPGFVGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINECSSNPCLNSGTCVDGLGTYRCTCPLGYTGKNCQTLVNLCSPSPCKNKGTCAQEKARPRCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAGAPH-------CLNGGQCVDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLKN-NYQCVCRSAFTGRHCETFLDVCPQKPCLNGGTCAVASNVPDG--FICRCPPGFSGARCQS---SCGQVKCRRG-EQCVHTASGPHCFCPNHKDCESGCAS-----------------NPCQHGGTCYPQRQPPYYSCRCSPPFWGSHCESYTAPTST------------------PPATCLSQYCADKARDGICDEACNSHACQWDGGDCSLTMEDPWANCTSSLRCWEYINN-QCDELCNTAECLFDNFECQR----NSKTCKYDKYCADHFKDNHCDKGCNNEECGWDGLDCAADQP-ENLAEGILVIVVLLPPEQLLQDSRSFLRALGTLLHTNLRIKQDSQGALMVYPYYGEKSAAMK-------------------------KQKVARRSLPDEQEQE--IIGSKVFLEIDNRQCVQ--DSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESEDPRNTP---------LLYLLAVAVVIILFLILLGVIMAKRKRKHGFLWLPEGFTLR--RDSSNHKRREPVGQDAVGLKNLSVQVSEANLIGSTTSEHWGDDEGPQPKKAKAEDDEALLSEDD--------------PVDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDED-AEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVLCGPNRSFLS------------------------LKHTPMGKKARRPNTKSTMPTSLPNLAKEAKDVKGSRRKKCLNEKVQLSES----------SVTLSPVDSLESPHTYVSDATSSPMITSPGILQASPTPLLA----------------------------------------------------------------------------------AAP-AAPVHAQH---------------------------------ALSFSNLHEMQPLRPGASTVLPSVSQLLSHHHIVPPGSGSAGSLGRLHSVPVPSDWMNRVEMSETQYSEMFGMVL-----APAEGTHPGMAAPQSRAPEGKPIPTQREPLPPIVTFQLIPKGSLAQAAGAPQTQSGCPPAVAGPLPSMYQIPEMAR--------------------------------LPSVAFPPTMMPQQEGQVAQTIVPTYHPFP---------------ASVGKYPTPPSQHS-------YASSNAAERTPNHGGHLQGEHPYLTPSPESPDQWSSSSPHS-ASDWSDVTTSPTPGGGGGGQRGPGTHMSEPPHSNMQVYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35516-1", "uniprot_id": "NOTC2_MOUSE", "id": "O35516-1", "name": "Neurogenic locus notch homolog protein 2", "aln": "--------------------------MPALRPAALRALLWLWLCGAGP-------AHALQCRGGQEPCVNEGTCVTYHN-GTGFCRCPEGFLGEYCQHRDPCEKNRCQNGGTCVPQGMLG--KATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDTYECTCQVGFTGKQCQWTDACLSHPCENGSTCTSVA--SQFSCKCPAGLTGQKCEADINECDIP-GRCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN-ACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTCIDRVASFSCLCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGILCDENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCMHG-VCVDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYKCLCDAGWVGVNC--EVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISK-PCMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINECSSNPCLNAGTCVDGLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCVQEKARPHCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCPLGYTGSYCEEQLDECASNPCQHGATCNDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDECAGGPH-------CLNGGQCVDRIGGYTCRCLPGFAGERCEGDINECLSNPCSSEGSLDCVQLKN-NYNCICRSAFTGRHCETFLDVCPQKPCLNGGTCAVASNMPDG--FICRCPPGFSGARCQS---SCGQVKCRRG-EQCIHTDSGPRCFCLNPKDCESGCAS-----------------NPCQHGGTCYPQRQPPHYSCRCPPSFGGSHCELYTAPTST------------------PPATCQSQYCADKARDGICDEACNSHACQWDGGDCSLTMEDPWANCTSTLRCWEYINN-QCDEQCNTAECLFDNFECQR----NSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCASDQP-ENLAEGTLIIVVLLPPEQLLQDSRSFLRALGTLLHTNLRIKQDSQGALMVYPYFGEKSAAMK-------------------------KQKMTRRSLPEEQEQEQEVIGSKIFLEIDNRQCVQ--DSDQCFKNTDAAAALLASHAIQGTLSYPLVSVFSELESPRNAQ---------LLYLLAVAVVIILFFILLGVIMAKRKRKHGFLWLPEGFTLR--RDSSNHKRREPVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDEGPQPKKAKAED-EALLSEDD--------------PIDRRPWTQQHLEAADIRHTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDED-AEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVLCGPNRSFLS------------------------LKHTPMGKKARRPNTKSTMPTSLPNLAKEAKDAKGSRRKKCLNEKVQLSES----------SVTLSPVDSLESPHTYVSDATSSPMITSPGILQASPTPLLA----------------------------------------------------------------------------------AAAPAAPVHTQH---------------------------------ALSFSNLHDMQPLAPGASTVLPSVSQLLSHHHIAPPGSSSAGSLGRLHPVPVPADWMNRVEMNETQYSEMFGMVL-----APAEGAHPGIAAPQSRPPEGKHMSTQREPLPPIVTFQLIPKGSIAQAAGAPQTQSSCPPAVAGPLPSMYQIPEMPR--------------------------------LPSVAFPPTMMPQQEGQVAQTIVPTYHPFP---------------ASVGKYPTPPSQHS-------YASSNAAERTPSHGGHLQGEHPYLTPSPESPDQWSSSSPHS-ASDWSDVTTSPTPGGGGGGQRGPGTHMSEPPHSNMQVYA", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * * * * : * *: .** * . *.* . * * *: * *. : * * * :*. * : * * . * .* *::** *: ** * * *:: * * .** *: ** *** ** * .. : * * . : : ", "identical_positions": 51, "similar_positions": 27, "identity": "1.8%" }, { "cls_id": "homologset.agr.FB:FBgn0004648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHW1-1", "uniprot_id": "CBPD_RAT", "id": "Q9JHW1-1", "name": "Carboxypeptidase D", "aln": "MASGWDERPPWRLESLRLLPPPPLLLLLLLLRSSAQAAHIKKAEATTTTVG-GSEAAEGQFDHYYHEAALGEALEAAAAAGPPGLARLFSIGNSVEGRPLWVLRLTAGLG-----PPPTPAAVGLDAAGPLLPGRPQVKLVGNMHGDETVSRQVLVYLARELASGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGLGDSGPPGTSGRDNSRGRDLNRSFPDQFSTG---EPPSLDEVPEVRALIDWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKTTGIYSKTSDDEVFRYLAKAYASNHPIMRTGEPHCPGDEEETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGIKGFVKDSVTGSGLENATISVAGINHN-ITTGRFGDFHRLLIPGSYNLTAVSPGYMPLTINNIVVKEGPATEIDFSLQ----------PTVMSVVPDSTEAVTTPGTVAVPNIPPGTPSSHQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVRSTRIHLMPSMNPDGYEKSQEGDSISVVGRNNSNNFDLNRNFPDQF--VPITDPTQPETIAVMSWVKAYPFVLSANLHGGSLVVNYPYDDNEQGVAT--------------YSKSPDDAVFQQIALSYSKENSQMFQGRPCKDMYLN-EYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPFEKELPKYWEQNRRSLIQFMKQVHQGVKGFVLDATDGRGILNATLSVAEINHPVTTYKAGDYWRLLVPGTYKITASARGYNPVTKNVTVRSEGAIQVNFTLVRSSTD----ANNESKKGKGHSTSTDDTSDPTSKEFEALIKHLSAENGLEGFMLSSSS--DLALYRYHSYKDLSEFLRGLVMNYPHITNLTTLGQSVEYRHIWSLEISNKPNIS-------------EPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLN----YKKNPVVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKTGHTNARGRDLDTDFTS-NASQ------PETKAIIENLIQKQDFSLSIALDGGSVLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSCPN----------NSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAAQLPALWAENKK----SLLSMLVEVHKGVHGLVKDKTGKPISKAVIVLNEGIRVHTKE---GGYFHVLLAPGVHNINAIADGYQQQHSQVFV-HHDAASS-VVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIWCICSIKSNRHKDGFH-------------RLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89001-1", "uniprot_id": "CBPD_MOUSE", "id": "O89001-1", "name": "Carboxypeptidase D", "aln": "MASGRDERPPWRLGRLRLLPPPPLLLLLLLLRSSAQAAHIKKAEATTTTVG-GSEAAEGQFDHYYHEAALGEALEAAAAAGPPGLARLFSIGSSVEGRPLWVLRLTAGLG-----PPPT-AAAGLDAAGPLLPGRPQVKLVGNMHGDETVSRQVLVYLARELASGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGLGDSGPPGTSGRDNSRGRDLNRSFPDQFSTG---EPPSLDEVPEVRALIDWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKTTGLYSKTSDDEVFRYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGIKGFVKDSVTGSGLENATISVAGINHN-ITTGRFGDFHRLLVPGTYNLTALSTGYMPLTINNIMVKEGPATEMDFSLR----------PTVMSVMPGSTEAVTTPGTVAVPNIPPGTPSSHQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVRSTRIHLMPSMNPDGYEKSQEGDSISVVGRNNSNNFDLNRNFPDQF--VPITEPTQPETIAVMSWVKAYPFVLSANLHGGSLVVNYPYDDNEQGVAT--------------YSKSPDDAVFQQIALSYSKENSQMFQGRPCKDMYLN-EYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPFENELPKYWEQNRRSLIQFMKQVHQGVKGFVLDATDGRGILNATLSVAEINHPVTTYKAGDYWRLLVPGTYKITASARGYNPVTKNVTVRSEGAVQVNFTLVRSSAD----ANNESKKGRGHSTSTDDTSDPTSKEFEALIKHLSAENGLEGFMLSSSS--DLALYRYHSYKDLSEFLRGLVMNYPHITNLTTLGQSVEYRHIWSLEISNKPNIS-------------EPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLN----YKRNPVVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKTGHTNAHGKDLDTDFTS-NASQ------PETKAIIENLIQKQDFSLSIALDGGSVLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSCPN----------NSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAAQLPALWAENKK----SLLSMLVEVHKGVHGLVKDKAGKPISKAVIVLNEGIKVYTKE---GGYFHVLLAPGVHNINAIADGYQQQHTQVFV-HHDAASS-VVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIWCICSIKSNRHKDGFH-------------RLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75976-1", "uniprot_id": "CBPD_HUMAN", "id": "O75976-1", "name": "Carboxypeptidase D", "aln": "MASGRDERPPWRLG--RLL----LLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTG---EPPALDEVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHN-ITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLR----------PTVTSVIPDTTEAVSTASTVAIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISVIGRNNSNNFDLNRNFPDQF--VQITDPTQPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLAT--------------YSKSPDDAVFQQIALSYSKENSQMFQGRPCKNMYPN-EYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRSSTD----SNNESKKGKGASSSTNDASDPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVS-------------EPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLN----YKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKIGQTNARGKDLDTDFTN-NASQ------PETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMHMGQPSCPN----------KSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKR----SLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKE---GGYFHVLLAPGVHNIIAIADGYQQQHSQVFV-HHDAASS-VVIVFDTDNRIFGLPRELVVTVSGATMSALILTACIIWCICSIKSNRHKDGFH-------------RLRQHHDEYEDEIRMMSTGSKKSLLSHEFQDETDTEEETLYSSKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5H7-1", "uniprot_id": "A0ACD6B5H7_DANRE", "id": "A0ACD6B5H7-1", "name": "Carboxypeptidase D", "aln": "-MSGQRARDLCSAN------KCPLLLLSLLVVYISPINSVSAGELKTETYN-----------KYYNYDELTELLKSLAVK-HPSIANLTSIGRSVEGRELWVMRVTKDIS-------------AADGAG-----KPKFKYVGNMHGDETVSRQVLVYLLEDLLEKYGE-DQRVTELVNTTDIYILPSMNPDGFERSVEGDCVGKD------EGRHNAKNIDLNRSFPDQFEEI---HLN-AEDIPEVTAVIKWILENKFVLSGNLHGGTVVASYPYDDSAGHSTDGTYSRSPDDALFRHLALVYAENNPVMKTGQPKCEDNVNESFPDGITNGAKWYDVPGGMQDFNYLKGNCLEITMELSCCKYPPSSQLKTEWENNRDALLAYMEQIHIGVRGFVRAAKNEAPIADAVIMVADIKHN-VSTSRFGDYYRLLLPGTYSITAVAPGYIPMTVAGVEVKEGKATVLNITLLSENDERSTATPNPESSTDTSASSSNSGSTDNNSNSGASDKAADLTIQPQEFRHHRYIDMELFMKKFSSEYSSITRLYSIGKSVQKRLLWVMEISNNPGVHELGEPEFKYIGNMHGNEVVGRELLLNLIEYLCRNYGTDPEVTQLVDTTRIHIMPSMNPDGYEVSQKGDVEGIKGRNNSKNYDLNRNFPDRF--KLITDPIQPETLAVMNWSKNYSFVLSANLHGGSLVVNYPFDDNLEDVIG--------------YSKSPDDAVFRMVALAYSQENSEMREGHPCKEMSSYPEYFQDGITNGAAWYNVHGGMQDWNYMNTNCFEVTIELGCHKYPPVADLQKYWEQNRKSLLQFIHQVHRGVKGMVIDSKDGSGIPNATITVETIHHQVTSSSLGDYWRLLVPGKYKLTASAQGYTSDSSSVTVPKDGLEIVNFTLTRIPTH----ANGQ------ETENTTPVLDPSVREFQALIKQLSTQSGLDKLIQDTPT---ESSFRYQQYGEVSEFLRGLTLNFPEITSLRSLGQSVEIRNIWALEISNNPKVQ-------------EPSKPKIRFVAGIHGNAPVGTELLLQFAESLCVN----YGKNAAINRLINETRIVILPSINPDGRELAKERDCTSTVGMTNVHGKDLDTDFIVGNASQRVSEPQPETRAVMN-LIQERGFTLSVALDGGSLLVTYPYDKPVQTVENDDTLRYLATVYADHHPTMHLGNTGCPN----------SVQSNIPGGVLRAAVWHSHMGSMKDFSVDFGHCPEITVYTSCCLFPSAEMLPSLWAENRK----SLLSMLVEVHKGVRGIVKDKNGKPIVGAAIVLNGGVRVYTSE---GGYFHALLAPGLHSIEAVADGYQQQSQKVSVSQFEAASS-IIIEFDMENDIFGLPRELVVASAAAAMTALVLTACIIWCVCSAKSNRHKDGFH-------------RLRQHRDDYDDEVRLMSMGSKKSLLSHEFQDESESDEDTLYTNKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42787-1", "uniprot_id": "CBPD_DROME", "id": "P42787-1", "name": "Carboxypeptidase D", "aln": "--------------------MPTLGLLFASIGIAVLAMGVPHCRGYTIKED-----ESFLQQPHYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTR-------------------SRNLLTPPVKYIANMHGDETVGRQLLVYMAQYLLGNHER-ISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPN----YVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKG-----NNCNDSFSGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDAS-GFPIADANVYVAGLEEKPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQEALRLDFK------------LAPVETNFDGNFRKVKVERSEPPQKLKKQFNGFLTPTKYEHHNFTAMESYLRAISSSYPSLTRLYSIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERYGNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTGGVGRANAHGIDLNRNFPDQYGTDRFNKVTEPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQPC-ELFQN-EFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHS-TIGTPIAGAVVRLDGANHSTYSQVFGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRMDITLMPDDPQHWASANDFRIIENVVNTRYHTNPQVRARLAELENQNGQIASFGYADSEFGTIFNYLKMTSDIGEPEEHKYKLLVVSSLYDTTAPLGREILLNLIRHLVEGFKLQDTSVVELLKRSVIYFLPQTSKFQNVFDMYNSNTSICDPVLGDELAERILGPETDQAKDVFLQFLRSERFDLMLTFGAGNSDLNYPKGDSVLVKFAHRMQRTEFNYSPLQCPPSATRQLHRETTERLTNMMYRIYNLPVYTLGISCCRMPHQKKIASVWRKNIDKIKNFLALVKTGVSGLVQNDKGQPLREAYVRLLEHDRIINVTKNVARFQLMLPHGLYGLEVTAPNYESQMIKVDVEDGRVTELGIIRMHPFTLIRGVVLELPNNDNRATTSIAGVVLDESNHPVRNAKVSVVGQTQLRNFTGSMGQYRISAVPLGTITLKVEAPRHLEATRQMHLIQGGLATENVVFHLKVNEHVFGLPRFLFILCASVLIIVGVIVCVLCAQFWFYRRHRGDKPYYNFSLLPQRGKEQFGLEDDDGGDDGETELFRSPIKRELSQRAHLVNNQTNYSFIIQAA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . * . . :* . * *. *.: :* *:*** * .:::: . * .* :.********.**:*:*: . * : . : .*:*:**:*::*::****: : **:* ** *: . ****.***::. . . **. *::.** : ****.*:***:******:*:* *. * :.** :*: ** .*:.*:*:*:.* .: :::* .******:**:: *****:** .**:*:*:********.:* * **:.*: :*: :.: ***::*:* : : :* : **.::.: : *.: *:: *** ** *.: . ** . : : *.:. : : : . . . : * .:.**.: ** ::: ::..*..:*****:****: * *:*:** .** * * *****:.*********:**** * :*: ..:*.* .:*.** **:*:: ******** * :** . ** *::. ********:: :.. :**. ***.* .*************.***:**: :.. . : *:*:*: :* **: :. * *:** :: *:* .****** **.* ********:.:.*:*:***:** *:* :* .:**::*..*:**:.*** *::*:* . . * * .*.: : :* . : ****:* :** :::*. . .* . .* * . :.: :. . . :. : .* :* : : ::. . : . . : .*. * : . . **:. . * * . : : *. .*:: * .::.. . : :* : : .. ::: *: :: ::.... : :. : :: : . ... ** : :: . :*. .. :.: . . :* :.:: : :: . : .: . * . *:. .* * .* : :. .. *.* .. ... : : .* . .. ..: *.* *: .:*: * : : :: . * * :. * .: . * : : :: : : *:. ::: :. :: :***** *.: :.. : . ::.. : . : :* .. :: *.:. . :.* .:: *:.* .: . :.::: . : ", "identical_positions": 346, "similar_positions": 433, "identity": "23.43%" }, { "cls_id": "homologset.agr.FB:FBgn0004654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52209-1", "uniprot_id": "6PGD_HUMAN", "id": "P52209-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKG--------TKVVG--AQSLKEMVSKLKKPRRIILLVKAG-------------QAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGAR-----------------------YGPSLMPGGNKEAWPHIKT---------IFQGIAAKVGTGEPCCDW--------------VGDEGAG-----HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDS----------------------FLIEITANILKFQ----------DTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIG----------------------EAVFARCLSSLKDERIQASKKLKGPQK--FQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLN------YGGIALMWRGGCIIRSVFLGKIK-DAFDRNPE-------------------------------------------------------------------LQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPG------------QFIHTNWTGHGGTVSSSSYNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCD0-1", "uniprot_id": "6PGD_MOUSE", "id": "Q9DCD0-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKG--------TKVVG--AQSLKDMVSKLKKPRRVILLVKAG-------------QAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGAR-----------------------YGPSLMPGGNKEAWPHIKA---------IFQAIAAKVGTGEPCCDW--------------VGDEGAG-----HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMRHEEMAQAFEEWNKTELDS----------------------FLIEITANILKYR----------DTDGKELLPKIRDSAGQKGTGKWTAISALEYGMPVTLIG----------------------EAVFARCLSSLKEERVQASQKLKGPKV--VQLEGSKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLN------YGGIALMWRGGCIIRSVFLGKIK-DAFERNPE-------------------------------------------------------------------LQNLLLDDFFKSAVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLTKPG------------EFIHTNWTGHGGSVSSSSYNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q883-1", "uniprot_id": "F1Q883_DANRE", "id": "F1Q883-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKFSRDRITAVKTLIETLIFERNQTSTMAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVHDFLNNEAKG--------TKVIG--AESLKDMVSKLKKPCRIILLVKAG-------------QAVDDFIDKLVPLLEPGDIIIDGGNSEYRDTTRRCKSLKEKNLLFVGSGVSGGEDGAR-----------------------YGPSLMPGGHKDAWPHLKD---------IFQSIAAKVGTGEPCCDW--------------VGDEGAG-----HFVKMVHNGIEYGDMQLICEAYHLMKDVLCMNHDEMAQVFEQWNKTELDS----------------------FLIEITANILKFK----------DADGTNLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIG----------------------EAVFARCLSSLKDERVQASKSLSGPQG--VKFTGNKAQFLEDIRKALYASKIISYAQGFMLLRQAALEFGWSLN------YGAIALMWRGGCIIRSVFLGKIK-EAFDRNPE-------------------------------------------------------------------LQSLLLDSFFSKAVQDCQDSWRRVVSTGVQQGIPMPSFTTALSFYDGYRHEMLPANLLQAQRDYFGAHTYELLSNPG------------TFIHTNWTGHGGKVSSSSYNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41572-1", "uniprot_id": "6PGD_DROME", "id": "P41572-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGQADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKD--------TKVIG--ADSLEDMVSKLKSPRKVMLLVKAG-------------SAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGEEGAR-----------------------HGPSLMPGGHEAAWPLIQP---------IFQAICAKAD-GEPCCEW--------------VGDGGAG-----HFVKMVHNGIEYGDMQLICEAYHIMQS-LGLSADQMADEFGKWNSAELDS----------------------FLIEITRDILKYK----------DGKG-YLLERIRDTAGQKGTGKWTAIAALQYGVPVTLIG----------------------EAVFSRCLSALKDERVQASSVLKGPST--KAQVANLTKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLN------YGGIALMWRGGCIIRSVFLGNIK-DAYTSQPE-------------------------------------------------------------------LSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEG------------QFHHTNWTGTGGNVSASTYQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38720-1", "uniprot_id": "6PGD1_YEAST", "id": "P38720-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS---ADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKG--------KSIIG--ATSIEDFISKLKRPRKVMLLVKAG-------------APVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGAR-----------------------YGPSLMPGGSEEAWPHIKN---------IFQSISAKSD-GEPCCEW--------------VGPAGAG-----HYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDS----------------------FLVEITRDILKFD----------DVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIG----------------------EAVFARCLSALKNERIRASKVLPGPEVP-KDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLN------NPAIALMWRGGCIIRSVFLGQIT-KAYREEPD-------------------------------------------------------------------LENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECAS-----DNLPVDKDIHINWTGHGGNVSSSTYQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53319-1", "uniprot_id": "6PGD2_YEAST", "id": "P53319-1", "name": "6-phosphogluconate dehydrogenase, decarboxylating 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKAVGDLGLVGLAVMGQNLILNAADHGFTVVAYNRTQSKVDRFLANEAKG--------KSIIG--ATSIEDLVAKLKKPRKIMLLIKAG-------------APVDTLIKELVPHLDKGDIIIDGGNSHFPDTNRRYEELTKQGILFVGSGVSGGEDGAR-----------------------FGPSLMPGGSAEAWPHIKN---------IFQSIAAKSN-GEPCCEW--------------VGPAGSG-----HYVKMVHNGIEYGDMQLICEAYDIMKRIGRFTDKEISEVFDKWNTGVLDS----------------------FLIEITRDILKFD----------DVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIG----------------------EAVFARCLSAIKDERKRASKLLAGPTVP-KDAIHDREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLN------NPAIALMWRGGCIIRSVFLAEIT-KAYRDDPD-------------------------------------------------------------------LENLLFNEFFASAVTKAQSGWRRTIALAATYGIPTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHTFRILPECAS-----AHLPVDKDIHINWTGHGGNISSSTYQA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O88658-1", "uniprot_id": "KIF1B_RAT", "id": "O88658-1", "name": "Kinesin-like protein KIF1B", "aln": "MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPEDPCFASQSRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEDMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDIDPLMDDYSGSGGKYLKDFQNNKHRYLLASENQRPGNFSTASMGSLTSSPSSCSLNSQAGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERNNTGEVIVTLEPCERSETYVNGKRVAHPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKREKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPVPPELLPTEMGKTHEDRPFPRTVVAVEVQDLKNGATHYWSLDKLKQRLDLMREMYDRAGEVGSNAQDDSETTMTGSDPFYDRFHWFKLVGSSPIFHGCVNERLADRTPSPTFSTADSDITELADEQQDAMEDFDDEAFVDDTGSDAGTEEGSELFSDGHDPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFPSAAMTRSGLSLEELRIVEGQGQSSEVISPPEEVNRMNDLDLKSGTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRHDEAFSTEPLKNNGRGSPLGFYHVQNIAVEVTESFVDYIKTKPIVFEVFGHYQQHPLHLQGQELNSPPQPSRRFFPPPMPLSRPVPATKLNTMNKTSLGQSMSKYDLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIRNKPEVDEAAVDAILSLNIISAKSLKSSHSSSRTFYRFEAVWDSSLHNSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRNLFGSGYSKSPDSNRVTGIYELSLCKMADTGSPGMQRRRRKVLDTSVAYVRGEENLAGWRPRGDSLILEHQWELEKLELLHEVEKTRHFLLLRERLGDSIPKSMSDSLSPSLSSGTLSTSTSISSQISTTTFESAITPSESSGYDSADIESLVDREKELATKCLQLLTHTFNREFSQVHGSISDCKLSDISPIGRDPSVSSFSSSTLTPSSTCPSLVDSRSSSMDQKTPEANSRASSPCQEFEQFQIIPTVETPYLARAGKNEFLNLVPDIEEVRAGSVVSKKGYLHFKEPLSSNWAKHFVVVRRPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMLKTPNTFAVCTKHRGVLLQALNDKDMNDWLYAFNPLLAGTIRSKLSRRCPSQPKY", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : ** *: : : :..*. : . : :: * .:.:. ::* :.::: : :: :: : * . : . . * *. .*. : :: : .: : : *: : * :* * :: ::*. .: *:: : * * :.*: : : . :: * ::: . : . *. * .: .: *: : * : : .:** *.: .:: .**:* * .:.:: . . ::. * .. : .:.::* :: .*.: : : .* :: :.: *.. * . * :: ..: .*: * .: .* .. . :: . .:. ::*: :: . : : : :: . :.: . * . : ::: *.:* .. . ", "identical_positions": 46, "similar_positions": 171, "identity": "2.53%" }, { "cls_id": "homologset.agr.FB:FBgn0004655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADT3-1", "uniprot_id": "D4ADT3_RAT", "id": "D4ADT3-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQ----------------------------KRPNFKPDIQEIPKKPKVEEED-TGDPFGFDSDDESLPVSSKSLAQGKGSSYSESSEAVQLEEVTSVLEANSKCSHAVGED------------SFASDRCLLVEDSLIGKEKNTNRIPEDNANKSSCTKLIT------SDKVENFSEEHEKNSHHFHKNAEDSTKKPNAETVAASECKADETKTS-DTWNSQSAKRTESPSESCPVKGSVRTGLYEWDNDFEDIRSEDCILSLDNDSLLEMKDEDLKNRIGGLENLNEAFEEDIIQSVLRPSNCRTYCRANK-------------AKSSQGTSNFDKLMDGTSQTLAKANSESSKDGLNQAKKGSVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPAD-----------LGEAGRLRKKADIATSKTTTRFRPSN---------------------------------TKSKKDVKLEFFGFEDHDETGGD--EGGSGSSNYKIKYFGFDDLSESEDDDDDDCQVERKKDKKRTKTAPSPS---------QQPPPESSDNSQDS-QSSTNNAENLDFTEDLPGVPESVKKPISKQGDK-----------------SKENTRKIFSGPKRSPTKAVYNARHWNH-----------------PDSEE-LPGPP---IVKPQ----------SVTVRLSSKEPN-QKDDGVFKAPAP-----PLKVIKTVTIPTQPYQEIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELE--QDASSAKLLNEKDMNKIKEKIRRLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRD----EDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIISSAKALQHCEDLIQQYNRAENSICIADSKPLPYQNVTNHVGKAVEDCMRAIIGVLLNLTNDN-----EWGSTKTGEQEGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCS-FDSSFSSGEGDHNLRLAG-----------------QVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQ-----HDKSGEWQETSGEIQWVSTEKTDGAEEKQKKEDEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQES-------------------PINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q65Z40-1", "uniprot_id": "WAPL_MOUSE", "id": "Q65Z40-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQ----------------------------KRPNFKPDIQEIPKKPKVEEED-TGDPFGFDSDDESLPVSSKNLAQGKGSSYSESSEAAQLEEVTSVFEANSKCSHVVGED------------SFASDRCLLVEDTLIGKEKSISRIPEDNANKSSCTKLLT------SDKVENFSEEHEKNSHHFHKNAEDSTKKPNAETAVASEYKADETKETNDTWNSQSGKRTESPSESCPVKGSVRTGLYEWDNDFEDIRSEDCILSLDNESLLEMKDEDLKNRIGGLENLNETFEEDIIQSVLRPSNCRTYCRANK-------------ARSSQGASNFDKLMDGTSQSLAKANSESSKDGLNQAKKGSASCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPAD-----------LGEAGRLRKKADIATSKTTTRFRPSN---------------------------------TKSKKDVKLEFFGFEDHDETGGD--EGGSGSSNYKIKYFGFDDLSESEDDDDDDCQVERKKDKKRTKTAPSPS---------QQPPPESSDNSQDS-QSSTNNAENLDFTEDLPGVPESVKKPISKQGDK-----------------SKENTRKIFSGPKRSPTKAVYNARHWNH-----------------PDSEE-LPGPP---IAKPQ----------RVTVRLSSKEPN-QKDDGVFKAPAP-----PLKVIKTVTIPTQPYQEIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELE--QDASSAKLLNEKDMNKIKEKIRRLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDD---EDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIISSAKALQHCEDLIQQYNRAENSICVADSNPLPYQNVTNHVGKAVEDCMRAIIGVLLNLTNDN-----EWGSTKTGEQEGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMQTSCS-FDSSFSSGEGDHSLRLAG-----------------QVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQ-----HDKSGEWQETSGEIQWVSTEKTDGAEEKQKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQES-------------------PINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5K2-1", "uniprot_id": "WAPL_HUMAN", "id": "Q7Z5K2-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQ----------------------------KRPNFKPDIQEIPKKPKVEEES-TGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHVVVED------------TVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLIT------SDKVENFHEEHEKNSHHIHKNADDSTKKPNAETTVASEIKETN-----DTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSLDSDPLLEMKDDDFKNR---LENLNEAIEEDIVQSVLRPTNCRTYCRANK-------------TKSSQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPAD-----------LGEAGRLRKKADIATSKTTTRFRPSN---------------------------------TKSKKDVKLEFFGFEDH-ETGGD--EGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPS---------LQPPPESNDNSQDS-QSGTNNAENLDFTEDLPGVPESVKKPINKQGDK-----------------SKENTRKIFSGPKRSPTKAVYNARHWNH-----------------PDSEE-LPGPP---VVKPQ----------SVTVRLSSKEPN-QKDDGVFKAPAP-----PSKVIKTVTIPTQPYQDIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELE--QDASSAKLLNEKDMNKIKEKIRRLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRD----EDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNRAEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDN-----EWGSTKTGEQDGLIGTALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCS-FDSSICSGEGDDSLRIGG-----------------QVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQ-----HDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQES-------------------PINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDM0-1", "uniprot_id": "A0A8N7TDM0_DANRE", "id": "A0A8N7TDM0-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFSKTYTRKG--------------------GEASSKFDEVFSNKKATLTTKWGESTYKAHLGI----------------------------KRPSFKPDVSELTKRPRFDDDDSSEDPFGFDSDDESKTVTSRDTAQS--EMDSDTAGP---------------KNEQLKTQ------------TEKPSRGTLVTS----TSSLGSSTNISRG---AVGVNSP------AKTS--PASSYVTGTVGTWSKSNVTVSKQLSQVSSLKTPSRGIS----NDWDSFGEDSPPGAG--------EGSSTQTSNSSDELKSAEQCPAEPEP-PVEQPVDFEQLPL------LKPS-----SDRVYRRPRGKETESSAA-------------GDTIP-AVSSVSAPAPVMSSNAGVAGSS---------------GVKPPAGRGRVRDYTVLHPSCVSVCNVTIQDSIERSVDDFVMPVQAD-----------IGEAGTFRRKADTQ-APKPTRFRPTQ---------------------------------SKSKKETKLEFFGFEENEAQDADGDATGSGSTSYKIKYFGFDDLSESDSEDDDDSAARERKK-NKKAEAEALS------TGTGSP---QFSDSQESQQSQSSLSTDSQESLDETGATGSQKERHRKQSNK-----------------SKEIGRKIFSGPKKSPAKAVYNARHWNQ-----------------PESEE-VPTPASHTVAVPKPSA-------SSSSTSSSKDTNSHKDDGVFKAPPP-----PPKVIKSVTIPTELNQDIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEHKELYTVVQHVKHFNDVVEFGENQEFTDDFEYLETGLKSTQPLNTRCLSIISLATRCAMPSFRMHLRARGKVAQVFKMLSDAQQHPNMALCTASLMYILSRDRLNMDLDRSCLELMIRLLEME--QDDSVADQLTAKEMSKVKEKIRKLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVENLNKE----EDKESLVASLWGAERCLRVLESVTVHNPENQAYLIAYKDSQLIMSSARALQHCEQMIQRYSREVS---SSSSSTLPQSSHSN-VGKAVEDCMRAVIGVLLNLTHDN-----EWGSTKTGEQDGLILTALDCVLKVPRYLPQEQRFDIRVLGLGLLINLVEYSARNRECLVEMEVDMSYLMEAEAVVKMENDVKTEEQKRDQMEEEEKRKATLKSLNALAALVQLFLERERAAVLAEAQTDDLISEAPKSQ-----ADQSGEWQETSGEIQWVASETND-TNDK--KEEEEEELDLNKALQHAGKHMEDSIVASYSALLLGCLCQGS-------------------PMNVKTVRENLPKGDFSIMTEMLKKFLNFMNLTCSVGTTGQKSISRVIDYLEHC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QEL9-1", "uniprot_id": "A0A8M9QEL9_DANRE", "id": "A0A8M9QEL9-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GDGTSKFDEVLSNKRAMLSTKWGETTYKAKVGA----------------------------KRPGLKTEVTDQTKRSKVSEGDGSEDPFGFDSDDESKPVTSRNIAQSKAKVTSSTGGSQ----ASLTLEPNSRVNQPASVE------------AVAPSRASFSLS----SERSAHKVPEDPGK--YFNTSTT------GKTPSWPAESTDRHSYSWYKNPSECDTRPLAQTTTLKSEKTEDK----DSYDAWSAVVGLGARSTSLFTAPKESSSMLWASSSYSHSNIQGKSSTET-RLDNFHQGEFNVP------VEPSESEDHSQSVLRAPNCRTYCRPNK-------------GKQPGGADGSGSASSHISTGVLQTIGTD---------------NASKTTNRGRTRDFTVLHPSCVSMFNVTFQDSMDRSVEEYTASTQASG----------PGDEGRLKKKTETE-SKPLSRSRPTQ---------------------------------SKMK-SSKLELFGFDDTDAVADD-DDSASGSSSYRIKYFGFDDLSESDSEEEEGSSHRRRAKRMAAAEAEPLLS---IDTNVDSPPPREMQSSHSSYTAGHSLKHDPLEFPDIPFPFETVRKPQVKAQEK-----------------AKES-RRIFSGPKKSPTKAVYNARHWNQ-----------------PEAEEMLPMPPSRSQAPP------------AAASGGSKESNSHKDDGVFKAPAP-----PPKVIKSVTIPTEPYQDMVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEHKELYTVVQHVKHFNDVVEFGENQEFTDDFEYLATGLKTGQPLNTRCLSVISLATRCAMPSFRMHLRARGKVAQVFKTLGDAPQHSNLALCTASLMYILSRDRLNMDLDRASLDLMIRLLELE--QDKSIADQLTTKEMNKVKEKIRKLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVENLSRE----DDKENLVASLWGAERCLRVLESVTVHNPENQGYLIAYKDSQLIVSSAKALRHCEEMIQRYSREMN---RGLCTTLPFCSNSN-VGKAVEDCMRAIIGVLLNLTHDN-----EWGSTKTGEQDDLITTALNCVLKVPQYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVELQMEGGEVWDSMCVSDKD-ELQTER-----------------SHSAIAALVKLFLQREHAAMLAEAETDDFINDAPKPQ-----LDQSGEWKETNEEIQWVASENNS-TEEKKKKEEDDEELDLNKALQHAGKHMEDSIVASYTALLLGCLCQGS-------------------PMNVTTVRENLPKGDFSVMTEMLKKFLNFMNLTCDVGTTGQKSISRVIDYLEHC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W517-1", "uniprot_id": "WAPL_DROME", "id": "Q9W517-1", "name": "Protein wings apart-like", "aln": "MSRWGKNIVVPLDSLCKEKENTNRPTVARSVGTVGKWGKMGFTSTRTYTLPAIHPMAAAAAAAAAAASPSQSPASTQDHDPNDLSVSVPEPPKPKKFFKSRNTAPPEVIAQIIQQLPHCGAGASPMRDHFSSAGAGAGGLTPTSGAQEAGGVKLKPGKGASSAERKRKSPKKKAATTSASTPSTPGAFYGASDRDGDGLSDPASEQPEQPSSASGKQKQKKPKEEKKLKPEAPPSRVLGRARKAVNYREVDEDERYPTPTKDLIIPKAGRQPAEVAATATLAAASSEAFISSTFGSPGSEPSLPPPTSAPSASASTSSQLPSASGSASNPPSASRTPEHPPIVLRISKGTSRLVSTDSEEPPSSSPAHQNQLNQLSVTEEEPAERSGDETVPASTPKITVKPLRPPTAADSVDGSSAAVGGASAGDSFEERKSQSLEPNEDEEEEEEEEDEEEEPPEINYCTVKISPDKPPKERLKLIIKTDVIRNAIAKAAAAAESRSEKKSRSKKHKHKQLLAAGSGAAPASGATPAEINSEFKTPSPHLALSEANSQQAQHTPSHLHQLHQLHPQRGSAVISPTTRSDHDFDSQSSVLGSISSKGNSTPQLLAQAVQEDSCVIRSRGSSVITSDLETSQHSSLVAPPSDIESRLESMMMTIDGAGTGAASAVPETPLQEDILAVLRGEVPRLNGNTDPEPTEEEDQQQQPKRATRGRGRKANNNVDVTPPATETRTRGRAKGADATTAAISPPTGKRNTRGTRGSRKAEQEVDMEVDETAMTTVPANEEQLEQATLPPRRGRNAAARANNNNLASVNNNINKIAANLSAKAEASRLAEGGVAGGAARSYGRKRKNQQVTQVLQQEPVPEEQETPDAEEEQPTPAKIPHTDHREHSPDHDPDPDPDELSNNSNNSSLQHDGSSSSPPPRDFKFKDKFKRTLTLDTQGAANAGAGGAAAAAPPESSGEQRGAVKLVISKKKGSIFKSRALVPSDQAEQATVAKRHLYKHSWDAALEANGGGTNSDASNASASGVGVAGAKDHLHHLAAGKSDGDFGDSPSSNNNGSSSACSSASTLRGDSPALGKISRLAGKQGVPATSTSSDAFDLDLEPIAGELDLERSAAGASAGGTGATTGGGGATGGGGPVRVDRKTKDYYPVVRNVKTAHQIQEIGEYQEMDDDVEYILDALQPHNPPATRCLSALQLAAKCMMPAFRMHVRAHGVVTKFFKALSDANKDLSLGLCTSAIMYILSQEGLNMDLDRDSLELMINLLEADGVGGSTETGHPDRAGYDRNKQKVRELCEEIKAQGKGTHLNVDSLTVGTLAMETLLSLTSKRAGEWFKEDLRKLGGLEHIIKTISDFCRPVIACDTEIDWQPTLLDNMQTVARCLRVLENVTQHNETNQRYMLTSGQGKAVETLCQLYRLCSRQIMLHPSDGG------------GSNKEHPGVAMRELLVPVLKVLINLTHTFNEAQPSLGAELLGQRGDVVETSFRLLLLSANYIPDQCVFELSILVLTLLINLCMHTVPNRAALMQAAAPAEYVADNPPAQGSVSALQALLEYFYK---------CEELARLVEKNTDAFLESNEKGKKKQEEVEETVNNLVQRAGHHMEHTLKGSYAAILVGNLIADNELYESVVRRQLRGNSFKEIIGVLEKYHTFMNLTSSLEAAFVAHMKSTKRIIDNFKKRDYIYEHSDEHDNPLPLNLETTAQVLAVGADASHAATSSTTVGSGSAPSSTSATGTTRAPRVYKTYSSHR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:*..: : * * .::: .. .:*:: :: :* * * *:* : .: . .:. . : .:** ...::. . . : : .. . . . .. . . : :. . . . . : . : : . :: . . . : *. :*: *: * :. *.:: *:.. .. . * .:: : : *.. .: * : : . :. . :::. : : . : . . . . . . : . : : . :: : :: :* :: .* . : *. :: *: *::** * *. . ...: . :.** .:*.* *. :::*: *: : : .:: :: *: *.**::** ::: *:** **: **.**: .*:. :* ***** :.**::* **:****:**:* *: .** *.*: :. .:.***:::*****:: ******* .*:***.*** : . : : .: *:*:*.*** :: .**:::.:*.* ***************:****:** ****:**:..:.: : : : .*: .: . *******.** ** ** *::: :.: : : .: : *. * : . . .: * *:.: : .:: **:***: . *: *:: .:: *:: :* ..*:*:: *:: :* * ***** ::. ** .*:: . . :: : .. **: :. . : :.:: :.: .*.: . .* . . : : :. :*: *: :: ..: *:: * : . . *:*: *. : *. * : : .. :. . .. ..:** . .** . . ", "identical_positions": 193, "similar_positions": 348, "identity": "10.95%" }, { "cls_id": "homologset.agr.FB:FBgn0004656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWU1-1", "uniprot_id": "D3ZWU1_RAT", "id": "D3ZWU1-1", "name": "", "aln": "----------------------------MSTTTAAAP------------TGIPAVPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKP--------------------------------------------------AAG-----------------------------------AQNAGAQQMGAVSSVSPAPPFQNIPPTVSQTP--------------------------------------VIAATPVPT---------------ITANVTSVPVPPPAAPPPPATPIVPV------------------VPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS----EPKQAKVVARRESGGRPIKPP-KKDLE--------DGEVPQHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEVPALPAPTAP-------------------------IVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKK--KKDKEK--EKEKHKAKSEEEKKAKAAP-----------------------------------------------------------------------------------------------------------------------AAKQAQQKKAPTKKAN------------------------------------STTTASRQLKKGGKQAS---------------------------ASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKK-QRKPLSTSGKKQAAKSKEELAQEKKKELEKRLQDVSGQLNS-KKPTKK---------------EKSGSAPSGGPSRLS-SSSSS---------------ESASSSSSGSSSDSSDSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2F0-1", "uniprot_id": "BRD3_MOUSE", "id": "Q8K2F0-1", "name": "Bromodomain-containing protein 3", "aln": "-----------------------------MSTTAAAP------------TGIPAVPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKP--------------------------------------------------AAG-----------------------------------AQNAGSQQVAAVSSVSPATPFQNIPPTVSQTP--------------------------------------VIAATPVPT---------------ITANVTSVPVPPPAAPPPPATPIVPV------------------VPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS----EPKQAKVVARRESGGRPIKPP-KKDLE--------DGEVPQHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEAPALPAPTAP-------------------------IVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKK--KKDKDKDKEKEKHKAKSEEEKKAKAAP-----------------------------------------------------------------------------------------------------------------------AAKQAQQKKAPTKKAN------------------------------------STTTASRQLKKGGKQAS---------------------------ASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKK-QRKPLSTSGKKQAAKSKEELAQEKKKELEKRLQDVSGQLNS-KKPTKK---------------EKSGSAPSGGPSRLS-SSSSS---------------ESASSSSSGSSSDSSDSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15059-1", "uniprot_id": "BRD3_HUMAN", "id": "Q15059-1", "name": "Bromodomain-containing protein 3", "aln": "----------------------------MSTATTVAP------------AGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKP--------------------------------------------------AAG-----------------------------------AQSAGTQQVAAVSSVSPATPFQSVPPTVSQTP--------------------------------------VIAATPVPT---------------ITANVTSVPVPPAAAPPPPATPIVPV------------------VPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS----DPKQAKVVARRESGGRPIKPP-KKDLE--------DGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAP-------------------------MVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKK--KKDKEK--EKEKHKVKAEEEKKAKVAP-----------------------------------------------------------------------------------------------------------------------PAKQAQQKKAPAKKAN------------------------------------STTTAGRQLKKGGKQAS---------------------------ASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKK-QRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARK---------------EKPGSAPSGGPSRLS-SSSSS---------------ESGSSSSSGSSSDSSDSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUX3-1", "uniprot_id": "A0AB32TUX3_DANRE", "id": "A0AB32TUX3-1", "name": "", "aln": "------------------------------MSAVTSP------------AQVPAP--IVNPPPPEFINSGKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPPPKGKARKP--------------------------------------------------GAP-----------------------------------PGSE-NQQSIALTPGSPSSSCPSSPPQLAQTP--------------------------------------VIAATPVAT---------------ITTNVQAA---------PPATAMIPT------------------AQP----VVKKGVKRKADTTTPTTCAITASRSESPTAML----ESKHSKVISRRESTGRPIKPP-KKDLE--------DGDVQQPGNKKSKLNDHLKYCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAKMPDEPAEPSSPNAVSATA------------------------VVSKSTGSSESSADSSSSS--SDSEEERATRLAELQEQLKAVHEQLAALSQGPVSKPKKKKEKKEKEKK--KKDKEK--DKDKNKVKAEEDKKAKSTQ-----------------------------------------------------------------------------------------------------------------------PNKQTPQKKTSARKPN------------------------------------STSTT-RQAKKGGKPGA---------------------------ANYESDEEE-SLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKK-QRKPLPGTGKK-SAKSKEELVQEKKKELEKRLQDVSGQLNNNKKPPKKA--------------EKAGSAQGGGASRLSGSSSSS---------------DSGSSSSSGSSSESSDSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JJ13-1", "uniprot_id": "BRD2_MOUSE", "id": "Q7JJ13-1", "name": "Bromodomain-containing protein 2", "aln": "MLQNVTPH-KLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKG-------------------------------------------AKLAALQGS-----------------------------------ITSAHQVPAVSSVSHTALYTPPPEIPTTVLNIP------------------------------------HPSVISSPLLK---------------SLHSAG-----------PPLLAVSAA-------------------PPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGS---LEPKAARLPPMRRESGRPIKPP-RKDLP--------DSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLTKSSSESSSEES------SSESSSEEEEEEEEDEDEEE-SESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKK-------KRKAEKHRGRIGIDEDDKGPRAP----------------------------------------------------------------------------------------------------------------------RPPQPKKSKKAGGGGSNATTLSH---------------------PGFG----TSGGSSNKLPKKSQKTAP-----------------------PVLPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKK-PRKPYTI--RKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKAS-----------EKTESS-AQQVAVSRLSASSSSS---------------DSSSSSSSSSSSDTSDSDSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MGA9-1", "uniprot_id": "BRD2_RAT", "id": "Q6MGA9-1", "name": "Bromodomain-containing protein 2", "aln": "MLQNVTPH-KLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKG-------------------------------------------AKLAALQGS-----------------------------------ITSAHQVPAVSSVSHTALYTPPPEIPTTVLNIP------------------------------------HPSVISSPLLK---------------SLHSAG-----------PPLLAVSAA-------------------PPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGS---LEPKAARLPPMRRESGRPIKPP-RKDLP--------DSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLAKSSSESSSEES------SSESSSEEEEEEDEEDEEEE-SESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKK-------KRKAEKHRGRIGIDEDDKGPRAP----------------------------------------------------------------------------------------------------------------------RPLQPKKSKKAGGGGSNATTLSH---------------------PGFG----TSAGSSNKLPKKAQKTAP-----------------------PVLPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKK-PRKPYTI--RKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKAS-----------EKTESS-AQQVAVSRLSASSSSS---------------DSSSSSSSSSSSDTSDSDSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25440-1", "uniprot_id": "BRD2_HUMAN", "id": "P25440-1", "name": "Bromodomain-containing protein 2", "aln": "MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKG-------------------------------------------AKLAALQGS-----------------------------------VTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIP------------------------------------HPSVISSPLLK---------------SLHSAG-----------PPLLAVTAA-------------------PPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGS---LEPKAARLPPMRRESGRPIKPP-RKDLP--------DSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEES------SSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKK-------KRKAEKHRGRAGADEDDKGPRAP----------------------------------------------------------------------------------------------------------------------RPPQPKKSKKASGSGGGSAALGP---------------------SGFG----PSGGSGTKLPKKATKTAP-----------------------PALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKK-PRKPYTI--KKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKAN-----------EKTESSSAQQVAVSRLSASSSSS---------------DSSSSSSSSSSSDTSDSDSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13709-1", "uniprot_id": "FSH_DROME", "id": "P13709-1", "name": "Homeotic protein female sterile", "aln": "------------------------------MSSSEPPPRYE----PPVEPVNGIVQPPVIPP------AERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKVSVAASSAQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPISTMPPHTVPGSTNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAVNSSSLLDGSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDAVIPPQQPAKIKKGVKRKADTTTPTANAFESPYTQMDSKSAKIATRRESNRQDLTFQGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDTENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKK-THK-------KPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDE-----------SASSKVEAVQPANPVSSSSSSSD---------------SSSSSSSDSSSSDSSDSEAGDGDERPPRKKKSRDSNGSNVNNPSINVVMGGNLPSGALSPTTMLMGLDHVVNSNTPTSQMSNMLGNANPLTAAAMLNNNNKTSLPGSNFGGAPAPGNMMHAGAGVPVAGAAVSASTGQQHNKNGPNDLSKVQPGGPINAALPPHSFAGGTATVATSQSSGGIRIASNLHKPSGLGGGDLGEHHAALAAALTSGINSTGTAGGGINNNGGSNNNANPLGGSHGDAMVNASLASLASGLKQIPQFDDPVEQSLASLEFSAGSTGKSGLTDNFLMQQHLMQPAGPQQQQQQQQQQPFGHQQQQQQQQQQQQQQQQHMDYVTELLSKGAENVGGMNGNHLLNFNLDMAAAYQQKHPQQQQQQAHNNGFNVADFGMAGFDGLNMTAASFLDLEPSLQQQQMQQMQLQQQHHQQQQQQTHQQQQQHQQQHHQQQQQQQLTQQQLQQQQQQQQQQQHLQQQQHQQQHHQAANKLLIIPKPIESMMPSPPDKQQLQQHQKVLPPQQSPSDMKLHPNAAAAAAVASAQAKLVQTFKANEQNLKNASSWSSLASANSPQSHTSSSSSSSKAKPAMDSFQQFRNKAKERDRLKLLEAAEKEKKNQKEAAEKEQQRKHHKSSSSSLTSAAVAQAAAIAAATAAAAVTLGAAAAAALASSASNPSGGSSSGGAGSTSQQAITGDRDRDRDRERERERSGSGGGQSGNGNNSSNSANSNGPGSAGSGGSGGGGGSGPASAGGPNSGGGGTANSNSGGGGGGGGPALLNAGSNSNSGVGSGGAASSNSNSSVGGIVGSGGPGSNSQGSSGGGGGGPASGGGMGSGAIDYGQQVAVLTQVAANAQAQHVAAAVAAQAILAASPLGAMESGRKSVHDAQPQISRVEDIKASPGGQGQSSPAQQSPQDRAAAKRAEQRRAEQERRRREALAGQIDMNMQSDLMAAFEETL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q91Y44-1", "uniprot_id": "BRDT_MOUSE", "id": "Q91Y44-1", "name": "Bromodomain testis-specific protein", "aln": "------------------------------MSLPSRQ------------------TAIVNPPPPEYINTKKSGRLTNQLQFLQRVVLKALWKHGFSWPFQQPVDAVKLKLPDYYTIIKTPMDLNTIKKRLENKYYEKASECIEDFNTMFSNCYLYNKTGDDIVVMAQALEKLFMQKLSQMPQEEQ---VVGGKERIKKD---------------------------------------------------------------------------------------------IQQKIAVSSAKEQIPSKAAENVFKRQE----------------------------------------IPSGLPD--------------ISLSPLN----------MAQEAPPICD--------------------SQSLVQITKGVKRRADTTTPTTSIAKAS-SESPPTLR-----ETKPVNMPVKENTVKNVLPD---------------SQQQHKVLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDADALGLHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVVAMARTLQDVFELHFAKIPDEPIESMHACHLTTN--------------------------SAQALSRESSSEASSGDASSEDSEDERVQHLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAPK-------------RKKVNNRDENPRKKPK-------------------------------------------------------------------------------------------------------------------------QMKQKEKAKI----------------------------------------------NQPKKKKP-------------------------------LLKSEEEDNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQSREPSLRNSNPDEIEIDFETLKASTLRELEKYVLACLRKR-SLKP----QAKKVVRSKEELHSEKKLELERRLLDVNNQLNCRKRQTKRPAKVEKPPPPPPPPPPPPPPPELASGSRLTDSSSSSGSGSGSSSSSSGSSSSSSSSGSASSSSDSSSSDSSDSEPEIFPKFTGVKQNDLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKENIK----------------------------------------------------------------------QIQSSVQDITSAEAPLAQQSTAPCGAPGKHSQQMLGCQVTQHLQATENTASVQTQPLSGDCKRVLLGPPVVHTSAES---------------------------------------LTVLEPECHAPAQKDIKIKNADSWKSLG---------KPVKASSVLKSSDELFNQFR---------------KAAIEKEVKARTQEQMRKHLEHNAKDPKVSQENQREPGSGLTLE---------------SLSSKVQDKSLEEDQSEQQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPSEAQDVSKLWLLKDRNLAREKEQERRRREAMAGTIDMTLQSDIMTMFENNFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7T3-1", "uniprot_id": "BRDT_RAT", "id": "D4A7T3-1", "name": "Bromodomain testis-specific protein", "aln": "------------------------------MSLPSRQ------------------MAIVNPPPPEYINAKKTGRLTNQLQFLQRVVLKALWKHSFSWPFQQPVDAAKLKLPDYYTIIETPMDLSTIKKRLENRYYEKASECVGDFNTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMPQEEQ---IVGGKERMKKD---------------------------------------------------------------------------------------------IQQKTAVSSAKEQTPSKSAENVFKRQE----------------------------------------IPAGFPD--------------VCLSPLN----------MAQEAPPTCD--------------------SQTVVQITKGVKRRADTTTPTTSSAKAS-SESPPPLR-----EAKPANAPVKENTVKSVLPD---------------SQQQHRVLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDVDALGLHNYYDIVKNPMDLGTIKGKMDKQEYKDACEFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFEMHFAKIPDEPVESMRACHLTTN--------------------------SAKALSRESSSEASSGDCSSEDSEDERVQRLAKLQEQLNAVHQQLQVLSQVPLRKLKKKNEKSKRAPK-------------RKKVN-RDENPKKKAK-------------------------------------------------------------------------------------------------------------------------QMKQKEKAKS----------------------------------------------NQPKKKKP-------------------------------LLKLEEEDNAKPMNYDEKRQLSLDINKLPGDKLGRIVHIIQSREPSLRNSNPDEIEIDFETLKASTLRELEKYVLACLRKR-SLKP----HAKKVVRSKEELHSEKKLELERRLLDVNNQLNCRKRQTKRPAKVAVSPRPPLPPPPPPPP-ELASGSRLSDSSSSS-----SSSGSGSSSSSSSSSGSGSSSSDSSSSDSSDSEPEISPKFTGVKQNDLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKENTK----------------------------------------------------------------------QIQCSVPDITSAETALVQQSTGPCGAPGKPPQQMPGCQVPHHLQATESTASVQTQPLAGDCKRVLHGPPVVHASAES---------------------------------------HTVLELQCHAPVQKDIKIKNADSWKSLG---------KPVKASSVLKSSDELFNQFR---------------KAAIEKEVKARTQEQIRKHLEHSAKDPKVSQESQREFGSGFTPE---------------SSSNKVQGRSHGEEQSEQQQLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPSETQDISKLWLLKDRNLAREKEQERRRREAMAGTIDMTLQSDIMTMFENNFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q58F21-1", "uniprot_id": "BRDT_HUMAN", "id": "Q58F21-1", "name": "Bromodomain testis-specific protein", "aln": "------------------------------MSLPSRQT-----------------AIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ---VVGVKERIKKG---------------------------------------------------------------------------------------------TQQNIAVSSAKEKSSPSATEKVFKQQE----------------------------------------IPSVFPK--------------TSISPLN----------VVQGASVNSS--------------------SQTAAQVTKGVKRKADTTTPATSAVKAS-SEFSPTFT-----EKSVALPPIKENMPKNVLPD---------------SQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPLCYIKTD--------------------------ITETTGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKK-------------KEKVNNSNENPRKMCE-------------------------------------------------------------------------------------------------------------------------QMRLKEKSKR----------------------------------------------NQPKKRKQQFI----------------------------GLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKR-PLKP----PAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTK--------------SDKTQPSKAVENVSRLSESSSSS----------------SSSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKENVKKMKNECIP------------------------------------------------------PEGRTGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGDSD--------------------------------------TTMLESECQAPVQKDIKIKNADSWKSLG---------KPVKPSGVMKSSDELFNQFR---------------KAAIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTVE---------------SFSNKIQNKCSGEEQKEHQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSSEAQDKSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESU6-1", "uniprot_id": "BRD4_MOUSE", "id": "Q9ESU6-1", "name": "Bromodomain-containing protein 4", "aln": "-----MSTESGPGTRLRNLPVMGDGLETSQMSTTQAQAQ-----------PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGR---------------------------------------------------------------------------------------KETGAAKPGVSTVPNTTQASTSPQTQTPQQNPPPP-----------------------------------VQATTHPFPAVTPDLIAQPPVMTMVPPQPLQTPSPVPPQPPPPPAPVPQPVQSHPP-----------IIATTPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLAPEPK-------TAKLGPRRESS-RPVKPP-KKDVP--------DSQQHPGPEKSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP-------------------TKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKK----------EKHKKKEEVEENKKSKTKE------------------------------------------------------------------------------------------------------------------------LPPKKTKKNNSSNSN---------------------------------------VSKKEPVPTKTKPP---------------------------PTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESTSESSSSDSEDSETEMAPKSKKKG----------HTGRDQKKHHHHHHPQMQPAPAPVP------------QQPPPPPQQPPPPPPPQQQQQQPPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN-------------------------------------------------QHAVVSPPALHNALPQQPSRPSNRAAALPPKPTRPPAVSPALAQPPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQPQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPPGQQPTHPPPGQQPPPPQPAKPQQVIQHHPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKKQVKGRAEPQPPGPVMGQGQGCPPASPAAVPMLSQELRPPSVVQPQPLVVVKEEKIHSPIIRSEPFSTSLRPEPPKHPENIKAPVHLPQRPEMKPVDIGRPVIRPPEQSAPPP-----------------------------GAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQK-------HPTTPSSTAKSSSDSFEHFR---------------RAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQQQQRQEQQQQQQQAAAVAAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60885-1", "uniprot_id": "BRD4_HUMAN", "id": "O60885-1", "name": "Bromodomain-containing protein 4", "aln": "-----MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQ-----------PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGR---------------------------------------------------------------------------------------KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPP------------------------------------VQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-----------IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPK-------TTKLGQRRESS-RPVKPP-KKDVP--------DSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPP-------------------TKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKK----------EKHKRKEEVEENKKSKAKE------------------------------------------------------------------------------------------------------------------------PPPKKTKKNNSSNSN---------------------------------------VSKKEPAPMKSKPP---------------------------PTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKG----------HPGREQKKHHHHHHQQMQQAPAPVP------------QQPPPPPQQPPPPPPPQQQQQ-PPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN-------------------------------------------------QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ-LQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK---------------------------------QELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPP-----------------------------GAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQK-------HPTTPSSTAKSSSDSFEQFR---------------RAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQE--QQQQQQQQAAAVAAAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** . : * *****:: ..*:* :*** *:*** **** ** ****:.:*: ***:.***:****.** * * : ******.***:***. :*:*:**::***:*:**: .:* ** * : .:. . . . .*****:******:. . . . : * :. *:.: *: *. **:*:::*** ******:***.. * **:* :::*:***:.*:* *:: ::* .* *.**:**:* **********:**:*.* ****** :::::* ** . . .. .:*::** :* *:.:* .::::: **: * : *.: .:. : . . . ::*: **.*:*******:**:***:****:***** ***** :***:**********.:****** ** :**:*: : * :.: * * .. .: :.:. . .. . ... ...: ", "identical_positions": 207, "similar_positions": 153, "identity": "9.8%" }, { "cls_id": "homologset.agr.FB:FBgn0004657", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49134-1", "uniprot_id": "ITB1_RAT", "id": "P49134-1", "name": "Integrin beta-1", "aln": "----------MNLQLVFWIGL----------ISLICS----------------VFGQTDKNRCLKANAKS-------CGECIQAGPNCGWCTNTTFLQEG---MPTSARCDDLEALK-----------------------------KKGCHPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLLLKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTP-AKLRNPCT---SEQNCTSPFSYKNVLSLTDRGEFFNELVGQQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTR-LLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLEN-NVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGEN---GRKCSNISIGDEVQFEISITANKCPN--KESENQLKLNPLGFTEEVEVVLQFICKCNCQ---SHGIPASPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSE-DMDAYCRKE-NSSEICSNNGECVCGQCVCRKRENTNEIYSGKFCECDNFNCDRSNGLICGG--NGVCRCRVCECYPNYTGSACDCSLDTVPCVATNG-QICNGRGICECGACKCTDP---KFQGPTCETCQTCLGVCAE-HKECVQCRAFNKGEKK--DTCAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYS-VNSKGEAHVHVVETPDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKS--AVTTVV--------NPKYEGK--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09055-1", "uniprot_id": "ITB1_MOUSE", "id": "P09055-1", "name": "Integrin beta-1", "aln": "----------MNLQLVSWIGL----------ISLICS----------------VFGQTDKNRCLKANAKS-------CGECIQAGPNCGWCTNTTFLQEG---MPTSARCDDLEALK-----------------------------KKGCQPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLLLKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTP-AKLRNPCT---SEQNCTSPFSYKNVLSLTDRGEFFNELVGQQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTR-LLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLEN-NVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGEN---GRKCSNISIGDEVQFEISITANKCPN--KESE-TIKIKPLGFTEEVEVVLQFICKCNCQ---SHGIPASPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSE-DMDAYCRKE-NSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGG--NGVCRCRVCECYPNYTGSACDCSLDTGPCLASNG-QICNGRGICECGACKCTDP---KFQGPTCETCQTCLGVCAE-HKECVQCRAFNKGEKK--DTCAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYS-VNGNNEAIVHVVETPDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKS--AVTTVV--------NPKYEGK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05556-1", "uniprot_id": "ITB1_HUMAN", "id": "P05556-1", "name": "Integrin beta-1", "aln": "----------MNLQPIFWIGL----------ISSVCC----------------VFAQTDENRCLKANAKS-------CGECIQAGPNCGWCTNSTFLQEG---MPTSARCDDLEALK-----------------------------KKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTP-AKLRNPCT---SEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTR-LLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLEN-NMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGEN---GRKCSNISIGDEVQFEISITSNKCPK--KDSD-SFKIRPLGFTEEVEVILQYICECECQ---SEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSE-DMDAYCRKE-NSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGG--NGVCKCRVCECNPNYTGSACDCSLDTSTCEASNG-QICNGRGICECGVCKCTDP---KFQGQTCEMCQTCLGVCAE-HKECVQCRAFNKGEKK--DTCTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYS-VNGNNEVMVHVVENPECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKS--AVTTVV--------NPKYEGK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YW86-1", "uniprot_id": "A0A8M6YW86_DANRE", "id": "A0A8M6YW86-1", "name": "Integrin beta", "aln": "----------MDLKLLFISAL----------LGIISC----------------SHAQQEGNECIKANALS-------CGECIQVGDKCGWCTDAEFLKQG---EPTSARCDELESLK-----------------------------KRGCAEDKIENPHGSQRILKNTPVTNRKKG-AEKLRPEDITQIQPQKLSLQLRSGEPQNIKLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKNLGTSLMKEMSKITSDFRIGFGSFVEKTVMPYISTTP-AKLLNPCT---GDQNCTSPFSYKNVLKLTSNGQRFNSLVGQQQISGNLDSPEGGFDAIMQVAVCGEHIGWRNVTR-LLVFSTDAGFHFAGDGKLGGIVLPNDGRCHLEN-DMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVINLIVDAYNSLSSEVILENSKLPEGVTITYQSRCKNGVVNEGES---GRKCSNISIGDEVSFNINITAQGCPK--QGKTETIKIKPLGFTEEVEITLSFICECECH---KHAMKNSPLCHNGNGSFECGACRCNKGRVGRQCECRKDEVSTE-DLDKNCRKD-NGTDICSNNGECVCGTCECKKRENPEERYSGKYCECDNFNCDRSNNKLCGG--HGRCECRVCVCDANYTGSACDCSLDTSTCLASNK-QICNGRGICECGTCRCTDP---KFQGPTCEICPTCPGVCTE-HKECVQCRAFGTGEKK--DTCKRDCSYFNLIEVEDRDKLPQPVQAFPLMHCKERDARDCWFYYTYA-VNNNTEKEVHVVKTMECPPGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTTENPIYKS--PINKFQ--------NPNYGRKAAAL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11584-1", "uniprot_id": "ITBX_DROME", "id": "P11584-1", "name": "Integrin beta-PS", "aln": "------MILERNRRCQLALLM----------IAILAA----------------IAGQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDFKGQSRCYQNTSSLCPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIP-KKLEHPC------ENCKAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGD-VKITYFSSCLS--NGPEVQ---TSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQE-LKDCVQCQMYKTGELKNGDDCARNCTQFVPVGVEKVEIDETKDE----QMCKFFDEDDCKFMFKYS-EQG--ELHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQ--ATSTFK--------NPMYAGK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R2H2-1", "uniprot_id": "ITB3_RAT", "id": "Q8R2H2-1", "name": "Integrin beta-3", "aln": "--------MRTR-RPGQLWAT----------LLALGALAG--------------VVVGESNICTTRGVNS-------CQQCLAVSPVCAWCSDESLPQN-------SPRCNLKKNLL-----------------------------KDKCSPESIEFPVSEAQILEALPLS----SKGSG-DSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMFISPPQAIKNPC--YTMKSTCLPMFGYKHVLTLTDQVTRFNDEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGRCHIGPDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGL-----KSCVGLKIGDTVSFSIEAKVRGCP---QQKEQSFTIKPVGFKDSLTVQVTFDCDCDCQ---AFAQPLSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPS--QQEECSPK-EGQPICSQRGECLCGQCVCHSSDFG--KITGKYCECDDFSCVRYKGEMCSG--HGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNG-LLCSGRGNCECGSCVCVQP---GSYGDTCEKCPTCPDACSF-KKDCVECKKFNRGKLHEENNCNRFCRDDIEL-VKELTDTGKNAVN-----CTYKNEDDCVVRFQYY-EDSSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKE--ATSTFT--------NITYRGT--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54890-1", "uniprot_id": "ITB3_MOUSE", "id": "O54890-1", "name": "Integrin beta-3", "aln": "--------MRAQ-WPGQLWAA----------LLALGALAG--------------VVVGESNICTTRGVNS-------CQQCLAVSPVCAWCSDETLSQG-------SPRCNLKENLL-----------------------------KDNCAPESIEFPVSEAQILEARPLS----SKGSG-SSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMYISPPQAIKNPC--YNMKNACLPMFGYKHVLTLTDQVSRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGHCHIGTDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGL-----KSCVGLKIGDTVSFSIEAKVRGCP---QEKEQSFTIKPVGFKDSLTVQVTFDCDCACQ---AFAQPSSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPS--QQEECSPK-EGQPICSQRGECLCGQCVCHSSDFG--KITGKYCECDDFSCVRYKGEMCSG--HGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNG-LLCSGRGNCECGSCVCVQP---GSYGDTCEKCPTCPDACSF-KKECVECKKFNRGTLHEENTCSRYCRDDIEQ-VKELTDTGKNAVN-----CTYKNEDDCVVRFQYY-EDTSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKE--ATSTFT--------NITYRGT--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05106-1", "uniprot_id": "ITB3_HUMAN", "id": "P05106-1", "name": "Integrin beta-3", "aln": "--------MRARPRPRPLWAT----------VLALGALAG--------------VGVGGPNICTTRGVSS-------CQQCLAVSPMCAWCSDEALPLG-------SPRCDLKENLL-----------------------------KDNCAPESIEFPVSEARVLEDRPLS----DKGSG-DSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPC--YDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGL-----KSCMGLKIGDTVSFSIEAKVRGCP---QEKEKSFTIKPVGFKDSLIVQVTFDCDCACQ---AQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPS--QQDECSPR-EGQPVCSQRGECLCGQCVCHSSDFG--KITGKYCECDDFSCVRYKGEMCSG--HGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNG-LLCSGRGKCECGSCVCIQP---GSYGDTCEKCPTCPDACTF-KKECVECKKFDRGALHDENTCNRYCRDEIES-VKELKDTGKDAVN-----CTYKNEDDCVVRFQYY-EDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKE--ATSTFT--------NITYRGT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18084-1", "uniprot_id": "ITB5_HUMAN", "id": "P18084-1", "name": "Integrin beta-5", "aln": "--------MPRAPAPLYAC------------LLGLCA---------------LLPRLAGLNICTSGSATS-------CEECLLIHPKCAWCSKEDFGSPR----SITSRCDLRANLV-----------------------------KNGCGG-EIESPASSFHVLRSLPLS----SKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAP-RYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQ-----RKCEGLKIGDTASFEVSLEARSCPS--RHTEHVFALRPVGFRDSLEVGVTYNCTCGCS---VGLEPNSARCN-GSGTYVCGLCECSPGYLGTRCECQDGENQSV--YQNLCREA-EGKPLCSGRGDCSCNQCSCFESEFG--KIYGPFCECDNFSCARNKGVLCSG--HGECHCGECKCHAGYIGDNCNCSTDISTCRGRDG-QICSERGHCLCGQCQCTEP---GAFGEMCEKCPTCPDACST-KRDCVECLLLHSG-KPDNQTCHSLCRDEVITWVDTIVKDDQEAVL-----CFYKTAKDCVMMFTYV-ELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRK--PISTHTVDFTFNKFNKSYNGTVD------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70309-1", "uniprot_id": "ITB5_MOUSE", "id": "O70309-1", "name": "Integrin beta-5", "aln": "--------MPRVPATLYAC------------LLGLCA---------------LVPRLAGLNICTSGSATS-------CEECLLIHPKCAWCSKEYFGNPR----SITSRCDLKANLI-----------------------------RNGCEG-EIESPASSTHVLRNLPLS----SKGSSATGSDVIQMTPQEIAVSLRPGEQTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAP-RYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILHGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGISYPGQ-----RKCEGLKIGDTASFEVSVEARSCPG--RQAAQSFTLRPVGFRDSLQVEVAYNCTCGCS---TGLEPNSARCS-GNGTYTCGLCECDPGYLGTRCECQEGENQSG--YQNLCREA-EGKPLCSGRGECSCNQCSCFESEFG--RIYGPFCECDSFSCARNKGVLCSG--HGECHCGECKCHAGYIGDNCNCSTDVSTCKAKDG-QICSDRGRCVCGQCQCTEP---GAFGETCEKCPTCPDACSS-KRDCVECLLLHQG-KPDNQTCHHQCKDEVITWVDTIVKDDQEAVL-----CFYKTAKDCVMMFSYT-ELPNGRSNLTVLREPECGSAPNAMTILLAVVGSILLIGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRK--PISTHTVDFAFNKFNKSYNGSV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1MSX8-1", "uniprot_id": "Q1MSX8_DANRE", "id": "Q1MSX8-1", "name": "Integrin beta", "aln": "MCRCDLGRMDKEKTSVTRCGR----------MWKLCSSTRHPALLVCIVLEIFIHSVKGLNVCMSGSATS-------CEECLLIHPSCAWCAQEDFGQAR----TLTSRCDFSQNLQ-----------------------------KRGCDAPFIENPRSGSSVLQSKPLS----YKGSGVTQYDVIQIYPQKISLSLRPGDQASFEVQVRPVEDYPVDLYYLMDLSLSMKDDLDTIRNLGTKLAEEMRKLTSNFRLGFGSFVDKNISPFSYTAS-KYQDNPCNGYKLFPNCVPTFGFRHLLSLTDKVDRFNEEVQKQMVSRNRDAPEGGFDAILQAAVCREKIGWRKEAYHLLVFATDDVPHLALDGKLGGLVHPHDGQCHLNDKNEYSASTKMDYPSLALLGEKLAENNIFLIFAVIKRHYVLYKNLTALIPGTTVEILDQDSKNIIQLIVNAYNNIRSKVELSVWDHPEDLSLAFSATCQDGQPLTGL-----RKCADLKIGDTVSFNVTVDARGCPP--KGTRKSFTIRPVGFKDRLEVSVDYRCDCRCT---YHTKPNSSRCN-SAGTYNCGLCRCEPGYLGARCECQEGEVDHQ--HLSACREA-EGKQVCSGRGECSCNQCLCYESEFG--KIYGTFCECDDFSCARHKGILCSG--HGECHCGECKCHAGYIGDNCNCSTETASCVSDDG-KICSGRGSCVCGRCQCTEP---GAFGDTCEKCPTCPDACGT-KRECIECRLFNTGRLADNQTCQRMCKDEITT-VETLKTDDPNAVQ-----CVYKTENDCVMKFTYS-EHANGQSVLTALKEPECAVAPNAMTVLLAVVGSILLMGIVLLALWKLVITVHDRREFARFQSARSRARYEMASNPVYKR--SVPMET-DFDMHGI-KSLNGGVH------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AYF4-1", "uniprot_id": "ITB6_RAT", "id": "Q6AYF4-1", "name": "Integrin beta-6", "aln": "------------MGIELVCLF----------LLLLGR----------------NDHVQGG--CAWSGAET-------CSDCLLTGPHCAWCSQENFTHLS----GAGERCDTPENLL-----------------------------AKGCQLPFIENPVSQVEILQNKPL-----SVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTP-EEITNPCS--SIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQ-----KKCSHMKVGDTASFNVSVSITNCE----KRSRKLIIKPVGLGDTLEILVSAECDCDCQ---REVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVS-----TDSCKES-PGHPSCSGRGDCYCGQCVCHLSPYG--SIYGPYCQCDNFSCLRHKGLLCGD--NGDCDCGECVCRDGWTGEYCNCTTSRDACASEDG-VLCSGRGDCVCGKCVCRNP---GASGPTCERCPTCGDPCNS-RRSCIECYLSADGQAQEE--CEDKCKATGATISEE-EFSKDTSVP-----CSLQGENECLITFLIT-ADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRG--STSTFKNVTYKHREKHKVGLSSDG-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0T9-1", "uniprot_id": "ITB6_MOUSE", "id": "Q9Z0T9-1", "name": "Integrin beta-6", "aln": "------------MGIELVCLF----------LLLLGR----------------NDHVQGG--CAWGGAES-------CSDCLLTGPHCAWCSQENFTHLS----GAGERCDTPANLL-----------------------------AKGCQLPFIENPVSRIEVLQNKPL-----SVGRQKNSSDIVQIAPQSLVLKLRPGREQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTP-EEITNPCS--SIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDHRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCNNGVLFPHQ-----KKCSHMKVGDTASFNVTVSVSNCE----KRSRNLIIKPVGLGDTLEILVSAECDCDCQ---REIETNSSKCHNGNGSFQCGVCTCNPGHMGPHCECGEDMVS-----TDSCKES-PGHPSCSGRGDCYCGQCICHLSPYG--SIYGPYCQCDNFSCLRHKGLLCGD--NGDCDCGECVCRDGWTGEYCNCTTNRDSCTSEDG-VLCSGRGDCVCGKCVCRNP---GASGPTCERCPTCGDPCNS-KRSCIECYLSADGQAQEE--CADKCKAIGATISEE-DFSKDTSVS-----CSLQGENECLITFLIT-TDNEGKTIIHNINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRG--STSTFKNVTYKHREKHKAGLSSDG-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18564-1", "uniprot_id": "ITB6_HUMAN", "id": "P18564-1", "name": "Integrin beta-6", "aln": "------------MGIELLCLF----------FLFLGR----------------NDHVQGG--CALGGAET-------CEDCLLIGPQCAWCAQENFTHPS----GVGERCDTPANLL-----------------------------AKGCQLNFIENPVSQVEILKNKPL-----SVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTP-EEIANPCS--SIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTAICNNGTLFQHQ-----KKCSHMKVGDTASFSVTVNIPHCE----RRSRHIIIKPVGLGDALELLVSPECNCDCQ---KEVEVNSSKCHHGNGSFQCGVCACHPGHMGPRCECGEDMLS-----TDSCKEA-PDHPSCSGRGDCYCGQCICHLSPYG--NIYGPYCQCDNFSCVRHKGLLCGG--NGDCDCGECVCRSGWTGEYCNCTTSTDSCVSEDG-VLCSGRGDCVCGKCVCTNP---GASGPTCERCPTCGDPCNS-KRSCIECHLSAAGQAREE--CVDKCKLAGATISEEEDFSKDGSVS-----CSLQGENECLITFLIT-TDNEGKTIIHSINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRG--STSTFKNVTYKHREKQKVDLSTDC-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGX0-1", "uniprot_id": "F1QGX0_DANRE", "id": "F1QGX0-1", "name": "Integrin beta", "aln": "------------MGIVSLCLV----------LYFW------------------LDSVGGT--CSQISALS-------CDDCLQLGPQCAWCTLQNFTDFF----PVDERCDTPEALL-----------------------------QKGCSGEFVEFPVTNVKVLKDQ-------GLGKNSGHTNVSYIAPQKMRLQLRPGSQLTFQIQVQQPKDHPVDIYYLMDLSASMFDDLKKIKDLGSTLSKEMANLTSKFRLGFGSFVEKPVLPFIKITR-EELANPCR--SFDLECLPTFGYRHLLSLTSSTDRFNEIISKQQISANIDIPEGGFDAIMQAAVCGDRIGWRNDSMKLLVFVSDADSHFGMDSKMSGIVVPNDGECHLDGNNEYSMTAHLEYPTLGQLVDKLVENNILLIFAVTKDQKENYENYASLIPGATVGVLASDSRNILELIMTSYKELRSEIDLEVLGNTEGLQMSFTALCQDGTITPGH-----KNCTNVKAGDVVSFNVTVEIKGCL----GGPRRFSLRPVGFQDALEIELESQCVCSCH---QTPETNSSFCSRGRGALECGECVCDPGFVGPKCECTESQDQ-----VSDCRAN-EGAEVCSGQGECFCGQCVCLPSSFG--RVYGPYCECDNFSCLRFRGELCGG--HGECDCGECVCDSGWMGEFCNCSTSNRSCVSSDG-SVCSGRGRCVCGKCECSVP---GASGKHCERCPTCGDICSI-HRSCAECFLKAK-EPSDE--CAVKCSSLHTAVSNSTDFEESRAAP-----CTLQSEESCLLSFSLV-ASDHG-SIIYNPKLYDCSEPPNAPLIALGVCMSVLIIGIALLVIWKFLVSVHDRKEVAKFEAEKAKAKWQSGTNPLFRS--STSTFKNVTYKSTGQQKSDVSLGR-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V7M2-1", "uniprot_id": "G3V7M2_RAT", "id": "G3V7M2-1", "name": "Integrin beta", "aln": "-------MVDSSTVLIFLLVLGGGQSELDTKITSSGETTE-------------WEDPDLSPQGSCQPAPS-------CQKCILSHPSCAWCKQLNFTASG---EAEARRCARREELL-----------------------------ARGCPEQELEEPRGHQEVLQDRP-------LSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGQALLLRLREVTHSVRIGFGSFVDKTVLPFVSTVP-SKLNHPCP--SRLERCQAPFSYHHVLPLTRDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSR-LLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELSQLIPKSAVGELSEDSSNVVQLIMDAYDNLSSTVTLEHSSLPPGVSISFESHCRSPEKSEGEAGDRRGQCNHVRVNQMVDFWVTLQASHCLPEA----HVLRLWALGFSEELTVELHTLCDCNCS----DAQPRAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSP-DLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSS------GRLCECDDASCERHEGILCGG--FGHCQCGVCHCHANRTGRACECSESVDSCVSPEG-GLCSGHGDCKCNRCQCLDG----YYGALCDQCLGCKSPCEQ-YRDCAECGAFGTGPLAAN--CSAACADVNVTLALAPNLDD--------GWCKERTLDN-QLFFFLVENSARG-VILRVRPQEKGAD--HTRAIILGCVGGIVAVGLGLVLAYRLSVEVYDRLEYSRFEKERQQLNWKQDSNPLYKS--AVTTTV--------NPRFQGGNKQSLSLPLTQEAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26011-1", "uniprot_id": "ITB7_MOUSE", "id": "P26011-1", "name": "Integrin beta-7", "aln": "-------MVDSSTVLIFLLVLGGGQSELDTKITSSGEAAE-------------WEDPDLSLQGSCQPVPS-------CQKCILSHPSCAWCKQLNFTASG---EAEARRCARREELL-----------------------------ARGCPAQELEEPRGRQEVLQDKP-------LSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVP-SKLHHPCP--SRLERCQPPFSFHHVLSLTGDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSR-LLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELRQLIPKSAVGELSEDSSNVVQLIMDAYDSLSSTVTLEHSPLPPGVSISFESHCKGPEKTEGEAGDR-GQCNDVRVNQTVDFWVTLQATHCLPEA----HVLRLWALGFSEELTVELHTVCDCNCG----DAQPHAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSP-DLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSS------GRLCECDDASCERHEGILCGG--FGHCQCGVCHCHANHTGRACECSKSVDSCVSPEG-GLCSGHGYCKCNRCQCLDG----YYGALCDQCLGCKSPCEQ-YRDCAECGAFGTGPLAAN--CSVVCADVNVTLTLAPNLDD--------GWCKERTIDN-QLFFFLVEHAASG-IVLRVRPQEKGVD--HTRAIILGCTGGIVAVGLGLVLAYRLSVEIYDRREYRRFEKEQQQLNWKQDNNPLYKS--AITTTV--------NPRFQGTNGRSPSLSLTREAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26010-1", "uniprot_id": "ITB7_HUMAN", "id": "P26010-1", "name": "Integrin beta-7", "aln": "-------MVALPMVLVLLLVLSRGESELDAKIPSTGDATE-------------WRNPHLSMLGSCQPAPS-------CQKCILSHPSCAWCKQLNFTASG---EAEARRCARREELL-----------------------------ARGCPLEELEEPRGQQEVLQDQP-------LSQGARGEGATQLAPQRVRVTLRPGEPQQLQVRFLRAEGYPVDLYYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVP-SKLRHPCP--TRLERCQSPFSFHHVLSLTGDAQAFEREVGRQSVSGNLDSPEGGFDAILQAALCQEQIGWRNVSR-LLVFTSDDTFHTAGDGKLGGIFMPSDGHCHLDSNGLYSRSTEFDYPSVGQVAQALSAANIQPIFAVTSAALPVYQELSKLIPKSAVGELSEDSSNVVQLIMDAYNSLSSTVTLEHSSLPPGVHISYESQCEGPEKREGKAEDR-GQCNHVRINQTVTFWVSLQATHCLPEP----HLLRLRALGFSEELIVELHTLCDCNCS----DTQPQAPHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSP-DLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSS------GHLCECDDASCERHEGILCGG--FGRCQCGVCHCHANRTGRACECSGDMDSCISPEG-GLCSGHGRCKCNRCQCLDG----YYGALCDQCPGCKTPCER-HRDCAECGAFRTGPLATN--CSTACAHTNVTLALAPILDD--------GWCKERTLDN-QLFFFLVEDDARGTVVLRVRPQEKGAD--HTQAIVLGCVGGIVAVGLGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKS--AITTTI--------NPRFQEADSPTL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RYB8-1", "uniprot_id": "B2RYB8_RAT", "id": "B2RYB8-1", "name": "Integrin beta", "aln": "-------MLGP-HTLLLILAG----------LLFLG--------------------SALSEECTKYKVSN-------CRDCIQSGPGCSWCQKLNFTGPG---EPDSLRCDTRAQLL-----------------------------LKGCPADDIMDPKSFADLHPQYQ-------VQR-------SQLSPQKVTLNLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFVNTHP-EKLRNPCP--NKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAIMQVAACPEEIGWRNVTR-LLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDN-MYKRSNEFDYPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKKAYYKLSSRVFLDHTTIPDTLKVTYDSFCNNRVSSIG---KSRGDCDGVQINNPVTFQVKVTASECIQE-----QSFVIRALGFTDTVTVQVHPQCECQCR----DQSRMRNLCG-GKGVMECGICRCESGYIGKNCECQTQGRSSQ-ELEGNCRKDNSS-IVCSGLGDCICGQCVCHTSDIPNKVIFGQYCECDNFNCERYDGQVCGGLKRGSCSCGQCNCKEGFEGSACQCQRSTTGCLNARL-VECSGRGRCQCNRCICEKG----YQPPLCEECPGCPLPCST-YVFCAECLKFDKGPFQKN--CSVQCANV--TLQTVPFKKK--------PCK-ERDSEGCWITYTLQQKDG-NAYNIHVDDDRECVKGPNVAAIIGGTVAGVVLIGVLLLVIWKALTHLTDLNEYRRFEKEKLKSQWNND-NPLFKS--ATTTVM--------NPKFAES--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11835-1", "uniprot_id": "ITB2_MOUSE", "id": "P11835-1", "name": "Integrin beta-2", "aln": "-------MLGLRPSLLLALAG----------LFFLG--------------------SAVSQECTKYKVSS-------CRDCIQSGPGCSWCQKLNFTGPG---EPDSLRCDTRAQLL-----------------------------LKGCPADDIMDPRSIANPEFDQR-------GQR-------KQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFVNTHP-EKLRNPCP--NKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAIMQVAACPEEIGWRNVTR-LLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDN-MYKRSNEFDYPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKNAYYKLSSRVFLDHSTLPDTLKVTYDSFCSNGASSIG---KSRGDCDGVQINNPVTFQVKVMASECIQE-----QSFVIRALGFTDTVTVQVRPQCECQCR----DQSREQSLCG-GKGVMECGICRCESGYIGKNCECQTQGRSSQ-ELERNCRKDNSS-IVCSGLGDCICGQCVCHTSDVPNKEIFGQYCECDNVNCERYNSQVCGGSDRGSCNCGKCSCKPGYEGSACQCQRSTTGCLNARL-VECSGRGHCQCNRCICDEG----YQPPMCEDCPSCGSHCRDNHTSCAECLKFDKGPFEKN--CSVQCAGM--TLQTIPLKKK--------PCK-ERDSEGCWITYTLQQKDGRNIYNIHVEDSLECVKGPNVAAIVGGTVVGVVLIGVLLLVIWKALTHLTDLREYRRFEKEKLKSQWNND-NPLFKS--ATTTVM--------NPKFAES--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05107-1", "uniprot_id": "ITB2_HUMAN", "id": "P05107-1", "name": "Integrin beta-2", "aln": "-------MLGL-RPPLLALVG----------LLSLG--------------------CVLSQECTKFKVSS-------CRECIESGPGCTWCQKLNFTGPG---DPDSIRCDTRPQLL-----------------------------MRGCAADDIMDPTSLAETQEDHN-------GGQ-------KQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNTHP-DKLRNPCP--NKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTR-LLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDN-LYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRN---QPRGDCDGVQINVPITFQVKVTATECIQE-----QSFVIRALGFTDIVTVQVLPQCECRCR----DQSRDRSLCH-GKGFLECGICRCDTGYIGKNCECQTQGRSSQ-ELEGSCRKDNNS-IICSGLGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERTTEGCLNPRR-VECSGRGRCRCNVCECHSG----YQLPLCQECPGCPSPCGK-YISCAECLKFEKGPFGKN--CSAACPGL--QLSNNPVKGR--------TCK-ERDSEGCWVAYTLEQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNND-NPLFKS--ATTTVM--------NPKFAES--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UV74-1", "uniprot_id": "ITB2L_MOUSE", "id": "Q3UV74-1", "name": "Integrin beta-2-like protein", "aln": "-------MLGQ-CTLLPVLAG----------LLSLE--------------------SALSQLCTKDNVST-------CQDCIRSGPSCAWCQKLNFTGRG---EPDSVRCDTPEQLL-----------------------------LKGCTSEYLVDPKSLAESQEDKE-------RDQ-------RQLSPRNVTVFLRPGQAATFKVDFQRTQDNSVDLYFLMGLSGSAQGHLSNVQTLGSDLLKALNEISRSGRIGFGSIVN-------------------------------MTFQHILKLTADSSQFQRELRKQLVSGKLATPKGQLDAVVQVAICLGEIGWRNGTR-FLVLVTDNDFHLAKDKTLGTRQNTSDGRCHLDDG-MYRSRGEPDYQSVVQLASKLAENNIQPIFVVPSRMVKTYEKLTTFIPKLTIGELSDDSSNVAQLIRNAYSKLSSIVVLNHSTIPSILKVTYDSYCSNGTSNPG---KPSGDCSGVQINDQVTFQVNITASECFRE-----QFFFIQALGFMDSVTVRVLPLCECQCQ----EQSQHHSLCG-GKGAMECGICRCNSGYAGKNCECQTQGPSSQ-DLEGSCRKDNSS-IMCSGLGDCICGQCECHTSDIPNKEIYGQYCECNNVNCERYDGQVCGGPERGHCSCGRCFCRYGFVGSACQCRMSTSGCLNNRM-VECSGHGRCYCNRCLCDPG----YQPPLCEKRPGYFHRCSE-YYSCARCLKDNSAIKCR------ECWNL--LFSNTPFSNK--------TCMTERDSEGCWTTYTLYQPDQSDINSIYIKESLVCAEISNTTILLG-VIVGVLLAVIFLLVY--CMVYLKGTQKAAKLPRKGGAQSTLAQ-QPHFQEPHHVEPVW--------NQERQGTQ-------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * *: * ** : * . . : *: : : ** . : : . .:*:*:**.** * .. : ** * : .:: . ::***::*: ::: : *. *. : . :* : *:* :**::*. * ****: : :**: :* * . * :. . ** **: * :* :: : : : **.* *:: * : * :* *: .*: * .: : : :. : : : : * . .* : . * * : : .:*: : : : : * * * . . * ** * * . * *** * ** * * *. * * * *:*: .* * . :*.. * * * * * . * * * * *. :* * *. * * *: * * .* * : : : .:: : : . . : :: :* :: ", "identical_positions": 109, "similar_positions": 128, "identity": "11.8%" }, { "cls_id": "homologset.agr.FB:FBgn0004666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AA36-1", "uniprot_id": "D4AA36_RAT", "id": "D4AA36-1", "name": "", "aln": "------------------------MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRTGPLDSVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHPPLHHHLLQEY-------------------------EIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHNNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDTFHLRYAHHLLLVKGQVTTKYYRLLSKLGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEVEYKELQLSLDQVSTSKSQESWR-TTLSTSQETRKSAKPKTTKMRTKLRTNPYPSQQYSSFQMDKLECSQAGNWRTSPPTSAVAPPEQQLH----SEASDLLYGPPYSLPFSYRYGHFPLDSHVFSSKKPGLPAKFGQPQGSPCEVARFFLSTLPASSECQWH---YANSLMPSSPSPAKNLSE-SPVNAARHGLVPNYEAPAATARRFGEDPAPSSFPSCGHYREEPTLGS----------AKAARQASR-DTARLALARATPEC------------------CAPPAPE------------------------------------PQAPAQLPFVLLN---YHRVLARRGPLG---------SAAPGAPEAA-GSLRPRHPGPVAASAPG-----------------------------------APRPHYLGASVIITNGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61079-1", "uniprot_id": "SIM2_MOUSE", "id": "Q61079-1", "name": "Single-minded homolog 2", "aln": "------------------------MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRTGPLDSVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHPPLHHHLLQEY-------------------------EIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDTFHLRYAHHLLLVKGQVTTKYYRLLSKLGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTDVEYKELQLSLDQVSTSKSQESWR-TTLSTSQETRKSAKPKNTKMKTKLRTNPYPPQQYSSFQMDKLECSQVGNWRTSPPTNAVAPPEQQLH----SEASDLLYGPPYSLPFSYHYGHFPLDSHVFSSKKPGLPAKFGQPQGSPCEVARFFLSTLPASSECQWH---CANSLVPSSSSPAKNLSEPSPVNAARHGLVPNYEAPSAAARRFCEDPAPPSFPSCGHYREEPALGP----------AKAPRQASR-DAARLALARAPPEC------------------CAPPAPE------------------------------------PQAPAQLPFVLLN---YHRVLARRGPLG---------SAAPGAPEAA-GSLRPRHPGPVAASAPG-----------------------------------APRPHYLGASVIITNGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14190-1", "uniprot_id": "SIM2_HUMAN", "id": "Q14190-1", "name": "Single-minded homolog 2", "aln": "------------------------MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRAGPLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHHHLLQEY-------------------------EIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLYSNMFMFRASLDLKLIFLDSRVTEVTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKRGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEIEYKELQLSLEQVSTAKSQDSWR-TALSTSQETRKLVKPKNTKMKTKLRTNPYPPQQYSSFQMDKLECGQLGNWRASPPASAAAPPELQPH----SESSDLLYTPSYSLPFSYHYGHFPLDSHVFSSKKPMLPAKFGQPQGSPCEVARFFLSTLPASGECQWH---YANPLVPSSSSPAKNPPE-PPANTARHSLVPSYEAPAAAVRRFGEDTAPPSFPSCGHYREEPALGP----------AKAARQAAR-DGARLALARAAPEC------------------CAPPTPEA-----------------------------------PGAPAQLPFVLLN---YHRVLARRGPLGGAAPAASGLACAPGGPEAATGALRLRHPSPAATSPPG-----------------------------------APLPHYLGASVIITNGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZMU8-1", "uniprot_id": "D3ZMU8_RAT", "id": "D3ZMU8-1", "name": "", "aln": "------------------------MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHTSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEY-------------------------EIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISPSKPTFSYTSSSTPTITDNRKGAKSRLSSSKSKSRTSPYP--QYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPE-RPGSQHELSCAYRQFPDRGSLCYG-FALDHSRLVEDR---HFHTQACEGGRCEAGRYFLGAPPAGRDPWWG-SRAALPLTKASPESRETYENSMPHITSVHRLHGRGHWDEDSVVS-SPDPGSASE-SGDRYRSEQYQNSPHEPSKIETLIRATQQMIKEEENRLQLRKAPPDQ-LASINGAGKKHSLCFANYQQPPPAGEVCHSSALTSTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPSSDRITKSSLILAKDYLHSDMSPHQTAGDHPAISPNCFGSHRQYFDKH-AYTLTGYALEHLYDSETIRNYSLGCNG-SHFDVTSHLRMQPDPAQGHKGTSVIITNGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61045-1", "uniprot_id": "SIM1_MOUSE", "id": "Q61045-1", "name": "Single-minded homolog 1", "aln": "------------------------MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHTSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEY-------------------------EIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPTFSYTSSSTPTISDNRKGAKSRLSSSKSKSRTSPYP--QYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPE-RPGSQHELSCAYRQFPDRSSLCYG-FALDHSRLVEDR---HFHTQACEGGRCEAGRYFLGAPPTGRDPWWG-SRAALPLTKASPESREAYENSMPHITSIHRIHGRGHWDEDSVVS-SPDPGSASE-SGDRYRTEQYQNSPHEPSKIETLIRATQQMIKEEENRLQLRKAPPDQ-LASINGAGKKHSLCFANYQQPPPTGEVCHSSALASTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPSSDRITKSSLILAKDYLHSDMSPHQTAGDHPAISPNCFGSHRQYFDKH-AYTLTGYALEHLYDSETIRNYSLGCNG-SHFDVTSHLRMQPDPAQGHKGTSVIITNGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81133-1", "uniprot_id": "SIM1_HUMAN", "id": "P81133-1", "name": "Single-minded homolog 1", "aln": "------------------------MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHSSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEY-------------------------EIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYP--QYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPADRPGSQHDASCAYRQFSDRSSLCYG-FALDHSRLVEER---HFHTQACEGGRCEAGRYFLGTPQAGREPWWG-SRAALPLTKASPESREAYENSMPHIASVHRIHGRGHWDEDSVVS-SPDPGSASE-SGDRYRTEQYQSSPHEPSKIETLIRATQQMIKEEENRLQLRKAPSDQ-LASINGAGKKHSLCFANYQQPPPTGEVCHGSALANTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPNSDRISKSSLILAKDYLHSDISPHQTAGDHPTVSPNCFGSHRQYFDKH-AYTLTGYALEHLYDSETIRNYSLGCNG-SHFDVTSHLRMQPDPAQGHKGTSVIITNGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SJ5-1", "uniprot_id": "SIM1A_DANRE", "id": "Q98SJ5-1", "name": "Single-minded homolog 1-A", "aln": "------------------------MKEKSKNAGRTRREKENSEFYELAKLLPLPSAITSQSDKASIIRLTTSYLKMRIVFPEGLGESWGHVSRTTSLENVGRELGSHLLQTLDGFIFVVAPDGKILYISETASVHLGLSQEELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVHEY-------------------------EMERSFFLRMKCVLAKANAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHSCDTFHLRCAHHLLLVKGQVTTKYYRFLAKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQAASTKPSFTYNSPSNP-VTENRRVGKSRVSRTKTKTRLSPYS--QYPGFPTDRSESDQDSPWGGSPLTDSASPQLLEQC----EGIESSCVYRQFSDPRSLCYG-LPLTEDHHTSNELYSHPHSESCERGCCKAGRYFLGTPQPGREAWWGAARSVLPLPKSSPENGDSFEGVSPHIASIHSLQVRGHWDEDSAVSSAPDGGSASD-SGDRFRADQCRSSPQEPSKIETLIRATQQMIKEEESRLQLRKLPTDVPLEPTNSLAK--SFHSTDFPQSAMQSVVCRG---------------PAQVISPAP-----SPVPLSRLSSPLPDRLSKGKDFLQNELSSSQLPLTGTCAVSPTPALYSLHP-RQYLEKHAAYSLTSYALEHLYEADTFRGYSLGCSGSSHYDMTTHLRK-AEQAPGHKGTSVIITNGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05709-1", "uniprot_id": "SIM_DROME", "id": "P05709-1", "name": "Protein single-minded", "aln": "MTNHRRVRKDCYESRLHDIAKTCAMKEKSKNAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGLGEAWG-SSPAMQRGATIKELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIFEYIHNYDQDEMNAILSLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKTFFLRMKCVLAKRNAGLTTSGFKVIHCSGYLKARIYPDRGDGQGSLIQNLGLVAVGHSLPSSAITEIKLHQNMFMFRAKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYKGQVTTKYYRFLTKGGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLVLNEIQTGVVKREPISPAAQAAQAAQAAQAAQAAQAAQAAHVAQAVQA--QVVVVPQQSVVVQPQCAGATGQPVGPGTPVSLALS---ASPKLDPYFEPELPLQPAVTPVPPTNNSSSSSNNNNGVWHHHHVQQQQQSGS----MDHDSLSYTQLYP---PLNDLVVSSSSSVGGGTASSAGGGSSASASSSGVYSTEMQYP-DTTTGNLYYNNNNHYYYDYDAT-----------VDVATSMIRPFSANSNSCSSSSES-------------------ERQLSTG-----------------------------------NASIVNETSPSQTTYSDLSHNFELSYFS---------DNSSQQHQHQQQQQHLMEQQHLQYQYATW---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********.:******* ** *********:***** ****:*********** ***:***::** * : . :*************:****.****:************** *******:**** *:***.*:*: * : * : : *:*::*********** ***** .*:********** * * . .. * :******:***.**:*****:.*******.**:****:*:**:::**************:::*..* : :* :*::** **********:*:* ***********:******** ********:: * * * *. * . * . . : : :. : :: . * . : . ... :* . . : . ... : : . :. . : * :*.. . : . . .:: : .. . : . ..: . . . . : . ", "identical_positions": 242, "similar_positions": 115, "identity": "29.26%" }, { "cls_id": "homologset.agr.FB:FBgn0004687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17209-1", "uniprot_id": "MYL4_RAT", "id": "P17209-1", "name": "Myosin light chain 4", "aln": "--------------------------------------MPPKKPEPKKETAK--VAAAPAPAPAPAP--------EPLRDS--------AFDPKSVKIDFSADQIEEFKEAFSLFDRTPTGEMKITYGQC-GDVLRALGQNPTNAEVLRVLGKPK--PEEMNSKTLDFEMFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMSEAEVEQLLTGQE-DANGCINYEAFVKHVMSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09541-1", "uniprot_id": "MYL4_MOUSE", "id": "P09541-1", "name": "Myosin light chain 4", "aln": "--------------------------------------MPPKKPEPKKEAAK--PAAAPAPAASAAP--------EPLKDS--------AFDPKSVKIDFSADQIEEFKEAFSLFDRTPTGEMKITYGQC-GDVLRALGQNPTNAEVLRVLGKPK--PEEMSSKTLDFEMFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMSEAEVEQLLSGQE-DANGCINYEAFVKHIMSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12829-1", "uniprot_id": "MYL4_HUMAN", "id": "P12829-1", "name": "Myosin light chain 4", "aln": "--------------------------------------MAPKKPEPKKEAAK--PAPAPAPAPAPAP--------APAPEAP----KEPAFDPKSVKIDFTADQIEEFKEAFSLFDRTPTGEMKITYGQC-GDVLRALGQNPTNAEVLRVLGKPK--PEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQE-DANGCINYEAFVKHIMSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09542-1", "uniprot_id": "MYL3_MOUSE", "id": "P09542-1", "name": "Myosin light chain 3", "aln": "--------------------------------------MAPKKPEPKKDDAKA-AAPKAAPAPAAAPAAAPAAAPEPERPK------EAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQC-GDVLRALGQNPTQAEVLRVLGKPK--QEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16409-1", "uniprot_id": "MYL3_RAT", "id": "P16409-1", "name": "Myosin light chain 3", "aln": "--------------------------------------MAPKKPEPKKDDAKT-AAPKAAPAPAAAPAAAP----EPERPK------EAEFDASKIKIEFTPEQIEEFKEAFQLFDRTPKGEMKITYGQC-GDVLRALGQNPTQAEVLRVLGKPK--QEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08590-1", "uniprot_id": "MYL3_HUMAN", "id": "P08590-1", "name": "Myosin light chain 3", "aln": "--------------------------------------MAPKKPEPKKDDAK--AAPKAAPAPAPPP--------EPERPK------EVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQC-GDVLRALGQNPTQAEVLRVLGKPR--QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZM3-1", "uniprot_id": "A0A8N7UZM3_DANRE", "id": "A0A8N7UZM3-1", "name": "", "aln": "--------------------------------------MAPKKVEPKKPEPKK-PEAKKEEAPAPAP--------VPETPK------EPEVDLKSVPLDFSPDQIEEFRDAFTLFDETPTGEMKIRYAQC-GDVMRALGHNPTNADVLTVLGKPK--AEEMNTKYLDFETFLPMLQHISRAKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEDEVDRLMAGQE-DANGCINYTSFIKHILSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05977-1", "uniprot_id": "MYL1_MOUSE", "id": "P05977-1", "name": "Myosin light chain 1/3, skeletal muscle isoform", "aln": "--------------------------------------MAPKK-DVKKP------AAAPAPAPAPAP--------APAKPK------EEKIDLSAIKIEFSKEQQEDFKEAFLLFDRT--GECKITLSQV-GDVLRALGTNPTNAEVKKVLGNPS--NEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQE-DSNGCINYEAFVKHIMSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02600-1", "uniprot_id": "MYL1_RAT", "id": "P02600-1", "name": "Myosin light chain 1/3, skeletal muscle isoform", "aln": "--------------------------------------MAPKK-DVKKPA-----AAAPAPAPAPAP--------APAKPK------EEKIDLSAIKIEFSKEQQEEFKEAFLLFDRT--GECKITLSQV-GDVLRALGTNPTNAEVKKVLGNPS--NEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQE-DSNGCINYEAFVKHIMSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05976-1", "uniprot_id": "MYL1_HUMAN", "id": "P05976-1", "name": "Myosin light chain 1/3, skeletal muscle isoform", "aln": "--------------------------------------MAPKK-DVKKPVAAAAAAPAPAPAPAPAP--------APAKPK------EEKIDLSAIKIEFSKEQQDEFKEAFLLFDRT--GDSKITLSQV-GDVLRALGTNPTNAEVRKVLGNPS--NEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQE-DSNGCINYEAFVKHIMSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0G6-1", "uniprot_id": "MYL1_DANRE", "id": "Q6P0G6-1", "name": "Myosin, light chain 1, alkali; skeletal, fast", "aln": "--------------------------------------MAPKK-DAKKPEP----PKKAEPAPAPAP--------APEPPK------ADAVDLSGVKLDFTQDQMEDYREAFLLFDRV--GDSKVAYNQI-ADIMRALGQNPTNKEVTKILGNPT--ADDMVNKRVDFEGFLPMLQVVINNPNKATYDDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMSEAEIDALMQGQE-DENGCVNYEAFVKHIMSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CI43-1", "uniprot_id": "MYL6B_MOUSE", "id": "Q8CI43-1", "name": "Myosin light chain 6B", "aln": "--------------------------------------MPPKKDAPVKKPAGP-SISKPAAK-STPGTPLAKAKAEPAAPQAPAKSQEPPVDLSKVVIEFNKDQLEEFREAFELFDRV--GDGKILYSQC-GDLMRALGQNPTNAEVLKVLGNPK--NEELKSRRVDFETFLPMLQAVAKNRDQGTYEDYLEGLRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHE-DSNGCINYEAFLKHILSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RDP3-1", "uniprot_id": "M0RDP3_RAT", "id": "M0RDP3-1", "name": "", "aln": "MYVKNLCHGVPPPPSAPSLDPARDGCPCWHTVLLPPDIVPPKKDAPVKKPAGP-SISKRAAK-STAGTLLAKTKAEPAAPQTPTKTQEPPVDLSKVVIEFNKDQLEEFREAFELFDRV--GDGKLLYSQCWGDLIRTLGQNPTNAEVLKVLGNPK--NNELKSRRVDFETFLLMLQAVAKHRDQDTYEDYLDRLRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHE-DSNDCINYEVFLKHILSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14649-1", "uniprot_id": "MYL6B_HUMAN", "id": "P14649-1", "name": "Myosin light chain 6B", "aln": "--------------------------------------MPPKKDVPVKKPAGP-SISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFKEAFELFDRV--GDGKILYSQC-GDVMRALGQNPTNAEVLKVLGNPK--SDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHE-DSNGCINYEAFLKHILSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60605-1", "uniprot_id": "MYL6_MOUSE", "id": "Q60605-1", "name": "Myosin light polypeptide 6", "aln": "------------------------------------------------------------------------------------------------MCDFTEDQTAEFKEAFQLFDRT--GDGKILYSQC-GDVMRALGQNPTNAEVLKVLGNPK--SDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHE-DSNGCINYEAFVRHILSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60660-1", "uniprot_id": "MYL6_HUMAN", "id": "P60660-1", "name": "Myosin light polypeptide 6", "aln": "------------------------------------------------------------------------------------------------MCDFTEDQTAEFKEAFQLFDRT--GDGKILYSQC-GDVMRALGQNPTNAEVLKVLGNPK--SDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHE-DSNGCINYEAFVRHILSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64119-2", "uniprot_id": "MYL6_RAT", "id": "Q64119-2", "name": "Myosin light polypeptide 6", "aln": "------------------------------------------------------------------------------------------------MCDFTEDQTAEFKEAFQLFDRT--GDGKILYSQC-GDVMRALGQNPTNAEVLKVLGNPK--SDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHE-DSNGCINYEELLRMVLNG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6G5X1-1", "uniprot_id": "A0A8I6G5X1_RAT", "id": "A0A8I6G5X1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MCDFTEDQTTEFKEAFQLFDRT--GNGKILYSQC-GDVMRALGQNPTNTEVLKVLGNPK--SDEMNVEVLDFEHFLPMLQTVAKSKDQGTYEDYVEGLHVFDKEGNSAVLGAEIRHILVTLGENMTEEEVEMLVAGHE-DSNSCINYEELVRMVLNG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54357-1", "uniprot_id": "MLC2_DROME", "id": "P54357-1", "name": "Myosin-2 essential light chain", "aln": "------------------------------------------------------------------------------------------------MAAYTEDQLAEFQEAFNLFDNR--GDGKIQLSQV-GECLRALGQNPTESDVKKCTHQLK--PDER----ISFEVFLPIYQAISKARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANME-DQQGNINYEEFVRMVMSG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53141-1", "uniprot_id": "MLC1_YEAST", "id": "P53141-1", "name": "Myosin light chain 1", "aln": "-----------------------------------------------------------------------------------------------------MSATRANKDIFTLFDKK--GQGAIAKDSL-GDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVLRQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * ***. : : . .: :*::* ***: * : .: :: : : :*::. :: ***:... : .::* :* ***.:.: *:: :: . * * :. ::* ::. :: ", "identical_positions": 23, "similar_positions": 53, "identity": "9.09%" }, { "cls_id": "homologset.agr.FB:FBgn0004698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3D8-1", "uniprot_id": "D4A3D8_RAT", "id": "D4A3D8-1", "name": "p125", "aln": "--------MFQTLRPFHLSREQTLGNVGPPRTGRRTTLFLSLRALVVCMG-----AGFFGGRGPIRSWGCGQAWHASGRSRHAETFGSPAWLSGGTPLASMARKRTAGGK---RRKRGQEAED-------NKATRPEESDADDFEDEKQKPPRKCFLPKVSQGKRKRDCSDPGDPTNG-------------------------------------------AAKKKVAKATTKSKNLKAVKEEALSDDGDDFRDSLSNCRKAKKHPKREVVD------QGTDEDD--SEDDWEEVEELTEPVL--------------------DMGENSATSRSDLPVKAVEIEIETPEQAKARERSEKIKMEFETYLRRMMKRFNKEVQENMHKVHLLCLLASGFYRNSICQQPD-LLAIGLSIIPIRFTKVPLQDRDVYYLSNLVKWFIGTFTVN-----ADLSASEQDSLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVAK----------------------------------GKKSSKETSLEGPGDSSEPSSNIPESHNKPKTSKRIKQEETLSEGSG---------------------------------------------------------------------KANARGKRGTATAGSRQQRKPSCSE-----GEEAKQEIQSHPQAQ-----------------KRRVAAKVSYKEESESDGAGSGSDFELSSG----------------------------------EGQHSSDEDCKPGPRKQKRASAPQRSKAGSKSASKTQSGSQWEPPSFSVASSSS-------------------SACKRGKKISCGGEETD-----------------------------------------------------------------------DRKAAGVDQWLEVFCEPQAKWVCVDCVHGVVGQPVACYKYATKP---------MTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETLR------PYRSPLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPESAAVLGYCRG-------EAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDHNDLGLFGHWQTEEYQPPVAVD-GKVPRNEFGNVYLFLPSMMPIGCVQMNLPNLHRVARKLGIDCVQAITGFDFHGG-YCHPVTDGYVVCEEFRDVLLAAWENEQALIEKKEKEKKEKRALGNWKLLVRGLLIRERLKLRYGAKSEAAAPHANAGGGLSSDEEEGTSSQAEAAR--VLAASWPQNRETKEEQKPD-YTKMTRRRRAAEASHLFPFEKL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51612-1", "uniprot_id": "XPC_MOUSE", "id": "P51612-1", "name": "DNA repair protein complementing XP-C cells homolog", "aln": "----------------------------------------------------------------------------------------------------MAPKRTADGR---RRKRGQKTED-------NKVARHEESVADDFEDEKQKPRRKSSFPKVSQGKRKRGCSDPGDPTNG-------------------------------------------AAKKKVAKATAKSKNLKVLKEEALSD-GDDFRDSPADCKKAKKHPKSKVVD------QGTDEDD--SEDDWEEVEELTEPVL--------------------DMGENSATSPSDMPVKAVEIEIETPQQAKERERSEKIKMEFETYLRRMMKRFNKEVQENMHKVHLLCLLASGFYRNSICRQPD-LLAIGLSIIPIRFTKVPLQDRDAYYLSNLVKWFIGTFTVN-----ADLSASEQDDLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVTK----------------------------------GRKSSKETSVEGPGGSSELSSNSPESHNKPTTSRRIKEEETLSEGRG---------------------------------------------------------------------KATARGKRGTGTAGSRQRRKPSCSE-----GEEAEQKVQGRPHAR-----------------KRRVAAKVSYKEESESDGAGSGSDFEPSSG----------------------------------EGQHSSDEDCEPGPRKQKRASAPQRTKAGSKSASKTQRGSQCEPSSFPEASSSS-------------------SGCKRGKKVSSGAEEMA-----------------------------------------------------------------------DRKPAGVDQWLEVYCEPQAKWVCVDCVHGVVGQPVACYKYATKP---------MTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETLR------PYRSLLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPETAAVLGYCRG-------EAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDHNDLGLYGHWQTEEYQPPIAVD-GKVPRNEFGNVYLFLPSMMPVGCVQMTLPNLNRVARKLGIDCVQAITGFDFHGG-YCHPVTDGYIVCEEFRDVLLAAWENEQAIIEKKEKEKKEKRALGNWKLLVRGLLIRERLKLRYGAKSEAAAPHA-AGGGLSSDEEEGTSSQAEAAR--VLAASWPQNRED-PEQKSE-YTKMTRKRRAAEASHLFPFEKL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01831-1", "uniprot_id": "XPC_HUMAN", "id": "Q01831-1", "name": "DNA repair protein complementing XP-C cells", "aln": "----------------------------------------------------------------------------------------------------MARKRAAGGEPRGRELRSQKSKA-------KSKARREEEEEDAFEDEK--PPKKSLLSKVSQGKRKRGCSHPGGSADG-------------------------------------------PAKKKVAKVTVKSENLKVIKDEALSD-GDDLRDFPSDLKKAHHLKRGATMN------EDSNEEEEESENDWEEVEELSEPVLG-------------------DVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPD-LHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVN-----AELSASEQDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAK----------------------------------GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTC---------------------------------------------------------------------RPSAKGKRNKG--GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR-----------------ERRVASRVSYKEESGSDEAGSGSDFELSSG----------------------------------EASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSS-------------------SSSKRGKKMCSDGEKAE-----------------------------------------------------------------------KRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKP---------MTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETLR------PYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRG-------EAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVD-GKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGG-YSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAAR--ILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24595-1", "uniprot_id": "XPC_DROME", "id": "Q24595-1", "name": "DNA repair protein complementing XP-C cells homolog", "aln": "MSDEEEDSVSEGFSASEDEWKPSKDVKGGESSDDDDSDFDELQAEGGAAGSSGRSSAVAGKRGDHKAPSGIKGSSVKKRKPTGQSLRSKLYNKYRPPPKTFPTSPSQQKENTPRASGSKNAKTPNESGARNQHGPADSSSESSVEDYLVNPADLDLHSTFFAGGQKEKSPAPQFDCNAGITNLSDSGSEDNNESSFEDKAGNAFDFRGLLENANSLERTRDALSKRNVTATPPRSQAATMDVNALLALGENQNYQSVEVEEREGNQRKKAGRGAPAAPPTLDEPSRLSKTKSTRIKRHTKTRPVSTVVANAGDTDDSDFEEVADADLSSDQDDGETPNISGDLEIRVGLEGLRPTKEQKTQHELEMALKRRLNRDIKDRQILLHKVSLMCQIARSLKYNRLLSESDSLMQATLKLLPSRNAYPTERGTELKYLQSFVTWFKTSIKLLSPNLYSAQSPATKEAILEALLEQVKRKEARCKQDMIFIFIALARGMGMHCRLIVNLQPMPLRPAASDLIPIKLRPDDKNKSQTVESERESEDEKPKKDKKAGKPAEKESSKSTISKEAEKKNNAKKAEAKPLSKSTTKGSETTKSGTVPKVKKELSLSSKLVEKSKHQKAYTSSKSDTSFDEKPSTSSSSKCLKEEYSELGLSKKLLKPTLSSKLVLKSKNQSSFSSNKSDTSFEENPSTSSSSKSLKEETAKLSSSKLEDKKVASPAETKTKVQSSLLKRVTTQNISESGDSKKPKVAPVDTFSPVAGRTRRATVKPKTEEKPQVVGSPVIPKLMLSKVKQLNAKHSDTENASPANKHLQEQRNTRETRSRSKSPKVLISPSFLKKKSDGADSTSDPQKHQMAPETKARISPNFLSEALPARQLRSRGQKASSLAIPQLDGGDDVPLPKKRPKLEKLKNSQDSDEVFEPAKPVKKAPVLPKSVQNLRKDRRVMSTDDEGGSRLNRKTDASDMWVEVWSDVEEQWICIDLFKGKLHCVDTIRKNATPG---------LAYVFAFQDDQSLKDVTARYCASWSTTVRKARVEKAWLDETIA------PYLGRRTKRDITEDDQLRRIHSDKPLPKSISEFKDHPLYVLERHLLKFQGLYPPDAPTLGFIRG-------EAVYSRDCVHLLHSREIWLKSARVVKLGEQPYKVVK---ARPKWDRLTRTVIKDQ-PLEIFGYWQTQEYEPPTAEN-GIVPRNAYGNVELFKDCMLPKKTVHLRLPGLMRICKKLNIDCANAVVGFDFHQG-ACHPMYDGFIVCEEFREVVTAAWEEDQQVQVLKEQEKYETRVYGNWKKLIKGLLIRERLKKKYNF--------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14736-1", "uniprot_id": "RAD4_YEAST", "id": "P14736-1", "name": "DNA repair protein RAD4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MNEDLPKEYFELIRKALN------------------------------------------------------EKEAEKAPLSRRRRVRRKNQPLPDAKKKFKTGLNELPRESVVTVN----------LDSSDDGVVTVPTDDSVEEIQSSEED------------------YDSEEFEDVTDGNEVAGVEDISVEIKPSSKRNSDARRTSRNVCSNEERKRRKY-------FHMLYLVCLMVHGFIRNEWINSKR-LSRKLSNLVPEKVFELLHPQKDEELP-------------------LRSTRKLLDGLKKCMELWQKHWKITKKYDNVGLYMRTWKEIEMS---------------------------------------------------------------------------ANNKRKFKTLKRSDFLRAVSKGHG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLN--------------------GNNAYKDMVKYP----------------------------------------------------------------------------------IFWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRRYAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPG-CKECGYLKVHGKVGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVGRPKGE-------AEEEDERLYSFEDTELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFLGVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFIQEDDNRKEHLLGALESWNTLLLKLRIRSKLNSTYGKIAEEEPNVTKEQNIADNHDNTETFMGGGFLPGIANHEARPYSEPSEPEDSLDYVSVDKAEESATDDDVGEDYSDFMKELEMSEESD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .*. ... . . :.* .. . : . .: : ::. .. * . ::.:. .. .: . :. .* .: * : *:* :. .: * . * .::* : : : : : : . . : : ::: : : : : . * : . .: .* . :: . .. . . . :: . :.: * **: . . :*: :* .: . : : **.. : . :*** ** : .** *: *. : . : ** : . .: :* :: *:** *.*::.: : : : * . *: : **:: : *:* * ..*::: *. *::* *.: :. ::.. :*: * ** * * :.:* :**: :* *:* : * : .: *.:: . *:..*.*. * :*: .* :*.: :::.: :* : : : .:::: . .*: * * **.:*: *. ", "identical_positions": 78, "similar_positions": 198, "identity": "5.54%" }, { "cls_id": "homologset.agr.FB:FBgn0004784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68403-1", "uniprot_id": "KPCB_RAT", "id": "P68403-1", "name": "Protein kinase C beta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPAAGPPPSEGEE--------------------------------------STVR-FARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTER----------------------RGRIYIQAHID-REVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWN----------------------------ETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGSEGNEELRQKFE----------RAKIGQGTKAPEEKTAN----------TISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK-----PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68404-1", "uniprot_id": "KPCB_MOUSE", "id": "P68404-1", "name": "Protein kinase C beta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPAAGPPPSEGEE--------------------------------------STVR-FARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTER----------------------RGRIYIQAHID-REVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWN----------------------------ETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGSEGNEELRQKFE----------RAKIGQGTKAPEEKTAN----------TISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK-----PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05771-1", "uniprot_id": "KPCB_HUMAN", "id": "P05771-1", "name": "Protein kinase C beta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPAAGPPPSEGEE--------------------------------------STVR-FARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTER----------------------RGRIYIQAHID-RDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWN----------------------------ETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGSEANEELRQKFE----------RAKISQGTKVPEEKTTN----------TVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK-----PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY24-1", "uniprot_id": "KPCB_DANRE", "id": "Q7SY24-1", "name": "Protein kinase C beta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEPAN----SDGEER------------------------------------SAPMRGFARQGALRQKN--VHEVKNHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDD-----PRSKHKFKVHTYSSPTFCDHCGSLLYGLIHQGMRCDHCMMNIHKRCVANVPSLCGTDHTER----------------------RGRIQITAEIK-NNVLTVSIKEAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCCLNPTWN----------------------------ETFTFNLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKQGVDGWFKLLSQEEGEYFN-------------------------------VPVPPEGEEGNEELRQKFE----------RAKIGP--SKTDGSSSN----------AISKFDSNGNRDRMKLSDFNFLMVLGKGSFGKVMLAERKGADELFAIKILKKDVVIQDDDVECTMVEKRVLALSGK-----PPFLTQLHSCFQTMDRLYFVMEYINGGDLMYHIQQVGKFKEPHAVFYAAEIAIGLFFLHSKGVIYRDLKLDNVMLDAEGHIKIADFGMCKENMLDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHHVSYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIREHGFFRYMDWEKLEHREVQPPFKPKACG-RDAENFDRFFTRHPPVLTPPDQEVIMNLDQDEFEGFSFINPEFPAMEAQS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20444-1", "uniprot_id": "KPCA_MOUSE", "id": "P20444-1", "name": "Protein kinase C alpha type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADVYPANDSTASQD---------------------------------------VANRFARKGALRQKN--VHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINDPSLCGMDHTEK----------------------RGRIYLKAEVT-DEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSNLNPQWN----------------------------ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKAHNQEEGEYYN-------------------------------VPIPEGDEEGNMELRQKFE----------KAKLGPVGNKVISPSED----------RKQ---PSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLNNVMLNSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKQPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05696-1", "uniprot_id": "KPCA_RAT", "id": "P05696-1", "name": "Protein kinase C alpha type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADVYPANDSTASQD---------------------------------------VANRFARKGALRQKN--VHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEK----------------------RGRIYLKAEVT-DEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWN----------------------------ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYN-------------------------------VPIPEGDEEGNVELRQKFE----------KAKLGPAGNKVISPSED----------RKQ---PSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17252-1", "uniprot_id": "KPCA_HUMAN", "id": "P17252-1", "name": "Protein kinase C alpha type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADVFPGNDSTASQD---------------------------------------VANRFARKGALRQKN--VHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEK----------------------RGRIYLKAEVA-DEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWN----------------------------ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYN-------------------------------VPIPEGDEEGNMELRQKFE----------KAKLGPAGNKVISPSED----------RKQ---PSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PM31-1", "uniprot_id": "A0A8M9PM31_DANRE", "id": "A0A8M9PM31-1", "name": "Protein kinase C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADTQ--SNEQSSSD---------------------------------------VANRFARKGALRQKN--VHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHELVTFSCPGADKGPDTDD-----PRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDSCDMNVHKQCVMNVPSLCGTDHTER----------------------RGRLYMKIEVI-GDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLIPDPKNETKQKTKTIRSSLNPTWN----------------------------ETFTFKLKPADKDRRLAVEVWDWDRTTRNDFMGSMSFGVSELMKSPVCGWYKMLNQEEGEYYN-------------------------------VPIPDEDDP-DTELRQKFEDETL-EDLEQIAKLGPP-KKNITALDD----------SGSSI-TSSNVDNVRLSDFNFLAVLGKGSFGKVMLAEMKSSDELFAIKILKKDVVIQDDDVECTMVEKRVLAQQDK-----PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHKKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENIVEGVTTRTFCGTPDYIAPEIIAYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYSKTLSKEAVSICKGLMTKHPSKRLGCGQEGERDIREHAFFRRIDWDRLANREVQPPFKPKVCG-KGAENFDKFFTRTQPQLTPPDELVIANIDQADFDGFTFVNPQFVHPSLVNTE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AR84-1", "uniprot_id": "A0A8M3AR84_DANRE", "id": "A0A8M3AR84-1", "name": "Protein kinase C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADHL--IQINDSSA---------------------------------------GVNRFARKGALRQKN--VHEVKNHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVSFSCPGADKGPDTDD-----PRSKHKFKIHSYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVMNVPSLCGTDHTER----------------------RGRIFMKIEVS-GDRLHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPKNETKQKTRTIRSSLNPTWN----------------------------ESFIFKLKASDKERRLSVEVWDWDRTTRNDFMGSMSFGVSELIKAPVSGWYKMLNQEEGEYYN-------------------------------VPIPEENDI-NLELRQKFEACQFNIHLLKKAKLGPG-KKVITPTDH----------RRFSL-PSGNMDKVRLNDFHFLALLGKGSFGKVMLAEMKSTEELYAIKILKKDVVIQDDDVECTMVEKRVLAQREK-----PPFLTQLHSCFQTVDRLYFVMEYINGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHRKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENMYEGMTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLTKEAVSICKGLMTKHPSKRLGCGAEGERDIKEQAFFRRIDWDRLANREIQPPFKPKVCG-KAAENFDKFFTRTQPMLTPPDQLVIANIDQSEFAGFSFINPEFIHPASIHSVV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63318-1", "uniprot_id": "KPCG_MOUSE", "id": "P63318-1", "name": "Protein kinase C gamma type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGLGPGGGDSEGGP----------------------------------------RPLFCRKGALRQKV--VHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDD-----PRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTER----------------------RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWN----------------------------ETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYN-------------------------------VPVAD---ADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSPT--------DSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCG-RSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63319-1", "uniprot_id": "KPCG_RAT", "id": "P63319-1", "name": "Protein kinase C gamma type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGLGPGGGDSEGGP----------------------------------------RPLFCRKGALRQKV--VHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDD-----PRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTER----------------------RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWN----------------------------ETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYN-------------------------------VPVAD---ADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSPT--------DSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCG-RSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05129-1", "uniprot_id": "KPCG_HUMAN", "id": "P05129-1", "name": "Protein kinase C gamma type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGLGPGVGDSEGGP----------------------------------------RPLFCRKGALRQKV--VHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDD-----PRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTER----------------------RGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWN----------------------------ETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYN-------------------------------VPVAD---ADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSPT--------DPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCG-RSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQZ0-1", "uniprot_id": "A0A8M1QQZ0_DANRE", "id": "A0A8M1QQZ0-1", "name": "Protein kinase C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTPVSPSPSLSPLALSSPSPSSSPLPSP------------------------------LSPPPRLPVFQRKGALKHKR--VIEVKDHQFTARFFKQPTFCSHCTDFIWGIGKQGFQCQVCSFVVHKRCHEFVTFTCPGAITAPKPED-----LKSKHKFKVHTYSSPTFCDHCGSLLYGLIHQGMKCGCCDMNVHKRCESSVPSLCGQDHTEK----------------------RGRIRLTVRGE-KEDIYITVHEALNLIPMDPNGLSDPYVKLKLIPDPKSHSKQKTKTIRSTLNPIWN----------------------------ESFTFSVRGRQWDRRLSVEVWDWDRTSRNDFMGALSFGVSEIFRRSVSGWFKLLNQDEGEYYN-------------------------------IPVPDPDLQVPEEILMPSIP----------PTPSPVTTPVPAVTPPAL--------SPAPAVLHTGKGHIGLHDFNFLMVLGKGSFGKVLLAEEKGSERLFAIKMLKKDVLFQDEDTESAMVERRVLALSGR-----PHFLTSLYCAFQTEDRLYYVMEYVNGGDLMFHIQIVGKFKEPHAAFYAAEIAVGLFFLHNKGIIYRDLKLDNVLLDSEGHIKIADFGMCREGMMEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWSYGVLLYEMLAGQPPFDGIDEEELFQSIMEQSVSYPKSLSREAVAICKGLLTKNPAKRLGGGEDAERELREHPFFRWIDWDRLERLEIQPPFKPRSGG-KKGENFDKFFTSTSSALTPSDPDVLAAINQEEFQDFTFMNSEFPPSPLTAV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13677-1", "uniprot_id": "KPC2_DROME", "id": "P13677-1", "name": "Protein kinase C, eye isozyme", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAVATPGATVLPPSVPSAAPGAKAPAAGAGKGPGNLLEIT---------------------GEANIVNYMKNRLRKGAMKRKG--LEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKCPGKDTDFDADC-----AKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMCGADISEV----------------------RGKLLLYVELK-GNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFN----------------------------ETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQVEGEHYN-------------------------------IPCVD-AFNDIARLRDEVR-----------HDRRPNEKRRMDNKDMP--------------HNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGR-----PPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEFITII-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLR---YTGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKT---KHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPS-VLTTSQQEEFRGFSFMPDDLDL---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**: .: : :.*:* : * : *.:* **: *:**: * * *::* * * . . : * : : ..:* .** :* *: :* * : * * * :** . .:: . : *: .: .. . . :*:: : :. : .: : . : * : . : : : . : . *: : .* .** : . . : :* :: ::***.****:*:. :.::.* *:*:*:** :.* .* : . *:::: : **..::. *** :*:::.**: *****:*:* ::. * ***.*: :.* ::: ..:*******:*::* ***:*:.*:*:.:: : * ******:::****: : * :.***::****:::: *.**.* ** :*. * . :. :: * : : .::**.* :*** * : . *** :::: .: ** * . . *: ** *** .: :* :* .*:: :: ", "identical_positions": 143, "similar_positions": 187, "identity": "12.18%" }, { "cls_id": "homologset.agr.FB:FBgn0004795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGC2-1", "uniprot_id": "D3ZGC2_RAT", "id": "D3ZGC2-1", "name": "AT-rich interactive domain-containing protein 3", "aln": "MILMSREPVCLLGCAQVESHASLWVKPETVMEPLQQQQ-KQPQQTPLQMDAREKQGSHTREAQFLYAPKLGTQPALLSVTPGRPSG---SPVLGPLGRVLPATPAARVSEQSNVNSE---------------PEEEEGGLEDEDGDDDVTEVAEKEAQAASKYFHMQKATRQEPRAAPMSSLLPAPGLPP--QGQ-TKEDHTKDASKAP-------------------------------------------PSVPTAGQPSWNLDEQLKQNGALAWSDDADGGRGREISRDFA---KLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSS-LFGYSP--AAAAAAAAAAAAASAASAGAPALLSPPKIRFSILGLGSS--SGTNTSSPRIPPASTLRKGDGVP---VPVPNR---------LAVSGPLAGQQAGNRTGTLEQLRERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRINGR-EDRAETSAAALNLTTSNIGSINMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIDGITYTGVLFAQKPVVHLIAGSAP---QSIGSSASSSSSSSSSSSSSHCSPSPTSSRGTPSAEPSTSWSL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1N7-1", "uniprot_id": "ARI3B_MOUSE", "id": "Q9Z1N7-1", "name": "AT-rich interactive domain-containing protein 3B", "aln": "------------------------MEPLQQQQ-QQQQQ-KQPQQPLLQMDAREKQGPQTRESQFLYASKLGTQPALLSITPGRPSG---SSVLGPLARVPPATPVARMSEQSNVNSE---------------PEEEEGGLEDEDGDDDVAEVAEKEAQAASKYFHMQKVTRQEPRATPMSSLLPVPGLSP--QGQQTKEDHTKDASKAP-------------------------------------------PSVPTAGQPSWSLDEQLKQNGALAWSDDADGGRGREISRDFA---KLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSS-LFGYSPAAAAAAAAAAAAAAASAASAGTPALLSSPKIRFSILGLGSS--SGTSASSPRIPPASTLRKGDGVP---VPVPNR---------LAVSGTLAGQQAGNRPGPLEHLRERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRINGR-EDRAEPSAPALNLTTSNIGSINMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIDGTTYTGVLFAQKPVVHLIAGSTP---QSIGSSASSSNSSS-----SHCSPSPTSSRGTPSAEPSTSWSL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVW6-1", "uniprot_id": "ARI3B_HUMAN", "id": "Q8IVW6-1", "name": "AT-rich interactive domain-containing protein 3B", "aln": "------------------------MEPLQQQQQQQQQQQKQPHLAPLQMDAREKQGQQMREAQFLYAQKLVTQPTLLSATAGRPSG---STPLGPLARVPPTAAVAQVFERGNMNSE---------------PEEEDGGLEDEDGDDEVAEVAEKETQAASKYFHVQKVARQDPRVAPMSNLLPAPGLPP--HGQQAKEDHTKDASKAS-------------------------------------------PSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREISRDFA---KLYELDGDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSS-LFGYSP-----------AAATAAAAAGAPALLSPPKIRFPILGLGSS--SGTNTSSPRISPATTLRKGDGAPVTTVPVPNR---------LAVPVTLASQQAGTRTAALEQLRERLESGEPAEKKASRLSEEEQRLVQQAFQRNFFSMARQLPMKIRINGRAEDRAEASAAALNLTTSSIGSINMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIDGTTYAGVLFAQKPVVHLITGSAP---QSLGSSASSS-SSS------HCSPSPTSSRGTPSAEPSTSWSL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99856-1", "uniprot_id": "ARI3A_HUMAN", "id": "Q99856-1", "name": "AT-rich interactive domain-containing protein 3A", "aln": "--------------MKLQAVMETLLQRQQRARQELEARQQLPPDPPAAPPGRAR-AAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGPPGSEEEDAAREGTPGSP---GRGREGP----GEEHFEDMASDED-MKPKWEEEEMEEDLGEDEEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGV-----------------------------------------PRVLGGQERPGPGPAHPGGAAHVAPQLQPPDHGDWTYEEQFK---QLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGS-LFAYSP-------------------GGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPG-RLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSN-SISMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTG--TSGGQAGPAGLSTPSTS-TSNNSLP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62431-1", "uniprot_id": "ARI3A_MOUSE", "id": "Q62431-1", "name": "AT-rich interactive domain-containing protein 3A", "aln": "--------------MKLQAVMETLIQRQQRARQELEARQAPPPPPPEPTGVRARTTMTDEDREPENARMHRTQMAALAAMRAAAAGLGHPSSPGGSEDGPPISGDEDTAREGTLSSPALHGSVLEGAGHAEGDRHLMDVGSDDDDTKSKWEEQELEE-LGEEEEEEEEEDDFEEEEEEEEGLGPPESASLGTAGLFTRKAPPAQAFRGDGG-----------------------------------------PRMLSGPERLGPGPAHP---SHMASQMPPPDHGDWTFEEQFK---QLYELDADPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECERRGLSSPNELQAAIDSNRREGRRQSFGGS-LFAYSP-------------------SGAHSMLPSPKLPVTPLGLAASTNGSSITPAPKIKKEEDSAIPITVPG-RLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESTEPPEKKMALVADEQQRLMQRAVQQSFLAMTAQLPMNIRINSQASESRQDSAVSLTSANGSN-SISMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEMNGIVYTGVLFAQPPPPTAPSAPGKGGVSSIGTNTTTGSRTGASGSTVSGGQVGLPGVSTPTMSSTSNNSLP-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BEA6-1", "uniprot_id": "ARI3A_DANRE", "id": "A2BEA6-1", "name": "AT-rich interactive domain-containing protein 3A", "aln": "------------------MVDNTSIATKSALQAAFSSASSLPLLVSSPGAHGQSGGGGGMKLEAVMENLQRQQAARLALEEKLRQAEKEKDIRSMVESQIQQQALAFRHYQAAVRGAFAAGVPNSSS----GHPLERRAESDIDDEDDEDDDPELDRGMDDEERDMDEDDSMNEGGGDEDLEGPLAHYPP-RHAVYPGAGQSPKST----------------------------------------------PIHLSRVQPPYPAPRQAESPSALAPQAQS-QHHEWTYEEQFK---QLYELDDDEKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLYTLYKLVTEKGGLVEVINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSSPGELQAAIDSNRREGRRQSYGST-LFNYSP-------------------VGTPTLLASPKLQMPHISMPTP-NGGHMTQTPGIKKE-DSMLSSCLTN-RVGIPMS-------LAGHHSAAQAAAAAAVQAAALEQLREKLESGEPPEKKVMLMAEEQQRIMQHALQQNLFAMATQLPMNIKLNNRD--DRQETALNLS-TNGIS-SINMS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEINGVVYTGVLFARKPAIGFMPSSQR-----VHHQHSSQGKSNSPG---LSSHIQPSSSASSSASSHGPATSP-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZQB1-1", "uniprot_id": "D3ZQB1_RAT", "id": "D3ZQB1-1", "name": "AT-rich interactive domain-containing protein 3", "aln": "-----------------------------------------------------------------MEALQRQQAARLAQGVGPLAP-----------PRLPLP-QPPLLGARTLQAP----------------------------EGALGVVGAEEEEGAEEDEEG-ETPLVEEETAEQSHPGARCPNSP-------------------------------------------------------------------------------------SGQSPGIQPHEWTYEEQFK---QLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTTVPLFNLAG--------------------PTPRGAPGPASSHGPAPTTTP-------NCPGSTQGSASGLPAHACAQLSPSPVK---------KEESGIPPPRLAIPVGLALEAAREKLAPEEPPEKRAVLMGPMDP--PRLGATPSFLPRGKAPLREERLDGP-----------LNLAGSGISSINMA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEINGVVYTGILFARRQPVPASLGPTN--------------------------PPPPPSTGPPSSTLP-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6PWV5-1", "uniprot_id": "ARI3C_MOUSE", "id": "A6PWV5-1", "name": "AT-rich interactive domain-containing protein 3C", "aln": "-----------------------------------------------------------------MEALQRQQAARLAQGVGPLAP-----------PRLPLP-QPPLLGARTLQAP----------------------------EGAIGVVGAEEEEGAE-DEEG-ETPLAEEETAEQSHPGARCPNSP-------------------------------------------------------------------------------------SSQSPGIQPHEWTYEEQFK---QLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTAVPLFNLAG--------------------PTPRGAPGPASSHGPAPTATP-------NCPGPTQGSASGLPAHACAQLSPSPVK---------KEESGIPPPRLALPMGLASEATREKLAPEEPPEKRAVLMGPVDS--PRLGAPPSFLPRGKAPLREERLDGP-----------LNLAGSGISSINVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEINGVVYTGILFARRQPVPASLGPTN--------------------------PPPLPSTGPPSSTLP-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKF2-1", "uniprot_id": "ARI3C_HUMAN", "id": "A6NKF2-1", "name": "AT-rich interactive domain-containing protein 3C", "aln": "-----------------------------------------------------------------MEALQKQQAARLAQGVGPLAP-----------ACPLLPPQPPLPDHRTLQAP----------------------------EGALGNVGAEEEEDAEEDEEKREEAGAEEEAAEESRPGAQGPSSP-------------------------------------------------------------------------------------SSQPPGLHPHEWTYEEQFK---QLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTATPLFGLAG--------------------PPPRGAQDPALGPGPAPPATQ-------SSPGPAQGSTSGLPAHACAQLSPSPIK---------KEESGIPNPCLALPVGLALGPTREKLAPEEPPEKRAVLMGPMDP--PRPCMPPSFLPRGKVPLREERLDGP-----------LNLAGSGISSINMA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEINGVVYTGVLFARRQPVPASQGPTN--------------------------PAPPPSTGPPSSILP-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24573-1", "uniprot_id": "DRI_DROME", "id": "Q24573-1", "name": "Protein dead ringer", "aln": "------------MQLRVHPTMDCSGRSTSNIERDSDLGDDLSHGDRTDDEMRDCDSVDGEHHQLSAKAAIAARLSHTVSGGGGSFASPEPQTELPLSHHHQLPPNHPLNALGSFMGIGGLHSIPNLQHSDVLEKLKMQVRDMKVGLMEQDYAAAAHAAAFGANMLPTTISSGFPLPHNSVAFGHVTSSPSGGNGSSYNGGTTPTNSSNSNATTNGGGTAGPGGTGGSGGGGGGGGGGGGGVGGHQFSFASPTAAPSGKEARHFAANSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMPMTPISRPSLPGGMQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQMPNLVKQEIESRMMEYLQLIQAKKEQGMPPVLGGNHPHQQQHSQQQQQQQHHHQQQQQQQSQQQHHLQQQRQRSQSPDLSKHEALSAQVALWHMYHNNNSPPGSAHTSPQQREALNLSDSPPNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFHHPSMGHQQDAASEGEPEDDYAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLDKSDDSAIENSPTTSTTTGGSVGHRHSSPVSTKKKGGAKPQSGGKDVPTEDKDASSSGKLNPLETLSLLSGMQFQVARNGTGDNGEPQLIVNLELNGVKYSGVLVANVPLSQSETRTSSPCHAEAPTVEEEKDEEEEEEPKAAEEESHRSPVKQENEDVDQDMEGSEVLLNGGASAVGGAGAGVGVGVPLLKDAVVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . ..:* :***:: * :********* ********:**:*****.:***: *: ** :****::**:*:*:*: :** **::*****************.**** : **.* *******.******* :: : . : * :.: : .::: : . :. : :. . .:: ::::* *:*:*.*. . . . ", "identical_positions": 92, "similar_positions": 68, "identity": "9.97%" }, { "cls_id": "homologset.agr.FB:FBgn0004811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8N8-1", "uniprot_id": "G3V8N8_RAT", "id": "G3V8N8-1", "name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "aln": "MEAGRTAVLRVKRKRNAEPAEALVLACKRLR--SGEVESSAPETPEGQETG-AERN------VFQLVATVRSQE-PIQQLVRAALR----------PSRSSQLRIRRDLR-----ASVREVRKEGRYRVVSSHRS---------SGTSNS-LEPQCVS---EAVRDG----GFQLLDLVHEEEDPEAAATDCRKTSDPDVILCNSVELIRERLTVSEDGSQVEHQEEPKHSDDYVYDIYYMEMAPPGWIENILSVQPYSQEW-------ELVNDDEQ-----------PEDIYEDEDDENSENNWRNEYPDEESSDRDEDSRGSDEYNSLSDEER-SCRRLVWSKYPLDVQKEFGYDSPHD------LDSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPE5-1", "uniprot_id": "S7A6O_MOUSE", "id": "Q7TPE5-1", "name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "aln": "MEAGRTAVLRVKRKRNAEPAEALVLACKRPR--SSEVESAARETPEGQEAAAAERN------VFQLVATVRSQEEPIQQLVRAALR----------PSRSSQLRIRRDLR-----ASVREVRKEGRYRVVSSHRS---------SGTSNS-LEPQCGS---EAVGDA----GFQLLDLVHEEENPEAAATDCRKTSDPDVILCNSVELIRERLTVSEDGSQVNHQEDPKHNDDYVYDIYYMEMAPPGWIENIMSVQPYSQEW-------ELVNDDEQ-----------SEDIYEDEDDENSENNWRNEYPDEESSDRDEDSRGSDEYNSLSEEER-SCERLMWSKYPLDVQKEFDYDSPHG------LDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CW6-1", "uniprot_id": "S7A6O_HUMAN", "id": "Q96CW6-1", "name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "aln": "MEAARTAVLRVKRKRSAEPAEALVLACKRLR--SDAVESAAQKTSEGLERA-AENN------VFHLVATVCSQEEPVQPLLREVLR----------PSRDSQQRVRRNLR-----ASAREVRQEGRYRVLSSRRS---------LGTTSSGQESEYTPGNPEAAGNS----GFQLLDLVHEEGEPEAASAGSCKTSDPDVILCNSVELIRERLTVSEDGPGVRRQEEQKH-DDYVYDIYYLETATPGWIENILSVQPYSQEW-------ELVNDDQE-----------PEDIYDDEDDENSENNWRNEYPEEESSDGDEDSRGSADYNSLSEEERGSSRQRMWSKYPLDVQKEFGYDSPHD------LDSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3I2-1", "uniprot_id": "S7A6O_DANRE", "id": "Q5U3I2-1", "name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "aln": "MDPS-TTILRVKRKRGTDPADALLLACKRIRPEATAAQPSDESEPEPQEPK-IENS------VFKLVATVVSQDAPVQPHVREALARPRLAHHALRPSQGSSQRIIGDLR-----SVKWSTRREERYRILSSHRAGLPSEPAPAGGGGEENHDSHAESR--DGLPLG----EVQVFDILHEEED--VKVPGKMVVSDPETILCNSVKMIREKLSVSGAGLGTEHRE---KEDDYVYDLYYQETATPGWIQDILSVRPYSQEG-------ELVPDEVAW----------EEEVYEDEDDENAEANWRNDYP-EESSEGD--SEGEERYGGCWSEEH-SYSRRSRECYRRDMIDELENDKDEDDEEREYNDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIR9-1", "uniprot_id": "Q9VIR9_DROME", "id": "Q9VIR9-1", "name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "aln": "----MPAVVRIKRRIDEEPQTAFVLNGKRRRLHNDENALEDAGAVAGAVAGAVASDKDELTTVLKFAGTLEKQDDCATRKFAAARLNKAAARDLVQQQRSNDAAIASALRRDRQRQEAQENSREQRFRVVNCLRSTLENSAAEAECPESQSHESSSHITIVDIESQQQQHMGTASAAAEEQQQQEIAPSQDQQQPADSDVGYVYDLYVPENEMQAAYVDMMDDNYLSVIPVGEIVLEDCYNDQDEDYDSEDSNQENYFTNDYPDDDEAGAMGSDDELCRQMNKFMLDDDEDEFASTSDDDDYATFRDPYVHTIDTEEDSFVDDVDFYNVDRERGSAYERYKRRILKELEGQEEEDEDDDDDDDSFASADGE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:::*:**: . :* *::* ** * . *:::..*: .*: . . .:... : ** . :* *:*::.. *: .. :. : .:: : . . :*.:. .: : .:.: .: . . .: * : * : :: . . :::: : *: *: : . .*:: .:*: * .:: * . *. .. : .* *. .. *.:", "identical_positions": 31, "similar_positions": 98, "identity": "8.36%" }, { "cls_id": "homologset.agr.FB:FBgn0004828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84244-1", "uniprot_id": "H33_MOUSE", "id": "P84244-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXT2-1", "uniprot_id": "H3C_HUMAN", "id": "Q6NXT2-1", "name": "Histone H3.3C", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVK-PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C0HL67-1", "uniprot_id": "H33B_DROME", "id": "C0HL67-1", "name": "Histone H3.3B", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6PI20-1", "uniprot_id": "H33_DANRE", "id": "Q6PI20-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P84243-1", "uniprot_id": "H33_HUMAN", "id": "P84243-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84245-1", "uniprot_id": "H33_RAT", "id": "P84245-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZK97-1", "uniprot_id": "D3ZK97_RAT", "id": "D3ZK97-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLATKATRKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61830-1", "uniprot_id": "H3_YEAST", "id": "P61830-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:**:***:*** *** ****:***********:************************:*******:*:*****: *****.*:*****.********* ***:****:****:", "identical_positions": 116, "similar_positions": 15, "identity": "85.29%" }, { "cls_id": "homologset.agr.FB:FBgn0004832", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0X7-1", "uniprot_id": "A0ABK0M0X7_RAT", "id": "A0ABK0M0X7-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "----------------MPVSPRSQAIPVVPCAWHIYGAELSVLQPLNKPAPSPTPAPSRTAPDPVFYMRRACFPAQSRLTP-----------AEPRTLELTRLGVTSIKAA-----------PKVIDTKGGFILEE----------EEEEKHKIGD-------------------VVHEPGPVMEFDYTICEECG-KEFMDSYLMNHFDLPTCDSCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPALRFIVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWK-----RET-TAHQHEYG-PEEH-LEEDMY---RKTCTLCGHELTYEKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64267-1", "uniprot_id": "XPA_MOUSE", "id": "Q64267-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "----------------MATAEEKQTSP----------------EPVAADEPAQLPAAVRASVE--RKRQRALMLRQARLA------------ARPYPAAAATGGVASVKAA-----------PKMIDTKGGFILEE----------EEE-KHEIGN-------------------IVHEPGPVMEFDYTICEECG-KEFMDSYLMNHFDLPTCDSCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPALRFLVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKFDKKVKELRRAIRSSVWK-----RET-TTHQHKYG-PEEN-LEDDMY---RKTCTLCGHELTYEKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23025-1", "uniprot_id": "XPA_HUMAN", "id": "P23025-1", "name": "DNA repair protein complementing XP-A cells", "aln": "----------------MAAADG--ALP----------------EAAALEQPAELPASVRASIE--RKRQRALMLRQARLAAR----------PYSATAAAATGGMANVKAA-----------PKIIDTGGGFILEE----------EEEEEQKIGK-------------------VVHQPGPVMEFDYVICEECG-KEFMDSYLMNHFDLPTCDNCRDAD-DKHKLITKTEAKQEYLLKDCDLEKREPPLKFIVKKNPHHSQWGDMKLYLKLQIVKRSLEVWGSQEALEEAKEVRQENREKMKQKKFDKKVKELRRAVRSSVWK-----RET-IVHQHEYG-PEEN-LEDDMY---RKTCTMCGHELTYEKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28518-1", "uniprot_id": "XPA_DROME", "id": "P28518-1", "name": "DNA repair protein complementing XP-A cells homolog", "aln": "---------------MSAEVSTNESAP-------------------PAEKKSKLTNAQKARIE--RNQAKAQKLREAKLVSHPFKELASNKEGGTHPEAALSQGSSVIKVQG----------TKYIDSGGGFLLEQPVMPTG---VGPAGLNKSGEEAP----------------PILDDAIAIPVQYEECLECG-DMFADSYLFNNFGHSVCDKCRDKD-ERYALITRTEAKAEYLLKDCDFDKREPKLRYISRKNPHNVRWGEMKLYLHLQIHQRALEVWGSEEELVRQHEAREDKREEGKARKYNKKMKQLRMEVRSSIYT-----KKTHEVHEHEFG-PDTYDEEEDTY---THTCITCPYSETYEKM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28519-1", "uniprot_id": "RAD14_YEAST", "id": "P28519-1", "name": "DNA repair protein RAD14", "aln": "MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTRPLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDKRPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELND-EDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQEYTNRLREKKHGKAHIHHFSDPVDGGIDEDGYQIQRRRCTDCGLETEEIDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. ::. . :: .. : **:: : : *. . * ** . *. * : * .*..* . . ::: *:*:**.* :*:*.* :::. * :: : : **: :. *:*::: :: ::: **.:* * : *:: : . : :*::**:*::* *:. :. :: .* *.:. * ::* * : * * . .:", "identical_positions": 42, "similar_positions": 88, "identity": "11.29%" }, { "cls_id": "homologset.agr.FB:FBgn0004837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06330-1", "uniprot_id": "SUH_HUMAN", "id": "Q06330-1", "name": "Recombining binding protein suppressor of hairless", "aln": "----------------------------MDHTEGSPAEEPPAHAPSPGKFGERPPP----------------------------------------------KRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHC-SAAGAILRA----NSSQVP--PNESNTNSEGS-------------YTNASTNSTSVTSSTATVVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31266-1", "uniprot_id": "SUH_MOUSE", "id": "P31266-1", "name": "Recombining binding protein suppressor of hairless", "aln": "--MPSGFPQSPRTSPRARPKTRITGALPMDYSEGLSAEERPAHAPSAGKFGERPPP----------------------------------------------KRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPEPGPRPHC-SAAGAILRA----NSSQVP--SNESNTNSEGN-------------YTNASTNSTSVTSSTATVVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFG7-1", "uniprot_id": "A0A8I6AFG7_RAT", "id": "A0A8I6AFG7-1", "name": "Recombining binding protein suppressor of hairless", "aln": "-----------------------------------------MAPVVTGKFGERPPP----------------------------------------------KRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHC-SAAGAILRA----NSSQVP--TNESNTNSEGN-------------YTNASTNSTSVTSSTATVVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28159-1", "uniprot_id": "SUH_DROME", "id": "P28159-1", "name": "Suppressor of hairless protein", "aln": "MKSYSQFNLNAAAPPAIAYETTVVNPNGSPLDPHQQQQQQSQDMPHFGLPGPQPPSSQQQQQQLQVHHQQQQQQQQQQQQQQHQQQMQMSLLPGPYRPHIEEKKLTRDAMEKYMRERNDMVIVILHAKVAQKSYGNEKRFFCPPPCIYLFGSGWRRRYEEMLQQGEGEQGAQLCAFIGIGSSDQDMQQLDLNGKQYCAAKTLFISDSDKRKHFMLSVKMFYGNGHDIGVFNSKRIKVISKPSKKKQSLKNADLCIASGTNVALFNRLRSQTVSTRYLHVENGHFHASSTQWGAFTIHLLDDNESESEEFQVRDGYIHYGATVKLVCSVTGMALPRLIIRKVDKQMALLEADDPVSQLHKCAFYMKDTDRMYLCLSQEKIIQFQATPCPKEPNKEMINDGACWTIISTDKAEYQFYEGMGPVASPVTPVPIVNSLNLNGGGDVAMLELSGDNFTPHLQVWFGDVEAETMYRCTETLLCVVPEISQFRGEWLWVRQPTQVPISLVRNDGIIYATGLTFTYTPEPGPRPHCNTQAEDVMRARQNNNNNNITSISNNNNSNNAGSPAAGGGLQQQQQQHQALPSISEVQWNSHGSGLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :**. *:***:**.:*::**.* .::***********************:**:****::: *:* ::* .** :* *******.***:****:*:**:**:****:********************..***** ****************************:********************.*:***** ***** ******:***.*** ********* ************************ ***:**************:***:*********:************ *********.*********** ******** :******:*:**:************:*:****:*:************** *::*****:** ** * *****.***::******:**:*.*************** : * ::** *..::. .*:.*:*. *. : .: * .* .: :*", "identical_positions": 365, "similar_positions": 79, "identity": "61.45%" }, { "cls_id": "homologset.agr.FB:FBgn0004838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JII5-1", "uniprot_id": "DAZP1_MOUSE", "id": "Q9JII5-1", "name": "DAZ-associated protein 1", "aln": "------------MNS-AGADEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASRPHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRSDSSKSNKIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRAEPRD----------SKNQAPGQPG--ASQWGSRVAPS----AANGWAGQPPPTWQQGY-----GPQGMWVPAGQAIGGY---GPP-PAGRGAPPPPP-PFTSYIVSTPP---GGFPPPQGFP-QGYGAP--PQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQPDFPYGQYG--------------------------------------------------YGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGPPAGGSGFGRGQNHNVQGFHPYRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EP5-1", "uniprot_id": "DAZP1_HUMAN", "id": "Q96EP5-1", "name": "DAZ-associated protein 1", "aln": "------------MNN-SGADEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASRPHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRSDNSKSNKIFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRAEPRD----------SKSQAPGQPG--ASQWGSRVVPN----AANGWAGQPPPTWQQGY-----GPQGMWVPAGQAIGGY---GPP-PAGRGAPPPPP-PFTSYIVSTPP---GGFPPPQGFP-QGYGAP--PQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQPDFPYGQYAG-------------------------------------------------YGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGPPAGGSGFGRGQNHNVQGFHPYRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q795-1", "uniprot_id": "A0A8M9Q795_DANRE", "id": "A0A8M9Q795-1", "name": "DAZ-associated protein 1", "aln": "MSALPSTTLATEMNSNLAGDEIGKLFVGGLDWSTTQETLRNYFSQYGEVVDCVIMKDKSTNQSRGFGFVKFKDPNCVRTVLDTKPHNLDGRNIDPKPCTPRGMQPEKTRTKDGWK-GSKSDSNKSKKIFVGGIPHNCGEAELRDYFNRFGVVTEVVMIYDAEKQRPRGFGFITFEAEQSVDQAVNMHFHDIMGKKVEVKKAEPRD----------SKAPAPGQLG--ANQWGPRAIIS----AANGWAAQPAPTWQQSY-----GPQGVWVSTGQPLAGY---GPPLPAGRGAPAQAPSPFNAFLVAAPPT--GGFGAPQGYPQQGFSTQ--PQFGYSFG--TPQGDQFVAQGMPPPPATPGAGPLGFAP-ATTPSQDLSKAAPAQPDFSYSQYEYLLRCSTEEGKPFMVELQEGLGNYPQDPSAYGPTRPSHTYVQEEQGYSAGYGQDLSAFGHSFADPSQPTASYAAAPSAPSSGAPAAASSFGRGQNHNVQGFHPYRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48809-1", "uniprot_id": "RB27C_DROME", "id": "P48809-1", "name": "Heterogeneous nuclear ribonucleoprotein 27C", "aln": "----------------MEEDERGKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQNGPHTLDGRTIDPKPCNPRTLQ--------------KPKKGGGYKVFLGGLPSNVTETDLRTFFNRYGKVTEVVIMYDQEKKKSRGFGFLSFEEESSVEHVTNERYINLNGKQVEIKKAEPRDGSGGQNSNNSTVGGAYGKLGNECSHWGPHHAPINMMQGQNGQMGGPPLNMPIGAPNMMPGYQGWGTSPQQQQYGYGNSGPGSYQGWGAPPGPQGPPPQWSNYAGPQQTQGYGGYDMYNSTSTGAPSGPSGGGSWNSWNMPPNSAGPTGAPGAGAGTATDMYSRAQAWATGGPSTTGPVGGMPRTGPGNSAS----------------------------------------------KSGSEYDYGGYGSGYDYDYSNYVKQEGASNYGAGPRSAYGNDSSTQPPYATSQAV----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ********.*.****.* **.::*:::***:**:: :.:*******.* **. * ** . **.****.******.** :* :.... . *:*:**:* * *::** :*:::* *****::** **::.*****::** *.**::..* :: :: **:**:*:***** : * *: * ..:**.: . ** . *. . . * ** ... * ** ** * ***. . * : : * *: : : . .: *. . .:. :. . * * . * ..: . . : . . : . . * .: * ..:* .: . . ... :. .* ... . : .. ", "identical_positions": 124, "similar_positions": 123, "identity": "24.75%" }, { "cls_id": "homologset.agr.FB:FBgn0004839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALM9-1", "uniprot_id": "A0A8I6ALM9_RAT", "id": "A0A8I6ALM9-1", "name": "Inactive tyrosine-protein kinase 7", "aln": "MGRAWRGALLP--MPARRARVPPCKFRGKAGTPDGPTGAHSAIVFIKEPSSQDALQGRRALLRCEVEAP-DPVHVYWLLNGVPVQDTERRFAQGSSLSFAAVDRLQDSGAFQCVARDNITGEEARSANASFNIKWIEAGPVVLKHPASAAEIQPQTQVTLRCHIDGHP----RPTYQWFRDGTPLSDDQSTHTVSSKERNLTLRPASPEHSGLYSCCAHNAFGQACSSQNFTLSIADESFARVLLAPQDVVVARNEEAMFHCQFSAQPPPSLQWVFEDETPITNRSRPPHLRKAMVFANGSLLLTQVRPRNAGVYRCIGQGQRGPPIVLEATLHLAEIEDMLPLEPRVFIAGGEERVACPAPQGLPTPSVWWEHAGVRLPAHGRVHQKGLELVFATIAESDAGVYTCHAANLAGQRRQDVN--ITVATVPTWLRKPQDSQLE-EGKPGYLHCLTQATPKPTVIWYRNQMLISEDSRFEVSKNGTLRINSVEVYDGTVYRCVSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTVKWVR------ADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNEPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLRCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGSYTCIAGNSCNIRHTEAPLLVVDKPLMEDSEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPTATNKRHSTGDKMHFPRASLQPITTLGKSEFGEVFLAKAQGLDEGATETLVLVKSLQ-NKDEQQQLDFRREFEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKNKDEKLKS-----QPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAVLEGDFSTKSDVWAFGVLMWEVFTHG-EMPHGGQGDDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALNPKDRPSFSEIASTLGDGPADSKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKG3-1", "uniprot_id": "PTK7_MOUSE", "id": "Q8BKG3-1", "name": "Inactive tyrosine-protein kinase 7", "aln": "MG------ARP--LTLLRALLLP-----------LLAGAQAAIVFIKEPSSQDALQGRRALLRCEVEAP-DPVHVYWLLNGVPVQDTERRFAQGSSLSFAAVDRLQDSGAFQCVARDNVTGEEVRSTNASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP----RPTYQWFRDGTPLSDDQSTHTVSSRERNLTLRPASPEHSGLYSCCAHNAFGQACSSQNFTLSVADESFARVVLAPQDVVVARNEEAMFHCQFSAQPPPSLQWVFEDETPITNRSRPPHLRRAVVFANGSLLLTQVRPRNAGVYRCIGQGQRGPPIVLEATLHLAEIEDMLPFEPRVFIAGDEERVTCPAPQGLPTPSVWWEHAGVPLPAHGRVHQKGLELVFVTIAESDTGVYTCHASNLAGQRRQDVN--ITVATVPTWLRKPQDSQLE-EGKPGYLHCLTQATPKPTVIWYRNQMLISEDSRFEVSKNGTLRINSVEVYDGTLYRCVSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTVKWVR------ADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNEPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLRCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGSYTCIAGNSCNIRHTEAPLLVVDKPVMEDSEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPPATNKRHSAGDRMHFPRASLQPITTLGKSEFGEVFLAKAQGVEEGATETLVLVKSLQ-SRDEQQQLDFRREVEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKNKDEKLKS-----QPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLISAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAVLEGDFSTKSDVWAFGVLMWEVFTHG-EMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSFSEIASTLGDSPADSKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13308-1", "uniprot_id": "PTK7_HUMAN", "id": "Q13308-1", "name": "Inactive tyrosine-protein kinase 7", "aln": "MGAARGSPARPRRLPLLSVLLLP-----------LLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAP-GPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHP----RPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVN--ITVATVPSWLKKPQDSQLE-EGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWER------ADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQ-SKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKS-----QPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHG-EMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AWJ9-1", "uniprot_id": "PTK7_DROME", "id": "Q6AWJ9-1", "name": "Tyrosine-protein kinase-like otk", "aln": "---------MTARMISICGLVMA---------LMMASVLASSSRFQRVPQSQSVVENESVKFECESTDSYSELHYDWLHNGHRIAYDKRVHQIGSNLHIEAVRRTEDVGNYVCIATNLASGAREASPPAKLSVIYLESASVQLLGSN-------RNELLLKCHVEGASGDLEPLEIEWYRNSEKLSTWKN---VQLDQHRLIIRQPGSEDDGLYRCTASNAAGRVMSKQGYVYQSSVKCLPRLPRRKNEKMMESWDKQTFLCRGKRGGAAGLEALPAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKD-----GKLLRQVELGGSAPIPGHSFDSGKD--------------------ALLREDARLVLHKQNGTLSFASIIASDAGQYQCQLQLEAHAPINSSPGILEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENTTLPDHVEVDANGTLIFRNVNSEHRGNYTCLATNSQGQINATVAINVVVTPKFSVPPVGPIETSEQGTVVMHCQAIGDPKPTIQWDKDLKYLSENNTDRERFRFLENGTLEIRNVQVEDEGSYGCTIGN-SAGLKREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNDLSTKEAGGDQPDVAGNGKGSEQEPCLSKQHNG----------HSKSRSKSSGDAQKSDDTACSQQSRASKKSAHIYEQLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDADTEKQHSNSENGSGGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEQDQHNQSGLEQ-----LVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATKLPHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILLSCWVSNPKERPSFSQLGAALSKAMQSAEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :: * : *.**..::.. . :.** . . :* ** :* : :* . **.* : ** * :* * : *:* : :* . *. *.:.: ::*:..* * . :.:: *:**::* . :*:*:. ** :. *. ::.* :* ...*..*** * * .* *:. *.*.:. . : :.:.*: :: :: :: * *: . ...*: : : . * :* * : * : ::. *: .*: . : : * :* : * : :: ::::. * :..* **:* * *: * :. : * .:: :* ..:** :. . :.* :*.**.* * * *: : .:.** **** :..*: . * *:::.. *.*:* . ::*: . **: ** . : ..: *.* * ***::* : :.:. .: : ***.: .* :* *.* * .* . * * .***.* . . * * : :: * : . : :: : .: . *: :* . :.* :: :. .... . *. : : . * : .: * : : : :: :* : ..* .. .. : : * :. .*. .:.. :: . :: * * .: : : : * : .*::: *****:*: :*** :***:.::: :.* .****:***** :********.* ******* : .* :. .: **:*.* :*:. *:* **: : . **.*:***:***::*:: **** .*.** *. **::.*:: :*:**::**.: *.:::****::*:**::**:*.:. ::** :::*: ***. . . .*. *..* .:: **. .**:*****::.::*... .:: ", "identical_positions": 241, "similar_positions": 356, "identity": "21.87%" }, { "cls_id": "homologset.agr.FB:FBgn0004841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16610-1", "uniprot_id": "NK2R_RAT", "id": "P16610-1", "name": "Substance-K receptor", "aln": "-------------------------------------------------MG-TRAIVSDANILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEG-----ATKCVVAWPND--NGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTE-----EDRLELTHTPSLSRRVNRCHTKETLFMTGDMTHSEATNGQVGSPQDGE----PAGPICKAQA-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30549-1", "uniprot_id": "NK2R_MOUSE", "id": "P30549-1", "name": "Substance-K receptor", "aln": "-------------------------------------------------MG-AHASVTDTNILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGSTFCYFQNLFPVTAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAVIWLVALALASPQCFYSTITVDQG-----ATKCVVAWPND--NGGKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWGTPTE-----EDRLELTHTPSISRRVNRCHTKETLFMTGDMTHSEATNGQVGGPQDGE----PAGP-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21452-1", "uniprot_id": "NK2R_HUMAN", "id": "P21452-1", "name": "Substance-K receptor", "aln": "-------------------------------------------------MG-TCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQG-----ATKCVVAWPED--SGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTK-----EDKLELTPTTSLSTRVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QPL8-1", "uniprot_id": "F1QPL8_DANRE", "id": "F1QPL8-1", "name": "Substance-K receptor", "aln": "-------------------------------------------------MDTTLDPLSSSLLYYDEDGNETSINLFEQPDWQVALWAIAYTLIVIISFIGNVTVIWIILAHKRMRTVTNYFIVNLAFSDASMATFNTVFNFVYALHNDWYFGLGYCKFQNFFPITAMFSSIYSMAAIAVDRYMAIIHPLKPRLSSTTTKLLIGVIWTVAFSLAFPQCYYASTKFYFP-----RTVCMVEWPDD--YGGKHQLSYQIAVIILIYLLPLLVMLVTYSLVGQRLWGSEIPG-EASDHYQNQMQAKRKVVKMMIVVVTTFAICWLPYHIYFILGSFNRDIYKQHYIQQVYLAIFWLAMSSTMYNPIIYCCLNQRFRSGFRKAFQWCPFVKISE-----EDNMELQHMRTFHMRRSYRTETTSVVVRNHANEPEDTTSKLIKA-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30974-1", "uniprot_id": "TLR1_DROME", "id": "P30974-1", "name": "Tachykinin-like peptides receptor 86C", "aln": "MSEIVDTELLVNCTILAVRRFELNSIVNTTLLGSLNRTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIG-ENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRAETKSQWKRSTMETQIQQAPVTSSCREQRSAQQQQPPGSGTNRAAVECIMERPADGSSSPLCLSINNSIGERQRVKIKYISCDEDNNPVELSPKQM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: : :. * * ::** : :::::. ** *:**: .*. ********::**:::* *:::* .***:: :. * ** :* ::*:.. .:: *::::.**: ***:**:**:: * * ..: :: ** :: *: * *:: * *.: **:. . *:: :: * * :*: **: **::* ** : . . ::: :*.*: :: :* *********::** . .:.:: :::*::**.::*****.:* **:** :*:*** *: : * . :..: . * . : . . *.. ", "identical_positions": 98, "similar_positions": 123, "identity": "19.41%" }, { "cls_id": "homologset.agr.FB:FBgn0004852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26770-1", "uniprot_id": "ADCY4_RAT", "id": "P26770-1", "name": "Adenylate cyclase type 4", "aln": "----------------------------------------------------------MARLFSPRPPP------------------SEDLFYETYYSLSQQYP--------LLILLLVIVLCAIVALPAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQ--QLQRWTRPLSGLIWAALLALGYGFLFTGGVV---SAWDQVSFFLFIIFT-VYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWRPE--SQRDLLPQLAANAVLFLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQ----SSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVERADMEHRDPYLRELGEPTYLVIDPW---------------------------------------------------------AEEEDEKGTERGLLSSLEGHTMRPSLLMTRYLESWG----AAKPFAHLSHVD-----------------------------------------SPASTSTPLPEK---AFSPQWS---LDRS---------------------RTPRGL---------------------------------HDELDT-GDAKFFQVIEQLNSQK-QWKQSK------------------------------------DFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQMLVTTRPPALATTYSITFLLFLLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGLRVALGTATILLVFTMAVVSLLFLPV--------SSDCPFLAPNVSSVAFNTSWELP-----ASLPLISIPYSMHCCVLGFLSCSLFLHMSFELK-LLLLLLWLVASCSLFLHSHAWLSD-----------------------CLIARLYQGSLGSRPG--VLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMEN--------VLPAHVAPQLIGQ---------------NRRNEDLYHQSYECVCVLFASIPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATPGQDTQQDAERSCSHLGTMVEFAVALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGSPSAS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WF3-1", "uniprot_id": "ADCY4_MOUSE", "id": "Q91WF3-1", "name": "Adenylate cyclase type 4", "aln": "----------------------------------------------------------MARLFSPRPPP------------------SEDLFYETYYSLSQQYP--------LLILLLVIVLCALVALPAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQ--QLQRWTRPLSGLIWVALLALGYGFLFTGGVV---SAWDQVSFFLFIIFT-VYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWQPE--SQRALLPQLAANAVLFLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQ----RSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVERADTEHRDPYLRELGEPTYLVIDPR---------------------------------------------------------AEEEDEKGTAKGLLSSLEGHTMRPSLLMTRYLESWG----AAKPFAHLSHLD-----------------------------------------SPVSTSTPLPEK---AFSPQWS---LDRS---------------------RTPRGL---------------------------------DDELDT-GDAKFFQVIEQLNSQK-QWKQSK------------------------------------DFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQMLVTTRPPALIITYSITFLLFFLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGFRVALGTATILLVFTMAIASLLFLPV--------SSDCLFLASNVSSVTFNASWEMPGSLPLISIPLISIPYSMHCCVLGFLSCSLFLHMSFELK-LLLLLLWLVASCSLFLHSHAWLSD-----------------------CLIARLYQSPSDSRPG--VLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQ---------------NRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDSERSCSHLGTMVEFAVALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQSLGYTCYSRGSIKVKGKGELCTYFLNTDLTRTGSPSAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFM4-1", "uniprot_id": "ADCY4_HUMAN", "id": "Q8NFM4-1", "name": "Adenylate cyclase type 4", "aln": "----------------------------------------------------------MARLFSPRPPP------------------SEDLFYETYYSLSQQYP--------LLLLLLGIVLCALAALLAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQ--RLQRWTRPLSGLVWVALLALGHAFLFTGGVV---SAWDQVSYFLFVIFT-AYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPD--SRPALLPQLAANAVLFLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQ----GSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVEDAGMEHRDPYLRELGEPTYLVIDPR---------------------------------------------------------AEEEDEKGTAGGLLSSLEGLKMRPSLLMTRYLESWG----AAKPFAHLSHGD-----------------------------------------SPVSTSTPLPEKTLASFSTQWS---LDRS---------------------RTPRGL---------------------------------DDELDT-GDAKFFQVIEQLNSQK-QWKQSK------------------------------------DFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFIIQMLVTNRPPALAITYSITFLLFLLILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRPGLRIALGTATILLVFAMAITSLFFFPT--------SSDCPFQAPNVSSMISNLSWELPG-----SLPLISVPYSMHCCTLGFLSCSLFLHMSFELK-LLLLLLWLAASCSLFLHSHAWLSE-----------------------CLIVRLYLGPLDSRPG--VLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQ---------------NRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26769-1", "uniprot_id": "ADCY2_RAT", "id": "P26769-1", "name": "Adenylate cyclase type 2", "aln": "--------------------------------------------------------MRRRRYLRDRAEAAAAAAAGGGEGLQ----RSRDWLYESYYCMSQQHP--------LIVFLLLIVMGACLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIES--VFKKLLRVFSLVIWICLVAMGYLFMCFGGTV---SAWDQVSFFLFIIFV-VYTMLPFNMRDAIIASILTSSSHTIVLSVYLSATPG--AKEHLFWQILANVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPK----AGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPK---------------------------------------------------------GERRSPQHLFR-PRHTLDGAKMRASVRMTRYLESWG----AAKPFAHLHHRD-----------------------------------------SMTTENGKISTTDVPMGQHNFQ---NRTL---------------------RTKSQK---------------------------------KRFEEE-LNERMIQAIDGINAQK-QWLKSE------------------------------------DIQRISLLFYNKNIEKEYRATALPAFKYYVTCACLIFLCIFIVQILVLPKTSILGFSFGAAFLSLIFILFVCFAGQLLQCSKKASTSLMWLLKSSGIIANRPWPRISLTIVTTAIILTMAVFNMFFLSN--------SEETTLPTANTSNANVSVPDNQAS--ILHARNLFFLPYFIYSCILGLISCSVFLRVNYELK-MLIMMVALVGYNTILLHTHAHVLD-----------------------AYSQVLFQ-----RPG--IWKDLKTMGSVSLSIFFITLLVLGRQSEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLAR---------------SLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAIPSQEHAQEPERQYMHIGTMVEFAYALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNLAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TL1-1", "uniprot_id": "ADCY2_MOUSE", "id": "Q80TL1-1", "name": "Adenylate cyclase type 2", "aln": "--------------------------------------------------------MRRRRYLRDRAEAAAAAAAGGGEGLQ----RSRDWLYESYYCMSQQHP--------LIVFLLLIVMGACLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIES--VFKKLLRVFSLVIWICLVAMGYLFMCFGGTV---SAWDQVSFFLFIIFV-VYTMLPFNMRDAIIASVLTSSSHTIVLSVYLSATPG--AKEHLFWQILANVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPK----AGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPK---------------------------------------------------------GERRSPQHLFR-PRHTLDGAKMRASVRMTRYLESWG----AAKPFAHLHHRD-----------------------------------------SMTTENGKISTTDVPMGQHNFQ---NRTL---------------------RTKSQK---------------------------------KRFEEE-LNERMIQAIDGINAQK-QWLKSE------------------------------------DIQRISLFFYNKNIEKEYRATALPAFKYYVTCACLIFLCIFIVQILVLPKTSILGFSFGAAFLSLIFILFVCFAGQLLQCSKKASASLLWLLKSSGIIANRPWPRISLTIVTTAIILTMAVFNMFFLSN--------SEETTLPTANASNANVSVPDNQTA--ILHARNLFFLPYFIYSCILGLISCSVFLRVNYELK-MLIMMVALVGYNIILLHTHAHVLD-----------------------AYSQVLFQ-----RPG--IWKDLKTMGSVSLSIFFITLLVLGRQSEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLAR---------------SLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHAQEPERQYMHIGTMVEFAYALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNLAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08462-1", "uniprot_id": "ADCY2_HUMAN", "id": "Q08462-1", "name": "Adenylate cyclase type 2", "aln": "---------------------------------------------------MWQEAMRRRRYLRDRSEE----AAGGGDGLP----RSRDWLYESYYCMSQQHP--------LIVFLLLIVMGSCLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIES--VFKKLLRLFSLVIWICLVAMGYLFMCFGGTV---SPWDQVSFFLFIIFV-VYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSATPG--GKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPK----AGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPK---------------------------------------------------------GERRSPQHLFR-PRHTLDGAKMRASVRMTRYLESWG----AAKPFAHLHHRD-----------------------------------------SMTTENGKISTTDVPMGQHNFQ---NRTL---------------------RTKSQK---------------------------------KRFEEE-LNERMIQAIDGINAQK-QWLKSE------------------------------------DIQRISLLFYNKVLEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASPLLMWLLKSSGIIANRPWPRISLTIITTAIILMMAVFNMFFLSD--------SEETIPPTANTTNTSFSASNNQVA--ILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELK-MLIMMVALVGYNTILLHTHAHVLG-----------------------DYSQVLFE-----RPG--IWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLAR---------------SLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNVAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TBA8-1", "uniprot_id": "A0A8N7TBA8_DANRE", "id": "A0A8N7TBA8-1", "name": "adenylate cyclase", "aln": "MLRSTVEAILPVYRPCTTARESVVHLKDLCEEHDPHKPQPLYDREEHNTSSMWREAIRKRSYLLERSSKTGGNVKGGGGGVRGRRQRSPDWLYDSYHRMSQQHP--------LIVFLLLIVMGACLALLAVFFASGLDIEDHVAFVITVPTALAIFLTIFVLVCIES--VFKKLLRVFSLVIWGCLVAMGYLFMFFGGII---CPWDQVSFFLFIIFV-VYTMLPFSMRDAIIASVLTASSHTVVLSVCLSSTVS--HVEPLVWQILANVIIFICGNVAGAYHKHLMELALKQTYQDTCNCIKSPIKLEFEKRQQERLLLSLLPAHIARVMKAEIIQRLQGPK----FGQVENTNNFHNLYVQRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPESLPNHAKNCVKMGLDMCEAIKKVRDATGVEISMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITSETLEHLNGAYKVEDGHGQERDPYLKEHGVITYLVINPK---------------------------------------------------------VERKSPQHYYR-PRHTIDGAKMRASVRMTRYLESWG----AAKPFANLHHRD-----------------------------------------SMTNENGKINTADVPIGQYHFQ---RRSE---------------------RTKSQK---------------------------------KRFEEE-LNERMIRTFDGINSQK-QWLKSE------------------------------------DIQRISLFFHNKALEKEYRATTLPAFKYYITCACLIFFCIFIVQILVLPKTAILGVSFGMSFLILSVILLVCFIGHFLQCKKTASASWVWILRSSGIIASKPWPRITLTMATTALILIMAVFNMFFIED--------NLTLMETVYNTSNETLLQPDGQPI--PYLDKNTFYLPYFIYSCILGLISCSVFLRINYELK-MLIMLTAVVLYSVIILQTHASLLD-----------------------EYSKFLYKTEVIERPG--VLKDLKTMGSVSLFIFFITLLVLARQNEYYCRLDFLWKNKFKKECEEIETMENLNRVLLENVLPAHVAEHFLAR---------------NWKNEDLYHQSYDLVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATPGPEYTQEHDRQYMHIGTMVEFAFALVGKLDVINKHSFNDFKLRVGINHGPVKAGVIGAQKPQYDIWGNTVNVASRMDSTGVLGKIQVTEETSCILQTLGYTCSCRGIINVKGKGELKTYFVHTEMCRSLSQGNVMP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LQT1-1", "uniprot_id": "F1LQT1_RAT", "id": "F1LQT1-1", "name": "Adenylate cyclase type 7", "aln": "-------------------------------------------------------MPAKGRYFLNEGDEG----------------PKQAALYEKYRLTSQHGP--------LLLLLLLVAVATCIALVSIVFSH-EDLRRHQAVLGTAFFMLTLFVALYVLVYVEC--LAQRWLRVLALLTWACLMILGSVLMWDSLEN-EAYAWEQVPFFLFIVFV-VYVLLPLSTRAAIAVGVASTISHLLVFGAVTRAFKTSMSSTQLGLQLLANAVILLGGNFTGAFHKHQLQDASRDLFIYTVKCIQIRRKLRVEKRQQENLLLSVLPAHISMGMKLAIIERLKEGG----DRHYTPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLNHLDKAYEVEDGHGEQRDPYLKEMNIRTYLVIDPR---------------------------------------------------------SQQPPLPSHHLSKPKGDATLKMRASVRVTRYLESWG----AARPFAHLNHRE-----------------------------------------SVSSSEIPIPNGRRQKAIPLR--RHRAPD---------------------RSASPK---------------------------------GRLEDD-CDDEMLSAIEGLSSTRPCCSKSD------------------------------------DFHTFGPIFLEKGFEREYRLVPIPRARYDFACASLVFVCILLVHLLVMPRMATLGLSFGLVACLLGLVLSFCFATEFSRCLPARST----LQAISESVETQPLLRLSLVVVTVGSLLTVAIINMPLTFN--------PGPEQPGDNETSPLAARNR---------VGTPCELLPYYTCSCVLGFIACSVFLRMSLELK-AMLLTVALVAYLLLFNLSPCWQVSGNSTETNSTHRTRRLLSAEQSMNSHTLALGAQMTAPSPSSCLERDLKTMINFYLVLFYATLILLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIG----------------DKAAEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGHEN-QDLERKHVHIGVLVEFSMALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51829-1", "uniprot_id": "ADCY7_MOUSE", "id": "P51829-1", "name": "Adenylate cyclase type 7", "aln": "-------------------------------------------------------MPAKGRYFLNEGDEG----------------PDQAALYEKYRLTSLHGP--------LLLLLLLVAAATCIALISIAFSH-EDLRRHQVVLGTAFLMLTLFVALYVLVYVEC--LVQRWLRALALLTWACLMVLGSVLMWDSLEN-EAHAWEQVPFFLFVVFV-VYALLPLSRRAAIVAGVTSTVSHLLVFGAVTRAFQTSMSSTQLGLQLLANAVILLGGNFTGAFHKHQLQDASRDLFIYTVKCIQIRRKLRVEKRQQENLLLSVLPAHISMGMKLAIIERLKEGG----DRHYMPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLNHLDKAYEVEDGHGEQRDPYLKEMNIRTYLVIDPR---------------------------------------------------------SQQPPPPSHHLSKPKGDATLKMRASVRVTRYLESWG----AARPFAHLNHRE-----------------------------------------SVSSSETPISNGRRQKAIPLR--RHRAPD---------------------RSASPK---------------------------------GRLEDD-CDDEMLSAIEGLSSTRPCCSKSD------------------------------------DFHTFGPIFLEKGFEREYRLVPIPRARYDFACASLVFVCILLVHLLVMPRMATLGVSFGLVACLLGLVLSFCFATEFSRCFPSRST----LQAISESVETQPLVRLVLVVLTVGSLLTVAIINMPLTLN--------PGPEQPGDNKTSPLAAQNR---------VGTPCELLPYYTCSCILGFIACSVFLRMSLELK-AMLLTVALVAYLLLFNLSPCWHVSGNSTETNGTQRTRLLLSDAQSMPSHTLAPGARETAPSPS-YLERDLKIMVNFYLILFYATLILLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIG----------------DKAAEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSAPSGHEN-QDLERKHVHIGVLVEFSMALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51828-1", "uniprot_id": "ADCY7_HUMAN", "id": "P51828-1", "name": "Adenylate cyclase type 7", "aln": "-------------------------------------------------------MPAKGRYFLNEGEEG----------------PDQDALYEKYQLTSQHGP--------LLLTLLLVAATACVALIIIAFSQ-GDPSRHQAILGMAFLVLAVFAALSVLMYVEC--LLRRWLRALALLTWACLVALGYVLVFDAWTK-AACAWEQVPFFLFIVFV-VYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTT--PSVRVGLQLLANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGMKLAIIERLKEHG----DRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQVREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPR---------------------------------------------------------SQQPPPPSQHLPRPKGDAALKMRASVRMTRYLESWG----AARPFAHLNHRE-----------------------------------------SVSSGETHVPNGRRPKSVPQR--HRRTPD---------------------RSMSPK---------------------------------GRSEDDSYDDEMLSAIEGLSSTRPCCSKSD------------------------------------DFYTFGSIFLEKGFEREYRLAPIPRARHDFACASLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGT----LCTISERVETQPLLRLTLAVLTIGSLLTVAIINLPLMPF--------QVPELPVGNETGLLAASSK---------TRALCEPLPYYTCSCVLGFIACSVFLRMSLEPK-VVLLTVALVAYLVLFNLSPCWQWD----------------CCGQGLGNLTKPNGTTSGTPSCS---WKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIG----------------DKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHEN-QELERQHAHIGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QC34-1", "uniprot_id": "A0A8M9QC34_DANRE", "id": "A0A8M9QC34-1", "name": "adenylate cyclase", "aln": "-------------------------------------------------------MPAKGKYSLDKQE------------------LKQEALYRKFSGISQYRQ--------FVLLLGLSIVTCATLLVLFFSFK-LKAQNHGIFVGVVGGALCLFLAVFVLVCTET--LSQRWRTLLGLGVWATHLTMGFTFIFSTKSDLQIQPWDQVPFFLFIIIT-VYTMLPFQMSYAVILSIISSLSHIIVLSVYLTVAQL--HSNPITFQLLSNAVVFGCGIMVGIFHKVLMEKALKQTFQDTLRCLGIRMKLEIEKRQQENLLQSVLPVYISMKMKLAIMERCKCKDKEE-QQRMVRDNNFHSLYVKRHENVSILYADIVGFTRLASDCSPKELVLMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPVSLPNHAKNCVKMGLDMCEAIKQVREATGVDINMRVGVHSGNVLCGVIGLRKWQFDVWSHDVTLANHMESGGLPGRVHITEATLKHLNKAYEVEEGNGHLRDTYLKELNIKTFLVIDPR---------------------------------------------------------SKDSSLMAPSITKPRVSDGLKMRASVRMTRFLESWG----AVKPFAHLQSRE-----------------------------------------EFNTDAMVNGKG-HCKDIPLRSVPTHNPDSFDESLEEPFSLPAPPLSTYNRNKSQK---------------------------------TKFDEE-LHDKMTTTINDLSSSK-QWVKSE------------------------------------EISGLTLWFTKKDLEMQYRTIEMPNFKYYIGCATFIFICIFIIQMLVTKQRIELGLGFAVLACFLLLILCICFADHIQRMFPEKLKSCTWLLALSKAVVKRPFVRILLATVATTVIVVIAMFELFLKKT--------DNLCDLLQQNS---SFADS---------ARDELQYLPYLVYNCILALIACGVFLRVSFELKLAFLLIVSLVSYTIILYSQENLFSN------------------YNCLLYTNHSCGDSLMVCKAG--LMKHPKIMSCIYITLFLFTMLLISRQNEYCCRQDFLLKNKNLADKEEVELCENLNRLLLENVLPAHVAALFVGENKKNEVGLLSAISLLNRKYKDLYYKSYDCVCVMFASVPDFKEFYTECDINKEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAAAGLSGPPEQSN-QDRERQNAQIGNMVEFAIALIGKLDGINRHSFNTFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETSIVLQNLGYSCECRGLINVKGKGELKTFFVCTDSSKQQGIGLS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW60-1", "uniprot_id": "ADCY2_DROME", "id": "Q9VW60-1", "name": "Adenylate cyclase type 2", "aln": "-----------------------------------------MVNHNAETAKTGNGTNATANLIVKADGNATQPKAMTSSAAR-----MNDALSASLADLSEQENGTTAEDIHLNDLYTRYRQRLRKSLFRSGLLTSLLACVVSIIIGIVYGQHLVQTMLLVLAALISGSILTALQFPAVLSSPAAALAFAIVTTFSLGTIAAITGDELAPLPMYALFLCIHSMLPISWPVSVVLALFMTAIHIVYR---IGTSPD---YAPNLPMLFGEIVMLASASVSGLYYRIMSDAAHNRTVDGTRTGIEQRVKLECEREQQEQLLLSVIPAYIAAEVKRSIMLKMADACQRAGGQASTSATRFHELHVQRHTNVTILFADIVNFTPLSSSLTASDLVKTLNDLFGRFDQIAQENQCLRIKILGDCYYCVSGLPISRPQHATNCVNMGLQMIDAIRHVREATGINVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGRVHITKQTLDFLGDKFEVEQGEGGNRDAYLADHKVESYLIVPPKPAYTYSVPRVVECIEQNDPSPTTEETKEIKETDQSHEATDVADVLLPVTVAPPPAIVDEKMSPTSINSQEAPLHAPLASAASMSIKELSEEEDEADEATAVTEPLMHRDQDGKNDKEPKANGGHRGSGDSAASESVAKSAALSLPADDLLSMSGSESGISNSGAQAQSSNPASVTPTAAAPAGGAASNSLTVAEAPERSRRKLSVQGLMSFADRRRSSGAFIEGRKLSIHSGESFRSHAGHVTRNRPSSKMTKYVECWGADRPFANIAESKLVKNIGLASIAMIESNLLPPERKCFNFNFFGPPTELKPFTMWYRNTPREAMYRAQPDTHFRFDLICAFVLFLSLAVVQLIVIELNLALLGSLLASFVSLALFLYLSNMSVPDVHASTTER-----NGPGQVVASSRYLRLAMFVVVNILISSCAVFSVINYTVPDGVSKEPSSNQTILESNFSSVFVNSTLEDVQ-LWEIDYAIPIAPVFLYCCAISLAAISAFLRSGFILK-LIAMLVAVIAQVTVLGYSDLFEMYN----------------------DANITHG-------------LPLEIKGFLLLLVIILVLHTLDRQGEYVARTDFLWKAKLKVEQEEVETMRGINKILLENILPAHVATHFLHL----------------ERSTELYHESYSCVAVMFASIPNYKEFYDETDVNKQGLECLRLLNEIICDFDKLLLKPKFSGIEKIKTIASTYMCASGLRPGKEDGATDEKRTEEHNVVILVEFAIALMSILDSINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGVMGRLQTTENTAKILMTAGYECECRGLTYVKGKGNLVTYFVKTPFDGKL-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : * .: . : * : :. : .. :: :: : :**: : . : * : : .: ::: . . * ::: : * . : : :* *:.:**.** *::*.::: :* *: : ..**.*:*:** .*::*:****.** *:*. :. :** **:***:*****: ::*:**************** * * ** ***.***:: **:::* ***:::.**:*:*:*.*****:**:***:****.**:***:**:.*:.*****: ** * : ** . **.** : ::::: * : .*: :.. *. . *. * : . *. .: .: .: : :. :: : : :. * ** . :. *: .:*.. ::::: * : ..* .. . : . *: : . : *: .: : * * :.: : . **: . * . : : :: : . : :: .: : ** :* .* * * * * : ** * .. :****** :: : *::**. *.*:***:*::* ** * ::*::************.***.** ******:******.****.*:** :: . :: :***: ** . *. **:.**: *:**:*:***** ******:*******.*********:* * :.::*.**:*. * ** * .** *****:* *:*: * ", "identical_positions": 269, "similar_positions": 240, "identity": "18.89%" }, { "cls_id": "homologset.agr.FB:FBgn0004854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63156-1", "uniprot_id": "BARH1_RAT", "id": "P63156-1", "name": "BarH-like 1 homeobox protein", "aln": "---------------------------------MEGSNG--FGIDSILS-HRAGSPA--LPK------GDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETS-------------------------------------------------------------------------------TSRPGAASGPGLDSHLQPG--------------------------------------------QL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAG--------EDFRDKLDK------------------SVSSASSDSEYKVKEEGDREIS--------SSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP--SPYFYPQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVPRILIHG-----------------------------------LQGASEPPPPLPPLPGVLPRAAQPR-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63157-1", "uniprot_id": "BARH1_MOUSE", "id": "P63157-1", "name": "BarH-like 1 homeobox protein", "aln": "---------------------------------MEGSNG--FGIDSILS-HRAGSPA--LPK------GDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETS-------------------------------------------------------------------------------TSRPGAASGPGLDSHLQPG--------------------------------------------QL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAG--------EDFRDKLDK------------------SVSSASSDSEYKVKEEGDREIS--------SSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP--SPYFYPQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVPRILIHG-----------------------------------LQGASEPPPPLPPLPGVLPRAAQPR-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE3-1", "uniprot_id": "BARH1_HUMAN", "id": "Q9BZE3-1", "name": "BarH-like 1 homeobox protein", "aln": "---------------------------------MEGSNG--FGIDSILS-HRAGSPA--LPK------GDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETG-------------------------------------------------------------------------------TPRPGGASGPGLDSHLQPG--------------------------------------------QL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAA--------EDFRDKLDK------------------SGSNASSDSEYKVKEEGDREIS--------SSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP--SPYFYPQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVPRILIHG-----------------------------------LQGASEPPPPLPPLAGVLPRAAQPR-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88181-1", "uniprot_id": "BARH2_RAT", "id": "O88181-1", "name": "BarH-like 2 homeobox protein", "aln": "------------------------------MTAMEGASGSSFGIDTILSGAGSGSPG--MMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHGQQ-----------------------------------------------------------PPPPSAPPAQSLQPSPQQQ---PPPQPQS-------------------------------AAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQECNAAHESFRPKLEQEDSKTKLDK------------------REDSQSDIKCHGTKEEGDREIT--------SSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP--SPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHG-----------------------------------LGPGGQP--ALNPLSNPIPGTPHPR-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIB5-1", "uniprot_id": "BARH2_MOUSE", "id": "Q8VIB5-1", "name": "BarH-like 2 homeobox protein", "aln": "------------------------------MTAMEGASGSSFGIDTILSGAGSGSPG--MMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHSQQ-----------------------------------------------------------PPPPSAVPAQSLQPSPQQQ---PPPQPQS-------------------------------AAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDGKTKLDK------------------REDPQSDIKCHGTKEEGDREIT--------SSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP--SPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHG-----------------------------------LGPGGQP--ALNPLSNPIPGTPHPR-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY43-1", "uniprot_id": "BARH2_HUMAN", "id": "Q9NY43-1", "name": "BarH-like 2 homeobox protein", "aln": "-------------------------------MTMEGASGSSFGIDTILSSASSGSPG--MMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQ-----------------------------------------------------------PPPPAAAPTQSLQPLPQQQQPLPPQQPPPP------------------------------PPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDK------------------REDSQSDIKCHGTKEEGDREIT--------SSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP--SPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHG-----------------------------------LGPGGQP--ALNPLSSPIPGTPHPR-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24256-1", "uniprot_id": "BARH2_DROME", "id": "Q24256-1", "name": "Homeobox protein B-H2", "aln": "MTTMPPEMSATTAAPVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTATRSRFMITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPGAAPMLSGYYAAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIERERERERERDEDDEEELALEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . .* :: : :.: . : . . . : :. *. . :.. * : . .. . : * . . *.:::::: .: *:* . * .: . .: . .. . .::** .:. ** . . ** *******:**** **:**************:** *:*:* ******************************:*:**:: :**: . . . .: ** ..*. . : .* . :: ..: * .. * :.:. ", "identical_positions": 88, "similar_positions": 92, "identity": "13.64%" }, { "cls_id": "homologset.agr.FB:FBgn0004855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36954-1", "uniprot_id": "RPB9_HUMAN", "id": "P36954-1", "name": "DNA-directed RNA polymerase II subunit RPB9", "aln": "ME---PDG-TYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAE-DAMRLYYVCTAPHCGHRWTE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60898-1", "uniprot_id": "RPB9_MOUSE", "id": "P60898-1", "name": "DNA-directed RNA polymerase II subunit RPB9", "aln": "ME---PDG-TYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAE-DAMRLYYVCTAPHCGHRWTE----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RCG9-1", "uniprot_id": "M0RCG9_RAT", "id": "M0RCG9-1", "name": "", "aln": "ME---PDG-TYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEPDDLSIYRMDKVPQRSPSWPGTQTCAFL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1LVK2-1", "uniprot_id": "Q1LVK2_DANRE", "id": "Q1LVK2-1", "name": "DNA-directed RNA polymerase subunit", "aln": "MD---LEGGNYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVAQDPTLPRTEDHPCPKCGHKEAVFFQSHSMKAE-DAMRLYYVCTAPHCGHRWTE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36958-1", "uniprot_id": "RPB9_DROME", "id": "P36958-1", "name": "DNA-directed RNA polymerase II subunit RPB9", "aln": "MTTAFDAAHTEGPGFVGIRFCQECNNMLYPKEDKENKILLYACRNCDYKQEADSNCIYVNKIMHEIDELTHIVPDVISDPTLPRTEDHACPKCSHREAVFFQAQTRRAE-EEMRLYYVCTNQNCTHRWTE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27999-1", "uniprot_id": "RPB9_YEAST", "id": "P27999-1", "name": "DNA-directed RNA polymerase II subunit RPB9", "aln": "--------------MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPR-SDRECPKCHSRENVFFQSQQRRKD-TSMVLFFVCLS--CSHIFTSDQKNKRTQFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :***::*******:*****. **: **.*.* :**.. :* ::: ::.* : :: *: .****** .*: * ** :* ****:: : : : :: : :. ", "identical_positions": 41, "similar_positions": 38, "identity": "29.29%" }, { "cls_id": "homologset.agr.FB:FBgn0004856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CSN1-1", "uniprot_id": "SNW1_MOUSE", "id": "Q9CSN1-1", "name": "SNW domain-containing protein 1", "aln": "----------------------------------------------------------MALTSFLPAPTQLSQDQLEAEERARSQRSLQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRK---KKMSNALAIQVDPEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKEPMEP--PRFKINKKIPRGPPSPPAPVMHSP-SRKMTVKEQQEWKIPPCISNWKNAKGYTIPIDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKE-------DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSN-EVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRKQRG--REGPVQFE--EDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8G7-1", "uniprot_id": "D4A8G7_RAT", "id": "D4A8G7-1", "name": "SNW domain-containing protein 1", "aln": "MVPVPTRQAATIPTKRTTRPRVPFGQSACAVSIFHSVPRSRARIAPRRCGLRRKKRKKMALTSFLPAPTQLSQDQLEAEERARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRK---KKMSNALAIQVDPEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEP--PRFKINKKIPRGPPSPPAPVMHSP-SRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKE-------DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSN-EVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLETRIKTNRFVPDKEFSGSDGRKRG--REGPVQFE--EDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13573-1", "uniprot_id": "SNW1_HUMAN", "id": "Q13573-1", "name": "SNW domain-containing protein 1", "aln": "----------------------------------------------------------MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRK---KKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEP--PRFKINKKIPRGPPSPPAPVMHSP-SRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKE-------DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSN-EVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRG--REGPVQFE--EDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39736-1", "uniprot_id": "BX42_DROME", "id": "P39736-1", "name": "Puff-specific protein Bx42", "aln": "----------------------------------------------------------MSLSSLLPTPTNAIWDREDERRLVARGAPKIGALVSAKIAAPPYGQRKDWVPHTDADFGDGGAFPEIHVAQYPLGLGAPGNVGKKSDALAVRLDDKGKVKYDAIARQGHGKDKIVYSSISQLLPAEVLAEDADELQRPDEETVMETTEETRLALEKLTNQKITSALPVRHAQKAGPAQYIRYTPSQQGDTFNSGAKQRVIRMVEAQLDPMEP--PKFRINKKIPRGPPSPPAPVLHSP-SRKVTVKEQKEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQQVHINEKFAKMAEALYIADRKAREAVEARSQLEKKLAQKEKEKKEDMLRMMAQRAREERAGLRNPEAAEPSGSGATGSEVRERNDLRAERQRERQRDRNLQRAAPEKRSKLQKERERDISEQIALGLPAKSAGNGETLFDQRLFNTTKGMDSGYG--DDEAYNVYDKPWRDSNTLGAHIYRPSKQADSDNYGGDLDAIVNTKRFVPDKQFSGASKEAAAGQRSGPVEFEKEEDPFGLDQFLNMAKKAP--KRAEEKNNERSSHSDRKRSKRD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28004-1", "uniprot_id": "PRP45_YEAST", "id": "P28004-1", "name": "Pre-mRNA-processing protein 45", "aln": "-----------------------------------------------------------MFSNRLPPPKHS-------------QGRVSTALSSDRVEP--------------------------------------------------------AILTDQIAKN---------VKLDDFIPKRQSNFELS-VPLPTKAEIQECTARTKSYIQRLVNAKLANSN------NRASSRYVTETHQAPANLLLN--NSHHIEVVSKQMDPLLPRFVGKKARKVVAPTENDEVVPVLHMDGSNDRGEADPNEWKIPAAVSNWKNPNGYTVALERRVGK-ALDNENNTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQEMLAKESKLKELSQRARYHNGTPQTGAIVK----------------------------PKKQTSTVARLKELAYSQGRDVSEKIILGAAKRSEQP-DLQYDSRFFTR--GANASAKRHEDQVYDN-----------------------PLFVQQDIESIYKTNYEKLDEAVNVKSEGASG--SHGPIQFT----------------------KAESDDKSDNYGA--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. **.*.: :* * : . : * **:: . :::* . : : * : : * * .*: ::: .. *:: : : ..::*: * . . : . :.: *.:*. * :*: * : .* :. . .**:* *.. : :*****..:*****.:***:.:::*:. . . : **: * *::*** **:***: :. : :::: ::* :*. *: ::*:** ... :. : : . :: : .:* .. **:** * ** . : :*.*:*. * ::. :*: *: *::: :*: *: .. . . **::* :...... . ", "identical_positions": 78, "similar_positions": 143, "identity": "12.75%" }, { "cls_id": "homologset.agr.FB:FBgn0004858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABF5-1", "uniprot_id": "D4ABF5_RAT", "id": "D4ABF5-1", "name": "", "aln": "MSDSPAG--SNPRTPESSGSGGS----GGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAAS---AAAALKQLGDS---PAED-KSSFKPYSKGSGGGDSRKDGGSSSVSSTT------SSSSSSPGDKAG-FRVPSAACPPFPPHGAAVSTSSNSSSPGGSRGGSPHHSDCKSGSGGAGGGGELDKKDQEAKPSPEPAAGSRGSSGDS-AHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPAGPSLKASGYPLVYPG---HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGP-CDKRFATSEELLSHLRTHTALPGAE-KLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRSPHTLGLSRYHPYGKS-----HLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CL69-1", "uniprot_id": "ZN703_MOUSE", "id": "P0CL69-1", "name": "Zinc finger protein 703", "aln": "MSDSPAG--SNPRTPESSGSGGGSSSGGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAAS---AAAALKQLGDS---PAED-KSSFKPYSKGSGGGDSRKDSGSSSVSSTT------SSSSSSPGDKAG-FRVPSAACPPFPPHGASVSTSSNSSSPGGSRGGSPHHSDCKNGGGGAG---ELDKKEQEAKPSPEPAAGSRGSGGDS-AHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPTGPSLKASGYPLVYPG---HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGP-CDKRFATSEELLSHLRTHTALPGAE-KLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRSPHTLGLSRYHPYGKS-----HLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7S9-1", "uniprot_id": "ZN703_HUMAN", "id": "Q9H7S9-1", "name": "Zinc finger protein 703", "aln": "MSDSPAG--SNPRTPESSGSGSG-----GGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAN-GLGAEKDPGRSAPGAAS---AAAALKQLGDS---PAED-KSSFKPYSKGSGGGDSRKDSGSSSVSSTS------SSSSSSPGDKAG-FRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGG--GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPG---HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGP-CDKRFATSEELLSHLRTHTALPGAE-KLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRNPHTLGLSRYHPYGKS-----HLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90ZE2-1", "uniprot_id": "ZN703_DANRE", "id": "Q90ZE2-1", "name": "Zinc finger protein 703", "aln": "MSELPPGFAVSPRNQQTFKSHYITNDSSPTCLGLQVDSIAS-LPYRDPARQEKRLPIRILKMLTAHTSHILHPEYLQPLSSAPVS-IELDAKKSPLALLAQTCSQIGKPDPPPSSKLGSLSSSSHGDKDSRSSSSSLKSGEHQNLDDKSSFKPYSKT---GSECRKEGAGINSSADKAGFRVPNGSSSSVTCTSLPPHAPSPRASSPQQTSGQSHTHRQSQSPLSQKTAHLQTTHMDSKAAGSDPGNDSSSSGSDRNGKKD--SDHNKSSLDVVQIANSSHARASVNSSSASSSSSPQPDSKTDSQPPQPSLGTGHIAPVSPFKPGHSVFPLPSSTMGYHGSIVGAYTGYPSQFVPGLDPAKS-------SLGMGVP-GKHPSSSPLTGASPPSFMQGLCRDPYCLT-YPNAPHLGGSNCSSC-VHDPS--SALKSGFPLMYPTHHLHSLHPSSLSSSATSSLS--HPLYTYGFMLPNETLPHACNWVSVGGP-CDKRFATSEELLAHLRTHTALPGVDGKLLSGYP---------SSVSSAASCHLHLPPPSSPGALPSSLSLRGSPGLGLARYHPYGKA-----HLPGAPSLPMHSLPATAPYYSPYALYSQRLGSASALGYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJS8-3", "uniprot_id": "ELBOW_DROME", "id": "Q9VJS8-3", "name": "Zinc finger protein Elbow", "aln": "--------MLQSSNHHYLRPDYMTAAAAPTAQLDNKSSPLALLAQTCSAIGADTTNPKLLAANIEKSTKQLQHHPKGSSGSGGSGSFGLSQQAS----MDGSARDKSSPVSSHSSSVSTGSVEQQQLPPAHGSSSSSKP-------TPTTFKPYEPNNNIS------NITTAADCGATNLSSNNTSAQQRVKTP------KSMTNGGGQRCDSNQSASSQHRESPTAAGSLRRTPTSGLAGGVMQHNGSPGLPPTASTTPG---RSNSKESAAMHSPSAAAAAAAAAAQIASSNRLQEAALAAAKEAN-------YVKALHAASQQGSASAAAAAASYYPPGYGSPYSMDLMTASSLMSPHHAMFKASAMNPYLNYARMKGLTEQSMMAATP-----NVCRDPYCTGCPASPHYINKAAGQPCPAGCPQCEGGGGGGGGSSKSSGSQGGSGGSSSAAAAAAAAAASSYHAQLAALAAASQMPYVCSWIGSDAAYCGKRFGTSDDLFQHLRTHTAS--------------------VPDAVLSAAAAGGIPP--NHPLFQRTYPTPPLSPLSAARYHPYGKPSMLPPSLAPPGMPGLPPHPALAQYFAPYSLYGPRMGSSHP----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . : : *. . . ::* :: : *: . . .* . : *. : * : :. : ..* .. **.:.: : :. ... . :::* . . :. . . : .:.. *. .. :.. : .. : . . : : .. ..* . . . . :... ...: . .. : . .:. :: .: . . *. . ..:: * . ..*: . :.* :: . :. . * :...: .*:* .:****** .. ::. : ..* . * . .* . :: :::*: : . : . :*: *.*:. ... *.***.**::*: ******* . . :*:. :** : . *. :*******. *. . : . *: . *::**:**. *:.*: . ", "identical_positions": 66, "similar_positions": 188, "identity": "10.56%" }, { "cls_id": "homologset.agr.FB:FBgn0004859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2B7-1", "uniprot_id": "F1M2B7_RAT", "id": "F1M2B7-1", "name": "", "aln": "METSAQ-APALEKKEAKSGLLEDSSFPDPGKKACPLAVAAPAA-------------AVAAQG------------------------------------------------------------VPQQLLPSFHVPLPIDMRHQEGRYHYDPHPVHGVHGPPTLSGSPVISDISLIRLSPH--PAGPGESPFSAHHPYMNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFSLAAPGTNPSDYYHQMTLMASHPTPYGDILMQSGGAASAPHLHDYLNPVDASRFSSP---RVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALS---------------------------------PAFTFPHPINPV---AYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMTLTSIT-VPTQLGSNSSNCISDANQNKQNSESAVSSTVNPITIHKRSKVKTEAEGLRPASPLGLTQ-----------------EQLADLKEDLDRDDCKQEAEVVIYETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRAPLLKENGDNEAGAEPGGRGP---EESVEASSTSHTAEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSVPNNDSGVEMPGTGPGSLGDLTALDDTSPGADTSALAVPSTGGLQLRKHMTTMHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPVNGSVLENFNNTGGCGPAGLLPNQRLPEL--TEVTMLSQLQERRDSSTSTMSSAYTVSRRSSGISPYFSSRRSSEASPLGGIRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYSLRAKYAAATG-GPPPTPLPGLDRVSLRTRLALLDAPERALPGACPQPLGPRRGSDGPTYNHGHG--YVGAAPALPHEGPNGSTRRASDPVRR-PDPLVLPRVQRFHSIHNMNPGPLPPCTDRRGLHLQSHPSVDGSLTR-HAYSPRPPSINENVVMEAVAAGVEGAGLESDLGLVEDDLVLPDDVVQYIKAHTGGALDDSTRQVYPTEGTGFPENSKLPS-PGLQGHRRLAAADSNMSPSAPGLGGCQLSYSPSSSLNKSNMPVQWNEVSSGTVDALPTQVKPPSFPQSN--LVQQKPAFAHYPGYSPQALQSGSGGLDSTQPHLQLR-GAPS--ASRGSYTQQPRLPATGSQCLGVTAAMSPQANYSQTHHQLSPNVVSGSLNQFAPSCSNMAAKPSHLG--LPQQMEVVPN---ATIISGHQRELGIASSSLAAVSQPHPVLGYPQQ----------DGYQQVSGLPSSHQPSFMESQQ------NTGFGLMQPRPPLEPNTASRHRGVRSGQQQQQLYARTAGQAVVTS-ANQETAEAMPKGTAGTVVSLTPQPS-QDTGRSQDQNTLYYYGQIHMYEQNGG------CPAMQPQPPQPQGCSDNIQPEPLPSPGVNQVSSTVD---SQLLEPPQIDFDAIMDDGDHSSLFSGALSPSLLHNLSQNSSRLTTPRNSLTLPSIPVGISNMAVGDMSSMLTSLAEENKFLNMMT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VGT2-1", "uniprot_id": "GLI2_MOUSE", "id": "Q0VGT2-1", "name": "Transcription activator GLI2", "aln": "METSAP-APALEKKEAKSGLLEDSSFPDPGKKACPLAVAA----------------AVAAHG------------------------------------------------------------VPQQLLPAFHAPLPIDMRHQEGRYHYDPHSVHSVHGPPTLSGSPVISDISLIRLSPH--PAGPGESPFSAHHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFSLAAPGTNPSDYYHQMTLMASHPTPYGDLLMQSGGAASAPHLHDYLNPVDASRFSSP---RVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALS---------------------------------PAFTFPHPINPV---AYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMTLTSISTMPTQLSSSSSNCLNDANQNKQNSESAVSSTVNPITIHKRSKVKTEAEGLRPASPLGLTQ-----------------EQLADLKEDLDRDDCKQEAEVVIYETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHVRAPLLKENGDNEASAEPGGRGP---EESVEASSTSHTVEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGMEMPGTGPGSLGDLTALADTCPGADTSALAAPSTGGLQLRKHMSTVHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPVNGSVLENFNNTGGGGPAGLLPSQRLPEL--TEVTMLSQLQERRDSSTSTMSSAYTVSRRSSGISPYFSSRRSSEASPLGGLRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYNLRAKYAAATG-GPPPTPLPGLDRVSLRTRLALLDAPERALPGACPHPLGPRRGSDGPTYSHGHGHGYAGAAPAFPHEGPNSSTRRASDPVRR-PDPLILPRVQRFHSTHNMNPGSLPPCADRRGLHVQSHPSVDSNLTR-NAYSPRPPSINENVVMEAVAAGVDGPGLECDLGLVEDELVLPDDVVQYIKAHTGGTLDDGIRQGYPTEGTGFPENSKLPS-PGLQGHRRLAAADSNMGPSAPGLGGCQLSYSPSSNLNKSNMPVQWNEVSSGTVDALPTQVKPPPFPHSNLAVVQQKPAFGQYPGYNPQSVQSSSGGLDSTQPHLQLR-GAPS--ASRGSYTQQPRQPAAGSQCLGMSAAMSPQASYSQAHPQLSPNIVSGSLNQFSPSCSNMAAKPSHLG--LPQQMEVVPN---ATIMNGHQREHGVPNSSLAAVSQPHPVLSYPQQ----------DSYQQGSNLLSSHQPGFMESQQ------NAGFGLMQPRPPLEPNTASRHRGVRSGQQQ--LYARTTGQAMVTS-ANQETAEAMPKGPAGTMVSLAPQPS-QDTGRAQDQNTLYYYGQIHMYEQNGG------CPAVQPQPPQPQACSDSIQPEPLPSPGVNQVSSTVD---SQLLEPPQIDFDAIMDDGDHSSLFSGALSPTLLHNLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10070-5", "uniprot_id": "GLI2_HUMAN", "id": "P10070-5", "name": "Transcription activator GLI2", "aln": "METSAS-ATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAA------------AVAAQG------------------------------------------------------------VPQHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPH--PAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSP---RVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALS---------------------------------PAFTFPHPINPV---AYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSS-SSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGG------PESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGG-SGLLNLTPAQQYSLRAKYAAATG-GPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHA----GAAPAFPHEAPGGGARRASDPVRR-PDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLAR-GAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPS-PGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLG--HPQQTEVAPD---PTTMGNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQ-LAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVD---SQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M9H1-1", "uniprot_id": "F1M9H1_RAT", "id": "F1M9H1-1", "name": "", "aln": "MEAQSHSSTTTERKKAESSIAKCPTRTDVSEKAVASSTTSNEDESAGQIYHRERRNAITMQPQSVQGLSKISEEPSTSSDERASLIKKEIHGSLPHLAEPSLPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHVPSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMD-YIRSLHSSPSLSMISAARGLSPTDAPHA-------------GVSPAEYYHQMALLTGQRSPYADILPSAATAGAGAIHMEYLHAMDSTRFPSP---RLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAIS---------------------------------PALSFTYPSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSS----GPSESSQSKPTSESAVSSTGDPMHN-KRSKIKPDEDLPSPGSRGQQEQ----------------PEGTTLVKEEGDKDESKQEPE-VIYETNCHWEGCTREFDTQDQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDMHPRPPPPRDSGSHSQSRSPGRPTQGAFGEQKELSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSIADLSAIDET-PIMDSTISTATTALALQGRRNPAGTKWMEHIKLERLKQVNGMFPRLNPILPSKAPAVSPLIGNGTQSNNNYSSGG--PGTLLPSR--SDLSGVDFTVLNTLN-RRDSNTSTISSAYLSSRRSSGISPCFSSRRSSEASQAEG-RPQNVSVADSYDPISTDASRRSSEASQ-GDGLPSLLSLTPVQQYRLKAKYAAATG-GPPPTPLPHMEKLSLKTRMALLGE-GRDSGVTLPPVHPPRRCSDGGGHTYSRR-------HLLPHDALANSARRASDPVRTVSENMSLPRVQRFSSLNSFNPPNLPPSVEKRSLVLQNYTRQESTHPRYFQASPCPPSITENVALEALTMDADAS--------LNDEDFLPDDVVQYLNSQNQTGYGQQLQSSISEDGKVAREPEDLDL-PGLP--------DSHVGQQYPALE------QPCSEGSKTDLPIQWNEVSSGSSDLSSSKLKCGQ-----RPTVQQARGFGLYSNMVVHPQNLWKVGTGPAGGSQTLGENGSSYSDPEHFAVHSGDGLGPSGDTFHEQAYKTQQYGSQLSRQPLTSSVLDSACGAGIQGSKLKGNSLQENGGLLDFGLSMAPNELADNIVNGIQTQEQMGQGYIAPQLLSGSMQHQGPS---------RPGQQVLGQVGATSHINIYQGTE------SCLPGTQDKIS--QPSSMAVIRGYQPCASYGGSRRQAMPRGSLTLQQGQLSDVSQTSRVNSIKMEAHGQSH-QLCSSMQNYSGQFYDQTMGFSQQDRK------AGSFSLSEANCLLQENGSENSELLSPGVNQVTSTVDSFESHDLEGVQIDFDAIIDDGDHTSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPSLSMSTTNMAIGDMSSLLTSLAEESKFLAVMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61602-1", "uniprot_id": "GLI3_MOUSE", "id": "Q61602-1", "name": "Transcription activator GLI3", "aln": "MEAQAHSSTATERKKAENSIGKCPTRTDVSEKAVASSTTSNEDESPGQIYHRERRNAITMQPQSVQGLNKISEEPSTSSDERASLIKKEIHGSLPHLAEPSLPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHVPSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMD-YIRSLHSSPSLSMISAARGLSPTDAPHA-------------GVSPAEYYHQMALLTGQRSPYADILPSAATAGAGAIHMEYLHAMDSTRFPSP---RLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAIS---------------------------------PALSFTYPSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSS----GPSESSQSKPTSESAVSSTGDPMHN-KRSKIKPDEDLPSPGSRGQQEQ----------------PEGTTLVKEEADKDESKQEPE-VIYETNCHWEGCTREFDTQDQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDMHPRPPPPRDSGSHSQSRSPGRPTQGAFGEQKELSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSVADLSAIDET-PIMDSTISTATTALALQARRNPAGTKWMEHIKLERLKQVNGMFPRLNPILPSKAPAVSPLIGNGTQSNNNYSSGG--PGTLLPSR--SDLSGVDFTVLNTLN-RRDSNTSTISSAYLSSRRSSGISPCFSSRRSSEASQAEG-RPQNVSVADSYDPISTDASRRSSEASQ-GDGLPSLLSLTPVQQYRLKAKYAAATG-GPPPTPLPHMERLSLKTKMALLGE-GRDSGVTLPPVHPPRRCSDGGGHTYRGR-------HLMPHDALANSVRRASDPVRTVSENMSLARVQRFSSLNSFNPPNLPPSVEKRSLVLQNYTRQESSQPRYFQASPCPPSITENVALEALTMDADAN--------LNDEDLLPDDVVQYLNSQNQTGYGQQLQSGISEDSKVAHEPEDLDL-AGLP--------DSHVGQEYPALE------QPCSEGSKTDLPIQWNEVSSGTSDLSSSKLKCGQQ----RPSAQQPRGFGLYNNMVVHPHNLWKVGTGPAGGYQTLGENSSTYNGPEHFAIHSGDGLGTNGNTFHEQPFKTQQYGSQLNRQPLTSSALDHACGTGIQGSKLKGNSLQENGGLLDFSLSVAPNELAGNTVNGMQTQDQMGQGYIAHQLLSGSMQHQGPS---------RPGQQVLGQVGATSHINIYQGTE------SCLPGTQDNSS--QPSSMAAIRGYQPCASYGGNRRQAMPRGNLTLQQGQLSDMSQSSRVNSIKMEAQGQSQ-QLCSTVQNYSGQFYDQTMGFSQQDRK------AGSFSLSDANCLLQGNGTENSELLSPGANQVTSTVDSFESHDLEGVQIDFDAIIDDGDHTSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPSLSMGTTNMAIGDMSSLLTSLAEESKFLAVMQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10071-1", "uniprot_id": "GLI3_HUMAN", "id": "P10071-1", "name": "Transcription activator GLI3", "aln": "MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMD-YIRSLHSSPSLSMISATRGLSPTDAPHA-------------GVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSP---RLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAIS---------------------------------PALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSS----GPSESSQNKPTSESAVSSTGDPMHN-KRSKIKPDEDLPSPGARGQQEQ----------------PEGTTLVKEEGDKDESKQEPE-VIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSIGDLSAIDET-PIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGG--PMTLLPGR--SDLSGVDVTMLNMLN-RRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEG-RPQNVSVADSYDPISTDASRRSSEASQ-SDGLPSLLSLTPAQQYRLKAKYAAATG-GPPPTPLPNMERMSLKTRLALLGD-ALEPGVALPPVHAPRRCSDGGAHGYGRR-------HLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADAN--------LNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDA-PGLP--------DSHAGQQFHALE------QPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGP-----RPAVPQTRAFGFCNGMVVHPQNPLRS--GPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAG---------RPGQQMLGQISATSHINIYQGPE------SCLPGAHGMGS--QPSSLAVVRGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPH-PLCSNLQNYSGQFYDQTVGFSQQDTK------AGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFLAVMQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V6X8-1", "uniprot_id": "G3V6X8_RAT", "id": "G3V6X8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MFNPMTSPQVNSYGEPC----------------------------------------CLRPLPSQGVPSMG--TEGLS-----------------------GLPFCHQANFMSGSQG-YGSARETS-------------SCTEGSLFPPP---RSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFIN-SRCTS-PGGSYGHLSIGTMS---------------------------------PSLGFP------------PQMSHQKGTSPPYGVQPCVPHDS---------TQGSMMLHPQSRGP------RATCQLKSELDIMVG---------KCPEEPLEGDMSSPNSTSTQDH----------------LLGMLDGREDLEREE-KPEPE-SVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDG----PLPRAQPLSTVEP------------KREREGGSGREESRLTVP----EGTM-PQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDLSSLDEG---------PCVAATGLS------TLRRLENLRLDQLHQLR--------PIGSRGLKLPSLTHAGAPVSR------------------------RLGPPVSLD-RRSSSSSSISSAYTVSRRSSLASP-FPPGSPPE------------------------------------NGASSLPGLTPAQHYMLRARYASARGSGTPPTAAHSLDRIGG------------------LPAPPWRSRAEYPGYNPNAG-----------------VTRRASDPARA-ADHPAPARVQRFKSLGCVHT---PPSVATG-RNFDPHLPTS-------VYSPQPPSITENVAMDTRGLQGELE---------VGTSMMGNDLNPYMDFSSADTLGYGGPEGTAAESYGSKGPGSLPLGPGPP---------TNYGPGH----------CAQQVSYPDPTPETWGEFPSHAGVYPGTKALGTAY--------NQCPRLEHYGQVQVKPEQGCPVGSDSTG------------LAPCLNAHPSEGSPDPQPLFSHHSQLPPPQYLQSGPYPQPPHDCLSLESRPGLN----------------------------------FNPSS-HSTGQLKAQLLCNYVQSQQEL-----------LWEGRSRGGIPNQELPYQSPK-------FLGGSQVSQSPTKVPAAAAAATFGSGFAS----PALANHKSVSYPAPSPCHETFTMGVNRPPHRPAAPPR-----LLPPLPPCYGPLKVGDANPSCG-------------HPEVGRLGAG---PALYPPPEGQVCNPLD---SLDLDNTQLDFVAILDE-------AQGLSPPPSHEQGDSSKNTPPP----------SGPPNMAVGNMSVLLGSLPGETQFLNSSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47806-1", "uniprot_id": "GLI1_MOUSE", "id": "P47806-1", "name": "Transcription activator GLI1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MFNPMTPPQVNSYSEPC----------------------------------------CLRPLHSQGVPSMG--TEGLS-----------------------GLPFCHQANFMSGSQG-YGAARETS-------------SCTEGSLFPPPPPPRSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFIN-SRCTS-PGGSYGHLSIGTMS---------------------------------PSLGFP------------PQMSHQKGTSPPYGVQPCVPHDS---------TRGSMMLHPQSRGP------RATCQLKSELDMMVG---------KCPEDPLEGDMSSPNSTGTQDH----------------LLGMLDGREDLEREE-KPEPE-SVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDG----PLPRAQPLSTVEP------------KREREGGSGREESRLTVP----ESAM-PQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDLSSLDEG---------PCVSATGLS------TLRRLENLRLDQLHQLR--------PIGSRGLKLPSLTHAGAPVSR------------------------RLGPPVSLD-RRSSSSSSMSSAYTVSRRSSLASP-FPPGTPPE------------------------------------NGASSLPGLTPAQHYMLRARYASARGSGTPPTAAHSLDRMGG------------------LSVPPWRSRTEYPGYNPNAG-----------------VTRRASDPARA-ADHPAPARVQRFKSLGCVHT---PPSVATG-RNFDPHHPTS-------VYSPQPPSITENVAMDTRGLQEEPE---------VGTSVMGNGLNPYMDFSSTDTLGYGGPEGTAAEPYEARGPGSLPLGPGPP---------TNYGPGH----------CAQQVSYPDPTPENWGEFPSHAGVYPSNKAPGAAY--------SQCPRLEHYGQVQVKPEQGCPVGSDSTG------------LAPCLNAHPSEGSPGPQPLFSHHPQLPQPQYPQSGPYPQPPHGYLSTEPRLGLN----------------------------------FNPSSSHSTGQLKAQLVCNYVQSQQEL-----------LWEGRNRGGLPNQELPYQSPK-------FLGGSQVSQSPAKTPAAAAAA-YGSGFA-----PASANHKSGSYPAPSPCHETFTVGVNRPSHRPAAPPR-----LLPPLSPCYGPLKVGDTNPSCG-------------HPEVGRLGAG---PALYPPPEGQVCNALD---SLDLDNTQLDFVAILDE-------AQGLSPPLSHEQGDSSKNTPSP----------SGPPNMAVGNMSVLLGSLPGETQFLNSSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08151-1", "uniprot_id": "GLI1_HUMAN", "id": "P08151-1", "name": "Transcription activator GLI1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------MFNSMTPPPISSYGEPC----------------------------------------CLRPLPSQGAPSVG--TEGLS-----------------------GPPFCHQANLMSGPHS-YGPARETN-------------SCTEGPLFSSP---RSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFIN-SRCTS-PGGSYGHLSIGTMS---------------------------------PSLGFP------------AQMNHQKGPSPSFGVQPCGPHDS---------ARGGMIPHPQSRGP------FPTCQLKSELDMLVG---------KCREEPLEGDMSSPNSTGIQDP----------------LLGMLDGREDLEREE-KREPE-SVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDG----PLPRAPSISTVEP------------KREREGGPIREESRLTVP----EGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEG---------PCIAGTGLS------TLRRLENLRLDQLHQLR--------PIGTRGLKLPSLSHTGTTVSR------------------------RVGPPVSLE-RRSSSSSSISSAYTVSRRSSLASP-FPPGSPPE------------------------------------NGASSLPGLMPAQHYLLRARYASARGGGTSPTAASSLDRIGG------------------LPMPPWRSRAEYPGYNPNAG-----------------VTRRASDPAQA-ADRPAPARVQRFKSLGCVHT---PPTVAGGGQNFDPYLPTS-------VYSPQPPSITENAAMDARGLQEEPE---------VGTSMVGSGLNPYMDFPPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGPP---------TNYGPNP----------CPQQASYPDPTQETWGEFPSHSGLYPGPKALGGTY--------SQCPRLEHYGQVQVKPEQGCPVGSDSTG------------LAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLD----------------------------------FDSPT-HSTGQLKAQLVCNYVQSQQEL-----------LWEGGGREDAPAQEPSYQSPK-------FLGGSQVSPSRAKAPVN----TYGPGFG-----PNLPNHKSGSYPTPSPCHENFVVGANRASHRAAAPPR-----LLPPLPTCYGPLKVGGTNPSCG-------------HPEVGRLGGG---PALYPPPEGQVCNPLD---SLDLDNTQLDFVAILDE-------PQGLSPPPSHDQRGSSGHTPPP----------SGPPNMAVGNMSVLLRSLPGETEFLNSSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19538-1", "uniprot_id": "CI_DROME", "id": "P19538-1", "name": "Transcriptional activator cubitus interruptus", "aln": "MDAYALPTYFPLAYSELQFLASRRAAAVAAAATVLPGSPCINQHHPTDVSSSVTVPSIIPTGG-----------------------------------------------------------TSDSIKTSIQPQICNENTLLGNAGHQHNHQPQHVHNINVTG------------------------QPHDFHPAYRIPGYMEQLYSLQRTNSASSFHDPYVNCASAFHLAG-----------LGLGSADFLGSRGLSSLGELHNAAVAAAAAGSLASTDFHFSVDGNRRLGSPRPPGGSIRASISRKRALSSSPYSDS-FDINSMIRFSPNSLATIMNGSRGSSAASGSYGHISATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTSASLRVNDVHPNLSDSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPFKDVVPEQPSSTSGGVAQVEADSASSQLSDRCYNNVVNNITGIPGDVKVNSRLDEYINCG-----SISIPSNEYDCANADTTDIKDEPG-DFIETNCHWRSCRIEFITQDELVKHINNDHIQTNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKG-------LPLNDANSRLQQ------------NNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENLNLDDG----------WNCDDDVDVADLPIVLRAMVNIGNGNASAST-----IGGSVLARQRFRGRLQTKGINSST-------------------------IMLCNIPESNRTFGISELNQRITELKMEPGTDAEIKIPKLPN------------------------------------TTIGGYTEDPLQNQTSFRNTVSNKQGTVSGSIQGQFRRDSQNSTASTYYGSMQSRRSSQSSQVSSIPTMRPNPSCNSTAS----------FYDPISPGCSRRSSQMSNGANCNSFTSTSGLPVLNKESNKSLNACINKPNIGVQGVGIYN--------SSLPPPPSSHLIATNLKRLQRKDS----------EYHNFTSGRFSVPSYMHSLHIKNNKPVGENEFDKAIASNARRQTDPVPN---------INLDPLTN---------ISRFSTTPHSFDINVGKTNNIASSINKDNLRKDLFTVSIKADMAMTSDQHPNERINLDEVEELILPDEMLQYLN---------LVKDDTNHLEKEHQAVPVGSNVSETIASNHYREQSNIYYTNKQILTPPSNVDIQP----------------------------------NTTKFTVQDKFAMTAVGGSFSQRELS-----------TLAVPNEHGHAKCESFHHQSQ------KYMNTDIGSKQQSALPSAHQRQTEKSNYN-------QIIDSSMTSLPELNVDSIYPRNETENIFKVHGDHDNEIQCGIISQSQMSPSTNLNNDGQFST---------VNMQPITTSKLFPPEPQKIVCDTQASNTSVMHLDTYQRTLEYVQSCQNWMETNNTSTNQIQSLPGMPVNNTLFPDVSSSTHP----------YHGTNMVINDMTTSLTSLLEENRYLQMMQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .: * . . : . : : . . * ::**:** ** ** :*:: :** **.**.: :* ** :* ..*****:* ::. .: *. : : . . . . . .. . . . . : : : * : : : * *. . **:*:* .* *: :*::**:***.:**: ::* ***:* *:* :**************************** *:******************** ** **.***********************:** **********************.: :..*:::. . . . . **. :*... . * . :. .: .. : : : :. : : :: . .: * * . . : .* . * :.. : .. .. : .: . :: :: : * . . * *. .: . . : . .: . * **. .. . : . . .. . . : . . .: . : : . : . : : . . : . . . . : : : . .:. . *: * : : . . : . . * .**.:.:*: * ** *..:* ", "identical_positions": 178, "similar_positions": 202, "identity": "10.32%" }, { "cls_id": "homologset.agr.FB:FBgn0004860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHM8-1", "uniprot_id": "A0A8I6AHM8_RAT", "id": "A0A8I6AHM8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MFPQPPRRVQRPGLMGLESEHHSWGPWNAIMETESEQNSSSTNGSSSSGASS--------------------------------------------------------RPQIAQMSLYERQ-----AVQALQALQRQPN---------------------------------------------AAQYFHQF--------------MLQQQLSNAQLHSLAAVQQ-------------------------------------ATIAASRQASSPNSSTAQQQTATTQASINLATTSAAQLISRSQSV--SSPSATTLTQSVLLGNTTSPPLNQ-------------SQAQMYLRPQLG---------NLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPAQ---SPGVHADADQVQNLAVRNQQASAQGPQIPGSTQK------------AIPPGASPVSGLSQASSQALAVAQAS-GASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGGLGQLPSSGLAGGNCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEGDGSSQQSVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQATTLAAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPE-------------------------------------------------------------------PTPKPPIPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGA-------------------------VQPGQAHLASSQPSSQ-APGALQECPPALATGMTLAPVQGTAHVVKGGPTASSPVVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEEREDLSALGSVLPTKASPAAESPKVIEEKNSLVEKAE-----------------------------------PVASLNANPPNSDLVALAPTPSAPPPTLALVSRQMGDSKPP-QAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETEKPLP----------AGLPTGLNESQSGGPLGGDSPCVDLDKKAN-------LLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLK---------------RKKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64028-1", "uniprot_id": "PHC1_MOUSE", "id": "Q64028-1", "name": "Polyhomeotic-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSSSTNGSSSSGASS--------------------------------------------------------RPQIAQMSLYERQ-----AVQALQALQRQPN---------------------------------------------AAQYFHQF--------------MLQQQLSNAQLHSLAAVQQ-------------------------------------ATIAASRQASSPNSSTAQQQTATTQASMNLATTSAAQLISRSQSV--SSPSATTLTQSVLLGNTTSPPLNQ-------------SQAQMYLRPQLG---------NLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPAQ---SPGVHADADQVQNLAVRNQQASAQGPQMPGSTQK------------AIPPGASPVSGLSQTSSQALAVAQASSGASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGGLGQLPSSGLTGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQSVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQ-------QQGTTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLTLPPE-------------------------------------------------------------------PTSKPPIPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGSAQAQALGLAQLAAAVPTPRGITGA-------------------------VQPGQAHLASSPPSSQAAPGALQECPPALAAGMTLAPVQGTAHVVKGGPTASSPVVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEERDDLSALASVLPTKASPAAESPKVIEEKNSLGEKAE-----------------------------------PVASLNANPPNSDLVALAPTPSAPPPTLALVSRQMGDSKPP-QAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETKKPLQ----------AGLPTGLNESQPSGPLGGDSPSVELEKKAN-------LLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLK---------------RKKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78364-1", "uniprot_id": "PHC1_HUMAN", "id": "P78364-1", "name": "Polyhomeotic-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSNSTNGSSSSGGSS--------------------------------------------------------RPQIAQMSLYERQ-----AVQALQALQRQPN---------------------------------------------AAQYFHQF--------------MLQQQLSNAQLHSLAAVQQ-------------------------------------ATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV--SSPSATTLTQSVLLGNTTSPPLNQ-------------SQAQMYLRPQLG---------NLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQ---SPGVHADADQVQNLAVRNQQASAQGPQMQGSTQK------------AIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQP------------QATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPD-------------------------------------------------------------------AAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGT-------------------------VQSGQAHLASSPPSSQ-APGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAE-----------------------------------SVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPP-QAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQ----------TGLPTGLTENQSGGPLGVDSPSAELDKKAN-------LLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLK---------------RKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0M3-1", "uniprot_id": "D4A0M3_RAT", "id": "D4A0M3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSRASITTNTSGTNSSSGCSSSSGGGSG----------------------------------------RPTAPQISVYSGIPDRQTVQVIQQALHRQPS--------------------------------------------TAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQ-------------------------------------ASLVANRQGSTSGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVN-SATASGLAQQAVLLGNTSSPALTA-------------SQAQMYLRAQM----------------------------LIFTPTATVATVQPELGTGSPARPP----TPAQVQNLTLRTQQTPA-----------------------AAAAAAASGPAPTQPVLPSLALKPTPSSSQPLPPTPQGRTVVQ----------------------------------------GSPVG--AKPSVTDN-------VTEPLKT-DGNSNMEARPGPDRATVPTVATHQLTAPAYTQ----------------------LQPHQLLPQPS-----------SKHPQPQFVAQQQPQ----------------------PPRPTPQVQSQPQLAAVSPS-----------------------------------------------------------------------------------------------------------------------------LALQPSPEGHAMP------LGPVTQALPLQCSTAHVHKPGS-------------------------SQQCHLPTPDSGSQNGHPEGVSHAPQRRFQHTS-----AVILQLQPASPV-----------PQQCAPDDWKEVVPAEKSVPVTRPGLSPHQQAIITAIPGGLPGPKSPNIQQCPAHETGQGIVH-----------------------------------ALTD------LSSP-GMTSGNGNSASSITGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY---------AQGFLPEKLPQQDHTT-TTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQ-PSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELSDMHMRDLVGMG-HHFLP-SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWH1-1", "uniprot_id": "PHC2_MOUSE", "id": "Q9QWH1-1", "name": "Polyhomeotic-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSNRASVTTNTSGTNSSSGCISSSGGGGGSGG-------------------------------------RPTAPQISVYSGIPDRQTVQVIQQALHRQPS--------------------------------------------TAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQ-------------------------------------ASLVANRQGSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVN-SAAASGLAQQAVLLGNTSSPALTA-------------SQAQMYLRAQM----------------------------LIFTPTATVATVQPELCTGSPARPP----TPAQVQNLTLRTQQTP---------------------------AAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQ----------------------------------------GSPAG--AKPSGTDN-------APETLKAGDGNCNMEGRPGPGRA-VPAVATHPLIAPAYAH----------------------LQSHQLLPQPP-----------AKHPQPQFVAQQQPQ----------------------PPRPAPQVQSQPQLASVSPS-----------------------------------------------------------------------------------------------------------------------------LALQSSPEDHALP------LGSVTQALPLQCSTTHVHKPGN-------------------------SQQCHLPTLDTGSQNGHPEGGSHPPQRRFQHTS-----AVILQVQPASPVT----------PQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGGLPGPKSPNIQQCPAHETGQGIVH-----------------------------------ALTD------LSSP-GMTSGNGNSASSIAGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY---------AQGFLPEKPPQQDHTT-TTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQ-PSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVG-HHFLP-SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8QHL5-1", "uniprot_id": "PHC2_DANRE", "id": "Q8QHL5-1", "name": "Polyhomeotic-like protein 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKEQEQGSVASSASVTIPSTTSVSTSTSAGTLSNSSSR---------------------------------------QQTVPQISVYGGITDRQTVQVIQQALNRQPST-------------------------------------------VAAQYLQQMYAAQQQHLMLQTAALQQQHLS------LAAVQQ-------------------------------------ASIVAGRQSCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSG--SSVPVCIGQQAVLLGNSSTPTLTA-------------SQAQMYLRAQMAQQT------NLVQVARSLGRAVPLSSQLIFTPTASVTAIQPEAPAPSINTPP----TSGQVQNLALRSQQGA-------------------------------LTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAE----------------------------------------PSPQGTAAKASPAET-------SSETTAKNDKTSDLTTSVCPSVT---SVAGHPFISTAYTQ----------------------IQTHQLLQQH----------------KQQFVIQQQPQ----------------------ILQ---RGQAQLLEAAAIHP-----------------------------------------------------------------------------------------------------------------------------HTVQAVAIQSALP------AQPQQCPIPLLPKVPVTCQQAT-------------------------IFHSTTVSQQALAQNGQAHILTHTKAPPLQLT------AVKCQIH---PVQ----------IQQGVAS---QNVP-DKDTPVL---LEPQLLSIPIQEPTRTELRQSD--KESQVKENTQGSVN-----------------------------------VKAG------VGSPPAMTSGSGNNAPTVTGSAPQNGESKPPPQAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQ---------HHAYS----DLQKHN---ADSEMEDLSLQELNNQPEPVR-TCEFCGNVDFAFNFKRSKRFCSTVCAKRYN-----VGCTKRMGLFPGKSS---PEDTKKPKASDESPKNCSTETRKRNPS-IQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFG-----APIEHEESFDHSRELTPLLTQHFLA-SDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6G4B4-1", "uniprot_id": "A0A8I6G4B4_RAT", "id": "A0A8I6G4B4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEAEFKDHSTAMESEPSSGTS-VSTTASSTTTTTITTSSS-------------------------------------------------RMQQPQISVYSGS-DRHAVQVIQQALHRPPS--------------------------------------------SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQ--------------------------------------ASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQAS--SSTSGSITQQTMLLG-STSPTLTA-------------SQAQMYLRAQM----------------------------LIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLG-------------------------VLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPES-------------------------------------KKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQVQSTAQLNLPSHLP-------------------------------------------------------------------LPASPVVHIGPVQQSALVSPGQQIVSPTSHQQYSTLQSSPIPIATPPQMSASPPAQIPPLPLQSMQSLQVQPEI-------------------------LSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEERPEESDECARMDRTPPPP--TLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIK-----------------------------------SPSDPTHVSAPAPPLLMPAASTRSSSTSLASSTPSLENKPP-QAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYN-----VSCSKKFALS----------------RWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSE-----RERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHP6-1", "uniprot_id": "PHC3_MOUSE", "id": "Q8CHP6-1", "name": "Polyhomeotic-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEPSSGTS-VSTTASSTTTTTITTSSS-------------------------------------------------RMQQPQISVYSGS-DRHAVQVIQQALHRPPS--------------------------------------------SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQ--------------------------------------ASLSSGRPSTSPTGSVTQQSSMSQTSI-LSASPAPAQLMNRSQTS--SSTSGSITQQTMLLG-STSPTLTA-------------SQAQMYLRAQM----------------------------LIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLG-------------------------VLSSSQNGSPKSAGQTQSLTICHNKTTVTSSKISQRDPSPES-------------------------------------KKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLLLQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPAPSNAQP-QHCSPVQSHPPPLTVSPNQAQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQTGPNLQQAAADQVQSTAQLNLPSHLP-------------------------------------------------------------------LPASPVVHIGPVQQSALVSPGQQMVSPTSHQQYSALQSSPIPIATPPQMSASPPAQLPPLPLQSMQSLQVQPEI-------------------------LSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECARMDRTPPPP--TLSPAAVTVGRGEDLTSEHPLLEQVELPAVASVSASVIK-----------------------------------SPSDPTHASAPAPPLLIPAASTRSSSTSLASSTPSLENKPP-QAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEIEDMMAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYN-----VSCSKKFALS----------------RWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDVASHEDPVPSAMTTRLRRQSE-----RERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSAMNMKLGPALKICARINSLKDS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDX5-1", "uniprot_id": "PHC3_HUMAN", "id": "Q8NDX5-1", "name": "Polyhomeotic-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTEPNPGTSSVSTTTSSTTTTTITTSSS-------------------------------------------------RMQQPQISVYSGS-DRHAVQVIQQALHRPPS--------------------------------------------SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQ--------------------------------------ASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQAS--SSTSGSITQQTMLLG-STSPTLTA-------------SQAQMYLRAQM----------------------------LIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLG-------------------------VLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESN------------------------------------KKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQS-QHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLP-------------------------------------------------------------------LPASPVVHIGPVQQSALVSPGQQIVSP-SHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEI-------------------------LSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPP--TLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIK-----------------------------------SPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPP-QAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYN-----VSCSKKFALS----------------RWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSE-----RERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W523-1", "uniprot_id": "Q9W523_DROME", "id": "Q9W523-1", "name": "", "aln": "MPHGFGAAPSVSVSGDTESESATTIRTPPPSPEATTSVKVNSTTRVDPQRPLRCLETLAQKAGISFDEDFAKSPSQSPSSKAARGSVGTPSIRRRHPLLPLSSRSPSAPDSKTTGRKLEKSQSPAQQVAAATNVPLQISPEQLQQLYANNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPSNHNQSPQTVLISPVNVISHSPQQQQNLLQSMAAAAQQQQLTQQQQQQLNQQQQQLNQQQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSTVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFWQNAAGLQPFGSNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQHILQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQQSGQLQLSSVPFSVSPSMTAEDIAGITSSALQEALSVSGAIFQTTKPITCSSSTLPTSSVVTITSQSSTPLVTSSTVASMQQAQTQGTQIHQHQQLISATIAGGSQQQQQQQQLGLPSLTPTTPSPTTNPILAMTSMMNATVGHLSTAPPVSVSSTAVTPSSGQLVTLSSASSGGGAGFPATPTKETPSKGPTATLVPIDSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLTTCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSKDLP-KAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEP------------------------PKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVG------VDAMALVDRLDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMPVLAAMSTSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSDRPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKEVPPGDVKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : : : . :: . . ..: : : **:*: * * :: . *. * :: :. : :. :*: . : **. : : .. *: ** * : * : : :: . * *:*:: . : . : : . * : : : .* . : . . : . . . : . : . .: : ... * :*::**::***:*:**:***. ***** : : . ** **. :: **:*: *::: : *.. . * . : : . .:. . : *.*::* ** .* **:: .::* ********:****:**:.:*.:******** *::. :*: ", "identical_positions": 82, "similar_positions": 130, "identity": "5.23%" }, { "cls_id": "homologset.agr.FB:FBgn0004861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHM8-1", "uniprot_id": "A0A8I6AHM8_RAT", "id": "A0A8I6AHM8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPQPPRRVQRPGLMGLESEHHSWGPWNAIMETESEQNSSSTNGSSSSGASS------------------------------------------------------------------------------RPQIAQMSLYERQ-----AVQALQALQRQPN--AAQYFHQF--------------MLQQQLSNAQLHSLAAVQQATIAASRQ------------------------------------ASSPNSSTAQQQTATTQASINLATTSAAQLISRSQSVSSPSATTLTQS-VLLGNTTSPPLNQS--------------QAQMYLRPQLG---------NLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPAQ---SPGVHADADQVQNLAVRNQQASAQGPQIPGSTQK--------AIPPGASPVSGLSQASSQALAVAQAS-GASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGGLGQLPS---SGLAGGNCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEGDGSSQQSVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHR------------QSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQATTLAAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPEPTPKPPIPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGTAQA-------------QALGLAQLAAAVPTSRGMPGAVQPGQAHLASSQPSSQ-APGALQECPPALATGMTLAPVQGTAHVVKGGPTASSPVVAQVPAAFYM-------------------------------------------------------QSVHLPGKAQTLAVKRKAESEEEREDLSALGSVLPTKASPAAESPKVIEEKNSLVEKAEPVASLNANPP---------------------------------------NSDLVALAPTPSAPPPTLALVSRQMGDSKPP-QAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETEKPLP----------AGLPTGLNESQSGGPLGGDSPCVDLDKKAN-------LLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKRKKMKEFQEASYARVRRRGPRRSSSD------------IARAKIQGKRHRGQ------EDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64028-1", "uniprot_id": "PHC1_MOUSE", "id": "Q64028-1", "name": "Polyhomeotic-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSSSTNGSSSSGASS------------------------------------------------------------------------------RPQIAQMSLYERQ-----AVQALQALQRQPN--AAQYFHQF--------------MLQQQLSNAQLHSLAAVQQATIAASRQ------------------------------------ASSPNSSTAQQQTATTQASMNLATTSAAQLISRSQSVSSPSATTLTQS-VLLGNTTSPPLNQS--------------QAQMYLRPQLG---------NLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPAQ---SPGVHADADQVQNLAVRNQQASAQGPQMPGSTQK--------AIPPGASPVSGLSQTSSQALAVAQASSGASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGGLGQLPS---SGLTGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQSVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHR------------QSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQ-------QQGTTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLTLPPEPTSKPPIPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGSAQA-------------QALGLAQLAAAVPTPRGITGAVQPGQAHLASSPPSSQAAPGALQECPPALAAGMTLAPVQGTAHVVKGGPTASSPVVAQVPAAFYM-------------------------------------------------------QSVHLPGKAQTLAVKRKAESEEERDDLSALASVLPTKASPAAESPKVIEEKNSLGEKAEPVASLNANPP---------------------------------------NSDLVALAPTPSAPPPTLALVSRQMGDSKPP-QAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETKKPLQ----------AGLPTGLNESQPSGPLGGDSPSVELEKKAN-------LLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKRKKMKEFQEASYARVRRRGPRRSSSD------------IARAKIQGKRHRGQ------EDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78364-1", "uniprot_id": "PHC1_HUMAN", "id": "P78364-1", "name": "Polyhomeotic-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESEQNSNSTNGSSSSGGSS------------------------------------------------------------------------------RPQIAQMSLYERQ-----AVQALQALQRQPN--AAQYFHQF--------------MLQQQLSNAQLHSLAAVQQATIAASRQ------------------------------------ASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQS-VLLGNTTSPPLNQS--------------QAQMYLRPQLG---------NLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQ---SPGVHADADQVQNLAVRNQQASAQGPQMQGSTQK--------AIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPS---SGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHR------------QSQLLHTATHLQLAQQQQQQQQQQQQQQQP------------QATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA-------------QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQ-APGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYM-------------------------------------------------------QSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTP---------------------------------------SSELVALTPAPSVPPPTLAMVSRQMGDSKPP-QAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQ----------TGLPTGLTENQSGGPLGVDSPSAELDKKAN-------LLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYN-----VSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSD------------IARAKIQGKCHRGQ------EDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A0M3-1", "uniprot_id": "D4A0M3_RAT", "id": "D4A0M3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSRASITTNTSGTNSSSGCSSSSGGGSG------------------------------------------------------------------------------RPTAPQISVYSGIPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVANRQ------------------------------------GSTSGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSATASGLAQQAVLLGNTSSPALTAS--------------QAQMYLRAQM----------------------------LIFTPTATVATVQPELGTGSPARPP----TPAQVQNLTLRTQQTPA-------------------AAAAAAASGPAPTQPVLPSLALKPTPSSSQPLPPTPQGRTVVQ------------------------------------------GSPVG--AKPSVTDNVTEPLKT-DGNS--------NMEARPGPDRATVPTVATHQLTAPAYTQ----------------------LQPHQLLPQPSSKHP--------------------------------QPQFVAQQQPQP---------PRPTPQVQSQPQLAAVSPS----------------------------------------------------------LALQPSPEGHAMP------LGPVT-------------QALPLQCSTAHVHKPGSSQQCHLPTPDSGSQN--------GHPEGVSHAPQRRFQHTS-----AVILQLQPASPV------------------------------------------------------------------PQQCAPDDWKEVVPAEKSVPVTRPGLSPHQQAIITAIPGGLPGPKSPNIQQCPAHETGQGIVHALTD-----------------------------------------LSSP-GMTSGNGNSASSITGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY---------AQGFLPEKLPQQDHTT-TTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELSDMHMRDLVGMG--HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWH1-1", "uniprot_id": "PHC2_MOUSE", "id": "Q9QWH1-1", "name": "Polyhomeotic-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSNRASVTTNTSGTNSSSGCISSSGGGGGS---------------------------------------------------------------------------GGRPTAPQISVYSGIPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVANRQ------------------------------------GSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSAAASGLAQQAVLLGNTSSPALTAS--------------QAQMYLRAQM----------------------------LIFTPTATVATVQPELCTGSPARPP----TPAQVQNLTLRTQQTP-----------------------AAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQ------------------------------------------GSPAG--AKPSGTDNAPETLKAGDGNC--------NMEGRPGPGRA-VPAVATHPLIAPAYAH----------------------LQSHQLLPQPPAKHP--------------------------------QPQFVAQQQPQP---------PRPAPQVQSQPQLASVSPS----------------------------------------------------------LALQSSPEDHALP------LGSVT-------------QALPLQCSTTHVHKPGNSQQCHLPTLDTGSQN--------GHPEGGSHPPQRRFQHTS-----AVILQVQPASPVT-----------------------------------------------------------------PQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGGLPGPKSPNIQQCPAHETGQGIVHALTD-----------------------------------------LSSP-GMTSGNGNSASSIAGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY---------AQGFLPEKPPQQDHTT-TTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVG--HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXK0-1", "uniprot_id": "PHC2_HUMAN", "id": "Q8IXK0-1", "name": "Polyhomeotic-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSG------------------------------------------------------------------------------RPTGPQISVYSGIPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQ------------------------------------GSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTAS--------------QAQMYLRAQM----------------------------LIFTPTATVATVQPELGTGSPARPP----TPAQVQNLTLRTQQTP-----------------------AAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQ------------------------------------------ASPAG--AKPGIADSVMEPHKKGDGNSSV----PGSMEGRAGLSRT-VPAVAAHPLIAPAYAQ----------------------LQPHQLLPQPSSKHL--------------------------------QPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPS----------------------------------------------------------VALQPSSEAHAMP------LGPVT-------------PALPLQCPTANLHKPGGSQQCHPPTPDTGPQN--------GHPEGVPHTPQRRFQHTS-----AVILQLQPASPP-------------------------------------------------------------------QQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTD-----------------------------------------LSSP-GMTSGNGNSASSIAGTAPQNGENKPP-QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY---------AQGFLPEKLPQQDHTT-TTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMG--HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QHL5-1", "uniprot_id": "PHC2_DANRE", "id": "Q8QHL5-1", "name": "Polyhomeotic-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKEQEQGSVASSASVTIPSTTSVSTSTSAGTLSNSSSR-----------------------------------------------------------------------------QQTVPQISVYGGITDRQTVQVIQQALNRQPSTVAAQYLQQMYAAQQQHLMLQTAALQQQHLS------LAAVQQASIVAGRQ------------------------------------SCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSG-SSVPVCIGQQAVLLGNSSTPTLTAS--------------QAQMYLRAQMAQQT------NLVQVARSLGRAVPLSSQLIFTPTASVTAIQPEAPAPSINTPP----TSGQVQNLALRSQQGA---------------------------LTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAE------------------------------------------PSPQGTAAKASPAETSSETTAKNDKTS--------DLTTSVCPSVT---SVAGHPFISTAYTQ----------------------IQTHQLLQQH-------------------------------------KQQFVIQQQPQI------------LQRGQAQLLEAAAIHP----------------------------------------------------------HTVQAVAIQSALP------AQPQQ-------------CPIPLLPKVPVTCQQATIFHSTTVSQQALAQN--------GQAHILTHTKAPPLQLT------AVKCQIHPVQIQ-------------------------------------------------------------------QGVASQN----VP-DKDTPVL---LEPQLLSIPIQEPTRTELRQSD--KESQVKENTQGSVNVKAG-----------------------------------------VGSPPAMTSGSGNNAPTVTGSAPQNGESKPPPQAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQ---------HHAYS----DLQKHN---ADSEMEDLSLQELNNQPEPVR-TCEFCGNVDFAFNFKRSKRFCSTVCAKRYN-----VGCTKRMGLFPG------KSSPEDTKKPKASDESPKNCSTETRKR-NPSIQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFG-----APIEHEESFDHSRELTPLLT-QHFLASDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6G4B4-1", "uniprot_id": "A0A8I6G4B4_RAT", "id": "A0A8I6G4B4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEAEFKDHSTAMESEPSSGTS-VSTTASSTTTTTITTSSS------------------------------------------------------------------------------RMQQPQISVYSGS-DRHAVQVIQQALHRPPS-SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQ-ASLSSGRP------------------------------------STSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQAS-SSTSGSITQQTMLLG-STSPTLTAS--------------QAQMYLRAQM----------------------------LIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLG---------------------VLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPES----------------------------------------KKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQ--------QHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPTSHQQYSTLQSSPIPIATPPQMSASPPAQI-------------PPLPLQSMQSLQVQPEILSQGQVLVQNALVSE--------EELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDV-------------------------------------------------------CEEERPEESDECARMDRTPPPP--TLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVSA-----------------------------------PAPPLLMPAASTRSSSTSLASSTPSLENKPP-QAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYN-----VSCSKKFALSRWN-----RKPDNQSLGHRGRRPSGP----------EGAAREHILRQLPITY--------PSAEEDLASRDDPVPSAMTTRLR-RQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHP6-1", "uniprot_id": "PHC3_MOUSE", "id": "Q8CHP6-1", "name": "Polyhomeotic-like protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEPSSGTS-VSTTASSTTTTTITTSSS------------------------------------------------------------------------------RMQQPQISVYSGS-DRHAVQVIQQALHRPPS-SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQ-ASLSSGRP------------------------------------STSPTGSVTQQSSMSQTSI-LSASPAPAQLMNRSQTS-SSTSGSITQQTMLLG-STSPTLTAS--------------QAQMYLRAQM----------------------------LIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLG---------------------VLSSSQNGSPKSAGQTQSLTICHNKTTVTSSKISQRDPSPES----------------------------------------KKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLLLQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPAPSNAQP---------QHCSPVQSHPPPLTVSPNQAQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQTGPNLQQAAADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQMVSPTSHQQYSALQSSPIPIATPPQMSASPPAQL-------------PPLPLQSMQSLQVQPEILSQGQVLVQNALVSE--------EELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDV-------------------------------------------------------CEEEMPEESDECARMDRTPPPP--TLSPAAVTVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHASA-----------------------------------PAPPLLIPAASTRSSSTSLASSTPSLENKPP-QAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEIEDMMAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYN-----VSCSKKFALSRWN-----RKPDNQSLGHRGRRPSGP----------EGAAREHILRQLPITY--------PSAEEDVASHEDPVPSAMTTRLR-RQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSAMNMKLGPALKICARINSLKDS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDX5-1", "uniprot_id": "PHC3_HUMAN", "id": "Q8NDX5-1", "name": "Polyhomeotic-like protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTEPNPGTSSVSTTTSSTTTTTITTSSS------------------------------------------------------------------------------RMQQPQISVYSGS-DRHAVQVIQQALHRPPS-SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQ-ASLSSGRP------------------------------------STSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQAS-SSTSGSITQQTMLLG-STSPTLTAS--------------QAQMYLRAQM----------------------------LIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLG---------------------VLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESN---------------------------------------KKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQS---------QHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSP-SHQQYSSLQSSPIPIASPPQMSTSPPAQI-------------PPLPLQSMQSLQVQPEILSQGQVLVQNALVSE--------EELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDV-------------------------------------------------------CEEEMPEESDECVRMDRTPPPP--TLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSV-----------------------------------PPPPLLLPAATTRSNSTSMHSSIPSIENKPP-QAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYN-----VSCSKKFALSRWN-----RKPDNQSLGHRGRRPSGP----------DGAAREHILRQLPITY--------PSAEEDLASHEDSVPSAMTTRLR-RQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39769-1", "uniprot_id": "PHP_DROME", "id": "P39769-1", "name": "Polyhomeotic-proximal chromatin protein", "aln": "MDRRALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVISPQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLP-KAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEP------------------------PKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQT-----------EATPKLSESFPILG---ASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* . . : :. . :: *. . :: : **: : * : : . .. * :: :. : :. :*: . . * : . *: ** * : * : : :: . * *:*:: . : . : :: : . : : . .: . : *. . * . . . . . . . . : . .: : ... * :*::**::***:*:**:***. ***** : : . ** **. :: **:*: *::: : *.. . * . .. : .. .. . : *.*::* ** .* **:: .::* ********:****.**:.:*.:******** *::. :*: ", "identical_positions": 80, "similar_positions": 133, "identity": "4.91%" }, { "cls_id": "homologset.agr.FB:FBgn0004862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZY9-1", "uniprot_id": "A0ABK0LZY9_RAT", "id": "A0ABK0LZY9-1", "name": "Homeobox protein Nkx-3.2", "aln": "------------MAVRSSSTLTPFSIQAILNKKE-ERGGLAAPEGRPAPGGTEVAVAAAPAVCCWRLFGETEAGALGGAEDSLLASPARTRTAVGHSAESPGGWDSDSALSEENEGRRRCADVPGASGTGHARVTLGLEQ-----HAAKDLEEEARIRSDSEMSASVSGDHSPRGEDGSVSPGGARVPGLCGTAGGGASSGQAGGVEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLR-------------------------PPSLLPLQPSYYYPYYCFPG--------WALSTCAAAAGTQ-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97503-1", "uniprot_id": "NKX32_MOUSE", "id": "P97503-1", "name": "Homeobox protein Nkx-3.2", "aln": "------------MAVRGSGTLTPFSIQAILNKKE-ERGGLATPEGRPAPGGTEVAVTAAPAVCCWRIFGETEAGALGGAEDSLLASPARTRTAVGQSAESPGGWDSDSALSEENEGRRRCADVPGASGTGRARVTLGLDQPGCELHAAKDLEEEAPVRSDSEMSASVSGDHSPRGEDDSVSPGGARVPGLRGAAGSGASGGQAGGVEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLR-------------------------PPSLLPLQPSYYYPYYCLPG--------WALSTCAAAAGTQ-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78367-1", "uniprot_id": "NKX32_HUMAN", "id": "P78367-1", "name": "Homeobox protein Nkx-3.2", "aln": "------------MAVRGANTLTSFSIQAILNKKE-ERGGLAAPEGRPAPGGTAASVAAAPAVCCWRLFGERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLR-------------------------PPSLLPLQPSYYYPYYCLPG--------WALSTCAAAAGTQ-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22809-1", "uniprot_id": "BAGP_DROME", "id": "P22809-1", "name": "Homeobox protein bagpipe", "aln": "MLNMESAGVSAAMAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQ----------PSNYLQYYAAAMDNNNHHHQATGTSNS-------------------SAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSP-----PPLSSSPSESPLSHDGSGLS----------RKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMSVESGAESVHSAAEDVDENVEID", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . . *.***: **.:.: * ::: :..* * : ::. : : * :: . : ..* * .: . * : :*:.::: * . * :: * :. .* ::*.:. :.. :.. .* . * . .. . . .. . ********************* :*********:::* **:*******************:*: . * *:*:*.*:****:* . . * . : : .*:** : .* :: *.::*:.: ", "identical_positions": 93, "similar_positions": 93, "identity": "21.83%" }, { "cls_id": "homologset.agr.FB:FBgn0004863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A270-1", "uniprot_id": "D4A270_RAT", "id": "D4A270-1", "name": "", "aln": "-----------------------------------------------MEHLG-PHHLHPGHAEPIS-FGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAGAGAGGTGAYGTGGPGGPGGPAGGGGGACSMGPLAGSYNVNMALAGGPGPGGGGGGAGAGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLP-TVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPA--DPLCVHNSSLFALQNLQPWS-DDSTKITSVTSVASACE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31314-1", "uniprot_id": "TLX1_HUMAN", "id": "P31314-1", "name": "T-cell leukemia homeobox protein 1", "aln": "-----------------------------------------------MEHLG-PHHLHPGHAEPIS-FGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGG-ACSMGPLTGSYNVNMALAGGPGPGGGGGSS--GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLP-TVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFT--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPA--DPLCVHNSSLFALQNLQPWS-DDSTKITSVTSVASACE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43345-1", "uniprot_id": "TLX1_MOUSE", "id": "P43345-1", "name": "T-cell leukemia homeobox protein 1", "aln": "-----------------------------------------------MEHLG-PHHLHPGHAEPIS-FGIEQILNSPDQGGCMGPNSRLQDGDYGLGCLVPGAYTYGGGGSAAGAGAGGTGAYGAGGPGGPGGPAGGGGGACSMGPLPGSYNVNMDLAGGPGPGGDGGGGG-AARRALSAAGVIRVPAHRPLAGAVAHPQPLATGLP-TVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRFT--------------GLPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAESEQANRILLQLQQEAFQKSLAQPLPA--DPLCVHNSSLFALQNLQPWS-DDSTKITSVTSVASACE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6M6-1", "uniprot_id": "G3V6M6_RAT", "id": "G3V6M6-1", "name": "", "aln": "MTQSLSGPRTLGKVSVRLEAPGAPWPRRNGDPAASPPSPAQPFRPPRMEAPASAQTPHP--HEPIS-FGIDQILNSPDQDS--------APAPRGPDGAS---YLGGPPGGRPGAAYPSLPAS-FAGLGAPFEDA-------------GSYSVNLSLAP---------------------AGVIRVPAHRPLPGAV--PPPLPS----ALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFALQNLQPWE-EDSSKVPAVTSLV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55144-1", "uniprot_id": "TLX3_MOUSE", "id": "O55144-1", "name": "T-cell leukemia homeobox protein 3", "aln": "-----------------------------------------------MEAPASAQTPHP--HEPIS-FGIDQILNSPDQDS--------APAPRGPDGAS---YLGGPPGGRPGAAYPSLPAS-FAGLGAPFEDA-------------GSYSVNLSLAP---------------------AGVIRVPAHRPLPGAV--PPPLPS----ALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFALQNLQPWE-EDSSKVPAVTSLV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43711-1", "uniprot_id": "TLX3_HUMAN", "id": "O43711-1", "name": "T-cell leukemia homeobox protein 3", "aln": "-----------------------------------------------MEAPASAQTPHP--HEPIS-FGIDQILNSPDQDS--------APAPRGPDGAS---YLGGPPGGRPGATYPSLPAS-FAGLGAPFEDA-------------GSYSVNLSLAP---------------------AGVIRVPAHRPLPGAV--PPPLPS----ALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFALQNLQPWE-EDSSKVPAVTSLV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PA75-1", "uniprot_id": "A0A8M1PA75_DANRE", "id": "A0A8M1PA75-1", "name": "", "aln": "-----------------------------------------MDRAPSSSPSGTSQTSQPTQHEPIS-FGIDQILSGTDQESQQNSTRNSSESSSGSSSASGGCYHLGSPTGASATPYTTLTGT-FHGIAAPYEES-------------SPYGMNLTLAP---------------------GGVIRVPAHRPLAAAV--PPPMAS----AVPG---------LGSLSFPWMESSQRFAKDRF--AAALTPFTVARRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKTLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMIQLQHDAFQKSLTDSVPT--DPLCIHNSSLFALQNLQPWASEESSKLGGVTALV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JVZ2-1", "uniprot_id": "A0A0G2JVZ2_RAT", "id": "A0A0G2JVZ2-1", "name": "", "aln": "-----------------------------------------------MEPAVLAPHHLP-HHEPIS-FGIDQILSGPEPPG----------GGLGPGQVG----QSQGESAAFSSGFHGTSGYAPAGSLASLPRG-------------------SGVGP---------------------GGVIRVPAHRPVPVPP--PSGAAP----AVAGPSGLGGPGGLAGLTFPWMDSGRRFAKDRLT--AALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPP--DPLCLHNSSLFALQNLQPWA--EDNKVASVSGLASVV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61663-1", "uniprot_id": "TLX2_MOUSE", "id": "Q61663-1", "name": "T-cell leukemia homeobox protein 2", "aln": "-----------------------------------------------MEPAVLAAHHLP-HHEPIS-FGIDQILSGPEPPG----------GGLGPGQSG----QSHGESAAFSSGFHGASGYAPAGSLASLPRG-------------------SGVGP---------------------GGVIRVPAHRPLPVPP--PSGAAP----AVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLT--AALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPP--DPLCLHNSSLFALQNLQPWA--EDNKVASVSGLASVV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43763-1", "uniprot_id": "TLX2_HUMAN", "id": "O43763-1", "name": "T-cell leukemia homeobox protein 2", "aln": "-----------------------------------------------MEPGMLGPHNLP-HHEPIS-FGIDQILSGPETPG----------GGLGLGRGG----QGHGENGAFSGGYHGASGYGPAGSLAPLPGS-------------------SGVGP---------------------GGVIRVPAHRPLPVPP--PAGGAP----AVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLT--AALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPP--DPLCLHNSSLFALQNLQPWA--EDNKVASVSGLASVV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KS72-1", "uniprot_id": "Q7KS72_DROME", "id": "Q7KS72-1", "name": "", "aln": "----------------------------------------------MSSHEEDDHEHENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSESLQSEQTRSSSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLA-----AAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQGGVNGAPLAALHGLQPWA--EASHAAGC--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :. *. :.. . . . . . . . . * .:: . . * .. : : :: .***: * *********:*******:* *: ***:** :*************: *:**************************** . *.*::: ** :*: : : . . . ::.:.* **:.**** : .: . ", "identical_positions": 85, "similar_positions": 58, "identity": "21.25%" }, { "cls_id": "homologset.agr.FB:FBgn0004864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62689-1", "uniprot_id": "JAK2_RAT", "id": "Q62689-1", "name": "Tyrosine-protein kinase JAK2", "aln": "-----MGMACLTMTEMEGTSTSPAHQNGDIPGNANSVKQTEPVLQVYLYHSLGQAEGDYLKFPNGEYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNILYRIRFYFPHWYCSG--SNRTYRYGVSRG----------AEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQE------ECLGMAVLDMMRIAKEKDQ-TPLAVYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFS-----QCKATARNLKLKYLINLET--LQSAFYTEQFEVKESARGPSGE-----------------------EIFATIIITGNGGIQWSRGKHKESET--------------------------------LTEQDLQLYCDFPDIIDVSIKQANQECST-ESRVVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVE------RENVIEYKHCLITKNEN-GEYNLSGTKRNFSSLKDLLNCYQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVQLSPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDY-----------------GQLHETEVLLKVLDKAHRNYSESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIEN--PKNLTLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELA-----NLINTCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTEN-DMLPN-----------MRIGALGFSGAFEDRDPTQFEERHLKFLQ-QLGKGNFGSVEMCRYDPLQ-DNTGEVVAVKKLQHS-TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENR---VKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDLSLRVDQIRDSMAA--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62120-1", "uniprot_id": "JAK2_MOUSE", "id": "Q62120-1", "name": "Tyrosine-protein kinase JAK2", "aln": "-----MGMACLTMTEMEATSTSPVHQNGDIPGSANSVKQIEPVLQVYLYHSLGQAEGEYLKFPSGEYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHDILYRIRFYFPHWYCSG--SSRTYRYGVSRG----------AEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQE------ECLGMAVLDMMRIAKEKDQ-TPLAVYNSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFS-----QCKATARNLKLKYLINLET--LQSAFYTEQFEVKESARGPSGE-----------------------EIFATIIITGNGGIQWSRGKHKESET--------------------------------LTEQDVQLYCDFPDIIDVSIKQANQECSN-ESRIVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVE------RENVIEYKHCLITKNEN-GEYNLSGTKRNFSNLKDLLNCYQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDY-----------------GQLHKTEVLLKVLDKAHRNYSESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIEN--PKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELA-----NLINNCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTEN-DMLPN-----------MRIGALGFSGAFEDRDPTQFEERHLKFLQ-QLGKGNFGSVEMCRYDPLQ-DNTGEVVAVKKLQHS-TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENR---VKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIELLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDLSLRVDQIRDSIAA--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60674-1", "uniprot_id": "JAK2_HUMAN", "id": "O60674-1", "name": "Tyrosine-protein kinase JAK2", "aln": "-----MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSG--SNRAYRHGISRG----------AEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQE------ECLGMAVLDMMRIAKENDQ-TPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFS-----QCKATARNLKLKYLINLET--LQSAFYTEKFEVKEPGSGPSGE-----------------------EIFATIIITGNGGIQWSRGKHKESET--------------------------------LTEQDLQLYCDFPNIIDVSIKQANQEGSN-ESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVE------RENVIEYKHCLITKNEN-EEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDY-----------------GQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIEN--PKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELA-----NLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTEN-DMLPN-----------MRIGALGFSGAFEDRDPTQFEERHLKFLQ-QLGKGNFGSVEMCRYDPLQ-DNTGEVVAVKKLQHS-TEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENR---VKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QWX8-1", "uniprot_id": "F1QWX8_DANRE", "id": "F1QWX8-1", "name": "Tyrosine-protein kinase", "aln": "--------MMLANTENEQKQAS------------------GAALQVRLYCCRDGAG--VISYPAGEYTAEELSVTAAKQCGVSPVHCALFGLMRERDRVWLPPNHIFKIEPSANETLLFRVRFYFPGWYGSG--CSSARRYGLSRS----------SEAPVCDDITTAYLCAQWRSDFLSGAVSVPVSLEFQE------ECLGLAVLDIMRLAKEKGK-SPVDIYNHSSYKSFLPKNMREHIQNQHLVTRKRIRFRFRRFLQQFG-----SCKAAPRELKLKYVVSLET--LQPAFYSEHFRVSEASAGS-----------------------------VTIVVSGDRGIQWCRAAAPEPE-------------------------------------DLQVYCDFSDVIDISIKQGTKDGSV-ENRIVTINRQDSQTLELEFQSLSEALSFVSLIDGYYRLTTDAHHYLCKEVAPPRLLEAIQINCHGPLSTEFAVSRLRRCEGQPGVYILRCSPKDYDRYFLSFMVE------AEGQLELKHCLVLRSLS-GEFVLSGARCSFSSLSELLARYQKEALRSDTHVFQLRRCCPPRSKDKSNLLVCRTHQGSEVCAPSSEHR--LVNQMIFHKIHREDLQTTEGLGQGTFTQVFRGIRREVGDY-----------------GEVHKMEVVMKILDKSHRNYTESFFESASMMSQLSHKHLLLNYGICVCADEHIMVQEYVRFGSLDTYLKRNRNTINITWKLEVAKQLAWALHHLEEKSLTHGNVCARNVLVTREEDRKTGTPPFIKLSDPGISITVQPREILLERIPWVPPECVKD--SRNLSLAADKWSFGTTLWEIYCGGEQPLAAYDTAKKLLFYEDKHQLPAPKWTELA-----SVINSCMDYEPLHRPSFRALIRDLNSLYTPDYELLVES-DTVP------------SRHRGPGLAGAFESQEPTQFQARHLIFLQ-LLGKGNFGSVEKCRYDPLQ-DNTGEVVAVKKLQHS-TAEHLRDFEREIEILRSLQHENIVRYKGVCYSAGRNNLRLVMEFLPFGSLRDYLSKNRERFDHSKLLLYASQICKGMDYLAEKRYVHRDLATRNILVESEFR---VKIGDFGLTKVLPQDKEYYTVREPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYSEKSCSPPAVFMEQMGEDKQGQMIVYHLIDLLKRNYRLPAPDGCPAEIHALMKQCWAPEPADRPLFRDLARTVEDIQDSQSG--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63272-1", "uniprot_id": "JAK3_RAT", "id": "Q63272-1", "name": "Tyrosine-protein kinase JAK3", "aln": "-----MAPPSEETPLISQRSCS--------------LSSSEAGALHVLLPPRGPGPPQRLSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDLSCWFPPSHIFSIEDVDTQVLVYRLRFYFPGWFG----LETCHRFGLHKD----------LTSAILDVHVLEHLFAQHRSDLVSGRLPVGLSLKDQG------EFLSLAVLDLAQMARKQAQ-RPGELLKSVSYKACLPPSLRDLIQGQSFVTRRRIRRTVVQALRRVV-----ACQADRYALMAKYILDLER--LHPAATTESFLVGLPGAQ---------------------------EEPGCLRVTGDNGIAWSSKDQ----------------------------------------ELFQTFCDFPEIVDVSIKQAPRVGPAGEHRLVTITRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHFFCKEVAPPRLLEEEAELCHGPITLDFAIHKLKAAGSLPGSYILRRSPQDYDSFLLTACVQ------TPLGPDYKGCLIRQDPS-GAFSLVGLSQLHRSLQELLTACWHSGLQVDGTALNLTSCCVPRPKEKSNLIVVRRGRNPTPAPGHSP-SCCALTKLSFHTIPADSLEWHENLGHGSFTKIFHGHRREVVD------------------GETHDTEVLLKVMDSRHQNCMESFLEAASLMSQVSYPHLVLLHGVCMAG-DSIMVQEFVYLGAIDTYLRKRGHLVPASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLARE--GVDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQE--AGTLNLEADKWGFGATTWEVFSGAPMHITSLEPAKKLKFYEDRGQLPALKWTELE-----GLIAQCMAYDPGRRPSFRAILRDLNGLITSDYELLSDPTPGIPN-----------PRDELCGGAQLYACQDPAIFEERHLKYIS-LLGKGNFGSVELCRYDPLG-DNTGPLVAVKQLQHS-GPEQQRDFQREIQILKALHCDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLHNDRLLLFAWQICKGMEYLGARRCVHRDLAARNILVESEAH---VKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYSDKSCSPSTEFLRMMGPEREG-SPLCHLLELLAEGRRLPPPSTCPTEVQELMQLCWSPNPQDRPAFDTLSPQLDALWRGSPG--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62137-1", "uniprot_id": "JAK3_MOUSE", "id": "Q62137-1", "name": "Tyrosine-protein kinase JAK3", "aln": "-----MAPPSEETPLIPQRSCS--------------LSSSEAGALHVLLPPRGPGPPQRLSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDFSCWFPPSHIFCIEDVDTQVLVYRLRFYFPDWFG----LETCHRFGLRKD----------LTSAILDLHVLEHLFAQHRSDLVSGRLPVGLSMKEQG------EFLSLAVLDLAQMAREQAQ-RPGELLKTVSYKACLPPSLRDVIQGQNFVTRRRIRRTVVLALRRVV-----ACQADRYALMAKYILDLER--LHPAATTETFRVGLPGAQ---------------------------EEPGLLRVAGDNGISWSSGDQ----------------------------------------ELFQTFCDFPEIVDVSIKQAPRVGPAGEHRLVTVTRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHYFCKEVAPPRLLEEEAELCHGPITLDFAIHKLKAAGSLPGTYILRRSPQDYDSFLLTACVQ------TPLGPDYKGCLIRQDPS-GAFSLVGLSQPHRSLRELLAACWNSGLRVDGAALNLTSCCAPRPKEKSNLIVVRRGCTPAPAPGCSP-SCCALTQLSFHTIPTDSLEWHENLGHGSFTKIFRGRRREVVD------------------GETHDSEVLLKVMDSRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAG-DSIMVQEFVYLGAIDMYLRKRGHLVSASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLARE--GGDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQE--AQTLCLEADKWGFGATTWEVFSGGPAHITSLEPAKKLKFYEDQGQLPALKWTELA-----GLITQCMAYDPGRRPSFRAILRDLNGLITSDYELLSDPTPGIPS-----------PRDELCGGAQLYACQDPAIFEERHLKYIS-LLGKGNFGSVELCRYDPLG-DNTGPLVAVKQLQHS-GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLHTDRLLLFAWQICKGMEYLGARRCVHRDLAARNILVESEAH---VKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGPEREG-PPLCRLLELLAEGRRLPPPPTCPTEVQELMQLCWAPSPHDRPAFGTLSPQLDALWRGRPG--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52333-1", "uniprot_id": "JAK3_HUMAN", "id": "P52333-1", "name": "Tyrosine-protein kinase JAK3", "aln": "-----MAPPSEETPLIPQRSCS--------------LLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFG----LEKCHRFGLRKD----------LASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQG------ECLSLAVLDLARMAREQAQ-RPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVA-----ACQADRHSLMAKYIMDLER--LDPAGAAETFHVGLPGALG-GH-----------------------DGLGLLRVAGDGGIAWTQGEQ----------------------------------------EVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQ------NPLGPDYKGCLIRRSPT-GTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVD------------------GEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAG-DSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLARE--GADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLRE--AQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELA-----LLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALA-----------PRDGLWNGAQLYACQDPTIFEERHLKYIS-QLGKGNFGSVELCRYDPLG-DNTGALVAVKQLQHS-GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAH---VKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDV-PALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LYP8-1", "uniprot_id": "A0ABK0LYP8_RAT", "id": "A0ABK0LYP8-1", "name": "Tyrosine-protein kinase", "aln": "--MVTSMPLCGRRAASEDSKADG---------TEAQPLVPTGRLMVLLHWPGPEGGEPWVTFSQPSLTAEEMCIHIAHKVGITPPCLNLFALYDAQAKVWLPPNHVLDTSQDATLRLYFRMRFYFRNWHGMNPQEPAVYRCGFPGAETSSD--HAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHLCHLALNRGV-PLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLRRVFRRFLQAFQ-----PGHLSQQVVMVKYLATLER--LAPRFGSEHIPVCHLEVLAQPERDPCYIQNSGQTTGDPGPELASGPATHEVLVTGTGGIQWRPLQTQDSER----GHSRGNPQGSQSGKKPKAPESGEHLAGSPQEPPWTYFCDFQDISHVVLKER----------RVHIHLQDNKCLLLCLCSQAEALSFVALVDGYFRLTADSSHYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWP---EDGLYLIQWSTSHLHRLILTVAHRNPASRNGPRGLRLRKFPITQQP--GAFVLDGWGRSFDSLGDLRQALQGCSLRAGDDCFPLHHCCLPRPREISNLVIMRG--------SRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLSVGG---PNEGKVDSGCPSGPDRGSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHLAFLHGVCVRGSENIIVAEFVEHGPLDVWLRRQRGRVPMPWKMVVAQQLASALSYLEDKNLVHGNVCGRNILLARLG-LEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLSGG-ANSLGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSCPELA-----TLTRQCLSYEPAQRPSFRTILRDLTRLQPQNLVGTSTV-------------------------NSDSPASDPTVFHKRYLKRIR-DLGEGHFGKVSLYCYDPNN-DGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPR--HSVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSSQSPPTKFIELIG-VTQGQMTVLRLTELLERGERLPRPDRCPCEVSPDRCSPFPPSSQGKWPHSPISPADLSPHEELLGVRGLLPAHVPESCAHP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R117-1", "uniprot_id": "TYK2_MOUSE", "id": "Q9R117-1", "name": "Non-receptor tyrosine-protein kinase TYK2", "aln": "--MVGTMPLCGRRAILEDSKADG---------TEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEEVCIHIAHKVGITPPCLNLFALYNAQAKVWLPPNHILDTSQDMN--LYFRMRFYFRNWHGMNPQEPAVYRCGFPGAETSSD--RAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHLCHLALSRGV-PLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLRAFR-----PGHLSQQVVMVKYLATLER--LAPRFGSERIPVCHLEVLAQPERDPCYIQNSGQTAGDPGPELPSGPPTHEVLVTGTGGIQWHPLQTQESER----GNSRGNPHGSRSGKKPKAPKAGEHLTESPQEPPWTYFCDFQDISHVVLKER----------RVHIHLQDNKCLLLCLCSQAEALSFVALVDGYFRLTADSSHYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWP---EDGLYLIQWSTSHLHRLILTVAHRNPAFSNGPRGLRLRKFPITQQP--GAFVLDGWGRSFASLGDLRLALQGCSLRAGDDCFPLHHCCLPRPREISNLVIMRG--------SRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRVGG---PDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMVVAQQLASALSYLEDKNLVHGNVCGRNILLARLG-LEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLSGG-TSSLGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSSPELA-----TLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGTSAV-------------------------NSDSPASDPTVFHKRYLKKIR-DLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPR--HCVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSNQSPHMKFTELIG-HTQGQMTVLRLTELLERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPILQTAQEKYQG-------QVPSVFSVC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29597-1", "uniprot_id": "TYK2_HUMAN", "id": "P29597-1", "name": "Non-receptor tyrosine-protein kinase TYK2", "aln": "------MPLR-HWGMARGSKPVG---------DGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSD--QTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGI-PLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQ-----PGRLSQQMVMVKYLATLER--LAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEH----------CVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP-DGMQSLRLRKFPIEQQD--GAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG--------ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG-LAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA-----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV-------------------------NPDSPASDPTVFHKRYLKKIR-DLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG-IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG-------QAPSVFSVC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V9W2-1", "uniprot_id": "G3V9W2_RAT", "id": "G3V9W2-1", "name": "Tyrosine-protein kinase", "aln": "MQYLNIKEDCNAMAFCAKMRSFKK--------TEVKQVAPEPGVEVTFYLLDREP----LRLGSGEYTAEELCIRAAQECSISPLCHNLFALYDESTKLWYAPNHIITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKM-QLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLET--LTKHYGAEIFETSMLLISSENELSRCHSNDSG------------NVLY-EVMVTGNLGIQWRQKPNVLPVE---------KEKNKLKRKKLDYNKHKKEDDRNKLREEWNSFSYFPEITHIVIKES----------VVSINKQDNKNMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVSCFEKSE-VLGNQKQFKNFQIEVQK--GRYSLHGSVDHFPSLRDLMNHLKKQILRTDNISFVLKRCCQPKPREISNLLVATK-------KAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGTLLDYK---DDEGIAE-----------EKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREG-IDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVED--SKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELA-----DLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPD-IVSE-------------------------KQPITEVDPTHFEKRFLKRIR-DLGEGHFGKVELCRYDPEG-DNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQ---VKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDFSPMALFLKMIG-PTHGQMTVTRLVNTLKEGKRLSCPPNCPDEVYQLMRKCWEFQPSNRTTFQNLIEGFEALLK------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52332-1", "uniprot_id": "JAK1_MOUSE", "id": "P52332-1", "name": "Tyrosine-protein kinase JAK1", "aln": "MQYLNIKEDCNAMAFCAKMRSFKK--------TEVKQVVPEPGVEVTFYLLDREP----LRLGSGEYTAEELCIRAAQECSISPLCHNLFALYDESTKLWYAPNRIITVDDKTSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKM-QLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDS--SVHDLKVKYLATLETSTLTKHYGAEIFETSMLLISSENELSRCHSNDSG------------NVLY-EVMVTGNLGIQWRQKPNVVPVE---------KEKNKLKRKKLEYNKHKKDDERNKLREEWNNFSYFPEITHIVIKES----------VVSINKQDNKNMELKLSSREEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSE-VLGGQKQFKNFQIEVQK--GRYSLHGSMDHFPSLRDLMNHLKKQILRTDNISFVLKRCCQPKPREISNLLVATK-------KAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGTLLDYK---DEEGIAE-----------EKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREG-IDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVED--SKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELA-----DLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPD-IVSE-------------------------KQPTTEVDPTHFEKRFLKRIR-DLGEGHFGKVELCRYDPEG-DNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQ---VKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDFSPMALFLKMIG-PTHGQMTVTRLVKTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTTFQNLIEGFEALLK------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23458-1", "uniprot_id": "JAK1_HUMAN", "id": "P23458-1", "name": "Tyrosine-protein kinase JAK1", "aln": "MQYLNIKEDCNAMAFCAKMRSSKK--------TEVNLEAPEPGVEVIFYLSDREP----LRLGSGEYTAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKM-QLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLET--LTKHYGAEIFETSMLLISSENEMNWFHSNDGG------------NVLYYEVMVTGNLGIQWRHKPNVVSVE---------KEKNKLKRKKLEN-KHKKDEEKNKIREEWNNFSYFPEITHIVIKES----------VVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQKQFKNFQIEVQK--GRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATK-------KAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSGTLMDYK---DDEGTSE-----------EKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREG-IDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVED--SKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELA-----DLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPD-IVSE-------------------------KKPATEVDPTHFEKRFLKRIR-DLGEGHFGKVELCRYDPEG-DNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQ---VKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIG-PTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O12990-1", "uniprot_id": "JAK1_DANRE", "id": "O12990-1", "name": "Tyrosine-protein kinase JAK1", "aln": "MPELAVMDLG--RQLCVKMKKQRK--------AEMTIPTAMKGLEIHFYLADTHQ----LEFFKACYTAEDLCVEAAKRCRISPLCHNLFALYEESQDLWYAPNHVFKVTDETSIKLHYRMRFYFTNWHGTSEIESPVWRHTLSKQKSVLNSQKTTEGTPLLDAASLDYLFAQGQYDFLRGLSPVRPTQTDEEHHEIENECLGMAVLAITHHAKSNNL-PLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRISNVFKNFLNEFNSKTIQDSNIGLYDLKVKYLSTLET--LTQGVGREIFKPKNLKVTGESEGSPAQMLPLGD-----------NGMGYEVQVYGTTGISWRRKP-APNQL---------ILKDKPKSKKIKGDKQWNDKKKD---SGWTLFSDFHEITHIVIKDC----------CVTIYRQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHYLCTDVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTEYNFIIMTVVCIELDLCESRPVPQYKNFQIETSP--QGYRLYGTDTFRPTLKELLEHLQGQLLRTDNLRFQLRRCCPPQPREISNLLVMTTD------REPVPQKKTQVSQLSFDRILKEEIVQGEHLGRGTRTNIYAGILKPKS---DDEDDLGG---------YSQEVKVVLKVLGSGHRDISLAFFETASMMRQISHKHTALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSYLEDKKMVHGYVCSKNILVARDG-LDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKD--TANLTIAADKWSFGTTLWEICYNGEIPLKDKKLSEKERFYAAQCQLATPDCDELA-----KLMTHCMTYDPRQRLFFRAIVRDIVMVEKQNPS-IQP---------------------------VPMLEVDPTVFEKRFLKKIR-DLGEGHFGKVELCRYDPRG-DRTGELVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGICNEEGGRSIKLIMEFLPAGSLKEYLPRNKAHINLKTLHNYSVQICQGMDYLGSRNYIHRDLAARNVLVENEGT---VKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVWSFGVTMYELLTYCDASCSPMSVFLKLIG-PTHGQMTVTRLVKVLEEGKRLPRPDDCSEQLYNLMRRCWEATPEKRIDFKSLIANFQQMLDNL----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24592-1", "uniprot_id": "JAK_DROME", "id": "Q24592-1", "name": "Tyrosine-protein kinase hopscotch", "aln": "-----MALANGGEDRMDDSSSGR--------------TSLADSASLTNSSLRSGTSSQSIHTNDGTIRVFNFTTGEFERFHPNMLCEEICNTMCRQLGIAPIAQLLYGIREHSTSRRPSPLVRLDLTWCLPGERLNCQLVYCFRMRFRVP---ELDSQLELIDGRSHKFLYRQMRYDMRTEQIPEIRYPEHKD------KSTGLAVMDMLIDDQEQSEDQQAMRSIEKLYKLYLPPSLWR---AHSFFVGSKIREVFRSLK---------ANSLSVERLKWHYVHQVSH--LAPTYMTEQFTCTVQYLPNEEVARGSGPIGTSLAHSTSTLASSGSTNTLSTLTTNTNSVALGGSGKKAKRR-----------STSGGIDVYVRVFPHDSLEPGLKVARVTSEATLKWILVGAVEGIFMISKINDTSVRLEIVGLPKGYEMQFQTEKEMKSFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCHGPIGGAYSLMKLHENGDKCGSYIVRECDREYNIYYIDINTKIMAKKTDQERCKTETFRIVRKDSQWKLSYNNGEHVLNSLHEVAHIIQADSPD----RYRIPASKYDKPPLLLLLLPKNLKAKKTDLQLSEAELQRRNPQIFNPRTDLQWYPDSISLSDDGMMFTMRGDWIQQSP--------------------VKDVSVTMKMLKSDGN--FMEFFRLAQTWSLIQSPQFLKLYGLTLAD-PYTMVMEYSRYGPLNKFLHSMPN-VTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYD-------PNSYVLDAKISDPGYPRPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTM---QVSTDFHREIGIMRTLSHPNIVKFK----YWAEKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGDCVKISDFGLAQFANSD-GYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFEMFSRGEEPN------------LVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITREVATKVTHPTDGHQSPPNQPTDAE---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. . : .. : * : * .* * : :: : : .:*.: : . :* :* . .. :: . : :*: :. * * . . .: . : : :: : : ** : :. * ** . : :* . .. : ***: : :* * *::: . . : . : . . .: :: : . :. *: :: . *. . * :. * :*:: . * . *. :. : :*: : :* *: *.:: ::: : : : : *. .: .**:: : *. : :: : : * : *. : . . ** . : . . : *.*.:* *: : . . :: : * .: :. : : * . * : : :*.*::*.* : * . **:* *: : . :** *:: * *:::: . .. ::**:: *.: :* . :: :*.:** ** :*****:**:*:: : ***.****:: . ** .:. : *: **:**.: * *****:**.:.*::: : : . * . ** * *. : : : . : ", "identical_positions": 107, "similar_positions": 220, "identity": "8.31%" }, { "cls_id": "homologset.agr.FB:FBgn0004865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63504-1", "uniprot_id": "NR1D2_RAT", "id": "Q63504-1", "name": "Nuclear receptor subfamily 1 group D member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELNAGGVIAYIS--------------------------------SSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNCDANGNPKNTDVSSIDG---------------------VLKSDRTDCPVKTGKPGAPGMTKSHSGMTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMSTQFGGHLQSDTLAEPHEQSVPPAQEQLRPKPQLEQENIK-STPPPSDFAKEEVIGMVTRAHKDTFLYNQEHRENSSESMPPHRGERIPRNVEQYNLNHDHRG-----GGLHSHFPCSESQQHLSGQYKGRNMMHYPNGHTVCISNGHCVNFSSAYPQRVCDRIPVGGCSQTESRNSYLCSTGGRMHLVCP---MSKSPYVDPQKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLSSMFEFSEKLNGLQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKN---HPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60674-1", "uniprot_id": "NR1D2_MOUSE", "id": "Q60674-1", "name": "Nuclear receptor subfamily 1 group D member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELNAGGVIAYIS--------------------------------SSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNCDANGNPKNADISSIDG---------------------VLKSDRTDCPVKTGKTSAPGMTKSHSGMTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNTQFSGHLQNDTLAEQHDQSALPAQEQLRPKSQLEQENIK-NTP--SDFAKEEVIGMVTRAHKDTFLYNQEHRENSSESMPPQRGERIPRNMEQYNLNQDHRG-----SGIHNHFPCSERQQHLSGQYKGRNIMHYPNGHAVCIANGHCMNFSSAYTQRVCDRIPVGGCSQTENRNSYLCNTGGRMHLVCP---MSKSPYVDPQKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLSSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKN---HPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14995-1", "uniprot_id": "NR1D2_HUMAN", "id": "Q14995-1", "name": "Nuclear receptor subfamily 1 group D member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVNAGGVIAYIS--------------------------------SSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDLANIEG---------------------ILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCG-----NGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENKNSYLCNTGGRMHLVCP---MSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKN---HPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P45447-1", "uniprot_id": "E78C_DROME", "id": "P45447-1", "name": "Ecdysone-induced protein 78C", "aln": "MDVYQIELEEQAQIRSKLLVETCVKHSSSEQQQLQVKQEDLIKDFTRDEEEQPSEEEAEEEDNEEDEEEEGEEEEEDEDEEALLPVVNFNANSDFNLHFFDTPEDSSTQGAYSEANSLESEQEEEKQTQQHQQQKQHHRDLEDCLSAIEADPLQLLHCDDFYRTSALAESVAASLSPQQQQQRQHTHQQQQQQQQQQQHPGQQQHQLNCTLSNGGGALYTISSVHQFGPASNHNTSSSSPSSSAAHSSPDSGCSSASSSGSSRSCGSSSASSSSSAVSSTISSGRSSNNSVVNPAATSSSVAHLNKEQQQQPLPTTQLQQQQQHQQQLQHPQQQQSFGLADSSSSNGSSNNNNGVSSKS--FVPCKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYR-CLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSRELNGAAASSAAAGAPASLNVDDSTSSTLHPSHLQ-------QQQQQHLLQQQQQQQHQPQLQQHHQLQQQPHVSGVRVKTPSTPQTPQMCSIASSPSELGGCNSANNNNNNNNNSSSGNASGGSGVSVGVVVVGGHQQLVGGSMVGMAGMGTDAHQVGMCHDGLAGTANELTVYDVIMCVSQAHRLNCSYTEELTRELMRRPVTVPQNGIASTVAESLEFQKIWLWQQFSARVTPGVQRIVEFAKRVPGFCDFTQDDQLILIKLGFFEVWLTHVARLIN--EATLTLDDGAYLTRQQLEILYDSDFVNALLNFANTLNAYGLSDTEIGLFSAMVLLASDRAGLSEPKVIGRARELVAEALRVQILRSRAGSPQALQLMPALEAKIPELRSLGAKHFSHLDWLRMNWTKLRLPPLFAEIFDIPKADDEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**.: ** *:**:.*. ** *..:..* .: **::.*. .*.*. .* ... .:: :: : : :: :. :....: * ::.:.*::. * .: ****** ***:**** :*************::*:*: **:: :* ::*:****** ********.*****:**:**:***.:: .** : .. ..** * * * : : *:*:: : * .:. : : *: .: .* * : * * .. * . * :: * *:. * .*: . :*:* * .:.* : :.:. . :. . . . . .. * * :. * ::.: . . . :*::** .**.*:.:******:*** *::*.**: *:* * *** :.:.* *:: * *:*: .* : ::*. : .*::.::::*::.**. *** *:.**:*:**:::**:*:.: : : :* : .***. *::. *: .::. * *:*:****. * ..* :::: ", "identical_positions": 171, "similar_positions": 205, "identity": "19.57%" }, { "cls_id": "homologset.agr.FB:FBgn0004867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25444-1", "uniprot_id": "RS2_MOUSE", "id": "P25444-1", "name": "Small ribosomal subunit protein uS5", "aln": "MADDAGAAGGPGGPGGPGLGGRGGFRGGFGSGLRGRGRGRGRGRGRGRGARG-GKAEDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27952-1", "uniprot_id": "RS2_RAT", "id": "P27952-1", "name": "Small ribosomal subunit protein uS5", "aln": "MADDAGAAGGPGGPGGPGLGGRGGFRGGFGSGLRGRGRGRGRGRGRGRGARG-GKAEDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15880-1", "uniprot_id": "RS2_HUMAN", "id": "P15880-1", "name": "Small ribosomal subunit protein uS5", "aln": "MADDAGAAGGPGGPGGPGMGNRGGFRGGFGSGIRGRGRGRGRGRGRGRGARG-GKAEDKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZAS1-1", "uniprot_id": "D3ZAS1_RAT", "id": "D3ZAS1-1", "name": "Small ribosomal subunit protein uS5", "aln": "MADDACAAGGPGGPGGPGLGGRGGFGGGFGSGLRGCGRGRGRGGGRGHGARG-GKAEDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPLKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAYVAIGDYKGHVGLGVKCSKEVATAIQGAIILAKLS--PVRRGYWGNKIGKPHTVRCKVTGRCGSVLVDLIPAPRGTGIVSALVPKKLLMMAGIEDCYTSARGCTATLGNFAKATFDAISKTYNYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31009-1", "uniprot_id": "RS2_DROME", "id": "P31009-1", "name": "Small ribosomal subunit protein uS5", "aln": "MADEAPARSG--------------FRGGFGS--RG-GRG-GRGRGRGRWARGRGKEDSKEWVPVTKLGRLVREGKIKSLEEIYLYSLPIKEFEIIDFFLGSSLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDNNGHIGLGVKCSKEVATAIRGAIILAKLSVVPVRRGYWGNKIGKPHTVPCKVTGKCGSVSVRLIPAPRGTGIVSAPVPKKLLTMAGIEDCYTSARGSTGTLGNFAKATYAAIAKTYAYLTPDLWKEMPLGSTPYQAYSDFLSKPTPRLHADA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25443-1", "uniprot_id": "RS2_YEAST", "id": "P25443-1", "name": "Small ribosomal subunit protein uS5", "aln": "MSAPEAQQQK---------------RGGFGG--------RNRGRPNRRGPRN---TEEKGWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLLPG-LQDEVMNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIPIRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPAVKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAIGNTYGFLTPNLWAEQPLPVSPLDIYSDEASAQKKRF-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ****. .** . : .*. :.* *:*********: **.::***:*.***:** :*** :* . *:***::* **************** *.:** :**:***:* :**** **:..**:**** *:******.::*:**:: *.**:**** * *******:***:: . **** :**::* **.:.* * ** * **:: **.:** :***:** * : :* : ::* *. ", "identical_positions": 133, "similar_positions": 64, "identity": "45.24%" }, { "cls_id": "homologset.agr.FB:FBgn0004868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50399-1", "uniprot_id": "GDIB_RAT", "id": "P50399-1", "name": "Rab GDP dissociation inhibitor beta", "aln": "-----MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPAS----MGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG--KVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQ-VIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61598-1", "uniprot_id": "GDIB_MOUSE", "id": "Q61598-1", "name": "Rab GDP dissociation inhibitor beta", "aln": "-----MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPAS----MGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG--KVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQ-VIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50395-1", "uniprot_id": "GDIB_HUMAN", "id": "P50395-1", "name": "Rab GDP dissociation inhibitor beta", "aln": "-----MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG--KVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQ-VIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50396-1", "uniprot_id": "GDIA_MOUSE", "id": "P50396-1", "name": "Rab GDP dissociation inhibitor alpha", "aln": "-----MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILEGPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG--KVVGVKSEGEVARCKQLICDPSYIPDRVQKAGQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEADQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50398-1", "uniprot_id": "GDIA_RAT", "id": "P50398-1", "name": "Rab GDP dissociation inhibitor alpha", "aln": "-----MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG--KVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEADQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31150-1", "uniprot_id": "GDIA_HUMAN", "id": "P31150-1", "name": "Rab GDP dissociation inhibitor alpha", "aln": "-----MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPES----MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG--KVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQ-VIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLB7-1", "uniprot_id": "Q9VLB7_DROME", "id": "Q9VLB7-1", "name": "Rab GDP dissociation inhibitor", "aln": "-----MNEEYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASITPLEELFQRYGLE-PPGER----FGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYKGGKIAKVPVDQKEALASDLMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGLDKNTQDFTGHALALFRDDEYLNEPAVNTIRRIKLYSDSLARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDKPIDEIVLGEGG-KVVGVRSGEEVAKCKQVYCDPSYVPEKVRKRGK-VIRCICILDHPVASTKDGLSTQIIIPQKQVGRKSDIYVSLVSSTHQVAAKGWFVGMVSTTVETENPEVEIKPGLDLLEPIAQKFVTISDYLEPIDDGSESQIFISESYDATTHFETTCLDVLNIFKRGTGETFDFSKIKHELGDEEQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39958-1", "uniprot_id": "GDI1_YEAST", "id": "P39958-1", "name": "Rab GDP-dissociation inhibitor", "aln": "MDQETIDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVT-LSQLYEKFKQNPISKEERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDVTRYVDFKQVSGSYVFKQGKIYKVPANEIEAISSPLMGIFEKRRMKKFLEWISSYKEDDLSTHQGLDLDKNTMDEVYYKFGLGNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQSVARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDTPIDEVLYKKDTGKFEGVKTKLGTFKAPLVIADPTYFPEKCKSTGQRVIRAICILNHPVPNTSNADSLQIIIPQSQLGRKSDIYVAIVSDAHNVCSKGHYLAIISTIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDGSKDNIYLSRSYDASSHFESMTDDVKDIYFRVTGHPLVLKQRQEQEKQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :**.******:.******::**.******:*:: :****::*:* *.:*:::: . :*:.****************:*.::*:.* ****::** .**:*:* *** *** : **::* ***:*****:::** :: .: *.* * :..* . .* :* **.*.:.. :* **::**: *:**::*. :..** **.:*:***********:***********************:.*::::: :. *. **:: :. : .**:*. :: .. *: *** ****.**: .*.:. * ******.*:.*******.::* :*:*.::* ::.: ** :** .*. *:.*.:.** ** :**: *:: * : * ..::: * :***::***: *: :*: * :* : :.: :.: : ", "identical_positions": 201, "similar_positions": 153, "identity": "43.79%" }, { "cls_id": "homologset.agr.FB:FBgn0004872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTP9-1", "uniprot_id": "D3ZTP9_RAT", "id": "D3ZTP9-1", "name": "Piwi-like protein 1", "aln": "MTGRARARARGRAR-----------GQETVQHVGAAAQSQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSK-SQELQISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNH--RLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKP--LDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKA-IMIEVDDRTEAYLRALQQKVTS----DTQI---------VVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEG-MTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGY---NPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMB7-1", "uniprot_id": "PIWL1_MOUSE", "id": "Q9JMB7-1", "name": "Piwi-like protein 1", "aln": "MTGRARARARGRAR-----------GQETVQHVGAAA-SQQPGYIPPRPQQSPTEGDLVGRGRQRGMVVGATSK-SQELQISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLPKRLQHKVTEVFSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNH--RLVIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDWGLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKP--LDNWLLIYTRRNYEAANSLIQNLFKVTPAMGIQMKKA-IMIEVDDRTEAYLRALQQKVTS----DTQI---------VVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGIDCYHDTTAGRRSIAGFVASINEG-MTRWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPSRVIVYRDGVGDGQLKTLVNYEVPQFLDCLKSVGRGY---NPRLTVIVVKKRVNARFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96J94-1", "uniprot_id": "PIWL1_HUMAN", "id": "Q96J94-1", "name": "Piwi-like protein 1", "aln": "MTGRARARARGRAR-----------GQETAQLVGSTA-SQQPGYIQPRPQPPPAEGELFGRGRQRG-TAGGTAK-SQGLQISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAFDGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPNDPIDIPSH--RLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDYNPQFADWSKETRGAPLISVKP--LDNWLLIYTRRNYEAANSLIQNLFKVTPAMGMQMRKA-IMIEVDDRTEAYLRVLQQKVTA----DTQI---------VVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTAGRRSIAGFVASINEG-MTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGY---NPRLTVIVVKKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVX0-1", "uniprot_id": "PIWL1_DANRE", "id": "Q8UVX0-1", "name": "Piwi-like protein 1", "aln": "MTGRARARSRGRGR-----------GQEPAAPGAQPPVSQEAAKP---VVSTPSEGQLVGRGRQKP-APGAMSE-EAMLQISAGFQQVKIGERGGR-RRDFHDSGVHTRQLMEHVKESKTGVSGTAIELRANFMRLLSRPMWALYQYHVDYKPPMESRRLRSALLFQHEETLGKAHTFDGAILFLPNKLRNAETVLCSETRNGEKVEITVTLTNELPPSSPVCLQFYNILFRRILRILNMQQIGRHYYNPDDPFNIPQH--RLTIWPGFMTTILQYESSIMLCSDVSHKVLRSETVLDFMYSLRQQCGDQRFPEACTKELVGLIILTKYNNKTYRIDDIAWDHTPNNTFKKGD-TEISFKNYFKSQYGLDITDGNQVLLVSHVKRLGPSGRPPPGPAMLVPEFCYLTGLTDKMRADFNIMKDLASHTRLSPEQREGRINRLISNINRNGDVQNELTTWGLSFENKLLSLNGRVLPSERIIQGGRAFEYNPWTADWSKEMRGLPLISCMS--LDNWLMFYTRRNADVAQSLLQTLNKVSGPMGIRMQRA-VMIEYEDRQESLLRALQQNVAR----ETQM---------VVVILPTNRKDKYDCVKKYLCVDCPTPSQCVVSRTISKPQALMTVATKIALQMNCKMGGELWSVEIPLRQLMIVGIDCYHDTAAGKRSIGAMVASLNQG-MSRWFSKCVLQNRGQEIIDALKGSLQGALKAYLKYNNSLPSRIIVYRDGVGDGMLQSVVDYEVPQIMQSIKTMGQDY---EPKLSVVVVKKRISSRFFARIDGKIANPPPGTVIDTEVTRPEWYDFFIVSQAVRFGCVAPTHYNVVFDNSGLKPDHMQRLTYKLCHMYYNWQGIVRVPAPCQYAHKLAFLVGQSIHKEPNMNLDDFLYYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8CGT6-1", "uniprot_id": "PIWL4_MOUSE", "id": "Q8CGT6-1", "name": "Piwi-like protein 4", "aln": "MSGRARVRARGITT-----------GHSAREVGRSSR---------DLMVTSASPGDSEAGG-----GTSVISQ-PYELGVSSGDGGRTFMERRGKGRQDFEELGVCTREKLTHVKDCKTGSSGIPVRLVTNLFNLDLPQDWQLYQYHVTYSPDLASRRLRIALLYNHSILSDKAKAFDGASLFLSEKLDQKVTELTSETQRGETIKITLTLTSKLFPNSPVCIQFFNVIFRKILKNLSMYQIGRNFYKPSEPVEIPQY--KLSLWPGFAISVSHFESKLLFNADVNYKVLRNETVLDFMTDLCLRTGMSCFTEMCHKQLVGLVVLTRYNNKTYRIDDIDWSVKPTQAFQKRDGSEVTYVDYYKQQYDITLSDLNQPVLVSLLKRKR-NDNSEPQMVHLMPELCFLTGLSSQATSDFRLMKAVAEETRLSPVGRQQQLARLVDDIQRNPVARFELETWGLHFGS-QLSLTGRVVPSEKILLQDHTCQP-AFAADWSKDMRSCKVLSSQP--LNRWLIVCCNRAEHLIEAFLSCLRRVGGSMGFNVGYP-KIIKVDETPAAFLRAIQVHGDP----DVQL---------VMCILPSNQKNYYDSIKKYLSSDCPVPSQCVLTRTLNKQGTMLSVATKIAMQMTCKLGGELWSVEIPLKSLMVVGIDICRDALNKNVVVVGFVASINSR-ITRWFSRCVLQRTAADIADCLKVCMTGALNRWYRHNHDLPARIVVYRDGVGNGQLKAVLEYEVPQLLKSVTECGSDAR--SCRLSVVVVRKRCLLRLFASTDHTVQNPPLGTVVDSEATRPEWYDFYLISQTANRGTVSPTHYNVIYDDNALKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSVHKEPSLELANNLFYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G033-1", "uniprot_id": "PIWL4_RAT", "id": "Q4G033-1", "name": "Piwi-like protein 4", "aln": "MSGRARVRARGITT-----------GHSAREVERAPR---------DLMVTSVSPGDNEASS-----RTSVISQ-PHELGVSSGDGRRTLVEKRGNGRQDFVDLGVCTREKLTHVKDSKTGSSGIPVQLATNLFHLDLPQDWQLYQYHVTYSPDLASRRLRTALLYNHSILSDKAKAFDGTSLFLSEKLDHKVTELTSETQRGETVKITLTLTSELFPNSPMCIQFFNVIFRKIFKKLSMYQIGRNYYKPSEPVEIPQY--KLSLWPGFAISVSRFESKLLVNADVNYKVLRNETVLEFMTDLCLRTDMSCFTETCHKQLVGLIVLTRYNNKTYRIDDIDWSVKPTHAFQKRDGSETTYVDYYKQQYDITLSDLNQPVLVSLLKRRR-NDNSEPQMVHLIPELCFLTGLTSQATSDFRLMKAVAEETRLSPMGRQQQLARLADDIQRNQVTRFELETWGLHFGS-QLSLTGRVVPSEKILLQDHTCQP-AFAADWSKDMRSCKVLSSEP--LNTWLIVCCSRAEHLIESFLSCLRRVGGSTGFSVGHP-KIIKVDENPAAFLRAIQLHVNP----DVQL---------VMCILPSNQKNYYDSIKRYLSSDCPVPSQCVLTRTLNKQGMMLSVATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDICRDALSKDVAVVGFVASINSR-ITRWFSRCVLQRTAADIADCLKVCMTGALNKWYKHNHDLPARIIAYRDGVGNGQLKAVLEYEVPQLLSSVTECGSDAR--SCRLSVVVVRKRCLLRLFAESGHTLQNPPLGTVVDSEATRPEWYDFYLTSQTANRGTVSPTYYNVIYDDNALKPDHMQRLTFKLCHLYYNWQGVISVPAPCQYAHKLTFLVAQSIHKEPSLELANKLFYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3Z4-1", "uniprot_id": "PIWL4_HUMAN", "id": "Q7Z3Z4-1", "name": "Piwi-like protein 4", "aln": "MSGRARVKARGIAR-----------SPSATEVGRIQA---------SPLPRSVDLSNNEASSSNGFLGTSRIST-NDKYGISSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKTGSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDGAILFLSQKLEEKVTELSSETQRGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQH--KLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPMLVSLLKKKR-NDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGS-QISLTGRIVPSEKILMQDHICQP-VSAADWSKDIRTCKILNAQS--LNTWLILCSDRTEYVAESFLNCLRRVAGSMGFNVDYP-KIIKVQENPAAFVRAIQQYVDP----DVQL---------VMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKDALSKDVMVVGCVASVNPR-ITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNT---SSRLSVIVVRKKCMPRFFTEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7Z3Z3-1", "uniprot_id": "PIWL3_HUMAN", "id": "Q7Z3Z3-1", "name": "Piwi-like protein 3", "aln": "MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIG--GVFQDLVVNTRQDMKHVKDSKTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNSLLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQGRRMVKA-NSQGDWSREIRELPLLNAMP--LHSWLILYSRSSHREAMSLKGHLQSVTAPMGITMKPA-EMIEVDGDANSYIDTLRKYTRP----TLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCTKCPIPSQCVVKKTLEKVQAR-TIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIVNRQKSIAGFVASTNAE-LTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNN----FTLAFIVVKKRINTRFFLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKM1-1", "uniprot_id": "PIWI_DROME", "id": "Q9VKM1-1", "name": "Protein piwi", "aln": "---MADDQGRGRRR------------PLNEDDSSTSR--------------GSGDGPRVKVFRGSSSGDPRADPRIEASRERRALEEAPRREGGPTERKPWGDQYDYLNTRPAELVS-KKGTDGVPVMLQTNFFRLKTKPEWRIVHYHVEFEPSIENPRVRMGVLSNHANLLGSGYLFDGLQLFTTRKFEQEITVLSGKSKLDIEYKISIKFVGFISCAEPRFLQVLNLILRRSMKGLNLELVGRNLFDPRAKIEIREF--KMELWPGYETSIRQHEKDILLGTEITHKVMRTETIYDIMRRCSHNP--ARHQDEVRVNVLDLIVLTDYNNRTYRINDVDFGQTPKSTF-SCKGRDISFVEYYLTKYNIRIRDHNQPLLISK-NRDKALKTNASELVVLIPELCRVTGLNAEMRSNFQLMRAMSSYTRMNPKQRTDRLRAFNHRLQNTPESVKVLRDWNMELDKNVTEVQGRIIGQQNIVFHNGKVPA-GENADWQRHFRDQRMLTTPSDGLDRWAVIAPQRNSHELRTLLDSLYRAASGMGLRIRSPQEFIIYDDRTGTYVRAMDDCVRSDPKL-------------ILCLVPNDNAERYSSIKKRGYVDRAVPTQVVTLKTT-KNRSLMSIATKIAIQLNCKLGYTPWMIELPLSGLMTIGFDIAKSTRDRKRAYGALIASMDLQQNSTYFSTVTECSAFDVLANTLWPMIAKALRQYQHEHRKLPSRIVFYRDGVSSGSLKQLFEFEVKDIIEKLKTEYARVQLSPPQLAYIVVTRSMNTRFFLNG----QNPPPGTIVDDVITLPERYDFYLVSQQVRQGTVSPTSYNVLYSSMGLSPEKMQKLTYKMCHLYYNWSGTTRVPAVCQYAKKLATLVGTNLHSIPQNALEKKFYYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.** . * : : . .: . *.* .* : * :* :.: * :*:: : * : .:* :* .* . *** *: .. : . . . :: .::: : : .* :: *:::*: :: :.: :**: : .:: . : :* *: :: .* .: . :::.:*::* ** ::: . : :::. ::** ***:** ::*: : .* :* . . . :: :*: :: : :* :*:* . *:*::* :***. : :: ::: :: **:.* * : : :: * *.: : . .. **:: .* .**.:. * ::. . *. * :. :: * . *: : . :* : : : .: :: ::..: *..:*: . . *:* * :* * ::.**** *:.**:* * :: : * :*:* :. . :** : : ::* : . * : ** : . :* :: ** **..* *: :.:.*. .: : *: :** : *:* ** **::* * * ***:: ** . * *:** ***::. .*.*: :*:**: :**:*** * *** *:**:**: **. .:* *. * ::**", "identical_positions": 151, "similar_positions": 242, "identity": "16.82%" }, { "cls_id": "homologset.agr.FB:FBgn0004875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TM6-1", "uniprot_id": "R3HD2_MOUSE", "id": "Q80TM6-1", "name": "R3H domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEDVEKEGEENGLRQETQRRTSSHGHARKRAKSNS-KLKLVR-----------------------SLAVCEESS-TPFVDGPLDTQDIIQLHIS-CPSDKEEEKSTKDVSEKED-------------------------------------------------------------KDKSKEKVPR----KMLSRDS------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILDFINDNNNQFK-KFPQMTSYHRMLLHRVAAYFGMDHNVD-QTGKAVIINKTSSTRIPEQR--FSEHIKDEKNTEFQQRFILKRDDASMDRDDNQ--MRVPLQDGRRSKSIEEREEEYQRVRERIFAR----------------------------------------------------------------------------------------------ETGQNGYLNDIRLSKEA---------------------------------------------------FSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELKSLE-PRPWSSTDSDGSVRSMRPPVTKASSFS----------------GISILTRGD---------------SIGSSK----------------GGSAGRLSR-----PGMALG-----APEVCNQVTSPQSVR---GLLPCTAQQQQQQQQQQQQ-LPALPP-----TPQHQPPLNNHMISQPVPALQPSPQPVQFSPSSCPQV-LLPVSPPQQYNMAEDLSN---------------------------------------------------PFGQMSLSRQG-------STEAADP-SSALFQPPLISQHPQQASFIMA--------------------SAGQPLPTSNYSTSSHAPPTQQVLP--------PQGYMQ--PPQQIQVSYYPPGQYPNSN-QQYRPLSHPVAYSPQRGQQLPQASQQPGLQPMMSNQQQTAYQGMLGVQQP-QNQGLLSNQRS-SMGGQMQG-------------------------------------------------LVVQYTPLPSYQVPVGSDSQN--------------------VVQPSFQQPMLVPASQSVQGGLPTGGVPVYYSMIPPAQQN-------------------GTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMS-QQYSGVS---------------------------------------PSGPGVVVMQLNVPNGPQAPQNPSMVQWSHCKYYSVEQRGQKPGDLYSPDGSPQANAQMGSSPVTSPTQSPAPSPVTSLSNVCTGLSPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLP-------GAGGGDNSG-------------------------------------TAENGRHPDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLX2-1", "uniprot_id": "A0A8I5ZLX2_RAT", "id": "A0A8I5ZLX2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEEVEKEGEENGLRQETQRRTSSHGHARKRAKSNS-KLKLVR-----------------------SLAVCEECS-TPFVDGPLDTQDIIQLHIS-CPSDKEEEKSTKDVSEKDD-------------------------------------------------------------KDKSKEKVPR----KMLSRDS------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILDFISDNNNQFK-KFPQMTSYHRMLLHRVAAYFGMDHNVD-QTGKAVIINKTSSTRIPEQR--FSEHIKDEKNTEFQQRFILKRDDASMDREEN--------------------------------------------------------------------------------------------------------------------------------QAGQNGYLNDIRLSKEA---------------------------------------------------FSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELKSLE-PRPWSSTDSDGSVRSMRPPVTKASSFS----------------GISILTRGD---------------SIGSSK----------------GGSAGRLSR-----PGMTLG-----APEVCNQVTSPQSVR---GLLPCTVQQQQQQQQQQQQ-LPALPP-----VPQQQPPLNNHMISQPVPALQPSPQPVQFSPSSCPQV-LLPVSPPQQYNMAEDLSN---------------------------------------------------PFGQMSLSRQG-------STEAADP-SSALFQSPLISQHPQQASFIMA--------------------SAGQPLPTSNYSTSSHAPPTQQVLP--------PQGYMQ--PPQQIQVSYYPPGQYPNSN-QQYRPLSHPVAYSPQRGQQLPQASQQPGLQPMMSSQQQTAYQGMLGVQQP-QNQGLLSNQRSNSMGGQMQG-------------------------------------------------LVVQYTPLPSYQVPVGSESQN--------------------VVQPPFQQPMLVPASQSVQGGLPAGGVPVYYSVIPPAQQN-------------------GTSPSVGFLQPPGSEQYQMPQSPAPCSPPQIP-QQYSGVS---------------------------------------PSGPGVVVMQLNVPNGPQAPQNPSMVQWGHCKYYSVDQRGQKPGDLYSPDGDPQTNAQMGSSPVTSPTQSPAPSPVTSLSSVCTGLSPLPVLTPFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLP-------GAGGGDNSG-------------------------------------TAENGRHADLAALYTIVAVFPSPLAAHNASLRLNNSVSRFKLRVAKKNYDLRILERASSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K5-1", "uniprot_id": "R3HD2_HUMAN", "id": "Q9Y2K5-1", "name": "R3H domain-containing protein 2", "aln": "----------------------------------------------------------------------------------------------------MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEEIEKECEDTSLRQETQRRTSNHGHARKRAKSNS-KLKLVR-----------------------SLAVCEESS-TPFADGPLETQDIIQLHIS-CPSDKEEEKSTKDVSEKED-------------------------------------------------------------KDKNKEKIPR----KMLSRDS------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLVNTLKKNPRDRMMLLKLEQEILEFINDNNNQFK-KFPQMTSYHRMLLHRVAAYFGMDHNVD-QTGKAVIINKTSNTRIPEQR--FSEHIKDEKNTEFQQRFILKRDDASMDRDDN--------------------------------------------------------------------------------------------------------------------------------QTGQNGYLNDIRLSKEA---------------------------------------------------FSSSSHKRRQIFRGNREGLSRTSSSRQSSTDSELKSLE-PRPWSSTDSDGSVRSMRPPVTKASSFS----------------GISILTRGD---------------SIGSSK----------------GGSAGRISR-----PGMALG-----APEVCNQVTSSQSVR---GLLPCTAQQQQQQQQQQ---LPALPP-----TPQQQPPLNNHMISQ-----------------------------------ADDLSN---------------------------------------------------PFGQMSLSRQG-------STEAADP-SAALFQTPLISQHPQQTSFIMA--------------------STGQPLPTSNYSTSSHAPPTQQVLP--------PQGYMQ--PPQQIQVSYYPPGQYPNSN-QQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQP-QNQGLLSSQRS-SMGGQMQG-------------------------------------------------LVVQYTPLPSYQVPVGSDSQN--------------------VVQPPFQQPMLVPVSQSVQGGLPAAGVPVYYSMIPPAQQN-------------------GTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMP-QQYSGVS---------------------------------------PSGPGVVVMQLNVPNGPQPPQNPSMVQWSHCKYYSMDQRGQKPGDLYSPDSSPQANTQMSSSPVTSPTQSPAPSPVTSLSSVCTGLSPLPVLTQFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAMSGAKIQWLKDAQGLP-------GGGGGDNSG-------------------------------------TAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GEX2-1", "uniprot_id": "A0A8I6GEX2_RAT", "id": "A0A8I6GEX2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MRMSDIVIIKDETETMKDLEAEMRDTTRVENLIKSENYGKISAEKNEHCIDNNIDLQRPPQSFGQTGKRSKSSS-KLKLVR-----------------------SLAVCEESPPPPAAEIPQETQEKIQIQLT-QSFEKEE-KPSKDETDKE----------------------------------------------------------------KASDKLPR----KMLSRDS------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLVNTLKNNPRDRMMLLKLEQEILDFIGNNESPRK-KFPPMTSYHRMLLHRVAAYFGLDHNVD-QSGKSVIVNKTSNTRIPDQK--FNEHIKDDRGEDFQKRYILKRDNSSFDKDDSQ--MRIRLKDDRRSKSIEEREEEYQRARDRIFSQDS--------------------------------------------------------------------------------------------LCSQENYIIDKRIPDED---------------------------------------------------TIG-TQQRRQIFRVNKDASGRSTNSHQSSTENELKYSE-PRPWSSTDSDSSLRNLKPAVTKASSFS----------------GISVLTRGD---------------SSGSSKSIGRLSKTGSESSGSVGSSTGSLSHTQQPLPGSALSQSSHGAPVIYPAASNHSSLSFDGGLNGQGASPSTSFLLLPLE-ATGIPPGSILINPQTGQPFINPDGSPVVYNPPMTQQSVRTQVPGPPQP-PLPPPPPQQPAASHMFSQ----------------------------------------------DNLGSQFSHMSLARQP-------SADGSDP-HATMFQSTVVLQSPQQSGYIVTTAPP-HPPPPPPPPPPPPSLPPGQSVPTASFS--GHPVS-QPVLQ--------QQGFLPQ-PSPQMPACYCAPGHYHSSQ-PQYRPIPS-VHHSSHLNQPLPQPAQHTGYQ-VMPNQQQ-NYQGIVGVQSP-QSQSLMGGQPN-STGPHIQG-------------------------------------------------VVIPYPSVPSYQVSLPQGSQG--------------------IAHQTYQQPVVFPN-QSNQGSLPTAGMPVYYSVIPPGQQS-------------------NLSSAVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCAALPQ-------------------------------------QPPGGGMVMMQLNLPNNAPS-RAHSPPQWKQNKYHCDHQRGQKCMEVSHMDSIVQHSPQLSS-PILSPVQSPAPAQLSALKTTRPSGPPLSIVSQFARPFVPGQGDARYPLLGQPLQYSP---PTLLHGHIPH--QQGQSGSRHGNRGRRQAKKAASTDLGAGEAVVGKVLEITELPDGITRMEAEKLFGELFKIGAKIRWLRDPQSQPQLRRHPLCCGSGDNTV-------------------------------------NPERSKPSDLASTYTVLATFPSISAAQSALKKQIHSVNKFKLRMSKKHYDFHILERASSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9Q2-1", "uniprot_id": "E9Q9Q2_MOUSE", "id": "E9Q9Q2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MRMSDIVIIKDETETMKDLEAEMRDTTRVENLIKSENYGKISAEKNEHCIDNNIDLQRPPQSFGQTGKRSKSSS-KLKLVR-----------------------SLAVCEESPPPPAAEISQETQEKIQIQLT-QSFEKEE-KPSKDETDKE----------------------------------------------------------------KASDKLPR----KMLSRDS------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLVNTLKNNPRDRMMLLKLEQEILDFIGNNESPRK-KFPPMTSYHRMLLHRVAAYFGLDHNVD-QSGKSVIVNKTSNTRIPDQK--FNEHIKDDRGEDFQKRYILKRDNSSFDKDDSQ--MRIRLKDDRRSKSIEEREEEYQRARDRIFSQDS--------------------------------------------------------------------------------------------LCSQENYIIDKRIQDED---------------------------------------------------TIG-TQQRRQIFRVNKDASGRSTNSHQSSTENELKYSE-PRPWSSTDSDSSLRNLKPAVTKASSFS----------------GISVLTRGD---------------SSGSSKSIGRLSKTGSESSGSVGSSTGSLSHTQQPLPGSALSQSSHGAPVIYPAASNHSSLSFDGGLSGQGASPSTSFLLLPLE-ATGIPPGSILINPQTGQPFLNPDGSPVVYNPPMTQQPVRTQVPGPPQP-PLPPPPPQQPAASHMFSQPVGPLQSSSQPVQCSPAPYPSPLLPV------------SPTQQYSVDNLGAQFSHMSLARQP-------SADGSDP-HATMFQSTVVLQSPQQSGYIVTTAPP-HPPPPPPPPPPPPSLPPGQSVPTASFSASGHPVS-QPVLQ--------QQGFLPQ-PSPQMPACYCAPGHYHSSQ-PQYRPIPS-VHHSSHLNQPLPQPAQHTGYQ-VMPNQQQ-NYQGIVGVQSP-QSQSLMGGQPN-STGPHIQG-------------------------------------------------VVIPYPSVPSYQVSLPQGSQG--------------------IAHQTYQQPVVFPN-QSNQGSLPTTGMPVYYSVIPPGQQS-------------------NLSSAVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCAAVPQ-------------------------------------QPPGGGMVMMQLNLPNNPQS-RTHSPPQWKQNKHYCDHQRGQKCMDFSNMDNIVQPSPQLSS-PILSPVQSPAPAQLSTLKTIRPSGPPLSIMSQFARPFVPGQGDARYPLLGQPLQYNP---PTLLHGHIPH--QQGQSGSRHGNRGRRQAKKAASTDLGAGEAVVGKVLEITELPDGITRVEAEKLFGELFKIGAKIRWLRDPQSQPQLRRHALCCGSGDNTV-------------------------------------NPEHSKPSDLASTYTVLATFPSISAAQSALKKQIHSVNKFKLRMSKKHYDFHILERASSQ------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15032-1", "uniprot_id": "R3HD1_HUMAN", "id": "Q15032-1", "name": "R3H domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------MRMSDTVTVKDETATMKDLEAEVKDTTRVENLIKSENYGKILVEKNEHCIENNIDLQRPLQSFGQTGKRSKSSS-KLKLVR-----------------------SLAVCEESPPPPAPEISQENQEKIQIQLT-QSFEKEE-KPSKDEAEKE----------------------------------------------------------------KASDKLPR----KMLSRDS------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLVNTLKNNPRDRMMLLKLEQEILDFIGNNESPRK-KFPPMTSYHRMLLHRVAAYFGLDHNVD-QSGKSVIVNKTSNTRIPDQK--FNEHIKDDKGEDFQKRYILKRDNSSFDKDDNQ--MRIRLKDDRRSKSIEEREEEYQRARDRIFSQDS--------------------------------------------------------------------------------------------LCSQENYIIDKRLQDED---------------------------------------------------ASS-TQQRRQIFRVNKDASGRSTNSHQSSTENELKYSE-PRPWSSTDSDSSLRNLKPAVTKASSFS----------------GISVLTRGD---------------SSGSSKSIGRLSKTGSESSGSVGSSTGSLSHIQQPLPGTALSQSSHGAPVVYPTVSTHSSLSFDGGLNGQVASPSTSFFLLPLE-AAGIPPGSILINPQTGQPFINPDGSPVVYNPPMTQQPVRSQVPGPPQP-PLPAPP-QQPAANHIFSQ----------------------------------------------DNLGSQFSHMSLARQP-------SADGSDP-HAAMFQSTVVLQSPQQSGYIMTAAPPPHPPPPPPPPPPPPPLPPGQPVPTAGYPASGHPVS-QPVLQ--------QQGYIQQ-PSPQMPACYCAPGHYHSSQ-PQYRPVPS-VHYNSHLNQPLPQPAQQTGYQ-VIPNQQQ-NYQGIVGVQQP-QSQSLVSGQPN-SIGNQIQG-------------------------------------------------VVIPYTSVPTYQVSLPQGSQG--------------------IPHQTYQQPVMFPN-QSNQGSMPTTGMPVYYSVIPPGQQN-------------------NLSSSVGYLQHPGSEQVQFPRTTSPCSSQQLQGHQCTAGPP-------------------------------------PPPGGGMVMMQLSVPNNPQS-CAHSPPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQLSS-PIISPAQSPAPAQLSTLKTVRPSGPPLSIMPQFSRPFVPGQGDSRYPLLGQPLQYNP---PAVLHGHIPN--QQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITRMEAEKLFGELFKIGAKIRWLRDPQSQP--RRHPLCCGSGDNTA-------------------------------------NPERSKPSDLASTYTVLATFPSISAAQNALKKQINSVNKFKLRTSKKHYDFHILERASSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JVX9-1", "uniprot_id": "A0A0G2JVX9_RAT", "id": "A0A0G2JVX9-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MSEQ--GELTPTILEEGRTEPESA-PENGILKSESLDEE--EK--------LELQRRLAAQNQERRKSKSGAGKGKLTR-----------------------SLAVCEESSARPGGESHQD-QESIHLQLSSFPSLQEEDKSRKDDSEREKE------------------------------------------------------------KDKNREKLSERPKIRMLSKDC------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLINTLKNNSRDRMILLKMEQEMIDFIADSNNHYK-KFPQMSSYQRMLVHRVAAYFGLDHNVD-QTGKSVIINKTSSTRIPEQR--FCEHLKDEKSEESQKRFILKRDNSSIDKEDNQQNRMHPFRDDRRSKSIEEREEEYQRVRERIFAHDS--------------------------------------------------------------------------------------------VCSQESLFLDNSRLQEDM-------------------------------------------------HICNETYKKRQLFRAHRDSSGRTSGSRQSSSETELRWPDHQRAWSSTDSDSSNRNLKPTMTKTASFG----------------GITVLTRGD---------------STSSTRSAGKLSKTGSESSSS-AGSSGSLSRTHPPLQSTALTSSVAAGSPGCMAYSEN-------GMGGQVPPSSTSYILLPLESATGIPPGSILLNPHTGQPFVNPDGTPAIYNPPGSQQTLRGTVSGQPQQ-PPPQQPSPQPQQQVQASQPQMTGPLVTQSVQGLQPSSQSVQYPAVSFPPQHLLPVSPTQHFPLREEMAAQFSQLSMSRQS-------SGDTPEPPSGPVYPASLM-QAAQPPSYVIT--------------------SAGQQLSTGGFSDSGPPIS-QQVLQAPPS----PQGFVQQPPPAQMSVYYYPSGQYPTSTTQQYRPLAS-VQYSAQRSQQIPQTAQQAGYQPVLSGQQS--FQGLMGVQQSAHSQGVMSSQQG----APVHG-------------------------------------------------VMVSYPTMSSYQVPMTQGSQA--------------------VPQQTYQPPIMLPS-QTGQGSLPATGMPVYCNITPPSPQN-------------------NLR-----LMGPHCPSSTVPVMSASCR--------------------------------------------------------------------------------------------TNCGSMNNAGWPVKF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCB4-1", "uniprot_id": "ARP21_MOUSE", "id": "Q9DCB4-1", "name": "cAMP-regulated phosphoprotein 21", "aln": "----------------------------------------------------------------------------------------------------MSEQ--GGLTPTILEEGQTEPESA-PENGILKSESLDEE--EK--------LELQRRLAAQNQERRKSKSGAGKGKLTR-----------------------SLAVCEESSARSGGESHQD-QESIHLQLSSFPSLQEEDKSRKDDSEREKE------------------------------------------------------------KDKNREKLSERPKIRMLSKDC------------------------------------------------------------------------------------SQEYTDSTGIDLHGFLINTLKNNSRDRMILLKMEQEMIDFIADSNNHYK-KFPQMSSYQRMLVHRVAAYFGLDHNVD-QTGKSVIINKTSSTRIPEQR--FCEHLKDEKSEESQKRFILKRDNSSIDKEDNQ-NRMHPFRDDRRSKSIEEREEEYQRVRERIFAHDS--------------------------------------------------------------------------------------------VCSQESLFLDNSRLQEDM-------------------------------------------------HICNETYKKRQLFRAHRDSSGRTSGSRQSSSETELRWPDHQRAWSSTDSDSSNRNLKPTMTKTASFG----------------GITVLTRGD---------------STSSTRSAGKLSKTGSESSSS-AGSSGSLSRTHP--QSTALTSSVAAGSPGCMAYSEN-------GMGGQVPPSSTSYILLPLESATGIPPGSILLNPHTGQPFVNPDGTPAIYNPPGSQQTLRGTVGGQPQQ-PPQQQPSPQPQQQVQASQPQMAGPLVTQ-----------------------------------REELAAQFSQLSMSRQS-------SGDTPEPPSGTVYPASLLPQTAQPQSYVIT--------------------SAGQQLSTGGFSDSGPPIS-QQVLQAPPS----PQGFVQQPPPAQMSVYYYPSGQYPTSTSQQYRPLAS-VQYSAQRSQQIPQTTQQAGYQPVLSGQQG--FQGMMGVQQSAHSQGVMSSQQG----APVHG-------------------------------------------------VMVSYPTMSSYQVPMTQGSQA--------------------VPQQTYQPPIMLPS-QAGQGSLPATGMPVYCNVTPPNPQN-------------------NLR-----LMGPHCPSSTVPVMSASCR--------------------------------------------------------------------------------------------TNCGNVSNAGWQVKF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBL0-1", "uniprot_id": "ARP21_HUMAN", "id": "Q9UBL0-1", "name": "cAMP-regulated phosphoprotein 21", "aln": "----------------------------------------------------------------------------------------------------MSEQ--GDLNQAIAEEGGTEQETATPENGIVKSESLDEE--EK--------LELQRRLEAQNQERRKSKSGAGKGKLTR-----------------------SLAVCEESSARPGGESLQD-QESIHLQLSSFSSLQEEDKSRKDDSEREKE------------------------------------------------------------KDKNKDKTSEKPKIRMLSKDC------------------------------------------------------------------------------------SQEYTDSTGIDLHEFLINTLKNNSRDRMILLKMEQEIIDFIADNNNHYK-KFPQMSSYQRMLVHRVAAYFGLDHNVD-QTGKSVIINKTSSTRIPEQR--FCEHLKDEKGEESQKRFILKRDNSSIDKEDNQQNRMHPFRDDRRSKSIEEREEEYQRVRERIFAHDS--------------------------------------------------------------------------------------------VCSQESLFVENSRLLEDS-------------------------------------------------NICNETYKKRQLFRGNRDGSGRTSGSRQSSSENELKWSDHQRAWSSTDSDSSNRNLKPAMTKTASFG----------------GITVLTRGD---------------STSSTRSTGKLSKAGSESSSS-AGSSGSLSRTHPPLQSTPLVSGVAAGSPGCVPYPEN-------GIGGQVAPSSTSYILLPLEAATGIPPGSILLNPHTGQPFVNPDGTPAIYNPPTSQQPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMAGPLVTQ-----------------------------------RDDVATQFGQMTLSRQS-------SGETPEPPSGPVYPSSLMPQPAQQPSYVIA--------------------STGQQLPTGGFSGSGPPIS-QQVLQPPPS----PQGFVQQPPPAQMPVYYYPSGQYPTSTTQQYRPMAP-VQYNAQRSQQMPQAAQQAGYQPVLSGQQG--FQGLIGVQQPPQSQNVINNQQG----TPVQS-------------------------------------------------VMVSYPTMSSYQVPMTQGSQG--------------------LPQQSYQQPIMLPN-QAGQGSLPATGMPVYCNVTPPTPQN-------------------NLR-----LIGPHCPSSTVPVMSASCR--------------------------------------------------------------------------------------------TNCASMSNAGWQVKF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MSX1-1", "uniprot_id": "ENC_DROME", "id": "Q8MSX1-1", "name": "Protein encore", "aln": "MSSTKSQVALATNIPTNLSSAASASTAAAAAAVVVVASANAAVASSANSSGVGSGSGPGPGSGAGVSGPVAAGTATAVATGSTVTAATSVAATTSTSVATISTSCSSSSINNINNNCGEECQSAAGSSNLGRQNSFGNRRGNMKGKHLTRSHAMRESTSPPRTPTPRAASEQQQQQLQGEQHEHNNNNNINSSSKAQSAGRGNSPLMETPAVIVTSQQPQQQQQQQQQQQQSVPPKPQQNVPLSNEAEFPKLSPPKKSGGQHNRTNSNGSGMEFNNNNNSSNKKFVVDMKANGLDNKPHNNSSTGVIFNSGMNYKAAERHDRHERHEMSSQNSNLSNNHDEEPYHYEPRGGGGGKKHRANTNAKGNKPRLKNLGGSSSGSIDLGGGGGNGNCNNMSNNGQSNNSSNNTSGFISRENSSEQYTDYGGTDLLVFFRDTLNKNPKDRNILLKIEKDLIDFVQENSRGCEYRFPPASSYNRMLIHRTAAFFGMEHNVDTETQQCVIVAVAKNTRIPEIR--FQSLVRDDARKS-----ILKRDTHSFDEVRQS-PYLCPLSLDRKAKSFEEREEDYDRARSRIFSRTGGNHDGYSGGGGDEECYGGWEQQQQQQKQSQPPRPKRPNGKMLQMQNSTESRDGMRSGGAVPKSHNFGNYGGPPSSGGPGNNSLPRGDSTNSIKSGRGGFVKQDSTGSTPWRLSPSSSGSIYHYDPSNLPPNQALQHSGNQYQSQNQGNSSSGGYNNYRKSSPHQQQQSQQQQQSQQHHQQQLQQPQQLHQQSSQQYATTELSCSSTESYAEEEAQSPGMECSEGYESYEQQSLPVQQQLSGNGDSASTKGDDCDSLASATACLSITTSTSTKNYDRIEVQKYKNQATSPNIPACCAVGEKLELEAGLPQEQEQEPMAGPSSSGSATSSVGITELPSSQTPLPMVNQVNCDLQSVSPSTTPYSQCEVKTPSQNHAPSAAVEEPKTTTWTYTQSYQAPDGSTVFHTTTTPNGAAPYCATTYQQGPDGSIYAVPQGMVYAAYPQPGVG-----------------TAGGASQPLFQLTTSSHPPAQTIFASPEAGAEIPGGTYMIPVFDPAQQPREGLIPAQAIYQTGPGGPGATTVMPMATAAAYPTAQFATAAPNGAPIYQAPLIYSSEPGGGAQLQQLPMAPYPIQYSYPYYHPISYYVPQQAVAAAPMVASQPQVGQAPMQQQAPHTGAGTTTGPPTVVSVSGQQHHQPHQQHHQQQQHSSNGSVVTSSAYGTRVKRTPGGGSIHYNPSYTPSSVAHAGGAHHPSAGSAQIIAAPAASTTTYHALPTLTLAHGGPATGTDLSGAGGAHVYALPAQHALIPTNIFPYAAAAAAAAGGPGGPPTTPQVVQQAPPPPPQSAPHHALITAAPFYPANGGNMDQGASQSAPSTPAAPGRQAPLFSTPPAPNNGSSGSSSAGGGGNSGGYHSNSSTPHYYQGQNSNEGYTSPYEKRNHGGGASGAHSVGVRKPYHPGGYNPRHSVPLGGIPSGAKTPLLNSNNEPTPRASPSSVSLGGASSSGGANSYPHRGPPPHTMGVKRDNKPNQLPLISGPPPSYAANSSPGVSSYESK-PPVRLNAGAASFRSQKSMNQDYRRSVSQRNSPSANGGGSGSHESSNNSPNSIVGSQSNSAANTPNAAAPPPPQPQPTLVSHSGGFVVLDQTTGAAMNASPPSLYGGGGGPNAGISGGAGASGAAGSNGGHQPGGGGGARSHIPTAQLHHSAAAAAAAAAGSQQATAAVLSGVAAAAALGGYNPNGASGVYFKYGQTYFAHPSVALPNSRRSPSNDIRPQMAQVAGMYPTMMIQARHPSRHPNPNYKGSRPR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05672-1", "uniprot_id": "RBS1_YEAST", "id": "Q05672-1", "name": "RNA-binding suppressor of PAS kinase protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTALDSRNWGLTPAMETGLFQKPQDRIFIIELENSIVSFINSNTESFQ--LRPMNSYYRLLSHQIAEYHNLNHVLARTQDSCVILFKGENFQKIEGKPLLQELQLNKKPEE------CASSSESIEKSNNN-------------------------RIFRILKRKE--------------------------------------------------------------------------------------------VGNECDYKIDGNTRTPNS-------------------------------------------------NLTANSNKDQKIEIDDKSSTDLEQERIEKERLYEQRKQEIFDKLNKSEDDVKSTNSSGSSDSDNEWS-------------------DWLNGD----------------------------------------------------------------------------------DSNTQTSNGS--------------------VSSSSPFNSSVTTIQVNKPQ----------------------------------------------------------------------------------------QQFYDSRRG---------RGGRRRGTNNYKDAYRGQSRRNKE-------------------------------NGGYQSGYSSPYLVYPPP-----------QMGGNSLPTYPLMYNPAGPAPGPAPSPMVMGNNTVFMNPYMYNMNPQGSCSFGTPIPMYPPYQYQYQYQYNTQYHSGPYSNTPSYNS------------------------------------------------------------NNYTRSSANKYHHFQGKNS---------------------------YSGAIPKRSDDSNSNKNEGIRRASVEGSPSSRD------------------------------TDSVEMKFDKLNI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .* : * ::.:** :::::*:.::.*: .. : : .** *:* *: * :..::* : ..**: .. : : : : . :. . . *::. . .. . : : :: .: : . : ..::. . : .** * . : :: : : : . : .. : : . * . . . . . * * .: . . .. .* . . ", "identical_positions": 24, "similar_positions": 97, "identity": "1.3%" }, { "cls_id": "homologset.agr.FB:FBgn0004876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924U5-1", "uniprot_id": "TESK2_RAT", "id": "Q924U5-1", "name": "Dual specificity testis-specific protein kinase 2", "aln": "----------------------------------MDRSKRNSIAGFPPRVERLEEFEGGG------------------GGDGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTR-EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD-SNLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK-RDENGYSAVVADFGLAEKIPDASIGSEK--LAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVG-DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQEEELERDRKLQ---------------------------------------------------------PTAKGLLEKVPGGKRLSSLDDKIPHKSPRPRRTIWLS---------------------------------RSQSDIFSRKPPRTVNVLDP----------------------------YYQPRDGATHTPKVNPFSARQDLKGGK------------------VKFFDLPSKSVISLVFDLDAPGPGTVSLADCQEP-----LAPSSRRWRSLPGSPEFLHQ-ACPFVGC---------------------------------------------------EESLSDGPPPRLSSLKYRVREIP-------------------------------------------------------PFRTSALSATSAHEAMDCSNPQEENGFVPRPKGTSPCSGAASEEMEVEE----------------------------------------------------------------------------------------------ERPRRAPVHFSISGISLQTQGEQ-------------------------------------------DG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCT9-1", "uniprot_id": "TESK2_MOUSE", "id": "Q8VCT9-1", "name": "Dual specificity testis-specific protein kinase 2", "aln": "----------------------------------MDRSKRNSIAGFPPRVERLEEFEGGG------------------GGDGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTR-EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD-SDLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK-RDENGYSAVVADFGLAEKIPDASIGREK--LAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVG-DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEELERDRKLQ---------------------------------------------------------PTAKGPLEKVPGGKRLSSLDDKIPHKSPRPRRTIWLS---------------------------------RSQSDIFSHKPPRTVSVLDP----------------------------YYQPRDGATHTPKVNPFSARQDLKGGK------------------VKFFDLPSKSVISLVFDLDAPGPGSTTLADCQEP-----LAMSSRRWRSLPGSPEFLHQ-ACPFMGC---------------------------------------------------EESLSDGPPPRLSSLKYGVREIP-------------------------------------------------------PFRTSALSAASGHEAMDCSNPQEENGFGPRLKGTSLCTGAASEEMEVEE----------------------------------------------------------------------------------------------ERPRRASVYFSISGISLQTQAKQ-------------------------------------------DG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S53-1", "uniprot_id": "TESK2_HUMAN", "id": "Q96S53-1", "name": "Dual specificity testis-specific protein kinase 2", "aln": "----------------------------------MDRSKRNSIAGFPPRVERLEEFEGGG------------------GGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFTC-EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD-SNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK-RDENGYSAVVADFGLAEKIPDVSMGSEK--LAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVG-DCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQEEEQERDRKLQ---------------------------------------------------------PTARGLLEKAPGVKRLSSLDDKIPHKSPCPRRTIWLS---------------------------------RSQSDIFSRKPPRTVSVLDP----------------------------YYRPRDGAARTPKVNPFSARQDLMGGK------------------IKFFDLPSKSVISLVFDLDAPGPGTMPLADWQEP-----LAPPIRRWRSLPGSPEFLHQEACPFVGR---------------------------------------------------EESLSDGPPPRLSSLKYRVKEIP-------------------------------------------------------PFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASEEMEVEE----------------------------------------------------------------------------------------------RPAGSTPATFSTSGIGLQTQGKQ-------------------------------------------DG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63572-1", "uniprot_id": "TESK1_RAT", "id": "Q63572-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "-----------------------------------MAGERPPLRGPGPG---ETPVEGP---------------------GGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVR-REDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLAKMPLA---------------------------------------------------------KAPLTYNQGSVPRGGPS---------ATLPRSDPRLS---------------------------------RSRSDLFLPPSP-------------------------------------ESPPSWGDNLTRVNPFSLREDLRGGK------------------IKLLDTPCKPATPLPLVPPSP-LTSTQLPLVASPESLVQPETPVRRCRSLPSSPELPRRMETALPGP------------------------------------------GPSPVGPSTEERMDCEGSSPEPEPPGPAPQLP----------------------LAVATDN-----FISTCS-------------SASQPWSARPGPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTE-------------------------------------------------------------------------------PSPPPSAPREQEEGLPCPGCCLSPFSFGFLSMCPRPTP-----------------------------------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70146-1", "uniprot_id": "TESK1_MOUSE", "id": "O70146-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "-----------------------------------MAGERPPLRGPGPG---EAPGEGP---------------------GGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVR-REDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQQPEATPLAKPPLT---------------------------------------------------------KAPLTYNQGSVPRGGPS---------ATLPRPDPRLS---------------------------------RSRSDLFLPPSP-------------------------------------ESPPSWGDNLTRVNPFSLREDLRGGK------------------IKLLDTPCKPATPLPLVPPSP-LTSTQLPLVTTPDILVQPETPVRRCRSLPSSPELPRRMETALPGP------------------------------------------GPSPMGP-TEERMDCEGSSPEPEPPGLAPQLP----------------------LAVATDN-----FISTCS-------------SASQPWSPRSGPPLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTE-------------------------------------------------------------------------------PSPPPSAPREPEEGLPCPGCCLGPFSFGFLSMCPRPTP-----------------------------------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15569-1", "uniprot_id": "TESK1_HUMAN", "id": "Q15569-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "-----------------------------------MAGERPPLRGPGPGPG-EVPGEGPP------------------GPGGTGGGPGRGRPSSYRALRSAVSSLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVR-REDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEP-----APLT---------------------------------------------------------RTALTHNQGSVARGGPS---------ATLPRPDPRLS---------------------------------RSRSDLFLPPSP-------------------------------------ESPPNWGDNLTRVNPFSLREDLRGGK------------------IKLLDTPSKP--VLPLVPPSP-FPSTQLPLVTTPETLVQPGTPARRCRSLPSSPELPRRMETALPGP------------------------------------------GPPAVGPSAEEKMECEGSSPEPEPPGPAPQLP----------------------LAVATDN-----FISTCS-------------SASQPWSPRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHSLPRAAALERTE-------------------------------------------------------------------------------PSPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPTP-----------------------------------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEW6-1", "uniprot_id": "E7FEW6_DANRE", "id": "E7FEW6-1", "name": "dual-specificity kinase", "aln": "------------------------------------MSIFMDQDDLDPEAS-DSLMHGV-------------------------HGAHRPRPSSYRALRSAVSSLARLDDFIC-EKIGSGFFSEVFKVQHRSTGQVMALKMNTMASNKANMLKEVQLMNRLRHPNILRFVGVCVHEGHLHALTEYINGGNLEQLLN-SDVLLSWSVRINLSLDIARGLQYLHSKGIFHRDLTSKNCLVR-WENGHCTAVVGDFGLAEKIPDHSEEAEKQSLAVVGSPYWMAPEVLRGERYNEKVDVFAYGIILCEIIGRIQADPDFLPRTEDFGLDVEAFRLMVE-DCPAHFFNLAVVCCGMSPDSRPCFSEVVAELEKRESDELQT----DHLES---------------------------------------------------------DVQDQMSTSSTPLSRAH---------SLDIASDPVLC---------------------------------RSKSAVLLPP----------------------------------------SPILNNTTPMRVNPFSQRQDLNGGR------------------IKLFDTPSKSVISLTFTLPPPPDPSSPVPPR-----------SHRRTQSLPCKPQD-IQSLYSTAEKRM----------------------------------------NHQSIMDRDVNMLEIGGDSVLTMSSGSIADLSGVLDPNTTGSNPEQEENLELRSQDVLADDSGLPLDLEVLSPNK--------WRSTEELMDCTSSPDTLDGAVDSTKQFSNGWS-SPVSNGPPSLPPLLDLDNNNSTIPINRPLGWG-VNN------------------------------------------------------------SNG-ATTPLTPTEQDEVVSCPGCCLAGMSF--PSICTRRAR------------------------------------QNPYKNLNG----DAAGKRLLCK---ALPPSPT--EPNITLPGTRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q613-1", "uniprot_id": "A0A8M9Q613_DANRE", "id": "A0A8M9Q613-1", "name": "dual-specificity kinase", "aln": "----------------------------------------MDQDE-NQEPC-EPPLHAL-------------------------YGPNRIRPSSYRALRSAVSSLARIDDFFC-EKIGSGFFSEVFKVQHRITGQVMALKMNTLASNKANMLREVQLMNRLCHPNILRFLGVCVHEGQLHALTEYINGGNLEQLLD-SDIYLSWTVRIGLSLDIARGLQYLHSKGIFHRDLTSKNCLVR-CENGAFTAVVGDFGLAEKIPDYSDGVEKQPLAVVGSPYWMAPEMLRGELYNEKVDVFAYGIILCEIIARIEADPDILPRTEDFGLDVDTFEHMVG-DCPPSFLQMAVDCCNMNADSRPAFSEIVVMLERIERERVKS----EIPV-----------------------------------------------------------ILEPIAIDVSPYRRRS---------SPCHPCDQRLS---------------------------------RSQSDMLPPAT---------------------------------------SPCLG--TPARVNPFSLRQDLNGGR------------------IKLFDTPSKSVISLTFTLPPPPDPSASPPLSGSPG----LRGPPRRCRSLPCTPELGRQLPFRDQEVEE----------------------------------------DRSEELGQETKDKELEGQQDAVEDSGLVLDLDMVSLERVE----EEEE-----DEEVEKEGQSLTEPMDCSS-------------SPDTTEGNVSGKRLISGSSYSSSLQSNGWA-TPISNGPPLLPPLPRLDNNNGVLRPGRPFAWVRLNG------------------------------------------------------------YRGPAPEPLPPTEQDDVISCPACCLAGFSF--PSLCLRGAPPSRRG-----------------------------PPRRPYRTFNGGDASTATAKGLLCRGATGLAPSTASCEPGLPLPEAQT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NDD2-1", "uniprot_id": "A0A8M1NDD2_DANRE", "id": "A0A8M1NDD2-1", "name": "", "aln": "MHMN---------------------------------SLLNQCTEISRMCEVDVSSE------------------PTSPTLCNESSDTYCHVDRWQKLRTAVRKLEFWENFTH-ELIGSGFFSKVYKVIHNTTRKVMVVKIYKNDVDQDSIVREISLLQKLSHPNIVRYLGICVKEDKLYPILEYVSGGCLEELLARQDVPLCWREKVDLASDITRGMIYLHYKNIYHRDLNSKNCLIRMTARGR-EALVTDFGLAREVVELPSKDRK--LSLVGSAFWMAPEMLRGEPYDRKVDVFSFGIVLCEILARIPADPEILPRTQDYGLDVSAFRKMVSG-CPQRLLELAASCCLLDAFRRPSFTELQDELGEIAESLETPHSELTTG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE06-1", "uniprot_id": "Q9VE06_DROME", "id": "Q9VE06-1", "name": "dual-specificity kinase", "aln": "MSLNQHSGPGPPSEICGLSVDQVDSSAASPFIWPSTAGMCTTATTVTTSTNGDATAEAPVKHQPLHNGGWIGNGLPPAPVTRTISSDRLVTGSSCRALRTAVSALYSVDDFVK-EKIGSGFFSEVYKVTHRTTGQVMVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRNLANDQYEAVVGDFGLAAKIPVKSRKSR---LETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPMDTPPVFLRLAFYCCLYDAKSRPTFHDATKKLTLLLEKYEHESSAGASPLSSLELINCSPGGSDSENVTLTPRASVPTVATICTAPAGTLTPRHLQEVDEDGFRFPSKKSASAALPGTPNGSAGSSGFDDHILKSRVRRATQKLEAEILLHRRSLSENIIHFPMHTSPSDKARCHQMQRQRSSTHSPTPPRQLSSVQLPATSIPDPPPLPKPVPAVLTLRKVGDPQYKPTSEKDHNGSKPNPFEALAQLRGVKKILDANPKTYAAGVGDLFSSCFEMLAPFFKELAAMQSKAGAQGGGTSTEETSTGNKASAATPSEPKSLPVSPHMTRKYSAIELRLPQRISNAAPPAVTSAPPPSIALPTDEDDCDDCNSEGEDPDGGGNCADAESSSDDSAVRPSTVPTARKYRANSLYAHPLFRGSNGTSMKSTSTGEFESPTLLKASASTITLTASVGATNSCEDLTESARKSKEQASSGATAAVQALPTPMSGCSTRLVETPVSVSSCTDLELDELKNTCDLNELKNSCEQLPLKTNLTRRDSIESGFFSCFNEESDAAITNNSFGRQLNGIGSLGFGCGGGGNSSNCCYEKLKTQLMLDACVSADSEINDKLASLCRCCYYATSTSNAAVTAAAAAAQQQQQSHLLNDTSSTSSSVLLIDNDPAVIGGNTSSSTALDSMDDLDADIVASRRTHQRRYTCHHALLSGNGSESQMAATASLINRLALDSEIHTLLQRSPFATNQLLYCKNRTSSIYTDSSDDISSLAGSDSLLWDDRSFTALPSTRSAQIAKIVEYFERKRQDSSPPSVHHRNGNGTVAAAVAASALGSNYLSYESRRYSDFKRHLNADGLCFDLDKKPAQQRMMVCEGAVKSKLPIFDKKKQQQGG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : :*. * ::* * **:****:*:** *. : :**.:*: :: . ::*:.*:::* *.**: ::*:**::.:*:.: **:..* **:** . * :: *: .*: *: *:* .::****.*** *:: *:* ***** :: . * ***.:*::** *:.: *:.. ***::**: **::.*: ***: :*** .:*** :* : * :: :: ** .. *. * : * ", "identical_positions": 88, "similar_positions": 92, "identity": "7.23%" }, { "cls_id": "homologset.agr.FB:FBgn0004878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZS43-1", "uniprot_id": "A0A8I5ZS43_RAT", "id": "A0A8I5ZS43-1", "name": "", "aln": "-------------MDLGT-------------------AESTRCTDPPAGKPPMAAKRKGGLKLNAICAKLSRQVVVEKGAEAG-------SQAEGSPLRPRDRERSG---PESAATRAPRSEEDKRRAVIEKWVNGEYCEEP-APTPVLGRIVREG--SELPPEGVYMVQPQGCSDEEDHAEEPSKDNSILG---EKDSDG--TKDDSGPSAKQAS---------GEASSLRDYAASTMTEFLGMFGYDDQNTRDELARKISFEKLHAGSTPEVVASSMLPSSEDTLSKRARFSKYEEYIRKLKAGEQLPWPAHG------SKAEDRAGKEVVGPLPSLRLPSN----TAHLETKATILPLPSHSSVQMQNLVARASKYDFFIHKLKTGESLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGTTKIPP--------APSLVPTPLTNVPSAPS----APGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQ-YREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCS-VYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPASLLGTKDTEHEESSNDDLVDFSALSSKNSSLSASPNSQQSSAS-----LAAAAAATTAEAVPSAAKPPNSKMAGLLPQGLSGSIPLALALSNSGLP-TTTPYFPLLPGRGSASLPVGSPGLLGSMTSGATTSATPDMP-ALMASGAGDSAPTAATSLSVPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQSTPTKFPQAQVKQEP-DSAGTPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPSLGNLLNIKTEVEGSPAGEPS---PFLGKAVKALVQEKLSEPWKVYLRRFGTKDFCDAQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGTAKGTTEASFPTSAAETKPPLAPSSPPAPPGTMVPGSSLEGPAPSPVS-VPSTPTLLAWKQLASTIPQMPQIPSSVPHLPTSPLATTSLESAKPQVKPGFLQFQDNDPCLATDCKYASKFHFHCLFGNCKYVCKTSGKAESHCLDHINPSNSLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVP-------------------PSQGPP----------SLMDAETDEGMDYTG-CSPGAASSESSTMDRSCSSTPVGNESTAAGC-------------PVPPPPPLPPPAAAGDEAARGAAPPTLTPSFPPAVLRPPLPPLPCLFSPSCLSYSLLSTTLGASRGLAHPISSPSSFPPITATPTPVKRDAPLVQDAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDTACQFSLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTYPGCRHTVVGMSQMDSHKRKHEKQERGEPPAAS------------------------------------------------------------PGAPVSLDGSLTLAAEQGSLLFLQTAAAGLGL-LGDTGDPGPP-VTAPGTRDAPAAPAPVAAAAATTTTTTTTTTTSSAAGESSQEDDEEELEMPEEEAEEDDEDDDEEDDDDEDDDDDDDDEDLRTDS-EESLPEAAGEAG---ARTP----LAALGGPGPAPTAASP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWL2-1", "uniprot_id": "CASZ1_MOUSE", "id": "Q9CWL2-1", "name": "Zinc finger protein castor homolog 1", "aln": "-------------MDLGT-------------------AESTRCTDPPAGKPPMAAKRKGGLKLNAICAKLSRQVVVEKGAEAG-------SQAEGSPLHPRDKERSG---PESGVSRAPRSEEDKRRAVIEKWVNGEYCEDP-APTPVLGRIARD---QELPPEGVYMVQPQGCSDEEDHAEEPSKDNSVLE---EKESDGTASKDDSGPSTRQAS---------GETSSLRDYAASTMTEFLGMFGYDDQNTRDELAKKISFEKPHAGSTPEVAASSMLPSSEDTLSKRARFSKYEEYIRKLKAGEQLPWPAHG------SKAEDRAGKEVVGPLPSLRLPSN----TAHLETKATILPLPSHSSVQMQNLVARASKYDFFIHKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGPTKIPP--------APSLVPTPLTNVPSAPS----TPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQ-YREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCS-VYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCMYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPASLLGAKDTEHEESSNDDLVDFSALSSKNSSLSASPTSQQSSAS-----LAAAAAATTAEAIPSATKPPNSKMAGLLPQGLSGSIPLALALSNSGLP-TTTPYFPLLPNRGSASLPVGSPGLLGSMSSGATTSATPDMP-ALMASRAGDSAPTAATSLSVPPASIIERISASKGLISPMMARLAAAALKPSATFDPGSGQQPTPTKFPQAQVKQEP-DSAGTPGPHEASQDRSLDLTVKDPSNESNGHAVSANSSLLSSLMNKMSQGNPSLESFLSIKTEAEGSPAGEPS---PFLGKAVKALVQEKLSEPWKVYLRRFGTKDFCDAQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGTAKGTPEASFPTSAAETKPPLAPSSLPAPPGTMVAGSSLEGPAPSPVS-VPSTPTLLAWKQLASTIPQMPQIPSSVPHLPTSPLATTSLESAKPQVKPGFLQFQDNDPCLATDCKYASKFHFHCLFGNCKYVCKTSGKAESHCLDHINPSNSLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVP-------------------PSQGPP----------SLMDAETDEGMDYTG-CSPGAASSESSTMDRSCSSTPVGNESTAAG-----------------------------------------------------------------------------------------------------------------NTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDTACQFSLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTYPGCRHTVVGMSQMDSHKRKHEKQERGEPPAAS------------------------------------------------------------PGAPVNLDGSLTLAAEQGSLLFLQTAAAGLGL-LGDTGDPGPP-VTASGTRDGPAAPTPAAAATTTTTTTATATAT---AGESSQEDDEE-LELPEEEAEDDDEDDDEEDDDDEDDDDDDDDEDLRTDS-EESLPEAAGEAG---ARTP----LAALGGPGPAPTAAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86V15-1", "uniprot_id": "CASZ1_HUMAN", "id": "Q86V15-1", "name": "Zinc finger protein castor homolog 1", "aln": "-------------MDLGT-------------------AEGTRCTDPPAGKPAMAPKRKGGLKLNAICAKLSRQVVVEKRADAG-------SHTEGSPSQPRDQERSG---PESGAARAPRSEEDKRRAVIEKWVNGEYSEEP-APTPVLGRIAREG--LELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALE---EKDSDGAASKEDSGPSTRQAS---------GEASSLRDYAASTMTEFLGMFGYDDQNTRDELARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPS------TKTEERVGKEVVGTLPGLRLPSS----TAHLETKATILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGPAKVPP--------TPSLAPAPLASVPSAPS----APGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQ-YREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCS-VYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLSASPTSQQSSAS-----LAAATAAT--EAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLP-TPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSAASATPDTP-TLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPS---PFLGKAVKALVQEKLAEPWKVYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSSLEGPAPSPAS-VPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVP-------------------PSQGPP----------GLMDAETDECMDYTG-CSPGAMSSESSTMDRSCSSTPVGNESTAAG-----------------------------------------------------------------------------------------------------------------NTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQFSLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPA----------------------------------------------------------PGPPISLDGSLSLGAEPGSLLFLQSAAAGLGLALGDAGDPGPPDAAAPGPREGAAAAAAAA-------------------GESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDS-EESLPEAAAEAAGAGARTPALAALAALGAPGPAPTAASSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6A1-1", "uniprot_id": "A0A8M3B6A1_DANRE", "id": "A0A8M3B6A1-1", "name": "", "aln": "MKVTCLTGFNFDYPEYGTGRERAEAREKIEEEKTTCFAERSLCTEKTSGKSTMAAKRKGGLKLNAICAKLSRQVVYDGSSQNAEGDSDLVDNSERGSLHYDEGDRPESDFPEGLTLTQSLEEDQKRREAIEKWVNGEYGEDPQCLEGVEHRVLKPNNGEDGPPEGVYMVQPKGCSDEEDNAEEADTMPGSHEGSYHEDSEGSPRKDDSFQPTTEAPPRPAPFTPPGDSSALRDYAANTMNEFLNMFGYDDQQVRDELAKKISFEKLKAATS----DPSSLSSEE--ATRRARFSKYEEYIRKLKAGETLPWPVHTKPEVLNSKMTLTPEKSAALIQPTLTAGSEGQIFPPGMDHKQSSLNPAPTNQSHIQNLASRASKYDYFIQKLKMGESLREQNGNSYKRPSKYDLENVKFLHLFKPGEGNPDMGGAIAFKTGKVGRPSKYDIRNIQKLIPGKVDPPVLSSVLPATAGTPGPPVINTAAPAGVVGPPGLPMDQEGHLGFNT-DFMKSSFSKTDSITTGTVSSVKNGLPPEKPAT-EDVNVYQKYIARFSGSQHCGHVHCAYQ-YREHYHCMDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCS-VYYHGCHLNGKSTHYHCMQVACNKVYTSTSDVMTHENFHKKNAQLINDGFQRFRAVEDCGTVGCQFYAQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRQGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLTSSFLLPKE-EQDESSNDDLMDYSAISSKNSSLSASPTTQQSSTIPHLLPTPTTTMCSSQSVKPTAALPPASRISTLLSQALPSNVPMALALSNSALAGASNAFFPLIP-RMPMPLPPSAAGLISAATSVAHSMPSDSLPQTSTPTGDLAAATVASTPTSFAASSIMEKMSASKGLISPMMARLAAAALKPSGNPDAGMGQAG---QFNPVEVKQEPVDGAAS---QESIQEHSLDLSKKDHSAESNGHPAPGNTSLLSSLMNKMN---PGFFNALDLKSELEGAQAADGSDAAQYLSRVMKRSSPEKPTELWKTYLRRYDIDDFCEAHCDFLHKIHFHCLVEDCGALFSTVDGAIKHANFHFRAN---LKVKSEPPFNESKESNDS--GPNQMSAP-ISMAKTPPVEVPSLAVSGGYSSSPSFQAWKQLAGSIPQLPASMPSMP--ATSPLATTSLENAKPQVKPGFLQFQDNDPCLATDCKYSNKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFSYYSLQCLCPNQHCEFRMRGHYHCLRPGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECGRHGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPSQVVSHAHQPEEMQRMASLASSGMVGSHHNMNPNFSNMMEDNDDYMDYTAGGSPLGLSSESSNQDRSCTSTPVGNDSSPAGPGCQVPAPATTTSADSPPSQSAPPPPPPSLPPPHQPALQSQPPSLSSALLRPPLPSLPYLLSPSCLSYSLLSASLGATRSVVMPTN-TTAFSPIIPTSSSVKNDVPIVQDAAGNTISIPTATGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRYDLYEDCKDTACQFSLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKSSLCCNFPDCQFSGNSTHFHCLRCGFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSVDCEVADCKYKLKCSHFHCTYPECKHTVVGMSQMDSHKRKHEKQERGELPSVSPNQDGNHHHHHHHHHHHAGLAIPSMPMNLPPTSPSTPGLTHNNMTMFHLPSTGAVNEYEHPGSAVNLDSSLNLGTDTNSSLFFLKNAAGLGL--SDSMDLSKKMHRDPLSLAPGSGPIASMG------------------LGNPQDDTTGTSGDLEDDLSPEEEPIAEDDDDDDDEEEDEAEDDMNTDSYEDSMPEPEVDKDNGESFDASMNHAETSQLDKEDPEAEP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7M3M8-1", "uniprot_id": "CAS_DROME", "id": "Q7M3M8-1", "name": "Transcription factor castor", "aln": "--------------------------------------MSNQMEFIMQLYMMNLMKQQQQMQLQLPQQQQQQQLAGYTYTQNE-------DISSSTSVQQQQQQQQE---------QLQQPQPDLRKTRTHKRISSQNTNCS---------------------------SSRSCSPNSNLIAFQPQ-----------QYPGATAATPSTPNSHPSN-------------LVNQMLLQSLPPLTQLMLQQQQQQHLLTTSNLLLTPTHTPSS---------LGKQDPLQHPLLLGQFAGSEQMATNNFLQSSTVTS---------TPIEREKAATPAPSAGATAG---------------NLSAAQVKFEQESADDDEDDDKPLSSLTS----CSSSGHTNASSEKLLLSGVHPLESTTDSLDSPSMYTPVKQPADSS--------YGLITPVDSDLTP--------NTPLQPTQTISLLTPPS--------SEQSKSLVSLSAASGLDALLQNEEVLKN---------------------------LRKVSSYLECENSLCRQENLREHFHCHEEPCQGKILSKKDDIIRHLKWHKKRKESLKLGFARFSSSDDCAPAYGEGCAYNWKQTHYHCVYEHCPKVYVSTSDVQMHANFHRKDSEIVNEGFRRFRAHETCRIEDCPFFGKKISHYHCCREGCTHTFKNKADMDKHKTYHLKDHQLKMDGFKKILKTEVCPFDACKFSTVCNHIHCVREGCDYILHSSSQMISHKRKHDR-------QDGEQAYQQFKIKQDVEESSLDAMPQQQQQQQQQQPTSLSQSQSSSSVCG----------------GSNTSTPLSSLSAEHFLARKRGRPPKKIQLPADAQQ------------------------------SEAKRLKVEDES----------SNPAMLLPQSQPAAAVHP---LTSGLFPGLLPAAAAPGVDPTAP---------------------------------------------NFQLTHLMALFQLQNPLFYQNLYPGMTQNSSMLGNLAALSAASAAAAAAAAAN-----------------------------GAGVQQPKAEFSFKPEFKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:: ::*: : .:*:. :: . :. . : : :: : : *: .* :..: : . ..:.** :.: : * * : : :.: .:: : :: ::*: : : :: : :: :: .: : :.:: : . . . .. :... * : .. . *: . .. * : .*. ..* : ..* *..*: *. . . ..*.* .: :.. .: . .: * .. * :.*: : . :.:.: . :.: :.: : :.. : :.*. .* : * : ***:** : *: : ::.*:*:*** : ****.:**: ** ***. ***: .* .** * *.*****: * ***.***** * ***:*:::::*:**:**** * * .* *:.:* :*:** * ***.*****.*::***:**:**. *****: * * * ::.* :*.. **:**:* **.: : *:*** ******:* * . . : :*** * : : . ..::.. * * . ..**. ..:: * * : : . * : *. .. * : . . : .. . . ..::: :.**:. ::. **..:.*:. : . . *. : ..* *. . : . :.: .: *. : .. : :.:* .* .*: ", "identical_positions": 162, "similar_positions": 280, "identity": "7.81%" }, { "cls_id": "homologset.agr.FB:FBgn0004880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQ03-1", "uniprot_id": "SCRT2_HUMAN", "id": "Q9NQ03-1", "name": "Transcriptional repressor scratch 2", "aln": "MPRSFLVKKIKGD------------------------------------------------------------GFQCSGVPAPTYHPLETAYVLPGARGPPGDNGYAPHRLPP-SSYDADQKPG---------------------LELAP-AEPAYPPAAPEEY-----------------------------SDPESPQSSLS---ARYFRGEAAVTDS----------------------------YSMD-------------------AFFISDGRS------------------------------------------------------------------RRRRGGGGGDAGGS--------GDAGGAGG---------RAGRA------------------------GAQAGG-------------------------------------------GHRHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHLLTHNLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAACAKAAE------------PPPPTPAGPAS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BTH6-1", "uniprot_id": "SCRT2_MOUSE", "id": "Q8BTH6-1", "name": "Transcriptional repressor scratch 2", "aln": "MPRSFLVKKIKAD------------------------------------------------------------GFQCSGVSAPTYHPLETAYVLPGTRGPPGDNGYVAHCLPP-SGYDGEQKPG---------------------LELAP-AEPAYPAAASEEY-----------------------------SDPESPQSSLS---ARYFRGEAAVTDS----------------------------YSMD-------------------AFFISDGRS------------------------------------------------------------------RRRRAGAGGDAAGA--------GDAGGGGGGGG---GGERAGRS------------------------GATAGG-------------------------------------------GHRHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHVLTHNLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKHCEAACVKAAE------------PPP--SAGPAS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A919-1", "uniprot_id": "D4A919_RAT", "id": "D4A919-1", "name": "Transcriptional repressor scratch 1", "aln": "MPRSFLVKKVKLD------------------------------------------------------------TFSSADLDS-SYGRARSDLGVR-----LQDKGYLSDYVGPASVYDGDAEAA---------------------LLKGPSPEPMYAAAVRGELGPA----------------------ASGSAPPPTPRPELATAAGGYINGDAAVSEG----------------------------YAAD-------------------AFFITDGRS------------------------------------------------------------------RRKAANANAASAPSTASVAAPDSDAGGGGGPGTRGSGSGSASRG------------------------GTRVGAG------------------------------TEARAGPGATGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGA------------SGPATPAPPQLSPVQA-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M85-1", "uniprot_id": "SCRT1_MOUSE", "id": "Q99M85-1", "name": "Transcriptional repressor scratch 1", "aln": "MPRSFLVKKVKLD------------------------------------------------------------TFSSADLDS-SYGRARSDLGVR-----LQDKGYLSDYVGPASVYDGDAEAA---------------------LLKGPSPEPMYAAAVRGELGPA----------------------ASGSAPPPTPRPELATAAGGYINGDAAVSEG----------------------------YAAD-------------------AFFITDGRS------------------------------------------------------------------RRKAANANAAAAPSTASVAAPDSDAGGGGGPGTRGSGSGSASRG------------------------GTRVGAG------------------------------TEARAGSGATGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGA------------SGPATPAPPQLSPVQA-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWW7-1", "uniprot_id": "SCRT1_HUMAN", "id": "Q9BWW7-1", "name": "Transcriptional repressor scratch 1", "aln": "MPRSFLVKKVKLD------------------------------------------------------------AFSSADLES-AYGRARSDLGAP-----LHDKGYLSDYVGPSSVYDGDAEAA---------------------LLKGPSPEPMYAAAVRGELGPA----------------------AAGSAPPPTPRPELATAAGGYINGDAAVSEG----------------------------YAAD-------------------AFFITDGRS------------------------------------------------------------------RRKASNAGAAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRG------------------------GTRAGAG------------------------------TEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGA------------GGPAAPAPPQLSPVQA-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZK2-1", "uniprot_id": "Q9VZK2_DROME", "id": "Q9VZK2-1", "name": "Transcriptional repressor scratch 1", "aln": "MPRCLIAKKWKAYPWLDRTEDTSNQQQQQEQSAPNSPRELEELHLKSRRSTLDDDEEIDVVGDKFLIKLEKQRTTADAAAAAATSSEAATSHSSNSSNMEASATTTTSKCWGPSSPTAGTTAPSPPPHSPEAATRVAGNVYNGYTRELSPLHYTAYLPRMESEITVIRAAATALVAARTSGNGSGDQHLAAYQTPPSSTTSSPSCSPSGAGDRYSPLSSGQTSSERKCFSSTGATLSLPPKKKDIYRPYSLDDKPAHGYRRRVPAEEDLHAAHAILDLSASTAFHPPTQPHQLQQQQQQQQQQHQHHHSQQQHLAPQQHHYLPLQQQQQQQAHHTHLPTLEAHAHLRSTSSIAELAAAASVVNEQRPASNASSASSNHMPSSPSSNSSSSSSQVQNENSNTTNTNPDGDGCLQDGEHSGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAASGVPTPDQQKTKYTCSECGKQYATSSNLSRHKQTHRSLDSQSAKKCHTCGKAYVSMPALAMHLLTHKLSHSCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSVDKNFECKRCHKTFALKSYLNKHLESACLKDEEELMMSMSLSMHDSNSESGASMASSPPHEFLERVKLEGSGGATYAM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.::.** * : : : : . .. * * . .. .* . * . * : * :. .. : . :.::.. *: * *. * * : * . . :. : .:*..... .. . * *. :::*.**** ******************** *::* ****.******:***:***.* *.****** **********:********:***********************. *::.*::*.*:*******:** *:** * . * ", "identical_positions": 131, "similar_positions": 73, "identity": "20.06%" }, { "cls_id": "homologset.agr.FB:FBgn0004882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C279-1", "uniprot_id": "CPEB1_RAT", "id": "P0C279-1", "name": "Cytoplasmic polyadenylation element-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFSLEEESGRIKDCWDNQEVPALSTCSNANIFRRINAILDDSLDFSKVCTTPINRGIHDQLPDFQDSEE-------AITSRMLFPTSAQESPR-------GLPDANGLCLGLQSLSLTGWDR-PWSTQDSDSSAQSNTQSVLSMLQNPLGNVLGKTPLSFLSLDPLGSDL-DKFPAPSVRGSRLDTRPILDSRS------SSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSMTGNGPRDPLKMGVGSRMDQEQAALAAVAPSPTS--APKRWPGTSVWPS-----WDLLGAPKDPFS-----------------IEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFELEKSVRALLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVWSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVTAAFVEIKTTKFTKKVQIDPYLEDSLCLICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKN-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70166-1", "uniprot_id": "CPEB1_MOUSE", "id": "P70166-1", "name": "Cytoplasmic polyadenylation element-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFSLEEAAGRIKDCWDNQEVPALSTCSNANIFRRINAILDDSLDFSKVCTTPINRGIHDQLPDFQDSEE-------TVTSRMLFPTSAQESPR-------GLPDANGLCLGLQSLSLTGWDR-PWSTQDSDSSAQSSTQSVLSMLQNPLGNVLGKAPLSFLSLDPLGSDL-DKFPAPSVRGSRLDTRPILDSRS------SSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSMTGNGPRDPLKMGVGSRMDQEQAALAAVAPSPTS--APKRWPGASVWPS-----WDLLGAPKDPFS-----------------IEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFELEKSVRALLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVWSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVTAAFVEIKTTKFTKKVQIDPYLEDSLCLICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKN-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZB8-1", "uniprot_id": "CPEB1_HUMAN", "id": "Q9BZB8-1", "name": "Cytoplasmic polyadenylation element-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALSLEEEAGRIKDCWDNQEAPALSTCSNANIFRRINAILDNSLDFSRVCTTPINRGIHDHLPDFQDSEE-------TVTSRMLFPTSAQESSR-------GLPDANDLCLGLQSLSLTGWDR-PWSTQDSDSSAQSSTHSVLSMLHNPLGNVLGKPPLSFLPLDPLGSDLVDKFPAPSVRGSRLDTRPILDSRS------SSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSLSGGGPRDPLKMGVGSRMDQEQAALAAVTPSPTS--ASKRWPGASVWPS-----WDLLEAPKDPFS-----------------IEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSAAFVEIKTTKFTKKVQIDPYLEDSLCHICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKNRDSS-------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGX5-1", "uniprot_id": "CPEB1_DANRE", "id": "Q9YGX5-1", "name": "Cytoplasmic polyadenylation element-binding protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFSLRENP-RLLNCLDS-DIPALSTCSNADAFCRMNTMLGNSLDLSGVCTTPTAKCKRDPFNDRPDSDLS------AVRSRMLFPSGGQDSSR-------GLPDVNNWGLGLQSLSLSDWER-PWSSHDTDPSVKTNTASLQGILGTPSQLTNKLSNYSDSSIG--ATDFLEKFPG----MARLNSQSFLDSHS------ISPVDSETSGFSSGSDHLSDLLSSLRISPSVPFLMSSMQ--RDPLKLALDSRMDHSSSPLTPPPSASPSGSLSHRWPGASIWPS-----WDLMKTPESPFS-----------------IEREAWLHRQAASINEATFTWSGQLPPRHYQNPVYSCKVFLGGVPWDITEAGLINTFKCYGPLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFESDKSVRALLQDCTEDLLHPEGYSEYYFKMSSRRMRCKDAQVIPWVISDSNYVSCPSQRLDPRNTVFVGALHGMLNAEALASIMNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSAAFVEIKTPKFTKKVQIDPYLEDAICQSCSREPGPFFCRDKTCFKYYCRSCWHRQHSMDILSNHRPLMRNQKKRDAN-------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCN7-1", "uniprot_id": "Q9VCN7_DROME", "id": "Q9VCN7-1", "name": "", "aln": "MPLLQQYDTPDCSGSGGNMRALSGGSTTELLQKHSISSYLDHHHQQQQQQQHHLQLQQHQQQHSLLERCNDDGLISFINDPITLNDLLGLCGASTANEVVGTGQTPSTSAPILGAGGGGRANGVTAGAATATGVGVGAGGTLPGPGVPSIQGGGGGGVVGQQTNASCNTSAANPSASFGGNGSSSDVNNLLLASAAAAAAAAAGDGAQLSANAAAYAPLTPSSTHSSASPGTKSNFDYFQFENVAQSNPLKAFQRTNISFDCSAPLSPSTPTSIYNRSFHSSPLVSDSSNSSSGIGLSMDSINMFYNQQQQQQQPEQQGYTSLGNSMGSGLGLSLANASTRSNSPESQNSSNSTTEQNLLDMINLLSVNSNKIPHQQQQQQQQQQQQQQQQQQNQQQLQVQQQHQLQQQFVNLNRNYEQQISANLGSQQHGFEHNGVGVGASSSGNENCFSQYNLENITSVDMELAKLQNLQRINTLKLLHAQAQQMPLINQLLQSYAGNAIGSVGGSNLGNLMSAGGSSLMTEMAGNVGGIITTNDGHLDRVAKFYKSSAALCDATCTWSGHLPPRSHRMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKE-------QQAAQPKGYVYIIFESDKQVKALLSACVLQVDDSHCGRNYFFKISSRRIKSKDVEVIPWIIADSNFVRSSSQKLDPTKTVFVGALHGKLTAEGLGNIMDDLFDGVLYAGIDTDKYKYPIGSGRVTFSNFRSYMKAVSAAFIEIRTTKFTKKVQVDPYLEDALCSICGVQHGPYYCRELSCFRYFCRSCWQWQHSCDIVKNHKPLTRNSKSQSLVGIGPSSSNVSLPFSGQRSIRDNRMGNGQHQQHQQHQYQQQKHRQLQEYSQPHSLNVMGNSGAANAAATSMVTLQQRQIHKVRIQRQQHQAI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . * : :: .. . * * * :. * :* .*. . . **. :: * :* . *:. : .* : . ***. . : .. * * :.::.:.: . .: .:* . : :: : : ::: . : .*: **. .. :. *. . . . * : *: .*:: . : . : :.* :: . :*: : ..: ::* * :::.:*:: :** ****:**** :: ** ******:****:* .*:: *: :*.:.******: :. ******::** :*.*::**. * : .. :*:**:****::.*:.:****:::***:* ..**:*** .********* *.**.*. *::***.**:********:***********.* ***:***:***:**:*.*******:******::* *. : **::**: **:*:*****: :** : : :* ** **.*. ", "identical_positions": 183, "similar_positions": 173, "identity": "19.85%" }, { "cls_id": "homologset.agr.FB:FBgn0004885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M280-1", "uniprot_id": "F1M280_RAT", "id": "F1M280-1", "name": "Metalloendopeptidase", "aln": "----------------------------------------------------MPQATALG----TLV-LLLLLPLLLRAEVTGDHSDVALDYGALEGEEGTEQEQQLQY-------------------------------------HDPCKAAVFWGDIALDEDD------------------------------------------------------------------------------------------------------------------------------------------------LKLFHIDKAEDWTKPSMER----------------------------------------------------------------------------------------------------------------MGHDTGGLEETSAR-WPNDTASNSSIQALRKDGKDSTTLLPGPGTSNT--------------------TAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFIERTDEES--FIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTSGNFSAPGFPNG---YPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVEIRDGYWRKAPLLGRFCGDKVPEPLVSSDSRLWVEFRSSSSILG-KGFFAVYEAMCGGDITKD--AGQIQSPNYPDDYRPSKECVWRITVADGFHVGLTFQSFEIERHDSCAYDYLEIRDGPTEESALIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAASFFKEVDECSWPDHGGCEQRCVNTLGSYTCACDPGYELAANKKTCEVA-CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPMQYRISLQFEAFELEG----NDVCKYDFVEVRSGLSPD-AKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEVEQHQECAYDHLELYDGTDSSAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSQAHCDWVIVAEDGYGVELVFRTFEVEEEADCGYDYLEAYDGYD----SSAPRLGRFCGSGPLEEIYSAGDSLMIHFHTDDTINKKGFHARYTSTKFQDALHMRK---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVM6-1", "uniprot_id": "TLL2_MOUSE", "id": "Q9WVM6-1", "name": "Tolloid-like protein 2", "aln": "----------------------------------------------------MPLATTLG----TLV-LLLLLPLPRGAEVTGDHSNVALDYGALEGEEGT--EQQLHY-------------------------------------HDPCKAAVFWGDIALDEDD------------------------------------------------------------------------------------------------------------------------------------------------LKLFHIDKAEDWTKPSIDK----------------------------------------------------------------------------------------------------------------PGHDTGGLEETSAR-WPNDTASNASIQAPRKDGKDATTFLPNPGTSNT--------------------TAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTDEES--FIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNG---YPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVEIRDGYWRKAPLLGRFCGDKIPESLVSSDSRLWVEFRSSSSSLG-KGFFAVYEAMCGGDITKD--AGQIQSPNYPDDYRPSKECVWRITVPDGFHVGLTFQSFEIERHDSCAYDYLEIRDGPTEDSTLIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEQRCVNTLGSYTCACDPGYELAADKKTCEVA-CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPVQYRISLQFEAFELEG----NDVCKYDFVEVRSGLSPD-AKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEIEQHQECAYDHLELYDGTDSLAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGYDFMEAYDGYD----SSAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYTSTKFQDALHMRK---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6L7-1", "uniprot_id": "TLL2_HUMAN", "id": "Q9Y6L7-1", "name": "Tolloid-like protein 2", "aln": "----------------------------------------------------MPRATALG----ALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGT-EQQLEHY-------------------------------------HDPCKAAVFWGDIALDEDD------------------------------------------------------------------------------------------------------------------------------------------------LKLFHIDKARDWTKQTVGA----------------------------------------------------------------------------------------------------------------TGHSTGGLEEQASESSPDTTAMDTGTKEAGKDGRENTTLLHSPGTLHA--------------------AAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTDEES--FIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNG---YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKD--AGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVA-CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG----NDVCKYDFVEVRSGLSPD-AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYD----SSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQDALHMKK---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M798-1", "uniprot_id": "F1M798_RAT", "id": "F1M798-1", "name": "Metalloendopeptidase", "aln": "----------------------------------------------------MPGVARPPLPLLSLP-LLLLLLLPR-AGRPLDLADYTYDLGEEDA------PELLNY-------------------------------------KDPCKAAAFLGDIALDEED------------------------------------------------------------------------------------------------------------------------------------------------LRAFRVQQAAVLRQQTAQR----------------------------------------------------------------------------------------------------------------SSIKAA--GNSSALGRQSTSGQPQRGSRGRWRSR----------------------------------------PRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDS--YIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG---YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKD--NGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG----NDVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYD----STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98063-1", "uniprot_id": "BMP1_MOUSE", "id": "P98063-1", "name": "Bone morphogenetic protein 1", "aln": "----------------------------------------------------MPGVARPPLPLLSLPLLLLLLLLPR-AGRPLDLADYTYDLGEEDA------PELLNY-------------------------------------KDPCKAAAFLGDIALDEED------------------------------------------------------------------------------------------------------------------------------------------------LRAFQVQQAAVLRQQTARR----------------------------------------------------------------------------------------------------------------PSIKAA--GNSSALGGQGTSGQPQRESRGRWRGR----------------------------------------PRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDS--YIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG---YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKD--NGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG----NDVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYIELFDGYD----STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13497-1", "uniprot_id": "BMP1_HUMAN", "id": "P13497-1", "name": "Bone morphogenetic protein 1", "aln": "----------------------------------------------------MPGVAR-------LPLLLGLLLLPR-PGRPLDLADYTYDLAEEDD------SEPLNY-------------------------------------KDPCKAAAFLGDIALDEED------------------------------------------------------------------------------------------------------------------------------------------------LRAFQVQQAVDLRRHTARK----------------------------------------------------------------------------------------------------------------SSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGR----------------------------------------SRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDS--YIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG---YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKD--YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG----NDVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYD----STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z8U5-1", "uniprot_id": "D3Z8U5_RAT", "id": "D3Z8U5-1", "name": "Metalloendopeptidase", "aln": "----------------------------------------------------MGLQALSPRM-LLWLVVSGIVFSRELWVCTGLDYDYTFDGNEEDK------TEPIDY-------------------------------------KDPCKAAVFWGDIALDDED------------------------------------------------------------------------------------------------------------------------------------------------LNIFQIDRTIDLTQGPFGK----------------------------------------------------------------------------------------------------------------LGHITGGFGDHGMPKKRGALYQLIDRIRRIGSGLEQNNTTKGKAPPKL--------------------SEQNEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTERSDEES--YIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESSGNLSSPGFPNG---YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIRKN--EGQIQSPNYPDDYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYDHLEVRDGNSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKADRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAA-CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVIAPSQYRISVKFEFFELEG----NEVCKYDYVEIWSGLSSE-SKLHGKFCGADVPEVITSHFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYTCQCRNGFVLHENKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWAISAIPGHRIKLAFNEFEVEQHQECAYDHLEIFDGQTEKSPILGRLCGSKIPDPLMATGNEMFIRFISDASVQRKGFQATHSTECGGRLKAERKPKDLYSHAQFGDNNYPGQLDCEWLLVSEQGSRLELSFQTFEVEEEADCGYDYVEVFDGLN----SKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSIRYPETMHAEN---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62381-1", "uniprot_id": "TLL1_MOUSE", "id": "Q62381-1", "name": "Tolloid-like protein 1", "aln": "----------------------------------------------------MGLQALSPRM-LLWLVVSGIVFSRVLWVCAGLDYDYTFDGNEEDK------TEPIDY-------------------------------------KDPCKAAVFWGDIALDDED------------------------------------------------------------------------------------------------------------------------------------------------LNIFQIDRTIDLTQSPFGK----------------------------------------------------------------------------------------------------------------LGHITGGFGDHGMPKKRGALYQLIERIRRIGSGLEQNNTMKGKAPPKL--------------------SEQSEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTERSDEES--YIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESSGNLSSPGFPNG---YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIRKN--EGQIQSPNYPDDYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYDHLEVRDGASENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAA-CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVIAPSQYRISVKFEFFELEG----NEVCKYDYVEIWSGPSSE-SKLHGKFCGADIPEVMTSHFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYTCQCRNGFVLHENKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWVISAIPGHRITLAFNEFEVEQHQECAYDHLEIFDGETEKSPILGRLCGSKIPDPLMATGNEMFIRFISDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQLDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVEVFDGLS----SKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSIRYPETMHAKN---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43897-1", "uniprot_id": "TLL1_HUMAN", "id": "O43897-1", "name": "Tolloid-like protein 1", "aln": "----------------------------------------------------MGLGTLSPRM-LVWLVASGIVFYGELWVCAGLDYDYTFDGNEEDK------TETIDY-------------------------------------KDPCKAAVFWGDIALDDED------------------------------------------------------------------------------------------------------------------------------------------------LNIFQIDRTIDLTQNPFGN----------------------------------------------------------------------------------------------------------------LGHTTGGLGDHAMSKKRGALYQLIDRIRRIGFGLEQNNTVKGKVPLQF--------------------SGQNEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEES--YIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESNGNLSSPGFPNG---YPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIRKN--EGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAA-CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEG----NEVCKYDYVEIWSGLSSE-SKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLD----STAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYPDTTHTKK---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57460-1", "uniprot_id": "TLL1_DANRE", "id": "O57460-1", "name": "Dorsal-ventral patterning tolloid-like protein 1", "aln": "--------------------------------------------------MDYLYSALTSKMNWIALLLAGLTFCCKVSVHSCLDYDDSYDYYEEEK------TETIDY-------------------------------------KDPCKAAVFWGDIALDDED------------------------------------------------------------------------------------------------------------------------------------------------LKMFHIDGTIDLKQQTHGR----------------------------------------------------------------------------------------------------------------QGHTSGGLGEHVPTKKRGSLYLLLDRIRRLGFESWPVNSSKDVSSIKTGIRR--------------VNSARNVKSRVPRAATSRAEKIWPGGVIPYVIGGNFTGSQRAMLKQAMRHWEKQTCVTFIEKTDEES--YIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVTIIRDNIQPGQEYNFIKMEPGDVNSLGEPYDFDSIMHYARNTFSRGMFLDTILPSRDENGVRPAIGQRTRLSKGDISQAKKLYRCPACGETLQDSVGNFSSPGYPNG---YPSYTHCVWRISVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKAPLLGRFCGDKIPEVLVSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEISKD--SGQIQSPNYPDDYRPSKECVWRITVSEGYSVGLSFQVFEIERHDSCAYDYLEVRDGLSENSPLIGRFCGYDKPEDIRSTSNNLWMKFVSDGTVNKAGFAANFFKEEDECLKPDNGGCEQRCVNTLGSFKCACDPGYELAPDKKSCEAA-CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISMQFEAFELEG----NEVCKYDYVEVRSGLSSD-SKLHGKYCGTEVPEVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECINTIGSYVCQCRNGFILHENKHDCKEAECEHKIHSTTGTISSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQHQECAYDHLEAFDGDSDKTPILSRLCGNKIPEPLISTGNKMYLRFISDASVQRKGFQATHSTECGGRLKAEARQKNLYSHAQFGDNNYPGHTDCEWLIVAESGYGIELTFTTFEVEEEADCGYDYIELYDGYD----TGAHKIGRFCGSGPREELYSAGDAVLIHFHSDDTISKKGFHIRYTSTKFQEALHTRK---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B1Y0-1", "uniprot_id": "A0A8M2B1Y0_DANRE", "id": "A0A8M2B1Y0-1", "name": "Metalloendopeptidase", "aln": "--------------------------------------------------------------------MNSPWTRVLVLIFCLLTVDTIYQTGPGES-------DEVDY-------------------------------------KDPCKAVAFLGDIALDEED------------------------------------------------------------------------------------------------------------------------------------------------LRFLKAHYMHATENESSGS----------------------------------------------------------------------------------------------------------------SKPDSVNRSSANRNAKDEPVLANQSILRR------------------------------------------------RRAATARPERVWPNGIIPYIISGNFTGSQRAIFKQAMRHWEKHTCVTFVERSVEES--YIVFTLRPCGCCSFVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVDIFRENIQPGQEYNFIKMEPDDVDSLGEVYDFDSIMHYARNTFSRGIYLDTMLPKYDVDGVRPPIGQRTRLSKGDIAQARKLYRCPRCGESLQDSAGNFSSPGFPNG---YAAYLHCIWRISVTPGEKIVLNFTSMDLYRSNLCWYDYVEVRDGYGRSAPLKGRICGDQLPEAIVSTDSELWIEFRSTSNWVG-KGFSAVYEAICGGEVRRD--SGQIESPNYPDDYRPNKACIWKIVVPEGFHVGLVFQSFEIEKHDNCAYDYLEVRDGDSESSPLLGRFCGYEKPDDFKSSSNQLWMKFVSDGSVNKAGFAANFFKEIDECSRPDNAHCEQRCINTLGSFHCACDPGFELAPDRRSCAAAACGGFISKLNGSFTSPGWPQEYPPNKNCVWQLIAPVQYRITLLFDAFEMEG----NDVCKYDYVEVHSGLSAD-GKLHGKFCGTEKPEAITSQLNSMSVEFKSDNTVSKRGFKAQFFSDMDECSRENGGCQHECVNTFGSYSCQCRSGFVLHSNKHDCKEVGCDQAITSVSGLITSPNWPDKYPSKKACTWTLSTTPGHRIKLAFEEIDMEAHQECAYDHLEIYDGQNGRATSVGRFCGSKKPSPVISSSNTMFLRFFSDNSVQKRGFKASHSAECGGSLKAEIKTKDLYSHAQFGDNNYPGASDCQWVISAEKGYGVELIFHTFEIEEEADCGYDYVELFDGGD----VKAPRLGRYCGSGPPEEIYSAGDAIVIKFHSDDTINKKGFHVRYTSTKFQDTLHTSK---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC47-1", "uniprot_id": "TOK_DROME", "id": "Q9VC47-1", "name": "Protein tolkin", "aln": "MRRRRGTPLGVSWTNCVLLLATGLLVVLISVHAKNPRPHRGLPAPAPAPVPASVDQVATENAHRREPTVDGSVLQRLSGSDRAVDEDEDVDEDEDEGLKHQHLEHRQQFDAYLGTIRRLRRPYRSKYTIEQLMRLHVTPKVSGDIDMDPCKAGGFMGDIALPEGDSGPVVAHTPIDDEEQERQEVEQLLADSPSPVHDPPSVSGAANSGPTKFNATFQLDLEKLKQEVYHEGLQVEEEGLTDIIRKKTKLPSSGPVNLKAGQSQSQSQSANEPVKPGSESPSDYAQASSYKNEVLPPSEQRIHTDKPARLTLAEIGPKFSNKTQSLHRNVDTRKIQSDNKDIEDDSGNNFVAERRPSQIVPTSLPEQRSTPAHVYSNAGGNGMQLDDEVDFLHSRGVVRRRHRRGPKQRRSNQHLEHEVKLQRLREELSRPVIEAHHHQSHHQKQAQHRQHHQSHHRKKHRRQQQHHRRRGQSTTQYVNHSPPGFNQSQQAQQQSVPEMDLLKAETSKDEEPLRHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHPNYIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLLYKCPKCGRTFQESSGIFASPSHYTAGALSNETEHCEWRITATYGERVELKLENMNIFKSNNCETDYLEIRDGYFEKSPLIGRFCGKVDKEVIRTESSRMLLTYVNTHRIEGFRGFKAEFDVVCGGELSVDDAVGRLESPNYPLDYLPNKECVWKITVPESYQVALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGVFCGYKPPPNMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECETQNHG-CEHECINTLGGYECSCRIGFELHSDKKHCEDA-CGGVIEYPNGTITSPSFPEMYPLLKECIWEIVAPPKHRISLNFTHFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDIDECAVNNGGCQHECRNTIGSYICMCHNGYSMHENGHDCKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIFNEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPDNSYVQLIFLTFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYCGNVLPQDINSMTHSLLVRFKTDGSVPMKGFSASYVAVPNSGEYDHSDEDVENSYSSEMVTPFPGSLKSIYIEDTQEETDEYSDFSGNQLVFNGQYRGRYSLPKRYYSGKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . .: ***** * ***** : * * . . . **.*:: *::* *:**: *.***:* ::*::: ******: **:.* *: * :***: *.*****:**:**.********:********.******:***********: ** * ::** **:*** :. :*.*** **:************:* :***::* . :* **** ***:***:**. **:** **.::*:: * :::* . .. ** **::.* **:: *:: .:::::* * **:*:***: ..:** **:** : : .*.: : : .: * :** * ::. ***:: : *:::***** ** * * *:*:* *.:.: *.* ** **:*.**.*.**::*:*** :.: *:* :***. * .:*:.. :::***** :::****:. *:** *** :.. **:.*:****.: *:* *:** .::: * * ***.: **::*:*.:*: ** *:*:*:::** ::**:: * *: ** :. * ** * : * : * * :**:. * . **. * : :**:**:::.: ** * **:* ***: :*****::* **:*** * *:.*: :*.* ***** * : : * : ***:**.**.. *.* : : .***:.: * *:::* : **:**:: :** :. :.*:**.* * * ::.. ::: : :* . *:.** * *:: *** ::* : :::****:**:::* . *:* : : . ::* * **::*.. :* :*::: :.. . . *::**. ::: * . :::*::*.:: *** * : . . ", "identical_positions": 368, "similar_positions": 291, "identity": "25.1%" }, { "cls_id": "homologset.agr.FB:FBgn0004888", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13086-1", "uniprot_id": "SUCA_RAT", "id": "P13086-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MTAAVVAAAATATMVSGSSGLAAARLLSRTFLLQQNGIRHGSYTASRKNIYIDKNTKVICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGKKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHKLTRQGKTRLIGPNCPGIINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHN-SGPKAKPVVSFIAGITAPPGR--RMGHAGAIIAGGKGGAKEKISALQSAGVIVSMSPAQLGTCMYKEFEKRKML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUM5-1", "uniprot_id": "SUCA_MOUSE", "id": "Q9WUM5-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MTATVVAAAATATMVSSSSGLAAARLLSRTFLLQQNGIRHGSYTASRKHIYIDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHRLTRQGTTRLIGPNCPGVINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTDFIDCLEVFLNDPATEGIILIGEIGGHAEENAAAFLKEHN-SGPKAKPVVSFIAGITAPPGR--RMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53597-1", "uniprot_id": "SUCA_HUMAN", "id": "P53597-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "MTATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHN-SGPNSKPVVSFIAGLTAPPGR--RMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94522-1", "uniprot_id": "SUCA_DROME", "id": "Q94522-1", "name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "aln": "------MAASMRALLKVRDGFVAG--------VRCN----SQYNKTRGNLKLNGDSRVICQGFTGKQGTFHSQQALEYGTKLVGGISPKKGGTQHLGLPVFASVAEAKKATDPHATVIYVPPPGAAAAIIEALEAEIPLIVCITEGVPQHDMVKVKHALISQSKSRLVGPNCPGIIAPE-QCKIGIMPGHIHKRGKIGVVSRSGTLTYEAVHQTTEVGLGQTLCVGIGGDPFNGTDFIDCLEVFLKDPETKGIILIGEIGGVAEEKAADYLTEYN-SGIKAKPVVSFIAGVSAPPGR--RMGHAGAIISGGKGGANDKIAALEKAGVIVTRSPAKMGHELFKEMKRLELV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53598-1", "uniprot_id": "SUCA_YEAST", "id": "P53598-1", "name": "Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial", "aln": "---MLRSTVSKASLKICRHFHRES----------------IPYDKTIKNLLLPKDTKVIFQGFTGKQGTFHASISQEYGTNVVGGTNPKKAGQTHLGQPVFASVKDAIKETGATASAIFVPPPIAAAAIKESIEAEIPLAVCITEGIPQHDMLYIAEMLQTQDKTRLVGPNCPGIINPATKVRIGIQPPKIFQAGKIGIISRSGTLTYEAVQQTTKTDLGQSLVIGMGGDAFPGTDFIDALKLFLEDETTEGIIMLGEIGGKAEIEAAQFLKEYNFSRSKPMPVASFIAGTVAGQMKGVRMGHSGAIVEGSGTDAESKKQALRDVGVAVVESPGYLGQALLDQFAKFK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: . * : :: : ::::* ***********:. : ****::*** .* *.* *** *** :* :* : *.. *:.*:**** ***** *:::***** ******:**:**: : . * * .:**:******:* * : :*** * :*.: *:**::***********:***:..***:* :*:***.* **:***.*.:**:* *:**:::***** ** :** :*.::* * :. **.***** * : ****:***: *. .*:.* **...** * **. :* : .:: : : ", "identical_positions": 152, "similar_positions": 91, "identity": "43.43%" }, { "cls_id": "homologset.agr.FB:FBgn0004889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00005-1", "uniprot_id": "2ABB_HUMAN", "id": "Q00005-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform", "aln": "-----------------------------------------------MEEDIDT------RKINNSFLRDH----SYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSER----------------DKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFD------------------------------------------------RNTKRDVTLEASRENSKP------------------RAILKPRKVCVGGKRR--------KDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWR4-1", "uniprot_id": "2ABB_MOUSE", "id": "Q6ZWR4-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform", "aln": "-----------------------------------------------MEEDIDT------RKINNSFLRDH----SYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSER----------------DKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFD------------------------------------------------RNTKRDVTLEASRENSKP------------------RAILKPRKVCVGGKRR--------KDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36877-1", "uniprot_id": "2ABB_RAT", "id": "P36877-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform", "aln": "-----------------------------------------------MEEDIDT------RKINNSFLRDH----SYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSER----------------DKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTAKVWDLNMENRPVETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFD------------------------------------------------RNTKRDVTLEASRENSKP------------------RAILKPRKVCVGGKRR--------KDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG02-1", "uniprot_id": "2ABG_MOUSE", "id": "Q8BG02-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "-----------------------------------------------MGEDTDT------RKINHSFLRDH----SYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRTFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97888-1", "uniprot_id": "2ABG_RAT", "id": "P97888-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "-----------------------------------------------MGEDTDT------RKINHSFLRDH----SYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T4-1", "uniprot_id": "2ABG_HUMAN", "id": "Q9Y2T4-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "-----------------------------------------------MGEDTDT------RKINHSFLRDH----SYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P1F6-1", "uniprot_id": "2ABA_MOUSE", "id": "Q6P1F6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "-----------------------------------------------MAGAGGG------NDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISER----------------DKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFD------------------------------------------------RNTKRDITLEASRENNKP------------------RTVLKPRKVCASGKRK--------KDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63151-1", "uniprot_id": "2ABA_HUMAN", "id": "P63151-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "-----------------------------------------------MAGAGGG------NDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISER----------------DKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFD------------------------------------------------RNTKRDITLEASRENNKP------------------RTVLKPRKVCASGKRK--------KDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36876-1", "uniprot_id": "2ABA_RAT", "id": "P36876-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "-----------------------------------------------MAGAGGG------NDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISER----------------DKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFD------------------------------------------------RNTKRDITLEASRENNKP------------------RTVLKPRKVCASGKRK--------KDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BG80-1", "uniprot_id": "A2BG80_DANRE", "id": "A2BG80-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "aln": "-----------------------------------------------MAGAGGGG-----NDVQWCFSQVKGAIDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQETENKSQPQCRSEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISER----------------DKRPEGYNLKEEDGRYRDASTITTLRVPVFRPMDLMVEASPRRVFANAHTYHINSISVNSDNETYLSADDLRINLWHLEITDRSFNIVDIKPANMEDLTEVITAAEFHPHQCNTFVYSSSKGTIRLCDMRASALCDKHSKLFEEPEDPSNRSFFSEIISSISDVKFSHNGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGNDSVVMTGSYNNFFRMLD------------------------------------------------RTQRRDVTLEASRESCKP------------------RQVLKPRRVCAGGKRK--------KDEISVDSLDFNKKILHTAWHPQENIIAVATTNNLYIFQEKVN----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q925E7-1", "uniprot_id": "2ABD_MOUSE", "id": "Q925E7-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGAGGGGCPAGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RNTRRDVTLEASRENSKP------------------RASLKPRKVCTGGKRK--------KDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56932-1", "uniprot_id": "2ABD_RAT", "id": "P56932-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGAGGGGCPTGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHHVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RNTRRDVTLEASRENSKP------------------RASLKPRKVCSGGKRK--------KDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66LE6-1", "uniprot_id": "2ABD_HUMAN", "id": "Q66LE6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGAGGGGCPAGGNDFQWCFSQVKGAIDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKSRPHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMESRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RDTRRDVTLEASRESSKP------------------RASLKPRKVCTGGKRR--------KDEISVDSLDFNKKILHTAWHPVDNVIAVAATNNLYIFQDKIN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY64-1", "uniprot_id": "2ABD_DANRE", "id": "Q6NY64-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGVGGG------NDFQWCFSQVKGAIDEDVAEADIISTVEFNYSGELLATGDKGGRVVIFQREQESKNRPLSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITSLRVPVLMPMDLMVEASPRRIFANAHTYHINSISVNSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAECHPHQCNVFVYSSSKGTIRLCDMRAAALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RNTRRDITLEASRESSKP------------------RAMLKPRKVCTGGKRK--------KDEISVDSLDFNKKILHTAWHPKENVIAVAATNNLYIFQDKMN----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36872-1", "uniprot_id": "2ABA_DROME", "id": "P36872-1", "name": "Protein phosphatase PP2A 55 kDa regulatory subunit", "aln": "MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKGALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSER----------------DKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFD------------------------------------------------RNSKKDVTLEASRDIIKP------------------KTVLKPRKVCTGGKRK--------KDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDKF-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ACD6B5I6-1", "uniprot_id": "A0ACD6B5I6_DANRE", "id": "A0ACD6B5I6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "aln": "-------------------------------------------------------------MLSPVLCSDLAALEPEYTDADVISTVEFNQTGEFLATGDKGGRVVIFQREP--------LGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPPHNPAHFLLTTNDKTVKLWKVSER----------------DKRAEGYNLRDEEGRLKDLSTITTLQVPVLRPMDLLVEASPRRVFANAHAYHINSISVNSDCETYLSADDLRINLWHLSITDRSFNIVDLKPENMEDMSEVITVAEFHPHHCHLLAFSSSTGTTRLCDMRARALCDQHAKLFEEAVDPTRRSFFSEIVSSVSDVKFSHSGRYLLTRDYLTVKVWDLNMENKPVEVYQVHDYLRTKLCSLYESDCIFDKFECAWNGTDSVIMTGAYNNYFRMFD------------------------------------------------RASRRDVTLEASREVCKR------------------RAVLQPRRVCVGKKRK--------ETDVSVDSLDFRKKILHTAWHPKENIIAIAASNNLYIFQDRLTPNGHHNTPEIQSAPPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00362-1", "uniprot_id": "2ABA_YEAST", "id": "Q00362-1", "name": "Protein phosphatase PP2A regulatory subunit B", "aln": "-----------------------------------------------MAQNNFD------FKFSQCFGDKA---DIVVTEADLITAVEFDYTGNYLATGDKGGRVVLFERSNS------RHCEYKFLTEFQSHDAEFDYLKSLEIEEKINEIKWLRPTQRSHFLLSTNDKTIKLWKVYEKNIKLVSQNNLTEGVTFAKKGKPDNHNSRGGSVRAVLSLQSLKLPQLSQHDKIIAATPKRIYSNAHTYHINSISLNSDQETFLSADDLRINLWNLDIPDQSFNIVDIKPTNMEELTEVITSAEFHPQECNLFMYSSSKGTIKLCDMRQNSLCDNKTKTFEEYLDPINHNFFTEITSSISDIKFSPNGRYIASRDYLTVKIWDVNMDNKPLKTINIHEQLKERLSDTYENDAIFDKFEVNFSGDSSSVMTGSYNNNFMIYPNVVTSGDNDNGIVKTFDEHNAPNSNSNKNIHNSIQNKDSSSSGNSHKRRSNGRNTGMVGSSNSSRSSIAGGEGANSEDSGTEMNEIVLQADKTAFRNKRYGSLAQRSARNKDWGDDIDFKKNILHFSWHPRENSIAVAATNNLFIFSAL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::**:*: ***: *: ***********:*::. **.. : ****:.***************:*:** : **:*****:****: *: * * ... * : : :*::* . :: .:*:* ::*.*:*******:*** **::**********:: : ::*:****:** ***:::**** :* ** *: : :***.*: :***** :***.::* *** :* :.**:** **:**:*:* .***: :****: *:**::*: :*::. :*: *: :*.. **.*.****** :.* .* :***:*** * : * :: : .* : : . *:. :.. ** . . * :** *:*** :*** :. **:*::***:**. ", "identical_positions": 187, "similar_positions": 123, "identity": "30.86%" }, { "cls_id": "homologset.agr.FB:FBgn0004892", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K011-1", "uniprot_id": "OSR1_RAT", "id": "B0K011-1", "name": "Protein odd-skipped-related 1", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLP----TVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLMDAR-----------------------------------------------------FQLPAFPWFPHVIHPKPEITAG-GSGAALKTKPRFDFANLALAATQEDPTK-----LGRGEGPGSPAGGLGALLDVTKLS-PEKKPTRGRLPS--------------------------------------KTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVK-----ELKTSKIKC---------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVG7-1", "uniprot_id": "OSR1_MOUSE", "id": "Q9WVG7-1", "name": "Protein odd-skipped-related 1", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLP----TVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGAVSSLMDAR-----------------------------------------------------FQLPAFPWFPHVIHPKPEITAG-GSGAALKTKPRFDFANLALAATQEDPTK-----LGRGEGPGSPAGGLGALLDVTKLS-PEKKPTRGRLPS--------------------------------------KTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVK-----ELKTSKIKC---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAX0-1", "uniprot_id": "OSR1_HUMAN", "id": "Q8TAX0-1", "name": "Protein odd-skipped-related 1", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLP----TVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGTVSSLVDAR-----------------------------------------------------FQLPAFPWFPHVIQPKPEITAG-GSVPALKTKPRFDFANLALAATQEDPAK-----LGRGEGPGSPAGGLGALLDVTKLS-PEKKPTRGRLPS--------------------------------------KTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVK-----ELKTSKIKC---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJQ7-1", "uniprot_id": "OSR1_DANRE", "id": "Q5XJQ7-1", "name": "Protein odd-skipped-related 1", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKTLPAPVPLHPSLQLANYSFLQTSNGL-----HLPADHMPSIYSFSALHAVHLHQWTLGYPPFTLPRCTFSKLPG----LVDAR-----------------------------------------------------FPLPSIPLFPHLVQPAKQESSGPGSGASSKSKPRFDFANLAAAATQDDALKA--EDLSTNNG-HVRSPSLGCLLDVAKLSSPERKPSRGRLPS--------------------------------------KTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQVK-----ELKPAKIK----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N2R0-1", "uniprot_id": "OSR2_HUMAN", "id": "Q8N2R0-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKALPAPIPLHPSLQLTNYSFLQAVNTF-----PATVDHLQGLYGLSAVQTMHMNHWTLGYPNVHEITRSTITEMAAAQGLVDAR-----------------------------------------------------FPFPALPFTTHLFHPKQGAIAHVLPALH-KDRPRFDFANLAVAATQEDPPK-------MGDLSKLSPGLGSPISGLSKLT-PDRKPSRGRLPS--------------------------------------KTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHTPRQDF-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZD1-1", "uniprot_id": "OSR2_MOUSE", "id": "Q91ZD1-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKALPAPIPLHPSLQLTNYSFLQAVNTF-----PAAVDHLQGLYGLSAVQTMHMNHWTLGYPSVHEITRSTITEMAAAQGLVDAR-----------------------------------------------------FPFPSLPFATHLFHPKQGAIAHVLPALH-KDRPRFDFANLAVAATQEDPPK-------MGDLSKLSPGLGSPISGLSKLN-PDRKPSRGRLPS--------------------------------------KTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHTPRQNF-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY34-1", "uniprot_id": "OSR2_RAT", "id": "Q6AY34-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKALPAPIPLHPSLQLTNYSFLQAVNTF-----PAAVDHLQGLYGLSAVQTMHMNHWTLGYPNVHEITRSTITEMAAAQGLVDAR-----------------------------------------------------FPFPALPFATHLFHPKQGAIAHVLPALH-KDRPRFDFANLAVAATQEDPPK-------MGDLSKLSPGLGSPISGLSKLT-PDRKPSRGRLPS--------------------------------------KTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTS---SPTAASSAAKCSG--------------ETVICGGTA--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q567J8-1", "uniprot_id": "OSR2_DANRE", "id": "Q567J8-1", "name": "Protein odd-skipped-related 2", "aln": "----------------------------------------------------------------------------------------------------------------------MGSKTLPAPVPLHPAPQLN-YSLLRTLNAF-----PVAVDQ---LYGLSALHTVQMNRWTVGFP--------------QLQGLADPR-----------------------------------------------------FPG-ALPFPAAAAH----LLPHKHPVHR-KDRPRFDFANLAVAATQEDPP----------------------VTGQSRLS-PERRPARGRLPA--------------------------------------KSKKEFICRFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHLQTS---SLSAAAAAGRCFG--------------ATATCGATV--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQS7-1", "uniprot_id": "SOB_DROME", "id": "Q9VQS7-1", "name": "Protein sister of odd and bowel", "aln": "MEAVKHLSAAAAAAAAAATCSDSPAKAAASPAASSDIAEALGELKASATAAASSASKAATSKHHSNNNHKPSAAATATAAHKKSESCNSNGNKCTAATSPIGSKTSNAAMAAATATAAAATNDLAAAAAVVLSLQGTMVSSLQQAALLPANSAAAAALNLQALESYLALQRLTGKSDVFRFSNSNTGSSNSNNATTCNSSSSEADNNALPSLIDIANIELKSSCSSSSSGEPPLTAATASAAATSSPSSNNSNSTSTPTTSKCVPLPSIGTVSAAVAAAAAAAAAAASQQAALDCATAAELAAECDLPLLDGEDALSFEAGDLDSSYGSFMFNPSAFSQAETDSALHSLQATMYQDKMSVISGAAGGVGAGAVGGLEEAGSSAAAAAAQRSKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCAECGKGFCQSRTLAVHKILHMEESPHKCPVCNRSFNQRSNLKTHLLTHTDIKPYNCASCGKVFRRNCDLRRHSLTHNLSAGVGGVVGGNLSDPFGSGSSSSSELGLPTGSASTAASSRDLVAVSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: *.*. .: : * * *: : . : : . *:: : : .. :. :. ..* . . . . :. :* *. * *:: * : . : :. .: .: * : ::**:*:*:**.*:********************:**** ************************ **************** ** : . : : ", "identical_positions": 86, "similar_positions": 58, "identity": "14.88%" }, { "cls_id": "homologset.agr.FB:FBgn0004893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K011-1", "uniprot_id": "OSR1_RAT", "id": "B0K011-1", "name": "Protein odd-skipped-related 1", "aln": "MGSKTLP--------APVPIHPSLQLTNYSFLQAVNGLPT--------------------------------------------VPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLP---RSSFSKVPGAVSSLMDARFQLPAFPWFPHVIHPKPEITAGGSGAALKTKPRFDFANLALA--ATQEDPTKLGRGEGPGSPAGGLGALLDVTKLSP------EKKPTRGR-LPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVK-----ELKTSKIKC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TAX0-1", "uniprot_id": "OSR1_HUMAN", "id": "Q8TAX0-1", "name": "Protein odd-skipped-related 1", "aln": "MGSKTLP--------APVPIHPSLQLTNYSFLQAVNGLPT--------------------------------------------VPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLP---RSSFSKVPGTVSSLVDARFQLPAFPWFPHVIQPKPEITAGGSVPALKTKPRFDFANLALA--ATQEDPAKLGRGEGPGSPAGGLGALLDVTKLSP------EKKPTRGR-LPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVK-----ELKTSKIKC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AY34-1", "uniprot_id": "OSR2_RAT", "id": "Q6AY34-1", "name": "Protein odd-skipped-related 2", "aln": "MGSKALP--------APIPLHPSLQLTNYSFLQAVNTFP---------------------------------------------AAVDHLQGLYGLSAVQTMHMNHWTLGYPNVHEI---TRSTITEMAAAQGLVDARFPFPALPFATHLFHPKQGAIAHVLPALHKDRPRFDFANLAVA--ATQEDPPKMGDLSKLSPGLG--SPISGLSKLTP------DRKPSRGR-LPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTS---SPTAASSAAKCSG--------------ETVICGGTA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZD1-1", "uniprot_id": "OSR2_MOUSE", "id": "Q91ZD1-1", "name": "Protein odd-skipped-related 2", "aln": "MGSKALP--------APIPLHPSLQLTNYSFLQAVNTFP---------------------------------------------AAVDHLQGLYGLSAVQTMHMNHWTLGYPSVHEI---TRSTITEMAAAQGLVDARFPFPSLPFATHLFHPKQGAIAHVLPALHKDRPRFDFANLAVA--ATQEDPPKMGDLSKLSPGLG--SPISGLSKLNP------DRKPSRGR-LPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRHSLTHTPRQNF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q567J8-1", "uniprot_id": "OSR2_DANRE", "id": "Q567J8-1", "name": "Protein odd-skipped-related 2", "aln": "MGSKTLP--------APVPLHPAPQLN-YSLLRTLNAFP---------------------------------------------VAVDQ---LYGLSALHTVQMNRWTVGFP-----------------QLQGLADPRFPG-ALPFPAAAAH----LLPHKHPVHRKDRPRFDFANLAVA--ATQEDPP-----------------VTGQSRLSP------ERRPARGR-LPAKSKKEFICRFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHLQTS---SLSAAAAAGRCFG--------------ATATCGATV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQU9-1", "uniprot_id": "BOWEL_DROME", "id": "Q9VQU9-1", "name": "Protein bowel", "aln": "MPTESSSSEISGGGGGAIPMLRPSRMDQFMNSMAAAAAAVGGGGLPGAADRNGGSGGSDGGSQNGNGDSRNSSASRISAYETQLAYQQHLAGLHGPPPPPPPSHHREISAFVPVLPTGKVRPGSNSNYEIIAMMADKRKELALREAAAAAAMLGRGPGGPGGPGVPPPGVLYGPAGVPPPPYLTGPGPSPTGAGSFPFPPGAAAAALFPPG-LGPGMHAGLDRRLLRAPGRASRPKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLKTHLLTHTDHKPYECSSCGKVFRRNCDLRRHALTHAVGEVNSGDYVDVGEEDEARNLSGDEEDSLLEVDSPRQSPVHNLGESGGSGEKSESERMRLKRKAAIDHEESEEEFDDFDEEEELQDLPRVHDLPREEDDDFDPEDEEQAEVALVARFQASKAAATSQSSSSVGTKPERQGVTHCHHEGGETYTMRPHGEKHQEEPGNSGIASLPVPPSFVRYSVPPGAAGPPPAPPGAPPPTHQHPGHPHLLPPNGDPYLPILHVRRDLHHKSLNLSKAGVPPPPHTPPTIITQPESGKPPNQPLHSPHEAMPSFLGSIPMRKRILPAPTLDLMDPHHHPGLGQRTFVDSPSIYALNMSRHPPRQLLGKPPSTETSGATTEKGPPVAAPPIAPPPAPPRRTGFSIEDIMRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: . ..:*: . :: : : . . :: *:* .. . :: .: : * * . :. *.:. . * .*. : * * ::: *. .::.**:*:*:**.*:********************:**** ************************ **************** ** : . : : ", "identical_positions": 85, "similar_positions": 54, "identity": "11.41%" }, { "cls_id": "homologset.agr.FB:FBgn0004895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "--MSVTSREQK-----FSGKYSS--YTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDW---------TYYVQKLEVTIGRNTDSLNLNAVPGTVVKKN---IDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHT----PLSSSSDVNPIGDPHGDTIMMEEDEE------DENYTRGGIRPNTYTSSSNN-----------------AVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGS--ISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKF-----------------------------------------------GEIPAPESS----------------------------------------------------------------SIDPRGIKAQKVKKS---------------------------------------LQATSSILGESAPQLQRTQLTG--------QISTTTS-------------------------------------------------MDVTTNANVNNSSLS--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41813-1", "uniprot_id": "FKH2_YEAST", "id": "P41813-1", "name": "Fork head protein homolog 2", "aln": "--MSSSNFNEMNELNMTQTNYGSTKYTAQHHQGVINAIISSLTAPDQPTTVSLQYSNDKNMATEIQAYAKLSGPNW---------TYYVKDLEVSIGRNTDPLNSALQENSDGVKNSYRVNIDLGPAKVVSRKHAIIKYNMNIGGWELHILGRNGAKVNFQRTHNGPNNPPIRLSSGTLLDIGGTQMMFILPDSDPVVAPICIEHLMPNLINMFGLEGNNNPLLRDIIKQSNYAKQRQLTSNQQIKGFKLYGSGGNAPFGSGANLGPSEQGIFNNNNNSKNKNGYFTSINPNYTASTTTSNTINPQAASPQGPPNTIIAANFVDSYKSSNAYPQALDFTSDLSHDENRNVKPPHSYATMITQAILSSPEGV--ISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRISESYQQEFLNKWNTGKVGKIRRGSSVARQLQLHMAKFNSLPMEMDYRLSLNMAQPPKRQLQSHNVLEPSNNNIIEGFVQHVPSKGNLPASQQSQPPVSHQNQSQQPPPQEQRQEIQFTFADTQNRNIALARPIKTPQLQAPNSNANLNQNNMKEYKESLHPPAISISQMNRQSPNNALVSFTNACANSKIINNISDSADKSTNNNGGTKMNLPAISTSSLDENGNLEPTTTTSSGNSNSVPQTGTTTSSLAANSLRLSQPYDTLLRSPTKAFHITAMEAYTPERGSANRARSPLHSNSNNTNNNGANNSNLQTSGMENKQTGLVLDSNVLKSMESNNDNRRLTPSTSKSQNVKSSPGVWNLLQFSSTNNTPAADSGGNKRGFSINPDIKAKENENATSEKDSDSNSNDLETKDINSSPLKNQGGSTANAKELILDTDGAKISIINN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q64731-1", "uniprot_id": "FOXL1_MOUSE", "id": "Q64731-1", "name": "Forkhead box protein L1", "aln": "---------------------------------MSHLFSPPLAALAASPLLYVYSPERPGLPLAFAPAAALAGPGR---------VEPPQKPPYSYIALIAMAIQDAPEQRVTLN---------GIYQFIMDRFPFYHDNRQ--GWQNSIRHNLSLNECFVKVPREKGRP-------------GKGSYWTLDPR-------CLDMFE---------NGNYRRRKRKPKPAAGSPEAKRTRVEPPE-------------SEVGCDVGSPDLATALPTRAPDRSQ--------SPAVGTARPALLPWPGPE-------------------PRDPDADLTVQGAGAVASGQLQRPAHHLGSPLCPAPSGSPKGS-KSKSFSIDSILAVR--PTPASGAEAPGIPKPVPG-ALGSSLLAASSGLAPPFNASLVFDAHVQGGFSQLGIPFLSYFPLQVPEATVLRFH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12952-1", "uniprot_id": "FOXL1_HUMAN", "id": "Q12952-1", "name": "Forkhead box protein L1", "aln": "---------------------------------MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGR---------AETPQKPPYSYIALIAMAIQDAPEQRVTLN---------GIYQFIMDRFPFYHDNRQ--GWQNSIRHNLSLNDCFVKVPREKGRP-------------GKGSYWTLDPR-------CLDMFE---------NGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAE-------AQPEAGSGAGGSGPAISRLQAAPAGPS--------PLLDGPSPPAPLHWPGTA-------------------SPNEDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPD-TVLHFQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02360-1", "uniprot_id": "FOXL1_DROME", "id": "Q02360-1", "name": "Fork head domain-containing protein L1", "aln": "MLPSCYANGSMLPDNEELVNSMLANPDYLRTQVSPNPLAPSAVGGAGMEGLMCGSFSPAFYYQGIDSFLALHNNIWGLPISFLHNSHRPEKPPFSYIALIAMAISSAPNQRLTLS---------GIYKFIMDKFPYYRENKQ--GWQNSIRHNLSLNDCFVKIPRDKNTIEDN-------DSAGKGSYWMLDSS-------ASDMFE---------QGNYRRRRTRRQRHCGHPNRYER--------------------ESGKDSNDGNSSAAEIRSPSEPLS---------------DFDIFCNERPN-------------------YSDRITDLHRQYLSVSLGFNSLFNNEARGLRPLPEIRECPDDVDASSSSSKAMQSSMELHEELHSPSAFTPPLNRRETSSSGAPVLAEAFN-----GIKDVVDAPGSSPVASSNRSKTTLFTIDNIIGKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . . . : :. : . * :.: :.. : * : .*: * . . : * : . * : * . : : :** . . . . . . . . . . *.. . . : . : . . :. . : : . . . : ", "identical_positions": 10, "similar_positions": 60, "identity": "1.14%" }, { "cls_id": "homologset.agr.FB:FBgn0004896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35392-1", "uniprot_id": "FOXD2_MOUSE", "id": "O35392-1", "name": "Forkhead box protein D2", "aln": "MTLGSCCCEIMSSESSPAALSEPDADIDVVGGGSGGGELTARSGPRAPRDVLPHGHEPPPEEAEADVAEDEEESGGCSDCEPRALAPRGAAAAAGSPGPGVQAARGATGPG---------PGPGPPSGGAATRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNS---------------IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLSSFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHPHAFAFAATAPCQLSVPPGRAAAPPPGPPTASVFASAASAPAPAPAPGSGPSPAG-LPAFLGAELGCAKAFYPASLSPPAAGTAASLSTAL-LRQG---LKTDAG-GGAGGGGAGTGQRPSFSIDHIMGHGGGGAAPPGSGDGSPGSPFAAAAGPGGQAQVLAMLTAPALTPVAGHIRLSHPGDSLLSSGPSFAS--KVAGLSGCHF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63251-1", "uniprot_id": "FOXD1_RAT", "id": "Q63251-1", "name": "Forkhead box protein D1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------LVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNS---------------IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02361-1", "uniprot_id": "FD3_DROME", "id": "Q02361-1", "name": "Fork head domain-containing protein FD3", "aln": "MHTST---DPMHTLHDSVSLSPP--LIKSSRGGSSIGNGIGCS-------------------ASSRTAAADAMSMGCDDSD---IEP----SSMGGSG-----AAGGNGDG---------SGS---SGG-----PLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNS---------------IRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTL----SPFWIRKPVPLVP--VHFNVPNFNGSREFDVVHNPADVFDSALRAD-KKFNFFANAEASF-YQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVAS-AAGIPGHRDYAERLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCEDKIDVESGNEQEDSHISDSVDS--ACTNRLDAPPEALIFEASAEASDSSPRRRFDSEPLVLRTSKQSSAKDFRIETLIGHHLHRGGSQEETSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q63245-1", "uniprot_id": "FOXD3_RAT", "id": "Q63245-1", "name": "Forkhead box protein D3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------LVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNS---------------IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VB84-1", "uniprot_id": "FX4L3_HUMAN", "id": "Q6VB84-1", "name": "Forkhead box protein D4-like 3", "aln": "----------MNLPRAERLRSTPQRSLRDSDGEDGKIDVLG--------------------EEEDEDEVEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNS---------------IRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPH----------------PFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAP--------VYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRICPRPRGATATCSSDHQACCIPRPLPLCCK--------CPPPP--LLGQFCSNSSSIRRR------------------------TAPTAALPPRARCWAGTCRPRRPC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3SYB3-1", "uniprot_id": "FX4L6_HUMAN", "id": "Q3SYB3-1", "name": "Forkhead box protein D4-like 6", "aln": "----------MNLPRAERLRSTPQRSLRDSDGEDGKIDVLG--------------------EEEDEDEVEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNS---------------IRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPH----------------PFPLPAAHAALHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAP--------VYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQACCIPRPLPLCCK--------CPPPP--LLGQFCSNSSSIRRR------------------------TAPTAALPPRARCWAGTCRPRRPC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WXT5-1", "uniprot_id": "FX4L4_HUMAN", "id": "Q8WXT5-1", "name": "Forkhead box protein D4-like 4", "aln": "----------MNLPRAERPRSTPQRSLRDSDGEDGKIDVLG--------------------EEEDEDEVEDEEEEARQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNS---------------IRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPH----------------PFPLPAAHAALHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAR--------VYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQACCIPKPLPLCCK--------CPPPL--LLGQFCSNSSSIRR-------------------------TAPTAALPPRARCWAGTCRPRRRC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12950-1", "uniprot_id": "FOXD4_HUMAN", "id": "Q12950-1", "name": "Forkhead box protein D4", "aln": "----------MNLPRAERLRSTPQRSLRDSDGEDGKIDVLG--------------------EEED----EDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNS---------------IRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPH----------------PFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAP--------AYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQE-EDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEG----TSPVFLVSPTPSSLAESAGPS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "----------MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLS-----------------SSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLN---AVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHT----------------PLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *: . . :: . . *:* . *: :* .:: :.* :: . *. . :* ::::..::**.:: :. ", "identical_positions": 10, "similar_positions": 38, "identity": "1.87%" }, { "cls_id": "homologset.agr.FB:FBgn0004897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64733-1", "uniprot_id": "FOXB2_MOUSE", "id": "Q64733-1", "name": "Forkhead box protein B2", "aln": "MPRPGKSS-YSDQKPPYSY------ISLTAMAIQHSAEKMLPLSDIYKFIMER-------------FPYYREHTQRWQNSLRHNLSFNDCFIKIPRR---PDQPGKGSFWALHPDCGDMFENGSFLRRRKRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHHHPPQPPPPPPP---HMVPYFHQQPAPAPQPP-HLPSQPAQQPQPQSQPPQTSHPGKMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTTGFKHPFAIEN-----------IIGRDYKGVLQAGGLPLASVMHH-LGYPVPGQLSNVVGSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAFGVPVKALCHSANQS-LPAVPVPIKPTPALPPVTTLPPALSVPTASQQLP-----APSTVC-AAAASPTAPLLEPTAAGRADSKGSSLHSVLVHS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7J9-1", "uniprot_id": "A0A0G2K7J9_RAT", "id": "A0A0G2K7J9-1", "name": "", "aln": "MPRPGKSS-YSDQKPPYSY------ISLTAMAIQHSAEKMLPLSDIYKFIMER-------------FPYYREHTQRWQNSLRHNLSFNDCFIKIPRR---PDQPGKGSFWALHPDCGDMFENGSFLRRRKRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHHHPPQPPPPPP----HMVPYFHQQPAPAPQPP-HLPSQPAQQPPPQSQPPQTSHPGKMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTTGFKHPFAIEN-----------IIGRDYKGVLQAGGLPLASVMHH-LGYPVPGQLGNVVGSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAFGVPVKALCHSANQS-LPAVPVPIKPTPALP--TTLPPALAVPTASQQLP-----APSTVC-AAAASPTAPLLEPTAAGRADSKGGSLHSVLVHS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VYV0-1", "uniprot_id": "FOXB2_HUMAN", "id": "Q5VYV0-1", "name": "Forkhead box protein B2", "aln": "MPRPGKSS-YSDQKPPYSY------ISLTAMAIQHSAEKMLPLSDIYKFIMER-------------FPYYREHTQRWQNSLRHNLSFNDCFIKIPRR---PDQPGKGSFWALHPDCGDMFENGSFLRRRKRFKVLRADHTHLHAGSTKSAPGAGPGGHLHPHHHHHP-HHHHHHHAAAHHHHHHHPPQPPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPGKMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTSGFKHPFAIEN-----------IIGRDYKGVLQAGGLPLASVMHH-LGYPVPGQLGNVVSSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAFGVPVKSLCHSASQS-LPAMPVPIKPTPALPPVSALQPGLTVPAASQQPP-----APSTVCSAAAASPVASLLEPTAPTSAESKGGSLHSVLVHS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64732-1", "uniprot_id": "FOXB1_MOUSE", "id": "Q64732-1", "name": "Forkhead box protein B1", "aln": "MPRPGRNT-YSDQKPPYSY------ISLTAMAIQSSPEKMLPLSEIYKFIMDR-------------FPYYRENTQRWQNSLRHNLSFNDCFIKIPRR---PDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDH----------------------------------------------------------------------LAPSKP----ADAAQYLQQQAKLR-------------------LSALAASG--THLPQMP------AAAYNLGGVAQPSGFKHPFAIEN-----------IIAREYK---MPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMTSG-DYSAYGVPLKPLCHAAGQT-LPAIPVPIKPTPAAVP---ALPALPAPIPTLLSN-----SPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99853-1", "uniprot_id": "FOXB1_HUMAN", "id": "Q99853-1", "name": "Forkhead box protein B1", "aln": "MPRPGRNT-YSDQKPPYSY------ISLTAMAIQSSPEKMLPLSEIYKFIMDR-------------FPYYRENTQRWQNSLRHNLSFNDCFIKIPRR---PDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDH----------------------------------------------------------------------LAPSKP----ADAAQYLQQQAKLR-------------------LSALAASG--THLPQMP------AAAYNLGGVAQPSGFKHPFAIEN-----------IIAREYK---MPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMASG-DYSAYGVPLKPLCHAAGQT-LPAIPVPIKPTPAAVP---ALPALPAPIPTLLSN-----SPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32028-1", "uniprot_id": "FD4_DROME", "id": "P32028-1", "name": "Fork head domain-containing protein FD4", "aln": "MPRPSRES-YGEQKPPYSY------ISLTAMAIWSSPEKMLPLSDIYKFITDR-------------FPYYRKNTQRWQNSLRHNLSFNDCFIKVPRR---PDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLN---------------------------------------------RFFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPN---SLGPGVPLPHVMPASMSGADHTNLADMGLTNLPALTSSEIEGPLSLR-PKRSFTIES-----------LITPDKP----EHPSEDEDDEDDRVDIDVVECSGISRYPTTPAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLHYATGANVAGLPASGIPNSPTTYELAISHPLFMMAAPIANMHNI-----YYNNVTLVAPAQQYRS---PEVQNRIDNDMRTI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ..:. :. : ..*: :. .: .: *.: : *: : : :.** :: : . ..*.:* .: :: * *. :*.** : : : : : . : . . ::::. : : * . *. . * :..* .. . :. . : ", "identical_positions": 17, "similar_positions": 69, "identity": "3.51%" }, { "cls_id": "homologset.agr.FB:FBgn0004898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64732-1", "uniprot_id": "FOXB1_MOUSE", "id": "Q64732-1", "name": "Forkhead box protein B1", "aln": "-------------------------------------MPRPGRNTYSD--------------QKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDR-----------------FPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQP------------------------------------------GKGSFWALHPSCGDMFENGSFLRRR---KRFKVLKSDH------------------------------------------------LAPSKPADAAQYLQQQ----------------------------------------AKLRLSALAASG--THLPQMP------AAAYNLGGVAQPSGFKHPFAIENIIAREYK----------MPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHV---YGSAGMIDSATPISMTSG-DYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALP-ALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99853-1", "uniprot_id": "FOXB1_HUMAN", "id": "Q99853-1", "name": "Forkhead box protein B1", "aln": "-------------------------------------MPRPGRNTYSD--------------QKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDR-----------------FPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQP------------------------------------------GKGSFWALHPSCGDMFENGSFLRRR---KRFKVLKSDH------------------------------------------------LAPSKPADAAQYLQQQ----------------------------------------AKLRLSALAASG--THLPQMP------AAAYNLGGVAQPSGFKHPFAIENIIAREYK----------MPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHV---YGSAGMIDSATPISMASG-DYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALP-ALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K7J9-1", "uniprot_id": "A0A0G2K7J9_RAT", "id": "A0A0G2K7J9-1", "name": "", "aln": "-------------------------------------MPRPGKSSYSD--------------QKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMER-----------------FPYYREHTQRWQNSLRHNLSFNDCFIKIPRRPDQP------------------------------------------GKGSFWALHPDCGDMFENGSFLRRR---KRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHHHPPQPPPPPPHMVPYFHQQPAPAPQPPHLPSQPAQQPPPQSQPPQTSHPGKMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTTGFKHPFAIENIIGRDYKGV-------LQAGGLPLASVMHH-LGYPVPGQL---GNVVGSVWPHVGVMDSVAAAAAAAAAAGVPVGPEYGAFGVPVKALCHSANQSLPAVPVPIKPTPALPTTLPPALAVPTASQQLPAPSTVCAAAASPTAPLLEP-TAAGRADSKGGSLHSVLVHS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32029-1", "uniprot_id": "FD5_DROME", "id": "P32029-1", "name": "Fork head domain-containing protein FD5", "aln": "-------------------------------------MPRPLKMSYGD--------------QKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQ-----------------FPFYRKNTQKWQNSLRHNLSFNDCFIKVPRNVTKA------------------------------------------GKGSYWTLHPMAFDMFENGSLLRRR---KRFRVKQLEKDISN-----------------------------------------WKLAAAANTEMVTHYLDDQ---------------------------------------LTQMAFADPARHG--HVLANAS------AAQMSPYKATPP---ILPTTVTQLPARPKR-------------AFTIESLMAPDPASTP-----------------------NEGLVPMEYGSPDAVALEKPPFNLPFNFNELAAQYQLYFPSFFYNGQYGNIPCYQ-----KTPPLFHNGPLPVF------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSS-------------------------------------SDVNPIGDPHGDTIMMEEDEEDENYTRG-------------------------GIRPNTYTSSSNNAVTNGNVPHIENPS------DLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *.: ::* . . * *. : ::.: :. .: *: .: . . : * ::* .. *: :* :::*..: **.: :. :: : :: . . . :.:: . * : : . . . : . .: . . : . . : * . . .. .: ", "identical_positions": 15, "similar_positions": 73, "identity": "2.72%" }, { "cls_id": "homologset.agr.FB:FBgn0004901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35433-1", "uniprot_id": "PUR1_RAT", "id": "P35433-1", "name": "Amidophosphoribosyltransferase", "aln": "-----------------------------------MELEES-------GIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPKFRVHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIG-LSTSSDSEMITQLLAYTPPQEQD---DTPDWVARIKNLMKEAPAAYSLVIMHR-DVIYAVRDPYGNRPLCIGRLMPVSDINDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGVR-TLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG-----QQLAVEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKHPCFMGINIPTKEELIANKPEFEYLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQK-VKKRDITIQENGNGLEYFEKTGHCTACLTGQYP----VDLEW----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIH9-1", "uniprot_id": "PUR1_MOUSE", "id": "Q8CIH9-1", "name": "Amidophosphoribosyltransferase", "aln": "-----------------------------------MELEEL-------GIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSAVPKFRVHKGMGLVNHVFTEDNLKKLYDSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRQGIG-LSTSSDSEMITQLLAYTPPQEKD---DAPDWVARIKNLMKEAPAAYSLVIMHR-DFIYAVRDPYGNRPLCIGRLMPVSDVNDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGIR-TLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG-----QQLAIEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDCLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQK-VKKHDIAIQENGNGLEYFEKTGHCTACLTGQYP----VELEW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06203-1", "uniprot_id": "PUR1_HUMAN", "id": "Q06203-1", "name": "Amidophosphoribosyltransferase", "aln": "-----------------------------------MELEEL-------GIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIG-LSTSSDSEMITQLLAYTPPQEQD---DTPDWVARIKNLMKEAPTAYSLLIMHR-DVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQ-TLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCG-----QQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQK-EKKHDIMIQENGNGLECFEKSGHCTACLTGKYP----VELEW----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27601-1", "uniprot_id": "PUR1_DROME", "id": "Q27601-1", "name": "Amidophosphoribosyltransferase", "aln": "MSAPQQQQQSQQKQQQHVRVVEQQQVEPAEAVTSSMESESISASKELTGLTHECGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNVHKGMGMISTLFNDDSMKKLRG-NLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGELVNNESLRREVLARGVG-LSTHSDSELIAQSLCCAPEDVSEL--DGPNWPARIRHFMMLAPLSYSLVIMLK-DKIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTP-ADGWVVSSESCGFLSIGARYVREVEPGEIVELSRSGYR-TVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTVRLQCG-----RQLWREAPVEADIVSSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPSTRLRQLGVAKKFGALSENVAGKRLVLIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPLQYPCYMGINIPTREELIANKLNPDQLARHVGADSLAYLSVEGLVEAVQLKHRDAGDS-KSKG----------------TGHCTACLTGEYPGGLPDELSW----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04046-1", "uniprot_id": "PUR1_YEAST", "id": "P04046-1", "name": "Amidophosphoribosyltransferase", "aln": "----------------------------------------------------MCGILGIVLAN---QTTPVAPELCDGCIFLQHRGQDAAGIATCGSR--GRIYQCKGNGMARDVFTQQRVSGLAG-SMGIAHLRYPTAGSSANSEAQPFYVNSPYG-INLAHNGNLVNTASLKRYMDEDVHRHINTDSDSELLLNIFAAELEKHNKYRVNNEDVFHALEGVYRLCRGGYACVGLLAGFALFGFRDPNGIRPLLFG----------ERENPDGTKDYMLASESVVFKAHNFTKYRDLKPGEAVIIPKNCSKGEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGSKLAENILKQLKPEDIDVVIPVPDTARTCALECANVLGKPYREGFVKNRYVGRTFIMPNQRERVSSVRRKLNPMESEFKGKKVLIVDDSIVRGTTSKEIVNMAKESGATKVYFASAAPAIRYNHIYGIDLTDTKNLIAYNRTDEEVAEVIGCERVIYQSLEDLIDCCKTDKITKFEDGVFTGNYVTGVEDGYIQELEEKRESIANNSSDMKAEVDIGLYNCADY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::* : .. :. : * : ******::***.*. . : ** *: :*.:: :. * .:**.* **.*:* . :.*** *.: :* : :****:*** *:: : :.* ****:: : :. . .. : : :. . . .*: : : ::..**. * *** :* :. .. :..::::*** * : . ::: *** * :.: : :: . :******** **:::. ** .* * . * * : *:* .**::. ..* * * : * : :********* *. * * .* :*:. :..:. **:::::*******.* *::: :::** :*:: *:*.::: **::. ::*** : : :*. :*.: : * *:*.*:.. : :. . . .. * :.. * ", "identical_positions": 127, "similar_positions": 164, "identity": "21.93%" }, { "cls_id": "homologset.agr.FB:FBgn0004903", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LU98-1", "uniprot_id": "A0ABK0LU98_RAT", "id": "A0ABK0LU98-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "-------------------------MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVP----KEDIHAGGGG--ARAARGGRGGGRGRGGGGGGG-----------------------------------------------------GGRDQNGLAKGGGGG---YNSYGG-YGG-----YGAYGG----------------------------------------------------------GGGGG-SYGGSDYGNGFGGFG---SYSQHQSS--YGPMKSGGGGGGGGGSWGGRSNSGPYRGGYGGGGGGGYGGGSF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX86-1", "uniprot_id": "ROA0_MOUSE", "id": "Q9CX86-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "-------------------------MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVP----KEDIHAGGGG--ARAARGGRGGGRGRGGGGGGG-----------------------------------------------------G-RDQNGLAKGGGGGGGGYNSYGG-YGG-----YGAYGG----------------------------------------------------------GGGGGGSYGGSDYGNGFGGFG---SYSQHQSS--YGPMKSGGGGGGGG-SWGGRSNSGPYRGGYGGG----YGGGSF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13151-1", "uniprot_id": "ROA0_HUMAN", "id": "Q13151-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "-------------------------MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVP----KEDIYSGGGGGGSRSSRGGRGG-RGRGGG-----------------------------------------------------------RDQNGLSKGGGGG---YNSYGG-YGGGGGGGYNAYGG----------------------------------------------------------GGGGS-SYGGSDYGNGFGGFG---SYSQHQSS--YGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGG--YGGSSF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T746-1", "uniprot_id": "A0AB32T746_DANRE", "id": "A0AB32T746-1", "name": "", "aln": "------------------------MSEMEKLCKLFVGGLNVQTTNDGLRSYFEQFGNLTDCVVVQNDQLQRSRCFGFVTYSTSEEADAAMAARPHVVDGKNVEVKRAVAREDAGRPEALAKVKKIFVGGLKDDIEEKDLTEFFSQFGMIEKSEVITDKDTGKKRGFGFVHFEDNDSADKAVVLKFHMINGHKVEVKKALT----KQEIQAAGGA------RGGRGRGGGRGMG-----------------------------------------------------------RNQNGFGGGRGGG---YGGYGGGYGGGYGGNDGGYGGS---------------------------------------------------YGSGGYGGGYGGGYGGG-YGEQMGGYGGGNGYSDFGSG--YGQQSSGYGPMKGGNTYGGRS-GAPYPRGGGGGPG--YGRGGYGGY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02926-1", "uniprot_id": "RB97D_DROME", "id": "Q02926-1", "name": "Ribonucleoprotein RB97D", "aln": "MVKDEPLSDESADVIVLADREEDDICELEHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGFITYTKSLMVDRAQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHDEECLREYFLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVKKSIYNLDKKEKQQPGGLANAIKPSLNQQQQQQGGGQQPPNGNMQAPSFRPPVPPQQAMGPYQQQPPPAPMSAPPPNFNYWGPPPPAMPPYYQQPPPQQMNGWGPYPPPQQNGWNAPPPPPPGAQQWHANQWGCPPPVQQVPPVGAVPPPMGHNGPPPTAPGNWNMPPPVPGAAPPSHQQQSSQQPTPQPNFGTGYQQNYGGGPSKHNNMNANRMNPYSAGPPNSYHTPQPPAYTGYNAGPLPPNGSVPPPTGAKAVGVSNGSVATGGSANSKYRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:* ***:*** *::..*: .: :*.:.* **: : :*** ***:**:. .* * ** :**:.** ***:.* : : .***:******.: * * *.* *** : . ::::** :**:***.** *:. *:.*** : * * *: :*:***:: *:. ..* . . : * * :: ** . :.. * . :* * * .***. . . . ** .. : .. .* . * * * . .. ", "identical_positions": 90, "similar_positions": 82, "identity": "19.11%" }, { "cls_id": "homologset.agr.FB:FBgn0004907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35213-1", "uniprot_id": "1433B_RAT", "id": "P35213-1", "name": "14-3-3 protein beta/alpha", "aln": "-MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICSDVLELLDKYLILNAT--HAESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEG-EN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQV8-1", "uniprot_id": "1433B_MOUSE", "id": "Q9CQV8-1", "name": "14-3-3 protein beta/alpha", "aln": "-MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLILNAT--QAESKVFYLKMKGDYFRYLSEVASGENKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEG-EN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31946-1", "uniprot_id": "1433B_HUMAN", "id": "P31946-1", "name": "14-3-3 protein beta/alpha", "aln": "-MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNAT--QPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEG-EN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PRD0-1", "uniprot_id": "143BA_DANRE", "id": "Q5PRD0-1", "name": "14-3-3 protein beta/alpha-A", "aln": "---MDKSDLVQKAKLAEQAERYDDMAASMKAVTEGGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--EGNEKKQQMAREYREKIEAELQEICNDVLGLLEKYLIPNAS--QAESKVFYLKMKGDYYRYLSEVASGDSKRTTVENSQKAYQDAFEISKKEMQPTHPIRLGLALNFSVFYYEILNTPEQACSLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEG-EN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T356-1", "uniprot_id": "143BB_DANRE", "id": "Q7T356-1", "name": "14-3-3 protein beta/alpha-B", "aln": "---MDKSDLVQKAKLAEQAERYDDMAAAMKAVTEGGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--EGNEKKQQMAREYREKIETELQDICSDVLGLLEKYLIANAS--QAESKVFYLKMKGDYYRYLSEVASGDSKATTVENSQKAYQDAFDISKKDMQPTHPIRLGLALNFSVFYYEILNSPENACQLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSENQGEE--AGEN-EN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63102-1", "uniprot_id": "1433Z_RAT", "id": "P63102-1", "name": "14-3-3 protein zeta/delta", "aln": "---MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63101-1", "uniprot_id": "1433Z_MOUSE", "id": "P63101-1", "name": "14-3-3 protein zeta/delta", "aln": "---MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QPESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63104-1", "uniprot_id": "1433Z_HUMAN", "id": "P63104-1", "name": "14-3-3 protein zeta/delta", "aln": "---MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29310-1", "uniprot_id": "1433Z_DROME", "id": "P29310-1", "name": "14-3-3 protein zeta", "aln": "MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT--EASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKAS--NPESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P61981-1", "uniprot_id": "1433G_HUMAN", "id": "P61981-1", "name": "14-3-3 protein gamma", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61983-1", "uniprot_id": "1433G_RAT", "id": "P61983-1", "name": "14-3-3 protein gamma", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61982-1", "uniprot_id": "1433G_MOUSE", "id": "P61982-1", "name": "14-3-3 protein gamma", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PC29-1", "uniprot_id": "143G1_DANRE", "id": "Q6PC29-1", "name": "14-3-3 protein gamma-1", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKSVTELNEALSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELETVCQDVLNLLDNFLIKNCGETQHESKVFYLKMKGDYYRYLAEVATGEKRAAVVESSEKSYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDEGGEGNN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F354-1", "uniprot_id": "E7F354_DANRE", "id": "E7F354-1", "name": "", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKSVTELNEALSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLNLLDNFLIKNCSETQHESKVFYLKMKGDYYRYLAEVATGEKRSTVVESSEKSYNEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDEGGEGNN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P68511-1", "uniprot_id": "1433F_RAT", "id": "P68511-1", "name": "14-3-3 protein eta", "aln": "--MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68510-1", "uniprot_id": "1433F_MOUSE", "id": "P68510-1", "name": "14-3-3 protein eta", "aln": "--MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04917-1", "uniprot_id": "1433F_HUMAN", "id": "Q04917-1", "name": "14-3-3 protein eta", "aln": "--MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68255-1", "uniprot_id": "1433T_RAT", "id": "P68255-1", "name": "14-3-3 protein theta", "aln": "---MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANAT--NPESKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68254-1", "uniprot_id": "1433T_MOUSE", "id": "P68254-1", "name": "14-3-3 protein theta", "aln": "---MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANAT--NPESKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27348-1", "uniprot_id": "1433T_HUMAN", "id": "P27348-1", "name": "14-3-3 protein theta", "aln": "---MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANAT--NPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V9A3-1", "uniprot_id": "G3V9A3_RAT", "id": "G3V9A3-1", "name": "", "aln": "---MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAG--EAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPEEPQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70456-1", "uniprot_id": "1433S_MOUSE", "id": "O70456-1", "name": "14-3-3 protein sigma", "aln": "---MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAG--DAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADSAGEEGGEAPEEPQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31947-1", "uniprot_id": "1433S_HUMAN", "id": "P31947-1", "name": "14-3-3 protein sigma", "aln": "---MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAG--DAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQEPQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .*:*:*:****:***:*** ** ..* . ** *:*************.:*::***:******: : .* : ***::* **. :* ** **:..** . . **:**********:***:*** *: : :. :. :*.:* :*** .* **:*********:***:*** * *: * *** :**:*:*:*.**.*:********************:: .:: ", "identical_positions": 132, "similar_positions": 60, "identity": "52.17%" }, { "cls_id": "homologset.agr.FB:FBgn0004908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0J4-1", "uniprot_id": "ARL2_MOUSE", "id": "Q9D0J4-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGED---VDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG---ATLLIFANKQDLPGALS-----CNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08697-1", "uniprot_id": "ARL2_RAT", "id": "O08697-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGLLTILKKMKQKERDVRLLMLGLDNAGKTTILKKFNGED---VDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG---ATLLIFANKQDLPGALS-----CNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36404-1", "uniprot_id": "ARL2_HUMAN", "id": "P36404-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGED---IDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG---ATLLIFANKQDLPGALS-----SNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFTAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06849-1", "uniprot_id": "ARL2_DROME", "id": "Q06849-1", "name": "ADP-ribosylation factor-like protein 2", "aln": "MGFLTVLKKMRQKEREMRILLLGLDNAGKTTILKRFNGEP---IDTISPTLGFNIKTLEHNGYTLNMWDVGGQKSLRSYWRNYFESTDGLVWVVDSADRMRLESCGQELQVLLQEERLAG---ATLLVLCNKQDLPGALS-----SNEIKEILHLEDITTHHWLVAGVSAVTGEKLLSSMDWLIADIAKRIFTLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39110-1", "uniprot_id": "CIN4_YEAST", "id": "P39110-1", "name": "GTP-binding protein CIN4", "aln": "MGLLSIIRKQKLRDKEIRCLILGLDNSGKSTIVNKLLPKDEQNNDGIMPTVGFQIHSLMIKDVTISLWDIGGQRTLRPFWDNYFDKTQAMIWCIDVSLSMRFDETLQELKELINRDENRIGYECAVIVVLNKIDLVEDKSELHRRCLLVESELKCLFKPDIRIELVKCSGVTGEGIDNLRDRLVESCHFTQ----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*::::* : :::::* *:*****:**:**:::: : * * **:**:*::* .. .:.:**:***::**.:* ***:.*:.::* :* : *::. :**: *: .:. .::::. ** ** * . :.. *. : : *.**** : * *: . ", "identical_positions": 54, "similar_positions": 68, "identity": "27.69%" }, { "cls_id": "homologset.agr.FB:FBgn0004913", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFT1-1", "uniprot_id": "D3ZFT1_RAT", "id": "D3ZFT1-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVISSGKKPVNETVKKNEKTKPSEGTVKGKKGVKEAKVNNPCKEDASRPKQHNKKKRIIYDSDSESEETVQVKNAKKKSEKLPVSCKPGKISRKDPVTYISETDEDDDFLCKKAASKSKENGVSTNSYLGASNVKKNEENTKTKSKPLSPIKLTPTSVLDYFGTESVQRSGKKMVASKKKESSQTPDDSRLNDEAIAKQLQLDEDAELERQLHEDEEFARTLALLDEEPKTKKARKDSEEGE-SFSPAKAELSKAAKQKSPA--NAEHFSIGRKTYSPAKYGKGRGSEGTKQPCRS-AHQKEACSSLKASSKLALMKAQEENSYKETELLAAKR-ESAIEPKGEKTTPRKTKGSPTKRESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLTFVITGVLESIEREEAKSLIERYGGKVTGNVSKKTSYLVMGRDSGQSKSDKAAALGTKILDEDGLLDLIRTMPG---------KKSKYEIAAEAEMKKEKSKLERTPQKNDQGKRKLSPTKRELEPKKSKLTPLKHSPRKAVKEEERVCPRGLDAKEPHGSHSA--------------SREECLLWVDKYKPTSLKNIIGQQGDQSCANKLLRWLRNWHKSSPEEKKHAAKFGKVASKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKNSLKAIVAESLNNTSIKGFYTSGASPS--VSARHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKSAMLSIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQSKVLTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMS----LMDKSDLFFHDYSIAPLFVQENYLHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDNQIRS-KQNWSLLPTQAIYASVVPGELMRGYMSQFPSFPSWLGKHSSTGKHDRTVQDLSLHMSLRTYSSKRTVNMDYLSHIRDALVRPLTSQGVEGVQRVVTLMDTYYLVKEDFDNIMEVSSWGGKP-STFSKLDPKVKAAFTRAYNKEAHLTPYSLQVVKASRPSIGPALDSEYNEESQEDA-------TQSDEKEQDALETDAMIKKKTRSSKPSKSEKEKESKKGKGKNSKK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35601-1", "uniprot_id": "RFC1_MOUSE", "id": "P35601-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVISSGKKPVNETVK-NEKTKASEGTVKGKKGVKEAKVNNSGKEDASKPKQHSKKKRIIYDSDSESEETVQVKNAKKKSEKLSLSYKPGKVSQKDPVTYVSETDEDDDFVCKKAASKSKENGVSTNSYLGTSNVKKNEENVKTKNKPLSPIKLTPTSVLDYFGTESVQRSGKKMVTSKRKESSQNTEDSRLNDEAIAKQLQLDEDAELERQLHEDEEFARTLALLDEEPKIKKARKDSEEGEESFSSVQDDLSKAEKQKSPN--KAELFSTARKTYSPAKHGKGRASEDAKQPCKS-AHRKEACSSPKASAKLALMKAKEESSYNETELLAARRKESATEPKGEKTTPKKTKVSPTKRESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLTFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKILDEDGLLDLIRTMPG---------KRSKYEMAAEAEMKKEKSKLERTPQKNDQGKRKISPAKKESESKKCKLTLLKNSPMKAVKKEASTCPRGLDVKETHGNRSS--------------NKEECLLWVDKYKPASLKNIIGQQGDQSCANKLLRWLRNWHKSSPEEKKHAAKFGKLASKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKNSLKAVVAESLNNTSIKGFYTSGAAPS--VSARHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKSAMLSIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQSKALTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMS----LMDKSDLFFHDYSIAPLFVQENYLHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDNQIRS-KQNWSLLPTQAIYASVLPGELMRGYMTQFPSFPSWLGKHSSTGKHDRIVQDLSLHMSLRTYSSKRTVNMDYLSHIRDALVRPLTSQGVEGAQHVIKLMDTYYLMKEDFENIMEVSSWGGKP-SAFSKLDPKVKAAFTRAYNKEAHLTPYSLQVVKTSRLSTGPALDSEYSEEFQEDD-------TQS-EKEQDAVETDAMIKKKTRSSKPSKSEREKESKKGKGKNWKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35251-1", "uniprot_id": "RFC1_HUMAN", "id": "P35251-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKKARKDTEAGE-TFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSSPAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMPG---------KKSKYEIAVETEMKKE-SKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASS--VSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAKKDIKMGPFDVARKVFAAGEETAHMS----LVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDSQIRS-KQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDVVALMDTYYLMKEDFENIMEISSWGGKP-SPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIKASRHSTSPSLDSEYNEELNEDD-------SQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKGKGKSSKK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35600-1", "uniprot_id": "RFC1_DROME", "id": "P35600-1", "name": "Replication factor C subunit 1", "aln": "MQRGIDSFFKRLP-------------AKAKSAEAE-----------------NGETPSKAPKRRKAVIISSDE--DEVVSPPETKKRKASKTAS------SEDDVVAATPEP------IAKKARNGQKP---------ALSKLKR---------------HVDPT---ELFG-----GETKRVIVPKPK-----------------------TKAVLE---FENEDIDRSLMEVDLDESIKEAAPEK----------------------------KVHSITRSSPSP--------------------------------------KRAKNSSPEPPKPKSTKSKATTPRVKKEKPAADLESSVLTDEE-----RHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMEREEAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLIREKSGIAKQVKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKH-DIAKHKVKEEHTSPKETKDKLNDVPAVTLKVKKEPSSQKEHPPSPR--TADLKTLDVVGMAWVDKHKPTSIKEIVGQAGAASNVTKLMNWLSKWYVN-HDGNKKPQRPNPWAKNDDGSFYKAALLSGPPGIGKTTTATLVVKELGFDAVEFNASDTRSKRLLKDEVSTLLSNKSLSGYFT-GQGQA--VSRKHVLIMDEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQIKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHIALLSAKEDAS----QKSGQQVATKDLKLGPWEVVRKVFTA-DEHKHMS----FADKSDLFFHDYSLAPLFVQQNYLQVLPQ---GNKKDVLAKVAATADALSLGDLVEKRIRA-NSAWSLLPTQAFFSSVLPGEHMCGHFTGQINFPGWLGKNSKSGKRARLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPLAKDGQEGVPAALDVMKDYHLLREDLDSLVELTSWPGKK-SPLDAVDGRVKAALTRSYNKEVMAYSYSAQAGIKKKKSEAAGADDDYLDEGPGEEDGAGGHLSSEEDEDKDNLELDSLIKAKKRTTTSKASGGSKKATSSTASKSKAKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38630-1", "uniprot_id": "RFC1_YEAST", "id": "P38630-1", "name": "Replication factor C subunit 1", "aln": "-MVNISDFFGKNK----------------KSVRS------------------STSRPTRQVGSSKPEVIDLDTESDQESTNKTPKKMP-------------------------------------------------------------------------------------------------------------------------------------------VSNVIDVSETPEGEKK--------------------------------LPLPAKRKASSP---------------------------------------TVKPASSKKTKP-SSKSSDSASNITAQDVLDKIPSLDLSNVHVKENAKFDFKSANSNADPDEIVSEIG------SFPEGKPNCLLGLTIVFTGVLPTLERGASEALAKRYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAE---------GGDGEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSGGHLERDNVVREEDK----------------------------------------LWTVKYAPTNLQQVCGNKGS---VMKLKNWLANWENSKKNSFKHAGK-------DGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEAQNLNGKHFVIIMDEVDGMSGG-DRGGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEISKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLSTRPSVLKPGQS-HLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRTGSTIGGGGVGTSTSTPDFEDVVDADDNPVPADDEETQDSSTDLKKDKLIKQKAKPTKRKTATSKPGGSKKRKTKA------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .** *. . . : * : . * :: .** .: :. . :: . *.: ** : * : : ::: .: . . : . :. . : * :. . . .:*:* :** ** :*.**** ::** :::: :.**.:* :..* . :*:* ::* .* * :.*:*: :** .. . * : : . * * . : : : : . :: : . . .: *. *: *:.:: : *: * . ** .** :* . : *:. : *... ::**:* ****:****:* ** :***:. :* ****.*** *: * *.* *: *::. . . :..:********:*. ****: :* : :.:. *:* :**:** **:*.: . * *::*:** :.**. :::*.::* .*: * ::.:* :. *:** :: :: .: .. : .: *:: : *:::.:*:: . * : ** *:*.*:.::**::*:**: . * . . * :: :*:.:. **:*:.:**: :. ***** :*. :** *.. : *::: .*..***::*.:.* * *:: * : * .: :.:** . : . :: *: .:* :. .: :*. *:* :** :.::*. . : :. : **:.:** **. . . . ... . :: .. :... :: * :** * :.:. . . . . .. ", "identical_positions": 185, "similar_positions": 301, "identity": "15.68%" }, { "cls_id": "homologset.agr.FB:FBgn0004914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M342-1", "uniprot_id": "F1M342_RAT", "id": "F1M342-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------MNTTDS-GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKE-----AVQNERDRISTRRSTYEGT---NIPSINTLAQAEVRSCQISV---PNPSASTDINVKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCEV------EVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPGKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAAND------GGHPHHPMHPHLSQDPLTGQTILLGPMSTLVHTD-----------------------------QIATPETPLPSPPQGSGQEQYKIT-------ANQASV--ISHQPLSKQKQL--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUU6-1", "uniprot_id": "HNF4G_MOUSE", "id": "Q9WUU6-1", "name": "Hepatocyte nuclear factor 4-gamma", "aln": "---------------------------------------------------------------------------------------------------------------------------------MNTTDS-GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKE-----AVQNERDRISTRRSTYEGS---NIPSINTLAQAEVRSCQISV---PSPSSSTDINIKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCEV------EVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAAND------GSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHTD-----------------------------QIATPETPLPSPPQGSGQEPYKIT-------ANQASV--ISHQSLSKQKQL--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14541-1", "uniprot_id": "HNF4G_HUMAN", "id": "Q14541-1", "name": "Hepatocyte nuclear factor 4-gamma", "aln": "---------------------------------------------------------------------------------------------------------------------------------MNTTDN-GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKE-----AVQNERDRISTRRSTFDGS---NIPSINTLAQAEVRSRQISV---SSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEV------EISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASND------GSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHAD-----------------------------QISTPETPLPSPPQGSGQEQYKIA-------ANQASV--ISHQHLSKQKQL--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22449-1", "uniprot_id": "HNF4A_RAT", "id": "P22449-1", "name": "Hepatocyte nuclear factor 4-alpha", "aln": "-----------------------------------------------------------MRLSKTLADMDMADYS-----------------------AALDPAYTTLEFENVQVLTMGNDTSPSEGANLNSSNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE-----AVQNERDRISTRRSSYEDS---SLPSINALLQAEVLSQQITS---PISGINGDIRAKKIANITDVCESMKEQLLVLVEWAKYIPAFCELLLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELA-----EMSRVSIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSASD------APHAHHPLHPHLMQEHMGTNVIVANTMPSHLSNGQ-------------------MCEWPRPRGQAATPETPQPSPPSGSGSESYKLLPGAITTIVKPPSA--IPQPTITKQEAI--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49698-1", "uniprot_id": "HNF4A_MOUSE", "id": "P49698-1", "name": "Hepatocyte nuclear factor 4-alpha", "aln": "-----------------------------------------------------------MRLSKTLAGMDMADYS-----------------------AALDPAYTTLEFENVQVLTMGNDTSPSEGANLNSSNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE-----AVQNERDRISTRRSSYEDS---SLPSINALLQAEVLSQQITS---PISGINGDIRAKKIANITDVCESMKEQLLVLVEWAKYIPAFCELLLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELA-----EMSRVSIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSASD------APHTHHPLHPHLMQEHMGTNVIVANTMPSHLSNGQ-------------------MCEWPRPRGQAATPETPQPSPPSGSGSESYKLLPGAITTIVKPPSA--IPQPTITKQEAI--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41235-1", "uniprot_id": "HNF4A_HUMAN", "id": "P41235-1", "name": "Hepatocyte nuclear factor 4-alpha", "aln": "-----------------------------------------------------------MRLSKTLVDMDMADYS-----------------------AALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE-----AVQNERDRISTRRSSYEDS---SLPSINALLQAEVLSRQITS---PVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELA-----EMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSD------APHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQ-------------------MCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSA--IPQPTITKQEVI--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PEX6-1", "uniprot_id": "A0A8M9PEX6_DANRE", "id": "A0A8M9PEX6-1", "name": "", "aln": "-----------------------------------------------------------MRLSKPLVDMEMADYS-----------------------EALDPAYTTLEFENMQVLAMSTDSSPQESANMNAANHLGAGTLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFNRQCIVDKDKRNQCRYCRLKKCFRAGMKKEVISSSAVQNERDRISTRRSSYEDS---SLPSINALIQADVLSRQISS---PGPILNGDIRTKKVAAIMDVCESMKQQLLVLVEWAKYIPAFCDLPLDDQVALLRAHAGEHLLLGAAKRSMMYKDILLLGNDHIIPRNCPEL------EVSRVAVRILDELVLPFQDLQIDDNEYACLKAIVFFDPDAKGLSDPSKIKRMRYQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANE------APHAHHSLHPHLVQEHLSNNVIVTANMATPLHNG-----------------------------QMSTPETPIPSPPTASGSDHYKMASGVIATVPKQPSS--IPQPTITKQEAI--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49866-1", "uniprot_id": "HNF4_DROME", "id": "P49866-1", "name": "Transcription factor HNF-4 homolog", "aln": "MMKHPQDLSVTDDQQLMKVNKVEKMEQELHDPESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKE-----AVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNPLPLSPPNQSNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANSADDSFRAYAASTAAAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQESSYLDMPVKHYNGSRSGPLPTQHSPQRMHPYQRAVASPVEVSSGGGGLGLRNPADITLNEYNRSEGSSAEELLRRTPLKIRAPEMLTAPAGYGTEPCRMTLKQEPETGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :****************************:**.* *:*** *:*:**************:***:****** ********** **:: :.. . *: :* :*: * * . . . *: *:.* * *******:***.****** **** :* ******************* ::*** **:***.*. :: *:. : ::**:. *::**** :::: ***.*:* :**::****:****.:* :** :* *: .*****.****:*******:**:**.************** *:**:.:**.********* : : : :. : : : : . ::. :. .:. .*.. .: : . : ::*: ", "identical_positions": 208, "similar_positions": 101, "identity": "29.34%" }, { "cls_id": "homologset.agr.FB:FBgn0004915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62916-1", "uniprot_id": "TF2B_RAT", "id": "P62916-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDALPRVTCPNHPDAI--LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND-KATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETS------------VDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPSDFKFD--TPVDKLPQL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62915-1", "uniprot_id": "TF2B_MOUSE", "id": "P62915-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDALPRVTCPNHPDAI--LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND-KATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETS------------VDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPSDFKFD--TPVDKLPQL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00403-1", "uniprot_id": "TF2B_HUMAN", "id": "Q00403-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDALPRVTCPNHPDAI--LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND-KATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETS------------VDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPTDFKFD--TPVDKLPQL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29052-1", "uniprot_id": "TF2B_DROME", "id": "P29052-1", "name": "Transcription initiation factor IIB", "aln": "---------MASTSRLDNN-KVCCYAHPESP--LIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNE-KSGVDPSRVGGPENPLLSGGDLSTIIGPGTGSASFDAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLFKQVHDGKNLKGRSNDAKASACLYIACRQEGVPRTFKEICAVSKISKKEIGRCFKLTLKALETS------------VDLITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDIVPGRSPISVAAAAIYMASQASEHKRSQKEIGDIAGVADVTIRQSYKLMYPHAAKLFPEDFKFT--TPIDQLPQM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29055-1", "uniprot_id": "TF2B_YEAST", "id": "P29055-1", "name": "Transcription initiation factor IIB", "aln": "MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : * ::* : **::*. ****:.*:::*. ********: : ****** ..****...:*** ** * : * *.:..*...*. : ** :*: :.* :**: : * ::: :* :: *.***:: :: :*.: *.**: *.****** :: ::..**:*: ::: : *. . :. . :: ***::* ** * :* : *:*. *:. :.*:***::*..:**: : ::*: *:: **:..*:::* : .*. :: ..:*:** : ", "identical_positions": 95, "similar_positions": 115, "identity": "27.54%" }, { "cls_id": "homologset.agr.FB:FBgn0004919", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZI66-1", "uniprot_id": "D3ZI66_RAT", "id": "D3ZI66-1", "name": "", "aln": "--------------------------MAARRRPAAGVGAR--DALAVLALALCAPGVGGG---ALEWYSATVSIEYVD----------PQS--NLTVWSVTESGRFGDSSLREERQGLVGVPRAP---ADAEGCAPDTRFVAP---GALGNAPWVALVARGG-CTFKDKVLAAARRNASAVVVYNQE-RYGNATEPMSHAGTGSIVVIMISYPKGREISDLVQKGIPVKMRIEIGTRHMQ--EFISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQFGSQ-NHRKETKKVIGQLPLHTVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPEDAQDLPIPEAAPGSVSVGNLSVTVQDEERSE-SNLPSSSSSEFGP-HRPCLKEDAEEDTALLGAGR-------------------SDPQHGGSIC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2C5-1", "uniprot_id": "RN149_MOUSE", "id": "Q3U2C5-1", "name": "E3 ubiquitin-protein ligase RNF149", "aln": "--------------------------MAARRRPAAGVGAR--DALAVLALALCTPGVGGG---ALEWYSAMVSIEYVD----------PQS--NLTVWSVSESGRFGESSLREERQGLVGVPRAP---APAEGCAPDTRFVAP---GALGNAPWVALVARGG-CTFKDKVLAAARRNASAVVVYNLE-SNGNATEPMSHAGTGNIVVIMISYPKGREIFDLVQKGIPVKMRIEIGTRHMQ--EFISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQFGSQ-NHRKETKKVIGQLPLHTVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPEDTQELPTPEAAPGRVSVGNLSVTSQDEERSE-SNLPSSSSSESGP-HRPCLKEDAGEDTALLGAGR-------------------SEPQHGGSIC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NC42-1", "uniprot_id": "RN149_HUMAN", "id": "Q8NC42-1", "name": "E3 ubiquitin-protein ligase RNF149", "aln": "--------------------------MAWRRREAS-VGARGVLALALLALALCVPGARGR---ALEWFSAVVNIEYVD----------PQT--NLTVWSVSESGRFGDSSPKEGAHGLVGVPWAPG--GDLEGCAPDTRFFVPEP-GGRGAAPWVALVARGG-CTFKDKVLVAARRNASAVVLYNEE-RYGNITLPMSHAGTGNIVVIMISYPKGREILELVQKGIPVTMTIGVGTRHVQ--EFISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQIGSQ-SHRKETKKVIGQLLLHTVKHGEKGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGEPGDVQEMPAPESPPGRDPAANLSLALPDDDGSDDSSPPSASPAESEPQCDPSFKGDAGENTALLEAGR-------------------SDSRHGGPIS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TEB7-1", "uniprot_id": "RN128_HUMAN", "id": "Q8TEB7-1", "name": "E3 ubiquitin-protein ligase RNF128", "aln": "---------------------MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRG----AEAVWTAYLNVSWRV----------PHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGP---GALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFP-GTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHG---PWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALG---IEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREIKS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D304-1", "uniprot_id": "RN128_MOUSE", "id": "Q9D304-1", "name": "E3 ubiquitin-protein ligase RNF128", "aln": "---------------------MGPPPGIGVYCRGGCGAARLLAWCFLLALSPHAPGSRG----AEAVWTAYLNVSWRV----------PHTGVNRTVWELSEEGVYGQDSPLEPVSGVLVPPDGP---GALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLASERGASGAVIFNFP-GTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHG---PWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGKLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALG---IEVDVEDGSVSLQVPVSNEASNTASPHEEDSRSETASSGYASVQGADEPPLEEHAQSANENLQLVNHEANSVAVDVVPHVDNPTFEEDETPDQEAAVREIKS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Y290-1", "uniprot_id": "GOLI_RAT", "id": "Q6Y290-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "-------------------------MSGAARAGPARLAALALLTCSLWP-----TRADN---ASQEYYTALINVTVQE------------PGRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVP-----PNIKQWIALLQRGN-CTFKEKISRAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPP--KNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLAN-DSSLGLEP-LRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEM1-1", "uniprot_id": "GOLI_MOUSE", "id": "Q8VEM1-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "-------------------------MSGAARAGPARLAALALLTCSLWP-----TRADN---ASQEYYTALINVTVQE------------PGRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVP-----PNIKQWIALLQRGN-CTFKEKISRAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPP--KNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRAALGDLAG-DSSLGLEP-LRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XS8-1", "uniprot_id": "GOLI_HUMAN", "id": "Q86XS8-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "-------------------------MSCAGRAGPARLAALALLTCSLWP-----ARADN---ASQEYYTALINVTVQE------------PGRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLPLHGVADHLGCDPQTRFFVP-----PNIKQWIALLQRGN-CTFKEKISRAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPP--KNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLAG-DNSLGLEP-LRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N5S3-1", "uniprot_id": "A0A8M1N5S3_DANRE", "id": "A0A8M1N5S3-1", "name": "E3 ubiquitin-protein ligase RNF130", "aln": "------------------------MLKRLAAPASCSSCLLALLLAFVSPRCSLSIGADKTMVNKEDYYSAIVNATVLD------------HKGNPQQMVTKNDGRYGQNSPKTEAKGIVVAPAAVNGAVDLQGCCPHTRFIVP-----PKTTHWVAIMQRGK-CTFKEKILKAAAFNASAVIIYNNN--TKEDTVTMAHEGTGDIVAVMITESFGKEILGFLEKNQTVLVSVIVGSRGMP--KNINRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISKLTTRTVKRGDKETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHCTCPMCKLNILKALGVMPNLPCVDNMAFDMDRMSRSQTSSQRTALVDLSS-ETSISLEP-LRHSSSSQLPSDEELIPRSGEINIAVTTGHFFNRNSVSPRSVVCEMELPDIQASLDMYDDNKS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZV56-1", "uniprot_id": "D3ZV56_RAT", "id": "D3ZV56-1", "name": "RING finger protein 150", "aln": "-----------------------MTMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEK-----EEWYTAFVNITYTE--PESGAAVAGGGGGAELHTEKSECGRYGEHSPKQDARGEVVMASSVH---DRLACDPNTKFAAP-----AHGKHWIALIPKGN-CTYRDKIRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKELVSLLERNVTVTMYITIGTRNLQ--KYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPSDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPAPQEGEAIFTTNSDQEPAVSSDSDISLIMALEVGLSDVELSTDQDCEEVKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTZ6-1", "uniprot_id": "RN150_MOUSE", "id": "Q5DTZ6-1", "name": "RING finger protein 150", "aln": "-----------------------MTMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEK-----EEWYTAFVNITYLE--PEPGAAVAGSGGGAELHTEKSECGRYGEHSPKQDARGEVVMASSAQ---DRLACDPNTKFAAP-----AHGKHWIALIPKGN-CTYRDKIRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITIGTRNLQ--KYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPAPQEGEAIFTTNSGQEPALSSDSDISLIMALEVGLSDVELSTDQDCEEVKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULK6-1", "uniprot_id": "RN150_HUMAN", "id": "Q9ULK6-1", "name": "RING finger protein 150", "aln": "-----------------------MAMSLIQACCSLALSTWLLSFCFVHLLCLDFTVAEK-----EEWYTAFVNITYAEPAPDPGAGAAG-GGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAH---DRLACDPNTKFAAP-----TRGKNWIALIPKGN-CTYRDKIRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITIGTRNLQ--KYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSDSDISLIMAMEVGLSDVELSTDQDCEEVKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566M8-1", "uniprot_id": "RN150_DANRE", "id": "Q566M8-1", "name": "RING finger protein 150", "aln": "-----------------------MALSVIQACRSLALSTWLLSFCFVHLLCLDFTVAEK-----EEWYTAFVNITYVD--PDT----------AEVRTEKTECGRYGEHSLKREARGVLAMPAAPH---DRHACDPSGRFTPR-----AHG-AWIALISRGN-CTYKDKIRHAVGHNASAVVIFNVGSSNPNETITMPHQGISDVVAIMIPEPKGRELVLLMERNITVHMHITIGTRNLQ--KYVSRTSVVFVSISFIILMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISQLQVRTIRKGDQETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKCCVDPWLVDHRTCPMCKMNILKALGLTSSAECLNELPLDYELAVGGVALNAMVMSDDVMAGDVGGARDPGVRMGGLPQVLLDSEPLSQ--DTMPTEQSELQPIASGSSDVSLTTG--AGHSDIDTPTD----DPKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06003-1", "uniprot_id": "GOLI_DROME", "id": "Q06003-1", "name": "E3 ubiquitin-protein ligase goliath", "aln": "MYIRKTLLLACLVLLFGGLPPLTFPATTTTLVAAMSIANQDLERYFRPGNGTHSFSGMEDRIAVDVYNYAFLNWSYVEH-----------GNMLCNMEFAQEQARYGEGKVLN-VTGRLIHITATDNFSDDYACTPYIRGTLG-APIPDKGETWIALVRRGR-CTFEEKVKHVYQQNAAGVIIYNDK-QVMQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSD-EKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVG-AREMLFPCRIPERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQVIK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : . :* . * : .* * . *:*:: :* **: :*: . .* ..:::* : : .: .:: * .: :::. * : : * : .. *:.**:::*: : : :::** ::: :: .. :**.* :: :* : .: * : **:*** :: .* :*:*.*.* **: *:**** :* ****** :::* * . . : . ", "identical_positions": 53, "similar_positions": 86, "identity": "11.06%" }, { "cls_id": "homologset.agr.FB:FBgn0004921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63218-1", "uniprot_id": "GBG5_HUMAN", "id": "P63218-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GSSSVAAMKKVVQQLRLEAGLNRVKV-----------------------------------SQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKV-CSFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80SZ7-1", "uniprot_id": "GBG5_MOUSE", "id": "Q80SZ7-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GSSSVAAMKKVVQQLRLEAGLNRVKV-----------------------------------SQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKV-CSFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63219-1", "uniprot_id": "GBG5_RAT", "id": "P63219-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GSSSVAAMKKVVQQLRLEAGLNRVKV-----------------------------------SQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKV-CSFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A804HLA8-1", "uniprot_id": "GBG5B_HUMAN", "id": "A0A804HLA8-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GFSSVAATKKVVQQLQLEAGLNSVKV-----------------------------------SQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKV-CSFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3B2WD42-1", "uniprot_id": "A0A3B2WD42_MOUSE", "id": "A0A3B2WD42-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------ML----GSSSVAAMKKVVQQLRLEAGLNRVKV-----------------------------------SLAAAGLKQFCLQNAQHDPLLTGGSSS-TNPFRPQKV-CSFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8L2QRU2-1", "uniprot_id": "A0A8L2QRU2_RAT", "id": "A0A8L2QRU2-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GSFSITAMKKVVQQLRLEARFNRVKV-----------------------------------SQAAADLKQFCLQNAQHYSLLTGVSSS-SNPFRAQKV-CSFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "R4GE45-1", "uniprot_id": "R4GE45_DANRE", "id": "R4GE45-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSNNNASSSSVAAAQKAVKQLRHEADMDRMKV-----------------------------------SQAAKDLINFCVQNAIKDPLLATISPK-DNPFRPPKS-CGLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50151-1", "uniprot_id": "GBG10_HUMAN", "id": "P50151-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----SGASASALQRLVEQLKLEAGVERIKV-----------------------------------SQAAAELQQYCMQNACKDALLVGVPAG-SNPFREPRS-CALL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CXP8-1", "uniprot_id": "GBG10_MOUSE", "id": "Q9CXP8-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----SGASVSALQRLVEQLKLEAGVERIKV-----------------------------------SQAAAELQQYCIQNACKDALLLGVPAG-SNPFREPRS-CALL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLD4-1", "uniprot_id": "A0A8I6GLD4_RAT", "id": "A0A8I6GLD4-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----SEASVSALQCLVEQLKLEACVEGIKV-----------------------------------SQAAAELQQYCIQNACNDALLFGVPAG-SNPFLEPRS-CPLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GAY3-1", "uniprot_id": "A0A8I6GAY3_RAT", "id": "A0A8I6GAY3-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-------------------PVPAAPQRAAPTQLQARVSSPPTAAVGRGDSVRGPWSEAEGVEETAPPTGPSAPPTREGRSRSGVGRRGRAVPGARRAGLPGGSGSGGEDGGGGDGREFTLPFKTWRHWPTQSLADFRKEESSKMSSKTASTNSTAQARRTVQQLRLEASIERIKV-----------------------------------SKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKT-CIIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAS9-1", "uniprot_id": "GBG12_MOUSE", "id": "Q9DAS9-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSKTASTNSIAQARRTVQQLRLEASIERIKV-----------------------------------SKASADLMSYCEEHARSDPLLMGIPTS-ENPFKDKKT-CIIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBI6-1", "uniprot_id": "GBG12_HUMAN", "id": "Q9UBI6-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSKTASTNNIAQARRTVQQLRLEASIERIKV-----------------------------------SKASADLMSYCEEHARSDPLLIGIPTS-ENPFKDKKT-CIIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43425-1", "uniprot_id": "GBG7_RAT", "id": "P43425-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GTNNVAQARKLVEQLRIEAGIERIKV-----------------------------------SKASSELMSYCEQHARNDPLLVGVPAS-ENPFKDKKP-CIIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61016-1", "uniprot_id": "GBG7_MOUSE", "id": "Q61016-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----GTNNVAQARKLVEQLRIEAGIERIKV-----------------------------------SKASSDLMGYCEQHARNDPLLVGVPAS-ENPFKDKKP-CIIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60262-1", "uniprot_id": "GBG7_HUMAN", "id": "O60262-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MS----ATNNIAQARKLVEQLRIEAGIERIKV-----------------------------------SKAASDLMSYCEQHARNDPLLVGVPAS-ENPFKDKKP-CIIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PPG7-1", "uniprot_id": "GBG14_HUMAN", "id": "A0A1W2PPG7-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSKVAINSDIGQALWAVEQLQMEAGIDQVKVRVGASAGGGKRWEHMGQGTGACLGLVWLNQLVCRCPKMAADLLKFCTEQAKNDPFLVGIPAA-TNSFKEKKP-YAIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVY9-1", "uniprot_id": "D3ZVY9_RAT", "id": "D3ZVY9-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MASKVAIGSDIGQARRAVEQLRMEAGITRIKV-----------------------------------SKAATDLLQFCTEQAKSDPFLVGIPAA-TNPFKEKKP-CAIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59768-1", "uniprot_id": "GBG2_HUMAN", "id": "P59768-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MASNN--TASIAQARKLVEQLKMEANIDRIKV-----------------------------------SKAAADLMAYCEAHAKEDPLLTPVPAS-ENPFREKKFFCAIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63213-1", "uniprot_id": "GBG2_MOUSE", "id": "P63213-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MASNN--TASIAQARKLVEQLKMEANIDRIKV-----------------------------------SKAAADLMAYCEAHAKEDPLLTPVPAS-ENPFREKKFFCAIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AF64-1", "uniprot_id": "A0A8I6AF64_RAT", "id": "A0A8I6AF64-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "GAVSVAQRQGLGVTALHPVGPLRRPGAPLAGGFAVAWAPRCFPLSPQTRRSSVARDPASGDTGRAFTEPGARDAAWPGRPRRAPRRGPSPRLSGTGCAPAAGAPQQDPESASLLTAKFCCCSVPCLDLSLYHLSAGSAGMKEGMSNNS--TTSISQARKAVEQLKMEACMDRVKV-----------------------------------SQAASDLLAYCEAHVREDPLIIPVPAS-ENPFREKKFFCTIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50153-1", "uniprot_id": "GBG4_MOUSE", "id": "P50153-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKEGMSNNS--TTSISQARKAVEQLKMEACMDRVKV-----------------------------------SQAASDLLAYCEAHVREDPLIIPVPAS-ENPFREKKFFCTIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50150-1", "uniprot_id": "GBG4_HUMAN", "id": "P50150-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKEGMSNNS--TTSISQARKAVEQLKMEACMDRVKV-----------------------------------SQAAADLLAYCEAHVREDPLIIPVPAS-ENPFREKKFFCTIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63215-1", "uniprot_id": "GBG3_HUMAN", "id": "P63215-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKGETPVNS--TMSIGQARKMVEQLKIEASLCRIKV-----------------------------------SKAAADLMTYCDAHACEDPLITPVPTS-ENPFREKKFFCALL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V8K2-1", "uniprot_id": "G3V8K2_RAT", "id": "G3V8K2-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKGETPVNS--TMSIGQARKMVEQLKIEASLCRIKV-----------------------------------SKAAADLMTYCDAHACEDPLITPVPTS-ENPFREKKFFCALL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63216-1", "uniprot_id": "GBG3_MOUSE", "id": "P63216-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKGETPVNS--TMSIGQARKMVEQLKIEASLCRIKV-----------------------------------SKAAADLMTYCDAHACEDPLITPVPTS-ENPFREKKFFCALL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63077-1", "uniprot_id": "GBG8_RAT", "id": "P63077-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSNN---MAKIAEARKTVEQLKLEVNIDRMKV-----------------------------------SQAAAELLAFCETHAKDDPLVTPVPAA-ENPFRDKRLFCTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63078-1", "uniprot_id": "GBG8_MOUSE", "id": "P63078-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSNN---MAKIAEARKTVEQLKLEVNIDRMKV-----------------------------------SQAAAELLAFCETHAKDDPLVTPVPAA-ENPFRDKRLFCTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK08-1", "uniprot_id": "GBG8_HUMAN", "id": "Q9UK08-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSNN---MAKIAEARKTVEQLKLEVNIDRMKV-----------------------------------SQAAAELLAFCETHAKDDPLVTPVPAA-ENPFRDKRLFCVLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "id": "P38040-1", "name": "Guanine nucleotide-binding protein subunit gamma-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MD---VMSSSLQQQRVVVEQLRREAAIDRQTI-----------------------------------SESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSS-CTVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P61952-1", "uniprot_id": "GBG11_HUMAN", "id": "P61952-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQV-----------------------------------SKCSEEIKNYIEERSGEDPLVKGIPED-KNPFKEKGS-CVIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61953-1", "uniprot_id": "GBG11_MOUSE", "id": "P61953-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MPALHIEDLPEKEKLKMEVEQLRKEVKLQRQQV-----------------------------------SKCSEEIKNYIEERSGEDPLVKGIPED-KNPFKEKGS-CVIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PBN9-1", "uniprot_id": "Q6PBN9_DANRE", "id": "Q6PBN9-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MPIIDVENMTDLDKAKMEVTQLKTEVKLERAKV-----------------------------------SKCCEEITEYIQGGADEDPLVKGIPEE-KNPFKEKGG-CVIC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * **: *. . : . . : : :: . *.* . ", "identical_positions": 6, "similar_positions": 14, "identity": "2.38%" }, { "cls_id": "homologset.agr.FB:FBgn0004924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IM78-1", "uniprot_id": "TOP1M_RAT", "id": "Q6IM78-1", "name": "DNA topoisomerase I, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLLWLRALCRRFQHVP---------------------RRVPSRQVS---RGSKASRAGWG-ETSKSSVKWKQLEHKGPCFAPAYEPLPDGVRFFYDGKPVRLSLAAEEVATFYGKMLHLECTTKEVFRRNFFSDWQKEMTAEERKL----ITHLDKCDFSEIHRHFMERAEARRTLPREQKQKLKEEAEKLQQEFGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVMWLAAWVENIQNSFKYIILNPSSKPKGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHVRLHTPADGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFMED-KDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASITLQEQLRVLTRAEDSLTCKVLAYNRANRAVAVLCNHQRAIPKTFEESMQTLQKKIET-------------------------------------------------------------------KKAQVAEAQVELQKAETDLRMRGDSKSKSF-----------LQKQQRLLK-LEEQLARLCTKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4U6-1", "uniprot_id": "TOP1M_MOUSE", "id": "Q8R4U6-1", "name": "DNA topoisomerase I, mitochondrial", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLLWLRALCRRFQHVP---------------------CRVPSCQVS---RVAKANRAGWE-ETSKSSVKWRQLEHKGPYFTPAYEPLPDGVHFLYDGKPLKLSLAAEEVATFYGKMLHLECTSKEVFRRNFFSDWRKEMTPEERRL----ITHLDKCDFTEIHKHFLERAEARRTLPREQKQKLKEEAEKLQQEFGYCVLDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVMWLAAWVEHIQNSFKYVILNPSSKPKGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFMED-KDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIET-------------------------------------------------------------------KKAQVAEAQVELQKAETDLRMRGDSKPKSF-----------LQKQRRLLK-LEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969P6-1", "uniprot_id": "TOP1M_HUMAN", "id": "Q969P6-1", "name": "DNA topoisomerase I, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MR----------------------------------------------------------------------------------------------------------------------------------------VVRLLRLRAALTLLGEVP---------------------RRPASRGVPGSRRTQKGSGARWEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREV----IKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMEN-KDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQA-------------------------------------------------------------------KKEQVAEARAELRRARAEHKAQGDGKSRSV-----------LEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04750-1", "uniprot_id": "TOP1_MOUSE", "id": "Q04750-1", "name": "DNA topoisomerase 1", "aln": "------------------------------MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHK---------------------------KDKDKDREKSKHSN------------------------SEHKDS-EKKHKEKEKTKHKDGSSEKHKDKHKDRDKERRKEEKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAPPKEDIKPLKRLRDEDDADYKPK----------------------------------------------------------------------------------------------------------------------------------------KIKTEDIKKEKKRKSEEE-----EDGKLKKPKNKDKDKKVAEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNT----ITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDA-------------------------------------------------------------------KKDQLADARRDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUL0-1", "uniprot_id": "TOP1_RAT", "id": "Q9WUL0-1", "name": "DNA topoisomerase 1", "aln": "------------------------------MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHK---------------------------KDKDKDREKSKHSN------------------------SEHKDS-EKKHKEKEKTKHKDGSSDKHKDKHKDRDKEKRKEEKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAPPKEDIKPLKRPRDEDDADYKPK----------------------------------------------------------------------------------------------------------------------------------------KIKTEDIKKEKKRKLEEE-----EDGKLKKPKNKDKDKKVAEPDNKKKKAKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNT----ITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDA-------------------------------------------------------------------KKDQLADARKDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11387-1", "uniprot_id": "TOP1_HUMAN", "id": "P11387-1", "name": "DNA topoisomerase 1", "aln": "------------------------------MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHK---------------------------KEK--DREKSKHSN------------------------SEHKDS-EKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPK----------------------------------------------------------------------------------------------------------------------------------------KIKTEDTKKEKKRKLEEE-----EDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNI----ITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDA-------------------------------------------------------------------KKEQLADARRDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RL46-1", "uniprot_id": "A0A8M1RL46_DANRE", "id": "A0A8M1RL46-1", "name": "DNA topoisomerase I", "aln": "------------------------------MSGDHPHKHRQVESGSVEYNSHKHKDKHKDRQHGHKEQK---------------------------RDK--ERENSKNGH------------------------SEHKSSSERKHREKEKDRLK--------------HKEKRKEEKFHGS-DGKYR-DKENGFVSPSSIKVEEDTDNHHTVKHE--KPLKRERDEDEYEHKPK----------------------------------------------------------------------------------------------------------------------------------------KVKVENEKKVKKRKQEEEDSDF-EERVEKKPKKKIKEEKK-DTTGGKKKAKNQPEEKWKWWEEERYTDGSKWRFLEHKGPVFPPPYEPLPGHIKFYYDGNAMKLSPAAEEVATFYAKMLEHEYTTNEIFRKNFFKDWRKEMTSEEKSK----ITELKKCDFTQMHEYFKAQSEARKQMSKEEKQKNKEENERILQEYGFCLMDNHRERIGNFRIEPPGLFRGRGDHPKMGKLKRRIRPEDIIINCSKDSVQPKAPPGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVERIRAQYREDWRSKEMRIRQRAVALYFIDKLALRAGNEKDEGETADTVGCCSLRVEHIKLHPQLDGQDYVVEFDFLGKDSIRYYNKIPVEKRVFKNLQLFLEN-KQSEDDLFDRLNTSILNKYLQELMDGLTAKVFRTYNASITLQQQLKELTSPGENIPEKILSYNRANRAVALLCNHQRAPPKTFEKSMQNLQTKIDE-------------------------------------------------------------------KKKQLSAAKKEHKAAKADAKALHDEKSKKA-----------VETKKKAVQRISEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVSWCKKWGVPIEKIYSKTQRDKFAWAIDMADEDFEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BH93-1", "uniprot_id": "A0A8M2BH93_DANRE", "id": "A0A8M2BH93-1", "name": "DNA topoisomerase I", "aln": "------------------------------MENELKDDPCSSEEAFSE-KPKKMKAKAKGKTKSQREGK---------------------------EKTHRKMKASEEEI------------------------METEGSGDRRSHVNVK-------------------EEPKEDPDFVTEKKGKKRKRKAD------------NTDGLLS-SAEAPLPKKKKKKVADGQENAS----------------------------------------------------------------------------------------------------------------------------------------TAKQKKMKEKKEKVKKEE-----GERPVSTKKKKTKEEIEAARALKIKKKEEEEKQRWRWWEEEKYENGIKWKFLEHKGPYFPPAYQPLPDDVKFYYNGEPVKLSLPAEEVALYFAQMLDHEYTTKEVFRNNFFKDWRKEMTLEERQL----IMDLKKCDFGELHAMHKEKVEARKNLSKEEKLVNKEANQKIVDEYGFCVLDHHRERIGNFKIEPPGLFRGRGDHPKQGMLKKRIRPEDVIINCSKESRIPEAPAGHKWKEVRHDKTVTWLASWTENVQGSCKYVMLNANSKLKGEKDWEKYEVARKLKTCVDAIRTQYQEDLKSKQMGTRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLHDALDDQKCVVEFDFLGKDCIRYYNKVPVTKRVFKNLKLFMEN-KQGGDDLFDRLNTASLNKHLSSLMPGLTAKVFRTYNASITLQQQLKELSNMKDNVPEKLLSYNRANRAVAVLCNHQRAPPKSFDQSMANLQAKIDS-------------------------------------------------------------------RKEQLDLAKKELKQAKKEAKGSSDNKLLVV-----------VEKKKKAVQRCEEQLLKMEVQATDREENKQIALSTSKLNYLDPRISVAWCKNMEVPLDKIYNKTLRDKFAWAVDMTELDFVF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30189-1", "uniprot_id": "TOP1_DROME", "id": "P30189-1", "name": "DNA topoisomerase 1", "aln": "MSGDVAAENSIHIQNGGSCEVVQSNGVTTNGHGHHHHHHHSSSSSSSSKHKSSSKDKHRDREREHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGSSNSHRSGSSSSHKDKDGSSSSKHKSSSGHHKRSSKDKERRDKDKDRGSSSSSRHKSSSSSRDKERSSSSHKSSSSSSSSKSKHSSSRHSSSSSSKDQPSYDGVFVKPEPVSQQLMHSGSVDAFQMQQLGSYEAAAAGTNFNGNGNVAGANYKNGYEESIVDIKKEEESFNNLSQASSCDYSMSQFRADEPPFVVKHEQSYAEEDSTMNYNDHDDDADEMNDDEEDVPLAMRKRKQEATDRPDGGMDNDDDDDIPLLARKKVKKEKIKKESKEKSKKRVKEEPSDDYGNVKPKKKKMKKEPEPAVSPGKRQKAKAKVEEEEVWRWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREI----IKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEH-KKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKA-------------------------------------------------------------------KREAIEKCESEYHSRD--------------------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04786-1", "uniprot_id": "TOP1_YEAST", "id": "P04786-1", "name": "DNA topoisomerase 1", "aln": "----------------------------------------MTIADASKVNHELSSDDDDDVPLSQTLKK----------------------------------------------------------------------------------------------------------RKVASMNSASLQDEAEPYDSDEAISKISKKKTKKIKTEPVQSSSLPSPPAKKSATSKPK----------------------------------------------------------------------------------------------------------------------------------------KIKKEDGDVKVKTTKKEE---------------QENEKKKREEEEEEDKKAKEEEEEYKWWEKENEDDTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNPVFQKNFFNDFLQVLKESGGPLNGIEIKEFSRCDFTKMFDYFQLQKEQKKQLTSQEKKQIRLEREKFEEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAPEGHKWGEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSE-DEADTVGCCSLRYEHVTLKPPN-----TVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPN-KGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIESVDENWRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * . ** *:*:* *.* *: :* ::: *:*. : *. :**.* ::. :*. : .: :*..***.*: : : * : :*:* :: . . :: . ::* : : : .:: :* :* ::*::.**: ***.****** *** * :*:*: ..*: :* .::: * .* * :* *:* *:.* **. * * : .. **: * . * **: *:* **:* :: ** * : :* * ** ***:*:** :***:*.**.: : ********** **: *: .* :** ***.**: :.: * * *::** * . *. .:*** * . **::*.. * ************* *:*.** :. .:. *:* ** ***.**:******: .. . ::: . : :*. :. : .. . :. :: ::: : .*::**. ::*.*:*:**:***::: :**. **::**:.** * :* **. . :: *", "identical_positions": 184, "similar_positions": 175, "identity": "17.15%" }, { "cls_id": "homologset.agr.FB:FBgn0004926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L45-1", "uniprot_id": "IF2B_MOUSE", "id": "Q99L45-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MS---GDEMIFDPTMSKKKKKKKKPFMLDEEGDAQTEETQPSETKEVEPEPTEEKDVDADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIE--SDAQEPAEPEDDLDIMLGNKKKKKKNVKFPEEDEILEKDEA-LEDEDSKKDDGISFSSQT--AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEK-RKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDT--RLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20042-1", "uniprot_id": "IF2B_HUMAN", "id": "P20042-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MS---GDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIE--SDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEA-LEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEK-RKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDT--RLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41375-1", "uniprot_id": "IF2B_DROME", "id": "P41375-1", "name": "Eukaryotic translation initiation factor 2 subunit 2", "aln": "MD---AEDG-FDPTLLKKKKKKKTTFDLD------AALGLEDDTKKEDPQ----------DEASAEGGAAAEEDNLDLESFGKKKKKKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEEINLDMDFSMAKKKKKSKKKELDELFADQADD-DKSEDKENDEDNSS------TWFGSDRDYTYDELLKRVFEIILDKNPDMAAGRK-PKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDT--RLFFLQCESCGSRCSVASIKSGFQAVTGKRAAIRAKTT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09064-1", "uniprot_id": "IF2B_YEAST", "id": "P09064-1", "name": "Eukaryotic translation initiation factor 2 subunit beta", "aln": "MSSDLAAELGFDPALKKKKKTKK---------------VIPDDF-----------------DAAVNGKENGSGDDL-FAGLKKKKKKSKSVSADAEAEK--------------EPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKAGLDNVDAESKEGTPSAN----SSIQQEVGLPYSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRRRM-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : ***:: ****.** .: : : : . *:* : . *****.*. * * ** : : :. *****. . : : . .. * :..:. . : .: . .*.***.*.*:*: :**::..... ** : ** :* * *** * *: **.: *** *:**: :*:********:**:::*:***:** **:******** *****:**:* :* *::: **:*: *::* * **:***:****..*** : ", "identical_positions": 111, "similar_positions": 83, "identity": "32.46%" }, { "cls_id": "homologset.agr.FB:FBgn0004957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y6B0-1", "uniprot_id": "A0A8I5Y6B0_RAT", "id": "A0A8I5Y6B0-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "----------------------------------------------------------MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLG------LPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVT-WHKMRGAQMIVAMKAVSLGFDLDRG--EVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT-EEKDHLEWDLTVSRPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLAQILSACILSKRCLP-------DCSHRHRLG----LGVRALNLLFGALAVFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJJ7-1", "uniprot_id": "PORCN_MOUSE", "id": "Q9JJJ7-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "----------------------------------------------------------MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLG------LPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVT-WHKMRGAQMIVAMKAVSLGFDLDRG--EVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT-EEKDHLEWDLTVSRPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLAQILSACILSKRCLP-------DCSHRHRLG----LGVRALNLLFGALAIFHLSYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H237-1", "uniprot_id": "PORCN_HUMAN", "id": "Q9H237-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "----------------------------------------------------------MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLG------LPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVT-WHKMRGAQMIVAMKAVSLGFDLDRG--EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT-EEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACVLSKRCPP-------DCSHQHRLG----LGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1X0-1", "uniprot_id": "A0A8M3B1X0_DANRE", "id": "A0A8M3B1X0-1", "name": "", "aln": "----------------------------------------------------------MGSLSRQAFFQELGSGCLLPTVQQGLEQVWQLLLICLVCRLSWRLG------LPNFLKHLSTVVGGFYTLYLFFELHMVWVVLLSLLCYLILFLCRHSSSRGPFLSITILIYLLLGELHMMDTTT-WHKMRGSQMVVAMKAVSLAFDLDKG--IVDKVPSPVEFMGYIYFVGTVIFGPWISFNSYMDAVESRKLSVSWFMKSVISCVKSQLCLLISNCVAPYLFPYFIPVFGNKLLRNKKRKMRGSIKRWLQAYENSLSFHFSNYFVSFLGETTTTLAGAGFT-EEKDNLKWDMTIAKPLYVEFPRSMVEVVTSWNLPMSRWLNTYVFRKALRYGSFT------AIIMTYTASALLHGLSFHIGAVLLTLGFITYIEHVLRKRLSAILNACVLSKRCPS-------DCKHRHKKE----LWVYLINGTFSMLALLHLTYLGSVFGSSSDDMDSDEDGVASHTIQKWTQLSWTSHWLTFALWVFYRLIL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWV9-1", "uniprot_id": "PORCN_DROME", "id": "Q9VWV9-1", "name": "Protein-serine O-palmitoleoyltransferase porcupine", "aln": "MDYQYFEEESDYIDLDEEEEDDDVVTAGSLDHRFGQPNGEEDYYFGGDDVEEELVVDGHGVLELAGRLLESLQSCVQPSVLQVMQYVAPMLLLCLLCRLLCLLYSQRRRLTSLAPLHLFHFACGLIILQITVGYRLLLLLLLAAVGYLLLQLLRLGRRGAQVLAVLTVGSQFLYELLIWRRRSDWPQLRGIQMVVNMKLISLGFDLTASGQLQARIPGPFAYLGYIYSPATCALGPWVSFGCYMDCLVPRNSWLVSLRRLLPNVVICVLAVTVSNCVAPALSDFFG-----------------DSSHFLVMYWDALSVRSSHYFVGMMAQALLVASDQRLDGATKESDMLGPLISQPWRIEWPRSISSLVRSWNIPMHEWLKRYIYAPCKPTASTSRGRILVVVLSTYLVSSLLHGMDLRIYLVLISLAFLAEGESLLRRQLASLLNACITANLCPGKERCRYSHCPSKRRLNSLSYWLARLTNLAFTALAIFHLAYLGVVLLGDDLEVGEDGD----SFLWHWQQAGYLSHYIGLGTFVLYLFIS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : ..*: *:. * :: : :* :*: *** * . * .. *: * . ::: ::**: : **:* * * . . .*:: : :: *: : : * ::** **:* ** :**.*** . :*.*. ::**:* .* :***:** .*::.: * : : . . . *.: :*.**.* * :* ::* * .::*.: *:***.::.:: . :. : *: . :::* :* ***: .:* ***:** **: *:: . .: : .:: ** .*:****:.::: **::*.*:: * :**::*: :*.**: :: * .* ::: . * * **::**:*** :: . : .: . : :* : .: **:: :. :::* :* ", "identical_positions": 110, "similar_positions": 158, "identity": "20.15%" }, { "cls_id": "homologset.agr.FB:FBgn0004959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTQ9-1", "uniprot_id": "A0A0G2JTQ9_RAT", "id": "A0A0G2JTQ9-1", "name": "unspecific monooxygenase", "aln": "---MLATVGSLLAKIW-----------------------------SAINFWTLLLTLLTFLLLADYLKNRRPNNYPPGPWRLPFVGNLFQFDLNISHLHLRIQQFV---KKYGNLISLDFGN-ISVVVITGLPLIKEALINNEQNFLKRPIVPSRYRV---FKDNGIFFANVH-KWKEQRRFALTMLKNFGLGKKSLEQCIQEE----------AHHLVEVIGEEKGQPFDPHFRINNAVSNIICSITFGERFEYDDSQFQELLKLADEVICSEASMTSVLYNVFPLIFK----------------------------YLPGPHQTVFKNWEKLKSIVANMIDRHRKDWNPDEP-RDFVDAFLTE-----------------MTKYPDKTTTSFNEENLIATTLDLFFAGTETTSTTLRWALLYITLNPEVQEKVHSEIDRVIGHGRLPSTDDQDAMPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRDSFLPFSV---------GKRACPGEKLAKSELFIFFTALMQNFTFKAP-TNEK-LSLKLR-KGLSLYPVSYRICAVPR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51590-1", "uniprot_id": "CP2J3_RAT", "id": "P51590-1", "name": "Cytochrome P450 2J3", "aln": "---MLVTAGSLLGAIW-----------------------------TVLHLRILLLAAVTFLFLADFLKHRRPKNYPPGPWRLPLVGCLFHLDP--KQPHLSLQQFV---KKYGNVLSLDFAN-IPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHL---FNKNGLIFSSGQ-TWKEQRRFALMTLRNFGLGKKSLEQRIQEE----------AYHLVEAIKDEGGLPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQ----------------------------YLPGSHQTLFSNWRKLKLFISDIIKNHRRDWDPDEP-RDFIDAFLKE-----------------MAKYPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRESFLPFSM---------GKRACLGEQLARSELFIFITSLIQKFTFKPP-VNEK-LSLQFR-MSVTISPVSHRLCAIPRL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N004-1", "uniprot_id": "A0A8M1N004_DANRE", "id": "A0A8M1N004-1", "name": "", "aln": "------MFGALVKLDL-----------------------------SSVGL-TLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLR----DPMGFNRLM---AQYGEMSTMYLGK-KPAIVLNTIQVAKEALVQ--EAFAGRPCLPVIDWT---SNGCGIIMATFNNSWKQQRRFALHTLRNFGLGKKSIESRVLEE----------SQYLFAELLKDEGEPVNPHHALQNAVSNIFCSIMFGERFDYDNKRLGYLLKILNENMMLTGSAIGQIFNLAP-FIK----------------------------HFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSP-RDFIDAYLLE-----------------IEKQKSNKDSTFQEENLIGSAIDLFFAGTDSTATSIRWGLLFLIQNPDVQERCHEEIVQVLGYDRLPCMDDCDRLPYTHATVHEIQRFAKTVPFGVFHETIWPTKLHGFDIPQGTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESYIPFSL---------GLRACIGESLVRTELFLFATVLLQRIHFSWP-PDAKPLDMDGI-VGIVRYPQTFSIICCSRDSKK------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35293-1", "uniprot_id": "CP2F2_RAT", "id": "O35293-1", "name": "Cytochrome P450 2F2", "aln": "----------MDGVST-----------------------------AILLLLLAVISLS----LTFTSWGKGQ--LPPGPKPLPILGNLLQLRS--QDLLTSLTKLS---KDYGSVFTVYLGP-RRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNF---TKGNGIAFSDGE-RWKILRRFSVQILRNFGMGKRSIEERILEE----------GSFLLDVLRKTEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHFINDNFQIMSSPWGEMYNIFPSLLD----------------------------WVPGPHRRVFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTK-----------------MVQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDANQSFKKSPAFMPFSA---------GRRLCLGEPLARMELFIYLTSILQNFTLHPL-VEPEDIDLTPLSSGLGNLPRPFQLCMRIR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33267-1", "uniprot_id": "CP2F2_MOUSE", "id": "P33267-1", "name": "Cytochrome P450 2F2", "aln": "----------MDGVST-----------------------------AILLLLLAVISLS----LTFSSRGKGQ--LPPGPKPLPILGNLLQLRS--QDLLTSLTKLS---KEYGSVFTVYLGS-RPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNF---TRGNGIAFSDGE-RWKILRRFSVQILRNFGMGKRSIEERILEE----------GSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLD----------------------------WIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTK-----------------MAQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSFKKSPAFMPFSA---------GRRLCLGEPLARMELFIYFTSILQNFTLQPL-VDPEDIDLTPLSSGLGNLPRPFQLCMHIR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24903-1", "uniprot_id": "CP2F1_HUMAN", "id": "P24903-1", "name": "Cytochrome P450 2F1", "aln": "----------MDSIST-----------------------------AILLLLLALVCLL----LTLSSRDKGK--LPPGPRPLSILGNLLLLCS--QDMLTSLTKLS---KEYGSMYTVHLGP-RRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNF---TKGNGIAFSSGD-RWKVLRQFSIQILRNFGMGKRSIEERILEE----------GSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYDIFPSLLD----------------------------WVPGPHQRIFQNFKCLRDLIAHSVHDHQASLDPRSP-RDFIQCFLTK-----------------MAEEKEDPLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSA---------GRRLCLGESLARMELFLYLTAILQSFSLQPL-GAPEDIDLTPLSSGLGNLPRPFQLCLRPR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K2P4-1", "uniprot_id": "A0A0G2K2P4_RAT", "id": "A0A0G2K2P4-1", "name": "unspecific monooxygenase", "aln": "----------MVTCEA-----------------------------TLLLLLILTLMLMSWGWLAHQARARMQKDLPPGPAPLPLLGNLLQLQS--GHLDRVLMELS---SRWGPVFTVWLGP-RPAVVLSGYAALRDALVLQADAFSGRGSMAVFERF---THGNGIVFSNGP-RWRTLRNFALGALKEFGVGTSTIEERILEE----------TACVLDEFQATMGAPFDPRRLLDNAVSNVICTVVFGKRYNYGDPEFLRLLDLFSDNFRIMSSRWGETYNMFPSFMD----------------------------WIPGPHHRIFKNFQELRLFISEQIQWHRQSRQTGEP-RDFIDCFLEQ-----------------MDKEHQDPESHFQDETLVMTTHNLFFGGTETTSTTLRYGLLIMLKYPEVAAKVQEELDATVGRTRAPSLADRAHLPYTNAVLHEIQRFISVLPLGLPRALIRDVNLRNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDQGEFQNNDAFMPFAP---------GKRMCLGAGLARSEIFLFLTAILQKFSLLPV-GSPADIDLTPQCTGLGNVPPAFQLRLVAR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00176-1", "uniprot_id": "CP2B1_RAT", "id": "P00176-1", "name": "Cytochrome P450 2B1", "aln": "----------MEPT-------------------------------ILLLLALLVGFLL---LLVR-GHPKSRGNFPPGPRPLPLLGNLLQLDR--GGLLNSFMQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPI---FKEYGVIFANGE-RWKALRRFSLATMRDFGMGKRSVEERIQEE----------AQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLK----------------------------YFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAP-RDFIDTYLLR-----------------MEKEKSNHHTEFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFST---------GKRICLGEGIARNELFLFFTTILQNFSVSSH-LAPKDIDLTPKESGIGKIPPTYQICFSAR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04167-1", "uniprot_id": "CP2B2_RAT", "id": "P04167-1", "name": "Cytochrome P450 2B2", "aln": "----------MEPS-------------------------------ILLLLALLVGFLL---LLVR-GHPKSRGNFPPGPRPLPLLGNLLQLDR--GGLLNSFMQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPI---FKEYGVIFANGE-RWKALRRFSLATMRDFGMGKRSVEERIQEE----------AQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLK----------------------------YFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAP-RDFIDTYLLR-----------------MEKEKSNHHTEFHHENLMISLLSLFFAGTETGSTTLRYGFLLMLKYPHVTEKVQKEIDQVIGSHRPPSLDDRTKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDTFNPEHFLDADGTLKKSEAFMPFST---------GKRICLGEGIARNELFLFFTTILQNFSVSSH-LAPKDIDLTPKESGIAKIPPTYQICFSAR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12791-1", "uniprot_id": "CP2BA_MOUSE", "id": "P12791-1", "name": "Cytochrome P450 2B10", "aln": "----------MEPS-------------------------------VLLLLALLVGFLL---LLAR-GHPKSRGNFPPGPRPLPLLGNLLQMDR--GGLLKSLIQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPT---FKEYGVIFANGE-RWKTLRRFSLATMRDFGMGKRSVEERIQEE----------AQCLVEELRKSQGAPLDPTFLFQCITANVICSIVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLK----------------------------YFPGAHRQISKNLQELLDYIGHSVERHKATLDPSVP-RDFIDIYLLR-----------------MEKEKSNQNAEFHHQNLMMSVLSLFFVGTETSSTTLHYGFLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYSDAVIHEIQRFSDLIPIGVPHRVTKDTLFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDQFLDANGALKKSEAFLPFSTGQIFDQKSVGKRICLGESIARSELFLFFTSILQNFSVASH-VAPKDIDLTPKESGIGKIPPTYQICFLAR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q593-1", "uniprot_id": "E9Q593_MOUSE", "id": "E9Q593-1", "name": "Cytochrome P450", "aln": "----------MEPS-------------------------------VLLLLALLTGFLL---LLIR-GQPKAYSRLPPGPRPLPFLGNLLQMDR--GGLLKSFIKLR---DKHGDVFTVHLGP-RPVVMLYGTETIKEALVDHSDAFSGRGAIAVIQPI---VQDYGVIFSSGE-RWKTLRRFSLATMRDFGMGKRSVEERIKEE----------AQCLVEELKKYEGAPLDPTFLFQCITANIICSIVFGERFDYTDHQFLHLLDLFYQTLSLISSFSSQLFELFSAVLK----------------------------YFPGTHRQISKNIQEILNYIGHSVEQHKATLDPSAP-RDFIDTYLLR-----------------MEKEKSNHHTEFHHQNLLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVISAHHVPTLEDRIKMPYTEAVIHEIQRFSDLAPIGLPHTVTKDTVFRGYLLPKNTEVYPILSSALHDPQYFEQPDKFNPEHFLDANGALKKSEAFLPFST---------GKRICLGEGIARNELFLFFTALLQNFSLSSP-VAPEDIDLTPKESGFVKIPPVYRICFLPR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZZ08-1", "uniprot_id": "A0A8I5ZZ08_RAT", "id": "A0A8I5ZZ08-1", "name": "Cytochrome P450", "aln": "----------MEPS-------------------------------VLLLLAVLLSFLL---LLVR-GHAKIHGRLPPGPCPVPLLGNLLQMDR--RGLLKSFIQLRPIWEKYGDVFTVHLGL-RPVVVLCGTQTIREALVDHAEAFSGRGTIAGLEPV---FQDYGIFFSSGE-QWKTLRRFSMATMRDFGMRKKSVEERIKEE----------SQCLVEELKKYQGAPLDPTFLFQCITSNIICSIVFGECFDYTDHQFLHLLDLMYQTFSLLSSIFSQVFELFPGVLK----------------------------YFPGAHRQISRNLHEILDFIGQSVEKHRATLDPNAP-RDFIYTYLLH-----------------MEK-KSNHYTEFHHWNLLSSVLSLFFAGTETSSTTLRYGFLIMLKYPHITEKVQKEIDCVIGSHRLPTLDDRSKMPYTEAVIHEIQRFSDLAPIGTPHRVIKDTIFRGYLLPKNTEVFPILSSVLHDPQYFEQPDIFNLQHFLDANGALKIIEAFLPFST---------GKRICLGESIARNELFLFFTTILQNFSVSSP-VAPKDIDLTPKESGIGRIPQVYQICFLAH----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LT33-1", "uniprot_id": "F1LT33_RAT", "id": "F1LT33-1", "name": "Cytochrome P450", "aln": "----------MELG-------------------------------VFLLLTFTVGFLL---LLASQNRPKTHGHLPPGPRPLPFLGNLLQMNR--RGLLRSFMQLQ---EKYGDVFTVHLGP-RPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPV---VQGYGVIFANGE-RWKILRRFSLVTMRNFGMGKRSVEERIKEE----------AQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLK----------------------------YFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTP-RDFIDTYLLH-----------------MEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFST---------GKRTCLGEGIARNELFIFFTALLQNFSLASP-VAPEDIDLTPINSGAGKIPSPYQINFLSRCVG-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64583-1", "uniprot_id": "CP2BF_RAT", "id": "Q64583-1", "name": "Cytochrome P450 2B15", "aln": "----------MELG-------------------------------VLLLLTFTVGFLL---LLASQNRPKTHGHLPPGPRPLPFLGNLLQMNR--RGLLRSFMQLQ---EKYGDVFTVHLGP-RPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPV---VQGYGVIFANGE-RWKILRRFSLVTMRNFGMGKRSVEERIKEE----------AQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLK----------------------------YFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTP-RDFINTYLLR-----------------MEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFST---------GKRICLGEGIAQNELFIFFTAILQNFSLASP-VAPEDIDLSPINSGISKIPSPYQIHFLSRCVG-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13107-1", "uniprot_id": "CP2B3_RAT", "id": "P13107-1", "name": "Cytochrome P450 2B3", "aln": "----------MDTS-------------------------------VLLLLAVLLSFLL---FLVR-GHAKVHGHLPPGPRPLPLLGNLLQMDR--GGFRKSFIQLQ---EKHGDVFTVYFGP-RPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPI---MQEYGVSFVNEE-RWKILRRLFVATMRDFGIGKQSVEDQIKEE----------AKCLVEELKNHQGVSLDPTFLFQCVTGNIICSIVFGERFDYRDRQFLRLLDLLYRTFSLISSFSSQMFEVYSDFLK----------------------------YFPGVHREIYKNLKEVLDYIDHSVENHRATLDPNAP-RDFIDTFLLH-----------------MEKEKLNHYTEFHHWNLMISVLFLFLAGTESTSNTLCYGFLLMLKYPHVAEKVQKEIDQVIGSQRVPTLDDRSKMPYTEAVIHEIQRFSDVSPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALHDPQYFEQPDTFNPEHFLDANGALKKCEAFMPFSI---------GKRMCLGEGIARSELFLFFTTILQNYSVSSP-VDPNTIDMTPKESGLAKVAPVYKICFVAR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20813-1", "uniprot_id": "CP2B6_HUMAN", "id": "P20813-1", "name": "Cytochrome P450 2B6", "aln": "----------MELS-------------------------------VLLFLALLTGLLL---LLVQ-RHPNTHDRLPPGPRPLPLLGNLLQMDR--RGLLKSFLRFR---EKYGDVFTVHLGP-RPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPF---FRGYGVIFANGN-RWKVLRRFSVTTMRDFGMGKRSVEERIQEE----------AQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLK----------------------------YFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAP-KDLIDTYLLH-----------------MEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSL---------GKRICLGEGIARAELFLFFTTILQNFSMASP-VAPEDIDLTPQECGVGKIPPTYQIRFLPR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10610-1", "uniprot_id": "CP2G1_RAT", "id": "P10610-1", "name": "Cytochrome P450 2G1", "aln": "----------MALGGA-----------------------------FSIFMTLCLSCLL---ILIAWKRTSRGGKLPPGPTPIPFLGNLLQVRI--DATFQSFLKLQ---KKYGSVFTVYFGP-RPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKN---FQGYGLALSNGE-RWKILRRFSLTVLRNFGMGKRSIEERIQEE----------AGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDMYWGVIQ----------------------------YFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNP-RDFIDCFLIK-----------------MYQDKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSS---------GKRICVGEALARMELFLYFTSILQRFSLRSL-VPPADIDIAHKISGFGNIPPTYELCFMAR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15149-1", "uniprot_id": "CP2A2_RAT", "id": "P15149-1", "name": "Cytochrome P450 2A2", "aln": "----------MLDTGL-----------------------------LLVVILASLSVMF---LVSLWQQKIR-ERLPPGPTPLPFIGNYLQLNM--KDVYSSITQLS---ERYGPVFTIHLGP-RRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNIL---FKGYGFSLSNVE-QAKRIRRFTIATLRDFGVGKRDVQECILEE----------AGYLIKTLQGTCGAPIDPSIYLSKTVSNVINSIVFGNRFDYEDKEFLSLLEMIDEMNIFAASATGQLYDMFHSVMK----------------------------YLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSP-RNFIDSFLIR-----------------MQEEK-YVNSEFHMNNLVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPDVEAKVHEEIERVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPIIGSLMTEPKFFPNHKDFNPQHFLDDKGQLKKNAAFLPFSI---------GKRFCLGDSLAKMELFLLLTTILQNFRFKFP-MNLEDINEYPSPIGFTRIIPNYTMSFMPI----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A820-1", "uniprot_id": "D4A820_RAT", "id": "D4A820-1", "name": "Cytochrome P450", "aln": "----------MEAAST-----------------------------WALLLALLLLLLA---LTLP--RTPARGQLPPGPTPLPLLGNLLQLRP--GALYSGFLRLS---KKYGPVFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGRGTLATLDKT---FDGHGVFFANGE-RWKQLRKFTLLALRDLGMGKREGEELIQEE----------VQNLVKAFQRTEGRPFNPSMLLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQ----------------------------PLPGPHTQLQHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQK-----------------MAQEKEDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLKYPQVQKRVREELIQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKHEAFLPYSL---------GKRVCLGEGLARAELWLFFTSILQAFSLDTP-CPPGDLSLKPAVRGLFNIPPDFQLQVWPTGDQSR-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBX6-1", "uniprot_id": "CP2S1_MOUSE", "id": "Q9DBX6-1", "name": "Cytochrome P450 2S1", "aln": "----------MEAAST-----------------------------WALLLALLLLLLL---LSLTLFRTPARGYLPPGPTPLPLLGNLLQLRP--GALYSGLLRLS---KKYGPVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTLATLDKT---FDGHGVFFANGE-RWKQLRKFTLLALRDLGMGKREGEELIQAE----------VQSLVEAFQKTEGRPFNPSMLLAQATSNVVCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQ----------------------------PLPGPHTQLQHHLGTLAAFTIQQVQKHQGRFQTSGPARDVVDAFLLK-----------------MAQEKQDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLRYPQVQQRVREELIQELGPGRAPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLDEDGRLRKHEAFLPYSL---------GKRVCLGEGLARAELWLFFTSILQAFSLETP-CPPGDLSLKPAISGLFNIPPDFQLRVWPTGDQSR-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SQ9-1", "uniprot_id": "CP2S1_HUMAN", "id": "Q96SQ9-1", "name": "Cytochrome P450 2S1", "aln": "----------MEATGT-----------------------------WALLLALALLLL----LTLALSGTRARGHLPPGPTPLPLLGNLLQLRP--GALYSGLMRLS---KKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGT---FDGHGVFFSNGE-RWRQLRKFTMLALRDLGMGKREGEELIQAE----------ARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLR----------------------------PLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLK-----------------MAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSL---------GKRVCLGEGLAKAELFLFFTTILQAFSLESP-CPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33273-1", "uniprot_id": "CP255_RAT", "id": "P33273-1", "name": "Cytochrome P450 2C55", "aln": "----------MD---------------------------------PVLVLVLTLSCLL---LLSLWRQSSGRGKLPPGPTPLPIIGNILQIDV--KDISKSFSYFS---KIYGPVFTLYFGP-KPTVVVHGYEAVKEALDDLGEEFSGRGSFPIVERM---NNGLGLIFSNGT-KWKELRHFSLMTLRNFGMGKRSIEDRIQEE----------ASCLVEELRKTNGSLCDPTFILSCAPSNVICSVVFHNRFDYKDENFLNLMEKLNENFKILNSPWMQVCNALPAFID----------------------------YLPGSHNRVIKNFAEIKSYILRRVKEHQETLDMDNP-RDFIDCFLIK-----------------MEQEKHNPRTEFTIESLMATVSDVFVAGSETTSTTLRYGLLLLLKHTEVTAKVQEEIDHVIGRHRRPCMQDRTRMPYTDAMVHEIQRYINLIPNNVPHAATCNVRFRNYVIPKGTDLVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFST---------GKRMCVGEALARMELFLLLTTIVQNFNLKSF-VDTKDIDTTPMANTFGRVPPSYQLCFIPR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08683-1", "uniprot_id": "CP2CB_RAT", "id": "P08683-1", "name": "Cytochrome P450 2C11", "aln": "----------MD---------------------------------PVLVLVLTLSSLL---LLSLWRQSFGRGKLPPGPTPLPIIGNTLQIYM--KDIGQSIKKFS---KVYGPIFTLYLGM-KPFVVLHGYEAVKEALVDLGEEFSGRGSFPVSERV---NKGLGVIFSNGM-QWKEIRRFSIMTLRTFGMGKRTIEDRIQEE----------AQCLVEELRKSKGAPFDPTFILGCAPCNVICSIIFQNRFDYKDPTFLNLMHRFNENFRLFSSPWLQVCNTFPAIID----------------------------YFPGSHNQVLKNFFYIKNYVLEKVKEHQESLDKDNP-RDFIDCFLNK-----------------MEQEKHNPQSEFTLESLVATVTDMFGAGTETTSTTLRYGLLLLLKHVDVTAKVQEEIERVIGRNRSPCMKDRSQMPYTDAVVHEIQRYIDLVPTNLPHLVTRDIKFRNYFIPKGTNVIVSLSSILHDDKEFPNPEKFDPGHFLDERGNFKKSDYFMPFSA---------GKRICAGEALARTELFLFFTTILQNFNLKSL-VDVKDIDTTPAISGFGHLPPFYEACFIPVQRADSLSSHL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20814-1", "uniprot_id": "CP2CD_RAT", "id": "P20814-1", "name": "Cytochrome P450 2C13, male-specific", "aln": "----------MD---------------------------------PVVVLLLSLFFLL---FLSLWRPSSGRGKLPPGPTPLPIIGNFFQVDM--KDIRQSLTNFS---KTYGPVYTLYVGS-QPTVVLHGYEALKEALVDHGEEFSGRGRLPICEKV---AKGQGIAFSHGN-VWKATRHFTVKTLRNLGMGKGTIEDKVQEE----------AKWLVKELKKTNGSPCDPQFIMGCAPGNVICSIILQNRFDYEDKDFLNLIEKVNEAVKIISSPGIQVFNIFPILLD----------------------------YCPGNHNIYFKNHTWLKSYLLEKIKEHEESLDVSNP-RDFIDYFLIE-----------------RNQENANQWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFIPFSA---------GKRMCLGESLARMELFLFLTTILQNFKLKSL-VDPKDINTTPICSSLSSVPPTFQMRFIPL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24470-1", "uniprot_id": "CP2CN_RAT", "id": "P24470-1", "name": "Cytochrome P450 2C23", "aln": "----------MELLGF-----------------------------TTLALVVSVTCLS---LLSVWTKLRTRGRLPPGPTPLPIIGNLLQLNL--KDIPASLSKLA---KEYGPVYTLYFGT-SPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDT---HKGYGLIFSNGE-RWKVMRRFSLMTLRNFGMGKRSLEERVQEE----------ARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIK----------------------------YLPGKHIEFAKRIDDVKNFILEKVKEHQKSLDPANP-RDYIDCFLSK-----------------IEEEKDNLKSEFHLENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSL---------GKRACVGESLARMELFLFFTTLLQKFSLKTL-VEPKDLDIKPITTGIINLPPPYKLCLVPR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5K4-1", "uniprot_id": "CP2CN_MOUSE", "id": "E9Q5K4-1", "name": "Cytochrome P450 2C44", "aln": "----------MELLGL-----------------------------PTLALLVLVMSLS---LLSVWTKMRTGGRLPPGPTPLPIIGNILQLDL--KDIPASLSKLA---KEYGPVYTLYFGS-WPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDS---QKGHGIVFSEGE-RWKLLRRFSLMTLKNFGMGKRSLEERVQEE----------ARCLVEELHKTEAQPFDPTFILACAPCNVICSILFNERFPYNDKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMK----------------------------YIPGKHREFSKRLGGVKNFILEKVKEHQESLDPANP-RDYIDCFLSK-----------------IEEEKHNLKSDFNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKHPEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRHYVIPKGTAVFPFLSSILLDQKEFPNPEKFDPGHFLDKNGCFKKTDYFVPFSL---------GKRSCVGEGLARMELFLFFTTILQKFSLKAL-VEPKDLDIKPVTTGLFNLPPPYKLRLVPR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05182-1", "uniprot_id": "CP2E1_RAT", "id": "P05182-1", "name": "Cytochrome P450 2E1", "aln": "----------MAVLG------------------------------ITIALLVWVATLL---VISIWKQIYNSWNLPPGPFPLPILGNIFQLDL--KDIPKSFTKLA---KRFGPVFTLHLGS-RRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEY---KN-KGIIFNNGP-TWKDVRRFSLSILRDWGMGKQGNEARIQRE----------AQFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYNDKKCLRLMSLFNENFYLLSTPWIQLYNNFADYLR----------------------------YLPGSHRKIMKNVSEIKQYTLEKAKEHLQSLDINCA-RDVTDCLLIE-----------------MEKEKHSQEPMYTMENVSVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRVPAVRDRLDMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFQGYVIPKGTVVIPTLDSLLYDSHEFPDPEKFKPEHFLNENGKFKYSDYFKAFSA---------GKRVCVGEGLARMELFLLLSAILQHFNLKSL-VDPKDIDLSPVTVGFGSIPPQFKLCVIPRS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05421-1", "uniprot_id": "CP2E1_MOUSE", "id": "Q05421-1", "name": "Cytochrome P450 2E1", "aln": "----------MAVLG------------------------------ITVALLVWIATLL---LVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDL--KDIPKSLTKLA---KRFGPVFTLHLGQ-RRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEY---KN-KGIIFNNGP-TWKDVRRFSLSILRDWGMGKQGNEARIQRE----------AHFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQ----------------------------YLPGSHRKVMKNVSEIRQYTLGKAKEHLKSLDINCP-RDVTDCLLIE-----------------MEKEKHSQEPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGKFKYSDYFKAFSA---------GKRVCVGEGLARMELFLLLSAILQHFNLKSL-VDPKDIDLSPVTIGFGSIPREFKLCVIPRS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05181-1", "uniprot_id": "CP2E1_HUMAN", "id": "P05181-1", "name": "Cytochrome P450 2E1", "aln": "----------MSALG------------------------------VTVALLVWAAFLL---LVSMWRQVHSSWNLPPGPFPLPIIGNLFQLEL--KNIPKSFTRLA---QRFGPVFTLYVGS-QRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH---RD-RGIIFNNGP-TWKDIRRFSLTTLRNYGMGKQGNESRIQRE----------AHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLH----------------------------YLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCP-RDLTDCLLVE-----------------MEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFST---------GKRVCAGEGLARMELFLLLCAILQHFNLKPL-VDPKDIDLSPIHIGFGCIPPRYKLCVIPRS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10633-1", "uniprot_id": "CP2D1_RAT", "id": "P10633-1", "name": "Cytochrome P450 2D1", "aln": "----------MELLN-----------------------------GTGLWSMAIFTVIFILLVDLMHRRHRWTSRYPPGPVPWPVLGNLLQVDL--SNMPYSLYK---LQHRYGDVFSLQKGW-KPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKE----------AGHLCDAFTAQAGQSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMVKLVEESLTEVSGFIPEVLNTFPALLR-----------------------------IPGLADKVFQGQKTFMALLDNLLAENRTTWDPAQPPRNLTDAFLA-----------------EVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPHRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQRFSFSVP--VGQPRPSTHGFFAFPVAPLPYQLCAVVREQGL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12939-1", "uniprot_id": "CP2DA_RAT", "id": "P12939-1", "name": "Cytochrome P450 2D10", "aln": "----------MELLN-----------------------------GTGLWPMAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDP--SNMPYSMYK---LQHRYGDVFSLQMGW-KPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVVFASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKE----------AGHLCDAFTAQNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVSGFIPEVLNTFPALLR-----------------------------IPGLADKVFQGQKTFMAFLDNLLAENRTTWDPAQPPRNLTDAFLA-----------------EVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQHFSFSVP--AGQPRPSTLGNFAISVAPLPYQLCAAVREQGH------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7UVB4-1", "uniprot_id": "A0A8N7UVB4_DANRE", "id": "A0A8N7UVB4-1", "name": "", "aln": "----------MAVVE-------------------SLLQFA----STGTLLGALLLFLVLYLVSSGSESQK-EGKEPPGPKPLPLVGNLLTLDL--TRPFDTFFK---LSKTYGNVFQVYLGP-EKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIM---NDEHGILFS-NGENWKEMRRFALSNLRDFGMGKRGSEEKIIEE----------IHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFPWLG-----------------------------PFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDP-RGFVDSFLIRK---------------LSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSA---------GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRRS---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BB11-1", "uniprot_id": "A0A8M2BB11_DANRE", "id": "A0A8M2BB11-1", "name": "", "aln": "----------MAVVE-------------------SLLQFA----STGTLLGALLLFLVLYLVSSGSGSQK-EGKEPPGPKPLPLLGNLLTLDL--TRAFDTFFE---LSKTYGNIFQVYLGP-KKTVVLVGYKTVKEALVNHAEAFGDREIGPSFRIM---NDEHGIVFS-NGENWKEMRRFALSNLRDFGMGKRGSEEKIIEE----------IHHLKGEFDKFEGKPFDTTEPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMGLYNMFPWLG-----------------------------PFLKNKRIVVRNIIQSRAQMTKLITALLETLNPNDP-RGFVDSFLIHK---------------LSDEKSGKKNSYFHNENLMMNVANLFVAGTDTTGTTLRWGLMLMAKYPQIQDRVQEEIDRVIGG-RQPAVEDRKKLPYTDAVIHEIQRFANIVPLNLPHTTSCDITFNGYFIKKGTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA---------GRRICLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PP30-1", "uniprot_id": "A0A8M9PP30_DANRE", "id": "A0A8M9PP30-1", "name": "", "aln": "----------MAVVE-------------------SLLQFA----STSALLGALLLLLVLYLASSGSTSQK-EGKEPPGPKPLPLVGNLLTLDL--TRSFDTFFE---LSKTYGNIFQVFLGH-RKTVVLVGYKTVKEALVNYAEVFGDREIGPGFKLK---DEEHGILFS-NGENWKEMRRFALSNLRDFGMGKRGSEEKIIEE----------IHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYIDPRFTEMVARANENVRVGGSFSMMIYNIFPWLG-----------------------------PFLKNRAVVVKNITQNRAEKKKLITALLETLNPHDP-RGFVDSFLIHK---------------LSDEKSGKKDSYFHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVDDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA---------GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDALDLKGIVGITLNPSPHKLCAIRRS---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F7FAJ1-1", "uniprot_id": "F7FAJ1_RAT", "id": "F7FAJ1-1", "name": "Vitamin D 25-hydroxylase", "aln": "----------MGVRQGWKARPGLSETNWFPPQPWPMFQLPGVQTCAGALAGAFLLLLLVLVVRQLLRQRR-PAGFPPGPPRLPFIGNICSLAL--SADLPHVYMRK-QSRVFGEIFSLDLGG-ISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKM---TKMGGLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEE----------TWSLIDAIETYKGRPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGIL---------------------------PFGKHQR-LFRNADVVYDFLSKLIEKAAVNRKPHLP-QNFVDAYLD-----------------EMDKGQNDPLSTFSKENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGQVHKEIDLIMGHDRRPSWEDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSSGYFTKKEALIPFSL---------GRRHCLGEQLARMEMFLFFTSLLQQFHLHFP---HELVPNLKPRLGMTLQPQAYLICAERR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "S4R196-1", "uniprot_id": "S4R196_MOUSE", "id": "S4R196-1", "name": "unspecific monooxygenase", "aln": "---------------------------------------------MFSLFSGMAFLAGSCLLLKLATLCWRRSHLPPGPFPFPLLGNLWQLNF--QLHPNMLFQLA---QTHGSVFTVWLGS-TPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFRDL---FGEKGVICSNGL-TWRQQRRFCLTTLRELGLGKQALEVQLQHE----------AAELAKVFLQEEGRAFDPQIPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALR----------------------------HLSGPHQKIFQYHEAVRGFIRHEIIRHKLR-TAEAP-KDFINCYLSQ-----------------ITKAIDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWALIYLVHHRAIQERVQQELDEMLGAAQTICYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGNFVANEAFLPFSA---------GHRVCPGEQLARMELFLMFATLLRTFQFQLP-EGSQDLGLEYVFGGTLQ-PQPQKICAVLRQSSLSPREP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZX4-1", "uniprot_id": "D3ZZX4_RAT", "id": "D3ZZX4-1", "name": "unspecific monooxygenase", "aln": "---------------------------------------------MFSLFGGMAFLAGSFLLLKLAALCWRRSHLPPGPFPFPLLGNLWQLNF--RLHPNMLFQLA---QTHGNVFTVWLGS-TPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDL---FGEKGVICSNGL-TWRQQRRFCLTTLRELGLGKQALELQLQHE----------AAELAEVFHQEQGRAFDPQVPIIRSTTRVIGALVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLYDMFPWALR----------------------------YLSGPHQKIFQYHEAVRGFIHHEIIRHKLR-TPEAP-KDFISCYLSQ-----------------ITKAMDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWAIIYLVHHRAIQERVQQELDEVLGTAQAVCYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGYYVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSA---------GHRVCPGEQLARMELFLMFATLLRTFRFQLP-EGSQGLRLEYVFGGTLQ-PQPQKICAVPRLSSLSPREP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWR5-1", "uniprot_id": "CP306_DROME", "id": "Q9VWR5-1", "name": "Cytochrome P450 306a1", "aln": "MSADIVDIG---------------------------HTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDA--RAPHKSLQKLA---KRYGGIFELKMGR-VPTVVLSDAALVRDFFRR--DVMTGRAPLYLTHGIMG---GFGIICAQED-IWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELL---LPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSS---------GYRMCPGEEMARMILTLFTGRILRRFHLELP---SGTEVDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** ...* . . * : : . ::: :: : . * *. *. : :: * : * . . : . .: : : : . : : : :: * : : .: : : : : :.* * : * * . . . . : .. : : . : * .** .:: * * * * :.: : : ::: . ", "identical_positions": 23, "similar_positions": 71, "identity": "3.66%" }, { "cls_id": "homologset.agr.FB:FBgn0005198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49816-1", "uniprot_id": "TSC2_RAT", "id": "P49816-1", "name": "Tuberin", "aln": "MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITAEILRELSGECGLNNRIRMIGQICDVAKTKK-LEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLRALFFKVIKDY-PSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWM----DVGLSSEFLLVLVNLVKFNSCYLDEYIAP-MVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIITLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMENRSYMEDAPLLRGAVFFVGMALWGAHRLYSLK--NSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLDIIERLLQQLQNLDSP--------ELRTIVHDLLTTVEELCDQN--EFHGSQERYYELVESYADQRPESSLLNLITYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPP----------LELEERDLAVYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYETLISHIQLHYKHGYSLPIASSIRLQAFDFLLLLRADSLHRLGLPN-KDGVVRFSPYCLCDCAELD-RASEKKASGPLSPPTGPPSPVPTGPAVRLGHLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYKVLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLP-HLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDKFRARSTSLNERPKSLRIARAPKQGLNNSPPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGDLQGGSASS-----------------SDPGTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG-------VLDTSAPYTPGGPASLGA-------QAAPAARPEKPCAGAQLPAAEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLS--------PFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAG---------------TAKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAVVL---------------------EEGSPGEAHVPVEPPELEDFEAALG----TDRHCQRPDAYSRSSSASSQEEKS-HLEELAAGGIPIER---AISSEGARP---TVDLSFQPSQPLS----------KSSSSPELQTLQDILGDLG-----------DKTDIGRLSPEAKVRSQSGILDGEAATWSAPGE------ESRITVPPEGPLPSSSPRSPSG----LRPRGYTISDSAPSRRGKR--VERDNFKSRTAASS-AEKVPGINPSFVFLQLYHSPFCGDESNKPILLPNES--FERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCD-KKRHLGNDFVSIIYNDSGEDFKLGTIK-GQFNFVHVIITPLDYKCNLLTLQCRKDMEG------LVDTSVAKIVSDRNLSFVARQMALHANMASQVHHRRSNPTDIYPSKWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHT---KVPAQAPTEATPTYETGQRKRLISSVDDFTEFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61037-1", "uniprot_id": "TSC2_MOUSE", "id": "Q61037-1", "name": "Tuberin", "aln": "MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITSEILRELSGECGLNNRIRMIGQICDVAKTKK-LEEHAVEALWKAVSDLLQPERPPEARHAVLTLLKAIVQGQGDRLGVLRALFFKVIKDY-PSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWM----DVGLSSEFLLVLVNLVKFNSCYLDEYIAS-MVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRSYMEDAPLLRGAVFFVGMALWGAHRLYSLK--NSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLDIIERLLQQLQNLDSP--------ELKTIVHDLLTTVEELCDQN--EFHGSQERYYELVESYADQRPESSLLNLISYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVAIKVLDVLSFVLLIIRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPP----------PELEERDLAVHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYESLISHIQLHYKHGYSLPIASSIRLQAFDFLLLLRADSLHRLGLPN-KDGVVRFSPYCLCDCMELD-RASEKKASGPLSPPTGPPSPVPMGPAVRLGYLPYSLLFRVLLQCLKQESDWKVLKLVLSRLPESLRYKVLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLP-HLYRNFVPEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARAPKQGLNNSPPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGDLQGGSDSS-----------------SDPSTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG-------VLDTSAPYSPGGSASLGP-------QTAVAAKPEKPPAGAQLPTAEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLS--------PFSSDINNMPLQELSNALMAAERFKEHGHAPVQVIVSATGC----------------TAKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAMVL---------------------EEGSPGETQVPVEPPELEDFEAALG----TDRHCQRPDTYSRSSSASSQEEKS-HLEELAAGGIPIER---AISSEGARP---AVDLSFQPSQPLS----------KSSSSPELQTLQDILGDLG-----------DKIDIGRLSPEAKVRSQSGILDGEAATWSATGE------ESRITVPPEGPLPSSSPRSPSG----LRPRGYTISDSAPSRRGKR--VERDNFKSRAAASS-AEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNES--FERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCD-KKRHLGNDFVSIIYNDSGEDFKLGTIKQGQFNFVHVIITPLDYKCNLLTLQCRKDGPACKCEWWRQPGEIVVWALPVVMELTVTILLCHLQMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHT---KAPAQAP-EATPTYETGQRKRLISSVDDFTEFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49815-1", "uniprot_id": "TSC2_HUMAN", "id": "P49815-1", "name": "Tuberin", "aln": "MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKK-FEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDY-PSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWM----DVGLSSEFLLVLVNLVKFNSCYLDEYIAR-MVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLR--NSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSP--------ELRTIVHDLLTTVEELCDQN--EFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPP----------PELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPN-KDGVVRFSPYCVCDYMEPE-RGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLP-HLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESS-----------------SSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG-------ALDVPASQFLGSATSPGP-------RTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLS--------PFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAS---------------TAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVM---------------------EEGSPGEVPVLVEPPGLEDVEAALG----MDR---RTDAYSRSSSVSSQEEKSLHAEELVGRGIPIER---VVSSEGGRP---SVDLSFQPSQPLS----------KSSSSPELQTLQDILGDPG-----------DKADVGRLSPEVKARSQSGTLDGESAAWSASGE------DSRG--QPEGPLPSSSPRSPSG----LRPRGYTISDSAPSRRGKR--VERDALKSRATASN-AEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCD-KKRHLGNDFVSIVYNDSGEDFKLGTIK-GQFNFVHVIVTPLDYECNLVSLQCRKDMEG------LVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHS---KAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PW15-1", "uniprot_id": "A0A8M9PW15_DANRE", "id": "A0A8M9PW15-1", "name": "Tuberin", "aln": "MNKQPSKES-LRDKFKGIFGLGPTRPHHKQADNKPSEYIITLDILMELTSEYSLNHRIRMVNHVCELAKTKR-FEEHAVEAIWKAVEDLTQPEQPPEARHAVLVLLRAIIQGQGEWLGPLRAYFFKVILDYQPSNEELPERLEVFKALTENGKDITYLEEEIARFVLLWM----ENGLSSDFLHVLVNLVKFNSCYLDENVSL-MVQKICLLCNRTTSSTDIEVALQVLDAVVCYNCLPSDSLTVFIITLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEERVYSEDAALLRGAVFFVGMALWGAHRLPALK--NTPTLVLPSFYKAMSCANEVVSYEIVLSITRLIKKYGRELQVVTWDILLSIIDRLLQQIQTMGSP--------DLKVIVYELLSTIEELYEQN--DFHGSSARFFSLVEKCADKRPDASVLTLVSYRAQAIQPAKDGWLQNLLKLMDKFFRNESRTMIRIKVLHILSFVLSTNRQLYEEELIEVVVIPQLGQIAEDRDPSVRKQATQLLVDLAEGCSTHHFSSLLDIIEKVASRPLSCS----------VEGD-RELCVESP-LEDVRTAILGLLDILQSKLYSLPASHASRVYELLISHLQLHYKNKYCSAISGAIRLKVFDFLLLMRADSLHRLGVPN-KDGALRFSPYCHCDPGESEKRVSEKKPTGSVSPPAGSPTPAAPPSSIRTAYLPYSLAFSVLLQCLKTETDWKVLKLVLDKMSCTIQYKVLILTSPCNIDNLCATLCSMVTDRIILERLKKTPDGFSLTDVQLAVVPVLTAITSYHSYLDQLRQRDLVQCLEKGLIYRCAKQCVVALTMCTVEMPDIMIKLLPALIVKLTHISATVAMASPMLEFLSTLVRLP-HLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLAHHVIAMWFIRCRLPFRKDFVQYITKGLRSNALLPFDDTHEQSSFRARSTSLNERPKSLRTTKVAKQGPSANSPVKDLKDLSAMDAFRSRSISVSEHAVR-RMQTSSTTCSLGSADENAVMQADDALKTVHLELTETCLDMMARYVFSNFSALPKRSPIADFLLSGGPSMTWLVGNKLVTITTSGGSRTQALLGLDMTERHGGGEMTR----------------SDPSLHTRQTKEAPAKLESQSSQQINTNTRTRVRSISGGHALRAGPAQSLSPLVASPEGEYSGPLPPPGPPLDVLSSQRGMEEHPPPSACNPSPPLKHKHSLAEFVPMLTQGWAEIFIRRPSGNTSWLMCLENPPS--------PFSSELGNLPLQELSSVLMAMDGVKEP-PAERPTDVSQPQG------------------KPAPIQRSNTVASLSSLCSSESSGRFHRSISWADSVVME---------------------ESGRSMASVSPAESKEVEEFEAVPSEPIFMNTSTTAPGMMSRSSSTSSQDDDKSTLEEVSEGGIPIDQPPLSLCTPGAQDPELSFTQSSSSSSTLN----------KSSSSPELQTLPEAFSKASSQS-------VDPAPTSKIPTVQACVEAPGESAGSTAGTSCSSSSVSVSSSSTSRMRLEFPPVQTGPLSPTG----HRPRGHTISVSAPSSRRDRKTLERD---ARGGATN-VEKSSGLSPSFVFLQLYHSPFFGNEANKPLLLPKSQ-LIDRAVKVLDQMPPYDTHKIGVVFVGAGQANNEVSILSNEYGSKRYAQFLTGLGKLIHLKDCDPDQIFLGGLDQYGDDGEFTYCWHDDIMQAIFHIATLMPNRESDRGCCN-KKRHIGNDFVVVVYNDSGEDYKLGTIK-GQFNFVEVLIKPLDYESNLVTLQCRKDLEG------LVDTSVAKIVSDRNLPLLVRQMALHANMASLVHQCRANPSDAYASKWLARLRHIKRIRTRAQEEIQ-SRPSHGISLTQGHASMQNKPAHQPPGAAQNPDAGQRKRLVSTVDDFTDFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW83-1", "uniprot_id": "Q9VW83_DROME", "id": "Q9VW83-1", "name": "", "aln": "------MNSKDKSKFKLFLKS--------LPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNH-EAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKR--QLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYR-MSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDS--------------------------PLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGN--DIEELANTLLKIN-------LVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSIQSNAKMLSSDIVNLNSLNEDSSNRK------------------------------------RSTSLTERGSRNNANAWN--------DLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENS----SAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIM-LDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTIS-GQFNYACVIVEPLDLNSNRVYVKARSEISK------FVCHAEYRIVSDRSAPLLARQMALHANLASLVYQS-VQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGIN-----------------ASAIGSDMDDQRGDFIKYT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :.*** :: . . * : :: ** * : :* **: .: : : ::* *: ::: . ** *::* *:*: .* : : ::: * . * :* ** ** :: :.*:* . **::.:**:**:.** :**::. *:* *: : .* : :* :****:***:.:**: : :*: * *. .. . .* :*: *: *. :*::.*. * *****:* * ..:*:*:::***:**: :: ** ::::* :** *******.:.* ::*:: : : . .* **.:* .*: . : :*::*::**: :*.* :*. : **:: .*:. ::.::: . .*: .:: : :*:* :*: :: *. * :.*:* **:**::*:* *: **:: : .:: .*:* * :: :::* .. : **.:. * :: * ****::. **: :*.:* : . .** .:: * ::* * *:: .****:* : *.:. . : .. :.*: :*: **: :: **: **. ** :::: *:.*::***:. . :* : * :** **:. :::* *: . .::**** * . . : :. ::::**: ::*::*::**: .:. :: *.*: . .:::*. :* .: : . :.: *:*.:::: **. *: :: :: .*:. :: *. *: :::: :***: ::: ** ::::::::* * ::* *:***** * :*. **: **.. : ****:****:* ::::* *.******* **::*:* :*:: * :*...::**. : .* : ..:. *:. : ** *::*: * . :: * : * :: *:..* **:***:*::**:.:* .::*** * .:*** .* : ******:***:*** . : : ** : * : . :.: : : .: ** .. ::. .: . : .* : . . . . .. . . * . ****:::***:**.**: ::** : **.. :. : ...: . : .: : . *. .: *.: : *... . . .*. . . :... ..* . * . :.. : ..... .:: : :.:.: .: . : :. . * . . ..: .*: :: : .. . :.. .* . . .* . . .* * *. *** . . . *. :. :.***:*:*** : * : : *:.. :*.::* :*.::****.*::** **...*: ** *.:** **.:** .:* *: **:.: ::::: ** * **:*:* *:***:*. **:*****.. * *: ** *:***** ::**:***:::*.**. ****:. *:: *** :.* : ::.*.: . : . : * ::** *:: : .. *.*:*: ***::**:* : * .. * . . . : . ** .:.", "identical_positions": 422, "similar_positions": 616, "identity": "21.38%" }, { "cls_id": "homologset.agr.FB:FBgn0005278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18298-1", "uniprot_id": "METK2_RAT", "id": "P18298-1", "name": "S-adenosylmethionine synthase isoform type-2", "aln": "MNGQLNG-----------FHEAFIEEGTFLFTSESVGEGHPDKICDQINDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVISVQHDEEVCLDEMRDALKEKLIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSER-ELLEIVKNNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3THS6-1", "uniprot_id": "METK2_MOUSE", "id": "Q3THS6-1", "name": "S-adenosylmethionine synthase isoform type-2", "aln": "MNGQLNG-----------FHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSER-ELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31153-1", "uniprot_id": "METK2_HUMAN", "id": "P31153-1", "name": "S-adenosylmethionine synthase isoform type-2", "aln": "MNGQLNG-----------FHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSER-ELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91X83-1", "uniprot_id": "METK1_MOUSE", "id": "Q91X83-1", "name": "S-adenosylmethionine synthase isoform type-1", "aln": "MNGPVDGL----------CDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSNKTER-ELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13444-1", "uniprot_id": "METK1_RAT", "id": "P13444-1", "name": "S-adenosylmethionine synthase isoform type-1", "aln": "MNGPVDGL----------CDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMIDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRMADLRRSGVLPWLRPDSKTQVTVQYVQDNGAVIPVRVHTIVISVQHNEDITLEAMREALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSKKTERDELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00266-1", "uniprot_id": "METK1_HUMAN", "id": "Q00266-1", "name": "S-adenosylmethionine synthase isoform type-1", "aln": "MNGPVDGL----------CDHSLS-EGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTER-ELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40320-1", "uniprot_id": "METK_DROME", "id": "P40320-1", "name": "S-adenosylmethionine synthase", "aln": "MPQKTNGHSANGCNGSNGNSYDMEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGTSHKSQK-ELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPLEIDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10659-1", "uniprot_id": "METK1_YEAST", "id": "P10659-1", "name": "S-adenosylmethionine synthase 1", "aln": "------------------------MAGTFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACETAAKTGMIMVFGEITTKAQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGVHEEKDLEDIGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLAWLRPDTKTQVTVEYKDDHGRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVIPRDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDE-EIIDIISKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYPWEKPKTLKF--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19358-1", "uniprot_id": "METK2_YEAST", "id": "P19358-1", "name": "S-adenosylmethionine synthase 2", "aln": "----------------------MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAKTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGLHYEKSLEDLGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLPWLRPDTKTQVTVEYEDDNGRWVPKRIDTVVISAQHADEISTADLRTQLQKDIVEKVIPKDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDD-EIIEIIKKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYSWEKPKKLEF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:*************:***:.**:*** * :** :******..****::: ****: * :***::**:::::******:****:******:*::****:** :* :: *::******:********* * :***::****** :*: **.. : * ***:***** :* :.* :* *:.*:*:* ** :.: :: : ..::. *:* . :* :* .::*.* ****** ****:********:*** .: *********::****************** .***:* **.*****::.***: : ***: *:: *::::: .******* :*::*:* :*** *: **** . :.** .: * ", "identical_positions": 210, "similar_positions": 104, "identity": "51.34%" }, { "cls_id": "homologset.agr.FB:FBgn0005322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NBU5-1", "uniprot_id": "ATAD1_HUMAN", "id": "Q8NBU5-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMKQIG------VKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDR-HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST-------------SEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQN---VLTHVCLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D5T0-1", "uniprot_id": "ATAD1_MOUSE", "id": "Q9D5T0-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMKQIG------VKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDR-HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST-------------SEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQN---VLTHVCLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q505J9-1", "uniprot_id": "ATAD1_RAT", "id": "Q505J9-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMKQIG------VKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDR-HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST-------------SEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQS---VLTHVCLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q503W7-1", "uniprot_id": "ATD1B_DANRE", "id": "Q503W7-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "MVLKEIPTENITRPLGRNEVIGLLFRLTIFGAVTYFTIKWMVDAIDP------TRKQKVEAQKQAEKLMRQIG------VQNVKLSEYEMSIAAHLVDPLTMQITWHDIAGLDEVITELKDTVILPIQKRHLFEGSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGFRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDYNCQVIIMGATNRPQDLDSAILRRMPTRFHINQPNVRQRKDILKLILENENVES-AVELSEIAKQTDGFSGSDLREMCRDAALLCVRDFVH----------------QESPEEDFIRPIRQEDLQRAIEKMKKSKSAGVHE---AFMQVPLD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZZ25-1", "uniprot_id": "ATD1A_DANRE", "id": "Q7ZZ25-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "-MLSDIPRDALLRPLTRNEVVGMLVRLTVFGAATYYSIKWVVDALDP------TQKQKSQAKKRAEQLMKQIG------VEGVSLTEYEMNIATLLVDPRSIKVTWRDVAGLDEIISEMQDTVILPFQKRHLFSGSKLLQPPKGVLLYGPPGCGKTLIAKATAKASGCRFINLQASTLTDKWYGESQKLTAAVFSLAVKIQPCIIFLDEIDSFLRNRSSMDHEATAMMKAQFMSLWDGLDTGENSQVMVMGATNRPQDVDAAILRRMPTAFHVGLPNAAQREEILRLILSGENLSN-AINLKEIASQSEGYSGSDLKELCRDAAMYRVRDYVRKQQMKQIAQQFQLDEEEEHVDSRQLRPVTQLDLLFGLDKMRESKQATATTDPANLREVPLD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL02-1", "uniprot_id": "Q9VL02_DROME", "id": "Q9VL02-1", "name": "", "aln": "----MDNFGLGGSDLSKGQIFQVLVRLSVASLITYYSVKWMMNQMDP------TSKNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEVSQ-DVDLNRLSKLTNGFSGSDLREMCRNASVYRMRQLITSR-----------DPSATALDRNNVR-ITMDDLLGSHLKIKESKMHTSSL--FLENRIELD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28737-1", "uniprot_id": "MSP1_YEAST", "id": "P28737-1", "name": "Outer mitochondrial transmembrane helix translocase", "aln": "----------MSRKFDLKTITDLSV-LVGTGISLYYLVSRLLNDVESGPLSGKSRESKAKQSLQWEKLVKRSP-----ALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFMTLWDGLLN--NGRVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQK--------------RQLIDSGTIDVNDTSSLKIRPLKTKDFTKKLRMDATSTLSSQPLD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . * . *: :. ::: ::. : :.* : . *: ::: : : ** * : :* * : ::: *:.*** :* :::::*: *: .::. * * *.*.****:********::*** ** :* .**.: : : *******:*:. *:**** :::*.***:********.*. ***.** :*::** ***** . . *:::***** :*:* *::**:* * :. * ** ** ::*.. ::. .:* ::. :.*:*****:*:**:*:: :: : : : .* * :. . **", "identical_positions": 113, "similar_positions": 112, "identity": "28.68%" }, { "cls_id": "homologset.agr.FB:FBgn0005355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A606-1", "uniprot_id": "A0A8I6A606_RAT", "id": "A0A8I6A606-1", "name": "Suppressor of fused homolog", "aln": "MAELRPSVAPGPAAPPASGPSAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNMGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKR---------ETGES--APPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLD-NSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICLGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINSQRQNGLTYDRAPSRKDSLGSDISTAVIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPE--EFKLPKEYSWPEKKLKVSI------LPDVVFDSPLH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0P7-1", "uniprot_id": "SUFU_MOUSE", "id": "Q9Z0P7-1", "name": "Suppressor of fused homolog", "aln": "MAELRPSVAPGPAAPPASGPSAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNMGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKR---------ETGES--APPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLD-NSESRIQHMLLTEDPQMQPVRTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDEEDSRSICLGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINSQRQNGLTHDRAPSRKDSLGSDSSTAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPE--EFKLPKEYSWPEKKLKVSI------LPDVVFDSPLH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMX1-1", "uniprot_id": "SUFU_HUMAN", "id": "Q9UMX1-1", "name": "Suppressor of fused homolog", "aln": "MAELRPSGAPGPTAPPAPGPTAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKR---------ETGES--APPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLD-NSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINPQRQNGLAHDRAPSRKDSLESDSSTAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLTSPE--EFKLPKEYSWPEKKLKVSI------LPDVVFDSPLH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG38-1", "uniprot_id": "Q9VG38_DROME", "id": "Q9VG38-1", "name": "Suppressor of fused homolog", "aln": "MAEANLDKKP-EVKP---------------PPGLKAIIDHLGQVYPNQPNPLQVTTLLKYWLGGQDPLDYISMYNYPGDVDRNVPPHWHYISFGLSDLHGDERVHLREEGVTRSGMGFELTFRLAKTEIELKQQIENPEKPQRPPTWPANLLQAIGRYCFQTGNGLCFGDNIPWRKSLDGSTTSKLQNLLVAQDPQLGCIDTPTGTVDFCQIVGVFDDELEQASRWNGRGVLNFLRQDMQTGGDWLVTNMDRQMSVFELFPETLLNLQDDLEKQGSDLAGVNADFTFRELKPTKEVKEEVDFQALS--EKCANDENNRQLTDTQMK----REEPSFPQSMSMSSNSLHKSCPLDFQAQAPNCIS-------------LDGIEITLAPGVAKYLLLAIKDRIRHGRHFTFKAQH--LALTLVAESVTGSAVTVNEPYGVLGYWIQVLIPDELVPRLMEDFRSAGLDEKCEPKERLELEWPDKNLKLIIDQPEPVLPMSLDAAPLKM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** . . * . * ****:** .. ::**:********:::****** *****:***. *. . *:* ************:**:*** **:******** : *. *. ******:*:*.:.** **: * :* **::.*:..** .: *::*::*:::***: : ** *.* * ***** :**..*.:***:*:*::** :** **:*:* * ::**: *. .::..:*.:**:*:**.*. :: :*. . * .*: .:. : ..::..*: :* : ..:* :* . .*.* . . . : . . * *:.:.:.: . : *.::.*: ******:*: :*:*:*: .* *: .* :.**.. * *:*:*:.:*:* :::**:.. * * * * .**:*:**: * ** : :**: ", "identical_positions": 179, "similar_positions": 155, "identity": "35.45%" }, { "cls_id": "homologset.agr.FB:FBgn0005386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKH4-1", "uniprot_id": "D3ZKH4_RAT", "id": "D3ZKH4-1", "name": "Histone-lysine N-methyltransferase ASH1L", "aln": "MDPRNTAMLGLGSDSEGFSRKSPSAISSGTLASKREVEIEGNT-DEEDPRKRNRERAIEAGKDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTVKHSRKALKSGKMTDEKNEHCPSKWDSSKLFKKAGDATAIECQSEESVHLHSQGENNPLSKKLSPVHSQMADYIPAAP-PLVGSRDPDIKDRALLNGGTSVTEKLAQLIATCPPSKSSKAKPKKLGTGTTVGLVSKDLIRKPGVGSIAGIIHKDLIKKPALSTAVGLVTKDPGKKPMFNAAVSLINKDSVKKLGTGTTAVFINKDLGKKPGTVTTVGLLSKDPGKKLGIGIVPGLVNKESGKKLGLGTVVGLVNKELGKKLSSTVGLVAKDVTKKIVASSAMGLVNKDIGKKLLSCPIAGQLGSKDALNLKSEALLPTQEQLKASCSANISNHESQELPESLKDSATSKTFEKNVMRHSKESMLEKFSVRKEITNLEKEMFNEGTCIQQDSFSSNERGAFETSKHEKQPPVYCTSPDFQIGGASDASTAKSPFGAVGESNLPSSSPTVSVNPLTRNPPETSSQLVPNPLLLNSTAEQMEEISESIGKNQFTAESTHLNVGHRSLGHSISIECKGIDKELNESKSTHLDISRISSSLGKKPSLASDSGIHTITP-SVVNFTSLFSNKPFLKLGAVAAPDKHCQVAESLSTSFQSKPLKKRKGRKARWTKVVARSTCRSPKGLDLERSELFKNVSCSSLSNS-SEPAKFMKTIGASSFVDHDFLKRRLPKLSKSSAPSLALLADSEKASHKSFITHKLSSSMCVTSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESENHRSSSDFFESEDQLQDTDDLEDSHRQSVCSVSDLEMEPDKKISKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGLLSGSPASLAVLEQTAQQAAGSALGQILPPLLPSPASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHVHSRQGSMIQTLAMKKAAKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHISLIPPETSTVLNSLKEKHKHKCKRRSHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPTKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRS-EQPQVSMDTGSSRSVLESLKRYRFGKDTVGDRYKHKEKHRCHMSCPHLSPSKSLINREEQWVSREPSESSSLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHMNLFTSAIGSCRVSNPNSSCRKKLTDSPGLFPVQDTALSRPHRKEPLPSTERAIQSLAGSQSASDKPSQRSSESTNCSPTRKRSSSESTSSTVNGIPSRSPRLVASLDDSVDCLLQRIVQHDEQESVEKNGDAPITTVSAPPSSSPGHSYSKERTLGKSDSLLVPAVPSDSCN-SIPLLSEKLASRCSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNEGEE-VSLHLSPDTVTDVIEAVVQSVNLNSEHKKGWKRKNWLLEEQTRKKQKTVPEEEEQENNKSFIEKPVEIPSPLETPAEPSEPESNLQPVLALIPREKKAPRPPKKKYQRAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHV-----GKYLRQKRIDFQLPYDILWQWKHNQLYKKPDVP--LYKKIRSNVYVDVKP--LSGYEATTCNCKKPDDDTRKGCGDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDVPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRMNGLPSHKGSQPASTHRKSARSKEKRKSKHKLKKRRGHPSEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIHQKQEEVKHSRD-IHSTSLYTRWNG--ICRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKEICDGIISYKDSSQQALAAPLLNLPPKKKNADYYEKISDP--LDLSTIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYSARHEASAQIDEIVGET------------ASEADSSETSVSEKENSHEKD---------------------DDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDG----HPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVK-EQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKRDFSPHYVPDNYKRNGGRSSWKSERSKPLLKDLGQDDDALPLIEEVLASQEQAANEMPSPEEPDQERVTGDVSDAEKKPEESSQEPQLASTPEERRHSQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPENSFRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MY8-1", "uniprot_id": "ASH1L_MOUSE", "id": "Q99MY8-1", "name": "Histone-lysine N-methyltransferase ASH1L", "aln": "MDPRNTAMLGLGSDSEGFSRKSPSTINPGTLASKREAEIEGAT-EEEDPRKRNRERGTEAGKEDGSTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHSRKALKSGKMTDEKNEHCPSKWDSSKLFKKAGDATAIDCQAEESIHLHSQGESNPLSKKLSPVHSQMADYISAAP-SLVGSRDPDIKDRALLNGGTSVTEKLAQLIATCPPSKSSKAKPKKLGTGTTVGLVSKDLIRKPGVGSIAGIIHKDLIKKPALSTAVGLVTKDPGKKPMFNAAVGLINKDSVKKLGTGTTAVFINKDLGKKPGAITTVGLLSKESGKKLGIGIVPGLVNKESGKKLGLGTVVGLVNKELGKKLSSTVGLVAKDVTKKIVASSAMGLVNKDIGKKLLNCPMAGQLGSKDALNLKSEALLPTQEQLKASCSANISNHDSQELPESLKDSATGKAFEKSVMRHSKESMLEKFSVRKEITNLEKEMFNEGTCIQQDNFSSSERGAFETSKHEKQPPVYCTSPDFQIGGASDASTAKSPFSAVGESNLPSSSPTVSVNPVTRSPPEASSQLVPNPLLLNSTAEQMEEISESIGKSQFTAESTHLNVGHRSLGHSLSIECKGIDKELNESKNTHLDIPRISSSLGKKPSLTSDSGIHAITP-SVVNFTSLFSNKPFLKLGAVTAPDKHCQVAESLSSSFQSKPLKKRKGRKPRWTKVVARSTCRSPKGLDLERSELFKNVSCSSLSNS-SEPAKFMKTIGASSFVDHDFLKRRLPKLSKSSAPSLALLTDSEKPSHKSFITHKLSSSMCVTSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESENHRSSSDFFESEDQLQDTDDLDDSHRQSVCSMSDLEMEPDKKISKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGLLSGSPASLAVLEQTAQQAAGSALGQILPPLLPSPASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHVHSRQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHISLIPPETSTVLNSLKEKHKHKCKRRSHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPTKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRS-EQPQVSMDSGSSRSVLESLKRYRFGKDTVGDRYKHKEKHRCHMSCPHLSPSKNLINREEQWVSREPSESSSLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHMNLFTSAIGSCRVSNPNSSCRKKLTDSPGLFPVQDTALNRPHRKEPLPSSERAIQSLAGSQSASDKPSQRSSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASMDDSVDSLLQRIVHHDEQESMEKNGDASITTVSAPPSSSPGHSYSKERALGKSDSLLVPAVPNDSCS-NIPLLSEKSASRCSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVSPELNEGED-MSLHLSPDTVTDVIEAVVQSVNLTSEHKKGVKRKNWLLEEQTRKKQKTVPEEEEQENNKSFIETPVEIPSPLETPAEPSEPENTLQPVLALIPREKKAPRPPKKKYQRAGLYSDVYKTIDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHV-----GKYLRQKRIDFQLPYDILWQWKHNQLYKKPDVP--LYKKIRSNVYVDVKP--LSGYEATTCNCKKPDDDTRKGCGDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRMNGLPSHKGSQSSSTHRKSARAKEKRKSKHKLKKRKGHPSEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIHQKQEEVKHTRD-IHSASLYTRWNG--LCRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKEICDGIISYRDSSQQTLAAPLLNLPPKKKNADYYEKISDP--LDLSTIEKQILIGYYKTVEAFDADMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYSARHEASAQIDEIVGET------------ASEADSSETSVSEKESGHEKD---------------------DDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDG----HPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGIK-EQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKRDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAAREVPSPEEPDQERATGDIGDAEKKPEESSQEAQLASTPEERRHSQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPENSFRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR48-1", "uniprot_id": "ASH1L_HUMAN", "id": "Q9NR48-1", "name": "Histone-lysine N-methyltransferase ASH1L", "aln": "MDPRNTAMLGLGSDSEGFSRKSPSAISTGTLVSKREVELEKNTKEEEDLRKRNRERNIEAGKDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHPRKALKSGKMTDEKNEHCPSKRDPSKLYKKADDVAAIECQSEEVIRLHSQGENNPLSKKLSPVHSEMADYINATPSTLLGSRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKLGTGTTAGLVSKDLIRKAGVGSVAGIIHKDLIKKPTISTAVGLVTKDPGKKPVFNAAVGLVNKDSVKKLGTGTTAVFINKNLGKKPGTITTVGLLSKDSGKKLGIGIVPGLVHKESGKKLGLGTVVGLVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAG-LISKDAINLKAEALLPTQEPLKASCSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTSPDFKMGGASDVSTAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSESTHLNVGHRSVGHSISIECKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSESSIHTITP-SVVNFTSLFSNKPFLKLGAVSASDKHCQVAESLSTSLQSKPLKKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLPKLSKSTAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTSLAVLEQTAQQAAGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHKHKCKRRNHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTSAIGSCRVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIATASAPPSSSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSSCSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNRDEEGAALHLSPDTVTDVIEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPESTLQPVLSLIPREKKPPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVVFFVSGKYLRQKRIDFQLPYDILWQWKHNQLYKKPDVP--LYKKIRSNVYVDVKP--LSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNG--ICRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDP--LDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGET------------ASEADSSETSVSEKENGHEKD---------------------DDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDG----HPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVK-EQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPENSFRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW15-1", "uniprot_id": "ASH1_DROME", "id": "Q9VW15-1", "name": "Histone-lysine N-methyltransferase ash1", "aln": "--------------------------------------MSCSQNETAAAKVLETQRAQESGSENEETDSITDQSSQSK-----SIKSATQFSVQRSDTDGLRMRISAIRPTLG--VVATKKPPKSRKMSTQDTESG-----------------------------CSEAKNRAVSKKVK--------------------------------------------------------------------------VKRKKLASSSGISKSDKVSKSKKSQISAFSSDSEDD---------------------------------------------------------LPLKVHQQRAPRVLLSAIIQAAQSAS--KPTLDIGISSSDNELPNLVQAAIKRVESDTEDTTVEGSFRKAAKDKNLPQYQSTLLQ-----------------DFMEKTQMLGQTVNAKLAEEKVAKAKEETLVQTAVPRKRRGRPKKVVP---TVPAPGNSGPAINESADSGVISTTSTTQSTTPSPKMQNENAVPTGSLPIASS-------SKPKIDMAYLDKRMYATERVLYPPPRSKRRQNNKKTACSSSNKEE---------------------LQLDPLWREIDVNKKFRLRSMSVGAASGTGASTTICSKVLAAKSGYVSDYGSVRHQRSSHNHNSGYKSDASCKSRYSTKSCMSRRSRAKSCG---------YRSDCKESGKSGLRMRRKRR-------------ASMLLKSSADDTVEDQDILQLAGLSLGQSSEESNEYIS---KPSLKSLPTTSASKKYGEINRYVTTGQYFGRGGSLSATNPDN--------------FISKMMNQRKETP---------------------------------------------------APSKSSCKIKSRRSS------------------------------------------AASMCSSYVSGVSRMRRRHRRKSFSHNKSLNIDS--------KLLTEIEIITSTFNSRCRIQDDR-----------------------LTGSSGKEKLLADANKLQAT--------------------------------------------LAAPSPAQQLTLNGGGPASTLSKPLKRGLKKRK-------LSEPLVDFAMLSASASGTPNGSGSSNGNTKRRHKKSQSNDSSSPDD----HKLPLKKRHYLLTPGERPPAEVAFANGKLNAEAWAAAAAAAKSTASTKSQAQFNARSVKSALTPKKR---------HLLEQPTSVSGAGSSASNSPLRIVVDNNSISGGKLLDISPSSLCSLKQQRRGGAAKQK------------VSAAKDLVQLQSPAGSYP------------------------PPGVFEPSVELEIQIPLS----------------------KLNESVITKAEVESPLLSA------------------------------------LDIKEDTKKEVGQRVVETLLHKTGGNLLLKRKRKKINRTGFPTVRRKKRKVSVEQQTTAVIDEHEP------------------------EFDPDDEPLQS---------------LRETRSSNNVNVQAAP----------------NPPLDCERVPQAGEARETFVARTNQKAPRLSVVALERLQRPQTPARGRPRGRKP------------------------------KNREQAEAAPQPPPKSEPEIRPAKKRGRQPKQPVLEEPPP------------------TPPPQQKKNKMEPNIRLPDGIDPNTNFSCKIR-----------LKRRKNLEAGTQPKKEKPVQP----------------------------------VTVEEIPPEIPVSQEEIDAEAEAKR---------LDSIPTEHDPLPASESHNPG----------PQDYASCSESSEDKASTTSLRKLS--------KVKKTYLVAGLFSNHYKQSLMPPPAKVNKKPGLEEQVGPAS--LLPPPPYC-----EKYLRRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKIRTNVYAESVRPNLAGFDHPTCNCKNQGE---KSCLDNCLNRMVYTECSPSNCPAGEKCRNQKIQRHAVAPGVERFMTADKGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDTHHYCLHLDGGLVIDGQRMGSDCRFVNHSCEPNCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSLFNPSEGQPCRCNTPQCRGVIGGKSQRVKPLP-------AVEAKPSGEGLSGRNGRQRKQKAKKHAQRQAGKDISS---AVAVAKLQPLSEKEKKLVRQFNTFLVRNFEKIRRCKAKRASDAAATASSPALGTTNGDIPGRRPSTPSSPSLAAQISALCSPRNIKTRGLTQAVHDPELEKMAKMAVVLRDICSAMETLKMSDLLTTVSSKKKKPIKTTLSGKLGSTAATSKVEFRSIQAQVEQGHYKTPQEFDDHMQQLFVEAKQQHGDDEGKEKALQSLKDSYEQQKIASYVQLVEILGDSESLQSFKPKEVLSSEEEPGKIAVKKSPGAKERDSPIVPLKVTPPPLLPIEASPDEDVIRCICGLYKDEGLMIQCSKCMVWQHTECTKADIDADNYQCERCEPREVDREIPLE---EFTEEGHRYYLSLMRGDLQVRQGDAVYVLRDIPIKDESGKVLPTKKHTYETIGAIDYQECDIFRVEHLWKNELGKRFIFGHHFLRPHETFHEPSRRFYPNEVVRVSLYEVVPIELVIGRCWVLDRTTFCKGRPMECNDEDHCYICELRVDKTARFFSKAKAN-HPACTKSYAFRKFPEKIKISKSYAPHDVDPSLLKTRKQKTELDVGAGP------------TTMHKVSGRQEQHQAKMVG----RKPRGISAPADATAVHVVTPVAPNKQMLKKRKSRLENVLITMKLKCLDAQTAQEQPIDLSYLLSGRGARQRKTQQSSSSSTANST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : : :* *:*.:: **: : * :.. .:* :..:*:.. .:. . **:: : .:*. ** **: :..* *:.:...:***:. ::: :.* :** :.* :.*. * .: :.. .. :* *::: . :: *.::: .:. * :*: :.* :..:*: *:.* .. :. .: .*: : :: * : * .: * ::...* *:.* : .:*::::. **. . :* : * .. .. . : ::. .. ... .*:*. :: . . ..*.. *:.: ..*.:.: : : :. * * * : *.* :. :: . : :*:: .*. :: :.:: *. .* : * : : .. * :: *: ::. : .: .* *: * .:.:. :. * * ** *:.. *. . : .: ::*. . :. *:*:*: .*.:*: * :: *.* **: * . *.. . :: ** . * *: .:* ::.:*.* :*** ..: ..:*** ..: .: : :.:*: :*:* :.: * .::* ** . :. :::**.*: * : *:**. . :* :: : * :. **.. * ::. : : .:*:. * *: *.:. .:: *:: ..**. ..*:.: . ... ..*..*..* . *:** : . ** :. .. : . . . : * : * . *. * . ::: .*:.: :.: : * * :: *. ..: .. .* .*: *: . *:: :. :.* *.:* ** ** :: *. . .: **. ** .. : .:**** :.:. .:.:.* : : . : * . *:*.*: : . * : .* :. *:* . .... * *:.** .* : :..** . :: :* :. . **. *: . :. :..*:... : : * : .. .: . .* . *. : :: ..**.*.* :*.* :.:* . . .* : *:. :*. * . : :: .. : * ::: .:*.: *.:* :* :: : :. * . :.:: .* *: :. .::..:* .*.:: . *. : ::.** : . .: * **.* ***:*: ** . ** ** * . *:*.* : ****:..:**:***** * :.:.:* .: ** *:***:***.: *:*:: .*****: .: *.* *:*****:::****..**.**:* **:**** . :*** : :****:*** *: * :*:**:****:*:**::** . * *.:.****:**.*:***. ***.:.**:****:************: *: *:* : : * ******** ** .: * *:*. :***:*******:: *. : *... . *:.::: :* : * ..:..::*.: .. :::*:*::*:::* :.:.*****:***:: : : *:. ** * .. .* : :*:*** :.*.::** *: * .: *: : *::* ::::**..: : : *. : .:. : * *.. :. . : . ::: :*: *: *:*** : ** .* ::* :*:: :* .. : : *:.:* . : : .*: **:*:: :** :..: :*.:. ..:*:* :*******************.******* :* .: *.::* **:*:** ****:*: .::: * *::.*:*.** :****.**::** . :. . :::*. :. *: :: ****:*:***** :** ****::*****.*.****** **:.**.***::*:* *:* * *** *:***** : *:. ***: *:**:*::* * : * :*.***.*** :**:*:. .:.::** * . :. :.: . : * . :.:* . *** :: . : . .:. :. .: :.: : :. :. * * : . ::.**::***. ..*: : : ...: .", "identical_positions": 568, "similar_positions": 856, "identity": "18.83%" }, { "cls_id": "homologset.agr.FB:FBgn0005391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32PY2-1", "uniprot_id": "LIPH_RAT", "id": "Q32PY2-1", "name": "Lipase member H", "aln": "MLRLCFLLSFMCLVKS----------------DTDETCPSFTRLSFHSAVVG---TGLSVRLMLYTQRDQTCAQ---VINSTALGSLNVTKKTTFIIHGFRPTGSPPVWMEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRKVALILKEFIDQMLAKGASLDNIYMIGVSLGAHIAGFVGEMYSGKLGRITGLDPAGPLFNGRPPEDRLDPSDAQFVDVIHSDTDALGYREALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVFLYLASLQNNCSITAYPCDSYRDYRNGKCVSCG-AGHIVSCPSLGYYADNWREYLWDRD---PPMTKAFFDTAETKPYCIYHYFVDIISWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFQKYHQVSLLARFNRDLDKVAEISLLFS-TKSVVGPKYKLRVLRMKLRSLAHPDRPHLCRYDLVLMENVETFFQPILCSKQQM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIV3-1", "uniprot_id": "LIPH_MOUSE", "id": "Q8CIV3-1", "name": "Lipase member H", "aln": "MLRLCFFISFMCLVKS----------------DTDETCPSFTRLSFHSAVVG---TGLSVRLMLYTQRDQTCAQ---IINSTALGSLNVTKKTTFIIHGFRPTGSPPVWIEELVQSLISVQEMNVVVVDWNRGATTVIYPHASSKTRQVASILKEFIDQMLVKGASLDNIYMIGVSLGAHIAGFVGESYEGKLGRVTGLDPAGPLFNGRPPEERLDPSDALFVDVIHSDTDALGYKEALGHIDFYPNGGLDQPGCPKTIFGGIKYFKCDHQMSVYLYLASLQNNCSITAYPCDSYRDYRNGKCVSCG-AGQIVPCPRVGYYADSWKEYLWDRD---PPMTKAFFDTAETKPYCMYHYFVDIVSWNKSVRRGFITIKLRGEDGNITESKIDHEPSAFEKYHQVSLLARFNRDLDKVAEISLLFS-TGSVVGPKYKLRVLQMKLRSLAHPDRPHLCRYDLVLMENVETSFQPILCSQQQM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWY8-1", "uniprot_id": "LIPH_HUMAN", "id": "Q8WWY8-1", "name": "Lipase member H", "aln": "MLRFYLFISLLCLSRS----------------DAEETCPSFTRLSFHSAVVG---TGLNVRLMLYTRKNLTCAQ---TINSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCG-TSQKESCPLLGYYADNWKDHLRGKD---PPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFS-TGSLIGPRYKLRILRMKLRSLAHPERPQLCRYDLVLMENVETVFQPILCPELQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZMG4-1", "uniprot_id": "D3ZMG4_RAT", "id": "D3ZMG4-1", "name": "Lipase member H", "aln": "-MRIYTFLCWICWVRFGYLNFPSKSNGGSKNPENNRTCLEFSKSNAMNSLKDLFYPTVKINLLMYSRNNAKCAEPLFESNNSVNARFNPSKKTIWIIHGYRPLGSTPMWIHKFTKAFLKQEDVNLIVVDWNQGATTFIYGRAVKNTRKVAEILREYIENLLIHGASLDNFHFIGMSLGAHICGFVGKLFQGQLGRITGLDPAGPKFSGKPSNCRLDYTDAKFVDVIHSDSQGFGILEPSGHIDFYPNGGRNQPGCPTSLLSGMDYIKCDHQRAVHLFLEAFETNCNFVSFPCRSYRDYKSGLCVGCG-NLYKDSCPRLGIQANLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALNETMKNGSLSFGLLKDLGVLEYPRLYVKTMPFANLQEVKILAQFVNDIVNISRISMTYYQSTSPFCPTCEYRIKSLVFKSLTHPERPPICKYDFVLKERARIDLQPDECKKQTG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YQT7-1", "uniprot_id": "F6YQT7_MOUSE", "id": "F6YQT7-1", "name": "Lipase member H", "aln": "-MRIYIFLCLICWARFGYLNFQSNTTGVSKDPEKKRTCLEFTKLSAMNSLKDLFCPKVKINLLMYSRGNAKCAEPLFESNNSLNTRFNPAKKTVWIIHGYRPFGSTPVWLSRFTKAFLKQEDVNLIVVDWNQGATTFMYSRAVRNTRRVAEILRETIENLLIHGASLDNFHFIGMSLGAHISGFVGKIFHGQLGRITGLDPAGPQFSRKPSNSRLYYTDAKFVDVIHTDIKSLGIGEPSGHIDFYPNGGKHQPGCPTSIFSGTNFIKCDHQRAIYLFLAAFETSCNFVSFPCRSYKDYKNGLCVDCG-NLYKDSCPRLGNQAKLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALSETMRNGSISFGLLNDLGDLEYSTLYEKSKPFDNLQEVKILVQFVNDIVSISRICLTYFQSTNPYCAACQYKIQSLVLKSLTYPERPPICKYNFVLKEGTRVDLQPDECNTQME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XZB0-1", "uniprot_id": "LIPI_HUMAN", "id": "Q6XZB0-1", "name": "Lipase member I", "aln": "-MRVYIFLCLMCWVRS----------------DNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCD-CFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02844-1", "uniprot_id": "VIT2_DROME", "id": "P02844-1", "name": "Vitellogenin-2", "aln": "-MNPLRTLCVMACLLA--------------------VAMGNPQSGNRSGRRSNSLDNVEQPSNWVNPREVEELPNLKEVTLKKLQEMSLEEGATLLDKLYHLSQFNHVFKPDYTP---EPSQIRGYIVGERGQKIEFNLNTLVEKVKRQQKFGDDEVT-IFIQGLPETNTQVQKATRKLVQAYQQRYNLQPYETTDYSNEEQSQRSSSEEQQTQRRKQNGEQDDTKTGDLIVIQLGNAIEDFEQYATLNIERLG----EIIGNRLVELTNTVNVPQEIIHLIGSGPAAHVAGVAGRQFTRQTGHKLRRITALDPTKIYGKPEERLTGLARGDADFVDAIHTSAYGMGTSQRLANVDFFPNGPSTGVPGADNVVEATMR------ATRYFAESVRPGNERNFPSVAASSYQEYKQNKGYGKRGYMGIATDFDLQGDYILQVNSKSPFGRSTPAQKQTGYHQVHQPWRQSSSNQGSRRQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :. :. . .: . .. . :. . : . . :. : : : : :: :: . . .::. :*. . :.:: : :: .* . : . : . . : . . . : :. *. * : :. .:: *.. . .: * : * .: : : : : . . : ::: . * . . . . . : . . . . : : . . : : .: . .: . : : :* . * : . . .. ", "identical_positions": 10, "similar_positions": 116, "identity": "2.09%" }, { "cls_id": "homologset.agr.FB:FBgn0005411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F2Z3T9-1", "uniprot_id": "F2Z3T9_RAT", "id": "F2Z3T9-1", "name": "Splicing factor U2AF subunit", "aln": "--------------MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR----RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMT--RQARRLYVGNIPFGITEEAMMD----------------FFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSEN----PSVYVPGVVSTVVPDSAHKLFIGGLPNYLN-DDQVKELLTSFG-----PLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDG---VEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26369-1", "uniprot_id": "U2AF2_MOUSE", "id": "P26369-1", "name": "Splicing factor U2AF 65 kDa subunit", "aln": "--------------MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR----RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMT--RQARRLYVGNIPFGITEEAMMD----------------FFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSEN----PSVYVPGVVSTVVPDSAHKLFIGGLPNYLN-DDQVKELLTSFG-----PLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDG---VEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26368-1", "uniprot_id": "U2AF2_HUMAN", "id": "P26368-1", "name": "Splicing factor U2AF 65 kDa subunit", "aln": "--------------MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDR----RNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMT--RQARRLYVGNIPFGITEEAMMD----------------FFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSEN----PSVYVPGVVSTVVPDSAHKLFIGGLPNYLN-DDQVKELLTSFG-----PLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDG---VEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24562-1", "uniprot_id": "U2AF2_DROME", "id": "Q24562-1", "name": "Splicing factor U2AF 50 kDa subunit", "aln": "------------------------MGYDDRERDRERRR-----HRSRSRDR-HRERSRDR----RHH------RNSRR--------------------------KPSLYWDVPPPGFEHITPMQYKAMQASGQIPAS-----VVPD---TPQTAVPVVGSTIT--RQARRLYVGNIPFGVTEEEMME----------------FFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLN-DDQVKELLLSFG-----KLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAAN----TTQSVMLQVPGLSN--VVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRPIEG---VEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKYHRREF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36084-1", "uniprot_id": "MUD2_YEAST", "id": "P36084-1", "name": "Splicing factor MUD2", "aln": "MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHFKRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRSYNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSSDPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVLACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKELFSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKPNDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKYSIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTVLCTYIDEDDFDMMEATQLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..:* . . : :. * . .:.* :. : * . . : .* : : : *: . ** :. *: *:* ..: :. ..: :* * :: : **:*:.. .::* : :** :: .:: : : :*:. :* .. * . : . . . . : :. * :: . . * * .:* :: : : :.* :* : : . *.: : : *. : : : . . . . : . .* . . :.** *:* : * :* *: :* * :: . : . :: : ..*.*:::::*.:: .::* : *.* :* :*.*: .* * *.:. : ", "identical_positions": 52, "similar_positions": 145, "identity": "9.87%" }, { "cls_id": "homologset.agr.FB:FBgn0005427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16656-1", "uniprot_id": "NRF1_HUMAN", "id": "Q16656-1", "name": "Nuclear respiratory factor 1", "aln": "------------------MEEHGVTQTEHMATIEAHAVAQQVQ------------------------QVHVATYTEHS--------MLSADEDSPSSPEDT--------SYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAP-APQEVNS--ELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQ-TQTQATATHS-------------IAHLVPSQTVVQTFSNPDGTVSLIQVG-TGATVATLADASELPTTVTVAQVNYSAVADG-------EVEQNWATLQ----------------------GGE-MTIQTTQAS-EATQAVASLAEAAVAASQEMQQG-----------------------------------ATVTMALN----------SEAAAHAVATLAEAT----------LQG-GGQIVLSGETAAAVG-------ALTGVQDA----------------NGLVQIPVSMYQTVVT--SLAQGNGPVQVAMAPVTTRISDSAVTMDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WU00-1", "uniprot_id": "NRF1_MOUSE", "id": "Q9WU00-1", "name": "Nuclear respiratory factor 1", "aln": "------------------MEEHGVTQTEHMATIEAHAVAQQVQ------------------------QVHVATYTEHS--------MLSADEDSPSSPEDT--------SYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAP-APQEVNS--ELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQ-TQTQATTTHS-------------IAHLVPSQTVVQTFSNPDGTVSLIQVG-TGATVATLADASELPTTVTVAQVNYSAVADG-------EVEQNWATLQ----------------------GGE-MTIQTTQAS-EATQAVASLAEAAVAASQEMQQG-----------------------------------ATVTMALN----------SEAAAHAVATLAEAT----------LQG-GGQIVLSGETAAAVG-------ALTGVQDA----------------NGLVQIPVSMYQTVVT--SLAQGNGPVQVAMAPVTTRISDSAVTMDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90X44-2", "uniprot_id": "NRF1_DANRE", "id": "Q90X44-2", "name": "Nuclear respiratory factor 1", "aln": "------------------MEDHTVHQTEHMTTIEAHAVSQQVG------------------------QVHVATYTEHG--------MLSADEDSPSSPDDD--------AYDDSDILNSTGTDEVTAHLAAAGPVGMAAAAAVATGKKRKRPHIFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFRVFGAAPLENVVRKYKSMILEDLENALAEHAPPGGGELSS--ELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQVTTQVATTATHS-------------IAHLVPSQTVVQTISNPDGTVSLIQVG-TGATVATLADASELPGTVTVAQVNYSTVTDG-------EVEQNWATLQ----------------------GGE-MTIQTTQAS-EATQAVASLAEAAVAASQEMQTG-----------------------------------ATVTMALNRYSLEGALKFGEAAAHAVATLAEAT----------LQG-GGQIVLAGETAAAVG-------ALTGVPDG----------------SGLVQIPVSMYQTVVT--SLAQGNRPVQVAMAPVTTRIDN-TMTLDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24312-1", "uniprot_id": "EWG_DROME", "id": "Q24312-1", "name": "DNA-binding protein Ewg", "aln": "MATTSYRLVVAPAGSQRSSTGNVVVTTTSSGSHSSNGANGGTGGTSAGSSTLGSGLNVTTITATSGGQLQSAGNTSQSNGTTYKIEMLEEDIQSLGSDDDDEDLISSDGSLYEGDLGSMPVNDDVAHQLAAAGPVGVAAAAAIASSKKRKRPHCFETNPSVRKRQQNRLLRKLRAIIYEFTGRVGKQAVVLVATPGKPNTSYKVFGAKPLEDVLRNLKNIVMDELDNALAQQAPPPPQDDPSLFELPGLVIDGIPTPVEKMTQAQLRAFIPLMLKYSTGRGKPGWGRESTRPPWWPKELPWANVRMDARSEDDKQKISWTHALRKIVINCYKYHGREDLLPTFADDE-DKVNALISQSGDEDEDMELSNPPTIHTVTTMTPPTGNSNQPQQVNVVKINSAGTVITTHTAQSNTPAPTIIQSTNNQHVTTTATLPASTKIEICQAPAQNQQHHQHHQTHLPNAVHIQPVAGGQPQTIQLTTASGTATATAVQTTAAAVSAAQAHAHSQSQAHSQSSANQTVTAQQIANAQVCIEPITLSDVDYTTQTVLSQNADGTVSLIQVDPNNPIITLPDGTTAQVQGVATLHQGEGGATIQTVQSLTDVNGHENMTVDLTETQDGQIYITTEDGQGYPVSVSNVISVPVSMYQSVMANVQQIQTNSDGTVCLAPMQVENGDQLETITMSPGMHQMMIQGGPGQEPQLVQVVSLKDATLLSKAMEAINSGNVKSEDTIIMEQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * : .::.. . *:: * *.:. **. * :* .* :* : :.*: . . *:*: :********:*****:*:.******* **:***:*****.******** : *:* ***:**:** :*.***. ::**** ***:*:*: *.:::::*:.***::** : * *** *.*****..*:************ **************:** :* ***:::****** *.*:*::**::***:***.** **** ******* :* *: :. : ::* * *.: * ** *.::::. :*:.::* : *: * .. : ..* . *: ::* *. * **: *** * ** ** :... : ***:*:* . *. .*. . :.: **.:.* ** ** : : :: : *. ** . *. ..::.:******:*:: . * * *.:**: .. .: *: * *:**:*:: ", "identical_positions": 219, "similar_positions": 154, "identity": "29.84%" }, { "cls_id": "homologset.agr.FB:FBgn0005533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08708-1", "uniprot_id": "RS17_HUMAN", "id": "P08708-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63276-1", "uniprot_id": "RS17_MOUSE", "id": "P63276-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04644-1", "uniprot_id": "RS17_RAT", "id": "P04644-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LH50-1", "uniprot_id": "A0ABK0LH50_RAT", "id": "A0ABK0LH50-1", "name": "Small ribosomal subunit protein eS17", "aln": "MSRVRTKTVRKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLTLLDFGRLSHLQVTQPTVGMNFETPLGAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17704-1", "uniprot_id": "RS17_DROME", "id": "P17704-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAAKVIIEKYYTRLTLDFHTNKRICEEVAIIPTKPLRNKIAGYVTHLMGRLRHSQVRGISIKLQEEERERRDNYVPAVSALEQ----DIIEVDADTKEMLKLLDFHNIRGLQLTQPNT-NNFGRRN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14127-1", "uniprot_id": "RS17B_YEAST", "id": "P14127-1", "name": "Small ribosomal subunit protein eS17B", "aln": "MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRN---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02407-1", "uniprot_id": "RS17A_YEAST", "id": "P02407-1", "name": "Small ribosomal subunit protein eS17A", "aln": "MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*******::*::.:**:**.:* **:****:*:*:* * :* ********.**** *:::. *****:*********:*:*** ****: :::** :*.:::. *.: : ... .: ", "identical_positions": 64, "similar_positions": 41, "identity": "46.04%" }, { "cls_id": "homologset.agr.FB:FBgn0005536", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4R1-1", "uniprot_id": "A0A0G2K4R1_RAT", "id": "A0A0G2K4R1-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "MSGEDGPA---------AGPGAAAAAAAARERRQEQLRQWGARAGADPGPGE-------RRAR---TVRFERAAEFLAACAGGDLDEARLMLRAADPGPGSGAATDPAVPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESD---AMEGLLKAEITRRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEAR-HPRTGASALHVAAAKGYIEVMRLLLQAGYDTELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEDVMNLLEELAQKQEDLRNQKEASQGRGQESQVPSNS----KHRRSSVCRLSSREKISLQ-----------------------DLSKERR-------PGGAGGLPIGDEDEGEEALAEHPAVEPRALNGVSSPASSSPKSPVPP--------------------------------EEAPFSRRFGLQKTGSSGALGPSERK------GTEGVLG--LQRSASSSVIEKASTQAREPR------------------------------LARITPTPAQKVPEPFTLSEAAA-PPS-DHSAPPSRT--------------------------------------------------------------------------------------------------------------------------------------EPGSPVKPNVLTASAAPLADSRDRD-------RRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKVAGKV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEPEQPALPSLDPSRRPRVPGVENAEGPAQRAEAPEGQGQGPQAAREHRKAGHERRGPAEGEEAVPAERSPECSTVDGGSTVRRQRSQRDLILESK---------------------------------QQHEEPDGGFRKLYTELRRENERLREALTETTLRLAQLKVELERATQ-RQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMT1-1", "uniprot_id": "PP12C_MOUSE", "id": "Q3UMT1-1", "name": "Protein phosphatase 1 regulatory subunit 12C", "aln": "MSGEDGPA---------AGPGAAAAAAAARERRQEQLRQWGARAGADPGPGE-------RRAR---TVRFERAAEFLAACAGGDLDEARLMLRAADPGPGSGAASDPAVPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESD---AMEGLLKAEITRRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEAR-HPRTGASALHVAAAKGYIEVMRLLLQAGYDTELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEDVMNLLEELAQKQEDLRNQKEGSQGRGQESQVPSSS----KHRRSSVCRLSSREKISLQ-----------------------DLSKERR-------PGGAGGPPIGDEDEGGEASAEHPAVEPRALNGVSSPVSSNPKSPVLP--------------------------------EEAPFSRRFGLQKTGSTGALGPSERR------ATEGVLG--LQRSASSSLLEKASTQAREPR------------------------------LARITPTPAQKVPEPFTLYEAAT-PPSLDHSVPPSRR--------------------------------------------------------------------------------------------------------------------------------------EPGSIVKPNVLTASAAPLADSRD---------RRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKVAGKV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEPEQPALPSLDPSRRPRVPGVENAEGPAQR-EAPEGQGQGPQAAREHRKAGHERRGPAEGEEAGPAERSPECSTVDGGSQVRRQHSQRDLVLESK---------------------------------QEHEEPDGGFRKMYTELRRENERLREALTETTLRLAQLKVELERATQ-RQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZL4-1", "uniprot_id": "PP12C_HUMAN", "id": "Q9BZL4-1", "name": "Protein phosphatase 1 regulatory subunit 12C", "aln": "MSGEDGPA---------AGPG--AAAAAARERRREQLRQWGARAGAEPGPGE-------RRAR---TVRFERAAEFLAACAGGDLDEARLMLRAADPGP--GAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESD---AMEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEAR-HPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEEVLSLLEELARKQEDLRNQKEASQSRGQEPQAPSSS----KHRRSSVCRLSSREKISLQ-----------------------DLSKERR-------PGGAGGPPIQDEDEGEEGPTEPPPAEPRTLNGVSSPPHPSPKSPVQL--------------------------------EEAPFSRRFGLLKTGSSGALGPPERR------TAEGAPGAGLQRSASSSWLEGTSTQAKELR------------------------------LARITPTPSPKLPEPSVLSEVTKPPPCLENSSPPSRIP-------------------------------------------------------------------------------------------------------------------------------------EPESPAKPNVPTASTAPPADSRD---------RRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PESEKPAQ-SLDPSRRPRVPGVENSDSPAQRAEAPDGQGPGPQAAREHRKVGKEWRGPAEGEEAEPADRSQESSTLEGGPSARRQRWQRDLNPEPE---------------------------------PESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELERATQ-RQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDL9-1", "uniprot_id": "A0A8M2BDL9_DANRE", "id": "A0A8M2BDL9-1", "name": "Protein phosphatase 1 regulatory subunit 12C", "aln": "-MGDAAVAKRREQLTRWSGSSTDKEPAVPRSRWRGETSTR-APDGGRPDTNE-------RQKKNRWRVTFEKTAEFLAVCASGDTEEAKAMLREVLLNE-------------EDDVVNCANADGITALHQACIDGSMEMVDFLLSHGANVNQVDSEGWTPLHVAASCGNLEIAEFLLQHGASLCSVNCDGDVPLDIAKDE---DTQMLLQKHILKQGMDLEAAKRAEEEWIMHDARHWLTDGLPANLC-QPRTGATPLHVAAAKGYLEAIKLLCQCGLDVSAKDCDGWTPLHAAAHWGQSDACRLLAEQLCDMEAHSNRGQSPFDVADESVASLLEELSKRQANWRTEQQNSQ----TSNVNPAN----KKRRSSVCRMSSKDKISVQ-----------------------DQSKER---------GVSGELELSDERESSPESS-----------TVSSPESTVPSS--------------------------------------------------------GTTEEK------EVK------------------ANDQDRASR------------------------------TAVVPPTPQKRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPAESPSNTSGD----------GRKYQAPVRDEESEFQRKARSRLMRQSRRSTQGVTLTDLKEAERSIVKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NEPQHVSVQPVSPN-VTVTPAERDTDPERESLEAQTKLG-----VRDRRKGRKERRSTG------VVQLAEENDDMDANEDAQQDNNARDHQLDDS---------------------------------IHS---SLDYRKLYLRVLQENGNLKEKLQETQLQLNESKVQLEKLKQ-NQENGSDRPALLELERYEKKLLQRRAFELEDELKVLVDLRADNQRLKDENAALIRVISKLSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q10728-1", "uniprot_id": "MYPT1_RAT", "id": "Q10728-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----------------------MKMADAKQKRNEQLKRWIGSETDLEPP---------VVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRG-------------------ADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEE---AMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHISDVR-HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRD-KKSPLIESTANM------ENNQPQKTFKNKETLIIE----------PEKNASRIESLEQEKADEEE-EGKKDESSCSSEEDEEDDSESEAETDKTKP-MASVTNAHTASTQAAPAAVTTPTLSSNQG-TPTSPVKKFPTSTTKISPKEEERKDESPASWRLGLRKTGSYGALAEITAS---KEAQKEKDTAG-VIRSASSPRLSSSLDNKEKEKDNKGTR------------------------LAYVAPTIPRRLGSTSDIEEKENRE-SSNLRTSSSYTRRKWEDDLKKN---SSINEGSTYHRSCS----FGRRQD--DLISCSVPSTTSTPTVTSAAG---------LQKS---------FLSSTSTTAKTPPGSSPAGTQS---STSNRLWAEDSTEKEKDSAPTAATILVAPTVVSAAASSTTALTTTTAGTLSSTSEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKDKEEKEKQDKEKQEEKKESEVSREDEYKQKYSRTYDET--YARYRPVSTSSSSTPSSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------LSTLGSSLYASSQLNRPNSLVGITSAYSRGLTKDN-EREGEKKE--EEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQERQSDTEDGSSKRDTQTDSVSRYD--SSSTSSSDRYDSLLGRSASYSYLEERKPYGSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQ-RQERFADRS-LLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBR7-1", "uniprot_id": "MYPT1_MOUSE", "id": "Q9DBR7-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----------------------MKMADAKQKRNEQLKRWIGSETDLEPP---------VVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRG-------------------ADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEE---AMEELLQNEVNRQGVDIEAARKEEERVMLRDARQWLNSGHISDVR-HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADEDILGYLEELQKKQTLLHSEKRD-KKSPLIESTANM------ENNQPQKAFKNKETLIIE----------PEKNASRIESLEHEKADEEE-EGKKDESSCSSEEDEEDDSESEAETDKTKP-MASVSNAHTSSTQAAPAAVTAPTLSSNQG-TPTSPVKKFPISTTKISPKEEERKDESPASWRLGLRKTGSYGALAEISAS---KEAQKEKDTAG-VMRSASSPRLSSSLDNKEKEKDNKGTR------------------------LAYVTPTIPRRLASTSDIEEKENRE-SSSLRTSSSYTRRKWEDDLKKN---SSINEGSTYHRSCS----FGRRQD--DLISCSVPSTTSTPTVTSAAG---------LQRS---------LPSSTSTAAKTPPGSSSAGTQS---STSNRLWAEDSTEKEKDSAPTAVTIPVAPTVVNAAAPSTTTLTTTTAGTVS---EVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESEASREDEYKQKYSRTYDET--YTRYRPVSTSSSSAPSSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------LSTLGSTLYASSQLNRPNSLVGITSAYSRGLAKEN-EREGEKKE--EEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQERQSDTEDGSSKRETQTDSVSRYD--SSSTSSSDRYDSLLGRSASYSYLEDRKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQ-RQERFADRS-QLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14974-1", "uniprot_id": "MYPT1_HUMAN", "id": "O14974-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----------------------MKMADAKQKRNEQLKRWIGSETDLEPP---------VVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRG-------------------ADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEE---AMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVR-HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRD-KKSPLIESTANM------DNNQSQKTFKNKETLIIE----------PEKNASRIESLEQEKVDEEE-EGKKDESSCSSEEDEEDDSESEAETDKTKP-LASVTNANTSSTQAAPVAVTTPTVSSGQA-TPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS---KEGQKEKDTAG-VTRSASSPRLSSSLDNKEKEKDSKGTR------------------------LAYVAPTIPRRLASTSDIEEKENRD-SSSLRTSSSYTRRKWEDDLKKN---SSVNEGSTYHKSCS----FGRRQD--DLISSSVPSTTSTPTVTSAAG---------LQKS---------LLSSTSTTTKITTGSSSAGTQS---STSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAAS-TTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDET--YQRYRPVSTSSSTTPSSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------LSTMSSSLYASSQLNRPNSLVGITSAYSRGITKEN-EREGEKRE--EEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYE--TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQ-RQERFADRS-LLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRG7-1", "uniprot_id": "MYPT1_DANRE", "id": "Q6DRG7-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----------------------MKMADAKQKRNEQLKRWIGSETDLEPP---------LLKKKKTKVKFDDGAVFLAACSSGDTEEVLRMLDRG-------------------ADINYANVDGLTALHQACIDDNVDMVTFLVEHGACINQPDNEGWIPLHAAASCGYLDIAEYLISQGASVGVVNSEGETPLDIAEEE---AMEELLQNEINRQGVDIEAARKEEERIMLRDARQWLNSGQINDVR-HTKSGGTALHVAAAKGYAEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVEHLCDMDVVNKVGQTAFDVADEDILGYLEELQKKQNLLLSEKKDVKKSPLIETTTTG------DNNQSVKPLKSKETLLLE----------PEKTAPRIETLEPEKVDEEEGEGKKDESSCSSEEEEEEDSESENEADKTKSSVPSSVSNSTPTTAPSSITVTSPTTPSNQVTTPTSPTKKVSTPAGKLSPKEEDRKDESPASWRLGLRKTGSYGALAEISTT---KEAQKEKDTAG-VMRSASSPRLSSSLDNKDKEKEKEKTR------------------------LAYVAPTIPRRHVSTSDIDEKENRDSAASLVRSGSYTRRRWEEDLKNSDGTASTNRTSSYQRSTSHTLALGRTSSSRDLPAKSSSASSLEPNNSKAWQPSSYYQSYSIHRSGSFGRRHEDPLSSTSSSTTTTTTTSSVTSPTGHRSLLSRYWAEESAEKEKEKEKESAT--VIPTINTAGTTTTTSTTGTVLGSDG-----RERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRPTRPREDE-----KEEKEKQDKEKQEEKKETET-KEDDYRSRY-RSFEEK--YRTSLASSTTASSTIPSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------SSSSSSSLYSTSSLNRPNSLTGLTSTYSR-STRDT-DRESDRKEKDEDRDGDDKSQPRSIRDRRRPREKRRSTGVSFWTQDSDENEPDHPSDSE-GSTKGEPQSDRLSSNDPLSTSTSSTDRYESLSSRGIG----ESRRPYS-RFEKDDSTDYKKLYEQILAENEKLKAQLRDTELELSDLKLQLEKATQ-RQERFADRS-QLEMEKRERRALERKISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6A6B6-1", "uniprot_id": "A0A8I6A6B6_RAT", "id": "A0A8I6A6B6-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "--------------MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPAERQGAGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARG-------------------ADINTVNVDGLTALHQACIDENLDMVKFLVENRANINQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEP---AMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVR-QARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLRSEKET--RNKLIESDLN--------SKFQSGLFKNKEKMLYE----------EEIPKS-------QETEEEN----KESSSSSSEEEEGEDEVSESETEKEADKKPEVTVNHSNSESKSRIVEQIPTPAQNTF--SASSARRLSG----LFNKAEEPKDESPSSWRLGLRKTGSHNMLSEVTNP---REALRDRGSS--IYRSSSSPRISTLLDDKDKERENR----------------------------SYFSTLVPRRLSGTSDIEEKENRESAVNLVRSGSHTRQLWRDEAKGN-----------------------------ETPQTVAPSTYTSTYLKRTP-----------YKS-----------QADSTAERT-DSGSSSTPLC------------------------VITNRPAPSTANGVPAATVLSSPAADASVE----PREQRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAERQAQEQPGEKLEDSGELEGSTKKQEPSAAPTKEAGEGQQPWGRSLDEEPIYHRLRCPTQPDKLTAPVS-----------------------------------------------------------------------------------------------------------------------------------------------------------------PSASRPSLYTGSQLLHTSRASVPDPE---ATTNTTAAKEMDTSEKEEADLDDQSSNRLSVRERRRLRDRRRGTGINFWTKD--EDETDVSEEVKEAWHERLSRLESGGSNP--TSSDSHSDRASARARREAR---EARLASLTSRVEEDSSRDYKKLYESALTENQKLKTKLQEAQLELADIKAKLEKMAQQKQEKTSDRSSVLEVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG95-1", "uniprot_id": "MYPT2_MOUSE", "id": "Q8BG95-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "--------------MAELEHLGGKRAESARARRAEQLRRWRGSLTEQEPAERQGAGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARG-------------------ADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEP---AMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGRIEDVR-QARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLRSEKET--RNKLIESDLN--------SKFQSGLFKNKEKMLYE----------EEIPKS-------QDTEEEN----KESSSSSSEEEEGEDEVSESETEKEADKKPEATVNHSNSEIKSRIMEQIPAPAQNTF--SASSARRLSS----LFNKAEEPKDESPSSWRLGLRKTGSHNMLSEVANS---REALRDRGSS--IYRSSSSPRISALLDDKDKERENK----------------------------SYFSMLVPRRLSSTSDIEEKENRESAVNLVRSGSHTRQLWRDEAKGS-----------------------------ETPQTIAPSTYTSTYLKRTP-----------YKS-----------QADSTAEKTADSVSSSTPLC------------------------VITNRPAPSTANGVPAATVFSSAGTDPSVE----AREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAERQAQEQPGEKLEDPGGLEGSTKKQEPSAAPTKGAGEG-----RSLEEEPIYHRLRYPTQPDKPTTPVS-----------------------------------------------------------------------------------------------------------------------------------------------------------------PSASRPSLYTGSHLLRTSRASGPDSENSETSTHATAAKEMDTSEKGEADLDDQSSNRLSVRERRRAKDRRRGTGINFWTND--EDETDVSEEVKEALHERLSRLESGGTNP--TSSDSYSDRASARARREAR---EARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKAKLEKMAQQKQEKTSDRSSVLEVEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60237-1", "uniprot_id": "MYPT2_HUMAN", "id": "O60237-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "--------------MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLLARG-------------------ADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEP---AMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVR-QARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKET--RNKLIESDLN--------SKIQSGFFKNKEKMLYE----------EETPKS-------QEMEEEN----KESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQNTF--SASSARRFSSG---LFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANS---REPIRDRGSS--IYRSSSSPRISALLDNKDKERENK----------------------------SYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGN-----------------------------EIPQTIAPSTYVSTYLKRTP-----------HKS-----------QADTTAEKTADNVSSSTPLC------------------------VITNRPLPSTANGVTATPVLSITGTDSSVE----AREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHRLRCPAQPDKPTTPAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------PSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKD--EDETDGSEEVKETWHERLSRLESGGSNP--TTSDSYGDRASARARREAR---EARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMT9-1", "uniprot_id": "A0A8M1RMT9_DANRE", "id": "A0A8M1RMT9-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "-----------------MAATDRSRSEAAKQRRQDQLQRWQGSETDRTGAEAR--SHSVAPGHRRARVRFAQGAVFMAACSAGDREEVAELLRQG-------------------ADINHANIDGLTALHQACIDENAEMVQFLVENGSEVNRGDNEGWTPLHAAASCGFIQITKYLIEHGAHVGAVNSEGELPLDVATED---AMNRLLKAEVKKQGIDVDQARREEERVMLQDAMTVL-AGSGSLVP-HPNTQATALHVAAAKGYIEVLKVLLKCGIDVDSRDSDGWTAFHAAAHWGQEEACSLLAEHMCDMTAVNNVGQTPLDVADENIIDNLEELQKKQNAMRSEKQK-IQTPVIETSPPVSMAPARPRRTSISRMSSREKITLHG---------REKHAPPTLQTLPTEEDEDESTRTASQSKPSSSSSSEEESESESDAESEKAKTREMINNLNNKRNAAPVTSSVTSSGPNQV-------KKTEAG--------RTPVTEAPGSWRTSLRKAGSSVTLGSTGASDAASEALKDPETKLGMTRSASSPRLSSEADNKEPR-------------------------------LARVQPTPSRRLFSISDNSTNSDNT-SSLLSRSSSYTRRLNTQSASDA----------------------------------SNPSLPRSSSYGRKLD-----ES------------------SVTSVNSATSGLSRLNNLV------------------------AQRSAQEEAEKKDPVSNSVTTTTTTTGESE----TKQRRKSYLTPVRDEEAEAQRKARSRHARQSRRSTQGVTLTDLQEAEKTMKTENKGK----------KEDEEKEGKQKKGEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GEVSWRSRIANLQKSDLLGLTHPPGAPRPDRPD--ADSIVADIEER--MRERRRTRARRRGK-----TGESDDNEP---SGEEESSGGREPQTDRH------TSSRADSLLNDCILTRGAD------------------SRDFKKLFEEMSRENRRLQSQLSDTQRTISLTRVELENATK-RQERFTDCTALLEMEKKEKKMLERRAAELEEELKVLGDLRADNQRLKDENGALIRVISKLSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEB2-1", "uniprot_id": "M9NEB2_DROME", "id": "M9NEB2-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "------------------MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTP--------RHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQG-------------------ADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNNYHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSTFNNTHSNTNNTSTTQQQPAAAAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATSTAATAINSPSTTVQTPPIRSQVTAKIAEKSNNGSSSTASVSDAESSKPPPKQSASNMIKNFFKSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNETSSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPAGQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPESSENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATTPAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAGGGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSND------------KTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFAN-----ATTKNSLSELEKRERRAMERKLSELEEELKQLDAYKSDNHRLKEENAALIRVISKLSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : * . *:*.* .** :*. :* :: .* **::******** . ::* **:.. : :*: *.*** ***.:**** :.*:.::: :** : **.:*: . *:* . : : . .:::: ::: ** ::.*: * . :..: .:.********* :.: :* : . :* ****.:***:*** ::. :*.: .* . ** *:**. : ** * .: . . .. :.: . . . : . : : : . : . : ::: :. . : * * *:.. :*: . *. . . .:: :: ** .*: * : : **. : : *:*: *:: ::*: *:*:*:* * ::**:***:**.***********", "identical_positions": 115, "similar_positions": 153, "identity": "8.61%" }, { "cls_id": "homologset.agr.FB:FBgn0005558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88436-1", "uniprot_id": "PAX4_RAT", "id": "O88436-1", "name": "Paired box protein Pax-4", "aln": "-----------------------------------MQQDG----------------LSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQRQLCAEGLCTQDKAPSVSSINRVLRALQEDQ-----------------------------------------------------------------------RLHWTQLRSPA----------------------------------------------------------------------VLAP--------------------------------------------------ALPSPHSNCEAPRGPHPGTS------------------HRNRTIFSPGQAEALEKEFQRGQYPDSVVRGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWETQMP---------------------------------------------------GASQDLMVP-----------------------------------------------------------------------------------------KDSPGIISAQQSPGSVPSAALPVLEQLNP-------------SFCQLCWGAVP-----------------------------------DRCSSDTT------------------------------SQACLQPYWECHS--------LLPVASSSYMEFAWPCLTTH--------------PVHHLIGGPGQAPSTYYLHWP--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32115-1", "uniprot_id": "PAX4_MOUSE", "id": "P32115-1", "name": "Paired box protein Pax-4", "aln": "-----------------------------------MQQDG----------------LSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQ-----------------------------------------------------------------------SLHWTQLRSPA----------------------------------------------------------------------VLAP--------------------------------------------------VLPSPHSNCGAPRGPHPGTS------------------HRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLP---------------------------------------------------GASQDLTVP-----------------------------------------------------------------------------------------KNSPGIISAQQSPGSVPSAALPVLEPLSP-------------SFCQLCCGTAP-----------------------------------GRCSSDTS------------------------------SQAYLQPYWDCQS--------LLPVASSSYVEFAWPCLTTH--------------PVHHLIGGPGQVPSTHCSNWP--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43316-1", "uniprot_id": "PAX4_HUMAN", "id": "O43316-1", "name": "Paired box protein Pax-4", "aln": "-----------------------------------MHQDG----------------ISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLRALQEDQ-----------------------------------------------------------------------GLPCTRLRSPA----------------------------------------------------------------------VLAP--------------------------------------------------AVLTPHSGSETPRGTHPGTG------------------HRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLP---------------------------------------------------GASQGLTVP-----------------------------------------------------------------------------------------RVAPGIISAQQSPGSVPTAALPALEPLGP-------------SCYQLCWATAP-----------------------------------ERCLSDTP------------------------------PKACLKPCWDCGSF-------LLPVIAPSCVDVAWPCLDAS--------------LAHHLIGGAGKATPTHFSHWP--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18381-1", "uniprot_id": "PAX6_DROME", "id": "O18381-1", "name": "Paired box protein Pax-6", "aln": "MRNLPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHPHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSASANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSASGTSAHVAPGKQQFFASCFYSPWV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P26630-1", "uniprot_id": "PAX6_DANRE", "id": "P26630-1", "name": "Paired box protein Pax-6", "aln": "-----------------MPQKEYYNRATWESGVASMMQNS----------------HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMG------------------------------------------------------------------ADGMYEKLRMLN-------------------GQT----GTWGTRP-------------------------GWYPG-------TSVP------------------GQPN--------------------------QDGCQQSDGG---GENTNSISSNGEDSDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQ-------ASNSSSHIPIS---------------------------------SSFSTSVYQP------------------------------------------------------------------IPQPTTPVSFTSG------SMLGRSDTALTNTYSALPPMPSFTMANNLPMQP----------SQTSSYSCMLPTSP---------------------------------SVNGRSYDTY------------------------------TPPHMQAHMNSQS---------MAASGTTSTGLISPGVS----------------VPVQVPGS----EPDMSQYWPRLQ-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *.:*****:**.***** .***:**.** * ******* *:**************.** :.*: *******:**. **.:*:* * * *::*****: :* *.:**:*: *********** * :: :** .* . . ...: :. :**** *: * ::*****:* :*** ..* :** .*** ::************:***: : : * .: * : .: .: : .:*: . : * * * :. . . .. * :. . * : * . :. ", "identical_positions": 132, "similar_positions": 81, "identity": "15.4%" }, { "cls_id": "homologset.agr.FB:FBgn0005561", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LQ26-1", "uniprot_id": "A0ABK0LQ26_RAT", "id": "A0ABK0LQ26-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDMHCKADPFSAMHR------HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIR---------------------------------------TKVQQPF-HPTPDGAGTGVTAPG--HTIVPSTASPPVSS----------------ASNDPVG-SYSINGILGIPRSNGEKRKREEVEVYTDPAHIRGGGGLHLVWTLR---DVSEGSVPNGDSQSGVDSLRKHLRADTFT--------QQQLEAL--------DRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT------------------------------------------------------------------------------------------------------------------------------GRDMASTTLPGYPPHVPPTGQ-----------------------GSYPTSTLAG-----------MVPGSEFSGNPYSHPQYTAYNEAWRFSNP----------ALLM-------------------PPPGAPPLPLLP--LPMTATSYRGDHIKLQADSFGLHIVPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32114-1", "uniprot_id": "PAX2_MOUSE", "id": "P32114-1", "name": "Paired box protein Pax-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDMHCKADPFSAMHR------HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIR---------------------------------------TKVQQPF-HPTPDGAGTGVTAPG--HTIVPSTASPPVSS----------------ASNDPVG-SYSINGILGIPRSNGEKRKREEVEVYTDPAHIRGGGGLHLVWTLR---DVSEGSVPNGDSQSGVDSLRKHLRADTFT--------QQQLEAL--------DRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASANPELGSNVSGTQTYPVVT------------------------------------------------------------------------------------------------------------------------------GRDMTSTTLPGYPPHVPPTGQ-----------------------GSYPTSTLAG-----------MVPGSEFSGNPYSHPQYTAYNEAWRFSNP----------ALLS-------------------SPYYYSAAPRGS--APAAAAYDR--H---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02962-1", "uniprot_id": "PAX2_HUMAN", "id": "Q02962-1", "name": "Paired box protein Pax-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDMHCKADPFSAMHPG-----HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIR---------------------------------------TKVQQPF-HPTPDGAGTGVTAPG--HTIVPSTASPPVSS----------------ASNDPVG-SYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLR---DVSEGSVPNGDSQSGVDSLRKHLRADTFT--------QQQLEAL--------DRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVT------------------------------------------------------------------------------------------------------------------------------GRDMASTTLPGYPPHVPPTGQ-----------------------GSYPTSTLAG-----------MVPGSEFSGNPYSHPQYTAYNEAWRFSNP----------ALLS-------------------SPYYYSAAPRGS--APAAAAAAYDRH---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90268-1", "uniprot_id": "PAX2A_DANRE", "id": "Q90268-1", "name": "Paired box protein Pax-2a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDIHCKADPFSAMHLSHIG--HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR---------------------------------------TKVQQPF-HPSSDGTGTPLSTAG--HTIVPSTASPPVSS----------------ASNDPVG-SYSINGILGIPRSNGEKRKRDDVLWSGNHLDGRKIG--------Y---HGSDGSGPNSDSQGSVESLRKHLRADAFT--------QQQLEAL--------DRVFERPSYPDVFPTSEHIKPEQANEYS-LPALNPGLDEVKPSLSTSVSSDLGSSVS--QSYPVVT------------------------------------------------------------------------------------------------------------------------------GREMASTTLPGYPPHVPPTGQ-----------------------GSYPTSTLAG-----------MVPGSDFSGNPYSHPQYTTYNEAWRFSNP----------ALLS-------------------SPYYYSAASRGS--GPPTAATAYDRH---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02548-1", "uniprot_id": "PAX5_HUMAN", "id": "Q02548-1", "name": "Paired box protein Pax-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLEKNYPTPRTSRTG-----HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR---------------------------------------TKVQQP--------PNQPVPASS--HSIVSTGSVTQVSS----------------VSTDSAGSSYSISGILGITSPSADTNKRK----RDEGIQ--------------------ESPVPNGHSLPGRDFLRKQMRGDLFT--------QQQLEVL--------DRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVT------------------------------------------------------------------------------------------------------------------------------GRDLASTTLPGYPPHVPPAGQ-----------------------GSYSAPTLTG-----------MVPGSEFSGSPYSHPQYSSYNDSWRFPNP----------GLLG-------------------SPYYYSAAARGA--APPAAATAYDRH---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02650-1", "uniprot_id": "PAX5_MOUSE", "id": "Q02650-1", "name": "Paired box protein Pax-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLEKNYPTPRTIRTG-----HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR---------------------------------------TKVQQP--------PNQPVPASS--HSIVSTGSVTQVSS----------------VSTDSAGSSYSISGILGITSPSADTNKRK----RDEGIQ--------------------ESPVPNGHSLPGRDFLRKQMRGDLFT--------QQQLEVL--------DRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLTSPTPADIGSSVPGPQSYPIVT------------------------------------------------------------------------------------------------------------------------------GRDLASTTLPGYPPHVPPAGQ-----------------------GSYSAPTLTG-----------MVPGSEFSGSPYSHPQYSSYNDSWRFPNP----------GLLG-------------------SPYYYSPAARGA--APPAAATAYDRH---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPW6-1", "uniprot_id": "A0ABK0LPW6_RAT", "id": "A0ABK0LPW6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MEIHCKH-DPFASMHR-----HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR---------------------------------------TKVQQP--------PNQPVPASS--HSIVSTGSVTQVSS----------------VSTDSAGSSYSISGILGITSPSADTNKRK----RDEGIQ--------------------ESPVPNGHSLPGRDFLRKQMRGDLFT--------QQQLEVL--------DRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGSLDDMKANLTSPTPADIGSSVPGPQSYPIVT------------------------------------------------------------------------------------------------------------------------------GRDLASTTLPGYPPHVPPAGQ-----------------------GSYSAPTLTG-----------MVPGSEFSGSPYSHPQYSSYNDSWRFPNP----------GLLG-------------------SPYYYSAAARGA--APPAAATAYDRH---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QGF8-1", "uniprot_id": "F1QGF8_DANRE", "id": "F1QGF8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLDQKGPSLRIGRSG-----HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIR---------------------------------------TKVQQP--------PGQSGAVSA--HNLASTVAVTQVSA----------------VTSDAAGSSYSISGILGISSP-ADASKRK----RDDPLQ--------------------DSPLANGHSHSGRDFLRKQMRGELFT--------PQQLE---------------------------------TTDYSAMASLAGGLEEMKNSLANQTGAELGSTVAGPQSYPLVS------------------------------------------------------------------------------------------------------------------------------GRDLASTTLPGYPPHVPPTGQ-----------------------GSYSTPSLTG-----------MVPGGDFSGSPYSHPQYSTYNESWRFANPSLLVFQQEYGSLLGSERAASSGLFPGQTPQPTGSPYYYSAATRGAGTAATATASAYDRH---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51974-1", "uniprot_id": "PAX8_RAT", "id": "P51974-1", "name": "Paired box protein Pax-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MPHNSIRSG-----HGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR---------------------------------------TKVQQPFNLPMDSCVATKSLSPG--HTLIPSSAVTPPES----------------PQSDSLGSTYSINGLLGIAQPGSDNKRKMD-----DSDQ--------------------DSCRLSIDSQSSSSGPRKHLRTDTFG--------QHHLEPL--------ECPFERQHYPEAYASPSHTKGE-QGLYP-LPLLNSTLDDGKATLTPSN-TPLGRNLSTHQTYPVVADPHSPYAIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGA---------------------------------------------------------SVPPFNAFSHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQ-----------------------GSYASSAIAG-----------MVAGSEYSGNAYSHTPYASYSEAWRFPNS----------SLLS-------------------SPYYYSSTTRPS--APPTSATAFDHL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00288-1", "uniprot_id": "PAX8_MOUSE", "id": "Q00288-1", "name": "Paired box protein Pax-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MPHNSIRSG-----HGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR---------------------------------------TKVQQPFNLPMDSCVATKSLSPG--HTLIPSSAVTPPES----------------PQSDSLGSTYSINGLLGIAQPGNDNKRKMD-----DSDQ--------------------DSCRLSIDSQSSSSGPRKHLRTDTFS--------QHHLEAL--------ECPFERQHYPEAYASPSHTKGE-QGLYP-LPLLNSALDDGKATLTSSN-TPLGRNLSTHQTYPVVADPHSPFAIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGA---------------------------------------------------------SVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQ-----------------------GSYASSAIAG-----------MVAGSEYSGNAYSHTPYSSYSEAWRFPNS----------SLLS-------------------SPYYYSSTSRPS--APPTSATAFDHL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06710-1", "uniprot_id": "PAX8_HUMAN", "id": "Q06710-1", "name": "Paired box protein Pax-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MPHNSIRSG-----HGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR---------------------------------------TKVQQPFNLPMDSCVATKSLSPG--HTLIPSSAVTPPES----------------PQSDSLGSTYSINGLLGIAQPGSD-KRKMD-----DSDQ--------------------DSCRLSIDSQSSSSGPRKHLRTDAFS--------QHHLEPL--------ECPFERQHYPEAYASPSHTKGE-QGLYP-LPLLNSTLDDGKATLTPSN-TPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSG---------------------------------------------------------------VPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQ-----------------------GSYASSAIAG-----------MVAGSEYSGNAYGHTPYSSYSEAWRFPNS----------SLLS-------------------SPYYYSSTSRPS--APPTTATAFDHL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16117-1", "uniprot_id": "O16117_DROME", "id": "O16117-1", "name": "", "aln": "MLIMDIQTSTHHIHGLGTHELQHRILHPHILHSTQEETLNTSTGQLEHDSQHLQQHHLTHHQQQDVSPTLHNLQNTRTGDSLSTTINTNQNQHGHQHLSGSNMYTSSQMEDKSKANKYDEYSSRTLSNISDANTTPSANNFITQSQGIEWITAMNDIQNGAEDSHSSQGSISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNP-AYTQYGGAYGSYGYGTG---------SGLINSSYYYESGQTQSPLTHDLRSPLVATRANSLASAASPGSGSACTKSESSDIFLA-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*****.********:*******:***:**********************.*******::.************* **: *.:***:**************** :*.:*.**********:* : * * .. * .: . . : ***.*:*** . .. : .. . . .:: : : : * . * : . . : . :* .: . *:*. :: ..* *. : .:* * *.:.:: :*.*.::: .. .:. * :: : . .*: .* . . . : ", "identical_positions": 128, "similar_positions": 89, "identity": "14.87%" }, { "cls_id": "homologset.agr.FB:FBgn0005564", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63881-1", "uniprot_id": "KCND2_RAT", "id": "Q63881-1", "name": "A-type voltage-gated potassium channel KCND2", "aln": "MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRT-QDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTD--NTGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGH-IKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEP--AFVSKSGSSFETQHHHLLHCLEKTT-------------------NHEFVD-EQVFEESCMEVATVNRPSSHSPSLSSQQ----GVTSTCCSRRHK-KSFRIPNANVSGSHRGSVQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQP-YVTTAIISIPTPPVTTPEGDDRPESPE---------------------YSGGNIVRVSAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0V2-1", "uniprot_id": "KCND2_MOUSE", "id": "Q9Z0V2-1", "name": "A-type voltage-gated potassium channel KCND2", "aln": "MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRT-QDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTD--NTGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGH-IKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEP--AFISKSGSSFETQHHHLLHCLEKTT-------------------NHEFVD-EQVFEESCMEVATVNRPSSHSPSLSSQQ----GVTSTCCSRRHK-KTFRIPNANVSGSHRGSVQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQP-YVTTAIISIPTPPVTTPEGDDRPESPE---------------------YSGGNIVRVSAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZV8-1", "uniprot_id": "KCND2_HUMAN", "id": "Q9NZV8-1", "name": "A-type voltage-gated potassium channel KCND2", "aln": "MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRT-QDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTD--TAGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGH-IKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQ--AFVSKSGSSFETQHHHLLHCLEKTT-------------------NHEFVD-EQVFEESCMEVATVNRPSSHSPSLSSQQ----GVTSTCCSRRHK-KTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQP-YVTTAIISIPTPPVTTPEGDDRPESPE---------------------YSGGNIVRVSAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VSI1-1", "uniprot_id": "Q5VSI1_DANRE", "id": "Q5VSI1-1", "name": "A-type voltage-gated potassium channel KCND1", "aln": "MAAGVAAWLPFARAAAIGWMPVASAPMPPPPR-DKKRG-QDGLIILNVSGTRFQTWRNTLERYPDTLLGSTERDFFFHEETNEYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGIIPEIIGDCCYEEYKDRRRENAERIQDDEEND--NNNDLVMPDLSFRESMWRAFENPHTSTMALVFYYVTGFFIAVSVMANVVETVPCGISLNR-AKELSCGERYALAFFCLDTACVMIFTVEYLLRLIAAPSRYKFVKSVMSIIDVVAIMPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSAGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIMGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQSQRAEKRRAQKKTRLARIRAAKSGGANAYLQYKRNGMLVDMEEEASKEAGQALVCKANPTFETQHHHLLHCLEKTT-------------------NHEFVD-EQTYETSCMEVSLAKPSMSRSSSMSSSP----HGLSSCCTRRNKRKSFNVPNSNMAGGRRGSIQELSTIQIR--ER-PLSNSRSSLNAKFEETVPLNSEEPSYITAAVISMPTPPVTTPEGVDLASSHD---------------------FLQSNIVRVSAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62897-1", "uniprot_id": "KCND3_RAT", "id": "Q62897-1", "name": "A-type voltage-gated potassium channel KCND3", "aln": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR--QDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNESE--NNQE-SMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPG--SKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPE-EEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFID-EQMFEQNCMESSMQNYPSTRSPSLSSHS----GLTTTCCSRRSK-KTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTS-QITTAIISIPTPPALTPEGESRPPPASPGPNTN-------------IPSITSNVVKVSVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0V1-1", "uniprot_id": "KCND3_MOUSE", "id": "Q9Z0V1-1", "name": "A-type voltage-gated potassium channel KCND3", "aln": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR--QDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSE--NNQE-SMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPG--SKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPE-EEQMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFID-EQMFEQNCMESSMQNYPSTRSPSLSSHS----GLTTTCCSRRSK-KTTHLPNSNLPATRLRSMQELSTLHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTS-QITTAIISIPTPPALTPEGESRPPPASPGPNTN-------------IPSITSNVVKVSAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK17-1", "uniprot_id": "KCND3_HUMAN", "id": "Q9UK17-1", "name": "A-type voltage-gated potassium channel KCND3", "aln": "MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR--QDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSE--NNQE-SMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPG--SKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPE-EEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFID-EQMFEQNCMESSMQNYPSTRSPSLSSHP----GLTTTCCSRRSK-KTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTS-QITTAIISIPTPPALTPEGESRPPPASPGPNTN-------------IPSIASNVVKVSAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZYK3-1", "uniprot_id": "D3ZYK3_RAT", "id": "D3ZYK3-1", "name": "A-type voltage-gated potassium channel KCND1", "aln": "MAAGVATWLPFARAAAVGWLPLAQQPLPPAPEVKASR--GDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGPARWPTKEQPCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNG----GLEDSGSGEGQMLCVRSRSAFEQQHHHLLHCLEKTT-------------------CHEFTD-ELTFSEALGAVSLGGR-TSRSTSVSSQPMGPGSLFSSCCSRRGERRAIRLANSTASVSR-GSMQELDTLAGLR--RSPAPQSRSSLNAKPHDSLDLNCESR-DFVAAIISIPTPPANTPD-ESQPSSP-GGGGSGGMANTTLRNSSLATPCLLPETVKISSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03719-1", "uniprot_id": "KCND1_MOUSE", "id": "Q03719-1", "name": "A-type voltage-gated potassium channel KCND1", "aln": "MAAGVATWLPFARAAAVGWLPLAQQPLPPAPEVKASR--GDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGTPRWPSKEQSCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNG----GLEDSGSGDGQMLCVRSRSAFEQQHHHLLHCLEKTT-------------------CHEFTD-ELTFSEALGAVSLGGR-TSRSTSVSSQPMGPGSLFSSCCSRRVNRRAIRLANSTASVSR-GSMQELDTLAGLR--RSPAPQTRSSLNAKPHDSLDLNCDSR-DFVAAIISIPTPPANTPD-ESQPSSPSGGGGSGGTPNTTLRNSSLGTPCLLPETVKISSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSA2-1", "uniprot_id": "KCND1_HUMAN", "id": "Q9NSA2-1", "name": "A-type voltage-gated potassium channel KCND1", "aln": "MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASR--GDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNG----GLEDSGSGEEQALCVRNRSAFEQQHHHLLHCLEKTT-------------------CHEFTD-ELTFSEALGAVSPGGR-TSRSTSVSSQPVGPGSLLSSCCPRRAKRRAIRLANSTASVSR-GSMQELDMLAGLR--RSHAPQSRSSLNAKPHDSLDLNCDSR-DFVAAIISIPTPPANTPD-ESQPSSPGGGGRAG----STLRNSSLGTPCLFPETVKISSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UYF4-1", "uniprot_id": "B0UYF4_DANRE", "id": "B0UYF4-1", "name": "A-type voltage-gated potassium channel KCND1", "aln": "MAAGVATWLPFARAAAVGWLPLAKKTMPKPPIDKKNR--NDEILFVNVSGLRFQTWKNTLDRYPDTLLGSSEKEFFYNEDTQEYFFDRDPEMFRHILNFYRTGRLHYPRQECIQAFDEELAFYGIVPDIIGDCCMEEYRDRKKENQERLAVDTEAEMATDTP-LPPHSTHRERLWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCR-PLKGSKKDLPCGEKYSLAFFCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSVIDVVAIMPYYIGLVMPENEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTKGTNFTSIPASFWYTIVTMTTLGYGDMVPNTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKMRAQQKVRLARIRLAKKGTTNAFLQYKEEG----GFHDR--DHDGALCLKNRSSFEHQHHHLLHCLEKTT-------------------NHEFTD-ELTFSEMCMTESVGYR-TSRSTSISSQ----QGVSTSCCPRRAKRRAIRLANSTVSVSR-GSVQELDTLHVHK--TTIRPQSRSSLNARTED-LKLNCDDR-DFTAAIISIPTPPANTPD-ESLPPSP---AIPG-----ILRNS--RSSSFTHETVKISSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17971-2", "uniprot_id": "KCNAL_DROME", "id": "P17971-2", "name": "Potassium voltage-gated channel protein Shal", "aln": "-MASVAAWLPFARAAAIGWVPIATHPLPPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSE--NGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGR-AGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARWAAQESGIEL--DDNYRDEDIFELQHHHLLRCLEKTT-------------------DREFVELEIPFNGQPKRPGSPSPMASPAHSTNSAA----GLLQSCCGRCCSQRYQACGKYMPAASN----------------------AQNSQNNQPMDGTYLVEASF-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*:*********:**:*:* .:* .* . * * :.:**** **:**: **::********.*::**:. : :*******::** :**:****:** *: **: ::*:****:*::*:::**** *:*:**::** **: * : . *: :*********** ****************::*****:** .**::: .***:*****:*** ***:** ***.* :*::****:******:****** :..*:************************ *******************:***:***************. . ::******:******************.** ***.*.:**************************.***:* :**:*.****** ** . *:: *. . . : :* ******:****** :** : * :. . : : * .* :** * . : : . . ::.* * : : ", "identical_positions": 312, "similar_positions": 114, "identity": "45.68%" }, { "cls_id": "homologset.agr.FB:FBgn0005585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18418-1", "uniprot_id": "CALR_RAT", "id": "P18418-1", "name": "Calreticulin", "aln": "MLLS-------VPLLLGLLGLAAADPAIYFKEQFLDG-------------DAWTNRWVESKHKS------DFGKFVLSSGKFYG-DQEKDKGLQTSQDARFYALSARFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGGLDQKDMHGDS----EYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKD--------IRCKDDEFTHLYTLIVRP-DNTYEVKIDNSQVES-------GSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKP---------------------EHIPDPDAKKPEDWDEEMDGEWEPPVIQNPE-------------------YKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDAN-IYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAE-------DKEDEDDRDEDEDEEDEKEEDEE-----------DATGQAKDEL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14211-1", "uniprot_id": "CALR_MOUSE", "id": "P14211-1", "name": "Calreticulin", "aln": "MLLS-------VPLLLGLLGLAAADPAIYFKEQFLDG-------------DAWTNRWVESKHKS------DFGKFVLSSGKFYG-DLEKDKGLQTSQDARFYALSAKFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDS----EYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKD--------IRCKDDEFTHLYTLIVRP-DNTYEVKIDNSQVES-------GSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKP---------------------EHIPDPDAKKPEDWDEEMDGEWEPPVIQNPE-------------------YKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDAN-IYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAE-------DKEDDDDRDEDEDEEDEKEEDEE-----------ESPGQAKDEL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27797-1", "uniprot_id": "CALR_HUMAN", "id": "P27797-1", "name": "Calreticulin", "aln": "MLLS-------VPLLLGLLGLAVAEPAVYFKEQFLDG-------------DGWTSRWIESKHKS------DFGKFVLSSGKFYG-DEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDS----EYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKD--------IRCKDDEFTHLYTLIVRP-DNTYEVKIDNSQVES-------GSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKP---------------------EHIPDPDAKKPEDWDEEMDGEWEPPVIQNPE-------------------YKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPS-IYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAE-------DKEDDEDKDEDEEDEEDKEEDEEE----------DVPGQAKDEL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29413-1", "uniprot_id": "CALR_DROME", "id": "P29413-1", "name": "Calreticulin", "aln": "MMWC-------KTVIVLLATVGFISAEVYLKENFDN--------------ENWEDTWIYSKHPGK-----EFGKFVLTPGTFYN-DAEADKGIQTSQDARFYAASRKFDGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGES----PYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKD--------IRCKDDVYTHFYTLIVRP-DNTYEVLIDNEKVES-------GNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKP---------------------EHIPDPDATKPEDWDDEMDGEWEPPMIDNPE-------------------FKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDK-LYLRKEICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEVK-NTQAGEKKMKEAQDEVQRKKDEEEAKK------AS-------DKDDEDEDDDDEEKDDESKQDKD--------------QSEHDEL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LT85-1", "uniprot_id": "A0ABK0LT85_RAT", "id": "A0ABK0LT85-1", "name": "Calreticulin", "aln": "MLRLGKNRPGQMPEPKGPGPAGLSRAQVQTDGEDVSGGCRGEEARVGPWMYGWTKRWVQSKHQS------DYGKFRLDSGKFYQ-DKERDKGLQTTEDAKFYALSARFKPFSNENETLVVQFSVKHEQGIDCGGGYVKLFPATLNQEDMHSES----QYYIMFGPDICGFGNNRLQVILYHRGKYHENNKT--------LKCRINKDTHLYTLILRP-NATYEVKIDNEKVTG-------GELEADWDFLPPKKIKDPYARKPRKWDERLQIEDPEDKKPEDWQDS---------------------EFIPDPDAKKPDDWNEAMDGVWEGPLIPNVK-------------------YKGEWKPRIIDNPNYQGEWIHPEIDNPKYRPDPT-ICHYHNISVLGLDLWQVKSGSIFDNFLLTNDEEFAEEVGNMTWGLRKDVEQQWRELYEEMEKQKEAEEAKKKREKQRAKQEDIWGLDEEDEEENEEDAEEEAEERPKQEGSGERASVDQKEAHFEQKDEL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AYG8-1", "uniprot_id": "Q6AYG8_RAT", "id": "Q6AYG8-1", "name": "Calreticulin", "aln": "MVRA-------RVSLWAICVLRVALATVYFQEEFLDG-------------ERWRNRWVQSTNDS------QFGHFRVSSGKFYG-HKEKDKGLQTTQNSRFYAISASFKPFSNKGKTLVIQYTVKHEQKIDCGGGYIKVFPSDLDQKNLNGKS----QYYIMFGPDICGFDIKKVHVILYFKNQYHENKKS--------IRCKVDGFTHLYTLILRP-DLSYEVKVDGQSIES-------GSIEYDWNLTSLKKM-EKTSLESRDWDE------VEGNKAQDWEK-----------------------HFLDAGPSKPSDWNSELDGDW----LQKPP-------------------YEDGLKAEGID----KDVWLHQKMRPAGYLTQYD-LSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFGKATWGETKGPEKEMDAIQAKEEVKKARE-------------------------EDE-DLLMGKFHRHNH------------FSRFHRQGEL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9Q6-1", "uniprot_id": "CALR3_MOUSE", "id": "Q9D9Q6-1", "name": "Calreticulin-3", "aln": "MVSA-------RALLWAICVLRVALATVYFQEEFLDG-------------ERWRNRWVQSTNDS------QFGHFRVSSGKFYG-HKEKDKGLQTTQNSRFYAISASFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPSDLDQKKMNGKS----QYYIMFGPDICGFDIKKVHVILYFKNQYHENKKP--------IRCKVDGFTHLYTLILRP-DLSYEVKVDGQSIES-------GSIEYDWNLTSLRKT-EKTSLDSRDWDQ------VEGSKVQDWEK-----------------------HFLDAGASKPSDWNSELDGDW----LQKPP-------------------YEDGLKAEGID----KDVWLHQKMRPAGYLTQYD-LSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFGKATWGETKGPEKEMDAIQAKEEVKKARE-------------------------EDEEDLLMGKFHRHNH------------FSRFHRQGEL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L12-1", "uniprot_id": "CALR3_HUMAN", "id": "Q96L12-1", "name": "Calreticulin-3", "aln": "MARA-------LVQLWAICMLRVALATVYFQEEFLDG-------------EHWRNRWLQSTNDS------RFGHFRLSSGKFYG-HKEKDKGLQTTQNGRFYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQKNLNGKS----QYYIMFGPDICGFDIKKVHVILHFKNKYHENKKL--------IRCKVDGFTHLYTLILRP-DLSYDVKIDGQSIES-------GSIEYDWNLTSLKK--ETSPAESKDWEQ------TKDNKAQDWEK-----------------------HFLDASTSKQSDWNGDLDGDWPAPMLQKPP-------------------YQDGLKPEGIH----KDVWLHRKMKNTDYLTQYD-LSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREMDAIQAKEEMKKARE-------------------------EEEEELLSGKINRHEHY-----------FNQFHRRNEL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27825-1", "uniprot_id": "CALX_YEAST", "id": "P27825-1", "name": "Calnexin homolog", "aln": "MKFS-------AYLWWLFLNLALVKGTSLLSNVTLAEDSFWEHFQAYTNTKHLNQEWITSEAVNNEGSKIYGAQWRLSQGRLQGSAWDKGIAVRTGNAAAMIGHLLETPINVSETDTLVVQYEIKLDNSLTCGGAFIKLMSGFMNVEALKHYAPDTEGVELVFGPDYCAPEINGVQFAINKVDKITHESKLRYLQEMPLSKLTDTSQSHLYTLIIDESAQSFQILIDGKTVMVREHIEDKKKVNFEPPITPPLMIPDVSVAKPHDWDDRIRIPDPEAVKLSDRDERDPLMIPHPDGTEPPEWNSSIPEYILDPNAQKPSWWKELEHGEWIPPMIKNPLCTAERGCGQQIPGLINNAKYKGPGELNEIINPNYMGEWHPPEIENPLYYEEQHPLRIENVISGVILEFWSGSPNMLISNIYVGKNVTEAQIIGNKTWLMRDRAFRGSDGPTERKFMNSRLGNLQTTFHNERES---------PNPFDRIIDRILEQPLKFVLT----------AAVVLLTTSVLCCVVFT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *: * . .:: : * : : . .::* : . : . .: ..**:*: :* :: : ***.::*:: :: :: : ::**** *. : ::. : .: .* : :*:****: :::: :*.. : .:: : : . : ....*:: * .* :. .: *... * . *. .* * : : ::. : . : . * :: . * : : . : : :::*. .. ::.*. : .: * . . . : . . : : . . * ", "identical_positions": 39, "similar_positions": 125, "identity": "7.39%" }, { "cls_id": "homologset.agr.FB:FBgn0005586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63012-1", "uniprot_id": "RAB3A_RAT", "id": "P63012-1", "name": "Ras-related protein Rab-3A", "aln": "--------MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQA-PPHQDCAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63011-1", "uniprot_id": "RAB3A_MOUSE", "id": "P63011-1", "name": "Ras-related protein Rab-3A", "aln": "--------MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQA-PPHQDCAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20336-1", "uniprot_id": "RAB3A_HUMAN", "id": "P20336-1", "name": "Ras-related protein Rab-3A", "aln": "--------MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLSDQQV-PPHQDCAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62823-1", "uniprot_id": "RAB3C_MOUSE", "id": "P62823-1", "name": "Ras-related protein Rab-3C", "aln": "MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLET-DPAITAAKQSTRLKETPP-PPQPNCGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62824-1", "uniprot_id": "RAB3C_RAT", "id": "P62824-1", "name": "Ras-related protein Rab-3C", "aln": "MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLET-DPAITAAKQSTRLKETPP-PPQPNCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96E17-1", "uniprot_id": "RAB3C_HUMAN", "id": "Q96E17-1", "name": "Ras-related protein Rab-3C", "aln": "MRHEAPMQMASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLET-DPAITAAKQNTRLKETPP-PPQPNCAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35276-1", "uniprot_id": "RAB3D_MOUSE", "id": "P35276-1", "name": "Ras-related protein Rab-3D", "aln": "--------MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPGSNGK-GPALGDTPP-PQPSSCSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63942-1", "uniprot_id": "RAB3D_RAT", "id": "Q63942-1", "name": "GTP-binding protein Rab-3D", "aln": "--------MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVSAEDGQRLAGDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPGSNGK-GPALGDTPP-PQPSSCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95716-1", "uniprot_id": "RAB3D_HUMAN", "id": "O95716-1", "name": "Ras-related protein Rab-3D", "aln": "--------MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSSSSGSNGK-GPAVGDAPA-PQPSSCSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZT8-1", "uniprot_id": "RAB3B_MOUSE", "id": "Q9CZT8-1", "name": "Ras-related protein Rab-3B", "aln": "--------MASVTDGKTGIKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSMDT-DPSVLGASKTTRLSDTPP-LLQQNCSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63941-1", "uniprot_id": "RAB3B_RAT", "id": "Q63941-1", "name": "Ras-related protein Rab-3B", "aln": "--------MASVTDGNTGIRDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVIPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSMDT-DPSVLGASKTTRLSDTPP-LLQQNCSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20337-1", "uniprot_id": "RAB3B_HUMAN", "id": "P20337-1", "name": "Ras-related protein Rab-3B", "aln": "--------MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDT-DPSMLGSSKNTRLSDTPP-LLQQNCSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25228-1", "uniprot_id": "RAB3_DROME", "id": "P25228-1", "name": "Ras-related protein Rab-3", "aln": "--------MASGGD-PKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q1L986-1", "uniprot_id": "Q1L986_DANRE", "id": "Q1L986-1", "name": "small monomeric GTPase", "aln": "--------MAKADQ-RFGQRDGSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFSSSFVSTVGIDFKVKTVYRNDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESYNAVQDWATQIKTYSWDNAQVILVGNKCDMDEERVVPFEKGKHLADQLGFEYYEASAKENINVRQVFERLVDIICVKMSERVDVEPPMVTG-AKTTRLTDKPPQLPQNCC--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. : ::.:*********:*:******************:*:.:*************:::::**:***************************:****::*::*: :**** *************:*.*****::::**:. * *: *. .**.:::*:***:*:.*: .****** ** **.: :: . : : * ", "identical_positions": 126, "similar_positions": 53, "identity": "55.02%" }, { "cls_id": "homologset.agr.FB:FBgn0005590", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7P9-1", "uniprot_id": "D4A7P9_RAT", "id": "D4A7P9-1", "name": "", "aln": "---------------MHWTVFLLRGIVGF--LWSSWVQVGYAKGGLG-DNHVHSSFIYRRLRNHERR---EIQREILSILGLPHRPRPFSP---GKQASSAPLFMLDLYNAMASEENPEESEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRIPLTTQSPPLASLHDTNFLNDADMVMS-FVNLVERDKD-------FSHQRRHYKEFR---FDLTQIPHGEAVTAAEFRIYKDKS-NHRFENETIKISIYQIIKEYTNRDADLFLLDTRKAQ----ALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGD-GRSINVKSAGLVGRHGP-----QSKQPFMVAFFKASEVLLRSVRAAS-KRKNQNRNKSSSHQDPSRIPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEG--------------------------------YAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKP-------------CCAPTKLNAISVLYFDDSSNVILKKYR-----NMVVRSCGCH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49003-1", "uniprot_id": "BMP5_MOUSE", "id": "P49003-1", "name": "Bone morphogenetic protein 5", "aln": "---------------MHWTVFLLRGIVGF--LWSGWVQVGYAKGGLG-DNHVHSSFIYRRLRNHERR---EIQREILSILGLPHRPRPFSP---GKQASSAPLFMLDLYNAMASEDNPEE--YLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRTPLTTQSPPLASLHDTNFLNDADMVMS-FVNLVERDKD-------FSHQRRHYKEFR---FDLTQIPHGEAVTAAEFRIYKDKG-NHRFENETIKISIYQIIKEYTNRDADLFLLDTRKTQ----ALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGD-GRSINVKSAGLVGRHGP-----QSKQPFMVAFFKASEVLLRSVRAAS-KRKNQNRNKSNSHQDPSRMPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEG--------------------------------YAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKP-------------CCAPTKLNAISVLYFDDSSNVILKKYR-----NMVVRSCGCH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22003-1", "uniprot_id": "BMP5_HUMAN", "id": "P22003-1", "name": "Bone morphogenetic protein 5", "aln": "---------------MHLTVFLLKGIVGF--LWSCWVLVGYAKGGLG-DNHVHSSFIYRRLRNHERR---EIQREILSILGLPHRPRPFSP---GKQASSAPLFMLDLYNAMTNEENPEESEYSVRASLAEETRGARKGYPASPNGYPRRIQLSRTTPLTTQSPPLASLHDTNFLNDADMVMS-FVNLVERDKD-------FSHQRRHYKEFR---FDLTQIPHGEAVTAAEFRIYKDRS-NNRFENETIKISIYQIIKEYTNRDADLFLLDTRKAQ----ALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGD-GRSINVKSAGLVGRQGP-----QSKQPFMVAFFKASEVLLRSVRAAN-KRKNQNRNKSSSHQDSSRMSSVGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEG--------------------------------YAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKP-------------CCAPTKLNAISVLYFDDSSNVILKKYR-----NMVVRSCGCH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V6W8-1", "uniprot_id": "G3V6W8_RAT", "id": "G3V6W8-1", "name": "Bone morphogenetic protein 7", "aln": "---------------MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERR---EMQREILSILGLPHRPRPHLQ---GKHN-SAPMFMLDLYNAMAVE---------------------ESG-PDGQG-----FSYPYKAVFSTQGPPLASLQDSHFLTDADMVMS-FVNLVEHDKE-------FFHPRYHHREFR---FDLSKIPEGEAVTAAEFRIYKDYI-RERFDNETFQITVYQVLQEHSGRESDLFLLDSRTIW----ASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLD-GQSINPKLAGLIGRHGP-----QNKQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTPKNQEALRMASVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEG--------------------------------YAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKP-------------CCAPTQLNAISVLYFDDSSNVILKKYR-----NMVVRACGCH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23359-1", "uniprot_id": "BMP7_MOUSE", "id": "P23359-1", "name": "Bone morphogenetic protein 7", "aln": "---------------MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERR---EMQREILSILGLPHRPRPHLQ---GKHN-SAPMFMLDLYNAMAVE---------------------ESG-PDGQG-----FSYPYKAVFSTQGPPLASLQDSHFLTDADMVMS-FVNLVEHDKE-------FFHPRYHHREFR---FDLSKIPEGEAVTAAEFRIYKDYI-RERFDNETFQITVYQVLQEHSGRESDLFLLDSRTIW----ASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLD-GQSINPKLAGLIGRHGP-----QNKQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTPKNQEALRMASVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEG--------------------------------YAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKP-------------CCAPTQLNAISVLYFDDSSNVILKKYR-----NMVVRACGCH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18075-1", "uniprot_id": "BMP7_HUMAN", "id": "P18075-1", "name": "Bone morphogenetic protein 7", "aln": "---------------MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERR---EMQREILSILGLPHRPRPHLQ---GKHN-SAPMFMLDLYNAMAVE---------------------EGGGPGGQG-----FSYPYKAVFSTQGPPLASLQDSHFLTDADMVMS-FVNLVEHDKE-------FFHPRYHHREFR---FDLSKIPEGEAVTAAEFRIYKDYI-RERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLW----ASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLD-GQSINPKLAGLIGRHGP-----QNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEG--------------------------------YAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKP-------------CCAPTQLNAISVLYFDDSSNVILKKYR-----NMVVRACGCH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34820-1", "uniprot_id": "BMP8B_HUMAN", "id": "P34820-1", "name": "Bone morphogenetic protein 8B", "aln": "----------------------MTALPGP--LWLLGLAL-CALGGGGPGLRPPPGCPQRRLGARERR---DVQREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGD-------------------------DDEDG-----------------APAERRLGR------ADLVMS-FVNMVERDRA-------LGHQEPHWKEFR---FDLTQIPAGEAVTAAEFRIYKVPS-IHLLN-RTLHVSMFQVVQEQSNRESDLFFLDLQTLR----AGDEGWLVLDVTAASDCWLLKRHKDLGLRLYVETED-GHSVDPGLAGLLGQRAP-----RSQQPFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQG--------------------------------YSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAVPKA-------------CCAPTKLSATSVLYYDSSNNVILRKHR-----NMVVKACGCH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7Z5Y6-1", "uniprot_id": "BMP8A_HUMAN", "id": "Q7Z5Y6-1", "name": "Bone morphogenetic protein 8A", "aln": "----------------------MAARPGP--LWLLGLTL-CALGGGGPGLRPPPGCPQRRLGARERR---DVQREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGD-------------------------DDEDG-----------------APAEQRLGR------ADLVMS-FVNMVERDRA-------LGHQEPHWKEFR---FDLTQIPAGEAVTAAEFRIYKVPS-IHLLN-RTLHVSMFQVVQEQSNRESDLFFLDLQTLR----AGDEGWLVLDVTAASDCWLLKRHKDLGLRLYVETED-GHSVDPGLAGLLGQRAP-----RSQQPFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVRGSHGRQVCRRHELYVSFQDLGWLDWVIAPQG--------------------------------YSAYYCEGECSFPLDSCMNATNHAILQSLVHLMKPNAVPKA-------------CCAPTKLSATSVLYYDSSNNVILRKHR-----NMVVKACGCH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34821-1", "uniprot_id": "BMP8A_MOUSE", "id": "P34821-1", "name": "Bone morphogenetic protein 8A", "aln": "----------------------MAMRPGP--LWLLGLAL-CALGGG-HGPRPPHTCPQRRLGARERR---DMQREILAVLGLPGRPRPRAQPAAARQPASAPLFMLDLYHAMT---------------------------DDDDG-----------------GPPQAHLGR------ADLVMS-FVNMVERDRT-------LGYQEPHWKEFH---FDLTQIPAGEAVTAAEFRIYKEPS-THPLN-TTLHISMFEVVQEHSNRESDLFFLDLQTLR----SGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETAD-GHSMDPGLAGLLGRQAP-----RSRQPFMVTFFRASQSPVRAPRAARPLKRRQPKKTNELPHPNKLPGIFDDGHGSRGREVCRRHELYVSFRDLGWLDWVIAPQG--------------------------------YSAYYCEGECAFPLDSCMNATNHAILQSLVHLMKPDVVPKA-------------CCAPTKLSATSVLYYDSSNNVILRKHR-----NMVVKACGCH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55105-1", "uniprot_id": "BMP8B_MOUSE", "id": "P55105-1", "name": "Bone morphogenetic protein 8B", "aln": "----------------------MAARPGL--LWLLGLAL-CVLGGG-HLSHPPHVFPQRRLGVREPR---DMQREIREVLGLPGRPRSRAPVGAAQQPASAPLFMLDLYRAMT---------------------------DDSGG-----------------GTPQPHLDR------ADLIMS-FVNIVERDRT-------LGYQEPHWKEFH---FDLTQIPAGEAVTAAEFRIYKEPS-THPLN-TTLHISMFEVVQEHSNRESDLFFLDLQTLR----SGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETED-GHSIDPGLAGLLGRQAP-----RSRQPFMVGFFRANQSPVRAPRTARPLKKKQLNQINQLPHSNKHLGILDDGHGSHGREVCRRHELYVSFRDLGWLDSVIAPQG--------------------------------YSAYYCAGECIYPLNSCMNSTNHATMQALVHLMKPDIIPKV-------------CCVPTELSAISLLYYDRNNNVILRRER-----NMVVQACGCH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LE75-1", "uniprot_id": "A0ABK0LE75_RAT", "id": "A0ABK0LE75-1", "name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase", "aln": "MTQRRGNVRCSHKVHLAFPSLSRSWEPGGSRTMAALRLLAWAFSRRVSAHRPRPTLPHHLIRHYPTTRCGKVKFYTDPVKAVEGIKDGASVMLGGFGLCGIPENLIGALKTKGVKDLKIIS---------------SNVGVDDFGLGILLASKQVRRVVCSYLGENKLCEQLYLAGKLELEMTPQGTLAERIRAGGTGVPAFYTPTGYGTQVQEGGVPIRYSPEGHLITLSQPREVREFEGQHHLLERAIRADFALIKGWKADRSGNVIFRGSARNFNVPMCKAADISVVEVEEIVDVGTFAPEDIHIPNIYVKRVIKGPRFEKRIERLTTRDSPPAPGSKDQDPKRTRIIKRAALEFKDGMYAN-LGIGIPVLASNYISPKMTVYLHSENGILGLGPFPLKKEVDPDIINAGKQTVTVIPGGCFFASDDSFAMIRGGHIQLTMLGAMQVSKYGDLANWMVPGKKVKGMGGAMDLVSSKKTKVVVTMEHCTKTKQPKILEKCTMPLTGKSCVDLIITEKAVFEVDRSKGLKLVELWEGSSLDEVKATTGCSFKVCPNLKPMQQIKSDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LL73-1", "uniprot_id": "A0ABK0LL73_RAT", "id": "A0ABK0LL73-1", "name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase", "aln": "MTQRRGNVRCSHKGHLAFPSLSRSWEPRGSRTMAALRLLAWAFSRRVSAHRPQPTLPHHLIRHYPTTRCGKVKFYTDPVKAVEGIKDGASVMLGGFGLCGIPENLIGALKTKGVKDLKIIS---------------SNVGVDDFGLGILLASKQVRRVVCSYLGENKLCEQLYLAGKLELEMTPQGTLAERIRAGGTGVPAFYTPTGYGTQVQEGGVPIRYSPEGHLITLSQPREVREFEGQHHLLERAIRADFALIKGWKADRSGNVIFRGSARNFNVPMCKAADISVVEVEEIVDVGTFAPEDIHIPNIYVKRVIKGPRFEKRIERLTTRDSPPAPGSKDQDPKRTRIIKRAALEFKDGMYAN-LGIGIPVLASNYISPKMTVYLHSENGILGLGPFPLKKEVDPDIINAGKQTVTVIPGGCFFASDDSFAMIRGGHIQLTMLGAMQVSKYGDLANWMVPGKKVKGMGGAMDLVSSKKTKVVVTMEHCTKTKQPKILEKCTMPLTGKSCVDLIITEKAVFEVDRSKGLKLVELWEGSSLDEVKATTGCSFKVCPNLKPMQQIKSDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54631-1", "uniprot_id": "SCW_DROME", "id": "P54631-1", "name": "Protein screw", "aln": "---------------------------------MLNVFFLTSLFYAASATTYVTTNNHIEMPIYQKRP-LSEQMEMIDILDLGDRPRRQAEP---NLHNSASKFLLEVYNEISED-------------------------QEPKE--------------VLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSR------LKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPS----LVDRRANFTVSVYRKLDNRQDFSYRILGSVNTT----SSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGD--SQLSTFAAGLVTPQASR----TSLEPFIVGYFNGPE-LLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPP---QSCERLNFTVDFKELHMHNWVIAPKK--------------------------------FEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP-HLPKP-------------CCVPTVLGAITILRYLNEDIIDLTKYQ-----KAVAKECGCH-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : : . . :: . : . : . * . :. : * : : . . :. . : . . . .:: .: . .. * .. . :* . :. . : :. .: : : * : * :. *: .. : :: : : .*. : ::: .. : * . . * ** ", "identical_positions": 12, "similar_positions": 75, "identity": "2.11%" }, { "cls_id": "homologset.agr.FB:FBgn0005593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUE9-1", "uniprot_id": "F1LUE9_RAT", "id": "F1LUE9-1", "name": "Large ribosomal subunit protein uL30", "aln": "----------------------------------------------------LEGARGTLKK----------KKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAF-------------VRNVLQLLRLRQIFNGTFVKLNKASVNMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDISLIARSLG-KFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L1D0-1", "uniprot_id": "A0ABK0L1D0_RAT", "id": "A0ABK0L1D0-1", "name": "Large ribosomal subunit protein uL30", "aln": "MLTWEMHADWWAGTHNAAHYFRTCWATVLNVPWPSSLFPAGTMEAVPEKKKKVAAAPGTLKK----------KKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASVNMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLVARSLG-KFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14148-1", "uniprot_id": "RL7_MOUSE", "id": "P14148-1", "name": "Large ribosomal subunit protein uL30", "aln": "------------------------------------------MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLG-KFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18124-1", "uniprot_id": "RL7_HUMAN", "id": "P18124-1", "name": "Large ribosomal subunit protein uL30", "aln": "----------------------------------------------------MEGVE--EKK----------KEVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLG-KYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGM--KKKTTHFVEGGDAGNREDQINRLIRRMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32100-1", "uniprot_id": "RL7_DROME", "id": "P32100-1", "name": "Large ribosomal subunit protein uL30", "aln": "-----------------------------------------------------MPAPVVKKP--------AAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGW--RKKANHYVNGGDFGNREDQINRLLRKMV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05737-1", "uniprot_id": "RL7A_YEAST", "id": "P05737-1", "name": "Large ribosomal subunit protein uL30A", "aln": "-----------------------------------------------------MAAEKILTP-----------------ESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLG-KYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSMN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12213-1", "uniprot_id": "RL7B_YEAST", "id": "Q12213-1", "name": "Large ribosomal subunit protein uL30B", "aln": "-----------------------------------------------------MSTEKILTP-----------------ESQLKKTKAQQKTAEQIAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLG-KYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKAMN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *: * : . .: :: : *::** : *: * *: ..:** *: **.* *:****:** :* .*.*:*:.**::::*:: ***:::***. .::.:*:****: * *::*:.::* :: .* . * .::**:*** *** .** *.********..* ** :* .*:::**. ****: **:*:: * ", "identical_positions": 79, "similar_positions": 73, "identity": "25.08%" }, { "cls_id": "homologset.agr.FB:FBgn0005596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8C6-1", "uniprot_id": "D4A8C6_RAT", "id": "D4A8C6-1", "name": "", "aln": "---MSEPHRVQFTSLP----------------------GSLNPALLKKSRKEEVG------------------------------------------------------------GTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNTRGKVKGLHPGDKKK--DVLDPFNDEEKERHKVEALARKFEEKYGGK--KRRKD-RIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESE-DDFIKEKKKKSPKKRK--LKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASK-EKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSS-----------VEAQGLRELEGTS-DPLLSLFGSTSDNDLLQAAT-AMDSLTDLDLEQLLSESPEGSPFRDMD--DGSDSLGVGLDQEFRQPS-SFPEGLPTPLEKRVKELAQAARAAEGDSKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKVKTKESSVKPDK--------KVSIPSGQHGGPTTLLSEHQGGGLNIGANSREHPSQATCGLTDPVPVTLEDSLDEDLVRNPASSVDAVSKELAVLNSRAAN---SSEFTLPAPSKAP---TEKVAGVLCTEEKRNFTKPSSSAPPPTNALQSPLN------------------FLAEQALALGQSSQEKKPEGSGYKELSCQAPLSKGMP-ELHQSKAKHHSLQRTSHGPQAAAPVPGP----QVKVFHAGTQQQKSFTPPSPFVNKLQG---PKATSPQCHRSFLQLVKTAAK-------------GQSFHATMPASSGSSPASSSSS---------------HKTTASNSTTISHPAKLHPASSVGPSYKNNPFAG---------SISKHGAASS----------STSSGGGAQVQSSVSGTLLPGVQPPSAG-----------QPASRTAPSSAVKKTPVTQKLTLVAPPG-------------------------GPN-----GDSGGGTQGVAKLLTS-SLKPAAVSSVTSSTSLPKGTGGAVLLSNNSSLSLLSSSYKSNTPKLP-GTMNSNSLGIIT--PFPLHVLSFSADSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSS-PPHTAPLPHAAVSTHVPQSLPDTSQLHGKGPVVPRKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4G0F8-1", "uniprot_id": "UBN1_MOUSE", "id": "Q4G0F8-1", "name": "Ubinuclein-1", "aln": "---MSEPHRVQFTSVP----------------------GSLNPAFLKKSRKEEVG------------------------------------------------------------GTEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLHPGDKKK--DVLDPFNDEEKERHKVEALARKFEEKYGGK--KRRKD-RIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESE-DDFIKEKKKKSPKKRK--LKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASK-EKKKKKYSGSLSVREMLKKFQKEKEAQKKREEEHKPVAVSS-----------IEAQGLRELEGTS-DPLLSLFGSTSDNDLLQAAT-AMDSLTDLDLEQLLSESPEGSPFRDMD--DGSDSLGVGLDQEFRQPS-SFPEGLPIPLEKRVKELAQAARAAEGESKQKFFTQDINGILLDIEVQTRELTSQIRSGVFAYLASFLPCSKDALVKRARKLHLYEQGGRLKEPLQKLKDAIGRAMPEQVAKYQDECQAHTQAKVAKMLEEEKDKEQRERICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESRDLERNSKAQAWEDCVKAFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSLLAKKKVIAPSKIKMKESSVKLDK--------KVSVPSGQHGGPTTLLSEHQGGGLNTGANSREHPSQATCGLTDSVSVTLEDSLDEDLVRNPASSVDAVSKELATLNSRAAN---SSEFTLPTPSKAP---TEKVGGVLCTEEKRNFAKPSSSAPPPTNALQSPLN------------------FLAEQALALGQSSQEKKPEGSGFKELSCQGPLSKGVP-ELHPSKAKHHNLPRTSHGPQAAAPVPGP----QVKVFHAGTQQQKSFTPPSPFVNKLQG---PKATSPQCHRSLLQLVKTAAK-------------GQAFHATMPASSGSSPASSSSA---------------HKTTASNSTTISHPAKLHPTSSVGPSYKNNPFAG---------SVSKHGASSS----------SPSPGGGAQVQSSVSGASLPGVQSPSAG-----------QSASRAAPSSAVKKTPVTQKLTLVAPPG-------------------------GPN-----GDSGGGTQGVAKLLTS-SLKPAAVSSVTSSTSLPKGTGGAVLLSNTSSLSLLSSSYKSNNPKLP-GAMNSNSLGIIT--QFPLHVLSFNADSSAKAGVSKDAIVTGPAPGTFHHGLSHSLLAGLHSS-PPHTAPLPHAAVSTHVPQSLPDASQLHGKGPVVPRKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPG3-1", "uniprot_id": "UBN1_HUMAN", "id": "Q9NPG3-1", "name": "Ubinuclein-1", "aln": "---MSEPHRVQFTSLP----------------------GSLNPAFLKKSRKEEAG------------------------------------------------------------AGEQHQDCEPAAAAVRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLQPGDKKK--DLSDPFNDEEKERHKVEALARKFEEKYGGK--KRRKD-RIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGFYINSGTLQFRQASESE-DDFIKEKKKKSPKKRK--LKEGGEKIKKKKKDDTYDKEKKSKKSKFSKAGFTALNASK-EKKKKKYSGALSVKEMLKKFQKEKEAQKKREEEHKPVAVPS-----------AEAQGLRELEGAS-DPLLSLFGSTSDNDLLQAAT-AMDSLTDLDLEHLLSESPEGSPFRDMD--DGSDSLGVGLDQEFRQPS-SLPEGLPAPLEKRVKELAQAARAAEGESRQKFFTQDINGILLDIEAQTRELSSQVRSGVYAYLASFLPCSKDALLKRARKLHLYEQGGRLKEPLQKLKEAIGRAMPEQMAKYQDECQAHTQAKVAKMLEEEKDKEQRDRICSDEEEDEEKGGRRIMGPRKKFQWNDEIRELLCQVVKIKLESQDLERNNKAQAWEDCVKGFLDAEVKPLWPKGWMQARTLFKESRRGHGHLTSILAKKKVMAPSKIKVKESSTKPDK--------KVSVPSGQIGGPIALPSDHQTGGLSIGASSRELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSKELAALNSRAAG---NSEFTLPAPSKAP---AEKVGGVLCTEEKRNFAKPSPSAPPPASSLQSPLN------------------FLAEQALALGQSSQEKKPESSGYKELSCQAPLNKGLP-EVHQSKAKHHSLPRTSHGPQVAVPVPGP----QVKVFHAGTQQQKNFTPPSPFANKLQG---PKASPTQCHRSLLQLVKTAAK-------------GQGFHPSAPATSGGLSASSSSS---------------HKTPASSSSALSHPAKPHSVSSAGSSYKNNPFAS---------SISKHGVSSG----------SSSSGG-TPVQSSVSGSLVPGIQPPSVG-----------QATSRPVPSSAGKKMPVSQKLTLVAPPG-------------------------GPN-----GDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGS---SLMASPYKSSSPKLS-GAMSSNSLGIITPVPIPVHVLSFSADSSAKAGVSKDAIVTGPAPGSFHHGLGHSLLAGLHSS-PPHAAPLPHAAVPTHIPQSLPGASQLHGKGPAVPRKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A666-1", "uniprot_id": "UBN2_RAT", "id": "D4A666-1", "name": "Ubinuclein-2", "aln": "---MAEPRRVAFISLSPVRRREADFAGAEREP------PRLEPQPYREPARAEP------APRADAQPPARDKPLPQREVSRAEPPMALQREPPRPEPPP--PPLPLQTPPPRESASRAEPPPRPPKETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKLVHT---------EDPFTDEHKERQEVEMLAKKFEMKYGGKARKHRKD-RLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDFTDNQKHKPPKVPK--IKDDDIEAKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESTPKVPVIPSTSSLPKPPCAATTLGDDIPDLSLNSADPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDATSDGSPLSESGGENGNTTQPTFASQVVPKVVPTLPDGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADE----EREKNGSDDD-DDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPN-KSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPASKPKVKEVMVKTLPVRSFPTMLKECSPKKDPKAPASVVASG--GCPCTSSSTSIVASASSSSTPAQETICLDDSLDEDLS-LPSASLDLVSEALAVINNGNKGPSVSSRLNVPTTKPRPGLREEKLASIMSKLPLATPKKLDSPQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSS-QTHVSSS-QAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSQLLKTSEKPLMYRLPLSTPSPGNGSQGSHPLVSRTAPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLTSPKPSVSPKPSLSAKPSVSTKLISKSNPTPKPAVCPSSSSPNTLVAQSSHSTSNNPAHKQPSGMNISRQSPTLNLLPSNRTSGLPTTKTLQAPSKLTNSSSAGTVGKNSLSGIPVNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLST-PHRPTSASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQTVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTATS------GSTSAALHHGLTQNLLKSLQPG-TQHAATLPHSPLPTHLQQAFNDGGQSKGD-TKLPRKPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WC1-1", "uniprot_id": "UBN2_MOUSE", "id": "Q80WC1-1", "name": "Ubinuclein-2", "aln": "---MAEPRRVAFISLSPVRRREADFAGAEREP------PRLEPQPYREPARAEP------APRADAQPPARDKPLPQREVSRAEPPMALQREPPRPEPPP--PPLPLQTPPPRESASRAEPPPRPPKETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKLVHT---------EDPFTDEHKERQEVEMLAKKFEMKYGGKARKHRKD-RLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDFTDNQKHKPPKVPK--IKEDDIEVKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESTPKVPVTPSSSSLPKPPCVTTALGDDIPDLGLNSADPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDATSDGSPLSESGGENGNTTHPTFPSQVVPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADE----EREKNGSDDD-DDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPN-KSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPASKPKV-----------------KECSPKKDPKAPASVVASG--GGPSTSSSTSIVASASSSSAPAQETICLDDSLDEDLS-FPSASLDLVSEALAVINNGNKGPSVGSRLNVPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSSSQTHVSSS-QAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSQLLKTSDKPLMYRLPLSTPSPGNGSQGPHPLVSRTAPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSVSPKPSLSAKPSISTKQISKSNPAPKPAVCPSSSSPNTLVAQSSHSTSNNPVHKQPSGMNISRQSPTLNLLPSNRTSGLPTTKTLQAPSKLTNSSSTGTAGKNSLSGIPMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLST-PHRPTSASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQTVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTATS------GSTSAALHHSLTQNLLKSLQPG-AQHAAALPHSPLPAHLQQAFNDGGQSKGD-TKLPRKPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZU65-1", "uniprot_id": "UBN2_HUMAN", "id": "Q6ZU65-1", "name": "Ubinuclein-2", "aln": "---MAEPRRVAFISLSPVRRREAEYPGPEREPEYPREPPRLEPQPYREPARAEPPAPREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKLIHT---------EDPFNDEHQERQEVEMLAKKFEMKYGGKPRKHRKD-RLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDITDNQKHKPPKVPK--IKEDDIEMKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESNPKVPVTLSTPSLNKPPCAAAALGNDVPDLNLSSGDPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDAASDGSPLSESGGENGTTTQPTYTSQVMPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQTDE----EREKNGSEED-DDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPN-KSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPAPKPKVKEVMVKTLPLHSFPTMLKECSPKKDQKTPTSLVASV--SGPPTSSSTAAIAAASSSSAPAQETICLDDSLDEDLS-FHSPSLDLVSEALAVINNGNKGPPVGSRISMPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTTHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHTSSSSQTHVSSSSQAQIAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSSLIKTSDKPLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSASPKPSLSAKPSVSTKLISKSNPTPKPTVSPSSSSPNALVAQGSHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSGLPPTKNLQAPSKLTNSSSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLST-PHRPSTASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGLVPVTMPFQFPLEIFGFGTDTAGVTTTS------GSTSAAFHHSLTQNLLKGLQPGGAQHAATLSHSPLPAHLQQAFHDGGQSKGD-TKLPRKSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25992-1", "uniprot_id": "YEMA_DROME", "id": "P25992-1", "name": "yemanuclein", "aln": "MSKGGEHKRVTLTSIIQGDAG----------------FSRFGSNILEPDAASAAP-------------------------------------------------------------DNSSKPTTKTAKCIRIKLDLFETDSNKYPEFNYSRLLYLEKKKTKKLKQVSTTNGSASTDPFADNDDD---VARIVKELEAKYGNSYATGRGKSKKDDYRDIGMGYDESDSFIDNTEAYDEIIPEEAETLEGGFYINCGALEFKNLTKKSYTTRTDAIIKMPERSRKRMVSSSSESSSSSSGDDDENDDGNNEEDDESDSEDDSEENDESDSEDDSESESLEDEDSAATAKSSSKYKDNHQAKRAKVIVTG-----------KSKPSSSSLTSGKKPPTKPITTSSSSN------------------------SPRPSTVEISDTEDGQDPIQTQPSSQLQSLPQSQAQAQALKKVVKTTTVKDMLKAKRDS-----FLKSQSGTAAVKGVGNGELKCVSTD--VSSSDSSDMESEHGRADRQAGQHGKDGQENLRTADTLLPTTLDADIVTAVNSFKEAVKSRDMCG------------------------------------KKFNLDVKLSPLLLRVYEAVLCTDRNERN----------MVFSHIEYQLQLPKYYMLRKGKQVRAKEEKRKSTIMLEKLRRAVA-----------------------VVMPKAVANYETELRTFAEQAAADVNSELPPKMPRKKFQWTSELRHLLYDVYQARWT--SYAFLAKRKESLEEFIN------WYLKEKVVELWPPGWMRLDELQREITRYKNAKLKAKEKPKAPPASASPKPVG--------------------------VVSAPEQMPPASSYLKAVE--DPRSRGNSDTDSATSASSNSLKRKLKEMPKQTSKPPK------KKVAKQVPLQPQLTPHP------------QFQLAPAATAAVSIPAISNN-----------------NNHLPHLDTLLSMPSTSA----------------QAAALNAAAVAAASTVLDLASPSRKIDLN---------------------------------TSNNFYNLITAASLAASGNPSPHSGDGQ----------AKVIVGARPSPHVINLDDYQCTSDILQTS-------------------------------------KQLAATTTVITAISKAAQTTSVARESSSESDGVEIVGVFPASKPQKKVQS--KPKNKTQNRGRSSLGAVGQVN------GSLGYSANNMYIYNSP-------RTLGPVYDLTDPHIMKTMSNLKEMEKQFIQAAFSPNSVKGASGGMG---SSAPSTPTRQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :** : *: : . . . . :*: * * :. : ** *..*: . : * :: *** *:..: * :.:::* ***.. . * . : :* *:* ****:*.****:*****::* . * ****** *:*:*:: :... . : . : * :.... . .. . .: :.: : .:. .. : : : :.:.. . :*. . :.... .:.. : * . . .* . * .: *:..: :. *.. . :* . . .. . . : .:. . : : : . * :. .. ** . : : .:. .* * .*: . * ::. : : .::: ::: . ***: : : ** .: : * * * * . * : ** :* : .:: : : * * : . *. : : . .:. . . . * * : . : .: * : . . .: ::: : . . . .. :.: . . : * : :. . . :.: . . : . * . * .:* : . .: : : : * . . .::*: ::. ::: .:. :* . : :.. . .* : : * : . . . . . : .. ..:. ::: . . :.* :: ... . ::. . : * . .. . . : :.:.::. . : ...:. :: : . : : . : : . . .. . * : ", "identical_positions": 96, "similar_positions": 320, "identity": "6.96%" }, { "cls_id": "homologset.agr.FB:FBgn0005612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04890-1", "uniprot_id": "SOX12_MOUSE", "id": "Q04890-1", "name": "Transcription factor SOX-12", "aln": "------------------------------------------------------MVQQRG---------ARAKRDGGP---------PPPGPGPAAEG-AREPGWCKTPS--------------------------------------------------------------------------GHIKRPMNAFMVWSQHERRKIMDQWPDM-----HNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARP------RP-------------------------PGGGGGGSR-----LKPGPQLPGRGGRRASGG------------PLGGG--------------------AAAPEDDDED---------------------------------------------------EEEELLEVRLLETPGRE--------------------------LWR-----MVPAGRAARGPAERAQGPSGEG--------------------AAASAASPTLSEDEEPEEEEEEAATAEEGE---EETVVSGEEPLGFLSRMPPGP------------------AGLDCSALDRDPDLLPPSGT-SHFEFP---------------DYCTPEVTEMIAGDWRSSSIADLVFTY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15370-1", "uniprot_id": "SOX12_HUMAN", "id": "O15370-1", "name": "Transcription factor SOX-12", "aln": "------------------------------------------------------MVQQRG---------ARAKRDGGP---------PPPGPGPAEEG-AREPGWCKTPS--------------------------------------------------------------------------GHIKRPMNAFMVWSQHERRKIMDQWPDM-----HNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARP------RP-------------------------PGGSGGGSR-----LKPGPQLPGRGGRRAAGG------------PLGGG--------------------AAAPEDDDED---------------------------------------------------DDEELLEVRLVETPGRE--------------------------LWR-----MVPAGRAARGQAERAQGPSGEGA-------------------AAAAAASPTPSEDEEPEEEEEEAAAAEEGE---EETVASGEESLGFLSRLPPGP------------------AGLDCSALDRDPDLQPPSGT-SHFEFP---------------DYCTPEVTEMIAGDWRPSSIADLVFTY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZQY6-1", "uniprot_id": "A0A8I5ZQY6_RAT", "id": "A0A8I5ZQY6-1", "name": "Transcription factor SOX", "aln": "------------------------------------------------------MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPS--------------------------------------------------------------------------GHIKRPMNAFMVWSQIERRKIMEQSPDM-----HNAEISKRLGKRWKLLKDSDKIPFIQEAERLRLKHMADYPDYKYRPRKKVKSGNTGAGS--AATAKPGEKGDKVAG--GSGHAG-----SGHAGGGAGGSS------KPAPKKS-CGPKVAGSS---VGKPHAKFVPAGGG-------------------KAAASFSPEQA---ALLPLGEPA--------AVYKVRTPSAATPAASS-SPSSALATPAKHPADKKVKRVYLFGSLGASASPVGGLG--------ASADPSDPLGLYEDGGPGCSPDGRSLSGRSSAASSPAASRSPADHR------------GYASLRAASPAPSSAPSHASSSLS--SSSSSS---SGSSSSDDEFEDDLLDLNPSSNFESMSL----------GSFSSSSALDRDLDFNFEPGSGSHFEFP---------------DYCTPEVSEMISGDWLESSISNLVFTY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06831-1", "uniprot_id": "SOX4_MOUSE", "id": "Q06831-1", "name": "Transcription factor SOX-4", "aln": "------------------------------------------------------MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPS--------------------------------------------------------------------------GHIKRPMNAFMVWSQIERRKIMEQSPDM-----HNAEISKRLGKRWKLLKDSDKIPFIQEAERLRLKHMADYPDYKYRPRKKVKSGNAGAGS--AATAKPGEKGDKVAG--SSGHAG-----SSHAGGGAGGSS------KPAPKKS-CGPKVAGSS---VGKPHAKLVPAGGS-------------------KAAASFSPEQA---ALLPLGEPT--------AVYKVRTPSAATPAASS-SPSSALATPAKHPADKKVKRVYLFGSLGASASPVGGLG--------ASADPSDPLGLYEDGGPGCSPDGRSLSGRSSAASSPAASRSPADHR------------GYASLRAASPAPSSAPSHASSSLS--SSSSSS---SGSSSSDDEFEDDLLDLNPSSNFESMSL----------GSFSSSSALDRDLDFNFEPGSGSHFEFP---------------DYCTPEVSEMISGDWLESSISNLVFTY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06945-1", "uniprot_id": "SOX4_HUMAN", "id": "Q06945-1", "name": "Transcription factor SOX-4", "aln": "------------------------------------------------------MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPS--------------------------------------------------------------------------GHIKRPMNAFMVWSQIERRKIMEQSPDM-----HNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKS-CGSKVAGGAGGGVSKPHAKLILAGGGGGGKAA------------AAAAASFAAEQAGAAALLPLGAAAD-----HHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVG--------AGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHR------------GYASLRAASPAPSSAPSHASSSASSHSSSSSS---SGSSSSDDEFEDDLLDLNPSSNFESMSL----------GSFSSSSALDRDLDFNFEPGSGSHFEFP---------------DYCTPEVSEMISGDWLESSISNLVFTY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C1G9-1", "uniprot_id": "SOX11_RAT", "id": "P0C1G9-1", "name": "Transcription factor SOX-11", "aln": "------------------------------------------------------MVQQAESSE-AESNLPRDALDTEEG---------EFMACSPVALDESDPDWCKTAS--------------------------------------------------------------------------GHIKRPMNAFMVWSKIERRKIMEQSPDM-----HNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKKPKTDPAAKPS---AGQSPDK---------------------SAAG------------AKAAKGPGKKCAKLKAPAG-----------KAGAG-------------------KAAQPGDCG--------------------AGKAAKCVFLDDDDEEDDEDDELQLRPKPDADDDDDEPAHSHLLPPPAQQQ----------------------PPQLLRRYSVAKVPASPTLSSAAESPEGASLYDEVRAGG--------RLYYSFKNITKQQPPP-APPALSPASSRCVSTSSSS--GSSSGSGAEDADDLMFDLSLNFSQGAHSACEQPLGAG-AAGNLSLSLVDKDLDSFSEGSLGSHFEFP---------------DYCTPELSEMIAGDWLEANFSDLVFTY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M6Y2-1", "uniprot_id": "SOX11_MOUSE", "id": "Q7M6Y2-1", "name": "Transcription factor SOX-11", "aln": "------------------------------------------------------MVQQAESSE-AESNLPRDALDTEEG---------EFMACSPVALDESDPDWCKTAS--------------------------------------------------------------------------GHIKRPMNAFMVWSKIERRKIMEQSPDM-----HNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKKPKTDPAAKPS---AGQSPDK---------------------SAAG------------AKAAKGPGKKCAKLKAPAG-----------KAGAG-------------------KAAQPGDCA--------------------AGKAAKCVFLDDDDEDDDEDDELQLRPKPDADDDDDEPAHSHLLPPPTQQQ----------------------PPQLLRRYSVAKVPASPTLSSAAESPEGASLYDEVRAGG--------RLYYSFKNITKQQPPP-APPALSPASSRCVSTSSSS--GSSSGSGAEDADDLMFDLSLNFSQGAHSACEQPLGAG-AAGNLSLSLVDKDLDSFSEGSLGSHFEFP---------------DYCTPELSEMIAGDWLEANFSDLVFTY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35716-1", "uniprot_id": "SOX11_HUMAN", "id": "P35716-1", "name": "Transcription factor SOX-11", "aln": "------------------------------------------------------MVQQAESLE-AESNLPREALDTEEG---------EFMACSPVALDESDPDWCKTAS--------------------------------------------------------------------------GHIKRPMNAFMVWSKIERRKIMEQSPDM-----HNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKKPKMDPSAKPS---ASQSPEK---------------------SAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAA--------GAKAGAG-------------------KAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQ-----------------------PSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFP---------------DYCTPELSEMIAGDWLEANFSDLVFTY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40656-1", "uniprot_id": "SOX14_DROME", "id": "P40656-1", "name": "Putative transcription factor SOX-14", "aln": "MIAKPNQATTEPPLSLRPGTVPTVPATTPARPATITIQRRHPAPKADSTPHTLPPFSPSPSPASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEPRSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDL-----HNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQKKQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAING---TTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGKPLNEPVFDSEDNIVNDANLHSASHQIPPYVPDSHDCFAEDCGGDSSSHQVEFEVVRPQTVTMTMTCTLPYGGPDAGHTTFQADDFNAIPSAAEDSECSILTTSNSPQIGFNGSSFVEADAIGSTCTYAQQDYTGSVIETHNDLNYAAHDNNGALLAYTFEDLPPQPTGSHLEFNTNKYEFASYYKM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25042-1", "uniprot_id": "ROX1_YEAST", "id": "P25042-1", "name": "Repressor ROX1", "aln": "-----------------------------------------------------------------------------------------------MNPKSSTPK----------------------------------------------------------------------------------IPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQK----------------------EQQQQKQSQPQLQQPFNNNIVLMKRAHSLSPSSS----------VSSSNS--------------------YQFQLNNDLK-----------------------RLPIPSVNTSNYMVSRSLSGLPLTHDKTARDLPQLSSQLNSIPYYSAP--------------------HDPSTRHHYLNVAQAQPRANSTPQLPFISSIINNSSQTP-----------VTTTTTSTTTATSSPGKFSSSPNSSVLENNRLNSINNSNQYLPPPLLPSLQDFQLDQYQQLKQMG----------PTYIVKPLSHTRNNLLSTTTPTHHHIP-------------HIPNQNIPLHQIINSSNTEVTAKTSLVSPK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ** ***::: : :* : :. . **::*** :* :*: *. .:* : **: : * .**:***:* :* . . . . . . . : . . :. : . : .. . .: ", "identical_positions": 27, "similar_positions": 44, "identity": "3.99%" }, { "cls_id": "homologset.agr.FB:FBgn0005613", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTE1-1", "uniprot_id": "D3ZTE1_RAT", "id": "D3ZTE1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MASLLGAYPWTEG------------LECPALEAELS-------DGLSPPAVPRPSGD--------------------------------------------KGSESRIRRPMNAFMVWAKDERKRLAVQNPDL-----HNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQGKRLCKRVDPGFLLSSLSRDQN--------------------------------TLPEKNSIGRGPLGEKEDRGEYAPGATLP----------------GLHSCYREGAAAAPG-----SVDTYPYGLPTPPEMSPLDALEP-EQTFFSSSCQEEHGHPHHLPHLPGPPYSPEFTPSP-----L-----------------------------------------HCSHPLGSLALGQSPGVSMMSSVPGCPPSPAYYSHATYHPLHPN-------------------LQAHLGQLSPPPEHPGFDTLDQLSQ-VELLGDMDR----------------------------------------------------------------NEFDQYLNTPGHPDSASGVGTLTGHAPLSQGTPTGPTETSLISVLADATATYYNSYSVS-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40646-1", "uniprot_id": "SOX7_MOUSE", "id": "P40646-1", "name": "Transcription factor SOX-7", "aln": "-----------------------------------------------------------------------------------------------------------MASLLGAYPWTEG------------LECPALEAELS-------DGLSPPAVPRPSGD--------------------------------------------KSSESRIRRPMNAFMVWAKDERKRLAVQNPDL-----HNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQGKRLCKRVDPGFLLSSLSRDQN--------------------------------TLPEKNGIGRG---EKEDRGEYSPGATLP----------------GLHSCYREGAAAAPG-----SVDTYPYGLPTPPEMSPLDALEP-EQTFFSSSCQEEHGHPHHLPHLPGPPYSPEFTPSP-----L-----------------------------------------HCSHPLGSLALGQSPGVSMMSSVSGCPPSPAYYSHATYHPLHPN-------------------LQAHLGQLSPPPEHPGFDTLDQLSQ-VELLGDMDR----------------------------------------------------------------NEFDQYLNTPGHPDSAAGVGTLTGHVPLSQGTPTGPTETSLISVLADATATYYNSYSVS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT81-1", "uniprot_id": "SOX7_HUMAN", "id": "Q9BT81-1", "name": "Transcription factor SOX-7", "aln": "-----------------------------------------------------------------------------------------------------------MASLLGAYPWPEG------------LECPALDAELS-------DGQSPPAVPRPPGD--------------------------------------------KGSESRIRRPMNAFMVWAKDERKRLAVQNPDL-----HNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQN--------------------------------ALPEKRSGSRGALGEKEDRGEYSPGTALP----------------SLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEP-EQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSP-----L-----------------------------------------HCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSN-------------------LQAHLGQLSPPPEHPGFDALDQLSQ-VELLGDMDR----------------------------------------------------------------NEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V923-1", "uniprot_id": "G3V923_RAT", "id": "G3V923-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MSSPDAGYASDDQSQPRS--------AQPAVMAGLG--PCPWAESLSSLGDVKVKGEVVASSGAP-----------------------------AGTSSRAKA-ESRIRRPMNAFMVWAKDERKRLAQQNPDL-----HNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKR-MKRVEGGFLH-ALAEPQAG------------------------------ALGPEGGRVAMDGLGLPFPEPGYPAGPPLMSP--------------HMGAHYRDCQGLGAP-----ALDGYP--LPTP-DTSPLDGVEQ-DPAFFAAPLPGDCPAAGAYTYAQVSDYAVPAEPSAGPMR-------------------------------------------VGPDPSGSAMPGILAPPSALHLYYGAMGSPAASAGRGFHAQPQQPLQPQPPPPPPPPPPPQQHPTHGPGQPSPPPEALPCRDGTEPNQPTELLGEVDR----------------------------------------------------------------TEFEQYLHFVYKP--EMGLPYQGHDCGVN----LSDSHGAISSVVSDASSAVYYCNYPDI----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61473-1", "uniprot_id": "SOX17_MOUSE", "id": "Q61473-1", "name": "Transcription factor SOX-17", "aln": "-----------------------------------------------------------------------------------------------------------MSSPDAGYASDDQSQPRS--------AQPAVMAGLG--PCPWAESLSPLGDVKVKGEVVASSGAP-----------------------------AGTSGRAKA-ESRIRRPMNAFMVWAKDERKRLAQQNPDL-----HNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKR-MKRVEGGFLH-ALVEPQAG------------------------------ALGPEGGRVAMDGLGLPFPEPGYPAGPPLMSP--------------HMGPHYRDCQGLGAP-----ALDGYP--LPTP-DTSPLDGVEQ-DPAFFAAPLPGDCPAAGTYTYAPVSDYAVSVEPPAGPMR-------------------------------------------VGPDPSGPAMPGILAPPSALHLYYGAMGSPAASAGRGFHAQPQQPLQPQAPPPPP----QQQHPAHGPGQPSPPPEALPCRDGTESNQPTELLGEVDR----------------------------------------------------------------TEFEQYLPFVYKP--EMGLPYQGHDCGVN----LSDSHGAISSVVSDASSAVYYCNYPDI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6I2-1", "uniprot_id": "SOX17_HUMAN", "id": "Q9H6I2-1", "name": "Transcription factor SOX-17", "aln": "-----------------------------------------------------------------------------------------------------------MSSPDAGYASDDQSQTQS--------ALPAVMAGLG--PCPWAESLSPIGDMKVKGEAPANSGAP-----------------------------AGAAGRAKG-ESRIRRPMNAFMVWAKDERKRLAQQNPDL-----HNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKR-LKRVEGGFLH-GLAEPQAA------------------------------ALGPEGGRVAMDGLGLQFPEQGFPAGPPLLPP--------------HMGGHYRDCQSLGAP-----PLDGYP--LPTP-DTSPLDGVDP-DPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPR-----------------------------------------LGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPP-----------GPGQPSPPPEALPCRDGTDPSQPAELLGEVDR----------------------------------------------------------------TEFEQYLHFVCKP--EMGLPYQGHDSGVN----LPDSHGAISSVVSDASSAVYYCNYPDV----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V7E4-1", "uniprot_id": "Q4V7E4_RAT", "id": "Q4V7E4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MQRSPPGYGAQDDPPSRRDCAWAPGLGAAAEPRGL---PVTNVSPTSPASPSSLPRSPPRSPESGRYGF--------------------------GRGERQTADELRIRRPMNAFMVWAKDERKRLAQQNPDL-----HNAVLSKMLGKAWKELNTAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARK-VRRLEPGLLLPGLVQPSA-------------------------------------------------PPEPFAAAS-------------------GSARSFRELPTLGA------EFDGLG--LPTP-ERSPLDGLESGEASFFPPPLAPEDCALRAFR-APYAP-ELARDPSF-----------------------------------------------CYGSSLAEALRTAPPAAPLAGLYYGTLGTPGP----------------------------------FPNPLSPPPEAPSLEGTEQLEPTADLWADVDL----------------------------------------------------------------TEFDQYLNCSRTRPDATALPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43680-1", "uniprot_id": "SOX18_MOUSE", "id": "P43680-1", "name": "Transcription factor SOX-18", "aln": "-----------------------------------------------------------------------------------------------------------MQRSPPGYGAQDDPPSRRDCAWAPGIGAAAEARGL---PVTNVSPTSPASPSSLPRSPPRSPESGRYGF--------------------------GRGERQTADELRIRRPMNAFMVWAKDERKRLAQQNPDL-----HNAVLSKMLGKAWKELNTAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARK-VRRLEPGLLLPGLVQPSA-------------------------------------------------PPEAFAAAS-------------------GSARSFRELPTLGA------EFDGLG--LPTP-ERSPLDGLEPGEASFFPPPLAPEDCALRAFR-APYAP-ELARDPSF-----------------------------------------------CYGAPLAEALRTAPPAAPLAGLYYGTLGTPGP----------------------------------FPNPLSPPPESPSLEGTEQLEPTADLWADVDL----------------------------------------------------------------TEFDQYLNCSRTRPDATTLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35713-1", "uniprot_id": "SOX18_HUMAN", "id": "P35713-1", "name": "Transcription factor SOX-18", "aln": "-----------------------------------------------------------------------------------------------------------MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLS-----------------------PAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDL-----HNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARK-ARRLEPGLLLPGLAPPQP-------------------------------------------------PPEPFPAAS-------------------GSARAFRELPPLGA------EFDGLG--LPTP-ERSPLDGLEPGEAAFFPPPAAPEDCALRPFR-APYAPTELSRDPGG-----------------------------------------------CYGAPLAEALRTAPPAAPLAGLYYGTLGTPGP----------------------------------YPGPLSPPPEAPPLESAEPLGPAADLWADVDL----------------------------------------------------------------TEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40657-1", "uniprot_id": "SOX15_DROME", "id": "P40657-1", "name": "Putative transcription factor SOX-15", "aln": "MEPSYDHEHPHHLLTNYNSKKYPHVSRTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGIYHVRQGSEHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLLGGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDL-----HNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQHCNVVTSTPSSSGGTMPTSEMSSYTVSMADNCGNLRLSMNELSGNEYLPSANAYGMQYEDFLRYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYDDYEAEAYSNAMLPATAASYYTQLPYPPTSLAAFPLQLAVPFQQTTSGAYGAQPIQSGYLHYGNYGGYEGMAQSQPQNQAPVHHQQASHSAPPSLSVPPNQTVTSNSAAISMQQHHHHHFGPAPGMVGVGVGVGVGVGVGEMLFEQQQRKDDEISNILAGVRKTCYSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25042-1", "uniprot_id": "ROX1_YEAST", "id": "P25042-1", "name": "Repressor ROX1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPKSSTPKIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQKEQQQQ------------------------------------------KQSQPQLQQPFNNNIVLMKR----------------AHSLSPSSSVSSSNSYQFQLNNDLKRLPIPSVNTSNYMVSRSLSGLPLTHDKTARDLPQLSSQLNSIPYYSAPHDPSTRHHYLN---------------------------------------VAQAQPRANSTPQLPFISSIINNSSQTPVTTTTTSTTTATSSPGK-------------------FSSSPNSSVLENNRLNSINNSNQYLPPPLLPSLQD----------------------------------------------------------------FQLDQYQQLKQMGPTYIVKPLSHTRNNLLSTTTPTHHHIPHIPNQNIPLHQIINSSNTEVTAKTSLVSPK------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* ** ***::: : :: * : . **: :**::*. *: * :: : : **: :: * .:*:***:* *:.: : : : . .. * : : . . . . : . : : * . . . ", "identical_positions": 25, "similar_positions": 49, "identity": "3.17%" }, { "cls_id": "homologset.agr.FB:FBgn0005614", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58GIR7-1", "uniprot_id": "A0AC58GIR7_DANRE", "id": "A0AC58GIR7-1", "name": "", "aln": "---MSQQYFRRTENFLYRDRIPLRIVRSESELSP------LEKAYLWAVEKGDYGSVKQALIEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGGMQVPP--ILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSMPQPHQVRCNCMECVSSSDVDSLRHSRSRLNIYRALASPSLVALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSQQCKQFAKDLLDQTRSSRELELILNYKDDIN-LLEDEGINDLARLKLAIKYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWASKFMTCIFIGLLFPFFSLFYLIAPKSHYGLFIRKPFIKFICHTASYLTFLFLLLLASQHVNRNLLDQD-----ENSDCKNENLRQNLAPTTVEWMILPWVLGFVWAEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVALSKYN-NQCRD---------EWDMWHPALVGEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYESD--------GKTSNNVTCKGIRCSEQNNAFTTMFETLQSLFWSIFGLVALHVTNVDAKHDFTEFVGATMFGTYSIISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNVVPSPKSAWYLIRWIKTHCFKIKQR------KRTETLGSLGVRGHFLLMLYSFIFHYMLTNFLFTEYYIYINNAFGFHYHIIKQSVLKKAIQLFSFVQIRAAENVRTNRQYQEVLRNLVKRYVAARIRDAKKEEGLTEDNFKELKQDISSFRYEVMGMMKGTKTGMSTSK--------------------GNTAESSLVYPENALKCNSTSTGSTLKGKMRLQS---------------------ITNTMIQEGGPKAWKPTG---CSNLADSSVPNKNISHQLN--------------------CKGPN---------NPGEMYSVSEEAGESESE---EQGDGKQ-----------AENLDCK---------------------KKKNQNKETEKDGV----------NNDVEEDEELTYMRYMCEEEMNEGNEGETSRL----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IM91-1", "uniprot_id": "A0A0R4IM91_DANRE", "id": "A0A0R4IM91-1", "name": "", "aln": "---MSQLYFRRTDNSSYRDRIPLRIVRAESELST------QEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP--ILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDDMN-LLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSNNPD-----------------RQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCKPRD---------TWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEN------------SEGMTCKGIRCERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVFKRRS-------KRKETFGTLGRR---------------------------------------------------------AAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGNRKSTRANK--------------------SDTSASDVSHPEGSLQYSSALK---QNSKLHLYD---------------------VTTALQQQNSEEAKASLG---CLANGSAVVLTEPILKDKARSDFPKD-------FTDFGLFPKKQ---------NPNKIYSLAEEATESDPD---ILDWGKE-----------DKPLAGK---------------------VEQDVNESKCLMEE----------DERVLEEQEMEHIASSHEH-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35119-1", "uniprot_id": "TRPC4_RAT", "id": "O35119-1", "name": "Short transient receptor potential channel 4", "aln": "---MAQFYYKRNVNAPYRDRIPLRIVRAESELSP------SEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP--ILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNS-LIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLN-----------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRE---------SWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEE------------TKGLSCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTDFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMR------RKPESFGTIGRR---------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQS---------------------ANAASSAS-SADSDEKSHSEGNGKDKRKNLSLFD---------------------LTTLIHPRSAVIASERHN---LSN-GSALVVQEPPREKQRKVNFVAD-------IKNFGLFHRRSK--QNAAEQNANQIFSVSEEITRQQAAGALERNIQLE-----------SKGLASRGDRSIPGLNEQCVLV------DHRERNTDTLGLQVGKRVCSSFKSEKVVVEDTVPIIPKEKHAQEEDSSIDYDLSPTD---TVAHEDYVTTRL------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUQ5-1", "uniprot_id": "TRPC4_MOUSE", "id": "Q9QUQ5-1", "name": "Short transient receptor potential channel 4", "aln": "---MAQFYYKRNVNAPYRDRIPLRIVRAESELSP------SEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP--ILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNS-LIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLN-----------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRE---------SWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEE------------TKGLSCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMR------RKPESFGTIGRR---------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQS---------------------ANAAS----SADSDEKSQSEGNGKDKRKNLSLFD---------------------LTTLIHPRSAAIASERHN---LSN-GSALVVQEPPREKQRKVNFVAD-------IKNFGLFHRRSK--QNAAEQNANQIFSVSEEITRQQAAGALERNIELE-----------SKGLASRGDRSIPGLNEQCVLV------DHRERNTDTLGLQVGKRVCSTFKSEKVVVEDTVPIIPKEKHAHEEDSSIDYDLSPTD---TAAHEDYVTTRL------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBN4-1", "uniprot_id": "TRPC4_HUMAN", "id": "Q9UBN4-1", "name": "Short transient receptor potential channel 4", "aln": "---MAQFYYKRNVNAPYRDRIPLRIVRAESELSP------SEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP--ILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNS-LIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLN-----------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRE---------SWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEE------------TKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMR------RKPESFGTIGRR---------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQS---------------------ANASKESSNSADSDEKSDSEGNSKDKKKNFSLFD---------------------LTTLIHPRSAAIASERHN---ISN-GSALVVQEPPREKQRKVNFVTD-------IKNFGLFHRRSK--QNAAEQNANQIFSVSEEVARQQAAGPLERNIQLE-----------SRGLASRGDLSIPGLSEQCVLV------DHRERNTDTLGLQVGKRVCP-FKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPD---TVTHEDYVTTRL------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UL62-1", "uniprot_id": "TRPC5_HUMAN", "id": "Q9UL62-1", "name": "Short transient receptor potential channel 5", "aln": "---MAQLYYKKVNYSPYRDRIPLQIVRAETELSA------EEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPT--LMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH-----------------VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPRE---------EWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYET---------RAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDP---DGRRRRRNLRSFTER---------------------------------------------------------NADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRKHPR-SFS--------------------TSSTELSQRDDNNDG-----SGGARAKSKSVSFN--------------------LGCKKKTCHGPPLIRTMPR--------SSGAQGKSKAESSSKRSFMGP------SLKKLGLLFSKFNGHMSEPS--SEPMYTISDGIVQQHCMWQDIRYSQME---------KGKAEACSQSEINLSEVELG-----------EVQGAAQ-SSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHK----WGDGQEEQVTTRL------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QX29-1", "uniprot_id": "TRPC5_MOUSE", "id": "Q9QX29-1", "name": "Short transient receptor potential channel 5", "aln": "---MAQLYYKKVNYSPYRDRIPLQIVRAETELSA------EEKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPT--LMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH-----------------VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPRE---------EWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYET---------RAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDP---DGRRRRHNLRSFTER---------------------------------------------------------HADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRRSLS--------------------TSSADFSQRDDTNDG-----SGGARAKSKSVSFN--------------------VGCKKKACHGAPLIRTVPR--------ASGAQGKPKSESSSKRSFMGP------SFKKLGLFFSKFNGQTSEPT--SEPMYTISDGIAQQHCMWQDIRYSQME---------KGKAEACSQSQMNLGEVELG-----------EIRGAAARSSECPLACSSSLHCASGICSSNSKLLDSSEDVFETWGEACDLLMHK----WGDGQEEQVTTRL------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AXK0-1", "uniprot_id": "A0A8M3AXK0_DANRE", "id": "A0A8M3AXK0-1", "name": "", "aln": "MNPMSHLYYKKSSYSPYRDRIPLQIVRAEVELSP------EERAFLSAVEKGDYAGVQHALREAEVYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPS--LMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDDQSEELDPRECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH-----------------MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNSSRPRE---------EWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYET---------EAADEPNHCKGIRCERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWVHGRLCGSETAPPEEDTHKHENLKEFTEK---------------------------------------------------------HADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDLLGNRKPPRRNYS--------------------SSSEATLRDEVSDDGEARHHSDGSSIGAKGVSFKTITPSDPSYGVSALFHSISGMEAAGTTREGKPKINGLRKNPSPSSSLSSVAPARAPALSRTWRRFSRFSSSKKNSFRRLGLLFSRMGSHLPQPTGVTAATYTISDGLLHPPGAWHDLGFTRGDGPV-----TRSETNLNQVATLNEGGIGIGGSGVGMSTNGQRANGRDVLLTLGPLSPPSSLHCASSFSASSSRLLDSNEDVFQGLVGPCVGQMPHSSSCWVTEQDDSVTTQL------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48994-1", "uniprot_id": "TRPL_DROME", "id": "P48994-1", "name": "Transient-receptor-potential-like protein", "aln": "MGRKKKLPTGVSSGVSHASSAPKSVGGCCVPLGLPQPLLLEEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYDPQMS-SYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKCYVLPGGEADWGSHGDSCMKWR-RFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPSVKWVIRIFRKSSKTIDRQRSK------KRKE---------------------------------------------------------------------QEQFSEYDNIMRSLVWRYVAAMHRKFENNP-VSEDDINEVKSEINTMRYEMLEIFENSGMDVSSANKKERQPRPRRIKVWERRLMKGFQVAPVQNGCELDAFGNVNGQGEMQEIKVESIPSKP------------AKETAKERFQRVARTVLLQSTTHKWNVVLRAAKDSQIGRCTKNERKSLQNLGRAIEEAKRLIMLNPGCPSGRESPIRIEFEDEKTSTLLELLNQISAEISDSEKPKIRPIWRPPLKTVPARAMAANNTRSLTAPELKISRKSSPAPTPTPTPGVSHTALSQFRNRELPLCPSKLIANSAPSAPTAPPKKSAPTAPTPTYKPTTHAPFSVEGGNRENTRASDGVRSDNSNFDIHVVDLDEKGGHLGRDNVSDISSIASTSPQRPKHRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * : . *. *: :* ***:** *: * :* : ::: **:***** ** :**:*****::***: .* . ****:**. *.* ******.:.. * :* : : *:*****::****.**:**:::*::: .::* **::**.* *** : ****** **:***:**.****:.*:*:**::***:*.***::*: .*:* : ** :* :**: ** *****:*:*.** ***. : . : .*::* **.*:**:***:.* ****:: *** :**:**: . *.: :..:**. .: *: :*.. * :::***:**: *::*** ***:*:*.**: :. *: :* ::: :*:**:* *::::: *: .*::: **::** ****::.:.*: .* : *: *. :.* *:.*.:** :*::*:*:*: **: *.************::**:**:*** ***:*** ***** :*: .:* * . . * .:**: *****: **:: * ::.. :.:* * * ***:*.:*.::****:*****.*** * :*:* **************::..***.***::** * : . :: . .*::::*.** ****: *. :. ::*::.:*:*.:*.::*:*:: :: . : . . . :: : . . .. ", "identical_positions": 304, "similar_positions": 247, "identity": "25.04%" }, { "cls_id": "homologset.agr.FB:FBgn0005616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCI7-1", "uniprot_id": "MSL2_HUMAN", "id": "Q9HCI7-1", "name": "E3 ubiquitin-protein ligase MSL2", "aln": "-MNPVNATALYISASRLVLNYDPGDP-KAFTEINRLLPYFRQSLSCCVC----GHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCK---DYEQFEENKQLSILVNCYKKLCEYITQTTLA-----------RDIIEAVDCS-SDILALLNDGS-------LFCEETEKPSDSSFTLCLTHSPLPS----TSEPTTDPQASLSPMSESTLSIAIG--SSVINGLPTYNGLSIDRFG----INIPSPE-------HSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTG-------------------IDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPN-LEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKT-KPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKG------CKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQN----SYMANGEKK-LEAFAVPEKALEQTRLTLG-------INVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC-------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69ZF8-1", "uniprot_id": "MSL2_MOUSE", "id": "Q69ZF8-1", "name": "E3 ubiquitin-protein ligase MSL2", "aln": "-MNPVNATALYISASRLVLNYDPGDP-KAFTEINRLLPYFRQSLSCCVC----GHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCK---DYEQFEENKQLSILVNCYKKLCEYITQTTLA-----------RDIIEAVDCS-SDILALLNDGS-------LFCEETEKPSDSSFTLCLTHSPLPS----TSEPTADPQASLSPMSESTLSIAIG--SSVINGLPTYNGLSIDRFG----INIPSPE-------HPNTIDVCNTVDIKTEDLSDNLPPVCDTVATDLCSTG-------------------IDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPN-LEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKS-KPGILKKDKAVKEKMPSHHFMPGSPTKTVYKKPQEKKG------CKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQN----SYMANGEKK-LEAFAVPEKALEQTRLTLG-------INVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AT15-1", "uniprot_id": "A0A8I6AT15_RAT", "id": "A0A8I6AT15-1", "name": "", "aln": "MLTLSPVISVYPSLQSSELN-QFQFK-RLISELHYMKLYFSFAKICAFLLPPLGHLLQDPIAPTNSTCQHYVCKSCKGKKMMMKPSCSWCK---DYEQFEENKQLSILVNCYKKLCEYITQTTLA-----------RDIIEAVDCS-SDILALLNDGS-------LFCEETEKPSDSSFTLCLTHSPLPS----TSEPTADPQAALSPMSESTLSIAIG--SSVINGLPTYNGLSIDRFG----INIPSPE-------HPNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTG-------------------IDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCSNLQPN-LEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKLSLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKS-KPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKG------CKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQN----SYMANGEKK-LEAFAVPEKALEQTRLTLG-------INVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50534-1", "uniprot_id": "MSL2_DROME", "id": "P50534-1", "name": "E3 ubiquitin-protein ligase msl-2", "aln": "-----MAQTAYLKVTRIAMRSASNLSKRRVEELNSGLGELRQLLSCVVC----CQLLVDPYSPKGKRCQHNVCRLCLRGKKHLFPSCTQCEGCSDFKTYEENRMMAAQLLCYKTLCVHLLHSALFGELAGMRPQVARELVPRIKLPPKTTQEFIREGSNISDTFDIFLPQPDLPFLKDMPTSLPAETPPTSAVTTPELPYDHHLNISDIEAEAAATAEQGHFSPLPLLPTGSRMGMLSHAGQIVIATESSESGFMDQAWTDQVDLSGTVSVSKYTNSGNNFAVSYVMPTSATTKFDPQELQIGQVVQMADSTQLAVLAAVEETVETSTQLTVLSTTVEETVETSTQLEVLTSAEEPNEISDQLANLQVEESDEALVEETVEEAEGTSIPSEVVAEHMEEDQHLDVHTSQSPTQTEMEEAVEEHVATKTQLGHVQTELQDAESLQKDFEDAKAAAEEAKEKEKDLHAISAELQKEDSDEPTLKRKRTRTLKASQAAKIEPVPSEVKTKVQSGKGALRRIRGKDKEEKVKPPKPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVCCKNPHKEDYVESDEDDDLEDFEMPKDVPEPMTQSEEPVVAEPRQEENSMAPPDSSAPISLVPLNNLQQSQHPLVLVQNEKGEYQGFNIFQGSKPLDPVTVGFTIRVQLQHTDGFGSLPQYAYIMPTIDPPNPPAPSLSPPPPPAPDREVIEPPAKKFRTSRTRRGRANFSALDTVDELVSGGSRSNSAAGDRSSATDNAHSLFEEIMSGSDDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . :. : . *:: : * . :** ** :*... *** **: * * : ***: *: *:: :***: :: : ***.** :: :::* *::: :. . . ::.:** :* :.: * ..:. .*. .. *: *.* . * : :* :. .: : * * : *** . :.: .. * *.* .: :*:..**.:.. *.. .*. .:.*. :. :.:..* ::.. .* : * .::** :: ** . :** :. ::* . : .. :...* : ..:: . : : :*: : *:* :::* :.: . : ..: : .. : .:: :..: .. : . .: : . :.*.* *:.:::: *.. * :.* .:: :: .. : : * :*:* *:** : .. :: ***..*****.. ::* .* * *:* .*: ..*.. ** * :*:.. * : : .*:* ::*:. *:: :.. : . . .:::*. :.::: .. ", "identical_positions": 106, "similar_positions": 242, "identity": "13.55%" }, { "cls_id": "homologset.agr.FB:FBgn0005617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBD0-1", "uniprot_id": "D3ZBD0_RAT", "id": "D3ZBD0-1", "name": "Male-specific lethal 1 homolog", "aln": "-------------------------------------------------------------------------------------------------MTMRSAVFKAAAAPAGGNPEQRLDYERAAALGGPEDESGAAETHFLPRHRKLKEPGPPLASTQGG------------------------------------------------SPAPSPAGCGGGKGRGLLLPAGAAPGQQ--EESWGGSVPLPCPPPATKQAGIG---GEPVAAGAGCSPRPKYQAVLPIQ---------------------------------------------------------TGS-LVAAAKEPTPWAGDKGGAAPPAATASDPAGPPP-------------------------------LPLPGPPPLAPTATAGTLAASEGRWKSIRKSPLGGGGGS----------GASSQAACLKQILLLQLDLIEQQQQQLQAKEK--EIEELKSERDTLLARIERMERRMQLVKRDNEKERH---------KLFQGYEPEEREETELSEKIKLERQPELCETSQALPSKPFSCGRSGKGH------------KRKTPFGNTERKTPVKKLAPEFSKFKTKTPKHSPIKEEPCGSISETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEQAFSSE--------------------------------MEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVA--------------------------------------------------------------------------------------------------------IPSWRDHSVEPLRDPNPSDILENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKG--IQESEPEVTSFFPEPDDVESLMITPFLPVVAFGRPLPKLTP-QNFELPWLD------------------------------ERSRCRLEIQKKQTPHRTCRK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDM1-1", "uniprot_id": "MSL1_MOUSE", "id": "Q6PDM1-1", "name": "Male-specific lethal 1 homolog", "aln": "-------------------------------------------------------------------------------------------------MTMRSAVFKAAAAPAGGNPEQRLDYERAAALGGPEDESGAAEAHFLPRHRKLKEPGPPLASSQGG------------------------------------------------SPSPSPAGCGGGKGRGLLLPAGAAPGQQ--EESWGGSVPLPCPPPATKQAGIG---GEPVAAGAGCSPRPKYQAVLPIQ---------------------------------------------------------TGSIVVAAAKEPTPWAGDKGGAAPPAATASDPAGPPP-------------------------------LPLPGPPPLAPTATAGTLAASEGRWKSIRKSPLGGGGGS----------GASSQAACLKQILLLQLDLIEQQQQQLQAKEK--EIEELKSERDTLLARIERMERRMQLVKRDNEKERH---------KLLQGYEPEEREEAELSEKIKLERQPELCETSQALPSKPFSCGRSGKGH------------KRKTPFGNTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSISETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSE--------------------------------MEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSV----------------------------------------------------------------------------------------AGETSVLAVPSWRDHSVEPLRDPNPSDILENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKG--IQESEPEVTSFFPEPDDVESLLITPFLPVVAFGRPLPKLAP-QNFELPWLD------------------------------ERSRCRLEIQKKHTPHRTCRK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68DK7-1", "uniprot_id": "MSL1_HUMAN", "id": "Q68DK7-1", "name": "Male-specific lethal 1 homolog", "aln": "-------------------------------------------------------------------------------------------------MTMRSAVFKAAAAPAGGNPEQRLDYERAAALGGPEDEPGAAEAHFLPRHRKLKEPGPPLASSQGG------------------------------------------------SPAPSPAGCGG-KGRGLLLPAGAAPGQQ--EESWGGSVPLPCPPPATKQAGIG---GEPAAAGAGCSPRPKYQAVLPIQ---------------------------------------------------------TGS-LVAAAKEPTPWAGDKGGAASPAATASDPAGPPP-------------------------------LPLPGPPPLAPTATAGTLAASEGRWKSMRKSPLGGGGGS----------GASSQAACLKQILLLQLDLIEQQQQQLQAKEK--EIEELKSERDTLLARIERMERRMQLVKKDNEKERH---------KLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGH------------KRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSE--------------------------------IEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSV----------------------------------------------------------------------------------------AGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKG--IQESEPEVTSFFPEPDDVESLMITPFLPVVAFGRPLPKLTP-QNFELPWLD------------------------------ERSRCRLEIQKKQTPHRTCRK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QMZ2-1", "uniprot_id": "A0A8M9QMZ2_DANRE", "id": "A0A8M9QMZ2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------MNMRPECFSKAGLYS-----KKCDFSPSQTR------------HPVSVQRELRDP---LCDTPDD------------------------------------------------TREHLIS---QKNLERASLPSKPGRELI--VASEAGSVGTETLSSQAKQMGGE---GTPVKS------KTPFGQTNAID---------------------------------------------------------NKPEFVSMNSHIN---------------SRDPVGE----------------------------------------KNAKETMGSSHEHSEGKRTNMKK--ISGN--------------PHAQATCLKQLLLLQLDLIEQQQQQLQSKDK--EIDELKSDRDTLLARIERMERRLQLLSK--EPRDK---------RLFQPLERWVPDTDDFWES-------DLGDSPQTQASK-----SSGKVQ------------KRK--LSATETKT---------QRSRGKSSRTTPQKSDTRG---PSPCQRELRSKETPEKASTGKSSRK---------TDQHAEEGSSKE--------------------------------ADELPYMTTTEMYLCCWEPPDSS---LQEDCPKKEEDVASKFLVQIQNA------------------------------------------------------------------------------LFKRWFTNCYVKTIFPVPSWRENIMEPLKEEDAADLPESLDDSVFLKRHAKLELDEKRRKRWDIQRIREQRMLQRLQQRMEKKKPNVVQESEPEVSSFHPDLENVEAIMVTPFLPVVAFGRPLPNLTP-QNFELPWLD------------------------------EKSKGRVESQKKQTPHRTCRK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A9JRX0-1", "uniprot_id": "MSL1_DANRE", "id": "A9JRX0-1", "name": "Male-specific lethal 1-like 1", "aln": "-------------------------------------------------------------------------------------------------MTLRSIVIKSGGHRLD----TSLIKKPAEIN-----------EYLASLKKETCDFATYVLCSICN------------------------------------------------SIIQKHQVQSKAKISCRKVLSCPDQSSAGGLGHKNWEPSGALILPSTKQMGAE---GSPVKS------RSLFCQTNHNH---------------------------------------------------------LVN-MDPMVSNDN---------------NQQREGEQ---------------------------------------VGAMVGDSSPEDSPSGKHWNVRK---GSG-------------LVDPQTSCIRQILLLQLELIEQQQKHLHNKNK--EIEDLKAEKEMLMARIERMEHRLQMVKKDGVVSRP---------SQTTCHKEPEAETTTSDDV--------QHSGGRVQTPKQTQRGRGVKGS------------KGKFLLQDSPT-----------GRSRRGQPRSPPTSQ-----------------QESP-----------------------ALKEDMQCH--------------------------------SKEVPYLTTTEMYLSHWQTPPSP---QRDPSTVHENTVE--------------------------------------------------------------------------------------------------------VPSWRESILEPLGQKEASDILECLDDSVFLKRHSKLELDEKRRKRWDIQRIREQRMFQRLQQRMNRRKV--IQESEPELLSFHAEPEDVEYIMVTPFLPVVAFGSPLPNLKQ-QDFDLPWLD------------------------------ERSRCQPEVTKKRTPRRRCRK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50535-1", "uniprot_id": "MSL1_DROME", "id": "P50535-1", "name": "Protein male-specific lethal-1", "aln": "MDKRFKWPPKKRANYLESPYPHIPSRGRQRNLHGHPNQTQHLHQHPGKIYERQQYGNGRGGHGGGNNNYRKLLHSLPAEHGGGAMAPPSSGGTVCAGADMVKLISENNNLRRMVMLNLNLMQEQTDSIAAKDKELDDQSAKMSVVKAQNEELKQAVAQLEAANQELCKQLRRKNQRRNDNDDDDDDPPLPPAAPQQKLIRCHAETQTVFREREQGTQTIDAQPQFANALPRGINMKESPALDHHAGAVTNQPASKRSESKGRGEFNGKKVSTFILQRMNQDFEHHIHEQTEVAEEHEMEAHKEQISQEEDQLVAEEDHLHMQEVHTEEVVGGDIFHDALESIEMEVVTEELVDMEEHGQSVDANGHIEEDDDEDDEDDENSDKDDDSEEDDYPWMHSDADVNARTEEELWQNQNYLLELDPTEEKTCAPSAHSTPNHQQKSSTQAEIRKEGNQNRITEKLLQLKPEPMVDALEAPILPKWVAFKKKDKEHESVPESPEVPKQQPHQEDAIVDHNAIKNQLEVPKPDLKPKDQPKDEQRQDGQLDVRVEPQEDVRKVQKETLKRQPEDAPKHLPKAVAPKVTKTSSRESTLPKANTADIKDAPAQKVIANHQSTKTQTDPVKTQRLQVKIRQYEMHPDMRTGSSAPSDIRKQKNVDPVSTPETKTIKSKSMLVNDKKTTSETSQSPDQEIDVETVRRKLAEHLKKELLSQSHSSQVTLKKIRERVATNLIYPPPSAPVSSTTITPAPTPSTTPTPGSTPQHAVTSSMDQEISAAKSKSKAAEQIATPLTPQSNSSVSSTTSTIRKTLNNCSPHTYSKATARSGKLQSRFRTATFPYSTRTWEDQEFHCDNEFFLEEADELLADNPSLEIPKWRDVPVPPSSDKIDTELLS---DATFERRHQKYVKDEVDRKCRDARYMKEQIRLEQLRMRRNQDEVL-VALDPLRASTFYPLPEDIEAIQFVNEVTVQAFGENVVNMEARDDFGVPWVDAIEAPTSIARSKALAEPVATLASKKIPTTAAEARHQENHSSYVFPKRRKRQKNR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : : : : : ::. * * . : . : . . .. : . .. .. : . : . . .:. :* : ::::::. . : *: . :..:: :. : ::.:::: . : : :. ..* . * : : . * .:* .: . . :: * ..: . * .. . :. * :*.**: : * : ::: . *:.* :** * ** ** * : ::** :::*: * : : : . . :*.. :::* : .. :.* *** : :: ::* :**:* .:: : : . *:* *: ", "identical_positions": 42, "similar_positions": 140, "identity": "4.03%" }, { "cls_id": "homologset.agr.FB:FBgn0005619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16453-1", "uniprot_id": "DCHS_RAT", "id": "P16453-1", "name": "Histidine decarboxylase", "aln": "MMEPSEYHEY----QARGKEMVDYICQYLSTVRERQVTPNVKPGYLRAQIPSSAPEEPDSWDSIFGDIEQIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPDFFLHHHPSSQGGGVLQRTVSESTLIALLAARKNKILEMK--AHEPNADESSLNARLVAYASDQAHSSVEKAGLISLVKIKFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDKLSELGPICAREGLWLHVDAAYAGTAFLRPELRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTDMAKYFESLVRSDPVFEIPAERHLGLVVFRLKGPNCLTESVLKEIAKTGQVFLIPATIQDKLIIRFTVTSQFTTKDDILRDWNLIREAANLVLSQHCTSQP--------------------------SPRAKN-----------------------------------------------------LIPPPVTRDSKDLTNGLSLESVNEGGDDPVQVRKIFRLP------------GDSLETTMDPFDDCFSEEASDTTKHKLSSFLFSYLSVQNKK----KTMRSLSCNSMPMSAQKSPPPDASVKHG-------------GFFRARIFSGFPEEMMMMKKGGFKKLIKFYSVP---------------------------------------SFPECSSQCGTLQLPCCPLQAMV------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23738-1", "uniprot_id": "DCHS_MOUSE", "id": "P23738-1", "name": "Histidine decarboxylase", "aln": "MMEPCEYREYREYYRARGKEMVDYISQYLSTVRERQVTPNVQPGYLRAQLPASAPEEPDSWDSIFGDIERVIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPEYFLHHHPSSRGGGVLQSTVSESTLIALLAARKNKILAMK--ACEPDANESSLNARLVAYTSDQAHSSVEKAGLISLVKIRFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDRLSELGPICASEGLWLHVDAAYAGTAFLCPELRGFLEGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGAATDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRSDPSFEIPAKRHLGLVVFRLKGPNCLTESVLKEIAKAGQLFLIPATIQDKLIIRFTVTSQFTTKEDILRDWHLIQEAANLVLSQHCTSQP--------------------------SPRAKN-----------------------------------------------------VIPPPPG------TRGLSLESVSEGGDDPAQARKIIKQPG---ASLARREGGSDLETMPDPFDDCFSEEAPNTTKHKLSSFLFSYLSVQNRR----KTTRSLSCNSVPMSAQKSLPADASLKNG-------------GSFRARIFSGFPEQMMMMKKGAFKKLIKFYSVP---------------------------------------SFPECSSQC-ARQLPCCPLEAMV------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19113-1", "uniprot_id": "DCHS_HUMAN", "id": "P19113-1", "name": "Histidine decarboxylase", "aln": "MMEPEEYRER-------GREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGDIERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMK--TSEPDADESCLNARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSVKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNCLTENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLILSQHCTSQP--------------------------SPRVGN-----------------------------------------------------LISQIRG--ARAWACGTSLQSVSGAGDDPVQARKIIKQPQRVGAGPMKRENGLHLETLLDPVDDCFSEEAPDATKHKLSSFLFSYLSVQTKK----KTVRSLSCNSVPVSAQKPLPTEASVKNG-------------GSSRVRIFSRFPEDMMMLKKSAFKKLIKFYSVP---------------------------------------SFPECSSQC-GLQLPCCPLQAMV------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH77-1", "uniprot_id": "A0A8M2BH77_DANRE", "id": "A0A8M2BH77-1", "name": "Histidine decarboxylase", "aln": "-MQPQEYMLR-------GKEMVEYIHQYLTGIRERRVVPDVQPGFMRPLLPSSAPYEPEDWSTIMQDVENIIMPGVVHWQSPHMHAYFPALNSWPSLLGDMLADAINCLGFTWASSPACTELEMCVLDWLCKALGLPDHYLHHHPQSTGGGILQSTVSECTLVALLAARKDRILQMKSEATHTDTDESVLNSRLVAYASDQAHSSVEKAGLISLVKIRFLQTDAVFSLRGETLQRAVEEDRRSGLIPVMVCATLGSTGVCSFDRLDELGPVCVREGLWLHVDAAYAGSALLCPELRYFLDGIQFADSFVFNPSKWMLVHFDCTAFWVKNKMKLQQTFTVDPLYLRHDNS-NATDFMHWQIPLSRRFRSLKLWFVIRSFGLKKLQEHIRHGVEMAKLFESLVRNDTHFQIPAQRHLGLVVFCLRAGNAATQELLRKLTRSGRMFLIPAAVGNQLILRFSVTSQLTTEQDIRRDWSLIQQAAREVLQSGVVTRQ--------------------------PSVTSD-----------------------------------------------------PESEPES---------LTIH------TEPMLDQRLVRQGQ--------------RRAVRSYSCSAELPPAPGRTQTHRDAPLQLIPEQPERP----QHRRLLKFNSVPSLAQ-----------------------------VWAQCGMQQLHHPFRRGLITSRASCFTCP---------------------------------------PLPEG-----------TPLPTK-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05733-1", "uniprot_id": "DCHS_DROME", "id": "Q05733-1", "name": "Histidine decarboxylase", "aln": "-MDFKEYRQR-------GKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFH--ERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDDIVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFAAIFDADEFLAKTYAGVRIAHQESPSMRRRVRGILMSGKQFSLDSHMDVVVQTTLDAGNGATRTSTTNSYGHTTSAAQANSERQASIQEDNEESPEETELLSLCRTSNVPSPEHAHSLSTPSRSCSSSSHSLIHSLTQSSPRSSPVNQFRPITLCAVPSQSQLSMPLAMPLPNRNVTVSVDSLLNPVTTCNVYHGKRFLEPLENLAQTSASFSSSIFRLPTPIATPTRESPEDPDWPAKTFSQLLLERYSSQSQSLGNNSSTESSSLSGGATPTPTPMSSLDELVTPLLLSFASPSQPMLSAHGIGEGQREQGSDSDATVCSTTSSMESL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** *:***:** :** :***:* *:*.**::* :* *** : : * .*: *:*.::***:.**********:***.* *****************************: :::** * :***: :** ..* ***:** *.**.**:.***.*. * :: ... ::: :*:***** ***********.**.**::::: .* :::**: *:.*:*:* : **:*. ******:** *:** *.*:* :*. . ****:******:*:: **:* :* **: ***:.******::****.*.:**::. :::**.*:*:**:* ** *.**************::*:***:**:*:* ** *:*.*. :*: **:** * *::**:******** ::. * *:.:*:.: : *.:. **::: .: ::**::** ** :** :** *::.* :*.. : .. . : . . :. :: : . :.. : . * : * :. ::* :* . : : : : . . : * . .* *: : ", "identical_positions": 257, "similar_positions": 181, "identity": "29.99%" }, { "cls_id": "homologset.agr.FB:FBgn0005624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LP49-1", "uniprot_id": "A0ABK0LP49_RAT", "id": "A0ABK0LP49-1", "name": "Polycomb group RING finger protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTQIKIMELNPHLMCALYGGYFIDTTTIVECLHSFCKTFIVRYLETNKYCPMCDVQVHKTGPLLSIRSDKTLQDIVYKLVSGLFKDVMKGRRDFYAAYPLTEVPNGSNNDHVEILKQEKGALGDNEIVSLSIKLYR-----EAKKSLVENGDEDKEKTGVLFLRCPAVMTFMHLAKFLCNEMDVPSK-YKVEILYEDK--PLKEYYTLMDIAYIYPWQRNGPLPLKYRVQP-------ACKRLTLPTVPTPSEGTNTSGP--------PSQAPSPAT-------------------------------------------------------LPATSSSLSSPGTPSHGSPSSHS-------------------PAATHLTSPTPPSTAAVTTTATNGGTSNCLQMPSSTSRGCKMSVNGAPCPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23798-1", "uniprot_id": "PCGF2_MOUSE", "id": "P23798-1", "name": "Polycomb group RING finger protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKNLTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSK-YKVEILYEDE--PLKEYYTLMDIAYIYPWRRNGPLPLKYRVQP-------ACKRLTLPTVPTPSEGTNTSGAS--ECESVSDKAPSPAT-------------------------------------------------------LPATSSSLPSPATPSHGSPSSHG-------------------PPATHPTSPTPPSTAAGTTTATNGGTSNCLQTPSSTSRGRKMTVNGAPCPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35227-1", "uniprot_id": "PCGF2_HUMAN", "id": "P35227-1", "name": "Polycomb group RING finger protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSK-YKVEVLYEDE--PLKEYYTLMDIAYIYPWRRNGPLPLKYRVQP-------ACKRLTLATVPTPSEGTNTSGAS--ECESVSDKAPSPAT-------------------------------------------------------LPATSSSLPSPATPSHGSPSSHG-------------------PPATHPTSPTPPSTASGATTAANGGSLNCLQTPSSTSRGRKMTVNGAPVPPLT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35226-1", "uniprot_id": "BMI1_HUMAN", "id": "P35226-1", "name": "Polycomb complex protein BMI-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFD--QNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNT-FQIDVMYEEE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRP-------TCKRMKIS---HQRDGLTNAGE--LESDSGSDKANSPAGG------------------------------------------------------IPSTSSCLPSPSTPVQ---SPH--------------------PQFPHISSTMNGTSNSPSGNHQ----------SSFANRPRKSSVNGSSATSSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25916-1", "uniprot_id": "BMI1_MOUSE", "id": "P25916-1", "name": "Polycomb complex protein BMI-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEEKRIITDDEIISLSIEFFD--QSRLDRKVNK--EKPKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNT-FQIDVMYEEE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRP-------TCKRMKMS---HQRDGLTNAGE--LESDSGSDKANSPAGG------------------------------------------------------VPSTSSCLPSPSTPVQ---SPH--------------------PQFPHISSTMNGTSNSPSANHQ----------SSFASRPRKSSLNGSSATSSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNP3-1", "uniprot_id": "A0ABZ3NNP3_RAT", "id": "A0ABZ3NNP3-1", "name": "Polycomb complex protein BMI-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELRVFYQAEMHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDRRVIADDEIISLSIEFFH--PSRSDRKVTK--EKPKEEVNDKRYLRCPAALTVMHLRKFLRSKMDIPNT-FQIDVMYEEE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRP-------TCKRMKMS---QQRDGLTAAGE--LESDSGSDKANSPAGG------------------------------------------------------APSTSSCLPSPSTPVQ---SPH--------------------PQFPHISSTMNGTSNSPSGNHQ----------SSFASRPRKSSVNGSSATSSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JIR0-1", "uniprot_id": "BMI1A_DANRE", "id": "Q8JIR0-1", "name": "Polycomb complex protein BMI-1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKMCIVRYLETSKYCPICDVQVHKTKPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHPSVDAANGSNEDRGEVADEDKRIITDDEIISLSIEFFD--HRAQQQGCTE--ERQKEEVNNKRYLQCPAAMTVMHLRKFLRSKMDIPPT-YQIEVMYEDE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRP-------SCKKMKIT---HPQEGLNNANR--SESDSASDKACSPAG-------------------------------------------------------VPSTSSPLPSPSTLVQ---PSQ--------------------PHFTHISSPINGTTMT-SPNRQ----------FNFS-KVRKSALNGS-STSSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T3E6-1", "uniprot_id": "BMI1B_DANRE", "id": "Q7T3E6-1", "name": "Polycomb complex protein BMI-1-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTRIKITELNPHLMCVLCGGYFIDATTIVECLHSFCKMCIVRYLETSKYCPICDVQVHKTKPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHP-VDATNGSNEDRGEVSDEDKRIIADDEIISLSIEFFD--QKKLDGKDGEE-KESTKEVTVKRYLQCPAAMTVMHLRKFLRSKMDIPCT-FQIEVMYEDE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRP-------GCKKIKLS---SPRNDMSGGRRPDTESDSSSDKPNSPSIVA-----------------------------------------------------APSTSSSMPSPNTPVQ---STH--------------------PSFPHIS-TINGVSAKVGHNGQ----------TPFSSKVCKTSHNGSNSLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35820-1", "uniprot_id": "PSC_DROME", "id": "P35820-1", "name": "Polycomb group protein Psc", "aln": "MMTPESKAIQPAAATTKQTAEATATTTMAHTQQKSQLSTLAKTTTTTATNKAAKSVVSNANSSGNNSSKKLALSQSQKTTTTTTPPTTTTTTTAAAAAEATTNADKMQKQQQLKQQLFAACSIKVKSENTLATTANAALAAATTTTTTATPALATGKAAKTILENGIKKESTPPAVESVEASSSSSSSSSSSSSSSSSWPTTRRATSEDASSNGGASADEEKSEEDPTAAVAASSTATTTSDLATTSRPRPVLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINNAKP--NIKSDTTLQAIVYKLVPGLYERELMRKRAFYKDRP-EEAALATPEQRGDDTEHLIFSPSDDMSLSLEYAELG--------ELKTDSEPELVDTLRPRYLQCPAMCRVSHLKKFVYDKFEIDAQRFSIDIMYKVKTIVLLDYYTLMDIAYIYTWKRDAPMRFYYRVYESPQPLVKPAPRRVLPLKLEKQERENQEQQLAVEVASSKVEPVSLPEDQKAEASIKVEEQESTREIVKEVIKDVAATPPTETLKLVINRNMLDKREKSHSPQMSSKSSSKSSPCTPVSSPSEPNIKLKIDLSKQNSVTIIDMSDPERREIVKPLKPEKESRSKKKDKDGSPKSSSSSSSSSSGERKRKSPSPLTVPPLTIRTERIMSPSGVSTLSPRVTSGAFSEDPKSEFLKSFALKPIKVKVESPERTLNNRAITPPSPSVQQSASPKSKGNNLDDSILMKPPSCMPPKSIASSKRKSKEPVKAVSKKQKLSPPLPTVDFKIRLPVTNGNSSGTASPKIEKPLMPPPAKPPMLAPRKLQPSAQFAPPPSPIHHHAGVQMSAPGNRTPIAKRYQPILPKASRPNPFANIPNDVNRLLKDAGTEIKSIGGGSVENNSNAAQKPHLYGPKGESKMGPPALPATTPSQGNKNVGKQAGNLPMSAPPNKGNSSNNYLNLALFNSSKCKGKEAPPGCRTPMYTPNSPIYSPSSPQYVPSYNIPTMPTYKYTPKPTPNSGSGNGGSGSYLQNMLGGGNGGSLGGLFPSPPTKSDQNTNPAQGGGGSSSATQSGGNNGIVNNNIYMPNEDAPEKQQVKVKSLLNSCNINIPSSLSITISRDNGDSSSPNNGQHPKHKSPVNNYIEIVKLPDQPQDQVQAAKEAQKRQSPPAAVPGHLAAKLPPPPPSKAIPSPQHLVSRMTPPQLPKVATPPPPSSPRVITPPKTSPPANAAKVTPLKPVLTPTQVDKKTPSPEKRTAAQMGSHSPTASENKSPKGGPAGVANSTGGAQNGDPAAKKFRPILPRQNGMPELAPKLPTLAPFVGFNPLQNPAAGKKVPPSKKSPNAGAAAHQSGQQKLVNGGQSQPAQQKTSPPAQKNQQQVKKVSKNPTPPPPSLPAVGKMMPHPVMHSQNAPLSIASSASAAAVASGQLDLSNFLKENLRRVHAAQAAQAAQVAAAANQSNMMYNLAQMGHMTPAMYNYQQAYFREQLSRMQRVGNEVFNDYLQKLKTAAATGGGGPVEGELKPMLPTVTLPSPGATPPAASPKTSPLPAGKLTAAATAPQTKGNSSSGAANARQQTAATGNNGATVPAASLPPATKSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : :***::* * **:*::***:*******: ::.:*...::** *:: :::: * .*:**.*** ******.**:: : :* ** * :.. .: ::: : .. *: :**. : :*:*** . ** **: .:::: :.::::*: : * :***********.*:*:.*: : *** . : :. : . :. * . .:.** .** * .: * . . . . : : . : ", "identical_positions": 79, "similar_positions": 96, "identity": "4.9%" }, { "cls_id": "homologset.agr.FB:FBgn0005626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04177-1", "uniprot_id": "TY3H_RAT", "id": "P04177-1", "name": "Tyrosine 3-monooxygenase", "aln": "MPTPSAPSPQPKGFRRAVSEQDAKQAEAVT-------------------------------SPRFIGRRQSLIEDARKER-----EAAAAAAAAAVASS------------------EPGNPLEAVVFEE-RDGNAVLN---------------------LLFSLRGTKPS--------------------SLSRAVKVFETFEAKIHHLETRPAQRP-LAGSPHLEYFVRFEVPSGDLAALLSSVRRVS--DDVRSARED----KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKHGEPIPHVEYTAEEIATWKEVYVTLKGLYATHACREHLEGFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFNDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIQRSLEGVQDELHTLAHALSAIS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24529-1", "uniprot_id": "TY3H_MOUSE", "id": "P24529-1", "name": "Tyrosine 3-monooxygenase", "aln": "MPTPSASSPQPKGFRRAVSEQDTKQAEAVT-------------------------------SPRFIGRRQSLIEDARKER-----EAAAAAAAAAVASA------------------EPGNPLEAVVFEE-RDGNAVLN---------------------LLFSLRGTKPS--------------------SLSRALKVFETFEAKIHHLETRPAQRP-LAGSPHLEYFVRFEVPSGDLAALLSSVRRVS--DDVRSARED----KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGEPIPHVEYTKEEIATWKEVYATLKGLYATHACREHLEAFQLLERYCGYREDSIPQLEDVSHFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRRSLEGVQDELHTLTQALSAIS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07101-1", "uniprot_id": "TY3H_HUMAN", "id": "P07101-1", "name": "Tyrosine 3-monooxygenase", "aln": "MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGAPGPSLTGSPWPGTAAPAASYTPTPRSPRFIGRRQSLIEDARKER-----EAAVAAAAAAVPS-------------------EPGDPLEAVAFEE-KEGKAVLN---------------------LLFSPRATKPS--------------------ALSRAVKVFETFEAKIHHLETRPAQRP-RAGGPHLEYFVRLEVRRGDLAALLSGVRQVS--EDVRSPAGP----KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBY7-1", "uniprot_id": "A0A8M2BBY7_DANRE", "id": "A0A8M2BBY7-1", "name": "Tyrosine 3-monooxygenase", "aln": "MKSDSIAQNVP-----------------------------------------------------LSGRKRSLIEDARRDR-----ESGSSSPGPSRCG-------------------------DSFVFEEEKTGKITLN---------------------ILFALKNEKNA--------------------GFFKAGKVFETFETKLLHLESRASRKSKRSSGEDLEFFMRCEVHCSDTDIFINSLKRVA--DDVRIVQEE----KTPWFPKKISDLDTCNHLITKYDPDLDQDHPGFSDSEYRKRRGFISEMAFNYKHGDPLPVVEYTPEENATWREVYRTLRSLYPSHACRQFLEALTQLESERLYGEDQIPQLREVSAFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHPSAPMHSPEPDCCHELLGHIPMLADQEFAQFSQEIGLVSLGASDEDIEKLSTLYWFTVEFGLCKQNGAVKAYGAGLLSSYGELLYALSNEPQYKPFDPAETAVQPYQDQSYQPVYFVSESFEDAKQKLRRYSSTIQTPFSIRYDPYTCSMEVLDEPSKIQNALGQMRDDLKILHKALGRLGQK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18459-1", "uniprot_id": "TY3H_DROME", "id": "P18459-1", "name": "Tyrosine 3-monooxygenase", "aln": "MMAVAAAQKNREMFAIKKSYSIENGYPSRR---------------------RSLVDDARFETLVVKQTKQTVLEEARSKANDDSLEDCIVQAQEHIPSEQDVELQDEHANLENLPLEEYVPVEEDVEFESVEQEQSESQSQEPEGNQQPTKNDYGLTEDEILLANAASESSDAEAAMQSAALVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVE----GVDHDVLIKLDMTRGNLLQLIRSLRQSGSFSSMNLMADNNLNVKAPWFPKHASELDNCNHLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFKTVQDLAPKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRKNTGFSLRPAAGLLTARDFLASLAFRIFQSTQYVRHVNSPYHTPEPDSIHELLGHMPLLADPSFAQFSQEIGLASLGASDEEIEKLSTVYWFTVEFGLCKEHGQIKAYGAGLLSSYGELLHAISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLVHQMNTEILHLTNAISKLRRPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . :::::*:** . * . . : . **. . : : :*:: : : .: : *.:***. .: *:*:* :: . . : ::: :: .: :: .::: . ..:. *.****:: *:**.*:**:**::**** :****:*. **:** *:*:** *: *:*:* ::*: * **:.*: *::.* ..*** :. .: *: : * :***.::* **::.***.***.****:***********:**.***:** .:* *:****. ******:*:*** ******:***.*******:******:***********::* :***************:.:*:: : :.*:* :******** **.:*:*:***.***:*:* : * :. **.::::*:* ::***. :. : :. :: * :*:. : ", "identical_positions": 193, "similar_positions": 157, "identity": "31.95%" }, { "cls_id": "homologset.agr.FB:FBgn0005631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCL0-1", "uniprot_id": "A0ABK0LCL0_RAT", "id": "A0ABK0LCL0-1", "name": "", "aln": "-----MTPLMFTLLLLFGFLC-------------------------------------------------IRTDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGTYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDEKEER--------ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEDEPAEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDD-YTLRIKKAISADEGTYVCIAENRVGKVEASATLTVR----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDPRATIQDQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATIS--KNYDTNDLPGPPSKPQVTDVTKNSVTLSWQPGT--PGV-LPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD-VTVRLHNPVVLTPTTVQVTWTVDR--QPQFIQGYRVMYRQTSGLQAS-TVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTIRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIWCLGNET--RFHINKTVDATIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRN--EVVIT-----ENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSN--------------YAVTFQRGDGGLMSNGSRPGLLNTGDPS-YPWLADSWPATS--LPVNNS--NSGPNEIGNFGRGDFKHNVNKNLAEHGIKKEFLGMERNKNDVLPPVPGQGDKTAT--MLSDGAIYSSIDFTTKT----TYNSSSQIT--------QATPYATTQILHSNSIHELAVDLP------------DPQWKS----SVQQKSDLMGFAYSLPDQNKGNNG------------------------------------GKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYPAEQ-ENGYDSDSWCPPLPVQTYLHQGMEDELEEDED-----RVPTPPVRGVASSP-AISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYASGALISDLE----TDVPDEDADDEEEPLEIPR-------------------PLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLT---------RTGKAFTSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQP---VLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVESSTERKGSSLERQQ-------------AANLEDTKSSLDCPAKTTVEWQHQTQDWINSTERQEETRKAPHKPGVGSEESLVPYSKPSFPSPG------GHSSSGTASSKGSTGPRKAEILRGSHQRNANDLLDIGYVGSNSQGQFTE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPD3-1", "uniprot_id": "ROBO2_MOUSE", "id": "Q7TPD3-1", "name": "Roundabout homolog 2", "aln": "-----MNPLMFTLLLLFGFLC-------------------------------------------------IQIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER--------ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDD-YTLRIKKAMSTDEGTYVCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDPRATIQDQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATIS--KNYDMNDLPGPPSKPQVTDVSKNSVTLSWQPGT--PGV-LPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD-VVVRLHNPVVLTPTTVQVTWTVDR--QPQFIQGYRVMYRQTSGLQAS-TVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIWCLGNET--RFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRN--EVVIT-----ENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSN--------------YAVTFQRGDGGLMSNGSRPGLLNAGDPN-YPWLADSWPATS--LPVNNS--NSGPNEIGNFGRG---------------------------DVLPPVPGQGDKTAT--MLSDGAIYSSIDFTTKT----TYNSSSQIT--------QATPYATTQILHSNSIHELAVDLP------------DPQWKS----SVQQKTDLMGFGYSLPDQNKGNNG------------------------------------GKGGKKKKTKNSSKAQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQ-ENGYDSDSWCPPLPVQTYLHQGMEDELEEDED-----RVPTPPVRGVASSP-AISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPAPPLGYVSGALISDLE----TDVPDEDADDEEEPLEIPR-------------------PLRALDQTPGSSMDNLDSSVTG----------------------------------------------------------------------KAFSSSQRQRPTSPFSTDSNTSAAQNQSQRPRPTKKHKGGRMDPQP---VLPHRREGMPDDLPPPPDPPPGQGLRQQIGLSQHSGNVENSTERKGSSLERQQ-------------AANLEDTKSSLDCPAKTVLEWQRQTQDWINSTERQEETRKAPHKQGVGSEESLVPYSKPSFPSPG------GHSSSGTSSSKGSTGPRKADVLRGSHQRNANDLLDIGYVGSNSQGQFTE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCK4-1", "uniprot_id": "ROBO2_HUMAN", "id": "Q9HCK4-1", "name": "Roundabout homolog 2", "aln": "-----MSLLMFTQLLLCGFLY-------------------------------------------------VRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER--------ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATIS--KNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGT--PGT-LPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD-VLVRLHNPVVLTPTTVQVTWTVDR--QPQFIQGYRVMYRQTSGLQAT-SSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNET--RFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRN--EVVIT-----ENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSN--------------YAVTFQRGDGGLMSNGSRPGLLNAGDPS-YPWLADSWPATS--LPVNNS--NSGPNEIGNFGRG---------------------------DVLPPVPGQGDKTAT--MLSDGAIYSSIDFTTKT----SYNSSSQIT--------QATPYATTQILHSNSIHELAVDLP------------DPQWKS----SIQQKTDLMGFGYSLPDQNKGNNG------------------------------------GKGGKKKKNKNSSKPQKNNGSTWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDD-----RVPTPPVRGVASSP-AISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPPLGYVSGALISDLE----TDVADDDADDEEEALEIPR-------------------PLRALDQTPGSSMDNLDSSVTG----------------------------------------------------------------------KAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQP---ALPHRREGMTD--------------------------------------------------------------------------------------------------------EEALVPYSKPSFPSPG------GHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTGEL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55005-1", "uniprot_id": "ROBO1_RAT", "id": "O55005-1", "name": "Roundabout homolog 1", "aln": "MKWKHLPLLVMISLLTLSKKH------LLLAQLIPDPEDLERGNDNGTPA-----------PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESKVADVTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTFGWRKDDGELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ----EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTVTNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLTLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLLWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTTQGVDHKQVQRELGN-VVLHLHNPTILSSSSVEVHWTVDQ--QSQYIQGYKILYRPSGASHGE-SEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEERPSAPPRSVTVSKND-GNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNET--RYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHG--NPVSP-----EDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSTYAGIRKVPSFTFTPTVTYQRG-GEAVSSGGRPGLLNISEPATQPWLADTWPNTG--NSHNDCSINCCTASNGNSDSN-------------------LTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQANLINN-MNNGGGDSS--------EKHWKP----PGQQKQEVAPIQYNIMEQNKLNKD-YRANDTILPTIPYNHSYDQNTGGSYNSSDRGSSTSGSQGHKKGAR-TPKAPKQGGMNWADL-LPPPPAHPPPHSNSEEYSMSV-DESYDQEMPCPVPPARMYLQQ---DELEEEEA----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEED--EADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEED-NISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAV--IQKARPTKKQK-----HQP----GHLRREAYTDDLPPPPVPPPAIK-SPSVQSKAQLEA-RPIMGPKLASIEARADRSSDRKGGSYKGREALDGRQVTDLRTSPGDPREAQEQPNEGKARGTKTAKRDLPPAKTHLIPEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89026-1", "uniprot_id": "ROBO1_MOUSE", "id": "O89026-1", "name": "Roundabout homolog 1", "aln": "--------------MIAEPAH------FYLFGLIC------------------------------------LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ----EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLILSCVATGSPAPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGN-VVLHLHNPTILSSSSVEVHWTVDQ--QSQYIQGYKILYRPSGASHGE-SEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKND-GNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNET--KYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHG--NPVSP-----EDQVSLAQQISDVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRG-GEAVSSGGRPGLLNISEPATQPWLADTWPNTG--NNHNDCSINCCTAGNGNSDSN-------------------LTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQANLSNN-MNNGAGDSS--------EKHWKP----PGQQKPEVAPIQYNIMEQNKLNKD-YRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGAR-TPKAPKQGGMNWADL-LPPPPAHPPPHSNSEEYNMSV-DESYDQEMPCPVPPAPMYLQQ---DELQEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEED--EADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEED-NISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAVV--IQKARPAKKQK-----HQP----GHLRREAYADDLPPPPVPPPAIK-SPTVQSKAQLEV-RPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVTDLRTNPSDPREAQEQPNDGKGRGTRQPKRDLPPAKTHLGQEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6N7-1", "uniprot_id": "ROBO1_HUMAN", "id": "Q9Y6N7-1", "name": "Roundabout homolog 1", "aln": "MKWKHVPFLVMISLLSLSPNH------LFLAQLIPDPEDVERGNDHGTPI-----------PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ----EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN-AVLHLHNPTVLSSSSIEVHWTVDQ--QSQYIQGYKILYRPSGANHGE-SDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKND-GNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNET--RYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHG--NPVSP-----EDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRG-GEAVSSGGRPGLLNISEPAAQPWLADTWPNTG--NNHNDCSISCCTAGNGNSDSN-------------------LTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNN-MNNGSGDSG--------EKHWKP----LGQQKQEVAPVQYNIVEQNKLNKD-YRANDTVPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGAR-TPKVPKQGGMNWADL-LPPPPAHPPPHSNSEEYNISV-DESYDQEMPCPVPPARMYLQQ---DELEEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEED--EADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEED-NISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAV--MQKTRPAKKLK-----HQP----GHLRRETYTDDLPPPPVPPPAIK-SPTAQSKTQLEV-RPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQNDGKGRGNKAAKRDLPPAKTHLIQEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYERGEDNNEELEETES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T813-1", "uniprot_id": "A0AB32T813_DANRE", "id": "A0AB32T813-1", "name": "", "aln": "MEFIPLVVSILAMLVMMGVQHGGTPGVPRHASLRNQPNQWCKRPHGSFLVGAHHRPTQQRHHNSKKHKCFQDFQRSRLRQEDYAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRDDFRQNPVDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNIDDRDER--------ITIRGGKLMITNTRKTDAGKYVCVGTNMMGERESEIAELTVLERPSFLRKPSSQSVLVDQSVEFRCEAQGDPVPTIRWRKEDGELPKGRYEIWED-HTLKLKRLTSGDAGTYTCQAENMMGKTEASATLTVH----VPPVFVVRPRNQVAGMGRTVTFQCEATGSPQPAIFWQKEGSQNLLFSSQPPPPSSRFSVSQTGDLTITAVERSDGGYYSCQALNIAGSVITKALLEVTDVISDRPPPIVRQGPTNQTVAVDGTVVLSCQATGTPIPTILWRKDGVLVSTHDSRLKQLDTGALQIRYAKLGDTGMYTCTASTPSGEASWKAYLEVQEFGAPVQPGRPTDPNLIPSAPSKPDVTDVSRTSVSLSWKPNL--NAG-ATPTSYVIEAFSHAAGSSWQTLADHVKTESFVLKGLKPSAVYLFLVRAANAYGLSDPSPISDAVKTQDVPPTSQGVEHGQIQRELGD-VVIHLHNPTILSSSSVRVQWTVEQ--QSQYIQGYKVMYRPSPEGAPQRVDWAMFEVGAPGEHSAVVTQLKKGITYEFKVRPFFNEFQGTDSDIKVGKTLEEAPSAAPRGVTVTGSG-DNGTAVLVAWQPPPEEEQNGVVQEYKIWCLGNES--RYHINRTVDGSTHSVLIPGLVAGVTYRLEVAAGTGAGPGVKSDPTSFQLDSSG--RVLPPP---LDDDNTISQQISDVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSSYAGIRKVPSFTFTPTVAYQRG-GEAVSSAGRPGLLNIGEPATQPWLADTWPNSC--SNHNDCTINCCTGSNGNSDSN-------------------LATYSRPADCIANYSNQMDNKATNLLAPDTGLYSDVDLSNKINEMKTFNSPNLKDGRFMGPGGQPTPYATTQLIQSSLANNNMNSSSGGSGGGSADFNEKQSWKSSQGTPQKQADINTPLQYNVMEQNKLNKDHYRGEGPISVTIPYNQAQDVLTGETYSSSDRGSSTSGSQGQKKGGR-TTKQAKQNPMNWTEL-LPPPPVNPPP---CQEYTLVM-DDSYDTDLQCPLPPSRMYLQP---DELEEEEDEVELERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEEMHPMLQDNPD-------LHERRRLLVSPPPPPRPLSPPHTYGYISSPLGLDTDGLEEEDDDEEEGD--ETDAEVARVHQHHMMHPHQQHLPQQRALLRGLEQTPASSTCDLESSVTGSMINGWGSASEED-NASSGRSSAVSSSDGSFFTDADFAQAVAAAAEYAGLRVAKHPGKGHHQLPVSGAARKYQNLPAGHRPGSPVSTDSNVSAAP--GQR-RPLKRQK-----QHPAAQTGYQRREAYTEDLPPPPIPPPAMLKSPTHPAKTIPEGPRGAMSPRSSSADGKDRRTGAG------GPRVRDG---SDTRTSSSERRDGQDVQR-GQRTGKNSKQDEAVKSRQHPGSEDILPYSRPSFPAVHSPRGERDPSSSSSLSSRGSGGRRRGEGPPGARRNPADIGLNTIGAFQTGGDELEMVES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z2I4-3", "uniprot_id": "ROBO3_MOUSE", "id": "Q9Z2I4-3", "name": "Roundabout homolog 3", "aln": "MLRYLLKTLLQMNLFADSLARDISNSSELLFGFNSSLAALNPSLLP--------------------PGDPS-LNGSRVGPEDAMPRIVEQPPDLVVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGKIKLKEEEGR--------ITIRGGKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLHWRKDDGELPAGRYEIRSD-HSLWIDQVSSEDEGTYTCVAENSVGRAEASGSLSVHV----PPQFVTKPQNQTVAPGANVSFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPMGRLLVSPRGQLNITEVKIGDGGYYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNIQWKKDERWLQGDDSQFNLMDNGTLHIASIQEMDMGFYSCVAKSSIGEATWNSWLRKQED-WGASPGPATGPSNPPGPPSQPIVTEVTANSITLTWKPNP--QSG-ATATSYVIEAFSQAAGNTWRTVADGVQLETYTISGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRPAEDPWKGQRGLAE-VAVRMQEPTVLGPRTLQVSWTVDG--PVQLVQGFRVSWRIAGLDQGS---WTMLDLQSPHKQSTVLRGLPPGAQIQIKVQVQGQEGLGAESPFVTRSIPEEAPSGPPQGVAVALGGDRNSS-VTVSWEPPLPSQRNGVITEYQIWCLGNES--RFHLNRSAAGWARSVTFSGLLPGQIYRALVAAATSAGVGVASAPVLVQLPFP---PAAEPG---PEVSEGLAERLAKVLRKPAFLAGSSAACGALLLGFCAALYRRQKQRKELSHYTAS------FAYTPAVSFPHSEGLSGSS-SRP-PMGLGPAA-YPWLADSWPHPPRSPSAQEPRGSCCPSNPDPDDRY------------------------YNEAGISLYLAQTARGANA--SGEGPVYSTIDPVGEELQ--TFHGG----------------FPQHSS------------------------GDPSTWS----------------QYAPPEWSEGDSG------------------------------------ARGGQGKLLG---KPVQMPSLSWPEALPPPPPSCELS-CPEGPEEELKG--SSDLEEWCPPVPEKSHLVG----SSSSGAC-------MVAPAPRDTPSP-TSSYGQQSTATLTPSPPDPPQPPTD--IPHLHQMPR------------RVPLGPSSPLSV---SQPALSSHD-----GRPVG------------------------------------LGAGPVLSYHASPSPVPS---------------------------------------------------------------------------TASSAPGRTRQVTGEMTPPL-HGHRARIRKKP-----------KALPYRREHSPGDLPPPPLPPPEEETSWPLGLR-------------------------------------AAGSMSSLERERSGERRVVQAVPLGAQPLGAQRGPHPDAALLGCAAEEAWLPYGRPSFLSHGQGTS--TCSTAGSNSSRGSNSSRGSRGSRGPGRSRSRSRSQSQSQRPGRNRREEPR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJI9-1", "uniprot_id": "A0A8I6AJI9_RAT", "id": "A0A8I6AJI9-1", "name": "Roundabout homolog 3", "aln": "MLRYLLKTLLQMNLFADSLAGDITNSSELLFGFNSSLAALNPSLLP--------------------PGDPS-LNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGNTKLKEEEGR--------ITIRGGKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLRWRKDDGELPTGRYEIRSD-HSLWIEQVSAEDEGTYTCVAENSVGRAEASGSLSVHV----PPQFVTKPQNQTAAPGENVSFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPMGRLLVSPRGQLNITEVKIGDGGYYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNVQWKKDETWLQGDNSQFNLMDNGTLYIASVQEMDMGFYSCVAKSSIGEATWNSWLRKREH-WGASPGPATEPGNPPGPPSQPIVTEVTTNSITLTWKPNP--QSG-ARATSYVIEAFSQAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRPVEDPWKGQQGLAE-VAVRMQEPIVLGPRTLQVSWTVEG--PGQLVQGFRVSWRIAGLDQGS---WTALDVQSPHKQSTVLRGLPPGSQIQIKVQVQGQEGLGAESPSVTRSIPEEAPSGPPQGVAVALGGDRNSS-ITVSWEPPLPSQQNGVITEYQIWCLGNES--RFHLNRSAAGWARSVMFRGLLPGLLYRAIVAAATSAGVGVASAPVLVQLPFP---PVAEPG---PEVSEGLAERLSRVLRKPAFLAGSSAACGALLLGLCAALYRRQKQRKELSHYTAS------FAYTPAVSFPHSEGLSGSS-SRP-PMGLGPAA-YPWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRY------------------------YNEAGISLYLAQTARGANA--PGEGPVYSTIDPVGEELQ--TFHGG----------------FPQHSS------------------------GDPSTWS----------------QYAPPEWSEGDSG------------------------------------ARGGKGKLLG---KPVQMPSLSWPEALPPPPPSCELS-CPEGPEEELKG--SSDLEEWCPPMPEKKHLID----SRSSGAC-------MVAPARGETPSP-TSSYGQQSTATLTPSPPDPPQPPSD--IPHLHQMPR------------RVPLGPSSPLSV---SQPALSSHD-----GRPVG------------------------------------LGAGPIVSYHPSPSPVPS---------------------------------------------------------------------------TASSAPGRTRQVTGEMTPPL-HGHRARIRKKT-----------KALPHRREHSPGDLPPPPLPPPEEETSWPLGLR-------------------------------------AAGSMSSLEREHSGERRVAQAVPLGAQPPGAQRGPHPDAALLGCAAEEAWLPYGRPSFLSHGQGTS--TCSTAGSNSSRGSNSSRGSRGSRGPGRSRSR--SQSQSQRPGRNRRQEPR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96MS0-1", "uniprot_id": "ROBO3_HUMAN", "id": "Q96MS0-1", "name": "Roundabout homolog 3", "aln": "MLRYLLKTLLQMNLFADSLAGDISNSSELLLGFNSSLAALNHTLLP--------------------PGDPS-LNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGR--------ITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRSD-HSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHV----PPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRED-WGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNP--QTG-AAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSRPVEDPWRGQQGLAE-VAVRLQEPIVLGPRTLQVSWTVDG--PVQLVQGFRVSWRVAGPEGGS---WTMLDLQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSS-ITVSWEPPLPSQQNGVITEYQIWCLGNES--RFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPSP---PDLEPG---LEVGAGLAVRLARVLREPAFLAGSGAACGALLLGLCAALYWRRKQRKELSHYTAS------FAYTPAVSFPHSEGLSGAS-SRP-PMGLGPAP-YSWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRY------------------------YNEAGISLYLAQTARGTAA--PGEGPVYSTIDPAGEELQ--TFHGG----------------FPQHPS------------------------GDLGPWS----------------QYAPPEWSQGDSG------------------------------------AKGGKVKLLG---KPVQMPSLNWPEALPPPPPSCELS-CLEGPEEELEG--SSEPEEWCPPMPERSHLTE----PSSSGGC-------LVTPSRRETPSP-TPSYGQQSTATLTPSPPDPPQPPTD--MPHLHQMPR------------RVPLGPSSPLSV---SQPMLGIRE-----ARPAG------------------------------------LGAGPAASPHLSPSPAPS---------------------------------------------------------------------------TASSAPGRTWQGNGEMTPPL-QGPRARFRKKP-----------KALPYRRENSPGDLPPPPLPPPEEEASWALELR-------------------------------------AAGSMSSLERERSGERKAVQAVPLAAQ-----RVLHPD--------EEAWLPYSRPSFLSRGQGTS--TCSTAGSNSSRGSSSSRGS---RGPGRSRSRSQSRSQSQRPGQKRREEPR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJU1-1", "uniprot_id": "A0A8M2BJU1_DANRE", "id": "A0A8M2BJU1-1", "name": "", "aln": "MLRYLIKTLLQMNLFTDTIR-DATNGTDLFFNISS-IPSFNSSLLD--------------------WANFTGLNGSRPRLEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDER--------ITIRGGKLMISNTRKSDAGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEEGELPRGRFEIRAD-NSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVGPSLPPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGETSWSGVLTVKES-GGLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTWQPNA--HEGGAAVTSYIIEAFSQSAGSTWQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPISEPVRTQDVSPTGQGVDHRQVQRELGE-MSVQLHEPVLLTASSVKISWNVDR--QSQYIQGYRLLYRPVG---GS---WSQQEVKGATERSAVIANLLKGTEYEIKIRPYFNEFQGLDSRSQTLRTPEEVPSAPPRAVNVATVKLSNSSSISVSWQPPPTDMQNGVIQEYKVWCLGNDSQTRYNINQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPVSVLIKLPAEQPTVTGGGSESEENVSLAEQITDVVKQPAFIAGIGGACWVILMGFSVWIYCRRKKRKELSHYTAS------FAYTPAVGFPHGE-SSGLN-GRPGMLGANMGN-YPWLADSWPTTNLVHNGKDSVN-CCTSKHETPERY------------------------YNEAGISNYLNQNEKYSAD--SNEGPIYSTIDPTSEDLR--SFTAQ----------------YSQHTTPYASTPIMPFTNQAPCSPE-----QDGSHWMT--------QPGTSNAQYAQPDRSKTEN-------------------------------------VKQPKQKLMG---KPVKTPSLNWMDALPPPPISGDLEQCDEEDDNELIQDMGSDEEEWCPPLPERSYLMD----GMVEDG--------PVPPPRGEASSP-TTSYSHQSTATLTPSPRDD-GHFHD--IPRLHQLEQPHMTRRLPCGPVPVPRAPSPPLTQ---SNPNLSANQ-----ECPDNTVP--------------------------------HRSAHKRDLSQGAAQSVEN---------------------------------------------------------------------------ISNTTPGRARPSADHTSS----GQKSKVKKKAS----------KSAQYRRDILQGDLPPPPEPPPEDQDNCAHVGG-------------------------------------FECGQTSLERAGSSNSSMERREQSTPN--------RKNSAHRRIDADDDLIPYNKPNFLSRGQMSS--NCSTTGSSSSRGSTGSRGQ--------------------GTGRKRNDEMR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W213-1", "uniprot_id": "Q9W213_DROME", "id": "Q9W213-1", "name": "", "aln": "--MHPMHPENHAIARSTSTTNNPSRSRSSRMWLLPAWLLLVLVASN---------------------------GLPAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTN--EKKSHRVQFKDGALFFYRTMQGKKEQ-DGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHA----PPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPN---SSHGRQHVAADGTLQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLD-ERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGN-RYSIIQGSSLRVDDLQLSDSGTYTCTASGERGETSWAATLTVEKP-GSTSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISVPSGLSNTIKTIEADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADEKYVEGLRIHYKDASVPSAQ---YHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPSNSKTALTYEDVPSAPPDNIQIGMYN---QTAGWVRWTPPPSQHHNGNLYGYKIEVSAGNT-MKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMDPTHHVHPPRAHPSGTHDGRHEGQDLTYHNNGNIPPGDINPTTHKKTTDYLSGPWLMVLVCIVLLVLVIS-----------AAISMVYFKRKHQMTKELGHLSVVSDNEITALNINSKESLWIDHHRGWRTADTDKDSGLSESK-----------------------------LLSHVNSSQSNYNN--SDGGTDYAEVDTRNLTTFYNCRKSPD-----------NPTPYATTMIIGTSSS--------------------------------------------------------------------------------------------ETCTKTTSISADKDSGTHSPYSDAFAGQVPAVPVVKSNYLQYPVEP----INWSEFLPPPPEHPPPSS---------------------TYGYAQGSPESSRKSSKSAGSGISTNQSILNASIHSSSSGGFSAWGVSPQYAVACPPENVYSNPLSAVAGGTQNRYQITPTN------------------------------------------------QHPPQLPAYFATTGPGG------------------------------------------------------------------------AVPPNHLPFATQRHAASEYQAGLNAARCAQSRACN------------SCDALATPSPMQPPPPVPVPEGWYQPVHPNSHP-----------------------------------MHPTSSNHQIYQCSSECSDHSRSSQSHKRQLQLEEHGSSAKQRGGHHRRRAPVVQPCMESENE-------NMLAEYEQRQYTSDCCNSSREGDTCSCSEGSCLYAEAGEPAPRQMTAKNT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ***:*:*.*::*.:.**:** *:.**:* * :**:*.* * * : ::**: : *:*** * ::*:: : * * * ***:* :* *.*::***::*:****** * :. ** **.*::** **:* *** : * :. :.: . : **:*::: . * * * *:. *: * ::* *.: * :* *::.* . : .. * *.. *** * . *:*::.::* .* * * :* : . . * *:* * :.* :*: .* .:* *: ** :. :* :: . . * : * :.*.* *::** :** . *:*. .* *: * * :* :. * *** *.:..:..* .:. *:: . : **:: ** ***: . * * . * * * : * :: . : : . . * : : * * *:* *. **::* . : : . *..* * * ::: .:::* * . .* :* ** . * . *: * .: ** *.: *:*:*** .. *:* ** :*:.::* : : : * :.: :. : . ::.: * :. : ::* :: :: : . .* *: * :: : * * *: **..* : : : * * ** . :** : *:: ..:: : * : . *. : * .* * : : * ** * * * . : . :: . .. . : : * :. . :. . * . . . : . *. :* . :. * . . : : : . * * . ** : . :*:.: .: . . . . . : . . * . : : * :* : : . . ..: . . ", "identical_positions": 220, "similar_positions": 297, "identity": "12.3%" }, { "cls_id": "homologset.agr.FB:FBgn0005632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q93008-1", "uniprot_id": "USP9X_HUMAN", "id": "Q93008-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9X", "aln": "----------------------------MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPP-DEQGQGDAPPQLEDEE-----------PAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSS----VQLPEDELFARSP-DPRSPKGWLVDLLNKFGTLNGFQILHDRFING----------------------------SALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHRHG------NPEEEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSQTQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMRLYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQSNDDIASRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLD-----------------GDKDSVN-CARQEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFVVRFPNQGRQVDDLEVWSHTNDTIGSVRRCILNRIK-ANVAHTKIELFVG-GELIDPADDRKLIGQLNLKDKSLITAKLTQISSNMPSSPDSSSDSSTGSPGNHG-NHYSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAIC--------------------------LDHAKLGESSLSPSLDSLFFGPSASQVLYLTEVVYALLMPAGAPLADDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPGVEGVNPMTQINQVTHDQAVVLQSALQSIPNPSSECMLRNVS--VRLAQQISD----EASRYMPDICVIRAIQKIIWASGCGSLQLVFSPNEEITKIYEKTNAG-NEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIIDLLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGIEETILEGHLGVTKELLAFQTSEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIP-VCGSPPTINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQ--LIQQSEQSESETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNG--GDGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAITTRPHQIIMPSAIERSVRKQNVQFMHNRMQYSMEYFQFMKKLLTCNGVYLNPPPGQDHLLPEAEEITMISIQLAARFLFTTGFHTKKVVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPS----PFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPPLPNPFGDPNLS-QPIMPIQQNVADILFVRTSYVKKIIEDCSNSEETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDDQD---------APDEHESPPPE------------------------------------DAPLYPHSPGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGSEEVSPP-QTKDQ----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70398-1", "uniprot_id": "USP9X_MOUSE", "id": "P70398-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9X", "aln": "----------------------------MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPP-DEQGQGDAPPQIEDEE-----------PAFPHTDLAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLSKKGLDVKSEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNTHRLVELCVAKLAQDWFPLLELLAMALNPHCKFHIYNGTRPCESVSSS----VQLPEDELFARSP-DPRSPKGWLVDLLNKFGTLNGFQILHDRFING----------------------------SALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHRHG------SSEDEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSQSQRSPHVFYRHDLINQLQHNHALVTLVAENLATYMESMRMYGRDNEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQSNDDIACRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLD-----------------GDKDSIN-CARQEAVRMVRVLTVLREYINECDSDYHEERTILPMSRAFRGKHLSFIVRFPNQGRQVDDLEVWSHTNDTIGSVRRCILNRIK-ANVAHTKIELFVG-GELIDPGDDRKLIGQLNLKDKSLITAKLTQISSNMPSSPDSSSDSSTGSPGNHG-NHYSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTTIEKLRAIC--------------------------LDHAKLGESSLSPSLDSLFFGPSASQVLYLTEVVYALLMPAGAPLTDDSSDFQFHFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPGVEGVNPMTSVNQVTHDQAVVLQSALQSIPNPSSECMLRNVS--VRLAQQISD----EASRYMPDICVIRAIQKIIWTSGCGGLQLVFSPNEEVTKIYEKTNAG-NEPDLEDEQVCCEALEVMTLCFALIPTALDALSKEKAWQTFIIDLLLHCHSKTVRQVAQEQFFLMCTRCCMGHRPLLFFITLLFTVLGSTARERAKHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGVEETILEGHLGVTKELLAFQTPEKKFHIGCEKGGANLIKELIDDFIFPASNVYLQYMRNGELPAEQAIP-VCGSPATINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDDVFGYPQQFEDKPPLSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQ--LIQQNEQSESEKAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNG--GDGEKNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIGHDDEVIRYISEIAITTRPHQIVMPSAIERSVRKQNVQFMHNRMQYSLEYFQFMKKLLTCNGVYLNPPPGQDHLSPEAEEITMISIQLAARFLFTTGFHTKKIVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGPCPS----PFASPGPSSQAYDNLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSRMQSSINGNPSLPNPFGDPNLS-QPIMPIQQNVVDILFVRTSYVKKIIEDCSNSDETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDDQD---------APDEHESPPPE------------------------------------DAPLYPHSPGSQYQQNNHVHGQPYTGPAAHHMNNPQRTGQRAQENYEGGEEVSPP-QTKGSVKCTY-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00507-1", "uniprot_id": "USP9Y_HUMAN", "id": "O00507-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9Y", "aln": "----------------------------MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQHEDEE-----------PAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRFFRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCELISSN----AQLPEDELFARSS-DPRSPKGWLVDLINKFGTLNGFQILHDRFFNG----------------------------SALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEINKVISSVSYYTHRHS------NPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYSCSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYRHDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVIQSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFD-----------------GDKNSIN-CARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQVDELDIWSHTNDTIGSVRRCIVNRIK-ANVAHKKIELFVG-GELIDSEDDRKLIGQLNLKDKSLITAKLTQINFNMPSSPDSSSDSSTASPGNHR-NHYNDGPNLEVESCLPGVIMSVHPRYISFLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVC--------------------------LDHAKLGEGKLSPPLDSLFFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNTDMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQSALQSIPNPSSECVLRNES--ILLAQEISN----EASRYMPDICVIRAIQKIIWASACGALGLVFSPNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIIDLLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTLLRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELLAFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIP-VCSSPVTINAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQD-----SESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENE--LIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNG--KDDQTDHWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIAR-PHQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPS----PFASPGPSSQACDNLSLSDHLLRATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLS-QPIMPIQQNVLDILFVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLERSHSARMTLAKACELCPEEEPDDQD---------APDEHEPSPSE------------------------------------DAPLYPHSPASQYQQNNHVHGQPYTGPAAHHLNNPQKTGQRTQENYEGNEEVSSP-QMKDQ----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AW48-1", "uniprot_id": "A0A8M3AW48_DANRE", "id": "A0A8M3AW48-1", "name": "ubiquitinyl hydrolase 1", "aln": "----------------------------MTATTRGSPVGGNDGQGQAPDGQSQPPLPQNQTSSPNSSNENSPVSPP-DDQGQGDSPTPLEEEE-----------PAFPHTELAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLCKKGIDVKCEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNAHRLVELCVTKLSQDWFPLLELLAMATNPHCKFHIYNGTRPSETVPAG----VQLAEDELFARPP-DPRSPKGWLVDLINKFGTLNGFQTLHDRFMSG----------------------------QALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHRHG------NPEEEEWLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKESWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDQALSAHIKILDYSCSQDRDTQKMQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSQTQRSPHVFYRHDLINQLQHNHALVTLVAENLSAYMENMRQFSKEHADFDPQTVRPGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVFLCDREACFKWYSKLMGDEPDLDPDINKDFFENNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQGSDDIASRAIDLLKEIYTNLGPKLQANQVEIHEDFIQSCFDRLKASYDTLCVLD-----------------GDKDSIN-CARQEAIRMVRVLTVLREYITECDSDYHEERTILPMSRAFRGKHITLVVRFPNQGRQVDDLDIWSHTNDTIGSVRRCILNRIK-ANSTHTKIELFIG-GEIIDPADDRKLIGQLNLKDKTLITAKLTQVSANMPSSPDSSSDSSTGSPGNHG-NHYSDGPNPEVESCLPGVIMSLHVRYISFLWQVADLGCNLNMPLLRDGARVLMKLMPPDNATVENLRAIC--------------------------LDHAKLGENSLSPTLDSRFFGPSPSQVLYLIEVVYALLMPASGTLGEDASDFQYNFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAVG--FGHVKSVAEACQPVVEGTIPVSPINQTTHDQALVLQNALQNIPNPSAECMLRNVA--IRLAQQISDENFFQASKYIPDICVIRAVQKIVWASGCGSVQHVFSSNEEISKIYEKTNAG-NEPDAEDEQVCCEALEVMTLCFALMPTALDALSKEKAWQTFIIDLLLHCQSKSVRQMAQEQFFLMATRCCMGHRPLLFFITLLFTVLGSTAKERAKHAADYFTLLRHLLNYAFNSNINLPNAEVLLNNEIDWLKRIRDEVKRTGEPGVEETILEGHIGVTKELLAFQTPEKKFYIGCEKGGASLIKELMDDFLFPASNVYLQYMKSGEFPTEQAIP-VCSTPATINAGFELLVALAIGCVRNLKQIVDTLTDMYYLG-----CEPLTEWEYLPPVGPRPTKGFVGLKNAGATCYMNSVIQQLYMIPPIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDEVFGYQHQFDDKPSLSKSEDRKEYNIGVLRQLQVIFGHLASSRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSMEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGSDVHPENQQQVIQQNEPSEPEPPCSSRYRLVGVLVHSGQASGGHYYSYIIQRNGSGGEGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTLDKDSELVKYITELTVSSKPHQVKMPSAIERSVRKQNVQFMHNRMQYSLEYFQFIRKLLTCNSVYLNSPPGQDHLLPEAEEMAMISIQLAARFLFSTGFHTKKIVRGPASDWYDALCILLRHSKNVRYWFAHNVLFAYPNRFSEYLLECPSAEVRGAFSKLIVFIAHFSLQDGPCPT----PIASPGPSSQGCDNLSLSEHLFRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGLAEKTQLLKLGVPATFMLVALDEGPGPPIKYQYAELGKLYTVVSQLVRCCDVTSRMQSSINGNPPLANPYGDPNTT-TPIMPLQQLVVDILFVRTSYVKKIIEDCSNSEDTIKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILFIEDSWQTHRIHNVLKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNCSVAYQILQSNGDLKRKWTWAVEWLGDELERRPYTGNTQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDEQE---------ALDEQDPSPPE------------------------------------DTALYPHSPGSKFQQNNLPHTQPYTGPAAQHVNNPQRPGPRAQENWEPPEETPQPSQTKD-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A1B0GWT2-1", "uniprot_id": "A0A1B0GWT2_RAT", "id": "A0A1B0GWT2-1", "name": "ubiquitinyl hydrolase 1", "aln": "----------------------------MTVTTRGSPVGENESQGQAPDGQSQPSFQQNQNS---------PATPP-DEQGQGDAPPQHEEED-----------PTFPHADLAKLEDMINRPRWVVPVLPKGELEVLLEASIDLTKKGIDAKSEACQRFFRDVLTVSFTKILTDEAVSGWKFEIHRCIINNTHRLMELCVAKLSQDWFPFLELLAIALNPHCKFHVYNGARPCESVSSS----VQFPEDELFACSP-DLRSPKGWLVDLINTFGTLNGFQILHDRFISG----------------------------SALNVQTIAALIKPFGQCCEYLTQHTLKKYFIPVIEVVPQLLQKLTNEELKKEAKTEVKNDAISMIIKFLKNLASRIPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEINKVLSSVSYYTHRHG------NSE-EEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRFVIKEKALTLQDLNNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAQKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDCFIEEFRTNNKWVIPALKQIKEICSLFGEAPQNLSQTHRSPHVFYRHDLISQLQHNHALVTLVAENLATYMNSIRLYARDHEDYDPQTIRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCASQAKQIWHCLAENAVYFSDREACFMWYSKLMGDEPDLDPDINKEFFESNVLQLDPSLLTENGIKCFERFFKTVNCREGKLMIKRKVYMMDDLDLIGLDYLWKVVIQSNDDISNRAIDLLKEIYTSLGPRLQANQVVIHEDFIQSCFDRMKSSYDTLHVLD-----------------SDKDNIFSCARQEAIRIVRILTVLREYISECDSDYHEERMILPMSRAFRGKHLSLTVRFPNQSKEVDDLDILSHTNATIGSVRRCILNRIN-ANVTHTKIELFIG-GELIDSEDDRKLVEQLNLKDKSLITAKFLQINSNMPSSPDSSSDSSAGSPGNHCHNNYRDVPNSEMENCLPGVIMSLQPRYVSFLWQVADLGSMLTMPTLRDGARILMKLMPPDNTTIENLRAVC--------------------------SDHLNLGERRLGQSLHSLFFGSSASKVLYLTEVVYILLMPAGAHLADISSDFQYHFLKNGGLPLVLSMLIQNNFLPNTDVETRRDAYFSALKIAKLLLTTIG--YGHVQAIAEACQPVADGTDPKTPINQATHDQAVVLQNALQSIPNPSSECMLRNVS--IRLAHQISG----LASRYIPDICVIRAIQKIIWTSGCGSLELVFSPHEDITKTYKMTTSTRSNPEVKDEQVCCEALEVMTLCFALIPTALDSLSKEKAWQSFVIDLLLYCPSKTIRQLAQEQFFLICTRCCMGHRPLLFFITLLFTILGSAATEKGKHSDVYFPLLRRLLTYAYNSNIHIPNVDVLLNDEINWLKRVRDYIKNTGETSVEDPILEGHLGVTKELLSFQTPDKKYHIGCKAGGANLVKELIDDFIFPASKAYLQYSRSGEMPNKQTIP-VCGSPATVNAGFELLVALAFGCVRNLKQIVNCLTEMFYIGTPVN---TLAEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIENIWNDTDDDTFKDERQD-----SENNIDPRDDVFGYPHQFEDKPTLNKAEDRKDYNIGVLKHLQITFGHLAASQLQYYVPRGFWQQFRLWGEPVNLREQHDALEFFNSLVDSLDEAFKALGHPTLLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPSVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGATKLEGDGVHPQTQ--LIKQNEQSENVVPGSTKYRLVGVLVHSGQANGGHYYSYIIQRNG--KDNNRGRWFKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDITDEDNEMITYLSELTITR-PHQIMSP-AIERSVWKQNVQFLHNQMQFSLEYFQFIKKLLTCNAVYLNPAPGQDHLPPEAEDITMISIQLAARFLFTTGFHTKKIVRGPANDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGTFAKLIVFIAHFSLQDGSSSS-FASPFATPGPYSQIYDNLSLSDHLLKAVLSLLRREVSEHGRHLQQYFNLFIMYASLGLAEKTQLLKLNVPTTFMLVSLDEGPGPPIKYQYAELGKLHSVVSQLIRCCSVSSRMQSSINGNPPLPNPFGDPNLS-QPIMPIQQNVADILFMRTTYVKKIIEDCSNSEETVKLLRFCCWENPQFSCSVLSELLWQVAYSYAYELQPYLDLLLQIILLEDSWQAHRIHNALKGIPSDRDGLFDTIQHFKNHHQKRAYQCIKWMVTLFNSCPVAYQILQGNGDLKKKWTWAVEWLGDELERKPYSGNPHYTYSNWSPPIQSNETANGYFLERSHSARMTLAKACDLCPEEDTDDQD---------APDEHESPAPQ------------------------------------ERTFYLYSHRSQYQQS-YVPEQPYSGLTEHHLNEPQK-NDEPQETHESSEEESSS-LIKDQ----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPU6-1", "uniprot_id": "USP9Y_MOUSE", "id": "F8VPU6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9Y", "aln": "----------------------------MTITTRGSPVGENESQGQTSDGQPQPSFQQNQISSSDSSNETSPTTPP-YEQGQGDAPPQHEEED-----------PSFPHTDLAKLEDMINRSRWVVPVLPKGELEVLLEASIDLTKKGLDVKSEACQRFFRDVLTVSFSKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPFLELLAIALNPHCKFHVYNGARPCESVSSS----VQFPEDELFACSP-DLHSPKGWLVDLINTFGTLNGFQILHDRFTSG----------------------------SALNVQTIAALIKPFGQCYEFLTQHTLRKYFIPVIEVVPQILQKLTNEELKKETKTEVKNDTISMIIKFLKNLASRIPGQEETVKNLETFRLKMILRLLQISSFNGKMNALNEINKVLSSVSYYTHGHG------NSE-EEWLTVERMTEWIQQNNILSIVLQDSLHQPQYVEKIEKILRFVIKEKALTLQDLNNIWAAQAGKHEAIVKNVHDLLAKLAWNFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDCFIEEFRTNNKWVIPALKQIKEICSLFGEAPQNLSQTHQSPRVFYRHDLISQLQHNHALVTLVAENLAAYMNSIRLYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCVSQAKQIWNCLAENAVYFSDREACFMWYSKLMGDEPDLHPDINKEFFESNVLQLDPSLLTENGMKCFERFFKTVNCREGKLMIKRKIYMMDDLDLIGLDYLWKVVIQSNDDISSRAIDLLKEIYTSLGPKLQANQVVIHEDFIQSCFDRLKASYDTLCVLD-----------------SEKDNIFSCARQEAIRMVRILTVLREYISEYDSDYHEERMILPMSRAFRGKHLSFTVRFPNQGKEVEDLDILSHTNATIGSVRRCILNRMN-VNVAHTKIELFIG-GELVASEDDRKLVEQLNLKDKSLITAKFIQINSNMPSSPDSSSDSSAGPPGNHSHNNYRDVSNPEMEKCLPGVIMSLQPRYISFLWQVADLGSMLTVPTLRDGARILMKLMPPDSTTLEQLRALC--------------------------SDHVNLGERRLGQSLHSLFFGSSASQVLYLTEVVYTLLMPAGAPLADISSDFQYHFLKSGGLPLVLSMLIQNNFLPNTDVETRRDAYFSALKIAKLLLTIVG--YGHVQAIAEACQPVADGTDPKTPINQVTHDQAVVLQNALQSIPNPSSECMLRNVS--VHLAQQISG----LASRYIPDICVIRAIQKIIWAAGCGSLELVFSPNEDITETYKMTTSTRSNLEVKDEQVCCEALEVMTLCFALIPTAMDSLNKEKAWQSFVIDLLLYCPSKTVRQLAQEQFFLICTRCCMGHRPLLFFITLLFTILGGAANEKGKHSDVYFTLLRRLLTYAYNSNIQVPNVDVLLNDEIDWLKRVRDYIKNTGETNVEDPILEGHLGVTKELLSFQSPEKKYHIGCKTGGANLVKELIDYFIFPASKAYLQYMRSGELPIKQAIP-VCGSPATINAGFELLVALAFGCVRNLKQIVNCLTELFYIGTPVTTCEAVGEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIDSIWSDTDDDIFKGEKQD-----SENNVDPRDDVFRYPHQFEDKPTLSKVEDRKEYNIAVLKHLQITFGHLAASQLQYYVPKGFWQQFRLWGEPVNLREQHDALEFFNSLVDSLDEAFKALGYPTVLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPSVLTIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGATKLEGDSVNPQTQ--LIKQNEQSESVIPGSTKYRLVGVLVHSGQANGGHYYSYIIQRNG--KDSKRSHWFKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDITDEDDEIITYISELTFTR-PHQIMSP-AIERSVWKQNVQFLHNQMQFSLEYFQFIKKLLTCNAVYLSPAPGQDHLLPEAEDITMISIQLASRFLFTTGFHTKKIIRGPANDWYDALCILLRHSKNVRFWFVHNVLFNVSNRFSEYLLECPSAEIRGTFAKLIVFIAHFSLQDGSSPSPFTSPFANPGPYSQIYDNLSLSDHLLKAVLSLLRREVSEHGRHLQQYFNLFIMYASLGLAEKTQLLKLNVPATFMLVSLDEGPGPPVKYQYAELSKLHSVVSQLIRCCSVSSRMQSSINGNPPLPNPFGDPNLS-QPIMPIQQNVADILFMRTTYMKKVIEDCSNSEDTVKLLLFCCWENPQFSCSVLSELLWQVAHSHAYELQPYLDLLLQIILFEDSWQAHRIHNALKGIPNDQDGLFDTIQHSKNHHQKRAYQCIKWMVTLFNSCPVAYQILQGNGDLKNKWTWAMEWLGDELERKPYSGNPQYTYSNWSPPVQSNETANGYFLEKSHSAKMKLTKACDLYPEEDPDDQD---------ALDEHVSHAPQ------------------------------------DRTFYLYSHRSHYQQN-YVPEQPFSGPASHHLNNPQK-NDKPQETHESNEEISSC-LIKDQ----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55824-1", "uniprot_id": "FAF_DROME", "id": "P55824-1", "name": "Ubiquitinyl hydrolase FAF", "aln": "MTFDTRRHTTGQPGSTAPSSSSSTTSTTTTTTSPAQSAGSGSGIGTGTGTVANSSLPGGGSGSLDGNQDQQPATDSQSSDDVAASLSANSVDSTITIVPPEKLISSFPTTKLRSLTQKISNPRWVVPVLPEQELEVLLNAAIELTQAGVDHDCEPCVEFYRNGLSTSFAKILTDEAVNSWKNNIHHCILVSCGKLLHLIAIHMQRDNPYLLDLLAIVFDPENKFNTFNAGRQPECFAAPDYIWGQLDSNKMYARPPPEPKNARGWLVDLINRFGQLGGFDNLLERFNIGLELLKRNQNKCTGKNISVEGRVENGAQDNRLTLALIHSLLRPFGQCYELLMPATIAKYFMPTWNVVLDLLDSFTDEELKREVKPEGRNDYINGIVKSARLLASRLTGQEELIRDLEMFRLKMILRLLQVSSFNGKMNALNEINKVLSSVAYFSHRSQPLPHCMPEDEMDWLTADRMAQWIKSSDVLGVVLKDSLHQPQYVEKLEKIIRFLIKEQALTLDDLDAVWRAQAGKHEAIVKNVHDLLAKLAWDFTPEQLDHLFEAFQASMTTANKRQRERLLELIRRLAEDDKNGVMAQKVLKLFWTLAHSQEVPPEVLDQALGAHVKILDYSCSQERDAQKTIWLDKCVDELKSGDGWVLPALRLIRDICCLYDTTTNHAQRTQTST---NRQQVIERLQNDYSLVILVTNSLTAYMEKVRQMVTDSPGLDATRILIDGRFPHHVQIAERLEFLKFLLKDGQLWLCADQAKQIWHCLAVNAVFPADREECFRWFGKLMGEEPDLDPGINKDFFENNILQLDPHLLTESGIKCFERFFKAVNSKEDKLKAIHRGYMLDNEDLIGKDYLWRVITTGGEEIASKAIDLLKEVSTALGPRLQENIAEFHEMFIGECCSRLRTHYGNIVILGKTQLQEELDAPDQSDNTNDESKDSKMRFIEAEKMCRILKVLQEYVKECDRSFSGDRVHLPLSRVTRGKNTILYIRFQNPGRSIDDMEIVTHSNETMAAFKRNLLKRIKGTSTANIKVDLFYANDEMIGVSDEINPLYQYTIRDKMNLTAKLTPVGTGLASSPDSSSDSSTGSPPRPC----PDMQRVESESTLPGVIISQNYQYTEFFLKLYQLGSDLEHGRLRDSAKVLLHLLPCDRQTIRQLKIMCKVPKAAVTVAVTGDKIAKDEEEKLYPTEQAGIEDEEEHCTPEQMFLHPTPAQVLYNLSVLHGLLIPALDPLGESALLVQSAWMHSGCAHFVLELLTKNNFLPSADMHTKRASFQCVLRLAKLFLYIVGSVLSRVGDEPMICDLDNGSRSQVDILKQNFSTMPSSSQGTLRAISAKLAVILAREMLSASPEGDRCRTLFSSTLQWSCPDISTIKAVVQLAWASSCGNLQALGNSSGDFEDEVIVPDGQ-------DFSMCKEALEVLTISFILNPSANEALTSDPNWPKFITSIVLKNPLRHVRQVASEQLFLASTYCAGDRRPFVYMVNLLVGALKTLVPQYESTCAEFFSVLCRTLSYGCIYNWPLQISEGLLGDEIKWLQRIRENVHATGDTQVHEELLEGHLCLAKELMFFLGADSKAQLN------ELIHELIDDFLFTASREFLHLRRHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVPNMKLLTNTLIDFVCTDT-----DPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDG-LHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDN---CQTNVET-------TKYELTGIVVHSGQASGGHYFSYILSKNP---ANGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKRWWNAYMLFYTRCDQTPVQYEPSVEQLSLAESR-NMVLPLPKPIERSVRHQNIRFLHSRSIFSVEFFNFIKKLVSCNLLSARS----NKITPAAEELSLLGVQLASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSRLGEYILMAPSPDVRTVFVKLVVFFCHFAINDEPLTG---------------YDGANLCEQVLISVLRLLKSEAADYGKHLPHYFSLFSMYVGLGTREKQQLLRLNVPLQFIQVALDDGPGPAIKYQYPEFSKLHQVVSHLIRCSDVSEKCQSSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLFNRTGYIKKVIEDTNVGDEGLKLLQYCSWENPHFSRAVLTELLWQCGFAYCHDMRHHTDLLLNILLIDDSWQHHRIHNALNGVAEEREGLLETIQRAKTHYQKRAYQIIKCLTQLFHKSPIALQMLHTNSNITRHWSIAVEWLQGELDRQRGIG-CQYNSYSWSPPAQSNDNTNGYMLERSQSAKNTWSMAFELCPDEVSEKTDENNEPNLETNMDENKSEPVAQPGGVLEGSTGGTEQLPENKTPTTSSPSTAAWPARGDSNAIPRLSRQLFGAYTSTGSGSTSGGSAPTSALTTTAGSGANSETESSAQETTGETTINGLTNSLDQMEITAKKKCRRVIIKKLVESKDEEDATTATTAATTEVTTSPATAIATAATLEPAGMSELTTMVEKNLIISQENPQAKSSLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ....* ... * . .: : . . .: . .:. . : . . :. .:** :.* .* : *...********: ******:*:*:* *:* ..*.* .*:*: *: **:*** ****..** :**:**: . :*:.* . :: :* :*:***:. :*. **: :*. * * ..: *: .::::* .. : :..:******:* ** *.**: * :** * . *.: * :*::***** * * *: ***:* ::* .:*:.:*:****:*.* * :** :. *:* : ****:.**:* :::** ***********:************:***:***:*::* : :***.:**::**:..::*.:**:***********:***:**:***:****:**: :* **********************:*:* ******:.*: * *.*.*:***:*************:****:***:*:*.**:*::** :::* **.**:*********:**:** *:* ::*:::.: **:***: *::**.*:. :.:: .::: *. *:::*.:**::::** **::.*::**:.:* : . *. : ..*:.* :: ***:**:***********. ******:*** ***: .*** ** *:.****:****.*.***:***.*:***** ****.*:********:**.:* ** :: **:*: :*** ****:*: ..::*: :*******: * ***:*: * . :** ** .* .*::: *..: ::. .::.. ** :: *:*.*::**:.* * .: :* **:**. ***: : :** * .:.:::::: :*:* *:.:.:* :::*:: .. :: *::** . .*:: *: : : * .::** :***: :. .:.**********:..* . * . * *. *****:* : :* .*: :: :**. * ***.*::*::*:* * ::.:*: :* :: : : . .. *: .:.::*** .*:: **:** * : : .* :::.* :**.:* :*****.:*:.*:* :: .*::***:* :* .:* . *: . ::* . *.:*: *. : : *: ... . ***..*:*: :: *::.** : : .. :. . . * .:* *****:*:.* * *:* ::*..: * .*: .::* : :**:*.**:** .* *. .:**:::::.**. * . : . . :*.:* : *.*. * : : ** .**.**:*:*: :: **:. :.: :****: ::***: * .:.* :. .*::**:* *:*.**. :*: : *.: . . * ** :* *: *. :**:**. ** *:* :.: * :: . .: **:******.**.*** **************:*****:*.:* .** .. . :* .. . .* . :. . . : **:*:: :*:::* *.**. * ******:*:* :*:* *********:**:*** **::****.:**** * ::. .*****:****** *****. **.*:.:.******..* :*:***:**:*****:****:**:*** ****: :**** **:******:**:** ************* *** ****:* ::** . *. : : . : ::*.*.*::******.****:***:.:* . :*:*****:******.:***** :*********.:*: :***.***********:*** : * : * .:: : : . .***** :**::*:*.: :*:*:*:*::**::** : . : : * **:::::.:***::*** ***:*** :**.. :*****. :* * ** **.::.*: ..*:.**:* .**.::* .* **:**:.**:::* . . *. .*.:::: :.* **: *.:::*:** :**.** **..** ** ***:*.** *: *:**:****.:****.*:.**: ***:*:**..*:. *** :. .*.**: * * : : *:. *:** ** *:**:*** . .:: :*** :*.****:** :**:***** ..:: :::: : ***::*::::**** *****.*:*:..:::**::***: *.*:****** ** :. ** ...:* *:*: *.::..:*: *:*** .**:*: * :*. .**** ***:.:***:**:*:**: . : * :* *:* .:. : **: . . : . : . :* : . . .:. * : . . ", "identical_positions": 1042, "similar_positions": 837, "identity": "36.72%" }, { "cls_id": "homologset.agr.FB:FBgn0005636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6K1-1", "uniprot_id": "A0ABK0M6K1_RAT", "id": "A0ABK0M6K1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MVGVPG---------AAAFQLG------CEKRVPAMPGSPVEVKIQSRASPPIMPPLPP-INPGGPRPVSFTPTA--------------------------LSNGISHSPPTLNGAPSPPQRFSNG-PASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPESFFYRRDENNFERDTVPPEPTAKRVCTISPAPRHSPALTVPLLSA---------GGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRERHHNLSLNGGYQD-ELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRCNENTELRKTGTELV-----------SRQHSPGSTDSLSNDSQREFTSRPAAGYVPVEFWKKT------------------EEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQSLHGHS-----------PHSQSRSLLPGGRGS---ARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70374-1", "uniprot_id": "MTG8R_MOUSE", "id": "O70374-1", "name": "Protein CBFA2T2", "aln": "--------------------------------------------------------------------------------------------MVGVPG---------AAAFQLG------CEKRVPAMPGSPVEVKIQSRSSPPIMPPLPP-INPGGPRPVSFTPTA--------------------------LSNGINHSPPTLNGAPSPPQRFSNG-PASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPE----RRDENNFERDTVPPEPPAKRVCTISPAPRHSPALTVPLMNP---------GGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRERHHNLSLNGGYQD-ELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRFNENTELRKTGTELV-----------SRQHSPGSTDSLSNDSQREFTSRPATGYVPVEFWKKT------------------EEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQSLHGHS-----------PHSQSRPLLPGGRGS---ARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43439-1", "uniprot_id": "MTG8R_HUMAN", "id": "O43439-1", "name": "Protein CBFA2T2", "aln": "--------------------------------------------------------------------------------------------MAKESGISLKEIQVLARQWKVG------PEKRVPAMPGSPVEVKIQSRSSPPTMPPLPP-INPGGPRPVSFTPTA--------------------------LSNGINHSPPTLNGAPSPPQRFSNG-PASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPE----RREENSFDRDTIAPEPPAKRVCTISPAPRHSPALTVPLMNP---------GGQFHPTPPPLQHYTLEDIATSHLYREPNKMLEHREVRDRHHSLGLNGGYQD-ELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRYNENTELRKTGTELV-----------SRQHSPGSADSLSNDSQREFNSRPGTGYVPVEFWKKT------------------EEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQS-----------PHGQGRPLLPVGRGSS--ARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K0G0-1", "uniprot_id": "A0A0G2K0G0_RAT", "id": "A0A0G2K0G0-1", "name": "", "aln": "--------MNTKRRCGGRAAGRLARSPPEGNLRGRAGGGGAGRGVGAAPQRSRADKSQGSEDVTCYRELLLAARGNLHLKITEGEGEDLPFVVLGEEEAAALASLLSPNTSAIQTGTRGDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPP--TTQGAPRTSSFTPTT--------------------------LTNGTSHSPTALNGAPSPPNGFSNG-PSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDIS-PEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSPVDSSELLLDVNENGKRRTPD----RTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQP----------NGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQE-EMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSGSS---------SHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKA------------------EEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAED--------ALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQ-------------QGETPAVSSSVTP--------SSGAGSPMDTPPAATPRSTTPGTPSTIET-TPR-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61909-1", "uniprot_id": "MTG8_MOUSE", "id": "Q61909-1", "name": "Protein CBFA2T1", "aln": "---------------------------------------------------------------------------------------------------------------------MPDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPP--TTQGAPRTSSFTPTT--------------------------LTNGTSHSPTALNGAPSPPNGFSNG-PSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDIS-PEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSPVDSSELLLDVNENGKRRTPD----RTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQP----------NGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQE-EMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSS---------SHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKA------------------EEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAED--------ALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQ-------------QGDTPAVSSSVTP--------SSGAGSPMDTPPAATPRSTTPGTPSTIET-TPR-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06455-1", "uniprot_id": "MTG8_HUMAN", "id": "Q06455-1", "name": "Protein CBFA2T1", "aln": "------------------------------------------------------------------------------------------MISVKRNTWRALSLVIGDCRKKGNFEYCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPP--TTQGAPRTSSFTPTT--------------------------LTNGTSHSPTALNGAPSPPNGFSNG-PSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDIS-PEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSPVDSSELLLDVNENGKRRTPD----RTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQP----------NGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQE-EMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSS---------SHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKA------------------EEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAED--------ALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQ-------------QGDTPAVSSSVTP--------NSGAGSPMDTPPAATPRSTTPGTPSTIET-TPR-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2T4-1", "uniprot_id": "A0A8M9Q2T4_DANRE", "id": "A0A8M9Q2T4-1", "name": "", "aln": "--------MHWDEMAGEIHVKRFNRS-------------GSRRTLSAALTPTR------------VPTVMLTSR------------------SIALDKQALHRLALPPYVSKRQ--STGNTGKKAGTMPDSPADVKTQPRSTPPTMPPPPPAVSQAVNRNASFTPTT--------------------------MLNGSSHSPTALNGAPSTPNGFSNG-PATSSTASLPTQQLPPACGARQLCKLKRFLTTLQQFGNDIS-PEIGERVRSLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARMAKQTPAQYLAQHEQLLLDAN--AISPLDSSEIMLELNEHGKRRTPD----RTKENAGDRDGLHQEHLAKRPCTVSPSQRFSPSSGLPAHPPPNGLPTHPPNGLPHPNPPAPQHYRLEDMALAHHYRDAYRHAEHRDVRDRHRQSAVHGARQE-EVIDHRLTDREWAEEWKHLDNLLNCIMDMVEKTRRSLTVLRRCQEADREEMNHWIRRYSDVEDMKKGGSSAQRPPPLPPHHNSSSSNTPNSSETQPLEIHRDFLHRPPSGYLPEEIWRKAGTTSIPLSPALKQLQNKQEEAVNEVKRQAMSELQKAVSDAERKAHEMISAERSKMERALAEAKRQASED--------ALTVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHVCGQGLPSSSGVPLGTPSTTSTSSSAPPTHSESTTPGPLSLAGQTSSGGSPKEASSSSVSRSTTPATPALMDS-SSR-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A303-1", "uniprot_id": "D4A303_RAT", "id": "D4A303-1", "name": "", "aln": "-----------------------------------------------MSQAS----------------------------------------TTLESGALLPG----PRGLHNG--SPAHRKEKAAAMPDSPAEVKTQPRSTPPSMPPPPPTSSQGATRPPSFTPHTHGEDGPATSLPHGRFHGCLKWSMVCLLMNGSSHSPTAIHGAPSTPNGFSNG-PATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDIS-PEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDAS--ATSPVDSSELLLEVNENGKRKTPD----RTKENGSDRDPLHPDHLSKRSCTLSPAQRCSPS-----------------NGLPHPTPPPPPHYRLEDMAMAHHFRDSYRHPDPRELRERHRPLAIPGSRQE-EVIDHRLTEREWAEEWKHLNSLLNCIMDMAEKTRRSLTVLRRCQEADREELNHWIRCYSDSEEGKKGPTPIS----------ARSLNSCSGSEGSQLDVHRDFTPRTLSGYMPEEIWRKA------------------EEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASED--------ALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPA----------AAVADPLPGQPDAT--------------ASPSEAGSAGPSRPCSPGPPVPLDTAVPR-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54972-1", "uniprot_id": "MTG16_MOUSE", "id": "O54972-1", "name": "Transcriptional corepressor CBFA2T3", "aln": "-----------------------------------------------MSQAST---------------------------------------TTLESGALLSG----PRGLQYG--SPAHRKEKAAAMPDSPAEVKTQPRSTPPSMPPPPPTSSQGATRPPSFTPHTHGEDGPATSLPHGRFHGCLKWSMVCLLMNGSSHSPTAIHGAPSTPNGFSNG-PATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDIS-PEIGERVRTLVLGLVNSTLTIEEFHAKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDAS--ATSPVDSSELLLEVNENGKRRTPD----RTKENGSDRDPLHPDHLSKRSCTLSPAQRCSPS-----------------NGLPHPTPPPPPHYRLEDMAMAHHFRDSYRHPDPRELRERHRPLAIPGSRQE-EVIDHRLTEREWAEEWKHLNSLLNCIMDMVEKTRRSLTVLRRCQEADREELNHWIRCYSDSEEGKKGPTPIS----------ARSLNSCSGPEGSQLDVHRDFTPRTLSGYMPEEIWRKA------------------EEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASED--------ALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPA----------AAVADPLPGQPDAT--------------ASPSEAGSAGPSRPCSPGPPGPLDAAVPR-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75081-1", "uniprot_id": "MTG16_HUMAN", "id": "O75081-1", "name": "Transcriptional corepressor CBFA2T3", "aln": "-------------MPASRLRDRAASS-------------ASGSTCGSMSQTH----------------------------------------PVLESGLLASAGCSAPRGPRKGGPAPVDRKAKASAMPDSPAEVKTQPRSTPPSMPPPPPAASQGATRPPSFTPHTHREDGPAT-LPHGRFHGCLKWSMVCLLMNGSSHSPTAINGAPCTPNGFSNG-PATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDIS-PEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDAS--ASSPIDSSELLLEVNENGKRRTPD----RTKENGSDRDPLHPEHLSKRPCTLNPAQRYSPS-----------------NGPPQPTPP--PHYRLEDIAMAHHFRDAYRHPDPRELRERHRPLVVPGSRQE-EVIDHKLTEREWAEEWKHLNNLLNCIMDMVEKTRRSLTVLRRCQEADREELNHWARRYSDAEDTKKGPAPAA----------ARPRSSSAGPEGPQLDVPREFLPRTLTGYVPEDIWRKA------------------EEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASED--------ALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHRDWEKHHHVCGQSLQGPT----------AVVADPVPGPPEAAHSLGPSL---PVGAASPSEAGSAGPSRPGSPSPPGPLDT-VPR-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KEZ2-1", "uniprot_id": "A0A0B4KEZ2_DROME", "id": "A0A0B4KEZ2-1", "name": "", "aln": "MMALDGKAIIKEEITDKDAYDAAAAAAAAVAAGAALAVASAAAVQVPPASSSSAGSASSAAAAATNNTTSAAATAAAISRRLKASSSGGDKSSTSSSSSKDSSHTSSSRSERDRERERERERERDRLCRTPPDSPPDSSRSLAPRSPHSPLQLHQHPQRNASVSPVV----------------------------NGSSSGGGGVGSSGTSPTPTPGSQHAASLAAAAAAAAAAHVEQARLVSKMRKFLGALVQFSQELGQPEVCERVRALVLSLCSGSISVEEFRLALQEAINLPLRPYVVPLLKNSIALVQREILALARATNQSALQYVTNNEQAVMEFAPHGVASAEFGDIFIQLEAPTSNGSSAVFK-RRSSDSMMEHGGHNGLQEWNEYMASGGAGYPPPPSKRLTLHP------AHSVVAYGEYGVSSAEGLPSAAAFMQRDERDLRMSEAQARHAAPPQRAGNPQPNPNAAAPGAPGAGGEEEWKNIHTMLNCISAMVDKTKRAITILQQRGIEPQHPNSGQEVTPAAMAELRRQTEEKV-----------------------------------------AEFKRNA------------------EDAVTQVKRQAVIEIQRAVVAAETRAAEIMTQERLRMEKFFMEMSRHSSGERDLDNKSPSMASAQNGSNLQQQCWNCGRKATETCSGCNMARYCSASCQYRDWDSHHQVCGNTRASELSAKHLHSASNLSLRNAMATRSPPTPNSAAHLQAAAAAAAAAAGAREAVSAPVGGPGAGIAVGTGAGSGGQSGGGGGGGGGGGGGAAAAAVAAATPGALVANGLGSKXRIRMMKPKKKYLC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* . ..* .* * * * *.:* . ** . . : .: .* ... ::* ::: . . . ** :.*:::** :* **..::. **: *:**:***.* ..::::***: **** *:****:*:*:** .:.*:***:* ** ::*.. **::::*: ::: :. : .::::::. .. :. * ..: .. . . . .* . * . * : . : *. . : : . :***::. **** *.:**:*::::*:: :. . : :: :: ::: *:**.:** **: *:*:** ** :* :::: ** :**: . : .*::: : :: :: .: :.********:******* ****.: **::**: **::**: . . . ... : . *.. : : ", "identical_positions": 120, "similar_positions": 176, "identity": "14.1%" }, { "cls_id": "homologset.agr.FB:FBgn0005638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05554-1", "uniprot_id": "CEBPA_RAT", "id": "P05554-1", "name": "CCAAT/enhancer-binding protein alpha", "aln": "---MESADFYEAEPRPPMSSHL-----------------QSPPHAPSNAAFGFPRGAGPAPPPAPPAAP-----------EPLGGICEHETSIDISAYIDPAAF------------------------------NDEFLADLFQHSRQQEKAKAAAGPAGGGG--DFDYPGAPAGPGGAVMSAGAHGPPPGYGCAAAGYLDGRLEP-LYERVGA-----------PALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPP--PHPHASPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPAMGAA------GLPGPGGSLKGLAGPHPDLRTGGGGGG-GAGAGKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESS-LVKAMG--NCA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53566-1", "uniprot_id": "CEBPA_MOUSE", "id": "P53566-1", "name": "CCAAT/enhancer-binding protein alpha", "aln": "---MESADFYEVEPRPPMSSHL-----------------QSPPHAPSNAAFGFPRGAGPAPPPAPPAAP-----------EPLGGICEHETSIDISAYIDPAAF------------------------------NDEFLADLFQHSRQQEKAKAAAGPAGGGG--DFDYPGAPAGPGGAVMSAGAHGPPPGYGCAAAGYLDGRLEP-LYERVGA-----------PALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPP--PHPHASPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHAAPALGAA------GLPGPGSALKGLAGAHPDLRTGGGGGGSGAGAGKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESS-LVKAMG--NCA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49715-1", "uniprot_id": "CEBPA_HUMAN", "id": "P49715-1", "name": "CCAAT/enhancer-binding protein alpha", "aln": "---MESADFYEAEPRPPMSSHL-----------------QSPPHAPSSAAFGFPRGAGPAQPPAPPAAP-----------EPLGGICEHETSIDISAYIDPAAF------------------------------NDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEP-LYERVGA-----------PALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAA------GLPGPGSALKGLGAAHPDLRASG-----GSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESS-LVKAMG--NCA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56261-1", "uniprot_id": "CEBPE_RAT", "id": "P56261-1", "name": "CCAAT/enhancer-binding protein epsilon", "aln": "---MSHGTYYECEPR---------------------------------------GGQQPLEFSGGRAGP-----------GELGDMCEHEASIDLSAYIESG--------------------------------EEQLLSDLFAMKPTP-EARSLKG------------PGTPSFP--HYLPADPR--PFAYPSHTFGPDRKALGPGIYSNPGS-----------YDPRAVAVKEEPRGPEGNRGTGRG---SYNP----------------------LQYQVAHCGQTAVHLPP-TLAAPGQPLR-VLKAPVAAAA------PPCSP--LLKAPSPAGP--------------SHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRIMETQQKVLEYMAENERLRSRVDQLTQELDTLRNLFRQIPEAASLIKGVG--GCS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PZD9-1", "uniprot_id": "CEBPE_MOUSE", "id": "Q6PZD9-1", "name": "CCAAT/enhancer-binding protein epsilon", "aln": "---MSHGTYYECEPR---------------------------------------GGQQPLEFSGGRAGP-----------GELGDMCEHEASIDLSAYIESG--------------------------------EEQLLSDLFAMKPTP-EARSLKG------------PGAPSFP--HYLPADPR--PFAYPSHTFGPDRKALGPGIYSNPGS-----------YDPRAVAVKEEPRGPEGNRGTSRG---SYNP----------------------LQYQVAHCGQTAVHLPP-TLAAPGQPLR-VLKAPVAAAA------PPCSP--LLKAPSPAGP--------------SHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRIMETQQKVLEYMAENERLRNRVDQLTQELDTLRNLFRQIPEAASLIKGVG--GCS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15744-1", "uniprot_id": "CEBPE_HUMAN", "id": "Q15744-1", "name": "CCAAT/enhancer-binding protein epsilon", "aln": "---MSHGTYYECEPR---------------------------------------GGQQPLEFSGGRAGP-----------GELGDMCEHEASIDLSAYIESG--------------------------------EEQLLSDLFAVKPAP-EARGLKG------------PGTPAFP--HYLPPDPR--PFAYPPHTFGPDRKALGPGIYSSPGS-----------YDPRAVAVKEEPRGPEGSRAASRG---SYNP----------------------LQYQVAHCGQTAMHLPP-TLAAPGQPLR-VLKAPLATAA------PPCSP--LLKAPSPAGP--------------LHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVG--GCS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21272-1", "uniprot_id": "CEBPB_RAT", "id": "P21272-1", "name": "CCAAT/enhancer-binding protein beta", "aln": "---MHRLLAWDAACLP--PPPA-----------------AFRPMEVANFYYEPDCLA--YGAKAARAAP-------RAPAAEP-AIGEHERAIDFSPYLEPLAPA---------------AADFAAPAPA----HHDFLSDLFADDYGAKPSKKPSDYG-------------------------------YVSLGRAGAK--AAPPACFP----------------PPPPAALKAEPGFEPADCKRADDAPA--------------------MAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKA------APAACFAGPPAAP-----------------AKAKAKKAVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEP--LLASAG--HC--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28033-1", "uniprot_id": "CEBPB_MOUSE", "id": "P28033-1", "name": "CCAAT/enhancer-binding protein beta", "aln": "---MHRLLAWDAACLP--PPPA-----------------AFRPMEVANFYYEPDCLA--YGAKAARAAP-------RAPAAEP-AIGEHERAIDFSPYLEPLAP----------------AADFAAPAPA----HHDFLSDLFADDYGAKPSKKPADYG-------------------------------YVSLGRAGAK--AAPPACFP----------------PPPPAALKAEPGFEPADCKRADDAPA--------------------MAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKA------APAACFAGPPAAP-----------------AKAKAKKTVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEP--LLASAG--HC--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17676-1", "uniprot_id": "CEBPB_HUMAN", "id": "P17676-1", "name": "CCAAT/enhancer-binding protein beta", "aln": "---MQRLVAWDPACLPLPPPPP-----------------AFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHERAIDFSPYLEPLGAPQ-APAPATATDTFEAAPPAPAPAPASSGQHHDFLSDLFSDDYGGKNCKKPAEYG-------------------------------YVSLGRLGAAKGALHPGCFAPLHPPP--------PPPPPPAELKAEPGFEPADCKRKEEAGAPGGGA--------------GMAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAKA------PPTACYAGAAPAPS---------------QVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEP--LLASSG--HC--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03484-1", "uniprot_id": "CEBPD_RAT", "id": "Q03484-1", "name": "CCAAT/enhancer-binding protein delta", "aln": "--MSAALFSLDSPARG-----------------------APWPTEPAAFYEPGRVGKPGRGPEPGDLGE---------PGSTTPAMYDDESAIDFSAYIDSMAA-----------------------VPTLELCHDEIFADLFNSNH------KAAGAG-------------------------------SLELLQGGPTR---PPGVGS-----------------IARGPLKREPDWGDGDAPG-----------------------------------SLLPAQVAVCAQTVVSLAAAAQPTPPTSPEPPRGSP------GPS-----LAPGPV---------------REKGAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLASLRQFFKELPSPP-FLPPTG-TDCR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00322-1", "uniprot_id": "CEBPD_MOUSE", "id": "Q00322-1", "name": "CCAAT/enhancer-binding protein delta", "aln": "--MSAALFSLDSPVRG-----------------------TPWPTEPAAFYEPGRVDKPGRGPEPGDLGE---------LGSTTPAMYDDESAIDFSAYIDSMAA-----------------------VPTLELCHDELFADLFNSNH------KAAGAG-------------------------------GLELLQGGPTR---PPGVGS-----------------VARGPLKREPDWGDGDAPG-----------------------------------SLLPAQVAVCAQTVVSLAAAAQPTPPTSPEPPRGSP------GPS-----LAPGTV---------------REKGAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLAGLRQFFKKLPSPP-FLPPTG-ADCR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49716-1", "uniprot_id": "CEBPD_HUMAN", "id": "P49716-1", "name": "CCAAT/enhancer-binding protein delta", "aln": "--MSAALFSLDGPARG-----------------------APWPAEPAPFYEPGRAGKPGRGAEPGALGE---------PGAAAPAMYDDESAIDFSAYIDSMAA-----------------------VPTLELCHDELFADLFNSNH------KAGGAG-------------------------------PLELLPGGPAR---PLGPGP-----------------AAPRLLKREPDWGDGDAPG-----------------------------------SLLPAQVAACAQTVVSLAAAGQPTPPTSPEPPRSSP------RQT-----PAPGPA---------------REKSAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLAGLRQFFKQLPSPP-FLPAAGTADCR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02637-1", "uniprot_id": "CEBP_DROME", "id": "Q02637-1", "name": "CCAAT/enhancer-binding protein", "aln": "MLNMESPQMYADAVQTLAQLDLKKEPPLQQATIGQITLTAMSTAQQQQQQQQQQQQQQQQQQQQQQQQPQQQTTDANNNTSQDAALLVKQHAMHQMQQVAALGSNNNLLQKQMLQQYSTQTDLDELTTQEITLDLQHLIDDQFRDTETLGIFSDMVTSPGGLS--ATLPPSGMVSAAAKVLQQQTLRNQHGYGGRGGGGGAGGALAYMPQPVHATYNNSSDENSSVGSDSSTIKEEPIDPEYRRHLQEAASQQAAFMGNGAGLYNGYGSGANGLTGGGNPLNGGNTTPSSNGSNGSTGSSNGSQFTNLTTANVLAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQ-QQHRKHSNKHVDKGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSLLKEKDALIRQLGEMTNELQLHKQIYMQLMNHANPEVSRVCRSFLNTNEHSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: ::. : . ..:: * * * :* ** : :. .:: :: : **: *************:*** * * :.:: . ::: * :: :::.:* : :: :: . ", "identical_positions": 28, "similar_positions": 45, "identity": "6.19%" }, { "cls_id": "homologset.agr.FB:FBgn0005640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7D0-1", "uniprot_id": "M0R7D0_RAT", "id": "M0R7D0-1", "name": "cyclin-dependent kinase", "aln": "-----------------------MG-QELCAKSRQPGCSCYHRSEGGE----------AHSCQR-------------------SQPGSTSEPAVFELTDLK---EASCSSASFHPRGLQAARVQKLESKR-----PRSNSDSFQEE-------------------------------------NLRQG--VPWKKSFPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQ-----HPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPPPEPQSLQTVWN--RLGGVP-EAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVELKPEMCDLS-ASYRKGHLLAGVNKCW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V3A1-1", "uniprot_id": "CDK15_MOUSE", "id": "Q3V3A1-1", "name": "Cyclin-dependent kinase 15", "aln": "-----------------------MG-QELCAKRLQPGCSCYHRSEGGE----------AHSCQR-------------------SQPGST-EPAVFELT------EASSSTASFHPRGLEAASAQKLKSKR-----PRSNSDSFQEE-------------------------------------NLRQG--LPWKKSLPFGAASSYLNLEKLGEGSYAKVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQ-----HPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPPPKPQSLQIVWD--RLGGVP-EAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVKLKPEMCDLS-ASYRKRHHLVGVNKCW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q40-1", "uniprot_id": "CDK15_HUMAN", "id": "Q96Q40-1", "name": "Cyclin-dependent kinase 15", "aln": "-----------------------MG-QELCAKTVQPGCSCYHCSEGGE----------AHSCRR-------------------SQPETT--EAAFKLTDLK---EASCSMTSFHPRGLQAARAQKFKSKR-----PRSNSDCFQEE-------------------------------------DLRQG--FQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQ-----HPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWN--RLGRVP-EAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLL-ASYQKGHHPAQFSKCW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLU9-1", "uniprot_id": "CDK15_DANRE", "id": "Q1RLU9-1", "name": "Cyclin-dependent kinase 15", "aln": "-----------------------------MQNLRHAASEAFQRLGLKQ----------RHLGYE-------------------ELGELD-------------------GVEKPQPHWFHTLQVRRLRVQR-----GRSNSDPMGGK-------------------------------------SFQQE--FQWKTGLQFGNATSYLNLEKLGEGTYATVYKGISRINGHLVALKVIHMKTEEGIPFTAIREASLLKGLKHANIVLLHDIIHTRESLTFVFEYVQTDLAQYMIQ-----HPGGLHSYNIRLFMFQLLRGLSYIHGRRILHRDLKPQNLLISYLGELKLADFGLARSKSIPCQTYSAEVVTLWYRPPDVLMGSTDYSTALDIWGAGCIFIEMLQGSPAFPGVADVFEQLLKIWTVIGVPTEEIWPGVSDLPNYKPEWFLPCKPQQFRDVWK--RLSQLPYKTEDLAQQMLMMNPKDRISAQDALLHPYFNTLPPPLMHLRDTVSIFKVPGVRLESEARDIFSPSRRTKTPLAPLAKCW-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O94921-1", "uniprot_id": "CDK14_HUMAN", "id": "O94921-1", "name": "Cyclin-dependent kinase 14", "aln": "----------MCDLI-EPQPAEKIG---KMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTR-------------------NCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESP-------------------------------------KVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDK-----HPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWN--KLSYVN-HAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35495-1", "uniprot_id": "CDK14_MOUSE", "id": "O35495-1", "name": "Cyclin-dependent kinase 14", "aln": "----------MCDLI-EPQPAEKIG---KMKKLRRTLSESFSRIALKKEDTTFDEICVTKMSTR-------------------NCQGTDSVIKHLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKSSSAGKESP-------------------------------------KVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDK-----HPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWN--KLSYVN-HAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A7V5-1", "uniprot_id": "A0A8I6A7V5_RAT", "id": "A0A8I6A7V5-1", "name": "Cyclin-dependent kinase 14", "aln": "-----MLLEQPCIAN-QYLSGETVCSGLPGQHMRGSFGCNAAAEPVHSAFLGTPQICVTKMSTR-------------------NCQGMDSVIKHLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKSSAAGKESP-------------------------------------KVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDK-----HPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWN--KLSYVN-HAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PD73-1", "uniprot_id": "A0A8M9PD73_DANRE", "id": "A0A8M9PD73-1", "name": "Cyclin-dependent kinase 14", "aln": "----------MCDLLPAAQPVQKIG---KMKKLRRTLSESFSRIAFKKEDGGFDEICVTKMSTR-------------------SCQGSDSVIKPLDTIPEDKKVRVQRTQSGFEAFDKPASQVKRVHSENNACINAKSSSSGKESP-------------------------------------KLRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDK-----HPGGLQPDNVRLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTDYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPSEETWPGVHSLPHFKPDRFTVYSPKKLRQAWN--KLGYVD-HAEELASRFLQCFPKKRLSAQAALHHEYFSHLPSRLWELPDMSSIFTVAGVKLQSESGDSS----KSNSHGRGTANSKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17157-1", "uniprot_id": "PHO85_YEAST", "id": "P17157-1", "name": "Cyclin-dependent protein kinase PHO85", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MSSSSQ------------------------------------------------------------FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDE-EQLKLIFDIMGTPNESLWPSVTKLPKYNPN-IQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "M9PE01-1", "uniprot_id": "M9PE01_DROME", "id": "M9PE01-1", "name": "cyclin-dependent kinase", "aln": "MATTTTTTTTTGATNAKDGVTMREKKGGALQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHRGGHGGHHNHGNKVPYNGYNSEEYLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDRVQRQLSVSSDSKLLDEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEK-----HPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFP-RLYDIIEG--ETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGVQLYTEPNRQNKXKLKQVLSVDGVRFYC-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :** **:*:**.**** .: . **** : :. *** * ***** **:* *** *** *:*::**.:.**:***::..** :** . * **. :: * :***:**:: * . :****:******:. *:***.******: .:* :*:* ********.**.*:*: **: :*:*. ***: **. * . *** : :** *: ::*.*.*. **.* :* ::*. : .:.: : : :* * *:.*. ** * :* ", "identical_positions": 123, "similar_positions": 81, "identity": "22.49%" }, { "cls_id": "homologset.agr.FB:FBgn0005642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P39933-1", "uniprot_id": "TF3A_YEAST", "id": "P39933-1", "name": "Transcription factor IIIA", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGEVLNNEGMPLAELKQETIPISRSESSESLNSLTSTRSSSSNRPKTYFCDYDG-------------------------------CDKAFTRPSILTEHQ-LSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTH---TKS--FICPE--------------------------EGCNLRFYKHPQLRAHILSVHLHK-LTCPHCNKSFQRPYRLRNHISKHHDPEVENPYQCTFAG-------------------------------------------------------------------CCKEFRIWSQLQSHIKNDHP------------------------------------KLKCPICSKPCVGENGLQMHMIIHD---------------------------------DSLVTKNWKCHICPDMSFSRKHDLLTHYGSIHTEEDIPLELKYKISDIQQLVQDHGVQLGNSKHSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVD---LEKRLESGENGLN-----------------------------LLLNTVGRKYR----------------CFYNNCSRTFKTKEKYEKHIDKHKVHELKLKILQEKEE------------------NKTLVDQNHKEPFIIQKETQSAGDK-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9NQV6-3", "uniprot_id": "PRD10_HUMAN", "id": "Q9NQV6-3", "name": "PR domain zinc finger protein 10", "aln": "MDSKDESSHVWPTSAEHEQNAAQVHFVPDTGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPGQVAYVQQDATAQQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRLELQNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIH---INDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVASATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BU19-1", "uniprot_id": "ZN692_HUMAN", "id": "Q9BU19-1", "name": "Zinc finger protein 692", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSPAVDVSCRRREKRRQLDARR------------SKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSG--------CVLCAGPEPLPPKGLQYLVLLSHAHSRECSLVPGLRGPGGQDGGLVWECSAGHTFSWGPSLSPTPSEAPKPASLPHTTRRSWCSEAT----------------------------------SGQELADLESEHDERTQEARLPRRVGPPPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEPDAPRLLPSP--------------------------------VTCTPKEGETPPAPAALSSPLAVPALSASSLSSRAPPPAEVRVQPQLSRTPQAAQQTEALASTG---------------------------------------------------------------SQAQSAPTPAWDEDTAQIGPKRIR---------------------------KAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQH--------------------------------------IHQKSFSCPEPACGKSFNFKKHLKEHMKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHQRKHAETVAA---LRFPCEFCGKRFE----------------------------------------------------------KPDSVAAHRSKSHPALLLAPQESPSGPLEPCPSISAP-----------------GPLGSSEGSRPSASPQAPTLLPQQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15619-1", "uniprot_id": "SRYC_DROME", "id": "P15619-1", "name": "Serendipity locus protein H-1", "aln": "--------------------------MEGGKGEGKRMKEEAPSKKLPPKIYGGDAGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSSDVCRDDLAATSSSTVPSTLTSDNHSSSEFSVTFLRPEPPNAFTNSPFKKTSSSGTSTPVKLSPEQLHQQHQLQMPQSQLLQRKPKLPAATAVRLKVFKEEPPEEKHPPEQVVTKVEVCESELLP-----------------------------------------------------PSFTIFQQAKSAESVADAASMPPPAASETKPLEVDPAPLHKCLDCNG------------LLLETPDEVAKHEAAAHRLRLTYRCSECQREFELLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTR-------------------------SYRCEKCGKMYKTERCLKVHNLVHLEQ--RPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLEN-------------------------IPSYCSKKSTTNKAQKAAAAAAAAAAASSAVNPNELSASSELKAKANLTSTAAPAPAKQARKKKQP--------------------------------------------------------------QQATLAALGITLPAGTALQQVHPVP------------------LAQQHQQELTTVLVPLAPPAPKQTKAKRERKQLAPKQLQQKPQLLQQGQPQQS-----------------SLEPIPAVPQIKKEPVQTQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDAPNANTEMGTSDNAISDSAAALHFQIKNELPDELLPDDDFLPCKPSDRLPCPSLESSPFSSPASMELTAVSCASS--------------------VAISTNALPVR-----------------SGNYYLPAFTLNAHGKLSSTGNGVQSVTTSLAQTPSVSMVNVPLLVRSNQMLPSVDTLLFTNQTGGSRFFAGKSATAATPHLT----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . .: . : * : . ... . . .. . .:: : . . : : : * : . : : :. .: . . . . . . : * :. : . : : . . . . : : ", "identical_positions": 4, "similar_positions": 53, "identity": "0.35%" }, { "cls_id": "homologset.agr.FB:FBgn0005648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BNE4-1", "uniprot_id": "EPAB2_RAT", "id": "B0BNE4-1", "name": "Embryonic polyadenylate-binding protein 2", "aln": "------------------MWPSLSNELFPPP--------------TEVWLQTVSSDPEAQGWGAWGRTEKTSLVPSAGS----DKEAEENE-----DSSFLLSLLEPENLAKSPVYNQELEAIRLKLWTMEHAEVLPEPPSVQRKATEEERAEARELLSPETIGCFFPGAPKENVEADHRSVYVGNVDYGGSAAELEAYFSPCGEIHRVTILCDKFSGHPKGYAYIEFASKSSVQAAVRLDESTFRGRVIKVLPKRTNFPGIS----STDRGGLRTHSSSR-AAFL-QGSLQRKPRLRPHGQS---RGRGRASPWFSPY-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XFR0-1", "uniprot_id": "EPAB2_MOUSE", "id": "Q5XFR0-1", "name": "Embryonic polyadenylate-binding protein 2", "aln": "------------------MEPYLSNELFPPP--------------TEAWLQTVSSDPEAQGWGAWGRTEKTSLVPRAGSRAGSDKEAEENE-----DASFLLSLLEPENLAKSPVFNQELEAIKLKLWAMEHAEAQPEPPCVQRKATEEERAEVRQLLSPETVDCFFSRTSKENVEADHRSVFVGNVDYGGSAAELEAYFSPCGEIHRVTILCDKFSGHPKGYAYIEFASHRSVKAAVGLDESTFRGRVIKVLPKRTNFPGIS----STDRGGLRTHSGNR-AAFL-HGSLHRKARLRAHGRS---RGHGGAPQWFSPY-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDY0-1", "uniprot_id": "EPAB2_HUMAN", "id": "A6NDY0-1", "name": "Embryonic polyadenylate-binding protein 2", "aln": "------------------MWPFPSRSLFPPP--------------TQAWLQTVSSDPEAQGWGAWN-ETKEILGPEGGEGKEEKEEEEDAEEDQDGDAGFLLSLLEQENLAECPLPDQELEAIKMKVCAMEQAEGTPRPPGVQQQAEEEEGTAAGQLLSPETVGCPLSGTPEEKVEADHRSVYVGNVDYGGSAEELEAHFSRCGEVHRVTILCDKFSGHPKGYAYIEFATKGSVQAAVELDQSLFRGRVIKVLPKRTNFPGIS----STDRGGLRGHPGSRGAPFP-HSGLQGRPRLRPQGQN---RARGKFSPWFSPY-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CCS6-1", "uniprot_id": "PABP2_MOUSE", "id": "Q8CCS6-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELL----PEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEADPGDGAIE-DPELEAIKARVREMEEEAE-------KLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRSRYRARTTNYN-SSRSRFYSGFNSRPRGRIYRGRARATSWYSPY-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7Z8-1", "uniprot_id": "G3V7Z8_RAT", "id": "G3V7Z8-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGDPGGAGDYGNGLESEELEPGELL----PEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVETDPGDGAIE-DPELEAIKARVREMEEEAE-------KLKELQNEVEKQMNMSPPPGNAGPVIMSLEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRARYRARTTNYN-SSRSRFYSGFNSRPRGRIYRGRARATSWYSPY-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86U42-1", "uniprot_id": "PABP2_HUMAN", "id": "Q86U42-1", "name": "Polyadenylate-binding protein 2", "aln": "MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEAGEGAPGGAGDYGNGLESEELEPEELLLEPEPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGAIE-DPELEAIKARVREMEEEAE-------KLKELQNEVEKQMNMSPPPGNAGPVIMSIEEKMEADARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIKVIPKRTNRPGIS----TTDRGFPRARYRARTTNYN-SSRSRFYSGFNSRPRGRVYRGRARATSWYSPY-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KNF2-1", "uniprot_id": "PABP2_DROME", "id": "Q7KNF2-1", "name": "Polyadenylate-binding protein 2", "aln": "-----------------------------------------------MADEDITLNEDQLL-------ESLEETN------------------GEQETEIATEVEE----EGSMQIDPELEAIKARVKEMEEEAE-------KIKQMQSEVDKQMAGGSTTG-LATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLS----TTNR-FARGSFRGRGAR---VSRACCHSTFRGARRAMGYRGRA---NYYAPY-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QC75-1", "uniprot_id": "A0A8M9QC75_DANRE", "id": "A0A8M9QC75-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------MDES------------DMQYEVERQFPYS--PEAELFFDMTHEERIDSDRRSIYVGNVDYGATADELEMYFNSCGHVNRVTIPYNRFTGHPKGFAYIEFSDRESVRTAMALDETLFRGRVIKVSPKRTNIPGFS----TTDVYLRGGWSRGRGVR------ASRFNPFRGCRFIRSVLPTYNTTSCHVEN-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40561-1", "uniprot_id": "SGN1_YEAST", "id": "P40561-1", "name": "RNA-binding protein SGN1", "aln": "--------------------------------------------------------------------------------------------------------------MSQEEKVDAKATLKTEISNNKKNDKQ------ELELDELVGKLSIEGTPQVSQKLSKEEKHAHQLEADSRSIFVGNITPDVTPEQIEDHFKDCGQIKRITLLYDRNTGTPKGYGYIEFESPAYREKALQLNGGELKGKKIAVSRKRTNIPGFNRHYNSQNQYFQQWQWNYPLMAYPNPDTFPYYPPYPPNQSPNQNFGYNKNNYYRSPYNNKNRTFQKKHFNSAKDSTKNIRSTSQKPVVMPSDNVKSSTQEKDSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : .. : * **::***: . :. ::* :* ** ::*:*: :: * ***:.**** . :: :: ::*: * * **** **:. : : ", "identical_positions": 29, "similar_positions": 35, "identity": "7.92%" }, { "cls_id": "homologset.agr.FB:FBgn0005649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQH6-1", "uniprot_id": "A0A8I6AQH6_RAT", "id": "A0A8I6AQH6-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "-------------------------------------------------------------------MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDQ------------------TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQ-KKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE------------------SNTKQLSYDEVVSQSSPGNCTVYCGGVTS-GLTEQLMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLD----------------------------------------MINP---------------VQQQNQIGYPPAYGQWGQWYG-----NAQQIGQYVPNGWQVPAY--------GMYGQPWSQQGFNQTQS-SAPWMGPNYSVP------PPQGQNGG--MLPNQPAGYRVAGYETQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52912-1", "uniprot_id": "TIA1_MOUSE", "id": "P52912-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "-------------------------------------------------------------------MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-------------------TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQ-KKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE------------------SNTKQLSYDEVVSQSSPNNCTVYCGGVTS-GLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLD----------------------------------------MINP---------------VQQQNQIGYPPTYGQWGQWYG-----NAQQIGQYVPNGWQVPAY--------GVYGQPWSQQGFNQTQS-SAPWMGPNYSVP------PPQGQNGS--MLPSQPAGYRVAGYETQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31483-1", "uniprot_id": "TIA1_HUMAN", "id": "P31483-1", "name": "Cytotoxic granule associated RNA binding protein TIA1", "aln": "-------------------------------------------------------------------MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-------------------TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQ-KKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE------------------SNTKQLSYDEVVNQSSPSNCTVYCGGVTS-GLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLD----------------------------------------MINP---------------VQQQNQIGYPQPYGQWGQWYG-----NAQQIGQYMPNGWQVPAY--------GMYGQAWNQQGFNQTQS-SAPWMGPNYGVQ------PPQGQNGS--MLPNQPSGYRVAGYETQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70318-1", "uniprot_id": "TIAR_MOUSE", "id": "P70318-1", "name": "Nucleolysin TIAR", "aln": "------------------------------------------------------------------MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRR--VNSSVGFSVLQHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQ-KKDTSN-----------HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE------------------TNTKQLRFEDVVNQSSPKNCTVYCGGIAS-GLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPD----------------------------------------MTKN---------------FQQ---VDYS-QWGQWSQVYG-----NPQQYGQYMANGWQVPPY--------GVYGQPWNQQGFGVDQSPSAAWMG-GFGAQ------PPQGQAPPPVIPPPNQAGYGMASFPTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJN3-1", "uniprot_id": "Q5BJN3_RAT", "id": "Q5BJN3-1", "name": "Nucleolysin TIAR", "aln": "------------------------------------------------------------------MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRR--VNSSVGFSVLQHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQ-KKDTSN-----------HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE------------------TNTKQLRFEDVVNQSSPKNCTVYCGGIAS-GLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPD----------------------------------------MTKN---------------FQQ---VDYS-QWGQWSQVYG-----NPQQYGQYMANGWQVPPY--------GVYGQPWNQQGFGVDQSPSAAWMG-GFGAQ------PPQGQAPPPVIPPPNQAGYGMASFPTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01085-1", "uniprot_id": "TIAR_HUMAN", "id": "Q01085-1", "name": "Nucleolysin TIAR", "aln": "------------------------------------------------------------------MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMIT-------------------EHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQ-KKDTSN-----------HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE------------------NNTKQLRFEDVVNQSSPKNCTVYCGGIAS-GLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPD----------------------------------------MTKN---------------FQQ---VDYS-QWGQWSQVYG-----NPQQYGQYMANGWQVPPY--------GVYGQPWNQQGFGVDQSPSAAWMG-GFGAQ------PPQGQAPPPVIPPPNQAGYGMASYQTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJJ0-1", "uniprot_id": "E9QJJ0_DANRE", "id": "E9QJJ0-1", "name": "Nucleolysin TIAR", "aln": "-------------------------------------------------------------------MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQSDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQ-KKDTSN-----------HFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQD------------------NSAKQLRFDEVVNQSSPQNCTVYCGGIQS-GLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPD----------------------------------------MAKN---------------VQP---MEYG-QWGQWNQMYG-----NPQQYGQYMTNGWQVPSY--------GMYGQTWNQQGFGVEQSQSPAWVG-GFGTQ------PSQAQPG----AVMNQANFGMAGYQTQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMX4-1", "uniprot_id": "Q8IMX4_DROME", "id": "Q8IMX4-1", "name": "", "aln": "--------------------------------------------------------------------MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIRE--------------------PGNDPYAFIEYSNYQAATTALTAMNKRLFLEKEIKVNWATSPGNQPKTDISS-----------HHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAANAAVAAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYAYQQMGYWYPPATYPTTQMQTQYMQQGYYPYAYPTSAQQAGGVPCIQFSAAGYRMVPP-NVAWGVPGTVVPGVTAAAASAAAAANGSLAPQMMYSAAMPQYQTQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32588-1", "uniprot_id": "PUB1_YEAST", "id": "P32588-1", "name": "Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1", "aln": "MSENNEEQHQQQQQQQPVAVETPSAVEAPASADPSSEQSVAVEGNSEQAEDNQGENDPSVVPANAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIANIKIMIDK------------------NNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQSQQSSSDDTFN--------------LFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWAAKRDNNNNNNYQQRRNYGN--------NNRGGFRQYNSNNNNNMNMGMNMNMNMNMNNSRGMPPSSMGMPIGAMPLPSQGQPQQSQTIGLPPQVNPQAVDHIIRSAPPRVTTAYIGNIPHFATEADLIP-------------------------------------LFQN---------------------FGFILDFKHYPEKGCCFIKYDTHEQAAVCIVALANFPFQ-----------GRNLRTGWGKERSNFMPQQQQQGGQP------LIMNDQQQPVMSEQQQQQQQQQQQQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.******. ::* :: * ** . *:: * *.*:*: : : * ** ::* : : : :*:*** . .. . * . :*****. :: : :: ** * . ::: * * .*:**.**** .: :*:**: * ** :..* :* **:::: .. . . :: :: . . * .: . . :. * : : : : .: .: . ::. * * . . : : . : : : : : .: . .: *: . . ", "identical_positions": 56, "similar_positions": 101, "identity": "9.82%" }, { "cls_id": "homologset.agr.FB:FBgn0005655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04961-1", "uniprot_id": "PCNA_RAT", "id": "P04961-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLIQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVSIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17918-1", "uniprot_id": "PCNA_MOUSE", "id": "P17918-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLIQGSILKKVLEALKDLINEACWDVSSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVIKMPSGEFARICRDLSHIGDAVVISCAKNGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVHLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12004-1", "uniprot_id": "PCNA_HUMAN", "id": "P12004-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTP1-1", "uniprot_id": "PCNA_DANRE", "id": "Q9PTP1-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLVQGSILKKVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRNLAMGVNLSSMSKILKCAGNEDIITLRAEDNADALALVFETLNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVKFSASGELGTGNIKLSQTSNVDKEDEAVTIEMNEPVQLIFALNYLNFFTKATPLSKTVTLSMSADIPLVVEYKIADMGHVKYYLAPKIDEESS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17917-1", "uniprot_id": "PCNA_DROME", "id": "P17917-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNET-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15873-1", "uniprot_id": "PCNA_YEAST", "id": "P15873-1", "name": "DNA sliding clamp PCNA", "aln": "MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKS-GFLQFFLAPKFNDEE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:: :.:::*::::.:** : . :: ...*: *::*.*:* **.* : :.*: :***: :::*::* *::***:*..* * :*: *::..*:: ::** :::::::*.:***::* : * * * ::...: :*: **::* ***:::.::: * :*: :** *.*::*...: : .::: : :: :**::** * *. .** : *.:.** * : :.:: * :.:: : . *.::::****::::. ", "identical_positions": 72, "similar_positions": 130, "identity": "27.59%" }, { "cls_id": "homologset.agr.FB:FBgn0005658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4Z8P1-1", "uniprot_id": "Q4Z8P1_RAT", "id": "Q4Z8P1-1", "name": "", "aln": "----------------------MDGTIKEALSVVSDDQSLFDSAYGA------AAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ-PVRVNVKREYD--HMNGS-RESPVDCSVS--KCNKLVGGGEANPMNYNSYMDE-----KNGPPPPNMTTNERRVIVPA-----DPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMSKEDFLRATSLYNTEVLLSHLSYLRESS-----------------------------LLAYNTPSHTDQSSRLNVKEDP-SYDSV-RRGGWSNNMNSGINKSPPLGGAQSMGKNTEQ-RPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPT----------------ETSMYKYPSDISYMPSYHAHQQKVNFVQPHPSSMPVTSSSFFGAASQ-YWTSPTAGIYPNPSVPRHPN----THVPSHLGSYY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26323-1", "uniprot_id": "FLI1_MOUSE", "id": "P26323-1", "name": "Friend leukemia integration 1 transcription factor", "aln": "----------------------MDGTIKEALSVVSDDQSLFDSAYGA------AAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ-PVRVNVKREYD--HMNGS-RESPVDCSVS--KCNKLVGGGEANPMNYNSYMDE-----KNGPPPPNMTTNERRVIVPA-----DPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATSAYNTEVLLSHLSYLRESS-----------------------------LLAYNTTSHTDQSSRLNVKEDP-SYDSV-RRGAWNNNMNSGLNKSPLLGGSQTMGKNTEQ-RPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPT----------------ETSMYKYPSDISYMPSYHAHQQKVNFVPSHPSSMPVTSSSFFGAASQ-YWTSPTAGIYPNPSVPRHPN----THVPSHLGSYY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01543-1", "uniprot_id": "FLI1_HUMAN", "id": "Q01543-1", "name": "Friend leukemia integration 1 transcription factor", "aln": "----------------------MDGTIKEALSVVSDDQSLFDSAYGA------AAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ-PVRVNVKREYD--HMNGS-RESPVDCSVS--KCSKLVGGGESNPMNYNSYMDE-----KNGPPPPNMTTNERRVIVPA-----DPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYNTEVLLSHLSYLRESS-----------------------------LLAYNTTSHTDQSSRLSVKEDP-SYDSV-RRGAWGNNMNSGLNKSPPLGGAQTISKNTEQ-RPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPT----------------ESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQ-YWTSPTGGIYPNPNVPRHPN----THVPSHLGSYY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLW9-1", "uniprot_id": "A0A8M9PLW9_DANRE", "id": "A0A8M9PLW9-1", "name": "", "aln": "----MTMFQTVPDTSSYVKVRHHRHHEQEALSVVSEDQSLFEPPYAA------AAPLPKTDMTASGTQDYGQTHKINPIPPQQEWINQ-PVRVNVKREYD--HINGS-RESPVDCSVG--KCNKMVGGTEASQMNYTGYMDE-----KCAPPP-NMTTNERRVIVPAGEYCINPSLWSPDHVRQWLDWAIKEYGLQEIDTAMFHSTDGKELCKMSKDDFLRLTSVYNTEVLLSHLNYLRESSS----------------------------SISYNTPSHADQSPRLAAKDDA-SYDAV-RRTGWSNNMHSG--KGSPTVVSQSVSKNPDQPRPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANAGCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPT----------------ESTMYKYPSELPYVPSYHAHQQKVNFVSPHPPSMPVTSSNFFGPTTP-YWSSPPGGIYPNPSVPRHAN----SHVPSHLGSYY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A3D6-1", "uniprot_id": "D4A3D6_RAT", "id": "D4A3D6-1", "name": "", "aln": "------MIQTVPD---------PEAQIKEALSVVSEDQSLFECAYG-------TPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGS-RNSPDECSVT--KGGKMVGSPDTVGMSYGSYMEE-----KHMPPP-NMTTNERRVIVPA-----DPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDL-PYEPP-RRSTWTGHSHPTPQSKAAQPSPSTVPKTEDQ-RPQLDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPP----------------ESSLYKYPSDLPYMGSYHTHPQKMNFVAPHPPALPVTSSSFFATPNP-YWNSPTGGIYPN---TRLPA----SHMPSHLGTYY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81270-1", "uniprot_id": "ERG_MOUSE", "id": "P81270-1", "name": "Transcriptional regulator ERG", "aln": "------MIQTVPD---------PAAHIKEALSVVSEDQSLFECAYG-------TPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQAPARVTIKMECNPSQVNGS-RNSPDECSVN--KGGKMVGSPDTVGMSYGSYMEE-----KHVPPP-NMTTNERRVIVPA-----DPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDL-PYEPP-RRSAWTGHSHLTPQSKAAQPSPSAVPKTEDQ-RPQLDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPP----------------ESSLYKYPSDLPYMGSYHAHPQKMNFVSPHPPALPVTSSSFFASPNP-YWNSPTGGIYPN---TRLPA----SHMPSHLGTYY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11308-4", "uniprot_id": "ERG_HUMAN", "id": "P11308-4", "name": "Transcriptional regulator ERG", "aln": "----------------------MASTIKEALSVVSEDQSLFECAYG-------TPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGS-RNSPDECSVA--KGGKMVGSPDTVGMNYGSYMEE-----KHMPPP-NMTTNERRVIVPA-----DPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDL-PYEPP-RRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQ-RPQLDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPP----------------ESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNP-YWNSPTGGIYPN---TRLPT----SHMPSHLGTYY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATP1-1", "uniprot_id": "A0A8M3ATP1_DANRE", "id": "A0A8M3ATP1-1", "name": "", "aln": "------MAGRSRGR------WLYGANKKEALSVVSEDQSIFESPFS-------GPQAMHMKAEIGSPAVFRQASEESIEPTEPDWSGS-AAQNSAKRAEH---INGTSHESPVDCSVT--KRTRHMSNSDGGQLSYQASYPEPRSSPQTATPP-SSTTEEKRVIVPA-----DPEVWTQDHVRQWVDWAIKEYALSDVDVSLFQTLDGKALCKLSKEDMMRITSAYNTDILLSHLNYLRESSP---------------------------TFSYPTNPTNTQPQPRVQVKAAENSFEEIGRRNSWSSSGLPAVPKGSPIEHQHNTRITEPPPRLPQDPYQALGSISSRLANPEAKPIHTKNRTTKQNSSHLPVSSTDRTVGSGQIQLWQFLLELLSDSNNSTIITWEGTNGEFKMTDPDEVAKRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGISQSHQNHST----------------EGSVYKFQTEGSYMQSYHSHQPKMNFISPHSTPMSVTTSNFFTPQST-YWNSATSVVYPSSPMPRHPS----THT--HLNTYY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8QZW2-1", "uniprot_id": "FEV_MOUSE", "id": "Q8QZW2-1", "name": "Protein FEV", "aln": "----------------------------------------------------------------------------------------------------------------------------MRQSGTSQPLLINMYLPD---------P---------------------------------------------VGDGLFK--EGK-------------------------------------------------------------------SPSWGPLSPAVQK-------------------------------------------------------------------------------------------GSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQPPPAHAHAAAAAAAAAAAAQDGALYKLPAGLAPLP--FPGLSKLNLMAASAGVAPAGFSYWPGPNAT-AAAAATAALYPTPGLQPPPGPFGAVAAASHLGGHYH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29774-1", "uniprot_id": "ETS3_DROME", "id": "P29774-1", "name": "DNA-binding protein D-ETS-3", "aln": "MYENSCSYQTALDLKRVSPPTLAQVKTEECLALGQCSPEWTSYRFHQSTFEQLKQSVEKAKAALQDRSSFFGASSAFSDIYSSQRLTDSLDTLPVQSGNGGGNCLGLPHNPNVGVGVAGVLNYNAVSSSTAGVLSSSGNGVQRHRLDTLQPPSGCSPAVTQHGVITS---------SAGQVTSGTLDAVSAAPALPSLTASSSSHVEHKVRADKSTLDCATTSSHAAAPSSSSSASDHQQGR-------------------------------ISGSKSSNTSGTGGGASASGGGGSALYSSYKSSWGSHSSTQSQGYSSNALGIKHDPHSQLRQPDPYQMFGPTSSRLASS----------------------------GSGQIQLWQFLLELLSDSNNASCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGLAAATQPAAS-----------------DPTYKYQSDL-FMTPYHHSAKLSSFMSPHHGMTSSSASIFPSAASWGNWGSPATNLYQPHSMSHVTP----SHVAPHLSSYPHYA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * : : * . ***************:* *: *:*** :****:*******:*****************************:*********:***:*:: : * .. . ** : : . .:: . . * : . :.. :* . **. : ", "identical_positions": 83, "similar_positions": 38, "identity": "14.31%" }, { "cls_id": "homologset.agr.FB:FBgn0005659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYE0-1", "uniprot_id": "B2RYE0_RAT", "id": "B2RYE0-1", "name": "SAM pointed domain-containing Ets transcription factor", "aln": "-----------------------------------------------------------------------------MGSASPGLSNVSPG-CLLLSPDVALRTGVEKAASG-------AMGLEKQEWSPSPPATPEQGLSAFYLS---YFN-MYPEDGSWVAKVPEASAREDHPEEPE-------------------QCP--VIDSQASGN---------TLDEHS--------------------LEQVQSMVVGEVLKDIETACKLLNITADPGDWSPGNVQKWLLWTEHQYRLPPAGKAFQELGGK--ELCAMSEEQFRQRAPLGGDVLHAHLDIWKS------AAWMKERTSPGALHYCAATHPARPGFLPASTSEEG--------------WTDGEVDSSCS------------------GQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTP3-1", "uniprot_id": "SPDEF_MOUSE", "id": "Q9WTP3-1", "name": "SAM pointed domain-containing Ets transcription factor", "aln": "-----------------------------------------------------------------------------MGSASPGLSNVSPG-CLLLFPDVAPRTGTEKAASG-------AMGPEKQEWSPSPPATPEQGLSAFYLS---YFN-MYPDDSSWVAKVPEARAGEDHPEEPE-------------------QCP--VIDSQASGS---------TLDEHS--------------------LEQVQSMVVGEVLKDIETACKLLNITADPGDWSPGNVQKWLLWTEHQYRLPPAGKAFQELGGK--ELCAMSEEQFRQRAPLGGDVLHAHLDIWKS------AAWMKERTSPGTLHYCAS------------TSEEG--------------WTDGEVDSSCS------------------GQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95238-1", "uniprot_id": "SPDEF_HUMAN", "id": "O95238-1", "name": "SAM pointed domain-containing Ets transcription factor", "aln": "-----------------------------------------------------------------------------MGSASPGLSSVSPS-HLLLPPDTVSRTGLEKAAAG-------AVGLERRDWSPSPPATPEQGLSAFYLS---YFDMLYPEDSSWAAKAPGASSREEPPEEPE-------------------QCP--VIDSQAPAGSLDLVPGGLTLEEHS--------------------LEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAGK--ELCAMSEEQFRQRSPLGGDVLHAHLDIWKS------AAWMKERTSPGAIHYCAS------------TSEES--------------WTDSEVDSSCS------------------GQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29775-1", "uniprot_id": "ETS4_DROME", "id": "P29775-1", "name": "DNA-binding protein D-ETS-4", "aln": "MEYEKMLYMPAASEMPHSPQLKPHQFQAHTPTDQYSSYADNFDLSLLPQESASIPTTVFQYNAPQIKVECAWDSQPIQQQQQPTAPYTNPSSHQLIPPPAYPHSAYPSPQSSPLQSEFAAYGLGRFGGSYDSLNSPSPSLEAVSIKQELHILPPSPPESNCETPSPRSSCGESIKAEPLDADIESLIDLNSLLQQQSLQSPQNLQDTKPDHQLLRECLEDTSFQKRHNLKPLALESFIGGLAEVRGDFEPVISLALEHAKREADAICAELQISQDPNGWSPAQVHAWLRSTLAQFRLPPVADLELHFCENGAALALLSEEEFVRRLPESGSTLHAQLEIWKMAYADQPAHQQHSQQSASTDHWPASYAMPHLDLDYNEDSEDDDDMEADAQVAPLNGSTTSPPATNASNGGTATVKRPNGGRTGGGGSHIHLWQFLKELLASPQVNGTAIRWIDRSKGIFKIEDSVRVAKLWGRRKNRPAMNYDKLSRSIRQYYKKGIMKKTERSQRLVYQFCHPYSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* . ..*. *: * . ::. .. :. * * : * .. :*. .*.*. :. :: * :.. : * : . *. ** *.* : *::. ::::: :* * *:.: .. :: :: * *:*: ** .***.:*: ** * *:**** .. .: : *. :***:* :* * .*..***:*:*** * :.: *..: *: *: **:. * . :..* *. *********** .*: * ***:::.*********.:**:*** ************************::*.: ******** ** ", "identical_positions": 127, "similar_positions": 103, "identity": "24.52%" }, { "cls_id": "homologset.agr.FB:FBgn0005660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4Z8P1-1", "uniprot_id": "Q4Z8P1_RAT", "id": "Q4Z8P1-1", "name": "", "aln": "------------------MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWIN--QPVRVNVKREYDHMNG-SRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNG----PPPPNMTTNERRVIVPA-----DPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMSKEDFLRATSLYNTEVLLSHLSYLRESS-LLAYNT-PSHTDQSSRLNVKEDP-SYDSV-RRGGWSNNMNSGINKSPPLGGAQSMGKNTEQ-RPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP----------------HPTETSMYK------YPSDISYMPSYHAHQQKVNFVQPHPSSMPVTSSSFFGAASQYWTSPTAGIYPNPSVPRHPN--------------THVPSHLGSYY-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26323-1", "uniprot_id": "FLI1_MOUSE", "id": "P26323-1", "name": "Friend leukemia integration 1 transcription factor", "aln": "------------------MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWIN--QPVRVNVKREYDHMNG-SRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNG----PPPPNMTTNERRVIVPA-----DPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATSAYNTEVLLSHLSYLRESS-LLAYNT-TSHTDQSSRLNVKEDP-SYDSV-RRGAWNNNMNSGLNKSPLLGGSQTMGKNTEQ-RPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP----------------HPTETSMYK------YPSDISYMPSYHAHQQKVNFVPSHPSSMPVTSSSFFGAASQYWTSPTAGIYPNPSVPRHPN--------------THVPSHLGSYY-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01543-1", "uniprot_id": "FLI1_HUMAN", "id": "Q01543-1", "name": "Friend leukemia integration 1 transcription factor", "aln": "------------------MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWIN--QPVRVNVKREYDHMNG-SRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNG----PPPPNMTTNERRVIVPA-----DPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYNTEVLLSHLSYLRESS-LLAYNT-TSHTDQSSRLSVKEDP-SYDSV-RRGAWGNNMNSGLNKSPPLGGAQTISKNTEQ-RPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP----------------HPTESSMYK------YPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPN--------------THVPSHLGSYY-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLW9-1", "uniprot_id": "A0A8M9PLW9_DANRE", "id": "A0A8M9PLW9-1", "name": "", "aln": "MTMFQTVPDTSSYVKVRHHRHHEQEALSVVSEDQSLFEPPYAAAAPLPKTDMTASGTQDYGQTHKINPIPPQQEWIN--QPVRVNVKREYDHING-SRESPVDCSVGKCNKMVGGTEASQMNYTGYMDEKCA----PPP-NMTTNERRVIVPAGEYCINPSLWSPDHVRQWLDWAIKEYGLQEIDTAMFHSTDGKELCKMSKDDFLRLTSVYNTEVLLSHLNYLRESSSSISYNT-PSHADQSPRLAAKDDA-SYDAV-RRTGWSNNMHSG--KGSPTVVSQSVSKNPDQPRPQPDPYQILGPTSSRLANP----------------------------GSGQIQLWQFLLELLSDSANAGCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP----------------HPTESTMYK------YPSELPYVPSYHAHQQKVNFVSPHPPSMPVTSSNFFGPTTPYWSSPPGGIYPNPSVPRHAN--------------SHVPSHLGSYY-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ATP1-1", "uniprot_id": "A0A8M3ATP1_DANRE", "id": "A0A8M3ATP1-1", "name": "", "aln": "--------MAGRSRGRWLYGANKKEALSVVSEDQSIFESPFSGPQAMHMKAEIGS-PAVFRQASEESIEPTEPDWSG--SAAQNSAKRA-EHINGTSHESPVDCSVTKRTRHMSNSDGGQLSYQASYPEPRSSPQTATPPSSTTEEKRVIVPA-----DPEVWTQDHVRQWVDWAIKEYALSDVDVSLFQTLDGKALCKLSKEDMMRITSAYNTDILLSHLNYLRESSPTFSYPTNPTNTQPQPRVQVKAAENSFEEIGRRNSWSSSGLPAVPKGSPIEHQHNTRITEPPPRLPQDPYQALGSISSRLANPEAKPIHTKNRTTKQNSSHLPVSSTDRTVGSGQIQLWQFLLELLSDSNNSTIITWEGTNGEFKMTDPDEVAKRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGISQSHQN----------------HSTEGSVYK------FQTEGSYMQSYHSHQPKMNFISPHSTPMSVTTSNFFTPQSTYWNSATSVVYPSSPMPRHPS--------------THT--HLNTYY-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70132-1", "uniprot_id": "FEV_RAT", "id": "O70132-1", "name": "Protein FEV", "aln": "---------------------------------------------------------------------------------------------------------------MRQSGTSQPLLINMYLPDPVG------------------------------------------------------------DG--LFKEGKS---------------------------------PSWGPLSPAVQK-------------------------------------------------------------------------------------------GSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQPPPAHAHAAAAAAAAAAAAQDGALYK------LPAGLAPLP--FPGLSKLNLMAASAGVAPAGFSYWPGPNATAAAAATAALYPTPGLQPPPGPFG----------AVAAASHLGGHYH------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29776-1", "uniprot_id": "ETS6_DROME", "id": "P29776-1", "name": "DNA-binding protein D-ETS-6", "aln": "----------MAILQNSRQSHKQLPIISQTIRSAWCQQRPINAMHQDVRQKSIGSGNETKLEAKETEVPTNRRRRRRRCSSSSTSDSSASSYSSTDSDSGSSTSSSSIRSQLPALNLPVPLPLATPTPPAVSSPHQAPSPRRNSSDSNRSVSPVEVPVDPHAWTPEDIASWVRWATRKFKLDPEPDIDRFPKDAQELCDLSRADFWVCAGSRRGGMLLAQHFAISLYH--------ATGRETSPMLNDDEPN--------------------------------------------PYQLLNAASHRLVAQG---------------------------SGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSYNHHAGGAMQLGRHPPPLHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSASTSNFTAPFQGGTAGVDPARTSTSSAGNYDQGPVTPTTNAFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZEY9-1", "uniprot_id": "D3ZEY9_RAT", "id": "D3ZEY9-1", "name": "ETS translocation variant 2", "aln": "-------------------------MDLWNWDEASVQEVPPGDKLTGLEGAEFGFYFPEVALQGDTPITPMNVESCWKG-------FPELDWNPALPHEEVPFEAEPVAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGFEG-----ATGQNTATSAGGVPSWSHPPATWSTASWDCSAGPNGSTYWDSGLGGEAQADYKMSWGGSAGSDYTTTWNSGLQN-CSIPFEGHQIPAFATPSKS--------------------------------------------SQQSDRATLTPYSKTN---------------------------HRGPIQLWQFLLELLHDGARSSCIRWTGNNREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPVLACQD-------------------------------------------------------------DMGHLPGAEGQ----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41163-1", "uniprot_id": "ETV2_MOUSE", "id": "P41163-1", "name": "ETS translocation variant 2", "aln": "-------------------------MDLWNWDEASLQEVPPGDKLTGLG-AEFGFYFPEVALQEDTPITPMNVEGCWKG-------FPELDWNPALPHEDVPFQAEPVAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGFEG-----ATGQNPATSAGGVPSWSHPPAAWSTTSWDCSVGPSGATYWDNGLGGEAHEDYKMSWGGSAGSDYTTTWNTGLQD-CSIPFEGHQSPAFTTPSKS--------------------------------------------NKQSDRATLTRYSKTN---------------------------HRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPVLAYQD-------------------------------------------------------------DMGHLPGAEGQ----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00321-1", "uniprot_id": "ETV2_HUMAN", "id": "O00321-1", "name": "ETS translocation variant 2", "aln": "-------------------------MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTA--TAETCWKGTSSSLASFPQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAGSEG-----AAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEP--------------------------------------------SPQSDRASLARCPKTN---------------------------HRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPD-------------------------------------------------------------CAGGGRGAETQ----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. . . . . * *********** * .: * * * **:: **.***: ***** **.***:****.***** ::*: * *::*:*:*. : : . . ", "identical_positions": 48, "similar_positions": 29, "identity": "8.51%" }, { "cls_id": "homologset.agr.FB:FBgn0005666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WZ42-1", "uniprot_id": "TITIN_HUMAN", "id": "Q8WZ42-1", "name": "Titin", "aln": "MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLETVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT--PDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMS----PARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQELQSILEQDKLTPESTREFLCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEEPETQAVLSDTEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVAEEVLSPKEKTVSDTNREQRVTLQKQEAQSALILSQSLAEGHVESLQSPDVMISQVNYEPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSDNVVMPPDQIIESKREPVAIKKVQEVQGRDLLSKESLLSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRHIMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMS-----FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK-------EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRK----YQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGK-DSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPRE----EIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYD-YKEFEEYEPTEEYDQYEEYEEREYERYEEHEEY----ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVR-VPEVPKELEPEEVAFEEEVVTHVEEYLVEEE----EEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALP---QEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE-----YVPEEEEFVPEEEVLPEVKPKVPVPAP--VPEIKKKVTEKKVVIPKKEEAP----------------------------PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEV--------EEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKK------VLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPK-GPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP-EEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKK------PVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPP--AVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK---------VIEKPKLK-------------------------------------------------PRPPPPPPAPPKEDVKEKIFQLKAIPKKK----------------VPEKPQVPEKVELTPLKVPGGEK------KVRKLLPERKPEP-KEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTK-RERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGE---TATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTK--HSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDE---VILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETET---ARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDD---AVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGG--VEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQD-KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-VPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE--LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEP-SDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPVTVKDQTCPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAG--IGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEG-TAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE-PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE-PTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP---LESV-AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSI-IVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGP---VTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGV----SKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWE-----KPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSG--EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR-KYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQ--RKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTR-----------------------AMNYDEEVDETREVSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKG-TDQVLVKKEISILNIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLRMPYDVPEPRKYKQTTIEEDQRIKQFVPMSDMKWYKKIRDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRITDQYRPKWRIPKLSQDDLEIVRPARRRTPSPDYDFYYRPRRR-SLGDISDEELLLPIDDYLAMKRTEEERLRLEEELELGFSASPPSRSPPHFELSSLRYSSPQAHVKVEETRKDFRYSTYHIPTKAEASTSYAELRERHAQAAYRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELDFMSKEEKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRS-HRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP--EPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTES----------------------------------------------------TVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG-GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISK--TKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSG---DTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ-GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZUN3-1", "uniprot_id": "A0A8I5ZUN3_RAT", "id": "A0A8I5ZUN3-1", "name": "Titin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRETTMTSSTQIRREERWEGRYGVQEQVTISGAAGTAASVSARSSFTAEAVTTGAKEVKQETDKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHVQPAQKQMRKEAEKTAVTKVVVAADKAKEQELRLRTREEIITKQEQTHIAHEQIRKETEKAFVPKVVISATKAKEQETRITGEITTKQ----------------------------------------------------------------------------------------------------------------------------------------EQKRITQETVGVGKKAEAVATVVAAVDQARVREPREPRHVEESYSQQTTLEYGYKEHISATKVPEQPQRPASEPHVVPKAVKPVVIQAPSETHIKATDQVGMHISSQVKKTTDISTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSTTSSTQKITKSVKAPTVKPGETRVRAEPTPSPKFPFADVPAPDTYKSQAGIEVKKEVGVSISGSTVREEQFELLRGREAKVTETARVPAPAEVPVTPPTLVSGLKNVTVVEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFDKETT-LTEKFTTEEKRFVESRDVVMTDTSITEEQAGPGEPAAPFFISKPVVQKLVEGGSVVFECQIGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLLEEADYEALIKSQQETLYQTQMSTFIQEPKVGEIAPGFAYSEYEKEYEKEQALIRKKMAKDTVMVRTFVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEERMAVDISESEAVESGFDIRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIRRGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPFSAPTYMPTPEAVSRIRSVSPRSVSRSPIRISPAMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPASFKCLEGQTARFDLKVVGRPMPETFWFHNGQQIVNDYTHKVVIKEDGTQSLIIVPALPSDSGEWTVVAQNRAGKSTISVTLTVEAVEHQIKPAFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGEAALKIDSTISQDSAWYTATAINKAGRDTTRCKVNIEVEFAEPEPERRLIIPRGTYRAKEISAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRLINEFGYCSLDYEAAYSRDSGVITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGKKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLFPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVTEHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEPGKLQFEVQKVDRPVDTGETKEVVKLKRAERITHEKVSEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLKKTKDELLHWTKELTEEEKKALAEEGKVTIPTFKPERIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGIEVHAGDKYRMHSDRKVHFLSVLTIDTSDAEDYSCVLVEDENIKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIISPENIEGKWYHNDVELKSNGKYSITSRRGRQNLTVKDVTKEDQGEYCFVVDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLENVEGVWMKDGQEVQHSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGNVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQSIVKGTKQRLVINRTHASDEGPYKLMVGRVETSCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVVWNFKGQEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGEYAFYAGENTTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPESEGEWLKDGKHLTLSNNFRSESDGHKRRLVIAAAKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLRNLTVTETQDAIFSVELTHPDVKGVQWIKNGVVLDSNDKYEISVKGTLYSLKIKNCAMADESVYGFKLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMRNIEVPETKAASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDGQELQIVDRIKIQKEKYVHRLLIPSARMSDAGKYTVVAGGNMSTANLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVEERHQYVVERRIHRMFISEARHSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVIAGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVTPLQDAVTSEGRPARFQCQVSGTDLKVSWYCRDKKIKPSRFFRMTQFEDTYQLEIAEAFPEDEGTYAFVANNAVGQVSSTATLRLEAPESILHEQIGQQIEMEMK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFLCTVSGTPVIETIWQKDGTALSPSPDCRITDADNKHSLELSNLTVQDRGVYSCKASNKFGADICQAELTIIDKPHFIKELEPVQSAINKKIHLECQVDEDRKVSITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYSCTASNEAGSSSSSATVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFANSEAILDITDVKVDDSGTYSCEATNDAGSDSCSTEVVIKEPPSFIKTLEPAHIVRGANALLQCEVAGTGPFEVSWFKDKKQIRSSKKYRLFTQKTFVFLEITSFNSADIGDYECVVANEVGKCGCVATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSSGVAVLTISDVQIGLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKEIAASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSRGALIVQEPPSFVTKPESRDVLPGSAVCLKSAFQGSTPLTIRWFKGDKELVSGGSCYITKEASESSLELYAVKTTDSGTYTCKVSNVAGSVECSANLFVKEPATFTEKLEPSQLLKKGDATQLVCKVTGTPPIKITWFANDRELRESSKHKMSFVESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTSIVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFIQDQLVSLQILKFVASDAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIETTSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASDKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPPYFVEKPQSQDVNPSTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRRYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCAPSDVGEYQCIIANEGGSCACTARVALKEPPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPINAQWFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNEHELTASDKYQMTFIDSVAVMQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPVVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHASIHILNVDSTDIGEYHCKAQNEVGSDTCICAIKLKEPPKFISKLNSLTVVAGEPAELQASIEGAPPISVHWLKEKEEVVRESENVRISFVNNVATLQFAKAEPANAGKYICQVKNDGGVRENMASLTVLEPAVIVEKAGSMTVTVGETCSLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDIGGVLGTSCVLECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEPLEILPGKNITFTSVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELELFNIDVSQSGEYTCVVSNNAGQASCTTRLFVKEPATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVVITPSERCNIVTTEKTCILEILTSTKGDAGHYSCEIENEAGRDSCDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVGINDSGEYTCVAENSIGTAASKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIHVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFIKKLDTSKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASVEDTGDYICEAHNGVGHASCSTALKVKAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKVTSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDVSTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASHSGKYVCQIKNDAGMRECSALLTVLEPARIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWLKDGRELSSGSRHHITFVRNLASLKIPSAEMNDKGLYSFEVENSVGKSSCTVSVHVSDRVVPPSFIRKLKDTTATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQPSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSALLTVQEPPSFEQTPDSVEVLPGMSLTFTSVFRGTPPFKVKWFKGSRELESGEACTISLEDFVTELELLEVEPLQSGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPIAVSWLKNEYPLSQSPNCGITTTERSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAIGEPTTLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGQLLKDDSNLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMS-----FEDSVAILEMHNLSVEDSGDYTCEARNAAGSASSSTSLKVK-------EPPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWYKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTLKAPPQFVKKLSDVSTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISHSENVATLHFSRAEPANAGKYTCQIKNDAGVQECYATLSVLEPATIVEKPESIKVTTGDTCTLECMVSGTPELSTKWFKDGKELTGDSKYKISFFNKVSGLKIISVAPGDSGVYSFEVQNPVGKDSCTVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVFGSPPISVLWLHDGNAISSGRK----YQTTLTDNTCALTVNMLEDADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKPDPMDVLTGSNVTFTSIVKGTPPFTVSWFKGSSELVPGARCNVSLQDSVAELELFDVDTSQSGDYTCIVSNEAGRASCTTQLFVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGVNVTASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGK-DSCSAQILILEPPYFVKQLEPLKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTCKMHFKNNVATLVFTQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNVQTSFLDNIATLNIFKTDRSLAGQYSCTVTNPIGSASSSAKLILTEGKNPPFFDIPLAPVDAVVGESADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAINEVGKDSCTAQLNIKERLTPPSFTKKLSETIEETEGNSFKLEGRVAGSQPITIAWYKNNVEIHPTSNCEITFKNNALLLQVKKASMADAGLYTCKATNDAGSALCTSSIVIREPKKPPVFDQHLTPVTASEGDFLQLSCHVQGSEPIRIQWLRAGREIKPSDRCSFSFASGTAVLELKDTAKADSGDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDESKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVSFIQQRLTQTEPVTLIKDIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPSNKYEITINGDRHTLRVRNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRVLKPQGRVKTEVEHKVHKLTIADVRAEDQGRYTCKHEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEIPPAVAPSIPLLLPLPEEKKPPAKRIEVTKKGVKKDTKKVVAKPKEEAPPPPPVPEVAKKPPPPTPMIPAKPSEIIDVSSKAEEVKITTITRKKEIHKEKEAVYERKEAVY-EKKVLIEPWEEPYEELETEPYTEPYEEPYYEEPDEDYEEIKVEAKKEVHEEWEEDYEEGQEYYEREEGYDEGEEEWEEIYHEREIIQVQKEVHEDLHEKKIPAKVPEKKVPPP-KVVKKPVVEKIEKTTRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEIIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEP---------------------------PKKPVPEEVVPVPIPKKVEPPAVKVPEAPKKPVPEEKKPVPIPKKEPAAPPKVPEAPKKPAPEEKTAVPVAKKKEAPPPKVTEVQKKVVTEEKITIIPQREESPPPAVPEIPKKKVPEEKRPVPRKEE-VPPPK---APPKKPVPEEVVPVPIP---KKAPPRAEVSKKTVVEEKKFAAEERLSMAVPQRVELMRHEE---EEWTYSEEEEQVSVSVYREEERDEEE-AEITEYEVLEEPEEYVVEEKLHVISKRVEVEPAKVPEKHEKKIIPRPKVPAKIEEPPPTKVPEPPKKMVPEKKVPAPPPK--KVPPAKAPEEPKKPVPERRVPAEVVEIEEPPPTKVTEKHMKITQEEKVLVAVTKKEEPPRARVPEEPKKVVPEEKFPKLKPRREEEPPAKVTEVRKRAVKEEKVSIEVPKREPRPTKEVTVTEEKKWSYTREEETVLEHREEEYEDYEDYEEYKEYEEYEPTEEYDQYDEYAERELEHYEEAKEQEEYVVPEPKKPITRKPA-QEPVPAKPKAPPPKVPKKAIPEEKAPLLIQKKLKPLPPKAPEEPKKVVEEKIQISITKREKQQVTEPVAKVPGVPKKREPEEVVIFKEEVEAHEEEYIVEEEEEYVHEEEYVHEEEYIHEEEYVHEEEYIHEEEEYLHEEEVIAEEEVLPVAPVKVPVVPKKPVPEEKKPVPVPKKKEAPPAKVPEIPKKPEEKVSVPVPKKEKAPPAKVPEVPKKPVPEEKAPVPVPKKVEPPPAKVPEVPKKPVPEKKVPAPTPKKVEAPPAKVPEVPKKPIPEEKKPTPLLKKMEAPPPKVPKKREVVPVPVALPREEEEEEAPFEEVTVPEEEILPEEE-VPPEEEEVLPEEEEVLPEEEEVPPEEEEALPEIKPKVPKPAPVPKKTVPEKKVPVPVAKKVEPPPPPKVPEIKKKVPEKKVVVPKKEEAPPTKVPVVPKKPEPEKKVPAPALKKAVVPPAKVPEVPKRVEEKRIVPPKEEEVPPAKVYEEAEEP--TPEETPEEPPSIEEEEIVEEEEEEEVPPPRAPEVVKKAVPAAPAPVPKKAEAPPTKVPKKIPEEKVPVPVQKKEAPPARVPEVPAKVPEKKKIPEKKVPVPKKEAVPPAKGKAVFEEKISVAYQQEERVQERIELELVEAQVEEAFEEEQFHEVQEYFEEEEFHEVEEFIRVEERRFQEEHKVEEVHRVIEFLEAEEVEVHEKPKIPPKKGPEVSEKVIPPKKPPTKVLPRKEPPAKAPEVTKKMVVEEKVRVPEEPKVPAPKAPEVPKKITPEEKVHEAVPKKPEAPPPKVPEVPKKIIQEEKLPVVLPEDTEIYIYEASEETVIEEEHVIHPQKARLKVAKAPAPPQTVVTEEKTYVTIRKTRETLAHTESETTREAFPELKSYEAVPEIPEPPSPEDLEVIEDVLTEKQPPPTKRRKPLLPAAPEAMREMTPEMNTFEDNSAEPETPPVQEPEGPPEVDDAMRAPSKPRRAPSVTVRDTYQEATVEKKTLRISRKKPELPPDEVPEAPREVVAKKKVPPPQVPEVVPVKAPGTPKEVVSERKLLEEPSKKPAVLPVPVPEEPKEVIPEKKVSLVPAKKPAAPPTTVPEAHEEDFPEEEVPLVLPQEPEAPPAKVPEPPKEVVPEKKVSMVPPKRPEAPPAKVPEAPKEVVPEKKVSVAPKKKPEAPAVKVPEAPKKVVPEKKVPVAAPKKPEAPAAEVPEVPKAAVPQKKIPEAVPPKPESPPPEAPEVPPKEVTPEKKVPVVPPKKPEAPPPKVPETPQEAVSEEKTPKALPKKAEAAPVPVPEVQETVPEKTRPAAPPKKPEATPMPVPKVQEIVPEKTRLMAPSKKPEATTVPVPEVQEIVPEKTRPVAPPKKPEATTVPVPEDQETVPEKTRPVAPPKKPEVTPVPVPKVQEIVPEKTRPAASPKKPEATPVPVPEIQGTVPEKTRTVGPPKKPEAIPVSVPEVQEPIPEKTRPAAPPKKPEVTTVPVPEEPKEVIPEKKVSLVPAKKPAAPPTTVPEAHEEDFPEEEVPLVPPQEPEAPPAKVPEPPKEVVPEKKVSMVPPKRPEAPPAKVPEASKEVVPEKKVSVAPKKKPEAPAVKVPEAPKKVVPEKKVPVAAPKKPEAPAAEVPEVPKAAVPQKKIPEAVPPKPESPPPEVYEEPAEEIVPEEPPEEVVEEPEPAPPPKVTVPPKKPVPEKKAPPAVVKKPEPPPAKAPEVPKEAPPEKKVPSVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVVEEKPVIEEKPAIPVAEKVESPPTEVYEEPEEVAAQE------EEPAPVVEEEEYEAPPPPAPVPEEPKKVVPEKKYPVIKKPEPPPPKVPEVSKKPAPMKKVPVVKKPEPPEAEVPEVPKKLAPVKKEPVPVTKKPEVLPEKVPEAPKKITPEKRESAPVPEEPEAPPAPVEEIPEETIYEEKATITIGRKETPPVEEREIERFIQPEEPGMEPQPEETPVQEPEPEKKVIEKPKLKPRPPIRAPSPPKEDVKEKIFQLKAVSKKKVPEKPEVVEKVEPTPLKEPPPPPKAVEVEAPPEPKPKERKVPEPTKVPEIKPAIPLPGPEPKPKPEPEVKTMKAPPIEPAPTPIAAPVTAPVVGKKAEAK-PKDEAAKPKGPIKGVAKKTPSPIEAERKKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEIIREWLVKPIRDQHVKPKGTAVFTCHIAKDTPNIKWFKGYDEIPLEPNDKTEILKEGNHLILKVKNAMPEDIDEYAVEIEGKRYPAKLTLGERDVELLKPIEDVTIYEKESASFDAEISEEDIPGEWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQACNAVTTAILTVKEIELDFAVPLKDVTVPEKRQARFECVLTREANVIWSKGPDIIKASDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSAQLFVTGIRLKFISPLEDQTVKEGQ---TATFVCELSHEKMHVVWFKNDVKLHTTRTVLMSSEGKTYKLEIRETTLDDISQIKAQVKNLSSTANLKVLEADPYFTVKLHDKTGVEKDEIILKCEVSKDVPVKWFKDGEEIVPSPKHSVKTDGLRRILKIKKAELKDKGEYTCDCGTDTTKANVTVEARLIKVEKPLYGVEVFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHVLVLYNCQLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEIAGDDRFELIKDGTR--HSLVIKSAAFEDEAKYMFEAEDKRTSGKLIIEGIRLKFLTPLKDVTAKERENAVFTVELSHDNIPVSWFKNDQRLHTSKRVSMHDEGKTHSITFKDLSIDDTSQIRVEAMGISSEAKLTVLEGDPYFTGKLQDYTGVEKDE---VVLQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDQTSGKLDIEDREIKLVRPLYSVEVMETET---ARFETEISEDDIHANWKLKGEALLQTPECEIKEEGKIHVLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPNDKVVTRSEGRVHTLTLRDVKLEDAGEVQLTAKDFKTQANLFVKEPPVEFTKPLEDQTVEEEATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLIIHGCTPEDIKTYTCDAKDFKTSCNLNVIPPHVEFLRPLTDLQVKEKETARFECEISKENVKVQWFKDGAEIKKGKKYDIISKGAVRILVINKCLLNDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANLEVSEGDTIKLVCEVSKPGAEVTWYKGDEEVIETGRFEILTDGRKRILIIQNAQLEDAGSYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCTISKESFEVQWKRDDQTLESGDKYDIIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTKVKEQQEAVFNCEVNTEGAKAKWFRNDEAIFDSSKYIILQKDLVYTLRIRDARLDDQANFSVSLTNHRGENVKSAANLIVEEEDLRIIEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVAFDNRISYRIDKYKHSLIIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDD---AVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLEDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVIFLAELNKDKVEVQWLRNNMIVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAPPKIKTSDQDLVVDAGQPLTMVVPYDAYPKAEAEWFKENEPLSTKTVDTTAEQTSFRILEAKKEDKGRYKIVLQNKHGKAEGFINLQVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLVTDRADSCEFTVTGLQKGG--VEYLFRVSARNRVGTGEPVETDSPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLSASEQTQSSVQLTWEPPLKDGGSPILGYIIERQEEGKDNWIRCNMKPVPELTYKVTGLQKGNKYLYRVSAENAAGVSDPSEILGPLTADDASVEPTMDLSAFKDGLEVIVPNPIKILVPSTGYPRPKATWTFGDQVLEAGDRVKIKTISAYAELIISPSERPDKGIYTLTLENPVKSISGEIDVNVIARPSAPKELKFSDVTKDSVHLTWEPPDDDGGSPLTGYVVEKRDMSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYTDEPVNMSAPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVEKCPRGSDKWVACGEPVPDTKMEVTGLEEGKWYAYRVKALNRQGASKPSKPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADTLLRPD-QRITIENVPKKSTVTITDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERKATDSDVWHKLSSTVKDTNFKATKLTPNKEYIFRVAAENMYGVGEPVQATPIIAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSRSTEPILIKDPIDPPWPPGKPTVKDIGKTSLVLNWTKPEHDGGAKIESYVIEMLKTGTDDWVRVAEG-VPTTEHLLTGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIGDSVLAKDTFTTPGPPYALTVVDVTKRHVDLKWEPPKNDGGRPIQRYIIEKKEKLGTRWVKAGKTSGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPVGPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAVGVSDPSEISENVVAKDPDCKPTIDLETHDIVVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVHADAGVYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGSPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKIGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAKAMTITWKPPLYDGGSKIMGYIIEKLAKGEDRWKRCNEHLVPVLTYTAKGLEEGKEYQFRVRAENAAGIGEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDATISGSPYPTITWIKDENVIVPEEIKKRVAPPVRRKKGEAEEEEPFTLPLTERLSINNSKQGESQLRVRDSLRPDHGQYMIKVENDHGVAKAPCTVSVLDTPGPPINFVFEDIRKDSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVITSTLRNCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLLAKDPFEPPDAPDKPIVDDVTSNSMVVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKALLSSLKTKVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTARDPISPPGPPVPRVADTSSTTIELEWEPPAFNGGGEIMGYFVDKQLVGTNEWSRCTEKMVKVRQFTVKEIREGADYKLRVSAVNAAGEGPPGETEPVTVAEPQEPPTVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTIEEGE--LDKERVVIENVGTKSELIIKNALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPADDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLIEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSDGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVDNLDEHQMYEFRVKAVNDIGESEPSLPLNVVIQDDEVPPTIKLRLAVRGDTIKVKAGEPVNIPADVTGLPMPKIEWSKNEKVIEKPTDALNITKEEVSRSEAKTELSIPKAVREDKGTYTITASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYIIDKRDASRKKSEWEEVTNTAVERRYGIWKLIPNGQYEFRVRAVNKYGTSDECKSDKVVIQDPYRLPGPPGKPKVLERTKGSMLVSWTPPLDNGGSPITGYWLEKREEGGAYWSRVSRAPITKVGLKGVEFSVPRLIEGVKYQFRAMAINAAGIGPPSEP-SDPAVAGDPIYPPGPPSCPEVKDKTKSSISLAWKPPAKDGGSPIKGYIVEMQEEGTTDWKKVNEPDKLLTACECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEVPEVFIDIGAQDCLICKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGIHDIPEDAQLETAENSSVIVIPECTRAHSGKYSITAKNKAGQKTANCRVKVMDAPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKKTIDGKAWTKVNPNCGSTAFVVPDLISEQQYFFRVRAENRFGIGPPAETIQRTTARDPIYPPDLPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGKKKEAWRQCNRRDVEELEFTVEDLVEGGEYEFRVKAVNEAGVSKPSATVGPVTVKDQTCPPSIELKEFMEVEEGTDVNIVAKIKGVPFPTLTWFKAPPKKPDSKEPVVYDTHVNKQVVDDTCTLVIPQSRRSDTGLYSITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESISADQMTLSWLPPKDDGGSKITNYVIEKREANRKTWVRVSSEPKECMYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPVTARDPVAPPGPPFPKVTDWTKSSVDLEWSPPLKDGGSKITGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGVGEPGEVTDIIEMKDRIVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERALPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEGGERKKTIIVDVLDVPGPVGIPFLSDNLTNDSCKLTWFSPEDDGGSPITNYVIQKREADRRAWTPVTYTVTRQNATVQGLIQGKSYFFRIAAENSIGMGPFVETPNALVIRDPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLDLDFRDKLTVRVGEAFALTGRYSGKPKPKVDWFKDEADVLEDDRTHIKTTPTTLALEKTKAKRSDSGRYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVVFDEVTKEYMVISWKPPLDDGGSEITNYIIEKKELGKDIWMPVTSASAKTTCKVPKLLEGKDYIFRIHAENLYGISDPLVSDSMKARDRFRVPDAPEQPVVTEVTKDSALVTWNKPNDGGKPITNYILEKRETMSKRWVRVTKEPIHPYTKYRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFARDPIAKPSPPINPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNEAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDREAPTKAQIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVVTNYVVERKDVATAQWSPLSTTSKKKSHMAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGAKDWIKFKTVKNLECVVTGLQQGKTYRFRVKAENIIGLGLPDTTIPIECQEKLEPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWATDGTEITTDDHYTVETDSFSSVLTIKNCLRKDTGEYQLTVSNAAGTKTVAVHLTVLDVPGPPTGPINILDVTPEYMTISWQPPKDDGGSPVINYIVEKQDTRKGTWGVVSAGSSKLKLKVPHLQKGCEYVFRVKAENKMGVGPPLDSIPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYVERREITGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSNPSPSSDPIKACRPIKPPGPPINPKLKDKTKESADLVWTKPLSDGGSPILGYVVECQKPGTTQWDRINKDELIRQCAFRVPGLIEGNEYRFRIRAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWSKEGKVLVKDKRVDLIHDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVSNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSADWERVHKGSIKETHYMVDKCVENQIYEFRVQTKNEGGESDWVRTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTSAESSKFSLTKAKRSDGGKYVVTATNPAGSFVAYATVNVLDKPGPVRNLKIADVSSDRCTIRWDPPEDDGGCEIQNYILEKCESKRMVWSTYSANVLTPGATVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDRPGRPDPPEVTKVSKEEMTVVWNAPEYDGGKSITGYYLEKKEKHAVRWVPVNKSAIPERRLKVQNLLPGHEYQFRVKAENEVGIGEPSLPSRPVVAKDPIEPPGPPTNFKVVDTTKNSITLAWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRMEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIRPKEILEPPEIDLDASMRKLVVVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVKVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSPVTHYIVEKREAERKTWSTVTPEVKKTSFNVTNLVPGNEYFFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKVEVTEMTKNSATLAWLPPLRDGGAKIDGYIISYREEDQPADRWTEYSVVKDLSLIITGLKEGKKYKFRVAARNAVGVSMPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRVEAHVYGKPNPICKWKKGEDDVVTSSHLAIHKADSSSVLIIKDVTRKDSGYYSLTAENSSGTDTQKIKVTVMDAPGPPQPPFDISEIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMLAKFPFDVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPITGYLIERKERNSLLWVKANDTIVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVVDVTKNSASLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTTPHQIPLEEYTATGLEENAQYQFRAIAKTAVNISQPSEPSDPVTILAENVPPRIELSVEMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDSTPIKQTEGVKMAMKRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYADRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCTVEKLIEGHEYQFRICAENKYGVGDPIFTEPVIAKNPYDPPGRCDPPVISNITKDHMTVSWKAPADDGGSPITGYLVEKRETQAVNWTKVNRKPVIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAVYAQDPLYPPGPPAFPKVYDTTRSSVSLSWGKPAFDGGSPIIGYLVEVKRADSDHWVRCNLPEKLQKTRFEVTGLMENTEYQFRVYAVNKIGYSDPSDVPDKHCPKDILIPPEGELDAELRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRERIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYITWDPPIIDGGSPIINYVVEKRDAERKSWSTVTTECPKTSFRVSNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASETPGPVVDLKVLAVTKSSCTIGWKKPRSDGGSRITGYVVDFLTEENKWQRVMKSLSLQYSTKDLKEGKEYTFRVSAENENGEGTPSEIMVVAKDDVVAPDLDLKDLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESTAVNTTLVVYDCQKSDAGKYTITLKNVAGTKEGTLSIKVVGKPGIPTGPIKFDEVTAEAMTLKWGPPKDDGGSEITNYVLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYTFRVSAENKYGVGEGLKSEPIVAKHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHIEFKERNSLLWKRANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVISVTRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPDCAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTGTIICKDEYEAPTIVLDPTIKDGLTVKAGDSIVLSAISILGKPLPKSSWSKAGKDIRPSDIAQITSTPTSSMLTVKYATRKDAGEYTITATNPFGTKEEHVKVSVLDVPGPPGPIEISNVSAEKATLTWTPPLEDGGSPIKAYVLEKRETSRLLWTVVSEDIQACRHVVTKLIQGNEYLFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPGKPEISNVTKNTATVSWKRPIDDGGSEITGYHVERREKKGLRWVRATKTPVSDLRCKVTGLQEGNTYEFRVSAENRAG--IGPPSDASNPVLMKDVAYPPGPPSNAHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDDAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAVNDAGVGEPAVIPNVEIVEKETAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKH--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTVTTKCHKCTYKVTGLTEGCEYFFRVMAENEYGIGEPTETTEPVRASEAPLPPDSLNIMDITKNTVSLAWPKPRHDGGSKITGYVIEAQRKGSDQWTHISTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIARAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNVENTATSTILNINECVRSDSGAYPLTAKNTVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWEPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGVEYQFRVKAQNRYGVGPGITSASVVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHIERKERNGILWQTVSKALVPGNIFKSTGLTDGIAYEFRVIAENMAGKSKPSKPSEPTFALDPIDPPGKPVPLNITRHTVALKWAKPEYTGGFKITSYVVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDLEAPRIMVDVKFKDTITLKAGEAFKLEADVSGRPPPTMEWAKDGKELEG-TGKLEIKIADFSTHLINKDSSRTDSGAYILTATNPGGFAKHIFNVKVLDRPGPPEGPLAVSDVTSEKCVLSWLPPLDDGGAKIDHYIVQKRETSRLAWTNVATEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE-PVLAVDPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWVKCNKKALTDLRFKVSGLTEGHEYEFRIMAENAAGVSAPSATSPFYKACDSVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQVVTPPAGLKATSYTITNLIENQEYKIRIYAMNSEGLGEPALVPGTPKAEERMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWAREHGESLDKASIESTSSYTLLVVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQNLKIKEVTKTSVTLTWEPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKIDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQSKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKIDVPFIGRPTPTVTWHKDDVPLKQTTRVNAESTENNSLLTIKEACREDVGHYTVKLTNSAGEATETLNVIVLDKPGPPTGPVKMDEVTADSVTLSWEPPKYDGGSSINNYIVEKRDTSTTAWQIVSATVARTTIKASRLKTGCEYQFRIAAENRYGKSTYLNSE-PVIAQYPFKVPGPPGTPFVTLASKDSMEVQWHEPVSDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGIEYEFRVSAENIVGIGKPSKPSECYAAHDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYVVEKKELPDGRWMKASFTNIIDTQFEVTGLIEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVEPPRISMDPKYKDTVVVQAGESFKIDADIYGKPIPTTQWVKGDQELSSTARLEIKTTDFATSLSVKDAVRVDSGNYILKAKNVAGEKSVTVNVKVLDRPGPPEGPVAISGVTAEKCMLAWKPPLQDGGSDIINYIVERRETSRLVWTLVDANVQTLSCKVTKLLEGNEYIFRIMAVNKYGVGEPLESEPLIAKNPFVVPDAPKAPEVTAVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLLENHNYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVMDVTRSSVFLSWTKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNLEVEKLLEKHEYNFRICAINKAGVGEHADVPGPVMVEEKLEAPDIDLDLELRKVINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPARTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKNTDKWSECARVKSLEAVITSLTQGEEYLFRVIAVNEKGRSDPRSLAVPITAKDLVIEPDVRPAFSSYSVQVGQDLKIEVPISGRPKPSISWTKDGAPLKQTTRINVIDSLDLTTLSIKETHKDDGGHYGITVANVVGQKTAAIEIITLDKPDPPKGPVKFDEVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESEPIVAQYPYKEPGPPGTPFVTAVSKDSMVVQWHEPINNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKALNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEAIIVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPEGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCTLAWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYIFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNVHIVDTTKNSITLAWGKPIYDGGSDILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLIEHQEYKIRVCALNKVGLGEAASVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSKEEGEFTDKVQIEKGINFTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSVLLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPAETSDAVKASEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRILGYVVEMQPKGTEKWSVVAESKVCSAVVSGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIEIPVIGRPRPKISWVKDGEPLRQTTRVNVEETATSTILHIKESSKDDFGKYSVTATNNAGTATENLSVIVLEKPGPPVGPVKFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTNWQMVSATVARTTIKVSKLKTGTEYQFRIFAENRYGKSTPLDSKPVVVQYPFKEPGPPGTPFVTSVSKDQMLVQWHEPVNDGGSKVIGYHLEQKEKNSILWVKLNKIPIQDTKFKTTGLDEGLEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIITRNSVTLKWKKPTYDGGSKITGYIVEKKDLPDGRWMKASFTNVVETEFTVTGLVEDQRYEFRVIARNAADNFSEPSESSGAITARDEIDAPNASLDPKYRDVIIVRAGETFVLEADIRGKPIPDIVWSKDGNELEETAARMEIKSTLQKTTLTVKDCIRTDGGQYTLKLSNVGGTKTIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGASISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGVGEPLESEPVIACNPYKLPGPPSTPEASAITKDSMVLTWTRPVDDGGAEIEGYILEKRDKEGIRWTKCNKKTLTDLRFRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWNKPIYDGGAPVRGYVIELKEAAADEWTTCTPPSGLQGKQFTVTKLKENTEYNFRICAFNTEGVGEPATIPGSVVAQERMEAPEIELDADLRKVVTLRASATLRLFVTIKGRPEPEVKWEKAEGILTERAQIEVTSSYTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTVREVKKDSVTLSWEPPLIDGGAKVTNYIVEKRETTRKAYATITNNCTKTTFKIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVVAKDIEIKPSVELPFNTFNVKANDQLKIDIPFKGRPQATVAWKKDGQVLRETTRVNVSSSKIVTTLSIKEASREDVGTYELCVSNTAGSITVPITVIVLDRPGPPGPIRIDEVSCDNVSISWTPPEYDGGCQISNYIVEKRETTSTTWQVVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMVVSWQVPVNDGGSQVIGYHLEYKERSSILWSKANKVLIADTQMKVSGLDEGLLYEYRVYAENIAGIGKCSKACEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPRYDGGAKITGYIVERRELPDGRWLKCNFTNVQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPITVKDDVEAPRIMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGVEIEERAKTEIVSTDS--NTTLTVKDCVRRDTGQYVLTLKNVAGTRTMAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSRLAWTICEAELRTTSCKVTKLLKGNEYIFRVTGVNKYGVGEP---LESV-AVKALDPFTTPSPPTSLEITSVTKDSMTLCWSRPETDGGSDISGYIIERREKNSLRWMRVNKKPVYDLRVKSTGLREGCEYEYRVFAENAAGLSLPSDTSPLVRAEDPVFLPSPPSKPKIVDSGKTTITIGWVKPLFDGGAPITGYTVEYKKSEETDWKVAIQSFRGTEYTMSGLTTGAEYVFRVRSLNKVGASDPSDITDPQVAKEREEEPAFDVDSEMRKTLTVKAGSSFTMTVPFRGRPIPNVSWSKPDTDLRTRAYIDSTDSRTSLTIENANRNDSGKYTLTIQNVLSAASMTFVVKVLDSPGPPANITVREVTKETAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCSRLSYKVTNLQEGAVYYFRVSGENEFGVGVPAETKEGVKITEKPSPPEKLGVTSVSKDSVSLSWLKPEHDGGSRILHYVVEALEKGQKNWVKCAVVKTTHHVVSGLREGHEYFFRVFAENQAGLSDPRELLLPVLIKDHLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGKYEITAANSSGTTKTFINIIVLDRPGPPTGPVAISDITEESVTLKWEPPKYDGGSHVTNYIVLKRETSTAVWTEVSATVARTMIKVMKLTTGEEYQFRIKAENRFGISDHIDSACVVVKLPYTTPGPPSTPWVSNVTRESITVGWHEPVSNGGSAVIGYHLEMKDRNSILWQKANKMIIRTTHFKVTTISAGLIYEFRVYAENAAGIGKPSHSSEPVLAIDACEPPRNVRITDISKNSVNLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVIETQFTVSGLTQNSQYEFRVFARNAVGSVSNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPEPTIEWYKDDKELQTNALVCVENSTDLASILIKDANRLNSGSYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVAENLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESEPVVAKNSFVTPGPPSIPEVTKITKNSMTVVWNRPTVDGGSEINGYFLEKRDKKSLAWLKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGMGPFSEPSDFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSDVTGYVVEMRQGEEEEWTIVSTKGEARTTEYVVSNLKPGVNYYFQVSAVNCAGQGEPITMTEPVQAKDILEEPEIDLDVALRTSVIAKAGEDVQLLIPFKGRPPPTVTWRKDEKNLGSDARYSIQNTDSSSLLVIPQVTRNDTGKYILTIENGVGQPKSSTVSVKVLDTPAACQKLQVKHVSLGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSIVSHKCSGTSFKVMDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVVLSWTKPDFDGGSIITDYLVERKGKGEQAWSHAGISKTCEIEIGQLKEQSVLEFRVSARNEKGQSDPVTIGPLTVKELVITPEVDLSEIPGAQISVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEYVRFSKTEN-KITLSIKNVKKENGGKYTVILDNAVCRNSFPITIITLGPPSKPKGPIRFDEIKADSAIMSWDIPEDDGGGEITCYSIEKREASQTNWKMVCSSVARTTFKVSNLVKDSEYQFRVRAENRYGVSEPLVSNV-IVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQRVNTSPISGREYRATGLIEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVAYSIEKRQGSDRWVRCNFTDVSECQYTVSGLSPGDRYEFRIIARNAVGTISPPSQSSGLIMTRDENVPPTVEFGPEYFDGLVIKSGDSLRIKALVQGRPVPRVTWFKDGVEIERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVSGSTKAEITVKVQDTPGKVVGPIRFTNITGEKMTLWWEAPLNDGCAPVTHYIIEKRETSRLAWALIEDHCEAQSYTAIKLITGNEYQFRVSAVNKFGVGRPLESDPVVAQIQYTIPDAPGIPEPSNVTGNSITLTWTRPESDGGNEIQHYILERREKKSTRWVKVISKRPISETRFKVTGLVEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPSAPAVVKVTDTSKTTVSLEWARPVFDGGMEIIGYIIEMCKADLGDWHKVNTEPCVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLSAPELDIDANFKQTHIVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSIRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGRKSITFTVKVLDSPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVIEKREASRRSWQVVSEKCTRQILKVSDLTEGVPYYFRVSAENEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPEHDGGSRITSYLLEMRQKGSDFWVEAGHTKQLTFTVERLVENTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSTFTIDVPISGRPAPKVTWKLEEMRLKETDRMSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFTITVVVIGRPGP---VTGPIEVSSVSAESCVLSWSEPKDDGGTEITNYIVEKRESGTTAWQLINSSVKRTQIKVTHLTKYKEYCFRVSSENRFGV----SKPLESVPIVAEHPFVPPSAPTRPEVYYVSANAMSIRWEEPYHDGGSKIVGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDPPGRPEVTDVTRSTVSLVWSAPMYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGIISKGSESTGPVTCRDEYAPPKAELDARLQGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKYCDRSDSGKYTLTVKNASGTKSVSVMVKVLDSPGPCGKLTVSRVTEEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEAECLTLSYVVTRLIKNNEYTFRVRAVNKYGLGVPIESEPIVARNSFTIPSQPGIPEGVGAGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNSAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKSSISLAWTKPMYDGGTDIIGYVLEMQEKDTDQWCRVHTNTTIRNNEFTVPDLKMGQKYSFRVAAVNAKGMSDYSETTAEIEPVERLEIPDLELADDLKKTVIIRAGASLRLMVSVSGRPSPVITWSKKGIDLANRAIIDNTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVNVKEVSRDSVTITWEIPTIDGGAPVNNYIIEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPTKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLDHTVISLNEGEQYLFRVRAQNEKGVSEPREIVTPVTVQDLRVLPTIDLSTMPQKTIHVPAGRPIELVIPITGRPPPTASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYMLELKNVTGTTSETIKVVILDKPGPPIGPIKIDEVDATSVTISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRPTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSISIPGPPETLQIFDISRDGMTLTWYPPEDDGGSQVTGYIIERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAINARGTGKPSRPSKPTVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQREWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGVFVRQGGVIRLTIPIKGKPFPICKWTKEGQDVSKRAMIATSETHTELVIKEADRNDSGTYDLVLENKCGKKTVYIKVKVIGSPNTPEGPLEYDDIQTRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVIPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVILQWE-----KPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDRQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSVKTKLTSG--EAPGVRKEMADVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELVQSR-KYKMSSDGRTHTLTVMTEEQEDEGVYTCVATNEVGEVETSSKLLLQAAPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWYHGQKLLQNSESITIENTEHYTHLVMKNVQ--RKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSVVISWKAPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISEPLEVASVVIIKSPFEKPSVPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWIAVTTEEIRETVFSVQNLIEGLEYEFRVKCENLGGESEWSETSEPVTPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRVQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKVTNYIVEKCATTAERWLRVGQARETRYTVVNLFGKTSYQFRVIAENKFGLSKPSEPSEPTVTKEDKTR-----------------------AMNYDEEVDETREVTMTKASHSKTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTFMAKFVKVKG-TDQVLVKKEISILNIARHRNILYLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREVVSYVRQVCEALEFLHSQNIGHFDIRPENIIYQTRKNSIIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSSATDMWSLGTLVYVLLSGINPFLAETNQQMIENIMNAEYTFDEEAFQEISLEAMDFIDRLLVKERKSRMTASEALKHPWLKQRMDRVSTKVIRTLRHRRYYHTLIKKDLNMVVSAARISCGGAIRSQRGVSVAKVKVASIEIGPVSGQIMHAIGEEGGYVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRR-TKKVKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPRVTWYKSGQKIKPGDDDKKYTFESDKGLYQLTINSVTTDDDAEYAVVARNKHGEDSCKAKLTVTLHPPPTETTLRPMFKRLLANAECHEGQSVCFEIRVSGIPAPTLKWEKDGQPLSLGPHIEIVHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVDRLRYVKQEFQTKEERERHVQKQIDKTLRMAEILSGTETVPLTPVAQEALREAAILYKPAVSTKTVKGEYRLETEEKKEERKLRMPYEVPEPRRFKQATVEEDQRIKQFVPMSDMKWYKKIRDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRITDQYRPKWRIPKLTQDDLEMVRPARRRTPSPDYDLYYYRRRRRSLGDISDEELLLPIDDYLAMKRTEEERLRLEEELELGFSASPPSRSPPRFELSSLRYSSPPAHVKVEDRRRDFRYSTYHIPTREETSTSYAELRERHAQASYRQPKLRQRIMAEKEEEELLRPVTTTQRLSEYKSELDYMSKEEKSKKKSKRQRQVTEITEIEEEYEISRRAQRESSSSVSRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRS-HRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCQTEDSGTYRAVCTNYKGEASDYATLDVTGGHYTTYASQRRDEEVPKSVFPELTKTEAYAISSFKRTSEMEAASSVREVKSQMTETRESLSSYEHHVSAEMKSAASEEKSLEEKATVRKIKTTLAARILTKPRSITVHEGESARFSCDTDGEPVPTVTWLRGGQVVSTSARHQVTTAKYKSTFEISSVQASDEGNYSVVVENTDGKQEAQFTLTVQKAKAVEKAVTSPPRVKSPEPRVKSPETVKSPKRVKSPELVASHPKAVSPTETKPT--EKGQQLPVPAPPKITQSLKAEASRDIAKLTCAVESSALCAKEVAWYKDGKKLKENGHFQFHYSADGTYELKIHNLSESDCGEYVCEVSGEGGTSKTSFQFTGQSFKSIHEQVSSTTETKKSVQKTAESAEAKKATQKTAESAEAKKATQKTAESAEAKKPAQKTAESAEAKKPAQKTAEPTEAKKQEPIAPESVSSKPVIVTGLRDTTVSSDSVAKFVIKVTGEPQPTVTWTKDGKAIAQSSKYKLSNDKE-EFILEILKTETSDGGLYSCTVANSAGSVSSSCKLTIKAVKDTEAQKVSTQKTSEVTAKKKESVQQEISQKVLTSEEIKMSEVKSHETLAIKEEASKVLIAEEVKKSAAASLEKSIVHEEVTKTSQASEEVKTHAEIKALSTQMNITSGQRVTLKANIAGATDVKWVLNGTELSNSEEYRYGVSGSDQTLTIKQASHRDEGILTCIGK--TSQGVVKCQFDLTLSKELSDAPSFISQPRSQNINEGQNVLFSCEISGEPSPEIEWFKNNLPISISSNISVSRSRNMYTLEIRNASVSDSGKYTVKAKNFRGQCSATASLTVLPLVEEPPREVVLKTSG---DMSLQGSFSSQSVQMSASKQEASFSSFSSGSAS-MTEMKFASMSAQSMSSVQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGGRGIPPKIEALPSDISIAEGKVLTVACAFTGEPTPEITWSCGGRRIQSQEQQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNINIRSM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D1YSG0-1", "uniprot_id": "D1YSG0_DROME", "id": "D1YSG0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVAEDFAPSFVKKPQLHQED-DGNRLIFECQLLSSPKPDIEWFRSDNKVVEDVRTKFKIQP----------------------------------------------------------------------------------------VGENKYTVVLELDDVVETDAGLYKVKAKNKSGEVSASINLNFTPADEPKEKQIDG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FAPTFAKKPAIRQEEDGKRLLFECRVNADPIPAIIWFHNGAAVKESERHKITVDK-----------------------------------------------------------------------------------------DVHSYFATLEILNVTVEDAGKYKVNAKNELGESNATISLNFDSDEAPVPESAEG---------------------------------------------------------------------------------IKPTFTERPVIRQSEDGGNVTFECRCVGDPTPTVTWSHGETELNESNRYKMSLT-------------------------------------------------------------------------------------------MDQKLYHIACLEISSVVSSDQGEYRAQAKN----------------------------------------KHGSGVATINLNFESGSKKIPDG-----------------------------------------------KSPRFPKKP---TIRQEEDLLIMECVLEAHPVPDIVWYCSEKEICNNQRTKMTRKAITKDSYILTLEIQNPTKEDGGNYRCNAINMYGESNANIALNFQGASDANGFAPSFIEKPRIIPNESGTLITMKCKCKAKPEPTVTWYRGQDLVEKSKKIKINTTVIAEDTYELTLEIKDP-----------------------------------------------------------------------------------------GATDGGTYRCNVKNEYGESNANLNLNIEAEPEPEGEG-----------------------------------------------------------------------------------------PTFIEKPRIVSENNGKLVIMECKVKADPKPDVIWFRNGEVIKESNK----IKTFIEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGDQYYIKLELLDPQLEDSGLYKCNIKNTLGE-LNANLTLNIEIVPVIKDKPKIIKIIKKRTVVIECTVASKFEPKCTWYKETSTVKESKRHVYQVEQTKEGEFAVKLEIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVEESDKGAYKLVASNEKGEAVSQIVN-------------------------------------------------------------------------------------------LVDIPEEERKPCKPEISRKLADQKVAESKTFELLVSLSQTDRKCKVEWYKGSTVIRETKDITTTFDGTTARLTFSSARTEHTSNYKVIVTNEVGKDESSCKITVEKVAKKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKPKEKEKTKNEKEVEQKEMEEDKNESGQSVAQTEGRINIEQIS----------------------------EGDPKEELTVKEEILDKRDTQEVKESSVELQDSAGHEVPE---------------PKKATSDSKLDQSNQKNLDKKHKTDQSESKTNKNVSLAEPIKSNKQESEEQQATEQIGLKKVDRKASIVSVKEEISS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVRRKSTIKAKEEITVDDK-----------------------------------------------------------------------------------------------------------------------------------KASSRRSSLAVEESNTESRRSSIIDKKP-------------------------------------------------------------------------------------------------LEQVDNKPIDANKNPQPLKEEIPRLKPAEKRRTSKVIEEPKPDEGLPKLRKASIAQVKEEAKPAAPKLKAKAKAKPKYEELPEIPDYE----------------------------------------------------------------------------------------------------------------------------------------------RPQLEKYEKSDFTPSDFARDLEIPNKMEKPIIDSGKKEPAVLAQKNGIPK-------------------------------------KTDIIEQYADEPKGLKVGKGKLPDEGDGRDGAVLKPVIIEPEKEILDLGNKKNNQHADKPTVLDIIKQRRRSSIRNLMTKEPIQNESFLGVVLKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VIKDTREQAAPQQAIQLTKANATEQFSPT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KAVKAQVADLKKPETLATLEDNYER------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVLEKYDPFSIDKTKSEKSTPSIITPDIRG-PEVKLPVQETKEEKQKVPKMQPPAPGDPPKIEVIREKRPSLAPEPPSRRGSLIPPAD-----------------------TGRRPSLIINDEKKLRPGE---------------------------------------------------VMDTRLLRPGEVGEGQRRRPSIDVRRPSVQDLEDLINKP---------------STPLRDVGDGGPPSIVDVQESYSVVEDSTAYLTVGVE--------------------------------------------------------------------------------------------GSPAPTFKFYKGVSEILEGGRFKFLTDGQTNTITLCMRKCKPNDESKYKIVVSN------------------------IHGEDSAEMQLYVSD--------------------------------------------------------------------------------------------------------SSGMDFRAMLKKRRYQKWDKDEQDPNWGDLKETEKPLPALKKVERKVESFLSPLIDQFAKEGKD-KKVVFEARFSKPNCKPKWLFRKDEVFTGSKFKFKQENDTYQLIITTPKVEDTGKYTIEIGGVSSTAFLNVEEADPTYTFTKPLKKKLEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTQHETTLECSVSSSMANVHWFKNNTKLESDDPRYLISKDINGNLKLIIKDSVLDDAGLYRCQLDKQPDK---------------------------------------------------------------------------------------TECNLKVTEYPYKFVKVLKSQQCIEKDT---VTLACEIDDAMGEVQWLRNGEEIKPDKRIQIVKDGRKRKLVIKDCKVTDAGQFKCTTNADTTESEIIIN-YQNRFNKKLKDTEAVEREK---LILDIELQDQTAPCDWKFNGEPIVPSESIEIKNMG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKHQLIFSSLDMSNEGEITCESGQLSSKCKLSIRKGESRPNIDCPDKFSGPISA---PVLLEVPFKVSGTKQTPVEAKLFKDGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPVKDVEVAVTDDKVTFKIKKPSRDLSGPYQIKISNGQGEDTKDVQIICQDVPQPPQDVDITDVYQTSCVVSFNPPSDDGGTPITKYVIERQDLSKKHGWESVAEVLPSEPCLKKIDDLIPKKQYRFRIRAVNAIGQSDPATFKNTILAKDPWDEPGKPKAVDLTDWDKDHADLKWEAPETDGGDPITAYIVEYKEKFSNDWVSGKEVDGDARTATVDGLKEGQQYEFRVRAVNRAGPGEPSDKTKSIIAKCRFVKP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FIVGEGLKNVTVKKGQTIRFDIKYDGEPEPAATWVKGTDNLKFDNQRICLDQLERNSSITIKKSVRKDTGKYKLVLSNSSGTIESEAQVVVLDRPLP--------------------------------------------------------------------------------------------------PGGPFEPEEIRASHIKMKWKRPDDDGGCEISGYALERMDEETGRWIPAGEVGPNETSFDFKGLTPNKKYKFRVKAINKEGESEPLETFDAIVARNPYDPPSPPSQPVIDDYDNKSVLLKWKRPPSDGGRPITHYIVEIKDKFAPSWSEVAKTDDPNPECNVEGLKEKMVYQFRVRAVNKAGPSEPSQPTDNHLCKHKNLKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIDRSTFKRVTIKSGRTHKWSVDVLGEPIPELHWSWRDDIPLTNGDRIKIENVDYHTDFSITNVLRKDSGFYTLKAENRNGIDRETVELVVLGKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSPKGPLAVSDVTASGCKLQWKKPEDDGGVPIKEYVVEKMDTATG-----------------------------------------------------------------------------------------------------KWVRVGRSPGEKE---PPSFDVTGLSLGSEYMFRVSAVNEEGESEPLTT-LVGVVAKDPFDEPNKPGTPEVTDYDNQSISLKWAAPNNDGGAPIQKYIIEKKNKNKTEWEKALEIP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDQLEATVAGLQEYGEYQFRVIAVNKAGLSPPSDASVPQIVKYKKLKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIDRSNLKPLLIRAGKPIRYDVNVRGEPAPVITWYQNDKELKPEELPSSSEIKN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IPYNTKISIIETVRKHTGIYKIIAVNEHGQDEATVEVNILAPPSKPRGPLDVKDVTKDSCKLKWKKPEDDGGKPISAYQVEKFDKKQ--------------------------------------------------------------------------------------------------GRWVPLGRTSANDTEFDVKGLQEGHEYQFRVKAINEEGESDPLDSDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIIAKNPYDAASKPGTPNIVDYNEHMVKLKWEAPRSDGGAPISGYIIEKKDKFSPIWDEILSTNTSVPEATVEGLVEGNIYQFRVRAVNKAGFSDPSDATEPHLAKPRNLKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YINRDKMKP--------IKVRAGQPVKFDVDVKGEPAPSLTWFLKETELTSTGQVRLENIDYNTKLTLLDTDRKQSGQYKLRAENINGVDEAVVEVIILDKPSKPEGPIEVSDIHKEGCKLKWRKPKDDGGIPITGYVIEKMDTATGKWVPAGSVDPEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDIEIKGLDPNHRYQFRVKAVNEEGESEPLETESAITAKNPFDVSAPPGLPELEDWDEHHVKLKWEPPIRDGGSPITNYIIEVMDKDSGEFVKA-VETDSPVCKGVVKKLEEGQQYKFRVRAVNKAGPSDPSEQTNWHVAKPRFLKP--HIDRVNLKPVIVKTGLSISLDINIRGEPAPKVEWFFNNSSVTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEHSVKIDNVDYNTKFFVMRAQRSQSGKYIIKATNEVGEDEAELEVTVLGKPGKPKGPLQVNDITKHSCKLKWEKPDDDGGSPIDYYEIEKLDPHTGQWLPCGKSTEP-----------------------------------------------------------------------------------------------------EAKVIGLHEGKAYKFRVRAVNKEGESEDLETEKPIIAKNPYDEPDRP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKPEPTNWDKDFVDLAWDPPKNDGGAPIQKYVIQMRDKSGRAWVDSATVPGDKCNGTVTGVEEGHEYEFRIVAVNKAG--PSDPSDVSKSVIAKPRFLKP-------------------------------------------------------------------------------------------------------HIDRKNLQKKIMRSGQMLHIDALIKAEPPAKVTWTYNKTEIKTSDHIKIENEDYKTTFIMPKVKRADRGIYIVTAKNDSGSDTVEVELEVLCKP------------------------------------------------------------------------------------------------SKPKGPLAVSNVTAETLHLKWEKPEDDGGDPIEQYLVERMDTETGRWVPVLTTKTPEADVTGLTEGKEYLFRVKAVNSEGESEP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVTDIPTKAKNPFDAADTPGKPQIVDWSGNHCDLKWRAPEDDGGASITGYIVERKDPNTGKWQKALETSTPDCKARVNDLIAGNKYQFRIMAVNKAGKSKPSEPSDQMTAKDRFAPP-----------------------------------------------------------------------------------------------------KIDRTNIKDITIKAGQHIRFDIKVSGEPPATKVWLHNKARLENDDSNYNIDMESYRTKLTVPISKRFHSGKYTLKAENESGRDEASFEVIVLDKPGPPEGPLRVTDVHKEGCKLKWNAPLDDGGLPIDHYIIEKMDVESGRWLPSG-RFKESFAELNNLEPSHEYKFRVLAVNTEGESEPLTGEQSVIAKNPFDEPGKPGTPEAVDWDKDHVDLVWRPPINDGGSPITGYVVEKREKGTDKWIKG--------------------------------------------------------------------------------------------------TEITIPCLGEECKATVPTLNENCEYEFRVKAINAAGPGEPSDASKPIITKPRKLAPKIDRKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRTYNFKSGEPIFLDINISGEPAPDVTWNQNNKSVQTTSFSHIENLPYNTKYINNNPERKDTGLYKISAHNFYGQDQVEFQINIITKPGKPEGPLEVSEVHKDGCKLKWKKPKDDGGEPVESYLVEKFDPDTGIWLPVGRSDG-PEYNVDGLVPGHDYKFRVKAVNKEGESEPLETLGSIIAKDPFSVPTKPGVPEPTDWTANKVELAWPEPASDGGSPIQGYIVEVKDKYSPLWEKALETNSPTPTATVQGLIEGNEYQFRVVALNKGGLSEPSDPSKIFTAKPRYLAP-----------------------------------------------------------------------------------------------------KIDRRNLRNITLSSGTALKLDANITGEPAPKVEWKLSNYHLQSGKNVTIETPDYYTKLVIRPTQRSDSGEYLVTATNTSGKDSVLVNVVITDKPSPPNGPLQISDVHKEGCHLKWKRPSDDGGTPIEYFQIDKLEPETGCWIPSCR-----------------------------------------------------------------------------------------------------STEPQVDVTGLSPGNEYKFRVSAVNAEGESQPLVGDESIVARNPFDEPGKPEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKATDWDKDHVDLAWTPPLIDGGSPISCYIIEKQDKYGKWERALDVPADQCKATIPDLVEGQTYKFRVSAVNAAGTGEPSDSTPPIIAKARNKPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIDRSSLVEVRIKAGQSFTFDCKVSGEPAPQTKWLLKKKEVYSKDNVKVTNVDYNTKLKVNSATRSDSGIYTVFAENANGEDSADVKVTVIDKPAPPNGPLKVDEINSESCTLHWNP---------------------------------------------------------------------------------------------------PDDDGGQPIDNYVVEKLDETTGRWIPAGETDGPVTALKVGGLTPGHKYKFRVRAKNRQGTSEP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTTAQAIIAKNPFDVPTKPGTPTIKDFDKEFVDLEWTRPEADGGSPITGYVVEKRDKFSPDWEKCAEISDDITNAHVPDLIEGLKYEFRVRAVNKAGPGSPSDATETHVARPKNTPP-----------------------------------------------------------------------------------------------------KIDRNFMSDIKIKAGNVFEFDVPVTGEPLPSKDWTHEGN-MIINTDRVKISNFDDRTKIRILDAKRSDTGVYTLTARNINGTDRHNVKVTILDAPSVPEGPLRNG---------------------------------------------------------------------------------------------------DVSKNSIVLRWRPPKDDGGSEITHYVVEKMDNEAMRWVPVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DCTDTEIRADNLIENHDYSFRVRAVNKQGQSQPLTTSQPITAKDPYSHP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKPGQPQATDWGKHFVDLEWSTPKRDGGAPISSYIIEKRPK-FGQWERAAVVLGDNCKAHVPELTNGGEYEFRVIAVNRGG-PSDPSDPSSTIICKPRFLAP--FFDKSLLNDITVHAGKRLGWTLPIEASPRPLITWLYNGKEIGSNSRGESGLFQN--ELTFEIVSSLRSDEGRYTLILKNEHGSFDASAHATVLDRPSPPKGPLDITKITRDGCHLTWNVPDDDGGSPILHYIIEKMDLSRSTWSDAG-MSTHIVHDVTRLVHRKEYLFRVKAVNAIGESDP---LEAVNTIIAKNEFDEPDAPGKPIITDWDRDHIDLQWAVPKSDGGAPISEYIIQKKEKGSPYWTNVRHVPSNKNTTTIPELTEGQEYEFRVIAVNQAGQSEPSEPSDMIMAKPRYLPPKIIT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLNEVRIKCGLIFHTDIHFIGEPAPEATWTLNSNPLLSNDRSTITSIGHHSVVHTVNCQRSDSGIYHLLLRNSSGIDEGSFELVVLDRPGPPEGPMEYEEITANSVTISWKPPKDNGGSEISSYVIEKRD----------------------------------------------------------------------------------LTHGGGWVP---------------AVNYVSAKYNHAVVPRLLEGTMYELRVMAENLQGRSDPLTSDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVVAKSQYTVPGAPGKPELTDSDKNHITIKWKQPISNGGSPIIGYDIERRDVNTGRWIKINGQPVPTAEYQDDRVTSNHQYQYRISAVNAAGNGKTSEPSAIFNARPLRE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPRFYFDGLIGKRIKVRAGEPVNLNIPISGAPTPTIEWKRGDLKLEEGKRISYETNSE-RTLFRIDDSNRRDSGKYTVTAANEFGKDTADIEVIVVDKPSPPEGPLSYTETAPDHISLHWYSPKDDGGSDITGYIIEFTEFGVDDWKPVPGTCPNTNFTVKNLVEGKKYVFRIRAENIYGASEALEGKP-VLAKSPFDPPGAPSQPTISAYTPN--------------------------------------------------------------------------------------------------SANLEWHPPDDCGGKPITGYIVERRERGGEWIKCNNYPTPNTSYTVSNLRDGARYEFRVLAVNEAGPGHPSKPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPMTAEHQRYRPDPPEPPKPDRITRNGVTLSWRPPRTDGKSRIKGYYVEMRPKNGK------------------------------------------------------------------------------------------------------DWKTVNDIPINSTVYTVPSLKEGEEYSFRVVAEN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVGRSDPSKPSQPITIEEQPNKPCMELG--KVRDIVCRAGDDFSIHVPYLAFPKPNAFWYSNDNMLDDNNRVHKHLTDDAASVVVKNSKRADSGQYRLQLKNTSGFDTATINVRVLDRPSP---PTR-LRADEFSGDSLTLYWNPPNDDGGSAIQNYIIEKKEARSSTWSKVSSFCTVPFVRIRNLVLNKEYDFRVIAENKYGQ----SDPAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSEPILARHPFDIPNTPGIPHGIDSTEDSITIAWTKPKHDGGSPITGYIIEKRLLSDDKWTKAVHALCP-DLSCKIPNLIENAEYEFRVAAVNAAGQSAYSGSSDLIFCRRPPHAPKIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDLSIRDMTVIAGDEFRITVPYHASPRPTASWSLNGLEVIPGERIKFDSNDYASMYYNKSAKRDETGSYTITLTNNKGSDTASCHVTVVDRPLPPQGPLNAYDITPDTCTLAWKTPLDDGGSPITNYVVEKLDNS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSWVKISSFVRNTHYDVMGLEPHYKYNFRVRAENQYGLSDPLDIIEPIVAKHQFTVPDEPGQP-KVIDWDSGNVTLIWTRPLSDGGSRIQGYQIEYRDILNDSSWNAYDYIIKDTKYQLYNLINGSEYEFRIKAKNAAGLSKPSSPSLRFKLKGKFTVPSPPGAPQVTRVGKNYVDLKWE-----KPLRDGGSRITGYIIERRDIGGAVWVKCNDYNVLDTEYTVMNLIEMGDYEFRVFAVNSAGRSEPSLCTMPIKVCEVLGG-KKPDWITRLQDKVAPFGKDYTLQCAASGKPSPTARWLRNGKEIQMNGGRMTCDSKDGVFRLHISNVQTGDDGDYTCEAMNSLGFVNTSGYLKIGSPPIINR---CPSELKLPEGDNSKIKIFYSGDQPLTVILKKNNEVICDSNDDTHVKVNIFDDYVAIYIRNIVKSDGGPYQIEFTNESGSATGEFYVHITGMPSAPTGPMGISYINKNSCMLNWRPPSYDGGLKVSHYVIERKDVSS-PHWITVSSTCKDTAFNVQGLIENQEYIFRVMAVNENGMGPPLEGLNPIRAKDPIDPPSPPGSPQITEIGGDFVHLEWEKPESDGGAHIQGYWIDKREVGSNTWQRVNATICAANQINCINLIEGRQYEFRIFAQNVAGLSTESSASQAVKIIDPQAASPPLIVKPLRDANCIQNHNAQFTCTINGVPKPTISWYKGAREISNG--ARYHMYSEGDNHFLNINDVFGEDADEYVCRAVNKAGAKSTRATLAIMTAPKLNVPPRFR--DTAYFDKGENVVIKIPFTGFPKPRIHWVRDGENIESGGHYTVEVKERHAVLIIRDGS-HLDSGPYRITAENELGSDTAIIQVQISDRPDPPRFPLIESIGTESLSLSWKAPVWDGCSDITNYYVERREHPLSSWIRVGNTRFTSMAVSGLTPGKEYDFRIFADNVYGRSDASDTSTLIKTKESVKKKPIERKWEIDANGRKLRGKADGPVKDYDSYVFDIYSKFVPQPVEISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGNIFAAKFIPVSHSVEKDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTEAEVINYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKITTGTAEFAAPEIVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTGDHSAMKQEINR-DRYLAYREKLRRKYEDFERFLLPIGRLSEYSSLRKLLMEKYKIHDAVFD-------------------------------------------------------------------------------------------------------------RRQAAPRFVIRP----------------------------------------------------------------------------------------------------------------SSQFCYEGQSVKFYCRCIAIATPTLTWSHNNIELRQSVKFMKRYVGDDYYFIIN-RVKLDDRGEYIIRAENHYGSREEVVFLNVQPLPKEQPRYRTES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPVRRREPLPYTFWQEESE------------------------------------------------------------------TAPSFTFLLRP-RVMQARDTCKLLCCLSGKPVPNVRWYKDGRELS-KYEYAMTHSDGVVTMEIIDCKPSDSGKYSCKATNCHGTDETDCVVIVEGEWVTPEQAQLAHN--------------------------------------------------------------------------------------------FLYSGDRKYIEQPIKPAPLP----------IVTSRQYTSSSVQNTSEPQGDKVNVSNSNSSGISNKKKYASNSLQAPGSPSRSRSATKELILPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDSLMCKPEFTKPLHDLTIHDGEQLILTCYVKGDPEPQISWSKNGKSLSSSDILDLRYKNG-IATLTINEVFPEDEGVITCTATNSVGAVETKCKLTIQPLDKNINKRK-------------------------------------------------------------------------VNAGDNAPKIVSHLESRFVRDGDAVN----LACRIIGAQHFDVVWLHNNKEIKPSKDFQYTNEANIYRLQIAEIFPEDGGTYTCEAFNDIGESFSTCTINVTVPGDETKQPSFVKFPTSVSVLEGEGTTFECEIDSELLNLVWLKDGKPIDETLPRYSFTKDGHRYSFAVAKCNMDDVGQYQAKAVSGKAESICAFSMNVHTAES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A2AAJ9-1", "uniprot_id": "OBSCN_MOUSE", "id": "A2AAJ9-1", "name": "Obscurin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHSFSGAPRFLTRPKAFVVS-VGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGD---------------------------------------------------------------------------------------------VYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHG-------------------------------------------------------------------------------------------ESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEG-------------------------------------------------------------IPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYED-----------------------------------------------------------------------------------------------EQENFVLKILFCKQSDRGLYTCTASN-----------------------------------------------LVGQTYSSVLVVVR-------------------------------------------------EPTVPFKKRLQDLEVREKESATFQCEVA-QPATEAAWFKEETRLWASAKYDIE-----EEGTERRLTVRNVSADDDAVYICETTEGS---RTVAELSVQG---------NLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMG--------------------------------------------------------------------------------------------------EVAFVSGGCRTTTQFCVSAPRRP---------------------------------------------------------------------------------------------PLYPPADPVVKAKTESSVTLSWSAP--PHGDRPVTIDGYVLEKRKLGAYAWSR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LHGAQLKFVANGIETS--------------------------------------------------------------------------------------------------IQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKG------------------------------------VWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKG---------------QQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDVAEPKLVFAKGQQAHSEVK----------------------------------------------------------------------------------------------------------------------------------AEAGASATLSCEVAQAQTEVTWFKDGKK----------------------------------------------------------------------------------------------LSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKD------------------------------------------------------------------------------------------------------------------------------------------------GKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFR------------------------------------------LDVTEPKLVFAKEQQARSEVKAEVG---NSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLSFRLDVAEPKLVFAKEQQARSEVKAEAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSATLSCEVAQAQTEVTWFKDGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTE-----------------------------------------------------------------------------------------------VTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAE----GQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLS-------------------------------------------------------------------------------------------CEVAQAQTEVTWFK--DGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQT-------------------------------------------------------------------------------------EVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCS--RRLVVQQAGKADAGEYSCEAGGQKLS-----------------------------------------------------------------------------------------FRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAG---EYSCEAGGQKLSFRLDVAEAESQIPERPSRREP-----LVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKR---------HEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEPVEGELGGTVMLVCELSPE-QAEVVWRCGNTQLRPG-KRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSG------------------------------------------------------------------------------------------------------LSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASR--SLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEP------QTVEERTSVTLEVELTRPWP-----------------EVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDG-------------------------------------------------------------------------------------------------VELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSS-------AQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAP----------------------------------------------------------------------------------------------KAVQWYKDDTPLSPSEKFKMA--LEGQMAELRILRLTPADAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKD-EDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSAR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVVKGKPVVFLKALDDVSAEERGTLTLQCEVS-DPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVG---ITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLG-------------EDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRAS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKHVPSQEGLTLKLTINALERTDSDTYTCDIG-----------------QARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSN----------------------------------------------------------------------------------------------------ELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVR--------------------------------------------------------------------------------------------------------FRESLKDVEVPEGKAATLRCVLSS-VAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTS-----------------------------------------------------------------------------------------------------------------ATLTVKTSSAQFVGKLRNKEATEG--TTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALP----------------------------------------------------------------------------------------------------AKFKDSLKNEEATEGTTATLSCELSKAAP--VTWKKGPKTLQS-GDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQE----KTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMS-KAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQE---------------------------------------------------------------------------------KTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPR--FIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEG--TMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLR--QDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALP----------------------------------------------------------------------------------------------------PRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCG------QEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDG-----------------------------------------------------------------------------------------------------AMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQN---------------------------------------------------------------------------------------------------------------------LQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELS-REAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAP---------------------------------------------------------------------------------------------------KPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVG-SKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRG--------------------------------------------------------------------------------------------------------LVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQG--TLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVR----------------FTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVP-GPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APETRQAVVGEDICLELEVAAD-GGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSG----------DEVPAQPSLPPEAAQEGDLHLLWEALARK------------------------------------------------------------------------------------------------------------RRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRG-------------------------------------------------------------------------------------------------------------------VEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAEN---------------------------------------------------------------------------------------------------------------SMGVSSTKAELRVELTSTDYDTAADATETSSYFS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQGYLSSREQEG----TESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGE----SLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHY-----------LEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRN-MMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVN---KVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLN-EPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRAR------DQHHREQIVAAVEDTSVEGSAHSAQDGADQQAASVLWRLLGSEALGPSPGDLPNTRQSEPPAFEEAASQIPGAASGTPEVSQPGTHKGLEQETTSSGSQGWTVPIRVEGTAWPGAGTG------------------------------------------QLLLDVHSQVIMETTQRTYVCQAPDTG---VTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSS--ARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRS-KTRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKG-VVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSSSSD--------------------------------------------------------------------------------------------NELAPFARAKSLPPSPVTHSPLLHPRG-------------------------------------------------------------------------------------------FLRPSASLPEETEASMPTADAAVPASPQSAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPVTTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTP---------------------------------PPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGS--------------------------------------------------ETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPP-------------------------------------------------------RKKAGLASFRLSGLKGRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVG------------------------------------------------------------ELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQ-LLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR-----------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .* *:.: . *: :.*:: ..* .: * :. . : . : .: * : :: * * * :* * *. .: :.. :: .* * : * :.***.... :: * :* : : . . : *.: .. :.* *. . * *.:..: * ... . . . * . :.* * * * : : .. : : . *:* .*. * * . *.* : .: . : :.. ** ::.: :* : * . *: .* .: . : : . * ::* : :*.. * *:: : : *..: : .* : . * * * :.: : . : * : : * :: * . : : * : .. . . * :. .. * . :* :.. . . : : . *. :. * *: . : * : : : : : . *: :: :. : .. :: . * . * . . . .. : * : . : . . * . .. .:. * . : . . ::: : : : .: : : : . .*::. . :: .: . . .: .: : . : : :: .. : * . : . . . : . . : : : . . : : ::. . : * :. :. .:. . . : * . .. . . . . : : . . . : : : . .: * .: :. . . . .: :. : :: . . * :. . : . * . : .* . :..:* : . * . . . . : . : . : . : * : :. . . .. . * : :: .. : * . : : .. : * : : * : .. . ..::* . * . * :::. * :* . ::. .: *. . . * .: : * . : : . * * . : :.: ...: ...:: : . *: :: : .. .. .. : :* : * .: . : . : *.* *.. :: :. :: .:.:.*.*: . *:*. :: ... : .. ::::.: * . * : : . .* * * *. : :: : . * **: .* * *:::*:::..... : .* .* *:::.. :* *::.* . : .: : : : : . :: * :. *: : * .*: : : . .:: * .: * ... . .: ** :* . .* : : . : . ..: : . :.: :.... : .: . : : : : * *. . : . : .. : ... . :: . . * . :* . . : : . .. : : * : :.: : . .*. . :. : :.* . * .* : . * * . . . : :* * : : * .: : : :. .* . *: . :*: : . . ::*: ..*: * : .:* : : . . : . .: . ... :: * : ::: . . : . *** :. :. * * . . . .:: :. :* .:.: . :: :: .:* .* . * *. : : . :* .. . * . * * .: : . : : . . * .:. : : . : :. :* * .: * . . * *::: .. : . : . :.: *..:: .: : * : : *:: . : . . * : :. * *:: * :... : : : . : : :: : *: . . : .. : . : : . . .* .. * :.:. ::: : . .*...: . ::. . : * : . * . * : :* . . . :* : **: ::*: . . . : : . . . : . : :. : * . :.:*: * .. :. : :: . * .: .. . *: . :. . : .: .* .* . * :: .:.: . : * : * ::::* *. . . . . :. :. .: :. :. :.*.:. . :. . . : * . * . .: . .* : *. . .: : . :: . * . . . ::. :. *: . * *. . : * .. . .: : .: .. : . : : .*.. : * .: .. . .: : :::::..* . . . : .. . . . ::*.* : * :*. .. . : : : * : : : : . . : . . :* . . * : ... *. .. . . :: : : : .* . .*.. : : : : : * : :.. .. * * .. :* : .:.: ::: . : * * : : : : . .* : : . : * :* * . .* . :* ::: :: . . : . .. :. : : . . . * .. *:. :: . . ::* :: **: : .: * . . . . * :. .:* .* * :. *:. : : . * . .:* * . : : : * . *. * :. . : . . : : . . : : : . : . .: *. . ..: : . : :* * . :* : : : . : :. : : : . . *. : : : :: :. .*: .* . . . : . :: : * . * : : . : .* .:. *: . :.. . : * : * * *.:* . : *: . . ... . . * * ::* : : ... : * * :* . :* :::: . . .: * . : : . . . :* .. * . . :. . .* :: *:*:*: . . ... : :. **. : . : . .: : .: . : .: : .* . .: . : : : : . :. : : . . : : : : : . . :: . . *: : * :: . . . * .: : . . .: : . * :.. * * * . : . : : . : * :. : : *. . .: * . .. : :* .: * . . ..* :. : . :*.: :. :: * * * :: : : .: : .* . . :** .* .:. . . .* . .:* . * ::* : : :: : : . .* * * . :. : : . : : .:.*: : :: : :. . * :. : ::: . . . . :. . .* . :. . :* :.: .:* : .:. : .: . : .. : . . : : . * : . :* :. : : * :. . : : . * : .: : : :.. *: ** .. : : : * .. :* . * . ..: : :. .: .: . . : . : *..* . :.. . : * * * :***. :. * :: :* .: * .. * * *.:** * . ** . * . . :: . : . . * : :: . .. :.. . : . : ... : * * *. :. :*: . .. . * : *. : *. . : . . :. : :: * . . . .. .:::. .: : . . . * :. : .. :. . . : . : . . . : : : . . .: *. :.*: . * :..: * :.. . .: : : . ..*:** . : : ::. . * .:.. . . * . . . .: : . .: .*.: . : .. : .: : *. . * . .: . . .: * .* :. . . : : * : .. : : :: * * . . . . . * .. . . : . . * .. : * :: .. . .:.: . * *: * : * .::: .. :: : . * ***:* :.*: * : : * . . * : :. .. . *.: . :* : : : * .: : : : . . .* .:..: . * .. :.: . . *. :: :. . :.. . ::..::. : :: . .. .:. . .* .. :. . . * . : : *. . .: .:: : :. : . : . : . : * * .:. : . :: : : . .:*. . . . .. . .:: :: . :. :* *:. .: :. : . * :: .: .*: * :: :. . . : * : . : : : . .. . . : . ** : * * : ** *. . .* .. : :. . * : : * :: : * . . :: . . * .: * .: :*: * * * * * * : ** : . : .. . * : . *.* * * * . * ..* . : : .* : *. :: * : :. :: .: : : : :: * . * *: :: * *:. . : : . . . :.. :: : * : :. . *.: :. : . :. *. * : * . . :. :: .. . : * . :. : : : .: : : : .:. .* : :.: : * : . : * * * :.**: . :: . .* : * : .* .** * * * .* * * : *:. . :.::. * : *::* * **.*:* . .. ***: : : :* .*: * : * : ** . :::*:*: *. ::::*: .. :.* *: *::*: *.:..:*.:.* *:**:* **: :*: :** * :: *.: :.*: :**: ::: *. :*:*: *.: *: *: .** .:.: : *: :. : :* :* **: * : . * :: :.* ***: . .. . : : : : . : . : : * . . .. . . .*: : . * : : : . : :: : : :. : * * :: . *. : . . : . . * . . . * .: : ...*.. . . . : . : : . : . .: :. .: * : .:. . . : . . . : . : * * :: .. :. . .:* . *:*:* : ... : * * . .* * :* . *. *:. :. * .. : . . . : . :: . :. : * .. * : : . . :: : . * .: . : * . . : . . : : .. : : . . : . . ", "identical_positions": 571, "similar_positions": 2234, "identity": "1.61%" }, { "cls_id": "homologset.agr.FB:FBgn0005670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RRT9-1", "uniprot_id": "CP4V2_RAT", "id": "A2RRT9-1", "name": "Cytochrome P450 4V2", "aln": "MLWLWLGLSGQKLLLWGAASAVSVAGATVLLNILQMLVSYARKWQQMRPIPSVAR---AYPLVGH-ALFMKPNNTEFFQQIIQYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFMYKFLQPWLGLG---LLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNKLEK---HVNQEAFNCFFPITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFKEGRDHKKGLKSLHTFTNNVIAERVNARKAEQDCIGAGRGPLPSKTKRK-AFLDLLLSVTDEEGNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSH-RPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAGYKISKGTEAVIIPYALHRDPRYFPDPEEFQPERF-FPENSQGRHPYAYVP-FSAGPRNCIGQKFAVMEEKTILACILREFWIESN-QKREELGLAG---DLILRPNNGIWIKLKRRHEDDP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBW0-1", "uniprot_id": "CP4V2_MOUSE", "id": "Q9DBW0-1", "name": "Cytochrome P450 4V2", "aln": "MLWLWLGLSGQKLLLWGAASAVSLAGATILISIFPMLVSYARKWQQMRSIPSVAR---AYPLVGH-ALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLG---LLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEK---HVNQEAFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKCLHTFTNNVIAERVKERKAEEDWTGAGRGPIPSKNKRK-AFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSH-RPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERF-FPENSQGRHPYAYVP-FSAGPRNCIGQKFAVMEEKTILACILRQFWVESN-QKREELGLAG---DLILRPNNGIWIKLKRRHEDDP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWL3-1", "uniprot_id": "CP4V2_HUMAN", "id": "Q6ZWL3-1", "name": "Cytochrome P450 4V2", "aln": "MAGLWLGLVWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVAR---AYPLVGH-ALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLG---LLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEK---HINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRR-AFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSD-RPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERF-FPENAQGRHPYAYVP-FSAGPRNCIGQKFAVMEEKTILSCILRHFWIESN-QKREELGLEG---QLILRPSNGIWIKLKRRNADER---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33269-1", "uniprot_id": "CP4D1_DROME", "id": "P33269-1", "name": "Cytochrome P450 4d1", "aln": "-----------MFLVIGAILAS-----ALFVGLLLYHLKFKRLIDLISYMPGPP----VLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEG---LLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE-RPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIP-FSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIA---ELILRTKEPLMFKVRERVY------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22443-1", "uniprot_id": "CP19A_RAT", "id": "P22443-1", "name": "Aromatase", "aln": "---MFLEMLNPMHYNVTIMVPETVPVSAMPLLLIMGLLLLIRNCESSSSIPGPGYCLGIGPLISHGRFLWMGIG----SACNYYNKMYG--EFMRVWISGEETLIISKSSSMVHVMKHSNYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTVRPFFMKALTGPGLIRMVEVCVESIKQHLDRLGD------VTDNSGYVDVVTLMRHIMLDTSNTLFLGIPLD-ESSIVKKIQGYFNAWQALLIKPNIFFKISWLYRKYERSVKDLKDEIEILVE-KKRQKVSSAEKLEDCMDFATDLIFAERRGD-----------------LTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHTVVGDRD---IRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILNIGRMHR-LEYFPKPNEFTLENF------EKNVPYRYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVKTLQKRCIENMPKNNDLSLHLDEDSPIVEIIFRHIFNTPFLQCLYISL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : :: * : :* **:.* . : : : .:::*:. : : :...: :: . .: : *: :: . *: * :: :: * :::: : . : .: . . : : . : :*: :. : :*. *: : : :.: :: * . :. :.: :: . . . . : *:: ::.: : ::: . ** : :: : :. **.: .*: *.* . :::*: :: ::*:** * * *. * ** : * : **: : : * . *..*: * *.* : ** *. *. ***.* *: :*:: *.:: :*:.: :. . .* * .. : : .: ", "identical_positions": 55, "similar_positions": 153, "identity": "9.96%" }, { "cls_id": "homologset.agr.FB:FBgn0005671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZS8-1", "uniprot_id": "D3ZZS8_RAT", "id": "D3ZZS8-1", "name": "Vacuolar proton pump subunit B", "aln": "-----MATQVDGRPSGFT-SNSCDPGTAREHVQVVTRNYITHPRVTYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDSQKTTCEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPAVMAEDFLDINGQPINPHDRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKS-KAVLDYHEDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQVYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPYENRTVFESLDLGWKLLRIFPKEMLKRIPQSVTDEFYSRQ----------------GAQQDPASDTAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YH6-1", "uniprot_id": "VATB1_MOUSE", "id": "Q91YH6-1", "name": "V-type proton ATPase subunit B, kidney isoform", "aln": "-----MATTVDSRSSGFT-GNSCDPGTAQEHVQAVTRNYITHPRVTYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDSQKTTCEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPAVMAEEFLDINGQPINPHDRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKS-KAVLDYHEDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQVYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFITQGPYENRTVFESLDLGWKLLRIFPKEMLKRIPQSMTDEFYSRQ----------------GAQQDPASDTAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15313-1", "uniprot_id": "VATB1_HUMAN", "id": "P15313-1", "name": "V-type proton ATPase subunit B, kidney isoform", "aln": "-----MAMEIDSRPGGLP-GSSCNLGAAREHMQAVTRNYITHPRVTYRTVCSVNGPLVVLDRVKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKS-KAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSRE----------------GALQDLAPDTAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62814-1", "uniprot_id": "VATB2_MOUSE", "id": "P62814-1", "name": "V-type proton ATPase subunit B, brain isoform", "aln": "MALRAMRGIVNGAAPELPVPTGGPMAGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKS-KDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRD----------------SAKH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62815-1", "uniprot_id": "VATB2_RAT", "id": "P62815-1", "name": "V-type proton ATPase subunit B, brain isoform", "aln": "MALRAMRGIVNGAAPELPVPTGGPMAGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKS-KDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRD----------------SAKH---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21281-1", "uniprot_id": "VATB2_HUMAN", "id": "P21281-1", "name": "V-type proton ATPase subunit B, brain isoform", "aln": "MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKS-KDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRD----------------SAKH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31409-1", "uniprot_id": "VATB_DROME", "id": "P31409-1", "name": "V-type proton ATPase subunit B", "aln": "---------MN------------AQQAQREHVLAVSRDFISQPRLTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKNTLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKSVLDDHTDNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGKDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKRIPASILAEFYPRD----------------SRH----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16140-1", "uniprot_id": "VATB_YEAST", "id": "P16140-1", "name": "V-type proton ATPase subunit B", "aln": "-------------------MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPT-KDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* :.: :**:.*.**..******:*:.***.:: ***:: *.*** *.*****: * :*:*********** ::* ****: ** *********:*:***:***.** ::**::*** *.**** ********.**:*.** ***************:******************: . * * * :**:*********:*******.***:**:: ...**********************:**:**** *:***.*********:*****************:********:************.*************************:******:*******: :***:***********************.******** ******. ***********: :* * **** ***:.** ** **:*:*:*:** .*.****:*****:**. *** * . ", "identical_positions": 352, "similar_positions": 81, "identity": "65.55%" }, { "cls_id": "homologset.agr.FB:FBgn0005674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJ92-1", "uniprot_id": "A0A8I6GJ92_RAT", "id": "A0A8I6GJ92-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKE---NLLRVSESVVFTDTNSILRYLARVAATSGLYGSNLMEHTEIDHWLEFSATKLSSCDVLTSAIKELNHCLSLRTYLVGNSLTLADLCVWATLKGNAACQEHLRQSKTLVHVNRWYGFLEAQQAFRSVGTKWD---ASANKATGAPD-------RKQDIGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIEEGKAYVDDTPADEMKAEREQRIESRHRKNPVEKNLQMWEEMKRGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKLRALCKKVIDPVAPRYVALLKKEVIPVNILDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNPDGKITSLDAKLNLENKDYKKTTKITWLAETTQALPVP-AVCVTYEHLITKPVLGKDEDFKQYVNKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTKVEISK---KETGSAPKERPAAAVSAPCAAAEDAAILYS-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDAVRDLKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYRPGNPPTAAVQTVSTKSPSNTGEYT------------SLYNKVAAQGELVRKLKAEKAPKAKINDAVECLLSLKAEYKEKTGKEYVPGQLPAS--QNSHSSPVS----NAKPVGSETPEAKLLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATG-----------------------AEDKDKKKKEKENKSEKQNK--------------------------------------------------------------------------------------------------------PQKQNDGQGKDSSK-SQGSGLSSG----GAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQGALEKEKNHIADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTLEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPK-TPGEKQFAYQCSWGLTTRTIGVMIMVHGDNMGLVLPPRVASVQVVVIPCGITNTLSEEDREALMAKCNEYRRRLLGADIRARVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAESKLKGVLEDIQLNLFTRASEDLKSHMVVSDTLEDFQKVLDSGKVAQIPFCGEIDCEDWIKKTTARDQD-----VEPGAPSMGAKSLCIPFNPLCELQPGAMCVC--GKNPAKFYTLFGRSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGC7-1", "uniprot_id": "SYEP_MOUSE", "id": "Q8CGC7-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKE---NLLRVSETVAFTDVNSILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWD---VSGNRATVAPD-------KKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFN-------KKVIDPVAPRYVALLKKEVVPVNVLDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWLAESTHALSIP-AVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVEISK---KETSSAPKERPAPAVSSTCATAEDSSVLYS-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDVVRELKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYKPGNPSAAAVQTVSTKSSSNTVEST------------SLYNKVAAQGEVVRKLKAEKAPKAKVTEAVECLLSLKAEYKEKTGKDYVPGQPPAS--QNSHSNPVS----NAQPAGAEKPEAKVLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATG-----------------------AEDKDKKKKEKENKSEKQNK--------------------------------------------------------------------------------------------------------PQKQNDGQGKDSSK-SQGSGLSSG----GAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPK-TPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQD-----VEPGAPSMGAKSLCIPFNPLCELQPGAMCVC--GKNPAKFYTLFGRSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07814-1", "uniprot_id": "SYEP_HUMAN", "id": "P07814-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "MATLSLTVNSGDPPLGALLAVEHVKDDVSISVEEGKE---NILHVSENVIFTDVNSILRYLARVATTAGLYGSNLMEHTEIDHWLEFSATKLSSCDSFTSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAFQSVGTKWD---VSTTKARVAPE-------KKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFN-------KKVIDPVAPRYVALLKKEVIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWLAETTHALPIP-VICVTYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEATK---NETSAPFKERPTPSLNNNCTTSEDSLVLYN-----------------------------------------------------------------------------------------------------------------------------------------------------RVAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQEYKPGNPPAEIGQNISSNSSASILESK------------SLYDEVAAQGEVVRKLKAEKSPKAKINEAVECLLSLKAQYKEKTGKEYIPGQPPLS--QSSDSSPTR----NSEPAGLETPEAKVLFDKVASQGEVVRKLKTEKAPKDQVDIAVQELLQLKAQYKSLIGVEYKPVSATG-----------------------AEDKDKKKKEKENKSEKQNK--------------------------------------------------------------------------------------------------------PQKQNDGQRKDPSK-NQGGGLSSS----GAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPK-IPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQD-----LEPGAPSMGAKSLCIPFKPLCELQPGAKCVC--GKNPAKYYTLFGRSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARK1-1", "uniprot_id": "A0A8M3ARK1_DANRE", "id": "A0A8M3ARK1-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "-MALNLTFNSSNPPLGALLTAEHVKGSVNLSVEEGKD---TMLHVSDQVQFSDVNSITRYLARVAPALGLYGSNMMEQTEVDHWLEFSARRLCGQSDLSSALADLDKALALRTFLVGRSVTLADLCIWAALKGNGESQAKP---SSHPHLCRWFSFLSSQVPFSSVGSKWASKVSASKAASVEKD-------KKQDLGKFVELPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQHYQVTFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLQIKPDQFTYTSDHFPTILRMGEKLLQEGKAYIDDTPPDIMKQEREQRAESRNRNNSVEKNMQMWEEMKKGTEFGQTCCMRAKIDMNSNNGCLRDPALFRCKNAAHPRTGTTYKVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWVIEALGLRKPYIWEYARLNLNNTVLSKRKLTWFVDKGYVDGWDDPRFPTVRGVLRRGMTVDGLKQFIAAQGGSRSVVNMEWDKIWAFNKKLPVSCKKVIDPVAPRFTALLSSQVIPVCVSEAKETMKEVPKHPKNADVGLKQVWYGPKVFIEGADAETFTEGEIVTFINWGNIIITKIHRDSSGAILSLDGHLNLENTDYKKTTKITWLAESSRASFVP-TVCVNYQHLITKPVLGKDDDFKDYINKNSKIEEKMIGDPCLKDLKKGDIIQLQRRGFYICDQPYEPISPHSCRESPCVLLYIPDGHTKEMPTAGSKDKSKSQPAKPVKAEPAPPSKAKSAPSSNPTPSAPGDASVILSNIMAQGDAVRQLKTEKAPKEQVDAAVKQLLALKSEFKQLTGQEYKPGMTLPASAPVQKSSAPTLAAAPGPASTGCPFTRVSEQGELVRKLKAEKAPKEQIDAAVKQLLAFKAEFKQLTGQDYKPGMAPPTASPPEPAPSSNSSPAGIYERVSEQGELVRKLKAEKAPKDQVDAAVKQLLALKAEYKQGTGQDYKPGVPTAKASPASSSSPAQLTVASTPAASAPSDSSPQAIYDRVSQQGDLVRKLKTEKAPKDQVDAAVKQLLNLKAEYKQQTGQEYKPGAPPSSGSATAQSNPTPPQSSSSQPQSSSSPQAQALFSDIAQQGEQVRRLKTEKAPKEQVDKAVKTLLELKGQYKALTGEEYKPVTTPGN----------------------SGGEDKSRKERENKSEKQGG--------------------------------------------------------------------------------------------------------GGGGGRKQQKGGEKPQQGQESGAG----GAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKAEMIEYYDVSGCYVLRPWSYSIWDAIKEFFDREIKKLGVENCYFPMFVSQAALEKEKTHIADFAPEVAWVTRSGKTELAEPIAVRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHTAFATKEEATEEVLQILDLYARVYEELMAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSRMFEIVFEDPK-KPGEKQLAYQNSWGITTRTIGVLTMVHGDNMGLVLPPRVACLQVIIIPCGITATLPEAEKDLLLDQCSKYLSRLQKADIRVKADLRDNYSPGWKFNHWELKGVPIRFEVGPKDLKQGQFVAVRRDTGEKITVKEADAEKKIPNLLEEIQNNLFKRASDDLNKHMVVADTMEQFQKDLDQGRIVQIPFCGGIECEDWIKKTTAKDQD-----LEPGAPSMGAKSLCIPFKPLKNLQAGQMCVS--GKEPAQYYTLFGRSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38708-1", "uniprot_id": "YHI0_YEAST", "id": "P38708-1", "name": "Putative proline--tRNA ligase YHR020W", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVSEAFAKLCVNEKPPAESAVAVKSLV-----FKPKTPKSATP-VPIVVVALQSTTTPSALIANAT-----------------------------SSKDPRLARDDLVK------QAFQSESARAFILG---------------------DLANATSNFHLLIDHELGTVDGDTILQLNDSTYMKK------SDMMKFLNNFE------------------------------------------DSQKVVDFSQEVSKE--------------------------------------------------------------------------------------------------------TATEGKKQQK---K-QQPSKAGTA----AAAAAAALEDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPFDQP-VLNEGQKCIK--CERIAVNYCMFGRSY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28668-1", "uniprot_id": "SYEP_DROME", "id": "P28668-1", "name": "Bifunctional glutamate/proline--tRNA ligase", "aln": "-MSIKLKANLNNPPISGLATAHLINGTVPVEIVWSKEETSLQFPDNRLLVCHSNNDVLRALARAAPDYKLYGETAIERTQIDHWLSFS---LTCEDDISWALSFLDKSIAPVTYLVANKLTIADFALFNEMHSR---YEFLAAKGIPQHVQRWYDLITAQPLIQKVLQSLPEDAKVKRSPQSSKEQTPAKTGERKQEGKFVDLPGAEMGKVVVRFPPEASGYLHIGHAKAALLNQYYALAFQGTLIMRFDDTNPAKETVEFENVILGDLEQLQIKPDVFTHTSNYFDLMLDYCVRLIKESKAYVDDTPPEQMKLEREQRVESANRSNSVEKNLSLWEEMVKGSEKGQKYCVRAKIDMSSPNGCMRDPTIYRCKNEPHPRTGTKYKVYPTYDFACPIVDAIENVTHTLRTTEYHDRDDQFYWFIDALKLRKPYIWSYSRLNMTNTVLSKRKLTWFVDSGLVDGWDDPRFPTVRGIIRRGMTVEGLKEFIIAQGSSKSVVFMNWDKIWAFN-------KKVIDPIAPRYTALEKEKRVIVNVAGAKVERIQVSVHPKDESLGKKTVLLGPRIYIDYVDAEALKEGENATFINWGNILIRKVNKDASGNITSVDAALNLENKDFKKTLKLTWLAVEDDPSAYPPTFCVYFDNIISKAVLGKDEDFKQFIGHKTRDEVPMLGDPELKKCKKGDIIQLQRRGFFKVDVAYAPPSGYTNVPSPIVLFSIPDGHTKDVPTSG--LKVNAPDAKATKKASSPVSSSGQASELDSQISQQGDLVRDLK-------------SKKAAKDQIDVAVKKLLALKADYKSATGKDWKPGQTSASSAPVPAASSSSAN-----------------------------------------------------------------------------DAVSVNASIVKQGDLVRDLKGKKASKPEIDAAVKTLLELKAQYKTLTGQDWKPGTVPTTAAPSASAAPSVGVNDSVA-----------QILSQITAQGDKVRELKSAKADKATVDAAVKTLLSLKADYKAATGSDWKPGTTAPAPAAAPVKVKQE-----KNPDPASVLTVNTLLNKIAQQGDKIRQLKSAKSEKSLVEAEVKLLLALKTDYKSLTGQEWKPGTVAPAPTTVNVIDLTGGDSGSDVGSVLSKIQAQGDKIRKLKSEKAAKNVIDPEVKTLLALKGEYKTLSGKDWTPDAKSEPAVVKKEASPVSMASPAKDELTQEINAQGEKVRAAKGNKAAKEVIDAEVAKLLALKAKYKEVTGTDFPVAGRGGGGGGGSAKKAPKEAQPKPAKPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDPE--TQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEE-----AEPGAPAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46655-1", "uniprot_id": "SYEC_YEAST", "id": "P46655-1", "name": "Glutamate--tRNA ligase, cytoplasmic", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSTLTINGKAPIVAYAELIAARIVNALAPNSIAIKLVDDKKAPAAKLDDATEDVFNKITSKFAAIFD-----------------NGDKEQVAKWVNLAQKELVIKNFAKLSQSLETLDSQLNLRTFILG---------------------GLKYSAADVACWGALRSNGMCGSIIKNKVDVNVSRWYTLLEMDPIFGEAHDFLSKSLLELKKSANVG----------------------------KKKETHKANFEIDLP--------------------------------------------------------------------------------------------------------DAKMGEVVTRFPPEPSGYLHIGHA----KAALLNQYFAQAYKGKLIIRFDDTNPSKEKEEFQDSILEDLDLLG--IKGDRITYSSDYFQEMYDYCVQMIKDGKAYCDDTPTEKMREERMDGVASAR-----RDRSVEENLRIFTEEMKNGTEEGLKNCVRAKIDYKALNKTLRDPVIYRCNLTPHHRTGSTWKIYPTYDFCVPIVDAIEGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVRTLLSKRKLQWMVDKDLVGNWDDPRFPTVRGVRRRGMT---VEGLRNFVLSQGPSRNVINLEWNLIWAFNKKVIDPIAPRHTAIVNPVKIHLEGSEAPQEPKIEMKPKHKK------NPAVGEKKVIYYKDIVVDKDDADVINVDEEVTLMDWGNVIITKKNDDGSMVAKLNLEGDFKKTKHKLTWLADTKDVVPVDLVDFDHLITKDRLEEDESFEDFLTPQTEFHTDAIADLNVKDMKIGDII---------------QFERKGYYRLDALPKDGKPYVFFTIPDGKSVNKYGAKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . .. * . . .: . . : * *. : . . : . :: :: . : . . * . : : * * : : .: : .::: *: * : . :: :* : : :.* :. *:. : . :: . :* .. .: .:: * *.: : . : : : . :. ..* :: : .:: **.. .** ::. * . :. ..: . .*. : : .. : * * : ..*.: : *: * .. :: * * : : : . * . ..: : . : : *: * .. . : : : * : . : . . :: : .: :* . : : : . :* . ", "identical_positions": 34, "similar_positions": 153, "identity": "1.84%" }, { "cls_id": "homologset.agr.FB:FBgn0005677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LX95-1", "uniprot_id": "F1LX95_RAT", "id": "F1LX95-1", "name": "", "aln": "---------------------------------MAVSAPP--------VISATSTSAGVPGGLFRAEPLYSSPGE---------PPRLTPNMINSFMASN--------------------------------------------------------------------------------------------------HNGSVVGGGIGGGSGGTSNTNTN-ECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQDNARLLPHAVPG----------------------LLSPGLITPTG------------ITAAA----------MAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSTTGGSESSWDKEKIQSPLAAPGAQHGIAHAALAGQPGLGGAPTLNPLQQNHLLSNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSP--------------------------------LSRAGASVIKERIPESPSPAPSLEESHRPGSQTSSHPSSSVSSSPSQMDHQSERMVMMPNNREEIIIDQDNGQSIKKFQRDNKDIQLSQHHL-LNTFLHWIELAPLSKKSLLHQKEVPAQIPMMKSPLDKIQLAPG-QALPPGFPGPFIFADS-----LSSVETLLTNIQVNNISINKINGLLKVALDNARIQEKQIQQEKKELRIELYREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFES----------------------------------------------------KRREQVEQALKQATSGDSGLRMLKDSGIPDIEIENSGTPHDSA-AMQGGNYYCLAMAQQLCSA---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925Q8-1", "uniprot_id": "DACH2_MOUSE", "id": "Q925Q8-1", "name": "Dachshund homolog 2", "aln": "---------------------------------MAVSAPP--------VISATSSSAGVPGGLFRAEPLYSSPGE---------PPRLTPNMINSFMANN--------------------------------------------------------------------------------------------------HNGSVLGGGIGGGSGGSSNTNTN-ECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQDNARLLPHAVPG----------------------LLSPGLITPTG------------ITAAA----------MAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSTTGGSESSWDKDKIQSPLAASGPQHGIAHAALAGQPGLGGAPTLNPLQQNHLLSNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSP--------------------------------LSRAGASVIKERIPESPSPAPSLEESHRPGSQTSSHPSSSVSSSPSQMDHHSERMVMMPNNREELIVDQDNGQSIKKFQRDNK-------------------------------EEVPAQIPVMKSPLDKIQLAPG-QALHPGFPGPFIFADS-----LSSVETLLTNIQG----------LLKVALDNARIQEKQIQQEKKELRIELFREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFES----------------------------------------------------KRREQVEQALKQATSGDSGLRMLKDSGIPDIEIENSGTPHDSA-AMQGGNYYCLAMAQQLCSA---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NX9-1", "uniprot_id": "DACH2_HUMAN", "id": "Q96NX9-1", "name": "Dachshund homolog 2", "aln": "---------------------------------MAVSASP--------VISATSSGAGVPGGLFRAEPLYSTPRE---------PPRLTPNMINSFVVNN--------------------------------------------------------------------------------------------------HSNSAGGGGRG-------NTNTN-ECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQENARLLTHAVPG----------------------LLSPGLITPTG------------ITAAA----------MAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSP--------------------------------LSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERM-----------------------------------------------------------EEVPVQIPIMKSPLDKIQLTPG-QALPAGFPGPFIFADS-----LSSVETLLTNIQG----------LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFES----------------------------------------------------KRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSA-AMQGGNYYCLEMAQQLYSA---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T9A7-1", "uniprot_id": "A0AB32T9A7_DANRE", "id": "A0AB32T9A7-1", "name": "", "aln": "---------------------------------MAVSATPP-------VLSPTSTPGGAS--LFRPDSLYSSPAE---------SPRLTSSMINSFITG----------------------------------------------------------------------------------------------------GGSTNGNGPG-------GVHNN-ECKMVEVHGVKVASFTVDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDICPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNA----------------SSRPGRPPKRSLGVAMQDSSRLLPHSVHG----------------------LLSPGLLSPTG------------LTAAA----------MAEAMKLQKMKLMAMNNIHGAGSQNGTESENEELNSSAGGSESSWDKEKLQSPPSS-GAQHGLAHAALSAQHGLSGS-HLSSLQQSHLLANRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQMHSP--------------------------------LSRAGASVIKECVQDSPSPTPSLEEAPRPGSQPSSHPSSSVSSSPNPHTQSPERLVLNPTDGDLP--ERDTGINMKKMLKEK--------------------------------DEAQITLPMQKPGFEKLPLGT--QTLPPGFPAPFLFADG-----LSSVETLLTNIQAAQG-------LLKVAVDNARVQEKQVQQERKELKMELYREREMRESLERQLTSELHSRATIQKRLKKEKKAKRKLQEALEFES----------------------------------------------------KRREQVEQALKQATSPESLRMSLNEAVIPEVKSEHNGNQQENS-SVQENRPYSKPPIMY-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M0Y6-1", "uniprot_id": "F1M0Y6_RAT", "id": "F1M0Y6-1", "name": "", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASSASSSAATTVTSPGGGG--SGGGGGSGGNGGGGGG----SNCNPSLAAGSN---GGGGGVSAGGGGASSTPITASTGSSSSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPHSVPG----------------------LMSPGIIPPTG------------LTAAAAAAA---NAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSGGSWDKETLHSPPSQ-GSQAPVAHARIPAAYSLPVSHPLNHLQHSHLPPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSP--------------------------------PSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGD--------------LAGHDMGHESKRIHIEKDETPLSTPTARDSMDKLSLAGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQG----------LLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET----------------------------------------------------KRREQAEQTLKQAASADS-LRVLNDSLTPEIEADRSGGRADAERTIQDGRLYLKTTVMY-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYB2-1", "uniprot_id": "DACH1_MOUSE", "id": "Q9QYB2-1", "name": "Dachshund homolog 1", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASSASSSAAATVTSPGGGGGGSGGGGGSGGNGGGGG-----SNCNPSLAAGSS---GGG--VSAGGGGASSTPITASTGSSSSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPHSVPG----------------------LMSPGIIPPTG------------LTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSGGSWDKETLHSPPSQ-GSQAPVAHARMPAAFSLPVSHPLNHLQHSHLPPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSP--------------------------------PSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGD--------------LAGHDMGHESKRIHIEKDETPLSTPTARDSIDKLSLTGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQG----------LLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET----------------------------------------------------KRREQAEQTLKQAASADS-LRVLNDSLTPEIEADRSGGRADAERTIQDGRLYLKTTVMY-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI36-1", "uniprot_id": "DACH1_HUMAN", "id": "Q9UI36-1", "name": "Dachshund homolog 1", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSS---SCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPHSVPG----------------------LMSPGIIPPTG------------LTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSDGSWDKETLPSSPSQ-GPQASITHPRMPGARSLPLSHPLNHLQQSHLLPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSP--------------------------------PSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGD--------------LAGHDMGHESKRMHIEKDETPLSTPTARDSLDKLSLTGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQG----------LLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET----------------------------------------------------KRREQAEQTLKQAASTDS-LRVLNDSLTPEIEADRSGGRTDAERTIQDGRLYLKTTVMY-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NA80-1", "uniprot_id": "A0A8M1NA80_DANRE", "id": "A0A8M1NA80-1", "name": "", "aln": "---------------------------------MATPAALLPATPMAH-APPMSISAVVN----SSTPATLSPSPSVTP---AGPSLFRTELLSS-----------------------------------------ASPGIP---------------------------------------------------------IGSLPHKPVYSTPSPVENTPQNNECKMVEVRGAKLASFTVNGNELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFEVLYNDCTNA----------------SSRPGRPPKRTQNVTSPDSPHVLPHSVSG----------------------LMSSGLMSHTG------------LTAAT----------LAEAMK-KKIKLEVMNSYHGNNN-HSADSENGDITSSMG-----------------------------------------------------LELPFMMMPHPLIPVSLPPASVTMAMNQMNHLSTIASMAAAAQVQSV--------------------------------PSRMVTSVIKERVPDSPSPVPSLDDGRRSGSHLSSRQSSSVSSSPAHTESSSDRPHLHQNGLSLGHALLGLSPSAPPGPKEGD--------------LATHDTVHETKRASTEKEENVLCTPTSRDSYERLSHS--GPTLPPGFPAPLLFPEG-----LSSIETLLTNIQG----------LLKVAIDNARAQEKQVQLERTELKMELYRERELRETLERQLCVEQKNRALIQKRLKKEKKTKRKLQEALEVES----------------------------------------------------KRRDHAEQTLQRTTSCER-SPIHNDSQQ-ELETIHNTSKTDTERTIQDGRLFLKSTMMY-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP19-1", "uniprot_id": "Q8IP19_DROME", "id": "Q8IP19-1", "name": "", "aln": "MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHG-------MPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDAHAAVPASSTETLLRNIQS----------LLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNTKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..* .. : . .. . . . **::*: :* *:*:* :.. ::****.*:********************:* *:**.**********************: ***: *: ***.* ********** .:: *. *:: * . . **: : : : :* . . . . .. . .. . . :: : .* * .: .. ::*. .* . :* * * :.* . . * : . .: :: :::.:::. : : : .* *:. : :. ** **** *** ***** **** **:*:. *: **:::. ****:::.**:** * : * ***:::*:* : : *: * : .: ..* :. : : . :: .. . : . ", "identical_positions": 137, "similar_positions": 134, "identity": "12.48%" }, { "cls_id": "homologset.agr.FB:FBgn0005683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC11-1", "uniprot_id": "D3ZC11_RAT", "id": "D3ZC11-1", "name": "", "aln": "---MNENKPG----------------NSQSLACVFCRKNDDCPNKYGEKKTCEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCTVCKKNGASIGCVVPQCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYRDS---LPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDVRRCHCKEGREYNEPNSKWEIKRCQCCGSSGTHLACSS------LQSWEKNWECLDCRRIAYTS-DFQKAPKHPLANSTNVTVTDCLLEESSPKLPRQSTVAQ---QKELLSLKQEVQLSSTTCPSRKASCLTQRQGSKFRRDISTILIELGFQIKKKAKTLYIN---KANVWRSAVEQFQSQKFNPSYSIEVVYVNDNDEVGSKHPGSKQEFLSHLMHHLENSSVFEGS-LAKNLSLNSQAVKENLYYEAGKMLAISLVHGGPSPGFFSETLFKCLAYGPENALPTLDDVSDLDVAQIIIKIDTAADLNILKSVINEYYNYLEFSGCLRLMTTLSDKYMLVKDILFYQVIKRVKAPFESFKQGLKTLGVLEKIQAYPEAFYNILCHKPESLSAKNLSDLFTIHK-------LPDVKTSRFWNSYLQAVEDGKSATTLEDILHFATGCSSVPPTGFKPAPSIECLH-----GDFPVANKCNNCLALPVTNTYEEFQENMDFAIRDSIRLEKEERSHLLPRTLNVSSNEEMLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJY2-1", "uniprot_id": "G2E3_MOUSE", "id": "Q5RJY2-1", "name": "G2/M phase-specific E3 ubiquitin-protein ligase", "aln": "---MNENKPD----------------NSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYSSS---LPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDIRRCHCKKGRDYNEPNSKWEVKRCQSCGSSGTHLACSS------LQSWEQNWECLDCRRITYTS-DFQKAPKHPLANSTNVTVTDCLLEESSSKLPRQSTVAQ---HKELL-----------------------RQGSKFRRDISTILIELGFQIKKKTKTLYIN---KANVWRSALEQFQSQKFNPSCSIDVVYVNGN-EVGSQHLGSKQEFLSHLMHHLENSSVFEGS-LAKNLSLNSQAVKENLYYEVGKMLAISLVHGGPSPGFFSETLFNCLAYGPENTLPTLDDVSDIDVAQIIIKIDSATDLNILNSVISQHYNYLEVSGCLRLTTSLSDKFMLVKDILFYHVINRVKAPFESFKQGLKTLGVLEKIQTYPEAFYKILCHKPENLSAKNLSDLFTIHS-------VADVQTLRFWNSYLKAIEDGKSATTMEDILIFATGCSSVPPTGFKPSLSVECLH-----VDFPVADKYRNHLVLPATNTYEEFQENMDFTIRDTLRLEKEERSHILPRTLNVSSNEEMLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L622-1", "uniprot_id": "G2E3_HUMAN", "id": "Q7L622-1", "name": "G2/M phase-specific E3 ubiquitin-protein ligase", "aln": "---MNESKPG----------------DSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRES---LPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSS------LRSWEQNWECLECRGIIYNSGEFQKAKKHVLPNSNNVGITDCLLEESSPKLPRQSPGSQ---SKDLL-----------------------RQGSKFRRNVSTLLIELGFQIKKKTKRLYIN---KANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGS-LSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHT-------LPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLH-----VDFPVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW58-1", "uniprot_id": "Q8AW58_DANRE", "id": "Q8AW58-1", "name": "", "aln": "MKALNEKSAEIKL-------------QDRDLICCLCKRSENNKEKYGEKVHLEQHNLAVHFFCLLMSSGICQRGEEDEDVYGFLVGDIKKEIRRSSRLRCFHCKKAGASVGCSIKSCRQMVHMPCGLEQEFVFQFTGLFPSFCKKHAPTQSCDS-SHSLP---HSCSICLDPIEPILSYHVLKCPACHGSWFHRKCVQNYAHSAAMFFFKCTLCNNKEQFQQEMLRMGIYIPERDASWELEENAFVELLQVYHRCDAVKCLCHKGREHSSQSGYFEIVLCKLCGSRGTHRKCSN------IRVYEADWMCADCK--------TAAEGKTSLPLPNHVESPLAIRQERKRLFKSISDIHSSIVAK--------------------------RQCVPATS--PEVLMDLACQISQQQFTEVLVGDDDGGVMEAALQVLRQSDFNPCCTLSVKFSKDK---LNNNIRNQRRFLRRLVSKLQVSDIFEGSDGAKNLALNSKALRDDLYFDVGSLLALSLVHGGPPLGFFSPALYHSLFNYPKNYRPTLEDLGDTAFGHKIRQIAEAKSMKELRHAMKSASQYLEAAGCWRKISKLSEKDMLVEDVLNFYLIIRLQLPLQRFREGLRTLGMFEQVQMCSETFFPVFCGPVERLTAESVMELFTTRLSEEKEKQVLEKTTISFWKQYLHECEEGQCAASLEDLLTFATGTDLVPAIGFKPTPSISFLSSPDNLCAFPQSNCDANHLILPTLPSYQLFKKHLDYTVCQFSVMQDI--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AXW4-1", "uniprot_id": "PHF7_RAT", "id": "Q6AXW4-1", "name": "E3 ubiquitin-protein ligase PHF7", "aln": "MRTIKEKKEHPRLRKTARTKKVTHRKLSSGPVCLLCFQEPGDPEKLG--EFLQKDNLCVHYFCLILSSKLPQKGQPNRGLHGFMPEDIKKEAARASRKVCFVCKRKGAAIRCQKDQCVQNFHLPCGQERGCLSQFFGEYKSYCGKHRPTQNIHQRSFG-----ESCVLCCEDLS-RASVENIRSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSS------LRPNSKKWECNECL---------------PASTEDSVSENLGDTPCCSSTFCP----------------------------------------------------------------------------------------------HEPFLRATSLEENPGSSWTNWLQPSLLEKPESS---SGS---SCQSWRSKGIKVTKDCKKSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAG9-1", "uniprot_id": "PHF7_MOUSE", "id": "Q9DAG9-1", "name": "E3 ubiquitin-protein ligase PHF7", "aln": "MKTLKEKNKHPRLRKTIRTKKVTQRKLSSSPVCLLCLQEPGDPEKLG--EFLQKDNLCVHYFCLILSSRLPQKGQPNRGLHGFMPEDIKREAVRASKKICFVCKKKGAAIRCQNDQCVQNFHLPCGQERGCLSQFFGEYKSYCRKHRPTQNIHQGSLGE----ESCVLCCENLS-RTSVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYRHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSS------LRPNSKKWECNECL---------------PASTTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWX1-1", "uniprot_id": "PHF7_HUMAN", "id": "Q9BWX1-1", "name": "E3 ubiquitin-protein ligase PHF7", "aln": "MKTVKEKKECQRLRKSAKTRRVTQRKPSSGPVCWLCLREPGDPEKLG--EFLQKDNISVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGE----ESCILCCEDLS-QQSVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRDAAWELEPGAFSDLYQRYQHCDAPICLYEQGRDSFEDEGRWCLILCATCGSHGTHRDCSS------LRSNSKKWECEECS---------------PAAATDYIPENSGDIPCCSSTFHP----------------------------------------------------------------------------------------------EEHFCRDNTLEENPGLSWTDWPEPSLLEKPESS---RGR---RSYSWRSKGVRITNSCKKSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKW2-1", "uniprot_id": "PIE_DROME", "id": "Q9VKW2-1", "name": "Pineapple eye protein", "aln": "---MED---------------------NKELQCLICKYSDTDDLVFG--EWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDR--CRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSG-YYLRCIWCRS-ERFRDSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRTYNRLS--WVILCCSSCAATSAHLKCLVGALRLPKKRERTDFKCSMCLDVER------RIAEGPARTTEETNADGDNQVDGSFYVQKLGPDAATR------------------------------------------------------------------SLTQTPVFSEEDESERSSNITVIFSQPKSNATSERLSLSPPQEEMIVEIPDSPEASPKTSIDENHSPQPIARRDTS--DSPQPIAASEIPDSPQP----------------TAASEIPDLPQTTAINVNPELTQQTALNTIPHSPQPEASFSTQLVSQTFDCPQPQEQAVAKAPNSPSLPKEDPNTLLVLKSGFQCP---------GEPFFYLVIYEFEHGTCMG---------------ECIGTCVLRFKEDDPRIQDTSQAALERVNITPDDVWCRSE------------------------------DRGIFEHIEKFHEWYRSEGFS------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . * :* * *: **::**::*: : *:* . .. **: **:.* :.: * *:: **:: * * *: ** :. : :* . : *:* . * : .* :* . : : .* . *:.*:: * .:. .:::* *.. . * ..: .:.:*::**:** : .*: :* : :** * .** . : : * *.: .:* * : .: * * ", "identical_positions": 56, "similar_positions": 84, "identity": "7.11%" }, { "cls_id": "homologset.agr.FB:FBgn0005695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NEA9-1", "uniprot_id": "GMCL2_HUMAN", "id": "Q8NEA9-1", "name": "Germ cell-less protein-like 2", "aln": "MGSSSSRVLGQPRRALAQQEQGARARGSARRPDTGDDAASYGFCYCPGSHKRKRSSGA----CRYCDPDSHREEHEEEGDKQQPLLNTPARKKLRSTSKYIYQTLFLNGENSDIKICALGEEWRLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVDALQVAFGSLYRD-DVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETINVKTVCGYYTSVEIYGLDSVKKKCLEWLLNNLMTHQNVK--LFKELGINVMKQLIGSSNLFVMQVEMDVYTTLKKWMFLQLVPSWN--------------------GSLKQLLTETDVWFSKQRKDFEGMAFLETEPGKPFVSVFRHLRLQYIISDLASARIIEQDGIVPSEWLSSVYKQQWFAMLRAEQDRE-VGPQEINKEDLEGNSMRCGRKLAKDGEYYWCWTGFNFGFDLLVIYTNGYIIFKRNTLNQPRSGSVSLRPRRSIAFRLRLASFDSSGKLVCSRTTGYQILILKKDQEQVVMNLDSRFLTFPLYICCNFLYISPEKGIENNRHPENPEN----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96IK5-1", "uniprot_id": "GMCL1_HUMAN", "id": "Q96IK5-1", "name": "Germ cell-less protein-like 1", "aln": "MGSLSSRVLRQPRPALAQQAQGARAGGSARRPDTGDDAAGHGFCYCAGSHKRKRSSGS----FCYCHPDSETDEDEEEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVEALQVAFGSLYRD-DVLIKPSRVVAILAAACLLQLDGLIQQCGETMKETVNVKTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQNVE--LFKELSINVMKQLIGSSNLFVMQVEMDIYTALKKWMFLQLVPSWN--------------------GSLKQLLTETDVWFSKQRKDFEGMAFLETEQGKPFVSVFRHLRLQYIISDLASARIIEQDAVVPSEWLSSVYKQQWFAMLRAEQDSE-VGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRTTGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEK--KN-------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q920G9-1", "uniprot_id": "GMCL1_MOUSE", "id": "Q920G9-1", "name": "Germ cell-less protein-like 1", "aln": "MGALSSRVLR-PAGRTEQPEPTPGAGGAARRSDAGEDAG-HSFCYCPGGRKRKRSSGT----FCYCHPDSETDDDEDEGDEQQRLLNTPRRKKLKSTSKYIYQTLFLNGENSDIKICALGEEWSLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDIEALQVAFGSLYRD-DVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETISVRTVCGYYTSAGTYGLDSVKKKCLEWLLNNLMTHQSVE--LFKELSINVMKQLIGSSNLFVMQVEMDVYTALKKWMFLQLVPSWN--------------------GSLKQLLTETDVWFSKWKKDFEGTTFLETEQGKPFAPVFRHLRLQYIISDLASARIIEQDSLVPSEWLAAVYKQQWLAMLRAEQDSE-VGPQEINKEELEGNSMRCGRKLAKDGEYCWRWTGFNFGFDLLVTYTNRYIIFKRNTLNQPCSGSVSLQPRRSIAFRLRLASFDSSGKLICSRATGYQILTLEKDQEQVVMNLDSRLLIFPLYICCNFLYISPEKRTESNRHPENPGH----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2CGC2-1", "uniprot_id": "A2CGC2_MOUSE", "id": "A2CGC2-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKN--IDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BFZ7-1", "uniprot_id": "A2BFZ7_MOUSE", "id": "A2BFZ7-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7MU81-1", "uniprot_id": "L7MU81_MOUSE", "id": "L7MU81-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7MU83-1", "uniprot_id": "L7MU83_MOUSE", "id": "L7MU83-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WSN2-1", "uniprot_id": "A0A087WSN2_MOUSE", "id": "A0A087WSN2-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A571BD55-1", "uniprot_id": "A0A571BD55_MOUSE", "id": "A0A571BD55-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2CG71-1", "uniprot_id": "A2CG71_MOUSE", "id": "A2CG71-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLQPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2CG92-1", "uniprot_id": "A2CG92_MOUSE", "id": "A2CG92-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WR44-1", "uniprot_id": "A0A087WR44_MOUSE", "id": "A0A087WR44-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8JKF6-1", "uniprot_id": "B8JKF6_MOUSE", "id": "B8JKF6-1", "name": "", "aln": "MGLLVSRFLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0A0MQP3-1", "uniprot_id": "A0A0A0MQP3_MOUSE", "id": "A0A0A0MQP3-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A571BG45-1", "uniprot_id": "A0A571BG45_MOUSE", "id": "A0A571BG45-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QMW9-1", "uniprot_id": "J3QMW9_MOUSE", "id": "J3QMW9-1", "name": "", "aln": "MGLLVSRVLSCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BHG6-1", "uniprot_id": "A2BHG6_MOUSE", "id": "A2BHG6-1", "name": "", "aln": "MGLLVSRVLSCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A571BG86-1", "uniprot_id": "A0A571BG86_MOUSE", "id": "A0A571BG86-1", "name": "", "aln": "MGLLVSRVLSCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QMS5-1", "uniprot_id": "J3QMS5_MOUSE", "id": "J3QMS5-1", "name": "", "aln": "MGLLVSRVLSCRDSSLLEPQPEDIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4J2B9-1", "uniprot_id": "A0A0R4J2B9_MOUSE", "id": "A0A0R4J2B9-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEGIAGAS----------------YIPVSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QNQ5-1", "uniprot_id": "J3QNQ5_MOUSE", "id": "J3QNQ5-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEGIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QN64-1", "uniprot_id": "J3QN64_MOUSE", "id": "J3QN64-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A140T8Q5-1", "uniprot_id": "A0A140T8Q5_MOUSE", "id": "A0A140T8Q5-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QML3-1", "uniprot_id": "J3QML3_MOUSE", "id": "J3QML3-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2CFD5-1", "uniprot_id": "A2CFD5_MOUSE", "id": "A2CFD5-1", "name": "", "aln": "MGLLVSRVLRCRDSSLLEPQPEAIAGAS----------------YIPGSRKRKRNS------LEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVA--LYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWN--------------------GTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV-IGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQR--CQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8J8Y4G1-1", "uniprot_id": "A0A8J8Y4G1_RAT", "id": "A0A8J8Y4G1-1", "name": "", "aln": "MGLLNSRVLRSGDSSLVEPQPEATAGPS----------------GQSGSRKRKLSN------SVNLGPSPDIHGPQNQGFSLHQVLNYIYRKRVKISSNYAYENLFLNGNDSDIKICALGRTWCLHKVFLCHSGYFANILKGIWKESRNGVIRLLIRNEDIDTRSLHFVFGSLYTDENLSLTPLEVPRVLAAACLLRVDRVIRQCEEIMKTTINRNTACSYYLAAETYRLKAVKTECFQWLLHNLMVHPSVA--LYKAVDLKLMYLLTSSSHLLVMQKEIDVYTTLKTWMFLYLNPCWN--------------------GTMKELLDHTNNWLYTYMGYIDNISFLESEEGLIFQPVFKKLRFQHIICDLASTSVLERDRLIPAEWLSPIYKHQWLTLLRAQEYGT-IGPQTINEEELEQNTMRCGKRIPRDGRYTWKWSAGRLCFPLRVTFTSHGVILRQR--HQECDGSSCQNHIRNVVFRITLVCFDSNEKITFIKTTGYKILTFEFNEEQIVMKLDAEVLTFPLYIFGNFLFLNLGNAENK-------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K031-1", "uniprot_id": "A0A0G2K031_RAT", "id": "A0A0G2K031-1", "name": "", "aln": "MGALSSRMWSGRNPEEDEPAREGAAREEE---------------AAVGAGEQAGPAVVQEEQASELPGVSTGQAGHKRKASPGGPKAKVPRKKMDK-SRGIYESLFLGGENSDVKICAFQQEWCLHRAYLCRSGYFSSMFCGAWLETNMNTIEMQMPDENIDREAFHEVLGFLYSR-RIAIPPSRVIAILATASMLQLDELIQQCEDMMRATVRTDTVCSYYYSAENYGLQSIRYICRQWLLDNLMIRQNDE--LLLEINLNLMRELIASSDLLVVGVEMDVYITLKKWMYLQLEARTC--------------------SESQRAVLPAQLCFAKFKSESDSSPFLDSNQGRTFVPVFQKLRLPYIICDLPSAHVIDQDGLIPATWLTPVYKEQWLALLRAEQSRE-LGPMDIYVSDIGGNSMRCGGQLISDEQCSWTWTGFNFGWDLVVCYVNKRIVFRRSAMNKSCGLGVSLLWQRKVAFRLRVISLDSTGKAVLRRETEYSVLSLRKDQELEVVNLQNQDLTFPMYVACNFLYLPGESGAGPSGESSRSPMN---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01820-1", "uniprot_id": "GCL_DROME", "id": "Q01820-1", "name": "Protein germ cell-less", "aln": "MGQIVGSMHMNVAEVFSN------------------------------RRKRKRST----------------DSSLGKDDPAQLDTTQPKKKKLLTTTQYIYKALFKEEKNSDVAVMALDKVWHLHKVYLSQSPYFYTMFNGTWREAQQNFIQITILDDRITVASLDAVFGSMYSD-EIEIESADVISVLATATLFHLDGIIDKCAEVMVDNISPETAIQYYEAACQYGVVGVKKSTFQWFQINLLSIYSKQPNLLRHISIELMSALTASPDLYVMQTEFSLYTLLRTWMFLRLHPDYDPEDPVQRAEALKTQELLVNAGVETHAPSGDVVQWTYFTSRSEERSFLATPEGQPYVKVFQKLRTQYLTNHYMDLKIIYNDNIIPKEWLYRHIHNHWDALLRIDHGQEDCSPQQLDDEQFFENCMRCGRMLLEPGYQKWRWTGFNFGMDLILIMDSRRLNIRRHH-RHEHERVLSLQTKRKFMVRTTVTSINAQRQAVFTQTSEICSLSLEKNEEVPLMVLDP-KLVHPLLISINMLVVMPPNQSFKEIVPLSEEATTSLSIPISEIGANSDRPLSPSSADDSAVFIGDSEPSTPSSPAPRPRIAWSASETGAICGQLAC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . : :: . . *:: :. *: ** .:**: : *: . * **: :*.:* ** .:: . * *: . *.: : : * :: .:* :* : : . * **:* ::::* :* :* * .: *. ** :. * : .:: :*: **: . * :.:::* * *..* *: *:.:* *: ** * * . . . : .** : * : **::** :: . . :: .* ::* ** :.:* ::*: :. .* : .:: **** : * *: .: * : : ::: : . *.. .* : .::: : : : * :. .:* :: *: * .*: : *:* : . ", "identical_positions": 80, "similar_positions": 138, "identity": "12.94%" }, { "cls_id": "homologset.agr.FB:FBgn0005696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89043-1", "uniprot_id": "DPOA2_RAT", "id": "O89043-1", "name": "DNA polymerase alpha subunit B", "aln": "------------------MAVSTQQLAEELQIFGLDCEDSLLEKLAELCTLYRQTEE-RMVSELIAFCTSAGK-----SCLTGEILSSFEHEVLNKKLSK-------ACHSAS-KDNRHAGARDIVSIQELIEAEEEEETLLSAYTTPSKGPHKRVSSTPETPLTKRSISTRSPHQLLSPSSFSPSATPSQK------YSSRTNRGEVVTTFG---SAQGVSWSGRGGSGS-ISLKVMGYPEPLTSS----YKTMFQQLPDIREVLTCKIEELGSELKEHYKIEA---------FTPLLVPAQEPVILLGQIGCDSNGRLNSKS---VILEGDREHSSGAQIPVDVSELKDYSLFPGQVVIMEGFNTTGRRLTATKLYEG-------VPLPFYQPTEEEGDFEQTMVLVACGPYTTSDSITYDPLLDLISTIN-HDRPDVCILFGPFLDAKHEQVENCKLTSP---------FEDIFKQCLRTVIEGTRSSGSHLVFVPSLRDVHHEPVYPQPPFTFSELPREDKKRVQFVSEPCNLSINGVMFGLTSTDLLFHIGAEEICSSSGTSDRFSRILKHILTQRSYYPLYPPH--------------EDMAIDYENFYTYAQLP-----------------VTPDVFIVPSELRYFVKDIFGCVCMNPGRLTKG-QVGGTFGRLYLRRQPKGTDSEGRQGLSVAAQVVRI-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33611-1", "uniprot_id": "DPOA2_MOUSE", "id": "P33611-1", "name": "DNA polymerase alpha subunit B", "aln": "------------------MAVSTQQLAEELQIFGLDYEDSLLEKLAELCVLYRQTED-GMVSELIAFCTSAGK-----TCLTVDILNSFEYEVLNKKLSK-------AWHSAS-KDSGHAGTRDIVSIQELIEAEEEEETLLSSYTTPSKGPLKRVSSTPETPLTKRSVAARSPRQLLSPSSFSPSATPSQK------YTSRTNRGEVVTTFG---SAQGLSWSGRGGSGS-VSLKVVGDPEPLTGS----YKAMFQQLMGVREVLTSKIEELGSELKEHHKIEA---------FTPLLVPAQEPVILLGQIGCDSNGKLNSKS---VILEGDQEHSYGAQIPVDLSELKEYSLFPGQVVIMEGFNTTGRRLTATKLYEG-------VPLPFYQPTEEEGASEQTMVVVACGPYTTSDSITYDPLLDLIAIIN-RDQPDVCILFGPFLDAKHEQVENCKLTSP---------FEDVFKQCLRTVIEGTRSSGSHLVFVPSLRDVHHEPVYPQPPFTFSELSREDKKRVQFVSEPCSLSINGVMFGLTSTDLLFHIGAEEIFSSSGTSDRFSRVLKHILTQRSYYPLYPPH--------------EDMAIDYENFYTYAQLP-----------------VTPDVFIVPSELRYFVKDIFGCVCVNPGRLTKG-QVGGTFGRLYLRRQPKAMDGGGRQGLSVAAQVVRI-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14181-1", "uniprot_id": "DPOA2_HUMAN", "id": "Q14181-1", "name": "DNA polymerase alpha subunit B", "aln": "------------------MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEE-GMVGELIAFCTSTHK-----VGLTSEILNSFEHEFLSKRLSK-------ARHSTC-KDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQK------YNSRSNRGEVVTSFG---LAQGVSWSGRGGAGN-ISLKVLGCPEALTGS----YKSMFQKLPDIREVLTCKIEELGSELKEHYKIEA---------FTPLLAPAQEPVTLLGQIGCDSNGKLNNKS---VILEGDREHSSGAQIPVDLSELKEYSLFPGQVVIMEGINTTGRKLVATKLYEG-------VPLPFYQPTEEDADFEQSMVLVACGPYTTSDSITYDPLLDLIAVIN-HDRPDVCILFGPFLDAKHEQVENCLLTSP---------FEDIFKQCLRTIIEGTRSSGSHLVFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFGLTSTDLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQ--------------EDMAIDYESFYVYAQLP-----------------VTPDVLIIPSELRYFVKDVLGCVCVNPGRLTKG-QVGGTFARLYLRRP--AADGAERQSPCIAVQVVRI-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VB62-1", "uniprot_id": "DPOA2_DROME", "id": "Q9VB62-1", "name": "DNA polymerase alpha subunit B", "aln": "---------------------MEEELKQQFDEMGVEPADAVLGRCAELAITYNIHDATEFVEQWMAFSLSHLQG----EDPAIENLGDFERKVLQLRKDK-------AGYKATGQKAKSYGSPSVQDTSSLATYGVMEDDPMLDDYVSESAVDSSALHTPKAKKQSDRTANLKGAALFSPASYTPQSAKRKAGLETPSNSVAGKPGDIVDTFGHPKLLAGSSWQSQMEHTVPVTQKLLHNDAPLTIAN---LGYMNDLLTDRCHNLRVRFNQTGPALVDKKLGQAGAAECIWYPQDRQVLQSAGGLHAVGMIHSEDDGPLDAHSAFMAVLDDDVEDEMDPTLTLNFSRVKSASIFPGQVVLAKGFIPRGKTFMVEEIHTE-------RKLTPATPLQIDR---ELQFVVASGPFTDSTDLFYEPLHDLLKYLK-DHRPDVLVLTGPFLDADHKMVG--ELAET---------FDTFFEKMIGGIMESIG-SHTAVLVVTSQKDAMALSVYPTPPPALRRTYPN----LYMLPDPSLVDLDGFTLGVTSTDVVDHLLSHEFAVNAG--ERMHRAINHLFHQGSFYPLYPPAD-------------EDMAYDSQLALKYAQLK-----------------QLPNVLILPSDQRHFIRLVNDCLVINPGRVAD--KKGGTFARFLVAPSVPGKAANMFN--SVACQVQRI-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38121-1", "uniprot_id": "DPOA2_YEAST", "id": "P38121-1", "name": "DNA polymerase alpha subunit B", "aln": "MSGSIDVITHFGPDADKPEIITALENLTKLHALSVEDLYIKWEQFSNQRRQTHTDLTSKNIDEFKQFLQLQMEKRANQISSSSKVNTSTKKPVIKKSLNSSPLFGLSIPKTPTLKKRKLHGPFSLSDSKQTYNVGSEAETNEKGNSSLKLEFTPGMAEDAVGDSAPLSHAKSSDAKTPGSSTFQTPTTNTPT-----TSRQNVPAGEILDSLNPENIEISSGNPNVGLLSTEEPSYNQVKVEPFYDAKKYKFRTMRQNLQEASDVLDDQIESFTKIIQNHYKLSPND-------FADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVGRRVRLDLSQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLPYPNSPVSTSQELQEFQANLEGSSLKVIVTCGPYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKTLDELFLKLFTPILKTISPHIQTVLIPSTKDAISNHAAYPQASLIRKALQLP-KRNFKCMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPGSIRTRIKPKDVSTKKETNDMESKEEKVYEHISGADLDVSYLGLTEFVGGFSPDIMIIPSELQHFARVVQNVVVINPGRFIRATGNRGSYAQITVQCPDLEDGKLTLVEGEEPVYLHNVWKRARVDLIAS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. :.:: : : : : * : : . . : .:. .. .. :. *. .: . .. : . . : . ..::: . :: *::: ::. . . . . .: : * : * . * :::. : :: .. : : :* * :. . . *: . . : ::.*.::. *:* **:* :* . * : . .: : : . .:*:.**: . .: : * ::: :: :*.* :: ***:* * : *.. :: .* : : ::: ::. .: ..** .. . :.:*. ..:: . :* :..* . .: .:. *: * :*:: * :**::* * : : * :: *:::*:**: ::* : : . : :****. *::.:: : . : .: ", "identical_positions": 54, "similar_positions": 191, "identity": "7.52%" }, { "cls_id": "homologset.agr.FB:FBgn0005771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABF5-1", "uniprot_id": "D4ABF5_RAT", "id": "D4ABF5-1", "name": "", "aln": "MSDSPAG--SNPRTP------------------------ESSGSGGS----GGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAAN----------GLGSEKDPSRSAPGAAS---AAAALKQLGDSPAED-KSSFKPYSKG-----------SGGGDSRKDGGSSSVSSTT------SSSSSSPGDKAG-FRVPSAACPPFPPHGAAVSTSSNSSSPGGSRGGSPHHSDCKSGSGGAGGGGELDKKDQEAKPSPEPAAGSRGSSGDS-AHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPP------GKPPSSSPLTGASPPS--FLQG-LCRDPYCLGG---YHSASHLGGSS----CSTCSAHDPAGPSLKASGYPLVYPG---HPLQP---AALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHT---ALPGAE-KLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRSPH-TLGLS-RYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CL69-1", "uniprot_id": "ZN703_MOUSE", "id": "P0CL69-1", "name": "Zinc finger protein 703", "aln": "MSDSPAG--SNPRTP------------------------ESSGSGGGSSSGGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAAN----------GLGSEKDPSRSAPGAAS---AAAALKQLGDSPAED-KSSFKPYSKG-----------SGGGDSRKDSGSSSVSSTT------SSSSSSPGDKAG-FRVPSAACPPFPPHGASVSTSSNSSSPGGSRGGSPHHSDCKNGGGGAG---ELDKKEQEAKPSPEPAAGSRGSGGDS-AHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPP------GKPPSSSPLTGASPPS--FLQG-LCRDPYCLGG---YHSASHLGGSS----CSTCSAHDPTGPSLKASGYPLVYPG---HPLQP---AALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHT---ALPGAE-KLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRSPH-TLGLS-RYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7S9-1", "uniprot_id": "ZN703_HUMAN", "id": "Q9H7S9-1", "name": "Zinc finger protein 703", "aln": "MSDSPAG--SNPRTP------------------------ESSGSGSG-----GGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAN-----------GLGAEKDPGRSAPGAAS---AAAALKQLGDSPAED-KSSFKPYSKG-----------SGGGDSRKDSGSSSVSSTS------SSSSSSPGDKAG-FRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGG--GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPP------GKPPSSSPLTGASPPS--FLQG-LCRDPYCLGG---YHGASHLGGSS----CSTCSAHDPAGPSLKAGGYPLVYPG---HPLQP---AALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHT---ALPGAE-KLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRNPH-TLGLS-RYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90ZE2-1", "uniprot_id": "ZN703_DANRE", "id": "Q90ZE2-1", "name": "Zinc finger protein 703", "aln": "MSELPPGFAVSPRNQ------------------------QTFKSHYITNDSSPTCLGLQVDSIAS-LPYRDPARQEKRLPIRILKMLTAHTSHILHPEYLQPLSSAPVS-IELDAKKSPLALLAQTCSQIGKPDPPPSSKLGSLSSSSHG----------DKDSRSSSSSLKSGEHQNLDDKSSFKPYSKTGSECRKEGAGINSSA-----------DKAGFRVPNGSSSSVTCTSLPPHAPSPRASSPQQTSGQSHTHRQSQSPLSQKTAHLQTTHMDSKAAGSDPGNDSSSSGSDRNGKKD--SDHNKSSLDVVQIANSSHARASVNSSSASSSSSPQPDSKTDSQPPQPSLGTGHIAPVSPFKPGHSVFPLPSSTMGYHGSIVGAYTGYPSQFVPGLDPAKS-------SLGMGVP-------GKHPSSSPLTGASPPS--FMQG-LCRDPYCLT----YPNAPHLGGSN----CSSC-VHDPS--SALKSGFPLMYPTHHLHSLHP---SSLSSSATSSLS--HPLYTYGFMLPNETLPHACNWVSVGGPCDKRFATSEELLAHLRTHT---ALPGVDGKLLSGYP---------SSVSSAASCHLHLPPPSSPGALPSSLSLRGSP-GLGLA-RYHPYGKAHLPGAPSLPMHSLPATAPYYSPYALYSQRLGSASALGYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V7W0-1", "uniprot_id": "G3V7W0_RAT", "id": "G3V7W0-1", "name": "", "aln": "MSTAPSL--SALRSSKHSGGGGGGS-------GSADPAWTSALSGNCSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGSGAGGDKDAKSGPLKLSDIGVE---DKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGG-VAAEKSGFRVPSATCQPFTPRT------GSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGAPADGVPAGLAHGRIS--CG-SGINVDVNQHSEGGPGGKALSSDCGGSSSSSS-GSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS--VMTASLCRDPYCLS----YHCASHLAGAAA--ASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHT---AFPGTD-KLLSGYPSSS---SLASAAAAAMACHMHIPTSGAPGS-PGTLALRSPHHALGLSSRYHPYSKSPLPTPG-APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMA2-1", "uniprot_id": "ZN503_MOUSE", "id": "Q7TMA2-1", "name": "Zinc finger protein 503", "aln": "MSTAPSL--SALRSSKHSGGGGGGGGGGGSGGGSADPAWTSALSGNCSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGNGAGGDKDAKSGPLKLSDIGVE---DKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGG-VAAEKSGFRVPSATCQPFTPRT------GSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGASADGVPAGLGHGRIS--CG-GGINVDVNQHSEGGPGGKALGSDCGGSSSSSS-GSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS--VMTASLCRDPYCLS----YHCASHLAGAAA--ASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHT---AFPGTD-KLLSGYPSSS---SLASAAAAAMACHMHIPTSGAPGS-PGTLALRSPHHALGLSSRYHPYSKSPLPTPG-APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F45-1", "uniprot_id": "ZN503_HUMAN", "id": "Q96F45-1", "name": "Zinc finger protein 503", "aln": "MSTAPSL--SALRSSKHSGGGGGGGGG-----GGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVE---DKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRT------GSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGG--KGTGGASAEGGPTGLAHGRIS--CG-GGINVDVNQHPDGGPGGKALGSDCGGSSGSSS-GSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS--VMTASLCRDPYCLS----YHCASHLAGAAA--ASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHT---AFPGTD-KLLSGYPSSS---SLASAAAAAMACHMHIPTSGAPGS-PGTLALRSPHHALGLSSRYHPYSKSPLPTPG-APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6UFS5-1", "uniprot_id": "ZN503_DANRE", "id": "Q6UFS5-1", "name": "Zinc finger protein 503", "aln": "MITSP----SASRNS------------------DTDLVWESSSSSSRN-----NSSAVASKPFLHSVPPSDPLRQANRLPIKILKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLSSVTSNG----------SSEKESKSGPLKLSDIGVE---DKSSFKPYSKP-ADKKDSSSGVSSG------------EKSGFRVPSATCQPFTPRT------GSPNSSTSASP----MPSDGKGE--RDEKKDSDCNKNCSSDGSA-------PTSVSHSRIS--VSCAGINVEVNQHQETTSGSKAS-------ATSDS-VSCVTSSSSASVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPQHFLPHG--------GSLVNAQLAS----SLGCSK-AGSSPLAGASPPS--IMSASLCRDPYCLS----YHCASHLAGAAG--ASCTHDSAAAAAASALKSGYPLMYPTHPLHGVHS----------SPPSFGGHPLYPYGFMLPNDPLPHVCNWVSANGPCDKRFSSSEELLNHLRTHT---AFTGTE-KLISGYPSSS---SLASAAAAAMACHMHMPPSGAPGS-PGTLALRSPHHALGLSSRYHPYSKSPLPTPG-APVPVPAATGPYYSPYALYGQRLTTASALGYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24423-1", "uniprot_id": "NOC_DROME", "id": "Q24423-1", "name": "Zinc finger protein Noc", "aln": "----------------------------------------------------------------------------MVVLEGGGGVVTIGNNQYLQPDYLAPLP------TTMDAKKSPLALLAQTCSQIGADSSAVKPLLAMDKNKTKP------------GACSSSSNSSSSSGS---AEISAAKSPSGQAKSPKSSTPISSTA-----------TSASLSNTSTGEIKLAFKP------YETNVLSHQNQNSFKSSSSLDAEPTRPSSKNSSSAQERVPSRSKSNATPTDGGKAEISAHD-----SSSSRKTVSPSGSSQRGASPIVRSGMEVLNNANGTAQHPKEMSSMAAAAAAAAAAYKAAGPYGLNPLSALCCPPGMEQHANPAFRPPFAGGFSHHHAAMLAVAANGGYPGGAPGGGPAGQPNPYISYQRIKTPAGGEAIVPVCKDPYCQGCPYSAHTQQMLMGAPCPAGCTQCEHQKYGLAMASAAGLPPAHPYSQAAAAAAAN-----------------------AAAARSAPYVCSWVVGDAYCGKRFQTSDELFSHLRTHTGNLSDPAAAAAALAQSQAQSLLGTLFPPSALRAGYPTPPLSPMSAAAAAARYHPYAKPPPGALAGGPSPFG--AAGAFNPAAAAAAAALGPYYSPYAMYGQRMGAAHQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: ..: *:*:** **. :****************** ... .. * : ... . : . :. . . . .. . .: . . : . . . . . : . . .:. *..: .* : .: * * ..: * . .: . ..*: :*:**** * *: . .* * :* . . *: *.** .. *.*** :*:**: ****** : ... :: .. : . .. :..: .. .*: *:. . .: .*******:*.**: :* ", "identical_positions": 71, "similar_positions": 110, "identity": "10.36%" }, { "cls_id": "homologset.agr.FB:FBgn0005778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32945-1", "uniprot_id": "PPQ1_YEAST", "id": "P32945-1", "name": "Serine/threonine-protein phosphatase PPQ", "aln": "MRRSPSRSNNNFAVPNCSTNSNSSQQQLTTPSDDLNSNEPNDPDDSRSLPTIKKFNNKHSINNYNTLASAGKNNNNKRASNDNLLIPGENAHKQKIYTKDENLKSLYLDIDVSVAKALSSSATAPKLINTARTSSTTTATTSNNILTSPSYRESNYSSPSSYSFSSYYSSATSASSSTSSFLKSSGLSSRVKSPSSSVKAGSFGAPSSPTSGIPNPKSSKKPIFLRRYSHDTSSNEGLDIDVAIEKLLQVGESREITKTSKKKNFPFHSWEIQLICYHAREIFLNQPTLLRLQAPIKVVGDVHGQFNDLLRILKLSGVPSDTNYLFLGDYVDRGKNSLETILLLLCYKIKYKDNFFMLRGNHESANVTKMYGFYDECKRRLSSKVWKMFVDVFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVARPTDIPESGLVTDLLWSDPDPQVTDWSENDRGVSYTFSKRNVLDFCAKFKFDLILRGHMVVEDGYEFFARKKFVTIFSAPNYCGEFHNWGAVMSVTTGMMCSFELLKPRALKNKK------------------KLYKTKV-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W2A5-1", "uniprot_id": "Q9W2A5_DROME", "id": "Q9W2A5-1", "name": "Serine/threonine-protein phosphatase", "aln": "------------------------------------------------------------MSRRSTVLSTGKES-----------------------SKEEKNRMSQLDVIIGQLKTMA--------VGNRRAGNLSEAT-----------------------------------------------------------------------------------------------------------------------------------ITYICQASRELFLSQPMLLELSAPVKICGDLHGQFKDLLRIFQQCGVPPLSNYLFLGDYVDRGHCSIETLSLLLTYKLRYPETFFLLRGNHESADLNRVYGFFDECKRRYSIKLWRSFVDCYDCMPVAAIIADRIFCVHGGLSPDLNNLDDIRRLNRPTDVPSDGLLCDLLWSDPDETTGTWASNDRGVSFTFGANIVEGFLMQHKFNLIVRAHQVVEDGYEFFADRQLVTIFSAPNYCDIFDNCGAVLVVDAKLVCHFVIIRPRPFSRPTGFESDSGSTATATNGPPPSMREKRLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. .*: *:**:. :*:*: : **: :. *::: :.. *:.. : ** * ** :**:**.** **.*.**:*: **:****:*****:: .***. :************: *:**: *** **::* :.**:********::.::***:****** * *:*: *** :: :*:**** *:*******:****:::.:*.:: ****:*..**: ******** . *:.******:**. . * .* :.**:**:*.* ********** :::**********. *.* ***: * : ::* * :::**.:.. . .: :.:: ", "identical_positions": 167, "similar_positions": 108, "identity": "29.4%" }, { "cls_id": "homologset.agr.FB:FBgn0008635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23514-1", "uniprot_id": "COPB_RAT", "id": "P23514-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFENLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNVTDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIF7-1", "uniprot_id": "COPB_MOUSE", "id": "Q9JIF7-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMTDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53618-1", "uniprot_id": "COPB_HUMAN", "id": "P53618-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HV4-1", "uniprot_id": "COPB_DANRE", "id": "Q66HV4-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVTN-DSEPPSEVSLKTDLEKGEIKAKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGKLLQEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKESELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVHTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPTHERVLQDLVMDILRVLTTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVTEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDTNEAAAADVLEFVREAIQRFDNLRPLIIEKMLEVFHAIKTVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVENELKKEAG--EVKPE-----------------EEVTAAPAPKLVTEMGTYVTQSALSTSRPSK-----KEEDRPPLRGFLMDGDFYVAASLATTLTKVALRYVALAEDKRRQNSFVAEAMLIMATVLHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRRSLSHMLAVRLEEEKLSQKKESEKRNVTVQA--DDPISFMQLTAKNEMASKEDQFQLSLLAAMGNTQRKEATDPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPASCTDAEFRQMWAEFEWENKVTVNTNITDLNDYLLHILKSTNMKCLTPEKALSG-ICGFMAANLYARSIFGEDALANVSIEKPIHLGVDAPVNGHIRIRAKSQGMALSLGDKINLSQKRTAS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45437-1", "uniprot_id": "COPB_DROME", "id": "P45437-1", "name": "Coatomer subunit beta", "aln": "--MTSQVPCYTIINSP--DLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQERALNYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSS-SNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNV-EHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWILGEYVEGSQ-ILEVIAVIQQTLGEVPMVEAEQRRLAG--DQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYS-LAPVA-----KAEKRPPLRQYLMDGDFFIGAALSATLTKLALRYAELETEARAQNRLTTQVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTLS-----ERTPEAISVFTLYCREALGKMLDAQHDEDQR-MLKEKQKATAKVQP--DDPVLFAQLSNGRDNQLGENVFESSLNQALAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYET---ALNTNVVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLKHLLKSTNMKCLTPEKALSG-QCGFMAANMYAKSIFGENALANLSIEKPVD-DPDSKVTGHIRIRAKSQGMALSLGDKISSSQKQSVQAA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41810-1", "uniprot_id": "COPB_YEAST", "id": "P41810-1", "name": "Coatomer subunit beta", "aln": "MTSLSSQPAYTLVFDPSPSMETYSSTDFQKALEKGSDEQKIDTMKSILVTMLEGNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVPKLAEDGKLRHEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLREAELLEQMVPSVLACLEYRHAYVRKYAILAVFSIFKVSEHLLPDAKEIINSFIVAETDPICKRNAFIGLAELDRENALHYLENNIADIENLDPLLQAVFVQFIRQDANRTPALKAQYIELLMELLSTTTSDEVIFETALALTVLSANPNVLVPAVNKLIDLAVKVSDNNIKLIVLDRIQDINAN--NVGALEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQLLKKELQTTVNNPDQDKAMQYRQLLIKTIRTVAVNFVEMAASVVSLLLDFIGDLNSVAASGIIAFIKEVIEKYPQLRANILENMVQTLDKVRSAKAYRGALWIMGEYAEGESEIQHCWKHIRNSVGEVPILQSEIKKLTQNQEHTEENE---------------VDATAKPTGPVILPDGTYATESAFDVKTSQKSVTDEERDSRPPIRRFVLSGDFYTAAILANTIIKLVLKFENVSKNKTVINALKAEALLILVSIVRVGQSSLVEKKIDEDSLERVMTSISILLDEVNPEEKKEEVKLLEVAFLDTTKSSFKRQIEIAKKNKHKRALKDSCKNIEPIDTPISFRQFAGVDSTNVQKDSIEEDLQLAMKGDAIHATSSSSI--SKLKKIVPLCGFSDPVYAEACITNNQFDVVLDVLLVNQTKETLKNLHVQFATLGDLKIIDTPQKTNVIPHGFHKFTVTVKVSSADTGVIFGNIIYDG-AHGEDARYVILNDVHVDIMDYIKPATADDEHFRTMWNAFEWENKISVKSQLPTLHAYLRELVKGTNMGILTPSESLGEDDCRFLSCNLYAKSSFGEDALANLCIEKDSK---TNDVIGYVRIRSKGQGLALSLGDRVALIAKKTNKLALTHV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .**:: . . * .. .:: ****. : * :::* :: :*:*: * *:* *****:* ::: :**** .:****** : **:* :******:* ::*******::**.***** **:*.**** ::*:: ***::**:***: *:**:::*:: : *:**. *:* .*: : * ******: * . *::.**.** . * ::..:. :** *:*::* : .: .*: ::::*. : :**.:: * * :*:* :* .** *..: .*.. *:* :* ****:*******: :: : .:::*.:*:**** : *::** *:* :::**. *** ::* :****: .* * :::.: :*****::*::: ::.* ::**.*:.:*::*:.* *. **:.:: *::*.*::: ** *:*::::.: ::: * :*.*:**:*** . .. * ::.::**:*::: * :: : : . * . : ***.*:** . . : :.***:* :::.***: .* *: *: *:.*:: : : * : ::.:*:: :::::*:*.: .* * :*. :*: .: * * . .:: : : : : : *. * . . * *: * *:: . :: :: .* *: . :. ***:*:. * ********** : **:*:*****:****.:**:* :::*******::: * : **.* ::...***:*::.*:*****:*: . : . *:*. :*:****** **:. * .** ** ******::*::.. *: ** .::*.*** ***.::*. * *::.*:**:* ***:****:.*** . * *::***:*.**:******:: *:: ", "identical_positions": 339, "similar_positions": 341, "identity": "34.04%" }, { "cls_id": "homologset.agr.FB:FBgn0008636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63087-1", "uniprot_id": "ALX1_RAT", "id": "Q63087-1", "name": "ALX homeobox protein 1", "aln": "-------------------MEFLSEKFALKSPPSKNSD-------------FYMGTGGALEHVMETLDNESFYG---------------------------------------KATAGKCVQAFGPLPRAEH----------------------HVRLDR----TSP-----CQD-SSVNYG---------------------------------------------ITKV----------EGQPLHTELNRAMDGCN-NLRMSPVKGMPEKS--------------------------------------------ELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAK----------SHFAATYDISVLPRTDSYPQIQNNLWAGN---TSGGSVVTSCML-PRD-ASSCMT-PYSHSPRTDSS-YTGFSNH-QNQF----------GHVPLNNFFTDSLLTGTTNGH-----AFETKPEFERRSSSIAVLRMKAKEHTANISWAM---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8B0-1", "uniprot_id": "ALX1_MOUSE", "id": "Q8C8B0-1", "name": "ALX homeobox protein 1", "aln": "-------------------MEFLSEKFALKSPPSKNSD-------------FYMGTGGALEHVMETLDNESFYG---------------------------------------KATAGKCVQAFGPLPRAEH----------------------HVRLDR----TSP-----CQD-SSVNYG---------------------------------------------ITKV----------EGQPLHTELNRAMDNCN-NLRMSPVKGMPEKS--------------------------------------------ELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAK----------SHFAATYDISVLPRTDSYPQIQNNLWAGN---ASGGSVVTSCML-PRD-ASSCMT-PYSHSPRTDSS-YTGFSNH-QNQF----------SHVPLNNFFTDSLLTGATNGH-----AFETKPEFERRSSSIAVLRMKAKEHTANISWAM---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15699-1", "uniprot_id": "ALX1_HUMAN", "id": "Q15699-1", "name": "ALX homeobox protein 1", "aln": "-------------------MEFLSEKFALKSPPSKNSD-------------FYMGAGGPLEHVMETLDNESFYS---------------------------------------KASAGKCVQAFGPLPRAEH----------------------HVRLER----TSP-----CQD-SSVNYG---------------------------------------------ITKV----------EGQPLHTELNRAMDNCN-SLRMSPVKGMQEKG--------------------------------------------ELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAK----------SHFAATYDISVLPRTDSYPQIQNNLWAGN---ASGGSVVTSCML-PRD-TSSCMT-PYSHSPRTDSS-YTGFSNH-QNQF----------SHVPLNNFFTDSLLTGATNGH-----AFETKPEFERRSSSIAVLRMKAKEHTANISWAM---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVQ7-1", "uniprot_id": "ALX1_DANRE", "id": "Q1LVQ7-1", "name": "ALX homeobox protein 1", "aln": "-------------------MEYLSDKFSLKSPAIKGSD-------------YYM------DQVMDTLDNVQYYN---------------------------------------KASP-KCVQAF-PMQSNDQ----------------------HSSMDR----SSP-----CDNQSSVTYC---------------------------------------------APKS----------EESSLH-----AMENCC-SLRVSPATSGPDKT--------------------------------------------DLDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAK----------SHFAATYDISMLPRTDSYSQISNNLWTGP---SAGSSVVSSCMI-PRG-SPPCVTSPYPHSPRAAEHGYVGFPNHQQNQFG--------VNHVSLNNFFADSLLASSANSHA----AFETKPEFERRSSSIAVLRMKAKEHTANISWAM---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZEM1-1", "uniprot_id": "D3ZEM1_RAT", "id": "D3ZEM1-1", "name": "Homeobox protein aristaless-like 4", "aln": "------MNAETCVSYCESPATAMDAYYSPVSQSREGSSPFRGFPGGDKFGTTFLSAAAKGQGFGDAKGRARYGAGQQDLAAPLES----------------------------NAGARGSFNKFQPQPPTPQPPPAP----------PAPPA--HLYLQRGACKTPPDGSLKLQEGSGGHNA---------------------------------------------ALQVPCYAKESNLGEPELPPDSEPVGMDNSYLSVKETGAKGPQDRAG------------------------------------------AEIPSPLEKTDSESSKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVR----------THFSTAYELPLLTRAENYAQIQNPSWIGN---NGAASPVPACVV-PCDPVPACMS-PHAHPPGSGASSVSDFLSVSGAGSH--------VGQTHMGSLFGAAGISPGLNGY-------EMNGEPDRKTSSIAALRMKAKEHSAAISWAT---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35137-1", "uniprot_id": "ALX4_MOUSE", "id": "O35137-1", "name": "Homeobox protein aristaless-like 4", "aln": "------MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRGFPGGDKFGTTFLSAGAKGQGFGDAKSRARYGAGQQDLAAPLES----------------------------SSGARGSFNKFQPQPPTPQPPPAP----------PAPPA--HLYLQRGACKTPPDGSLKLQEGSGGHNA---------------------------------------------ALQVPCYAKESNLGEPELPPDSEPVGMDNSYLSVKETGAKGPQDRAS------------------------------------------AEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVR----------THFSTAYELPLLTRAENYAQIQNPSWIGN---NGAASPVPACVV-PCDPVPACMS-PHAHPPGSGASSVSDFLSVSGAGSH--------VGQTHMGSLFGAAGISPGLNGY-------EMNGEPDRKTSSIAALRMKAKEHSAAISWAT---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H161-1", "uniprot_id": "ALX4_HUMAN", "id": "Q9H161-1", "name": "Homeobox protein aristaless-like 4", "aln": "------MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLES----------------------------GAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHSA---------------------------------------------ALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRAS------------------------------------------SDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVR----------THFSTAYELPLLTRAENYAQIQNPSWLGN---NGAASPVPACVV-PCDPVPACMS-PHAHPPGSGASSVTDFLSVSGAGSH--------VGQTHMGSLFGAASLSPGLNGY-------ELNGEPDRKTSSIAALRMKAKEHSAAISWAT---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LN97-1", "uniprot_id": "F1LN97_RAT", "id": "F1LN97-1", "name": "", "aln": "------MDPERCAPFA------VGPAAGPYAAARDEAP-------------GPQGTPDAAPHLRPAPPRGPRLS---------------------------------------RFPACGPLEPYLPEPAKPP----------------------AKYLQDLG----PGPVLNGGHFYKGSSE---------------------------------------------AEEKA-----SKAASFPQLPVDCRGGPRDGPSNVQGSPGPCLASLSV------------------------------------------PLSPGLPDSMELAKSKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGR----------NPFTTAYDISVLPRTDSHPQLQNSLWSS----PGSGSPGGPCLMPPEGIPSPCMS-PYSHSHGNVAG-FMGVPASP-------------AAHP---GIYSIHGFPPALGGH-----SFEPSPDGDYKSPSLVSLRMKPKEPPSLLNWTT---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70137-1", "uniprot_id": "ALX3_MOUSE", "id": "O70137-1", "name": "Homeobox protein aristaless-like 3", "aln": "------MDPERCAPFS------VGPAAGPYAAAGDEAP-------------GPQGTPDAAPHLHPAPPRGPRLS---------------------------------------RFPACGPLEPYLPEPAKPP----------------------AKYLQDLG----PGPVLNGGHFYEGSAE---------------------------------------------AEEKA-----SKAASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSV------------------------------------------PLSPGLPDSMELAKTKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQEGR----------NPFTTAYDISVLPRTDSHPQLQNSLWPS----PGSGSPGGPCLMSPEGIPSPCMS-PYSHSHGNVAG-FMGVPASP-------------AAHP---GIYSIHGFPPALGGH-----SFEPSPDGDYKSPSLVSLRMKPKEPPGLLNWTT---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95076-1", "uniprot_id": "ALX3_HUMAN", "id": "O95076-1", "name": "Homeobox protein aristaless-like 3", "aln": "------MDPEHCAPFR------VGPAPGPYVASGDEPP-------------GPQGTPAAAPHLHPAPPRGPRLT---------------------------------------RFPACGPLEPYLPEPAKPP----------------------AKYLQDLG----PGPALNGGHFYEGPAE---------------------------------------------AEEKT-----SKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHL------------------------------------------PLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGR----------NPFTAAYDISVLPRTDSHPQLQNSLWAS----PGSGSPGGPCLVSPEGIPSPCMS-PYSHPHGSVAG-FMGVPAPS-------------AAHP---GIYSIHGFPPTLGGH-----SFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PL59-1", "uniprot_id": "A0A8M9PL59_DANRE", "id": "A0A8M9PL59-1", "name": "", "aln": "------METESSLSFSS-PPNRITPDNSPGLEHNSSSF-------------FQCDDLQKSPHLALAHRHEFFMG---------------------------------------RYADGGSADFTHGVSSTTPRASPGKH---------------TKYLENINQDQKPSITEKNSSFYETNSD---------------------------------------------AGDKTL----SKPLGYPALDSECCGKLKEASNGLTGDS--------------------------------------------------------IADSIDLS-GKNKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTELTEARVQVWFQNRRAKWRKRERYGKMQEVR----------NHFAATYDISLLPRSDTY-QMQNSLWPSGAGATGAGGASSACVLGTENMPSSCMS-PYPHPHGNLPG-LMGMSASPGHHHHHHHHHHHPSHHPSINGIYSLHGFPGSLGAH-----TFEAGPESEYKPSGLVALRMKTKDPGSLLSWPT---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A6YP92-1", "uniprot_id": "ARX_RAT", "id": "A6YP92-1", "name": "Homeobox protein ARX", "aln": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQEKAMQGSPKGSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAG--AVAAAAAAA-WDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVAHPEERLSAASGPGSAPAAGGGTGTEEDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFP-----GPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35085-1", "uniprot_id": "ARX_MOUSE", "id": "O35085-1", "name": "Homeobox protein ARX", "aln": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQEKAMQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQG-AAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAG--AVAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELSGPGGVAHPEERLSAASGPGSAPAAGGGTGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAA--VATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFP-----GPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QS3-1", "uniprot_id": "ARX_HUMAN", "id": "Q96QS3-1", "name": "Homeobox protein ARX", "aln": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADPEKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQG--AAAAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVAT-----EGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFP-----GPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BQY4-1", "uniprot_id": "RHXF2_HUMAN", "id": "Q9BQY4-1", "name": "Rhox homeobox family member 2", "aln": "----------------MEPPDQCSQYMTSLLSPAVDDE-------------KELQDMNAMVLSLTEEVKEEEED---------------------------------------AQP--EPEQGTAAGEKLKS----------------------AGAQGGEEKD---GGGEEKDGGGAGVPG---------------------------------------------------------HLWEGDLEGTS--GSDGNVEDSDQSEKEPGQQYSR----------------------------------------------PQGAV-GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAV-----GQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFP-------MPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C7M4-1", "uniprot_id": "RHF2B_HUMAN", "id": "P0C7M4-1", "name": "Rhox homeobox family member 2B", "aln": "----------------MEPPDQCSQYMTSLLSPAVDDE-------------KELQDMNAMVLSLTEEVKEEEED---------------------------------------AQP--EPEQGTAAGEKLKS----------------------AGAQGGEEKD---GGGEEKDGGGAGVPG---------------------------------------------------------HLWEGNLEGTS--GSDGNVEDSDQSEKEPGQQYSR----------------------------------------------PQGAV-GGLEPGNAQQPNVHAFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAV-----GQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFP-------MPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N693-1", "uniprot_id": "ESX1_HUMAN", "id": "Q8N693-1", "name": "Homeobox protein ESX1", "aln": "---------------MESLRGYTHSDIGYRSLAVGEDI-------------EEVNDEKLTVTSLMARGGEDEEN---------------------------------------TRS--KPEYGTEAENNVGT----------------------EGSVPSDDQDREGGGGHEPEQQQEEPPL---------------------------------------------------------TKPEQQQEEPPLLELKQEQEEPPQTTVE-GPQPAE----------------------------------------------GPQTA-EGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLA-----HPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NHV9-1", "uniprot_id": "RHXF1_HUMAN", "id": "Q8NHV9-1", "name": "Rhox homeobox family member 1", "aln": "-----------------MARSLVHDTVFY-CLSVYQVK-------------ISPTPQLGAASSAEGHVGQGAPG---------------------------------------LMGNMNPEGGVNHENGMNR----------------------DGGMIPEG----GGGNQEPRQQPQPPP-----------------------------------------------------------------------------EEPAQAAME-GPQP------------------------------------------------------ENMQP----RTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRAD-------------------------PDDCVYIVVD----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M524-1", "uniprot_id": "F1M524_RAT", "id": "F1M524-1", "name": "", "aln": "---MAQRVSFDHNYYFMECEEETNAGVQARAVASTSTM-------------EASGAMAVAQAGAACRSHASRGT---------------------------------------IGYDTVYEPNVKGDPKQES----------------------ESDTEESYDDEDDDEDEGDEDDLSTSDQ---------------------------------------------------------DTSDPEQEEA---ALFVAAAAPPIAPAAAAIQIPG----------------------------------------------PHRSR--RRRHRRHRRSSPYLFTQWQVEEMENLFEETPYPDVLTRGELARTLNVPEVKVKVWFSNRRAKQRKNERRAMLRN----------------------------MPSGAEDFIFMTDVEEPC----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YCR7-1", "uniprot_id": "RHX13_MOUSE", "id": "F6YCR7-1", "name": "Homeobox protein Rhox13", "aln": "---MAHGVPFDHNYYIVECKEETNAEAQAGAMAATSTE-------------EAPGAVEVAQAAVAS-SHDSGGA---------------------------------------IGCATVKES--ESDSESES----------------------DSESES---DSSDSSDESD-DDSSTSDE---------------------------------------------------------DTSDPEEAAAPSVAAVAAAAAPPTVPAAAAIQIPG----------------------------------------------PYRYRPPRRHVRRRRRGPPFHFAQWQVEEMESLFEETQYPDLLTRGELARTLNVPEVKVKVWFTNRRAKQRKIERREMLRN----------------------------IPPGAEDFIFITDFEEPS----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W2P8-1", "uniprot_id": "Q9W2P8_DROME", "id": "Q9W2P8-1", "name": "", "aln": "-------MMTTTTSQHHQHHPIMPPAMRPAPVQESPVS--------------RPRAVYSIDQILGNQHQIKRSD---------------------------------------TPSEVLITHPHHGHPHHIHHLHS------------------SNSNGSNHLSHQQQQQHSQQQHHSQQQQ---------------------------------------------------------QQQQLQVQAKREDSPTNTDGGLDVDNDDELSSSLN-----------------------------------------------NGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGL--PEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8JJ26-1", "uniprot_id": "SEBOX_DANRE", "id": "Q8JJ26-1", "name": "Homeobox protein SEBOX", "aln": "--------------------MALFYDQSFDLGLVQKIN------------------METESDFIFNTNMLQFTD--------------------------------------------VTTKHMLSSPELDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGHVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARSMKSKKLITPVSRRSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRPPISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMN----CFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSLGDISDLIYKAAVVTNLEEC---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *: ::* * :*. * ** :.* :::** *:**: : :: ", "identical_positions": 14, "similar_positions": 17, "identity": "2.31%" }, { "cls_id": "homologset.agr.FB:FBgn0008646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04743-1", "uniprot_id": "EMX2_HUMAN", "id": "Q04743-1", "name": "Homeobox protein EMX2", "aln": "------------------------------------------MFQPAPKRCFTIESLVAKDS--------------PLPASRSEDPIRPAALSYAN-------------------SSPINPFLNGFHS-AAAAA----AGRGVYSN--------------------PDLVFAEAVSHPPNPAVPVHPVPPP------------------------------HALAAHPLPSSHSPHPLFASQ------------------------------QRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGT---------------HHINRWRIATKQASPEEIDVTSDD------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZCK7-1", "uniprot_id": "D3ZCK7_RAT", "id": "D3ZCK7-1", "name": "", "aln": "------------------------------------------MFQPAPKRCFTIESLVAKDS--------------PLPASRSEDPIRPAALSYAN-------------------SSPINPFLNGFHSAAAAAA----AGRGVYSN--------------------PDLVFAEAVSHPPNPAVPVHPVPPP------------------------------HALAAHPLPSSHSPHPLFASQ------------------------------QRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGT---------------HHINRWRIATKQASPEEIDVTSDD------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04744-1", "uniprot_id": "EMX2_MOUSE", "id": "Q04744-1", "name": "Homeobox protein EMX2", "aln": "------------------------------------------MFQPAPKRCFTIESLVAKDS--------------PLPASRSEDPIRPAALSYAN-------------------SSPINPFLNGFHSAAAAAA----AGRGVYSN--------------------PDLVFAEAVSHPPNPAVPVHPVPPP------------------------------HALAAHPLPSSHSPHPLFASQ------------------------------QRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGT---------------HHINRWRIATKQASPEEIDVTSDD------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZV90-1", "uniprot_id": "D3ZV90_RAT", "id": "D3ZV90-1", "name": "", "aln": "---------MCQAWCTPRTAAAPGHRAFPRAPLPHSSSAAATMFQPATKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEPLRPTALNYPHP------------------SAAETAFVSGFPAAAAAG-----ASRSLYGG--------------------PELVFPEAMNHP---ALTVHPA---------------------------------HQLGSSSL---QPPHSFFSAQ------------------------------HRDPLHFYPWVLR-NRFFGHRFQASEVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS---------------HHINRWRIATKQANGEDIDVTSND------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04742-1", "uniprot_id": "EMX1_MOUSE", "id": "Q04742-1", "name": "Homeobox protein EMX1", "aln": "------------------------------------------MFQPAAKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEPLRPTALNYPHP------------------SAAETAFVSGFPAAAAAG-----AGRSLYGG--------------------PELVFPEAMNHP---ALTVHPA---------------------------------HQLGSSSL---QPPHSFFSAQ------------------------------HRDPLHFYPWVLR-NRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS---------------HHINRWRIATKQANGEDIDVTSND------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04741-1", "uniprot_id": "EMX1_HUMAN", "id": "Q04741-1", "name": "Homeobox protein EMX1", "aln": "---------MCLAGCTPRKAAAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPLRPTALNYPHP------------------SAAEAAFVSGFPAAAAAG-----AGRSLYGG--------------------PELVFPEAMNHP---ALTVHPA---------------------------------HQLGASPL---QPPHSFFGAQ------------------------------HRDPLHFYPWVLR-NRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS---------------HHINRWRIATKQANGEDIDVTSND------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q804S6-1", "uniprot_id": "EMX1_DANRE", "id": "Q804S6-1", "name": "Homeobox protein EMX1", "aln": "------------------------------------------MFSATGKRCFTIESLVAKE-----------------SPITLEDPIRPTALSY---------------------SAPADSFLNGYQSP---------AGRALYPN--------------------PELVFSETVNHA---PLSMHP----------------------------------HQLGSAPL---QHPH-FFGTQ------------------------------HREPLNFYPWVLR-NRFFGHRFQGNDVSQDTLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLANSLSLSETQVKVWFQNRRTKYKRQKLEEEGPECTQKKKGN---------------HHINRWRIATKQTGSEDIDVMSDA------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFQ3-1", "uniprot_id": "Q9VFQ3_DROME", "id": "Q9VFQ3-1", "name": "", "aln": "MVTCGRQTFNMLPMAPTSPFVSSSSSVAASSTSVSASSTVSASASSKPKLAFSIDSIVGESSTRSAPLR---VSVISSPPPRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFPRFPGN-------FLFQPFR-KPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQLLQQHQQHLQQQHHQQQQHFIQQQQQLYLREREREREREREREREKSRERENQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * *:*:*:*.:. . *.* *: . :. . :. : *.. . *:*.: . . .: : : * . . : ** : . *:. :***:: : ** .. :*. .: ****:******:***:**:*** ************* .***:**************.** : * . . :.:**. *. .: : :: :: .: ", "identical_positions": 75, "similar_positions": 71, "identity": "14.02%" }, { "cls_id": "homologset.agr.FB:FBgn0008651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1XID0-1", "uniprot_id": "LBX1_RAT", "id": "Q1XID0-1", "name": "Transcription factor LBX1", "aln": "------------MTSK-EDGKA-----APGEERR-RSPLDHLPPPANSNKPLTPFSIEDILNK----PSVRRSYSLCGAAHLLAAADKHAPGGLPLAGRALLSQTSPLCALEELAS---------------------------KTFKGLEVSV-LQAAEGRDGMTI---------------------------------------------------------------------------FGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGGGGGGGGGGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPASPLTDQRASSQDCSEDEEDEEIDVDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52955-1", "uniprot_id": "LBX1_MOUSE", "id": "P52955-1", "name": "Transcription factor LBX1", "aln": "------------MTSK-EDGKA-----APGEERR-RSPLDHLPPPANSNKPLTPFSIEDILNK----PSVRRSYSLCGAAHLLAAADKHAPGGLPLAGRALLSQTSPLCALEELAS---------------------------KTFKGLEVSV-LQAAEGRDGMTI---------------------------------------------------------------------------FGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGGGGG---GGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPASPLTDQRASSQDCSEDEEDEEIDVDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52954-1", "uniprot_id": "LBX1_HUMAN", "id": "P52954-1", "name": "Transcription factor LBX1", "aln": "------------MTSK-EDGKA-----APGEERR-RSPLDHLPPPANSNKPLTPFSIEDILNK----PSVRRSYSLCGAAHLLAAADKHAQGGLPLAGRALLSQTSPLCALEELAS---------------------------KTFKGLEVSV-LQAAEGRDGMTI---------------------------------------------------------------------------FGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGG----GCGRAKSRPGSPVLPPGAPKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM39-1", "uniprot_id": "Q6ZM39_DANRE", "id": "Q6ZM39-1", "name": "", "aln": "------------MTSK-EDAKG-----ASVEDRR-RSPLDHLPPPANSNKPLTPFSIEDILNK----PSVKRSYTICGTAHLLSSGEKHPSTGHPLSNRALLTQTSPLCALEELAS---------------------------KTFKGLEVSV-LQAAEGRDGMTL---------------------------------------------------------------------------FGQRNTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKAVGNVPFEKMAKLADLEKRVNGTLGDSS------AVSPSRSN--------HEHEGTNKLHMSPSSPYTDH-TTSKECSEDE-DEEIDVDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FDX5-1", "uniprot_id": "LBX1B_DANRE", "id": "E7FDX5-1", "name": "Transcription factor LBX1b", "aln": "------------MTTI-KVVKI-----CGAMESRGLNPLDHLPPPASSNKPLTPFSITDILSK----PTVKR----FHRIHRLPASDRVRQS-ITVSRQTLITQASPLCALQELAS---------------------------KTFKGLELGV-LQAAEGKDGLKL---------------------------------------------------------------------------FGQRDSPKKRRKSRTAFTNHQLYELEKRFLHQKYLSPADRDQIAHQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESVRSTGLVPLDKLAKLADLERCAAAGATGNP-----GPQCSPRLG--------HEYKTVHKLCLSPMSSLSDH--TSQDCSEDE-EVEIDVDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q804R0-1", "uniprot_id": "LBX2_DANRE", "id": "Q804R0-1", "name": "Transcription factor LBX2", "aln": "------------MTSSSKDMKAGSVLQSSGEERR-RGPLDQLPPPANSNKPLTPFSIEDILNK----PSVKKS---VGSLCPPRVLEKVTGS--SASRNGISAPSSPLCALEELAS---------------------------KTFKGLEVSV-IQAAEGREHINA---------------------------------------------------------------------------FGQRQASKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESLKKIPPQALQKLVSMEDMED----AHGGSG------PISPSLSP-----------------RAFPQSPSSSRGQTTDEFSEED--EEIEVDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A7L0-1", "uniprot_id": "D4A7L0_RAT", "id": "D4A7L0-1", "name": "", "aln": "------------MNSG-----------------------------RQRRTP---FSIADILGR----SMVPG----APSEPRLPEAG--------------PDPASPLCALEELAS---------------------------KTFQGHSPRA-PQPSEGRAVPEAP--------------------------------------------------------------------------PGPGTGVRRRRKSRTAFTPQQVLELERRFVFQKYLAPSERDGLAARLGLANAQVVTWFQNRRAKLKRDVEEMRADLASLCGLSP-GVLCPPALPDSASSPDLQPTPSG----------------------------------PDS--------EPGLSDEE----IQVDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUN8-1", "uniprot_id": "LBX2_MOUSE", "id": "Q9WUN8-1", "name": "Transcription factor LBX2", "aln": "------------MNSV-----------------------------HQRRTP---FSIADILGP----SMVPE----APSAPQLPEAG--------------PDPASPLCALEELAS---------------------------KTFLGHSPRATPQPSEGRAAPEAP--------------------------------------------------------------------------PGPGAGVRRRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLAARLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLCGLSP-GVLCYPALPDSTSSPD--PGPSG----------------------------------PDS--------EPNLSDEE----IQVDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XYB7-1", "uniprot_id": "LBX2_HUMAN", "id": "Q6XYB7-1", "name": "Transcription factor LBX2", "aln": "------------MNSG-----------------------------REPRTPRTLLSIADILAP----RMVPR----APSAPQLPESG--------------PGPTSPLCALEELTS---------------------------KTFRGLDARA-LQPSEGRAGPDA---------------------------------------------------------------------------LGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSP-EVLCSLALPEGAPDPGLCLGPAG----------------------------------PDS--------RPHLSDEE----IQVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KH37-1", "uniprot_id": "A0A0B4KH37_DROME", "id": "A0A0B4KH37-1", "name": "", "aln": "MPQRTPSPANSDVSVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYAHMQSIGSDRDMDKDRCREKEKDKDKEELRMLKLMTLMRYSDGKLLYQQPPASYLPIPHRQNAD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :** *** * .* .**. : * : : .:*. . :::******** :*: ***:**:.****:*::** :* ***:****:*************:**:: *: . . * :.* ", "identical_positions": 58, "similar_positions": 36, "identity": "14.11%" }, { "cls_id": "homologset.agr.FB:FBgn0010014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L7T4-1", "uniprot_id": "A0ABK0L7T4_RAT", "id": "A0ABK0L7T4-1", "name": "", "aln": "MEIIRETALERTAQLLSLAWVAPSLSLFPFQSLFPALLFSLSFTFPPCCPPLSPACPSRAAQANGSTVCPAVSSLRCLCQPHCLAMGNEAS---YHSEMGT--HFDHDEIKRLGRSFKKMDLDKSGSLSVDEFMSLPELQQNPLVGRVIDIFDTDGNGEVDFREFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEFRDVVRTMEIHKKLVVFVDHGQED---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63811-1", "uniprot_id": "CANB2_MOUSE", "id": "Q63811-1", "name": "Calcineurin subunit B type 2", "aln": "-------------------------------------------------------------------------------------MGNEAS---YQTELCN--HFDQEEIRRLGKSFRKLDLDKSGSLSIEEFMRLPELQQNPLVGRVIDIFDTDGNGEVDFHEFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEFSDVVKTMEIHKKLVVFVEHGQEDLKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LZ3-1", "uniprot_id": "CANB2_HUMAN", "id": "Q96LZ3-1", "name": "Calcineurin subunit B type 2", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPAEMCS--HFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63098-1", "uniprot_id": "CANB1_HUMAN", "id": "P63098-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63100-1", "uniprot_id": "CANB1_RAT", "id": "P63100-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63810-1", "uniprot_id": "CANB1_MOUSE", "id": "Q63810-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNEAS---YPLEMCS--HFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3BEF6-1", "uniprot_id": "A0A8M3BEF6_DANRE", "id": "A0A8M3BEF6-1", "name": "", "aln": "-------------------------------------------------------------------------------------MAHKYSTMGKPLCGMTSVRFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEMKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48451-1", "uniprot_id": "CANB1_DROME", "id": "P48451-1", "name": "Calcineurin subunit B type 1", "aln": "-------------------------------------------------------------------------------------MGNETS---LPMDMCS--NFDADEIRRLGKRFRKLDLDNSGALSIDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVRGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTICFADKDEDGKISFDEFCSVVGNTDIHKKMVVDV---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25296-1", "uniprot_id": "CANB_YEAST", "id": "P25296-1", "name": "Calcineurin subunit B", "aln": "-------------------------------------------------------------------------------------MGAAPS--KIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAIETTEVAKSLTLQYDV-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * .** :**.** : * *:* *.**::. :*** :* : ***. *::::**:*..*:***:*** * * ** :*.: ****** ***:*:**:******* ***:***.** * ****:**::* *.* **::**:** .: :: *.:.: ", "identical_positions": 81, "similar_positions": 46, "identity": "30.11%" }, { "cls_id": "homologset.agr.FB:FBgn0010015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48453-1", "uniprot_id": "PP2BB_MOUSE", "id": "P48453-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform", "aln": "---------------------------MAAPEPARAAPPPPPPP------------------PPPLGADRVVKAVPFPPTHRLTSEEVFDM---DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGN------------------------EKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDV------------------------------GSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAV--QQDG-FNSLNTAHTTENHGTGNHSAQ----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20651-1", "uniprot_id": "PP2BB_RAT", "id": "P20651-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform", "aln": "---------------------------MAAPEPARAAPPPPPPP------------------PPPLGADRVVKAVPFPPTHRLTSEEVFDM---DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGN------------------------EKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDV------------------------------GSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGSSPPHRICSFEEAKGLDRINERMPPRKDAV--QQDG-FNSLNTAHTTENHGTGNHSAQ----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16298-1", "uniprot_id": "PP2BB_HUMAN", "id": "P16298-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform", "aln": "---------------------------MAAPEPARAAPPPPPPP------------------PPPPGADRVVKAVPFPPTHRLTSEEVFDL---DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGN------------------------EKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFD-------------------------------GSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAV--QQDG-FNSLNTAHATENHGTGNHTAQ----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1V9-1", "uniprot_id": "A0A8M2B1V9_DANRE", "id": "A0A8M2B1V9-1", "name": "Serine/threonine-protein phosphatase", "aln": "---------------------------MSGKDQNKQS-----------------------------TTERLVKAVPYPPTTRLTMKELYE----DGKPKVELLKSHLVKEGRLEEDVALRIINDGANILRHEKCMLEVEAPITVCGDVHGQFFDLMKLFEVGGSPHNTRYLFLGDYVDRGYFSIECVLYLWALKINHPTTLFLLRGNHECRHLTEYFTFKQECKIKYTERVYDACMEAFDCLPLAALLNQQFLCVHGGLSPEVTCLDDIRKLDRFKEPPAFGPMCDLLWSDPGEDYGS------------------------EKTSEHFCHNSVRGCSYFYSYPAVCDFLTNNNLLSVIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMSEGDDTCEG------------------------------GTPAVRKEVIRNKIRAIGKMARVFSVLREENESVLQLKGLTPTGMLPLGVLSGGRQTLQSATVEAEEAR-AIQGFNPQHKIQSFEEARGLDRINERMPPRRDTK--QPDGTANSINAANSPDKNGTNTQA------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48455-1", "uniprot_id": "PP2BC_MOUSE", "id": "P48455-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform", "aln": "---------------------------MSVRRPQFST------------------------------TERVIKAVPFPPTRRLTLKEVFE----NGKPKMDLLKNHLVKEGRVEEEVALKIINDGAAILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAALLNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDPLEDYGS------------------------EKTLEHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDEEMNV---TDE-E------------------------------GATTGRKEVIKNKIRAIGKMARVFTVLREESENVLTLKGLTPTGTLPLGVLSGGKQTIETAKQEAAEEREAIRGFTIAHRIRSFEEARGLDRINERMPPRKEASYHHDAGRMHSHSHPPHPQASRRTDHGKKAL--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48454-1", "uniprot_id": "PP2BC_HUMAN", "id": "P48454-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform", "aln": "---------------------------MSGRRFHLST------------------------------TDRVIKAVPFPPTQRLTFKEVFE----NGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGN------------------------EKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELIS---DDEAE------------------------------GSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDS--IHAGGPMKSVTS-AHSHAAHRSDQGKKAHS-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48456-1", "uniprot_id": "PP2B1_DROME", "id": "P48456-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit 1", "aln": "MSATSTRS----SVTRKSSLSKSSSSDKSAKSSSNSSKSPTAASG------------NKQKMQYTKTRERMVDDVPLPPTHKLTMSEVYDDP-KTGKPNFDALRQHFLLEGRIEEAVALRIITEGAALLREEKNMIDVEAPITVCGDIHGQFFDLVKLFEVGGPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPTTLSLLRGNHECRHLTEYFTFKQECIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIFTLDDIKTLNRFREPPAYGPMCDLLWSDPLEDFGN------------------------EKTNEFFSHNSVRGCSYFFSYSACCEFLQKNNLLSIVRAHEAQDAGYRMYRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELVAGPDDELEEELRKKIVLVPANASNNNNNNNTPS---KPASMSALRKEIIRNKIRAIGKMSRVFSILREESESVLQLKGLTPTGALPVGALSGGRDSLK----------EALQGLTASSHIHSFAEAKGLDAVNERMPPRRPLLMSASSSSITTVTRSSSSSSNNNNNNSNTSSTTTTKDISNTSSNDTATVTKTSRTTVKSATTSNVRAGFTAKKFP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23287-1", "uniprot_id": "PP2B1_YEAST", "id": "P23287-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "aln": "MSKDLN------SSRIKIIK-----PNDSYIKVDRKK---------------DLTKYELENGKVISTKDRPIASVPAITGKIPSDEEVFDSKT--GLPNHSFLREHFFHEGRLSKEQAIKILNMSTVALSKEPNLLKLKAPITICGDIHGQYYDLLKLFEVGGDPAEIDYLFLGDYVDRGAFSFECLIYLYSLKLNNLGRFWMLRGNHECKHLTSYFTFKNEMLHKYDMEVYDACCRSFNVLPLAALMNGQYFCVHGGISPELKSVEDVNKINRFREIPSRGLMCDLLWADPVENYDDARDG-----------------SEFDQSEDEFVPNSLRGCSFAFTFKASCKFLKANGLLSIIRAHEAQDAGYRMYKNNKVTGFPSLITMFSAPNYLDTYHNKAAVLKYEENVMNIRQFHMSPHPYWLPDFMDVFTWSLPFVGEKVTSMLVSILNICSEQELDPES-EPKAAEETVKARANATKETGTPSDEKASS----AILEDETRRKALRNKILAIAKVSRMFSVLREESEKVEYLKTMN-AGVLPRGALARG-----------------TEGLN--ETLSTFEKARKEDLINEKLPPSLSEVEQEKIKYYEKILKGAEKKPQL-----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14747-1", "uniprot_id": "PP2B2_YEAST", "id": "P14747-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit A2", "aln": "MSSDAIRNTEQINAAIKIIENKTERPQSSTTPIDSKASTVAAANSTATETSRDLTQYTLDDGRVVSTNRRIMNKVPAITSHVPTDEELFQPN---GIPRHEFLRDHFKREGKLSAAQAARIVTLATELFSKEPNLISVPAPITVCGDIHGQYFDLLKLFEVGGDPATTSYLFLGDYVDRGSFSFECLIYLYSLKLNFNDHFWLLRGNHECKHLTSYFTFKNEMLHKYNLDIYEKCCESFNNLPLAALMNGQYLCVHGGISPELNSLQDINNLNRFREIPSHGLMCDLLWADPIEEYDEVLDKDLTEEDIVNSKTMVPHHGKMAPSRDMFVPNSVRGCSYAFTYRAACHFLQETGLLSIIRAHEAQDAGYRMYKNTKTLGFPSLLTLFSAPNYLDTYNNKAAILKYENNVMNIRQFNMTPHPYWLPDFMDVFTWSLPFVGEKVTEMLVAILNICTEDELENDTPVIEELVGTDKKLPQAGKSEATPQPATSASPKHASILDDEHRRKALRNKILAVAKVSRMYSVLREETNKVQFLKDHN-SGVLPRGALSNG-----------------VKGLD--EALSTFERARKHDLINEKLPPSLDELKNENKKYYEKVWQKVHEHDAKNDSK-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : ** . : .*::: * *. . *:.*: **::. * :*:. .: : .* ::.: ****:***:***::**:******* * *********** **:**::**: **: : :*******:***.*****:* ** :*: * .:*: ******:* *::*:***:***: ::*:. ::** * *: * :*****:** *::.. : : : *::****: :.: * *.** ..***::*************::.:. *****:*:********.*:****:****:********: :*******:*****************.*** :*.**:::*: *:: ::*** *:.*::*::::**:*.:.* ** . :* ** *.*: * .* : :* .*: * :**::** . ", "identical_positions": 216, "similar_positions": 130, "identity": "31.95%" }, { "cls_id": "homologset.agr.FB:FBgn0010019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RRT9-1", "uniprot_id": "CP4V2_RAT", "id": "A2RRT9-1", "name": "Cytochrome P450 4V2", "aln": "-------MLWLWLGLSGQKLLLWGAASAVSVAGATVLLNILQMLVSYARKWQQMRPIPSVARAYPLVGHALFMKPNNTEFFQQIIQYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFMYKFLQPWLGLG---LLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNKLEKHVNQEAFNCFFPITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFKEGRDHKKGLKSLHTFTNNVIAERVN----ARKAEQDCIGAGRGPLPSKTK-------------------RKAFLDLLLSVTDEEGNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGR-SHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAG--YKISKGTEAVIIPYALHRDPRYFPDPEEFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWIESNQKR--EELGLAGDLILRP-NNGIWIKLKRRHEDDP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBW0-1", "uniprot_id": "CP4V2_MOUSE", "id": "Q9DBW0-1", "name": "Cytochrome P450 4V2", "aln": "-------MLWLWLGLSGQKLLLWGAASAVSLAGATILISIFPMLVSYARKWQQMRSIPSVARAYPLVGHALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLG---LLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKCLHTFTNNVIAERVK----ERKAEEDWTGAGRGPIPSKNK-------------------RKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGR-SHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGG--YKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKR--EELGLAGDLILRP-NNGIWIKLKRRHEDDP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWL3-1", "uniprot_id": "CP4V2_HUMAN", "id": "Q6ZWL3-1", "name": "Cytochrome P450 4V2", "aln": "-------MAGLWLGLVWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLG---LLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSVIAERAN----EMNANEDCRGDGRGSAPSKNK-------------------RRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGK-SDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG--YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKR--EELGLEGQLILRP-SNGIWIKLKRRNADER----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3S0-1", "uniprot_id": "CP4G1_DROME", "id": "Q9V3S0-1", "name": "Cytochrome P450 4g1", "aln": "MAVEVVQETLQQAASSSSTTVLGFSPMLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLNKYGET--MKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDG---LLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAG-KSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTE--ADFKLQADIILKL-ENGFNVSLEKRQYATVA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22443-1", "uniprot_id": "CP19A_RAT", "id": "P22443-1", "name": "Aromatase", "aln": "------MFLEMLNPMHYNVTIMVPETVPVSAMPLLLIMGLLLLIRN----CESSSSIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEF--MRVWISGEETLIISKSSSMVHVMKHSNYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTVRPFFMKALTGPGLIRMVEVCVESIKQHLDRLGDVTD---NSGYVDVVTLMRHIMLDTSNTLFLGIPLDES-----SIVKKIQGYFNAWQALLIKPNIFFKISWLYRKYERSVKDLKDEIEILVEKKRQK-VSSAEKLEDCMDFATDLIFAERR-----------------------------------GDLTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHTVVGD---RDIRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDVIDG--YPVKKGTNIILNIGRMHR-LEYFPKPNEFTLENFEKN----VPYRYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVKTLQKRCIENMPKNNDLSLHLDEDSPIVEIIFRHIFNTPFLQCLYISL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . : : : : . ** : : * : : . :: *:. : : :...: ::. : : : : :: :: .. ** * :: :: . * :: : : : :: . . . : .*: .*: : . :: : .. : : . . .: :: : . :: .: : . : . :. : ..::: : : ::: . ** :. * ::. ::: : * . :.* * . * ::: :: .* *:** * * *. * * : . * : *** :: :** :*.* :* :.* : : **. ***.* *: *:: *.:* :::.: :.: :.. :: :: *: .:. :.: *: ", "identical_positions": 48, "similar_positions": 161, "identity": "8.36%" }, { "cls_id": "homologset.agr.FB:FBgn0010038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG98-1", "uniprot_id": "GSTD2_DROME", "id": "Q9VG98-1", "name": "Glutathione S-transferase D2", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFS---IWESRAIAVYLVEKYGKDD---YLLPNDPKKRAVINQRLYFDMG---TLYESFAKYYYPLFRTGKPGSDEDLKRIETAFGFLDTFLEGQE--------------YVAG----DQLTVADIAILSTVSTFEVSEFDFSKYSNVSRWYDNAKKVTPGWDENWEGLMAMKALFDARKLAAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. . .* :* . **:. *. :*: **: ****.:**: :*:*:*:*:. **** ** ::**:** *: * .:* .:: ** *:*: . .: . :: * :. .. :. ..:. .:*.:: * :. * ** .* . * .: . ..: :::: * :.** . *: :* * :. . . ", "identical_positions": 49, "similar_positions": 78, "identity": "13.8%" }, { "cls_id": "homologset.agr.FB:FBgn0010039", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG97-1", "uniprot_id": "GSTD3_DROME", "id": "Q9VG97-1", "name": "Inactive glutathione S-transferase D3", "aln": "---------------------------------------------------------------------------------------------------------------------------------MVGKALGLEFNKKIINTLKGEQMNPDFIKINPQHSIPTLVDN---GFTIWESRAILVYLVEKYGKDD---ALYPKDIQKQAVINQRLYFDMALMYPTLAN-YYYKAFTTGQFGSEED--YKKVQETFDFLNTFLEGQDYVAGDQYTVADIAILANVSN-------FDVVGFDISKYPNVAR-----WYDHVKKITPGWEENWAGALDVKKRIEEKQNAAK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . **:.:*. ::: **: *:*:.:**: :*:*:*: .::**** ***::**:** *: *:..*: .*: ** *:*: : * :.: ::: * : ::.* : .:*:..:..:: * : . : . : * : :. ** : :.. .:* * : *.:* . : ::. . . .*:: .: . * ", "identical_positions": 46, "similar_positions": 86, "identity": "12.99%" }, { "cls_id": "homologset.agr.FB:FBgn0010040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG96-1", "uniprot_id": "GSTD4_DROME", "id": "Q9VG96-1", "name": "Glutathione S-transferase D4", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYSPRSSGSRTIIMVAKALGLELNKKQLRITEGEHLKPEFLKLNPQHTIPTLVDN---GFAIWESRAIAVYLVEKYGKDDS---LFPNDPQKRALINQRLYFDMG---TLHDSFMKYYYPFIRTGQLGNAENYKKVEAAFEFLDIFLEGQDYVAGSQLTVADIAILSSVST-------FEVVEFDISKYPNVAR-----WYANAKKITPGWDENWKGLLQMKTMYEAQKASLK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :... .: :* . **:. *. * :. *** ***:.:**: :*:*:*: .::**** ** ::**:** *: . *:.:* .:: ** *:*: . .: .. ::: * . :. . . .:*. .: .::: * : . :* . : * *: :* *: : :.. .:* * ..:* . . :: : : .. : * :* ", "identical_positions": 46, "similar_positions": 88, "identity": "12.99%" }, { "cls_id": "homologset.agr.FB:FBgn0010041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG95-1", "uniprot_id": "GSTD5_DROME", "id": "Q9VG95-1", "name": "Glutathione S-transferase D5", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYSPRGSGCRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFS---IWESRAIAVYLVEKYGKDD---TLFPKDPKKQALVNQRLYFDMGTLYDSF-AKYYYPLFHTGKPGSDED--FKKIESSFEYLNIFLEGQNYVAGDHLTVADIAILST----VSTFEIFDFDLNKYPN--------VARWYANAKKVTPGWEENWKGAVELKGVFDARQAAAKQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ... .* :* . **.: * :*: :: ****.:**: :*:*:*:*:. **** ** ::**:** *: *:..* .*: :* *:*: . : :: **: * .* : .::. : ::: * :. . .* . : * *: :* .:**: : : .. * ..:: . : :: . : . : * *. * ", "identical_positions": 48, "similar_positions": 78, "identity": "13.56%" }, { "cls_id": "homologset.agr.FB:FBgn0010042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVP-WNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG94-1", "uniprot_id": "GSTD6_DROME", "id": "Q9VG94-1", "name": "Glutathione S-transferase D6", "aln": "-----------------------------------------------------------------------------------------------------------------MDLYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDN---LFVIWETRAIVVYLVEQYGKDDS---LYPKDPQKQALINQRLYFDMG---TLYDGIAKYFFPLLRTGKPGTQENLEKLNAAFDLLNNFLDGQDYVAGNQLSVADIVILATVST--TEMVDFDLKKFPNVDRWYKNAQKVTPGWDENLARIQS------------AKKFLAENLIEKL----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. .:*. * :. . :*..:*:* :: :**: * **.:**: :*:*:*: : ***: **:::**::* *: . *:..* .*: ** *:*: . .: . :: : :. ...:. :::. .:.::: * : . :*.. : . :: :* :: ** : *: ..* *:: : ** :*::: . : * ", "identical_positions": 44, "similar_positions": 89, "identity": "12.39%" }, { "cls_id": "homologset.agr.FB:FBgn0010043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG93-1", "uniprot_id": "GSTD7_DROME", "id": "Q9VG93-1", "name": "Glutathione S-transferase D7", "aln": "--------------------------------------------------------------------------------------------------------------MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDN---GFVIWESRAIAVYLVEKYGKPD--SPLYPNDPQKRALINQRLYFDMG---TLYDALTKYFFLIFRTGKFGDQEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILAT----VSTVEWFSFDLSKFPN--------VERWLKNAPKVTPGWEQNLESLQQGKKFLQDLQAAKEKEVKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *:.. ** . : :* . **:. *: ::: *:: **** :**: :*:*:*: .: **** ** ::**:** * . *:.:* .:: ** *:*: . .: . :: :: :. . :. *:*. .:*.:: * : . :* . : . :: :* .:*.: : . : . * : . :: . : :: .: : .*.: *. : ", "identical_positions": 44, "similar_positions": 90, "identity": "12.43%" }, { "cls_id": "homologset.agr.FB:FBgn0010044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "id": "P23202-1", "name": "Transcriptional regulator URE2", "aln": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG92-1", "uniprot_id": "Q9VG92_DROME", "id": "Q9VG92-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MDFYYHPCSAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFS---IWESRAILIYLVEKYGADDS---LYPSDPQKKAVVNQRLYFDMG---TLFQSFVEAIYPQIRNNHPADPEAMQKVDSAFGHLDTFLEDQE--------------YVAGDCLT----IADIALLASVSTFEVVDFDIAQYPNVARWYENAKEVTPGWEENWDGVQLIKKLVQERNE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * .:. .* :. . **.. * :*.. **: ****.:**: :*:*:*.*:. **** ***::**:** : . *:..* .:: :* *:*: . .:: . :. * : :: .* . ::* .:* :: * ::. * ** : * .: ..: :.*: :. : **. :: :* : : * : . ", "identical_positions": 48, "similar_positions": 79, "identity": "13.56%" }, { "cls_id": "homologset.agr.FB:FBgn0010051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29994-1", "uniprot_id": "ITPR1_RAT", "id": "P29994-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "aln": "MSDKMS---SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKA--AKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYG-NVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQP--LHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV-------------------------DPDFEEECLEFQP----------SVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKG-TITQNERRSVTKLLEDLVYFVTGGTN--SGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCG--DGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK---NREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVS-TGENA-------LEAGEDEEE----------------VWLFWRDSNKEIRSKSVRELAQDAK------------EGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYD----SSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKG---------SNVMRSIHGVGELMTQVVLRG---GGFLPMTPMAAAPEGNVK-QAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVP--------------------------------GALDFEHIEEQAEGIFGGS-EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEPMDGAS---GENEHKKT------EEGTSKPLKHESTSSYNYRVVKEILIRLSKLCVQESA--SVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPL--FMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFEN-FLVDICRACNNTSDRKHADSVLEKYVTEIVMSIVTTFFSSPFSDQSTTLQ---------------TRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLK---SHNIVQKTAMNWRLSARNAARRDSVLA-ASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISID-ELENAELPQPPEAENSTEQELEPSPPLRQLEDHKRGEALRQILVNRYYGNIRPSGRRESLTSFGNGPLSPGGPSKP--GGGGGGPGSGSTSRGEMSLAEVQCHLDKEGASNLVIDLIMN-ASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKD-DEVD----RDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD-DHYQSG---------EGTQATTDKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFED----GENGEDG----AASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVD-------------------------------GDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLR-------------AQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKG--VRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRPIILTAALALILVYLFSIVGYLFFKDDFILEVDRLPNETAGPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPVEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11881-1", "uniprot_id": "ITPR1_MOUSE", "id": "P11881-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "aln": "MSDKMS---SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKA--AKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYG-NVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQP--LHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV-------------------------DPDFEEECLEFQP----------SVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKG-TITQNERRSVTKLLEDLVYFVTGGTN--SGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCG--DGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK---NREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVS-TGENA-------LEAGEDEEE----------------VWLFWRDSNKEIRSKSVRELAQDAK------------EGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYD----SSGTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKG---------SNVMRSIHGVGELMTQVVLRG---GGFLPMTPMAAAPEGNVK-QAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVP--------------------------------GALDFEHIEEQAEGIFGGS-EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEPMDGAS---GENEHKKT------EEGTSKPLKHESTSSYNYRVVKEILIRLSKLCVQESA--SVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSP---LMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFEN-FLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQ---------------TRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLK---SHNIVQKTALNWRLSARNAARRDSVLA-ASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISID-ESENAELPQAPEAENSTEQELEPSPPLRQLEDHKRGEALRQILVNRYYGNIRPSGRRESLTSFGNGPLSPGGPSKP--GGGGGGPGSSSTSRGEMSLAEVQCHLDKEGASNLVIDLIMN-ASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKD-DEVD----RDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD-DHYQSG---------EGTQATTDKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFED----GENGEDG----AASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVD-------------------------------GDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLR-------------AQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKG--VRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14643-1", "uniprot_id": "ITPR1_HUMAN", "id": "Q14643-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "aln": "MSDKMS---SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKA--AKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYG-NVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQP--LHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV-------------------------DPDFEEECLEFQP----------SVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKG-TITQNERRSVTKLLEDLVYFVTGGTN--SGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCG--DGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK---NREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSSTGENA-------LEAGEDEEE----------------VWLFWRDSNKEIRSKSVRELAQDAK------------EGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYD----SSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRG---GGFLPMTPMAAAPEGNVK-QAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVP--------------------------------GALDFEHIEEQAEGIFGGS-EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDETMDGAS---GENEHKKT------EEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESA--SVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSP---LMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFEN-FLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQ---------------TRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLK---SHSIVQKTAMNWRLSARNAARRDSVLA-ASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISID-ELDNAELPPAPDSEN-ATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKP--GGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMN-ASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKD-DEVD----RDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD-DHYQPG---------EGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFED----GENGEDG----AASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVD-------------------------------GDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLR-------------AQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKG--VRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXG4-1", "uniprot_id": "A0AB32TXG4_DANRE", "id": "A0AB32TXG4-1", "name": "Inositol 1,4,5-trisphosphate receptor", "aln": "MSDKMS---SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQFRLCPMNRYSAQKQFWKA--AKPGGNSTTDTVLLNKLHHAADLEKKQNESENRKLLGTVIQYG-NVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQP--LHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKEAILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVSEVCSTSSGSSLSCSQISTNLSLWVNPDYEEESQESRSSVADFSPFNFQLDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDKEEEKPVMLRIGTSAVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKG-TITQNERRFVTKLLEDLVFFVVDIPN--NGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSG--DGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK---NREPRFLDYLSDLCVSMNKSIPVTQELICNAVLNPANADILIETKLVLSRFEVE----SGEGP-------MESEIDEEE----------------VWLFWKNSNKEVKSKSIRELAQDAK------------EGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVMPVKYARLWSEIPSKIAIDDYD----NDGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVSTIYPINKMEKGDESKS---------SNVMKSIHGVGELMTQVVLRG---GGFLPTTPTTPPDGDVVKTQTEPEKEDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNTQTDTAPAPN--ADGPNSIPNI------------------------------PALDFENIEEQAEGIFGGS-EENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSNVEKSELWVYKRQG-DEGMDGGDGLPAESDHKKK------RDSGSDKKKTDGNGSDNYRDVKEILLRLSKLCVQEGP--SGKKSKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVRMQEIMKLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAITMQHIFMNNFQLCSEMNERVVQHFVHCIETHGRHVQYLKFLQTIVKAENKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDENSP---LMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHKDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFEN-FLVDICRVCNNTSDRKHADTTLESYVTETVMSIVTTFFSSPFSDQSTSLQVARHMYASILGKITETRQPVFVQLLQGVFRVYHCSWLLPSQKGSVESCIKVLSDVAKSRAIAIPVDLDSQVNNLFVK---SNNVVQKTILNWRLSARNASRRDSTLT-ASKDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFISKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKLIAFDDELDVAELAPPPEPEV-PAEEFDPNQPQKQLEDQKRSEALRQVLVNRYYGNFKPGGRRDSLTNFSNGPLTPVGQTKTPAGGGGGGGGGSAGSRGELSLAEVQCHLDREGASDLVIDLIMN-ATSDRIFQESILLAIALLEGGNPVIQRSFFCRLTGDNKSEKFFKVFYERMKLAQQEIKATVTVNTSDLGSKRKDEDTND----KDVQSRKKVKD-VAVITEEVREQLLEASTVTKKAFSTYRREADAD-EHLNAT---------EGPSSTAEKNQDENEMSVIITIMQPILRLMQLLCENHNRELQNFLRCQNNKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTVESLTEYCQGPCHENQNCIATHECNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEIEVEH----TDDGENGEEEHAASPRNVGHNIYILAHQLARHNKELQAMLKPGGTYGE------------------------------GDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRGTQEATGNANSVPSQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLEGGGVRGGTLEPHLSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTLFLLGAFNVGNKVIFLMSFVGNRGTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIIFKDDFILTVDRISNKT--LEQSASKMGEFLAGAVCRKEENCSTETMMDAVGVQSSALVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQMTEQRKQKQRIGLLGHPQHMNVNPQQPA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BDG0-1", "uniprot_id": "A0A8M2BDG0_DANRE", "id": "A0A8M2BDG0-1", "name": "Inositol 1,4,5-trisphosphate receptor", "aln": "MVDKLS---SFLHIGDVCSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKA--AKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYG-NVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNAGQP--LHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV-------------------------NPDYEEECLESRS----------SMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKG-TITQNERRSVTKLLEDLVYFVVDIPS--SAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSG--DGPMLRLEELADQRHAPFRHICRLCYRVLRYSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK---NREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAG-TVLGEGA-------EEEEEDEEE----------------VWLFWKDSGGEVKSKSIRELAQDAK------------DGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYD----NDGTSSDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHISTPFHIKLDR--EPGKG---------SNVMRSIHGVGELMTQVVLRG---GGFLPASSHNPPDRDEVKAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDESNSQSEPSLSPE----SPASVQ--------------------------------GALDFEHIEEQAEGIFGGSSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRQGSDSGLDAGEVTPEAHHKGVI------NSSRSNKPKVESTSSSNYRVVKEILLRLSKLCVLEGI--SGKKNKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVQMQEIMTLAHQFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIVKAENKFIKKCQDIVMAELVTAGEDVLVFYNDRASFQSLVQMMRLERERLDESSA---LRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIYTSNHMWKLFDD-FLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSLQ---------------TRQPVFVQLLQGVFRVYHCNWLLPGQKGNVEACIKVLSDVAKGRAIAIPVDLDCQVNNLFMK---SNNIVQKTALSWRLSVRNATRRDSVLT-TSRDYRNIIERLQDIVSALEERLRPLVQAELSVLVDVLHRPELLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKLLGYDDEMDVTEV-------------VDISLPPKQQEDRQRGEALRQLLVNRYYG-FRSGGRRESLTSFGNSTLTPVGPIKS---------QPGGLSRAEMSLMEVQCHLDREGASDLVIDLIMN-TTSDRVFHESILLAIALLEGGNTIIQHSFFKRLTEDKNSEKFFRVFYDRMKVAQVEIKATVTVNTSDLGNKRRDDNTPD----KDTPQRRRGKDSGVVVTDDAREQLLEASAATKKAFGSYRRDADPE-ETFGTA---------DGDKGGGDKGTEQGEMSPVILIMQPILRFLQLLCENHNRDLQNFLRCQNNKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINQHNVALINQTVESLTEYCQGPCHDNQNCIATHESNGIDIIIALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVMKMAYQQGEAEFEDEE--QENGEDH----AASPRNVGHNIYILAHQLSRHNKELQILLKPGGEDQ----------------------------------ALEYYTKHTSQIEIVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKINDFFLHADDLFNEMRWQKKLR-------------AQPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFYPLDG--VSESQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLTLLGAFNVCNKIVFMLSFVGNRGSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGT--LEEGVTLP-----AGFCDARNGS----------CLSDDVDEDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRLGLLGNPAHLNINPQQPA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29995-1", "uniprot_id": "ITPR2_RAT", "id": "P29995-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "aln": "MSDKMS---SFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLTNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNH--TEAALLKKLQHAAELEQKQNESENRKLLGEIVKYS-KVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQP--LHASNVELLDNPGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTCDDYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAEL-------------------------NPDYRDAQN--EGK---------TVRDGELPTSKKKHQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKLENG-SITQNERRFVTKLLEDLIFFVADVTN--NGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAG-EGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRR---NREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENP----MESSI-------LPDDIDDEE----------------VWLYWIDSNKEPHGKAIRHLAQEAR------------EGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYD---SITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSN----------NVMRTIHGVGEMMTQMVLSR--GSIFPVSWPDAQPSVHPSKQASPGEQEDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGENDGNGDPSASGTPETLLPSALVP----------------------------------DIDEIAAQAETMFAG-RKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDMGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNK------KCRNQHQRLLKNMGAHSVVLDLLQIPYEKT-DEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGP---LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFEN-FLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQ---------------THQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRALAEVAKNRGIAIPVDLDSQVNTLFMK--NHSSTVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFSPMMQAEFSVLVDVLYSPELLFPEG--SDARIRCGAFMSKLINHTKKLME-KEEKLCIKILQTLREMLEKKDSFMEE-----------------------------------------SSTLRKILLNRYFKGDHSVGVNGPLSGAYAKTAQVGGGFTG-----------QDADKTGISMSDIQCLLDKEGASELVIDVIVN-TKNDRIFSEGILLGIALLEGGNTQTQNSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKREEDSDL----MALGPRMRVRDSSLHLKEGMKGQLTEASSATSKAYCVYRREMDPDIDTMCPG---------QEAGSAEEKSAEEVTMSPAITIMRPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILSDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPKELVDVMKNAYNQG-LECNHG-------DEEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDP------------------------------EEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIR-------------NNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLS-PLFSALLWVAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNDGVPTMTLTSM-LGTCPKEN-CSPTIPSSNAAGEGGE-DGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEKILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHENHHMPPH-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z329-1", "uniprot_id": "ITPR2_MOUSE", "id": "Q9Z329-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "aln": "MSDKMS---SFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNH--TEAALLKKLQHAAELEQKQNESENRKLLGEIVKYS-NVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQP--LHASNVELLDNPGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTCDDYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAEL-------------------------NPDYRDAQN--EGK---------NVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKLENG-SITQNERRFVTKLLEDLIFFVADVTN--NGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAG-EGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRR---NREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENP----MESSI-------LPDDIDDEE----------------VWLYWIDSNKEPHGKAIRHLAQEAR------------EGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYD---SITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSN----------NVMRTIHGVGEMMTQMVLSR--GSIFPVSVPDAQPIVHPSKQASPGEQEDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGDNNDNGDPSASGTPDTLLPSALVP----------------------------------DIDEIAAQAETMFAG-RKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDVGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNK------KCRNQHQRLLKNMGAHSVVLDLLQIPYEKT-DEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGP---LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFEN-FLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQ---------------THQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRALAEVAKNRGIAIPVDLDSQVNTLFMK--NHSSTVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFSPMMQAEFSVLVDVLYSPELLFPEG--SDARIRCGAFMSKLINHTKKLME-KEEKLCIKILQTLREMLEKKDSFMEE-----------------------------------------GSTLRRILLNRYFKGDHSISVNGPLSGAYAKTAQVGGSFSG-----------QDSDKKGISMSDIQCLLDKEGASELVIDVIVN-TKNDRIFSEGILLGIALLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKREEDSDV----MALGPRMRVRDSSLHLREGMKGQLTEASSATSKAYCVYRREMDPEIDTMCPG---------QEAGSAEEKSAEEVTMSPAITIMRPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQG-LECDHG-------DEEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDP------------------------------EEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIR-------------NNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLS-PMFSVLLWVAVAICTSMLFFFSKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSM-METCQKEN-CSPTIPSSNTAGEEGE-DGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPPH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14571-1", "uniprot_id": "ITPR2_HUMAN", "id": "Q14571-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "aln": "MTEKMS---SFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNH--TEAALLKKLQHAAELEQKQNESENKKLLGEIVKYS-NVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQP--LHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVVRLFHAEQEKFLTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAEL-------------------------NPDYRDAQN--EGK---------NVRDGVPPTSKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFAIVSVPLSEVRDLDFANDANKVLATTVKKLENG-TITQNERRFVTKLLEDLIFFVADVPN--NGQEVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAG-EGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRR---NREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNP----MESSI-------LSDDIDDEE----------------VWLYWIDSNKEPHGKAIRHLAQEAK------------EGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYD---SITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGGN----------NVMRTIHGVGEMMTQMVLSR--GSIFPMSVPDVPPSIHPSKQGSPTEHEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLLPSAIVP----------------------------------DIDEIAAQAETMFAG-RKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSNYENGEIGESQVKGGEEPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNK------KCRNQHQRLLKNMGAHSVVLDLLQIPYEKN-DEKMNEVMNLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGP---LAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFEN-FLVDMARVCNTTTDRKHADIFLEKCVTESIMNIVSGFFNSPFSDNSTSLQ---------------THQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRTLAEVAKNRGIAIPVDLDSQVNTLFMK--SHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEG--SDARIRCGAFMSKLINHTKKLME-KEEKLCIKILQTLREMLEKKDSFVEE-----------------------------------------GNTLRKILLNRYFKGDYSIGVNGHLSGAYSKTAQVGGSFSG-----------QDSDKMGISMSDIQCLLDKEGASELVIDVIVN-TKNDRIFSEGIFLGIALLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNEL----MTSGPRMRVRDSTLHLKEGMKGQLTEASSATSKAYCVYRREMDPEIDIMCTG---------PEAGNTEEKSAEEVTMSPAIAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALVNQNLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQG-LECDHG-------DDEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDP------------------------------DEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIR-------------NNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLS-PLFSVLLWIAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGSHQVPTMTLTTM-MEACAKEN-CSPTIPASNTADEEYE-DGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRSLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPPH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQQ3-1", "uniprot_id": "A0A8M9PQQ3_DANRE", "id": "A0A8M9PQQ3-1", "name": "Inositol 1,4,5-trisphosphate receptor", "aln": "MSEHRS---SFLHIGDIVSLYAEGTVNGFISTLGLVDDRCVVQPETGDLTNPPKKFRDCLFKVCPMNRYSAQRQFWKAKQGKHGNN--TQADLFKKLQHAAELEQKQNDSENKKLLGEVVKYS-RVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDPSGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNAGQP--LHASNIELLDNRGCKEVNALNCNTSWKVTLFMKFSEYRDDILKGGDVVRLFHAEQEKFLTCDEYKKQQYVFLRTTLRQSATSATSSKALWEVEVVHYDPCRGGAGQWNSLFRFKHLATGHYLAAEV-------------------------NPDFKDRTDSITTK---------NETNTESLYSKKKWQA-DKIPYTLVAVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRNLCTNTWVTSTNIPIDVEEERPVMLKIGTCHMKEDKEAFSINSVPLSEVRDLDFANDANKVLESFVRILGISNYAAANERRFTIKLLEDLIFFVGDVPN--NGQDVLSVVISNPNRERQKLMREQNILAQIFGILKAPFSEIK--DSPMPKLEDVGEQRNSAFKYMLQLCYRTLRHSQQDYRKNQEYIAKNFSIMQAQIGYEILAEDTITALLHNNRKLLEKHITAREIETFVKLLRR---NREPRFLDYLSDLCVSNKTAIPVTQELICKFMLNPTNADILIQTKLI-QHTETS----LESSL-------LHDDVEDEE----------------VWLYWIDHHKEPHGKSIRHLAQDAK------------DGQKLDTDIITYYRCQLNLFAKMCLDRQYLAINQISIPLPVDLILRCMFDDCLPYNLRASFCRLMLHMHVDRDPQEAVVPVRYARLWTEIPSKISVNEYDY--EFRDTSREEMKRKFAPTMHFVDEYLKDVVSQPDPFGDREKNELTLEVVHLARNLVYFGFYSFNELLSLTRTLLAILDIVQP-TYTFMSKLNKGPEGGN----------NVMRTIHGVGEMVTQMVLSR--GLMMPHCLPDAQPIHG--KQICLPDNENVMVMDTKLRIIEILQFILNVRLDYRITYLLSIYKKEFGDHTLDASASVAEVP-----VMAEP----------------------------------NIEDIAEKAENMFSGSAKERSPVDLDDEGGQTFLRVLIHLIMQDYPPLVSGSLQLIFKHFSQRSEVLQAFKQVQLLVSEEDVENYKKIKASLDQLRLTVEKSELWVEKSGGYGSEDLTENQNK--EQNSEEAGILSPVQDGNSKPQIDSNKANNYKIVKEILLSLSKLCSPAK------KTRVQQQRLLKNMGAHTVVLDLLQIPYEKG-DEKMDEIMTLAHTFLQYFCKDNVQNQALLHKHLNLFLTPGLLEAKTMCYIFMNNYHLCNEISDRVVHHFVHCIETHGRHVQYLRFLQTIVKADGKYVKECQCKVMNELVNGGEDVLVFYNDRASFPALQSMMCSG---LDETGA---LMYHITLVELLAACTEGKNVDTELKCNSLLPLDDIVNVVTYDGCTPEVKIAYVNFVNHCYVDTEVEMKEIYTSDHIWNLFDS-FLVDMATVSIGPTDRKNADTSLEKYVTDTIMAIVKGFFGSQFSVSNSKLQ---------------AHQATFIKLLQSACRLYNCTWLNSLQKTNIEGCIKTLADVAKSRAIPIPVDLDGQVNALSLK--THTSMVQRAVKDWRLSARGRPR-KEPFG--AHDYK-IIEKLQGVVSYLEEQFNPRVQAEFSVLVDVLHSPEMLFPES--AQLRTEDGAFLSKLIKHTKKLME-KEEKLCIKILQTLREMLDRREMFDEK-----------------------------------------GNALRKSLLAHYFG-----NHTKALEYSSSNSSSSGGGSPG-----------QDSDKPGTSLADIQCVLDNVGASELVVDLIVS-TKNDRIFEESILLGIALLRGGNTQIQNSFHNQLHKQKKSEKFFRVFYERMEQAQKEIRSSVSVNMFELSCRKREEESEG----SGIR-HKKVRDS-LHLREEMRGQLKDASSVTSKAYSTFRREWDPDIEAVG------------TTGDATEEVVEEIQMSQAITIMKPILRFLQLLCENHNRDLQNFLRDQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVYLVIQTLETITEYCQGPCHENQSCIARHESNGIDIIIALIVNPIDPLGKNRLDLVLELKNNASKLLLAIMESRQDSENAEKILYKMRPNELVDVIKEAYVQGEEECEID-------DET--LDLIRSKDVGHNIYILAHQLAKHRKNLQQSLKPGPDPT-----------------------------IDGEAALTYYTNHTAQIEIVRHDRTMEQIVFPVPNICEYLTEESKVRVFTTTERDDQGSKVNDFFQQFDDLYNEMRWQKKIR-------------NNAPLFWVSKHISLWGSISFNMAVLINLAVALFYPFGDDGDEGVLP-PFLSVLLWGAVVVSTFTLFILPPRGGILAFLVTVIFRSIYTLGLGPTLLLLGAANLLNKIVFLVSFVGNQGTFTRGYKAVIMDVFFLLHVSYVIVCMLGLFVHEFFYSILLFDLVRREETLLNVMRSVTKNGRSIFLTAVLAIILVYLFSIVGFLFFKDDFLMEVDHLPLKRPNVNGKSMS-----------CVSAD-CAESMFSRNHVEEEDE-DGSERVCDTLLMCIITVLNHGLRNGGGIADVLRKLSKEEPMFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIKEKNLDWFPRMRAMSLVSSEGESEQNEIRSLQERLDTTVSLVAQLSSQLSELKEQMTEQRKNKQRLGFLGP--PQMNHQIAPAL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63269-1", "uniprot_id": "ITPR3_RAT", "id": "Q63269-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "aln": "-MNEMS---SFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYG-SVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQP--LHASNYELSDNVGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYRGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEE-------------------------NPSYKGDVS---DP---------KAAGPGAQSRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEG-FISQNDRRFVIQLLEDLVFFVSDVPN--NGQNVLDIMVTKPNRERQKLMRDENILKQIFGILKAPFRDKGG-EGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK---NREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELR-PVKEMA----QSHEY-------LSIEYSEEE----------------VWLTWTDRNNEHHEKSVRQLAQEAR------------AGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISKQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYD---SNLNASRDDKKNKFASTMEFVEDYLNNVVGEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQA--PAAVLQAYEEPG-GK----------NVRRSIQGVGHMMSTMVLSRKQSVFGASSLPTGVGVPEQLDRSKFEDNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSSTANM----------------------------------NLDRIGEQAEAMFGV-GKTSSMLEVDDEGGRMFLRVLLHLTMHDYPPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSVK----GEEGEAGASKDKKE----RPSDEEGFLQPHGEKSSENYQIVKGILERLNKMCGVGE------QMRKKQQRLLKNMDAHKVMLDLLQIPYDKN-DNKMMEILRYTHQFLQKFCAGNPGNQALLHKHLQLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHCWPTHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSP---LMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFEN-FTLDMALVCN-KREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQ---------------THQTIVVQLLQSTTRLLECPWLQQQHKGSVEACVRTLAMVAKSRAILLPMDLDAHMSALLSSGGSCSAAAQRSAANYKTATRTFPRVIPTAN--QWDYKNIIEKLQDIITALEERLKPLVQAELSVLVDMLHWPELLFLEGSEAYQRCESGGFLSKLIRHTKGLME-SEEKLCVKVLRTLQQMLQKKSKYGDR-----------------------------------------GNQLRKMLLQNYLQ-------NRKSGPRGELTDPTG----------------SGVDQDWSAIAATQCRLDKEGATKLVCDLITS-TKNEKIFQESIGLAIRLLDGGNTEIQKSFYNLMTSDKKSERFFKVLHDRMKRAQQETKSTVAVNMSDLGSQPREDREP-------------------------------ADPTTKGRVSSFSMP-SSSRYSLGPG---------LHRGHDVSERAQNNEMGTSVLIMRPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIKKAYLQE-EEREN--------------SEVSPREVGHNIYILALQLSRHNKQLQHLLKPVKRIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPAICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLR-------------SMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYVEGASTGVLGSPLISLLFWILICFSIAALFTK--HYSVRPLIVALVLRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASTLGMPHGAATFMGTCSGDKMD-CVSEVSVPEILEEDEELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTAQLNELKEQMTEQRKRRQRLGFVDVQNCMSR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70227-1", "uniprot_id": "ITPR3_MOUSE", "id": "P70227-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "aln": "-MNEMS---SFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYG-SVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQP--LHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYRGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEE-------------------------NPSYKGDVS---DP---------KAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEG-FISQNDRRFVIQLLEDLVFFVSDVPN--NGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGG-EGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK---NREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELR-PVKEMA----QSHEY-------LSIEYSEEE----------------VWLTWTDRNNEHHEKSVRQLAQEAR------------AGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISKQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYD---SNLNASRDDKKNKFASTMEFVEDYLNNVVSEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQA--PAAMLQAYEEPG-GK----------NVRRSIQGVGHMMSTMVLSRKQSVFGASSLPAGVGVPEQLDRSKFEDNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSSTATM----------------------------------NLDRIGEQAEAMFGV-GKTSSMLEVDDEGGRMFLRVLLHLTMHDYPSLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSVK----GEEVEAGATKDKKE----RPSDEEGFLQPHGEKSSENYQIVKGILERLNKMCGVGE------QMRKKQQRLLKNMDAHKVMLDLLQIPYDKS-DNKMLEILRYTHQFLQKFCAGNPGNQALLHKHLQLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSP---LMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVTVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFEN-FTLDMALVCN-KREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQ---------------THQTIVVQLLQSTTRLLECPWLQQQHKGSVEACVRTLAMVAKSRAILLPMDLDAHMSALLSSGGSCSAAAQRSAANYKTATRTFPRVIPTAN--QWDYKNIIEKLQDIIMALEERLKPLVQAELSVLVDMLHWPELLFPEGSEAYQRCESGGFLSKLIRHTKGLME-SEEKLCVKVLRTLQQMLLKKSKFGDR-----------------------------------------GNQLRKMLLQNYLQ-------NRKSGARGELTDPTG----------------SGLDQDWSAIAATQCRLDKEGATKLVCDLITS-TKNEKIFQESIGLAIRLLDGGNTEIQKSFYNLMTSDKKSERFFKVLHDRMKRAQQETKSTVAVNMSDLGSQPREDREP-------------------------------ADPATKGRVSSFSMP-SSSRYLLGLG---------LHRGHDMSERAQNNEMGTSVLIMRPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIKKAYLQE-EEREN--------------SEVSPREVGHNIYILALQLSRHNKQLQHLLKPVRRIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPAICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLR-------------SMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYVEGASTGVLGSPLISLLFWILICFSIAALFTK--RYSVRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASPLGMPHGAATFMGTCSGDKMD-CVSEVSVPEILEEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTSQLNELKEQMTEQRKRRQRLGFVDVQNCMSR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14573-1", "uniprot_id": "ITPR3_HUMAN", "id": "Q14573-1", "name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "aln": "-MSEMS---SFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYG-SVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQP--LHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYKGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEE-------------------------NPSYKGDAS---DP---------KAAGMGAQGRTGRRNAGEKIKYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEG-FISQNDRRFVIQLLEDLVFFVSDVPN--NGQNVLDIMVTKPNRERQKLMREQNILKQVFGILKAPFREKGG-EGPLVRLEELSDQKNAPYQHMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK---NREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELR-PVKEMA----QSHEY-------LSIEYSEEE----------------VWLTWTDKNNEHHEKSVRQLAQEAR------------AGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYD---SNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVPFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQG--PPAMLQAYEDPG-GK----------NVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSTTANM----------------------------------NLDRIGEQAEAMFGV-GKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGK----GEEVEAGAAKDKKE----RPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGE------QMRKKQQRLLKNMDAHKVMLDLLQIPYDKG-DAKMMEILRYTHQFLQKFCAGNPGNQALLHKHLHLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSP---LMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFEN-FTLDMARVCS-KREKRVADPTLEKYVLSVVLDTINAFFSSPFSENSTSLQ---------------THQTIVVQLLQSTTRLLECPWLQQQHKGSVEACIRTLAMVAKGRAILLPMDLDAHISSMLSSGASCAAAAQRNASSYKATTRAFPRVTPTAN--QWDYKNIIEKLQDIITALEERLKPLVQAELSVLVDVLHWPELLFLEGSEAYQRCESGGFLSKLIQHTKDLME-SEEKLCIKVLRTLQQMLLKKTKYGDR-----------------------------------------GNQLRKMLLQNYLQ-------NRKSTSRGDLPDPIG----------------TGLDPDWSAIAATQCRLDKEGATKLVCDLITS-TKNEKIFQESIGLAIHLLDGGNTEIQKSFHNLMMSDKKSERFFKVLHDRMKRAQQETKSTVAVNMNDLGSQPHEDREP-------------------------------VDPTTKGRVASFSIPGSSSRYSLGPS---------LRRGHEVSERVQSSEMGTSVLIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIKKAYLQE-EEREN--------------SEVSPREVGHNIYILALQLSRHNKQLQHLLKPVKRIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPGICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLR-------------SMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYMEGASTGVLDSPLISLLFWILICFSIAALFTK--RYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPNNHSTASPLGMPHGAAAFVDTCSGDKMD-CVSGLSVPEVLEEDRELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELKEQMTEQRKRRQRLGFVDVQNCISR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z266-1", "uniprot_id": "A0A8M6Z266_DANRE", "id": "A0A8M6Z266-1", "name": "Inositol 1,4,5-trisphosphate receptor", "aln": "MSDSAS---SFLHIGDIVSLYAEGTVNGFISTLGLVDDRCVVEPASGDLENPPKKFRDCLFKVYPMNRYSAQKQFWKAKQAKHEKDKIGDMVLLQKLQHAANLEQKQNDAENKKVHGDVVKYG-SVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVVVGDKVILNPVNAGQP--LHASSYELPDHSGCKEINSVNSNTSWKISLFMMFSDHKDEVLKGGDVVRLFHAEQEKFLTCDEYKSKLHVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGNYLAAEE-------------------------NPGYKENSN---D--------------IEVDSSRIKRSLGERIKYKLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRFRHLCTNTWIQSTNIPIDIDEERPIRLMLGTCPTKEDKEAFAIVSVPVMEIRDLDFANDASLMLSTVVEKFKYG-FLSPNDRRYAIKLLEDVVFFVVDQLN--NGQPALEVSMNKPNRERQKLMREQNILKQIFGIIKAPFKERGD-DPPLLTLEELSDQKYLLYQYMLRLCYRVLRHSQEDYRKNQEYIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK---NREPRFLDYLSDLCVSNNVAIPVTQELICKCVLNAKNQDILMKTERR-AAKESQ----HTSEY-------LEEFGDEDE----------------VWLIWSEKENENHEKSIRQLAQEAR------------QGNVHDENVLTYYRYQLKLFARMCFDRQYLAIDVISKQLDIELISLCMMDETLPFDLRASFCRLMLHAHVDRDPQELVTPIKFARLWTEIPTSISIKDYD---SHLDYSRDNKKNKFANTMAFMEEYLNNVLIDDLPFANEEKNKLTYEVVSLARHLIYFGFYSFFELLRLTRTLLGIIDCTPS--NASINPLFNDDGSGK----------NVRRSIHGMGQMMSTMVLNRKPSLFSAP----GRTGDSQVGSKDSIDTQDITVMDTKLKILEILQFILSVRLDYRLSFLLSVFKKEFVDVYPMEDADAT----HHTEHEASI----------------------------------NLQHIGEQAEAMFGI-GKGNSILEVDDEGGRMFLRVLIHLIMHDYPPLVSGALQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKHIKRDLDLLRTMVEKSELWVIKKSSSG----GDGKKD--KKDKKEPEAVSPEEEADSKKQTTEKSNESYQNVKEILERLNKMCSSG--------VFKKQQRLLKNMGAHKVMLDLLQISYDRN-DTKMLEIIKYTHLFLQKFCTGNLENQALLHKHLNLFLTPRLLEAETMQQIFSNNFQLCSEISESVLHHFIHCLATQGRHIQYLNFLHTIIKAEGKYVKKCQDMIMTELTSAGDDVVVLYTDDTSFNTMVELMTQSREGVKDDSP---LRYHISLVELLAACAEGKNVYTEIKCTSLLPLEEMVKVITHEDCITEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFEN-FTVDMARVCS-NREKRMSDPVLEKYVIQVVLDTVTAFFSSPFSENSTSTE---------------AHHTTVKQLLQSTMRLLDCPWLQPQQKVQVESCIRTLAVTTKSRSIPLPVELEAHVNMMLS--HSNSLTLSRSSHSNKSMSR-LTRPAAPTN--PWDYKNIIEKLQDIINTLEERVMPLVNAELSVLVDVLHQPELLFLEGTDARSRCESGGFISKLIQHTKALMN-SDEKLCIKVLRTLQEMLIRELDFDEK-----------------------------------------GFALRKVLLQNYLY-------NNKKNIKAELVEHAGG---------------AEGERDWLTVAALQCRLDKEGGTKLFTDLITS-TKNEKIFQESIQLAICLLEGGNTEIQNSFYKLMMGDNKSEKFFKVLNDRMKNAQLDIKSTVSVNVGEMSNKAKDDKD-----------------------------------LETGGVSSFGQP-----------------------EPQPEQQEVETEMGPSVTIMKPILRFLQLLCENHNQDLQNFLRIQNNKTNYNLVSETLQFLDIMCGSTTGGLGLLGLYINENNVELITQTLETLTEYCQGPCQENQTCIVSHECNGIDIITALILNDISPLCRYRMELVLQLKDNASKLLLALMESRHDSENAERILFNLRPRELVELIKKAYLQE-GECKE--------------GEVSPREVGHNIYILALQLARHNKVLLTLLKPVKKIKEEEEESISSMLNLNKQQE-----------EEKEDPLEHYDRQTAQIEIVREDRSMEQIVFPVHPICEFLTEESKFRVFTTTEQDEQGSKVTNFFEQTSFLHNEMEWQKKLR-------------SMPVLYWFSRRMSLWGTISFNLAVFINLIIALFYPHDSGHS-GSIDSSLLLMGFWCFAGLAVLGLLFK--RYGFQSLTVAITLRCIYHFGIGPTLLLLGALNLINKIVYLVSFVGNNGTFIMGYKAMVMDVEFLYHVAYVLTSSLGLFVHEFFYSILLFDLIYREETLFNVIKSVTRNGRSILLTAVLAIILVYLFSIVGFLFLRNDFIMEVDHLAS--------PAPGDTESFMSSCSSDGID-CTEETGLLAPAEEDE--DNTERACDTLLMCIITVLNHGLRNGGGVGDVLRKPSKNEPLFPARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKLEHNIWNYLYFIVLIREKNKTDYTGPESYVALMIKNKNLDWFPRMQAMSLVVTDGDGEQNEMRNLQDRLSSTMKVVTQLTSQLTELKEQMTEQRKRRQRMGFVDVQSGSNPGMPVPPSPAGGNQVYKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29993-1", "uniprot_id": "ITPR_DROME", "id": "P29993-1", "name": "Inositol 1,4,5-trisphosphate receptor", "aln": "MGDNIIGSASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKA--AKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYKKQYHVFLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVS--------------------AGAMSATSASGHDLHLG--DCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNG-SISINERRALISLLQDIVYFIAGMENEQNKTKALEFTIKNPIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQQDYRKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNSEDVCLATLAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTPSTGDKYEIHLKWTGQPTSRSMADLASCDGGELEAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYELRASFCRLMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTIAFVENYLCNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTSSGEFASTDIDSVEEETN---AEAEGGVLRSIGDINTVMTSLALGS-----VGQAIAAPTISLQQRKSVSQLMKEYPLVMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQSQQQEPQTPGSSNETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDLDGQGGRTFLRVLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYKAKATD--------ELGATDAGGD------AVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGILEAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVAYLQFLQTVVRAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTEVEMKEIYASGHMWSLFEKSFLVDINQLITNPAAAS--NKTLQAYVLNGVTNLLGSFFASPFSDQSAIVQ---------------SRQLIFVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVATMSSK----TAMLTRQTTKWLLASKQPKYEAQQAASLMRWDRSIIEGLQDIVSLLEDQLKPVVEAELSLLVDILYRSELLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDVNYGEK-----------------------------------------GDALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQNHLVTHG---PGAKYLQRAGKTLHEMQNHLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQKGMFQKFLSDDLNQAFFKVFFEKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGLKSNGVVITEELKRELHNAGLATARAYGNARNIHSGEESSAISVNSPLEDILAEKLEKHKDSRDQRNQLSNKVLVMQPILRFLQLLCENHNPDMQNLLRNQNNKTNNNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVALINQTLEALTEYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMNPKQLVEVACKAYHQEELIDEQDDGDEPDAGSDDDDATVSPREVGHNIYILCHQLAQHNKELAGLLKASEDPQS------------------------ASFDAKTSQALMYYATHTAQIEIVRNDRTLEQIVFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQKKLR-------------SQPLLFWISSYMSLWSNILFNCVVVINMIVAFFYPFDN---TVPELSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGG-EVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRLGLLNTTANSLLPFQ--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ***::**: ******:. **:********* ** * :*** ******** ::: ********:*:*** * : *:::*:***::*:***::**:*: * ::*. *:****:*************:********* ** ******::*:**:***: ** :*:****:* ****.* *:. :* *: **:*:* :*..****: *** . : :******************* *::. : :***** * ***:****:****:***::*.****** **.*:********:***** . * **:** . **:*:* **.**: *.:**:.****::::*:***: :*. *** ::::*: : . *******:: *. *:********* :* : . : . : *:** .**:*:::*: . . . .*.. ..:* *:****:*:: ** *:* :::.** : : .: *::: : : :: : :**** ** **:*******:***:* .** ****::********************** *::*** *:*: * :.************ :*.*******: :*. * ***:.*: ::* . * : . * .* .: * : ::.*** **:**:.**::*****:: :* * ::*: *: *: :*::******::*** ******** * *:::****:***: :::.:** . . : : :* *: *:::** :* . * : *:* ** *** **:.*:*****.* :** **: **.*:* . .* ::* .:. ::: :.* : **:***:::*******.******:: :*.::* ** : . ::: * :** :* . :::*..**: *****:** *:**..*:* :*:*:*:***** *.: :*:*****:: .**:.** ** .** ** ******** * . .*: ** ** :.*:* :.****:*:..* *:*:*** .*:. * * *:: :* *** ** .* **.***:*:.***.* :*** *: ** :* **.*:.: *::**:* :** : *: **:*:::*:.::::.** :* ** ..*:**:::*.* *: : :* .. . : **: **.*** *: **** **:**..**.*:::* :: : * .*** **::*:****:**********:*.*:*.**:. * :*: : *: * : : ** * ** ..: : ::: . :***.. *: .* * .: .:* *::.*: :* *.* :* :*: :: : : : : *** **.:: **.:. * ::**:*:***:*: .*:** : : . *.*: ***.**: *:: .:*::*:*:*:**::*: : :. . **: *: .* . :: * **. *.:.*. ::: . . . .:* *.: *.* ** ***. * .:. : :. .: **:*: ::*: ** : :::*:** ::. : :: .. :. : :*:****::******** ::**:** ****.* ***.*** *** :****************: ** *: *.:*::********::**.**. **.**:*** ***:. *.** . *::***:**:********:**** ******:** .:.*.:**:: ** * . .::********. **::*.* * **. .* .* :*:****** **::******: **.:** ::* :: :*:*:****: :** : . :.***.**:::* . ::* : :::*..: ** .*.:*: :*:*** . :* . :: .. : : :: : .* * :**. .: * :.::*::** *:: :: * :* * *: . *:: * :***:****:: *****.**::***:***.*.*** *.:********:*::::::** : *: : *: *::* **::*.:.:***.***:.*:** *..* :* ***:*****:*:*************************:** :********.*:*. ******:****** ***:*:** *:**:: *: *::******* *: *:****::****. :.:.** *:* :* :* * :: :*: ** ***::******.:**:*::. ", "identical_positions": 1058, "similar_positions": 696, "identity": "35.22%" }, { "cls_id": "homologset.agr.FB:FBgn0010052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z5G7-1", "uniprot_id": "D3Z5G7_MOUSE", "id": "D3Z5G7-1", "name": "Carboxylic ester hydrolase", "aln": "--------------------------------------------------------------------------------------------MWLHALVWASLALCPIWGHSPS---SPVVDTTQGKILGKY-----------TSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTK----SSLLPVMVWIHGGGLMTGGAS--LYNGLALSAHENVVVVTIQYRLGIWGLFSTG---DEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLVACDLS-QMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMSTVIDG-----VVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKMNEETASLLLRRFHSDLNIS----ESLIPAVIEKYLRGTDDP---AKKRDLLLDMFSDVFFGIPAVLLSR-SLRDAGVSTYMYEFRYRPSF------VSDKRPQTVEGDHGDEIFSVFGIPLLK------EGTSEEETNLSKMVMKFWANFARNGNPNGEG----------LPHWPEYDEKE--GYLQIGATTQQAQRLKAEEVAFWTELLAKNPPE--TDPTEHREHK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23953-1", "uniprot_id": "EST1C_MOUSE", "id": "P23953-1", "name": "Carboxylesterase 1C", "aln": "--------------------------------------------------------------------------------------------MWLHALVWASLAVCPILGHSLL---PPVVDTTQGKVLGKY-----------ISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTK----SSQLPVMVWIHGGGLVIGGAS--PYNGLALSAHENVVVVTIQYRLGIWGLFSTG---DEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKKNIQAVN---EIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLVQY-----------NISLSTMIDG-----VVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWIIPMMLQNLLPEGKMNEETASLLLRRFHSELNIS----ESMIPAVIEQYLRGVDDP---AKKSELILDMFGDIFFGIPAVLLSR-SLRDAGVSTYMYEFRYRPSF------VSDKRPQTVEGDHGDEIFFVFGAPLLK------EGASEEETNLSKMVMKFWANFARNGNPNGEG----------LPHWPEYDEQE--GYLQIGATTQQAQRLKAEEVAFWTELLAKNPPE--TDPTEHTEHK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VCC2-1", "uniprot_id": "EST1_MOUSE", "id": "Q8VCC2-1", "name": "Liver carboxylesterase 1", "aln": "--------------------------------------------------------------------------------------------MWLCALSLISLTACLSLGHPSL---PPVVHTVHGKVLGKY-----------VTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQ----NSRLPVMVWIHGGGLVIDGAS--TYDGVPLAVHENVVVVVIQYRLGIWGFFSTE---DEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGR--AARPLA-KKIAALAGCKTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDG-----VLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILNIS----EKLIPAAIEKYLGGTEDP---ATMTDLFLDLIGDIMFGVPSVIVSR-SHRDAGAPTYMYEYQYRPSF------VSDDRPQELLGDHADELFSVWGAPFLK------EGASEEEINLSKMVMKFWANFARNGNPNGEG----------LPHWPEYDQKE--GYLQIGVPAQAAHRLKDKEVDFWTELRAKETAER-SSHREHVEL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3R0-1", "uniprot_id": "EST2A_RAT", "id": "Q8K3R0-1", "name": "Pyrethroid hydrolase Ces2a", "aln": "-------------------------------------------------------------------------------------MPLARLPGWLYVVACGLLLLLQHVHGQDS--ASPIRNTHTGQVRGSF-----------VHVKDTKSGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQ--TDIMNLDGIKEMKLTVHPTPMSEDCLYLNIYTPAHARE----GSNLPVMVWIHGGGLVLGSAS--MNDASTLAATEEIVIVSIQYRLGVLGFFSTG---DQNARGNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHVVSPMSKGLFHGAIMQSGVALLPDLISDKSEVVY---KTVANLSGCEAPDSEALIRCLRAKSKQEILAIN---------------QVFKMIPGVVDG-----KFLPKHPQELLASGDFHPVPSIIGINTDECGWGIPVFLGLDHIIKKITRETLPTVLKSTAAQMMLP----PECIDLIMEEYMGDTENP---ETLQEQFRHMLGDFMFVIPALQVAH-FQR-SQAPVYFYEFQHLPSF------IKQVRPSHVKADHGDDILFVFGSYLWG----MTFDLTEEEELLKRRVMKYWANFARTGNPNGED----------LPHWPVLDHDE--QYLQLNTQPAVGRALKARRLQFWTKTLPQKIQELKGSQSKHAEL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZR3-1", "uniprot_id": "EST2A_MOUSE", "id": "Q8QZR3-1", "name": "Pyrethroid hydrolase Ces2a", "aln": "-------------------------------------------------------------------------------------MPLARLPGWLCVVACGLLLLLQHVHGQDS--ASPIRNTHRGQVRGSF-----------VHVKDTKSGVHAFLGIPFAKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQ--PDIMNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQE----GSNLPVMVWIHGGGLVVGSAS--MNDVSKLAATEEIVIVAIQYRLGVLGFFSTG---DQHARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDTSEVVY---KTVANLSGCEATDSEALIHCLRAKSKQEILAIN---------------QVFKMIPAVVDG-----EFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDHIIKNITRETLPAVLKNTAARMMLP----PECSHLLVEEYMGDTEDP---ETLQAQFREMLGDFMFVIPALQVAH-FQR-SQAPVYFYEFQHLSSF------IKHVRPSHVKADHGDDVAFVFGSYLWD----MNLDLTEEEELLKRMMMKYWANFARNGNPNSEG----------LPSWPVLDHDE--QYLQLDTQPAVGRALKARRLQFWTKTLPQKIQELKGSQDKHAEL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70631-1", "uniprot_id": "EST2C_RAT", "id": "O70631-1", "name": "Acylcarnitine hydrolase", "aln": "-------------------------------------------------------------------------------------MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKL-----------DHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQN-IDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHE----GSNLPVMVCIHGGALVIGMAS--MCDGSLLAVNEDLVVVAIQYRLGVLGFFSTG---DEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVS---TTVAKLSGCEATDSETLVRCLRAKSGAEILVIN---------------KVFKMIPAVVDG-----EFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLP----PECGDLLMEEYMGNTDDP---QTLQIQYAEMMGDFLFVIPALQVAH-FQR-SHAPVYFYEFQHAPSY------FKNVRPPHVKADHADEVPFVFGSFFWG----IKVDFTEEEKLLSRRMMKYWANFARHGNPNSEG----------LPYWPVLDHDE--QYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WG0-1", "uniprot_id": "EST2C_MOUSE", "id": "Q91WG0-1", "name": "Acylcarnitine hydrolase", "aln": "-------------------------------------------------------------------------------------MTRNQLHNWLNAGFFGLLLLLIHVQGQDSPEANPIRNTHTGQIQGSL-----------IHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQN-LDMLNEAGLPDMKMMLSSFPMSEDCLYLNIYTPAHAHE----GSNLPVMVWIHGGALVIGMAS--MFDGSLLTVNEDLVVVTIQYRLGVLGFFSTG---DQHARGNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVALLPDLISETSEMVS---TTVAKLSGCEAMDSQALVRCLRGKSEAEILAIN---------------KVFKMIPAVVDG-----EFFPRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSAQMIKGITRENLQAVLKDTAVQMMLP----PECSDLLMEEYMGDTEDA---QTLQIQFTEMMGDFMFVIPALQVAH-FQR-SHAPVYFYEFQHPPSY------FKDVRPPHVKADHADEIPFVFASFFWG----MKLDFTEEEELLSRRMMKYWANFARHGNPNSEG----------LPYWPVMDHDE--QYLQLDIQPAVGRALKAGRLQFWTKTLPQKIQELKASQDKHREL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7J5-1", "uniprot_id": "EST2E_RAT", "id": "G3V7J5-1", "name": "Pyrethroid hydrolase Ces2e", "aln": "---------------------------------------------------------------------------MAQTRAWKSIMPLESLPGWLNAVVWGLLLLFCQVQGQDS--ASPIRNTHTGQVRGSF-----------VHVKDTKSGVHTFLGIPFAKPPIGPLRFAPPEPPEPWSGVRDGTSHPAMCLQN-IDGLNLENLK-IKMSRSPVSMSEDCLYLSIYTPAHTHK----DSNLPVMVWIHGGGLCWGMAS--TYDGSMLAAIEDVVVVTIQYRLGILGFFSTG---DEHARGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIY---TMVANLSGCEPVDSEALMSCLREKSEEEMLAIN---------------NIVRTISGVVDG-----KFLPRHPLELLASVDFHPVPSIIGINSDEYGWIIPMLH-PDSTMKEINRETMRAVLKNTAVQMMLP----PECSDLLMEEYMGDTEDS---KTLQIQFNEMMGDFIFVIPALQVAH-FQR-SHAPVYFYEFQHQSNF------LKDIRPPHVKADHGDELPYVIGYLFWD----MKFVFTEEEKLLSRKMIKYWANFARHGNPNSEG----------LPYWPALDHDE--QYLQLDIQPVVGRALKARRLKFWTKTLPQKIQELKGSQDNHTEL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5GRG2-1", "uniprot_id": "EST5A_RAT", "id": "Q5GRG2-1", "name": "Carboxylesterase 5A", "aln": "-------------------------------------------------------------------------------------MSGDWVHTGQ-ALIWVLWIFAAIIRGSVT--EEPHRYTRLGWVQGKQ-----------ATVLGRLEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQN-LEWL-FIYQNLLKVHYPKLGVSEDCLYLNIYAPAYAND----GSRLPVMMWIPGGGFETGSAS--IFDGSALAAYEDVLIVTIQYRLGIFGFFNTQ---NQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGL-QVVADVCKCNVSDSKVLLKCLREKSSLELLSLG---------------QKTKAFTRVVDG-----SFFPEEPMELLSQKTFKTVPSIIGVNNQECGYILPMREAPEILFG----SNESTALTLIHVLLHIP----PQYMHIVAKDYFHGKHSL---TDIRDTLLDLFGDVFFVVPGLVTAR-NHRDADGPVYFYEFQHRPNC------FQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDD----------LPLWPAYDQNE--SYLKLDVNISTGWRLKDRRVEFWTDTLPLIMSASKALLSPTFPLILFSLLPPSLLSIAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AW46-1", "uniprot_id": "EST5A_MOUSE", "id": "Q6AW46-1", "name": "Carboxylesterase 5A", "aln": "-------------------------------------------------------------------------------------MSGDWVRPGQ-ALIWVIWIFGAIIEGSVT--EEPHRYTKLGWVQGKQ-----------ATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQN-LEWL-FIYQNLLKVSYPILGMSEDCLYLNIYAPCHANN----GSSLPVMVWIPGGGFETGSAS--IFDGSALAVYEDVLVVTIQYRLGIFGFFTTQ---NQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDL-QVVANVCDCNVSDSKALLKCLREKSSLELMSLS---------------QKAKSFTRVVDG-----SFFSEEPLELLSQKTLKIVPSIIGVNNQECGYILPVRDTPEILLG----SNESTALTLIHTLLHIP----TQHLYIVTKEYFHGKHSP---TDIRDTLLDLFGDVFFVVPGLVTAR-YHRDSGGPVYFYEFQHRPHC------FQNSRPAFVKADHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGAD----------LPPWPVYDENE--QYLELDVNISTGRRLKDQRVEFWTDTLPLILSASKALLSPTFSLILLSLLSPVLLSAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XG92-1", "uniprot_id": "EST4A_HUMAN", "id": "Q5XG92-1", "name": "Carboxylesterase 4A", "aln": "-------------------------------------------------------------------------------------------MRWILCWSLTLCLMAQTALGALHT-KRPQVVTKYGTLQGKQ-----------MHVG--KTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVS-TRERYKWLRFSEDCLYLNVYAPARAPG----DPQLPVMVWFPGGAFIVGAAS--SYEGSDLAAREKVVLVFLQHRLGIFGFLSTD---DSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVA---KKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDG-----VVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNIT----KEQVPLVVEEYL-DNVNEHDWKMLRNRMMDIVQDATFVYATLQTAH-YHRDAGLPVYLYEFEHHAR-------GIIVKPRTDGADHGDEMYFLFGGPFAT------GLSMGKEKALSLQMMKYWANFARTGNPNDGN----------LPCWPRYNKDE--KYLQLDFTTRVGMKLKEKKMAFWMSLYQSQRPEKQRQF---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0W5-1", "uniprot_id": "EST4A_MOUSE", "id": "Q8R0W5-1", "name": "Carboxylesterase 4A", "aln": "------------------------------------------------------------------------------------MAEAGWNMKWILGLSLTLCLVVQTALGALHT-KEPLLITKHGILQGKQ-----------VHVG--DTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLN-TRKQYKWLHFSEDCLYLNVYAPVLAPG----APLLPVMVWFPGGAFLAGSAS--TYEGSELAARGKVVLVFLQYRLGILGFFSTG---NSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSA---KKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVDG-----VVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNIT----KEQVPVVAREYLNDAISNHDWKMFRNRLIDLIGDATFVYATLQAAR-YHRDAGSPVYLYEFKHHASS------GIIIKP-YNGADHGDELSYLFGSPFSK------GSSAGEEKEFSLQMMKYWANFAHTGNPNGEK----------LPYWPRFDKDE--KYLQLDFDTRVGVKLKEKKMAFWSQLRQSQKP---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PCX7-1", "uniprot_id": "A0A8M9PCX7_DANRE", "id": "A0A8M9PCX7-1", "name": "Carboxylic ester hydrolase", "aln": "MGSSCTTSILLALLSMTVVLNGREERKPQQKSFNVDTEYRTMMFNIPNIEHNRKHEIALDDTFLEESLNLIKSLEFYGNADDTGLVESTPDSTNIVHKDPEIDITVHDAANKAESILNSLNNTSSDGLEDGSGADPVVVTLLGRVRGLTLEKAHVFYGIPYADPPVGDKRWAPPSPVSPWLYTYNATFPRPACMQMCAGEFSRLCPP---------EVSEDCLYLNVFVPVSVNLSLPKVTALPVMVWIHGGDFIAGSASKPLYDGRYISNYSNTVVVNMEYRLGAFGFLVTGKDPESSAVGNYGILDQQAALHWVQENIAAFGGDPNKVTLFGESAGAQSVSLHLMMQSSETLFRHAAIQSLPFSLPLKTRWDAMKLG---WDFAKLTNCSVFD----LPCMRSLSSEDVLNAQIKSGSKIIN-PFRFLEVFETWGPFIDG-----QLLKEQPITAFQKGHWQSYKPVILGTTSEEGVMFVYRN----------FNKSVSMLECVLYTAAIF----KQHALKILHKYIPFYRNQ----DRRVMLSQMVTDYVFSCPARQSAR-SGVKVGGAVWMYVFDHAPSDPNI---WAELTFCYNHSCHGAELPFLFDSAPSTN-----FTFTPQERLLANRMACYWGMFAHTGDPNSRDEQTHFCREQRLPVWPRYTDIGGWTILNLTLQSHPQHGSRDHFCDFWDRLDIY------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA98-1", "uniprot_id": "A1ZA98_DROME", "id": "A1ZA98-1", "name": "Carboxylic ester hydrolase", "aln": "--------------------------------------------------------------------------------------MIQQRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTN------------LQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYG-----------DEDCLYLNVYRPEIRKS------ALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQ---DAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWD-------VDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVN--ELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFP----DFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSES--------LTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLWSHILNEK------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . .* *:*:: .*:* *:: *. . : * * .******.:: * ****: : ** : . *. : . ::* : :*** *:: * : **:. ** ** **: ** ***: **:** *:*. : :: . **: . * .* : . .:* . .: .:: .: * : :: * . : . . *: . .:. * * . : ..::* : : * :: : * . . :: **: *.*.. * . . : . ", "identical_positions": 66, "similar_positions": 95, "identity": "8.97%" }, { "cls_id": "homologset.agr.FB:FBgn0010078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PC14-1", "uniprot_id": "RL23_DANRE", "id": "Q6PC14-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPSAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62830-1", "uniprot_id": "RL23_MOUSE", "id": "P62830-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62829-1", "uniprot_id": "RL23_HUMAN", "id": "P62829-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62832-1", "uniprot_id": "RL23_RAT", "id": "P62832-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y4M0-1", "uniprot_id": "A0A8I5Y4M0_RAT", "id": "A0A8I5Y4M0-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48159-1", "uniprot_id": "RL23_DROME", "id": "P48159-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGTAGGKFRISLGLPVGAVMNCADNTGAKNLYVIAVHGIRGRLNRLPAAGVGDMFVATVKKGKPELRKKVMPAVVIRQRKPFRRRDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNASSIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX41-1", "uniprot_id": "RL23A_YEAST", "id": "P0CX41-1", "name": "Large ribosomal subunit protein uL14A", "aln": "MSGN---GAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX42-1", "uniprot_id": "RL23B_YEAST", "id": "P0CX42-1", "name": "Large ribosomal subunit protein uL14B", "aln": "MSGN---GAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . *: * ******** ***::* **.:*::*:*:*:*: .**:***:*.:*.*.:***:*.:*:***** **:*:** *. *:*** :***::* **.* **:*********:.** ** ***:***:. .", "identical_positions": 79, "similar_positions": 39, "identity": "56.43%" }, { "cls_id": "homologset.agr.FB:FBgn0010097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A5N2-1", "uniprot_id": "A0A8I6A5N2_RAT", "id": "A0A8I6A5N2-1", "name": "Tubulin gamma chain", "aln": "MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGI--VEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSSYAKLYNPENIYLSEHGGGAGNNWARGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD-QSVASVRK-TTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS---AHRVSGLMMANHTSISSLFESSCQQYDKLWKRGAFLEQFRKEDIFK---DNFEEMDRSREVVQELIDEYHAATRPDYISWGTQEQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCK3-1", "uniprot_id": "TBG2_MOUSE", "id": "Q8VCK3-1", "name": "Tubulin gamma-2 chain", "aln": "MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGI--VEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSSYAKLYNPENIYLSEHGGGAGNNWGRGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD-QSVASVRK-TTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS---AHRVSGLMMANHTSISSLFESSCQQYDKLWKRGAFLEQFRKEDIFK---DNFEEMHRSREVVQELIDEYHAATRPDYISWGTQEQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRH3-1", "uniprot_id": "TBG2_HUMAN", "id": "Q9NRH3-1", "name": "Tubulin gamma-2 chain", "aln": "MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGI--VEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD-QSVASVRK-TTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS---AHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFK---DNFDEMDRSREVVQELIDEYHAATQPDYISWGTQEQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42271-1", "uniprot_id": "TBG2_DROME", "id": "P42271-1", "name": "Tubulin gamma-2 chain", "aln": "MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPDGV--LEDFATDGQDRKDVFFYQADDNHYIPRAVLIDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASGFSQGEKVQEEVFDILDREADGSDSLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIPTPQLHFLMTGYTPLMSDCETKTSVRK-TTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQS---AHKVSGLMMANHTGISSLFKRALAQYDKLRKRNAFLDNFRRESMFQ---DDLTELDIARDTVDCLVQEYEAATQIDYPQWSPAVEASKAG---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53378-1", "uniprot_id": "TBG_YEAST", "id": "P53378-1", "name": "Tubulin gamma chain", "aln": "MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVEN-TFRGFFDPRNTWVASDGASAGNSWANGYDIGTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPARS--SEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMN---NPTYFNVYNTIIGNVEPRQISRAMTKLQQR--IKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMEDYVAAEQDSYLDDVLVDDENMVGELEEDLDADGDHKLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ****** *****::* :*.:*. **.*..:*: : : :*: * .. ** : . ::: ***:::* ** ** .: . .: ::: .* :::..*..***.*. *:. * : :::::: :*:* *.:*.:*** * **:*******:** :** * :*:***:: ****** :. *:****.**::*:*:** : :*..**:**::* .*: . :: . : : *:*:***:* *.::*:*.** ..: .: ::***:*.**** ..:**: :* .:* : *** **:*.* :**: : . :. : * * *:*:* *: ::: ::::* :* .*..::::* : * ***: :.***:*::* : : .:*: : :**: :.***:::. .:*: : *: :*:.*: *:::* ** : .* . : ", "identical_positions": 155, "similar_positions": 177, "identity": "32.22%" }, { "cls_id": "homologset.agr.FB:FBgn0010100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER34-1", "uniprot_id": "ACON_RAT", "id": "Q9ER34-1", "name": "Aconitate hydratase, mitochondrial", "aln": "MAP----YSLLVTRLQKALG-----VRQYHVASALCQRAKVAMSHFEPSEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGTLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLAEEFKDHLVP-DPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRSDFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQGLKDFAPGKPLNCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KI0-1", "uniprot_id": "ACON_MOUSE", "id": "Q99KI0-1", "name": "Aconitate hydratase, mitochondrial", "aln": "MAP----YSLLVTRLQKALG-----VRQYHVASVLCQRAKVAMSHFEPSEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRTDIANLAEEFKDHLVP-DPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRSDFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQGLKDFAPGKPLKCVIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99798-1", "uniprot_id": "ACON_HUMAN", "id": "Q99798-1", "name": "Aconitate hydratase, mitochondrial", "aln": "MAP----YSLLVTRLQKALG-----VRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGREDIANLADEFKDHLVP-DPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIE8-1", "uniprot_id": "Q9VIE8_DROME", "id": "Q9VIE8-1", "name": "Aconitate hydratase, mitochondrial", "aln": "MAARLMNAQAQVCRLGKHVASEATVVRQFHAS--CYTASKVALSKFDSDVYLPYEKLNKRLEVVRGRLNRPLTLSEKVLYSHLDDPANQDIVRGTSYLRLRPDRVAMQDATAQMALLQFISSGLKKVAVPSTVHCDHLIEAQIGGPKDLARAKDLNKEVYDFLASTCAKYGLGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKVIGVNLTGKISGWTSPKDVILKVADILTVKGGTGAIIEYHGKGVDSISCTGMATICNMGAEIGATTSLFPFNQRMADYLKSTGRAGIASEAQKYQAKILSADKNCEYDELIEINLDTLEPHVNGPFTPDLGHPISKLGENSKKNGYPMDIRVGLIGSCTNSSYEDMGRCASIAKDAMSHGLKSKIPFNVTPGSEQIRATIERDGISEVFDKFGGTVLANACGPCIGQWDRKDVKKGDKNTIVTSYNRNFTGRNDANPATHCFVTSPELVTALSIAGRLDFNPLTDELTGADGKKFKLKAPFGDELPAKGFDPGQDTYTAPPPSGENVKVAVDPKSTRLQLLEPFDKWNGQDLTDLTVLIKVKGKCTTDHISAAGPWLKYRGHLDNISNNMFIGATNYENNEMNNIKNQRNGSWGGVPDVARDYKANGIKWVAVGDENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGLLPLTFANPADYDKIQPTSKISLLNLKSLAPGKPVDAEIKNGD-KVERIKLNHTLNDLQIGWFKAGSALNRMKELAQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19414-1", "uniprot_id": "ACON_YEAST", "id": "P19414-1", "name": "Aconitate hydratase, mitochondrial", "aln": "---------MLSARSAIKRP----IVRGLATVSNLTRDSKVNQNLLEDHSFINYKQNVETLDIVRKRLNRPFTYAEKILYGHLDDPHGQDIQRGVSYLKLRPDRVACQDATAQMAILQFMSAGLPQVAKPVTVHCDHLIQAQVGGEKDLKRAIDLNKEVYDFLASATAKYNMGFWKPGSGIIHQIVLENYAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGRPWELKAPKILGVKLTGKMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGMGTICNMGAEIGATTSVFPFNKSMIEYLEATGRGKIADFAKLYHKDLLSADKDAEYDEVVEIDLNTLEPYINGPFTPDLATPVSKMKEVAVANNWPLDVRVGLIGSCTNSSYEDMSRSASIVKDAAAHGLKSKTIFTVTPGSEQIRATIERDGQLETFKEFGGIVLANACGPCIGQWDRRDIKKGDKNTIVSSYNRNFTSRNDGNPQTHAFVASPELVTAFAIAGDLRFNPLTDKLKDKDGNEFMLKPPHGDGLPQRGYDAGENTYQAPPADRSTVEVKVSPTSDRLQLLKPFKPWDGKDAKDMPILIKAVGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAENKKANCVKNVYTGEYKGVPDTARDYRDQGIKWVVIGDENFGEGSSREHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDRIDILGLAELAPGKPVTMRVHPKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIKADEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** . :** . :: :: *. : :::** *****:* :**::*.***** .*:* ** :**:******* ********:***:*:** :** * *:******:**:** *** ** *:*:***:***:: ***.:***:*********:*****:** *:*********.**** :.*************. *****.**::**:***.:.**:****:***:*.* ******* *:**.* ***::*.***.**************:**:*: * .**. *** **. *. :: .::. * ...**:::**:*. *:*::********. *::.: : :.:*:*:****************.*.*::.*:* :****.* *.:*************** : : ..** ***************:*:***:*****:*******.***.** **.**:***:***::*** * *** ** *.. **::* *:.* .* ** :*.*::** ** . . .* *.*.* *****:**. *:*:* *: :***. ** ****** ******:****:***** :*** * ** : * ::* . .: ***.** *: :**:**.:****:**************.*** ***.*******************.* :*:**:**:* .:: : .* .::****: :: : . *.**:*: ** **: *****::* : ", "identical_positions": 452, "similar_positions": 186, "identity": "57.14%" }, { "cls_id": "homologset.agr.FB:FBgn0010109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14469-1", "uniprot_id": "HES1_HUMAN", "id": "Q14469-1", "name": "Transcription factor HES-1", "aln": "--MPADIMEKN---SSSPVAATPASVNTTPD-KPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAM-----TYPGQPHPALQAPPPPPP-GPGGPQ-------HAPFAPPPP------------------LVPIPGGAAPPPGGAPCK---LGSQAGEAAKVFGGFQ--------------------------------VVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVG----------------------------------------------------------------------------------PNAVSPSSGPSLTADSMWRPWRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04666-1", "uniprot_id": "HES1_RAT", "id": "Q04666-1", "name": "Transcription factor HES-1", "aln": "--MPADIMEKN---SSSPVAATPASVNTTPD-KPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAM-----TYPGQAHPALQAPPPPPPSGPGGPQ-------HAPFAPPPP------------------LVPIPGGAAPPPGSAPCK---LGSQAGEAAKVFGGFQ--------------------------------VVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVG----------------------------------------------------------------------------------PNAVSPSSGSSLTADSMWRPWRN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35428-1", "uniprot_id": "HES1_MOUSE", "id": "P35428-1", "name": "Transcription factor HES-1", "aln": "--MPADIMEKN---SSSPVAATPASVNTTPD-KPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAM-----TYPGQAHPALQAPPPPPPSGPAGPQ-------HAPFAPPPPP-----------------LVPIPGGAAPPPGSAPCK---LGSQAGEAAKVFGGFQ--------------------------------VVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVG----------------------------------------------------------------------------------PNAVSPSSGSSLTSDSMWRPWRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCC6-1", "uniprot_id": "HES4_HUMAN", "id": "Q9HCC6-1", "name": "Transcription factor HES-4", "aln": "--MAADTPGKP---SASPMAGAPASASRTPD-KPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHL---AACLRQLGPS-----RRP------------------------------ASLSPAAP------------------------AEAPAP------------------EVYAGRP--------------------------------LLPSLGGPFPLLAP--------PLLPGLTR--ALPAA----------------------------------------------------------------------------------PRAGPQGPG------GPWRPWLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q26263-1", "uniprot_id": "DPN_DROME", "id": "Q26263-1", "name": "Protein deadpan", "aln": "MDYKNDINSDDDFDCSNGYSDSYGSNGRMSNPNGLSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRTESSAPAIQMGGLQLIPSRLPSGEFALIMPNTGSAAPPPGPFAWPGSAAGVAAGTASAALASIANPTHLNDYTQSFRMSAFSKPVNTSVPANLPENLIHTLPGQTQLPVKNSTSPPLSPISSISSHCEESRAASPTVDVMSKHSFAGVFSTPPPTSAETSFNTSGSLNLSAGSHDSSGCSRPLAHLQQQQVSSTSGIAKRDREAEAESSDCSLDEPSSKKFLAGAIEKSSSAWRPW--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:. : : .* . .: : : :* **:.**:**********..* :**:***:*::*:.:**:************:**:.::* *:. *:.:**:*: *:::** ** **.*::: :*: : ** ** .** * .: *:.. . :*. . **.* . .. :: : * : *: . : .. * : .* . **** ", "identical_positions": 76, "similar_positions": 75, "identity": "17.39%" }, { "cls_id": "homologset.agr.FB:FBgn0010113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M590-1", "uniprot_id": "F1M590_RAT", "id": "F1M590-1", "name": "", "aln": "MPNPKNSKGGRKNKRANSSGDEQENGAGALAAAGATGAAAGGALAAAAGCGAVSLGAVGTGGAAGPGGAGTGAANATIAAGAAAAGDAKNEAPCATPLICSFGRAVDLEKDDYQKVVCNNEHCPYSTWMHLQCFYEWESSILVQFNCIGRARSWNEKQCRQNMWTKKGYDLAFRFCSCRCGQGHLKKDTDWY---------------------------QVKRMQDEKKKKSGSEKNTARPPGEAGEEAKKCRPLNKPQKGLSHDLPRRHSMDRQNS----------------------------------------------QEKTVSSAAYGARSPCGSPGQSPPTGYSILSPAHFSGPRSSR--------------YLGEFLKNAIHLEPHKKAMPGGHVFRSAHFDYSSAG---------------------------------LSVHRAGHFDTPVQFLRRLDLSELLTHIPRHKLNTFHVRMEDDAQVGQGEDLRKFILAALSASHRNVVNCALCHRALPVFEQFPLVDGTLFLSPSRHDEIEYDVPCHLQGRLMHLYAVCVDCLEG---VHKIICIKCKSRWDGSWHQLGTMYTYDILAASPCCQARLNCKHCGKPVIDVRIGMQYFSEYSNVQQCPHCGNLDYHFVKPFSSFKVLEAY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBI9-1", "uniprot_id": "HDC_HUMAN", "id": "Q9UBI9-1", "name": "Headcase protein homolog", "aln": "MPNPKNSKGGRKNKRANSSGDEQENGAGALAAAGAAGAAAGGALAAAAGCGAAAAGAPGAGGAAGAGGAGTGAANAAAAAGAAAAGDAKNEAPCATPLICSFGRPVDLEKDDYQKVVCNNEHCPCSTWMHLQCFYEWESSILVQFNCIGRARSWNEKQCRQNMWTKKGYDLAFRFCSCRCGQGHLKKDTDWY---------------------------QVKRMQDEKKKKSGSEKNTGRPPGEAAEEAKKCRPPNKPQKGPSHDLPRRHSMDRQNS----------------------------------------------QEKAVGAAAYGARSPGGSPGQSPPTGYSILSPAHFSGPRSSR--------------YLGEFLKNAIHLEPHKKAMAGGHVFRNAHFDYSPAG---------------------------------LAVHRGGHFDTPVQFLRRLDLSELLTHIPRHKLNTFHVRMEDDAQVGQGEDLRKFILAALSASHRNVVNCALCHRALPVFEQFPLVDGTLFLSPSRHDEIEYDVPCHLQGRLMHLYAVCVDCLEG---VHKIICIKCKSRWDGSWHQLGTMYTYDILAASPCCQARLNCKHCGKPVIDVRIGMQYFSEYSNVQQCPHCGNLDYHFVKPFSSFKVLEAY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9N2M8-1", "uniprot_id": "HECA_DROME", "id": "Q9N2M8-1", "name": "Headcase protein", "aln": "-------MAPRRNSNISSSGNSTQQQHQQQLQQQHQTQQHQLLQFYAENVNSSGVLMAPMQGTGGVGGVGGGGMVHCCLP----SGDCR--------KLDTLIHLNELSLADCIRVLCNNENCSAGQYMHRECFEWWEASVLQALKANGRARSWSERQRLQHLWTKKGYELVQKACSCKCGRGQLRKDLDWVPPSSQGVIYLNGSGNRPTLANGSLSEDDDKKKAKKKRNRNNNNNNGGGGGGGAGVNGNTKTPLSNNNGNSYAGLTPNPNVGVIGSGLPHNNGNTASNGSSGNNGSSGVLQTSALATFSNILNTNNVLGLDLRARAGSLSSSGAGSGSTSPSDSQSSGEISVSPVQQLLPQQQQQQQQSLLIQPLGPAFGSNLLQNGLGLSKNLLIAPQQQQQQQLQQQQQQQNNLPALANISNFKPLASYEQQQLVQQQKNKEVELYSDRVRSTSGCNGIFSRRLDFSSFN-LLPKTRLNSYQVKIEDEGNHGN-DETRLFILSSLAQSQMSRVACILCEEPLLVFDRYPLVDGSFFLSPKQHSSGCIEV--KYEGRTLYLTCVCMSCLDGTSSSRAINCRFCKEPWDGSSLVLGTMYAYDIFAAMPCCAERFKCNNCFKMLMHPQQRLSFYSDYSHGVTCPYCNTQDTHFVKPLTFCYAKTTATRLPTLAXHEAPLESPVGTGATTTQVPNAQGSPTASGCSSNTIASKQPPKQPLYNAAIDYSAPLQQQINPDLIGAHPHAQQHQQQVRQQQQQQQQQQPQQQQQQQQQQTQQQQSQQQQQQQQQQHQPVVSTFQRGNFPQQSHKTMNMMAMADVMSKYQQQQHQQQQQQRQQQHNLQPQQQHATQKGLEGLLLTNTNTSNNNSSSSSSSSISNLIISHNSASNTGNKMQPTWGQSDAISALWGCSSSSSGCSSGSGSQPSLSPTASSNGNDGSKMMLWAAQSSPQNAATLRDGFKELQRQQPPQQQVPQQQPHAASPTASLTSSSSSSNGWSASHYGKPNIWELPGSTGQRTPASSHDIFTDLLCNLSISQDNSSQQASSKADASDVSSNSSSSAGELLEAANIWRFPEYASSQLYMEEPTGGAAACMQLFNDYLNMN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:*.. .***:. :: * . .: . *:.* **.* *. . :**.: : :: : :*. * :*:****:*. . :** :** **:*:* ::. ******.*:* *::******:*. : ***:**:*:*:** ** : *: .:*:::...::* . * *. :.:. * .: : . .*. . .:. .* : :: . :: ** * **.:* .:* :**.: *:..: : .::*:*.: *. : . : :. : : . . : : . . * ****:*.: :*: :**:::*::**:.: *: :: * ***::*: *: . * * **...* **:::*****::****.:*.. :* : :** ::* .**:.**:* : * * **. **** *****:***:** *** *::*::* * ::. : :.::*:**: **:*.. * *****:: . : ", "identical_positions": 160, "similar_positions": 185, "identity": "14.51%" }, { "cls_id": "homologset.agr.FB:FBgn0010173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VEE4-1", "uniprot_id": "RFA1_MOUSE", "id": "Q8VEE4-1", "name": "Replication protein A 70 kDa DNA-binding subunit", "aln": "-MVGHLSEGAIEVMIQQENTSIKP---ILQVINIRPISTGNRSPRYRLLMSDGLNTLSSFMLATQLNTLVEGGQLASNCVCQVHKFIVNTLKD---GRKVVVLMDLEVMKSAEDVGLKIGNPVPYNEGYGQQQQQQQQQQQQAVPSPASAATPPAS-KPQPQNGSLGMGSTAAKAYGASKPFGKPAGTGLLQPSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGALKIANKQFSAVKNDYEMTFNNETSVLPCEDGHH--LPTVQFDFTGIGDLESKAKDALVDIIGICKSYEDSIKITVKSNNREVAKRNIYLMDMSGKVVTTTLWGEDADKFDGSRQPVMAIKGARVSDF-GGRSLSVLSSSTVIVNPDIPEAYKLRGWFDSEGQALDGVSISDHRSGGAGGG------NTNWKTLHEAKSENLGQGDKADYFSTVAAVVFLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDREFPNFKYRMILSANIADFQENQWVTCFQESAEAILGQNTMYLGELKEKNEQAFEEVFQNANFRSFTFRIRVKLETYNDESRIKATVMDVKPVDFRDYGRRLIANIRKNM------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27694-1", "uniprot_id": "RFA1_HUMAN", "id": "P27694-1", "name": "Replication protein A 70 kDa DNA-binding subunit", "aln": "-MVGQLSEGAIAAIMQKGDTNIKP---ILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKD---GRRVVILMELEVLKSAEAVGVKIGNPVPYNEGLGQPQ----------VAPPAPAASPAASSRPQPQNGSSGMGSTVSKAYGASKTFGKAAGPSLSHTSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHH--LPTVQFDFTGIDDLENKSKDSLVDIIGICKSYEDATKITVRSNNREVAKRNIYLMDTSGKVVTATLWGEDADKFDGSRQPVLAIKGARVSDF-GGRSLSVLSSSTIIANPDIPEAYKLRGWFDAEGQALDGVSISDLKSGGVGGS------NTNWKTLYEVKSENLGQGDKPDYFSSVATVVYLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQENQWVTCFQESAEAILGQNAAYLGELKDKNEQAFEEVFQNANFRSFIFRVRVKVETYNDESRIKATVMDVKPVDYREYGRRLVMSIRRSALM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY74-1", "uniprot_id": "RFA1_DANRE", "id": "Q6NY74-1", "name": "Replication protein A 70 kDa DNA-binding subunit", "aln": "-MTVRLSEGAIESLS-KGTEVNNP---ILQCVNIRKIDGGNGVSRFRVMMSDGLHTMSSFMLSTQLNPMAEQNQLATNCVCVLKRSVTNVLKD---GRRVVVILDIEVLKSADQMPGKIGDPTPYVE--GQSK------------APSTAPAPTAR-PLQPQNGSD--GSTYRPS---AQSFGKKPMAAPNTPGG--SSKVVPIASLNPYQSKWTIRARVTNKSAIRTWSNSRGDGKLFSMELVDESGEIRATGFNNEVDKFFSLIEQGKVFYISKGTLKIANKQFSSLKNDYEMTLNGETSIIPCEDSND--VPMLQCDFVSIADLESREKDTILDVIGVCKNAEDVARIMTK-NSREVSKRNIQLIDMSGRVIQLTMWGSDAETFDGSGQPILAIKGARLSDF-GGRSLSTLYSSTVMINPDIPEAYKLRGWYDKEGHALDGQSMTELR-GPGGGG------NTNWKTLAEVKNEHLGHGDKADYFSCIATIVYIRKENCLYQACPSKDCNKKVVDQQNGMFRCEKCDKEFPDFKYRLMLSANIADFGDNQWVTCFQDTAETLLGQNSSYLGQLKDTNEAAFDEVFQHANFNTFVFRNRVKLETYNDESRIKVTVVDAKPVDHREYSKRLIINIRKLAAQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24492-1", "uniprot_id": "RFA1_DROME", "id": "Q24492-1", "name": "Replication protein A 70 kDa DNA-binding subunit", "aln": "MVLASLSTGVIARIM-HGEVVDAP---VLQILAIKKINSAADSERYRILISDGKYFNSYAMLASQLNVMQHNGELEEFTIVQLDKYVTSLVGKDGAGKRVLIISELTVVNPGAEVKSKIGEPVTYENAAKQDL------------APKPAVTSNSK--PIAK-----------------KEPSHNNNNNIVMNSSINSGMTHPISSLSPYQNKWVIKARVTSKSGIRTWSNARGEGKLFSMDLMDESGEIRATAFKEQCDKFYDLIQVDSVYYISKCQLKPANKQYSSLNNAYEMTFSGETVVQLCEDTDDDPIPEIKYNLVPISDVSGMENKAAVDTIGICKEVGELQSFVARTTNKEFKKRDITLVDMSNSAISLTLWGDDAVNFDGHVQPVILVKGTRINEFNGGKSLSLGGGSIMKINPDIPEAHKLRGWFDNGG----GDSVANMVSARTGGGS----FSTEWMTLKDARARNLGSGDKPDYFQCKAVVHIVKQENAFYRACPQSDCNKKVVDEGNDQFRCEKCNALFPNFKYRLLINMSIGDWTSNRWVSSFNEVGEQLLGHTSQEVGEALENDPAKAEQIFSALNFTSHIFKLRCKNEVYGDMTRNKLTVQSVAPINHKEYNKHLLKELQELTGIGSSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22336-1", "uniprot_id": "RFA1_YEAST", "id": "P22336-1", "name": "Replication factor A protein 1", "aln": "MSSVQLSRGDFHSIFTNKQRYDNPTGGVYQVYNTRKSDGANSNRKNLIMISDGIYHMK-ALLRNQAASKFQSMELQRGDIIRVIIAEPAIVRE--RKKYVLLVDDFELVQSRADMVNQTSTFLDNYFSEHPNET-----------LKDEDITDSGNVANQTNASNAGVPDMLHSN---SNLNANERKFANENPNSQKTRPIFAIEQLSPYQNVWTIKARVSYKGEIKTWHNQRGDGKLFNVNFLDTSGEIRATAFNDFATKFNEILQEGKVYYVSKAKLQPAKPQFTNLTHPYELNLDRDTVIEECFDESN--VPKTHFNFIKLDAIQNQEVNSNVDVLGIIQTINPHFELTSR-AGKKFDRRDITIVDDSGFSISVGLWNQQALDFNLPEGSVAAIKGVRVTDF-GGKSLSMGFSSTLIPNPEIPEAYALKGWYDSKGRNANFITLKQEPGMGGQSAASLTKFIAQRITIARAQAENLGRSEKGDFFSVKAAISFLKVDNFAYPACSNENCNKKVLEQPDGTWRCEKCDTNNARPNWRYILTISIIDETNQLWLTLFDDQAKQLLGVDANTLMSLKEEDPNEFTKITQSIQMNEYDFRIRAREDTYNDQSRIRYTVANLHSLNYRAEADYLADELSKALLA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * : : : * : * : . : :::*** . :* .* . :* : : : . : *::: :: :::. : : . : . .: : .: .. .* .*.***. *.* ***: *. *:** * **:****.::::* *******.*:: ** ::: ..*:*.** *: *: *:: :.: **:.:. :* : * * . :* : :: : :.. .: :* :*: : : : .::. :*:* ::* *. : :*..:* *: .: :**.*:.:* **:*** .* : **:****: *:**:* * :: : .. :: *: .: .:** .:* *:*. *.: :: :* * **. .:*****::: :. :*****: . ::* ::. .* * .: *:: *:: .: :** : : . : : :: . :: . *: * : :.*.* :* : ** . .::.: * .: . ", "identical_positions": 123, "similar_positions": 198, "identity": "19.04%" }, { "cls_id": "homologset.agr.FB:FBgn0010194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXQ7-1", "uniprot_id": "WNT5A_RAT", "id": "Q9QXQ7-1", "name": "Protein Wnt-5a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKPIG-----ILSPGVALGTAGGAMSSKFFLMALATFFSFAQVVIEANSWWSLGMNNPVQMSEVHIIGAQ--------------------------------------PLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERI---------------------------------------------------------------------------------------------------------HAKGSYE----------------------------------------SARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22725-1", "uniprot_id": "WNT5A_MOUSE", "id": "P22725-1", "name": "Protein Wnt-5a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKPIG-----ILSPGVALGTAGGAMSSKFFLMALATFFSFAQVVIEANSWWSLGMNNPVQMSEVYIIGAQ--------------------------------------PLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERI---------------------------------------------------------------------------------------------------------HAKGSYE----------------------------------------SARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41221-1", "uniprot_id": "WNT5A_HUMAN", "id": "P41221-1", "name": "Protein Wnt-5a", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKSIG-----ILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEVYIIGAQ--------------------------------------PLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERI---------------------------------------------------------------------------------------------------------HAKGSYE----------------------------------------SARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M064-1", "uniprot_id": "A0ABK0M064_RAT", "id": "A0ABK0M064-1", "name": "Protein Wnt", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKCMMPVSLMLSQERRLRLRRLPMCDRCRRPASEIPPQKLR-LRSLRPVSPREMCFRERSGAPLWKMLVPGHWDGLR-PAMPSLLLLFVAALLSSWAQLLTDANSWWSLALN-PVQRPEMFIIGAQ--------------------------------------PVCSQLPGLSPGQRKLCQLYQEHMSYIGEGAKTGIRECQHQFRQRRWNCSTVDNLSVFGRVMQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKN---------------------------------------------------------------------------------------------------------FAKGSEE----------------------------------------QGRALMNLQNNEAGRRAVYKMADVSCKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRITRQGKLELTNSRFNQPSPEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGTDGCELMCCGRGYDRFKSVQVERCHCRFHWCCFVRCKKCTEIVDQYVCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22726-1", "uniprot_id": "WNT5B_MOUSE", "id": "P22726-1", "name": "Protein Wnt-5b", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSLLLVVVAALLSSWAQLLTDANSWWSLALN-PVQRPEMFIIGAQ--------------------------------------PVCSQLPGLSPGQRKLCQLYQEHMSYIGEGAKTGIRECQHQFRQRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKN---------------------------------------------------------------------------------------------------------FAKGSEE----------------------------------------QGRALMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRITRQGKLELANSRFNQPTPEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDRFKSVQVERCHCRFHWCCFVRCKKCTEVVDQYVCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1J7-1", "uniprot_id": "WNT5B_HUMAN", "id": "Q9H1J7-1", "name": "Protein Wnt-5b", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSLLLLFTAALLSSWAQLLTDANSWWSLALN-PVQRPEMFIIGAQ--------------------------------------PVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKN---------------------------------------------------------------------------------------------------------FAKGSEE----------------------------------------QGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92050-1", "uniprot_id": "WNT5B_DANRE", "id": "Q92050-1", "name": "Protein Wnt-5b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDVRMNQGHLLLAVTLIVCNSQLLVVANSWWSLAMN-PIQRPEMYIIGAQ--------------------------------------PLCSQLTGLSQGQRKLCQLYQDHMVYIGEGAKTGIKECQYQFRQRRWNCSTVDNTSVFGRVMHIGSRETAFTYAVSAAGVVNAVSRACREGELSTCGCSRAARPRDLPRDWLWGGCGDNVNYGYRFAREFVDAREREKN---------------------------------------------------------------------------------------------------------YPRGSVE----------------------------------------HARTLMNLQNNEAGRMAVYNLANVACKCHGVSGSCSLKTCWLQLADFRRVGEFLKEKYDSAAAMRINRRGKLELVNNRFNPPTGEDLVYIDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTYKHERCHCKFHWCCYVKCKRCTSLVDQFVCK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U0B6-1", "uniprot_id": "A0AB32U0B6_DANRE", "id": "A0AB32U0B6-1", "name": "Protein Wnt", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVFLQVMMLLKLKWTSSGVKDTPHTLLFIIITFCVFFMLEIVDANSWWSLAMN-PLLIPEVYVIGGQ--------------------------------------PLCSQLSGLSKGQKKLCQLYQDHMQYIGEGAKTGIRECQHQFRHHRWNCSTVDNSTVLGRVMHIGSRESAFAFAISAAGVLHAVSRACREGALSSCGCSRASRPKDLPRDWLWGGCGDNLNYGYRFSREFVDAREREKT---------------------------------------------------------------------------------------------------------FSKGSAE----------------------------------------SARQMMNLHNNEAGRRIVSDLADVSCKCHGVSGSCSLKTCWLQLADFRKVGDVLKEKYDSAAAMRMNGRGKLVQMHSKFSPPSGQDLLYLQPSPDYCIRNSSSGSLGTQGRLCNKTSEGMDGCALMCCGRGYDQYKAELVERCHCKFHWCCYVRCKRCSSIVDQYVCK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28466-1", "uniprot_id": "WNT5_DROME", "id": "P28466-1", "name": "Protein Wnt-5", "aln": "MSCYRKRHFLLWLLRAVCMLHLTARGAYATVGLQGVPTWIYLGLKSPFIEFGNQVEQLANSSIPLNMTKDEQANMHQEGLRKLGTFIKPVDLRDSETGFVKADLTKRLVFDRPNNITSRPIHPIQEEMDQKQIILLDEDTDENGLPASLTDEDRKFIVPMALKNISPDPRWAATTPSPSALQPNAKAISTIVPSPLAQVEGDPTSNIDDLKKHILFLHNMTKTNSNFESKFVKFPSLQKDKAKTSGAGGSPPNPKRPQRPIHQYSAPIAPPTPKVPAPDGGGVGGAAYNPGEQPIGGYYQNEELANNQSLLKPTDTDSHPAAGGSSHGQKNPSEPQVILLNETLSTETSIEADRSPSINQPKAGSPARTTKRPPCLRNPESPKCIRQRRREEQQRQRERDEWFRGQSQYMQPRFEPIIQTINNTKRFAVSIEIPDSFKVSSEGSDGELLSRVERSQPSISSSSSSSSSSSRKIMPDYIKVSMENNTSVTDYFKHDVVMTSADVASDREFLIKNMEEHGGAGSANSHHNDTTPTADAYSETIDLNPNNCYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAPEMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRGRLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHTCK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : :: : .. : . : * . *** .*:* * : . * *..**::.*:***.**:::******.:: :*:* : :.: * ** .*::** * ::****:* *::*.*** :**::* ** *******:::.*:*: :*:*:**:* . :*. : .* :***:****** * . * ::************ *** **:.:*.:*: *:***:.*: :::. :*:* . :*. *: .**:*:: ***:* .. : **:**:*:*.*.* :.* ::******: : ***:*:***** *:*: *:.::::. **", "identical_positions": 139, "similar_positions": 116, "identity": "13.84%" }, { "cls_id": "homologset.agr.FB:FBgn0010197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23897-1", "uniprot_id": "GUC2C_RAT", "id": "P23897-1", "name": "Guanylyl cyclase C", "aln": "-MTSLLGLAVRLLLFQPTLM-FWASQVRQKCHNGTYEISVLMMDNSAYKEPLQNLRDAVEEGLDIVRKRLREAELNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDRKMG--CVLMGPSCTYSTFQMY---LDTELNYPMISAG---SFGLSCDYKETLTRILPPARKLMYFLVDFWKVNNAPFKTFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLSFKDVLRRSEQFQEILMGRNRKSNVIVMCGTPETFYNVK-GDLKV-----ADDTVVILVDLFSNHYFEDDTRAPEYMDNVLVLT----------------------LPPEKFIANASVSGRFPSERSDFSLAYLEGTLLFGHMLQTFLENG----ESVTTPKFARAFRNLTFQGLEGPVTLDDSGD--IDNIMCLLYVSLDTRKYKVLMAYDTHKNQ-------------TIPVATSPNFIWKNHRLPNDVPGLGPQ------------------ILMIAVFTLTGIVVVLLLIALLVLRKYRRDHELRQKKWSHIPSENIFPLETNETNHVSLKID--------------------DDRRRDTIQRVRQCKYDKKKVILKDLKHCDGNFSEK--QKIELNKLLQSDYYNLTKFYGTVKLDTRIFGVVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSSKIEVHGRLKSTNCVVDSRMVVKITDFGCNSILP-------------PKKDLWTAPEHLRQA----TISQKGDVYSFSIIAQEIILRKET-FYTLSCRDQNEKIFRVENSYGTKPFRPDLFLETADEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLVVKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVETIGDAYVVASGLPMRNGNRHAVDISKMALDILSFMGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTIAILRRTDCQFLYEVRGETYLKGRGTETTYWLTGMKDQEYNLPTPPTVENQQRLQTEFSDMIVSALQKRQASGVKSRRPTR--------VASYKKGFLEYMQLNNSDHDSTYF----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UWA6-1", "uniprot_id": "GUC2C_MOUSE", "id": "Q3UWA6-1", "name": "Guanylyl cyclase C", "aln": "-MTSLLGLAVRLLLFQPALMVFWASQVRQNCRNGSYEISVLMMDNSAYKEPMQNLREAVEEGLDIVRKRLREADLNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDHKMG--CALMGPSCTYSTFQMY---LDTELNYPMISAG---SYGLSCDYKETLTRILPPARKLMYFLVDFWKVNNASFKPFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLNFKDVLRRSEQFQEILTGHNRKSNVIVMCGTPESFYDVK-GDLQV-----AEDTVVILVDLFSNHYFEENTTAPEYMDNVLVLT----------------------LPSEQSTSNTSVAERFSSGRSDFSLAYLEGTLLFGHMLQTFLENG----ENVTGPKFARAFRNLTFQGFAGPVTLDDSGD--IDNIMSLLYVSLDTRKYKVLMKYDTHKNK-------------TIPVAENPNFIWKNHKLPNDVPGLGPQ------------------ILMIAVFTLTGILVVLLLIALLVLRKYRRDHALRQKKWSHIPSENIFPLETNETNHISLKID--------------------DDRRRDTIQRVRQCKYDKKKVILKDLKHSDGNFSEK--QKIDLNKLLQSDYYNLTKFYGTVKLDTRIFGVVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSSKIEVHGRLKSTNCVVDSRMVVKITDFGCNSILP-------------PKKDLWTAPEHLRQA----TISQKGDVYSFAIIAQEIILRKET-FYTLSCRDHNEKIFRVENSYG-KPFRPDLFLETADEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLVVKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVETIGDAYVVASGLPMRNGNRHAVDISKMALDILSFIGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTITILKRTDCQFLYEVRGETYLKGRGTETTYWLTGMKDQEYNLPSPPTVENQQRLQTEFSDMIVSALQKRQASGKKSRRPTR--------VASYKKGFLEYMQLNNSDHDSTYF----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25092-1", "uniprot_id": "GUC2C_HUMAN", "id": "P25092-1", "name": "Guanylyl cyclase C", "aln": "MKTLLLDLALWSLLFQPGWL-SFSSQVSQNCHNGSYEISVLMMGNSAFAEPLKNLEDAVNEGLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTCEGLDLLRKISNAQRMG--CVLIGPSCTYSTFQMY---LDTELSYPMISAG---SFGLSCDYKETLTRLMSPARKLMYFLVNFWKTNDLPFKTYSWSTSYVYKNGTETEDCFWYLNALEASVSYFSHELGFKVVLRQDKEFQDILMDHNRKSNVIIMCGGPEFLYKLK-GDRAV-----AEDIVIILVDLFNDQYFEDNVTAPDYMKNVLVLT----------------------LSPGNSLLNSSFSRNLSPTKRDFALAYLNGILLFGHMLKIFLENG----ENITTPKFAHAFRNLTFEGYDGPVTLDDWGD--VDSTMVLLYTSVDTKKYKVLLTYDTHVNK-------------TYPVDMSPTFTWKNSKLPNDITGRGPQ------------------ILMIAVFTLTGAVVLLLLVALLMLRKYRKDYELRQKKWSHIPPENIFPLETNETNHVSLKID--------------------DDKRRDTIQRLRQCKYDKKRVILKDLKHNDGNFTEK--QKIELNKLLQIDYYNLTKFYGTVKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSILP-------------PKKDLWTAPEHLRQA----NISQKGDVYSYGIIAQEIILRKET-FYTLSCRDRNEKIFRVENSNGMKPFRPDLFLETAEEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTGMKDQKFNLPTPPTVENQQRLQAEFSDMIANSLQKRQAAGIRSQKPRR--------VASYKKGTLEYLQLNTTDKESTYF----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Z2-1", "uniprot_id": "A0ACD6B6Z2_DANRE", "id": "A0ACD6B6Z2-1", "name": "Guanylate cyclase", "aln": "-----MDYRIWLFVCFSWAFLKQSLLMKESCLNGTLLINVVLLDDDVSPWSINFVKPAVMRAVESDSEINFKDGVNLSV--SFRGFQTIYYQKTGCSSSACEGVEILNDLANAGEEG--CALLGPTCTYATFQMADLEIGLNLNMPIISAG---SFGLSCDLKRDLTRLLPPARKISSFFINFWKFHDP--VKPKWETAYLYKKPDNTEDCFWYINALEVSNGGFSPSLQEIEVIRNKEDLTKAMAKHNRESNLFILCGTPDDIMDLKNGTTDY-----DSEIAFLLIDLYNDIYYKGQSNT--FMRNVLVLT----------------------MPN---TRKYTIDTSGNNTMNDYIAAYHDAVLLFGQVMRNIQKSGSLDIQDMESVSMN-YFRNVSFTGIAGEYQLDQHGD--RDLMFSLIYTNNNN-QYNILYQFNTSNNK-------------TGLKDSSPSFIWQS-RLPNDSPSKGLS------------------VIEIIVIVLCTVIGIMGTLAFIFYWQNRYYHHM-QKRWSHISSQLITPLELNEWNMISLKIE--------------------EDSTENSTYILRRARYDKKIVILKEFRLTDGSFTEK--QRIELNTLLKIDYCNLTKFYGTVKFDNEYFGVFEYGERGSLRYVLDDKISYPEETFMDWQFKISVMYDIAKGMSYLHTSNIAVHGRLKSTNCVVDNRMVVKIADFGFNTIVS-------------PSEDLWTAPEHLRKP----GISQKGDVYSFAIISQEIMMRKCT-FYTNTCSDRAEKLARVQYPSTTSFFRPDLNFESTSESEEEVCMLIRNCWDEDPDRRPDFKKIEIALWKIVSR-DNQEHESYMENLIRRLQMYSRNLERLVEERTALYKAERDRADCLNFMLLPGPVVRSLKETGKVEPELFDEVTIYFSDIVGFTTLCHFSTPMEVVDMLNDIYKNFDSILDNHDVYKVETIGDAYMVVSGLPRRNGNRHAKDICLMALDILAFMGTIQLSHLPGIPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSQSTINILQRTDCKFEYEERGETFLKGKGKEMTYWLTGVTGENYNLPTPPTAENFQNLQQDLSEMIKTCLQKRPSGLWRRKTLSARHRKLMVGVEMETTDQPEYLHLATGDFLSTYL----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6TL19-1", "uniprot_id": "GUC2G_MOUSE", "id": "Q6TL19-1", "name": "Guanylate cyclase 2G", "aln": "----MASRTRSESPLEPRLYAGAGSRADHPSLVLMLSVVMLVTCLEAAKLTVGFHAPWNISHPFSVQRLGAGLQTVVDKLNSEPVGLGNVSWEFTYTNSTCSAKESLAVFIDQVQKEHISALFGPACPEAAEVIG--LLASEWNIPLFDFVGQMAALKDHFWCDTCVTLVPPKQEISAVLRESLRYLGWEHIGVFGGSSADSSWEQVDEMWGAVEDGLQFH---FNITASMRYNSSSSDLLQEGLRNMSYVARVIILICSSEDARRILQAAVDLGLD--TGEFVFILLQQLEDSFWKEVLTKDKVIRFPKVYESVFLIAPSAYGGGIGDDGFRKQVSQELRRPPFQSSITSEDQVSPYSAYLHDALLLYAQTVEEMRKAEK-DFRDGRQLISTLRAGQVTLQGITGPVLLDSQGKRHVDYSVYALQESGNRSLFLPFLHYDSFQKV-------------IRPWRNDSNTSWPHGSLPEYKPGCGFHNDLCKTKPPTVAGMTVTVTAVIPTVTFLVLASAAAITGLMLWRLRGKVQSHPGDTWWQIRYDSITLLPQHKLSHRGTPVSRRNVSDTSTVKASADCGSLVKRHQDEELFFAPVGLYQGNQVALCYIGDEAEAWVKKPTVRREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRN-----SDHEIDWIFKLSFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGLWEFKHGSTWRSYNQEATDHSELYWTAPELLRLRESPCSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIISRIKDPRAPVPLRPSLLEDKGDGR---IVALVRECWDESPELRPIFPSIKKTLREASPR----GHVSILDSMMGKLETYANHLEEVVEERTRELVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTAGALLAAGG-YHLQKRGTISVKGKGEQTTFWLKGKDG--FPVPLPEFTEEEAKVSEIL-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55205-1", "uniprot_id": "GUC2G_RAT", "id": "P55205-1", "name": "Guanylate cyclase 2G", "aln": "----MASRARSEPPLEHRFYGGAESHAGHSSLVLTLFVVMLMTCLEAAKLTVGFHAPWNISHPFSVQRLGAGLQIAVDKLNSEPVGPGNLSWEFTYTNATCNAKESLAAFIDQVQREHISVLIGPACPEAAEVIG--LLASEWDIPLFDFVGQMTALEDHFWCDTCVTLVPPKQEIGTVLRESLQYLGWEYIGVFGGSSAGSSWGEVNELWKAVEDELQLH---FTITARVRYSSGHSDLLQEGLRSMSSVARVIILICSSEDAKHILQAAEDLGLN--SGEFVFLLLQQLEDSFWKEVLAEDKVTRFPKVYESVFLIAPSTYGGSAGDDDFRKQVYQRLRRPPFQSSISSEDQVSPYSAYLHDALLLYAQTVEEMMKAEK-DFRDGRQLISTLRADQVTLQGITGPVLLDAQGKRHMDYSVYALQKSGNGSRFLPFLHYDSFQKV-------------IRPWRDDLNASGPHGSHPEYKPDCGFHEDLCRTKPPTGAGMTASVTAVIPTVTLLVVASAAAITGLMLWRLRGKVQNHPGDTWWQIHYDSITLLPQHKPSHRGTPMSRCNVSNASTVKISADCGSFAKTHQDEELFYAPVGLYQGNHVALCYIGEEAEARIKKPTVLREVWLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLKDVLRN-----SDHEMDWIFKLSFVYDIVNGMLFLHGSPLRSHGNLKPSNCLVDSHMQLKLAGFGLWEFKHGSTCRIYNQEATDHSELYWTAPELLRLRELPWSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIISCIKDPRAPVPLRPSLLEDKGDER---IVALVRACWAESPEQRPAFPSIKKTLREASPR----GRVSILDSMMGKLEMYASHLEEVVEERTCQLVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQTHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMSLHLLSVTTNFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTARALLVAGG-YHLQKRGTISVKGKGEQTTFWLTGKDG--FAVPLPEFTEEEAKVPEIL-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07553-1", "uniprot_id": "GCY3E_DROME", "id": "Q07553-1", "name": "Guanylate cyclase 32E", "aln": "----MPGPCASAAAFSCILVLLLLGCQRSNPLAAGATVSSMRRLTDTINIGFLAEYSQMRVTLGGLPLAIEDVNKNPNLLPGKKLAFKPVDIG---HKMSAYRVKPLRAMTQMREAG-VTAFIGPDESCTTEALL----ASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWG-SDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDDEIYDSNRRVNIMERNYLDPYIRKEK--------------SKSLDKISFRSVIKISMTYPQNPHIRVPIYGLHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFD--VYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRK-----------KLDWRYLVSGPLCALVVVVAIALLIKHYRYEQTLAGLLWKVDMKDVTVINLGEYNNPTNKNIFQICR-----------QSILVVGEPNKRSFTNIALFRGNIVAMKKIHKKSVDITRS--IRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLAN-----EDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQ--EEPNKSELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQHGVFRPALTHTHLDIP-DYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAG----LKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGS-YVCIERGLTSIKGKGDMRTYWLTKRQQPELTPDLISTVDTLDTYCSGPRESMEVSVHQYCSPASNNYRLGSCNCDTKCLYSRRSDDNVTNSHGTSEFPKVSEPAQVNCNQLCVCRLNSSQMFNNRGPRSAPSITFRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .. . . :. . * : . .::** . :: : . *::. . . . :.* :: . . . : . : : *. . : . : :.: :: . . .. : : : . : :. ::: : : . . . :: * :* *. : . : . . : . * . * .. .: . :: . : : : . : : : * : : .. :: : : : *: * *. . . * :***. *: : . :* * *. ** :*: :** * **.*:.:**::*.: :::.** : .. *** ** : :*****:.*: ::: :: : :** * . : : ** *.*: ** : :. * : . . ::.:: :: *: :** :*:*** *: :.: * :** * . * **.* :: *** ******** :* *:*::**.:*** *. * :. :************:*.**** :** :** :*. ::*.:* ::: * * : :***:*:** .***** .************ ******:. .:***:* :* * : ** :**:* *:**. .: ", "identical_positions": 164, "similar_positions": 216, "identity": "13.34%" }, { "cls_id": "homologset.agr.FB:FBgn0010198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0W1-1", "uniprot_id": "RS22A_YEAST", "id": "P0C0W1-1", "name": "Small ribosomal subunit protein uS8A", "aln": "-----------------------------------MTRSSVLADALNA---------------------INNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFEYIDDHR-------SGKIVVQLNGRLNKCGVISP--RFNVKIGDIEKWTANLLPARQ---FGYVILTTSAGIMDHEEARRKHVSGKILGFVY---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3E7Y3-1", "uniprot_id": "RS22B_YEAST", "id": "Q3E7Y3-1", "name": "Small ribosomal subunit protein uS8B", "aln": "-----------------------------------MTRSSVLADALNA---------------------INNAEKTGKRQVLLRPSSKVIIKFLQVMQKHGYIGEFEYIDDHR-------SGKIVVQLNGRLNKCGVISP--RFNVKIGDIEKWTANLLPARQ---FGYVILTTSAGIMDHEEARRKHVSGKILGFVY---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P62245-1", "uniprot_id": "RS15A_MOUSE", "id": "P62245-1", "name": "Small ribosomal subunit protein uS8", "aln": "-----------------------------------MVRMNVLADALKS---------------------INNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHR-------AGKIVVNLTGRLNKCGVISP--RFDVQLKDLEKWQNNLLPSRQ---FGFIVLTTSAGIMDHEEARRKHTGGKILGFFF---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62246-1", "uniprot_id": "RS15A_RAT", "id": "P62246-1", "name": "Small ribosomal subunit protein uS8", "aln": "-----------------------------------MVRMNVLADALKS---------------------INNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHR-------AGKIVVNLTGRLNKCGVISP--RFDVQLKDLEKWQNNLLPSRQ---FGFIVLTTSAGIMDHEEARRKHTGGKILGFFF---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62244-1", "uniprot_id": "RS15A_HUMAN", "id": "P62244-1", "name": "Small ribosomal subunit protein uS8", "aln": "-----------------------------------MVRMNVLADALKS---------------------INNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHR-------AGKIVVNLTGRLNKCGVISP--RFDVQLKDLEKWQNNLLPSRQ---FGFIVLTTSAGIMDHEEARRKHTGGKILGFFF---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K6I0-1", "uniprot_id": "A0A0G2K6I0_RAT", "id": "A0A0G2K6I0-1", "name": "Small ribosomal subunit protein uS8", "aln": "--------------------------------------MNVLADALKS---------------------INNVENRGKCQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHR-------AGNIVVNLTGRLNKCGVISP--RFDVQLKDLEKWQNNLLPSRQ---FGFIVLTTSAGIMDHEEARRKHTGGKILGFFF---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q420-1", "uniprot_id": "RS15A_DANRE", "id": "Q6Q420-1", "name": "Small ribosomal subunit protein uS8", "aln": "-----------------------------------MVRMNVLADALKS---------------------INNAEKRGKRQVLLRPCSKVIVRFLTVMMKHGYIGEFEIIDDHR-------AGKIVVNLTGRLNKCGVISP--RFDVQLKDLEKWQNNLLPSRQ---FGFIVLTTSAGIMDHEEARRKHTGGKILGFFF---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48149-1", "uniprot_id": "RS15A_DROME", "id": "P48149-1", "name": "Small ribosomal subunit protein uS8A", "aln": "-----------------------------------MVRMNVLADALKC---------------------INNAEKRGKRQVLLRPCSKVIIKFLTVMMKHGYIGEFEIVDDHR-------SGKIVVNLTGRLNKCGVISP--RFDVPINDIEKWTNNLLPSRQ---FGYVVLTTSGGIMDHEEARRKHLGGKILGFFF---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4A2Q0-1", "uniprot_id": "FND10_RAT", "id": "D4A2Q0-1", "name": "Fibronectin type III domain-containing protein 10", "aln": "MRAPPLLLLLAACAPPSGAAVDPTPPGWEPAPDAPWCPYKVLSEGPEAGGGRLCFRSPVRGFRCQTPGCVTLASAGGSLRAHVLRNRSVLLQWRLAPAEARRVRVFALNCSWRGTYTRFPCDRVLLGASCRDYLLPDVHDSVRYRLCLQPLPLPLRAELAAAPPELAECVEFTAEPAAMQEIVVAMTAVGGSICVMLVVICLLVAYITENLMHPTFRRPSLRRQP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**::. :. :. .. *. :. : .*:::: . : : * . * ...::: . * : *: : : : *.: : :*:. . *:. . . .*.* :. ", "identical_positions": 13, "similar_positions": 50, "identity": "5.78%" }, { "cls_id": "homologset.agr.FB:FBgn0010213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07895-1", "uniprot_id": "SODM_RAT", "id": "P07895-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MLCRAACSAGRRLG--PAASTAGSRHKHSLPDLPYDYGALEPHINAQIMQLHHSKHHATYVNNLNVTEEKYHEA---LAK----GDVTTQVALQPALKFNGGGHINHSIFWTNLSP---KGGGEPKGELLEAIKRDFGSFEKFKEKLTAVSVGVQGSGWGWLGFNKEQG-RLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVSQRYIVCKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09671-1", "uniprot_id": "SODM_MOUSE", "id": "P09671-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MLCRAACSTGRRLG--PVAGAAGSRHKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNATEEKYHEA---LAK----GDVTTQVALQPALKFNGGGHINHTIFWTNLSP---KGGGEPKGELLEAIKRDFGSFEKFKEKLTAVSVGVQGSGWGWLGFNKEQG-RLQIAACSNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYTACKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04179-1", "uniprot_id": "SODM_HUMAN", "id": "P04179-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MLSRAVCGTSRQLA--PVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEA---LAK----GDVTAQIALQPALKFNGGGHINHSIFWTNLSP---NGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERG-HLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00637-1", "uniprot_id": "SODM_DROME", "id": "Q00637-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "------MFVARKIS--QTAS-LAVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEA---KSK----SDTTKLIQLAPALRFNGGGHINHTIFWQNLSP---NK-TQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGWLGFNKKSG-KLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDISCRFQEAKKLGC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00447-1", "uniprot_id": "SODM_YEAST", "id": "P00447-1", "name": "Superoxide dismutase [Mn], mitochondrial", "aln": "MFAKTAAANLTKKGGLSLLSTTARRTKVTLPDLKWDFGALEPYISGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAKEPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQTYNQDTVTGP--LVPLVAIDAWEHAYYLQYQNKKADYFKAIWNVVNWKEASRRFDAGKI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . * * :**.* :*:.**** * :* :**: *** :***.:*.: :: .* :* .:. : : ::*:***. ** :** **:* *.. * :**. :: *:::: : .: ..******.:: * . * :*::. ***.: .. *:**..**.*********:* :..*.:***:: **.: : *: * ", "identical_positions": 74, "similar_positions": 75, "identity": "31.09%" }, { "cls_id": "homologset.agr.FB:FBgn0010215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYF7-1", "uniprot_id": "A0A0G2JYF7_RAT", "id": "A0A0G2JYF7-1", "name": "Catenin alpha-2", "aln": "-----------------MTSATSP-IILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISSAAQATSPTDEAKGHTGIG-ELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQED---YDVRSRTSVQTEDD------QLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTGVQSTFTTFYEVDCDVIDGGRASQLSTHLPTCAEGAPIGSGSSDSSMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQT-RVRRGSQKKHISPVQALSEFKAMDSF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61301-1", "uniprot_id": "CTNA2_MOUSE", "id": "Q61301-1", "name": "Catenin alpha-2", "aln": "-----------------MTSATSP-IILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISSAAQATSPTDEAKGHTGIG-ELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQED---YDVRSRTSVQTEDD------QLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTGVQSTFTTFYEVDCDVIDGGRASQLSTHLPTCAEGAPIGSGSSDSSMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQT-RVRRGSQKKHISPVQALSEFKAMDSF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26232-1", "uniprot_id": "CTNA2_HUMAN", "id": "P26232-1", "name": "Catenin alpha-2", "aln": "-----------------MTSATSP-IILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIG-ELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQED---YDVRSRTSVQTEDD------QLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTGVQSTFTTFYEVDCDVIDGGRASQLSTHLPTCAEGAPIGSGSSDSSMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQT-RVRRGSQKKHISPVQALSEFKAMDSF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7ZC77-1", "uniprot_id": "CTNA2_DANRE", "id": "B7ZC77-1", "name": "Catenin alpha-2", "aln": "-----------------MTSATSP-ILLKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSSKKKGRSKKAHVLAVSVEQATQNFLEKGEQIAKDSQDLKEELIAAVEDVRKQGDTMRVASSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRLLAHLKI----------------------------------------ELKDPQCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIGGISSSAQATSPTDEKHGHAGIG-ELAAALNEFDNKIILDPLTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNSAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRILTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVVHIINAEMENYEPGVYTERVLESIKLLSETVMPRFAEQVEVAIEALSTSPPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQED---YDARSRTSIQTEDD------QLIAGQSARAIMAQLPQEEKAKIAEQVESFRQEKSKLDAEVAKWDDNGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNSSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSG------------------------------------------------LDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWRMKAPEKKPLVKREKPEECQT-RVRRGSQKKHISPVQALSEFKAMDSF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35221-1", "uniprot_id": "CTNA1_HUMAN", "id": "P35221-1", "name": "Catenin alpha-1", "aln": "-----------------MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDD-SDFETED---FDVRSRTSVQTEDD------QLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSG------------------------------------------------VDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQT-KIKRASQKKHVNPVQALSEFKAMDSI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26231-1", "uniprot_id": "CTNA1_MOUSE", "id": "P26231-1", "name": "Catenin alpha-1", "aln": "-----------------MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEELVVAVEDVRKQGDLMKSAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGNRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDAAQHQGGSGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDD-SDFETED---FDVRSRTSVQTEDD------QLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSG------------------------------------------------VDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQT-KIKRASQKKHVNPVQALSEFKAMDSI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PVF8-1", "uniprot_id": "CTNA1_DANRE", "id": "Q9PVF8-1", "name": "Catenin alpha-1", "aln": "-----------------MTSINTANINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNSSNKGPSNKKKGRSKKAHVLAASVDEATQNFLEKGEKIAKESQFLKEELTAAVEDVRKQGESMKMASGEFAEDPCSSVKRGNMVRAARALLSAVTHLLVLADMADVYQLLLQLKLVEENLMKVRNAGTEQDLGIQYKALKPEVDKLNMMAAKRQQELKDVHHKDQMAAARGVLQRNVPMLYTASRACLQHPDVAAYKANRDLIYKQLQHAVSGISNAAQATSSEDSSFSQTAGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNSVRQALQDLLSEYMGNAGRKEKSDALNTAIDRMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMAASQLETLCPQVINAALALAAKPNSKVAQDNMDLFKDQWEKQVRVLTDAVDDITSIDDFLCVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVVHVVTSEMDNYMPGVYTEKVLEATKLLTETVMPRFTEQVEAAVEALSANNGQPVDENEFIDASRLVYDGVRDIRKAVLMIRTPEELDD-SDFETED---FDSRSRTSVQTEDD------QLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRAIADQCPDSACKQDLLAYLQRIALFCHQLNICSKVKAEVQNLGGELVVSG------------------------------------------------LDSAMSLIQAAKNLMNSVVSTVKASYVASTKYQKSQDMQSLNMPAISWKMKAPEKKPLVKREKLDDGQTNKVKRSSQKKHINPVQALSEFKAMDSI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35220-1", "uniprot_id": "CTNA_DROME", "id": "P35220-1", "name": "Catenin alpha", "aln": "----------MLKPDKMGTLTDFGQIALKWDPKNLEIRTMSVEKTLEPLVLQVTTLVNT--KGPSKKKKGKSKRASALVAAVEKATENFIQKGEQIAYENPDITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAARNLLSAVTRLLILADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDDLAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFILKQVCDAVNTISDVAQGKSSQ-PTDIYSGAG-ELAAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAALMADADCTRDERRERIVAECNAVRQALQDLLSEYMSNMSQKDNSPGLSRAIDQMCRKTRDLRRQLRKAVVDHVSDSFLETTTPLLDLIEAAKSGNEKKVREKSEIFTKHAEKLVEVANLVCSMSNNEDGVKMVRYAAAQIESLCPQVINAASILTVRPNSKVAQENMTTYRQAWEVQVRILTEAVDDITTIDDFLAVSENHILEDVNKCVMALQVGDARDLRATAGAIQGRSSRVCNVVEAEMDNYEPCIYTKRVLEAVKVLRDQVMMKFDQRVGAAVGALSNNSNKDVDENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEFEPVEDLTLETRSRSSAHTGDQTVDEYPDISGICTAREAMRKMTEEDKQKIAQQVELFRREKLTFDSEVAKWDDTGNDIIFLAKHMCMIMMEMTDFTRGRGPLKTTMDVINAAKKISEAGTKLDKLTREIAEQCPESSTKKDLLAYLQRIALYCHQIQITSKVKADVQNISGELIVSG------------------------------------------------LDSATSLIQAAKNLMNAVVLTVKYSYVASTKYTR---QGTVSSPIVVWKMKAPEKKPLVRPEKPEEVRA-KVRKGSQKKVQNPIHALSEFQSPADAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0G2JX81-1", "uniprot_id": "A0A0G2JX81_RAT", "id": "A0A0G2JX81-1", "name": "", "aln": "MFLRRRPGVEVLSDLWIGNMSAETPITLQMDMQDLQIQTFTVEKLLEPLIIQVTTLVNCP-QNPSNRKKGRSKRARVLLASVEEATWNLLDKGEMIAKEATVLKEDLEAALQEVRKESKALKGSAERFTDDPCYLPKREAVVQAARALLAAVTRLLILADMTDVMCLLQHVSSFQRTFKSLKNVSNKSDLQKTYQKLGKELERLDRFAFKRQQDLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVISNASQGIQNVPASLEPQAAT--LGSALDELENLIVLNPLTVTEEDLRPPLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMSNIGKTERSNTLNTAIVNMSKKTRDLRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGQVKEIKDYASIFHEHTGRLMEVANLACSMSTNEDGIKIVRIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVDDITSIDDFLAVSESHILEDVNRCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNVNLLTSIVIPEFVTQVNVALDALSKNALTALDDNQFVDISKKIYDTIHDIRCSVMIIRTPEELEDVSDLEDDH----EVRSHTSTQTEGK------------TDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVSA------------------------------------------------LDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSSAGPRHPVVMWRMKAPAKKPLIKREKPEETWA-VVRRGSAKKKIHPVQVMSEFRGRQVY-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q65CL1-1", "uniprot_id": "CTNA3_MOUSE", "id": "Q65CL1-1", "name": "Catenin alpha-3", "aln": "-------------------MSAETPITLNMDTQDLQIQTFTVEKLLEPLIIQVTTLVNCP-QNPSNRKKGRSKRARVLLASVEEATWNLLDKGEMIAKEATVLKEELAAALQEVRKESKALKVSAERFTDDPCYLPKREAVVQAARALLAAVTRLLVLADMIDVMCLLQHVSSFQRTFESLKNVSNKSDLQRTYQKLGKELESLDYLAFKRQQDLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVISNASQGIQNAPAPPEPQAAT--LGSAFDELENLIVLNPLTVTEEDVRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLTEYMSNTGKTERSNTLNTAIVNMSKKTRDLRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGRVKEIKDYAAIFHEHTGRLVEVANLACSMSTNEDGIKIVRIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALDALSKNSLTALDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEDDH----EVRSHTSIQTEGK------------TDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVSA------------------------------------------------LDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSSAGPRHPVVMWRMKAPAKKPLIKREKPEETWA-AVRRGSAKKKIHPVQVMSEFRGRQVY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI47-1", "uniprot_id": "CTNA3_HUMAN", "id": "Q9UI47-1", "name": "Catenin alpha-3", "aln": "-------------------MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCP-QNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNASQGIQNMTTPPEPQAAT--LGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEH----EVRSHTSIQTEGK------------TDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSA------------------------------------------------LDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAGPRHPVVMWRMKAPAKKPLIKREKPEETCA-AVRRGSAKKKIHPLQVMSEFRGRQIY-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: * :.*:::*::**: ****: ******* :.** :*:*:**:* .* .:*::** *:::**: ** : :.::: .::::*:* .. : :: .*::*** ** :*:*** **:***:**:**** ** ** : :**. :*::*.**. *:.: .:* : . . :.*.:: :..:* : ::: .*: **. :*. . *. *:::::: *:::*:: :* * **:***:***.***:**:.**** :****:****::********:***.* .:.:.. *. *: .* :************::**:*****:*..*** ******.*. *:::: : :* :*: :*:*****.**:*.**:*:*:*: :* ::::****:**** *: :*:*: .::.* :: ** :::**:******::****.***.*******:*::**: *. * :****:**::** ::: .**:.* . **: *:. :.* . *: .* :* .*: *** . .::*:*:* *: :** :::** :*:: *:.*:*: :::* . : **::* :* .. : * * ::.: :* ***:** *:. * .:*:*: ***..****.***:**************:**** : *** *** *:*:*:::* * * :*::**:.. *:******::* ::.**::* *:***::**:.***::*. :**. ***********:** *** **:**** : * : *:**** ****:: ** :: : :::.* ** *::.:***:. ", "identical_positions": 367, "similar_positions": 293, "identity": "37.33%" }, { "cls_id": "homologset.agr.FB:FBgn0010217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10719-1", "uniprot_id": "ATPB_RAT", "id": "P10719-1", "name": "ATP synthase F(1) complex catalytic subunit beta, mitochondrial", "aln": "-MLSLVGRVASASASGALRGLNPLAALPQAHLLLRTAPAGVHPARDYAAQSSAAPKAGTATGQIVAVIGAVVDVQFDEG-LPPILNALEVQGRESRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGDYDHLPEQAFYMVGPIEEAVAKADKLAEEHGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56480-1", "uniprot_id": "ATPB_MOUSE", "id": "P56480-1", "name": "ATP synthase F(1) complex catalytic subunit beta, mitochondrial", "aln": "-MLSLVGRVASASASGALRGLSPSAALPQAQLLLRAAPAGVHPARDYAAQASAAPKAGTATGRIVAVIGAVVDVQFDEG-LPPILNALEVQGRDSRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGNEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06576-1", "uniprot_id": "ATPB_HUMAN", "id": "P06576-1", "name": "ATP synthase F(1) complex subunit beta, mitochondrial", "aln": "-MLGFVGRVAAAPASGALRRLTPSASLPPAQLLLRAAPTAVHPVRDYAAQTSPSPKAGAATGRIVAVIGAVVDVQFDEG-LPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05825-1", "uniprot_id": "ATPB_DROME", "id": "Q05825-1", "name": "ATP synthase subunit beta, mitochondrial", "aln": "-MFALR------AASKADKNLLPFLG---------------QLSRSHAAKAAKA--AAAANGKIVAVIGAVVDVQFDDN-LPPILNALEVDNRSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVLDTGYPIRIPVGAETLGRIINVIGEPIDERGPIDTDKTAAIHAEAPEFVQMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYNEMIEGGVISLKDKTSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIIGQEHYNVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFQVAEVFTGHAGKLVPLEQTIKGFSAILAGDYDHLPEVAFYMVGPIEEVVEKADRLAKEAA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00830-1", "uniprot_id": "ATPB_YEAST", "id": "P00830-1", "name": "ATP synthase subunit beta, mitochondrial", "aln": "MVLPRLYTATSRAAFKAAKQSAPLLS------------------TSWKRCMASAAQSTPITGKVTAVIGAIVDVHFEQSELPAILNALEIKTPQGKLVLEVAQHLGENTVRTIAMDGTEGLVRGEKVLDTGGPISVPVGRETLGRIINVIGEPIDERGPIKSKLRKPIHADPPSFAEQSTSAEILETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFTGVGERTREGNDLYREMKETGVINLEGE-SKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERITTTKKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDAAVVGQEHYDVASKVQETLQTYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFAVAEVFTGIPGKLVRLKDTVASFKAVLEGKYDNIPEHAFYMVGGIEDVVAKAEKLAAEAN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .* * : * . . : : : . .*::.*****:***:*::. **.******:. . :***********.****************:****:* ** :*** ******:*************.:. .***:.*.* : *.. *** *************:****************:* *****:******:***:*************.** * ***.*:. ******:*******************:******:******************************************** :***********:*****:***************************.*:*************.**::*. ::*.***:** **: ** ******************:***** ************* ******* **** *::*: .*. :* *.**::** ****** **:.* **::** * ", "identical_positions": 365, "similar_positions": 79, "identity": "68.74%" }, { "cls_id": "homologset.agr.FB:FBgn0010220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTF0-1", "uniprot_id": "E9PTF0_RAT", "id": "E9PTF0-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAELRLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVTQALELSRKPHVVIATPGRLADHLRSS--NTFN-MKKIRFLVLDEADRLLEQGCTDFTADLETILSAVPAR--RQTLLFSATLTDTLKELQGLATN--QP----FFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALARFKSSTYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLLHAIEEEIKQQLAEL--AVEEAQVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPD------------------------LEAKRKAELAKIKQQNRRFKEKVEQTLRQQKAGSTGRRSRPPRPRP-QEPARAEAQN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4FZF3-1", "uniprot_id": "DDX49_MOUSE", "id": "Q4FZF3-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAEIGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS--NTFN-MKKIQFLVMDEADRLLEQGCTDFTTDLETILAAVPAR--RQTLLFSATLTDTLKELQGLATN--EP----FFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLLHAIEEQIKQQLAEL--VVEEAEVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPD------------------------LEAKRKAELAKIKQQNRRFKEKVGQTLRRQKAGSTVRRSRPPRSRP-QEPAQAEAQD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6V7-1", "uniprot_id": "DDX49_HUMAN", "id": "Q9Y6V7-1", "name": "Probable ATP-dependent RNA helicase DDX49", "aln": "-----MAGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS--NTFS-IKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR--RQTLLFSATLTDTLRELQGLATN--QP----FFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-YDIHLVHAIEEQIKKKLEEF--SVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDPD------------------------LEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRTPSGSHSGPVPSQGLV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38719-1", "uniprot_id": "DBP8_YEAST", "id": "P38719-1", "name": "ATP-dependent RNA helicase DBP8", "aln": "-----MADFKSLGLSKWLTESLRAMKITQPTAIQKACIPKILEGRDCIGGAKTGSGKTIAFAGPMLTKWSEDPSGMFGVVLTPTRELAMQIAEQFTALGSSMNIRVSVIVGGESIVQQALDLQRKPHFIIATPGRLAHHIMSSGDDTVGGLMRAKYLVLDEADILLTS---TFADHLATCISALPPKDKRQTLLFTATITDQVKSLQNAPVQKGKPPLFAYQVESVDNVAIPSTLKIEYILVPEHVKEAYLYQLLT--CEEYENKTAIIFVNRTMTAEILRRTLKQLEVRVASLHSQMPQQERTNSLHRFRANAARILIATDVASRGLDIPTVELVVNYDIPSDPDVFIHRSGRTARAGRIGDAISFVTQ-RDVSRIQAIEDRINKKMTETNKVHDTAVIRKALTKVTKAKRESLMAMQKENFGERKRQQKKK---------------------------------------------------------------QNDGKSLRS-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07886-1", "uniprot_id": "DDX49_DROME", "id": "Q07886-1", "name": "Probable ATP-dependent RNA helicase Dbp45A", "aln": "MQRKEANPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLADHLTGC--DTFS-FDNLKYLVVDEADRMLNG---DFDESLSIIERCLPKT--RQNLFFSATMKDFIKESSIFPIAS-----DCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEH--PIDQRMVERIFMQVNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKLREIRRKRKLQHAEPAASEEGKALLQDERFKSVDSARFEKKGKGRSRATQEDTPTKPLKRLNKEKPVAQKGRADVKKDKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * **.:. : :. .*.:* *** ** *:**:* ******** **. *:* : **:* . * :*****:*** **:*** . *..:.:: .:: ** . : :: .* ::**.::* *****.*: .. :*.. : . ::**:**** :* * * .:* **.*:*:**:.* ::. . . : . * . *. .*:* .: :: * . : :: *: . :**.* .::* *:::.. ..**. * *:** :* :*::. * *******:******:*::*:*: * *. :*** ******** * :*::. *: : ***:.*: :: * : : : : :*. .:**. : :: .*.*: . ::* : * : ", "identical_positions": 139, "similar_positions": 139, "identity": "25.93%" }, { "cls_id": "homologset.agr.FB:FBgn0010222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18155-1", "uniprot_id": "MTDC_MOUSE", "id": "P18155-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "-MASVSLLSALAVRL-------------LRPTHGCHPRLQP-FHLAAVRNEAVVISGRKLAQQIKQEVQQEVEEWVASGNKR-PHLSVILVGDNPASHSYVLNKTRAAAEVG--------------------------------------------INSETIVKPASVSEEELLNSIRKLNNDENVDGLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQ---------YSMLPATPWGVWEIIKRTGIPT---------LGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN--RVQDPVTAKPKLVGDVDFEGVKKKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRP-EELEVFKSKQRGVATN------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GID3-1", "uniprot_id": "A0A8I6GID3_RAT", "id": "A0A8I6GID3-1", "name": "methenyltetrahydrofolate cyclohydrolase", "aln": "-MVSVS-LSALAVRL-------------LRPTHGCHSRLQS-FHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKR-PHLSVILVGDNPASHSYVLNKTRAAAEVAGSWIGHSSQLRQKGRKTPGARPLTVTRADAGTSKPAASRLMSYGINSETIVKPASVSEEELLNSIRTLNDDENVDGLLVQLPLPEHIDERKICNAVSPDKDVDGFHVINVGRMCLDQ---------YSMLPATPWGVWEILKRTGIPT---------LGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRHTPKEQLKKHTILADIVISAAGIPNLITADMIKEGATVIDVGIN--RVQDPVTAKPKLVGDVDFEGVKKKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRP-EELEVLKSTQRGVATN------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13995-1", "uniprot_id": "MTDC_HUMAN", "id": "P13995-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "-MAATSLMSALAARL-------------LQPAHSCSLRLRP-FHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKR-PHLSVILVGENPASHSYVLNKTRAAAVVG--------------------------------------------INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQ---------YSMLPATPWGVWEIIKRTGIPT---------LGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN--RVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRL-EEREVLKSKELGVATN------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YZG8-1", "uniprot_id": "MTD2L_MOUSE", "id": "D3YZG8-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MATRARGFSLLRGRLGRGP---------VRAPGVAERAWRG-FGSSGRRHEAVIISGTNMAKQIQKEIQQGVESWIALGNRR-PHLSIILVGDNPASHTYVRNKIKAASAVG--------------------------------------------ICSELIIKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRAGIET---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPREQLKAHTQLADIIIVAAGIPRLITADMVREGAAVIDVGIN--YIQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNIAY------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUA0-1", "uniprot_id": "MTD2L_RAT", "id": "D3ZUA0-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MATRARGLSLLRGRLGRGP---------ARAPGVAERAWRG-FGSSSRRHEAVIISGTEMAKQIRRELQQGVESWLALGNRR-PHLSIILVGDNPASHTYVRNKIRAASAVG--------------------------------------------ICSELIVKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRAGIET---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRHTPREQLKAHTQLAEIIIVAAGIPGLITADMVREGATVIDVGIN--YVQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNITY------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H903-4", "uniprot_id": "MTD2L_HUMAN", "id": "Q9H903-4", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial", "aln": "MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRG-FRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRR-PHLSIILVGDNPASHTYVRNKIRAASAVG--------------------------------------------ICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQ---------HSLIPATASAVWEIIKRTGIQT---------FGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGIN--YVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEG5-1", "uniprot_id": "A0A8M2BEG5_DANRE", "id": "A0A8M2BEG5-1", "name": "methenyltetrahydrofolate cyclohydrolase", "aln": "MAAPG-ALTVNYTRIQTLMSCFTYCRRPKRWINLKTVNRRSSFCQSLKRHVATVVSGAELARQIHKEVQSDIAKLVAEGNRR-PHLSVILVGDDHASHTYVRNKTRTASLLG--------------------------------------------MSSSTIFRPSSVSQEEMLELIDKFNRDRNISGLLVQLPLPEHINERAICNAVAPEKDVDGFHIVNIGKLCLDQ---------RCMIPATAAAVWEIIRRTGLET---------VGKNVLVVGRSKNVGMPIAMLLHSDRKHERSGGDATVIMAHRCTPLPRLKELARLADIVIAAAGVPHLITADMVKEGAAVIDVGIN--RMQDPVTGKSRLVGDVDFEAVKEKAGFITPVPGGVGPMTIAMLQANTLVTEEKKIVEWAETRLCLLLASGSGSDAGHYTGMAKKDWIHWSSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04448-1", "uniprot_id": "MTDC_DROME", "id": "Q04448-1", "name": "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "aln": "--------------------------------------------MRFTSNMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPK-PHLTAVIVGEDPASEKYVANKMVACREVG--------------------------------------------ISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGRTALDM---------EANIPATPLGVKRLLEHMKIET---------LGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVTICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGIN--RIKDESTGQFKLVGDVDFEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARKQFDDRKSS-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02046-1", "uniprot_id": "MTD1_YEAST", "id": "Q02046-1", "name": "Methylenetetrahydrofolate dehydrogenase [NAD(+)]", "aln": "-----------------------------------------------MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMG--------------------------------------------FRYDLRVIE---DKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTG---KVTIAMLLRNMLRLVRNVELSKEK--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :*. .. :: : : * * .:..:: *:. *. . :. :. : . :: : : * * : *::* :*: : ::: : : : :***:*:: : . : . :*.*. .: .::. : . *:: :* .**: *. *:* ** * .: * . : *:: *. : : ::: . . : *:: *. .*:.* :*:*** * : .: ", "identical_positions": 38, "similar_positions": 96, "identity": "8.46%" }, { "cls_id": "homologset.agr.FB:FBgn0010223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BHS4-1", "uniprot_id": "A0A8M2BHS4_DANRE", "id": "A0A8M2BHS4-1", "name": "Guanine nucleotide-binding protein subunit alpha", "aln": "-----MGCWRWCYTTCICCLSE-EDKNAIVIHNEIKRILAEQKKRERREIKVLLLGTGESGKTTFIKQMRIIHGKGFSEEDRRGYIKNVYQNIFTAMRAMTGAMESLRIPYANPQNEAYGRQFKDVEIRQVTQLDRMYVEAIRRLWADPGIKACYCRRREYQLLDSTEYYMTNLDRITAPDYIPTAQDVLRVRFPTTGINDYSFSVEKIT--------LRIVDVGGQKSERRKWIHCFENVTSLIFLASLSEYDQVLEENSKENRMKESLSLFYTTIHSPWFASASIILFLNKMDILEEKIQS-SDLKAYFPEFQGKKRDKNDAKTYISS-----------------LYRKEASNRESG--MHRGFYMHFTCATDTNNIRKVFMDVKETILTNELQSIGML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05337-1", "uniprot_id": "GNAF_DROME", "id": "Q05337-1", "name": "Guanine nucleotide-binding protein G(f) subunit alpha", "aln": "MKLRLLRCLRQQPAKPAAVMTHKEDQYPVSLDHHVLKDMAKGVR--DTTVKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSCTSERSADYILSLPGSAPEYMNEEYCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGISQITFRVPIPKSMGGGEQQFQMYDVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRAGKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQEPFKRHSRNQVDLGTSERECYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :. . ::. **: .: :.:.: : :*: : :*:*****.******:******:* :**::::** * ::****. :: :.* * * * :.. .* . : .: ::. * : : ** * **:*** * .*: ****::*:: *: **: .:***:::*:*: * ****.: :* * . ::: *****:.:*.***: **.: :::** * **:** *.*:..:**::*:*.** :. :. ::***.:*:**** **:*.**:: ..: ****::. : :: : : .* :::.: *: . .* * *** ****. **.** **:: **::::.*:*::", "identical_positions": 133, "similar_positions": 137, "identity": "33.17%" }, { "cls_id": "homologset.agr.FB:FBgn0010225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09327-1", "uniprot_id": "VILI_HUMAN", "id": "P09327-1", "name": "Villin-1", "aln": "-------------------------------------------------------MTKLSAQVKGSLNIT---------------------------TPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIH--KTASSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKR-RELKAAVPDTVVEPAL-KAALKLYHVSDSEGNLVVREVATR-PLTQDLLSHEDCYILDQG-GLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSG--LGKTHTVGSVAKVEQVKFDATSMHVKPQ--------VAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGE-KQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQI---------RVPMGKEPPHLMSIFKGR-MVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQ--SCCYLWCGKGCSGDEREMAKM-VADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEE-NLVITPRLFECSNKTGRFLATEIP-DFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRDPETP-IIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSRDWSQITAEVTSPKVD------------------VFNANSNLSSGPLP-----------IFPLEQLVNKPVEELPEGVDPSRKEEHLSIEDFTQAFGMTPAAFSALPRWKQQNLKKEKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62468-1", "uniprot_id": "VILI_MOUSE", "id": "Q62468-1", "name": "Villin-1", "aln": "-------------------------------------------------------MTKLNAQVKGSLNIT---------------------------TPGIQIWRIEAMQMVPVPSSTFGSFFDGDCYVVLAIH--KTSSTLSYDIHYWIGQDSSQDEQGAAAIYTTQMDDYLKGRAVQHREVQGNESETFRSYFKQGLVIRKGGVASGMKHVETNSCDVQRLLHVKGKRNVLAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESNRMERLRGMALAKEIRDQERGGRTYVGVVDGEKEGDSPQLMAIMNHVLGPR-KELKAAISDSVVEPAA-KAALKLYHVSDSEGKLVVREVATR-PLTQDLLKHEDCYILDQG-GLKIFVWKGKNANAQERSGAMSQALNFIKAKQYPPSTQVEVQNDGAESPIFQQLFQKWTVPNRTSG--LGKTHTVGSVAKVEQVKFDALTMHVQPQ--------VAAQQKMVDDGSGEVQVWRIEDLELVPVESKWLGHFYGGDCYLLLYTYLIGE-KQHYLLYIWQGSQASQDEIAASAYQAVLLDQKYNDEPVQI---------RVTMGKEPPHLMSIFKGR-MVVYQGGTSRKNNLEPVPSTRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKTP--SCCYLWCGKGCSGDEREMAKM-VADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEE-NQVITPRLFECSNQTGRFLATEIF-DFNQDDLEEEDVFLLDVWDQVFFWIGKHANEEEKKAAATTVQEYLKTHPGNRDLETP-IIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYDDLKAELGNSGDWSQIADEVMSPKVD------------------VFTANTSLSSGPLP-----------TFPLEQLVNKSVEDLPEGVDPSRKEEHLSTEDFTRALGMTPAAFSALPRWKQQNIKKEKGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QVU3-1", "uniprot_id": "F1QVU3_DANRE", "id": "F1QVU3-1", "name": "Villin-1", "aln": "------------------------------------------------------MPQEVKTDVPKVLNKT---------------------------TPGLQIWRVENMELVPCPSKTFGQFFEGDSYVILYTH--KTSNNFSYDIHYWLGKSTSQDEMGAAAIYTTQMDDHLGGVAVQHRETQGHESATFQGYFKQGIIYKKGGVASGMKQVETNTYNIRRLLHVKGNKHVVAGEVEMSWNSFNKGDVFLLDLGSLIIQWNGPKSNRMERLRGMNLAKDIRDRERGGRAQVAVVEGDDEQSSEEAMKLMKQSLGERPKNIKEAIPDEIVDEKL-KTAIKLYHISDAQGSLVVQEVAVK-PLTQDLLKTEDCYLLDQG-GIKIFIWKGKKASKAERTESLKMAEAYVKAKGYPVSTYIETVSEGAESSVFKQLFQKWTDKGQTVG--MGTTHNPGKIAKVEQVKFDATSMHARPD--------IAAQQKMVDDGSGEAEVWRIEDNELAPVDRKWLGHFYGGDCYLILYKYEVSS-KFHYILYMWQGRHASTAELTACAYQAVILDQKYNGEPVQV---------RVPMGKEPMHLMAIFKGK-MIVYEEGSSREGSSQSRPSVRLFHVHGTNEFNTRATEVPPRSSSLNSNDVFVLSTD--KCCYLWYGKGCSGDEREMAKS-LADIISKREKQVIAEGQEPADFWVNLGGKSQYASNKRLQDE-NISITPRLFECSNQTGRFIATEIT-NFNQDDLDEDDVMLLDIWDQVYLWIGKGANDTEKREAVVTAQEYLKSHPAGRDLDTP-VLVVKQGFEPPTFTGWFHAWDPQKWSEGKSYDQLKAELGDATDVIKITVDLTQPSSN------------------QTNSSNSTQGGSMPR------PVTQTFPAEKLVNVQTEDLPEGVDPTRKEDYLSDDDFALAMGISRMNFYAMPSWKQLNLKKEKGLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9WU06-1", "uniprot_id": "AVIL_RAT", "id": "Q9WU06-1", "name": "Advillin", "aln": "--------------------------------------------------------MSLSSAFRTVTND-----------------------------PGIITWRIEKMELVLVPLSAHGNFYEGDCYIILSTR--RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKRGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNQGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMTVLQNTLGRR-SIIKPAVPDEVTDQQQ-KSTIMLYHVSDTTGQLSVTEVATR-PLVQELLNHDDCYILDQS-GTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTG--LGKTFSIGKIAKIFQDKFDVTLLHTKPE--------VAAQERMVDDGNGKVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNG-KPCYILYIWQGRHASQDELAASAYQAVEVDQQFGGAPVQV---------RVSMGKEPRHFMAIFKGK-LVIYEGGTSRKGNVEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLWTQ--AEHYLWYGKGSSGDERAMAKE-LAELLCDGDADTVAEGQEPPEFWDLLGGKAPYANDKRLQQE-TLDIQVRLFECSNKTGRFLVTEVT-DFTQDDLSPGDVMLLDTWDQVFLWIGAEANATEKEGALSTAQEYLVTHPSGRDPDTP-ILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITTDMKNATLS------------------LNSSESGPK----------------YYPVEVLLKSQDQELPEDVDPTKKENYLSERDFVSVFGITRGQFVSLPGWKQLQLKKEAGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88398-1", "uniprot_id": "AVIL_MOUSE", "id": "O88398-1", "name": "Advillin", "aln": "--------------------------------------------------------MSLSSAFRAVSND-----------------------------PRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTR--RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRR-SMIKPAVSDEIMDQQQ-KSSIMLYHVSDTAGQLSVTEVATR-PLVQDLLNHDDCYILDQS-GTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTG--LGKIFSTGKIAKIFQDKFDVSLLHTKPE--------VAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNG-KPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQV---------RVSMGKEPRHFMAIFKGK-LVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQ--AEHYLWYGKGSSGDERAMAKE-LVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQE-TLDVQVRLFECSNKTGRFLVTEVT-DFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTP-ILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLY------------------LNPSDGEPK----------------YYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75366-1", "uniprot_id": "AVIL_HUMAN", "id": "O75366-1", "name": "Advillin", "aln": "--------------------------------------------------------MPLTSAFRAVDND-----------------------------PGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTR--RVASLLSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAKIGVIEGDKEAASPELMKVLQDTLGRR-SIIKPTVPDEIIDQKQ-KSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQS-GTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMG--LGKTFSIGKIAKVFQDKFDVTLLHTKPE--------VAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNG-KPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQV---------RVRMGTEPRHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQ--AEHYLWYGKGSSGDERAMAKE-LASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRLQQE-ILDVQSRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTP-ILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITADMKNATLS------------------LNSNDSEPK----------------YYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P642-1", "uniprot_id": "A0A8M9P642_DANRE", "id": "A0A8M9P642-1", "name": "", "aln": "------------------------MEIYIGISAKLLCLLTLAAEKGLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVS--NNP-AQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQ-ISNVKLYQVSDASGQLLVQEVAVS-PLTQDLLCSSDCYILDQG-GTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQG--LGKTHSVGKIAKVDQVKFDVMELHAQPK--------LAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRAN-KPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQV---------RVVMGKEPRHFMAIFKGR-LIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTY--QTVFLWYGKGCSGDEREMGKA-VADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEE-VSLHEPRLFECSNQTGRFLMTEVA-DFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTP-ITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKSKLG---DVSQITVSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPN-QLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PU64-1", "uniprot_id": "E9PU64_RAT", "id": "E9PU64-1", "name": "Scinderin", "aln": "-----------------------------------------------------MAQELQHPEFARAGKQ-----------------------------AGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTK-SSRG-FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWQSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVATGIRDNERKGRSQLIVVEEGSEPPE------LMKVLGRKPELPDGDNDDDVIADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLPEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLHKMNYSANTQIQVLPEGGETPIFKQFFKDWKDKDQSDG--FGKVYITEKVAQIKQIPFDASKLHSSPQ--------MAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRG-----QIIYTWQGADATRDELTMSAFLTVQLDRSLGGQAVQV---------RVSQGKEPAHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPR-NNGFIWIGKGASQEEEKGAEY-VADVLKCKTT-RIQEGKEP-----------GMNSGT-LLE---EEETTRLHHCWKHRLKIILLGFMAALTK-------------LEDSLLKKFRESSPRMTWPKMMSCYLMRGNRSSFGLAKMP-MKLRKRNQ----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60604-1", "uniprot_id": "SCIN_MOUSE", "id": "Q60604-1", "name": "Scinderin", "aln": "-----------------------------------------------------MAQELQHPEFARAGQQ-----------------------------AGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTK-SSRG-FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVAIGIRDNERKGRSQLIVVEEGSEPSE------LMKVLGRKPELPDGDNDDDVVADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLQKMKYSTNTQIQVLPEGGETPIFKQFFKDWKDKDQSDG--FGKVYITEKVAQIKQIPFDASKLHSSPQ--------MAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRG-----QIIYTWQGANATRDELTMSAFLTVQLDRSLGGQAVQV---------RVSQGKEPAHLLSLFKDKPLIIYKNGTSKKEGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPR-NNGFIWIGKGASQEEEKGAEY-VADVLKCKAS-RIQEGKEPEEFWNSLGGRGDYQTSP-LLETRAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESVKSAKMYLETDPSGRDKRTP-IVIIKQGHEPPTFTGWFLGWDSSRW-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6U3-1", "uniprot_id": "SCIN_HUMAN", "id": "Q9Y6U3-1", "name": "Scinderin", "aln": "-----------------------------------------------------MARELYHEEFARAGKQ-----------------------------AGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAK-TSRG-FTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSE------LIKVLGEKPELPDGGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDG--FGKVYVTEKVAQIKQIPFDASKLHSSPQ--------MAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRG-----QIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQI---------RVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQ-NSGYIWVGKGASQEEEKGAEY-VASVLKCKTL-RIQEGEEPEEFWNSLGGKKDYQTSP-LLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTP-IVIIKQGHEPPTFTGWFLGWDSSKW-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FP1-1", "uniprot_id": "GELS_RAT", "id": "Q68FP1-1", "name": "Gelsolin", "aln": "----MAPYCSS-LRSALLVLALCALS-PSHAATASRGRAQERAPQSRVSETRPSTMVVEHPEFLKAGKE-----------------------------PGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQ-LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFQGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGSEPEA------MLQVLGPKPDLPQG-TEDTAKEDAANRRLAKLYKVSNSGGSMSVSLVADENPFAQSALRSEDCFILDHGRDGKIFVWKGKQANMDERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDG--PGLSYLSSHIANVERVPFDAATLHTSTA--------MAAQHGMDDDGTGQKQIWRIEGSNKVLVDPATYGQFYGGDSYIILYNYRHGG-RQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQS---------RVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTTPASTRLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTP--SAAYLWVGTGASDAEKTGALE-LLKVLRAQHV-QVEEGSEPDGFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTP-ITVVRQGFEPPSFVGWFLGWDDDYWS-VDPLDRALAELAA--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13020-1", "uniprot_id": "GELS_MOUSE", "id": "P13020-1", "name": "Gelsolin", "aln": "----MAPYRSS-LLCALLLLALCALS-PSHAATTSRGRAQERAPQSRVSEARPSTMVVEHPEFLKAGKE-----------------------------PGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQ-LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGGEPEA------MLQVLGPKPALPEG-TEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDG--PGLGYLSSHIANVERVPFDAATLHTSTA--------MAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGG-RQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQS---------RVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTAPASIRLFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTP--SAAYLWVGAGASEAEKTGAQE-LLKVLRSQHV-QVEEGSEPDAFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTP-ITVVRQGFEPPSFVGWFLGWDDNYWS-VDPLDRALAELAA--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06396-1", "uniprot_id": "GELS_HUMAN", "id": "P06396-1", "name": "Gelsolin", "aln": "----MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKE-----------------------------PGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQ-LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEA------MLQVLGPKPALPAG-TEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDG--LGLSYLSSHIANVERVPFDAATLHTSTA--------MAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGG-RQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQS---------RVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTP--SAAYLWVGTGASEAEKTGAQE-LLRVLRAQPV-QVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTP-ITVVKQGFEPPSFVGWFLGWDDDYWS-VDPLDRAMAELAA--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P366-1", "uniprot_id": "A0A8M9P366_DANRE", "id": "A0A8M9P366-1", "name": "Gelsolin", "aln": "--------------------------------------------------------MVYHPEFERAGKE-----------------------------PGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTIK-QTSGNLQYDLHFWLGDYCTQDESGSAAIFTVQMDDYLGGKPIQYREVQGHESKSFLGYFKKGLQYMQGGVASGFKHVVTNEVVMQRVLQVKGRRVVRATEVPVSWDSFNQGDCFILDLGNEIYQWCGSKSNRFEKLKATQLAKGIRDNERSGRARVYVCDEGVEREK------MLEVLGEKPDLPEG-ASDDVKADASNRKMAKLYKVSDASGDMAIALVAAENPFTQSALESSDCFILDHGSDGKIFVWKGKDANMEERKAAMKAADEFIKKMGYPKHTQVQILPEMGETPLFKQFFKNWRDVDQTEG--MGVAYVSNSIAKIEKVPFDASTLHDSPA--------MAAQHGMIDSGNGEKQIWRIEGSDKVPVDPSTYGQFYGGDSYIILYSYRHGG-RQGHIIYIWQGADSTQDEIGASAILGAQLDDELGGGPVQMAGAPLTTQVRVVQGKEPAHLMSLFGGQPMVVHKGGTSREGGQTAPAETRLFQVRSNSAGCTRAVEIDAVSSNLNSNDAFVLVTP--AASFIWVGQGASDIEKRGAQQ-LCGILGVSPS-ELSEGGEDGGFWDALGGKAAYRTSSRLKDK-MNAHPPRLFACSNKTGRFIIEEVPGEMTQEDLATDDVMILDTWDQVFVWIGNEAHDEEKMEAMTSAAQYIQTDPANRDPRTA-IVKIKQGFEPPTFTGWFLGWDHDYWS-TDPLERAMAELEI--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07171-1", "uniprot_id": "GELS_DROME", "id": "Q07171-1", "name": "Gelsolin", "aln": "MDASGAATMAVLSSLLVFLALSSSLCSAGTLNARPAFPVQSGEIQPSGQNSKQAARRVMHPSFANAGRT-----------------------------PGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDASGKLKVDIIGQK-PLTQAMLDTRECFILDTG--SGIFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEANNGDTGSLTYVWHGVKAS--AAARKRAFEEGLVGSKDGLLVQT-----------NQGHEPRHFYKIFKGKLLTSFT---------ALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRSLGDDGA--PLLESRLFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQLVIDANNEV---------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * :: :: . * .* *: **.:::* :*:*:* : ** .*** ..*:*: : * .:* ** * ** * .*** *: ***.:*:.:* .* *:::*** : : :* :* .*:* ** *::* * * : *. .. *:*:. : ** .:: **: : : : : . : ** :*: * : : :. *: * :*::** . * :* ** *. *: :: * :: *. * : : .*:. *:* *. * . : . : :* : . : : . : : : * .*:: *.* : * *:* .:: : . .. .* * ** *: :* .: : . :**::: . .: *: : * :.*.*:* ::* * *.* *. . . : ** * **. * :: : :: . : . : :. ", "identical_positions": 111, "similar_positions": 155, "identity": "11.43%" }, { "cls_id": "homologset.agr.FB:FBgn0010226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35543-1", "uniprot_id": "HPGDS_RAT", "id": "O35543-1", "name": "Hematopoietic prostaglandin D synthase", "aln": "----------------------------------------------MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWA--EENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGN-YVTWADFYWD-ICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHF7-1", "uniprot_id": "HPGDS_MOUSE", "id": "Q9JHF7-1", "name": "Hematopoietic prostaglandin D synthase", "aln": "----------------------------------------------MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFMSLFPWA--EKDQDLKERMFNELLTHQAPRLLKDLDTYLGDKEWFIGN-YVTWADFYWD-ICSTTLLVLKPGLLDIYPKLVSLRNKVQAIPAISAWILKRPQTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60760-1", "uniprot_id": "HPGDS_HUMAN", "id": "O60760-1", "name": "Hematopoietic prostaglandin D synthase", "aln": "----------------------------------------------MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWA--EKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGN-SVTWADFYWE-ICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41043-1", "uniprot_id": "GSTS1_DROME", "id": "P41043-1", "name": "Glutathione S-transferase S1", "aln": "MADEAQAPPAEGAPPAEGEAPPPAEGAEGAVEGGEAAPPAEPAEPIKHSYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWPALKPTMPMGQMPVLEVDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDEIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAGITDYMNYMVKRDLLEPYPALRGVVDAVNALEPIKAWIEKRPVTEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.* ***::. ** :**:*** : :*** *: : :** :*.*:*:*::*:***:* :***:::**:*:*...*.* * *: : * :***::** :. . * .:::**: : * : * ::.*: : ..: :. :****.*: * . :.* .** :* * : . *:*: .: ** :** *::", "identical_positions": 68, "similar_positions": 72, "identity": "27.31%" }, { "cls_id": "homologset.agr.FB:FBgn0010228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11633-1", "uniprot_id": "NHP6B_YEAST", "id": "P11633-1", "name": "Non-histone chromosomal protein 6B", "aln": "----------------MAATKEAKQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA--------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P11632-1", "uniprot_id": "NHP6A_YEAST", "id": "P11632-1", "name": "Non-histone chromosomal protein 6A", "aln": "----------------MVT------PREPKKRTTRKKKDPNAPKRALSAYMFFANENRDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELYNATLA--------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06943-1", "uniprot_id": "HMGZ_DROME", "id": "Q06943-1", "name": "High mobility group protein Z", "aln": "-------------------------------------MSGDRPKRPLSAYMLWLNETREQIKKDNPGSKVTDIAKRGGELWRGLK--DKTEWEQKAIKMKEEYNKAVKEYEANGGTDSGA-------PKKRKKAAAKPAKKAKKKESSEEEEEDESE--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02486-1", "uniprot_id": "ABF2_YEAST", "id": "Q02486-1", "name": "ARS-binding factor 2, mitochondrial", "aln": "MNSYSLLTRSFHESSKPLFNLASTLLKASKRTQLRNELIKQGPKRPTSAYFLYLQDHRSQFVKENPTLRPAEISKIAGEKWQNLEADIKEKYISERKKLYSEYQKAKKEFDEKLPPKKPAGPFIKYANEVRSQVFAQHPDKSQLDLMKIIGDKWQSLDQSIKDKYIQEYKKAIQEYNARYPLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** ***::: :: *. . .:** ::.: ** *: * * : : ..*:. : :: . ", "identical_positions": 15, "similar_positions": 25, "identity": "8.2%" }, { "cls_id": "homologset.agr.FB:FBgn0010235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P37285-1", "uniprot_id": "KLC1_RAT", "id": "P37285-1", "name": "Kinesin light chain 1", "aln": "MHDNMSTMVYMKEEK-----LEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESN-LVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSSKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPD-DPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE-CKG---KQKDGSSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAALRSRKQGLDNVHKQRVAEVLNDPENVEKRR-------------SRESLNVDVVKYESGPDGGEEVSMSVEWNGMRKMKLGLVK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88447-1", "uniprot_id": "KLC1_MOUSE", "id": "O88447-1", "name": "Kinesin light chain 1", "aln": "MYDNMSTMVYIKEEK-----LENVTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESN-LVEEKSSMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQNVRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDSDSSKEPLDDLFPNDEDEPGQGIQHSDSSAAAARQ--GYEIPARLRTLHNLVIQYASQGRYEVAVPSCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDRTPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEAEFGSVDDENKPIWMHAEEREE-CKG---KQKDGSAFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPESMEKRR-------------SRESLNMDVVKYESGPDGGEEA----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07866-1", "uniprot_id": "KLC1_HUMAN", "id": "Q07866-1", "name": "Kinesin light chain 1", "aln": "MYDNMSTMVYIKEDK-----LEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESN-LVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPD-DPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE-CKG---KQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRR-------------SRESLNVDVVKYESGPDGGEEVSMSVEWNGGVSGRASFCGKRQQQQWPGRRHR---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2P5-1", "uniprot_id": "A0A8M2B2P5_DANRE", "id": "A0A8M2B2P5-1", "name": "Kinesin light chain", "aln": "MREDMSSVLCVKETEGQGDLGEKLSQDELLCRTREVMQGLEALRAEHQAILEGLMGTLRCLKQSQEGR-AVEEKTAMIQRSMEMLELGLSEAQVMMALSGHLSAVEAEKQKLRAQVRRLCQENQWLRDELAGTQQRLQKSEQSVAQLEEEKKHLEFMNQLKKYDQDLSPSDDKDSDSSRETLDDLFPDEQDEPGPGIQPPHSSAVAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPD-DPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREEQSKI---KQKDGTPFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAALRSRKQGLDTAHKQRVAEVLGDPEVREKQR-------------SRESLTSDTVKYESGPDGGEEVSMSVEWNGV-------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46824-1", "uniprot_id": "KLC_DROME", "id": "P46824-1", "name": "Kinesin light chain", "aln": "--------------------MTQMSQDEIITNTKTVLQGLEALRVEHVSIMNGIAEVQ----KDNE-------KSDMLRKNIENIELGLSEAQVMMALTSHLQNIEAEKHKLKTQVRRLHQENAWLRDELANTQQKFQASEQLVAQLEEEKKHLEFMASVKKYDENQE-QDDACDKSRTDPVVELFPDEENEDRHNMSP-TPPSQFANQTSGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAANLLNDALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYDEVEKYYQRALDIYESKLGPD-DPNVAKTKNNLAGCYLKQGRYTEAEILYKQVLTRAHEREFGAIDSKNKPIWQVAEEREE-HKF---DNRENTPYGEYGGWHKAAKVDSPTVTTTLKNLGALYRRQGMFEAAETLEDCAMRSKKEAYDLAKQTKLSQLLTSNEKRRSKA-------------IKEDLDFSEEKNAKP-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F7ET11-1", "uniprot_id": "F7ET11_RAT", "id": "F7ET11-1", "name": "Kinesin light chain", "aln": "----MATMVLPREEK--------LSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGS-----QERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDSLDDLFPNEDE---QSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPD-DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKVSSTDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRSRKQGLDPASQTKVVELLKDGSGGRGDRRGSRDVAGGAGPRSESDLEESGPAAEWSGDGSGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEPPNSRMKRASSLNFLNKSVEEPVQPGGTGLSDSRTLSSSSMDLSRRSSLVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88448-1", "uniprot_id": "KLC2_MOUSE", "id": "O88448-1", "name": "Kinesin light chain 2", "aln": "----MATMVLPREEK--------LSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGS-----QERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEML-PQEEK-GDVPKDSLDDLFPNEDE---QSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPD-DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESK----DKRRDRRPM-EYGSWYKACKVDSPTVNTTLRTLGALYRPEGKLEAAHTLEDCASRSRKQGLDPASQTKVVELLKDGSG-RGHRRGSRDVAG---PQSESDLEESGPAAEWSGDGSGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEP-NSRMKRASSLNFLNKSVEEPVQPGG------RVFLTAAL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0B6-1", "uniprot_id": "KLC2_HUMAN", "id": "Q9H0B6-1", "name": "Kinesin light chain 2", "aln": "----MAMMVFPREEK--------LSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGS-----QERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDE---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPD-DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESK----DKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PQM2-1", "uniprot_id": "KLC4_RAT", "id": "Q5PQM2-1", "name": "Kinesin light chain 4", "aln": "----MSGLVLGQRDE---PAGHRLSQEEILGSTRLVSQGLESLHSEHQAVLQSLSHTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLRQLRQYDEDGHSMEEKEGDASKDSLDDLFPNEEEED-SSNDLSRGQGAAAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYERQLGPD-NPNVARTKNNLASCYLKQGKYSEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSRS--RSRESGTPYAEYGGWYKACRVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRSRKQGTDPISQTKVAELLGEGDGRKTMQEGPGD------SVKFEGGEDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQG-TEPRPSSSNMKRAASLNYLNQPNAAPLQTSRGLSASTVDLSSSS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBS5-1", "uniprot_id": "KLC4_MOUSE", "id": "Q9DBS5-1", "name": "Kinesin light chain 4", "aln": "----MSGLVLGQRDE---PAGHRLSQEEILGSTKVVSQGLEALHSEHQAVLQSLSHTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLRQLRQYDEDGHGMEEKEGEATKDSLDDLFPNEEEED-SGNDLSRGQGAAAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYESQLGPD-NPNVARTKNNLASCYLKQGKYSEAEALYKEILTCAHVQEFGSVDDDHKPIWMHAEEREEMSRS--RPRDSSAPYAEYGGWYKACRVSSPTVNTTLKNLGALYRRQGKLEAAETLEECALRSRKQGTDPISQTKVAELLGEGDGRKAIQEGPGD------SVKFEGGEDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQG-TEPRPSSSSMKRAASLNYLNQPNAAPLQVSRGLSASTVDLSSSS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSK0-1", "uniprot_id": "KLC4_HUMAN", "id": "Q9NSK0-1", "name": "Kinesin light chain 4", "aln": "----MSGLVLGQRDE---PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEED-PSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPD-NPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEEREEMSKS--RHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGD------SVKFEGGEDASVAVEWSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQG-TEPRPSSSNMKRAASLNYLNQPSAAPLQVSRGLSASTMDLSSSS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68G30-1", "uniprot_id": "KLC3_RAT", "id": "Q68G30-1", "name": "Kinesin light chain 3", "aln": "----MSVQVAAPGSTG--LGPERLNPEELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAG-VELLEEKQQVVNHSLEAIELGLGEAQVLLALSAHVGVLEAEKQRLRAQARRLAQENTWLREELEETQRRLRASEEAVAQLEEEKSHLQFLGQLRQYDPPEESQRPD-SPPRRDSLASLFPSEEEEK----KGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFQDVERHYARALSIYEALGGPQ-DPNVAKTKNNLASAYLKQNKYQQAEELYKEILS--QEALPAPLGAPQGGTAGEAQQQVLRRSS------------SFSKLRESIRRGSEKLVSRLR--GESMAGAAGMKRAMSLNMLNVDGPRAAR---MQLSTQHLNEASRTLSAST---------------QDLSPR------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W40-1", "uniprot_id": "KLC3_MOUSE", "id": "Q91W40-1", "name": "Kinesin light chain 3", "aln": "----MSVQVAAPGSTG--LGPERLNPEELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAG-VELLEEKQQVVNHSLEAIELGLGEAQVLLALSAHVSVLEAEKQRLRAQARRLAQENTWLREELEETQRRLRASEEAVAQLEEEKSHLQFLGQLRQYDPPEESQRPE-SPPRRDSLASLFPSEEEEK----KGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFQDVERHYARALSIYEALGGPQ-DPNVAKTKNNLASAYLKQNKYQQAEELYKEILS--QEALPAPLGAPQGGTAGDTQQQVLRRSS------------SFSKLRESIRRGSEKLVSRLR--GEGMAGAAGMKRAMSLNMLNVDGPRAARTQLSQLSTRHLSEAPRTLSIST---------------QDLSPR------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P597-1", "uniprot_id": "KLC3_HUMAN", "id": "Q6P597-1", "name": "Kinesin light chain 3", "aln": "----MSVQVAAPGSAG--LGPERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAG-LEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEESVAQLEEEKRHLEFLGQLRQYDPPAESQQSE-SPPRRDSLASLFPSEEEER----KGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPH-DPNVAKTKNNLASAYLKQNKYQQAEELYKEILH--KEDLPAPLGAPNTGTAGDAEQ-ALRRSS------------SLSKIRESIRRGSEKLVSRLR--GEAAAGAAGMKRAMSLNTLNVDAPRAPG---TQFPSWHLDKAPRTLSAST---------------QDLSPH------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :*:: *: * ****:*: ** .: : : : :.:* :****.****::**: *: :*:**:.:::*.*** *** ***:** **:::: **: ******** ** *: .::: * :.: .***.::: . : * *******************.********* *:*******::**: **********************:*:.**:*** ** .*** :*******************:*::*****:*********** ********.*********** : ** :* *** ** **. ****:******..****.:: :** ***::* : ..:. : ::: . . :: : .* .: : *: * . :: * :*: : : .: .. ", "identical_positions": 218, "similar_positions": 109, "identity": "33.64%" }, { "cls_id": "homologset.agr.FB:FBgn0010238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0J8-1", "uniprot_id": "NEGR1_RAT", "id": "Q9Z0J8-1", "name": "Neuronal growth regulator 1", "aln": "--MVLLAQGACCSNQWLAAVLLSLC----SCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSS----IIFAGGDKWSVDPRVSIST-LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRT-MQVHLTVQVPPKIYDISNDMTIN-EGTNVTLTCLATGKPEPAISWRHISPSAKPFENGQYLD----IYGITRDQAGEYECSAENDVSFPDVKKVRVVVNFAPTIQEIKSGTVTPGRSGL-IRCEGAGVPPPAFEWYKGEKRLFNGQQG----IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASL-------PLNPPSTAQYGITGSACDLFSCWSLALTLSSVISIFYLKNAILQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Z24-1", "uniprot_id": "NEGR1_MOUSE", "id": "Q80Z24-1", "name": "Neuronal growth regulator 1", "aln": "--MVLLAQGACCSNQWLAAVLLSLC----SCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSS----IIFAGGDKWSVDPRVSIST-LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRT-MQVHLTVQVPPKIYDISNDMTIN-EGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQYLD----IYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGL-IRCEGAGVPPPAFEWYKGEKRLFNGQQG----IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASL-------PLNPPSTAQYGITGSACDLFSCWSLALTLSSVISIFYLKNAILQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3B1-1", "uniprot_id": "NEGR1_HUMAN", "id": "Q7Z3B1-1", "name": "Neuronal growth regulator 1", "aln": "MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSS----IIFAGGDKWSVDPRVSIST-LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRT-MQVHLTVQVPPKIYDISNDMTVN-EGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLD----IYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGL-IRCEGAGVPPPAFEWYKGEKKLFNGQQG----IIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASL-------PLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24372-1", "uniprot_id": "LACH_DROME", "id": "Q24372-1", "name": "Lachesin", "aln": "--MWRPSISNCVWSTLLLAIFVQQT-------LAQRTPTISYITQEQIKDIGG-TVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGILAALLFAR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . * *:::. * :: :.: : ::: * *. : * :: . . .. : ::. :: :*. *.*.*: *. *.***:::: ** *.***.* . . :. :*:*:*: ** * * *.: .: **::* : * *:* * * *:**: . : * :.. *:. * .:.::: * * * *:*.** * :::.* *:***.* :. . : .: :.*. . ****: * *.: :* *.*: : : * * * * .* :.::*:*.* *:*::* ::* : *: **: .* *:*: :.: *. *::. ", "identical_positions": 90, "similar_positions": 124, "identity": "23.87%" }, { "cls_id": "homologset.agr.FB:FBgn0010240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63079-1", "uniprot_id": "GBRB3_RAT", "id": "P63079-1", "name": "Gamma-aminobutyric acid receptor subunit beta-3", "aln": "-----------------------MWGFAGGR-LFGIFSAPVLV----------AVVCCAQSVNDPGN------------MSFVKETVDKLLKG--------------------YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA-TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSEINR--------------------------------------VDAHGNILLAPMDVHNEMN--EVAGSVGDTRNS-AISFDNSGIQYRKQSMPKEGHGRYMGDRSIPHKK---THLRRRSSQLKIKIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIVFPFTFSLFNLVYWLYYVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63080-1", "uniprot_id": "GBRB3_MOUSE", "id": "P63080-1", "name": "Gamma-aminobutyric acid receptor subunit beta-3", "aln": "-----------------------MWGFAGGR-LFGIFSAPVLV----------AVVCCAQSVNDPGN------------MSFVKETVDKLLKG--------------------YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA-TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSEINR--------------------------------------VDAHGNILLAPMDVHNEMN--EVAGSVGDTRNS-AISFDNSGIQYRKQSMPKEGHGRYMGDRSIPHKK---THLRRRSSQLKIKIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIVFPFTFSLFNLVYWLYYVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28472-1", "uniprot_id": "GBRB3_HUMAN", "id": "P28472-1", "name": "Gamma-aminobutyric acid receptor subunit beta-3", "aln": "-----------------------MWGLAGGR-LFGIFSAPVLV----------AVVCCAQSVNDPGN------------MSFVKETVDKLLKG--------------------YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA-TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR--------------------------------------VDAHGNILLTSLEVHNEMN--EVSGGIGDTRNS-AISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKK---THLRRRSSQLKIKIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIVFPFTFSLFNLVYWLYYVN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDH7-1", "uniprot_id": "A0A8M2BDH7_DANRE", "id": "A0A8M2BDH7-1", "name": "", "aln": "MRLAGWDSLRAENMRLWWILLLSFWSVYGELPFIAENNAAMLVNWNAVDGNKKLFAIYDTSANEPGN------------MSFVKETVDKLLKG--------------------YDIRLRPDFGGAPVAVGMSIDVASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------TGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWKGGETAVTGVSRIELPQFSIVDYKLVSRNVVFS-TGAYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQMQKKLAEKAEKANNDRNKYDGNKSVQEGGNCKPSSVKQSNQVQGHRHSR-----------GVDSQGNILLTTLEIHNEVAGNEITTSVSEARNSTSMVFDNSGIQYRKQST-----ARHSMDRNAQSKK---PRLRRRSSQLKIKIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIIFPAVFSLFNLIYWLYYVN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47870-2", "uniprot_id": "GBRB2_HUMAN", "id": "P47870-2", "name": "Gamma-aminobutyric acid receptor subunit beta-2", "aln": "------------------------MWRVRKRGYFGIWSFPLII-----------AAVCAQSVNDPSN------------MSLVKETVDRLLKG--------------------YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY------------NVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFS-TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKIFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRST-MLAYDASSIQYRKAGLPRHSFGRNALERHVAQKK---SRLRRRASQLKITIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIFFPVVFSFFNIVYWLYYVN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63137-1", "uniprot_id": "GBRB2_MOUSE", "id": "P63137-1", "name": "Gamma-aminobutyric acid receptor subunit beta-2", "aln": "------------------------MWRVRKRGYFGIWSFPLII-----------AAVCAQSVNDPSN------------MSLVKETVDRLLKG--------------------YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY------------NVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFS-TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAANANNEKMRLDVNKMFYKDIKQNGTQYRSLWDPTGDLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRST-MLAYDASSIQYRKAGLPRHSFGRNALERHVAQKK---SRLRRRASQLKITIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIFFPVVFSFFNIVYWLYYVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63138-1", "uniprot_id": "GBRB2_RAT", "id": "P63138-1", "name": "Gamma-aminobutyric acid receptor subunit beta-2", "aln": "------------------------MWRVRKRGYFGIWSFPLII-----------AAVCAQSVNDPSN------------MSLVKETVDRLLKG--------------------YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY------------NVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFS-TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAANANNEKMRLDVN--------------------------------------KMDPHENILLSTLEIKNEMATSEAVMGLGDPRST-MLAYDASSIQYRKAGLPRHSFGRNALERHVAQKK---SRLRRRASQLKITIPDLTDVNAI-----------------------------------------------------------------------------------------------------------------------------DRWSRIFFPVVFSFFNIVYWLYYVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BKD0-1", "uniprot_id": "A0A8M2BKD0_DANRE", "id": "A0A8M2BKD0-1", "name": "", "aln": "------------------------MESIGKTPHI-FLLCPLIV-----------AVACAQSIRDPSN------------MPVVKDTVDRLMKG--------------------YDIRLRPDFGGAPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY------------SEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDGAVSGVERIELPQFSIVDYKLISKNVVFS-TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKAAEKAATANNEKLRPDPN--------------------------------------KMTP-DDIRLTTVEMKNEMGPSDLSRGLGDPRST-MLAYDSSTLQYRRAAMARQNYGHSALERHATQKK---SRLRRRASQLKVNIPDLSDVNSI-----------------------------------------------------------------------------------------------------------------------------DKWSRMIFPTLFSFFNIVYWLYYVH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15431-1", "uniprot_id": "GBRB1_RAT", "id": "P15431-1", "name": "Gamma-aminobutyric acid receptor subunit beta-1", "aln": "------------------------MWTVQNRESLGLLSFPVMVA----------MVCCAHSSNEPSN------------MSYVKETVDRLLKG--------------------YDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFT-TGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNKLEMNK------------------------------------VQVDAHGNILLSTLEIRNETSGSEVLTGVSDPKAT-MYSYDSASIQYRKPLSSREGFGRGL-DRHGVPGK---GRIRRRASQLKVKIPDLTDVNSI-----------------------------------------------------------------------------------------------------------------------------DKWSRMFFPITFSLFNVVYWLYYVH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50571-1", "uniprot_id": "GBRB1_MOUSE", "id": "P50571-1", "name": "Gamma-aminobutyric acid receptor subunit beta-1", "aln": "------------------------MWTVQNRESLGLLSFPVMVA----------MVCCAHSSNEPSN------------MSYVKETVDRLLKG--------------------YDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFT-TGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNRLEMNK------------------------------------VQVDAHGNILLSTLEIRNETSGSEVLTGVSDPKAT-MYSYDSASIQYRKPLSSREGFGRGL-DRHGVPGK---GRIRRRASQLKVKIPDLTDVNSI-----------------------------------------------------------------------------------------------------------------------------DKWSRMFFPITFSLFNVVYWLYYVH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18505-1", "uniprot_id": "GBRB1_HUMAN", "id": "P18505-1", "name": "Gamma-aminobutyric acid receptor subunit beta-1", "aln": "------------------------MWTVQNRESLGLLSFPVMIT----------MVCCAHSTNEPSN------------MSYVKETVDRLLKG--------------------YDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFT-TGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNKLEMNK------------------------------------VQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKAT-MYSYDSASIQYRKPLSSREAYGRAL-DRHGVPSK---GRIRRRASQLKVKIPDLTDVNSI-----------------------------------------------------------------------------------------------------------------------------DKWSRMFFPITFSLFNVVYWLYYVH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08832-1", "uniprot_id": "GBRB3_DROME", "id": "Q08832-1", "name": "Gamma-aminobutyric acid receptor subunit beta-like", "aln": "---------------------MTCFTRVGVSCGLFFFLLGAQLQ----------LIRCIRKDVLAGR------------LENVTQTISNILQG--------------------YDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKP--TPVRGVEDAELPQFTIIGYETNDRKERLA-TGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCS---------------------------------TTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMN--LGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNII-----------------------------------------------------------------------------------------------------------------------------DKYSRMIFPISFLAFNLGYWLFYILE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24046-1", "uniprot_id": "GBRR1_HUMAN", "id": "P24046-1", "name": "Gamma-aminobutyric acid receptor subunit rho-1", "aln": "-----------------------MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREV-------HEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFP-----------STNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSG------------------------------------------------LPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD------RMMVQLT-----------LASERSSPQRK------SQRSSYVSMRI----DTHAI-----------------------------------------------------------------------------------------------------------------------------DKYSRIIFPAAYILFNLIYWSIFS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GHR1-1", "uniprot_id": "A0A8I6GHR1_RAT", "id": "A0A8I6GHR1-1", "name": "Gamma-aminobutyric acid receptor subunit theta", "aln": "------------------------MGIRGMLRAAALLLLIRTWLAESNDPSPTPKFHFELSSSMPEVILDLFNCKNCANEAVVQKILDRVLST--------------------YDVRLRPNFGGAPVPVSISIYVSSIEQISEINMDYTITMFLHQTWKDTRLAY------------YETNLNLTLDYRMHEKLWVPDCYFVNSKDAFVHDVTAENRVFQLHPDGTVQYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDD-NAIHITDELHIPQYTYLGRTITSKEVYFY-TGSYMRLIVKFQVQREVRSYLVQVYWPTVLTTILSWISFWMNYGSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVCLFFVFLSLLEYVYINYLFFSQAPRRNHRRCRKPRRVVARYRYQEVVVANVQDG----------------LINVEDRVEDRAGPLPDSPMQAHLASQESLGSLMFTSEEAQLATSESLS---LLSSASSQVQLATGESLGDLPSTSEQTLPDYTIHFHGFLTNDSILPIKIRSHSDALGD------EDSEESLSSEESYGHGGSPTGRLKLQISQSA------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLF1-1", "uniprot_id": "GBRT_MOUSE", "id": "Q9JLF1-1", "name": "Gamma-aminobutyric acid receptor subunit theta", "aln": "------------------------MGIRGMLRAAALLLLIRTWLAESNGPSPTPKFHFELSSSTPEVILDLFNCKNCANEAVVQKILDRVLST--------------------YDVRLRPNFGGAPVPVSVSIYVSSIEQISEINMDYTITMFLHQTWKDTRLAY------------YETNLNLTLDYRMHEKLWVPDCYFVNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDD-NAIHITDGLHIPQYTYLGRTITSKEVYFY-TGSYMRLIVKFQVQREVRSYLVQVYWPTVLTTILSWISFWMNYDSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVCLFFVFLSLLEYVYINYLFFSQVPRRNHRRCRKPRRVVARYRYQEVVVANVQDG----------------LINVEDRVEDRAGPLPDSPMQAHLASQESLGSLVFTSEQAQLATSESLS---LLSSASSQTQLATGESLSDLPSTSEQTVPECTIHFHGFLTNDSIIPIKIHSRSDACDD------EDSEESLSSEESHGHGSSHTGRLKLQISQRCVQEASWDLDKIEILQDDISITSSWLGLDEQCKGDADSIWSLTDEELMACDQEKDSSSESEENCSPSPGCSFNEGFSFQLFKPNRVPKVDRWSRFLFPLSFGLFNVVYWLYHVY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN88-1", "uniprot_id": "GBRT_HUMAN", "id": "Q9UN88-1", "name": "Gamma-aminobutyric acid receptor subunit theta", "aln": "------------------------MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQKILDRVLSR--------------------YDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAY------------YETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFY-TGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRRVIARYRYQQVVVGNVQDG----------------LINVEDGVSS----LPITPAQAPLASPESLGSLTSTSEQAQLATSESLS---PLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPTEIRNRVEAHGHGVTHDHEDSNESLSSDERHGHG--PSGKPMLHHGEKGVQEAGWDLD-------DNNDKSDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFNPDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :. :: :*. :**.*** .: * : : : *:: :**::**:*:*:::.: *:* **:: :*:. . .::**** :* :.* :*:*..* * :.:: ** * *.:*.*.* * :*: :*:* * *.: :***.** .*: : * .: :.*: : ** * ** :.* ::*.: ::.*.* *: * .: **:***:: : .***.:*:*::* ::** : :. .:*.:. :**:*:*: .:.*** ::***. :** : : : :: * : * :. ", "identical_positions": 89, "similar_positions": 123, "identity": "12.33%" }, { "cls_id": "homologset.agr.FB:FBgn0010246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R829-1", "uniprot_id": "M0R829_RAT", "id": "M0R829-1", "name": "", "aln": "--------------------------------------------------MGSKKEEVRRKHIRLHMEGALTARDKVGVQDFVLLDAYTSESAFLENLRKRFRENLIYTYIGTLLVSVNPYQELGIYTSSQMELYQGVNFFELPPHVYAIADNAYRMMCSELNNHFILISGESGAGKTEASKKILQYLAVTC-PMTESLQIARDRLLLSIPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFQGVPVGGHIISYLIEKSRVVYQNHGERNFHIFYQLLAGGKSERLASLGLER-DPQLYKFLSQGHCARESPSNDRSDWETVYSAFSVIGFTEADLENLFGIIASVLHLGNICFKGDKQGCASIPDTHEIKWIAKLLGVCPAVLLEALTHRKIEAKT-----EEVICPLTVELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKD----------FTQKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYESEGIEWEPVQYFNNKIICDLVEERHRGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFQTRKLAGPKGRKRIGWLEFCLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCSSKNSILRECFLVAE-LENRKRPPTVGTQFKNSLSSLLEILISKEPSYIRCIKPNERKEPSKFDDFLISHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGP----PGEGVERLIKYIGYQPQDYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVSRIQATYKGCLGRREYVRKRQAATKLEAHWRGVLARK----------EIKRRKWAVQIIRRFIKGFINRDKPL-------------------------------------------------------------CPDNEEFLLLVRKNYILNLRYHVPKNVLDKS-WLRPPGILENASNLLRRMCTRNLVRKYCRGISAERKAMMQQKAVTSGLFRGKKEGYAESLSQPFASSRLDEGKINPK-----------VLQLLGSE-KIQYGVPVIKYDRKGFKARQRQLLLTLRSAYLVEFSKIKQKMEY-SALRGVSTSSLRDGILVIHVSPADKQQKGDTILQCEHIFEVATKLAMLIKREHVVRVV--------------------------QGSLQFCVSPGREGTIVFETGEEDQVYKDKNGQLRVVSAGKKT--------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6A1-1", "uniprot_id": "MYO1H_MOUSE", "id": "Q9D6A1-1", "name": "Unconventional myosin-Ih", "aln": "------------------------------------------------------------------MEGALTARDKVGVQDFVLLDAYTSESAFLENLRKRFRENLIYTYIGTLLVSVNPYQELGIYTASQMELYQGVNFFELPPHVYAIADNAYRMMCSELNNHFILISGESGAGKTEASKKILQYFAVTC-PMTESLQIARDRLLLSIPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFQGVPVGGHIISYLIEKSRVVYQNHGERNFHIFYQLLAGGGSERLASLGLER-DPQLYKYLSQGHCARESPISDKNDWETVCGAFSVIGFTEADLENLFGIIASVLHLGNVCFKGDKQGCASVPDTHEIKWIAKLLGVCPAVLLEALTHRKIEAKT-----EEVICPLTVELSVYARDAMAKAVYGRTFTWLVNRINSSLVNKD----------FTQKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYESEGIEWETVQYFNNKIICDLVEERHRGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFQTRKLAGPKGRKRIGWLEFCLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCSSKNSILRECFLVAE-LENRRRPPTVGTQFKNSLSSLLEILISKEPSYIRCIKPNERKEPSKFDDFLISHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGP----PGEGVERLIKYIGYQPQDYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVSRIQATYKGCLGRREYMKKRQAATKLEAHWRGVLARK----------EIKRRRWAVQIIRRFVKGFINRDKPL-------------------------------------------------------------CPDNEEFVVLVRKNYILNLRYHVPKNVLDKS-WLRPPGILENASNLLRRMCTRNLVRKYCRGISAERKAMMQQKVVTSEIFRGKKEGYAESLNQLFAGSRL-----------------------------------------------------------------------------GVSTSSLSDGILVIHISPADKQQKGDVILQCEHIFEVATKLAMLIRKEHTVRVV--------------------------QGSLQFYVSPGREGTIVFETGEEDQVYKDKNGQLRVVSAGKKT--------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1T3-1", "uniprot_id": "MYO1H_HUMAN", "id": "Q8N1T3-1", "name": "Unconventional myosin-Ih", "aln": "------------------------------------------------------------------MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTC-PMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLER-DPQLYKYLSQGHCAKESSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHPSVLLEALTHRKIEAKT-----EEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKVGQRILDPLLLLTWKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFLLAE-LENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGP----PAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARK----------AIQRRKWAVRIIRKFIKGFISRNKPL-------------------------------------------------------------CPDNEEFIVFVRKNYILNLRYHLPKTVLDKS-WLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPK-----------VLQLISHE-KIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQKIEY-SALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGHVFEAVTKLVMLVKKENIVNVV--------------------------QGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTVVSVRRKS--------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B9I7-1", "uniprot_id": "A0A8M3B9I7_DANRE", "id": "A0A8M3B9I7-1", "name": "Unconventional myosin-Ic", "aln": "-------MAQSYRLHQ----------------------CKQIVSWSVL--CLSDWQKGKVKLGQLDLEGALIARDRVGIQDFVLLDAHNSETAFLDNLKKRFTEDLIYTYIGTLLISVNPYKELDIYTKKQMDLYMGVNFFELPPHIYALADNAYHTMLSEANNHFILISGESGAGKTEASKKILQYYAVSC-PSSTLLDTVRDRMLMSNPVLEAFGNAKTMKNDNSSRFGKYMDIQFDIQGDAVGGHILSYLLEKSRVVHQNHGERNFHIFYQLVEGGEEDLLRQLGLER-DTKRYCYLVQGECSNVSSINDKNDWKTVKNALSVIDFDASDTEHLFGIISSVLHLGNVHFDRDTKGYAILNSNAALRWVSKLLGVHVQVLHGALTFRKIEAKS-----EEVLSPYTVDHAIYARDALAKAIYDRAFTWLVNRINESLENKD----------SERKTVIGLLDIYGFEVFTANSFEQFCINYCNEKLQQLFIQLTLKAEQEEYEAEGIGWEPVQFFNNKIICDLVEEKHRGIISVLDEECVRPGDATDLTFLEKLEEKMGNHPHFVTHKLADKKTRKSLERGDFRLLHYAGEVTYCVVGFIDKNNDLLYKNIKDMMRLSKNPIIQQCFPATK-AESRRRPETVATQFKNSLLRLTEILTAKEAWYVRCLKSNDNKQQGKFDEVLVRHQVKYLGLMEHLRVRRAGFAYRRKYEVFLKRYKPLCPATWPHWRGV----PSEGVEKLVQHLGYQPDEYKMGRTKIFIRYARTLFATEDAFEICKHELATKLQAKYKGYKVKGEFRKQKEAATKIETCWRGVQARK----------ERDRRAWAVKVIKKFIKGYLTRREAK-------------------------------------------------------------TTDNSEYLAFVRQSYLNRLKANLPKTVLDKTTWLTPPPVMTETSEILRKLHTRMMVRKYVRGITPQKKAQMQQKVVTSAIFKGKKDSYPSSIAVPFVDTRINEQDINMR-----------VLQTIRHE-RIKYSVPVVKYDRNGFKPRQRQLILTQAAAHLVEEAKIKQRVDY-VSLKGASVSNLGDSVMILHVAFNDPKQKGDLVLQCDHLFEALTKLAMIANKQNNITVV--------------------------QGSIKFEIQAGKQNAVDFSTGQEPMIYKGPNGHLMVVAPRIKSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JPG2-1", "uniprot_id": "A0AC58JPG2_DANRE", "id": "A0AC58JPG2-1", "name": "", "aln": "MSLISLRIACPVRLYERFVYENSRTLKKKYPILYQESAVKHVCGAAELSDCINKSLEERCQRILQEMEGSLTARDRVGIQDFVLLDAYTSETAFMDNLKKRFNENLIYTYIGTLLVSVNPYKELGIYTKKQMDIYMGVNFFELPPHIFALADNVYRTMISETSNHFILISGESGAGKTEASKKVLQFYAVSC-PSTRLLDNVRDRLLLSNPVLEAFGNAKTLKNDNSSRFGKYMDIQFDHQGAAVGGHILSYLLEKSRVVHQNHGERNFHIFYQLVEGGEDELLRWLGLER-NCQSYRYLIQGECAKVSSINDKSDWKTVQKALTIIEFSEKDIEHLFAIIASVLHLGNVHFEATFQGYARLNSSGEIHWLSKLLGIPSDMLQEGLTHRKIEAKA-----EEVLSPFTAEHAKYARDALAKAIYGRTFSWLVNKINESLANKD----------STRKTVIGLLDIYGFEVFDVNSFEQFCINFCNEKLQQLFIQLTLKSEQEEYEMEGIEWEPVPYFNNKIICDLVEEKHRGIISVLDEECLRPGEATDFTFLEKLEGKMSGHPHFVTHKLADQKTRKTLERGDFRLLHYAGEVTYSVVGFLDKNNDLLYRNIKEVMRQSKNSIIQHCFHTIE-PDGKKRPETVATQFKNSLAGLTEILMTKEPWYVRCLKPNHCKQPDRFDDVMVRHQVKYLGLMEHLRVRRAGFAYRRRYEVFLKRYKALCPDTWPHWKGT----PAEGVQRLIKHLGYKTDEYKMGRTKIFIRHPRTLFATEDAFEVCKHELATRIQAKYKGYRVKGDYLRQREAATKIETCWRGLQARR----------ERERRAWAVKVIKKFIKGFMNRNQPV-------------------------------------------------------------SMDNSEYLAFVRQSYLTRLKENLPKSVLDKTTWLTPPPIMQEASVLLRNLYTRLLVRKYVRGISAQRKMQLQTKALTSEIFRGRKESYPQSVCQPFADTRISEQDINIK-----------VLQLICPE-GIKYSVPVIKYDRNGFRPRFRQLIFTQAAAYLVEEAKIKQRVNY-SSLKGVSVSNLSDNFLILHVACEDTKQKGDLVLQCSYLFEALTKICVVTKNRSLIKVV--------------------------QESVRFDIQPGKEGFVDFKSSSESMVYRAKNGHLMVESARTKSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63355-1", "uniprot_id": "MYO1C_RAT", "id": "Q63355-1", "name": "Unconventional myosin-Ic", "aln": "--------------------------------------------------MRYRASALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYTRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETC-PAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHVFYQLLEGGEEEALRRLGLER-NPQSYLYLVKGQCAKVSSINDKSDWKVVRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKG-----EELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAES-----PSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTIKHHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSTNPIMAQCFDKSE-LSDKKRPETVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPVWTGR----PQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR----------KAAKRKWAAQTIRRLIRGFILRHAPR-------------------------------------------------------------CPENAFFLDHVRTSFLLNLRRQLPRNVLDTS-WPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPR-----------VLQALGSE-PIQYAVPVVKYDRKGYKPRSRQLLLTPSAVVIVEDAKVKQRIDY-ANLTGISVSSLSDSLFVLHVQREDSKQKGDVVLQSDHVIETLTKTALSADRVNNININ--------------------------QGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTI7-1", "uniprot_id": "MYO1C_MOUSE", "id": "Q9WTI7-1", "name": "Unconventional myosin-Ic", "aln": "-------------------------------MALQVELIPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETC-PAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHVFYQLLEGGEEETLRRLGLER-NPQSYLYLVKGQCAKVSSINDKSDWKVMRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKG-----EELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAES-----PSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKPHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSMNPIMAQCFDKSE-LSDKKRPETVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPMWAGR----PQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR----------KAAKRKWAAQTIRRLIRGFILRHSPR-------------------------------------------------------------CPENAFFLDHVRASFLLNLRRQLPRNVLDTS-WPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPR-----------VLQSLGSE-PIQYAVPVVKYDRKGYKPRPRQLLLTPSAVVIVEDAKVKQRIDY-ANLTGISVSSLSDSLFVLHVQREDNKQKGDVVLQSDHVIETLTKTALSADRVNNININ--------------------------QGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00159-1", "uniprot_id": "MYO1C_HUMAN", "id": "O00159-1", "name": "Unconventional myosin-Ic", "aln": "-------------------------------MALQVELVPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETC-PAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLER-NPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKG-----EELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVES-----PSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSE-LSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR----PQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR----------KAAKRKWAAQTIRRLIRGFVLRHAPR-------------------------------------------------------------CPENAFFLDHVRTSFLLNLRRQLPQNVLDTS-WPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPR-----------VLQALGSE-PIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRIDY-ANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQSDHVIETLTKTALSANRVNSININ--------------------------QGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAVVAPRLNSR-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF48-1", "uniprot_id": "MYO1C_DANRE", "id": "A5PF48-1", "name": "Unconventional myosin-Ic", "aln": "------------------------------------------------------------------MESALSARDRVGVQDFLLLENHNSEAAFIENLRRRYREGLIYTYIGSVLVSVNPYKELEIYSKQNMERHRGVNFYEISPHIFALADNSYRALRTERRDQCILISGESGAGKTEASKKILQYYTHIC-PTRNNTHTIRERLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDYKGAPIGGHILNYLLEKSRVAHQNHGERNFHIFYQLLEGGEDLLLKRLGLDKTNPQHYHYLIKGNCPRVSSISDKNGWKVVRNALTIIGFEDEEIQALMEIVASVLHLGNTQFGEDEEGETHITTEAQLQFLSQLLGVDGSVLKAALTHKKIVAKG-----EEMISPLSLEQALSARDSFAKAIYGRAFTWLVQKLNRSLAFKDEIY-----YSSKCSSVIGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEG--WERVEYFNNKIICDLVEEKHKGIIAILDEECLRRGDASDITFLEKLEDTLGGHAHFITHKMANGKIRKAIGREEFRLVHYAGEVNYNVNGFLDKNNDLLYRHLKEVLCQSTNHIVSQCFHADE-LMDQRRPETAATQFKLSLAKLMDILMSKEPSYVRCIKPNDGKQPGRFDEVLVRHQVKYLGLMENLRVRRAGFAYRRSYEAFLERYKSLCPDTWPNWHGN----LPEGVATLVKHLNYKPEEFKLGRSKIFIRFPRTLFITEDALEAQKQTIAVTLQKSWRGYRERANYHRIRHAVIVIQSWWRGVKGRR----------KAKHRRQAADTIRNFIKGFILRNEPR-------------------------------------------------------------CPDNEYFLDHVRFSFLMKVKRNLPKSVLDKS-WPKPPPSLTEASEHIHRICIRNLVNDYCRRIQPEWRKQLEQKVVASGIFKGQKDGYSRSVPKLFVATRLEAEEINLK-----------VLQTLGSDNKVKYGIAVTKYDRHGFRPRVRQLLLTTSSAVLVQEAKIKQRIDY-GALLGISVSSLSDGFFVLHIPTADSKQKGDLVLQCDHVIEAVTKLAIMADKIHNVNIS--------------------------QDSIRFAIARGKEGVIDFTSGSDLRVVKSKNGHLSVTTPRIS---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23979-1", "uniprot_id": "MY61F_DROME", "id": "Q23979-1", "name": "Unconventional myosin IC", "aln": "---------------------------------------------------------MASFNSQLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACS-GNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLER-ALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFT-EVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARG-----DVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETR--------ASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKE-LRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGG--PKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQ----------AAKKRREAADKIRAFIKGFITRNDAP-------------------------------------------------------------NGFNEEFIANAKRMWLLRLAKELPTKVLDKS-WPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVND--------FVASTFGSE-QLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDKIDFTLTNHNDDLMVIRIPLDLKKDKGDLILIIPRIIEFSTYIIDTVGTASIVSIVD-------------------------RNSLEHNVVKGKGGVIDIQTGAEPGVVRDK-GHLVIIGTQ-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04439-1", "uniprot_id": "MYO5_YEAST", "id": "Q04439-1", "name": "Myosin-5", "aln": "-----------------------------------------MAILKRGARKKVHQEPAKRSANIKKATFDSSKKKEVGVSDLTLLSKISDE-AINENLKKRFLNATIYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVPPHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVVSQIKNERNFHIFYQFTKGASDAYRQTFGVQK--PEQYVYTAAAGCISAETIDDLQDYQETLKAMRVIGLGQEEQDQIFRMLAAILWIGNVSFIENEEGNAQVRDTSVTDFVAYLLQIDSQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWIVSRVNKSLQAFP-----------GAEKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYEREKIQWTPIKYFDNKVVCDLIEARRPPGIFAAMNDSVATAHADSNAADQAFAQRLNLFTTNPHFDLRSNK---------FVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFPDTVDRESKRRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLHQIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYILQDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRRIDAATKIQRTIRERKEGNKYEKLRDYGTKVLGGRKERRSMSLLGYRAFMGDYLSCNESKSKGAYIKRQVSIKEKVIFSIHGEALHTKFGRSAQRLKKTFLLTPTTLYIVGQTLVQNAMTYTQDYKIDVRNIQAVSLTNLQDDWVAIKLASSGQPDPLINTYFKTELITHLKRLNDKIQIKIGSAIEYQKKPGKLHSVKCQINESAPKYGDIYKSSTISVRRGNPPNSQVHKKPRKKSSISSGYHASSSQATRRPVSIAAAQHVPTAPASRHSKKPAPPPPGMQNKAATR----------RSVPNPASTLTASQSNARPSPPTAATRATPAATPAAAAMGSGRQAN---IPPP-----------------------PPPPPPSSKPKEPMFEAAYDFPGSGSPSELPLKKGDVIYITREEPSGWSLGKLLDGSKEGWVPTAYMKPHSGN-NNIPTPPQNRDVPKPVLNSVQHDN-----------TSANVIPAAAQAS-----LGDGLANALAARANKMRLESDDEEANED-EEEDDW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36006-1", "uniprot_id": "MYO3_YEAST", "id": "P36006-1", "name": "Myosin-3", "aln": "-----------------------------------------MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDE-SINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQM--PEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFP-----------GADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANK---------FVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLS-GKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...*:.*: **. .* :: **::*: : ****** :*:****:::* **: :. : . *:.**::*:::. : : .: ::******:*****:*::::: : . :: :* : *:**:** *:* :*:****.***::::*: : . .*:* .**:**.**. * .*****:***: *. . : :: . * : . .* ..:: *: * : : :: :::::* :** * .. : : : ** : * *. : : : . * . : .**::***:*.. * *:* ::* ** . :*:*******:* *.***:***: ******::*: ***:** *. * * : :*:**::*:*:* : * ::.: . . . : : : : . . : * : ****:*.* *: :**:* * :.: : : : * :: * . :** *. :: * * : * :. *:* :*.*. : . ::: : **:***** *::*:********: :* *::*: *. .* ::: ..:::* :.:**: ..:** *. : :. :* :: : : : : :* : : :: .:: . : : : .: . * .: . : : .: : : . : * * : . . . : . : . : . . *.: ", "identical_positions": 194, "similar_positions": 262, "identity": "14.51%" }, { "cls_id": "homologset.agr.FB:FBgn0010247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27008-1", "uniprot_id": "PARP1_RAT", "id": "P27008-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MAEATE-RLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRQPDTEVDGFSELRWDDQQKVKKTAE-AGGVAG-KGQHGGGGKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQMRLSKKMLDPEK-PQLGMIDRWYHPTCFVKNRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAVKSEGKRKCDEVDGIDEVAKKKSKKGKDKESSKLEKALKAQNELVWNIKDELKKACSTNDLKELLIFNQQQVPSGESA-ILDRVADGMAFGALLPCKECSG-QLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREIS-YLKKLKIKKQDRLFPPESSAPAPPAPPVSITSAPTAVNSS------APADKPLSNMKILTLGKLSQNKDEAKAMIEKLGGKLTGSANKASLCIS-TKKEVEKMSKKMEEVKAANVRVVCEDFLQDVSASAKSLQELLSAHSLSSWGAEVKVEPGEVVVPKGKS-AAPSKKSKGAVKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLESDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLAVKPGTKSKLPKPVQELVGMIFDVESMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQAVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNTDSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTAPDPSAS-ITLDGVEVPLGTGIPSGVNDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11103-1", "uniprot_id": "PARP1_MOUSE", "id": "P11103-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MAEASE-RLYRVQYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGQSIRHPDVEVDGFSELRWDDQQKVKKTAE-AGGVAG-KGQDGSGGKAEKTLGDFAAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEK-PQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSRKETDKYS-KLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESA-ILDRVADGMAFGALLPCKECSG-QLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREIS-YLKKLKVKKQDRIFPPESSAPITVHWPLSVTSAPTAVNSS------APADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCIS-IKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQDLLSAHSLSPWGAEVKAEPGEVVAPRGKS-AAPSKKSKGCFKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRLGTVIGSNKLEQMPSKEEAVEQFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVDSMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQPVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLIMLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSAS-ITLEGVEVPLGTGIPSGVNDTALLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09874-1", "uniprot_id": "PARP1_HUMAN", "id": "P09874-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MAESSD-KLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAE-AGGVTG-KGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEK-PQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDS-KLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESA-ILDRVADGMVFGALLPCEECSG-QLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREIS-YLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSS------ASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCIS-TKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSAN-ISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHR0-1", "uniprot_id": "PARP1_DANRE", "id": "Q5RHR0-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MADSQDDKLYKAEYAKSGRASCKKCKDNIAKDSLRMAIMVQSPMFDGKVPHWHHFSCFWLR-AAVQSP-SDISGFTDLRWDDQEKVKTAIE-SGGATGGKGGQKGAAKGEKTLNDFAVEYAKSNRSTCKGCDQKIEKDQIRVSKKTVDPEK-PQLGLIDRWYHTGCFVSRREELIFKPEYSAAQLKGFAVLRDEDKEELKKRLPAVKSEGKRKADEVDGG--VSKKQKKEDE-----KLEQNLKDQSQLIWGIKDKLKKFCSINDMKELLIANSQEVPSGESN-IVDRLSDCMAFGSLKPCETCKG-QLVFKSDAYYCTGDISAWTKCVFKTQTPDRKDWVTPKEFSEIP-FLKKFKFKRQDRVFPKDAPPAAATPSSGSTTSAATSVSSASKNLTEAPADKPLTGMKLLAVGKLSKNKDDLKKFVEDLGGKITGTASKAALCIS-SKKEIEKMSKKMEEVRDAGVRVVADDFLTDIKESGKALQELISLHAISPWGAEVKVEAP-AAAAATKSTGAHSSKSTGKVKEEEGGSKSKKMKLTVKGGAAVDPDSGLENCAHVLEQNGKIYSATLGLVDIVRGTNSYYKLQLLEDDVQKRYWVFRSWGRVGTTIGGNKLDKFYDKNSAMDNFCGVYEEKTGNAWASS-NFTKYPNKFYPLEIDYGQDEEAVKKLTQSAGAKSQLEKPVQDLIRMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSLLSEVQQAVADSSSESLILDLSNRFYTLIPHDFGMKKPPLLSNVDYIQQKVQMLDNLLDIEVAYSLLRGGVENNEKDPIDINYEKLKTKIEVVDKSSHEAQLILQYVKNTHAATHNTYTLDVEEIFKIEREGEYQRYRPFKELPNRQLLWHGSRTTNYAGILSQGLRIAPPEAPVTGYMFGKGVYFADMVSKSANYCHTSQADPVGLILLGEVALGNMHELKKASHITKLPKGKHSVKGLGRSAPDPRAT-VSLNGVDIPLGKGMNTNIDDTSLLYNEYIVYDVSQVNLKYLLKIRFNYQTSLW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35875-1", "uniprot_id": "PARP1_DROME", "id": "P35875-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MDIELP---YLAEYARTGRATCKGCKSTISKDTLRIAVMVQSAFHDAKVPNWFHKTCFFKN--QRPSSVGDIQNIGNLRFADQKELTDLVENIQEVISAQLGKKRSKAFNLALKDFGIEYAKSSRSTCRGCEQKINKDLVRLRKTVYDTEVGMKYGGQPLWHHLECFAQLRSELGWF--ASGEDMPGFQSLADDDQAKVKNAIPPIKSE--ELPDTKRAKMELSDTNEEGEK-------KQRLKDQNDAYFRFRDDIKNKMKKKDIDILLKFNNQQPVTGDTEKLFDQTADLLTFGAIESCSECNSCQFIVNKSGYICNGNHSEWTKCNKLLKEPTRSACIVPKELKALYNFLNTVKEIPSTRIFNNFPPNKSTFSRSLLKTNKNNDVLVRP---TIPRISPPLYNLKFSIIGLKNQHK-ELRKRIENLGGKFEVKISENTIAIISTELEIQKKSTRMKFAEELGIHIVPIEFLDFVEADTEGAIKYINSTCICSWGTDPKSRIPKETTKSLNS-NSIYTKSMPVSR-----------TFKVKDGLAVDPDSGLEDIAHVYVDSNNKYSVVLGLTDIQRNKNSYYKVQLLKADKKEKYWIFRSWGRIGTNIGNSKLEEFDTSESAKRNFKEIYADKTGNEYEQRDNFVKRTGRMYPIEIQYDDDQKLVKHESHFF--TSKLEISVQNLIKLIFDIDSMNKTLMEFHIDMDKMPLGKLSAHQIQSAYRVVKEIYNVLECGSNTAKLIDATNRFYTLIPHNFGVQLPTLIETHQQIEDLRQMLDSLAEIEVAYSIIKSEDVSDACNPLDNHYAQIKTQLVALDKNSEEFSILSQYVKNTHASTHKSYDLKIVDVFKVSRQGEARRFKPFKKLHNRKLLWHGSRLTNFVGILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSANYCCTSQQNSTGLMLLSEVALGDMMECTSAKYINKLSNNKHSCFGRGRTMPDPTKSYIRSDGVEIPYGETITDEHLKSSLLYNEYIVYDVAQVNIQYLFRMEFKYSY---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:**::***:** *...*.**:**:*:****.:.*.***:*.* :**: . ::..: :**: **:::. * . . : . . : :* **. *****.** *:** :**:*. :*: *. *.* : * *:* **.. *.** : *. :: ** * :*: :*: :* :*.* . * . ::..:.. :: ** *.: : ::*.:*: . :*:. ** *.*: :*:: :.*: :* :.**:: .*. *.. *::.:...* *.*: : **** : * *. :.***: : :*:..* . *:* .. . . :. * . . ** .:*: :* .::* : : :*.****: . .: ::.* : *::* ..:*: .. .:::* :** :. . :. . : :..**:: * . .. :* : .** : .:.:*.* *********. *** ...: :*..***.** :..*****:***: * :.:**:******:** **..**::: .:.* :* :* :**** : . **.* . ::**:**:*.:*:: **: : .*:* .**:*: :***::**:*:::*:.**::******** :***:** ::.*: : : .*. : ::* :*********:**:: *.*:.. : :: :***.* :******:::. .. :*:* :* ::**.: .:*:.*.* .:: :*******:**::* *.: ::**:.*:** :*::**::* **:******* **:.****:********** ********:************* *** :. **::*.*****:* * . *.:*.**.:.*** * *:: *** . : :**::* * : .:.**********::***::**:::.*::. ", "identical_positions": 362, "similar_positions": 355, "identity": "35.11%" }, { "cls_id": "homologset.agr.FB:FBgn0010258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LU98-1", "uniprot_id": "A0ABK0LU98_RAT", "id": "A0ABK0LU98-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "-------------------------MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG-------------AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVPKED---------IHAGGGG--ARAARGGRGGGRGRGGGGGGGGGRDQNGLAKGGGGG----------YNSYGG-YGG-----YGAYGG-------GGGGG-SYGGSDYGNGFGGFG---SYSQHQSSYGP---------------MKSGGGGGGGGGSWGGRSNSGPYRGGYGGGGGGG--YGGGSF----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX86-1", "uniprot_id": "ROA0_MOUSE", "id": "Q9CX86-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "-------------------------MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG-------------AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVPKED---------IHAGGGG--ARAARGGRGGGRGRGGGGGGGG-RDQNGLAKGGGGGGG-------GYNSYGG-YGG-----YGAYGG-------GGGGGGSYGGSDYGNGFGGFG---SYSQHQSSYGP---------------MKSGGGGGGGG-SWGGRSNSGPYRGGYGGG------YGGGSF----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13151-1", "uniprot_id": "ROA0_HUMAN", "id": "Q13151-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "-------------------------MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPG-------------AHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKED---------IYSGGGGGGSRSSRGGRGG-RGRGGG------RDQNGLSKGGGGG----------YNSYGG-YGGGGGGGYNAYGG-------GGGGS-SYGGSDYGNGFGGFG---SYSQHQSSYGP---------------MKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGG----YGGSSF----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T746-1", "uniprot_id": "A0AB32T746_DANRE", "id": "A0AB32T746-1", "name": "", "aln": "------------------------MSEMEKLCKLFVGGLNVQTTNDGLRSYFEQFGNLTDCVVVQNDQLQRSRCFGFVTYSTSEEADAAMAARPHVVDGKNVEVKRAVAREDAGRPE-------------ALAKVKKIFVGGLKDDIEEKDLTEFFSQFGMIEKSEVITDKDTGKKRGFGFVHFEDNDSADKAVVLKFHMINGHKVEVKKALTKQE---------IQAAGGA------RGGRGRGGGRGMG------RNQNGFGGGRGGG----------YGGYGGGYGGGYGGNDGGYGGSYGSGGYGGGYGGGYGGG-YGEQMGGYGGGNGYSDFGSGYGQ---------------QSSGYGPMKGGNTYGGRS-GAPYPRGGGGGPG----YGRGGYGGY-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFT3-1", "uniprot_id": "Q9VFT3_DROME", "id": "Q9VFT3-1", "name": "", "aln": "MDAGNCASSACLGDCKGDGKTAIKEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKADRRFRFPIFSSVRAGYIPPQPATADSYNYNNPNYNPYLAQSVLPPSAFTNGWAHYVIPMAPKPTPGQNMAASLPSQQLAEHSLNGHGPDMWSSYPKTGIYSAQEWTSSKVAEWGPKAGHKHAQTSTNDRAKIDLKELQAATFNNKLDFGARGDADRMSGAGLGLGLTGGAAVGVGAIKKWPTQDYKVFKPAKSPTNGVIPKIGKEATTPPYGI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* *:*:***..**: . **..*. ** ::*.**: : ::** ****** :..: . * **.:*.: ** *:*:.*:* * . : *::*:**** * : *.***** : . ::: *:::*::*.***: * . .:*:** . : * * ****:: * : .* .. . . ..: * . . .. . . * . . .. .. :* .:.. :. . . . * .. .* . . * . * : .: ", "identical_positions": 73, "similar_positions": 98, "identity": "17.06%" }, { "cls_id": "homologset.agr.FB:FBgn0010263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CH84-1", "uniprot_id": "ELAV2_RAT", "id": "Q8CH84-1", "name": "ELAV-like protein 2", "aln": "-----------------------------------------------------------METQLSNGPTCNNTANGPTTVNNNCSSPVDSG------------NTEDSKTNLIDNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG---ISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPN-----RRYPGPLAQQAQRFRLDNLLNMAYGVK-------RFSPMTIDGMTS--LAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60899-1", "uniprot_id": "ELAV2_MOUSE", "id": "Q60899-1", "name": "ELAV-like protein 2", "aln": "-----------------------------------------------------------METQLSNGPTCNNTANGPTTVNNNCSSPVDSG------------NTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG---ISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPN-----RRYPGPLAQQAQRFRLDNLLNMAYGVKS------RFSPMTIDGMTS--LAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12926-1", "uniprot_id": "ELAV2_HUMAN", "id": "Q12926-1", "name": "ELAV-like protein 2", "aln": "-----------------------------------------------------------METQLSNGPTCNNTANGPTTINNNCSSPVDSG------------NTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG---ISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPN-----RRYPGPLAQQAQRFRLDNLLNMAYGVK-------RFSPMTIDGMTS--LAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IEW8-1", "uniprot_id": "ELAV4_DANRE", "id": "A0A0R4IEW8-1", "name": "ELAV-like protein 4", "aln": "--------MFEISRTLNAALLSNEGSTETQWRQADLPQ--LQGWAEKGLLTQPKMIISNMEPQVTNGPNS-ATANGPSSNSRSCPSPMQTGG-----------SNDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGPTGGSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAAEPITVKFANNPSQKTSQALLSQLYQSPN-----RRYPGPLHHQAQRFRLDNLLNMAYGVK-------RFSPITIDSMTS--LVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AYA7-1", "uniprot_id": "A0A8M3AYA7_DANRE", "id": "A0A8M3AYA7-1", "name": "ELAV-like protein", "aln": "----------------------------------------------------MVTIISTMETQVSNGPSGTSLPNGPVISTN--------G------------ATDDSKTNLIVNYLPQNMTQEEFKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKDMEQLFSQYGRIITSRILVDQVTAG--ISRGVGFIRFDKRNEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTQLYQTAA-----RRYTGPLHHQTQRFRLDNLLNASYGVKSSLSVLPRFSPITIDSMTS--LAGVNLTGPTGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTSKQHKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PBZ2-1", "uniprot_id": "M9PBZ2_DROME", "id": "M9PBZ2-1", "name": "", "aln": "MVEGQTAVQQQQQQPSGAGGASGVGSTTGSAGGPATANNVTNSQAQTNGGTTATTTAAAGAGSTTNAAVGQATANNAASNNNNNNNNTNNNNNNNATANNNNNNEPDPKTNLIVNYLPQTMSQDEIRSLFVSFGEVESCKLIRDKVTGQSLGYGFVNYVKQEDAEKAINALNGLRLQNKTIKVSIARPSSESIKGANLYVSGLPKNMTQSDLESLFSPYGKIITSRILCDNITG---LSKGVGFIRFDQRFEADRAIKELNGTTPKNSTEPITVKFANNPSSNKNSMQPLAAYIAPQNTRGGRAFPANAAAGAAAAAAAAAIHPNAGRYSS--VISRYSPLTSDLITNGMIQGNTIAS---SGWCIFVYNLAPDTEENVLWQLFGPFGAVQSVKVIRDLQSNKCKGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVSFKTNKNKQTXLLTKLAAVVNANAAAAALAANGLVLHNHHHHSNIGSINNNSNNSNGCSAAAFPLGKYVNHSSNNRQHNINNSTSNTSKQKPASTSNKQQSMAPPKRLASSTAATTGDLAATAATNSSSSSHSASSGDAGATGTAASSSSSSSSTNNNILKTSTKFIYNKPQNQYELLQQQLQLQQEFAQFLTNVANSAATPSSNGSANSTNQRNGGGTIGMGLGMSANSAGGGSGNKNSNGNNGYMPTWSNWFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*.. .*.. .. . *.***** *****.*:*:*::*** *:**:*****:***:************:. :**:****:****:**.****** ***** **:.**********.*:*.::*.*** **:******* *::*. *:********:* **:.*** *** .* .::************.:... * :. * :.. : :: * *:**:* * :*. : * .:.. :*********:*:::*.:***:******* .******: :**************:**.:** ***** **:*********.* ::: ", "identical_positions": 197, "similar_positions": 88, "identity": "28.47%" }, { "cls_id": "homologset.agr.FB:FBgn0010265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62277-1", "uniprot_id": "RS13_HUMAN", "id": "P62277-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62301-1", "uniprot_id": "RS13_MOUSE", "id": "P62301-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62278-1", "uniprot_id": "RS13_RAT", "id": "P62278-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03334-1", "uniprot_id": "RS13_DROME", "id": "Q03334-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGISQSALPYRRTVPSWLKLNADDVKEQIKKLGKKGLTPSKIGIILRDSHGVAQVRFVNGNKILRIMKSVGLKPDIPEDLYHMIKKAVAIRKHLERNRKDKDGKFRLILVESRIHRLARYYKTKSVLPPNWKYESSTASALVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05756-1", "uniprot_id": "RS13_YEAST", "id": "P05756-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.***:*.**:** *..*:*:**.::.* *** * .:******:**::***:***:*.*.:.****:**:** ** *::*****::*****::************.******:***********:* **********:****** ", "identical_positions": 106, "similar_positions": 36, "identity": "70.2%" }, { "cls_id": "homologset.agr.FB:FBgn0010269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31938-1", "uniprot_id": "MP2K1_MOUSE", "id": "P31938-1", "name": "Dual specificity mitogen-activated protein kinase kinase 1", "aln": "--------------------------------------------------------------------------------------------MPKKKPTP--IQLNP-APDGSAVNG--------------------------------TSSAETNLEALQKKLEELELDEQ----------------------------------------------------------------------------------------------------------------QRKRLEAFLTQKQKVGELKD---------------------------------------------------------------------------------------DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFY---SDGEISICMEHMDGGSLDQVLKKAGRIP-------------EQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-----YSVQSDIWSMGLSLVEMAVGRYPIP----PPDAKELELLFG----CHVEGDAAETPPRPRTPGRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSG-VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDA--EEVDFAGWLCSTIGLNQPSTPTHAASI---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01986-1", "uniprot_id": "MP2K1_RAT", "id": "Q01986-1", "name": "Dual specificity mitogen-activated protein kinase kinase 1", "aln": "--------------------------------------------------------------------------------------------MPKKKPTP--IQLNP-APDGSAVNG--------------------------------TSSAETNLEALQKKLEELELDEQ----------------------------------------------------------------------------------------------------------------QRKRLEAFLTQKQKVGELKD---------------------------------------------------------------------------------------DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFY---SDGEISICMEHMDGGSLDQVLKKAGRIP-------------EQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-----YSVQSDIWSMGLSLVEMAVGRYPIP----PPDAKELELLFG----CQVEGDAAETPPRPRTPGRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSG-VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDA--EEVDFAGWLCSTIGLNQPSTPTHAASI---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02750-1", "uniprot_id": "MP2K1_HUMAN", "id": "Q02750-1", "name": "Dual specificity mitogen-activated protein kinase kinase 1", "aln": "--------------------------------------------------------------------------------------------MPKKKPTP--IQLNP-APDGSAVNG--------------------------------TSSAETNLEALQKKLEELELDEQ----------------------------------------------------------------------------------------------------------------QRKRLEAFLTQKQKVGELKD---------------------------------------------------------------------------------------DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFY---SDGEISICMEHMDGGSLDQVLKKAGRIP-------------EQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-----YSVQSDIWSMGLSLVEMAVGRYPIP----PPDAKELELMFG----CQVEGDAAETPPRPRTPGRPLS-SYGMDSRPPMAIFELLDYIVNEPPPKLPSG-VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDA--EEVDFAGWLCSTIGLNQPSTPTHAAGV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63932-1", "uniprot_id": "MP2K2_MOUSE", "id": "Q63932-1", "name": "Dual specificity mitogen-activated protein kinase kinase 2", "aln": "-------------------------------------------------------------------------------------------MLARRKPVLPALTINPTIAEGPSPTS--------------------------------EGASEANLVDLQKKLEELDLDEQ----------------------------------------------------------------------------------------------------------------QRKRLEAFLTQKAKVGELKD---------------------------------------------------------------------------------------DDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKP-AVRNQIIRELQVLHECN-SPYIVGFYGAFY---SDGEISICMEHMDGGSLDQVLKEAKRIP-------------EDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-----YSVQSDIWSMGLSLVELAIGRYPIP----PPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSG-VFSSDFQEFVNKCLIKNPAERADLKLLMNHAFIKRSEG--EEVDFAGWLCRTLRLKQPSTPTRTAV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36506-1", "uniprot_id": "MP2K2_RAT", "id": "P36506-1", "name": "Dual specificity mitogen-activated protein kinase kinase 2", "aln": "-------------------------------------------------------------------------------------------MLARRKPVLPALTINPTIAEGPSPTS--------------------------------EGASEAHLVDLQKKLEELDLDEQ----------------------------------------------------------------------------------------------------------------QRKRLEAFLTQKAKVGELKD---------------------------------------------------------------------------------------DDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKP-AVRNQIIRELQVLHECN-SPYIVGFYGAFY---SDGEISICMEHMDGGSLDQVLKEAKRIP-------------EDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-----YSVQSDIWSMGLSLVELAIGRYPIP----PPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPIS-GHGMDSRPAMAIFELLDYIVNEPPPKLPSG-VFSSDFQEFVNKCLIKNPAERADLKLLTNHAFIKRSEG--EDVDFAGWLCRTLRLKQPSTPTRTAV----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36507-1", "uniprot_id": "MP2K2_HUMAN", "id": "P36507-1", "name": "Dual specificity mitogen-activated protein kinase kinase 2", "aln": "-------------------------------------------------------------------------------------------MLARRKPVLPALTINPTIAEGPSPTS--------------------------------EGASEANLVDLQKKLEELELDEQ----------------------------------------------------------------------------------------------------------------QKKRLEAFLTQKAKVGELKD---------------------------------------------------------------------------------------DDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKP-AIRNQIIRELQVLHECN-SPYIVGFYGAFY---SDGEISICMEHMDGGSLDQVLKEAKRIP-------------EEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTH-----YSVQSDIWSMGLSLVELAVGRYPIP----PPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVS-GHGMDSRPAMAIFELLDYIVNEPPPKLPNG-VFTPDFQEFVNKCLIKNPAERADLKMLTNHTFIKRSEV--EEVDFAGWLCKTLRLNQPGTPTRTAV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24324-1", "uniprot_id": "DSOR1_DROME", "id": "Q24324-1", "name": "Dual specificity mitogen-activated protein kinase kinase dSOR1", "aln": "--------------------------------------------------------------------------------------------MSKNKLNLVLPPVNTEATVAAATVAPTPPFKTPS----------------GTDTHSLLGKPKTSIDALTETLEGLDMGDT----------------------------------------------------------------------------------------------------------------ERKRIKMFLSQKEKIGELSD---------------------------------------------------------------------------------------EDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKP-AIKKQILRELKVLHECN-FPHIVGFYGAFY---SDGEISICMEYMDGGSLDLILKRAGRIP-------------ESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNS-SGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-----YSVQSDIWSLGLSLVEMAIGMYPIP----PPNTATLESIFA---------DNAEESGQP------------TDEPRAMAIFELLDYIVNEPPPKLEHK-IFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAEL--EEVDISGWVCKTMDLP-PSTPKRNTSPN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08018-1", "uniprot_id": "PBS2_YEAST", "id": "P08018-1", "name": "MAP kinase kinase PBS2", "aln": "----------MEDKFANLSLHEKTGKSSIQLNEQTGSDNGSAVKRTSSTSSHYNNINADLHARVKAFQEQRALKRSASVGSNQSEQDKGSSQSPKHIQQIVNKPLPPLPVAGSSKVSQR------------------------MSSQVVQASSKSTLKNVLDNQETQNITDVNINIDTTKITATTIGVNTGLPATDITPSVSNTASATHKAQLLNPNRRAPRRPLSTQHPTRPNVAPHKAPAIINTPKQSLSARRGLKLPPGGMSLKMPTKTAQQPQQFAPSPSNKKHIETLSNSKVVEGKRSNPGSLINGVQSTSTSSSTEGPHDTVGTTPRTGNSNNSSNSGSSGGGGLFANFSKYVDIKSGSLNFAGKLSLSSKGIDFSNGSSSRITLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDE-AKFRQILMELEVLHKCN-SPYIVDFYGAFF---IEGAVYMCMEYMDGGSLDKIYDESSEIGGI----------DEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYP----PETYDN--------------------------------------------IFSQLSAIVDGPPPRLPSD-KFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRN--QDVHMSEYITERLERRNKILRERGENGLSKNVPALHMGGL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06784-1", "uniprot_id": "STE7_YEAST", "id": "P06784-1", "name": "Serine/threonine-protein kinase STE7", "aln": "---MFQRKTLQRRNLKGLNLNLHPDVGNNGQLQEKTETHQGQSRIEGHVMSNINAIQNNSNLFLRRGIKKKLTLDAFGDDQAISKPNTVVIQQPQNEPVLVLSSLSQSPCVSSSSSLSTPCIIDAY----------------SNNFGLSPSSTNSTPSTIQGLSNIATPVEN-------------------------------------------------------------------------------------------------------EHSISLPPLEESLSPAAADLKDTLSGTSN---------------------------------------------------------------------------------GNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINS-KGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNV-----YSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDG----------------------------------------------ILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLIMKYVSPSKDDKFRHWCRKIKSKIKEDKRIKREALDRAKLEKKQSERSTH", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32491-1", "uniprot_id": "MKK2_YEAST", "id": "P32491-1", "name": "MAP kinase kinase MKK2/SSP33", "aln": "MASMFRPPESNRSHQKTPKLTLPVNLVQNAKSTNDGQHLNRSPYSSVNESPYSNNSTSATSTTSSMASNSTLLYNRSSTT--TIKNRPVPPPLPPLVLT-QKKDGIEYRVAGDSQLSERFSNLHVD---ITYKEL-----LSSAPISTKLSNIDTT--FIKKDLDTPEGEDSY-----------------------------------------------------------------------------------------------------PSTLLSAYDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEE------------------------------------------------------------------EAWRFGHLKDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFK-SDYIVQYYGMFTDE-QSSSIYIAMEYMGGKSLEATYKNLLKRGGR---------ISERVIGKIAESVLRGLSYLHER-KVIHRDIKPQNILLNE-KGEIKLCDFGVSGEAVNSLAMTFTGTSFYMAPERIQGQP-----YSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAP------------------------------------------IELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQMK--KKVNMERFVKKCWEKEKDGI----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32490-1", "uniprot_id": "MKK1_YEAST", "id": "P32490-1", "name": "MAP kinase kinase MKK1/SSP32", "aln": "MASLFRPPESAKCNPNSPRLKLP--LLRNNQVDENNIYLTSNGSSTTAYS--SHTPEPLTSSTSTLFSQTRLHPSDSSMTLNTMKKRPAPPSLPSLSINSQSKCKTLPELVPIADVSDGKHDLGLKQRVIAENELSGNSDLTPSSMASPFSHTNTSSPYLRNDLSNSVGSD-------------------------------------------------------------------------------------------------------FSNLISAYEQSSSPIKSSSQPKSSSESYIDLNSVRDVDQLDE------------------------------------------------------------------NGWKYANLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQ-SEYIVRYYGMFTDD-ENSSIYIAMEYMGGRSLDAIYKNLLERGGR---------ISEKVLGKIAEAVLRGLSYLHEK-KVIHRDIKPQNILLNE-NGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQP-----YSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAP------------------------------------------FELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKGQMK--KNVNMEKFVRKCWKD---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .: : . : . . : : : :. :* * * * * :.* * : .*:. **.. :. : *: :** : .. : : **: . **: . . * :. :: .*:.** * . ::***:** *:* . * :*:****** : : *:* : * **:***::. *:: *:**:** ::*:. * :* . :: : : . :: .*:. * * .*. : * : :. .: : ", "identical_positions": 59, "similar_positions": 91, "identity": "7.66%" }, { "cls_id": "homologset.agr.FB:FBgn0010278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08943-1", "uniprot_id": "SSRP1_MOUSE", "id": "Q08943-1", "name": "FACT complex subunit SSRP1", "aln": "MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTG--------KVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVS-QCTTGKNEVTLEFHQNDD----AEVSLMEVRFYVPPTQ----------------------------------EDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARG---TTTTRSFDFEIETKQGT-QYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS------SSSNEGDSDREEKKREQLKRAKMAKDRKSRRKSSE---AKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKRDK---SKKKKKVKAKMEKKSTPSRGSSSK----SSSRQLS-DSFKSKEFVSSDESSSGENKSKKKRRR-SEDS-EEELASTPPSSEDSASGSDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04931-1", "uniprot_id": "SSRP1_RAT", "id": "Q04931-1", "name": "FACT complex subunit SSRP1", "aln": "MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTG--------KVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVS-QCTTGKNEVTLEFHQNDD----AEVSLMEVRFYVPPTQ----------------------------------EDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARG---TTTTRSFDFEIETKQGT-QYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS------SSSNEGDSDREEKKRKQLKRAKMAKDRKSRKKSSE---GKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKRDK---SKKKKKVKAKLEKKSTPSRGSSSK----SSSRQLS-DSFKSKEFVSSDESSSGENKSKKKRRR-SEDSDEEELASTPPSSEDSASGSDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08945-1", "uniprot_id": "SSRP1_HUMAN", "id": "Q08945-1", "name": "FACT complex subunit SSRP1", "aln": "MAETLEFNDVYQEVKGSMNDGRLRLSRQGIIFKNSKTG--------KVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVS-QCTTGKNEVTLEFHQNDD----AEVSLMEVRFYVPPTQ----------------------------------EDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARG---TTTTRSFDFEIETKQGT-QYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGMNPSYDEYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS------SSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVE---VKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDK---SKKKKKVKVKMEKKSTPSRGSSSK----SSSRQLS-ESFKSKEFVSSDESSSGENKSKKKRRR-SEDSEEEELASTPPSSEDSASGSDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NLJ7-1", "uniprot_id": "F6NLJ7_DANRE", "id": "F6NLJ7-1", "name": "FACT complex subunit SSRP1", "aln": "MSDTLEFNEIYQEVKGSWNDGRLRFSKQTVVYKNSKTG--------KVDTIPVPELTQAQWRRVCLGHGIKLWTSTGHIYKYDGFKDADLEKISEYFKDNYKVELTEKDMCVKGWNWGTAKFNGPLLSFDVNDSPTFEIPLSSVS-QCTTGKNEVTVEFHQNDD----TEVSLMEVRFYVPPTTG---------------------------------DEGSDPVEAFAQNVLSKADVIQATGDAVCIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKEETISLTLNMNEDEVERRFEGKLNKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHLRFEEIACVNFARG---TTTTRSFDFEIETKQGN-QYTFSSIEREEYGKLFDFVNAKKLSIKNRGFKEGMKGNDDMYSDSDEDQHDAYLERMKEEGKIREE-GNDS-DDSEGESDESFNPGEEDEDIAEEYDSKASASE-----SSAEEGDSD-EDRKKKSAKKVKFVKERKPRKKE------KKVKDSGAPKRPMSAYMLWLNSSRDRIKSENPGISITEISKKAGEMWKQLGKDKKEEWDGKAEEAKKEYDRAMREYRESGGGSSGSSK---KERKKKRGRNEEKRKRKSGAGREK----EKERSTGNDSFKSREFISSEESSSESDKGKKRKRKGSDNEKEEEAVSTPASSE---SGSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05344-1", "uniprot_id": "SSRP1_DROME", "id": "Q05344-1", "name": "FACT complex subunit Ssrp1", "aln": "MTDSLEYNDINAEVRGVLCSGRLKMTEQNIIFKNTKTG--------KVEQISAEDIDLINSQKFVGTWGLRVFTKGGVLHRFTGFRDSEHEKLGKFIKAAYSQEMVEKEMCVKGWNWGTARFMGSVLSFDKESKTIFEVPLSHVS-QCVTGKNEVTLEFHQNDD----APVGLLEMRFHIPAVE----------------------------------SAEEDPVDKFHQNVMSKASVISASGESIAIFREIQILTPRGRYDIKIFSTFFQLHGKTFDYKIPMDSVLRLFMLPHKDSRQMFFVLSLDPPIKQGQTRYHYLVLLFAPDEETTIELPFSEAELRDKYEGKLEKEISGPVYEVMGKVMKVLIGRKITGPGNFIGHSGTAAVGCSFKAAAGYLYPLERGFIYIHKPPLHIRFEEISSVNFARS---GGSTRSFDFEVTLKNGT-VHIFSSIEKEEYAKLFDYITQKKLHVSNMGKDKSGYKDVDFGDSDNENEPDAYLARLKAEAREKEEDDDDG-DSDEESTDEDFKPNENESDVAEEYDSNVESDSDDDSDASGGGGDSDGAKKKKEKKSEKKEKKEKKHKEKERTKKPSKKKKDSGKPKRATTAFMLWLNDTRESIKRENPGIKVTEIAKKGGEMWKELKD--KSKWEDAAAKDKQRYHDEMRNYKPEAGGDSDNEKGGKSSKKRKTEPSPSKKANTSGSGFKSKEYISDDDSTSSDDEKDNEPAKKKSKPPSDGDAKKKKAK-SESEPEESEEDSNASDEDEEDEASD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04636-1", "uniprot_id": "POB3_YEAST", "id": "Q04636-1", "name": "FACT complex subunit POB3", "aln": "--MSTDFDRIYLNQS--KFSGRFRIADSGLGWKISTSGGSAANQARKPFLLPATELSTVQWSRGCRGYDLKINTKNQGVIQLDGFSQDDYNLIKNDFHRRFNIQVEQREHSLRGWNWGKTDLARNEMVFALNGKPTFEIPYARINNTNLTSKNEVGIEFNIQDEEYQPAGDELVEMRFYIPGVIQTNVDENMTKKEESSNEVVPKKEDGAEGEDVQMAVEEKSMAEAFYEELKEKADIGEVAGDAIVSFQDVFFTTPRGRYDIDIYKNSIRLRGKTYEYKLQHRQIQRIVSLPKADDIHHLLVLAIEPPLRQGQTTYPFLVLQFQKDEETEVQLNLEDEDYEENYKDKLKKQYDAKTHIVLSHVLKGLTDRRVIVPGEYKSKYDQCAVSCSFKANEGYLYPLDNAFFFLTKPTLYIPFSDVSMVNISRAGQTSTSSRTFDLEVVLRSNRGSTTFANISKEEQQLLEQFLKSKNLRVKNEDREVQERLQTALGSDSDEED---------------INMGSAGEDDESVDEDFQVSSDNDADEVAEEFDSDAALS--------DAEGGSDEERPSKKPKVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: : : .**:::: . : :* :.:* * : . :: : .::: *. : : ** : : : : . :: : :: ::: .::*****.. : : * ... **:* : :. *.**** :**: :*: : *:*:**::* . . .: * ::: .**.: ..:*::: *::: ******** *: . ::*:***::**: : *:. **: *. : ::*::::**::**** * :*:* * :* : * :.: : . .::.:* *: .. : ::.:*:* * .*:: **:: .: . .: **:** * ****:..*::: **.::: *.::: **::*. ::*:**:*: :.. *:.*.:** * :::. *:* :.* . . ..:*:: : . . *.. . * .....:: .::***:**.. . *.** .:: . ", "identical_positions": 114, "similar_positions": 209, "identity": "14.65%" }, { "cls_id": "homologset.agr.FB:FBgn0010280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QAP7-1", "uniprot_id": "E9QAP7_MOUSE", "id": "E9QAP7-1", "name": "", "aln": "MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPELRAAAAGALGNHVVSGSPAGAAGAGPAASAEGAPAAAPEPPPAGRARPAGGGPRRPGSSSPRRLLVPAGPAPAPAKLRPLPEASAG---PCPAAAAAAAATAAAVAGPD----PAAAAPPAGPG-------ASKPGPPGPPGPGAAQTLNGSAAPPTAPH-AAPAVSPVNNGPAP------PPAAGSVIQ--------AAPAPAAPSPPAAPAPAAP---PPPAPPAPVAPARPPGHPAAPAPPVSPAAAAAAAAAAAAAQNGAAPAPAAASGGAAGL-GQPGAGAQGAKAEAPKPGPGPGPGPAAAAAAAG--VAGGGA--AGSVLLGPAMPGALPG------PAPGTPAGLAKGAA-AATPSLPRTPAATTGAIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAHAQAQPQSTMAPRPATPTGAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPTTTLQRSPGVQPQLVLGGSAQPASLGTATAVQTGTPQRTVPGASTTSTAATETMENVKKCKSFLSTLIKLASSGKQSTETAANVKDLVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQQPP-ASQATTALTAVVLSSSVQRTAGKTAASVTSALQPPVISLTQPTQVGVGKQAPPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNQLQPVPVVKPTVLPGTKALSTVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEE----SARILATNSELVGTLTRSCKDDTFLLPAPLQRRILEIGKKHGITEL---HPDVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQL-RLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKVDCTGPGSGAEGSGPGAAVPGGSGVGTPRQFTRQRITRVNLRDLIFCLENERE--TSHSLLLYKAFLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K849-1", "uniprot_id": "A0A0G2K849_RAT", "id": "A0A0G2K849-1", "name": "", "aln": "MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPELRAAAAGALGNHVVSGSPAGAAGAGPAASAEGAPAAAPEPPPAG-------------------------PAPAPAKLRPPPEASAG---PCP--VAAAAATAAAAAGPD----PAAAAPPAGPG-------ASKPGPPGPPGPGAAQTLNGSAAPPTAPH-AAPAVSPVNNGPAP------PPAAGSVIQ--------AAPAPAAPSPPAAPAPAAP---PPPAPPAPVAPARPPGHPAAPAPPVSP--AAAAAAAAAAAQNGAAPAPAAASGGAAGL-GQPGAGAQGAKAEAPKPGPGPGPGPAAAAAAAAGGVAGGGA--AGGVLLGPAMPGALPG------PAPGTPAGLAKGAA-AATPSLPRTPAATTGAIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAHAQAQPQSTMAPRPATPTGAAPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPTTTLQRSPGVQPQLVLGGSAQPASLGTATAVQTGTPQRTVTGASTTSTAATETMENVKKCKSFLSTLIKLASSGKQSTETAANVKDLVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQQPP-ASQATTALTAVVLSSSVQRTAGKTAASVTSALQPPVISLTQPTQVGVGKQAPPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNQLQPVPVVKPTVLPGTKALSTVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEE----SARILATNSELVGTLTRSCKDDTFLLPAPLQRRILEIGKKHGITEL---HPDVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQL-RLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKVDCAGPGSGAEGSGPGAAVPGGSGVGTPRQFTRQRITRVNLRDLIFCLENERE--TSHSLLLYKAFLK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00268-1", "uniprot_id": "TAF4_HUMAN", "id": "O00268-1", "name": "Transcription initiation factor TFIID subunit 4", "aln": "MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG--PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEE----SARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITEL---HPDVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQL-RLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKVDCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENERE--TSHSLLLYKAFLK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G5E8Z2-1", "uniprot_id": "TAF4B_MOUSE", "id": "G5E8Z2-1", "name": "Transcription initiation factor TFIID subunit 4B", "aln": "------------------MPAGLTEPAGAAAPVVSSASGAVTMAPVAALPVRVEGTPVALGPVTKAPVSVCVESVAPQPLPAPVGTLVT--------------------------------KVVPVTALPKLG-SPRLPAPQIVTVKTPGTTTIQLPA--------------------------NLQLPPGTVLIKSNSGQLMLVSPQQ---------------------------------------AVTGAKTTSNITPRPAVP---------ANTQTVKICTVPNSSSQLMKKVTVAPVKNLTQIGTTVATTASSTSSGQPVALPSSVITVTPAKLVNTVS-------------------------------TLKSSSLGVLST--------PSNDARLKAETS--VAAQTALPPTVLENVKKCKNFLSMLIKLACSGSQSPE------MGQNVKRLVEQLLDAEIEAEEFTRKLYIELKSAPQPHLVP----------FLKKSVVALRQLLPNSQSFIENCVKEVSGDVVISSCTMTTATSPVVTSTVSP------VLVSGATAPRT-----------LSVQQTLNPLAGPGVANTGVVTLHSVAPAAATGGTTAATVLLQTSKPLTTSVPNTVAAVSLQPENPVVSGAAVTLAIPSATFGEASATPLCLPSAKPAITSAGT--------------------KADKPAIGTPVQI-VTQPSTLLPQAAGIPQTAKVKQLVVQQPSGS----SVNHVTSISHSSPLSTQNCGQK-TPVNAVMPT-----SSIIKQITLPGNKLLS-LQAQRSSIQSNKIKENGPTCFRGEDDINDVTFMAEVNLDEE----NACILAAHSDFVGTLIQSCKEEPFLVIGALQKRILDIGKKHDITEL---NSDAVNLISHATQERLRGLLEKLTTIAQHRMTIYKGSENYILSTDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQL-RLKQKAKELQQLELAQIQYRDANLTALAAIGPRKKRPLE-----SGNESFKDNPSTSGTSSLTATKPFR-PRITRICLRDLIFCMEQERE--MKYSRALYLALLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L4B8-1", "uniprot_id": "A0ABK0L4B8_RAT", "id": "A0ABK0L4B8-1", "name": "", "aln": "------------------MPAGLTGPAGAAAPVVSSASGTVTMAPVAALPVRVESTPVALCPVTKAPVNVCVDSVAPQSLPAPVGTLVT--------------------------------KVVPVTALPKLG-GPRLPAPQIVTVKTPSTTTIQLPA--------------------------NLQLPPGTVLIKSNSGQLMLVSPQQ---------------------------------------AVAGTKTTSTITPRPAVP---------ANTQTVKICTVPNSSSQLMKKVTVAPVKSLTQIGTTVATTASSASSGQPVTVPSNVVTVTPAKPVNNVS-------------------------------ILKSSSLGILST--------PSNDSSLKAETS--VSAQTSLPPTVLENVKKCKNFLSMLIKLACSGSQSPE------MGQNVKKLVEQLLDAEIEAEEFTRKLYIELKSAPQPHLVP----------FLKKSVVALRQLLPNSQSFTENCVQEVSGDVVIPSCAMTTATSPAVTSTVSP------VIVSGAAVPRT-----------LSVQQTLNSLAGPGGANTGVVTLHSVTPATATGGTTATTVLLQTPKPLTTPVPNTVAAVSLQPENPVVSGAAVALAVPSATLGEASAQALCLPSVKTAITSAGT--------------------KAEKAAISTPVQITLAQPGPLLPQSAGIPQAGKAKQLIVQQPSVG----NANHVISISHSSPLSSQTCGQK-APVTAVMPT-----ASIIKQISLPGNKLLS-LQAQTTSIQNNKIKENGPACFRGEDDINDVTCMAEVNLDEE----NACILATHSDFVGKLIQSCKDEPFLLIGALQKRILDIGKKHDITEL---NSDAVNLISHATQERLRGLLEKLTAIAQHRMTIYKGSENYILSTDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQL-RLKQKAKELQQLELAQIQYRDANLTALAAIGPRKKRPLE-----SGNESISKWGATGLTPWLLVFIDLT-SSVRHTLMTSIPDRTPHTAESRMEKGRPAKGAPPP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92750-1", "uniprot_id": "TAF4B_HUMAN", "id": "Q92750-1", "name": "Transcription initiation factor TFIID subunit 4B", "aln": "------------------MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVT--------------------------------KVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPA--------------------------NLQLPPGTVLIKSNSGPLMLVSPQQ---------------------------------------TVTRAETTSNITSRPAVP---------ANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVT-------------------------------TLKPSSLGASST--------PSNEPNLKAENS--AAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPE------MGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVP----------FLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRT-----------VSVQ-TLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGT--------------------TSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGG----NEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILS-LQASPT--QKNRIKENVTSCFRDEDDINDVTSMAGVNLNEE----NACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITEL---NSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCSDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQL-RLKQKAKELQQLELAQIQHRDANLTALAAIGPRKKRPLE-----SGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDLIFCMEQERE--MKYSRALYLALLK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YWV6-1", "uniprot_id": "A0A8M6YWV6_DANRE", "id": "A0A8M6YWV6-1", "name": "", "aln": "----------MSETSVSDKLENDNLRTQTEKKNEAQTNNIENLSETSDKKREVTDLNANVITNRNPDSVSLNEKADPKTEAGSSNAAPQ--------------------------------GPVTVSLLTSSTSASSEAAPKVMVGPAQIKSTTPVVV--------------------------GARVVTSSVQGPGTTS-LALVPQPG---------------------------------------RVSVAISQPRVTTLTTAK---------GPVMTLPRISTPSQGVPMTRAPQTVPLQLPANFQVPQGMVLIRSDSGQLMLVSQQALAQAQGMLPKAAS-------------------------------ANAS---AIVRP--------PSSQATVNTTPI--IRVSLPPTSASATANIKLNPTVGTAVQKPAAATGTAV------FTPSCSAGTTISKPAAVVCTAVR---------KPSSTMGP----------VIKASQMTPNSSTPG--TFNQRTNSVTATTVINTSAGKSVGKGGPSIQSNAPRVVSPNVPPRSSTNTSS-----------TPVTVTAETLENVKKCKNFLVTLMKLASSGTRSANMAQNVRALVKGLLDGKLEAEEFTEKLYMELKSSPQPYLVPFLKRSLPAVRQLTPNSQLFIQQCDHLKPS--------------------DSALTKSTNQKASASVSSSLKNSQPTRTPQLVQTTGVVVKQPQVG----LAAQSQTQSKQMVIQTSTHSTG----------------AVVRQSILQASKTHF-SQPTLP-AQAHSFKDSTSGSFRDDDDINDVASMAGVNLSEE----NARILASGSELVGSVIRSCQEEPFLFPSALQTRVLHIGGSLGVTEV---CPDVLELISLATQERLRDLLEKITAVAQHRQISYRDDWRYTQTNDTRSQLKFLEQLERLEKQKREEEERETLLRIARSRSNSEDPEQQ-RLKQRAKEMQQLELAQMEHRDANLAALAALGPRKKKPLE-----APG--------LGANQLLGSHGHFASRAPVRVTMRDLTFYMEQDPT--FRHTLVLYRAFLG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47825-1", "uniprot_id": "TAF4_DROME", "id": "P47825-1", "name": "Transcription initiation factor TFIID subunit 4", "aln": "-MNTSQTAAGNRITFTSQPLPNGTISIAGNPGAVISTAQLPNTTTIKTIQAGIGGQHQGLQQVHHVQQQQQSQQQQQQQQQTQSAGQPLLNSMLP-------------------------AGVVVGMRQQAPSQQQQKNVPTNPLSRVVINSHMAGVR-------------------------PQSPSITLSTLNTGQTPALLVKTDNG------------------------------------FQLLRVGTTTGPPTVTQTITN---------TSNNSNTTSTTNHPTTTQIRLQTVPAAASMTNTTATSNIIVNSVASSGYANSSQPPHLTQLNAQAPQLP-----------------------------QITQIQTIPAQQSQ--------QQQVNNVSSAGGTATAVSSTTAATTTQQGNTKEKCRKFLANLIELSTREPK-----PVEKNVRTLIQELVNANVEPEEFCDRLERLLNASPQPCLIG----------FLKKSLPLLRQALYTKELVIEGIKPPPQHVLGLAGLSQQLPKIQAQIRPIGPSQTTTIGQTQVRMITPNALGTPRPTIGHTTISKQPPNIRLPTAPRLVNTGGIRTQIPSLQVPGQANIVQIRGPQHAQLQRTGSVQIRATTRPPNSVPTANKLTAVKVGQTQIKAITPSLHPPSLAAISGGPP-------------PTPTLSVLSTLNSASTTTLPIPSLPTVHLPPEALRAREQMQNSLNHNSNHFDAKLVEIKAPSLHPPHMERINASLTPIGAKTMARPPPAINKAIGKKKRDAMEMDAKLNTSSGGAASAANSFFQQSSMSSMYGDDDINDVAAMGGVNLAEE----SQRILG-CTENIGTQIRSCKDEVFLNLPSLQARIRAITSEAGLDEP---SQDVAVLISHACQERLKNIVEKLAVIAEHRIDVIKLDPRYEPAKDVRGQIKFLEELDKAEQKRHEELEREMLLRAAKSRSRVEDPEQA-KMKARAKEMQRAEMEELRQRDANLTALQAIGPRKKLKLDG----ETVSSGAGSSGGGVLSSSGSAPTTLRPRIKRVNLRDMLFYMEQERE--FCRSSMLFKTYLK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50105-1", "uniprot_id": "TAF4_YEAST", "id": "P50105-1", "name": "Transcription initiation factor TFIID subunit 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANSPKKPSDGTGVSASDTPKYQHTVPETKPAFNLSPGKASELSHSLPSPSQIKSTAHVSSTHNDAAGNTDDSVLPKNVSPTT--------------------NLRVESNGDTNNMFSSPAGLALPKKDDKKKN----------------------------------------------------------------KGTSKADSKDGKASNSSGQNAQQQS-----DPNKMQDVLFSAGIDVREEEALLNSSINASKSQVQTNNVKIPNHLPFLHPEQVSNYMRKVGKEQNFNLTPTKNPEILDMMSSACENYMRDILTNAIVISRHRRKAVKINS--GRRSEVSAALRAIALIQKKEEERRVKKRIALGLEKEDYENKIDSEETLHRASNVTAGLRAGSKKQYGWLTSSVNKPTSLGAKSSGKVAS---------------DITARGESGLKFREAREEPGIVMRDLLFALENRRN---SVQTIISKGYAKIRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . . . : . . :: . :.::** . ::: ** . * . :: . : :. ** :. : : . .. : :* * :: ::.:: : :.:: : . .:. . :: : ::: *:::: . :. ... :. * : . : :: . : :.: ::*.:.. : : .: : ", "identical_positions": 13, "similar_positions": 93, "identity": "1.18%" }, { "cls_id": "homologset.agr.FB:FBgn0010282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY96-1", "uniprot_id": "T2FA_RAT", "id": "Q6AY96-1", "name": "General transcription factor IIF subunit 1", "aln": "-------------------------------------------------------------------------------MAALGS-----SSQNVTEY------VVRVPKNTAKRYNIMAFNAADKVN----------FATWNQARLERDLSNKKIYQEEE-MPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKG-----------------------------------------------------------IKKGGVTENTAYYIFTQCADGAFEAFPVQNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQ---DEDEEEKEKRSRKKP-----SELRIHDLEDDLEMS--SDASDAS---GEEGSRASKAKKKAPVTKAGR-----------------------KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSPDEAEGKPKVPQQEDGPKGVDEQSESSEESEEE-KPPEEDKEEEEE-----------------KKAPTPQEKKRRKDSSDDS------DSSE------ESDIDSETSSALFMAKKKTPPKRER-KPSGGSSKGTSRPGTPSAEAASTSSTLRAAASKLEQGKR-----TSETPAAKRLRMDTGPQSLSGKSTP-----------------SSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMIGDKMHFSLKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3THK3-1", "uniprot_id": "T2FA_MOUSE", "id": "Q3THK3-1", "name": "General transcription factor IIF subunit 1", "aln": "-------------------------------------------------------------------------------MAALGS-----SSQNVTEY------VVRVPKNTAKRYNIMAFNAADKVN----------FATWNQARLERDLSNKKIYQEEE-MPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKG-----------------------------------------------------------IKKGGVTENTAYYIFTQCADGAFEAFPVQNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQ---DEDEEEKEKRSRKKP-----SELRIHDLEDDLEMS--SDASDAS---GEEGSRTSKAKKKAPVTKAGR-----------------------KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSPDETEGKPKVPQQEDGPKGVDEQSESSEESEEE-KPPEEDKEEEEE-----------------KKAPTPQEKKRRKDSSDDS------DSSE------ESDIDSETSSALFMAKKKTPPKRER-KPSGGSSKGTSRPGTPSAEAASTSSTLRAAASKLEQGKR-----TSETPAAKRLRMDTGPQSLSGKSTP-----------------SSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMIGDKMHFSLKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35269-1", "uniprot_id": "T2FA_HUMAN", "id": "P35269-1", "name": "General transcription factor IIF subunit 1", "aln": "-------------------------------------------------------------------------------MAALGP-----SSQNVTEY------VVRVPKNTTKKYNIMAFNAADKVN----------FATWNQARLERDLSNKKIYQEEE-MPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKG-----------------------------------------------------------IKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQ---DEDEEEKEKRGRRKA-----SELRIHDLEDDLEMS--SDASDAS---GEEGGRVPKAKKKAPLAKGGR-----------------------KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEE-KPPEEDKEEEEE-----------------KKAPTPQEKKRRKDSSEES------DSSE------ESDIDSEASSALFMAKKKTPPKRER-KPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKR-----VSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTP--------NSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7Y2-1", "uniprot_id": "A0AB32T7Y2_DANRE", "id": "A0AB32T7Y2-1", "name": "Transcription initiation factor IIF subunit alpha", "aln": "-------------------------------------MKATSKTTNHKQVINSTS--------------------YSAVMTSLGSQ--GSSSSSSTEY------VVRVPKNTNKKYSIMAFNAGDKVS----------CSTWTQARMERDMSNRRIYGEEE-TQEGAAGSEFGKKQREEARRKKYGIITKEFKVEDQPWILKVNGKAGRRFKG-----------------------------------------------------------IKKGGVTENASYYIFTQSADGAFEAFPVHAWYNFTPQAKHRTLTAEEAEEEWGRRNKVVNHFSIMLQRRLREQERGGGDEDEEEGEKGAKKKKKGGRGGDLRIHDLEEDLEMS--SDESDGSNGDGEDDEAKAKAKKEK-GAKGKG-----------------------KKKKKKGSDLEGFEDSDDGDFEGLEVDYMSDESSSEEEEPE-KTKPNKGEDVPKGIDEMSESEEESEEETKNEEENKEEEEEEDG--------------KKTPVQVEKKKKKDSSGES------DSSE------DSDIEGEAASALFMVKKRTPPKRGGGRGSAGSSRTGSRPGTPSIDNAATSNTLRAAASKLEQGKRQTTVPSSETPAAKRLKMEPSPQSSSGKSTPQPASGKSTP--------SASDVLLTEDAVRRYLIRKPMTTKDLLKKFQTKRTGLSSEQTVNVLAQILKRLNPERKNINDKMHFYLTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05913-1", "uniprot_id": "T2FA_DROME", "id": "Q05913-1", "name": "General transcription factor IIF subunit 1", "aln": "-------------------------------------MSSASKSTPSAASGSSTS--------------------AAAAAAASVASGSASSSANVQEF------KIRVPK-MPKKHHVMRFNATLNVD----------FAQWRNVKLERENNMKEFRGMEEDQPKFGAGSEYNRDQREEARRKKFGIIARKYRPEAQPWILKVGGKTGKKFKG-----------------------------------------------------------IREGGVGENAAFYVFTHAPDGAIEAYPLTEWYNFQPIQRYKSLSAEEAEQEFGRRKKVMNYFSLMLRKRLRGDEEEEQDPEEAKLIKAATKKS-----KELKITDMDEWIDSEDESDSEDEEDKKKKEQEDSDDGKAKGKGKKGAD-----------------------KKKKKRDVDDEAFEESDDGDEEGREMDYDTSSSEDEPDPEAKVDKDMKGVAEEDALRKLLTSDEEEDDEKKSDESDKEDADGEKKKKDKGKDEVSKDKKKKKPTKDDKKGKSNGSGDSSTDFSSDSTDS-----EDDLSNGPPKKKVVVKDKDKEKEKE-KESAASSKVIASSSNANKSRSATP-TLSTDASKRKMNSLPSDLTASDTSNSPTSTPAKRPKNEISTSLPTSFSGG-----------KVEDYGITEEAVRRYLKRKPLTATELLTKFKNKKTPVSSDRLVETMTKILKKINPVKHTIQGKMYLWIK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41895-1", "uniprot_id": "T2FA_YEAST", "id": "P41895-1", "name": "Transcription initiation factor IIF subunit alpha", "aln": "MSRRNPPGSRNGGGPTNASPFIKRDRMRRNFLRMRMGQNGSNSSSPGVPNGDNSRGSLVKKDDPEYAEEREKMLLQIGVEADAGRSNVKVKDEDPNEYNEFPLRAIPKEDLENMRTHLLKFQSKKKINPVTDFHLPVRLHRKDTRNLQFQLTRAEIVQRQKEISEYKKKAEQERSTPNSGGMNKSGTVSLNNTVKDGSQTPTVDSVTKDNTANGVNSSIPTVTGSSVPPASPTTVSAVESNGLSNGSTSAANGLDGNASTANLANGRPLVTKLEDAGPAEDPTKVGMVKYDGKEVTNEPEFEEGTMDPLADVAPDGGGRAKRGNLRRKTRQLKVLDENAKKLRFEEFYPWVMEDFDGYNTWVGSYEAGNSDSYVLLSVEDDGSFTMIPADKVYKFTARNKYATLTIDEAEKRMDKKSGEVPRWLMKHLDNIGTTTTRYDRTRRKLKAVADQQAMDEDDRDDNSEVELDYDEEFADDEEAPIIDGNEQENKESEQRIKKEMLQANAMGLRDEEAPSENEEDELFGE---------------KKIDEDGERIKKALQKTELAALYSSDENEINPYLSESDIENKENESPVKKEEDSDTLSKSKRSSPKKQQKKATNAHVHKEPTLRVKSIKNCVIILKGDKK-ILKSFPEGEWNPQTTKAVDSSNNASNTVPSPIKQEEGLNSTVAEREETPAPTITEKDIIEAIGDGKVNIKEFGKFIRRKYPGAENKKLMFAIVKKLCRKVGNDHMELKKE------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . *: : . : :: *:: ::. .:: : . .: :: : :* :. :.. :* * : : : . *.. : . . :...* *:.: :.: . . * .: * . . .*:. **:. . ::*: :: :: . : . . : .::: . . . . :. : : * ::* * * :.:::.* .* . *:** . :... : : : :. : : ..::*: ** :: : . : *..: :.*:.. . . :. : * ..: : . . :: . : .. .: ... ..: * . :**. : . : :. .:: . :: * . ...: : .:.: * : : * ", "identical_positions": 35, "similar_positions": 179, "identity": "4.62%" }, { "cls_id": "homologset.agr.FB:FBgn0010288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Y78-1", "uniprot_id": "UCHL3_RAT", "id": "Q91Y78-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMEP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIG---LIHAIANNKDKMHFESGSALKKFLEESVAMSP-EERARHLENYDAIRVTHETSAH---EGQTEAPSIDEKVDLHFIALVHVDGHLYELDGR-KPFPINHG---KTSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15374-1", "uniprot_id": "UCHL3_HUMAN", "id": "P15374-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIG---LIHAIANNKDKMHFESGSTLKKFLEESVSMSP-EERARYLENYDAIRVTHETSAH---EGQTEAPSIDEKVDLHFIALVHVDGHLYELDGR-KPFPINHG---ETSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKB1-1", "uniprot_id": "UCHL3_MOUSE", "id": "Q9JKB1-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMEP-ELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIG---LIHAIANNKDKMHFESGSTLKKFLEESVSMSP-EERAKFLENYDAIRVTHETSAH---EGQTEAPSIDEKVDLHFIALVHVDGHLYELDGR-KPFPINHG---KTSDETLLEDAIEVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58321-1", "uniprot_id": "UCHL4_MOUSE", "id": "P58321-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L4", "aln": "--MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMES-ELLSIIPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGTIGLIHAIANNKDKVHFESGSTLKKFLEESVSMSP-EERAKYLENYDAIRVTHETSAH---EGQTEAPSIDEKVDLHFIALVHVDGHLYELDGW-KPFPINHG---KTSDETLLEDVIKVCKKFMERDPDE---LRFNAIALSAA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0P9-1", "uniprot_id": "UCHL1_MOUSE", "id": "Q9R0P9-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "aln": "-----MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEE-ETLGSVPSPACALLLLFPLTAQHENFRKKQIEELK--GQEVSPKVYFMKQTIGNSCGTIG---LIHAVANNQDKLEFEDGSVLKQFLSETEKLSP-EDRAKCFEKNEAIQAAHDSVAQ---EGQCR---VDDKVNFHFILFNNVDGHLYELDGR-MPFPVNHG---ASSEDSLLQDAAKVCREFTEREQGE---VRFSAVALCKAA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00981-1", "uniprot_id": "UCHL1_RAT", "id": "Q00981-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "aln": "-----MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEE-ETLGSVPSPACALLLLFPLTAQHENFRKKQIEELK--GQEVSPKVYFMKQTIGNSCGTIG---LIHAVANNQDKLEFEDGSVLKQFLSETEKLSP-EDRAKCFEKNEAIQAAHDSVAQ---EGQCR---VDDKVNFHFILFNNVDGHLYELDGR-MPFPVNHG---ASSEDSLLQDAAKVCREFTEREQGE---VRFSAVALCKAA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09936-1", "uniprot_id": "UCHL1_HUMAN", "id": "P09936-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "aln": "-----MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEE-ESLGSVPAPACALLLLFPLTAQHENFRKKQIEELK--GQEVSPKVYFMKQTIGNSCGTIG---LIHAVANNQDKLGFEDGSVLKQFLSETEKMSP-EDRAKCFEKNEAIQAAHDAVAQ---EGQCR---VDDKVNFHFILFNNVDGHLYELDGR-MPFPVNHG---ASSEDTLLKDAAKVCREFTEREQGE---VRFSAVALCKAA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35122-1", "uniprot_id": "UCHL_DROME", "id": "P35122-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "----MLTWTPLESNPEVLTKYIHKLGVSPAWSVTDVIGLED-DTLEWIPRPVKAFILLFPCSETYEKHRAEEHDRIKEVEEQHPEDLFYMRQFTHNACGTVA---LIHSVANNKE-VDIDRG-VLKDFLEKTASLSP-EERGRALEKDEKFTADHEALAQ---EGQTN-AANHEKVIHHFIALVNKEGTLYELDGR-KSFPIKHG---PTSEETFVKDAAKVCKEFMARDPNE---VRFTVLALTAAQQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35127-1", "uniprot_id": "UBL1_YEAST", "id": "P35127-1", "name": "Ubiquitin carboxyl-terminal hydrolase YUH1", "aln": "MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPINEDRKSSTSQQ--------ITSSYDVIWFKQSVKNACGLYA---ILHSLSNNQS--LLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLNVIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLGPNWE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* ***: .: :**: * *: .: : * :* *. *.:**** . : :: . .: :::* *:** . ::*:::**:. :: * *..**.. *. ::* . . : . . .: ** . .. *:* . :* ::**** . *: * :: : : :: .* .: .* :.* :.* ", "identical_positions": 45, "similar_positions": 73, "identity": "18.07%" }, { "cls_id": "homologset.agr.FB:FBgn0010292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80WL2-1", "uniprot_id": "BYST_RAT", "id": "Q80WL2-1", "name": "Bystin", "aln": "MPKLKVTRGARNQERHAPLAEQILAGD-AVRAGTREKRRRHGV------EEEEEYVGPRLSRRILQQARQQQEELETEHATGDRPAKPRERATRLGPGVPQDGSDEEDEEWPTLEKAAKMTVVNHQAE---VVVDPEDERAIEMFMNKNP---PVRRT--LADIIMEKLTEKQTEVETVMSEV--------------SGFPMPQ---LDPRVLEVYRGVREVLCKYRSGILPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRD--DIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIISKCSIPVLHSSAAMLKIAEMEYSGASSIFLRLLLDKKYALPYRVLDALVFHFLAFR---------TEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVE-----------------DVVVTME-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54825-1", "uniprot_id": "BYST_MOUSE", "id": "O54825-1", "name": "Bystin", "aln": "MPKFKVTRGASNREKHAPLAEQILAGN-AVRAGTREKRRGREV------EEEEEYVGPRLSRRILQQARQQQEELETDHGAGDRSAPPRERATRLGPGLPQDGSDEEDEEWPTLEKAAKMAGVDHQAE---VIVDPEDERAIEMFMNKNP---PVRRT--LADIIMEKLTEKQTEVETVMSEV--------------SGFPMPQ---LDPRVLEVYRGVREVLCKYRSGKLPKAFKVIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRD--DIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLAFR---------TEKRQLPVLWHQCLLTLAQRYKADLATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVE-----------------DGGVTME-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13895-1", "uniprot_id": "BYST_HUMAN", "id": "Q13895-1", "name": "Bystin", "aln": "MPKFKAARGVGGQEKHAPLADQILAGN-AVRAGVREKRRGRGTG-----EAEEEYVGPRLSRRILQQARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQDGSDDEDEEWPTLEKAATMTAAGHHAE---VVVDPEDERAIEMFMNKNP---PARRT--LADIIMEKLTEKQTEVETVMSEV--------------SGFPMPQ---LDPRVLEVYRGVREVLSKYRSGKLPKAFKIIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRD--DVAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLHSSAAMLKIAEMEYSGANSIFLRLLLDKKYALPYRVLDALVFHFLGFR---------TEKRELPVLWHQCLLTLVQRYKADLATDQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVE-----------------DVPITVE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51406-1", "uniprot_id": "BYS_DROME", "id": "P51406-1", "name": "Bystin", "aln": "MGKPKKAN--VATIKNVNLEKQITEGR-VAKNKNKDKVK---LR-----AEESANIDARSSQKILAAAKLQQLELDEEN----FPSLVTVKKVNFS---LNDGHVKEDEE---------VNETDLMAD---LDMDEDDVAAFERFQQPAQ---EGKRTLHLSKMIMQKIQEKEADIHTKISDE--------------GSLKIEE---IDPKVKEMYEGVRDVLKRYRSGKIPKAFKIIPKLRNWEQILFITEPHNWSAAAMFQGTRIFCSVLSQAMAQRFYNLVLLPRVRD--DLCEYKKLNMHLYNALKRALFKPAAFMKGIILPLLEGGDCTLREAIIFGSVVARSSIPVLHSSACLLKICEMAYSGANSIFIRYFLDKRYALPYRVVDAAVFHFLRFE---------NDKRELPVLWHQSLLTFAQRYKNDISSEQRDALLQLLKKKSHFKITPDVRRELQAASCRDVEMMETDNGLAGQPAKMYTDADVEYEG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38333-1", "uniprot_id": "ENP1_YEAST", "id": "P38333-1", "name": "Essential nuclear protein 1", "aln": "MARASSTK--ARKQRHDPLLKDLDAAQGTLKKINKKKLAQNDAANHDAANEEDGYIDSKASRKILQLAKEQQDEIEGEELAESERNKQFEARFTTMSYDDEDEDEDEDEEAFGEDISDFEPEGDYKEEEEIVEIDEEDAAMFEQYFKKSDDFNSLSGSYNLADKIMASIREKESQVEDMQDDEPLANEQNTSRGNISSGLKSGEGVALPEKVIKAYTTVGSILKTWTHGKLPKLFKVIPSLRNWQDVIYVTNPEEWSPHVVYEATKLFVSNLTAKESQKFINLILLERFRDNIETSEDHSLNYHIYRAVKKSLYKPSAFFKGFLFPLVETG-CNVREATIAGSVLAKVSVPALHSSAALSYLLRLPFSPPTTVFIKILLDKKYALPYQTVDDCVYYFMRFRILDDGSNGEDATRVLPVIWHKAFLTFAQRYKNDITQDQRDFLLETVRQRGHKDIGPEIRRELLAGASREFVDPQEAN----------DDLMIDVN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :. :: * .:: . . : :.* *. :..: *::** *: ** *:: :. :* .**** . : : :* :* :* : : : *:. ** .: **::::. .: ..: : : :* : * * .:* : * :** **:** * **::::::*:*. *:. .:::.*::* * *. :*:* **:** *.** : .* : ** *:* *:*::*:**.*::**:::** * * *.:*** * **:::: *:*.*****.: : .: :* ..::*:: :***:*****:.:* *::*: *. .* ***:**:.:**:.**** *:: :*:: **: :: : * .: *::**** :. *:. * : : ", "identical_positions": 123, "similar_positions": 151, "identity": "24.75%" }, { "cls_id": "homologset.agr.FB:FBgn0010303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CE90-1", "uniprot_id": "MP2K7_MOUSE", "id": "Q8CE90-1", "name": "Dual specificity mitogen-activated protein kinase kinase 7", "aln": "---MAASSLEQKLSRLEAKLKQENREARRRIDLN------------------LDISP-------QRPRPIIVITLSPAPAPSQRAALQLPLANDGGSRSPSSESSPQ---------------HPTPPT----RPRHMLGLPST---------------LFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMG--FSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYEILEVDVASWFKDVMA---------------------------------------------------------KTESPRTSGVLSQHHLPFFSTSVTWGAWPLAAQTPFQSGVIRCRGRVPSPRRATGGSGGQPCVCA---------------------------------GGPGPSFTEMGPSPSPMLS---------------------------------NTFFTPDPGACPGASTWGLPRRRLCQLLTTSTPGCC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KSH7-1", "uniprot_id": "MP2K7_RAT", "id": "Q4KSH7-1", "name": "Dual specificity mitogen-activated protein kinase kinase 7", "aln": "---MAASSLEQKLSRLEAKLKQENREARRRIDLN------------------LDISP-------QRPRP----------------TLQLPLANDGGSRSPSSESSPQ---------------HPTPPS----RPRHMLGLPST---------------LFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMG--FSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYETLEVDVASWFKDVMA---------------------------------------------------------KTESPRTSGVLSQHHLPFFR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14733-1", "uniprot_id": "MP2K7_HUMAN", "id": "O14733-1", "name": "Dual specificity mitogen-activated protein kinase kinase 7", "aln": "---MAASSLEQKLSRLEAKLKQENREARRRIDLN------------------LDISP-------QRPRP----------------TLQLPLANDGGSRSPSSESSPQ---------------HPTPPA----RPRHMLGLPST---------------LFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMG--FSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKRYETLEVDVASWFKDVMA---------------------------------------------------------KTESPRTSGVLSQPHLPFFR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q23977-1", "uniprot_id": "HEP_DROME", "id": "Q23977-1", "name": "Dual specificity mitogen-activated protein kinase kinase hemipterous", "aln": "MSTIEFETIGSRLQSLEAKLQAQN-ESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDP---KKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRATATGSAIGSGAGSLAGSGSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAGIGDLNRLYRKSPFMQRKLSNGSHHPHYKYNDESPKKESMFSSIGQSILRNLTTSPFSQKKHNSTATTIPLPHNNQTLITDAATAAAAAATATTPPNIAATVLTTTPTTTPTWRLPTENSQAYDSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTESPTLQLTSQQQQQPQRLQPGNQSPIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTSTNPFHSNYVPPPPSTHSTSSQSSTQSTCSQIAINPASISPSSGSGTGNMAGLGIGSAPASGLGAAGHFGAGGTGEQLQYQPLPIAAEATGTSPTLQSRSPEQQSDYGGNGNMVASKLSKLYARRQLLGQSSSSGASNSSLDGCSREQHDAGWFNTLAGAMKRQFATYVKTQLNSTATSPVASSMDRDQEPVHPQPPAYRSVVNNGSGGKSYYYRTLSAASSSSNTSQSTSPTTEPLPGGGTSSFLRRYASSGPGGSISTPPSPHILAGLDRRHRSPDPPPRYNRGQSPLLLRKNLLELSGQPPGSPLLHRRYVSASPPLPPPRRGSESVPGSPQHFRTRIHYTPEPQRRIYRTIDQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: .:*. *****: :* *:: :* *. * *. : * : :* *. ** *.**.**. ***: *. * : *: * ** * * **: **:*** *.*.*::* ::****::**::*.**.*:* ** . .:. :********:** ******************* ***:*:* *: :.**:*.****. * :** * : *:**:****:*** *:** ***:***************:****:*****************:***************** .**.************:******.: **:.*:**********:.*** ** * ** :*:.** .****:*:.**** :** :.**: ** :***..**:.: ** .* .* : ** ", "identical_positions": 242, "similar_positions": 94, "identity": "20.47%" }, { "cls_id": "homologset.agr.FB:FBgn0010309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWZ3-1", "uniprot_id": "A0A0G2JWZ3_RAT", "id": "A0A0G2JWZ3-1", "name": "", "aln": "-------------------MALRLVTHFDVLADVLPSLLVQAATADEGDEG------AETTLGSLRVLNIERNGDIIYTYKDNKGNAVFGIFDCQTRENEHLYTFEKDMQAVSCSVNSERTVLAASFIQYT-EGVRSELQPGSKCLTLLVEIHPVNNVTVLKAVDSCVWVQFLY-PQAESHLLAQNHLLLISEEKYIERFHIQITREDGNRVVIR--------NSSHLPRERIAEDFVWAQWDVSEQRIHYIELQESRSIL---------------------KCVQFWADESFTIMFEMPLDIS-LSGLRFKLVNFGYDYRQDQAKLCHQPSLCIFTNHTGSLCVCYSPKSDSWK------EITYSVFYLHKGYRKTFTVAPGSTDSQVAN--------GVTFLNLGYFVAVYSPCRFLHLLNIRHPDLICHSLFLTGNN-KTAAVLPPSPLQSLPGSLILDCSSGKVYRATLDQSYLMGFLWNAQLDCEKMAALHCALSCDSDPGFP-EQIVQWVSERVSACHSFDLIQEFLIASSYWSVYP----GLDDVDLLLPYSSVLTWD------TEIPG-----MKLVTEELPLPLMK--VYSLKGYWAKLNSNLEYIKY--TKPHLHYHNSVVRREWHNLISEERTGKRRSTMYVRNILDNAVKVISNMEMKTFEPRLIPLLQEE---DRHQRLLMGLMVSELRDHLLRHLQGVEK----------------KKIEQMVLDYISKLLDLVWCLLETSWRKHSVHPWVLHLN------EHGSPADFEVFHLMTRILDAASSLCFPLPPGFHSLHTILGVHCLPLYNLLHYIDNGVLLLTETVVTRLMKDLDNSEKNEKLKFSIIVRLPPLIGQKVCRLWDHPMSSNIISRNHVAQLLKNYKKEPQSSMID--KSSFPVEFLPLNYFIEILMHLESSNQALHGFEGHDNVDAEFVEEAALKHTTSLLGL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TCV3-1", "uniprot_id": "GSAP_MOUSE", "id": "Q3TCV3-1", "name": "Gamma-secretase-activating protein", "aln": "-------------------MALRLVTHFDVLEDVLPSLLTQAATTDEGDRAG----VLETTYGSLRVLNIERNGNIIYTYKDNKGNAVFGLYDCQTRQNEHLYTFEKDMQAVSCSVNSERTVLAASFIQYTTEGVKNDLQPGSKCLTLLVEIHPVNNVKVLKAVDSCVWVQFLY-PQAESHLLPQNHLLLISEEKYIERFHIQITREDGDRVVIR--------NSSHLPRDRLAEDFVWAQWDLSEQRLYYIELKESRSIL---------------------KCIQFRADESFNLMFEMPLDIT-LTGLRFKLVNFGYDYRQDREKLCNQPSLCIFTNHTGSLCMCYSPKSDSRE------EITYSVFYLHKGYRKIFTAAPGSADSQVTNGADSQVTDGIAFLNLGYFVAVYSPGHFLHLLNIQHPDLVCHSLFLTGNN-KIAAVLPPSPLQSLPGSLVLDCYSGKVYRVTLDQSYLLRFLWNAHLDCERMAALHCILSCSQDPGFPEEQIIQWISEHVSACHSFDLIQEFLIASSYWSVYA----ELDDMGMLLQYSSVLTWN------TEIPG-----IKFTTEELPLPLMK--VYGLKGYWAKLNSNLEYIKY--TKPHLHYHNSVVRREWHNLISEERTGKRRSTMYVRNILENAMKVIASMETRTLEPRLIPFLQEE---DRHQRLLMGLMVSELRDHLLRHLQGVEK----------------KKIEQMVLDYISKLLDLIWCLLETSWRKHSMHPLVLHLN------SHCSAADFEVFHLMTRILDAASSLCLPLPPGFHSLHTILGVHCLPLYSLLHYIDNGVLLLTETAVTRLMKDLDNSEKNEQLKFSIIVRLPPLIGQKVCRLWDHPMSSNIISRNHVARLLKNYRKEPRNSMID--KSSFPVEFLPLNYFIEILMGLESSNQALYGFEGHDNVDAEFVEEAALKHTTMLLGL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4D1B5-1", "uniprot_id": "GSAP_HUMAN", "id": "A4D1B5-1", "name": "Gamma-secretase-activating protein", "aln": "-------------------MALRLVADFDLGKDVLPWLRAQRAVSEASGAGSGGADVLENDYESLHVLNVERNGNIIYTYKDDKGNVVFGLYDCQTRQNELLYTFEKDLQVFSCSVNSERTLLAASLVQSTKEGKRNELQPGSKCLTLLVEIHPVNNVKVLKAVDSYIWVQFLY-PHIESHPLPENHLLLISEEKYIEQFRIHVAQEDGNRVVIK--------NSGHLPRDRIAEDFVWAQWDMSEQRLYYIDLKKSRSIL---------------------KCIQFYADESYNLMFEVPLDIS-LSNSGFKLVNFGCDYHQYRDKFSKHLTLCVFTNHTGSLCVCYSPKCASWG------QITYSVFYIHKGHSKTFTTSLENVGSHMTK--------GITFLNLDYYVAVYLPGHFFHLLNVQHPDLICHNLFLTGNN-EMIDMLPHCPLQSLSGSLVLDCCSGKLYRALLSQSSLLQLLQNTCLDCEKMAALHCALYCGQGAQFLEAQIIQWISENVSACHSFDLIQEFIIASSYWSVYS----ETSNMDKLLPHSSVLTWN------TEIPG-----ITLVTEDIALPLMK--VLSFKGYWEKLNSNLEYVKY--AKPHFHYNNSVVRREWHNLISEEKTGKRRSAAYVRNILDNAVKVISNLEARNLGPRLTPLLQEE---DSHQRLLMGLMVSELKDHFLRHLQGVEK----------------KKIEQMVLDYISKLLDLICHIVETNWRKHNLHSWVLHFN------SRGSAAEFAVFHIMTRILEATNSLFLPLPPGFHTLHTILGVQCLPLHNLLHCIDSGVLLLTETAVIRLMKDLDNTEKNEKLKFSIIVRLPPLIGQKICRLWDHPMSSNIISRNHVTRLLQNYKKQPRNSMIN--KSSFSVEFLPLNYFIEILTDIESSNQALYPFEGHDNVDAEFVEEAALKHTAMLLGL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q133-1", "uniprot_id": "A0A8M9Q133_DANRE", "id": "A0A8M9Q133-1", "name": "", "aln": "MSDGVQRTDGVRLVDKLTRHMLRLNPTFDIQRDVVSSILAKEERANIGVLEP-------------RILSVERDGGVVYSWRGATGTTRIGKYDPHSTENKLLYTFDKQVCVSSCSLNKEETLLAVSLSQCTQEGR---FKPVSKCLTLLIEIHPINNTKVLKAVDCKVKVQFLY-PKTCRSTVLESHLLLASEDGYVDQYHIALTRQEGYRVVMQ--------NSERLSRERVAEEFIWVQWDSDTQRIFYLTAR-EKHTL---------------------KCVQFYADRNFETVFELPLEMPNIVTSPVRFVNFGYDHYQDLE--DEGLRLEVFTSPTGTMCVCYSHPVRWHK------DATYTIAFVHQGCSKTFTVSLEQGSAPANFP-----TVRPIFIHLDYYIVVYMPDQFLHLINCRQQDLLCYSLFLSGADGHIEALCSGRAVVSVSGNRLLDVQAGRIYNMDLNPDFLLELLSSGRPEAQQLAALHCMLVYLQPNPVLELKIINWISENVMSFDAFDQIQEFILASLYRISYQ----QCVSLDKLLPYSCVFEKKELPVALTAISG-----VKCTPELLCQPIIKGKAKSLQGYWEELQHVLDRMRYFEAVPCPRFRTSLIKEDWTKLQAAMNSEKKKSPRSHHYIEENTKKVLSMVDTWRLDRRVVPLFQEE---DQQQRVLVGLMVDKLREHLNRHLSRLGK----------------KKIDLLVVNYAAKLLELIWHVLELVWQKLKLGPWVLCIK------QQGNSEEWAMFHVMFRILEATKGLCLPLPPGYSTLLSVLGVRCLPQHTFLQYVDHGLLQLTEPFVSRLMTDLDNSDANEQLKFSILKRLPEHIDKKVSQRWDHPITSASISREYIGSLLDKHSESKDSALLDYSKSSFYPDFLPLNYLAKVLSNRE--EQAQNPFEEQENVDVRFVEETALKQTLIKLGFEVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24118-1", "uniprot_id": "PIGE_DROME", "id": "Q24118-1", "name": "Protein pigeon", "aln": "--------------------MLRQENLAANFCGLLASQGYKEKANEWRILGQ------------EQDGSLLTSWIFEYADEDQRKETCIGHFHATKKQLRLLWTLDNCREIVQATINSSVTLLS---FVEKTEGKLYQAFVVEVRSSEGGTATPLN----SEPSNRQMMTQFLWRVESATRTCWQDKLLVLTHEESIKQYSCVVKQSSTTCSTGGGEGSAWRLDTSILTYETLARNFSWAQWDPECQALYYIHLKPKAKSLSLLDEREEAGEQTTPTLSPTLSAFQFNEKQPTETVLNIPLNLPKLPNGSKEESPSYDDDAVPLRVHDSSLNLIILADTSGMFFVCHYYLYQPMQSEQRDVHFAYSVTLLHHGYVVHCVMPGVPWQKARLLR--------PTFALHGQHHLLVSSAFFVHLLDVGLQHEPNCHIVCAAHN-RSPDITQLVPLR-KWGALAYDAATLDLVSLSVPKSHLIEAFRNDSSLDNRISIIHYFLLHSNDMDVL-AELLNNILERPLSLDTVALLKEALVAGSYAAAVRGLPEDAKPLMRLLPLTTALASRPIHAKVADISVGLSHETLHNTSMMLLSPQQRLSPYRTDIWTRLWDLLNESAK-QEQPRFSAEQVTEKLIFSLACYQPEALSRCTTPLSPDTGTGGFGDYSSGSAFPFSNEVLPFIELEGCTASKQEHVISVYLRELSVHLVKHTSKPNTGFRWLKETFFERSQAPAHVHAVASQFVSAQLELSRALCSLVCRAAGLDARMETSRGFQLIDQMAANQQHSLFLILERYCLAVESIAFPLPEGFSSFFTYLGYRALGYDMFLQYVENHVFELQVDVMKAIVFDIEDSPLGIERKLSLLSALPKQRAQRLLKCWQHPDSLMIRGREHAANILSGQQQEVLHQQRPTACVNQSRNNARSDLTAEALSPLDSFLDLLTAKASLNELDYNLLIETTLSSIDQLKLEA--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .::. : : : .: . . *: .. . :* :. . : . *:*::: ..::*.. *:*: . ** . : *:* :. : : .***: . :.:**: :.: :.:: : :.. . :: *. : :*.:* *.*** . * :.*: : . * ...** .. ::::**::. : . * * :::. :* : :*: . :*:: :*:* . . * . . : . *.**:: . :. :. : . : .: * * : : : . *: : . :::: :* * . . :::: : *. : .:. ::* ::*. * : ** : .: : *. .. : . : . * .* *: * . : : .: .: :. . : . : .: *::: * :*. ::.: : :* *: :* . . ::. :. :: : *:* : . : : . : . . : :* :: * *...: :*** *: :: : ** :.* :*: :: :: * : :: *:::: . : *:*:: ** ::: : *:** : .*:: :*. :. . : : : * : : :::* .:: *::*. ", "identical_positions": 93, "similar_positions": 272, "identity": "9.61%" }, { "cls_id": "homologset.agr.FB:FBgn0010314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACB4-1", "uniprot_id": "A0A8I6ACB4_RAT", "id": "A0A8I6ACB4-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "--------------------MVH--KQIYYSDKYFDEQYEYWHVMLPRELSKQVLKTHL---------MSEEEWRRLGVQQSLGWAHDMIHEPEPHSLLFRRPL------------PKEQQK----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZGT4-1", "uniprot_id": "D3ZGT4_RAT", "id": "D3ZGT4-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "--------------------MVH--KQIYYSDKYFNKHYEYWHVMLPRELSKQVPKTHL---------MSEEEWRRLGVQKNLGWVHYMIHEPEPHILLFRQPL------------PKEQQK----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33552-1", "uniprot_id": "CKS2_HUMAN", "id": "P33552-1", "name": "Cyclin-dependent kinases regulatory subunit 2", "aln": "--------------------MAH--KQIYYSDKYFDEHYEYRHVMLPRELSKQVPKTHL---------MSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPL------------PKDQQK----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56390-1", "uniprot_id": "CKS2_MOUSE", "id": "P56390-1", "name": "Cyclin-dependent kinases regulatory subunit 2", "aln": "--------------------MAH--KQIYYSDKYFDEHYEYRHVMLPRELSKQVPKTHL---------MSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPL------------PKEQQK----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61025-1", "uniprot_id": "CKS1_MOUSE", "id": "P61025-1", "name": "Cyclin-dependent kinases regulatory subunit 1", "aln": "--------------------MSH--KQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHL---------MSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPL------------PKKPKK----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61024-1", "uniprot_id": "CKS1_HUMAN", "id": "P61024-1", "name": "Cyclin-dependent kinases regulatory subunit 1", "aln": "--------------------MSH--KQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHL---------MSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPL------------PKKPKK----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M990-1", "uniprot_id": "F1M990_RAT", "id": "F1M990-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "--------------------MSH--KQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHL---------MFESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPL------------PKKPKK----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24152-1", "uniprot_id": "CKS1_DROME", "id": "Q24152-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "---------------------MS--KDIYYSDKYYDEQFEYRHVVLPKELVKMVPKTHL---------MTEAEWRSIGVQQSRGWIHYMIHKPEPHILLFRR--------------PKTD------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q1LX17-1", "uniprot_id": "Q1LX17_DANRE", "id": "Q1LX17-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "--------------------MSSGKKQIYYSDKYSDEEYEYRHVMLPKQLSKLVPSSHL---------MSEEEWRGLGVQQSQGWIHYMIHKPEPHILLFRRPL------------PKE-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20486-1", "uniprot_id": "CKS1_YEAST", "id": "P20486-1", "name": "Cyclin-dependent kinases regulatory subunit", "aln": "MYHHYHAFQGRKLTDQERARVLEFQDSIHYSPRYSDDNYEYRHVMLPKAMLKVIPSDYFNSEVGTLRILTEDEWRGLGITQSLGWEHYECHAPEPHILLFKRPLNYEAELRAATAAAQQQQQQQQQQQQQQQQHQTQSISNDMQVPPQIS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*:** :* :..:** **:**: : * : . :: : * *** :*: :. ** * * **** ***:: .: ", "identical_positions": 27, "similar_positions": 24, "identity": "18.0%" }, { "cls_id": "homologset.agr.FB:FBgn0010315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P39948-1", "uniprot_id": "CCND1_RAT", "id": "P39948-1", "name": "G1/S-specific cyclin-D1", "aln": "---------------------------------------------------------------------------------------------------------------MEHQLLCCEVETIR-RAYPDT------------NLL-NDRVLRAMLKTEETCAPSVSYFKCVQREIVPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKET--IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADE-----NKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTTHFLSRVIKCDPDCLRACQEQ-IEALLESS-------------------------------------------------LRQAQQNIDPKA-TEEEGEVEEEAGLACTPTDVRDVDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25322-1", "uniprot_id": "CCND1_MOUSE", "id": "P25322-1", "name": "G1/S-specific cyclin-D1", "aln": "---------------------------------------------------------------------------------------------------------------MEHQLLCCEVETIR-RAYPDT------------NLL-NDRVLRAMLKTEETCAPSVSYFKCVQKEIVPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKET--IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADE-----NKQTIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTTHFLSRVIKCDPDCLRACQEQ-IEALLESS-------------------------------------------------LRQAQQNVDPKA-TEEEGEVEEEAGLACTPTDVRDVDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24385-1", "uniprot_id": "CCND1_HUMAN", "id": "P24385-1", "name": "G1/S-specific cyclin-D1", "aln": "---------------------------------------------------------------------------------------------------------------MEHQLLCCEVETIR-RAYPDA------------NLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKET--IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEE-----NKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQ-IEALLESS-------------------------------------------------LRQAQQNMDPKA-AEEEEEEEEEVDLACTPTDVRDVDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90459-1", "uniprot_id": "CCND1_DANRE", "id": "Q90459-1", "name": "G1/S-specific cyclin-D1", "aln": "---------------------------------------------------------------------------------------------------------------MEHQLFCCEVDTIR-RAYQDS------------NLL-NDRVLQTMLKAEENYLPSPNYFKCVQKEIVPKMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSVEPTKKTRLQLLGATCMFLASKMKET--VPLTAEKLCIYTDNSVRPGELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQS-----SKQILRKHAQTFVALCATDVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLTNFLSQVIRSDPDCLRSCQEQ-IESLLESS-------------------------------------------------LRQAQQHIS-----TETKRVEEDVDLSCTPTDVRDINI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LVJ6-1", "uniprot_id": "A0ABK0LVJ6_RAT", "id": "A0ABK0LVJ6-1", "name": "G1/S-specific cyclin-D2", "aln": "-------------------------------------------------------------------------------------------------------MSGPSGDRLAMELLCCEVDPVR-RAVPDR------------NLL-EDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKET--IPLTAEKLCIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKE-----KLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVNALTCDALTELLAKITHTDVDCLKACQEQ-IEAVLLNS-------------------------------------------------LQQFRQEQHN------GSKSVEDPDQATTPTDVRDVDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30280-1", "uniprot_id": "CCND2_MOUSE", "id": "P30280-1", "name": "G1/S-specific cyclin-D2", "aln": "-----------------------------------------------------------------------------------------------------------------MELLCCEVDPVR-RAVPDR------------NLL-EDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKET--IPLTAEKLCIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKE-----KLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDDEVNTLTCDALTELLAKITHTDVDCLKACQEQ-IEALLLNS-------------------------------------------------LQQFRQEQHNA-----GSKSVEDPDQATTPTDVRDVDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30279-1", "uniprot_id": "CCND2_HUMAN", "id": "P30279-1", "name": "G1/S-specific cyclin-D2", "aln": "-----------------------------------------------------------------------------------------------------------------MELLCHEVDPVR-RAVRDR------------NLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKET--SPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQRE-----KLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQ-IEAVLLNS-------------------------------------------------LQQYRQDQRD------GSKSEDELDQASTPTDVRDIDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48961-1", "uniprot_id": "CCND3_RAT", "id": "P48961-1", "name": "G1/S-specific cyclin-D3", "aln": "-----------------------------------------------------------------------------------------------------------------MELLCCEGTRLAPRAGPDP------------RLLGDQRVLQSLLRLEERYVPRGSYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRET--TPLTIEKLCIYTDQAMAPWQLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSD-----RQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVLGLG----ACSMSADELTELLAGITGTEVDCLRACQEQQIEAALRES-------------------------------------------------LREAAQTAPSPVPKAPGGSSSQGPSQTSTPTDVTAIHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30282-1", "uniprot_id": "CCND3_MOUSE", "id": "P30282-1", "name": "G1/S-specific cyclin-D3", "aln": "-----------------------------------------------------------------------------------------------------------------MELLCCEGTRHAPRAGPDP------------RLLGDQRVLQSLLRLEERYVPRASYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRET--TPLTIEKLCIYTDQAVAPWQLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSD-----RQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVLGLG----ACSMSADELTELLAGITGTEVDCLRACQEQ-IEAALRES-------------------------------------------------LREAAQTAPSPVPKAPRGSSSQGPSQTSTPTDVTAIHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30281-1", "uniprot_id": "CCND3_HUMAN", "id": "P30281-1", "name": "G1/S-specific cyclin-D3", "aln": "-----------------------------------------------------------------------------------------------------------------MELLCCEGTRHAPRAGPDP------------RLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRET--TPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRD-----RQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTELLAGITGTEVDCLRACQEQ-IEAALRES-------------------------------------------------LREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KUZ5-1", "uniprot_id": "Q7KUZ5_DROME", "id": "Q7KUZ5-1", "name": "", "aln": "MDLLCSEIIVYESDPSLYRLNKRQQQMSSPAIIRDQSSICSSLGDAESDSHPDAQNNAVVCNMKELVYIYASVDSAAKNPEQLEPPPPPPPPPPPPPTATQSIQSYPRYISQEPPTSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHN-LHFLLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLPKAPAECVEQHQQQHNFGSAAPHRTHTCKMQAQAQAQNEIQDVTF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * .:* *. :* ** . : .:*::: * **:::* **:*** *:.*:*:*. **:**:**:*: . *::**:*.:.*:::***::*. .*: : * :***::: :* . *: :.:* *:*::: . **: :: ::. . :: ***:*::*.*.: .* ..* :*:.*: *:: ** ::: : : :: * : : * :.: * . : : .:: : :", "identical_positions": 65, "similar_positions": 101, "identity": "13.6%" }, { "cls_id": "homologset.agr.FB:FBgn0010317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LPN6-1", "uniprot_id": "F1LPN6_RAT", "id": "F1LPN6-1", "name": "Cyclin-J-like protein", "aln": "MREARPPIPRAREGGPRRPELRAAAGPSAGRGAPVAGRDGLRRRRSRAREARGRAATGGHYVPGAGRDPPPADPHSGTAMRESLPGSRGAPQDPDSLISAAVMDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSRHCHLCPSARHLAIYLLDHFMDQYNVTTSKQLYTVAVSCLLLAS------------------------------------------------KFEDREDRVPKLDQINSTRILSSHNFSLTKKELLTTELLLLEAFSWDLCLPTPAHFLDYYLLASISQKDHHCHTWPTTCLRKTKECLKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRVSNYSLEHLSTCIEILLVAYDNVLKDAVAVKSQALAMVPSSSSAPTQVLFQPPTYPSLSQPPPTTLAQFQSPAQDLCLAYRDSLQAHRSGTLLSGDTGPS---LHTPYPTLQPLDMCPVPVPASLSMQMAIAAEPRHCLTATYGSSYFSGSHM-FPTGCFDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SRT8-1", "uniprot_id": "CCNJL_MOUSE", "id": "Q5SRT8-1", "name": "Cyclin-J-like protein", "aln": "------------------------------------------------------------------------------------------------------MDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSRHCHLCPSARHLAIYLLDHFMDQYNITTSKQLYTVAVSCLLLAS------------------------------------------------KFEDREDRVPKLEQINNTRILSSQNFSLTKKELLTTELLLLEAFSWDLCLPTPAHFLDYYLLASISQKDHHCHAWPTTCLRKTKECLKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRVSSYSLEHLSTCIEILLVAYDNVLKDAVAVKSQTLAMVPGSSSAPAQVLFQPPTYPTLSQPPPTTLAQFQSPAQDLCLAYRDSLQAHRSGGLLSGDTGPS---LHTPYPTLQPLDMCPVPVPASLSMQMAIAAEPRHCLTASYGSSYFSGSHM-FPAGCFDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV13-1", "uniprot_id": "CCNJL_HUMAN", "id": "Q8IV13-1", "name": "Cyclin-J-like protein", "aln": "-----------------------------------------------------------------------------------------------------MMDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSSHCQLCPAARHLAVYLLDHFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSSNSPASAPHPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVYDNVLKDAVAVKSQALAMVPGTPPTPTQVLFQPPAYPALGQP-ATTLAQFQTPVQDLCLAYRDSLQAHRSGSLLSGSTGSS---LHTPYQPLQPLDMCPVPVPASLSMHMAIAAEPRHCLATTYGSSYFSGSHM-FPTGCFDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5T5M9-1", "uniprot_id": "CCNJ_HUMAN", "id": "Q5T5M9-1", "name": "Cyclin-J", "aln": "----------------------------------------------------------------------------------------------------MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDIS-IQQLHLVALSCLLLAS------------------------------------------------KFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDG-WPMICLEKTKLYMAKYADYFLEVSLQ-----------VAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQS--AQLSVFQTASQPSRPVHFQQP------QYLHQTHQTSLQYRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINEHYPCITPCFER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TZI6-1", "uniprot_id": "CCNJ_MOUSE", "id": "Q3TZI6-1", "name": "Cyclin-J", "aln": "----------------------------------------------------------------------------------------------------MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLNLRRYFADLIAIVSNRFTLCPPARHLAVYLLDLFMDRYDIS-IQQLHLVALSCLLLAS------------------------------------------------KFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQTLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDG-WPMVCLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLLAHDNDVKEANKQRGQSAPQS--TQLTVFQTA-QPSRPVHFQQP------QYLHQS---SLQYRHPVSEQPSRQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINEHFPCITPCFER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VZP3-1", "uniprot_id": "Q9VZP3_DROME", "id": "Q9VZP3-1", "name": "", "aln": "-------------------------------------------------------------------------MEQKVAAEQNIFVVDRKLKKTCPQADVERLAKTHWLTDYARDIFLTMREQELSRRPLFYLSPQLNERRRMLQLLKLATSAHKLSRCALHLAVYYMDRFVDYYKIR-PDKLLLVAITCLHIAA------------------------------------------------QIENTDAFIPRYSEMN--RLVKN---AYTAFEYKAVERKILCFLNFELIRPTTASFVELFACSFLTRSDFKNY----------IEMLDEYERNHHTQPYQRYISFEEMLSILAQLLLRMADYTLYISRFANDLPSLLAAACIAAVRQVSGVRRWSEYLVGLTSYTEANVEPYMNVLTDYYYYHVIQTDYGSPSVQTN-----QSLASPDSGFEESFTENTNLVVSDEVVTVETYNIIT-VQLQDPSPHSSTFLPKEQTNLKRSRFEDDTENQHPLKHAKVESVAKD------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *:. ::* :**. . ** *. ** : ::: : : *. * ***:* :* *:* *.: .:* **::** :* ::*: : :*: .::* :.. * * :* :.::* **.* *:: : : ..* : : :* . . * :* : : * :* :: . : : . : :. . . : . . * : * :: :. : .* : * : * . ", "identical_positions": 49, "similar_positions": 83, "identity": "9.06%" }, { "cls_id": "homologset.agr.FB:FBgn0010323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7E7-1", "uniprot_id": "G3V7E7_RAT", "id": "G3V7E7-1", "name": "Homeobox protein goosecoid", "aln": "----------------------------------------------------------------------------------------------------MPASMFSIDNILAARPR----------------------CKDAVLPVAPSAAAPVVFPALHGDSLYGAGGGTSSDYGAFYPRPVAPGGAGLPAAVGGSRLGYNSYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQ-LHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEV------WFKNRRAKWRRQKR---------------SSSEESENAEKWNKTSS-----------------KASPEKREEEGKSDLDSDS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02591-1", "uniprot_id": "GSC_MOUSE", "id": "Q02591-1", "name": "Homeobox protein goosecoid", "aln": "----------------------------------------------------------------------------------------------------MPASMFSIDNILAARPR----------------------CKDAVLPVAPSAAAPVVFPALHGDSLYGAGGGTSSDYGAFYPRPVAPGGAGLPAAVGSSRLGYNSYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQ-LHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEV------WFKNRRAKWRRQKR---------------SSSEESENAEKWNKTSS-----------------KASPEKREEEGKSDLDSDS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56915-1", "uniprot_id": "GSC_HUMAN", "id": "P56915-1", "name": "Homeobox protein goosecoid", "aln": "----------------------------------------------------------------------------------------------------MPASMFSIDNILAARPR----------------------CKDSVLPVAHSAAAPVVFPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLPAAVSGSRLGYNNYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQ-LHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEV------WFKNRRAKWRRQKR---------------SSSEESENAEKWNKTSSS----------------KASPEKREEEGKSDLDSDS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53544-1", "uniprot_id": "GSC_DANRE", "id": "P53544-1", "name": "Homeobox protein goosecoid", "aln": "----------------------------------------------------------------------------------------------------MPAGMFSIDSILAGRPS----------------------CKDSVLLHRN---APVVFSNLT-ESLYTAAG----DFNGLYSHTGPP-APNLQSVNG--RIGYNNYYYGQLHVQG-PTGPACCGAIPTLGSQQCPCIPT--GYDSAGSVLISPVPHQMMSYMNVGTLSRTELQLLNQ-LHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEV------WFKNRRAKWRRQKR---------------SSSEESENSQKWNKSTK------------------TTSEKIEE-GKSDVDSDS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54366-1", "uniprot_id": "GSC_DROME", "id": "P54366-1", "name": "Homeobox protein goosecoid", "aln": "MVETNSPPAGYTLKRSPSDLGEQQQPPRQISRSPGNTAAYHLTTAMLLNSQQCGYLGQRLQSVLQQQHAQHQQSQSQTPSSDDGSQSGVTILEEERRGGAAAASLFTIDSILGSRQQGGGTAPSQGSHISSNGNQNGLTSNGISLGLKRSGAESPASPNSNSSSSAAASPIRPQRVPAMLQHPGLHLGHLAAAAASGFAASPSDFLVAYPNFYPNYMHAAAVAHVAAA-QMQAHVSGAAAGLSGHGHHPHHPHGHPHHPHLGAHHHGQHHLSHLGHGPPPKRKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEV------WFKNRRAKWRKQKREEQERLRKLQEEQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGSDHYSAQLVHIKSDANGYSDADESSDLEVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0L7J8-1", "uniprot_id": "A0ABK0L7J8_RAT", "id": "A0ABK0L7J8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MYILRLLRRPPAGMATAGSAASHRDPGRPCPFSIEHILSSLPERRPVAR---PPQPVGGRNPAE--PDEPEAPAPAAPCACCCCCNPRAAPRGTPETASGPGLRLGWPLRLAPESPSPLTAPSTGSPALTGTSGPGP---QRRTRRHRTIFSEEQLQALEALFVQNQYPDVGTRERLAVRIRLREERVEVGVPPAAWRPTPAPPLLFQRPTFR----------WCFTCRLLHWRETSQPHPMITR--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56916-1", "uniprot_id": "GSC2_MOUSE", "id": "P56916-1", "name": "Homeobox protein goosecoid-2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MATAGSAASRRDPGRPCPFSIEHILSSLPERRPATR---PPQPVGGRNPAE--LDEPEAPVPAAPCACCCCCNPRAATRGTPETSSGPGLRLAWPLRLAPATPSPLTAPRAGSPALTGTSGPGP---QRRTRRHRTIFSEEQLQALEALFVQNQYPDVGTRERLAVRIRLREERVEV------WFKNRRAKWRHQKRAS--------------SSRLLPGTKKTPKESC-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15499-1", "uniprot_id": "GSC2_HUMAN", "id": "O15499-1", "name": "Homeobox protein goosecoid-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MAAAAGGAASRRGAGRPCPFSIEHILSSLPERSLPARAACPPQPAGRQSPAK--PEEPGAP-EAAPCACCCCCGPRAAPCGPPEAAAGLGARLAWPLRLGPAVPLSLGAPAGGSGALPGAVGPGS---QRRTRRHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEV------WFKNRRAKWRHQKRAS-------------ASARLLPGVKKSPKGSC-----------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . . . . ... . : * * . . :*.*******::***: ** * :.:**** **:** :: *:**:*** * . . *: : . .. . ", "identical_positions": 32, "similar_positions": 36, "identity": "7.58%" }, { "cls_id": "homologset.agr.FB:FBgn0010328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AEP0-1", "uniprot_id": "A0A8I6AEP0_RAT", "id": "A0A8I6AEP0-1", "name": "", "aln": "-------------------------------------------------------------------------MDTSSVGTLELTDQSPVLLGSTAMATSLTNVGNSFSGPPNPLVSRSSKFQNSSVEDDDDVVFIEPVQPPPSSAPLVADQRPITFTSSKNEELQGNDPKILPSSKELAPQKGSVSETIVIDDEEDMETNQGQEKNSSNFIERRPSETKNRTNDVDFSSSTFSRSKVNAGMSNSGITTEPDSEIQIANVTTLETGVSSVSDGQLESTDGRDMNLMITHVTSLHNTSLGDSSNGLQSSNFGVNIQTYTPSLTSQTKTGVG-PFNPGRMNVAGDVFQNGESAPHHNPDSWISQSAS--------------FPRNQKQQGVDSLSPVASLPKQ----NFQPSNQQ---PTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHK------PAPKKLCVMCKKDITTMKGTIVAQVDSSESFQE----------FCSTSCLSLYEDKQS-----------------------------------PAKG-ALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRM---------------------------------------------ANGLIMNCCEQCGEYLPSK--GAGNNVLVIDGQQKRFCCQSCVSEYKQVG------------------SHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPS-------------------------------------------------------DIQLKCNYCKNSFCSKPEILEWENKVHQFCSRTCSDDYKKLHCI----VTYCEYCQ-EEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLG-LRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQEWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNM----------------------------TTQKGPENLHYDQGCQT-----SRTKMTG--------------------------SAPPPSPTPNKEMKNKAILCKPLTMTKATYCKPHMQTKSCQTD--ENWKTEYVPVPIPVPVYVPVPMHMYSQSIPVPTTVPVPVPVPVFLPAPLENSEKIPASVEDLKSKVSSDPLDTELLTMTDMMTEEEGKTEASN---------------------INSVIIETDIIGSDLTKNSDSDIQSN---MPDVPYEPDLDIEIDFPR--EELDMENEFLLPP-VFG--EEYEEQPRPRSKKKGTKRKAVSGYQSHDDSSDNSECSFP---------------------FKYTYGVNAWKHWVKTRQLDEDLLELDELKS--------------------------------SKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQMFEQELNKILRSWQPSILPDGSIFS-RVEEDYLWRIKQLGSHSPVALLN----TLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVS---------------------------SLCGTDNEDKIATGKRKHEDDEPVFEQVENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSASLDRN--TLENMLVRVLLVKDIYDKDNYELDEDTD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CU65-1", "uniprot_id": "ZMYM2_MOUSE", "id": "Q9CU65-1", "name": "Zinc finger MYM-type protein 2", "aln": "-------------------------------------------------------------------------MDTSSVGTLELTDQTPVLLGSTAMATSLTNVGNSFSGPPNPLVSRSSKFQNSSVEDDDDVVFIEPVQPPPSSAPLVADQRPITFTSSKNEELQGNDPKILPSSKELAPQKGSVSETIVIDDEEDMETNQGQEKSSSNFIERRPSETKNRTNDVDFSSSTFSRSKVNAGVSNSGITTEPDSEIQIANVTTLETGVSSVSDGQLESTDGRDMNLMITHVTSLHNTSLGDGSNGLQSSNFGVNIQTYTPSLTSQTKAGVG-PFNPGRMNVAGDVFQNGESAPHHNPDSWISQSAS--------------FPRNQKQQGVDSLSPVASLPKQ----IFQPSNQQ---PTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHK------PAPKKLCVMCKKDITTMKGTIVAQVDSSESFQE----------FCSTSCLSLYEDKQS-----------------------------------PAKG-ALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRM---------------------------------------------ANGLIMNCCEQCGEYLPSK--GAGNNVLVVDGQQKRFCCQSCVTEYKQVG------------------SHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPS-------------------------------------------------------DIQLKCNYCKNSFCSKPEILEWENKVHQFCSKTCSDDYKKLHCI----VTYCEYCQ-EEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLG-LRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQEWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNM----------------------------TTQKGPENLHYDQGCQT-----SRTKMTG--------------------------SAPPPSPTPNKEMKNKAILCKPLTMTKATYCKPHMQTKSCQTD--ENWKTEYVPVPIPVPVYVPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPATVEDLKSKVSSDPLDSELLTMTDMMTEEEGKAEASN---------------------INSVIIETDIIGSDLTKNSDPDIQSN---MPDVPYEPDLDIEIDFPRAAEELDMENEFLLPP-VFG--EEYEEQPRPRSKKKGTKRKAVSGYQSHDDSSDNSECSFP---------------------FKYTYGVNAWKHWVKTRQLDEDLLVLDELKS--------------------------------SKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQMFEQELNKILRSWQPSILPDGSIFS-RVEEDYLWRIKQLGSHSPVALLN----TLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVS---------------------------SLCGTDNEDKIATGKRKHEDDEPVFEQVENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRN--TLENMLVRVLLVKDIYDKDNYELDEDTD---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBW7-1", "uniprot_id": "ZMYM2_HUMAN", "id": "Q9UBW7-1", "name": "Zinc finger MYM-type protein 2", "aln": "-------------------------------------------------------------------------MDTSSVGGLELTDQTPVLLGSTAMATSLTNVGNSFSGPANPLVSRSNKFQNSSVEDDDDVVFIEPVQPPPPSVPVVADQRTITFTSSKNEELQGNDSKITPSSKELASQKGSVSETIVIDDEEDMETNQGQEKNSSNFIERRPPETKNRTNDVDFSTSSFSRSKVNAGMGNSGITTEPDSEIQIANVTTLETGVSSVNDGQLENTDGRDMNLMITHVTSLQNTNLGDVSNGLQSSNFGVNIQTYTPSLTSQTKTGVG-PFNPGRMNVAGDVFQNGESATHHNPDSWISQSAS--------------FPRNQKQPGVDSLSPVASLPKQ----IFQPSVQQQ--PTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHK------PAPKKLCVMCKKDITTMKGTIVAQVDSSESFQE----------FCSTSCLSLYEDKQN-----------------------------------PTKG-ALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRM---------------------------------------------ANGLIMNCCEQCGEYLPSK--GAGNNVLVIDGQQKRFCCQSCVSEYKQVG------------------SHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPS-------------------------------------------------------DIQLKCNYCKNSFCSKPEILEWENKVHQFCSKTCSDDYKKLHCI----VTYCEYCQ-EEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLG-LRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQDWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNM----------------------------TTQKGPENLHYDQGCQT-----SRTKMTG--------------------------SAPPPSPTPNKEMKNKAVLCKPLTMTKATYCKPHMQTKSCQTD--DTWRTEYVPVPIPVPVYIPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPAAIEELKSKVSSDALDTELLTMTDMMSEDEGKTETTN---------------------INSVIIETDIIGSDLLKNSDPETQSS---MPDVPYEPDLDIEIDFPRAAEELDMENEFLLPP-VFG--EEYEEQPRPRSKKKGAKRKAVSGYQSHDDSSDNSECSFP---------------------FKYTYGVNAWKHWVKTRQLDEDLLVLDELKS--------------------------------SKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQTFEQELNKILRSWQPSILPDGSIFS-RVEEDYLWRIKQLGSHSPVALLN----TLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVS---------------------------SLCGTDNEDKITTGKRKHEDDEPVFEQIENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRN--TLENMLVRVLLVKDIYDKDNYELDEDTD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A895-1", "uniprot_id": "A0A8I6A895_RAT", "id": "A0A8I6A895-1", "name": "", "aln": "-------------------------------------------------------------------------MDPSDFP----SPFDPLTLPEKPLAGDLP-VDMEFG--EDLLESQTAPTRG-----------WAPPGPSPSSGALDLLDTPSGLEKDPGVVLDGATELLGLGG---LLYKAPSPPEVDHGSEGTLAWDSGEQTLEPGPGCQTPEVMP---PDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEEISPLATSRRGSPGQEEEHTQGQPQSPNAPPSPSVGET-LGDGINSSQT-KPGVSNPAAHPSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSD--------EDSDAMVDDPNDEDFVPFRPRRSPRMS----LRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKK------PLGRKTCTFCKKEIWNTKDSVVVQTGSGSSFQE----------FCTSVCLSLYEAQQQR--------------------------------PIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRA---------------------------------------------NKGLKTNCCDQCGAYIYARPGGLGPELLFHDGQQKRFCNTTCLGAYK------------------------------------------KKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQ----HTSPEG-------------------------------------------------------------GIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGV----VSQCEHCR-QEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLG-LCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNL----------------------------DTQSGPESLLNSQSSESKPQTPSQTKVENNNTVRTPEENENLGKIPVK-RVISSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTE--E-WKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDL----------------VSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLMLSESCSRDSLSSQPSCTG----------------------LNYSYGVNAWKCWVQSKYANGETSKGDELRFG-------------------------------PKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFS-RVEEEHLWECKQLGVYSPFVLLN----TLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYY---------------------------APVRQRKGRDTGPGKRKREDET-ILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS--MLESMLNRILAVREIYEELGRPGEEDLD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLM4-1", "uniprot_id": "ZMYM3_MOUSE", "id": "Q9JLM4-1", "name": "Zinc finger MYM-type protein 3", "aln": "-------------------------------------------------------------------------MDPSDFP----SPFDPLTLPEKPLAGDLP-VDMEFG--EDLLESQTAPSRG-----------WAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGATELLGLGG---LLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMP---PDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEE-IPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGET-LGDGINSSQS-KPGVCTPTAHPSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSD--------EDSDAMVDDPNDEDFVPFRPRRSPRMS----LRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTYSKK------PLGRKTCTFCKKEIWNTKDSVVVQTGPGGSFHE----------FCTSVCLSLYEAQQQR--------------------------------PIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRA---------------------------------------------NKGLKTNCCDQCGAYIYARPGGLGPELLFHDGQQKRFCNTTCLGAYK------------------------------------------KKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQ----HTSPEG-------------------------------------------------------------GIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGV----VSQCEHCR-QEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLG-LCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNL----------------------------DTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTPDENGNLGKTPVK-RATPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKAEMKSKGSQTE--E-WKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDL----------------VSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLMLSESCSRDSLSSQPSCTG----------------------LNYSYGVNAWKCWVQSKYANGETSKGDELRFG-------------------------------PKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFS-RVEEEHLWECKQLGVYSPFVLLN----TLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYY---------------------------APVRQRKGRDTGPGKRKREDET-ILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS--MLESMLNRILAVREIYEELGRPGEEDLD---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14202-1", "uniprot_id": "ZMYM3_HUMAN", "id": "Q14202-1", "name": "Zinc finger MYM-type protein 3", "aln": "-------------------------------------------------------------------------MDPSDFP----SPFDPLTLPEKPLAGDLP-VDMEFG--EDLLESQTAPTRG-----------WAPPGPSPSSGALDLLDTPAGLEKDPG-VLDGATELLGLGG---LLYKAPSPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVP---PDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGET-LGDGINSSQT-KPGGSSPPAHPSLPGDGLTAKASEKPPE--RKRSERVRRAEPPKPEVVDSTESIPVSD--------EDSDAMVDDPNDEDFVPFRPRRSPRMS----LRSSVSQRAGRSAVGTKMTCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKK------PSGKKTCTFCKKEIWNTKDSVVAQTGSGGSFHE----------FCTSVCLSLYEAQQQR--------------------------------PIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRA---------------------------------------------NKGLKTNCCDQCGAYIYTKTGSPGPELLFHEGQQKRFCNTTCLGAYK------------------------------------------KKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQ----RTSPEG-------------------------------------------------------------GIHLSCHYCHSLFSGKPEVLDWQDQVFQFCCRDCCEDFKRLRGV----VSQCEHCR-QEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLG-LCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKSKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNL----------------------------DTQSGPESLLNSQSPESKPQTPSQTKVENSNTVRTPEENGNLGKIPVKTRSAPTAPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTE--E-WKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTDKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDL----------------VSNQSAEGLLEDCDLFGPARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRTMRKGQKRLVLSESCSRDSMSSQPSCTG----------------------LNYSYGVNAWKCWVQSKYANGETSKGDELRFG-------------------------------PKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFS-RVEEEHLWECKQLGVYSPFVLLN----TLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYY---------------------------APVRQRKGRDTGPGKRKREDEAPILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS--MLESMLNRILAVREIYEELGRPGEEDLD---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2TAL8-1", "uniprot_id": "QRIC1_HUMAN", "id": "Q2TAL8-1", "name": "Transcriptional regulator QRICH1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQG-------GNCIYTDSTEVAGSLLELACPVTTS--------------VQPQTQQEQQIQVQQPQQVQVQVQVQQS------------------PQQVSAQ-LSPQLTVHQP----TEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAA------EIPEEHIPHQQIQAQLVAG----QSLAGGQQIQ----------IQTVGALSPPPSQQG------------------------------------------SPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPV---------------------------------------------ATVLAIPQGQQQ-SYVSLR-----PDLLTVDS-----------------------------------------------------------------------------------------------------------------------------------AHLYSATGT-----------ITSPTG------------------------------------------------------------------ETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGS----PTALAAVK-LEDDKEKMVGTTSVVKNSHEEVVQTLANSLFPAQF-----------------------------------------------------MNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQ----------------------------QTPQ------------------------------------------------------EQTPPPQQQQQQLQVTCSAQTVQVAEVE---------------------------------------------PQSQPQPSPE-LLLPNSLKPEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLEVWKNWAQTKNAELEKDAQNRLAPIGR-----------------------------RQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLT----TLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLK---------------------------ALGIHQTG--------QKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISRE--QMGQMLTRILVIREIQEAIAVANASTMH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UA37-1", "uniprot_id": "QRIC1_MOUSE", "id": "Q3UA37-1", "name": "Transcriptional regulator QRICH1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQG-------GNCIYTDSTEVAGSLLELACPVTTS--------------VQPQTQQEQQIQVQQPQQVQVQVQVQQS------------------PQQVSAQQLSPQFTVHQP----AEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAA------EIPEEHIPHQQIQAQLVAG----QSLAGGQQIQ----------IQTVGALSPPPSQQG------------------------------------------SPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPV---------------------------------------------ATVLAIPQGQQQ-SYVSLR-----PDLLTVDS-----------------------------------------------------------------------------------------------------------------------------------AHLYSATGT-----------ITSPTG------------------------------------------------------------------ETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGS----PKALAAVK-LEDDKEKMVGTTSVVKNSHEEVVQTLANSLFPAQF-----------------------------------------------------MNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQ----------------------------QTAQ------------------------------------------------------EQTPPPQQQQQQLQVTCSAQTVQVAEVE---------------------------------------------PQSQPQPSPE-LLLPNSLKPEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLEVWKNWAQTKNAELEKDAQNRLAPIGR-----------------------------RQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLT----TLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKSPSNPKDKSTSIRYLK---------------------------ALGIHQTG--------QKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISRE--QMGQMLTRILVIREIQEAIAVANATTMH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95789-3", "uniprot_id": "ZMYM6_HUMAN", "id": "O95789-3", "name": "Zinc finger MYM-type protein 6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEPLDGECGKAVVPQQELLDKIKEEPDNAQEYGCVQQPKTQESKLKIG--------------GVSSVNERPIAQQLNPGFQLSFA----SSGPSVLLPSVPAVAIKVFCSGCKKMLYKGQTAYHKTGSTQLFCSTRCITRHSSPACLPPPP--KKTCTNCSKDILNPKDVITTRFENSYPSKD----------FCSQSCLSSYELKKKP--------------------------------VVTIYTKSISTKCSMCQKN-ADTRFEVKYQNVVHGLCSDACFSKFHS---------------------------------------------TNNLTMNCCENCGSYCYSS--SGPC-------QSQKVFSSTSVTAYK------------------------------------------QNSAQIPPYALGKSLRPSAEMIETTNDSGKTELFCSINCLSAYRVKTVTSSGVQVSCHSCKTSAIPQYHLAMSNGTIYSFCSSSCVVAFQNVFSKPKGTNSSAVPLSQGQVVVSPPSSRSAVSIGGGNTSAVSPSSIR-GSAAASLQPLAEQSQQVALTHTVVKLKCQHCNHLFATKPELLFYKGKMFLFCGKNCSDEYKKKNKV----VAMCDYCK-LQKIIKETVRFSGVDKPFCSEVCKFLSARDFGERWG-NYCKMCSYCSQTSPNLVENRLEGKLEEFCCEDCMSKFTVLFYQMAKCDGCKRQGKLSESIKWRGNIKHFCNLFCVLEFCHQQIMNDCLPQN---------KVNISKAKTAVTELPSARTDTTPVITSVMSLAKIPATLSTGNTNSVLKGAVTKEAAKIIQDESTQEDAMKFPSSQSSQPSRLLKNKGISCKPVTQTKATSCKPHTQHKECQTDLPMPNEKNDAELDSPPSKKKRLGFFQTYDTEYLKVGFIICPGSKESSPRPQCVICGEILSSENMKPANLSHHLKTKHSELENKPVDFFEQ-KSLEMECQNSSLKKCLLVEKSLVK---ASYLIAFQTAASKKPFSIAEEL----IKP-YLVEMCSEVLGSSAGDKMKTIPLSNVTIQHRIDELSADIEDQLIQKVRESKWFALQIDESSEISNITLLLCYIRFIDYDCRDVKEELLFCIEMPTQITGFEIFELINKYIDSKSLNWKHCVGLCTDGAASMTGRY--SGLKAKIQEVAMN-TAAFTHCFIHRERLVAEKLSPCLHKILLQSAQILSFIKS---NALNSRMLTILCEEMGSEHVSLPLHAEVRWISR-GRMLKRLFELRHEIEIFLSQKHSDLA-KYFHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKRKLKMWLKRTQENDYDMFPSFSEFSNSSGLNMTDITRIIFEHLEGLSQVFSDCFPPEQDLRSGNLWIIHPFMNHQNNNLTDFEEEKLTELSSDLGLQALFKSVSVTQFWINAKTSYPELHERAMKFLLPFSTVYLCDAAFSALTESKQKNLLGSGPALRLAVTSLIPRIEKLVKEKE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4AEF5-1", "uniprot_id": "D4AEF5_RAT", "id": "D4AEF5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEPLDGGCDKAMA-QQGLLDRIKEEPDDAHEYG------PQESELKIS--------------AVFSASDT------SLGFQVGLP----SPGLSASFPAVP--AAQVFCFGCKQLLRKGQPTYRKAGSAQLFCSMGCVITFSSAVCVPPLP--KRTCAHCSKDILNPMDVITTQFENSSLCKE----------FCSQSCLFSYELKK-P--------------------------------VVTIYTSGISAKCSMCQKG-TD----------------------------------------------------------------------------------------------------------------------------------------------------------------NLAPKPLYALGNSSRLSAEMIETTNDSGRTELFCSINCLSAYRIKTVISSGIQVLCHSCKTAAVPQYHLAMSNGTICSFCSSNCVLAFQNVFNKPKGRNSSLAPISQGQEVLSAP-MQSAVSARKEAPAPSFSSPIS-NPAAAALETLAKESHQIALTLSFLKLTCLQCSLLFATKPELLFYKGRMFMFCGKACCDEYKRQNKV----KALCDYCK-LQKTIEDTVRFSGVDKPFCSEVCKVLSARDFGERWG-NYCKTCSYCLQTSANFVENQLEGKLQVFCCEDCMSKFTALLYQTARCDACKRQGKLSESLKWRGNIKYFCNLFCVLKFCHQYSANDPIPQRKVFVLPKPAQVIIPKVQTAMTALPSPKIATTPVITSVTSLAKIPALQPSRNTNSVCTDAGPTEATKIIGNGSKPAAAERLQSPQAP---KLLKNKGILCKPVTQTKATSCRPHTHHVACQTDSPLPDGKN-EEYDSPPAKRRRVDFFHTCNADYIKFGFIICSGSKESSPSPQCVICGEILPSESVMPVSLSNHLKAKHSDLENKPIDFFEE-KSLEMECQNSSLKKCLLVEESLVK---ASYLIAFQIAARNKPFSIAEEL----IKP-YLVEMCSEVLGSSAGDKMKTIPLSNSTIGCRIKKLSEDIEDQLLQKVRESRWFALQVDESSEVTDVPLLLCYVRFVDYDCGDVKEELLFCTEMPSPSTDLKVFELINQYIDSRSLHWNHCVGFCTDGAASLTDEC--SHLRSKIQEIAKN-TVTFTHCFIHREHLAAEKLSPCLHEILLQLSQILSFVKN---SASDSRMLTILCEEVGSGHVSLPLSAEVRWLAR-GRILTRLFELRHEIEIFLNQKHSDLA-RYFHDEEWVAKLAYLADIFSLINKLNSSLQGTMTTFFSLYNKVEIFKKRLKMWLKRAQENDYDMFPLFSEFLDSSDVSVRNIASIICEHLEGLSQVFHDCYPPEKDLRSGNLWLLNPFASYQDNNLTDSEEENLAALSSDTRFQSVHKSMSVTQFWVNAKTSYPELHEKAMKLLLPFSSTCLCDAAFSALTASKQRDLRTYSPSLRLAVTSLVPRIDKLAKEKD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5YBQ0-1", "uniprot_id": "A0A8I5YBQ0_RAT", "id": "A0A8I5YBQ0-1", "name": "", "aln": "---------------------------------------------------------MRGASGTQGVRLRFCILEFEQKSDAVFDEIVENCG-VMDTEMSEDTDHNLTPTLASMSYGMPSQTGSENSLLDEDDYFLNSGDLAGIPVVSSDNEDEQDFSSKDNLVSSAHTDGSLEIERRASHHESDNENEIQIQSQLKKDFPKQFDQVSVFKSIRKDFCLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKGLDSRLKSSFFDKAANQVEETLHTHLPQNPETNFRDSSYPFANKESIGSELGNSFASNIR---IKEEPLDDEYDKAVAPQQGLLDRVKDEPDNAQEYGHGQQQKTQEGELKIS--------------AVFSVSGSPLAPQLTTGFQPSLA----SPGMNKMLPAVPATAIRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPLTKKTCSSCSKDILNPKDVISAQFENSTTSKD----------FCSQSCLSTYELKKKP--------------------------------IVTINTNSISTKCSMCQKN-AVIRHEVNYQNVVHKLCSDACFSKFRS---------------------------------------------ANNLTMNCCENCGGYCYSG--SGQCHVLQIEGQSKKFCSSMCVTSYK------------------------------------------QKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVLAFQNLFNKPTGMNSSVVPLSQGQVIVSIP-TGSSASAGGGSTPAASPTSVHSSSAAAGLQRLAAQSQHVGFARSVVKLRCQHCNRLFATKPELLDYKGKMFQFCGKNCSDEYKKINNV----MAMCEYCK-IEKIIKETVRFSGADKSFCSEGCKLLYKHDLGKRWG-SHCKMCSYCLQTSPKLIQNNLGGKVEDFCCEECMSKYTVLFYQMAKCDGCKRQGKLSESLKWRGDIKHFCNLLCILMFCHQQTVCDPPLQNN--------TASISMVQAASAGPPSLRKDSTPVIANVVSLASAPAAQPTANANSVLQGAVPTVTAKIIGDASTQTDALKLPPSQPP---RLLKNKALLCKPITQTKATSCKPHTQNKECQTE-DTPSEPQVMVVPVPVPVFVPIPLHLYTQYTPVPFGIPVPMPVPMFIPSSMNNEEKASEGIEDIKEKLATHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNAVQDADSELKQFSKGETEQDLEADFPSESFDPLNKGQGIQARSRTRRRHRDGFPQPRRRGRKKSVVPVEPRSL---------IQGALQGCSVSGMTLKYMYGVNAWKNWVQWKNAKDEQGDLKCGGGEHASASPC--SDSLGSAQDQALSQESSEQGCKVRSMKLKEDILSCTFSELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPY-SRFMIELTKLLKIWEPTILPNGYMFS-RIEEEHLWECKQLGAYSPIVLLN----TLLFFNTKYFQLKNVTEHLKLSFAHVMRRTRTLKYSTKMTYLRFFPPP------------------------PQKQESEPDKLTIGKRKRNEDEEAPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRTDVFYLQPERSCVPNSPMWYSTFPIDPG--TLDTMLTRILMVREVHEELAKAKSEDSDVELSD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A791-1", "uniprot_id": "ZMYM4_MOUSE", "id": "A2A791-1", "name": "Zinc finger MYM-type protein 4", "aln": "---------------------------------------------------------MAEREVETGPRKR-----FEQKSDAVFDEIVENCG-VMDTEMSEDTDHNLTPTLASMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVSSDNEDEQDCSSKDNLVSSVHTDGSLEVERRAAHQESDNENEIQIQNQLKKDFPKQFDQVSVFKSIRKDFCLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKGLDSRLKSSFFDKAANQVEETLHTHLPQNPETNFRDSSYPFASKESIGSELGNSFASNIR---IKEEPLDDEYDRAVAPQQGLLDRVKDEPDNAQEYSHGQQQKTQEGELKIS--------------AVFSVSGSPLAPQLTTGFQPSLA----SPGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPLTKKTCSSCSKDILNPKDVISAQFENSTTSKD----------FCSQSCLSTYELKKKP--------------------------------IVTINTNSISTKCSMCQKN-AVIRHEVNYQNVVHKLCSDACFSKFRS---------------------------------------------ANNLTMNCCENCGGYCYSG--SGQCHVLQIEGQSKKFCSSMCVTSYK------------------------------------------QKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPTGMNSSVVPLSQGQVIVSIP-TGSSASAGGGSTPAVSPTSIN-SSAAAGLQRLAAQSQHVGFARSVVKLRCQHCNRLFATKPELLDYKGKMFQFCGKNCCDEYKKINNV----MAMCEYCK-IEKIIKETVRFSGADKSFCSEGCKLLYKHDLGKRWG-SHCKMCSYCLQTSPKLIQNNLGGKVEDFCCEECMSKYTVLFYQMAKCDGCKRQGKLSESLKWRGDIKHFCNLLCILMFCHQQTVCDPPLQNNA-------VASISMVQAASAGPPSLRKDSTPVIANVVSLASAPAAQPTANTNSVLQGAVPTVTAKIIGDASTQTDALKLPPSQPP---RLLKNKALLCKPITQTKATSCKPHTQNKECQT--DTPSEPQVMVVPVPVPVFVPIPLHLYTQYTPVPFGIPVPMPVPMFIPSSMDNDEKATEGIEDIKEKLATHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNAVQDADSELKPFSKGETEQDLEADFPSESFDPLNKGQGIQARSRTRRRHRDGFPQPRRRGRKKSVVPVEPRSL---------IQGALQGCSVSGMTLKYMYGVNAWKNWVQWKNAKDEQGDLKCGGGELASASPC--SDSLGSAQDHALSQESSEQGCKARSVKLKEDILSCTFSELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPY-SRFMIELTKLLKIWEPTILPNGYMFS-RIEEEHLWECKQLGAYSPIVLLN----TLLFFNTKYFQLRNVTEHLKLSFAHVMRRTRTLKYSTKMTYLRFFPP-------------------------LQKPESEPDKVTIGKRKRNEDDEAPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRSDVFYLQPERSCVPNSPMWYSTFPIDPG--TLDTMLTRILMVREVHEELAKAKSEDSDAELSD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZL5-1", "uniprot_id": "ZMYM4_HUMAN", "id": "Q5VZL5-1", "name": "Zinc finger MYM-type protein 4", "aln": "---------------------------------------------------------MAEREVESGPRKR-----FEQKSGAVFDEIVENCGGIMDTEMSEDIDHNLTPTLDSMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVGSDNEDEQDFSSKDNLVSSIHTDDSLEVERRVTQHESDNENEIQIQNKLKKDFPKQFDQVSVFKSIRKDFSLVRENSKETFSGKEKNRDLTYE-REKRLDKPHKDLDSRLKSSFFDKAANQVEETLHTHLPQTPETNFRDSSYPFANKESIGSELGNSFASNIR---IKEEPLDDEYDKAMAPQQGLLDKIKDEPDNAQEYSHGQQQKTQEGELKIS--------------AVFSVSGSPLAPQLTTGFQPSLA----SSGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPLTKKTCSSCSKDILNPKDVISAQFENTTTSKD----------FCSQSCLSTYELKKKP--------------------------------IVTINTNSISTKCSMCQKN-AVIRHEVNYQNVVHKLCSDACFSKFRS---------------------------------------------ANNLTMNCCENCGGYCYSG--SGQCHMLQIEGQSKKFCSSSCITAYK------------------------------------------QKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPTGMNSSVVPLSQGQVIVSIP-TGSTVSAGGGSTSAVSPTSIS-SSAAAGLQRLAAQSQHVGFARSVVKLKCQHCNRLFATKPELLDYKGKMFQFCGKNCSDEYKKINNV----MAMCEYCK-IEKIVKETVRFSGADKSFCSEGCKLLYKHDLAKRWG-NHCKMCSYCLQTSPKLVQNNLGGKVEEFCCEECMSKYTVLFYQMAKCDACKRQGKLSESLKWRGEMKHFCNLLCILMFCNQQSVCDPPSQNN--------AANISMVQAASAGPPSLRKDSTPVIANVVSLASAPAAQPTVNSNSVLQGAVPTVTAKIIGDASTQTDALKLPPSQPP---RLLKNKALLCKPITQTKATSCKPHTQNKECQTE-DTPSQPQIIVVPVPVPVFVPIPLHLYTQYAPVPFGIPVPMPVPMLIPSSMDSEDKVTESIEDIKEKLPTHPFEADLLEMAEMIAEDEEK-KTLSQGESQTSEHELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNAVQEADSELKQFSKGETEQDLEADFPSDSFDPLNKGQGIQARSRTRRRHRDGFPQPRRRGRKKSIVAVEPRSL---------IQGAFQGCSVSGMTLKYMYGVNAWKNWVQWKNAKEEQGDLKCGGVEQASSSPR--SDPLGSTQDHALSQESSEPGCRVRSIKLKEDILSCTFAELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPY-SRFMIELTKLLKIWEPTILPNGYMFS-RIEEEHLWECKQLGAYSPIVLLN----TLLFFNTKYFQLKNVTEHLKLSFAHVMRRTRTLKYSTKMTYLRFFPP-------------------------LQKQESEPDKLTVGKRKRNEDDEVPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRNDVFYLQPERSCVPNSPMWYSTFPIDPG--TLDTMLTRILMVREVHEELAKAKSEDSDVELSD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6F4-1", "uniprot_id": "A0A8M2B6F4_DANRE", "id": "A0A8M2B6F4-1", "name": "", "aln": "MVRSCVYPGCFNLNKVVRLRASSSTGDEKLTFHRFPLNDPERLTQWLLAIRWDVNTPWKKIDGSRLCSEHFTPEDYKPDEGQIRRLLKSSAVPVPVQGFEPNEVCIELDANEETEIDPESQSIDDSFDFEDEEAYFDDDDDIQSTVGRQKNPRSCPGERLQSRLILTVTNPSTEPTTPPSVFGTYYALSPTWYYQMDDPSKIGLHMEEPFNENVNMDFVANKEAGGFLNHELSKGHSHVCRRSRPEKRNPLSQDRGSKRSAPGSPEDATDSDNEDKDINTEENAQCSEELVITKVEDLSNETEFDQNENYSGKMDMDEPEDSEALRAKGLKSRPAHSSAVTQTQAADKRFAGFDPSDVLPVKIKDEPMDEEWKKAPQSPLRSIKDDEDFDQQRLGSYHQVPGVNNASTGAQTESIQNFKRLGVLCTACNKVLLKGQTAFQRSGSAKIYCSLECLRSTKN-----------KACHHCLKEIHEDSSIIVAPVDMSGAGKE----------FCSQKCR-----------------------------------------------NALTFKCSVCQKAGIRHVHEVNFRGSIQKLCSDGCFNQFRS---------------------------------------------SNKLNMNSCVNCGGFCYGT--DAQCPSLRMEDRVMKFCSQTCLTAYK------------------------------------------KRSLKLVTCKTCHALRPAEDALDSPNAEGIRELFCSVSCVTASKDQTVGLSAAPVECNNCKLKLVPQYHIAMSEGSVQNFCTFSCVVAYQESLNNKKANTQVNTVTSTSSNTTTAAKTAAPKPASSESSSAAKTSTPS------------------GQGQNVTKIPCCQCLNAFFHKPELMEYKRKMYAFCGNDCIDEFRKVNRV----VARCENCN-LNKRVKVVRRINRVDRSFCEEKCRALFEQNLVKRWGTKHCSNCFHCNSTSKTVVTEVFNGKQEEFCGSDCLSQHNLLIRQEIKCSMCRQIKKMNESVKWLGEMKHFCSLRCLMFFCSLQGITGAVIKATS------KSLATQCAKPMSSAVTQKPKEATPVIASVVSLSGPSSKQPGVSGNTNAKGSVQTDVTMKHKRN--------------------LRSQILQNKSPSKNKSTTCKPHTADAEIQKD----EAPKVIVLPVPVPVYVPVPMNLYSQYVPKSVGMPLPVPVPLFFPTTLDSAEHIVQTIQEIKEKIPDDPLEADLIMMAEMVAEDAEKEKHISSCDQTDNIMEDLDLQDLSSN-------LSWEEDPVSPAQILDQTPEPEPPPPPPPPAPASTPTPTFAPASTPTFAPASTPTPTFAPVSTPTFAPAPSSRSATMTLVSTKAGEPLMDLEADFP--------------IETIALLREQMENDSGKRRSCKKGPDVSTQKKRGRKCASVPSNILSKLQHEYGVKAWRDWVRWKNAQPNSDAPKFGSRSMTLKEDVLKCCTAELSYGLCKFITEVRRPNGEKYSPDSIYYLCLGIQQYLFENNRMENIFSDVFYTKFCWEMSNILKGWKPTILPNGYIHS-RVEEEFLWNCKQLGAFSPGVLLN----TLIYFFTKYFNYRTVEQHRLLSFAHVKRYTRGPANAKVSFLR------------------------------FYPPKEDSSDDGVPAKKRKKDDERQRVLKIGQNSDNPLHCPVRLYEFYLSKCSPGIRHHATKFYLSPERSCVPSSPTWFSISALSDE--ALDSMLSRILTVRELHMETEQTPADTDSDSDSDYNQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JRE3-1", "uniprot_id": "A8JRE3_DROME", "id": "A8JRE3-1", "name": "", "aln": "-------------------MEEISSLDSFGADSNARPESATPRSEEQQDQDRQQTAPAASETLDTPASPPAEDAAAQESKPPPSKEADDDFEQISEGSLDADDNQSRDKAASTPADPVDAEEPAEEPTPNEEPQGGEDEQPQTEAVRVDPQEEPEEAEEETDALQATAEEVEAAAAEADAVDGGPASPEAMDVDEGEVDAEGEAEQEAEDDAALDREATDDVDMQSVGADSHQAEDAEPPEGRDEVDTSLEEQENGQDPDEREKDAAADEDDPDAEGDAESEQVDENAEETGEAEHGDDTVENVLEPEESDVCLIPDDQETEVTEAEKELARENAEKAAEEEEAEERQAKTPDNDRKSPADAAADPEDDSAAAVDATDVSPTTPTDAQAGAKSAATGIAEADGVAAAANEEEAGGDVPDPDEPTAEESSSAGAGEPGSTPKIIISWIVGSVQKCKQCGDEKNCGFRYRSPEESEEMDKEKENDKAEENAEEGEEEEARQKPAAPSGFEYICDTACVDALLEDQPGKYFVRRKKFLVEEVVREEGAAEAEASADGEGGDAEEEATPANTQDCLQCKDKTRCKYFIKQDQDCFYICNDDCFNLLNAEEPDKFKLKRHSIRVRNIGATTLQPPQNSPTKRTDGSVVARTVEEAETARLDRIESFRRRCADCEADINTDEKQLMWETMDFCNEVCLGSYQRTIGSTCETCKQEVSSIALGKYCVRFGFDVRQFCCAGCLNTFKKGLKTCSCCQKDISGGQEGFLAPVGDKDQFKDFCSQSCLRRYESMCNPRRKLRTDVCGVCNNQKPVRVEMLLEDREHYFCSNPCFSAFKFVSNVNADPCAMCSKYFERRSAESYTIYNEQQSPKVFCSRVCINVYIIVN------------------RHIVSCQWCKVKKYNFDMIYQIGGPHDQETLTCSINCLTMHGVSCNISARAVTKCDNCSNFNTPQYHLTMSDASMRNFCTYQCVMQFQNQFARAPLTLDSDLPPSSAGSSKSQQQSNRGNKNAAPFPTGLPKRVKLKLSHTGKGGVGGKKSGSGTMLPVISTVQSLASGETEARIGNLTVRRKRGRPRES------------GTSSPPLSMPGVHPPAQRGRPRKHAVDYSARSPSPTMSGGSSHMGIPVRRNTTTTMDFGPATVTETKIITVPPYPKAVRNVNISCKPLTVTQGEQCSPDVRDCATQTEK---DYSNKVLIPVPVPIFVPQPMYMYSAPFPVPVPIPLPIPVPIFIPTTRNTAQGILKEIKKIQDKMPEDPLEAELLMMAEMVAEEKHESDSDSDNEIKPDPGLVALQYQNSLESVAQQQQQQQVVDVSGAGHNPYGDDMLQIALKMATGDYDNHHQTSTVDLETSMTANTISSQSPMGHDGMGQMGVHHLDQQHHMLDATQRTARGRKRGVGVVMDPPNRN-----------------SRSPVKRQRGGEMDHSALQQQSQQAQQPQEKPDAQMFLKYTFG-----VNAWKQWVMTKNADIEKSSMRRRPFKTELLQMTADELNYSLCLFVKEVRKPNGTEYAPDTIYYLVLGIQQYLYVNGRIDNIFYDPYYERFTECLDEVARKFSVLYNDSQYIVT-RVEEEHLWECKQLGAHSPHVLLS----TLMFFNTKHFNLTTVEEHMQLSFSHIMKHWKRSSQNSKVPGSRNVLLR----------------------------------FYPPQAGLDANPRKKKVYEQQENEENPLRCPVRLYEFYLSKCPESVKTRNDVFYLQPERSCVPDSPVWYSTQALGQD--ALQRMLHRVKMVKEINIALLTT---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : : . : . . . : : : : . . : :. .. . * . . : : : : : :: . : . : : : . :: : : : . . : .: * * . *:. :* *..* . : : : : . :: . : . . . . * . : : . : : ", "identical_positions": 8, "similar_positions": 76, "identity": "0.44%" }, { "cls_id": "homologset.agr.FB:FBgn0010329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05754-1", "uniprot_id": "DOPO_RAT", "id": "Q05754-1", "name": "Dopamine beta-hydroxylase", "aln": "-------------------------------------------MQPHLSHQPCWS-LPSPSVREAASMYGTAVAIFLVILVAALQGSEPPESPFPYHIPLDPEGTLELSWNVSYDQEIIHFQLQVQGPRAG--VLFGMSDRGEMENADLVMLWTDGDRTYFADAWSDQKGQIHLDTHQDYQLLQAQRVSNSLSLLFKRPFVTCDPKDYVIEDDTVHLVYG-----ILEEPFQSLEAINTSGLHTGLQQVQLLKPEVSTPAMPADVQTMDIRAPDVLIPSTETTYWCYITELPLHFPR-HHIIMYEAIVTEGNEALVHHMEVFQCTN-ESEAFPMFNGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGVPLGSSGSSRFLRLEVHYHNPRNIQGRRDSSGIRLHYTASLRPNEAGIMELGLVYTPLMAIPPQETTFVLTGYCTDRCTQMALPKSGIRIFASQLHTHLTGRKVITVLARDGQQREVVNRDNHYSPHFQEIRMLKNAVTVHQGDVLITSCTYNTENRTMATVGGFGILEEMCVNYVHYYPKTELELCKSAVDDGFLQKYFHIVNRFGNEEVCTCPQASVPQQFASVPWNSFNRDMLKALYNYAPISVHCNKTSAVRFPGNWNLQPLPNITSAVEEPDPRCPIRQTRGPAGPFVVITHGGRH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64237-1", "uniprot_id": "DOPO_MOUSE", "id": "Q64237-1", "name": "Dopamine beta-hydroxylase", "aln": "-------------------------------------------MQAHLSHQPCWSSLPSPSVREAASMYGTAVAIFLVILVAALRGSEPPESPFPYHIPLDPEGILELSWNVSYVQEIIHFQLQVQGLRAG--VLFGMSDRGEMENADLIMLWTDGDRAYFADAWSDRKGQIHLDSQQDYQLLQAQRTRDGLSLLFKRPFVTCDPKDYVIEDDTVHLVYG-----ILEEPFQSLEAINTSGLHTGLQRVQLLKSEVPTPSMPEDVQTMDIRAPDILIPDNETTYWCYITELPPRFPR-HHIIMYEAIVTEGNEALVHHMEVFQCAA-ESEDFPQFNGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPKEAGVPFGGPGSSPFLRLEVHYHNPRKIQGRQDSSGIRLHYTATLRRYDAGIMELGLVYTPLMAIPPQETAFVLTGYCTDKCTQMALQDSGIHIFASQLHTHLTGRKVVTVLARDGQERKVVNRDNHYSPHFQEIRMLKKVVTVYPGDVLITSCTYNTENKTLATVGGFGILEEMCVNYVHYYPQTELELCKSAVDDGFLQKYFHMVNRFSSEEVCTCPQASVPQQFSSVPWNSFNRDMLKALYDYAPISMHCNKTSAVRFPGEWNLQPLPKITSTLEEPTPRCPIRQTQSPANPTVPITTEADAE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09172-1", "uniprot_id": "DOPO_HUMAN", "id": "P09172-1", "name": "Dopamine beta-hydroxylase", "aln": "--------------------------------------------MPALSR---WASLPGPSMREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGSLELSWNVSYTQEAIHFQLLVRRLKAG--VLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQKGQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYG-----ILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSR-HHIIKYEPIVTKGNEALVHHMEVFQCAP-EMDSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQGRSPAGPTVVSIGGGKG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86B61-1", "uniprot_id": "TBH1_DROME", "id": "Q86B61-1", "name": "Tyramine beta-hydroxylase", "aln": "MLKIPLQLSSQDGIWPARFARRLHHHHQLAYHHHKQEQQQQQQQQQQQQAKQKQKQNGVQQGRSPTFMPVMLLLLMATLLTRPLSAFSNRLSDTKLHEIYLDDKEIKLSWMVDWYKQEVLFHLQNAFNEQHRWFYLGFSKRGGLADADICFFEN--QNGFFNAVTDTYTSPDGQWVRRDYQQDCEVFKMDEFTLAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPNVTAPHEAGVKMLQLLRADK-ILIPETELDHMEITLQEAPIPSQETTYWCHVQRLEGNLRRRHHIVQFEPLIR--TPGIVHHMEVFHCEAGEHEEIPLYNG--DCEQLPPRAKICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFNPYVRLEVHFNNPEKQSGLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYCVADCTRAALPATGIIIFGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHYKPRVLPGDALVTTCYYNTKDDKTAALGGFSISDEMCVNYIHYYPATKLEVCKSSVSEETLENYFIYMKRTEHQHGVHLNGARS-SNYRSIEWTQPRIDQLYTMYMQEPLSMQCNRSDGTRFEGRSSWEGVAATPVQIRIPIHRKLCPN-YNPLWLKPLEKGDCDLLGECIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *..: * : :: .:*. .* . * * : ::*** *.: :: : *:* . . :*:*.** : :**: .: . : :* . . .. ::*** : ::* *:* * **** * :.:.*:::*:. : * .: . : . *:: :***:.: : *:: : **. ******:: .* : * ***: :*.:: . .:*******:* * : .* :.* *.: * * : * :*:. **:** :* ** ***:.:*..* . ::*****::** .* *.**:*: : .** :*.:***** ** ***** :*:* *:***. **: ** :** **.******* * :*:* *. :: . **:*::** ****:* *: * **.*:*:* ***:: *::***.* :******:**** *:**:***:*. *::** ::* :. * .:: *: *.. . * * ::* *:*::**::...** *. . : :. :. * : : .* ", "identical_positions": 194, "similar_positions": 180, "identity": "28.57%" }, { "cls_id": "homologset.agr.FB:FBgn0010333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60763-1", "uniprot_id": "RAC3_HUMAN", "id": "P60763-1", "name": "Ras-related C3 botulinum toxin substrate 3", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60764-1", "uniprot_id": "RAC3_MOUSE", "id": "P60764-1", "name": "Ras-related C3 botulinum toxin substrate 3", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63000-1", "uniprot_id": "RAC1_HUMAN", "id": "P63000-1", "name": "Ras-related C3 botulinum toxin substrate 1", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63001-1", "uniprot_id": "RAC1_MOUSE", "id": "P63001-1", "name": "Ras-related C3 botulinum toxin substrate 1", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6RUV5-1", "uniprot_id": "RAC1_RAT", "id": "Q6RUV5-1", "name": "Ras-related C3 botulinum toxin substrate 1", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40792-1", "uniprot_id": "RAC1_DROME", "id": "P40792-1", "name": "Ras-related protein Rac1", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F7EM94-1", "uniprot_id": "F7EM94_RAT", "id": "F7EM94-1", "name": "small monomeric GTPase", "aln": "MKCRPSSVWWWVMGTTVTLVSPASCLLSFRAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05144-1", "uniprot_id": "RAC2_MOUSE", "id": "Q05144-1", "name": "Ras-related C3 botulinum toxin substrate 2", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15153-1", "uniprot_id": "RAC2_HUMAN", "id": "P15153-1", "name": "Ras-related C3 botulinum toxin substrate 2", "aln": "-----------MQAIKCVVVGDG-------AVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .:*. . ***********************************.**:**********************************.***:*******:******** ***:************:***:*::***:*********:*::*.:***********:***********:**** : : * ::", "identical_positions": 150, "similar_positions": 29, "identity": "71.43%" }, { "cls_id": "homologset.agr.FB:FBgn0010339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32233-1", "uniprot_id": "DRG1_MOUSE", "id": "P32233-1", "name": "Developmentally-regulated GTP-binding protein 1", "aln": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGG-GGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGN-RVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y295-1", "uniprot_id": "DRG1_HUMAN", "id": "Q9Y295-1", "name": "Developmentally-regulated GTP-binding protein 1", "aln": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGG-GGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGN-RVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32234-1", "uniprot_id": "128UP_DROME", "id": "P32234-1", "name": "Guanylate binding protein 128up", "aln": "MSTILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGG-GGTGEAGFEVAKTGDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLIFMVLDCLKPLGHKKLLEHELEGFGIRLNKKPPNIYYKRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGN-RIYIPCIYLLNKIDQISIEELDVIYKIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYTKPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVLNDEDVVQIVKKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39729-1", "uniprot_id": "RBG1_YEAST", "id": "P39729-1", "name": "Ribosome-interacting GTPase 1", "aln": "MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQIIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKIDSLSIEELELLYRIPNAVPISSGQDWNLDELLQVMWDRLNLVRIYTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSHILEDEDVVTILKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ** ** ***********: *** ***:********::. ..* ** **:**:** * :***************:*:*. **.* ******.**** *:*******:*******:*****:***:***********::::** *** **:::*:****.*****..**:* *:*:****.:. * :.*. : ::::::**:*:.*::::* *** ******:*.. * *:*.**:*****.:*****:::*::*:.****: : **:*:**: :*: *.* *********:**:..**** .* :::*** ::*:.: .:*: ***:* ****:** ** .* *:****: *:** ", "identical_positions": 219, "similar_positions": 100, "identity": "59.19%" }, { "cls_id": "homologset.agr.FB:FBgn0010340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY94-1", "uniprot_id": "TIDC1_RAT", "id": "Q6AY94-1", "name": "Complex I assembly factor TIMMDC1, mitochondrial", "aln": "MEAPPPAPRSRLCG---------AWGPFPRVFAAGAVAADSQSFVEDPELRSYVSDPGSSESGWDRLRQLFVKDEQRKISKEMDYICRAALSAGIIGWAYGGIPAFIYAKRRYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWSWRTAVFVTIFNTVNTGLTVYRNKDALSHFAIAGAVTGGLFRINLGLRGLVAGGIIGALLGTPMGSLLMALEKHCGETVQERRQKDREAQQEQRLEEWRRNLQVTELLPMEIESGLEKIQPEKDAQRIEELLRLPRNPASPDKQSED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUY5-1", "uniprot_id": "TIDC1_MOUSE", "id": "Q8BUY5-1", "name": "Complex I assembly factor TIMMDC1, mitochondrial", "aln": "MGAPPPAPRSRLCG---------AWGPFPRVFAAGAVAADSPGFVEDREQRSGVSDPGSLESGWDRLRQLFAKDEQQRFSKEIDYIYRAAVSAGIIGWAYGGIPAFIYAKKRYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWSWRTAVFVTIFNTVNTGLTVYRNKDAMSHFAIAGAVTGGLFRINLGVRGLVAGSIIGALLGAPMGSLLMALEKYSGETVQERRQKEWKALHEQRLEEWRSSLQVTELLPMEIESGLEKIQPEGDAQRIEELLSLPRNPSSPHQQSKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPL8-1", "uniprot_id": "TIDC1_HUMAN", "id": "Q9NPL8-1", "name": "Complex I assembly factor TIMMDC1, mitochondrial", "aln": "MEVPPPAPRSFLCR---------ALCLFPRVFAAEAVTADSEVLEERQKRLPYVPEPYYPESGWDRLRELFGKDEQQRISKDLANICKTAATAGIIGWVYGGIPAFIHAKQQYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWGWRTAVFVTIFNTVNTSLNVYRNKDALSHFVIAGAVTGSLFRINVGLRGLVAGGIIGALLGTPVGGLLMAFQKYSGETVQERKQKDRKALHELKLEEWKGRLQVTEHLPEKIESSLQEDEPENDAKKIEALLNLPRNPSVIDKQDKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568N3-1", "uniprot_id": "TIDC1_DANRE", "id": "Q568N3-1", "name": "Complex I assembly factor TIMMDC1, mitochondrial", "aln": "MCTAVRQDLSLKCGGTDVKQPGDSQPGHLRALLGFTLPSVYASDSSTQILPKHIGKPEFPDTGWDRIKDLFYNVEG-QYTEELRNVVKSGIASAIVGMIYGGLPGARHARQRFIQCSQAEIYRNRVDAVRAAHNAAIRGFLRFGWRWSWRVAAFVTLFNTVNTGLTVYRDQNALSHFAVSGAVTGGVFRLNLGLRGLLSGTIIGVILGFPAGVLILGLQNLGGETMRDKRRRERRELHELRVTEWNARLKVTDDLIGEMSS-LKHQDSEIDLQQVEELLSQPRNGNAAKGPYNQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P81928-1", "uniprot_id": "TIDC1_DROME", "id": "P81928-1", "name": "Complex I assembly factor TIMMDC1, mitochondrial", "aln": "MNFLWKGRRFLIAG----------------ILPTFEGAADEIVDKENKTYKAFLASKPPEETGLERLKQMFTIDEFGSISSELNSVYQAGFLGFLIGAIYGGVTQSRVAYMNFMENNQATAFKSHFDAKKKLQDQFTVNFAKGGFKWGWRVGLFTTSYFGIITCMSVYRGKSSIYEYLAAGSITGSLYKVSLGLRGMAAGGIIGGFLGGVAGVTSLLLMKASGTSMEEVR-----------YWQYKWRLDRDENIQQAFKKLTEDENPELFKAHDEKTSEHVSLDTIK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .: . : . ::* :*::::* * :.:: : ::. . ::* ***:. * .::: .** ::.:.** : : .* : *::*.**.. *.* : : * :.***.:.:: .: :*::**.::::.:*:**: :* *** :** * : : : * ::.: : ::. *. : : :.. :. :.* : * ", "identical_positions": 42, "similar_positions": 94, "identity": "14.29%" }, { "cls_id": "homologset.agr.FB:FBgn0010341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60953-2", "uniprot_id": "CDC42_HUMAN", "id": "P60953-2", "name": "Cell division control protein 42 homolog", "aln": "MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFN2-1", "uniprot_id": "CDC42_RAT", "id": "Q8CFN2-1", "name": "Cell division control protein 42 homolog", "aln": "MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60766-2", "uniprot_id": "CDC42_MOUSE", "id": "P60766-2", "name": "Cell division control protein 42 homolog", "aln": "MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40793-1", "uniprot_id": "CDC42_DROME", "id": "P40793-1", "name": "Cdc42 homolog", "aln": "MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCKFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19073-1", "uniprot_id": "CDC42_YEAST", "id": "P19073-1", "name": "Cell division control protein 42", "aln": "MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIKKSKKCAIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**********************:**::****************.*************************.**********:**.*********.**: *** .* *:*********: :*** ::: :*** * ..:**::**************:**********:****** .*.::* :*", "identical_positions": 147, "similar_positions": 30, "identity": "76.96%" }, { "cls_id": "homologset.agr.FB:FBgn0010348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BSL7-1", "uniprot_id": "ARF2_MOUSE", "id": "Q8BSL7-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84082-1", "uniprot_id": "ARF2_RAT", "id": "P84082-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84077-1", "uniprot_id": "ARF1_HUMAN", "id": "P84077-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84079-1", "uniprot_id": "ARF1_RAT", "id": "P84079-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84078-1", "uniprot_id": "ARF1_MOUSE", "id": "P84078-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61205-1", "uniprot_id": "ARF3_MOUSE", "id": "P61205-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61204-1", "uniprot_id": "ARF3_HUMAN", "id": "P61204-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61206-1", "uniprot_id": "ARF3_RAT", "id": "P61206-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61209-1", "uniprot_id": "ARF1_DROME", "id": "P61209-1", "name": "ADP-ribosylation factor 1", "aln": "MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11076-1", "uniprot_id": "ARF1_YEAST", "id": "P11076-1", "name": "ADP-ribosylation factor 1", "aln": "MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19146-1", "uniprot_id": "ARF2_YEAST", "id": "P19146-1", "name": "ADP-ribosylation factor 2", "aln": "MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGEAREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCATSGEGLYEGLEWLSNNLKNQS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*:..*:*:***********.*****:********::*************:***************:**.*****::**:*:***:*****.*:.**** : *** *****:*. *:*.******:**.*****:******:*:* *:**:******:******:**:*.*:* . ", "identical_positions": 132, "similar_positions": 39, "identity": "72.53%" }, { "cls_id": "homologset.agr.FB:FBgn0010350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35052-1", "uniprot_id": "CDS1_RAT", "id": "O35052-1", "name": "Phosphatidate cytidylyltransferase 1", "aln": "MLELRHRGGCPGPGGAGTPPPREGEAAGGDHETESTSDKETDIDDRYGDLDAR--GDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFQEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTWKV-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98191-1", "uniprot_id": "CDS1_MOUSE", "id": "P98191-1", "name": "Phosphatidate cytidylyltransferase 1", "aln": "MLELRHRGGCPGPGGAGAPPPREGEAAGGDHETESTSDKETDIDDRYGDLDAR--GDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTLKV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92903-1", "uniprot_id": "CDS1_HUMAN", "id": "Q92903-1", "name": "Phosphatidate cytidylyltransferase 1", "aln": "MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSR--TDSDIPEIPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7N6-1", "uniprot_id": "A0A8M1Q7N6_DANRE", "id": "A0A8M1Q7N6-1", "name": "Phosphatidate cytidylyltransferase", "aln": "MTELRRRG---GGDQDSAENISDKEADG--------DDRLAFPDEGDGEMVGD--SKAETPDAPPSTDNTPQCLNKALEGLSSRWKNWWIRGILSLTMIIGFFLIIYLGPIMLIIVVMGVQIKCFHEIITIGYRVYHSYELPWFRTLSWYFLICVNYFFYGETVADYFGALVQREEPLQFLVRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLIVVTQSHLVIQNLFEGMIWFIVPISIVICNDIMAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVLSFFFAYLLSQYQYFVCPVEYDSETNRFAVECEPSNLFMIQEYTLPAVVQNALRWKTVNLYPFQIHSIALSSFASLIGPFGGFFASGFKRAFKIKDFADTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLGIFNTLRNQLREKGLLPPAVEEAQ---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99L43-1", "uniprot_id": "CDS2_MOUSE", "id": "Q99L43-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRV-----VRED-APPEDKE-----------SESEAKLDG-ETASDSE--SRAETAPLPTSVDDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFALYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSAIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLKSHLTDKGILTSALEDE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XU8-1", "uniprot_id": "CDS2_RAT", "id": "Q91XU8-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRA-----VRED-APPEDKE-----------SESEAKLDG-ETASDSE--SRAETAPPPTSIDDTPEVLNRALSNLSSRWKNWWVRGILTMAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSLVGWKTMRMYPFQIHS-ALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLKSHLTDKGILMSALEEE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95674-1", "uniprot_id": "CDS2_HUMAN", "id": "O95674-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRV-----AHEPVAPPEDKE-----------SESEAKVDG-ETASDSE--SRAESAPLPVSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMIIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLIGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSVIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLRSHLIDKGMLTSTTEDE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56079-1", "uniprot_id": "CDS_DROME", "id": "P56079-1", "name": "Phosphatidate cytidylyltransferase, photoreceptor-specific", "aln": "MAEVRRRKGEDEPLEDTAISGSDAANKR-----NSAADSSDHVDSEEEKIPEEKFVDELAKNLPQGTDKTPEILDSALKDLPDRWKNWVIRGIFTWIMICGFALIIYGGPLALMITTLLVQVKCFQEIISIGYQVYRIHGLPWFRSLSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYIIGFVWFVLSLVKKYYIKQFSLFAWTHVSLLIVVTQSYLIIQNIFEGLIWFIVPVSMIVCNDVMAYVFGFFFGRTPLIKLSPKKTWEGFIGGGFATVLFGILFSYVLCNYQYFICPIQYSEEQGRMTMSCVPSYLFTPQEYSLKLFG---IG-KTLNLYPFIWHSISLSLFSSIIGPFGGFFASGFKRAFKIKDFGDMIPGHGGIMDRFDCQFLMATFVNVYISSFIRTP---SPAKLLTQIYNLKPDQQYQIYQSLKDNLGD--MLT----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38221-1", "uniprot_id": "CDS1_YEAST", "id": "P38221-1", "name": "Phosphatidate cytidylyltransferase", "aln": "MSDNPEMKP--------------------------HGTSKEIVESVTDATSKAIDKLQEELHKDASESVTPVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . : . . ** . : .* *: :* : : ** * : : * :: : *: *:* *:: : ** ::*.**:*: *:: *:.: .:* . . . *.:: *:*:.: **: ** ** ** * . ** : **: **:.* *::*:*:*:::*::**::* . :: **: **: *: **:* **::***** ***:*. * *.: .:: : ::. * : **:: * . :* * * : . : : : : *: *: *: *:*::.*********:**:**:***.. ******* **.***::*.:*.::* :** : : : *. .* : * * . :: ", "identical_positions": 120, "similar_positions": 122, "identity": "24.84%" }, { "cls_id": "homologset.agr.FB:FBgn0010352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI78-1", "uniprot_id": "ODO1_RAT", "id": "Q5XI78-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MFHLRTCAAKLRPLTASQTVKTFSQNKPAAI-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPT---TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMTCPSTGLEEDILTHIGNVASSVP--VENFTIHGGLSRILKTRRELVTN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPNLQEENFDISQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP--EDGPAAQNPDKVKRLLFCTGKVYYDLTRERKARDMAEEVAITRIEQLSPFPFDLLLKEAQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTIDRA-------------------------------------------------------------------------------------------------KPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60597-1", "uniprot_id": "ODO1_MOUSE", "id": "Q60597-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MFHLRTCAAKLRPLTASQTVKTFSQNKPAAI-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPT---TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMTCPSTGLEEDVLFHIGKVASSVP--VENFTIHGGLSRILKTRRELVTN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP--ENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTIDRA-------------------------------------------------------------------------------------------------KPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02218-1", "uniprot_id": "ODO1_HUMAN", "id": "Q02218-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MFHLRTCAAKLRPLTASQTVKTFSQNRPAAA-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPT---TTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMSCPSTGLTEDILTHIGNVASSVP--VENFTIHGGLSRILKTRGEMVKN-RTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIP--EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTISRA-------------------------------------------------------------------------------------------------KPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFKNFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JI08-1", "uniprot_id": "B8JI08_DANRE", "id": "B8JI08-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "----MHRLRTCAARLRPITASQTAKNLSQQGPAATPRTFQPLRCFSSPVAAEPFLNGTSSNYVEEMYYAWLENPKSVHKSWDIFFRNANAGAPPGTAYQSPPPLG-VSLAGLAQAQSLVGAQPNVEKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGIMDADLDSCVPTDIITSSDKLGFYGLEESDLDKVFRLPT---TTFIGGDESALPLREIIRRLEMAYCQHIGVEFMFINDLDQCQWIRQKFERPGVMQFSLEEKRTLLARMVRSTRFEEFLQRKWSSEKRFGLEGCESLIPALKTIIDKSSENGVDTVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDVKYHLGMYHRRINRVTNRNITLSLVANPSHLEAVNPVVQGKTKAEQFYSGDTDGK-RVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVANNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRATFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIKKQKGVLQKYAEKLIAEGAVTRQEYEEEIAKYDKICEEAHSRSKDEKILHIKHWLDSPWPGFFT-LDGQPKSISCPSTGLPEEELAQIGQVASSVP--VEDFTIHGGLSRILKGRGDMIKN-RTVDWALGEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRICIPMNHMSPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDFNPKITD-DFDVRQLYDCNWIVVNCSNPANYFHVIRRQILLPFRKPLIVFTPKSLLRHPEAKSNFDQMLPGTHFQRVIT--DDGPPAQNPSEVKRIVFCTGKIYYELTRERKARNMENSVAITRIEQLSPFPFDLVRAETEKFPN-ADLVWCQEEHKNQGYYDYVKPRMRTTINRT-------------------------------------------------------------------------------------------------KPVWYAGREPAAAPATGNKNTHLLELKRFLDTAFNLDAFKDHI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ULD0-1", "uniprot_id": "OGDHL_HUMAN", "id": "Q9ULD0-1", "name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "aln": "----MSQLRLLPSRLG----VQAARLLAAHDVPVF---GWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRP-------PSVVHESRSAVSSRTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPT---TTFIGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAAD-EGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGK-KVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFN-VDGEPKSMTCPATGIPEDMLTHIGSVASSVP--LEDFKIHTGLSRILRGRADMTKN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTK-DFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIP--EDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPG-AELAWCQEEHKNMGYYDYISPRFMTILRRA-------------------------------------------------------------------------------------------------RPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZQD3-1", "uniprot_id": "OGDHL_RAT", "id": "D3ZQD3-1", "name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "aln": "----MSQLRLLLFRLG----PQARKLLATRDIAAF---GGRRRSSGPPTTIPRSRGGVSPSYVEEMYFAWLENPQSVHKSWDNFFQRATKEASVGPAQPQP-------PAVIQESRASVSSCTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFRLPT---TTFIGGSENTLSLREIIRRLESTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMKFSIEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGVENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAAD-EGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGR-KVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHKQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFN-VDGEPKSMTYPTTGIPEDTLSHIGNVASSVP--LEDFKIHTGLSRILRGRADMTKK-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQDVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPVFTE-DFEVSQLYDCNWIVVNCSTPASYFHVLRRQVLLPFRKPLIVFTPKSLLRHPDAKSSFDQMVSGTSFQRMIP--EDGPAAQSPERVERLIFCTGKVYYDLVKERSSQGLEKQVAITRLEQISPFPFDLIMREAEKYSG-AELVWCQEEHKNMGYYDYISPRFMTLLGHS-------------------------------------------------------------------------------------------------RPIWYVGREPAAAPATGNKNTHLVSLRKFLDTAFNLKAFEGKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8JNU6-1", "uniprot_id": "A8JNU6_DROME", "id": "A8JNU6-1", "name": "2-oxoglutarate dehydrogenase, mitochondrial", "aln": "MHRAHTAFSLALSPMAHKNFATWLLKSSSSQQMAKVTAAAAVRTYNS-AAAEPFANGSTASYVEEMYNAWLRDPTSVHTSWDAYFRSNSYVSPPNLAPVQANTLP---LTAFNFGGAVAGAAP-DSKTIDDHLAVQAIIRSYQIRGHNIAHLDPLEINTPELPGNSSTKSIYAN-----FSFGEQDMDRQFKLPS---TTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVCRKPLNQIFTQFAG-LEAAD-DGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDQEGK-KVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGFFE-GKD---PLKVAPTGVKEETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDE-KVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPESD-EFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIP--DNGPAGQNPSNVKKVVFCSGRVYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKEQANLYKN-AELVWAQEEHKNQGSWTYVQPRFLTALNHSRDVSQSDEQSSSTNTTTTTDHTNHESDTDSDSKSKPWLSRMFAAPNSSTGGDPKDPAQTLGGDFNAAKHFDLKNVRHDFNRPAGIAAAPGARIAKTGRKISYVGRACGASTATGSKAQHIRELNALLNDAIST--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20967-1", "uniprot_id": "ODO1_YEAST", "id": "P20967-1", "name": "2-oxoglutarate dehydrogenase, mitochondrial", "aln": "------MLRFVSSQTCRYS-SRGLLKTSLLKNAST---VKIVGRGLATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQGTEAAPLGTAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGIS----FGSNKNNPVPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQRP-TTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKD-YVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPESTLKELGKVLSSWP---EGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSE-AIYTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPSEEK---LQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTEG-GFQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHK-RRESLGDKTTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKET--------------------------------------------------------------------------------------------DKYKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVFQQS-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . ..*::*** ** .:* *** *** :*: . . . . .: :. ** ** : *:**:*** *::*** * . . : . :.: : *:*: :.* . . * . : :.*:**: :** **. *::: .* . ::*:*:*:::* * ::: ::** :* *:. : ** ** *:..:******* * ::*.:* ::* * *:: :::**.******.*:** ** :.** :* * :****:***** .* .:.: : *::********: :*** *:*:* . .* . : :.:.:*:******.***:****: : **.*:* **:**:.***********::**:** :*:*:.::*******::* *** .: .:***** .*:.* ::*:* :*:.**** *:* *******::* :: :. *:: *:::*... : .. .: *:*. :* :.** :.* ** . : .*.: *. * .:*. ** * * :* .* *:* * . *** .* :***:*: :* ::*:**:********:** ***.* : .:. : ::* :::.*******.*:*** *::::.*: **:******** * ** ******. *: ** ::.*:*: **** :* ****** * *****:..:*. * . * * *: *. :.*.. :*::*** ***** : .*.***** *:: :.:: * ** :* :.* . ..::::: :*::* * : * *: ::**: **** : . : : . ::.*.*** * * : * .**: * : .: : * ** ..: *:*.: *: . :*. .:. ", "identical_positions": 347, "similar_positions": 298, "identity": "30.49%" }, { "cls_id": "homologset.agr.FB:FBgn0010355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7M0-1", "uniprot_id": "A0A8I6A7M0_RAT", "id": "A0A8I6A7M0-1", "name": "Transcription initiation factor TFIID subunit", "aln": "MGPGWAGLLPEDGSGSPSAVMSDTDSDEDSAGGGPFSLTGFLFGNINGAGQLE--------GESVLDDECKKHLAGLGALGLGSLITELTANEELSG---TDGTLVNDEGWIRSREDAVDYSDINEVAEDESRRYQQTMGSLQPLCHTDYDEDDYDADCEDIDCKLMPPPPPPPGPVKKERDQD--GITGVSEDGEGIILPSIIAPSSLASEKVDFSSSSDSESEMG-PQEATQSESKDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGK--NVPSVWRSARRKRKKKHRELIQEEQIQ--EEECSVELEVNQKSLWNYDYAPPPLPEQCLSDDEITMMAPVESKFSQSTG-DTDKVMDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKMKKTEHDSTMKYNIMKKLRKLEE--------------NNGVDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQ--RASLAGWLPSSMTRNAMAYN-------------VQQGFTAT---------------------------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQNMPRILEPPVLTLDPNDENLILEIPDEKE----EATSNSPSKENKKESSLKKSRILLGKTGVIKEEPQQNMSQPE---VKDPWNLSNDEYYYPKQQ-GLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSP-----FLGSLHPGQLLQAFENNLFRAPIYLHKMPESDFLIIRTR-----QGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSA-EDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAG--------------SAAGGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKAAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKK-----------------------------------PKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIES--ADEVRRKS-----LVLKFPKQQLPPKKKRRVGTTVHCDYLN--RPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCHQTLTEYDEHLTQLEKDICTAKEAALEEA--------------ELESLDPMTPGPYTPQAKPPDLYDNSTSLSVSRDASVYQD-------------------------ESNLSVLDIPSATSEKQ-------------LTQ--------------EGGD-----------------------------------------------------------GDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEE----------------------------DAGSDEEGDN-PFSAIQLSESGSD-----SDVESGSIRPKQPRMLQENTRMGMENEESMMSYEGDGGEASRGLEDSNISYGSYEEPDPKS-NTQDTSFSSIGG-----YEVSEEEEDEEE---QRSGPSVLSQVQLSEDEEDSEDLHSIAGDSDLDSDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UV9-1", "uniprot_id": "TAF1_MOUSE", "id": "Q80UV9-1", "name": "Transcription initiation factor TFIID subunit 1", "aln": "MGPGWAGLLQDKGGGSPSVVMSDTDSDEESAGGGPFSLTGFLFGNINGAGQLE--------GESVLDDECKKHLAGLGALGLGSLITELTANEELSG---SDGALVNDEGWIRSREDAVDYSDINEVAEDESRRYQQTMGSLQPLCHTDYDEDDYDADCEDIDCKLMPPPPPPPGPLKKEKDQD--DITGVSEDGEGIILPSIIAPSSLASEKVDFSSSSDSESEMG-PQDAAQSESKDGQLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGK--NVPSVWRSARRKRKKKHRELIQEGQVQ--EEECSVELEVNQKSLWNYDYAPPPLPDQCLSDDEITMMAPVESKFSQSTG-DTDKVMDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKMKKTEHESTIKCNIMKKLRKLEE--------------NSGVDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQ--RASLAGWLPSSMTRNAMAYN-------------VQQGFTAT---------------------------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQNMPRILEPPVLTLDPNDENLILEIPDEKE----EATSNSPSKENKKESSLKKSRILLGKTGVIKEEPQQNMSQPE---VKDPWNLSNDEYYYPKQQ-GLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSP-----FLGSLHPGQLLQAFENNLFRAPIYLHKMPESDFLIIRTR-----QGYFIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSA-EDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAG--------------SAAAGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKATVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKK-----------------------------------PKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIES--ADEVRRKS-----LVLKFPKQQLPPKKKRRVGTTVHCDYLN--RPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVSPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCHQTLTEYDEHLTQLEKDICTAKEAALEEA--------------ELESLDPMTPGPYTPQ--PPDLYDNNTSLSVSRDASVYQD-------------------------ESNLSVLDIPSATSEKQ-------------LTQ--------------EGGD-----------------------------------------------------------GDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEE----------------------------DAGSDEEGDN-PFFAIQLSESGSD-----SDVESGSLRPKQPRVLQENTRMGMENEESMMSYEGDGGDASRGLEDSNISYGSYEEPDPKS-NTQDTSFSSIGG-----YEVSEEEEDEEE---QRSGPSVLSQVHLSEDEEDSEDFHSIAGDTDLDSDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21675-2", "uniprot_id": "TAF1_HUMAN", "id": "P21675-2", "name": "Transcription initiation factor TFIID subunit 1", "aln": "MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLE--------GESVLDDECKKHLAGLGALGLGSLITELTANEELTG---TDGALVNDEGWVRSTEDAVDYSDINEVAEDESRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQD--SITGVSENGEGIILPSIIAPSSLASEKVDFSSSSDSESEMG-PQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGK--NVPSVWRSARRKRKKKHRELIQEEQIQ--EVECSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTG-DIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEE--------------NNGTDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQ--RASLAGWLPSSMTRNAMAYN-------------VQQGFAAT---------------------------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKE----EATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPE---VKDPWNLSNDEYYYPKQQ-GLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSP-----FLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTR-----QGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSA-EDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAG--------------SAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKK-----------------------------------PKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIES--ADEVRRKS-----LVLKFPKQQLPPKKKRRVGTTVHCDYLN--RPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEA--------------ELESLDPMTPGPYTPQ--PPDLYDTNTSLSMSRDASVFQD-------------------------ESNMSVLDIPSATPEKQ-------------VTQ--------------EGED-----------------------------------------------------------GDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEE----------------------------DAGSDEEGDN-PFSAIQLSESGSD-----SDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKS-NTQDTSFSSIGG-----YEVSEEEEDEEEE-EQRSGPSVLSQVHLSEDEEDSEDFHSIAGDSDLDSDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IZX4-1", "uniprot_id": "TAF1L_HUMAN", "id": "Q8IZX4-1", "name": "Transcription initiation factor TFIID subunit 1-like", "aln": "MRPGCDLLLRAAATVT-AAIMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLE--------GESVLDDECKKHLAGLGALGLGSLITELTANEELTG---TGGALVNDEGWIRSTEDAVDYSDINEVAEDESQRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQD--AITCVSESGEDIILPSIIAPSFLASEKVDFSSYSDSESEMG-PQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLHLFGPGK--NVPSVWRSARRKRKK-HRELIQEEQIQ--EVECSVESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTG-DVDKVTDTKPRVAEWRYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEE--------------SNGTDLLADENFLMVTQLHWEDSIIWDGEDIKHKGTKPQ--GASLAGWLPSIKTRNVMAYN-------------VQQGFAPT---------------------------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKE----EATSNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPE---VKDPWNLSNDEYYFPKQQ-GLRGTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSP-----FLGSLHPGQLLQALENNLFRAPVYLHKMPETDFLIIRTR-----QGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAKVSPEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSISA-EDSDFEEMGKNIENMLQNKKTSSQLSREWEEQERKELRRMLLVAG--------------SAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKK-----------------------------------PKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIEN--VHEVRRKS-----LVLKFPKQQLPPKKKRRVGTTVHCDYLN--IPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALEEA--------------ELESLDPMTPGPYTSQ--PPDMYDTNTSLSTSRDASVFQD-------------------------ESNLSVLDISTATPEKQ-------------MCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPEG--------------------------------------------GDGDLADEEEGTVQQPEASVLYEDLLISEGEDDEE----------------------------DAGSDEEGDN-PFSAIQLSESGSD-----SDVGYGGIRPKQPFMLQHAS-------------------------------GEHKDGHGK----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q3C1-1", "uniprot_id": "A0A8M9Q3C1_DANRE", "id": "A0A8M9Q3C1-1", "name": "Transcription initiation factor TFIID subunit", "aln": "--------------------MSDSDSDEDQD--RPFHLTGFLFGNINENGQLE--------DDSVLDTESKKHLAGLGTLGLGSLITEITASEEETAEQEQDQSSTDAEGWVRSTEDAVDYSDISEVAEDETRKYRQAMGNLQPSRRTD-DEDDYDADCEDVDSKLMPPPPPPTQPITAKKDDTPTQNSSVTDEGDGIILPSIIAPSSVG-DKVDFSSSSDSESESDRPSQGSGTGKKAGCLTLPLAGIMQKDAAKALPGVTELFPEFRPGKVLRFLRLFGPGK--NMPSVWRSARRKRKRKQKEPQSDMAAAGDIESLPSEPGAKKKSGWDYEYAPPPPPEQCLSDDEITMMAPVESKFMQVSG-EGDKVSEMRPKVAEWRYGPAQLWYDMLGVPEDGSGFHYGFKLKDDKQEDNTDAVTKMATPPASEPVPEQEPPQESQDKADEDAPMQDELFLMVTQLQWEEDIIWNGEDVKHKGTKTQ--RASLAGWLPTSMTRNANAYN-------------AQQGLSRSNSQLVPPTPPPLTKTPSITGSKRDKHNHDHQVSHEDDTPWFSIFPIDNEELVYGRWEDNIIWDDQNMDCIPSPPVLTLNPNDENIILEIPDEKE----ERTSHSPSKENKKETALKKSRILLGKTGVIKDEPQQNMSQPE---IKDPWNLSNDEFYYPKQQ-GLRGSFGGNIIQHSIPTVELRQPFFPTHMGPMKLRQFHRPSLKKYSFGALSQPGPHAVQPLLKHIKKKAKMREQERQASGGGDMFFMRTAQDLTGKDGDLVLAEYSEEYPPLHMQVGMASKIKNYYKRKPGKDPGAPDCKYGETVYCHTSP-----FLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTR-----QGYFIRELVDIFVVGQECPLYEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKPDFRLPTEEEIRAMVSPEQCCAYYSMLVAEQRLKDAGYGEKSFFAPEEENEEEFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKVPNKPTQQKDDREPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLESTEVLSTDTDSSSA-EDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLMGEDNERERGRKERRKGSSALSTSSHKDDDASSVTSLNSSATGRRLKIYRTFCDEDGKEYVRCETVRKPAVIDAYLRIRTTKDDEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKDRFKGPPEKK-----------------------------------TKKAKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIES--ADEVRRKS-----LVLKFPKQQLPPKKKRRVGTTVHCDYLNVRRPHKSIHRRRTDPMVTLSSVLESIINDMRDLPNTYPFHTPVNGKVVKDYYKIITRPMDLQTLRENVRKRMYPSREEFRESVELIFKNSATYNGAKHPLTVVAQAMLSLCVEKIKEKEERLVRLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIINPMDLDTLRKNISKHKYQNREVFLSDVGLIHTNSVKYNGPDSPYTKTALEIVNVCKQTLAEYDEHLTQLEKDILTAKEAALDAA--------------DLESLDPLTPGPYTPQ---PDVCENSVSVSLQGDSSLLAEATLIPPTPEKRGGQG-RHRGRLGEEESDVDIEGFEEDDDGKP-------------KTPAP-HFQVEDGDLDDEDDDDEDDELLMRPPRRMH--------------------------------------------IDEDDDDDDEGSSRPAQASVLYQDLLMSDAEDD--------------------------------ASEEEGDN-PFSSIQLSESGSD-----SDADLG---------HQESTRIGLEQEESMMSYEGEGPDGLTHMEDSNVSFGSYDDGDSQM-QRQVSSPRTGERDVDEVYGISEEEEDEEEEDERRRGPSVLTQVQLSDDEEDSEEFRSVGGDSDMDSDN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51123-1", "uniprot_id": "TAF1_DROME", "id": "P51123-1", "name": "Transcription initiation factor TFIID subunit 1", "aln": "------------------MEMESDNSDDEGSIGNGLDLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEP-------PSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVK---AQDDAIDYSDITELSEDCPRTPPEETSTYDDLEDAIPASKVEAKLTKDDKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQN--VDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTG-GSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLLGDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTSSQPQLKDERRVKSPED--------------DVEDPSIADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGAS--------------------SKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGPMAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSP-----FLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTR-----NNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTGCGEGFSYVRVPNKPTQTKEEQESQP-KRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDLEELGKNLENMLSNKKTSTQLSREREELERQELLRQLDEEHGGP----------SGSGGAKGAKGKDDPGQQMLATNNQGRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEMTMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAMG-KKKRRVGGDLHCDYLQ--RHNKTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDKLHSQ-IKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQAYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDDGSRVRIKKEVFDDGDYALQHQQMGQAASQSQIYMVDSSNEPTTLDYQQPPQLDFQQVQEMEQLQHQVMPPMQSEQLQQQQTPQGDNDYAWTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46677-1", "uniprot_id": "TAF1_YEAST", "id": "P46677-1", "name": "Transcription initiation factor TFIID subunit 1", "aln": "--------------------MVKQQGSGKTNLANEDEAYEAIFG------------------------------GEFGSLEIGSYIGGDEG--------------ANSKDYTEHLPDAVDFEDEDELADDDDDLPEESDANLHPAMMTMGAYDDVNENGAVLGIDSN------SLNMQLPEINGDLSQQFILEDDGGTPATSNALFMGMDANEIHLATETGVLDGSG--------ANEIGHSQLSIGGVNGNDMSINGGFIMEPDMSDGKHKKATKLDLINHEK-YLLKKYFPDFEKGKILKWNKLIYRRSVP---------------YHWHSEISRVKKP-----------FMPLNLKFKVQQDDKRLFNSRTISYVAPIYQGKNNLLQSNSSASRRG--------LIHVSIDELFPIKEQQKKRKIIH-----------------DEKTISEDLLIATDDWDQEKIINQG-------------TSSTATLADSSMTPNLKFSG------------------------------------------------------------GYKLKSLIEDVAEDWQWDEDMIIDAK----LKESKHAELNMNDEKLLLMIEKTNN-------------LAQQKQQLDSSNLILPLNETILQQKFNLSNDDK------------YQILKKTHQTKVRSTISNLNIQHSQPAINLQSPFYKVAVPRYQLRHFHR-----ENFGSHIRPGTKIVFSKLKARKRKRDKGKDVKES-------FSTSQDLTIGDTAPVYLMEYSEQTPVALSKFGMANKLINYYRKANEQDTLRPKLPVGETHVLGVQDKSPFWNFGFVEPGHIVPTLYNNMIRAPVFKHDISGTDFLLTKSSGFGISNRFYLRNINHLFTVGQTFPVEEIPGPNSRKVTSMKATRLKMIIYRILN--HNHSKAISIDPIAKHFPDQDYGQNRQKVKEFMKYQRDGPEKGLWRLKDDEKLLDNEAVKSLITPEQISQVESMSQGLQFQEDN-----------EAYNFDSKLKSLEEN-LLPWNITKNFINSTQMRAMIQIHGVGDPTGCGEGFSFLKTSMKGGFVK--------------------------------------------------------SGSPSSNNNSSNKKGTNTHSYNVAQQQKAYDEEIAKTWYTHTKSLSISNPFEEMTN------PDEINQTNKHVKTDRDDKKILKIVRKKRDENGIIQRQTIFIRDP---------------------------------------RVIQGYIKIKEQD-KEDVNKLLEEDTSKINNLEELEKQKKLLQLELANLEKSQQRRAARQNSKRNGGATRTENSVDNGSDLAGVTDGK------------------------------------AARNKGKNTTRRCATCGQIGHIRTNKSCPMYSSKDNPASPK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :.. . :** . :. * :.* : : : .**. .: . : .. . :: * : . . : ... .. :. .: :. . . . .:..: . : * . * *:. * : . : .: : .. : . : * : .: : . . . ** * .: . .. * . . . .: :*:.:: ::.:: :* :. * : : . . :.: .: :: :*::::* * : : .. *: ***:::* * . : . :..*.::* .* : . : :* .... **** *.::* ** . : ::* *** ..*. :. .: * . ** :* . : : : * . : * . : * *:.*: :.**..*: ***:: :*. . **. .. :* :.**: : :: **: ***:: *.:. .***: :: : :::*.: ::.*** *: *:*****::.. *:::***:: ::..: * :: * : ** :. .. *:::* .::* * :.. * :* : :* :* ::: ::*** . ** . * :* * : : ::* :* *** *: :* : : :.:::: * .**********::: . * * * . : .: .* :. :.:*::*: *.** : : :.: * :: :. .:::: .*:::. .:** . : :: :* : : : :: .: :: ** .. . . *: .:.. *. :. ..:::. ::: :* * : :: . : .: : : : . :*.:** :**:**** **:* : . * ", "identical_positions": 162, "similar_positions": 356, "identity": "7.3%" }, { "cls_id": "homologset.agr.FB:FBgn0010356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH66-1", "uniprot_id": "D3ZH66_RAT", "id": "D3ZH66-1", "name": "Transcription initiation factor TFIID subunit 5", "aln": "MAALAEEQTEVAVKLESEGPPTLLPPQAGDGAGEGSGGTPNNGPNGGGGN---VAAAAGGDGGTPKPVVAVSAAAPAGAAPVPAAPAEAGAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPDTPGAGASVTSVFSGSASGPAAPGKVASVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHESEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQ---NNQIWNIVQEHLYIDIFDGMPR-----SKQQIDAMVGSLAGEAKREANKSKVFFG-------LLKEPEIE------------------------------------------VPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLG--PDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGH-TDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQ----------------ELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C092-1", "uniprot_id": "TAF5_MOUSE", "id": "Q8C092-1", "name": "Transcription initiation factor TFIID subunit 5", "aln": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTPNNGPNGGGGGNVAVAAAAGGDGGTPKPGVAVSAAAPAGAAPVPAAPAEAGAPHDRQTLLAVLQFLRQSNLREAEEALRREARLLEEAVAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPEPPGTGASVTSVFSGSASGPAAPGKVASVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRIYRDSYQLLKRHLQEKQ---NNQIWNIVQEHLYIDIFDGMPR-----SKQQIDAMVGSLAGEAKREANKSKVFFG-------LLKEPEIE------------------------------------------VPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLG--PDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGH-TDTVCSLRFSRDGEILASGSMDNTVRLWDAVKAFEDLETDDFTTATGHINLPENSQ----------------ELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15542-1", "uniprot_id": "TAF5_HUMAN", "id": "Q15542-1", "name": "Transcription initiation factor TFIID subunit 5", "aln": "MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGN-VAASSSTGGDGGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREAGLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASGPAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQ---NNQIWNIVQEHLYIDIFDGMPR-----SKQQIDAMVGSLAGEAKREANKSKVFFG-------LLKEPEIE------------------------------------------VPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLG--PDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGH-TDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQ----------------ELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49846-1", "uniprot_id": "TAF5_DROME", "id": "P49846-1", "name": "Transcription initiation factor TFIID subunit 5", "aln": "------------MSLEVSN------------------------INGGNGT---------------------------------------QLSHDKRELLCLLKLIKKYQLKSTEELLCQEANVSSVELS-------------EISESDVQQVLGAVLGAGDANRERK----------HVQSPAQGHKQSAVTEANAAEELAKFID-DDSFDAQHYEQAYKELRTFVEDSLDIYKHELSMVLYPILVQIYFKILASGLREKAKEFIEKYKCDLDGYYIEGLFNLLLLSKPEELLENDLVVAMEQDKFVIRMSRDSHSLFKRHIQDRR---QEVVADIVSKYLHFDTYEGMAR-----NKLQCVATAGSHLGEAKRQDNKMRVYYG-------LLKEVDFQTLTTP-------------------------------------APAPEEEDDDPDAPDRPKKKKPKKDPLLSKKSKSDPNAPSIDRIPLPELKDSDKLLKLKALREASKRLALS--KDQLPSAVFYTVLNSHQGVTCAEISDDSTMLACGFGDSSVRIWSLTPAKLRTLKDADSLRELDKESADINVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGSLVTTLLRH-TSTVTTITFSRDGTVLAAAGLDNNLTLWDFHKVTEDYISNHITVS--HHQDENDED----------------VYLMRTFPSKNSPFVSLHFTRRNLLMCVGLFKS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38129-1", "uniprot_id": "TAF5_YEAST", "id": "P38129-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF5", "aln": "---MSQKQSTNQNQNGTHQPQPVKNQRTNNAAGANSGQQPQQQSQGQSQQ----------------------------------QGRSNGPFSASDLNRIVLEYLNKKGYHRTEAMLRAESGRTLTPQN---------------KQSPANTKTGKFPEQSSIPPNPG-----------KTAKPISNPTNLSSKRDAEGGIVSSGRLEGLNAPENYIRAYSMLKNWVDSSLEIYKPELSYIMYPIFIYLFLNLVAKN-PVYARRFFDRFSPDFKDFHGSEINRLFSVNSIDHIKENEVASAFQSHKYRITMSKTTLNLLLYFLNENESIGGSLIISVINQHLDPNIVESVTAREKLADGIKVLSDSENGNGKQNLEMNSVPVKLGPFPKDEEFVKEIETELKIKDDQEKQLNQQTAGDNYSGANNRTLLQEYKAMNNEKFKDNTGDDDKDKIKDKIAKDEEKKESELKVDGEKKDSNLSSPARDILPLPPKTALDLKLEIQKVKESRDAIKLDNLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLN--------------NPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEPFIGYLGDVTASINQDIKEYGRRRTVIPTSDLVASFYTKKTPVFKVKFSRSNLALAGGAFRP-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* . :*: :.: : :* * *: .: . . . . . : : . : . * . *. *: ::: **: :: *** ::**::: :::::: . *: *:::: * . :: . : * :.. :.: *: :. *: : : : : .*: .:::.. . : .::.::* : :.:. . : : . *: : : *. * * ::** : : . ::.:. : : ::** .: : .:....: .:*. : :*** . * :: ::*: . : *. *** :**. *: :.::. :.:**. : * ** ** :::**: .*. . :: . *. : * **:*.** :*:*: : *** *** *:****: * :.:* *:** :****. *:* *:**.: .:*:.****: * .**:*.*** **:*. :***. ** ***:*:* *:** .*:.**:: **...: *::... **:*::*: * : :**:. * : : * ..:: :: :*::* :* :.. *:.: :** *. : :: : . *: :: :*.:*.. ::*:* ** :. * : . ", "identical_positions": 146, "similar_positions": 255, "identity": "16.65%" }, { "cls_id": "homologset.agr.FB:FBgn0010357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKQ9-1", "uniprot_id": "KLK9_HUMAN", "id": "Q9UKQ9-1", "name": "Kallikrein-9", "aln": "------------MKLGLLCALLSL---------------LAGHGWA-------------------DTRAIGAEECRPNSQPWQAGLFHLT--RLFCGATLISDRWLLTAAHCRKPY--------LWVRLGEHHLW-KWEGPEQLFRVTDFFPHPGFNKDLSA-------NDHNDDIMLIRLPRQARLSPAVQPLNLSQTCV--SPGMQCLISGWGAVSSPKA----LFPVTLQCANISILENKLCHWA--------YPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNG-----TLAGVVSGG-AEPCSRPRRPAVYTSVCHYLDWIQEIMEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKR0-1", "uniprot_id": "KLK12_HUMAN", "id": "Q9UKR0-1", "name": "Kallikrein-12", "aln": "------------MGLS-IFLLLCV---------------LGLSQAA-------------------TPKIFNGTECGRNSQPWQVGLFEGT--SLRCGGVLIDHRWVLTAAHCSGSR--------YWVRLGEHSLS-QLDWTEQIRHSGFSVTHPGYLG--AS-------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCA--TAGTECHVSGWGITNHPRN----PFPDLLQCLNLSIVSHATCHGV--------YPGRITSNMVCAGGVPG-QDACQGDSGGPLVCGG-----VLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "-----------MLLLLTILQALAV---------------AIVQSQG-------------------DDKILGGYTCVQNSQPWQVALQAGPGRRFLCGGVLLSDQWVITAAHCARPL--------LHVALGKHNLR-RWEATQQVLRVVRQVPHPQYRP-----------QAHDNDLMLLKLQRKVRLGRAVRTIPVARSCA--SPGTPCRVSGWGTTASPIV----RYPTALQCVNVNIMPEQVCHRA--------YPGTITSGMVCAGVPEGGKDSCQGDSGGPLVCQG-----QLQGLVSWG-MERCAMPGYPGVYTNLCNYHSWIQRTMQSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5K2-1", "uniprot_id": "KLK4_HUMAN", "id": "Q9Y5K2-1", "name": "Kallikrein-4", "aln": "-MATAGNPWGWFLG----YLILGV---------------AGSLVSG------------------SCSQIINGEDCSPHSQPWQAALVM-EN-ELFCSGVLVHPQWVLSAAHCFQNS--------YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIASQCP--TAGNSCLVSGWGLLANGR------MPTVLQCVNVSVVSEEVCSKL--------YDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "MMVTARTPWGWFLG----CLILEV---------------TGASASS------------------VSSRIIQGQDCSPHSQPWQAALFS-ED-GFFCSGVLVHPQWVLSAAHCLQES--------YIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFND-----------PSFANDLMLIKLNESVIESNTIRSIPVATQCP--TPGDTCLVSGWGQLKNGK------LPSLLQCVNLSVASEETCRLL--------YDPVYHLSMFCAGGGQDQKDSCNGDSGGPIVCNR-----SLQGLVSMG-QGKCGQPGIPSVYTNLCKFTNWIQTIIQTN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRA7-1", "uniprot_id": "D3ZRA7_RAT", "id": "D3ZRA7-1", "name": "", "aln": "-MARAGHPWKWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPN-KLYCGAVLINPQWLLTAAHCRKPV--------FRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSH-----------PGHSNDLMLIKMNRKIRASHSVKPVEITSDCP--KEGTRCMVSGWGTTSSSHN----NFPKVLQCLDITVLSEERCKNS--------YPGQIDKTMFCAG-DEAGRDSCQGDSGGPVICNG-----KLQGLVSWG-DFPCAQPNRPGVYTNLCEFVPWIKDTIHSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "------------MWFLILFLALSLG-------------QIDAAPPG-------------------QSRVVGGYNCETNSQPWQVAVIG----TTFCGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLV-KDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEP--KVGSICLASGWGMTNPSE----MKLSHDLQCVNIHLLSNEKCIET--------YKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDG-----VLQGLTSGG-ATPCAKPKTPAIYAKLIKFTSWIKKVMKENP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMU8-1", "uniprot_id": "A0A8I6AMU8_RAT", "id": "A0A8I6AMU8-1", "name": "tissue kallikrein", "aln": "------------NFFLYFFLDQVII-------------EQNAAPPG-------------------QSRVVGGYKCEKNSQPWQVAVIS----RSLCGGVLIDPSWVITAAHCYSNY--------YHVLLGRNNLS-EDEPFAQYRFVSQSFPHPDYNPFFMRNHTRQPGDDYSNDLMLLHLSKPADITDGVKVIDLPTEEP--KVGSTCLASGWGSTKPLDYRMWLGSAHDPLCVNIHLLSNEKCIEA--------YNEKVTDLMLCAGDLEGGKDTCKGDSGGPLICDG-----VLQGITSWG-SDPCAEPNMPAIYTKLIKFTSWIKEVMKENS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35004-1", "uniprot_id": "TRYB_DROME", "id": "P35004-1", "name": "Trypsin beta", "aln": "-----------MLKFLILLSAVACALG-------------GTIPEG--------------LLPQLDGRIVGGTATTISSFPWQISLQRSGS--HSCGGSIYSARVIVTAAHCLQSV--------SASSLQIRAGSSYWSSGGVVAKVSSFKNHEGYNAN-----------TMVNDIAVLHLSSSLSFSSTIKAIGLASSNP--ANGAAASVSGWGTESSGSS----SIPSQLRYVNVNIVSQSRCSSSS-----YGYGNQIKSSMICAF--ASGKDSCQGDSGGPLVSGG-----VLVGVVSWG--YGCAAANYPGVYADVAALRSWVINNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "------------MKWCWGPVLLIAG---------ATVLMEGLQAAQ-----------RACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGA--HICSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYS------------QGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGW----DQDTS---DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFA--SSCAQEDAPVLLTNTAAHSSWLQARVQG----AAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR-------QAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGG----DGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEP-------EPEAEPGSCLANISQPTSC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "------------MRQSWRPELLIVG---------AVVVIEGLQAAQ-----------RACGQRGPGPPEPQEGNTLPGEWPWQASVRRQGV--HICSGSLVADTWVLTAAHCFEKMATAELS-SWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYS------------QGSDLALLQLTHPTVQT----TLCLPQPTYHFPFGASCWATGW----DQNTS---DVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFT--SKCAQEDTPVLLTDMAVHSSWLQAHVHE----AAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGR-------QTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLGPMACSRQHAAPGG----TGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLDWQVYFAEEP-------EPEAETGSCLVNSSQPASC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "-----------MARHLLLPLVMLVISPIPGAFQDSALSPTQEEPED-----------LDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVE------------LGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPL---PLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFG--FGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWD-NASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "-----------MSPHLFLPVVVLVVSPTPGAFQDSAVSPTQGEFED-----------LDCGRPEPSSRIVGGSDAHPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYSRVE------------LGADLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPL---PVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCED-GGRWFLAGITSFG--FGCGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDS------LHDFETWRVLLPSRPEEKRVVRLVAHENASRN-FASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLR---PRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALPLLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** .: *.. : :::**** * *: :::: : :. * . :** . : : . * .*. :..* ******::. *: * *. * : : *: ", "identical_positions": 27, "similar_positions": 35, "identity": "3.0%" }, { "cls_id": "homologset.agr.FB:FBgn0010358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKQ9-1", "uniprot_id": "KLK9_HUMAN", "id": "Q9UKQ9-1", "name": "Kallikrein-9", "aln": "-------------------MKLGLLCALLSL---------------LAGHGWA-------------------DTRAIGAEECRPNSQPWQAGLFHLT--RLFCGATLISDRWLLTAAHCRKPY--------LWVRLGEHHLW-KWEGPEQLFRVTDFFPHPGFNKDLSA-------NDHNDDIMLIRLPRQARLSPAVQPLNLSQTCV--SPGMQCLISGWGAVSSPKA----LFPVTLQCANISILENKLCHW--------AYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNG-----TLAGVVSGG-AEPCSRPRRPAVYTSVCHYLDWIQEIMEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKR0-1", "uniprot_id": "KLK12_HUMAN", "id": "Q9UKR0-1", "name": "Kallikrein-12", "aln": "-------------------MGLS-IFLLLCV---------------LGLSQAA-------------------TPKIFNGTECGRNSQPWQVGLFEGT--SLRCGGVLIDHRWVLTAAHCSGSR--------YWVRLGEHSLS-QLDWTEQIRHSGFSVTHPGYLG--AS-------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCA--TAGTECHVSGWGITNHPRN----PFPDLLQCLNLSIVSHATCHG--------VYPGRITSNMVCAGGVPG-QDACQGDSGGPLVCGG-----VLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "------------------MLLLLTILQALAV---------------AIVQSQG-------------------DDKILGGYTCVQNSQPWQVALQAGPGRRFLCGGVLLSDQWVITAAHCARPL--------LHVALGKHNLR-RWEATQQVLRVVRQVPHPQYRP-----------QAHDNDLMLLKLQRKVRLGRAVRTIPVARSCA--SPGTPCRVSGWGTTASPIV----RYPTALQCVNVNIMPEQVCHR--------AYPGTITSGMVCAGVPEGGKDSCQGDSGGPLVCQG-----QLQGLVSWG-MERCAMPGYPGVYTNLCNYHSWIQRTMQSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5K2-1", "uniprot_id": "KLK4_HUMAN", "id": "Q9Y5K2-1", "name": "Kallikrein-4", "aln": "-MATAGNPW-------GWFLG----YLILGV---------------AGSLVSG------------------SCSQIINGEDCSPHSQPWQAALVM-EN-ELFCSGVLVHPQWVLSAAHCFQNS--------YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIASQCP--TAGNSCLVSGWGLLANGR------MPTVLQCVNVSVVSEEVCSK--------LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "MMVTARTPW-------GWFLG----CLILEV---------------TGASASS------------------VSSRIIQGQDCSPHSQPWQAALFS-ED-GFFCSGVLVHPQWVLSAAHCLQES--------YIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFND-----------PSFANDLMLIKLNESVIESNTIRSIPVATQCP--TPGDTCLVSGWGQLKNGK------LPSLLQCVNLSVASEETCRL--------LYDPVYHLSMFCAGGGQDQKDSCNGDSGGPIVCNR-----SLQGLVSMG-QGKCGQPGIPSVYTNLCKFTNWIQTIIQTN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRA7-1", "uniprot_id": "D3ZRA7_RAT", "id": "D3ZRA7-1", "name": "", "aln": "-MARAGHPW-------KWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPN-KLYCGAVLINPQWLLTAAHCRKPV--------FRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSH-----------PGHSNDLMLIKMNRKIRASHSVKPVEITSDCP--KEGTRCMVSGWGTTSSSHN----NFPKVLQCLDITVLSEERCKN--------SYPGQIDKTMFCAG-DEAGRDSCQGDSGGPVICNG-----KLQGLVSWG-DFPCAQPNRPGVYTNLCEFVPWIKDTIHSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "-------------------MWFLILFLALSLG-------------QIDAAPPG-------------------QSRVVGGYNCETNSQPWQVAVIG----TTFCGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLV-KDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEP--KVGSICLASGWGMTNPSE----MKLSHDLQCVNIHLLSNEKCIE--------TYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDG-----VLQGLTSGG-ATPCAKPKTPAIYAKLIKFTSWIKKVMKENP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMU8-1", "uniprot_id": "A0A8I6AMU8_RAT", "id": "A0A8I6AMU8-1", "name": "tissue kallikrein", "aln": "-------------------NFFLYFFLDQVII-------------EQNAAPPG-------------------QSRVVGGYKCEKNSQPWQVAVIS----RSLCGGVLIDPSWVITAAHCYSNY--------YHVLLGRNNLS-EDEPFAQYRFVSQSFPHPDYNPFFMRNHTRQPGDDYSNDLMLLHLSKPADITDGVKVIDLPTEEP--KVGSTCLASGWGSTKPLDYRMWLGSAHDPLCVNIHLLSNEKCIE--------AYNEKVTDLMLCAGDLEGGKDTCKGDSGGPLICDG-----VLQGITSWG-SDPCAEPNMPAIYTKLIKFTSWIKEVMKENS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKA2-1", "uniprot_id": "TRYDT_DROME", "id": "C0HKA2-1", "name": "Trypsin delta", "aln": "-MLKFVILLSAVACALG------------------------------GTVPEG--------------LLPQLDGRIVGGSATTISSFPWQISLQRSGS--HSCGGSIYSSNVIVTAAHCLQSV--------SASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNAN-----------TMVNDIAIIKINGALTFSSTIKAIGLASSNP--ANGAAASVSGWGTLSYGSS----SIPSQLQYVNVNIVSQSQCASST-----YGYGSQIRSTMICAA--ASGKDACQGDSGGPLVSGG-----VLVGVVSWG--YGCAYSNYPGVYADVAALRSWVISNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "-MKWCWGPVLLIAG---------ATVLMEGLQ--------------AAQRACG---------------QRGPGPPKPQEGNTVPGEWPWQASVRRQGA--HICSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYS------------QGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGW----DQDTS---DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFA--SSCAQEDAPVLLTNTAAHSSWLQARVQG----AAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR-------QAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGG----DGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEP-------EPEAEPGSCLANISQPTSC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "-MRQSWRPELLIVG---------AVVVIEGLQ--------------AAQRACG---------------QRGPGPPEPQEGNTLPGEWPWQASVRRQGV--HICSGSLVADTWVLTAAHCFEKMATAELS-SWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYS------------QGSDLALLQLTHPTVQT----TLCLPQPTYHFPFGASCWATGW----DQNTS---DVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFT--SKCAQEDTPVLLTDMAVHSSWLQAHVHE----AAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGR-------QTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLGPMACSRQHAAPGG----TGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLDWQVYFAEEP-------EPEAETGSCLVNSSQPASC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "MARHLLLPLVMLVISPIPGAFQDSALSPTQEE--------------PEDLDCG---------------RPEPSARIVGGSNAQPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVE------------LGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPL---PLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFG--FGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWD-NASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "MSPHLFLPVVVLVVSPTPGAFQDSAVSPTQGE--------------FEDLDCG---------------RPEPSSRIVGGSDAHPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYSRVE------------LGADLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPL---PVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCED-GGRWFLAGITSFG--FGCGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDS------LHDFETWRVLLPSRPEEKRVVRLVAHENASRN-FASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLR---PRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALPLLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *** .: *.. : :::**** * *: :::: : :. * . :** . : : . * .*.. :..* ******::. *: * *. * : : *: ", "identical_positions": 27, "similar_positions": 37, "identity": "2.97%" }, { "cls_id": "homologset.agr.FB:FBgn0010359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKQ9-1", "uniprot_id": "KLK9_HUMAN", "id": "Q9UKQ9-1", "name": "Kallikrein-9", "aln": "-------------------MKLGLLCALLSL---------------LAGHGWA-------------------DTRAIGAEECRPNSQPWQAGLFHLT--RLFCGATLISDRWLLTAAHCRKPY--------LWVRLGEHHLW-KWEGPEQLFRVTDFFPHPGFNKDLSA-------NDHNDDIMLIRLPRQARLSPAVQPLNLSQTCV--SPGMQCLISGWGAVSSPKA----LFPVTLQCANISILENKLCHW--------AYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNG-----TLAGVVSGG-AEPCSRPRRPAVYTSVCHYLDWIQEIMEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKR0-1", "uniprot_id": "KLK12_HUMAN", "id": "Q9UKR0-1", "name": "Kallikrein-12", "aln": "-------------------MGLS-IFLLLCV---------------LGLSQAA-------------------TPKIFNGTECGRNSQPWQVGLFEGT--SLRCGGVLIDHRWVLTAAHCSGSR--------YWVRLGEHSLS-QLDWTEQIRHSGFSVTHPGYLG--AS-------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCA--TAGTECHVSGWGITNHPRN----PFPDLLQCLNLSIVSHATCHG--------VYPGRITSNMVCAGGVPG-QDACQGDSGGPLVCGG-----VLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "------------------MLLLLTILQALAV---------------AIVQSQG-------------------DDKILGGYTCVQNSQPWQVALQAGPGRRFLCGGVLLSDQWVITAAHCARPL--------LHVALGKHNLR-RWEATQQVLRVVRQVPHPQYRP-----------QAHDNDLMLLKLQRKVRLGRAVRTIPVARSCA--SPGTPCRVSGWGTTASPIV----RYPTALQCVNVNIMPEQVCHR--------AYPGTITSGMVCAGVPEGGKDSCQGDSGGPLVCQG-----QLQGLVSWG-MERCAMPGYPGVYTNLCNYHSWIQRTMQSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5K2-1", "uniprot_id": "KLK4_HUMAN", "id": "Q9Y5K2-1", "name": "Kallikrein-4", "aln": "-MATAGNPW-------GWFLG----YLILGV---------------AGSLVSG------------------SCSQIINGEDCSPHSQPWQAALVM-EN-ELFCSGVLVHPQWVLSAAHCFQNS--------YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIASQCP--TAGNSCLVSGWGLLANGR------MPTVLQCVNVSVVSEEVCSK--------LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "MMVTARTPW-------GWFLG----CLILEV---------------TGASASS------------------VSSRIIQGQDCSPHSQPWQAALFS-ED-GFFCSGVLVHPQWVLSAAHCLQES--------YIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFND-----------PSFANDLMLIKLNESVIESNTIRSIPVATQCP--TPGDTCLVSGWGQLKNGK------LPSLLQCVNLSVASEETCRL--------LYDPVYHLSMFCAGGGQDQKDSCNGDSGGPIVCNR-----SLQGLVSMG-QGKCGQPGIPSVYTNLCKFTNWIQTIIQTN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRA7-1", "uniprot_id": "D3ZRA7_RAT", "id": "D3ZRA7-1", "name": "", "aln": "-MARAGHPW-------KWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPN-KLYCGAVLINPQWLLTAAHCRKPV--------FRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSH-----------PGHSNDLMLIKMNRKIRASHSVKPVEITSDCP--KEGTRCMVSGWGTTSSSHN----NFPKVLQCLDITVLSEERCKN--------SYPGQIDKTMFCAG-DEAGRDSCQGDSGGPVICNG-----KLQGLVSWG-DFPCAQPNRPGVYTNLCEFVPWIKDTIHSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "-------------------MWFLILFLALSLG-------------QIDAAPPG-------------------QSRVVGGYNCETNSQPWQVAVIG----TTFCGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLV-KDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEP--KVGSICLASGWGMTNPSE----MKLSHDLQCVNIHLLSNEKCIE--------TYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDG-----VLQGLTSGG-ATPCAKPKTPAIYAKLIKFTSWIKKVMKENP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMU8-1", "uniprot_id": "A0A8I6AMU8_RAT", "id": "A0A8I6AMU8-1", "name": "tissue kallikrein", "aln": "-------------------NFFLYFFLDQVII-------------EQNAAPPG-------------------QSRVVGGYKCEKNSQPWQVAVIS----RSLCGGVLIDPSWVITAAHCYSNY--------YHVLLGRNNLS-EDEPFAQYRFVSQSFPHPDYNPFFMRNHTRQPGDDYSNDLMLLHLSKPADITDGVKVIDLPTEEP--KVGSTCLASGWGSTKPLDYRMWLGSAHDPLCVNIHLLSNEKCIE--------AYNEKVTDLMLCAGDLEGGKDTCKGDSGGPLICDG-----VLQGITSWG-SDPCAEPNMPAIYTKLIKFTSWIKEVMKENS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HKA3-1", "uniprot_id": "TRYGT_DROME", "id": "C0HKA3-1", "name": "Trypsin gamma", "aln": "-MLKFVILLSAVACALG------------------------------GTVPEG--------------LLPQLDGRIVGGSATTISSFPWQISLQRSGS--HSCGGSIYSSNVIVTAAHCLQSV--------SASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNAN-----------TMVNDIAIIKINGALTFSSTIKAIGLASSNP--ANGAAASVSGWGTLSYGSS----SIPSQLQYVNVNIVSQSQCASST-----YGYGSQIRSTMICAA--ASGKDACQGDSGGPLVSGG-----VLVGVVSWG--YGCAYSNYPGVYADVAALRSWVISNA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "-MKWCWGPVLLIAG---------ATVLMEGLQ--------------AAQRACG---------------QRGPGPPKPQEGNTVPGEWPWQASVRRQGA--HICSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYS------------QGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGW----DQDTS---DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFA--SSCAQEDAPVLLTNTAAHSSWLQARVQG----AAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR-------QAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGG----DGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEP-------EPEAEPGSCLANISQPTSC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "-MRQSWRPELLIVG---------AVVVIEGLQ--------------AAQRACG---------------QRGPGPPEPQEGNTLPGEWPWQASVRRQGV--HICSGSLVADTWVLTAAHCFEKMATAELS-SWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYS------------QGSDLALLQLTHPTVQT----TLCLPQPTYHFPFGASCWATGW----DQNTS---DVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFT--SKCAQEDTPVLLTDMAVHSSWLQAHVHE----AAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGR-------QTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLGPMACSRQHAAPGG----TGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLDWQVYFAEEP-------EPEAETGSCLVNSSQPASC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "MARHLLLPLVMLVISPIPGAFQDSALSPTQEE--------------PEDLDCG---------------RPEPSARIVGGSNAQPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVE------------LGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPL---PLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFG--FGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWD-NASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "MSPHLFLPVVVLVVSPTPGAFQDSAVSPTQGE--------------FEDLDCG---------------RPEPSSRIVGGSDAHPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYSRVE------------LGADLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPL---PVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCED-GGRWFLAGITSFG--FGCGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDS------LHDFETWRVLLPSRPEEKRVVRLVAHENASRN-FASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLR---PRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALPLLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *** .: *.. : :::**** * *: :::: : :. * . :** . : : . * .*.. :..* ******::. *: * *. * : : *: ", "identical_positions": 27, "similar_positions": 37, "identity": "2.97%" }, { "cls_id": "homologset.agr.FB:FBgn0010379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63484-1", "uniprot_id": "AKT3_RAT", "id": "Q63484-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MSDVTIVKEDWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--VDLP-YPLNN--------------------FSVAKCQLMKTERPKPNTFIIRCLQWTTVIER----------------------TFHVDTPEEREE--------------WTEAIQAVADRLQ-------RQE--EERMNCSPTSQIDNIGEEEMDASTTHHK--------------------------------------------------------------------------------------RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKDDDDGMDCMDNERRPHFPQFSYSASGRE--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUA6-1", "uniprot_id": "AKT3_MOUSE", "id": "Q9WUA6-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--VDLP-YPLNN--------------------FSVAKCQLMKTERPKPNTFIIRCLQWTTVIER----------------------TFHVDTPEEREE--------------WTEAIQAVADRLQ-------RQE--EERMNCSPTSQIDNIGEEEMDASTTHHK--------------------------------------------------------------------------------------RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDDDGMDGMDNERRPHFPQFSYSASGRE--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y243-1", "uniprot_id": "AKT3_HUMAN", "id": "Q9Y243-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--VDLP-YPLNN--------------------FSVAKCQLMKTERPKPNTFIIRCLQWTTVIER----------------------TFHVDTPEEREE--------------WTEAIQAVADRLQ-------RQE--EERMNCSPTSQIDNIGEEEMDASTTHHK--------------------------------------------------------------------------------------RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXT6-1", "uniprot_id": "E7EXT6_DANRE", "id": "E7EXT6-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MNDLNVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD--ADLA-YPLNN--------------------FSVAKCQLMKTERPKPNTFIIRCLQWTTVIER----------------------TFHVDTPEERDE--------------WVEAIQMVADKLA-------KQE--EEGILCSPISQIENVNEEEMDTSTSHHK--------------------------------------------------------------------------------------RKTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS-AKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIKFPR-TLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTALDWQDVYDKKLVPPFMPQVSSETDTRYFDEEFTAQTITITPPEKYDEDGMDAADSERRPHFPQFSYSASGRE--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q60823-1", "uniprot_id": "AKT2_MOUSE", "id": "Q60823-1", "name": "RAC-beta serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA--PDQTLPPLNN--------------------FSVAECQLMKTERPRPNTFVIRCLQWTTVIER----------------------TFHVDSPDEREE--------------WMRAIQMVANSLK-------QRGPGEDAMDYKCGSPSDSSTSEMMEVAVNKARA-------------------------------------------------------------------------------------KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR---HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR-TLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYD--SLDPLELDQRTHFPQFSYSASIRE--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47197-1", "uniprot_id": "AKT2_RAT", "id": "P47197-1", "name": "RAC-beta serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA--PDQTLPPLNN--------------------FSVAECQLMKTERPRPNTFVIRCLQWTTVIER----------------------TFHVDSPDEREE--------------WIRAIQMVANSLK-------QRGPGEDAMDYKCGSPSDSSTSEMMEVAVSKARA-------------------------------------------------------------------------------------KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR---HPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHS-TDVVYRDIKLENLMLDKDGHIKITDFGLSKEGISDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR-TLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYD--SLGSLELDQRTHFPQFSYSASIRE--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31751-1", "uniprot_id": "AKT2_HUMAN", "id": "P31751-1", "name": "RAC-beta serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEA--PDQTLPPLNN--------------------FSVAECQLMKTERPRPNTFVIRCLQWTTVIER----------------------TFHVDSPDEREE--------------WMRAIQMVANSLK-------QRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARA-------------------------------------------------------------------------------------KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR---HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR-TLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYD--SLGLLELDQRTHFPQFSYSASIRE--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31750-1", "uniprot_id": "AKT1_MOUSE", "id": "P31750-1", "name": "RAC-alpha serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQD--VDQRESPLNN--------------------FSVAQCQLMKTERPRPNTFIIRCLQWTTVIER----------------------TFHVETPEEREE--------------WATAIQTVADGLK-------RQE--EETMDFRSGSPSDNSGAEEMEVSLAKPKH-------------------------------------------------------------------------------------RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR---HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDD--SMECVDSERRPHFPQFSYSASGTA--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47196-1", "uniprot_id": "AKT1_RAT", "id": "P47196-1", "name": "RAC-alpha serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQD--VEQRESPLNN--------------------FSVAQCQLMKTERPRPNTFIIRCLQWTTVIER----------------------TFHVETPEEREE--------------WTTAIQTVADGLK-------RQE--EETMDFRSGSPSDNSGAEEMEVALAKPKH-------------------------------------------------------------------------------------RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR---HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDD--SMECVDSERRPHFPQFSYSASGTA--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31749-1", "uniprot_id": "AKT1_HUMAN", "id": "P31749-1", "name": "RAC-alpha serine/threonine-protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQD--VDQREAPLNN--------------------FSVAQCQLMKTERPRPNTFIIRCLQWTTVIER----------------------TFHVETPEEREE--------------WTTAIQTVADGLK-------KQE--EEEMDFRSGSPSDNSGAEEMEVSLAKPKH-------------------------------------------------------------------------------------RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR---HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDD--SMECVDSERRPHFPQFSYSASGTA--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INB9-1", "uniprot_id": "AKT1_DROME", "id": "Q8INB9-1", "name": "RAC serine/threonine-protein kinase", "aln": "-MNYLPFVLQRRSTVVASAPAP--GSASRIPESPTTTGSNIINIIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSG------HALTEQTQVVKEGWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLNN--------------------FTVRGCQIMTVDRPKPFTFIIRGLQWTTVIER----------------------TFAVESELERQQ--------------WTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGV---------------------------------------------------------------------------------KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTN---HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS-QGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDND-YGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPR-NITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDPTG--PLGSIAEE--PLFPQFSYQGDMASTLGTSSHISTSTSLASMQ--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11792-1", "uniprot_id": "SCH9_YEAST", "id": "P11792-1", "name": "Serine/threonine-protein kinase SCH9", "aln": "MMNFFTSKSSNQDTGFSSQHQHPNGQNNGNNNSSTAGNDNGYPCKLVSSGPCASSNNGALFTNFTLQTATPTTAISQDLYAMGTTGITSENALFQMKSMNNGISSVNNNNSNTPTIITTSQEETNAGNVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPKNDSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHD-NDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLG-AIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMN-KHQPMMTATPLSPAMQAKFAGFTFVDESAIDEHVNNNRKFLQNSYFMEPGSFIPGNPNLPPDEDVIDDDGDEDINDGFNQEKNMNNSHSQMDFDGDQHMDDEFVSGRFEI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::. . ... :: : :.:. :. . . :*: .:: .: : . . .::: :: : .*.. . ::. *. : : : . * : . . . : ::*: *::*******:* ::* : **:*:* *:**: *:*:***: * .:* .: **: .**::*** * :* :* .**:**:**.:* *:*:*::** **:: ** :**. ::***:* **::** :*:* : ****.* .:. :*****.******:* *: * : **:*. **:::** ** **: .::: :: * . .::*** : :.:.:: *** ::*.:*** . .* :*: * ** : * : **: *** *:: *:.** ** *** . . *. *:: . ", "identical_positions": 130, "similar_positions": 153, "identity": "15.68%" }, { "cls_id": "homologset.agr.FB:FBgn0010380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63010-1", "uniprot_id": "AP2B1_HUMAN", "id": "P63010-1", "name": "AP-2 complex subunit beta", "aln": "----------------MTDSKYFTTNK----KGEIFELKAELNNEKKEKRKEAVKKVIAAMTVG--KDVSSLFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSN-YNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR-PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPN------KYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLK-KPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVTAKEVVLSEKP-------LISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP-VGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVP--QVSSMQMGAVDLLGGGLDSLVGQS-------------------------------FIPSSVPATFAPSPTPAVVS------SGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYT---LSLKCRAPEVSQYIYQVYDSILKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62944-1", "uniprot_id": "AP2B1_RAT", "id": "P62944-1", "name": "AP-2 complex subunit beta", "aln": "----------------MTDSKYFTTNK----KGEIFELKAELNNEKKEKRKEAVKKVIAAMTVG--KDVSSLFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSN-YNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR-PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPN------KYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLK-KPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVTAKEVVLSEKP-------LISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP-VGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVP--QVSSMQMGAVDLLGGGLDSLVGQS-------------------------------FIPSSVPATFAPSPTPAVVS------SGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYT---LSLKCRAPEVSQYIYQVYDSILKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBG3-1", "uniprot_id": "AP2B1_MOUSE", "id": "Q9DBG3-1", "name": "AP-2 complex subunit beta", "aln": "----------------MTDSKYFTTNK----KGEIFELKAELNNEKKEKRKEAVKKVIAAMTVG--KDVSSLFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSN-YNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKR-PEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPN------KYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLK-KPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVTAKEVVLSEKP-------LISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP-VGTTTTTNLEQPQVIPSQGDLLGDLLNLDLGPPVNVP--QVSSMQMGAVDLLGGGLDSLVGQS-------------------------------FIPSSVPATFAPSPTPAVVS------SGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYT---LSLKCRAPEVSQYIYQVYDSILKN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35643-1", "uniprot_id": "AP1B1_MOUSE", "id": "O35643-1", "name": "AP-1 complex subunit beta-1", "aln": "----------------MTDSKYFTTTK----KGEIFELKAELNSDKKEKKKEAVKKVIASMTVG--KDVSALFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLAN-YMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYATLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKR-PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKP-------LISEETDLIEPTLLDELICYIGTLASVYHKPPNAFVEGGRGVVHKSLPPRTASSESTESPETAPAGAPAGDQPDVIPAQGDLLGDLLNLDLGPPVSGPPLAASSVQMGAVDLLGGGLDSLIGD----------------------------SNFGAPSASVAAAPAPARLGAPIS------SGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQAGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHVPLSPNQTVEISLPLNTVGSVLKMEPLNNLQVAVKNNIDVFYFSTLYPLHVLFVEDGKMDRQMFLATWKDIANENEAQFQIRDCPLNTEAASNKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSFT---LSLKCRAPEVSQHVYQAYETILKN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52303-1", "uniprot_id": "AP1B1_RAT", "id": "P52303-1", "name": "AP-1 complex subunit beta-1", "aln": "----------------MTDSKYFTTTK----KGEIFELKAELNSDKKEKKKEAVKKVIASMTVG--KDVSALFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANRVAALSEIAESHPSSN-LLDLKAQSINKLLTALNECTEWAQIFILDCLGN-YMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYATLLKKLAPPLVTLLSAEPEPQYVPLRNINLIVQKR-PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLDGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKP-------LISEETDLIEPTLLDELICYIGTLASVYHKPPNAFVEGGRGVVHKSLPPRTASSESTESPEAAPAGAPASDQPDVIPAQGDLLGDLLNLDLGPPVSGPPLAASSVQMGAVDLLGGGLDSLMGDEP---------------------EGIGDSNFGAPPASVAAA-APARLGAPVS------SGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHAPLSPNQTVEISLPLNTVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHVLFVEDGKMDRQMFLATWKDIPNENEAQFQIRDCPLNTEAASSKLQSSNIFTVAKRTVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSFT---LSLKCRAPEVSQHDIQAYETILKN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10567-1", "uniprot_id": "AP1B1_HUMAN", "id": "Q10567-1", "name": "AP-1 complex subunit beta-1", "aln": "----------------MTDSKYFTTTK----KGEIFELKAELNSDKKEKKKEAVKKVIASMTVG--KDVSALFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLAN-YMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKR-PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKP-------LISEETDLIEPTLLDELICYIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPDVIPAQGDLLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLMGDEP---------------------EGIGGTNFVAPPT----AAVPANLGAPIG------SGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHAPLSPNQTVEISLPLSTVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHILFVEDGKMDRQMFLATWKDIPNENEAQFQIRDCPLNAEAASSKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSCTDLELSLKCRAPEVSQHVYQAYETILKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCE3-1", "uniprot_id": "A0A8M2BCE3_DANRE", "id": "A0A8M2BCE3-1", "name": "AP complex subunit beta", "aln": "MEWASQLCENRGLGSKMTDSKYFTTTK----KGEIFELKAELNSDKKEKKKEAVKKVIASMTVG--KDVSALFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPNSN-LLDLNPQTINKLLTALNECTEWGQIFILDCLAN-YTPRDDRESQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLPKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKR-PEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQ---VLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLST--DPVAAKEVVLAEKP-------LISEETDLIEPTLLDELICHIGTLASVYHKPPSAFVEGSRGVQHKRLPARAGSGESAESPEVGQSGTSEAP-PAVIPSQGDLLGDLLNLDLAPATTTVPSVQPSMQMGAMDLLGGGLDSLMGDESDTPGVSHRTEMQSPQPSSDYSERELGGDIGGSPSMGAALGAPAAMPAALSNAPAVGGGLGDLFDLGGGVGMPTGFYVAPKTLFLPAMKAKGLEISGTFARRGGIIQMDLSLTNKAMSVMTDFAIQFNRNSFGLAPAGPLQVLTPLTPNQTIDVSLPLGTTGPVMKMEPLNNLQVAVKNNIDVFYFSCQYPLSLLFVEDGKMERQVFLATWKDIPNDNEAQFQIKDVHLNSDAASNKLQGSNIFTIAKRTVDAQDMLYQSIKLTNGIWVLAEMRVQTGNPNYT---LSIKCRAPEVSQFVYQCYELVLKN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24253-1", "uniprot_id": "Q24253_DROME", "id": "Q24253-1", "name": "AP complex subunit beta", "aln": "----------------MTDSKYFTTTK----KGEIFELKSELNNDKKEKKKEAVKKVIASMTVG--KDVSALFPDVVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDP--YVRKTAAVCVAKLYDISATMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEINEASQSGQPLVEMNSVTINKLLTALNECTEWGQVFILDSLAN-YSPKDEREAQSICERITPRLAHANAAVVLSAVKVLMKLLEMLSSDSDFCATLTKKLAPPLVTLLSSEPEVQYVALRNINLIVQKR-PDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQ---VLSELKEYATEVDVDFVRKAVRAIGRCAIKVEPS--AERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPN------KYESIISTLCENLDTLDEPEARASMVWIIGEYAERIDNADELLDSFLEGFQDENAQVQLQLLTAVVKLFLK-RPSDTQELVQHVLSLATQDSDNPDLRDRGFIYWRLLST--DPAAAKEVVLADKP-------LISEETDLLEPTLLDELICHISSLASVYHKPPTAFVEGRGAGVRKSLPNRAAGSAAGAEQAENAAGS----EAMVIPNQESLIGDLLSMDINAPAMPS----APAATSNVDLLGGGLDILLGGP-------------------------------------PAEAAPGGATSLLG----------DIFGLGG--ATLSVGVQIPKVTWLPAEKGKGLEIQGTFSRRNGEVFMDMTLTNKAMQPMTNFAIQLNKNSFGLVPASPMQA-APLPPNQSIEVSMALGTNGPIQRMEPLNNLQVAVKNNIDIFYFACLVHGNVLFAEDGQLDKRVFLNTWKEIPAANELQYTLSGVIGTTDGIASKMTTNNIFTIAKRNVEGQDMLYQSLKLTNNIWVLLELKLQPGNPEAT---LSLKSRSVEVANIIFAAYEAIIRSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36000-1", "uniprot_id": "AP1B1_YEAST", "id": "P36000-1", "name": "AP-1 complex subunit beta-1", "aln": "-----MPPLDKRIKKFLKDSIRIAPKIS--GKGELSELRTGLVSQYPQTRKDAIKKTIQQMTLG--KDVSSLFPDVLKNIATID-VEQKKLVYLYVMNYAETHPELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNA--YVRKTAVICVAKLFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHVSQFLLALNECTEWARIIILGTLSE-YSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKVIVRNLPQIEYSS--NSLIMKRLSSAFVSLMSTPPEMQYVALKNIRIILEKY-PELLTKELRIFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCTLLLTELKEYAMEYEPEFVSRAIQALSQLGIKYAQESFVSKVLDILLELLE-RQDTIKDDCCISLCDLLRHCPGNDKMAKQVCAVFNTWSNPEVLLQSDIAKCNYVWLLGQHPNNFSDLESKINIFIENFVQEEALTQMSLLMTIVRLHAT-LTG---SMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNNESLVNDLCQNKLP-------MISNTLEKFSPEVLEKLLMELGTISSIYFKPDSNRRKGKKYVQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------IVKGKHIEELESMAKN-----------EISSKANDDVLLDFDERDD--------------VTNTNAGMLNTLTTLGDLDDLFDFGPSEDATQIN----------------------------------TNDTKAVQGLKELKLGGDSNGISSGGKNNPDVSGGNIVSQDLLDLF---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P27351-1", "uniprot_id": "AP2B_YEAST", "id": "P27351-1", "name": "AP-2 complex subunit beta", "aln": "----------------MSDQKVFARYKANEIVTDLQHFGVKKFKSNITRRKNALRKIIANLVLGNYGEMSVLFSELLKFWQIEDDLEVKRICHEYIRVIGALKPQQAREALPFIMDDFKSRDEKLQIMALRTLVLVPVKELSDQAFDCIISLVNHKSPPEQVTRTAIYALLDLDEIDHERVLGLSSILHDIVKAQSSSPEVIVAALHTLYSIHEKN-ANMEPFRIPLELAFDMLELLPELNEWNKATVLEVLTTSVVPQHYLDTHEMIELALPYLQQVNTYVVLNSLKFIMYLLNYVDVIK---ETLAEKLSNSVIALLDKPPELQFLVLRNVILLLLSRESSLLRLDISYFFIEYNDPIYIKDTKLECLYLLANKETLPR---ILEELEQYATDIDIQMSRKSVRAIGNLAVKLDEDS-VHDCVAVLLDLLEFGVDYVVQEIISVFRNILRKYPN------NFKANVTELVKHTEVVQEPESKNAMIWIITQYSDVIPNYLELFRVFSSNMFSETLEVQFSILNSAIKFFIRSPTKETEELCMDLLKGCIDHENNPDLRDKTLMYWRLLSLTKTSRISNAITFESLKSVLDGELPLIEMNTKLDPTVLEELELNIGTIVSIYLKPVSHIFR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LNKTKLLPQS------------------PILNPNKDLLPVVG------------NSFPPTGANRDRQNSESQSSTKSRKTAMMDDYDKPAEKIN------------------------------------------QLKGKRKSSSNNPSKLSRKPSTLLRKLSMKRPFS-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*. :: :: .: .. :*:*::* * :.:* ::* **.:::: : :* *:: : *: . :*: . *: :: * :. : :: :*:**: : *.:: : : ::.... * :** .: .* ::. . : .*.* *:. :* .* : : .:* * * .** : :* * .:. :::.: : . * :.*. *** ::*.:: : : : ::*: ..::*:. ** *:: *:*: ::: . ..:* :: *::::***:*:* *:: : *.. .: : :* **::** : : :: ::::*:.. .:* . . : **:*:: : : :: : :::*: *. : : . : ::. :: :*:: ::.: : : . : * ..: .* .*: :* : :::. . .: :*. . :. .: *:** :*** ** : : . : : :.* :*::* :.:: *:* ** . . * * : . :. .. .* . : . : * : * : . . . : .: ", "identical_positions": 95, "similar_positions": 249, "identity": "9.22%" }, { "cls_id": "homologset.agr.FB:FBgn0010382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P39949-1", "uniprot_id": "CCNE1_RAT", "id": "P39949-1", "name": "G1/S-specific cyclin-E1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRERKERDSK-DHTKMKEEGGSDLSVRSRKRKPNVPVFLQDPDEEIAKIDKTVKSQDSSQP----------------------------WDDDSACVDPCSFIPTPNKEEDN----ELEYPKTAFQPRKIRPP-----------RASPLPVLNWANREEVWRIMLNKEKT--YLRDEHFLQRHPLLQARMRAVLLDWLMEVCEVYKLHRETFYLAQDFFDRYMASQQNIIKTLLQLIGISALFIASKLEEIYPPKLHQFAYVTDGACSGDEILTMELMMMKALKWRLSPLTIVSWLNVYVQVAYVNDTG----------------EVLMPQYPQQVFVQIAELLDLCVLDVGCLEFPYGVLAASALYHFSSLELMQKVSGYQWCDIEKCVKWMVPFAMVIREMGSSKLKHFRG---------------VPMEDSHNIQTHTNSLDLLDKAQAKKAILSEQ---NRISPP----PSG-VLTPPHSSKKQSSEQETE-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61457-1", "uniprot_id": "CCNE1_MOUSE", "id": "Q61457-1", "name": "G1/S-specific cyclin-E1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPR---ERDST-DHSNMKEEGGSDLSVRSRKRKANVAVFLQDPDEEIAKIDKTVKSEDSSQP----------------------------WDDNSACVDPCSFIPTPNKEEDN----ELEYPRTAFQPRKIRPP-----------RASPLPVLNWGNREEVWRIMLNKEKT--YLRDEHFLQRHPLLQARMRAVLLDWLMEVCEVYKLHRETFYLAQDFFDRYMASQHNIIKTLLQLIGISALFIASKLEEIYPPKLHQFAYVTDGACSGDEILTMELMMMKALKWRLSPLTIVSWLNVYVQVAYVNDTG----------------EVLMPQYPQQVFVQIAELLDLCVLDVGCLEFPYGVLAASALYHFSSLELMQKVSGYQWCDIEKCVKWMVPFAMVIREMGSSKLKHFRG---------------VPMEDSHNIQTHTNSLDLLDKAQAKKAILSEQ---NRISPP----PSV-VLTPPPSSKKQSSEQETE-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24864-1", "uniprot_id": "CCNE1_HUMAN", "id": "P24864-1", "name": "G1/S-specific cyclin-E1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRERRERDAK-ERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQP----------------------------WDNNAVCADPCSLIPTPDKEDD-----DRVYPNSTCKPRIIAPS-----------RGSPLPVLSWANREEVWKIMLNKEKT--YLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLH----------------EVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRG---------------VADEDAHNIQTHRDSLDLLDKARAKKAMLSEQ---NRASPL----PSG-LLTPPQSGKKQSSGPEMA-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47794-1", "uniprot_id": "CCNE1_DANRE", "id": "P47794-1", "name": "G1/S-specific cyclin-E1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPS--KKVLQT-EHINTTDEAPKTTSVRPRKRKADVAIHLQDPDEEVTEMTR--KKQCASQAC---------------------------WNPDTGYTSPCRRIPTPDEVEEPVAFGSVGFTQYASESIFITPT-----------RSTPLPALCWASKDEVWNNLLGKDKL--YLRDTRVMERHPNLQPKMRAILLDWLMEVCEVYKLHRETFYLGQDYFDRFMATQENVLKTTLQLIGISCLFIAAKMEEIYPPKVHQFAYVTDGACTEDDILSMEIIIMKELNWSLSPLTPVAWLNIYMQMAYLKETA----------------EVLTAQYPQATFVQIAELLDLCILDVRSLEFSYSLLAASALFHFSSLELVIKVSGLKWCDLEECVRWMVPFAMSIREAGSSALKTFKG---------------IAADDMHNIQTHVPYLEWLGKVHSYQLVDIES---SQRSPV----PTG-VLTPPPSSEKPESTIS---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZQ41-1", "uniprot_id": "D3ZQ41_RAT", "id": "D3ZQ41-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSSRLQAKQQHARPNQPDSPQEAQIIQAKKRKTAQDVKKRTEEITKKHQYEIRNCWPPV-------------------------------LSGGISPCIIIETPHKEIGTS--DFSRFTNYRFKNLFINP--------------SPLPDLSWACSQEVWQNMLQKESR--YVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDIP----------------KVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISECVDWMVPFVSVVKSVSPVKLKTFKK---------------IPMEDRHNIQTHTNYLALLNEVN-YVNIFRKG---GQLSPV----CNGGIMTPPKSTEKPPVKF----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z238-1", "uniprot_id": "CCNE2_MOUSE", "id": "Q9Z238-1", "name": "G1/S-specific cyclin-E2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSSRLQAK-QHAQPNQPDSPQETQIIQAKKRKTAQDVKKRKEEITKKHQYEIRNCWPPV-------------------------------LSGGISPCIIIETPHKEIGTS--DFSRFTNYRFKNLFINP--------------SPLPDLSWACSQEVWQNMLQKENR--YVHDKHFQVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDVP----------------KVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISECVDWMVPFVSVVKSVSPVKLKTFKK---------------IPMEDRHNIQTHTNYLALLNEVN-YVNIYRKG---GQLSPV----CNGGIMTPPKSTEKPPGKH----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96020-1", "uniprot_id": "CCNE2_HUMAN", "id": "O96020-1", "name": "G1/S-specific cyclin-E2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSSRLQAK-QQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPV-------------------------------LSGGISPCIIIETPHKEIGTS--DFSRFTNYRFKNLFINP--------------SPLPDLSWGCSKEVWLNMLKKESR--YVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAP----------------KVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKK---------------IPMEDRHNIQTHTNYLAMLEEVN-YINTFRKG---GQLSPV----CNGGIMTPPKSTEKPPGKH----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54733-1", "uniprot_id": "CCNE_DROME", "id": "P54733-1", "name": "G1/S-specific cyclin-E", "aln": "MGLNAKSVCSTSSTEPNGSIVTTAPSNGEVSSSIVVVVSSSSISSSSDSPIAILPHPDPIPSTSFSSASQRSEEELPGTSAASRTDEMCSCDSQNLAASTAATSNGNKRKRRLSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSSPAEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVVVRYAAEQVVTSTVVTQKTEDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCSGLDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMAQDAAHAMRARIQASPATALRAPESLLTPPASSHKPDEYLGDEGDETGARSGISSTTTCCNTAASNKGGKSSSNNSVTSCSSRSNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . ... :: *::. : . * : . . . * *** * *. :** : ::. ::. . *. *:.:**::*****:******.********. *::**:: ..: *. ******:.**:*:*:****.**: :*********: :** * ::: *.* :.*:* .**.:::*: : .: .*:. *:* ::***** * : :: * :*:*:*: * * *: : ** .* :. *. ** ** : . .. : : :* * **** : :. : ** ::*** * .* ", "identical_positions": 109, "similar_positions": 105, "identity": "15.37%" }, { "cls_id": "homologset.agr.FB:FBgn0010383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51590-1", "uniprot_id": "CP2J3_RAT", "id": "P51590-1", "name": "Cytochrome P450 2J3", "aln": "---------------------MLVTAGSLLGAIWT--------------------VLHLRILLLAAVTFLFLADFLKHRRPKNYPPGPWRLPLVGCLFHLDPKQP--H---------------------LSLQQFV---KKYGNVLSLDFAN-IPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHLF---NKNGLIFSS-GQTWKEQRRFALMTLRNFGL-----GKKSLEQRIQEEAYHLVEAIKDEGGLPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLPGSHQTLFSNWRKLKLFISDIIKNHRRDWDPDE-PRDFIDAFLKEMAKYPDKTT-T-SFNEEN----LICSTLDLFFAGTETTSTTLRWALLCMALYPEVQE------------------KMQAEIDRVIGQGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRESFLPFSM---------GKRACLGEQLARSELFIFITSLIQKFTFKPPV---NEK-LSLQFRMSVTISPVSHRLCAIPRL-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54750-1", "uniprot_id": "CP2J6_MOUSE", "id": "O54750-1", "name": "Cytochrome P450 2J6", "aln": "---------------------MLAATGSLLATIWA--------------------ALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQP--H---------------------LSIQPLV---KKYGNIFSLNLGD-ITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERIS---NKNGLIFSS-GQIWKEQRRFALMTLRNFGL-----GKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDE-PRDFIDAFLKEMTKYPEKTT---SFNEEN----LICSTLDLFFAGTETTSTTLRWALLYMALYPEVQE------------------KVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLE-NGQFKKRESFLPFSM---------GKRACLGEQLARSELFIFFTSLMQKFTFNPPI---NEK-LSPKFRNGLTLSPVSHRICAVPRQ-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51589-1", "uniprot_id": "CP2J2_HUMAN", "id": "P51589-1", "name": "Cytochrome P450 2J2", "aln": "---------------------MLAAMGSLAAALWA--------------------VVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQS--H---------------------LEVQLFV---KKYGNLFSLELGD-ISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIF---KKNGLIMSS-GQAWKEQRRFTLTALRNFGL-----GKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAE-TRDFIDAYLKEMSKHTGNPT-S-SFHEEN----LICSTLDLFFAGTETTSTTLRWALLYMALYPEIQE------------------KVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLE-NGQFKKREAFMPFSI---------GKRACLGEQLARTELFIFFTSLMQKFTFRPPN---NEK-LSLKFRMGITISPVSHRLCAVPQV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JTQ9-1", "uniprot_id": "A0A0G2JTQ9_RAT", "id": "A0A0G2JTQ9-1", "name": "unspecific monooxygenase", "aln": "---------------------MLATVGSLLAKIWS--------------------AINFWTLLLTLLTFLLLADYLKNRRPNNYPPGPWRLPFVGNLFQFDLNISHLH---------------------LRIQQFV---KKYGNLISLDFGN-ISVVVITGLPLIKEALINNEQNFLKRPIVPSRYRVF---KDNGIFFAN-VHKWKEQRRFALTMLKNFGL-----GKKSLEQCIQEEAHHLVEVIGEEKGQPFDPHFRINNAVSNIICSITFGERFEYDDSQFQELLKLADEVICSEASMTSVLYNVFPLIFKYLPGPHQTVFKNWEKLKSIVANMIDRHRKDWNPDE-PRDFVDAFLTEMTKYPDKTT-T-SFNEEN----LIATTLDLFFAGTETTSTTLRWALLYITLNPEVQE------------------KVHSEIDRVIGHGRLPSTDDQDAMPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRDSFLPFSV---------GKRACPGEKLAKSELFIFFTALMQNFTFKAPT---NEK-LSLKLRKGLSLYPVSYRICAVPR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8U1-1", "uniprot_id": "A0A140T8U1_MOUSE", "id": "A0A140T8U1-1", "name": "unspecific monooxygenase", "aln": "---------------------MLSTVGSLVARIWS--------------------AIHLWTLLLTLLVFRLLADYLKNRRPKNYPPGPWRLPFVGNLFQFDLDVSQLH---------------------LRIQLFV---KKYGNLISIDFGN-ISSVVITGLPLIKEAFTDMEQNLLKRPIIPSRKHVF---KDNGIIFSS-GQKWKEQRRFALMILKSFGL-----GKKSLEQRIQEEAYHLVKAMEEEKGQPFDPHFRINSAVSNIICSINFGERFEYGDNKFQELLKITNETLSAETSMMLVLYNALPSIMKYLPGPHQTVFRNWERLKMIVYHMMESHRKDWNPDE-PRDFIDAFLTEMTKYPDKTT-T-SFNEEN----LICSCLDLFIAGTETSSTALRWALLYMTLNPEVQE------------------RVHSEIDGVIGQWRQPSTGDRDSMPYTNAVIHEVLRMGNIVPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDIFNPEHFLE-NGQFKKRESFLPFSM---------GKRACPGEQLARTELFIFFTALMQKFTFKAPV---NEK-LSLKFRMSVPISPVSYCICAVPRQ-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UZ38-1", "uniprot_id": "G3UZ38_MOUSE", "id": "G3UZ38-1", "name": "unspecific monooxygenase", "aln": "---------------------MFATIGCLVSNICS--------------------EIHLWTLLLAALTLLLLVDYIKNRHPKNYPPGPWRLPFVGNLFQFDLDVSHLH---------------------LGIQPFV---KKYGNLISLDFGT-IPSVIISGEPLIKEALTCMGQNFLKRPILAARQHIF---KNNGIISSS-GQTWKEQRRFTLMILKNFGL-----GKKSLEQRIQDEAHHLVEAIAEEKGRPFDPHFMINNAVSNIICSITIGERFEYEDNQFQELLKLADETLCLEASKVLMLYNVFPSIFKYLPGPHQKLFSNWEKLKLFFSHVMDSHRKDWNPSA-PRDFIDAFLTEMAKYSDKTT-T-SFNEEN----LICTTLDLFFAGTETTSTALRWALLYITVNPEVQE------------------KVHSEIDRVIGQGRHPTIDDRDSMPYTNAVIHEVLRMGNIIPLNVPREVEADITLAGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLE-NGQFKKRESFLPFSV---------GKRGCPGEQLARSELFTFFTALMQKFTFKPPI---NEK-LSLNFKMGVALSPVSYCICAVPR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UXT0-1", "uniprot_id": "G3UXT0_MOUSE", "id": "G3UXT0-1", "name": "unspecific monooxygenase", "aln": "---------------------MLATEDTFETAIWA--------------------LLHFKTLVLAAVTFMLLAHYLKTQRPKNYPPGPWRLPFVGNLFQLDLEQP--H---------------------VVIQQFV---KKYGNLTSLDFGN-IPSVIITGLPLIKEVFTNMEQNFLNRPITPIRKRVF---NNNGLIISN-GQTWKEQRRFALMTLKNFGL-----GKKSLEQRIQKEADCLVEAIGEEKGQPFDPHFKINSAVSNIICTFAFGERFEYEDSHFHELLRLLDEATCLEASMMCQLYNVFPSIIQYVPGSHQTVLRNWEKLKLFIYQMMESHRKDWNPDE-PRDFIDAFLTEMSKYGDKTT-T-SFNEEN----LINSTLDLFFAGSETTTNTLRWALLYITTNPEVQE------------------KVHSEIDRVIGHGRQPSTDDRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHFLE-NGQFKKRESFLPFSL---------GKRACPGEQLARSELFIFFTALMQKFTFKPPI---NEK-LSLKFRNGLTLSPVSHCICAVPRH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54749-1", "uniprot_id": "CP2J5_MOUSE", "id": "O54749-1", "name": "Cytochrome P450 2J5", "aln": "---------------------MIMFLSSLVTTFWE--------------------ALHLKTLVLAVVTFLFLINILRSRHPKNYPPGPWRLPFVGNFFQIDTKQT--H---------------------LVLQQFV---KKYGNVFSLELGQ-SPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERIT---GKNGLVVSN-GQTWKEQRRLALMALRNFGL-----GKKSLEERIQEETHHLVEAIREEGGQPFNPHLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSAGQLYNGFPCIMKYLPGPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDE-PRDFIDAFLIEMQKDPDRTT---SFNEEN----LISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQE------------------NVQAEIDRVIGHKRQVSLSDRESMPYTNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVFNPEHFLE-NGQFKKRESFLPFSM---------GKRACLGEQLAKSELFIFFSALMQKFTFKPPI---NEK-LSLKFRMGLILSPASYRICAIPRV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ56-1", "uniprot_id": "A0A8M1PZ56_DANRE", "id": "A0A8M1PZ56-1", "name": "", "aln": "---------------------------MDMLHFYE--------------------WIDIKSILIFVCVFLLLSDFIKNKTPKNFPPGPWSLPIIGDIHHIDPSKL--H---------------------LQLSEFA---EKYGKIFSLRLFG-PRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDII---GDKGLVASS-GYKWKQQRRFALSTLRNFGL-----GKKNLEPSINLESGFLNEAISNEQGQPFDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMRLLPGPHKRIIALWGKLIEFVGEKVNEHKVDHDPLN-PRDYIDCFLDEMEKHKDDTA-A-GFDVEN----LCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQA------------------KVQQEIDVIVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEKYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSL---------GKRVCLGEQLARMELFLFFSSLLQRFTFSPPA---GVE-PSLDYNLGATHCPQPYKLCAVPH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TES7-1", "uniprot_id": "A0AB32TES7_DANRE", "id": "A0AB32TES7-1", "name": "", "aln": "------------------------MSSVFSQLIGQ--------------------WLDVQGFLIFLCVLLLVKHFR-DVYSKNMPPGPFPLPFVGNLTNIGFSDP--L---------------------GSFQRIA---EKYGDVCTLYLGT-KPCILMTGYETLKEAFVEQADIFTDRPYFPIVDKLG---NGKGLIMSS-GHMWRQQRRFALATLKYFGV-----GKKTLENAILQECRFLCDSLQAERGLPFDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGRLYNEFPTLMSLLPGKHQTAFASMSKLQPFLKEEIIKHQQDREPSS-PRDYIDCYLEEIEKCK-DSD-A-EFTEEN----LMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQE------------------KVQSEIDQVIGQTRQPLMDDRTNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPKGVIVLPMLKPILLDKKEYSTPYDFNPAHFLDQNGKFLKKENFIPFSI---------GKRMCPGEQLARMELFLFFISLMQHFTFLPVE---GQK-LSLKGTTSVSSAPQPFQIRAVPR------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N004-1", "uniprot_id": "A0A8M1N004_DANRE", "id": "A0A8M1N004-1", "name": "", "aln": "------------------------MFGALVKLDLS--------------------SVG-LTLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHL-LRDP------------------------MGFNRLM---AQYGEMSTMYLGK-KPAIVLNTIQVAKEALVQ--EAFAGRPCLPVIDWTS---NGCGIIMATFNNSWKQQRRFALHTLRNFGL-----GKKSIESRVLEESQYLFAELLKDEGEPVNPHHALQNAVSNIFCSIMFGERFDYDNKRLGYLLKILNENMMLTGSAIGQIFNLAP-FIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVS-PRDFIDAYLLEIEKQKSNKD-S-TFQEEN----LIGSAIDLFFAGTDSTATSIRWGLLFLIQNPDVQE------------------RCHEEIVQVLGYDRLPCMDDCDRLPYTHATVHEIQRFAKTVPFGVFHETIWPTKLHGFDIPQGTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESYIPFSL---------GLRACIGESLVRTELFLFATVLLQRIHFSWPP---DAKPLDMDGIVGIVRYPQTFSIICCSRDSKK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IQ46-1", "uniprot_id": "A0A0R4IQ46_DANRE", "id": "A0A0R4IQ46-1", "name": "", "aln": "------------------------MFASLLKLDLA--------------------SVG-LTLFLGLIFLVVFEIFRIRSYSGRFPPGPTPLPFVGTIPHF-LKDS------------------------MGFIRSL---SQYGEMTTVYLGR-KPAMVLNTLQVIKEAIVQNGTSSSGRPSIPILTWIT---EGYGIVLATFGHSWRQQRRFALHTLRNFGL-----GKKSVEERVTEESGYLVPEMLKLEGKPFDPQHAIQNAVSNIICSIVFGDRFEYDNKRFEYLLEIIKENINQAGSLIGQVFNLIP-IIKHFPGPHQKIYQNAEELKSFIRESTKSHRETLDPDS-PRDFIDAYLLEMEKQKSSQD-S-SFHEDN----MVMSVADLFLAGSDTTATTIRWGLIYLTQNPDVQE------------------RCHEEIVRVLGYDRLPCMDDRDRLPYTLATVHELQRCGNIVPSSVPHETTQPMKLRGYDIPQGTQMLINLSDILANKEHWKHPDTFNPENFLDDKGHFYRPEAFLPFSL---------GPRVCLGETLAKTELFLFITSLLQRIRFSWPT---GEKWPNMDGIVSVVRSPEPFKIICHSRGSKE--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F7FAJ1-1", "uniprot_id": "F7FAJ1_RAT", "id": "F7FAJ1-1", "name": "Vitamin D 25-hydroxylase", "aln": "MGVRQGWKARPGLSETNWFPPQPWPMFQLPGVQTCAG-------------------ALAGAFLLL-LLVLVVRQLLRQRRPAGFPPGPPRLPFIGNICSLALSADLP---------------------HVYMRKQS---RVFGEIFSLDLGG-ISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKM---TKMGGLLNSRYGRGWIDHRRLAVNSFHYFGS-----GQKSFESKILEETWSLIDAIETYKGRPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSKLIEKAAVNRKPHL-PQNFVDAYLDEMDKGQNDPL-S-TFSKEN----LIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQG------------------QVHKEIDLIMGHDRRPSWEDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSSGYFTKKEALIPFSL---------GRRHCLGEQLARMEMFLFFTSLLQQFHLHFP----HELVPNLKPRLGMTLQPQAYLICAERR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VVW9-1", "uniprot_id": "CP2R1_MOUSE", "id": "Q6VVW9-1", "name": "Vitamin D 25-hydroxylase", "aln": "-------------------------MLELPGARACAG-------------------ALAGALLLL-LFVLVVRQLLRQRRPAGFPPGPPRLPFVGNICSLALSADLP---------------------HVYMRKQS---RVYGEIFSLDLGG-ISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKM---TKMGGLLNSRYGRGWIDHRRLAVNSFHYFGS-----GQKSFESKILEETWSLIDAIETYKGGPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSRLIEKAAVNRKPHL-PHHFVDAYLDEMDQGQNDPL-S-TFSKEN----LIFSVGELIIAGTETTTNVLRWAILFMALYPNIQG------------------QVHKEIDLIVGHNRRPSWEYKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSNGYFTKKEALIPFSL---------GRRHCLGEQLARMEMFLFFTSLLQQFHLHFP----HELVPNLKPRLGMTLQPQPYLICAERR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VVX0-1", "uniprot_id": "CP2R1_HUMAN", "id": "Q6VVX0-1", "name": "Vitamin D 25-hydroxylase", "aln": "-------------------------MWKLWRAEEGAA-------------------ALGGALFLL-LFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELP---------------------HVYMRKQS---QVYGEIFSLDLGG-ISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKM---TKMGGLLNSRYGRGWVDHRRLAVNSFRYFGY-----GQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQL-PQHFVDAYLDEMDQGKNDPS-S-TFSKEN----LIFSVGELIIAGTETTTNVLRWAILFMALYPNIQG------------------QVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSL---------GRRHCLGEHLARMEMFLFFTALLQRFHLHFP----HELVPDLKPRLGMTLQPQPYLICAERR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CX98-1", "uniprot_id": "CP2U1_MOUSE", "id": "Q9CX98-1", "name": "Cytochrome P450 2U1", "aln": "-------------------------MSSLGDQRPAAGEQPGAR---------LHVRATGGALLLCLLAVLLGWVWLRRQRACGIPPGPKPRPLVGNFGHLLVPRFLRPQFWLGS-----GSQTDTVGQHVYLARMA---RVYGNIFSFFIGH-RLVVVLSDFHSVREALVQQAEVFSDRPRMPLISIM---TKEKGIVFAHYGPIWKQQRRFSHSTLRHFGL-----GKLSLEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINICPWFYYLPFGPFKELRQIERDISCFLKNIIREHQESLDASN-PQDFIDMYLLHMEEEQGASRRS-SFDEDY----LFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQK------------------KVHEEIERVIGCDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKRETFIPFGI---------GKRVCMGEQLAKMELFLMFVSLMQTFTFALPE---GSEKPVMTGRFGLTLAPHPFNVTISKR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8D1-1", "uniprot_id": "CP2U1_RAT", "id": "Q4V8D1-1", "name": "Cytochrome P450 2U1", "aln": "-------------------------MSSIGGLRPAAGEQPGVG---------PHLQAVGGALLLCGLAVLLDWVWLQRQRAGGIPPGPKPRPLVGNFGYLLLPRFLRLHFWLGS-----GSQTDTVGRHVYLARLA---RVYGNIFSFFIGH-RLVVVLSDFQSVREALVQQAEVFSDRPRMPLISIL---TKEKGIVFAHYGPIWKQQRRFSHSTLRHFGL-----GKLSLEPRIIEEFAYVKAEMQKHGEAPFSPFPVISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINLCPWFYYLPFGPFKELRQIERDITCFLKNIIKEHQESLDANN-PQDFIDMYLLHTQEEKDKCKGT-NFDEDY----LFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPGVQK------------------KVHEEIERVIGRDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEKPDDFCPHRFLDDQGQLLKRETFIPFGI---------GKRVCMGEQLAKMELFLMFVSLMQSFTFALPE---GSEKPIMTGRFGLTLAPHPFNVTVSKR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z449-1", "uniprot_id": "CP2U1_HUMAN", "id": "Q7Z449-1", "name": "Cytochrome P450 2U1", "aln": "-------------------------MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA---RVYGSIFSFFIGH-YLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIV---TKEKGVVFAHYGPVWRQQRKFSHSTLRHFGL-----GKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDREN-PQDFIDMYLLHMEEERKNNSNS-SFDEEY----LFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQE------------------KVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGI---------GKRVCMGEQLAKMELFLMFVSLMQSFAFALPE---DSKKPLLTGRFGLTLAPHPFNITISRR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087X1C5-1", "uniprot_id": "CP2D7_HUMAN", "id": "A0A087X1C5-1", "name": "Cytochrome P450 2D7", "aln": "-------------------------MGLEA--------------------------LVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYC-----------------------FDQLR---RRFGDVFSLQLAW-TPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGL-----GKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLPHIP-ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGSPE-S-SFNDEN----LRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSA---------GRRACLGEPLARMELFLFFTSLLQHFSFSVAA---GQPRPSHSRVVSFLVTPSPYELCAVPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10635-1", "uniprot_id": "CP2D6_HUMAN", "id": "P10635-1", "name": "Cytochrome P450 2D6", "aln": "-------------------------MGLEA--------------------------LVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYC-----------------------FDQLR---RRFGDVFSLQLAW-TPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGL-----GKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIP-ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPE-S-SFNDEN----LRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR------------------RVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA---------GRRACLGEPLARMELFLFFTSLLQHFSFSVPT---GQPRPSHHGVFAFLVSPSPYELCAVPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64680-1", "uniprot_id": "CP2D4_RAT", "id": "Q64680-1", "name": "Cytochrome P450 2D4", "aln": "-------------------------MRMPTGSE-----------------------LWPIAIFTIIFLLLVDLMHRRQRWTSRYPPGPVPWPVLGNLLQIDFQNMPAG-----------------------FQKLR---CRFGDLFSLQLAF-ESVVVLNGLPALREALVKYSEDTADRPPLHFNDQSGFGPRSQGVVLARYGPAWRQQRRFSVSTFRHFGL-----GKKSLEQWVTEEARCLCAAFADHSGFPFSPNTLLDKAVCNVIASLLFACRFEYNDPRFIRLLDLLKDTLEEESGFLPMLLNVFPMLLHIP-GLLGKVFSGKKAFVAMLDELLTEHKVTWDPAQPPRDLTDAFLAEVEKAKGNPE-S-SFNDEN----LRVVVADLFMAGMVTTSTTLTWALLFMILRPDVQC------------------RVQQEIDEVIGQVRRPEMADQARMPFTNAVIHEVQRFADILPLGVPHKTSRDIEVQGFLIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQRFSFSVPA---GQPRPSNYGVFGALTTPRPYQLCASPR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10633-1", "uniprot_id": "CP2D1_RAT", "id": "P10633-1", "name": "Cytochrome P450 2D1", "aln": "-------------------------MELLNGTG-----------------------LWSMAIFTVIFILLVDLMHRRHRWTSRYPPGPVPWPVLGNLLQVDLSNMPYS-----------------------LYKLQ---HRYGDVFSLQKGW-KPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGM-----GKKSLEEWVTKEAGHLCDAFTAQAGQSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMVKLVEESLTEVSGFIPEVLNTFPALLRIP-GLADKVFQGQKTFMALLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPE-S-SFNDEN----LRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQR------------------RVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPHRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQRFSFSVPV---GQPRPSTHGFFAFPVAPLPYQLCAVVREQGL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12939-1", "uniprot_id": "CP2DA_RAT", "id": "P12939-1", "name": "Cytochrome P450 2D10", "aln": "-------------------------MELLNGTG-----------------------LWPMAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDPSNMPYS-----------------------MYKLQ---HRYGDVFSLQMGW-KPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVVFASYGPEWREQRRFSVSTLRTFGM-----GKKSLEEWVTKEAGHLCDAFTAQNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVSGFIPEVLNTFPALLRIP-GLADKVFQGQKTFMAFLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPE-S-SFNDEN----LRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQR------------------RVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQHFSFSVPA---GQPRPSTLGNFAISVAPLPYQLCAAVREQGH--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24456-1", "uniprot_id": "CP2DA_MOUSE", "id": "P24456-1", "name": "Cytochrome P450 2D10", "aln": "-------------------------MELLTGAG-----------------------LWSVAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYS-----------------------LYKLQ---NRYGDVFSLQMGW-KPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGL-----GKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIPEVLNMFPILLRIP-GLPGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGNAE-S-SFNDEN----LRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQR------------------RVQQEIDAVIGQVRHPEMADQARMPYTNAVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSA---------GRRSCLGEPLARMELFLFFTCLLQHFSFSVPN---GQPRPRNLGVFPFPVAPYPYQLCAVMREQGH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24457-1", "uniprot_id": "CP2DB_MOUSE", "id": "P24457-1", "name": "Cytochrome P450 2D11", "aln": "-------------------------MELLTGAG-----------------------LWSVAIFTVIFILLVDLMHRHQHWTSRCPPGPVPWPVLGNLLQVDLGNMPYS-----------------------LYKLQ---NRYGDVFSLQMGW-KPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGL-----GKKSLEDWVTKEARHLCDAFTAQAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTEISGFIPGVLNEFPIFLRIP-GLADMVFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTDAFLAEIEKAKGNPE-S-SFNDEN----LRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQR------------------RVQQEIDAVIGQVQHPEMADQARMPYTNAVIHEVQRFGDIAPLPLPRITSRDIEVQDFLVTKGSTLIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSA---------GHRSCLGEALARMELFLFFTCLLQRFSISVPD---GQPQPSNYRVHAIPVAPFPYQLCAVMREQGH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N463-1", "uniprot_id": "L7N463_MOUSE", "id": "L7N463-1", "name": "Cytochrome P450", "aln": "-------------------------MELLTGTG-----------------------LWSVAIFTVIFLILVDLMHRRQHWTSRYPPGPVPWPVLGNLLQVDLDNIPYS-----------------------LYKLQ---NRYGDVFSLQMAW-KPVVVINGLKAMQEVLLTCGKDTADHPPVPIFEYLGFKSKSQGVVLASYGPEWREQRQFSVSTLRNFGL-----GKKSLEEWVTKEAKHLCDAFTARAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPFLIRMLKMREESLKEVTGFIPGVLNTFPILLRIP-GLADMVFQSQKTFMAILDNLVTENRTTWDPDQPPRNLADAFLAEIQKAKGNPE-S-SFNDEN----LCMVVSDLFTAGMVTTSTTLSCALLLMILHPDVQR------------------RVQQEIDAVIGQVRCPEMADQARMPYTNAVIHEVQRFGDIIPLNIPRITSRDIEVQDFLIPKGTILIPNMSSMLKDETVWEKPLRFYPEHFLDAQGHFVKPEAFMPFSA---------GRRSCLGEPLARMELFLFFTCLLQRFSFSVPA---GQPQPSDHRIFAIPVAPYPYQVCAIMREQGH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11714-1", "uniprot_id": "CP2D9_MOUSE", "id": "P11714-1", "name": "Cytochrome P450 2D9", "aln": "-------------------------MELLTGTD-----------------------LWPVAIFTVIFILLVDLTHQRQRWTSRYPPGPVPWPVLGNLLQVDLGNMPYS-----------------------LYKLQ---NRYGDVFSLQMAW-KPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGL-----GKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIP-RLADKALQGQKSFIAILDNLLTENRTTWDPVQAPRNLTDAFLAEIEKAKGNPE-S-SFNDEN----LLMVVRDLFGAGMLTTSTTLSWALMLMILHPDVQR------------------RVQQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPVNLPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSA---------GRRSCLGEALARMELFLFFTCLLQRFSFSVPD---GQPQPSNSGVYGILVAPSPYQLCAVVRDQGH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12938-1", "uniprot_id": "CP2D3_RAT", "id": "P12938-1", "name": "Cytochrome P450 2D3", "aln": "-------------------------MELLAGTG-----------------------LWPMAIFTVIFILLVDLMHRRQRWTSRYPPGPVPWPVLGNLLQVDLCNMPYS-----------------------MYKLQ---NRYGDVFSLQMGW-KPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEWREQRRFSVSTLRNFGV-----GKKSLEQWVTDEASHLCDALTAEAGRPLDPYTLLNKAVCNVIASLIYARRFDYGDPDFIKVLKILKESMGEQTGLFPEVLNMFPVLLRIP-GLADKVFPGQKTFLTMVDNLVTEHKKTWDPDQPPRDLTDAFLAEIEKAKGNPE-S-SFNDAN----LRLVVNDLFGAGMVTTSITLTWALLLMILHPDVQC------------------RVQQEIDEVIGQVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQRFSFSVPT---GQPRPSDYGVFAFLLSPSPYQLCAFKR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10634-1", "uniprot_id": "CP2DQ_RAT", "id": "P10634-1", "name": "Cytochrome P450 2D26", "aln": "-------------------------MGLLIGDD-----------------------LWAVVIFTAIFLLLVDLVHRHKFWTAHYPPGPVPLPGLGNLLQVDFENMPYS-----------------------LYKLR---SRYGDVFSLQIAW-KPVVVINGLKAVRELLVTYGEDTADRPLLPIYNHLGYGNKSKGVVLAPYGPEWREQRRFSVSTLRDFGV-----GKKSLEQWVTEEAGHLCDTFAKEAEHPFNPSILLSKAVSNVIASLVYARRFEYEDPFFNRMLKTLKESFGEDTGFMAEVLNAIPILLQIP-GLPGKVFPKLNSFIALVDKMLIEHKKSWDPAQPPRDMTDAFLAEMQKAKGNPE-S-SFNDEN----LRLVVIDLFMAGMVTTSTTLSWALLLMILHPDVQR------------------RVHEEIDEVIGQVRRPEMADQARMPFTNAVIHEVQRFADIVPTNIPHMTSRDIKFQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSA---------GRRACLGEPLARMELFLFFTCLLQRFSFSVLA---GRPRPSTHGVYALPVTPQPYQLCAVAR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIM7-1", "uniprot_id": "CP2DQ_MOUSE", "id": "Q8CIM7-1", "name": "Cytochrome P450 2D26", "aln": "-------------------------MGLLVGDD-----------------------LWAVVIFTAIFLLLVDLVHRRQRWTACYPPGPVPFPGLGNLLQVDFENIPYS-----------------------FYKLQ---NRYGNVFSLQMAW-KPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSKGVILAPYGPEWREQRRFSVSTLRDFGL-----GKKSLEQWVTEEAGHLCDAFTKEAEHPFNPSPLLSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIP-GLPDKAFPKLNSFIALVNKMLIEHDLTWDPAQPPRDLTDAFLAEVEKAKGNPE-S-SFNDKN----LRIVVIDLFMAGMVTTSTTLSWALLLMILHPDVQR------------------RVHQEIDEVIGHVRHPEMADQARMPYTNAVIHEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYPEHFLDAQGHFVKHEAFMPFSA---------GRRSCLGEPLARMELFLFFTCLLQRFSFSVPD---GQPRPSDYGIYTMPVTPEPYQLCAVAR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35293-1", "uniprot_id": "CP2F2_RAT", "id": "O35293-1", "name": "Cytochrome P450 2F2", "aln": "--------------------------MDGVSTAIL-----------------------LLLLAVISLS---LTFTSWGKGQ--LPPGPKPLPILGNLLQLRSQDLLTS-----------------------LTKLS---KDYGSVFTVYLGP-RRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFT---KGNGIAFSD-GERWKILRRFSVQILRNFGM-----GKRSIEERILEEGSFLLDVLRKTEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHFINDNFQIMSSPWGEMYNIFPSLLDWVPGPHRRVFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMVQEKQDPLSH--FNMDT----LLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQA------------------RVQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDANQSFKKSPAFMPFSA---------GRRLCLGEPLARMELFIYLTSILQNFTLHPL--VEPEDIDLTPLSSGLGNLPRPFQLCMRIR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33267-1", "uniprot_id": "CP2F2_MOUSE", "id": "P33267-1", "name": "Cytochrome P450 2F2", "aln": "--------------------------MDGVSTAIL-----------------------LLLLAVISLS---LTFSSRGKGQ--LPPGPKPLPILGNLLQLRSQDLLTS-----------------------LTKLS---KEYGSVFTVYLGS-RPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFT---RGNGIAFSD-GERWKILRRFSVQILRNFGM-----GKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMAQEKQDPLSH--FNMDT----LLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQA------------------RVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSFKKSPAFMPFSA---------GRRLCLGEPLARMELFIYFTSILQNFTLQPL--VDPEDIDLTPLSSGLGNLPRPFQLCMHIR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K2P4-1", "uniprot_id": "A0A0G2K2P4_RAT", "id": "A0A0G2K2P4-1", "name": "unspecific monooxygenase", "aln": "-------------------------MVTCEATLLL-----------------------LLILTLMLMSWGWLAHQARARMQKDLPPGPAPLPLLGNLLQLQSGHLDRV-----------------------LMELS---SRWGPVFTVWLGP-RPAVVLSGYAALRDALVLQADAFSGRGSMAVFERFT---HGNGIVFSN-GPRWRTLRNFALGALKEFGV-----GTSTIEERILEETACVLDEFQATMGAPFDPRRLLDNAVSNVICTVVFGKRYNYGDPEFLRLLDLFSDNFRIMSSRWGETYNMFPSFMDWIPGPHHRIFKNFQELRLFISEQIQWHRQSRQTGEP-RDFIDCFLEQMDKEHQDPESH--FQDET----LVMTTHNLFFGGTETTSTTLRYGLLIMLKYPEVAA------------------KVQEELDATVGRTRAPSLADRAHLPYTNAVLHEIQRFISVLPLGLPRALIRDVNLRNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDQGEFQNNDAFMPFAP---------GKRMCLGAGLARSEIFLFLTAILQKFSLLPV--GSPADIDLTPQCTGLGNVPPAFQLRLVAR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12791-1", "uniprot_id": "CP2BA_MOUSE", "id": "P12791-1", "name": "Cytochrome P450 2B10", "aln": "----------------------------MEPSVLL-----------------------LLALLVGF--LLLLAR-GHPKSRGNFPPGPRPLPLLGNLLQMDRGGLLKS-----------------------LIQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTF---KEYGVIFAN-GERWKTLRRFSLATMRDFGM-----GKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANVICSIVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLKYFPGAHRQISKNLQELLDYIGHSVERHKATLDPSVP-RDFIDIYLLRMEKEKSNQNAE--FHHQN----LMMSVLSLFFVGTETSSTTLHYGFLLMLKYPHVTE------------------KVQKEIDQVIGSHRLPTLDDRTKMPYSDAVIHEIQRFSDLIPIGVPHRVTKDTLFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDQFLDANGALKKSEAFLPFSTGQIFDQKSVGKRICLGESIARSELFLFFTSILQNFSVASH--VAPKDIDLTPKESGIGKIPPTYQICFLAR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04167-1", "uniprot_id": "CP2B2_RAT", "id": "P04167-1", "name": "Cytochrome P450 2B2", "aln": "----------------------------MEPSILL-----------------------LLALLVGF--LLLLVR-GHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNS-----------------------FMQLR---EKYGDVFTVHLGP-RPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIF---KEYGVIFAN-GERWKALRRFSLATMRDFGM-----GKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAP-RDFIDTYLLRMEKEKSNHHTE--FHHEN----LMISLLSLFFAGTETGSTTLRYGFLLMLKYPHVTE------------------KVQKEIDQVIGSHRPPSLDDRTKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDTFNPEHFLDADGTLKKSEAFMPFST---------GKRICLGEGIARNELFLFFTTILQNFSVSSH--LAPKDIDLTPKESGIAKIPPTYQICFSAR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q593-1", "uniprot_id": "E9Q593_MOUSE", "id": "E9Q593-1", "name": "Cytochrome P450", "aln": "----------------------------MEPSVLL-----------------------LLALLTGF--LLLLIR-GQPKAYSRLPPGPRPLPFLGNLLQMDRGGLLKS-----------------------FIKLR---DKHGDVFTVHLGP-RPVVMLYGTETIKEALVDHSDAFSGRGAIAVIQPIV---QDYGVIFSS-GERWKTLRRFSLATMRDFGM-----GKRSVEERIKEEAQCLVEELKKYEGAPLDPTFLFQCITANIICSIVFGERFDYTDHQFLHLLDLFYQTLSLISSFSSQLFELFSAVLKYFPGTHRQISKNIQEILNYIGHSVEQHKATLDPSAP-RDFIDTYLLRMEKEKSNHHTE--FHHQN----LLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAE------------------KVQKEIDQVISAHHVPTLEDRIKMPYTEAVIHEIQRFSDLAPIGLPHTVTKDTVFRGYLLPKNTEVYPILSSALHDPQYFEQPDKFNPEHFLDANGALKKSEAFLPFST---------GKRICLGEGIARNELFLFFTALLQNFSLSSP--VAPEDIDLTPKESGFVKIPPVYRICFLPR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZZ08-1", "uniprot_id": "A0A8I5ZZ08_RAT", "id": "A0A8I5ZZ08-1", "name": "Cytochrome P450", "aln": "----------------------------MEPSVLL-----------------------LLAVLLSF--LLLLVR-GHAKIHGRLPPGPCPVPLLGNLLQMDRRGLLKS-----------------------FIQLRPIWEKYGDVFTVHLGL-RPVVVLCGTQTIREALVDHAEAFSGRGTIAGLEPVF---QDYGIFFSS-GEQWKTLRRFSMATMRDFGM-----RKKSVEERIKEESQCLVEELKKYQGAPLDPTFLFQCITSNIICSIVFGECFDYTDHQFLHLLDLMYQTFSLLSSIFSQVFELFPGVLKYFPGAHRQISRNLHEILDFIGQSVEKHRATLDPNAP-RDFIYTYLLHMEK-KSNHYTE--FHHWN----LLSSVLSLFFAGTETSSTTLRYGFLIMLKYPHITE------------------KVQKEIDCVIGSHRLPTLDDRSKMPYTEAVIHEIQRFSDLAPIGTPHRVIKDTIFRGYLLPKNTEVFPILSSVLHDPQYFEQPDIFNLQHFLDANGALKIIEAFLPFST---------GKRICLGESIARNELFLFFTTILQNFSVSSP--VAPKDIDLTPKESGIGRIPQVYQICFLAH------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12790-1", "uniprot_id": "CP2B9_MOUSE", "id": "P12790-1", "name": "Cytochrome P450 2B9", "aln": "----------------------------MDPSVLL-----------------------LLAVLLSL--FLLLVR-GHAKIHGHLPPGPHPLPLLGNLLQMDRGGLLKC-----------------------FIQLQ---EKHGDVFTVHLGP-RPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVM---QDYGIFFAS-GQRWKTLRRFSLATMKEFGM-----GKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLDPSAP-RDYIDTYLLRMEKEKSNHNTE--FHHQN----LMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTE------------------KVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLDANGALKKCEAFLPFST---------GKRICLGESIARNELFIFFTTILQNFSVASP--VAPKDIDLTPKESGIGKIPPAHQIYFLAR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33272-1", "uniprot_id": "CP2BC_RAT", "id": "P33272-1", "name": "Cytochrome P450 2B12", "aln": "----------------------------MEFGVLL-----------------------LLTLTVGF--LLFLVSQSQPKTHGHLPPGPRPLPFLGNLLQMNRRGFLNS-----------------------FMQLQ---EKYGDVFTVHLGP-RPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVV---QGYGVIFAT-GERWKTLRRFSLVTMKEFGM-----GKRSVDERIKEEAQCLVEELKKYKGAPLNPTFLFQSIAANTICSIVFGERFDYKDHQFLHLLDLVYKTSVLMGSLSSQVFELYSGFLKYFPGAHKQIFKNLQEMLNYIGHIVEKHRATLDPSAP-RDFIDTYLLRMEKEKSNHHTE--FNHQN----LVISVLSLFFAGTETTSTTLRCTFLIMLKYPHVAE------------------KVQKEIDQVIGSHRLPTPDDRTKMPYTDAVIHEIQRFADLTPIGLPHRVTKDTVFRGYLLPKNTEVYPILSSALHDPRYFEQPDTFNPEHFLDANGALKKSEAFLPFST---------GKRICLGEGIARNELFIFFTAILQNFTLASP--VAPEDIDLTPINIGVGKIPSPYQINFLSR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LT33-1", "uniprot_id": "F1LT33_RAT", "id": "F1LT33-1", "name": "Cytochrome P450", "aln": "----------------------------MELGVFL-----------------------LLTFTVGF--LLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRS-----------------------FMQLQ---EKYGDVFTVHLGP-RPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVV---QGYGVIFAN-GERWKILRRFSLVTMRNFGM-----GKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTP-RDFIDTYLLHMEKEKSNHHTE--FHHQN----LVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAE------------------KVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFST---------GKRTCLGEGIARNELFIFFTALLQNFSLASP--VAPEDIDLTPINSGAGKIPSPYQINFLSRCVG---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20813-1", "uniprot_id": "CP2B6_HUMAN", "id": "P20813-1", "name": "Cytochrome P450 2B6", "aln": "----------------------------MELSVLL-----------------------FLALLTGL--LLLLVQ-RHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKS-----------------------FLRFR---EKYGDVFTVHLGP-RPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFF---RGYGVIFAN-GNRWKVLRRFSVTTMRDFGM-----GKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAP-KDLIDTYLLHMEKEKSNAHSE--FSHQN----LNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAE------------------RVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSL---------GKRICLGEGIARAELFLFFTTILQNFSMASP--VAPEDIDLTPQECGVGKIPPTYQIRFLPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11509-1", "uniprot_id": "CP2A6_HUMAN", "id": "P11509-1", "name": "Cytochrome P450 2A6", "aln": "----------------------------MLASGML-----------------------LVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNS-----------------------LMKIS---ERYGPVFTIHLGP-RRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVF---KGYGVVFSN-GERAKQLRRFSIATLRDFGV-----GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSP-RDFIDSFLIRMQEEEKNPNTE--FYLKN----LVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEA------------------KVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSI---------GKRNCFGEGLARMELFLFFTTVMQNFRLKSS--QSPKDIDVSPKHVGFATIPRNYTMSFLPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20853-1", "uniprot_id": "CP2A7_HUMAN", "id": "P20853-1", "name": "Cytochrome P450 2A7", "aln": "----------------------------MLASGLL-----------------------LVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDS-----------------------IMKFS---ECYGPVFTIHLGP-RRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVF---KGYGVAFSN-GERAKQLLRFAIATLRDFGV-----GKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSP-QDFIDSFLIHMQEEEKNPNTE--FYLKN----LMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEA------------------KVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSI---------GKRNCFGEGLARMELFLFFTTVMQNFRLKSS--QSPKDIDVSPKHVVFATIPRNYTMSFLPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q16696-1", "uniprot_id": "CP2AD_HUMAN", "id": "Q16696-1", "name": "Cytochrome P450 2A13", "aln": "----------------------------MLASGLL-----------------------LVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNS-----------------------LMKIS---ERYGPVFTIHLGP-RRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLF---KGYGVAFSN-GERAKQLRRFSIATLRGFGV-----GKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFIAKKVEHNQRTLDPNSP-RDFIDSFLIRMQEEEKNPNTE--FYLKN----LVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEA------------------KVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSI---------GKRYCFGEGLARMELFLFFTTIMQNFRFKSP--QSPKDIDVSPKHVGFATIPRNYTMSFLPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15392-1", "uniprot_id": "CP2A4_MOUSE", "id": "P15392-1", "name": "Cytochrome P450 2A4", "aln": "----------------------------MLTSGLL-----------------------LVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFVGNFLQLNTEQMYNS-----------------------LMKIS---QRYGPVFTIYLGS-RRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWLF---KGYGIAFSS-GERAKQLRRFSITTLRDFGV-----GKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSP-RDFIDSFLIRMLEEKKNPNTE--FYMKN----LVLTTLNLFFAGTETVSTTLRYGFLLLMKYPDIEA------------------KVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADLIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKSDAFVPFSI---------GKRYCFGEGLARMELFLFLTNIMQNFHFKST--QEPQDIDVSPRLVGFVTIPPTYTMSFLSR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20852-1", "uniprot_id": "CP2A5_MOUSE", "id": "P20852-1", "name": "Cytochrome P450 2A5", "aln": "----------------------------MLTSGLL-----------------------LVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNFLQLNTEQMYNS-----------------------LMKIS---QRYGPVFTIYLGP-RRIVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLF---KGYGVVFSS-GERAKQLRRFSIATLRDFGV-----GKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSP-RDFIDSFLIRMLEEKKNPNTE--FYMKN----LVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEA------------------KVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKNDAFVPFSI---------GKRYCFGEGLARMELFLFLTNIMQNFHFKST--QAPQDIDVSPRLVGFATIPPTYTMSFLSR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20812-1", "uniprot_id": "CP2A3_RAT", "id": "P20812-1", "name": "Cytochrome P450 2A3", "aln": "----------------------------MLASGLL-----------------------LVASVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNYLQLNTEKMYSS-----------------------LMKIS---QRYGPVFTIHLGP-RRVVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLF---KGYGVAFSS-GERAKQLRRFSIATLRDFGV-----GKRGIEERIQEEAGFLIESFRKTNGALIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEQNQRTLDPNSP-RDFIDSFLIRMLEEKKNPNTE--FYMKN----LVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEA------------------KVHEEIDRVIGRNRQAKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFREFLLPKGTEVFPMLGSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSDAFVPFSI---------GKRYCFGEGLARMELFLFLTNIMQNFCFKSP--QAPQDIDVSPRLVGFATIPPNYTMSFLSR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11711-1", "uniprot_id": "CP2A1_RAT", "id": "P11711-1", "name": "Cytochrome P450 2A1", "aln": "----------------------------MLDTGLL-----------------------LVVILASLSVMLLVSLWQQ-KIRGRLPPGPTPLPFIGNYLQLNTKDVYSS-----------------------ITQLS---ERYGPVFTIHLGP-RRVVVLYGYDAVKEALVDQAEEFSGRGEQATYNTLF---KGYGVAFSS-GERAKQLRRLSIATLRDFGV-----GKRGVEERILEEAGYLIKMLQGTCGAPIDPTIYLSKTVSNVISSIVFGERFDYEDTEFLSLLQMMGQMNRFAASPTGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSP-RNFIDSFLIRMQEE-KNGNSE--FHMKN----LVMTTLSLFFAGSETVSSTLRYGFLLLMKHPDVEA------------------KVHEEIEQVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPILGSLMTDPKFFPSPKDFDPQNFLDDKGQLKKNAAFLPFST---------GKRFCLGDGLAKMELFLLLTTILQNFRFKFP--MKLEDINESPKPLGFTRIIPKYTMSFMPI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15149-1", "uniprot_id": "CP2A2_RAT", "id": "P15149-1", "name": "Cytochrome P450 2A2", "aln": "----------------------------MLDTGLL-----------------------LVVILASLSVMFLVSLWQQ-KIRERLPPGPTPLPFIGNYLQLNMKDVYSS-----------------------ITQLS---ERYGPVFTIHLGP-RRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNILF---KGYGFSLSN-VEQAKRIRRFTIATLRDFGV-----GKRDVQECILEEAGYLIKTLQGTCGAPIDPSIYLSKTVSNVINSIVFGNRFDYEDKEFLSLLEMIDEMNIFAASATGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSP-RNFIDSFLIRMQEE-KYVNSE--FHMNN----LVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPDVEA------------------KVHEEIERVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPIIGSLMTEPKFFPNHKDFNPQHFLDDKGQLKKNAAFLPFSI---------GKRFCLGDSLAKMELFLLLTTILQNFRFKFP--MNLEDINEYPSPIGFTRIIPNYTMSFMPI------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56593-1", "uniprot_id": "CP2AC_MOUSE", "id": "P56593-1", "name": "Cytochrome P450 2A12", "aln": "----------------------------MLGSGLL-----------------------LLAILAFLSVMVLVSVWQQ-KIRGKLPPGPIPLPFIGNYLQLNRKDVYSS-----------------------ITQLQ---EHYGPVFTIHLGP-RRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLF---KGYGVAFSN-GERAKQLRRFSIATLRDFGM-----GKRGVEERIQEEAGCLIKMLQGTCGAPIDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLPGPQQQIIKDSHKLEDFMIQKVKQNQSTLDPNSP-RDFIDSFLIHMQKE-KYVNSE--FHMKN----LVMTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEA------------------KVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQLKKIPAFLPFST---------GKRFCLGDSLAKMELFLFFTTILQNFRFKFP--RKLEDINESPTPEGFTRIIPKYTMSFVPI------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10610-1", "uniprot_id": "CP2G1_RAT", "id": "P10610-1", "name": "Cytochrome P450 2G1", "aln": "----------------------------MALGGAF-----------------------SIFMTLCLSCLLILIAWKRTSRGGKLPPGPTPIPFLGNLLQVRIDATFQS-----------------------FLKLQ---KKYGSVFTVYFGP-RPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNF---QGYGLALSN-GERWKILRRFSLTVLRNFGM-----GKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNP-RDFIDCFLIKMYQDKSDPHSE--FNLKN----LVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEA------------------KIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSS---------GKRICVGEALARMELFLYFTSILQRFSLRSL--VPPADIDIAHKISGFGNIPPTYELCFMAR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A820-1", "uniprot_id": "D4A820_RAT", "id": "D4A820-1", "name": "Cytochrome P450", "aln": "----------------------------MEAASTW-----------------------ALLLALLLLLLALTLP--RTPARGQLPPGPTPLPLLGNLLQLRPGALYSG-----------------------FLRLS---KKYGPVFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGRGTLATLDKTF---DGHGVFFAN-GERWKQLRKFTLLALRDLGM-----GKREGEELIQEEVQNLVKAFQRTEGRPFNPSMLLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLPGPHTQLQHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQEKEDPGTE--FTEKN----LLMTVTYLLFAGTMTIGATIRYALLLLLKYPQVQK------------------RVREELIQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKHEAFLPYSL---------GKRVCLGEGLARAELWLFFTSILQAFSLDTP--CPPGDLSLKPAVRGLFNIPPDFQLQVWPTGDQSR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBX6-1", "uniprot_id": "CP2S1_MOUSE", "id": "Q9DBX6-1", "name": "Cytochrome P450 2S1", "aln": "----------------------------MEAASTW-----------------------ALLLALLLLLLLLSLTLFRTPARGYLPPGPTPLPLLGNLLQLRPGALYSG-----------------------LLRLS---KKYGPVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTLATLDKTF---DGHGVFFAN-GERWKQLRKFTLLALRDLGM-----GKREGEELIQAEVQSLVEAFQKTEGRPFNPSMLLAQATSNVVCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLPGPHTQLQHHLGTLAAFTIQQVQKHQGRFQTSGPARDVVDAFLLKMAQEKQDPGTE--FTEKN----LLMTVTYLLFAGTMTIGATIRYALLLLLRYPQVQQ------------------RVREELIQELGPGRAPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLDEDGRLRKHEAFLPYSL---------GKRVCLGEGLARAELWLFFTSILQAFSLETP--CPPGDLSLKPAISGLFNIPPDFQLRVWPTGDQSR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SQ9-1", "uniprot_id": "CP2S1_HUMAN", "id": "Q96SQ9-1", "name": "Cytochrome P450 2S1", "aln": "----------------------------MEATGTW-----------------------ALLLALALLLL-LTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSG-----------------------LMRLS---KKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTF---DGHGVFFSN-GERWRQLRKFTMLALRDLGM-----GKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTE--FTNKN----MLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQK------------------WVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSL---------GKRVCLGEGLAKAELFLFFTTILQAFSLESP--CPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33261-1", "uniprot_id": "CP2CJ_HUMAN", "id": "P33261-1", "name": "Cytochrome P450 2C19", "aln": "----------------------------MDPF---------------------------VVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKS-----------------------LTNLS---KIYGPVFTLYFGL-ERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERAN---RGFGIVFSN-GKRWKEIRRFSLMTLRNFGM-----GKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNP-RDFIDCFLIKMEKEKQNQQSE--FTIEN----LVITAADLLGAGTETTSTTLRYALLLLLKHPEVTA------------------KVQEEIERVIGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSA---------GKRICVGEGLARMELFLFLTFILQNFNLKSL--IDPKDLDTTPVVNGFASVPPFYQLCFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11712-1", "uniprot_id": "CP2C9_HUMAN", "id": "P11712-1", "name": "Cytochrome P450 2C9", "aln": "----------------------------MDSL---------------------------VVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKS-----------------------LTNLS---KVYGPVFTLYFGL-KPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERAN---RGFGIVFSN-GKKWKEIRRFSLMTLRNFGM-----GKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE--FTIES----LENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTA------------------KVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSA---------GKRICVGEALAGMELFLFLTSILQNFNLKSL--VDPKNLDTTPVVNGFASVPPFYQLCFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10632-1", "uniprot_id": "CP2C8_HUMAN", "id": "P10632-1", "name": "Cytochrome P450 2C8", "aln": "----------------------------MEPF---------------------------VVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKS-----------------------FTNFS---KVYGPVFTVYFGM-NPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRIT---KGLGIISSN-GKRWKEIRRFSLTTLRNFGM-----GKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP-RDFIDCFLIKMEQEKDNQKSE--FNIEN----LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTA------------------KVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSA---------GKRICAGEGLARMELFLFLTTILQNFNLKSV--DDLKNLNTTAVTKGIVSLPPSYQICFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08683-1", "uniprot_id": "CP2CB_RAT", "id": "P08683-1", "name": "Cytochrome P450 2C11", "aln": "----------------------------MDPV---------------------------LVLVLTLSSLLLLSLWRQSFGRGKLPPGPTPLPIIGNTLQIYMKDIGQS-----------------------IKKFS---KVYGPIFTLYLGM-KPFVVLHGYEAVKEALVDLGEEFSGRGSFPVSERVN---KGLGVIFSN-GMQWKEIRRFSIMTLRTFGM-----GKRTIEDRIQEEAQCLVEELRKSKGAPFDPTFILGCAPCNVICSIIFQNRFDYKDPTFLNLMHRFNENFRLFSSPWLQVCNTFPAIIDYFPGSHNQVLKNFFYIKNYVLEKVKEHQESLDKDNP-RDFIDCFLNKMEQEKHNPQSE--FTLES----LVATVTDMFGAGTETTSTTLRYGLLLLLKHVDVTA------------------KVQEEIERVIGRNRSPCMKDRSQMPYTDAVVHEIQRYIDLVPTNLPHLVTRDIKFRNYFIPKGTNVIVSLSSILHDDKEFPNPEKFDPGHFLDERGNFKKSDYFMPFSA---------GKRICAGEALARTELFLFFTTILQNFNLKSL--VDVKDIDTTPAISGFGHLPPFYEACFIPVQRADSLSSHL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20814-1", "uniprot_id": "CP2CD_RAT", "id": "P20814-1", "name": "Cytochrome P450 2C13, male-specific", "aln": "----------------------------MDPV---------------------------VVLLLSLFFLLFLSLWRPSSGRGKLPPGPTPLPIIGNFFQVDMKDIRQS-----------------------LTNFS---KTYGPVYTLYVGS-QPTVVLHGYEALKEALVDHGEEFSGRGRLPICEKVA---KGQGIAFSH-GNVWKATRHFTVKTLRNLGM-----GKGTIEDKVQEEAKWLVKELKKTNGSPCDPQFIMGCAPGNVICSIILQNRFDYEDKDFLNLIEKVNEAVKIISSPGIQVFNIFPILLDYCPGNHNIYFKNHTWLKSYLLEKIKEHEESLDVSNP-RDFIDYFLIERNQENANQWMN--YTLEH----LAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTA------------------KVQEEIDHVIGRHRSPCMQDRSHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFIPFSA---------GKRMCLGESLARMELFLFLTTILQNFKLKSL--VDPKDINTTPICSSLSSVPPTFQMRFIPL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56657-1", "uniprot_id": "CP240_MOUSE", "id": "P56657-1", "name": "Cytochrome P450 2C40", "aln": "----------------------------MDPF---------------------------VVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQC-----------------------LTNFS---KTYGPVFTLYFGS-QPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVS---TGKGIGFSH-GNVWKATRVFTVNTLRNLGM-----GKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEESLDVTNP-RDFIDYFLIQRRQKNGIEHMD--YTIEH----LATLVTDLVFGGTETLSSTMRFALLLLMKHTHITA------------------KVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSA---------GKRICVGESLARMELFLFLTTILQNFKLKPL--VDPKDIDMTPKHSGFSKIPPNFQMCFIPVE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56654-1", "uniprot_id": "CP237_MOUSE", "id": "P56654-1", "name": "Cytochrome P450 2C37", "aln": "----------------------------MDPI---------------------------LVLVLTLSCLFLLSLWRQSSERGKLPPGPTPLPIIGNILQIDVKDICQS-----------------------FTNLS---KVYGPVYTLYLGR-KPTVVLHGYEAVKEALVDHGEEFAGRGRFPVFDKAT---NGMGLAFSK-GNVWKNTRRFSLMTLRNLGM-----GKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLMEKLNEITKILSSPWLQICNTYPALLDYCPGSHKQFFKNYASIKNFLLEKIKEHEESLDVTIP-RDFIDYFLINGGQEDGNQPLQ--NRLEH----LAITVTDLFSAGTETTSTTLRYAILLLLKYPHVTA------------------KVQEEIEHVIGKHRSPCMQDRSRMPYTDAMIHEVQRFIDLIPNSLPHEVTSDIKFRNYFIPKGTTVITSLSSVLHDSTEFPNPEKFDPGHFLDENGKFKKSDYFIPFST---------GKRICAGEGLARMELFLFLTSILQNFNLKPL--VHPKDIDVTPMLIGLASVPPAFQLCFIPS------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64458-1", "uniprot_id": "CP2CT_MOUSE", "id": "Q64458-1", "name": "Cytochrome P450 2C29", "aln": "----------------------------MDLV---------------------------VFLALTLSCLILLSLWRQSSGRGKLPPGPTPLPIIGNFLQIDVKNISQS-----------------------FTNFS---KAYGPVFTLYLGS-KPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKII---KGFGVVFSN-GNRWKEMRRFTLMTLRNLGM-----GKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTNP-RDFIDYYLIKQKQVNHIEQSE--FSLEN----LASTINDLFGAGTETTSTTLRYALLLLLKYPDVTA------------------KVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKKSDYFMPFST---------GKRICAGEGLARMELFLILTTILQNFKLKSL--VHPKEIDITPVMNGFASLPPPYQLCFIPL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91W64-1", "uniprot_id": "CP270_MOUSE", "id": "Q91W64-1", "name": "Cytochrome P450 2C70", "aln": "----------------------------MALF---------------------------IFLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQVDVKNISKS-----------------------MGMLA---KKYGPVFTVYLGM-KPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTS---QGLGIVFSN-GETWKQTRRFSLMVLRSMGM-----GKKTIEDRIQEEILYMLDALRKTNGSPCDPSFLLACVPCNVISTVIFQHRFDYNDQTFQDFMENFHRKIEILASPWSQLCSAYP-ILYYLPGIHNRFLKDVTQQKKFILEEINRHQKSLDLSNP-QDFIDYFLIKMEKEKHNQKSE--FTMDN----LVVSIGDLFGAGTETTSSTVKYGLLLLLKYPEVTA------------------KIQEEIAHVIGRHRRPTMQDRNHMPYTDAVLHEIQRYIDFVPIPSPRKTTQDVEFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGNFKKSDYFVAFSA---------GRRACIGEGLARMEMFLILTNILQHFTLKPL--VKPEDIDTKPVQTGLLHVPPPFELCFIPV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24470-1", "uniprot_id": "CP2CN_RAT", "id": "P24470-1", "name": "Cytochrome P450 2C23", "aln": "----------------------------MELLGFT-----------------------TLALVVSVTCLSLLSVWTKLRTRGRLPPGPTPLPIIGNLLQLNLKDIPAS-----------------------LSKLA---KEYGPVYTLYFGT-SPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTH---KGYGLIFSN-GERWKVMRRFSLMTLRNFGM-----GKRSLEERVQEEARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLPGKHIEFAKRIDDVKNFILEKVKEHQKSLDPANP-RDYIDCFLSKIEEEKDNLKSE--FHLEN----LAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQA------------------KVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSL---------GKRACVGESLARMELFLFFTTLLQKFSLKTL--VEPKDLDIKPITTGIINLPPPYKLCLVPR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7UVB4-1", "uniprot_id": "A0A8N7UVB4_DANRE", "id": "A0A8N7UVB4-1", "name": "", "aln": "-------------------MAVVES-LLQFASTGT-----------------------LLGALLLFLVLYLVSSGSESQKEGKEPPGPKPLPLVGNLLTLDLTRPFDT-----------------------FFKLS---KTYGNVFQVYLGP-EKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMN---DEHGILFSN-GENWKEMRRFALSNLRDFGM-----GKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFP-WLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDP-RGFVDSFLIRKLSDEKSGKKDSYFHEEN----LMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQD------------------RVQEEIDRVIG-GRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSA---------GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKG-IVGITLNPSPHKLCAIRRS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BB11-1", "uniprot_id": "A0A8M2BB11_DANRE", "id": "A0A8M2BB11-1", "name": "", "aln": "-------------------MAVVES-LLQFASTGT-----------------------LLGALLLFLVLYLVSSGSGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDT-----------------------FFELS---KTYGNIFQVYLGP-KKTVVLVGYKTVKEALVNHAEAFGDREIGPSFRIMN---DEHGIVFSN-GENWKEMRRFALSNLRDFGM-----GKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTEPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMGLYNMFP-WLGPFLKNKRIVVRNIIQSRAQMTKLITALLETLNPNDP-RGFVDSFLIHKLSDEKSGKKNSYFHNEN----LMMNVANLFVAGTDTTGTTLRWGLMLMAKYPQIQD------------------RVQEEIDRVIG-GRQPAVEDRKKLPYTDAVIHEIQRFANIVPLNLPHTTSCDITFNGYFIKKGTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA---------GRRICLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKG-IVGITLNPSPHKLCAIRR------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PP30-1", "uniprot_id": "A0A8M9PP30_DANRE", "id": "A0A8M9PP30-1", "name": "", "aln": "-------------------MAVVES-LLQFASTSA-----------------------LLGALLLLLVLYLASSGSTSQKEGKEPPGPKPLPLVGNLLTLDLTRSFDT-----------------------FFELS---KTYGNIFQVFLGH-RKTVVLVGYKTVKEALVNYAEVFGDREIGPGFKLKD---EEHGILFSN-GENWKEMRRFALSNLRDFGM-----GKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYIDPRFTEMVARANENVRVGGSFSMMIYNIFP-WLGPFLKNRAVVVKNITQNRAEKKKLITALLETLNPHDP-RGFVDSFLIHKLSDEKSGKKDSYFHEEN----LMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQD------------------RVQEEIDRVIG-GRQPVVDDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSA---------GRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDALDLKG-IVGITLNPSPHKLCAIRRS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q8C3-1", "uniprot_id": "CP2K6_DANRE", "id": "F1Q8C3-1", "name": "Cytochrome P450 2K6", "aln": "-------------------MALIEAFLLQGSPTGT-----------------------ILGALLLFLVIYLFSSSSSSQDKEKYPPGPKPLPLLGNLHILDLKKTYLS-----------------------LLELS---KKYGPIYTVYLGP-KKVVILSGYKIVKEALVNLSEEFGDRDISPIFHDFN---RGYGIAFSN-GENWREMRRFALSTLRDFGM-----GRKRSEELIIEEIKYVKEEFEKFGGNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQIYNMFP-WLRPIVANRNQIVKNLRDTFKQNEELINGVMKTLDPFNP-RGIVDSFLIRQQKDEESGKTDSLYNSNN----LYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQA------------------KVQDEIERVIG-GRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKKGTPVFPLLVSVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGA---------GRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDDLDLTP-VVGFTLNPKPHQLCAVKRS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LXA4-1", "uniprot_id": "F1LXA4_RAT", "id": "F1LXA4-1", "name": "Cytochrome P450", "aln": "------------------MSG------FDFSAILA-----------------------LLG-LILILILNIKDFMAKASKR-QCPPGPKPWPVIGNLHILNLKRPYQT-----------------------MLELS---KKYGPIYSIQMGP-RKVVVLSGYETVKDALVNYGNQFGERSQVPIFERLF---DGKGIAFAH-GETWKTMRRFSLSTLRDFGM-----GKRTIEDTIVVECQHLIQSFESHKGKPFEIKRVLNASVANVIVSMLLGKRFDYEDPQFLRLLTLIGENIKLIGNPSIVLFNIFP-ILGFLLRSHKKVLRNRDELFSFIRRTFLEHCHNLDKNDP-RSFIDAFLVKQQ--EENNKSADYFNEEN----LLALVSNLFTAGTETTAATLRWGIILMMRYPEVQK------------------KVHDEIHKVVG-SAQPRIEHRTQMPYTDAVIHEIQRVANILPTSLPHETSTDVVFKNYYIPKGTEVITLLTSVLRDQTQWETPDAFNPAHFLSSKGRFVKKEAFMPFSV---------GRRMCAGEPLAKMELFLFFTSLMQKFTFQPPPGVSYLDLDLTP-DIGFTIQPLPHKICALLRTSAL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "S4R196-1", "uniprot_id": "S4R196_MOUSE", "id": "S4R196-1", "name": "unspecific monooxygenase", "aln": "-------------------------MFSLFSG-----------------------------MAFLAGSCLLLKLATLCWRRSHLPPGPFPFPLLGNLWQLNFQLHPNM-----------------------LFQLA---QTHGSVFTVWLGS-TPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFRDLF---GEKGVICSN-GLTWRQQRRFCLTTLRELGL-----GKQALEVQLQHEAAELAKVFLQEEGRAFDPQIPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALRHLSGPHQKIFQYHEAVRGFIRHEIIRHK--LRTAEAPKDFINCYLSQITKAIDDPVST--FSEEN----LIQVVIDLFLGGTDTTATTLHWALIYLVHHRAIQE------------------RVQQELDEMLGAAQTICYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGNFVANEAFLPFSA---------GHRVCPGEQLARMELFLMFATLLRTFQFQLPE---GSQDLGLEYVFGGTLQPQPQKICAVLRQSSLSPREP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZZX4-1", "uniprot_id": "D3ZZX4_RAT", "id": "D3ZZX4-1", "name": "unspecific monooxygenase", "aln": "-------------------------MFSLFGG-----------------------------MAFLAGSFLLLKLAALCWRRSHLPPGPFPFPLLGNLWQLNFRLHPNM-----------------------LFQLA---QTHGNVFTVWLGS-TPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDLF---GEKGVICSN-GLTWRQQRRFCLTTLRELGL-----GKQALELQLQHEAAELAEVFHQEQGRAFDPQVPIIRSTTRVIGALVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLYDMFPWALRYLSGPHQKIFQYHEAVRGFIHHEIIRHK--LRTPEAPKDFISCYLSQITKAMDDPVST--FSEEN----LIQVVIDLFLGGTDTTATTLHWAIIYLVHHRAIQE------------------RVQQELDEVLGTAQAVCYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGYYVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSA---------GHRVCPGEQLARMELFLMFATLLRTFRFQLPE---GSQGLRLEYVFGGTLQPQPQKICAVPRLSSLSPREP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "-----------------MLADSYLIKFVLRQLQVQQDGD--------------AQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRF------------------------MELA---KQYGSLFSTRLGS-QLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLN----GYGIINST-GKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNN-IRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMR------------------RVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGV---------GRRMCLGDVLARMELFLFFASFMHCFDIALPE---GQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** * :* . * : ::. :: : *. : : :: :* : : * . : . . . : : . : :* . : :. * : : : *: :. :* : : * : . : . : . : : . : * .*:. . :.:. * * * * :. *:: .:: . ", "identical_positions": 22, "similar_positions": 66, "identity": "3.46%" }, { "cls_id": "homologset.agr.FB:FBgn0010387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31786-1", "uniprot_id": "ACBP_MOUSE", "id": "P31786-1", "name": "Acyl-CoA-binding protein", "aln": "MS-QAEFDKAAEEVKRLKTQPTDEEMLFIYSHFKQATVGDVNTDRPGLLDLKGKAKWDSWNKLKGTSKESAMKTYVEKVDELKKKYG--I--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11030-1", "uniprot_id": "ACBP_RAT", "id": "P11030-1", "name": "Acyl-CoA-binding protein", "aln": "MS-QADFDKAAEEVKRLKTQPTDEEMLFIYSHFKQATVGDVNTDRPGLLDLKGKAKWDSWNKLKGTSKENAMKTYVEKVEELKKKYG--I--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5Y857-1", "uniprot_id": "A0A8I5Y857_RAT", "id": "A0A8I5Y857-1", "name": "Acyl-CoA-binding protein", "aln": "MS-QAEFDKAAEEVKCLKTQPMDEEMLFIYSHFKQATVGDINTDRPGLLDLKGKAKWDSWNKLKGTSKKNAMKTYVEKVCLLLKKKKRFIKLKLLIVFYLKPNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07108-1", "uniprot_id": "ACBP_HUMAN", "id": "P07108-1", "name": "Acyl-CoA-binding protein", "aln": "MS-QAEFEKAAEEVRHLKTKPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDAWNELKGTSKEDAMKAYINKVEELKKKYG--I--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D258-1", "uniprot_id": "ACBD7_MOUSE", "id": "Q9D258-1", "name": "Acyl-CoA-binding domain-containing protein 7", "aln": "MSLQADFDQAAQDVRKLKSRPEDEELKELYGLYKQSVIGDINIACPAMLDLKGKAKWEAWNLQKGLSKEDAMCAYISKARELIEKYG--I--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31787-1", "uniprot_id": "ACBP_YEAST", "id": "P31787-1", "name": "Acyl-CoA-binding protein", "aln": "MV-SQLFEEKAKAVNELPTKPSTDELLELYALYKQATVGDNDKEKPGIFNMKDRYKWEAWENLKGKSQEDAEKEYIALVDQLIAKYSS----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42281-1", "uniprot_id": "ACBP_DROME", "id": "P42281-1", "name": "Acyl-CoA-binding protein homolog", "aln": "MV-SEQFNAAAEKVKSLTKRPSDDEFLQLYALFKQASVGDNDTAKPGLLDLKGKAKWEAWNKQKGKSSEAAQQEYITFVEGLVAKYA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *: *: *. * .:* :*: :*. :**: :** : *.::::..: **::*: ** *.: * *: . * * ", "identical_positions": 23, "similar_positions": 29, "identity": "22.12%" }, { "cls_id": "homologset.agr.FB:FBgn0010389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498D6-1", "uniprot_id": "FGFR4_RAT", "id": "Q498D6-1", "name": "Fibroblast growth factor receptor 4", "aln": "-----------------------------------------------------------------------------------------------MWLLLALLSIFQETP--------------AFSLEASEEMEQEPCPAPISEQQEQVLTVALGQPVRLCCGRTERGRH----WYKEGSRLASAGRVRGWRGRLEIASFLPEDAGRYLCLARG-SMTVVHNLTLIMDDSLPSINN-EDPKTLSSSSSG-----HSYLQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPMPTIHWLKNGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENSLGSIRYSYLLDVLERSPHRPILQAGLPANTTAVVGSNVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTTDINSSE--VEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPAEEEDLAWTTATSEARYTDIILYVSGSLALVLLLLLAGVYHRQ-AIHGHHS-RQPVTVQKLSR-FPLAR--QFSLESRSSGKSSLSLVRGVR---LSSSGPPLLTGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYAAKGNLREFLRARRPPGPDLSPDGPRSSEGP----LSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGG-SPYPGIP-VEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS-EEYLDLRLTFG-PYSPNNGDASST-CSSS-DSVFSHDPLPLEPSPFPFPEAQTT--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03142-1", "uniprot_id": "FGFR4_MOUSE", "id": "Q03142-1", "name": "Fibroblast growth factor receptor 4", "aln": "-----------------------------------------------------------------------------------------------MWLLLALLSIFQGTP--------------ALSLEASEEMEQEPCLAPILEQQEQVLTVALGQPVRLCCGRTERGRH----WYKEGSRLASAGRVRGWRGRLEIASFLPEDAGRYLCLARG-SMTVVHNLTLLMDDSLTSISNDEDPKTLSSSSSG-----HVYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPMPTIHWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENSLGSIRYSYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHVVINGSSFGADGFPYVQVLKTTDINSSE--VEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLP--EEDLTWTTATPEARYTDIILYVSGSLVLLVLLLLAGVYHRQ-VIRGHYS-RQPVTIQKLSR-FPLAR--QFSLESRSSGKSSLSLVRGVR---LSSSGPPLLTGLVNLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGP----LSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTLGG-SPYPGIP-VEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS-EEYLDLRLTFG-PFSPSNGDASST-CSSS-DSVFSHDPLPLEPSPFPFSDSQTT--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22455-1", "uniprot_id": "FGFR4_HUMAN", "id": "P22455-1", "name": "Fibroblast growth factor receptor 4", "aln": "-----------------------------------------------------------------------------------------------MRLLLALLGVLLSVPGPP-----------VLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGH----WYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARG-SMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNR-----HSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSE--VEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLP--EEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQ-ALHGRHP-RPPATVQKLSR-FPLAR--QFSLESGSSGKSSSSLVRGVR---LSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGP----LSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGG-SPYPGIP-VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS-EEYLDLRLTFG-PYSPSGGDASST-CSSS-DSVFSHDPLPLGSSSFPFGSGVQT--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LSG7-1", "uniprot_id": "F1LSG7_RAT", "id": "F1LSG7-1", "name": "Fibroblast growth factor receptor", "aln": "-------------------------------------------------------------------MGLPSTWRYGTGPGIGTVTMVSWGRFI-CLVLVTMATLSLARPSFS--------------LVEDTTLEPEEPPTKYQISQPEACVVAPGESLELRCMLK-DAAV--ISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACAAARTVDSETLYFMVNVTDAISSG-DDEDDTDSSED----FVSENRSNQRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSN--AEVLALFNVTEMDAGEYICKVSNYIGQANQSAWLTVLPKQQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMK-TTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTR-LSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQ----MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLE-QYSPSYPDTRSS-CSSGDDSVFSPDPMPYDPCLPQYP--HING-SVKT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21803-1", "uniprot_id": "FGFR2_MOUSE", "id": "P21803-1", "name": "Fibroblast growth factor receptor 2", "aln": "--------------------------------------------------------------------------------------MVSWGRFI-CLVLVTMATLSLARPSFS--------------LVEDTTLEPEEPPTKYQISQPEAYVVAPGESLELQCMLK-DAAV--ISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARTVDSETWIFMVNVTDAISSG-DDEDDTDSSED----VVSENRSNQRAPYWTNTEKMEKRLHACPAANTVKFRCPAGGNPTSTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKNGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLP---APVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMK-TTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTR-LSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQ----MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLE-QYSPSYPDTSSS-CSSGDDSVFSPDPMPYEPCLPQYP--HING-SVKT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21802-1", "uniprot_id": "FGFR2_HUMAN", "id": "P21802-1", "name": "Fibroblast growth factor receptor 2", "aln": "--------------------------------------------------------------------------------------MVSWGRFI-CLVVVTMATLSLARPSFS--------------LVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLK-DAAV--ISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSG-DDEDDTDGAED----FVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLP---APGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMK-NTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTR-LSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQ----MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE-QYSPSYPDTRSS-CSSGDDSVFSPDPMPYEPCLPQYP--HING-SVKT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JG38-1", "uniprot_id": "FGFR2_DANRE", "id": "Q8JG38-1", "name": "Fibroblast growth factor receptor 2", "aln": "--------------------------------------------------------------------------------------MFARGWLLGALLLMTLATVSVARPSLK--------------IDLVNTSAPEEPPTKNQNCVPVLFSVHPGELLKLKCPLS-GADD--VVWTKDSSSLRPDNRTLVARDWLQISDATPKDSGLYSCSATGLRDCDVFSFIVNVTDAISSG-DDEDDTERSDD----VGADG-EQMRLPYWTFPEKMEKKLHAVPAANTVKFRCAAAGNPKPKMRWLKNAKPFRQEDRMGGYKVRLQHWTLIMESVVPSDKGNYTCLVENQYGSIDHTYTLDVVERSPHRPILQAGLPANVTVQVGQDAKFVCKVYSDAQPHIQWLQHYTKNGSCCGPDGLPYVRVLKTAGVNTTDKEIEVLYLPNVTFEDAGEYTCLAGNSIGISYHTAWLTVHP---AETNPIETDYPPDYVEIAIYCIGVFLIACMVVIVVVCRMR-TSAKKPDFSSQPAVHKLTKQIPLRRQVTVSSDSSSSMSSSTPLVRITTR-RSSAHDDP----IPEYDLPEDPRWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEP----LTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMKDCWHAISSHRPTFKQLVEDLDRILTLATNEEYLDLCAPVE-QYSPSFPDTRSS-CPSGDDSVFSHDPLADEPCLPKYQ--HING-GIKT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04589-1", "uniprot_id": "FGFR1_RAT", "id": "Q04589-1", "name": "Fibroblast growth factor receptor 1", "aln": "----------------------------------------------------------------------------------------------MWGWRGLLFWAVLVTATLC--------------TARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQS--INWLRDGVQLAESNRTRITGEEVEVRDSIPADSGLYACVTNSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPSPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYDQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEAL---EERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMK-SGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSR---LSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQ----LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGG-SPNPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLD-QDSPSFPDTRSSTCSSGEDSVFSHEPFPEEPCLPRHPTQLANG-GLNRR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16092-1", "uniprot_id": "FGFR1_MOUSE", "id": "P16092-1", "name": "Fibroblast growth factor receptor 1", "aln": "----------------------------------------------------------------------------------------------MWGWKCLLFWAVLVTATLC--------------TARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQS--INWLRDGVQLVESNRTRITGEEVEVRDSIPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEAL---EERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMK-SGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSR---LSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQ----LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGG-SPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPLD-QYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTQLANS-GLKRR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11362-1", "uniprot_id": "FGFR1_HUMAN", "id": "P11362-1", "name": "Fibroblast growth factor receptor 1", "aln": "----------------------------------------------------------------------------------------------MWSWKCLLFWAVLVTATLC--------------TARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQS--INWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEAL---EERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMK-SGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSR---LSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQ----LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGG-SPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLD-QYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANG-GLKRR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z00-1", "uniprot_id": "FGR1A_DANRE", "id": "Q90Z00-1", "name": "Fibroblast growth factor receptor 1-A", "aln": "-------------------------------------------------------------------------------------------MKMMMIMKTTLLLISVLLTQAL--------------QSQGRPAIQDEAP-----AEPTSYTLDSGEKLELSCKAKEDTQK--VTWTKDLVPLVDGEHTRLRNDQMEIEKVEPTDSGLYACFAQGLNSNHTEYFNISVT-------DEEDEVDSSSEEAKLSNDQ--NLPMAPVWAQPDKMEKKLHAVPASKTVKFRCQANGNPTPTLKWLKNGKEFKRDQRIGGFKVREHMWTIIMESVVPSDRGNYTCLVENRHGSINHTYQLDVVERSPHRPILQAGLPANRTAVVGSDVEFECKVFSDPQPHIQWLKHIEVNGSRYGPDGLPYVRALKTAGVNTTDKEMEVLQIRNVSLEDAGEYTCLAGNSIGHSHHSAWLTVYKA-----VPPTQLPNQTYLEVLIYCVGFFLICVMVGTAVLAKMH-SSAKKSDFNSQLAVHKLAKSIPLRRQVTVSVDSSSSMHSGGMLVRPSR---LSSSGSPMLSGVSEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVEN----MSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGG-SPYPGVP-VEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRTLSMTSNQEYLDLSVSLD-QFSPNFPDTRSSTCSSGEDSVFSHDAGADEPCLPKFPPHPNRGVAFKKR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NUM7-1", "uniprot_id": "A0A8M1NUM7_DANRE", "id": "A0A8M1NUM7-1", "name": "Fibroblast growth factor receptor", "aln": "------------------------------------------------------------------------------------MIFLSAAVSLRMLKSWRLLVLLLILTQLC--------------TVQSRPAVTEQG------------------------------------------------------------------------------------HIVASS-------EDEDDDESSSEENKPSSSQE-LLPMAPRWAQPEKMEKKLHAVPASKTVKFRCQAEGNPIPKLRWLKNGKEFKRDQRIGGYKLREHMWTIIMESVVPSDKGNYTCLVENEYGSINHTYQLDVVERSPHRPILYAGLPANRTAVVGSDVEFVCKVFSDPQPHIQWLKHIRVNGSQLGPDGLPYVRVLKTAGLNTTDKEMEVLQLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVVKAP----TAPSAVPSQSYLEVLIYCIGFFLIFLMVGIATIVKIR-SSSKKSDFNSQLAVHKLAKSIPLRRQITVSVESSSSLNSGVMLVRPSR---LSSSGTPMLSGVSEYELPQDPCWEVSRERLVLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPDPLPIES----MSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGG-SPYPGVP-VEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDLDRTLSLISNQEYLELSVPLEPMYSQVILNERSSTCSSEQDSVFLQEPGPEDPCIPPSQ-QPMR--SFKKR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LSN4-1", "uniprot_id": "F1LSN4_RAT", "id": "F1LSN4-1", "name": "Fibroblast growth factor receptor", "aln": "----------------------------------------------------------------------------------------MVVPACVLVFCVAV--VAGVTSEPP--------------GPEQRVGRRAAEVPGPEPSQQEQVAFGSGDTVELSCHPPGGAPTGPTLWAKDGVGLVASHRILVGPQRLQVLNATHEDAGVYSCQ-QRLTRRVLCHFSVRVTDAPSSG-DDED-GEDVAEDT-----------GAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDRELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAE--EELMEVDEAGSVYAGVLSYGVGFFLFILVVAAVTLCRLR-SPPKKG--LGSPTVHKVSR-FPLKRQ-QVSLESNSSMNSNTPLVRIAR---LSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQ----LTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFE-QYSPGGQDTPSS-SSSGDDSVFTHDLLPPGP--------PSNG-GPRT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61851-1", "uniprot_id": "FGFR3_MOUSE", "id": "Q61851-1", "name": "Fibroblast growth factor receptor 3", "aln": "----------------------------------------------------------------------------------------MVVPACVLVFCVAV--VAGATSEPP--------------GPEQRVVRRAAEVPGPEPSQQEQVAFGSGDTVELSCHPPGGAPTGPTVWAKDGTGLVASHRILVGPQRLQVLNASHEDAGVYSCQ-HRLTRRVLCHFSVRVTDAPSSG-DDED-GEDVAEDT-----------GAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAILGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAE--EELMETDEAGSVYAGVLSYGVVFFLFILVVAAVILCRLR-SPPKKG--LGSPTVHKVSR-FPLKR--QVSLESNSSMNSNTPLVRIAR---LSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQ----LTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIP-VEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFE-QYSPGGQDTPSS-SSSGDDSVFTHDLLPPGP--------PSNG-GPRT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22607-1", "uniprot_id": "FGFR3_HUMAN", "id": "P22607-1", "name": "Fibroblast growth factor receptor 3", "aln": "----------------------------------------------------------------------------------------MGAPACALALCVAVAIVAGASSESL--------------GTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCR-QRLTQRVLCHFSVRVTDAPSSG-DDED-GEDEAEDTG-------VDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAE--EELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLR-SPPKKG--LGSPTVHKISR-FPLKR--QVSLESNASMSSNTPLVRIAR---LSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQ----LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFE-QYSPGGQDTPSS-SSSGDDSVFAHDLLPPAP--------PSSG-GSRT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8X3-1", "uniprot_id": "FGFR3_DANRE", "id": "Q9I8X3-1", "name": "Fibroblast growth factor receptor 3", "aln": "-----------------------------------------------------------------------------------------MVPLCLLLYLATLVFPPVYSAHLL--------------SPEP-----TDWVSSEVEVFLEDYVAGVGDTVVLSCTP--QDFLLPIVWQKDGDAVSSSNRTRVGQKALRIINVSYEDSGVYSCR-HAHKSMLLSNYTVKVIDSLSSG-DDEDYDEDEDEAGN-------GNAEAPYWTRSDRMEKKLLAVPAANTVKFRCPAAGNPTPSIHWLKNGKEFKGEQRMGGIKLRHQQWSLVMESAVPSDRGNYTCVVQNKYGSIKHTYQLDVLERSPHRPILQAGLPANQTVVVGSDVEFHCKVYSDAQPHIQWLKHIEVNGSQYGPNGAPYVNVLKTAGINTTDKELEILYLTNVSFEDAGQYTCLAGNSIGYNHHSAWLTVLPAV--EMEREDD-----YADILIYVTSCVLFILTMVIIILCRMW-INTQKT--LPAPPVQKLSK-FPLKR--QVSLESNSSMNSNTPLVRIAR---LSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNET----LTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLSMTSTDEYLDLSVPFE-QYSPTCPDSNST-CSSGDDSVFAHDPLPEEPCLPKHH--HSNG-VIRT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90413-1", "uniprot_id": "FGFR4_DANRE", "id": "Q90413-1", "name": "Fibroblast growth factor receptor 4", "aln": "MLSILKVFIAICFMELVCSRSITSGEPRAKDIRVSRHILTPGYPENATVLVGGHVKLVCKLHQPASTRLQWFKKDSNRLGPDGSPVLTALTPLLENLSKVNIFPLVNISLEDAGEYVCKAENSAGQATRSAWVEVLSEVSEEPTEEPSEHLLLELGDVLKLRCDTN---RPGAVQWFKSGVRVQHNARIQIRAAVMEIADVTYEDSGVYVCMLRG-TKEALRNFTITVADAVGSG-DDDDEDNGLDDIGPETENDQVYISRAPYWTHTQRMEKKLYAVPAGNTVKFRCPATGSPLPTIRWLKNGREFRGEHRIGGIKLRHQHWSLVMESVVPSDRGNYSCVVENKYGSIAHTYLLDVLERSPHRPILQAGLPKNTTAIVGGDAQFLCKVYSDAQPHIQWLKHIEMNGSRYGPDGIPYVKIVKTGSLNMSE--VEVLYLTNISMEDAGEYSCLAGNSIGFSHQSAWLTVLSEE--DVAKEVDLMEAKYTDIIIYASGFLALVMAIVIVVLCRMQ-VHPSREPFDTLP-VQKLSK-FPLRR--QYSVESNSSGKSSASLMRVAR---LSSSCSPMLAGVMEFELPYDPDWEFPRENLTLGKPLGEGCFGQVVRAEAYGINKENQDHMATVAVKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDGPLYVLVEYASKGSLREYLRARRPPGMDYTFDVTKVPEEQ----LTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNVLVTEDNVMKIADFGLARGVHQIDYYKKTTNGRMPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPSNCTHELYMKMRECWHAVPTQRPTFKQLVEELDRVLVSIS-DEYLDLSTPFE-QYSPSCEDTSSS-CSSDNDSVFTHDALSTEPCLLGYHDVHSRMDLKTTMR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07407-1", "uniprot_id": "FGFR1_DROME", "id": "Q07407-1", "name": "Fibroblast growth factor receptor homolog 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MAAAWSWRASHSTITMTSGSLVVLFLLLS---------------IWQPAVQVEGRRQMANSQEMIKDHLGARSQNKTPAITNNANQSSTSSADLDDGAADDDDNKADLPVNVS----------SKPYWRNPKKMS-FLQTRPSGSLLTLNCHALGNPEPNITWYRNG---TVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTG-PLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCSNN------------RSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVN---------NAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQ-QPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDT---PPSTSDEEED--ETDNLQKWCNY-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* * * ..:*. * : *:.. : :.* : *.* ..: * ::. : * :: *:: *:. **.* *.*:* * * *.* : * :* *:*** :* * * : :. .: ** ** .: *: . : . : . : * : *: : * * * .* :* :*:* * : : . : . : ::: :: . : : . .* : ::* . . ::* *. **. * .*.** .****.**:*: .*. *****:*.. ::.*::.*: ***:**::.:* ******* *:* *****:** *.:*.*:::* .** * : : . :: *:. ::*:****:** *::***** *******::. *:*********.:: ***:*.:***:*:******:* ::.* :*****: :*:***:* * .* * : .***:. * .*:**::*. *. ::* *::**: . .**.* ::** *: : ::: . : . : . : ", "identical_positions": 181, "similar_positions": 180, "identity": "19.09%" }, { "cls_id": "homologset.agr.FB:FBgn0010391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBG7-1", "uniprot_id": "SRPRA_MOUSE", "id": "Q9DBG7-1", "name": "Signal recognition particle receptor subunit alpha", "aln": "MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQER-GGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESS--KIRAPTTMKKFEDSEKAKKPVRSMIETRGEKTKEKAKNNKKRGAKKEGSDGTLATSKTAPAEKSGLSAGPENG-ELSKEELIRRKREEFIQKHGKGLDKSSKSTKSDTPKEKGKKAPRVWELGG-CANKEVLDYSTPTTNGTPEAALSEDIN--LIRGTGPGGQLQDLDCSS---SDDEGATQN----TKPSATKGTLGGMFGMLKG-LVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQR------PYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLTALHPPEKHGG---------RTMVQLFEKGYG--KDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08240-1", "uniprot_id": "SRPRA_HUMAN", "id": "P08240-1", "name": "Signal recognition particle receptor subunit alpha", "aln": "MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQER-GGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESS--KIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGG-CANKEVLDYSTPTTNGTPEAALSEDIN--LIRGTGSGGQLQDLDCSS---SDDEGAAQNS---TKPSATKGTLGGMFGMLKG-LVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQR------PYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGG---------RTMVQLFEKGYG--KDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9U5L1-1", "uniprot_id": "SRPRA_DROME", "id": "Q9U5L1-1", "name": "Signal recognition particle receptor subunit alpha homolog", "aln": "MLDFVVIFTKGGVVLWHSNASGNSFASCINSLIRGVILEERNTEAKYYEEDHLAVQFKLDNELDLVYAAIFQKVIKLNYLDGFLADMQAAFKEKYG-DIR-------LGDDYDFDREYRRVLSAAEEASAKQVKAPKTMRSYNESQKSKKTVASMIQD-DKKPVEKRVN----------------IQEAPPPSKS-QPSSPPTG--SPMDKIIMEKRRKLREKLTPTKKTSPSDSKSSKPEKAGKK-PRVWDLGGNSKDAALLDRSR----DSPDDVQYQNIN--SELVGTMQGVIRDLDVESEDEADNEDASSEGEAEEQVQSKKGKRGGLLSYFKG-IVGAKTMSLADLQPALEKMRDHLISKNVASEIAAKLCDSVAASLDGKQMGTFDSIASQVKEALTESLVRILSPKRRIDIIRDALESKRNGR------PYTIIFCGVNGVGKSTNLAKICFWLIENDFNVLIAACDTFRAGAVEQLRTHTRHLNALHPAAKHDG---------RNMVQLYEKGYG--KDAAGIAMEAIKFAHDTRVDVVLVDTAGRMQDNEPLMRSLSKLIKVNNPDLVLFVGEALVGNEAVDQLVKFNQSLADYSSNENPHIIDGIVLTKFDTIDDKVGAAISMTYITGQPIVFVGTGQTYADLKAINVNAVVNSLMK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32916-1", "uniprot_id": "SRPR_YEAST", "id": "P32916-1", "name": "Signal recognition particle receptor subunit alpha homolog", "aln": "MFDQLAVFTPQGQVLYQYNCLGKKFSEIQINSFISQLITSP-VTRKESVANANTDGFDFN-------------LLTINSEHKNSPSFNALFYLNKQPELYFVVTFAEQTLELNQETQQTLALVLKLWNS-LHLSESILKNRQGQNEKNKHNYVDILQGIEDDLKKFEQYFR------------IKYEESIKQDHINPDNFTKNG------SVPQSHNKNTKKKLRDTKGKKQSTGNVGSGRKWGRDGGMLDEMNH--EDAAKLDFSSSNSHNSSQVALDSTINKDSFGDRTEGGDFLIKEIDDLLSSHKDEITSGN-----EAKNSGYVSTAFGFLQKHVLGNKTINESDLKSVLEKLTQQLITKNVAPEAADYLTQQVSHDLVGSKTANWTSVENTARESLTKALTQILTPGVSVDLLREIQSKRSKKDEEGKCDPYVFSIVGVNGVGKSTNLSKLAFWLLQNNFKVLIVACDTFRSGAVEQLRVHVENLAQLMDDSHVRGSKNKRGKTGNDYVELFEAGYGGSDLVTKIAKQAIKYSRDQNFDIVLMDTAGRRHNDPTLMSPLKSFADQAKPDKIIMVGEALVGTDSVQQAKNFNDAFGKG------RNLDFFIISKCDTVGEMLGTMVNMVYATGIPILFVGVGQTYTDLRTLSVKWAVNTLMS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* ..:*: * **: : ... : : . :: . : : : :.:: ::.:. . ..: * : :: : : : * * :: . . :.:* *: .::: .. : .:. .: . .* .: :..: :* .. . : . .: *:. : ::. : ** * .:.: . . ** * : : .. :..: :. ..* . :. :: ::* *::. *::..*:*: ::**:****.: * * :.*: .* *. ..: :: . .:::* ::*.:** * :*::*: . : . **.. : ***********:*:.***::*.*.***.******:*******.*...* * : * . *:*:* *** . .: ** :** :::: .*:**:***** ::: .** .* .: .** :::*******.::*:* :** ::.. : :* ::::* **:.: :*: :.*.* *. **:***.**** **:::..: .* :**. ", "identical_positions": 139, "similar_positions": 223, "identity": "20.81%" }, { "cls_id": "homologset.agr.FB:FBgn0010395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64632-1", "uniprot_id": "ITB4_RAT", "id": "Q64632-1", "name": "Integrin beta-4", "aln": "----------------MAGLCSSPWVK-LLLAVVLSAGLPGNMANRCKKAQVKSCTECIRVDKSCAYCTDELFK------ERRCNTQADVLAAGCRGESVLVMESS-----LEITENIQIDTSLHRSQVSPQGLQVRLRPGEERNFVFKVFEPLESPVDLYILMDFSNSMSDDLDNLKQMGQNLAKILRQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPN------SDPPFSFKNVISLTENVEEFWDKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRADSTHLLVFSTESAFHYEADGANVLAGIMNRNDEKCHLDATGAYTQYKTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHKYFPVS-SLGVLQEDSSNIVELLEEAFYRIRSNLDIRALDSPRGLRTEVTSDTLQKTETGSFHIKRGEVGTYNVHLRAVEDIDGTHVCQLAKEDQRGNIHLKP-SFSDGLRMDASVICDMCACELQKEVQSARCHYRGDFMCGHCVCNEGWSGKTCNCSTG--SLSDTQPCLREGE---------DKPCSGHGECQCGRCVCYGE--GRYEGHFCEYDNFQCPRTSGFLCNDRGRCSMGECVCEPGWTGRSCDCP--------LSNATCIDSNGGICNGLGFCECGRCHCNQRSS------LYTDTTCEINYSAIRLGLCEDLRSCVQCQAWGTGE-KKGRTCEECNFKVKMVDELKKAEEVVEYCSFRDEDDDCTYSYTVEG-DGSPGPNSTVLVHKKKDCLPAPSWWLIPLLIFLLLLLVLLLLLCWKYCACCKACLGLLPCCNQGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDTVRWKITNNVQR-PGFATHAASISPTELVPYGLSLRLGRLCTENLMKPGTRECDQLRQEVEENLNEVYRQVNGVHKLQQTKFRQQPNAGKKQDHTIVDTVLLAPRSAKQSLLKLTEKQVEQGSFHELKVAPGYYTLTAEQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPVGTATLGRRLVNITIIKEQASGIVSFEQPEYSVSRGDQVARIPVIRHILDNGKSQVSYSTQDNTAHGHRDYVPVEGELLFYPGETWKELQVKLLELQEVDSLLRGRQVRRFQVQLSNPKFGARLGQPNTATVIIGEQDE---------------------------------------------------------------------------------------------------------------TDRSLINEISASPPLPRGDLGAPQNPNAKAAGSRKIHFNWLPPPGKPMGYRVKYWVQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAHGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNEDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQGGEDYENFLMYSDDVLRSPASSQRPSVSDDT-----------------------------------------------------------------------EHLVNG--RMDFAYPG-SANSLHRMTAAN-VAYGTHLSPHQTHRMLSTSSTLTRDYHSLTRTDHSQSGTLPRDYSTLTSLSSQGLPPIWEDGRSRLPLSWTLG-----------SWSRAQMKGVPASRGSPDSIILAGQSAAPSWGTDSRGAMGVPDTPTRLVFSALGPTSLKVSWQEPQCDRALLGYSVEYQLLNGGEMHRLNIPNPGQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDILGYLVTCEMAQGGGPARTFRVDGDNPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSHSGLFQNPLQSEYSTVTSTHSTTTTEPFLIDG---LTLGTQRLEAGGSLTRHVTQEFVSRTLTTSGSLSTHMDQQFFQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A863-1", "uniprot_id": "ITB4_MOUSE", "id": "A2A863-1", "name": "Integrin beta-4", "aln": "----------------MAGPCCSPWVKLLLLAAMLSASLPGDLANRCKKAQVKSCTECIRVDKSCAYCTDELFK------ERRCNTQAELLAAGCRGESILVMESS-----LEITENTQIDTSLHRSQVSPQGLQVRLRPGEERSFVFQVFEPLESPVDLYILMDFSNSMSDDLDNLKQMGQNLAKILRQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPN------SDPPFSFKNVISLTENVEEFWNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRADSTHLLVFSTESAFHYEADGANVLAGIMNRNDEKCHLDASGAYTQYKTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHKYFPVS-SLGVLQEDSSNIVELLEEAFYRIRSNLDIRALDSPRGLRTEVTSDTLQKTETGSFHIKRGEVGTYNVHLRAVEDIDGTHVCQLAKEDQGGNIHLKP-SFSDGLRMDASVICDVCPCELQKEVRSARCHFRGDFMCGHCVCNEGWSGKTCNCSTG--SLSDTQPCLREGE---------DKPCSGHGECQCGRCVCYGE--GRYEGHFCEYDNFQCPRTSGFLCNDRGRCSMGECVCEPGWTGRSCDCP--------LSNATCIDSNGGICNGRGYCECGRCHCNQQS-------LYTDTTCEINYSAIRLGLCEDLRSCVQCQAWGTGE-KKGRACDDCPFKVKMVDELKKAEEVVEYCSFRDEDDDCTYSYNVEG-DGSPGPNSTVLVHKKKDCPPGSFWWLIPLLIFLLLLLALLLLLCWKYCACCKACLGLLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDTVRWKITNNVQR-PGFATHAASTSPTELVPYGLSLRLGRLCTENLMKPGTRECDQLRQEVEENLNEVYRQVSGAHKLQQTKFRQQPNTGKKQDHTIVDTVLLAPRSAKQMLLKLTEKQVEQGSFHELKVAPGYYTVTAEQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPVGTATLGRRLVNITIIKEQASGVVSFEQPEYSVSRGDQVARIPVIRHILDNGKSQVSYSTQDNTAHGHRDYVPVEGELLFHPGETWKELQVKLLELQEVDSLLRGRQVRRFQVQLSNPKFGARLGQPSTTTVILGEHDE---------------------------------------------------------------------------------------------------------------TDRSLINQTLSSPPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPPGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNEDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQGGEDYENFLMYSDDVLRSPASSQRPSVSDDTG-CGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSDEDGSVAG-----GVEGEGSGWIRGATPRPPGEHLVNG--RMDFAYPG-SANSLHRMTAAN-VAYGTHLSPHLSHRVLSTSSTLTRDYHSLTRTEHSHSGTLPRDYSTLTSLSSQ----------------------------------------------------------------DSRGAVGVPDTPTRLVFSALGPTSLKVSWQEPQCDRMLLGYSVEYQLLNGGEMHRLNIPNPGQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDILGYLVTCEMAQGGAPARTFRVDGDNPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQVGGPFPQLGSHSGLFQNPVQSEFSSVTSTHS-TTTEPFLMDG---LTLGTQRLEAGGSLTRHVTQEFVTRTLTASGSLSTHMDQQFFQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16144-1", "uniprot_id": "ITB4_HUMAN", "id": "P16144-1", "name": "Integrin beta-4", "aln": "----------------MAGPRPSPWAR-LLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFR------DRRCNTQAELLAAGCQRESIVVMESS-----FQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFELEVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEPWPN------SDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVS-SLGVLQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSFHIRRGEVGIYQVQLRALEHVDGTHVCQLP-EDQKGNIHLKP-SFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTG--SLSDIQPCLREGE---------DKPCSGRGECQCGHCVCYGE--GRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCP--------LSNATCIDSNGGICNGRGHCECGRCHCHQQS-------LYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGE-KKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEG-DGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQR-PGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLKLTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFGAHLGQPHSTTIIIRDPDE---------------------------------------------------------------------------------------------------------------LDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTG-CGWKFEPLLGEELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNG--RMDFAFPG-STNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSH----------------------------------------------------------------DSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTTHT-SATEPFLVDG---LTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQQFFQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TT67-1", "uniprot_id": "A0AB32TT67_DANRE", "id": "A0AB32TT67-1", "name": "Integrin beta", "aln": "----------------MGGWAIRLAVG-IFLLLLAATDSRADEVNHCTAARTKTCSECIQVGAGCAYCPDEVFE------HERCDLKENLEAQKCS--KIVNFESS-----RQIQENVKINEQLKQSQVSPQLMSMTLLPGEEKEVEMEVFEPTRGPLDLYILMDFSNSMSDDLDNLKRMGEKLARLVGDLSDDYTIGFGKFVDKVTEPQTDMRPAKLAEPWSN------SDPPFSFRNVIKLTSNITSFRQKLQKERISGNLDAPEGGFDAILQTAVCQDQIGWRKDSTHLLVFSTESAFHYEADGANVLAGILDRNDEQCHLNVDGNYTHDVRQDYPSIPTLVRLLVKHNIIPIFAVTNHSYSYYEKLHEYFPIA-ELGQLQEDSSNILSILEKAFENIRSKISIRAEDRPKAVETKIFSQSGTFSEYGNFKITPGQTGKFKVRMKALNQVGEEPVCKVNQADRAGTLRVKPTTFSSAFKINAEVLCPTCDCEKTPVKNAVRCTGHGDLVCGKCQCYAGWLGPLCNCSAG--ASTDSVMCIERGK---------TEPCSGRGDCMCGTCVCYNP--NQFEGPYCQFDKSQCQRFGGFLCNERGSCSMGRCVCSPGWSGEACECP--------TSNDSCRDSKGGICNDRGVCKCGRCECEHSG-------LPLSPTCEANF-QQQVGMCEAKRSCVQCQAWSTGE-RKGRKCDECPFKIVRVDELEEDKNVIETCSFRDEDDDCTYHYNVNYPSNITDKEHRVLVKKKKDCPPAGFLWLIPLIMFLMLLLGLLLLCCWKYCACCQSCLALLPCCARGRMVGFKENQYLLRQSFLQNDYLDTPMVRSGPLKSTDVVRWKVADNVHRGTNHPQNQIRPNPKETIQYPVSLRLNRQFSEVLSNPDARDTDMLRREVEDNLNDVFLQIPGAQPVQKTLFRTQRNSGKRQNNTIVDTVLSAPRSSYPDIVKLTDKQVQSGNFRDLKVIPGYYTVASDKEAAGAVEFPENVESVDVRVPLFIKDEDDEKKELLVQAVDVPVGIAKIGKDHVNITVLKEQASSVFTFLEPSYTYSRQDGVANIPIKRQIIEDGRAQVTYSTADLTAKDKKDYISVDGDLSYGAGETEKIVPVKLLELGEQDGLLEDKQVKQFVMDLTNPRQSAKLGRYPRTVITIADKPESSVMAFKKSTQTFSTTDSLYTIPVERTGNRETPATVHWRTNKASRFDISSPLKFAPGEAEKNILINPRTHPSPIIPEKFNLELLDPSNNAIIGKRKTTEVIVTDGRGDGKNQDFQKMEYVTQTATSPGGRLYSPANIKAVATGPKNIRLNWKP-SQNANGYKVKYWIYGDPEDKAKFMDVKTPQAELTNLDPYCDYEMRVCGYNALGDGNYSDIIQCQTLEDIPGEPGRLAFNVISPTVTQVSWAEPAEANGIITGYEVIYMPINEDKKPTGPPKKVMIDNPKKRMLLIENLQPSQTYCYKVRASNKVGWGPYREATINLASQPTRPMSIPIIPDIPIVDAEAGEEYDSYLMYSNEVLRSPTSSLRPSVTDLSDGSRWKHVKLVGSDLDLRKVSWKLPADIIPHRLSPSTDVSDN----------------------LAQTLAQDQFVNGKWEQNFLFPGGGGGSLSRNISSSSTTYSHSTPRTNVTNNSSTTTYISGKGGSTTHRYDVRDGGLLKEDVILRKRSENRHYTEGDGVRDSIVMGNLSGGLLDNLGVSSFSQTTSTSYSLSSRARTQSEDINDALLNLDSVLQESRFTPGVPATPSRLVFSALGHTALKVSWQEPHCESDVLGYCVLYQLINGGDVKRIEVNNPAQNSVLVQDLLPNQSYIFKVKAQSREGWGPEREGVITIESNVDPKSPLSPVPGSPFTLSTPSAPGPLIFTALRPDTLQLSWEKPRKPNGDILGYVVTCEQLHGGGDLRSFQVNG-NAATSLTVSDLKENMPYKFKVQAQTTQGFGPEREGIITIESQDGGSMSQYSSQS-VTKREVFNLPTEITHTSHTMFSEPFVSSDGMMMMSSRQITESGGSMTRQV--EMVQRGVMSSSTVTKRLERQYYEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q931-1", "uniprot_id": "A0A8M9Q931_DANRE", "id": "A0A8M9Q931-1", "name": "Integrin beta", "aln": "---------------------MMKAVLIALMVLLHCLGQKYTLGEEPVCQNQPSCSECIRS-PGCAWCTQMNFLKSGESNERRCDSPKSLKDRGCEDVRVINPGKHPL---DYVKNNDLSNDSYNVVQLKPQNVNIKLRVGVPYEFTVEFKRAQGYPIDLYYLMDLSYSMQDDLEQIKTLGQKILKKLKDITETVRIGFGSFVDKEMLPYVSQLPPRRKNPCPNRINT--CQKAFMFQNVLPLTSDGREFEREVSKQNISGNLDSPEAGLDAIMQAAVCKDKIKWG-NVTRILVYTSDDTFHMAGDGR--LGGAFLPHNGQCHFNDMGSYIG-KAYDYPSVGHVSRVLQDNNIQLIFAVTEEIYPAYKALSALIPQS-VVGVLKKDSSNVVDLISEAYGNLSSTLVLEQEGAPAELMVSYRSKCKDNQAANEWREKGECQGIKHEKITFQVRLN---ATACLKEPQIFRIKMQGISEEVKITVDTECQCDCGAAEKS----SEHCNHKGDLSCGMCSCDEGYLGQNCSCVQQNDTIKMLDSCRPNNR---------SLVCSGQGSCECGNCVCRN----EYSGKYCECDPDSCEKRNGVRCNGKGKCECGKCECRDRYTGSACECS--------PSQDKCKN-DWGLCSGQGECVCNRCHC--------------KPGVIGDYCSAFMDACELFKDCLACHLEGSGS-CHERCFNATVKHLEGTHELSCIYKHVSYSVELKASGEVNVKYADLP-----------HTVDKTAVIIGSSVSGIIITGIIIIIIYRLLLELYDYR---------------------EYQSFVKMQNQTQWKEAQNPLFKGATTTVMNPLHMQNEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZKE8-1", "uniprot_id": "A0A8I5ZKE8_RAT", "id": "A0A8I5ZKE8-1", "name": "Integrin beta", "aln": "-------------------MPRVPATLYACLLGLCALVPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEYFGNP-RSIISRCDLKANLIRNGCGGEIESPASSTHVLRNLPLSSKGSSAMGSDVIQMTPQEIAVSLRPGDQATFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGK--LGGLVQPHDGQCHLNEANEYTASDQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGT-TVEILHGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGLSYPGQRKCEGLKIGDTASFEVSVEAR-----SCPGRHTTQSFTLRPVGFRDSLQVEVAYNCTCG-CSAGLEPNSARCSGNGTYVCGLCECDPSYLGTRCECQEGENQSGYQNLCREAEG---------KPLCSGRGECSCNQCSCFESEFGRIYGPFCECDSFSCARNKGVLCSGHGECHCGECKCHVGYIGDNCNCS--------TDISTCRAKDGQICSDRGRCVCGQCQCTEPG----------AFGETCEKCPTCPDACSSKRDCVECSLLHQGKPDNQTCHHQCKDEVITWVDSIVKDDQEAVLCFYKTAKDCVMMFSYTELPN--GKSNLTVLREPECGSAPNAMTILLAVVGSILLVGMALLAIWKLLVTIHDRR--------------EFAKFQSERSRARYEMASNPLYRKPISTHTVDFAFNKFNKSYNGSVD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26012-1", "uniprot_id": "ITB8_HUMAN", "id": "P26012-1", "name": "Integrin beta-8", "aln": "MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLGQGEDNRCASSNAASCARCLALGPECGWCVQEDFISG-GSRSERCDIVSNLISKGCSVDSIEYPSVH-----VIIPTENEIN-----TQVTPGEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYN--LDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSK--LAGIVVPNDGNCHLKNN-VYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGT-IAGEIESKAANLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCRNVTSNDEVLFNVTVTMK-----KCDVTGGKNYAIIKPIGFNETAKIHIHRNCSCQCEDNRGPKGKCVDETFLDSKCFQCDENKCHFDEDQFSSES---------CKSHKD---------QPVCSGRGVCVCGKCSCHKIKLGKVYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPS-------AAAQHCVNSKGQVCSGRGTCVCGRCECTDPR----------SIGRFCEHCPTCYTACKENWNCMQCLHPHNLS-------------QAILDQCKTSCALMEQQHYVDQTSECFSSPSYLR-----------------------IFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIK--------------SSSDYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRCNF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PQQ8-1", "uniprot_id": "ITGBL_RAT", "id": "Q5PQQ8-1", "name": "Integrin beta-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MHPPGFKNFLLLVSSLFFIGLSAAPQSFSPSLRSLSGAPCRLSRAESERRCRAPGQPPGSALCHDRGRCECGVCICHVTEPGTYFGP---------------------------LCECHDWVCETYDGKTCAGHGTCDCG---------KCKCDVGWSGEACQYPTKCDLTKKISNQMCK-------NSQDVICSNAGTCHCGRCKCDNSDGHGLIYGKFCECDDRECIDDETEEICGGHGKCYCGNCY-CEAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGTCVCGECSCHDVDPTGDWGDIHGDT------------------CECDERDCRAVYDRYS---------------------------DDFCSGHGQCNCGRCDCRAGWYGKKCEHPKNCPLSAEESTRKCQGSS--------DLPCSGRGRCECGRCTCYPPGDSRVYGKTCECDDRRCEDLDGVVCGGRGTCSCGRCVCEKGWFGKLCQHPRKCNMTEEQSRSLCESADGTLCSGKGSCHCGKCICSGEE----------------WYISGEFCDCDDRDCDKHDGLICTGN------------------GICSCGNCECWDGWNGNACEIWLGTEYP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDV0-1", "uniprot_id": "ITGBL_MOUSE", "id": "Q8VDV0-1", "name": "Integrin beta-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MHPPGFRNFLLLVSSLLFIGLSAAPQSFLPSLRSLSGAPCRLSRAESERRCRAPGQPPGSALCHDRGRCECGVCICHVTEPGTYFGP---------------------------LCECHEWICETYDGKTCAGHGNCDCG---------KCKCDVGWSGEACQYPTKCDLTKKISNQMCK-------NSQDVICSNAGTCHCGRCKCDNSDGHGLIYGKFCECDDRECIDDETEEVCGGHGKCYCGNCY-CEAGWHGDKCEFQCDITPWESKRRCTSPDGKVCSNRGTCVCGECSCHDVDPTGDWGDIHGDT------------------CECDERDCRAVYDRYS---------------------------DDFCSGHGQCNCGRCDCRAGWYGKKCEHPRNCPLSAEESTKKCQGSS--------DLPCSGRGRCECGRCTCYPPGDSRVYGKTCECDDRRCEDLDGVVCGGHGMCSCGRCVCEKGWFGKLCQHLRKCNMTEEQSRSLCESADGTLCSGKGSCHCGKCICSGEE----------------WYISGEFCDCDDRDCDKHDGLICTGN------------------GICSCGNCECWDGWNGNACEIWLGTEYP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95965-1", "uniprot_id": "ITGBL_HUMAN", "id": "O95965-1", "name": "Integrin beta-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MRPPGFRNFLLLASSLLFAGLSAVPQSFSPSLRSWPGAACRLSRAESERRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGP---------------------------LCECHEWVCETYDGSTCAGHGKCDCG---------KCKCDQGWYGDACQYPTNCDLTKKKSNQMCK-------NSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCY-CKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDT------------------CECDERDCRAVYDRYS---------------------------DDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSS--------DLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEE----------------WYISGEFCDCDDRDCDKHDGLICTGN------------------GICSCGNCECWDGWNGNACEIWLGSEYP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27591-1", "uniprot_id": "ITBN_DROME", "id": "Q27591-1", "name": "Integrin beta-nu", "aln": "----------------MTSLGGRAFLWIYLVFLIAEISHSDADSIDDQCRHADSCERCLSAHLECAWCTDKEYQVG-----YRCLSRRQLLNYNCSETDIYENQPVLD--VLQDKPLKDYETSDQAVQVTPQRAYLKLVKGNTQRMKLSYRTARNNPLDLYVLMDLTWTMRDDKKTLEELGAQLSQTLKNLTGNYRLGFGSFADKPTLPMILPQHRENPCAAER----ATCEPTYGYRHQLSLTDDIPAFTSAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEQARKVVILVTDGFMHLAGDGL--LAGIIQRNDKQCHLNKAGEYTGSLNYDYPSLEEIYRELLRRKINVIFAVTEEVVSSYWELSALMKEISYVDILSADSSNILELIKKSYESLIKRTQFADNSPDFIDMAYYTDCGGQFPSLQKRNYCNNVTLGKQIDFYVDVTLKKYPDNQVYTHKIRVEETSLSEFMDLDVELQRPCPCQETPDPEN-EEGRFLCDYKGYLYCGMCECDEGWTGTYCNCPTDATNVTSNEALLQKCRQPFSDKSTSELVCSNHGDCDCGTCLCDPG----YTGPFCECR--ECLDCDEKLAD----CFCGQCVCKYGWSGSKCNCDG--------DTDACVGPTGEICSERGTCQCEECQCEEPYLGKFCEIDPEKDNKLCLFYEPCVTCLIEQKQGMGVCENLTEICSSLDRQETYPYNFVHELDPEQDQCLVRLVNKHGIQCDSFFVYQVIDHSN-------FLTIQAVDCEPPDYVALVGYISAFTLLIGLLIIFIILWYIRAKDAR----------------EYAKFEEDQKNSVRQENPIYRDPVGRYEVPKALSVKYDENPFAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . .* . . : . . . * : * * . . . : : . * . * : : :: * : . : : . : . :. : * * . **.:* * *. * * * *: * . * *.* * : * *: * :*. * * * .* * : ", "identical_positions": 34, "similar_positions": 44, "identity": "1.64%" }, { "cls_id": "homologset.agr.FB:FBgn0010397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLC1-1", "uniprot_id": "D3ZLC1_RAT", "id": "D3ZLC1-1", "name": "", "aln": "MSAPDPGSSAD---PPAAATAMASLPPRAG-SATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDKLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEAKKSAKKREGELTVARGRVKDLESLFHRSEAELAAALGDKHVLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENHCQSLQEELAFSKSVFEEEVQETRRRHERHLVEVDSSRQQEYDFKIAQALEELRSQHDEQVRLYRLELEQTYQAKLDNTKLISDQNDKAARAAREELKEARMRVESLSYQLSGLQKQASAAEDHIRELEEALAGERDKFRNMLDAKEQEMAEVRDAMQQQLAEYQELLDIKLALDMEICSYRKLLEGEEERLKLSPS--PSSRVTISLATSSSSSSSSSGVGMSLGRGRSKRQRLETEDTPGS-PSSASSVSSGS---RLAQQAGATGVVNIDEVDLEGRFVRLKNSSDKVSMGQGGRTGTPFLVAGGSKACLGCRINLWGTGGSRNRFWRVRTSPTSSHPSMSCEPARRSRCGQLAQGLHTAPHQPLCGRTRAAGGLGRTSAPSWSMRTARRWPCRLQSRHLSRGTRAGRRRK--RQRQSLVKRTFSTSRGTQGLPQGAAG-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21619-1", "uniprot_id": "LMNB2_MOUSE", "id": "P21619-1", "name": "Lamin-B2", "aln": "---------------------MASLPPHAG-PATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEDLRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQASAAENHIHELEEALAGERDKFRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPS--PSSRITISRATSSSSSS--SGVGMSVGQGRGKRRRLETEDTSGS-PSRASRVSSGS---RLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKR--QVLEGEDIAYKFTPKYVLRAGQTVTVWAAGAGATHSPPSTLVWKSQTNWG--PGESFRTALVS-------ADGEEVAVKAAKHSSVQGRENGEEEEEEEAEFGEEDLFHQQ--GDPR-------TTSRGCRLM-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03252-1", "uniprot_id": "LMNB2_HUMAN", "id": "Q03252-1", "name": "Lamin-B2", "aln": "MSPPSPGRRREQRRPRAAATMATPLPGRAGGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLKISEKEEVTTREVSGIKALYESELADARRVLDETARERARLQIEIGKLRAELDEVNKSAKKREGELTVAQGRVKDLESLFHRSEVELAAALSDKRGLESDVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELDFRKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYKLELEQTYQAKLDSAKLSSDQNDKAASAAREELKEARMRLESLSYQLSGLQKQASAAEDRIRELEEAMAGERDKFRKMLDAKEQEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYRKLLEGEEERLKLSPS--PSSRVTVSRATSSSSGS----LSATGRLGRSKRKRLEVEEPLGSGPSVLGTGTGGSGGFHLAQQASASGSVSIEEIDLEGKFVQLKNNSDKDQSLGNWRIKR--QVLEGEEIAYKFTPKYILRAGQMVTVWAAGAGVAHSPPSTLVWKGQSSWG--TGESFRTVLVN-------ADGEEVAMRTVKKSSVMRENENGEEEEEEAEFGEEDLFHQQ--GDPR-------TTSRGCYVM-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70615-1", "uniprot_id": "LMNB1_RAT", "id": "P70615-1", "name": "Lamin-B1", "aln": "-------------MATATPVQQ-RAGSRASAPATPFSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPS--PSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----ISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIR---KIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWG--TGEDVKVVLKN-------SQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLEEERFHQQ--GTPR-------ASNKSCAIM-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14733-1", "uniprot_id": "LMNB1_MOUSE", "id": "P14733-1", "name": "Lamin-B1", "aln": "-------------MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPS--PSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----ISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIR---KIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWG--TGEDVKVILKN-------SQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVAVEEERFHQQ--GAPR-------ASNKSCAIM-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20700-1", "uniprot_id": "LMNB1_HUMAN", "id": "P20700-1", "name": "Lamin-B1", "aln": "-------------MATATPVPP-RMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPS--PSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----ISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIR---KIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWG--TGEDVKVILKN-------SQGEEVAQRSTVFKTTIPEEEEEEEE-AAGVVVEEELFHQQ--GTPR-------ASNRSCAIM-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHC4-1", "uniprot_id": "F1QHC4_DANRE", "id": "F1QHC4-1", "name": "", "aln": "-------------MASAACTPAGQQSLSRGTSSTPLSPARISRLQEKEELQQLNDRLAAYIDTVRSLESENSVLQIQIREREDVRNRELTGLRTLYETELADARKALDDTARERARLQIELGKIKSEQEQLQHTYAKKDADLTSSQNRLKDVEALLNAKEAALNTAVSERKTLENTLSDLQIRVQELEGGLISAKKQLSDETLLRVDLENRCQSLMEELEFRKNMFEEEIKDTRRRHETRLVEVDSGRQMEYEFKLAQALTDMRQQHDEQVKLYKEEMEQTYVSKLENIRLSSEMNSSSASMAREELRESTLRVESLAGQLANLQKEARAWQDRINELEGALSHEKDLSRRLLAEKEREIAEIRAKMQQQLDEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPS--PSSRVTVSRASSSRSVR----------TTRGKRKRVDVEESEAS--------SSVS----IAHSASATGNVSIDELDVDGKFIRLHNNSEQDQPMAGFQLTR---TIGEVTATYKFTAKYNLKAGQKVTIWASNAGISSNPPADLIWKNQPSWG--TGENIKVALLS-------PAGEEVAVRSTVFKTAVEDEDDDEEEEKEAEVIEEHFYHQQ--GDPR-------AAKRGCLIM-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48679-1", "uniprot_id": "LMNA_RAT", "id": "P48679-1", "name": "Prelamin-A/C", "aln": "---------------METPSQRRPTRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPS--PTSQRSRGRASSHSSQS-------QGGGSVTKKRKLESSESRSS----------------FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKR--QNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWG--CGTSLRTALIN-------ATGEEVAMRKLVRSLTMVEDNDDEEEDGDELLHHHRGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKA-ASGSGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSSQNCSIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48678-1", "uniprot_id": "LMNA_MOUSE", "id": "P48678-1", "name": "Prelamin-A/C", "aln": "---------------METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPS--PTSQRSRGRASSHSSQS-------QGGGSVTKKRKLESSESRSS----------------FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRR--QNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWG--CGSSLRTALIN-------STGEEVAMRKLVRSLTMVEDNEDDDEDGEELLHHHRGSHCSGSGDPAEYNLRSRTVLCGTCGQPADKA-AGGAGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRSQSSQNCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02545-1", "uniprot_id": "LMNA_HUMAN", "id": "P02545-1", "name": "Prelamin-A/C", "aln": "---------------METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPS--PTSQRSRGRASSHSSQT-------QGGGSVTKKRKLESTESRSS----------------FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKR--QNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWG--CGNSLRTALIN-------STGEEVAMRKLVRSVTVVED--DEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03427-1", "uniprot_id": "LMNA_DROME", "id": "Q03427-1", "name": "Lamin-C", "aln": "MSARRVTLNTRVSRASTSTPVGGASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTR---IAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMKKKWPVAN----SMRSVLAN-------ADKEDVASYDRVRANVSSHTSRHRSSGTPSTGFTLGSGAGS-------------TGVRSLFSLLF---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::* **:* :* ****:*:.****** *** :* ** ** * .: ::. ** :.::: ** **. **: **..*:*:*:*:::: : * .: *: : :. . : * : : ::.::: :* :* . . . :*** * * :** **: *:: *:* * ..:. :*: :*: ::: .: *:*. . ::: :: ::* ::* *:: *:. : *:* * :::. : :: . * : :::.* :* *:. . ::.:** : *:: .. : * *: .:* * :** :*: *:*:*::**:** :* *** ***.**.:... *:: . * : . .. . : : :.* : : * * :*:*::*:*.. : . . .* .* :. : . * : ..: . . . . : . ", "identical_positions": 110, "similar_positions": 174, "identity": "15.34%" }, { "cls_id": "homologset.agr.FB:FBgn0010398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE86-1", "uniprot_id": "D3ZE86_RAT", "id": "D3ZE86-1", "name": "Leucine-rich repeat protein 1", "aln": "MRLPCEVEVRSCHLPTLGLKSRGKGVRAVVSLCQAPSKNELQPGARTETSGCACLLVSTMKDRQGTRYRLRENIEQLFTKFVDEGKATVRLKEPPVDICLSKANPGNLKTFLSAMRLAHRGS-DVNTPLSTLKPVKTSEFEKFKTKMIITSKKDYPLSKNFPYSLEHLQASHCRLARVDMRMLCLKSLTKLDLSHNCIKKLPATIGDLTHLQELNLSDNQLESFS--VPLCKSTLQKSLQSLDLSKNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGRLTNLRFLSAARNKLRNLPCEFKMLSLEYLDLFGNTFEKP-------EVLPIINLQVPLTLLEACEQAVLSYRIPYGPDIIPYHLCQDLDTAKTCVCGRFCLQSFIQGTTTMNLHSLAHTVVLIDTMGRMEAPIISYFCSLTCFVNSSDMLK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YY91-1", "uniprot_id": "LLR1_MOUSE", "id": "D3YY91-1", "name": "Leucine-rich repeat protein 1", "aln": "MRLPCEVEVRSCHLPTLGLKSRGKGVRAVVSLCQAPGRNELQPEARAEPGGHACLLVSTMKDRQGTSYKLRENIEQLFTKFVDEGKATVRLKEPPVDICLSKANPGNLKTLLSAMRLAHRGC-DVNTPLSTLKPVKTSEFEKYKTKMVITSKKDYPLSKNFPYFLEHLQASYCSLARVDMRMLCLKNLTKLDLSHNCIKKLPATIGDLTHLQELNLNDNQLETFS--VPLCTSTLQKSLHSLDLSKNKIKALPVQFCQFRELTNLNLNDNELIHLPFKIGQLTNLRFLSAARNKLRNLPSEFKMLSLEYLDLFGNTFEKP-------EVIPIIKLQVPLTLLESCEQAVLFYRIPYGPDIIPYHLCQDLDTAKTCVCGRFCLQSFIQGTTTMNLHSVAHTVVLVDSMGRTEAPVVSYFCSLTCFVKSSDMLN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L50-1", "uniprot_id": "LLR1_HUMAN", "id": "Q96L50-1", "name": "Leucine-rich repeat protein 1", "aln": "MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRS--QPPVR------AFLLISTLKDKRGTRYELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGC-NVDTPVSTLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFS--VALCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQP-------KVLPVIKLQAPLTLLESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYVNSSDMLK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKU0-1", "uniprot_id": "Q9VKU0_DROME", "id": "Q9VKU0-1", "name": "", "aln": "MKILCEVQVVNRATQTN---KTPRPVKSTLAIGYKQSARDANGNTKK----ELEMVLFSGQNKTGNRYKVKDNIHVVHTKFVLDGKTTIGFIQPP-DNLLIKCDPIQLKGFLQTLKLGMDGKDAINLRLNINAATAIPQKAQPQVRMVISKRSEYPIKG-FPRTLKSLTINNSQLVKLSFEICTLRNLTKLDVSGNKLTKIPSELGRLP-LTSLHLGNNLLGTQNDWCWLRGTKLCQSLGELDLSGNGLTYFPPPLVKFESLVSLNLNNNLLSRLPFAIRRMKALRKLYVCSNELESLPSAVEDLRIDLLDVWGNCFKEFNADAAQQMYLQKAASNSPQPLWLLGARAVDKYMLPLSAGSIPAVLIDLIREAPRCPCGELCYAQRKEDLFQRVVQPKFITVKNLTYSREHQIYADVVLCDSRCSASAELKLLFNIIFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ***:* . : . : *::.::: . : .: ::: : ::: *. *.:::**. ..**** :**:*: : :** * * *. . .** :*.:::*. * :: :. .. .: : :.:*:*:.:.:**:. ** *: * . . *.::.:.: *:.* ***:* * :.*:*: :* * * .*:*.:* * : . * :.* :** .**** * :. :* : ::..* .*:*::* * ::* * :: ** * .. *:* **. .. * :: **::** *:: : : * .* ::: :* .. ** * : : * * **.:* . :. ::. ** : : :*. * ..:. * ", "identical_positions": 98, "similar_positions": 149, "identity": "22.37%" }, { "cls_id": "homologset.agr.FB:FBgn0010399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35439-1", "uniprot_id": "NMDZ1_RAT", "id": "P35439-1", "name": "Glutamate receptor ionotropic, NMDA 1", "aln": "------------MSTMHLLTFALLFSCSFARAACDPKIVNIGAVLSTRKHEQMFREAVNQAN--KRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESK---------------------AEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVG---IYNGTHVIPN----DRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNS----NKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVN-SEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRY----QECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQD------------------------------RKSGRAEPDPKKKATFRAITSTLASSFKRRR--------SSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35438-1", "uniprot_id": "NMDZ1_MOUSE", "id": "P35438-1", "name": "Glutamate receptor ionotropic, NMDA 1", "aln": "------------MSTMHLLTFALLFSCSFARAACDPKIVNIGAVLSTRKHEQMFREAVNQAN--KRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESK---------------------AEKVLQFDPGTKNVTALLMEARDLEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVG---IYNGTHVIPN----DRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCVDLLIKLARTMNFTYEVHLVADGKFGTQERVNNS----NKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVN-SEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRY----QECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQD------------------------------RKSGRAEPDPKKKATFRAITSTLASSFKRRR--------SSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05586-1", "uniprot_id": "NMDZ1_HUMAN", "id": "Q05586-1", "name": "Glutamate receptor ionotropic, NMDA 1", "aln": "------------MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQAN--KRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAAQKRLETLLEERESK---------------------AEKVLQFDPGTKNVTALLMEAKELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVG---IYNGTHVIPN----DRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNS----NKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVN-SEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRY----QECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQD------------------------------RKSGRAEPDPKKKATFRAITSTLASSFKRRR--------SSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IA45-1", "uniprot_id": "A0AC58IA45_DANRE", "id": "A0AC58IA45-1", "name": "Glutamate receptor", "aln": "---------------MRLLLLAALFSCSCVRGGCEPKIVNIGAVLSQKRYEQVFKDAVTQAN--QVYGRDKFKLTAISVTHKANAIQMALSVCEDLISSQVYAILVSHPPQSNDHLTPTPVSYTAGFYRIPVVGLTTRMSIYSDKSIHLSFLRTVPPYSHQAHVWFDMMREFRWNHIILIVSDDHEGRAAQKRLETLLEERETKNKKRNYENQDQLSYDNKRGPKAEKVLQFNQETN-LTALLLEAKELEARVIILSASEEDAAAVYKTARFLNMTGSGYVWLVGEREMSGKALSEAPDGLIGLQLINGKNESAHISDAVAVVAQSIQELFEKENITEPPRGCVGNTNIWKTGPLFKRVLMSSKYPEGLTGRVEFNDDGDRKYAHYSILNYQKSRLIQVG---IYNGTQVVMNK---QRKIIWPGGETERPRGFQMSTRLKIVTIHQEPFVYVKPTTLEGTCKEEYTPNGVLIKKVICTGPNETIPGRP--IVPQCCYGFCIDLLIKLALTMNFTYEVHLVADGKFGTQERVNNS----NKKEWNGMMGELLGGLADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVN-SEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLAILSSHENGFMEDLDKTWVRY----QECDSRSNAPATLTFENMAGVFMLVAGGIAAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDNKESSGSQAVGAAGTPSLPSSSVE--TQDDRKSGRADSDPKKKPSFRSISTTLASSIKRRR--------SSK---------------DTQYPPTDIT---GQLNLSDPSVSTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24418-1", "uniprot_id": "NMDA1_DROME", "id": "Q24418-1", "name": "Glutamate [NMDA] receptor subunit 1", "aln": "MAMAEFVFCRPLFGLAIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIKHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSG-DLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVR---------------ATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSN---NTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKS-RNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRMGDD-----EFRCEPDERPCPLFNNSDAT-------ANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRRYPRLGQRLGPERAWPGDAADVLRIRRPYELGNPGQSPKVMAANQPGMPMPMLGKTRPQQSVLPPRYSPGYTSDVSHLVV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* : :.. .. :*. ***.*** *: * ::.: * : : *. :: . *.*: .:.**:.**..:***::*** .. .::*:.****:*** ***:*:::* : :***.**:********* **: **::*: : :.::*:: *.* :*** *::* : . .* :::*: : .* *:: : ::** :: ** :** .::: * ****.*:**:* *: : .: :***::**** :.:.:..** *:* *:*.:::*::.:*.*::.*:.* ..: *::* : : * * : * **:* *:::*** :* *.::* :: : :* *:. :. . : :***** : .:*.* :.*:*:::**.::*****: : *: : : ...: * ** *:*:****:*: :****:: * .**:** **: :***.*::***:. *********** ***:************:*** ** *** **:***..***:** :******::**************:. *:.:**.**.****:**:************:*******:**************************:**: :::****.****. ::: **** ****:*********.*** ** :** :* :*** *:..** ******: **:***:.*:***:**** ***:***::*.***.: *:*:**. **.****.*** *: : *:*: .::* ** ::******:**. **..*: **:**: **:*: ::*::::* *.: ** .::. .. * :: . *: . *. :: ** .* .. * : . . ", "identical_positions": 404, "similar_positions": 285, "identity": "39.26%" }, { "cls_id": "homologset.agr.FB:FBgn0010406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C0HKG5-1", "uniprot_id": "RNT2A_MOUSE", "id": "C0HKG5-1", "name": "Ribonuclease T2-A", "aln": "-MAPAEARGALPGWISVLGWGLALCSLCGAGPLWSG------------------------------------SHEWKKLILTQHWPPTVCKEVN--------SCQDSLDYWTIHGLWPDRAED-----CNQSWHFN-------LDEIKDLLRDMKIYWPDVIH--------RSSNRSQFWKHEWVKHGTCAAQV-------------DALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSI-NYYQLADFKDALTRIY-GVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCTEPGEQLSSRQEAWLAM---EAS-THGMMVCED-GPIFYPPPTKTQH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCH6-1", "uniprot_id": "D3ZCH6_RAT", "id": "D3ZCH6-1", "name": "", "aln": "---MAEARGALPGWVSVLGWGLALCCLCGAGPLWSG------------------------------------SHEWKKLILTQHWPPTVCKEVN--------RCRDSLDYWTIHGLWPDRAED-----CNHSWHFN-------LNEIKDLLRDMKIYWPDVIH--------PSSNRSQFWKHEWDKHGTCAAQV-------------DALNSERKYFGKSLDLYKQIDLNSVLQKFEIKPSI-NYYQLADFKDALTRIY-GVVPKIQCLMPEQGENVQTIGQIELCFTKEDFHLRNCTEPEEQPSSGQEARLAR---EAS-THGMMVCED-GPIFYPPP-KSQH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00584-1", "uniprot_id": "RNT2_HUMAN", "id": "O00584-1", "name": "Ribonuclease T2", "aln": "-MRPAALRGALLGCL-----CLALLCLGGADKRLRD------------------------------------NHEWKKLIMVQHWPETVCEKIQN-------DCRDPPDYWTIHGLWPDKSEG-----CNRSWPFN-------LEEIKDLLPEMRAYWPDVIH--------SFPNRSRFWKHEWEKHGTCAAQV-------------DALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSI-NYYQVADFKDALARVY-GVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLAN---GAAESRGLRVCED-GPVFYPPPKKTKH---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8XY56-1", "uniprot_id": "RNT2_DANRE", "id": "B8XY56-1", "name": "Ribonuclease T2", "aln": "------MRFIAFAVI------FSAVYLCSS-AFTHP------------------------------------RGEWTKLILTQHWPQTFCKMEH---------CKTDFSYWTLHGLWPNTGVR-----CNTSWHFN-------ASLIEDILPEMEKFWPDLLE--------PSS--PKFWNYEWTKHGTCAAKS-------------ESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPSE-KHYTLEDVEEAITSAY-GVKPKIQCVHPGQGGQVQILGQIEICVDR-DFQLMGCEKSSEDTWSNDLPTVPV---SGQ--SGLSVCDHSMPVYYPPVQA------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSC3-1", "uniprot_id": "Q9VSC3_DROME", "id": "Q9VSC3-1", "name": "", "aln": "MQSQRFLFVAILACFLVTIKSTPLSDISYSDESTSVNEKTQKRPDDDSEFDGFPFREDDDSLQDSSREMSVQDHNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQMGPNFCNNSANFD-------PSKLNPIEDRLETFWPDLKG--------MDS-TEWLWKHEWQKHGTCAMLV-------------EELDNELKYFEQGLTWREEYIMSRILDASDIHPD--SNNTVAAINNAIVKAL-GKNPSIHCLYDGKHG-ISYLSEIRICFSK-SLELIDCDGIKQG--DAVPVGVPG---GTIITNCHIGSLVHYPSLVPPLQRKSHWKLPLVNVYKLLQFLMWFTL-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB13A9V5-1", "uniprot_id": "A0AB13A9V5_DANRE", "id": "A0AB13A9V5-1", "name": "", "aln": "-MTYNKHILWAFTAALATGWVLSNDEGCYYGTVMKH------------------------------------SCNWTCMLLTLQWPGSFCIGLTN---KTICKIPLTIQNWTIHGLWPMHTGH-----CCNCWPIF-------HSHLQEIEPELTQLWPSLIK--------GKH-FFNFWREEWIKHGTCAGCD-------------GAMGSPLLYFQAAVKLRKLFDINSVLESSGIKASCEVSYKYDDISKALTSLL-GDNFDLQCVTDSKGREAWIQLKIHLSRNQ----TIGCPTEKQDEAFYNLAWYKS---PGH-PCPKNTTIFFVPINYDNPHEPCN---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02933-1", "uniprot_id": "RNY1_YEAST", "id": "Q02933-1", "name": "Ribonuclease T2-like", "aln": "-MLLKNLHSLLQLPIFSNGADKGIEPNCPINIPLSCSNKTDIDN------------------------SCCFEYPGGIFLQTQFWNYFPSKNDLN--ETELVKELGPLDSFTIHGLWPDNCHGGYQQFCNRSLQIDDVYYLLHDKKFNNNDTSLQISGEKLLEYLDLYWKSNNGNHESLWIHEFNKHGTCISTIRPECYTEWGANSVDRKRAVYDYFRITYNLFKKLDTFSTLEKNNIVPSVDNSYSLEQIEAALSKEFEGKKVFIGCDRHNSLNEVWYYNHLKGSLLSEMFVPMDSLAIRTNCKKDGIKFFPKGYVPTFRRRPNKGARYRGVVRLSNINNGDQMQGFLIKNGHWMSQGTPANYELIKSPYGNYYLRTNQGFCDIISSSSNELVCKFRNIKDAGQFDFDPTKGGDGYIGYSGNYNWGGDTYPRRRNQSPIFSVDDEQNSKKYKFKLKFIKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * . . :*:**:** * . : . :: : .: :* *: ***** ** . * * .. .. *: * : * . .:. . .. ", "identical_positions": 21, "similar_positions": 32, "identity": "4.56%" }, { "cls_id": "homologset.agr.FB:FBgn0010407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01973-1", "uniprot_id": "ROR1_HUMAN", "id": "Q01973-1", "name": "Inactive tyrosine-protein kinase transmembrane receptor ROR1", "aln": "-------MHRPRRRGTRPPLLALLAALLLAARG----AAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP-PTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLD-ENFKSDLCDIPACDSKDSK----EKNKMEILYILVPSVAIPLAIALLFFFICVCRNNQK-SSSAPVQRQPKHVRGQNVEMSMLN-------------AYKPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYLPG-MDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRYPNYMFPSQGIT-PQGQ-IAGFIGPPIPQNQRFIPINGYPIPPGYAAFPAAHYQPTGPPRVI-QHCPP---PKSRSPSSASGSTSTGHVTSLPSSGSNQEANIPLLPHMSIPNHPGGMGITVFGNKSQKPYKIDSKQASLLGDANIHGHTES-MISAEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z139-1", "uniprot_id": "ROR1_MOUSE", "id": "Q9Z139-1", "name": "Inactive tyrosine-protein kinase transmembrane receptor ROR1", "aln": "-------MHRPRRRGTRPPPLALLAALLLAARG----ADAQETELSVSAELVPTSSWNTSSEIDKGSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPSIRWFKNDAPVVQEPRRISFRATNYGSRLRIRNLDTTDTGYFQCVATNGKKVVSTTGVLFVKFGPP-PTASPGSSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEVLENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHSFTALRFPELNGGHSYCRNPGNQKEAPWCFTLD-ENFKSDLCDIPACDSKDSK----EKNKMEILYILVPSVAIPLAIAFLFFFICVCRNNQK-SSSPPVQRQPKPVRGQNVEMSMLN-------------AYKPKSKAKELPLSAVRFMEELGECTFGKIYKGHLYLPG-MDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRFPNYMFPSQGIT-PQGQ-IAGFIGPAIPQNQRFIPINGYPIPPGYAAFPAAHYQPAGPPRVI-QHCPP---PKSRSPSSASGSTSTGHVASLPSSGSNQEANVPLLPHMSIPNHPGGMGITVFGNKSQKPYKIDSKQSSLLGDSHIHGHTES-MISAEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQX3-1", "uniprot_id": "A0A8I5ZQX3_RAT", "id": "A0A8I5ZQX3-1", "name": "", "aln": "--------------------------------------------------------------------------MNNITTSLGQTAELHCKVSGNPPPNIRWFKNDAPVVQEPRRISFRATNYGSRLRIRNLDTTDTGYFQCVATSGKKVVSTTGVLFVKFGKQ-PSTG-LATDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEVLENVLCHTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHSFTALRFPELNGGHSYCRNPGNQKEAPWCFTLD-ENFKSDLCDIPACDSKDSK----EKNKMEILYILVPSVAIPLAIAFLFFFICVCRNNQK-SPSPPVQRQPKPVRGQNVEMSMLN-------------AYKPKSKAKELPLSAVRFMEELGECTFGKIYKGHLYLPG-MDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRFPNYMFPSQGIP-PQGQ-IAGFIGPAIPQNQRFIPINGYPIPPGYAAFPAAHYQPAGPPRVI-QHCPP---PKSRSPSSASGSTSTGHVASLPSSGSNQEANVPLLPHMSIPNHPGGMGITVFGNKSQKPYKIDSKQPSLLGDSNIHGHTES-MISAEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M2Z2-1", "uniprot_id": "A0ABK0M2Z2_RAT", "id": "A0ABK0M2Z2-1", "name": "", "aln": "MTKLPKHQLRLVVGKPFPGKTRLHIVTVFWEDFGCQNHSGEVEDSEAIDTLGQLDGPDSPLPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRVIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGLKTITATGVLYVRLGPT-HSPNHNFQDDDQEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLENDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP-AERLGRYHQCYNGSGTDYRGMASTTKSGHQCQPWALQHPHSHRLSSTEFPELGGGHAYCRNPGGQMEGPWCFTQN-KNVRVELCDVPPCSPRD-------GSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLIS-------------QHK-QAKLKEISLSTVRFMEELGEDRFGKVYKGHLFGPAPGEPTQVVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMVFSYCCHGDLHEFLVMRSPHSDVG-STDDDRTVKSALEPPDFVHVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREVYSADYYKLMGNSLLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSGRPRFKDIHGRLRSWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYMAPKQKAQPFPQPQFIPMKGQIRPLVPPAQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSVADRAALLSEGTEDVQNMPEDVAQSPVQEAEEEEEGSVPETELLGDSDTLQVNEA-HVHLEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z138-1", "uniprot_id": "ROR2_MOUSE", "id": "Q9Z138-1", "name": "Tyrosine-protein kinase transmembrane receptor ROR2", "aln": "---MARGWVRPSRVPLCARAVWTAAALLLWTPW----TAGEVEDSEAIDTLGQPDGPDSPLPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRVIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGLKTITATGVLYVRLGPT-HSPNHNFQDDDQEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTQLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLENDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP-AERLGRYHQCYNGSGADYRGMASTTKSGHQCQPWALQHPHSHRLSSTEFPELGGGHAYCRNPGGQVEGPWCFTQN-KNVRVELCDVPPCSPRD-------GSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLIS-------------QHK-QAKLKEISLSTVRFMEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVG-STDDDRTVKSALEPPDFVHVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREVYSADYYKLMGNSLLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRSWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYMAPKQKAQPFPQPQFIPMKGQIRPLVPPAQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSVADRAALLSEGTEDAQNIAEDVAQSPVQEAEEEEEGSVPETELLGDNDTLQVTEAAHVQLEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01974-1", "uniprot_id": "ROR2_HUMAN", "id": "Q01974-1", "name": "Tyrosine-protein kinase transmembrane receptor ROR2", "aln": "---MARGSALPRRPLLCIPAVWAAAALLLSVSR----TSGEVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPT-HSPNHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP-AERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQN-KNVRMELCDVPSCSPRD-------SSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLIN-------------QHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVG-STDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEA-QVQLEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCE4-1", "uniprot_id": "E7FCE4_DANRE", "id": "E7FCE4-1", "name": "", "aln": "-----MFPVRMYHILRITTGAHLVATFIFFATFAY--AEADVNLFESEEIEALAEAQSGGLPTPEGYYLEFLEQPNNITIVQGQTATLHCKVAGHPRPSIRWLKNDAPVVQEQGRVSIRKTEAGSKLRIQDLDTTDTGYYQCVATNSIKVISATGVLYVRLGNTGQSPAHGAEDSTHEKGFCQPYRGIACARFIGNRSIYVESLQMQGESENRITAAFTMIGTSTQLSDQCSEFAIPSFCYYVFPLCEEGTRGPRRRQLCRDECEALENDLCNAEYTIARSNPLILMQLELPVCSLLPHPGSPDASSCIRIGLP-PQYSPPDHSCYNESGGNYKGTVSVTKSGFQCQPWSAQYPHSHHLSPIEYPQLRGGHNFCRNPGGQMESPWCFTLD-PNVRVDLCDIPPCNPPE-------KMKKELLYILIPSVATPLVFACLFFLICMCRNKQKESVDTPTRRQLTASPSQEMELPLLN-------------QHKHQAKLRELNLSAVRFMEELGEDRFGKVYKGHLYGTAPGEQTQVVAIKTVKDKDEGPLREEFRHEAMLRSRLQHPNIVCLLGVITKEQPMSMIFSYSGQGDLHEFLVMRSPHSDVG-SSDDDKTVKSTLEQADFLHIVTQVAAGMEYLSSHHVVHKDLAARNILVCDKLNVKILDLGLFREVYSADYYKLMGASPFPIRWMSPEAILYGKFSTDSDIWSYGVVLWEIFSYGLQPYCGYSNQDVIEMVRNRQVLSCPDDCPAWIYTMMLECWNEFPSRRPRFKDIHARLRTWESLSNYNSSAQTSGASNTTQTSSLSTSPVSNISNARYVSPK-KSSPFPQPQFVSMKGQMRPMVPP-QLYIPVNGYQPMPAY-PYLQNFYPMQIPMQMPPQQMHPQMVAKAGSHHSGSGSTSTGYVTTAPSNGSGTDKVALMNE---DLKATEDDFADGASQKGLHHEDLSVPETELLGDNDSPHTEDN-EINSDA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24488-1", "uniprot_id": "ROR1_DROME", "id": "Q24488-1", "name": "Tyrosine-protein kinase transmembrane receptor Ror", "aln": "-------------------------------------------------------------MNKYSAFIVCISLVLLFTKKDVGSHNVDSRIYGFQQSSGICHIYNGTICR--DVLSNAHVFVSPNLTMNDLEERLKAAYGVIKESKDMNANCRMYALPSLCFS----SMPICRTPERTNLLYFANVATNAKQLKNVSIRRKRTKSKDIKNISIFKKKSTIYEDVFSTDISSKYPP-------------TRESENLKRICREECELLENELCQKEYAIAKRHPVIGM-VGVEDCQKLP-----QHKDCLSLGIT--IEVDKTENCYWEDGSTYRGVANVSASGKPCLRWSWLMKEIS-----DFPELIG-QNYCRNPGSVENSPWCFVDSSRERIIELCDIPKCADKIWIAIVGTTAAIILIFIIIFAIILFKRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQDAGRGNLGNLSDHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPN--KTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP------------TEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTWHEGHFKASNPEM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : :..:: * .. :..: : : . ...* :.:*: .. : : . . : .. .: . : *: : * :: . : :. : * : * . :* .*::. . : :**:*** **. **. ** :*: :*:* * : : *. ** : .*: :*:. ..** * *:* ...: ** * * . :*:* * : :*****. :.****. . : :***:* * :::*:: :: : :.: : :* :. * . : .*: :. : : ..: *. *.*:***** ***:***:* . . : ****::*: . :*::* * : *:* *:**:**.: :.:* .*:*.* :*******: .** * .:*. :*:::. *:: **::**:*. **:***:** *: : * *:* *:** *::*::***:: . * :*:***..*:::****: :**:**:******::*:*:*** *:***:*::::*.**:*...::**. :*::* ***:* . ** *.** **::* *.. ", "identical_positions": 182, "similar_positions": 213, "identity": "18.65%" }, { "cls_id": "homologset.agr.FB:FBgn0010408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29314-1", "uniprot_id": "RS9_RAT", "id": "P29314-1", "name": "Small ribosomal subunit protein uS4", "aln": "MPVARS-WVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWN5-1", "uniprot_id": "RS9_MOUSE", "id": "Q6ZWN5-1", "name": "Small ribosomal subunit protein uS4", "aln": "MPVARS-WVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46781-1", "uniprot_id": "RS9_HUMAN", "id": "P46781-1", "name": "Small ribosomal subunit protein uS4", "aln": "MPVARS-WVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZV50-1", "uniprot_id": "D3ZV50_RAT", "id": "D3ZV50-1", "name": "Small ribosomal subunit protein uS4", "aln": "MLVARS-WVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55935-1", "uniprot_id": "RS9_DROME", "id": "P55935-1", "name": "Small ribosomal subunit protein uS4", "aln": "MVNGRIPSVFSKTYVTPRRPYEKARLDQELKIIGEYGLRNKREVWRVKYALAKIRKAARELLTLDEKDEKRLFQGNALLRRLVRIGVLDESRMKLDYVLGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNLKKNQGGGGGAAEEEED----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O13516-1", "uniprot_id": "RS9A_YEAST", "id": "O13516-1", "name": "Small ribosomal subunit protein uS4A", "aln": "MPRAPR--TYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAADEADEADEE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05755-1", "uniprot_id": "RS9B_YEAST", "id": "P05755-1", "name": "Small ribosomal subunit protein uS4B", "aln": "MPRAPR--TYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *** **:**:*.:*** ***: **:**:**:*::*:.: *:***:***:*** **** :***:****:*****: **.*.: ****:*.**:************:** ****:***:*** **** * **:******:* ***.*****: **:**.***** *:* : ..* . :* .: ", "identical_positions": 118, "similar_positions": 45, "identity": "59.3%" }, { "cls_id": "homologset.agr.FB:FBgn0010409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62718-1", "uniprot_id": "RL18A_RAT", "id": "P62718-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-AGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62717-1", "uniprot_id": "RL18A_MOUSE", "id": "P62717-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-AGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02543-1", "uniprot_id": "RL18A_HUMAN", "id": "Q02543-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIA-ASKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWJ4-1", "uniprot_id": "RL18A_DANRE", "id": "Q7ZWJ4-1", "name": "Large ribosomal subunit protein eL20", "aln": "MKASGTLREYKVVGRLLPSVKNPAPPLYRMRIFAPNHVVAKSRFWYFVSQLRKMKKASGEIVYCGLVFEKSPLKVKNFGIWLRYDSRSGTHNMYREYRDLTTSGAVTQCYRDMGARHRARAHAIQIMKVQVIA-ANKCRRPAIKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41093-1", "uniprot_id": "RL18A_DROME", "id": "P41093-1", "name": "Large ribosomal subunit protein eL20", "aln": "MRAKGLLKEYEVVGRKLPSEKEPQTPLYKMRIFAPDNIVAKSRFWYFLRQLKKFKKTTGEIVSIKQVYETSPVKIKNFGIWLRYDSRSGTHNMYREYRDLTVGGAVTQCYRDMGARHRARAHSIQIIKVDSIP-AAKTRRVHVKQFHDSKIKFPLVQRVHHKGNRKLFSFRKPRTYFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX24-1", "uniprot_id": "RL20B_YEAST", "id": "P0CX24-1", "name": "Large ribosomal subunit protein eL20B", "aln": "---MAHFKEYQVIGRRLPTESVPEPKLFRMRIFASNEVIAKSRYWYFLQKLHKVKKASGEIVSINQINEAHPTKVKNFGVWVRYDSRSGTHNMYKEIRDVSRVAAVETLYQDMAARHRARFRSIHILKVAEIEKTADVKRQYVKQFLTKDLKFPLPHRVQKS--TKTFSYKRPSTFY-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX23-1", "uniprot_id": "RL20A_YEAST", "id": "P0CX23-1", "name": "Large ribosomal subunit protein eL20A", "aln": "---MAHFKEYQVIGRRLPTESVPEPKLFRMRIFASNEVIAKSRYWYFLQKLHKVKKASGEIVSINQINEAHPTKVKNFGVWVRYDSRSGTHNMYKEIRDVSRVAAVETLYQDMAARHRARFRSIHILKVAEIEKTADVKRQYVKQFLTKDLKFPLPHRVQKS--TKTFSYKRPSTFY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::**:*:** **: . . *::*****.:.::****:***: :*:*.**::**** : * * ::****:*:************:* **:: .** *:**.****** ::*:*:** * : . :* :*** ..:**** :** : *: ::* *:: ", "identical_positions": 79, "similar_positions": 51, "identity": "44.38%" }, { "cls_id": "homologset.agr.FB:FBgn0010411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CX56-1", "uniprot_id": "RS18B_YEAST", "id": "P0CX56-1", "name": "Small ribosomal subunit protein uS13B", "aln": "MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALT-------------------------------------------------------TIKG----------------------VGRRYSNLVCK---KADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITD---------------------GKDYHTLANNVESKLR-DDLERLKKIRAHRGIR-----------------HFWG---------------------LRVRG------QHTKTTGRR-RA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX55-1", "uniprot_id": "RS18A_YEAST", "id": "P0CX55-1", "name": "Small ribosomal subunit protein uS13A", "aln": "MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALT-------------------------------------------------------TIKG----------------------VGRRYSNLVCK---KADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITD---------------------GKDYHTLANNVESKLR-DDLERLKKIRAHRGIR-----------------HFWG---------------------LRVRG------QHTKTTGRR-RA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P62269-1", "uniprot_id": "RS18_HUMAN", "id": "P62269-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62270-1", "uniprot_id": "RS18_MOUSE", "id": "P62270-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM33-1", "uniprot_id": "D3ZM33_RAT", "id": "D3ZM33-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------RKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YVP7-1", "uniprot_id": "F6YVP7_MOUSE", "id": "F6YVP7-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLH-----------------HFWG---------------------LRVRG------QHTKTTGRRGQTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KA79-1", "uniprot_id": "A0A0G2KA79_RAT", "id": "A0A0G2KA79-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRWKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLDRQKDVKD---------------------GKYSQVLAKGLDNKLH-EDLERLKKIRAHRGLR-----------------HFWD---------------------LRVGG------QHSKTTGRRGHTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JGS9-1", "uniprot_id": "RS18_DANRE", "id": "Q8JGS9-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLNKRAGELTEDEVERVVTIMQNPRQYKIPDWFLNRQKDIKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZAU6-1", "uniprot_id": "D3ZAU6_RAT", "id": "D3ZAU6-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVVPKK--FQHSLRVLDTNVDGQRKIALAIT-------------------------------------------------------AIKG----------------------VGWRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDMKD---------------------GKYSQVLANSLDNKLR-EDLERVKKIRAHRGLR-----------------HFWG---------------------LRVRG------RHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41094-1", "uniprot_id": "RS18_DROME", "id": "P41094-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRIMNTNIDGKRKVGIAMT-------------------------------------------------------AIKG----------------------VGRRYSNIVLK---KADVDLTKRAGECTEEEVDKVVTIISNPLQYKVPNWFLNRQKDIID---------------------GKYWQLTSSNLDSKLR-DDLERLKKIRSHRGLR-----------------HYWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O88178-1", "uniprot_id": "B3GT4_RAT", "id": "O88178-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "MPLSLFRRLLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGSGPPPFLLILVCTAPEHLNQRNAIRGSWGAIREARGFRVQTLFLLGEPMGQQFADLASESAAQGDVLQASFQDSYRNLTLKTLTGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEPQEETTAVHKEHKGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPYLPLEDVFVGVSARRVGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWKMQEAWKLVRGLNGRRTEPFCSWLQGFLGTLRCRFIAWLNS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* : .: : * :: .: * : : :*:* :* :::.:. . :.*: . .. : :. : : :. ::*. :.*: * : :. :..: : : : : * * :: . *. *:* . . .* : ", "identical_positions": 17, "similar_positions": 60, "identity": "4.58%" }, { "cls_id": "homologset.agr.FB:FBgn0010412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZX8-1", "uniprot_id": "RS19_MOUSE", "id": "Q9CZX8-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17074-1", "uniprot_id": "RS19_RAT", "id": "P17074-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39019-1", "uniprot_id": "RS19_HUMAN", "id": "P39019-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39018-1", "uniprot_id": "RS19A_DROME", "id": "P39018-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPD-WFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQIVFKQRDAAKQTGPIVISK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07280-1", "uniprot_id": "RS19A_YEAST", "id": "P07280-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P07281-1", "uniprot_id": "RS19B_YEAST", "id": "P07281-1", "name": "Small ribosomal subunit protein eS19B", "aln": "MAGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:*:*: : . .* * **:: ***:** :* ** :. :*:.* * : *** *.** **:* * .***.:.*:*** : .** * :. .: . *:.***** :** .***::: ********* * :. ", "identical_positions": 61, "similar_positions": 40, "identity": "38.85%" }, { "cls_id": "homologset.agr.FB:FBgn0010414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31652-1", "uniprot_id": "SC6A4_RAT", "id": "P31652-1", "name": "Sodium-dependent serotonin transporter", "aln": "METTPLNSQKVLSECKDREDCQENGVLQKGVPTTADRAEPSQISNGYSAVPSTSAGDEASHSIPAATTTLVAEIRQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSLTDRLPWTSCTNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLTLCIVLIFTVIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCVLGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVAVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIVLGYCIGMSSVICIPTYIIYRLISTP-GTLKERIIKSITPETPTEIPCGDIRMNAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60857-1", "uniprot_id": "SC6A4_MOUSE", "id": "Q60857-1", "name": "Sodium-dependent serotonin transporter", "aln": "METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAGPGQISNGYSAVPSTSAGDEAPHSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLISTP-GTLKERIIKSITPETPTEIPCGDIRMNAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31645-1", "uniprot_id": "SC6A4_HUMAN", "id": "P31645-1", "name": "Sodium-dependent serotonin transporter", "aln": "METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITP-GTFKERIIKSITPETPTEIPCGDIRLNAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51905-1", "uniprot_id": "SC6A4_DROME", "id": "P51905-1", "name": "Sodium-dependent serotonin transporter", "aln": "MDRS-GSSDFAGAAATTGRSNPAPWSDDKESPNNEDDSNE---DDGDHTTPAKVT-DPLAPKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCMQVTSEN---FTELATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKTSIDKVGLE-GPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVIGRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGVFWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQPEDNCGSVVPGQQGTSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : .*: : . .. :* *. * .:* :.*: : * . . **..: : *****:* :***:***:******:****************:** :: ****:***********:** **:***::*** :**:*****:* :*:. *****:.**:***::*:*.:****** *.*** ** : ::: :* :****:**: *:**: ::.:**: :* :. *:**:. :*.::***:****:::******** **::* :*****.:**** .*: :**.*:*:** :: **:***:***********.***::**********:***:** :**:***::*****:****** ::: .:.:*. : **.*:**.*.****.*..*.*::****************.***.:***: **:*:: .:*** *** :: .: :* *:* **. :*.:*: *..* *:* *.::**. * ****: :*. **::*** .** ******. ***:*** *: :*. :: :* ** ** :*:.: **.:*** ** *::: :. * ::*: :*: ** . : .:*", "identical_positions": 311, "similar_positions": 184, "identity": "49.29%" }, { "cls_id": "homologset.agr.FB:FBgn0010415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34901-1", "uniprot_id": "SDC4_RAT", "id": "P34901-1", "name": "Syndecan-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MAPVCLFAPLLLLLLGGFPVAPGESIRETEVIDPQD----------------------------------------------------------LLEG---RYFSGALPDDEDAGGLEQDS-DFELSGSGDLDDTEEPRTFPEVISPLVPLDNHIPENAQPGIRVPSEPKELEENEVIPKR------------------------VPSDVGDDDVSNKVSMSSTSQGSNIFERTEVLAALIVGGVVGILFAVFLILLLVY---RMKKKDEGSYDLG----KKPIYKKAPTN---EFYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35988-1", "uniprot_id": "SDC4_MOUSE", "id": "O35988-1", "name": "Syndecan-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MAPACLLAPLLLLLLGGFPLVPGESIRETEVIDPQD----------------------------------------------------------LLEG---RYFSGALPDDEDAGGSD----DFELSGSGDLDDTEEPRPFPEVIEPLVPLDNHIPENAQPGIRVPSEPKELEENEVIPKR------------------------APSDVG-DDMSNKVSMSSTAQGSNIFERTEVLAALIVGGVVGILFAVFLILLLVY---RMKKKDEGSYDLG----KKPIYKKAPTN---EFYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31431-1", "uniprot_id": "SDC4_HUMAN", "id": "P31431-1", "name": "Syndecan-4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MAPARLFA-LLLFFVGG----VAESIRETEVIDPQD----------------------------------------------------------LLEG---RYFSGALPDDEDVVGPGQESDDFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKR------------------------ISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMY---RMKKKDEGSYDLG----KKPIYKKAPTN---EFYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34900-1", "uniprot_id": "SDC2_RAT", "id": "P34900-1", "name": "Syndecan-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MQRAWILLTLGLMACVSAETRAELTSDKDMY----------------------------------------------------------LDSSSIEEAS-GLYPIDDDDYSSASGSGAYEDKGSPDLTTSQLIPRISLTSAA-PEVETMTLKTQSITPTQTESPEETDKKEFEISE--------------------------AEEKQDPAVKSTDVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVY---RMRKKDEGSYDLGERKPSSAAYQKAPTK---EFYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43407-1", "uniprot_id": "SDC2_MOUSE", "id": "P43407-1", "name": "Syndecan-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MQRAWILLTLGLMACVSAETRTELTSDKDMY----------------------------------------------------------LDNSSIEEAS-GVYPIDDDDYSSASGSGADEDIESPVLTTSQLIPRIPLTSAASPKVETMTLKTQSITPAQTESPEETDKEEVDISE--------------------------AEEKLGPAIKSTDVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVY---RMRKKDEGSYDLGERKPSSAAYQKAPTK---EFYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34741-1", "uniprot_id": "SDC2_HUMAN", "id": "P34741-1", "name": "Syndecan-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MRRAWILLTLGLVACVSAESRAELTSDKDMY----------------------------------------------------------LDNSSIEEAS-GVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAA-PKVETTTLNIQNKIPAQTKSPEETDKEKVHLSD--------------------------SERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVY---RMRKKDEGSYDLGERKPSSAAYQKAPTK---EFYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NAW7-1", "uniprot_id": "A0A8M1NAW7_DANRE", "id": "A0A8M1NAW7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MLKVYLMLVLSAAAAVFAESVRETETWVPLK----------------------------------------------------------NKAAIEDLESSGNSQNEDFEFTDLNQTDDEDGFDEDDEDDYDDMSGSGFADVI-DDIEDEFVNNQIPDDKGPFAPRPTVDENILVQNN--------------------EVFLRGAPNQDLDNHSNVLMTHAGDDSLFNNTEVLAAVIAGGAVGLVFAILLIILLVHFVLRIKKKDEGSYDLG----KTPIYKKAPTT---EIYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26260-1", "uniprot_id": "SDC1_RAT", "id": "P26260-1", "name": "Syndecan-1", "aln": "-------------MRRAALWLWLCALALRLQPALPQIVTANVP------------PEDQDGSGDDS--------DNFSGSGTG-------------ALPDMTLSRQTP-------------------------------------------------STWKDVWLLTATPTAPEPTSRDTEATLTSILPAGEKPE-----------------------------------EGEPVAHVEAEPDFTARDKEKEATTRPRETTQLPVTQQASTAARATTAQASVTSHPHGDVQPGLHETLAPTAPGQPDHQPPSVEDGGTSVIKEVVEDETTNQLPAGEGSGEQDFTFETSG------ENTAVAGVEPDLRNQSPVDEGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVAFMLY---RMKKKDEGSYSLEEPKQANGGAYQKPTKQE-EFYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18828-1", "uniprot_id": "SDC1_MOUSE", "id": "P18828-1", "name": "Syndecan-1", "aln": "-------------MRRAALWLWLCALALRLQPALPQIVAVNVP------------PEDQDGSGDDS--------DNFSGSGTG-------------ALPD-TLSRQTP-------------------------------------------------STWKDVWLLTATPTAPEPTSSNTETAFTSVLPAGEKPE-----------------------------------EGEPVLHVEAEPGFTARDKEKEVTTRPRETVQLPITQRAST-VRVTTAQAAVTSHPHGGMQPGLHETSAPTAPGQPDHQPPRVEGGGTSVIKEVVEDGTANQLPAGEGSGEQDFTFETSG------ENTAVAAVEPGLRNQPPVDEGATGASQSLLDRKEVLGGVIAGGLVGLIFAVCLVAFMLY---RMKKKDEGSYSLEEPKQANGGAYQKPTKQE-EFYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18827-1", "uniprot_id": "SDC1_HUMAN", "id": "P18827-1", "name": "Syndecan-1", "aln": "-------------MRRAALWLWLCALALSLQPALPQIVATNLP------------PEDQDGSGDDS--------DNFSGSGAG-------------ALQDITLSQQTP-------------------------------------------------STWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPK-----------------------------------EGEAVVLPEVEPGLTAR--EQEATPRPRETTQLPTTHLAST-TTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSG------ENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLY---RMKKKDEGSYSLEEPKQANGGAYQKPTKQE-EFYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64519-1", "uniprot_id": "SDC3_MOUSE", "id": "Q64519-1", "name": "Syndecan-3", "aln": "MKPGPPRRGTAQGQRVDTATHAPGARGLLLPPLLLLLLAGRAAGAQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDMALAAPTAPAMLPTTVIQPVDTPFEELLSEHPSPEPVTSPPLVTEVTEVVEESSQKATTISTTTSTTAATTTGAPTMATAPATAATTAPSTPEAPPATATVADVRTTGIQGMLPLPLTTAATAKITTPAAPSPPTTVATLDTEAPTPRLVNTATSRPRALPRPVTTQEPDVAERSTLPLGTTAPGPTEMAQTPTPESLLTTIQDEPEVPVSGGPSGDFELQEETTQPDTANEVVAVEGAAAKPSPPLGTL------PKGARPGPGLHDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIY---RMKKKDEGSYTLEEPKQAS-VTYQKPDKQE-EFYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33671-1", "uniprot_id": "SDC3_RAT", "id": "P33671-1", "name": "Syndecan-3", "aln": "MKPGPPRRGTAQGQRVDTATHGPGARGLLLPPLLLLLLAGRAAGAQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDIALAAPTAPAMLPTTVIQPVDTPFEELLSEHPGPEPVTSPPLVTEVTEVVEEPSQRATTISTTTSTTAATTTGAPTMATAPATAATTAPSTPAAPPATATTADIRTTGIQGLLPLPLTTAATAKATTPAVPSPPTTVTTLDTEAPTPRLVNTATSRPRALPRPVTTQEPEVAERSTLPLGTTAPGPTEVAQTPTPESLLTTTQDEPEVPVSGGPSGDFELQEETTQPDTANEVVAVEGAAAKPSPPLGTL------PKGARPGLGLHDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIY---RMKKKDEGSYTLEEPKQAS-VTYQKPDKQE-EFYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49415-1", "uniprot_id": "SDC_DROME", "id": "P49415-1", "name": "Syndecan", "aln": "---------------MKPKQKISVEPLLLVAILIGVLVAATHAQDQKSVKPSAAAPSAAASRPHDEIYIDDDSIEGSGGRGGIHEDLEKDPDYSGSGFGPDDEDAEPDQHSHSSHNTRISQSSNSGINTAHTPTQTSSTIPTTSTSTPMPTTTPTATTPASTTTAAATQISSFANSSSTTTTTLAPTIPAEPQQP------------------------------------LFPPFDKDLDTESSGDGIDADAEDDDEDDGDDKDYDYNKELDKEIDIDGPEPGHLPPVVHHNTVETGHIPTTDEIDVDGGDEDDNGDSDIDGPRIGGNDGDITERGPGAGGSNVHELDPNTNVNSQPSDTKGIDHRPNGNEVVIMSEDDRTSSFFSQPGILAAVIGGAVVGLLCAILVVMFIVY---RMRKKDEGSYALDEPKRSPANNSYAKNANNREFYA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : ..::.. :* .:* *. :* : * :: :::: *::******* * *:**", "identical_positions": 17, "similar_positions": 24, "identity": "3.75%" }, { "cls_id": "homologset.agr.FB:FBgn0010416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B5Y3-1", "uniprot_id": "A0A8I6B5Y3_RAT", "id": "A0A8I6B5Y3-1", "name": "", "aln": "MAGPAPGTIMGEDYFGNASEWGEEADGGQHQEEDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRVAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSRGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGAKINQDHKHKYIHILAYAASVVETWKKNK---RVSIGKDELKSTSKAVETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKAEGEHDPVTEFIAHCKSNFIVVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922L6-1", "uniprot_id": "NELFD_MOUSE", "id": "Q922L6-1", "name": "Negative elongation factor D", "aln": "MAGPAPGTIMGEDYFGNASEWGEEADGGQHQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRVAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSRGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGAKINQDHKHKYIHILAYAASVVETWKKNK---RVSIGKDELKSTSKAIETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKAEGEHDPVTEFIAHCKSNFIVVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXH7-1", "uniprot_id": "NELFD_HUMAN", "id": "Q8IXH7-1", "name": "Negative elongation factor C/D", "aln": "MAGAVPGAIMDEDYYGSAAEWGDEADGGQ-QEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRIAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSKGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGARINQDHKHKYIHILAYAASVVETWKKNK---RVSINKDELKSTSKAVETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKTEGEHDPVTEFIAHCKSNFIMVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24134-1", "uniprot_id": "NELFD_DROME", "id": "Q24134-1", "name": "Negative elongation factor D", "aln": "---------MEVEYD--DSGWQGRAKGQTNPEETLE--DNPQKTIQECLEKFLTPDYIMEPGIFTQLKRYFQSGGSPEEVISMLSENYKAVAQMANLLAEWLILAGVKVTEVQAMVENHLKEMILKSFDPKKADTIFTEEGETPDWLTEMIDHYTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQSEITSISTAAQQIEVFSRVLKTSIVKFLNN-PDDVHGAIQECARMVCHGQHTYVYSQVLIQVLSQEQKGGFNMKRLSQEIIKYALQNNQNVTPITMALNGSAVYPQACQALTSMLTRNTLNPADITVLFRNYSGSDPPPIDLIRNPQFLELLVDALFRSGVKINPEHKPKYMFLLAYASAVIDQPAKKRPMTERMLNKEELKSTIQAIEKAHTICN-VDQGSTELIAELQTLYNCIKYPVVGVGVIRWIENVVMEPSYFKLSTDSCPTHLAVLDEVAAVHPTLQQQILFLLIRLFESKQDELEILVQLEMKKMILDRMVNLLTRGCVVPVLRYIKQCCAIEDTDISLIRYFVTEVLETITHPYSPEFVQLFLPMVENEEITGTMRGEGDNDPVSEFIVHCKAHYTTV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* : * .*.* *: :: :. ****.** * ******.**. ******:*****:**.:*****.**** .******** :**: .:** ******.:::* ***:***:********* ** :** * ***.*:*:*** :*********:*******:*.****:***.**:*******:**:..:*:. :::. : * *:*****:***:::*.::.**:**::** ::*::**: ::* ::.::.: **:**. :* **:***** :**::.:**********: ::. ****::*** * **:*::::**:.*.:** :** **:.:****::*:: *:: . :.*:***** :*:*..*.:* ::*::**:***.***:**::***.:**::*:: .* ** **:*.** *.***:***::: * *: *:* **::***:::.:*::: ***:** :*****:**:** *:**: **::* ***************:.*: **:.:*******::**:.*:**:: **::***:***.***::: * ", "identical_positions": 311, "similar_positions": 184, "identity": "52.36%" }, { "cls_id": "homologset.agr.FB:FBgn0010417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62311-1", "uniprot_id": "TAF6_MOUSE", "id": "Q62311-1", "name": "Transcription initiation factor TFIID subunit 6", "aln": "MAEE-------KKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIP-----FRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEGAPFRLKPRSIHELSVEQQLYYKEITEACVGSCEA------KRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDN----------HWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRGEFGSLGPLLCSHVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSASSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPAGSGSVQKYIVVSLPPTGEGKGGPPSHPSPVPPSSSSPSPLGGSTLCGGKQEAGDSPPPAPGTPKANGSQPTGPGSPQPAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63801-1", "uniprot_id": "TAF6_RAT", "id": "Q63801-1", "name": "Transcription initiation factor TFIID subunit 6", "aln": "MAEE-------KKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIP-----FRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEGAPFRLKPRSIHELSVEQQLYYKEITEACVGSCEA------KRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDN----------HWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRGEFGSLGPLLCSHVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSASSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPAGPGSVQKYIVVSLPPTGEGKGGPPSHPSPVPPSSSSPSPLGGSALCGGKQETGDSPPPAPGTPKANGSQPTGPSSPQPAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49848-1", "uniprot_id": "TAF6_HUMAN", "id": "P49848-1", "name": "Transcription initiation factor TFIID subunit 6", "aln": "MAEE-------KKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIP-----FRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGATTADGKGKEKKAPPLLEGAPLRLKPRSIHELSVEQQLYYKEITEACVGSCEA------KRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDN----------HWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRAEFGSLGPLLCSQVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPSGPGSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEAGDSPPPAPGTPKANGSQPN-SGSPQPAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49847-1", "uniprot_id": "TAF6_DROME", "id": "P49847-1", "name": "Transcription initiation factor TFIID subunit 6", "aln": "MSGKPSKPSSPSSSMLYGSSISAESMKVIAESIGVGSLSDDAAKELAEDVSIKLKRIVQDAAKFMNHAKRQKLSVRDIDMSLKVRNVEPQYGFVAKDFIP-----FRFASGGGRELHFTEDKEIDLGEITSTNSVKIPLDLTLRSHWFVVEGVQPTVPENPPPLSKDSQLLDSVNPVIKMDQGLNKD------------AAGKPTTGKIHKLKNVETIHVKQLATHELSVEQQLYYKEITEACVGSDEP------RRGEALQSLGSDPGLHEMLPRMCTFIAEGVKVNVVQNNLALLIYLMRMVRALLDNPSLFLEKYLHELIPSVMTCIVSKQLCMRPELDN----------HWALRDFASRLMAQICKNFNTLTNNLQTRVTRIFSKALQNDKTHLSSLYGSIAGLSELGGEVIKVFIIPRLKFISERIEPHLLGTSISNTDKTAAGHIRAMLQKCCPPILRQMRSAPDTAEDYKNDFGFLGPSLCQAVVKVRNAPASSIVTLSSNTIN------TAPITSAAQTAT-TIGRVSMPTTQRQGSPGVSSLPQIRAIQANQPAQKFVIVTQNSPQQGQAKVVRR-------GSSPHSVVLSAAS---------NAASASNSNSSSSG-----------------------SLLAAAQRSSDNVCVIAG------------SEAPAVDGITVQSFRAS---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53040-1", "uniprot_id": "TAF6_YEAST", "id": "P53040-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF6", "aln": "MSTQ---------QQSYTIWSPQDTVKDVAESLGLENINDDVLKALAMDVEYRILEIIEQAVKFKRHSKRDVLTTDDVSKALRVLNVEPLYGYYDGSEVNKAVSFSKVNTSGGQSVYYLDEEEVDFDRLINEPLPQVPRLPTFTTHWLAVEGVQPAIIQNPNLNDIRVSQPPFIRGAIVTALNDNSLQTPVTSTTASASVTDTGASQHLSNVKPGQNTEVKPLVKHVLSKELQIYFNKVISTLTAKSQADEAAQHMKQAALTSLRTDSGLHQLVPYFIQFIAEQITQNLSD--LQLLTTILEMIYSLLSNTSIFLDPYIHSLMPSILTLLLAKKLGGSPKDDSPQEIHEFLERTNALRDFAASLLDYVLKKFPQAYKSLKPRVTRTLLKTFLDINRVFGTYYGCLKGVSVLEGESIRFFLGNLNNWAR----------LVFNESGITLDNIEEHLNDDSNPTRTKFT---------KEETQILVDTVISALLVLKKD---------------------------------------LPDLYEGKGEKVTDEDKEKLLERCGVTIGFHILKRDDAKELISAIFFGE-------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : . :::* :***:*: .:.::. : *: :*. :: .* ::* ** . .**: *:. *:. :*:: **** **: . : :. :.**:.::: :::*:*:. : . ::* : :**: :** **:: :** . . . :. . .. : : .:* * ** * *:*:::: .: ... :. : ** *: :*.**::::* : **:* : *: : * ** ::.*: :*:.*.:::*: *:*.*:*:::* :::::* *. *. ******: *: : *:* :.::.*:*: : *: : : : **.: *:: * : *: :: : : * . .::. * . . * :: : : * : . :: : :* : . : . * ::. ... :. ", "identical_positions": 92, "similar_positions": 180, "identity": "13.03%" }, { "cls_id": "homologset.agr.FB:FBgn0010421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01750-1", "uniprot_id": "T2FB_RAT", "id": "Q01750-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MAERG-------ELDLTGAKQNTGVWLVKVPKYLSQQWAKAP--GRGEVGKLRIAK-------------NQG-RTEVSFTLN----------------------------------------EDLANIHDIGGKPASVSAPREHPFVLQSVG--GQTLTVFTESSSDKLSLEGIVVQRAECRP-AASENYMKLKR-----LQIEESSKPVRLSQQADKVVTTNYKPVANHQYNIEYERKKKEDG--KRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEEKSD-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0A0-1", "uniprot_id": "T2FB_MOUSE", "id": "Q8R0A0-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MAERG-------ELDLTGAKQNTGVWLVKVPKYLSQQWAKAS--GRGEVGKLRIAK-------------NQG-RTEVSFTLN----------------------------------------EDLANIHDIGGKPASVSAPREHPFVLQSVG--GQTLTVFTESSSDKLSLEGIVVQRAECRP-AASENYMKLKR-----LQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDG--KRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEEKSD-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13984-1", "uniprot_id": "T2FB_HUMAN", "id": "P13984-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MAERG-------ELDLTGAKQNTGVWLVKVPKYLSQQWAKAS--GRGEVGKLRIAK-------------TQG-RTEVSFTLN----------------------------------------EDLANIHDIGGKPASVSAPREHPFVLQSVG--GQTLTVFTESSSDKLSLEGIVVQRAECRP-AASENYMRLKR-----LQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDG--KRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41900-1", "uniprot_id": "T2FB_DROME", "id": "P41900-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MSKEDKEKTQIIDKDLDLSNAGRGVWLVKVPKYIAQKWEKAP--TNMDVGKLRINK-------------TPGQKAQVSLSLTPAVLA-------------------------------LDPEEKIPTEHILDVSQVTKQTLGVFSHMAPSDGK-ENSTTSAAQPDNEKLYMEGRIVQKLECRP-IADNCYMKLKL-----ESIRKASEPQRRVQPIDKIVQN-FKPVKDHAHNIEYRERKKAEG--KKARDDKNAVMDMLFHAFEKHQYYNIKDLVKITNQPISYLKEILKDVCDYNMKNPHKNMWELKKEYRHYKTEEKKEEEHKSGSSDSE------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41896-1", "uniprot_id": "T2FB_YEAST", "id": "P41896-1", "name": "Transcription initiation factor IIF subunit beta", "aln": "MSSGSAGAPALSNNSTNSVAKEKSGNISGDEYLSQEEEVFDGNDIENNETKVYEESLDLDLERSNRQVWLVRLPMFLAEKWRDRNNLHGQELGKIRINKDGSKITLLLNENDNDSIPHEYDLELTKKVVENEYVFTEQNLKKYQQRKKELEADPEKQRQAYLKKQEREEELKKKQQQQKRRNNRKKFNHRVMTDRDGRDRYIPYVKTIPKKTAIVGTVCHECQVMPSMNDPNYHKIVEQRRNIVKLNNKERITTLDETVGVTMSHTGMSMRSDNSNFLKVGREKAKSNIKSIRMPKKEILDYLFKLFDEYDYWSLKGLKERTRQPEAHLKECLDKVATLVKKGPYAFKYTLRPEYKKLKEEERKATLGELADEQTGSAGDNAQGDAEADLEDEIEMEDVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . ** . . ****::* :::::* . ::**:** * . . : .: *. * : . . . . : : .:. .* : * : :. : * . * :: .:.: .. : . : .: .. *: ::* .. * * *: ::* ** *::::*:.:*.* . *.** :*** *..: *. : : *: **:: : **:. ", "identical_positions": 44, "similar_positions": 86, "identity": "11.0%" }, { "cls_id": "homologset.agr.FB:FBgn0010422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLL0-1", "uniprot_id": "TCEA1_RAT", "id": "Q4KLL0-1", "name": "Transcription elongation factor A protein 1", "aln": "---MEDEVVRIAKKMDKMVQK-KNAAGALDLLKELK-NIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSE------------------------------------------------------------------EKKKEPAI------------------------------------------------------------------------------------------------------------------------SSQNSPEAR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESSSSSHVSSRKDETNARDTYVSSFP--------RAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10711-1", "uniprot_id": "TCEA1_MOUSE", "id": "P10711-1", "name": "Transcription elongation factor A protein 1", "aln": "---MEDEVVRIAKKMDKMVQK-KNAAGALDLLKELK-NIPMTLELLQSTRIGMSVNALRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDPE------------------------------------------------------------------EKKKEPAI------------------------------------------------------------------------------------------------------------------------SSQNSPEAR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESSSSSNVSSRKDETNARDTYVSSFP--------RAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23193-1", "uniprot_id": "TCEA1_HUMAN", "id": "P23193-1", "name": "Transcription elongation factor A protein 1", "aln": "---MEDEVVRFAKKMDKMVQK-KNAAGALDLLKELK-NIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLD------------------------------------------------------------------EKKKEPAI------------------------------------------------------------------------------------------------------------------------TSQNSPEAR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EESTSSGNVSNRKDETNARDTYVSSFP--------RAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QVN7-1", "uniprot_id": "TCEA2_MOUSE", "id": "Q9QVN7-1", "name": "Transcription elongation factor A protein 2", "aln": "-MGKEEEIARIARRLDKMVTR-KNAEGAMDLLRELK-NMPITLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLD-VSDGKSRN------------------------------------------------------------------QGRGTPLP------------------------------------------------------------------------------------------------------------------------TSSSKDASR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTDLSCKKPDPPRTPSTPR---ITTFP--------QVPITCDAVRNKCREMLTLALQTDHDHVAVGVNCEHLSSQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCNKCRKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63799-1", "uniprot_id": "TCEA2_RAT", "id": "Q63799-1", "name": "Transcription elongation factor A protein 2", "aln": "-MGKEEEIARIARRLDKMVTR-KNAEGAMDLLRELK-NMPITLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLD-VSDGKSRD------------------------------------------------------------------QGRGTPLP------------------------------------------------------------------------------------------------------------------------TSSSKDASG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTDLSCKKPDPPRTSSTPR---ITTFP--------QVPITCDAVRNKCREMLTLALQTDHDHVAVGVSCEHLSSQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCNKCRKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15560-1", "uniprot_id": "TCEA2_HUMAN", "id": "Q15560-1", "name": "Transcription elongation factor A protein 2", "aln": "MMGKEEEIARIARRLDKMVTK-KSAEGAMDLLRELK-AMPITLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLD-ASDAKARE------------------------------------------------------------------RGRGMPLP------------------------------------------------------------------------------------------------------------------------TSS-RDASE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APDPSRKRPELPRAPSTPR---ITTFP--------PVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23881-1", "uniprot_id": "TCEA3_MOUSE", "id": "P23881-1", "name": "Transcription elongation factor A protein 3", "aln": "-MGLEEELLRIAKKLEKMVSR-KKTEGALDLLKKLN-SCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLDSPRTTKGER------------------------------------------------------------EEREKAKK-EKGLG------------------------------------------------------------------------------------------------------------------------CSDWKPEAG-----------------------LSPP---------------------------------------------------------------------------------------------------------RKKGGGEPKTR---------------------------------------------------------------------------------------------------------RDSVDSRSS------TTSSPKR-------------PSLERSNSSKSKVETPTTPS---SPSTPTFAP-AVCLLAPCYLTGDSVRDKCVEMLSAALKAEDNFKDYGVNCDKLASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISPELIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLLRCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EY03-1", "uniprot_id": "F7EY03_RAT", "id": "F7EY03-1", "name": "Transcription elongation factor", "aln": "-MGLEEELLRIAKKLEKMVAR-KKTEGALDLLKKLN-SCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLDSPRTTKGER------------------------------------------------------------EAREKAKKKEKGLG------------------------------------------------------------------------------------------------------------------------SSGWKPEAG-----------------------LSPP---------------------------------------------------------------------------------------------------------RKKEGGEPKTR---------------------------------------------------------------------------------------------------------RDSVDSRSS------TTSSPKR-------------PSLERSNSSRSKVETPKTPS---SPSTPTFAP-AVCLLASCYLTGDSVRDKCVEMLSAALKAEDDFKDYGVNCDKLASEIETHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGTISPELIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLLRCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75764-1", "uniprot_id": "TCEA3_HUMAN", "id": "O75764-1", "name": "Transcription elongation factor A protein 3", "aln": "-MGQEEELLRIAKKLEKMVAR-KNTEGALDLLKKLH-SCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLDSPGPPKGEKG-----------------------------------------------------------EEREKAKKKEKGLE------------------------------------------------------------------------------------------------------------------------CSDWKPEAG-----------------------LSPP---------------------------------------------------------------------------------------------------------RKKRE-DPKTR---------------------------------------------------------------------------------------------------------RDSVDSKSS------ASSSPKR-------------PSVERSNSSKSKAESPKTPS---SPLTPTFAS-SMCLLAPCYLTGDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4P3-1", "uniprot_id": "A0A8M2B4P3_DANRE", "id": "A0A8M2B4P3-1", "name": "", "aln": "-MTREEDLLRIAKKLDKMVSR-NNMDGALDLLRELK-DFNMTLKLLQDTRIGMSVNGIRKHCTDEDVVNLAKILIKNWKRLLESAQNPKSERPNEVKNGSHPSKPSGSPSRTSPEKDSSLRRSTAEIKPDLDSNKKLDEKQRREKIDAEFRKEKRESNQKKEKQSINNKKDQERKDALNSDHLPSPLTLSSVPLKCPPTGEVKWERKDAPVDFFPPPSINSHPPLRRSSVDVKRKDTQSSVHSPALQSHPPKRPFIDGKKERRDTNDLLFPLHHPLPPPPIPIPKRSSEVKKERKDPPEMLPPPTPVLSTPPPPPKRVLSPPPPPPKRVLSPPPPKHVLSAPSPPLPKRTSLEENKESKERVKKAADPNAPLAPLPFHLHPPQKREMKKERKETVDPSAPFPPVPLHLQPPTPTKRPSLDTKKDKEKERKDTSDPKRRTSEHNERERKDTSDSKRRTSEHNERERKDTADQKRRTSEHNEKERKDTSDPKRQTSVHNDKDRKDTRDNKLLKRPSMKIKIERKDSTDSKKPLPRKPSLDGRRDSKDSTDSKSSNHLLKRQSSEPKLERRDSTNSRSGSSPQAKKSCESKSKPETPKTPTTPTSPLSPSFSS-SAGPLSPRLQTGDSIRDKCIEMLTAALRTDDDYKDYGTNCEAMGAEIEDYIYQETKATDMKYKNRVRSRISNLKDPKNPNLRKNVLAGAIELSRIASMTAEEMASDELKQLRNVLTQEAIREHQMAKTGGTTTDLLQCGKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20232-1", "uniprot_id": "TFS2_DROME", "id": "P20232-1", "name": "Transcription elongation factor S-II", "aln": "-MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQ-TLNINLDILTKTRIGMTVNELRKSSKDDEVIALAKTLIKNWKRFLASPAPTTPNNS-----------------------------------------------------------SAKEGSSNNSSASKS-----------------------------------------------------------------------------------------------------------------------TSAAKSSSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISGKDKSSSSSSSKDKEKKGSTSSSQTSFP---------SGGMTDAVRIKCREMLATALKIGEVPEGCGEP-EEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWKFC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07273-1", "uniprot_id": "TFS2_YEAST", "id": "P07273-1", "name": "Transcription elongation factor S-II", "aln": "--MDSKEVLVHVKNLEKNKSN---DAAVLEILHVLDKEFVPTEKLLRETKVGVEVNKFKKS-TNVEISKLVKKMISSWKDAINKNKRSRQAQQ-----------------------------------------------------------------HHQDHAPG------------------------------------------------------------------------------------------------------------------------NAEDKTTVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESVNGVQQPASSQSDAMKQDKYVSTKPRNSKNDGVDTAIYHHKLRDQVLKALYDVLAKESEHPPQSILHTAKAIESEMNKVNNCDTNEAAYKARYRIIYSNVISKNNPDLKHKIANGDITPEFLATCDAKDLAPAPLKQKIEEIAKQNLYNAQGATIERSVTDRFTCGKCKEKKVSYYQLQTRSADEPLTTFCTCEACGNRWKFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: :.:.* .:::*: *. . .:* *::*: ** .:* .: :: *.* :*..** : : . .: . . :* : : * .* . . : * : .: *: * * :*: . .**.*: :. * : :* .:::*. ::: : :.:: : : * * : ** : * **:::: :* *:****:***:**: *: *******.", "identical_positions": 54, "similar_positions": 86, "identity": "6.86%" }, { "cls_id": "homologset.agr.FB:FBgn0010425", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKQ9-1", "uniprot_id": "KLK9_HUMAN", "id": "Q9UKQ9-1", "name": "Kallikrein-9", "aln": "------------MKLGLLCALLSL---------------LAGHGWA-------------------DTRAIGAEECRPNSQPWQAGLFHLT--RLFCGATLISDRWLLTAAHCRKPY--------LWVRLGEHHLW-KWEGPEQLFRVTDFFPHPGFNKDLSA-------NDHNDDIMLIRLPRQARLSPAVQPLNLSQTCV--SPGMQCLISGWGAVSSPKA----LFPVTLQCANISILENKLCHW--------AYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNG-----TLAGVVSGG-AEPCSRPRRPAVYTSVCHYLDWIQEIMEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKR0-1", "uniprot_id": "KLK12_HUMAN", "id": "Q9UKR0-1", "name": "Kallikrein-12", "aln": "------------MGLS-IFLLLCV---------------LGLSQAA-------------------TPKIFNGTECGRNSQPWQVGLFEGT--SLRCGGVLIDHRWVLTAAHCSGSR--------YWVRLGEHSLS-QLDWTEQIRHSGFSVTHPGYLG--AS-------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCA--TAGTECHVSGWGITNHPRN----PFPDLLQCLNLSIVSHATCHG--------VYPGRITSNMVCAGGVPG-QDACQGDSGGPLVCGG-----VLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "-----------MLLLLTILQALAV---------------AIVQSQG-------------------DDKILGGYTCVQNSQPWQVALQAGPGRRFLCGGVLLSDQWVITAAHCARPL--------LHVALGKHNLR-RWEATQQVLRVVRQVPHPQYRP-----------QAHDNDLMLLKLQRKVRLGRAVRTIPVARSCA--SPGTPCRVSGWGTTASPIV----RYPTALQCVNVNIMPEQVCHR--------AYPGTITSGMVCAGVPEGGKDSCQGDSGGPLVCQG-----QLQGLVSWG-MERCAMPGYPGVYTNLCNYHSWIQRTMQSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5K2-1", "uniprot_id": "KLK4_HUMAN", "id": "Q9Y5K2-1", "name": "Kallikrein-4", "aln": "-MATAGNPWGWFLG----YLILGV---------------AGSLVSG------------------SCSQIINGEDCSPHSQPWQAALVM-EN-ELFCSGVLVHPQWVLSAAHCFQNS--------YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIASQCP--TAGNSCLVSGWGLLANGR------MPTVLQCVNVSVVSEEVCSK--------LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "MMVTARTPWGWFLG----CLILEV---------------TGASASS------------------VSSRIIQGQDCSPHSQPWQAALFS-ED-GFFCSGVLVHPQWVLSAAHCLQES--------YIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFND-----------PSFANDLMLIKLNESVIESNTIRSIPVATQCP--TPGDTCLVSGWGQLKNGK------LPSLLQCVNLSVASEETCRL--------LYDPVYHLSMFCAGGGQDQKDSCNGDSGGPIVCNR-----SLQGLVSMG-QGKCGQPGIPSVYTNLCKFTNWIQTIIQTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRA7-1", "uniprot_id": "D3ZRA7_RAT", "id": "D3ZRA7-1", "name": "", "aln": "-MARAGHPWKWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPN-KLYCGAVLINPQWLLTAAHCRKPV--------FRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSH-----------PGHSNDLMLIKMNRKIRASHSVKPVEITSDCP--KEGTRCMVSGWGTTSSSHN----NFPKVLQCLDITVLSEERCKN--------SYPGQIDKTMFCAG-DEAGRDSCQGDSGGPVICNG-----KLQGLVSWG-DFPCAQPNRPGVYTNLCEFVPWIKDTIHSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "---------MWFLILFLALSLGQI----------------DAAPPG-------------------QSRVVGGYNCETNSQPWQVAVIG----TTFCGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLV-KDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEP--KVGSICLASGWGMTNPSE----MKLSHDLQCVNIHLLSNEKCIE--------TYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDG-----VLQGLTSGG-ATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMU8-1", "uniprot_id": "A0A8I6AMU8_RAT", "id": "A0A8I6AMU8-1", "name": "tissue kallikrein", "aln": "---------NFFLYFFLDQVIIEQ----------------NAAPPG-------------------QSRVVGGYKCEKNSQPWQVAVIS----RSLCGGVLIDPSWVITAAHCYSNY--------YHVLLGRNNLS-EDEPFAQYRFVSQSFPHPDYNPFFMRNHTRQPGDDYSNDLMLLHLSKPADITDGVKVIDLPTEEP--KVGSTCLASGWGSTKPLDYRMWLGSAHDPLCVNIHLLSNEKCIE--------AYNEKVTDLMLCAGDLEGGKDTCKGDSGGPLICDG-----VLQGITSWG-SDPCAEPNMPAIYTKLIKFTSWIKEVMKENS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35005-1", "uniprot_id": "TRYE_DROME", "id": "P35005-1", "name": "Trypsin epsilon", "aln": "-----------MLKFAVLLSVLACA-------------LAGTIPDG--------------LLPQLDGRIVGGYETSIDAHPYQVSLQRYG--SHFCGGSIYSHDIVITAAHCLQSI--------EAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNS-----------RTMVNDIAIIRIESDLSFRSSIREIRIADSNP--REGATAVVSGWGTTESGGS----TIPDHLLAVDLEIIDVSRCRSDE-----FGYGKKIKDTMLCAY--APHKDACQGDSGGPLVSGD-----RLVGVVSWG--YGCGDVRYPGVYADVAHFHEWIERTAEEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "--------MARHLLLPLVMLVISP--------------IPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDG-AHTRAVAAIVVPANYSQ-----------VELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADP---LPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEG-GRWFQAGITSFG--FGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLRPRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "--------MSPHLFLPVVVLVVSP--------------TPGAFQDSAVSPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLHHGGG--HICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEG-AHMRSVATILVPDNYSR-----------VELGADLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDP---LPVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCEDG-GRWFLAGITSFG--FGCGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDS------LHDFETWRVLLPSRPEEKRVVRLVAHENASRNFASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLRPRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALPLLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "----MKWCWGPVLLIAGATVLMEG-------------LQAAQRACG---------------QRGPGPPKPQEGNTVPGEWPWQASVRRQG--AHICSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHY------------SQGSDLALLQLAHPTTHT----PLCLPQPAHRFPFGASCWATGWDQDTSDAP-------GTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFA--SSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQAG----APSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLG------TRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLG----PRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSS---LDWQVYFAEEPEPEAEPGSCLANISQPTSC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "----MRQSWRPELLIVGAVVVIEG-------------LQAAQRACG---------------QRGPGPPEPQEGNTLPGEWPWQASVRRQG--VHICSGSLVADTWVLTAAHCFEKMATAELS-SWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHY------------SQGSDLALLQLTHPTVQT----TLCLPQPTYHFPFGASCWATGWDQNTSDVS-------RTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFT--SKCAQEDTPVLLTDMAVHSSWLQAHVHEAAFLVQAPGVVKMSDENSCVACGSLRSAGPQAG----ALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGRQTLEEWSVGLG------AGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLG----PMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISN---LDWQVYFAEEPEPEAETGSCLVNSSQPASC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *:* .: *.. : :::**** * *: :::: : :. * . :**. : : * .*. :..* ******::. *: * *. * : : . *:. ", "identical_positions": 26, "similar_positions": 39, "identity": "2.9%" }, { "cls_id": "homologset.agr.FB:FBgn0010433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH80-1", "uniprot_id": "A0ABK0LH80_RAT", "id": "A0ABK0LH80-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MKSACKPHGPPAGARGAPPCAG--------------------------AAERAVSCAGPGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIVALTRILAEAER------DWVGLRCE--------QRGRNHPYLPFPGARLQVDPEP--------------------YGQKFFGFQPESFPMAS-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E5-1", "uniprot_id": "ATOH7_MOUSE", "id": "Q9Z2E5-1", "name": "Transcription factor Atoh7", "aln": "-----------------------------------------------------------------------------------------MKSACKPHGPPAGARGAPPCAG--------------------------AAERAVSCAGPGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAER------DWVGLRCE--------QRGRDHPYLPFPGARLQVDPEP--------------------YGQRLFGFQPEPFPMAS-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N100-1", "uniprot_id": "ATOH7_HUMAN", "id": "Q8N100-1", "name": "Transcription factor ATOH7", "aln": "-----------------------------------------------------------------------------------------MKS-CKPSGPPAGARVAPPCAG--------------------------GTECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGS-ERDWVGLHCE--------HFGRDH-YLPFPGAKLPGESEL--------------------YSQRLFGFQPEPFQMAT-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW52-1", "uniprot_id": "ATOH7_DANRE", "id": "Q8AW52-1", "name": "Transcription factor atoh7", "aln": "---------------------------------------------------------------------------------------------MKPR--------RPSCAD--------------------------SGSDSDSRD-PEKFESAMRRRMAANARERKRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALNRILSDAGRHVDPQKDWLNLQFD--------GLQTEGYFMHYDS---PVESD---------------------CMLSSFSYHYESL---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZQL9-1", "uniprot_id": "D3ZQL9_RAT", "id": "D3ZQL9-1", "name": "", "aln": "MSRLLHAEEWAEVKELGDHHRHPQPHHIPQLTPQPPATLQARDHPVYPAELSLLDSTDPRAWLTPTLQGLCTARAAQYLLHSPELGASEAAAPGDEADGQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSVGEQPPPPAASCKNDHHHLRAAASYEGGAGASAVAGAQPAPGGGPRPTPPGACRTRFSTPASSGGYSVQLDALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVPEDSSKTSPRSHRSDGEFSPHSHYSDSDEAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48985-1", "uniprot_id": "ATOH1_MOUSE", "id": "P48985-1", "name": "Transcription factor Atoh1", "aln": "MSRLLHAEEWAEVKELGDHHRHPQPHHVPPLTPQPPATLQARDLPVYPAELSLLDSTDPRAWLTPTLQGLCTARAAQYLLHSPELGASEAAAPRDEADSQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPNVGEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAPGGGPRPTPPGPCRTRFSGPASSGGYSVQLDALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVQEDNSKTSPRSHRSDGEFSPHSHYSDSDEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q9E7-1", "uniprot_id": "A0A8M9Q9E7_DANRE", "id": "A0A8M9Q9E7-1", "name": "", "aln": "-------------------------------MPHPDTPFG------------------------------------QFIWRETDRSHSEQCPKAPMGWREEQLQDRASCD-----------PCALVQLR----LTGLSYSSEEQSS---IARARRRRRLAANARERRRMLGLNVAFDRLRSVIPNVESDRKLSKSETLQMAQIYISTLSELLEDKDCDPETPYPTLTMQ----------DQDITKGLPMTEETKTELKNNP------TCRIRS--------YNGNFGCLTCSDHKTAELLVDSHCLERNNGVK--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48987-1", "uniprot_id": "ATO_DROME", "id": "P48987-1", "name": "Protein atonal", "aln": "-----------MSSSEIYRYYYKTSEDLQGFKTAAAEPYFNPMAAYNPGVTHYQFNGNTLASSSNYLSANGFISFEQASSDGWISSSPASHRSESPEYVDLNTMYNGGCNN--------------------------MAQNQQYGMIMEQSVVSTAPAIPVASPPAVEVMGS-SNVGTCKTIPASAGPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLLR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :.. : .: * .. : : .. . * * :. * : : . ", "identical_positions": 5, "similar_positions": 19, "identity": "1.42%" }, { "cls_id": "homologset.agr.FB:FBgn0010434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K162-1", "uniprot_id": "A0A0G2K162_RAT", "id": "A0A0G2K162-1", "name": "", "aln": "----------------------------------MTTEVASASEVKKGSDPS----GADAHKEKAKEVVENEQTAASELDEGKASQPGPTAESQSSPHRRKRGKD---PSENRGISRFIPPWLKKQKSYSLVVAKDGGDKKEPTQADGEDQILDKEDTLPEEESRAKGDAEEMAQRKHLEVKVEVREEKSALK-------SSAEIQPAEQVRKDKEEEVIQDIQEEKLEGGAAKRETKEVQTSELKAEVASQKAAKKTKTVLAKVTLLDGTEFSCDLEKRAKGQALFDRVCEHLNLLEKDYFGLIFQEHPEQKNWLDPAKEIKRQLRSLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDISSGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDS-IDLGDFQFAPTHNKELEEKVAELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPGELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKT-KFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKR--VSRSLDG-----------------APIGVVDQSLMKDFPGPPGEGSVPGPG-------------VVSYTTVQDG--RRDGK-SPTKVTPL-LAEGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNTLRVDGDNIYVR-----------------------------------------------------------------------------------------------------------------------------------------------HSNLMLEDLDKAQEAILKHQASVSELKRNFMESTPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRPS-----------------------------------------------------------------------------------------------------EWEKRRVTPLSCQILARNSQTLFKDILSAKLMSQMAAARTPEEATQVHKTPRALVSEGPCTGTRDAVKSSHETLNVVEEKKRAEVGK-----------------------------------------------GESVITEEMNGKELSPGSGPGETRKVEPMAHKDSTSLSSESSSSSSESEE-DVGEYQPHHRVTEGTIREEQE-YEEELEEEPGQGAKVVEREAAMPEAIPDRQAGASVLPVETEAQENVVAQKLPGEKGAHRGTAEQDMSEEAEEDQHRVNGEVPHLDIDGLPEIVCPSEPPVVKTEMVTIS-------------DAS---QRTEISTKEVPIVQTETKTITYESPQIDGGAG-GDSGVLLT------------AQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAA-LDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGED------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70318-1", "uniprot_id": "E41L2_MOUSE", "id": "O70318-1", "name": "Band 4.1-like protein 2", "aln": "----------------------------------MTTEVGSASEVKKGSDQA----GADASKEKAKEVE-NEQTPVSEPEEEKGSQPGPPVERQSTPRLRKRGKD---PSENRGISRFIPPWLKKQRSYNLVVAKDGGDKKEPTQADVEDQILGKEESLPEEESRAKGDAEEMAQRKHLEVQVEVREAKPALK-------SSVETQPAEEVRKDKEE-TIQDTQEEKLEGGAAKRETKEVQTSELKAEVASQKATKKTKTVLAKVTLLDGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDHPEQKNWLDPAKEIKRQLKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDS-IDLGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKT-KFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKR--VSRSLDG-----------------APIGVVDQS-------PPGEGSVPGPG-------------VISYTTIQDG--RRDSK-SPTKATPL-PAEGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNTLRVDGDNIYVR-----------------------------------------------------------------------------------------------------------------------------------------------HSNLMLEDLDKAQEAILKHQASISELKRNFMASTPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRPS-----------------------------------------------------------------------------------------------------EWEKRRVTPLPFQPQA----------------------------------------------------SSHETLNVVEEKKRAEVGK-----------------------------------------------DESVITEEMNGKEMSPGHGPGETRKVEPVAHKDSTSLSSESSSSSSESEE-DVGEYQPHHRVTEGTIREEQEECDEELEEEPGQGAKVVEREAAVPDAVPDRQAGASVLPVETEAQEHVVAQKLPGEKGAHGGTAEQDPREEAEEDPHRVNGEVPHLDLDGLPEIICCSEPPVVKTEMVTIS-------------DAS---QRTEISTKEVPIVQTETKTITYESPQIDGGAG-GDSGVLLT------------AQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAA-LDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGEE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43491-1", "uniprot_id": "E41L2_HUMAN", "id": "O43491-1", "name": "Band 4.1-like protein 2", "aln": "----------------------------------MTTEVGSVSEVKKDSSQL----GTDATKEKPKEVAENQQNQSSDPEEEKGSQPPPAAESQSSLRRQKREKE---TSESRGISRFIPPWLKKQKSYTLVVAKDGGDKKEPTQAVVEEQVLDKEEPLPEEQRQAKGDAEEMAQKKQ-EIKVEVKEEKPSVSKEEKPSVSKVEMQPTELVSKEREE-KVKETQEDKLEGGAAKRETKEVQTNELKAEKASQKVTKKTKTVQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLDPAKEIKRQLRNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAELGDYDPEEHGS-IDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKA-KFLTLGSKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKR--VSRSLDG-----------------APIGVMDQSLMKDFPGAAGEISAYGPG-------------LVSIAVVQDGDGRREVR-SPTKAPHLQLIEGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNSLRVEGDNIYVR-----------------------------------------------------------------------------------------------------------------------------------------------HSNLMLEELDKAQEDILKHQASISELKRNFMESTPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRPN-----------------------------------------------------------------------------------------------------EWEKRRITPLSLQTQG----------------------------------------------------SSHETLNIVEEKKRAEVGK-----------------------------------------------DERVITEEMNGKEISPGSGPGEIRKVEPVTQKDSTSLSSESSSSSSESEEEDVGEYRPHHRVTEGTIREEQE-YEEEVEEEPRPAAKVVEREEAVPEASPVTQAGASVITVETVIQENVGAQKIPGEKSVHEGALKQDMGEEAEEEPQKVNGEVSHVDIDVLPQIICCSEPPVVKTEMVTIS-------------DAS---QRTEISTKEVPIVQTETKTITYESPQIDGGAG-GDSGTLLT------------AQTITSESVSTTTTTHITKTVKGGISETRIEKRIVITGDGD-IDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGED------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LHG8-1", "uniprot_id": "A0ABK0LHG8_RAT", "id": "A0ABK0LHG8-1", "name": "Protein 4.1", "aln": "MSHFCSLLPCAAVTMAALSLPAWLCDNNVYLWNIMTTEKSLAAEAENSQHQ--KEEGEGATNSGQQESQLEEASQAAAAEGSNQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQ---VSEEEGREVESEREKGEGEQKETELGTSLDEDVILKAPIAAP---EPELKTDPSLDLHSLS--------SIETQPAQEEHREDPDSETKEG-EGIEECSGTEVKED-PESRAEREPETSQKPIRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAVWDSTTSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTVQSELGDYDPELHGV-DYVSDFKLAPNQTRELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTLPKS-KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR--ASRSLDG-----------------AAAAESTDRSPRPTSAPAIAQSQVMEG-------PGAPAKKAPKEAVKVEE-KRGEE-PAEP-EPEPTEAWK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKRERLDGENIYIR-----------------------------------------------------------------------------------------------------------------------------------------------HSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRPS-----------------------------------------------------------------------------------------------------EWDKRLST-----------------------------------------------------------HSPFRTLNIN-----GQVPT-----------------------------------------------GDGSVNGIRTEEVASVTQGPSAYPASERECPKQSVVPSESLMTTPPESPQ----------SFGSGSLSKNSKEAKETEEKEQGAGGHLGAEERPTGPRGECLGVEEQASALSFPVTPASRQLHLGGEKADSS----EEPGAPAETPETQSGSFLDSPVGNQFPILTRSFQPPLVKTQTVTIS-------------DTANA-VKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLT------------AQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDAD-IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48193-1", "uniprot_id": "EPB41_MOUSE", "id": "P48193-1", "name": "Protein 4.1", "aln": "----------------------------------MTTEKSLAAEAENSQHQQQKEEGEGATNSGQQETQLEEASQAAAAEGSDQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQ---VSEEEGREVESEKEKGEGGQKEIELGNSLDEDIILKAPIAAP---EPELKTDPSLDLHSLS--------SIETQPAQEEHREDPDSETKEG-EGIEECSGTEVKED-PESRAEREPEASQKPVRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLALWDSATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGM-DYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKS-KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR--ASRSLDG-----------------AAAAESTDRSPRPTSAPAIAQSQVTEG-------PGAPIKKTPKEAVKVEE-KRGEE-PAEPAEPEPTEAWKVEKTHTEVTVP-------------------------------------------------------------------------------------------------------------------------------------------------------------TSNGDQTQKLAGKGEDLIRMRKKKRERLDGENIYIR-----------------------------------------------------------------------------------------------------------------------------------------------HSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRPS-----------------------------------------------------------------------------------------------------EWDKRLST-----------------------------------------------------------HSPFRTLNIN-----GQVPT-----------------------------------------------GDG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLVKTQTVTIS-------------DTANA-VKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLT------------AQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDAD-IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11171-1", "uniprot_id": "EPB41_HUMAN", "id": "P11171-1", "name": "Protein 4.1", "aln": "----------------------------------MTTEKSLVTEAENSQHQQ-KEEGEEAINSGQQEPQQEESCQTAAE-GDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQ---VSEEEGKEVESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAP---EPELKTDPSLDLHSLS--------SAETQPAQEELREDPDFEIKEG-EGLEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGV-DYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKS-KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR--ASRSLDG-----------------AAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEV-KKEDE-PPEQAEPEPTEAWKVEKTHIEVTVP-------------------------------------------------------------------------------------------------------------------------------------------------------------TSNGDQTQKLAEKTEDLIRMRKKKRERLDGENIYIR-----------------------------------------------------------------------------------------------------------------------------------------------HSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRPS-----------------------------------------------------------------------------------------------------EWDKRLST-----------------------------------------------------------HSPFRTLNIN-----GQIPT-----------------------------------------------GEG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLVKTQTVTIS-------------DNANA-VKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLT------------AQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDAD-IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y2J2-1", "uniprot_id": "E41L3_HUMAN", "id": "Q9Y2J2-1", "name": "Band 4.1-like protein 3", "aln": "----------------------------------MTTESGSDSESKPDQEAE--------------------PQEAAGAQGRAGA-PVPEPPK--------------------------------------------------------------EEQQQALEQFAAAAAHSTP------VRREVTDKEQEFA----------ARAAKQLEYQQLEDDKLSQK------------------SSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGS-DYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPK--KFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQTNLITTVTPEK-------------KAEEERDEEEDKRRKGE-EVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESD------------------------------------------------------------------------------------------------------------------------------------------QEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAVTN----------------------------------------------------------------------------------------------------EWEKRLSTSPVR------------------------------------------------------LAARQEDAPMIEPLVPEETKQ-----------------------------------------------SSG--EKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVV--HASGDASYSAGDSGDAAAQPAFTG---IKGKEGSALTEGAKEEGGEEVAKAVLEQE--ETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFG-------------SVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTD-LEPGVLMS------------AQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDAD-IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WV92-1", "uniprot_id": "E41L3_MOUSE", "id": "Q9WV92-1", "name": "Band 4.1-like protein 3", "aln": "----------------------------------MTTESGSDSESKPDQEAE--------------------PQEAAGPQGQAGAQPGPEPAGGN-------------------------------------------------------GSLNGEKQQPALEQFPEAAAHSTP------VKREIGDKDRDFA----------AAAAKQLEYQQFEDDKLSQR------------------SSSSKLSRSPLKIVKRPKSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGN-DYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPK--KFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVSENHEIYMKDSVSAAEVGTGQYATTKGISQTNLITTVTPEK-------------KAEEERVEEEDRRKKAE-EATPVTALRHEGK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDSERTDTAADGETSATESD------------------------------------------------------------------------------------------------------------------------------------------QEEDAEIKAQDLDKTQDELMKHQTNISELKRTFLETSTE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TALTN----------------------------------------------------------------------------------------------------EWEKRLSTSPVR------------------------------------------------------LAARQEDAPMIEPLVPEETKQ-----------------------------------------------SSG--EKLMDGSEILSLLESARKPTEFIGGVSSTTQSWVQKLETKTEPVEAEVESTPHPQPLSTEKVLQETILVEERHVMSVHASGDASHTARDEVDAAESTPTDRRHTGKGKEGSSVTEAAKEQRGEEVDQSAPEQE--QPATVSHE--EEQASTIRTSEGLEQKSHFESSTVRVESTSVG-------------SISPGGAKLEISTKEVPVVHTETKTITYESSQVDPGAD-LEPGVLMS------------AQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDAD-IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTP0-1", "uniprot_id": "E41L1_RAT", "id": "Q9WTP0-1", "name": "Band 4.1-like protein 1", "aln": "----------------------------------MTTETGPDSEVKKAQEET--------------------------------------------------------------------------------------------------------PQQPEAAAAVTTPVTPAGHSHPETNSNEKHLTQQDTR--------------PAEQSLDMEEKDYCEA------------DGLSERTTPSKAQKSPQKIAKKFKSATCRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDHDTEEHVG-NYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPK--GFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG-----------------AEFSRPASVSENHDAGPDGDKREDDAE------------SGGRRSEAEEGEVR-----TPTKIKELKPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QETTPR-------------------------------------------------------------------------------------------------------------------------------------------------HKQE-FLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDR-----------------------------------------------------------------------------------------------------------------------------------------DWERERRLP---------------------------------------------------------------------------------------------------------------------------------------------SSPASPSPKG------------------------TPEKAS-------------------------------------------------------------------------ERAGLREGSEEK---------------------------------------------------VKPPRPRAP------ESDTGD--------------------------------------------EDQDQERDAVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGGAFEDFSRSLPELDRDKSDSET--------EGLVFARDL-KGPSSQEDESGGIEDSPDRGACSTP----ELPQFESVKAETMTVSSLAIRKKIEPEAMLQSRVSTADST-QVDGGAPAAKDFMTTPPCITTET------------------ISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYG---------------ATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDED-VDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2H5-1", "uniprot_id": "E41L1_MOUSE", "id": "Q9Z2H5-1", "name": "Band 4.1-like protein 1", "aln": "----------------------------------MTTETGPDSEVKKAQEET--------------------------------------------------------------------------------------------------------PQQPEAAAAVTTPVTPAGHSHPETNSNEKHLTQQDTR--------------PAEQSLDMDDKDYSEA------------DGLSERTTPSKAQKSPQKIAKKFKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVG-NYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPK--GFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG-----------------AEFSRPASVSENHDAGPEGDKREDDAE------------SGGRRSEAEEGEVR-----TPTKIKELKPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QETTPR-------------------------------------------------------------------------------------------------------------------------------------------------HKQE-FLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDR-----------------------------------------------------------------------------------------------------------------------------------------DWDRERRLP---------------------------------------------------------------------------------------------------------------------------------------------SSPASPSPKG------------------------TPEKAS-------------------------------------------------------------------------ERAGLREGSEEK---------------------------------------------------VKPPRPRAP------ESDMGD--------------------------------------------EDQDQERDAVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGGAFEDFSRSLPELDRDKSDSET--------EGLVFAQDL-KGPSSQEDESGGLEDSPDRGACSTP----EMPQFESVKAETMTVSSLAIRKKIEPEAMLQSRVSAADST-QVDGGTPMVKDFMTTPPCITTET------------------ISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYG---------------ATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDED-VDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4G0-1", "uniprot_id": "E41L1_HUMAN", "id": "Q9H4G0-1", "name": "Band 4.1-like protein 1", "aln": "----------------------------------MTTETGPDSEVKKAQEEA--------------------------------------------------------------------------------------------------------PQQPEAAAAVTTPVTPAGHGHPEANSNEKHPSQQDTR--------------PAEQSLDMEEKDYSEA------------DGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVG-NYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPK--GFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG-----------------AEFSRPASVSENHDAGPDGDKRDEDGE------------SGGQRSEAEEGEVR-----TPTKIKELKPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QETTPR-------------------------------------------------------------------------------------------------------------------------------------------------HKQE-FLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDR-----------------------------------------------------------------------------------------------------------------------------------------DWERERRLP---------------------------------------------------------------------------------------------------------------------------------------------SSPASPSPKG------------------------TPEKAN-------------------------------------------------------------------------ERAGLREGSEEK---------------------------------------------------VKPPRPRAP------ESDTGD--------------------------------------------EDQDQERDTVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGSAFEDFSRSLPELDRDKSDSDT--------EGLLFSRDLNKGAPSQDDESGGIEDSPDRGACSTP----DMPQFEPVKTETMTVSSLAIRKKIEPEAVLQTRVSAMDNTQQVDGSASVGREFIATTPSITTET------------------ISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYG---------------ATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDED-VDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJ90-1", "uniprot_id": "A0AB32TJ90_DANRE", "id": "A0AB32TJ90-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MSERNSATKNPADGG-------------FTDHDSK--------------MSDEHRDTDD---------------------SSEKTPSRMSRSPQK-SKRPKTVPVKVLLLDGSAYESGVEKLCKGQVLLDMVCEHLNLLEKDYFGLSFSDTECQKNWLDPSKEIKKQIRVGPWHFSFAVKFYPPDPSQLIEDITRYYLCLQLREDILSGRLPCSFVTHALLGSYAIQAELGDYDPEEHGP-DYINEFRFAPNQTRELEERVMELHRTYRGMSPAEAEINFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCASGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRASKRLWKVCIEHHTFFRLVSPEPPPK--GFLVIGSKFRYSGRTQAQSRQASALIDRPAPQFERSISRRYLLSRSIDGESALGDTMDRL------SQHTSSEPVPSLPRDELDQDYLEPSLD------------QDLDQDHEQEEEQRLESDSTPSKTVELKREEAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPVDSKTELDQDLTPR-------------------------------------------------------------------------------------------------------------------------------------------------PKQEQFLDKPEDVLQKHQASINELKRALREPNSKLVHREKRLSGASSGSTPEKKSASEESLLIEKQDGCQ------------------------------------------------------------------------------RDLPLSKKDEKSRSPRVASLATGFNRETDDRVREKNIISVAKRTSTENILSPEKPLRNRAKSPALRYNHFQGINSLDEKAYDNGHSHDRPLSENVIHTNGCDTYATERLWGDKKYMGVTNIEHETTNQDLARYVERSFGEASPNAAMDKYMRDRYNESRCERQSYEKEPENTRATLLKQTSKADPKGKGSTIQRHDSTASDTSQSELKRIVPLKPERSKKLKDRKGAKLQGQPSERSISGSFDESEGINSKEDQVVFENALDTLSQSKNSATLESIGTFAKQDWASNYHNWETREYIRQSVQDRPQ-LRDLKNNIDHRLSIEQDQFLFDDPLFMFDFPTNSTFPAFDQIAPLYPPVKSQRARETRTKPITKSDSGNSLHKSSAMESSKRKSVEPLSTPAIHAEPQEEAQREPWERRLGSVSEDDPDPDTLYLKETHLGIERKCSSITVSSTSSLEAEVDFTVLMDFQTG-MEEFSRGMTELGEKDYSPDFGLSDRPTHPAFILGADPIYLPEERHVEVQRPVEKPKPVVEPKPPEERKPEPFVPKKAPRSVKAAQALRKDSTEQANAQSMRRESSESPPIHPLSRESSEIIASQALRKTEVKIETQP--------NGSEVTTTIMEIADPDHGISGMREAAYSMTERVSPVCQSFHRVNLGSLARDG----------SPLMVTENVTSATTTHVTKTVKGGYSETRIEKRIIITGDDD-VDQDQALAMAIKEAKQQHPDMLVTKAVVVRETESSTQDPHEESKS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V8R9-1", "uniprot_id": "EPB41_DROME", "id": "Q9V8R9-1", "name": "Protein 4.1 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MPAEIKPSAPAEPETP-----------------------------------------------------------------------TKSKPKSSSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAES--TNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKS--STLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAGAAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSG-RVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFG------KQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTERDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : :* *** : ::: *: ::. :* ***:*:***** :.*** * :.: .: .* ::* ******:*:** ******.****:* ** *****:*.* ****** :*:* **:*.: : ::::** :. ***::: :**::::. :*.:*: .:*****:*:******* *** **::* ****:.***:*:*:******.***:******* *:**:**.* *::********..:*::*:*** *:*****:** .: .* * .:**.:**.*****:: :.: :**..* *:*: * ***:*. : . : *: . : .: :. * : .. . . * . : . . . . : . . . .. : :. * ** :.* ***:*::* * .* :*:*:.*. **:** :*** * : : ::*: ", "identical_positions": 189, "similar_positions": 151, "identity": "9.69%" }, { "cls_id": "homologset.agr.FB:FBgn0010435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97943-1", "uniprot_id": "SCRB1_RAT", "id": "P97943-1", "name": "Scavenger receptor class B member 1", "aln": "------------------------------------------MGVSSRARWVALGLGVLGLLCAALGVIMILMVPSLIKQQVLKNVRIDP-SSLSFGMWKEIPVPFYLSVYFFEVVNPSEVLN-GQKPVVRERGPYVYREFRQKVNITFNDNDTVSYIENRSLRFQPDRSQGSESDYIVLPNILVLGGAVMMEDKPTSLKLLMTLGLVTMGQRAFMNRTVGEILWGYEDPFVNFLSKYFPDMFPI-KGKFGLFVGMNDSSSGVFTVFTGVQNFSKIHLVDKWNGLSEVNYWHSEQCNMINGTAGQMWAPFMTPESSLEFFSPEACRSMKLTYQ-ESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCP-----CRESGIQNVSTCRFGAPLFLSQPHFYNADPVLSEAVLGLNP-DPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPVVLPLLWFEQ-SGMMGGKTLNTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIIYQLRSQE-----------KCFLFWSG-----------------------SKKGSQDKEAMQAYSESLMSPAAKGTVLQEAKL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61009-1", "uniprot_id": "SCRB1_MOUSE", "id": "Q61009-1", "name": "Scavenger receptor class B member 1", "aln": "------------------------------------------MGGSSRARWVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDP-SSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLN-GQKPVVRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPI-KGKFGLFVGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYN-ESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCP-----CRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNP-NPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQ-SGAMGGKPLSTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIICQLRSQE-----------KCFLFWSG-----------------------SKKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTV0-1", "uniprot_id": "SCRB1_HUMAN", "id": "Q8WTV0-1", "name": "Scavenger receptor class B member 1", "aln": "------------------------------------------MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDP-SSLSFNMWKEIPIPFYLSVYFFDVMNPSEILK-GEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMFPF-KDKFGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYK-ESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCP-----CLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHP-NQEAHSLFLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAE-SGAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRTLWPTAAWSPPPAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLEGLGPSLGGGTGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z8R4-1", "uniprot_id": "A0A8M6Z8R4_DANRE", "id": "A0A8M6Z8R4-1", "name": "Scavenger receptor class B member 1", "aln": "------------------------------------------MVSQTTVSIVFLVLGGMALLF---GTVLVFVGPIIIDDQIVKNVEINPKNDLSYTMWKDIPVPFFMSVYFFHIVNPDEILK-GERPMVIQRGPYVYRENRWKDNITFHENHTVSYKEYRQYFFEESMSVGDESDVVTIPNMLVLGASVMMENMPFPVRLLLSTTFKTFNEGPFLTKPVGELMWGYDSKLVDFLNKYLPGMLPS-SGKFGLFADFNNSNTGLFTIFTGRDDIRKVHMVDSWNGLKNVDYWRSDQCNMINGTAGQMWPPFMTKETTMPFYSPDACRSMELVYQ-RPLVSSGIPVYRYVSPKTLFANGADFPPNEGFCP-----CRQSGLLNVSSCRHGSPTFISQPHFYNADPQLLDTVSGLSP-SEDEHGLFIDIHPETGVPVNVSVRLQLNLFLKKVSGISETGNIAEVVMPMLWFEE-SGYIDGPVLHTFRTNLVVLPKVMEYMQYIFIALGLAAILTAVILFLTDKK---------------VWKK-----------------------SSQTLTQAVSTRVYDNVNHSKQHPANETQAEKYNQSNTGKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0X0-1", "uniprot_id": "Q9W0X0_DROME", "id": "Q9W0X0-1", "name": "Scavenger receptor class B member 1", "aln": "MQLDDILHINNCKADCSSLSTTPNPKTDLVNMNGPKHKFCTKLSSTYLRKWWITIVVAAALIIG--GIVVACEFTVLIDAVVDRMVALRP-GAKTFGWWAKPPVEPRISLYIYNVTNADDFLSNGSKAIVDEVGPYVYSETWEKVNIVENDNGTLSYNLRKIYSFREDLSVGPEDDVVIVPNIPMLSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLWGYEDPLLKLAKDVVPKEQKLPYEEFGLLYGKNGTSSDRVTVNTGVDDIRRYGIIDNFNGRTHLPHWTTDACNTLAGTDGSIFPPHIDHDRILHVYDKDLCRLLPLVFEKEVMTSNEVPGYRFTPPEWVFADVDSHPDNMCFCPAGKPSCSPNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEKHQFFFDVQPKMGTTLRVRARIQINLAVSQVFDIKQVANFPDIIFPILWFEEGIDNLPDEVTDLMRFAEQVPPKIRVALIVGLCALGVILLLLSTFCLIRNSH------------------------------------------RQSTLHLEGSNYLATAQVDMNKKQNKDNQPARY---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .*: * :: . :*. : : * : * . :: * . *: :*:*::.: *..:.*. *.:. * : ***** * * **. ::* *:*: : *. . * * *.* : :**: :*..: : . ::* :: : : .*: .**:::***.. ::.: . .* :***: *.:.:. .*: ** ::: : ::*.:** ..: .* :: ** : ** *.::.*.: : : .:. : ** : * :: . . . :* **:..*. :**: .* * *** * .*: *** *:..:* ::* *** ** * * *: * . * :*:*::* * .:. .::*:.* :..* .: :..:: :::*:*** : . : . : : *:: : .** :* . : : .. . . ", "identical_positions": 105, "similar_positions": 174, "identity": "17.36%" }, { "cls_id": "homologset.agr.FB:FBgn0010438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28042-1", "uniprot_id": "SSBP_RAT", "id": "P28042-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MFRRPVLQVFRQFVR---QESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDNEAYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIADNIIFLSDQAREKPLNG--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYR0-1", "uniprot_id": "SSBP_MOUSE", "id": "Q9CYR0-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MFRRPVLQVFRQFVR---HESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDSEVYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIAGKKLVVHSVSG-CSLEGLA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04837-1", "uniprot_id": "SSBP_HUMAN", "id": "Q04837-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MFRRPVLQVLRQFVR---HESETTTSLVLERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSEVYQLGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLSDQTKEKE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5I7-1", "uniprot_id": "SSBP_DANRE", "id": "B8A5I7-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "-----MLRNASAQILKQFVR---HRT-TDASLTLEKSINKVQILGRVGQDPVMRQVEGRNPVTIFSMATNEMWRSGEGEPVGAGDVTQKTTWHRISVFKPGLRDVAYQYVKKGSRIFVEGKLDYGEYVDKNNVRRQATTIIADNIVFLSENLRDQ------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54622-1", "uniprot_id": "SSBP_DROME", "id": "P54622-1", "name": "Single-stranded DNA-binding protein, mitochondrial", "aln": "MQHTRRMLNPLLTGLRNLPARGATTTTAAAPAKVEKTVNTVTILGRVGADPQLRGSQ-EHPVVTFSVATHTNYK------YENGDWAQRTDWHRVVVFKPNLRDTVLEYLKKGQRTMVQGKITYGEITDQQGNQKTSTSIIADDVLFFRDANN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32445-1", "uniprot_id": "RIM1_YEAST", "id": "P32445-1", "name": "Single-stranded DNA-binding protein RIM1, mitochondrial", "aln": "-----MFLRTQARFFHATTK--------------KMDFSKMSIVGRIGSEFTEHTSANNNRYLKYSIAS-------------QPRRDGQTNWYNITVFNEPQINFLTEYVRKGALVYVEADAANYVFERDDGSKGTTLSLVQKDINLLKNGKKLEDAEGQENAASSE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :: : .. : ::**:* : : .: :*:*: :* *:.: **. : :*::** ::.. .:. : : ::: . .. . ", "identical_positions": 12, "similar_positions": 44, "identity": "7.19%" }, { "cls_id": "homologset.agr.FB:FBgn0010441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G1H3-1", "uniprot_id": "A0A8I6G1H3_RAT", "id": "A0A8I6G1H3-1", "name": "Interleukin-1 receptor-associated kinase 4", "aln": "---------------------MSKPLTP--STYVRSLNVGILRKLSDFIDPQE---GWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTG-KSPTCELLFDWG-TTNCTVGDLVDLLIQIELFAPATLLLPDA-----------------------------VPQAVHSLPPREAATVAQAHRPCQEKNRTTVTPA--------LAQKLEPSCELPDSSSPGHQ--SVEFSDTRFHSFSFYELKSITNDFDERPVSIGGNRMGEGGFGVVYKGCVNNTTVAVKKLGAMVE--ISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTP---PLSWHMRCKIARGAANGIRFLHEN---HHIHRDIKSANILLDQDFTAKISDFGLARASAKLA---QTVMTSRIVG----TTAYMAPEALR-GEITPKSDIYSFGVVLLELITGLAAVDEN-REPQLLLDIKEEIEDKE--------------------------KTIEDCTDEKMSDADPASVEAMYSVASQCLHEKKNRRPDIAKVQQLLQETSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4K2-1", "uniprot_id": "IRAK4_MOUSE", "id": "Q8R4K2-1", "name": "Interleukin-1 receptor-associated kinase 4", "aln": "---------------------MNKPLTP--STYIRNLNVGILRKLSDFIDPQE---GWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTG-KSPTCELLFDWG-TTNCTVGDLVDLLVQIELFAPATLLLPDA-----------------------------VPQTVKSLPPREAATVAQTHGPCQEKDRTSVMP----------MPKLEHSCEPPDSSSPDNR--SVESSDTRFHSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNTIVAVKKLGAMVE--ISTEELKQQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTP---PLSWHTRCKVAQGTANGIRFLHEN---HHIHRDIKSANILLDKDFTAKISDFGLARASARLA---QTVMTSRIVG----TTAYMAPEALR-GEITPKSDIYSFGVVLLELITGLAAVDEN-REPQLLLDIKEEIEDEE--------------------------KTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEMSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWZ3-1", "uniprot_id": "IRAK4_HUMAN", "id": "Q9NWZ3-1", "name": "Interleukin-1 receptor-associated kinase 4", "aln": "---------------------MNKPITP--STYVRCLNVGLIRKLSDFIDPQE---GWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTG-KSPTSELLFDWG-TTNCTVGDLVDLLIQNEFFAPASLLLPDA-----------------------------VPKTANTLPSKEAITVQQKQMPFCDKDRTLMTP----------VQNLEQSYMPPDSSSPENK--SLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVD--ITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTP---PLSWHMRCKIAQGAANGINFLHEN---HHIHRDIKSANILLDEAFTAKISDFGLARASEKFA---QTVMTSRIVG----TTAYMAPEALR-GEITPKSDIYSFGVVLLEIITGLPAVDEH-REPQLLLDIKEEIEDEE--------------------------KTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RYC8-1", "uniprot_id": "B2RYC8_RAT", "id": "B2RYC8-1", "name": "Interleukin-1 receptor-associated kinase 3", "aln": "---------------MAGPCGARGTLSP--HSLLFDLPPALLGELCTILDSCDGPLGWRGLAERLSN-------SWLDVRHIEKYVHQG-KSGTRELLWSWA-QKNKTIGDLLQVLHEMGHQRAIHLIMNYG-----------------------------VNWTPPVQTHHELRFPNLPPNSKPVCRESDPGP-------------LELANVTVDNVLVPEH--NERGVVLHKTPISFQSILEGTKHFHK------DFLIGEGEIFEVYRVEIRNQTYAVKLFKQEKT--MQLKKHWKRFLSELEVLLLFNHPHILELAAYFTEMEKLCLVYPYMSNGTLFDRLQCTNGTT---PLSWHVRISVLIGIAKAIQCLHNTRPCAVICGNISSANILLDDQFQPKLTDFAAAHFRPHLE---QQSSTINMTGSGRKHLWYMPEEYIRQGRLTIKTDVYSFGIVIMEVLTGCKVVLDD-PKHVQLRDLLMELVEKRGL------------------------DSCLSFLDRKIPPCPRNFSAKLFSLAGQCVATRAKLRPTMDEVLNTLESTQPSLY-FAEDPPTSLKSFRCPSPLFLDNVPSIPVEDDENQNNYPVPPKEALRTDRVTQKTPFECSQSEVTFLGLDRNKGNRGSEAACNMPSSSCEECWCPELAEASQDLRPTVISLGSSWEVPGYSYGSKPMEKRCSSGLFCSEHEQSKRQ-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4B2-1", "uniprot_id": "IRAK3_MOUSE", "id": "Q8K4B2-1", "name": "Interleukin-1 receptor-associated kinase 3", "aln": "---------------MAGRCGARGALSP--QLLLFDLPPALLGELCGILDSCDGPLGWRGLAERLSN-------SWLDVRHIEKYVNQG-KSGTRELLWSWA-QKNKTIGDLLEVLQDMGHQRAIHLIINYG-----------------------------VSWTPSVQTHHELPFPSFPPEVKHACRENDPGP-------------LEPANVTVDNVLVPEH--NEKG-TLQKTPISFQSILEGTKHFHK------DFLIGEGEIFEVYRVDIRNQAYAVKLFKQEKK--MQLKKHWKRFLSELEVLLLFRHPHILELAAYFTETEKLCLVYPYMSNGTLFDRLQCTNGTT---PLSWHVRISVLIGIAKAIQYLHNTQPCAVICGNVSSANILLDDQLQPKLTDFAAAHFRPNLE---QQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCKVVLDD-PKHVQLRDLLMELMEKRGL------------------------DSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLESTQPSLY-FAEDPPTSLKSFRCPSPLFLDNVPSIPVEDDENQNNHSVPPKEVLGTDRVTQKTPFECSQSEVTFLGLDRNRGNRGSEADCNVPSSSHEECWSPELVAPSQDLSPTVISLGSSWEVPGHSYGSKPMEKRCSSGLFCSEHEQSKKQ-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y616-1", "uniprot_id": "IRAK3_HUMAN", "id": "Q9Y616-1", "name": "Interleukin-1 receptor-associated kinase 3", "aln": "---------------MAGNCGARGALSA--HTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSS-------SWLDVRHIEKYVDQG-KSGTRELLWSWA-QKNKTIGDLLQVLQEMGHRRAIHLITNYG-----------------------------AVLSPSEKSYQEGGFPNILFK--------------------------ETANVTVDNVLIPEH--NEKG-ILLKSSISFQNIIEGTRNFHK------DFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKK--MQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTA---PLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLE---HQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDD-PKHIQLRDLLRELMEKRGL------------------------DSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLY-FAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JYX9-1", "uniprot_id": "A0A0G2JYX9_RAT", "id": "A0A0G2JYX9-1", "name": "Interleukin-1 receptor-associated kinase 1", "aln": "---------------MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEP-ADWCQFAALIVR-------DQTELRLCERSEQR-----TASVLWPWI-NRNARVADLVHILTHLQLLRARDIITAWHPPASV-----LPPSTGAPRPSSISAGSETEDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLSDSLGPPLQSSAPSSIKQPSPESPVS--GLQRARPSPFCWPFCEISQGTCNFSE------ELRIGEGGFGCVYRAVMRNTTYAVKRLKEEAD--LEWTVVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGFYCLVYGFLPNGSLEDQLHLQTQACS--PLSWPQRLDILLGTARAIQFLHQDSP-SLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGANPSQSSTVARTCTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEVGVTLKSTQPTLWMGVATDAWTAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAVP---PWKLEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPDSHPSPVSFREASCTQGGTTRESSLRSGPGFQPTTMEGSSMGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKRKRPEESDEFQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62406-1", "uniprot_id": "IRAK1_MOUSE", "id": "Q62406-1", "name": "Interleukin-1 receptor-associated kinase 1", "aln": "---------------MAGGPGPGEPVVPGAQHFLYEVPPWVMCRFYKVMDALEP-ADWCQFAALIVR-------DQTELRLCERSEQR-----TASVLWPWI-NRNARVADLVHILTHLQLLRARDIITAWHPPAPV-----VPPSTAAPRPSSISAGSEAGDWSPRKLQSSASTFLSPAFPGSQTHSESELLQVPLPVSLGPPLPSSAPSSTK-SSPESPVS--GLQRAHPSPFCWPFCEISQGTCNFSE------ELRIGEGGFGCVYRAVMRNTTYAVKRLKEEAD--LEWTMVKQSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACS--PLSWPQRLDILLGTARAIQFLHQDSP-SLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEGLQAGP---PWELEVAGHGSPSPQENSYMSTTGSAQSGDEPWQPLVVTTRAPAQAAQQLQRSPNQPVESDESVPGLSATLHSWHLTPGSHPSPASFREASCTQGGTTRESSVRSSPGFQPTTMEGSPTGSSSLLSSEPPQIIINPARQKMVQKLALYEEGVLDSLQLLSSGFFPGLDLEPEKSQGPEESDEFQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51617-1", "uniprot_id": "IRAK1_HUMAN", "id": "P51617-1", "name": "Interleukin-1 receptor-associated kinase 1", "aln": "---------------MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEP-ADWCQFAALIVR-------DQTELRLCERSGQR-----TASVLWPWI-NRNARVADLVHILTHLQLLRARDIITAWHPPAPL-----PSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTK-PGPESSVS--LLQGARPFPFCWPLCEISRGTHNFSE------ELKIGEGGFGCVYRAVMRNTVYAVKRLKENAD--LEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACP--PLSWPQRLDILLGTARAIQFLHQDSP-SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQD-RQGPEESDEFQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O43187-1", "uniprot_id": "IRAK2_HUMAN", "id": "O43187-1", "name": "Interleukin-1 receptor-associated kinase-like 2", "aln": "-----------------------------MACYIYQLPSWVLDDLCRNMDALS-EWDWMEFASYVIT-------DLTQLRKIKSMERVQGVSITRELLWWWG-MRQATVQQLVDLLCRLELYRAAQIILNWKPAPEIRCPIPAFPDSVKPEKPLAASVRKAEDEQEEGQPVRMATFPGPGSSPARAHQPAFLQPPEEDAPHSLRSDLPTSSDSKDFSTSIPKQE-KLLSLAGDSLFWSEADVVQATDDFNQ------NRKISQGTFADVYRGHRHGKPFVFKKLRETAC--SSPGSIERFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSD---PLPWPQRVSICSGLLCAVEYLHGL---EIIHSNVKSSNVLLDQNLTPKLAHP-MAHLCPVNK---RSKYTMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNN-RSPVYLKDLLLSDIPSSTASLCSRKTG---------VENVMAKEICQKYLEKGAGRLPEDCAEALATAACLCLRRRNTSLQEVCGSVAAVEERLRGRE------TLLPWSGLSEGTGSSSNTPEETDDVDNSSLDASSSMSVAPWAGAATPLLPTENGEGRLRVIVGREADSSSEACVGLEPPQDVTETSWQIEINEAKRKLMENILLYKEEKVDSIELFGP---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05652-1", "uniprot_id": "KPEL_DROME", "id": "Q05652-1", "name": "Serine/threonine-protein kinase pelle", "aln": "MSGVQTAEAEAQAQNQANGNRTRSRSHLDNTMAIRLLPLPVRAQLCAHLDALD---VWQQLATAVKL-------YPDQVEQISSQKQRG-RSASNEFLNIWGGQYNHTVQTLFALFKKLKLHNAMRLIKDYVS-------------------------EDLHKYIPRSVPTISELRAAPDSSAKVNNGPPFPSSSGVSNSNNNRTSTTATEEIPSLESLGNIHISTVQRAAESLLEIDYAELENATDGWSP------DNRLGQGGFGDVYRGKWKQLDVAIKVMNYRSPNIDQKMVELQQSYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDFGLVREGPKSL------DAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTG-RQVTDRVPENETKKNLLDYVKQQWRQN---------------------RMELLEKHLAAPMG-KELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFEPFVTD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : :*. . * :* : .:. . : ..* * : : *. :: . :: .: * : :.:* : **: . ..* : : *:: * ::: . .: .::* : .*:* :* .*.* * : * .: ** * .:..:*:***. : .*: . .: . *:. : . .:: * :* *:*: * ::* : :: . . . . * : .: ", "identical_positions": 37, "similar_positions": 93, "identity": "4.86%" }, { "cls_id": "homologset.agr.FB:FBgn0010452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75325-1", "uniprot_id": "LRRN2_HUMAN", "id": "O75325-1", "name": "Leucine-rich repeat neuronal protein 2", "aln": "-MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPR------------SSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDS-RWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWAN--ATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGR----RYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRALGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVGGRRPLPPAWAFWGWSAPSVRVVSAPLVLPWNPGRKLPRSSEGE---------TLLPP-----------LSQNS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZAV8-1", "uniprot_id": "D3ZAV8_RAT", "id": "D3ZAV8-1", "name": "", "aln": "-MRLLVAALLLSWAASTNTAVPVVPWRVPCPPQCACQIRPWYTPR------------SSYREATTVDCNDLFLTAVPPGLPAGTQTLLLQSNSISRIEQTELGYLANLTELDLSQNSFSDARDCDFQALPQLLSLHLEENQLSRLEDHSFAGLTRLQELYLNHNQLCRISPRAFEGLGNLLRLHLNSNLLRTIDS-RWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMSLREISDYALEGLQSLESLSFYDNQLAQVPKRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWAN--ATGTHVRFIEPQSTLCAEPPDLQRRPVREVPFREMTDHCLPLISPRSFPSSLQVASGESLVLHCRALAEPEPEIYWVTPAGVRLTPARSGR----KYRVFPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVVGHAPFQPGRDKGPGLELHVQETHPYHILLFWAPPPNIVSTNLTWSSAASLRDHETTALARLPRGTHRYNITRLLPATEYWACLQVAFADAHTQLACVWARTKEASPCHRALGDRPGLIAILALAVLLLAAGLAAHLGRGQSKQRVG-EKPLLPVWAFWGWSAPSVRVVSAPIVLPWNPGRKQPRCQMGKQCHHHCLNIAEAPPGLSSREITRTTLHQTGRDLGQMPARNAALIDPHA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PFH7-1", "uniprot_id": "M9PFH7_DROME", "id": "M9PFH7-1", "name": "", "aln": "MQRNMMIAFVGIWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEG-LFPWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNP-AMMGCTHADPRKQALIGALLVGSAATITALALVLYRCRHKIRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHSTFPNTYTAPHHPGATHHYGMCPMPVN---DLGAIDPQQKFQQLVVPTATMISEKKLNNNKALVSQGAIDDS-ASFVLHMKSATMGRDVHQQNPQLNHYTKPQFLSATATVGDSC-YSYADVPMVHGAPLGGPNQPQLRLTQEHFKQRELYDQEMGSEILDHNYIYSNTHYSMPLEQLGRSKTPTPPPMPPALPLRNGLCATTGRRSFQQKSASQKQQQNNN----------TLRQFTHXSSTYRRRQLSIYA---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: .:: * :. .* .. . *** * *: .. . .. : .:..*.: . : * * *.** : : * :.* :* *:.*.:*.:.: : * .*. : *:*. **::.*.: :*: * ::** *..*:: : *:**.**.:* *:*:.* * :: . *: :*.* *::* *.:::* *: * .* * * * .**:**. :: ***.*. *.: **:* ::* .*.:: *: *.*.:* :: :. * * .: :**.* :*. .* : . *: : :* *:::.* * :: *: *.*:: ::*: ***::* : : . :** :.* **: *** : * : ..... : .. ** * *: .:*.: * . . ::: :* *.*. ::. . .* . . :* . .*: ..* . : : . *. :. :: . . *::: ..:. .... .: * . : . . * *: : : . : :..* : * .:: . :: : :: .* :: : :::: *. * * . :* :: :. . .**. *: : .:* : .. . : : . * .** . * . . * * ", "identical_positions": 138, "similar_positions": 254, "identity": "17.9%" }, { "cls_id": "homologset.agr.FB:FBgn0010453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LQL8-1", "uniprot_id": "A0ABK0LQL8_RAT", "id": "A0ABK0LQL8-1", "name": "Protein Wnt", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MR-------------------LWDSPCCLTGREV------------------------------LTPFPGPGTAAAPAQAGAHLKQCDLLKLSRWQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEG--RTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWVPAKPGGPAKG---LAPRPVDLVYMEDSPSFCRPSKYSPGTAGRVCSRDTSCSSLCCGRGYDTQSRMVAFSCHCQGSMRMLGRSLMTEGPRRNHSDPRPFSGMTLLTKETHPQLVRRQKQIENCFPLKEDVFLGNPRRPSPLGPLILFCFEGTRQEGSLGELGNSNTQIYDLYPDSMARRARGEGGSKMNLKLRLRLTDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35468-1", "uniprot_id": "WNT9B_MOUSE", "id": "O35468-1", "name": "Protein Wnt-9b", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MRPAPALALAALCLLVLPAAAAAAAYFGLTGREV------------------------------LTPFPGLGTAAAPAQAGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEG--RTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWAPAKPGGPAKG---LAPRPGDLVYMEDSPSFCRPSKYSPGTAGRVCSRDSSCSSLCCGRGYDTQSRMVVFSCHCQ----------------------------------------------------------------------VQWCCYVECQQCAQQELVYTCKR--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14905-1", "uniprot_id": "WNT9B_HUMAN", "id": "O14905-1", "name": "Protein Wnt-9b", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MRPPPALALAGLCLLALP--AAAASYFGLTGREV------------------------------LTPFPGLGTAAAPAQGGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEG--RMGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKG---LAPRSGDLVYMEDSPSFCRPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQ----------------------------------------------------------------------VQWCCYVECQQCVQEELVYTCKH--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZF63-1", "uniprot_id": "D3ZF63_RAT", "id": "D3ZF63-1", "name": "Protein Wnt", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MLDGSLLARWLAAAFGLTLLLAALRPSAAYFGLTGSEP------------------------------LTILP--LTLETEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETSLKVGSTTNEATGEAGAISPPRGRASGSGGGDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQ----------------------------------------------------------------------VRWCCYVECRQCTQREEVYTCKG--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5M2-1", "uniprot_id": "WNT9A_MOUSE", "id": "Q8R5M2-1", "name": "Protein Wnt-9a", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MLDGSLLARWLAAAFGLTLLLAALRPSAAYFGLTGSEP------------------------------LTILP--LTLETEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETSLKVGSTTNEATGEAGAISPPRGRASGSGGGDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQ----------------------------------------------------------------------VRWCCYVECRQCTQREEVYTCKG--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14904-1", "uniprot_id": "WNT9A_HUMAN", "id": "O14904-1", "name": "Protein Wnt-9a", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEP------------------------------LTILP--LTLEPEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQ----------------------------------------------------------------------VRWCCYVECRQCTQREEVYTCKG--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40589-1", "uniprot_id": "WNT4_DROME", "id": "P40589-1", "name": "Protein Wnt-4", "aln": "MPSPTGVFVLMILTHLSFGLGQVRNEDQLLMVGQNGDLDSSNPAIHHQQHQQHQQHQQHQQHQSNHNLNNGNMNSTILNTLMGNNAGQVVNSSPGGGGSMINQLGSSTSSVPSVIGGGVGSVGNPWHSAVGLGVPGNGMGLPSSHGLGGNMGSHPHGHALAGLAKLGIIVPGGQGLPGNLGYGGTMLNGGGVGGAAGMGLGIGSNTNNMDMQQGLYNEHFISEHTVMAVFTSQGQVGGPCRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKP---QQSQYTTLYYLETSPSYCAVTKD------RQCLHPDNCGTLCCGRGYTTQVVKQVEKCRCRFN--------------------------------------------------------------------NGRCCQLICDYCQRLENKYFCK---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :. . : * : * *.: **::.*:. ** :* :. .*: *** :****::* : .:::: :*****::*:::*.:**::*:**: *** :*:*. .. : :*** *.****:..:. .**. : .. * :. *:. **::.:.: : .**********:::***:::: *. .. *: :*: ::: .. .. .: * ::: ***:* : * * : .* ::*****: ** . *:*: * * . ", "identical_positions": 85, "similar_positions": 105, "identity": "13.1%" }, { "cls_id": "homologset.agr.FB:FBgn0010470", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y680-2", "uniprot_id": "FKBP7_HUMAN", "id": "Q9Y680-2", "name": "Peptidyl-prolyl cis-trans isomerase FKBP7", "aln": "MPKTMHFLFRFIVFFYLWGLFTAQRQKKE-ESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQ----------DAVLEDIFKKNDHDGDGFISPKE------------------------------YNVYQHDEL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54998-1", "uniprot_id": "FKBP7_MOUSE", "id": "O54998-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP7", "aln": "----MNLLFRLAVFLSLWCCSDAQGQTKE-ESTEEVKIEVLHRPENCSKTSRKGDLLNAHYDGYLAKDGSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIPPSFAYGKEGYAEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDNDRQLSKAEIELYLQKDFEKDANPRDKSYQ----------KAVLEDIFKKNDHNGDGFISPKE------------------------------YNVHQHDEL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5N3-1", "uniprot_id": "A0A8I6A5N3_RAT", "id": "A0A8I6A5N3-1", "name": "peptidylprolyl isomerase", "aln": "----MNLLFRLSVFLGLWVCSGAQGQTKE-ESTEEVKIEVLHRPENCSKTSRKGDLLNAHYDGYLAKDGSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIPPSLAYGKEGYAEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDNDRQLSKAES-FTYRRTLKKTQNPVTSHIR----------RRFWKISLRKMTTMETASFLPRNTTCTNMTSFKFAPSLSLAAHTPRFKHREPLFSVWPLSRMRRYSCPSINIILV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZZ60-1", "uniprot_id": "Q7ZZ60_DANRE", "id": "Q7ZZ60-1", "name": "peptidylprolyl isomerase", "aln": "--MFLRFLFYFCLILSLQALYPFITIIRANETNEDVKIEVTFLPENCSQKAKRGDMLNAHYDGFLAKDGSQFYCSRTTEKGHPHWFVLGVGNIIKGLDVALQDMCPGEKRKVTIPPSLAYGEKG--NGPVPPNATVIFEVELLHISRGPRSIEAFKEMDVDNNKELTKEEIKEYLKMEAKKLQTHKDESYF----------DDVVADVFLKNDHDADGTLSLKE------------------------------YNIYNHDEL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NWM8-1", "uniprot_id": "FKB14_HUMAN", "id": "Q9NWM8-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP14", "aln": "----MRLFLWNAVLT-LFVTSLIGALIPE----PEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKG--KIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKK----EFEKHGAVVN------ESHHDALVEDIFDKEDEDKDGFISAREFT-------------------------------YKHDEL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59024-1", "uniprot_id": "FKB14_MOUSE", "id": "P59024-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP14", "aln": "----MRFFLWNAILA-LWVTVLSGALIPE----PEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKRKLTVPPALGYGKEGKG--KIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWRLSKHEVKVYLQK----EFEKHGAVVN------ESHHDALVEDIFDKEDEDKDGFISAREFT-------------------------------YVHDEL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNA7-1", "uniprot_id": "A0ABZ3NNA7_RAT", "id": "A0ABZ3NNA7-1", "name": "peptidylprolyl isomerase", "aln": "----MRFFLWNANLT-LWVTVLSGALIPE----PEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKRKLTIPPALGYGKEGKG--KIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKHELLQRCAPGCGCPFMDHSGSCR------VVPVALTSCYVLPQWSVELSVVKHVLEIG-------------------------------AK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4K7C5-1", "uniprot_id": "A0A0B4K7C5_DROME", "id": "A0A0B4K7C5-1", "name": "peptidylprolyl isomerase", "aln": "------MSKSNLVISCLLLVAISNSLVRA----QDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRD--QPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGN-VIPPKATLLFDVELINIGNAPPTTNVFKEIDDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHEDKDKNGFISHDEFSG------------------------------PKHDEL-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * ::*:** * * :.:: ** : ** * * **. * .: : :* * ** . :** * .: .** *****: :** :.**.:* :**.:*::*:::* : ..* : : *:::* : : .*:: * : : : ", "identical_positions": 44, "similar_positions": 50, "identity": "15.94%" }, { "cls_id": "homologset.agr.FB:FBgn0010473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5H6-1", "uniprot_id": "TUTLA_RAT", "id": "P0C5H6-1", "name": "Protein turtle homolog A", "aln": "----------------------------------------------------------------------------------------------------------MIWCLRLTILSLILSQGADGRRKP----EVVSVVGRAGESAVLGCDLLPPAGR------PPLHVIEWLR----FGFLLPIFIQFGLYSPRIDPDYVGRVR------LQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVALGSPQPYVTWKFRGQDLGKGQGQVQVRNG-TLWIRRVERGSAGDYTCQASSTEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQDVSLACRAEAYPANLTYSWFQDRINVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFPHPPSASAYLTVLYPAQVTVMPPETPLPIGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLVIALGNEDALGEYSCTPYNSLGTAGSSPVTRVLLKAPPAFIDQPKEEYFQEVGRDLLIPCSARGDP---PPIVSWA-KVGRGLQGQAQ---VDSNNSLILRPLTKEAHGRWECSARNAVAHVTISTNVYVLGTSPHVVTNVSVVPLPKGANVSWEPGFDGG--YLQRFSVWYTPLAKRPDRAHHDWVSLAVP-MGATHLLVPGLQAYTQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAV------------PRLPPTEMPPPLSPPRGLVAVRTPRGVLLHWDPPELIPERLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNIANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAACLMNRRRAARRHRKR-----------------LRQDPP-----------------------------LIFSPRGRS---GPHSAPGSDSPDSVTKFKLQGSPVPSLRQSLLWGEPARPPSPHPDSPLGR---GPLP-LEPICRGPDGRFVMGPTVAP------PQEKLCLERSEPRTSAKRLAQSLDCSSSSPSGVPQPLCITDISPVGQPPAAMPSPLPG------------------------------------------------------------------------------------------------------PGPLLQYLSLP------------FFREMNVDGD-------------------------WPPLEEPTPASP---------------------PDFMGSHPCPTSSFLPPPDSPPTNLRAVLPGTLMGVG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSSEPP-----------------------------------------------------------------YTALADWTLRERVLPG---------------------------------------------------------------------------------------------------------------------------------------------------------LLSAAPRGSLTSQSSGRGSASFLRPPS--------------------TAPSAG--------------------------------------------------------------------------------------------------------------------------GSYLSPAPG---------------DTSSWASGPERWPRRE-------HVVTVSKRRNTSVDENYEWDS----------------------------------------------EFPGDMELLETWHPGLASSRAHPELEPELGVKTPEKS-CLLNTTHAPGPEARCAALREEFLAFRRRRDATRARLPVCQQSISYPEQATLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05BQ1-1", "uniprot_id": "TUTLA_MOUSE", "id": "Q05BQ1-1", "name": "Protein turtle homolog A", "aln": "----------------------------------------------------------------------------------------------------------MIWCLRLTVLSLIISQGADGRRKP----EVVSVVGRAGESAVLGCDLLPPAGH------PPLHVIEWLR----FGFLLPIFIQFGLYSPRIDPDYVGRVR------LQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVARGSPQPYVTWKFRGQDLGKGQGQVQVQNG-TLWIRRVERGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEAYPANLTYSWFQDGVNVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLHPPSASAYLTVLYPAQVTVMPPETPLPTGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLIIALGNENALGEYSCTPYNSLGTAGPSPVTQVLLKAPPAFIDQPKEEYFQEVGRELLIPCSARGDP---PPIVSWA-KVGRGLQGQAQ---VDSNNSLVLRPLTKEAQGRWECSASNAVARVTTSTNVYVLGTSPHVVTNVSVVPLPKGANVSWEPGFDGG--YLQRFSVWYTPLAKRPDRAHHDWVSLAVP-IGATHLLVPGLQAHAQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAA------------PGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELIPGRLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNVANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAACLMNRRRAARRHRKR-----------------LRQDPP-----------------------------LIFSPRGKS---GSHSAPGSGSPDSVTKFKLQGSPVPSLRQSLLWGEPARPPSPHPDSPLGR---GPLP-LEPICRGPDGRFVMGPTVAP------SQEKLCLERSEPRTSAKRLAQSFDCSSSSPSGVPQPLCITDISPVGQPLAAVPSPLPG------------------------------------------------------------------------------------------------------PGPLLQYLSLP------------FFREMNVDGD-------------------------WPPLEEPTPAPP---------------------PDFMDSQPCPTSSFLPPPDSPPANLRAVLPGTLMGVG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSSEPP-----------------------------------------------------------------YTALADWTLRERVLPG---------------------------------------------------------------------------------------------------------------------------------------------------------LLSAAPRGSLTSQSSGRGSASFLRPPS--------------------TAPSAG--------------------------------------------------------------------------------------------------------------------------GSYLSPAPG---------------DTSSWASGPERWPRRE-------HVVTVSKRRNTSVDENYEWDS----------------------------------------------EFPGDMELLETWHPGLASSRTHPELEPELGVKTPEES-CLLNPTHAAGPEARCAALREEFLAFRRRRDATRARLPAYQQSISYPEQATLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2J2-1", "uniprot_id": "TUTLA_HUMAN", "id": "Q9P2J2-1", "name": "Protein turtle homolog A", "aln": "----------------------------------------------------------------------------------------------------------MVWCLGLAVLSLVISQGADGRGKP----EVVSVVGRAGESVVLGCDLLPPAGR------PPLHVIEWLR----FGFLLPIFIQFGLYSPRIDPDYVGRVR------LQKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNG-TLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDP---PPVVSWT-KVGRGLQGQAQ---VDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGG--YLQRFSVWYTPLAKRPDRMHHDWVSLAVP-VGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAA------------PGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELVPKRLDGYVLEGRQGSQGWEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPSNTANVSTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAGCLLNRRRAARRRRKR-----------------LRQDPP-----------------------------LIFSPTGKS---AAPSALGSGSPDSVAKLKLQGSPVPSLRQSLLWGDPAGTPSPHPDPPSSR---GPLP-LEPICRGPDGRFVMGPTVAA------PQERSGREQAEPRTPAQRLARSFDCSSSSPSGAPQPLCIEDISPVAPPPAAPPSPLPG------------------------------------------------------------------------------------------------------PGPLLQYLSLP------------FFREMNVDGD-------------------------WPPLEEPSPAAP---------------------PDYMDTRRCPTSSFLRSPETPPVSPRESLPGAVVGAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATAEPP-----------------------------------------------------------------YTALADWTLRERLLPG---------------------------------------------------------------------------------------------------------------------------------------------------------LLPAAPRGSLTSQSSGRGSASFLRPPS--------------------TAPSAG--------------------------------------------------------------------------------------------------------------------------GSYLSPAPG---------------DTSSWASGPERWPRRE-------HVVTVSKRRNTSVDENYEWDS----------------------------------------------EFPGDMELLETLHLGLASSRLRPEAEPELGVKTPEEG-CLLNTAHVTGPEARCAALREEFLAFRRRRDATRARLPAYRQPVPHPEQATLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDD3-1", "uniprot_id": "A0A8N7TDD3_DANRE", "id": "A0A8N7TDD3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MVQKKLWLLNVSVAVALSLLRLTLS----TEPVVQGRVGGFAELGCSLTPPSEGATTPNLFPLHVVEWVR----LGYNVPILIKFGSYTPRVHPNYKGRVS------LSRGASLMVEKLTLEDEGWFECRILLLDRTSDEFQN--GTWNFLSITAPPVFIKTPPPFLEVLLGESLTLHCDAHGNPKPTIIWRKYLSAAEK-QEEIQVLNE-TLSLSKVTRETAGIYKCHVSNSEGNLTHSTQLQVKGPPIIIIAPEDTTMNMSQDAVLQCQAEAYPSNLTYEWWKQGQNVYHIEILKSRVKILVDGTLLISALIPDDSGNYTCRPTNGLMTPPAASAYLTVKHPARVVRMPRETYLPMGMGGKIPCPVQAEPPMLYVNWTKDGASLNLEQYPGWMVNSEGSVFITAANDDAVGMYTCTAYNSYGTMGQSEPTKVILKDPPSFRVSPRAEYLQEVGRDLVIPCQSQGDP---SPNITWI-KVGPAPRSPFT---VLSNGSLFLRPLSKDHQGTWECLASNRVATVSVATTILVLGTSPHAVTSVSVDPGIGQANVSWEAGFDGG--YTQRFTVWVKPTVRG----KHEWASIPVP-TSKTSLLVTSLQPATSYQFSVLAQNKLGSGPFSEIVTIKTLAPPTESPT----------------VLTTMAVLSPPTLLSANRTSLGVLLQWVPPLEES--LTSFALQAKRGKGEWVTIDREIAVNMTELIVQGLVKDSKYELRLLSCQDKLVSVPSDSVLISTEGMEMYPAAPSLLAFVPEPLLAGVIGGVCFLFVAIILSLVTACVMNSKRRQRRQKKRDDIPSAFQKSSAPQANSPSDSPD-----------------------------SLLKLKLCPPLNFFPNSSSSDRSDRSSFDKASRSEYQDQKKQLLSSSSPPPHYTQFESHFGG-TPSPTPAIESISRSPDGRFIIQPDLENFKKNLKKEFPQSPSRGSGRGSSNGSFKESNQSNSARSETNAQTEMPSALTVDHPHLERPPHSPGRVRAMARNFSRHGCFYSDDEHGGSEALLERASFYSDCSEKKASDSLKKYRGAIHREEIFPSLTRRTRERDRMLQQAHYQPINGDSQLTEPSTMITQLDGERERDNLSKCLKLAKEREQMEKELEHYTASRRVQAHEREQRRAKSASPLRKWTGVESQDPIWKPQDIQLRQKSRPSSLAQHVSDNRRGCYFGNTSSPMERHPSSSSSYIQWDISPVTSPTSLVPVQSLSEGNTPHSLYPNMRQQAIPNVEGSSATGISHSPATQYTSLSIFTPHRESSPSRSSLHGAQARYSESQLEEELPNRTLVEESWLAERKIEKESPPFRSKSPAHLSPQPSELHQVLEGADRDANSHYLDPRSQDVTDKEEEGIVQKDRLLSRNPSGCSTLPYDHKRGAKEKVIDDSLSILPYNEQEKEGIRARSRKSDKCVLTESPSRISPLTLLENEAESDQSNFSRMSESMKVKLASQPARMSPLQTSTILEYLSLPGFIEMSVDDPVEVTEPSESVEPNVELESGTMLRVEPDVVPKSWEKHSQDLSGTNGVVHDHGTQNVPMEKPKPEDISEPLPQLEARDRCVKSGTSDKSNKRFPPLKEKNKSSEPLLSQSSGSQREQFIQHGPAQTLINTAKSMAAIVSKCPDFISQQYQRPQIHSDSTNMISSRINQAPVPFMKKSVSIGPCRTLSGAGQPRPFLRKSISLGSRYEHSELPRPYFSETCYRDQFPNPDIRLKSYSLGRTPSHYYPISGPSWRGSVPYQPPHSYSLERHHIERSGMTPPYQTTFVPNPSRQMEPSLPSRRESDPRRQAAVFPDSSRWPLSYQETLRSVQHKYVPQDPPRPFGPNRSLARVDYMHPAEPRRCPPRPFLPRGYSWPSPHHPSFPLREHDFPRELDKGMGAVRGCAETERDGGRASYASQSSGRGSVGPYGHLRQSLSITPTLLSSPETTEESERHRADKDTRERRSKRRNTSVDESYEWDAVEYSMDHD---------------------------VLEAMKVERPHAAFGRGRGFRPERPRSTAGLQDLQSKRLYSVSPPLVSQPPQHRYSRSLSEARFNALRQEFQEYRRAQESCTQDPCIPHDPDSDSSSALL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6E7-1", "uniprot_id": "A0ACD6B6E7_DANRE", "id": "A0ACD6B6E7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MRLKNLPLLEVIVAV-LCLFNDTSA----AEEHVRAKKDSSAVLPCSLPAPQKDSSAS----QYVIEWVR----QGFDTPIFMQLG-VHPRVHPDYDGRVS------LFGGTSLQMSGLQLEDEGWYECRILPLDQTTEEAGSS-GSWTRLFVTAPPVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKDGAPIKP-QHKVKMVNG-SVSFHAVSREAAGQYQCYSSNSEGNATHVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPVSPSASAVLTVQHPAQVIQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKDGKPLDLGMYPGWTLASDGSIVIATVNDDAAGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNEYRQDVGTMLVIPCQMVGNP---APKVNWR-KIGAATRSLFT---LAGNGSLILHPLSKDHQGEWECSSSNRVATVSIKTMVLVLGTSPHAVSSVSVIPGTNQANVSWVAGFDGG--YTQTFTVWYKQVSAGRTEEKQEWLSFSDL-STENSLLVTNLLPATEYQFSVMAQNKIGTGPFSEIITVTTLD-----------------------ALPVVAKLEPPTNLSVNKSSEGFLLLWSAPHSKSPPIDSFVVQSRLEGGEWDNLKEDISPAESKIFLPGLCKDCKYELRLLSQHGDQLSMPSPSISVSTFGMNMRPASSRLLDFP-NHIMAGVMGGVGLLCLVLVLTLAIVCFISYKRSRRRRQNIKDLPPAMDK------NASVNIPD-----------------------------DTLKQRLLP---AHPLSTSSSASNHSSLDKFSHSDFHDLRQHHLPQANPPSHHSLPESHLQLSSLAPVSSVEFIHRGPDGRFVVHPGEG--DSNFSSQIKRNPNQNSHQASDGSRSFRIQKSQSLRSYMDEQRRPPFVLSVDLPPFGSNIPSSSRTRAMVKHLSLNGHYMPILEK-EIMDVPDQTSLSSDCSDSYLYAHSES------------TLGQKSPKR--------------DTNHSTASTLVLQMEHEREQGNLSRCLTLAREREELERELRKYTVDLNSSSHEQTD---------------DEYGNLWKTQEASTPQVKYQTMRQSILSEN---------TGMFKRR---AASCIPWEERHKISSANLLPLHKSYEKDIKYRQN-----QGYNSVQRS-------------------------------------RYQRS-------------------RSLDREE---------------------------HRKSHTWDQRR-------------------------SKTPVESSR----YCVMDELIYKLENPQTCEGPRAR--------MTSSRS---------------QHYFDPCIYPSPGDQQWRTVQRSNREIHPVGDYS------EMSVDGP---------------------------------DFESQHANSRSTVRSEHSYETLDYDRPR-------LSELEM-DRLVKPGHVS------------SRKDKKLNNWSS-------------------------------------------KTESPMNVSERMPQR-----------------------------TNSIGSKIRDQHQSTHSLDSKLYKDQFLTPDAWIDSLTLPQDCTMSPLVSRP---NSVANKPKSSPNLQDH-------------SFVPSGS---QSHVPQRRASKS-------PNGFTNDQHSQRNLMSERNAHTALPPG-----GSSLPRAYYPSLST---------LPS--ERRNQSHQAGREEEDMDGQDMDVEINIYRKGSET--EGSYRSYGSQSSGRGSMDAP-NSRQ-FSLSPPLTSSPETTEDSDRDEAALLDPEQNGRR--DSVDESYEWEPAYVPMRP----------------------------VVSMNKTGLQKEFKGSQRKQSSITKDDDSSNLDQKQKGLYPAAGLKGSVPLFEVPCVPPSQC-----QQESLLTRDIQKSFTS----FSDPEPD--TVLF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZB51-1", "uniprot_id": "TUTLB_RAT", "id": "D3ZB51-1", "name": "Protein turtle homolog B", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVISTRGLVAQVAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQP-----PPYVVEWFK----FGVPIPIFIKFGYYPPHVDPEYAGRAS------LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHN--GSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLSA-SGKYQVSDG-SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDP---FPVITWR-KVGKPSRSKHN---ALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGG--YEQTFSVWM----KRAQFGPHDWLSLSVP-LGPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVT-------------------TPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVG-ERWEMLDDAIPGTDGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSST--DIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCR------KSLESPL-----------------------------SSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEATTP-IELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDP-LVPTSVAALKP-QLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGG-------------------------------------------------------------------RLQATGQAR-PPAPRPFQHGQYYGYLSSSSPGEVEPPPFYMPEVGSPLSSVMSS----------------PPLHTEGPFGHPTIPEENGE------NASNS--------TLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFP--HQLHPCD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAESLQPKPCLPRGLPPAPLQVPAAYPGMLSLEAP-------------------------------------------KGWVGKSPGRGPIPAPPATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFG--------------------------------------------------------------------------------------------LDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQA--------------EMSEITLQPPAAVSFSRK-------------------------------------------------------------------------------------------------------------STPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDNLDVFGQTPSPRRMGEEPLRPE-PP----------------------------------------------------------TTLPTSG--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZ19-1", "uniprot_id": "TUTLB_MOUSE", "id": "E9PZ19-1", "name": "Protein turtle homolog B", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVISTRGLVAQGAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQP-----PPYVVEWFK----FGVPIPIFIKFGYYPPHVDPEYAGRAS------LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHN--GSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGA-SAKYQVSDG-SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDP---FPVITWR-KVGKPSRSKHN---ALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGG--YEQTFSVWM----KRAQFGPHDWLSLSVP-PGPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVT-------------------TPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVG-ERWEMLDDAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSST--DIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCR------KSLESPL-----------------------------SSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEATTP-IELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDP-LVPTSVAALKP-QLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGG-------------------------------------------------------------------RLQATGQAR-PPAPRPFQHGQYYGYLSSSSPGEVEPPPFYMPEVGSPLSSVMSS----------------PPLHTEGPFGHPTIPEENGE------NASNS--------TLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFP--HQLHPCD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAESLQPKACLPRGLPPAPLQVPAAYPGMLSLEAP-------------------------------------------KGWVGKSPGRGPIPAPPATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFG--------------------------------------------------------------------------------------------LDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQA--------------EMSEITLQPPAAVSFSRK-------------------------------------------------------------------------------------------------------------STPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDTLDVFGQTPSPRRMGEEPLRPE-PP----------------------------------------------------------TTLPTSG--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPX0-1", "uniprot_id": "TUTLB_HUMAN", "id": "Q9UPX0-1", "name": "Protein turtle homolog B", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATFIASVIGTRGLAAEGAHGLREEPEFVTARAGESVVLRCDVIHPVTGQP-----PPYVVEWFK----FGVPIPIFIKFGYYPPHVDPEYAGRAS------LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHN--GSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGA-SGKYQVSDG-SLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDP---FPVITWR-KVGKPSRSKHS---ALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVQVSMTTANVSWEPGYDGG--YEQTFSVWM----KRAQFGPHDWLSLPVP-PGPSWLLVDTLEPETAYQFSVLAQNKLGTSAFSEVVTVNTLAFPIT-------------------TPEPLVLVTPPRCLIANRTQQGVLLSWLPPANHSFPIDRYIMEFRVA-ERWELLDDGIPGTEGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSST--DIFPQPDLTEDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCR------KSLESPL-----------------------------SSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSKKYSVAKAEAEAEATTP-IELISRGPDGRFVMDPAEMEPSLKSRRIEGFPFAEETDMYPEFRQSDEENEDP-LVPTSVAALKS-QLTPLSSSQESYLPPPAYSPRFQPRGLEGPGGLEG-------------------------------------------------------------------RLQATGQAR-PPAPRPFHHGQYYGYLSSSSPGEVEPPPFYVPEVGSPLSSVMSS----------------PPLPTEGPFGHPTIPEENGE------NASNS--------TLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFP--HQLPPCD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPESLQPKAGLPRGLPPTSLQVPAAYPGILSLEAP-------------------------------------------KGWAGKSPGRGPVPAPPAAKWQDRPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGAHGGPSTFG--------------------------------------------------------------------------------------------LDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQA--------------EMSEITLQPPAAVSFSRK-------------------------------------------------------------------------------------------------------------STP-STGSPSQSSRSGSPSYRPAMGFTTLATGYPSPPPGPAPAGPGDSLDVFGQTPSPRRTGEELLRPETPP----------------------------------------------------------PTLPTSGKLQRDRPAPATSPPERALSKL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NYK6-1", "uniprot_id": "A0A8M9NYK6_DANRE", "id": "A0A8M9NYK6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQ-----TPYVVEWFK----FGVPIPFFINFRFYPPHVDPEYAGRAS------LHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHN--GSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTS-TRKYTVSDG-SLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPE--IPTIQWR-KVGKPSRSKHN---LLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGG--FEQTFSVWYGPVKVKNDVGTHDWLSIPVP-GSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPIS-------------------TPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLG-EKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSST--DPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTR------KSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSK--HEAEVTTP-IELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRP-QISPVSSSQESYMQPPAYSPRFQ-RPMEGMSISEGS------------------------------------------------------------------RLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVEL-HPPFYMPDV-SPRSSAMSSS---------------PSYPPEGPFRHPTIPEEREELRIHQYGASGH--------ALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLPEPPPYPSHSRTVS-TTSQLPS-SSAFLQLEAP-------------------------------------------RTHLSRSPGRFPPQGPSAKHIT---MQQAQTLGQLRHTAHGMGVPVLPYSGATT--RMGSPSTLHS-----------------------------------------------------------------------------------------ESSDGWRSEAQP--WMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSR-----------SQEMPESARHP-ASVSFSRRSLS----------------------------------------------------------------------------------------------------------SSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSP----PAESSDAFGQMPSQRRTDEEMLPSEPSP---------------GEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TAW7-1", "uniprot_id": "A0AB32TAW7_DANRE", "id": "A0AB32TAW7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTSRAGETVILGCDVVHPLNGQ-------PYVVEWFK----FGVPIPFFINFRFYPPHVDPEYAGRAS------LHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHN--GSWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGNPVQD-STKYKVSDG-SLTLVSISREDRGAYTCRAYSEQGEAVHTTRLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPEDAGKYTCSPSNSLGRPPSASAYLTVHYPARVINMPPVIYVAIGLPGYIRCPVDANPPVTSVKWKKDGLPLRIEKYPGWSQMEDGSIRVSEVTEDSLGTYTCVPYNSLGTMGPSPPAPLVLKDPPKFLVVPGGEYRQEAGRELVIPCEAEGDP---FPNITWRKKVGKPSRSKHN---VLPRGSLQFKSLSKEDHGEWECVASNVATSITASTHLLVIGTSPHAPAKVHVTVSTTSANVSWDSSYDGG--FEQTFSVWYGHVVKREQLGPHDWLSMPVP-SGQHWLLVQGLEPETAYQFSVLAQNKLGTGPFSEVVTVNTLVFPIS-------------------TPEPLVLLTPPRCLTANRTQQGVLLTWIPPANHTSPIDHYIMDFRLG-ERWDVLDDAIPAGETEILARDLIQEAWYEFRVMAVMEDLVSEPSNVVGVSST--DYFPPPEVPDEGLARPVVAGIVATICFLAAAILFSTLAACFVNKQRRRKLKRRRDPPLSITHCR------KSVETPS-----------------------------SSGKISPESIRSIGPPSESSE--DGLRAKKFPQSPAKEELSLYKKTKRAIISKKYSVSK--HEAEATTP-IELISRGPDGRFVMDPTDMETPVKARRIEGFPFVEESDLYPEFRQSDEENDDPGPMPPVMATLRPHQISPISSSQESYLQPPAYSPRFQ-RPMEGMTIMETS------------------------------------------------------------------RLQATGQIRGAPHFRAFTHGQFYSYLGSPGEPEP-PPPFYMPDT-SPLSSVMSS----------------PPYHLEGPFGHPTIPEEIGEGEIQHYAVSGY--------TLPLAH-PSTSRSPDIWQRPDFTFATIEGPHFIFPPPHPLHLHP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPPLPPPLVLPPSALQPSTLQVSP-YPGILQLEAP-------------------------------------------KSRPGKSPSKVKPQGLPAKRLP---MQEAQSLGQLRHTSHGMGVPVLPYPDPVS--HMVGPSSFG-------------------------------------------------------------------------------------------SLDTRWYELTP--RLSPRQPRRMEP--SMVVLQPSRLSPLTQSPISSHEGSPEIVVRPRPRPSMIQPPI-----------PPEMSEITLQPPSSASFSRR-------------------------------------------------------------------------------------------------------------SSPSSSPAQGQGSRRASPSYRSHMAFATSAASYPSQSPSP----PVESSNIFGQMPTQRRTEEEILPSEPSPPQLSASGYIHYVAILRKRRGAPSGSAGSERIEALRYQRVKKAKKVGIN-NNNSKARRKTGVPPSQTQQPHTSQVLQPEEALYLRKKK--KKLTRQDPYARFSALLYRRPTREDQKAILASMDTADPDHATLL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q967D7-2", "uniprot_id": "TUTL_DROME", "id": "Q967D7-2", "name": "Protein turtle", "aln": "MGVCADLGSHRWCRALSTQHNTEKSKEQQQQSQPLEIPEQRASKCRGDIDRTTTTTIPASKTLTASPAKTAAFTVKTTRRRRSRRRAEGSSICVPIRRGQGSTPTPTIQVLQFVLVSLLALLAKNAQAHN-IPEDAVHITAILGEGVIFNCHVEFPNDHP------VPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKN--GTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFR------EAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKAATQPPDSFFQLMPDEAGPKPGPPRNVSVTEVSNGFLITWQSPLERAHIVKFYTIKYRTDAQWKTLNRGQIRPEETQYLVKNLVGGRTYYFRVLANSEKSYESSDEVK---------FPVPAR---VKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEFNMVACRITDAR------NIAANN--------------------------HHLHNRSTGSISSGQVPLKKYKQTRISSLTAILIAILHWIWPPDRCTNCHSIYSSPNLEDGDEDDGGGGRRRSVSRIQRSLDGRFVLDVEGVS--KLGYSQQTLESGNVDVVDGGLFERRNSNVSQKSSSDDGGFLSRRNFITARASWRRPLVASSSQLSLQSAADSARGFLQG--------------------------------------------------------------------------LLKIGAKQSAVPPNSQSYFDEAVSGARYQNVLRPYTSSNNLYGNADRS---------------RPLHINTISGSLSQQQQLYTPSRISRIFS----------SSPQQLQPHHQQLLLSSGGSGAYPTHFSDLSTVYPPNSAERSSHN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSSRYRYYSQELPSLRTIQEETRRQQQQKQHP----------------------------------------------LEDHFVPLQLPSPPSWRSYYQSQASYRPRTRWYPRHHSRLFS-----------------------------------------------------------------------------------------------------------------NRQQQHEMLSPLPQLNLNLRNSMNPGGLEASPESRSSSSGFGSKNTSNHPGSTSEWRLLPPYRAPP--------------SPPKHSGYFGGQQAQGQTP------------------------------------------------------------------------------------------------------------HGSYSYPRATTPPYTMAHWLEMISRLNAATDSNLPKAPCPVDVGSVDGHYEFDPATPTPSASSMLREDLNLH-----------------------------------------------IDTHPYHHHTLGPLSGSLLHSHAPYGGGARKQRSLPAHLPRYDNVEVRLQAMREEFYAYRKRQAMQQMESVC--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . . : * : * :*::* : * *: : ::. * **. :** : : .*:**:**::. *:: *:* * : :** : *. : . .: : * * *.* * : * . : : . : : * * * . :*. * ::: : * . *: .* : . .:.. : *.*:* * *:* * : : *: *: : **:* : *:*:* * * :*.: . :*** *:* :**:* * :. : * : * : :.* : * ** * . :**: . .:: * * *..** ** * * :::: ** * * * :..* : : * * : * : * ..: : * :: * ::* * .: : * : : **.**. .: .:.* ..:.** : * :::* ::* ::. : : * . : *:*.*:.:* :* . :*::: . ** : . . *.*: * .* . : : :. : : . : .* * :* :: . . .. * . : **::. : :: .::.: . . :: : .:. . . . . :. * *. ****:: . : . . . . . : . . : * : . . . .. . . . . ", "identical_positions": 133, "similar_positions": 235, "identity": "5.95%" }, { "cls_id": "homologset.agr.FB:FBgn0010488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62448-1", "uniprot_id": "IF4G2_MOUSE", "id": "Q62448-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MESAIAEGGASRFSASSGGG--GSR---GAPQHYPKTAG---------------------------------NSEFLGKTPGQNAQKWIPARSTRR---------------------------------------------------------------------------------------DDNSAANNSANEK-------------------------------------------------------------------------------------------------------------------------------------------------------ERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQG-RSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQ-----SQFGEMGGKFMKS-QGLSQLYHNQSQGLLSQLQGQ-----------------SKDMPPRFS----KKGQLNADEISLRPAQSFLMN--KNQVPKLQPQI-TMIPPSAQPPRTQTPPLGQT-----PQLGLKTNPPLIQEKPAKTS---------------------------------------------------------------------------KKPPPSKEELLKLTEAVVTDYLNSGNAN---------------------------------------------DAVSGVREMRAPKHFLPEMLSKVIILSLDRS-DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIIS---ELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDN--ISPKLHVD-----------KGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDIT---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNC4-1", "uniprot_id": "A0ABZ3NNC4_RAT", "id": "A0ABZ3NNC4-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------VESAIAEGGASRFSASSGGG--GSR---GAPQHYPKTAG---------------------------------NSEFLGKTPGQNAQKWIPARSTRR---------------------------------------------------------------------------------------DDNSAANNSANEK-------------------------------------------------------------------------------------------------------------------------------------------------------ERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQG-RNDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQ-----SQFGEMGGKFMKS-QGLSQLYHNQSQGLLSQLQGQ-----------------SKDMPPRFS----KKGQLNADEISLRPAQSFLMN--KNQVPKLQPQI-TMIPPSAQPPRTQTPPLGQT-----PQLGLKTNPPLIQEKPAKTS---------------------------------------------------------------------------KKPPPSKEELLKLTEAVVTEYLNSGNAN---------------------------------------------DAVSGVREMRAPKHFLPEMLSKVIILSLDRS-DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIIS---ELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDN--ISPKLHVD-----------KGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDIT---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78344-1", "uniprot_id": "IF4G2_HUMAN", "id": "P78344-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MESAIAEGGASRFSASSGGG--GSR---GAPQHYPKTAG---------------------------------NSEFLGKTPGQNAQKWIPARSTRR---------------------------------------------------------------------------------------DDNSAANNSANEK-------------------------------------------------------------------------------------------------------------------------------------------------------ERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQ-----SQFGEMGGKFMKS-QGLSQLYHNQSQGLLSQLQGQ-----------------SKDMPPRFS----KKGQLNADEISLRPAQSFLMN--KNQVPKLQPQI-TMIPPSAQPPRTQTPPLGQT-----PQLGLKTNPPLIQEKPAKTS---------------------------------------------------------------------------KKPPPSKEELLKLTETVVTEYLNSGNAN---------------------------------------------EAVNGVREMRAPKHFLPEMLSKVIILSLDRS-DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIIS---ELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDN--ISPKLHVD-----------KGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDIT---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4J3-1", "uniprot_id": "A0A8M1N4J3_DANRE", "id": "A0A8M1N4J3-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MESVIAEGGASRFSASSGGG--GGR---GASQHYPKTVG---------------------------------NSEYLGKTPGPSVQRWVPSRSTRR---------------------------------------------------------------------------------------DVN-----SSTEK-------------------------------------------------------------------------------------------------------------------------------------------------------EHHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVDSKLVLKGIILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPTPEIQSSQKQSTTFRRLLITKLQDEFENRTKNVDLYDKQDNPLTSEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEK--KKR--VQLKDMGEDLECLCQIMRTVGPRLDHEKAKSLMDQYFGRMQSLMNNKDLPARIRFLLQDTVELRENNWVPRKAFIDNGPKTINQIRQDAVKDLGVFIP-PMNQGMRMDFFLEGPFMPNRMKLDRETLGGLADMFGQMPGS--GIGTGPGVIQDRFSPTLGRHRTNPLFN---GHMASQPQ-----SQFDLGMKPFMKSNQGQNQHFHNQNQNHLNQQQAQ-----------------SKDMPPRF-----KKGQMNADEISLRPAQSFLLN--KNQVPKLQPQIPTMIPPSAQPPRTQTPPLGQP-----PQLGLKTNPPLIQEKPQKTT---------------------------------------------------------------------------KKPPPAREELLKMTENIVTEYLNNRNME---------------------------------------------VAVSGVREMKAPKHFLPEMLSKIILCSLERT-DEDREQASTLINTLRTEGFITGEHFMQALLNVLDQCPKIEVDIPLVKSYLAQFAARAVIA---ELVSVAELAHPLENGNHFPLFLLCLQQASKLKDREWLTDLFQQSKVNMQKMLPEIDQNKDRMLEVLEGKGLSFLFPLLKLEKELLKQIKADPSPQTIYKWIKDN--ISPKLHID-----------KGFINILVTSFLQYIFAELGVP-ECDEQLSFPSKEQLDQEKQLLHSFKPVMQKFLHEHTNLQVSALYALQVHCNANAFPKGMLLRYFVHFYDMEIIEEEAFLAWKEDIS---QEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z968-1", "uniprot_id": "A1Z968_DROME", "id": "A1Z968-1", "name": "Eukaryotic translation initiation factor 4 gamma 2", "aln": "MPLSTYDAAPLLHSYDDSPQRWSGVTNGHQAGVIIDQFRGGKAIIIEGGTSTGDTKSIGGGSDLRLVITANPSEIERNYEQPTNRGGGGGGGVIGVSCGGQTPPTPSVGKTLLNTSPNLLPITTATDTFNNLKNLVKIDKGSSPSSGSNSLGGNYRKGGSNGSGYKSAGGNGGSPAISGNSEGGRNGSRSSGGPTGHFSTGYSKNSVKIRQHDSEVSPRPRRSYQGDSSSSRYYPKNSDILGQGLGGNSDSYNGSSSSGRYQQQDQQGGSHRGSRSNYHSNSDGSYNRSINSNSVGGGGSGAVGSGSGGSNYRSARNYENGNGSNGTQPRYGSGNGNGNSSNSNSSSGYNGSAASSTNSKSSYGASRGGNDGGVSSGYSSNYRDNYEDSPSHQRYNNTNSLERNGGGGSGAGASGGPRSYGRSDADRYGGTPSSRTPNLRNGSASAQISGSTSNSSNISLNSGSASAAGGGTPHSQQQQERSQAGKASTPPPITGRWIPPSLRPQHGLTQSEKNDAVFRRVRGILNKLTPEKFQELSDELLKLDLNSIAILKGVILLIFDKALDEPKYSSMYAQLCKRLSEEAPSFD-------KEPSNSSTFLRLLIAVCRDKFNNRLKRDENDNRPPPENEADEEERRHLAKQRMLGNVKFIGELNKLDMLSKNVLHQCIMELFDK--KKKRTAGTQEMCEDMECLAQLLKTCGKNLDSEQGKELMNQYFEKLERRSKSSEYPPRIRFMLKDVIELRQNNWVPRKLGTTEGPVPIKQIRSDDDSIIRTPFP-NRNRDMRNNDRDSDSWMN-RFHLNIQP-GGYNDMFSGLSVT--GASP---IVSPFATSNRDRDRDNRQYNNRGDRNRDRDQGGSGGANYGNRYNKHNQNGGGSGGGSSNNRDRDDSRRNNDRDRDRNDGQYGGNQLLGSKELAPRFKRNLITTNQDAVENLQMRPAANSLLFRAASQNQKFPATLPMSTPPNSSGSNNQGSSQGQLSNSHYPMLGTPTSHLINPTRPSSTPSAEYADNRTLLGVQQERGLKATSSSPNFSSGAEKLDLDGQAGRKGSHDGKDQGKNGSVERPSTPAGGIGSAKQQKKDKGPNKEELSKKASQYFKDRFYYDEEEDAEVTEIEIKDIDETKTEEADAAPVEVSEVKEDAAIPVTTPDRFTKLVDGFLELKLPEKALKDVCINLLMEVLDRVNDVFLERAVRLLQTLRKQSNIKPNIVVEIFKQVVNKMNEREALNPRIVSLVASLLAKTICEP--ALLKLSDIANFTDNGQHYPLFLLVLQQLVKVIGKDALEEKFRASKVDLMNSLPEADRNKERLAGILEDRKLSFLYPLLKVQAEMLKQLQSDPNPNNFYKWIKAN--VDNKYYKD-----------PGFIQALMTVVVKYVTKETTLA-DNLDPKEHPEKSVTQKEQQLLENYSQMLQTFLGQNE-LQLMALYALQTFCYNENFPKGMLCRWFKYLYESEIIEEEAFVLWKEEIS---DKYPGKGSALFQVNAWLTWLQEAESEDDED---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39936-1", "uniprot_id": "IF4F2_YEAST", "id": "P39936-1", "name": "Eukaryotic initiation factor 4F subunit p130", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MTDQRGPPPPHPQQANGYKKFPPHDNQYSGANNSQPNNHYNENLYSAREPHN-NKQYQSKNG------------------------------------KYGTNKYNNRNNSQGNAQYYN-----------------------------------------------------------------------------------NRFNNGYRLNNNDYNPAMLPG-------------------------------------------------------------------------------------------------------------------------------------------------MQWPANYYAPQMYYIPQQMVPVASPPYTHQPLNTNPEPPSTPKTTKIEITTKTGERLNLKKFHEEKKASKGEEKNDGVEQKSKSGTPFEKEATPVLPANEAVKDTLTETSNEKSTSEAENTKRLFLEQVRLRKAAMERKKNGLIS--------------ETEKKQETSNHDNTDTTKPNS--VIESEPIKEAPKPTG----------EANEVVIDGKSGASVKTPQH-----VTGSVTKSVTFNEPEN---ESSSQDVDELVKDD------DTTEISDTTGGKTVNKSDDETINSVITTEENT--------VKETEPSTSDIEMPTVSQLLETLGKAQPISDIYEFAYPENVERPD-----IKYKKPSVKYTYGPTFLLQFKDKLKFRPDPAWVEAVSS--------------KIVIPPHIAR------NKPKDSGRFGG------DFRSPSMRGMDHTSSSRVSSKRRSKRMGDDRRSNR--GYTSRKDREK----AAEKAE-----------------------------------------------------------------------------EQAPKEEIAPLVPSANRWIPKSRVKKTEKKLAP-----------------------------------------DGKTELFDKEEVERKMKSLLNKLTLEMFDSISSEILDIAN--QSKWEDDGETLKIVIEQIFHKACDEPHWSSMYAQLCGKVVKDLDPNIKDKENEGKNGPKLVLHYLVARCHEEFEKGWADKLPAGEDGNPLEPEMMSDEYYIAAAAKRRGLGLVRFIGYLYCLNLLTGKMMFECFRRLMKDLNNDPSEETLESVIELLNTVGEQFEHDKFVTPQATLEGSVLLDNLFMLLQHIIDGGTISNRIKFKLIDVKELREIKHWNSAKKDAGPKTIQQIHQEEEQLRQKKNSQRSNSRFNNHNQSNSNRYSSNRRNMQNTQRDSFASTKTGSFRNNQRNARKVEEVSQAP--RANMFDALMNNDGDSD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39935-1", "uniprot_id": "IF4F1_YEAST", "id": "P39935-1", "name": "Eukaryotic initiation factor 4F subunit p150", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTNYNNGSNYTQKKPYNSNRPHQQRGG------------------------------------KFGPNRYNNRGNYNGGGSFR-----------------------------------------------------------------------------------------GGHMGANSSN-------------------------------------------------------------------------------------------------------------------------------------------------------VPWTGYYNNYPVYYQPQQMAAAGS-----APANPIPVEEKSPVPTKIEITTKSGEHLDLKEQHKAKLQSQ-ERSTVSPQPESKLKETSDSTSTSTPTPTPSTND--SKASSEENISEAEKTRRNFIEQVKLRKAALEKKRKEQLEGSSGNNNIPMKTTPENVEEKGSDKPEVTEKTKPAEEKSAEPEVKQETPAEEGEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEAEVEAEAGDAGTKIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPD-----IKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTAS--------------KIVIPPGMGRG-----NRSRDSGRFGNNSSRGHDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNR--SYTSRRDRERGSYRNEEKRE-----------------------------------------------------------------------------DDKPKEEVAPLVPSANRWVPKFKSKKTEKKLAP-----------------------------------------DGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIAN--ISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGTPLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQTAKISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQLKNNSRSNSRRTNNS---SNRHS-FRRDAPPASKDSFITTRTYSQRNSQRAPPPKEEPAAPTSTATNMFSALMGESDDEE-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . : . . . * . . . . : :::.. : : * *: :. . .. : * .. :* .* : . . : *: : * . : : . .: . . : * : * . . . : ... .: .: . .. . . :. . :. . : :: . . : . :.* : : :. : . : ... . .: . . : . * :. . . : . : :: : .: :: : :: . * . . :. . : : :. :: . . : .: . : : * : :: . * : .: . . . *: * * ::: .::*:: .*. :.: . :: :. : * ::: *. . : : . . . .: :. . : :. : . * : ..::* : :. . . : : * :. : ", "identical_positions": 25, "similar_positions": 197, "identity": "1.64%" }, { "cls_id": "homologset.agr.FB:FBgn0010497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3I8-1", "uniprot_id": "D4A3I8_RAT", "id": "D4A3I8-1", "name": "", "aln": "---------------------MDEKPTTRKGSGFCSLRYALALVMHFSNFTMIT-QRVSLSIAIIAMVNSTQHQDPANASAEGPVMNLLSNRSRGIKDFSTRAAVYQWS----TETQGIIFSSISYGIILTLIPSGYLAG---------IFGAKQILGAGLLISSLLTLFTPLAADFG-----VILVIVIRTVQGMAQGMSWTGQFTIWAKWAP----PLERSKLTSIAGSGAAFGSFIILCVGGLISQALG--WPFIFYIFGSIGCVCCVLWFTMIYDDPMH----------HPCISVKEKEYITS------SVAQQSSSPRRS-IPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTILGGQMADFLLSRNL------LSLITVRKLFSSLGLLLP--------SLCAVALPFVTSSYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQVG--------HVIEHLQVAGF-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00624-1", "uniprot_id": "NPT3_HUMAN", "id": "O00624-1", "name": "Sodium-dependent phosphate transport protein 3", "aln": "---------------------MDGKPATRKGPDFCSLRYGLALIMHFSNFTMIT-QRVSLSIAIIAMVNTTQQQGLSNASTEGPVADAFNNSSISIKEFDTKASVYQWS----PETQGIIFSSINYGIILTLIPSGYLAG---------IFGAKKMLGAGLLISSLLTLFTPLAADFG-----VILVIMVRTVQGMAQGMAWTGQFTIWAKWAP----PLERSKLTTIAGSGSAFGSFIILCVGGLISQALS--WPFIFYIFGSTGCVCCLLWFTVIYDDPMH----------HPCISVREKEHILS------SLAQQPSSPGRA-VPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFIAAASCTILGGQLADFLLSRNL------LRLITVRKLFSSLGLLLP--------SICAVALPFVASSYVITIILLILIPGTSNLCDSGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLISQVG--------PVY---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JXU5-1", "uniprot_id": "A0A0G2JXU5_RAT", "id": "A0A0G2JXU5-1", "name": "", "aln": "MSTGADLKAREGGIPNDSNLNMTQEQSFKKG--CCSLRHGLAFILHLCNFSVYT-QQMNLSIAITAMVNTTAASSHANASIERPTTDSQDFWNETLQESK--APVYDWT----PEIQGILLSSLNYGSFLAPIPTGYVAG---------VFGAKYVVGLGLLVSSVLTLFIPLAAEAG-----VALLIVLRVIQGMSQVMVLTGQYSMWAKWAP----PLERSQLITIAASGSMLGTFLVLIAGGLLCQALG--WPYIFYIFGGIGCACCLLWFPLVYDDPQN----------HPFISTGEKRYIMC------SLAQEDCSLGWS-LPIKAMVKSLPLWAIVVSYFCEYWLLFTIMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIILGGLLADFLLSRNI------LRLVTIRKLFTALGVLVS--------SGILVPLPWVSSSLSTTMAFLVLSSVFASLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFGWRNVFLLAAAIDVVGLLFYLIF----GRAEVQDWAKEPTFTHL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2C5-1", "uniprot_id": "S17A4_HUMAN", "id": "Q9Y2C5-1", "name": "Probable small intestine urate exporter", "aln": "MSTGPDVKATVGDISSDGNLNVAQEECSRKG--FCSVRHGLALILQLCNFSIYT-QQMNLSIAIPAMVNNTAPPSQPNASTERPSTDSQGYWNETLKEFKAMAPAYDWS----PEIQGIILSSLNYGSFLAPIPSGYVAG---------IFGAKYVVGAGLFISSFLTLFIPLAANAG-----VALLIVLRIVQGIAQVMVLTGQYSIWVKWAP----PLERSQLTTIAGSGSMLGSFIVLLAGGLLCQTIG--WPYVFYIFGGIGCACCPLWFPLIYDDPVN----------HPFISAGEKRYIVC------SLAQQDCSPGWS-LPIRAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGCICIILGGLLADFLLSRKI------LRLITIRKLFTAIGVLFP--------SVILVSLPWVRSSHSMTMTFLVLSSAISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFISQDSEFGWRNVFLLSAAVNISGLVFYLIF----GRADVQDWAKEQTFTHL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PTR8-1", "uniprot_id": "E9PTR8_RAT", "id": "E9PTR8-1", "name": "", "aln": "MATVVELSPTSEQCEFVLGLPVNKKTPPRKVPSLCSMRYSIAFIAHICNFTLIA-QNSIISITMVAMVNNTDQPSHLNSSTEWFPDGLNGDQHEASKHLSIKAPVYNWS----PQTQGIIFSSVQYGMMLMQGPGGYLAG---------KLGTKKVVGIALLGSSLLTLCIPLAANLG-----LAFLLATRAVQGLTQGAGYGGQFALWQKWAP----PNERSRLCSIAMSGMILGIFAVLLVGGIISEALG--WPFVFYIFGSIGVVCCLLWLILVYDDPVS----------HPWISSPEKEYILS------SLDQQFNSEEQP-LPIKAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAWVIGILGGLLADFLLSKN-------FRLITVRKIITILGNTPP--------AALVVALPYVQSSYIATTTFLTLSCGLSPLCQSGVYINALDIAPRYASLLMGTSRGLAHSSAVMVPIVAGFFLNQDSEFGWRNFFFVLFAINLFGLIIYLVF----AKADIQEWARERKLTRL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62795-1", "uniprot_id": "NPT1_RAT", "id": "Q62795-1", "name": "Sodium-dependent phosphate transport protein 1", "aln": "---------------------MENRCLPKKVPGFCSFRYGLAILLHFCNIVIMA-QRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKN-------------PVHSWS----LDIQGLVLSSVFLGMVVIQVPVGYLSG---------AYPMEKIIGSSLFLSSVLSLLIPPAAQVG-----AALVIVCRVLQGIAQGAVSTGQHGIWVKWAP----PLERGRLTSMTLSGFVMGPFIALLVSGFICDLLG--WPMVFYIFGIVGCVLSLFWFILLFDDPNN----------HPYMSSSEKDYITS------SLMQQVHSGRQS-LPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKI------FSVVAVRKLFTTLGIFCP--------VIFVVCLLYLSYNFYSTVIFLTLANSTLSFSFCGQLINALDIAPRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEYAWHKNFFLMAGINVTCLAFYLLF----AKGDIQDWAKETKTTRL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14916-1", "uniprot_id": "NPT1_HUMAN", "id": "Q14916-1", "name": "Sodium-dependent phosphate transport protein 1", "aln": "-------------------MQMDNRLPPKKVPGFCSFRYGLSFLVHCCNVIITA-QRACLNLTMVVMVNSTDPHGLPNTSTKKLLDNIKN-------------PMYNWS----PDIQGIILSSTSYGVIIIQVPVGYFSG---------IYSTKKMIGFALCLSSVLSLLIPPAAGIG-----VAWVVVCRAVQGAAQGIVATAQFEIYVKWAP----PLERGRLTSMSTSGFLLGPFIVLLVTGVICESLG--WPMVFYIFGACGCAVCLLWFVLFYDDPKD----------HPCISISEKEYITS------SLVQQVSSSRQS-LPIKAILKSLPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLSSLPYLFAWICGNLAGQLSDFFLTRNI------LSVIAVRKLFTAAGFLLP--------AIFGVCLPYLSSTFYSIVIFLILAGATGSFCLGGVFINGLDIAPRYFGFIKACSTLTGMIGGLIASTLTGLILKQDPESAWFKTFILMAAINVTGLIFYLIV----ATAEIQDWAKEKQHTRL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKC9-1", "uniprot_id": "DMGLU_DROME", "id": "Q9VKC9-1", "name": "Dietary and metabolic glutamate transporter", "aln": "------------------MTQQPQWGISLSRYFVIPQRVILAIMGFLAILNAYT-MRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEG---------TSVGGDFEWS----EELQGLILSSFYIGYIVTHIPGGLLAE---------KFGGKWTLGLGILSTAVFTMLTPLAINKGD----SDWLIVTRVLMGLGEGTTFPALSVLLAAWVP----ANERGKLGALVLGGGQVGTIMGNLLSGVFIDAYG--WEFVFYFFGGLGVVWFAIFMFLCYSDPTS----------HPFIKPSEREYLVK------EIGTISRNEDLPPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMIRRGV------LSTTNTRKVMTGLAAFGP--------AIFMVGASYAGCDRVLVVVLFTICMGLMGAYYAGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVIYCIW----ASGEVQPFNNAPIQPRSVDFEAQERKVGGEKTSGLEQSS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53322-1", "uniprot_id": "TNA1_YEAST", "id": "P53322-1", "name": "High-affinity nicotinic acid transporter", "aln": "MSNKFTMESPKHLVDDVLFISPTNDGSEEKPTEVTFQEDEGHDASLHNRSHDKK-SELATEREIMATTTDDDGIPSPSHPMEKRVLRKMDIYLIPLMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVLF--DPIGTNLLKIMGPPLMMSICLTCFGAISLGTAW-VKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYGCSKISGSLKD--WQYIYIVEGCISLGFVPFYAFGLSKNLED----------SWFFNKEEKEYISERYK---TMNTFDPDEKFEWFQVWQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGFTNVR-AQLMTVPIYFLTAIVFFICAVWSDRIKLRSP------FILGACLTTSIGIAIVLGS--QVHGVRYFGVYILCMGIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQIFLYKRENDKKKAIIDRC----NELGEPIPYDERLSDKNPEFKYMY---------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07904-1", "uniprot_id": "THI73_YEAST", "id": "Q07904-1", "name": "Thiamine pathway transporter THI73", "aln": "-----------MKNMSQRSMDVEKKAANADSCSVSTSSINVDDADVALRFLKQNGLDESSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLN--YAASMGIKDHLKGNEFSNLGTIFSAAYIFM--EPVVTYLIQKFPISKILGTFITVWGIVLACHAA-CKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLISFGFLHYHGTAFTS-WQIMFLVVGLVTVAFGVLTFLYLPDNVTN----------AWFLNKEEKIQVVEHIR---ANQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYETALLQLPIGAITAMIILITTQMLSRWGHITL------ITTSMYIPAIIGCIVLISLPLSHKIGNLFSLYLLYSG-SCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAKIALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQ----ERKKYQFLDLTDIENRNFRYIY-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P15365-1", "uniprot_id": "DAL5_YEAST", "id": "P15365-1", "name": "Allantoate permease", "aln": "--------MSADASTNSNASLDEKNLNITSEAEIKNEDVTAEPVLSTVLSPNGKIVYISDKVDEAMKLAEEAKEIEVTPEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVITGVITIFIGILIFLWIPDDPSK----------ARFLSKREKLMVVQRIR---SNQQGFGNHEIKKYQIIEALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFGILAVYAANKKIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYISPVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKVAMVVCYAVMIVLLSILLIVNLRENKRRDKIAAERGFPEETENLEFSDLTDFENPNFRYTL-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40445-1", "uniprot_id": "YIQ6_YEAST", "id": "P40445-1", "name": "Uncharacterized transporter YIL166C", "aln": "------------MSVQKEEYDIVEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTWTKDEEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFLAS--ELPGNLLSKRFGPERVIPVQIVLWSVICITQAG-LKNRGQFIATRCLLGMVQGGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSNRQPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLN-YSTFLSNILAIPGQALLLINLPLAALLSRKLKEKSLCVG---IANVWVLPFIVSLVALPTDTN---PWIKYILLTGILGLPYTHSILAGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKILLGFTCFNICMAVATKFYYISRNKYKDRKWNSMTKEEQINYLDTTKDKGMKRLDYRFIH-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .: . : . .: * : * : . . . * :: . * . . *: : . . : . . : . . ", "identical_positions": 5, "similar_positions": 29, "identity": "0.86%" }, { "cls_id": "homologset.agr.FB:FBgn0010501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55213-1", "uniprot_id": "CASP3_RAT", "id": "P55213-1", "name": "Caspase-3", "aln": "-----MDNNETS--------VDSKSINNFETKTIHGSKS-------------MDSGIYLDS--------SYKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMELMDSVSKEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSG----TDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFES-FSLDATFHAKKQIPCIVSMLTKELYFYH--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70677-1", "uniprot_id": "CASP3_MOUSE", "id": "P70677-1", "name": "Caspase-3", "aln": "-----MENNKTS--------VDSKSINNFEVKTIHGSKS-------------VDSGIYLDS--------SYKMDYPEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVSKEDHSKRSSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSG----TDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFES-FSLDSTFHAKKQIPCIVSMLTKELYFYH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42574-1", "uniprot_id": "CASP3_HUMAN", "id": "P42574-1", "name": "Caspase-3", "aln": "-----MENTENS--------VDSKSIKNLEPKIIHGSES-------------MDSGISLDN--------SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG----VDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFES-FSFDATFHAKKQIPCIVSMLTKELYFYH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H6L3-1", "uniprot_id": "A0AC58H6L3_DANRE", "id": "A0AC58H6L3-1", "name": "Caspase-3", "aln": "-----MLKQETAGEQVTMSDVKPKGVDTVDARQSDAKESSSVT---DPGLVQMDAKSHSDDNVDY----QYKTNYPNLGQCLIINNKNFHKRTGMGVRNGTDEDAKKVFETFSQLGFKVGHYNDLTVSQMMALLNKASQEDHSKSAMFACVLLSHGDDGLIYGTDNSIELKRLFAHFRGDRCTSLVGKPKLFFIQACRGTDLDSGIECDGV----GDEET--QRIPVEADFLYAYSTAPGYYAWRNVANGSWFISSLCDMLLKYGKQLEIMQVMTRVNHKVALEFES-SSNLPGFDGKKQIPCIVSMLTKELYFPK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZQU7-1", "uniprot_id": "A0A8I5ZQU7_RAT", "id": "A0A8I5ZQU7-1", "name": "", "aln": "-----MLSFYYYREE--GNSLPVAS--GGSLVLQRGLLPDGDTRKKKKNASMCPVSTTRDRVPTY----LYRMDFEKMGKCIIINNKNFDKATGMDVRNGTDKDAEALFKCFRSLGFEVTVYNDCSCAKMQDLLRRASEEDHSNSACFACVLLSHGEENLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIN-DTDANPRYKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFES-QSDDPRFNEKKQIPCMVSMLTKELYFGR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97864-1", "uniprot_id": "CASP7_MOUSE", "id": "P97864-1", "name": "Caspase-7", "aln": "-----MTDDQDCAAE--LEKVDSSSEDGVDAKPDRSSIISSILLKKKRNASAGPVRTGRDRVPTY----LYRMDFQKMGKCIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASEEDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIN-DIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFES-QSDDPRFNEKKQIPCMVSMLTKELYFSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55210-1", "uniprot_id": "CASP7_HUMAN", "id": "P55210-1", "name": "Caspase-7", "aln": "-----MADDQGCIEE--QGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTY----QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIN-DTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFES-QSDDPHFHEKKQIPCVVSMLTKELYFSQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O02002-1", "uniprot_id": "CASP1_DROME", "id": "O02002-1", "name": "Caspase-1", "aln": "MTDECVTRNYGVGIRSPNGSENRGSFIMADNTDAKGCTPESLVVGGATAASPLPANKFVARMPVERYASEYNMSHKHRGVALIFNHEFFDIPS-LKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTRILRFGDKPNGNKAG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . *. .. . * .:*:*:: *. : : *.**: ** : : * * : * :* . .: : .:: **:. :. :****:.. ::..: :. : .* . * :* *****:****:* ** ** : : :**:.****::*** ***::**. ***::.:* * ... ::: ::* ** :** .*** . . :. :*****:.****: * * ", "identical_positions": 75, "similar_positions": 82, "identity": "23.15%" }, { "cls_id": "homologset.agr.FB:FBgn0010516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13803-1", "uniprot_id": "ETFA_RAT", "id": "P13803-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCK---VAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAAA-SGGSASSEKAPS-SSSAGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC5-1", "uniprot_id": "ETFA_MOUSE", "id": "Q99LC5-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCK---VAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAAT-SGGSASSEKAPS-SSSVGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13804-1", "uniprot_id": "ETFA_HUMAN", "id": "P13804-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFR--AAAPGQLRRAASLLR-FQSTLVIAEHAND-SLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCK---VAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAAT-SGGSASSEKASS-TSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFK-LLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KN94-1", "uniprot_id": "ETFA_DROME", "id": "Q7KN94-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MF---ASNTRNLMRSSILQR-CKSTLVVAEHNNE-VLNPITLNTISAAKKIGGDVTVLVAGTKCGPASEALSK---VDGVTKVLVAENAAFNGFTAESLTPLVLAAQSQFKFTHILAGASAFGKNVLPRVAAKLDVSPISEIIDVKSDDTFVRTIYAGNAILTLKSKDAVKVITVRSTNFPPAAT-SGGSGAVEQAPAGDFASSLSEFVSQELTKSDRPELAGAKVIVSGGRGLKSGDNFK-LLYDLADKFGAAVGASRAAVDAGFVPNDLQIGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADIGIVADLFKAVPELTGKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12480-1", "uniprot_id": "ETFA_YEAST", "id": "Q12480-1", "name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "aln": "MFKSLAAVLPRASKAKFLQKNYASTLAFIESSKDGSVSRSSLSLLAAAQKLSNPITAVITGSKAEKTAEALKSSYSCSNLEKLVIFEDSKLDTCLPEQLTPLLVKLLKGGDYSHFVVSNSSVGKSVLPRVGALLDVQPVCEVTVIKDPKTFIRPIYAGNIISTIECQAEKKLLIIRASAFPPIAEGSMDSVTIEKRTDIPPCDLNVTWVKTILTKSERPELTSAQNVVTGGRALKDKETFEKLLSPLADVLHAAIGATRASVDNGLCDNSLQIGQTGKVVAPNLYIAIGVSGAVQHLAGMKDSKVIVAINNDPDAPIFNVADYGLQGDLYKIVPELTEKLGKYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: . :: * : ***.. * :: : :*. ::** ::.. :: :::*:*. . : * . .: *::: :. . .*.****:: . .::*: .. *:.**.:****.* *:* *:.:: :*. .**:*.***** : *::.. *:: :*.: * . * * .* : *: . ::. ****:****:.*: :*:***.**. :.*: ** *** : **:**:**:** *: *.:*:*****:***:****:*:***:**********.*****:**:****:*** *: .**:* ***:* * ", "identical_positions": 130, "similar_positions": 112, "identity": "37.79%" }, { "cls_id": "homologset.agr.FB:FBgn0010520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1RP75-1", "uniprot_id": "Q1RP75_RAT", "id": "Q1RP75-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "-GKQKKTRKY-----ATMKRMLSLR-DERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CTH6-1", "uniprot_id": "FCF1_MOUSE", "id": "Q9CTH6-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "MGKQKKTRKY-----ATMKRMLSLR-DERLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKFRVALRIAKDPRFDRLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYLSNHRYNIERMPDDYGAPRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y324-1", "uniprot_id": "FCF1_HUMAN", "id": "Q9Y324-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "MGKQKKTRKY-----ATMKRMLSLR-DQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKCIPCITDCVMAEIEKLGQKYRVALRIAKDPRFERLPCTHKGTYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPIMYISNHRYNIERMPDDYGAPRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL75-1", "uniprot_id": "Q9VL75_DROME", "id": "Q9VL75-1", "name": "rRNA-processing protein FCF1 homolog", "aln": "MGKHKKTQKVKKQRNAQLKRIIKPT-DARLK--DQIRVKRKKAEDPHQIKVHEATQQSSALFFQYNTQLGPPYHIVLDTNFINFSIKNKLDIVQGMMDCLYAKCIPYISDCVRAELEKLGNKYKLALRIISDPRFERLPCLHKGTYADDCLVERVRQHKCYIVATNDKDLKNRIRKIPGVPIMYVAAHKYAIERMPEAYGVKA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05498-1", "uniprot_id": "FCF1_YEAST", "id": "Q05498-1", "name": "rRNA-processing protein FCF1", "aln": "MGKAKKTRKF-----GLVKRTLNTKKDQRLK---KNQENIKTKEDPELTR--NIPQVSSALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVGGHAYVIEKLPDVF-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ***:* . :** :. * *** : : : * :** : : .* .*.****** : ***::::*********: *:*:*:.***** *** * *:*** **:**** *:::**:: ***:.**.* ***********.** ********* * .**.*******:*:* :. * * **::*: : ", "identical_positions": 105, "similar_positions": 45, "identity": "51.47%" }, { "cls_id": "homologset.agr.FB:FBgn0010531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK72-1", "uniprot_id": "CCS_RAT", "id": "Q9JK72-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MASKSGDGGTMCALEFTVQMS--CQSCVDAVHKTLKGAAGVQNVEVQLENQMVLVQTTLPSQEVQALLESTGRQAVLKGMGSSQ------LKNLGAAVAIMEGSGTVQGVVRFLQLSSEL---CLIEGTIDGL-EPGLHGLHVHQYGDLTKDCSSCGDHFNPDGASHGGPQD--TDRHRGDLGNVHAEASGRATFRIEDKQLKVWDVIGRSLVVDEGEDDLGRGGHPLSKVTGNSGKRLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGQGRKDSAQPPAHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU84-1", "uniprot_id": "CCS_MOUSE", "id": "Q9WU84-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MASKSGDGGTVCALEFAVQMS--CQSCVDAVHKTLKGVAGVQNVDVQLENQMVLVQTTLPSQEVQALLESTGRQAVLKGMGSSQ------LQNLGAAVAILEGCGSIQGVVRFLQLSSEL---CLIEGTIDGL-EPGLHGLHVHQYGDLTRDCNSCGDHFNPDGASHGGPQD--TDRHRGDLGNVRAEAGGRATFRIEDKQLKVWDVIGRSLVIDEGEDDLGRGGHPLSKITGNSGKRLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGQGRKDSAQPPAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14618-1", "uniprot_id": "CCS_HUMAN", "id": "O14618-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MASDSGNQGTLCTLEFAVQMT--CQSCVDAVRKSLQGVAGVQDVEVHLEDQMVLVHTTLPSQEVQALLEGTGRQAVLKGMGSGQ------LQNLGAAVAILGGPGTVQGVVRFLQLTPER---CLIEGTIDGL-EPGLHGLHVHQYGDLTNNCNSCGNHFNPDGASHGGPQD--SDRHRGDLGNVRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGRKESAQPPAHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JH26-1", "uniprot_id": "CCS_DROME", "id": "E1JH26-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MSS--------IKIEFAVQMRRGDESYAGALRSALDGVG---QVEIDTQEGRVIIQTQRPWSEIQDKIEATGVRAVLSGFGGQS------AVALINTTGSVVDKTPIQGVVRFTTITADKKPGVVVDGVVDGL-SPGLHGLHIHESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIGRAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERNKPLAGKERSQKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40202-1", "uniprot_id": "CCS1_YEAST", "id": "P40202-1", "name": "Superoxide dismutase 1 copper chaperone", "aln": "MTTN-----DTYEATYAIPMH--CENCVNDIKACLKNVPGINSLNFDIEQQIMSVESSVAPSTIINTLRNCGKDAIIRGAGKPNSSAVAILETFQKYTIDQKKDTAVRGLARIVQVGENK---TLFDITVNGVPEAGNYHASIHEKGDVSKGVESTGKVWHKFDEPIECFNE-------SDLG-----KNLYSGKTFLSAPLPTWQLIGRSFVISKS---LNHPENEPSSVKDYS----FLGVIARSAGVWENNKQVCACTGKTVWEERKDALANNIK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ::: * :. .. :: *... .::.. :: : :.: . . : :. * *:: * * . : . .::*:.*: : : :.: .::*: ..* : :*: ** : . .* *. :: . .*** . : : . * .*::***:.:: . *.: : * : . * *:******: :* *::*:* * *:*:** .:*.: : ", "identical_positions": 44, "similar_positions": 93, "identity": "15.28%" }, { "cls_id": "homologset.agr.FB:FBgn0010548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VQ0-1", "uniprot_id": "AL3B1_MOUSE", "id": "Q80VQ0-1", "name": "Aldehyde dehydrogenase family 3 member B1", "aln": "------------------------------------------------------------------MDSFEDKLQQLREAFKE----------GRTRSAEFRAAQLQGLSHFLRDNKQQLQEALAQDLHKSAFEAEVSEIAISQAEVDLALRNLRSWMKDEKVS-KNLATQLDSAFIRKEPFGLVLIIVPWNYPINLTLVPLVGAIAAGNCVVLKPSEISKATEKILAEVLPRY-LDQSCFTVVLGGRQETGQLLEH-KFDYIFFTGNAYVGKIVMAAAAKHLTPITLELGGKNPCYVDD---NCDPQIVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNAITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCG--------RVAIGGQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAI-EFMNRREKPLALYAFSKRSQVIKQVLARTSSGGFCGNDGFMHMTLSSLPFGGVGTSGMGRYHGKFSFDTFSNQRACLLR--SPGMEKINDLRYPPYSSRNLRVLLVAMEERC----------------CSCTLL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI42-1", "uniprot_id": "AL3B1_RAT", "id": "Q5XI42-1", "name": "Aldehyde dehydrogenase family 3 member B1", "aln": "------------------------------------------------------------------MDSFEDKLQQLREAFNA----------GRTRSAEFRAAQLQGLSHFLRDNKQQLQEALAQDLHKSAFESEVSEIAISQAEVDLALRNLRSWMKDEKVS-KNLATQLDSAFIRKEPFGLVLIIVPWNYPLNLTLVPLVGAIAAGNCVVLKPSEISKATEKILAEVLPRY-LDQSCFAVVLGGPQETGQLLEH-RFDYIFFTGNTYVGKIVMAAAAKHLTPITLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSQEMQERLVPALQNAITRFYGDNPQTSPNLGRIINQKHFERLQGLLGCG--------RVAIGGQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVTNLDEAI-EFINRREKPLALYAFSKRSQVIKQVLARTSSGGFCGNDGFMHMTLSSLPFGGVGTSGMGRYHGKFSFDTFSNQRACLLR--SPGMEKINDLRYPPYTSRNLRVLLVAMEKRC----------------CSCTLL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43353-1", "uniprot_id": "AL3B1_HUMAN", "id": "P43353-1", "name": "Aldehyde dehydrogenase family 3 member B1", "aln": "------------------------------------------------------------------MDPLGDTLRRLREAFHA----------GRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMKDERVP-KNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY-VDQSCFAVVLGGPQETGQLLEH-RFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCG--------RVAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAI-EFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLR--SPGMEKLNALRYPPQSPRRLRMLLVAMEAQG----------------CSCTLL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q3E1-1", "uniprot_id": "AL3B2_MOUSE", "id": "E9Q3E1-1", "name": "Aldehyde dehydrogenase family 3 member B2", "aln": "-----------------------------------------------------MSAAETGSEPSQGAGPSEATLHSLREAFNA----------GRTRPTEFRTAQLRSLGRFLQENKELLQDALAKDVGKSGFESDMSEIILCENEVDLALKNLQTWMKDEPVS-TNLLTKLSSAFIRKEPFGLVLIIAPWNYPVNLMIIPLVGAIAAGNCVVLKPSEISKNTEKVLAELLPQY-LDQSCFAVMLGGPEETRQLLEH-KFDYIFFTGSPRVGKIVMTAAAKHLTPITLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNSITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCG--------RVAIGGQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAI-EFINRREKPLALYAFSNNNQVVNQMLERTSSGGFGGNDGFLYLTLPALPLGGVGNSGMGRYHGKFSFDTFSHHRACLLR--SPGMEKLNDLRYPPYGPWNQQLISWAIGSR------------------SCTLL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QMK6-1", "uniprot_id": "AL3B3_MOUSE", "id": "J3QMK6-1", "name": "Aldehyde dehydrogenase family 3 member B3", "aln": "-----------------------------------------------------MSTKGKHPRADQGTDPFEEKLQRLKEAFNT----------GKTKTAKFRAEQLQSLGRFLQDNSKQLHDALDGDLGKSGFESDMSEIILCENEVDLALKNLQTWMKDEPVS-TNLLTKLSTAFIRKEPFGLVLIIAPWNYPVNLMIIPLVGAIAAGNCVVLKPSEISKNTEKVLAELLPQY-LDQSCFAVMLGGPEETGQLLEH-KFDYIFFTGSPRVGKIVMTAAAKHLTPITLELGGKNPCYVDD---NCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQEQLVPALQNAITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCG--------RVAIGGQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAI-EFMNQREKPLALYAYSNNAEVIKQVLARTSSGGFCGNDGFMYMTLSSLPFGGVGSSGMGRYHGKFSFDTFSNQRACLLS--CPGMEKLNGLRYPPYSPRRQQLLRWAIGSE------------------SCTLL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48448-1", "uniprot_id": "AL3B2_HUMAN", "id": "P48448-1", "name": "Aldehyde dehydrogenase family 3 member B2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKDEPRS-TNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQSCFAVVLGGPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDD---NCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRALLGCS--------RVAIGGQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAI-KFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLA--PSGLEKLKEIHYPPYTDWNQQLLRWGMGSQ------------------SCTLL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DHC8-1", "uniprot_id": "A0A0C4DHC8_DROME", "id": "A0A0C4DHC8-1", "name": "", "aln": "MFDNAIKPHPEANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSS----------GKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPP-KSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCGGPSETAELLNQ-RFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDK---SVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSG--------RVAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAI-KFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRPLPNLHLSHVLAIGLGVGLTVLTNYYLQGKLLSK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47740-1", "uniprot_id": "AL3A2_MOUSE", "id": "P47740-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVLRLRQAFRS----------GRSRPLRFRLQQLEALRRMVQEREKEILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAK-KNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTMQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYAIVNGGIPETTELLKQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRIAWGKYMNCGQTCIAPDYILCEASLQNQIVQKIKETVKDFYGENIKASPDYERIINLRHFKRLQSLLKGQ--------KIAFGGEMDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAI-NFINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLK--GLKGESVNKLRYPPNSESKVSWAKFFLLKQFNKGRLG------MLLFVCLVAVAAVIVKDQL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30839-1", "uniprot_id": "AL3A2_RAT", "id": "P30839-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVQRLRQTFRS----------GRSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAK-KNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYMIVNGGVEETTELLRQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRITWGKYMNCGQTCIAPDYILCEASSQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKSLLEGQ--------KIAFGGETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAI-NFINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLK--GLKGESVNKLRYPPNSESKVSWSKFFLLKQFNKGRLQ------LLLLVCLVAVAAVIVKDQL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51648-1", "uniprot_id": "AL3A2_HUMAN", "id": "P51648-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MELEVRRVRQAFLS----------GRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDFMLENLPEWVTAKPVK-KNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQ-RFDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDK---DCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQ--------KIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAI-NFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLK--SLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLG------LLLLTFLGIVAAVLVKAEYY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47739-1", "uniprot_id": "AL3A1_MOUSE", "id": "P47739-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSNISSIVNRARDAFNS----------GKTRPLQFRVEQLEALQRMINENLKGISKALASNLRKNEWTSYYEEVAHVLDEIDFTIKGLSDWAEDEPVA-KTRQTQEDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAIAAGNAVVLKPSEVSDHMADLLSTLIPQY-MDKDLYPVIKGGVPETTELLKE-KFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNEIVEKLKKSLKDFYGEDAKQSHDYGRIINDRHFQRVINLIDSK--------KVAHGGTWDQPSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLDEAI-KFINQREKPLALYVFSNNDKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVR--SLRNEEANKARYPP-SPAKMPRH-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11883-1", "uniprot_id": "AL3A1_RAT", "id": "P11883-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSSISDTVKRAREAFNS----------GKTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVA-KTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLKE-RFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQ--------KVAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAI-QFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVK--SLLNEEAHKARYPP-SPAKMPRH-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30838-1", "uniprot_id": "AL3A1_HUMAN", "id": "P30838-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSKISEAVKRARAAFSS----------GRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVE-KTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE-RFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDK---NCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQ--------KVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAI-QFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVR--PLMNDEGLKVRYPP-SPAKMTQH-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B720-1", "uniprot_id": "A0ACD6B720_DANRE", "id": "A0ACD6B720-1", "name": "Aldehyde dehydrogenase", "aln": "--------------------------------------------------------------------MEKQVVDGLREVFQS----------GRSRPLQYRKQQLRALLRLITERHADIEQALKQDLNRSMHGTSLFELIGIENDIKVAEREMTEWAAPRPVK-KNLNSALDDVYVKPEPLGVVLIIGTWNYPWAMIFQPLVGAIAAGNAAVVKPSELSEHSSRLMKELLPLY-LDKEMYQVVTGGVPETQELLKQ-RFDHIFYTGSSTVGKLVMEAASRHLTPVTLELGGKSPCYIDK---NCDIAVACRRITWGKFANCGQTCIAPDYILCEPSIQDRIVEEIQKTLLEFYQTDPKSSPDYCRIINTRHFDRVLALMNEC--------TIALGGENDRSQCYIAPTVLKDVLPHFKIMQEEIFGPLLPIVTVNGLSEAI-NFINAREKPLALYVFSSDKTVIKRMLKETTSGGVTVNDVLMHYTVDTLPFGGVGNSGMGRYHGKHTFDQLSHHRACLIK--SFAMESLNDARYPPLTTARLRKAKFFMGHRMCSCNGM------CVWAVIATVLAIGLLVGLLVVLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04458-1", "uniprot_id": "HFD1_YEAST", "id": "Q04458-1", "name": "Fatty aldehyde dehydrogenase HFD1", "aln": "-----------------------------------------------------MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYP-SFDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISIN-SDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQ--PYWNDFTLFMRYPPNSAQKEKLVRFAMERKPWFDRNGNNKWGLRQYFSLSAAVILISTIYAHCSS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : . * **:* .:*:* : : : .*:***. ::****:: .: ::. . . :: *. ** .** ::* *::**.. **.:: * : *** .******.* :: : . .*: : *.** *::***:* . ..: :. : :* . . . : ::* :.: : :: . : **:: :: :*::* *.*::*:. . ::* :::: ::.**. * :* ::.. **. .: . : : *:**:* ** * * * *: :::.:. : : :*** . ", "identical_positions": 74, "similar_positions": 123, "identity": "12.54%" }, { "cls_id": "homologset.agr.FB:FBgn0010549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M3J4-1", "uniprot_id": "MRP4_RAT", "id": "F1M3J4-1", "name": "ATP-binding cassette subfamily C member 4", "aln": "-------------------------------------------------------------------MLPVHTEVK-----------PNPLQDANLCSRLFFWWLNPLFKAGHKRRLEEDDMFSVLPEDRSKHLGEELQGYWDKEVLRAKKDARKPSLTKAIVKCYWKSYLILGIFTLIEET-TRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAVLSLCTLILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTTYVLLGNKITASHVFVAMTLYGAVRLTVTLFFPSAIERVSEAVVSVRRIKNFLLLDELPERKAQEPSDGKA-----------------IVHVQDFTAFWDKALDTPTLQGLSFTARPGELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVHGRIAYVSQQPWVFSGTVRSNILFGRKYEKERYEKVIKACALKKDFQLLEDGDRLVIGDRGARLSGGQKARVNLATAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSG--VDFGSLLKKENEEAEPSPVPGTP-TLRNRTFSEASIWSQQSSRPSLKDGVPDAQDAENTQAAQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNLMGQVFYVLQDWWLSHWANRQGALNDTKN-------ANGNVTGTLDLSWYLGIYTGLTAVTVLFGIARSLLVFYVLVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSIIFVVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFGSLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECR--KRPPPGWPHEGVIVFDNVNFTYSL--DGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHSDEELWKALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYDEPYVLLQNPES-LFYKMVQQLGKGEAAALTETAKQVYFRRNYPDIAFSSPAVMSTSNGQPSALTIFETAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q236-1", "uniprot_id": "MRP4_MOUSE", "id": "E9Q236-1", "name": "ATP-binding cassette sub-family C member 4", "aln": "-------------------------------------------------------------------MLPVHTEVK-----------PNPLQDANLCSRVFFWWLNPLFKTGHKRRLEEDDMFSVLPEDRSKHLGEELQRYWDKELLRAKKDSRKPSLTKAIIKCYWKSYLILGIFTLIEEG-TRVVQPLFLGKIIEYFEKYDPDDSVALHTAYGYAAVLSMCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAGLAVLVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIANLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGAVRLTVTLFFPSAIERGSEAIVSIRRIKNFLLLDELPQRKAHVPSDGKA-----------------IVHVQDFTAFWDKALDSPTLQGLSFIARPGELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSG--VDFGSLLKKENEEAEPSTAPGTP-TLRKRTFSEASIWSQQSSRPSLKDGAPEGQDAENTQAVQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNMVGQVFYVLQDWWLSHWANKQGALNNTRN-------ANGNITETLDLSWYLGIYAGLTAVTVLFGIARSLLVFYILVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFVIVVAFGSLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECK--KRPPPGWPHEGVIVFDNVNFTYSL--DGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWRALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKNNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNPES-LFYKMVQQLGKGEAAALTETAKQVYFRRNYPDITFTSPAVMNTSNGQPSALTIFETAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15439-1", "uniprot_id": "MRP4_HUMAN", "id": "O15439-1", "name": "ATP-binding cassette sub-family C member 4", "aln": "-------------------------------------------------------------------MLPVYQEVK-----------PNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEES-AKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKK-----------------MVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSG--IDFGSLLKKDNEESEQPPVPGTP-TLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVN-------GGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQ--KRPPPAWPHEGVIIFDNVNFMYSP--GGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKES-LFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2Y9-1", "uniprot_id": "A0A8M1N2Y9_DANRE", "id": "A0A8M1N2Y9-1", "name": "Cystic fibrosis transmembrane conductance regulator", "aln": "---------------------------------------------------------------MTSDMEPIKKDAK-----------SNPSASANLFSQIFFCWLNPLFSIGSKRRLEEDDMFNVLPEDRSKKLGEELQSYWDQEKEKAAKELKTPKLTKAIIRCYWKSYAVLGVFTLIEES-IKVIQPVFLGKLIKYFENYRHDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQTTTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMFGKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYLRGLNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISIRRIKKFLLLDELVKNHLPLSQEEKKEP---------------SVEMQDLICYWDKTLDAPTLQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFPGTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGSYSELQQSG--LDFTSLLKKDEEEESGSEKGEAPRSPRSRTVSQNSVRSHSSSVLSVKDDS--DQLPAEPVHTMAEELRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDHNTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAEMLHNRMFNSILRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLPLLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHSEAWFLFLTTSRWFAVRLDGMCSVFVTITAFGCLLLKDTMNAGDVGLALSYAVTLMGMFQWGVRQSAEVENMMTSVERVVEYTELESEAPWETQ--KRPSPDWPNRGLITFDRVNFSYSS--DGPVVLKNISAMFRPREKVGIVGRTGAGKSSLISALFRLSEPEGKILVDGVLTSEIGLHDLRQKMSIIPQDPVLFTGTMRKNLDPFNQHSDHDLWKALEEVQLKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAILRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYDAPHVLLQNQSG-IFYKMVQQTGKAEATSLLQTAKQAYANR---SPAHQLNGFATTGDG---SLIIFETAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91660-1", "uniprot_id": "L259_DROME", "id": "P91660-1", "name": "Probable multidrug resistance-associated protein lethal(2)03659", "aln": "MDKQPVLEPTFDSVSERENTSIEESSLLENNGFDHRNKDESLSVNTSPPLVCRKCFELGHQTENCKQKLTVNSENNSAQNEKEKVLPENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCASWERELK---NDGRSPSLVRALLRVFGWQLGFPGLAIFVVELGLRTLQPIFLVKLISYFS----GEPDAANAGFYYAVAQIVISALTVMILTPTTFGIHHVCFKMRVAMGSMIFRKALRLTKGALGDTTSGHVVNLISNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQLKAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRIVLSRVAIFLSLVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSEELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFSGTVRQNILFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLLKTGLITGLGSLSKTDKAKTEEQE----PLNLNSP--------DNKNEVTPIKENSEQTVGGSSSGKEHVERQES-GGISLALYRKYFQAGGGLVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKES---TAAG--------HGEMEDMESKSMDVYKYTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSILNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYISTSQAFGYCMNCICVIYISIITLSFFAFP-PGNGADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERVVEYESIEPEGMLEAPDDKKPPKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFRLSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLDPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKVFHNLVNQSGRASYEGLLKIAQETFESS------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : ** :*: * : * : *:* * :: *:. *:: * *::*. **:.* *::* :: :.*.*.:*::: : . . *: :: * :.:**:** *:*.**. : * .: **. . : .:: : :: . :::*:** **:**** *: *:*.**:*::***:***: ::*. . :*:**.****. : *:: *** *.: *: .:::::*:* :*. * : *:* ** *** :**:::.::::******:.* :: . *.**:..* .. :**:::* : .:: :*:::. **::*. ::.. .*: : *..: :::::.*:** : :: *:**:: *: :*: . . . . : ::*: . ** **..: : :**.::**:* .*:*****:.::**** . * :.*:* ::*.**:.*:*.**:*.*****: : :***.*:: ***::*::** * ::*:**: ********:.** :**:.*.*************.*.:***: *: *: . :***** *:* ..:*::* :*.: * * .: ::* .: ** *.:: : . * . .. .:... .:*:. . *. .* * :.: * :** **. . ::.:: . .*. *::*::*...: . *: . . : *: : ::::.: .:::* .:: *** :*: : :: : **. * * *****:**:.::*.:** .::*.:* * :..:: * * * : :* : * : * **. :*.****:**:*: .****:***::**:** **** .*:. :: **::** **.*:*::::**: *. :: :* ::: : ::. : : . :..:***.:: :: *:.*.** ***:**:** * :****:** .:* *. * *:*. **..* * *..:*: *: . *** :: :::.:*****************.****** .:*.: :* * ::******:::*****:****:**** *****::::*..** .*:**:** .:.:**. : ::::*.*:*****************::*::*::*********:** *** .**.** .**********:******:::*:*:**: *:. *: *: : .. :*:::*:* *:.. .* : *::.: ", "identical_positions": 454, "similar_positions": 475, "identity": "31.62%" }, { "cls_id": "homologset.agr.FB:FBgn0010551", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99623-1", "uniprot_id": "PHB2_HUMAN", "id": "Q99623-1", "name": "Prohibitin-2", "aln": "----------------MAQN-LKDLAGRLP-AGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLN-LQDESFTRGSDSLIKGKK--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35129-1", "uniprot_id": "PHB2_MOUSE", "id": "O35129-1", "name": "Prohibitin-2", "aln": "----------------MAQN-LKDLAGRLP-AGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLN-LQDESFTRGSDSLIKGKK--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIH7-1", "uniprot_id": "PHB2_RAT", "id": "Q5XIH7-1", "name": "Prohibitin-2", "aln": "----------------MAQN-LKDLAGRLP-SGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLN-LQDESFTRGSDSLIKGKK--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1R9C6-1", "uniprot_id": "F1R9C6_DANRE", "id": "F1R9C6-1", "name": "Prohibitin", "aln": "--------MANKEPSRFLQN-LRDLMGRIS-SGSRGAGIGLKLLIGAGALAYGVREATYTVEGGQRAIIFNRIGGVQLDTVLTEGLHFRIPWFQYPIIYDIRARPRKISSLTGSKDLQMVNIALRVLSRPLASNLPIMYQQLGQDYDERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELFERAKDFNIILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFFVEKAKQEQKQKIIQAEGEAQAAKMLGEAVTKNPGYLKLRRIRAAQNIAKTVAASQNKVYLSADSLVMN-LQDDSFNK----LSLGKK--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYI6-1", "uniprot_id": "A8DYI6_DROME", "id": "A8DYI6-1", "name": "Prohibitin", "aln": "----------------MAQSKLNDLAGKLGKGGPPGLGIGLKVLAAVGAAAYGVSQSLYTVEGGHRAIIFSRLGGIQSD-IYSEGLHVRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLN-IQDSGFDDMTEKVYKIGTGLPKDWLDARKMASKVAQPAEKEKNVGNVASSMAERMM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50085-1", "uniprot_id": "PHB2_YEAST", "id": "P50085-1", "name": "Prohibitin-2", "aln": "MNRSPGEFQRYAKAFQKQLSKVQQTGGRGQVPSPRGAFAGLGGLLLLGGGALFINNALFNVDGGHRAIVYSRIHGVSSR-IFNEGTHFIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAKSAELIGEAIKKSRDYVELKRLDTARDIAKILASSPNRVILDNEALLLNTVVDARIDG------RGK---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: *: .. * .* * *. * : :: :.*:**:***.:.*: *:. : ** *. :**:: *****:*::**:::* **:*****:**: ****** :** ::: ** **:*:***** *****:*:*:********** :** ***.:* .** .*.::****::* ::*. *:* *:****:***:**** *.*::*:**:: :::*:***::*:::* *:.:. *::*::: :*:.*:: :*:* *:: * : *::* : * : ", "identical_positions": 124, "similar_positions": 100, "identity": "34.83%" }, { "cls_id": "homologset.agr.FB:FBgn0010583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ33-1", "uniprot_id": "B2RZ33_RAT", "id": "B2RZ33-1", "name": "Cytoplasmic protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPD-TASPAD-DSFVDPGE----------RLYDLNMPAFVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQIGWFPSNYVTEEGDSPLGD--------HVGSLSEKLAAVVNNLN----TGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLT---------------------------SGLE-PS----PPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M51-1", "uniprot_id": "NCK1_MOUSE", "id": "Q99M51-1", "name": "SH2/SH3 adapter protein Nck1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPD-TASPAD-DSFVDPGE----------RLYDLNMPAFVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQIGWFPSNYVTEEGDSPLGD--------HVGSLSEKLAAVVNNLN----TGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTIMQNNPLT---------------------------SGLE-PS----PPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16333-1", "uniprot_id": "NCK1_HUMAN", "id": "P16333-1", "name": "SH2/SH3 adapter protein NCK1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPD-SASPAD-DSFVDPGE----------RLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGD--------HVGSLSEKLAAVVNNLN----TGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLT---------------------------SGLE-PS----PPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6M0-1", "uniprot_id": "E7F6M0_DANRE", "id": "E7F6M0-1", "name": "Cytoplasmic protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKFDYMAQQDQELDIKKNERLWLLDDSKSWWRVRNATNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKTGMRE-TASNADSDFYPDNGE----------RLYDLNLPALVKFSYAAEREDELSLVKGTRVIVMEKCSDGWWRGSYNGRSGWFPSNYVTEDADGSASN--------DSAGLSDKLSAVVQSAN----GNRVLHTVQALYPFSSGNDEELNFEKGEVMDVVEKPENDPEWWKCRKSDGQMGLVPKNYVTVLQESHNS---------------------------ASMPGPP----TPDCDYIEPSSSGRFAGKQWYYGKVTRHQAEVALNQRGSEGDFLIRDSESSPNDFSISLKAQSKNKHFKVQLKDNLYCIGQRKFNTMEELVEHYKKAPIFTSEQGDKLYLVKALAAS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TBD0-1", "uniprot_id": "A0A8N7TBD0_DANRE", "id": "A0A8N7TBD0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMANLFKHFFRIGKVKQKGCVRD-LPSSAE---KYEGDE----------RLYDLNLPALVKFNYTAEREDELSLVKGTRVIVMEKCSDGWWRGSYNGLSGWFPSNYVTEDVDGTMRV--------DSVNP-DKLASVGHNNN----SSQVLQTVQALYHFSSGNVEELNFNKYELMDVLEKPENDPEWWKCRKENGQVGLVPKNYVTVVQKTHKE---------------------------LGISGPH----PSNYD-IKPSMDGKFGGKQWYYGKLTRHQAEMVLNQRGVDGDFLIRDSESMPNDFSISLKALYKNKHFKVLLNDGFFCIGQRKFSTMEDLVEHYKKAPIFTSEHGDKLYLIKPLT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A3M8-1", "uniprot_id": "D4A3M8_RAT", "id": "D4A3M8-1", "name": "Cytoplasmic protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKPSARDASPTPSTDAEYPANGS-------GADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSFNGQIGWFPSNYVLEEADEAAAE------APSFLSLRRG--TALSNGQ----GARVLHVVQTLYPFSSVTEEELSFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGP------------------------------ALHPTH----TPQISYTGPSASGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGRNKHFKVQLVDSVYCIGQRRFHSMDELVEHYKKAPIFTSEHGEKLYLVRALQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55033-1", "uniprot_id": "NCK2_MOUSE", "id": "O55033-1", "name": "Cytoplasmic protein NCK2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKPSARDASPTPSTDAEYPANGS-------GADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSFNGQIGWFPSNYVLEEADEAAAE------APSFLSLRRG--TALSNGQ----GARVLHVVQTLYPFSSVTEEELSFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGP------------------------------ALHPAH----TPQISYTGPSASGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGRNKHFKVQLVDSVYCIGQRRFHSMDELVEHYKKAPIFTSEHGEKLYLVRALQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43639-1", "uniprot_id": "NCK2_HUMAN", "id": "O43639-1", "name": "Cytoplasmic protein NCK2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGS-------GADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAE------SPSFLSLRKG--ASLSNGQ----GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGP------------------------------ALHPAH----APQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPIFTSEHGEKLYLVRALQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4I8-1", "uniprot_id": "A0A8M9Q4I8_DANRE", "id": "A0A8M9Q4I8-1", "name": "Cytoplasmic protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNASNRTGYVPSNYVERKNSLKKTSLVKNLKDTLGLGKTKRKTSARDPSPTPSTEAEYPSNGSAGGGGGGGAERIYDLNIPALVKFSYAAERDDELNLVKGERVVVMEKCSDGWWRGSHAGRVGWFPSNYVQEEVGYTDNDGVFGDTVGGFRSLKVGQGSAMANGRPGGSGSSVLHVVQTLYPFSSVTEEELNFEKGETMEVLEKPENDPEWWRCKNSRGIVGLVPKNYVVVLDDGPVA---------------------------KGLGSSHG---SPHISHTVPSRVGKFAGKGWYYGNVTRHHAECALNERGVEGDFLIRDSESSPSDFSISLKAVGKNKHFKVQHQDGVYCIGQRRFSSMDELVEHYKKAPIFTSEQGDKLYLVKALG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPW2-2", "uniprot_id": "NCK_DROME", "id": "Q8IPW2-2", "name": "SH2/SH3 adapter protein dreadlocks", "aln": "MLEHPQRFVRNIPDSSASSQQYPQQQQHPPQLPQHQNLNLNQNQNLNQNQIYQYRPQVPVPVPGSPAHHQRHSSLSQQQQLHHHRTLSTASSCSAQHKSVTFGQPALDCGGNGSGSANGSGSGNSSSGSAAGNAGTQSMAGNMKHGKSQDDVCYVVAKYDYAAQGAQELDLRKNERYLLLDDSKHWWRVQNSRNQSGYVPSNYVKKEKPSLFDSIKKKVKKGSGS-KTLPNCSPSRQVESPTMSRRLPPDPA-------------EAIGTAVVKYNYQAQQPDELSLTKGTRILILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDN-----------------DGEIHTYAMAEN-------VLDIVVALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRNASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQRKFHSLDQLVDHYQRAPIYTNKQGEKLYLVRSLPKANGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : .*. *. : : : : .* **: * *:: ***.* ** :: ::**..******. . *******. *: . : . **. * :** *:* . :**.*:* : ::::::* .**:*::.:: * :****:**: :.. .: .. . * .:.*. **** :** :.: .** :* :*********: .*:*:**** :****:* : .:*****:* ::::**:**::***:*.::*:****:: * ", "identical_positions": 102, "similar_positions": 95, "identity": "17.41%" }, { "cls_id": "homologset.agr.FB:FBgn0010590", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28073-1", "uniprot_id": "PSB6_RAT", "id": "P28073-1", "name": "Proteasome subunit beta type-6", "aln": "-MAAALAVRGAVSAPAFGPEALTPDWENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVIRLAAIQQSGVERQVLLGDQIPKVTISTLPPP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JSL0-1", "uniprot_id": "A0A0G2JSL0_RAT", "id": "A0A0G2JSL0-1", "name": "Proteasome subunit beta", "aln": "-MAAALAVRGAISAPAFGPEALTPDWENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVIRLAAIQQSGVERQVLLGDQIPKVTISTLPPP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60692-1", "uniprot_id": "PSB6_MOUSE", "id": "Q60692-1", "name": "Proteasome subunit beta type-6", "aln": "-MAAALAVRRAGSAPAFGPEALTPDWENREVSTGTTIMAVQFNGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVIRLAAIQESGVERQVLLGDQIPKFTIATLPPP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28072-1", "uniprot_id": "PSB6_HUMAN", "id": "P28072-1", "name": "Proteasome subunit beta type-6", "aln": "MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28076-1", "uniprot_id": "PSB9_MOUSE", "id": "P28076-1", "name": "Proteasome subunit beta type-9", "aln": "------MLRAGAPTAGS--------FRTEEVHTGTTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYGT-MGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYLVTITAAGVDHRVILGDELPKFYDE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28077-1", "uniprot_id": "PSB9_RAT", "id": "P28077-1", "name": "Proteasome subunit beta type-9", "aln": "------MLQAGAPTAGS--------FRTGEVHTGTTIMAVEFDGGVVVGSDSRVSAGAAVVNRVFDKLSPLHQRIYCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANIVKNISYKYREDLLAHLMVAGWDQHEGGQVYGT-MGGMLIRQPFAIGGSGSTYIYGYVDAAYKPGMTPEECRRFTTDAITLAMNRDGSSGGVIYLVTITADGVDHRVILGDELPKFYDE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28065-1", "uniprot_id": "PSB9_HUMAN", "id": "P28065-1", "name": "Proteasome subunit beta type-9", "aln": "------MLRAGAPTGDL--------PRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGT-LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYDE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUS3-1", "uniprot_id": "Q9PUS3_DANRE", "id": "Q9PUS3-1", "name": "Proteasome subunit beta", "aln": "------MSEELFPEPG---------WLSEEVKTGTTIIAVTFDGGVVIGSDSRVSAGESVVNRVMNKLSPLHDKIYCALSGSAADAQTIAEIVNYQLDVHSIEVEDDPLVCSAATLVKNISYKYKEELSAHLIVAGWDKKGGGQVYAT-LSGLLTKQPFAIGGSGSFYINGFVDAEYKKNMTKRECQEFVVNALTLAMGRDGSSGGVAYVVTIDKDGTEEKCVLGNELPKFFDE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38624-1", "uniprot_id": "PSB1_YEAST", "id": "P38624-1", "name": "Proteasome subunit beta type-1", "aln": "-------MNGIQVDINR--------LKKGEVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPS-TETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0AQH0-1", "uniprot_id": "A0AQH0_DROME", "id": "A0AQH0-1", "name": "Proteasome subunit beta", "aln": "----------MQPDFD---------FTDTPVSTGTTIMAVEFDGGVVIGADSRTSSGAYVANRVTDKLTRITDKVYCCRSGSAADTQAIADIVAYSLNYHENQTNKDALVFEAASEFRNYCYSYRESLLAGIIVAGWDEQRGGQVYSIPLGGMLTRESCTIGGSGSSFIYGFVREHYRPNMALEDCVTFVKKAVQHAIYHDGSSGGVVRIGIITKDGIERRIFYNTESGASAVSSTPSFISSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:*:** *..**::*:***.::* :.*** :**: : ::::*. ******:*::*: . * * : : . . **. .:: .* ::.* * :::**:* : *:** :.* : : . :*.**** :* *: :: .*: : * .:: *: ******* : : * :. . : ", "identical_positions": 60, "similar_positions": 67, "identity": "24.69%" }, { "cls_id": "homologset.agr.FB:FBgn0010591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHN6-1", "uniprot_id": "SGPL1_RAT", "id": "Q8CHN6-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPSTDLLKLKDFEPYLEILEAYSTKAKNYVNGYCTKYEPWQ------LIAGSVLCTLLVVWVYELIFQPESLWSR----FKNKLFRLIRKMPFIGRKIQQQLTKAKKDLVKNMPFLKLDKDYVKTLPAQGLSTAEVLERLKEY-SSMDVF-WQEGKASGAVYSGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDS-CGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVAQK-KNMEVDVRAMKRAISRNTAMLVCSAPQFPHGVIDPIPEVAKLAVKYKIPFHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRKYQFFVDADWQGGIYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQATIDRKMVAEISSVFLDSLYSTDPVTQGNQMNGSPKPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0X7-1", "uniprot_id": "SGPL1_MOUSE", "id": "Q8R0X7-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPGTDLLKLKDFEPYLEILESYSTKAKNYVNGYCTKYEPWQ------LIAWSVLCTLLIVWVYELIFQPESLWSR----FKKKLFKLIRKMPFIGRKIEQQVSKAKKDLVKNMPFLKVDKDYVKTLPAQGMGTAEVLERLKEY-SSMDGS-WQEGKASGAVYNGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDS-CGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVALK-KNMEVDVQAMKRAISRNTAMLVCSTPQFPHGVMDPVPEVAKLAVRYKIPLHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLDCLYTTDPVTQGNQMNGSPKPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95470-1", "uniprot_id": "SGPL1_HUMAN", "id": "O95470-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPSTDLLMLKAFEPYLEILEVYSTKAKNYVNGHCTKYEPWQ------LIAWSVVWTLLIVWGYEFVFQPESLWSR----FKKKCFKLTRKMPIIGRKIQDKLNKTKDDISKNMSFLKVDKEYVKALPSQGLSSSAVLEKLKEY-SSMDAF-WQEGRASGTVYSGEEKLTELLVKAYGDFAWSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDS-CGCVTSGGTESILMACKAYRDLAFE-KGIKTPEIVAPQSAHAAFNKAASYFGMKIVRVPLT-KMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLDSLYSTDTVTQGSQMNGSPKPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V7Y2-1", "uniprot_id": "SGPL_DROME", "id": "Q9V7Y2-1", "name": "Sphingosine-1-phosphate lyase", "aln": "---------------------MRPFS-----GSDCLKPVTEGINRAFGAKEPWQ------VATITATTVLGGVWLWTVICQDENLYIR----GKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHLTYSETLPEKGLSKEEILRLVDEH-LKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKMEAEVVRMACNLFHGNSAS-CGTMTTGGTESIVMAMKAYRDFAREYKGITRPNIVVPKTVHAAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINRNTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLR-PFDFEVKGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWATMMSFGYDGYLEATKRIVDTAR-YIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMK--DPGQPVVGKMALYGMAQSIPDRSVIGEVTRLFLHSMYYTPSQK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05567-1", "uniprot_id": "SGPL_YEAST", "id": "Q05567-1", "name": "Sphingosine-1-phosphate lyase", "aln": "MSGVSNKTVSINGWYGMPIHLLREEGDFAQFMILTINELKIAIHGYLRN-TPWYNMLKDYLFVIFCYKLISNFFYLLKVYGPVRLAVRTYEHSSRRLFRWLLDSPFLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEELNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVFPAVRKMESEVVSMVLRMFNAPSDTGCGTTTSGGTESLLLACLSAKMYALHHRGITEPEIIAPVTAHAGFDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINKNTILLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGCWATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAH--VVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLDALYKLGPGEDTATK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . :: ** : . : .: : * * ..: *: . * : :: :: *.*..: :: . . ** :*: ::. :.: *::*:.**:** .* .* . .* . :* **.*:**.: *:*:*:* :. :*:. . : ** *:*****:::* : : * . :**. *:*:.* :.**.*:*.. **.::: * :**: .:: *.:** :** *:*:**:* * : :. :. :*.:*.***:***.*:: ::.:*** :**.* ******.******:******:::* :.. : :*: * . * **:*.**:: ***.*.* ..***::: :* :**:*: :.*: :* : : .:* .: ::*.* ***::.*. ::*..**: : **::* ** * .:*:..* : :: *. :: :* . :: . :. * *:**:* : : :: **..:* . ", "identical_positions": 150, "similar_positions": 195, "identity": "25.04%" }, { "cls_id": "homologset.agr.FB:FBgn0010602", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63279-1", "uniprot_id": "UBC9_HUMAN", "id": "P63279-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63281-1", "uniprot_id": "UBC9_RAT", "id": "P63281-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63280-1", "uniprot_id": "UBC9_MOUSE", "id": "P63280-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DDJ0-1", "uniprot_id": "UBC9B_DANRE", "id": "Q9DDJ0-1", "name": "SUMO-conjugating enzyme UBC9-B", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFSP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W6H5-1", "uniprot_id": "UBC9A_DANRE", "id": "Q9W6H5-1", "name": "SUMO-conjugating enzyme UBC9-A", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPMKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFSPS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KNM2-1", "uniprot_id": "Q7KNM2_DROME", "id": "Q7KNM2-1", "name": "", "aln": "MSGIAITRLGEERKAWRKDHPFGFVARPAKNPDGTLNLMIWECAIPGKKSTPWEGGLYKLRMIFKDDYPTSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAITIKQILLGIQDLLNEPNIKDPAQAEAYTIYCQNRLEYEKRVRAQARAMAATE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50623-1", "uniprot_id": "UBC9_YEAST", "id": "P50623-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSSLCLQRLQEERKKWRKDHPFGFYAKPVKKADGSMDLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQDWRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:.: ** :*** ********* * * *:.**:::* **..****:.* * **:: : : : ::**:.*** ** . ::*********:***:*:*::*******:***:**:*:**:.** :.*** *: :.:*: **:*:* **: : ", "identical_positions": 81, "similar_positions": 48, "identity": "50.94%" }, { "cls_id": "homologset.agr.FB:FBgn0010612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPQ8-1", "uniprot_id": "ATP5L_MOUSE", "id": "Q9CPQ8-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFIRNFAEKAPSMVAAAVTYSKP-RLATFWHYAKVELVPPTPAEIPTAIQSVKK------IIQSAKTGSFKHLTVKEAVLNGLVATEVWMWFYIGEIIGKRGIVGYDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "J3QNM7-1", "uniprot_id": "J3QNM7_MOUSE", "id": "J3QNM7-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFIHNFSEKALSMVAAAVTYLKP-QLVTFWHYAKVELVPPTPGEIPTAIQNVKK------IIQSAKTGSFKHLTVKEAVLNGLVATEVLMWFYIGEIMGKRGIVGYDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAI9-1", "uniprot_id": "A0A8I6AAI9_RAT", "id": "A0A8I6AAI9-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFICNFVEKAPSVMAAAVTYLKP-RLATFLHYAKVELVPPTPGEIPTAIQSMKK------IIQSAKTCGFQHLTVKEAVLNGSVATEVWMWFYIREIIGKRGIVGYDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDU7-1", "uniprot_id": "ATP5L_RAT", "id": "Q6PDU7-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAKFIRNLADKAPSMVAAAVTYSKP-RLATFWHYARVELVPPTLGEIPTAIQSMKS------IIHSAQTGNFKHLTVKEAVLNGLVATEVWMWFYIGEIIGKRGIVGYDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75964-1", "uniprot_id": "ATP5L_HUMAN", "id": "O75964-1", "name": "ATP synthase F(0) complex subunit g, mitochondrial", "aln": "----MAQFVRNLVEKTPALVNAAVTYSKP-RLATFWYYAKVELVPPTPAEIPRAIQSLKK------IVNSAQTGSFKQLTVKEAVLNGLVATEVLMWFYVGEIIGKRGIIGYDV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7Z4Y8-1", "uniprot_id": "AT5L2_HUMAN", "id": "Q7Z4Y8-1", "name": "ATP synthase subunit g 2, mitochondrial", "aln": "----MAPFVRNLVEKTPALVNAAVTYLKP-RLAAFWYYTTVELVPPTPAEIPRAIQSLKK------IVSSAQTGSFKQLTVKEALLNGLVATEVSTWFYVREITGKRGIIG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKM3-1", "uniprot_id": "Q9VKM3_DROME", "id": "Q9VKM3-1", "name": "ATP synthase subunit g", "aln": "--------MASLATKGSGLVNRLLTQARP-QLDVFLKYAKVELTPPTPADIPAIRQGLGN------IIKGAKTGAYKNLTVREAWLNTLVTAEVIFWFYIGECIGKRHIVGYNV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12233-1", "uniprot_id": "ATPN_YEAST", "id": "Q12233-1", "name": "ATP synthase subunit g, mitochondrial", "aln": "MLSRIQNYTSGLVSKANLLSSKALYYGKVGAEISKQIYLKEGLQPPTVAQFKSVYSNLYKQSLNFALKPTEVLSCLKNIQKNELLKYGAYGIQLIGFYSVGEIIGRRKLVGYKHH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * : : : * * *** .:: ..: . : ::: .* :: :: : * *:* ::* ", "identical_positions": 11, "similar_positions": 25, "identity": "9.57%" }, { "cls_id": "homologset.agr.FB:FBgn0010622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUS4-1", "uniprot_id": "A0ABK0LUS4_RAT", "id": "A0ABK0LUS4-1", "name": "", "aln": "MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEVLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNTLVPVLDSASIKAVP-EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQLVQWDELLCQLEAAKQVKPAAE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0Y1-1", "uniprot_id": "DCTN3_MOUSE", "id": "Q9Z0Y1-1", "name": "Dynactin subunit 3", "aln": "MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNALVPVLDSASIKAVP-EHAARLQRLAQIHIQQQDQCVAITEESKALLEGYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75935-1", "uniprot_id": "DCTN3_HUMAN", "id": "O75935-1", "name": "Dynactin subunit 3", "aln": "MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP-EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQVKPAEE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1V8-1", "uniprot_id": "Q9W1V8_DROME", "id": "Q9W1V8-1", "name": "", "aln": "---MEALDILEKRIDALTRVLGPVQDSEVGEGVVDALCSAHAILGEATTGSAALQQCVKRSDELEKYLDPNFLEEHQQVRS-KEVYLQAVAPELHTQAEQLERIKQLEPALGAEYFRSIPAECLEQLKGITQNNGEYAQQSELIEESLVLAMKRYGEIQAGLLSSLDAMSERLDQVEERMEQRKRAELSKDVPPKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: *: *:: * * : .:. .. *.*.* ..:. **: :: :: *: : * *****::::. : * :: * : :*. **::: * * *.: ::::* * :*: ::* : : :*. * *. :: *.: * ..: .* * *:* : : * ", "identical_positions": 38, "similar_positions": 65, "identity": "19.39%" }, { "cls_id": "homologset.agr.FB:FBgn0010660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACK1-1", "uniprot_id": "D4ACK1_RAT", "id": "D4ACK1-1", "name": "Nuclear pore complex protein Nup214", "aln": "MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSVLTVSNKYGMLFAGGTNG--LNVFPTKSLLIQNKPGDDPNKIVDTIQGLNVPMKFPVHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNQAKPLKRPFTYHKLSNGASGMVNDMKWNPTVPSMAAVCLADGSISVLQVTDVVKVCAT-LPPSSGVTCVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYEADHPVRVLDVLWIGTYVFTIVYAGADGALETCPDVVMALLPKKEEKHPEIFVNFMEPCYSSCTERQHHYYLSYIEEWDLVLAASAASTEVSILAR--QSDQTNWESWVLEDSSRAELPVTDKSDDSLPVGVAIDYTNEVEVAINEEKTLPPAPVLLLLSTDGVLCPFYMINQNPGVRSLIKTLELISAEGERQPKSSGSFPSTPPSPQAPQNLDAPATAS-SPLPPVS-AAPTATFPLPSAGGGPSVFSFGPSPFKS-SSIPGEPPPYPTGSDSSRAAPASGTPTFSFAPPSKGTLAPTPAVAPVPTSAAPFTFGSSGFKPPLESTPMS--SAPNTGMKPSFPPSTSSVKVNLNEKFTAVASSAPVHSSTSIPSVLPFSSSPKPPASGPLSHPTPLPASPSSMPLKPSVSPSPSVGRSAQTAPSSAPSTGQKSPRVNPPVPKSGSSQARALQPPVTEKQRHQWKESDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTPEEMKMLRTESDDLHTFLFEIREATESLHGDISTLKTTLLEGFAGVEEAREQHGRNHDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQKKR--QRRLIVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYNQTSPWNRPSTLSTQSDTPSFD-----SDLE----HLLKTTIESHTKPSPRVPGKLSPAKQAQLRNFLAKRKTPPVRSTAPVSSDSQSRPCPSSLAVKAPLSTEHLIHFCSSCFRLRCKIMKMLSELLVSVSPSAEMARLSGLLRVSNVVFGRAFVASLSRSAFLSQRYYEDLDEGSSASSVAHPLEGEDARPT--------------PTCREEEAVVPVPRHAPVVRTPSVQPSLLPQAMPFAKPHLIHSSSPAAMSSSISTSATKVIPQGADTTMLATKTVKHGAPGPSHTVAAPQAAAAAALRRQMASQAPAVSTLTESTLKNVPQVVNVQELKSNPSPPSAAMGSSGPHSAAKAPHAVLTPVAASQAKQGSLINSFKPSGPTPVSCQLSSGDKAVGPGTAKTESPVTSTPSTG-QLNKPFSFASPGT-FTFGTITPAPSSSFTATPGAAPPTKESNQLEAFSFGGGGKPFCETIPGNPPATGPPSAPSTSVTTTSLEDSAPTSSKPATP-ETPVSTASSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQAEESTKPVSKASSTNLAGAQPAK----PSGFSFPAASVLGKPVEPSVTS---SAPAAPVSALSASTSSSSATVFGSVPLTSAAPSGLMSFSGASLASSKASFSFGNQQTSSAAAAAATPASTSVAPSLPASFPTLSFGGLLSSPSASSLPVSSGKITEEATPPAVPDKSDHSEVSASTPSLPLQPPSAQLPQASLQTSDPVKKEPVPAQTTDS---RPSSSASLVAS-TESTPVAPGGPDSKTEAVSPASTFAGPG-PAVVAAVLLGAGSAASEASGTPSTSSTVSSSTPTPATETAVFGTATSGSSVFTQPPAASSSSAFNQLSSNTATAPSATPVFGQVAAS------------IASTAAATPQASSSGFGSPAFGASAPGVFGQTAFGQSPAFGQATSSPASGFSFSQPGFSSVPAFGQSVSSTPTSTSANVFGATSSTSSPGSFSFGQASTNTGGTLFGQNNPP-AFGQSPGFGQ-GGSVFGSTSATTSTAAPSGFSFCQASGFGSSNTGSVFGQAASSGGSVFGQQSSTSSGSVFGSGNATRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTPTPNTSNLFGNSGAKTFGGFG-SSFGEQKPAGTFSSGGGSVASQGFGFSTPNKTGGFGAAP-VFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTASFGTLASQNAPTFGSLSQQTSGFGTPSSGFSGFGSGTGAFTFGSSNSSVQGFGGWRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U93-1", "uniprot_id": "NU214_MOUSE", "id": "Q80U93-1", "name": "Nuclear pore complex protein Nup214", "aln": "MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSVLTISNKYGMLFAGGTNG--LNVFPTKSLLIQNKPGDDPNKIVDTIQGLNVPMKFPVHHLALSCDSLTLSACMMSSEYGSIIAFFDVRTFSNQAKPLKRPFTYHKVSNDASGMVNDMKWNPTVPSMVAVCLADGSISVLQVTDVVKVCAT-LPPSTGVTCVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFTIVYAGADGTLETCPDVVMALLPKKEEKHPEIFVNFMEPCYSSCTERQHHYYLSYIEEWDLVLAASAASTEVSILAR--QNDQTNWESWLLEDSSRAELPVTDKSDDSLPMGVAIDYTNEVEVTINEEKTLPPAPVLLLLSTDGVLCPFYMINQNPGVRSLIKTLELISTEGERQPKSSGSFPGTPSSPQAPQNLDAPATAS-SPLPPVS-AAPTSTFPMPSAAGSPSVFSFGPSSFKSSASVTGEPPLYPTGSDSSRAAPGSGTSTFSFAPPSKGSLASTPAVAPVATSAAPFTFG---FKPTLESTPMS--STPNTGMKPSFPPSASSVKVNLNEKFTAVASSAPVHSSTSTPSVLPFSSSPKPTASGPLSHPTPLPASSSSMPLKSSVSPSPAAGRSTQTAPSSAPSTGQKSPRVNPPVPKSGSSQAKALQPPVTEKQRPQWKDSDPVLAGIGEEIAHFQKELEELKARTAKACLQVGTSEEMKMLRTESDDLHTFLFEIRETTESLHGDISTLKTTLLEGFAGVEEAREQHGRNHDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQKKR--QRRLIVPERETLFNTLANNREIINQQRKRLNQLVDSLQQLRLYNHTAPWSLPSALSTQSNSHSFD-----SDLE----CLLKTTIESHTKPSPRVPGKLSPAKQAQLRNFLAKRKTPPVRSTAPAS---------------------------------------------------------------------------LSRSAFLSQRYYEDLDEGSSASSVAQPLEGEDARPTCTSVAQPLEGEDAQPICKEEEAVVPVPRHAPVVRTPSIQPSLLPQSMPFAKPHLIHSSSPAVMSSAVSTSATKVIPQGADSTMLATKTVKHGAPGPSHTVAAPQAAAAAALRRQMASQAPAMSTLTESTLKTVPQVVNVQELRSNPSPPSAAMGSAVQHSAAKTPHAVLTPVANSQAKQGSLINSFKPSGPTAASCQLSSGDKAVGQGTAKTESAATSTPSAAGQLNKPFSFASPGT-FTFGTITPTPSSSFTATPGAGPPTKEPTQLEAFSFGGGGKPFSEAIPGNSPATGATSAPSTSVTAASLEDSAPSSSKPAAPPETTVSSASSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQAEDSTKPVSKASSTNLAGAQPAK----PSGVSFPNTSVLGKPVEPAVTSSVSPAPAAPASALNVSTSSSSATVFGSVPLTSAGPPGLISFGGAALASSKASFSFGNQQTSSSTASSATPTSTSVAPSLPASFPTLSFGGLLSSPSASSLPVSSGKSTEEAAPPAVPDKSDSSEVSATTPSLPVQP---QSTQASLQTSDPVKKEPVLVQTTDSSPSRPASSASFVAS-TESMPVTLGAPDSKIEAVSPASTFAGPGQAAVATAVLPGAGSAATEASGTP-TTSTVSSSSPTSATETAVFGTATSGSSVFTQPPAASSSSAFSQLSSNTATAPSATPVFGQVAAS------------ITSTAAATPQASSSGFGSPAFGASAPGVFGQTAFGQTPAFGQATSSPASGFSFSQPGFSSVPAFGQSVSSTPASTSANVFGATSSTSSPGSFSFGQASTNTGGTLFGQNNPP-AFGQSPGFGQ-GSSVFGGTSATTSTAAPSGFSFCQASGFGSSNTGSVFGQAANTGGSVFGQ-SSTSSGGVFGSGNATRGGGFFSGLGGKPSQDAANKNPFSSAGGGFGSTAAPNTSNLFGNSGAKTFGGFGSSSFGEQKPAGTFSSGGGSVASQGFGFSTPNKTGGFGAAP-VFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSGNTASFGTLASQNAPTFGSLSQQTSGFGTPSSGFAGFGSGTGAFTFGSSNSSVQGFGGWRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35658-1", "uniprot_id": "NU214_HUMAN", "id": "P35658-1", "name": "Nuclear pore complex protein Nup214", "aln": "MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASG--LQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCAT-LPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILAR--QSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSP-SGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKK--QRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFD-----SDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPAS---------------------------------------------------------------------------LSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTS----------------CKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKAS--GTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTP-----GEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTS----SATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATP-LPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAP-AFGQSPGFGQ-GGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAP-VFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1X4-1", "uniprot_id": "NU214_DROME", "id": "Q9W1X4-1", "name": "Nuclear pore complex protein Nup214", "aln": "---MAQNAPDCEDTQDFQFKLHHKIVAFKKCG-EPRSNVNLLAVSSSRGLLFAGSPTQPELKVIIVKDLVNAKSTAQQP-------QARLVPLPSIPNYIACSSD-GNLLAVNHTQNGTSLLSIYAVLSFMTPD---VRPVYNIRLAAEDHVHGVQLLWNPVLPNSLAVVLSNGALAMYALKEGGNFEMHSLDKNQQVKCGCWSPKGKQIVLGFPGGTVKQFKPDLTLAKTLLCPPN-IHDAPFDTIAIQWLSTFQFAVIFLQHG--EDCSPSLYILNAPKAG---APSYINYYDICYSMNGPRNHQFVFSHVPQWNLLLVVSANGVEVGIMRSTEAGDTPAWQQLTLLDEARIEMPLSEDKDETFPLGFAFDTSTTHQLTIN-EKKLQTMPMVHVLSSDGELLSFNFLN-------VLPTAVSVCSPPPPVADTSGQFKPLNMLLASEEEEQPAWAASPSKAPAAT-----------PAASSDISFAFTPNTVTSTPAPSKDKQPSLFSGFGAAAAKAPAP-QLSFG---------------TAPTSSPVSFGAPTTNAAKPTTPFG-----GFGTQATTTAMGSMFSASGANAFGGMALNKPAIASVTPRTAAPGSTVPATPASAPANKP-------------------------LYTVPLTFTPVDTKPATSAPPQIADESLKPDDTEPIIKD--------------MIALQIEAFSKDIQKQKEQTKELLKGIAAPSALRAYAKRLDDLQELNEQAKDVEFELD--VQGLRQGLNEAYAIVAECRGKLEIYRKPEITRLMNSSSCDPSGRRMLARLQSYVAANEAQLRLAQQHVDLQWEQFQDVVRRNSKSRMHMPCLEGIYQRLTRLQNLTSNQRIVQNNIKSKLKERGLLQAALLDQEKSRTRTNEAVDTLTDSILT---------------MSLSQVVDSNAAKLTRERLQKIRNIVQLQKINVICPQRPDRVG------------------------------------------------------------------------LKSEVILETKRRAEQIKRAAAKPATANKYTQAAVAPP------------------SPPDVAPTPAVAPMPQATVTVAPPLPKPMPSIPSVVEKPGVPTHPTTPVATPFSFSQSIPFVKTSTVTPTTNTVTPG--------------------EAAKPGLSIFGGSTIS-------SFSFGGGAAKSALSFGTGSPAVAAPTPKPNPLSAVEKPTP--------EPTKPKEQKAAESKEFKAVQPETEESKVPQKPKAETE---NKSFGFG-----------------GFTGTGGTVGNTSSS----PFSFGGLG-----------------------------SSLGFGGTAAAVPKSEPSSTATTSVATSASTAPFGIFSAALAKPSN--------------SEPITTVTSN--------------------TTTITSKPTNVIASSSVTDAPSVTTTNAVTSSTDPIGGLFSSVTICKPN---------TPADTTKPANIFGGGLSAG----------------------SFSFGGTIDASKG----LFGSTKPVATAPTSVTEANNKTDPISTTP-----------------------------------------SAISTTTATTTVSSPAVVPAAVTAAVPATSSTTVTSSTAVPGSAFSFSNAFSTLSAGGAAAPTTSASAPLAAKSPTATSTGNNSSNSVFGGGFAVATS----------TAAPVASPFQSAAKSP----------------------------------VSSANIFGSIPKAETSVFGGATTAPSN----------------TTAAATPDAPPAGLFASAAISNPSPFGSPTTRAPASGGNIFGQAVKPSVFGQPAQAGDSGGSIFGGGSASTP--------FGSSSIFGGGNTQGAVGAPAAGSTSIFGQKVFGQSS----AAAPAAGGNIFSNPVGSPQASPFGGGGNSIFGSPATAPPASGGSIFGGGSSSGGFGSFTQTTPAQGGFGGGFGQGGGGSVAQ-TGFGSPQAPQQQTTTPGGFGAKPVFGGSPAFGASPTFGGGATFGSPKGFGG---FGGASPVASPPPFGAAAKP----------AQGNIFETLGGQESGLSFGNLAQTGN-SNAQKPAFGGSS-----FMNYR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :****: :*: *.. *:.. .:*::*.. *::***... *::: .*.*: :...::* *. **: :::* *.* .* * :.: *::::: * :* . **. :: :: ***.:*. ** *::*:::: :.: :. * . *.. ********:.:* .*** *: * * *.: *** * *. .: : *:.*: *:::: . : .*.: : ** . ::*: : **. *:*:: :*:: :*:*:*..** ..**.*: .* *:. * *.:* *:*:::..*:::*:*...* :. :::*. **.* . *:: :**:** * .* ::* :: * :. ..:.*. : :: :.. :*: : *. : .*... *:* .....* .: . : .. .: ** .... :** ...:::..:** :.. :**. . . :.: .. * .... : * . * . *. :* : . * *: . ..**.* .:* . . .. *.. ** * :. :* : : *. :* *.*:::: * :* : :.:.. :: .. ***: : : ::. .*. :. *: * *.:* * *.* : :.. :*: . . **... * .:: : :: .:: :**:*::. : :: : :: :* * ::: *:. ::: .:** *:: ..*:: * : : . * ::. :: * :: ..**: : ::**:: :* : . * *. : ::* *::.. :: .:.:: . .. . *. .* **: ::. .. **:. * . : : . * :.::*. : . .* .* *.: :*. : *.:. : **:. .: ...: .: ::*:. :* :*:. ... . : :*: *. . *. ** * : : . .....: .*.*.*. .**.: *: *... .** ** . . . .: ...* . *::::.: *..*. :*.::** : ::* ...:*. ..: .* .: .:* :.:.. .::: . :*.*:.: .. :. : *.: **. : . ::***. :.:.. : .. . ::..::.: . :: :::. *: .: : : . . * : **..:*: : .. .** :.: :.. : ::. . :.:* : . . : :*. .*..*** *.::* ::** *:*. . . :. .::..:**. . .::..** ::::.:. ..::** :....:*.::: :... * :. :** :*** * .***.. *: *.*:**. **:*. * .:* **..** ...* .* . :*** .*. :. . **.:**. *.*. .. . . * .. :..:.. * : *.*.: **.* :: .: * *..***. .:* **.:*: . ::* **: *.*****.**. *:**...:* ** * * ** .:..**. ** .:. :. * :*. * **:. . . :* *.: :**... * .:* ", "identical_positions": 348, "similar_positions": 723, "identity": "15.75%" }, { "cls_id": "homologset.agr.FB:FBgn0010741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN18-1", "uniprot_id": "PFD2_RAT", "id": "B0BN18-1", "name": "Prefoldin subunit 2", "aln": "MADSSGRVGKSGGSGTGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALEGNKEQIQKIIETLSQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKSSSAGVLVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70591-1", "uniprot_id": "PFD2_MOUSE", "id": "O70591-1", "name": "Prefoldin subunit 2", "aln": "MADSSGRVGKSGGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALEGNKEQIQKIIETLSQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHV9-1", "uniprot_id": "PFD2_HUMAN", "id": "Q9UHV9-1", "name": "Prefoldin subunit 2", "aln": "MAENSGRAGKSSGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALENNKEQIQKIIETLTQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTE5-1", "uniprot_id": "PFD2_DROME", "id": "Q9VTE5-1", "name": "Probable prefoldin subunit 2", "aln": "MSTES-----------AKPALSQEAIVAQFQQLRNEQRNLVNSLNTLEMDLREHKTVIETLEAADPERKCFRQIGGVLCERTVKEVLPQLVENKDFIAKTIQMVTNDLSKKGSELNKFKEEHNIKIRGEH-LVAEGAKGDDAEDKAENRNVLVFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40005-1", "uniprot_id": "PFD2_YEAST", "id": "P40005-1", "name": "Prefoldin subunit 2", "aln": "------------------MEQRNNVFQAKYNEYKQILEELQTKIIELGHDKDEHTIVIKTLKDAEPTRKCYRMIGGALVESDVQTSLPILETKKENIEGTISKMKETLIQTAKEFEKWKKDNKIQVVKN--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * ::. :: . * .. * : **. **.**: .: ***:* :**.* * *: ** * :*: * *. :.: * ...*::::::.::*:: : ", "identical_positions": 27, "similar_positions": 41, "identity": "17.42%" }, { "cls_id": "homologset.agr.FB:FBgn0010747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61011-1", "uniprot_id": "SRP54_HUMAN", "id": "P61011-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14576-1", "uniprot_id": "SRP54_MOUSE", "id": "P14576-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYB5-1", "uniprot_id": "SRP54_RAT", "id": "Q6AYB5-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYFYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PXC0-1", "uniprot_id": "E9PXC0_MOUSE", "id": "E9PXC0-1", "name": "Signal recognition particle 54 kDa protein", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMAS----GLNKRKMIQHAVFKELVKLVDPG---VKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNKALIEKWKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKHPGRIQRVARGSGVSTRDIQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVN5-1", "uniprot_id": "SRP54_DANRE", "id": "Q7ZVN5-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGRKITSALR-SLSNATIINEEVLNAMLKEVCAALLEADVNIKLVKQLRENVKAAIDLEEMAS----GLNKRRMIQHAVFKELVKLVDPG---VKAWTPTKGKNNVIMFVGLQGSGKTTTCSKLAYYFQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIAAEGVEKFKSENFEIIIVDTSGRHKQEDSLFEEMLQVSNAVQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELK-LDDNEELIDKLKHGQFTLRDMYEQFQNIMKMGPFGQIMGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDNKDGAKLFSKQPNRIQRVARGSGVATRDVQELLTQYTKFAQMVK--------------KMGGIKGLFKGGDMSKNVNPSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKG----MMGFNNM-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3D9-1", "uniprot_id": "Q9V3D9_DROME", "id": "Q9V3D9-1", "name": "Signal recognition particle 54 kDa protein", "aln": "MVLADLGRKITTALH-SLSKATVINEEALNSMLKEICAALLEADVNIRLVKQLRENVRAVIDFDEMAG----GLNKRRMIQSAVFKELVKLVDPG---VKPYQPIKGKANVVMFVGLQGSGKTTTCTKLAYHYQKRNWKSCLVCADTFRAGAYDQVKQNATKARIPFYGSYTEIDPVVIAQDGVDMFKREGFEMIIVDTSGRHKQEESLFEEMLAVSNAVSPDNIIFVMDATIGQACEAQAKAFKDKVDIGSVIITKLDGHAKGGGALSAVAATQSPIIFIGTGEHIDDLEPFKTKPFVSKLLGMGDIEGLIDKVNELK-LDGNDELLEKIKHGHFTIRDMYEQFQNIMKMGPFSQFMNMIPGFSQDFMTKGGEQESMARVKRMMTMMDSMSDNELDNRDGAKLFSKQPNRCVRVAQGAGVMEREVKELIAHYTKFSAVVK--------------KMGGVKGLFKQGDMTKNVNPTQMAKLNQQIAKMIDPRMLQQMGGVGGIQNMMRQLQQGAAGGLGGLGNLMSGFGGK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20424-1", "uniprot_id": "SRP54_YEAST", "id": "P20424-1", "name": "Signal recognition particle subunit SRP54", "aln": "MVLADLGKRINSAVNNAISNTQDDFTTSVDVMLKGIVTALLESDVNIALVSKLRNNIRSQLLSENRSEKSTTNAQTKKLIQKTVFDELCKLVTCEGSEEKAFVPKKRKTNIIMFVGLQGSGKTTSCTKLAVYYSKRGFKVGLVCADTFRAGAFDQLKQNAIRARIPFYGSYTETDPAKVAEEGINKFKKEKFDIIIVDTSGRHHQEEELFQEMIEISNVIKPNQTIMVLDASIGQAAEQQSKAFKESSDFGAIILTKMDGHARGGGAISAVAATNTPIIFIGTGEHIHDLEKFSPKSFISKLLGIGDIESLFEQLQTVSNKEDAKATMENIQKGKFTLLDFKKQMQTIMKMGPLSNIAQMIPGMS-NMMNQVGEEETSQKMKKMVYVLDSMTKEELES--DGRMFIEEPTRMVRVAKGSGTSVFEVEMILMQQQMMARMAQTATQQQPGAPGANARMPGMPNMPGMPNMPGMPNMPGMPKVTPQMMQQAQQKLKQNPG---LMQNMMNMFGGGMGGGMGG---GMPDMNEMMKMMQDPQMQQMAKQFGMG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******::*.:*:. ::*:: :: *** : :****:**** **.:**:*::: : :: : . :.:::** :**.** *** *.: * * * *::************:*:*** .:.::.:* *:*********:**:**** :*********** **. :* :*:: ** * *::*********:**:.**:**: ::*.:.*:: : *:**:****.* *:****:. *..::*:**:****:****:******::***********.*:* *..:.*:*****:****.*::::: :. :. . ::: ::*:**: *: :*:*.******:.:: ****:. ::*.: .*:*: ::*::: ::***..:**:. ..::* :.* * ***:*:*. ::: :: : :: :.: :* *: .: :*. . . *.*:. *: : : :: :: * :*.**. : * .*.: * * .:. ", "identical_positions": 212, "similar_positions": 189, "identity": "38.55%" }, { "cls_id": "homologset.agr.FB:FBgn0010750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N7H5-1", "uniprot_id": "PAF1_HUMAN", "id": "Q8N7H5-1", "name": "RNA polymerase II-associated factor 1 homolog", "aln": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYP----FDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPD--TYRIDPNVLLDPADEKLLEEE---IQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISN-EKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYD---YKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEE-EMETEEKEAGGSDEEQ---EKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARA-ARDKE-EIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSR----SASPFPSGSEHSAQEDGSEAAASDS-SEADSDSD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2T8-1", "uniprot_id": "PAF1_MOUSE", "id": "Q8K2T8-1", "name": "RNA polymerase II-associated factor 1 homolog", "aln": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYP----FDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPD--TYRIDPNVLLDPADEKLLEEE---IQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISN-EKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYD---YKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEE-EMEAEEKEAGGSDEEQ---EKGSSSEKEGSEDEHSGSESDREEGDRDEASDKSGSGEDESSEDEARA-ARDKE-EIFGSDADSEDDADSDDEDRGQAHRGSDNDSDSGSDGGGQRSRSQSRSRSRSASPFPSGSEHSAQEDGSEAAASDS-SEADSDSD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V886-1", "uniprot_id": "PAF1_RAT", "id": "Q4V886-1", "name": "RNA polymerase II-associated factor 1 homolog", "aln": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYP----FDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPD--TYRIDPNVLLDPADEKLLEEE---IQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISN-EKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYD---YKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEE-EMEAEEKEAGGSDEEH---EKGSSSEKEGSEDERSGSESDREEGDRDEASDKSGSGEDESSEDEARA-ARDKE-EIFGSDADSEDDADSDDEDRGQAHRGSDNDSDSGSDGGGQRSRSQSRSRSRSASPFPSGSEHSAQEDGSEAAASDS-SEADSDSD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4U0S5-1", "uniprot_id": "PAF1_DANRE", "id": "Q4U0S5-1", "name": "RNA polymerase II-associated factor 1 homolog", "aln": "MAPTIQTQAQREDGHRSSAHRTVPERSGVVCRVKYGNSLPDIPFDPKFITYP----FDQHRFVQYKATSLEKQHKHELLTEPDLGVTIDLINPD--TYRIDPNILLDPADEKLLEEE---IQAPSSSKRSQQHAKVVPWMRKTEYISTEFNRYGVSN-EKVEVKIGVSVKQQFTEEEIYKDRDSQIAAIEKTFEDAQKSISQHYSKPRVTPVEVLPVFPDFKMWINPCAQVIFDSDPAPKDVSAPAGVDMMSQAMIRGMMDEEGNQFVAYFLPNEDTMRKRKRDVEEELDYMPEEVYE---YKIAREYNWNVKNKASKGYEENYFFIFRDADGVYYNELETRVRLSKRRAKVGAQSSTNAVLVCKHRDMNEKELEAQEARKAQLENHEPEDEEEELDLEKDMQEDSGEEREKPSDSENSESESEREEEERPADEDEEEEEDEESVKRRRERKSSGSESGDDRQ-ARDEE-EIFGSDDDSEEEEEEEEE-------------------GGARRRSNSS-----------SVQHSASER-----ASDS-SDA-SDSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN55-1", "uniprot_id": "Q9VN55_DROME", "id": "Q9VN55-1", "name": "RNA polymerase II-associated factor 1 homolog", "aln": "MPPTINNSAVNSAAEK-RPQRQTERKSEIICRVKYGNNLPDIPFDLKFLQYP----FDSHRFVQYNPTSLERNFKYDVLTEHDLGVTVDLINRE--LYQADSMTLLDPADEKLLEEE---TLTPTDSVRSRQHSRTVSWLRKSEYISTEQTRFQPQNLENIEAKVGYNVKKSLREETLYLDREAQIKAIEKTFSDTKSEITKHYSKPNVVPVEVLPIFPDFTNWKFPCAQVIFDSDPAPAGKNVPAQLEEMSQAMIRGVMDESGEQFVAYFLPTEQTLEKRRTDFINGELYKEEEEYE---YKIAREYNWNVKTKASKGYEENYFFVMRQ-DGIYYNELETRVRLNKRRVKVGQQP-NNTKLVVKHRPLDSMEHRMQRYRERQLEVPGEEEEIVEEVREEEQMQIIGETEKT---SEDAAVGAQAASGADSPAQVARDRQSRSRSRTRSGSSSGSGSGSGSRASSRSKSGSRSGSGSRSRTNSPAGSQKSGSRSRSVSRSRSRSKSGSRSRSRSRSKSGSRSRSGSRSGSGSRSPSRSRSGSPSGSGSSSGSASDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38351-1", "uniprot_id": "PAF1_YEAST", "id": "P38351-1", "name": "RNA polymerase II-associated protein 1", "aln": "----------------------MSKKQEYIAPIKYQNSLPVPQLPPKLLVYPESPETNADSSQLINSLYIKTNVTNLIQQDEDLGMPVDLMKFPGLLNKLDSKLLYGFDNVKLDKDDRILLRDPRIDRLTKTDISKVTFLRRTEYVSNTIAAHDNTS-----LKRKRRLDDGDSDDEN-LDVNHIISRVEGTFN--KTDKWQHPVKKGVKMVKKWDLLPDTASMDQVYFILKFMGSASLDTK----EKKSLNTGIFRPVELEE-DEWISMYATDHKDSAILENELEKGMDEMDDDSHEGKIYKFKRIRDYDMKQVAEKPMTELAIRLNDKDGIAYYKPLRSKIELRRRRVNDIIKP------LVKEHDIDQLNVTLRNPSTKEANIRDKLRMKFDPINFATVDEEDDEDEEQ---PEDVKKESEGDSKTEGSEQEGENEKDEEIKQEKENEQDEENKQDENRAADTPETSDAVHTEQKPEEEKETLQEE-------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. :. :** *.** : *:: ** : . :. :: : . : : ***:.:**:: : *. * . : ** ::: * . :: . *.::*::**:*. . . * :.. :: * : * :* **. :.. :* * * *: ::** : * ...: . :. .::* : *. ::::: : . .. . : : :: :: **: * ::::* *.* * : : . . **: *.:::.* :**.: :. : *.: ::. : :. : : : : .. .: :. : . : .:. ... : . .. . * : . : .. : .: ", "identical_positions": 53, "similar_positions": 151, "identity": "9.53%" }, { "cls_id": "homologset.agr.FB:FBgn0010762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZR6-1", "uniprot_id": "A0A0G2JZR6_RAT", "id": "A0A0G2JZR6-1", "name": "", "aln": "MWDNRMDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSG---------------------VKSYEEKLNGNLRPHGDN-RTAGRPGKENINDEPVDMSARRSEPDRGRLTPSPDIIVLSDNE-ASSPRSSSRMEERLKAAN----LEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQ-LQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNLRTLQG----------HSVIR--SAANTTLPHMLMSQRVIAP-----NPAQLQGQRGPPKPGIVRTTTPNMNPAISYQPQSSSSVPCQR--TTSSAIYMNLASHIQPG------------------TVNR---VS-------SPLPSPS---AMSDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQG-----KNCASLLRVEPFVCAQCRTDFTPHWKQE----KNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQ-------------------------------------------------------------------------AALSPTTAPAVSS---VSKQET----------------------------------------------------IMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGM------------------------------------------------------------------------------------------------------------------------------------PGVNIAYLNTG-IGGHKAPSLADRQREYLLDMIPPRSISQSISGQK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHR5-1", "uniprot_id": "P66B_MOUSE", "id": "Q8VHR5-1", "name": "Transcriptional repressor p66-beta", "aln": "-----MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSG---------------------VKGYEEKLNGNLRPHGDNNRTAGRPGKENINDEPVDMSARRSEPDRGRLTPSPDIIVLSDNE-ASSPRSSSRMEERLKAAN----LEMFKGKGMEERQQLIKQLRDELRLEEARLVLLKKLRQSQ-LQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGIEPQNMRTLQG----------HSVIR--SATNTTLPHMLMSQRVIAP-----NPAQLQGQRGPPKPGIVRTTTPNMNPAISYQPQSSSSVPCQR--TTSSAIYMNLASHIQPG------------------TVNR---VS-------SPLPSPS---AMSDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQG-----KNCASLLRVEPFVCAQCRTDFTPHWKQE----KNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQ-------------------------------------------------------------------------AALSPTTAPAVSS---VSKQET----------------------------------------------------IMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGM------------------------------------------------------------------------------------------------------------------------------------PGVNIAYLNTG-IGGHKAPSLADRQREYLLDMIPPRSISQSISGQK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXI9-1", "uniprot_id": "P66B_HUMAN", "id": "Q8WXI9-1", "name": "Transcriptional repressor p66-beta", "aln": "-----MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSG---------------------VKGYEEKLNGNLRPHGDN-RTAGRPGKENINDEPVDMSARRSEPERGRLTPSPDIIVLSDNE-ASSPRSSSRMEERLKAAN----LEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQ-LQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQG----------HSVIR--SATNTTLPHMLMSQRVIAP-----NPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQR--TTSSAIYMNLASHIQPG------------------TVNR---VS-------SPLPSPS---AMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQG-----KSCASLLRVEPFVCAQCRTDFTPHWKQE----KNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQ-------------------------------------------------------------------------AALSPTTAPAVSS---VSKQET----------------------------------------------------IMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGM------------------------------------------------------------------------------------------------------------------------------------PGVNIAYLNTG-IGGHKGPSLADRQREYLLDMIPPRSISQSISGQK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N9R4-1", "uniprot_id": "A0A8M1N9R4_DANRE", "id": "A0A8M1N9R4-1", "name": "", "aln": "-----MERMSEEALRLNLLKRGLEAPDEREE--AKRLKMDGHEAMERLKMLALLKRKDLAALEGAAVAAAMAEGKGPCG------------SQGLMGAVAYEEKMNGSLRVGGHG--GPSKNGKENIVDEPVDMSARRSEMVRERRTPSPDVIILSDNE-ASSPRSTPHPEEKQHQAN----LEMFKGKTGEERQQMIKALREELRLEEAKLVLLKKLRQSQ-MQKENVVQKVPVVQNAPSSVQPSPMHS-SQGLGKLPVRPGMHSSEPQNLRTAQG----------HTVIR--SAANASLPPMMMSQRVIAP-----NPAQLQGQRLPSKPGMGRSSTGGLGNAVSYQQAASQQVGVSQRSGSSSAIYMNLAHMQAAG------------------AAGVGVGVSGVGAVSPSTLSSASSVASLNDQASSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQG-----KMRGSLPHVEPFFCAQCRTDFTPHWKQE----KSGRILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQQQ-------------------------------------------------------------------------AALSPSSGQTVPS---VSKGET----------------------------------------------------MIRHHALRQTPQPQAALQRGLSSSARGVLSNFAQASQLSVASGLLGMTSKRCGSSSSSGGGTSSSRPQ-----------------------------------------------------------------------------------------------------HDSRRQIYNIPGLNIAYLNPGAIGGHKASSLADRQREYLLDMIPPRSISQSITGQK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LDI1-1", "uniprot_id": "A0ABK0LDI1_RAT", "id": "A0ABK0LDI1-1", "name": "", "aln": "--------MSEEACRTRSQKRAFEPDLTEDDVESKKMKMERG--PSELPVDGDSR-----------VMPEPSAGPA-----------------------------QGLLRTTEA--MGTGS-GEGLLGDGPVDMRTSHSDMKSEKRPPSPDVIVLSDSEQPSSPRVNGLTTVALKDTS----TEALLKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQ-IQKEATAQK-PTASSGSTVTTPPPLVRGPQNIP--AGKPSLQTSSTRIPGSIIP----------PPLVRGGQQVSAKLGPQASSQVVMPPLVRGAQVSQIHNIRQHSSTGPPPLLLAPRASVPSMQIQGQRIIQQGLIRVANVPNTSLLVNIPQPT------------------AASLKGTTVGSAQANSTPSSVASVVASAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRISATSAAAVLSREPYMCVQCKTDFTCRWRE-----KGGAVMCENCMTSNQKKALKVEHTSRLKAAFVKALQQEQEMEQRLLQQGVGTASIKAET--------------------------------------------------------------AAPHPSLKQVIKPRRKLAFRSG----------------------------------------------------EARDWNNGSVLQTSSQLSRGSATTPRGVLHTFSQSPKLQNAASATALVSRTGRHSERVVGTSKGTAS--------------------------------------------------------------------------------------------------------NWKKTPLSTGGTLAFVSPS-LAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHY6-1", "uniprot_id": "P66A_MOUSE", "id": "Q8CHY6-1", "name": "Transcriptional repressor p66 alpha", "aln": "--------MSEEACRTRSQKRTLEPDLTEDDVENKKMKMEKG--SSELTVDGDSR-----------VMPEPSAGSA-----------------------------QGLLRTTEA--MGTGS-GEGLLGDGPVDMRTSHSDMKSEKRPPSPDVIVLSDSEQPSSPRVNGLTTVALKDTS----TEALLKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQ-IQKEATAQK-PTASSGSTVTTPPPLVRGTQNIP--AGKTSLQTSSTRIPGSIIP----------PPLVRGGQQVSAKLGPQASSQVVMPPLVRG---AQIHNIRQHSSTGPPPLLLAPRASVPSMQIQGQRIIQQGLIRVANVPNTSLLVNIPQPT------------------AASMKGTAVASAQANSTPTSVASVVASAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRISATAAAAVLSREPYMCVQCKTDFTCRWRE-----KGGAVMCENCMTSNQKKALKVEHTSRLKAAFVKALQQEQEMEQRLLQQGVGTASIKAEP--------------------------------------------------------------AAPHPTLKQVIKPRRKLAFRSG----------------------------------------------------EARVWNNGSSLQASSQLSRGSATAPRGVLHTFSQSPKLQNAASATALVSRTGRHSERVVGTGKGTAS--------------------------------------------------------------------------------------------------------NWKKTPLSTGGTLAFVSPS-LAVHKTSSAVDRQREYLLDMIPPRSIPQSATWK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YP4-1", "uniprot_id": "P66A_HUMAN", "id": "Q86YP4-1", "name": "Transcriptional repressor p66-alpha", "aln": "--------MTEEACRTRSQKRALERDPTEDDVESKKIKMERGLLASDLNTDGDMR-----------VTPEPGAGPT-----------------------------QGLLRATEATAMAMGR-GEGLVGDGPVDMRTSHSDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETS----TEALMKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQSQ-IQKEATAQK-PTGSVGSTVTTPPPLVRGTQNIP--AGKPSLQTSSARMPGSVIP----------PPLVRGGQQASSKLGPQASSQVVMPPLVRG--AQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPT------------------PASLKGTTATSAQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQG----RMSAATVLSREPYMCAQCKTDFTCRWREE----KSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPT-------------------------------------------------------------AAPHPVLKQVIKPRRKLAFRSG----------------------------------------------------EARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATS-------------------------------------------------------------------------------------------------------NWKKTPLSTGGTLAFVSPS-LAVHKSSSAVDRQREYLLDMIPPRSIPQSATWK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PF79-1", "uniprot_id": "M9PF79_DROME", "id": "M9PF79-1", "name": "", "aln": "-----MAKMEVDDVVDLSLGSGRDPALTITPAPPPAALSNRDLRALTANNAGLTITPSASPATNNGTTSNSSNTNSNSSSTTTTTNNNNNSSSNTNSSSANNNNNNNSINASDGVTGATSGSIGGGQDENKVQRRVLRPRTEPKSYAEAPDIVLLPARTNGRQQNGNIDSETDDEEMPPYVPIKELSHAELKEREKSLRKLRQDLRNEETKLMLLKKLKQSQQVMKENLVVTPTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAHSKGSRSSLSGSGGPAVSISATNSRTGSSSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSSSHRSSNLPPRTNLPNLTITPSVTITPTSAPPSSLKPRNVPGTISNSVSITPALPLSQSHQNQHNDQKNDRSTPREDAQTPAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIPNPSNTDFVYLLGLETVVDYLTVNKK---------ANAVAAPFRCAQCKIDFTPVWKWEKQTNKDPKVICEQCVTSNVKKALKAEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSSNSSSSHMQREREQLQASHASAAAALVNLPPSVTVIPTKCQTPTPATPRPTPPPPQSQATPPPSSGGSRSSRAAATAAAAAIAAQQAGILSPGPSPAHHHEPTTSSRSSRNDRLDHHHQSQQQQQRDQRERDQQQRDQQSQQQAQNYDKYSAATLAAAAHLSALGGMGGLNINSLASLGNLGNLGNLSQLGNLAALGGLGNFGGASTGSANPAAGLSGSSPAATAAAMQAFQQQLFRALGQGLGGNPQHMMQFAPLLYSYQMAMAQAAQVAGEMTMALTGKFITGYQECDSVTFNNNNKKSSSSSGSAKNSSSSNSMAEVQRAAELQRQYLLEMIPPQQQSGASGSRQNNWKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . . :. :. . : *: . :. . :**:::*. . . . . : : :**:: :: *:::** **::*:*****:*** : ** . . . . . .. .: . . .: : . * . .: : .:. : * .* . . . .. . . :. . . .: *. *****:***********:*******.* ::*:*..:*.:*:*::*** **: : .: : *: *.**: *** *: *. ::**:*:*:* *****.***.*** ***********:**** .* .: * . . . . * * . .: . : .:: :.:*. .. .: .. * ... . : .: **:***:****:. . : : ", "identical_positions": 116, "similar_positions": 149, "identity": "12.2%" }, { "cls_id": "homologset.agr.FB:FBgn0010768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3ATC2-1", "uniprot_id": "A0A8M3ATC2_DANRE", "id": "A0A8M3ATC2-1", "name": "", "aln": "----------------MHFRCFKDTAGVMEDSHFSSSYFWSPV----------------QGQIENAVFLNKVKEQLGHDKSPTYSHGPAHYPPTAVVAVAGGPMEAP--TSRTLKQE----------------------HVQPSHSSHSITVVPVPPSGIMTAAGLVT-----LVSPVSSAQSLIPGHP--SMITVQTD------------------KKNDSLPCSPVIIPLPSKRGRKKKETLPLVG------SPTGTDPLILG---------LSGQHLSTHPYSLSPEEG-HAGKEGSKTYRCRMCGLTFCSKSDMQLHSKSHTEVKAHQCPHCSKSFANTSYLAQHIRIHSGAKPYTCSY--CQKAFRQLSHLQQHTRNHTESKPHKCPHCTKSFANSSYLAQHVRIHTG---VKPYTCNYCEKTFRQLSHLQQHHRIHTGDRP----YKCTHMGCEKSFTQLSNLQSHRRQHNKDKPYKCHHCNRGYVDAAGLDIHLSTHTVKHAKLYSCG----LCHRTYTSETYLMKHMQKHAP-------------DMLPSPPG-SNQHSHSPGRAGGSGS-EGDGQSR---------------IERSDVFVQPIS------VPCVYDMNQYKPVPAADVQYKTVSVSDISPHKDLC-------------ITVEASAIQANHLNS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B5Y0-1", "uniprot_id": "A0A8M2B5Y0_DANRE", "id": "A0A8M2B5Y0-1", "name": "", "aln": "----------------------------MEDSHFNSSYFWSPVPT-------------VQGQIDNAMFLSKMKEQLGPDKAGSFPHSSAAHYPTAVLTVPGSVAMDTGAVGRVPKQESGGGGGGGGGGSAGAQMTGVGAHLHPPHTSQNITVVPVPSTGIMTAAGLVITPQGTLVSPPASSQSFVSGPPTTTMIVSALHPSNTEAVRPPSLYLHSHYKKEDGSIPPAVVMPIPSKRGRKKKSMMPRAGPVSAHALASGSDALILAH------LAAGGQHNTNDPYDLSNDEDEHQGKDGNKSYRCRMCAVTFFSKSDMQIHAKSHTEAKPHKCPHCSKSFANSSYLAQHIRIHSGAKPYTCSY--CQKTFRQLSHLQQHTRNHTEGKPHKCPHCSKSFANSSYLAQHIRIHSG---AKPYTCSYCQKTFRQLSHLQQHNRIHTGDRP----YKCVHPGCEKAFTQLSNLQSHRRQHNKDKPYKCHNCNRGYTDATSLEVHLTTHTVKHAKLYSCG----LCNRSYTSETYLMKHMQKHNP-------------DPLTVAAAVAAQQAQNPGQGSGGGSGRGRGRGRGAAAAAAAAAAAAAQAQNQNNPTPPTSYSVSDGIPCPFDLHQYKTVSAGEIQYKPVTVADLTAHKDLC-------------LTVSTSAIQVEHMNS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDZ3-1", "uniprot_id": "SQZ_DROME", "id": "Q9VDZ3-1", "name": "Zinc finger protein squeeze", "aln": "---------------------------------------MAELPT-------------APNGVPSGDYLHRSIDQLRSLGHLTTAQLVHDYKPFNISEFRQNVAERLDYSLKN----------------------------GLVQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHPPQLKVSYSAPNSPP---------------------------------TPHEQQEQKYDPNRSPPRQQMSSASG---------------------------SGSNGSSP-----EEESRRGDGDQAKPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEKAEKQQHRHTAQVAAHQQHVPASGIGLNLQRQAMNDVNAAYWAKMGADSAAASLAEAIQQQLPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSHSPHEEAAGEDLVLRQSTPQHHLQQQQQQQQQQQAQQQQQAQHQPSPGPGNSAFTPLSATVAPPPHLQQHRGPPGSAAAYLYQQNAAAAAAAFPTQLISLHQIRNYAHQPG---AAGLIAGDHLALGLSAVNAAKEKAQ----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53968-1", "uniprot_id": "CRZ1_YEAST", "id": "P53968-1", "name": "Transcriptional regulator CRZ1", "aln": "MSFSNGNMASYMTSSNGEEQSINNKNDIDDNSAYRRNNFRNSSNSGSHTFQLSDLDLDVDMRMDSANSSEKISKNLSSGIPDSFDSNVNSLLSPSSGSYSADLNYQSLYKPDLPQQQLQ---------QQQLQQQQQQQQQQQQQQQKQTPTLKVEQSDTFQWDDILTPADNQHRPSLTNQFLSPRSNYDGTTRSSGIDSNYSDTESN-----YHTPYLYPQDLVSSPAMSHLTANNDDFDDLLSVASMNSNYLLPVNSHGYKHISNLDELDDLLSLTYSDNNLLSASNNSDFNNSNNGIINTADTQNSTIAINKSKVGTNQKMLLTIPTSSTPSPSTHAAPVTPIISIQEFNEGHFPVKNEDDGTLQLKVRDNESYSATNNNNLLRPDDNDYNNEALSDIDRSFEDIINGRKLKLKKSRRRSSQTSNNSFTSRRSSRSRSISPDEK----AKSISANREKLLEMADLLPSSENDNNRERYDNDSKTSYNTINSSNFNEDNNNNNLLTSKPKIESGIVNIKNELDDTSKDLGILLDIDSLG---------QFEQKVGFKNDDNHENNDNGTFSVKKNDNLEKLDSVTNNRKNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRRCITPLYEEARQEKSGQES", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : .:* : . . : .:. .. : . . . .. .. . . . . :.. . . : . ..* : : : . . : : : . . : * * . : : .. . :. : :* . :.::: :.: *. . .. : ..: : : . : .: . : . : : . . .:: . : : : . : :. . * : : .: .. . . . : . * : . . * : :: ", "identical_positions": 9, "similar_positions": 116, "identity": "1.28%" }, { "cls_id": "homologset.agr.FB:FBgn0010770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YU8-1", "uniprot_id": "SSF1_MOUSE", "id": "Q91YU8-1", "name": "Suppressor of SWI4 1 homolog", "aln": "MGQSGRSRHQKRNRAQAQLRNLESYAAQPHSFVFTRGRAGRNVRQLSLDVRRVMEPLTATRLQVRKKNSLKDCVAVAGPLGVTHFLILTKTDNS--VYLKLMRLPGGPTLTFQISKYTLIRDVVSSLRR-HRMHEQQFNHPPLLVLNSFGPQGM---------HIKLMATMFQNLFPSINVHTVNLNTIKRCLLINYNPDSQELDFRHYSVKVVPVGASRGMKKLLQEK------FPNMSRLQDISELLAT---GVGLSDSEVEPDGEHNTTELPQAVAGRGNMQ--------------------------------------AQQSAVRLTEIGPRMTLQLIKIQEGVGNGNVLFHSFVHKTEEELQAILAAKEEKLRLKAQRQNQQAENLQRKQELREAHKKKSLAGIKRARAR-ADGDSDAEDPGAPPEAVGAGQPEDEEDDAEYFRQAVGEEPDEDLFPTAAKRRRQGGPLG-----KKQRGKEQRPGNKGRGQGGN--WQALKLQGRSQRGKAKPRPRATHQDS---RPASRRRN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ55-1", "uniprot_id": "SSF1_HUMAN", "id": "Q9NQ55-1", "name": "Suppressor of SWI4 1 homolog", "aln": "MGQSGRSRHQKRARAQAQLRNLEAYAANPHSFVFTRGCTGRNIRQLSLDVRRVMEPLTASRLQVRKKNSLKDCVAVAGPLGVTHFLILSKTETN--VYFKLMRLPGGPTLTFQVKKYSLVRDVVSSLRR-HRMHEQQFAHPPLLVLNSFGPHGM---------HVKLMATMFQNLFPSINVHKVNLNTIKRCLLIDYNPDSQELDFRHYSIKVVPVGASRGMKKLLQEK------FPNMSRLQDISELLAT---GAGLSESEAEPDGDHNITELPQAVAGRGNMR--------------------------------------AQQSAVRLTEIGPRMTLQLIKVQEGVGEGKVMFHSFVSKTEEELQAILEAKEKKLRLKAQRQAQQAQNVQRKQEQREAHRKKSLEGMKKARVGGSDEEASGIPSRTASLELGEDDDEQEDDDIEYFCQAVGEAPSEDLFPEAKQKRLAKSPGR-----KRKRWEMDR----GRGRLCD--QKFPKTKDKSQGAQARRGPRGASRDGG--RGRGRGRPGKRVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDE5-1", "uniprot_id": "PPAN_DROME", "id": "Q9VDE5-1", "name": "Protein Peter pan", "aln": "MGGK-KKVHPKTRTAAFKASEPSEIVEAPHSFVIHRGLACPYITDLTLDFRRIMEPFTASNLREKRMNRIKDFVSLSSFFHVSHMGIFNKASTQ--LSFKVVRLPRGPSLTFKVHQFTLARDVISLSKK-QMIDNDHFKHAPLVIMNNFSGDGK---------HLKLMATTFQNMFPSINLATVNIGTIRRCVLFSYNPDTKLVEMRHYSVQVVPVGLKRAVQKIVKGT------VPNLGKCNEVVDFVTK---DGYASESEAE-DDEQSHVVLAQTLKSKGNLE--------------------------------------DKKSSIKLHEIGPRLTMQLIKIEEGLLTGEVLYHDHVVKTEDEKETLRKLVEKKRKQKEQRKKEQAENRARNLKLKKDEK----WAAKRAAEGRTDSDP--------------------EDDAEYYKEEVGEEPDEELFKMEAKSSRKRPSLGGGMKYKNKRAKLDTKDKNDKSERTDKYDRKDKFDRKDKKDKFDPKNRRAKFDPKNKRAKFDHRKSRKSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12153-1", "uniprot_id": "SSF2_YEAST", "id": "Q12153-1", "name": "Ribosome biogenesis protein SSF2", "aln": "---MAKRRQKKRTHAQITPEQERDIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAVKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSDEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRIFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQTSLSQKTPVKMTDNEEREKGIEEEDVEMEEPKPSENSQPTPRKKAIKLTELGPRLTLKLVKIEDGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRRKEQEENIAKKKAVKDAKKQRKLERRKARAEEQGEGQGKD----------GAMSDDGSSSSEDEHYSDVPEDLDSDLFSEVE-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38789-1", "uniprot_id": "SSF1_YEAST", "id": "P38789-1", "name": "Ribosome biogenesis protein SSF1", "aln": "---MAKRRQKKRTHAQLTPEQEQGIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSGEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRVFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTELGPRLTLKLVKIEEGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKKKAVKDAKKQRKLERRKARAAEGGEGQGKD----------DAMSDDESSSSDSEHYGSVPEDLDSDLFSEVE-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * : * . : : :* *.*::*:* ** .*: :: * :** * :.. : *:*: ::.::.. : :*: * * **::**:: .::* **: . :: : :.::.. :.**:::*.*. *::.: ***:**.:* ..:.:*:* .::. : :: :.:*** :.: * .* :::: : . .**: : ::: .:: . *:** * * . :. :.: ::.:::* *:***:*::*:*:::*: *:*:.*..* *:.:* ::: * : * **: :* :* :: :. .: * : : ... . . * * ..:** ", "identical_positions": 78, "similar_positions": 153, "identity": "14.31%" }, { "cls_id": "homologset.agr.FB:FBgn0010772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAF2-1", "uniprot_id": "F1MAF2_RAT", "id": "F1MAF2-1", "name": "", "aln": "---------------------------------------------------------------------------MSSATIVHDPSEAVPLCPALGLYLKPIARVTISVSLPPPPPAPPPSPSSTSPPPRAPSRAVSNWEVMEGLRAMAQGARAPLSSLRLARGGPEVVRFEGEVENRALVRPALAGLDGKTMMLSGLPHGLRVSAAEATP--PPTDD---------------PAHPHDTIHLQGLPCRWFAPRGGSGGDEAGGISSPGGIASAERPSEALLRQAFGAFGEIRHVDIPMLDPYLGEDGS-----HGGGGGGRLRFEAYVQYRERDAYARAMAALRGAKLMFRGTDGKAVACGIKVTSDATQHLSEASIRRRQLERQKLQELEQRREEQKRKEREDEARRRAGQRKQREAEQQQRARRREEKLRRREA-RQRARKRRGRRREEEEEEEEAEPQPVLGREEEEGAEPRRLLLAQRNLQSVRLIAALLARAEAARRRQREQS--------------------------EERRRHAKEAELRRQQEAELRRQREAELRRVE-----------------------EEKRRALGLQRRERELR----------HRLLALLLARGPGLGCLVGGAGTG-SDVLG-AGNSKMAVGSGHGEAGQSQTMTGSEIRGDGREN--MKTGSDVATSGNGHIDRENE-------------------------------KIKTGSGIPATGGGTGDPRGADKQTGSSVQPTGSDAKTGNGARGTGGGPGRDPIAKTWSENMTTGSGSPETGSGVAKMATVSASNETESSS-AKLKAMPSSC-------------------------------SDRERCGLEGRPSWHSRDFGGS-SGQSRSREGSERRRPHEEEDGGGRDRKRGHRHREDRGRSRSRSPRRR----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02040-1", "uniprot_id": "AK17A_HUMAN", "id": "Q02040-1", "name": "A-kinase anchor protein 17A", "aln": "---------------------------------------------------------------------------MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALP---------------QLKQPGKSISNWEVMERLKGMVQ--NHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKIDFPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALK------ESG----------SEKPSEDVLVKVFEKFGEIRNVDIPMLDPYREEMTGRN--FHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ-KQRDRELRRNQKKLEKLQAEEQKQ----LQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQK--------------------------EEK--------LRLQQQEERRRLQEAELRRVE-----------------------EEKERALGLQRKERELR----------ERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAP-------------------------------CKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGR-ATGDGLADRHKRERSRARRASSREDGRPRKERR-------------------------------PHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSR-HRRRSERSRSRSPSRHRSTWNR------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2A3V1-1", "uniprot_id": "AK17B_MOUSE", "id": "A2A3V1-1", "name": "A-kinase anchor protein 17B", "aln": "----------------------------------------------------------------------------MTVTVVYDNSEATELCAAQHLYLKPIAKLMINVLLP---------------ECIEPVRPFSNWEVLDQLKSLICP--DQFTTVRLSKSTKDFIRFEGEAETRSLVQILKAKLHGKIIKLNGLKTDLKVVATDAQGEWEHFPK-EKEASVIEGAEEQDHDKGPDSIYFEGLPCKWFAPKG----------------SSGEKPCEEILRVVFESFGKIKNVDIPMLDPYREVMTGGS--FGGLNFG-LQTFEAFIQYQESTDFIKAMESLRGMKLMLKGDDGKALACNIKVMFDTTKHFSEGAIQRRNQERLKLQELEEERKKEKKREEE------VAERKRKDEVRKAQEKRKKARDRRRAL-KERDRHRQRKEKVKTKPEARQELD------SSGEWEERKYLLARRRVEALRLLRVLLKKIAVWMRKEKNLKPCQTHISLLLNCLGSTQCNPQEVGVMKSEAHHTPGTALKSPEEEELNTRHLLDWEEMPSYQASTLDLSQKAEKRCYQASKSDNKQKQKGKKKTKAQLQKSSHTPGVKQMRHSARKEETGKVLSDGCDYSLVSDQNSLQSTMIADQSLAKEDHASSNESHSSRQAVINRGRKQKIYETDEFIDYLLNYYQTPEYARFCLEASHLTSTCQWQRDVYAKGDGFQIYLRKQGYHSNSLSEEESLQGIEQDEEQDWPQVYIKDPESKSQKTGKINYAKEFTKKLKNHCKDIASETDEHLSPTDGESYPVEKIHSHGVKDSQHIRKSPVSSSLRSVDVGLPLADFLEEISSDSECFSETLSMNQEEEERSMAVYNSSPEKRPLGTDKISTCKQKTKSSQQTLCSEWKHDNEGKYSKHRVRAPGKRSKSELRYSWLEEEGDSIRVDKNISKTRGKLAPKHMLDEGQYHESSSSDELESTTRKKRRLTSGMFDQNVKYRPLHMPSMPPKRARAFYLGYFSRKRQTPWKSEYNQDVRRFKRYENSEDYTLDSDNYYVSHDDNQEHIEYGSYLGDSYSSSLYFKMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LNU6-1", "uniprot_id": "A0ABK0LNU6_RAT", "id": "A0ABK0LNU6-1", "name": "", "aln": "MWFQCEGMNGPWRAVEAWCLVAGLELPQKSSERPLVKPQMQWRRQDIRDFRIVGYPLGTVGGVKWSLSKSRWCEDTMTVTVVYDNSEATELCAAQHLYLKPIAKLMINVLLP---------------ECIEPVRPFSNWEVLDQLKSLICP--DQFTTVRLSKSTKDFIRFEGEAETRSLVQILKAKLHGKIIKLNGLKTDLKVVATDAQGEWEHFPK-EKEASVIEGAEEQDHDKSPDSIYFEGLPCKWFAPKG----------------SSGEKPCEEILRVVFESFGKIKNVDIPMLDPYREVMTGGS--FGGFNFG-LQTFEAFIQYQESTDFIKAMESLRGMKLMLKGDDGKALACNIKVMFDTTKHFSEGAIQRRNQERLKLQELEEERKKEKKREEE------VAERKRKDEVRKAQEKRKKARDRRRAL-KERDRHRQRREKVKAKSEARQEQE------SSGEWEERKYLLARRRVEALRLLRVLLKKIAVWMRKEKNLEPCQTHISLLLNCLGSTQCNPQEVDTMESDAHHTPGTTVKSPEEEESNTQHLLDQKEMPRHQIP----------------KSDGKQKQKVKKRTKTQLQKSSHSPGAKQIRYSARKEETGKGLTDGCDYSLVSDQDSLQSTVTPDQSLEKEDQCSANESHSSRQVVRNRGRKQKIYETDEFIDYLLNYYQTPEYARFCLEASHLPSTCQWQRDVYAKGDGFQIYLRKQRSHSDSLSEVESLQEKELDEEQGWPEMYMKGPESTPQKTGKMNYAKEFTKKLKNHYKDISSESDEHLSLPEGENYPVEKIHSHGVRDSQHTRKSPASSSLRSVDVGLPLADFLEEISSDSECFSETLSMN-EEEERSVAVYNSSPEKRPLGTDRIGRGKQKTRSSQQTLCSEWKYDSEEKYSKHKVRAPGKRSKYELRYSWLEDECDSVRVDKNVSKTRGKVAPKYMCDEGYYHESSSSDEAENTTRKRRRLSSSVFDQNVKYRPLPMPLMPPKRARAFCLGYFSRKRQNPWKSDYNQDVRRFKRYESSEDYMLDPDNYYVSHDDKQEHIEYGRYLGDSYSGSLYFKMC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7KTT0-1", "uniprot_id": "Q7KTT0_DROME", "id": "Q7KTT0-1", "name": "", "aln": "---------------------------------------------------------------------------MTHIQTIENVADCIPFYLPHSLYLKPLAKMQISVSLP----------------TIKSGKSVSNLEIMDKLGAELKP--DKFLLLKVSKSTVNTIRLEAELDERKRLRAAIQRLDGISLRISGFSESFRVRCAESKDDFPTRHDWDSYFRDARNMDEMKAGERPDTIHISHLPMRWFCPRHS-------------EHEENVKPSENIFKRIFEKFGRVRMVDIPICDPYRKSMQADINGMRTFSFEQDVLFEGYVQFEEYSSFVRAMDEFRGNKLVRKFVD-KTQAINICVSFDKQKHLSDSNIQRRERIRKKFIAKAKAEDEER------------EKLKKQQEEELDRERQKQEELKKAEAEKQREREERRKEKHMKKIQERGQVEIS----QKIRIEERKLMIAQRKLESIRTLEKLFERIQLKQRDKNRRVK-------------------------QDDDKDIQRGRLVEKYKAATEKLVCDQRKIVQ---------------------EIKSNTPLLGLLKSKSKKS------AVPVDASSEDEAAASKRHKMGNGVTESAPPGDVNSALNPLNAVAAMAAGAVPGPGGYSAKVASEWMQSLSMFGYGLPGVFTGALYRPPAP-----------------------------FPVSSNYRGFAPRPRGRGRGRGIGIRGSRSGYDTYYNTKHDRYDDENENGYYHRSSRGRNRSRSSSSYSRSRSRSRGRRIVCRSRRSKSRSRSHYRKSSYSSRSRR---------------------------SHSRSSRSRSKTPSQRKNRKLASTRRSRSSSYSRSRSRSHSRRQSSSRRDHRGRHRSSRSNSRSRSHTPKEVILEADKLVASAEKIQRTIDQHTKDRMREEEREIKEKFRHPRTNSHSSNHMDAEPQGEASERRGSISSRSSRRNSLAV-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::. : . *****:::: *.* ** . :..** *::: * . : :::::. : :*:*.* : : :: *.* : :.*: ::* .:: . . *:*::. ** :**. : :*.* :: * **.:: ****: *** . . **.::*:.* : :** :** **: : * *: * .* * * :*:*:. *::*: * *: : ..::: : *::: . : :::: . :: ::* *. : ..: : : . : : .. * *: ::*:*.::::* : *: : :.. :. : : . : . : . : : : : . . . : . :: : . :. . . . . . :.. . : . . . . . .:. . .. . . . . : *: **: ", "identical_positions": 72, "similar_positions": 184, "identity": "6.64%" }, { "cls_id": "homologset.agr.FB:FBgn0010774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A087WNP0-1", "uniprot_id": "A0A087WNP0_MOUSE", "id": "A0A087WNP0-1", "name": "", "aln": "MADKMGLSLEDIIKLNKIQQGCHN--------------------RPDSRVNRGTGPKRYKPGITN------SGRNRLPPYRRPKQLQDKGQHDHFVGSFRAGNHMDTG-GKLLLSNLHFGVSDADIQKLFA-EFGTLRKSAVHYDRSGQSLGTAHVHFERKADALKAMREYNGVPLDGRPMNIQLVTSTIDTRPRPAQSRNRGGMPRNPGSGGYGGGG-TRRETLEDSQGRG-GTSRNSKKKQQQQQQQQQ---------------------------------------------------LSAEELDAQLDTYWEMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2W7J0-1", "uniprot_id": "A0A3B2W7J0_MOUSE", "id": "A0A3B2W7J0-1", "name": "", "aln": "MADKMGLSLEDIIKLNKIQQGRHN--------------------RPDSRVNRGTVPKRYKPAITR------SGRNRLPPYRRPKHLPDKGQHDHFVGSFRAENHMDTG-GKLLLSNLHFGVSDADIQKLFA-EFGTLRKSAVHYDRSGQSLGTAHVHFERKADALKAMREYNGVPLDGHPMNIQLVTSTIDTRPRPAQSRNRGGMPRNPGSGGYGGGG-TRRETLGDSQGRG-GTSSNSKKQQQQQQQQTQ---------------------------------------------------LSAEELDAQLDTYWEMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZY4-1", "uniprot_id": "E9PZY4_MOUSE", "id": "E9PZY4-1", "name": "", "aln": "MADKMDMSLEDIIKLNKMQQGRRD--------------------RPDSRVKRGTGPKRYRPAFTH------GGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTG-GKLFLSNLHFGVSDADIQLLFA-EFGTLKKSAVHYDRCGRSLGTAHVHFERKADALKAMREYNGAPLDGRPMNIHLVTSQIDRQGRPALNSDKGGMTRNPGSGVLSGGG-TKRWTLGGSQGSGRGTSRNSKLQQQQQQQQQQ-------EEQKHQKQQQQKQQQQQQKQGQNHQHQQQQKEQQQQQQQKELQQLSVEELDAQLDYYQDMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K9J7E2-1", "uniprot_id": "K9J7E2_MOUSE", "id": "K9J7E2-1", "name": "", "aln": "MADKMDMSLEDILKLNKMQQGRLD--------------------RPDSRVKRGTGPKRYRPAFTH------DGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTG-GKLFLSNLHFGVSDADIQLLFA-EFGTLKKSAVHYDRCGRSLGTAHVHFERKADALKAMREYNGAPLDGRPMNIHLVTSQIDRQGRPALNSDKGGMTRNPGSGVLSGGG-NKRWTLGGSQGRGRGTSRNSKLQQQQQQQQQQQQQQQQQEEQKHQKQQQQKQQQQQQKQGQNHQHQQQQKE-------KELQQLSVEELDAQLDAYQEMMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RBB1-1", "uniprot_id": "M0RBB1_RAT", "id": "M0RBB1-1", "name": "", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAV--QAAARVNRGGGPMRNRPAIARG-AAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRGGMTRNRGSGSFGGGG-TRRGTRGGSRGRGRGTGRNSKQQ------------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08583-1", "uniprot_id": "THOC4_MOUSE", "id": "O08583-1", "name": "THO complex subunit 4", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAV--QAAARVNRGGGPMRNRPAIARG-AAGGG-RNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRGGMTRNRGSGGFGGGG-TRRGTRGGSRGRGRGTGRNSKQQ------------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86V81-1", "uniprot_id": "THOC4_HUMAN", "id": "Q86V81-1", "name": "THO complex subunit 4", "aln": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGGA--QAAARVNRGGGPIRNRPAIARG-AAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETG-GKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDAQRRPAQSVNRGGMTRNRGAGGFGGGGGTRRGTRGGARGRGRGAGRNSKQQ------------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJW6-1", "uniprot_id": "ALRF2_MOUSE", "id": "Q9JJW6-1", "name": "Aly/REF export factor 2", "aln": "MADKMDMSLDDIIKLNRNQR----------------------------RVNRGGGPRRNRPAIAR------GGRNRPAPYSRPKPLPDKWQHDLFDSGCGGGEGVETG-AKLLVSNLDFGVSDADIQELFA-EFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQYKGVPLDGRPMDIQLVASQIDPQRRPAQSGNRGGMTRSRGSGGFGGRG---------SQGRGRGTGRNSKQQQ-----------------------------------------------------------LSAEELDAQLDAYNARMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V3E7-1", "uniprot_id": "Q9V3E7_DROME", "id": "Q9V3E7-1", "name": "", "aln": "MVDKIEMSLDDIIKSTRSQKKPQAARGGPGGARKTGGQQRFAGGARRGGANAGGSPRKPGSVLKGPRGGVAAGAVQKAKFPR-GDVNSAWKHDMYDGPKRGAVGGGSGPTRLIVGNLDYGVSNTDIKELFN-DFGPIKKAAVHYDRSGRSLGTADVIFERRADALKAIKQYHGVPLDGRPMTIQLAVSDVAVLTRPVAATDVKRRVGGTAPTSFKRGG----GQAGGTARRGFKRPVGGKPAAGGQRRERK-------------------------------------------------APPTAEELDAELDSYINDMKI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12159-1", "uniprot_id": "YRA1_YEAST", "id": "Q12159-1", "name": "RNA annealing protein YRA1", "aln": "MSANLDKSLDEIIGSNKAGSNRAR-----------------------VGGTRGNGPRRVGKQVGS---------QRRSLPNRRGPIRKNTRAPPNAVARVAKLLDTTREVKVNVEGLPRDIKQDAVREFFASQVGGVQRVLLSYNERGQSTGMANITFKNGELARRAVERFNGSPIDGGRSRLRLN-LIVDPNQRPVKSLADR-IKAMPQKGGNAPRPVKRGPNRKAAMAKSQNKPKREKPAK-----------------------------------------------------------KSLEDLDKEMADYFEKK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: **::*: .: . * * : . : . * : . : . : :: : .* .:.: :: :* :.* ::: : *:. *:* * *.: *:. * :*:..::* *:** ::* : **. : . * : *:** :: * ", "identical_positions": 30, "similar_positions": 58, "identity": "9.32%" }, { "cls_id": "homologset.agr.FB:FBgn0010786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19356-1", "uniprot_id": "HEM3_RAT", "id": "P19356-1", "name": "Porphobilinogen deaminase", "aln": "MSGNGGAATTAEENGSMMRVIRVGTRKSQLARIQTDTVVAMLKTLYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNE----VDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDEQL-EFSAIILAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMK------DGQ---LYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGP------------------------------------------------------------------------------------------------EDDPQLVGITARNIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGAQLAAENLGISLASLLLNKGAKNILDVARQLNDVR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22907-1", "uniprot_id": "HEM3_MOUSE", "id": "P22907-1", "name": "Porphobilinogen deaminase", "aln": "MSGNGGAATTAEENGSKMRVIRVGTRKSQLARIQTDTVVAMLKALYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNE----VDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDELQ-EFSAIVLAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVSVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMK------DGQ---LYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGP------------------------------------------------------------------------------------------------EDDPQLVGITARNIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGAQLAAENLGISLASLLLNKGAKNILDVARQLNDVR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08397-1", "uniprot_id": "HEM3_HUMAN", "id": "P08397-1", "name": "Porphobilinogen deaminase", "aln": "MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNE----VDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQ-EFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMK------DGQ---LYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGP------------------------------------------------------------------------------------------------EDDPQLVGITARNIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGPQLAAQNLGISLANLLLSKGAKNILDVARQLNDAH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3W7-1", "uniprot_id": "A0A8M2B3W7_DANRE", "id": "A0A8M2B3W7-1", "name": "Porphobilinogen deaminase", "aln": "-MADGPYKYARDSDGRVSRVIRVGTRKSQLARIQTDSVVEKLKELYPDVLFEIVAMSTTGDKILDTALSKIGEKSLFTKELENALEKNE----VDLVVHSLKDLPTVLPGGFTIGAVLKRENPHDAVVLHPKNKGKRLDSLSNKSVIGTSSLRRAAQLKKRFPHLEFKDIRGNLNTRLKKLDENN-DFSAIILAAAGLKRMGWENRISQILGPEDCMYAVGQGALAVEVRARDLDILEMVSVLNDSDTALSCIAERAFLKHLEGGCSVPVAVHSEVK------NSQ---LYLTGAVYSLDGSDSLKETMQTSFNPDTQAEEQEKV----------------------------------------------------------------------------------------------DEKVQRLGITALKVP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAAQDAAMKLGVDLGNLLLSKGAKEILTVARQLNDAR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0G4-1", "uniprot_id": "Q9W0G4_DROME", "id": "Q9W0G4-1", "name": "hydroxymethylbilane synthase", "aln": "-------------MSAQEKVIRVGSRKSELALIQTKHVIGRLQKLYPKQKFEIHTMSTFGDRVLNVSLPKIGEKSLFTRDLEDALRNGG----VDFVVHSLKDLPTALPTGMAIGAVLEREDARDALVLRENFKGHTIASLPKGSVIGTSSLRRTAQIRRMYPHLTVCDIRGNLNTRLAKLDAADSKFSGIILAQAGLVRMGWMSRISQVLEPTDLLYAVGQGALAVECRANDDQVLAMLQKLMCLNTTCRILAERSFLKTLGGGCSAPVAVWSNLKGEPLNGNSQEVGLSLTGAVWSLDGAIEIRNHLACALNEQKLEGDQRKRGAQEATSQLQEETSSSCDSPPATKRARNGNDSSGSDSNSSSPRQQGSPPVICEDAAACAALSGYTVDQLSDLASHCPVLSNNNAVGPTGVSGGGDADTNNVNTTPRQCPLRLVGGQEVMGQCPVPHNQAMVPAKCPVAHADSGDSFSAKSGSGGESATTAHCPLQMPVGQDFMGECPYVNNDVKVSFAQAGKCPVTGGVAGASASILPTPPSSRASNASSAGDEVDNVATSSKCPFAAMHQGSGLEAPAKDNGNAATAKCPFLQKTVQMFDYADEEQPTPQHSVLIEDVENLFCGLYQHACHSRGIYEKANQLGKTLAEDLIKRGALDVMKVAQAEIHGKVASS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28789-1", "uniprot_id": "HEM3_YEAST", "id": "P28789-1", "name": "Porphobilinogen deaminase", "aln": "-------------MGP--ETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQTRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYN-------EETKKLLLKAIVVDVEGTEAVEDEIEMLIEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKEDSMACGKILAERMIADGAKKILDEIN-LDRIK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:::* ***:** **:. *: :: ** :: ::.* **:: .* .:* *:*:*::**. * :. :*::******:** ** *: :*.: :* :. *.:*: : : *.. . :****:** **::: :*** . .:***::*** *** :. *:** *** *** .*: * : . :*******.:* * * .:: :: : :: ::**:::: * ****.*:.* : : : * *.. * .::*: :.: : :. : * *.. :: ** .:: . : ", "identical_positions": 97, "similar_positions": 111, "identity": "14.5%" }, { "cls_id": "homologset.agr.FB:FBgn0010803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32921-1", "uniprot_id": "SYWC_MOUSE", "id": "P32921-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "MADMPSGESCTSPLELFNSIATQGELVRSLKAGNAPKDEIDSAVKMLLSLKMSYKAAMGEEYKAGCPPGNPTAGRNCDSDATKASEDFVDPWTVR-----TSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFNVPLVIQMSDDEKYLWKD-LTLEQAYSYTVENAKDIIACGFDINKTFIFSDLEYMGQSPGFYRNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDRLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMTPRQLSFHFQCFCFDT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7B0-1", "uniprot_id": "SYWC_RAT", "id": "Q6P7B0-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "MADMPSGESCTSPLELFNSIAAQGELVRSLKAGNAPKDEIESAVKMLLSLKMNYKTAMGEEYKAGCPPGNSTAGSNGDPDATKASEDFVDPWTVR-----TSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFDVPLVIQMSDDEKYLWKD-LTLEQAYSYTVENAKDIIACGFDVNKTFIFSDLEYMGQSPGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDSLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMAPRQLSFHFQCFCFDT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23381-1", "uniprot_id": "SYWC_HUMAN", "id": "P23381-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---MPNSEP-ASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQ-----TSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKD-LTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBS3-1", "uniprot_id": "SYWC_DANRE", "id": "Q6PBS3-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---------MSSPLDLYECVTAQGETVRSIKAKKGSKEEVDAAVQVLLQMKLDYKRVTGQDYKAGCPPQDGVTPQDG--AAPQDGEDQVDPWSVS-----SSSAKGVDYEKLIVRFGSSKVDQELVDRISRLTGKTPHRFLRRGIFFSHRDMHQILDAFEQQKPFYLYTGRGPSSQAIHVGHLIPFIFTKWLQDVFDVPLVIQLTDDEKYLWKD-LTLEECRRFTVENARDIIACGFDVNKTFIFSDLEYMGASPAFYRNVVKVQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFGDRKDVQCLIPCAIDQDPYFRMTRDVAPRIGYLKPALLHSTFFPALQGAQTKMSASDANSTIFLTDTPKQIKNKVNKHAFSGGKDTIEEHRKLGGDPDVDVSFMYLTFFLEDDEQLEKIRQDYSSGAMLTGELKKSLIDTLQPIIAEHQEKRKHVTDDIVQQFMTPRKLHFSC----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KI98-1", "uniprot_id": "Q0KI98_DROME", "id": "Q0KI98-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MADTKETVVEGVEALTLNGK--------PDAEPVETGTDAQAQEGATAPTEDVVDPWNVA-----SSNDAGVDYDKLIKRFGSSKIDEELIARFEKITGKPAHHFIRRGMFFSHRDLHTILTLREQGKPFYLYTGRGPSSGSLHVGHLVPFIMTKWLQETFDVPLVIQLTDDEKTLWKD-LKVEDAIKLGRENAKDIVAIGFDVNKTFIFNNLEFVGKCPAMYQNIIRIQKCVTFNQVKGIFGFGDSDIIGKIGFPAAQAAPAISSTFPFIFGNRK-VHCLIPCAIDQDPYFRMTRDVAPRLGFPKCALIHSTFFPALQGAKTKMSASDQNSAVYLTDTPKQIKNKINKYAFSGGRVSVEEHRKLGGVPEVDVSYQLLKFFLEDDAKLEEVRVAYSKGEMLTGEIKKLAVETLTPIVEQHQAARKLITDEVLDKYFELRPLKFGS----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12109-1", "uniprot_id": "SYWC_YEAST", "id": "Q12109-1", "name": "Tryptophan--tRNA ligase, cytoplasmic", "aln": "---------------------------------MSNDETVEKVTQQVSELK-----------------------------STDVKEQVVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTKPVNEETLKRFKQVTGREPHHFLRKGLFFSERDFTKILDLYEQGKPFFLYTGRGPSSDSMHLGHMIPFVFTKWLQEVFDVPLVIELTDDEKFLFKHKLTINDVKNFARENAKDIIAVGFDPKNTFIFSDLQYMGG--AFYETVVRVSRQITGSTAKAVFGFNDSDCIGKFHFASIQIATAFPSSFPNVLGLPDKTPCLIPCAIDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQKKINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVFLKECYDKYKSGELLSGEMKKLCIETLQEFVKAFQERRAQVDEETLDKFMVPHKLVWGEKERLVAPKPKTKQEKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..: : :. :. *: * ** * . .:**:*** :**:. :::* : *:.: **: .*:*:*:*:***.**: :* *: ***:********* ::*:**::**::*****:.*:*****:::**** *:*. *.::: ***:**:* *** ::****.:*:::* .:*..::::.: :* . .*.:*** *** ***: *.: * *.::..:** :: **************: **** :: . * **:** *******: ******* .:::::***.***:.*:**:*****: : : **::** :***:: *.** :** *:: *..* :*:**:** ::.* :: .* * : :: :.::: : * : ", "identical_positions": 169, "similar_positions": 140, "identity": "34.07%" }, { "cls_id": "homologset.agr.FB:FBgn0010808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7N1-1", "uniprot_id": "MIC25_RAT", "id": "D4A7N1-1", "name": "MICOS complex subunit Mic25", "aln": "MGSSESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQPSAGEQLAPG------------------------------------------------------------------PGPECSVPVPTVPQPTIPVLTVPSP----------------------------------------------------------------------------------------------------------------SVCGPAEGTYKAPQGDFKVSRAENSDGQQSSAVKEDLKKFQQEQLAVQDELVKVARKEKEATEKHLKASLPKKKA--THEQQQ--SDRLT----RELKNREAELSRRDTFYKEQQERIQEKNAELYKLSSQQFHEAASKAESTIK---PRRVEPVCSGLQAQILRCYRDHLHEVLLCSDLAKAYQHCVSTARKG----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VN4-1", "uniprot_id": "MIC25_MOUSE", "id": "Q91VN4-1", "name": "MICOS complex subunit Mic25", "aln": "MGSAESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQPSAGEQLVPG------------------------------------------------------------------FGPSSSAPVPTVPLPAISVPTVPAPTT------------------------------------------------------------------------------------------------------PVPTAPSSSVRGLPGGTCKGPLTDVKVPSAESGGGLQSSAVKEDLKKFQQEQLAVQDEMVRVAKKEKEAAEKHLKASLPKKKASLTHEQQQ--SARLA----RELEDREAELSRRDTFYKEQQGRIQEKNAELYKLSSQQFHEAASKAESTIK---PRRVEPVCSGLQAQILRCYRDHLHEVLLCSDLVKAYQHCVSTARKG----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRQ6-1", "uniprot_id": "MIC25_HUMAN", "id": "Q9BRQ6-1", "name": "MICOS complex subunit MIC25", "aln": "MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKE---------------------------------------------------------------------------------PSSPPPAPTS-----------------------------------------------------------------------------------------------------------------------------STFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQK--SVRLA----RELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIK---PRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63ZW2-1", "uniprot_id": "MC25A_DANRE", "id": "Q63ZW2-1", "name": "MICOS complex subunit mic25a", "aln": "MGSGEST-TRRVSFGLDEDDRVRILRGVKLSEDVLQRMRNT-------------------------------------------------------------------------------NADPRPPANNK--------------------------------------------------------------------------------------------------------------------------------ENQGHQTRTPSTSDAQAPKTQAKTTFPDSKEELKKRYEQQQAIIQEELARIARKEREAARQDISRAVQRERAQTRQESER--AKQLG----KQLDKKEAELKALEAFYQEQITQLEKKNEERFRMSAEQFHAAATRSEANIK---ARNVEPVCLNLQAQILNCYRENREQTLQCSDLAKEYMQCINAAKKNLLVNHG----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BFY9-1", "uniprot_id": "A0A8M2BFY9_DANRE", "id": "A0A8M2BFY9-1", "name": "", "aln": "MGAADSR-SRSVSFGLDEKENVTVLHGVKLSGEVLQRMRES-------------------------------------------------------------------------------GPASSKPASNK--------------------------------------------------------------------------------------------------------------------------------AES-----------AKAETEASRASAAETQEELKRRFEREQVLVQEELSRISQRERESAADEQNTAVLREKTQRQLNNTHNLPDELSFR-ARQLKKKENELKHLEQFYKEQLQLMEKKNSEYYQQNLHMYEKEADKAEATVR---PRPMSPVCSELQSQVLSCYRLNKHQSLLCSQIAREYMNCINSSKKNLLVNHG----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AD55-1", "uniprot_id": "A0A8I6AD55_RAT", "id": "A0A8I6AD55-1", "name": "", "aln": "MGGTAST--RRVTFEADENENITVVKGIRLSENVIDRMKESS--PSGSKSQR-------------------------------------------------------------------YSSVYGASVS---------------------------------------------------------------------------------------------------------------------------DE-ELKRRVAEEL-------------------------ALEQAKMESENQRRLKHARDLEREKAVANEQLTRAILQERISSEENRTKVKHLDIEDK-ARQLEEKDRMIRKQDAFYKEQLSRLEERSSEFYKVTTEEYQKAAEEVESKFR---RYEYHPVCADLQTKILQCYRQNTQQTLSCSALANQYMHCVNHAKQ-NMLEKGG---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRB9-1", "uniprot_id": "MIC19_MOUSE", "id": "Q9CRB9-1", "name": "MICOS complex subunit Mic19", "aln": "MGGTAST--RRVTFEADENENITVVKGIRLSENVIDRMKESS--PSGSKSQR-------------------------------------------------------------------YSSVYGASVS---------------------------------------------------------------------------------------------------------------------------DE-DLKRRVAEEL-------------------------ALEQAKKESEHQRRLKQARDLERERAAANEQLTRAVLRERISSEEERMKAKHL------ARQLEEKDRVMRKQDAFYKEQLARLEERSSEFYKVTTEEYQKAAEEVEAKFK---RYEYHPVCADLQTKILQCYRQNTQQTLSCSALASQYMHCVNHAKQ-SMLEKGG---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX63-1", "uniprot_id": "MIC19_HUMAN", "id": "Q9NX63-1", "name": "MICOS complex subunit MIC19", "aln": "MGGTTST--RRVTFEADENENITVVKGIRLSENVIDRMKESS--PSGSKSQR-------------------------------------------------------------------YSGAYGASVS---------------------------------------------------------------------------------------------------------------------------DE-ELKRRVAEEL-------------------------ALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHL------ARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFK---RYESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHAKQ-SMLEKGG---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J6A6-1", "uniprot_id": "A0AC58J6A6_DANRE", "id": "A0AC58J6A6-1", "name": "", "aln": "MGANNST--RRVSFESDENDNITIVKGIRLSEKVIDRMREPSGPPSPRVPSRPPPASPPVVDPLPALVPISPPPPDPVTLHPPPSLPERVKLPEQVTTPAPPPPPPP------LESVGVLSTPAGESIAPPAAASELLTASPPVDIIASPPSSTLTPSPPIADSVTAPPAFE-----------LFTPAAPLESIPTCPITKPASDLPVELTAPSPPPEPPSSAQTALQPPLTVDQPVVSPTA----PPPPTVDESELRRKITEELRKGLEEDRRKTQEELNQWLEKEKSQAHAKAQAEAQAQVKDEVSRILALEKSGAEETIQKAILRERVSAEDERLQAQIYVSKRANARQLEERDKELRKQDAFYREQVAKLKERSSQFYKVTNENYHKAADEVNAKFK---RYEISPVCTDLQGQILKCYRENAGKTLLCSNIASQYLQCVNHAKQ-EKLRTGG---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IUJ2-1", "uniprot_id": "A0AC58IUJ2_DANRE", "id": "A0AC58IUJ2-1", "name": "", "aln": "MGGNSSS--RHVSLDDEEG--VTFVKGIRLSERVIDRMKESPHVQTSTKTSTQSENTKRSVPDERQVPIMPHPPSYASALVSSEPPASSVPVIEETSTPASPVGHTTGDAHVVLPAEPINIPSTSDSITPPQLPSAPVEPFTPVLTTTTDPESNTTRPITDSLASSVEPVVVQNEGLVAESTTLWSSDLPVENSHFPASIPDSSSSTVVLLDETSSNAMDVSGESPVSCLMPVEEPVVPSISGQVFPSQAHVDEEKLRKEIREDLLKQMSEEMKTAELNIRQQLDKEKAKALSQAQATARRQIEEEVKKLLEEEKTSQQQTLADAIRREQLSVQDERLITQFIFIFSQKAQKLEEKEKDLKNQDDLFRQQIAKMEEKMSKFTKVTSENYKKGLEDAQNRFR---RYRIKPVCSDLQSQILKCYAENKGQTMCCSNIASLYIQCVDRARQDEKLSTGG---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA18-1", "uniprot_id": "Q9VA18_DROME", "id": "Q9VA18-1", "name": "", "aln": "MGARQSQSREPRTVSMENPTPAGVID---ISDDVVKRLKAG-------------------------------------------------------------------------------ISQQAR--------------------------------------------------------------------------------------------------------------------------------------------------------------------EHAAAAEESKPVPKPTTKAAAKPAASSPAASPAPKVSSYPAAVPIYVQGGGHTISAADVQRQMN---QELIKNDELWKERMAKLEENLKKTNTILEKEYANAVENVHKRFVSTASSHKVPPCQDLKSQLLACYRAHPGETLKCIEEVAQFRQCIDLHRVQKLDAEPESSKVTSKATVPAKAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. * . :. :: .: :* *:.*:: . . : :::. : : ::::: ::.. : . : . . * * *: ::* ** . : : * . : .*:. : ", "identical_positions": 14, "similar_positions": 48, "identity": "2.97%" }, { "cls_id": "homologset.agr.FB:FBgn0010825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62901-1", "uniprot_id": "RERE_RAT", "id": "Q62901-1", "name": "Arginine-glutamic acid dipeptide repeats protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLEGGAKNYAESDHSEDEDNDN------------GATTEESARKSRKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPAPALCDPPAC---SLPVASQPPQHLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVI--------------------KNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKL---------------------------------------PDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSE-FLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKH--SMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTEDTDRATSKKTKTQEISRPNSPS--------------EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ-TQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSP-------ATSQPPNQTQSTVAPAAHTLIQQTPTLHPPR--------LPSPHPPLQPMTAPPSQN-SAQPHPQPSLHGQGPPGP--HSLQTGP----LLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHP-HSTIQLPASQSALQPQ---QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------------PALKPLSSLSTHHPPSAHPP------------PLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGG--------LHQVPSQSPFPQHPFVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGNVPGA--------------PSCPLPAVQIKEEALDEAEEPE-------SPPPPPRSPSPEPTVVDTPSHAS----------------------------QSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE-----REREKEKEKEREREREREREAERAAQKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG-PDTPALRTLSEYARPHVMSPTN---RNHPFYMPLNPTDP-LLAYHMPGLYNVDPTIRERELRE------------REIREREIRERELR-ERMKPGFEVKPPELDPLHPATNP-MEHFARHSALTIPP-AAGPHPFASFHPGLNPLERERLALAG-PQLRPEMSYPDRLAAERIHAER-------------------------MASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG--------------SAGPVHPLVDPLTAGPHLARFPYPPGTLPNP------------LLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQ-WLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TZ9-1", "uniprot_id": "RERE_MOUSE", "id": "Q80TZ9-1", "name": "Arginine-glutamic acid dipeptide repeats protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLEGGAKNYAESDHSEDEDNDNN-----------SATTEESNKKSRKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHSSQACCRSPAPAFCDPPAC---SLPVAPQPPQHLSEAGRGPGGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVI--------------------KNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKL---------------------------------------PDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPSKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSE-FLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKH--SMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPS--------------EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ-AQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSP-------ATSQPPNQTQSTVAPAAHTHIQQAPTLHPPR--------LPSPHPPLQPMTAPPSQS-SAQPHPQPSLHSQGPPGP--HSLQTGP----LLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHP-HSTIQLPASQSALQPQ---QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPP------------PALKPLSSLSTHHPPSAHPP------------PLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTG---------LHQVPSQSPFPQHPFVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGSVPGA--------------PSCPLPAVQIKEEALDEAEEPE-------SPPPPPRSPSPEPTVVDTPSHAS----------------------------QSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE-----REREKEKEKEREREREREREAERAA-KASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG-PDTPALRTLSEYARPHVMSPTN---RNHPFYMPLNPTDP-LLAYHMPGLYNVDPTIRERELRE------------REIREREIRERELR-ERMKPGFEVKPPELDPLHPATNP-MEHFARHSALTIPP-AAGPHPFASFHPGLNPLERERLALAG-PQLRPEMSYPDRLAAERIHAER-------------------------MASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG--------------SAGPVHPLVDPLTAGPHLARFPYPPGTLPNP------------LLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQ-WLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2R6-1", "uniprot_id": "RERE_HUMAN", "id": "Q9P2R6-1", "name": "Arginine-glutamic acid dipeptide repeats protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTADKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDNDNN-----------SATAEESTKKNKKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPTPALCDPPAC---SLPVASQPPQHLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVI--------------------KNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKL---------------------------------------PDLQPFPSPDGDTVTQHEELVWMPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESGYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSE-FLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKH--SMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPS--------------EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ-AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP-------TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP-SAPSHAQPPLHGQGPPGP--HSLQAGP----LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP-HTSLQLPASQSALQSQ---QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------------PALKPLSSLSTHHPPSAHPP------------PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG---------LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG--------------SSCPLPTVQIKEEALDDAEEPE-------SPPPPPRSPSPEPTVVDTPSHAS----------------------------QSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE-----REREKEKEKEREREREREREAERAA-KASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG-PDTPALRTLSEYARPHVMSPTN---RNHPFYMPLNPTDP-LLAYHMPGLYNVDPTIRERELRE------------REIREREIRERELR-ERMKPGFEVKPPELDPLHPAANP-MEHFARHSALTIPP-TAGPHPFASFHPGLNPLERERLALAG-PQLRPEMSYPDRLAAERIHAER-------------------------MASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG--------------SAGPVHPLVDPLTAGPHLARFPYPPGTLPNP------------LLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQ-WLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B939-1", "uniprot_id": "A0A8M2B939_DANRE", "id": "A0A8M2B939-1", "name": "Arginine-glutamic acid dipeptide repeats protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTADKEKDKERERDRDRDRDRE--KRDKTRESESSRPRRSCTLEGGAKNYAESEHSEDDDNETPG----------AATAEEATKKSKKKLPKKKSRYERTENGEITSFITEDDIVYRPGDCVYIESRRPNTPYFICSIQDFKLS---------------------------------------------KRDHLLMNVKWYYRQSEVPDSVYQHLVQDRNNENDSGRELVITDPVV--------------------KSRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARIDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKL---------------------------------------PELQPFPSPGGQTVTENEELVWMPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCLAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWSEDEVKRFIKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASCRAHRRHRRQPVFRRIKTRTASTPVNTPSRPPSSE-FLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKH--SMRTRRNRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRTSPSAASTSSTDSKTDSMKKPSKKTKEEAPSPMKSAKRQREKGASDTEESERASAKKSKTQEISVPNSPSE----------CEGEGEGESSDGRSVNDEGSSDPKDIDQDNRSSSPSIPSPRDNESDSDSSAQQQILQGQHPPVIQCQTGTLPPAPPPAAAASTTPTSG-APSLSSQPSPSIP-------PTSMPPQQ----IPPAGPLSLIQS---GVQR--------LPSPHSPLQGMPQPPPPSQTCPQALQPPLHGPMPPMG--HPLQAGPS-HMPHPHALPTQPFPMAQSQVPPSPLSGQAQAASLSQQQRPHTPPSQSQSSSQSGSQPPREQPLPPAPLPMPHIKPPPTTPIPQMPNAQSHKHPSHPPFP---QMPSNLPPP------------PALKPLSSLSNHHPPSAHPP------------PLQLMSQSQQLQPPPVQPPVLTQSQTLPATGSQAPPPAPPLPSSSSASHSAPSQPPFPPHSFMPGSSPVLSPSTVPTSVSSSMTTLQQPPPSISMPLPASVSAPCP--------------GPSTVPPVQIKEEPLDETEEPE-------SPPPPQRSPSPPPTIVNTPSHAS----------------------------QSARFYKHLDRGYNTCARTDFYFTPLASSKLAKKREEALEKAKREAEQKAREE-----KEKEREREKEREREREREKEAERAA-KASSSSHESRMGEPPMAGSAHMRTSFDPPPTTIATVPPYIG-PDTPALRTLSEYARPHVMSPTN---RNHPFFVSLNPTDP-LLAYHLPGLYNADPSMRERELRE------------REIREREIRERELRMERMKPGFEVKPPELDSLHPSANP-MEHFARHGPIGLPP-MAGPHPFASFHPGLNPLERERLALAG-PQLRPEMTYPERLA-ERLHVER-------------------------LAN---DPMARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGGGE------CLVCPPGSGAHPLVDPLAGGPHLARFPYPPGAIPNP------------LLGQPPHEHEMLRHPVFGTPYPRDLPAGLPPPMSAAHQLQAMHAQSAELQRLAMEQQ-WLHGHHHMHGGPLPGQEDYYSRLKKESDKQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54258-1", "uniprot_id": "ATN1_RAT", "id": "P54258-1", "name": "Atrophin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTRQNKDSMSMRS--------------GRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKS---------------RQTAKKARVEETSTPKANKQGRSEEISESESEETSAPKK-TKTE-ELPRPQSP------------------------------------------------------------------------SDLDS-------LDGRSINDDGS----SDPRD--------------------IDQD-------------------NRSTSPSIYSPGSVENDSD-----------------SSSGLSQGPARPYHP---------------------------------------PPLFPPSPPPPDSIPRQPESGFEP----------------------------------HPSVPPTGYHAPMEPPTS---------RLFQGPPPGAPPP------------------------HPQLYPGSAGGGVLSGPPMGPKGGAAASS-------------------VGPPSGGKQHPPPTT-PIPISSSGASGAPPAKPPNTPVGAGN---------------------------------------LPSAPPPATFPHVTP-----------------NLPPPPALRPLNNASASPPGMGAQPIPGHLPSPHAMGQGMSGLPPGPEKGPTLAPSPHPLPPASSSAPGPPMRYPYSSCSSSSVAASSSSSAA---TSQYPASQT------------------LPSYPHSFPPPTSMSVS--NQPPKYTQPSLPS--------------QAVWSQGPPPPPPPYGRLLPNNNTHPGPFPP-TGGQSTAHPPAPAHHHH-------QQQQQPQPQPQP-----QQHHHGN-----------------SGPPPPGAYPHPLESS--NSHHAHPYNMSPSLGSL--RPYPPGP------AHLPPSHGQVSYSQAGPNGPPVSSSSNSSGS--------SSQAAYSCS---HPSSSQGPQGASYPFPPVPPITTS-------------------------SATLSTV------------IATVASSPAGYKTASPPGPP------------QYSKRAPS-PGSYKTATPPGYKPGS--PPSFRTGTPPG-----------YRGTSPPAGPGTFKPGSP------TVGPGPLPPAGPSSLSSLPPPPAAPTTG---------------------PPLTATQIKQEPAEEYETPE-------SPVPPARSPSPPPKVVDVPSHAS----------------------------QSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE-----KEREREREREKEREREKERELERSVKLAQEGRAP---VECPSLGPVPHRPPFEPG-SAVATVPPYLG-PDTPALRTLSEYARPHVMSPGN---RNHPFYVPLGAVDPGLLGYNVPALYSSDPAARER--------------------EREARERDLR-DRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFP-FHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAER-------------------------VAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAA---------------SASVHPLIDPLASGSHLTRIPYPAGTLPNP------------LLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35126-1", "uniprot_id": "ATN1_MOUSE", "id": "O35126-1", "name": "Atrophin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTRQNKDSMSMRS--------------GRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKS---------------RQTAKKARIEEPSAPKASKQGRSEEISESESEETSAPKK-TKTEQELPRPQSP------------------------------------------------------------------------SDLDS-------LDGRSINDDGS----SDPRD--------------------IDQD-------------------NRSTSPSIYSPGSVENDSD-----------------SSSGLSQGPARPYHP---------------------------------------PPLFPPSPPPPDSTPRQPESGFEP----------------------------------HPSVPPTGYHAPMEPPTS---------RLFQGPPPGAPPT------------------------HPQLYPGNASGGVLSGPPMGPKGGAAASS-------------------VGAPSGGKQHPPPTT-PIPISSSGASGAPPAKPPSAPVGGGS---------------------------------------LPSAPPPASFPHVTP-----------------NLPPPPALRPLNNASASPPGMGAQPIPGHLPSPHAMGQGMSGLPPGPEKGPTLAPSPHPLPPASSSAPGPPMRYPYSSSSSSAAASSSSSSSS---ASQYPASQA------------------LPSYPHSFPPPTSMSVS--NQPPKYTQPSLPS--------------QAVWSQGPPPPPP-YGRLLANNNTHPGPFPP-TGGQSTAHPAAPTHHHH-------QQQPQ------------QQHHHGN-----------------SGPPPPGAYPHPLESS--NSHHAHPYNMSPSLGSL--RPYPPGP------AHLPPPHGQVSYNQAGPNGPPVSSS-NSSGS--------SSQASYSCS---HPSSSQGPQGASYPFPPVPPVTTS-------------------------SATLSTV------------IATVASSPAGYKTASPPGPP------------QYSKRAPS-PGSYKTATPPGYKPGS--PPSFRTGTPPG-----------YRGTSPPAGPGTFKPGSP------TVGPGPLPPAGPSSLSSLPPPPAAPTTG---------------------PPLTATQIKQEPAEEYEPPE-------SPVPPARSPSPPPKVVDVPSHAS----------------------------QSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE-----KEREREREREKEREREKERELERSVKLAQEGRAP---VECPSLGPVPHRPPFEPG-SAVATVPPYLG-PDTPALRTLSEYARPHVMSPGN---RNHPFYVPLGAVDPGLLGYNVPALYSSDPAARER--------------------EREARERDLR-DRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFP-FHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAER-------------------------VAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAA---------------SASVHPLIDPLASGSHLTRIPYPAGTLPNP------------LLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54259-1", "uniprot_id": "ATN1_HUMAN", "id": "P54259-1", "name": "Atrophin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTRQNKDSMSMRS--------------GRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKS---------------RQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKK-TKTEQELPRPQSP------------------------------------------------------------------------SDLDS-------LDGRSLNDDGS----SDPRD--------------------IDQD-------------------NRSTSPSIYSPGSVENDSD-----------------SSSGLSQGPARPYHP---------------------------------------PPLFPPSPQPPDSTPRQPEASFEP----------------------------------HPSVTPTGYHAPMEPPTS---------RMFQAPP-GAPPP------------------------HPQLYPG-GTGGVLSGPPMGPKGGGAASS-------------------VGGPNGGKQHPPPTT-PISVSSSGASGAPPTKPPTTPVGGGN---------------------------------------LPSAPPPANFPHVTP-----------------NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA------------------LPSYPHSFPPPTSLSVS--NQPPKYTQPSLPS--------------QAVWSQGPPPPPP-YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHH-------HQQQQQQQQQQQQQQQQQQQHHGN-----------------SGPPPPGAFPHPLEGG--SSHHAHPYAMSPSLGSL--RPYPPGP------AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS--------TSQGSYPCS---HPSPSQGPQGAPYPFPPVPTVTTS-------------------------SATLSTV------------IATVASSPAGYKTASPPGPP------------PYGKRAPS-PGAYKTATPPGYKPGS--PPSFRTGTPPG-----------YRGTSPPAGPGTFKPGSP------TVGPGPLPPAGPSGLPSLPPPPAAPASG---------------------PPLSATQIKQEPAEEYETPE-------SPVPPARSPSPPPKVVDVPSHAS----------------------------QSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE-----KEREREREREKEREREKERELERSVKLAQEGRAP---VECPSLGPVPHRPPFEPG-SAVATVPPYLG-PDTPALRTLSEYARPHVMSPGN---RNHPFYVPLGAVDPGLLGYNVPALYSSDPAARER--------------------EREARERDLR-DRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFP-FHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAER-------------------------VAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAA---------------SASVHPLIDPLASGSHLTRIPYPAGTLPNP------------LLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PHT1-1", "uniprot_id": "M9PHT1_DROME", "id": "M9PHT1-1", "name": "", "aln": "MAASTQGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERELEESRWSPGVVADGDLLMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVKCPVSKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPKRGSETPDVSGGASVDSPKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNSDSRPDSVLDDGESNTTDTTTAEQQSTKDSKETVSCKEEREMVTNDLEAKAEEKAIKAEALAEDSKDSAIKNMDEETNIQAPSSADTSLVDGPNPNALPSPVAAPITMKVPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQHMQQQSQQQMQQQLAPVGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKVKIEIKNEDALKHSAGGLPPSGPCAPPSALHPLSGAPVESGQEPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKYPPEMEMKFAPQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQPPSKPGYQDSLKIPDIKPGFGHLPHNVGSPLDAAHKYGPPPTSQESQQQQPQPPAHQVPPGATPPPGIAMPKPHYQHDVQTPPLGRPFEPTGLMLKYGDPLAAKYGPPQDLKYPMPPVSQAGPADVKPYGGENLIKSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQQFQSPHPSPHMPSPAG--GGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSAGPPSLQHGLHPGHQHSQLSVASSIPPSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPPSMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRTPSPAQQPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPMAIHPHLAHLPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTPPSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSVGPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERDRHALMRQQSPHMTPPPVSNASLMASPLSKMYAPQPGQRGLGTSPPPHLRPGASPPVIRHPQMPLPLPLIAPGGGIPQIGVHPGQSPYPHPLLHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQDEQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPGTPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHPTEPLPIDIEPDPEPEIPSPTHN-IPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRTDLIFKPVADSKLARKREERDRKLAEKERERRQQQQQQQQQQQQQQAAAAQQAAQQAKMKAELKPPYADTPALRQLSEYARPHVAFSPVEQMVPYHHPMGPMYRERELEEIKNAQAAAASQSRLDPHWMEYYRRGIHPSQFPLYANPAISQMERERLGIPPPHHVGLDPGEHMIRLTREYHAHSHTHLHLPLHPQPQPPEAGFQLPPNVGQYPRPNMLIPREPHSDVLLRMSYADQLQYLQAAEFQRQSLHDQYFRNQLR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : ::.: . *: . *. . : .. .. .: : : : .. :: . : : :: . . . *: . : .. *. :*. :: : * : : * :. : ** * : . : . : : * * : .: . : : * . ... . * . * : :. : . . . . * . : :. . . .: : .: .. .* . * . .. . . . . . : . * .. .* * . : ..* :** * : ** * . . : . .. . . * . . * . : ** . . : ..*. * .. : . . : * . . . *. . : ... * . * .. .. . .. .. . .. .. .... . . . . . .: .:. ..: .. .. *: :. ** *.. * :: *. . :.: * . .: :*: * : . . : :: . * ::* : : :: *:: : .: .::. * : . .. .. . . :** :* *.**: . . *. .*: . : :. ** . . :: .* : .. * * . . *. *.** : : : . : : * . :*.. : . **:* * : :: :: . :: :* : ::.*:** . :: . .*.: . : . ** ** ... :::: :* * * : * :. : : * : ..: * ...: :. . * : .: : : . ::. : *. : . :::: ", "identical_positions": 91, "similar_positions": 331, "identity": "4.52%" }, { "cls_id": "homologset.agr.FB:FBgn0010894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NY35-1", "uniprot_id": "CLDN1_HUMAN", "id": "Q9NY35-1", "name": "Claudin domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------MDNRFATAFVIACVLSLISTIYMAASIGTDFWYEYRSPVQENSSDLNKSIWDEFISDEADEKTYNDALFRYNGT----VGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNSGIDLLRTYLWRCQFLLPFVSLGLMCFGA---LIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYRVA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V674-1", "uniprot_id": "G3V674_RAT", "id": "G3V674-1", "name": "Claudin domain-containing protein 1", "aln": "MLSSGSSSFFTGVPTSPTRPLGSGPLWPGLGWRRRRRRGSYGGGGLCREVRQRRRGESRLLWSELEGEAGGVRGWAYAGDRLENKTSVSVASWSSLNARMDNRFATAFVIACVLSLISTIYMAASIGTDFWYEYQSPAQENSSDANRIAWEDFMGDEADEKTYNDALFRYNGN----LGLWRRCITIPKNTHWYAPPERTESFEVVTKCMSFTLNEQFMEKYVDPGNHNSGIDLLRTYLWRCQFLLPFVSLGLMCFGA---LIGLCACVCRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLGLPKNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYRVA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VRM3-1", "uniprot_id": "Q9VRM3_DROME", "id": "Q9VRM3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MQK--PSHFAREDSQEHLPTSHTQNSHTVNMK---RRTLSGSCGVGVFVFAFAFIVIAFATPSWLVSDYRITGAKLDRLGLWVHCFRSLPDVNDDSQRR-------------FFVGCRWVYDPFTTGYDEIRGFLLPAFMIATQFFYTLAFIGMLVSAIGVLVFILCAGPDQKHFITLIKSLGYVLLGAGVSAAIAVIVF-AGFGNRNGWMPEHANNWFGWSFILACVGTVLTLVASTLFLSEAHVQHKKRIQFKESQTRFELVRG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: .: *. . :.* : * .:: : . . ... *: :: : :* .* :*** :*: : : : . * : ::: . . .* .: ** ::: **: .:. :*:: . :: *** :. : *: ..: ::* * . .::: * : ::: :*.:... ***** ****.: * ::**:**: **.::*: :* :. ", "identical_positions": 44, "similar_positions": 90, "identity": "12.05%" }, { "cls_id": "homologset.agr.FB:FBgn0010905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35274-1", "uniprot_id": "NEB2_RAT", "id": "O35274-1", "name": "Neurabin-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKTEPRGPGG-------PLRSASPHRSAYEAGIQALK-PPDAPGPDEAPKAAHH--------KKYGSNVHRIKSMFLQMGTTTGPPGEAGGASGMAEAPRASDRGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSV-----------------PAASGGDKEAVARRLLRQERAS-LQDRKLDVVVRFN-GSTEA-------------------LDKLDA-----DAVSPTVSQLSAVFEKADSRTG------LHR--APGPPRAAGAPQVNSKLVTKRSRVFQPPPPPP-APSGDAATEKDRGPGGQQPPQHRVAPARPPPKPREVRKIKPVEVE-------------------------------------------ESGESEAESAP---------------------GEVIQAEVTVHAALENGSTTATTAS--PAPEEP------------------------------------------------------------------------------------------KAEAVPEEEASSSVATLERGVDNGRAPDMAPEEVD-ESKKEDFSEADLVDVSAYS-----GLGEDSGGSALEEDDEEDEEDGEPPYEPESG---------------------------------------------------------------------------------------------------------------------------------------------------CVEIPGLSEEE---------DPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQER---------------WQREMMEQRYAQYGEDDEE----------TGEYATDEDE-ELSPTFPGGEMAIEVFELAENEDALSPVEMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6R891-1", "uniprot_id": "NEB2_MOUSE", "id": "Q6R891-1", "name": "Neurabin-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKTEPRGPGG-------PLRSASPHRSAYEAGIQALK-PPDAPGPDEAPKAAHH--------KKYGSNVHRIKSMFLQMGTTAGPPGEAGGGAGMAEAPRASDRGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSV-----------------PAASGGDKEAVARRLLRQERAG-LQDRKLDVVVRFN-GSTEA-------------------LDKLDA-----DAVSPTVSQLSAVFEKADSRTG------LHR--APGPPRAAGAPQVNSKLVTKRSRVFQPPPPPP-APSGDGATEKERGPGGQQPPQHRVAPARPPPKPREVRKIKPVEVE-------------------------------------------ESGESEAESAP---------------------GEVIQAEVTVHAALENGSTPATTAS--PAPEEP------------------------------------------------------------------------------------------KAEAVPEEEAAASVATLERGVDNGRAPDMAPEEVD-ESKKEDFSEADLVDVSAYS-----GLGEDSGGSALEEDDEEDEEDGEPPYEPESG---------------------------------------------------------------------------------------------------------------------------------------------------CVEIPGLSEEE---------DPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQER---------------WQREMMEQRYAQYGEDDEE----------TGEYATDEDE-ELSPTFPGGEMAIEVFELAENEDALSPVEMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SB3-1", "uniprot_id": "NEB2_HUMAN", "id": "Q96SB3-1", "name": "Neurabin-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKTEPRGPGG-------PLRSASPHRSAYEAGIQALK-PPDAPGPDEAPKGAHH--------KKYGSNVHRIKSMFLQMGTTAGPSGEAGGGAGLAEAPRASERGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSA-----------------PAAAGGDKEAAARRLLRQERAG-LQDRKLDVVVRFN-GSTEA-------------------LDKLDA-----DAVSPTVSQLSAVFEKADSRTG------LHR--GPGLPRAAGVPQVNSKLVSKRSRVFQPPPPPPPAPSGDAPAEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVE-------------------------------------------ESGESEAESAP---------------------GEVIQAEVTVHAALENGSTVATAAS--PAPEEP------------------------------------------------------------------------------------------KAQAAPEKEAAA-VAPPERGVGNGRAPDVAPEEVD-ESKKEDFSEADLVDVSAYS-----GLGEDSAGSALEEDDEDDEEDGEPPYEPESG---------------------------------------------------------------------------------------------------------------------------------------------------CVEIPGLSEEE---------DPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQER---------------WQREMMEQRYAQYGEDDEE----------TGEYATDEDE-ELSPTFPGGEMAIEVFELAENEDALSPVDMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3J0-1", "uniprot_id": "E7F3J0_DANRE", "id": "E7F3J0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKTEPPSAASGSTNTTLVARSASPHRNAYEAGIQSLK-PVTANGEDGKPRILDRG-------RRYGSNVHRIKNMFMQMGS----PGDEDDPS----KPKDLDQGVRLSLPRASSLNENVDHSALLKLGGTVSERVSRFDGKTEGSSSRGSTAG-YSKLQETRKIFEQRH-----------------LQE---KQAATNRILLKKERASGFQDSRLDVVVRFN-GSTES-------------------LDRLDAGDCPADAVSPTVSQLSAVFERADQRNS------LPRPSSTSPLPSHGAASTSTKVEGISSKTATKKARSIPPTENNEAKDQAGAPGSPK--------SRTSSQP-DASNSKPSEDT-------------------------------------------ASGNTDNISRS---------------------EEILNSSGCDSKQGEN----SEPGS--PDPGSR------------------------------------------------------------------------------------------LVQADVHASLENGEATSSHDPSEQKEETEEACAEE-ESHREDISEADLVDISAYS-----GIGEDSGGSQLDDDEEAEDDD---AYEPESS---------------------------------------------------------------------------------------------------------------------------------------------------CSEIPGLPAED---------EPPPSRKIRFSVNPIKVFTTYSNEDYDRRNDEVDPMAASAEYELEKRVERLDLFPVELEKDKDGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLIVEVDGTSLVGVTQNFAASVLRNTSGTVKFVIGREKPGEQSEVAQLIQQTLEQER---------------WQREMMEQRYNPYMEEDEE----------TGECATDEEE-EMSPMFPN---AIEVFDLAENEDMLSPVEMDPEKLAHKFKELQIKHAVTQAEIQQLKRKLAHAEQDKLRWRMERAQLEQTVRENKERMEKLEGYWMEAQSLCQAVDEHLKETQTQYQALERKYSKAKRLIKEYQQKEIEYLKKETAQRRAQEETEASHKVETKNLQEKITDLESKVGALKSLEPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ULJ8-1", "uniprot_id": "NEB1_HUMAN", "id": "Q9ULJ8-1", "name": "Neurabin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKTESSGERT-------TLRSASPHRNAYRTEFQALKSTFDKPKSDGEQKTKEGEGSQQSRGRKYGSNVNRIKNLFMQMGMEPNENAAVIAKTRGKGGHSSPQR-----RMKPKEFLEKTDG-SVVKLESSVSERISRFDTMYDGPSY--------SKFTETRKMFERSV-----------------HES-----GQNNRYSPKKEKAGGSEPQDEWGGSKSNRGSTDS-------------------LDSLSSR---TEAVSPTVSQLSAVFENTDSPSAIISEKAENNEYSVTGHYPLNLPSVTVTNLDTFGHLKDSNSWPPSNKRGVDTEDAHKSNATPVPEVASKSTSLASIPGEEIQQSKEPEDS-------------------------------------------TSNQQTPDSID---------------------KDGPEEPCAESKAMPKSEIPSPQSQLLEDAEAN------------------------------------------------------------------------------------------LVGREAAKQQRKELAGG-DFTSPDASASSCGKEVP-EDSNNFDG-SHVYMHSDYNVYRVRSRYNSDWGETGTEQDEEEDSDENSYYQPDME---------------------------------------------------------------------------------------------------------------------------------------------------YSEIVGLPEEE---------EIPANRKIKFSSAPIKVFNTYSNEDYDRRNDEVDPVAASAEYELEKRVEKLELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREKPGQVSEVAQLISQTLEQER---------------RQRELLEQHYAQYDADDDE----------TGEYATDEEEDEVGPVLPGSDMAIEVFELPENEDMFSPSELDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWELEKTQLQQNIEENKERMLKLESYWIEAQTLCHTVNEHLKETQSQYQALEKKYNKAKKLIKDFQQKELDFIKRQEAERKKIEDLEKAHLVEVQGLQVRIRDLEAEVFRLLKQNGTQV-------------------------------NNNNNIF------------------------------------------------------------------------------------ERRTSLGE-----------VSKGDTMENLDGKQTS-------CQDGLSQDLNEAVP-------------ETERLDSKALKTRAQLSVKNRRQRPS----RTRLYDSVSSTDGEDSLER---KNFTFNDDFSPSSTSSADLSGLGAEPKTPGLSQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LALSSDESLDMIDDEILDDGQSPKHSQCQNRAVQEWSVQQVSHWLMSLNLEQYVSEFSAQNITGEQLLQLDGNKLKALGMTASQDRAVVKKKLKEMKMSLEKARKAQEKMEKQREKLRRKEQEQMQRKSKKTEKMTSTTAEGAGEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35867-1", "uniprot_id": "NEB1_RAT", "id": "O35867-1", "name": "Neurabin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKAESSGERT-------TLRSASPHRNAYRTEFQALKSTFDKPKPDGEQKTKEGEGSQQSRGRKYGSNVNRIKNLFMQMGMEPNENAAIIAKTRGKGRPSSPQK-----RMKPKEFVEKTDG-SVVKLESSVSERISRFDTMHDGPSY--------AKFTETRKMFERSG-----------------HES-----GQNNRHSPKKEKAGEAEPQDEWGGSKSNRGSSDS-------------------LDSLSPR---TEAVSPTVSQLSAVFENSESPGAITPGKAENSNYSVTGHYPLNLPSVTVTNLDTFGRLKDSNSRPSSNKQATDTEEPEKSEAVPVPEVAQKGTSLASLPSEERQLSTEAEDV-------------------------------------------TAQPDTPDSTD---------------------KDSPGEPSAESQAMPKSNTLSRPKEPLEDAEAN------------------------------------------------------------------------------------------VVGSEAEQPQRRDLTGGGDLTSPDASASSCGKEVP-EDSNSFEG-SHVYMHSDYNVYRVRSRYNSDWGETGTEQDEGDDSDENNYYQPDME---------------------------------------------------------------------------------------------------------------------------------------------------YSEIVGLPQEE---------EIPANRKIKFSCAPIKVFNTYSNEDYDRRNDDVDPVAASAEYELEKRVEKLELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREKPGQVSEVAQLISQTLEQER---------------RQRELLERHYAQYDADDDE----------TGEYATDEEEDEVGPILPGGDMAIEVFELPENEDMFSPSDLDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWELEKNQLQQNIEENKERMVKLESYWIEAQTLCHTVNEHLKETQSQYQALEKKYNKAKKLIKDFQQKELDFIRRQEVERKKLEEVEKAHLVEVQGLQVRIRDLEAEVFRLLKQNGTQV-------------------------------NNNNNIF------------------------------------------------------------------------------------ERRPSPGE-----------VSKGDTMENVEVKQTS-------CQDGLSQDLNEAVP-------------ETERLDSKALKTRAQLSVKNRRQRPT----RTRLYDSVSSTDGEDSLER---KNFTFNDDFSPSSTSSADLSGLGAEPKTPGLSQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LALSSDESLDMIDDEILDDGQSPKHTQSQSRAVHEWSVQQVSHWLVGLSLDQYVSEFSAQNISGEQLLQLDGNKLKALGMTSSQDRALVKKKLKEMKMSLEKARKAQEKMEKQREKLRRKEQEQMQRKSKKSEKMTSTTEQP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AVP7-1", "uniprot_id": "A0A8M3AVP7_DANRE", "id": "A0A8M3AVP7-1", "name": "Neurabin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKTEASAERN-------TLRSASPHRNAYRAEFQALKKAFDQPRQDGDHKHKDPEGVRQPRGRQYGAHVSRIKNMFMQMGTES------TGSNRQARDETSPQK-----LNKPTNFINRTDG-SVVKFQQGTGERTS------GGHHN--------SKFSETRKLFEQSS-----------------RDA-----SQSPVYSYGRDKRGSHEHLDDWRGARSNRGSTDS-------------------LDSLCSR---TEASSPTVSQLSAVFENIDQQGSGATFRRSHG--SGRGLYSP-------DGLQKHGEASEDD---TSARQ-------SPSSGFYRTRVGSKHNLPVSSSSEDLLSPSPLSEA-------------------------------------------KTDEKKSQEMI---------------------EESGELQLKDEINSTKALNGSSTPAEVNDAAGH------------------------------------------------------------------------------------------LLEATRVHEDT-------DGHVKEESRRITEDQIE-ETNEEYCGNERVVFNADG------DACYQGWGESCTEP-EDDLYDDDLSYDPGSE---------------------------------------------------------------------------------------------------------------------------------------------------ITEIPGLPEEEKE-------DIPQKRKIQFSSAPIKVFKTYCNEDYDRRNEEVDPVASSAEYELEKRVEKLELLPVELEKDDDGLGISIIGMGVGADAGLEKLGIFVKTVIEGGAAERDGRIKVNDQIVEVDGTSLVGVTQSFAASVLRNTQGVVRFVIGRERPGQQSEVAQLISQTLEQEK---------------RQREMMEQQYAQYDADDDE----------TGEYATDEEE-EAGQTGTDRDVAIEVFDLPENEDIISPSEMDATKLFQKFRELQIKHTVTEAEIQKLKSKLAAVEKEKARWEREKTQLKQSIEDNKERMLKLESYWIEAQTLCHTVNEHLKEAQSQYQALEKKYNKAKKLIKDFQQREMEFAQREDTEKKRLEEAEKAHLAEIQSLQVRIATLESELMQLMKQNGIQV-------------------------------NNNNNSA------------------------------------------------------------------------------------ESRAQLTERLMALQCSRRNVAEGDLCELTGASETERDERGSKSQSSRASDATEATIRHLQPHPGPDNEDSSASRDHKSGNKRLDLGSSLRKSKGTDQDPKGSPGKSSTGPSAENSPERRRSKGPGVSDELSLSSSSSTEISGV-----LSGRSRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTLSSDESVDMIEDEIVDEGLPVKPQQWQNRSVTEWTCQQVSCWLMGLNLEQYVSLFTAKNLDGEQLLKLDSTALKALGIESSSDRALIKKKLKDLKVLMEKAR-------RNREKQRKKELEQTRKNSSSSRPAEGATE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PX85-1", "uniprot_id": "A0A8M9PX85_DANRE", "id": "A0A8M9PX85-1", "name": "Neurabin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIKSENKSDRA--------LRSASPHRNAYKSDFHSIKCTFDGSASISATSPFSNGD-GETRGRPSGNKVSKIKNIFLQMDGKQNQDSPNISKPTSPRFPLDSTPYRSSQSSVSSLDSATFETRKTEDVSINKAALAEKFSMTRKLFESGLKEQSPTERSASIKVIWPQPMERPDMKVSVTGEK----KDKTNVIEGQAEERDDKEKEKGESETPPHKLSTSMNAGPISRR------------------LESFMLDSDSESLSAAPSTESHSPISHSQSPSATSDHSDPPSSPDSCSSPTSYSLWADSPSETCFPKLHGSDLHNPPLNGVCMQKTLHNTSSTPEEHVNESPEDTVSSEPTLLFTSEKVHIFSSMTSTSHASEAEDPAFQEQQGEGTSSEKVPGLSTVRAELVVVKTESSESEGNE---------------------EELAEDDVFEEPEMEEQSLNYNSGRILTNSEEHRLTFLGKLCEESVHTGKKEDHRGEGNFLEENIMEQEDDDEEEGKKD--------------NKEVDRKTDRTEEEVVLESVMGEGEQKATDVENKEQQNEQREEEDEEEDGRVEEAVEALEEDEDEREMEDEDLAGKERQQQDDQGLMGNRSLICGIENAAFVDDKDNRTDLECQVKEESEE---------------------------------------------------------------------------------------------------------------------------------------------------FEELPGLSDEE---------NLNPKRKIKFSTAPIKVYFTFSNEDYDRSNDDVDPVSASAEYELEKRVEKMDVVPIDIQKGNDGLGISIIGMGVGADQGLEKLGIFVKTITEGGAAHRDGRVRVNDQIVEVDGISLVGVTQHFAATTLKNTKGLVKFLIGREKPGVESEVARLISETLQHETSPENQEPKDEEHPKPQNNHLQEEKQIYYQHQDQQEIDPLAEKNVVQQDKQKEAEEEQSAEDASSELAQEVFSQLKSQGIDLPEDIDATELEHKFKELQIKHSVTVTELSQLREKLEVSEAERKSWEARGAALERSVEESKERIEKLEKYWLDAQGLCKTINQRLNEAQSQNDSLQLKYNKTITLLQEHQQREAECGRKEAELKRKLEQKEKEYKTSVRQLQYKIACLEGQAGSDQPEESCSP-------------------------------AGESQPSSPTSGSSERNGLSTDDLQSDADWGDVPQTARLDCSVYRAKAKLVQGSQRKRPSRNKLRESAKSSQGQSQSQESVCTQGKPERTNSERRRSYLESLAIPIPTIQFGNNQTHDLRSEGGGDVFVQSQTPQGGSSTQASLSPPKDSSTPQSPSSSQSSSSLFLNLRNRRSKAKERSKSRASRDEESDGSLTRKSKRRFPDFSGIRRSGGKGKKRESITLRGSVGSRGSGELLDESSCNVSPSGSVSSIPSCMPFSWFGDRDKEKDREREKERSASSGSLPRTPSEGYIEDHTNKTSLSWPSLLSHSLDLSL--------------------------------------------------------------------------------SVTGDSVAGSPRSLLAGFLREPRVLGRSHTHTFSSCETLDDVSTPAAKQYMWQNRPLSEWTNQQVCHWLMGMNMEQYIAEFTAKGVDGQHLLSMDSSKLKELGVSSQRDRATIKRRLKDMKKAQEKLEKQQVKKEKERGREKDANNKSRQPTNFESAC------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NFI9-1", "uniprot_id": "M9NFI9_DROME", "id": "M9NFI9-1", "name": "Neurabin-1", "aln": "MEKPMHHAPAPVGKVSQIANIFQRKPIEIQPVEQLSAVAAAHAAAAAAAAAAHHAHVQGAPAVRTESHSARFNNARALFEKLGVESNSNVSSRLLRSGSREDNLCDGSDRSSSRSSDRSQSPPKRRTPFPSGVSLVHNNNNAAIVAQNGVPPEQRLSNSKFIVEPAAQVVPTSVVKYPQHNISRLKSEEPSPVPPPASGSVSALFASSGGDKPEKPERKFNSRELIEKQKKWTSHFTKTKTTRTHSDLNRCDIIRTVPGTGLIMDSEKVAKPAMEPPQPPPNASPNPPMRAQAPPEIKPRSGKIGSPVKSPPLPPIPAVKPKNVSPVKFNPDRLRQSPTKTADNSPPPPPAKSAAVLQRSLMQEQQELLRNSCDQGVAPIPPEKPRKKSVDLIEDTLPLTNCSTPSSCASPTSSYLMQPAKRGSLDGGSGNGQYPGNGLSGSTNSATSGSPVASASSGPSSPVHTEDEKQENESTEKSEMEYYHGGNYNSVPRRRRSENEGRKSVDESSPSANNSQQQQQHSIPGSAAGSPQRVANKRSSITVNMPAAGLGQRPPSIISTTSQDEGGFNESAPELKAKLQPAYDQTEEQPHSLNYVDVGYRLNPDGSESREVYGSEAELYDTAKVTDMQRKFHGANGFGQESSTVYAIIKPDVQESQPVAPSRSVLIQSPNSSSVEGSPLHRGSYSSPPVGVVSPIRRRNSSNQDQSVGGGGSAKTTPQCSPARSALVKGIAPIASIDAHEEEELDLVEEDEHLAVEYVEVLELQQDEEEEEAPVLPERRAPAQGSLELQDLEYADTSAGEDEEDIINHLKDGDVLDVELIDDVVDEVIKVHVNHSVATAPSIQAATPAAAIPREDSLPDDMTAAEAERLLSSSILENKIRQQSLLSDEQAKEVEQILNAAPSVGVAVATVVATATSPTSIKNLIEDLPGQSAVAASAANGEQDIQIAAVPAIVEEDEDEEEDFPEDDEEDHARADFDANGGDADGDSDDVEAVDIVGYGHASTALNATFVKADSTETETTTTTPSTATTATTRHDDDEPEWLRDVLEAPKRSLENLLITSATSSRAPGQREELENGYDLHEKHSDLNQTYITGGESLHESIVSVESTQSDATLNQTTTIDDSIISSKHNSTYSLADAEQATSSTVLSTGVTELDDSQYYIPEYPPVRSKEVLVEAGVHYFEDGNFWMEVPGLLDFDDDDCSYPPITVRKNPKVRFSSGPIHVYSTFSVNDYDRRNEDVDPVAASAEYELEKRVEKMHVFPVELMKGPEGLGLSIIGMGVGADAGLEKLGIFVKTITDNGAAARDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGLVKFQIGRERDPENSEVAQLIRLSLQADR---------------EKEERLKRQQEEYLRRTLD--------------YSEDSTQPVSANSSVCEGPSSPVQVEHPMEVEATHSQEVESLKRLLQESEMGCLVKEEIIQNLKRKLVKLETTGNENELLSERLRQSERELG-----------NIRKEAANLQNMLQQSQGQYMALDKKYNKAKRLVREYQQRELDMCHREEFYQQLLQEKDTEYNALVKKLKDRVINLEHELQETQRKAGFPVGLPYDSATLKLTPQMMRKTPPKPLFHKLETELSDTEISDLSPDGDGVKTATVERKVPVKDELDAAVPQHELLDNSINKTKIDLASRGGLANRQLPSANGNSSTSNGAAVDLGQLSNGNLLKRSRSNSRSSDCTLDDTDEEEEREGSALNLAGAPVAHETISLSNGNSHLLANVNNLLQHHPPAMATVIATPSNGHLGTTTPILLNSTSSASSSSSNQSTAREAQINQLYAQVHKDPSKQQHQQQQQQQQQAQAVTTSIPSIFKNALGSPADNGLNDFHRGSMTTFGTGPATSSNRDLNSSYDSILGSNDKLAENDPAESWMYPSRRRVAPNGSKVPLPGSSFTDQLNQALSDRERRLGDGSSRHSSDDYTEINKSQSAAAINCKTLINEIRQAVNEAQPKVKQVVPQSLSPPGTVPWQQQHHQQIQQQPSAHTTGPPSPTSMSSGCSSPGYSPSRTLDLSGSSSSFSDRKAMAAGYTYKGGPVHEWTKDQVGHWLMGIELERYIPVFKENNVEGGALLTLDSKDFKTLGICGD-DKHRLKKRLKDLKANIEKERKDMERERREREKAIRKAEKKAAKKK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..*. .. . : . . : . . . . : : . . . * . . : . :. : . ... : . . : : : . . *: ** : . *::** **:*: *:. :**** *::***:::***********::.:.*::: *. :***:******.*** ***********: :.*** ****::*** ::**** ******* :**:.*:**.* *:* ****: ****:** :*: : :.. :.: * : .: . . . . .. . . . : .* : ::* :: *. :.:*: ** * . *.:. .: : : . ::: *.::* * :*: **.*: *:::.**:* : ::: :: :: : * :: ** : ", "identical_positions": 119, "similar_positions": 151, "identity": "5.39%" }, { "cls_id": "homologset.agr.FB:FBgn0010909", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LP90-1", "uniprot_id": "MINK1_RAT", "id": "F1LP90-1", "name": "Misshapen-like kinase 1", "aln": "MGDP-------APARQSDFIFLVALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHG-EEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIE----------EQKEERRRVEEQQRREREQ-RKLQEKEQQRRLEDMQA---------------LRREEERRQAEREQEYKRKQLEE-QRQSERLQRQLQQEHAYLN-----------------SQKQQQQQQQQQ-QQQQQQQILP--------------------------------GDRKP-LYHYGRGINPADKPAWAREVEE----------------------------------------------------------------------------------------------------------------------RARMN-------KQQNSPLAKTKPSSAGPEPPIPQASPSPPGP--LSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAAVPTPTATPSARGAVIRQNSDPTSEGPGPSPNPP--------------SWVR-PDNEAPP------KVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNS----AWQIYLQRRAERGTPKPPGPPAQPPGPPNTSSNPDLR-RSDPGWERSDSVLPASHG------HLPQAGSLERNRNRVGASTKLDSSPVLSPGN-KAKPEDHR--SRPGRPA--------DFVLLKERTLDEA------------PKPPKKAMDYSSSSEEVESSEDEEEEGDGEPSEGSRDTPGGRSDGDTDSVSTMVVHDVE-------EVSGTQPS----YGGGTMVVQRTPEEERSLLLADSNGYTN----LPDVVQPSHSPTENSQGQSPPTKDGGGDYQSRGLVKAPG--KSSFTMFVDLGIYQP-GGSGDTIPI----TALVGGEGGRLDQ-----LQFDVR------------------KGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIVFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM52-1", "uniprot_id": "MINK1_MOUSE", "id": "Q9JM52-1", "name": "Misshapen-like kinase 1", "aln": "MGDP-------APARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHG-EEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIE----------EQKEERRRVEEQQRREREQ-RKLQEKEQQRRLEDMQA---------------LRREEERRQAEREQEYKRKQLEE-QRQSERLQRQLQQEHAYLK-----------------SLQQQQQQQQLQKQQQQQQQILP--------------------------------GDRKP-LYHYGRGINPADKPAWAREVEE----------------------------------------------------------------------------------------------------------------------RARMN-------KQQNSPLAKAKPSSAGPEPPISQASPSPPGP--LSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAAVPTPTATPSARGAVIRQNSDPTSEGPGPSPNPP--------------SWVR-PDNEAPP------KVPQRTSSIATALNTSGAGGSRPAQAVRA-----------------------------------------SNPDLR-RSDPGWERSDSVLPASHG------HLPQAGSLERNRNRVGASTKLDSSPVLSPGN-KAKPEDHR--SRPGRPASYKRAIGEDFVLLKERTLDEA------------PKPPKKAMDYSSSSEEVESSEEEEEEGDGEPSEGSRDTPGGRSDGDTDSVSTMVVHDVE-------EISGTQPS----YGGGTMVVQRTPEEERSLLLADSNGYTN----LPDVVQPSHSPTENSKGQSPPTKDGGSDYQSRGLVKAPG--KSSFTMFVDLGIYQP-GGSGDTIPI----TALVGGEGGRLDQ-----LQFDVR------------------KGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4C8-1", "uniprot_id": "MINK1_HUMAN", "id": "Q8N4C8-1", "name": "Misshapen-like kinase 1", "aln": "MGDP-------APARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHG-EEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIE----------EQKEERRRVEEQQRREREQ-RKLQEKEQQRRLEDMQA---------------LRREEERRQAEREQEYKRKQLEE-QRQSERLQRQLQQEHAYLK-----------------SLQQQQQQQQLQ--KQQQQQLLP--------------------------------GDRKP-LYHYGRGMNPADKPAWAREVEE----------------------------------------------------------------------------------------------------------------------RTRMN-------KQQNSPLAKSKPGSTGPEPPIPQASPGPPGP--LSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDP-AIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPP--------------AWVR-PDNEAPP------KVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNS----AWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLR-RSDPGWERSDSVLPASHG------HLPQAGSLERNR--VGVSSKPDSSPVLSPGN-KAKPDDHR--SRPGRPA--------DFVLLKERTLDEA------------PRPPKKAMDYSSSSEEVESSEDDEEEGEGGPAEGSRDTPGGRSDGDTDSVSTMVVHDVE-------EITGTQPP----YGGGTMVVQRTPEEERNLLHADSNGYTN----LPDVVQPSHSPTENSKGQSPPSKDGSGDYQSRGLVKAPG--KSSFTMFVDLGIYQP-GGSGDSIPI----TALVGGEGTRLDQ-----LQYDVR------------------KGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDG2-1", "uniprot_id": "A0A8M9QDG2_DANRE", "id": "A0A8M9QDG2-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSEN-------APTRSLDDIDLAALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEEEEEEIKAEINMLKKYSHHRNIATYYGAFVKKSPPGHDDQLWLVMEFCGAGSVTDLVKNTKGNSLKEDWIAYICREILRGLSHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDSTYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFIDFIEGCLVKSYPNRPSTEQLLKHSFIRDQPTERQVRIQLKDHIDRTRKKRGEKEETEYEYSGSDEEDENRG-DERESSSILNVPGESTLRRDFLRLQQENKERSEALKRQQAQLAAQRRDPEEHKRQLLHDRQKRIE----------EQKEQRRRLEEQQRKEREMVRQQQDKAPHRRLDDMR------------------REEDRRLAEREQEFIRHKLEEEQRQLEILQQQLLQEQALLMLYNKHCSDSSVNEYKRKQLEEQRQSERLQRQLQQEHAYLVSL-QQQQQQ-----------------------QDKKPQMYHYSKNLE-NNKPAWAREVEE----------------------------------------------------------------------------------------------------------------------RSKLN-------RQGSPKICTTVSDTN----IQSRSESINQSG--AAQTPPMQRPVEPQGGQGKFQMAHLVPLKPYAAPVPRSQSLCDQPTKTMSAFPT-QDPSP----TPTPRPLHSRELVRQNSDPTSETPAPQSRPMRDDR---------GPWIRLPEIEQPP------KIPQRTASIATALNTNLSSGIR--HPVRA-----------------------------------------SNPDLS-RNE-RWERGDSMSIMSN--------LPQTGSLERHR--ILSSSKMDSSPTLSHDG-RHKPGESRTSSRPSRPASYKRAIGEDHGLYSKERAEEQ------------PRPPVKANDYSSSSESSESSE-ESESGEGAEEESPTDRP---RDADSDSVNTMVVHEEE-------EGEGGEEERAGGYGDQTMLVQRTPEKR------SHNGYTN----LPDVVQPSHSPTDSAS-HSSPGKDSTYDYQSRGLVKASG--KSSFTTFVDLGMYQPSGGSGDNIS--------VGGLGSRFEQ-----LKLEVR------------------KGSMVNVNPTNTRPVSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLKLLDRSGQGKVYPLINSRRFQQMDVLEGLNLLITISGKKNKVRVYYLAWLRNKILHND---PEVEKKQGWTTVGEMEGCVHYKVVKYERIKFLVIALKNAVEVYAWAPKPYHKFMAFKSFGDLPHRPVLVDLTVEEGQRLKVIYGSLAGFHAIDVDSGNNYDIYIPVHIQSQITPHAIVFLPNSDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAHICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K490-1", "uniprot_id": "A0A0G2K490_RAT", "id": "A0A0G2K490-1", "name": "non-specific serine/threonine protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHGQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN--DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLE--QQQRENEEHKRQLLAERQKRIE----------EQKEQRRRLEEQQRREKEL-RKQQEREQRRHYEE-----------------QMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLL------------EYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQ----------------------RPLEKKPLYHYKEGMSPSEKPAWAKEVEE----------------------------------------------------------------------------------------------------------------------RSRLN-------RQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRP-------VDPQIPQLVAVKSQGPALTASQSVHEQPTKGLSGFQEALN-----------VTSHRVEMPRQNSDPTSENPPLPTRIEKFD----------RSSWLRQEEDIPP------KVPQRTTSISPALARKNSPGNGS-ALGPRLGS----------------------QPIRASNPDLRRTEPVLESSLQ-RTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTR--VRANSKSEGSPVLPHEPSKVKPEESRDIPRPSRPASYKKAIDEDLTALAKELRELR--------IEETNRPLKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGKNEQYNMGMVGTHGLETSHADTFGGSISREGTLMIRETAEEKKRSGHSDSNGFAGHIN-LPDLVQQSHSPAGTPTEGLGRVSTHSQEMDTGAEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDDESSAAALFTSELLRQEQ----AKLNEAR------------------KISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83510-1", "uniprot_id": "TNIK_MOUSE", "id": "P83510-1", "name": "Traf2 and NCK-interacting protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN--DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLE--QQQRENEEHKRQLLAERQKRIE----------EQKEQRRRLEEQQRREKEL-RKQQEREQRRHYEE-----------------QMRREEERRRAEHEQEYKR-----------------------------------------KQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQ----------------------RPLEKKPLYHYKEGMSPSEKPAWAKEVEE----------------------------------------------------------------------------------------------------------------------RSRLN-------RQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRP-------VDPQIPQLVAVKSQGPALTASQSVHEQPTKGLSGFQEALN-----------VTSHRVEMPRQNSDPTSENPPLPTRIEKFD----------RSSWLRQEEDIPP------KVPQRTTSISPALARKNSPGNGS-ALGPRLGS----------------------QPIRASNPDLRRTEPVLESSLQ-RTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERSR--VRANSKSEGSPVLPHEPSKVKPEESRDITRPSRPA--------DLTALAKELRELR--------IEETNRPLKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGNNEQYNMGMVGTHGLETSHADTFGGSISREGTLMIRETAEEKKRSGHSDSNGFAGHIN-LPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGAEYGIGSSTKASFTPFVDPRVYQTSPTDEDEEDDESSAAALFTSELLRQEQ----AKLNEAR------------------KISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKE5-1", "uniprot_id": "TNIK_HUMAN", "id": "Q9UKE5-1", "name": "TRAF2 and NCK-interacting protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN--DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLE--QQQRENEEHKRQLLAERQKRIE----------EQKEQRRRLEEQQRREKEL-RKQQEREQRRHYEE-----------------QMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLL------------EYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQ----------------------RPVEKKPLYHYKEGMSPSEKPAWAKEVEE----------------------------------------------------------------------------------------------------------------------RSRLN-------RQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRP-------VDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALN-----------VTSHRVEMPRQNSDPTSENPPLPTRIEKFD----------RSSWLRQEEDIPP------KVPQRTTSISPALARKNSPGNGS-ALGPRLGS----------------------QPIRASNPDLRRTEPILESPLQ-RTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTR--VRANSKSEGSPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELR--------IEETNRPMKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISREGTLMIRETSGEKKRSGHSDSNGFAGHIN-LPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQ----AKLNEAR------------------KISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA19-1", "uniprot_id": "A0A8M2BA19_DANRE", "id": "A0A8M2BA19-1", "name": "non-specific serine/threonine protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKAEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEEWTAYICREILRGLTHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHNQRPSTEQLIKHPFIKDLPNERQVRIQLKDHIDRTKKKRGERDETEYEYSGSEEEEEER--DIGEPSSIINIPGESTLRRDFLRLQLANKERSEALRRQQLE--QQQ--NEEHKRQLLAERQKRIE----------EQKEQRRRLEEQQRREREL-RKQQEREQRRRYEEM---------------EQLRREEERRHAEREQEYIRRQLEEEQRQLEILQQQLLQEQALLL------------EYKRKQLEEQRQAERLQRQLQQERAYLVSLQQQQQEP----------------------RPADKKQLYHYKDSVNPSDKPAWAKEVMERAQSNSPRIPPKKHHSFNSPGDKRVGQFLAHDQNPSNQPTRPPSYPASSHSREMDLAEPQLRIVSGPNVPRIRVSCEPDPSQLARMVQQHLEQESRGHNRSSKGAEIERDLYVSKVEERSKLN-------RQSSPALQHKVANRISDPSLPPRSESFSSGGIQQARTPPMHRS-------VEPQMAHLVSVKSHGSSMTGSQSLHDQSSQGVSAFQEGL-------------SPHRPPMPRQNSDPTSETPAPPPRITSRDD---------RGSWLRQEEDVPP------KVPQRTTSISPALVRKNSPGNGPGGLGPRTGA----------------------HLIRASNPDLR---IPVEPSLQ-RTSSGSSSSSSTPSSQ------------GGSSERNR--LGGSNKPEGSPAVSQEPKAKTQEENREVTRPSRPA--------DLTALAKELRELRT-------NEDTNRPPRKVTEYSSSSEDSESSEEE--DGEGGAHDGTVPVSDIPRIMPSAGQGGTDSLGN-------QEDSHSNDSFGKNSQDSTLMMRETFGERK-LGHAESNGFPGSSN-LPDLVQQSHSPA----EGPGRQSS-ALDLDSVAEFGMG---KASFTPFVDPRVYQTSPTEDDEDN---PASALFADELLRQEQEQEQARLNEAR------------------KISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCVHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFTDLQHKPLLVDLTVEEGQRLKVIYGSSVGFHVIDVDSGNPYDIYIPSHIQGSVTPHAIVVLPKTDGMEMLLCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLSERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BAL6-1", "uniprot_id": "A0A8M2BAL6_DANRE", "id": "A0A8M2BAL6-1", "name": "non-specific serine/threonine protein kinase", "aln": "MASD-------SPARSLDEIDLSTLRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKCMDVTGEEEEEIKAEINMLKKYSHHRNIATYYGAFIKKNPPGVDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEDWTAYISREILRGLTHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVSRRNTFIGTPYWMAPEVIACDENPDATYDYKSDLWSLGITALEMAEGAPPLCELHPMRALFLIPRNAPPRLKSKKWTKRFHSFIESCLVKNHNMRPGTDQLLKHPFIRDMANERTIRIQLKDHIDRTRKKRGERDETEYEYSGSEEEEEAML-EIGEPSSIINIPGESTLRRDFLRLQVANKERSDALRRQQLE--QQQ--NEGHKHQLLAERQKRIE----------EQKEQRRRLEEQQRREREA-RKQQE--QRHRYEE------------------LRREEERRQAEREQEYIRRQLEEEQRQLEILQQQLLQEQALLL------------EYKRKQVEEQRQADRLQRQLQQERAYLVSLQQQQQQQQQD------------------SRPEEKKQLYHYKDAVNPSDKPAWAKKIHGPPQIKIQPSNRKQSTPLYYKLDNLGIPIGRAILNPSIN-------------------------------QSVMQPLKPQKQNLIQRQSISPPPQYSAKKISMGPRPGFSRPPYKRVEERSKLN-------RQSSPALQHKVANRISDPSLPPRSESFSSGGMQPARTPPMHRP-------VEPQMAHLVPVRSHSSSMSVSQSLHDQSAKGVSAFQESL-------------VSNRPEMPRQNSDPTSEMPPPAPRMASHEEK------PDRSSPWLREDAVPPKLSGTTQVPQRTTSISPALARKNSPGNGESSGGGRSAS----------------------QLIRTSNPDLRRTELSLDVALQ-RTSSNSSSSSSTPSSQG--------GSQPGSSERNQ--PRGSGKSEGSPVALQETSKPIQEEGRELSKPSRPA--------DLTALAKELRELR--------IDEVSRPPLKLTDYSSSSEDSDSSEDE--DGTVG-HDGTVSVSDIPRIMPS-VQGNNESFTSS------HDDSLTDSYNDE-SKDGTLRMREN-NERQRLGHGESNGFAGHGN-LPDLLQQSHSPSGTP-TGLN-----SQDLDSMDEFGLGGGSKASFTPFVDPRVYQTSPTDDNDES---SAAAMFANELLRQEQ----AKLNEAR------------------KISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLITRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGELEGCIHYKVVKYERIKFLVIALKNSVEIYAWAPKPYHKFMAFKSFTELQHRPQLVDLTVEEGQRLKVIYGSSVGFHVIDVDSGSPYDIYIPSHIQSTVTPHAIVVLPKTDGMEMLLCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSLMNW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M754-1", "uniprot_id": "F1M754_RAT", "id": "F1M754-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAND-------SPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE----------QQKEQRRRLEEQQRREREA-RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEDEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLL------------ECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRP---------------------HAQQ--PPPPQQQDRSKPSYHAPEPKPHYDP-------------------------------------------------------------------------------------------------------------------ADRAREVEDRFRKTNHSSPEAQAKQTGRGLEPPVPSRSESFSNGNSESVHPALQRPAE------PQVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDP----------CPPSRSEGLSQSSDSKSEVPEPTQKAWSRSD----------------SDEVPP------RVPVRTTSRSPVLSRRDSPLQGSGQQNSQAG-----------------------QRNSTSSIEPRLLWERVEKLVP-RPGSGSSSGSSNSGSQP----GSHPGSQSGSGERFR--VRSSSKSEGSPSQRLENAAKKPEDKKEVFRPLKPAV-----RIDLTALAKELRAVE-----------DVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSLNLSNGETESVK---TMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSS--------------------------------------------------SSFTPFIDPRLLQISPSSGTTVT----SVVGFSCDGLRPEA----IRQDPTR------------------KGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCTIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97820-1", "uniprot_id": "M4K4_MOUSE", "id": "P97820-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 4", "aln": "MAND-------SPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKT-VTAAIKVMDVTEDEEEEITLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGGPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE----------QQKEQRRRLEEQQRREREA-RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLL-------------------------------------------HDHRRP---------------------HAQQQ-PPPPQQQDRSKPSFHAPEPKPHYDP-------------------------------------------------------------------------------------------------------------------ADRAR------------------------------------------------------------EVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDP----------CPPSRSEGLSQSSDSKSEVPEPTQKAWSRSD----------------SDEVPP------RVPVRTTSRSPVLSRRDSPLQGGGQQNSQAG-----------------------QRNSTSSIEPRLLWERVEKLVP-RPGSGSSSGSSNSGSQP----GSHPGSQSGSGERFR--VRSSSKSEGSPSPRQESAAKKPDDKKEVFRSLKPAG-----EVDLTALAKELRAVE-----------DVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSPNLSNGETESVK---TMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSS--------------------------------------------------SSFTPFIDPRLLQISPSSGTTVT----SVVGFSCDGLRPEA----IRQDPTR------------------KGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELLHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCGRNDKVFFSSVRSGGSSQVYFMTLGRTSLLSW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95819-1", "uniprot_id": "M4K4_HUMAN", "id": "O95819-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 4", "aln": "MAND-------SPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE----------QQKEQRRRLEEQQRREREA-RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLL------------ECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRP---------------------HPQHSQQPPPPQQERSKPSFHAPEPKAHYEP-------------------------------------------------------------------------------------------------------------------ADRAR--------------------------------------------------------------EVEDRFRKTNHSSPEAQSKQTG-----------RVLEP----------PVPSRSESFSNGN------SESVHPALQRP--------------------AEP------QVPVRTTSRSPVLSRRDSPLQGSGQQNSQAG-----------------------QRNSTS-IEPRLLWERVEKLVP-RPGSGSSSGSSNSGSQP----GSHPGSQSGSGERFR--VRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPA--------DLTALAKELRAVE-----------DVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVK---TMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSS--------------------------------------------------SSFTPFIDPRLLQISPSSGTTVT----SVVGFSCDGMRPEA----IRQDPTR------------------KGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8F4-1", "uniprot_id": "A0A8M3B8F4_DANRE", "id": "A0A8M3B8F4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MARD-------FTTTSLSNIDLASLRDPAGIFELIEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEDEIKLEINMLKTHSHHRNIATYYGAFVKKSPAGQDDQLWLVMEYCGAGSVTDLLKKTKGNCLKEDWIAYVCREVLRGLLHLHSHHVIHRDIKGQNVLLTENAEIKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDSTYDYRSDVWSLGITALEMAEGVPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFQTFVDSCLVKNYLHRPSTETLLRHSFIKDLPNERQVRITLKDHLDRTRKRRQEKDGKEYEYSGSEDEDDGINEEEGEPSSIVNLPGESMLRREFLRLQQETNSQTQLIQQVHNQ--------DNYKKQLLADRQKRIQ----------QQQEERRRFEDHQER-----LLHETGVQWPELQE------------------MLWQEETDLTEKSKRNHKKQPKD----SEHHRTDVESASSNLF-------------------DEQAQGRKAQRTLPRDQSQLLFLLHDHTHQ---------------------------------QKSSRATPHDGLAGKLES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LETHLVNLNNLAVRIPHVQSRLGSGSNSSPCTPALQRAVK--------QPNMNVCSSQEIHHSSSMSDVNAPLSPTLDD------------VFFTPDDQPP------KIPERTTSKFKDVMGHHRYGSSGDRQSAMDN--------------------------------------AVKMSFS-NSSTSSSQSGYCVLDNPAHP---NRNSQSPGASPHN--QGLGTKSQFSPLMKLAEYSSSSDEDDEKMRSPSSN--------GRPVFSRGQTNEI-----------ILQPHLNVKQQQQS--AAKPTHNVYQRPCGSQSSDNYHLPDLLHKSPTHELSYHQTPTQS-------------------SRDKLLNNQPGKSVSSSS--------------------------------------------------------SSFSAFIDPRLLQISPPLSPQGH---------GQLNGRCEP----CVRQPHR------------------KGSVVNVNPTNIRPQSDAPEIRKYKKKFNAEILCASLWGVNLLVGTENGLWLLDRSGQGKVYSLISRRRFQQMDVLEGLNVLITISGKKNKLRLYYLSWLRNKILHND---PEVEKKQGWTSVGDLEGCVSYKVVRYEKIKFLVIALRNAVEVYAWAPKPYHKFMAFKSFSSLPQKPLSVDLTVENGQRLKVIYGSHNGFHAIDVDSGTPFDLYLPSHIQGLIRPHAIIILPSSSGMELLLCYEDEGVYIDTYGRITKETVLQWGEMPASVAYLQANQVMGWGEKAIELRSAKTGSLEGVFMHKKAQKLKFLCERNDKVFFASVQSGGSSQIYFMTLGQNSLFSW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W002-1", "uniprot_id": "Q9W002_DROME", "id": "Q9W002-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQ-LAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGP---------------PARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQ-------NNFKPSLPPRRPEPQPQTAAGGQGSQQQAQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLGQPVNPLDPLDSSDSDSEPDEP-------------------------------------------------------------------------------------------------------------------NDRARNDG----TLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDD------DQAGDRTLIMKRKLEQNINRLQKSASTSQANVTPSRRGDESNLLRDWDFDRFFPKNANGPRGSGRGSPTTTASLSRSSQLSTLKVDTKLQRASVAEAITRPVPRGYQPLKAEPSASQSIAKEQGSASGSGSGSGSASGSGSGGSTNSPAHKRQDSDSRLPTNFERGFRRENSDFFPLAKRYSAVFSGASASGSTAGSPSAQALQRSSAVYQRNSIYSSSISSKSKENDVPGAPGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFLRPRREKTESVIVLQNAAVRAQRLQQLQQQQQQQQLQQQQQQQNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHDKSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTPCSSTSSASISNPLPPHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * * :*:********:*:**************.** **** **** :**:**. ***:**.:*:***********:**.*.* *********:*****:***:*.***: ***: **:.**:**** :** ::**************:***:**************:.************************:*** :**:** ****:****. ****::************..*:******:*:* *:: *:* : ** *: *::. **:* ..:* :** ****:** :*:: *:: :*.****::::: * ***:: ** . ***:* ::* : :: : : *:: : . :: :: :: . . :: : . . . :. * : * . . .. . . :. . . : : : ... . . : : : : : . * . ***.**. .. .::********:**:*****:*******:***.** *********** ** ******:**** *:*:*****::::*:***:**:.:**:.* :**:::** .**:::*. :::*:**:********:.::*:***************.* .* ::* ****:*: .*****:** ***.:*:**. :*:*:* * * : **.*: **.:.**::*:**::****::* **: *: ********:***:: :.* ****:****:**.::* *:******:**:****. *******:*.:...*.*::****.: : .*", "identical_positions": 432, "similar_positions": 230, "identity": "26.15%" }, { "cls_id": "homologset.agr.FB:FBgn0010926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Z9-1", "uniprot_id": "A0A0G2K0Z9_RAT", "id": "A0A0G2K0Z9-1", "name": "", "aln": "------------------MGKAKRTGARRQVHKAPAGAFG--------GPGKTNPNPFEVKVNRQKFQ---ILGRKTRHDVGLPGVSRARAIKKRTQTLLKEYKERNKSNVFTDKRFGEYNSNISPEEKMMKR----FALEQQRYHEKKNIYNLNEDEE-LTHYGQSLADIEKHNDIVDSDSDTEDRGALSAELTASHFGGG--VHKNSSQKEGEDGDKPKTRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILLSRKSKKSENKEKKEKPQPDAYDMMVRELGFEMKAQPSNRMKTEEELAKEEQEKLRKLEAERLRRMLG---KDEHENKKKPKHTSADDLNDGFILDKDDRRLLSYKDGKMNIED-AQEEQSKGADGQENDQKEEEDESEEEGEDGESCEDPDESDGPDSHSDLESSAETEEEDETPKKEQRQTPGGKSPKEAQKAQKAAAAELPYVFAAPESFEELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGNKAKLEKLFGFLLQYIGDLATDSTPD-----LKTIDKLVVHLYNLCQMFPESASDAIRFVLRDAMHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALICMSQMLTKCPVTSLRDVVKGLFVCCLFLEYVSLSRRFVPELLNFLLGILYIATPNKKSQGSTLVHPFRALGKNSELLVVSDKADVTTWQRGSLPLHWANRQSTLTATEANHTRLSCVASCLSLLKHCVLMYSALPSFHAIVTPHQALLAEHLAR-SLPQELQELSRSILSEVESQKQHCPPLICEKSKPVPLKQFTPRLVKVLEFGRK-QGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEVD----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R3N1-1", "uniprot_id": "NOP14_MOUSE", "id": "Q8R3N1-1", "name": "Nucleolar protein 14", "aln": "------------------MGKAKRTGARRQVHKAPAGASG--------GPAKTNPNPFEVKVNRQKFQ---ILGRKTRHDVGLPGVSRARAIRKRTQTLLKEYKERNKSNVFADKRFGEYNSNISPEEKMMKR----FALEQQRYHEKKNIYNLNEDEE-LTHYGQSLADIEKHNDIVDSDSDTEDRGALSAELTASHFGGG--VHKNSSQKEGEDGDKPKTRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILMSRKPKKSEDKEKKEKPQPDEYDMMVRELGFEMKAQPSNRMKTEEELAKEEQERLKKLEAERLRRMLG---KDEHENKKKPKHTSADDLNDGFILDKDDRRLLSYKDGKMNIED-VQEEQSKEADGQENDQKEGEDDSEEEDE---SHEDSEESEDPDSHSDLESNIESEEENETPKKEQRQTPGGKLPKDDQKAQKAVAAELPYVFAAPESFEELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGNKAKLEKLFGFLLQYIGDLATDSTPD-----LKTIDKLVVHLYSLCQMFPESASDSIRFVLRDAMHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALLCMSQMLTKCPVMSLQDVIKGLFVCCLFLEYVSLSRRFIPELFNFLLGILYIATPNTKSQGSTLVHPFRALGKNSELLVVSDKADVTTWQRGSLPLHWANRLSTLTATEANHTRLSCVASCLSLMKHCVLMYQALPSFHAIFRPHQALLSKHLADCSLPQELQELAQSILSAMEGQKQHCRPLVCEKSKPVPLKQFTPRLVKVLEFGRK-QGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78316-1", "uniprot_id": "NOP14_HUMAN", "id": "P78316-1", "name": "Nucleolar protein 14", "aln": "------------------MAKAKKVGARRKASGAPAGARG--------GPAKANSNPFEVKVNRQKFQ---ILGRKTRHDVGLPGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMSPEEKMMKR----FALEQQRHHEKKSIYNLNEDEE-LTHYGQSLADIEKHNDIVDSDSDAEDRGTLSAELTAAHFGGGGGLLHKKTQQEGEEREKPKSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLSHKTPKSENRDKKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEAELAKEEQEHLRKLEAERLRRMLG---KDEDENVKKPKHMSADDLNDGFVLDKDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEGDSSGG---------EDTEESDSPDSHLDLESNVESEEENEKPAKEQRQTPGKGLISGKERAGKATRDELPYTFAAPESYEELRSLLLGRSMEEQLLVVERIQKCNHPSLAEGNKAKLEKLFGFLLEYVGDLATDDPPD-----LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMHEMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQLLTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILYIATPNKASQGSTLVHPFRALGKNSELLVVSAREDVATWQQSSLSLRWASRLRAPTSTEANHIRLSCLAVGLALLKRCVLMYGSLPSFHAIMGPLQALLTDHLADCSHPQELQELCQSTLTEMESQKQLCRPLTCEKSKPVPLKLFTPRLVKVLEFGRK-QGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEJ2-1", "uniprot_id": "NOP14_DROME", "id": "Q9VEJ2-1", "name": "Nucleolar protein 14 homolog", "aln": "-----------------MVAKGKKASADAVYAKKTTRSANPFDN--STAQSSKRGNPFDVHVNKEKFK---ILGRICKHDRGMPGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIGKHLSGDQLTESVMNARYLAEKMSQVRSNQKAEKFNLNDDEL-LTHRGQTLEEIEQYRDERSDDEELDDEALDADFTAAAHFGGE--------------GDSAQDRQAAIDEMIVEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVAKVTKD----EQDAKPPPDAYDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLENERLRRMRADGEEDEEASVAKPKHRSADDLDDGYFLAGEDDEGDDTLAYDLDGNLGTHLNGKKEAVLKGDENEDDDDKEGEEE------EEEDSDEESDSEVDNLSDLK-ESESESEPEEAPKASKKKAKKSADTIPASLDTSIPFTIKMPKTYEDFTELLSKHATAQKAIIIERIIKCNHPKLEGVNRENVVKLYSFLLQYLKDLFEDASEQDIREHFQLLSKLMPYLYELTQLNPERMSNTLLEVIKEKYEEFR-----KNHKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFIQHVLSRSRVRTRQEISMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVHMSIPKRDVEQLEITPPFERDGPLSKLLALPANTESTKLEPQQLQP-----TDLVTQTITPDFKVRALDTSLLLIKEALQLVEEHVGACYLAQPFLALLSRLPLESYPEHVHQHHKDATELAEKLAAQKMKPLAPAEKKPKALRLLEPRFEAVYDDKRR-PKMSKAKEERAKLLHKIKREKKGAIREIRRDTSFVQMLRLKQTLQSDKERHEKVKRIYQEASVQQGELNELSRAKKKKKF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99207-1", "uniprot_id": "NOP14_YEAST", "id": "Q99207-1", "name": "Nucleolar complex protein 14", "aln": "MAGSQLKNLKAALKARGLTGQTNVKSKNKKNSKRQAKEYDREEKKKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGKPGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRFGERDKLLTEEEKMLER---FTRERQSQSKRNANLFNLEDDEDDGDMFGDGLTHLGQSLSLEDELANDEEDFLASKRFNEDDAELQ-------------QPQRKKTKAEVMKEVIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPKKNPMEPKTDLD-KEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELEQQRLDRMNG------MIELEEGEERGVEDLDDGFWENEEDYE-----------------------------------------------DDNDGIADSDDDIKFEDQGRDEGFSQILKKKN------------------------ISISCPRTHDALLDQVKKLDLDDHPKIVKNIIKAYQPKLAEGNKEKLGKFTAVLLRHIIFLSNQNYLKN----VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDALSNGD-LVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVEKENQ--EKPLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMDTEAHPVDQCVSV-LLNVMESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYSDFEKPRNILNKVEKLTKFT--EHIPLALQNHKPVSIPTHAPKYEENFNPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNKYERERKLRGGKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . : . . . ***:::. ::* : : * **:*: . .:* ::: . :.* . . *:*:*: . *.::: * : :.: . :**::** *: * .: : . .. : :: : . : : : :.*:*.:.* *.* : : ::** ::: : : . : . . . ** ::*: :: :. ::: . * : : .:** :** ** . . : :. ..:**:**: :* . :: : .*.. . .. . * .: :: : *.:.: : : :: :::.* *. :*.* *: :: *: ..**.:: * : . . :.: * : : .* . : :: .*:. : .. * *:::.: . *:.*** * *:**.:: :.:.* : . : : : * .: :. :: *:* :* :. *: *: : : *. * * :. : :. . : : . : : * : . : * **: . :. : ** : ** .: *: : :: .: ..* :: : *:* * :::***:* .* ::.: : . : : *: :: : .:: ", "identical_positions": 97, "similar_positions": 257, "identity": "10.61%" }, { "cls_id": "homologset.agr.FB:FBgn0011016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43308-1", "uniprot_id": "SSRB_HUMAN", "id": "P43308-1", "name": "Translocon-associated protein subunit beta", "aln": "MRLLSFVVLALFAV-----TQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLN--VKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDG-PVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTP-KTKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPW5-1", "uniprot_id": "SSRB_MOUSE", "id": "Q9CPW5-1", "name": "Translocon-associated protein subunit beta", "aln": "MRLLAVVVLALLAV-----SQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLN--VKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDG-PVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTP-KPKKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F8A8-1", "uniprot_id": "F7F8A8_RAT", "id": "F7F8A8-1", "name": "Translocon-associated protein subunit beta", "aln": "MRSLVVVVLALLAV-----SQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSDLRHHFFFLNPWASASNVSHTVVLRPLKAGYFNFTSATITYLAQEDG-PVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTP-KPKKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUZ0-1", "uniprot_id": "Q9VUZ0_DROME", "id": "Q9VUZ0-1", "name": "Translocon-associated protein subunit beta", "aln": "MFKHLLTLFALCAVFSTCLSEDETRARLLVSKQILNKYLVEKSDLLVRYTIFNVGSGAATKVRLVDSGFHPEAFDVVGGQPT--AVVDRIAPQTNFTHVLVVRPKAFGYFNFTAAEVSYKAVEESETLQLAVSSEPGEGGIVNLNEYNKRFSSHFFDWVAFAVMTLPSLAIPLALWHQSKSKYERSGKNKKH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..::** ** :: * ****.**.:**:* ** ** ::*.*:****.** .*.* *..* ** *.:*.. : *. :*.:*.:*:** ******:* ::* * *:. .: :. :* **:***: .*:::***.**:**.**.******:.*** **:.** **: . * **:", "identical_positions": 85, "similar_positions": 58, "identity": "44.27%" }, { "cls_id": "homologset.agr.FB:FBgn0011020", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PYJ0-1", "uniprot_id": "E9PYJ0_MOUSE", "id": "E9PYJ0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEDLSQGKG--------------------------------SNHEKRKMESTAQITEEDSKLDEVVGLQKQICDLGTELTRQ----------------SSWWCVAHKDLQS----------QIDALIKENQEIRAELKT---LKKQDAEATKACIG----------------------------------SPTPARASNTL-----------------------------------------PVYVKIEGID---------------------------------------------------------------------------------SERTTSWDERD-----ELSGSPPNRSTMATG--------------------------------------------------------GTDSQ---------------------DEMLSFTSVDEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------VIHMSSKFLQR--SFGRMSPEPLSDSTFLDTESLADIWS-----------------SNPETSDGELLLHAQA----------------------------------------------------------------------------------SRVIPCFSPNALWVQNIPTKSRA---------PKEIQQTSDTTKTDETKEKRHPNGKVERMLSDGRTIITFPNGTRKEISADKKTTLIRFFNGDMKK--IKSDQKV--------------------------------IYYYADAQTMHTTYPDGVEVVQFPNKWTEKFYPDGSKETVFPDGTVKQLK----DGCEETVFPDGTFVTVKRNGDKTIMFSNGEKEIHTARFKRKEFPDGTTKTVYCNGCQETKYASGRVRVKDEKGTVILDWK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q046-1", "uniprot_id": "E9Q046_MOUSE", "id": "E9Q046-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHEPSLLQPESLLVTWRLNSQQRQAMLEDLSQGKG--------------------------------SNHKKRKMESTAQITEEDSKLDEVVGLQKQICDLGTELTRQ----------------SSWWCVAHKDLQS----------QIDALIKENQEIRAELKT---LKKQDAEATKACIG----------------------------------SPTSARASNTL-----------------------------------------PVYIKIEGID---------------------------------------------------------------------------------SERTTSWDERD-----ELSGSPPNRSTMATGGTDSQDERLSFTSVDEKPVYIKIEG---IDSERTTSWDERDELSGSPPNRSTMATGGTDSQ---------------------DERLSFTSVDEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------VIHMSSKFLQR--SFGRMSPEPLSDSTFLDTESLADIWS-----------------SNSETSDGELLLHAQA----------------------------------------------------------------------------------SRVIPCFSPNALWVQ------------------------------------------VERMLSDGRTIITFPNGTRKEISADKKTTLIRFFNGDMK---IKSDQKA--------------------------------IYYYADAQTMHTTYPDGVEVVQFPNKWTEKFYPDGSKETVFPDGTVKQLK----DGCEETVFPDGTFVTVKRNGDKTIMFSNGEKEIHTARFKRKEFPDGTTKTVYCNGCQETKYASGRVRVKDEKGTVILDWK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LM52-1", "uniprot_id": "A0ABK0LM52_RAT", "id": "A0ABK0LM52-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEDQSQGGGG-------------------------------PNNEKKKMEAKAQAPGEDSKTDEVVGLQKQISDLGTELTRQ----------------SSWWCVAHKDLQS----------QIDALIKENQEIRAELQT---LKKQDSEAPKAPTA----------------------------------SPSPPTATNTLVQQIFCITEIAAYEGCTLPCRHSLHWVPREGLTIINHTELTPVYIRIEGMD---------------------------------------------------------------------------------SEKTTSWDERDD----APSGSPQNGSTMATG--------------------------------------------------------GTDSL---------------------EERLSFTSLDEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------VIHMSSKFLQR--GFGRLSPEPLSDSTFLDTESPADIWS-----------------SNPDTSEGEILLQARA----------------------------------------------------------------------------------SRVLPCFPPNAVWLQNIPAKSRV---------PKEVQQTSDTTKEDETQEKRHSNGKVERLLSDGRTIITFPNGTRKEISADKKTTVIKFFNGDMKK--VKSDQRVHDQEYLGRKDFIWLTCPHHDIEGNHHHCRKLEIYYYADAQTTHTTYPDGVEVVQFPNKWTEKFYPDGSKETVFPDGTVKQLK----DGCEETVFPDGTFVTVKRNGDKTIMFSNGQKEIHTARFKRREFPDGTTKTVYCNGCQETKYASGRIRVKDETGTVILDWK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YUD2-1", "uniprot_id": "A0A8M6YUD2_DANRE", "id": "A0A8M6YUD2-1", "name": "", "aln": "-----------------------------------------------------MSAEIPRNRTSLESCLNPKTGCLESLQKLPMSPPYPTI-STSLSQEVLEEQQISEPDRTTSQTAQHDVKASR-------------------------RLPAENTGQKELLLQLQVQQLQRVLQEQNTLLSLISPGLILSP----------------------------------------AFLAPWQVQTPSSLSETDLLNSAGNSDAFKENLTKPTYFCELENESDALATENSSDVAPSAELRCLSPIKEESSDPTSEDCPLSPFGSRQGLLPNPEERPIRPGLRKEQTTFEEFVEEHLKTEQAVLQDNNQKQTRG------AEKRNFLRKGEGTSRLSNVKHFSKNTHRRRSVSPQMRSMKMLRPTDLHQKEMQQTSDLKESLNKTGAQQDNDLSSNKDGKDSAWTANITNNANSPKSKLNVGEMKSNGLAKGNKSCTNHQHNSVGFKKINDHIIKVHQK----------------------------------NNSPPTNHRWQNQSGKASKEVNLTNEVMESLSLSDSDHSSHSEDGPNSQSHKPFPHHVSRHT---------------------------------------------------------------------------------DHKDQSLDLSDG----DYASDAPSEIQFGEENRTSSPESLSSSSSSSDSELRSLEESNKTESRGADRTSAPQSLTKVFPQVWDTQEDTTHSV---------------------EQEKPYASIREEKEECNYNGEDGCKL---------------------------------------------------------------------------------------------------------------QKDLHEPQELRQQIWSLKQQLMNRESQWSQLHSVLQSRVETLVQENQHLQRRLTMGRRSSAPPSYSTYEKSREVTQMMPRVRSATPAFNKPSIHRTPQENANGGSIGTTGSS----------------------------------------------------------------------------------SRRNSVLSFDNLQNKDLITQGGKGSSFYHHPDHNDAQLTSQTRKDNVREETRYPDGRVERLFWSGSRVIIFRNGTKKEISLDKSVTVT-FFNGDVKR--TLADGTV--------------------------------IYYYCDAQTTHSTYPSGLEVVQFPNNQREKHHPDGTREISFPDGTVKILHS---DGQEESIFPDGTVVKISQHGEKVVEFTNGQREIHTTQYKRRIFPDGTIKTVYTNGRQETKFSSGRVRIKNNEGVIIMDKKST--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LZN8-1", "uniprot_id": "A0ABK0LZN8_RAT", "id": "A0ABK0LZN8-1", "name": "Centrosomal P4.1-associated protein", "aln": "MKMFLMPTSSELNTGQNFLTQWMTSPSRAGVILNREFPILDAD-EKQAATTVSASFPVKAAHFSSSFSISSEEDSFHEEQTLEAGRPYKPR-SEDPEAHPVSASVRREP-IASCQDAPGCQEGNRNAATPDLKSEFKEVANKNPLFKKLEQLKEIQQKKQEQLKRQQLEQLQRLMEEQEKLLTMVSGQHMFPG-SLLPDELSQKHRSPGDSASGERATLSPPS--YPNPTQDNSRASSLLPDEQSNFCRATQQDSVLTSKNAS-DLFHESQYHEAHVRRNDLKEESHNHPSGEGALPCWEKKMGKSQEGKDVNLQRS---RDSSGVVNIEERPIKAAIREKQQTFEDYLEEQIRLEERELRQKQLQEAEGPLLTKMKPKQPFLKRGEGLARFTNAKCKFQKGKESKLASTQSPSEQQSVPKVDRQHLQRKTALINRDLCADTTSVKKDSKARSKAGSASLRQKPKVTKTNRRDSLSPPGRKVQTGKKCDGQFRPQVKLERNVPTNNKENVPAYIKPWGAGCKVWNKTQGRDRLPLSTGPVGCVVSRSLVPETDRQTESSLDISLQKKLENWEREKEKENLELDEFLFLERAADEISFSSNSSFVLKILERDQQIYEGHRLSSTPVKAVQPQKAQQADPWGQSNHSEVPRPSVAHEDESEFEAMLLSRGS-GSP-GLRELSCKLSKKAFQNSTSENQGRWDAGDG-DVANSDSSSESEE-HDITIKPSTEAEDRVFSNREDSPQVCDAKGPSRDTGAQEDQWRDADLDLSDKECSSDESVTVESLSSQVLEPLRLPSSHDGSKVDFDDERSWADLEENPHEHGVVPREEAMSGTSQTHCHSTSEGCVLDKTIKRKIAPVKKGEDFSKSDRSVSPPPSDLMVKFFPSLKPKPKLDSHVENEPKLSLSQDQPP-------GDSVRSQVLREKVIELESEIEKFKAENTSLAKLRIERESALEKLRKEIADFEQQKARELARIEEYKKEETRKLQKERKVFEKYTAAARTFPDKKEREEIQALKQQIQELQEDLKRKETKWSSTHGRLRSQIEMLVKENTDLREEIKVMERFRLEAWKRAEAIENSPKACQYIMATKKDESMNSSIQFQKSHASLGVQGEKYKKKYLPAQDGVPHSSGNSSRRSKSVPPRDLGSLDKGQAALPREPLQPVNFPDLEYKNKEEKEEEIQGEINHPDGKVEKVYKNGCRVVLFPNGTRKEVSADGKSITVTFFNGDVKQ--VMPDERV--------------------------------VYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHFPDGRKEITFPDQTIKTLFA---DGQEESIFPDGTIVRVQRDGNKIIEFNNGQRELHTAQFKRREYPDGTVKTVYANGHQETKYTSGRVRVKDKDGNVLMDTEM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q569L8-1", "uniprot_id": "CPAP_MOUSE", "id": "Q569L8-1", "name": "Centrosomal P4.1-associated protein", "aln": "--MFLMPTSSELNSGQNFLTQWMTSPSRAGVILNRGFPILEAD-DKQAATNVSTSFPAKATHFSNSFSISSEEDSFHEEQKLEAGGPYKPW-SENPEAPPVFPSVRKEP-IASRQDAPGCQEDNNNDLTPHLESEFKEVANKNPLFKKLEQLKEIQQKKQEQLKRQQLEQLQRLMEEQEKLLTMVSAQHAFPG-TLLPDDQSQKHRSPGD------LTLPPHS--YSNPTQENSCASNVLPDEQSNFCRAT-QDSVLTSKNAS-DLFYESQYQEAHVKRNDLKEESPAHPSGEGALPRWEKKMGRSQEGKDVNLQKC---GDSSEVVNIDERPIKAAVREKQQTFEDYLEEQIQLEERELRQKQLQEAEGPLLAKTKPKQPFLKRGEGLARFTNAKSKFQKGKESKLASTQSPSEDQPGSKVDRQHLQRKTALINKDLCAETPTVKKDSKARPKAGFASLRQKPKVTKTNMRESLSPPGLKVQTGKKRDGQFRHQVKGERNAHASNKENVPACIKPWDAGCKMWSKTQGRERLPLSTGPVGCVVSRSPIRETDRETESSLDFSLQKKLEIWEREKEKENLELDEFLFLERAADEISFSSNSSFVLRILERDQQICDGHRLSSTPVKAVQQREAQQADPRGQSNCSEIPRYGVAHENESECEAMLLSWGS-GSPDGLRELSCKRSMKAFQTSTSEIQSQWDARDD-GVANSDSSTESEEQHDITIKPSTEVGDRVFSNREDSPQVCDAKGPIRDTGAQEDKWRDADLDLSDKECSSDESVIVESLNNKVLEPLRLPSSQAGSKIDFDDERSWTDLEENPYEHGVIHREEAIYGTPQTQCHSKSEGCVLDKTIKRKIAPVKKGEDFKCDRRISPPPPSDLMVKFFPSLKPKPKLDSHLENESKLNLSQDQPPEFMVCFIGDSVRSQVLREKVTELESEIEKFKAENTSLAKLRIERESALEKLRKEIADFEQQKARELARIEEYRKEETRKLQKERKVFEKYTAAARTFPDKKEREEIQALKQQIADLQEDLKRKETKWSSTQSRLRSQIEMLVKENTDLREEIKVMERFRLDAWKRAEAMENSPKACQYMMATKKDESMNSSFQFQKSHVSSGVQVEKYKKKYLPAQG-------NLSRRIKSAPPRDLGSSDKGQAALPREPLQQVNFPDLEYKNKEEKEEEIQGEISHPDGKVEKIYKNGRRVVLFPNGTRKEVSADGKSVTVTFFNGDVKQ--VMPDERV--------------------------------VYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHFPDGRKEITFPDQTIKTLFA---DGQEESIFPDGTIVRVQRDGNKIIEFNNGQRELHTAQFKRREYPDGTVKTVYANGHQETKYTSGRVRVKDKDGNVLMDTEM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC77-1", "uniprot_id": "CPAP_HUMAN", "id": "Q9HC77-1", "name": "Centrosomal P4.1-associated protein", "aln": "--MFLMPTSSELNSGQNFLTQWMTNPSRAGVILNRGFPILEADKEKRAAVDISTSFPIKGTHFSDSFSFINEEDSLLEEQKLESNNPYKPQ-SDKSETHTAFPCIKKGPQVAACHSAPGHQEENKNDFIPDLASEFKEGAYKDPLFKKLEQLKEVQQKKQEQLKRQQLEQLQRLMEEQEKLLTMVSGQCTLPGLSLLPDDQSQKHRSPGNTTTGERATCCFPSYVYPDPTQEETYPSNILSHEQSNFCRTAHGDFVLTSKRASPNLFSEAQYQEAPVEKNNLKEENRNHPTGESIL-CWEKVTEQIQEANDKNLQKH---DDSSEVANIEERPIKAAIGERKQTFEDYLEEQIQLEEQELKQKQLKEAEGPLPIKAKPKQPFLKRGEGLARFTNAKSKFQKGKESKLVTNQSTSEDQPLFKMDRQQLQRKTALKNKELCADNPILKKDSKARTKSGSVTLSQKPKMLKCSNRKSLSPSGLKIQTGKKCDGQFRDQIKFENKVTSNNKENVTECPKPCDTGCTGWNKTQGKDRLPLSTGPASRLAAKSPIRETMKESESSLDVSLQKKLETWEREKEKENLELDEFLFLEQAADEISFSSNSSFVLKILERDQQICKGHRMSSTPVKAVP-QKTNPADPISHCNRSED-LDHTAREKESECEVAPKQLHSLSSADELREQPCKIR-KAVQKSTSENQTEWNARDDEGVPNSDSSTDSEEQLDVTIKPSTEDRERGISSREDSPQVCDDKGPFKDTRTQEDKRRDVDLDLSDKDYSSDES-IMESIKHKVSEPSRS-SSLSLSKMDFDDERTWTDLEENLCNHDVVLGNESTYGTPQT-CYPNNEIGILDKTIKRKIAPVKRGEDLSKSRRSRSPPTSELMMKFFPSLKPKPKSDSHLGNELKLNISQDQPP-------GDNARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKYTTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESS------LEVEKKDKLANTSVRFQNSQISSGTQVEKYKKNYLPMQG-------NPPRRSKSAPPRDLGNLDKGQAASPREPLEPLNFPDPEYK-EEEEDQDIQGEISHPDGKVEKVYKNGCRVILFPNGTRKEVSADGKTITVTFFNGDVKQ--VMPDQRV--------------------------------IYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHYPDGRKEITFPDQTVKNLFP---DGQEESIFPDGTIVRVQRDGNKLIEFNNGQRELHTAQFKRREYPDGTVKTVYANGHQETKYRSGRIRVKDKEGNVLMDTEL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI72-1", "uniprot_id": "Q9VI72_DROME", "id": "Q9VI72-1", "name": "", "aln": "---------------------------------MQEAGESPVGMPLSQEAIAQRLAALSRWQDEQKRLLQERQSNHRVLLGLEQRNMYKMLGLLHQETESHENSVLEEWDEEHSIQMPRLAADPDEHEPEISMADPQPAKPKRPFLRRGEGLKQRFKINPDQLRLENLPRYKFANAHPQFRTPQMKKG-----------------------------------------ILKKQVKSPPNPAPPPAPKPSAQLDDLNEQRFQQMLIGKNACSSTPDLKSSYASSTTASSTSPRVRFVEQKSRAGQTTHADDEASSEASPMTGVCWAKVLDTQSIKPAQIQRRSAQIRVEDDSNVSIFELLEQKATEGNIDMN--------------------SSCIRTFMARKDQRRRVADDSDHIVVTQQVRQMRLQPQVDQMLVQELQEGDEEDTEPSSDQTLTMTPIQVGNTKVRVRFSDSNDTHEYSDATSLNDGSNIQLFEQFKSALFQALEQKKKSSPS----------------------------------KESDEPITKDLQEKANLVRTRLEELETEIATFKEQNAQLLRLRQQHELEKAKCTQDHMEAMER-----------------------------------------------------------------------------VHDEKIQAEIYLHDERMKIEEERRKFEQQMRLQKSNANSKEKKEIAALKQEVEGLQLQLKQKEQAHVSAQARLRAQLRASEKEQRNYRDEIELLRK--------------------ENKRLEQELVKIG--------------------------------------------------------------------------------------------------------------------------------------------------------------------RENNSKMLQEINRNIARLAPKVLPSATMSDILDENGRRTQSLDGTAG-KPAKQREAQNRRQSSGSAQVRSRSR---------------------------------------------------------------------------------SLSRNKKTPYALDESYASSSSVESE-------EVQPPVTAPKAATPPPAANSSSDFKREITNADGSKDIWYPNGNLKKISADGMNLRMLYFNKDIKETNIREGT---------------------------------VKYYYAETNTWHTSYLDGLEILEFPNGQTEHRRKDGTVEIHFPNNSIKIVDPSDTEKLEEWRYADGTHLVQLRNGDKILNLPNGQKEIHTKLNKRREYPDGTVKLVYPDGSQETRYSNGRVRLKDKDGKLIMDTDYAKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: : : : . . . : . . : . : :: .. * . :: .: : : : : :. . . . . .. . . : * .* : : **. *::* * :** *:* . ***. ::* *::* .*:*::.*.. *: ** * **: ::* : : ** :.*** : :.*:* : : **::*:** **: :**** * ** :* ***:: .**:*:*:: * :::* . ", "identical_positions": 60, "similar_positions": 90, "identity": "4.25%" }, { "cls_id": "homologset.agr.FB:FBgn0011202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z207-1", "uniprot_id": "DIAP3_MOUSE", "id": "Q9Z207-1", "name": "Protein diaphanous homolog 3", "aln": "-----------------------------MERHRARALG--------------------RDSKSSRRKGLQSAPP-AGPYEPGEKRPKLHLNIRTLTDDMLDKFA-------------SIRIP-GSKKERPPLPHLKTVSGISDSSSLSSETMENNPKA-----------------LPESEVLKLFEKMMED----MNLNEDKKAPLREKDFGIKKEMVMQYINTASKT-------GSLRSSR----------------------------QISPQEFLHELKMG------------------------------------------------------------YTDERLFTYLESLRVSLTSHPVSWVQSFGHEG-----LGLLLDILEKLINGQIQEK--VVKKTQHKVIQCLRALMNT---QYGLERIMSDKRS--------------LSLLAKAMDPRQPAMMADVVKLLSAVCIVGE-ESILE------------------EVLEALTSAGEE--RKIDRFFSIVEG---LRHN-----SVNLQVACMQLINALVTSPDDLDFRLHLRNEFMRCGLKEILPNL----KGIKNDGLDIQLKVFDEHKEEDL-SEFFHRLEDIRAELDEASDVYSMLWDTVKETRAEGHFLSILQHLLLIRNDRFIREQYFKLIDECVSQIVLHRD--GTDPDFTYRKRLDLDLSQFVDVCIDQAKLDEWEEKASEHCKKFEKECTDHQETQAQLQKRE----------------------AKINELQAELQAFKSQFG------------------------------------------------------------------------------------------------------------ALPPGTKIPLQPSVEGEAGPSALPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APPALSGGVPPPPPPP------------------------------PPPPPPLPGMPMPFGGP--------VPPPPP--------LGFLGGQSSIPLN-----------LPFGLKPKKEFKPEI-SMRRLNWLKIGPNEMSENCFWIKVNENKYEN----RDLLCKLENTFCCQEKE---KRNTNDFDEKKV------IKKRMKELKFLDPKIAQNLSIFLS-SFR-VPYEKIRTMILEVDETQLSESMIQNLIKHLPDEEQLKSLSQFRSDYNSLCEPE-----QFAVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKGFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKSADQKTTLLHFLVDVCEEKHADILHFVDDLAHLDKASRVSVEMLEKNVKQMGRQLQQLEKNLETFPPPEDL----HDKFVIKMSSFVISANEQYEKLSTLLGSMTQLYQSIMGYYAVDM-KKVSVEEFFNDLNNFRTSFMLALKENIKKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDETG-------VMDSLLEALQSG----AAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLTEGSRPHHSINCNSTRTPVAKELNYNLDTHASTGRIKAVEK-EACNAESNKKKEMELLGSVAKSESVPEVEALLARLRAL-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LVW7-1", "uniprot_id": "DIAP3_RAT", "id": "F1LVW7-1", "name": "Protein diaphanous homolog 3", "aln": "-----------------------------MEKHRARALG--------------------RDSKASRRKGLPSAPP-AGPYELGEKRPKLHLNIRTLTDDMLDKFA-------------SIRIPKGSKKERPPLPQLKTVSGSSDYSSVSSETMENNPKS-----------------LSENEVLKLFEKMMED----MNLNEDKKAPLREKDFSIKKEMVMQYINTASKT-------GSLRSSR----------------------------QISPQEFIHELKMG------------------------------------------------------------YTGERLFTYLESLRVSLTSNPVSWVQNFGHEG-----LGLLLDILEKLINGQIQEK--VVKKTQHKVIQCLRALMNT---QYGLERIMSDERS--------------LSLLAKAMDPKQPSMMADVVKLLSAVCIVGE-ESILE------------------EVLEALTSAGEE--RKIDRFFSIVEG---LRHN-----SVQLQVACMQLINALVTSPDDLDFRLHLRNEFMRCGLKEILPNL----KGIKNDGLDIQLKVFDEHKEEDL-SEFSHRFEDIRAEFDEASDVYSVVWDTVKETRAEGHFVSILQHLLLIRNDRFIRQQYFKLIDECVSQIVLHRD--GIDPDFTYRKRLDLDLSQFVDVCIDQAKLEEWEEKASEHCKKFEKECTDHQETQAQLQKKE----------------------AKINELQAELQAFKSQFG------------------------------------------------------------------------------------------------------------ALPPGTKIPLQTSAKGEPGPSAFPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APPALGAGVPPPPPPP------------------------------PPPPPPLPGMAMPFGGP--------VPPPPP--------LGFLGGQNFIPLN-----------LPFGLKPKKEFKPEI-SMRRLNWLKIGPNEMSENCFWIKVNENKYEN----KDLLCKLENTFCCLEKE---KRDTNDFDEKKV------IKKRMKELKFLDPKIAQNLSIFLS-SFR-VPYEKIRTMILEVDEAQLSESMIQNLMKHLPDEEQLKSLSQFRSDYNSLCEPE-----QFAVVMSNVKRLRPRLTAILFKLQFEEQVNNINPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKSADQKTTLLHFLVDVCEEKHPDILPFVDDLAHLDKASRVSVEMLEKSLKQMGRQLLQLEKNLETFPPPEDL----HDKFVIKMSSFIITAKEHYGKLSTLLDNMTQLYQSVMSYYAVDT-KKVSVEEFFNDLNNFRTSFMQALKENIRKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDETG-------VMDSLLEALQSG----AAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLSEGSRPHHSINCTSTRTPVAKELNCNLDTHTSTGRIKAVEK-EACNAESNRKKEMELLGSVSKSESVPEVEALLARLRAL-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NSV4-3", "uniprot_id": "DIAP3_HUMAN", "id": "Q9NSV4-3", "name": "Protein diaphanous homolog 3", "aln": "-----------------------------MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFA-------------SIRIP-GSKKERPPLPNLKTAFASSDCSAAPLEMMENFPKP-----------------LSENELLELFEKMMED----MNLNEDKKAPLREKDFSIKKEMVMQYINTASKT-------GSLKRSR----------------------------QISPQEFIHELKMG------------------------------------------------------------SADERLVTCLESLRVSLTSNPVSWVESFGHEG-----LGLLLDILEKLISGKIQEK--VVKKNQHKVIQCLKALMNT---QYGLERIMSEERS--------------LSLLAKAVDPRHPNMMTDVVKLLSAVCIVGE-ESILE------------------EVLEALTSAGEE--KKIDRFFCIVEG---LRHN-----SVQLQVACMQLINALVTSPDDLDFRLHIRNEFMRCGLKEILPNL----KCIKNDGLDIQLKVFDEHKEEDL-FELSHRLEDIRAELDEAYDVYNMVWSTVKETRAEGYFISILQHLLLIRNDYFIRQQYFKLIDECVSQIVLHRD--GMDPDFTYRKRLDLDLTQFVDICIDQAKLEEFEEKASELYKKFEKEFTDHQETQAELQKKE----------------------AKINELQAELQAFKSQFG------------------------------------------------------------------------------------------------------------ALPADCNIPLPPSKEGGTGHSALPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPLPSGGG-VPPPPP------------------------------PPPPPPLPGMRMPFSGP--------VPPPPP--------LGFLGGQNSPPLPI----------LPFGLKPKKEFKPEI-SMRRLNWLKIRPHEMTENCFWIKVNENKYEN----VDLLCKLENTFCCQQKE---RREEEDIEEKKS------IKKKIKELKFLDSKIAQNLSIFLS-SFR-VPYEEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSLSQFKSEYSNLCEPE-----QFVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPEDL----HDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYYAIDV-KKVSVEDFLTDLNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQKKKRLLEMKTEGDETG-------VMDNLLEALQSG----AAFRDRRKRTPMPKDVRQSLSPMSQRPVLKVCNHENQKVQLTEGSRSHYNINCNSTRTPVAKELNYNLDTHTSTGRIKAAEKKEACNVESNRKKETELLGSFSKNESVPEVEALLARLRAL-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70566-1", "uniprot_id": "DIAP2_MOUSE", "id": "O70566-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MEELGAAASGAGGGG-------------GGGEEHGGGRSNKRGAGNRAANEEETRNKPKL-----------RDRIT-------------SFRKS-ATKREKPVIQHSIDYQTAVVEIPPALIVHDDRSLI-----------------LSEKEVLDLFEKMMED----MNLNEEKKAPLRKKDFSIKREMVVQYISATSKSIVGSKVLGGLKNSKHEF-------------------------TLSSQEYVHELRSG------------------------------------------------------------ISDEKLLNCLESLRVSLTSHPVSWVNNFGYEG-----LGVLLDVLEKLLDKKQQEN--IDKKNQYKVIQCLKAFMNN---KFGLQRILGDERS--------------LLLLARAIDPKQQNMMTEIVKILSAICIVGE-ENILD------------------KLLGGITAAAEL--NNRERFSPIVEG---LENNE----ALHLQVACMQFINALVTSPYDLDFRIHLRNEFLRCGLKAMLPTL----KEIENEGLDIQLRVFEENKEDDL-SELSHRLNDIRAEMDDINEVYHLLYNMLKDTAAEPYLLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCS--GMDPDFKYRQRIDFDFTHLLDACVNKAKVEENEQKAMEFSKKFDEEFTARQEAQAELQKRD----------------------EKIKELETEIQQLRGQG-------------------------------------------------------------------------------------------------------------VPSAIPGPPPPPPLPG-AGPCPPPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPPPPPPLPGVVPPP------------------------------PPPLPGMPGIPPPPPPP-------LSGVPPP--------PPPPGGVFPLLSGP--------IELPYGMKQKKLYKPDI-PMKRINWSKIEPKELSENCVWLKLKEEKYEN----ADLFAKLALTFPSQMKG---QRNTEAAEENRSG----PPKKKVKELRILDTKTAQNLSIFLG-SYR-MPYEEIKNIILEVNEEMLSEALIQNLVKYLPDQNALRELAQLKSEYDDLCEPE-----QFGVVMSTVKMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLACEELKKSESFKRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKSADQKSTLLHFLAEICDEKYRDILKFPDELEHVESAGKVSAQILKSNLVAMEQSILHLEKNIKNFPPAESH----HDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDP-NTVNMEEFFGDLNTFRTLFLEALKENHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETG-------VMDNLLEALQSG----AAFRDRRKRIPRNPD-----------------NRRPPLERSR--SRHNGAMSSK------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZUN2-1", "uniprot_id": "A0A8I5ZUN2_RAT", "id": "A0A8I5ZUN2-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MEQPGAAASGAGGGG-------------GG-EEPGVGRSNKRGTGNRAANEEETKNKPKLNIQIKTLADDVRDRIT-------------SFRKS-AIKKEKPLIQHPTDSQAAMGEVPSAQILHDERSLI-----------------LSEKEVLDLFEKMMED----MNLNEEKKAPLRDKDFTTKREMVVQYISATAKSIVGSKVMGGLKNNKHEF-------------------------TLSSQEYVHELRSG------------------------------------------------------------ISDEKLLNCLESLRVSLTSNPVSWVNNFGYEG-----LGVLLDVLEKLLDKKQQEN--IDKKNQYKIIQCLKAFMNN---KFGLQRILGDERS--------------LLLLARAIDPKQQNMMTEIVKILSAICIVGE-ENILD------------------KLLGGITAAAER--NNRERFSPIVEG---LENNE----ALHLQVACMQFINALVTSPYDLDFRIHLRNEFLRCGLKAMLPSL----KEKENDELDIQLRVFEENKEDDL-TELSHRLNDIRAEMDDMNEVFHLLYNMLKDTAAEGYLLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCS--GMDPDFKYRQRIDFDFTHLIDACVNKAKVEESEQKAMEFSKKFDEEFTARQEAQAEIQKRD----------------------EKIKELESEIQQLQAQG-------------------------------------------------------------------------------------------------------------PGSAFPGPPPPPPLPG-AGPCPPPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPPP---LPGVGPPP------------------------------PPPLPGT----APPPPP-------LFGAPLL--------PPPPGGITPSLPGP--------VELPYGMKQKKLYNPEV-SMKRINWSKIEPRDLSENCVWLKLKEEKYEN----PDLFAKLALTFPSQMKG---QRHGETSEENRIG----PQKKKMKELRILDTKTAQNLSIFLG-SYR-MPYEEIKNIILEVNEELLSEALIQNLVKYLPEQNVLRELAQLKNEYDDLCEPE-----QFGVVMSTVNMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLACEELKKSESFNRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKSADQKTTLLHFLAEICDEQHRDILKFPEELEHVESASKVSAQILKSNLVAMEQSILHLESNIKNFPKAESL----HDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDP-NIVTIEEFFGDLNTFRTLFLEALKENHKRKEMEEKSRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETG-------VMDNLLEALQSG----AAFRDRRKRIPRNPD-----------------NRRPTLERSR--SRHNGAMPSK------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60879-1", "uniprot_id": "DIAP2_HUMAN", "id": "O60879-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MEQPGAAASGAGG----------------GSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRIT-------------SFRKS-TVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLN-----------------LSEKEVLDLFEKMMED----MNLNEEKKAPLRNKDFTTKREMVVQYISATAKS-------GGLKNSKHEC-------------------------TLSSQEYVHELRSG------------------------------------------------------------ISDEKLLNCLESLRVSLTSNPVSWVNNFGHEG-----LGLLLDELEKLLDKKQQEN--IDKKNQYKLIQCLKAFMNN---KFGLQRILGDERS--------------LLLLARAIDPKQPNMMTEIVKILSAICIVGE-ENILD------------------KLLGAITTAAER--NNRERFSPIVEG---LENQE----ALQLQVACMQFINALVTSPYELDFRIHLRNEFLRSGLKTMLPDL----KEKENDELDIQLKVFDENKEDDL-TELSHRLNDIRAEMDDMNEVYHLLYNMLKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCS--GMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRD----------------------EKIKELEAEIQQLRTQAQ---------------------------------------------------------------------------------------------------------VLSSSSGIPGPPAAPPLPG-VGPPPPPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APPLPG---GAPLPPP------------------------------PPPLPGMMGIPPPPPPPL------LFGGPPP--------PPPLGGVPPPPGIS--------LNLPYGMKQKKMYKPEV-SMKRINWSKIEPTELSENCFWLRVKEDKFEN----PDLFAKLALNFATQIKV---QKNAEALEEKKTG----PTKKKVKELRILDPKTAQNLSIFLG-SYR-MPYEDIRNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPE-----QFGVVMSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQ----HDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFDS-KTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETG-------VMDNLLEALQSG----AAFRDRRKRIPRNPD-----------------NRRVPLERSR--SRHNGAISSK------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZW8-1", "uniprot_id": "A0A8M9PZW8_DANRE", "id": "A0A8M9PZW8-1", "name": "Protein diaphanous homolog 2", "aln": "-----------------------------MDQQAAGGE----------------------------DPNK--PSKKKSSEDESKN-KKLNIHIKTLADDMRDRIT-------------SFRKQ-GMKKEKPLIQHPTDPISTQTELPVPQPFFDERSMN-----------------LSEKEIVDLFEKMMED----MNLNEERKAPLRGKDLSTKREMVVQYISATAKSITGSKVAGGLRNSKHEC-------------------------TLSSQEYVHELRSG------------------------------------------------------------ISEDKLLNCLESLRVSLTSNPVSWVNNFGHEG-----LGLLLDALERLLDKKQQEN--IDKKNQHKLIQCLKAFMNN---KYGLQRILGDERS--------------LLLLARAIDPKQTNMMTEIVKILSAVCIIGE-ENILD------------------KILAAMTIAAER--NNKERFAPIVEG---LENHE----AQQLQVACMQLINALVTSPDDLDFRIHLRNEFLRCGLKKILPEL----KET--EELDIQLKVFNENKEEDS-IELSHRLDDIRAEMDDMGEVYHLLSNMVKDTGSEPYFLSILQHLLLIRNDYYIRPQYYKVIEECVSQIVLHRS--GMDPDFAYRERLDVDFSHLIDQCVDKAKVDESEQRAAEFSKKFDEEFSARQEAQAELQKQE----------------------EKIKAFESQINTLQAQLTSERDKLKEAEKSISERN-------------------------------------------------------------------------------------SKIAAGPKAAGAGPPPPPPPPGGIAPPPPPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPPPIG--GAPPPPP------------------------------PPPFPASLGPPPPPPPP-------GCGPPPP--------PPPPGGGPPPPPGMPSAPPPLVVQLPYGLAPKKTYKPDS-IMKRVNWSKIVPQEMAENCFWLKVKEERFEN----TDMFSELSLSFSSKSRV---KKDVEETDD-RMT----QFKKKAKELRILDAKTAQNLSIFLG-SFR-LPYEEIRDIVLQVDEERLSEALIQNLIKNLPEQKELSNLAELKNEYEELCESE-----QFGIVMSSVKMLRPRLNGILFKLTFEEQVNNIRPDIMNVTFACEEVKKSEGFHMLLEMVLLVGNYMNSGSRNAQTFGFNISFLCKLRDTKSTDQNTTLLHFLAEKCEEKYPEMLKFPDELEHVESASKVAAQTLKASLDIMERHIQRLENDIQNFPKTDDK----QDKFVEKMSGFSKHSREQYEKLSTMHKNMQKLYENLGSYFAFDP-HTVSIEDFFGDLANFRNLFMDAVRENHKKREMEEKIKRAKIAKEKAEREKIERQQKKKQLIDMNKEGDETG-------VMDSLMEALQSG----AAFRDRRKRTPRNGDQ----SPSCSAPRWPGANHDAASGKSRQPSHWFGKIPFAPQCKPYGPMIACRLRTFAKCQRPKSGDNTEEG----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O08808-1", "uniprot_id": "DIAP1_MOUSE", "id": "O08808-1", "name": "Protein diaphanous homolog 1", "aln": "-----------------------------MEPSGGGLGP-----------------------GRGTRDKKKGRSPDELPATGGDGGKHKKF---------LERFT-------------SMRIK--KEKEKPNSAHRNSS-ASYGDDPTAQSLQD----------------------ISDEQVLVLFEQMLVD----MNLNEEKQQPLREKDIVIKREMVSQYLHTSKAG------MNQKESSR------------------------------SAMMYIQELRSG------------------------------------------------------------LRDMHLLSCLESLRVSLNNNPVSWVQTFGAEG-----LASLLDILKRLHDEKEETSGNYDSRNQHEIIRCLKAFMNN---KFGIKTMLETEEG--------------ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNE------------------RVLEAMTERAEM--DEVERFQPLLDG---LKSGT----SIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQEL----REIENEDMKVQLCVFDEQGDEDF-FDLKGRLDDIRMEMDDFGEVFQIILNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECVSQIVLHKN--GTDPDFKCRH-LQIDIERLVDQMIDKTKVEKSEAKATELEKKLDSELTARHELQVEMKKMENDFE------------------QKLQDLQGEKDALDSEKQQITAQKQDLEAEVSKLTGEVAKLSKELEDAKNEMASLS----------------------------------------------------------------AVVVAPSVSSSAAVPPAPPLPGDSGTVIPPPPPPPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPGGVVPPSPP--LPPGTCIPPPPPLPGGACIPPPPQLPGSAAIPPPPPLPGVASIPPPPPLPGATAIPPPPPLPGATAIPPPPP-----------------------LPGGTGIPPPPPPLPGSVGVPPPPP-LPGGPGLPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGVPAAPVLPFGLTPKKVYKPEV-QLRRPNWSKFVAEDLSQDCFWTKVKEDRFEN----NELFAKLTLAFSAQTKTSKAKKDQEGGEEKKS-----VQKKKVKELKVLDSKTAQNLSIFLG-SFR-MPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKEEYDDLAESE-----QFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSADQKMTLLHFLAELCENDHPEVLKFPDELAHVEKASRVSAENLQKSLDQMKKQIADVERDVQNFPAATDE----KDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDP-KKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETG-------VMDSLLEALQSG----AAFR--RKRGPRQVN-----------------RKAGCAVTSLLASELTKDDAMAPGPVKVPKKSEGVPTILEEAKELVGRAS--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M775-1", "uniprot_id": "DIAP1_RAT", "id": "F1M775-1", "name": "Protein diaphanous homolog 1", "aln": "-----------------------------MEPSGGGLGP-----------------------GRGTRDKKKGRSPDELPATGGDGGKHKKFTLKRLMADELERFT-------------SMRIK--KEKEKPNSAHRNSS-ASYGDDPTAQSLQD----------------------ISDDQVLVLFEQMLVD----MNLNEEKQQPLREKDIVIKREMVSQYLHTSKAG------MNQKESSR------------------------------SAMMYIQELRSG------------------------------------------------------------LRDMHLLSCLESLRVSLNNNPVSWVQTFGAEG-----LASLLDILKRLHDEKEETSGNYDSRNQHEIIRCLKAFMNN---KFGIKTMLETEEG--------------ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNE------------------RVLEAMTERAEM--EEVERFQPLLDG---LKSGT----SIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQEL----REIDNDDMRVQLNVFDEQGDEDF-FDLKGRLDDIRMEMDDFGEVFQIILNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECVSQIVLHKN--GTDPDFKCRH-LQIDIEGLVDQMIDKTKVEKSEAKATELEKKLDSELTARHELQVEMKKMENDFE------------------QKLQDLQGEKDALDSEKQQITTQKQDLEAEVSKLTGEVAKLSKELEDAKKEMASLS----------------------------------------------------------------AVAVAPSVSSSAAVPQAPPLPGTSGTVIPPPPPPP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPGGAVPPPPPPPLPAGTGIPPPPPLPGGACISSSPQLFGSTAIPPPPPLPGATAIPPPPPLPGDTAIPPPPPLPGXTAIPPPPP-----------------------LPGATGVPPPPPPLPGSVGVPPPPP-LPGGPGLPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGIPAAPVLPFGLTPKKVYKPEV-QLRRPNWSKFVAEDLSQDCFWTKVKEDRFEN----NELFAKLTLAFSAQTKTSLAKKDQEGGEEKKS-----VQKKKVKELKVLDSKTAQNLSIFLG-SFR-MPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKEEYDDLAESE-----QFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSADQKMTLLHFLAELCETDHPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQIADVERDVQNFPAATDE----KDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDP-KKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETG-------VMDSLLEALQSG----AAFR--RKRGPRQVN-----------------RKAGCAVTSLLASELTKDDAVAASSAKVPKKSEGVTTILEEAKELVGRAS--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60610-1", "uniprot_id": "DIAP1_HUMAN", "id": "O60610-1", "name": "Protein diaphanous homolog 1", "aln": "-----------------------------MEPPGGSLGP-----------------------GRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFT-------------SMRIK--KEKEKPNSAHRNSS-ASYGDDPTAQSLQD----------------------VSDEQVLVLFEQMLLD----MNLNEEKQQPLREKDIIIKREMVSQYLYTSKAG------MSQKESSK------------------------------SAMMYIQELRSG------------------------------------------------------------LRDMPLLSCLESLRVSLNNNPVSWVQTFGAEG-----LASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNN---KFGIKTMLETEEG--------------ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNE------------------RVLEAMTERAEM--DEVERFQPLLDG---LKSGT----TIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDL----REIENEDMRVQLNVFDEQGEEDS-YDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKN--GADPDFKCRH-LQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFE------------------QKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAA--------------------------------------------------------------AITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPP----------------------LPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP-FPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEV-QLRRPNWSKLVAEDLSQDCFWTKVKEDRFEN----NELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS-----VQKKKVKELKVLDSKTAQNLSIFLG-SFR-MPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESE-----QFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDE----KDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP-KKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETG-------VMDSLLEALQSG----AAFR--RKRGPRQAN-----------------RKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTILEEAKELVGRAS--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48608-1", "uniprot_id": "DIA_DROME", "id": "P48608-1", "name": "Protein diaphanous", "aln": "------------------------------------------------------------------------MSRHEKTKSTGGG----------LLDSLFGRPS-------------KSKGG---TISSGTLAHGGRPVSADNYVVPGVEDFEQYIQQ-----------------LSVAELDAKFLEIIED----MNIPKDKREPLLAKSKEERQKMIMWHLKGKNSL-------ERSANSR----------------------------FEKPIDYVEYLQNGE-----------------------------------------------------------HSTHKVYQCVESLRVALTSNPISWIKEFGVAG-----IGTIEKLLARSKNNASYEK------IEFEAIRCLKAIMNN---TWGLNVVLNPDQHS------------VVLLLAQSLDPRKPQTMCEALKLLASFCIVYE-RNGYE------------------KVLRAITTIAATSFKASERFRPIVDA---LFASDQQDPKRDLACHSLIFINTLTNTPTDLNFRLHLRCEIMRMGLYDRLDEFTKIVEASNNENLQQHFKIFNEIREDDF-EEFVQRFDNVTFNMDDATDCFDVLKNLVTDTTSEPYFLSILQHLLYIRDDFYFRPAYYQLIEECISQIVFHKG--YCDPNFENRN-FNIDTSLLLDDIVEKAKAKESK-RSEEYEKKIEQLESAKQEAEAKAAHLE----------------------EKVKLMEANGVAAPSPNK--------------------------------------------------------------------------------------------------------------LPKVNIPMPPPPPGGGGAPPPPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPMPGRAGGGPPPPP------------------------------PPPMPGRAGGPPPPPPPP----GMGGPPPPP-----MPGMMRPGGGPPPPPMMMG---PMVPVLPHGLKPKKKWDVKN-PMKRANWKAIVPAKMSDKAFWVKCQEDKLAQ----DDFLAELAVKFSSKPVK---KEQKDAVDKPTT------LTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIE-----QFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCD----DDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDP-SKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRLQEAREQSAREQQERQQRKKAVVDMDAPQTQEG-------VMDSLLEALQTG----SAFGQRNRQARRQRP----------------AGAERRAQLSRSRSRTRVTNGQLMTREMILNEVLGSA----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41832-1", "uniprot_id": "BNI1_YEAST", "id": "P41832-1", "name": "Protein BNI1", "aln": "MLKNSGSKHSNSKESHSNSSSGIFQNLKRLANSNATNSNTGSPTYASQQQHSPVGNEVSTSPASSSSFRKLNAPSRSTSTEARPLNKKSTLNTQNLSQYMNGKLSGDVPVSSQHARSHSMQSKYSYSKRNSSQASNKLTRQHTGQSHSASSLLSQGSLTNLSKFTTPDGKIYLEMPSDPYEVEVLFEDIMYKRNIFQSLSEDKQEALMGYSIEKKWLIVKQDLQNELKKMRANTTSSSTASRTSMASDHHPILTANSSLSSPKSVLMTSASSPTSTVYSNSLNHSTTLSSVGTSTSKGKKLVSGSLKKQPSLNNIYRGGAENNTSASTLPGDRTNRPPIHYVQRILADKLTSDEMKDLWVTLRTEQLDWVDAFIDHQGHIAMANVLMNSIYKTAPRENLTKELLEKENSFFKCFRVLSMLSQGLYEFSTHRLMTDTVAEGLFSTKLATRKMATEIFVCMLEKKNKSRFEAVLTSLDKKFRIGQNLHMIQNFKKMPQYFSHLTLESHLKIIQAWLFAVEQTLDGRGKMGSLVGASDEFKNGGGENAILEYCQWTMVFINHLCSCSDNINQRMLLRTKLENCGILRIMNKI----KLLDYDKVIDQIELYDNNKLDDFNVKLEANNKAFNVDLHDPLSLLKNLWDICKGTENEKLLVSLVQHLFLSSSKLIEENQNSSKLTKQLKLMDSLVTNVSVASTSDEETNMNMAIQRLYDAMQTDEVARRAILESRALTKKLEEIQAERDSLSEKLSKAEHGLVGQLEDELHERDRILAKNQRVMQQLEAELEELKKKHLLEKHQQEVELRKMLTILNSRPEESFNKNEGTRGMNSSLNSSEKANIQKVLQDGLSRAKKDYKDDSKKFGMTLQPNKRLKMLRMQMENIENEARQLEMTNFAEFEKDRLEPPIHIKKPKVKKMKNKDRKPLVKPQEADVNKLNDLRRALAEIQMESNDISKFNVEERVNELFNEKKSLALKRLKELETKYKGFGIDFNVDEIMDSPKKNTGDVETEEDANYASLDPKTYQKKLDEINRITDQLLDIQTQTEHEIQVEEDGESDLSSSSSDDESEEIYQDASPTQELRSEHSELSSGSGPGSFLDALSQKYGTGQNVTASAAFGENNNGSGIGPLHSKVEKTFMNRLRKSTVSSAPYLEELTQKVNKVEPYEQNEDEGLDKKSLPENSTASAASAFDKAEKDMRQHVENGKQGRVVNHEEDKTADFSAVSKLNNTDGAEDLSTQSSVLSSQPPPPPPPPPPVPAKLFGESLEKEKKSEDDTVKQETTGDSPAPPPPPPPPPPPPMALFGKPKGETPPPPP--LPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSLFEKYPRPHKKLKQLHWEKLDCTDNSIWGTGKAEKFADDLYEKGVLADLEKAFAAREIKSLASKRKEDLQKITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTPSVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLMVNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNFMN--DTSKQAQGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLYIKHKKIVEEQQKRAQEKEKQKENSNSPSSEGNEEDEAEDRRAVMDKLLEQLKNAGPAKSDPSSARKRALVRKKYLSEKDNAPQLLNDLDTEEGSILYSPEAMDPTADTVIHAESPTPLATRGVMNTSEDLPSPSKTSALEDQEEISDRARMLLKELRGSDTPVKQNSILDEHLEKLRARKERSIGEASTGNRLSFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : . :: * .:: . .: :::: .* . : :: : .. : . *. . ::.* *:* .. :.*:. * : . : : .. : :::. :. . :: ::. :: : . * : : : .:: . :: :: . : : :** * . . ::: *: :* :: . *: : : . : : :: :::: :* .: . . . ::.: . : . . : * ::*::**:: .. . . : : :. : . . ::. : * . . .: **::. : :.. . : : : :: :: : * . * .. *** .*. * . * * . :. :: : . ::...* : :: : .:..* * . : :. . . *: : :*. . : .: : . : :: : :: . : : * : : . : : :. .*: : . : ::: ..: * . :::*. : :::: * :**:** . . : **.:. * :: *.: :. *:*::: . .. . * .:* : .. :* : : : : :* .:: . **. . ..:: * ::.: : * .*: .: * : * :* .* . : : * :. *:::.:: . . : . ***.*:* *:.. : .:: . ", "identical_positions": 73, "similar_positions": 314, "identity": "3.72%" }, { "cls_id": "homologset.agr.FB:FBgn0011204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07522-1", "uniprot_id": "EGF_RAT", "id": "P07522-1", "name": "Pro-epidermal growth factor", "aln": "-------MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTTTYAAAGPPRFLIFLQGNSIFRINTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVSGLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSVVTGNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYNGGSIHHIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVHLHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSSACAEGYTLSRDRKYCEDVNECALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGPLCICPAGSVLGKDGKTCTGCSFSDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAASMGPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANLDGSQRERRITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISRPRGIAVHPKARRLFWTDTGMS-PRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWCDTKL---SVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRVRLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKMCLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESSTLVAEIMVSGLNYEDDCGPGGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGY-VCQCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSPSLLGKDGCHWVRNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLRHADYGQRHDITVVSVCVVALALLLLLG---MWGTYYYRTRKQLSESSKKPSEESSSNVSSNGPDSS-GAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01132-1", "uniprot_id": "EGF_MOUSE", "id": "P01132-1", "name": "Pro-epidermal growth factor", "aln": "MPWGRRPTWLLLAFLLVFLKISILSVTAWQTGNCQPGPLERS-ERSGTCAGPAPFLVFSQGKSISRIDPDGTNHQQLVVDAGISADMDIHYKKERLYWVDVERQVLLRVFLNGTGLEKVCNVERKVSGLAIDWIDDEVLWVDQQNGVITVTDMTGKNSRVLLSSLKHPSNIAVDPIERLMFWSSEVTGSLHRAHLKGVDVKTLLETGG-ISVLTLDVLDKRLFWVQDSGEGSHAYIHSCDYEGGSVRLIRHQARHSLSSMAFFGDRIFYSVLKSKAIWIANKHTGKDTVRINLHPSFVTPGKLMVVHPRAQPRTEDAAKDPDPELLKQRGRPCRFGLCERDPKSHSSACAEGYTLSRDRKYCEDVNECATQNHGCTLGCENTPGSYHCTCPTGFVLLPDGKQCHELVSCPGNVSKCSHGCVLTSDGPRCICPAGSVLGRDGKTCTGCSSPDNGGCSQICLPLRPGSWECDCFPGYDLQSDRKSCAAS-GPQPLLLFANSQDIRHMHFDGTDYKVLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANMDGSQRERLITEGVDTLEGLALDWIGRRIYWTDSGKSVVGGSDLSGKHHRIIIQERISRPRGIAVHPRARRLFWTDVGMS-PRIESASLQGSDRVLIASSNLLEPSGITIDYLTDTLYWCDTKR---SVIEMANLDGSKRRRLIQNDVGHPFSLAVFEDHLWVSDWAIPSVIRVNKRTGQNRVRLQGSMLKPSSLVVVHPLAKPGADPCLYRNGGCEHICQESLGTARCLCREGFVKAWDGKMCLP-QDYPILSGENADLSKEVTSLSNSTQAEVPDDDGTESSTLVAEIMVSGMNYEDDCGPGGCGSHARCVSDGETAECQCLKGFARDGNLCSDIDECVLARSDCPSTSSRCINTEGGY-VCRCSEGYEGDGISCFDIDECQRGAHNCGENAACTNTEGGYNCTCAGRPSSPGLSCPDSTAPSLLGEDGHHLDRNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELRHAGYGQKHDIMVVAVCMVALVLLLVLG---MWGTYYYRTRKQLSNPPKNPCDEPSGSVSSSGPNSSSGAAVASCPQPWFVVLEKHQDPKNGSLPADGTNGAVVDAGLSPSLQLGSVHLTSWRQKPHIDGMGTGQSCWIPPSSDRGPQEIEGNSHLPSYRPVGPEKLHSLQSANGSCHERAPDLPRQTEPVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q95RU0-1", "uniprot_id": "CUE_DROME", "id": "Q95RU0-1", "name": "Protein cueball", "aln": "-------------------------------------------------------------------------------------MIRIRFGMDVLLVLLLATCLLT-----------------PAHGTPLEWDFAVTLRTK-----IQFMDSSWQTIATAAHEFDELSALTFDESEELIYFN---------------------------------------------------------------------------------------------------------------------------------------------DLKHRNG-------------------SIFSLKRDLIAANHVAEQTIARTGNES-------------------------------------------------------------------------------------------------------------------------------------------------VGGLAYDPLNMNLFWSDTEQRKIFFAPIHGSATPQVLVD----------------------------------------LSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDAIYWTDRTTRAVWSHPKVPVIKVTTTSKPDEEDSTDSTDFKDPEPVAEDCPLVR--VANLSEEARG---IVARTGFYQR-------------------LQKDHHCASIVRKVKERVDEQSRKFEIRSLLDQKIKVLEDERCMNDGEYR--------AATDLCICPTGFKGS--------RCEIRECHNYCVHGTCQMSELAYPKCYCQPGFKGE---RCELSVCSGLCLNGGHCRVSKDENEAPSCECPAKFG--GARCEQNST------EICSLFCRLLKHEPEMYVPFGCHSICEELAQDNSTNIAIPQYQHLEVCLTPRVWTSSVIIILVVGIVSSLLLVAVIVQGIRRLYKPKRPRIRKTFVVRKQARTNSAGDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQTLSKSSCKEDKK---ILIHNMEDDLY-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: : * : : :* . * .::* * .. * . * . :. . .:.. : : .* *.*:::. *:* . ::*.** .:.* * : . * * .* ***:: ::::::* : * * :.** : :.: :. .** *:**. *:*:**: .:: * :* .*:**:*.:* ***: * **.:* *:* *:* * :* :.****.*: : ::. .*:.*** :* :: :* : :* * . : . . : *: . . .:* *: * . ::.:*: * :.* ** : : .:. :*: .. : * ::. . . : : :. :: * . * . : * * .** . .* : .. . . * :* .* * *. *::*: ::. *. . . .. ...: : . .* *.. . * * :.:: : . * * : :. :. . . : * : * .: :*:* : .: * : *: *.: : ... ..* : . ... . . : * * .* .:. . :: .:. .* ", "identical_positions": 114, "similar_positions": 223, "identity": "9.28%" }, { "cls_id": "homologset.agr.FB:FBgn0011206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NR90-1", "uniprot_id": "DAZ3_HUMAN", "id": "Q9NR90-1", "name": "Deleted in azoospermia protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT---------GCQLLVYNYQEYPTYPDSAFQ---------------------------------VTTGYQLPVYN-------------------------------------YQPFPAYPRSPFQVTAGYQLP---------------VYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNS------------------------------------------------------------------------PFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13117-1", "uniprot_id": "DAZ2_HUMAN", "id": "Q13117-1", "name": "Deleted in azoospermia protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT---------GCQLLVYNYQEYPTYPDSAFQ---------------------------------VTTGYQLPVYN-------------------------------------YQPFPAYPRSPFQVTAGYQLP---------------VYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86SG3-1", "uniprot_id": "DAZ4_HUMAN", "id": "Q86SG3-1", "name": "Deleted in azoospermia protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQS-AANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSS------------------------------------------------------------------------PFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NQZ3-1", "uniprot_id": "DAZ1_HUMAN", "id": "Q9NQZ3-1", "name": "Deleted in azoospermia protein 1", "aln": "MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQS-AANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSS------------------------------------------------------------------------PFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JYV3-1", "uniprot_id": "A0A0G2JYV3_RAT", "id": "A0A0G2JYV3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSATTSEAPNS-----AVSREASTQSSSATTSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVES--QINFHGKKLKLGPAIRKQNLCTYHVQPRPLIFNPPPPPQFQSVWSSPNAETYMQPPTMMNPITQYVQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPPYPSSPVQVITGYQLPVYNYQMPPQWP-------AGEQR---SYVIPPAYT-------------TVNYHCSEVDPGA------------------------------------------------------------------------------------------DLLPN-----------ECSVHDAAPASGNGPQKKSVDRSIQTVVSCLFN--PENRLRNSLVTQDDYFKDKRVHHFRRSRAVLKSDHLC--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64368-1", "uniprot_id": "DAZL_MOUSE", "id": "Q64368-1", "name": "Deleted in azoospermia-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSATTSEAPNS-----AVSREASTQSSSATTSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVES--QINFHGKKLKLGPAIRKQNLCTYHVQPRPLIFNPPPPPQFQSVWSSPNAETYMQPPTMMNPITQYVQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPPYPSSPVQVITGYQLPVYNYQMPPQWP-------AGEQR---SYVIPPAYT-------------TVNYHCSEVDPGA------------------------------------------------------------------------------------------DILPN-----------ECSVHDAAPASGNGPQKKSVDRSIQTVVSCLFN--PENRLRNSLVTQDDYFKDKRVHHFRRSRAVLKSDHLC--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92904-1", "uniprot_id": "DAZL_HUMAN", "id": "Q92904-1", "name": "Deleted in azoospermia-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTANPETPNS-----TISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVES--QINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPTYPNSPVQVITGYQLPVYNYQMPPQWP-------VGEQR---SYVVPPAYS-------------AVNYHCNEVDPGA------------------------------------------------------------------------------------------EVVPN-----------ECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFN--PENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGW7-1", "uniprot_id": "DAZL_DANRE", "id": "Q9YGW7-1", "name": "Deleted in azoospermia-like", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQGVQLPVCLICGLYSQDIQKHRQGFPSSLKLSNGYILPEGKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKGYGFVYFSEDVDIQTIVDQ--PISFKGKKLKLGPAIMKERSSRSVSSP---MIGP-------SQWVNPTPYMYCS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCPPGLAPPSPVFSGGNQ----YMQP------------------------------------------YSYSSPPG-------------------------------------------------------------------------------------------------------------------IMVPQVPMNYAQTTYAYQYPLPQWCGEQ-------RTRLVNQN----------FVDCGVQTLLTLM---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N9W6-1", "uniprot_id": "BOLL_HUMAN", "id": "Q8N9W6-1", "name": "Protein boule-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTDS------LSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPPWPSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVCSSPVMVAQPIYQQPAYHYQATTQYLPG-----------------------------------QWQWSVPQPSASS----------------------------------------------------------------------------------------------------------APFLYLQPSEVIYQPVEIAQDGGCVPPPLSLMETSVPEPYSDHGVQATYHQ--------VYAPSAITMPAPVMQPE-PIKTVWSIHY-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q924M5-3", "uniprot_id": "BOLL_MOUSE", "id": "Q924M5-3", "name": "Protein boule-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------METESRAQSTNQTQTDS------LSPSPNPVSPVPLNNPTSGPRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFITFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSLMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPSWPSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SISSSPVMVAQPVYQQPAYHYQAPAQCLPG-----------------------------------QWQWGVPQSPASS----------------------------------------------------------------------------------------------------------APFLYLQPSEVIYQPVEIAQDGGCVPPPLSLMETSVPEPYSDHGVQAAYHQ--------VYASSAIAMPAPMMQPE-PIK-VRSLF------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6M1-1", "uniprot_id": "A0A0G2K6M1_RAT", "id": "A0A0G2K6M1-1", "name": "Protein boule-like", "aln": "----------------------------------------------------------------------------------------------GFPPPLLAGLPDKISRWLAFFSLPHFGGEGGDPRVSVPVHDDPREPEDVVNCPITSACWPQRGRSTEAVTATQTTNQTQTDS------LSPSPNPVSPVPLNNPTSGPRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFITFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPSWPSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SISSSPVMVAQPVYQQPAYHYQAPAQCIPG-----------------------------------QWQWGVPQSPASS----------------------------------------------------------------------------------------------------------APFLYLQPSEVIYQPVEIAQDGGCVPPPLSLMEASVPEEPRLHSVRRSFSQPSSVGLKPRYSRSPHFHPRKDFRAEDSVSTPPSCTDFVK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24207-1", "uniprot_id": "BOULE_DROME", "id": "Q24207-1", "name": "Protein boule", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHKIA------AAPPPSATPGGGLETPLAAPKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKGYGFVTFETEQEAQRLQADGECVVLRDRKLNIAPAIKKQPN--PLQSIVATNGAVYYTTTP--------------PAPISNIPMDQFAA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVYP-PAAGVPAIYPPSAMQYQPFYQYYS-----------------------------------------VPMN--------------------------------------------------------------------------------------------------------------VPTIWPQNYQENHSP---------------LLHSPTSNPHSPHSQSHPQSP--------CWSIEDLRDTLPRV-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . *.: ** :*****. * :: *. **:**..**: * *:.*****: * : : * : . : :.:**::.*** *: . . . . . * . ", "identical_positions": 32, "similar_positions": 36, "identity": "3.88%" }, { "cls_id": "homologset.agr.FB:FBgn0011207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIP1-1", "uniprot_id": "PELO_RAT", "id": "Q5XIP1-1", "name": "Protein pelota homolog", "aln": "--MKLVRKDIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLR---VKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKG-NCSQHDRALERFYEQVVQAIQRHINFEVVKCILVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEVLCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDD----------SSSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X73-1", "uniprot_id": "PELO_MOUSE", "id": "Q80X73-1", "name": "Protein pelota homolog", "aln": "--MKLVRKDIEKDNAGQVTLVPEEPEDMWHTFNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLR---VKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKG-NCSQHDRALERFYEQVVQAIQRHINFEVVKCVLVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDD----------SSSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX2-1", "uniprot_id": "PELO_HUMAN", "id": "Q9BRX2-1", "name": "Protein pelota homolog", "aln": "--MKLVRKNIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLR---VKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHICLVTPSMTLTRAKVEVNIPRKRKG-NCSQHDRALERFYEQVVQAIQRHIHFDVVKCILVASPGFVREQFCDYLFQQAVKTDNKLLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLSQLTGVAAILRFPVPELSDQEGD----------SSSEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWC4-1", "uniprot_id": "PELO_DANRE", "id": "Q7ZWC4-1", "name": "Protein pelota homolog", "aln": "--MKLVHKDIEKDNAGQVTLIPDEAEDMWHTYNLLQVGDSLRASTIRKVQTESSTGSVGSSRVRTTLTLCVETIDFDSQACQLR---VKGTNIQENQYVKMGAYHTIELELNRKFTLAKKVWDSVVLDRIEQACDPAQKADVAAVVMQEGLANLVLVTPAMTLLRAKVEVTIPRKRKG-SCTQHDKALERFYEAVMQGILRHFNFDVVKCILVASPGFVKDQFISYLFKEAVRQDCKLLLENRSKFMVVHSSSGHKYSLKEVLCDPAVTARLSDTKAAGEVKALEDFYKMLQQEPDRAFYGLAHVERASEALAIDILLISDTLFRHQDVATRGRYVRLVDNVKENGGTVRIFSSLHVSGEQLNQLSGVAAILRFPIADVSEPEEN----------SSSDED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48612-1", "uniprot_id": "PELO_DROME", "id": "P48612-1", "name": "Protein pelota", "aln": "--MKLLGKYVDKGMQGNVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTLTIAVESIDFDTQACVLR---LKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACDPTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRKRKG-SVQQHEKGLAKFYEQVMQSILRHVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDPAVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSLRKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDDDDEDGAAGGVADSDSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q96VH2-1", "uniprot_id": "YC01B_YEAST", "id": "Q96VH2-1", "name": "Putative pelota-like protein YCL001W-B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDFLEHLSKDDNKAWYGAEETERAAKLDAIETLLITDSVLKRNDVKKREKYLDLIENSGNNNGKIFVLSTS-----------------KITVSNLTNQQI-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33309-1", "uniprot_id": "DOM34_YEAST", "id": "P33309-1", "name": "Protein DOM34", "aln": "MKVISLKKDSFNKGGAVITLLPEDKEDLFTVYQIVDKDDELIFKKKFTSKLDEAGKKKSTDLVKLKIKVISEDFDMKDEYLKYKGVTVTDESGASNVDIPVGKYLSFTLDYVYPFTIIKQNFNKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSSSTILKQKIEYSMPKKKRTTDVLKFDEKTEKFYKAIYSAMKKDLNFDKLKTIILCSPGFYAKILMDKIFQYAEEEHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNKDDDKAWYGEKEVVKAAEYGAISYLLLTDKVLHSDNIAQREEYLKLMDSVESNGGKALVLSTLHSLGEELDQLTGIACILKYPLPDLDEDDGEE---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* *. : :*:** .. :* : **. **::* ::: ::: * .*: *::. . * ::*: : .:.:: : : ", "identical_positions": 16, "similar_positions": 37, "identity": "3.99%" }, { "cls_id": "homologset.agr.FB:FBgn0011211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15999-1", "uniprot_id": "ATPA_RAT", "id": "P15999-1", "name": "ATP synthase F(1) complex subunit alpha, mitochondrial", "aln": "--MLSVRIAAAVARALPRRAGLVS-KNALGSSFVGTRNLHASNTRLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGPVGSKIRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFESAFLSHVVSQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03265-1", "uniprot_id": "ATPA_MOUSE", "id": "Q03265-1", "name": "ATP synthase F(1) complex subunit alpha, mitochondrial", "aln": "--MLSVRVAAAVARALPRRAGLVS-KNALGSSFVGARNLHASNTRLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDVVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVISQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25705-1", "uniprot_id": "ATPA_HUMAN", "id": "P25705-1", "name": "ATP synthase F(1) complex subunit alpha, mitochondrial", "aln": "--MLSVRVAAAVVRALPRRAGLVS-RNALGSSFIAARNFHASNTHLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGFEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35381-1", "uniprot_id": "ATPA_DROME", "id": "P35381-1", "name": "ATP synthase subunit alpha, mitochondrial", "aln": "MSIFSARLASSVARNLPKAANQVACKAAYPAASLAARKLHVAST--QRS--AEISNILEERILGVAPKADLEETGRVLSIGDGIARVYGLNNIQADEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKQGDIVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGAINTKDRFRVGIKAPGIIPRVSVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTALAIDTIINQKRFNEAQDESKKLYCIYVAIGQKRSTVAQIVKRLTDSGAMGYSVIVSATASDAAPLQYLAPYSGCAMGEYFRDKGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPAMGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAGSMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEDQVAVIYCGVRGHLDKMDPAKITKFEKEFLQHIKTSEQALLDTIAKDGAISEASDAKLKDIVAKFMSTFQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07251-1", "uniprot_id": "ATPA_YEAST", "id": "P07251-1", "name": "ATP synthase subunit alpha, mitochondrial", "aln": "--MLAR---TAAIRSLSRTLINST-KAARPAAAALASTRRLASTKAQPT---EVSSILEERIKGVSDEANLNETGRVLAVGDGIARVFGLNNIQAEELVEFSSGVKGMALNLEPGQVGIVLFGSDRLVKEGELVKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDAAGRSRAQVKAPGILPRRSVHEPVQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNNGSDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEAAPLQYLAPFTAASIGEWFRDNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLVRGERLTQLLKQNQYSPLATEEQVPLIYAGVNGHLDGIELSRIGEFESSFLSYLKSNHNELLTEIREKGELSKELLASLKSATESFVATF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: ::. * *.: : : * :: : . : :.* * : *:*.****** *. ..:*:******::*******.**.*:**:*:******:***:*****.:**:*:**.*:*:*:*::***** ******* ***********.*****.:.: * *. :*****:** **:**:***:****:*********************::*:***:****:*:. **.*****:***:*********:*: * : .** *:::*:****:*********::..::**:***:******:*************:******************************:. *.************.**********************:*************************.:*:*****::** *******************:*:* * ** ***:****.** *:* *:**.:**.**.*:** :: ::* :**. **.:: :..: ** * .* :*: *.**. . .*:: * ", "identical_positions": 355, "similar_positions": 128, "identity": "63.85%" }, { "cls_id": "homologset.agr.FB:FBgn0011217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15732-1", "uniprot_id": "UBC5_YEAST", "id": "P15732-1", "name": "Ubiquitin-conjugating enzyme E2-16 kDa", "aln": "-------MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P15731-1", "uniprot_id": "UBC4_YEAST", "id": "P15731-1", "name": "Ubiquitin-conjugating enzyme E2 4", "aln": "-------MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P61080-1", "uniprot_id": "UB2D1_MOUSE", "id": "P61080-1", "name": "Ubiquitin-conjugating enzyme E2 D1", "aln": "--------MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51668-1", "uniprot_id": "UB2D1_HUMAN", "id": "P51668-1", "name": "Ubiquitin-conjugating enzyme E2 D1", "aln": "--------MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZDK2-1", "uniprot_id": "UB2D1_RAT", "id": "D3ZDK2-1", "name": "Ubiquitin-conjugating enzyme E2 D1", "aln": "--------MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2X8-1", "uniprot_id": "UB2D4_HUMAN", "id": "Q9Y2X8-1", "name": "Ubiquitin-conjugating enzyme E2 D4", "aln": "--------MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWTQKYAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62839-1", "uniprot_id": "UB2D2_RAT", "id": "P62839-1", "name": "Ubiquitin-conjugating enzyme E2 D2", "aln": "--------MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62838-1", "uniprot_id": "UB2D2_MOUSE", "id": "P62838-1", "name": "Ubiquitin-conjugating enzyme E2 D2", "aln": "--------MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62837-1", "uniprot_id": "UB2D2_HUMAN", "id": "P62837-1", "name": "Ubiquitin-conjugating enzyme E2 D2", "aln": "--------MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70711-1", "uniprot_id": "U2D2B_RAT", "id": "P70711-1", "name": "Ubiquitin-conjugating enzyme E2 D2B", "aln": "--------MALKRIHKELNDLAQDPPAQCSAGPVGEDMFHWQATIMGPNDSPYQGGAFFLTIDFPTEYPFKPPKVEFTTRIYHPNVNSNGSICLDILRSQWSPALTISKVLLSISSLLCDPNPDDPLVPEIAQIYKTDRDKYNRTAREWTQKYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWY6-1", "uniprot_id": "U2D2B_MOUSE", "id": "Q6ZWY6-1", "name": "Ubiquitin-conjugating enzyme E2 D2B", "aln": "--------MALKRIHKELNDLAQDPPAQCSAGPVGEDMFHWQATIMGPNDSPYQGGAFFLTIDFPTEYPFKPPKVEFTTRIYHPNVNSNGSICLDILRSQWSPALTISKVLLSISSLLCDPNPDDPLVPEIAQIYKTDRDKYNRTAREWTQKYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61077-1", "uniprot_id": "UB2D3_HUMAN", "id": "P61077-1", "name": "Ubiquitin-conjugating enzyme E2 D3", "aln": "--------MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61078-1", "uniprot_id": "UB2D3_RAT", "id": "P61078-1", "name": "Ubiquitin-conjugating enzyme E2 D3", "aln": "--------MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61079-1", "uniprot_id": "UB2D3_MOUSE", "id": "P61079-1", "name": "Ubiquitin-conjugating enzyme E2 D3", "aln": "--------MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25867-1", "uniprot_id": "UBCD1_DROME", "id": "P25867-1", "name": "Ubiquitin-conjugating enzyme E2-17 kDa", "aln": "--------MALKRINKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNELAREWTRKYAM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6GLC9-1", "uniprot_id": "A0A8I6GLC9_RAT", "id": "A0A8I6GLC9-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "--------MALKRIEKELLDLARDPPTQCSAGPVGEDMFHWQATIMGPDDSPYQGGVFFLAIHFPTDYPFKPPKITFTTRIYHPNINRKGSICLDILRSEWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAKIYRKDKKKYDRLAREWTEKFAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AFH2-1", "uniprot_id": "A2AFH2_MOUSE", "id": "A2AFH2-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "MDQSTLGAMALKRIQKELVAISQDPPAHCSAGPVAENMFHWQATIMGPEDSPYQGGVFFLSVHFPNNYPFKPPKVTFITRVYHPNISKNGSICLDILNSMWSPALTISKLLLSICSLLCDPNPDDPLVPEIAKVYRKDLREYNRLAREWTKRYAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AFH1-1", "uniprot_id": "A2AFH1_MOUSE", "id": "A2AFH1-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "MVQPSLGAMALKRIQKELVAFSQDPPAHCSAGPVAENMFHWQATIMGPEDSPYQGGVFFLSIHFPNNYPFKPPKVSFITRIYHPNISKNGSICLDILNSKWSPTLTISKVLLSICSLLCDPNADDPLVPEIAKVYHKDLREYNRLAREWTERFAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZL88-1", "uniprot_id": "D3ZL88_RAT", "id": "D3ZL88-1", "name": "", "aln": "MVHPTLEEMALKRIQKELVAFSQDPPAQCSAGPVAENLFHWQATIMGPEDSPYQGGVFFLSVHFPSNYPFRPPKVSFITRIYHPNISKNGSICLDILNSEWSPALTISKVLLSICSLLCDPNPDDPLVPEIAKVYRKDLKQYDRMAREWTERYAM", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** *** : :***: ******.::::****:**** **.* **.***::.**.:***:***: * *::****:. .*.******.. ***:**:**:****.*** *.*.******:**: *: * :*: ::***.::*:", "identical_positions": 83, "similar_positions": 44, "identity": "53.55%" }, { "cls_id": "homologset.agr.FB:FBgn0011224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17225-1", "uniprot_id": "PTBP1_MOUSE", "id": "P17225-1", "name": "Polypyrimidine tract-binding protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSS-SAS--AANGND-----SKKFKGDNRSAGV-----PSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQ---------AR---------------------------AQAALQAVNSVQSGN--LALAASAAAVDAG---MAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPS--LDQTMAAAFGAPGIMSASPYAGAG----FPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAS---------------RIAIPGLAG---------AGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00438-1", "uniprot_id": "PTBP1_RAT", "id": "Q00438-1", "name": "Polypyrimidine tract-binding protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSS-SAS--AANGND-----SKKFKGDNRSTGV-----PSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMSTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQ---------AR---------------------------AQAALQAVNSVQSGN--LALAASAAAVDAG---MAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPS--LDQTMAAAFGAPGIMSASPYAGAG----FPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAG--------------RIAIPGLAG---------AGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26599-3", "uniprot_id": "PTBP1_HUMAN", "id": "P26599-3", "name": "Polypyrimidine tract-binding protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSAS--AANGND-----SKKFKGDSRSAGV-----PSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQ---------AR---------------------------AQAALQAVNSVQSGN--LALAASAAAVDAG---MAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPS--LDQTMAAAFGAPGIISASPYAGAG----FPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAG--------------RIAIPGLAG---------AGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZR32-1", "uniprot_id": "A0A8I5ZR32_RAT", "id": "A0A8I5ZR32-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANGND-----SKKFKGDNRSTGV-----PSRVIHVQKLPSNVTEGKVISLELPFGNVTNLLMLKGKNQASIEMSTEEAANTMVNYYTWVAPVLHGQPIYIQFSNHKEFKTHSSPNQ---------AR---------------------------AQAALQAVNSVQSGN--LALAASAAAVDAG---MAKAGQRPVIRFIVENLFYPVTLDALHQIFSKFG------------AFQVLLQHADPVSAQHAKLSLDGQNIYNACCTLHINFSKLTSLDVKYNNDKSRDYTRPALPSGD-------------IFFVPGITSDSPNAGAG----FPLTFATPQAAGLSVPNVHGALATLAIP--SAAVAAAG--------------RIAIPGLAG---------VGNSILLVSNLNPERVTAQSLFILFSIYGDVKRMKILFNKKENALLQMADGNQAQLAMSHLNGHKLDGKSVRITPSKHQSVQLPHERQEDQGLTKNYDSSPLHCVQKPGSKNFQNIFPPSATLHLSNIPPSVSEDGLKSLFSSNGDMAKGFKFFKKDHKMALIQMGSVEEAVQALIELHSHDLGENYHPRVFFSKSTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XZ1-1", "uniprot_id": "Q80XZ1_RAT", "id": "Q80XZ1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRNSPP--AAEGNG-----SKRFKGDSWGTRD-----PSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGT--VALAPPASAVDTE---LVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIA----LPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z118-1", "uniprot_id": "PTBP3_RAT", "id": "Q9Z118-1", "name": "Polypyrimidine tract-binding protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNSTSAGVYANGND-----NKKFKGD-RPPCS-----PSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQ---------AR---------------------------AQAALQAVSAVQSGN--LSLPG-ATSNEGT---LLPG-QSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPS--LEPPMAAAFGAPGIMS-SPYAGAAG---FAPAIAFPQAAGLSVSAVPGALGPLTLT----SSAVSG--------------RMAIPGASG--------IPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHD7-1", "uniprot_id": "PTBP3_MOUSE", "id": "Q8BHD7-1", "name": "Polypyrimidine tract-binding protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSSTSAGVYANGND-----NKKFKGD-RPPCS-----PSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQ---------AR---------------------------AQAALQAVSAVQSGN--LSLPG-ATANEGT---LLPG-QSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPS--LEPPMAAAFGAPGIMS-SPYAGAAG---FAPAIAFPQAAGLSVPAVPGALGPLTLT----SSAVSG--------------RMAIPGASG--------MPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95758-3", "uniprot_id": "PTBP3_HUMAN", "id": "O95758-3", "name": "Polypyrimidine tract-binding protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVVTDLITVGLKRGSDELLSSGIINGPFTMNSSTPS--TANGND-----SKKFKRD-RPPCS-----PSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQ---------AR---------------------------AQAALQAVSAVQSGS--LALSG-GPSNEGT---VLPG-QSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPS--LEPPMAAAFGAPGIIS-SPYAGAAG---FAPAIGFPQATGLSVPAVPGALGPLTIT----SSAVTG--------------RMAIPGASG--------IPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB37-1", "uniprot_id": "E7FB37_DANRE", "id": "E7FB37-1", "name": "Polypyrimidine tract-binding protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSTPS-TTANGTD-----SKQYKGD-RSPCA-----PSRVLHVRKVPIEVSEAEVVSLGVPFGKVTNLLMLKGKNQAFIEMASEEAAMTMVNYYTTATPHVRNQPVYIQYSNHRELKTDNLPNQ---------GR---------------------------AQAALQAVNAVHTGN--MSLSGTATASDGG---MMPG-QSPVLRIIVENLYYPVSLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMNAHHAKVALDGQNIYNGCCTLRVEFSKLTSLNVKYNNDKSRDFTRLDLPSGDGQPT--LDPTMQTAFGAPGIIS-SPYPGAAG---FAPAIGFPQAG-LSMQAMPGALGPLTIP----SSAMTG--------------RMAIHGMTP--------TAIHSVLLVSNLNPDSISPHELFILFGVYGDVHRVKILFNKKENALIQMADATQAQLAMSHLNGQRLYGKVIRVTISKHQTVQLPREGQEDQGLTKDFSGSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSTTDDFLKDLFASSGYTVKAFKFFQKDRKMALIQLGSVEEAIQALIHLHNHDLGENHHLRVSFSKSTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q66H20-1", "uniprot_id": "PTBP2_RAT", "id": "Q66H20-1", "name": "Polypyrimidine tract-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVTEVAVGVKRGSDELLSGSVLSSP--NSNMSGMVVTANGND-----SKKFKGEDKMDGA-----PSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQ----------R---------------------------AQVVLQAVTAVQTAN--TPLSG--TTVSES---AVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPA------------------------------LDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAG------------RVGMPGVSAG---------GNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQ-DHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z31-1", "uniprot_id": "PTBP2_MOUSE", "id": "Q91Z31-1", "name": "Polypyrimidine tract-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVTEVAVGVKRGSDELLSGSVLSSP--NSNMSGMVVTANGND-----SKKFKGEDKMDGA-----PSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQ----------R---------------------------AQVVLQAVTAVQTAN--TPLSG--TTVSES---AVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPA------------------------------LDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAG------------RVGMPGVSAG---------GNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQ-DHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKA9-1", "uniprot_id": "PTBP2_HUMAN", "id": "Q9UKA9-1", "name": "Polypyrimidine tract-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVTEVAVGVKRGSDELLSGSVLSSP--NSNMSSMVVTANGND-----SKKFKGEDKMDGA-----PSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQ----------R---------------------------AQAVLQAVTAVQTAN--TPLSG--TTVSES---AVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPA------------------------------LDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAG------------RVGMPGVSAG---------GNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQ-DHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6W9-1", "uniprot_id": "A0A0B4K6W9_DROME", "id": "A0A0B4K6W9-1", "name": "", "aln": "MMSCPIPMPMPISSLHKSEFEPVNIGVKQMQLLHAPASTHPHPHPHQHPQHSAASAAAYQAMQVHQQQHQQQQQAAVFHHQVAAIAAQQQQQQQQAQVQHQQQMQQQFHYQAQAQAQAQAMLQTYMQLQVNSAVGVSTAPATPTKPVAAQIPGAISGPIAGPVPVSVPTQFFTAPSTPLTIIPAAAVASSAMFATAATPTSAATTPTNNVNNTVNLSAVSRTTTTTTKKQPQAVADAVLSAVGGNVGTAVGGGTISSLLGPEPLPIMPHHLPLASVRGCSSASSGCSSASSDCSMPSPTSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAAVMAPASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSP---------------LPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGA-------------LQTTAPAMRG----------YSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.... .*: * : .*:::*: .:* * .::.* :***.*:*:*.*:.*.** :*: * :* :*:. *: .* ::.: :::*:::::*:*. . .: *: : .. : .: . .*:*.:::. * *:*: *****.::* **.*:*: . .*. ** *******:.****::. * *. * **********: . **..: . . * . . . . :***:*** : ::. ** **. ****:*:**::*:*:.**:***: *: :*: **. :: ** : **** *:**:* * ***::: .*** .:******:***:**********:*. : : :: * . . .*.*:** ::****::: :.***: **:.:*.: *.:. * ** **: .*", "identical_positions": 160, "similar_positions": 156, "identity": "17.09%" }, { "cls_id": "homologset.agr.FB:FBgn0011225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZWC2-1", "uniprot_id": "A0A8I5ZWC2_RAT", "id": "A0A8I5ZWC2-1", "name": "Unconventional myosin-VI", "aln": "-MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNVKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSDTIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPE---YVKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAG-STSGGCNLKNKSAPSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANSARDALAKTVYSHLFDHVVDRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEVKLVGILDILDEENRLPQPSDQHFTSVVHQKHKDHFRLTIPRKSKLAVHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRALFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFKALGLNEVDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSALKDGKPEVNRQIKDLEISIDALMAKIKS-TMMTREQIQKEYDALVKSSEDLLSALQ---KKKQQEEEAERLRRIQEEMEKERKRREEDEQRRRKEEEERRMKLEMEVKRKQEEEERKKREDDEKRIQAEVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQGDTALR--------------------------------RGPAVQATKAAAGTKKHDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETE-QRAPKSVTDYD-FAPFLNNSPQQNPAAQLPA-RQQEIEMNRQQRFFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQSAIESRQARPTYATAMLQNLLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64331-1", "uniprot_id": "MYO6_MOUSE", "id": "Q64331-1", "name": "Unconventional myosin-VI", "aln": "-MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNVKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSDTIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRFFANKETDKQILQNRKSPE---YVKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAG-STSGGCNLKNKSAPSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEVKLVGILDILDEENRLPQPSDQHFTSVVHQKHKDHFRLTIPRKSKLAVHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRALFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFKALGLNEVDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSALKDGKPEVNRQIKNLEISIDALMAKIKS-TMMTREQIQKEYDALVKSSEDLLSALQ---KKKQQEEEAERLRRIQEEMEKERKRREEDEERRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQGDMALR--------------------------------RGPAVQATKAAAGTKKHDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETE-QRAPKSVTDYD-FAPFLNNSPQQNPAAQLPA-RQQEIDMKRQQRFFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQSAIESRQARPTYATAMLQNLLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UM54-3", "uniprot_id": "MYO6_HUMAN", "id": "Q9UM54-3", "name": "Unconventional myosin-VI", "aln": "-MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPE---YLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAG-STSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKS-TMMTQEQIQKEYDALVKSSEELLSALQ---KKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRSLDSYPVSKNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETE-QRAPKSVTDYD-FAPFLNNSPQQNPAAQIPA-RQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQNAIESRQARPTYATAMLQSLLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N1X8-1", "uniprot_id": "A0A8M1N1X8_DANRE", "id": "A0A8M1N1X8-1", "name": "Unconventional myosin-VI", "aln": "-MDDGKLVWAPHPTDGFQLGMIVDIGADALTIEPLHQRGKTFLAPISQVFPAEDDVNKHVEDNCSLMYLNEATLLNNIRIRYSKDMIYTFVANILIAVNPYFDIPKLYSPESIKSYQGRSLGTLPPHVYAIADKAYRDMRVLKMSQSIIVSGESGAGKTENTKFVLRYLTTSYGTGQDIDERIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKNAVVGGFVSHYLLEKSRICMQSQEERNYHIFYRLCAGASEDIRNMLHLNSPDSFRYLNRGCTRYFANKDSDKQIMQNXKSPEDHKHGKVGALKDPLLDDLGDFNRMVVAMKKIGLDDTEKLNLFRVVAGVLHLGNIDFEETG-STSGGCILKNQSSQTLEYCADLLGLDQDDLRVSLTTRVMLTTAGGAKGTVIKVPLKVEQANNARDALAKAVYSRLFDHVVKRVNQCFPFDTSSNFIGVPDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQREGLGVNEVHYVDNQDCIDLVEAKLVGVLDILDEENRLPQPSDQHFAEAVHSKHKDHFRLTVPRKSKLTIHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLVCESKDKFVRDLFENNSNS-KDSKQKAGKLSFISVGNKFKTQLNLLLEKLRSTGSSFIRCVKPNLKMVSHQFEGAQILSQLQCSGMVSVLDLMQGGFPSRAPFHELYNMYKQYMPNKLTRLDPRLFCKALFKALGLNENDYKFGLTRVFFRPGKFAEFDQIMKSDPDHLAELVKRVNKWLVCSRWKKVQWCTLSVIKLRNKMSYRASACIRIQKTVRMWLCRRRHKPRVDGLVKVKNLRKRMERFNEAVNGLKEGKAEMSKQIEELAASTDALMAKIKT-TVMSRKEIEQEYEGLVKRSEQLLSSMQ---KKKQEQEETERLKHIQEEMEKERKRHEEEEQLRKQEEEDRRMKSEMEQKRKQEEEERKKREEEERVLQAELEMQLALDREEETQRQTILEQERRDRELAMRIAQNEAELIQDEAQMDPILRRDATTG--------------------VWFFTEMGAQVQANKVAAGVKKYDLSKWKYAELRDAINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTDTE-MRAPKSVTDY----------AQQNPAPPVPA-RQQEIAMNRQQRYFRIPFIRPADQYKDPQNKKKGWWYAHFDGPWIARQMELHPDKQPILLVAGKDDMEMCELSLEETGLTRKRGAEILPRQFEEIWERCGGIQYLKNAIESKQARPTYATAMLQNLLK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PH95-1", "uniprot_id": "A0A8M9PH95_DANRE", "id": "A0A8M9PH95-1", "name": "Unconventional myosin-VI", "aln": "-MDDGKPVWAPHPTDGFQLGRIIDISADSLTIEPLNQRGKNFQAPVDQVFPAEDDVNKHVEDNCSLMYLNEATLLNNVRVRYSKDKIYTFVANILIAVNPYCEIPKLYSPETIKQYQGRSLGTLPPHVYAIADKAYRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTTSYGTGQDIDERIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKNAVVGGFVSHYLLEKSRICTQGQEERNYHIFYRLCAGAPEDIREKFHLSSPDCFRYLCRGCTRYFSTKDSDKLIPQNRKSPE---LLKAGPLKDPLLDDHADFNRMSVAMKKIGLDDTEKLNLFRVVAGVLHLGNIDFEEAG-STSGGCVLKKTCGQSLQFCAELLGLDEEDLRVSLTSRVMLTTAGGTKGTVIKVPLKVEQASSARDALAKAIYSRLFDHVVTRINQCFPFDSSAHFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLVESKVVGILDILDEENRLPQPSDQHFTETVHSKHKDHFRLTVPRKSKLQVHRNVRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLACLVSESKDKFIGELFEN-SNHSKDTKQKAGKLSFISVGNKFKTQLNILLEKLHSTGSSFVRCVKPNLKMVGHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRAPFHELYNMYKQYMPAKLTRLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNKWLICSRWKKVQWCALSVIKLKNKMLYRAQACVQMQKTVRMWLCRRKHKPRIDGLVKAQNLKKRMEKLNEVVSGLKEGKQEMSKHMQDLDSSIDAHIRKIKS-IVMSRMDIDHEHQALVTRSQELLSAMQ---KKKQEEEEMERLKRIQEEMEKERKRREEEEQKRKREEEERRQKAEMELKRKQEEEERKKREEEERKLQEEMELQLEAEREQETSRQAVLEQERRDRELALRIAQSEAELIPEETPPDAGLRSVAPPQ-------KLKSLTMEEMAKEMSDLLARGPQVSANNAQADVKKYELSKWKYAELRDAINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNVQEE-QRAPKAITDYVGIIGSQAFIAQQNPVVPAAVPRQHEIVMNRQQRFFRIPFIRPGDQYKDPQSKKKGWWYAHFDGPWIARQMELHPDKHPILLVAGKDDMEMCELSLEETGLTRKRGAEILPRQFEEIWERCGGIQYLRNAIESRQARPTYATAMLQSMLK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01989-1", "uniprot_id": "MYS9_DROME", "id": "Q01989-1", "name": "Myosin heavy chain 95F", "aln": "MLEDTQLVWVRDAAEGYIQGRITEIGAKEFEVTPTDRKYPKRTCHFDDIHSSCDGP-QDHDDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGPIETKILDANPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLRDKLSLGKPDDYRYLS-GCTQYFANAKTEQLIPGSQKSKN---HQQKGPLKDPIIDDYQHFHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPFQASNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQDIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPS-----GSSTSVRGKLNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSMYKSVLPPELVSLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLAIVAKVKKWLIRSRWVKSALGALCVIKLRNRIIYRNKCVLIAQRIARGFLARKQHRPRYQGIGKINKIRTNTLKTIEIASGLKMGREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLNTKLKEQQQAEEQERLRKIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEEDRRAALALQEQLEKEAKDDAKYRQQLEQERRDHELALRLANESNGQVEDSPPVIRNGVNDASPMG--------------------PNKLIRSENVRAQQQALGKQKYDLSKWKYSELRDAINTSCDIELLEACRQEFHRRLKVYHAWKAKNRKRTTMDENERAPRSVMEAA----------FKQPPLVQPI---QEIVT-AQHRYFRIPFMRAN----APDNTKRGLWYAHFDGQWIARQMELHADKPPILLVAGTDDMQMCELSLEETGLTRKRGAEILEHEFNREWERNGGKAYKN----LGAAKPNGPAAAMQKQQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* : **. ..::*: * * :*... : : * .:: . . ..::..: :. :. :***.** *****:*.*:: ** ** ***:*********** :* ::*:.::**.*:*:*** ****:****** ***:* *:****************.**::*:** *:.:. *: :*::***:*********.***********:*:*:: * ****::*********** *. ******:** * ***.:::*: : *..** :*** ***::*:. .::: * . ** : : *.:***::** .* .: *: ::**.* ***.:: :**.******* *** .. *** :.: . :* : ***:*: :**.:*.:*** :..** ***** ****: :*..*******::**:***::* :**.:**::* :*** ******** ****************:***:.***:*****::***.* *: :.**** *:*:* * *:: :****.:**:** .**: **.. :*:** :**.*:* **.:**:***::*********:* **:******** ** *: *. : :: ** . .:.. ***.*****.******. *::**...*:.*:**:*** ** .::***: *:**:*** :***:**: *:***. * :**.***. :* :*. * .* **:*:*::*.*. *:***:*:********.***:**:***::: :* :*: ** *** * :*.****:*:: ** .. : *: * :*.:::*:** :*: * .::.. : * .. ** *: *: :::: . * : *** ::: ::: : :: :.* :: *::*: ** ***::*** :* ** :* :*: ::.* *::* * *** :** * :* ::*:::: :: ** : ::::. : * ** **:***:*:*:.. : :.. . * * : . :*::******:****:********** ***:*************:**:**.. * ***::: : ::* . :** *:*:*****:*. *:..*:* ******* *********.** *******.***:****.*************** ::*:. *** ** * . *:*. .:* :*. ", "identical_positions": 601, "similar_positions": 365, "identity": "46.02%" }, { "cls_id": "homologset.agr.FB:FBgn0011227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYX1-1", "uniprot_id": "B2RYX1_RAT", "id": "B2RYX1-1", "name": "Complex III subunit 9", "aln": "MASPTVTSRLYSLLFRRTSTFALTIAVSALFFERAFDQGADAVYDYINEGKLWKHIKHKYEKQE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZK76-1", "uniprot_id": "A0A8I5ZK76_RAT", "id": "A0A8I5ZK76-1", "name": "Complex III subunit 9", "aln": "MASPTVASRLYSLLFHRTSTFALTIAVSSLFFERAFDQGADAIYDHSKEGKLWKHIKHKYENQE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1I1-1", "uniprot_id": "QCR9_MOUSE", "id": "Q8R1I1-1", "name": "Cytochrome b-c1 complex subunit 9", "aln": "MSSPTIPSRLYSLLFRRTSTFALTIAVGALFFERAFDQGADAIYEHINEGKLWKHIKHKYENKE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDW1-1", "uniprot_id": "QCR9_HUMAN", "id": "Q9UDW1-1", "name": "Cytochrome b-c1 complex subunit 9", "aln": "MAAATLTSKLYSLLFRRTSTFALTIIVGVMFFERAFDQGADAIYDHINEGKLWKHIKHKYENK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XY35-1", "uniprot_id": "QCR9_DROME", "id": "Q9XY35-1", "name": "Cytochrome b-c1 complex subunit 9", "aln": "------MKVIYNTLFKRTSTYAVAIIASAFFFERALDVTSVAIFEGINKGKLWKDIKGKYE---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22289-1", "uniprot_id": "QCR9_YEAST", "id": "P22289-1", "name": "Cytochrome b-c1 complex subunit 9, mitochondrial", "aln": "----MSFSSLYKTFFKRNAVFVGTIFAGAFVFQTVFDTAITSWYENHNKGKLWKDVKARIAAGDGDDDDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*. :*:*.:.:. :* .. :.*: .:* : :: ::*****.:* : ", "identical_positions": 12, "similar_positions": 26, "identity": "17.14%" }, { "cls_id": "homologset.agr.FB:FBgn0011230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TL32-1", "uniprot_id": "UBR4_RAT", "id": "Q2TL32-1", "name": "E3 ubiquitin-protein ligase UBR4", "aln": "-MATSGGEEAAAAAPAPGAPATGQDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTG--CSRLDRTEIITFTAMM---KSAKLPQTVKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRTVPSPPISPQALVEGENDEQSSTEQASAVKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVVANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAILHVG--SAQQVRTGSTSS--------------KEEDYESDAATIVQKCLEIYDMIGQAISSSRRAGGEHFQNFQLLGAWCLLNSLFLILHLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAIKLLTSLFQDLQVEALH------KGWETDGP--PAVLSIMAQSTSTQRVQRLIDSVPLTNLLLTLLSTSYRKACVLQRQ-RKGSMSSDASASTDSNTYYEDDFSSTEEDSSQ--------------------------------------------------------DDDSEPILGQWFEETISPSKEKAAPPPPPPPPPLESSPRVKSPSKQASGEKGNILASRKDPELFLGLASNILNFITSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGSSDE---------------------------DFAAALYHFNHSLVTSDLQSPNLQNTLLQQLGVAPLSSGP--WPLYIHPQGLSVLSRLLLIWQHKAGAQGDPDVPECLKVWDRFLTTMKQSALQG--VVPSETEDLNIEHLQLLLLIFHSFSEKGRRAILTTLVQSIQELSVNMEVQMRSAP------LILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDSSSSSRRANIPLYHGFKEVEENWSKHFSS--DAAPQPRFYCVLSTEASE---EDLNRLDSEACEVLFS--KLVKYDELYSSLTALLAAGSQLDTVKRKENKNMTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVSWIKDHLIRQGMRPEHAGSLVELAAS----KCSSVKYDVEIVEEYFARQISSFCSIDCTTVLQLHEIPSLQSIYTLD-------------------AAVSKVQVSLDEHFSKMAAETDPHKSSEITKNLLPATLQLIDTYASFTRAYLLQNLNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQSVCESWNN-INTNEFPNIGSWRN-AFANDTIPSESYISAVQAAHLGTLC-GQSLPLAASLKHALLSLVRLTGDLIVWS--DEMNPAQVIRALLPLLLESSTESAAEISSNSLERILGPAESDEFLARVYEKLITGCYNILANHAD----PSSG--------------LDESVLEECLQYLEKQLESSQARKAMEEFFSD--GGELVQIMMATANEDLSAKFCNRVLKFFTKLFQLTEKSP-NPSLLHLCGSLAQLACVEPVRLQAWLTRMTTSP---------------------------------------------PKDSDQLEVIQ-----------------------------------------------------ENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLTPMATDMLANGDGTGFPELMVVMATLASAGQGAGHLQLHNAAVDWLGRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLA---------------LVKRTPSSGMSSTMKES-AFQSEPRVSESLVRHASTS-PADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQAN-FSFAPLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQALSELHTVDKVVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYMYTQLMEEASSAQQGPFYVTNVLEINHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYSQGKSFAATVSRSTLEVLQLFPINIKSSNGGSKTSP--ALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPS--------------SVISIMKPVRKRKTATITARTSS----------QVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTMEISNNSSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADRKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEDFPSASVSSVCPPNLNQSNSTGDSDSAAPATTSGTVLE-----------RLVVSSLEALESCFAVGPIIEKERNKHAAQELATLLLSLPAPASVQQQSKSLLASLHSSRSAYHSHKDQALLSKAVQCLNTSS------KEGKDLDPEVFQRLVITARSIAVTRPNNLVHFTESKLPQMETEGAEEGKEPQKQVEGDGCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPDGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASGVCACNSSVTLSAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGEAEGDVHTSN---RLHMVRLMLLERLLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLAQLIAELGMDKKDVSKKNE-RSALNEVHLVVMRLLSVFMSRTKS------GSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWK-------------GQQSEEEPVTTS----QLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTSSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSVLYFLLQVS-FLVDEGVSPVLLQLLSCALCGSKVLAALAASTGSSSVASS-APPAASSGQTTTQSKSSTKKSKKEKKEKEKEGESSGSQED-QLCTALVNQLNRFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYRNSNKAQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTAQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQEDSGTAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAIREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNEIHAQAQLWLKRDPKASYEAWKKCLPIR-------------GVDGNGKSPSKS--ELHRLYLTEKYVWRWKQFLSRRGKRTTPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALASVPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLIASCHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVLQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTN-EGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYRMAGVMAQCGGLQCMLNRLAGVKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKN----LDADIWKKFLSRPALPFILRLLRGLAMQHPATQVLIGTDSITSLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQGFLEQP-REKWTESAFDVDGPHYFTILALHVLPPEQWKATRVEILRRLLVASHARAVAPGGATR----LTDKAVKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFLDAAGLLSEITDPESFLKDLLNSVP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AN08-1", "uniprot_id": "UBR4_MOUSE", "id": "A2AN08-1", "name": "E3 ubiquitin-protein ligase UBR4", "aln": "-MATSGGEEAAAAAPAPGAPATGQDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTG--CSRLDRTEIITFTAMM---KSAKLPQTVKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRTVPSPPISPQALVEGENDEQSSPDQVSAAKTKSVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVVANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAILHVG--SAQQVRTGSTSS--------------KEDDYESDAATIVQKCLEIYDMIGQAISSSRRAGGEHFQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAIKLLASLFQDLQVEALH------KGWETDGP--PAVLSIMAQSTSTQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQ-RKGSMSSDASASTDSNTYYEDDFSSTEEDSSQ--------------------------------------------------------DDDSEPILGQWFEETISPSKEKAAPPPPPPPPPLESSPRVKSPNKQASGEKGNILASRKDPELFSGLASNILNFITTSMLNSRNSFIRSYLSASLSEHHMATLASIIKEVDKDGLKGSSDE---------------------------DFAAALYHFNHSLVTSDLQSPNLQNTLLQQLGVAPFSEGP--WPLYIHPQGLSVLSRLLLIWQHKAGAQGDPDVPECLKVWDRFLTTMKQNALQG--VVPSETEDLNVEHLQLLLLIFHSFSEKGRRAILTMLVQSIQELSVNMEVQMRTAP------LILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDSSS--RRANTPLYHGFKEVEENWSKHFSS--DAAPQPRFYCVLSTEASE---EDLNRLDSEACEVLFS--KPVKYDELYSSLTTLLAAGSQLDTTRRKEKKNVTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVSWIKDHLIKQGMKPEHAGSLIELAAS----KCSSVKYDVEIVEEYFARQISSFCSIDCTAVLQLHEIPSLQSIYTLD-------------------AAVSKVQVSLDEHFSKMAAETDPHKSSEITKNLLPATLQLIDTYASFTRAYLLQNLNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQSVCESWNN-INTNEFPNIGSWRN-AFANDTIPSESYISAVQAAHLGTLC-GQSLPLAASLKHTLLSLVRLTGDLIVWS--DEMNPAQVIRTLLPLLLESSTESAAEISSNSLERILGPAESDEFLARVYEKLITGCYNILANHAD----PNSG--------------LDESILEECLQYLEKQLESSQARKAMEEFFSD--GGELVQIMMATANEDLSAKFCNRVLKFFTKLFQLTEKSP-NPSLLHLCGSLAQLACVEPVRLQAWLTRMTTSP---------------------------------------------PKDSDQLEVIQ-----------------------------------------------------ENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLTPMATDMLANGDGTGFPELMVVMATLASAGQGAGHLQLHNAAVDWLGRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLA---------------LVKRTPSSGMSSTMKES-AFQSEPRVSESLVRHASTS-PADKAKVTISDGKVTDEEKPKKSSLCRTVEGCREELQNQAN-FSFAPLVLDMLSFLMDAIQTNFQQASAVGSSSRAQQALSELHTVDKGVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSIDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYMYTQLMEEASSAQQGPFYVTNVLEINHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYSQGRSFAATVSRSTLEVLQLFPINIKSSNGGSKTSP--ALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPGTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPS--------------SVISIMKPVRKRKTATITARTSS----------QVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNSSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADRKLSLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEDFPSASVSNICPPNLNQSNGTGESDSAAPATTSGTVLE-----------RLVVSSLEALESCFAVGPIIEKERNKHAAQELATLLLSLPAPASVQQQSKSLLASLHSSRSAYHSHKDQALLSKAVQCLNTSS------KEGKDLDPEVFQRLVITARSIAVTRPNNLVHFTESKLPQMETEGADEGKEPQKQ-EGDGCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPDGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTAS------------APASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTATGHQEGDGSEGEGEGEAEGDVHTSN---RLHMVRLMLLERLLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLAQLIAELGMDKKDVSKKNE-RSALNEVHLVVMRLLSVFMSRTKS------GSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWK-------------SQQSDEEPVAAS----QLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTSSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSVLYFLLQVS-FLVDEGVSPVLLQLLSCALCGSKVLAALAASTGSSSVASSSAPPAASSGQATTQSKSSTKKSKKEEKEKEKEGESSGSQED-QLCTALVNQLNRFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYRNSNKAQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTAQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQEDSGTAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAIREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNEIHAQAQLWLKRDPKASYEAWKKCLPIR-------------GVDGNGKSPSKS--ELHRLYLTEKYVWRWKQFLSRRGKRTTPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATVPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLIASCHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVLQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCATN-EGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYRMAGVMAQCGGLQCMLNRLAGVKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLETNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFEKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKN----LDADIWKKFLSRPALPFILRLLRGLAMQHPATQVLIGTDSITSLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQGFLEQP-KEKWTESAFDVDGPHYFTILALHVLPPEQWKAIRVEILRRLLVASHARAVAPGGATR----LTDKAVKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFLDAAGLLSEITDPESFLKDLLNSVP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T4S7-1", "uniprot_id": "UBR4_HUMAN", "id": "Q5T4S7-1", "name": "E3 ubiquitin-protein ligase UBR4", "aln": "-MATSGGEEAAAAAPAPGTPATGADTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTG--CSRLDRTEIITFTAMM---KSAKLPQTVKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRTVASQPISTQTLVEGENDEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAILHVG--SAQQVRTGSTSS--------------KEDDYESDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAIKLLTSLFQDLQVEALH------KGWETDGP--PAALSIMAQSTSIQRIQRLIDSVPLMNLLLTLLSTSYRKACVLQRQ-RKGSMSSDASASTDSNTYYEDDFSSTEEDSSQ--------------------------------------------------------DDDSEPILGQWFEETISPSKEKAAPPPPPPPPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITSSMLNSRNNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGSSDE---------------------------EFAAALYHFNHSLVTSDLQSPNLQNTLLQQLGVAPFSEGP--WPLYIHPQSLSVLSRLLLIWQHKASAQGDPDVPECLKVWDRFLSTMKQNALQG--VVPSETEDLNVEHLQMLLLIFHNFTETGRRAILSLFVQIIQELSVNMDAQMRFVP------LILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDSNS--RRATTPLYHGFKEVEENWSKHFSS--DAVPHPRFYCVLSPEASE---DDLNRLDSVACDVLFS--KLVKYDELYAALTALLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYINQLSMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHASSLLELASTT---KCSSVKYDVEIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLD-------------------AAISKVQVSLDEHFSKMAAETDPHKSSEITKNLLPATLQLIDTYASFTRAYLLQNFNEEGTTEKPSKEKLQGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNN-INTNEFPNIGSWRN-AFANDTIPSESYISAVQAAHLGTLC-SQSLPLAASLKHTLLSLVRLTGDLIVWS--DEMNPPQVIRTLLPLLLESSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILANHAD----PNSG--------------LDESILEECLQYLEKQLESSQARKAMEEFFSD--SGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSP-NPSLLHLCGSLAQLACVEPVRLQAWLTRMTTSP---------------------------------------------PKDSDQLDVIQ-----------------------------------------------------ENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLTPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMILECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLA---------------LVKRTPSSGMSSTMKES-AFQSEPRISESLVRHASTSSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQAN-FSFAPLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQALSELHTVEKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLCVDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEINHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRTTLEVLQLFPINIKSSNGGSKTSP--ALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPS--------------SVISIMKPVRKRKTATITTRTSS----------QVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPSASVSNICPSNLNQSNGTGDSDSAAPTTTSGTVLE-----------RLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSS------KEGKDLDPEVFQRLVITARSIAIMRPNNLVHFTESKLPQMETEGMDEGKEPQKQLEGDCCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTAS------------APASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGETEGDVHTSN---RLHMVRLMLLERLLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSKKNE-RSALNEVHLVVMRLLSVFMSRTKS------GSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWK-------------SQQNDEEPVATS----QLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKITDTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSVLYFLLQVS-FLVDEGVSPVLLQLLSCALCGSKVLAALAASSGSSSASSSSAPVAASSGQATTQSKSSTKKSKKEEKEKEKDGETSGSQED-QLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGTAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNEIHAQAQLWLKRDPKASYDAWKKCLPIR-------------GIDGNGKAPSKS--ELRHLYLTEKYVWRWKQFLSRRGKRTSPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTN-EGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIRDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCNFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKN----LDADIWKKFLSRPALPFILRLLRGLAIQHPGTQVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQGFLEQP-KEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATR----LTDKAVKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFLDVAGLLSEITDPESFLKDLLNSVP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IL79-1", "uniprot_id": "A0AC58IL79_DANRE", "id": "A0AC58IL79-1", "name": "", "aln": "-MASSGG-----------------DGEPEWTAAVRPLLSASYTAFETKELPQLIGSIINSESEILHHDKQYEPFYSSFVALSAHYITTVCGQIPRNQLLSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTG--CSRLDRTEIITFTAMM---KSAKLPQTVKTLSDVEDQKELPSPVNPELRHKEVQMNFFNQLTSVFNPDISVLASPSAHMQSENECDEQTTTDQATQAKMKNAFISQNVSSLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLTPGRLLDVTVLALSCLYAGVSVATCMAILQVG--SGLQLRSASTGS--------------KEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLYLILNLSPTALADKGKEKDPLAALRVRDIATRTKDGAGSPKLGPGKGHQGFGVLSVILANHSIKLLTSLFQDLQVEALHRLCCVIQGWASDGP--PAELNIMAQSTSIQRVQRLIDSVPLTNLLFTLLSTSYKKACVLQRQ-RKGSVSSDASASTDSNTYYEDDFSSTEEDSSQAEYRVCLWFTELVSGLRSLRDFFRSFLSTARFSRRTAVRPESAERRQERTKAACFSDDDSEPILGLWFEETISPSKEKVAPPPPPPPPPLETSPRLKSPSKLNTVENGNILASRKDPELFLSLASSILNFITTSMLKSRNNFIRNYLSVSLTEQHMATLASIIKDVDKD-VKGSSDD---------------------------EFASALYHFNHSLVTSDLPSPSLQNTLLQQLGVAPFSEGP--WPMYIHPQSLSVLSRLLLIWQHKASQQGEPDVPECMKVWERFVGTLKQHTLQG--AVPAD-EDLNVEHLQLLLLIFHNFSEKGRRTVLTLCMQAIAEIASNADSQLQAVP------LNLARILLVFDYLLHQYSKAPVYLFEQVQYNLLTPLASSASAGQDGGK---RGAVPLYYGFKEVEENWAKHCSAGRNSTVQPKFYCVLSPEASE---DDRSRLDGKVFQVLFN--GAVKYDDMYSSLISLLAAGSRFDTARRQENKPITPVEACSLQYYFLVLWKILGVLPPSKAYIEQLKSGNSDPSESDILHTLRWSSRLRVSTYVNWIKEHLVKQGMKADLATSLIEVAST----KCSAVKYDVELAEEYIARQISSFCCVDPNSILPLHQVPSLQTIYTLD-------------------AVISKVQVSLDEHFSKIAADTDPNKSSEITKNLLPATLQLIDVYTAFTRSYLLMSLPEEGEN-KPTEAKLQGYAAVLSIGSTRCKANLLGQTVMQNLPSAVQTLCETWNN-IHTNEFPNIGSWRN-AFANDTIPSESYISAIQAAHLGTLS-NQSLPLASSLKHILLSLVRLTGDLIVT---EELNSPQVIRTLLPLLLESSTESVAEICSTSLERILGPAESDAFLALVYERLITGCYNIIANHSD----PNSG--------------LDETILEECLQYLEKQLESSQVRKAMEEFFSF--SGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSP-NPSLLCLCGSLAQLACVEPSRLQAWLRRMTASP---------------------------------------------PKDSDQLDTVQ-----------------------------------------------------ENRQLLQLLTSYIVRDNSQVGEGVCTVLLSTLIPMATEMLASGDGAGFPELMVIMATLASAGQGAGHLQLHRAAIDWLTRCKKYLYQKNVVEKVTANVSQGKHASMLECACHIISYLADVMNALRQSSGQGSSQLLMDGEEKAIEVDSDWVEELAVEEDDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCQVRPNTSGHHGKRATAALVKRSPSSGMSSTMKESSAFQSELRMPESAIRHQSSS-PADKGKVTICDGKNSDDDKPKKSSVCKNIEGCREDLLIQVASSSTAALVLELLIFLMDAIQTNFQQASAVGSSSRAQHALNELHTQDKTVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCNEDYLAVCGLKDCHVLTFSSTGSVSDHLVLHPQLATGNFIIKAIWLPGSQTELAIITADFVKIYDLSVDALSPMYYFLLPSSKIRDATFLFNEEGKNIIVIMSSAGYMYTQVMDESSSAQHGPFYVTNVLEINHEDLKDSNGQVAGGGVSVYYSHVLQMLFFSYSQGKSFAATVSRSNMETQRLFTINVKGSNGGSKTSP--ALCQWSEVMNHPGLVCCVQQTTGIPLVIMLKPDTFLIQEIKTLPAKAKIQDMVAIRHTASNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPS--------------SVISIMKPVRKRKTATATTRTSS----------QVTFPVDFFEHNQQLTEVEFGGNDLLQVYNGQQIKHRLNSTGMYVANTKPGGFTVEVVNNNNSMVMTGMRVQVGTQAIERAPSYIEIFGRTMQLNLTRSRWFDFPFTREEALQADKKLSIFIGASVDPAGVTMLDSIKIYGKTKEQFGWPDEPPEDFPSAAVNNVCSPNLNQGNGTGESDVTSPITTSGTVLESCETESLSALDRLVVSSLEALESCFAVGSLNEKEKNKVAALELATLLLSIPTPAGVQQQTKGLLASLHTSRTAYHNHKDQSLLSNAVQSLNACS------KEGKELDPDVFQRLVITARSIAIMRPNNLVHFTESRLPQSDTDVGDDG---LKQADTESCSFIMQLVTNFWKLHALKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDYINVASKIYMQMLLCPDTSVSFACKQALIRVLRPRNKRRHVTLPSPPRSNTPMGDKDDDDDDDADDKMQPSNMTGGEGGRQESQEQNEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTAS------ALVMLSAPASDDEGSTAATDGSTLRTSPAEHGGSVGSESGGSAIDSVAGEHNVSGRSSAYGDTTVEGHPAGPGSVSSSTGAISTTTAQHEGEGSEGEG--ETEGDIHTSN---RLHMVRLMLLERLLQHLSQLHTVGGVQAIPYMQVILMLTTDLDGEDEKDKGALDDLLAQLIAELGMHKKDVSKKNE-RSSINEVHLVIMRLLSVFMSRTKS------GSKS-SSESSSLISNATATALLSMGAIDYCLHVLKSLLEFWK-------------TQQGEEEPTATS----QLLKPHTSSSPPDMSPFFLRQYVKGHAADVFEAYSQLLTEMVLRLPYQIKKIADANPRIPPPIFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRGGIVTATSGSALQYDTLISLMEHLKACAEIATQRTINWQKFCMKDDSVLYFLLQVS-FLVDEGVSPVLLQLLSCALCGSKVMAASSGSSGGGSGTSQ-----------PSQSKSSSKKSKKEDKEKDKEGDGAGSQED-QLCTALVSQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYRNSNKSQQELLLDLMWAIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRAQNHILTNHPNSNIYNTLSRLVEFDGFYLESDPCLVCNNPEVPFSNIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFSDFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLESLLSKVNEAAPEKPQDDTGAGAGLGTSTASVNRYIQQLAQEYSGDCKTSFDELSKIIQKVLASRKELLEYDLHQREAATKSSRTSAQQTFTASQYRALSVLGCGHTSSTKCYGCASAVTGHCITLLRALATNPAIRQILVLQGLIRELFEYNLRRGTGAMREEVRQLVCLLTRDHPEATQQMNDLIIAKVSAALKGHWANPDLVSSLQYEMLLLTDSIAKEGGCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDAAVESLTTVKPYNNEIHAQAQLWLKKEPKASYEAWKKCLPAR-------------CQETVSKPSNKA--EIRRQYLMEKYVWKWKQFMRSRSEGLFPRLLKLGHNNWLRQVLFTPATQAARQAACTIVEALTTIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARGVLPYIGNLITKEIAHLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLSVAEVYKKVWCPTN-EGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDDEEVYKMAGVMAQCGGLECMLNRLSGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGASIAEQVLSIMEIILDEANAETVSEDKGNLLLTGDKDQLVMLLDQINTLFVRSNPSVLQGLLRIIPYLSFGELEKMHILVERFKPCCNFDKYDEEHSADDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKQIPCAKN----LDADVWKKFLARPALPFILRLLRGLATQHPPTQMLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHADVNLKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTSLLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVSLEEFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDTKLLFLRFAMEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFLEQP-CEKWMETSYEVDGPHYFTILAMHILPPERWRTTRVDILRRLLVTAHARKVSPGGANK----LTDKAVKEYAVYRSPLLFWGLVDLIYDMFRKVPTSNTEGGWSFSLAEYIRHNDMPIYEASERVLRAFQDELMPAESFSEFLDVVGLLSDIPDPDAFLQDLLNSVP------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT5-1", "uniprot_id": "POE_DROME", "id": "Q9VLT5-1", "name": "Protein purity of essence", "aln": "MSAHSGG--------------------TDWNSVVKALILNRTGALNKNEVVNLLKAITRCEHDFFEEESNFTQFYTAFAALAADKLMQIK-TICQTQICQLHDATAVLIRFIIYRLPR---VSVYETKWLLGALKMLCEGRECPASASSSMFDYNAVANVLKSCKHPESTTKSIMPSSSSSGSGASNDKESPKSEIKRSRSDLSSVILQQLIAPLEPGKMTWVPLSEEVTDCTEQI---------LAANVEYFQEQNGVDTLLDVCVSLPILNRYRSKYMETINGGKSLYLPLTQVEATAVKSSMNHMLTDLTILSQAQALIEMQPLTPSRIERLSMCGIAALYNAVLTSIATSVLGMSQASSSQKQTASTSQGSGVGGSSGGQSNKDHDDFEDQACSIVNKALEIYSNIGHMFKTSARIH--VYQNHLCYGSWLLISGIQGAMGASGSGGSSSDSASKSASKATKSGSEAGTAPTTPIARVNLFKVQQGFGELNAAIANHSIKLLSELIEDLKVEAACG-----QSLESTELPEPAQFDILQNYSSLERIVRVLNTATLHQLFTFLATVAYRKACTLKRASAKDRTECEPISYSDSTTYFNDSLSCSDNSE----------------------------------------------------------EDDSESYLGHWFKETLSPETHDDN---------------ANTSTQERAEQKSALVPKLDEPHEYLDLAADIFCFLDQFLAN-RHAYMQRYVKAGVSDQQMLLMANIIKDFDRDVMRNESDQGSGNAPAASAGAGTSAGASTKWQTSMIRFSGAAGRYIHNLISTSLLSEQLQSNLLQHLSISPWSTDTNTWPLQVYPSTLSVLVQILLLKPTQEKE------AACLSVWHRLINTLVEGVCSSNTASDSDYEDLNIEHAQLLLFLFHSLNLMQKKSILLLTAGGVIRCAEVCRGISEDRPVKNSQIMLLSRLLLFLEYLMKHLYNAPPELLDQVRWNLFS--VSSMPDTQKITDLLNCRTKLNSYCRHDIEENFRKSAGEY-GSSIRPTFYSLVMGDPEISYWAQEFKLDGLAWNFILCTPDKLKYPLLVDALTDILSI-TDMSMYSKEKDKEASMHNLCAIQYCFTIAWKLNLGLPPSTSHVESLKAERSPN-----LHSLMWSIRLPLASSHYLVVSSLIKQGMYTQYAETLWTHVGDIGADIKYSLKQTILGVEAFNSQMNGNGTPRLSDLILFDSLVAHMQAVAWANKEGLKWPRKESEDAAGEQSAGTSLTSSSNDPELYSSNESIDDQKLKQDDDGKLSSDLQKYNQLVNELMVKLMNSYQLLSVIVRGQMLKQLSSSTPEKALNLIVPIVSDKPAIMLELHAAFLKLLPNEDKQLIANEWPKCLMVNDFAFNGKQHPVEPYILNVIDAHIIELTRGSNYSTLHTLKHCLKSILQLFELLLPHRTANAEVETQLKQLLISSMLDMRTDYLQGHSEHCLREILSGLTQEAQKLLLYEHMVGYCYRMLKEFAADLRQPQSAGPSGGAPLDQDRAMFNESMLFAVLKTMFKMLEKPVAVQAMRQFFKDQRSGSLTTLLLSFTGTSLPVSYARKMLQFVNRLFQLSLQADSQFQHEDLVECFSELATVDVARLKQWLGHIIYGPNVSTDVSTSEALDTTCRMLTSILQPSSSSSSNAQTPTNMATVSAMPSISDQLDPMEIEYDCGTAAGGGESNPGTGGAAANTSQILSLWQAAQPNPSEESSQACDHSDSERNGALLLSFVKSLVKDQSKASQIAPPLFQALLQLGQTLISPPQEGCDFADVLQIMITLADASPARGHVALFNTTLLWLELAKLQLP--------------DKHLKHAENVSAQLRYLSELLQSIGFRGSR--QHNPPWDDELQTDIDELYDELAEEGEQDSLLDDSDEDTLNNKLCTFSQTQKEFMNQHWYHCHTCNMINTVGVCSVCARVCHKGHDVSYAKYGNFFCDCGAKEDGSCQA---------------LSRRIGSNEVRDSAGIG---SYLPSHMSLLAGKKRSSLPVGQPVLTRKDSLTN----ERIAVLTKLLEPYRETLQHQDQWLLVVRCILEYFDLLLPSINENCMLYSIVGCHKRATAALERLHLLEQSFQVTDQLMFATLGSQEGAFENVRMNYSGDQGQTIKHLLSSGVVRRVAFCCLSSPHGRRQQLAVSHEKGKVTILQLSALLKQADASKRKLTLTQLSSAPIACTVISLAANPCNEDCLAVCGLKECHILTFSSSGSTNEHIVVNPQLENGNYIKKAVWLPGSQTLLAVVTSDYVKIYDLAVDTYSPKYYYLVAVGKIRDCTFVYQD-GNYNMLTFASSGYIYTQQLDQQSLAVHGDFYVTNTLELSHQHIKDIAGHIGGGGVSIYYSHTLQLLFYSYSCGRSFFSPLTNVSEGVKGIYHLDTNSASKSASKGPLQPLVQWTEVTGHPGLVYASMQTSNNPIILMITPERIYLQEIKAQSAKSRIMDVVGIRHAVAG-VEKTTLLLLCEDGSLRIFSAQPEYTSFWLSPQVQPFGNQLYSSTLMAKGGGSGSTSKSKSNTASGKMTSRKASQQQKQPTAGGQPVFPIDFFEHCNMLADVEFGGNDLLQIYNKQKLKTRLFSTGMFVASTRSNGFTLEVINNDPNVVIVGIRVLIGTQDVQRAPQSVTILGRTIPTPVRRARWFDIPLTREEMLQSDKLLKVVFAKAPDPEHVTLLDCIEVYGKSKELVGWPDESEDVTVPGSSAPAVSSSQASSANFGEG------FNCITQLD-----------RMANHLLEVMDCALHLLGSGVPASMRQKAVKTASALLLLPTPNPVQTQARYVLATLYGTRALYHNYKDGVLLQFVNRELQSMQPKLEKLETLREIDPEAFYRLVLMVRGIANARPQSLAKICVENN----------------------YDIVPTLMGIVLELHKVTPTLDEPVNIVKRGLCQPETIVHCLVEIMYGFALADPGQVGRMTKYFIDLLKHDASVISHSAKEALILLLSPRMKRRKVAIVTPPACSTPTPSTSTMQALQAAASSAASDIIEEAAGVVVDGSVGGGGLPEPNADAEGAAVGVGG-VGQQQMLNLEAFMGG--GFPRLLGLPEDADDEAIMDIAIALSLQQHGGDANALQSLQQGLANLQGIRQATAMAAAVNAAANVS-----------LGGSDDDEGSNVATDGSTLRTSPAEPAGSGGSESGGSGVESIG---GTSARSSNFGDHANASPPRQGSTKDDQEQPGPSGVAGSGGVAVLSAMSSSEDNEANEDDKLSKLHDLRIAVLESIIQHLGTFDLCNGLQAIPLIQVILMLTTDLNGNNERDQQVLHDLLTALVDYVEIGKRGAAARMETKCPGNEVRLALLSLFGVLMGKTKSKQTGTTSPPHQFKDNSSFVASTTANVLSKSGAFVYALEALNTLLVHWKNVLGDPYAAGGGLASQSAQASGGASGPGVQLLKPIKHGPKPDISILIPHNYLK-NYPDIFESYDGLLTEIIVRLPYQILRLSSAHPDNYDSGFCEAMTFTLCEYMMLNLNTLLRRQVRKLLMYICGSKEKFRMYRDGHSLDAHFRVVKRVCN--IVSSKTGAPYNANPPMLSYDALVELTEHLRTCQEISQMRTGNWQKFCVVHEDALAMLMEIACYQLDDGVSPIIIQLLQAAVCN------LPPPSGSKQAQPQ-------------PSTSSASGKLRTDREKSEDTDAYYSKFDPAQCGTFVHQIFRYACDALIIRFVRIFLLENNITQLRWQAHSFMTGLFEHANERQREKLLNIFWNLWPLVPTYGRRTAQFVDLLGYLTLSTRSITERLPEFVSRAVDVLRQQNELLCKHPNAPIYTTLESILQVNGYYLESEPCLVCNNPEVPMANIKLPSVKSDSKYTTTTMIYKLVQCHTISKLIVRIADLKRTKMVRTINVYYNNRSVQAVVELKNRPALWHKARSVSLQSAQTELKIDFPLPITACNLMIEFADFFETVSGSSENLQCPRCSAAVPAYPGVCGNCGENVFQCHKCRAINYDEKDPFLCHSCGFCKYAKFDFSMYARVCCAVDPIESAEDRVKTVSLIHSSLERADRNYRQLLTNKQMLELLIQKVAEHRSSDRMVEDNMAS--VHSTSQVNKIIQLLAQKYCVESRTSFEELSKIVQKVKACRSELVAYDRQQQDQPPVNPG---------------STTGAENPTTNRCYGCALASTEQCLTLLRAMAYNYDCRVCLYSQGLVSELAEHNLRRGTPLIQEEVRNLLVVLTKDNAEACMHLLQLVTTRVKNALMGSIPLISLEAAVHQEMTLLEVLLGQDDICWEYKLKVIFELFISNCRLPR-GPVTAVLHPCLRIMQNLICPVLPGSKPNQKVATTDLCSMKMFEGNT-VDYRAWLNSDRNHEYAAWSKRMPSNNQAKLKNAKDQNVAASGGSDAPPKSRREVRVAFLSEKYGKRWRERVLDKQRVIKPLVFNA---KWIQPLLFNANSRFGRQLACSLLSSLSRTNERRQQALNMLTSFLKHVGEAGEASAEYLMLYKNMATEQPWLQYLVLKGVLSQISQLLAIEISKVHRMEEYSLSSDLSLGYALRQYVELLWLLLECPNIRRTYKTRMLGPVLESYLALRSLVVQRTRLIDDAQEKLLEMLEDMTSGTEEETRAFMEILIDTVEKTRMNDIKTPVFVFERLYSIIHPEEHDESEFYMTLEKDPQQEDFLQGRMLGNPYPSSEMGLGPLMRDVKNKICTDCELIALLEDDNGMELLVNNKIISLDLPVKDVYKKVWLAEGGDRDAMRIVYRMRGLLGDATEEFVETLNNKSQEQVDTEQLYRMANVLADCNGLRVMLERIGSLQRISRNRELIQVLLKLFLICVKVRRCQEVLCQPEIGAINTLLKVLQMCLQSENDSIQS---AVTEQLLEIMETILSKAASDTLDSFLQFSLTFGGPEYVSALISCTDCPNVRNNPSVLRHLIRVLAALVYGNEVKMALLCEHFKDTLNFNRFDNERTPEEEFKLELFCVLTNQIEHNCIGGTLKDYIVSLGIVERSLAYITEHAPCVKPTLLRTDSDELKEFISRPSLKYILRFLTGLSNHHEATQVAISKDIIPIIHRLEQVSSDEHVGSLAENLLEALSTDSATAARVQQVRDFTRAEKKRLAMATREKQLDALGMRTNEKGQVTAKGSILQKIEKLRDETGLTCFICREGYACQPDKVLGIYTFTKRCNVEEFELKSRKTIGYTTVTHFNVVHVDCHTSAIRLTRGRDEWERASLQNANTRCNGLLPLWGPAVGEAAFSACMTRHSSYMQESTQRCDISYTSSVHDLKLLLVRFAWERSFHDDAGGGGPQSNMHFVPYLLFYSVYLLLSSRSAARDSKTLLTYLQAPPSEKWLECGYEVDGPLFMATISLSLHSRELWNKHKLAHLKRMIAVAQGRHVSPAVLCKALLAPADRQVKDYTVYKPFLMMWALVDLIYDNLFKTVSTPKEEDWPISLFDYLRKNDEALLKSTDSILQTLTEEFLPCTSFVEFCDVAGLLHLIEHPDNFIEEILAALPSTSSSN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *** . * .*:.*: *:: :*: :*: :: ..* :::..:.:: **::*.**::. : : * :.*: .: * ***.* : ** . ... . * *: :* ** * *. :.:: :.*: **.* *::... ..... ... . : *. . .:*:**: . . : .:* :: ** :** .* :.** **:.** : ** .:: ::: ... : :* * .:****:..:: :: *:*: :: :* ::**.*.*: ::: .::.** .* .: . ::* :. *. * ::.**.. ..:*:*.:*.:**:*.****. **: :..* * :**. *:* *:..: : * :. :.... ... : . : * . .::. * :**** *.. :***:****:.*::**:*** :. : ** :.*: : :* :*: *::::..* :*: * :.:*:***.*:* *. ..:. : :**.**::*.:*.:::.. :****. ** **:**:**.... ::..: . ::. ::.. .:*. : .**:.*: *: : : *: ::: *:...:::::* :*.***:.*:* ::..**: *:.* :: *.*:::.* * .**..***:*.::* * .. **: ::*. **** ::**: : . *:.**.*:: *: : . .. . :: ****:** *:**::**.:. ::::* : . : . * : *:*:**.::**::: :** *::**: **:: . . *. . : :::***: * . .: :* **.:: :.. : :**. . :.:: :** : :* :*: : :. :::.* : : *::** * : *:: ****.::::.* . **:* ** ** ::: : . *::*** .: * :* .. ::* : .* : :: .. :* :. :*:: : * * .. * * .: . . * :* .: .. *.: ** : . *: . . : * . :: . ::: :* ::. .: . :: : :**:*: .: ** .. * *.** : **: * ... . :*** * *:::* *: : .*: : *:. :*: *: .. .*..**. .: :**::: **.:: :.: *.*. ::*::* *: : * **.. . :**.:**. .*.*. :::: :. .*...:..::*:*..:****: :: : . * .:::** *: **: ** :: .* *. ****: :: .* ** :.. :*:::*:..: . .:: . * * : . :* .*.::: :* ***.*. . **: *..::: ** .* * .** * .. : **::: ::: ..: .: .:* ::*. : * *:** :*****:* ******: ****************:*:: ****:***:****.*::******.************* . * :* *. : .: . . . : :* *..: :* *. : : : : :* ** * * . :*: : :*: :*: * * **. .** **..** :: .::*****..************************::*:*: *:****:* *********:*********:*:***********:********:*:***:. **:**:.***:** *******:**:*****:**..:*:*::*** .**:* **:******* **::*:*:******.:*: ** :*:*:. .**** **:::: *: :: ::*:**:*** ::: * * :* *****.**:.*:.:** .::.*****:****.**:**:**. *:** :.::. . . :: :: :.:. .:...* .* **:** .***** . **:. *:::*:.* : :****: .**::* *:*.***:... ::**::**********: *: * **:**.*.:** . * *. : :.. *:*.:* * .**:***** : *::**********:** *::* ** ****:**.*:..***:*: **. .:*:.*:*: :*** ::***. : *:***: : *:****:*:**** **:*: *.:.:. : ** **::*.:::***:** .*****. : ..: ... .. . *:. .. * *: *:. **.::..: : : * : *: ** :*:* ** *:: :**:*: :*: **.:** **. . : *:: . : :::**:.* ***: .*.** **:.*.:: .. .:: *: . :** .*. . ** : *: *:.**:*::*:. .: . :. :* ::::* . :*.:.*:*** :* ** ***:*:: :.* ..** ... : :* . .*.: . . . . : : :*. .: .. *.: : ***::.* *** :*.:* *****:::::********. .:.: *.*. .:::: *.. : :..* . :.*****..************: .** *******.::*:. ..*.*** :** : . * .: ... . .: .. * . . . :.: : .: :** :*: :** ::* * : .*::*** :**********:*::*:*: .*.:**: *: : : *:..: : * :.. ***:*.:: *:.*:*.:*** .. :.**:::.:** .* . **. *.*..*::** .** .*. : . :* ***** . .. **:* :: ::*:* : .*:**:* ****:::****** :::.: . . * .: : *.**:*:: ..::********::*******:* ** *:**:*.* :*:: : : : . :. . *.**:*:.* ***::* **: ** ******: .:..* :*:::: : :*:****:::***..*:*. . .:*. . .. *.**:. . : .:**.:: : *: * * ::* *: ::* . :*:*:* ****.* :.:*****.: ::.::.: *:* **:::* :** :*:***::*********::*.* . ::* *: .:**::** **.:* :***: **.**. :::.:*:****:***********:. ***.*:* *::**** : **: .*****: *:*.************:*****:***:*****:** ****:.*.* ..***:***:****.*.******:**:*. ..*:*.********:*** ***********:******:***********::*******:*** :**: ********. *** *:*: *:: *::*** *:**: :: ** *: ** * ... : . .. :::.**: * ***:*. :.:.**:*****:*** *.*.**: ** :*:: .. .. *. *. :.::.:***** * * :*:*****:* * * * ***: ** ::*****: ::****:*: :**:*:.** :: :*: :*. ** * . .* :::: ** ** :.::. *** :*: :.**: .: * : ****:*:** * * ** *:.... * ::* : .: .: : **: : : .* **.* :* . . .... *: *:: :* *** :*:: : : . * :: :*:: :**.. :: .** **:::.:*: .*:**.*::***:*..:. ***.:**** **::: * **. :***. :.:*:: **::: :** :**:**. ****:. . ** ::* .*:* :*:*::*.**:.**.**.**:***:***::*: *********:***.**:*** : *:*.:: .::* :****:**** ***:***:: :**::**************** ****.*.* *:******:***** **:*:******.***************.* :****** . . : :.***:**************:*:*:..::*: * *::*:**.*:*:*.**. **:*:..:: :.:.*.*: ****** ****: :: * : * .::*.:* .*::.* :*::* :* :::**:*.*** **.:: ::.:.. * *. : : *:. : **.*****: *:*::. * :*: ** :* *:** .*:::*:::: :::. *: ** :: *::*. * *** *:. **.: :* *:.:: *..* *:* *:*::**:* :***:* **: :* **: *..* *. :*:******** :*:********* .. . ::: .* *******:*** *:* *.:*** *******.:* ::*:::*:* :*.**** ****** ** *********** :**:* *.** **:**:***:** *** :*:**:***:*** *:******:******:*** * *:**::*::**.:*:**.* : : :* .:** ***::*** *:** *:**** :**:*::**::. :*:* ::*:::*:.*.* :*: * *** * .::**** ::: ::: : . * *. :: *:*::..::.* *:*. : :*: **:*:.*:. *::*.******: : *. :: .* .*. ** :*:*:** .: :::: *::: :*::* :* ** *..*** * .*: *::::* ::* ", "identical_positions": 1876, "similar_positions": 1809, "identity": "33.54%" }, { "cls_id": "homologset.agr.FB:FBgn0011232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMK8-1", "uniprot_id": "VPS54_RAT", "id": "Q9JMK8-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "---------------MASSHSSSPVPQGS--------------------------SSDVFFKKEVDPTKHVR---------------------PVQSLPDVCPKEPT------------VTDQHRWTVYHSKVN---LPAALNDPTLAKRESDFFTKTWGLGFVDTEVIP-SLYLPQIS---KEHFIAYQQEISQREKIHERCKNI--------CPPKDTFDRTLLHIHD-----KSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGNRDAASS---KLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLKKTSQAVKMLRDKIAQIDKVMCEGSLQILRLALTRNNCVKVSNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGVHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEG-----ECQVLEEERLVSLVFGLLEQRKLNFLEIYGEETIITAKNIIKECVINKVAQVEEIDTDAVVKLADQMRMLNFPQWIDLLKDIFSKFTIFLQRVKATLNVIHSVVLSVLDKNQRTRELEEVSQQRSAGKDNSLDTEVAYLTHEGLFISDAFSEAEPASAAVDTTSQRNTSPHSEPCSSDSVSEPECTTDSSSSKEQTPASATLGGVDIIVSEDMRLTDLELGKLASNIQELLCNASDVCHDRAVKFLMSRAKDGFLEKLNSTEFIALSRLMETYIVDTEQICGRKSTSLLGALQSQANKFVNRFHEERRTKLSLLLDNERWKQADVPAEFQDLVDSIADGKIALPDKKPAATEDRKPADVLVVEGHQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLTDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPRKQWSLLRHFDHITKDYHDHIGEISSKLIAIMDSLFDKLLSRCEVEAPAPSPCFRNICKQMTKMHEAIFDLLPKEQTQMLILRINASYKFHLKKQLSHLNVINDGGPQSGFVTADVAFYTGNLQALKGLKDLDLN---MAEIWEQKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SPW0-1", "uniprot_id": "VPS54_MOUSE", "id": "Q5SPW0-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "---------------MASSHSSSPVPQGS--------------------------SSDVFFKKEVDPTKHIR---------------------PVQSLPDVCPKEPTGDSHTLCVAPSLVTDQHRWTVYHSKVN---LPAALNDPTLAKRESDFFTKTWGLDFVDTEVIP-SLYLPQIS---KENFIAYQQEISQREKIHERCKNI--------CPPKDTFDRTLLHIHD-----KSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGSRDAASS---KLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLKKTTQAVKMLRDKIAQIDKVMCEGSLQILRLALTRNNCVKVYNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEG-----ECQVLEEERLVSLVFGLLKQRKLNFLEIYGEEMIITAKNIIKERVINKVSQIEEIDTDVVVKLADQMRMLNFPQWIDLLKDIFSKFTVFLQRVKATLNIIHSVVLSVLEKSQRTRELEEIPQQRSAGKDSSLDTDVAYLTHEGWFISDAFSEGEPASAAVDTTSQRNTSPHSEPCSSDSVSEPECTTDSSSSKEQTSACAPPGGIEIIVSEDMRLTDLELGKLASNIQELLCNASDVCHDRAVKFLMSRAKDGFLEKLNSTEFIALSRLMETFIVDTEQICGRKSTSLLGALQSQANKFVNRFHEERRTKLSLLLDNERWKQADVPAEFQDLVDSIADGKIALPEKKPVVTEERKPADVLVVEGHQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLTDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPPKQWSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSPCFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLN---MAEIWEQKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P1Q0-1", "uniprot_id": "VPS54_HUMAN", "id": "Q9P1Q0-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "---------------MASSHSSSPVPQGS--------------------------SSDVFFKIEVDPSKHIR---------------------PVPSLPDVCPKEPTGDSHSLYVAPSLVTDQHRWTVYHSKVN---LPAALNDPRLAKRESDFFTKTWGLDFVDTEVIP-SFYLPQIS---KEHFTVYQQEISQREKIHERCKNI--------CPPKDTFERTLLHTHD-----KSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGNRDAASS---KLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLRKTSQAVKMLRDKIAQIDKVMCEGSLHILRLALTRNNCVKVYNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLED-----DCQVLEEERLISLVFGLLKQRKLNFLEIYGEKMVITAKNIIKQCVINKVSQTEEIDTDVVVKLADQMRMLNFPQWFDLLKDIFSKFTIFLQRVKATLNIIHSVVLSVLDKNQRTRELEEISQQKNAAKDNSLDTEVAYLIHEGMFISDAFGEGELTPIAVDTTSQRNASPNSEPCSSDSVSEPECTTDSSSSKEHTSSSAIPGGVDIMVSEDMKLTDSELGKLANNIQELLYSASDICHDRAVKFLMSRAKDGFLEKLNSMEFITLSRLMETFILDTEQICGRKSTSLLGALQSQAIKFVNRFHEERKTKLSLLLDNERWKQADVPAEFQDLVDSLSDGKIALPEKKSGATEERKPAEVLIVEGQQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLSDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPPKQYSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSACFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLN---MAEIWEQKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLC0-1", "uniprot_id": "VPS54_DROME", "id": "Q9VLC0-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "------MATTRSAGGAATSVDTGPAAGNSGIRKLSTASVGGIAGGVAPSWQSCYYCTREHFKSISDFVNHLRNRHCTREGGSFVCRYGFNGVCASLPLDGVSDRDYDAHVAKYHVNQHTREMPPEWGVYSAAQN---LPAVLNDPSRGK-QSNLFTKKWGEHFVERSHVPPSPRLPDIT---HADFTVYLGSIGKRYRWHERRQQQ--------LERDKPLENGAQGAPGPGTGGQTPTHLSSVPEIFLKSQLQLHHPATFKQVFPN-YMQTSASSPESHQQTG---RQLQEQLSHYLDMVEVKIAQQVSQKSAAFFHAMTTQHAILAEMEQAADQVRQLRAALAELHSHSVVDSFKVLRFAQRRQHYNLTLDKLRLMATVHKTQPMLQLLLGTQDYVAALDLIGTTQEILSAELLGIHCFKHLPMQLSEMEKLIDKMLTTEFERYAAADLNRPLTDALRETDSVCAEEDKLVAIVMGLLRKQNFSFVQAYQQEAIATIRAIIKQLLIEVLARSDSDQEISLTGHGEQALELTLPEWIALLQRSSQALVSILERIKTVVGIMQQTADAAVG------------------------------------------------------------------AQDAVN--------------------------LIDSEAFLSPGHHEQLKNQLQQLLQAVCHYCHERCANIVSPQSLE--RSSASEQELFQLSEIVDHFGETTRSICGVASVPLQLALKVQASRYAQRFHSERKQKLSLLLDQERWRQVDIPHEFQRIIERMAAGDYAKPEMGNLISNGAGNPVLLVEGKQPYTLVSASLMLIRMLYEYGCSAHRLPLLASYHARNVVDLLRCFNSRSCQLIIGAGAMRVAGLKTITSTNLALVSRALQLVLWLLPKLKEHFQAMSG---------YETIERDYQGHIKEIENKIHGIVSERLAAQLDAWEARPPIPSQTFRHISRHLVKLHEAIAGVLPEAQIHEIYGVVHRNFKDKLREQLLKLNVNNNGGPQHGVVTSELTFYMETLRTLKALPAEQLDNGILEEIWLY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12071-1", "uniprot_id": "VPS54_YEAST", "id": "Q12071-1", "name": "Vacuolar protein sorting-associated protein 54", "aln": "MSISETPHNKSQGLQKAAGRPKIVVPEGSPSRN----------------------SDSGSFTIEGDTSLNDDLLSISG------------SVTPRARRSSRLSLDSITPRRSFDSRTLSVANSRSFGFENETHSGSMDFSPLGNNSIYEIVMNTRRKNWLNYPTVADIPQVSLSKNDLDDHWKTHVIEYVKNIKSDYQIFQSTNNIRNMNQMEQLKELREGENMHEESFEANLRQGDAELINSIPDFYFSDKFQLDNPRTFHKVLDAIDLFLTKLDMKRQAERDEAFSELRDRLNDFLDIVETLLVTEISKSSHKFFHALSEVDNIQKRALDTMSELKELAQNIKTIDAENIRKKISHLEMIFKRKNVEKLEQGLLQAKLVLNKTDECKSMYEENKLDNCLELIKSIDYLIKGDDS------------------INEDVQSWTRCWPYKLSNLRTIP------ALSATREFLTNMKIEIGGKFSLQLSILLIDDLRSFCKSIKPKETLHRIQTGSNDKKQTIFTDNFSSKITELIVRLNRCEELTSAFDLYREKSITELKSIIKIYLPTEN------------------------------------------------------------------AHADNN----------------------------HDEKHLNNGSTS--GSKLSRLIKEQTPAEFQSMLVNIFTHALEALRRLYGHQKLLLDISLNELASVKSPNENQHN---MITQLDIRTG--INEIIRIIQLRTGKIIAVRRELNLSLRYDYFLKFYAICVIFIQECEVLSGEFLTKYLSNVLASQIKHYANAQSSKNYRNIKKKIDAEEWIPYIVDSSIQSDVNDIVSSIDIDPLSWTT---ILDMVGGSHDCENGRSEDKEKDEGNETYQGHRKSVVVGDKTFVASSSLLATIEVIKELMVLSINLPSIYLSNFEKLCYDALQYYNSSAMASVTQPGNSLLKTGRNLSIMGESLDCLAEFVIIVQRFYQRLSNSNRDFEPFDASHYTTLLGQFQASSNKIYMANAPPPPV-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. . .. .* . *. * : . . : : . . : *.: : : *.* . . * :: : .. * .* . : .: :: :. :..:*.:::. .: *... **:.*: : : . . . . *:::*..:**:**. :. ::* * ****:: . : .: . :: * : :. .: *.: *:: : * * :. : : .. .*:** : : ::. : *:: : : :. * . .: * : : : : .:.: :. : * : :. : .. . : . : : : . : :: : : : . .. : . .: *. .::..*: .: : .:: : . ::: : : : . : *. :: :.: : : . :: .* : .: :: . :. : . :* : *: . : .: : : : : *:: :: . . : :.* . .. : .. : : . . : :: :: . ... *. : . . : : : . : * : . : ..:: ::. : . ::. :* . . ", "identical_positions": 50, "similar_positions": 262, "identity": "4.67%" }, { "cls_id": "homologset.agr.FB:FBgn0011236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLP0-1", "uniprot_id": "D3ZLP0_RAT", "id": "D3ZLP0-1", "name": "Zinc finger and BTB domain-containing protein 8B", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGGVSVRSARWRRLEPGARAPGPSRAAAAGGEMEAQSYSAKLLGELNEQRKRDFFCDCSIIVEGRI-FKAHRNILFANSGYFRALLIHYIQDS-GRHSTASLDIVTSDAFSTILDFLYSGKLDLCGENVIEVMSAASYLQMN--DVVNFCKTYIRSSLD-ICRKMEK-EAAVAAAVAVAAAAAAA------HQIDSESPSSVLEGTSCGTKSFVSSPVNGEGSLDCT-----RSS----CDDCHPLELVAKDSQGSGASEGDLCIVPRRVEPKVEFDVARVEVETEEQLQQYAAPL--AHAEEVLPSNQALDLTYSSYHVKQFLEALLRN------------------------GAVQSRDDVDHPFSRGLEGRL-EGPGVAVNSVMDVQNDWYREDS-------------------------------------------------GDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSSRPIICKGCRRTFT----SHLSQGLRRFGLCDSCTCVTDPH----DDDDDLMPVNLSLVEASSESHEKSDTD-DWPIYIE---------------SGEENDPAAEDSDDKPYIRPNLAAPEMLT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NAP8-1", "uniprot_id": "ZBT8B_HUMAN", "id": "Q8NAP8-1", "name": "Zinc finger and BTB domain-containing protein 8B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRI-FKAHRNILFANSGYFRALLIHYIQDS-GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMN--DVVNFCKTYIRSSLD-ICRKMEK-EAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPAEGEKSVECL-----RESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRN------------------------SAAPSKDDADHHFSRSLEGRP-EGAGVAMSSMMDVQADWYGEDS-------------------------------------------------GDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFT----SHLSQGLRRFGLCDSCTCVTDTP----DDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVE---------------SGEENDPAGDDSDDKPQIQPNLSDRETLT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96BR9-1", "uniprot_id": "ZBT8A_HUMAN", "id": "Q96BR9-1", "name": "Zinc finger and BTB domain-containing protein 8A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKV-FKAHRNVLFASSGYFKMLLSQNSKET-SQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMT--DVISVCKTFIKSSLD-ISEKEKD-RYFSLSDKDANSNGVER----------SSFYSGGWQEGSSSPRSHLS-PEQGTG---------------------------IISGKSWNKYNYHPASQKNTQQPLAKHEPRKESIKKTKHLRLSQPSE----VTHYKSSKREVRTSDSSSHVSQSEEQAQID------------------------AEMDSTP-----------------VGYQYGQGSDVTSKSFPDD-------------------------------------------------------LPRMRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACK-LICRKCKRHVTDLTGQVVQEGTRRYRLCNECLAEFGIDSLPIDLEAEQHLMSPSDGDKDSRWHLSEDENRSYVEIVE---------------DGSADLVIQQVDDSEEEEEKEIKPNIR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96DT7-1", "uniprot_id": "ZBT10_HUMAN", "id": "Q96DT7-1", "name": "Zinc finger and BTB domain-containing protein 10", "aln": "MSFSEMNRRTLAFRGGGLVTASGGGSTNNNAGGEASAWPPQPQPRQPPPPAPPALQPPNGRGADEEVELEGLEPQDLEASAGPAAGAAEEAKELLLPQDAGGPTSLGGGAGGPLLAERNRRTLAFRGGGGGGLGNNGSSRGRPETSVWPLRHFNGRGPATVDLELDALEGKELMQDGASLSDSTEDEEEGASLGDGSGAEGGSCSSSRRSGGDGGDEVEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTSWLKDFPWLRYSKDTGLMSCGWCQKTPADGGSVDLPPVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQ-----------------------------ESEIPSEEGYCDFNSRPNENSYCYQLLRQLNEQRKKGILCDVSIVVSGKI-FKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMS--EVVQTCRNFIKDALN-ISIKSEAPESVVVDYNNRKPVN--RDGLSSSRDQKIASFWATRNLTNLASNVKIENDGCNVDEGQIE-----NYQMNDSSWVQDGSPEMAENESEGQTKVFIWNNMGSQGIQETGKTRRKNQTTKRFIYNIPPNNETNLEDCSVMQPPVAYPEEN-TLLIKEEP--DLDGALLSG--------PDGDRNVNANLLAEAGTSQD--GGDAG-TSHD-FKYGLMPGPSNDFKYGLIPGTSNDFKYGLIPGASNDFKYG-----------------LLPESWPK-QETWENGESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSL-VHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQPGGQEGVDQG----------------QDTEFPRDEEYEENE--------------VGEADEELVDDGEDQNDPSRWDESGEVCMSLDD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTY8-1", "uniprot_id": "ZBT10_RAT", "id": "Q9WTY8-1", "name": "Zinc finger and BTB domain-containing protein 10", "aln": "---MGPGRRGNGIGGPG-APRLGGLRRGGRRGGRQGVAAPLGHGRPRLAGRRRGGPPASGK-----------EPSDSGLPRGRRRGSRQQWQQSRPPGDLG---------VAPQAFQWAR--AGGRGSGAGRAGGEGVDAGR---GVPELQHRGGGG------------------------------EPGRWQWGGRRQR----SSSRRSGGEGGEEAEGSGVGAGEGETVQHFPLARPKSLMQKLQCSFQTSWLKDFPWLRYSNDTGLMFCGWCQTTPEDVGSVDLPQVGHDELSRGTRNYKKTLLLRHHVSTEHKLHEANAQVLGSQACVTVDGSAVDKPDASEGCLLVGNESEIPSEEGYCDFNSRPNENSYCYQLLRQLDEQRKKDILCDVSIVVSGKI-FKAHKNILVAGSRFFKTLYCVSNKESPNQNNTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMS--EVVQTCRNFIKDALN-ISIKSEAPESVVVDYNNRKPVS--RDGLTSSRDQKIASFWATRNLTNLASNIKIENDGCNVDEGQIE-----NYQMNDSNWVQDGSPELAENESQGKTKVFIWNNMAS---QETGKARRKNQTTKRFVYNIPPNSETIVEDCSVLQPPVAYPEENKALLIKEEPVSDLDGALLSG--------PDGDRTMNTNLLAEACSSQD--AGDAAGASHD-FKYGLMPGTSSDFKYGLLPSTSNDFKYGLLPGAPNDFKYG-----------------LLPESWPT-QEPWENGDSSLIMNKLKCPHCSYVAKYRRTLKRHLLIHSGVRSFKCEICGKMFTRREHVKRHSL-VHKKDKKYKCMVCKKIFMLAASVGIKHGSRRYGVCMDCVDKSQPGGQESIDQG----------------QDTEFPRDEEYEENE--------------GVEPDEELAEDGQDQSDAPRWDEPGGAYVSG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZTY1-1", "uniprot_id": "D3ZTY1_RAT", "id": "D3ZTY1-1", "name": "Zinc finger and BTB domain-containing protein 46", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKV-FKAHKNVLLGSSRYFKTLYCQVQKTS-DQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMT--DIVQACHDFIKAALD-ISIKSDASDELSEFEIGTPASNSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHEGGS--------SYGKEDQEPKADGPDDVSSQSLWPGDVGYGSLRIKEEQISPSHYGGSELSSSKDAAIQNSLSEQGSGDGWQPTGRRKNRKNKETVRHITQQVEEDSQAGSPVPSFLPTSGWPFSSRDSNVDLTVTEASSLDSRGERAELYAHH-IDEGLLGGETSYLGPPLTPEKEEALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPKGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTL-VHSKDKKYVCKVCSRVFMSAASVGIKHGSRRHGVCADCAGRGVGTPLDHGGGG-EGSPEALFAGEGPYLEDPDDPRGEVEEELGEDEDEDVAKWKDDVGLAHEDALLGDDKDDEDSPQGPHSPAGEPDKDFAWIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BID6-1", "uniprot_id": "ZBT46_MOUSE", "id": "Q8BID6-1", "name": "Zinc finger and BTB domain-containing protein 46", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDACVVVEGKV-FKAHKNVLLGSSRYFKTLYCQVQKTS-DQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMT--DIVQACHDFIKAALD-ISIKSDASDELSEFEIGTPASNSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHEGGS--------SYGKEDQEPKADGPDDVSSQSLWPGDVGYGSLRIKEEQISPSHYGGSELPSSKDTAIQNSLSEQGSGDGWQPTGRRKNRKNKETVRHITQQVEEDSQAGSPVPSFLPTSGWPFSSRDSNVDLTVTEASSLDSRGERAELYAH--IDEGLLGGETSYLGPPLTPEKEEALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPKGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTL-VHSKDKKYVCKVCSRVFMSAASVGIKHGSRRHGVCADCAGRGVGTPLDHGGGG-EGSPEALFAGEGPYLEDPDDPRGEAEEELVEDEDEDVAKWKDDVGLAHEDALLGDDKDDEDSPQGPHSPSGEPDKDFAWIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UZ6-1", "uniprot_id": "ZBT46_HUMAN", "id": "Q86UZ6-1", "name": "Zinc finger and BTB domain-containing protein 46", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKV-FKAHKNVLLGSSRYFKTLYCQVQKTS-EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMT--DIVQACHDFIKAALD-ISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHDGGS--------SYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQ--VEEGLLGGEASYLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTL-VHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPEDPRGE-AEELGEDDE----------GLAPEDALLADDKDEEDSPR-PRSPPGGPDKDFAWLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O77459-1", "uniprot_id": "KEN_DROME", "id": "O77459-1", "name": "Transcription factor Ken", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEFQRMLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSD--CSTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLSSKCGGLRDRADRRKQQYTSPQNLEPDQTLKYEVDSVDESRNAADFSSAFNSNDNCESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNISTSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSSTINPVNLSLDLRTKSENSASRTLGSGSDHSGIDLAVTASESTKRKGLFFDSHKDVMKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTSYPHSLLEELRLAKSTTSPISGFGSEK----------NMLAHLEDGALNGDTLTPDRKHLLEAQRNRAQSPEIPMHLGPQFVYQWQSNQNAAMSAMPNLQSRLSSLSHISLNLDHPEGRSGSASGSGANLAGSNTHASSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGADTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :* ::. : .* :: ..:: ::**: :* . * :: * ... : *. ::**:**.: : ..:. : **:. . :: . : : . . . . : . * : :. : : : . . :: .*: : . . : . .. . . : . ", "identical_positions": 16, "similar_positions": 75, "identity": "1.63%" }, { "cls_id": "homologset.agr.FB:FBgn0011244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63038-1", "uniprot_id": "CH60_MOUSE", "id": "P63038-1", "name": "60 kDa heat shock protein, mitochondrial", "aln": "MLRLPTVLRQMRPVSRALAP-HLTRAYA--KDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYE-KEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSE---VGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKE-----------EKDP----------------------------GMGAMGGMGGGMG-----GGMF------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63039-1", "uniprot_id": "CH60_RAT", "id": "P63039-1", "name": "60 kDa heat shock protein, mitochondrial", "aln": "MLRLPTVLRQMRPVSRALAP-HLTRAYA--KDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYE-KEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSE---VGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKE-----------EKDP----------------------------GMGAMGGMGGGMG-----GGMF------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10809-1", "uniprot_id": "CH60_HUMAN", "id": "P10809-1", "name": "60 kDa heat shock protein, mitochondrial", "aln": "MLRLPTVFRQMRPVSRVLAP-HLTRAYA--KDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYE-KEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSE---VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKE-----------EKDP----------------------------GMGAMGGMGGGMG-----GGMF------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPS5-1", "uniprot_id": "CH60B_DROME", "id": "Q9VPS5-1", "name": "60 kDa heat shock protein homolog 1, mitochondrial", "aln": "------MFRSCVPKAITSSR-CFARMYS--KDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNIIQGLRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDINYSKMEEAKLEDLGQVGEAVISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQELKTESADLQKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSED---YGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVITDSRNDDLLSKLSGAGGGMDDGLDMNMGGLEELAALSGLGGMGGMGGMGGMGGMGGMGGGFGGMGAGGGMSASASNDGPTAEEMNEMVKAIPGMEQVEVRDIDSGMM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19882-1", "uniprot_id": "HSP60_YEAST", "id": "P19882-1", "name": "Heat shock protein 60, mitochondrial", "aln": "------MLRSSVVRSRATLRPLLRRAYSSHKELKFGVEGRASLLKGVETLAEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKDKFENMGAKLLQEVASKTNEAAGDGTTSATVLGRAIFTESVKNVAAGCNPMDLRRGSQVAVEKVIEFLSANKKEITTSEEIAQVATISANGDSHVGKLLASAMEKVGKEGVITIREGRTLEDELEVTEGMRFDRGFISPYFITDPKSSKVEFEKPLLLLSEKKISSIQDILPALEISNQSRRPLLIIAEDVDGEALAACILNKLRGQVKVCAVKAPGFGDNRKNTIGDIAVLTGGTVFTEELD-LKPEQCTIENLGSCDSITVTKEDTVILNGSGPKEAIQERIEQIKGSIDITTTNSYEKEKLQERLAKLSGGVAVIRVGGASEVEVGEKKDRYDDALNATRAAVEEGILPGGGTALVKASRVLDEVVVDNFDQKLGVDIIRKAITRPAKQIIENAGEEGSVIIGKLIDEYGDDFAKGYDASKSEYTDMLATGIIDPFKVVRSGLVDASGVASLLATTEVAIVDAPEP-----------P-------------------------------AAAGAGGMPGGMP------GMP---------------------------------GMM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*. : . : * *: *:::** ** :::**: **:***.*:*****.*::*:.: .**:****.***:** ***:. *:****:*:**.:*** ******:****.*:* .*..:::: *.**:::*** :**: * *. .* : * *** ****:*****..:*.::..* .*** .*.**:::*: *:***:: :*::**.*::**:*:. .*..* ** .. :::* ***:.:..*: .** : *:**:*****:.**** : :**:*: ::* ***:*.:*.:**: : *:: **.::* :: : *: .:**. .. ::*:.:::*:*. . :: **::* .: . : :::*.:**: *: ****:::** *:***.***** *********:****: *** *:::. *:.: . * : *::*: .:: *. * :*** :*.::: *::: : **** .:: :: .***** **:*:.: **:******:*:*..:.: : . .. *** **: ** ", "identical_positions": 228, "similar_positions": 209, "identity": "34.55%" }, { "cls_id": "homologset.agr.FB:FBgn0011259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTL3-1", "uniprot_id": "SEM6C_RAT", "id": "Q9WTL3-1", "name": "Semaphorin-6C", "aln": "-----------------------------------------------MPRAPHSMPLLLLLLLS--LPQAQTAFPQDPIPLLTSDLQGTSPSSWFRGLEDDAVAAELG---LDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQ--DMENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELS-GQARCPFDATQSTVAISAEGSLYSATAADFQASDAVVYRSLG-PQPPLRSAKYDSKWLREPHFVYALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQSLTGPVN----LHGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAAALFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLT-LTSRALLTQVAVDGMAGPHRN--TTVLFLGSNDGTVLKVLPPGGQ---SLGPEPIILEEIDAYSHARCS-GKRSPRAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQR-SCLASLDPYCGWHRF-RGCVNIRG---PGGTDVDLTGNQESMEHGDCQDGATGSQSGPGDSAYVLLGPGPSPETPSSPSDAHPG--------------PQSSTLGAHTQGVRRDLSPASASRSIPIPLLLACVAAAFALG---ASVSGLLVSCACRR-------ANRRRSKDIETPGLPRPLSLRSLAR-----LHGGGPEPPPPPKDGDAAQTPQLYTTFLP--------------------PPEGGSPPELACLPTPETTPELPVKHLRASGG-PWEWNQNGNNASE------GPGRP---------------RGCSAAGG---------PAPRVLVRPPPPGCPGQEVEVTTLEELLRYLHGPQPPRKGSEPLASAPFTS-----------RPPASEPGAALFVDSSPMPRDCVPPLRLDVPPDGKRAAPSGRPALS-APAPRLG----------------VSGSRRLP-----------FPTHRAPPGLLTRVPSGG---------PSRYSGGPGR-------------------HLLYLGRPDGHRGRSLKRVDVKSP-LSPKPPLATPP--QPAPHGSHFNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTM3-1", "uniprot_id": "SEM6C_MOUSE", "id": "Q9WTM3-1", "name": "Semaphorin-6C", "aln": "-----------------------------------------------MPRAPHSMPLLLLLLLLSSLPQAQAAFPQDPTPLLTSDLQGASPSSWFRGLEDDAVAAELG---LDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQ--DMENCAVRGKLTDECYNYIRVLVPWNSQTLLACGTNSFSPMCRSYGITSLQQEGEELS-GQARCPFDATQSTVAIFAEGSLYSATAADFQASDAVVYRSLG-PQPPLRSAKYDSKWLREPHFVYALEHGEHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQSLTGPVN----LHGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAAASFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLT-LTSRALLTQVAVDGMAGPHRN--TTVLFLGSNDGTVLKVLPPGGQ---SLGSEPIVLEEIDAYSHARCS-GKRSPRAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQR-SCLASLDPYCGWHRS-RGCMSIRG---PGGTDVDLTGNQESTEHGDCQDGATGSQSGPGDSAY----------------------------------------------GVRRDLSPASASRSIPIPLLLACVAAAFALG---ASVSGLLVSCACRR-------ANRRRSKDIETPGLPRPLSLRSLAR-----LHGGGPEPPPPPKDGDAAQTPQLYTTFLP--------------------PPDGGSPPELACLPTPETTPELPVKHLRASGG-PWEWNQNGNNASE------GPGRPP--------------RGCSGAGG---------PAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGSEPLASAPFTS-----------RPPASEPGASLFVDSSPMPRDGVPPLRLDVPPEGKRAAPSGRPALS-APAPRLG----------------VGGSRRLP-----------FPTHRAPPGLLTRVPSGG---------PARYSGGPGR-------------------HLLYLGRPEGHRGRSLKRVDVKSP-LSPKPPLASPP--QPAPHGGHFNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3T2-1", "uniprot_id": "SEM6C_HUMAN", "id": "Q9H3T2-1", "name": "Semaphorin-6C", "aln": "-----------------------------------------------MPRAPHFMPLLLLLLLLS-LPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELG---LDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELS-GQARCPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLG-PQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVN----LHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLT-LTSRALLTQVAVDGMAGPHSN--ITVMFLGSNDGTVLKVLTPGGR---SGGPEPILLEEIDAYSPARCS-GKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQR-SCLASQDPYCGWHSS-RGCVDIRG---SGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAY----------------------------------------------GVRRDLPPASASRSVPIPLLLASVAAAFALG---ASVSGLLVSCACRR-------AHRRRGKDIETPGLPRPLSLRSLAR-----LHGGGPEPPPPSKDGDAVQTPQLYTTFLP--------------------PPEGVPPPELACLPTPESTPELPVKHLRAAGD-PWEWNQNRNNAKE------GPGRS---------------RGGHAAGG---------PAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGAEP--PAPLTS-----------RALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALS-APAPRLG----------------VGGGRRLP-----------FSGHRAPPALLTRVPSGG---------PSRYSGGPGK-------------------HLLYLGRPEGYRGRALKRVDVEKPQLSLKPPLVGPSSRQAVPNGGRFNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HGM6-1", "uniprot_id": "A0AC58HGM6_DANRE", "id": "A0AC58HGM6-1", "name": "", "aln": "MAAERAAWRNGLSGLICTTTLRWSSVYSGSCCVAEFYAVAEMRLVILGSRPLLALTLMLTLTCLKHLCHGATPFPQDLEPIRTVGSEHTYLYPSFQGNMSDNDTARLG---LDFQRMLRINHMVYIAARDHVFAINLSASLER--IVPQQKLTWKTK--DVEKCTVRGKNSDECYNYIKVLVPRNDETLFACGTNAFNPTCRNYKMSSLEQDGEEVI-GQARCPFESRQSNVGLFAGGDFYSATMTDFLASDAVIYRSLGESSPVLRTVKYDSKWLREPHFLHAIEYGNYVYFFLSEIAVEYTTLGKVVFSRVARVCKNDNGGSPRVLERYWTSFLKARLNCSVPGDSFFYFDVLQSLTNVMQ----INHRPAVLGVFTTQANSITGSAVCAFYMDDIEKVFNGKFKEQRNSESAWTPVPDEAVPKPRPGSCAGDGPAAGYKSSTNFPDETLTFIKSYPLMDEAVPSVNNRPCFTRTTSRFKLTQIAVDTAAGPYKN--YTVVFLGSENGHVLKVLASMHP---NSSYSTQVLEDIDVYNPNKCN-VRG---EDRRILGLELDKDHHALFVAFTGCVIRVPLSRCSDYGICRK-SCLSSRDPYCIWLSA-GNCATVAPGFKSGFEQYVESGYPQYPDSCHDVLATTRKQNPAVDSAYGKTSPTSASTTNQGPAGAPETGTHPEEGRRGGQGSPDLEPGSVEMEGVRRPPEVDKSNHSVHYTLLIACVLVAFVLG---AFLSGFLVSCYCNHN----VNKTKRLSKDPEAP-IPHALSLRSLAK-----LNG--LLESQNKDEKLEVSSPKLYNSFFANGKEQAHRRNAHHAAMTELIHPHHHHSAELSGLPTPDSTPELPIKSMKAFKN-QWEKNQNCNNAKEPKSHNMGASRPTSAMQHQMFPFSHGLTNGQVLGGSVHMDERKVHNTERVVSQPYHCYPHKIVDVTSLDELLKHIHEINVATGKSPSVLTSSMSANAGQMAFANRVQPHIPETESAPYYSSSTLPRDSLT-RRMDIPPEIPPHHQSTLERVSRHPAQRHS----------------LITTPKMPSGGVVPRQHSFNQRSSHQPLLLSRMNSNGSNSGCDVRHPLIPNGYLTR-------------------QHSYSEQPEVHRGAIVRRTASLKPDVPPKPLFIPAS--SPVNQAGKFNY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZAG0-1", "uniprot_id": "D3ZAG0_RAT", "id": "D3ZAG0-1", "name": "Semaphorin-6A", "aln": "------------------------------------------------------MRPAALLLCLTLLRCAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQR--HRLDIQMIMIMNRTLYIAARDHIYTVDIDTSHTEEIYCSKK-LTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDTLFVCGTNAFNPSCRNYRVDTLETFGDEFS-GMARCPYDAKHANIALFADGKLYSATVTDFLAIDAVIYRSLG-DSPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR----INGRDVVLATFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLEKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNTAGPYEN--HTVVFLGSEKGIILKFLARIGS--SGFLNGSLFLEEMNVYNPEKC---SYDGVEDKRIMGMQLDKASGSLYVAFSTCVIKVPLGRCERHGKCKK-TCIASRDPYCGWVKETGSCAHLSPLSRLAFEQDIERGNTDGLGDCHNSFVALNGRASSLYPSTTTSDSASRDGHESQGGMLDWNDLLKAPGNTDPLG-AVSSHNHQDKKGVIRESYLKSNDQLVPVTLLAIAVILAFVMG---AVFSGIIVYCVCDHR-RKDVAVVQRKEKELTHSRRGSMSSVTKLS--------GLFGDSQSKDPKPEAILTPLMHNGKLAT-----------PSNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPNRGSREWERNQNLINACT--------------------------KDMPPMGSP------VIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVVAQMALEDQAATLEYK-TIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPTGASLSQTGLSKRLEMQHSSSYGLEYKRSYPTNSLTRSHQATTLKRN------------NTNSSNSSHLSRNQSLGR--------GDNPPPAPQRVDSIQVHSPQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35464-1", "uniprot_id": "SEM6A_MOUSE", "id": "O35464-1", "name": "Semaphorin-6A", "aln": "------------------------------------------------------MRPAALLLCLTLLHCAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQR--HRLDIQMIMIMNRTLYVAARDHIYTVDIDTSHTEEIYCSKK-LTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDTLFVCGTNAFNPSCRNYRVDTLETFGDEFS-GMARCPYDAKHANIALFADGKLYSATVTDFLAIDAVIYRSLG-DSPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR----INGRDVVLATFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLEKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNAAGPYQN--HTVVFLGSEKGIILKFLARIGS--SGFLNGSLFLEEMNVYNPEKC---SYDGVEDKRIMGMQLDRASGSLYVAFSTCVIKVPLGRCERHGKCKK-TCIASRDPYCGWVRESGSCAHLSPLSRLTFEQDIERGNTDGLGDCHNSFVALNGHASSLYPSTTTSDSASRDGYESRGGMLDWNDLLEAPGSTDPLG-AVSSHNHQDKKGVIRESYLKSNDQLVPVTLLAIAVILAFVMG---AVFSGIIVYCVCDHR-RKDVAVVQRKEKELTHSRRGSMSSVTKLS--------GLFGDTQSKDPKPEAILTPLMHNGKLAT-----------PSNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPNRGSREWERNQNIINACT--------------------------KDMPPMGSP------VIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVVAQMALEDQAATLEYK-TIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGTSLSQTGLSKRLEMQHSSSYGLEYKRSYPTNSLTRSHQTTTLKRN------------NTNSSNSSHLSRNQSFGR--------GDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2E6-1", "uniprot_id": "SEM6A_HUMAN", "id": "Q9H2E6-1", "name": "Semaphorin-6A", "aln": "------------------------------------------------------MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQR--HRLDIQMIMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKK-LTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFS-GMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLG-ESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR----INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQN--HTVVFLGSEKGIILKFLARIGN--SGFLNDSLFLEEMSVYNSEKC---SYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKK-TCIASRDPYCGWIKEGGACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGMLDWKHLLDSPDSTDPLG-AVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMG---AVFSGITVYCVCDHR-RKDVAVVQRKEKELTHSRRGSMSSVTKLS--------GLFGDTQSKDPKPEAILTPLMHNGKLAT-----------PGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERNQNLINACT--------------------------KDMPPMGSP------VIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEV-AQMALEDQAATLEYK-TIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRN------------NTNSSNSSHLSRNQSFGR--------GDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70141-1", "uniprot_id": "SEM6B_RAT", "id": "O70141-1", "name": "Semaphorin-6B", "aln": "----------------------------------------------MWTPRAPPPRPALLFLLLLLLRVTHGLFPDEPPPLSVAPRDYLSHYPVFVGSGPGRLTPAEGAEDLNIQRVLRVNRTLFIGDRDNLYQVELEPSTSTELRYQRK-LTWRSNPSDIDVCRMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPICANYSMDTLQLLGDNIS-GMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLG-DRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVS----LGGRPVILAVFSTPSNSIPGSAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPG--MQYNASNALPDEILNFVKTHPLMDEAVPSLGHSPWIVRTLIRHQLTRVAVDVGAGPWGN--QTIVFLGSEVGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRSSSAGEWGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQLYSGCMK-NCIGSQDPYCGWAPD-GSCIFLRPGTSATFEQDVSGASTSGLGDCT---------------------------------------------------------------GLLRASLSDDRAGLVSVNLLVTSSVAAFVVG---AVVSGFSVGWFVGLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGTGGRGGAGGGPGGPPEALLAPLMQNG-----------------WTKAALLHGGPHDLDSGLLPTPEQTP-LPQKRLPTTHP-----------------------------------------HAHALGPR------AWDHSHALLS-ASASTSLLLLAHTRA---------PEQPPVPTESGPESRLCAPR---------SCRASHPG-----DFPLTPHASPDRRRVVSAPTGPLDSSSVGDDLPGPWSP------------------PATSSLRRP------------GPHGPPTAALRRTHTFNS--------GEARPGG---------HRPR---------RHAPADSTHLLPCGTGERT------APPVP-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24322-1", "uniprot_id": "SEM1A_DROME", "id": "Q24322-1", "name": "Semaphorin-1A", "aln": "-----------------MLNSHNTNHNNNSASNSNYNKGHKMHLKSATAKATIMKHKLSKFYGYGWMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLKFVGNESVVDHFKLVTKDGNSLLIGARNTVFNLSIHD------LVEQQRLVWTSPEDDTKMCLVKGKDEEACQNYIRIMVVPSPGRLFVCGTNSFRPMCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIY------REPLQTEQYDSLSLNAPNFVSSFTQGDFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGG-PHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSCHNDS--------RALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESAD-SADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGFRN-------------------------------DMDLLDSRRQSKDQEIIDNIDKNFEDIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFCGRR------CHKDEDDNLPYPDTEYEYFEQRQNVN---------SFPSSCRIQQEPKLLP----------------------------QVEEVTYAEPVLLPQPPPPNKMHSPKNTLRKP-----------------------------------------------------------PMHQMHQGPNSETLFQFQPDGYNTQQSYRGRDNFGTLRSHQVMGDNYRRG----------DGFSTTRSVKKAVNNTNTRNRSLGRARRQPPRHGIVTQHRSNSPQQQQQQSQQP--------------------------------------HSSSGSSPVMSNSSSS--------PAPPSSSPSP-------------------QESPKNCSYIYRD------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * .:: . . : :. *: :: ..: .: *.* : * . * ::** * *:::::: . *:.**:*:* * * .* : : : * * **::. : . .: : . :::.* :** . *.::* *:: ::** :. * *: :. *..:***: * ::* :. .***:*** * ** : : . ****** *****:*** ***: :*: :. : : ..*.* ***.******: : :: * *:*:** . :. * ** : ** ****.* . :** * *:*::.*:* **. * : :*::*** . . ::*:*:: * ::* : . .:*::.. . : : . * . :: : : ** *:. **** * * : *. * : . *: . : * : ** * . : . . : : . . . : . : ", "identical_positions": 127, "similar_positions": 162, "identity": "10.74%" }, { "cls_id": "homologset.agr.FB:FBgn0011260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H3S1-1", "uniprot_id": "SEM4A_HUMAN", "id": "Q9H3S1-1", "name": "Semaphorin-4A", "aln": "------------------------------------MALPALGLD-----PWSLLG----LFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQD-------FDTLLLSGDGNTLYVGAREAILALDIQDPGVPR---LKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVT-HLYTCGTFAFSPACTFIELQDSY--------------------------------LLPISEDKVME--GKGQSPFDPAHKHTAVLVDGM-------LYSGTMNNFLGSEPILMRTL---------GSQPVLKTDNFLRWLHHDASFVAAIP---------STQVVYFFFEETASEF------DFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ-L---PFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKG----KYKELNKETSR-WTTYRGP-ETNPRPGSCSVGPS-------------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEYTR-LAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD-------SSAHLVEEIQLFPDP----------EPVRNLQLAPTQG--AVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNS--WKQDMERGNPEWACAS---------------------------------------------------------------------------GPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWS-HGPAAVPEASSTV----YNGS---LLLIVQDGVGGLYQCWATEN----GFSYPVISYWVD--------------------SQDQTLALDPELAG-IPREHVKVPLTRVSGG-AALAAQQS---------------------------------------------------------------------YWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCETL-------------R--------PGEKAPLSREQHLQSPKECR--TSASD----------------------------------------------------------------------------------------VDADNNC------LGTEVA------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NPR2-1", "uniprot_id": "SEM4B_HUMAN", "id": "Q9NPR2-1", "name": "Semaphorin-4B", "aln": "------------------------------------MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPP---TWALSPRISLPLGSEERPFLRFEAEHISN-------YTALLLSRDGRTLYVGAREALFALSSNLSFLPG--GEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGS-HLFTCGTAAFSPMCTYINMENFT--------------------------------LARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGE-------LYTGTVSSFQGNDPAISRSQ---------SLRPT-KTESSLNWLQDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEF------EFFENTIVSRIARICKGDEGG-ERVLQQRWTSFLKAQLLCSRPDDGF---PFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSG----LYKEVNRETQQ-WYTVTHP-VPTPRPGACITNSARE--RKINSSLQLPDRVLNFLKDHFLMDGQVR---SRMLLLQPQARYQR-VAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSVG--------PRVHIIEELQIFSSG----------QPVQNLLLDTHRG--LLYAASHSGVVQVPMANCSLY-RSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSA---------------------------------------------------------------------------SSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHV----LPTG---DLLLVGTQQLGEFQCWSLEE----GFQQLVASYCPE--------------------VVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRS---------------------------------------------------------------------YWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASV-------------HPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESEKRPL------------------------------------------------------------------SIQDSFVEVSPVCPRPRVRLGSEIRDSVV--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q92854-1", "uniprot_id": "SEM4D_HUMAN", "id": "Q92854-1", "name": "Semaphorin-4D", "aln": "-----------------------------------------------------------MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYN-------YSALLLSEDKDTLYIGAREAVFAVNALN---IS--EKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSAT-SLYVCGTNAFQPACDHLNLTSFK--------------------------------FLGKNED------GKGRCPFDPAHSYTSVMVDGE-------LYSGTSYNFLGSEPIISRN----------SSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEY------EFVFRVLIPRIARVCKGDQGG-LRTLQKKWTSFLKARLICSRPDSGL---VFNVLRDVFVLR--SPGLKVPVFYALFTPQLNN--VGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTK-WVRYNGP-VPKPRPGACIDSEARA--ANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQ-IVVDRTQALDGTVYDVMFVSTDRGALHKAISLE--------HAVHIIEETQLFQDF----------EPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKH-GTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEMSG---------------------------------------------------------------------------------------DASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYG----LMGRKNLLIFNLSEGDSGVYQCLSEER----VKNKTVFQVVAKHVLE---------VKVVPKPVVAPTLSVVQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPT------------------------------------GTSCEPKIVINTVPQLHSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLP-RQCLKF-------------RSALLIGKKKPKSDFCDREQSLKETLVEPGSFSQQNGEHPKPALDTGYETEQ------------------------------------------------------------------DTITSKVPTDREDSQRIDDLSARDKPFDVKCELKFADSDADGD------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9C0C4-1", "uniprot_id": "SEM4C_HUMAN", "id": "Q9C0C4-1", "name": "Semaphorin-4C", "aln": "-------------------------------------------------------MAPHWAVWLLAARLWGLGIG-AEVWWNLVPRKTVSSGELATVVRRFSQTGIQD-------FLTLTLTEPTGLLYVGAREALFAFSMEAL------ELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPYNAS-HLYVCGTYAFQPKCTYVNMLTFT--------------------------------LEHGEFED-----GKGKCPYDPAKGHAGLLVDGE-------LYSATLNNFLGTEPIILRNM---------GPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVES------DCYAEQVVARVARVCKGDMGG-ARTLQRKWTTFLKARLACSAPNWQL---YFNQLQAMHTLQDTSW-HNT-TFFGVF--QAQWGDMYLSAICEYQLEEIQRVFEG----PYKEYHEEAQK-WDRYTDP-VPSPRPGSCINNWHRR--HGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTH-LVADRVTGLDGATYTVLFIGTGDGWLLKAVSLG--------PWVHLIEELQLFDQ-----------EPMRSLVLSQSKK--LLFAGSRSQLVQLPVADCMKY-RSCADCVLARDPYCAWSVNTSRCVAVGG-HSG-SLLIQHVMTS------DT---------------------------------------------------------------------------SGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWT-FGG-RDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQ----GARLAAEGYLVAVVAG--------PSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEK----------------------------------------------------------------------GAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYY-------------SDGSLKIVPG-HARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGY------------------------------------------------------------------VRLQLGGEDRGGLGHPLPELADELRRKLQQR-QPLPDSNPEESSV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NTN9-1", "uniprot_id": "SEM4G_HUMAN", "id": "Q9NTN9-1", "name": "Semaphorin-4G", "aln": "---------------------------------------------------MWGRLWPLLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELS--GTRHFKGQAQN-------YSTLLLEEASARLLVGARGALFSLSANDIG--D--GAHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNST-HLYACGTHAFQPLCAAIDAEAFT--------------------------------LPT-SFEE-----GKEKCPYDPARGFTGLIIDGG-------LYTATRYEFR-SIPDIRRSR---------HPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGG-KKILQKKWTSFLKARLICHIP-------LYETLRGVCSLDAETS-SRT-HFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAG----PYMEYQDGSRR-WGRYEGG-VPEPRPGSCITDSLRS--QGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTH-LTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLG--------SGMHIIEETQVFRES----------QSVENLVISLLQH--SLYVGAPSGVIQLPLSSCSRY-RSCYDCILARDPYCGWDPGTHACAAATT-IANRTALIQDIERG------NR---------------------------------------------------------------------------G--CESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWL-LNGSMGLSDGQGG---YRVGVDGLLVTDAQPEHSGNYGCYAEEN----GLRTLLASYSLTVRPATPAPAPK-APATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVAC-LREGRRG----------------------------------------------------------------------RRRKYSLGRASRAGGSAVQLQTVSGQCPGEEDEGDDEGAGGL-------------EGSCLQIIPGEGAPAPPPPPPPPPPAELTNGLVALPSRLRR-----MNGNSY------------------------------------------------------------------VLLRQSNN---GVPAGPCSFAEELSRILEKRKHTQLVEQLDESSV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O95754-1", "uniprot_id": "SEM4F_HUMAN", "id": "O95754-1", "name": "Semaphorin-4F", "aln": "-----------------------------------------MPASAARPRPGPGQPTASPFPLLLLAVLSGPVSG---RVPRSVPRTSLPISEADSCLTRFAVPHTYN-------YSVLLVDPASHTLYVGARDTIFALSLPFSG-----ERPRRIDWMVPEAHRQNCRKKGKK-EDECHNFVQILAIANAS-HLLTCGTFAFDPKCGVIDVSRFQ--------------------------------QVE-RLES-----GRGKCPFEPAQRSAAVMAGGV-------LYAATVKNYLGTEPIITRAVG--------RAEDWIRTDTLPSWLNAPAFVAAVALSPAEWGDEDGDDEIYFFFTETSRAF------DSYERIKVPRVARVCAGDLGG-RKTLQQRWTTFLKADLLCPGPEHGR---ASSVLQDVAVLRPELG-AGTPIFYGIFS--SQWEGATISAVCAFRPQDIRTVLNG----PFRELKHDCNRGLPVVDND-VPQPRPGECITNNMKL--RHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLVTTDTAYLR-VVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIG--------AQLSVLEDLALFPEP----------QPVENMKLYHS----WLLVGSRTEVTQVNTTNCGRL-QSCSECILAQDPVCAWSFRLDECVAHAG-EHR--GLVQDIESA------DV---------------------------------------------------------------------------SSLCPKE--PGERPVVFEVPVATAAHVVLPCSPSSAWASCVWHQPSGVTALTPRRDG-----------LEVVVTPGAMGAYACECQEG----GAAHVVAAYSLVWGSQ------------------RDAPSRAHTVGAGLAGFFLGILAASLTLILIGRRQQRR----------------------------------------------------------------------RQRELLARDKVGLDLGAPPSGTTS-----------------------------------------------YSQDPPSPSPEDERLPLALAKRGSGFG----------------------------------------------------------------------------------------GFSPPFLLDPCPSPAHIRLTGAPLATCDETSI----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7FHT4-1", "uniprot_id": "F7FHT4_RAT", "id": "F7FHT4-1", "name": "Semaphorin-3C", "aln": "-------------------------------------------------MSKSEEMALREICVLVGVFICSICVQGSSQPQARVYLTFDELRETKTSEYFSLSHQQLD-------YRILLMDEDQDRIYVGSKDHILSLNINNIS-----QEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRT-HLYVCGSGAFSPVCTYLNRGRRS-------------------------------EDQVFMIDS-KCESGKGRCSFNPNVNTVSVMINEE-------LFSGMYIDFMGTDAAIFRSLT--------KRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDP---NDAKVYFFFKERLTDNN------RSTKQIHSMVARICPNDTGG-QRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFT--TSSSVFKGSAVCVYHLSDIQTVFNG-----PFAHKEGPNHQLISYQGR-IPYPRPGTCPGGAFTP---NMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSA---SGELILEELEVFKNH----------VPITTMKISSKKQ--QLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGK----RRSRRQDVRHGNPLTQCR---------------------------------------------------------------------------GFNLKGMRAYRN-AAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDK-DRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATEN----SFKQTIAKINFKVLDS-------------------------EMVAVVTDKWS--------PWTWAGSVRALP-----------------------------------------------------------------------FHP--KDILGAFSHSEMQ--------------------------------------------------LINQYCKDTRQQQQLG-----EEPQKMRGDYG------------------------------------------------------------------------------------KLKALINSRKSRNRRNQLPES----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62181-1", "uniprot_id": "SEM3C_MOUSE", "id": "Q62181-1", "name": "Semaphorin-3C", "aln": "-------------------------------------------------------MAFRAICVLVGVFICSICVRGSSQPQARVYLTFDELRETKTSEYFSLSHQQLD-------YRILLMDEDQDRIYVGSKDHILSLNINNIS-----QEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRT-HLYVCGSGAFSPVCTYLNRGRRS-------------------------------EDQVFMIDS-KCESGKGRCSFNPNVNTVSVMINEE-------LFSGMYIDFMGTDAAIFRSLT--------KRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDP---NDAKVYFFFKERLTDNN------RSTKQIHSMIARICPNDTGG-QRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFT--TSSSVFKGSAVCVYHLSDIQTVFNG-----PFAHKEGPNHQLISYQGR-IPYPRPGTCPGGAFTP---NMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSA---SGELILEELEVFKNH----------VPITTMKISSKKQ--QLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGK----RRSRRQDVRHGNPLTQCR---------------------------------------------------------------------------GFNLK---AYRN-AAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDK-DRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATEN----SFKQTIAKINFKVLDS-------------------------EMVAVVTDKWS--------PWTWAGSVRALP-----------------------------------------------------------------------FHP--KDILGAFSHSEMQ--------------------------------------------------LINQYCKDTRQQQQLG-----EEPQKMRGDYG------------------------------------------------------------------------------------KLKALINSRKSRNRRNQLPES----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99985-1", "uniprot_id": "SEM3C_HUMAN", "id": "Q99985-1", "name": "Semaphorin-3C", "aln": "-------------------------------------------------------MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLD-------YRILLMDEDQDRIYVGSKDHILSLNINNIS-----QEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRT-HLYVCGSGAFSPVCTYLNRGRRS-------------------------------EDQVFMIDS-KCESGKGRCSFNPNVNTVSVMINEE-------LFSGMYIDFMGTDAAIFRSLT--------KRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDP---NDAKVYFFFKEKLTDNN------RSTKQIHSMIARICPNDTGG-LRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFT--TSSSVFKGSAVCVYHLSDIQTVFNG-----PFAHKEGPNHQLISYQGR-IPYPRPGTCPGGAFTP---NMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSV---SGELILEELEVFKNH----------APITTMKISSKKQ--QLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGK----RRSRRQDVRHGNPLTQCR---------------------------------------------------------------------------GFNLK---AYRN-AAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDK-DRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATEN----SFKQTIAKINFKVLDS-------------------------EMVAVVTDKWS--------PWTWASSVRALP-----------------------------------------------------------------------FHP--KDIMGAFSHSEMQ--------------------------------------------------MINQYCKDTRQQHQQG-----DESQKMRGDYG------------------------------------------------------------------------------------KLKALINSRKSRNRRNQLPES----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZGX9-1", "uniprot_id": "D3ZGX9_RAT", "id": "D3ZGX9-1", "name": "", "aln": "----------------------------------------------------MLVTGFILWASLLTGAWPAAPIQDQLPATPRVRLSFKELKATGTAHFFNFLLNTTD-------YRILFKDEDHDRMYVGSKDYVLSLDLHDIN-----REPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNRT-HLYVCGTGAYNPMCTYVNRGRRSQAPPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALINEE-------LYAGVYIDFMGTDAAIFRTLG--------KQTAMRTDQYNSRWLNDPSFIHAELIPDSAER---NDDKLYFFFRERSAEAP------QNPA-VYARIGRICLNDDGG-HCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDV--RNPVIYAVFT--SSGSVFRGSAVCVYSMADIRMVFNG-----PFAHKEGPNYQWMPFSGK-MPYPRPGTCPGGTFTP---SMKSTKDYPDEVINFMRTHPLMYQAVYPLQRRPLVVRTGAPYRLTTVAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQE---VEELMLEEVEVFKEP----------APVKTMTISSKRQ--QLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSK----RRSRRQDVRHGNPIRQCR---------------------------------------------------------------------------GFNSN---ANKN-AIESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPSDRRREIRAEDRFLRTEQGLLLRALQLGDRGLYSCTATEN----NFKHVVTRVQLHVLGR-------------------------DAVHAALFPP--------LAVSVPPPPGTGP-----------------------------------------------------------------------PTPPYQELAQLLAQPEVG--------------------------------------------------LIHQYCQGYWRHVP-------PNPREAPGAL-------------------------------------------------------------------------------------RPPELQDQKKPRNRRHHPPDT----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88632-1", "uniprot_id": "SEM3F_MOUSE", "id": "O88632-1", "name": "Semaphorin-3F", "aln": "----------------------------------------------------MLVTAFILWASLLTGAWPATPIQDQLPATPRVRLSFKELKATGTAHFFNFLLNTTD-------YRILLKDEDHDRMYVGSKDYVLSLDLHDIN-----REPLIIHWAASPQRIEECILSGKDGNGECGNFVRLIQPWNRT-HLYVCGTGAYNPMCTYVNRGRRAQALPWTQMQVVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALINEE-------LYAGVYIDFMGTDAAIFRTLG--------KQTAMRTDQYNSRWLNDPSFIHAELIPDSAER---NDDKLYFFFRERSAEAP------QNPA-VYARIGRICLNDDGG-HCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDV--RNPVIYAVFT--SSGSVFRGSAVCVYSMADIRMVFNG-----PFAHKEGPNYQWMPFSGK-MPYPRPGTCPGGTFTP---SMKSTKDYPDEVINFMRTHPLMYQAVYPLQRRPLVVRTGAPYRLTTVAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQE---VEELMLEEVEVFKEP----------APVKTMTISSKRQ--QLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSK----RRSRRQDVRHGNPIRQCR---------------------------------------------------------------------------GFNSN---ANKN-AVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPSDRRREIRAEDRFLRTEQGLLLRALQLGDRGLYSCTATEN----NFKHIVTRVQLHVLGR-------------------------DAVHAALFPP--------LAVSVPPPPGTGP-----------------------------------------------------------------------PTPPYQELAQLLAQPEVG--------------------------------------------------LIHQYCQGYWRHVP-------PRPREAPGAL-------------------------------------------------------------------------------------RPPELQDQKKPRNRRHHPPDT----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13275-1", "uniprot_id": "SEM3F_HUMAN", "id": "Q13275-1", "name": "Semaphorin-3F", "aln": "----------------------------------------------------MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTD-------YRILLKDEDHDRMYVGSKDYVLSLDLHDIN-----REPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRT-HLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTASALINEE-------LYAGVYIDFMGTDAAIFRTLG--------KQTAMRTDQYNSRWLNDPSFIHAELIPDSAER---NDDKLYFFFRERSAEAP------QSPA-VYARIGRICLNDDGG-HCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDV--RNPVIYAVFT--SSGSVFRGSAVCVYSMADIRMVFNG-----PFAHKEGPNYQWMPFSGK-MPYPRPGTCPGGTFTP---SMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQE---LEELMLEEVEVFKDP----------APVKTMTISSKRQ--QLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSK----RRSRRQDVRHGNPIRQCR---------------------------------------------------------------------------GFNSN---ANKN-AVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATEN----NFKHVVTRVQLHVLGR-------------------------DAVHAALFPP--------LSMSAPPPPGAGP-----------------------------------------------------------------------PTPPYQELAQLLAQPEVG--------------------------------------------------LIHQYCQGYWRHVP-------PSPREAPGAP-------------------------------------------------------------------------------------RSPEPQDQKKPRNRRHHPPDT----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U4S8-1", "uniprot_id": "A0AB32U4S8_DANRE", "id": "A0AB32U4S8-1", "name": "", "aln": "----------------------------------------------------MLLDSLWPVQVLLVLSVLTLVLGNEPQNAPRVFLSFKDLRSTGTAHYFSFLLNTSD-------YRILRMDEDHDRMYVGSKDYILSLDLHDIN-----REPLIIHWPVSPQRKTECVLSGKDTNGECGNFIRLIEPWNRT-HLYICGTGAYNPVCTYVNRGRKPMTAMHLQMPQTRGRASRAAEPETVFDETG-LQEYVFHLEPGKEDSGKGKCPYDPKLNSVSALINGE-------LYAGVYIDFMGTDSAIFRTLG--------KNAVMRTDQYNSRWLNDPSFVHVHLIPDSGEK---NDDKLYFFFREKSSEMG------QSPK-SQSRIGRICLNDDGG-HCCLVNKWSTFLKARLICSVPGADGIETHFDELRDVYIQPTQDT--KNPVIYGVFS--VSGSVFKGSAVCVYSMADIRMVFNG-----PFAHKEGPNYQWVAYTGK-IPYPRPGTCPGGTFTP---NMKSTKDYPDEVINFMRNHPTMYNSVYPVHKRPLVVRTNVDYEFTTITVDQVTAADGNYEVLFLGTDKGTVQKVIVLPSDDLQ---TEELVLEEVEVFKVP----------TSITTMKISSKRQ--QLYVASAVGVTHMALHRCDVYGEACADCCLARDPYCAWDGKSCSRYSASQKRLPFRRSRRQDVKYGNPIRQCR---------------------------------------------------------------------------GYNSN---INKN-TLETVQYGVEGSSTFLECQARSPHAAIKWHLHRDNSDRRREVRSDGRVLKTDQGLLLRSLQSSDSGIYICTATEK----NFKHTLVKLQLLVLTN-------------------------QAVNNILVDTGR------PVVSPLQSSAWTP-----------------------------------------------------------------------SAGQYKDLLTILSQPEMG--------------------------------------------------LINQYCQDYWQYGD-------PLTG-VIKAK-------------------------------------------------------------------------------------DLKELKEQKKPRNRRHHGDEEET--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1MAG8-1", "uniprot_id": "F1MAG8_RAT", "id": "F1MAG8-1", "name": "", "aln": "---------------------------------------MNANKDENPRPRSQDLHLFHAGMMLIVTVLYLPVTETSKQNIPRLKLTYKDLLLSNTCIPFLGSSEGLD-------FQTLLLDEERGILLLGAKDHVFLLNLVDLN-----KNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKT-HVYVCGTGAFHPLCGYIDLGANK-------------------------------EELIFKLDMQNLESGRLKCPFDPQQPFASVMTDEH-------LYSGTASDFLGKDTAFTRSLGL-----MQDHHYIRTDISEHYWLNGAKFIGTFPIPDTYNP---DDDKIYFFFRESSQEGS------TSDRSILSRVGRVCKNDVGG-QRSLINKWTTFLKARLVCSIPGSDGADTHFDELQDIYLLPTRDE--RNPVVYGVFT--TTSSIFKGSAVCVYSMADIRAVFNG-----PYAHKESADHRWVQYDGR-IPYPRPGTCPSKTYDP---LIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWN---MEEVVLEELQVFKHP----------TAILNMELSLKQQ--QLYVGSWDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPT----SKRRARRQDVKYGDPITQCW---------------------------------------------------------------------------DIEDSISHEAAD---EKVIFGIEFNSTFLECIPKSQQASVEWYIQRSGDEHREELKPDERIIKTDYGLLIRSLQKKDSGIYYCKAQEH----TFIHTIVKLTLNVIEN-------------------------EQMENNQRAEYQ------EGQVKDLLAES--------------------------------------------------------------------------RLRYKDYIQILSSPN---------------------------------------------------FSLDQYCEQMWYRE--------KRRQRNKG-------------------------------------------------------------------------------------SAKWKHMQEMKKKRNRRHHRDLDELQRSVAT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH34-1", "uniprot_id": "SEM3D_MOUSE", "id": "Q8BH34-1", "name": "Semaphorin-3D", "aln": "---------------------------------------MNVTKDENPRSRSQDLHLFHAWMMLIMTVLFLPVTETSKQNIPRLKLTYKDLLLSNTCIPFLGSSEGLD-------FQTLLLDEERGILLLGAKDHVFLLSLVDLN-----KNFKKIYWPAAKERVELCKLAGKDANAECANFIRVLQPYNKT-HVYVCGTGAFHPLCGYIDLGANK-------------------------------EELIFKLDTHNLESGRLKCPFDPQQPFASVMTDEH-------LYSGTASDFLGKDTAFTRSLGL-----MQDHHSIRTDISEHHWLNGAKFIGTFPIPDTYNP---DDDKIYFFFRESSQEGS------TSDRSILSRVGRVCKNDVGG-QRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTRDE--RNPVVYGVFT--TTSSIFKGSAVCVYSMADIRAVFNG-----PYAHKESADHRWVQYDGR-IPYPRPGTCPSKTYDP---LIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWN---MEEVVLEELQVFKHP----------TAILNMELSLKQQ--QLYVGSWDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPT----SKRRARRQDVKYGDPITQCW---------------------------------------------------------------------------DIEDSISHETAD---EKVIFGIEFNSTFLECIPKSQQASVEWYIQRSGDEHREELKPDERIIKTDYGLLIRSLQKKDSGMYYCKAQEH----TFIHTIVKLTLNVIEN-------------------------EQMENTQRAEYQ------EGQVKDLLAES--------------------------------------------------------------------------RLRYKDYIQILSSPN---------------------------------------------------FSLDQYCEQMWYKE--------KRRQRNKG-------------------------------------------------------------------------------------SPKWKHMQEMKKKRNRRHHRDLDELQRSVAT--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95025-1", "uniprot_id": "SEM3D_HUMAN", "id": "O95025-1", "name": "Semaphorin-3D", "aln": "---------------------------------------MNANKDERLKARSQDFHLFPALMMLSMTMLFLPVTGTLKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLD-------FQTLLLDEERGRLLLGAKDHIFLLSLVDLN-----KNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKT-HIYVCGTGAFHPICGYIDLGVYK-------------------------------EDIIFKLDTHNLESGRLKCPFDPQQPFASVMTDEY-------LYSGTASDFLGKDTAFTRSLGP-----THDHHYIRTDISEHYWLNGAKFIGTFFIPDTYNP---DDDKIYFFFRESSQEGS------TSDKTILSRVGRVCKNDVGG-QRSLINKWTTFLKARLICSIPGSDGADTYFDELQDIYLLPTRDE--RNPVVYGVFT--TTSSIFKGSAVCVYSMADIRAVFNG-----PYAHKESADHRWVQYDGR-IPYPRPGTCPSKTYDP---LIKSTRDFPDDVISFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVLKVVSISKEKWN---MEEVVLEELQIFKHS----------SIILNMELSLKQQ--QLYIGSRDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPT----SKRRARRQDVKYGDPITQCW---------------------------------------------------------------------------DIEDSISHETAD---EKVIFGIEFNSTFLECIPKSQQATIKWYIQRSGDEHREELKPDERIIKTEYGLLIRSLQKKDSGMYYCKAQEH----TFIHTIVKLTLNVIEN-------------------------EQMENTQRAEHE------EGKVKDLLAES--------------------------------------------------------------------------RLRYKDYIQILSSPN---------------------------------------------------FSLDQYCEQMWHRE--------KRRQRNKG-------------------------------------------------------------------------------------GPKWKHMQEMKKKRNRRHHRDLDELPRAVAT--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63548-1", "uniprot_id": "SEM3A_RAT", "id": "Q63548-1", "name": "Semaphorin-3A", "aln": "---------------------------------------------------MGWFTGIACLFWGILLTARANYAN-GKNNVPRLKLSYKEMLESNNVITFNGLANSSS-------YHTFLLDEERSRLYVGAKDHIFSFNLVNI------KDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQT-HLYACGTGAFHPICTYIEVGHHP-------------------------------EDNIFKLQDSHFENGRGKSPYDPKLLTASLLIDGE-------LYSGTAADFMGRDFAIFRTLG--------HHHPIRTEQHDSRWLNDPRFISAHLIPESDNP---EDDKVYFFFRENAIDGE------HSGKATHARIGQICKNDFGG-HRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNSKDP--KNPIVYGVFT--TSSNIFKGSAVCMYSMSDVRRVFLG-----PYAHRDGPNYQWVPYQGR-VPYPRPGTCPSKTFG----GFDSTKDLPDDVITFARSHPAMYNPVFPINNRPIMIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSVPKETWHD--LEEVLLEEMTVFREP----------TTISAMELSTKQQ--QLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSSCSRYFPT----AKRRTRRQDIRNGDPLTHCS---------------------------------------------------------------------------DLQHHDNHHGHS-LEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEDRKEEIRVGDHIIRTEQGLLLRSLQKKDSGNYLCHAVEH----GFMQTLLKVTLEVIDT-------------------------EHLEELLHKDDDGDGSKTKEMSSSMTPSQ--------------------------------------------------------------------------KVWYRDFMQLINHPNL--------------------------------------------------NTMDEFCEQVWKRD--------RKQRRQRP-------------------------------------------------------------------------------GHSQGSSNKWKHMQESKKGRNRRTH-EFERAPRSV----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08665-1", "uniprot_id": "SEM3A_MOUSE", "id": "O08665-1", "name": "Semaphorin-3A", "aln": "---------------------------------------------------MGWFTGIACLFWGVLLTARANYAN-GKNNVPRLKLSYKEMLESNNVITFNGLANSSS-------YHTFLLDEERSRLYVGAKDHIFSFNLVNI------KDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLEAYNQT-HLYACGTGAFHPICTYIEVGHHP-------------------------------EDNIFKLQDSHFENGRGKSPYDPKLLTASLLIDGE-------LYSGTAADFMGRDFAIFRTLG--------HHHPIRTEQHDSRWLNDPRFISAHLIPESDNP---EDDKVYFFFRENAIDGE------HSGKATHARIGQICKNDFGG-HRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNSKDP--KNPIVYGVFT--TSSNIFKGSAVCMYSMSDVRRVFLG-----PYAHRDGPNYQWVPYQGR-VPYPRPGTCPSKTFG----GFDSTKDLPDDVITFARSHPAMYNPVFPINNRPIMIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSVPKETWHD--LEEILLEEMTVFREP----------TTISAMELSTKQQ--QLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSSCSRYFPT----AKRRTRRQDIRNGDPLTHCS---------------------------------------------------------------------------DLQHHDNHHGPS-LEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEDRKEEIRMGDHIIRTEQGLLLRSLQKKDSGNYLCHAVEH----GFMQTLLKVTLEVIDT-------------------------EHLEELLHKDDDGDGSKIKEMSSSMTPSQ--------------------------------------------------------------------------KVWYRDFMQLINHPNL--------------------------------------------------NTMDEFCEQVWKRD--------RKQRRQRP-------------------------------------------------------------------------------GHSQGSSNKWKHMQESKKGRNRRTH-EFERAPRSV----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14563-1", "uniprot_id": "SEM3A_HUMAN", "id": "Q14563-1", "name": "Semaphorin-3A", "aln": "---------------------------------------------------MGWLTRIVCLFWGVLLTARANYQN-GKNNVPRLKLSYKEMLESNNVITFNGLANSSS-------YHTFLLDEERSRLYVGAKDHIFSFDLVNI------KDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQT-HLYACGTGAFHPICTYIEIGHHP-------------------------------EDNIFKLENSHFENGRGKSPYDPKLLTASLLIDGE-------LYSGTAADFMGRDFAIFRTLG--------HHHPIRTEQHDSRWLNDPKFISAHLISESDNP---EDDKVYFFFRENAIDGE------HSGKATHARIGQICKNDFGG-HRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDP--KNPVVYGVFT--TSSNIFKGSAVCMYSMSDVRRVFLG-----PYAHRDGPNYQWVPYQGR-VPYPRPGTCPSKTFG----GFDSTKDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYD--LEEVLLEEMTVFREP----------TAISAMELSTKQQ--QLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSACSRYFPT----AKRRTRRQDIRNGDPLTHCS---------------------------------------------------------------------------DL-HHDNHHGHS-PEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEERKEEIRVDDHIIRTDQGLLLRSLQQKDSGNYLCHAVEH----GFIQTLLKVTLEVIDT-------------------------EHLEELLHKDDDGDGSKTKEMSNSMTPSQ--------------------------------------------------------------------------KVWYRDFMQLINHPNL--------------------------------------------------NTMDEFCEQVWKRD--------RKQRRQRP-------------------------------------------------------------------------------GHTPGNSNKWKHLQENKKGRNRRTH-EFERAPRSV----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W686-1", "uniprot_id": "SE3AB_DANRE", "id": "Q9W686-1", "name": "Semaphorin-3ab", "aln": "---------------------------------------------------MDYLWWIVLLIWTLIAPERGTVAQRSKSNVPRLKPSYKEMLESNNLLTFNGLANSSA-------YHTFLLDEERGRLFVGAKDHVLSFNLVDIN-----MDQQLISWPSSPSRRDECKWAGKDVQKECANFIKVLQPFNQT-HLYACGTGAFHPVCAHVEVGKRS-------------------------------EDNTFRLG-SSFENGRGKSPYDPKLQTASMLIDGE-------LYAGTSADFMGRDFAIFRTLG--------KHHPIRTEQHDSRWLNDPRFVSVHLIPESDNA---EDDKIYLFFRENAIDGE------QISKATHARIGQLCKNDFGG-HRSLVNKWTTFLKARLVCSVPGLNGIDTHFDELQDVFLMSSKDP--KNPIIYAVFT--TSSNIFKGSAVCMYSMADIRRVFLG-----PYAHRDGPNYQWVPFLNR-VPYPRPGTCPSKTFD----GFESTKDFPDDVITFARSHPAMYNPVFPINNHPIIIKTDVDYQFTQIVVDRVEAEDGQYDVMFIGTDMGTVLKVVSIPRGTWHD--LEEVLLEEMTVFREP----------TAITAMELSTKQQ--QLYLGSAIGVSQMPLHRCDVYGKACAECCLARDPYCAWDGSQCSRYFPT----AKRRTRRQDIRNGDPLTQCS---------------------------------------------------------------------------DLQHHDEADGEAGLLDKTVYGVENSSSFLECSPKSQRALIYWQFQRHGEDHKLEIKSDERVLGTEQGLLIRSLHQKDSGVYYCHAVEH----GFIQTLLRLTLNVIPA-------------------------EHLDDLLHRDPP---------DTNDPANG--------------------------------------------------------------------------KMWYRDFLSLINPPSP--------------------------------------------------NSVDQLCEQVWKRE--------RKQRRQKANLLHASQSH------------------------------------------------------------------TSQILHSSQSHAKWKLLQENKKGRNRRTH-EMQRAPRSV----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZHJ3-1", "uniprot_id": "D3ZHJ3_RAT", "id": "D3ZHJ3-1", "name": "Semaphorin-3B", "aln": "-----------------------------------------------------MGRAEAAAMIPGLALLWVAGLGDAAPNLPRLRLSFQELQAQHGIRTFR-LERTCC-------YEALLVDEERGRLFVGAENHVASLSLDNIS-----KRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNHT-HLLACGTGAFHPTCAFVEVGHRL-------------------------------EEPMLRLDLRKLEDGKGKSPYDPRHRAASVLVGEE-------LYSGVAADLMGRDFTIFRSLG--------QNPSLRTEPHDSRWLNEPKFVKVFWIPESENP---DDDKIYFFFRESAVEAAP-----AMGRMTVSRVGQICRNDLGG-QRSLVNKWTTFLKARLVCSVPGVEG-DTHFDQLQDVFLLSSRDR--QTPFLYAVFS--TSSGIFQGSAVCVYSMNDVRRAFLG-----PFAHKEGPTHQWVSYQGR-VPYPRPGMCPSKTFG----TFSSTKDFPDDVIQFARNHPLMYNSVLPMGGRPLFLQVGAGYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPN--SEGLLLEELQVFEDS----------AAITSMQISSKRH--QLYIASPSAVAQIALHRCPALGRACAECCLARDPYCAWDGSACTRFQPT----AKRRFRRQDIRNGNPSTLCS---------------------------------------------------------------------------GDPSHSV------LLERKVLGVERGSAFLECEPRSLQAHVEWTFHRAGEAAHTQVLAEERVERTARGLLLRGLRRQDSGVYLCVAVEQ----GFSQPLRRLVLHVLSA-------------------------AQAERLARAEEA---------AVPAPPGP--------------------------------------------------------------------------KLWYRDFLQLVEPGGG-----------------------------------------------GGANSLR-MCRPQPGPH--------SVAADSR------------------------------------------------------------------------------------------------RKGRNRRMHVSELRAERGPRSAAHW----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62177-1", "uniprot_id": "SEM3B_MOUSE", "id": "Q62177-1", "name": "Semaphorin-3B", "aln": "-----------------------------------------------------MGRAEAAAMIPGLALLWVAGLGDTAPNLPRLRLSFQELQARHGVRTFR-LERTCC-------YEALLVDEERGRLFVGAENHVASLSLDNIS-----KRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHTYNHT-HLLACGTGAFHPTCALWRWAT-A-------------------------------GGTHASTGPEKLEDGKGKTPYDPRHRAASVLVGEE-------LYSGVTADLMGRDFTIFRSLG--------QNPSLRTEPHDSRWLNEPKFVKVFWIPESENP---DDDKIYFFFRESAVEAAP-----AMGRMSVSRVGQICRNDLGG-QRSLVNKWTTFLKARLVCSVPGVEG-DTHFDQLQDVFLLSSRDR--QTPLLYAVFS--TSSGVFQGSAVCVYSMNDVRRAFLG-----PFAHKEGPTHQWVSYQGR-VPYPRPGMCPSKTFG----TFSSTKDFPDDVIQFARNHPLMYNPVLPMGGRPLFLQVGAGYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPN--SEGLLLEELQVFEDS----------AAITSMQISSKRQ--QLYIASRSAVAQIALHRCTALGRACAECCLARDPYCAWDGSACTRFQPT----AKRRFRRQDIRNGDPSTLCS---------------------------------------------------------------------------GDSSHSV------LLEKKVLGVESGSAFLECEPRSLQAHVQWTFQGAGEAAHTQVLAEERVERTARGLLLRGLRRQDSGVYLCVAVEQ----GFSQPLRRLVLHVLSA-------------------------AQAERLARAEEA---------AAPAPPGP--------------------------------------------------------------------------KLWYRDFLQLVEPGGG-----------------------------------------------GGANSLR-MCRPQPGHH--------SVAADSR------------------------------------------------------------------------------------------------RKGRNRRMHVSELRAERGPRSAAHW----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13214-1", "uniprot_id": "SEM3B_HUMAN", "id": "Q13214-1", "name": "Semaphorin-3B", "aln": "-----------------------------------------------------MGRAGAAAVIPGLALLWAVGLGSAAPSPPRLRLSFQELQAWHGLQTFS-LERTCC-------YQALLVDEERGRLFVGAENHVASLNLDNIS-----KRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRT-HLLACGTGAFHPTCAFVEVGHRA-------------------------------EEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEE-------LYSGVAADLMGRDFTIFRSLG--------QRPSLRTEPHDSRWLNEPKFVKVFWIPESENP---DDDKIYFFFRETAVEAAP-----ALGRLSVSRVGQICRNDVGG-QRSLVNKWTTFLKARLVCSVPGVEG-DTHFDQLQDVFLLSSRDH--RTPLLYAVFS--TSSSIFQGSAVCVYSMNDVRRAFLG-----PFAHKEGPMHQWVSYQGR-VPYPRPGMCPSKTFG----TFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPS--AEGLLLEELHVFEDS----------AAVTSMQISSKRH--QLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPS----AKRRFRRQDVRNGDPSTLCS---------------------------------------------------------------------------GDSSRPA------LLEHKVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQ----GFTQPLRRLSLHVLSA-------------------------TQAERLARAEEA---------APAAPPGP--------------------------------------------------------------------------KLWYRDFLQLVEPGGG-----------------------------------------------GSANSLR-MCRPQPALQ--------SLPLESR------------------------------------------------------------------------------------------------RKGRNRRTHAPEPRAERGPRSATHW----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NJX9-1", "uniprot_id": "A0A8M1NJX9_DANRE", "id": "A0A8M1NJX9-1", "name": "Semaphorin-3B", "aln": "-----------------------------------------------------MMMMMCCTLVLFGLIGISASLSGSSQSSPRMKLSYKDLQQFNGIKRFD-LERSCS-------FGALLLDEERGRLFVGARNFLLSLSLDNIS-----KQEQKIYWPAPVDWREECNWAGKDINTDCVNYVKVLHHYNRT-HLYACGTGAFHPTCAYVEVGQKM-------------------------------EDHVFRIDPSLVEDGKGKSPYDPRHTSASVLIGDE-------LYAGVATDLMGRDFTIFRSMG--------QKPSIRTEQHDSRWLNEPKFIAAFGVPESDNP---DDDKVFFFFRETAVEAQ------GFGKVTYSRIGQLCRNDMGG-QRSLVNKWTTFLKARLVCSVPGNDGTETHFDELRDVFLLQTRDK--KNPLIYTVFT--TSSSVFQGSAVCLYTMNDIRRAFLG-----PFAHKEGPNYQWIPFQGK-VPYPRPGMCPSKTFG----SFESTKGFPDNVIQFARHHPLMFNPVTPLGGRPLFLRTGIPYTFTQITVDRVNAADGHYDVMFIGTDVGSVLKVISVPKGSWSN--TE-LLLEELHVFKDS----------SSIISMQISSKRQ--QLYVGSDTGVVQVPLHRCSMYGKACAECCLARDPYCAWDGHTCTRYLPN----TKRRFRRQDVRNGDPNALCS---------------------------------------------------------------------------GDHQKQR------VLEKRLYAVDGSSSFLECVPKSLQAQITWTYQKLPENPREEVRLDERVLQTERGLLLRRAVRRDAGVYQCHSMEH----GFTQTILAITLEILPS-------------------------AGSAPSAVNPRS---------PAHSHVSHGQST--------------------------------------------------------------------NQKLWYRDFMQLVDHPNLNT------------------------------------VDQICEQVWSRKHSLSGKSPPDPAIE--------VPAHDPLN-------------------------------------------------------------------------------------SKKWKHLKEMRKGRNRRTHDGKP-ASRAPRSAGE-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O15041-1", "uniprot_id": "SEM3E_HUMAN", "id": "O15041-1", "name": "Semaphorin-3E", "aln": "---------------------------------------------------MASAGHIITLLLWGYLLELWTGGHTADTTHPRLRLSHKELLNLNRTSIFHSPFGFLD-------LHTMLLDEYQERLFVGGRDLVYSLSLERIS-----DGYKEIHWPSTALKMEECIMKGKD-AGECANYVRVLHHYNRT-HLLTCGTGAFDPVCAFIRVGYHL-------------------------------EDPLFHLESPRSERGRGRCPFDPSSSFISTLIGSE-------LFAGLYSDYWSRDAAIFRSMG--------RLAHIRTEHDDERLLKEPKFVGSYMIPDNEDR---DDNKVYFFFTEKALEAEN------NAHAIYTRVGRLCVNDVGG-QRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDVFLLPTRDH--KNPVIFGLFN--TTSNIFRGHAICVYHMSSIRAAFNG-----PYAHKEGPEYHWSVYEGK-VPYPRPGSCASKVNG--GR-YGTTKDYPDDAIRFARSHPLMYQAIKPAHKKPILVKTDGKYNLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIYNQEMES--MEEVILEELQIFKDP----------VPIISMEISSKRQ--QLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWDGISCSRYYPTGT-HAKRRFRRQDVRHGNAAQQCF---------------------------------------------------------------------------GQQFVGDALDKT--EEHLAYGIENNSTLLECTPRSLQAKVIWFVQKGRETRKEEVKTDDRVVKMDLGLLFLRLHKSDAGTYFCQTVEH----SFVHTVRKITLEVVEE-------------------------EKVEDMFNKDDEEDRHHRMPCPAQSSISQG------------------------------------------------------------------------AKPWYKEFLQLIGYSNF--------------------------------------------------QRVEEYCEKVWCTD--------RKRKKLKM------------------------------------------------------------------------------------SPSKWKYANPQEKKLRS--KPEHYRLPRHTLDS-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NS98-1", "uniprot_id": "SEM3G_HUMAN", "id": "Q9NS98-1", "name": "Semaphorin-3G", "aln": "---------------------------------------------------MAPSAWAICWLLGGLLLHGGSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLN-------LQAMYLDEYRDRLFLGGLDALYSLRLDQAW-----PDPREVLWPPQPGQREECVRKGRDPLTECANFVRVLQPHNRT-HLLACGTGAFQPTCALITVG-HR-------------------------------GEHVLHLEPGSVESGRGRCPHEPSRPFASTFIDGE-------LYTGLTADFLGREAMIFRSGG--------PRPALRSDSD-QSLLHDPRFVMAARIPENSDQ---DNDKVYFFFSETVPSPDG-----GSNHVTVSRVGRVCVNDAGG-QRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAG--KSLEVYALFS--TVSAVFQGFAVCVYHMADIWEVFNG-----PFAHRDGPQHQWGPYGGK-VPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQAGGSAE--PEEVVLEELQVFKVP----------TPITEMEISVKRQ--MLYVGSRLGVAQLRLHQCETYGTACAECCLARDPYCAWDGASCTHYRPS---LGKRRFRRQDIRHGNPALQCL---------------------------------------------------------------------------GQSQEEEAVGLV--AATMVYGTEHNSTFLECLPKSPQAAVRWLLQRPGDEGPDQVKTDERVLHTERGLLFRRLSRFDAGTYTCTTLEH----GFSQTVVRLALVVIVA-------------------------SQLDNLFPPEPKPE----EPPARGGLASTP------------------------------------------------------------------------PKAWYKDILQLIGFANL--------------------------------------------------PRVDEYCERVWCRGTTECSGCFRSRSRGKQ------------------------------------------------------------------------------------ARGKSWAGLELGKKMKSRVHAEHNRTPREVEAT-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTL3-1", "uniprot_id": "SEM6C_RAT", "id": "Q9WTL3-1", "name": "Semaphorin-6C", "aln": "-----------------------------------------------MPRAPHSMPLLLLLLLS--LPQAQTAFPQDPIPLLTSDLQGTSPSSWFRGLEDDAVAAELG-------LDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQ--DMENCAVRGKL-TDECYNYIRVLVPWDSQ-TLLACGTNSFSPVCRSYGITSLQ--------------------------------------QEGEELSGQARCPFDATQSTVAISAEGS-------LYSATAADFQASDAVVYRSLG--------PQPPLRSAKYDSKWLREPHFVYALEHG----------DHVYFFFREVSVEDA------RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDST--FYFDVLQSLTGPVNLHG---RSALFGVFT--TQTNSIPGSAVCAFYLDDIERGFEG-----KFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAA---ALFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLT-LTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVLKVLPP---GGQSLGPEPIILEEIDAYSHARCSGKRSP-RAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQRSCLASLDPYCGWHRF-RGCVNIRG---PGGTDVDLT-GNQESMEHGDCQDGATGSQSGPGDSAYVLLGPGPSPETPSSPSDAHPG--------------PQSSTLGAHT------------QGVRRDLSPASASRSIPIPLLLACVAAAFALGASVSGLLVSCACRR---ANRRRSKDIETPGLPRPLS-LRSLARLHGGGPEPPPPPKD----GDAAQTPQLYTTFLP--------------------PPEGGSPPELACLPTPETTPELPVKHLRASGGPWEWNQNGNNASE-------GPGRP---------------RGCSAAGG---------PAPRVLVRPPPPGCPGQEVEVTTLEELLRYLHGPQPPRK---------GSEPLASAPFTS-----------RPPASEPGAALFVDSSPMPRDCVPPLRLDVPPDGKRAAPSGRPALS-APAPRLG-------------VSGSRRLP----------FPTHR-APPGLLTRVPSGG------------------PSRYSGGPGRHLLYLGRPDGHRGRSLKRVDVKSP-LSPKPPLATPP--QPAPHGSHFNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTM3-1", "uniprot_id": "SEM6C_MOUSE", "id": "Q9WTM3-1", "name": "Semaphorin-6C", "aln": "-----------------------------------------------MPRAPHSMPLLLLLLLLSSLPQAQAAFPQDPTPLLTSDLQGASPSSWFRGLEDDAVAAELG-------LDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQ--DMENCAVRGKL-TDECYNYIRVLVPWNSQ-TLLACGTNSFSPMCRSYGITSLQ--------------------------------------QEGEELSGQARCPFDATQSTVAIFAEGS-------LYSATAADFQASDAVVYRSLG--------PQPPLRSAKYDSKWLREPHFVYALEHG----------EHVYFFFREVSVEDA------RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDST--FYFDVLQSLTGPVNLHG---RSALFGVFT--TQTNSIPGSAVCAFYLDDIERGFEG-----KFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAA---ASFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLT-LTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVLKVLPP---GGQSLGSEPIVLEEIDAYSHARCSGKRSP-RAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQRSCLASLDPYCGWHRS-RGCMSIRG---PGGTDVDLT-GNQESTEHGDCQDGATGSQSGPGDSAY----------------------------------------------------------GVRRDLSPASASRSIPIPLLLACVAAAFALGASVSGLLVSCACRR---ANRRRSKDIETPGLPRPLS-LRSLARLHGGGPEPPPPPKD----GDAAQTPQLYTTFLP--------------------PPDGGSPPELACLPTPETTPELPVKHLRASGGPWEWNQNGNNASE-------GPGRPP--------------RGCSGAGG---------PAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRK---------GSEPLASAPFTS-----------RPPASEPGASLFVDSSPMPRDGVPPLRLDVPPEGKRAAPSGRPALS-APAPRLG-------------VGGSRRLP----------FPTHR-APPGLLTRVPSGG------------------PARYSGGPGRHLLYLGRPEGHRGRSLKRVDVKSP-LSPKPPLASPP--QPAPHGGHFNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3T2-1", "uniprot_id": "SEM6C_HUMAN", "id": "Q9H3T2-1", "name": "Semaphorin-6C", "aln": "-----------------------------------------------MPRAPHFMPLLLLLLLLS-LPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELG-------LDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGKL-TDECYNYIRVLVPWDSQ-TLLACGTNSFSPVCRSYGITSLQ--------------------------------------QEGEELSGQARCPFDATQSNVAIFAEGS-------LYSATAADFQASDAVVYRSLG--------PQPPLRSAKYDSKWLREPHFVQALEHG----------DHVYFFFREVSVEDA------RLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDST--FYFDVLQALTGPVNLHG---RSALFGVFT--TQTNSIPGSAVCAFYLDEIERGFEG-----KFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGA---ALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLT-LTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTP---GGRSGGPEPILLEEIDAYSPARCSGKRTA-QTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSS-RGCVDIRG---SGGTDVDQA-GNQESMEHGDCQDGATGSQSGPGDSAY----------------------------------------------------------GVRRDLPPASASRSVPIPLLLASVAAAFALGASVSGLLVSCACRR---AHRRRGKDIETPGLPRPLS-LRSLARLHGGGPEPPPPSKD----GDAVQTPQLYTTFLP--------------------PPEGVPPPELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKE-------GPGRS---------------RGGHAAGG---------PAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRK---------GAEP--PAPLTS-----------RALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALS-APAPRLG-------------VGGGRRLP----------FSGHR-APPALLTRVPSGG------------------PSRYSGGPGKHLLYLGRPEGYRGRALKRVDVEKPQLSLKPPLVGPSSRQAVPNGGRFNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HGM6-1", "uniprot_id": "A0AC58HGM6_DANRE", "id": "A0AC58HGM6-1", "name": "", "aln": "MAAERAAWRNGLSGLICTTTLRWSSVYSGSCCVAEFYAVAEMRLVILGSRPLLALTLMLTLTCLKHLCHGATPFPQDLEPIRTVGSEHTYLYPSFQGNMSDNDTARLG-------LDFQRMLRINHMVYIAARDHVFAINLSASLER--IVPQQKLTWKTK--DVEKCTVRGKN-SDECYNYIKVLVPRNDE-TLFACGTNAFNPTCRNYKMSSLE--------------------------------------QDGEEVIGQARCPFESRQSNVGLFAGGD-------FYSATMTDFLASDAVIYRSLGE-------SSPVLRTVKYDSKWLREPHFLHAIEYG----------NYVYFFLSEIAVEYT------TLGKVVFSRVARVCKNDNGGSPRVLERYWTSFLKARLNCSVPGDSF--FYFDVLQSLTNVMQINH---RPAVLGVFT--TQANSITGSAVCAFYMDDIEKVFNG-----KFKEQRNSESAWTPVPDEAVPKPRPGSCAGDGPA---AGYKSSTNFPDETLTFIKSYPLMDEAVPSVNNRPCFTRTTSRFKLTQIAVDTAAGPYKNYTVVFLGSENGHVLKVLAS---MHPNSSYSTQVLEDIDVYNPNKCNVRG----EDRRILGLELDKDHHALFVAFTGCVIRVPLSRCSDYGICRKSCLSSRDPYCIWLSA-GNCATVAPGFKSGFEQYVES-GYPQYPDSCHDVLATTRKQNPAVDSAYGKTSPTSASTTNQGPAGAPETGTHPEEGRRGGQGSPDLEPGSVEM------------EGVRRPPEVDKSNHSVHYTLLIACVLVAFVLGAFLSGFLVSCYCNHNVNKTKRLSKDPEAP-IPHALS-LRSLAKLNG--LLESQNKDE----KLEVSSPKLYNSFFANGKEQAHRRNAHHAAMTELIHPHHHHSAELSGLPTPDSTPELPIKSMKAFKNQWEKNQNCNNAKEPKSH-NMGASRPTSAMQHQMFPFSHGLTNGQVLGGSVHMDERKVHNTERVVSQPYHCYPHKIVDVTSLDELLKHIHEINVATG---------KSPSVLTSSMSANAGQMAFANRVQPHIPETESAPYYSSSTLPRDSLT-RRMDIPPEIPPHHQSTLERVSRHPAQRHS-------------LITTPKMPSGGVVPRQHSFNQRSSHQPLLLSRMNSNGSNS---------GCDVRHPLIPNGYLTRQHSYSEQPEVHRGAIVRRTASLKPDVPPKPLFIPAS--SPVNQAGKFNY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZAG0-1", "uniprot_id": "D3ZAG0_RAT", "id": "D3ZAG0-1", "name": "Semaphorin-6A", "aln": "------------------------------------------------------MRPAALLLCLTLLRCAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQR------HRLDIQMIMIMNRTLYIAARDHIYTVDIDTSHTEE-IYCSKKLTWKSRQADVDTCRMKGKH-KDECHNFIKVLLKKNDD-TLFVCGTNAFNPSCRNYRVDTLE--------------------------------------TFGDEFSGMARCPYDAKHANIALFADGK-------LYSATVTDFLAIDAVIYRSLG--------DSPTLRTVKHDSKWLKEPYFVQAVDYG----------DYIYFFFREIAVEYN------TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSH--FYFNILQAVTDVIRING---RDVVLATFS--TPYNSIPGSAVCAYDMLDIANVFTG-----RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSL---EKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNTAGPYENHTVVFLGSEKGIILKFLAR--IGSSGFLNGSLFLEEMNVYNPEKCSYDG---VEDKRIMGMQLDKASGSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWVKETGSCAHLSP-LSRLAFEQDIERGNTDGLGDCHNSFVALNGRASSLYPSTTTSDSASRDGHESQGGMLDWNDLLKAPGNTDPLGAVSSHNHQDK-------------KGVIRESYLKSNDQLVPVTLLAIAVILAFVMGAVFSGIIVYCVCDHR-RKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDSQS---------KDPKPEAILTPLMHNGK------LATPSNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPNRGSR---EWERN-----------QNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLP---ITQQGYQHEYVDQPKMSEVVAQMALEDQAATL------------EYKTIKEHLSS-------------KSPNHGVNLVENLDSLPPKVPQREASLGPTGASLSQTGLSKRLEMQHSSSYG------LEYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSLGRGDNPPPAPQRVDSIQVHSPQPSGQAVTVSRQPSLNAYNSLTRSG-LKRTPSLKPDVPPKPS-FAPLS-TSMKPNDACT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35464-1", "uniprot_id": "SEM6A_MOUSE", "id": "O35464-1", "name": "Semaphorin-6A", "aln": "------------------------------------------------------MRPAALLLCLTLLHCAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQR------HRLDIQMIMIMNRTLYVAARDHIYTVDIDTSHTEE-IYCSKKLTWKSRQADVDTCRMKGKH-KDECHNFIKVLLKKNDD-TLFVCGTNAFNPSCRNYRVDTLE--------------------------------------TFGDEFSGMARCPYDAKHANIALFADGK-------LYSATVTDFLAIDAVIYRSLG--------DSPTLRTVKHDSKWLKEPYFVQAVDYG----------DYIYFFFREIAVEYN------TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSH--FYFNILQAVTDVIRING---RDVVLATFS--TPYNSIPGSAVCAYDMLDIANVFTG-----RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSL---EKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNAAGPYQNHTVVFLGSEKGIILKFLAR--IGSSGFLNGSLFLEEMNVYNPEKCSYDG---VEDKRIMGMQLDRASGSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWVRESGSCAHLSP-LSRLTFEQDIERGNTDGLGDCHNSFVALNGHASSLYPSTTTSDSASRDGYESRGGMLDWNDLLEAPGSTDPLGAVSSHNHQDK-------------KGVIRESYLKSNDQLVPVTLLAIAVILAFVMGAVFSGIIVYCVCDHR-RKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQS---------KDPKPEAILTPLMHNGK------LATPSNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPNRGSR---EWERN-----------QNIINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLP---ITQQGYQHEYVDQPKMSEVVAQMALEDQAATL------------EYKTIKEHLSS-------------KSPNHGVNLVENLDSLPPKVPQREASLGPPGTSLSQTGLSKRLEMQHSSSYG------LEYKRSYPTNSLTRSHQTTTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSG-LKRTPSLKPDVPPKPS-FAPLS-TSMKPNDACT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2E6-1", "uniprot_id": "SEM6A_HUMAN", "id": "Q9H2E6-1", "name": "Semaphorin-6A", "aln": "------------------------------------------------------MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQR------HRLDIQMIMIMNGTLYIAARDHIYTVDIDTSHTEE-IYCSKKLTWKSRQADVDTCRMKGKH-KDECHNFIKVLLKKNDD-ALFVCGTNAFNPSCRNYKMDTLE--------------------------------------PFGDEFSGMARCPYDAKHANVALFADGK-------LYSATVTDFLAIDAVIYRSLG--------ESPTLRTVKHDSKWLKEPYFVQAVDYG----------DYIYFFFREIAVEYN------TMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSH--FYFNILQAVTDVIRING---RDVVLATFS--TPYNSIPGSAVCAYDMLDIASVFTG-----RFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSL---ERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLAR--IGNSGFLNDSLFLEEMSVYNSEKCSYDG---VEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLSP-NSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGMLDWKHLLDSPDSTDPLGAVSSHNHQDK-------------KGVIRESYLKGHDQLVPVTLLAIAVILAFVMGAVFSGITVYCVCDHR-RKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQS---------KDPKPEAILTPLMHNGK------LATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSR---EWERN-----------QNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLP---ITQQGYQHEYVDQPKMSEV-AQMALEDQAATL------------EYKTIKEHLSS-------------KSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSYG------VDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSG-LKRTPSLKPDVPPKPS-FAPLS-TSMKPNDACT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H3T3-1", "uniprot_id": "SEM6B_HUMAN", "id": "Q9H3T3-1", "name": "Semaphorin-6B", "aln": "----------------------------------------------MQTPRASPPRPAL-LLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGA----DDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTE-LRYQRKLTWRSNPSDINVCRMKGKQ-EGECRNFVKVLLLRDES-TLFVCGSNAFNPVCANYSIDTLQ--------------------------------------PVGDNISGMARCPYDPKHANVALFSDGM-------LFTATVTDFLAIDAVIYRSLG--------DRPTLRTVKHDSKWFKEPYFVHAVEWG----------SHVYFFFREIAMEFN------YLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH--FYFNVLQAVTGVVSLGG---RPVVLAVFS--TPSNSIPGSAVCAFDLTQVAAVFEG-----RFREQKSPESIWTPVPEDQVPRPRPGCCAAPG-----MQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPG-GGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD-GSCIFLSP-GTRAAFEQDVSGASTSGLGDCT---------------------------------------------------------------------------GLLRASLSEDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNG------------WAKATLLQGGPHDLDSGLLPTPEQTP-LPQKRLPTPHPH---PHALG-----------PRAWDHGHPLLPASASSSLLLLAPARAP----------------------------------------EQPPAP------------GEPTPDGRLYA-------------ARPGR-ASH-GDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPP---------------PTGSLRRPL--------GPHAPPAATLRRTHTFNSGE----------------ARPGDRHRGCHARPGTDLAHLLPYGG-ADRT------APPVP-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54951-1", "uniprot_id": "SEM6B_MOUSE", "id": "O54951-1", "name": "Semaphorin-6B", "aln": "----------------------------------------------MWTPRVPPPRPALSFFLLLLLGVTYGLFPEEPPPLSVAPRDYLSHYPVFVGSGPGRLTAAEGA----EDLNIQRVLRVNRTLFIGDRDNLYQVELEPSTSTE-LRYQRKLTWRSNPSDIDVCRMKGKQ-EGECRNFVKVLLLRDES-TLFVCGSNAFNPICANYSMDTLQ--------------------------------------LLGDSISGMARCPYDPKHANVALFSDGM-------LFTATVTDFLAIDAVIYRSLG--------DRPTLRTVKHDSKWFKEPYFVHAVEWG----------SHVYFFFREIAMEFN------YLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH--FYFNVLQAVTGVVSLGG---RPVILAVFS--TPSNSIPGSAVCAFDMNQVAAVFEG-----RFREQKSPESIWTPVPEDQVPRPRPGCCAAPG-----MQYNASSALPDEILNFVKTHPLMDEAVPSLGHSPWIVRTLMRHQLTRVAVDVGAGPWGNQTIVFLGSEAGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRPSSAGEWGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQLYSGCMKNCIGSQDPYCGWAPD-GSCIFLRP-GTSATFEQDVSGASTSGLGDCT---------------------------------------------------------------------------GLLRASLSDDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGPGGRGGAGGG-PGGPPEALLAPLMQNG------------WTKAALLHGGPHDLDTGLLPTPEQTP-LPQKRLPTPHPH---AHALG-----------SRAWDHSHALLSASASTSLLLLAPARAS----------------------------------------EQPQVP------------AEPGPESRLCA-------------PRSCR-ASHPGDFPLTPHASPDRRRVVSAPTGPLDPS-VGDGLPGPWSPP---------------ATSSLRRP---------GPHGPPTAALRRTHTFNSGE----------------ARPGG-HR-PRRHPPADSTHLLPCGT-GERT------APPVP-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZC4-1", "uniprot_id": "A0A0G2JZC4_RAT", "id": "A0A0G2JZC4-1", "name": "Semaphorin-6D", "aln": "---------------------------------------------------MRFFLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHR--------LDFQLMLKIRDTLYIAGRDQVYTVNLNDIPQTE-VIPSKKLTWRSRQQDRENCAMKGKH-KDECHNFIKVFVPRNDE-MVFVCGTNAFNPMCRYYRLSTLE--------------------------------------YDGEEISGLARCPFDARQTNVALFADGK-------LYSATVADFLASDAVIYRSMG--------DGSALRTIKYDSKWIKEPHFLHAIEYG----------NYVYFFFREIAVEHN------NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF--FYFDVLQSITDIIQING---IPTVIGVFT--TQLNSIPGSAVCAFSMDDIEKVFKG-----RFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLA---EAYKTSIDFPDDTLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAK---TSPFSLNDSVLLEEIEAYNPAKCSAES---EEDRKVVSLQLDRDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GVCERVTLGMLAGGYEQDTEYGNTAHLGDCHESLPTSTTPDYKIFGGPTSDMEVPSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTIS----GVRWEVQSGDSNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSGSFAKLNGLFDSPVKEY------QQNIDSPKLYSNLLTSRKE-----LPPNTDPKSMAMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSDKAHGHG-ASRK----EHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNVDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNAKAIMGEIHM-------------AHQTLMLDPVGPMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVP---MTSLERQRGYHKNSSQRHSISAVPK--NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTG-LKRTPSLKPDVPPKPS-FVPQT-TSVRPLNKYTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76KF0-1", "uniprot_id": "SEM6D_MOUSE", "id": "Q76KF0-1", "name": "Semaphorin-6D", "aln": "---------------------------------------------------MGFLLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHR--------LDFQLMLKIRDTLYIAGRDQVYTVNLNEIPQTE-VIPSKKLTWRSRQQDRENCAMKGKH-KDECHNFIKVFVPRNDE-MVFVCGTNAFNPMCRYYRLRTLE--------------------------------------YDGEEISGLARCPFDARQTNVALFADGK-------LYSATVADFLASDAVIYRSMG--------DGSALRTIKYDSKWIKEPHFLHAIEYG----------NYVYFFFREIAVEHN------NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF--FYFDVLQSITDIIQING---IPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKG-----RFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLA---EAYKTSIDFPDDTLAFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAK---TSPFSLNDSVLLEEIEAYNPAKCSAES---EEDRKVVSLQLDKDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GVCERVTLGMLPGGYEQDTEYGNTAHLGDCHESLPPSTTPDYKIFGGPTSDMEVSSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTISGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSGSFAKLNGLFDSPVKEY------QQNIDSPKLYSNLLTSRKE-----LPPNTDTKSMAVDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHSHG-ASRK----EHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQSMDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNPKAILGEIHM-------------AHQTLMLDPVGPMAEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVP---MTSLERQRGYHKNSSQRHSISAVPK--NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTG-LKRTPSLKPDVPPKPS-FVPQT-TSVRPLNKYTY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFY4-1", "uniprot_id": "SEM6D_HUMAN", "id": "Q8NFY4-1", "name": "Semaphorin-6D", "aln": "---------------------------------------------------MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHR--------LDFQLMLKIRDTLYIAGRDQVYTVNLNEMPKTE-VIPNKKLTWRSRQQDRENCAMKGKH-KDECHNFIKVFVPRNDE-MVFVCGTNAFNPMCRYYRLSTLE--------------------------------------YDGEEISGLARCPFDARQTNVALFADGK-------LYSATVADFLASDAVIYRSMG--------DGSALRTIKYDSKWIKEPHFLHAIEYG----------NYVYFFFREIAVEHN------NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF--FYFDVLQSITDIIQING---IPTVVGVFT--TQLNSIPGSAVCAFSMDDIEKVFKG-----RFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLA---EAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAK---TSPFSLNDSVLLEEIEAYNHAKCSAEN---EEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ-GSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSDMEVSSSSVTTMASIPEITPKVIDTWRPKLTSSRKFVVQDDPNTSDFTDPLSGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSGSFAKLNGLFDSPVKEY------QQNIDSPKLYSNLLTSRKE-----LPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHG-ASRK----ETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQM-------------AHQNLMLDPMGSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVP---MTSLERQRGYHKNSSQRHSISAMPK--NLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTG-LKRTPSLKPDVPPKPS-FVPQT-PSVRPLNKYTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLA1-1", "uniprot_id": "A0A8M2BLA1_DANRE", "id": "A0A8M2BLA1-1", "name": "", "aln": "-------------------------------------------------MGWRELTIDLLILLLVASRLDAVSFPEDNIPLDVVDRHYARQYPVFRGRPSGNESQHR--------LDFQLMTQIHDTLFIAGRDQVYLVSLRESYRNE-IIPYRKLTWRSGQADRETCAMKGKH-RDECHNFIKVLVPRNDD-LVFICGTNGFNPMCRYYRLDNLE--------------------------------------FDGEEISGLARCPFDAKQTNVALFADGK-------LYSATVADFLASDAVIYRSMG--------DGSALRTIKYDSKWLKEPHFLHAVDYG----------DFVYFFFREIAAEHN------NLGKAVYSRVARICKNDMGGSQRVLEKHWTSFVKARLNCSVPGESF--FYFDVLQAITDIIDING---VPSVVGVFT--TQLNSIPGSAVCAFSMVDIEKAFRG-----RFKEQKTPDSVWTPFPEEKLPKPRPGCCAGHGSA---ESYKTSIEFPDETLQFIKSHPLMDASVPSIGDEPWFTKTRVRYRLTALAVDNTAGPHKNYTVVFIGSEAGIVLKVLAK---TSLLSLNDSVLLEEIDVFNQAKCLSSN---EDDRRILSFHLDKDSHTLYVAFSSCVVRIPLSRCERHSSCQKSCIASRDPYCGWMSH-GACERIPATIQSG-YEQDVEYGNTAHLGDCHEFLATTSAPDFKSYGDPTSDMELPSSSVTVPATSEPIQSPQTN---PTQTP-QLFEPHGDPATSHSVEHIPGVLEGV-WEIQAGESNQMVHMNILISCVLAAFLLGAFIAGMVVYCYRDAFLRTPRKIQKDAES--AQSCTDSTGSFAKLNGLFDSPVKEY------QPNMDTPKLYTNLLSNGRE-----VPTTGETKTMLLS--GQPPELAALPTPESTPVLQQKSLQPIKNQWERAHGKMSGSRKDAPPKSPQYLPSSPPPHSAINP-HIPSAVVLPNATHENKAGFSTPEGPQAEKKVQNSEQHGSKSG-RKDQRRTVDARNTLNDLLKHLND--SNPKAIMVEMPK-------------SRQHLMLEPIVSPTEIPPKVPSREASLYSPSSSLPRNSPTKRVDVPTTPTSPTGHMGTLERQR-YHRGSSQRHSISSPPK--GLHSPSGAIVSRQPSMNRGGYIP-PTPTPPTRLDSHGVPMAMTPSVSRQSSYSGHGSLPRTS-IKRTASLKPDVPPKPNGFAPQT-AQMRPVNKYSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O75326-1", "uniprot_id": "SEM7A_HUMAN", "id": "O75326-1", "name": "Semaphorin-7A", "aln": "-------------------------------------MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQT----EPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGK-------NASVRTVNIGSTKGSCLD-----KRDCENYITLLERRSE--GLLACGTNARHPSCWNLVNGTVVP-----------------------------------------LGEMRGYAPFSPDENSLVLFEGDE-------VYSTIRKQEYNGKIPRFRRIR-----------GESELYTSDTVMQNPQFIKATIVHQDQAY----DDKIYYFFREDNPDKN------PEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNK---NFNRLQDVFLLPDPSGQWRDTRVYGVFS-----NPWNYSAVCVYSLGDIDKVFRT--------------SSLKGYHSS-LPNPRPGKCLPDQQP-----------IPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHS----FAFNIMEIQPFRRA----------AAIQTMSLDAERR--KLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE------RSVLQSINPAEPHKECP----------------------------------------------------------------------------------NPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQ-----SPNCILFIENLTAQQYGHYFCEAQEG----SYFREAQHWQLLPEDG-------------------------IMAEHLLGHACALAASLWLGVLPTLTLGLLVH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24323-1", "uniprot_id": "SEM2A_DROME", "id": "Q24323-1", "name": "Semaphorin-2A", "aln": "------------------------------------------------MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSN--CNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLP---------------------------------RSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIG----------EYVYFFFRETAVEYIN------CGKAVYSRIARVCKKDVGG-KNLLAHNWATYLKARLNCSISGEFP--FYFNEIQSVYQLPSDKS-----RFFATFT--TSTNGLIGSAVCSFHINEIQAAFNG-----KFKEQSSSNSAWLPVLNSRVPEPRPGTCVNDTSN-----------LPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYR-------NGESLSKLLDIFEVAPN--------EAIQVMEISQTRK--SLYIGTDHRIKQIDLAMCNRRYDNCFRCVR--DPYCGWDKEANTCRPYELDLLQDVANETSDICDSS-----------------------------------------------------------------------------------------VLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLGGS----LLCSYNITVDAHRCTP-------------------------PNKSNDYQKIYSDWCHEFEKYKTAMKSWE------------------------------------------------------------------------------KKQAQCSTRQNFS--------------------------------------------------SNQHPNEIFRKPNV-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : . : * * *.: .: . : **: . * .... .:: . * : . :: *: * . :.::* * ** * :::* * * . . :. . * *:* : : . **** * . . . : : : : :: : * : : : : : : : . : * * ** * * ", "identical_positions": 32, "similar_positions": 63, "identity": "2.53%" }, { "cls_id": "homologset.agr.FB:FBgn0011270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16290-1", "uniprot_id": "PGAM2_RAT", "id": "P16290-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MATHRLVMVRHGESSWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYASISKDRRYAG-LKPEELPTCESLKDTIARALPFWNEEIAPKIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNQELKPTKPMRFLGDEETVRKAMEAVAAQGKAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70250-1", "uniprot_id": "PGAM2_MOUSE", "id": "O70250-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MTTHRLVMVRHGESLWNQENRFCGWFDAELSEKGAEEAKRGATAIKDAKIEFDICYTSVLKRAIRTLWTILDVTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDTPPPPMDEKHNYYTSISKDRRYAG-LKPEELPTCESLKDTIARALPFWNEEIAPKIKAGQRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELDQNLKPTKPMRFLGDEETVRKAMEAVAAQGKAK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15259-1", "uniprot_id": "PGAM2_HUMAN", "id": "P15259-1", "name": "Phosphoglycerate mutase 2", "aln": "--------------------------------------MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVLKRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAG-LKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKRVLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBJ1-1", "uniprot_id": "PGAM1_MOUSE", "id": "Q9DBJ1-1", "name": "Phosphoglycerate mutase 1", "aln": "--------------------------------------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD-LTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25113-1", "uniprot_id": "PGAM1_RAT", "id": "P25113-1", "name": "Phosphoglycerate mutase 1", "aln": "--------------------------------------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD-LTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18669-1", "uniprot_id": "PGAM1_HUMAN", "id": "P18669-1", "name": "Phosphoglycerate mutase 1", "aln": "--------------------------------------MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD-LTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N0Y7-1", "uniprot_id": "PGAM4_HUMAN", "id": "Q8N0Y7-1", "name": "Probable phosphoglycerate mutase 4", "aln": "--------------------------------------MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYAD-LTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVCKAIEAVAAQGKAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGB6-1", "uniprot_id": "Q9VGB6_DROME", "id": "Q9VGB6-1", "name": "Phosphoglycerate mutase", "aln": "MLALARNSWCGQLLCRVANIEARCPFSKSSSGGKQAEKKGKYRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAETAKKFGEEKVKIWRRSFDTPPPPMEKDHEYYACIVEDPRYKDQLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISDKDIMSLNLPTGIPFVYELDESLKPLATLKFLGDPETVKKAMESVANQGKAK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00950-1", "uniprot_id": "PMG1_YEAST", "id": "P00950-1", "name": "Phosphoglycerate mutase 1", "aln": "----------------------------------------MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVD---PNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDENLKPSKPSYYL-DPEAAAAGAAAVANQGKK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*::***:* ** :* * * *..** * :** .. ::: *: ** .*. .* *. :: :** :*********.* * :**** *.** :.: :***:* ****:: . : : :* . :* ** .* * **:*:: *. .: * *:********:*:.**:* :*: * .**:*****:*:**::.*** . :* * *:. . :** *** ", "identical_positions": 97, "similar_positions": 66, "identity": "33.11%" }, { "cls_id": "homologset.agr.FB:FBgn0011272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2E9-1", "uniprot_id": "F1M2E9_RAT", "id": "F1M2E9-1", "name": "60S ribosomal protein L13", "aln": "MAPSRNGMILKPHFHKDWQP-VDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKMARTIGISVDPRRRNKSTESLQANVQRLKEYCSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARAITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41123-1", "uniprot_id": "RL13_RAT", "id": "P41123-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKMARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARAITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47963-1", "uniprot_id": "RL13_MOUSE", "id": "P47963-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26373-1", "uniprot_id": "RL13_HUMAN", "id": "P26373-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMVLKPHFHKDWQRRVATWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPVRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z10-1", "uniprot_id": "RL13_DANRE", "id": "Q90Z10-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILNPHFHKDWQKRVRTWFNQPARKIRRRKARQAKARRIAPRPVSGPLRPVVRCPTIRYHTKVRAGRGFTLEELKAAGINKKVARTIGISVDSRRRNRSTESLQANVQRLKEYRTKLIIFPRKAAKPKKGDSTEEELKMATQLTGPVMPIKK-VHKKEKARVISEDEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41126-1", "uniprot_id": "RL13_DROME", "id": "P41126-1", "name": "Large ribosomal subunit protein eL13", "aln": "MGKG-NNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPASGALRPVVRCPTIRYHTKLRAGRGFTLEELKGAGIGANFAKTIGIAVDRRRKNKSLESRQRNIQRLKEYRSKLILFPINEKKIRAGESSLEECKLATQLKGPVLPIKNEQPAVVEFREVTKDEKKFKAFATLRKARTDARLVGIRAKRAKEAAESEDAAKGDPKKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12690-1", "uniprot_id": "RL13A_YEAST", "id": "Q12690-1", "name": "Large ribosomal subunit protein eL13A", "aln": "MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAAKIAPRPLD-LLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRN------GKAPEAEQVLSAAAT---FPIAQ-PATDVEARAVQDNGE--SAFRTLRLARSEKKFRGIREKRAREKAE-AEAEK---KK---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40212-1", "uniprot_id": "RL13B_YEAST", "id": "P40212-1", "name": "Large ribosomal subunit protein eL13B", "aln": "MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAARAAKIAPRPLD-LLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRD------GKAPEAEQVLSAAAT---FPIAQ-PATDVEARAVQDNGE--SAFRTLRLARSEKKFRGIREKRAREKAE-AEAEK---KK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * : : *::* ** * . *:*..:*: *: * :* : *** . :**:**.**::*: *:******:* *:: **: *:****:** **:*:. * : *:****** :*:*:** . *.:. * ::: . :*: : : * : .: : .** :** **:: :: *** ***:* ** :. * ** ", "identical_positions": 78, "similar_positions": 62, "identity": "35.62%" }, { "cls_id": "homologset.agr.FB:FBgn0011273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06787-1", "uniprot_id": "CALM_YEAST", "id": "P06787-1", "name": "Calmodulin", "aln": "MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREVS-DGSGEINIQQFAALLSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P49258-1", "uniprot_id": "CALL_DROME", "id": "P49258-1", "name": "Calmodulin-related protein 97A", "aln": "MS-ELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMISQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :**********:**. ***:..*.*:: **.*:**:** .*:***::**: * : :.* *::*:** .:*::*::..*:*:*: ****:**::***:**.***:.*: .:***:** *:*:*:**.. **.* ** ::*. ::*: ", "identical_positions": 75, "similar_positions": 57, "identity": "50.34%" }, { "cls_id": "homologset.agr.FB:FBgn0011274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8H1-1", "uniprot_id": "D4A8H1_RAT", "id": "D4A8H1-1", "name": "Transcription factor RelB", "aln": "------------------MPSRRAAR-ESAPELGALGSSDIPSLS----RTTDELEIIDEYIKENGFGLDGAQLS---EMPRLVPRGPASLSSVTLGPAAPPPPATPPWNCTLG-----------------RLVS--PGPCP------RPYLVITEQPKQRGMRFRYECEGRSAGSILGE-SSTEASKTLPAIELR-DCGGLREVEVTACLVWKDWPHRVHPHSLVGKD----CTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAG--SLKNHQEVDMNVVRICFQASYRDQQGHL-HRMDPILSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSTAS------WEGRADFSQADVHRQIAIVFKTPPYEDLEISEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLG-------------------------------------------------ELSSSDPHGIESKRRKKK------------------PVFLDHFLPGHSSGLFLPPSALQSADTDFFPGTISLPGLEPPGGPDLLDDGFAYDPSAPTLFTMLDLLPPAPP-------LASAVVGNGGAGATVVESPGPEPLSLDSFAAPGPGDVGTASLVGSN-MFPNQYR-----------EAAFGGGLLSPGPEAT------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04863-1", "uniprot_id": "RELB_MOUSE", "id": "Q04863-1", "name": "Transcription factor RelB", "aln": "------------------MPSRRAAR-ESAPELGALGSSDLSSLSLTVSRTTDELEIIDEYIKENGFGLDGTQLS---EMPRLVPRGPASLSSVTLGPAAPPPPATPSWSCTLG-----------------RLVS--PGPCP------RPYLVITEQPKQRGMRFRYECEGRSAGSILGE-SSTEASKTLPAIELR-DCGGLREVEVTACLVWKDWPHRVHPHSLVGKD----CTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAG--SLKNHQEVDMNVVRICFQASYRDQQGHL-HRMDPILSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSTAS------WEGRADFSQADVHRQIAIVFKTPPYEDLEISEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLG-------------------------------------------------ELSSSDPHGIESKRRKKK------------------PVFLDHFLPGHSSGLFLPPSALQPADSDFFPASISLPGLEPPGGPDLLDDGFAYDPSAPTLFTMLDLLPPAPP-------LASAVVGSGGAGATVVESSGPEPLSLDSFAAPGPGDVGTASLVGSN-MFPNQYR-----------EAAFGGGLLSPGPEAT------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01201-1", "uniprot_id": "RELB_HUMAN", "id": "Q01201-1", "name": "Transcription factor RelB", "aln": "-MLRSGPASGPSVPTGRAMPSRRVARPPAAPELGALGSPDLSSLSLAVSRSTDELEIIDEYIKENGFGLDGGQPGPGEGLPRLVSRGAASLSTVTLGPVAPP-ATPPPWGCPLG-----------------RLVSPAPGPGP------QPHLVITEQPKQRGMRFRYECEGRSAGSILGE-SSTEASKTLPAIELR-DCGGLREVEVTACLVWKDWPHRVHPHSLVGKD----CTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAG--SLKNHQEVDMNVVRICFQASYRDQQGQM-RRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRAS------WEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLG-------------------------------------------------ELNSSDPHGIESKRRKKK------------------PAILDHFLPNHGSGPFLPPSALLP-DPDFFSGTVSLPGLEPPGGPDLLDDGFAYDPTAPTLFTMLDLLPPAPP-------HASAVVCSGGAGAVVGETPGPEPLTLDSYQAPGPGDGGTASLVGSN-MFPNHYR-----------EAAFGGGLLSPGPEAT------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P750-1", "uniprot_id": "A0A8M9P750_DANRE", "id": "A0A8M9P750-1", "name": "", "aln": "-------------MKDMNIPNGKAANGDLELDLINEYLLEKTNKELTITLPGPPPPPVDQDIQAVNPPPRNRRTT---NNPVLVSRGTAPQNSLSFDQVPTAHADGMAAMQSIRGAKGSSQRRGLASVATQRRIPQQTGTEHLEMFLEKPDLVVVEQPKERGMRFRYECEGRSAGSILGA-SSTDSNKTLPAIEIQGPIDNIKKVMVTVSLVTKDIPYRPHPHCLVGKD----CTDGICVIHINPHSNRRHSFANLGIQCVRRKELDASLQKRRNKNIDPFNTG--HSKSIEDMDMNVVRLCFQCELEQKNGDR-ITLNPVVSNPIYDKKATTTAELKINRLNVIRGPCTGKTEIYMLCDKVQKDDIEIIFSIED------WEAKAEFAQTDVHRQIAIVFKSPPFREQDILEETEVNVCLRRMSDRMDSEPVKFTYVPDNADPYGVNRKRKMKTDVKFS-------------------------------------------------ESCNIPQSQDLLMNDPGT------------------SQQFDPFYPTPECNVSSAPIAVPLQDGGIQMPSLTVEEMFYNEDFKQEDGCISMDQEALSSFLLQCLGPHG----------SDQVYNQLSSELNLVLDGADINVNQTMLNMASINDAHFSQMVSENQPYPADLEN--------IEEFMFSSVKTENNPDL-------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7TQN4-1", "uniprot_id": "TF65_RAT", "id": "Q7TQN4-1", "name": "Transcription factor p65", "aln": "---------------------------------------------------------MDDLFPLIFPSEPAQASG--------------------------------------------------------------------------PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGE-RSTDTTKTHPTIKIN---GYTGPGTVRISLVTKDPPHRPHPHELVGKD----CRDGFYEAELCPDRCI-HSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVP-IEEQR-GDYDLNAVRLCFQVTVRDPSGRP-LRLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFK-----SIMKKSPFNG---------------------------PTEPRPPPRRIAVPSRGPTSVPKPAPQPYAFSTS----LSTINFDEFSPMVLPPGQISNQALALAPSSAPVLAQTMVPS--SAMVPSLAQPPAPVPVLAPGPPQSLSAPVPKSTQAG----EGTLSEALLHLQFDADEDLGALLGNNTDPGVFTDLASVDNSEFQQLLNQGVAMSHSTAEPML-----MEYPEAITRLVTGSQR-----PPDPAPATLGTSG-----------------LPNG-----------------LSGDEDFSSIADMDFSALLS--QISS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04207-1", "uniprot_id": "TF65_MOUSE", "id": "Q04207-1", "name": "Transcription factor p65", "aln": "---------------------------------------------------------MDDLFPLIFPSEPAQASG--------------------------------------------------------------------------PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGE-RSTDTTKTHPTIKIN---GYTGPGTVRISLVTKDPPHRPHPHELVGKD----CRDGYYEADLCPDRSI-HSFQNLGIQCVKKRDLEQAISQRIQTNNNPFHVP-IEEQR-GDYDLNAVRLCFQVTVRDPAGRP-LLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFK-----SIMKKSPFNG---------------------------PTEPRPPTRRIAVPTRNSTSVPKPAPQPYTFPAS----LSTINFDEFSPMLLPSGQISNQALALAPSSAPVLAQTMVPS--SAMVP-LAQPPAPAPVLTPGPPQSLSAPVPKSTQAG----EGTLSEALLHLQFDADEDLGALLGNSTDPGVFTDLASVDNSEFQQLLNQGVSMSHSTAEPML-----MEYPEAITRLVTGSQR-----PPDPAPTPLGTSG-----------------LPNG-----------------LSGDEDFSSIADMDFSALLS--QISS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04206-1", "uniprot_id": "TF65_HUMAN", "id": "Q04206-1", "name": "Transcription factor p65", "aln": "---------------------------------------------------------MDELFPLIFPAEPAQASG--------------------------------------------------------------------------PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGE-RSTDTTKTHPTIKIN---GYTGPGTVRISLVTKDPPHRPHPHELVGKD----CRDGFYEAELCPDRCI-HSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVP-IEEQR-GDYDLNAVRLCFQVTVRDPSGRP-LRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFK-----SIMKKSPFSG---------------------------PTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSS----LSTINYDEFPTMVFPSGQIS-QASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG----EGTLSEALLQLQFD-DEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPML-----MEYPEAITRLVTGAQR-----PPDPAPAPLGAPG-----------------LPNGL----------------LSGDEDFSSIADMDFSALLS--QISS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BI19-1", "uniprot_id": "A0A8M2BI19_DANRE", "id": "A0A8M2BI19-1", "name": "", "aln": "---------------------------------------------------------MDGMFHQWGTSQVPQGP---------------------------------------------------------------------------PHVEIIEQPKSRGMRFRYKCEGRSAGSIPGE-KSNDTTKTHPAIRVH---NYSGPVRVRISLVTKNQPYKPHPHELVGKD----CKHGYYEADLQ-ERRI-HSFQNLGIQCVKKKDVGEAVSCRLQTQNNPFKIPDAKIWE-EEFDLNAVRLCFQVSITLSSGDL-FPLEPVVSQPIYDNRAPNTAELKICRVNRNSGSCRGGDEIFLLCDKVQKEDIEVRFFLDS------WESKGSFSQADVHRQVAIVFRTPPYCDTNLTEPLRVKMQLRRPSDREVSEPMDFQYLPSDPDEHRLMEKRKRTEGMLHNLKLSSIITGSSMSA---------------------------ERRPFPTAKRTLPVSKQPVAASAPASVPAVSAAPPLKPPPTSFFSPPPGQLFTQQKMEPSPLPASSSDIWKYLQAMSVDSQPKAVPVLPFPSGTVSTALPTCLTQAFPTVNLSDLHDCTIKSSTIAEPAPLKDPEPAPEVQSAFTIRMN-NTFPDENLPDFPSFSELQGSGDSISNEDIQAILDQSTRQKLPEPCCELPSAADLSWMGYHPNFPGLHGNVTA-----------------QDNGAGEAAAAPS-------VLDDLVELTSMEDDRFMSLFESCDMSTFHF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M5R1-1", "uniprot_id": "F1M5R1_RAT", "id": "F1M5R1-1", "name": "", "aln": "--------------------------------------------------------------------MASSGYN--------------------------------------------------------------------------PYVEIIEQPRQRGMRFRYKCEGRSAGSIPGE-RSTDNNRTYPSIQIM---NYYGKGKVRITLVTKNDPYKPHPHDLVGKD----CRDGYYEAEFGPERRP-LFFQNLGIRCVKKKEVKEAIILRISAGINPFNVPEQQLLDIEDCDLNVVRLCFQVFLPDEHGNFTTALPPIVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLND------WEAKGIFSQADVHRQVAIVFRTPPYCR-AIVEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDAYGNKSKKQKTTLIFQ-----KLLQDCEKR--------------------------IIPSHFPEKTRAVPLESIGETRFIKKESNLFSHGTVLPETPRSSGVPGQAEPYYSSSGSISNALPHHPSAMPSMVHQPASWSPVTHPTSHPGSTNTLSSFPAGQLSSNSQGVLPFLDGA-GMNDLSASNACLFS-TDNLARMETPSMSPTDLYSISDVNMLTNRPVSVMTSSTDGMGDTDHPRLVSVN--LENPSCNSRLDPRDPRQLHQMSTASMSAAGTSSSSVFVSQSDTFNRPHFSCIDNGLTNEPGLAN--DAHHPNFAQSSQYSGIDALQSEQLGDSFEYSFFKI------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15307-1", "uniprot_id": "REL_MOUSE", "id": "P15307-1", "name": "Proto-oncogene c-Rel", "aln": "--------------------------------------------------------------------MASSGYN--------------------------------------------------------------------------PYVEIIEQPRQRGMRFRYKCEGRSAGSIPGE-RSTDNNRTYPSVQIM---NYYGKGKIRITLVTKNDPYKPHPHDLVGKD----CRDGYYEAEFGPERRP-LFFQNLGIRCVKKKEVKGAIILRISAGINPFNVGEQQLLDIEDCDLNVVRCVFMFFLPDEDGNFTTALPPIVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLND------WEARGVFSQADVHRQVAIVFKTPPYCK-AILEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDAYGNKSKKQKTTLIFQ-----KLLQDCG--------------------------------HFTEKPRTAPLGSTGEGRFIKKESNLFSHGTVLPEMPRSSGVPGQAEPYYSSCGSISSGLPHHPPAIPSVAHQPTSWPPVTHPTSHPVSTNTLSTFSAGTLSSNSQGILPFLEGP-GVSDLSASNSCLYN-PDDLARMETPSMSPTDLYSISDVNMLSTRPLSVMAPSTDGMGDTDNPRLVSIN--LENPSCNARLGPRDLRQLHQMSPASLSAG-TSSSSVFVSQSDAFDRSNFSCVDNGLMNEPGLSD--DANNPTFVQSSHYS-VNTLQSEQLSDPFTYGFFKI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04864-1", "uniprot_id": "REL_HUMAN", "id": "Q04864-1", "name": "Proto-oncogene c-Rel", "aln": "--------------------------------------------------------------------MASGAYN--------------------------------------------------------------------------PYIEIIEQPRQRGMRFRYKCEGRSAGSIPGE-HSTDNNRTYPSIQIM---NYYGKGKVRITLVTKNDPYKPHPHDLVGKD----CRDGYYEAEFGQERRP-LFFQNLGIRCVKKKEVKEAIITRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLND------WEAKGIFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLFQ-----KLCQDHVETGFRHVDQDGLELLTSGDPPTLASQSAGITVNFPERPRPGLLGSIGEGRYFKKEPNLFSHDAVVREMP--TGVSSQAESYYPSPGPISSGLSHHASMAP---LPSSSWSSVAHPTPRSGNTNPLSSFSTRTLPSNSQGIPPFLRIP-VGNDLNASNACIYNNADDIVGMEASSMPSADLYGISDPNMLSNCSVNMMTTSSDSMGETDNPRLLSMN--LENPSCNSVLDPRDLRQLHQMSSSSMSAGANSNTTVFVSQSDAFEGSDFSCADNSMINESGPSNSTNPNSHGFVQDSQYSGIGSMQNEQLSDSFPYEFFQV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P98149-1", "uniprot_id": "DIF_DROME", "id": "P98149-1", "name": "Dorsal-related immunity factor Dif", "aln": "MFEEAFGDIQEIINASMELNGGATGGGSVAGAVGGGGAAHHILSQSTSLPVMPSHIPLHLQNQNMNQNLPEPSAR------------------------------------------------------------------------SGPHLRIVEEPTSNIIRFRYKCEGRTAGSIPGMNSSSETGKTFPTIEVC---NYDGPVIIVVSCVTSDEPFRQHPHWLVSKEEADACKSGIYQKKLPPEERR-LVLQKVGIQCAKKLEMRDSLVERERRNIDPFNAKFDHKDQIDKINRYELRLCYQAFIT--VGNSKVPLDPIVSSPIYGK----SSELTITRLCSCAATANGGDEIIMLCEKIAKDDIEVRFYETDKDGRETWFANAEFQPTDVFKQMAIAFKTPRYRNTEITQSVNVELKLVRPSDGATSAPLPFEYYPNPELLTKHNRRVAQKTVESLKR-----------------------------------------------SLMSTNLHPSKQVKTSSQYTIFSKPQIATTTPQTQVSPGMPLMFPGGSPNFVQDIKMENGFMDVDSQSSQCPSVERNFASPRSNCSTVDSIPPMQMGQNQTHLYLPDATNFTFNGNFASPSSNCSTVDSIPPFQIGQRNNHMYLPENSNFPVNGCSPTHFSGGSMTPINNNNNVLINNNNNDFLSQKMSAISIPPQGNFGIKQVYQQTQQFLPQLQPESIPYLAQSHPEQSQYQQQQQPQEQQPPADEPTQSFSDLISSSIGMAPIDTSELIQDIEAELNSLGIQPFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : *:* .. :****:****:**** * *.: :* *::.: . : * .: *.: *** **.*: * * : . : ::**:*.:: :: :: : :*:: . : :* : * : *::* *::.: ::** * *: .. * *: :**:*: *:**.: * . * ... * :**.:*:**.*::* : : *.: * * :* * .: * * * : : . ", "identical_positions": 68, "similar_positions": 84, "identity": "8.54%" }, { "cls_id": "homologset.agr.FB:FBgn0011276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LDL2-1", "uniprot_id": "A0ABK0LDL2_RAT", "id": "A0ABK0LDL2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRKIFTNTRERWRQQSVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQT-------------------GIAAQG---------------------------------------NILGLFP--------------------HKPHLP-DVGESSLLNGYRVS--------SPG--------PSHGAP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62282-1", "uniprot_id": "TAL2_MOUSE", "id": "Q62282-1", "name": "T-cell acute lymphocytic leukemia protein 2 homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRKIFTNTRERWRQQSVNNAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLHQT-------------------GVAAQG---------------------------------------NILGLFP--------------------PKTRLP-DEDDRTLLNDYRVP--------SPG--------PSHGAP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16559-1", "uniprot_id": "TAL2_HUMAN", "id": "Q16559-1", "name": "T-cell acute lymphocytic leukemia protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQT-------------------GVAAQG---------------------------------------NILGLFP--------------------QGPHLP-GLEDRTLLENYQVP--------SPG--------PSHHIP--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4X2-1", "uniprot_id": "Q9W4X2_DROME", "id": "Q9W4X2-1", "name": "", "aln": "---------------MAWLPSSSNGADNADERSTASSGSSGHSQT-------------------NESPRSGHLNGNGSMRDTAAGRHPPALLRHATPHLQPKTESISDGDGDAELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLSSSPRSHSRNGLLTAPASSGSSVGGSGGGGGNGSGGNASSGGGSGVGATGGVRKVFTNTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRAQMEPNNNDNRMANGHAADGENLENPDVPPVRHIKCERTDGQMHRNGIGHGHANGNAGNDLLMIAPGAVVKSELLLESTLPLGHPLNGPPLPLTTAPLAMAETQRISGTVSGVKSASGRSSKRRLKPEGGATDLSLGKRRRT----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q66HH3-1", "uniprot_id": "LYL1_RAT", "id": "Q66HH3-1", "name": "Protein lyl-1", "aln": "-------------MCPPQAQAEVGSAMT-EKTEMVCTSSPAPAPP-----------------SKPASPGPLPAEEVDHRN-TCNPWLPPGVPVINLGHTRPTGAAMPTTELSAFRPS------------LLQLAALGTAPPTLALH----YHPHPFLNSVYIGPAGPFSIFPNSRLKRRPS--HGELDLVDGHQPQKVARRVFTNSRERWRQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAVLAS------------------GPSAPGSRKPP--------------------------------AHRGVEGNAR-------------------CGAGHRVEAAR-SQPVLPGDC--------DGD--------PNGSVRPIKMEQTALSPEVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27792-1", "uniprot_id": "LYL1_MOUSE", "id": "P27792-1", "name": "Protein lyl-1", "aln": "-------------MCPPQARAEVGSAMT-EKTEMVCASSPAPAPP-----------------SKPASPGPLSTEEVDHRN-TCTPWLPPGVPVINLGHTRPIGAAMPTTELSAFRPS------------LLQLTALGRAPPTLAVH----YHPHPFLNSVYIGPAGPFSIFPNSRLKRRPS--HSELDLADGHQPQKVARRVFTNSRERWRQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQTAVLTS------------------GPSAPGSRKPP--------------------------------ARRGVEGSAR-------------------FGAGHRVEAAR-SQPVLPGDC--------DGD--------PNGSVRPIKLEQTSLSPEVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12980-1", "uniprot_id": "LYL1_HUMAN", "id": "P12980-1", "name": "Protein lyl-1", "aln": "-------------MCPPQAQAEVGPTMT-EKAEMVCAPSPAPAPP-----------------PKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMPTTELGTLRPP------------LLQLSTLGTAPPTLALH----YHPHPFLNSVYIGPAGPFSIFPSSRLKRRPS--HCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALAA------------------GPTPPGPRKRP--------------------------------VHRVPDDGAR-------------------RGSGRRAEAAARSQPAPPADP--------DGS--------PGGAARPIKMEQTALSPEVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TRC3-1", "uniprot_id": "A0AB32TRC3_DANRE", "id": "A0AB32TRC3-1", "name": "Stem cell protein", "aln": "MSSDDGEALLMEEQHPPRSSPASPSVLQPDPPAHACSTPPDHAEPRAQDTQEPGATGAETDSRRSSSSRSPHCTTTDSRRGSSSASLPAHIPVISLAHSKPPLPPLPLLAALHPAPPPPH---GPAELRLAQLSCLTGSSPAAALLPPAFLQTHPFISSSFLMPPAGFGIFSNARMKRRPST-HFEVEIRSDGPPQKLARRVFTNSRERWRQQNVNGAFSELRKLIPTHPPDRKLSKNEILRLAMKYIDFLEQLLNDQSQPEET------------------GQHAH-AHTPS--------------------------------THSLLLLTAS-------------------SGSSCYGDTDS-EESTGPRAC--------STD--------PKHSGEPILALTVSGGQR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::***:******* *..**::****:******:****** ** *::** :* :* * * . . . . * ", "identical_positions": 40, "similar_positions": 18, "identity": "9.66%" }, { "cls_id": "homologset.agr.FB:FBgn0011277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZN93-1", "uniprot_id": "D3ZN93_RAT", "id": "D3ZN93-1", "name": "", "aln": "MMLNSDTMELDLPPTHSETESGFSDCGGGPGPD-----------------------------GAGSGDPG----VGQVRSLELGESGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02576-1", "uniprot_id": "HEN1_MOUSE", "id": "Q02576-1", "name": "Helix-loop-helix protein 1", "aln": "MMLNSDTMELDLPPTHSETESGFSDCGGGPGPD-----------------------------GAGSGDPG----VVQVRSSELGESGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02575-1", "uniprot_id": "HEN1_HUMAN", "id": "Q02575-1", "name": "Helix-loop-helix protein 1", "aln": "MMLNSDTMELDLPPTHSETESGFSDCGGGAGPD-----------------------------GAGPGGPG----GGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PH26-1", "uniprot_id": "M9PH26_DROME", "id": "M9PH26-1", "name": "", "aln": "MVYDMSHMAAGPPQSISLSRYYLVDDDEMIGPNNPHLVNEDYAASTTLDIDKRFQARMACETAAQPAPPPPPTPAPRRRTTPIAHLDPSELVGLSREERRRRRRATLKYRTAHATRERIRVEAFNVSFAELRKLLPTLPPDKKLSKIEILKLAICYIAYLNHVLETPXDSAGASSFATSCLFNEANFFAPP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : . * . * : * :. : * . **: .* .. * : * .. . .:* ************* ******************::***********************:******:******:. ", "identical_positions": 77, "similar_positions": 25, "identity": "40.31%" }, { "cls_id": "homologset.agr.FB:FBgn0011278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1XID0-1", "uniprot_id": "LBX1_RAT", "id": "Q1XID0-1", "name": "Transcription factor LBX1", "aln": "------------------------------------------------------------------------------------------------MTSK-EDGKA-----APGEERR-RSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHL----LAAADKHAPGGLPLAGRALLSQTSPLCALEELAS--------KTFKGLEVSV-----------------------------------------------------------------------------LQAAEGRDGMTI-----------------------------------------FGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPS--GQMDIVALAELEQNSEASGGGGGGGGGGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPASPLTDQRASSQDCSEDEEDEEIDVDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52955-1", "uniprot_id": "LBX1_MOUSE", "id": "P52955-1", "name": "Transcription factor LBX1", "aln": "------------------------------------------------------------------------------------------------MTSK-EDGKA-----APGEERR-RSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHL----LAAADKHAPGGLPLAGRALLSQTSPLCALEELAS--------KTFKGLEVSV-----------------------------------------------------------------------------LQAAEGRDGMTI-----------------------------------------FGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPS--GQMDIVALAELEQNSEASGGGGG---GGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPASPLTDQRASSQDCSEDEEDEEIDVDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52954-1", "uniprot_id": "LBX1_HUMAN", "id": "P52954-1", "name": "Transcription factor LBX1", "aln": "------------------------------------------------------------------------------------------------MTSK-EDGKA-----APGEERR-RSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHL----LAAADKHAQGGLPLAGRALLSQTSPLCALEELAS--------KTFKGLEVSV-----------------------------------------------------------------------------LQAAEGRDGMTI-----------------------------------------FGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPS--GQMDIVALAELEQNSEATAGGGG----GCGRAKSRPGSPVLPPGAPKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM39-1", "uniprot_id": "Q6ZM39_DANRE", "id": "Q6ZM39-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MTSK-EDAKG-----ASVEDRR-RSPLDHLPPPANSNKPLTPFSIEDILNKPSVKRSYTICGTAHL----LSSGEKHPSTGHPLSNRALLTQTSPLCALEELAS--------KTFKGLEVSV-----------------------------------------------------------------------------LQAAEGRDGMTL-----------------------------------------FGQRNTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKAVGNV--PFEKMAKLADLEKRVNGTLGDSS------AVSPSRSN--------HEHEGTNKLHMSPSSPYTDH-TTSKECSEDE-DEEIDVDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FDX5-1", "uniprot_id": "LBX1B_DANRE", "id": "E7FDX5-1", "name": "Transcription factor LBX1b", "aln": "------------------------------------------------------------------------------------------------MTTI-KVVKI-----CGAMESRGLNPLDHLPPPASSNKPLTPFSITDILSKPTVKR----FHRIHR----LPASDRVRQS-ITVSRQTLITQASPLCALQELAS--------KTFKGLELGV-----------------------------------------------------------------------------LQAAEGKDGLKL-----------------------------------------FGQRDSPKKRRKSRTAFTNHQLYELEKRFLHQKYLSPADRDQIAHQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESVRSTGLV--PLDKLAKLADLERCAAAGATGNP-----GPQCSPRLG--------HEYKTVHKLCLSPMSSLSDH--TSQDCSEDE-EVEIDVDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q804R0-1", "uniprot_id": "LBX2_DANRE", "id": "Q804R0-1", "name": "Transcription factor LBX2", "aln": "------------------------------------------------------------------------------------------------MTSSSKDMKAGSVLQSSGEERR-RGPLDQLPPPANSNKPLTPFSIEDILNKPSVKKS---VGSLCP----PRVLEKVTGS--SASRNGISAPSSPLCALEELAS--------KTFKGLEVSV-----------------------------------------------------------------------------IQAAEGREHINA-----------------------------------------FGQRQASKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESLKKIPPQ--ALQKLVSMEDMED----AHGGSG------PISPSLSP-----------------RAFPQSPSSSRGQTTDEFSEED--EEIEVDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A7L0-1", "uniprot_id": "D4A7L0_RAT", "id": "D4A7L0-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MNSG-----------------------------RQRRTP---FSIADILGRSMVPG----APSEPR----LPEAG--------------PDPASPLCALEELAS--------KTFQGHSPRA-----------------------------------------------------------------------------PQPSEGRAVPEAP----------------------------------------PGPGTGVRRRRKSRTAFTPQQVLELERRFVFQKYLAPSERDGLAARLGLANAQVVTWFQNRRAKLKRDVEEMRADLASLCGLSP---GVLCPPALPDSASSPDLQPTPSG----------------------------------PDS--------EPGLSDEE----IQVDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUN8-1", "uniprot_id": "LBX2_MOUSE", "id": "Q9WUN8-1", "name": "Transcription factor LBX2", "aln": "------------------------------------------------------------------------------------------------MNSV-----------------------------HQRRTP---FSIADILGPSMVPE----APSAPQ----LPEAG--------------PDPASPLCALEELAS--------KTFLGHSPRAT----------------------------------------------------------------------------PQPSEGRAAPEAP----------------------------------------PGPGAGVRRRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLAARLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLCGLSP---GVLCYPALPDSTSSPD--PGPSG----------------------------------PDS--------EPNLSDEE----IQVDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XYB7-1", "uniprot_id": "LBX2_HUMAN", "id": "Q6XYB7-1", "name": "Transcription factor LBX2", "aln": "------------------------------------------------------------------------------------------------MNSG-----------------------------REPRTPRTLLSIADILAPRMVPR----APSAPQ----LPESG--------------PGPTSPLCALEELTS--------KTFRGLDARA-----------------------------------------------------------------------------LQPSEGRAGPDA-----------------------------------------LGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSP---EVLCSLALPEGAPDPGLCLGPAG----------------------------------PDS--------RPHLSDEE----IQVDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KS77-1", "uniprot_id": "Q7KS77_DROME", "id": "Q7KS77-1", "name": "", "aln": "MLCPPTMRPASPAESEISVGGAPSPLPTQHHTHPHSHPHPLQHPRASTIDLLQQQQLLMQHHAAAAAAAAAAASGLTRSAVGNLPEDYFHPLKRLRMSSSSSEPRD-----HTPSPPSAVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVNDLSILKKKPMHESDMVG--------------------------------LAAAAAAAGMVVPVPGSVPMGGAPPK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: . :** *** * .* * . . : * . . ** . :::******** :*: ***:**:.****:*::** :* ***:****:********* ***:**:: *. * : . : ", "identical_positions": 57, "similar_positions": 32, "identity": "10.96%" }, { "cls_id": "homologset.agr.FB:FBgn0011284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62702-1", "uniprot_id": "RS4X_MOUSE", "id": "P62702-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62701-1", "uniprot_id": "RS4X_HUMAN", "id": "P62701-1", "name": "Small ribosomal subunit protein eS4, X isoform", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62703-1", "uniprot_id": "RS4X_RAT", "id": "P62703-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22090-1", "uniprot_id": "RS4Y1_HUMAN", "id": "P22090-1", "name": "Small ribosomal subunit protein eS4, Y isoform 1", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKICMQRFIKIDGKVRVDVTYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITVEEAKYKLCKVRKITVGVKGIPHLVTHDARTIRYPDPVIKVNDTVQIDLGTGKIINFIKFDTGNLCMVIGGANLGRVGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGNGNKPWISLPRGKGIRLTVAEERDKRLATKQSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TD47-1", "uniprot_id": "RS4Y2_HUMAN", "id": "Q8TD47-1", "name": "Small ribosomal subunit protein eS4, Y isoform 2", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKICMQHFLKIDGKVRVDITYPAGFIDVISIEKTGEHFRLVYNTKGCFAVHRITVEEAKYKLCKVRKITVGTKGIPHLVTHDARTIRYPDPLIKVNDTVQIDLGTGKITSFIKFDTGNVCMVIAGANLGRVGVITNRERHPGSCDVVHVKDANGNSFATRISNIFVIGNGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H9-1", "uniprot_id": "RS4X_DANRE", "id": "Q642H9-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPTGFMDVVSIEKTGENFRLIYDVKGRFTVHRITNEEAKYKLCKVRKILIGTKGIPHLVTHDARTIRYPDPLIKVNDTIRIDLDTGKITDFIKFETGNMCMVTGGANLGRIGVITNREKHPGSFDVVHVKDSIGNSFATRLSNIFVIGKGNKPWVSLPRGKGVRLTIAEERDKRLAAKQSSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41042-1", "uniprot_id": "RS4_DROME", "id": "P41042-1", "name": "Small ribosomal subunit protein eS4", "aln": "MARGPKKHLKRLAAPKAWMLDKLGGVFAPRPSTGPHKLRESLPLLIFLRNRLKYALNGAEVTKIVMQRLVKVDGKVRTDPTYPAGYMDVITLEKTGEFFRLVYDVKGRFVIHRISAEEAKYKLCKVKKTQLGAKGVPFLVTHDGRTIRYPDPLIHANDSVQVDIASGKITDYIKFDSGNLCMITGGRNLGRVGTVVNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGVKLSIAEERDKRLAAKTH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX36-1", "uniprot_id": "RS4B_YEAST", "id": "P0CX36-1", "name": "Small ribosomal subunit protein eS4B", "aln": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX35-1", "uniprot_id": "RS4A_YEAST", "id": "P0CX35-1", "name": "Small ribosomal subunit protein eS4A", "aln": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********:***: *:**** * :*****:*******.***::**********.* **. * **: :*:*****.* ***:*::**:::: *.* ***:*:.** *.:***: ***.*** **:* :* **:*.:****.******** *:.**::::*: :*** .:***::*:: : .* ****:*.:.::*:* *. *:**:**: .: *.**:.*:*:**: .**::***:***::*::*****:* * : ", "identical_positions": 149, "similar_positions": 80, "identity": "56.65%" }, { "cls_id": "homologset.agr.FB:FBgn0011286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0LPN4-1", "uniprot_id": "RYR2_RAT", "id": "B0LPN4-1", "name": "Ryanodine receptor 2", "aln": "MADA--GEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEG-------KFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNSS------WRVDAAFQQTLWSVAPISS--GSEAAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFAFRSS---KEKLDAGVR-KEVDGMGTSEIKYGDSICYIQHVDTGLWLTYQAVDVKSARMGSIQ-RKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFLFNRFIRGLDALSKRAKLPTVD----LPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAG-REAGESWKSILNSLYELLAALIRGNRKNCAQFSGS--LDWLISRLERLEAS--SGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSS--PNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAACYEAVLPKEKLKVEHSREYKQ-ERTYTRDLLGPTVSLTQAAFTPVPVDTSQIVLPPHLERIRERLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFCKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMKLP-KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYHLEAPDQDHASRAEVCSGTG--ERFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDLELGSDERAFAFDGFKAQRWHQG-NEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVG-DGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSNHEH-IEVTRIDGTIDSSPCLKVTQKSFGSQNSNT-DIMFYRLSMPIECAEVFSKSVAGGIPGAGFYGP------------------------------------------KNDLEDFDVDSDFEVLMKTAHGHLVPDRMDKDKETPKP------------------EFNNHKDYA----------------------------QEKPSRLKQRFLLRRTKPDYSTSHSARLTEDVLA-----------------------DDRDDYEYLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGE---SMSPGQ-GRNNSNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFP------DENKKHGLPGIGLSTSLRPRMCFSSPSFVSISNECY---------------QYSPEFPLDILKAKTIQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFK--------------------------------------------------------EAATPEEEGGAPEKEISID--------------DSKLE--VKEEAKAGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFKDD----KSECPCPEEIRDQLLDFHEDLMTHCGIELDED-----GSLDGSNDLTIRGRLLSLVEKVTYLKKKQAEKPVAS--DSRKSSSLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIG-GLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------ESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIKIAEDP------SRDGPSPTSGSSKTLDAEE--EEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGKVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAG-TEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWSNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSM--MEKQSSMDSEGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKIQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGD--SMALYNRTRRISQTSQVS-IDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDIFKFLQISGYAVSRGFKDLDLD-----TPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSRS----KGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCTGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLDSVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRSQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSCYRILTSLYALGTS---------KSIYVERQRSALGECLAAFAGAFPIAFLETHLDKHNVYSIYNTRSSRERAALSLPANVEDVCPNIPSLEKLMTEIIELAESG--IRYTQMPHMMEVVLPMLCSYMSRWWEHGPEN----HPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLK---AEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEP-NPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDTKS-KMS-----KAAISDQERKKM--KRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALAKNRFSLKDTEEEVRDVIRSNIHLQGKLE-DPAIRWQMALYKDL-----------------PNRAEDTSDPERTVERVLDIANVLFHLEQ------------VEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGS----ELPEEDEAMKRVDPLHQLILLFSRTALTEKC-KLEEDFLYMAYADIMAKSCHDEEDDDGEEE-------VKSFEVTGSQRSKEKEMEKQKLLYQQARLHDRGAAEMVLQTFSASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEG--------SGEKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQ--------------------DSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERSANKEE------SEKERPEEQAPRMGFFSLLTVQSALFALRYNVLTLVRMLSLKSLKKQMKRMKKMTVKDMVSAFFSSYWSVFVTLLHFVASVCRGFFRIVSSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGDEEEGERKPLESALPSEDLTDLKELTEESDLLSDIFGLDLKREG---GQYKLIPHNPNAGLSDLMTN--PIPVPEVQEKFQEQKVKEE-----------KEGKEETKSEPEKAEGEDGEK--------EEKAKDDKGKQKLRQLHT---HRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTSSVVEGKE------------------LPTRTSSDAAKVTTSLDS------------SPHRIIAVHYVLEESSGYMEPTLRILAILHTIISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKK-PKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q401-1", "uniprot_id": "RYR2_MOUSE", "id": "E9Q401-1", "name": "Ryanodine receptor 2", "aln": "MADA--GEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNSS------WHVDAAFQQTLWSVAPISS--GSEAAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFAFRSS---KEKLDVGVR-KEVDGMGTSEIKYGDSICYIQHVDTGLWLTYQAVDVKSARMGSIQ-RKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFLFNRFIRGLDALSKKVKLPTID----LPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAG-REAGESWKSILNSLYELLAALIRGNRKNCAQFSGS--LDWLISRLERLEAS--SGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSS--PNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAACYEAVLPKEKLKVEHSREYKQ-ERTYTRDLLGPTVSLTQAAFTPVPVDTSQIVLPPHLERIRERLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFCKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMKLP-KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYHLEAPDQDHASRAEVCSGTG--ERFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDLELGSDDRAFAFDGFKAQRWHQG-NEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVG-DGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSNHEH-IEVTRIDGTIDSSPCLKVTQKSFGSQNNNT-DIMFYRLSMPIECAEVFSKSVAGGLPGAGFYGP------------------------------------------KNDLEDFDVDSDFEVLMKTAHGHLVPDRIDKDKETPKP------------------EFNNHKDYA----------------------------QEKPSRLKQRFLLRRTKPDYSTGHSARLTEDVLA-----------------------DDRDDYEYLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGE---SMSPGQ-GRNNSNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFP------DENKKHGLPGIGLSTSLRPRMRFSSPSFVSISNDCY---------------QYSPEFPLDILKAKTIQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFK--------------------------------------------------------EAAVPEEEGGTPEKEISIE--------------DAKLE--GEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTREFRSPPQEQINMLLNFKDD----KSECPCPEEIRDQLLDFHEDLMTHCGIELDED-----GSLDGSNDLTIRGRLLSLVEKVTYLKKKQAEKPVAS--DSRKCSSLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIG-GLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------ESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIKIAEDP------SRDGPSPTSGSSKTLDIEE--EEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGKVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAG-TEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSM--MEKQSSMDSEGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKIQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGD--SMALYNRTRRISQTSQVS-IDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDIFKFLQISGYVVSRGFKDLDLD-----TPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSRS----KGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCTGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLDSVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRSQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSCYRILTSLYALGTS---------KSIYVERQRSALGECLAAFAGAFPIAFLETHLDKHNVYSIYNTRSSRERAALSLPANVEDVCPNIPSLEKLMTEIIELAESG--IRYTQMPYMMEVVLPMLCSYMSRWWEHGPEN----HPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLK---AEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEP-NPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDTKS-KMS-----KAAISDQERKKM--KRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALAKNRFSLKDTEEEVRDIIRSNIHLQGKLE-DPAIRWQMALYKDL-----------------PNRTEDPSDPERTVERVLGIANVLFHLEQKSKYTGRGYFSLVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGA----ELPEEDEAMKRVDPLHQLILLFSRTALTEKC-KLEEDFLYMAYADIMAKSCHDEEDDDGEEE-------VKSFE--------EKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEG--------SGEKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQ--------------------DSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERLANKEE------SEKERPEEQAPRMGFFSLLTIQSALFALRYNVLTLVRMLSLKSLKKQMKRMKKMTVKDMVLAFFSSYWSVFVTLLHFVASVCRGFFRIVSSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGDEEEGERKPLESALPSEDLTDLKELTEESDLLSDIFGLDLKREG---GQYKLIPHNPNAGLSDLMTN--PVPVPEVQEKFQEQKAKEE-----------KEEKEETKSEPEKAEGEDGEK--------EEKAKDEKSKQKLRQLHT---HRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTSSVVEGKE------------------LPTRTSSDTAKVTNSLDS------------SPHRIIAVHYVLEESSGYMEPTLRILAILHTIISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKK-PKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92736-1", "uniprot_id": "RYR2_HUMAN", "id": "Q92736-1", "name": "Ryanodine receptor 2", "aln": "MADG--GEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNGS------LHVDAAFQQTLWSVAPISS--GSEAAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFTFRSS---KEKLDVGVR-KEVDGMGTSEIKYGDSVCYIQHVDTGLWLTYQSVDVKSVRMGSIQ-RKAIMHHEGHMDDGISLSRSQHEESRTARVIRSTVFLFNRFIRGLDALSKKAKASTVD----LPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAG-REAGESWKSILNSLYELLAALIRGNRKNCAQFSGS--LDWLISRLERLEAS--SGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSS--PNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQ-ERTYTRDLLGPTVSLTQAAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAEDKVKKMKLP-KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARAEVCSGTG--ERFRIFRAEKTYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQG-NEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVG-DGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSNHEH-IEVTRIDGTIDSSPCLKVTQKSFGSQNSNT-DIMFYRLSMPIECAEVFSKTVAGGLPGAGLFGP------------------------------------------KNDLEDYDADSDFEVLMKTAHGHLVPDRVDKDKEATKP------------------EFNNHKDYA----------------------------QEKPSRLKQRFLLRRTKPDYSTSHSARLTEDVLA-----------------------DDRDDYDFLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGE---SMSPGQ-GRNN-NGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEYIVPMTEETKSITLFP------DENKKHGLPGIGLSTSLRPRMQFSSPSFVSISNECY---------------QYSPEFPLDILKSKTIQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFK--------------------------------------------------------EAATPEEESDTLEKELSVD--------------DAKLQGAGEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFKDD----KSECPCPEEIRDQLLDFHEDLMTHCGIELDED-----GSLDGNSDLTIRGRLLSLVEKVTYLKKKQAEKPVES--DSKKSSTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIG-GLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------ESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIKIAEDP------SRDGPSPNSGSSKTLDTEE--EEDDTIHMGNAIMTFYSALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGNVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAG-TEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSM--MEKQSSMDSEGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGD--SMALYNRTRRISQTSQVS-VDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGFKDLELD-----TPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSRG----KGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCSGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRNQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSCYRILTSLYALGTS---------KSIYVERQRSALGECLAAFAGAFPVAFLETHLDKHNIYSIYNTKSSRERAALSLPTNVEDVCPNIPSLEKLMEEIVELAESG--IRYTQMPHVMEVILPMLCSYMSRWWEHGPEN----NPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAATVVSEEDHLK---AEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEP-NPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDTKS-KMS-----KAAVSDQERKKM--KRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALAKNRFSLKDTEDEVRDIIRSNIHLQGKLE-DPAIRWQMALYKDL-----------------PNRTDDTSDPEKTVERVLDIANVLFHLEQKSKRVGRRHYCLVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGA----EPPEEDEGTKRVDPLHQLILLFSRTALTEKC-KLEEDFLYMAYADIMAKSCHDEEDDDGEEE-------VKSFE--------EKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEG--------SGEKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQ--------------------DSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERSANKEE------SEKERPEEQGPRMAFFSILTVRSALFALRYNILTLMRMLSLKSLKKQMKKVKKMTVKDMVTAFFSSYWSIFMTLLHFVASVFRGFFRIICSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGDGEEGERKPLEAALPSEDLTDLKELTEESDLLSDIFGLDLKREG---GQYKLIPHNPNAGLSDLMSN--PVPMPEVQEKFQEQKAKEEE----------KEEKEETKSEPEKAEGEDGEK--------EEKAKEDKGKQKLRQLHT---HRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTSSVVEGKE------------------LPTRSSSENAKVT-SLDS------------SSHRIIAVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKK-PKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15413-1", "uniprot_id": "RYR3_HUMAN", "id": "Q15413-1", "name": "Ryanodine receptor 3", "aln": "MAEGG-EGGEDEIQFLRTEDEVVLQCIATIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYIPPDLCVCNFVLEQSLSVRALQEMLANTGENGG-----------EGAAQGGGHRTLLYGHAVLLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSVSNGN------IQVDASFMQTLWNVHPTCS--GSSIEEGYLLGGHVVRLFHGH-DECLTIPSTDQNDSQHRRIFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRAKSDTKSTAFSFRASKELKEKLDSSHK-RDIEGMGVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPLK-RKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNN----RTAAPIT-----LPIEEVLQTLQDLIAYFQPPEEEMRHEDKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNVYNSVAHFAGIAR-EESGMAWKEILNLLYKLLAALIRGNRNNCAQFSNN--LDWLISKLDRLESS--SGILEVLHCILTESPEALNLIAEGHIKSIISLLDKHGRNHKVLDILCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVAS--INQHLLRSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVMSFSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKR-DADGIRDLLGTTQFLSQASFIPCPVDTSQVILPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLP-KNYMMSNGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADSAVEKVSI---DKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAFVFEGNRGQRWHQG-SGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIE-NGFVPICCLGLSQIGRMNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPH-IEVMRIDGTMDSPPCLKVTHKTFGTQNSNA-DMIYCRLSMPVECHSS----FSHSPCLDS--------------------------------------------------------------------------------------------------------EAFQKRK----------------------------QMQEILSHT-----------------------------------------------------------TTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGD---IVASSQRSNRSNVDLEIGCLVDLAMGMLSFSANGKELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFRSEEKNPVPQCPPRLDVQTIQPVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYHTLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKERKLMMKNEYIIPITSTTRNIRLFP------DESKRHGLPGVGLRTCLKPGFRFSTPCFVVTGEDHQ---------------KQSPEIPLESLRTKALSMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDDDDVRQILLLIDPSVFG--------------------------------------------------------EHSAGTEEGAEKEEVTQVE---------------EKAVEAGEKAGKEA--PVKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTARKTKEFRSPPQEQINMLLNFQLG-----ENCPCPEEIREELYDFHEDLLLHCGVPLE-------EEEEEEEDTSWTGKLCALVYKIKGPPKPEKEQPTEE--EERCPTTLKELISQTMICWAQEDQIQDSELVRMMFNLLRRQYDSIG-ELLQALRKTYTISHTSVSDTINLLAALGQIRSLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGTE------------------KS-QIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALSLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENP------ALDLPSQ--GYKREVSTGDDEEEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAG-TEHCTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGALPPDYLDTRITAT--LEKQISVDADGNFDPKPINTMNFSLPEKLEYIVTKYAEHSHDKWACDKSQSGWKYGISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGE--ALVQQRENEKLRSVSQA---NQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFKDREKAQDLFKFLQVNGIIVSRGMKDMELD-----ASSMEKRFAYKFLKKILKYVDSAQEFIAHLEAIVSSG---KTEKSPRDQEIKFFAKVLLPLVDQYFTSHCLYFLSSPLKPLSSSGYASHKEKEMVAGLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHVTQHQFGMDLLLGDVQISCYHILCSLYSLGTG---------KNIYVERQRPALGECLASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEDMCPDIPQLEGLMKEINDLAESG--ARYTEMPHVIEVILPMLCNYLSYWWERGPEN----LPPSTGPCCTKVTSEHLSLILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLK---ADGKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSP-DADSDQLFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKS-KMSKAMQVKSGGQDQERKKT--KRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSHRDTDEEVREHLRNNLHLQEKSD-DPAVKWQLNLYKD------------------VLKSEEPFNPEKTVERVQRISAAVFHLEQ------------VEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPK---VEEEEEEETEKQPDPLHQIILYFSRNALTERS-KLEDDPLYTSYSSMMAKSCQSGEDEEEDED------KEKTFE--------EKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEG--TLIVRERGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQ--------------------DSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYVDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPEEEEE-DEDSSYVLEIAGEEEEDGSLEPASAFAMACASVKRNVTDFLKRATLKNLRKQYRNVKKMTAKELVKVLFSFFWMLFVGLFQLLFTILGGIFQILWSTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDTMEAERAEVMEPGITTELVHFIKGEKGD---TDIMSDLFGLHP---KKEGSLKHGPEVGLGDLSEIIGKDEPPTLESTVQKKRKAQA-------AEMKAANEAEGKVESEKADMEDGEK---EDKDKEEEQAEYLWTEVTKKKKRRCGQKVEKPEAFTANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEET-------------------------EDVANLWNSFND------------EEEEEAMVFFVLQESTGYMAPTLRALAIIHTIISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKA---EAASLVSWLSSIDMKYHIWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AGL3-1", "uniprot_id": "RYR3_MOUSE", "id": "A2AGL3-1", "name": "Ryanodine receptor 3", "aln": "MAEAG-EGGEDEIQFLRTEDEVVLQCIANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYIPPDLCVCNFVLEQSLSVRALQEMLANTVENGG-----------EGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGS------IQVDASFMQTLWNVHPTCS--GSSIEEGYLLGGHVVRLFHGH-DECLTIPSTDQNDSQHRRVFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLLLQDRGKSDTKSTAFSFRASKEIKEKLDSSHK-RDMEGMGVPEIKYGDSVCFVQHVASGLWVTYKAQDAKTSRLGPLK-RKVILHQEGHMDDGLTLQRCQQEESQAARIIRNTTALFSQFVSGNN----RTTAPVA-----LPTEEVLQTLQDLIAYFQPPEDEMQHEDKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSVAHFAGIVR-EESGMAWKEILNLLYKLLAALIRGNRNNCAQFSNN--LDWLISKLDRLESS--SGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSPQYKKWYFELIIDQVEPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVAS--INQHLLKSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVMSFSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKR-DADGVRDLLGTTQFLSQASFIPCPIDTSQVVLPLHLEKIRDRLAENIHELWGMNKIELGWTYGKVRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLP-KNYMMSNGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPTVEKVSI---DKIRFFRVERSYAVKSGKWYFEFEVVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSRGQRWHQG-SGYFGRTWQPGDVVGCMINLDDASMVFTLNGELLITNKGSELAFADYEIE-NGFVPICSLGLSQIGRMNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAVWFSKRLPTFVNVPKDHPH-IEVVRIDGTMDSPPCLKVTHKTFGTQNSNA-NMIYCRLSMPVECHSS----FSHSPCLDS--------------------------------------------------------------------------------------------------------EAFQKRK----------------------------QMQEILSHT-----------------------------------------------------------TTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGD---IVASSQRSSRSNVDLEIGCLLDLAMGMLSFSANGKELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNPTPQCPPRLDVQTIQPVLWSRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMQFHYHTLRLYSAVCALGNSRVASALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLANAKERKLMMKNEYIIPITSATRNIRLYP------DESKRHGLPGVGLRTCLKPGFRFSTPCFVVTSEDHQ---------------KQSPEIPLQILKTKALSMLTEAVHCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDDDDVRQILLLIDPSVFG--------------------------------------------------------EHSGETEEGVEK-EVTHAE---------------EKAVEAGEKACKEA--PVKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTARKTREFRSPPQEQINMLLNFHLG-----ENCPCPEEIREELYDFHEDLLVHCGVPLE-------EEEEEEEDTSWTGKLCALVYKIKGPPKPEKEQPTEE--EKPYPTTLKELVSQTMIRWAQENQIQDAELVRMMFNLLRRQYDSIG-ELLQALRKTYTISQASVNDTINLLAALGQIRSLLSVRMGREEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGTE------------------KS-QIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQSCPMLLARGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENP------ALDLPSQ--GYKTEVTQ-DDGEEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYLCSAVLPLLTRCAPLFSG-TEHCTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLSEYCKMPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDLDLFRMALPCLSAIAGALPPDYLDTRITAT--LEKQVSVDADGNFDPKPINTMNFSLPEKLEYIVTKYAEHSHDKWACDKSHSGWKYGISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGE--ALVQQRENEKLRCVSQT---NQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGILVSRGMKDLELD-----ASSMEKRFAYKFLKKILKYVDAAQEFIAHLEAIVSSG---KTEKSPHDQEIKFFAKVLLPLVDQYFTNHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHIAQHQFGVDLLLSDVQVSCYHILCSLYSLGTG---------KNIYVERQRPALGECLASLAAAIPVAFLEPSLNRHNPLSVFNTKTPRERSILGMPDKVEDMCPDIPQLEGLMKEINDLAESG--ARYTEMPHVIEVILPMLCNYLSYWWERGPEN----LPPSTGPCCTKVTSEHLSLILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLK---TDGKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSP-DPDSDQLFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKS-KMS-----KSGGQDQERKKT--KRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSCRDTDEEVKEHLRNNLHLQEKSD-DPAVKWQLNLYKD------------------VLRNDEPSNPEKTVERVQSISAALFHLEQ------------VEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEAHFFEEKLVQDLAKSPR---VEDEEEEETERQPDPLHQIILHFSRNALTERS-KLEDDPLYTSYSSMMAKSCQSGEDEEEEED------KEKTFE--------EKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEG--TLIVRERGEKVLQNDEFTQDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQ--------------------DSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISRKEFQKAMEGLKQYTQSEIDFLLSCTEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKSLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSTDRPEEEEEEDEDSAYSIETEGEEEEK-SFESASAFTMACVSVKRNVTKFLKRATLKNLRKQYRNVKKMSAKELVKVFFSFFWMLFVGLFQLLFTIFGGIFQILWNTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDVIETDRAEVTEPGVTTELVHFVKGEAGD---TDIMSDLFGIHS---KKEGGLKQGPEVGLGDLSEIIGKDEPPTLESTVRKKRKAQA-------AEMKAVHEAEGKAESEKADMEDREK---EDKIKEEGQTDYLWADVTVKKTRRRGQKAEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEET-------------------------EDVANLWNSFND------------DDEEEAMVFFVLQESTGYMAPTLRALAIVHTIISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEEAKA---EAASLVSWLSSIDMKYHIWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3ALN1-1", "uniprot_id": "A0A8M3ALN1_DANRE", "id": "A0A8M3ALN1-1", "name": "", "aln": "MAEG---EGEDEVQFLRTEDEVVLQCVAAIQKENRKFCLSAEGLGNRLCYLEPTSEAKYVPPDLCICNFVLEQSLSVRALQEMLAGQSGEGNP-------DHEQWAAQGGGHRTLLYGHAILLRHSFSGMYLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGS------IQVDASFMQTLWNVQPTCS--RSSVAVGYLLGGQVMRLFHGH-DESLTIPGYEQSQEQQRVVNYEAGKGGSKARSLWRLEPLRISWSGSHMRWGQPFRLRHLSTGHYLGQTEDQGLILLDREKSDTAATAFCFRPS---KEKIESGPK-RDIDGMGIAEIKYGDSVCFIMHVSTGLWLSYQAPDAKSSRLGPLK-RRAFLSPEGHMDDGLILQLCQHEESRAARIIRNTTHLFTQFIRGLDSLSGEKASEVT-----LPVSEVLETLNDLIVYFQQPDSELEHEEKQRQLRSLIKRQDLFKEEGMLTLLSHCIDRLNVYNSAAEFEELAG-EEAGEAWKDILNLLYELLAALIKGNRTNCTQFSRK--LDWLVSKLERLESS--SGILEVLHCILNESPESLNIIQKAHIKSIISLLYKHGRNYKILDVLCSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLVNDVQSMRPNIFLGMSEGSAQYRKWYFELIIDQVDHFVTSEPTHLRVGWATTKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWAGRIPRAVAS--INQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNVDGFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKR-DLEGVRDLLGTTEFLSQASFIPVPVDTSQIVLPPHLENVRDKLAENIHELWGMNKIELGWMYGKVRDDNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVAQVNINAEDDLKKMKLP-KNYMMANGYKPTPLDLSEIKLNPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNRRNPRLVPYALLDERTKKSNRDSLREAIRTLVGYGYFIDPPDQETAH-QVEKEGI---ESIRLFRVEKTYAVKTGKWYFEFEAITGGDMRVGWARPGCRPDIELGMDDQSFVFDGHRGRRVHMG-SHFFARSWNKGDVVGCLINMEDKSMIFTLNGEILITNKGSELCFADFETE-DGFIPVCSLGLSQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPEDHPH-IEVTRIDGTVDTPPCLKVTHKTFGTQTSND-DMICCRLSMPVEFHAGPRKITDINEVIAE--------------------------------------------------------------------------------------------------------DQRAKKD----------------------------DGGKVDYGS-----------------------------------------------------------ITKYFYSVKVFAGQDPSSVWLGWVTPDYHYYSKHFSLDTVRTVTVTLGDERGRVHESVRRSNCYMVCAGD---VASSS--TSRSNVDLEIGCSIDLASGLVSFTANGRELPTAYQVEPNTKLFPAVFVQPTSPNLFQIEFPKIPDAMPLSSAIFKSLLKNPEPQCPPRLDVQTIVSVLWSRMPNTFLTVETARVSERHGWVVQCLEPLQMMAVHIPEENRCIDIMELSENEDLRKFHYHTLKLFCSLCALGNTRVAHSLCSHLGQSQFLYIIDNQYLTGQLREGFYNVLISIHLETAKEARLMMNNEFIIPVTDETRSIRLFP------DDSKRHSLPGVGLSTSLTPRLNFTPPCFITTKRETP---------------LYSPQIPLAIMKEKAISMLTEAVQGGGAHIRDPVGGSVEYQFVPILKLIGTLLIMGAMTSEEVKTILLLIEPIVFGDS--------------------------------------------------KEEEEQTAVVEQGAEKEEATSNE---------------EKAVEAGEEEGKESKQPPKGLLETSLPESVKRQMCELLHYFCDCELKQRIEAIVAFSDDFVSKLQFNQKFRYNELMLALNMSAAVTAKKTREFRSPPQEQINMLLNFSAG-----DDCTCPEELQEELQTFHNDLRLHCGIPME-------EEEEEQ-DTSLKGRLMAIIYKIKGRPQKTEEEPTKQ--EQATPTNLKELISQTMVSWAQEYKIQDPELVRSMFSLLRRQYDGIG-ELLRALRKSYTISDKSVGDAINLLASLGQIRSLLSVRMGEEEGQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGD------------------KNKEIAFPKVVASCCRFLCYFCRISRQNQKSMFDHLSYLLENSSVGLACPEMRGSTPLDVAASSVMDNNSLALALEEPDLEKVVTYLAACGLQNCPMLIARGYPDIGWNPIEGERYLSFLRFAVFVNGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDP------ALDLPT----LPEGVAPTVVEDEEEVAHMGNSIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPIKDLVGIISIPLKMPVVNKDGTVTEPDMNASFCPEHKAPMVLFLDRVYGVDDQSFLLHLLEVGFLPDLRASASLNSEVLRSTETALAMNRYIGSAVLPLLTRCAHLFAH-TEHYATLVDSTLHTIYRLSKGRSLTKAQRDAIDECLLAICMHLRPSMLQQLLRRLVFDVPQLTEYCKMPIKLLTNHYEQNWKYYCLPTGLGSYGMASEEELHLTKKLFWGLFDALSQKKYDSELFKMAMPCLSAIAGAIPPDYVDSSPGSA--LVKQASVDAQGNFDPQPINTANISLPEKLDYIASKFAEHSHEKWSSEKIALGWTVGDKVDDKAKTHPLLKPYKALSEKERETYRYPVKETLKSMLAMGWNIERTKEGE--AMFQQRETEKQRKISES---TQG-DFIPAPQDLENVVLSRELQAMVETVAENYHNIWAKKKKKELDSKGGGSHPLLVPYDTLTAKEKYRDRDKAQELFKFLQVNGYAISRGLKDMEQD-----SSSMEKRFAYKFLKRLLSYVDSAQEFIAHLEAMATSG---KTDKSPHDQEIKFFAKILLPLIDQYFKNHCLYFLSSPNINLSSSGYASNKEKEMITSLFCKLAALVRHRISLFGSDSATMVSCLHILSRTLDFRTVMKSGSELVKAGVRTFFENAAEDLEKTLENLKLGKLGQSRTQMKGVTQIISYTSVALLPMLTVLFQHVTQHQFGAELLLDDIQLSCYRILTSLYSLGTG---------KNIYVEKQLPVLGECLSSLVGAMPVAFLEANLNMHNPQSVFNTKTPRERAILSMPDTVDEMCPEMPHLDGLMKEIGDISESG--ARYTEMPQIIEVVLPMLCNYLSYWWAKGPEN----SPDGAN-CCTSVTSEHLSLILGNILKILNNNLGIENAPWMKRLAVYTQPIISRASADLLRAHFLPTLEKLKKKTVKVVSEEEMLR---AESRADTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRSTWLKEP-DSDSTELFKMVSEIFILWCKSHNFKREEQNFVVQNEINNLAFLAGDSKS-KMS-----KSGGQDQERRGK--KRRGELYSVQTSLIVAAHKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKDYLRKNLHLQEKSE-DPAVQWQINLYKDI-----------------VLKSEGPPDPEQNVERIQAISSAVYHLDQ------------VELPLRNKKILFQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLSGYQRLWIETEEYSFEEKLVQDLAKTPMT-VVEEEEEEEAEVQPDPLHQLILHFSHNALTERS-FLEEDPLYIAYADMMAKSCAENEEEEEEEEG-----KEKTFE--------EKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTGTLKLGISVLNGGNVLVQQKMLDYLKEKRDAGFFKSLSALMMSCSILDLNAFERQNKAESLGMVTEEG--SISVKGRGSKVLQNDDFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEAGQHNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQ--------------------DSSQITLLKELMDLQKDMVVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTSSDNFKEYDPDCKGMISKRDFQKSMESQKQYTQSEIEFLLSCVEADENDMFNYSDFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLSTFLDLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGESEKMEMFVNFCEDTIFEMQLASQISEPDPTERPEEEEE---EELHSLLEGLSEEEDASLESASAFTAACASVKKSMSNFRQMLTFKSMKKQMKKFRKLTIREMITGFFSFFWMLFTGFFKGIFGIIFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLEAEKAEISEMVVSADMVQMTGAGGGEKLEPDVIMDLLNPAV---KKEG--KHGAEPGLGDVCEILTETSAP-----VEKKKSQKV-------AAEKPESEPE------KADTENQEK---EDKTKEEAPEEPAAEKPAPKVKR--GSSKDESPAFMASFFAGLEVYKTKMLNYLARNFYNLRFLALFVAFAINFILLFYKVTGDFDDEEE-------------------------EEGSWGGEEEEA------------DEDEGGMEYFILQESTGYMAPTLTFLAVLHTVISLLCVFGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFDPTEEAVV---KEASLLSWLSSIDTKYHVWKMGVVMTDNSFLYLIWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LMY4-1", "uniprot_id": "RYR1_RAT", "id": "F1LMY4-1", "name": "Ryanodine receptor 1", "aln": "MGDGG-GEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEAGVE------------SSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGE------LQVDASFMQTLWNMNPICS--CCE--EGFVTGGHVLRLFHGHMDECLTISPSDS-DDQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDASKAHTKATSFCFRIS---KEKLDVAPK-RDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLK-KKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDSFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAG-EEAAESWKEIVNLLYELLASLIRGNRTNCALFSTN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS--PGQHLLGPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRR-EGPRGPHLVGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLP-KTYMMNNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPS-QVDSQSRG---DRARIFRAEKSYAVQSGRWYFEFEAVTTGR-ELGWARPELRPDVELGADDLAYVFNGHRGQRWHLG-SEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIG-DGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLEHPH-YEVARMDGTVDTPPCLRLTHRTWGSQNSLV-EMLFLRLSLPVQFHQHFRCTAGATPLASPGLQPPA----------------------------------------EDEARAAEPDTDYENLRRSAGGWGEAEAGKDGTAKEGTPGGAAQPGVEAQPARAENEKDATTEKN----------------------------KKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPA-----------------------DNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGD---FVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVVQFDLRPGANIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLHVDTRRAGERLGWAVQCQEPLMMMALHIPEENSEPYIHLKRAQLDPRDLRDYRDTKFDSESSD-SDQTPQPGCYHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTEETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGAAE---------APARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVKQILKMIEPEVFTEE--------------------------------------------------EEVEEEEEE-EEEDEEEKEEDEE-------EEAHEKEDEEKEEAEEAAEEEKEELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQSNQRGRYGLLMKAFTMSAAETARRTREFRSPPQEQINMLLQFKNGA--DEEDCPLPEEIREDLVNFHQDLLAHCGIQLEG------EEEEPEEESTLGSRLMSLLEKVRLVKKKEEKPEEEPAAEEHKPQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLG-ELLRALPRAYTISLSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------ESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDP------ARDGPGVRRDRRREHFGEE-PPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSR-RWALALTRYLC-AVLPLITKCAPLLRG-TEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCLCAIAGALPPDYVDASYSSK--TEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYAHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGE-EEKTEKKKTRKISQTAQT--YDPREGYNPQPPDLSVVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRHGKDMELD-----TSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSG---RVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTT---------RNPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMAEIGGLAESG--ARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIGRLRKRAGKVVAEEEQLR---LEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRSAWPRLPPSPSSSFSLPSPSELGRWLMKDHGHQLYEESFTVPLILDNAAFPLARNQSRAIGCAGVVRSGGSDQERTKK--KRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGV-----------------PGREEDADDPEKIVRRVQEVSAVLYHLDQ------------TEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASWILTEDHSFEDRMIDDLSKAGE---QEEEEEEVEEKKPDPLHQLVLHFSRTALTEKS-KLDEDYLYMAYADIMAKSCHLEEGGENVEEGGEEEEVEVSFE--------EKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCRWPHKTLSQREGQEERVMKVQTSGTLVIINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQ--------------------DSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILDYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGEP-EEDDDE-------GAEEAEEGAAGPDGSGSAAAAGVWTWLATAAGRTLRGLSYRSLRRRVRRLRRLTAREAATAVAVLLWAMVARAGGAGAGAAAGVLRLLWGSLFGGGLVDSAKKVTVTELLAGMPDPTGDEVHGQQPSGAGSDAEGEGQGEGEGDAAEGVGDEEVAADQAGTGGADRTVAVADGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVD--GEEEEPQPEPEPEPEP--EPEKADTENGEK-----E-VPEPPPEPPKK--APPPPP--PKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDD-------------------IEGSGAGDMSGAGSGDGS-GWGSRASEEVEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNERKP--DPPPGLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZQ0-1", "uniprot_id": "RYR1_MOUSE", "id": "E9PZQ0-1", "name": "Ryanodine receptor 1", "aln": "MGDGG-GEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEAGVE------------SSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGE------LQVDASFMQTLWNMNPICS--GCE--EGFVTGGHVLRLFHGHMDECLTISPSDS-DDQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLGLTEDQGLVVVDASKAHTKATSFCFRIS---KEKLDVAPK-RDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLK-KKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDSFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAG-EEAAESWKEIVNLLYELLASLIRGNRTNCALFSTN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS--PGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRR-EGPRGPHLVGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLP-KTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPS-QVDSQSRG---DRARIFRAEKSYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADDLAYVFNGHRGQRWHLG-SEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEIG-DGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLEHPH-YEVARMDGTVDTPPCLRLTHRTWGSQNSLV-EMLFLRLSLPVQFHQHFRCTAGATPLASPGLQPPA----------------------------------------EDEARAAEPDTDYENLRRSAGGWGEAEGGKDGTAKEGTPGGTAQAGVEAQPARAENEKDATTEKN----------------------------KKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPA-----------------------DNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGD---FVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVVQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVDTRRAGERLGWAVQCQEPLMMMALHIPEENRCMDILELSERLDLQRFHSHTLSLYRSVCALGNNRVAHALCSHVDQAQLLHALEDARLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGATE---------APARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVKQILKMIEPEVFREE--------------------------------------------------EEVEEEGEE-EEEDEEEKEEDEE-------EEAHEKEDEEKEEAEDAAEEEKEELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAECYVDKMQGNQRGRYGLLMKAFTMSAAETARRTREFRSPPQEQINMLLHFKNGA--DEEECPLPEEIRQELVNFHQDLLAHCGIQLEG------EEEEPEEESTLGSRLMSLLEKVKLVKKTEEKPEEEPAPEEHKPQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLG-ELLRALPRAYTISVSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------ESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDP------ARDGPGVRRDRRREHFGEE-PPEENRVHLGHAIMSFYAALIDLLGRCAPETHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAG-TEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCLCAIAGALPPDYVDASYSSK--TEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGE-EEKTEKKKTRKISQTAQT--YDPREGYNPQPPDLSVVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELD-----TSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSG---RVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTT---------RNPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMAEIGGLAESG--ARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIGRLRKRAGKVVAEEEQLR---LEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEP-NPNAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKS-KMAKAGDVQSGGSDQERTKK--KRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGV-----------------PGREEDADDPEKIVRRVQEVSAVLYHLDQ------------TEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASWILTEDHSFEDRMIDDLSKAGE---QEEEEEEVEEKKPDPLHQLVLHFSRTALTEKS-KLDEDYLYMAYADIMAKSCHLEEGGENGEEGGEEEEVEVSFE--------EKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDG--TVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQ--------------------DSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMEMFVSFCEDTIFEMQIAAQISEPEGEP-EEDEDE-------GAEEAEEGAAGSDGSGSAAAAGVWVWLAATAGRTLRGLSYRSLRRRVRRLRRLTAREAATAVAALLWALVTRAGGAGAGAAAGALRLLWGSLFGGGLVDSAKKVTVTELLAGMPDPTGDEVHGQQPSGAGSDAEGEGEGEGEGDAADGAGDEEAAADQAGTGGADGAVAVADGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVD--GEEEEPPPEPEPEPEP--EPEKADTENGEK-----E-VPEPPPEPPKK--TPPPPP--PKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDD-------------------IEGSGAGDMSGAGSGDGS-GWGSRAGEEVEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNERKP--DPPPGLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21817-1", "uniprot_id": "RYR1_HUMAN", "id": "P21817-1", "name": "Ryanodine receptor 1", "aln": "MGD---AEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQSLSVRALQEMLANTVEAGVE------------SSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDIILVSVSSERYLHLSTASGE------LQVDASFMQTLWNMNPICS--RCE--EGFVTGGHVLRLFHGHMDECLTISPADS-DDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRVRHVTTGQYLALTEDQGLVVVDASKAHTKATSFCFRIS---KEKLDVAPK-RDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLK-KKAMLHQEGHMDDALSLTRCQQEESQAARMIHSTNGLYNQFIKSLDSFSGKPRGSGPPAGTALPIEGVILSLQDLIIYFEPPSEDLQHEEKQSKLRSLRNRQSLFQEEGMLSMVLNCIDRLNVYTTAAHFAEFAG-EEAAESWKEIVNLLYELLASLIRGNRSNCALFSTN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSKWYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS--PGQHLLAPEDVISCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRR-EGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLP-KTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVGQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPS-QVENQSRC---DRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLG-SEPFGRPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIG-DGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKGLPQFEPVPLEHPH-YEVSRVDGTVDTPPCLRLTHRTWGSQNSLV-EMLFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPA----------------------------------------EDEARAAEPDPDYENLRRSAGGWSEAENGKEGTAKEGAPGGTPQAGGEAQPARAENEKDATTEKN----------------------------KKRGFLFKAKKVAMMTQPPATPTLPRLPHDVVPA-----------------------DNRDDPEIILNTTTYYYSVRVFAGQEPSCVWAGWVTPDYHQHDMSFDLSKVRVVTVTMGDEQGNVHSSLKCSNCYMVWGGD---FVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFQSERKNPAPQCPPRLEMQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSTENGHPRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGAAE---------APARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEE--------------------------------------------------EEEEDEEEEGEEEDEEEKEEDEE-------ETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYGLLIKAFSMTAAETARRTREFRSPPQEQINMLLQFKDGT--DEEDCPLPEEIRQDLLDFHQDLLAHCGIQLDG------EEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSLQELVSHMVVRWAQEDFVQSPELVRAMFSLLHRQYDGLG-ELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------ESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLVAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDP------ARDGPGIRRDRRREHFGEE-PPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLEDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAG-TEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMSLCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDPELYRMAMPCLCAIAGALPPDYVDASYSSK--AEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGE-EEKTEKKKTRKISQSAQT--YDPREGYNPQPPDLSAVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELD-----SSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSG---RVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTT---------KNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMADIGGLAESG--ARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPSALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLQSHFIPTIGRLRKRAGKVVSEEEQLR---LEAKAEAQEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAQWLTEP-NPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKS-KMAKAGDIQSGGSDQERTKK--KRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLITLAKTRYALKDTDEEVREFLHNNLHLQGKVEGSPSLRWQMALYRGV-----------------PGREEDADDPEKIVRRVQEVSAVLYYLDQ------------TEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGE---QEEEEEEVEEKKPDPLHQLVLHFSRTALTEKS-KLDEDYLYMAYADIMAKSCHLEEGGENGE---AEEEVEVSFE--------EKQMEKQRLLYQQARLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDG--TVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQ--------------------DSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFSGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLHNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPEGEP-ETDEDEGAGAAEAGAEGAEEGAAGLEGTAATAAAGATARVVAAAGRALRGLSYRSLRRRVRRLRRLTAREAATAVAALLWAAVTRAGAAGAGAAAGALGLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGEGASEGAGDAAEGAGDEEEAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVD--GVEEELPPEPEPEPEPELEPEKADAENGEK-----EEVPEPTPEPPKKQ-APPSPP--PKKEEAGG----EFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDD-------------------MEGSAAGDVSGAGSGGSS-GWGLGAGEEAEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAELLGMDLATLEITAHNERKP--NPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YTI2-1", "uniprot_id": "A0A8M6YTI2_DANRE", "id": "A0A8M6YTI2-1", "name": "Ryanodine receptor 1", "aln": "MAEG--EGGDEEIQFLRTEDQVVLQCTATVLKEQIKLCLSCEGFGNRLCFLETTSNAQNVPPDLAICSFVLEQSLSVRALQEMLANTVDMTEAV------DLDKWSSQGGGHRTLLYGHAILLRHYHSSMYLSCLTTSRSLTDKLAFDVGLQLDATGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYASGD------LMVDASFMQTLWNMNPVCS--GCELAEGYLTGGHVLRLFHGHMDECLAISTPDQGEEERKIAQYEGGAVCSQARSLWRLEPLRIGWSGSHMKWGQAFRVRHITTGRYLCLDDEKGLMVLDPEKANTKQSAFSFRAS---KEKVEGEKKKRDVEGMGIPEIKYGESMCFMQHISTGLWLTYAALDAKAARLGTMK-RRVMLHQEGHMDDALTCSRSQTEESQAARMIYSTTGLFTQFIKGLDSLSGKNKSPGP---VSLPLDGVILSLQDLIHYFRPPEEELEHEEKQTKLRSLRNRQNLFQEEGMITIVLECIDRLNVYNTAAHFSEFAG-EEAAESWKEIVNLLYELLASLIRGNRSNCALFCDN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLRSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIVNYASSVRPNIFLGTCEGSTQYKKWYFEVMVDYVESFVTAQATHLRVGWAMTEGFSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGHVSRQVAS--PNQHALAADDVVSCCLDLSVPSISFRINGHPVQGMFENFNLDGLFFPAISFSAGVKARFLLGGRHGDFKFLPPPGYAPCYEALLPKDRMRIEPIKEYKH-DFEGVRNLLGPTQSLTHTSFTPCPVDTAQIVLPPHLERIREKLAENIHELWAVTRIEQGWTYGVFRDDNKKLHPCLVDFQSLPEPERNYNLQMSGETLKTLLALGCHVGMGDEKAEENLRKIKLP-KTYVMSSGYKPAPLDLNHVKLTPNQNQLVEKLAENGHNVWARDRVRQGWTYSIVQDIVNKRNPRLVPYNLLDERTKKTNRDSVNNAVRTLIGYGYNIEPPDQESSGHGVEDVHG---DKVRIFRAEKQYGVTSGKWYFEFEAVTTGEMRVGWARPNVRSDVELGSDELAYVFNGNRAQRWHIG-NDPFGRQWQSGDVVGCMIDLIEMNIMFTLNGEMLISDSGSEMAFKDIEIG-DGFIPVCTLGLSQVGRINLGQNVSSLRYFAICGLQEGFEPFAINMKRDITMWFSKSLPQFVPVPTDHNH-IEVSRVDGTVDSAPCIKITHKTFGSQNANT-DMLFFRLSMPVEFHLTFKVPAGTTPLTRALTIP------------------------------------------EEEVLEVDPDSDYEVLKKSASRKEQEEKEKEPSVPKDIPG----------VKE--NDKDTASEKG----------------------------KKKGFLFKAKKAAMITPPPPPPLMPRLIEDVVPD-----------------------D-RDDVDIILNTTTYYYSVRIFAGQEPSEVWVGWVTPDFHMYDLNFDLSKVRTVTVTVGDDKGNIHDSIKRSNCYMVWGGE---FSS-SQQ-KFSQEDLVIGCLVDLATGLLNFTANGKEINTFYQVEPNTKLFPAVFVLPSSQNMLQLELGKLKNIMPLSAAMFRSERKNPVPQCPPRLDVQMLTPVIWSRMPNHFLNPVVGRVSERHGWMVECTEPLTMMALHIPEENRCIDILELSEQHDLLQFHYHTLMLYCAVCALGNNRVAHALCSHVDESQLFYAIENTYLPGPLRSGYYDLLISIHLESAKRNRLGTNREFIVPMTSETLSITLFP------DAEAAHDLPGVGLTTCLRPKLHFSPINFVGTDPDL---------------YTLSPIIPLQNLKTQALSMLTEAVFDGSQAMRDPVGGSVEFHFVPILKLISTLLIMGIFNNEDVKHILKMIDPSVFGKK-----EEAEEPAEEAAPKEEGEEVKEKEETAEG--EEEAVDEGVGEEEEEELKELKKEEGEEGEEVEKAVEEEDGEKVDGEKAEE-EKEAEEVGEEAKEEEEEAPEEGLLQMKMPESVKLQMCTLLQYFCDCELRHRVEAIMAYSDNFVGQIQSNQRERYNELMRAFTMSAAETARRTREFRSPPQEQIFLLTNFKHNP--EEEDCPVPDEVRETHNNFHNDLLNHCGVHIEE------EVEEEEVDTSLRGRLLTLVDKVKSLKQKKEEEEPEP-EEEPKPSTLQELISHTMIHWAQEAFIQNPELVRLMFSLLHRQYDALG-ELIRALPKAYAISAVSVQDTMEMLECLGQIRSLLIVQMGPEEERLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGG-----------------DSKEIRFPQMVTNCCRFLCYFCRISRQNQRSMFDHLSYLLQNSGIGLG---MRGSTPLDVAAASCIDNNELALALQEQDLEMVVTYLAGCGLRMCPMLLSKGYPDIGWNPGGGERYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRGEGGAGLLAAIEEAIKISEDP------ARDGPTPKKDRRF-MFGGEDQHEENRLHLGNAIMSFYSALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLPVQIPTFGKDGQIVEPKMSASFVPDHKASMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRASASLDTVAFSTTEMALALNRYLCSAVLPLLTKCAPLFAG-TDHRAIMIDSMLHTIYRLSRGRALTKAQRDVIEDCLMSLVKYLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWANFGVTSEEELHLSRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASYSSM--TEKKASVDAEGNFDPKPVETTNTIIPERLDAFINKYAEHTHDKWAFEKIQNNWTYGEVLDENAKTHPMLRPYKTFSEKDKEIYRWPIKESIKAMLAWEWTLEKARDGETEVKTEVKATRKISQTAQAT-YDPSQGYSPQPVDLIGMALSRELQSMAEQLAENYHNTWGRKKKMELQAKGGGTHPLLVPYDTLTAKEKARDREKAQDLLKFLQLNGYAVTRGLKDMEQE-----ISSIEKRFAYGFLQKLLKWMEIAQEFIAHLEAVVSSG---RVEKSPHEQEIKFFAKILLPLINQYFKNHCLYFLSTPAKVLGSGGHASNKEKEMIASIFCKLAGLVRHRVSLFGTDASAVVNCLHILSRSLDARTVMKSGPEIVKAGLRSFFESAADDIEKMVENLKLGKVSTKNQ-VKGVSQNISYTTTALLPVLTSLFDHIAQHQFGDDVMLDDLQISCYRIMCSIYSLGTV---------KTPHAENQRPALGECLAHLAAAMPVAFLEPNLNEFNSYSVYTTKTPRERTILGLPSQVQELCLDIPELDVLMKEIGHLAESG--ARYTEMPHVIEITLPMLCNYLPRWWERGPEN----FPEQEGCLCTDVTSEQLNQLLGSIMKIVVNNLGIDEASWMKRLAVFAQPIVSRAKPEMLKSHFIPTMEKLKKRSGKVVAEEEQLR---MEGKTEVDSEGGTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTCP-DPDAEDLFRMVGEVFIFWSKSHNFKREEQNFVVMNEINNMSFLTADSKS-KMSKAGDGEGGGSDDDRTKK--KRRGDRYSVQTSLIVAALKKLLPIGLNMCSPADQELINLAKIRYSLKDTDEEVREFLQNNLHLQGKVE-DPSMRWQMALYKET-----------------SGKAEDADAPEKVVKRVQEVSAVLYHLEL------------TEHPYKSKKMVWHKLLSKQRRRAVVACFRMTPLYNIPRHRASNMFLDGYKRNWLENEGYSFEDKMIDDLSKALE---QEEEEEEETESKPDPLHQLILHFSRTALTEKL-KLEVDHLYMSYADIMAKSCHIGEEDEGGEE----GGVEPSFEVR--QTEMEKEMEKQRLLYQQSRLHDRGAAEMVLQMISACKGETGVMVSSTLKLGISILNGGNSDVQQRMLDYLKDKKDVGFFLSLQALMQTCSVLDLNAFERQNKAEGLGMVSEEG--TNMKLQREEKVMADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINIIICTVDFLLRLQESISDFYWYYSGKDIIDEPGKRNFSKAMTVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQMHPDQGLRDGDHFWSRTHSEDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFSKAMDSQKQYTPSEIQFLLSCSEADENEMINFEEFANRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLQNFLEQAESVLNYFRPFLGRIEIMGASKRIERIYFEISEANRNQWEMPQVRESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMNIASQISEQEEEVIEDEDEEEEEESGGGGGGEGEGEEGNGEEAPPESSSAFADFIKSIVNFLSLFTFRNLRRRYRKIRKMTIKDMIVGLVMFLYTVLFGILHFIYSVCKGFFLLIWNTLFGGGLVEGAKKMTLTEILTNMPDPTQDEVHGDLPPEPGARKVQEAGGAGEGEEGAGGGEEEAEEGEEDEDGRAG-----------FGPHGGLGDMGETEPEEPPTPEGSPLLKRKLVSEEGVEGEVVVEEEKVEEEPAPEPEKADAENGEK-EKEAEPETEDKQEEEQAEIAKAKAK--AKKGKKEEEVGFELWNELEIQRIKFMNYLSRNFYNLRFLALFIAFALNFILLFYKVSDRLPGEEEEFEGSAMFEGSGAFEGSAVFEGSAVFEGSGVFEGSGE-AEGSGMEENGEEDEENGFVYYFLEESTGYMEPAMAFFSILHTIISFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYVTEQPEDDDIKGQWDRLVLNTPSFPNNYWDKFVKRKVLEKYGDIYGRERIAELLGMDLASLDVSAMTHEKK-RQPDPSMFTWLTSIDIKYQIWKFGVVFTDNTFLYLVWYTVMSLLGHFNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLLMTVGLLAVVVYLYTVVAFNFFRKFYNMSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDSTPHGFETHTMEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U3K9-1", "uniprot_id": "A0AB32U3K9_DANRE", "id": "A0AB32U3K9-1", "name": "", "aln": "MAEG--AEGEEEIQFLRTDDQVVLQCTATILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTTELNEAV------DLDKWSSQGGGHRTLLYGHAILLRHTHSGMYLSCLTTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDIILVSVSSERYLHLSYASGD------LMVDASFMQTLWNMNPVCS--GCELAEGFLTGGHVLRLFHGHMDECLTIPGAEQGDDQRRNAHYEGGAVCSHARSLWRLEPLRIGWSGSHMKWGQSFRVRHITTGRYLCLDEEKGLLIVDPEKANTKQSAFCFRAS---KEKTEVAQK-RDVEGMGIPEIKYGESMCFVQHVATSLWLTYASVDAKSARLGPLK-RKAILHQEGHMDDALTVARSQTAESQAARMIYNTAGLFTQFIKGLDSLSGKSKSPGPS--PSLPLDAIVLSLQDLIFYFRPPEEELEHEEKQTKLRSLRNRQNLFQEEGMITLVLDCVDRLNVYNTSAHFSEFAG-EDAAESWKEIVNLFYELLASLIRGNRANCALFCDN--LDWLVSKLDRLEAS--SGILEVLYCILIESPEVLNIIQENHIKSIIALLDKHGRNHKVLDVLCSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIINYVTSMRPNIFLGTCEGSTQYKKWYYELIVDHVESFLTAHPFHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLHSYGFDGLNLWTGRVPRQVTS--PSQHILSAEDVVSCCLDLSVPSISFRINGHPVQGMFENFNLDGLFFPVVSFSAGIKVRFLLGGRQGDFKFLPPPGYAPCYEAVLPKDRLRIEPIKEYKH-DNDGVRNLLGPTQSLSHTAFTPCPVDTVQIVLPPHLERIREKLAENSHELWAVTRIEQGWTYGLFRDDNKKLHPCLVDFQSLPDPEKSYNLAMSGETLKTLLALGCHVGMGDEKAEENLKKIKLP-KTYMQCNGYKPAPLDLNHVKLTPNQNTLVERLAENGHNVWARDRVRQGWTYSIIQDIVNKRNPRLVPYILLDEKTKKTNRDTVCAAVRTLIGYGYNIEPPDQESSGHGGGNGRS---DKIRVFRAEKSYAVTQGKWYFEFEAVTVGEMRVGWARPSVHADRELGSDDLAYVFNGFKSQRWHIG-NEPFGRQWQSGDVVGCMIDLTEQNIMFTLNGEMLISDSGSEMAFKDIEIG-EGFIPVCSLGMSQVGRINLGQNVSSLRYFTICGLQEGFEPFAINMKRDITMWFSKSLPQFVPVPTDHPH-IEVSRVDGTVESAPCLKLTHRTFGSQNANT-DLLFFRLSMPIEFHETFKVPVGASPLTRTLTIP------------------------------------------EDETLEVDPESEFELLKKSATRKEQDEKEKEPSVPKELPG----------SKESENEKDTTTEKS----------------------------KKRGFFSKAKKAAFIAPPPVVPTMPRLMEDVVPD-----------------------D-RDDVEIISNTTTYYYSVRVFAGQEPSGVWVGWVTPDYHLYDLHFDLCKVRNVTVTVGDDKGNIHDSVKRSNCYMVWGGE---FSS-SQQTRISQEDFVIGCLVDLDTGLMTFTANGKEINTFYQVEPNTKLFPAVFCLPSSQNMLQVELGKLKNIMPISAAMFRSDCKNPVPQCPPRLDLQMLTPVIWSRMPNHFLSPETGRVSERQGWKVQCMEPLVMMALHIPEENRCIDILELSERTDLMKFHYHTLKLYGSVCALGNNRVAHALCSHVDESQLFYAIENTYLPGPIRSGYYDLLISMHLESAKRNRLMTNKEFIVPMTDETRSITLYS------DAEKAHALPGVGLTTCLRPKLHFAPTGFVGTNADL---------------YTLSPMLPLQMLKDHALSMLTEAVQDGGQAIRDPVGGSVEYHFVPILKLISTLLIMGVFDDDDVKHILKLIEPSVFSSNSETPAEETGDPEQQLVCKEEGAEVKEQEEPADGGNDGELLDEGMGEEEELEEEEEEEDE-EYEEEVKKEEDEHAAEKTDREKTTDGETEKETGAAEAEVREEEDVGEGLLHMKLPESVKLQMCTLLQYFCDCELRHRVEAIIAFSDKFVNQVQTNQRQRYNELMQAFTMSAAETARKTREFRSPPQEQVNMLMNFKNCP--EEEDCPVPEDVRNGLLTFHHDLLAHCGVHIEE------EEQEEEVDTSLSGRLRRLVEKVKSLR-KKPEAEPEP-EEDKKPSTLQELISHTMIYWAQESFIQNPELVRLMFSLLHRQYDALG-ELIRALPKAYIINAVSIQDTMELLECLGQIRSLLIVQMGPEEERLMIQSIGNIMSNRVFYQHPNLMRALGMHETVMEVMVNVLGGG------------------DSKEIRFPRMVTNCCRFLCYFCRISRQNQRSMFDHLGYLLQNSGIGLG---MRGSTPLDVAAASCIDNNELALALQEQDLEMVVKYLAGCGLQSCPMLLSKGYPDIGWNPVGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAIEEAIKISEDP------ARDGPTVKKDRRFPMFGGEEQHEENRVHLGNAIMSFYSALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLSVQIPAFGKDNSIIEPKMSASFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTAAFSTTEMALALNRYLCSAVLPLITKCAPLFAG-TDHRAIMIDSMLHTIYRLSRGRSLTKAQRDVIEECLMSLCRYLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWANFGVSSEEELHLTRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASYSSK--TEKKASVDAEGNFDPKPVDTTNTIIPEKLDGFINRYAEYTHDRWAFEKIQNNWTFGEVMDENAKTHPMLRPYKTFSEKDKEIYRWPIKESIKAMIAWEWTLDKARDGE-DEKVEKKTARKISQTAQAT-YDPSHGYSPQPIDISGMTLSRELQSMAEQLAENYHNTWGRKKKMELQAKGGGTHPLLVPYDTLTAKEKARDREKAYELLKFLQLNGYAVTRGLKDMESD-----ISSIEKRFAYGFLQKLLKWMDIAQEFIAHLEAVVSSG---RVEKSPHEQEIKFFAKILLPLINQYFKNHCLYFLSTPAKILGSGGHASNKEKEMIASIFCKMSALVRHRVFLFGTDAPAIVNCLHILARSLDARTVMKSGPEIVKAGLRLFFESAADDIEKMVENLKLGKVSKGNQPVKGVSQNINYTTTALLPVLTSLFDHIAQHQFGDDVILDDLQMSCYRIMCSIYSLGTV---------KTPHAERHRPALGECLAHLAAAMPVAYLEPHLNEYNAFSVYTTKTPRERAILGLPNQVQELCLDIPELDVLLKEIGDLAESG--ARYTEMPHVIEVTLPMLCNYLPRWWERGLEN----FPDLEGKLCTDVTSESLNQLLGSIMKIVVNNLGIDEASWMKRLAVFSQPIVSRAKPEMLKSHFIPTMEKLKKRTSKVVAEEEHLR---LEGKSEGDEEEGTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTFR-DPDAEELFRMVGEVFIFWSKSHNFKREEQNFVVMNEINNMSFLTADSKS-KMSKAGDSEAGGSDVERTKK--KRRGDRYSVQTSLIVAALKKMLPIGLNMCSPADQELINLAKTRYSLKDTDEEVREFLQNNLHLQGKVD-NPSMRWQMALYKEM-----------------AGKAEDADAPENVVKRVQEVSAVLYHIEV------------TEHPFKSKKMVWHKLLSKQRRRAVVACFRMTPLYNLPRHRASNMFLDGYKRNWIRNEGYSFEDRMIDDLSKALE---EEEEEEEEKETKPDPLHQLILHFSRTALTEKS-KLDIDHLYMAYADIMAKSCHMDEEDEGGEEENEGGEEEMSFEVR--QTEMEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGCMVSSTLKLGISILNGGNCEVQQKMLDYLKDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMVSEEG--TNMKLERGEKVMADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINVIICTVDYLLRLQESISDFYWYYSGKDIIDEPGKRNFSKAMTVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQ--------------------DSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKSMDSQKQYTPSEIQFLLSCSEADENEMINYEEFASRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLQNFLEQAESVLNYFRPFLGRIEIMGASRKIERIYFEISEVNRKQWEMPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMNIASQISEQDEEEKEEDDIEEAE------GGDAGDEEGGGEEGQPESSSAFADFIQSIMNFLGMFTFRNIRRQYRRLRKMTIKEIVVGLATFMWTILLGILHFIYSVCKGFFLLIWHTLFGGGLVEGAKNMTVTELLASMPDPTQDEVHGDLPGEPRGGEEQETGGIMDSMDAGGGEEEDEDIQEKDGGKIPG-----------IDTPGGLGDMGDTTPVEPPTPEGTPLLKRKAQPDEAGP-----EQPPAIEEPPPEPEKADIENGEKAEKEVEVKPEPIPEEPKPQRATKAKK--EKKSVKG--AGFELWNELDVQRNKFMNCLSRNFYNIRFLALFLAFALNFILLFYKVSDTPPSSDE-------------------FEGSGIFEGSGLFEGSAEDFEGSGGEDGGDDEDEEGPVYYFLEESTGYMQPTLSFLAILHTVIAFISIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQPADDDIKGQWDRLVLNTPSFPTNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLASLDVSKQQTDKKPEEPDNSMLAWFTSIDIKYQIWKFGVVFTDNTFLYLVWYTVMSLLGHYNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T6W5-1", "uniprot_id": "A0AB32T6W5_DANRE", "id": "A0AB32T6W5-1", "name": "", "aln": "MDIG---EAEDEIQFLRTRDELVLRCCSSG-PHQQKLCLAAEGFGERLCFLESTSNSKNVPADLCVCVFVLDQCLSVRALQEMLANREDLCTA------------SHEAAGRRTLLYGQAVLFRHAYSDMYLCCLSTSGLSSDKLAFDVGLQEDTKGEVCWWTVHPASKQRSEGEKVRVGDDLILVSVSSERYLHVSWTNGEGNDSGVGRVDAAFQQTLWSVAPVSS--GTVKTQGHVRGGDTVRLLHGHTDECLTIRAAKHKPDQHRSVHFEGGLVSLQARSLWRLETLHVVWSGSHIHWGQPFRLRHLTTGSFLGLIHDQGLQLVERDRADVKCTAFAFRASK--EEIAESSDYVKRRDGMGAPEIKYGDSLCFIQHVGTGLWLTYQTTDSKRQKESVSQ-RQAVLQAEGHMDDGITLSRSQREESQAACLIRSSVLLFSQFISRLDDVTQKENITNFN----LPIEMIRLTLQDLLGYFHCPEKGQDHKIRQGDIGALKNRQNLFQDEGIILLVLDCIDHLHVYNSAAHFAEAVG-KEAGECWEGVLNAFYELLAALIRGNRNNCAQFSGS--LDWLVSRLERLEAS--SGILEVLHCVLVESPEALNVIKESHIRTIISLLDKHGRNHKILDVLCSLCVCHGMAVRSNQHLICDTLLPERDLLLQTRLINQVSSVRPNIFLCTRDDSAQYKKWYYEVVVEKAEPFVTAEPTHLRVGWASTEGYRPSPTGGHDWGSNGVGDDLCSYGFDGLQLWTGGVGRRVSS--PNQHLLREDDVISCCLDLSATCISFRVNGQPVQGMLENFCVDGLLFPVVSFSAGVQVRMLFGGRQGEFRFLPPAGFSPCAEALLPKTRCKLELCHELTRNHTETQRDLLGPVVPINPVTFTPVPVDSSQVEYPPQLEQIRERLAENLHELWLIDKIEQGWTYGPVKDEGKKVHSCLVEFSKLPDQERIHSLQSSEDILRTLLAFGVHIGLSDEHAEENVKYVRLS-NKYELWNGYKPAPVDQSRVVLTDAQGELVEYLAENEHNIWARERIRQGWSYGPQQDVKFKRSTQLVPFYLLDERYKQAGRDAMRDALGTLLGFGYTVEPLEKEHASSSSVKSVGA--ERFRIFRLEQLFAVHSGKWYFEFEAVTDGEMRVGWARPGCKPDVDLGSDDQAFVFDGSKGQWWHGG-AERLGGCWKRGDVIGCLLDLTTDTMMITLNGELLLNSHGSEFAVKDLIKS-DGFLPVCSIGINQVGRLNLGCQIESLKFFNVCGLQEGYQPFGLNMSKDLPLWMSWRAPLFIPIQDNHPN-IQVLRVDGTVNNTPCLKVTKRVFGHEERGSGSVGFYRLSMPIECAQVFCGPGDASVPTSSAAICH-----------------------------------------LRDPEDGEVDSDFELLMKAHRYAGSRD-----------------------------ELNNHKDHS----------------------------QEKPSRLKQRFMLKKKQELNTSHSSARLLEEVLA-----------------------IEKNEENRLVRCTTYYYSVRIPFSQEPSCVWVGWVTSKFSHHDVSFDLDSICTVTVTLGDEWGKVHESVKRSSCYMVCAAE---GSSLSH--SRSSNGLEIGCLVDTATGLLTFTANGKEITTYYQVEPGTKLFPAVFAKATSSNVFQFELGCIKNVMPLSAGVFRSERRNANPQCPPRLCVQHLTHTRWTRVPDHTQSVEMSRLEERYGWRAQCSHIQQIMTLYIPEESRCVDILELSESHDLLKFHNHTLLLYSALSAHGNTHVSHALCSHVDQSQLLFALQCSRMPGHLRTSYYNLLINIHLDAHASARQTMNHEYIVPMTN-TQSITLYK------SNEKVERFPGSDRSTSLWPKMHFTSPCFIRSNNKIDLVDGDEGRVLWSSLRQDSPEIPLDVLKAVVIAMLKEAVMVVGQGVRDPTGGSVELLLVPLLNLIHTLLLMGVYQGADLEAVFSLILPSEYMR-----------------------------------------------------------ATQRTEETDELGERD--------------------GGAEEKEKGDWKYDVLLQMKLPEAVKLQVCQLLKYLCDCQVRHRVEAVISFSGDFVGHLQEDQRFRYNEVVDALNMSAALTARKTKEFRSPPQEQINMMLSFRED----CLECPCPEDIQDLMWEFHQDLMSHCGIEIESG-----SENENEDDLSIRNHLHGLVDKIMHLKRRMSGLPEEI---ASKPVSLQQLISETMLHWAQEETIEDPDLVRAVFSLLHQQYAGLHGQMSAPLQKAYCISQTSVEDTLHLQWALACIRSLLKARMGKEEEECMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLDAR------------------ESKEIIFPKMVAHCCRFLCYFCRISRQNQKAMFDHLSYLLDNGNVGLASPSMRGSTPLDVAAASVMDNNELALSLTEADLEKVVQYLGGCGLRSCALLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENAYVVVRLLIRRPECFGPALRGEGANGLLATMEEAIRISNQ--------QDGTTAHSSSRTLDTLDE--DDHDVIHMGHAIMTFYSALIDLLGRCAPETHLIEAGKGEAIRIRAILRSLVPREDLEGIINIPFSLPVVNSDGLVVEPDMSRMFCPDHKAAMVLFLDRVYGVQDQQFVLRLLKFGFLTDLKAAVNMDTTGLGGTDMALAINRYLCVAVLPLLSKYSSLLCDSSSSRSGPVDELLQGVYSLSKASGLTKAQREAIQDCLLAVCGKLKPSMVQPLLRNLVFDVPQLPENSKMPLKLLTNHYEQSRKYYCRSYGFGDFGSASEEELCLTRRLFWGIFSALAKKSYDADLFKLALGCLSAVAGAIPPDHLDLSCTGG--RERHSVMDSERGFCPQPLDTLNVTIPESLEFVVNKYAEHTHEKWSMEKFGNGWVHGEQLSESSKVHPLLKPYRALSEKDKECYRGVIKETVKCMLVLGWTIKRTNEGE--SHGIHNPARRISQSGKLS-FEGASTFSPKPVDTSSVTLTWDQYAMAERLAENYHHIWAARKLQELESKGGGSHPLLVPYDALSVKDKSRVRDKAQDVLKFFHVNGYSVKRNREVADAD-----SPAIASRFAYGLIQQALRLTERAQESVIELDVAQARGQINKAERVPHEQQIHFFIKVLLPLLDQYFKNHHLYFMSTTMSSLRDGCQSTSKEKEMVTSLFCKLGSLARRRISIFGNDALALVNCLQILAQSLDGRMLMKTTSESVRGSIGSFFEAAAEDLELMVENVTLDGLN--RAQKRGDPELIAYTTTALIPVLSAIFQHDSQRQSGAGLILDEVQSCCYRILSSLYILGTC---------SGSFIERQRSVLGECLAALSAAFPVCFLELS----DLHSHFDT--------LSNEGIEEKACKLLPNLHEAFLEVEELAGAGSSARHALLLRVTEVTLPLLCSYVSRWGEVDNQA-------SQEGHCSSVTPQHANALLGYILSIIHAHLGTSDSAWMKRLAVFGQPIINKAEPHLLKRHFLPLMEKLRKRAESVLLEEEHLK---MEGRGDVSEQELDIQERFTVLVQDIYAFYPLLIPFIDLHRMSWLREV-NADAEKLFSLVAEVFIFWAKSHNFKWEEQNFVVQNEINNMAFLVNSSKS-RMN-----KGGVFCQERRKV--KRKADRYSTHTSLIVAAPKKLLSVAMNGCCHGDQGLVSHAKSRFAQRDTEDEVRAYIHS------------------ILQQDL-----------------CGNSVDP----LRVERILSIARVLFHLDQ------------VEHPQKMKRPVWYKMLSKQRKRAVVACLRMAPLYNLPRHRAVNLFLQGYERVWLKAENDSPEDRLIEDLAKAAH--VEILKEGAEQRNRIDPLHQLINLFSQCALTQRS-KLEEDGLYMCYAEIMAKSCQSEEEQDEDG--------LKSFE--------EKEMEKQRLLYQQARLHDRGAAEMILQKLSASRGDMGPMVAATLKLGIAILNGGNTSVQQKMLGYLRRKKDVGFFHSLAGLMQSCSVLDLNAFERQIKAESLGVGAEDN--------SGDKVMADEQLTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDERGQHNFSKAISVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSR--------------------DSSQIELLKALMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSSNVEMILKFFDMFLKLKDLTSSEAFHEYDPDSKGLISKKDFQRAMEVFKRYSQSEIEFLLSCAEMSESELLDYPDFVTRFHEPAKEIGFNMAVLLTNLSEHMPNDARLQNFLELADSVLKYFHPHLGRIEILGSGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNKGGEKEKMELFVNFCEDTIFEMQLAAQISGTESGEELKAKKG------------KEEKEVQKTETLPE--------DQRMTRDLNCFSVRNIR---KHIKSISMKSIISVIFSLFYNVLLFITHAFLGLLWFCLYLLYHIFLSGWIIDVAKEMKLTDLFGDLRDPTMVEAIG-VQDAFRENDNQARVFSSRGNLRGMSLDLSAVSRDPQLLTDIFG--------LCLKRQGGKYTLSSGDHSASLDEFLNTSKYQVEIREE-------DFHAVQDEEEDTETKKAFCSDEDK----------HNKEKKTKRRIRKLSS---SNPDETEIQEWAVWKMISSQKTKLLNCFARNFYNMRLLALFLAFAINFILLFYKVSSTT------------------------------DDVEIAFHDEST--------------KSSQEVYFELEENSGYMKMILHCLAVLHTIISLCCIIGYYCLKVPLVIFKREKELARKLEFDGLYITEQPSEDDIKGQWDRMVINTPSYPSNYWDKFVKRKVMAKYGELYGSARVSELLGLDKAALDFSSGAQERK-RPMQKGILVRLNTTDVKYHIWKLGVVFTDNSFLYLAWYMFVSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGEPMDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEFEFYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNEYFDTVPHGFESHTLQEHNLANYLFFLMYLINKDVTEHTGQESYVWKMFQERCWEFFPVGDCFRKQYEDQLS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24498-2", "uniprot_id": "RYR_DROME", "id": "Q24498-2", "name": "Ryanodine receptor", "aln": "MAEAEGGSEQDDVSFLRTEDMVTLSCTATG----ERVCLAAEGFGNRHCFLENIAD-KNVPPDLSQCVFVIEQALSVRALQELVTAAGSETGKG-------------TGSGHRTLLYGNAILLRHHNSDMYLACLSTS-SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKENEQ------SIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGG-DECLTIPSTWGREAGQNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSNELILVKKEEASIATTTFCLRQE---KDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALETLQSNRRHSIFFQ--KVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGRVDGSSMYQKWYFEVTMDHIEQTTHMMP-HLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYSFGFDGAFLWTGGRKTLVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGVKVRGSFRDFNLDGMFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFGN---LAKNVLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHRDDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMD--KPPARIRPVRLPNEIFMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSENHRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFAGFRTYRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVTKMHAGSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMPDCRIDVTRIPGGADTPPHLKISHNTFETMEKAN--WEFLRLSLPVTCMGEFISEQEKARRWDEIKNRQYRLMREAEIAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEADHMMRGPNRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPFKFFSKKSRDQSREKMGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPVPQGPKQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLHSREFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVGCFVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPVSMLALHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYAIRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKELYSDEEMQHSLRSLVTESVRPQLRMTEITPPVIATSSMPSVSSEPIPDID-----------QLYSPKFPLEVVRQFVMEALKDAVEINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWD------------------------------------------------------------------------------------------------QAFEREGKDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRYIEIKQSD-LPSAVAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDSLMQKVSLNALQEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVEEPE--KKTPEEVFRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVG-ELVRALEKTYVINTRARDDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQSDAPTQSEVAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEG-EGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNFYCTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEKPKSDMPSGLLPNNKQSIVLFLERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDMALAMNRYIGNSILPLLIKHSKFYNE-AENYASLLDATLHTVYRLSKNRMLTKGQREAVSDFLVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYGASSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYGRQMGAPDQPQYMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTYGDIRSDNDRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVALNHRGSTRRQSKPQINEFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVIHPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVELRFSYSLLEKLIQYLDRATINMKLLKPSTTFSR--RSSFKTATRDIKFFSKVVLPLMEKYFSTHRNYFIAIATATNNIG-AASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGIDARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVVLPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHRPALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHS---LEAQDIMVKMESCMPNLETILAEVDQFVESD--KTYNDAPHIIDVILPLLCAYLPFWWSQGPDN----VSPTSGNHVTMVTADHMNPLLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMLHKEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDN-IPEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKVKKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEYDVIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNSNEKGKDKTQETVDRIVAMAKVLFGLHM------------IDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARSYYEQWLQEENVG-QEVMVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGAMTERSGALQEDLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTS------IHEQEMEKQKLLFHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGA--------AGEKNMHDAEFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSK--------------------HSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLADLIESPSFHEVDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRAFVEHFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRIERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMATDDGGGNVKRDT--------AYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANIKHQIGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEPVVEEETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSP---------------EDGAAASGELVEGEPHQEPISIVDLLGGEAAKKA---------AQERQEAQKAQEAAMASIEAEAK-----------------------------KSSSAPQETPAVHQIDFSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFTEEADSS---------------AEEELILGSGSGGGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACLHSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSTFAAQESE--------ETGIFKYIMNIDWRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEED-EEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVGDCFRKQYEDELSGGGGGG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::::.**** * :.* * : :.**:.**:*:* *:** :: : :*.**. * *:::*.********::: ..*:******:*:*:** * *** **.** .***:*****: .: **.****:**************:***:*****::***** : . . *:*:* * *.: * : *.: **..:*::** **.*:: :. :*.* :******:* : *:*. :.* :.:*:**::** :* ..: * : . .: ::* :* . :: . : : :* . ****:: : * :.**::* : : * . : ::..: **:*** : .* **::* :* . *:.:*: : . : . : *:**: ** *.. *: :* : :* :**.**::**:: :: ..:*:::: .: . : ::. .*. : . :*:***::*:**: **: *. . *:**.*:* :* **:*:**:*:* :*** **:: . **: **:** ****: *:**:* ***: :*:***:.*. * : *** ::***** ::: . *:*****: :.:. * ***:*: :: . ***:*** :.*: * * .*. **.******* *:**** **:* * . : : **:. .:**... ::* .** *:* :..* **::**.:* *: :. *:*:** :* ::* ** *::. :.::*: :: . * *. * * *:*: : * ::.::::**** **:* : :** ** :* :*: :: *.**..* .** *: :. : : *:*::::* :: . :: :*. : : .****:*:* 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*::.: . :. . :..* : *::* .:****:****:. * :. ::*. .**.*::::. ::. ***:.**: ::***: : : : :. : :* *: :* **: ***.**: :. *::: ::*:*: ***.*..**. * * .:.::*** *::: *** . * ..:* : :** *: ** .:*.:*:: .:: :*: *: *: *:. *:***: :: : : *.*::* * : : *: . :::*: *: *: : .* * .:. : :* ::*:. ::* ::* ** :* :* ::. * :.::. . : : * . * :.*: : *.* :*** *. *. :* **:. ** ** ***** *: *:* : *::: :.:*::: .* : : : : .:: **:: :::: : : : : :. : . . ::*:** *::***:::**..* **:: . . :: *****::.:***:. * *.*: ** * * **::* : :* * : *. : :: .: *:: :::*: *: . . : *.. .::*:*: :*:* : * ::* ::* ..*: : ::* *** *. ..**.**. ..:*:.:** : * * . :* *. : :: : :. : : :: **:** *:. * . : : :..: . :* :: :: ::* .:..**.*:*.: * *: .. .:*: *:* :::*:: : :*: :: .. : .. : : : * :*:*::**:** ::* :* * ..: .*: *.: . *:.* ::* :: . .: *:: . . ::**:** *::*.:.:* :* *: .* *: : .: :* :. * . * *: :: .:: :. : * : .: :: .::* **:***:**:* :.*:.:* **: *:* .* *: * :: :::**::. * : *** *:: *.: *:*:: *: * ** .*:.: *** * . *::****: *::*:** **.***:* :**.:* . ** **:***::*.*** :* **.:*: *::.*** *: .** :* . :*: : * : .* : : ::* ****:** ***** ::**:**** *..**:*::*.***:***:**** ****:**.*:::: *: ** **: *:.*:**:*** ***** ***:********** ***.:*::* **:: .***: *** *::* :**:.*:**:******** *.:**** ****:.***:***:******* *: * *:: . .* :: ::* . *: *.:: * :***:* * ... :: *. :*:**:::****:**********:*::.** :*: * *:*.**.*.******:*..::***:****.: . *** **::**** *::.:*.:**: **:* **.****:**** *: : : : .:: .: : . . : . : :: . . : : : . : * . : . : * . * : : : ::****.:: :**.:**::**:******: . . ::*. ** : : :*::::: :..* **:**.:******:**:***:**:::*** :**.*.:**::*: : *:* ********:** *:.: :. :::***:: :: .: : . * :*::** ** :***:*** ** .*::*::******.****:*:*.*******.*********::** **:::**:***:********* .** : * **.**:**::**:* ************ ** ** :*.**::**********:******************** *.*:::**::*****:*.::** .****::*. :*******:****:**** **:****:***:*:*:*.*:***.**********:*. ", "identical_positions": 1442, "similar_positions": 1443, "identity": "26.59%" }, { "cls_id": "homologset.agr.FB:FBgn0011288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60880-1", "uniprot_id": "SNP25_HUMAN", "id": "P60880-1", "name": "Synaptosomal-associated protein 25", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDAD-----------------------------------MRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCG--LCVCPCNKLK---SSDAYKKAWGNNQDG----------VVASQPARVVDEREQM----AISGGFIRR----------VTNDAREN----EMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60881-1", "uniprot_id": "SNP25_RAT", "id": "P60881-1", "name": "Synaptosomal-associated protein 25", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDAD-----------------------------------MRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCG--LCVCPCNKLK---SSDAYKKAWGNNQDG----------VVASQPARVVDEREQM----AISGGFIRR----------VTNDAREN----EMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60879-1", "uniprot_id": "SNP25_MOUSE", "id": "P60879-1", "name": "Synaptosomal-associated protein 25", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDAD-----------------------------------MRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCG--LCVCPCNKLK---SSDAYKKAWGNNQDG----------VVASQPARVVDEREQM----AISGGFIRR----------VTNDAREN----EMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TZ66-1", "uniprot_id": "SN25A_DANRE", "id": "Q5TZ66-1", "name": "Synaptosomal-associated protein 25-A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEDSD-----------------------------------MRNELADMQQRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKDAEKNLNDLGKFCG--LCSCPCNKMK---SGAS--KAWGNNQDG----------VVASQPARVVDEREQM----AISGGFIRR----------VTDDAREN----EMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PC54-1", "uniprot_id": "SN25B_DANRE", "id": "Q6PC54-1", "name": "Synaptosomal-associated protein 25-B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADESD-----------------------------------MRNELNDMQARADQLGDESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGNLCG--LCPCPCNKLK---GGGQ---SWGNNQDG----------VVSSQPARVVDEREQM----AISGGFIRR----------VTNDAREN----EMDENLEQVGSIIGNLRHMALDMGNEIDTQNRQIDRIMDMADSNKTRIDEANQRATKMLGSG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36975-1", "uniprot_id": "SNP25_DROME", "id": "P36975-1", "name": "Synaptosomal-associated protein 25", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPADPSEEVAP----------------------------QVPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEKNLSGMEKCCG--ICVLPCNKSQ---SFKEDDGTWKGNDDGK---------VVNNQPQRVMDDRNGM----MAQAGYIGR----------ITNDARED----EMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQRAHQLLK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O00161-1", "uniprot_id": "SNP23_HUMAN", "id": "O00161-1", "name": "Synaptosomal-associated protein 23", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNLSS----------------------------------------EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNKCCG--LCVCPCNRTKNFESGKAYKTTWGDGGENSPCN------VVSKQPGPVTNGQLQQPTTGAASGGYIKR----------ITNDARED----EMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70377-1", "uniprot_id": "SNP23_RAT", "id": "O70377-1", "name": "Synaptosomal-associated protein 23", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDLSP----------------------------------------EEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCG--LCVCPCNRTKNFESGKNYKATWGDGGDSSPSN------VVSKQPSRITNGQPQQ-TTGAASGGYIKR----------ITNDARED----EMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40357-1", "uniprot_id": "SEC9_YEAST", "id": "P40357-1", "name": "Protein transport protein SEC9", "aln": "MGLKKFFKIKPPEEATPEQNKDTLMELGISVKNPSKKRKEKFAAYGKFANDKAEDKVYAPPGYEQYARPQDELEDLNASPLDANANEATAGSNRGSSGTQDLGNGAESNSMQDPYAIENDDYRYDDDPYARFQANKSNGRGSVNAAPYGDYGGGYNGTSLNSYNNDGPYSNQNTSNSWVNANGRNSLNHSNSTLNVGPSRQTRQPPVSTSTNSLSLDQRSPLANPMQEKRNPYADMNSYGGAYDSNTNRSSGTRQGSSKNANPYASMANDSYSNGNLNRSANPYSSRSVRQPQSQQAPMTYTPSFIASDEAARNSEVDLNEEPRTGEFDFEEVYADKSAENRAALDEPDLNAVMTNEDSIDLNASEVDHSSRQQQQQQWFMDEQQQQQQHFNATNNQYGDQRGYKTFEEIQKEEEARQQQEEDEAVDEIKQEIKFTKQSSVASTRNTLKMAQDAERAGMNTLGMLGHQSEQLNNVEGNLDLMKVQNKVADEKVAELKKLNRSILAVHVSNPFNSKRRRREREEQLKNRKIEEKLMREQTSQQLSQSTQRIEGAMNANNNISEVRERYQRKNVLEKAKRYQFENDEEDDEMELEIDRNLDQIQQVSNRLKKMALTTGKELDSQQKRLNNIEESTDDLDINLHMNTNRLAGIR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: . . :.*: ***. * : ::: **:.*: *..* ***:.:* .:* :: : : :::.: : : :. .* : . : ... : . : : . :* .:: *::.*: *: : ..*:.*** *.*:: *: ::..* : .: . * : ", "identical_positions": 30, "similar_positions": 75, "identity": "4.59%" }, { "cls_id": "homologset.agr.FB:FBgn0011289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08949-1", "uniprot_id": "TF2AA_RAT", "id": "O08949-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "----------------------------------------------MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQ---------------------------------------------------QQQHHHHHH-HQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASSITSAAATAATLALPAGVT---PVQQILTNSGQLLQVVRAANG--------------------AQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQ---QILFTGNKTQVIPTTVAAPTPAQAQIPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDD---------------------EEEDKEKDGAEDGQ-----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52655-1", "uniprot_id": "TF2AA_HUMAN", "id": "P52655-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "----------------------------------------------MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQ---------------------------------------------------QQQHHHHHH-HQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMS-AAATAATLALPAGVT---PVQQILTNSGQLLQVVRAANG--------------------AQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQ---QILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDD---------------------EEEDKEKDGAEDGQ-----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PM3-1", "uniprot_id": "TF2AA_MOUSE", "id": "Q99PM3-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "----------------------------------------------MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQ---------------------------------------------------QQQHHHHHHQHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLLQHMNASSITSAAATAATLALPAGVT---PVQQLLTNSGQLLQVVRAANG--------------------AQYILQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQ---QILFTGNKTQVIPTTVAAPAPAQAPMPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDD---------------------EEEDKEKDGAEDGQ-----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4I4-1", "uniprot_id": "TF2AY_MOUSE", "id": "Q8R4I4-1", "name": "TFIIA-alpha and beta-like factor", "aln": "-------------------------------------------------MAFINLVPKLYQSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSTQVPLLTLQLPHALPPALQP-EASLLIPAGRTLPSFTPEDLNTANCGANFAFAGYPIHVPAGMAFQTASGHLYKVNVPVMVTQTSGRTEILQHPFQQVLQQLGQPLVIQTTVPTLHPCSLQAATEKSLRMEAVLQPPPILHPPPVDRTHVENAASDRRLLPGNE--------LRPQESSPYLSLPGVGFPPQAALTESSLEPVLGVSASLTQNLHSDPFSQGPPGPLHHHLLESQLQSLKDSIYGCDSTKQLRKAEEPSSLRVSEKNCTSERDLNIRVTDDDINEIIQIDGTGDNSSTEEMGSIRDADENEFPGIIDAGDLNVL-EEVDSVSNEDSTANSSDNEDHQINAPEEDPLNSGDDVSEQDVPDLFDTENVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F7R8-1", "uniprot_id": "F7F7R8_RAT", "id": "F7F7R8-1", "name": "", "aln": "MLAFSFSILGESSAPSGLAVAQQRAPAVQKRAWRLSATQAQTVGRRAASMAFVNLVPKLYRSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWETKVLQSKATEDFFRNSVQAPLFTLQLPHGLPPALQS-TASLLIPAGRTLQSFTPEDLN-ASCAANFAFPGYPIHVPAGMALQTASGHLYKVNVPVVVTQTSGRAEILQHPFQQVLQQLGQPSIIQTTVPTLHPCSLQAETEKSHRMETALQQPTVLHSTPVDRKHTENATSERRVLPGNE--------LRPQESTQYISLPGVGFPPQVALTESSLEPVLGASANLTQNLHGGPFTQGPPGTLRHHVLDTQLHSLRDRIYGCDSVKQLRKIEEPSSLRVSEKSCTSERDLNIQVTDDDINEIIQIDGTGDNSSAEEGGSIRDADENEFPGIIEAGDLKVLEEEVDSVSNEDSTANSSDNEDHQIDALEEDPLNSGDDVSEQDAPDLFDTDNVIVCQYDKIHRSKNRWKFYLKDGVMCFGGRDYVFAKAIGEAEW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNN4-1", "uniprot_id": "TF2AY_HUMAN", "id": "Q9UNN4-1", "name": "TFIIA-alpha and beta-like factor", "aln": "-------------------------------------------------MACLNPVPKLYRSVIEDVIEGVRNLFAEEGIEEQVLKDLKQLWETKVLQSKATEDFFRNSIQSPLFTLQLPHSLHQTLQSSTASLVIPAGRTLPSFTTAELGTSNSSANFTFPGYPIHVPAGVTLQTVSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKSQRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGVVFSPQVSQTNSNVESVLSGSASMAQNLHDESLSTSPHGALHQHVTDIQLHILKNRMYGCDSVKQPRNIEEPSNIPVSEKDSNSQVDLSIRVTDDDIGEIIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNEDPQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGRDYVFAKAIGDAEW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52654-1", "uniprot_id": "TF2AA_DROME", "id": "P52654-1", "name": "Transcription initiation factor IIA subunit 1", "aln": "------------------------------------------------MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSGD----------------------------------------------------------------GSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSGIRNGLVPIKQEVNSQNPPPLHPTSAASMMQKQQQAASSG------------------QGSIPIVATLDPNRIMPVNITLPSPAGSASSESRVLTIQVPASALQENQLTQILT----------AHLISSIMSLPTTLASSVLQQHVNAALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDN---------------------DDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32773-1", "uniprot_id": "TOA1_YEAST", "id": "P32773-1", "name": "Transcription initiation factor IIA large subunit", "aln": "--------------------------------------------------MSNAEASRVYEIIVESVVNEVREDFENAGIDEQTLQDLKNIWQKKLTETKVTTFSWDNQFN--------------------------------------------------------------------EGNINGVQNDLNFNLATPGVNSSEFNIKEENTGNEGLILPNINSNNNIPHSGETNINTNTVEATNNSGAT----LNTNTSGNTNADVTSQ------------------------PKIEVKPEIELTINNANITTVENIDDESEKK-------------------------------------DDEEKEEDVEKTRKEKEQIEQVKLQAKKEKRSALLDTDEVGSELD-----------------------------------------------------------DSDDDYLISEGEEDGPDENLMLCLYDKVTRTKARWKCSLKDGVVTINRNDYTFQKAQVEAEWV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*. ::*.*: **: * : *::**.* ::* :*..*: ::.. . . :: : . : :. . . . . . : . . : * . . :* ** .: : :*:::* ***: *:: :** ****:: : .** * *: :*** ", "identical_positions": 36, "similar_positions": 61, "identity": "6.82%" }, { "cls_id": "homologset.agr.FB:FBgn0011290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ70-1", "uniprot_id": "A0A0G2JZ70_RAT", "id": "A0A0G2JZ70-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAASPYSGLTAVADVIKDLDTQIALIGLGPHSSKKKQDLDKLYELKCKAGQIMNQFGPSALINLSSFSSIKPE-------PASTPPQGSMANSTTVGKMPGTPGTGGRLSPENNQ------------------------------------------------------------------VLTKKKLQDLVREVDPNEQ-----LDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE65-1", "uniprot_id": "TAF12_MOUSE", "id": "Q8VE65-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQFGPSALINLSSFSSVKPE-------PASTPPQGSMANSTTVGKIAGTPGTGGRLSPENNQ------------------------------------------------------------------VLTKKKLQDLVREVDPNEQ-----LDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16514-1", "uniprot_id": "TAF12_HUMAN", "id": "Q16514-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQFGPSALINLSNFSSIKPE-------PASTPPQGSMANSTAVVKIPGTPGAGGRLSPENNQ------------------------------------------------------------------VLTKKKLQDLVREVDPNEQ-----LDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49905-1", "uniprot_id": "TAF12_DROME", "id": "P49905-1", "name": "Transcription initiation factor TFIID subunit 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDLFTTFDSNGVAEHHLHHNHNSTSSASGLLHDPPMASPSQHSPMTNNSNSSSQNGG-------PVSGLGTGTGPISGGSKSSNHTSSAAG---SENTP------------------------------------------------------------------MLTKPRLTELVREVDTTTQ-----LDEDVEELLLQIIDDFVEDTVKSTSAFAKHRKSNKIEVRDVQLHFERKYNMWIPGFGTDELRPYKRAAVTEAHKQRLALIRKTIKKY---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03761-1", "uniprot_id": "TAF12_YEAST", "id": "Q03761-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF12", "aln": "MSSNPENSGVNANNNTGTGNADAITGAQQNMVLQPRQLQEMAAKFRTLLTEARNVGETTPRGKELMFQAAKIKQVYDALTLNRRRQQAAQAYNNTSNSNSSNPASIPTENVPNSSQQQQQQQQQTRNNSNKFSNMIKQVLTPEENQEYEKLWQNFQVRHTSIKEKETYLKQNIDRLEQEINKQTDEGPKQQLQEKKIELLNDWKVLKIEYTKLFNNYQNSKKTFYVECARHNPALHKFLQESTQQQRVQQQRVQQQQQQQQQQQQQQQQQQQQQQQRQGQNQRKISSSNSTEIPSVTGPDALKSQQQQQNTITATNNPRGNVNTSQTEQSKAKVTNVNATASMLNNISSSKSAIFKQTEPAIPISENISTKTPAPVAYRSNRPTITGGSAMNASALNTPATTKLPPYEMDTQRVMSKRKLRELVKTVGIDEGDGETVIDGDVEELLLDLADDFVTNVTAFSCRLAKHRKSDNLEARDIQLHLERNWNIRIPGYSADEIRSTRKWNPSQNYNQKLQSITSDKVAAAKNNGNNVASLNTKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . :. .: : ..: *. * . .... . *. :::* :* :**: *. :* ****:**:: ***: ... :. :*:****..:*.:*:***:**::*: ***:.::*:*. :: :: ::*:: * . ", "identical_positions": 38, "similar_positions": 64, "identity": "7.05%" }, { "cls_id": "homologset.agr.FB:FBgn0011291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U1X0-1", "uniprot_id": "TAF11_RAT", "id": "Q5U1X0-1", "name": "Transcription initiation factor TFIID subunit 11", "aln": "-------------------MDNLGESPTDKAGEPGESEETRATPGAPVSADTEGIPEETDQVGDADSKEAAAEESELKSQDVSDVTAAEREDPSLLTPAAKKLKLDTKDKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGE--------------------------------------------------------------------------------------------------------------MPPLQPKHMREAVRRLKSK-GQIPNSKHKKITFF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JX1-1", "uniprot_id": "TAF11_MOUSE", "id": "Q99JX1-1", "name": "Transcription initiation factor TFIID subunit 11", "aln": "-------------------MDNLGESPTDKGGEPGESEETRATPGALVAADTEGIPEETDRDGDADLKEAAAEESELKSQDVSDVTAAERENSSLLTPAAKKLKLDIKDKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHMREAVRRLKSK-GQIPNSKHKKITFF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFP5-1", "uniprot_id": "A0A8I6AFP5_RAT", "id": "A0A8I6AFP5-1", "name": "Transcription initiation factor TFIID subunit 11", "aln": "-------------------MENLGESPTDKGG---ESEESRATPGNPLAADTEGIPEETDRDGDVDLKEAAAEERETKSQDVSGLTAVERED-SFLTPAAKKLKLETKDKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGE--------------------------------------------------------------------------------------------------------------MPPLQPKHMREAVRRLKSK-GQIPSSKHKKITFF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15544-1", "uniprot_id": "TAF11_HUMAN", "id": "Q15544-1", "name": "Transcription initiation factor TFIID subunit 11", "aln": "-------------------MDDAHESPSDKGGETGESDETAAVPGDPGATDTDGIPEETDGDADVDLKEAAAEEGELESQDVSDLTTVEREDSSLLNPAAKKLKIDTKEKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGE--------------------------------------------------------------------------------------------------------------MPPLQPKHMREAVRRLKSK-GQIPNSKHKKIIFF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PPW3-1", "uniprot_id": "TFKLL_HUMAN", "id": "A0A1W2PPW3-1", "name": "TATA-box-binding protein-associated factor 11-like protein 12", "aln": "---------------------------METGRQRGASAEMFAMPQGLKGSNKDGIPEDLDG----NLEEPRDQESELRSQDVMDLTEGDNEASASAPPAAKRQKTDTKGKKERKPTVDAEEAQ-MTTLLYAMSEEQLSRYEVCRRSAFPKARIAALMQSITGRSVSENTAIAMAGIAKVLVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHLREAVRRLKPK-GLFPNSNYKKIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PQ09-1", "uniprot_id": "TFKLK_HUMAN", "id": "A0A1W2PQ09-1", "name": "TATA-box-binding protein-associated factor 11-like protein 11", "aln": "---------------------------METGRQRDASAEMFPMPRGLKYSNKDGIPEDLDG----NLEEPRDQESELRSQDVMDLTEGDNEASASTPPSAKRQKTDTKGKKERKPTMDAEEAQRMTTLFSAMSEEQLSRYEVCRRSAFPKARIAALMQSITGRSVSENTAIAMAGIAKVFVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHLREAVRRLKPK-GILPNSNYKKIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PRN6-1", "uniprot_id": "A0A1W2PRN6_HUMAN", "id": "A0A1W2PRN6-1", "name": "", "aln": "---------------------------METGRQAGVSAEMFAMPRGLKGSNKDGIPEDLDG----NLEEPRDQEGELRSQDVMDLTEGDKETSASAPPAAKRLKTDTKGKKERKPTVDAEEAQRMTTLLSAMSEEQLARYEVCRQSAFPKARIAALMQSITGSSVSENVAIAMAGIAKVLVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------MPPLQPKHLREAVRRLKPK-GLFPNSNYKKFMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PR64-1", "uniprot_id": "TFKL9_HUMAN", "id": "A0A1W2PR64-1", "name": "TATA-box-binding protein-associated factor 11-like protein 9", "aln": "---------------------------METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDG----NLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHLREAVRRLKPK-GLFPNSNCRRIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PP81-1", "uniprot_id": "TFKL5_HUMAN", "id": "A0A1W2PP81-1", "name": "TATA-box-binding protein-associated factor 11-like protein 5", "aln": "---------------------------METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDG----NLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHLREAVRRLKPK-GLFPNSNCKRIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PRV1-1", "uniprot_id": "TFKL3_HUMAN", "id": "A0A1W2PRV1-1", "name": "TATA-box-binding protein-associated factor 11-like protein 3", "aln": "---------------------------METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDG----NLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------TLPLQPKHLREAVRRLKPK-GLFPNSNCKRIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PPE2-1", "uniprot_id": "TFKL4_HUMAN", "id": "A0A1W2PPE2-1", "name": "TATA-box-binding protein-associated factor 11-like protein 4", "aln": "---------------------------METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDG----NLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSSMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHLREAVRRLKPK-GLFPNSNCKRIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PPH5-1", "uniprot_id": "TFLM_HUMAN", "id": "A0A1W2PPH5-1", "name": "TATA-box-binding protein-associated factor 11-like protein 13", "aln": "---------------------------METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDG----NLEEPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKRKKERKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARIAGLMRSITGSSVSENAAIAMAGIAKVFVGEVVEEALDMCEMWGE--------------------------------------------------------------------------------------------------------------TPPLQPKHLREAVHRLKPK-GLFPNSNYKRVMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NLC8-1", "uniprot_id": "TFKL2_HUMAN", "id": "A6NLC8-1", "name": "TATA-box binding protein associated factor 11 like protein 2", "aln": "---------------------------METGRQTGVSAEMFAMPRDLKGSKKDGIPEDLDG----NLEEPRDQEGELRSEDVMDLTEGDNEASASAPPAAKRRKTDTKGKKERKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPKACIAGLMRSITGRSVSENVAIAMAGIAKVFVGEVVEEALDVCEMWGE--------------------------------------------------------------------------------------------------------------MPPLQPKHLREAVRRLKPK-GLFPNSNYKKIMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1W2PPL8-1", "uniprot_id": "TFKLN_HUMAN", "id": "A0A1W2PPL8-1", "name": "TATA-box-binding protein-associated factor 11-like protein 14", "aln": "---------------------------METGRQTGVSAEMFAIPRGLKGCNEDGIPEALDG----NLEEPRAQECELRSEDVMDLTVVDNEASASAPPAAKRQKTDTKGQKERKPSVDAEEAQRMTTLLSAMSEEQLSRYEVCRQLAFPKALVARLMWSITGRSVPENMAIAMAGIAKVFVGEVVEEALDMCEMWGE--------------------------------------------------------------------------------------------------------------MPPLQPMDLREAVCRLKPK-GLFPN-NYKKVMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49906-1", "uniprot_id": "TAF11_DROME", "id": "P49906-1", "name": "Transcription initiation factor TFIID subunit 11", "aln": "------------------------------------MDEILFPTQQKSNSLSDGDDVDLKFFQSASGERKDSDTSDPGNDADRDGKDADGDNDNKNTDGDGDSGEPAHKKLKTKKELEEEERERMQVLVSNFTEEQLDRYEMYRRSAFPKAAVKRLMQTITGCSVSQNVVIAMSGIAKVFVGEVVEEALDVMEAQGE--------------------------------------------------------------------------------------------------------------SGALQPKFIREAVRRLRTK-DRMPIGRYQQPYFRLN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04226-1", "uniprot_id": "TAF11_YEAST", "id": "Q04226-1", "name": "Transcription initiation factor TFIID subunit 11", "aln": "MTEPQGPLDTIPKVNYPPILTIANYFSTKQMIDQVISEDQDYVTWKLQNLRTGGTSINNQLNKYPKYKYQKTRINQQDPDSINKVPENLIFPQDILQQQTQNSNYEDTNTNEDENEK-LAQDEQFKLLVTNLDKDQTNRFEVFHRTSLNKTQVKKLASTVANQTISENIRVFLQAVGKIYAGEIIELAMIVKNKWLTSQMCIEFDKRTKIGYKLKKYLKKLTFSIIENQQYKQDYQSDSVPEDEPDFYFDDEEVDKRETTLGNSLLQSKSLQQSDHNSQDLKLQLIEQYNKLVLQFNKLDVSIEKYNNSPLLPEHIREAWRLYRLQSDTLPNAYWRTQGEGQGSMFR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . . : : : : : : : : *. : ::* *:*: :: :: :: : * :::. ::.:* : : .:.*: .**::* *: : : .* * :*** : : . :* : ", "identical_positions": 18, "similar_positions": 52, "identity": "5.19%" }, { "cls_id": "homologset.agr.FB:FBgn0011294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06678-1", "uniprot_id": "RM35_YEAST", "id": "Q06678-1", "name": "Large ribosomal subunit protein mL38", "aln": "MLRRSIHTTKILQKPNATSHIWSDFTTRPSSLSIQSSKVKNYLFQKKASLDPPSISRRSNRIKYSPPEHIDEIFRMSYDFLEQRSSKFYELANKTKNPLKKDALLIKAEINNPEVQYNFQFNNKLNNVKDIIDYDVPVYRHLGKQHWESYGQMLLMQRLETLAAIPDTLPTLVPRAEVNIKFPFSTGVNKWIEPGEFLSSNVTSMRPIFKIQEYELVNVEKQLYTVLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNIIADYLPPVPEKNAGKQRFVVWVFRQPLIEDKQGPNMLEIDRKELSRDDFDIRQFTKKYNL-TAIGAHIWRSEWDAKVAAVR-EKYGLPPGRVFSRVRR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54185-1", "uniprot_id": "OBA5_DROME", "id": "P54185-1", "name": "Putative odorant-binding protein A5", "aln": "-------------------------------------------------------------------------------------------------------------MKLPALHLLFLG-----------------FICLARSQDNDENVRRIMKEMEVIPEILDEP----PRELLRIKYDNTIDI----EEGKTYTPTELKFQPRLDWNADPES-----FYTVLMICPDAPNRENPMYRSWLHWLVVNVPG---------LDIMKGQPISEYFGPLPPKDSGIQRYLILVYQQSDKLDFDEKKMELSNADGHS--NFDVMKFTQKYEMGSPVAGNIFQSRWDEYVPELMKTLYGVSE---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :: * : *.:.: :. . :*:.:*.:. * * ** :.**: : .: * *: :.. .::* :. : :****:: **.*: .* ::: * : :**: .: ..: *::*: *:* *::* **::: *::*. * : :* : . * :**: :**:**:: :.:..:*::*.** *. : **:. ", "identical_positions": 51, "similar_positions": 87, "identity": "13.82%" }, { "cls_id": "homologset.agr.FB:FBgn0011296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35878-1", "uniprot_id": "HSPB2_RAT", "id": "O35878-1", "name": "Heat shock protein beta-2", "aln": "---MSGRTVPHAHPATAEYEFAN---PSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAARAGEGGRA----GASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEVARVEP------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PR8-1", "uniprot_id": "HSPB2_MOUSE", "id": "Q99PR8-1", "name": "Heat shock protein beta-2", "aln": "---MSGRTVPHAHPATAEYEFAN---PSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAARAGEGARA----GASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEIARVEP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16082-1", "uniprot_id": "HSPB2_HUMAN", "id": "Q16082-1", "name": "Heat shock protein beta-2", "aln": "---MSGRSVPHAHPATAEYEFAN---PSRLGEQRFGEGLLPEEILTP--TLYHGYYVRPRAAPAGEGSRA----GASE-----------------------LRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97541-1", "uniprot_id": "HSPB6_RAT", "id": "P97541-1", "name": "Heat shock protein beta-6", "aln": "--MEIRVPVQPSWLRRASAPLPGFSTPGRLFDQRFGEGLLEAELASLCPAAIAPYYLR------APSVAL----PTAQ-----------------------VPTDPGYFSVLLDVKHFSPEEISVKVVGDHVEVHARHEERPDEHGFIAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQ-----------------ATPASAQASLPSPPAAK---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5EBG6-1", "uniprot_id": "HSPB6_MOUSE", "id": "Q5EBG6-1", "name": "Heat shock protein beta-6", "aln": "--MEIPVPVQPSWLRRASAPLPGFSAPGRLFDQRFGEGLLEAELASLCPAAIAPYYLR------APSVAL----PTAQ-----------------------VSTDSGYFSVLLDVKHFLPEEISVKVVDDHVEVHARHEERPDEHGFIAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQ-----------------ATPASAQAQLPSPPAAK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14558-1", "uniprot_id": "HSPB6_HUMAN", "id": "O14558-1", "name": "Heat shock protein beta-6", "aln": "--MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLR------APSVAL----PVAQ-----------------------VPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQ-----------------AAPASAQA--PPPAAAK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24623-1", "uniprot_id": "CRYAA_RAT", "id": "P24623-1", "name": "Alpha-crystallin A chain", "aln": "----MDVTIQHPWFKRALGPFY----PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR---TVLDS----GISELMTHMWFVMHQPHAGNPKNNPGKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSER--AIPVSREEKPSSAPSS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24622-1", "uniprot_id": "CRYAA_MOUSE", "id": "P24622-1", "name": "Alpha-crystallin A chain", "aln": "----MDVTIQHPWFKRALGPFY----PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR---TVLDS----GISELMTHMWFVMHQPHAGNPKNNPVKVRSDRDKFVIFLDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSER--AIPVSREEKPSSAPSS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02489-1", "uniprot_id": "CRYAA_HUMAN", "id": "P02489-1", "name": "Alpha-crystallin A chain", "aln": "----MDVTIQHPWFKRTLGPFY----PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR---TVLDS----GISE-----------------------VRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAER--AIPVSREEKPTSAPSS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23928-1", "uniprot_id": "CRYAB_RAT", "id": "P23928-1", "name": "Alpha-crystallin B chain", "aln": "----MDIAIHHPWIRRPFFPFHS---PSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDT----GLSE-----------------------MRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQA----SGPER--TIPITREEKPAVTAAPKK--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23927-1", "uniprot_id": "CRYAB_MOUSE", "id": "P23927-1", "name": "Alpha-crystallin B chain", "aln": "----MDIAIHHPWIRRPFFPFHS---PSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDT----GLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPER--TIPITREEKPAVAAAPKK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02511-1", "uniprot_id": "CRYAB_HUMAN", "id": "P02511-1", "name": "Alpha-crystallin B chain", "aln": "----MDIAIHHPWIRRPFFPFHS---PSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDT----GLSE-----------------------MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPER--TIPITREEKPAVTAAPKK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8E3-1", "uniprot_id": "A0A8M9Q8E3_DANRE", "id": "A0A8M9Q8E3-1", "name": "Alpha-crystallin B chain", "aln": "----MDIAINPP-FRRILFPIFF---PRRQ----FGEHITEADVISS------LYSQRSSFLRSPSWMES----GVSE-----------------------VKMEKDQFSLSLDVKHFAPEELSVKIIGDFIEIHAKHEDRQDGHGFVSREFLRKYRVPVGVDPASITSSLSSDGVLTVTGPLKLS----DGPERTIAIPVTRDDKTTVAGPQKRKKLKQVWNKWRGAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P82147-1", "uniprot_id": "L2EFL_DROME", "id": "P82147-1", "name": "Protein lethal(2)essential for life", "aln": "------MSVVPLMFRDWWDELDFPMRTSRLLDQHFGQGLKRDDLMSSVWNSRPTVLRSGYLRPWHTNSLQKQES------------------------GSTLNIDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTVTSSLSSDGLLTIKAPMKALP----PPQTERLVQITQTGPSSKEDNAKKVETSTA--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04792-1", "uniprot_id": "HSPB1_HUMAN", "id": "P04792-1", "name": "Heat shock protein beta-1", "aln": "--MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSG------------VSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQ--SNEITIPVTFESRAQLGGPEAAKSDETAAK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UJY1-1", "uniprot_id": "HSPB8_HUMAN", "id": "Q9UJY1-1", "name": "Heat shock protein beta-8", "aln": "MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEG-------------RTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPP------YSTFGESSFNNELPQDSQEVTCT--------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ** : : ::* * *.:: *: : : .:* :: : * ::: * : :* *: : .:** :* * . ", "identical_positions": 16, "similar_positions": 27, "identity": "6.99%" }, { "cls_id": "homologset.agr.FB:FBgn0011297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92685-1", "uniprot_id": "ALG3_HUMAN", "id": "Q92685-1", "name": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "aln": "MAAGLRKRGRSGSAAQAEGLCKQWLQRAWQER---RLLLREPRYTLLVAACLCLAEVGITFWVIHRVAYTEIDWKAYMAEVEG-VINGTYDYTQLQGDTGPLVYPAGFVYIFMGLYYATSRGTDIRMAQNIFAVLYLATLLLVFLIYHQTCKVPPFVFFFMCCASYRVHSIFVLRLFNDPVAMVLLFLSIN-LLLAQRWGWG-----------CCFFSLAVSVKMNVLLFAPGLLF--LLLTQFGFRGALPKLGICAGLQVVLGLPFLLENPSGYLSRSFDLGRQFLFHWTVNWRFLPEALFLHRAFHLALLTAHLTLLLLFALCRWH---------RTGESILSLLRDP-------------------------------------SKRKVPPQPLTPNQIVS--------------TLFTSNFIG----ICFSRSLHYQFYVWYFHTLPYLLWAMPAR-------WLTHLLRLLVLGLIELSWNTYPSTSCSSAALHICHAVILLQLWLGPQPFPKSTQHSKKAH---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2A8-1", "uniprot_id": "ALG3_MOUSE", "id": "Q8K2A8-1", "name": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "aln": "MAAGLRKRGQPASVGQPAGIWKQWLQRAWQER---YLLLREPRYTLLVASCLCIAEVGITFWVIHRVAYTEIDWKAYMAQVEG-FINGTYDYTQLQGDTGPLVYPAGFLYIFTGLFYATDRGTDIPMAQNIFAVLYLVTLVLVFLIYHQTSKVPPFVFFFMCCASYRVHSIFVLRLFNDPVAMALLFLSIN-LFLAQCWSWG-----------CCCFSLAVSVKMNVLLFAPGLLF--LLLTQFGFRGALPKLAICAALQVVLGLPFLLENPIGYLSRSFDLGRQFLFQWTVNWRFLPETIFLHRAFHLALLAAHLSLLLLFALCRWH---------RTGESILALLKDP-------------------------------------SKRKVPPQALTPNQIVS--------------ILFTSNFIG----ICFSRSLHYQFYVWYFHTLPYLLWAMPAR-------WLTHLLRLLVLGLIELSWNTYPSTSFSSAALHLCHAVVLLQLWLSPESFPKSIQPSRKTH---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8K7-1", "uniprot_id": "F1M8K7_RAT", "id": "F1M8K7-1", "name": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "aln": "MAAGLRKRGLPGSVVQPAGIWKQWLQRAWQER---YLLLREPRYTLMVASCLCLAEVGITFWVIHRVAYTEIDWKAYMAQVEG-FINGTYDYTQLQGDTGPLVYPAGFLYIFTGLYYATDRGTDIPTAQNIFAVLYLVTLVLVFLIYHQTSKVPPFVFFFMCCASYRVHSIFVLRLFNDPVAMALLFLSVN-LFLAQRWSWG-----------CCCFSLAVSVKMNVLLFAPGLLF--LLLTQFGFRGALPKLALCAALQVVLGLPFLLENPVGYLSRSFDLGRQFLYQWTVNWRLLPEAIFLHRAFHLALLAAHLSFLLLFALCRWH---------RTGESILSLLKDP-------------------------------------SKRKVPPQPLTPNHRLSPSSSPPTSLASASAAPSTPSFMSGTS-TRCPTSCGPRPHAGSHTCSGCWCWDSSSSPGIHTHPHPSALLPYTCATLSPCCSSGCPLSSFLGASSQAGKPTEIHPFLLGLAQHRGWNGLCS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TWS8-1", "uniprot_id": "A0AB32TWS8_DANRE", "id": "A0AB32TWS8-1", "name": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "aln": "MAGGKKKSSTAPSRFQKT------LSSIWQDK---HMVLFKTEYTLLVTAVLWFLEIAINIWVIQKVSYTEIDWKAYMDEVEG-VINGTYDYTQLKGDTGPLVYPAGFVYIFTGLYYLTDHGHNIRLGQYVFAVFYLINLLLVMRIYHRTKKVPPYVFFFICCASYRIHSIFILRLFNDPVAMMLCFGAIN-LFLDGRWTLG-----------CALYSLAVSVKMNVLLFAPGLLF--LLLCEFGLWKTLPRLALCAVIQLVLGLPFLLVNPVGYVSRAFDLGRQFLFKWTVNWRFLPEDVFLNRYFHLALLLAHITTLLLFALKRWK---------RSGSSIWTILKDP-------------------------------------SERKETAHKVNADQMVL--------------ILFTSNFIG----MCFSRSLHYQFYVWYFHTLPYLLWSGGVK-------KLAHLLRVLILGLIELSWNTYPSTNYSSLSLHVCHLIILLCLWLNPNPASPSHRSENKAKSH-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27333-1", "uniprot_id": "ALG3_DROME", "id": "Q27333-1", "name": "Dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase Alg3", "aln": "MAPPKAASHRPAVRRKKSGTLVDSILDKYLNVRFFKYLLLEPAALPIVGLFVLLAELVINVVVIQRVPYTEIDWVAYMQECEG-FLNGTTNYSLLRGDTGPLVYPAAFVYIYSALYYVTSHGTNVRLAQYIFAGIYLLQLALVLRLYSKSRKVPPYVLVLSAFTSYRIHSIYVLRLFNDPVAVLLLYAALN-LFLDRRWTLG-----------STFFSLAVGVKMNILLFAPALLL--FYLANLGLLRTILQLAVCGVIQLLLGAPFLLTHPVEYLRGSFDLGRIFEHKWTVNYRFLSRDLFENRTFHVSLLGLHLLLLLAFAKPTWTFFQSYVRLRRIEDQLQPQIAQQNLELNAQKRPKKVEKDKDKDQKKFTTEQQSFLKAFEKSLQKASGGKATPAPAQAEPERYGIHFDRCTQLALLPFFLCNLVGVACSRSLHYQFYVWYFHSLPYLAWSTPYS----------LGVRCLILGLIEYCWNTYPSTNFSSAALHFTHIILLAGVAKQLVQTMRINNAAKREQQEQQKKLQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38179-1", "uniprot_id": "ALG3_YEAST", "id": "P38179-1", "name": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "aln": "MEGEQSPQGEKSLQRKQFVRPPLDLWQDLKDG--VRYVIFDCRANLIVMPLLILFESMLCKIIIKKVAYTEIDYKAYMEQIEMIQLDGMLDYSQVSGGTGPLVYPAGHVLIYKMMYWLTEGMDHVERGQVFFRYLYLLTLALQMACYYLLHLPP--WCVVLACLSKRLHSIYVLRLFNDCFTTLFMVVTVLGAIVASRCHQRPKLKKSLALVISATYSMAVSIKMNALLYFPAMMISLFILNDANVILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAFNFGRKFMYQWSINWQMMDEEAFNDKRFHLALLISHLIALTTLFVTRYP---------RILPDLWSSLCHP--------------------------------------LRKNAVLNANPAKTIP-------------FVLIASNFIG----VLFSRSLHYQFLSWYHWTLPILIFWSGMP----------FFVGPIWYVLHEWCWNSYPPNSQASTLLLALNTVLLLLLALTQLSGSVALAKSHLRTTSSMEKKLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : : :: . :* : : * : :*::*.*****: *** : * ::* :*: : *.********..: *: ::: *. .: .* .* :** * * : * * .. . * *:***::****** .: : :: :: . :*:**.:*** **: *.::: : * : .. :: * *: :. *** * *: :*::** * .:*::*:::: . * .: **::** *: * : : * .: . : . :* . .. . *: . * : . : : * . . * .. . : : . ", "identical_positions": 82, "similar_positions": 112, "identity": "15.3%" }, { "cls_id": "homologset.agr.FB:FBgn0011300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P80204-1", "uniprot_id": "TGFR1_RAT", "id": "P80204-1", "name": "TGF-beta receptor type-1", "aln": "-----------------------------------------------------------------MEAASAALRRC-----------LLLIVLVAAAT----LLPG-----------------AKALQCFCHLCTKDNFTCETDGLCFVSVTETTD-KVIHNSMCIAEIDLIPRDRPFVCAPSSKT--------GAVT--YCCNQDHCNKIELPTTGPFSEKQSA----------------GLGPVELAAVIAGPVCFVCIALMLMVYICHNRTVIHHRVP--NEEDPSLDRPFISEGTTLKDLIYDMTTSGSG-SGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64729-1", "uniprot_id": "TGFR1_MOUSE", "id": "Q64729-1", "name": "TGF-beta receptor type-1", "aln": "-----------------------------------------------------------------MEAAAAAPRRP-----------QLLIVLVAAAT----LLPG-----------------AKALQCFCHLCTKDNFTCETDGLCFVSVTETTD-KVIHNSMCIAEIDLIPRDRPFVCAPSSKT--------GAVTTTYCCNQDHCNKIELPTTGPFSEKQSA----------------GLGPVELAAVIAGPVCFVCIALMLMVYICHNRTVIHHRVP--NEEDPSLDRPFISEGTTLKDLIYDMTTSGSG-SGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36897-1", "uniprot_id": "TGFR1_HUMAN", "id": "P36897-1", "name": "TGF-beta receptor type-1", "aln": "-----------------------------------------------------------------MEAAVAAPRPR-----------LLLLVLAAAAAAAAALLPG-----------------ATALQCFCHLCTKDNFTCVTDGLCFVSVTETTD-KVIHNSMCIAEIDLIPRDRPFVCAPSSKT--------GSVTTTYCCNQDHCNKIELPTT----VKSSP----------------GLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVP--NEEDPSLDRPFISEGTTLKDLIYDMTTSGSG-SGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70539-1", "uniprot_id": "ACV1C_RAT", "id": "P70539-1", "name": "Activin receptor type-1C", "aln": "-----------------------------------------------------------------MTPARRSALSL------------ALLLVALASD----LAAG--------------------LKCVCLLCDSSNFTCQTEGACWASVMLTNG-KEQVSKSCVSLPELN---AQVFCHSSN-----------NVTKTECCFTDFCNNITQHLPT--ASPD-APR---------------LGPTELTVVITVPVCLLSIAAMLTIWACQDRQCTYRKTKRHNVEEPLAEYSLVNAGKTLKDLIYDATASGSG-SGPPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGLVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQSCEALRVMGRIMRECWYANGAARLTALRVKKTISQLCVKEDCKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K348-1", "uniprot_id": "ACV1C_MOUSE", "id": "Q8K348-1", "name": "Activin receptor type-1C", "aln": "-----------------------------------------------------------------MTPARGSALSL------------ALLLVALAAD----LAAG--------------------LKCVCLLCDSSNFTCQTEGACWASVMLTNG-KEQVIKSCVSLPELN---AQVFCHSSN-----------NVTKTECCFTDFCNNITLHLPT--ASPN-APR---------------LGPTELTVVITVPVCLLSIAAMLTIWACQDRQCTYRKTKRHNVEEALAEYSLVNAGKTLKDLIYDATASGSG-SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNLSIFESFKRADIYSVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQSCEALRVMGRIMRECWYANGAARLTALRVKKTISQLCVKEDCKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NER5-1", "uniprot_id": "ACV1C_HUMAN", "id": "Q8NER5-1", "name": "Activin receptor type-1C", "aln": "-----------------------------------------------------------------MTRALCSALRQ------------ALLLLAAAAE----LSPG--------------------LKCVCLLCDSSNFTCQTEGACWASVMLTNG-KEQVIKSCVSLPELN---AQVFCHSSN-----------NVTKTECCFTDFCNNITLHLPT--ASPN-APK---------------LGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSG-SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80202-1", "uniprot_id": "ACV1B_RAT", "id": "P80202-1", "name": "Activin receptor type-1B", "aln": "----------------------------------------------------------------MAESAGASSFFP-----------LVVLLLAGSGG----SGPRG----------------IQALLCACTSCLQTNYTCETDGACMVSIFNLDG-MEHHVRTCIPKVELVPAGKPFYCLSSE-----------DLRNTHCCYIDFCNKIDLRVPS--GHLK-EPEHPS-----------MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCE-MCLSKDKTLQDLVYDLSTSGSG-SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61271-1", "uniprot_id": "ACV1B_MOUSE", "id": "Q61271-1", "name": "Activin receptor type-1B", "aln": "----------------------------------------------------------------MAESAGASSFFP-----------LVVLLLAGSGG----SGPRG----------------IQALLCACTSCLQTNYTCETDGACMVSIFNLDG-VEHHVRTCIPKVELVPAGKPFYCLSSE-----------DLRNTHCCYIDFCNKIDLRVPS--GHLK-EPAHPS-----------MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCE-MCLSKDKTLQDLVYDLSTSGSG-SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEDYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36896-1", "uniprot_id": "ACV1B_HUMAN", "id": "P36896-1", "name": "Activin receptor type-1B", "aln": "----------------------------------------------------------------MAESAGASSFFP-----------LVVLLLAGSGG----SGPRG----------------VQALLCACTSCLQANYTCETDGACMVSIFNLDG-MEHHVRTCIPKVELVPAGKPFYCLSSE-----------DLRNTHCCYTDYCNRIDLRVPS--GHLK-EPEHPS-----------MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCE-MCLSKDKTLQDLVYDLSTSGSG-SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B949-1", "uniprot_id": "A0A8M2B949_DANRE", "id": "A0A8M2B949-1", "name": "Activin receptor type-1C", "aln": "----------------------------------------------------------------MLRDGNVAVMPPRR---------TAVALLALCGL----LAVG------------------DALKCNCTACESTGYVCETDGACMASTSYINGQEEQQVRICIPRVSLVPPGQPIYCLSAK-----------GLLNTHCCYTDFCNSINLQIPN--GSSTGQTQYLSNVWGIADGKGGSWGPVELVAVIAGPVFLFCLLLIVGVLLFQHHQRNYNHRQRLDVEDPSCDHLYLAKDKTLQDLIFDLSTSGSG-SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNHYSVTIEGMIKLSLSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNGTCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNAGGIHEDYQLPYYDLVPSDPSIEEMRKVVCDQRLRPNVPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQLSVQEDIKI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7L8-1", "uniprot_id": "TGFR1_DROME", "id": "A1Z7L8-1", "name": "Receptor protein serine/threonine kinase babo", "aln": "MLSALRLIFLGALLGASVCASPIEFVMDTSLNGSRSDPATATHPGKWPPTTKAPALRAPAGTAGHAYQSPSSSLAADNRSHDNNNASAVSMLLPQDGDASGAVAPAVTPQLPIYIAQPSAKKPENKIKCHCDTCKESNNICETDGFCFTSVEKNSDGSIIFSYRCLHKSQIFPPGRSIWCNDGLHGGPTARPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVP---HRLTSWEFVAIILGATLFICFTGTSTWYYCQRRKRMASGRT--FAKEDSAYDPILNGNTTIHDII-EMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLASISVEDKVKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: . : * * * . . * *:* * .* . *: .: . * . * *.** : . . *:. :* .. :. : : : :: : ..*::*:: : ::**** :* **:***::** : * . :*********:*:* * :*********:* ***********:***************************::***:***:***. * *::::** *:*******:*:**:***.*****:********. *.*.******:* :::**. . :**********:**:::* . *:*:* **:*:.**: *******. * : ::*******:* .***:***:**** :: **.:** *:: :.*: *.::*:****.* .*******:***::.:. :: * ", "identical_positions": 213, "similar_positions": 121, "identity": "33.92%" }, { "cls_id": "homologset.agr.FB:FBgn0011327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5K5-1", "uniprot_id": "UCHL5_HUMAN", "id": "Q9Y5K5-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "aln": "MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQD-DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAK----EKQNAKKAQETK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUP7-1", "uniprot_id": "UCHL5_MOUSE", "id": "Q9WUP7-1", "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "aln": "MSSNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTPAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQD-DWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAK----EKQNAKKAQETK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9XZ61-1", "uniprot_id": "Q9XZ61_DROME", "id": "Q9XZ61-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "MGDGAGNWCLIESDPGVFTELIREFGCDGAQVEEIWSLDSESFKNLEPIHGLIFLFKWVQEDEPAGKVVLDR--ENIFFAKQVINNACATQAILSLLMNLDHEDIKLGETLTNFKEFCQCFDPYNKGLTLSNASQIRTVHNSFARPTLFELDTKNQKKDDDVYHFVGYMPIGGRLYELDGLREGPIDLGEIKSEQNWIDVVRPIIEKRMQRYSDGEIHFNLMALISDRQRIYEQQIEKLLNPAPN--AMDTEEDR------QAEISSLRTYIEYEIQKKKRYKVENVRRKHNYLPFIVELLKILGENGQLMPIYEKAKQRALEREQAQRKKDTD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..**:***:***********: *** **********:.*.*::*:*:********* :****.** * :.*****************:*:*:* *:*::*****::****.*.**. ***:***:. ** ******* :**:***. *::*.:***.*:*:.***************** :.: :** .***:****:*:**:***:*****::***: ****:* :* . .: .***::. *:*:: : ** *:** ****:**:**********:**** *.*: **:*: **** *:::*:: ::*.", "identical_positions": 199, "similar_positions": 83, "identity": "59.58%" }, { "cls_id": "homologset.agr.FB:FBgn0011336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TDQ1-1", "uniprot_id": "STT3B_MOUSE", "id": "Q3TDQ1-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "aln": "MAEPSAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGTQSAS-SAAAPKPG--PPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILN-TLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLG-DDMKRENPPVEDSSDEDDKRN---PGNLYDKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYN-HDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIREGDYFTQQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIK-FKHLEEAFTSEHWLVRIYKVKAPDNRETLGHKPRVTNIVPKQKYLSKKTTKRKRGYVKNKLVFKKGKKTSKKTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYD7-1", "uniprot_id": "B2RYD7_RAT", "id": "B2RYD7-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "aln": "MAEPSAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGAQSASRAAAAPKPG--PPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILN-TLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSSVFEHYLG-DDMKRENPPVEDSSDEDDRRS---PGNLYDKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYN-HDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIREGDYFTQQGEFRVDRAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIK-FKHLEEAFTSEHWLVRIYKVKAPDNRETLGHKPRVTNIFPKQKYLSKKTTKRKRGYVKNKLVFKKGKKMSKKTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TCJ2-1", "uniprot_id": "STT3B_HUMAN", "id": "Q8TCJ2-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "aln": "MAEPSAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGAQCAHKAAGGAAPPKPAPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILN-TLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLG-DDMKRENPPVEDSSDEDDKRN---QGNLYDKAGKVRKHATEQEKTEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYN-HDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRTLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIRESDYFTPQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIK-FKHLEEAFTSEHWLVRIYKVKAPDNRETLDHKPRVTNIFPKQKYLSKKTTKRKRGYIKNKLVFKKGKKISKKTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ53-1", "uniprot_id": "Q9XZ53_DROME", "id": "Q9XZ53-1", "name": "dolichyl-diphosphooligosaccharide--protein glycotransferase", "aln": "-------MNRTPKMLN----------------------------------------------SKVAGYSSLITFAILLIAWLAGFSSRLFAVIRFESIIHEFDPWFNYRATAYMVQNGWYNFLNWFDERAWYPLGRIVGGTVYPGLMITSGGIHWLLH-VLNIPVHIRDICVFLAPIFSGLTSISTYLLTKELWSAGAGLFAASFIAIVPGYISRSVAGSYDNEGIAIFALQFTYFLWVRSVKTGSVFWSAAAALSYFYMVSAWGGYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIPFVGFQPIRTSEHMAALGVFVLLMAVATLRHLQSVLSRNEFRKLFIVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCAFPVGVWYCIKQINDERVFVVLYAISAVYFAGVMVRLMLTLTPVVCMLAGVAFSGLLDVFLQEDSSKRMGTAISAATEVDEAEDSIEKKTLYDKAGKLKHRTKHDAQQDTGVSSNLKSIVILAVLMLLMMFAVHCTWVTSNAYSSPSIVLAFHNSQDGSRNILDDFREAYYWLSQNTADDARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSTEEKSYEIMTSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIKESDYFTDRGEFRVDAEGAPALLNCLMYKLSYYRFGELKLDYRGPSGYDRTRNAVIGNKDFD-LTYLEEAYTTEHWLVRIYRVKKPHEFNRPSLKTKERTIPPAN-FISRKNSKRRKGYIRNRPVVVKGKRTLK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39007-1", "uniprot_id": "STT3_YEAST", "id": "P39007-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3", "aln": "-------MGSDRSCVLS-------------------------------------------------VFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRATKYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWLGLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPGYISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMVSAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPFVGFLPIRSNDHMAALGVFGLIQIVAFGDFVKGQISTAKFKVIMMVSLFLILVLGVVGLSALTYMGLIAPWTGRFYSLWDTNYAKIHIPIIASVSEHQPVSWPAFFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSVLCSYFAGVMVRLMLTLTPVICVSAAVALSKIFDIYLDFKTSDR----------------------------------KYAIKPAALLA---KLIVSGSFIFYLYLFVFHSTWVTRTAYSSPSVVLPSQT-PDGKLALIDDFREAYYWLRMNSDEDSKVAAWWDYGYQIGGMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDYVLVIFGGLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDARASETMRNSLLYKMSYKDFPQL---FNGGQATDRVRQQMITPLDVPPLDYFDEVFTSENWMVRIYQLKKDDAQGR---------TLRDVGELTRSSTKTRRSIKRPELGLRV---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :.:::.:.*:. : *.:********:***************:* ::..:.:*:******:*:******:.***:***** *:. * *. *.:.:.**::**::** ***:*: :*: :*:*: . .***:** ****************:***.*** * .*: :*::: ****:: : ...* ************** ********:*::* *** :: :*:*:* :* : ********* ***:.:**** *** *: * .::. :: :*: ::::. * .:.: ** * :***:*********.*****************.:* :**** *:*: **.*:: : :::**:*** *:: . ****************:*: :.:*:* ::: :* . .* . : :. * ** .:: * :*..*.**** .******:**. . **. ::*******:** *: :.::* :********.***:************:***:*****:* * :*:*: ***********:**:.**********:**:** *::*:* *::* .**:*** .: :: *.*:**:** * :: :. . **.*: * *. : :::*.:*:*:*:****::* . :::..:* ::. : . . ", "identical_positions": 348, "similar_positions": 213, "identity": "41.78%" }, { "cls_id": "homologset.agr.FB:FBgn0011361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF13-1", "uniprot_id": "D3ZF13_RAT", "id": "D3ZF13-1", "name": "Acyl carrier protein", "aln": "MASRVLCACVRRLPAAFAPLPR-----LPTLALARPLSTILCPEGIWRRTGTLQPTLALAQVPGTVTHLCRQYSDAPPLTLEGIRDRVLYVLKLYDKIDP----EKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR21-1", "uniprot_id": "ACPM_MOUSE", "id": "Q9CR21-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MASRVLCACVRRLPAAFAPLPR-----LPTLALARPLSTTLCPEGIRRRPGALQSALALAQVPGTVTHLCRQYSDAPPLTLDGIKDRVLYVLKLYDKIDP----EKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14561-1", "uniprot_id": "ACPM_HUMAN", "id": "O14561-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MASRVLSAYVSRLPAAFAPLPR-----VRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGRVTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDP----EKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QCE9-1", "uniprot_id": "F1QCE9_DANRE", "id": "F1QCE9-1", "name": "Acyl carrier protein", "aln": "MASRALAQCVRSLARASARLNEGRTACVLLAAAQRPLSSWTCNQRTSR--------TELLRIPSPSVHLCRHYSDAPPLTLDDIQERVLYVLKLYDKINP----DVLKSTSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDGDGEKLMTPEEIVTYIADKKDVYE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94519-1", "uniprot_id": "ACPM_DROME", "id": "Q94519-1", "name": "Acyl carrier protein, mitochondrial", "aln": "MSFTQIARSCSRLAATLAPRRVASG-ILIQSQASRMMHRIAVPSMTSQ--------LSQECRGRWQTQLVRRYSAKPPLSLKLINERVLLVLKLYDKIDP----SKLNVESHFINDLGLDSLDHVEVIMAMEDEFGFEIPDSDAEKLLKPADIIKYVADKEDVYE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32463-1", "uniprot_id": "ACPM_YEAST", "id": "P32463-1", "name": "Acyl carrier protein, mitochondrial", "aln": "-----MFRSVCRISSRVAPSAY-----------RTIMGRSVMSN----------------------TILAQRFYSAN-LSKDQVSQRVIDVIKAFDKNSPNIANKQISSDTQFHKDLGLDSLDTVELLVAIEEEFDIEIPDKVADELRSVGETVDYIASNPDAN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. * : . * ::: *: . : :**: *:* :** .* . :. ::* :******** **:::*:*:**.:**** .::* : : *:*.: *. ", "identical_positions": 33, "similar_positions": 38, "identity": "20.0%" }, { "cls_id": "homologset.agr.FB:FBgn0011455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A565-1", "uniprot_id": "D4A565_RAT", "id": "D4A565-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "MKLASTRRCPHSTWPSRHSPSLVDCPSRLPLPTLLPSVAVVAMAAMSLLQRASVAALTALSGRRAGTRLGVGSFLTRSFPKTVAPVRHSGDHGKRLFVIKPSLYYDARFLRLMKFYLLLTGIPVIIGITLVNIFIGEAELAEIPEGYIPEHWEYYKHPISRWIARTFYDGPEKNYEKTLAILQIESEKADLRLKELEVRRLMRARGDGPWYQYPTPEKEFIDYSPKSTPDN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQH3-1", "uniprot_id": "NDUB5_MOUSE", "id": "Q9CQH3-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "------------------------------------------MAAMSLLQRASVSALTALSCRRAGPRLGVGSFLTRSFPKTVAPVRHSGDHGKRLFVVKPSLYYDARFLRLMKFYLMLTGIPVIIGITLVNIFIGEAELAEIPEGYIPEHWEYYKHPISRWIARNFYDGPEKNYEKTLAILQIESEKAELRLKEQEVRRLMRARGDGPWYQFPTPEKEFIDHSPKATPDN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43674-1", "uniprot_id": "NDUB5_HUMAN", "id": "O43674-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "------------------------------------------MAAMSLLRRVSVTAVAALSGRPLGTRLGFGGFLTRGFPKAAAPVRHSGDHGKRLFVIRPSRFYDRRFLKLLRFYIALTGIPVAIFITLVNVFIGQAELAEIPEGYVPEHWEYYKHPISRWIARNFYDSPEKIYERTMAVLQIEAEKAELRVKELEVRKLMHVRGDGPWYYYETIDKELIDHSPKATPDN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTU2-1", "uniprot_id": "Q9VTU2_DROME", "id": "Q9VTU2-1", "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "aln": "---------------------------------------------MVGWSRLLSPAAKFASYRAVLQEPACRNALHQQLR------RMGGDHGHHQMIIKPSRFQWDKFKDLLHFYVMLGVIPVTALVLYANIFVGPAQLAEIPEGYEPKHWEYEKHPISRFISRYILNSDQQNYEKSLHYLYEENEKAQIRLLEDEVRRKMSERNDYQAYYYRPSVAKYHRISKEAADELEALRGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .* * * . . . * : : * .****:: ::::** : :* *::**: * *** : .*:*:* *:******** *:**** ******:*:* : :. :: **::: * * ***::*: * ***: * *.* * : . : * ::: : ", "identical_positions": 63, "similar_positions": 46, "identity": "26.58%" }, { "cls_id": "homologset.agr.FB:FBgn0011474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEB9-1", "uniprot_id": "D3ZEB9_RAT", "id": "D3ZEB9-1", "name": "N-lysine methyltransferase KMT5A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARGRKMCKPRAVEAAAAAVAATAPGPEMVERRGPGRPR--------------SDGENVFAGQSKIYAYMSPNKCSGMRSPLQEENSVAHHEVKCPGKPLAGIYRKR---EEKRNAGNVIRSAVKSEEQKSKDTRRGPLAPFPNQKPEATEPPKTPPPSCDSTSVAVAKQALKKPLKGKQAPRKKS---QGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKKIDELIESGKEEGMKIDLIDGKGRGVIATKRFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATQETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAYPWLKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2YDW7-1", "uniprot_id": "KMT5A_MOUSE", "id": "Q2YDW7-1", "name": "N-lysine methyltransferase KMT5A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARGRKMCKPRAVEAAAAAVAATAPGPEMVEQRGPGRPR--------------SDGENVFAGQSKIYAYMSPNKCSAMRSPLQEENSVAHHEVKCPGKPLAGIYRKR---EEKRNTGNVIRSAVKSDEQKSKDTRRGPLAPFPNQKSEAAEPPKTPPPSCDSTNVAVAKQALKKSLKGKQAPRKKS---QGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKK-NELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYVQDPSTGCYMYYFQYLSKTYCVDATQETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAYPWLKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQR1-1", "uniprot_id": "KMT5A_HUMAN", "id": "Q9NQR1-1", "name": "N-lysine methyltransferase KMT5A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEGGAAAALVAAAAAAAAAAAAVVAGQRRRRLGRRARCHGPGRAAGGKMSKPCAVEAAAAAVAATAPGPEMVERRGPGRPR--------------TDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKR---EEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKA---QGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q071E0-1", "uniprot_id": "KT5AA_DANRE", "id": "Q071E0-1", "name": "N-lysine methyltransferase KMT5A-A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPAVNEIKVQTWRR-----------DQRGECPRRSAQCRLFSCAHRECAPAARSLENRGPENRT--------------ARPEATMSGD------VLCNGHSAFHRLLKHSSSRTHEAL---------VVKII---QENKNTP---LFCTAPEPRRDSGVNGEFLLNSAELQDEQTLPLHCIHSAADITSSKHRKPARR---KVKRSTKRAA---ESKSPANRKVTDYFPIRRSSRKSKSELKYEEKQHIDTLISNGIEDGMMVRFIEGKGRGVFATQPFQKGQYVVEYHGDLLQITDAKQREALYAQDPSTGCYMYYFQYLSKTYCVDATKESDRLGRLINHSKNGNCQTKLHAIAGKPHLILVASRDIQEGEELLYDYGDRSKSSIEAHPWLKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFK6-1", "uniprot_id": "KMT5A_DROME", "id": "Q9VFK6-1", "name": "Histone-lysine N-methyltransferase Set8", "aln": "MIMVRRRQRPAKEAASSSSGGASSGSGIPVDQALPLNVAGNLLEDQYFASPKRKDCRLMKVTQNGQLPEATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTEEQLNLGNQELKLDDEELNGQIKLDDEVLKLADKQINENLPFADEVDAKAEQKLMDEELQQVVEELLFDGSSRASSNSPFYQHDMDVMQEIQQTPEIPHIKKVTEPLEGLGSLADFQTHRSALRDSHSSTHSSSTDNIFLQEPVLTLDIDRTPTKASSIKINRSFELAGAVFSSPPSVLNACLNGRFNQIVSLNGQKEALDLPHFDLDQHDSSSCDSGVACGLTANTESPAGQPRRRKPATPHRILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAPYQPQLQKPPSQQQQQQQDDIVVVLDDDDDEGDDEDDVRALIKAAEERENQNKAPATANSNKAGMKTMLKPAPVKSKTKSKGPTKGQPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEEWMRGLEQAVLEERCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDYGDRSKESLLHHPWLAF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . ..* * : . . . . : .* : : ::::: : . . * .: : : . . . . : * * ..: . . : **::**::*:*** **:*: :: * : : : . :*: : : ******.* : *.:.::**** ***:.* :* :** *. * .:*******:: *: **:*** ::.:********: ** **: * ***:*:*. ** **** ******** *: :*** .", "identical_positions": 89, "similar_positions": 86, "identity": "12.88%" }, { "cls_id": "homologset.agr.FB:FBgn0011476", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8B0-1", "uniprot_id": "D3Z8B0_RAT", "id": "D3Z8B0-1", "name": "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "aln": "--------------MVAPAVLR-----ALRKNKTLRYGVPMLLLVVGGSFGLREFSQIRYD-AVTIKIDPELEKKLKV---NK--ITLESEYEKIKDSTFENWKNIRGPRPWEDPQLLQGRNPETLKPKTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR63-1", "uniprot_id": "COX16_MOUSE", "id": "Q9CR63-1", "name": "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "aln": "--------------MIAPAVLR-----ALRKNKTLRYGVPMLLLVVGGSFGLREFSQIRYD-AVTIKIDPELEKKLKV---NK--ITLESEYEKIKDSTFENWKNIRGPRPWEDPQLLQGRNPETLKPKTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0S2-1", "uniprot_id": "COX16_HUMAN", "id": "Q9P0S2-1", "name": "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "aln": "--------------MFAPAVMR-----AFRKNKTLGYGVPMLLLIVGGSFGLREFSQIRYD-AVKSKMDPELEKKLKE---NK--ISLESEYEKIKDSKFDDWKNIRGPRPWEDPDLLQGRNPESLKTKTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF98-1", "uniprot_id": "Q9VF98_DROME", "id": "Q9VF98-1", "name": "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "aln": "--------------MSLVDKLN-----YYSTRKSFKYGIPFLIMMVAGSFGLQQFSNLRYQYAKKQPVTPEEMKKYGVSMKNRKDVTLESEYDKVKSVDIENWENKRGPRPWEE----QEDQPTTAKH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47081-1", "uniprot_id": "COX16_YEAST", "id": "P47081-1", "name": "Cytochrome c oxidase assembly protein COX16, mitochondrial", "aln": "MSFSGKKFRSRRQQLVYEASLAGRYKKALSKHPFLFFGLPFCATIVLGSFWLSSFTAIKYEQGDRKVQEINEEDILKIR-KNQREFDIKEEYYRLQGLSEEDWEPVRVAR--------LKDESENVW----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. : :*:*: :* *** * .*: ::*: . : . *: . ::.** :::. ::*: * .* :. . ", "identical_positions": 15, "similar_positions": 33, "identity": "11.45%" }, { "cls_id": "homologset.agr.FB:FBgn0011481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BWW4-1", "uniprot_id": "SSBP3_HUMAN", "id": "Q9BWW4-1", "name": "Single-stranded DNA-binding protein 3", "aln": "MFAKGKGS--AVPSDG-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYS-----------------AAAAPSP-VLGNIPPNDG----MPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMS-PRYAGGPRPPIRMGNQ-PPGGVPGTQPLLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS--GMRPPPNSLG--PAMPGINMG-PGAGRPWPNPNSANS-IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTN------SSDNIYTMINPVPPGGSRSN----------------------------FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP--KNSPNNISGISNPPGTPRDDGELG------GNFLHS------------------------FQNDNYSPSMTMSV---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D032-1", "uniprot_id": "SSBP3_MOUSE", "id": "Q9D032-1", "name": "Single-stranded DNA-binding protein 3", "aln": "MFAKGKGS--AVPSDG-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYS-----------------AAAAPSP-VLGNIPPNDG----MPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMS-PRYAGGPRPPIRMGNQ-PPGGVPGTQPLLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS--GMRPPPNSLG--PAMPGINMG-PGAGRPWPNPNSANS-IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTN------SSDNIYTMINPVPPGGSRSN----------------------------FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP--KNSPNNISGISNPPGTPRDDGELG------GNFLHS------------------------FQNDNYSPSMTMSV---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R050-1", "uniprot_id": "SSBP3_RAT", "id": "Q9R050-1", "name": "Single-stranded DNA-binding protein 3", "aln": "MFAKGKGS--AVPSDG-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYS-----------------AAAAPSP-VLGNIPPNDG----MPGGPIPPGFFQ---------------------------PFMS-PRYAGGPRPPIRMGNQ-PPGGVPGTQPLMPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS--GMRPPPNSLG--PAMPGINMG-PGAGRPWPNPNSANS-IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTN------SSDNIYTMINPVPPGGSRSN----------------------------FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDINGLP--KNSPNNISGISNPPGTPRDDGELG------GNFLHS------------------------FQNDNYSPSMTMSV---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81877-1", "uniprot_id": "SSBP2_HUMAN", "id": "P81877-1", "name": "Single-stranded DNA-binding protein 2", "aln": "MYGKGKSNSSAVPSDS-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYS-----------------AAAAPSP-VLGNIPPGDG----MPVGPVPPGFFQ---------------------------PFMS-PRYPGGPRPPLRIPNQ-ALGGVPGSQPLLPSGMDPT-RQQGHPNMGGPMQRMTPPRGMVPLGP--QNYGG--AMRPPLNALGG-PGMPGMNMG-PGGGRPWPNPTNANS-IPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTN------SGDNMYTLMNAVPPGPNRPN----------------------------FPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSIS--KNSPNNMS-LSNQPGTPRDDGEMG------GNFLNP------------------------FQSESYSPSMTMSV---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CYZ8-1", "uniprot_id": "SSBP2_MOUSE", "id": "Q9CYZ8-1", "name": "Single-stranded DNA-binding protein 2", "aln": "MYGKGKSNSSAVPSDS-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYS-----------------AAAAPSP-VLGNMPPGDG----MPVGPVPPGFFQ---------------------------PFMS-PRYPGGPRPPLRIPNQ-ALGGVPGSQPLLPSGMDPT-RQQGHPNMGGPMQRMTPPRGMVPLGP--QNYGG--AMRPPLNALGG-PGMPGMNMG-PGGGRPWPNPTNANS-IPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTN------SGDNMYTLMNAVPPGPNRPN----------------------------FPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSIS--KNSPNNMS-LSNQPGTPRDDGEMG------GNFLNP------------------------FQSESYSPSMTMSV---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M8F8-1", "uniprot_id": "A0ABK0M8F8_RAT", "id": "A0ABK0M8F8-1", "name": "", "aln": "MFLPYLTTSGVLKVEPPLTTWNQPQLCYLCVFFSSIHWLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYS-----------------AAAAPSP-VLGNMPPGDG----MPVGPVPPGFFQ---------------------------PFMS-PRYPGGPRPPLRIPNQ-ALGGVPGSQPLLPSGMDPT-RQQGHPNMGGPMQRMTPPRGMVPLGP--QNYGG--AMRPPLNALGG-PGMPGMNMG-PGGGRPWPNPTNANS-IPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTN------SGDNMYTLMNAVPPGPNRPN----------------------------FPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSIS--KNSPNNMS-LSNQPGTPRDDGEMG------GNFLNP------------------------FQSESYSPSMTMSV---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B9V2-1", "uniprot_id": "A0A8M3B9V2_DANRE", "id": "A0A8M3B9V2-1", "name": "", "aln": "MYAKGKSS---VPSDS-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYS-----------------AAATQSP-VIG-SPPGDG----MPL---PPGFFQ---------------------------QFMS-PRYPGGPRGSLRIPNQ-ALG--PGNQPLLPSGMDPT-RQPGHPSLSGPMQRMTP-RGMVPIGP--QNYGG--GMRPPLNALVG-PGMPGINMG-PAGGRPWPNPPNNNSQIPYSSASPGSYSGPPAGGGPPGTPIMPSPAESNN------SSDNLY-MISSVPPNGTRPN----------------------------FPLGSGADGPIGSMAGMEPHHMNGSLGSGDIESLP--KSSPGNLS-MNNQPGTPRDDGEMS------GNFLNP------------------------FQSESYSPNMTMSV---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9BWG4-1", "uniprot_id": "SSBP4_HUMAN", "id": "Q9BWG4-1", "name": "Single-stranded DNA-binding protein 4", "aln": "MYAKGGKGS-AVPSDS-----------------QAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYS-----------------AAAAPSP-VMGSMAPGDT----MAAGSMAAGFFQGPPGSQPSPHNPNAP-----MMGPHGQPFMS-PRFPGGPRPTLRMPSQ-PPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGP--QSYGG--GMRPPPNSLAG-PGLPAMNMG-PGVRGPWASP-SGNS-IPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTN------SSENMYTIMNPIGQGAGRAN----------------------------FPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAVAGLSNAPGTPRDDGEMAA----AGTFLHP------------------------FPSESYSPGMTMSV---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V8L4-1", "uniprot_id": "G3V8L4_RAT", "id": "G3V8L4-1", "name": "", "aln": "MYGKASKG--CAPSDG-----------------QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPDRREACEHSSEAKVFQDYSA----------------AAAAPSP-VMGTLAPNDA----MAAGPVAPGFFQ---------------------------PFIS-PRFPGGARPILRMPGQ-PPVGLPGSQHLIPGAMDPSPRAQGHPSLGGPMQRVTPPRGMASVGP--QGFGT--GMRPPPNSLATSQILPSMNMG-PGVRGPWASP-SGNS-IPYSSSSPGSYSGPTGGGGAPGTPIMPSPGDSTN------SSENMYTIMNPIGPGAGRANVSGGRCASPDGDLAGGGRPEPHAALCPQFPLGPSPEGPMASMSTMEPHHVNGSLGSGDMDGLP--KNSPGAVGGLNNAPGTPRDDGEMAA----AGTFLHP------------------------FPSESYSPGMTMSV---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4KGW6-1", "uniprot_id": "A0A0B4KGW6_DROME", "id": "A0A0B4KGW6-1", "name": "", "aln": "MYGKSKTS--AVPSDA-----------------QAREKLALYVYEYLLHVGAQKAAQTFLSEIRWEKNITLGEPPGFLHTWWCVFWDLYCAAPERRDQCDHSSEAKAFHDYGFVSSGYGVNGIGPGGPHNAGGPAPSPLGQMPPGGDGGPMGPGGPMGPNFFPNSTMRPSPPTHASSPQPPPSQMMPGQPPFMGGPRYPGGPRPGVRMQGMGNEFNGPPGQPMMPNSMDPT-RPGGG--MGPMNPRMNPPRGPGGMGP--MGYGGPGGMRGPAPGPGG---MPPMGMGGAGGRPPQWQPNASAPLNAYSSSSPGNYGPGSNGPPGPGTPIMPSPQDNTQGGPVGGPGDSMYALMKPEFPMGGGPDGGG-------------------------GGGGPGGMGPMGGGPNSMGPVLNGGGGP-DGSGLDGMKNSP-----ANGGPGTPREDSGSGMGDYNLGGFGGPGENDQTESAAILKIKESMHEEAKRFEKDTDHPDYFMPXQHHQQQQQQHQQHLNTVAAAVAAVVAAAASNGSAAGSSSAASIAAAALGAAASNLLSNGNNNF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : .: . ***********:****:************************:*************:**: *:**.***.*:**. *. :* :* .*.. . ..** *:. **:.**.* :*: . * * ::*..*:*: * * :. *:.* ** :** .:* .** * . :* :.** .. * .* . .***:***.* . * ********* :..: ..:.:* ::.. .: *.. **:.. :**. *. * ..: *.** .. *****:*. . * * . * .:. *. *. ", "identical_positions": 138, "similar_positions": 96, "identity": "24.34%" }, { "cls_id": "homologset.agr.FB:FBgn0011509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZX7-1", "uniprot_id": "SRPRB_RAT", "id": "Q4FZX7-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MASANTRRVGDG--AGGAFQPYLDSLRQELQQRDPTLLSVAVAVLAVLLTLVFWKFIWSRKSSQRAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRLQFLDRFKSSAR---AVVFVVDSATFQREVKDVAEFLYQVL-IDSMALKNTPAFLVACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS-AAPSTL-----DSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDAGSADVQDLEKWLAKIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47758-1", "uniprot_id": "SRPRB_MOUSE", "id": "P47758-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MASANTRRVGDG--AGGAFQPYLDSLRQELQQRDPTLLSVAVALLAVLLTLVFWKFIWSRKSSQRAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRFQLLDRFKSSAR---AVVFVVDSAAFQREVKDVAEFLYQVL-IDSMALKNSPSLLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS-AAPSTL-----DSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDTGSADIQDLEKWLAKIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5M8-1", "uniprot_id": "SRPRB_HUMAN", "id": "Q9Y5M8-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MASADSRRVADGGGAGGTFQPYLDTLRQELQQTDPTLLSVVVAVLAVLLTLVFWKLIRSRRSSQRAVLLVGLCDSGKTLLFVRLLTGLYRDTQTSITDSCAVYRVNNNRGNSLTLIDLPGHESLRLQFLERFKSSAR---AIVFVVDSAAFQREVKDVAEFLYQVL-IDSMGLKNTPSFLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS-AAPSTL-----DSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSN9-1", "uniprot_id": "Q9VSN9_DROME", "id": "Q9VSN9-1", "name": "Signal recognition particle receptor subunit beta", "aln": "MDKLNEN----------------ARQRKQIKLGEIDTGPIIVALLLGFIAVAIFVILRRRSAGRKDFLLTGLSESGKSAIFMQLIHGKFPATFTSIKENVGDYRTG---SASARLVDIPGHYRVRDKCLELYKHRAK---GIVFVVDSVTAHKDIRDVADFLYTIL-SDSATQPCS--VLVLCNKQDQTTAKSAQVIKSLLESELHTVRDTRSRKLQSVG-----DEDGSKSITLGKPGRDFEFSHIAQNIQFAEASAK-------DTELDPLTDWLARLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36057-1", "uniprot_id": "SRPB_YEAST", "id": "P36057-1", "name": "Signal recognition particle receptor subunit beta", "aln": "------------------------MLSNTLIIACLLVIGTTIALIAVQKASSKTGIK--QKSYQPSIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQEP----LSAADYDGSGVTLVDFPGHVKLRYKLSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFTARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLEASVVAFEGSIN-------KRKISQWREWIDEKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:: : : : : : .::.* :***: :: * . * .* . . . *:*:*** :* : : * *: .::*:***.. :.: .*:** :* . .*: ***.: *:... *:. **.*::.: *. .. :. . . : : *:*::: .: * * : . .:. .*: . ", "identical_positions": 39, "similar_positions": 80, "identity": "13.88%" }, { "cls_id": "homologset.agr.FB:FBgn0011555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36376-1", "uniprot_id": "KLK12_RAT", "id": "P36376-1", "name": "Glandular kallikrein-12, submandibular/renal", "aln": "----------------------------------------------------------MWLQILFLVLSVGRIDAAP----------------------PGQSRVVGGYKCEKNSQPWQVAV---INRYLCGGVLIDPSWVITAAHCYSHN--------YHVLLGRNNLFKDEPFAQYRVVN-QSFPHPDYNPFFMKNHTLFPGDDHSNDLMLLHLSEPADITDG----------------------VKVIDLPTEEPKVGSTCLASGWSSTK----------PLEWEFPDDLQCVNINILSNEKCIKAHTQ--------MVTDVMLCAGELEGGKDTCNGDSGGPLLCDG-----VLQGITSWSSVPCGETNRPAIYTKLIKFTSWIKEVMKENS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M040-1", "uniprot_id": "A0ABK0M040_RAT", "id": "A0ABK0M040-1", "name": "tissue kallikrein", "aln": "MRVGAQNPPQSARAGPWPASGCQQGRGGAGGELGVFKGSPRKLLSSKITTCCPWTPDTMWFLILFLALSLGQIDAAP----------------------PGQSRVVGGFKCEKNSQPWQVAV---INEDLCGGVLIDPSWVITAAHCYSDN--------YHVLLGQNNLSED---VQHRLVS-QSFRHPDYKPFLMRNHTRKP-KDYSNDLMLLHLSEPADITDG----------------------VKVIDLPTKEPKVGSTCLVSGWGSTN----------PSEWEFPDDLQCVNIHLLSNEKCIKAYKE--------KVTDLMLCAGELEGGKDTCRGDSGGPLICDG-----VLQGITSWGSVPCGEPNKPGIYTKLIKFTSWIKEVMKKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00759-1", "uniprot_id": "KLK2_RAT", "id": "P00759-1", "name": "Tonin", "aln": "----------------------------------------------------------MWLQILSLVLSVGRIDAAP----------------------PGQSRIVGGYKCEKNSQPWQVAV---INEYLCGGVLIDPSWVITAAHCYSNN--------YQVLLGRNNLFKDEPFAQRRLVR-QSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGG----------------------VKVIDLPTKEPKVGSTCLASGWGSTN----------PSEMVVSHDLQCVNIHLLSNEKCIETYKD--------NVTDVMLCAGEMEGGKDTCAGDSGGPLICDG-----VLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "----------------------------------------------------------MWFLILFLALSLGQIDAAP----------------------PGQSRVVGGYNCETNSQPWQVAV---IGTTFCGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLVKDEPFAQRRLVS-QSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGG----------------------VKVIDLPTEEPKVGSICLASGWGMTN----------PSEMKLSHDLQCVNIHLLSNEKCIETYKN--------IETDVTLCAGEMDGGKDTCTGDSGGPLICDG-----VLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36374-1", "uniprot_id": "KLK6_RAT", "id": "P36374-1", "name": "Prostatic glandular kallikrein-6", "aln": "----------------------------------------------------------MWLLILFLILSLGWNDAAP----------------------PGQSRIIGGFNCEKNSQPWQVAVYH-FNEPQCGGVLIHPSWVITAAHCYSVN--------YQVWLGRNNLLEDEPFAQHRLVS-QSFPHPGFNLDIIKNHTRKPGNDYSNDLMLLHLKTPADITDG----------------------VKVIDLPTEEPKVGSTCLTSGWGSIT----------PLKWEFPDDLQCVNIHLLSNEKCIKAYND--------EVTDVMLCAGEMDGGKDICKGDSGGPLICDG-----VLQGITSWGSMPCGEPNKPSVYTKLIKFTSWMKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R7G1-1", "uniprot_id": "M0R7G1_RAT", "id": "M0R7G1-1", "name": "", "aln": "----------------------------------------------------------MWLLLAFILL----VSAAQ----------------------DGD-KVLEGEECVPHSQPWQVALFE-RGRFNCGAFLISPHWVLTAAHCQTRF--------MRVRLGEHNLRKFDGPEQLRSVS-RIIPHPGY-----------EARTHRHDIMLLRLFRPARLTPQ----------------------VRPVALPTRCPLLGEDCVVSGWGLLSDNSPGATGSHKSQVRLPDTLHCANISIISEASCNKDYPG--------RVLPTMVCAGVEGGGTDSCEGDSGGPLVCGG-----ALQGIVSWGDVPCDTTTKPGVYTKVCSYMDWIRKNMRRN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "---------------------------------------------------MMVTARTPWGWFLGCLILEVTGASAS----------------------SVSSRIIQGQDCSPHSQPWQAALFS-EDGFFCSGVLVHPQWVLSAAHCLQES--------YIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFN-----------DPSFANDLMLIKLNESVIESNT----------------------IRSIPVATQCPTPGDTCLVSGWGQLK------------NGKLPSLLQCVNLSVASEETCRLLYDP--------VYHLSMFCAGGGQDQKDSCNGDSGGPIVCNR-----SLQGLVSMGQGKCGQPGIPSVYTNLCKFTNWIQTIIQTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "-------------------------------------------------------MKWCWGPVLLIAGATVLMEGLQAAQRACGQRG-------------PGPPKPQEGNTVPGEWPWQASVRR-QGAHICSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREGLSPGAEEVGVAALQLPRAYN------------HYSQGSDLALLQLAHPTTHT------------------------PLCLPQPAHRFPFGASCWATGWDQDTS-------------DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASS-CAQEDAPVLLTNTAAHSSWLQARVQG----AAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR-------QAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGG----DGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEP-------EPEAEPGSCLANISQPTSC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "-------------------------------------------------------MRQSWRPELLIVGAVVVIEGLQAAQRACGQRG-------------PGPPEPQEGNTLPGEWPWQASVRR-QGVHICSGSLVADTWVLTAAHCFEKMATAELS-SWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYN------------HYSQGSDLALLQLTHPTVQT------------------------TLCLPQPTYHFPFGASCWATGWDQNTS-------------DVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSK-CAQEDTPVLLTDMAVHSSWLQAHVHE----AAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGR-------QTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLGPMACSRQHAAPGG----TGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLDWQVYFAEEP-------EPEAETGSCLVNSSQPASC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K2P9-1", "uniprot_id": "POLS2_RAT", "id": "Q5K2P9-1", "name": "Polyserase-2", "aln": "------------------------------------------------------MSHHLFLPVVIMVVSPIPPGAFQDSVVSPTQGEFEDLDCGDCGRPEPSSRIVGGSDAHPGTWPWQVSLHQ-GGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVHSQDGPLEGAHMRSVATILIPDNYS------------TVELGADLALLRLASPAKLGPSVRGADLALLRLASPAKLGPSVRPVCLPRASHLFAHGTACWATGWGDVQEA---------VPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYPAGRRDTCQGDSGGPLVCED-GGRWFLAGITSFGFG-CGRRNRPGVFTAVAPYESWIREHVMGSEPGPVFPSQLQKPQSGPWEPREENCTFAQPECGKAPRPGTWPWEAQVTVPGSTPCYGALVSDRWVLAPASCFLDS------PHDFETWRVLLPSRPEEERVARLVAHENASR-DFASDLALLQLRTRVNLTAAPSAVCLPHHEHYFLPGSHCRLARWGRGELAPGSSAQLEAQLLNGWWCHCLYGRQGETVPRPGDPPHLLCPAYQEEEEAGLCWVDSSWSLLCREEGTWFLAGYRTLSDGCLR---PRAFSPMQTHGPWIRHVTQGAYLEDQLTWDWGPEGEETEKQTCPTHTEHGACGLRPKSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSTTVPYIEVYLGRAGVSSLPQGHQVSRSVVSIRLPRHLGLRPPLALLELNSRVEPSPSALPICLHPGGIPSGASCWVLGWKNPQDRVPVVAAVSILTPRLCHCLYPGILTPGTFCVLYSEGQEDRCEVTSAPPLLCQTEEGPWVLVGMAVRGNRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDLCPQDLAGSASSPKVTALLLLLLLAPLIPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "------------------------------------------------------MSPHLFLPVVVLVVSPTP-GAFQDSAVSPTQGEFEDLDCG---RPEPSSRIVGGSDAHPGTWPWQVSLHH-GGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYS------------RVELGADLALLRLASPAKLG--------------------PSVKPVCLPRASHLFAHGTACWATGWGDVQES---------DPLPVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCED-GGRWFLAGITSFGFG-CGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDS------LHDFETWRVLLPSRPEEKRVVRLVAHENASR-NFASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLR---PRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALP--LLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "------------------------------------------------------MARHLLLPLVMLVISPIP-GAFQDSALSPTQEEPEDLDCG---RPEPSARIVGGSNAQPGTWPWQVSLHH-GGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYS------------QVELGADLALLRLASPASLG--------------------PAVWPVCLPRASHRFVHGTACWATGWGDVQEA---------DPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFGFG-CGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASW-DNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFL--LLLTLLIQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42278-1", "uniprot_id": "TRYT_DROME", "id": "P42278-1", "name": "Trypsin theta", "aln": "-------------------------------------------------------MHRLVVLLVCLAVGSACAGTVGVSNGDP---------------FEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSLINEDTVVTAAHCLVGR-------KVSKVFVRLGSTLYNEGGIVVAVRELAYNEDYN------------SKTMEYDVGILKLDEKVKETEN----------------------IRYIELATETPPTGTTAVVTGWGSKCYF---------WCMTLPKTLQEVYVNIVDWKTCASDEYKYG-----EIIYDSMVCAYEKK--KDACQGDSGGPLAVGN-----TLVGIVSWGYA-CASNLLPGVYSDVPALRKWILNASETL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6TEK4-1", "uniprot_id": "VKOR1_RAT", "id": "Q6TEK4-1", "name": "Vitamin K epoxide reductase complex subunit 1", "aln": "---------------------------------------------------------------------------------------------------------MGTTWRSPGR----------LRLALCLAGLALSLYALHVKAARARN---------------EDYRALCDVGTAISCSRVFSSRWG--------------RGFGLVEHVLGADSILNQS------------------------NSIFGCMFYTIQLLLGCLRGRWASIL-------------LILSSLVSVAGSLYLAWILFFVLYDF------------CIVC-------ITTYAINAG--------------LMLLSFQKVPEHKVKKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * .: . . :: . . * . : .* ::* : * * ", "identical_positions": 7, "similar_positions": 15, "identity": "0.73%" }, { "cls_id": "homologset.agr.FB:FBgn0011556", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2L4Q9-1", "uniprot_id": "PRS53_HUMAN", "id": "Q2L4Q9-1", "name": "Serine protease 53", "aln": "-------------------------------------------------------MKWCWGPVLLIAGATVLMEGLQAAQRACGQRG-------------PGPPKPQEGNTVPGEWPWQASVRRQGAHI--------CSGSLVADTWVLTAAHCFEKAAATELN-SWSVVLGSLQREGLSPGAEEVGVAALQLPRAYN-----------HYSQGSDLALLQLAHPTTHT------------------------PLCLPQPAHRFPFGASCWATGWDQDTS-------------DAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQ-PGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASS-CAQEDAPVLLTNTAAHSSWLQARVQG----AAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGR-------QAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGG----DGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEP-------EPEAEPGSCLANISQPTSC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "-------------------------------------------------------MRQSWRPELLIVGAVVVIEGLQAAQRACGQRG-------------PGPPEPQEGNTLPGEWPWQASVRRQGVHI--------CSGSLVADTWVLTAAHCFEKMATAELS-SWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYN-----------HYSQGSDLALLQLTHPTVQT------------------------TLCLPQPTYHFPFGASCWATGWDQNTS-------------DVSRTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQ-PGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSK-CAQEDTPVLLTDMAVHSSWLQAHVHE----AAFLVQAPGVVKMSDENSCVACGSLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGR-------QTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLGLTQK-AGINYPQTVPVTVLGPMACSRQHAAPGG----TGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISNLDWQVYFAEEP-------EPEAETGSCLVNSSQPASC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K2P9-1", "uniprot_id": "POLS2_RAT", "id": "Q5K2P9-1", "name": "Polyserase-2", "aln": "------------------------------------------------------MSHHLFLPVVIMVVSPIPPGAFQDSVVSPTQGEFEDLDCGDCGRPEPSSRIVGGSDAHPGTWPWQVSLHQGGGHI--------CGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVHSQDGPLEGAHMRSVATILIPDNYS-----------TVELGADLALLRLASPAKLGPSVRGADLALLRLASPAKLGPSVRPVCLPRASHLFAHGTACWATGWGDVQEA---------VPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYP-AGRRDTCQGDSGGPLVCED-GGRWFLAGITSFGFG-CGRRNRPGVFTAVAPYESWIREHVMGSEPGPVFPSQLQKPQSGPWEPREENCTFAQPECGKAPRPGTWPWEAQVTVPGSTPCYGALVSDRWVLAPASCFLDS------PHDFETWRVLLPSRPEEERVARLVAHENASR-DFASDLALLQLRTRVNLTAAPSAVCLPHHEHYFLPGSHCRLARWGRGELAPGSSAQLEAQLLNGWWCHCLYGRQGETVPRPGDPPHLLCPAYQEEEEAGLCWVDSSWSLLCREEGTWFLAGYRTLSDGCLR---PRAFSPMQTHGPWIRHVTQGAYLEDQLTWDWGPEGEETEKQTCPTHTEHGACGLRPKSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSTTVPYIEVYLGRAGVSSLPQGHQVSRSVVSIRLPRHLGLRPPLALLELNSRVEPSPSALPICLHPGGIPSGASCWVLGWKNPQDRVPVVAAVSILTPRLCHCLYPGILTPGTFCVLYSEGQEDRCEVTSAPPLLCQTEEGPWVLVGMAVRGNRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDLCPQDLAGSASSPKVTALLLLLLLAPLIPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "------------------------------------------------------MSPHLFLPVVVLVVSPTP-GAFQDSAVSPTQGEFEDLDCG---RPEPSSRIVGGSDAHPGTWPWQVSLHHGGGHI--------CGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYS-----------RVELGADLALLRLASPAKLG--------------------PSVKPVCLPRASHLFAHGTACWATGWGDVQES---------DPLPVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYP-EGRRDTCQGDSGGPLVCED-GGRWFLAGITSFGFG-CGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDS------LHDFETWRVLLPSRPEEKRVVRLVAHENASR-NFASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLR---PRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALP--LLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5K4E3-1", "uniprot_id": "POLS2_HUMAN", "id": "Q5K4E3-1", "name": "Polyserase-2", "aln": "------------------------------------------------------MARHLLLPLVMLVISPIP-GAFQDSALSPTQEEPEDLDCG---RPEPSARIVGGSNAQPGTWPWQVSLHHGGGHI--------CGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYS-----------QVELGADLALLRLASPASLG--------------------PAVWPVCLPRASHRFVHGTACWATGWGDVQEA---------DPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYP-EGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFGFG-CGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASW-DNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFL--LLLTLLIQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36376-1", "uniprot_id": "KLK12_RAT", "id": "P36376-1", "name": "Glandular kallikrein-12, submandibular/renal", "aln": "----------------------------------------------------------MWLQILFLVLSVGRIDAAPPGQS----------------------RVVGGYKCEKNSQPWQVAV--INRYL--------CGGVLIDPSWVITAAHCYSHN--------YHVLLGRNNLFKDEPFAQYRVVNQSFPHPDYNPFFMKNHTLFPGDDHSNDLMLLHLSEPADITDG----------------------VKVIDLPTEEPKVGSTCLASGWSSTK----------PLEWEFPDDLQCVNINILSNEKCIKAHT--------QMVTDVMLCAGEL-EGGKDTCNGDSGGPLLCDG-----VLQGITSWSSVPCGETNRPAIYTKLIKFTSWIKEVMKENS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M040-1", "uniprot_id": "A0ABK0M040_RAT", "id": "A0ABK0M040-1", "name": "tissue kallikrein", "aln": "MRVGAQNPPQSARAGPWPASGCQQGRGGAGGELGVFKGSPRKLLSSKITTCCPWTPDTMWFLILFLALSLGQIDAAPPGQS----------------------RVVGGFKCEKNSQPWQVAV--INEDL--------CGGVLIDPSWVITAAHCYSDN--------YHVLLGQNNLSED---VQHRLVSQSFRHPDYKPFLMRNHTRKP-KDYSNDLMLLHLSEPADITDG----------------------VKVIDLPTKEPKVGSTCLVSGWGSTN----------PSEWEFPDDLQCVNIHLLSNEKCIKAYK--------EKVTDLMLCAGEL-EGGKDTCRGDSGGPLICDG-----VLQGITSWGSVPCGEPNKPGIYTKLIKFTSWIKEVMKKNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00759-1", "uniprot_id": "KLK2_RAT", "id": "P00759-1", "name": "Tonin", "aln": "----------------------------------------------------------MWLQILSLVLSVGRIDAAPPGQS----------------------RIVGGYKCEKNSQPWQVAV--INEYL--------CGGVLIDPSWVITAAHCYSNN--------YQVLLGRNNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGG----------------------VKVIDLPTKEPKVGSTCLASGWGSTN----------PSEMVVSHDLQCVNIHLLSNEKCIETYK--------DNVTDVMLCAGEM-EGGKDTCAGDSGGPLICDG-----VLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "----------------------------------------------------------MWFLILFLALSLGQIDAAPPGQS----------------------RVVGGYNCETNSQPWQVAV--IGTTF--------CGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGG----------------------VKVIDLPTEEPKVGSICLASGWGMTN----------PSEMKLSHDLQCVNIHLLSNEKCIETYK--------NIETDVTLCAGEM-DGGKDTCTGDSGGPLICDG-----VLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36374-1", "uniprot_id": "KLK6_RAT", "id": "P36374-1", "name": "Prostatic glandular kallikrein-6", "aln": "----------------------------------------------------------MWLLILFLILSLGWNDAAPPGQS----------------------RIIGGFNCEKNSQPWQVAVYHFNEPQ--------CGGVLIHPSWVITAAHCYSVN--------YQVWLGRNNLLEDEPFAQHRLVSQSFPHPGFNLDIIKNHTRKPGNDYSNDLMLLHLKTPADITDG----------------------VKVIDLPTEEPKVGSTCLTSGWGSIT----------PLKWEFPDDLQCVNIHLLSNEKCIKAYN--------DEVTDVMLCAGEM-DGGKDICKGDSGGPLICDG-----VLQGITSWGSMPCGEPNKPSVYTKLIKFTSWMKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R7G1-1", "uniprot_id": "M0R7G1_RAT", "id": "M0R7G1-1", "name": "", "aln": "----------------------------------------------------------MWLLLAFILL----VSAAQDGD-----------------------KVLEGEECVPHSQPWQVALFERGRFN--------CGAFLISPHWVLTAAHCQTRF--------MRVRLGEHNLRKFDGPEQLRSVSRIIPHPGY-----------EARTHRHDIMLLRLFRPARLTPQ----------------------VRPVALPTRCPLLGEDCVVSGWGLLSDNSPGATGSHKSQVRLPDTLHCANISIISEASCNKDYP--------GRVLPTMVCAGVE-GGGTDSCEGDSGGPLVCGG-----ALQGIVSWGDVPCDTTTKPGVYTKVCSYMDWIRKNMRRN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42280-1", "uniprot_id": "TRYZ_DROME", "id": "P42280-1", "name": "Trypsin zeta", "aln": "-----------------------------------------------------MSSSWIVGLLAFLVSLVALTQGLPLLEDLDEKSVP-------------DGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVAS----QYKVVAGTN--FQTGSDGVITNVKEIVMHEGYYS----------GAAYNNDIAILFVDPPLPLNNFT---------------------IKAIKLALEQPIEGTVSKVSGWGTTSPG-----------GYSSNQLLAVDVPIVSNELCDQDYEDFG--DETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRD-----ELYGVVSWGNS-CALPNYPGVYANVAYLRPWIDAVLAGL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6TEK4-1", "uniprot_id": "VKOR1_RAT", "id": "Q6TEK4-1", "name": "Vitamin K epoxide reductase complex subunit 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MGTTWRSPGRLRLALCLAGL-------------------------------------------------------ALSLYALHVKAARARNED-----------------------YRALCDVGTAISCSRVFSSRWGRGFG-------------LVEHVLGADSILNQSNSIFGCMFY-------TIQLLLGCLRGRWASILLILSSLVSVAGSLYLAW-----ILFFVLYDFCIVCITTYAINAGLMLLSFQKVPEHKVKKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * .: * : . : *. * : .. . : . . . .*.: : * : ", "identical_positions": 7, "similar_positions": 21, "identity": "0.72%" }, { "cls_id": "homologset.agr.FB:FBgn0011566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3D2-1", "uniprot_id": "D4A3D2_RAT", "id": "D4A3D2-1", "name": "[histone H3]-lysine(4) N-trimethyltransferase", "aln": "-------MTVGSMENVEVFTSEGKGRGLK-ATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQERLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGK--VPNENIRLAARIMWRVER----EGTGLTEGCLVSVDDLQNHVEHFGEE--EQKELRVDVDTFLQYWPPQSQQFSMQY----ISHIFGVINCNGFTLSDQRGLQAVGVGIFPN------------------------------------------------------LGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEG--EELTVSYIDFLHLSEERRQQLKKQYYFDCSCEHCQKGLKDDLFLAVK---------------EDPKPSQEVVKEMTQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIVSEVLSYLQAFEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMYHKMREAALNNQPMQVMAEPSNEPAPALFHKKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97443-1", "uniprot_id": "SMYD1_MOUSE", "id": "P97443-1", "name": "Histone-lysine N-methyltransferase Smyd1", "aln": "-------MTIGSMENVEVFTSEGKGRGLK-ATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECAAIKKYGK--VPNENIRLAARIMWRVER----EGTGLTEGCLVSVDDLQNHVEHFGEE--EQKELRVDVDTFLQYWPPQSQQFSMQY----ISHIFGVINCNGFTLSDQRGLQAVGVGIFPN------------------------------------------------------LGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEG--EELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAK---------------EDPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMYHKMREAALNNQPMQVMAEPSNEPAPALFHKKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NB12-1", "uniprot_id": "SMYD1_HUMAN", "id": "Q8NB12-1", "name": "Histone-lysine N-methyltransferase SMYD1", "aln": "-------MTIGRMENVEVFTAEGKGRGLK-ATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGK--VPNENIRLAARIMWRVER----EGTGLTEGCLVSVDDLQNHVEHFGEE--EQKDLRVDVDTFLQYWPPQSQQFSMQY----ISHIFGVINCNGFTLSDQRGLQAVGVGIFPN------------------------------------------------------LGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEG--EELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKDDLFLGVK---------------DNPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEPSNEPSPALFHKKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PGA4-1", "uniprot_id": "A0A8M1PGA4_DANRE", "id": "A0A8M1PGA4-1", "name": "[histone H3]-lysine(4) N-trimethyltransferase", "aln": "-------MTVEKTDPVEVFGAGLKGRGLR-GTRDLSAGEVVFAEASFAAVVLDSLSLQVCHSCFRRQVNPHRCAQCKFAHYCDRTCQRAAWDEHRKECSAIRNIGK--APNENVRLVARILWRIQK----HTGLVSDSQLTTLDMLEDHLSRMTPE--DLKELKVDVKTFYTYWPKKSKAVGEDY----VSHLFGVISCNGFTLSDQRGLQSVGIGLFPN------------------------------------------------------LCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAG--QELTVSYVDFLSVSTDRQRLLQQQYYFDCKCEHCVNGTKDELMTAVKPT------------EDGKQPSAEVVKQLTDFSLQALVKIEAARAQGNFHEVIRICRECLEKQDPVFADTNVHVLRVLSTASEVLSFLQQFQEAAGYAQRMVDGYMKLYHPNNAQLGMAIMRAGVTHWHAGLIEAAHGLICRAYGILMITHGPHHPISKDLEAMRRQTEMELRMFKQNEHVYHSMREAALTSKPMSVAGEQVQIKA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7M6Z3-1", "uniprot_id": "SMYD2_RAT", "id": "Q7M6Z3-1", "name": "N-lysine methyltransferase SMYD2", "aln": "-------MRAEARGGLERFCSAGKGRGLR-ALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLECSSMVVFGENWNPSETVRLTARILAKQKM----HPERTPSEKLLAVREFESHLDKLDNE--KKDLIQSDIAALHQFYSKHLEFPDHSS----LVVLFAQVNCNGFTIEDEE-LSHLGSAIFPD------------------------------------------------------VALMNHSCCPNVIVTYKG-------------TLAEVRAVQEIHPG--DEVFTSYIDLLYPTEDRNDRLRDSYFFTCECRECTTKDKDKAKVEIR--------------KLSNPPQAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALKYGQKIIKPYSKHYPVYSLNVASMWLKLGRLYMGLENKAAGEKALKKAIAIMEIAHGKDHPYISEIKQEIESH----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R5A0-1", "uniprot_id": "SMYD2_MOUSE", "id": "Q8R5A0-1", "name": "N-lysine methyltransferase SMYD2", "aln": "-------MRAEARGGLERFCSAGKGRGLR-ALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDVECQKEDWPLHKLECSSMVVLGENWNPSETVRLTARILAKQKI----HPERTPSEKLLAVREFESHLDKLDNE--KKDLIQSDIAALHQFYSKYLEFPDHSS----LVVLFAQVNCNGFTIEDEE-LSHLGSAIFPD------------------------------------------------------VALMNHSCCPNVIVTYKG-------------TLAEVRAVQEIHPG--DEVFTSYIDLLYPTEDRNDRLRDSYFFTCECRECTTKDKDKAKVEVR--------------KLSSPPQAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALKYGQKIIKPYSKHYPVYSLNVASMWLKLGRLYMGLENKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRG4-1", "uniprot_id": "SMYD2_HUMAN", "id": "Q9NRG4-1", "name": "N-lysine methyltransferase SMYD2", "aln": "-------MRAEGLGGLERFCSPGKGRGLR-ALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKI----HPERTPSEKLLAVKEFESHLDKLDNE--KKDLIQSDIAALHHFYSKHLGFPDNDS----LVVLFAQVNCNGFTIEDEE-LSHLGSAIFPD------------------------------------------------------VALMNHSCCPNVIVTYKG-------------TLAEVRAVQEIKPG--EEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIR--------------KLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJI7-1", "uniprot_id": "SMY2A_DANRE", "id": "Q5BJI7-1", "name": "N-lysine methyltransferase SMYD2-A", "aln": "-------MKKEGIEGTERFLSPGKGRGLK-AIKHFKVGDLVFACPAYAYVLTVNERGGRCECCFTRKEGLSKCGKCKQAYYCNVECQRGDWPMHKLECSAMCAYGENWCPSETVRLVARIILKQKH----QTERTPSERVLTLRELEAHLDKLDNE--KNEMNDTDIAALHHFYSRHLDFPDNAA----LTELIAQVNCNGFTIEDEE-LSHLGSALFPD------------------------------------------------------VALMNHSCSPNVIVTYKG-------------TVAEVRAVQEINPE--EEIFNSYIDLLYPTEDRIERLKDSYFFNCDCKECTSKSKDEAKMEIRQ-------------KLSIPPEEEEIKQMVIYARNVIEEFRRAKHYKTPSELLEICELSMEKMGAIFAETNVYMLHMMYQAMGVCLYMQDWDGAMKYGEKIIHPYSVHYPPYSLNVASMYLKLGRLYLGLEKRTQGVKALKKALAIMDIAHGKDHPYIDEIKKEMEEQT---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5RGL7-1", "uniprot_id": "SMY2B_DANRE", "id": "Q5RGL7-1", "name": "N-lysine methyltransferase SMYD2-B", "aln": "------MMKAEGIPGIEQFASPGKGRGLR-VSRAYGVGELLFSCPAYSYVLSVGERGLICEQCFTRKKGLAKCGKCKKAFYCNANCQKKNWPMHKLECQAMCAFGENWRPSETVRLVARIIARLKA----QKERSPSEILLLLGEMEAHLEDMDNE--KREMTEAHIAGLHQFYSKHLDFPDHQA----LLTLFSQVHCNGFTVEDEE-LSNLGLAIFPD------------------------------------------------------IALLNHSCSPNVIVTYRG-------------INAEVRAVKDISPG--QEIYTSYIDLLYPTADRLERLRDMYYFSCDCKECTTKSMDVVKMSVR--------------KRSDEIGEKEIKDMVRYARNSMENFRRAKQDKSPTELLEMCELSIDKMSTVFDDSNVYILHMMYQAMGICLFTEDYEGAVRYGEKVIKPFTVLYPAYSMNVASMFLKLGRLYIALDRKLAGIDAFQKALTIMEVVHGKDHTYVTELKQEMRDF----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9CWR2-1", "uniprot_id": "SMYD3_MOUSE", "id": "Q9CWR2-1", "name": "Histone-lysine N-methyltransferase SMYD3", "aln": "----------MEALKVEKFTTANRGNGLR-AVAPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRIAKYCSAKCQKKAWPDHRRECSCLKSCKPR-YPPDSVRLLGRVIVKLMD----EKP-SESEKLYSFYDLESNISKLTED--KKEGLRQLAMTFQHFMREEIQDASQLPPSFDLFEAFAKVICNSFTICNAE-MQEVGVGLYPS------------------------------------------------------MSLLNHSCDPNCSIVFNG-------------PHLLLRAVREIEAG--EELTICYLDMLMTSEERRKQLRDQYCFECDCIRCQTQDKDADMLTGD-------------------------EQIWKEVQESLKKIEELKAHWKWEQVLALCQAIINSNSNRLPDINIYQLKVLDCAMDACINLGMLEEALFYAMRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMKVTHGREHSLIEDLILLLEECDANIRAS---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7B4-1", "uniprot_id": "SMYD3_HUMAN", "id": "Q9H7B4-1", "name": "Histone-lysine N-methyltransferase SMYD3", "aln": "----------MEPLKVEKFATAKRGNGLR-AVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPR-YPPDSVRLLGRVVFKLMD----GAP-SESEKLYSFYDLESNINKLTED--KKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAE-MQEVGVGLYPS------------------------------------------------------ISLLNHSCDPNCSIVFNG-------------PHLLLRAVRDIEVG--EELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGD-------------------------EQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HNI9-1", "uniprot_id": "A0AC58HNI9_DANRE", "id": "A0AC58HNI9-1", "name": "[histone H3]-lysine(4) N-trimethyltransferase", "aln": "---------MMEAVIMERFISEGKGNGLR-ALREIKPGEVIYSCKPFAFCVARDFLKTACQSCLKRGESLSRCSQCKTARYCSVQCQKQAWPDHKRECKCLKHLQPR-IPTDSVRLVARIIFKLLS----QSE-SDQEELYSIAEHQSHLADMSEE--KKEGLKHLCTTLQVYLAEENCDLSRLPSGLDPVSLLARVTCNCFSISDGE-LQDVGVGLYPRNMFSTIMLQDRAECVSLSPGRGWLCLTAQILHTSTGINRKLLENKSYAGVTMHGMSLLNHDCQPNCIMMFEG-------------KRLTLRAVRVIRSA--EELTISYTDILAPSKDRRSQLQEQYHFRCECKRCSTEDKDCEMLSGE-------------------------KSAWTSIKDSIHHLEQLQSEQHWDELLKESQALLHRHSDVVPDRNIYMLRLLDLAMDACISLDDYETALEYGNRALGPYKLYFSDPHPSRAVELLRVGKLQHFLGRLEEARGSFTQAYSIMSVTHGAAHALTNQVQRRLSECQAELNTL---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4X8-1", "uniprot_id": "Q9W4X8_DROME", "id": "Q9W4X8-1", "name": "", "aln": "MATATVGSSRSATTSATASACSSKSKNLKNPAPQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEAT-KVLKCSNCRYVSYCHRSCQMQAWGQHKHECPFLKKVHPR-VVPDAARMLCRLILRLEHGGDLIRGYYTEHGSRKFRDLMSHYAEIKNDPMRLEHLDSLHAVLTDMMAESPSTVPNKT---ELMSIYGRLITNGFNILDAE-MNSIATAIYLG------------------------------------------------------VSITDHSCQPNAVATFEG-------------NELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKCTDAKESKEMLAALCPNRNCGAGISVDRNNCPRCDAGISPKLRNAFNEAMTLTRHNLENMKDVAYLDVCKVCLDKQTGVFHPLNVWYVKTLDAAFEAAIEVGKWSDALDYGQRLLPGFRKYHGPWNPLLGLLHMKLGKIQLYEGHSKEALHHLEEAQRILTVTHGRDHRLLTEQLYMLVLQARQEAH----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...*: .: : . : : *. *: :*..*: . ** ** * *: ** : : *: *:: : . . : : : . : . : * *.: : . :. :. .:: : : :*.* ** . ::*: : .:: .* *:* . :* *:. * * * * .* . . : : : .. . *: :: : . . * *. : : : . . :: * . : * *: :.** * : ", "identical_positions": 41, "similar_positions": 92, "identity": "7.06%" }, { "cls_id": "homologset.agr.FB:FBgn0011569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38129-1", "uniprot_id": "TAF5_YEAST", "id": "P38129-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF5", "aln": "-------------------MSQKQSTNQNQNGTHQPQPVKNQRTNNAAGANSGQQPQQQS-------------------QGQSQQQGRSNGPFSASDLNRIVLEYLNKKGYHRTEAMLRAESGRTLTPQNKQSPANTKTGKFPEQSSIPPNPG---------------KTAKPISNPTNLSSKRDAEGGIVSSGRLEGLN------APENYIRAYSMLKNWVDSSLEIYKP-------ELSYIMYPIFIYLFLNLVAKNPVYARRFFDRFSP-----------DFKDFHGSEINRLFSVNSIDHIKENEVASAFQSHKYRITMSKTTLNLLLYFLNENESIGGSLIISVINQHLDPNIVESVTAREKLADG---IKVLSDSENGNGKQNLEMNSVPVKLGPFPKDEEFVKEIETELKIKDDQEKQLNQQTAGDNYSGANNRTLL-----QEYKAMNNEKFKDNTGDDDKDKIKDKIAKDEEKKESELKVDGEKKDSNLSSP-ARDILPLPPK----TALDLKLEIQKVKESRDAIKLDNLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGS---------SLNNPNIALNNNDKDEDP-----TCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEPFIGYLGDVTASIN---------------------------------------------QDIKEYGRRRTVIPTSDLVASFYTKKTPVFKVKFSRSNLALAGGAFRP", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VT91-1", "uniprot_id": "Q9VT91_DROME", "id": "Q9VT91-1", "name": "", "aln": "MDLPLPILIPSSDEVYVISDSDDSDSDDIRNELMKLEDNKDKPKNKERQKSKNENSQIKMNKWYLKEFEDLMGLEIACSDDEDDIDDRNSEIWSSSESDKISDSDDSNSDGSPTEWINRIKN-VNLFPFN-KSAEDEKPKACEELPSIPVFTGPMPSMPIYDEETCQFEMVPPIIQPDLIKEVTDAEMPIELDKSDSELEKEKLKADEDDNFSDSNTSSSFSLSSLDDYDYGETDLDEQHNENKCTYWEEMSLRPVDKGEVSQEELMAILNEDESSPDHRSECDIDEAIRTRDGSDFYEDSAQFLENMENVSLLVIKEDSVFADYEFAVKKLIKLIQSTPSHYKYEIYILLYPLLVLTYLQMMASDKIQKARMLLVRFQDHLDDSYISRIIKLREISKPAEVPNKARKLLAGLEKVKIEMSEGAFRQLLLCTEEWTRGQQEKLLSHFQIQPYSEDDKPQQRFAIGQPLLEPIWYGAPEPLHKKDFAARPFFQKRRKKRSEPQLSDNLHLPPVNRVYNPIPNKMDLLHMK-SDEQYRMKLDRNNLPSTYLYTTSPSDEVVICATFSEGNSMLALGTVSSKVYVFSLKPSKLVQVKAAQWLKNLDTGMAGVDKDMIDPIKKFTRRTLYGHQGPVYGCSFNPEDRFLITCSEDFSVRLWCLLSWSCVVIFSGHLAPVCFVVFAPRGYYFATASDDCTARVWMQDNTKPARILQGHLAELGVCLFHPNRHYMATGSADCTVRIWDIVKAVQVRIFRGHKSRITALIYSICGRYLVSGGDDNLIMIWDTAN-EILMQFFDHHKASINTMEISLDNNILVVGGQDCQLTLWDFEQVIKNYLNRAKISMKNQAGTQESSANNLLVSSFFTKGEPFYMIRFTRRNLLLGFCVTPREFENDVLDVKLNQNKHKEEKKKELGEWLDFLDTIKLKACYDLKDEINLDTSQVEKENKS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:...::: :* : : *:: .*: ...::.* : :.:.: :.*.. :*:*: ::* . .:.. ** : * :. .* * * :*. : *. * .*** .* : . ** :* :.. *** * . . *: :: : . ..: ***: *. : . . : : *. * *. * ..:: :. *:.: :. . * :* :.::: * .* : :: : . * * :. . . * :: * .: * :*: .. : :.* :.. ..: * . .*:. . : ::**: .: : . :::: .::..** * *. :: : : *: : * .: .**: : :*: .: *.* * * *** ..: *::: ::* * : ::. : ***. :** . ::: : * **:. : * * .* : ::**. * *:* : .: . *** * :** **.*.**. **.*::::*:: *** :****.: : :.:* :.** ** * *:* *:******.* ***:* *: * **: *** ::. **** *: ***:* * *:**: .. .**:* **.: : :: . **:* :*.:*.:* :** .. : * *: .* * :* ::. * :.*:*: ** * : :**:::. .: ... .: . * :* * *: :: ::: : *:: :: * :* ::. .. : ", "identical_positions": 184, "similar_positions": 288, "identity": "19.43%" }, { "cls_id": "homologset.agr.FB:FBgn0011570", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI32-1", "uniprot_id": "CAPZB_RAT", "id": "Q5XI32-1", "name": "F-actin-capping protein subunit beta", "aln": "MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYDPPLE-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTNKSG-SGTMNLGGSLTRQMEKDETVSDC-------SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47756-2", "uniprot_id": "CAPZB_HUMAN", "id": "P47756-2", "name": "F-actin-capping protein subunit beta", "aln": "MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYDPPLE-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTNKSG-SGTMNLGGSLTRQMEKDETVSDC-------SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUB3-1", "uniprot_id": "A0A8M3AUB3_DANRE", "id": "A0A8M3AUB3-1", "name": "F-actin-capping protein subunit beta", "aln": "MNEQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYEPPID-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTTKTG-SGTMNLGGSLTRQMEKDETVSES-------SPHIANIGRLVEEMENKIRSTLNEIYFGKTKDIVNGLRSIESLPDNQKYRQLQRELSQVLTQRQIYID---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47757-1", "uniprot_id": "CAPZB_MOUSE", "id": "P47757-1", "name": "F-actin-capping protein subunit beta", "aln": "MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKV-VGKDYLLCDYNRDGDSYRSPWSNKYDPPLE-----DGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLD------HGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEK-SSGRTAHYKLTSTVMLWLQTNKSG-SGTMNLGGSLTRQMEKDETVSDC-------SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQRQVYIQPDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48603-1", "uniprot_id": "CAPZB_DROME", "id": "P48603-1", "name": "F-actin-capping protein subunit beta", "aln": "MSEMQMDCALDLMRRLPPQQIEKNLIDLIDLAPDLCEDLLSSVDQPLKIAKDKE-HGKDYLLCDYNRDGDSYRSPWSNSYYPPLE-----DGQMPSERLRKLEIEANYAFDQYREMYYEGGVSSVYLWDLD------HGFAAVILIKKAGDGSKMIRGCWDSIHVVEVQEK-TTGRTAHYKLTSTAMLWLQTNKQG-SGTMNLGGSLTRQQEQDANVSES-------SPHIANIGKMVEEMENKIRNTLNEIYFGKTKDIVNGLRSTQSLADQRQQAAMKQDLAAAILRRNVKPESN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13517-1", "uniprot_id": "CAPZB_YEAST", "id": "P13517-1", "name": "F-actin-capping protein subunit beta", "aln": "MSDAQFDAALDLLRRLNPTTLQENLNNLIELQPNLAQDLLSSVDVPLSTQKDSADSNREYLCCDYNRDIDSFRSPWSNTYYPELSPKDLQDSPFPSAPLRKLEILANDSFDVYRDLYYEGGISSVYLWDLNEEDFNGHDFAGVVLFKKNQSD----HSNWDSIHVFEVTTSPSSPDSFNYRVTTTIILHLDKTKTDQNSHMMLSGNLTRQTEKDIAIDMSRPLDVIFTSHVANLGSLIEDIESQMRNLLETVYFEKTRDIFH--QTKNAAIASSAEEANKDAQAEVIRGLQSL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *:*.****:*** * :::** :**:* *.*.:******* **. :*. .::** ****** **:******.* * :. *. :** *****: ** :** **::*:***:********: *.**.*:*:** .. :. ******.** . :: : :*::*:* :* *:..* . .. * *.*.**** *:* :. . :.*:**:* ::*::*.::*. *: :** **:**.: :: :: . : .: : ", "identical_positions": 116, "similar_positions": 88, "identity": "38.93%" }, { "cls_id": "homologset.agr.FB:FBgn0011573", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63692-1", "uniprot_id": "CDC37_RAT", "id": "Q63692-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSVWDHIEVSDD-EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV-AEGGGQVELERLRAEAQQLRK----------------EERSWEQKLEDMRKKEKNMPW------------------------NVDTLSKD------------GFSKSMVNTK---------------PEKAEED--SEEAREQKHKTFVEKYE------KQIKHFG--MLHRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKV------DPRACFRQFFTKIKTAD------QQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG----------------GLDPVEVYES-LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKSGEAK----EGEEAGPGDPLLEAVPKAGNEKDISA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61081-1", "uniprot_id": "CDC37_MOUSE", "id": "Q61081-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSVWDHIEVSDD-EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV-AESDGQVELERLRAEAQQLRK----------------EERSWEQKLEDMRKKEKNMPW------------------------NVDTLSKD------------GFSKSMVNTK---------------PEKAEED--SEEAREQKHKTFVEKYE------KQIKHFG--MLHRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKV------DPRACFRQFFTKIKTAD------HQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG----------------GLDPVEVYES-LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKSGEAK----EGEEAGPGDPLLEAVPKAGNEKDVSA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16543-1", "uniprot_id": "CDC37_HUMAN", "id": "Q16543-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSVWDHIEVSDD-EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV-AEG-GKAELERLQAEAQQLRK----------------EERSWEQKLEEMRKKEKSMPW------------------------NVDTLSKD------------GFSKSMVNTK---------------PEKTEED--SEEVREQKHKTFVEKYE------KQIKHFG--MLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKV------DPRACFRQFFTKIKTAD------RQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG----------------GLDPVEVYES-LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAK----EGEEAGPGDPLLEAVPKTGDEKDVSV----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24276-1", "uniprot_id": "CDC37_DROME", "id": "Q24276-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "----------MVDYSKWKNIEISDD-EDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSYQARLMDVKERISKKDG-DEEALKKELEKIEAEGKELDR----------------IES-------EMIKKEKKTPW------------------------NVDTISKP------------GFEKTVINKK---------------AGRKPDENLSEEEREQRMKQFVKENE------KLCQQYG--MLRKYDDSKRFLQEHLHLVGEETANYLVIWSINLEMEEKHELMAHVAHQCICMQYILELAKQLDV------DPRACVSSFFSKIQHCH------PEYRAQFDSEIEGFKGRIQKRAQEKIQEAIAQAEEEERKERLGPG----------------GLDPADVFES-LPDELKACFESRDVELLQKTIAAMPVDVAKLHMKRCVDSGLWVPNAADLEGD----KKEEDDSDD-VAGGEEKTDDAKSESAAKEEPIYTGVSTEDVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9CZP7-1", "uniprot_id": "CD37L_MOUSE", "id": "Q9CZP7-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSFPRTGGETEEESD-LDVSPSSSHYSPVPDGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQ----------------REEEWRQKEEALVQRERMCLW------------------------NMDAISKD------------VFNKSFINQ-----------------DKRK------TEEEDKSQSFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPHLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKSRVRLYAQS---QSLQPVTVQN---HVPHS----------------GVGCIGSLES-LPQNPD-------------------------SLQCCTPAPLCSVDSVVHK--------EDDD-RMMDTV-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XIC3-1", "uniprot_id": "CD37L_RAT", "id": "Q5XIC3-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSFPRTGGETEEESD-LDVSPSSSHYSPVPDGGAQMYSHGIELACQRQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQ----------------REEEWRQKEEALVQRERTCLW------------------------NVDAISKD------------VFNKSFINQ-----------------DKRK------TEDEDKSQSFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKARVRLYAQS---QSFAPVTVEN---HAPHS----------------GVGCIGSAEP-LPQNPD-------------------------SLQCCPPAPLCSVDSVVHK--------EDDD-RMMDTV-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L3B6-1", "uniprot_id": "CD37L_HUMAN", "id": "Q7L3B6-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "MEQPWPPPGPWSLPRAEGEAEEESD-FDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQ----------------REEEWRQKEEALVQREKMCLW------------------------STDAISKD------------VFNKSFINQ-----------------DKRKD-----TEDEDKSESFMQKYE------QKIRHFG--MLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNV------DPRGCFRLFFQKAKAEE------EGYFEAFKNELEAFKSRVRLYSQS---QSFQPMTVQN---HVPHS----------------GVGSIGLLES-LPQNPD-------------------------YLQYSISTALCSLNSVVHK--------EDDEPKMMDTV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7YY97-1", "uniprot_id": "CD37L_DANRE", "id": "A7YY97-1", "name": "Hsp90 co-chaperone Cdc37-like 1", "aln": "--------------------------------------------------MASLCQRQQHCVKASIASEWQLAEAQDQLCGLELHSSESVEQERARALASSTELSH----------------TEHQWRLKERMLG---TLCP----------------------------EANRD------------VFDKSIINI-----------------TQSWPN----ESDPDKSLNFVQRNE------ELLKHFG--MLGRWDDSQRFLAEYHHLICEETANYLILWCFRLQAEKKEALMEQVAHQAVVMQFILEMARNTQQ------DPRGCFRHFFQKAKAGQ------EGYLDVFHTELQAFKDRVKEYTMKSTGETPKDTVHQN---TPPAC----------------CLDPKEVFES-LPQELKTCIQMQDMQILQNVLSSMNPQVAEYHVKRCLEAGLWTNIPRTSKDE----SSEVDEWKMMET------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06101-1", "uniprot_id": "CDC37_YEAST", "id": "P06101-1", "name": "Hsp90 co-chaperone Cdc37", "aln": "---------MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYSHLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQLAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKLDELYKEKNAHISSEDIHTGFDSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTELEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKLLEVFNDIDIIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVKHTADTVD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . : : :: : * : : *..:.:* . *:. : : ..:* : .:..*:::* : :: *: . *:: .: : . . : :: ** * :* *: . : . ** * . : .. :: :: * : :: : :. :*:: . :: : . : : ", "identical_positions": 19, "similar_positions": 77, "identity": "3.68%" }, { "cls_id": "homologset.agr.FB:FBgn0011576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RRT9-1", "uniprot_id": "CP4V2_RAT", "id": "A2RRT9-1", "name": "Cytochrome P450 4V2", "aln": "---------------MLWLWLGLSGQKLLLWGAASAVSVAGATVLLNILQMLVSYARKWQQMR-PIPSVARAYPLVGHALFMKPNNTEFFQQIIQYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFMYKFLQPWLGLG---LLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNKLEKHVN---QEAFNCFFPITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFK--EGRDHKKGLKSLHTFTNNVIAER-VNARKAEQDCIGAGRGPLPSKTKRKAFLDLLLSVTDEEGNK----LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHR-PVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAG-YKISKGTEAVIIPYALHRDPRYFPDPEEFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWIESNQKR--EELGLAGDLILRPN-NGIWIKLKRRHEDDP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBW0-1", "uniprot_id": "CP4V2_MOUSE", "id": "Q9DBW0-1", "name": "Cytochrome P450 4V2", "aln": "---------------MLWLWLGLSGQKLLLWGAASAVSLAGATILISIFPMLVSYARKWQQMR-SIPSVARAYPLVGHALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLG---LLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVN---QEAFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFK--EGRDHKRGLKCLHTFTNNVIAER-VKERKAEEDWTGAGRGPIPSKNKRKAFLDLLLSVTDEEGNR----LSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHR-PVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGG-YKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKR--EELGLAGDLILRPN-NGIWIKLKRRHEDDP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWL3-1", "uniprot_id": "CP4V2_HUMAN", "id": "Q6ZWL3-1", "name": "Cytochrome P450 4V2", "aln": "---------------MAGLWLGLVWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMR-PIPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLG---LLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHIN---QEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFK--EGWEHKKSLQILHTFTNSVIAER-ANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNR----LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDR-PATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG-YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKR--EELGLEGQLILRPS-NGIWIKLKRRNADER----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27589-1", "uniprot_id": "CP4D2_DROME", "id": "Q27589-1", "name": "Cytochrome P450 4d2", "aln": "-----------------------------------MLGVVGVLLLVAFATLLLWDFLWRRRGN-GILPGPRPLPFLGNLLMYRGLDPEQIMDFVK-KNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDG---LLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADG--MTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQST-IDGAP----LSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRG-KHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQ-IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPE--PRHSMN--IVLRSA-NGVHLGLKPRA--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22443-1", "uniprot_id": "CP19A_RAT", "id": "P22443-1", "name": "Aromatase", "aln": "---------------MFLEMLNPMHYNVTIMVPETVPVSAMPLLLIMGLLLLIRNCESSSSIP-GPGYCLGIGPLISHGRFLWMG-----IGSACNYYNKMYGEFMRVWISGEETLIISKSSSMVHVMKHSNYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTVRPFFMKALTGPGLIRMVEVCVESIKQHLDRLGDVTDN--SGYVDVVTLMRHIMLDTSNTLFLGIPLDESS-----IVKKIQGYFNAWQALLIKPNIFFKISWLYRK------YERSVKDLKDEIEILVEKK---------------RQKVSSAEKLEDCMDFATDLIFAERRGD---LTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHTVVG--DR-DIRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDVIDG-YPVKKGTNIILNIGRMHR-LEYFPKPNEFTLENFEKNVPY----RYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVKTLQKRCIENMPKNNDLSLHLDEDSPIVEIIFRHIFNTPFLQCLYISL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54781-1", "uniprot_id": "ERG5_YEAST", "id": "P54781-1", "name": "C-22 sterol desaturase ERG5", "aln": "MSSVAENIIQHATHNSTLHQLAKDQPSVGVTTAFSILDTLKSMSYLKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFLESLDPKFEEYKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCN---WVFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILCALSLNSFCGNYITEDQ------VRKIADDYYLVTAALELVNFPIIIPYTKTWY----GKKTADMAMKIFENCAQMAK---------DHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLSEKIKVFATIFPKDD---LLLTFKKRDPITGEVFE------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . : : : : : :: .: : :: . * : : * : : :.:: . . : * : .. *: : : . : . . :: : : :. . : ::.::: : : ::: . *: : : :. *:* : .* * . : : ::: : .*:*:** * * :. :: : *: : . : .*:** *.: : *. **: * *: .:: : : . . : : : : * ", "identical_positions": 27, "similar_positions": 103, "identity": "4.75%" }, { "cls_id": "homologset.agr.FB:FBgn0011582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18901-1", "uniprot_id": "DRD1_RAT", "id": "P18901-1", "name": "D(1A) dopamine receptor", "aln": "-------------------------------------------------------------------------------------------------------MAPNTSTMDEAGLPAERDFS------------------FRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLG-PFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFT-------------SLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN-----CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCG-----SEETQPFCIDSITFDVFVWFGWANSSLNPIIY-AFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSE-------------DLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61616-1", "uniprot_id": "DRD1_MOUSE", "id": "Q61616-1", "name": "D(1A) dopamine receptor", "aln": "-------------------------------------------------------------------------------------------------------MAPNTSTMDETGLPVERDFS------------------FRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFG-SFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFT-------------SLEDAEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN-----CQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCG-----SEETQPFCIDSITFDVFVWFGWANSSLNPIIY-AFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSE-------------DLKREEAGGIPKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21728-1", "uniprot_id": "DRD1_HUMAN", "id": "P21728-1", "name": "D(1A) dopamine receptor", "aln": "------------------------------------------------------------------------------------------------------MRTLNTSAMDGTGLVVERDFS------------------VRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFG-SFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNAT-------------SLAETID-NCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN-----CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCG-----SGETQPFCIDSNTFDVFVWFGWANSSLNPIIY-AFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSE-------------DLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F359-1", "uniprot_id": "E7F359_DANRE", "id": "E7F359-1", "name": "Dopamine D1 receptor", "aln": "----------------------------------------------------------------------------------------------------MAVKDLNVTTVIDSGF-MESDQS------------------TRVLTGCFLSLLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAILVMPWKAVTEVAGFWPFG-AFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISVAWTLSVLISFIPVQLKWHKAQPTSFPEANAS-------------HRALLTD-NCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAKI-----RHDSMGSSSNVDS---ESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCK-----RTSVGLPCISPTTFDVFVWFGWANSSLNPIIY-AFNADFRRAFAILLGCQRLCPGSN-SMETPSLNKN----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25115-1", "uniprot_id": "DRD5_RAT", "id": "P25115-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLPPGRNRTAQPARLGLQRQLAQVDAPAGSA----TPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFG-TFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGL---LSNGTPWEEG-WELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQS-----CRS-RGAYE------PDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIY-AFNADFRKVFAQLLGCSHFCFRTP--VQTVNISN---ELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEE---EEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLD9-1", "uniprot_id": "DRD5_MOUSE", "id": "Q8BLD9-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLPPGRNGTAHRARLGLQRQLAQVDAPGGSA----APLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFG-AFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVALAWTLSILISFIPVQLNWHRDKAGSQGREGL---LSNETPWEEG-WELDGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQS-----CRS-RGACE------PDPSLRASIKKETKVFKTLSVIMGVFVCCWLPFFILNCMVPFCSSGDAQGPRTGFPCVSETTFDIFVWFGWANSSLNPIIY-AFNADFRKVFAQLLGCSHLCFRTP--VQTVNISN---ELISYNQDTVFHREIAAAYVHMIPNAVSSGDREVGEEEEAEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFHKTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21918-1", "uniprot_id": "DRD5_HUMAN", "id": "P21918-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGA--PPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQS-----CRS-SAACA------PDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCS-GHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIY-AFNADFQKVFAQLLGCSHFCSRTP--VETVNISN---ELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDE---EEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RJ11-1", "uniprot_id": "A0A8M1RJ11_DANRE", "id": "A0A8M1RJ11-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLNGTVTGTEPREML-------------------------ARALTGCLLCALILWTLFGNILVCAAVLRFRHLRTKVTNIFIVSLAVSDLFVAVLVMPWKAVSEVAGFWPFG-AFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMIGAAWTLSVLISFIPVQLDWHKAAARSGG---------------------GGNAGDCDSSLNREYAISSSLISFYIPVAIMIVTYTRIYRIAQIQIRRIASLERAAEHAQS-----CRSNRLACQ------HHSSLKSSISRETKVLKTLSVIMGVFVCCWLPFFVLNCVVPFCH----DKPSAGLPCVSDTTFDVFVWFGWTNSSLNPVIY-AFNAEFRKGFSSLLGCRGRC-RTP--VETVNISN---ELVSYNQDTLLHKEIVSAYVNIIPNVVDD---------------TFDRISQLSRE--DEDACTDSVCELECDAEP----RAPFTANGIH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41596-1", "uniprot_id": "DOPR1_DROME", "id": "P41596-1", "name": "Dopamine receptor 1", "aln": "MYTPHPFGFLIILVPMTNAMRAIAAIAAGVGSVAATVATSTTSSISSSTTIINTSSATTIGGNHTSGSTGFSTNSTLLDADHLPLQLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNESSWTNASEMDTIVGEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLR-RIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGK------------------KYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCK-----------TCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMRNPWCCAQ------DVGN-----IHPRNSDRFITDYAAKNVVVMN-------------------------------------SGRSSAELEQVSAI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. :* **. :: ** *** *: * ** .: *.*: ***::**:** ***.: .* :: *:* :* **: *****:*********** **:*** *. *::* * :* : *.: :. * *: ::**:*:.* *: * *. **: ** ****:* .:** * :* ** ::: * :: *.. *: : .. : *. *:.:*****: **:*** * .** *:. **.::.*:*::**::**:** ** :*: * :* : .:.: ", "identical_positions": 115, "similar_positions": 87, "identity": "18.98%" }, { "cls_id": "homologset.agr.FB:FBgn0011584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BU14-1", "uniprot_id": "SEC62_MOUSE", "id": "Q8BU14-1", "name": "Translocation protein SEC62", "aln": "--------MAERRRHKKR-------------IQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVECLLDSKWAKAKKGEDALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDVKKEKDKGKSESGKEDDKKSKKESVKEEKTKKEKEKKKDGEKEDSKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVFVWIYDPVHIKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAIARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKG----PKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKGAPADHGPEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCDE-EDDDKDGEVPKSAHEKS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99442-1", "uniprot_id": "SEC62_HUMAN", "id": "Q99442-1", "name": "Translocation protein SEC62", "aln": "--------MAERRRHKKR-------------IQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSKWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKG----PKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL49-1", "uniprot_id": "Q9VL49_DROME", "id": "Q9VL49-1", "name": "Translocation protein SEC62", "aln": "MSGEEEYFQEEEEEEQEQDIYDDGTEYTEPGAQKVDKPSKDEKNVAKWLKKNVKTKKTKFLSHIVEYFTSSKAIDALLKSKFTEG---SNPLFTTREQVIEFLDVMLEHKFFHRAKKVPVTLEEIRGKSGGDKKADKEKTQDKEKDKAKDEKKDTDPEGDNGQGDGGASGNEKEKE----KKEKKKRKIRLDMHPEQIFVDGSEAYVWIYDPIPLHYWIFGFILLLGAVGICLFPLWPPLLRKGVYYLSIAAAGFLVFILALTIVRLIVFIIVWALTGGKLHFWIFPNLTEDVSFFASFWPLYESNYNSDPNNSSAKTDKKSKSKDKKKEKESDAEDTAVDADGDADGDVDAEVSTLEPEKIELIKEHDTDMEIRKRRKVGADDYEEDDVDEEETKAQPKDSKAGTPRNSGSDSESSSKDYEIISSSEVQNVAGN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21825-1", "uniprot_id": "SEC62_YEAST", "id": "P21825-1", "name": "Translocation protein SEC62", "aln": "--------MSAVGPGSNAG-------------ASVNGGSATAIATLLRNHKELKQRQGLFQAKQTDFFRYKRFVRALHSEEYANKSARQPEIYPT-IPSNKIEDQLKSREIFIQLIKAQMVIPVKKLHSQECKEHG----------------------------------------------LKPSKDFPHLIVSNKAQLEADEYFVWNYNPRTYMDYLIVIGVVSIILALVCYPLWPRSMRRGSYYVSLGAFGILAGFFAVAILRLILYVLSLIVYKDVGGFWIFPNLFEDCGVLESFKPLYGFGEKD-----TYSYKKKLKRMKKKQAKRESNKKKAINEKAEQN----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .*. * . : : :. : .: .::* .: : .* ..:::: . ::.* . : : .:::* : *. :. * : .:.: :: ::..* :** *:* ::: : :: :. :**** :* * **:*:.* ::. :: ::: * *:::: : . **::*** * ..: ** *** :. . . .*. * **: * .. :.. : . : : ", "identical_positions": 41, "similar_positions": 101, "identity": "9.43%" }, { "cls_id": "homologset.agr.FB:FBgn0011586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q98874-1", "uniprot_id": "ERH_DANRE", "id": "Q98874-1", "name": "Enhancer of rudimentary homolog", "aln": "---------------------------------MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFVDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6GLN9-1", "uniprot_id": "A0A8I6GLN9_RAT", "id": "A0A8I6GLN9-1", "name": "Enhancer of rudimentary homolog", "aln": "--------------CCAQVREDIRIFIEVVFPLQSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84089-1", "uniprot_id": "ERH_MOUSE", "id": "P84089-1", "name": "Enhancer of rudimentary homolog", "aln": "---------------------------------MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84090-1", "uniprot_id": "ERH_HUMAN", "id": "P84090-1", "name": "Enhancer of rudimentary homolog", "aln": "---------------------------------MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24337-1", "uniprot_id": "ER_DROME", "id": "Q24337-1", "name": "Protein enhancer of rudimentary", "aln": "---------------------------------MSHTILLVQPGARPETRTYCDYESVNECMEGVCKIYEEHLKRRNPNTPTITYDISQLFDFIDTMVDISCMVYQKSTNTYAPYNKDWIKEKIYVLLRQAAFSSNT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4A5C2-1", "uniprot_id": "D4A5C2_RAT", "id": "D4A5C2-1", "name": "Enhancer of rudimentary homolog", "aln": "MLHQLSRDLLLEALLLSACVVWFRLDCRLAFAAMTPIKLLVQPTQRPEGRTYAEYGSVNECMEGICKMYEEHLKRLNPLSQSITYGVSQLFEFIDRMVDLSCLVFREDTQTYKPHSREWVKERIYMLLSQQAQRDESE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***** *** ***.:* ********:**:******* ** : :***.:****:*:* :.*:**:*:: .*:** *:.::*:**:**:** : * . ", "identical_positions": 56, "similar_positions": 28, "identity": "40.58%" }, { "cls_id": "homologset.agr.FB:FBgn0011589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89047-1", "uniprot_id": "KCNH3_RAT", "id": "O89047-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH3", "aln": "MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEVMQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEKGEVALFLVSHKDISET----------------------------------------KNRGGPDNWKERGGGRRRYGRAGSKGFNANRRRSRAVLYHLSGHLQ--KQPK-GKHKLNKGVFGEKPN-LPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICLHYVTTWFLLDVIAALPFDLLHAFKVN--VYVGAHLLKTVRLLRLLRLLPRLDRYSQYSAVVLTLLMAVFALLAHWVACVWFYIGQQEIENSESELPEIGWLQELARRLETPYYLVSRSPDGGNSSGQSENCSSS--------GGGSEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPQREQ------------------VVKANADVKGLTYCVLQCLQLAGLHESLALYPEFAPRFSRGLRGELSYNLGAGGVSAEVDTSSLSGDNTLMSTLEEKE-----------------TDGEQGHTISPAPADEPSSPLLSPGCTSSSS--------------------------------------AAKLLSPRRTAPRPRLGGRGRPSRAGVLKPEAGPSAHPRTLDG--LQLPPMPWNV----PPDLSPRVVDGIEDGCG-----------------------SDQ-HKFSFRVGQSGPECSSSPSPGTESGLLTVPLVPSEARNTDT------LDKLRQAVTELSEQVLQMREGLQSLRQAVQLILVPQGEGQ-----CPRVSGEGPCPATASGLLQPLRVDTGASSYCLQPPAGS--------VLSGTWPHPRPGHPPPLMAPWPWGP---------------------PASQSSPWPRATALWTSTSDSE-----PPGSGDLCSEPSTPASPPPPEEGARTGTPAPVSQAEATSTGEPPPGSGGRALPWDPHSLEMVLIGCHGPGSVQWTQEEGTGV----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVJ0-1", "uniprot_id": "KCNH3_MOUSE", "id": "Q9WVJ0-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH3", "aln": "MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEVMQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEKGEVALFLVSHKDISET----------------------------------------KNRGGPDNWKERGGGRRRYGRAGSKGFNANRRRSRAVLYHLSGHLQ--KQPK-GKHKLNKGVFGEKPN-LPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICLHYVTTWFLLDVIAALPFDLLHAFKVN--VYVGAHLLKTVRLLRLLRLLPRLDRYSQYSAVVLTLLMAVFALLAHWVACVWFYIGQQEIESSESELPEIGWLQELARRLETPYYLVSRSPDGGNSSGQSENCSSSSSSSGSGGGRGSEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPQREQ------------------VVKANADVKGLTYCVLQCLQLAGLHESLALYPEFAPRFSRGLRGELSYNLGAGGVSAEVDTSSLSGDNTLMSTLEEKE-----------------TDGEQGHTVSPAPADEPSSPLLSPGCTSSSS--------------------------------------AAKLLSPRRTAPRPRLGGRGRPSRAGVLKPEAGPSAHPRSLDG--LQLPPMPWNV----PPDLSPRVVDGIEDGCS-----------------------SDQ-PKFSFRVGQSGPECSSSPSPGTESGLLTVPLGPSEARNTDT------LDKLRQAVMELSEQVLQMREGLQSLRQAVQLILVPQGEGQ-----CPRGSGEEPCPATASGLLQPLRVDTGASSYCLQPPAGS--------VLSGTWPHPRPGQPPPLMAPWPWGP---------------------PASQSSPWPRATALWTSTSDSE-----PPGSGDLCSEPSTPASPPPSEEGARTGTPAPVSQAEATSTGEPPPGPGGRALPWDPHSLEMVLIGCHGPGTVQWTQEEGTGV----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULD8-1", "uniprot_id": "KCNH3_HUMAN", "id": "Q9ULD8-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH3", "aln": "MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEVMQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEKGEVALFLVSHKDISET----------------------------------------KNRGGPDRWKETGGGRRRYGRARSKGFNANRRRSRAVLYHLSGHLQ--KQPK-GKHKLNKGVFGEKPN-LPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICLHYVTTWFLLDVIAALPFDLLHAFKVN--VYFGAHLLKTVRLLRLLRLLPRLDRYSQYSAVVLTLLMAVFALLAHWVACVWFYIGQREIESSESELPEIGWLQELARRLETPYYLVGRRPAGGNSSGQSDNCSSS-----------SEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPRREQ------------------VVKANADVKGLTYCVLQCLQLAGLHDSLALYPEFAPRFSRGLRGELSYNLGAGGGSAEVDTSSLSGDNTLMSTLEEKE-----------------TDGEQGPTVSPAPADEPSSPLLSPGCTSSSS--------------------------------------AAKLLSPRRTAPRPRLGGRGRPGRAGALKAEAGPSAPPRALEG--LRLPPMPWNV----PPDLSPRVVDGIEDGCG-----------------------SDQ-PKFSFRVGQSGPECSSSPSPGPESGLLTVPHGPSEARNTDT------LDKLRQAVTELSEQVLQMREGLQSLRQAVQLVLAPHREGP-----CPRASGEGPCPASTSGLLQPLCVDTGASSYCLQPPAGS--------VLSGTWPHPRPG-PPPLMAPWPWGP---------------------PASQSSPWPRATAFWTSTSDSE-----PPASGDLCSEPSTPASPPPSEEGARTGPAEPVSQAEATSTGEPPPGSGGLALPWDPHSLEMVLIGCHGSGTVQWTQEEGTGV----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1T9-1", "uniprot_id": "KCNH4_RAT", "id": "Q9R1T9-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH4", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGPRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLQKALEGHQEHRAEICFYRKDGSAFWCLLDMMPIKNELGEVVLFLFSFKDISQSGGPGL---------------------------------GSPGIHGDNNNHENSLGRR---GASSR-LRSTRRQNRTVLHRLTGHFG--RRDQ-GSVKANSNVFEPKPS-VPEYKVASVGGSRCLLLHYSIPKAVWDGLILLATFYVAVTVPYNVCFAGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVVSAPRSIGLHYLATWFFVDLIAALPFDLLYVFNIT--VTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACVWYVIGRREMEANDPLLWDIGWLHELGKRLEEPYVN--------GSAG-------------------------------GPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEFLLRRGDALQAHYYVCSGSLEVLRDNTVLAILGKGDLIGADIPELGQEPGAG--------AG--CVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYVAAFRAGLPRDLTFNLRQG---SENNGLGRFSRSPRLSQARSDT-----------------LGSSSDKTLPSITETEGGMEPGAGSKPRRPLLLPN------------------LSPARPRGSLVSLLGEELPPFSALVSSPSLSPTPSPALAGRGSSPSLHGPPRGSAAWKPPQLLTPPLGTFG----PPDLSPRIVDGIEDSSN-----------------------TAEAPTFRFSKRPEPTRTRSQAPL-SGPRLSRELATEAAEEVKEK------VCRLNQEISRLNQEVSQLSRELRQVMGLLQARLGPPSHPP-----DSTWLPDLPCPHQ--------------RPPCISPHMSG---------------------PPPGLQNTTLAV----------------------VHCPAS-VGTVEIGATPSELR-----SSMVPPFPSEPDPLGPSPVPEASPLTPSLLKHSFQSGSDTFH--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A5F7-1", "uniprot_id": "A2A5F7_MOUSE", "id": "A2A5F7-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH4", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGPRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLQKALEGHQEHRTEICFYRKDGSAFWCLLDMMPIKNEMGEVVLFLFSFKDISQSGGPGL---------------------------------GSPGIHGDNN-HENSLGRR---GTSSR-LRSTKRQNRTVLHRLTGHFG--RRGQ-SSVKANSNLFEPKPS-VPEYKVASVGGSRCLLLHYSIPKAVWDGLILLATFYVAVTVPYNVCFAGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFVDLIAALPFDLLYVFNIT--VTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACVWYVIGRREMEANDPLLWDIGWLHELGKRLEEPYVN--------GSAG-------------------------------GPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRDNMVLAILGKGDLIGADIPELGQEPGSG--------AGPSCVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYAAAFRAGLPRDLTFNLRQG---SENNGLGRFSRSPRLSQARSDT-----------------LGSSSDKTLPSITETEGGTEPGAGSKPRRPHLLPN------------------LSPARPRGSLVSLLGEELPPFSALVSSPSLSPTPSPALAGRGQSPSPHGPPRGSAAWKPPQLLIPPLGTFG----PPDLSPRIVDGIEDSSN-----------------------TAEAPTFRFSKRPEPTRTRSQAPP-SGPRLSRELATEAAEEVKEK------VCRLNQEISRLNQEVSQLSRELRQVMGLLQARLGPPSHTA-----GPAWLPDLPCPHQ--------------RLPCISPHMSG---------------------PPPGLQNTTLAV----------------------VHCPAS-VGTVEIGATPSELR-----PSTIPPYPSEPDPLGPSPAPEAPPLTPSLLKHSFQSGSDTFH--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQ05-1", "uniprot_id": "KCNH4_HUMAN", "id": "Q9UQ05-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH4", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGTRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLHKALEGHQEHRAEICFYRKDGSAFWCLLDMMPIKNEMGEVVLFLFSFKDITQSGSPGL---------------------------------GPQGGRGDSN-HENSLGRR---GATWK-FRSARRRSRTVLHRLTGHFG--RRGQ-GGMKANNNVFEPKPS-VPEYKVASVGGSRCLLLHYSVSKAIWDGLILLATFYVAVTVPYNVCFSGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFIDLIAALPFDLLYIFNIT--VTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACIWYVIGRREMEANDPLLWDIGWLHELGKRLEVPYVN--------GSVG-------------------------------GPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRDNMVLAILGKGDLIGADIPEPGQEPGLG--------ADPNFVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYGAAFRAGLPRDLTFNLRQG---SDTSGLSRFSRSPRLSQPRSES-----------------LGSSSDKTLPSITEAESGAEPGGGPRPRRPLLLPN------------------LSPARPRGSLVSLLGEELPPFSALVSSPSLSPSLSPALAGQGHSASPHGPPRCSAAWKPPQLLIPPLGTFG----PPDLSPRIVDGIEDSGS-----------------------TAEAPSFRFSRRPELPRPRSQAPP-TGTRPSPELASEA-EEVKEK------VCRLNQEISRLNQEVSQLSRELRHIMGLLQARLGPPGHPA-----GSAWTPDPPCPQL--------------RPPCLSPCASR---------------------PPPSLQDTTLAE----------------------VHCPAS-VGTMETGTALLDLR-----PSILPPYPSEPDPLGPSPVPEASPPTPSLLRHSFQSRSDTFH--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QWS8-1", "uniprot_id": "KCNH8_RAT", "id": "Q9QWS8-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH8", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEVMQKSCSCKFLFGVETNEQLMLQIEKSLEEKVEFKGEIMFYKKNGAPFWCLLDIVPIKNEKGDVVLFLASFKDITDT---------------------------------------KVKITSEDKKEDRAKGRS---RAGSH-FDSARRRSRAVLYHISGHLQ--RREK-NKLKINNNVFVDKPA-FPEYKVSDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFIGNEDLST-TRSTTVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIHYVTTWFIIDLIAALPFDLLYAFNVT--VVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVLTLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYG-------NNTLG-------------------------------GPSIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSDITMHLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSMEVLKDSMVLAILGKGDLIGANLSIKDQ------------------VIKTNADVKALTYCDLQCIILKGLFEVLGLYPEYAHKFVEDIQHDLTYNLREG---HESDVISRLSNKSTVPQAEPKG-----------------NGS-IKKRLPSIVEDEEEEE-VEEEETTSLSPIYTRG--------------SSVSHSKKTGSSKSYLGLSLKQLTSGTV-PFHSPIRVSSANSPKTKQEADPPNHGTRKEKNLKVQLCSLGTAG----TPELSPRIVDGIEDGNS-----------------------SEETQTFDFGSEQIRPEPRISPSL-GESEIGAAFLFIKAEETKQQ------INKLNSEVTTLTQEVSQLGKDMRSIMQLLENILSPQQPSQ-----FCSLHPTSICPSRES---FQTRVSWSAHQPCLHLQANG-----AHLYHGNVTSDIWS-VDPSLVGSNPQRTEAHEQSPVDSELHHSPNLAYSPSHCQVIQEGHLQFLRCISPHS-----DTTLTPLQSISATLSSSVCSSSETSLHLVLPSRSEEGSITHGPVSSFSLENLPGSWDREGMMSASTEPLENFPVEVVTSTADVKDSKAINV-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59111-1", "uniprot_id": "KCNH8_MOUSE", "id": "P59111-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH8", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEVMQKSCSCKFLFGVETNEQLMLQIEKSLEEKVEFKGEIMFYKKNGAPFWCLLDIVPIKNEKGDVVLFLASFKDITDT---------------------------------------KVKITSEDKKEDRTKGRS---RAGSH-FDSARRRSRAVLYHISGHLQ--RREK-NKLKINNNVFVDKPA-FPEYKASDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFIGNEDLST-TRSTTVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIHYVTTWFIIDLIAALPFDLLYAFNVT--VVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVLTLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYG-------NNTLG-------------------------------GPSIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSDITMHLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSMEVLKDSMVLAILGKGDLIGANLSIKDQ------------------VIKTNADVKALTYCDLQCIILKGLFEVLGLYPEYAHKFVEDIQHDLTYNLREG---HESDVISRLSNKSTVSQAEPKG-----------------NGS-INKRLPSIVEDEEEEE-VEEEETTSLSPIYTRG--------------SSVSHSKKTGSNKTYLGLSLKQLASGTV-PFHSPIRVSSANSPKTKQEADPPNHGRKKEKNLKVQLSSLGSAG----TPELSPRIVDGIEDGNS-----------------------NEETQTFDFGSEQIRPEPRISPPL-AESEIGAAFLFIKAEETKQQ------INKLNSEVTTLTQEVSQLGRDMRSIMQLLENILSPQQPSQ-----FCSLHPTPMCPSRES---LQTRVSWSAHQPCLHLQAGG-----AHLYHGNVASGIWS-VDPSLVGSSPQRTEAHEQNPADSELHHSPNLDYSPSHCQVIQEGHLQFLRCISPHS-----DTTLTPLQSISATLSSSVCSSSETSLHLVLPSRSEEGSITHGPVSSFSLENLPGSWDREQMMSASSERLENFPVEVVTSTADVKDSKAINV-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L42-1", "uniprot_id": "KCNH8_HUMAN", "id": "Q96L42-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH8", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEVMQKSCSCKFLFGVETNEQLMLQIEKSLEEKTEFKGEIMFYKKNGSPFWCLLDIVPIKNEKGDVVLFLASFKDITDT---------------------------------------KVKITPEDKKEDKVKGRS---RAGTH-FDSARRRSRAVLYHISGHLQ--RREK-NKLKINNNVFVDKPA-FPEYKVSDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFIGNDDLST-TRSTTVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIHYVTTWFIIDLIAALPFDLLYAFNVT--VVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVLTLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYG-------NNTLG-------------------------------GPSIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSDITMHLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSMEVLKDSMVLAILGKGDLIGANLSIKDQ------------------VIKTNADVKALTYCDLQCIILKGLFEVLDLYPEYAHKFVEDIQHDLTYNLREG---HESDVISRLSNKSMVSQSEPKG-----------------NGN-INKRLPSIVEDEEEEEEGEEEEAVSLSPICTRG--------------SS-SRNKKVGSNKAYLGLSLKQLASGTV-PFHSPIRVSRSNSPKTKQEIDPPNHNKRKEKNLKLQLSTLNNAG----PPDLSPRIVDGIEDGNS-----------------------SEESQTFDFGSERIRSEPRISPPL-GDPEIGAAVLFIKAEETKQQ------INKLNSEVTTLTQEVSQLGKDMRNVIQLLENVLSPQQPSR-----FCSLHSTSVCPSRES---LQTRTSWSAHQPCLHLQTGGAAYTQAQLCSSNITSDIWS-VDPSSVGSSPQRTGAHEQNPADSELYHSPSLDYSPSHYQVVQEGHLQFLRCISPHS-----DSTLTPLQSISATLSSSVCSSSETSLHLVLPSRSEEGSFSQGTVSSFSLENLPGSWNQEGMASASTKPLENLPLEVVTSTAEVKDNKAINV-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I0J0-1", "uniprot_id": "A0AC58I0J0_DANRE", "id": "A0AC58I0J0-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH4", "aln": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVSKGFPIVYCSDGFCELTGFARTEVMQQSCACKFLYGPETSEHIILHVDAALEERSELKEEIMFYKKSGSVFWCLLDIVPIKNEKGDVVLFLASFKDVTDT---------------------------------------KAKSTLEEKKEECRREKV---KGDSP-FGSTRLRSSTVLYHISGHLH--NRQKQSKIKLNKNVFGDPPA-LPEYKVADAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFIGDQDL---TRSTTVTDIAVEILFIIDIVFSFRTTYVSKSGQVIFDARQICIHYMTTWFIIDLVAALPFDLLYAFKVS--VVSVVHLLKTVRLLRLLRLLQKMDRYSQHSTVVLTLLMSMFALLAHWMACIWYIIGKKEVESN-ADTWDIGWLHELGKRLESPYEGVA-----NRTLSS------------------------------GPSLRSIYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRWSSYHTRTKDLKDFIRVHHLPQSLKQRMLEYFQTTWSVNNGIDSNELLRDFPDELRSDIAMHLNKEILELSVFSSLSRGCLRSLSLHIKTSFCAPGEYLLRQGDALQALFFVCSGSMEVLKDNMVLAILGKGDLIGANMSVGDR------------------VIKTNADVKALTYCDLQCINLRGLYEVLDLYPEYSHRFVQDITHDLTYNLREG---QESHVISRMSSKSMDTQMEGRG-----------------NGD-AIQCYPPIAEHHNEEDDDDDDDEDDQ----------------------------------------IQYLSGG------------------GKQKTHMQKNDHQTNKKLHIQHTTVTKPD----LGNLSPRVVDGTEDSDG-----------------------TENSHTFIFSSAHQHSVSGATNTT-ATT----AELAAKSEDTRGQ------LRHLNQEVSSLGREVAELGRVMRSLAFLIESMMASPQTPG-----VYTSTFTSGHPS-----------------PPVPFQGQG-----SSWSSPNFPSPMHPGIHPGGLISLPLRPQELQ------------------VLCPTTSPGSFPIALSTTPHM-----DRFRQPLLTLSP--HSAVARTRSQSLETPHPQHHQHIPHAPGTLPRVGQPSL-GEGEDLRSLEESFWKCEKTAGKACNMIGDCGNYIPM---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZB14-1", "uniprot_id": "A1ZB14_DROME", "id": "A1ZB14-1", "name": "", "aln": "MPARKGLLAPQNTFLDTIATRFDGTHSNFVLGNAQAN-GNPIVYCSDGFVDLTGYSRAQIMQKGCSCHFLYGPDTKEEHKQQIEKSLSNKMELKLEVIFYKKEGAPFWCLFDIVPIKNEKRDVVLFLASHKDITHTKMLEMNVNEECDSVFALTAALLGARFRAGSNAGMLGLGGLPGLGGPAASDGDTEAGEGNNLDVPAGCNMGRRRSRAVLYQLSGHYKPEKGGVKTKLKLGNNFMHSTEAPFPEYKTQSIKKSRLILPHYGVFKGIWDWVILVATFYVALMVPYNAAFAK------ADRQTKVSDVIVEALFIVDILLNFRTTFVSRKGEVVSNSKQIAINYLRGWFALDLLAALPFDHLYASDLYDGEDSHIHLVKLTRLLRLARLLQKIDRYSQHTAMILTLLMFSFTLAAHWLACIWYVIAVK--EYEWFPESNIGWLQLLAERKNASVAI--------------------------------------------LTTAETYSTALYFTFTSLTSVGFGNVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDYFQTSWSLSHGIDIYETLREFPEELRGDVSMHLHREILQLPIFEAASQGCLKLLSLHIKTNFCAPGEYLIHKGDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQMTATTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDLTCNLREGYENQDSDIGPSFPLPSISEDDENREEAEEGGKGEKENGGGPPSGASPLHNISNSPLHATRSPLLGMGSPRNQRLHQRGRSLITLRETNKRHRTLNAACSLDRGSFEEPEPLEEEQSSGGKRPSLERLDSQVSTLHQDVAQLSAEVRNAISALQEMTFTSNAMTSHSSLKFPPARSIPNISGVAGTRSGVAVEHGLMGGVLAAAELAAMQRSSSHPPEVWGRDVQLPTSNTASSKAPSPVEPKKTMTSRSSQTDFYRIDFPTFERFVLANPRLVLGLLGIEPAIKNEMDLLQQKQTLQISPLNTIDECVSPSDHNLASSKERLITSSAVPTPGRIYPPLDDENSN----DFRWTMKHSASHHSCCKSTDALLSPEEQPPISILPVDATPAPSVQEVRSSKRSLRKSTSGSNSSLSSSSSSSNSCLVSQSTGNLTTTNASVHCSNSSQSVASVATTRRASWKLQHSRSGEYRRLSEATAEYSPPAKTPLPVAGVSYGGDEEESVELLGPRRNSRPILLGVSQNQGQGQAMNFRFSAGDADKLEKGLRGLPSTRSLRDPSSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. :************************:*.*** *:******* :*:*:.*:::**: *:* **:* :*.* :: :*. : * : *: :*:*.* ****:*::***** :*.*** *.**::.: . : :. :**::::** . * ....: .****. * :* * . :. ** .**:**:***: ***.... . * *: ** ***:**::.****:**:.*:*: .:.* ::*: ** :*::****** *: .: **:* .***** *** :::**** ::::***** *:* ***:**:*: *. * . ::***: *..* : . : . * ::***:::**********.*** :**:*:* *********:*************:* *.:: :**:*:: :*.:*: ****: :***::*::. *** * *:.:*:***.*::***::*:*:*.:* . *:***: *** ::. **:***:*:::****: :::*.**:**::.. *:********:*.:: *:::.:*:*.**** *: : ** : * ****: * .: :*: ** * : . . . . : . . .: * :.* . . . . : . . . . :: * : : :: :: . : . : : . ", "identical_positions": 291, "similar_positions": 231, "identity": "21.7%" }, { "cls_id": "homologset.agr.FB:FBgn0011591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1U9-1", "uniprot_id": "RFNG_RAT", "id": "Q9R1U9-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase radical fringe", "aln": "---------MSRVRRVLCRACLALAAVLAVLLLLPLP-LPLPLP------------------------LPRAPAPDPGRVPTGSLTLEVSRLQPD-----------------------------------------------------DVFIAVKTTRKNHGPRLRLLLRTWISRAPRQTFIFTDGDDPELQLLAGSQMINTNCSAVRTRQALCCKMSVEYDKFIESGRKWFCHVDDDNYVNPKSLLHLLSTFSSNQDIYLGRPSLDHPIEATERVQGGGTSNTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAERVRLPDDCTVGYIVEGLLGARLLHSPLFHSHLENLQKLPSGAVLQQVTLSYGGPENPHNVVNVAGSFSIRQDPTRFQSVHCLLYPDTHWCPMKNRGKEAFQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09009-1", "uniprot_id": "RFNG_MOUSE", "id": "O09009-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase radical fringe", "aln": "---------MSRARRVLCRACLALAAVLAVLLLLPLP-LPLPL--------------------------PRAPAPDPDRVPTRSLTLEGDRLQPD-----------------------------------------------------DVFIAVKTTRKNHGPRLRLLLRTWISRAPRQTFIFTDGDDPELQMLAGGRMINTNCSAVRTRQALCCKMSVEYDKFLESGRKWFCHVDDDNYVNPKSLLHLLSTFSSNQDIYLGRPSLDHPIEATERVQGGGTSNTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAERVRLPDDCTVGYIVEGLLGARLLHSPLFHSHLENLQRLPSGAILQQVTLSYGGPENPHNVVNVAGSFNIQQDPTRFQSVHCLLYPDTHWCPMKNRVEGAFQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y644-1", "uniprot_id": "RFNG_HUMAN", "id": "Q9Y644-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase radical fringe", "aln": "---------MSRARGALCRACLALAAALAALLLLPLP-LPRAPA------------------------PARTPAPAPRAPPSR---PAAPSLRPD-----------------------------------------------------DVFIAVKTTRKNHGPRLRLLLRTWISRARQQTFIFTDGDDPELELQGGDRVINTNCSAVRTRQALCCKMSVEYDKFIESGRKWFCHVDDDNYVNARSLLHLLSSFSPSQDVYLGRPSLDHPIEATERVQGGRTVTTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAEQVRLPDDCTVGYIVEGLLGARLLHSPLFHSHLENLQRLPPDTLLQQVTLSHGGPENPHNVVNVAGGFSLHQDPTRFKSIHCLLYPDTDWCPRQKQGAPTSR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6KFX9-1", "uniprot_id": "RFNG_DANRE", "id": "Q6KFX9-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase radical fringe", "aln": "---------MHLSHVASNKTCFLLSLAFCALLVLLIPSLQPPQR------------------------QADLPQPRPHAKPAKHP-LKNSLYRPNEDTR-------------------GGGFTQTPPPDNLEKMDDLNSHYRDFLDLRDIFIAVKTTRKYHKSRLQLLSQTWVSRAKEQTFIFTDGEDKELRLKAGLNIINTNCSAAHTRQALCCKMSVEYDKFIESQKKWFCHVDDDNYVILPSLLELLSSYSHTQDVYLGRPSLDHPIEAAERVKSDGSVS-VKFWFATGGAGFCISRGLALKMSPWASLGNFITTAEKIRLPDDCTIGYIIEALLEVPLTHTGLFHSHLENLQRLPAENILRQVTLSYGGFENRRNVVSVGGAFSLAEDPTRFKTVHCKLYPDTEWCPRKTRH----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V725-1", "uniprot_id": "G3V725_RAT", "id": "G3V725-1", "name": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "aln": "---------------MHCRVFRGLAGALFTLLCVGLLSLRYH--------------------------SSLSLRT------------MQGTLRLNQPN------------------------PGHLE-----------------LQLGDIFIGVKTTWAFHRSRLDLLLDTWVSRTRQQTFIFTDSPDELLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKALLQLLRTFPQDHDVYVGKPSLNRPIHASELQ-SKNRTRLVRFWFATGGAGFCINRQLALKMVPWASGSHFVDTSALIRLPDDCTVGYIIECKLGGHLQPSPLFHSHLETLQLLGTAQLLEQVTLSYGVFEGKLNIIKLPGPFSHEEDPSRFRSLHCLLYPDTPWCPLLAVP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09008-1", "uniprot_id": "MFNG_MOUSE", "id": "O09008-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "aln": "---------------MHCRLFRGMAGALFTLLCVGLLSLRYH--------------------------SSLSQRM------------IQGALRLNQRN------------------------PGPLE-----------------LQLGDIFIAVKTTWAFHRSRLDLLLDTWVSRIRQQTFIFTDSPDERLQERLGPHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKALLQLLKTFPQDRDVYVGKPSLNRPIHASELQ-SKNRTKLVRFWFATGGAGFCINRQLALKMVPWASGSHFVDTSALIRLPDDCTVGYIIECKLGGRLQPSPLFHSHLETLQLLGAAQLPEQVTLSYGVFEGKLNVIKLPGPFSHEEDPSRFRSLHCLLYPDTPWCPLLAAP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00587-1", "uniprot_id": "MFNG_HUMAN", "id": "O00587-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "aln": "---------------MQCRLPRGLAGALLTLLCMGLLCLRYH--------------------------LNLSPQR------------VQGTPELSQPN------------------------PGPPK-----------------LQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQ-PHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGAR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5YB40-1", "uniprot_id": "MFNG_DANRE", "id": "Q5YB40-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "aln": "--------------MILRRLFHVLPAFAFTLFILVLLDLQLR--------------------------TRSDQKPQNAHDGHQRTTFISETTAENQHR------------------------DGAHEKEKAEGQKWTEVRSTPPLELSDIFIAVKTTGRFHKSRLALLLETWISETKEHTYIFTDSPDADISS-EGFNVVVTNCSPEHSHQALSCKMAAEYDYFMASYKKWLCHVDDDNYLNPGALLSLLMAFPADGDIYVGKPSLDRPMRAQELL-EGNKTRDVHFWFATGGAGFCLSRNLAERMAPWASGPRFEQTSAVIMLPDDCTVGFIVERRLGISMIHSNMFHSHLENLLLLSPSDIPKQVTLSYGWFESKMNSVELKGVFTKDEDPSRFRTVHCLLYPTTSWCPVALKSALSWNQHVMH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q924T4-1", "uniprot_id": "LFNG_RAT", "id": "Q924T4-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLQRCGRRLLLALVGALLACLLVLTADPPPTPVPAERGRRALRSLAGSSGAAPGPGS-RAAVDPGVLVREVHSLSEYFSLLTRARRD------------------------ADPPPGVASRQGDGHPRPPAEVLSPRDVFIAVKTTRKFHRARLDLLFETWISRHKEMTFIFTDGEDEALAKHTG-NVVLTNCSAAHSRQALSCKMAVEYDRFIESGKKWFCHVDDDNYVNLRALLRLLASYPHTQDVYIGKPSLDRPIQATERI-SEHRVRPVHFWFATGGAGFCISRGLALKMGPWASGGHFMSTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTTELHEQVTLSYGMFENKRNAVHIKGPFSVEADPSRFRSIHCHLYPDTPWCPRTAIL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09010-1", "uniprot_id": "LFNG_MOUSE", "id": "O09010-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLQRCGRRLLLALVGALLACLLVLTADPPPTPMPAERGRRALRSLAGSSGGAPASGS-RAAVDPGVLTREVHSLSEYFSLLTRARRD------------------------ADPPPGVASRQGDGHPRPPAEVLSPRDVFIAVKTTRKFHRARLDLLFETWISRHKEMTFIFTDGEDEALAKLTG-NVVLTNCSSAHSRQALSCKMAVEYDRFIESGKKWFCHVDDDNYVNLRALLRLLASYPHTQDVYIGKPSLDRPIQATERI-SEHKVRPVHFWFATGGAGFCISRGLALKMGPWASGGHFMSTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTTELHEQVTLSYGMFENKRNAVHIKGPFSVEADPSRFRSVHCHLYPDTPWCPRSAIF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NES3-1", "uniprot_id": "LFNG_HUMAN", "id": "Q8NES3-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLKRCGRRLLLALAGALLACLLVLTADPPPPPLPAERGRRALRSLAGPAGAAPAPGLGAAAAAPGALVRDVHSLSEYFSLLTRARRD------------------------AGPPPGAAPRPADGHPRPLAEPLAPRDVFIAVKTTKKFHRARLDLLLETWISRHKEMTFIFTDGEDEALARHTG-NVVITNCSAAHSRQALSCKMAVEYDRFIESGRKWFCHVDDDNYVNLRALLRLLASYPHTRDVYVGKPSLDRPIQAMERV-SENKVRPVHFWFATGGAGFCISRGLALKMSPWASGGHFMNTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTSELHEQVTLSYGMFENKRNAVHVKGPFSVEADPSRFRSIHCHLYPDTPWCPRTAIF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHF2-1", "uniprot_id": "LFNG_DANRE", "id": "Q8JHF2-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLKTYRGKVVVSLAGATVTCLGFLLFLSQHQRIQAD-GMQNESEVGLRSLQSLGDSETDDGAQP--EQNAKKGFSAYFSKLTRSRRE------------------------ADKP---SEAPGAATDAPPAEDISADDIFIAVKTTKKFHRSRLDLLLDTWISRNMRQTYIFTDGEDEELKKKIGSHAINTNCSAAHSRQALSCKMAVEYDKFIESGKKWFCHVDDDNYVNTKTLVKLLSNYPHTQDMYIGKPSLDRPIEATERL-GDNKMRPVNFWFATGGAGFCISRGLALKMSPWASGGHFMNTAEKIRLPDDCTIGYIIESVLGVSLTRSSLFHSHLENLQQVSKSEVHKQITLSYGMFENKRNIINMKGAFSVEEDPSRFKSVHCLLYPDTPWCPPQVAY----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24342-1", "uniprot_id": "FNG_DROME", "id": "Q24342-1", "name": "Fringe glycosyltransferase", "aln": "MMSLTVLSPPQRFKRILQAMMLAVAVVYMTLLLYQSAYGYPGIQVPHSQVDALASEAVTTHRDQLLQDYVQSSTPTQPGAGAPAASPTTVIIRKDIRSFNFSDIEVSERPTATLLTELARRSRNGELLRDLSQRAVTATPQPPVTELDDIFISVKTTKNYHDTRLALIIKTWFQLARDQTWFFTDTDDHYYQEKTKGHLINTKCSQGHFRKALCCKMSAELDVFLESGKKWFCHFDDDNYVNVPRLVKLLDEYSPSVDWYLGKPSISSPLEIHLDSKNTTTNKKITFWFATGGAGFCLSRALTLKMLPIAGGGKFISIGDKIRFPDDVTMGFIIEHLLKVPLTVVDNFHSHLEPMEFIRQDTFQDQVSFSYAHMKNQWNVIKVDG-FDMKTDPKRFYSLHCQLFPYFSFCPPR-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *:**.**** * ** *: **.. *:.*** * . : *:** : : **.***:.* * *: * :*:**.*****: *: ** :. * *:*:**:. *:. : ***********:.* *: :* * *. * . : :*** *:*:*:* * : ****** : : . *:::*:. :. * : : * * **.** ::** *:* :** ", "identical_positions": 93, "similar_positions": 62, "identity": "21.83%" }, { "cls_id": "homologset.agr.FB:FBgn0011592", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63155-1", "uniprot_id": "DCC_RAT", "id": "Q63155-1", "name": "Netrin receptor DCC", "aln": "-MENSLGCVWVPKLA-----------------------FVLFGASLLSAHLQVTGFQIKPFTSLHFVSEPSDAVTMRGGNVLLNCSAESDR-----------GVPVIKWK-KDGLILALGMDDRKQQLPNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVMVAGPLRFLSQTESITAFMGDTVLLKCEVIGD-----PMPTIHWQKNQQDLNPIPGDSRVVVLPSGALQISRLQPGDSGVYRCSARNPASTRTGNEAEVRILSDPGL----HRQLYFLQRPSNVIAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQL-RSKK-YSLLGGSNLLISNVTDDDSGTYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECAVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQSSAQLIVPKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------AIPSSS----ILPSAPRDVVPVLVSSRFVRLSWRPPA-EAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLHAVSASPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMET--LEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDP-TDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTMYYFRIQARNAKGVG--PLSDPILFRTLKVEHPDKMANDQ--GRHGDGGYWPVDTNLIDRSTLNEPPIGQMHPPHGSVTPQKNSNLLVITVVTVGVLTVLVVVIVAVICTRRSSAQQRKKRATHSAS----KRKGSQKDLRPPDLWIHHEEMEMKNIEK-PAGTDPAGRGSPIQSCQDLTPVSHSQSESQMGSKSASHSGQDTEEAGSSMSTLERSLAARRATRTKLMIPMEAQSNNPAVVSAIPVPTLESAQYP---GILPSPTCGYPHPQFTLRPVPFPTLSVDRG---FGAGR--TVSEGPTAQQQPMLPPAQP---------EHPSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPM---SAIEPKVPYTPLLSQPGPTLPKTHVKTASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDPASVYEQDDLSEQMASLEGLMKQLNAITGSAF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70211-1", "uniprot_id": "DCC_MOUSE", "id": "P70211-1", "name": "Netrin receptor DCC", "aln": "-MENSLGCVWVPKLA-----------------------FVLFGASLLSAHLQVTGFQIKPFTSLHFVSEPSDAVTMRGGNVLLNCSAESDR-----------GVPVIKWK-KDGLILALGMDDRKQQLPNGSLLIQNILHSRHHKPDEGLYQCEASLADSGSIISRTAKVTVAGPLRFLSQTESITAFMGDTVLLKCEVIGE-----PMPTIHWQKNQQDLNPLPGDSRVVVLPSGALQISRLQPGDSGVYRCSARNPASIRTGNEAEVRILSDPGL----HRQLYFLQRPSNVIAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQL-RSKK-YSLLGGSNLLISNVTDDDSGTYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECAVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQSSAQLIVPKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------AIPSSS----ILPSAPRDVLPVLVSSRFVRLSWRPPA-EAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLHAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNISLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMET--LEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDP-TDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTMYYFRIQARNVKGVG--PLSDPILFRTLKVEHPDKMANDQ--GRHGDGGYWPVDTNLIDRSTLNEPPIGQMHPPHGSVTPQKNSNLLVITVVTVGVLTVLVVVIVAVICTRRSSAQQRKKRATHSVS----KRKGSQKDLRPPDLWIHHEEMEMKNIEK-PTGTDPAGRDSPIQSCQDLTPVSHSQSETQMGSKSASHSGQDTEDAGSSMSTLERSLAARRATRAKLMIPMEAQSSNPAVVSAIPVPTLESAQYP---GILPSPTCGYPHPQFTLRPVPFPTLSVDRG---FGAGRTQSVSEGPTTQQQPMLPPAQP---------EHPSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPM---SAIEPKVPYTPLLSQPGPTLPKTHVKTASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDPASVYEQDDLSEQMASLEGLMKQLNAITGSAF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43146-1", "uniprot_id": "DCC_HUMAN", "id": "P43146-1", "name": "Netrin receptor DCC", "aln": "-MENSLRCVWVPKLA-----------------------FVLFGASLFSAHLQVTGFQIKAFTALRFLSEPSDAVTMRGGNVLLDCSAESDR-----------GVPVIKWK-KDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGE-----PMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGL----HRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQL-RSKK-YSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------AIPSSS----VLPSAPRDVVPVLVSSRFVRLSWRPPA-EAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMET--LEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDP-TDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVG--PLSDPILFRTLKVEHPDKMANDQ--GRHGDGGYWPVDTNLIDRSTLNEPPIGQMHPPHGSVTPQKNSNLLVIIVVTVGVITVLVVVIVAVICTRRSSAQQRKKRATHSAG----KRKGSQKDLRPPDLWIHHEEMEMKNIEK-PSGTDPAGRDSPIQSCQDLTPVSHSQSETQLGSKSTSHSGQDTEEAGSSMSTLERSLAARRAPRAKLMIPMDAQSNNPAVVSAIPVPTLESAQYP---GILPSPTCGYPHPQFTLRPVPFPTLSVDRG---FGAGRSQSVSEGPTTQQPPMLPPSQP---------EHSSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPM---SAIEPKVPYTPLLSQPGPTLPKTHVKTASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDSANVYEQDDLSEQMASLEGLMKQLNAITGSAF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97603-1", "uniprot_id": "NEO1_RAT", "id": "P97603-1", "name": "Neogenin", "aln": "------------------------------------------AAAKNGSPPQSAGASVRTFTPLYFLVEPVDTLSVRGSSVILNCSAYSE------------PSPNIEWK-KDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLAVAGLPRFTSQPEPSSIYVGNSGILNCEVNAD-----LVPFVRWEQNRQ---PLLLDDRIVKLPSGTLVISNATEGDEGLYRCIVESGGPPKFSDEAELKVLQESEE----MLDLVFLMRPSSMIKVIGQSAVLPCVASGLPAPVIRWMKNEDVLDT-ESSGRLALLAGGSLEISDVTEDDAGTYFCVADNGNKTIEAQAELTVQVPPEFLKQPANIYARESMDIVFECEVTGKPAPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEH----------------------------------------------------------------------------------------------------------------------------------------------------------------------APATT---GPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETVVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDESRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTD--TSEVDLFVIN-APYTPVPDP-TPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG--PMSEAVQFRTPKADSSDKMPNDQALGSAGKGGR------LPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSIGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDK-SPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMS-------TLAGRRGMRPKMMMPFDSQ-PPQ-----------------------------------------------------QSVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPG--PPIYDPALPSTPLLSQQALNHHLHSVKTASIGTLGRSRPP-MPVVVPSAPEVQE-ATRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97798-1", "uniprot_id": "NEO1_MOUSE", "id": "P97798-1", "name": "Neogenin", "aln": "MAAEREAGRLLCTSSSRRCCPPPPLLLLLPLLLLLGRPASGAAATKSGSPPQSAGASVRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSE------------PSPNIEWK-KDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNCEVNAD-----LVPFVRWEQNRQ---PLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEE----IVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDT-ESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPT--------------------------------------------------------------------------------------------------------------------------------------------------SLTSATTDHLAPATT---GPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTD--TSEVDLFVIN-APYTPVPDP-TPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG--PMSEAVQFRTPKADSSDKMPNDQALGSAGKGSR------LPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVVIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDK-SPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMS-------TLAGRRGMRPKMMMPFDSQ-PPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPG--PPLYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPP-MPVVVPSAPEVQE-TTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92859-1", "uniprot_id": "NEO1_HUMAN", "id": "Q92859-1", "name": "Neogenin", "aln": "MAAERGARRLLSTPS-----------FWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSE------------PSPKIEWK-KDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNAD-----LVPFVRWEQNRQ---PLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEV----ISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDT-ESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEH----------------------------------------------------------------------------------------------------------------------------------------------------------------------APATT---GPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTD--TSEVDLFVIN-APYTPVPDP-TPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG--PMSEAVQFRTPKADSSDKMPNDQASGSGGKGSR------LPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNSKDVKPPDLWIHHERLELKPIDK-SPDPNPIMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMS-------TLAGRRGMRPKMMMPFDSQ-PPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPGSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPG--PPTYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPP-MPVVVPSAPEVQE-TTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUL1-1", "uniprot_id": "A0A8M3AUL1_DANRE", "id": "A0A8M3AUL1-1", "name": "Neogenin", "aln": "-MAERGARLLLSLFC--------------------------LTIT-VSHAEK--GSAVRNFSPFWFSTEPSDTLAVRGAPVLLNCSVHSE------------SPAKIEWK-KDGSFLSLASDERRQVLADGSLLISSVVHSKHNKPDEGVYQCVATIDNLGTIISRTARLNVAGIARFLSQPEMASVRVGDSQVLSCEVNPD-----LVSFIRWEQNKE---AVELDHRVFSLPSGALVISNATETDAGLYRCVIDNAGPTKTSEEAQLHILTETGE----ERTLEFLQEPQHVSKLVGESVLLPCVVTGYPTPEITWMYKDQLIE--DSSGRFEILGGGSLRIFNLTEEDAGVYNCLAENTNGSIEAQAELTLKDSPQFLKKPVNVFAHEATDVIFECEVSGSPSPTIKWVKNGDAVIPSDYFKIIKEQNLQVLGLVKSDEGFYQCLAENDAGNVQSSAQLVILDQDVTLPLPRPT--------------------------------------------------------------------------------------------------------------------------------------------------SLTRATTDRLMPGSRGGAGPTPSAPRDVVASLVSTRFLKLTWRLPA-EPHGDDVTYSVYYSLEGTNRERIVNTSRPGEMQVTIQNLMPDTKYAFRVVAHNKNGPGESSVPLKVETQPEVQVPGPAPNLHAVVMSPSTVSLSWDVPLIGNGEIQNYKIYYMEKGMDSEQDLDVNTLSYTMTGLKKFTEYSFRLVAYNKHGPGVSTEDISVRTYSDVPSSPPQNMTVEVLNSKSLMIRWQPPPADAQNGEITGYKIRYRKGTRKSEVAE-ITSGSQLYQLIDGLQRGTEYMLRVSAMTVNGTGPATDWTTAETFESDLDESRVPDVPSSLHVRSLVNSIVVSWTPPENQDIVVRGYSISYGIGSPHAQTIKVDYKQRYYTIENLNPNSHYVITLKAFNNVGEGIPVYESAITRPQSDPIDPDVDLYELFHAPYTPVPDP-IPMLPPVGVQASVLNQDTIKVTWADNSLPKNQKITDARYYTVRWKTNIPANTKFKVANTTTLFHTVTGLKPNTLYEFSVMVTKGRRTSTWSMTAHGTTFESIPSSPPKDVTVVSKEGRPKTIIVNWQPPSEANGKITGYIIYYSTDVKAEVHDWVIEPVVGNRLTHQIQELTLDTTYYFKIQARNSKGMG--PMSEAVQFRTPKAESSDKMANDQAPGISVKQGRP----SAPDNGFGS-PGKPDMSG------TGDNHILVIVIIVSVGAFTIIVVVVGAFLCTRRTTTQQKKKRAACKSANGSHKYKGNSKDLKPPDLWIHHERLELKPIDK-SPEPNPVMTDTPIPRTSQDITPVDGSMDPMLQ-RRNSYRGHESEDSMS-------TLAGRRGMRPKMMMPFDAQ-PPQPVISAHPIHSLDNHHHHYHLGSLASPTRSYLHHQSSTRSIATPISHLDRAESTESVRNTPNAELLPPS-GQPSCTTDLS---ETDISFHSSAAEEEPAFATPTAHVRPTHPLKSFAVPAIPAHAMYDS---AALPSTPLLSQTGP----HSVKTASIGTLGRTRTP-MPVIVPNAPDVSE-GCRLHEDAGSNYETDELSEEMAHLEGLMKDLNAITTA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B6X0-1", "uniprot_id": "A0A8M3B6X0_DANRE", "id": "A0A8M3B6X0-1", "name": "", "aln": "-MAEREQRLLVFFTS--------------------------LIVLRFGGADK--GSAIRGFTPFRFSVEPVDVLAVRGLPAVLNCSAISD------------APVRVEWK-KDGTFLNLVADDRRRQLADGSLLISTVVHSKHNKPDEGVYQCVATIDNLGTISSRTARLTVAGLPRFLSQPEGVSVRSGGTEMLSCEVTEE-----LVPFTRWDRDAR---PVELDSRVIQLPSGALVISNASQADAGLYRCTIDGLGPPKTTEEAELQVVTDSGA----GEKLETLQGPVAVAKVVGESVLLPCVMKGHPIPAIRWTFNDQPIE--EAHERFSVIGGGSLQIVNLTEEDAGIYVCQADSGNMTSEIQAELTVHVPPRFLTRPSNTYAQESMDIIFECDVTGSPPPTVKWMKDGDTVIPSDYFRIVKQHNLQVLGLVKSDEGFYQCLAENDAGNVQASAQLIILDIDVALPSTVP---------------------------------------------------------------------------------------------------------------------------------------------------SLTAATTDHVASSGSERSGPTPSAPRDVVASLVSTRFIKLTWRLPA-EPHGENITYSVFYSLDGTNRERVENTSAPGEMQVTIQNLIPDTKYSFRVVASNANGPGESSAPLTVATQLEVQVPGPAPNLQVVSVGSSTVSLSWERPITGNGEIQTYKLFYIEKGQESEQDVDVSGLSYTMTSLKKFTEYSFRVVAYNKHGPGVSTEDVTVRTLSDVPSAAPQNLTLDVLNSTSIMVRWQPPPAGSLNGELTGYKLRYRKGLRRADAVE-IST-MQIFQLIDGLERGKVYTVRVSATTVNGTGPATEWSAAETFESDLDESQVPGVPSSLHVRPLVNRIVVSWTPPENQEVLVRGYKIGYGIGSPHAHTVTLDYKQRFYSIDNLDASSHYVITLKAYNNMGEGVPIYNSATTRPQSDPVDPDIDFYELFNNPYTPAPDP-TPMLPPVGVQASVLSHDTVKVSWADNSLAKNQKITDARYYTIRWKTNIPANTKYKMANTTSLFHTVSALKPNTLYEFSVMVTKNRRSSTWSMTAHSTTHESIPSSAPKDVTVISKEGNPRIININWQPPTEANGKITGYIIYYSTDVNAEVHDWVVEPVVGNRLTHQIQGLTLDTSYFFKIQARNSKGMG--PMSDAVQFRTPKAEPSDKMSSDQ--GLQVKPGHP----TLPEHGSGSNMDKQGITG------SQENHILVIVVIVSVGVFTIIAVVVGAVLCTRRSNSHQKKKRAACKSSTSSHKYKSSSKDLKPPDLWIHHERLELKPMDK-SPEPNPVMTETPIPRSVQ---------EPAVE-TSHQRRGHDMEDSVS-------TLPGRRAVRPKMMMPFDSQ-PPQPVISAHPIHSLDHLHHHHHHYHLPP--RGYLHHQISLRAPATTHTHSERAA--ESARNQPAAPEPPVAPSQPITTAELQ---KPTEVIK---EEESPGVNPPTAHVRPTHPLKSFAVPTVTVSAHSPSTYDSTLPSTPLLAQPG-----AAGKTASIGTLSRARAP-MAVTVPSAPDQSE-TSKMLDMT---FETDELSEEMAHLEGLMKDLNAITTG----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z920-1", "uniprot_id": "A1Z920_DROME", "id": "A1Z920-1", "name": "", "aln": "-MAITTNRSSRTLWN----------------------------WLLSSCLIFQLIGSSLASQALSFTLEPQDAVVPEGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFRTQLKNGSLYISSVEE---NRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLP--LPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGDLITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAGSVHAAARLRVVPQGVKIKKRKSQGHSTKSLQTFDNLTKRRKPFNSGEQLRTKSGGSFPFPDEDDDLDDNDSGTTRLRIPSGKLPKFEQPLNDRRFNILNAGSALPLDNQSKSYEDDDDDYDEDDPAKEALLEAYKQGEDAHKILDSWQQSKSKKSQQQKQSPASPDSPEQDPSVPHPGGKPLDSGLQARLPSQPRDLVAQIVKSRFVTLSWVEPL-QNAGDVVYYTVYYKMNNSEREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPPRNFEGYARSHKEIYVKWEEPTVTNGEILKYRVYYSENDSGADLYHDSTALEAVLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNNVTLEVTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFKDAPQVKS--TPANIRYFELSNLDRNAEYQVKIAAMTVNGSGPFTEWNRANTLENDLDETQVPGKPIWISIHPGANNIALHWGPPQHPEIKIRNYVLGWGRGIPDENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEP-------------------VDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDNRHYTVSYG--ITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQARTTKGANNAPFSALVSYTTSAAVTMQEPDTIAK--------------------------------------GIDNEKLLYIIIAATAVVLLVVLLGVLLLCRRKPQSSPEHTKKSYQKN--------NVGVPKPPDLWIHHDQMELKNIDKGLHTVTPVCSDGASSSGALTLPRSVVHSEYEVETPVPGHVTN--------------SLDKRSYVPGYMTTSMNGT-------------------------------MERPQYPRTQYSHQNRSHMTMEAGLSQQSLTQPQSNSMAQTPEHPYGGYDAN-------FCNAGNAAAGNGCVSTIESSKRGHPLKSFSVPGPPPTG----GATPVTKHTPAVTIRPQNQSPYKKPSFSAATPNRLQGG--GSVVHSTDEIQR--------LAPSTSTEELNQEMANLEGLMKDLSAITANEFEC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: * ** *.: .* .:*:*: :. :.*: ** * : * : * :*** *..: . :: * *** : . *:* **.* : :. : .: * . : * : :* :: . *:. **.* * *.. * * *:* . .. : .:.::.: . * * *. . * * .* * * . * :: ::. . * * . : *:* * * . . . .* : : * *:. * : * * : ::* : *.* *.:.*:*:** : *.**:::: **::**:::** *::**:. * .*..::.*:* : . ** ***::. :*.:**: *:* * : *: ::*::. :. **: *. .. *:.: .* * * *:* * . *.* ** *: * ** *:::.** *:. . . : :.*: * ** : *::: * . : : . : *: .*:* : .:.:*: * * *: :: * * *..** .*:*::::* .* *: : * **. ** :****:*:** : : .*::. * .:::* *:**:** ::* *:* *.****::** * : ::. .. * : * ** : :: :*.* :.:* * * .*: :. .:*:: :..*:.. .**::*:* * *:* *:*:. ** * *: ***::* :. .:: : * *. : *:*: :: * **: : :... ::: ::* * . *:*** ***:* *.*.** *:***:. :*.: * :.*:::** * .* : :.* ** .: *:**.* ::*: * . ** :*.. *:. : *. * *:*::***. ** . *:* : : * . :: . : :: : :.: ... ::.:: .:* *:. : .:.: : . . :********:.:*:* ::* * . : : : :* * : .::. . : . . . : ***:**: * . . ** :: : * . .: : * .: : .. . ::*.::** ******:*.*** ", "identical_positions": 298, "similar_positions": 394, "identity": "17.57%" }, { "cls_id": "homologset.agr.FB:FBgn0011596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80U63-1", "uniprot_id": "MFN2_MOUSE", "id": "Q80U63-1", "name": "Mitofusin-2", "aln": "----------------------------------------------------------------------MSLLFSRCNSIVTVKKDKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESASFLEDTHRNTELDP---------------------VTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHE------------AFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG----SMVSVMWPNSK----CPLLKD---DLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWD-ASASEPEYMEEVRRQHMERCTSFLVDELGVVD--RAQAG-DRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQD---YKLRIKQITEEVERQVSTAMAEEIRRLS-VLVDEYQMDFHPSP-VVLKVYKNELHRHIEEGLGRNLSDRCSTAIASSLQTMQQDMIDGLKPLLPVSMRNQIDMLVPRQCFSLSYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALLGYSDQVQRPLPLTPANPSMP--PLPQSSLTQEELMVSMVTGL--ASLTSRTSMGILVVGGVVWKAVG-----WRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEYASEKLQLIISYTGSNCSHQVQQELSGTFAHLCQQVDITRDNLEQEIAAMNKKVEALDSLQSRAKLLRNKAGWLDSELNMFTHQYLQPSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R500-1", "uniprot_id": "MFN2_RAT", "id": "Q8R500-1", "name": "Mitofusin-2", "aln": "----------------------------------------------------------------------MSLLFSRCNSIVTVKKDKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESAGFLEDTHRNTELDP---------------------VTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHE------------AFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG----SLVSVMWPNSK----CPLLKD---GLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWD-ASASEPEYMEEVRRQHMERCTSFLVDELGVVD--RAQAG-DRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHIAAQEQRVYCLEMREERQDRLRFIDKQLELLAQD---YKLRIKQMTEEVERQVSTAMAEEIRRLS-VLVDEYQMDFHPSP-VVLKVYKNELHRHIEEGLGRNMSDRCSTAIASSLQTMQQDMIDGLKPLLPVSVRNQIDMLVPRQCFSLSYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALLGYNDQVQRPLPLTPANPSMP--PLPQGSLTQEELMVSMVTGL--ASLTSRTSMGILVVGGVVWKAVG-----WRLIALSFGLYGLLYVYERLTWTTRAKERAFKRQFVEYASEKLQLIISYTGSNCSHQVQQELSGTFAHLCQQVDITRDNLEQEIAAMNKKVEALDSLQSKAKLLRNKAGWLDSELNMFIHQYLQPSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95140-1", "uniprot_id": "MFN2_HUMAN", "id": "O95140-1", "name": "Mitofusin-2", "aln": "----------------------------------------------------------------------MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDTYRNAELDP---------------------VTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHE------------AFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAG----SLVSVMWPNSK----CPLLKD---DLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWD-ASASEPEYMEEVRRQHMERCTSFLVDELGVVD--RSQAG-DRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQD---YKLRIKQITEEVERQVSTAMAEEIRRLS-VLVDDYQMDFHPSP-VVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMP--PLPQGSLTQEEFMVSMVTGL--ASLTSRTSMGILVVGGVVWKAVG-----WRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJP0-1", "uniprot_id": "A0A8M2BJP0_DANRE", "id": "A0A8M2BJP0-1", "name": "", "aln": "----------------------------------------------------------------------MSLVFPRPNTSVIGKKDKRLMAEVNASPLKHFVTAKKKINGIFEQLGAYIKESSAFLEETYSNEELDP---------------------VTTEEQVAEVRGYLSKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNE------------SFLLTEGSDERKSVKTVNQLAHALHQDEDLDAG----SLVCVMWPKAK----CALLRD---DLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWD-ASANEPEYMEEVRRQHMDRCTSFLVDELRVVD--RSHAG-DRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNFERRFEECISQSAVKTKFEQHTTRAKQISEALRLIMDSVHIAAQEQRIHCLEMKEEREDRLEFIDKQLDLLTLD---CKSKIKKITEEVEKQVSNAMAEEIRRLA-VLVDDFHMDFHPSP-VVLKVYKNELHRHIEEGLGRNMSERCSSAITVALQTTQTDMIDGLKPLLPITIREQVDKMVPRQCFALSYDLNCDKLCSDFQEDIGFHFSLGWTMLVNRFLGPKNTRRALMGYNDQVPRSLAITPVSTSMP--PFPQGSMTQEELMVSMVTGL--ASLTSRTSMGIIVVGGVIWKAVG-----WRLIALSVGLYGLLYVYERLTWTTRAKERTFKRQFVDYASEKLQLIVSYTGSNCSHQVQQELASTFSQLCQQVDVTRQQLEDEIGDLNSKIEQLDTLQSKAKLLRNKAGWLDSELNMFIQQYLQQGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18412-1", "uniprot_id": "FZO_DROME", "id": "O18412-1", "name": "Transmembrane GTPase fzo", "aln": "--------------------------------------------------------------------------MAESDSGESTSSVSSFISSSSSSRLSEFVDAKTELQDIYHDLSNYLSNFLTILEETVLLK---------------------------DRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNE------------TEHVKVEQEDEHMELSALSQLASAHSPGALKPS----TLLQVNMAKNR----CSILDY---DVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYS--TAQEAWERIYHVSALEALHIRNGQITNP-------SGQTQQRYQEFLRFENDFSNCLAVSALKTKFGPHLLSAQKILNQLKSTLICPFIEKVSR--LIDENKERRANLNAEIEDWLILMQEDREALQYCFEELTEMTQRVGRCVLNDQIKTLIPSSVLSFSQPFHP----EFPAQIGQYQRSLCAHLDKLLEDRVLQCLSIPLQRKILDIEKEIG--LPIAEN--------SCDWQLIYGLDCQSYMSDFQPDLRFRFSLGFTALWHRLEG----NLPLHASPFRIQKLQNGHKKCSPLP--PLVNG--NHWQMLESLVK--------SKGSLGTVLLSAMAIRSFN-----WPIVLILGGLVGSFYIYEYAAWTTAAQERSFKSQYARLLQQRLRSDVQQTVSGFELQLRQHLATVRNCWEAQSNETLNDLNVRTAELTKQIQSMEVLQLSLKKFRDKGQLLASRLGDFQETYLTKS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38297-1", "uniprot_id": "FZO1_YEAST", "id": "P38297-1", "name": "Mitofusin FZO1", "aln": "MSEGKQQFKDSNKPHKDSTDQDDDAATIVPQTLTYSRNEGHFLGSNFHGVTDDRTTLFDGEEGRREDDLLPSLRSSNSKAHLISSQLSQWNYNNNRVLLKRSILKTQAFMDQLQEENNIRPIFIAANDEREKLHVLQLNIKLDGQYNTKEKNGFNIEKKALSKLFHSQIVSVTNHLNALKKRVDDVSSKVFITGDVNTGKSALCNSLLKQRLLPEDQLPCTNVFSEILEARENDGIEEVHAIPLNIAPTLKEAIDMYSIQNPKTYEIHTLKELPDLVPQNGKYALLKIYIKDDKRPASTSLLRNGTVDISLIDSPGLNMDSLQTAEVMSRQEEIDLVIFVVNAENQLTLSAKEFISLASR--EKKLMFFVVKKFD-------------KIRDKQRCKELILKQIRDLSPETYKRAADFVHFVSKNGDELPHYHNENDNEDHGDRKPDDDPYSSSDPDPDFDSLEDSLRNFVLKKRSLSKLLPAKTYLSKLLSDIIMISKS----------NMKMYSEEEIKINEQLETLRPEILSARAKCNDLTTSVDQMAEQTITMTYNNTKEALLNALDVPLHEYPKYQGLGQIYDFIFSTEAFIANQIDESIGSSELFAKQKTDLLVKKIYEIGKNELGDDFMCERVFRSELMFRKRKHLIGKRLKVSLSITDLFAPTWKGFLSYLSWQKPVTAPLPDIEGQTNEGQIGLMKYLGLKNYPLTQYWSRPSLLFTSKIPTLTLYFLGSTKVVGNIILNGIKLSSWSSLKKLSVPVIVVGSLLGLTYLIHDLPRALPMN-LSIKYKRKLQELDYIHLNAQRTSN----EVRDVLRVPTREILRSCEIIMDKKQITKKELENKKESN---LLSIKFFQSLYEGTVAQKLMVEEINLDID-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: .. . . . *.. : . : . .: . :: . .: . .:: .: : : ** : * ...***:: *::* :::**. *. * .: :: : :. : . : :. * . ::: : . : .:* .: *:*:**::: : : . : *:.::* *:*. : : *: . . :*:: :::* : :. :** .:::.:: . : . : :..** : : . . : :.:.: .:*.: : *: . : : : : *:. * : : : :.:* .:: .: . : :* : : . :.: . . * : . : . ... .: *: :. : : .* : . : *: : :: * : * :* :::..: : . : : .* * *: . . : : ::* : : :: . * . :::: * . : :. : : .: : * ::. :. . . * . ", "identical_positions": 51, "similar_positions": 225, "identity": "5.74%" }, { "cls_id": "homologset.agr.FB:FBgn0011603", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1NER2-1", "uniprot_id": "A0A8M1NER2_DANRE", "id": "A0A8M1NER2-1", "name": "Transporter", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMG---------------LGSENK------------------------TVSTS------------------------------------SKFALQQLGEGKEEEE---LARTTTDRAEATRLAN-------------------VEQQAAEPRE-TWGRRLEFVLATIGYAVGLGNVWRFPYLCYRSGGGAFLIPYMIMLFLCGIPLLFMEFTVGQYTRLGPVHALAQICPLFKGVGLATVVISYVLCTYYNVLMTWALYYLLHSFSPSLPWQSCNNTWNTVANCSTGFPGN----ATHLQSASQQFFDHKVLEMTSGIERAGGVRWELFGLLVLAWGIVYFCIFKGVKSTGKVVYFTATFPYFILFALLVNNVQLPGAKNGILFFLMPNWSKLLEVQVWVNAAAQIFNSIGISFGSMISMASYNKYNNNILRDTFIVSLANSATSIVAGFVIFSAIGYMAHIHNLPVDDIATDGPGLVFVVYPEVFSTMPVSQLWAPLFFIMLLCLGLDSQFAMVEVAVTFIMDGFGRKALKVFKRKELIVLAVCSFGFLLGIPHITRGGIYVFQLMDHYTAVVSLMFLAFFEVLAVTLIFGVKRLSVMVENMLGKKPNLFFRICWQYLSPMLVLGILISSIVQYTPARYGKS-YTYPLWAELLGWFISLVSIIWIP-LGALHELWTTEGSLLQRLKKSITPTVDLESVS-------EKPSTESIALFNAP--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR07-1", "uniprot_id": "INE_DROME", "id": "Q9VR07-1", "name": "Sodium- and chloride-dependent GABA transporter ine", "aln": "MAENKDVSQVLNTTPDQVVINRAPPTGLAPLRHSQLSDSGAESCYEGDEQARLIRSSSSRAHKFIIIPATPGTPPGSGAVAGPLPFRQTSSTTSLAAMAAALHKQSPLRHTSVRTRPSSEVLQPGQVLANQPTAAVSTSTVTFTIDDCNEEGDAIPAAASVPAPVTMPAISPTPATLTCTTTTTMAGDSVAVSPLSMELKSRLGSHHSSMRSVVSGYLPGLSDSSGNLVGGVSMATSGLQAPNPLYMQPQASLSGSSYHFHELAGNQIYSDVTSVRSLASIGIGSTDGRKLVIRRVPTTANELFDMVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQFMLAQEMATVYKPTNPHLLNLGQKCGYNAMQASPSHAEAGGPCGQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ***.:. :::** * :* .:* *. : . : *..* * :.* * :**: *..:::**** ***:***********:**:****.**:** *:**:*.*******::***** **: **.*:******.***:**:*:::.***.*:: :::**:: **...:** .*** *** . * . ::.*::**::***:::.*:* .* :*****. *: ** :***. :*.:**:.** *******:.::: *:*. * * ** :*: **: *:**:* :.:**:***:* ***:**:******:**************. ** .* **::.*:. **::* :* :* * *: ****::*****:.::.** :**** :**:*******:****:***.** * *** * : : :*::** ** :. *:*:*:* :**** *******:* *::***** :::*:: ::*. *** *::* ** *.:::* ** *.* *::.* : *:::* . * :. **** ** :**::: .*:* ** ..:: * :: .:: :*::::: *.: .:. : *. *.: * : ", "identical_positions": 289, "similar_positions": 197, "identity": "30.65%" }, { "cls_id": "homologset.agr.FB:FBgn0011604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQQ5-1", "uniprot_id": "A0A8I5ZQQ5_RAT", "id": "A0A8I5ZQQ5-1", "name": "", "aln": "------------------MSSTAEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPSATGAGPADTEMEEVFDDGSPGKQ-KEIQEPDPTYEEKMQ-----TDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRV-KKDEKQNLLSVGDYRHRRTEQEEDEELLT----ESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAGPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVE-GKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTN-KGK-NYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGP-----KPSTQKRKMDGAPDGRGRKKKLKL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZW3-1", "uniprot_id": "SMCA5_MOUSE", "id": "Q91ZW3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "------------------MSSAVEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQ-KEIQEPDPTYEEKMQ-----TDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRV-KKDEKQNLLSVGDYRHRRTEQEEDEELLT----ESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RSPDLP---------NAAQAQ------------KEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVE-GKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTN-KGK-NYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGP-----KPSTQKRKMDGAPDGRGRKKKLKL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60264-1", "uniprot_id": "SMCA5_HUMAN", "id": "O60264-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "------------------MSSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQ-KEIQEPDPTYEEKMQ-----TDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRI-KKDEKQNLLSVGDYRHRRTEQEEDEELLT----ESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQ-KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGR--LVDQNLNKIGKDEMLQMIRHGATHVFASKESEIT-------------DEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDT-----ESSVYNFEGEDYREKQKIAFT--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVP--------RNPELP---------NAAQAQ------------KEEQLKIDEAESLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVE-GKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTN-KGK-NYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIEREN---MELEEKEKAEKKKRGP-----KPSTQKRKMDGAPDGRGRKKKLKL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGB8-1", "uniprot_id": "SMCA1_MOUSE", "id": "Q6PGB8-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1", "aln": "----------------MEPDTATEAATVAVSDARATVVVVEDEQPGPSTFKEEGAAAAATEGTTATEKGEKK-EKITSPFQLKLAAKASKSEKEMDPEYEEKMVNMPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRV-KKDDKQSLISVGDYRHRRTEQEEDEELLS----ESRKTSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVGNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYSRLDGQTPHEEREEAIDAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRHGATHVFACKESELT-------------DEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDL-----EQSLYKFEGEDYREKQKLGTV--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPEIP---------NPAIAQ------------REEQKKIDGAEPLTPQETEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVE-GKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTS-KGK-NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKEN---MEIEERERAEKKKRAT-----KTPMVKFSAFS-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YCJ3-1", "uniprot_id": "A0A8I5YCJ3_RAT", "id": "A0A8I5YCJ3-1", "name": "", "aln": "----------------MEPDTATEAATVAASDARATIVVLEDEQPGPSTFKEEGAAAAATEATTATEKGEKK-EKITSPFQLKLAAKTSKSEKEMDPEYEEKMVNIPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRV-KKDDKQSLISVGDYRHRRTEQEEDEELLS----ESRKTSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNFPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRHGATHVFACKESELT-------------DEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDL-----EQSLYKFEGEDYREKQKLGTV--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKVPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPELP---------NPAIAQ------------REEQKKIDGAEPLTPQESEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNVAREVE-GKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTS-KGK-NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKEN---MEIEERERAEKKKRAT-----KTPMIEEESHHKRTSLLFEEHVVRNSLVTRLSI---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28370-2", "uniprot_id": "SMCA1_HUMAN", "id": "P28370-2", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1", "aln": "----------------MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKNVSSFQLKLAAKAPKSEKEMDPEYEEKMK-----ADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLGRPRI-KKDEKQSLISAGDYRHRRTEQEEDEELLS----ESRKTSNVCIRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQ-KLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSG--KMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGR--LIDQQSNKLAKEEMLQMIRHGATHVFASKESELT-------------DEDITTILERGEKKTAEMNERLQKMGESSLRNFRMDI-----EQSLYKFEGEDYREKQKLGMV--EWIEPPKRERK---ANYAVDAYFREALR------VSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVP--------RNPDIP---------NPALAQ------------REEQKKIDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVE-GKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTS-KGK-NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKEN---MEIEERERAEKKKRAT-----KTPMVKFSAFS-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24368-1", "uniprot_id": "ISWI_DROME", "id": "Q24368-1", "name": "Chromatin-remodeling complex ATPase chain Iswi", "aln": "-------------------MSKTDTAAVEATE--------------------ENSNETTSDAATSSSG-------------------------EKEAEFDNKIE-----ADRSRRFDFLLKQTEIFTHFMTNSA-KSPTKPK----GRPKK-IKD-KDKEKDVADHRHRKTEQEEDEELLA----EDS-ATKEIFRFDASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDD-ALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAG--KVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGR--LVDNRSNQLNKDEMLNIIRFGANQVFSSKETDIT-------------DEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALG-NWIEPPKRERK---ANYAVDAYFREALR------VSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVP--------KNTELGS--------DATKVQ------------REEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDIDNIAKDVE-GKTPEEVIEYNAVFWERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYGNN-KGK-NYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLITLIEREN---IELEEKERAEKKKKAP-----KGSVSAGSGSASSNTPAPAPQPKASQKRKSEVVATSSNSKKKKK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08773-1", "uniprot_id": "ISW2_YEAST", "id": "Q08773-1", "name": "ISWI chromatin-remodeling complex ATPase ISW2", "aln": "---------------------MTTQQEEQRSDTKNSKSESPSEVLVDTLDSKSNGSSDDDNIGQSEELSDKEIYTVEDRPPEYWAQRKKKFVLDVDPKYAKQKD----KSDTYKRFKYLLGVTDLFRHFIGIKAKHDKNIQKLLKQLDSDANKLSKSHSTVSSSSRHHRKTEKEEDAELMADEEEEIVDTYQEDIFVSESPSFVKSGKLRDYQVQGLNWLISLHENKLSGILADEMGLGKTLQTISFLGYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWTPNVNVLVLHGDKDTRADIVRNIILEARFDVLITSYEMVIREKNALKRLAWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFEQNNSEQDQEIVIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEKDIDAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLIFNSGKMIILDKLLKRLKEKGSRVLIFSQMSRLLDILEDYCYFRDFEYCRIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGT--GKKTASLGNSKDDLLDMIQFGAKNMFEKKASKVTV------------DADIDDILKKGEQKTQELNAKYQSLGLDDLQKFNGIE-----NQSAYEWNGKSFQKKSNDKVV--EWINPSRRERRREQTTYSVDDYYKEIIGGGSKSASKQTPQPKAPRAPKVIHGQDFQFFPKELDALQEKEQLYFKKKVNYKVTSYDITGDIRNEGSDAEEEEGEYKNAANTEGHKGHEELKRRIEEEQEKINSAPDFTQEDELRKQELISKAFTNWNKRDFMAFINACAKYGRDDMENIKKSID-SKTPEEVEVYAKIFWERLKEINGWEKYLHNVELGEKKNEKLKFQETLLRQKIEQCKHPLHELIIQYPPN-NARRTYNTLEDKFLLLAVNKYGLRADKLYEKLKQEIMMSDLFTFDWFIKTRTVHELSKRVHTLLTLIVREY---EQPDANKKKRSRTSATRE---DTPLSQNESTRASTVPNLPTTMVTNQKDTNDHVDKRTKIDQEA-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38144-1", "uniprot_id": "ISW1_YEAST", "id": "P38144-1", "name": "ISWI chromatin-remodeling complex ATPase ISW1", "aln": "MAYMLAIANFHFFKFYTRMRKKHENNSCNEKDKDENLFKIILAIFLQEKKKYDCISSGSIMTASEEYLENLKPFQVGLPPHDPESNKKRYLLKDANGKKFDLEG-------TTKRFEHLLSLSGLFKHFIESKAAKDPKFRQVLDVLEENK---ANGKGKGKHQDVRRRKTEHEEDAELLK--EEDSDDDESIEFQFRESPAYVN-GQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDLDAVNGSNGSKESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTSLKKKENKADSKDALLSMIQHGAADVFKSGTSTGSAGTPEPGSGEKGDDIDLDELLLKSENKTKSLNAKYETLGLDDLQKFNQDS--------AYEWNGQDFKKKIQRDIISPLLLNPTKRERK---ENYSIDNYYKDVLN------TGRSSTPSHPRMPKPHVFHSHQLQPPQLKVLYEKERMWTAKKTGYVPT--MDDVKAAYGDISD--------EEEKKQ----------KLELLKLSVNNSQPLTEEEEKMKADWESEGFTNWNKLEFRKFITVSGKYGRNSIQAIARELAPGKTLEEVRAYAKAFWSNIERIEDYEKYLKIIENEEEKIKRVKMQQEALRRKLSEYKNPFFDLKLKHPPSSNNKRTYSEEEDRFILLMLFKYGLDRDDVYELVRDEIRDCPLFELDFYFRSRTPVELARRGNTLLQCLEKEFNAGIVLDDATKDRMKKEDENGKRIREEFADQTANEKENVDGVESKKAKIEDTSNVGTEQLVAEKIPENETTH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . .**..** : :* **: * : . . . . ::*:**:*** **: : . . **:::: * :* **::*:**::**::* : ****************::***::: .: **.:::.*****.** *: :* * :. . : **:: * :::. :: :** ::***: *:**. :*:: *.*::**********:* **:::* * : ****:*************:********:*..:: **.**. :. *: :: :** **.******:*::**. * ** * ::::*::.** .**. :* **:* :*.: : * ** **:****** ******:*********** *:: *:.*: ***** :::*:**********:*:******** :*.::*.*:**.*.*::* *: :* :* **:*:*:**********.:**.*:::******* *************.* *:*:*::*:.::**:::*** *****.:*** . . *: :*.:*:.** .:* : : * *: :* :. ** . : ..:* ..*:.* *:::*:.:::* : ::*.:***: .*::* *::: : .. *. ** ** :..*: * .* * ::* : *. .* . : : . : .:: : :. :: * . ::.** *.* :* **.. *:**:.:: : :.: .*: *** * **.. .::. *: : :* * : :: : * *: . : *:.:* :.: . : : .*. **:*:: : * *: :.:*: :: : . * :*:::::** *: :* :**: : :* : : . :. ", "identical_positions": 345, "similar_positions": 312, "identity": "29.26%" }, { "cls_id": "homologset.agr.FB:FBgn0011606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VIQ3-1", "uniprot_id": "KIF4B_HUMAN", "id": "Q2VIQ3-1", "name": "Chromosome-associated kinesin KIF4B", "aln": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLS-FVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDKKS-DFEFTLKVSYLEIYNEEILDLLCPSREKA-QINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQ----------AHGGTLPGSINAEPSEN--------LQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSP----ETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHG-----KEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQK-HLPNDTLLSPDSSFEYIPPK----PKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRN----RQQGKDSLGTVEQTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGATEYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O95239-1", "uniprot_id": "KIF4A_HUMAN", "id": "O95239-1", "name": "Chromosome-associated kinesin KIF4A", "aln": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLS-FVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKS-DFEFTLKVSYLEIYNEEILDLLCPSREKA-QINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQ----------AHGGTLPGSITVEPSEN--------LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSP----ETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRG-----MEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQK-HLPKDTLLSPDSSFEYVPPK----PKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGD--DDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRN----RQQGKDSLGTVERTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PSJ3-1", "uniprot_id": "E9PSJ3_RAT", "id": "E9PSJ3-1", "name": "", "aln": "MKEEVKGIPVRVALRCRPLVSKEINEGCQTCLS-FVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKT-DFEFTLKVSYLEIYNEEILDLLCSSREKASQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQVLLLQ----------AHGGTLPGNINVKPSEN--------LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLAETLEDQEVKENIEIICNLQQAIARLSDEAVACMTATIDTAGEVDTQEQSSP----DTSRSSDVFSTQHALRQAQMSKELIELNKELALKEALAKKMTQNDNQLQPIQFQYQDNIKNLELEVLSLQKEKEELVLELQTAKKDVNQAKLSERRRKRLQELEGQIAELKKKLHEQSKLLKLKETTELTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQSRG-----MEGTAARMKSWLGNEIEVMVSTEEAKRHLNDLLEERKILAQDVAQLKEKRESGENPPPKLRRRTFSRDEVHGQDSGAEDSISKQIESLESELELRSAQIADLQQKLLDAESEDQPKQRWENIATILEAKCAIKYLVGELVSSKIQVSKLESGLSQSKASCIEVQKMLFEEQNHFAKIETELKEELVRVEQQHQEKVLYLLSQLQQCQVTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLNLLQVVSKEKPHLVRNILQSPDSSFEYIPPK----PKPFRIKEKCPEKSFAIEDLQYYSETSVAEEENEDSD----DHADEEWIPTKLVKVSKKNIQGCSCKGWCGNKQCGCRKQKSDCNGACSCDPTKCRN----RHHSQDNSDVIELNQDSENSFKLEDPTEVTSGLSFFNPVCTTPSSKILKEMCDADQVLLRQPDFASS-SDHLELKPIASETQENKAMGKKKKRALASNTSFFSGCSPIQEESH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33174-1", "uniprot_id": "KIF4_MOUSE", "id": "P33174-1", "name": "Chromosome-associated kinesin KIF4", "aln": "MKEEVKGIPVRVALRCRPLVSKEIKEGCQTCLS-FVPGEPQVVVGNDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKS-DFEFTLKVSYLEIYNEEILDLLCSSREKATQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLREGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQILLLQ----------AHGGTLPGDINVEPSEN--------LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRRHAACKVDLQKLVETLEDQELKENIEIICNLQQVIAQLSDEAAACMTATIDTAGEADTQVQSSP----DTSRSSDVFSTQHALRQAQMSKELIELNKALALKEALAKKMTQNDNQLQPIQFQYQDNIKNLESEVLSLQREKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLQEQSKLLKLKESTEHTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQSRG-----MESTAARMKNWLGNEIEVMVSTEEAKRHLNGLLEERKILAQDVAQLKEKRESGENPPLKLRRRTFSYDEIHGQDSGAEDSIAKQIESLETELELRSAQIADLQQKLLDAESEDRPKQRWESIATILEAKCAIKYLVGELVSSKILVSKLESSLNQSKASCIDVQKMLFEEQNHFAKIETELKEELVKVEQQHQEKVLYLLSQLQQSQMTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLTLLQVASKQKPHLTRNIFQSPDSSFEYIPPK----PKPCRIKEKCLEQSFAVEGLQYYSEPSVAEQDNEDSD----DHADEEWIPTKLVKVSKKSIQGCSCKGWCGNKQCGCRKQKSDCNVSCSCDPTKCRN----RHQNQDNSDAIELNQDSENSFKLEDPTEVTSGLSFFHPICATPSSKILKEMCDADQVQLKQPVFVSS-SDHPELKSIASESQENKAIGKKKKRALASNTSFFSGCSPIQEESH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLI2-1", "uniprot_id": "A0A8I6GLI2_RAT", "id": "A0A8I6GLI2-1", "name": "", "aln": "MKEEVKEIPVRVALRCRPLVPKEIGEGCQ---------------------------------EEVFNTAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYRANQEDEPTIGVIPRVIQLLFKEMEEKR-DSEFTLRVSYLEIYNEEILDLLCSSCEKASQIHIREDPKAGIKTVGLTEKTVSVASDMVSCLEQGNNARTVAATAMNSQSSRSHAIFTVFIRQRKKTDKSSSFHSKLCLVDLAGSERQKKTKAEGDRLREGININRGLLCLGNVISALGDGKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSSLEETLNTLRYADRARKIKNEPVINTDPQTAELTHLKHQVQQLRVLLLQ----------AHGGSLPGSIIAEPSES--------LQSLMEKNQSLGEENEKLSHALSEAAGQTAQMLERIILTEQANEQLNTKLQELSDHVACKVDLQKLTETLEDQELIEKIEIIRSLQQAVIHLSDENVVAT----ESAMELETQVAISP----KSRRSSDALTTQHALRQAQMSKELTELNKALAVKEALARKITFNGGQLQPIHCQYEVNIRSLESEVASLQKEKEQLLLDLQLAKKDANQAKLGEHRRKCLQELEAQIADLKKKLSEQSKLLKLKESTENTVSKLTLEIQMMKTQRVQLMRQMKEDAEKSRQWKQQKDKEVIQLREQDRKRRYELLKLERDFQKQSNVLRRKTEEAAAANKRLKDALQKQRDAADKRKETQNRG-----LEGTEARVKNWLSNEIEVMVSTEDVKHHLNDLLEERKILALDMAQLKENKEPGENPPLKLQKWTFASDEVCGHSSEPEDSITKQIRSLEAEMELRNAQIADLQQKLLDAESEDRPKRHWESIATVLEAKCALKYLVGEVVSSKLQVSELESNLKQSQASHSKTQKMLLEEQSHLVQVEAEWKAELSKAEQKHQEKELYLLSQLQQSQMAEQRLEVSVSGKEQQLLSTLQCQEDQFRKMQELCEQNQQLLQENEAIRQKLSLFQGTKDQKSHLPRDDLQSPDSSFNYIPPP----PKASRVRGKFLDQSMDIDDLNSYPEYSMSESEDGDGH-------DKEWKPRKLAKVSRKTFQGCSCKGWCRNKHCGCRKQGVDCCVACGCDPTKCRN----RQQEQESLGTVEWNQDSEVSFKLDDPTEVTPGLSFFNPVCATPNTKLLKEMCDMDQALWRTTDLAVS-LDLPDIKHRATESQENQATGKKKKRILACNSLFFSGCSPSKEEAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9XZ29-1", "uniprot_id": "Q9XZ29_DROME", "id": "Q9XZ29-1", "name": "", "aln": "-MSSEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNG--VLDDHVGVIPRAVHDIFTAIAEMQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIR-EVKNRIIMPGLTELVVTSAQQVTDHLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRFNLVDLAGSERCSKTLASGDRFKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAVGAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLD--SDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKRLQLLEQEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAAGSSNANAKTDSWVDRELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQQEKTS---------------------DPAEAAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQ---QRRLQASSLNEQRTTLDELRAQLLDAQ---------------QQEDAASKRLRLLQSQHEEQMLAQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQILEELLSSREALQQELDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNETVVLSDVSDDPDWVPSTSKSKRIQSDSRNVISPPEKQDANVTSLGNSSIQSLNSTSATEDGKRCKGCKCRTKCTTKRCGCLSGNNACSETCVCK-SNCRNPLNLKDHASQCGDGDGQKDETEDADKSDDDGDDEPQTSKENAVKFVTPEAPGKVVASPKQTLQEPKAAATP-----LMNSNVVEDINGPKLAKMSGLAFDTPKRKFF----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * **** **** .*: .**: :::*:..* . :* :::***.*:************:** *: . : :*:***.:: :*. : : : .*:: *::*:*:*:: **:... .. :.** : * * **** .* * : .. * :*. *:**:****. *********: : * .*.. *:: ********* .** *.***::**:***:***.*****.***..: ..::***:*************** *********** .: ***.******** :***:*::* **::**:. **. :*:*:: **. * *.: * * : * :* * *: ::* :.*.**.: * :: : :: * ::**.::::.:::.** : : : * *. :.:: ....:: . : : ::* . . :: . . . . : ::: :* ::: *: ::*. * :*: * .:: * .:*: : : ::: : :: .*: *:.:*: :*: *.. .***.*.*:* ** ** :*::*::** *::***:::. . .:.:*. ** ** .:*:*:* *: ::** **** ::**: **:.:*** : *::: : ..** .**:** *** **********::* .. :*:: :..* .. *: .*:..*:*:::* :.:: *: *:*:* :: . *:::: . :: : *** *:*:*.***:*****: :: :.: : *.: :: *:: . * *: :*. ..* :.::: . : *:: : : *: .:: * ** :: ::::: . : . .: . : :: : ::** ... ::*:* :: . .* : .. . *.**: : . . .: . :: .. : :. *.. . : . .. . * :**.*: * .*:*** . * * *. ::*** :.: .: . .:::* : * :* : . * :.: .. * :.. .*. . . . : . * :. .* . : . * ", "identical_positions": 328, "similar_positions": 415, "identity": "25.77%" }, { "cls_id": "homologset.agr.FB:FBgn0011638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38656-1", "uniprot_id": "LA_RAT", "id": "P38656-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKANLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVDTPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDFHFLFSNHG--EIKWIDFVRGAKEGIILFKEKAKDALEKARSANNG-NLLLRNKKVTWKVLEGHAEKDAMKKITDDQQESLNKWKSKGGHAARRFKGSHVFTAARRFKGRGKGNRPAYAGAPKGRGQFQGRRTRFDDDDHR--------RGPVKRGIDGRDREEPASKHKKRENGARDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32067-1", "uniprot_id": "LA_MOUSE", "id": "P32067-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVEIPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHG--EIKWVDFARGAKEGIILFKEKAKEALEKARNANNG-NLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRR--------RGPMKRGRDGRDREEPASKHKKRENGARDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05455-1", "uniprot_id": "LA_HUMAN", "id": "P05455-1", "name": "Lupus La protein", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLEDKGQVLNIQMRRTLHK-----AFKGSIFVVFDSIESAKKFVETPGQK-YKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHG--EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG-NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKG----------------RRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQB7-1", "uniprot_id": "A0AC58JQB7_DANRE", "id": "A0AC58JQB7-1", "name": "", "aln": "MQLHEARSPKPELVPVNVYDRSCVLCTICTQAMHMFSVLLKRNKITTELWPVSCCLTGGVIGVDGYTVIQRSTNEVMFVVILAKMADNQEMSPLEKKVAEQIEYYFGDHNLPRDKFLKEQLQLD-DGWVPLETMLKFNRLKSLTSEESVIVESLLKSKTGLLEISEDKTKIRRDPNKPLPENNEEYRDALKHKSIYMKGFPLETTLD--------DVKEWLADKGTFENIYLRKGPQK-----TFKGSIFAVLETEEAAKAFVERDDIKNFKGNEMIVMMKDAYFTKKIAERKQNRVESKAKAKCDKEEKQKQAEEEEMKSLNEQRGCLLKFSGELG-QTSREDFHSVFSDHA--QIKWIDFTRGAKEGTILFHSNAKEALQKVREALNGEDPKVKEQAVQWEILEGDVEMETLKKIIEDQQESINKRKGGRG----------------GFRGRGRGRGGRRDRGGREHTQFKGKKTKFDSDEEGDEESASTKKRPLESNRQ--DNGEPVSKQAKSENGS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40796-1", "uniprot_id": "LA_DROME", "id": "P40796-1", "name": "La protein homolog", "aln": "--------------------------------------------MAEVAETPSVEAQEEVAQPAEAQVLEAKNGDAKKDPAPAAEEAAGGFTKQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGFPLDSQIS--------ELLDFAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIV-YKERELLRKWQVDYLKEKQEEYAQKNEKRKNKKEAKPEP-----------AFELPKNAIVVFEGAPE-TSSREEIREAFEKIKDFEVAYIEFAKGETKGSVRLTEADAAEKYIAKVEEGK-LKFKDEVSLSLRKATEEEEKEFIDKAIEFMKKRRDFTRNKGK----------------RFNRKRHGGNDHKHGG--------GKKARGD-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33399-1", "uniprot_id": "LHP1_YEAST", "id": "P33399-1", "name": "La protein homolog", "aln": "-----------------------------------------------------------------MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKN-DGWVPISTIATFNRMKKYRP-VDKVIEALRSSE--ILEVSADGENVKRRVPLDLTAARN-ARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQVRLRRDHRNK----KFNGTVLVEFKTIPECEAFLKSYSND-DESNEILSYEGKKLSVLTKKQFDLQREASKSKN----------------------------FSGRSR-----------------------SFNGHKKKNLPKFPKNKKKNGK-------------------------EESKEDSSAIADDDEEHKE-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*:*:**.: *: *:**: : :****:. : .*:*: . . :: :* .*: ::*:* * .::* :. : : :.:: .** : :: : . . . :: :*: : *:*::: :.: .: *:. : ::: . : .. * : *.* .* .:. : . . . : . : :: : ", "identical_positions": 30, "similar_positions": 86, "identity": "5.74%" }, { "cls_id": "homologset.agr.FB:FBgn0011640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64LC9-1", "uniprot_id": "RBM4B_RAT", "id": "Q64LC9-1", "name": "RNA-binding protein 4B", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--VDRTG--RVADFTEQYN-----------------------------EQYGAVR-----TP---------YTMGYGESMYY--------------NDAYG--------ALD-YYKRYR-------------VRSYEAVAAAAAASAYNYAEQTMSHLPQVQSSAVPSHLNSTSVDPYDRHLLQNSG----SAATSAAMAAAAS--SSYYGRDRSPLRRNAAVLPTVGEGYGYGPESEMSQASAATRNSLYDMARYEREQYVDRARYSAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE92-1", "uniprot_id": "RBM4B_MOUSE", "id": "Q8VE92-1", "name": "RNA-binding protein 4B", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--VDRTG--RVADFTEQYN-----------------------------EQYGAVR-----TP---------YTMGYGESMYY--------------NDAYG--------ALD-YYKRYR-------------VRSYEAVAAAAAASAYNYAEQTMSHLPQVQSSAVPSHLNSTSVDPYDRHLLQNSG----SAATSAAMAAAAS--SSYYGRDRSPLRRNAAVLPAVGEGYGYGPESEMSQASAATRNSLYDMARYEREQYVDRTRYSAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ04-1", "uniprot_id": "RBM4B_HUMAN", "id": "Q9BQ04-1", "name": "RNA-binding protein 4B", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--VDRTG--RVADFTEQYN-----------------------------EQYGAVR-----TP---------YTMGYGESMYY--------------NDAYG--------ALD-YYKRYR-------------VRSYEAVAAAAAASAYNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSG----AAATSAAMAAAAATTSSYYGRDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRARYSAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BWF3-1", "uniprot_id": "RBM4_HUMAN", "id": "Q9BWF3-1", "name": "RNA-binding protein 4", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--IDRSG--RVADLTEQYN-----------------------------EQYGAVR-----TP---------YTMSYGDSLYY--------------NNAYG--------ALDAYYKRCRA------------ARSYEAVAAAAASVY-NYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAASTSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRARYSAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C7Q4-1", "uniprot_id": "RBM4_MOUSE", "id": "Q8C7Q4-1", "name": "RNA-binding protein 4", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--IDRSG--RVADLTEQYN-----------------------------EQYGAVR-----TP---------YTMSYGDSLYY--------------NNTYG--------ALDAYYKRCRA------------ARSYEAVAAAAASAYSNYAEQTLSQLPQVQNTAMASHLTSTSLDPYNRHLLPPSG----AAAAAAAAAACTAASTSYYGRDRSPLRRATGPVLTVGEGYGYGHDSELSQASAAARNSLYDMARYEREQYADRARYSAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ97-1", "uniprot_id": "RBM41_DANRE", "id": "Q6IQ97-1", "name": "RNA-binding protein 4.1", "aln": "-----MVKIFVGNLSPNTTAEEIRSLFSQYGKISECDIVKNFGFVHMDSKSEADEAIQNLHHYMLNGMAMNVEMSKGK---PKTSTKLHVGNISSSCTNQELRAKFEEYGPVVECDIVKDYAFVHMERVEDAMEAISGLDNTAFQGKLMSVKLSTSRLRTAPGMGERTGCYRCGQEGHWSKECP--LDQNGSYREGPSSEGFGPVRFDSGGDRGRGFHRGFSGEPAYAGSFAPSHGFTRGAGYAVPGYGRGAGFESAMGYGMPAGYGVGADNSMAPVYGSEAAYGTSGMAYPGALPAYPIRRPPYEERDPYGVVDFYEKYRARPYGGSYFEDRRAVQPPVPPPPTSTPVVRERLPSNLVDPYERHPLPPPP----------------APTSSYYVRERSPVRR----APHEAEGYAYE-RSRLSPISVLPRTAAYDVP---RDPYAERARYAY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94901-1", "uniprot_id": "LARK_DROME", "id": "Q94901-1", "name": "RNA-binding protein lark", "aln": "MPGAGTFKLFIGNLDEKTQATELRALFEKYGTVVECDVVKNYGFVHMETEQQGRDAIQNLNGYTLNEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAG-------------------------------------------------------GYRDRMYG--------------RDPYP------PPPPPPPFLRDRIMDG---------FRDYDYYDRRFEDSRDLYERRYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCS--------------VSRGYDTMFSRRSPPPPR----SSNGMSRYGSPTPHGYEDFSRDAFDERMISSRGMRGPSPPGRRYAPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:*:*** :: *:*:**.:**.: ***::**:****:: : . :**:**: * *: . ::** :*.: ..:**:.***:: . *:* *::**.*:*****::*.***:: . *. :** *:. .:*: : *::****:*. ****: *****:.******** . * * . . .* . .* . * ..* : . .: . : * * : : * .* * . *. . * . . * **: ", "identical_positions": 93, "similar_positions": 86, "identity": "20.48%" }, { "cls_id": "homologset.agr.FB:FBgn0011648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1V3-1", "uniprot_id": "SMAD5_RAT", "id": "Q9R1V3-1", "name": "SMAD family member 5", "aln": "-------------MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRN-LSHNEPHMPQNATFPDSFHQPNS-TPFPLSPNSP---YPPSPASS-----TYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTS--NNMIPQIMPSIS-SRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPANNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLA----QSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99717-1", "uniprot_id": "SMAD5_HUMAN", "id": "Q99717-1", "name": "SMAD family member 5", "aln": "-------------MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRN-LSHNEPHMPQNATFPDSFHQPNN-TPFPLSPNSP---YPPSPASS-----TYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTS--NNMIPQIMPSIS-SRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLA----QSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97454-1", "uniprot_id": "SMAD5_MOUSE", "id": "P97454-1", "name": "SMAD family member 5", "aln": "-------------MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRN-LSHNEPHMPQNATFPDSFHQPNN-APFPLSPNSP---YPPSPASS-----TYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMAPDNSQPMDTS--SNMIPQTMPSIS-SRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLA----QSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W7E7-1", "uniprot_id": "SMAD5_DANRE", "id": "Q9W7E7-1", "name": "SMAD family member 5", "aln": "-------------MTSMSSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEDLEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEVCEYPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRN-LSHNEPHMPLNATFPESFQQHSGGSSFPISPNSP---YPPSPASSG----TYPNSPAS-SGPSSPFQLPADTPPPAYMPPDEQMGQDGSQSMETG--SSLAPQNMP----RGDVQPVEYQEPSHWCSIVYYELNNRVGEAYHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDTSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLA----QSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEVHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q15797-1", "uniprot_id": "SMAD1_HUMAN", "id": "Q15797-1", "name": "SMAD family member 1", "aln": "--------------MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRN-LGQNEPHMPLNATFPDSFQQPNS-HPFPHSPNS---SYPNSPGS---SSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDT---NMMAPPLPSEIN-RGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLA----QSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70340-1", "uniprot_id": "SMAD1_MOUSE", "id": "P70340-1", "name": "SMAD family member 1", "aln": "--------------MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRN-LGQNEPHMPLNATFPDSFQQPNS-HPFPHSPNS---SYPNSPGG---SSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMAQDGSQPMDT---NMMAPPLPAEIS-RGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLA----QSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97588-1", "uniprot_id": "SMAD1_RAT", "id": "P97588-1", "name": "SMAD family member 1", "aln": "--------------MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRN-LGQNEPHMPLNATFPDSFQQPHS-HPFAQYPNS---SYPNSPGS---SSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMAQDGSQPMDTNMTNMTAPTLPAEIN-RGDVQAVAYEEPKHWCSIVYYELNNRVGERFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLA----QSVNHGFETEYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9I8V2-1", "uniprot_id": "SMAD1_DANRE", "id": "Q9I8V2-1", "name": "SMAD family member 1", "aln": "--------------MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELERALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALECCEFPFGSKQKDVCINPYHYKRVDSPVLPPVLVPRNSEFNAKLSMLPRFRNPLHQTEPPMPQNATFPDSFPQQPA-NALPFTPNSPTNSYPSSPNSGTGSTATFPHSPSS-SDPGSPFQMP-ETPPPAYMPPEEPMTQDCPQPMDT---NLLAPNLPLEISNRTDVHPVAYQEPKHWCSIVYYELNNRVGEAFLASSTSVLVDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSRCSLKIFNNQEFAELLA----QSVNHGFEAVYELTKMCTIRMSFVKGWGAKYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O54835-1", "uniprot_id": "SMAD9_RAT", "id": "O54835-1", "name": "SMAD family member 9", "aln": "----------MHPSTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQSLG-PAPPSSPGHV---FPQSPCPT-----SYPQSPGSPSESDSPYQHS-------------------------------------------DFRPVCYEEPLHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIW5-1", "uniprot_id": "SMAD9_MOUSE", "id": "Q9JIW5-1", "name": "SMAD family member 9", "aln": "----------MHPSTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQSLC-PAPPSSPGHV---FPQSPCPT-----SYPHSPGSPSESDSPYQHS-------------------------------------------DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLA----QSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15198-1", "uniprot_id": "SMAD9_HUMAN", "id": "O15198-1", "name": "SMAD family member 9", "aln": "----------MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC-SALPPSPSHA---FSQSPCTA-----SYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSG-QPVDAT----ADRHVVLSIP-NGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLA----QSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QXZ9-1", "uniprot_id": "F1QXZ9_DANRE", "id": "F1QXZ9-1", "name": "Mothers against decapentaplegic homolog", "aln": "----------MHSSTSITSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMEELEKALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALDCCEFPFGSKQKEICINPYHYRRVETPVLPPVLVPRHSEFNPQHSLLAKFRNASLHNEPLMPQNATFPDSFPAMPC-SSFSSSPSSS---LNPSPAAH-----SFPNSPSSATEPGSPYQITAETPPPPYSMMESSPSEDV-KPAESS----ENK-LILTAP-QRDLRPVCYEEPEYWCSVAYYELNNRVGETFHASARSILVDGFTDPSNNKNRFCLGLLSNVNRNSTIEHTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYQHGFHPTTVCKIPSGCSLKIFNNQLFAQLLS----QSVNHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42003-1", "uniprot_id": "MAD_DROME", "id": "P42003-1", "name": "Protein mothers against dpp", "aln": "MDTDDVESNTSSAMSTLGSLFSFTSPAVKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRVESPVLPPVLVPRHSEFAPGHSML-QFNH---VAEPSMPHNVSYSNSGFNSHSLSTSNTSVGSP------SSVN---------------SNPNSPYDSLAGTPPPAYSPSEDGNSNN---PNDGG--QLLDAQMG-------DVAQVSYSEPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEFAQLLS----QSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNAISSVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***********:*******************:*******:***:::**:***.*****:*****************************************.*: *::**.:***::*******:**::**********:.*: . *:* :*. ** ** *.::.:* . . *. : . **:: *. * *.** .*.*:.***** **** : .. *:::****:*:** .* *** ***********:************** *******:**::*********::*****:******. ****:**** **:**: ***::***. *******************:**************:******************* *.*****", "identical_positions": 288, "similar_positions": 72, "identity": "58.06%" }, { "cls_id": "homologset.agr.FB:FBgn0011656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJY4-1", "uniprot_id": "MEF2C_RAT", "id": "A0A096MJY4-1", "name": "Myocyte-specific enhancer factor 2C", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------VPPPNFEMPVTIPVSSHNSLVYSNPVSSLGNPNLLP---LAHPSLQ------------RNSMSPGVTHRPPSAGNTGGLMGG---DLTSGAGTSAG---------NGYGNPRNSPGLLVSPG--NLNKNIQAKSPP----PMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVD---------------------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTE-------------YSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPP---------------------------SALSQLGACTSTHLSQSS-------NLSLPSTQSLNIKSEPVSPPRDRTTT--PSRYP-----QHT---------------RHEAGRSPVDSLSS-CSSSYDGSDREDHRNEFHSPIGLTRPSP---DERESPSVKRMRLSEG-WAT------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFN5-1", "uniprot_id": "MEF2C_MOUSE", "id": "Q8CFN5-1", "name": "Myocyte-specific enhancer factor 2C", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------VPPPSFEMPVTIPVSSHNSLVYSNPVSTLGNPNLLP---LAHPSLQ------------RNSMSPGVTHRPPSAGNTGGLMGG---DLTSGAGTSAG---------NGYGNPRNSPGLLVSPG--NLNKNIQAKSPP----PMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVD---------------------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTE-------------YSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPP---------------------------SALSQLGACTSTHLSQSS-------NLSLPSTQSLSIKSEPVSPPRDRTTT--PSRYP-----QHTT--------------RHEAGRSPVDSLSS-CSSSYDGSDREDHRNEFHSPIGLTRPSP---DERESPSVKRMRLSEG-WAT------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06413-1", "uniprot_id": "MEF2C_HUMAN", "id": "Q06413-1", "name": "Myocyte-specific enhancer factor 2C", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------VPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLP---LAHPSLQ------------RNSMSPGVTHRPPSAGNTGGLMGG---DLTSGAGTSAG---------NGYGNPRNSPGLLVSPG--NLNKNMQAKSPP----PMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVD---------------------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTE-------------YSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPP---------------------------SALSQLGACTSTHLSQSS-------NLSLPSTQSLNIKSEPVSPPRDRTTT--PSRYP-----QHT---------------RHEAGRSPVDSLSS-CSSSYDGSDREDHRNEFHSPIGLTRPSP---DERESPSVKRMRLSEG-WAT------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3N7-1", "uniprot_id": "A0A8M3B3N7_DANRE", "id": "A0A8M3B3N7-1", "name": "", "aln": "MGRKKIQIARIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDIDAEDS-GHSPESEDKYRKINEDIDL-MISRQRLCA----------------------------IPQSNYDMPVSIPVSNPNSLIYGHPGASLGNPNLLP---LTHPSLQ------------RNSMSPGVTHRPPSAGNTGGLMAA---DLGSGAGTSTG---------NGYGNHRNSPGLLVSPG--NMSKNLQAKSPP----SMNMSLS-RKPDLRVLIPPGAKNTMPSISEDVD---------------------MLLNQRISSSQSAQSLSTPVVSVATPTLPGEVMGGYPSAINTSYGTE-------------YSLSSGDLSSLSAFNSSASLHLGSMTGWP----QNMQH---------------------------SGLGHLGNCSSAQLCQSS-------ALSLPSNQNLHIKSEPVSPPRDRASG-TPGLYG-VP--QQTP-------------LRQDSGRSPVDSLSS-CGSSYDGSDRDEHRANFHSPVGLMRAAE---NERQSPSVKRMRLSEAGWAS------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B2S1-1", "uniprot_id": "A0A8M3B2S1_DANRE", "id": "A0A8M3B2S1-1", "name": "", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCDSPDPDADDSVGHSPESKDKYREINDDIDLHMISRQRICA----------------------------VPSSTYDM--TIPVNN---QIYP------GNHNLLP---LAHHGLQ------------RNSMSPGVTHRPPSAG---GLMGT---DLSTGAGTSAGKDGIPTYYRNGYGNHRNSPGLLVSSG--GMNKSMQAKSPP----PVNLGMNSRKPDLRVLIPPGAKNNMPSISEDVD---------------------LLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTSYGTE-------------YSLSSADLSSISGFNSANTLHLGSMSGWQQHQIQNMQH---------------------------SALSQLGNCSSSHLCQGS-------NLSLPSTQSLHIKSEPVSPPRDRSSSTTPGGYGQLPSHQQHQG--------PTSQGRQDSGRSPADSLSS-CGSSHEGSDRDEHRPDFHSPLGLGRPGL---DDQDSPSIKRIRLSEG-WAT------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02078-1", "uniprot_id": "MEF2A_HUMAN", "id": "Q02078-1", "name": "Myocyte-specific enhancer factor 2A", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVEALN--------------------------------------------KKEHRGCDSPDP--DTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPG----------------------------LPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQ----TTL-HRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVG--------NGFVNSRASPNLIGATGANSLGKVMPTKSPPP-PGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEE-L-------------------ELNTQRISSSQATQPLATPVVSVTTPSLPPQGL--VYSAMPTAYNTD-------------YSLTSADLSALQGFNSPGMLSLGQVSAWQQ---HHLGQ---------------------------AALSSL--VAGGQLSQGS-------NLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPN--TEDRESPSVKRMRMDA--WVT------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2MJT0-1", "uniprot_id": "MEF2A_RAT", "id": "Q2MJT0-1", "name": "Myocyte-specific enhancer factor 2A", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVEALN--------------------------------------------KKEHRGCDSPDP--DTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPG----------------------------LPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLAESSMLSPPP----ATL-HRNVSPGAPQRPPSTGSAGGMLSTTDLTVPNGAGNGPVG--------NGFVDSRASPNLIGNTGANSVGKVMPTKSPPP-PGGGSVGMNSRKPDLRVVIPPSSKGMMPPLN----------------------------AQRISSSQATQPLATPVVSVTTPSLPPQGL--VYSAMPTAYNTD-------------YSLTSADLSALQGFTSPGMLSLGQASAWQQ---HHLGQ---------------------------AALSSL--VAGGQLSQGS-------NLSINTNQNINIKTEPISPPRDRMTPSGFQQQQQQQPQQQPPP----QPPQPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPN--AEDRESPSVKRMRMDT--WVT------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60929-1", "uniprot_id": "MEF2A_MOUSE", "id": "Q60929-1", "name": "Myocyte-specific enhancer factor 2A", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVETLR--------------------------------------------KKGLNGCESPDA--DDYFEHSPLSEDRFSKLNEDSDFIFK--RGPPG----------------------------LPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLADSSMLSPPP----ATL-HRNVSPGAPQRPPSTGSASGMLSTTDLTVPNGAGNSPVG--------NGFVNSRASPNLIGNTGANSLGKVMPTKSPPP-PGGGSLGMNSRKPDLRVVIPPSSKGMMPPLSEEEE-L-------------------ELNAQRISSSQATQPLATPVVSVTTPSLPPQGL--VYSAMPTAYNTD-------------YSLTSADLSALQGFTSPGMLSLGQASAWQQ---HHLGQ---------------------------AALSSL--VAGGQLSQGS-------NLSINTNQNINIKSEPISPPRDRMTPSGFQQQQQQ-PQQQPPP------QPPQPQPRQEMGRSPVDSLSS-SSSSYDGSDREDPRGDFHSPIVLGRPPN--TEDRESPSVKRMRMDT--WVT------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T6Z3-1", "uniprot_id": "A0AB32T6Z3_DANRE", "id": "A0AB32T6Z3-1", "name": "", "aln": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNSDIVEKLRNKGHNDCPSPDPDDCFGHSPLMDDRFGKLNEESDLMYKRCGALNKKEHRGCDSPDP--DASYVLTPHTEEKYKKINEEFDNMMRNHKIPTA----------------------------LPPQNFSMHVAVPVTNPNAMSY-NPGASLSSQSLSAAASLSDGAMLSPPQ----GSM-HRSVVP--PQRPPSTG-------------------STAG--------NGFVNPRGSPGLLGTPSGNGLGKVMPAKSPPP-PGG-NMGIGSRKPDLRVVIPPSSKGMMPPLQSEEEEM-------------------ELNTQRISSSQSTQPLATPVVSVTTPSLAPQGL--VYSGMPTAYNSE-------------YSLSSAELSSLQGFGSPG-LSIGSVSAWQQ---HQLGQ---------------------------AALSSL--VGGGHLPQGS-------NLSINTSQNVNIKSEPISPPRERVTPSGFPPQQQQ-----------------PPSGRPDMGRSPVDSLSS-SCSSYDGSDREDHRPDFHSPLGLGRPPAGGADERESPSVKRMRMDT--WVT------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q63943-1", "uniprot_id": "MEF2D_MOUSE", "id": "Q63943-1", "name": "Myocyte-specific enhancer factor 2D", "aln": "MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNADIIETLR--------------------------------------------KKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDG--LFRRYGSS----------------------------VPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSS-LTDPRLLSPQQ----PALQRNSVSPGLPQRPASAG---AMLGG-DLNSANGACPSPVG--------NGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHLTEDHL-D-------------------LNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP--FSSMPTAYNTD-------------YQLPSAELSSLPAFSSPAGLALGNVTAWQQPQPPQQPQPPQPPQ---SQPQPPQPQ----PQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVF------------------------PAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP--EPEAEGSAVKRMRLDT--WTLK-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89038-1", "uniprot_id": "MEF2D_RAT", "id": "O89038-1", "name": "Myocyte-specific enhancer factor 2D", "aln": "MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNADIIETLR--------------------------------------------KKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDG--LFRRYGSS----------------------------VPAPNFAMPVTVPVSNQSSMQFSNPSSSLVTPSLVTSS-LTDPRLLSPQQ----PALQRNSVSPGLPQRPASAG---AMLGR-DLNSANGACPNPVG--------NGYVSARASPGLLPVANGNGLNKVIPAKSPPPPTHNTQLGAPSRKPDLRVITSQGGKGLMHHL---------------------------NNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP--FSSMPTAYNTD-------------YQLPSAELSSLPAFSSPAGLALGNVTAWQQPQQPQQPQPPQPPQ---SQPQPPQPQ----PQQPPQQQPHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVF------------------------PAARPEPGEGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP--EPEAEGSAVKRMRLDT--WTLK-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14814-1", "uniprot_id": "MEF2D_HUMAN", "id": "Q14814-1", "name": "Myocyte-specific enhancer factor 2D", "aln": "MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKY-------------TEYNEPHESRTNADIIETLR--------------------------------------------KKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDG--LFRRYGST----------------------------VPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSS-LTDPRLLSPQQ----PALQRNSVSPGLPQRPASAG---AMLGG-DLNSANGACPSPVG--------NGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHL-D-------------------LNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP--FSSMPTAYNTD-------------YQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVF------------------------PAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAP--EPEAEGSAVKRMRLDT--WTLK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55087-1", "uniprot_id": "MEF2B_MOUSE", "id": "O55087-1", "name": "Myocyte-specific enhancer factor 2B", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKY-------------TEYSEPHESRTNADILQTLK--------------------------------------------RRGV-GLDGPELDMEEGPEGPG---EKLLR---------TLGGDRGS----------------------------ASPRPRIYPVAPAMSVSE----------LSYRVPPATPGCDPGGL---------------GEVPSVHSRPAYFR------------------------------PPGLGHPIFSPSHLAS------------KTPPP----LYLATDGRRPDL----PPGLVGARGGLG------------------------------------TSRSLYSGLQ---SPGAPGPA-----------LGS--------------FAFLPS----------------------------------------------------------GSTDCSPGDAAQGPLQPSP---------WPPTRDAV----DPARPVARSLCKEGPPSRG------------------------ASPPTPPVSIKS--ERLSPVTGTSGDFPRSFPYPLLLARPLA---EP-LRPSASLHRLTPDSWPR------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EZT3-1", "uniprot_id": "F7EZT3_RAT", "id": "F7EZT3-1", "name": "", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKY-------------TEYSEPHESRTNADILQTLK--------------------------------------------RRGV-GLDGPELDMEEGPEGPG---EKLLR---------TLGGDRGL----------------------------VSPPPRIYPVAPAMSVSE----------LSYRVPPATSGCDPGGL---------------GEAPSVHSRSPHFR------------------------------PPGLGHPIFSPSHLAG------------KTPPP----LYLATDGRRPDL----PPGLVGARGGLG------------------------------------TSRSLYSGLQ---SPGAPGPA-----------LGS--------------FAFLPP----------------------------------------------------------GSADCSPGDAAQVPLQPSP---------WPPTRDAV----DPAGPAARSLCEEGPPSRE------------------------ASPPTPPVSIKS--ERLSPVTGTSGDFPRSFPYPLLLARPLA---EP-LRP-ASLRRLTPDSWPR------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02080-1", "uniprot_id": "MEF2B_HUMAN", "id": "Q02080-1", "name": "Myocyte-specific enhancer factor 2B", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYASTDMDRVLLKY-------------TEYSEPHESRTNTDILETLK--------------------------------------------RRGI-GLDGPELEPDEGPEEPG---EKFRR---------LAGEGGDP----------------------------ALPRPRLYPAAPAMPSPD----------VVYGALPP-PGCDPSGL---------------GEALPAQSRPSPFRPAAPK---------------AG--------PPGLVHPLFSPSHLTS------------KTPPP----LYLPTEGRRSDL----PGGLAGPRGGLN------------------------------------TSRSLYSGLQNPCSTATPGPP-----------LGS--------------FPFLPG----------------------------------------------------------GPP---VGAEAWARRVPQP---------AAPPRRPP----QSASSLSASLRPPGAPATF------------------------LRPSPIPCSSPGPWQSLCGLGPPCAGCPWPTAGPGRRSPGGT---SPERSPGTARARGDPTSLQASSEKTQQ-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IEL7-1", "uniprot_id": "A0AC58IEL7_DANRE", "id": "A0AC58IEL7-1", "name": "", "aln": "MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNRLFQYASTDMDKVLLKY-------------TEYSEPHESRTNTDILETLR--------------------------------------------RKGL-GLESSEIDPEDGVTMGA---EKYHDG-------MDLSLARQR----------------------------YYAPSLLHSEVINTSAENGYINSSNPNLGAHRTPSYKPLCTRPGS---------------TGTVSANSHPALMGPHADTNLY----------NDIG--------DTGLGYSMFPHGSLSRAL--------EMKTPPP----LNMSSDGRRVEA----HAGLCGTRSSLANAVR------------------------------ESTKRALYQSMHAGGHMMAMGKTGL---------LGHG-------------LNYSPSEYSHPGYTVGFQRSSMNTWQPLTHQDAHQSMI--------------------------SPGMASGGSCSYPSQSSSP---------SSPSHPSLNLSIKSERTSPVHMISPTPPSHH------------------------MLQHSPIAEPKS---SSCPPSDEYADLQREEAQKSSFSGQQQ---GPNRDPPETKSSPNPKQQDISNGWIR------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40791-1", "uniprot_id": "MEF2_DROME", "id": "P40791-1", "name": "Myocyte-specific enhancer factor 2", "aln": "MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKY-------------TEYNEPHESLTNKNIIEKEN--------------------------------------------KNGVMSPDSPEA--ETDYTLTPRTEAKYNKIDEEFQNMMQRNQMAIGGAGAPRQ---------------------LPNSSYTLPVSVPVPGSYGDNLLQASPQMSHTNISPRPSSSETDSGGMSL----IIYPSGSMLEMSNGYPHSHSPLVGSPSP---------GPSPGIAHHLSIKQQSPGSQNGRASNLRVVIPPTIAPIPPNMSAPDDVGYADQRQSQTSLNTPVVTLQTPIPALTSYSFGAQDFSSS---------------GVMNSADIMSLNTWHQGLVPHSSLSHLAVSNSTPPPATSPVSIKVKAE-------------PQSPPRDLSASGHQQNSNGSTGSGGSSSSTSSNASGGAGGGGAVSAANVITHLNNVSVLAGGPSGQGGGGGGGGSNGNVEQATN-------LSVLSHAQQHHLGMPNSRPSSTGHITPTPGHDKYEG----------------YPYRALMGHNPRWNLNFAGAPSSDQDVRLAAVAVQQQQQQPHQQQQ--LGDYDAPNHKRPRISGG-WGT------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12224-1", "uniprot_id": "RLM1_YEAST", "id": "Q12224-1", "name": "Transcription factor RLM1", "aln": "MGRRKIEIQRISDDRNRAVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEFSSVDTNDLIYHYQNDKNLLHEVKDPSDYGDFHKSASVNINQDLLRSSMSNK------------------------------------PSKSNVKGMNQSENDDDENNDEDDDDHGNFERNSNMHSNKKASDKNIPSAHMKLLSPTALISKMDGSEQNKRHPENALPPLQHLKRLKPDPLQISRTPQQQQQQNISRPYHSSMYNLNQPSSSSSSPSTMDFPKLPSFQNSSFNGRPPPISISPNKFSKPFTNASSRTPKQEHKINNSGSNNNDNSNYTQSPSNSLEDSIQQTVKARRKLSARP-VLRVRIPNNNFSSNSAIPSEPSSASSTSANGNSMGSSQIMKENKTSRSSKISPLSASASGPLTLQKGNNGRMVIKLPNANAPNGSNNGNGSNNNNHPYPFGSGSSPLFSATQPYIATPLQPSNIPGGPFQQNTSFLAQRQTQQYQQMSFKKQSQ----------------TVPLTTTLTGRPPSTFSGPETSNGPPTGSLPSKFVHDLMSNSPNVSSISMFPDWSMGPNSAKPGNTNNPGTFPPVQTAVNNGNSSNISSTNNTNNNNNNNNNNSSNNNSNNGNDNNSNNSNNSYYSNNEDAPVNGAAISEHTTDGDSNNQSNSSTYDAAATAYNGNTGLTPYINTAQTPLGTKFFNFSTDISGEKNSSKI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38128-1", "uniprot_id": "SMP1_YEAST", "id": "P38128-1", "name": "Transcription factor SMP1", "aln": "MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVDMSNLLNVH------------QNNTDLPHNIIEPSDYGDYVK--------------------------------------------KPRVVLNERKRRRRRATVLQPASHSGSCTVSSQDSSSVQNNGNLSAP---------------------------LASNDAGNAGVSTPLVHCHGAISRSGSNHSDCARNSADYQMLQGGLNSGGS----------FHANDYKESVDQQHVANEAIHR------------------------NFMNKRIRPDTHLLLSESNHSNYHNFYPSPY----ENLPKPSLPASLVGNIPSFQSQFVQVIPANSN----------------------PMGKGFNGTGDSESFEAKQKIHPTVAISNTLEG---------------------------PAPVQAMVHHLHQLNSNRGKLSGKPYLKLN----------------------------------IPKATNDACQRSPAMYSG-----------TASPKTDVQATPNQMLASNMSSPLSRSKFLG----------------------FKNNDMDDLYHNGRCGSTYVNNKTFFLKPPIGRPPKFPKSPSSSIVVFPSSVASSTLKSTSSTNSPD----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**:* * *:*** *** *** *::***:******: :**:**:. : :::::* * . :: : .: . *: : . : : . . .. . . . . ", "identical_positions": 34, "similar_positions": 37, "identity": "4.66%" }, { "cls_id": "homologset.agr.FB:FBgn0011659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97679-1", "uniprot_id": "MLH1_RAT", "id": "P97679-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMTENCLDAKSTNIQVIVREGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLAMISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRKKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESAALKKAIEAVYAAYLPKNTHPFLYLILEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEAVKSTTGIASSSTSGSGDKVHAYQMVRTDSRDQKLDAFMQPVSRRLPSQPQD--PVPGNRTEGSPEKAMQKDQEISELPAPMEAAADSASLERESVIGASEVVAPQRHPSSPGSSRKRHPEDSDVEMMENDSRKEMTAACYPRRRIINLTSVLSLQEEINDRGHETLREMLRNHTFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLPEPAPLFDFAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAKMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEE-ECFESLSKECAVFYS--IRKQYILEESALSGQQSDMPGSPSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLCKVFERC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK91-1", "uniprot_id": "MLH1_MOUSE", "id": "Q9JK91-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTNIQVVVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRRKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESAALRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILQRVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEAARPTTGVASSSTSGSGDKVYAYQMVRTDSREQKLDAFLQPVSSLGPSQPQDPAPVRGARTEGSPERATREDEEMLALPAPAEAAAESENLERESLMETSDAAQKAAPTSSPGSSRKRHREDSDVEMVENASGKEMTAACYPRRRIINLTSVLSLQEEISERCHETLREMLRNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYS--IRKQYILEESTLSGQQSDMPGSTSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLYKVFERC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40692-1", "uniprot_id": "MLH1_HUMAN", "id": "P40692-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQA--IVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSS--NPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGN--------LIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYS--IRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AAI6-1", "uniprot_id": "A0AB13AAI6_DANRE", "id": "A0AB13AAI6-1", "name": "DNA mismatch repair protein MLH1", "aln": "-----MAGVIRRLDETVVNRIAAGEIIQRPANAIKEMMENCLDAKSTNIQITVKEGGLKLILIQDNGTGIRKDDMEIVCERFTTSKLQSFEDLSSIATYGFRGEALASISHVAHVTITTKTADAKCAYRANYCDGKLKSPPKPCAGNQGTLISVEDLFYNVSTRRKALKSPSEEYSRIVEVVSRYAIHNSGKSFSVKKQGEMVADVKTLPNASVLDNIRVVFGVAVSRELIEVECE--DQKFAFKVKGYISNANYSVKKCIL-ILFINHRLVESSALKKAIETVYTAYLPKNTHPFLYLSLEIAPQNIDVNVHPTKHEVHFLHEDSIIESIQKHIESKLLGSNSSRTYFTQTLLPGLS------------ASASVAKASSSSADSQERVYAHQMVRTDSKAQKLDAFLQPSASSSSTAAQR-------KTEKTSSTSTAVQDLVELDDAELLTAADVEPCGGK------DPQTDAQPPGDEAPPRKRP----HVEEVKED----LTAASLPRRRIVKLTSIKELRDQIELQTHKGLQELLQNHSFVGSVSPQW--TLVQHQTKLYLLNTTKLSQELFYQILVYDFGNFGVLRLSNPAPLYDLAMLALDSEESGWTEEDGPKEGLAQYIVDFLKQKAEMLEEYFSLEIDAEGN--------LTGLPMLLDNYTPAMEGLPMFILRLATEVNWDKEKECFREFSVECSHFYS--IRKSYTLEADADEPQDAEMS------WQWKVEHVLFKALRSLFSPAKHLSEDGSVLQIASLPDLYKVFERC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7C1-1", "uniprot_id": "A1Z7C1_DROME", "id": "A1Z7C1-1", "name": "", "aln": "MAEYLQPGVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNGTGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKTAKEKCGYKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVLARYAVHNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAAISKELLEFSHR--DEVYKFEAECLITQVNYSAKKCQM-LLFINQRLVESTALRTSVDSIYATYLPRGHHPFVYMSLTLPPQNLDVNVHPTKHEVHFLYQEEIVDSIKQQVEARLLGSNATRTFYKQLRLPGAP-----------------DLDETQLADKTQRIYPKEMVRTDSTEQKLDKFLAPLVKSDSGVSSS-----------SSQEASRLPEESFRVTAAKKS------------------------------------------------------------REVRLSSVLDMRKRVERQCSVQLRSTLKNLVYVGCVDERR--ALFQHETRLYMCNTRSFSEELFYQRMIYEFQNCSEITISPPLPLKELLILSLESEAAGWTPEDGDKAELADGAADILLKKAPIMREYFGLRISEDGM--------LESLPSLLHQHRPCVAHLPVYLLRLATEVDWEQETRCFETFCRETARFY-----AQLDWREGATAGFS-----------RWTMEHVLFPAFKKYLLPPPRIKD--QIYELTNLPTLYKVFERC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38920-1", "uniprot_id": "MLH1_YEAST", "id": "P38920-1", "name": "DNA mismatch repair protein MLH1", "aln": "-----MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKSVASNLITFHISKVEDLNLESVDGKVCNLNFISKKSISPIFFINNRLVTCDLLRRALNSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSAIDTSRTFKASSISTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLRKAKRQENKLVRIDASQAKITSFLSSSQQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTLNESEQPRDANTINDNDLKDQPKKKQKLGDYKVPSIADDEKNALPIS--KDGYIRVPKERVNVNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDLKLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFDELN-DDASK----EKIISKIWDMSSMLNEYYSIELVNDGLDNDLKSVKLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMVPKVDTSDASLSEDEKAQFINRKEHISSLLEHVLFPCIKRRFLAPRHILK--DVVEIANLPDLYKVFERC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ** ***:*****:* *.**:**: **.:**::* *:: *: **:*:: * ***:**.: *: *:********* ****: * *:**************:::: **. . :*.::..*.:**: *** **::** * :****:*: * :**:. :*: :: :*:.**::*. .*: :* *: : . : :.** ::. ::: :*: . :. . . : : *: **. ::***:*** . *: :::::*: ***:. :**:*: : : * :********:**:** ::.*:: : :::.:.* . :::* : . .. . .:. . :: ::. :** : . . .. : * :.*:*: .::..:. * . : * :** *. . : **: :*:: : ... ***** : :* * . : : . :: : * * . :*. * : . : . : :: :*:.:.: :* * .** *:. : * : **.:: **..**:*:.* .*: : * : :* . : . :**::: .:: : .. :: . .: :::.** * ******", "identical_positions": 183, "similar_positions": 232, "identity": "23.37%" }, { "cls_id": "homologset.agr.FB:FBgn0011660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54279-1", "uniprot_id": "PMS2_MOUSE", "id": "P54279-1", "name": "Mismatch repair endonuclease PMS2", "aln": "-MEQTEGVSTECAK-----------AIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATTIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHGSASVGTRLVFDHNGKITQKTPYPRPKGTTVSVQHLFYTLPVRYKEFQRNIKKEYAKMVQVLQAYCIISAGVRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLIPFV------QLPPSDA-VCEEYGLSTSRTP-------------QNLFYVSGFISQCTHGAGRSATDRQFFFINQRPCDPAKVSKLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDANKLNVNQQ-PLLDVEGNLVKLHTAELEKPVPGKQDNSPSLKSTADEKR-VASISRLREAFSLHPTKEIKSRGPETAELTRSFPSEKRGVLSSYPSDVISYRGLRGSQDKLVSPTDSPGDCMDREKIEKDSGLSSTSAGSEEGFSTPEVASSFSSDYNVSSPEDRPSQETINCG----DLDCRPPGTGQSLKPEDHGYQCKA-LPLARLSPTNAKRFKTEERPSNVNISQRLPGPQSTSAAEVDVAIKMNKRIVLLEFS-LSSLAKRMKQLQHLKAQN-KHELSYRKFRAKICPGENQAAEDELRKEISKSMFAEMEILGQFNLGFIVTKLKED----LFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLS--DSP-GVMCRPSRVRQMFASRACRKSVMIGTALN-ASEMKKLITHMGEMDHPWNCPHGRPTMRHVANLDVISQN----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JW47-1", "uniprot_id": "A0A0G2JW47_RAT", "id": "A0A0G2JW47-1", "name": "Mismatch repair endonuclease PMS2", "aln": "-MQVGSSTRRECAK-----------AIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATSIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIREFADLTQVETFGFRGEALSSLCALSDVTISTCHVSASIGTRLVLDHNGKIIQKTPCPRPKGTTVSVQNLFYTLPVRHKEFQRNIKKEYAKMVQVLQAYCIISAGIRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLVPFV------QLPPSDS-VCEEYCLSACGTP-------------QSPFRISGFISQCTHGAGRSSTDRQFFFINQRPCDPAKVSRLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLMGMFDSDANKLSVNQQ-PLLNVEGNLVKLHTAEVGE-----QENSPSLRITAEEKR-VASVSRLREAYSLHRTTETKSWGPETPELKQSFPSQKRGVSSSCPSDIISYRGLCGSQDKLVSPTDSPGDCMDREKGEKDSGLSSTSAGSEEGFSTPEVASSFSSDCNVSSPEDRPSQENTNCGEQFLEVDDHLSGTGHHLKPEDNGYKCRASLPPTRLSPSNAKRFRTEDRPSNVGV------PQNTSAAEVDVAVKINKKIVLLDFS-LSSLAKQMKQLQHLKQQS-KSEHNYRKFRAKICPGENQAAEDELRREIRKSMFAEMEILGQFNLGFIVTKLKED----LFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFIIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLS--DSP-GVMCRPSRVRQMFASRACRKSVMIGTALS-ASEMKKLISHMGEMDHPWNCPHGRPTMRHIANLDVISQN----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54278-1", "uniprot_id": "PMS2_HUMAN", "id": "P54278-1", "name": "Mismatch repair endonuclease PMS2", "aln": "-MERAESSSTEPAK-----------AIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFV------QLPPSDS-VCEEYGLSCSDAL-------------HNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQ-PLLDVEGNLIKMHAADLEKPMVEKQDQSPSLR-TGEEKK-DVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSE-GFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFS-MSSLAKRIKQLHHEAQQS-EGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNED----IFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLS--DSP-GVMCRPSRVKQMFASRACRKSVMIGTALN-TSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GXJ5-1", "uniprot_id": "A0AC58GXJ5_DANRE", "id": "A0AC58GXJ5-1", "name": "Mismatch repair endonuclease PMS2", "aln": "-MEQQLSN-IESAG-----------AIKAIDKQSVHQICSGQVVLSLATAVKELVENSIDAGATNVDVKLKDNGIELVEVSDNGKGVEEQNYEGLTLKHHTSKLKEFSDLIHVETFGFRGEALSSLCALSDLSVVTCHESAQIGARLVYDHDGRLTQCVPHPRQHGTTVTLQKLFSTLPVRHKEFQRNIKKEYSKMIFVLQSYCIISTGVRITCSNQMGQGKRSTVLCTSGSNSMRDNIGAVFGPKQLQSLIPFR------QISPNDS-VKEDYGLGGVDVP-------------KDLFNIDGFVSQGDHGVGRSATDRQFFFINKRPCDPVKVSKLVNEVYHMYNRHQYPFVALNIAVASDCVDVNVTPDKRQILLQEEKLLLAILKSSLIAMFETGVNKISLNHISPAFTSMSRPTGTSACSDDQ---EMGSVSETLTYDGPPKT-SINLAGLKEAFSNHQAPGIGSK-QSSHKAACAGPSQKK-MLSFVSCSKKVTDFVRPPLKSPTSFTAVSSIKLSTVCSVKYKSAFDSDADGS-GAASPKSAED-DPEIKQENHSESVLHHVINKTDVKAEIVDEP--MDENLWSYETLPETKSEQHQNRIFSPEAKRARREDEPPAQNCLVDFK--SRNASLKFDAPVNIKKKTVVLPFS-QQELSKRMQRLQAQRTKSNEQEPKYRRFRAKINPGENQTAEDELKKEISKDMFKEMEIIGQFNLGFIITKIKSD----LFIIDQHATDEKYNFEMLQQNTVLKGQRLIVPQSLHLPAISETVLMENLEIFRKNGFDFLIDEDAQVMDRVKLVSLPTSKNWTFGPNDIEELIFMLS--DSP-GIMCRPSRVRQMFASRACRKSVMVGTALN-TSEMKKLVLHMGEIEQPWNCPHGRPTMRHLANLDMISQD----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA03-1", "uniprot_id": "A1ZA03_DROME", "id": "A1ZA03-1", "name": "", "aln": "MLETNYNADTEEEPDVPPPTTALSGQIKAIGKDTVHKICSGQVVLSLAVAVKELVENSIDAGATLVEIKLKDQGLQSVEVSDNGSGVEEMNLEGMTAKYHTSKIREFVDLLGVETFGFRGEALSSLCALSDMVIQTRHKSTDVGVKVELDHEGRIKKRSPCARGVGTTVLLANLFSTLPVRRRDFTRNIKKEFTKMCQILQAYCLVTKGVRILCSNHTPKGAKTIVLQTHGDQEVMANISAIFGARQAADLVPLKSPFGQGQLTEAELRADLESGADLADTTSPQISTEDVERLNQADFQLEGFISSCRHGAGRSSRDRQFFFVNSRPCDPKNIAKVMNEVYHRYNVQQQPFIYLNIITARSDVDVNLTPDKRQLLINNERILLLALKKSLLDTFGQTPATFQMQNT-TIVSMLEPKTNSGKTKFPK---ESSKDDQHEEVSEEDVP-TTSTQRFMDVLTQWRRTGDTKGTAPSVPVKRRCSESEELVTRTLKMQKIHTFLSQESPNEQSSKCEAESDAASDVDMAK-KDKTQVSLDNSFLNLKELAKESEAYDLLTKPQNTPRIDCKVLTPIKSRRSIFEFKTDAMALDKQESPAELNSQPPSFTQLSEETDIASDEDDHIELPTRIEFD---EEMEEGLPSNFSSGEITTSLEEI-ASSLKAHEQQQRDRRTRT---KLQRLRFKTEINPNQNTSAEAELQREIDKEDFARMEIIGQFNLGFIIVKLEDD----LFIVDQHATDEKYNFETLQRTTQLEYQRLAVPQNLELTAVNEMVLLNHIDVFEKNGFKFEVDHEAPATKKVRLLGKPHSKRWEFGKEDIDELIFMLQ--DAPEGTICRPSRVRAMFASRACRKSVMIGTALSRNTTMRRLITQMGEIEQPWNCPHGRPTMRHLINIAMLINSDENDEQEPPA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14242-1", "uniprot_id": "PMS1_YEAST", "id": "P14242-1", "name": "DNA mismatch repair protein PMS1", "aln": "-----------------------MTQIHQINDIDVHRITSGQVITDLTTAVKELVDNSIDANANQIEIIFKDYGLESIECSDNGDGIDPSNYEFLALKHYTSKIAKFQDVAKVQTLGFRGEALSSLCGIAKLSVITTTS-PPKADKLEYDMVGHITSKTTTSRNKGTTVLVSQLFHNLPVRQKEFSKTFKRQFTKCLTVIQGYAIINAAIKFSVWNITPKGKKNLILSTMRNSSMRKNISSVFGAGGMRGLEEVD------LVLDLNPFKNRMLGKYTDDPD---------FLDLDYKIRVKGYISQNSFGCGRNSKDRQFIYVNKRPVEYSTLLKCCNEVYKTFNNVQFPAVFLNLELPMSLIDVNVTPDKRVILLHNERAVIDIFKTTLSDYYNRQELALPKRMCSQSEQQAQKRLKTEVFDDRSTTHESDNENYHTARSESNQSNHAHFNSTTGVIDKSNGTELTSVMDGNYTNVTDVIGSECEVSVDSSVVLDEGNSSTPTKKLPSIKTDSQNLSDLNLNNFSNPEFQNITSPDKARSLEKVVEEPVYFDIDGEKFQEKAVLSQADGLVFVDNECHEHTNDCCHQERRGSTDTEQDDEADSIYAEIEPVEINVRTPLKNSRKSISKDNYRSLSDGLTHRKFEDEILEYNLSTKNFKEISKNGKQMSSIISKR-KSEAQENIIKNKDELEDFEQGEKYLTLTVSKNDFKKMEVVGQFNLGFIIVTRKVDNKYDLFIVDQHASDEKYNFETLQAVTVFKSQKLIIPQPVELSVIDELVVLDNLPVFEKNGFKLKIDEEEEFGSRVKLLSLPTSKQTLFDLGDFNELIHLIKEDGGLRRDNIRCSKIRSMFAMRACRSSIMIGKPLN-KKTMTRVVHNLSELDKPWNCPHGRPTMRHLMELRDWSSFSKDYEI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. **:* ****: .*:.*****::**:**.*. ::: :** *:: :* **** *:: * * :: *::***: :* *: *:*:***********.::.: : * . . :: * *:: . . .* **** : :** .**** ::* :.:*::::* :::.*.::. .::. * :* : :: * . : **.::** .* . : : . : :.*::*. .* **.: ****:::* ** : .: : ****: :* * * : **: . :*:*:***** :*:::*: :: :*.:* : : . . . . . . .: : . . . . . .. . : . . :. . .. * ..: . :: : : . :: : : .* * : * * .**::********:.. : * :*::****:******* ** * :: *:* ** :.*..:.* *::::: :*.****.: :*.: .:.:*:. * **. *. *.:***.::. .. * *::: *** ****.*:*:*..*. . * ::: ::.*:::*************: :: . ", "identical_positions": 189, "similar_positions": 230, "identity": "20.59%" }, { "cls_id": "homologset.agr.FB:FBgn0011661", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35763-1", "uniprot_id": "MOES_RAT", "id": "O35763-1", "name": "Moesin", "aln": "-----------------------------------------MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARVSQLEMARKKKESEAEECHQKAQMVQEDLEKTRAELKTAMSTPHVAEPAE------NEHDEQDENGAEAS---AELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTTNDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26041-1", "uniprot_id": "MOES_MOUSE", "id": "P26041-1", "name": "Moesin", "aln": "-----------------------------------------MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARISQLEMARKKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAE------NEHDEQDENGAEAS---AELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26038-1", "uniprot_id": "MOES_HUMAN", "id": "P26038-1", "name": "Moesin", "aln": "-----------------------------------------MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAE------NEQDEQDENGAEAS---ADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I42-1", "uniprot_id": "MOESA_DANRE", "id": "Q66I42-1", "name": "Moesin a", "aln": "-----------------------------------------MPKTISVRVTTMDAELEFAIQPSTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDAHTPGYLSNEKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAQRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAKEEKNHKKMERALLEDERKKREQAEKEKEKIEKEKEELMERLRVIEEQTRKAQQELEEQTRKALELEQERKRAQEEAERLERERRLAEEAKSALLQQSESQMKNQEHLATELAELTSKISLLEDAKKKKEDEALEWQTKATMVQEDLEKTKEELKNKVMSSHVTEPVHGE----NDNDEGDESSAEAS---AELTSAAAYKDRSEEERMTEAEKNERVQKHLLALTSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5PQK5-1", "uniprot_id": "Q5PQK5_RAT", "id": "Q5PQK5-1", "name": "", "aln": "MKRKLSERICRVPGKATVSAKAIIVYRSEEFLKKVTNKKRKMPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQKELEEQTRKALELEQERQRAKEEAERLDRERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMCAPPPPPPPAVVPPTENEHDEQDEHSAEAS---AELSSEGVTNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSSIKQM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26043-1", "uniprot_id": "RADI_MOUSE", "id": "P26043-1", "name": "Radixin", "aln": "-----------------------------------------MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTVKAQKELEEQTRKALELEQERQRAKEEAERLDRERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEQDENSAEAS---AELSSEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35241-1", "uniprot_id": "RADI_HUMAN", "id": "P35241-1", "name": "Radixin", "aln": "-----------------------------------------MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEAS---AELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31977-1", "uniprot_id": "EZRI_RAT", "id": "P31977-1", "name": "Ezrin", "aln": "-----------------------------------------MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVADELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDFEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26040-1", "uniprot_id": "EZRI_MOUSE", "id": "P26040-1", "name": "Ezrin", "aln": "-----------------------------------------MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVAEELIQDITQKLFFLQVKDGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDYEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15311-1", "uniprot_id": "EZRI_HUMAN", "id": "P15311-1", "name": "Ezrin", "aln": "-----------------------------------------MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46150-1", "uniprot_id": "MOEH_DROME", "id": "P46150-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "----------------------------------------MSPKALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKK-------QQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQHHHVAE-DENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:.***************..*************:******:***:* *.*. .**:** *** *:*:**.*: *:*****:****::****: * :**:****:.**.*:*******:***.*****::..*.** *..*:*:.::*:****::***:.:::**: * * **:.**::.:::*************:***.*:****::**************::*::****************.:***:***********:*:* *:******* ******************:********:***: *: ** *: ** .*:: ::* :*: ::. :::::* * .*::: :: : :.* : . : . : : :* *: .: :: . *:.*. . : .. .: . : : :. . : :: . :* .. *: * * :::***:: :* :*..:*:::***.*.* ** :* **:: *********:**.****:*:*:** : ", "identical_positions": 276, "similar_positions": 162, "identity": "42.59%" }, { "cls_id": "homologset.agr.FB:FBgn0011666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58GII9-1", "uniprot_id": "A0AC58GII9_DANRE", "id": "A0AC58GII9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEADASQVTSGSLN-------DSQHDPGKMFIGGLSWQTSPDSLRDYFCKFGEIRECMVMRDPTTKRSRGFGFITFADVSSVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSASTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRDLRRREELTMTTGFKSNEEVLQKAGFGFVTFENEDIVEKVCEIHFHEINNKMVECKKAQPKEVMFPP-------------------------GTRGRARSLPYTMDAFMLG---MGMLSYPNIVATYGRGYTGFSPSYSYQFPGFPATAYGPVAAAAVAAARGSGRATRGRSGYMAYPQNAGPGFPDYGFYSGPGDQRAAPCSFADYATLGPHTGQMLQSEHVTSTCNSPSQHH----------PSPDHFKSSGANPPRPGGFPGANSPGPVADLYGPSSQDSA-VGNYISAASPQPGSGFN---------HSIAGPLIATAFTNGYH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B3X4-1", "uniprot_id": "A0A8M2B3X4_DANRE", "id": "A0A8M2B3X4-1", "name": "RNA-binding protein Musashi homolog 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGDGSQATSGSPN-------DSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHR------------------------GFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPP-------------------------GTRGRARGLPYTMDAFMLG---MGMLSYPNIVATYGRGYTGFAPSYSYQFPGFPATAYGPVAAAAAVAA------ARG----------------------------------------------------------------------------------SGTNPPRPGAFPGASSPGPVADLYGPTSQDSG-VGNYISAASPQPGSGFG---------HSIAGPLIATAFTNGYH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMS8-1", "uniprot_id": "Q8IMS8_DROME", "id": "Q8IMS8-1", "name": "", "aln": "MLFENPAVAAKLPFPYNVPPPLQAAAAAAAAVPNLRFQTPIKAFACLTAATRSVSEMNATSLYAGNPMENAAAAAAAAAAGLIDPHHNRDLHQALVASIANNSVAAIGGGLTTAAVLKSAAQQSQQAVQQNQNAVVVTPGLEQPKQEPAQQAALALLKENVNASAGAGQNNGQAAMGGSNKSGSSGRSTPSLSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPK-NRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHR------------------------GFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTAPGQLIGARGAGVATMNPLAMLQNP---TQLLQSPAAAAAAQQAALISQNPFQVQNAAAAASIANQAGFGKLLTTYPQTALHSVRYAPYSIPASAATANAALMQAHQAQSVAAAAHHHQQQQQQQHHHQQQTHNAHVAAAQQQQQSHHNAVSNPASQAHSAAAAAALAANAANGAGAAGAHSLAAAAQQAGLMAGNPLNAAAAAAAAAANPAAAYSNYALANVDMSSFQGVDWSTMYGMGMYV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99383-1", "uniprot_id": "HRP1_YEAST", "id": "Q99383-1", "name": "Nuclear polyadenylated RNA-binding protein 4", "aln": "--MSSDEEDFNDIYGDDKPTTTEEVKKEEEQNKAGSGTSQLDQLAALQALSSSLNKLNNPNSNNSSSNNSNQDTSSSKQDGTANDKEGSNEDTKNEKKQESATSANANANASSAGPSGLPWEQLQQTMSQFQQPSSQSP------------------------------------PQQQVTQTKEERSK------ADLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKT-QHILDGKVIDPKRAIPRDEQDK----TGKIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSR------------------------GFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPRHMQQKSSN----------------------NGGNNGGNNMNRRGGNFGNQGDFNQMYQNPMMGGYNPMMNPQAMTDYYQKMQEYYQQMQKQTGMDYTQMYQQQMQQMAMMMPGFAMPPNAMTLNQPQQDSNATQGSPAPSDSDNNKSNDVQTIGN----------------------------TSNTDSGSPPLNLPNGPKGPSQYNDDHNSGYGYNRDRGDRDRNDRDRDYNHRSGGNHRR--------NGRGGRGGYNRRNNGYHPYNR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .. . . . . *:*:***.*:*: *.*::** :* : : :*:**.* *******::* . .:*::*: * **.* **** * *: : : * ******:. .. ::.: :*.*:* : :: :::*: * : * ******::. * *::**: :* :::: :* *:*:*:. . * .. . : : . * . : : .. * .. .. . : . .... . . * . * : ", "identical_positions": 69, "similar_positions": 97, "identity": "10.38%" }, { "cls_id": "homologset.agr.FB:FBgn0011672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54902-1", "uniprot_id": "NRAM2_RAT", "id": "O54902-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLDPEEKIPDDGASGDHGDSASLG----AINPAYSNSSLPHSTGDSEEPFTTYFD-EKIPIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLD------KYGLRKLEAFFGFLITIMALTFGYEYVTVKPS--QSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQE---------------------VREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSP-HADLFPNDNS----TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHV-ALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCG---------RSYHLGLTARPEIYLLNTV----DAVSLVSR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49282-1", "uniprot_id": "NRAM2_MOUSE", "id": "P49282-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLDPKEKMPDDGASGDHGDSASLG----AINPAYSNSSLPHSTGDSEEPFTTYFD-EKIPIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLWGGVLITIADTFVFLFLD------KYGLRKLEAFFGFLITIMALTFGYEYITVKPS--QSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQE---------------------VREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSP-HADLFPSDNS----TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLIVCSINMYFVVVYVQELGHV-ALYVVAAVVSVAYLTFVFYLGWQCLIALGLSFLDCG---------RSYRLGLTAQPELYLLNTV----DADSVVSR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49281-1", "uniprot_id": "NRAM2_HUMAN", "id": "P49281-1", "name": "Natural resistance-associated macrophage protein 2", "aln": "MVLGPEQKMSDDSVSGDHGESASLG----NINPAYSNPSLSQSPGDSEEYFATYFN-EKISIPEEEYS--CFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLD------KYGLRKLEAFFGFLITIMALTFGYEYVTVKPS--QSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQE---------------------VREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSP-HAGLFPKDNS----TLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHV-ALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDCG---------HTCHLGLTAQPELYLLNTM----DADSLVSR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41251-1", "uniprot_id": "NRAM1_MOUSE", "id": "P41251-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MISDKSP-PRLSRPSYG----SISSLPG---PAPQPAPCRE---TYLS-EKIPIPSADQG--TFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWDGVLITIVDTFFFLFLD------NYGLRKLEAFFGLLITIMALTFGYEYVVAHPS--QGALLKGLVLPTCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRVD---------------------VREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLQNYAKIFPRDNN----TVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLKDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGRMSKAITSCIMALVCAINLYFVISYLPSLPHP-AYFGLVALFAIGYLGLTAYLAWTCCIAHGATFLTHS---------SHKHF-------LYGLPNE----EQGGVQGSG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70553-1", "uniprot_id": "NRAM1_RAT", "id": "P70553-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MIRDKNP-QRVNRPSYG----SISSLPS---PAPQPEPSRN---TYLS-EKIPIPSTEQ-------------------------------------------LLWVLLWATVLGLLCQRLAARLGVVTGKDLGEICHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWGGVLITIVDTFFFLFLD------NYGLRKLEAFFGFLVTIMALTFGYEYVVARPS--QGALLKGLFLPSCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRGD---------------------VREANMYFLTEATIALFVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLHNYAKIFPRDNN----TVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGWLSKVITSCIMALVCAINLYFVISYLPSLPHP-AYFGLVALLAIGYLGLTAYLAWTCCIAHGAKFLTHS---------SHQRF-------LYGLPIE----EQEGREGSG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49279-1", "uniprot_id": "NRAM1_HUMAN", "id": "P49279-1", "name": "Natural resistance-associated macrophage protein 1", "aln": "--------MTGDKGP-QRLSGSSYG----SISSPTSPTSPGPQQAPPRE---TYLS-EKIPIPDTKPG--TFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVDTFFFLFLD------NYGLRKLEAFFGLLITIMALTFGYEYVVARPE--QGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRAD---------------------IREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNA----TVAVDIYQGGVILGCLFGPAALYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAINLYFVVSYLPSLPHP-AYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHS---------SHHHF-------LYGLLEE----DQKG-ETSG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49283-2", "uniprot_id": "MVL_DROME", "id": "P49283-2", "name": "Protein Malvolio", "aln": "MSSNEAYHEPGAGGDGPGGSSGASGGGSQRSNQLHHQQILNETTYLKPAAKQAYFSDEKVLIPDDDSTNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLD------KYGLRKLEFLFGTLITIMAVSFGYEYIVSAPN--QGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKK---------------------VSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVENMEIKGGLLALVCIFAILYILFNLYLVIHMAACMGNQRLMNSRWVQRFVLPSQNSFSIKNANSTYARIATSSDQEPEGLAGEDA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38778-1", "uniprot_id": "SMF2_YEAST", "id": "P38778-1", "name": "Manganese transporter SMF2", "aln": "--------------------MTSQEYEPIQWSDESQTNNDSVNDAYADVNTTHESRRRTTLQPNSTSQSMIGTLRKYARFIGPGLMVSVSYMDPGNYSTAVAAGSAHRYKLLFSVLVSNFMAAFWQYLCARLGAVTGLDLAQNCKKHLPFGLNITLYILAEMAIIATDLAEVVGTAISLNILFH--IPLALGVILTVVDVLIVLLAYKPNG-SMKGIRIFEAFVSLLVVLTVVCFTVELFYAKLG-PAKEIFSGFLPSKAVFE-GDGLYLSLAILGATVMPHSLYLGSGVVQPRLREYDIKNGHYLPDAND------------MDNNHDNYRPSYEAISETLHFTITELLISLFTVALFVNCAILIVSGAT---------LYGSTQN----AEEADLFSIYNLLCSTLSKGAGTVFVLALLFSGQSAGIVCTLSGQMVSEGFLNWTVSPALRRSATRAVAITPCLILVLVAGRSGLSGALNASQVVLSLLLPFVSAPLLYFTSSKKIMRVQLNRTKELSRTTDKKPVADRTEDDETIELEEMGIGSSSQERSLVSPAPEYKDMSNGMIVTVLAIIVWLIISGLN--------------------FYMLLGF----TTGKEVHL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12078-1", "uniprot_id": "SMF3_YEAST", "id": "Q12078-1", "name": "Iron transporter SMF3", "aln": "------------------------------------------------------------------MRSYMQILQKFAKFIGPGILVSVAYMDPGNYATSVSGGAQYKYTLLFSIFISNIFAVLLQCLCVKLGTITGYDLAENCRHNLPKKLNYTLYLFAEVAIIATDLAEVVGTAIALQILFK--IPLTWGVLLTVLDVLVILMFYTPNGQSLKKVRVFEFGVGILVIGTCICFVLELFKVSIP-DKAELFKGFLPSNIIFKEQQALYISLGILGATVMPHSLYLGSSIVKPRLHDYDLKK-----------------------YGKVNARPSLSAIKYTLNYAYAELIISLFLIATFVNSAILIVAGAT---------LSGQPE-----AEDADLLSIYKLLVHYISPAAGLIFALAMLCSGQSAGIICTLAGQIVSEGFLQWSLPPWATRLCTRLIAIVPCLFVTLTMGEKGISDILNFSQVVLSLILPIVSAPLIYFTANRKLMVVHD-ENGVVRAPADVNAIADETT-------------------PLNSKHSKIVDFTNSRLLTYTSVFVWALIGSLN--------------------CYLVISY----LLGADIHF--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38925-1", "uniprot_id": "SMF1_YEAST", "id": "P38925-1", "name": "Manganese transporter SMF1", "aln": "-MVNVGPSHAAVAVDASEARKRNISEEVFELRDKKDSTVVIEGEAPVRTFTSSSSNHEREDTYVSKRQVMRDIFAKYLKFIGPGLMVSVAYIDPGNYSTAVDAGASNQFSLLCIILLSNFIAIFLQCLCIKLGSVTGLDLSRACREYLPRWLNWTLYFFAECAVIATDIAEVIGTAIALNILIK--VPLPAGVAITVVDVFLIMFTYKPGASSIRFIRIFECFVAVLVVGVCICFAIELAYIPKSTSVKQVFRGFVPSAQMFD-HNGIYTAISILGATVMPHSLFLGSALVQPRLLDYDVKHGNYTVSEEQDKVKKSKSTEEIMEEKYFNYRPTNAAIKYCMKYSMVELSITLFTLALFVNCAILVVAGST---------LYNSPE-----ADGADLFTIHELLSRNLAPAAGTIFMLALLLSGQSAGVVCTMSGQIVSEGHINWKLQPWQRRLATRCISIIPCLVISICIGREALSKALNASQVVLSIVLPFLVAPLIFFTCKKSIMKTEITVDHTEEDSHNHQNNNDRSAG------SVIEQDGSSGMEIENGKDVKIVYMANNWIITVIAIIVWLFLSLLN--------------------VYAIVQLG---MSHGDIS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: :.... : * *. :** :** .*.. * . *:: * *::.:*: **:*:**:: :* :** ** :*: *.: .:: :* :* .. *: : * * :: *:. . : ::.::** :***.::* *.:*:.* : : : : : :::* . : : . . : : .*: .* :. * :: :.:* :***: : * :**: **.:. ** :* * . : : :: : :.: *: **: * : **. :* : : * ", "identical_positions": 65, "similar_positions": 111, "identity": "10.4%" }, { "cls_id": "homologset.agr.FB:FBgn0011674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFP7-1", "uniprot_id": "D3ZFP7_RAT", "id": "D3ZFP7-1", "name": "Protein inscuteable homolog", "aln": "------------------------------MRRPPGDGDSTGEGPGNWGLWG----------AQESRRLCCVGPDRCG------------------------------------QALLQIGMNMMALP------------------------------------GGRHLGSIPLQEQR------LHFMQVDSVQRWMED-----LKLMTECECMCVLQAKPISLEEDTQSDLILAGGPGP-----------------------------------GDPLQLLLKRGWVISTELRRIGQKLAQ---------------DRWAR----------------------------------VHSMSVRLTCHARSMVSEYSTISRTTSQEMGQAEKLLMEKCSELSAVTER---------CLQVENEHVLKSMKACVSET------------------LSMLGQHFGQLLELALTREVQALVRKIDTSDNIYITES---TTGNLFSLTQEG-APLCRIIAKEGGVVALFKVCRQDTFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLTDILTDDSHS---EATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFEKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRS--GTPAEVAACERVQQKAAVTLARLCRD--------------PDVAREAVRLSCMSR-------------LIELCRSPSERNSSDAVLVACLAALR-----------RLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3HNM7-1", "uniprot_id": "INSC_MOUSE", "id": "Q3HNM7-1", "name": "Protein inscuteable homolog", "aln": "------------------------------MRRPPGDGDSTGEGPGNWGLWG----------AQESRRLCCVGPDRCG------------------------------------QALLQIGINMMALP------------------------------------GGRHLDSVPLQEQR------LHFMQVDSVQRWMED-----LKLMTECECMCVLQAKPISLEEDTQGDLILAGGPGP-----------------------------------GDPLQLLLKRGWVISTELRRIGQKLAQ---------------DRWAR----------------------------------VHSMSVRLTCHARSMVSEYSTISRTASQEMGQAEKLLMEKCSELSAVTER---------CLQVENEHVLKSMKACVSET------------------LSLLGEHFGQLLELALTREVQALVRKIDTSDNIYITES---TTGNLFGLTQEG-APLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLADILTDESHS---EATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFDKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCGSDIIQENGVQLIMGMLSEKPRS--GTPAEVAACERVQQKAAVTLARLCRD--------------PDVAQEAVRLSCMSR-------------LIELCRSPSERNSSDAVLVACLAALR-----------RLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1MX18-1", "uniprot_id": "INSC_HUMAN", "id": "Q1MX18-1", "name": "Protein inscuteable homolog", "aln": "------------------------------MRRPPGNGEAASEGPGGWGLWG----------VQESRRLCCAGHDRCK------------------------------------QALLQIGINMMALP------------------------------------GGRHLDSVTLPGQR------LHLMQVDSVQRWMED-----LKLMTECECMCVLQAKPISLEEDAQGDLILAGGPGP-----------------------------------GDPLQLLLKRGWVISTELRRIGQKLAQ---------------DRWAR----------------------------------VHSMSVRLTCHARSMVSEYSAVSRNSLKEMGEIEKLLMEKCSELSAVTER---------CLQVENEHVLKSMKACVSET------------------LSMLGQHFGQLLELALTREVQALVRKIDASDNIYTTES---TTGNLFSLTQEG-APLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGVLCLADILTDNSHS---EATRAEAAAVVAQVTSPHLPVTQHLSSFLESMEEIVTALVKLCQEASSGEVFLLASAALANITFFDTMACEMLLQLNAIRVLLEACSDKQRVDTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRS--GTPAEVAACERVQQKAAVTLARLSRD--------------PDVAREAVRLSCMSR-------------LIELCRSPSERNSSDAVLVACLAALR-----------RLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2R4-1", "uniprot_id": "Q9W2R4_DROME", "id": "Q9W2R4-1", "name": "", "aln": "MSFQRSYSKVWWGSEQSSLTSGGFYSSFSGGSSTSSTSNYPQRQPASLGPLGNLSCIQEVEDEQNSSKLSWHKHDSPGSLRSQDSGFSDNEESHQLQHQQNLSPPSPQSDKQQTPAATPTSVHSVATPPTVVRRVGNSSFYSPLISVTRRISFTSGQITPKTRSGDEDAEDAELEASRSRLFEQLDSMKLDDGEAEAEEDSPPRPAIRRRRRLMRKPMPEPEAASASEEEEVVIAPPPPPPYNNETVYLGEAPPPYNNETVTFGATEQDESLQQQPSPLRVRSLR-FTASTSTPKSGSKIAKRGKKHPEPVASWMSEQRWAGEPEVMCTLQHKSIAQEAYKNYTITTSAVCKLVRQLQQQALSLQVHFERSERVLSGLQASSLPEALAGATQLLSHLDDFTATLERRGVFFNDAKIERRRYEQHLEQIRTVSKDTRYSLERQHYINLESLLDDVQLLKRHTLITLRLIFERLVRVLVISIEQSQCDLLLRANINMVATLMNIDYDGFASLSDAFVQNEAVRTLLVVVLDHKQSSVRALALRALATLCCAPQAINQLGSCGGIEIVRDILQVESAGERGAIERREAVSLLAQITAAWHGSEHRVPGLRDCAESLVAGLAALLQPECCTQTLLLCAAALNNLSRMEATSHYSIMSNEAIFRLIDTLEHQTCGTSVFLYEQIVGMLHNMSLNKKCHSHLANGVIINFITSVYQTEFYQTYGSRAESDAQRRTIKTILHTLTRLASDSPTLGAELLEQWHLPDLLRQSLALKPANSQQQQHLDSSYGGDISQLARQLLRAHGQEQQLLQATPAPGGSFSSGHQTPEAQTQTNSSGMSSSGSKTKAKSSASPLLKFNLTRQESFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... .: . . *.. * * *:* :*. * * .:: :* * *... . * .* *. *::*. : *: : . . * .:* : . . : ::::* * * .**:: * :. **. : *.*:*: :*** ::. :: * * . * :. .: * . *:.: .:::*. ** : . *: *:.::: .:* :.:* .* *.* : * *:.** .*: *: .: ...*:.: :* *.*. :.:: .* :*: * :.. .: . ***:**::**. :.::** . .*: : *** :* . * **.:::**:*:. :::..: : *.:*:.* * * .. :.:**.:*** *:: :: : ::. :** *::: .: : : :*** :* ***: ::* *.: : :::* .: . : . *: ** * .*. :. **:**. * **: :::: *. . : :*.*. . :..: *: . .* : . ..*:..*. : .:. : : . :****", "identical_positions": 128, "similar_positions": 228, "identity": "14.88%" }, { "cls_id": "homologset.agr.FB:FBgn0011676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62600-1", "uniprot_id": "NOS3_RAT", "id": "Q62600-1", "name": "Nitric oxide synthase 3", "aln": "------------------------------------------------------------------------------------------------MGNLKSVGQE-------PGP------------------------PCG--------------------------------------------------------------------------------------------------------------LGLGLGLGLCGKQGPASPAPEPS---------QAPVPPSPTRPAPDHSPP---LTRPPDG----------PKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPTQGPSPTEQLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVVATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRYAGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFTLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLYSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAK---GTGITRKKT----FKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP--------------RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDA--KAAARDIFSPKRSWKRQRYRLSTQAESLQLLPRLTHVHRRKMFQATILSVEN--LQSSKSTRATILVRLDTGS-QEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLE-KGSPGGPPPGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPFRGFWQDRLHDIEIK-GLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDPGSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGSMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPTQETPGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70313-1", "uniprot_id": "NOS3_MOUSE", "id": "P70313-1", "name": "Nitric oxide synthase 3", "aln": "------------------------------------------------------------------------------------------------MGNLKSVGQE-------PGP------------------------PCG--------------------------------------------------------------------------------------------------------------LGLGLGLGLCGKQGPASPAPEPS---------QAPAPPSPTRPAPDHSPP---LTRPPDG----------PRFPRVKNWEVGSITYDTLSAQAQQDGPCTSRRCLGSLVFPRKLQSRPTQGPSPTEQLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLIRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFTLPPEMVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAK---GAGITRKKT----FKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP--------------RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDA--KAAARDIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVEN--LQSSKSTRATILVRLDTGG-QEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLE-KGSPGGPPPGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYEEWKWFSCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTIAVLAYRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPFRGFWQDRLHDIEIK-GLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDPGSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGGMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPGPEIPGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29474-1", "uniprot_id": "NOS3_HUMAN", "id": "P29474-1", "name": "Nitric oxide synthase 3", "aln": "------------------------------------------------------------------------------------------------MGNLKSVAQE-------PGP------------------------PCG--------------------------------------------------------------------------------------------------------------LGLGLGLGLCGKQGPATPAPEPS---------RAPASLLP--PAPEHSPPSSPLTQPPEG----------PKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAK---GTGITRKKT----FKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP--------------RPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDA--KAAARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVEN--LQSSKSTRATILVRLDTGG-QEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLE-KGSPGGPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESK-GLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTNSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29476-1", "uniprot_id": "NOS1_RAT", "id": "P29476-1", "name": "Nitric oxide synthase 1", "aln": "----------------MEENTFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTIRVTQPLGPP--TKAVDLSHQPSASKDQSLAVDRVTGLGNGPQHAQGHGQGAGSVSQANGVA-----IDPTMKSTKANLQDIGEHDELLKEIEPVLSILNSGSKATNRGGPAKAEMKDTGIQVDRDLDGKSHKAPPLGGDNDRVFNDLWGKDNVPVILNNPYSEKEQSPTSGKQSPTK---NGSPSRCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPSQHTRKP-EDVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWK---GTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKAMSMEEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ-----------------EERKSYKVRFNSVSSYSDSRKSSGDGPDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKPNNSLISNDRSWKRNKFRLTYVAEAPDLTQGLSNVHKKRVSAARLLSRQN--LQSPKFSRSTIFVRLHTNG-NQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSWLNRIQADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHK-GMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKK-DADEVFSS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0J4-1", "uniprot_id": "NOS1_MOUSE", "id": "Q9Z0J4-1", "name": "Nitric oxide synthase 1", "aln": "----------------MEEHTFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTIRVTQPLGTP--TKAVDLSRQPSASKDQPLAVDRVPGPSNGPQHAQGRGQGAGSVSQANGVA-----IDPTMKNTKANLQDSGEQDELLKEIEPVLSILTGGGKAVNRGGPAKAEMKDTGIQVDRDLDGKLHKAPPLGGENDRVFNDLWGKGNVPVVLNNPYSENEQSPASGKQSPTK---NGSPSRCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEQICMGSIMLPSHHIRKS-EDVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVEFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWK---GTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKAMSMEEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ-----------------EERKSYKVRFNSVSSYSDSRKSSGDGPDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSNVHKKRVSAARLLSRQN--LQSPKSSRSTIFVRLHTNG-NQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSWLNRIQADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHK-GMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKK-DTDEVFSS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29475-1", "uniprot_id": "NOS1_HUMAN", "id": "P29475-1", "name": "Nitric oxide synthase 1", "aln": "----------------MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTIRVTQPLGPP--TKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAPRPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQVDRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTK---NGSPSKCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRP-EDVRTKGQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWK---GTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ-----------------EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQN--LQSPKSSRSTIFVRLHTNG-SQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHK-GMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKK-DTDEVFSS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IQG7-1", "uniprot_id": "A0A0R4IQG7_DANRE", "id": "A0A0R4IQG7-1", "name": "Nitric oxide synthase", "aln": "----------------MQESEPSVCQLQPNIISVRLFKRKIGGLGFLVKQRVCKPPVIVSDLIRGGAAEECGLVQVGDIVLAVNNKPLVDMSYERALETLKNVSPESHAVLILRGPEGFTTHLETTLSSDGKTKTIRVTRPVNPAQSRPCERCSPLTPNMTKELRAIENLSSSSTPRKESRDDKPLIPLLSQDSLLR--------EGGHAGLLLNGVEDNNDLLKEIEPVLKLIKNSKKEINGEGQRVIDRKDAEVQVERDLGVGNGQNAQLASDNDRVFDDLWRKDNMPTVLNNPYSESDKPQSYERVSPTKAVQNGSPSKCPRFMKVKNWETGALYNDTLHHSSSKVPICTEHVCIGSIMVPNQHAHKP-DEDRRKEELLPLATDFIDQYYTSIKRCCSKAHVDRLEEVKKEIETSGTYQLKDTELIYGAKHAWRNAARCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQKTDGKHDFRVWNSQLIRYAGYKQPDGSILGDPASVELTEICMQQGWKAPKGRFDVLPLLLQANGNDPELFEIPDDLVLEVPIIHPKFEWFKELNLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDFCDSSRYNILEEVATMMGLDTRKTSSLWKDQALVEINIAVLYSYQMSKVTIVDHHSATESFMKHMENEYRVRGGCPGDWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWK---GVNGTPTKKRAIGFKKLAKAVKFSAKLMGQAMAKRVKATILFATETGKSQDYAKTLCEIFKHAFDAKVMSMDEYDTVDLEHETLVIVVTSTFGNGDPPENGEKFGAALMEMRHPTTSV-----------------EDRKTYKVRFNSVSSYSDTRKSSSDEPESKANFESTGPLANVRFSVFGLGSRAYPHFCAFAHAVDTLFEELGGERILRMGEGDELCGQEESFRTWAKKVFKAACDVFCVGDDVNIEKANDSLISNDRSWKKSKFRMTYTAEAPTLTQALYSIHKKKVYGAKVVQRQN--LQSARSNRLTIFVRLDANN-HESLKYLPGDHLGVFPGNNEDLVTTLIEKLEDAPPVNQIVKVEFLEERNTALGVISNWTDESRIPPCTIYQAFKYFLDITTPPSPVLLQQFAPLATNEKQRKRLEVLSKGLQEYEEWKWYNNPTMVEVLEEFPSLQIPSTLLLTQLPLLQPRYYSISSSPDLYPGEIHLTVAVVSYRPRDGEGPIHHGVCSSWLNSLDEGDTVPCFVRGAPSFRMPKDSQVPCILIGPGTGIAPFRAFWQQRQYDVENK-GIKACPMILVFGCRQSQIDHIYKEQTIQAKNKEVFKELYTAYSREPGRPKKYVQDVLREQLSETVYKCLREEGGHIYVCGDVTMAGDVLKTVQQIFKLHGNMSLEDAGFYISKLRDENRYHEDIFGVTLRTYEVTNRLRSESIAYIEESKK-DIDEVFCS--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06518-1", "uniprot_id": "NOS2_RAT", "id": "Q06518-1", "name": "Nitric oxide synthase, inducible", "aln": "-------------------------------------------------------------------------------MACPWKFLFRVKSYQGDLKEEKDINNN-------------------------------------------------------------------------------------------------------------------------------------------------------VEKTPGAIPSPTTQDDPKSH------KHQNGFPQFLTGTAQNVPESLDKLHVTPSTR---------PQHVRIKNWGNGEIFHDTLHHKATSDISCKSKLCMGSIMNSKSLTRGPRDKPTPVEELLPQAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARSCSTASEMFQHICRHILYATNSGNIRSAITVFPQRSDGKHDFRIWNSQLIRYAGYQMPDGTIRGDPATLEFTQLCIDLGWKPRYGRFDVLPLVLQAHGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINAAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQ---DEKLRPRRRE-IRFTVLVKAVFFASVLMRKVMASRVRATVLFATETGKSEALARDLAALFSYAFNTKVVCMEQYKANTLEEEQLLLVVTSTFGNGDCPSNGQTLKKSLFMMKELGHTF-----------------------------------------------------------RYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEDAFRSWAVQTFRAACETFDVRSKHCIQIPKR--YTSNATWEPEQYKLTQSPESLDLNKALSSIHAKNVFTMRLKSLQN--LQSEKSSRTTLLVQLTFEG-SRGPSYLPGEHLGIFPGNQTALVQGILERVVDCSSPDQTVCLEVLDES------GSYWVKDKRLPPCSLRQALTYFLDITTPPTQLQLHKLARFATEETHRQRLEALCQP-SEYNDWKFSNNPTFLEVLEEFPSLRVPAAFLLSQLPILKPRYYSISSSQDHTPSEVHLTVAVVTYRTRDGQGPLHHGVCSTWINNLKPEDPVPCFVRSVSGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDSQHR-GLKGGRMTLVFGCRHPEEDHLYQEEMQEMVRKGVLFQVHTGYSRLPGKPKVYVQDILQKELADEVFSVLHGEQGHLYVCGDVRMARDVATTLKKLVAAKLNLSEEQVEDYFFQLKSQKRYHEDIFGAVFSYGAKKGNTLEEPKGTRL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29477-1", "uniprot_id": "NOS2_MOUSE", "id": "P29477-1", "name": "Nitric oxide synthase, inducible", "aln": "-------------------------------------------------------------------------------MACPWKFLFKVKSYQSDLKEEKDINNN-------------------------------------------------------------------------------------------------------------------------------------------------------VKKTPCAVLSPTIQDDPKS--------HQNGSPQLLTGTAQNVPESLDKLHVT-STR---------PQYVRIKNWGSGEILHDTLHHKATSDFTCKSKSCLGSIMNPKSLTRGPRDKPTPLEELLPHAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARNCSTAQEMFQHICRHILYATNNGNIRSAITVFPQRSDGKHDFRLWNSQLIRYAGYQMPDGTIRGDAATLEFTQLCIDLGWKPRYGRFDVLPLVLQADGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQ---NEKLRPRRRE-IRFRVLVKVVFFASMLMRKVMASRVRATVLFATETGKSEALARDLATLFSYAFNTKVVCMDQYKASTLEEEQLLLVVTSTFGNGDCPSNGQTLKKSLFMLRELNHTF-----------------------------------------------------------RYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEDAFRSWAVQTFRAACETFDVRSKHHIQIPKR--FTSNATWEPQQYRLIQSPEPLDLNRALSSIHAKNVFTMRLKSQQN--LQSEKSSRTTLLVQLTFEG-SRGPSYLPGEHLGIFPGNQTALVQGILERVVDCPTPHQTVCLEVLDES------GSYWVKDKRLPPCSLSQALTYFLDITTPPTQLQLHKLARFATDETDRQRLEALCQP-SEYNDWKFSNNPTFLEVLEEFPSLHVPAAFLLSQLPILKPRYYSISSSQDHTPSEVHLTVAVVTYRTRDGQGPLHHGVCSTWIRNLKPQDPVPCFVRSVSGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDSQHK-GLKGGRMSLVFGCRHPEEDHLYQEEMQEMVRKRVLFQVHTGYSRLPGKPKVYVQDILQKQLANEVLSVLHGEQGHLYICGDVRMARDVATTLKKLVATKLNLSEEQVEDYFFQLKSQKRYHEDIFGAVFSYGAKKGSALEEPKATRL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35228-1", "uniprot_id": "NOS2_HUMAN", "id": "P35228-1", "name": "Nitric oxide synthase, inducible", "aln": "-------------------------------------------------------------------------------MACPWKFLFKTKFHQYAMNGEKDINNN-------------------------------------------------------------------------------------------------------------------------------------------------------VEKAPCATSSPVTQDDLQYHNL---SKQQNESPQPLVETGKKSPESLVKLDATPLSS---------PRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQ---DEKRRPKRRE-IPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKELNNKF-----------------------------------------------------------RYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKL--YTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQN--LQSPTSSRATILVELSCED-GQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDES------GSYWVSDKRLPPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQP-SEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHK-GVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDRVAVQPSSLEMSAL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIN8-1", "uniprot_id": "A2BIN8_DANRE", "id": "A2BIN8-1", "name": "Nitric oxide synthase", "aln": "---------------------------------------------------------------------------------------------MGRQAQTTIIEN---------------------------------------------------------------------------------------------------------------------------------------------------------EKQTVQSKRPVDR---------------------------------------PIRC---------PFAVQLRNYKDGSTHQDSLHHKAAKNTPCNSKTCEGSIMNPKPLIRGPSKITPSPDDMLSQAEDFIDQYYKSLKIPGSTEQQARIDRIALEITLTGTYSLTTEELAFGAKQAWRNAPRCIGRIQWSNLQLFDARDCKTAEDMFHALCTHLKYATNGGNLRSAITVFPQRTDEGHDFRVWNGQLIKYAGYQMDDGSVIGDPAGVDFTQVCIQLGWKPKYGRFDVLPLVLQANGEDPEVFEIPPELILEVPIEHPEYEWFKDLDLKWYAIPAVANMLMEVGGLEFTACPFNGWYMGTEIGVRDFCDSQRYNILERVGQLMGLETRKLSSLWKDQALVAINVAVIHSYQKNKVTITDHHSASESFMQHLETEVRLRGGCPADWVWLVPPMSGSLTPVYHQELLNYILSPFFYYQTDPWLTHKWK---DEKKGLRRCK-VSFKGLIRAVFFSQTLIKAVLAKRVRCTVLYATETGKSLSFAKKLNTMLNRAFDSRLVCMEEYDFSELETETLLMVVTSTFGNGESPGNGVTFRKQLFSLQKVKNTI-----------------------------------------------------------RYGVFGLGSRVYPQFCAFAHAVDDKLAELGAKRMTATGEGDELNGQDEAFSAWACTAFKDACEEFNIKK----QLKAV--EEQTEGWDPQRYRVQQDSCTLDPITALSALHSKTVFPMTLKRRQK--LQSAQSSRSTILVELKTDGNTDALKFAPGDHVGIFPENSSELVHGIVKHLPDATPDNQSLRLETLSESSHE---GKRWQTDERLPACTLVQALTYFLDVTTPPSQSLLRKLSTVADQEEDRKRLEALASDFQEYSTWKDFYRPTFLEVLEEFPSLKVPSAFILSQIPLLKPRLYSVSSSLDHHPNELHLTISVVEYQTQGGAGPMHFGTCSTWFNTIKRGHTVPCFVHRSGGFHLPEDPSTPVLLIGAGSGIAPFRSFWQQRTQDVKKT-GQQISPMTLLFGCRDSETDHLYKVETLKLRLNGILGNVNTAYSRQPGKPKMYVQDVLKEQLVEKALEVLHKSAGHLYVCGGMNMAKDVAQTLKDILVNNTIMSEVEAGEYMDMLKVEKRYHEDIFGA-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27571-1", "uniprot_id": "NOS_DROME", "id": "Q27571-1", "name": "Nitric oxide synthase", "aln": "MSQHFTSIFENLRFVTIKRSTNAQQQQQQQQQQLQQQQQQLQQQKAQTQQQNSRKIKTQATPTLNGNGLLSGNPNGGGGDSSPSHEVDHPGGAQGAQAAGGLPSSSGTPLRHHKRASISTASPPIRERRGTNTSIVVELDGSGSG-------------------------------------------------------------------------------------------------------SGSGGGGVGVGQGAGCPPSGSCTASGKSSRELSPSPKNQQQPRKMSQDYRSRAGSFMHLDDEGRS-------LLMRKPMRLKNIEGRPEVYDTLHCKGREILSCSKATCTSSIMN----IGNAAVEARKSDLILEHAKDFLEQYFTSIKRTSSTAHETRWKQVRQSIETTGHYQLTETELIYGAKLAWRNSSRCIGRIQWSKLQVFDCRYVTTTSGMFEAICNHIKYATNKGNLRSAITIFPQRTDAKHDYRIWNNQLISYAGYKQADGKIIGDPMNVEFTEVCTKLGWKSKGSEWDILPLVVSANGHDPDYFDYPPELILEVPLTHPKFEWFSDLGLRWYALPAVSSMLFDVGGIQFTATTFSGWYMSTEIGSRNLCDTNRRNMLETVALKMQLDTRTPTSLWKDKAVVEMNIAVLHSYQSRNVTIVDHHTASESFMKHFENESKLRNGCPADWIWIVPPLSGSITPVFHQEMALYYLKPSFEYQDPAWRTHVWKKGRGESKGKKPRRKFNFKQIARAVKFTSKLFGRALSKRIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYCMSDYDISSIEHEALLIVVASTFGNGDPPENGELFSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRGSTSDTFTEETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGELGGERLLRVAYGDEMCGQEQSFRKWAPEVFKLACETFCLDPEE--SLSDASLALQNDSLTVNTVRLVPSANKGSLDSSLSKYHNKKVHCCKAKAKPHNLTRLSEGAKTTMLLEICAPG----LEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDEVLQLQLLKEKQTSNGIFKCWEPHDKIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKERLELLVNDSSAYEDWRHWRLPHLLDVLEEFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLTVAIVKYRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALGFHLPSDRSRPIILIGPGTGIAPFRSFWQEFQVLSDLDPTAKLPKMWLFFGCRNRDVD-LYAEEKAELQKDQILDRVFLALSREQAIPKTYVQDLIEQEFDS-LYQLIVQERGHIYVCGDVTMAEHVYQTIRKCIAGKEQKSEAEVETFLLTLRDESRYHEDIFGITLRTAEIHTKSRATARIRMASQP------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* *:* .. * * .*:: . :: * :*::**: *:* : * . : .: :. *.* ** :.:* ****:.**:*****.:**:**.* :: ** :* *: *:** **:*****:***: *:*:** **: ****: **. **. :::*::* . **.. ..:*::**::.* . *: * * :::***.: ** :** * *:**.:***:.**:::**::*.. .*.****.:*** *: ** * *:** *. * *: :. :*****:* . :* **::*:* :*** ***:*: **:::::.* : *.***.** *:***:***:***:***: * *.* : ** .* : . : : ..* :: *: .::.*:: *:*:.:***:: * * :: **:.: .*..* :* * *::**:******: * ** : * : *: **.*** **.****.: :* : .**..:: ***: **:::* ** .*: **: * : . :: . * * : : : : : *:::.: . .: **:*:*: * * ** ::.:: . . : :: *. * . ::*. :: : : ::*:*:**: * :: .. . .::.* * . *. *: * :::***:*** .: ::*:*:. *:** **:**: . *:***:::: *: ..* * :.*.**.:: : . : *:: .*::* : . * :*:*.*:******.***: . . * *.**** . * :* : . :: : . ** ** ****::. :: : . **:::**.: ** * ::: . . . :. : :: :.******** ", "identical_positions": 311, "similar_positions": 315, "identity": "20.89%" }, { "cls_id": "homologset.agr.FB:FBgn0011692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJ20-1", "uniprot_id": "A0A8I6GJ20_RAT", "id": "A0A8I6GJ20-1", "name": "Kinesin-like protein KIF23", "aln": "MRRAGAHLGLQRRRRALFRLSPGPRGRSLHGLVPASPAPVGARRPARASGQHGDCGHEVGAKMPRKPV----IKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVVNSTTVQLHTPEGYRLNR---NGDYKETQYSFKRVFGTHTTQKELFDVVASPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRFVFKSNDRNSMEIQCEVDALLERQKRE--AMP-IPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYLYDLLEEVQFDPIKPKL---------------PQSKMLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQMYGTN----KMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARP-VDKAICGLTPGRRYRN-----------LPRAGPVGDE-PLT-EEILQSFPPLPPCKLLDVNDEETLPRLMDALEKRHRLRQLMTEELNKQCVAFKALFKEFDNSLSNKENYIQE---KLNEKEKVISGQKSEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQHQKLQREFSDKRRLEARLQGMVTETTMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPE--KPERPSRDRDREKIIQRSVSPSPVPLSSN-NIAQISNGQQLMSQPQLHRRSNSCS---SISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKACMVSDRRRGMCWTEGREMVPTFSSEIGVQEDHCRR--------NTPIPVRHRRSRSAG-SRWVDHKPASNVQTETVMQPHVPHAITVSVA---NEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQESPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5G3-1", "uniprot_id": "KIF23_MOUSE", "id": "E9Q5G3-1", "name": "Kinesin-like protein KIF23", "aln": "-------------------------------------------------------MKSAKAKTVRKPV----IKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVINSTTLQLHTPEGYRLNR---NGDYKETQYSFKRVFGTHTTQKELFDVVANPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRYVFKSNDRNSMEIQCEVDALLERQKRE--ALP-IPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVQFDPIKPKL---------------PQSKTLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQTYGTN----KMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARP-VDKVICGLTPGRRYRN-----------LPRGGPVGDE-PLVPEVILQSFPPLPPCKLLDINDEETLPKLADTLEKRHHLRQLMTEDLNKKCLAFKALLKEFDNSLSNKENYVQE---KLNEREKVISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQNQKLQRQFSDKRRLEARLQGMVTETSMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPE--KPERPSRERDREKIIPRSVSPSPLPLSSN-NIAQISNGQQLMSQPQLHRRSNSCS---SISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKTCIVSDRRRGMCWTEGREMVPTFSSEIGVEEDHCRR--------NTPIPVRHRRSRSAG-SRWVDHKPASNVQTETVMQPHVPHAITVSVA---NEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQELPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02241-1", "uniprot_id": "KIF23_HUMAN", "id": "Q02241-1", "name": "Kinesin-like protein KIF23", "aln": "-------------------------------------------------------MKSARAKTPRKPT----VKKGSQTNLKDPVGVYCRVRPLGFPDQECCIEVINNTTVQLHTPEGYRLNR---NGDYKETQYSFKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPRCLDMIFNSIGSFQAKRYVFKSNDRNSMDIQCEVDALLERQKRE--AMP-NPKTSSSKRQVDPEFADMITVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVPFDPIKPKP---------------PQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTN----KMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARP-VDKAICGLTPGRRYRN-----------QPR-GPVGNE-PLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQSNAFKALLQEFDNAVLSKENHMQG---KLNEKEKMISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELETQNQKLQRQFSDKRRLEARLQGMVTETTMKWEKECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTE--KPERPSRERDREKVTQRSVSPSPVPLSSN-YIAQISNGQQLMSQPQLHRRSNSCS---SISVASCISEWEQKIPTYNTPLKVTSIARRRQQEPGQSKTCIVSDRRRGMYWTEGREVVPTFRNEIEIEEDHCGRLLFQPDQNAPPIRLRHRRSRSAG-DRWVDHKPASNMQTETVMQPHVPHAITVSVA---NEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPNGSRKRRSSTVAPAQPDGAESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLX5-1", "uniprot_id": "A0A8M9PLX5_DANRE", "id": "A0A8M9PLX5-1", "name": "Kinesin-like protein", "aln": "------------------------------------------------------MIRQAKGKTPRRPP----PKKPS-NNQKDPVGVYCRVRPLGAEDEECCIEVISNTTIQLHAPDGLKANR---NGEFKETQYSFKKVFGIKTTQRELFEDVAKPLAQDLIHGKNGLLFTYGVTGSGKTHTMTGSPGQGGLLPRSLDMIFNSIGPYQAKRYVFKPDDKNGMEVQNQVDALLDRQKRD--SQTSVPKTPNTRR-VDPEFADMISPEEACKAEGVDEDSSYSVFVSYIEIYNNYIYDLLEETPFDPIKPKWNGAGTPVRNITEFIPPQSKILREDQNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTQLNRESSRSHSVFIVKLAQAPLDADGDNVLQDKNQVNVSQLCLVDLAGSERTSRTRAEGNRLREAGNINQSLMTLRTCIEVLRENQMCGTN----KMVPYRDSKVTHLFKNYFDGEGKVRMVVCVNPKADDYEETLLVMRFAEMTQEVEVARP-VDRPICGFAAGRRQRNQAFKEELTRRLEERGGPVDGDCPTVLNQLLQAFPPLPPCEISGPNDDVTLPRLIEALEKRHKIRQMMIEEYNKTATMLKSVLQEQDGNILSKENVIQEQRGKLGEKDKMLQNQKNEIDRLEKKSKMLEYKIDILQKTTNIYEEDKRSLQNELESREQRLQREMSEKRRIEARMQGMVSDTKLKWEKECERRVNAKQLEMQNKLWVKDEKLKQLKAIVTEGKTENRQPQRPSREKDK-VPPKRSASPSPAPSSYNGSQSSLSSLEPIYNFSQTVRPDTHFPRAGSVSVASCISEWEQGVP-QSRRQGSQSPPDCRNRTQGLPDS---LSRRRGRCWAR---EVPVQPADVDLEETVHWT--------GPPVRPLHRRSHSAGGERWVDHKPTTNVDLDTVMQPNIPNAIKVNAP---NEKALSKCDKYVLTHQEVASDGEIQTKLIKGEVFKTRGGGQSVQFTDIETLKQETPVAASRKRRSSESGPDSEPMEGNWTDVETRCSVAVEMRAGSNLGPGYQHHGYTKRRKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZF5-1", "uniprot_id": "Q9VZF5_DROME", "id": "Q9VZF5-1", "name": "Kinesin-like protein", "aln": "------------------------------------------------MKAVPRTPMRVVPKTPRVHQTVEKQRRDTSDKARDPVNVFCRVRPLQSDADLTSLRVKNSTTIALNPQDQLLQHHKPHNGAQREVQYIFKHVFQPDATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLRHRGIMPRCLDVLFRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIASQAS-VEPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKT-------------------LQSKIIREDANRHMFVHGVTEVEVKTVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQNITVSQLSLVDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGLAPKKVPYRDSKITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQIARATPMKQDLGLTPGRRKANKLFKIAVNN-LNELGIPEAKDLEVDVGLVYSLGPDFPAYEMDSPEAQIKIRELMHYLEQRIEKRKKLRANLDIKCDSFRQMLMNLD-----RDNLQLR--TELASLKAVYKQERDRSAALEKKVRIHESSIDVLNNTLSKQERQIEELTFKLNEKENMLTQKEHEKEKQKKKFSSKLAVESDKNKREFELKLREQRVKLQERMRIKDEKLRLVSNILQ------------------------SEDLPSLPRSQS--------SENILN--------------------------EKDRGAYTARTEESSVPATR--------TDIYATPRHG----------------------------------AAAANNRHRRSRSAG-DKWLEHRAANPVPLGTIMQPYLKNRKSVTKLTDLKELTAHGTTKYCLVSQDADTDGDVETKLYKGNVIPTCGGGAQVVFNDVECLKQKSPVHSPTRKRPS------NGNISALGGGAVPSTVTSAQDVASRCNLGIEGHSSKKSKI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :: : : :***.*:****** : .:.* ..**: *:. : :: ** :*.** **:** .:**:::: **.**.::*::*:*.*************:****. *::**.*:::*.:*. :***::***.:. *.::: : ****:**:. . : . :: ***:*. . * :***. *.***:******* :*****: :: *** :*** *::*:* * ******:.*:*:*** ***::*:.:* ** ********* ::*.*** *::*:**:*:::::.:***.*********:.**: * *********:********:: ***** .:* * *******:**:*********:* *:**:**: :**:*.: **:***:****::**. : *::.*** * * : : . * :*. :: . : : .: .* . **:* . *: : : : . :: :: : * ::* :* . . : . :: . **** : * .*::*::* . *.: ..* :*: :.: * :: :*.: : ::.. :: . * ::* * :: ::::*::: :*****: :. *: * . .. * * . : : . *: . * . * : *:* .. ****:*** .:*::*:.:. : *:*** : : .*. :* : ** *. *: :**:::**: **:: * *** .* *.*:* ***: * : :: .: : . . . .:*: ..*. . * : *. * : ", "identical_positions": 306, "similar_positions": 277, "identity": "28.57%" }, { "cls_id": "homologset.agr.FB:FBgn0011693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08699-1", "uniprot_id": "PGDH_RAT", "id": "O08699-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-----------------MHVNGKVALVTGAAQGIGKAFTEALLLHG-AKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCC1-1", "uniprot_id": "PGDH_MOUSE", "id": "Q8VCC1-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-----------------MHVNGKVALVTGAAQGIGKAFAEALLLHG-AKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILESIEKEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKITASKGIHFQDYDISPLLVKAPLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15428-1", "uniprot_id": "PGDH_HUMAN", "id": "P15428-1", "name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "aln": "-----------------MHVNGKVALVTGAAQGIGRAFAEALLLKG-AKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV42-1", "uniprot_id": "Q9VV42_DROME", "id": "Q9VV42-1", "name": "Fat body protein 2", "aln": "MKPQGIPPTTTRISQTKMSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIID--LQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEK---IIFPETSDETYRILDRLNKQSAADVSRCILNVLEKDK-NGAVYVIEGKRVYPLEIKPQWTGKEQAL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..** *:***.* *** .:: ** * ****::* *: .:: . * . .*..:::: ***::: :. *:.::.. **.:**:** **: *:*: ::** :** .:*..* .* **.*:***:***::*:**:.** *: *** *:* **:.***. * .**::: .:*** . * :: .: :: : * .*. ::. . .. ::. ::.::*.* ***: * .: :: . :: ", "identical_positions": 83, "similar_positions": 99, "identity": "28.92%" }, { "cls_id": "homologset.agr.FB:FBgn0011701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BQY4-1", "uniprot_id": "RHXF2_HUMAN", "id": "Q9BQY4-1", "name": "Rhox homeobox family member 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEPPDQCSQYMTSLLSPAVDDEKELQDMNA-------------MVLSLTEEVK-----------------EEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGS--DGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQP----------NVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQ----RALMARNMLPFMAVG------------------------------QPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAG--------QAEFGPFPFVIVPSFTFPNV----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C7M4-1", "uniprot_id": "RHF2B_HUMAN", "id": "P0C7M4-1", "name": "Rhox homeobox family member 2B", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEPPDQCSQYMTSLLSPAVDDEKELQDMNA-------------MVLSLTEEVK-----------------EEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGNLEGTSGS--DGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQP----------NVHAFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQ----RALMARNMLPFMAVG------------------------------QPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAG--------QAEFGPFPFVIVPSFTFPNV----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M524-1", "uniprot_id": "F1M524_RAT", "id": "F1M524-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------MAQRVSFDHNYYFMECEEETNAGVQARA-------------VASTSTMEASGAMAVAQAGAACRSHASRGTIGYDTVYEPNVKGDPKQESESDTEESYDDEDDDEDEGDEDDLSTSDQDTSDPEQEEA---ALFVAAAAPPIAPAAAAIQIPGPHRSR--RRRHRR------HRRSSPYLFTQWQVEEMENLFEETPYPDVLTRGELARTLNVPEVKVKVWFSNRRAKQRKNE----RRAMLRNMPSGA---------------------------------EDFIFMTDVEEPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YCR7-1", "uniprot_id": "RHX13_MOUSE", "id": "F6YCR7-1", "name": "Homeobox protein Rhox13", "aln": "----------------------------------------------------------------------------------------------------------------------------------MAHGVPFDHNYYIVECKEETNAEAQAGA-------------MAATSTEEAPGAVEVAQAAVAS-SHDSGGAIGCATVKES--ESDSESESDSESES---DSSDSSDESD-DDSSTSDEDTSDPEEAAAPSVAAVAAAAAPPTVPAAAAIQIPGPYRYRPPRRHVRR------RRRGPPFHFAQWQVEEMESLFEETQYPDLLTRGELARTLNVPEVKVKVWFTNRRAKQRKIE----RREMLRNIPPGA---------------------------------EDFIFITDFEEPS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N693-1", "uniprot_id": "ESX1_HUMAN", "id": "Q8N693-1", "name": "Homeobox protein ESX1", "aln": "--------------------------------------------------------------------------------------------------------------------------------MESLRGYTHSDIGYRSLAVGEDIEEVNDEK-------------LTVTSLMARG------------------GEDEENTRS--KPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPE----RKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQ----RVLMLRNTATADLAHP-----------LDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA--------PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NHV9-1", "uniprot_id": "RHXF1_HUMAN", "id": "Q8NHV9-1", "name": "Rhox homeobox family member 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------MARSLVHDTVFY-CLSVYQVKISPTPQL-------------GAASSAEGHV------------------GQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEG----GGGNQEPRQQPQPPP--------------------EEPAQAAMEGPQP-------ENMQP--------RTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQ----RELMLANELRAD-------------------------------PDDCVYIVVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KSE4-1", "uniprot_id": "Q7KSE4_DROME", "id": "Q7KSE4-1", "name": "", "aln": "MEHDSFDDPIFGEFGGGPLNPLGAKPLMPTTTAMHPVMLGSVHELCSQQQQQQQQQRLPDCNTILPNGGGGGAGSGGAGGSPNYVTKLDFVNKMGCYSPSQKYEYISAPQKLVEQQQQQQHHHQHHQHYTATPPPSHNGILLHKQSSQQQQQQQQQLVGILDYHPLNGKLDYSSSPKDQYEPQQLQHLYGGSPHHLDHLDHGSDGLLQDSSPVMINGGSAGGKLKKPDEMCSQLEAGGAGVTPPSSSSTVVNGTTNGTGNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTTTVTPPGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTAQQQQLADGTLVTVHAHQQQQQQQQQLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQGQHYVTTATGGAASAGGTSSDDNDSGGMQTVIKSEEVSQQQQQQQGQSYVLPPFLH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . . . . : *: *::*:* * . :*. * .** :.:.* *::** *:**: :: : : . . ", "identical_positions": 16, "similar_positions": 31, "identity": "2.61%" }, { "cls_id": "homologset.agr.FB:FBgn0011703", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Q5-1", "uniprot_id": "Q5U2Q5_RAT", "id": "Q5U2Q5-1", "name": "Ribonucleoside-diphosphate reductase", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLEIVMAHKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTPEH-----TYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPEDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-------------------------------------LKDKEKAL--KEEEEKER-----------------------------------------------------NTAAMVCSLENREECLMCGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07742-1", "uniprot_id": "RIR1_MOUSE", "id": "P07742-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTPEH-----TYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDWKPLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-------------------------------------LKDKEKAL--KEEEEKER-----------------------------------------------------NTAAMVCSLENREECLMCGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23921-1", "uniprot_id": "RIR1_HUMAN", "id": "P23921-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEH-----TYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEK-------------------------------------LKDKEKVS--KEEEEKER-----------------------------------------------------NTAAMVCSLENRDECLMCGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79732-1", "uniprot_id": "RIR1_DANRE", "id": "P79732-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "-----------MHVIKRDGGQEGVMFDKITSRIQKLCYGLNSDFVDPTQITMKVIQGLYSGVTTVELDTLAAETAATSTTKHPDYAILAARIAVSNLHKETKKVFSEVMEDLYNYVNPLNSRHSPMISKETLDIVLANKDRLNSAIIYDRDFSYNFFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIAAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLAMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGRYIAGTNGNSNGLVPMLRVNNNTARYVDQGGNKRPGAFAMYLEPWHFDIFDFLELKKNTGKEEQRARDLFYALWIPDLFMKRVETNGDWSLMCPNDCPGLDECWGEEFEKLYAKYEQEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSNRQNLGTIKCSNLCTEIVEYTSADEVAVCNLASIALNMYVTSER-----TFDFQKLASVTKVIVKNLNKIIDINYYPVKEAENSNKRHRPIGIGVQGLADAFILMRFPFESTEAQLLNTQIFETIYYAALESSCELAAEYGPYQTYAGCPVSKGILQYDMWEKTPTDLWDWAALKEKIANDGVRNSLLLAPMPTASTAQILGNNESIEPYTSNIYHRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIAQNGSIQTIPAIPDDLKELYKTVWEISQKTILKMAADRGAYIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTKPGANPIQFTLNKEK-------------------------------------LKETQKTTSSEDEETKER-----------------------------------------------------NKAAMVCSLENRHECLMCGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48591-1", "uniprot_id": "RIR1_DROME", "id": "P48591-1", "name": "Ribonucleoside-diphosphate reductase large subunit", "aln": "MLKNKSMKTSKLYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFVTPEK-----TYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVSMN------------------------------GQNGTAEGSPQKYEEDRER-----------------------------------------------------KMADMVCSLENKDACMSCGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21524-1", "uniprot_id": "RIR1_YEAST", "id": "P21524-1", "name": "Ribonucleoside-diphosphate reductase large chain 1", "aln": "-----------MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDVYNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHGRDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECALISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALYLEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLSDCYGDEFEALYTRYEKEGRG-KTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNLGVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIETSEDGKTSTYNFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDSEEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDWDTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVYIDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVADISNLKRPSYMPSSASYAASDFVPAAVTANATIPSLDSSSEASREASPAPTGSHSLTKGMAELNVQESKVEVPEVPAPTKNEEKAAPIVDDEETEFDIYNSKVIACAIDNPEACEMCSG", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P21672-1", "uniprot_id": "RIR3_YEAST", "id": "P21672-1", "name": "Ribonucleoside-diphosphate reductase large chain 2", "aln": "-----------MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLDDVWGDEFEELYTRYEREGRG-KTIKAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEVSEDGKTASYNFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFESEEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDWETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYIDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQEVADQAATHIASVSELDRPVYVPKGTKFSE----------QKAASALTESSDNEKDASPVPSEQSSVSSAMSNVKLEDS--VAPAVPTETIKE-------DSDEKKCDIYNEKVIACTAPTPEACESCSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* **** :* * *****:** :*.*.*: . :*.. :* ::*.*:* **** ***.**** .* * ***** ******:*****:*.* **.*.***: :* ..: *:::. ::* : ***:*:***** *.:************: **::******::***::*** ** :.::****:* ::********* *.* :**:*****::*. ******:.::::**:***:***:*: : **:.* *.****.****:**:** **.********.*******::***** *:*:*::::*. **** ****** ************: : *:*:.* .*** : :*:*** ** **::** :.:***.**::*:::*.***.*::::**:****:*::*:*.**.**** *****:: ** *******:** :: .. :::*::* .::*::.:***::** ****: ** ** :***:.:*:**:**: :::* *::* ** ** *******:.::*:**:** * *.*: *.*.*:****:***: * .:*** *::.* *:**** :********:**:* **.:** *:*:* *********:** :**:**.: .:*.: **: :*: .**** : :* .:::********* *: ::***:*. :****:*:*:.: *. **:**:***.** ***********:..: .****:::: : . : :: : :.*: . . * *..", "identical_positions": 418, "similar_positions": 237, "identity": "46.44%" }, { "cls_id": "homologset.agr.FB:FBgn0011704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PEE3-1", "uniprot_id": "RIR2B_MOUSE", "id": "Q6PEE3-1", "name": "Ribonucleoside-diphosphate reductase subunit M2 B", "aln": "------------------------------MGDPERPEAARP-------EKGEQ------LCSETEENVVRSNE------EPLLRKSSRRFVIFPIQYPDIWRMYKQAQASFWTAEEVDLSKDLPHWN-KLKSDEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEDRVREIIADAVQIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDN---VFTLDADF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADQ1-1", "uniprot_id": "D4ADQ1_RAT", "id": "D4ADQ1-1", "name": "ribonucleoside-diphosphate reductase", "aln": "------------------------------MGDPERPEAARP-------EEGEQ------LCPETKENEVRSNE------EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWN-KLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVMEIIVDAVKIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDN---VFTLDADF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7LG56-1", "uniprot_id": "RIR2B_HUMAN", "id": "Q7LG56-1", "name": "Ribonucleoside-diphosphate reductase subunit M2 B", "aln": "------------------------------MGDPERPEAAGL-------DQDER------SSSDTNESEIKSNE------EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWN-KLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDN---VFTLDADF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11157-1", "uniprot_id": "RIR2_MOUSE", "id": "P11157-1", "name": "Ribonucleoside-diphosphate reductase subunit M2", "aln": "----MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARR------IFQDSAELESKAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE-ALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTEN---SFTLDADF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLN6-1", "uniprot_id": "RIR2_RAT", "id": "Q4KLN6-1", "name": "Ribonucleoside-diphosphate reductase subunit M2", "aln": "----MLSVRAPLATIADQQQLHLSPLKRLSLADKENTPPTLSSARVLASKAARR------IFQDSAELESKAPTKPSIEEEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE-ALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEQRVKEIITNSVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFKVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTEN---SFTLDADF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31350-1", "uniprot_id": "RIR2_HUMAN", "id": "P31350-1", "name": "Ribonucleoside-diphosphate reductase subunit M2", "aln": "----MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARR------IFQEPTEPKTKAAA-PGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE-SLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTEN---SFTLDADF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79733-1", "uniprot_id": "RIR2_DANRE", "id": "P79733-1", "name": "Ribonucleoside-diphosphate reductase subunit M2", "aln": "----MSSTRSPLKTKNE--NTISTKMNNMSFVDKENTPPSLSSTRILASKTARK------IFDE-SEGQSKAKK-GAVEEEPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWD-SLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSGTTDN---TFTLDADF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48592-1", "uniprot_id": "RIR2_DROME", "id": "P48592-1", "name": "Ribonucleoside-diphosphate reductase subunit M2", "aln": "-------MASKENIADNMEKFSLKSPSKKILTDSTNNVRKMSIGHEANGQLAKESSTVNGIGKSANSLMEKSVTPFDPSLEPLLRENPRRFVIFPIQYHDIWQMYKKAEASFWTVEEVDLSKDLTDWH-RLKDDERHFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENVHSEMYSVLIDTYIRDPHQREYLFNAIETMPAVKRKADWALSWISSKSANFGERIIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFAVLMFQHLVQRPKRERIIEIIRDAVAIEQEFLTDALPVNLIGMNCDLMSQYIEFVADRLLVELGVGKIYNTKNPFNFMEMISLDGKTNFFEKKVGEYQRMGVVSNPLDN---VFTLDADF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7ZYW0-1", "uniprot_id": "Q7ZYW0_DANRE", "id": "Q7ZYW0-1", "name": "", "aln": "------------------------------MNSCTSNTPTVITGYQNG---------------------HKDVDPNSVEDEPLLRENPKRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLTHWD-GLKSEEKHFISHVLAFFAASDGIVNENLVQRFSQEVQLPEARSFYGFQILIENVHSEMYSMLINTYIRDLKERDYLFNAVQTMPCVRRKADWALQWISDTNSTFGERLVAFAAVEGIFFSGSFAAIYWLKKRGLMPGLTYSNELISRDEGLHCNFACLIYSYLVKKPSVDRVNDIIAKAVSIEQEFLTEALPVNLIGMNCSLMKQYIEFVADRLLTDLGLPKAYCSENPFDFMESISLEGKTNFFEKRVAEYQRLGVMSNVKDC---EFTLDADF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09938-1", "uniprot_id": "RIR2_YEAST", "id": "P09938-1", "name": "Ribonucleoside-diphosphate reductase small chain 1", "aln": "MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAEN-----HKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P49723-1", "uniprot_id": "RIR4_YEAST", "id": "P49723-1", "name": "Ribonucleoside-diphosphate reductase small chain 2", "aln": "------------------------------MEAHNQFLKTFQ--------------------------KERHDMKEAEKDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEEIELAKDTEDFQ-KLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQIMMENIYSEVYSMMVDAFFKDPKN-IPLFKEIANLPEVKHKAAFIERWISNDDSLYAERLVAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAGKTTFFEKKVSDYQKASDMSKSATP-SKEINFDDDF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ** :. .* *:***:* :** **:.:*****.**::*:** .:. :. ::: :*..:**: :**.:**: *::.*: ::* .*.:.****** :**::** **::::::::* :: **: : .:* : .** : ** . .: :.**::***: **:* :*.:*:::**..: :****: :*. *.**.* : :*: *:: :* :* : .*: .:* **:.: ::*** :**: : *:***** *: :* * : ***:*** :: ***.****:*.:**: . :: :.:: **", "identical_positions": 115, "similar_positions": 124, "identity": "28.47%" }, { "cls_id": "homologset.agr.FB:FBgn0011708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08851-1", "uniprot_id": "STX5_RAT", "id": "Q08851-1", "name": "Syntaxin-5", "aln": "MIPRKR--------YGSKNT------DQG---------------------------------VYLGL-------------------------------------------------------SKTQVLSPATAINSSSDIAPLPTPVALVPS-PPDTMSCRDRTQEFLSACKSLQSR--QNGIQTNKP-ALHATRQCSEFTLMARRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVR-------AKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRNRREQFSRAP--VSALPLAPN-------NLGGGPIVLGGESRASRDVAIDMMDPRTS------QQLQLIDE----QDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1E0-1", "uniprot_id": "STX5_MOUSE", "id": "Q8K1E0-1", "name": "Syntaxin-5", "aln": "MIPRKR--------YGSKNT------DQG---------------------------------VYLGL-------------------------------------------------------SKTQVLSPATAISSSSDSTPLPTPVALVPS-PPDTMSCRDRTQEFQSACKSLQSR--QNGIQTSKP-ALHAARQCSEFTLMARRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVR-------AKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRNRREQFSRAP--VSALPLAPN-------NLGGGPIILGAESRASRDVAIDMMDPRTS------QQLQLIDE----QDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13190-1", "uniprot_id": "STX5_HUMAN", "id": "Q13190-1", "name": "Syntaxin-5", "aln": "MIPRKR--------YGSKNT------DQG---------------------------------VYLGL-------------------------------------------------------SKTQVLSPATAGSSSSDIAPLPPPVTLVPP-PPDTMSCRDRTQEFLSACKSLQTR--QNGIQTNKP-ALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVR-------AKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAP--VSALPLAPN-------HLGGGAVVLGAESHASKDVAIDMMDSRTS------QQLQLIDE----QDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PD64-1", "uniprot_id": "A0A8M1PD64_DANRE", "id": "A0A8M1PD64-1", "name": "", "aln": "MNTRRR--------HGPKSS------QDG---------------------------------VYTGP-------------------------------------------------------SQTQSQLVQQLETP----LAVPAPIAPVP--DTFSMSCRDRTGEFQSVCKSLQGR--QNGAQPVRA-VNNAIQKRSDFTLLAKRIGRDLSNTFAKLEKLTILAKRKSLFDDKATEIDELTYIVKQDINSLIKQIAGLQELVR-------SRSAQNGRHLQTHSNTIVVSLQSKLASMSSDFKSVLEVRTENLKQQRSRQEQFSQTP--ASASAFHTN-------SFNN-SVLMQDDSKKT-DISID-MDLNSS------QQMQLVNE----RDSYIQNRADTMQNIESTIVELGSIFQQLAHMVKEQEETVHRIDANVEDTQLNVDLAHTEILKYFQSVSNNRWLLIKMFLVLVIFFIVFVLFMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24509-1", "uniprot_id": "STX5_DROME", "id": "Q24509-1", "name": "Syntaxin-5", "aln": "MQTRRRLHQTDQQDYSSSSTYTIQEDQQGGAGAGSVGTGTAGGSVGLLAQSLVPPPTGHEAAIHIGDNYQSGDSISTPDYSDDKYGKAARQWNLRAFSGHALRTLSAAAAVVTGNQPGINNDSQSNYSYPASIPTSSQFYQSKEEPQETEPEPEIFVMAARDRTGEFANAIRSLQARNITRAVNIRDPRKAKQVQSYSEFMMVARFIGKNIASTYAKLEKLTMLAKKKSLFDDRPQEIQELTYIIKGDLNALNQQIARLQDISKD------QRRHTNGKHLVSHSSNMVLALQSKLASMSTDFKQILEVRTENLKQQKTRRDQFSQGPGPLAAHTVSPS-------TAKQGSLLLSEE---NQAVSIDMGSSDTTPLLSTQTQMAIYDD----SDNYVQQRAETMQNIESTIVELGGIFQQLAHMVKEQEEIVERIDTNVADAELNIEAAHGEILKYFQSVSKNRWLMIKIFGVLIFFFLFFVVFMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01590-1", "uniprot_id": "SED5_YEAST", "id": "Q01590-1", "name": "Integral membrane protein SED5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MNIKDRTSEFQQSVLSYKKRNKNFREQQRERLQE--KESENFANN-TTGNGKSVSEFQKKASGIAHEISSTAQLLSKLAVLAKRKPMFNDNPVEIAELSFLIKRKIYAIEQSLVQLSQLKKTDVNGNTSNQSSKQPSAVQHSKNVVNLLNTQMKNISGSFKDVLEERQRLEMANKDRWQKLTTDTGHAPADDQTQSNHAADLTTYNNSNPFMTSLLDESSEKNNNSSNQGELSFPQNDSQLMLMEEGQLSNNVYLQERNRAVETIESTIQEVGNLFQQLASMVQEQGEVIQRIDANVDDIDLNISGAQRELLKYFDRIKSNRWLAAKVFFIIFVFFVIWVLVN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :.*. :* . :. . .. : :. *:* * *.::::.* *.**::***:*.:*:*.. ** **::::* .: :: :.:. *.:: : . . **..:* *:::: .:* .**.:** * . :: * :::: . .* . .: . : . *: : :: : *:*.* :::.***** *:*.:***** **:** * :.*** ** . :*::. *: *:****: :..**** *:* ::..**:.:*:. ", "identical_positions": 76, "similar_positions": 115, "identity": "15.61%" }, { "cls_id": "homologset.agr.FB:FBgn0011710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42208-1", "uniprot_id": "SEPT2_MOUSE", "id": "P42208-1", "name": "Septin-2", "aln": "----------------------------------------------------------------------------------MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTD--------LYPERIIPGAAEK-------------IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINC-RDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAK-GKKVRGRLYPWGVVEVENPEHNDFLKLRTMLIT-HMQDLQEVTQDLHYENFRSERLKR------GGRKVENED------------------------------MNKDQILLEKEAELR-RMQEMIARMQAQMQMQMQGGDSDSGALGQHV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15019-1", "uniprot_id": "SEPT2_HUMAN", "id": "Q15019-1", "name": "Septin-2", "aln": "----------------------------------------------------------------------------------MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTD--------LYPERVIPGAAEK-------------IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINC-RDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAK-GKKVRGRLYPWGVVEVENPEHNDFLKLRTMLIT-HMQDLQEVTQDLHYENFRSERLKR------GGRKVENED------------------------------MNKDQILLEKEAELR-RMQEMIARMQAQMQMQMQGGDGDGGALGHHV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91Y81-1", "uniprot_id": "SEPT2_RAT", "id": "Q91Y81-1", "name": "Septin-2", "aln": "----------------------------------------------------------------------------------MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTD--------LYPERIIPGAAEK-------------IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINS-RDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAK-GKKVRGRLYPWGVVEVENPEHNDFLKLRTMLIT-HMQDLQEVTQDLHYENFRSERLKR------GGRKVENED------------------------------MNKDQILLEKEAELR-RMQEMIARMQAQMQMQMQGGDTDSSTLGHHV-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BJN0-1", "uniprot_id": "A0A8M2BJN0_DANRE", "id": "A0A8M2BJN0-1", "name": "", "aln": "----------------------------------------------------------------------------------MS-QTGEKGKFPDAAGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTD--------LYPERYIPGAAEK-------------IERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINS-QDCFKTIIQYIDNQFERYLHDESGLNRRHIVDNRVHCCFYFISPFGHGLKPLDVEFMKAIHSKVNIVPVIAKADTLTLKERDRLKRRILDEISEHGIRIYQLPDADSDEDEEFKEQTRVLKASIPFAVIGSNQLIEVK-GKKIRGRLYPWGVVEVENPEHNDFLKLRTMLVT-HMQDLQEVTQDLHYENFRSERLKR------AGRAADVEDV-----------------------------MDKDQILLEKEAELR-RMQQMIAQMQAQMKMKP--GDD--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42207-1", "uniprot_id": "SEPT1_DROME", "id": "P42207-1", "name": "Septin-1", "aln": "----------------------------------------------------------------------------------MADTKG--FSSIETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTD--------LYPERIIPDAIEK-------------QKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDN-SNSFGAILEYIDEQYERFLRDESGLNRRNIVDNRIHCCFYFISPFGHGLKPLDVEFMKKLHSKVNIVPVIAKADCLTKKEILRLKCRIMQEIESHGIKIYPLPDCDSDEDEDYKEQVKQLKEAVPFAVCGANTLLEVK-GKKVRGRLYPWGVVEVENPDHCDFIKLRTMLIT-HMQDLQEVTQEVHYENYRSDRLAKGIKGKENGVKAERDSSSQ--------------------VVSNSVLGEKDRILQEKEAELR-RMQEMLAQMQARMQAQQ-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSERFEAAESDVKVEPGLGMGITSSQSEKGQVLPDQPEIKFIRRQINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPP-IYSNDDAENSHLSERLFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNHSPVPTKKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *********:* **:*:*:**.*.*: ** .*:**:**:::** .* * *. . *: .:.*:::: ***.****.*.*:** *:** :: ..: .*:. **.:::::* *. :**: * *:*:*.*:***.* ** *****: **: ::.* *::*****:* ** :* :* *:::: . .*.:: * *::* : .. . * ::*::* *:* ::* *:::*** *****:**:* :* ** *:.:*:. .*::*:* *..: ***:**.:* : . : : :*:: * :.*:** * ::* :: ::: ", "identical_positions": 128, "similar_positions": 124, "identity": "24.57%" }, { "cls_id": "homologset.agr.FB:FBgn0011715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12824-1", "uniprot_id": "SNF5_HUMAN", "id": "Q12824-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8YH81-1", "uniprot_id": "A0A8J8YH81_RAT", "id": "A0A8J8YH81-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H3-1", "uniprot_id": "SNF5_MOUSE", "id": "Q9Z0H3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U379-1", "uniprot_id": "SNF5_DANRE", "id": "Q5U379-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MALSKTYGQKPIKFQLEEDGDFYMIG---SEVGNYLRMFRGSLYKRYPSLSRRLATVEERKKIVASSH---------DHGYTTLATSVTLLKASEVEEIFDG----HDEKYKAVSISTEPPAYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQQEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFAEILCDDLDLSPLT---FVPAIASAIRQQIESYPTDS-ILDEQM-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQRTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24090-1", "uniprot_id": "Q24090_DROME", "id": "Q24090-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAL-QTYGDKPVAFQLEEGGEYYYVG---SEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGLS-----------SHILASSVSLLRAVEVDDIMAG----NDEKYRAVSVNTSDTPVPRESK---------------------SKKQPQYVPTMPNSS-HLDAVPQATPINRNRVHTK---------------------------------------KVRTFPMCFDDTDPTASLEN----------------------------------------AAQKECLVPIRLDMELEGQK--LRDTFTWNKNESMITPEQFAEVLCDDLDLNPLP---FVPAIAQAIRQQIEAFPNDPPILEETC-----DQRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRTYAFSEA-----------------PLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18480-1", "uniprot_id": "SNF5_YEAST", "id": "P18480-1", "name": "SWI/SNF chromatin-remodeling complex subunit SNF5", "aln": "MNNQPQGTNSVPNSIGNIFSNIGTPSFNMAQIPQQLYQSLTPQQLQMIQQRHQQLLRSRLQQQQQQQQQTSPPPQTHQSPPPPPQQSQPIANQSATSTPPPPPAPHNLHPQIGQVPLAPAPINLPPQIAQLPLATQQQVLNKLRQQAIAKNNPQVVNAITVAQQQVQRQIEQQKGQQTAQTQLEQQRQLLVQQQQQQQLRNQIQRQQQQQFRHHVQIQQQQQKQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGQIPQSQQVPQVRSMSGQPPTNVQPTIGQLPQLPKLNLPKYQTIQYDPPETKLPYPTYWSDKKADTDTLLYEQIIQRDKINKYSLIRETNGYDPFSIYGFSNKEYISRLWHTLKYYQDLKNTRMKSITSTSQKIPSASIWGNGYSGYGNGITNTTTRVIPQVEVGNRKHYLEDKLKVYKQAMNETSEQLVPIRLEFDQDRDRFFLRDTLLWNKNDKLIKIEDFVDDMLRDYRFEDATREQHIDTICQSIQEQIQEFQGNPYIELNQDRLGGDDLRIRIKLDIVVGQNQLIDQFEWDISNSDNCPEEFAESMCQELELPGEFVTAIAHSIREQVHMYHKSLALLGYNFDGSAIEDDDIRSRMLPTITLDDVYRPAAESKIFTPNLLQISAAELERLDKDKDRDTRRKRRQGRSNRRGMLALSGTSASNTSMNGVHNTVAAGNASSLPPGEILLPDIADIPRTFRTPVPSTLMPGGVDVGPSVESYELRNTTTYKSRPDRPKPVSPPCYIIDHIPGHSLLLSIKLPGKVNTKEEFAAAPNDTSSGTNAMLPSPESLKTKLNSNIRAGVTIPSIPNPIANHTVTNSPNPTLQPVIPGGAASKSVPTPSLPIAPPVAPHDSEATLLTNSNNGSSNNNTQNT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06168-1", "uniprot_id": "SFH1_YEAST", "id": "Q06168-1", "name": "Chromatin structure-remodeling complex subunit SFH1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MSHQNQLIPQAYISN--FHNRLTNEDDGIPIFTMAQQTRQHKRAK--VVNYAEYDNDLFDEFNMNGSNFNNADTHYKDNAVSHENTPALTNGVTMDGSEYNVLENMNGADSIISNNKYDAG---SNMVVESLSGLNSNNNASNGPSN-----------------KAQAQDIGNAVLPDLQDQHHNPFNILRYPKIRDTFINGK---------------------------------------VVSPYRLNTDQETKANANSG-------------------------------------------EAIMIPITLDIEHMGHT--IKDQFLWNYNDDSISPEEFASIYCKDLDMTSAT---LQTQIANIIKEQLKDLENIAATEIMSD------LHVIINLTCNLQDRFFEDNFQWNLNDKSLTPERFATSIVQDLGLTREFIPLISQSLHETILKIKKDWVDGHLIQDHVPN-----DAAFGYLSGIRLDIDELG--SNWCPRVEILTKEEIQKREIEKERNLRRLKRETDRLSRRGRRRLDDLETTMRM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . :: : : : . . : . ::. . . :. * .:. . . . . :. . : *. : . :. : . ::** *::: . ::* : ** *:. :. * * . * : . *.. *::*:: . :: ::* : : : *:.:*::.:.. **.** .: :* * **:. *: *:: : : . : . . : * : :: *::: :::*: ** :* ", "identical_positions": 34, "similar_positions": 104, "identity": "3.76%" }, { "cls_id": "homologset.agr.FB:FBgn0011723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4W8-1", "uniprot_id": "D4A4W8_RAT", "id": "D4A4W8-1", "name": "T-box transcription factor T", "aln": "-------------------------------MSSPGTESAGKSLQYRVDHLLSAVESELQAGSEK------------GDPT--ERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER--------NDHKDVMEEPGDCQQPGYSQSGGWLVPGAGTLCPPASSHPQFGGSLSLPS---THGCERYP------TLRNHRSSPYPSPYAHRNNSP--TYADNSSACLSMLQSHDNWSSLGVPAHTSMLPVSHNAS---------------------------PPT-GSSQYPSLWSVSN---------GTITP-GSQTAGVSNGLGAQFFRGSPAHYAPL-THTVSAATSSSSGSPMYEGAATVTDISDSQYDT-AQSLLIASWTP-----VSPPSL---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20293-1", "uniprot_id": "TBXT_MOUSE", "id": "P20293-1", "name": "T-box transcription factor T", "aln": "-------------------------------MSSPGTESAGKSLQYRVDHLLSAVESELQAGSEK------------GDPT--ERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVTADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER--------NDHKDVMEEPGDCQQPGYSQWG-WLVPGAGTLCPPASSHPQFGGSLSLPS---THGCERYP------ALRNHRSSPYPSPYAHRNSSP--TYADNSSACLSMLQSHDNWSSLGVPGHTSMLPVSHNAS---------------------------PPT-GSSQYPSLWSVSN---------GTITP-GSQTAGVSNGLGAQFFRGSPAHYTPL-THTVSAATSSSSGSPMYEGAATVTDISDSQYDT-AQSLLIASWTP-----VSPPSM---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15178-1", "uniprot_id": "TBXT_HUMAN", "id": "O15178-1", "name": "T-box transcription factor T", "aln": "-------------------------------MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEK------------GDPT--ERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER--------SDHKEMMEEPGDSQQPGYSQWG-WLLPGTSTLCPPANPHPQFGGALSLPS---THSCDRYP------TLRSHRSSPYPSPYAHRNNSP--TYSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNAS---------------------------PPT-SSSQYPSLWSVSN---------GAVTP-GSQAAAVSNGLGAQFFRGSPAHYTPL-THPVSAP--SSSGSPLYEGAAAATDIVDSQYDAAAQGRLIASWTP-----VSPPSM---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07998-1", "uniprot_id": "TBXTA_DANRE", "id": "Q07998-1", "name": "T-box transcription factor T-A", "aln": "-------------------------------MSAS-------SPDQRLDHLLSAVESEFQKGSEK------------GDAS--ERDIKLSLEDAELWTKFKELTNEMIVTKTGRRMFPVLRASVTGLDPNAMYSVLLDFVAADNNRWKYVNGEWVPGGKPEPQSPSCVYIHPDSPNFGAHWMKAPVSFSKVKLSNKLNGGGQIMLNSLHKYEPRIHIVKVGGIQKMISSQSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKER--------SDHKEVPDHSTDNQQSGYSQLGGWFLPSNGPMGP-SSSPPQFNGAPVHSS---GSYCERYS------SLRNHRAAPYPSHYSHRSTTTN-NYMDNSSGS---LASHDSWSALQIPNSSGMGTLAHTTN---------------------------TTS-NTSQYPSLWSVAG---------TTLTPSGSASGSITGGLTSQFLRGSSMSYSGL-TSSLPVS----SPSSMYDPGLSEVGVGDAQFES-SIARLTASWAP-----VAQSY----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3Z977-1", "uniprot_id": "D3Z977_RAT", "id": "D3Z977-1", "name": "", "aln": "-----------------------------MAMSELATQ---KSGEGTVSRLLNVVESELQAGREK------------GDPT--EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLSGGGQIMLNSLHKYEPQVHIVRVGGAHRMVMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER--------NHLKEIPEAVSESQHVTYSHLGGWILSNPDGMCTTGSANYQYATPLPLPAPHTRHGCEHYA------GLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPESWTSLPSAPHGGILSVPHTSG---------------------------PINPGPSPYPCLWTISN---------GGGGPVASGSE-VHASASGTFLLGSPTVTSPS-SLLPTQATTSAGVEVLGEPSLTSIAVS--TWTAVASHPLPGWGGPGGAGRHSPSSLDS-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME7-1", "uniprot_id": "TBX19_MOUSE", "id": "Q99ME7-1", "name": "T-box transcription factor TBX19", "aln": "-------------------------------MSELATQ---KAGEGTVSRLLNVVESELQAGREK------------GDPT--EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVRTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGGAHRMVMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER--------NHLKDVPEAISESQHVTYSHLGGWILSNPDGVCTAANSNYQYATPLPLPAPHTHHGCEHYA------GLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHSNG---------------------------PINPGPSPYPCLWTISN---------GGGGPVASGSE-VHASTSGTILLGNPAVTSPS-SLLPTQATTSAGVEVLGEPSLTSIAVS--TWTAVASHPLPGWGGPGGAGRHSSSSLDS-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60806-1", "uniprot_id": "TBX19_HUMAN", "id": "O60806-1", "name": "T-box transcription factor TBX19", "aln": "-----------------------------MAMSELGTR---KPSDGTVSHLLNVVESELQAGREK------------GDPT--EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKER--------NHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYS------GLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSGPDSWTSLSSTPHASILSVPHTNG---------------------------PINPGPSPYPCLWTISN---------GAGGPSGPGPE-VHASTPGAFLLGNPAVTSPP-SVLSTQAPTSAGVEVLGEPSLTSIAVS--TWTAVASHPFAGWGGPGAGGHHSPSSLDG-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55965-1", "uniprot_id": "BYN_DROME", "id": "P55965-1", "name": "T-related protein", "aln": "MTTSHILSAVDPTTGLSGNVSGGGGGGGAGGGAGSGSPQHVTHNGHGHGHGLGGVAAVSGGGASVSGNGGHRVVGGAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKTNGNGQIMLNSLHKYEPRVHLVRVGSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVGPS--SGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTGVGVGGGAGTTGSPQAAYGAAAHQVYHPTPTSPTHQLYTNAVLNAPSALSYSASGWHNGSGAEYGLYQNAAAAYYQPEYIPLEIGYATHPLEPVDVSKTLDDPQAAMYKPSDEQGSVITLECASSSLKSSHDIKIESSSLEHAGERGTVGGGAAVVSVPTAVVNGAPAVAADTWTPLTPPQSTLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: *. * * . *... :::::: *:: ** :*:::********.*******:: ..:**** ***:.**:** *.:***********.**.* . . :*:**:********** *:**:****:** .*.*************::*:*:**. :: : . ****************:*:****:************* .. : . : . .. .. .: *::* : * :**. . . . : *. . :. ::* . .: . . . . . . **. * . : *.. : : : : : : . . . . ", "identical_positions": 134, "similar_positions": 106, "identity": "19.17%" }, { "cls_id": "homologset.agr.FB:FBgn0011725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AL98-1", "uniprot_id": "A0A8I6AL98_RAT", "id": "A0A8I6AL98-1", "name": "poly(A)-specific ribonuclease", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MCGYGFLQLLTSVAGLIG----MP--KEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------RVRSLSTSLWSLTHLTALHLNDNNLARIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNDNYLRVLPYELGRLFQLQTLGLTGNPLSQDIMSLYQDPDGTRKLLNFMLDNLAV------------HPEQLPPRPWITLKERDQILP----SASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFGTG-MKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASS--RPGSPTADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADN-HKDFKELRYNECLMNFSCSGKNGSSEGRITHGFQLKSAYENN-LMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEG6-1", "uniprot_id": "CNO6L_MOUSE", "id": "Q8VEG6-1", "name": "CCR4-NOT transcription complex subunit 6-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MRLIG----MP--KEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------RVRSLSTSLWSLTHLTALHLNDNNLARIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNDNYLRVLPYELGRLFQLQTLGLTGNPLSQDIMSLYQDPDGTRKLLNFMLDNLAV------------HPEQLPPRPWITLKERDQILP----SASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNWDADIISLQEVETEQYFTLFLPALKDRGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFGTG-MKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASS--RPGSPTADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADN-HKDFKELRYNECLMNFSCSGKNGSSEGRITHGFQLKSAYENN-LMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LI5-1", "uniprot_id": "CNO6L_HUMAN", "id": "Q96LI5-1", "name": "CCR4-NOT transcription complex subunit 6-like", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MRLIG----MP--KEKYDPPDPRRIYTIMSAEEVANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQLQTLGLKGNPLSQDILNLYQDPDGTRKLLNFMLDNLAV------------HPEQLPPRPWITLKERDQILP----SASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFGAG-MKPIHAADKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASS--RPGSPTADPNSIPLVLCADLNSLPDSGVVEYLSNGGVADN-HKDFKELRYNECLMNFSCNGKNGSSEGRITHGFQLKSAYENN-LMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHPPLLPLVNGVHLPNRR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BHJ4-1", "uniprot_id": "CNO6L_DANRE", "id": "A2BHJ4-1", "name": "CCR4-NOT transcription complex subunit 6-like", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP--KEKYDPPDPRRLYTIMSAEEVASGKKSHWTELEISG---------------------------------------------------------------------------------------------------------------------------------------RVRSLSSSLWTLTHLTALHINNNNLSRIPPEIAKLPHLVYLNLSSNKLRSLPAELGNMVTLRELLLNNNCLRVLPYELGRLFQLQTLGLKGNPLSQDILNLYQEPDGTRKLLNYMLDNLAV------------HPEQLPQRPWITLRERDQMMP----TAVFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEITNCDADIISLQEVETEQYYTFFLETLKDRGYDGFFCPKSRAKLVSEQERKHVDGCGVFFKTEKFALVQKHTVEFN--QVAMANSEGSEVMLNRVMTKDNIGVAVLLEVKKDLFATG-LKP--PPEKQLLLVANAHMHWDPEYSDVKLIQTMMFLSELKSIAERASGSINSSSPTSETSSIPIVLCADLNSLPDSGVVEYLSNGGVAEN-HKDFKELRYSDCLTNFSCNGKNGKPDGSITHSFQLKSAYEGN-LMPYTNYTYDFKGVIDYIFFSKTHMSVLGVLGPLETQWLKDNNITGCPHPHIPSDHFSLLAQLEYHPPLPPLN-GLHLPVHSTACESKMLTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K3P5-1", "uniprot_id": "CNOT6_MOUSE", "id": "Q8K3P5-1", "name": "CCR4-NOT transcription complex subunit 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP--KEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------KVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSGT-------AKRISTEQPPPRSWIMLQEPDRTRP----TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIISLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRSLK-SSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGGVETN-HKDFKELRYNESLTNFSCNGKNGMTNGRITHGFKLKSAYENG-LMPYTNYTFDFKGIIDYIFYSKPQLNTLAILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXU9-1", "uniprot_id": "CNOT6_RAT", "id": "Q6AXU9-1", "name": "CCR4-NOT transcription complex subunit 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP--KEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------KVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSGT-------AKRISTEQPPPRSWIMLQEPDRTRP----TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIISLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRSLK-SSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGGVETN-HKDFKELRYNESLTNFSCNGKNGMTNGRITHGFKLKSAYENG-LMPYTNYTFDFKGIIDYIFYSKPQLNTLAILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULM6-1", "uniprot_id": "CNOT6_HUMAN", "id": "Q9ULM6-1", "name": "CCR4-NOT transcription complex subunit 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP--KEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------KVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGT-------AKRITTEQPPPRSWIMLQEPDRTRP----TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLK-SSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETN-HKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESG-LMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA39-1", "uniprot_id": "A0AB32TA39_DANRE", "id": "A0AB32TA39-1", "name": "poly(A)-specific ribonuclease", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MMKDQKRLATCLITG----MP--KEKYDPPDPRRMYTIMSSEEAANGKKSTWAELEIVG---------------------------------------------------------------------------------------------------------------------------------------KVKSLSSALWSLTHLTALYISDNSLSRIPPDIAKLNNLVYLDLSSNKIRSLPAELGNMINLRELLLNNNQLRVLPFELGKLFQLQTLGLKGNPLAQEILNLYQEPDGTRRLLNYLLDNLAG--------TKRAPIEQPPPRSWIPLQEPDRTRP----AALFSVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLLELKEQGYEGFFSPKSRARTMSESDRKHVDGCAVFYKTDKFSLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSDVKLVQTMMFLSEVKNIVDKATRSLKLSSVSGETNAIPLVLCADLNSLPDSGVVEYLSTGGVDGA-HKDFKELRYIDSLTNFNCNGKNGTSSTRITHGFKLKSAYENG-LMPYTNYTFDFKGIIDYIFYSQPLLNVLGVLGPLEHHWLLENNVTGCPHPHIPSDHFSLFAQLELLLPFPPAVNGIHLPGRR----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMX1-1", "uniprot_id": "Q8IMX1_DROME", "id": "Q8IMX1-1", "name": "poly(A)-specific ribonuclease", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MCIFKKRDAYHQAVIMKGNHYKMSRNKDKYDSAN-RRQQIFLSQEDIAAGKKTNWSGLEITG---------------------------------------------------------------------------------------------------------------------------------------CVRNISPSLWEFEHLTALYLNDNQLLRLPADVGMLTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNNFLRVLPYEIGKLFHLVILGLMGNPLQKEFMNIYNEPNGTQKLLTYMLDNLSF------------TVNPPPQRPWLPLAKPNKTRP----ACIFTVMCYNVLCDKYATRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFN--QLAMANAEGSDNMLNRVMPKDNIGLAALLKVKENAWEPM---SEVTQISQPLLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEASHSFRPGHKN-DSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMD-HLDFKDMGYKSCLQRLLSNDTN-----EFTHSFKLASAYNED-IMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVELELMHTASQQAPPNGLINRR----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31384-1", "uniprot_id": "CCR4_YEAST", "id": "P31384-1", "name": "CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4", "aln": "MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMNQLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNNNGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQLHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAAPPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTATNSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIENRMVMPKDSKYDDQLWHALDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLEKQFLKILTEKSVTG-LIFYLRDNRPEIPLPHERRFIEINTDGEPQREYDSLQQSTEHLATDLAKRTFTVLSYNTLCQHYATPKMYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAMDFSGAWMKHKKFQRTEDYLNRAMNKDNVALFLKLQHIPS--------------GDTIWAVTTHLHWDPKFNDVKTFQVGVLLDHLETLLKEETS----HNFRQDIKKFPVLICGDFNSYINSAVYELINTGRVQIHQEGNGRDFGYMSEKN--------------FSHNLALKSSYNCIGELPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEVDPEYVS--KFIGFPNDKFPSDHIPLLARFEFMKTNTGSKKV-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : . : * : : :: * : .:*. :: .** *::..* * :*.:: * * *:** *:: *******. . *: : : * : .**:*:*.* :* *.: **** ::::.: : . * *: :: ** . : * * : * : . . *:*:.**.**::*** ::* * ***** *:**:: : ::* :*::.***:*:: : :: *.. ** *:* .*:**: : . : * **** :*:: .:* *: : ::*. : : : :: ***.* ***:.: *: . : : . .:*:****:: *** .*. :: ..::.: .. : : . :::*.*:** :*.* * :..* * . : ::: * . ::*.: * *:*: :*.**:* .*..:****::: : .:** :. .:: :. * *: :****:.*:..:* . ", "identical_positions": 135, "similar_positions": 185, "identity": "15.19%" }, { "cls_id": "homologset.agr.FB:FBgn0011726", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RC65-1", "uniprot_id": "M0RC65_RAT", "id": "M0RC65-1", "name": "", "aln": "MA-SGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETK------ESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGSVVVSLEGKPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P45591-1", "uniprot_id": "COF2_MOUSE", "id": "P45591-1", "name": "Cofilin-2", "aln": "MA-SGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETK------ESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGSVVVSLEGKPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y281-1", "uniprot_id": "COF2_HUMAN", "id": "Q9Y281-1", "name": "Cofilin-2", "aln": "MA-SGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETK------ESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18760-1", "uniprot_id": "COF1_MOUSE", "id": "P18760-1", "name": "Cofilin-1", "aln": "MA-SGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETK------ESKKEDLVFIFWAPENAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45592-1", "uniprot_id": "COF1_RAT", "id": "P45592-1", "name": "Cofilin-1", "aln": "MA-SGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETK------ESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23528-1", "uniprot_id": "COF1_HUMAN", "id": "P23528-1", "name": "Cofilin-1", "aln": "MA-SGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETK------ESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0P5-1", "uniprot_id": "DEST_MOUSE", "id": "Q9R0P5-1", "name": "Destrin", "aln": "MA-SGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIVVEEGKEILVGDVGATITDPFKHFVGMLPEKDCRYALYDASFETK------ESRKEELMFFLWAPEQAPLKSKMIYASSKDAIKKKFPGIKHEYQANGPEDLN-RTCIAEKLGGSLIVAFEGSPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7M0E3-1", "uniprot_id": "DEST_RAT", "id": "Q7M0E3-1", "name": "Destrin", "aln": "MA-SGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIVVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETK------ESRKEELMFFLWAPEQAPLKSKMIYASSKDAIKKKFPGIKHEYQANGPEDLN-RTSIAEKLGGSLIVAFEGSPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60981-1", "uniprot_id": "DEST_HUMAN", "id": "P60981-1", "name": "Destrin", "aln": "MA-SGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETK------ESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLN-RACIAEKLGGSLIVAFEGCPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03048-1", "uniprot_id": "COFI_YEAST", "id": "Q03048-1", "name": "Cofilin", "aln": "MSRSGVAVADESLTAFNDLKLG---------KKYKFILFGLNDAKTEIVVKET----------STDPSYDAFLEKLPENDCLYAIYDFEYEINGN----EGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRG------AGSH-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P45594-1", "uniprot_id": "CADF_DROME", "id": "P45594-1", "name": "Cofilin/actin-depolymerizing factor homolog", "aln": "MA-SGVTVSDVCKTTYEEIKKD---------KKHRYVIFYIRDEKQIDVETVADR-------NAEYDQFLEDIQKCGPGECRYGLFDFEYMHQCQGTSESSKKQKLFLMSWCPDTAKVKKKMLYSSSFDALKKSLVGVQKYIQATDLSEAS-REAVEEKLRATDRQ-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *** * * : ::* *: : ::* : * : : : : :* *.::* : : ..::..:.:: *.*: * ::.**:*:** **::: : *:. * . .: . : . . ", "identical_positions": 25, "similar_positions": 49, "identity": "14.45%" }, { "cls_id": "homologset.agr.FB:FBgn0011737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63802-1", "uniprot_id": "WEE1_RAT", "id": "Q63802-1", "name": "Wee1-like protein kinase", "aln": "MSFLS-RQQPPPTRRAAAACSLRQKLIFSPGSDCEEEEEEEEE-GSGHSTGEDSAFQEPDSPLPSARSPAEAEAERRRRSPGAEPSSPGELEEDLLLRGGGGGAQAAGGGAEGDSWEEEGFGSSSPVKSPTTAYFLGSSFSPVRCGGPGDASPRGCGVPRAMDDPCSPQPDYPSTPPHK-TFRKLRLFDTPHTPKSLLSKARVID---------SSSVKLRGSSLFMDTEKSGKREFDTR---QTPQVNINPFTPDPVMLHSSGQCRG-RKRAYF------------NDSS-EDMEASDYEFEDETR-PAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDDHMLIQNEYCNGGSLADAVSENYRVMSYFTEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPN----AVSEEGDEDDWIS----------NKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYSHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQELTELLKVMIHPDPERRPSAMVLVKHSVLLSA-SRKSAEQLRIELNAEKFKNSLLQKELKKAQMAAKVAAEERALLTDRMATRSTTQSN-RTSRLIGKKMNRSVSLTIY-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47810-1", "uniprot_id": "WEE1_MOUSE", "id": "P47810-1", "name": "Wee1-like protein kinase", "aln": "MSFLS-RQQPPPTRRVGAAYSLRQKLIFSPGSDCEEEEEEEEE-GSGHSTGEDSAFQEPDSPLPSARSPAEAEAERRRRSPGAEPSSPGELEDDLLLQGGGGGAQAAGGGAEGDSWEEEGFGSSSPVKSPSTAYFLSSPFSPVRCGGPGDASPQGCGAPRAMDDPCSPQPDYPSTPPHK-TFRKLRLFDTPHTPKSLLSKARVID---------SGSVKLRGSSLFMDTEKSGKREFDTR---QTPQVNINPFTPDPVLLHSSGRCRG-RKRAYF------------NDSS-EDMEASDYEFEDETR-PAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPN----AVSEEGDEDDWIS----------NKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYSHLPKADIFALALTVVCAAGAEPLPRNGEQWHEIRQGRLPRIPQVLSQEVTELLRVMIHPDPERRPSAMELVKHSVLLSA-SRKSAEQLRIELNAEKFKNSLLQKELKKAQMAAKVAAEERALFTDRMATRSTTQSN-RTSRLIGKKMNRSVSLTIY-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30291-1", "uniprot_id": "WEE1_HUMAN", "id": "P30291-1", "name": "Wee1-like protein kinase", "aln": "MSFLS-RQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRR-SPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHK-TFRKLRLFDTPHTPKSLLSKARGID---------SSSVKLRGSSLFMDTEKSGKREFDVR---QTPQVNINPFTPDSLLLHSSGQCRR-RKRTYW------------NDSCGEDMEASDYELEDETR-PAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPN----AASEEGDEDDWAS----------NKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSA-SRKSAEQLRIELNAEKFKNSLLQKELKKAQMA-KAAAEERALFTDRMATRSTTQSN-RTSRLIGKKMNRSVSLTIY-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYE1-1", "uniprot_id": "Q1LYE1_DANRE", "id": "Q1LYE1-1", "name": "Wee1-like protein kinase", "aln": "MSFGAGRHGKSPNLKP-----VRQKLQFST-SDGEEDSIEDAN----NSTGAESGFTELDSPVPLRRS-----LEKRPEDLGN--SSP-----------------LSRNRDDDESWDEEGFGSPSRVKP---AFYMKSSPSPRKSPPAYDSSPERSYIHDDMEGSSSPIPDCPDTPPHK-TFRKLRLFDTPHTPKSLLSRARTMG---------STS---RRVALFTNVDSTSKACLDGKRN-QTPRVNINPFTPDSILVQSSTLQRNNRKRSHW------------NDSCGEDMDASDAEIEDELIPPSKRITMMENNMMSRYASEFHELEKIGSGQFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYYSAWAEDDHMLIQNEYCNGGTLSDVIAENNRRMHFLSELELKDLLLQVSRGLKYIHSTALVHMDIKPSNIFISRKPAAS----VEEFE-DEEDGPT----------TNVVYKIGDLGHVTTVTNPQVEEGDSRFLANEVLQEDYSNLKKADIFALALTVVSASGAEPLPTNGDKWHKIRQGILPHIPQVLSQEFLSLLKLMIHPDPTRRPSTSELVRHPVLLTA-SRMSADQLRVELNAEKFKNALLQKELKKAQMA-KAAAEERVLTTDRVLTRSTIQSSSRASRLIGKKMNRSVSLTIY-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LIS8-1", "uniprot_id": "A0ABK0LIS8_RAT", "id": "A0ABK0LIS8-1", "name": "Wee1-like protein kinase", "aln": "MVLYCLLKNAEPLIKIYS---VSHSETFSPACTEMADAETDQE----LNKKLNFSFCEEDTENEGQMT---------AQDIGR---------------------AQSQKPRRDQSEELEGPVSSPRD------ELYTSLNRDKQSPGP------------ALRTSVSDFSTCPDTPVLN-SKSKLPVPTNFSTPKNLLGQPEISS---------LEKLYVRSSKHLRLTPTSLMDEKTSL-----SLVNINPFTPETYRKLFLQSKGKRKTRDYL------------EETG-------EGESK-AMWLPAKRSVLQETNMASRYEKEFFEVEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSN-DLDLHEVYAHAVLGHHPHVVRYYSSWVEDNHVVIQNEYCNGGSLQAAISENADSDNHFQEPKLKDILLQISLGLKYIHNSGMVHLDIKPSNIFICHKIQSDCPVGPEETESEADWFLN----------ANVMYKIGDLGHATSISKPKVEEGDTRFLANEILQENYQHLPKADIFALGLTIAMAAGAEPLPINGDKWHHIRKGNFPEISQELSDDFYGLLKNMIHPVPEERPSAATLARSRILWPF-LEK-TEELQKQLNLEKSKTATLKRELKKAQHIHTPQRDVHH---CYQQTYKSSRST--RHLLVGGRRKEPPSFTCGAASV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66JT0-1", "uniprot_id": "WEE2_MOUSE", "id": "Q66JT0-1", "name": "Wee1-like protein kinase 2", "aln": "----------------------------------MADTETDQG----LNKKLSFSFCEEDTESEGQMT---------AQDIGG---------------------AQSQKPGREESEELEGPVPPTRD------ELHTSLSRDKESPGP------------DLWKSVSGPPKCPETPVLH-SKSKLPVPTNFSTPKNSLGQPEISL---------LEKLSSRSSRHMRLTPASLMDEKTSL-----SLVNINPFTPETYRKLLLQSKGKRKTRDYL------------EETG-------EEESKSVQWLPAKRSILQETNMASRYEKEFFEIEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSN-ELDLHEVYAHAVLGHHPHVVRYYSSWIEDDHVVIQNEYCNGGSLQAAISENTASNNHFQEPKLKDILLQISLGLKYIHNSGMVHLDIKPSNIFICHKMQCDSPVGPEEAESEADWFLN----------ASVMYKIGDLGHATSISKPKVEEGDTRFLANEILQENYQHLPKADIFALGLTIAVAAGAESLPINGDMWHHIRKGNFPEISQELSDDFYGLLKNMIHPAPKERPSAAALARSRILWPF-LEK-TDELQKQLNLEKSKTATLKRELKKARHIQTPQREVHH---CYYQICKGSR-----HLLVGGRRKAPSSFTRGTSSV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C1S8-1", "uniprot_id": "WEE2_HUMAN", "id": "P0C1S8-1", "name": "Wee1-like protein kinase 2", "aln": "----------------------------------MDDKDIDKE----LRQKLNFSYCEE-TEIEGQKK---------VEESRE---------------------ASSQTPEKGEVQDSEAKGTPPWTPLSNVHELDTSSEKDKESPDQ------------ILRTPVSHPLKCPETPAQPDSRSKLLPSDSPSTPKTMLSRLVISP---------TGKLPSRGPKHLKLTPAPLKDEMTSL-----ALVNINPFTPESYKKLFLQSGGKRKIRGDL------------EEAG-------PEEGK--GGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAIKRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMIIQNEYCNGGSLQAAISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFICHKMQSESSGVIEEVENEADWFLS----------ANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQEDYRHLPKADIFALGLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMIQPDAEQRPSAAALARNTVLRPS-LGK-TEELQQQLNLEKFKTATLERELREAQQAQSPQGYTHHGDTGVSGTHTGSRS---TKRLVGGKSARSSSFTSGEREPLH-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LX51-1", "uniprot_id": "WEE2_DANRE", "id": "Q1LX51-1", "name": "Wee1-like protein kinase 2", "aln": "----------------------------------MKWSEMASV----NATQQHLNFSSSWEEDS------------------------------------------SDNSFDEWTHKSVPLRSPCRT---------PRIQRHRN-------------------RSITVSPSVPTSPIPYAAWKKLRLCDSPSTPKSLLSKSTMPC---------SSSKTCRSQRFLRLSTAFER----------VPSVNINPFTPDTVRRNSEHYKRKSQRSDDD------------EDYGPRSKEIQNSSEDESFFLPSKRPAVSAR-MLSRYESEFLELACIGVGEFGSVYRCVKRLDGCMYAIKRSRRPIAGSANEQLALKEVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEYCDGGSLHDAITEKREQGEFFSVPELRDLLLQVSMGLKYIHNSGLVHLDIKPSNIFICRRSTLS--AGGEGDSEEEDESHS----------SGVVYKIGDLGHVTSISSPQVEEGDSRFLAYEVLREDYTHLPKADIFALGLTVLLAAGASPLPQNGDDWHRLRQGELPNLPHELPALFKDLLKSLLDPDPTARPSATALCRHDVLCKERAGKLATQLRKELNVEKFRTAMLERELKEARLAATSPQ-------QSCQPGSLPKAK---RKLVGRNVARSVSFGFPGY-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54350-1", "uniprot_id": "WEE1_DROME", "id": "P54350-1", "name": "Wee1-like protein kinase", "aln": "--------------------------------MAFRQSEHEMS----VTSLDSSVELRSRSPSPQVFN------------------------------------PRKLRFADDDFDKDTPEGASPQHPLQQRPKLSSGEEQQLDSKIG----------------KEGGDGDVSMSPPCQ-KVRALRLFSTPATPKTILQKSTTQCSNHLSAAAAAVNASRRSDDLFRLSERPRSLPLHNRKLPTQDTANVNPFTPDSLMAHNKKRCRTQFGRENLNLNVNAMQKYLLSDACDDDVTEEAGDSMREIHQQAPKRLALHDTNISRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSLHARIQD-----HCLGEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKIGDLGHVTSVKEPYVEEGDCRYLPKEILHEDYSNLFKADIFSLGITLFEAAGGGPLPKNGPEWHNLRDGKVPILP-SLSRDFNELIAQMMHPYPDKRPTSQSIFSHPILSAV-DSKSKLQLGLELTVEKRKNEILMNKLREAKKQIKLLEQRVNLLAVTNNPDSLDGQRCLRSFTRRMRTPFSSHGKFDSISDRNKNVITNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . :* * . ***. * : . * : .*:*****:. .: . : : **: ** :: ** *:** *::*::*****:****:* :..: . *.**:******:* :****:*:* **:*::****:*:**:* : : : :*: :*::: **.***. :**:*:**.*** . . : * :*******.* :..* ***** *:*. *:*:*:* :* *****:*.:*: *:*. .** ** **.:*.* .* :. *. . *: ::.* . **:: : :* :* :*. ** :. * .:*::*: . . . . ", "identical_positions": 129, "similar_positions": 113, "identity": "18.3%" }, { "cls_id": "homologset.agr.FB:FBgn0011739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2K4-1", "uniprot_id": "F1M2K4_RAT", "id": "F1M2K4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKRGEKPEGYRQMRPKTFPASNYSGSSRQMLQ--EIRESLRNLSK---------PSDAAKAEHNLNKMSTEDPRQ---VRNPPKFGTHHKALQEIRNSLLPFANETS---SSRIPSEVN-PQMFQDLQAAGFDEDMVIQALQKTNNRSIEAAVEFISKMSYQDPRREQMAAAAARPINATMK---PGNVQHSISR---KQSWKGSKESLVP---QRHGPSLGENVVYRSESPNSQADVGRPLSGSGITAFAQAHP--SNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSTS--KFNFTPGRPGVQNGGGQTDFIMHQNVVPTGAVNRQPPPPYPLTPANGQSPSALQAGGPAAPPSFSN--GNVPPTMMVPNRNSHNMELYNINVP----GLQTTWPQSSSAPVQSSPSSGHEIPTWQPN--IPVRSNSFNNPLG-----------SRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWMPQPVQTVQ------PSPFSEGA-------ASNVPVIPPVAEAPSYQGPPPPYPKHLLHQ----------TPSVPPYES--ASKPCKDDQPSSAKEED-SEK--SLDSVDSGDKEKKQITTSPITVRK--NKKDEERR-ESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTK-ALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQ-SGDHPRQDSMDFSSEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQ-SASYIPKITHPTDTSNFDPVDPDK---LWSDG-NEEENINDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYVSSQGS------EQQSDEDDQHTGSDVNNRDLVYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYR2-1", "uniprot_id": "LATS1_MOUSE", "id": "Q8BYR2-1", "name": "Serine/threonine-protein kinase LATS1", "aln": "MKRGEKPEGYRQMRPKTFPASNYPGSSRQMLQ--EIRESLRNLSK---------PSDASKAEHNLNKMSTEDPRQ---VRNPPKFGTHHKALQEIRNSLLPFANETS---SSRSPSEVN-PQMFQDLQAAGFDEDMVIQALQKTNNRSIEAAVEFISKMSYQDPRREQMSAAAARPINATMK---PGNVQHSINR---KQSWKGSKESLVP---QRHGPSLGENVVYRSESPNSQADVGRPLSGSGIAAFAQAHP--SNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPSSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLTTSPMNPPSQAQRAISSVPVGRQPIIMQSTS--KFNFTPGRPGVQNGGGQSDFIVHQN-VPTGSVTRQPPPPYPLTPANGQSPSALQTGASAAPPSFAN--GNVPQSMMVPNRNSHNMELYNINVP----GLQTAWPQSSSAPAQSSPSGGHEIPTWQPN--IPVRSNSFNNPLG-----------SRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWMPQPVQTVQ------PTPFSEGT-------ASSVPVIPPVAEAPSYQGPPPPYPKHLLHQ----------NPSVPPYES--VSKPCKDEQPSLPKEDD-SEK--SADSGDSGDKEKKQITTSPITVRK--NKKDEERR-ESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTK-ALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQ-SGDHPRQDSMDFSNEWGDPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQ-SASYIPKITHPTDTSNFDPVDPDK---LWSDG-SEEENISDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYIHSQGS------EQQSDEDDQHTSSDGNNRDLVYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95835-1", "uniprot_id": "LATS1_HUMAN", "id": "O95835-1", "name": "Serine/threonine-protein kinase LATS1", "aln": "MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQ--EIRESLRNLSK---------PSDAAKAEHNMSKMSTEDPRQ---VRNPPKFGTHHKALQEIRNSLLPFANETN---SSRSTSEVN-PQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMK---PGNVQQSVNR---KQSWKGSKESLVP---QRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHP--SNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSS--KFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTN--GSIPQSMMVPNRNSHNMELYNISVP----GLQTNWPQSSSAPAQSSPSSGHEIPTWQPN--IPVRSNSFNNPLG-----------NRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQ------PSPFPEGT-------ASNVTVMPPVAEAPNYQGPPPPYPKHLLHQ----------NPSVPPYES--ISKPSKEDQPSLPKEDE-SEK--SYENVDSGDKEKKQITTSPITVRK--NKKDEERR-ESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTK-ALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQ-SGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQ-SASYIPKITHPTDTSNFDPVDPDK---LWSDD-NEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGS------EQQSDEDDQNTGSEIKNRDLVYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7G4-1", "uniprot_id": "A0A8M2B7G4_DANRE", "id": "A0A8M2B7G4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MRRAEKPEGYRQMRPKTFPASNNSGNSQQMLQ--EIRESLRNLSP---------SSNASKPEQSSGKGPPDESRQQG-RSTNPRNSHHHRALQEIRKSLQPFAHDSS---SSGDNSSADSSKHTLQTQEPGFDEELMVN------------------RINFQEAVREQIP--SARPVNTAIKQAGPPQIQQPLLR---RQSWKGSKESLAP---QRHSALINDVLIYRPSSPGPQSDLSRPAT----FPQNLASA--SSGQRVNAPLSRQVRSITPP----------------PSSWDSNPSTKRYSGNLDYLVPRISPVPQGPRGDGY---------INPQSQNQRGLSPVPVGRQPIIMQNSNSNKFNFPPSWP--QNGSMQNEYMGMNS-----GARQPPPPPYSMHQTNRQSPTAQQMQSSALTAPPNG--ASLPQSMLVPNRNSHNLDMYNLGV------IRPPVQQAQTPPGQDTSSS------WTHS--VPGRSNSFTSTPN-----------NRR-QCPNSQLSATTVTTVTQAPILQPVKSMRVQKPELHTAVAPAHPPWLQPPPPTAY------QEPPTP---------------PAPAAEVPSYQGPPPPYPKHLLQQ----------QQPPPGYDSSPALKPCSKEGDAADNEND-TDSTCSSERAEGSEEEKKQITTSPVPVRR--HKRDEERKGESRLPMYSPQAFKFFMEQHVENILKNHQQRMRRKKQLESEMQRVGLSGDAQEQMRMMLSQKESNYIRLKRAKMDKCMFEKIKTLGIGAFGEVCLARKVDTG-ALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFQEDLAQFYIAELICAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQ-SGDHVRQDSMDFSMEWEDSANCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMVVGQPPFLATTPLETQMKVIRWQTSLHIPLQAKLSPEATDLILKLCRGPDDRLGRNGADEIKAQPFFRTIDFSKDLRQQHQAPYIPKITHSTDTSNFDPVDPDK---LWSED-ADG-NHNDTLTRWFKNGKHPEHAFYEFTFRRFFDDNGHPYSCPKPIESE--EEDED------EDYVEEDEPSQRPMEQSRDLVYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K4A8-1", "uniprot_id": "A0A0G2K4A8_RAT", "id": "A0A0G2K4A8-1", "name": "non-specific serine/threonine protein kinase", "aln": "------------MRPKTFPATTYSGNSRQRLQ--EIREGLKQPAKSSTQGLLVGPNSDTSSLDAKVLGNKDASRQQQ-MRATPKFGPYQKALREIRYSLLPFANESG----TSAAAEVN-RQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLDPRNEQIV----RVIKQTSP--GKGLVPTAVTR---RPSFEGTG-EAFPSH-HQLGGANYEG-------PAALEEMPR-QYLDFLFP------------------GASVHG-APAHQHPP------------KGYSTAVDAG-THFP----------------GAHYG---------RAHLLS--EQPGYGVQRSPSFQSKTPPDT---YSSL-AKAQGGPP-ASLTFP---AHAGLYTTSHHKPAAAVPGAHPLHVLGTRGPTFTGDSS------TQAVLAPSRNSLNNDLYELGSP--VPWPAAPLARRDSLQKQSLEAS-RPHVAFR---AGPSRTNSFSSPQP-----------------EPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAP-TAPA-----AAEGLESKE------GSAGPPPLDMDFGGSERRCPPPPYPKHLLLP-------SKSEQYSAGLDRLCTG--VEQSLRGG-TEQDRNDKGHKGAKGDKAGRDKKQIQTSPVPVRK--NSRDEEKR-ESRIKSYSPYAFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCETEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTH-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-KGNHIRQDSMEPGDLWDDVSNCRCGDRLKTLEQRAQKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPTQVKLSAEARDLITKLCCAADCRLGRDGADDLKAHPFFSTIDFSRDIRKQ-PAPYVPTISHPMDTSNFDPVDEES---PWHEASGESAKAWDTLA--SPNSKHPEHAFYEFTFRRFFDDNGYPFRCPKPS----EPAES----------ADPGDAELGGAVEGCQPVYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSJ6-1", "uniprot_id": "LATS2_MOUSE", "id": "Q7TSJ6-1", "name": "Serine/threonine-protein kinase LATS2", "aln": "------------MRPKTFPATTYSGNSRQRLQ--EIREGLKQPSKASTQGLLVGPNSDTS-LDAKVLGSKDASRQQQ-MRATPKFGPYQKALREIRYSLLPFANESG----TSAAAEVN-RQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLDPRNEQIV----RVIKQTSP--GKGLAPTPVTR---RPSFEGTG-EALPSY-HQLGGANYEG-------PAALEEMPR-QYLDFLFPGA----------------GAGTHG-AQAHQHPP------------KGYSTAVEPS-AHFP----------------GTHYG---------RGHLLS--EQPGYGVQRSSSFQNKTPPDA---YSSM-AKAQGGPP-ASLTFP---AHAGLYTASHHKPAATPPGAHPLHVLGTRGPTFTGESS------AQAVLAPSRNSLNADLYELGST--VPWSAAPLARRDSLQKQGLEAS-RPHVAFR---AGPSRTNSFNNPQP-----------------EPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVAAP-TAP------ATESLETKE------GSAGPHPLDVDYGGSERRCPPPPYPKHLLLP-------SKSEQYSVDLDSLCTS--VQQSLRGG-TEQDRSDKSHKGAKGDKAGRDKKQIQTSPVPVRK--NSRDEEKR-ESRIKSYSPYAFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKLDTH-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-KGNHMRQDSMEPGDLWDDVSNCRCGDRLKTLEQRAQKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCCAADCRLGRDGADDLKAHPFFNTIDFSRDIRKQ-PAPYVPTISHPMDTSNFDPVDEES---PWHEASGESAKAWDTLA--SPSSKHPEHAFYEFTFRRFFDDNGYPFRCPKPS----EPAES----------ADPGDADLEGAAEGCQPVYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRM7-1", "uniprot_id": "LATS2_HUMAN", "id": "Q9NRM7-1", "name": "Serine/threonine-protein kinase LATS2", "aln": "------------MRPKTFPATTYSGNSRQRLQ--EIREGLKQPSKSSVQGLPAGPNSDTS-LDAKVLGSKDATRQQQQMRATPKFGPYQKALREIRYSLLPFANESG----TSAAAEVN-RQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLDPRNEQIV----RVIKQTSP--GKGLMPTPVTR---RPSFEGTG-DSFASY-HQLSGTPYEGPSFGADGPTALEEMPR-PYVDYLFP------------------GVGPHGPGHQHQHPP------------KGYGASVEAAGAHFPLQ--------------GAHYG---------RPHLLVPGEPLGYGVQRSPSFQSKTPPETGG-YASLPTKGQGGPPGAGLAFPP--PAAGLYVPHPHHKQAG-PAAHQLHVLGSRSQVFASDSP------PQSLLTPSRNSLNVDLYELGSTSVQQWPAATLARRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFNSHQPRPG---------PPGKAEPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPAAEGLDAKEEHALALGGAGAFPLDVEYGGPDRRCPPPPYPKHLLLR-------SKSEQY--DLDSLCAG--MEQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRK--NSRDEEKR-ESRIKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTH-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-KGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQ-PAPYVPTISHPMDTSNFDPVDEES---PWNDASEGSTKAWDTLT--SPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAES----------SDLESSDLVDQTEGCQPVYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S8I4-1", "uniprot_id": "B0S8I4_DANRE", "id": "B0S8I4-1", "name": "non-specific serine/threonine protein kinase", "aln": "------------MRPKTFPATPYVGNTRQRLQ--DIKEGLKQPAKLVSQALHGGSSRGEGGRGGDSKGKDQAARQQQ-LRPPQKFNNYQSALREIRKSLRPYANDSGPGSSSGHPGEVS-RQMLQDLVNAGCDQEMAVRALKQTGSRNIEAALEYISKMSYLDPHTEQIV----RVIKQTSP--GKSGMPNLMDH---RTAMEGSGDGALPPY-HQMGAPLYEGASYGAEGEMARAYMGGPPVMNYMPPPANPSQGATMGNPMGRPASMGAYSTNMAPQNNTGNPMYTPGPAQQKGYPSGIDQAMMGYSVSGPPMQIQSQPSGGPGAHYDY--------RSHMME---NSSYGVKRSASFQNKMPQLTTENYVNMPSKAAMGQN-AGGYAP------NLYLPPHSHPRQASPTSHQVHMMQRPPGVAPGAMGGEFSDVPQGLLTPSRASLNLDLYEH------HWPGAQGPEGTPPARQ-------PQGPFRGEVRVPSRTNSFNNHQKVTVRQTLPPTASVAGKPESSLGPPNTITAVTSPPIQPPVKSIRVMRPEPKTAVGPCHPGWLSAQ--SPE-----AQDSLGYIP--------DENFTLEPSQ---EHRCPPPPYPKTLLVSGSGPEPASLEPVAMSGLQDVSATGRTIQSSSVGKQEESIFKDKVKMGKGEKAVKDKKQIQTSPVPVRK--NARDEEKR-ESRIKSYSPFAFKFYMEQHVENVMKTYQQKLNRRMQLEQEMSKAGLSEAEQEQMRKMLYQKESNYNRLRRAKMDKSMFVKIKTLGIGAFGEVCLTRKVDTG-ALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVRLYYSFQDRDNLYFVMDYIPGGDMMSLLIRMGVFPEVLARFYVAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ-KGNHIRQDSMEPSDFWDDVSNCRCGDRLMTLEQRATRQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLQVPPQVKLSPEAVDIIGQLCCSAEERLGGNGAGEIKAHPFFSEVDFSSNLRTQ-PAPYRPKIAHPMDTSNFDPVEEEGGPGAWSDS-GDSTRTWDTLC--SPHGKHPEHAFYEFTFRRFFDDNGCPFRYPKPLEATQSLSSSDGAGSLKPELEEEEAHEEEEQGEGCEPVYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA38-1", "uniprot_id": "WARTS_DROME", "id": "Q9VA38-1", "name": "Serine/threonine-protein kinase Warts", "aln": "---MHPAGEKRGGRPNDKYTAEALESIKQDLTRFEVQNNHRNNQN-------YTPLRYTATNGRNDALTPDYHHAKQPMEPPPSASPAPDVVIPPPPAIVGQPGAGS---ISVSGVGVGVVGVANGRVPKMMTALMPNKLIRKPSIERDTASSHYLRCSPALDSGAGSSRSDSPHSHHTHQP--SSRTVGNPGGNGGFSPSPSGFSEVAPPAPPPRNPTACSAATPPPPVPPTSQAYVKRRSPALNNRPPAIAPPTQRGNSPVITQNGLKNPQQQLTQQLKS-----------LNLYPGGGSGAVVEPPPPYLIQG------GAGGAAPPPP-----PPSYTASMQSRQSPTQSQQSDYRKSPSSGIYSATSAGSPSPITVSLPPAPLAKPQPRVYQARSQQPIIMQSVKSTQVQKPVLQTAVAPQSPSSASASNSPVHVLAAPPSYPQKSAAVVQQQQQAAAAAHQQQHQHQQSKPPTPTTPPLVGLNSKPNCLEPPSYAKSMQAKAATVVQ-------QQQQQQQQQQQVQQQQVQQQQQQQQQQLQALRVLQAQAQRERDQRERDQRERERDQQK-----LANGNPGRQ-------MLPPPPYQSNNNNNSEIKPPSCNNNNIQIS----------NSNLATTPPIPPAKYNNNSSNTGANSSGGSNGS-TGTTASSSTSCKKIKHASPIPERKKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEP---WEEYSEN--GPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKS-VDEVKSHDFFKGIDFA-DMRKQ-KAPYIPEIKHPTDTSNFDPVDPEK---LRSND--STMSSGDDVD----QNDRTFHGFFEFTFRRFFDDK-----------------------------------QPPDMTDDQAPVYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :: . :* * ::::. :: . : : . .: :: . . : .. : . :. . : : . : .* . : . : . : . :. . . . : . *. . . : : . . * ::*: . . ::::** :.: : . . **. : : .. . . . . . ** :**:. *: ..**.: * *: *** ****:****:**::*.::*: *: ***.** :.** * :** :* ****** **:******.** *:*.:*:****** *. *:** *** ***** *** *******************:***:*******:*.************:*****:: :* * **:**:**: *::******************** *******************:***** .*.* *****: * : :. * : **:* ::*** ***************** *.*******:*******:**:******** :* *** ***.*:.:*::* *..** ** *:* :** ..: *** . ..::*:: ** :**: ::* * *.* * * *. ********: : : * : ..:. *.*:**********: .. ***", "identical_positions": 303, "similar_positions": 180, "identity": "24.75%" }, { "cls_id": "homologset.agr.FB:FBgn0011740", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWG1-1", "uniprot_id": "A0A0G2JWG1_RAT", "id": "A0A0G2JWG1-1", "name": "Alpha-mannosidase", "aln": "-MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARH-QNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTAN-AEGPPALLPYHTANGSWAVLPEPRPSFFSVSPEDCQFALGGRGQKPELQMLTVSEDLPFDNVEGGVWRQGFDISYSPNDWDAED-LQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALVDQLIEGHQWLERNLGATPRSGWAVDPFGHSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVADRAALLLDQYRKKSRLFRSSVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPEFHVQAQFGTLSEYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLETHLRGAEVLYSLALAHARRSGLTGQYPLSDYAVLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIINAAHYLVLGDKETYSFDPRAPFLQMDDSRVSHDALPE---RTVIRLDS-SPRFVVVFNPLEQERLSVVSLLVNSPRVRVLSEEGQPLSVQISVQWSSAT---------NMVPDVYQVSVPVRLPALGLG--VLQLQPDLDGPYTLQSSVHVYLNGVKLSVSRQTTFPLRVVDSGTSDFAISN-RYMQVWFSGLTGLLKSVRRVDEEQEQQVDMKLFVYGTRTSKDKSGAYLFLPDNEAKPYVPKKPPVLRVTEGPFFSEVAAYYEHFHQVIRLYNLPGVEGLSLDVSFQVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQVQPRKYLKKLPLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILDRRLMQDDNRGLGQGLKDNKITCNHFRLLLERRTLMSPEPGFFSKLAAMFRGLIFSSNTIRNSKVQQERSTSYPSLLSHMTSMYLNTPPLVLPVAKREST--SPTLHSFHPLASPLPCDFHLLNLRMLP-AED-TLPAADAALILHRKGFDCGLEAKNLGFNCTTSQGKLALGSLFHGLDVLFLQPTSLTLLYPLASPSNSTDISLEPMEISTFRLRLG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRK9-1", "uniprot_id": "MA2A2_MOUSE", "id": "Q8BRK9-1", "name": "Alpha-mannosidase 2x", "aln": "-MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARH-QNGGNFPRSQISVLQNRIEQLEQLLEENHDIISRIKDSVLELTAN-AEGPPALLPYHTANGSWAVLPEPRPSFFSVSPQDCQFALGGRGQKPELQMLTVSEDLPFDNVEGGVWRQGFDISYSPNDWDTED-LQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALVDQLIEGHQWLERNLGATPRSGWAVDPFGHSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQMWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVADRAALLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPEFHVQAQFGTLSEYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEILYSLALAHARRSGLAGQYPLSDFALLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIINAAHYLVLGDQETYSFDPGTPFLQMDDSRVSHDALPE---RTVIRLDS-SPRFVVVFNPLEQERLSVVSLLVNSPRVRVLSEEGQPLSVQISVHWSSAT---------DMVPDVYQVSVPVRLPGLGLG--VLQLQPDLDGPYTLQSSVRVYLNGVKLSVSRQSAFPVRVVDSGASDFAISN-RYMQVWFSGLTGLLKSIRRVDEEQEQQMELEFLVYGTRTSKDKSGAYLFLPDSEAKPYVPKKPPVLRVTEGPFFSEVAVYYEHFHQVIRLYNLPGVEGLSLDMSFQVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQIQPRQYLKKLPLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILDRRLMQDDNRGLGQGLKDNKITCNRFRLLLERRTTMSP-----------------------EVHQEQERSTSYPSLLSHLTSMYLSTPPLVLPVAKRQGT--SPALRSFHPLASPLPCDFHLLNLRMLP-AED-TLPATDSALILHRKGFDCGLEAKNLGFNCTTSQGKLALGSLFHGLDVTFLQPTSLTLLYPLASPSNSTDISLEPMEISTFRLRLG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49641-3", "uniprot_id": "MA2A2_HUMAN", "id": "P49641-3", "name": "Alpha-mannosidase 2x", "aln": "-MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRH-QNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTAN-AEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAED-LQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPE---RTVIQLDS-SPRFVVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSAT---------EAVPDVYQVSVPVRLPALGLG--VLQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSN-RYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSE--------------------------VQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLP--GPGLRSFHPLASSLPCDFHLLNLRTLQ-AEEDTLPSAETALILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPMEIATFRLRLG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWC8-1", "uniprot_id": "A0A8M3AWC8_DANRE", "id": "A0A8M3AWC8-1", "name": "Alpha-mannosidase", "aln": "-MKLKKQVTVCGGAIFCVAVFSLYLMLDRVQHDPARR-QNGGNFPRSQISVLQNRIEQLEQLLEENHQIISHIKDSVLELTDTGAISPSGHLPFRSANGSWVLPFDGRPTFLSVKPLDCQFALGRRSQ-TDLQMLDVYSLLNFDNVDGGVWKQGFEITYEPNEWDDEP-LQVFVVPHSHNDPGWIKTFDKYYNDQTQHILNNMVTKMAEDPRRKFIWSEISYFAKWWESADVHKQEVMRKLILSGQLEMVTGGWVMTDEANAHYFAMIDQLIEGHQWLERNLGVTPRSGWAVDPFGHSATMPYLLKRANISSMLIQRVHYSIKKHFAATRSLEFMWRQAWDIESSTDMFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGSRVNCPWKVPPRAINDANVAERAGVLLDQYRKKSKLFRSKVLLVPLGDDFRYDKALEWDQQYLNYQKLFDYMNSHPEMHVKAQFATLSDYFDAVYKANGVTSGARPPDYPVLSGDFFAYADREDHYWSGYYTSRPFYKNLDRILESHLRGAEILYSLAVAHARHAGVEGRYPVSDYSLLTDARRNIGLFQHHDAITGTAKEAVVIDYGNRLLRSLVGLKRVIINAAHFLIIKNKDIYRFYQTEPFLETDDRRATQDSLPQ---RTLIELES-SPRYLVLFNPVEQERLCLVTVLVNSARVRVLTEDGQTLPVQLSAQWMSAT---------EMSGEVYQASFMARLPALGLA--VFHLYDSADSPMTLRSETLLRVPGRGQSIRGLDPLPVRSQTVDGQPFYIQT-QSLTLGFSGATGLLESIRRKDDPQEVRVQIQFLTYGTRPSKDKSGAYLFLPDGNAKPYSQRETPIVRVVEGPLFAEVVAHYQHFQQTVRIHNVPGVDGLSLDITTMVDIRDQNNKELAMRFVTDIQSGDTFYTDLNGFQIQPRRYFQKLPLQANFYPMPSTAYIQDSQYRLTLHTAQALGVTSLASGQLEVILDRRLMQDDNRGLGQGLKDNKRTANRFRLLLERRSNSAKPAGSYAKVTNMLNKIIAGILGDGQEEPVDSRPVSFPSLLSHMTSTILNHEVLALPVLPRKHG--VPPMRTFAPLAGTLPCDFHLLNLRSIQSPQDAHSPSPYMALLLHRLGLDCGLEPQNPGFNCTTTQGQLSVSGLFRGLDLQLLQPMSLSLMHSQPPLSNDSSVSLDPMEISAYKLKLC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28494-1", "uniprot_id": "MA2A1_RAT", "id": "P28494-1", "name": "Alpha-mannosidase 2", "aln": "-MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRGPRQEGSFPQGQLSILQEKIDHLERLLAENNEIISNIRDSVINLSESVEDGPRGPAGNASQGS-AHLHSAQLA--LQADPKDCLFASQSGNQHRDVQMLDVYDLIPFDNPDGGVWKQGFDIKYEADEWDREP-LQVFVVPHSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSSRKFIWSEISYLAKWWDIIDNPKKEAVKSLLQNGQLEIVTGGWVMADEATTHYFALIDQLIEGHQWLEKNLGVKPRSGWAIDPFGHSPTMTYLLKRAGFSHMLIQRVHYSVKKHFSLQKTLEFFWRQNWDLGSTTDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRYGCPWGVPPEAISPGNVQSRAQMLLDQYRKKSKLFRTKVLLAPLGDDFRFSEYTEWDLQYRNYEQLFSYMNSQPHLKVKIQFGTLSDYFDALEKSVAAEKKGGQSVFPALSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESRLRTAEILYHLALKQAQKYKINKFLSSPHYTTLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFQSLNSLEKIIGDSAFLLILKDKKLYQSDPSKAFLEMDTKQSSQDSLPK---KNIIQLSAQEPRYLVVYNPFEQERHSVVSVRVNSATVKVLSDLGKAVEVQVSAVWKDMR---------TTSQAAYEVAFLAHLPPLGLK--VYKILESQSSSSHLADYFLYNNDGQAESG----IFHMKNMVDSGDAITIEN-SFLTLGFD-RSGLMEKVRRKEDNKQQELKVQFLWYGTTNKRDKSGAYLFLPDGQGQPYVSLRTPFVRVTRGRIYSDVTCFLEHVTHKVRLYHIQGIEGQSMEVSNIVDIRSVHNREIVMRISSKINNQNRYYTDLNGYQIQPRRTMAKLPLQANVYPMSTMAYIQDAAHRLTLLSAQSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHDNKITANLFRILLEKRNGMNME-------------------------EDKKSPVSYPSLLSHMTSAFLNHPFLPMVLSGQLPSPAIELLSEFRLLQSSLPCDIHLVNLRTIQ-SKVGKGYSDEAALILHRKVFDCQLSSRAMGLPCSTTQGKMSIPKLFNNFAVESFIPSSLSLMHSPPDAQNTSEVSLSPMEISTSRIRLR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27046-1", "uniprot_id": "MA2A1_MOUSE", "id": "P27046-1", "name": "Alpha-mannosidase 2", "aln": "-MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRGPRQEGSFPQGQLSILQEKIDHLERLLAENNEIISNIRDSVINLSESVEDGPRGSPGNASQGS-IHLHSPQLA--LQADPRDCLFASQSGSQPRDVQMLDVYDLIPFDNPDGGVWKQGFDIKYEADEWDHEP-LQVFVVPHSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSSRKFMWSEISYLAKWWDIIDIPKKEAVKSLLQNGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLEKNLGVKPRSGWAIDPFGHSPTMAYLLKRAGFSHMLIQRVHYAIKKHFSLHKTLEFFWRQNWDLGSATDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRYGCPWGVPPEAISPGNVQSRAQMLLDQYRKKSKLFRTKVLLAPLGDDFRFSEYTEWDLQCRNYEQLFSYMNSQPHLKVKIQFGTLSDYFDALEKAVAAEKKSSQSVFPALSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESRIRAAEILYQLALKQAQKYKINKFLSSPHYTTLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFQSLNSLEKIIGDSAFLLILKDKKLYQSDPSKAFLEMDTKQSSQDSLPQ---KIIIQLSAQEPRYLVVYNPFEQERHSVVSIRVNSATVKVLSDSGKPVEVQVSAVWNDMR---------TISQAAYEVSFLAHIPPLGLK--VFKILESQSSSSHLADYVLYNNDGLAENG----IFHVKNMVDAGDAITIEN-PFLAIWFD-RSGLMEKVRRKEDSRQHELKVQFLWYGTTNKRDKSGAYLFLPDGQGQPYVSLRPPFVRVTRGRIYSDVTCFLEHVTHKVRLYNIQGIEGQSMEVSNIVNIRNVHNREIVMRISSKINNQNRYYTDLNGYQIQPRRTMSKLPLQANVYPMCTMAYIQDAEHRLTLLSAQSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHDNKITANLFRILLEKRSAVNME-------------------------EEKKSPVSYPSLLSHMTSSFLNHPFLPMVLSGQLPSPAFELLSEFPLLQSSLPCDIHLVNLRTIQ-SKMGKGYSDEAALILHRKGFDCQFSSRGIGLPCSTTQGKMSVLKLFNKFAVESLVPSSLSLMHSPPDAQNMSEVSLSPMEISTFRIRLRWT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16706-1", "uniprot_id": "MA2A1_HUMAN", "id": "Q16706-1", "name": "Alpha-mannosidase 2", "aln": "-MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLERLLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLS--LSVDTADCLFASQSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEP-LQVFVVPHSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLLAPLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADETQRDKGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIGNSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQ---KNIIRLSA-EPRYLVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTAN---------TISETAYEISFRAHIPPLGLK--VYKILESASSNSHLADYVLYKN-KVEDSG----IFTIKNMINTEEGITLEN-SFVLLRFD-QTGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTCFFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQIQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRILLEKRSAVNTE-------------------------EEKKS-VSYPSLLSHITSSLMNHPVIPMAN--KFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQ-SKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24451-1", "uniprot_id": "MAN2_DROME", "id": "Q24451-1", "name": "Alpha-mannosidase 2", "aln": "MLRIRRRFALVICSGCLLVFLSLYIILN---FAAPAATQIKPNYEN-----IENKLHELENGLQEHGEEMRNLRARLAETSNR--DDP---------------IRPPLKVARSPRPGQCQDVVQDVPN-VDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAG----QAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDG-MARIEER--------LEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQEALKACQMVMQQSVYRLLTKPS-IYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLLRKNPTSLPLG---QYPEDVKFGDPREISLRVGNGPTLAFS-EQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPNGPASP-VELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR------GGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIYRLVLEKVNNCVRP--------------------------SELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIG---AQGQFGGDHPSAREDLDVSVMRRLT---KSSAKTQRVGYVLHRT------NLMQCGTPEEHTQ-KLDVCHLLP--NVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: ::.:: : :..:***::*: . : .: . :::::..**. * *: : : .:: : : : .* . . :* . : ::*** : . : *.: :****:**::*.*.. .:: . *:*************::**:.*: ..*::*:.. : :: ::. :*:*:*:*::::::. . *: :: :: .****:.******.***..*: :: ** **: **:. :...* :.**:****:*.**.*:*.::.:. *****.**::**.:: : ***:*** ** . * :: *********:*********:********: . .*** ***.:* ** *: :*:**::**:.*:*:.*** *******: : *** * **::**..:**:..::*: **.**.::***: : . . :*.******:****.*:**:**:****::* :**:: :* **:* .. : * :*** :.******.****** **:** *: .:* : :: .:.. *: . * .:: * : . ..: . :: . .:.:*:.*.. : * :* . *.*. * * .:.: .*:* * *. . .::* :** * : . . : : : *. **::.: :: . :..:. **. *:********:. ..* *.: *..* : :.* . : : * : :: *:* . * *:.::: :.*.. . ::***** *. * : ******* **: :*:*: **** :.*.** :*: .*::*:: **** .**:*** **: *** . : :*::**: . . ..: : :* :* : : * . *:.: :* : : . :*** . * :* :: : *: : :*::: .. : *** :: ", "identical_positions": 320, "similar_positions": 359, "identity": "26.64%" }, { "cls_id": "homologset.agr.FB:FBgn0011741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L1W3-1", "uniprot_id": "A0ABK0L1W3_RAT", "id": "A0ABK0L1W3-1", "name": "Actin-related protein 6", "aln": "MECHCHRKTMRLKIWIQGLEKRLRCLTSGVLRCQGNRKLSVGHAPINHRVPEEACAEEIQTVEKRPRCGVVGPEMTTLVLDNGAYNAKIGYS-HDSVSVIPNCQFRSKTARLKTFTANQIDEIKDPSGLFYILPFQKGYLVNWDVQRQVWDYLFGK--EMYQVDFLD---TNIIITEPYFNFTSIQESMNEILFEEYQFQAVLRVNALADLELTEIHLSVLLSTGIKAGALSAHRYFRDNPS----------------ELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEDNTVMIDYVLPDFSTIKKGFCKPREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLPEEMQPHFFKNIVLTGGNSLFPGFRERVYSEVRCLTPTDYDVSVVLPE-NPITYSWEGGKLISENDDFEDMVVTREDYEENGHSVCEEKFDI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D864-1", "uniprot_id": "ARP6_MOUSE", "id": "Q9D864-1", "name": "Actin-related protein 6", "aln": "--------------------------------------------------------------------------MTTLVLDNGAYNAKIGYS-HDSVSVIPNCQFRSKTARLKTFTANQIDEIKDPSGLFYILPFQKGYLVNWDVQRQVWDYLFGK--EMYQVDFLD---TNIIITEPYFNFTSIQESMNEILFEEYQFQAVLRVN---------------------AGALSAHRYFRDNPS----------------ELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEDNTVMIDYVLPDFSTIKKGFCKPREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLPEEMQPHFFKNIVLTGGNSLFPGFRERVYSEVRCLTPTDYDVSVVLPE-NPITYSWEGGKLISENDDFEDMVVTREDYEENGHSVCEEKFDI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZN1-1", "uniprot_id": "ARP6_HUMAN", "id": "Q9GZN1-1", "name": "Actin-related protein 6", "aln": "--------------------------------------------------------------------------MTTLVLDNGAYNAKIGYS-HENVSVIPNCQFRSKTARLKTFTANQIDEIKDPSGLFYILPFQKGYLVNWDVQRQVWDYLFGK--EMYQVDFLD---TNIIITEPYFNFTSIQESMNEILFEEYQFQAVLRVN---------------------AGALSAHRYFRDNPS----------------ELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEENTVMIDYVLPDFSTIKKGFCKPREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLPEEMQPHFFKNIVLTGGNSLFPGFRDRVYSEVRCLTPTDYDVSVVLPE-NPITYAWEGGKLISENDDFEDMVVTREDYEENGHSVCEEKFDI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P45890-1", "uniprot_id": "ARP6_DROME", "id": "P45890-1", "name": "Actin-related protein 6", "aln": "------------------------------------------------------------------------MANAVVVLDNGAHTAKVGLANQDEPHVVPNCIMKAKSERRRAFVGNQIDECRDTSALYYILAFQRGYLLNWHTQKTVWDYIFSK--DGIGCSLEN---RNIVITEPQMNFQSIQEATLEILFEEYKVDGVYKTT---------------------AADLAAFNYVADSEERTTME-----------SLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKALTNQLKELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFTTVKRGYVRVPG---KPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPE-DPVRYAWYGGKEVATSPNFEEFVYTQDDYEEYGFQGINQR--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12509-1", "uniprot_id": "ARP6_YEAST", "id": "Q12509-1", "name": "Actin-like protein ARP6", "aln": "------------------------------------------------------------------------METPPIVIDNGSYEIKFGPSTNKKPFRALNALAKDKFG--TSYLSNHIKNIKDISSITFRRPHELGQLTLWELESCIWDYCLFNPSEFDGFDLKEGKGHHLVASESCMTLPELSKHADQVIFEEYEFDSLFKSPVAVFVPFTKSYKGEMRTISGKDEDIDIVRGNSDSTNSTSSESKNAQDSGSDYHDFQLVIDSGFNCTWIIPVLKGIPYYKAVKKLDIGGRFLTGLLKETLSFRHYNMMDETILVNNIKEQCLFVSP-----VSYFDSFKTKDKHALEYVLPDFQTSFLGYVRNPRKENVPLP--EDAQIITLTDELFTIPETFFHPEISQITKPGIVEAILESLSMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLPTDWTCHVSVPEGDCALFGWEVMSQFAKTDSYRKARVTREEYYEHGPDWCTKHRFGYQNWI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*:***:: *.* : :.. *. : * :: .*:*.: :* *.: : ..: * * *. : :*** : : : .: : ::: :*. :.: .:.: :::****:.:.: : : . *. . :::* *:. * ::* . :.: ::::**: **. *** :*:*: ::***: ::*::**: :*: :. ::****** * *: : . . *:: * :* *::** :*:*. : : ** **: .:. * : :. **: .**. :*.* *: ::: * * : ** : :.* . .: . .:.. *:::* * * . :: ", "identical_positions": 81, "similar_positions": 141, "identity": "15.61%" }, { "cls_id": "homologset.agr.FB:FBgn0011742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61161-1", "uniprot_id": "ARP2_MOUSE", "id": "P61161-1", "name": "Actin-related protein 2", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61160-1", "uniprot_id": "ARP2_HUMAN", "id": "P61160-1", "name": "Actin-related protein 2", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M7U6-1", "uniprot_id": "ARP2_RAT", "id": "Q5M7U6-1", "name": "Actin-related protein 2", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRSCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7SXW6-1", "uniprot_id": "ARP2A_DANRE", "id": "Q7SXW6-1", "name": "Actin-related protein 2-A", "aln": "MDSQGKKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDSRNCKILLTEPPMNPTKNREKIIEVMFETYQFSGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRVIKVGGERFGAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTREEYQEKGTRVLEKLGVTVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q56A35-1", "uniprot_id": "ARP2B_DANRE", "id": "Q56A35-1", "name": "Actin-related protein 2-B", "aln": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVG-NIEIK-----DLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNINSRDCKILLTEPPMNPTKNREKIIEVMFETYQFTGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKENLCYVGYNIEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWLTREEYQEKGVRVLEKLGVTVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45888-1", "uniprot_id": "ARP2_DROME", "id": "P45888-1", "name": "Actin-related protein 2", "aln": "MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIG-DIEVKDLHVDDLMVGDEASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQKLQKISH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32381-1", "uniprot_id": "ARP2_YEAST", "id": "P32381-1", "name": "Actin-related protein 2", "aln": "MDP--HNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEERASVATPLK-----DIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTSNGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEKLCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPGVGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPSRLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. :: :* *:****** * **.*** : **::****::*: : . :* *:*:*****::** *::.******:::** ** :***:* : .. . *********** *****: *****.* * ..*:******:****** :***:********* **** . *.*******:****:**:**.** ******::******* :**:***:.*::: : :** ***.***** ***** **** *** ***.**** *::** *:.** ***:*:**:* *..:** *******:**********:*:***::.***:.* .:* ***:*********.***:******.: *:* :*::::*:**.* .: *: ", "identical_positions": 237, "similar_positions": 94, "identity": "59.25%" }, { "cls_id": "homologset.agr.FB:FBgn0011743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y615-1", "uniprot_id": "ACL7A_HUMAN", "id": "Q9Y615-1", "name": "Actin-like protein 7A", "aln": "-----MWAPPAAIMGDGPTKKVGNQAPLQTQALQTASLRDGPAKRAVWVRHTSSEPQEPTESKAAKERPKQEVTKAVVVDLGTGYCKCGFAGLPRPTHKISTTVGKP-YMETAKTGDNRKETFVGQELNNTNVHLKLVNPLRHGIIVDWDTVQDIWEYLFRQEMKIAPEEHAVLVSDPPLSPHTNREKYAEMLFEAFNTPAMHIAYQSRLSMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTAYLLGLLNSAGNEFTQD-QMGIVEDIKKKCCFVALDPIEEKKVPLSE-----HTIRYVLPDGKEIQLCQERFLCSEMFFKPS-LIKSMQLGLHTQTVSCLNKCD-IALKRDLMGNILLCGGSTMLSGFPNRLQKELS-SMCP--NDTPQVNVLPERDSAVWTGGSILASLQGFQPLWVHRFEYEEHGPFFLYRRCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QY84-1", "uniprot_id": "ACL7A_MOUSE", "id": "Q9QY84-1", "name": "Actin-like protein 7A", "aln": "MSLDGVWAPQTANIGDGPAKKASDQASMQTQVLQTASLKDGPAKRAVWVRRDNAETEDPVKSTMSKDRPRLEVTKAVVVDLGTGFCKCGFAGLPKPTHKISTTVGKP-YMETAKTGDNRKETFVGHELFNPDIHLKLVNPLRHGIIVDWDTVQDIWEYLFRQEMKIAPEEHAVLVSDPPLSPHTNREKYAEMLFETFNTPAMHIAYQSRLSMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTTYLMNLMNNSGKHFSED-HLGIVEDIKTRCCFVALDPIEEKKIPAPE-----HEIHYTLPDGKEIRLGQERFLCSEMFFKPS-LIKSMQLGLHTQTVSCLNKCD-IALKRDLMGNILLCGGSTMLRGFPNRLQKELS-SMCP--NDTPQVNVLPERDTAVWTGGSILASLQGFQPLWVHRLEYEEHGPFFLYRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QY83-1", "uniprot_id": "ACL7B_MOUSE", "id": "Q9QY83-1", "name": "Actin-like protein 7B", "aln": "----------------MATKNSPSPKPMGTAQGDPGEAGTLPAPEAAGIRDTG-STQLKTKPKKIRK------IKALVIDLGSQYCKCGYAGEPRPTYFISSTVGKRSAEMAADAGDNFKETYVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKIMPEEHAVLVSDPPLSPTSNREKYAELLFETFGIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPSRVDYAGCDLTNYLMQLLNEAGHKFSDD-HLHIIEHIKKKCCYAALLPEEEMSLGLDE-----LHVDYELPDGKIITIGQERFRCSEMLFKPS-LVGCTQPGLPELTATCLARCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELS-LLCP--GDSPTVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y614-1", "uniprot_id": "ACL7B_HUMAN", "id": "Q9Y614-1", "name": "Actin-like protein 7B", "aln": "----------------MATRNSP--MPLGTAQGDPGEAGTRPGPDAS-LRDTGAATQLKMKPRKVHK------IKAVIIDLGSQYCKCGYAGEPRPTYFISSTVGKR-CPEAADAGDTRKWTLVGHELLNTEAPLKLVNPLKHGIVVDWDCVQDIWEYIFRTAMKILPEEHAVLVSDPPLSPSSNREKYAELMFETFGIPAMHVTSQSLLSIYSYGKTSGLVVESGHGVSHVVPISEGDVLPGLTSRADYAGGDLTNYLMQLLNEAGHAFTDD-HLHIIEHIKKKCCYAAFLPEEELGLVPEE-----LRVDYELPDGKLITIGQERFRCSEMLFQPS-LAGSTQPGLPELTAACLGRCQDTGFKEEMAANVLLCGGCTMLDGFPERFQRELS-LLCP--GDSPAVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGSVAIYSKC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CG27-1", "uniprot_id": "ACTL9_MOUSE", "id": "Q8CG27-1", "name": "Actin-like protein 9", "aln": "---------------MDVNGHPKFQPSPETDGPLP-LTSSTLMVSKSLQQDSLSMVGDRLPPK----------TGAVVIDMGTGTCKVGFAGQSQPTYTVATILGCQ-PKKQATKDQSELETFIG-EAARSRPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSGFSLQQE-DLDLVENIKHHYCYLAPDFQKEQARPDEE-----CKQSLKLPDGRTVTLGKELFQCPELLFHPPEIPGLSPIGLPAMAEQSLLKVP-QELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSP--EDHVVVMAHPNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TC94-1", "uniprot_id": "ACTL9_HUMAN", "id": "Q8TC94-1", "name": "Actin-like protein 9", "aln": "---------------MDASRPKSSESQSSLEAPRPGPNPSPNVVNKPLQRDSPGMVADRLPPK----------TGAVVIDMGTGTCKVGFAGQASPTYTVATILGCQ-PKKPATSGQSGLQTFIG-EAARVLPELTLVQPLRSGIVVDWDAAELIWRHLLEHDLRVATHDHPLLFSDPPFSPATNREKLVEVAFESLRSPAMYVASQSVLSVYAHGRVSGLVVDTGHGVTYTVPVFQGYNLLHATERLDLAGNNLTAFLAEMLLQAGLPLGQQ-DLDLVENIKHHYCYVASDFQKEQARPEQE-----YKRTLKLPDGRTVTLGKELFQCPELLFNPPEVPGLSPVGLSTMAKQSLRKLS-LEMRADLAQNVLLCGGSSLFTGFEGRFRAELLRALPA--ETHVVVAAQPTRNFSVWIGGSILASLRAFQSCWVLREQYEEQGPYIVYRKCY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68134-1", "uniprot_id": "ACTS_MOUSE", "id": "P68134-1", "name": "Actin, alpha skeletal muscle", "aln": "----------------------------------------------------MCDEDE---------------TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSS---SLEKSYELPDGQVITIGNERFRCPETLFQPS-FIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS--TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P68133-1", "uniprot_id": "ACTS_HUMAN", "id": "P68133-1", "name": "Actin, alpha skeletal muscle", "aln": "----------------------------------------------------MCDEDE---------------TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSS---SLEKSYELPDGQVITIGNERFRCPETLFQPS-FIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS--TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P68136-1", "uniprot_id": "ACTS_RAT", "id": "P68136-1", "name": "Actin, alpha skeletal muscle", "aln": "----------------------------------------------------MCDEDE---------------TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRP-RHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSS---SLEKSYELPDGQVITIGNERFRCPETLFQPS-FIGMESAGIHETTYNSIMKCD-IDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPS--TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "------------------------------------------------------MDSE---------------VAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRP-RHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSS---SIEKSYELPDGQVITIGNERFRAPEALFHPS-VLGLESAGIDQTTYNSIMKCD-VDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPS--SMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P45891-1", "uniprot_id": "ACTY_DROME", "id": "P45891-1", "name": "Actin-like protein 53D", "aln": "------------------------------------------------MSSEVDSNSH---------------HAAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRP-RHLNVLLDSVIGDSVIGEAAARKRGILTLKYPIEHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEMDLHG-------KVETYELPDGQKIVLGCERFRCPEALFQPS-LLGQEVMGIHEATHHSITNCD-MDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPP--SIRIKVNASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A2R8RWI7-1", "uniprot_id": "A0A2R8RWI7_DANRE", "id": "A0A2R8RWI7-1", "name": "", "aln": "------------------------------------------------------MTDY---------------KTPIVLDSGSGLMKAGFADQDLPAAVFPTVIGRP-KYEEVMNSCVDRELYVGHDAQHMRGVLTLRYPIRHGVVSNWDEMEMLWTHA-FQLLSAAPEDHPVLLTEAALNPLQNRQRMVELMFEAFSVPLTFVAVQAVLALYASGRTTGVVLDSGDGVSHSVPVFEGYCLPHAVQRLDLAGADVTLQLQKLLLESGVCLRTSAELEIVREMKERCCFVSVDYEAEMKSSE-------SEIQYTLPDGHTVPLASQRFRAPEILFRPE-LIGRDHYGLHESVFRSILQSD-LDLRRSFVGNILLSGGNTLLSGLAERLQLEVRAMVPLDLSACVRVSSPPDRDFSVWSGGAALASLPEQQSAWISAAEYEEFGPQIVFRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9D9L5-1", "uniprot_id": "ACTT2_MOUSE", "id": "Q9D9L5-1", "name": "Actin-related protein T2", "aln": "--------------------------------------------------MFNPLVLD---------------SPSVIFDNGSGLCKAGLSGEIGPRHVTSSVVGYP-KFKAPPTGASQKKYFVGEEALYKQEALSLHYPIDRGLVTSWDDVEKLWRHLFEWELGVKPCERPVLVTEPSLNPRENREKTAEMMFETFEVPAFYLSDQAVLALYSSACVTGLVVDSGDGVTCTVPIYEGYSLPHAVSKLYVAGKDITELLTRLLLASGRAFPCPLEKALADDIKEKLCYVALEPEEELSRRAED-----VLREYKLPDGNVIYIGDQLYQAPEVLFSPD-QLGTHGPGLAQMASNSITKCD-ADIQKTLFGEIVLSGGSTLFQGLDDRLLKELEQLASK--GVPIKITAPPDRWFSTWIGASIVTSLSSFKQMWITAADFKEFGVSVVQRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDY3-1", "uniprot_id": "ACTT2_HUMAN", "id": "Q8TDY3-1", "name": "Actin-related protein T2", "aln": "--------------------------------------------------MFNPHALD---------------SPAVIFDNGSGFCKAGLSGEFGPRHMVSSIVGHL-KFQAPSAEANQKKYFVGEEALYKQEALQLHSPFERGLITGWDDVERLWKHLFEWELGVKPSDQPLLATEPSLNPRENREKMAEVMFENFGVPAFYLSDQAVLALYASACVTGLVVDSGDAVTCTVPIFEGYSLPHAVTKLHVAGRDITELLMQLLLASGHTFPCQLDKGLVDDIKKKLCYVALEPEKELSRRPEE-----VLREYKLPDGNIISLGDPLHQAPEALFVPQ-QLGSQSPGLSNMVSSSITKCD-TDIQKILFGEIVLSGGTTLFHGLDDRLLKELEQLASK--DTPIKITAPPDRWFSTWIGASIVTSLSSFKQMWVTAADFKEFGTSVVQRRCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TDG2-1", "uniprot_id": "ACTT1_HUMAN", "id": "Q8TDG2-1", "name": "Actin-related protein T1", "aln": "--------------------------------------------------MFNPHALD---------------VPAVIFDNGSGLCKAGLSGEIGPRHVISSVLGHC-KFNVPLARLNQK-YFVGQEALYKYEALHLHYPIERGLVTGWDDMEKLWKHLFERELGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFYLSNHAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFASGFNFPCILNKAVVNNIKEKLCYIALEPEKELRKSRGE-----VLGAYRLPDGHVIHFGDELYQVPEVLFAPD-QLGIHSPGLSKMVSSSIMKCD-TDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASK--GTPIKITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D9J3-1", "uniprot_id": "ACTT1_MOUSE", "id": "Q9D9J3-1", "name": "Actin-related protein T1", "aln": "--------------------------------------------------MLDPARLD---------------NPAVIFDNGSGLCKVGISGEIEPRHVINSVVGHP-KFNIPSARSNRKRYFVGEEAQCMYDGLYLHYPIERGLVTRWDDMEKLWKDLFEWELGVKPNEQPVFMTEPSLNPQETREKTTEIMFEKFNVPALYLCNHAVGALCASACITGLVLDSGDGVTCTVPVYEGYSLPHAITKLYVAGRDITEHLTRLLLAKGYTFPCILNKAVVDDIKEKLCTVSLG-YKDTEKNCQQ-----FLRKYTLPDGNTIQMSDHLCQVPEVLFTPD-HLGIHDLGISKMVCNSIMNCD-TDIQENLFAEIVLSGGTTMFPGLQDRLLKELEDLAFE--GTPIKITASSDRCYSAWIGGSVMTSMTTFKQMWVTAEDFKEYGAFVVQRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BXF8-1", "uniprot_id": "ACTT3_MOUSE", "id": "Q8BXF8-1", "name": "Actin-related protein T3", "aln": "------------------------------------------------------MSGY---------------QPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRS-KGHT--ADSRQE-LCVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMMLLKGDGIMLLRTGDRKVVTDIKENACYVAMNYEDEMTKDSN------LEKIYTLPDGKTVKLHKQLFHCPEALFSPY-LVNVDAPGIDKMCFGSIMKCD-TDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPA--NTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYD9-1", "uniprot_id": "ACTT3_HUMAN", "id": "Q9BYD9-1", "name": "Actin-related protein T3", "aln": "------------------------------------------------------MNHC---------------QLPVVIDNGSGMIKAGVAGCREPQFIYPNIIGRA-KGQSRAAQGGLE-LCVGDQAQDWRSSLFISYPVERGLITSWEDMEIMWKHIYDYNLKLKPCDGPVLITEPALNPLANRQQITEMFFEHLGVPAFYMSIQAVLALFAAGFTTGLVLNSGAGVTQSVPIFEGYCLPHGVQQLDLAGLDLTNYLMVLMKNHGIMLLSASDRKIVEDIKESFCYVAMNYEEEMAKKPDC-----LEKVYQLPDGKVIQLHDQLFSCPEALFSPC-HMNLEAPGIDKICFSSIMKCD-TGLRNSFFSNIILAGGSTSFPGLDKRLVKDIAKVAPA--NTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFKEVGPNIVHQRCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KAE0-1", "uniprot_id": "A0A0G2KAE0_RAT", "id": "A0A0G2KAE0-1", "name": "", "aln": "--------------------------------------------------------MD---------------NTPIICDYGSGFSKVGFAGTRVPLAVFPTILGKM-KNATLLERLEEEDWFIGAEVQNNRPKLNIHYPIFRGAITNWDNVQKVWHYSFYHYLRIAPEQHPILVTDPPLTTKEARSKMTQILFETFNFPALYLANQGVLSLYASGRTSGTTIESGDGMTYFVPIANGYPLHLSTTKVDTAGQDLTVYLMKLLSDNGNMLETTADLEHVRDLKEKCCYVALDYDMEMSKTSESS----FLKKFTLPDGKEISLGQETFMCPEVLFNPS-LVGKNYPGIDMQAQQSITSCD-KSHWRNLFGYIILSGGTGTCSGLRFRLQREIAKLVSP--ELSVKVVTSPYAKYGAWVGASILCSLPMFKDMWITNHEYLEIGPSVICRRTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YYH9-1", "uniprot_id": "D3YYH9_MOUSE", "id": "D3YYH9-1", "name": "", "aln": "--------------------------------------------------------ME---------------KTPLVCDYGSGFSKVGFSGTQAPQAVFPTILGKM-KHTNVLEGLGEQDWFIGAETQTNRTELNMYYPISRGAITNWDNVEKIWHYSFYHSLQIAPEQHPILITEAPLTSKEAKSRMTQILFETFNFPALYTANQAVLSLIASGRTSGTAIESGDGMTYFVPVMNGYPLHLSTTKLDIAGQDLTLYLMKLLSDNGNVLETIADLEYIRDLKDKYSYVALDYNMEMSKTSAPS----FQKKFTLPDGKEINLGQEAFMCSEVLFDTS-LLERANPGIHMLTLESIMSCE-KSHQRTLFNYIVLTGGTSACTGLRFRMQKEMAKVVSP--DFCVKVTASPYAKYSAWIGASILSSLPLFKDMWITNHEYLEIGPSVIFRRCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H568-1", "uniprot_id": "ACTL8_HUMAN", "id": "Q9H568-1", "name": "Actin-like protein 8", "aln": "-----------------------------------------------------------------------MAARTVIIDHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENPGPSYARRRVSLGIDICHPD---TFSYPIERGRILNWEGVQYLWSFVLENHRREQ-EVPPVIITETPLREPADRKKMLEILFELLHVPSVLLADQLQMSLYASGLLTGVVVDSGYGLTRVQPFHQGRPLPASGKTLEFAGQDLSAYLLKSLFKEDCDRRCLFQLETVAVTQMNKCYVPQNLGEALDFRERQQSALDESNTYQLPDGSRVELTPMQRVAPEMFFSPQ-VFEQPGPSIPRAIVESVESCE-ISLRPLLVSHVMACGGNTLYPGFTKRLFRELMGDHVS--STKATVWEGSNRNFSVWLGASVVAHLSTYQSEWMSREEYGEHMRM-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: * *: * * : * . :. :* : *. * : * : :* . : ::..: :.: :: ** : * : :: : . * .:: * .:: *. * * ** .:: * : . . : . . **** : : .* :* . .: .: . : ** .: *: :: : . ..* *.: : : : *: :: * ", "identical_positions": 34, "similar_positions": 76, "identity": "7.52%" }, { "cls_id": "homologset.agr.FB:FBgn0011745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5C5-1", "uniprot_id": "ACTY_MOUSE", "id": "Q8R5C5-1", "name": "Beta-centractin", "aln": "---MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRK-EGADFHTSAEFEVVRTIKERACYLSINPQKDE-----ALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AKZ9-1", "uniprot_id": "A0A8I6AKZ9_RAT", "id": "A0A8I6AKZ9-1", "name": "Beta-centractin", "aln": "---MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRK-EGADFHTSAEFEVVRTIKERACYLSINPQKDE-----ALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42025-1", "uniprot_id": "ACTY_HUMAN", "id": "P42025-1", "name": "Beta-centractin", "aln": "---MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRK-EGVDFHTSAEFEVVRTIKERACYLSINPQKDE-----ALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61163-1", "uniprot_id": "ACTZ_HUMAN", "id": "P61163-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P85515-1", "uniprot_id": "ACTZ_RAT", "id": "P85515-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61164-1", "uniprot_id": "ACTZ_MOUSE", "id": "P61164-1", "name": "Alpha-centractin", "aln": "---MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRK-EGYDFHSSSEFEIVKAIKERACYLSINPQKDE-----TLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P45889-1", "uniprot_id": "ACTZ_DROME", "id": "P45889-1", "name": "Actin-related protein 1", "aln": "---MEPYDVVVNQPVVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRR-EGFNFRSTAEFEIVRSIKEKVCYLATNPQKEE-----TVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38696-1", "uniprot_id": "ARP1_YEAST", "id": "P38696-1", "name": "Centractin", "aln": "MDQLSDSYALYNQPVVIDNGSGIIKAGFSGEERPKALEYCLVGNTKYDKVMLEGLQGDTFIGNNAQKLRGLLKLRYPIKHGVVEDWDSMELIWSYVLNEVLQLQNIGEHPLLITEAPMNPLKNREQMAQVLFETFDVSALYVSNPAVLSLYASGRTTGCVVDCGEGYCSTVPIYDGFALPASMMRMDIGGADITEQLQFQLRKSAGVSLFSSSEREIVRTMKEKVCYLAKNIKKEEEKYLQGTQDLISTFKLPDGRCIEVGNDRYRAPEILFSPQIIGLGYDGLSDMCMQSIWKVDLDLRKPLLSSIILSGGTTTLKGFGDRMLWDLEALTKGTSKIKIIAPSERKYTTWIGGSILTGLSTFQRLWTKKSDWLEDSTRVYSNLM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : ***********:*****:*:. ** :*..*: :** .*:** *:* :*:: ****.:***::**:* **:.** **.*: .: :**:*:****:** :***: *:.:** ::..**::* *******:**.** *:*.*:* :****:***:* *:**:**.* *::. *: :*: * .: :::* *:*:::**:.***: * :*:* : : **** :::* *:****:** *:::* :*: :: :* * *:***: * .*:****:* :******:* ::: : **:* **.** *:**:*****:.*.**:::* .* :: *:. : . ", "identical_positions": 164, "similar_positions": 118, "identity": "42.6%" }, { "cls_id": "homologset.agr.FB:FBgn0011747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5N3-1", "uniprot_id": "F1M5N3_RAT", "id": "F1M5N3-1", "name": "", "aln": "-----MMNEDAAQKSDSG-----EKFNGSSQRRKR-------------------------------------PKKCVCSG--LRLSKARTLS--SHNFSAS--KPDFFFSQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYG-ASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG-KNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLG-YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT--EEVTTTTTTITEKHKLNVPETMTEVLDVS------------------DEEGDDTVTGDGGEYLR-----------------------------PEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPSHQVSALAKEAERNSYR-LSWGTENLDNVALSSSPIHSG------------FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLG---------------------------------PVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCEYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGG----DAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQH-HIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRG-LVHQAICNLNITLPIYAKESESDQEQEEEVILQQQHYDETESTETSVL--KSHLVNEVP--------------------------------------------------------------------------------------------------------------------------------------------------VLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELAKAGEEEPGEPFEIVERVKEDLEKVNAILRSGTYMRDEGSVRSSQSER-ELEEEWVIVSDEEIEEAKQHAPVEIAEHPCVEVRVDRETKTK--VEKDSTGLVNYLTDDLNSYTGTHEKKPQTAPEKSGETSQASAIVKSSESNKGKTSPAEEKQSAQKQVKPSLVIKKPVRRKLKEKQKQKEESPQGSEEKTELKKGSSEESVDEDRGLAPEPLPTAKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPVRVKGKEDVPKKTTPRTHPVVSPSSKS------SPSSKMERHSSLTSSAKTERHSPVSPSSKNEKHSPVSPSAKAERHSPVFSG-KPEKHSPGSPSTKNERHSPVSSIKTERHTPVSPSGKTDKRPPVPSSGRTEKHPPVSPGKTEKRSPGAPSIRTPEKQAPGSATGKHEKHLPVSP-GKTEKQP------------------------------PISPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQSQDKSKSRVEKEKGHSVTQ-----RETQRIENQTAKRGQRFQVTGAMESRRFRSTTITVGLRTEDPVRERFERTPVIKTPEAVPPVAAAVAAAAAEESHRGAETLQEKTVDEQEDMDLQISPDRKTSTDFSDVIKQELEDNDKYQQFRLTENTEKAQIHLDQVITSPFNTTFPLDYMKDEFLPALSLQSGALGGSSESLKQEVIAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSKEQIGEAKETIKVETPTDIHSEKELPITNDIADSSEKQGAGVPGDSE----HVLKEVTQVPPKDVCSK-QEDCPGSHSVSLANETCQALTEEGSCRDSQLPLVSSACKTQAVSETQESLATSEVTKAFPPSDATVKTVEGTEPKPQGVIRSPQGLELPLHNRDSEVLSPMADESLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDSSTPKPAVIHECAEEDDSENG--------------EKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYKREPRQDESSSSSDPDADCSAEVDEQKQMGSTEGESDVPVLVTSESRKASSSS-ESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNSSPEEA-QFQPIVPKQYTFKMN-EEVKEDPGNPEEDKDCKSHLAEDSQTHSADGADGSHADLNRETPQLEACDGHGCKAVSPSNSATPVSLGVQSPECHDVDKPLAIDNDSLALQDTHGSDLEEREFDPSRVESTQASLPSE-HSSLSSSSHCAVPEENESAKEISSPSSPVKVEVTVTDPVLESMSEDCPTQEASTTTHTERFAMDGPVSDIAETDENSHPQITSPYENVASSSFFSGEPSNFQTDTCHP-----------------TVVHSPEVYSVIIRSSPEDVIMTSSSSRTDSGEASNCEGHDLDTECEQKSALWPMQSDEPPLSVAPTTPNAPVVTGEQVSKVIITKTDVDADS---------------------------------------------------------------------------WSEIREDDAAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYADES--LHFFQIGQDSNEETISEDLKEGATGAEPPQTETTSESLELSGPKEAMDDEGELVPDDVSEEIEDLPASDADLDSKVVISASTETPTK--------------EAVSTVAEEPATMQWSDS--LSTVKQTSCPTFPEPVG--QLDFSTVTRSVYSDRDDESPDSSPEEQKS-VIEIPTAPMENVPSAEIKPQIPIRTLPTSVSAPPSAEDESAFSDDFPSGLDGESEEDGAKPKSKIPIKAPPQRTEWHPSHPDISLQKSGVPQGQDVLSRGPDGRSKSESDASSLDAKTKCPVKARSYIETETESRERAEGFE-SESEEGATKPKLFASRLPVKSRSTSSSSRTGTSPTRESREHFFDLYRNSIEFFEEISDEASKLVDRLTQ--SEREQEPPSDDESSSALEVSVIENLPPVDTEHSAPEDIFDTRPIWDESIETMIERIPDENGHD-RAEDPQDEQERMEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTVLIECLTKINRMDIVHLLETNTEP-LQERMGRTYAEMEQTITLDHSEGFSVLPEELCAVKEKK--EQEASKESESSDHP-----------------------------------PMVSEEDISVGYSTFQDCIPKT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGDSPAAALSPQMHQESVQQDFSGKMQD---------QQEYYVTTPG----------------------------------------------------------------------------------------------------------AEVEDTQKATVIPDSLCKTPEDISTPPEEAKPCLQTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIEHA-SPIVQEPEEASEPKEESSPRKTSLVIVESTDDQPQVFEKLDGDAAFQKGDDMPDIPPETVTEEEYV---------------------------------------DENGHTVVKKVTRKIIRRYVSSD--------------------GTEKEEITMQGMPQEPVNIEDGDSYSKVIKRVVLKSDTQLSEVTLSEPSIVSGTSQ--FQAEPVEGRRVSKVVKTTMVHGERMEKSLGDSSLATDLPSAKEDFEEVQKEALVHFVFVFLSCLLCVCFMCISWLLWVQKENHLSLLHFMHRSMDGVRVTQKTRFPS-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8R3-1", "uniprot_id": "ANK2_MOUSE", "id": "Q8C8R3-1", "name": "Ankyrin-2", "aln": "-----MMNEDAAQKSDSG-----EKFNGSSQRRKR-------------------------------------PKKSDSNASFLRAARAGNLDKVVEYLKGG--IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYG-ASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG-KNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLG-YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT--EEVTTTTTTITEKHKLNVPETMTEVLDVS------------------DEEGDDTVTGDGGEYLR-----------------------------PEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPSHQVSALAKEAERNSYR-LSWGTENLDNVALSSSPIHSG------------FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLG---------------------------------PVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGG----DAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQH-HIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRG-LVHQAICNLNITLPIYAKESESDQEPEEEIGMTSEKNDETESTETSVL--KSHLVNEVP--------------------------------------------------------------------------------------------------------------------------------------------------VLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSLKVKELAKAGEEEPGEPFEIVERVKEDLEKVNAILRSGTCMRDEGRARSSQSER-ELEEEWVIVSDEEIQEAKQHAPVEIDEHPCIEVRVDRETKAK--VEKDSTGLVNYLTDDLNSYTSPHEKKPHTAPEKSGETSQASAVGKSSESNKGKATSAEEKQSAQKQLKPGLAIKKPVRRKLKEKQKQKEESSQSSEEKTELKKGSSEESVDEDRGLVPEPLPTAKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPVRVKGKEDVPKRTTPRTHPAVSPSSKS------STSSKAERHSSLSSSAKPERHTPVSPSSKNEKLSPVSPSAKTERHSPVFSG-KPEKHSPGSPSTKNERHSPVSSLKTERHTPGSPSGKTDKRPPVPSSGRTEKHPPVSPGKTEKHLPGSPSIRTPEKPAPGSATGKHEKHLPVSP-GKTEKQP------------------------------PISPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQPQDKSKSRVEKEKGHTVTQREVTQRETQRIESQTAKRGQRFQVSAATESRRFRSTTITVGLRMEDPVRERFERTPIIKTPEVVP-------SVAAEESHRGSE----KIVDEQGDMDFQISPDRKTSTDFSEVIKQELEDNDKYQQFRLTEDTEKAQVHLDQVITSPFNTAFPLDYMKDEFLPALSLQSGALGGSSESLKQEVIAGSPCSSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSEEQIGEAKETTKVGTPTDIHSEKELPITNDITDSSQKQGAGVTRGSEPSTEHSQKEVTQDPHKDVCSK-QDGCPESQSVSLA---SEVFTEKGSCGESQLPLVSSAFKTQSESETQESLTPSEVTKPFPPSDASVKTAEGTEPKPQGAIRSPQGLELPLPNRDSEVLSPMADESLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDSSTPKPAVIHECAEEDDSENG--------------EKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYKKEPRQDGSSSASDPDADYSAEVNDEKQMAGTEGEGEVPVLVTSENRKVSSSSSESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNSSPEEATQFQPIVPKQYTFKMN-EEIQEEPATSE-DKDCKSHLAEDSQTHSADAADGSDGDLNRETTQPETCDGHGCETVSPSNSATPVSLGVQSPEHKDVDKPLAIDKDSLAHQDTCENDREEREFDPSGVESTQADLPNE-SSSLS--SRCAIPEGNESAKEIASPSSPVKVEVTITDQALESMPEDCPIQDSSTTMQTERFAMDVPVSELAETDENSDPQIISPYENVPSSSFFSAEPSKIQTDTCHS-----------------TVVHSPEVYSVIIRSSPEDVVVTNSSNRTVSGEESHCESHDLETESEQKSALWAAQSDAPPLAVAPTASDAASVTGEQASKVIITKTDADADS---------------------------------------------------------------------------WSEIREDDAAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRPYADES--LHFFQIGQESNEEAISEDLKEGATGAEPPQTETTSESLELSEPKEAMDDEGELLPDDVSEEIEDLPASDANIDSQVIISASTETPTK--------------EAVSTAVEEPPTTQRSDS--LSTVKQTPRPAVPGPVG--QLDFSPVTRSVYSGQDDESPESSPEEQKS-VIEIPTAPVDNVPSAESKPQIPIRTLPTLVPAPPSAEDESAFSDDFPSSLDEDSKEGGAKPKSKIPVKAPTQRTEWQPSPTDIPLQKTAVPQGQETLSRAPDGRSKSESDASSLDAKTKCPVKARSYIETETESRERAEGFE-SESEDGATKPKLFASRLPVKSRSTSSSGRPGTSPTRESREHFFDLYRNSIEFFEEISDEASKLVDRLTQ--SEREQEPPSDDESSSALEVSVIESLPPVDIEHSAPEDIFDTRPIWDESIETMIERIPDENGHD-RAEDPQDEQERMEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEP-LQERMGRSYAEIEQTITLDHSEGFSVLPDELCAAKEKK--EQEASKESESSDHP-----------------------------------PMVSEEDISVGYSTFQDCLPKT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGDSPAAALSPQMHQEPVQQDFSGKTQD---------QQEYYVTTPG----------------------------------------------------------------------------------------------------------AEVEDPQKATAVPDSLCKTPEDISTPPEGTKPCLQTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTSERG-SPIVQEPEEASEPKEESSPRKTSLVIVESTDDQSQVFERLDGDAAFQKGDDMPDIPPETVTEEEYV---------------------------------------DENGHTVVKKVTRKIIRRYVSSD--------------------GTEKEEVTMQGMPQEPVNIEDGDNYSKVIKRVVLKSDTQQSEDNNE----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01484-4", "uniprot_id": "ANK2_HUMAN", "id": "Q01484-4", "name": "Ankyrin-2", "aln": "-----MMNEDAAQKSDSG-----EKFNGSSQRRKR-------------------------------------PKKSDSNASFLRAARAGNLDKVVEYLKGG--IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYG-ASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG-KNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG-YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT--EEVTTTTTTITEKHKLNVPETMTEVLDVS------------------DEEGDDTMTGDGGEYLR-----------------------------PEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYR-LSWGTENLDNVALSSSPIHSG------------FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGG----DAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQH-HIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRG-LVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNDETESTETSVL--KSHLVNEVP--------------------------------------------------------------------------------------------------------------------------------------------------VLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELVKAAEEEPGEPFEIVERVKEDLEKVNEILRSGTCTRDESSVQSSRSERGLVEEEWVIVSDEEIEEARQKAPLEITEYPCVEVRIDKEIKGK--VEKDSTGLVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRSSE-KEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSGRT-DKHQPVSTAGKTEKHLPVSPSGKTEKQP------------------------------PVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQPQEKGKVRVEKEKGPILTQ-----REAQKTENQTIKRGQRLPVTGTAESKRG-VRVSSIGVKKEDAAGGK-EKVLSHKIPEPVQ-------SVPEEESHRESEVPKEKMADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDVSTPKPAVIHECAEEDDSENG--------------EKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVSSSS-ESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEV-QFQPVVSKQYTFKMN-EDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKICDGHGCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEELDVSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETFENLPKDCPSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESKTQTDANHT-----------------TSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIKMESQQESTLWEMQSDSVSSSFEPTMSATTTVVGEQISKVIITKTDVDSDS---------------------------------------------------------------------------WSEIREDDEAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYADES--FHFFQIGQESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADLLPDDVSEEVEEIPASDAQLNSQMGISASTETPTK--------------EAVSVGTKDLPTVQTGDIPPLSGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRGDDSPDSSPEEQKS-VIEIPTAPMENVPFTESKSKIPVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKLPVKVPLQRVEQQLSDLDTSVQKTVAPQGQDMASIAPDNRSKSESDASSLDSKTKCPVKTRSYTETETESRERAEELE-LESEEGATRPKILTSRLPVKSRSTTSSCRGGTSPTKESKEHFFDLYRNSIEFFEEISDEASKLVDRLTQ--SEREQEIVSDDESSSALEVSVIENLPPVETEHSVPEDIFDTRPIWDESIETLIERIPDENGHD-HAEDPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEP-LQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHP-----------------------------------PIVSEEDISVGYSTFQDGVPKT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPG----------------------------------------------------------------------------------------------------------TETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYI---------------------------------------DEHGHTVVKKVTRKIIRRYVSSE--------------------GTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEDNNE----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KIE7-1", "uniprot_id": "Q0KIE7_DROME", "id": "Q0KIE7-1", "name": "", "aln": "MTLGDVRVENKIQTRSET-----CAINGMALDNKNGI-----------------------------------IKQNDATISFLRAARSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSK--------SGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHG-ANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRS-AKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQG-KNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNG-YTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLKIVTSTSVINSNIGAIEEKLKVMTPELMQETLLSDSD----------------DESCDDLLDHNHYKYMA-----------------------------TDDLKAN------------------YGQDQKNFD-----TTNTDHDLTDVSVLNKKEILPN----------------EMSCIE-LTEIGHKPDNVVIARSQVHLG------------FLVSFLVDARGGSMRGYRHNGVRIIVPPKACAEPTRITCRYVKPQRVVNPPPLMEGEALVSRILEMSPVDGMFLS---------------------------------PITLEVPHYGTLRKNEREIIILRSDNGESWREHN------LYKDIIG---EDINQTEEFHSDRIVRIVTQNVPHFFAVVSRVRQEVHVIGPDGGTVFSTAVPQVKAIFPPHALTKKIRVGLQAQSVDLVECSKLLGQGVAVSPVVTVEPRRRKFHKAITLSIPAPKACTNSMVNACYGNGNSSSPTLRLLCSISGGQTRATWEDVTGSTPLSFVRDSVTFTTTVSARFWLIDCRNIIDAGRMATELYSHLAKVPFYVKFVIFAKRISQTEAKFSVFCMTDDKEDKTLEQQEYFKEVAKSRDIEVLQNQIVYLEFAGNIVPILKKGEQ-LYTKFQPFCENRLSFSAHIKDQ-EFPHGRICFMTYPMVGPDEVPLKPLCTLNISVDFKTITNHLERDNLHSLNDCINAHGKLNHNENIVFGVKEQQVKKID--------------------------------------------------------------------------------------------------------------------------------------------------ITKACIMSSDIKLIHEADVILDDICSHLGSDWPLLANVLGVSQADIDLVKTEFLLNDSVKQSMAMLQLWLEHGGILTG-----------------------------------------------------------------NVLAEALYKIG---------------------------------------------------------RSDIVEKSFKNAEFGTHQPEK---------------------VLPTAG--------------------IEKDGDYEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QDK6-1", "uniprot_id": "A0A8M9QDK6_DANRE", "id": "A0A8M9QDK6-1", "name": "", "aln": "MAHAAAHLKKAR-ELEQP-----PEIKALAKARERRRRHKERAER---------------------------KRKSDSNTSFLRAARAGNIEKVLEFLKSG--QDISTCNQNGLNALHLAAKEGHVELVEELLERGAAVDSSTKKGNTALHIACLAGQKEVAKLLVKKTADVNSQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSMATEDGFTPLAIALQQGHNQVVSLLLEHDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMIALLLDRGSQIDAKTRDGLTPLHCAARSGHDSAVEILLEKGAPILARTKNGLSPLHMSAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKKANPNARALNGFTPLHIACKKNRVKVMELLVKYG-ASIQAITESGLTPIHVSAFMGHLNIVLLLLQNGASPDVCNIRGETALHMAARAGQMEVVRCLLRNGALVDAMAREDQTPLHIASRLGQTEIVQLLLQHMAHPDASTTNGYTPLHISAREGQVETAAVLLEAGASHSLATKKGFTPLHVAAKYGSQDVAKLLLQRRALLDDAG-KYGLTPLHVAAHYDNQQVALMLLDKGASPHATAKNGYTPLHIAAKKNQTRIASALLQYGAETNALTKQGVSPLHLASQEGHTEMAALLLERGAHVNAATKSGLTPLHLTAQEDRVQAAEILAKHDANIDQQTKLG-YTPLIVACHYGNVKMVNFLLQNGANVNGKTKNGYTPLHQAAQQGNTHIVNVLLQHGAKPNAVTMNGNTALSIAKRLGYISVVDTLKVVT--EEIITTTTMVTEKHKLNVPETMTEVLDVSDEEAQHQTEEELFTEVYMEIEGEDTMTGDGGEYLR-----------------------------AEDLRELGDDSLPG-HYLDGMSYT-------------HNLDRSHETPSHLAYRGEGILIEDMIASHQINKVSAFREHEKDSYR-LSWGAEHLDNVVLTSTLLQSGQSTPCLDHDNSSFLVSFMVDARGGAMRGCRHNGLRIIVPPRKCSAPTRVTCRLVKRHRLASMPPMVEGEGLAGKIIEVGPTGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGTERELVILRSETGESWREHHCEHTEEELNQILNGMDEELDPPEELEKKRICRLITRDFPQYFAVVSRIKQDSHLIGPEGGVLSSTLVPQVQAVFPEGALTKRIRVGLQAQPIGEDLVRKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKS-----PTSDGTN---STPTLRLLCSITGGTTPAQWEDITGSTPLTFINQCVSFTTNVSARFWLIDCRQCQESVNFSSQLYREIICVPYMAKFVIFAKTLDPIEARLRCFCMTDDKMDKTLEQQENFTEVARSRDVEVLEGKPIFADCFGNLVPLTKSGQH-HVFSFYAFKENRLSLFIKIRDSTQEPCGRLSFTKEPRTYRT-LNHNAICNLNICLPVYSKDSDSDQDADEESEKTHEKYYD-GSDSTELSMLQ--IIHDPA--------------------------------------------------------------------------------------------------------------------------------------------------TLASPDLLSEVSDMKQDLIKVSVLLTSEKSSSSN--TGKRLNQAADEEVDEPFEIVEKVKEDLEKVEVILREGTVD--EIGAIGRSVTI--DDEEWVLLSEQDVDEFKSKNITEVQETLVQEVRIIRDTLSSSSPKRDMTGMVSYLSNDLEQCLQEMPVPSSHSHDVDIVQESFKEVVLARG------------------KHRPAEIKKPARKKRKEREFASGSSEDDLERMS--RSQSEESLDEDAIIGGSEYVFGSVPVSPKVVETPIGSIKDKVKALQKKVEEE------------------KVTDSQK--WNSQKVSS-----------------------------------SQRTSYIAETEKSYQYPPK--SPKSPRSQTERLEETMSVRELMKAFQTGQDPSKSKSGLFEHKAITTVTSESSDMTQVTTAFDNQMTVTTQHLHEGIITTVTSEASSSDVVQ------VPVAYN------------------------------AQTAISTQHLQEKFAVENEILQELSTDPNTILHKPVIGDGESLSTTTAQNKDDQAVTTKTIFNLKE-----------EKDLDDRLTKLKTHQHEKPSQEPGRFETEKHVSSELLGNKEIVMLPSEN---------------------------------QSSDVMLIAPTYDGQMAVTTKNEQERD---------LLIVHSEATSSDVIQVPTKFDHQMIVSSQHLQVVNSKILQEPSIDPNTVSSQHLQVAESKILQEQSIDPNTVSSQPLQVAESKILQEQSIDPNTVTSQHLQVVEGKILQEPSIDPNTVAPQHLQVVESKILQEPSIDPNT----------------VQLKPVIGDGDALPTTISSSWSIKNKDEEVVTSKIVLSFEEVHSPEDLLVKPRTIDQHGKPSKKTGSFETEEQQMTSELLRNEDMGLKPEKMYYED-----NIYQNRRLSVEPQISPDRKPSEDFSADIKAELEDNPEYLLFRRTSGGASKRHMMFSDALSSDDEQIQQMAVDPSNSNIITAFATAMVQGESLLQSEVDDRALEGSPDGDKHEAWADSPGGSIGLRTPHSSSGDSEKHEGLAET-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQKSPEILVLSSSTTTKETEDQGNQETTHKTKVLISHERREMGEDDKLYSVTSKISETESTSPHD-----FETESPSLFTETELPSNKDSKIRSSSSSTRTETLSFANTNTLIYDTIKGVKWDSEASAHNMKSDSSSRDSVKLIKTDVITKSEKILEQSQDTPDRPYSLDDLQPATMSDFKIVCRTDSLETTPIREDGSSQKTPDSIEPSPTKESPCQDSLEGSPTGQESGQLSFTEKVFSTNQAFVSDSRENIDIEIGSEQDIQLDSESSQESHETQDMQCLSITLDQRENLLESEDLHDFDVLQRQFTPEEEMFKMAAKIKTFDEMEKDAKVKKVKFDFEQPKEERPPHYSSLDTVLTKESEDKYLENLNESGLLYSSLSDDDYYSPESHKVSGQTSEVLETPDKHEQNHTHLKTVDLQACTDIPYMQKHVDNKEDYDQLHSEYHSKTTDETKTEIELITTPVESKMGFEPDTDADSVSPVESTTSEKVNEPISPIDIVGATAANDLQDESQLYLCDYEEKPG--------------------------------------------------------------ETPGSSPIDLVPWSAGVEDDEAFDAQIEDEEQKILAFSTDRQSHGTTPDTTPGRSPTEEGTP----NPFLFQEGKLFEMTRGGAIDMTKRTMEEEEERLAFFPINEDPSEEFERVNFNIS---------ESDEVASFELPSNDSVNQ---------NTIPEELEAKSDSLNKTGTKSVQPEHLEP--------------IEFS--IQNKPSSP-TDNNVHEDTLISN----------VDTTTYTVTQTIHSEQDLESSDSSVEDEHISVVEMPISTQVST------------IFSSASVHTTREDQFQTSSLMSTSFKDIAAEIEDTTSKPKIAVKAASFD-QILEPGDS----------------IEQNLRPKSEADTG----------------DSEWSMSVAEDPIN---IDRIYTIPKTSFSQMPVSPTETPP--PYTVSSQP----------KLPAEFIQNLDSSNTKCDETK----RDKSSTDLGIDSNLKAIRPPSVG------------DDVFEARPNWEDCVETQMQRISDSTTPEQSKVDWHEDADRKEETLAIIADLLGFSWTELAKELEFNEDEIQHVRAENPNSLQEQSHALLQRWVEREGKHATEDTLIKRLTKINRMDIVHLIEIQMHKSIQEQTSRTYAEIER--TLDHSEALSSVQEDVDSLRVVRRVETSQRHPPAVSEEDL----------------------------------SVASLLDIPSWAETMGNIHSESIHGDLMEELEINQDSFTNPWMFHEIKTESAKEVADEEVSTASEEENQAQFDLSDHKNACLPSSQVSSKSQSEDHQHSTKTSQNVFDFSQVSIARFSSSENSVLSTAEPGQAVPDLLQHTSPVTLEEETQLQEPMYQDESSACADQVSPVYEKSDLESSEKSLDAQLFESNGFSDTMQSLSWRENKPSEADELTPENNQISQNISPSISPGAVVREADEVLSRSDEVNPVVSSVTPDLIKGSPESDQVFFTPDKFSDMNPVPSMQSHIAVEQSFVQSCSEVDSASLESPIYNDNTVLIQEQSDTNTYSQELSEPDVDTRKEQQTLAHEQELYLQKTEALGDHCNDTEDRNCPGKAEPQLDSTTDPFIDDSQDFRNELLSQSETDPDTWIERGTAQLRQTSPFRSDLSQQPEACMPCQHFDIREKSLELETESNKQSVSHEIMTARGLKRPQSESLLSSASQQIEKKHTERCLSESSEPLVLTLKINLALEKAVSQEEILALPLSQDGSDKALPPKEFKRQLSDSVSSRAKSQEKHSARCLSGSSETLMLDELKKTFQPEQPLSDHTVNSEVSVSKLTAESQETFTGEQQSVIEETLVESPKSQIDLSEHAQFFQSETGPDMWIQRETAQMSETSSLCSSDLSPQTPETVINCQHFREKSSELESTSAIKSASKGAVEAKGLRRPQSESFISGATQQSEEKRTDRCFSESSQPLVLTLNIDPALEKVVSQEAILALPLSQDGNTLPYLKDSERLLSDSVMHGSISQKKEGNNSGPCLTDSSEDLVFNMSSSPEKIKKPVQPKQPTSDQTVNNEVSVLSVTASTQDTFIGEQQSAVKETSLDSPKFQTDLSENYELKASEMPKADKPKLVGVISTDQQHEDSDLESFFDCKQTISDYSEAEDDEHWKGTMTLNDQFLTSTIHELQQNTNVRSPSSLVAPDESPRWSVQSSDSEDFEDSQIIHEPSDEGEVRDFSSKASLKTSAETPQELPPRGGAEYNDDDDLRREIEDALGVLSDSSDEDVLTTRIVRRRVIIQGDDVPDISPQSVTEEQYT---------------------------------------DAQGNLVVKKVTRKVIRRCVSSD--------------------GVETEQLRVEGSAQQPVHVAPGDSYSKVMKRTVLKSEGHETEVTFHEKDSISASRG-----ESAAGQEVRQMVQTTVVHGEQLEKHEGNPFLARDLPSARDDFTQALNYFGGFRKVQIPRVVEQEILQPDGSVIRRTRMQKSRTHRRSAVRDAGGQKRVCVEQIDDRSE--PHDNLQHHLHHLIHRYCAQND--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QGU1-1", "uniprot_id": "A0A8M9QGU1_DANRE", "id": "A0A8M9QGU1-1", "name": "", "aln": "MAHAAASIKKARVEMEQA-----PDLKALEKAREKRRRSRERAER---------------------------RRKSDSNTSFLRAARAGNIDKVLEYLKGG--VDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIKYG-AFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRGAQVNVTTKSGLTSLHLAAQEDKVGVGEILVKQGANLDQQTKLG-YTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAITVNGNTALAIARRLGYISVVDTLRVVT--EEIVTTTTTVTEKHKLNVPETMTEVLDVSDEEVRRLVDDGAMSDDSIDFEGDDTMTGDGGEYLR-----------------------------AEDLRELGDDSLPG-QYLDGMNYLRFSLEGGRSDSRLQSLDRSYTPTHQSYYSKHYGIMEDVIYSNQVSSLG--RENEKD-----SWETENLDNIALSSSPAHSGHCSPCHDHDNSSFLVSFMVDARGGAMRGCRHNGLRLIIPPRKCSAPTRVTCRLVKRHRLATMPPMVEGDGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVILRSETGESWKEHHCEYTEEELNQVLNGMDERLDPPEELEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPEVQAVFPEGALTKRIRVGLQTQPMSVDVVRNMLGNKATFSPIVTLEPRRRKFHKPITMTIPVPKSSADPALGSFGGG---ETPTLRLLCSITGGTTPAQWEDITGTTPLTFTNDCVSFTTNVSARFWLIDCRQVQESVNFATLMYREIICVPYMAKFVIFAKTHDPIEARLRCFCMTDDKMDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQH-HVFSFYAFKENRLALFIKIRDNTQEPCGRLSFTKEPRSFRT-LSHGAVCNLNISLPAYSKESDSDQEPDEETSRTLGKYDD-DTETTETSILKTHLIRDSP--------------------------------------------------------------------------------------------------------------------------------------------------ALASPDLLSDVSEMKQDLIKMTAILTTDSSEKAGPMQGDYLGKGVEEVSAEPFEIMEKVKEDLEKVSEILRSGTCEKEESAKTEHRRYR--KDEEWVLLTESEIEEAKMMAAFESQEALLKEVRVNRGSQRPKGARERSGIPIGEVKEYLLDAPASQETSSQQRFTEVVLRRGGRKIVPTMAKD---------------TKAHTTEIKKPVRRKGPQGHTDETQSISTKENIA--SKSAGKASEEDAFLPVPGDQK-KSPVSPVVEETPIGPIKEKVKALQKKVEEEQKGH--------------KKQTSQKPPFKSTEAKT-----------------------------------SVLKDQKTTGLKKTSLPQKQSSSKSPKTEPERLEETMSVRELMRAFQTGQDPSKRKSGLFEHKGP-------SKTEHTTMIKSEAKTTNSQCLPHSSSREVSLDVSR------------PVEHH------------------------------EEKEVFDKDAKE--NQKSHVCKQERSGEGLVFGVESAGQQSSMTTAIAQNVS-KHASDLLPDNGTE-----------NGTFNDSSDSIKLEALVD-SPSASLAEVEAPLSSEES-CKHEGMAETPE---------------------------------TSPESLSLSPQQKASQSILAKASN---------------STADTHKAKTSKVSVSFSAEMKT---KIEQASEATVHHPALS---KAVDEPTKSESMCIPHRKKGVNFGGEQTFVDKDIVSISTKSSKSRKLTKRPSETLESFLSDDESCDGQPTP----TFADSLTLRAATQDHGG----------------LVLPLRHQDSETLSPVADDSFNISHKDS-LEGSPLMEDNSSHKTPDSIEPSP------TKESPCCDSLENSPIEMKSNLA-------FPPTVEQPS-----VTTGPLTSSKAPQIPPD------------------------------SLRNRMLKEQEANVDDDSCEQASLMTSS-------------GKSPLS--------------------------------PDTPSSEEVSYEVNPQP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDPMVLIVPFKASVIPEETVED--------DELKCDLTQRKFTPEEEMFKMAAKIKTFD-----------------------EMEQDAKDKRDSRKDSEASQTLVVSDIGQEIITLFGLVSKHETSSVDDVGFIESKQASEIARSVEPIIKVQPPSPFPAGIHKSPQTAEDIQ-------------QTMAHSAASSDESAMRRPQSVTEKHTIK----------PHPQESHSEKFNQECVKSELAELN------------------------KTASSRSNLAANITDEQKEQSLAKQKINESEEIY-----SHEMQNQAANFQNVDKLAS--------------QEERN---------VTDEIKGDYMR-----------------------------------------------------------------------------HAGTSYDDSCSSSLNIDSMPVIIGQNKETFKPEICIYDDTEEDDGEEEPPKTESRGVTAKAETDS----------------------------------------------------------------------------------------WNSMREDDEAFAARVKEEEQKILGLVVDRHSQGATPDTTPARTPTEDGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYEEE--GFAFYQIEHPIMEGVAEEGGNESGGASGDAEKEVGCNLSLQIKAEEEEDQ---------PKVAADLSVRSATAKQSDLSKPKTPIKTD--------------SEKGQGVSEKVEIK-SDKVISEGHLISDSGSSDTVIASIQTAVSTVTRSVHSQQEQESSDSSPEDQHS-VIEQPKTPEK-----------------KESHGKLGSKIHTAASPSTTSKKNMSSSKEEEKPKSRIPVKANSLRSELLEPAKDK----------KSKLPIKPQSRRKSDTDTGPLIPTITKSSKAKSFCESDSSKKPAKKDQNRPTSTDLSSTTKTLPSRLPVRGKPGQP--IQTSTPAKQKKGRPTHTNKEPVVFFEEISQEAAKVVESLAQAEKDKQEAAVLSDDESSTIDVSVIENEPFLDMKMPFPEDPLVIRPRWDNPVETQMERIPADKVR--SQVDPQDEADRKESRLAVIANHLGFSWSELARELEFSDVQINQIRNENPNSLQDQSHALIRLWKEREGKNASENSLMKTLTKINRMDIVHLIETKIIQSSQDHSSHTYAEIEQTISLDHSEGFSALQEDMDSPRSGRRADVSQRRSELVP--------------------------------------VVASIEDLSLNASSLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSQ---------------------------------------------------------------------------------------------------------------------------------------------------KELPDKVTS------------------------------------------------------------------------------------------------------------------------------------------SVVVGDSTHSFEMVGLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQFP----------GTIKQEIAEELGLLSDSSEEEVLTTRVVRRRVVIQGDDMPEIPPQTVTEEQYT---------------------------------------DEYGNMVVKKITRKVIRKYVSAD--------------------GVEREEVMLEGPQQEAVTVDEADSFSKVVKRTVVRSGGDQTEVTFSEPLSYAGATSSKFEEEPVQGRKVSKVVKTMVVQGDRMEKLIGDPSLSSDLPSAKDDFEKALSYVEGFEKVLLPHLVEKETVKEDGSVVRRTRMHKTRTQKRTVVKD-GEAKQTHLERLEDTAESLRPDDLQQHLHQLLQRYCTPEPHPPAGQQDKPQPPPAGRPDA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70511-1", "uniprot_id": "ANK3_RAT", "id": "O70511-1", "name": "Ankyrin-3", "aln": "MAHAASQLKKNRDLEINA----EEETEKKKKHRKRSRDRKK---------------------------------KSDANASYLRAARAGHLEKALDYIKNG--VDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHG-ASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAG-KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG-YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVVT---EEIMTTTTITEKHKMNVPETMNEVLDMSDDEVGK--------ASAPEKLSDGEYISDGEEG------------------EDAITGDTDKYLGPQDLKELGDDSLPA-------EGYVGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLPFTREFDSDSLRHYSWAADTLDNVNLVSSPVHSG------------FLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLG---------------------------------PVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLSELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKG---DTTPSLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQ-LVFNFYSFKENRLPFSIKVRDTSQEPCGRLSFLKEPKTTKG-LPQTAVCNLNITLPAHKKA---------------EKADRRQSFTSLALRKRYSYLTEPSMKTVERSSGTARSLPTTYSHKPFFSTRPYQSWTTTPITVPGPAKSG--SLSSSPSNTPSASPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTISSPIRTVASPSPYNTQVASGTLGRVPTITEATPIKGVAPNSTLSSRTSPVTTAGSLLEKSSITMTPPASPKANITMYSSSLPFKSIITSAAPLISSPLKSVVSPTKSAADVISTAKAAMA------------------------------------------------------------------STLSSPLKQMSGHAEVALVNGSVSPLKYPSSSALINGCKA--TATLQDKISTATNAVSSVVSAAPDTVEKALSTTTAMPFSPLRSYVSAAAPSAFQSLRAPSASALYNSLGPSVGVTTSSVTSSIITVPVYSVGNVLAEPALKKLPDSNSLTKSAAALLSPIKTLTTETRPQPHFNRTS-----------SPVKSSLFLASSALKPSVPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEE-KPFQTDLPREGRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVESKGPPKSPKSDKGHSPEDDWTEFSSEEIREAR-QAAASHAPSLPERVHGKA--------NLTRVIDYLTNDIGSSSL---TNLKYKFEEAKKEGEERQKRILKPAMALQEHKLKMPPASMRPSTSEKELCKMADSFFG-TDAILESPD--------DFSQHDQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEVVHVIRSYEPSTGEIPQSQPEDPVSPKPPPTFMELEPKPTALSIKEKVKAFQMKASSEEEDHSRVLSKGMRVKEETHITTTTRMVYHSPPGSECASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAMSPDVAKSAAETSAQHAEKDNQMKPKLERIIEVHIEKG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQN-----------------------------------------------------------------ETPSGSLESPAQARRITGGLLDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDDSSDQVRDP----------------------------------------------------------------------------------------------------------------------------------------ITSYLTGEAGKFEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGNH-AEVIPEAKAKAYFP------ESQNDIGKQSIKENLKPKTHGCGRAEEPVSPLTAYQKS--------------------------------------LEETSKLVIEDAPKPCVPVGMKKM-------TRT-PADGK-----ARLNLQEEEGSA--RSEPKQGEGYKVKTKKEIRNVEKKAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12955-3", "uniprot_id": "ANK3_HUMAN", "id": "Q12955-3", "name": "Ankyrin-3", "aln": "MAHAASQLKKNRDLEINA----EEEPEKKRKHRKRSRDRKK---------------------------------KSDANASYLRAARAGHLEKALDYIKNG--VDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESK--------SGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHG-ASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAG-KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG-YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVT---EETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRK--------ANAPEMLSDGEYISDVEEG------------------EDAMTGDTDKYLGPQDLKELGDDSLPA-------EGYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPIHSG------------FLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLG---------------------------------PVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKG---DTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQ-LVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKG-LPQTAVCNLNITLPAHKKETESDQDDE------IEKTDRRQSFASLALRKRYSYLTEP--GMIERSTGATRSLPTTYSYKPFFSTRPYQSWTTAPITVPGPAKSGFTSLSSSSSNTPSASPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAVTEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIITSAAPLISSPLKSVVSPVKSAVDVISSAKITMA------------------------------------------------------------------SSLSSPVKQMPGHAEVALVNGSISPLKYPSSSTLINGCKA--TATLQEKISSATNSVSSVVSAATDTVEKVFSTTTAMPFSPLRSYVS-AAPSAFQSLRTPSASALYTSLGSSISATTSSVTSSIITVPVYSVVNVLPEPALKKLPDSNSFTKSAAALLSPIKTLTTETHPQPHFSRTS-----------SPVKSSLFLAPSALKLSTPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEE-KPFQPELPKEGRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVDNKGSPKSPKSDKGHSPEDDWIEFSSEEIREARQQAAASQSPSLPERVQVKAKAASEKDYNLTKVIDYLTNDIGSSSL---TNLKYKFEDAKKDGEERQKRVLKPAIALQEHKLKMPPASMRTSTSEKELCKMADSFFG-TDTILESPD--------DFSQHDQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEVVHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMELEPKPTTSSIKEKVKAFQMKASSEEDDHNRVLSKGMRVKEETHITTTTRMVYHSPPGGEGASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPDVHKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQAEPTEVIIRETKKHPEKEMYVYQKDLSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELTAEESLPSYLESSRVNTPVSQEEDSRPSSAQLISDDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSREKIATAPKKEILSKIYKDVSENGVGKVSKDEHFDKVTVLHYSGNVSSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLNDELQSPEKKARPKNGKEYSSQSPTSSSPEKVLLTELLASNDEWVKARQHGPDGQGFPKAEEKAPSLPSSPEKMVLSQQTEDSKSTVEAKGSISQSKAPDGPQSGFQLKQSKLSSIRLKFEQGTHAKSKDMSQEDRKSDGQSRIPVKKIQESKLPVYQVFAREKQQKAIDLPDESVSVQKDFMVLKTKDEHAQSNEIVVNDSGSDNVKKQRTEMSSKAMPDSFSEQQAKDLACHITSDLATRGPWDKKVFRTWESSGATNNKSQKEKLSHVLVHDVRENHIGHPESKSVDQKNEFMSVTERERKLLTNGSLSEIKEMTVKSPSKKVLYREYVVKEGDHPGGLLDQPSRRSESSAVSHIPVRVADERRMLSSNIPDGFCEQSAFPKHELSQKLSQSSMSKETVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPDSLEFSPGKESPSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVKKIISQECKTVQETRGTFYTTRQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEEVSYEFTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAVEREMPNDVSKDSNQRPKNNRVAYIEFPPPPPLDADQIESDKK-HHYLPEKEVDMIEVNLQDEHDKYQLAEPVIRVQPPSPVPPGADVSDSSDDESIYQPVPVKKYTFKLKEVDDEQKEKPKASAEKASNQKELESNGSGKDNEFGLGLDSPQNEIAQNGNNDQSITECSIATTAEFSHDTDATEIDSLDGYDLQDEDDGLTESDSKLPIQAMEIKKDIWNTEGILKPADRSFSQSKLEVIEEEGKVGPDEDKPPSKSSSSEKTPDKTDQKSGAQFFTLEGRHPDRSVFPDTYFSYKVDEEFATPFKTVATKGLDFDPWSNNRGDDEVFDSKSREDETKPFGLAVEDRSPATTPDTTPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTSEGKSGDQGEGDKSMVTATPQPQSGDTTVETNLERNVETPTVEPNPSIPTSGECQEGTSSSGSLEKSAAATNTSKVDPKLRTPIKMGISASTMTMKKEGPGEITDKIEAVMTSCQGLENETITMISNTANSQMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAPTCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKDTFPPNHMSNTKASKMKQVSQSEKTKALTTSSCVDVKSRIPVKNTHRDNIIAVRKACATQKQGQPEKGKAKQLPSKLPVKVRSTCVTTTTTTATTTTTTTTTTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKMQSELSDEEESTSRNTSLSETSRGGQPSVTTKSARDKKTEAAPLKSKSEKAGSEKRSSRRTGPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQN-----------------------------------------------------------------ETSSGNLESCAQARRVTGGLLDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDDSPDQCRDS----------------------------------------------------------------------------------------------------------------------------------------ITSYLKGEAGKFEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGSH-TEITPEAKTKSYFP------ESQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAYQKS--------------------------------------LEETSKLIIEET-KPCVPVSMKKM-------SRTSPADGK-----PRLSLHEEEGSS--GSEQKQGEGFKVKTKKEIRHVEKKSHS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G5E8K5-1", "uniprot_id": "ANK3_MOUSE", "id": "G5E8K5-1", "name": "Ankyrin-3", "aln": "----------------MS----EEPKEKPAKPAHRKR-KGK---------------------------------KSDANASYLRAARAGHLEKALDYIKNG--VDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESK--------SGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHG-ASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAG-KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG-YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVVT---EEIMTTTTITEKHKMNVPETMNEVLDMSDDEVRK--------ASAPEKLSDGEYISDGEEGDKCTWFKIPKVQEVLVKSEDAITGDTDKYLGPQDLKELGDDSLPA-------EGYVGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPVHSG------------FLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLG---------------------------------PVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKG---DATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQ-LVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKG-LPQTAVCNLNITLPAHKKA---------------EKADRRQSFASLALRKRYSYLTEP----------------------------------------------------------------------------------------------------------------SMSPQ-----------------------------------------SPCERTDIRMAIVADHLG-----------------------LSWTELARELNFSVDEINQIRVENP------------------------------------------------------------------NSLIS------------------------------------------------------------------------QSFMLLKKWVT----------------------RDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGN------------ISGTRSFADENN----------------------------------------------------------------VFHDPVDGH-PSFQVELETP-------------------------------MGLYCTPPNP-----FQQDDHFSDISSIES-------------------------------------------------------PFRTPSRLSDG-------LVPSQGNIEHPTGGPPVVTAEDTS-LEDSKMDDSVT-----VTDPAD--------PLDVDESQLKDLCQSECAQCWASVPGIPNDGR---------------------------------------QAEPLRPQTRKVG-------------------------MSSEQQEKG-------------------------------------------------KSGPD------------EEVTEDKVKSLFEDIQLEEVEAEEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDQGQAMLNRVQRAELA--------------------------MSSLAGWQN-----------------------------------------------------------------ETPSGSLESPAQARRLTGGLLDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDDSSDQARDS----------------------------------------------------------------------------------------------------------------------------------------ITSYLTGEPGKIEA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGNHTAEVIPEAKAKPYFP------ESQNDIGKQSIKENLKPKTHGCGRTEEPVSPLTAYQKS--------------------------------------LEETSKLVIEDAPKPCVPVGMKKM-------TRT-TADGK-----ARLNLQEEEGST--RSEPKQGEGYKVKTKKEIRNVEKKTH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GX00-1", "uniprot_id": "A0AC58GX00_DANRE", "id": "A0AC58GX00-1", "name": "", "aln": "MAHAASQLKKKADLELTA----AEE-EKKKKSRKRTRDPKK---------------------------------KTDSNASYLRAARAGNIEKALDYIKTG--VDINICNQNGLNALHLASKEGHVEVVTELIKLGATVDAATKKGNTALHIASLAGQADVVKELVNNGANINAQSQNGFTPLYMAAQENHLDVVKFLLDNGSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADIESKMMVNRTTESGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNANMVRLLLERGARIDARTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLIHHEVPVDDVTNDYLTALHVAAHCGHYKVAKVLVDKRANPNAKALNGFTPLHIACKKNRIKVMELLLKHG-ASIQAVTESGLTPIHVAAFMGHENIVTQLTNHGASPNTMNVRGETALHMAARAGQANVVKFLVANGADVDAKAKDDQTPLHISSRLGKPDIVQQLLQHGALPDSTTTSGYTPLHLAARDGHKDVASILLDNGASLGITTKKGFTPLHVAAKYGKMEVANLLLQKRAPPDAAG-KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMEIATTLLEYGADTNAATRQGISPLHLAAQEGNVDMVTLLLAREAAVSLGNKSGLTPIHLAAQEDRVNVSEVLVNHGATVDPETKMG-YTPLHVACHYGNVKMVHFLLKNQAKVNAKTKNGYTPLHQAAQQGHTHIINLLLQHGASPNELTVNGNTALAIARRLGYISVVDTLKAVT---EETHTTVTVTEKHKMNVPETMNEVLDMSDDEVRR--------ANVPEMLIED-YISDVEEG------------------EDAMTGDTDKYLGPQDLRELGDDSLPQ-------EGYVGFSVGARTASLRSFSSDRSNTLNRSSFARDSMMIEEILAPTKDTHLALAKDYNTDSMRRYSWTPDTMDNVNLVSSPVHSGFSRSPLQYDNR-FLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLASLPPMVEGEGLASRLVEVGPAGAQFLG---------------------------------PVIVEIPHFGSMRGKERELIMLRSENGETWKEHHYDCKTEDLNELLNGMDEELDSSGDLEKKRICRIITKDFPQYFAVVSRIKQESNQMGPDGGVLSSMTVPMVQASFPEGALTKKIRVGLQAQPVPDEAVKKIIGNRATFSPIVTVEPRRRKFHKPITMIIPVPPVSGEGVVNGYQG---DTTLSLRLLCSITGGTSPAQWEDITGTTPLTFMNDCVSFTTNVSARFWLADCHQTPETVPLATQLYRELICVPYMAKFVVFAKMNDPVESNLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLIKAGQQ-LVFNFYAFKENRLPFCVKVRDNSQEPCGRLSFLREIKTSKG-LAQTAICNLNITLPGFKKDVDSDPEEE------TEKPERRHTFASLALRKRYSYLTEPGTKTVERS--TTRTLPAGYTHKPVFSTRSYQAWSTAPITVPGQTKCGLGSLSSSPSNTPSASPLKSVWSISSASPVKSTLGTSNASPAKSISDVASPIRTYRSMSSPIKTVVQQPQNQVPISSSLLS-SPGKTGTDPVSIKGLAASLSSRANLISSPGSMLDRTFTTVTQSDSIKSTTNTYTS---FKSTLAPTSIAVSSPIRNISS-LSSIKSTTDAARGTFL------------------------------------------------------------------SSLSSSAKPTTASTETVMLNGSVSPLKYPISSSSSSRLFSGGAYSLQERIQATTQAATASVGAAFSEAERTVTGGSKSNYSTLKSVSS--------PLRSHLTSSVYESLRSPVTTTTP-MTSVSMSVPVFSVVSVLPETQGRKLPEKITITP-----QTHNQTQSSTTRKKP-------------------AKPSLFISPTVLKAAATPTLTSNQEILKDVADMKEDLMRMTAILQTDSSTSPKSFHSKVSKEPKIEDEETFSLVEKVKEDLVKVSEILKKDVLSEAKNSRKER------ASEDEWEEFSKDEIEEAR-HSALRSLPTFESTLPVGPQSVPDKDLNLAKVVDYLMNDLGASSLSKIADVKSRYDEIKKEGEEKQKRTMKP-----EHKLKMPPTGMRTSPSEKDLSKLTQETYSGTDAILESPD--------DFS-HEQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPPFTDVPIPPVITETRTEVVHVIRSYE------QPDEVCEPLMDEAAALKPPVEPESAVSSINDKVKALQMKVSSDE---------LACLKEETHITTTTRMVYHKPQLKDAGSDRIEETMSVRDIMKAFQSGRDPSKELAGLFEHKAGQDTIKGD---ELSPRFLEKD--KKPKVERIIEVHIEKGNTNDPTEVIIRETKKHPEFICKSDRGLRELVERVDG-------------DYEVLQDEEELTAEETLPSFLDTSRVNTPVSQEEESRPSSAQLITDESYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDICHSDTEDSVADQTHSIATEVQGAEG-VYGEKVTGPRKESKLRSARDASEKSGKYPPQEEQFDKVTVLHYTTEPGSPKHAVWMRFTQDRQDRNREKLIYEDRVDRTIKEAEEKLSEVSQFFRDKTEKLNDELQSPEKKKPTRLSRETLSGPSSMCSSPE-------KKQKSTADEWEKGRQKMFGSTAERKSASLPNSPERHKLSQFSEDKPKQHESPQQAKTGNTG----PPVPVKTSKVSSFRQKFETEAQKQDKNIPIAQSKKSPESKLPVYQFFTGSKP------------------------------------------------------------------------------------------------------SKSDSADVGQSPSRKLTEIDKSKVDPQSCKSQGPQRTTVSKQSGEKALLEKSTTSNNVAKKASLFEKIKDQGLDTTLESSTKVQDLKDGYSADRHSAVNDIKEQRYLKSDIKNDSFKTDALSKDNVSRNDSQIKTLKKKTESHIPMRTTSSSLDNNQSKKMNQDTVSKSSERSPSHIPTLTRPRVQGRLELQKEDASTTKPEEVSVESKTSDTSSVEKFTVTTRESFKGLKTLPVYVSVQMGKQSDKDMGGG------TNGTIKKVSGSESRTVYAVKQKQPTSPQGSPDDDTLEQFSFIDSSGKSPMTPETPSSEEVSYDLTSRTPDPFIAFMPGITSPIAEVSEESEDSEQGKDHSLKKSGPE----------------VQETKDKRVAYIEFPPPPPLDSDSSQPEKKGSTPSSEAETEMMEVNLQEEHDKHLLAEPIIRVQPPSPVPPGANDSDSSDEESVFKPIPIKKYTFKIDENQDLTDSQSKKQDKNGNDKEPGEN-----------GNGKTEDYDYEQNGNDQSITDCSIATTAEFSHDTDATEIDSLDGYELQDEDDGLSEPIAKPFGFPNDNRKDIWASDNMSRPSDRCQSKLEVIQEE-------------SPAEDCKKTKAKIDPSNRTNGKDEKDGKQSDQGLSDTYFSYKLDEEFNTPFKTVATKG--FDPWSSKGGEDEVVDARIKDDEPKPFGLAVDDKSAATTPDTTPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTFGGRIGNGVRKPNVVTSNSQIVERAQVKLEDNTVMSYNIIQICTDHSDTSHDMEPPPYSEVSSLCSSFKIG--------------------------LKSSNVERRDLVCVDWDSSQGTLPVTAHLIGPETQRTSEYNQRTDSSRAESREYLKTTGNNSRNCSNNVNLEALNARTDCLLQSIVQTEHMSVTDLSSVQVKNACEDLVRKDAGTCRDHSLENSNLISKCKDDIRKPTKSMLPVRAPHAPLSCKKDQTSLRPIQKIKVEARNRLDPFPDVKPKSRIPIMKVKNISSSPVRKCRTTTMAKQKVKPLPIKAITTDKNTKPGLVSTSGSKYGHKPLRDVGKSSHSKPRSVVKVVG------CLSSDDKKIQTYDHDEESSTSRNTSLSEALESSSTSRSARDVRSQVEQSGRDRRRRSRRTEGSQGAGPQVAPGVEIEPSPQTPCERTDLRMAIVADHLGLSWTEMAREMEFSVDEINQIRVENPNSLTAQSFMLLKKWVNRDGKNATTDALAAVLTKINRLDIVTLLEGPIFDYGNISGTRCFADDSAVSQEQADGYHNIELELKSPTELNYEPPTPLRHDDFFSEDSMLKFSSSAPVRPSELSLPTSSGPVSTDTKPPTVTAEDTTIGGRESVAQEDGSAEDDLGVN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QELISPSKQHDSEETSKESDVFPSSPVKEKDAQPMLPICASASEAVKECGKSGFDEEDEEMTQDKIKSLLETIKLEEGSEDEEMTEERLQAI-----------------------------------------------LSQVQQAEKDMSSISGLQSETSGANGKTTTGQGLGTEKQGQRETSQELKS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMPGVQAERQNGEHPEVLSPDASESSSKPKGKARKDSEREEASREVLEDRGPNNREEGISEPKVQQEALRENDSSTDEEETVTTRVYRRRVILKGDQAKNIPGETVTEEQYTDEDGNLVTRKVIRKVVRRSAGVE-------EKGKRKRGKRSRQASRAELEEESGPGPHREHTEAGEGGKGK-KKEGRQKEKKGQS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JII7-1", "uniprot_id": "A0AC58JII7_DANRE", "id": "A0AC58JII7-1", "name": "Ankyrin-1", "aln": "MAQAAKHLRKNKDLEALAEQERKEKEEEKSKKRSRSREKKRKAHVVHRWLIDQDNSVSSELPDGQ--GVWHYDETADAATSFLRAARSGNLEKALDHIKNG--IDINTANQNGLNGLHLASKEGHVKMVLELLHHGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLDNGANQTIPTEDGFTPLAVALQQGHENVVALLINHGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK--------TGFTPLHIAAHYENLNVAQLLLNRGADVNFTPKNGITPLHIASRRGNVIMVRLLLDRGAKIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHLDCIRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNTRALNGFTPLHIACKKNHMRVMDLLLKHS-ASLEAVTESGLTPLHVSSFMGHLNIVKILMQKGASPNASNVKVETPLHMASRAGHCEVAEFLLQNAAPVDAKAKDDQTPLHCASRMGHNEMVKLLLEHKANSNSTTTAGHTPLHIAAREGHTQTASILLDMNAQLTKMTKKGFTPLHVAAKYGKVDVAVLLLERGANPNAAG-KVGLTPLHVAVHHNNLDVVNLLLSKGGSPHSAARNGYTPLHIASKQNQAEVASSLLQHGASANAESLQGVTPLHLASQEGQPDMVLLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKHGASVYAATRMG-YTPLHVACHYGNIKMVKFLLQQQANVNCKTRMSYTPLHQAAQQGHTDIVTLLLKHGAQPNEVTSNGTSALAIAKRLGYISVIDVLKLVT---EETV-TMTTTEKHRMSFPETVDEILDVSEDEG------------IAQLTLGEELLGNEGARYL---------------------------MKMEDIKDHDEDFLSP-------KKVLEN---------HSPAIPR-----IPCVSPETVMLKEHEMEQQHTPLPLPKEYDEDSLIPSSPATETSDNVSPVASPIHTG------------FLVSFMVDARGGSMRGSRHNGLRVIIPPRTCAAPTRITCRLVKPQKLPTPPPLVEGEGLASRIISLGPASMQFLG---------------------------------PVIVEIPHFAALGRGDRELVVLRSENGSVWKEHRNRYGDEVLETILNGMDEDLESQEELGKKRIRRIISTDFPLYFAVVSRIQQENDLIGPEGGFLSSKLVPMVQATFPETAVTKRVRLGLQAQPVPDELVAKLLGNQATFSPVVTVEPRRRKFHRPIGLRIPLPPSWRESPRDAGEG---DTT-SLRLLCSVIGGTAPAQWEDITGTTKLAYSNDCASFTTNVSARFWLADCPRTAEAVSFANLLYRELSAVPYMAKFVVFAKMNEAREGRLRCYCMTDDKMDKTLEQHENFSEVARSRDIEVMEGMPLYLECSGNLVPIRKAAQQPRCFSFQAFKDNRLPVSVKVRDSSKDPSGFLSFLRKSTKYE--DSQHVLCNLNVTMPPCIKIMGSD--------------ERRRTLTPLALRERYSALNEPA---------------------------------------------------------------------------------------------------------------------------------------------------------MASLSAMERTELKMALIAEQLG-----------------------LSWAELGRELQFNVDEINKIRVENP------------------------------------------------------------------NSLLE------------------------------------------------------------------------QSSTLLNLWAA----------------------REGKRAKMDSLYVALKSIDRVDIVNMMEGQGGPPAGQQGGWEQ-----------------------------------------------------------DASRSRHHDRDHLSPGITNGYGLVVQEELVSPASMQYSLPSP----------------------------------------------LGNEPYWQEVSSMECAPIA-------------------------------------------------------------------------TTEEDTLMEMSEVQVWPSGNSPSIVAVEDSSLECSN-ADDSE------------ALQNRSLGHSRSGTPGGNG-LTPGGLSGS---------------------------------------------------------------------------------------------------------------------------IELLEDQSIGADSDYSAAGMLRLSEGVNISALDRGQGLESSE-----GAVGHQVTNNIKDGSNGGLGEGGG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGTQLEDSISLISGQQRVYARMSESPGLRRRADPGEDRLS----AGSFLSYLQDQGSPGWHSAAEATQNRLASLQCS-----------------------------------------------------------------LPRQAIESMMSSVRATV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSDSKQS-----------------------------------------------------------------------------------------------------------------------------------------------CLGQEALIEPVR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMGHSEIIHGHYQGTQPFEKGL---GFPHRTTNMRAWEDMRLSGQGDEAEDLPGEQVSEEQFT---------------------------------------DEHGNIVTKKIVRKVVRRGKGEEGGQELIIEGLQQDISEPDFDGEQFMSYAVLGRDSKPDVVDVKRGGAQIVKCASLRRVKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PR23-1", "uniprot_id": "A0A8M9PR23_DANRE", "id": "A0A8M9PR23-1", "name": "Ankyrin-1", "aln": "MAQAAKQIRKNKDLQELAAQELREKEEEKIKKRNRSRDRRRKAHVVQRWLVHQDSSLSAEGSSETQGGKWHFDGRADATTSFLRAARSGNLEKALDHIKNG--IDINIANQNGLNGLHLASKEGHVKMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK--------TGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHS-ASLEAVTESGLTPLHVAAFMGHLNIVKSLLQRGASPNASNVKVETPLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAG-KNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMG-YTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVLKLVT---EESV-SMITTEKHRMSFPETVDEILDVSEDEG------------VAQLTLGDELLGMDGARY----------------------------LKLDDLKDQDDDFLSP-------KKTLRDFESGMGTTPYSPAIPR-----IPCVSPETVML------DQHTPVPLPKEYDEDSLIPSSPATETSDNVSPVASPIHTG------------FLVSFMVDARGGSMRGSRHNGLRVIIPPRTCAAPTRITCRLVKPQKLTTPPPLVEGEGLASRIISLGPSSMQFLG---------------------------------PVIVEIPHFASLSRGDRELVVLRSENGSVWKEHRNRYGDDVLETILNGMDEDLESQEELEKKRIRRIISTDFPLYFAVVSRVRQESDLIGPEGGQLASKLVPQVQAIFPDTAVTKRVRLGLQAQPIPDELLTRQLGNQATFSPVVTVEPRRRKFHRPIGLRIPLPPSWRESPRDAGEG---DTT-SLRLLCSVIGGTAPAQWEDITGTTKLMYSHNCANFTTNVSARFWLADCPRTAEAVTFANLLYRELMSVPYMAKFVVFAKMNDAREGRLRCYCMTDDKIDKTLELHENFSEVARSRDIEVMEGMPLHLECSGNLVPVRKATQQPRSFSFQAFRDNRLPVSVKVRDANKEASGFLSFLRKSTKYE--DTQHVLCNLNITMPPCVKGVGSD--------------DRRRTLTPLALRERYSALSEPG---------------------------------------------------------------------------------------------------------------------------------------------------------LAAVNAMERTELKITVIAEQLG-----------------------LSWTELARELQFGVDDINRIRVENP------------------------------------------------------------------NSLLD------------------------------------------------------------------------QSSALLNLWVG----------------------REGKKAKMESLYGALKNIDRSDIVKCLEAQAPPVLPET--LEE-----------------------------------------------------------GACRLVDRDSTLLSPSVVNGYG-LVQEELLSPASMQYSLPSP----------------------------------------------LGVEPYWQEVSSLECAPIA-------------------------------------------------------------------------TTEEDTMLEMSDVQVWPAGVSPSLVTVEDSSLDGSSRADDSEG--------NTLSLPCSSLGRPSSGASGASGSIMELEEEEE---------------------------------------------------------------------------------------------------------------------------EEEIEEDDIQHEPVSASAEKAWASGAVPKANYNGQAGGQRSE-----GKRTDAAAGSSMTSVARGGGKGG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGASSEEKFSVLTG-QQLYAQLCERTGLTRSLEHNGDRLG----SGAFQPYSQEKDS-------------LHSWSQP-----------------------------------------------------------------KPRQTMETMMSSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDHNQS-----------------------------------------------------------------------------------------------------------------------------------------------RVAQEALLTPVC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTGHSEVLRGRLLGTQPFDKGL---GFSHQEGELRAWDQERRKAQKDDPVDLSSDLLHEEQFT---------------------------------------DEHGNVVTK-------------------------------------------LGVDVKKDVQTVKR--------SSLRRVKH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZJ94-1", "uniprot_id": "A0A8I5ZJ94_RAT", "id": "A0A8I5ZJ94-1", "name": "Ankyrin-1", "aln": "MAQAAKQLKKIKDIEAQALQEQKEKEESNRKRRNRSRDRKK---------------------------------KADAATSFLRAARSGNLDKALDHLRNG--VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK--------TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTG-ASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTSMVKLLLENDASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG-KNGLTPLHVAVHHNNLDIVQLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVTVDATTRMG-YTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVT---DETS-VVLVSDKHRMSYPETVDEILDVSEDEGT-----------AHISLTGDELVGSKAERR--------------------------------DSRDVGE------------EKELLDFVPKLDQVVESPAIPR-----IPCVTPETVVIR------SEDQEQASKEYDEDSLIPSSPATETSDNISPVASPVHTG------------FLVSFMVDARGGSMRGSRHNGLRVVIPPRTCAAPTRITCRLVKPQKLSTPPPLAEEEGLASRIIALGPTGAQFLS---------------------------------PVIVEIPHFASHGRGDRELVVLRSENGSVWKEHKSRYGESYLDQILNGMDEELGSLEELEKKRVCRIITTDFPLYFVIMSRLCQDYDTIGPEGGSLRSKLVPLVQATFPENAVTKKVKLALQAQPVPDELVTKLLGNQATFSPIVTVEPRRRKFHRPIGLRIPLPPSWTDNPRDSGEG---DTT-SLRLLCSVIGGTDQAQWEDITGTTKLVYANECANFTTNVSARFWLSDCPRTAEAVHFATLLYKELTAVPYMAKFVIFAKMNDPREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMPLFAELSGNLVPVKKAAQQ-RSFHFQSFRENRLAIPVKVRDSSREPGGFLSFLRKPMKYE--DAQHILCHLNVTMPPCTKGSGAE--------------DRRRTLTPLTL--RYSILSESR---------------------------------------------------------------------------------------------------------------------------------------------------------LGFTSDTDRVEMKMAVIREHLG-----------------------LSWAELARELQFSVEDINRIRVENP------------------------------------------------------------------NSLLD------------------------------------------------------------------------QSTALLTLWVD----------------------REGENAKMENLYTALRNIDRSEIVNMLEGSGRQSRNLK----------------------------------------------------------------PDRRHGDRE-YSLSPSQVNGYS-SLQDELLSPASLHYALPSP----------------------------------------------LCADQYWNEVAVIDAIPLA-------------------------------------------------------------------------ATEHDTMLEMSDMQVWSSGLTPSLVTAEDSSLECSK-AEDSD------------AIP-------EWKLEGAHSEDTQGPELGS---------------------------------------------------------------------------------------------------------------------------QDLVEDDTVDSDATNG------------LADLLGQEEGQRSE------KKSQEVSGTEQDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETEVSLVSGQQRVHARITDSPSVRQVLDRSQARTVDWYKQGSAASYPQEAAQS--------------SWQEE-----------------------------------------------------------------VTQGPQSFQRRIT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIQGPEP-----------------------------------------------------------------------------------------------------------------------------------------------GTLQEYEQVVVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TREHVQRGPPESDSPKA----------GKDPSLWASESAFSQEVQGDELQNIPGEQVTEEQFT---------------------------------------DEQGNIVTKKIIRKVVRQVD-----------------SSGAIDTQQHEEVIVEGPLADPGDLEADIESFMKLTKDHTSTPKP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02357-1", "uniprot_id": "ANK1_MOUSE", "id": "Q02357-1", "name": "Ankyrin-1", "aln": "-------------------------------------MGFC---------------------------------KADAATSFLRAARSGNLDKALDHLRNG--VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK--------TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTG-ASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG-KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMG-YTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVT---DETS-VVLVSDKHRMSYPETVDEILDVSEDE-------------------GDELVGSKAERR--------------------------------DSRDVGE------------EKELLDFVPKLDQVVESPAIPR-----IPCVTPETVVIR------SEDQEQASKEYDEDSLIPSSPATETSDNISPVASPVHTG------------FLVSFMVDARGGSMRGSRHNGLRVVIPPRTCAAPTRITCRLVKPQKLNTPPPLAEEEGLASRIIALGPTGAQFLS---------------------------------PVIVEIPHFASHGRGDRELVVLRSENGSVWKEHKSRYGESYLDQILNGMDEELGSLEELEKKRVCRIITTDFPLYFVIMSRLCQDYDTIGPEGGSLRSKLVPLVQATFPENAVTKKVKLALQAQPVPDELVTKLLGNQATFSPIVTVEPRRRKFHRPIGLRIPLPPSWTDNPRDSGEG---DTT-SLRLLCSVIGGTDQAQWEDITGTTKLIYANECANFTTNVSARFWLSDCPRTAEAVHFATLLYKELTAVPYMAKFVIFAKMNDAREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMPLFAELSGNLVPVKKAAQQ-RSFHFQSFRENRLAIPVKVRDSSREPGGFLSFLRKTMKYE--DTQHILCHLNITMPPCTKGSGAE--------------DRRRTLTPLTL--RYSILSESR---------------------------------------------------------------------------------------------------------------------------------------------------------LGFTSDTDRVEMRMAVIREHLG-----------------------LSWAELARELQFSVEDINRIRVENP------------------------------------------------------------------NSLLD------------------------------------------------------------------------QSTALLTLWVD----------------------REGENAKMENLYTALRNIDRSEIVNMLEGSGRQSRNLK----------------------------------------------------------------PERRHGDRE-YSLSPSQVNGYS-SLQDELLSPASLQYALPSP----------------------------------------------LCADQYWNEVTVIDAIPLA-------------------------------------------------------------------------ATEHDTMLEMSDMQVWSAGLTPSLVTAEDSSLECSK-AEDSD------------AIP-------EWKLEGAHSEDTQGPELGS---------------------------------------------------------------------------------------------------------------------------QDLVEDDTVDSDATNG------------LADLLGQEEGQRSE------KKRQEVSGTEQDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETEVSLVSGQQRVHARITDSPSVRQVLDRSQARTLDWDKQGSTAVHPQEATQS--------------SWQEE-----------------------------------------------------------------VTQGPHSFQRRIT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIQGPEP-----------------------------------------------------------------------------------------------------------------------------------------------GALQEYEQVLVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TREHVQRGPPETGSPKA----------GKEPSLWAPESAFSQEVQGDELQNIPGEQVTEEQFT---------------------------------------DEQGNIVTKKIIRKVVRQVD-----------------SSGAIDTQQHEEVELRGSGLQP-DLIEGRKGAQIVKRASLKRGKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16157-1", "uniprot_id": "ANK1_HUMAN", "id": "P16157-1", "name": "Ankyrin-1", "aln": "---------------------------------MPYSVGFR---------------------------------EADAATSFLRAARSGNLDKALDHLRNG--VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSK--------TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTG-ASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAG-KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG-YTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVT---DETS-FVLVSDKHRMSFPETVDEILDVSEDE-------------------GEELISFKAERR--------------------------------DSRDVDE------------EKELLDFVPKLDQVVESPAIPR-----IPCAMPETVVIR------SEEQEQASKEYDEDSLIPSSPATETSDNISPVASPVHTG------------FLVSFMVDARGGSMRGSRHNGLRVVIPPRTCAAPTRITCRLVKPQKLSTPPPLAEEEGLASRIIALGPTGAQFLS---------------------------------PVIVEIPHFASHGRGDRELVVLRSENGSVWKEHRSRYGESYLDQILNGMDEELGSLEELEKKRVCRIITTDFPLYFVIMSRLCQDYDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATFSPIVTVEPRRRKFHRPIGLRIPLPPSWTDNPRDSGEG---DTT-SLRLLCSVIGGTDQAQWEDITGTTKLVYANECANFTTNVSARFWLSDCPRTAEAVNFATLLYKELTAVPYMAKFVIFAKMNDPREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMSLFAELSGNLVPVKKAAQQ-RSFHFQSFRENRLAMPVKVRDSSREPGGSLSFLRKAMKYE--DTQHILCHLNITMPPCAKGSGAE--------------DRRRTPTPLAL--RYSILSEST---------------------------------------------------------------------------------------------------------------------------------------------------------PGSLSGTEQAEMKMAVISEHLG-----------------------LSWAELARELQFSVEDINRIRVENP------------------------------------------------------------------NSLLE------------------------------------------------------------------------QSVALLNLWVI----------------------REGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLK----------------------------------------------------------------PDRRHTDRD-YSLSPSQMNGYS-SLQDELLSPASLGCALSSP----------------------------------------------LRADQYWNEVAVLDAIPLA-------------------------------------------------------------------------ATEHDTMLEMSDMQVWSAGLTPSLVTAEDSSLECSK-AEDSD------------ATGH------EWKLEGALSEEPRGPELGS---------------------------------------------------------------------------------------------------------------------------LELVEDDTVDSDATNG------------LIDLLEQEEGQRSEEKLPGSKRQDDATGAGQDS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENEVSLVSGHQRGQARITHSPTVSQVTERSQDRLQDWDADGSIVSYLQDAAQG--------------SWQEE-----------------------------------------------------------------VTQGPHSFQGTST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEGLEP-----------------------------------------------------------------------------------------------------------------------------------------------GGSQEYEKVLVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSEHTWTEQPEAESSQADRDRR---QQGQEEQVQEAKNTFTQVVQGNEFQNIPGEQVTEEQFT---------------------------------------DEQGNIVTKKIIRKVVRQID-----------------LSSADAAQEHEEVTVEGPLEDPSELEVDIDYFMKHSKDHTSTPNP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40480-1", "uniprot_id": "HOS4_YEAST", "id": "P40480-1", "name": "Protein HOS4", "aln": "-----------------------MNETTTKQPLKK---------------------------------------RSLSSYLSNVSTRREELEKISKQETSE--EEDTAGKHEQRETLSEEVSDKFPENVASFRSQTTSVHQATQNNLNAKESEDLAHKNDASSHEGEVNGDSRPDD----------VPETNEKISQAIRAKISSSSSSPNVRNVDIQNHQPFSRDQLRAMLKEPKRKTVDDFIEEEGLGAVEEEDLSDEVLEKN------------------------TTEPENVEKDIEYSDSDKDTDDVGSDDPTAPNSPIKLGRRKLVRGDQLDATTSSMFNNESDSELSDIDDSKNIALSSSLFRGGSSPVKETNNNLSNMNSS-----------------PAQNPKRGSVSRSNDSNKSSHIAVSKRPKQKKG--IYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFG-------------------------------DTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFESVDDE------------------------------SEFDDEEDQKILREIKKRLSIAAKKWTNRAGIHNDKSKNGNNAHTIDQPPFDNTTKAKNEKAADSPSMASNIDEKAPEEEFYWTDVT--SRAGKEKLFKASKEGHLPYVGTYVENGGKIDLR------SFFESVKCGHEDITSIFLAFGFPVNQTSRDNKTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYAKN---------------SIMGITNSEEIQLIENAINNYLKKHSEDNNDD---DDDDDNNNETYKHEKKREKTQSPILASR------------------------------------------------------------------------------------------------------------------------------------RSATPRIEDEEDDTRMLNLADDDFNNDRDVKESTTSD--------------------------SRKRLDDNENVGTQYSLDWKKRKTNALQDEEKLKSISPLS-----------MEPHSPKKAK-----------------------------------SVEISKIHEETAAEREARLKEEE----------EYRKKRLEKKRKKEQELLQKLAEDEKKRIEEQEKQKVLEMERLEKATLEKARKMEREKEMEEISYRRAVRDLYPLG--------------LKIINFNDKLDYKRFLPLYYFVDEKNDKFVLDLQVMILLKDIDLLSKDNQPTS----------EKIPVDPSHLTPLWNMLK--FIFLYGGSYDDKKNNMENKRYVVNFDGVDLDTKIGYELLEYKKFVSLPMAWIKWDNVVIENHAKR--------KEIEGNMIQISINEFARWRNDKLNKAQQPTRKQRSLKIPRELPVKF----------QHRMSISSVLQQTSKEPFW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :. . . : : * .: . .: :. :*::. .* . ** : .. .: . :. *.: . : : : .. . ..: . : .::: : * : : : . . :: : :*::: ::. *:. : .: .. *. : . : *. : . . ..: : * . : . *: :. .*:*.** :: : :: . . :: : : :..* : * : . : .* * *:***.*.: :. ::: . : ::* *.:* ::: * ** * .. *. : .:. :*** :: *: :: *::: * . :.:. : .::.. :* : . . : . : .* . . : . * * . : .* * : ... : * :. *:: *: . : .:. : .: .:: . :: . :.* :. *: *::::: * . . :.*: * : : . * .*:. . . * . : * : . . . :* . * .. . : . .* * . .:: . .*: : * . :*:.: :** : ..: * : : ..*: . . .. : . :. : : *: :* : :. .. :: :. ** : : * .: . . *: :. : : . ...:. : :: : :. : *. :: : : .. : : : : *.*: :: :: : . . * : ::*:.. ::: . . ", "identical_positions": 81, "similar_positions": 332, "identity": "1.38%" }, { "cls_id": "homologset.agr.FB:FBgn0011754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31325-1", "uniprot_id": "PHKG2_RAT", "id": "P31325-1", "name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "aln": "MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVS-AERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQVDPNARLTAEQALQHPFF-------------------------------------------------------------------------------------------------------------------------------------ERCKGSQP-----------------------------------WNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPRPFPIIATDLEGDSSAITEDEVTLVRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB30-1", "uniprot_id": "PHKG2_MOUSE", "id": "Q9DB30-1", "name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "aln": "MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVS-AERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQHPFF-------------------------------------------------------------------------------------------------------------------------------------ERCEGSQP-----------------------------------WNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPRLFPIAATELEGDSGAITEDEATLVRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15735-1", "uniprot_id": "PHKG2_HUMAN", "id": "P15735-1", "name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "aln": "MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVT-AERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFF-------------------------------------------------------------------------------------------------------------------------------------ERCEGSQP-----------------------------------WNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QXS6-1", "uniprot_id": "F1QXS6_DANRE", "id": "F1QXS6-1", "name": "phosphorylase kinase", "aln": "MTRDIVLGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQEFAVKIIEIT-AEKMTEQQLEEVKSSTLKEIHVLNLVKGHPSIITLIDSYESTAFIFLVFDLMRRGELFDYLTEKVTLSEKETRSMMRALLEAVQYLHALNIVHRDLKPENILLDDQGHLKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCSMDETHEGYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLISRLLVVEPTLRLTAEQALAHPFF-------------------------------------------------------------------------------------------------------------------------------------CQYQKEDV-----------------------------------RLFSPRKTFKALILTVLACIRMQCRYYRARPLTKELLSRDPYSIRGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQN-TAKIILLGLEDLEN---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13286-1", "uniprot_id": "PHKG1_RAT", "id": "P13286-1", "name": "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform", "aln": "MTR----DEALPDSHSAQNFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVVCTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFF-------------------------------------------------------------------------------------------------------------------------------------QEYVVEEV-----------------------------------RHFSPRGKFKVICLTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFEN-TPKAVLLSLAEEEDF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07934-1", "uniprot_id": "PHKG1_MOUSE", "id": "P07934-1", "name": "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform", "aln": "MTR----DDALPDSHSAQTFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDDGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFF-------------------------------------------------------------------------------------------------------------------------------------QEYVVEEV-----------------------------------RHFSPRGKFKVICLTVLASVKIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFEN-TPKAVLLSLAEEEDF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16816-1", "uniprot_id": "PHKG1_HUMAN", "id": "Q16816-1", "name": "Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform", "aln": "MTR----DEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFF-------------------------------------------------------------------------------------------------------------------------------------QQYLVEEV-----------------------------------RHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFEN-TPKAVLLSLAEEDY---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7D0-1", "uniprot_id": "Q9I7D0_DROME", "id": "Q9I7D0-1", "name": "phosphorylase kinase", "aln": "MAKD-EEDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQPEASSYRFGQLNSSCAGAPNYLYCAPQSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNSALASASSHKTLTAMVYYQQQPQQHQTQQQQQQYQQQQTTQLPVQLQLQHPLLQTGGDGKQSVYAPPTVQLRKQSRFNARKKFQFAILVIRAIIRIRRLRFTAEPLHVEEAIRDPYRVKVLRKVIDGCAFRVYGHWVKKGEGQNRAALFEN-TPRTELHALYINNLSR-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : *** .*: ** :*:**:::***:**.****:.: * .*:*.*:::: : .: .:* :* :*. * *** ** * * :*: :*.****:* :********. *:*:**:**.:** ::* : :* .**************:: :::::****: :* .*:* ::****.***** ::*.* : **.:***:*: ***::***.*.******:*::*** **.*.*.* **** * *. ***: : * *:* * :.::.* **** . .: :..* *: .: * :: .*: : **** :: :*::** ***:********: *******:: .. : ", "identical_positions": 166, "similar_positions": 113, "identity": "28.87%" }, { "cls_id": "homologset.agr.FB:FBgn0011758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63156-1", "uniprot_id": "BARH1_RAT", "id": "P63156-1", "name": "BarH-like 1 homeobox protein", "aln": "----------------------------------------MEGSNG--FGIDSILS-HRAGSPALPK-----------------GDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETS--------------------------------TSRPGAASGPGLDSHLQPG--------------QL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGR------LAAKAG--------EDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY---------------------------------------------------------PQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVPR---------------ILIHGLQGASEPPPPLPPLPGVLPRAAQPR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63157-1", "uniprot_id": "BARH1_MOUSE", "id": "P63157-1", "name": "BarH-like 1 homeobox protein", "aln": "----------------------------------------MEGSNG--FGIDSILS-HRAGSPALPK-----------------GDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETS--------------------------------TSRPGAASGPGLDSHLQPG--------------QL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGR------LAAKAG--------EDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY---------------------------------------------------------PQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVPR---------------ILIHGLQGASEPPPPLPPLPGVLPRAAQPR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE3-1", "uniprot_id": "BARH1_HUMAN", "id": "Q9BZE3-1", "name": "BarH-like 1 homeobox protein", "aln": "----------------------------------------MEGSNG--FGIDSILS-HRAGSPALPK-----------------GDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETG--------------------------------TPRPGGASGPGLDSHLQPG--------------QL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGR------LAAKAA--------EDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY---------------------------------------------------------PQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVPR---------------ILIHGLQGASEPPPPLPPLAGVLPRAAQPR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88181-1", "uniprot_id": "BARH2_RAT", "id": "O88181-1", "name": "BarH-like 2 homeobox protein", "aln": "-------------------------------------MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRS-----------LGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHH------------HLHHGQQPPPPSAPPAQSLQPSPQQQ---PPPQPQS-AAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQE------CNAAHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY---------------------------------------------------------HPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPR---------------VLIHGLGPGGQP--ALNPLSNPIPGTPHPR----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIB5-1", "uniprot_id": "BARH2_MOUSE", "id": "Q8VIB5-1", "name": "BarH-like 2 homeobox protein", "aln": "-------------------------------------MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRS-----------LGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHH------------HLHHSQQPPPPSAVPAQSLQPSPQQQ---PPPQPQS-AAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQE------SNAAHESFRPKLEQEDGKTKLDKREDPQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY---------------------------------------------------------HPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPR---------------VLIHGLGPGGQP--ALNPLSNPIPGTPHPR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY43-1", "uniprot_id": "BARH2_HUMAN", "id": "Q9NY43-1", "name": "BarH-like 2 homeobox protein", "aln": "--------------------------------------MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRP-----------LGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHH------------HLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQE------SNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY---------------------------------------------------------HPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPR---------------VLIHGLGPGGQP--ALNPLSSPIPGTPHPR----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24255-1", "uniprot_id": "BARH1_DROME", "id": "Q24255-1", "name": "Homeobox protein B-H1", "aln": "MKDSMSILTQTPSEPNAAHPQLHHHLSTLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRSVDSCSQSDDEDQIQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ..*.: : .**. . *.. :. . . .. .: :* .. .. * . :.. : * :* : ::: . . . **.*. ::. .. * *: . . . * . .::*: :.* .. . ** *******:**** **:***********:* :** *:*:* *****************************::*:**:: .. : : .. :.. :: * ..*. * :*:.* : *. . * . * . * :. * ", "identical_positions": 90, "similar_positions": 94, "identity": "16.54%" }, { "cls_id": "homologset.agr.FB:FBgn0011760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FJ2-1", "uniprot_id": "DYL2_HUMAN", "id": "Q96FJ2-1", "name": "Dynein light chain 2, cytoplasmic", "aln": "MSDRK---AVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q78P75-1", "uniprot_id": "DYL2_RAT", "id": "Q78P75-1", "name": "Dynein light chain 2, cytoplasmic", "aln": "MSDRK---AVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0M5-1", "uniprot_id": "DYL2_MOUSE", "id": "Q9D0M5-1", "name": "Dynein light chain 2, cytoplasmic", "aln": "MSDRK---AVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q24117-1", "uniprot_id": "DYL1_DROME", "id": "Q24117-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MSDRK---AVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P63167-1", "uniprot_id": "DYL1_HUMAN", "id": "P63167-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MCDRK---AVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02647-1", "uniprot_id": "DYL1_YEAST", "id": "Q02647-1", "name": "Dynein light chain 1, cytoplasmic", "aln": "MSDENKSTPIVKASDITDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVYFYIGPLAFLVFKTA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*.: .::* :*:::.:::* : :.:*::**::*:***. :**::* **. *** ***:*********. **:***:* :*:*:**:.", "identical_positions": 42, "similar_positions": 37, "identity": "45.65%" }, { "cls_id": "homologset.agr.FB:FBgn0011761", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LXI1-1", "uniprot_id": "A0ABK0LXI1_RAT", "id": "A0ABK0LXI1-1", "name": "Thioredoxin", "aln": "-----------------------------------------------------------------------------------------------EQDSVWS--------------LKSPKLLQAP--------ALAPPLETKVLVPR----LRARQPGARPALGQSLSCSSGLFWPRPLETAPPFGGVVWARPAGAPWR------------------------------------------AREARELVPAARARPPRPA--------------------------------ALRP------------VSIKRRRAPHSAASSVG------------CLGSISIGFCRNSCGSLPATA--------------------------------------------------------------------------------------------------------KMVKLIESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSN-VVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFS----------------------GANKEKLEATITEFA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10639-1", "uniprot_id": "THIO_MOUSE", "id": "P10639-1", "name": "Thioredoxin", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVKLIESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSN-VVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFS----------------------GANKEKLEASITEYA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10599-1", "uniprot_id": "THIO_HUMAN", "id": "P10599-1", "name": "Thioredoxin", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSN-VIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFS----------------------GANKEKLEATINELV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P902-1", "uniprot_id": "TXND2_MOUSE", "id": "Q6P902-1", "name": "Thioredoxin domain-containing protein 2", "aln": "--------MTLNNGGKANER----GSNENPLQALSKNEAFLVP------------EFLDTAQSKEKAIASKVSNTLHMSTEESEFPQQVSSTPMFSENTVHPRHEVSPKPSSKNTQLKQENISKSSGYSKQTNYSNTPKSLAKTTHPKQGSTLKPATNSTHYREDDIPKSSEDIIQPKKGDRPKSSEDIIQSKKEDRPKSSEDIIQSKKEDRPKSSEDIIQSKKEDRPKSSEDIIQSKKEDRPKSSEDIIQPKKEDRPKSSEDSVPSKKGDRPKSSEDSVQPKKEDRPKSSEDSVQSKEGEVHKPLKDSIQSKETKVPKSPQDSIQSKEDKTHRPLKDSVQSKESEEPKSSHESIQSKE-DKIHKP--------------LKDSIPSKE-------------GDIPKSPEDTIQSQE-EITASEEDTIQSQEGNTIKSSEEDVQLSESKLLGLGAEIETLEEG-LVRVIKDKEEFEEVLKDAGEKLVAVDFSAAWCGPCRMMKPLFHSLSLKHED-VIFLEVDTEDCEQLVQDCEIFHLPTFQFYKNEEKVGEFS----------------------GALVGKLERSISELK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XHX6-1", "uniprot_id": "TXND2_RAT", "id": "Q5XHX6-1", "name": "Thioredoxin domain-containing protein 2", "aln": "--------MFKKNQKLSKDK----GLEVNSVQAGAPEESDVKLNNGGKANERGSNEFLDTAQSKEKVIASVVGNMLHMSTEESEPPQQVSSTSMFSENTIYPKHEGSPKSSTKNTQLKQEDISKTSSYSKQTNSSNIPKSLAITTYPKQGSTLKPAANGTHDREAEKPKSSEDLIQSKKGDIFKPSEDSIQSKKGDMPKSSEDPIQSKKDDTAKSLEDTIQSKNGDMPKSSEDPIQSKKDDTARSLEDSIQSKKGDMPKSS-DTIQSKESETPKFLQDTIQSKGGKINKQVKDSMKSKESKIRKPLKDSIQSKENKIPKSSQDSAQPKEGKIHKPLKDSLPSKEGDISKPSEDTIQAKE-EITVSPEDTIQAKE-EITMSPEDTIQAKEEITVSPEDTIQAKEEITVSPEDTMQSKE-EITVSPEDTVQSQEGD-IKSSE-DVQPSENEIFPFEAEIETLEEG-MVRVIKDKEEFEEVLKDAGEKLVAVDFSAPWCGPCRKMRPHFHSLSLKHED-VIFLEVDTEDCEQLVQDCEVFHLPTFQFYKNEEKVGEFS----------------------GALVEKLEKSIAELK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VQ3-1", "uniprot_id": "TXND2_HUMAN", "id": "Q86VQ3-1", "name": "Thioredoxin domain-containing protein 2", "aln": "MDVDKELGMESVKAGASGKPEMRLGTQEETSEGDANESSLLVLSSN---VPLLALEFLEIAQAKEKAFLPMVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKE-------------GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHED-VVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELC----------------------GALKEKLEAVIAELK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69AB2-1", "uniprot_id": "TXND8_MOUSE", "id": "Q69AB2-1", "name": "Thioredoxin domain-containing protein 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVKRIKNMSELKELFSDAGNKLVVVEFSAKWCGPCKTIAPVFQAMSLKYQN-VTFAQVDVDSSKELAEHCDITMLPTFQMFKYTQKVTPFSRLKRVLCCLRSGPKSKMIFECHGADAKQLEKKIQELM--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69AB1-1", "uniprot_id": "TXND8_RAT", "id": "Q69AB1-1", "name": "Thioredoxin domain-containing protein 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQKIKSMREFKELLGAAGNRLVVVEFSAQWCGPCKMIAPAFQAMSLQYRN-VMFAQVDVDSSQELTEHCSIQVVPTFQMFKHSRKVTPFSRLKRILCCFRSGPGSKKIFEFQGADIEKLEEKIQELM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47938-1", "uniprot_id": "THIO1_DROME", "id": "P47938-1", "name": "Thioredoxin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVRTMNDYHKRIEAADDKLIVLDFYATWCGPCKEMESTVKSLARKYSSKAVVLKIDVDKFEELTERYKVRSMPTFVFLRQNRRLASFA----------------------GADEHKLTNMMAKLVKA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25372-1", "uniprot_id": "TRX3_YEAST", "id": "P25372-1", "name": "Thioredoxin-3, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFYKPVMRMAVRPLKSIRFQSSYTSITKLTNLTEFRNLIKQNDK--LVIDFYATWCGPCKMMQPHLTKLIQAYPD-VRFVKCDVDESPDIAKECEVTAMPTFVLGKDGQLIGKII----------------------GANPTALEKGIKDL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .. :.::* * *****: : . . : : . . . : *.:. ::. : :*** : : . : : ** * : . ", "identical_positions": 14, "similar_positions": 35, "identity": "2.36%" }, { "cls_id": "homologset.agr.FB:FBgn0011762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LNK6-1", "uniprot_id": "F1LNK6_RAT", "id": "F1LNK6-1", "name": "DNA primase", "aln": "-------------------MELFDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPSQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWTLMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLIKGG---HDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVDQDILEN-KENWDKILALVP-ETVHDELQKGFQR----FHSSPQRWEYLRKVASAPQN-TKNDKCG---PWLEWEIMLQYCFPRLDINVSKGVNHLLKSPFSVHPKTGRISVPIDFQKVDQFDPFVVPTISAICRELDVVSTTEKEKEENETDS--RHRVRDYKRTSLAPYVKVFEQFLENLDKSRKGALLKKSDLQKDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20664-1", "uniprot_id": "PRI1_MOUSE", "id": "P20664-1", "name": "DNA primase small subunit", "aln": "-------------------MEPFDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSELEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWTLMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGG---QDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVGQDILEN-KENWDKILALVP-ETIHDELQRGFQK----FHSSPQRWEHLRKVANSSQN-MKNDKCG---PWLEWEVMLQYCFPRLDVNVSKGVNHLLKSPFSVHPKTGRISVPIDFHKVDQFDPFTVPTISAICRELDMVSTHEKEKEENEADS--KHRVRGYKKTSLAPYVKVFEQFLENLDKSRKGELLKKSDLQKDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49642-1", "uniprot_id": "PRI1_HUMAN", "id": "P49642-1", "name": "DNA primase small subunit", "aln": "-------------------METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGG---QDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILEN-KESWDKILALVP-ETIHDELQQSFQK----SHNSLQRWEHLKKVASRYQNNIKNDKYG---PWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAISTNEEEKEENEAESDVKHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24317-1", "uniprot_id": "PRI1_DROME", "id": "Q24317-1", "name": "DNA primase small subunit", "aln": "MPEQVTDQENQAPQQQTTAVHAYNPEVLQDMLPVYYRRLFPHLPFYRWLSYGSSEDAIFSNREISFTLQDDIYIRYLCFDTQAELEKEICSRNPIKIDIGPVMHSKPKNHRSIP-GGLTPVQRELVFDIDMTDYDEVRTCCSGAGVCLKCWKFMVLAARVLDVALREDFGFEHIIWIFSGRRGIHCWVCDYQARHLDGRGRYAVAEYLNIITYASFAGGNSPRCSMGDRPHHSLKRALKIVEPMFEEIVLEDQNLFGT-PKGVTKLLNMVHDDAARGELESYMQKNLEDGAHSRLVWESFIKYANSMRTSTTSAWSRK-LKNIVAEIQLGLLYPRLDINVTRGFNHLLKAPFCIHPATGKVCVPFSVSAVAKFDPTTVPTITQLLHEINAFDDKSKSYMEAPEDK---SRIKDHKKTSMFKGVVVFEEFLRKLERSQKSASLQF-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10363-1", "uniprot_id": "PRI1_YEAST", "id": "P10363-1", "name": "DNA primase small subunit", "aln": "-----------------MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDR----NTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDN--PRRSSKEKWNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQTIHLLKAPFCIHPATGNVCVPIDES----FAPEKAPKLIDLQTEMEKNNDVSLTALQP--------FINQFQAYVSSLLKNELGSVKREREDDDEPASLDF-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : **: *:*. :.**.:. . : :**::::::.. * ** .*:. ::: :: . ** :::**.: * :: :: . : . ::******** *** .* ***.* :* ***.:: :* :: : **:****::. :*::***** ****.* .* * . * : :*:.:: . . : : * : :::: :: * . * *: . .:* : . ..*: * *: : : *. . .. :: * :*:**::*:: ****:**.:** **.:.**:. * * .*.: : *:: . . : . .: : . .: : . : *. ", "identical_positions": 90, "similar_positions": 134, "identity": "19.96%" }, { "cls_id": "homologset.agr.FB:FBgn0011763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LX68-1", "uniprot_id": "A0ABK0LX68_RAT", "id": "A0ABK0LX68-1", "name": "Transcription factor", "aln": "MTTKNVGLTSTNAELRGFID-------------QNFSPTKGNISLVAFPVSSTNSP--------------------------TKILPKTLGPVNVNVGPQMIISTPQRITNSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPSDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNASNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPAVNSTIQLPFIVINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIAKSLVPKALEGYITDVSTGPSWLNQGLLLNSTQSVSNLDPTTGATVPQSSVNQGLCLDAEVALATGQFLAPNSHQSSTAASQFSESRGETP-CSFNDEEEEDEEEDPSSPE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64163-1", "uniprot_id": "TFDP2_MOUSE", "id": "Q64163-1", "name": "Transcription factor Dp-2", "aln": "MTAKNVGLPSTNAKLRGFID-------------QNFSPSKGNISLVAFPVSSTNSP--------------------------TKILPKTLGPINVNVGPQMIISTPQRIANSGSVLIGNPYTPAPAMVTQTHIAEAAGWVPSDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADS-AYDQENIRRRVYDALNVLMAMNIISSLPTGKKRNQVDCNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPAVNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIARSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDPTTGATVPQSSVNQGLCLDAEVALATGQLPASNSHQSSSAASHFSESRGETP-CSFNDEDEEDEEEDPSSPE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14188-1", "uniprot_id": "TFDP2_HUMAN", "id": "Q14188-1", "name": "Transcription factor Dp-2", "aln": "MTAKNVGLTSTNAEVRGFID-------------QNLSPTKGNISFVAFPVSNTNSP--------------------------TKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADS-AYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETP-CSFNDEDEEDDEEDSSSPE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JXN0-1", "uniprot_id": "A0A0G2JXN0_RAT", "id": "A0A0G2JXN0-1", "name": "Transcription factor", "aln": "-MAKDASLIEANGELKVFID-------------QNLSPGKGVVSLVAVHPSTVNTLG-------------------------KQLLPKTFGQSNVNITQQVVIGTPQRPAAANTIVVGSPHTPNTHFVSQNQTSDS----------------SPWSAGKRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRQAEQQARRPPPPNSVIHLPFIIVNTSRKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKVARSLVPKALEPYVTEMAQG---SIGGVFVTTTGSTSN-----GTRLSASDLSN----GADGMLAT-----------SSNGSQYSGSRVETP-VSYVGEDDDDDDDFNENDEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08639-1", "uniprot_id": "TFDP1_MOUSE", "id": "Q08639-1", "name": "Transcription factor Dp-1", "aln": "-MAKDASLIEANGELKVFID-------------QNLSPGKGVVSLVAVHPSTVNTLG-------------------------KQLLPKTFGQSNVNITQQVVIGTPQRPAASNTIVVGSPHTPNTHFVSQNQTSDS----------------SPWSAGKRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRQAEQQARRPPPPNSVIHLPFIIVNTSRKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGNCSAEDLKVARSLVPKALEPYVTEMAQG---SIGGVFVTTTGSTSN-----GTRLSASDLSN----GADGMLAT-----------SSNGSQYSGSRVETP-VSYVGEDDDDDDDFNENDEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14186-1", "uniprot_id": "TFDP1_HUMAN", "id": "Q14186-1", "name": "Transcription factor Dp-1", "aln": "-MAKDAGLIEANGELKVFID-------------QNLSPGKGVVSLVAVHPSTVNPLG-------------------------KQLLPKTFGQSNVNIAQQVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDS----------------SPWSAGKRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFSAADNHILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQG---TVGGVFITTAGSTSN-----GTRFSASDLTN----GADGMLAT-----------SSNGSQYSGSRVETP-VSYVGEDDEEDDDFNENDEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5H9I0-1", "uniprot_id": "TFDP3_HUMAN", "id": "Q5H9I0-1", "name": "Transcription factor Dp family member 3", "aln": "-MAKYVSLTEANEELKVLMD-------------ENQTSRP-----VAVHTSTVNPLG-------------------------KQLLPKTFGQSSVNIDQQVVIGMPQRPAASNIPVVGSPNPPSTHFASQNQHSYS----------------SPPWAGQHNRKGEKNGMGLCRLSMKVWETVQRKGTTSCQEVVGELVAKFRAASNHASPNESAYDVKNIKRRTYDALNVLMAMNIISREKKKIKWIGLTTNSAQNCQNLRVERQKRLERIKQKQSELQQLILQQIAFKNLVLRNQYVEEQVSQRPLPNSVIHVPFIIISSSKKTVINCSISDDKSEYLFKFNSSFEIHDDTEVLMWMGMTFGLESGSCSAEDLKMARNLVPKALEPYVTEMAQG---TFGGVFTT-AGSRSN-----GTWLSASDLTN----IAIGMLAT-----------SSGGSQYSGSRVETPAVEEEEEEDNNDDDLSENDEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24318-1", "uniprot_id": "TFDP_DROME", "id": "Q24318-1", "name": "Transcription factor Dp", "aln": "-MAHSTGGTVKTDEVNFFFRNEHGQISKMLKPAQNKSEMEGGKPVAVVYATGSSARNSGSASGIGNVGRMGAFSQMGSQGQFIRLQDNGLSIPKTEAGTTYTTVSAQKTSGAGSGHYDLPLKGDRYVKFTPNPIKMKSKLHAIQSNSLHSMSASSSSVQRKRKPDKAGKGLRHFSMKVCEKVEEKGKTTYNEVADDLVSEEMKNN----AYDNNCDQKNIRRRVYDALNVLMAINVISKDKKEIRWIGLPANSTETFLALEEENCQRRERIKQKNEMLREMIMQHVAFKGLVERNKRNESQ-GVVPSPNASIQLPFIIVNTHKSTKINCSVTNDKSEYIFKFDKTFEMHDDIEVLKRMGFLLGLDKGECTPENIERVKSWVPPNLAKYVEAYGTG----KTGENMYESDDEDN---EFNGYLESANESQ-------------------------GFAQHSAQHTTDGEFKLEMDDDELDDDID------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. . ::. :: :* : ... : .. :: : :. ..: .*: : :. . * . : : ::.:* :* * ** ::**** *.*:.**.*: :**..:**:: . . . * :**:**.*********:*:** . : : **:: *. *. :* ******. *:::::*::***.** **: *.* * *: *::***::.: :.* *:**::.** **:*:*:.:**:*** *** **: **:.*.*: *::: .:. ** * *: . * * : . .* . . :. .: :: * .: . :::: ::: ", "identical_positions": 99, "similar_positions": 133, "identity": "20.25%" }, { "cls_id": "homologset.agr.FB:FBgn0011766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACR8-1", "uniprot_id": "D4ACR8_RAT", "id": "D4ACR8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQQRTARKLPSLLVDPAQETVRR-------------------------------------------------RCRDPINVEN--------------------LLPSKIRINLEENVQYVSMR-------------------------------------KALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIELVEKKSKNHIRWIGSDLN-NFGAAPQQKKLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENER-LAYVTYQDIHGIQAFHEQIVIAVKAPEETRLDVPAPREDSITVHIRSTKGPIDVYLCEVEQNHSNGKTADG----------VGASPSDSKHLQSPEKEDKPLQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54917-1", "uniprot_id": "E2F6_MOUSE", "id": "O54917-1", "name": "Transcription factor E2F6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQQRTARRQPSLLVDPAQETVRR-------------------------------------------------RCRDPINVEN--------------------LLPSKIRINLEENVQYVSMR-------------------------------------KALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIELVEKKSKNHIRWIGSDLN-NFGAAPQQKKLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENER-LAYVTYQDIHGIQAFHEQIVIAVKAPEETRLDVPAPREDSITVHIRSTKGPIDVYLCEVEQNHSNGKTNDG----------IGASPSKSSHPQCPEKEDEPPQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75461-1", "uniprot_id": "E2F6_HUMAN", "id": "O75461-1", "name": "Transcription factor E2F6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQQRPARKLPSLLLDPTEETVRR-------------------------------------------------RCRDPINVEG--------------------LLPSKIRINLEDNVQYVSMR-------------------------------------KALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLS-NFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENER-LAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEG----------VGTSSSESTHPEGPEEEENPQQSEELLEVSN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RDX6-1", "uniprot_id": "M0RDX6_RAT", "id": "M0RDX6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAPR----------------TLAPATAQPTKSLPTLNPTELWPSGLS--------SPQLCPATTATTYYTSLYT---------QTVP-SSAALGTCLDATPHGPEG--QIVRCVPA---------GRLPAKRKLDLEGLGRPTVPE-FRTPKGKCIRVDGLP-----------------SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKSKNNIQWVGRGIFEDPTRPAKEQQLGQELKELMNAEQTLDQLIQSCTLSFKHLTEDNANKK-LAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRAEENLQIYLKSTQGPIEVYLCPEEGQEADSPTKEA----------LPSTSTLSPVPDCAQPGCSTDSGLAETIESSVLMPQPVPPPLPPP------PPAPSLVPLEATDNMLELSHPLLQQTEDQFLSPILTASSP--------LISFSPPLDQEEYLWGMDEGEGISDLFDSYDLGDLLIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56931-1", "uniprot_id": "E2F2_MOUSE", "id": "P56931-1", "name": "Transcription factor E2F2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRAPR----------------TLAPATAQPTKSLPALNPTELWPSGLS--------SPQLCPATTATTYYTSLYT---------QTVP-SSVALGTCLDATPHGPEG--QIVRCAPA---------GRLPAKRKLDLEGIGRPTVPE-FRTPKGKCIRVDGLP-----------------SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKSKNNIQWVGRELFEDPTRPSRQQQLGQELKELMNAEQTLDQLIQSCSLSFKHLTEDNANKK-LAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRAEENLQIYLKSTQGPIEVYLCPEEGQEPDSPAKEA----------LPSTSALSPIPDCAQPGCSTDSGIAETIEPSVLIPQPIPPPPPPPL-----PPAPSLVPLEATDNMLELSHPLLQQTEDQFLSPILAANSP--------LISFSPPLDQDEYLWGMDEGEGISDLFDSYDLGDLLIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14209-1", "uniprot_id": "E2F2_HUMAN", "id": "Q14209-1", "name": "Transcription factor E2F2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQGPR----------------ALASAAGQTPKVVPAMSPTELWPSGLS--------SPQLCPAT--ATYYTPLYP---------QTAP-PAAAPGTCLDATPHGPEG--QVVRCLPA---------GRLPAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLP-----------------SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKR-LAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEP----------LPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPP---------PSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSP--------LISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K0V6-1", "uniprot_id": "A0A0G2K0V6_RAT", "id": "A0A0G2K0V6-1", "name": "", "aln": "MAANGKQPVATSLQDWYRSKATAIQWTVGTVLGGLRGGDMQIWFEKPAGNLSFAGGPWRVNRIPSFIVSSSFLEPFFSCRPQHPGCRRRLAIRCIGCPRRLHPSSGPDIRAAGTLLSPDPRLFLAPGACAVRKNKKKREREGSEAPGGEARRRDLETPAANNKEIESNTLIYRNTKKEQEREMRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASSGFAAAAA----PGTYIQILTTNPSTTSCATSLQSGALAAGPLLPSVPGTEPAASSLLYTTPQGPSSRAGLLQQPPAAGRGG---GGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPD----------------SPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQR-LAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIES-LQIHLASTQGPIEVYLCPEET-ETHRPMKTN----------NQDHNGNIPKPTSKDLASNNSG----HSDCSVSTANLSPLASPAN---------------------------LLQQTEDQIPS---NLEGP--------FVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35261-1", "uniprot_id": "E2F3_MOUSE", "id": "O35261-1", "name": "Transcription factor E2F3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAA----PGTYIQILTTNPSTTSCATSLQSGALTAGPLLPSVPGTEPAASS-LYTTPQGPSSRVGLLQQPPAPGRGG---GGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPD----------------SPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQR-LAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIES-LQIHLASTQGPIEVYLCPEET-ETHRPMKTN----------NQDHNGNIPKPTSKDLASNNSG----HSDCSVSTANLSPLASPAN---------------------------LLQQTEDQIPS---NLEGP--------FVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00716-1", "uniprot_id": "E2F3_HUMAN", "id": "O00716-1", "name": "Transcription factor E2F3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPD----------------SPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQR-LAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIES-LQIHLASTQGPIEVYLCPEET-ETHSPMKTN----------NQDHNGNIPKPASKDLASTNSG----HSDCSVSMGNLSPLASPAN---------------------------LLQQTEDQIPS---NLEGP--------FVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O09139-1", "uniprot_id": "E2F1_RAT", "id": "O09139-1", "name": "Transcription factor E2F1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVAPAGGQHAPALEALLGAGALRLLDS--------SQIVIISTAPDVGAPQVPTGP-------AAPPAGPRDPDVLLFATPQAPRP----APSAPRP------ALGRPPVKRRLDLET-DHQYLAGS----SGPFRGRGRHP------------------GKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSRT--MVGIGQRLEGLTQDLQQLQESEQQLDHLMHICTTQLQLLSEDSDIQR-LAYVTCQDLRSIADPAEQMVIVIKAPPETQLQAVDSAET-FQISLKSKQGPIDVFLCPEESAEGISPGRTS----------YQETS--GEDRNAD--SGT-AGPPPSPPSTSPTLDPSQSLLGLEQEAVLPRIGNLRAPMEEDRLSPLVAADSLLEHVKEDFSG---LLPGE--------FISLSPPHEAVDYHFGLEEGEGIRDLFD-CDFGDLTPLDF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61501-1", "uniprot_id": "E2F1_MOUSE", "id": "Q61501-1", "name": "Transcription factor E2F1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVAPAGGQHAPALEALLGAGALRLLDS--------SQIVIISTAPDVGAPQLP----------AAPPTGPRDSDVLLFATPQAPRP----APSAPRP------ALGRPPVKRRLDLET-DHQYLAGS----SGPFRGRGRHP------------------GKGVKSPGEKSRYETSLNLTTKRFLELLSRSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHT--MVGIGKRLEGLTQDLQQLQESEQQLDHLMHICTTQLQLLSEDSDTQR-LAYVTCQDLRSIADPAEQMVIVIKAPPETQLQAVDSSET-FQISLKSKQGPIDVFLCPEESADGISPGKTS----------CQETSS-GEDRTAD--SGP-AGPPPSPPSTSPALDPSQSLLGLEQEAVLPRMGHLRVPMEEDQLSPLVAADSLLEHVKEDFSG---LLPGE--------FISLSPPHEALDYHFGLEEGEGIRDLFD-CDFGDLTPLDF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01094-1", "uniprot_id": "E2F1_HUMAN", "id": "Q01094-1", "name": "Transcription factor E2F1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALAGAPAGGPCAPALEALLGAGALRLLDS--------SQIVIISAAQDASAPPAPTGP-------AAPAAGPCDPDLLLFATPQAPRP----TPSAPRP------ALGRPPVKRRLDLET-DHQYLAES----SGPARGRGRHP------------------GKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHT--TVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQR-LAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSEN-FQISLKSKQGPIDVFLCPEETVGGISPGKTP----------SQEVTSEEENRATD--SATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSG---LLPEE--------FISLSPPHEALDYHFGLEEGEGIRDLFD-CDFGDLTPLDF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLX5-1", "uniprot_id": "A0A8M2BLX5_DANRE", "id": "A0A8M2BLX5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEGFISGQTSEDLLADFESLLNNGSIDLSED--------HQIVIISTPGTATT---------------STATG----DILLFATPHHTSTGTTSLPDHRRP------ILGRPPVKRKLDLDS-DHQYICTSRTASNGPTPPATPAP------------------PRVPKLAVEKSRYDTSLNLTTKRFLDLLAQSPDGVVDLNWASQVLDVQKRRIYDITNVLEGIHLISKKSKNNIQWLGNRI--DGASLARFQELQKEVSELTEAEEKLDELINKCSLQLRLLTEDTHNKK-LGYVRCQDLRNTVDPPDQIIMVIRAPAETAMQVSEPSEG-YQISLKSSKGPIDVFLCPEDSSGVCSPVTDC----------SPAKSSNQSPAKSDPASQEVTSTPTTLPSSSPLPLHTDSESFLDSDPFSG-----ICAMPDFDLSPLDSDFLLERSGAADGLG---LPLDS--------FICLSPPHS-QDYHFGLEDHEGVSELFD-CDFSDLVPLEF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27368-1", "uniprot_id": "E2F1_DROME", "id": "Q27368-1", "name": "Transcription factor E2f1", "aln": "--------------------------------------------------------------------------------------------------------------------------MSKFFVNVAPINNSNSSSSHTTTSSNTQRHQQHQQHYGGSGTTGHTMVARRLNYDLHGGTTSINNNNNIVIKNESVDLDYDHVLSSSDSNSNGGVAAHLRDHVYISLDKGHNTGAVATAAAAATAGHTQQQLQQQHHHQNQQQRKATGKSNDITNYYKVKRRPHAVSDEIHPKKQAKQSAHHQTVYQKHTASSAPQQLRHSHHQLRHDADAELDEDVVERVAKPASHHPFSLSTPQQQLAASVASSSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQS---MVSQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTATSTRLHPLTNQRLNDPLFNNIDAMSTKGLFQTPYRSARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQPEEDDVDVELNQLVPTLTNPVVRTHQFQQHQQPSIQELFSSLTESSPPTPTKRRREAAAAAIAAGSSTTATTTLNSHNNRNHSNHSNHSNHSSSNNSKSQPPTIGYGSSQRRSDVPMYNCAMEGATTTSATADTTAATSRSAAASSLQMQFAAVAESNNGSSSGGGGGGGGYGSIAGAGANADPHQPYSHDRNSLPPGVADCDANSNSSSVTLQGLDALFNDIGSDYFSNDIAFVSINPPDDNDYPYALNANEGIDRLFDFGSDAYGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . . :* : .: * :.** *::*: *: : .*::*** .: * *:***:*******:**.:: **:**:::* : . : : * *. *:. :. .: :::: . :.** :*: :* ::.::** :: : ...* *:*:** ", "identical_positions": 45, "similar_positions": 64, "identity": "4.84%" }, { "cls_id": "homologset.agr.FB:FBgn0011768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28332-1", "uniprot_id": "ADH6_HUMAN", "id": "P28332-1", "name": "Alcohol dehydrogenase 6", "aln": "------------MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTE---MKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFC-IQF----KQSKTQLMSDGTSRFT-CKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQ-DLKK--PIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLP-ASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKW-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XI95-1", "uniprot_id": "ADH6_RAT", "id": "Q5XI95-1", "name": "Alcohol dehydrogenase 6", "aln": "------------MGTQGKVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCGTD---IKHLDTQELSKFCPMIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNIC-TEI----RLSKTHLASEGTSRIT-CKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCGFATGYGAAINSAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATDCVDPR-DFEK--PIEEVLSDMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLSIRSHLFFSGRILKGSILGGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQCIRCVLLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1D5RMB0-1", "uniprot_id": "A0A1D5RMB0_MOUSE", "id": "A0A1D5RMB0-1", "name": "", "aln": "-----MEQASLATKTSSNVIRCRAAVAWTTNAPLSIEEVEVDPPKAGEVRVKIIASGICGTD---NHTLEG-KMKTPFPVILGHEGAGVVESVGPGVTTVKPGDKVLMFPLPECRECFYCLYPKGNFCEKEN----ILSPTGLMLDGTSRFT-CRGKKIYNIMGTSTFTEYTVVHEIAVAKIEAAAPMDTVCIMSCAVPTGFGAVFNTAQVTPGSSCVVFGLGGIGSAIVMACKASGACRIIGVDINEEKFPRARALGVTDCLNPN-KLKK--PVQEVVKEMTGVGVDFAFEAIGLIETMVAALKSCNRSYGVCVIMGVAP-TGSQLSFDPLVLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQKKINIDPLITHRLPFPKINEGFRLLQEGKCIRCVLSMRP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZM50-1", "uniprot_id": "A0A8I5ZM50_RAT", "id": "A0A8I5ZM50-1", "name": "", "aln": "-----MERDSHTTKTSGDVITCRAAVAWTTNAPLSVEEVTVDPPKACEVRVKIISSGICGTD---NHILEG-KMETPFPVILGHEGAGIVESIGQGVTTVKPGDKVLMFPLPECRECIYCLHPKGNFCKKQN----ILSPTGLMLDGTSRFT-CRGKKIYHLQGTSTFTEYTVVDEIAVAKINDRAPMDTVCIISCEVSTGFGAVFNTAQVTPGSTCVVFGLGGIGSAIVMACKASGASRIIRVDTDEQKFPRARALGVTDCLNPK-KLEK--PVQKVVKEMTGVGVDFAFEAIGLIETMVSALKSCNRSSGVCVIMGVAP-TGSQLSFDPVLLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQK-FNIEPLITHRLPFPEINEGFKLLREGKCIRCVLSMRP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5Z6-1", "uniprot_id": "E9Q5Z6_MOUSE", "id": "E9Q5Z6-1", "name": "", "aln": "------------MNTLGKTITCRAAIAWAKNSPLSIEEVQVEPPKSGEVRIKMISSGICGSD---DHVLKG-ELVVNFPLIPGHEGAGIVESVGDGVCSMKPGDKVLILIIPQCRECDACLHPKGNFCYKQD----VLPCSGVMLDGTSRFS-CRGQKIYHSFRTSSFTEYTVVPEIAAVKIDDAAPMDKVCLISCGFPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEEKFPRARALGVTDCLNPN-KLEK--PVQEVVMEMTGVGVDFAFEAIGLVDTMVAAWNSCNNSYGVCLIAGLAP-SDAQLSLEAPKILSGKTLKGVCLGDYKTRDCIPQIVTDYLQNKINIDPLVTYQLPFNQLHEALELFHSGKAIRCVLLF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZT84-1", "uniprot_id": "D3ZT84_RAT", "id": "D3ZT84-1", "name": "", "aln": "------------MDTLGKTITCRAAIAWAENSPLSIEEVQVEPPKSGEVRIKMISSGICGSD---DHMLKG-ELLANFPLIPGHEGAGIVESVGDGVCSVKPGDKVLTLIIPQCRECDSCLHLKGNFCEKQD----VLPCSGVMLDGTSRFS-CRGRKIYHSFRTSSFTEYTVVPEIAVVKIDDAAPMDKVCLISCGFPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEQKFPRARALGVTDCLNPK-KLEK--PVQEVVKEMTGVGVDFAFEAIGQVDTMAAAWNSCNHSYGVCLIVGLAP-SDTHLSLEASKILSGKTLKGVCLGDYKTRDCIPQIVTDYLQNKINIDPLVTHQLPFSQLHKALELYHSGKTIRCVLLF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64437-1", "uniprot_id": "ADH7_MOUSE", "id": "Q64437-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH7", "aln": "------------MGTAGKVIKCKAAVLWGVNQPFSIEEIEVAPPKAKEVRVKILATGICRTD---DHIIKG-SMVSKFPVIVGHEAVGVVESVGEGVTTVRPGDKVIPLFLPQCRECNACLNPEGNLCIRSD-----LTGRGVLADGTTRFT-CKGKPVQHFMNTSTFTEYTVLDESSVAKVDGAAPPEKACLIGCGFSTGYGAAVKTAKVTPGSTCVVFGLGGVGLSVIMGCKAAGASRIIGIDINKDKFQKALAVGATECISPK-DSTK--PISEVLSDMTGNTIQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPP-SAKMLTYDPMLLFTGRTWKGCVFGGWKSRDDVPKLVTEFLEKKFDLDQLITHTLPFNNINEGFELLYSGKSIRTVLTF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41682-1", "uniprot_id": "ADH7_RAT", "id": "P41682-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH7", "aln": "------------MDTAGKVIKCKAAVLWGTNQPFSIEDIEVAPPKAKEVRVKILATGICGTD---DHVIKG-TMVSKFPVIVGHEAVGIVESVGEEVTTVRPGDKVIPLFLPQCRECNPCRNPEGNLCIRSD-----LTGRGVLADGTTRFT-CKGKPVQHFMNTSTFTEYTVLDESSVAKIDAEAPPEKACLIGCGFSTGYGAAVKTAKVSPGSTCAVFGLGGVGLSVVMGCKAAGASRIIGIDINKDKFQKALDVGATECINPR-DFTK--PISEVLSDMTGNTVQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPP-SAKMLSYDPMLLFTGRTWKGCVFGGWKSRDDVPKLVTEFLEKKFDLGQLITHTLPFHNISEGFELLYSGQSIRTVLTF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40394-1", "uniprot_id": "ADH7_HUMAN", "id": "P40394-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH7", "aln": "MFAEIQIQDKDRMGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTD---DHVIKG-TMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSD-----ITGRGVLADGTTRFT-CKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK-DSTK--PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP-SAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00329-1", "uniprot_id": "ADH1_MOUSE", "id": "P00329-1", "name": "Alcohol dehydrogenase 1", "aln": "------------MSTAGKVIKCKAAVLWELHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSD---DHVVSG-TLVTPLPAVLGHEGAGIVESVGEGVTCVKPGDKVIPLFSPQCGECRICKHPESNFCSRSD----LLMPRGTLREGTSRFS-CKGKQIHNFISTSTFSQYTVVDDIAVAKIDGASPLDKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYSK--PIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHAACGVSVVVGVPP-NAQNLSMNPMLLLLGRTWKGAIFGGFKSKDSVPKLVADFMAKKFPLDPLITHVLPFEKINEAFDLLRSGKSIRTVLTF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06757-1", "uniprot_id": "ADH1_RAT", "id": "P06757-1", "name": "Alcohol dehydrogenase 1", "aln": "------------MSTAGKVIKCKAAVLWEPHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSD---DHAVSG-SLFTPLPAVLGHEGAGIVESIGEGVTCVKPGDKVIPLFSPQCGKCRICKHPESNLCCQTKN---LTQPKGALLDGTSRFS-CRGKPIHHFISTSTFSQYTVVDDIAVAKIDAAAPLDKVCLIGCGFSTGYGSAVQVAKVTPGSTCAVFGLGGVGLSVVIGCKTAGAAKIIAVDINKDKFAKAKELGATDCINPQ-DYTK--PIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHSACGVSVIVGVPP-SAQSLSVNPMSLLLGRTWKGAIFGGFKSKDAVPKLVADFMAKKFPLEPLITHVLPFEKINEAFDLLRAGKSIRTVLTF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00325-1", "uniprot_id": "ADH1B_HUMAN", "id": "P00325-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH1B", "aln": "------------MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTD---DHVVSG-NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKND----LGNPRGTLQDGTRRFT-CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYKK--PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP-ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00326-1", "uniprot_id": "ADH1G_HUMAN", "id": "P00326-1", "name": "Alcohol dehydrogenase 1C", "aln": "------------MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSD---EHVVSG-NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKND----LGNPRGTLQDGTRRFT-CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYKK--PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP-DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07327-1", "uniprot_id": "ADH1A_HUMAN", "id": "P07327-1", "name": "Alcohol dehydrogenase 1A", "aln": "------------MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTD---DHVVSG-TMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKND----VSNPQGTLQDGTSRFT-CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ-DYKK--PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP-DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28474-1", "uniprot_id": "ADHX_MOUSE", "id": "P28474-1", "name": "Alcohol dehydrogenase class-3", "aln": "--------------MANQVIRCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKILATAVCHTD---AYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIR----VTQGKGLMPDGTSRFT-CKGKSVFHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGAAVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGASECISPQ-DFSK--SIQEVLVEMTDGGVDYSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEE-ISTRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTGNLSFDQINQAFDLMHSGDSIRTVLKM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12711-1", "uniprot_id": "ADHX_RAT", "id": "P12711-1", "name": "Alcohol dehydrogenase class-3", "aln": "--------------MANQVIRCKAAVAWEAGKPLSIEEIEVAPPQAHEVRIKIIATAVCHTD---AYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIR----VTQGKGLMPDGTSRFT-CKGKPILHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGAAVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGATECINPQ-DFSK--SIQEVLIEMTDGGVDFSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEE-ISTRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTGNLSFDQINKAFDLMHSGNSIRTVLKM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11766-1", "uniprot_id": "ADHX_HUMAN", "id": "P11766-1", "name": "Alcohol dehydrogenase class-3", "aln": "--------------MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTD---AYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIR----VTQGKGLMPDGTSRFT-CKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQ-DFSK--PIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEE-IATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32771-1", "uniprot_id": "FADH_YEAST", "id": "P32771-1", "name": "S-(hydroxymethyl)glutathione dehydrogenase", "aln": "----------MSAATVGKPIKCIAAVAYDAKKPLSVEEITVDAPKAHEVRIKIEYTAVCHTD---AYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAECGKCKFCTSGKTNLCGAVR----ATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDCTGNTKIMRDALEACHKGWGQSIIIGVAAAGEE-ISTRPFQLVTGRVWKGSAFGGIKGRSEMGGLIKDYQKGALKVEEFITHRRPFKEINQAFEDLHNGDCLRTVLKSDEIK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P46415-1", "uniprot_id": "ADHX_DROME", "id": "P46415-1", "name": "Alcohol dehydrogenase class-3", "aln": "-----------MSATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTD---AFTLSGADPEGLFPVVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIR----LTQGAGVMPEGTSRLS-CKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPK-DVADKGSIQNYLIDLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQE-ISTRPFQLVVGRVWKGSAFGGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QAY7-1", "uniprot_id": "A0A8M9QAY7_DANRE", "id": "A0A8M9QAY7-1", "name": "Alcohol dehydrogenase 6", "aln": "---------MVAMETEGKVIKCKAAVAWEPGKPLSIEKVEVAPPKAHEVRIKIAASGVCHSDWAYLYDIAKMKPR-PFPLVLGHEGAGVVESVGPGVTKVSIGDKVIPLFLPQCGQCERCQSPKTNLCTKNW----EKTQQGVLADGTSRIT-CKNQQVHQFIGISTFSEYTVVPEDNVTKIHPDAPLDRVCLLGCGVSTGYGAAVNTGKVESGSTCAVFGLGAVGLAAVMGCKAAGASRIIAVDINSDKFEIGKTFGATEFVNPK-DHSK--SIQEVLRELTNGGVDYALECVGDVAVMRAAVEACSPAGGVCVIVGWIEV-EE-LSLAPLDILLGRTLKGTYFGGWKSVEAVPRLVQDYLSRKILLDEFVTHRLALDQINQAFDLIMSGKSIRTVIEM----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QYY9-1", "uniprot_id": "ADH4_MOUSE", "id": "Q9QYY9-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH4", "aln": "------------MGTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTD---INATDPKKK-ALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFT-CKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGAAINTAKVTPSSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATDCLNPR-ELDK--PVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVDK---MTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDAIDLMKEGKSIRTILTF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64563-1", "uniprot_id": "ADH4_RAT", "id": "Q64563-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH4", "aln": "------------MGTQGKVITCKAAIAWKTDSPLCIEEIEVSPPKAHEVRIKVIATCVCPTD---INATNPKKK-ALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKKCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFT-SKERSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFTSGYGAAINTAKVTPGSACAVFGLGCVGLSAVIGCKIAGASRIIAIDINSEKFPKAKALGATDCLNPR-DLDK--PVQDVITELTGGGVDFSLDCAGTAQTLKAAVDCTVVGWGSCTVVGAKVDE---MNISTVDMILGRSVKGTFFGGWKSVDSVPNLVTDYKNKKFDLDLLVTHALPFDKINDAIDLMNQGKSIRTILTF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08319-1", "uniprot_id": "ADH4_HUMAN", "id": "P08319-1", "name": "All-trans-retinol dehydrogenase [NAD(+)] ADH4", "aln": "------------MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTD---ATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFT-CKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR-DLHK--PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG-LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * * *:: : *: :*.: * .*:: ***::: :* :: * : *** .*:***:* * . ** *: : . * .* * * * : * *: . . : : .:* :***: : . :. : : .*::.* ..:*:*:..: .:: .. .*:* * :* : ..* ** :* :* : .: .* :: :.*. . . .: . : :: . : :: * : : . * . * : .. *: :. *. : . : :: :: : : ::* : . ... *. ", "identical_positions": 57, "similar_positions": 117, "identity": "14.11%" }, { "cls_id": "homologset.agr.FB:FBgn0011769", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPW2-1", "uniprot_id": "FDX2_MOUSE", "id": "Q9CPW2-1", "name": "Ferredoxin-2, mitochondrial", "aln": "-MAASMARG-VSARVLLRAAGGSWGPRAG--------HAAVTSRT-FGTTGERR------AGEEAADSPE----LPRDVVNVVFVDRSGKRIPVRGKVGDNVLYLAQRHGVDLEGACEASLACSTCHVYVSEAHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGVEFALPKITRNFYVDGHIPKPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8N2-1", "uniprot_id": "D4A8N2_RAT", "id": "D4A8N2-1", "name": "Ferredoxin-2, mitochondrial", "aln": "-MAASMARG-VSARVLLRAAGGSWGPRAG--------HAAVTSRT-FGSTGERR------AGEDEADSPE----LPRDVVNVVFVDRSGKRIPVRGRVGDNVLHLAQRHGVDLEGACEASLACSTCHVYVSEAHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGAEFALPKITRNFYVDGHIPKPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4F2-1", "uniprot_id": "FDX2_HUMAN", "id": "Q6P4F2-1", "name": "Ferredoxin-2, mitochondrial", "aln": "-MAASMARGGVSARVLLQAARGTWWNRPGGTSGSGEGVALGTTRK-FQATGSRP------AGEEDAGGPE----RPGDVVNVVFVDRSGQRIPVSGRVGDNVLHLAQRHGVDLEGACEASLACSTCHVYVSEDHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGAEFTLPKITRNFYVDGHVPKPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C57-1", "uniprot_id": "FDX2_DANRE", "id": "Q08C57-1", "name": "Ferredoxin-2, mitochondrial", "aln": "MAAAAAVRAGVNFTQRLNRISPVCRVCPLLRLNRCTGAAVRRAVDGFSAPSRRLRTSIGVCQSEDSSAPEEDAHAQEHIVNVVYIDRSGRRIPVQARVGDNVLYLAHKHGIDLEGACEASLACSTCHVYVSSGHYDRLPEPEEREDDMLDMAPLLQENSRLGCQIILTPELDGMELTLPKVTRNFYVDGHVPKPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P37193-1", "uniprot_id": "ADXH1_DROME", "id": "P37193-1", "name": "Adrenodoxin-like protein 1, mitochondrial", "aln": "MFCLLLRRSAVHNSCKLISKQIAKP-------------AFYTPHNALHTTIPRR------HGEFEWQDPK----STDEIVNITYVDKDGKRTKVQGKVGDNVLYLAHRHGIEMEGACEASLACTTCHVYVQHDYLQKLKEAEEQEDDLLDMAPFLRENSRLGCQILLDKSMEGMELELPKATRNFYVDGHKPKPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12184-1", "uniprot_id": "ADRX_YEAST", "id": "Q12184-1", "name": "Adrenodoxin homolog, mitochondrial", "aln": "-MLKIVTRAGHTARISNIAAHLLRTSPSL--------LTRTTTTTRFLPFSTSS-----FLNHGHLKKPK-----PGEELKITFILKDGSQKTYEVCEGETILDIAQGHNLDMEGACGGSCACSTCHVIVDPDYYDALPEPEDDENDMLDLAYGLTETSRLGCQIKMSKDIDGIRVALPQMTRNVNNNDFS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : . : . *: . :::.:: :.* : *:.:* :*: *.:::**** .* **:**** *. : : * .*: *:*:**:* * *.******* : .::* .. **: ***. :.. ", "identical_positions": 41, "similar_positions": 47, "identity": "21.03%" }, { "cls_id": "homologset.agr.FB:FBgn0011770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZJ4-1", "uniprot_id": "F1LZJ4_RAT", "id": "F1LZJ4-1", "name": "Putative hydroxypyruvate isomerase", "aln": "MAPLRFSANVSWLFPELP-GVPERLHAAGRAGFEAAEVAWPYAESPQALASAARAAGLRLVLINTPRGDHE-KGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPRGADREAVKGEMETVFVENLRHAAEVLAQENLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQVMDGNLTGNIREFLPIVGHVQVAQVPDRGEPGSSGELDFTYLFQLLEDEGYQGFVGCEYRPRGDTVEGLSWLRSYWDRWGHPRTGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1F5-1", "uniprot_id": "HYI_MOUSE", "id": "Q8R1F5-1", "name": "Putative hydroxypyruvate isomerase", "aln": "MAPLRFSANVSWLFPELP-GLPERLHAAGRAGFKAAEVAWPYTESPQALASAAQTAGLRLVLINTPRGDHE-KGEMGLGAVPGRQAAFREGLEQAVLYAKALGCPRIHLMAGRVPQGADRAAVKGEMETVFVENLKHAAGVLAQENLVGLLEPINTRITDPQYFLDTPRQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPTVGHVQVAQVPDRGEPGSSGELDFTYLFQLLEDEGYQGFVGCEYRPRGDTVEGLSWLRSYWDRRGHPRTGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T013-1", "uniprot_id": "HYI_HUMAN", "id": "Q5T013-1", "name": "Putative hydroxypyruvate isomerase", "aln": "MAPLRFSANLSWLFPELS-GLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLINTPPGDQE-KGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVGCEYQPRGDTVEGLSWLRSYWDRRGHPEAGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3H9-1", "uniprot_id": "HYI_DANRE", "id": "Q7T3H9-1", "name": "Putative hydroxypyruvate isomerase", "aln": "MAPLKFCANISWLFTELP-EFPQRMRAAASAGFRAVEAAWLYNTDLKELKTAKEETGLEFVLINTPPGDAS-AGDLGLAAVPGREQEFRQGLDLAVQYAKALDCTRIHLMAGRVPAGSERCALALQMEDTFVHNLKHAAGVLDKEGLLGLIEPINSRITDPRYFLHSPHQAAEILQRVDHPSIKMQMDIFHWQIMDGNLTHNIRRYLPMTGHIQIAQVPDRHEPDSPGELNFSFIFRLLEELDYQGFIGCEYKPQGSTEAGLEWLRKYWRSRNGGERD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36951-1", "uniprot_id": "HYI_DROME", "id": "P36951-1", "name": "Putative hydroxypyruvate isomerase", "aln": "-MALKFAANLNFLFTERATSIAERIRLAHQNGFRAVEIPYPEGETS-DVVSAVKETGVVVSLVNLAFDKSDDQLRFGSTSVPGSEKLFRSQLDATIDFARQVNCGKIHLTAGLFKGGQE-----SDYTKTYTANLKIAADSLRASKMIGVIEPIN-KYAVPGYYMNSYSKAAGILADVAADNIQLLADLYHLQHLHGNVSKTLEEYKALIGHFQIAQVPHRHEPDVSGELDYGFVFKALQEFGYDGWIGCEYKPKTTTVEGLGWVSKLGYTL-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:*.**:.:**.* . .. *:: * **.*.* .: : * . :*: . *:* . .. . :* :*** : **. *: :: :*: :.* :*** ** . * : : .: **: ** * . ::*::**** : : * *::.: :** ** * .::: *::* * :.**:: .:..: . **.*:**** * **. .***:: ::*: *:: .*.*::****:*: * ** *: . ", "identical_positions": 80, "similar_positions": 91, "identity": "28.67%" }, { "cls_id": "homologset.agr.FB:FBgn0011771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55161-1", "uniprot_id": "NCKP1_RAT", "id": "P55161-1", "name": "Nck-associated protein 1", "aln": "MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCDLLNTIDVCQVFFDITVNFDLTKNYLDLTVTYTTLMILLSRIEERKAIIGLYNYAHEMTHGASDREYPRLGQMIVDYEHPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDAMEKWIIFGFILCHGMLNTEATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPK---KSADDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLSLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKK--SKKQTGKKGEPEREKPGVESMRKNRLVVTNLDKLHTALSELCFSINYVPNMAVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSELLTSVREYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDM--------------------------------------IVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28660-1", "uniprot_id": "NCKP1_MOUSE", "id": "P28660-1", "name": "Nck-associated protein 1", "aln": "MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCDLLNTIDVCQVFFDITVNFDLTKNYLDLTVTYTTLMILLSRIEERKAIIGLYNYAHEMTHGASDREYPRLGQMIVDYENPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDAMEKWIIFGFILCHGMLNTEATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPK---KSADDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLSLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKK--SKKQTGKKGEPEREKPGVESMRKNRLVVTNLDKLHTALSELCFSINYVPNMAVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDM--------------------------------------IVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2A7-1", "uniprot_id": "NCKP1_HUMAN", "id": "Q9Y2A7-1", "name": "Nck-associated protein 1", "aln": "MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDVCQVFFDITVNFDLTKNYLDLIITYTTLMILLSRIEERKAIIGLYNYAHEMTHGASDREYPRLGQMIVDYENPLKKMMEEFVPHSKSLSDALISLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDAMEKWIIFGFILCHGILNTDATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNIRGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPK---KSADDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKK--SKKQTGKKGEPEREKPGVESMRKNRLVVTNLDKLHTALSELCFSINYVPNMVVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDM--------------------------------------IVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6R1-1", "uniprot_id": "NCKP1_DANRE", "id": "B0S6R1-1", "name": "Nck-associated protein 1", "aln": "MSRGAMQPSQQKLAEKLTILNDRGIGMLTRIYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDACQVFFDITVNFDLTKNYLDLVVTYTTLMLLLSRIEERKAIIGLYNYAHEMTHGSSDREYPRLGQMIVDYENPLKKMMEEFVPHGKSLSDALVSLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDTMEKWIVFGFILCHAALNSDPAALSLWKLALQSSTCLCLFRDEVFHIHKAAEDLFVNIRGYNKRVNDIRECKESALSHAGSMHRERRKFLRSALKELATVLADQPGLLGPKALFVFMALSFARDEIIWLLRHADN--IQK---KSTDDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSISFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKK--SKKQTGKKGEPEREKPGVESMRKNRLLVTNLDKLHTALSELCFSINYVPNMMVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQTTQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVDNVEVLTQMRTSFDKPDHMAALFKRLTSVDSVLKRMTIIGVILSFRSLAQEALRDVLSCHIPFLVSSVEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSMPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGS-IEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDM--------------------------------------IVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVSSSA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P55162-1", "uniprot_id": "HEM_DROME", "id": "P55162-1", "name": "Membrane-associated protein Hem", "aln": "MAR-PIFPNQQKIAEKLIILNDRGLGILTRIYNIKKACGDTKSKPGFLSEKSLESSIKFIVKRFPNIDVKG----LNAIVNIKAEIIKSLSLYYHTFVDLLDFKDNVCELLTTMDACQIHLDITLNFELTKYYLDLVVTYVSLMIVLSRVEDRKAVLGLYNAAYELQNNQADTGFPRLGQMILDYEVPLKKLAEEFIPHQRLLTSALRSLTSIYALRNLPADKWREMQKLSLVGNPAILLKAVRTDTMSCEYISLEAMDRWIIFGLLLNHQMLGQYPEVNKIWLSALESSWVVALFRDEVLQIHQYIQATFDGIKGYSKRIGEVKEAYNTAVQKAALMHRERRKFLRTALKELALIMTDQPGLLGPKAIFIFIGLCLARDEILWLLRHNDNPPLLKNKGKSNEDLVDRQLPELLFHMEELRALVRKYSQVMQRYYVQYLSGFDATDLNIRMQSLQMCPEDESIIFSSLYNTAAALTVKQVEDNELFYFRPFRLDWFRLQTYMSVGKAALRIAEHAELARLLDSMVFHTRVVDNLDEILVETSDLSIFCFYNKMFDDQFHMCLEFPAQNRYIIAFPLICSHFQNCTHEMCPEERHHIRERSLSVVNIFLEEMAKEAKNIITTICDEQCTMADALLPKHCAKILSVQSARK--KKDKSKSKHFDDIRKPGDESYRKTREDLTTMDKLHMALTELCFAINYCPTVNVWEFAFAPREYLCQNLEHRFSRDLVGMVMFNQETMEIAKPSELLASVRAYMNVLQTVENYVHIDITRVFNNCLLQQTQALDSHGEKTIAALYNTWYSEVLLRRVSAGNIVFSINQKAFVPISPEGWVPFNPQEFSDLNELRALAELVGPYGIKTLNETLMWHIANQVQELKSLVSTNKEVLITLRTSFDKPEVMKEQFKRLQDVDRVLQRMTIIGVIICFRNLVHEALVDVLDKRIPFLLSSVKDFQEHLPGGDQIRVAS---EMASAAGLLCKVDPTLATTLKSKKPE--FDEGEHLTACLLMVFVAVSIPKLARNENSFYRATIDGHSNNTHCMAAAINNIFGALFTICGQSDMEDRMKEFLALASSSLLRLGQESDKEATRNRESIYLLLDE--------------------------------------IVKQSPFLTMDLLESCFPYVLIRNAYHGVYKQEQILGLAL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0L3V1-1", "uniprot_id": "A0ABK0L3V1_RAT", "id": "A0ABK0L3V1-1", "name": "", "aln": "--MSLTSAYQHKLAEKLTILNDRGQGVLIRMYNIKKTCSDPKSKPPFLLEKSMESCLKYINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQCHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRLLIGMYNCAHEMLHGHGDPSFPRLGQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLYFLFVRRNQGAEQWRSAQLLSLISSPPAMINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLEGSLYITLIREDVLQVHKVTEDLFSSLKGYSKRVADIKESKEHAITNSGQFHCQRRQFLRTAVKELETVLNDEPGLLGPKALFAFMALSFIRDEVTWLVRHTEN--VTKT--KTPEDYADSSIAELLFLLEEIRALVRRHIKVIQQYHLQYLARFDVLVLSDIIQNLTVCPEEESVIMSSFVSTLSSLNLKQVDNEEKFDFSGLRLDWFRLQAYTSVAKAPLHLHENPDLAKVMNLIIFHSQMLDSVEKMLVETSDLSTFCFHLRTFEKMFATTLEEPTMLRYTIAFPLICAHFVHCIHEMCPEEYPHLKNHGLHHCNSFLEELAKQTSNCVLEICAEQRNLNEQLLPKHCATTISKAKNRKSMKQRQAPRKGEPERDKPGAESHRKNRSLVTNMDKLHLNLTELALAMNHVHSFSVFEHTIFPSEYLSSHLESRLNRAIVSLAGYNATTQEILRPSELLAGVKAYTSFIQSLAQFLGTDASRIVRNALLQQTQPLDSCGEQTVTTLYTNWYLESLLRQASSGTIVLSPAMQAFISLPRDGEQNFSAEEFSDISEMRALAEILGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFTKPELMASLLPQLTGAENVLKRMTIIGVILSFRAMAQEGLQEVFSAHCPFLMGPIECLKEFVTPDTDIKVTLSVFELACAAGVSCDIDPALVAAIANLKADNSSPEEEYKVACLLLIFLAVSLPLLATDPSSFFSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKN-IETHLKEFLVVASVSLLQLGQETDKLKTRNRESISLLMRLPHLLCHDLHIQACPKRWGGSCPWQPWQEQSQDQAHFAEVVEESPFLTLDMLESCFPYVLLRNAYREVSRAFYLNRLPASSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1X4-1", "uniprot_id": "NCKPL_MOUSE", "id": "Q8K1X4-1", "name": "Nck-associated protein 1-like", "aln": "--MSLTSAYQLKLAEKLTILNDRGQGVLIRMYNIKKTCSDSKSKPPFLLEKSMESCLKYINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQCHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRILIGMYNCAHEMLHGHSDPSFARLGQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLHFLFVRRNQGAEQWRSAQLLSLISSPPAMINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLEGSLYITLIREDVLQVHKVTEDLFSSLKGYSKRVADIKESKEHAITNSGQFHCQRRQFLRTAVKELETVLNDEPGLLGPKALFAFMALSFIRDEVTWLVRHTEN--VTKT--KTPEDYADSSIAELLFLLEEIRALVRRHIKVIQQYHLQYLARFDVLVLSDIIQNLSVCPEEESVIMSSFVSILSSLNLKQVDNEEKFDFSGLRLDWFRLQAYTSVSKAPLHLHENPDLAKVMNLIIFHSQMLDSVEKMLVETSDLSTFCFHLRTFEKMFATTLEEPTMLRYTIAFPLICAHFVHCVHEMCPEEYPHLKNHGLHHCNSFLEDLAKQTSNCVLEICAEQRNLNEQLLPKHCATTISKAKNKKSMKQRQAPRKGEPERDKPGAESHRKNRSLVTNMDKLHLNLTELALAMNHVHSFSVFEHTIFPSEYLSSHLEARLNRAIVTLAGYNATTQEILRPSELLAGVKAYISFIQSLAQFLGADASRIVRNALLQQTQPLDSSGEQTVTTLYTNWYLESLLRQASSGAIVLSPAMQAFISLPRDGEQNFSAEEFSDISEMRALAEILGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFSKPELMASLLPQLTGAENVLKRMTIIGVILSFRAMAQEGLQEVFSAHCPFLMGPIECLKEFVTPDTDIKVTLSVFELACAAGVSCDIDPALVAAIANLKADNSSPEEEYKVACLLLIFLAVSLPLLATDPSSFFSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKN-IETHLKEFLVVASVSLLQLGQETDKLKTRNRESISLLMRL--------------------------------------VVEESPFLTLDMLESCFPYVLLRNAYREVSRAFYLNRLPASSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55160-1", "uniprot_id": "NCKPL_HUMAN", "id": "P55160-1", "name": "Nck-associated protein 1-like", "aln": "--MSLTSAYQHKLAEKLTILNDRGQGVLIRMYNIKKTCSDPKSKPPFLLEKSMEPSLKYINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQCHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRILIGMYNCAHEMLHGHGDPSFARLGQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLHFLFVRRNQGAEQWRSAQLLSLISNPPAMINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLQGSLYITLIREDVLQVHKVTEDLFSSLKGYGKRVADIKESKEHVIANSGQFHCQRRQFLRMAVKELETVLADEPGLLGPKALFAFMALSFIRDEVTWLVRHTEN--VTKT--KTPEDYADSSIAELLFLLEGIRSLVRRHIKVIQQYHLQYLARFDALVLSDIIQNLSVCPEEESIIMSSFVSILSSLNLKQVDNGEKFEFSGLRLDWFRLQAYTSVAKAPLHLHENPDLAKVMNLIVFHSRMLDSVEKLLVETSDLSTFCFHLRIFEKMFAMTLEESAMLRYAIAFPLICAHFVHCTHEMCPEEYPHLKNHGLHHCNSFLEELAKQTSNCVLEICAEQRNLSEQLLPKHCATTISKAKNKKTRKQRQTPRKGEPERDKPGAESHRKNRSIVTNMDKLHLNLTELALTMNHVYSFSVFEHTIFPSEYLSSHLEARLNRAIVWLAGYNATTQEIVRPSELLAGVKAYIGFIQSLAQFLGADASRVIRNALLQQTQPLDSCGEQTITTLYTNWYLESLLRQASSGTIILSPAMQAFVSLPREGEQNFSAEEFSDISEMRALAELLGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFSKPDLMASLLPQLTGAENVLKRMTIIGVILSFRAMAQEGLREVFSSHCPFLMGPIECLKEFVTPDTDIKVTLSIFELASAAGVGCDIDPALVAAIANLKADTSSPEEEYKVACLLLIFLAVSLPLLATDPSSFYSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKN-IETHLKEFLVVASVSLLQLGQETDKLKTRNRESISLLMRL--------------------------------------VVEESSFLTLDMLESCFPYVLLRNAYREVSRAFHLN-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *:**** ****** *:* *:*****:*.*.*:** :* :*.:*..:*:* ::** ::.:. * : . *:**:: *: ** :***:::*:*:* :**.*:*.** .:**.:**::*: **** :**.:::::***:*:*: ::*:** *:*: :. .* :.*****:::*: ****: *** ** : ::.** ** :: ** *::**. * ***:. *. :::...:***.***:*::.*::**::*::* * *. . .:* .*:.* : *:*::*:::*: : * .::**.**: :::*. : .: ::. :* :**:*** *:*** :: *:********:* *:.*.: ***: **:** :* : * *: :* * :.**:* :* :*: **:: *:*:*::***: **. *. :*.* :***:**:*:**: . ::*.:***:: * * * :********:* **.**.* : :: :*.:::: ::**::::*.: ::******** ***: : *:. * ** .: ** *:***:*:** * **:**** *: ::.* * **:::**:: * : ** ** .: : *******. :* :* .: :: * : *** ** **.* :*.:**** *:**.:::*: .. *:*.:: * *** .:** *:.: :* :. :* * ** :*****:.*: * .:*:: ::: * :*:..* ****** *** ** *:::**..** * ***:.* * * :**: :. :. *..:*:**:.*:*:*:*::****:* *.*.****::.*: ***.** * ::* :*:.* **: * : :* ..: **:********:.** :.:*.* :*:. : ***:..:: :::.:. :::*: *::.***: *.:**:*..:: . *.: * *: ****::*:***:* ** : * : :*: ** **:: ** :: .****: . :* ::****.:** ***::***:** ******: **: :*::*.***:*:*********:****: * : ", "identical_positions": 463, "similar_positions": 391, "identity": "39.27%" }, { "cls_id": "homologset.agr.FB:FBgn0011774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT85-1", "uniprot_id": "E9PT85_RAT", "id": "E9PT85-1", "name": "DNA repair protein Ku70", "aln": "MSEWESYYKTEGEE--EEEEEQSPDTNGEYKYSGRDSLIFLVDASRAMFESQGEDELT-PFDMSIQCIQSVYTSKIISSDRDLLAVVFYGTEKDKNSVN---------FKSIYVLQDLDNPGAKRVLELDRFKGQQGKKHFRDT----IGHGSDYSLSEVLWVCANLFSDVQ---FKMSHKRIMLFTNEDDP-HGNDSAKASRARTKASDLRDTGIFLDLMHLKKRGGFDVSLFYRDIISI---AEDE-DLGVHFE---ESSKLEDLLR-KVRAKETKKRVLSRLKFKLGKDVALMVGVYNLVQKANKPFPVRLYRE-TNEPVKTK---TRTFNVNTGSLLLPSDTKRSLT-------FGTRQIVLEKEE---TEELKRFDEPGLILMGFKP-MVMLKNHHYLRPSLFLYPEESLVNGSSTLFSALLTKCVEKEVIAVCRYTARKNVSPYFVALVPQEE----ELDDQNIQVTPAGFQLVFLPYADDKRKVPFTEK----VMANPEQIDKMKAIVQ------KLRFTYRSDSFENPVLQQHFRNLEALALDMMESEQVVDLTLPKVEAIKKRLGSLADEFKELVYPPGYNPEGK-IAKRKADNEG--SASKKPKVELSEEELKDLFAKG-TLGKLTVPALRDICK-AYGLKS-GPKKQELLEALSRHLEKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23475-1", "uniprot_id": "XRCC6_MOUSE", "id": "P23475-1", "name": "DNA repair protein Ku70", "aln": "MSEWESYYKTEGEE--EEEEEESPDTGGEYKYSGRDSLIFLVDASRAMFESQGEDELT-PFDMSIQCIQSVYTSKIISSDRDLLAVVFYGTEKDKNSVN---------FKNIYVLQDLDNPGAKRVLELDQFKGQQGKKHFRDT----VGHGSDYSLSEVLWVCANLFSDVQ---LKMSHKRIMLFTNEDDP-HGRDSAKASRARTKASDLRDTGIFLDLMHLKKPGGFDVSVFYRDIITT---AEDE-DLGVHFE---ESSKLEDLLR-KVRAKETKKRVLSRLKFKLGEDVVLMVGIYNLVQKANKPFPVRLYRE-TNEPVKTK---TRTFNVNTGSLLLPSDTKRSLT-------YGTRQIVLEKEE---TEELKRFDEPGLILMGFKP-TVMLKKQHYLRPSLFVYPEESLVSGSSTLFSALLTKCVEKKVIAVCRYTPRKNVSPYFVALVPQEE----ELDDQNIQVTPGGFQLVFLPYADDKRKVPFTEK----VTANQEQIDKMKAIVQ------KLRFTYRSDSFENPVLQQHFRNLEALALDMMESEQVVDLTLPKVEAIKKRLGSLADEFKELVYPPGYNPEGK-VAKRKQDDEG--STSKKPKVELSEEELKAHFRKG-TLGKLTVPTLKDICK-AHGLKS-GPKKQELLDALIRHLEKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12956-1", "uniprot_id": "XRCC6_HUMAN", "id": "P12956-1", "name": "DNA repair protein Ku70", "aln": "MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELT-PFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVN---------FKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDM----MGHGSDYSLSEVLWVCANLFSDVQ---FKMSHKRIMLFTNEDNP-HGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISI---AEDE-DLRVHFE---ESSKLEDLLR-KVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRE-TNEPVKTK---TRTFNTSTGGLLLPSDTKRSQI-------YGSRQIILEKEE---TEELKRFDDPGLMLMGFKP-LVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEE----ELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEK----IMATPEQVGKMKAIVE------KLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGK-VTKRKHDNEG--SGSKRPKVEYSEEELKTHISKG-TLGKFTVPMLKEACR-AYGLKS-GLKKQELLEALTKHFQD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZ60-1", "uniprot_id": "F1QZ60_DANRE", "id": "F1QZ60-1", "name": "", "aln": "MANWGNYFPNEDDVD-EQDEEES---GGDYKSSGRDSLVFLVDASKEMFIKGENGEPS-NFDMTMQCVRSVYTSKIISSDRDLVALVFYGTEQSKNPRNS--------FKHVYVYHDLESPGAKRVQDIDKLKGDKGGQFAEKT----MGSG-ETSLGEALWCCSNLYSDIK---LRLSHKRLMIFTCRDEP-HGGDSAKDRQARTKAADLKETGVAIDLMHLSKPGGFDVSLFFCDIVSP---PEDESDLGLQIE---PCRKLEDLQK-RVRAKELKKRAQCRLTFSLGEGVDLAVGVYVLARTAMKPSAVKLYRD-NNEPVRTK---SRLFHTQTGGILLPNDTKRAQV-------YGQKQIVMEKDE---VDEIKKFDDPGLVLIGFKP-IDRLKLHHHLRPALFIYPEEEQISGSSCMFTALLLKCCEKNVFALCKYIPRRNTPPRFVALVPQRE----ELDQSQTQATPPGFHVIYLPFADDIRTVDPHVG----PTASDEQVDKMKEIVH------KLRFKYRSDAFENPVLQQHYSNLEALALDMLSPEPIEDLTMPKVKMMDDRLGPLVQEFKDLVYPPDYNPEGKPAAKRKPAESGGGAAEKKAKVEISEEELKIHVAKG-TLGKLTVPVLKDACK-QFNIRTTGTKKQELIDALTMQLSK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23976-1", "uniprot_id": "KU70_DROME", "id": "Q23976-1", "name": "ATP-dependent DNA helicase 2 subunit 1", "aln": "MSTWN----PENDVDLLSGSEDEEDVSMKRDYHGREAILFVVDAN------LQTAGVE-RLLEALNIIRTAFISGLLVNDKDLIGLIFANTKHSPPPLEASALDNIVMPDNCAVFLPLRQLTKPIVEHYLEFMGGVETQFADVYGL--AEPDGRGRFDLMIRLCIEMLEKCG---KKLNNAKIAYVTDVREP-HPSNSNHFQAALQKASDLEGK--EFEFHVIPMVDDFDYEPFYKEFITL---SRAIELDAFQVP---DAQMLREILSDRKLKQDFLRRCLGHFSFYLGPNLSMSVQYYNYFQRRAYPRKVQILRR-DNSVVRTKRVITVQKQKDDGSQDIEHEYQIKVTGGWYTCNVGERDLRISMDQ---LNRVRNLHKPQMMLLGFKH-RSSLPEVSYIKPANFMYPDDQSIIGSKRLFRALWERCLVRDKIAICLFMCKRKSIPRYVALVPVEAPDNGEDKNYRSLLCGDGFKIVYLPEAKHIRHLDLQDWNNTENTADEQKVEFFQKIIK------KLRVDYQPNLINDPSLDALQANLLALSLDFSTDTKGLDN-LLDTSQQDKRIEKLLPDY--EMFAPEAEPHKKRAAKSTTAGASGPKMAKIDDDQLKEFEFVKSLNKDEALTSCTAAQLHFILQHHFDVTMPKSSKKAKLVAKIEELHK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32807-1", "uniprot_id": "KU70_YEAST", "id": "P32807-1", "name": "ATP-dependent DNA helicase II subunit 1", "aln": "MRSVTNAFGNSGELN------DQVDETGYRKFDIHEGILFCIELSETMFKESSDLEYKSPLLEILESLDELMSQLVITRPGTAIGCYFYYCNREDAKEG---------IYELFPLRDINATFMKKLNDLLEDLSSGRISLYDYFMFQQTGSEKQVRLSVLFTFMLDTFLEEIPGQKQLSNKRVFLFTDIDKPQEAQDIDERARLRRLTIDLFDNKVNFATFFIGYADKPFDNEFYSDILQLGSHTNENTGLDSEFDGPSTKPIDAKYIKSRILRKKEVKRIMFQCPLILDEKTNFIVGVKGYTMYTHEKAGVRYKLVYEHEDIRQEAYSKRKFLNPITGEDVTGKTVKVYP-------YGDLDINLSDSQDQIVMEAYTQKDAFLKIIGFRSSSKSIHYFNNIDKSSFIVPDEAKYEGSIRTLASLLKILRKKDKIAILWGKLKSNSHPSLYTLSPSSV-----------KDYNEGFYLYRVPFLDEIRKFPSLLSYD-DGSEHKLDYDNMKKVTQSIMGYFNLRDGYNPSDFKNPLLQKHYKVLHDYLLQIETTFDENETPNTKKDRMMREDDSLRKLYY--------------------------IRNKILESEKSEDPIIQRLNKY--------VKIWNMFYKKFNDDNISIKEEKKPFDKKPKFNI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..: :. . ::.::* :: . : :: : . :: :. * ::. : : . . . . :. : : . ::.: :: .* .* . : . : ** . : : . . *: ::: .. .. . : :. :* : : *. : * :: :. :: : . . : . * :: :. .: . ... : ::**: : : : *: *:: ** : :* :. *: : : * :* * ** : :* .. * . . :: : . :** *... :::* *: * *:: : . . . * : * . : .* : . * : .. .:: .: ", "identical_positions": 38, "similar_positions": 148, "identity": "5.66%" }, { "cls_id": "homologset.agr.FB:FBgn0011785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZE0-1", "uniprot_id": "A0A8I5ZZE0_RAT", "id": "A0A8I5ZZE0-1", "name": "Bromodomain and WD repeat-containing protein 3", "aln": "-----MAAAP-TQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKNTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVK---TMKFRDRPVKFTERSRPG-VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLDMATKMSGNNLTST-EDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFG-CSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIP-----QLGYVANGDGEVVEQVIGQQTND-----QEESILDGIIRELQREQDLRLINEGDV-PH--FPINRSYSVNGALSSPNMDIPSSPNIGLRR-SGQIEGVRQMHNN--------------------------APRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKK--PSYPIQ------------RNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQ----NSGVQGDSDSSSEEDETVGTSDASAEDPVVEWQSES-SSSDSSSEYSDWTADAGINLQPPKRQ-TRQATQKIYSSSEDE----NVKSSEDRQKK-----------PKQTRKKKGGLVSMAGEPNE-------EWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIG--------DQSCTDILDTYNKIKAENPNSSDPEEDTEMVDLDSDGPGTSSG-RRAKCRGRR-----QSLKCNPDAWKQQCKELLSLIYEREDSEPFRQPADPHSHPAQQQ-EGESSESVPPDRQ-DPSLSEDYQDVVDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENRIKNIISEYKS--AIQSQKRRRPRY----------RKRLRS-------------------SSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVVYARTSSPFSSPVSDAAEGV----------SLYLLDDEGDGPFSPSSCSGYSRSG-----------NSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEED-----------------------------ESMGGEEKEMKETKEKAHLSSSESGELGSSLSSESTS-------GSDSDSESTSRTDQDYVDG-----------------------DHDYSKFIQTRPKRKLR--RQHATGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRG--------------------------------------------------------------------------------------------ASRGASRTKRARVADDEFDTMFAG------------RFSRL--------------------PRIKTRNQGRR--------TVLYNDDSDNDNFVSTEDP--------------------------------------------------------------------------------------------------------LNLGTSRS-GRVRKMTEKARVSHLMGWNY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHJ4-1", "uniprot_id": "BRWD3_MOUSE", "id": "A2AHJ4-1", "name": "Bromodomain and WD repeat-containing protein 3", "aln": "-----MAAAP-TQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVK---TMKFRDRPVKFTERSRPG-VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLDMATKMSGNNLTSA-EDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFG-CSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIP-----QLGYVANGDGEVVEQVIGQQTND-----QEESILDGIIRELQREQDLRLINEGDV-PH--FPINRSYSVNGALSSPNMDIPSSPNIGLRR-SGQIEGVRQMHNN--------------------------APRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKK--PSYPIQ------------RNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQ----TSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSES-SSSDSSSEYSDWIADAGINLQPPKRQ-TRQATQKIYSSSEDE----NLK-LEDRQKK-----------PKQTKKKKGGLVSMAGEPNE-------EWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIG--------DQSCSDILDTYNKIKAEDPDSSDLEEDSEMVDLDSDGPGTSSG-RRAKCRGRR-----QSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQ-DPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKS--AIQSQKRRRPRY----------RKRLRS-------------------SSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEGV----------SLYLLDDEGDGPFSPSSFSGYSRSG-----------NSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEED-----------------------------ESMGGEEKEMKETKEQVHLSSSESGELGSSLSSESTS-------GSDSDSESTSRTDQDYVDG-----------------------DHDYSKFIQTRPKRKLR--KQHTNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRG--------------------------------------------------------------------------------------------ASRGSSRAKRARVADDEFDTMFSG------------RFSRL--------------------PRIKTRNQGRR--------TVLYNDDSDNDNFVSTEDP--------------------------------------------------------------------------------------------------------LNLGTSRS-GRVRKMTEKARVSHLMGWNY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6RI45-1", "uniprot_id": "BRWD3_HUMAN", "id": "Q6RI45-1", "name": "Bromodomain and WD repeat-containing protein 3", "aln": "-----MAAAP-TQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK---TMKFRDRPVKFTERSRPG-VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLDMATKMTGNNLPSG-EDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFG-CSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIP-----QLGYVANGDGEVVEQVIGQQTND-----QDESILDGIIRELQREQDLRLINEGDV-PH--LPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNN--------------------------APRSQMATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKK--PSYTTQ------------RNDYEPSCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQ----NSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSES-SSSDSSSEYSDWTADAGINLQPPKRQ-TRQTTRKICSSSDEE----NLKSLEERQKK-----------PKQTRKKKGGLVSIAGEPNE-------EWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIG--------DQSCTDILDTYNKIKAEERNSTDAEEDTEIVDLDSDGPGTSSG-RKVKCRGRR-----QSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKS--AIQSQKRRRPRY----------RKRLRS-------------------SSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVSDAAEGL----------SLYLLDDEPDGPFSSSSFGGYSRSG-----------NSHDPGKAKSFRNRVLPVKQDHSLDGPLTNGDGREPRTGIKRKLLSASEED-----------------------------ENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTC-------GSDSDSESTSRTDQDYVDG-----------------------DHDYSKFIQTRPKRKLR--KQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRG--------------------------------------------------------------------------------------------ASRGATRAKRARIADDEFDTMFSG------------RFSRL--------------------PRIKTRNQGRR--------TVLYNDDSDNDNFVSTEDP--------------------------------------------------------------------------------------------------------LNLGTSRS-GRVRKMTEKARVSHLMGWNY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW9-1", "uniprot_id": "A0A8M9PQW9_DANRE", "id": "A0A8M9PQW9-1", "name": "", "aln": "-----MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSF---SMKFVDKPVKFMERSRPG-VQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQ-QEWKSTVLDMTTRLPGSAVISG-DDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFG-CSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVP-----QLGYMANGDGEVVEQVIGQQTADE---SQEESPLDDLIRQLQNQQDERVNQAN----------PAGAEVAGGPLSP-------PNVGLRR-SGQVEGVRQMHNN--------------------------APRSQMATERDLLAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQ------------PGDNVRTLRRPQRKAQQKR-HAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEQEEDQNENSDGTSEGETQWENDS-SSSDSSSEYSDWTADAGINLQPPKRT-TRRPARVAVSSSSEDEEGTGQGEGEAAQTT-----------KQAEKKKKPKQRSVPAGELE-------EWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIR--------DQNCTDILDLYNKMKSEFSSE---EDEEETVDVDSDTPGTSTGQRRSNSTPQK-----RGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYP-------------------------DYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKS--AVQNQRRSQ--------------QRLMC-------------------SKR-LQSSSPNSPKGKQKSGK---KTLQMSAKARTRKSSQDSN-VAQVDE-----------------DSQPSSSSSSSSSSSSSSSF-----------SSEQAGANRVTRSQVTSSKS----SGVFLPNGGRSSRR--RRAVLTE---------------------------------------EGEVSECESTSSSSSSTS----ASSSSSATS-------SSSSESDDSSAEVSGFADGG----------------------DHDYSKAPQHKQKGKAP--APPPPPSPPPPAPTIDNPKRKRKGEEEQSAEPEKRPRRTSSREEEEEEEEEEVDDEPEEE--------------------------------------------------------------------------------------------EEPDEEEEPEEEEEESDDENVISPSKRSNQ------RTPKS--------------------GRVNTRNQGRR--------TVLYNDDSEEE--GPTSDP--------------------------------------------------------------------------------------------------------LNLGMSRS-GRVRRMTERARVSHLMGWTH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LKM2-1", "uniprot_id": "A0ABK0LKM2_RAT", "id": "A0ABK0LKM2-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEAPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVDIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGD--RFLSGSRDGTARIWRFEQ-LEWKSILLDMAARISG-DTSAE-EERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVP-----QLGYVATSDGEVIEQVISLHTNDSGDASPESSVLDGMIRQLQQQQDLRLGVDQDV-TANGLPNEEGTPRRGSFRRLSLDIQSPPNIGLRR-SGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEAPPGVFRRLEDIRIERGEEERNLYVIGRKKK--TFQLPQ------------KSNSMVLVSQSRQRTCRRKYANYSRRNAGQCELSSGNE-----SSGSVRHETSCDQSEGSCSSEDDEWRSDRRSGSDSDSPSESSSQYSDWTADTGVHLEPPLRTSCRRRVTRFCSTSEDEMSTENISPPKRRRKR-----------RKESKPKRESLRRTTPAELANM-EPLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPSDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYSVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQRSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVHRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIK--------NQDCTNILELCN------TSDSD-GDSADDLD-DSDLPKTSSGRRRVHNWKRRS----RGSSCIESDWRRQCKALLILIFQCEDSEPFRQPVDLVEYP-------------------------DYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRF----------KQRQKCNGAVPVDRSMRSVKQKQFRSQTKVIPQLMCSPSQSTSSKVPLSATRKTSAGVSSGCTSGDSSDSAGSLERVRRHRAETLRSGSVLFGSEMEDFLATSSSSSSSNSSDESKESSGAQECSLRSGVLRSSNLRVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNHSVETDENLKS------KAGSSRKVLRKCAAVAASKIKLMSDAED-SSSESPCSGRKLPHRNASAVARKKLLHNSDD-QSLKSET--EEVRDRNQALLMSSPHAVQNCIS-----DSESDSDLQAARKTWHANGCTSHPAAACKAKSRPIESSEEDSRCHESDHGPSSTVDPLTSGQKLGADSISEEADSEPGSS------ALGKNTHLSKKAKILSDSEDCEEKYGER---RGPEVEGSPVSEALR-EAVIVPQCLSHHGPETDVDSDGSAVREKSHSNVNDSVSRENGQRKKVSRKRFCSSDSESNLQVIQKSPIDQTSPSRITRS-AGMVTDKTKLTSDAEDVSLESVCTRSKRRRKKPVRFACTTAKSIPSSEGKHARCEVPEEQSACRSSLAEPEQQGSAENASQAANADLDFEGSSSFEQTKSIQKRQMDSVCIRAPSKTQNSSAGPSQEDPKSHTQDSDIS--LSSESVLAQKAIGENNFEEELNYGLRRWNGRRLRTYGKAPLSRTAPVTPSLQAAAEVRVKRRRVHPEVDGEDIPGQMGSSGCGPDTSPKSSDLGSVTESDVDCTDNTKAQRRKKRKGKTRVLSQESVRKDREPHTKTRPCMFNEKEAVQMHSDTLKPKTVPEKIPRRCAAIAANKIKTMCNLKEVVSGPENVGIRTNSRKLPYRQASAAAKKKLLSVYKEDDALIHSENEEE--------VYLRRFRSQKEKAQQSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921C3-1", "uniprot_id": "BRWD1_MOUSE", "id": "Q921C3-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEVPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVEIHRGRQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFDAPEKIAELESHTDKVDSIQFCNNGD--RFLSGSRDGTARIWRFEQ-LEWRSILLDMSARISG-DTSSE-EERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVP-----QLGYVATSDGEVIEQIISLHTNDSGDASPESSVLDGMIRQLQQQQDQRLGVDQDG-TANGLPSGEGTPRRGSFRRLSLDIQSPPNIGLRR-SGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEAPPGMFRRLEDIRIERGEEERNLYVIGRKKK--TFQVPQ------------KSNSMVLVSQSRQRTCRRKYANYSRRNADQCELSSGNE-----SSGSVRHETSYDQSEGSCSSEDDEWRNDRRSGSDSDSSSDSSSQYSDWTADTGINLQPPLRMSCRRRVTRFCSTSEDEMSMENISPPKRRRKR-----------RKESKPKRESLRRMTPAELANM-EHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQEGEWGQRSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIK--------NQDCTNISELCN------TSDNDEDDSADDLD-DSDLPKTSSGRRKVHNWKRRS----RASGCIESDWRRQCKALLILIFQCEDSEPFRQPVDLDEYP-------------------------DYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRF----------KQRQNCNGAVPGDRRRRNVKQKQFKSQTKVIPQLMCPPSQSTSSKVPLSATRKTSAGVSSGFTSGDSSDSAGSLERVRRQRPEVLRSGSVLFGSEMEDFLATSSSSSASNSSEESKASPGARESSLRSGVLRGSNLGVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNNSVETDENLKNR-----KCGSSRKVLRKCAAVAASKIKLMSDAED-SSSESPCSGRKLPHRNASAVARKKLLHNSDD-QSLKSET--EELKDQNQSLLISGPHSVHNSIS-----DSESDSDLRATRKTWNANGCTSHTAATCKTKSRPIESSEEDSRCHGSDHGPSSTGDPSTSGQKLRADSISEEADSEPESS------VLCKNTHLCKKAKILSDSEDCEEKCGER---RGPEVEGSPVSEALR-EAILAPQCLSHRGSETDVDSDGGAVREKSYSNENGSVSLENGQRRKVSRK--SSSDKESNLQVTQKSPKDRSSPSRITQR-ASVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQPACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSSAGLSQENARSQTLDSETS--LPSESVLTQKATVESNFEEELNYGLRRWNGRRLRTYGKAPLSRTAQVTPSLQASAEVGVKRRRMHPEVDGEDVPGQMGSSGCGPDTSPKASDLGSVTDSDVDCTDNTQTQRKKKRKGKARVLSKESVRKDREPHTKMRPCMLNEKDAVQMHSDTLKAKTVPEKVPRRCATVAANKIKMMCNLKEVVSGPENVGIRTISRKLPYRQASAAAKKKLLSVYKEDDAPIHSENEKE--------LYLRRFRSRKEKAQPTPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSI6-1", "uniprot_id": "BRWD1_HUMAN", "id": "Q9NSI6-1", "name": "Bromodomain and WD repeat-containing protein 1", "aln": "MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLE---SLKFSPRPLKFTEKPRPG-VQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGD--RFLSGSRDGTARIWRFEQ-LEWRSILLDMATRISG-DLSSE-EERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFG-CSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIP-----QLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDT-IPRGLSNGEETPRRG-FRRLSLDIQSPPNIGLRR-SGQVEGVRQMHQN--------------------------APRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRK--TLQLSH------------KSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNE-----SSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDEISTENLSPPKRRRKR-----------KKENKPKKENLRRMTPAELANM-EHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIK--------NQHCTNISELSN------TSEND-EQNAEDLD-DSDLPKTSSGRRRVHDGKKSI----RATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYP-------------------------DYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRF----------KQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRP--ITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKA------RAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIE-KPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHK----HRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDS-QETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRK-TKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QKF7-1", "uniprot_id": "A0A8M1QKF7_DANRE", "id": "A0A8M1QKF7-1", "name": "", "aln": "MADTTARNGSISPLESELYYLISRYLSTGPCRKAAEALVCELEENQLLPRRLDWEGNEHPRSYEDLVTANRHIAPDHLLQICKQIGPVLDREVPSGVPGVHSLLGAGRHSLLRTSKDCCASRWKTSTFAALHRGRPPERPLNC-KDANIVEVCRGRELTGAQRFSSINPVSNYQHMKMHRRILGHLSAVYCIAFDRTGSRIFTGSDDALVKIWSSFDGRLHSTLRGHYAEISDLAVNFENTLIAAGSCDKTIRVWCLRTCAPVAVLQGHSGSITSLQFSPFVKGSKRYMVSTGTDATVCFWQWDVN---NNEFSDRQHKFTERPRPG-VQTVCSSFSPGGMFLATGSTDDVIRIYYLGSGSPEKLAELDSHTDKVDSIQFCHSGE--RFVSGSRDGTARIWRLHQRHQWKSVLLDMSATLPGSAPLTD-DENFFKPKVTMVSWDRHDNTVITAVNNHLLKVWNSYTGQLLHVLKGHEAEVFVLEPHPYDPRIMLSAGHDGNVFVWDLIKGTKTMHYFNMIEGQGHGAVFDCKFTPDGHRFAMTDSHGHLVIFGFG-SSKPYEKLPDQVFFHTDYRPLIRDTNGFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENIADEHLVP-----QLGYVATSDGEVVEQVISQQSAESE--EVRHSALDFAIRQLREHQDRQSGAPGEAGVPAAARVPEPGTPRRVSVNERMEVQSPPNVGLRR-SGQVEGVRQMHQN--------------------------APRSQMATERDLQAWRRRVVIPELTPSGYRAQESFRIAKGDEEVNLYNTKKRRVTHSTFRDD------------SDEEGPCLKRTQSRKRQKNQERKENLAEEYIEFSCEEG----------EETASSEASEVEGSDIDSSAEDEEEWKSDS--SSRSSSDYSDWTADAGISVRTSDSS--RRRTTRRISSSEEEDEEDDEEEEEPADEEPAVGEEETSSPRKHKKAKSKTPKHSKPRPSINR-EISNEFRPPAWITDVVPRKSPFVPQMGDEVIYFRQGHEAYVDAVCRMNLYPINLDKQPWKKMQLRDQEFVKITGIKYEVCPPTLCCLKLTQIDPGTGKITDRTFSIKYHDMADVIDFLVLRQSYDEARNRVWTSNDRFRSVIDDAWWFGAIVCHEPYQSEYPDSHFQCFKVKWDNGETEKLSPWDVEAIPENAEQPESASAGVPVTDEEMMDILYKPQRGEWGDRGREQESARIIAGIEQLMTVDITAPFSGPVDLTQYPTYCTVIAYPTDLNTIKLRLKHNFYRRLSALIWDVKHIEQNAKTFNEPRSKIAQSAKIITNVLIKFIS--------KLHCTDIMEIYN------AVENMEYSDDEEMD-DIDAPGTSAGQRLRQ----PS----VEVVLDRDAWKDHCKRLLDYMFECEDSEPFRDPVDQSDYP-------------------------DYTNIIDTPMDLGTVRQTLEEDRYENPIDVCKDIRLIFANAKAYTPNKRSKIYSMTLRLSAFFEENIRKIISDYKTAIKSSLKLRRSQRC----------RKKSQH---------------------QESVSFSQGSTRQKRATIKTQENTEQSTAKSTSAKVSGPERRRAHEAKETFRRSS----SSSSGSDQDSKQSLSQSDEDDEHSSS-----------SRAMRRETRATRKKAAQNKGAKSRRPESHVKMNGRSRSHERQKPRTSSDSDHEPSQGSDEASENESSPSVSRRPRTRKTAMAAVNKMKLIDTLGDEEGTDDEGGGGSTRPATRASKRSAVIQSSSDSDDEEEAAASQEESNESGSSASEGEKSAG----------SADSDSSSHSKKNSRTAGRRPCRRPAEKKETSPLTNGHGTKRQWEESDDNSEDGGSPIESENLESDNDLVVRRKSTRRTAK--------------------------------------------------------------------------AAVSKIKKINNTDAEEEENCTRDRRQKHRSITQESENSSDEEVETTKTLKHPHQNGRK--------------VDAKELKRCKAPSERQEQSPAAKQKTTHKKSSATDACMSTTQDSEELSDDVEKSVTHRKRIASEDEENQSDDADQRRVPKNRNRSSNARKQKLCASSDESSSESDEKADRGRIKSEGTSSDEWQKS-------------------DTSEEDKKTHPQRKPCPTVASKGVSLRTRPKKNYIMEDSEEEFSPKMDVQAKNGVKNQQANSRTRKPSGGGFKRKHGGSSESDADSKSSRSSDGNKLAEAQRKSAKRFKQLMGSTDSESDFETRCKSENGRAQRSQGKLPTVSRQRRKQSESDKGSNDNGSNFESEESESEASSGSRSSPKRRLRDRDRGTARSRKPRRVVSDDDSDVSFEKPRRGRRIQTRNKGKRTVNYQDSE-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M3B3-1", "uniprot_id": "F1M3B3_RAT", "id": "F1M3B3-1", "name": "PH-interacting protein", "aln": "---MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPNIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG---TLKINPRPTKFTERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN--RFVSGSRDGTARIWQFKR-REWKSILLDMATRPAG-QNLQGIEDKITKMKVTMVAWDRHDSTVITAVNNMTLKVWNSYTGQLIHVLTGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLVIFGFG-SSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIP-----QMGVTSSG----LNQVLSQQAIQ------DISPLDSMIQRLQQEQDLRRSGEA--------AVSSAGRLNRGSVSSTSEVHSPPNVGLRR-SGQIEGVRQMHSN--------------------------APRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILT-----VSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEE----IENGTSSSD-EGEVLAVSGGTSEEE---ERAWHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKQDSSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNRIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKHQHFLLFRDQTCYNIIPLYNSMKKKVLSDS------EEEEKDADVPGTSTR--KRKDHQPRRRLRNRAQSYDIQAWRKQCQELLNLIFQCEDSEPFRQPVDLLEYP-------------------------DYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRR----------KRRNRS---------------------SSLSSSAASSPERKKRILK---PQLKSEISTSPFSIPTRSVLPRHSAAQMN--------------GKPESSSVVRTRSNRIAVDP----------VVTEQPSTSAATKAFVSKTNTSAMPGKTILENSVKHSKALSTLSSPDQLTFSHGTKNNSAKEN----------------MEKEKPVKRKMKSSVFTKASPLPKSSAVVDQGDCKNNVLIPGTIQVNGHGGQPSKLVKRGPGR----------------------KPKVEVNTSSGEVTHKKRGRKPKNLQCTTKQENSEQNNMHPIRGDVVPSSTCSFLSETNVVKEDLLQKKSRGGRKPKRKMKTQN--------------------------------------------------------------------------------------LDSELIVPTNVKILRRSNRKKADDPIDEE------EEFEELKG--------------------SEPHMRTRNQGRR--------TAFYNEDDSEEEQRQLLFEDTS-----------------------------------------------------------------------------------------------------LTFGTSSR-GRVRKLTEKAKANLIGW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDD9-1", "uniprot_id": "PHIP_MOUSE", "id": "Q8VDD9-1", "name": "PH-interacting protein", "aln": "---MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG---TLKINPRPTKFTERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN--RFVSGSRDGTARIWQFKR-REWKSILLDMATRPAG-QNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFG-SSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIP-----QMGVTSSG----LNQVLSQQANQ------DISPLDSMIQRLQQEQDLRRSGEA--------GVSNASRVNRGSVSSTSEVHSPPNIGLRR-SGQIEGVRQMHSN--------------------------APRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILT-----VSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEE----LENGTSSSD-EGEVLAVSGGTSEEE---ERAWHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKPESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRPWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIK--------DQTCYNIIPLYNSMKKKVLSDS------EEEEKDADVPGTSTR--KRKDHQPRRRLRNRAQSYDIQAWKKQCQELLNLIFQCEDSEPFRQPVDLLEYP-------------------------DYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNFKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTISKKR----------KKRNRS---------------------SSLSSSAASSPERKKRILK---PQLKSEVSTSPFSIPTRSVLPRHNAAQMN--------------GKPESSSVVRTRSNRVAVDP----------VVTEQPSTSSATKAFVSKTNTSAMPGKAMLENSVRHSKALSTLSSPDPLTFSHATKNNSAKEN----------------MEKEKPVKRKMKSSVFSKASPLPKSAAVIEQGECKNNVLIPGTIQVNGHGGQPSKLVKRGPGR----------------------KPKVEVNTSSGEVTHKKRGRKPKNLQCAK-QENSEQNNMHPIRADVLPSSTCNFLSETNAVKEDLLQKKSRGGRKPKRKMKTHN--------------------------------------------------------------------------------------LDSELIVPTNVKVLRRSNRKKTDDPIDEE------EEFEELKG--------------------SEPHMRTRNQGRR--------TAFYNEDDSEEEQRQLLFEDTS-----------------------------------------------------------------------------------------------------LTFGTSSR-GRVRKLTEKAKANLIGW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWQ0-1", "uniprot_id": "PHIP_HUMAN", "id": "Q8WWQ0-1", "name": "PH-interacting protein", "aln": "---MSCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG---TLKINPRPAKFTERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN--RFVSGSRDGTARIWQFKR-REWKSILLDMATRPAG-QNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFG-SSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIP-----QMGVTSSG----LNQVLSQQANQ------EISPLDSMIQRLQQEQDLRRSGEA--------VISNTSRLSRGSISSTSEVHSPPNVGLRR-SGQIEGVRQMHSN--------------------------APRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRKHLTVPKENKIPT-----VSKNHAHEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEE----IENGSSSSD-EGEVVAVSGGTSEEE---ERAWHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKNKTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGELTENGLTLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIK--------DQTCYNIIPLYNSMKKKVLSDS------EDEEKDADVPGTSTR--KRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYP-------------------------DYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRR----------KKRNRS---------------------SSVSSSAASSPERKKRILK---PQLKSESSTSAFSTPTRSIPPRHNAAQIN--------------GKTESSSVVRTRSNRVVVDP----------VVTEQPSTSSAAKTFITKANASAIPGKTILENSVKHSKALNTLSSPGQSSFSHGTRNNSAKEN----------------MEKEKPVKRKMKSSVLPKASTLSKSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGR----------------------KPKVEVNTNSGEIIHKKRGRKPKKLQYAK-PEDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDLLQKKNRGGRKPKRKMKTQK--------------------------------------------------------------------------------------LDADLLVPASVKVLRRSNRKKIDDPIDEE------EEFEELKG--------------------SEPHMRTRNQGRR--------TAFYNEDDSEEEQRQLLFEDTS-----------------------------------------------------------------------------------------------------LTFGTSSR-GRVRKLTEKAKANLIGW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PE61-1", "uniprot_id": "A0A8M9PE61_DANRE", "id": "A0A8M9PE61-1", "name": "PH-interacting protein", "aln": "---MAAERKHVAQLKSELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRIDWTGKEHPGSYENLVKLYRHISPDHLLQVCERVSPLLEREVPASVPGVNSLLGTGRQSVLRTNKSCKHVVWKGSALAALHCGRPPEPPVIFGSPPNIAETIHSRRLNGSYRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDAR---TLKFGQRPSKFIERPRPG-VQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGD--RFVSGSRDGTARIWQLQQ-QDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFG-SSSRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIP-----QMGLTSSG----LNQVVSQQAAE------GSSPLDSMIQRLQQEQDQR--------------LGSDSRANRGSVSSPTEVTSPPNVGLRR-SGQIEGVRQMHSN--------------------------APRSEIATERDLVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRRSLHSQYHR----------ENRHAIENAAEEG--RRHQGNQHNYHTRLAVEETSRQSEP----NEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADAGINLEPPKKTSVKKKKKKNASSSEED---GEKKKDSKKERRKEKPDKDG-ALPKKKKPKEKRKR---IPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIK--------DQSCTDIIPLYNSMKKTAFSDSS-DDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYP-------------------------DYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQSLHSERLTRQRLHTDRLTRQSVKKRRRR---------------------SSSHSSSASSPERKRRVSSRAPPRLDSAAPPTPAG-PSRAPSLRQTHPQIN--------------GKAETPVVPGRTRSSARFGS----------PITDVAPAQSAPPPLVESSSS------RVLRTQNPHSTAVSRENESSAVPPSNGG---GARE-----------------------SRRKLRTPVKLTPGPVDHSSPPQN------------SLHLNGHSQVTVGMVRRGRGRPRL-------------------DTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSH---EEELMLPTGDDGGASSTAQDSNLSDSGEYPKARGRPRITKT--------------------------------------------------------------------------------------IDTP--APPSPKTLRRSSRRGNEEITPHTSGSAQSEEPEVYIGED----------------GSSKGQMKTRNQGRR--------TAFYNEEDSEEEQRQLLFEDAS-----------------------------------------------------------------------------------------------------ITFGTSSK-GRVRKLTEKAKANLIGW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC96-1", "uniprot_id": "Q9VC96_DROME", "id": "Q9VC96-1", "name": "", "aln": "--METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDS-VLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRGL--RFISGSKDGTAHIWTFES-QQWKSSKLCMTERLASCPEPEE----GKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEEEDVSSNSSGDTSYSNVEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDSSDDERAGRSRGGQVT----------------ARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIID-EEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPIDQQR-VPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIR--------EPDEIDVAAVYHQLADVYHSSES-ENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFP-------------------------DYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSSSSPNKRVKK----------------------ERSTRRNQKPTAAARRLPVANSSEDEDEEDDDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSE-----------EEEEEETSAQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKSPANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSS--LESPSRNTRANGTRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILP----------------------------------------------------------------TPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDDDDDSDNEPLANNQQKNYQSPAKS---------------SSTATVAPHPLSLRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQPAVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTS--------------------------------------------------------------LDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPRRKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..***:**:::* ** . :*: *: *: : :::*:* . *::. :::: *: .::**.:* ::.*::::. * .:. : :***.**:.:** : . : *: *: : .: .:. * * *:: *: :* :****:***: ***:* *:**:** *:***:: :*:* :**** :**:*:::* :**::*:.* *: :*** ::* :*:***..*:. ***::*.* . ::: :*.:*. :.** : . : : :: *: *** .* *::** **:*:::*.:*. :*:* :* * :: : : :** * ::*:.: **:***:****:** . :*:* * *: .. : ***::*: * ::**..: :*:*.* ..:* : * ** *::***.:* * ::::******. :**: :* ::* *:*****:***.* : ** :* ******:::**:* . . *. :. ::***:*:***:**:: .*:***** ***********.******.: **:*****. ::*:* * . : ::. . : : . . * . : .:: * * . * . . : : **. : : *: * . * :: : . : . .. ** **** **: . .: :..:. : : .. *: :. *:.*: ******: ****** *: . . : :. .:**. **::* ::: *::**: * ******: :* *.: . :*.::****.**:*****:* :: * * * :***.:* *.**:* : .:.. . ::*** * *: * *** : * :****:* : : *:. . .:.: * :*.* ** *: . *:: .:::: :..: * **:* ** *. :: * ** **: *: :.****.:: ::*::: *:. :*. : *. :: ::: :::* . :: : . : . .: *: *. *: : ** ***:*.* .* ** : : **:*: ** : * ..* *::. **:* ** * * *...*:*:**:* * ***:**..: : .:* . :: . . . . . . . : . . . * . ", "identical_positions": 379, "similar_positions": 418, "identity": "15.34%" }, { "cls_id": "homologset.agr.FB:FBgn0011787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DB15-1", "uniprot_id": "RM12_MOUSE", "id": "Q9DB15-1", "name": "Large ribosomal subunit protein bL12m", "aln": "-------------------------------------------------------------------------MLPVAASRC--LWGPRLGLRGAALRLARQQMPSVCAARQLRSSSHRRSEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLMPMGGMVPGPVSAAAPASEAAE------EEDVPKQKERTHFTVRLTEAKPVDKVKLIKEIKNYVQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZXF9-1", "uniprot_id": "D3ZXF9_RAT", "id": "D3ZXF9-1", "name": "Large ribosomal subunit protein bL12m", "aln": "MPRRAAGESSDPVLFPGPDCVCASRRLVRNIRSQPSRPGRQGLVARAARPARLLPDRASLPLRAACDLPACGAMLPAAAAAASRLWGPRLGLGGSALRLVRQQMPGVCVARQLRSSSHRRSEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLMPMGGMVPGAVPAAAPAPEAAE------EEDLPKQKEQTHFTVRLTEAKPVDKVKLIKEIKNYVQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52815-1", "uniprot_id": "RM12_HUMAN", "id": "P52815-1", "name": "Large ribosomal subunit protein bL12m", "aln": "-------------------------------------------------------------------------MLP-AAARP--LWGPCLGLRAAAFRLARRQVPCVCAVRHMRSSGHQRCEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLVPMGGVMSGAVPAAA--AQEAV------EEDIPIAKERTHFTVRLTEAKPVDKVKLIKEIKNYIQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53163-1", "uniprot_id": "MNP1_YEAST", "id": "P53163-1", "name": "Large ribosomal subunit protein bL12m", "aln": "------------------------------------------------------------------------------------MSLRILAKRSSSIWMKTRVTPALISPITITTRFN--STTTTAPSHKDDVRPVDPKISKIVQDISQLTLLETSSLINELKTVLNIPEIS-MPMGGFMAGAAGAGAGNVPSSTGEAGSGAEEEAKPEAKTVFTVKLDSFDTKTKAKVIKEVKG-LLGLSLVEAKKFVEAAPKVLKENVAKDDAEKIKKTLEDLGAKVSLE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VSR5-1", "uniprot_id": "Q9VSR5_DROME", "id": "Q9VSR5-1", "name": "", "aln": "------------------------------------------------------------------------------------MHITRLALRQISRQVQLHRMYSAAAP----AAAVSGAEKLVPPAPEGAAKPPNPKLDSIVNNIAALNLLEVAELSTLLKQKLNLPETAFAPQFAAGPARAAPAED------------EEEAAPKKVQTSFKVKLVKFDEKQKVALIKEVKNLLEGMNLVQAKKFVESAPTIVKEDIPKEEAEKLKEALSKAGAIIEIE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. : : : : . . .. .. : **:..:*::*: *.*** :.* ** *:: : . * . .. . .. *: . : :* *.*:* . . *. :***:*. : *:.**:***:**: * :* ::.* :***:* :*. *. : :*", "identical_positions": 42, "similar_positions": 62, "identity": "14.89%" }, { "cls_id": "homologset.agr.FB:FBgn0011802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAM8-1", "uniprot_id": "F1MAM8_RAT", "id": "F1MAM8-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "-MAAAFEALPASTTSESAMAAELEAAPVPAAEPTPASPWNLRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEILANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCN--INLLPLP-DPIP------------------AGLMEECLDCDVEVKAAMHTYSSPSISTQSPKKQVQKPERAFQSQRTPGSHMPSPRNTSVSTLSAKSKHG-KQKLPVKSHSECGILEKAAPPQELGCTTHPEEQVKNSVQTSTEESSSNSLHQ---------------------------------------AKETSPGSLPKIPCLSSFKVHQL----------------------------------SALTFAELVEDYEHYIKE-----------------GLEKPVEIIRHYTGPGAQTVNPQNGFVRNRVSADRVQMLVSSSQSGDSESESDSCSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDTQLKDSECTSVGGPLSLEQIQNG-------NDTSTQVEYQESPETQVKARHKEGANQ----------RSKPSRRNPPRRSSYRVQTE-AQEEGWHDCHRETNASSSDPYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTVYLQEMMRGNQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJY4-1", "uniprot_id": "DDX20_MOUSE", "id": "Q9JJY4-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "MAAAAFEVPAALTTSESTMAAERAAAPVQAVEPTPASPWTQRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEVLANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKVPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCN--INLLPLP-DPIP------------------PGLMEECLNWDVEVKAAMHTYSSPTVATQSPKKQVQKLERAFQSQRTPGNQTPSPRNTSASALSARPKHS-KPKLPVKSHSECGVLEKAAPPQESGCPAQLEEQVKNSVQTSVEDSSSNSQHQ---------------------------------------AKDSSPGSLPKIPCLSSFKVHQP----------------------------------STLTFAELVDDYEHYIKE-----------------GLEKPVEIIRHYTGPEAQTGNPQNGFVRNRVSEDRAQMLVSSSQSGDSESDSDSCSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDTQLKDTECTPVGGPLSLEQVQNG-------NDTPTQVEYQEAPETQVKARHKEGANQ----------RSKQSRRNPARRSSYRVQSE-PQEESWYDCHRETTASFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTVYLQEMMRGNQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHI6-1", "uniprot_id": "DDX20_HUMAN", "id": "Q9UHI6-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "-MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCN--INLLPLP-DPIP------------------SGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGLSVKSKNNTKQKLPVKSHSECGIIEKATSPKELGCDRQSEEQMKNSVQTPVEN-STNSQHQ---------------------------------------VKEALPVSLPQIPCLSSFKIHQP----------------------------------YTLTFAELVEDYEHYIKE-----------------GLEKPVEIIRHYTGPGDQTVNPQNGFVRNKVIEQRVPVLASSSQSGDSESDSDSYSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDNQLKDSESTPVDDRISLEQPPNG-------SDTPNPEKYQESPGIQMKTRLKEGASQ----------RAKQSRRNLPRRSSFRLQTE-AQEDDWYDCHREIRLSFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTIYLQEMMHSNQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW1-1", "uniprot_id": "A0A8M9PQW1_DANRE", "id": "A0A8M9PQW1-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "--MCAQEGAVIHSSCHLFTVEETERCRDRNMAAS------VKAAHELQS-RTRTDDVLISGGVEFSSLLLSKPVLEGLSASGFQRPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFTTIALDSLILENATTQVLVLAPTREIAVQIHAVVMAIGSAMEGLECHVFIGGRPISQDKQHLKKCHIAIGSPGRIKQLIEMGALMVSSIRLFVLDEADKLLEDDSSSSFQEQINWIYSSLPANKQMLALSATYPESLAQQLSRYMREPTFVRLNPTDPGLLGLKQYYKIVPSHSLPHKVFEEKVQSLLELFSKIPFNQALVFSNLHTRAQHLADILSSKGLPAVCISGGLSQDQRLEAMWKLKQYQCRVLISTDLTSRGIDAEKVNLVINLDVPQDWETYMHRIGRAGRFGTLGVAVTYCCHGEEENKMMAIAQKCS--LDLMHLP-DPIP------------------PGIMEEACDHDVII----ETLSKPKIPDN-FKPEKKKKAKSEQMKSKP------SRESHISVVITESVTG------DKSCSRAETKTKNHSSK-------PGRQKQMAPAANLQHDSTITQKQ---------------------------------------QND----TLPKIPPLSSFKSHTG----------------------------------KRITFDDALVDYETFIRE-----------------GPGRSVEIIHQYDGFYRSQDKVNGLHDAHDEDEASESYVLEESQSHQDLPPAQEVSELSS---------------------------------------------------------------------------------------------EQKTSSESSSE--SEMEVESESSSSVPSKSTLEALPDNKVSLVRNHSELAELALPSTRVPQQATRSKKRPCQP---------QSQDTAHHHNLPHKHRTASK-SSRRPTGPKRRTRETDETEEEEAGQDYWSS-YRAWAEYYN----SYYHH--------------SPYN--WMTAFYMNSVYIKEMMKH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3C4-1", "uniprot_id": "DDX20_DROME", "id": "Q9V3C4-1", "name": "DEAD-box RNA helicase gemin3", "aln": "--------------------------------------MEREIAHSLAGGEERSSDVAPGQVKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESRVIIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQT---KSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPMPNEFNFWDFEKYNFDYYIKEENPLQEMPMPIKENRSKENVDASSVDLENLQKDQDGKRRDPDKLPVALENVETQKELELENLPESSHNNKNLRVKEKEIVRQGKLKETNSKAGGSKTNKTERRKKSNTPSKLQKQITEVQQTPEITVNKYYMQEDIQRTADGKEYHPVNGAGNHQVPSKSNQKPVEFISPELTPTLTPLELTQEPSPTTVTPPAPPANSINNKTYCLAAPTQTSSMTIQNMVISNTVDDASSISSDSMVVCGYHSDRSYDTYYATSDEEEIWNRLMSKQRRQLKSKRGHGKRRVILYKKVFPKLKANVKRKLKKRMSSSCRSKKAHHLRKRHVYKNISLLPHMNLCHLLQKFTNQERFLKRLHKYAKNQFIDNARVGFLLDKLYKSILEMYYNSAKERKKHFKEAMKESLKSIDNYESQESSESEEEEEEEKDLKNKLSVHVTNQMDIPPMPQAAVEIGSGSESDTEDSQEYGEGEEIIVDDEDDGSDGGPNSSSGFVESQESVSSGIDTSVYETESTGASGNNSSAFFISDDESDTESLTDSEAGSNVSATGSSSQRSSVASSTYESSDDDSVTVTNVSSMQNAQSLWLQTFNMQYQFIASHVAKNLQNYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:.: . . *:.** . *..* * : :*:** .* *: :* ***:. . :***:*:******* :: .::*: : .: :::.****:*:*:: .. : :..::* .**** :::*: ::::.:: :*:***: :* * : ..:**::*****:* : *:*. :. : .::* .:*::* **** : * : *:: * .* :: . . *:*::*: : . . : :. * * * ::*.::*::**::*:. : **: : *::.*: *** :.*.:**..: ::: *:*::*** :**:*: :.***:*:* * * **:**********: *:::*: . :*.: : :::* .:: :* :*:* : : .. . ..: : : : . : : :: . : . . *. . : . .: : : :. : : : : * *:.:: :.: : : * . : . ** .: . : : . . .:: . . * :. ... ..:* * .: :::. . * . : : . : . :. : .:: : .. : .. . :: : . . * * : *: :: *: :: . : ", "identical_positions": 136, "similar_positions": 267, "identity": "12.72%" }, { "cls_id": "homologset.agr.FB:FBgn0011817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSZ3-1", "uniprot_id": "NLK_RAT", "id": "D3ZSZ3-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSV--TDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDN---VLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDT---------FEKNLSSVRQVKEIIHQFILEQQKGNRVP------------------LCINPQSAAFKSFISSTVAQPSEMPPSPLVWE--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AJX5-1", "uniprot_id": "A0A8I6AJX5_RAT", "id": "A0A8I6AJX5-1", "name": "Mitogen-activated protein kinase", "aln": "MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHH-PQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGLAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSV--TDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFIHDN---VLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQ----------------------------------QPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDT---------FEKNLSSVRQVKEIIHQFILEQQKGNRVP------------------LCINPQSAAFKSFISSTVAQPSEMPPSPLVWE--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54949-1", "uniprot_id": "NLK_MOUSE", "id": "O54949-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSV--TDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDN---VLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDT---------FEKNLSSVRQVKEIIHQFILEQQKGNRVP------------------LCINPQSAAFKSFISSTVAQPSEMPPSPLVWE--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBE8-1", "uniprot_id": "NLK_HUMAN", "id": "Q9UBE8-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGARANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSV--TDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDN---VLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLAR---VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDT---------FEKNLSSVRQVKEIIHQFILEQQKGNRVP------------------LCINPQSAAFKSFISSTVAQPSEMPPSPLVWE--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4D6K823-1", "uniprot_id": "A0A4D6K823_DROME", "id": "A0A4D6K823-1", "name": "Mitogen-activated protein kinase", "aln": "MSVS--------MSLVQGG-----------------------------------------------------AAGGAPQGASAIL--------------------AAAAP--------------YYQPPAVPQ---DVQPDRPIGYGAFGVVWAV--TDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHEN---VLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLAR---VEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPFDDL---------WERKLTSVQQVKEEMHKFIAEQLQTGRVP------------------LCINPQSAAFKSFASSTVAHPSELPPSPHQWEXRQNEAIAA-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00772-1", "uniprot_id": "SLT2_YEAST", "id": "Q00772-1", "name": "Mitogen-activated protein kinase SLT2/MPK1", "aln": "--------------------------------------------------------------------MADKIERHTFKVFN-----------------------------------------------QDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGS-INGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVN-LYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVNDMEDLKQMVIQEVQDFRLFVRQPLLEEQRQLQLQQQQQQQQQQQQQQQQPSDVDNGNAAASEENYPKQMATSNSVAPQQESFGIHSQNLPRHDADFPPRPQESMMEMRPATGNTADIPPQNDNGTLLDLEKELEFGLDRKYF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: : **:**:*:* :. ::. :. **:**:.***.. : .** :****:* .* .: * :**: *. . :: :*: **::.*:*:** * * *: * : * **** ****:*** :****:********::* ********** : ::::.:*: *.*::******::. : *:.*:*:**.***:.*:** : :*:.:. :: *....: * .:*. :*:.** :**.***.***:. :** ****. : . :*. * * *:: . .:* *:. .::* :: :: :* : . * .: **. :* . .. : :::** * ", "identical_positions": 127, "similar_positions": 128, "identity": "21.13%" }, { "cls_id": "homologset.agr.FB:FBgn0011818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYE5-1", "uniprot_id": "OAF_RAT", "id": "Q6AYE5-1", "name": "Out at first protein homolog", "aln": "------------------------------MRPPGRRDVPSAR--------------PALPLLLLLLSPLLLGAPHGVGASSGAPAELRVRVRLPDGQVTEESLQADSDADSISLDLRKPDGTLISFIADFKKDVKIFRALILGELEKGQSQFQALCFVTRLYHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEQLHMDIAVNFSQGGLLSPHLRNVCAEATDAIYTRQEDAQFWTER-GVDSSVFEPLLKELEQVELPRCGQVGDRGKPCICHYSLSLAWYPCMLKYCHSR-------------DRPAPYKCGIRSCRKSYRFDFYVPQRQLCLWDE------------------------DP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZR4-1", "uniprot_id": "OAF_MOUSE", "id": "Q8QZR4-1", "name": "Out at first protein homolog", "aln": "------------------------------MRPPGCRDVPSAR--------------PALPLLLLLLSPLLLGALHGVGAGSGAPAELRVRVRLPDSQVIEESLQADSDADSISLDLRKPDGTLISFIADFKKDVKIFRALILGELEKGQSQFQALCFVTRLHHNDIIPSEAMAKLRQKNPRAVRQAEEVRGLEQLHMDIAVNFSQGGLLSPHLHNVCAEATDAIYTRQEDVQFWTER-GVDSSVFEALPKALEQAELPRCGRVGDRGKPCTCHYSLSLAWYPCMLKYCHSR-------------DRPAPYKCGIRSCRKSYTFDFYVPQKQLCLWDE------------------------DP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UD1-1", "uniprot_id": "OAF_HUMAN", "id": "Q86UD1-1", "name": "Out at first protein homolog", "aln": "------------------------------MRLPG---VPLAR--------------PALLLLLPLLAPLLG---------TGAPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLVSFTADFKKDVKVFRALILGELEKGQSQFQALCFVTQLQHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEHLHMDVAVNFSQGALLSPHLHNVCAEAVDAIYTRQEDVRFWLEQ-GVDSSVFEALPKASEQAELPRCRQVGDHGKPCVCRYGLSLAWYPCMLKYCHSR-------------DRPTPYKCGIRSCQKSYSFDFYVPQRQLCLWDE------------------------DPYPG------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NLA6-1", "uniprot_id": "OAF_DROME", "id": "Q9NLA6-1", "name": "Out at first protein", "aln": "MILKEEHPHQSIETAANAARQAQVRWRMAHLKALSRTRTPAHGNCCGRVVSKNHFFKHSRAFLWFLLCNLVMN------ADAFAHSQLLINVQNQGGEVIQESITSNIGEDLITLEFQKTDGTLITQVIDFRNEVQILKALVLGEEERGQSQYQVMCFATKFNKGDFISSAAMAKLRQKNPHTIRTPEEDKGRETFTMSSWVQLNRSLPITRHLQGLCAEAMDATYVRDVDLKAWAELPGSSISSLEAATEKFPDTLSTRCNEVSSLWAPCLCNLETCIGWYPCGLKYCKGKGVAGADSSGAQQQAQPTNYRCGIKTCRKCTQFTYYVRQKQQCLWDEXRRGELQLMQMRCARRRNGSEFGDDASATCPGGETRAATTTATITGGGAGGSGKDTTAATTTTTNKLRQLLLLVQQQMPFALWSFPVHHISQSHHQSQSQHKPSRQQKQHQHHSQVAPTSHHQSSSSTPPTPSTSSSPPSSSSSSSSSAMAAIVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .* : :* **. *: : * ::* :.*: ..:* :**: :: . * *:*:::*.****:: **:::*::::**:*** *:****:*.:**.*:: :.::*.* **********:::* .** :* * : *. *::.:. :: **:.:**** ** *.*: * : * * * . * :*. : :. .** .*.. ** *. .:.**** ****:.: :*: *:***::*:*. * :** *:* ***** *. ", "identical_positions": 103, "similar_positions": 96, "identity": "20.89%" }, { "cls_id": "homologset.agr.FB:FBgn0011822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7R7-1", "uniprot_id": "PEPC_MOUSE", "id": "Q9D7R7-1", "name": "Gastricsin", "aln": "-----MK----WMVVALLCLPLLEAALIRVPLKKMKSIRETMKEQGVLKDFLKNHKYDPGQKYHFGKFGDYSVLYEPMA-YMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSEACTTHTRYNPSKSSTYYTQGQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQ--QGSNGGQIVFGGVDENLYTGELTWIPVTQELYWQITIDDFLIGNQASGWCSSSGCQGIVDTGTSLLVMPAQYLNELLQTIGAQEGEYGQYFVSCDSVSSLPTLTFVLNGVQFPLSPSSYIIQ----EEGSCMVGLESLSLNAESGQPLWILGDVFLRSYYAVFDMGNNRVGLAPSV---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04073-1", "uniprot_id": "PEPC_RAT", "id": "P04073-1", "name": "Gastricsin", "aln": "-----MK----WMVVALLCLPLLEASLLRVPLRKMKSIRETMKEQGVLKDFLKTHKYDPGQKYHFGNFGDYSVLYEPMA-YMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSEACTTHARFNPSKSSTYYTEGQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQ--QGSNGGQIVFGGVDKNLYTGEITWVPVTQELYWQITIDDFLIGDQASGWCSSQGCQGIVDTGTSLLVMPAQYLSELLQTIGAQEGEYGEYFVSCDSVSSLPTLSFVLNGVQFPLSPSSYIIQ----EDNFCMVGLESISLTSESGQPLWILGDVFLRSYYAIFDMGNNKVGLATSV---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20142-1", "uniprot_id": "PEPC_HUMAN", "id": "P20142-1", "name": "Gastricsin", "aln": "-----MK----WMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFG---DLSVTYEPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQ--QGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCS-EGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DJD8-1", "uniprot_id": "PEPA3_HUMAN", "id": "P0DJD8-1", "name": "Pepsin A-3", "aln": "-----MK----WLLLLGLVA-LSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD--DQS-GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEA--IACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTESGE-LWILGDVFIRQYFTVFDRANNQVGLAPVA---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DJD7-1", "uniprot_id": "PEPA4_HUMAN", "id": "P0DJD7-1", "name": "Pepsin A-4", "aln": "-----MK----WLLLLGLVA-LSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD--DQS-GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEA--IACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTESGE-LWILGDVFIRQYFTVFDRANNQVGLAPVA---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DJD9-1", "uniprot_id": "PEPA5_HUMAN", "id": "P0DJD9-1", "name": "Pepsin A-5", "aln": "-----MK----WLLLLGLVA-LSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD--DKS-GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGET--IACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNVPTESGE-LWILGDVFIRQYFTVFDRANNQVGLAPVA---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70269-1", "uniprot_id": "CATE_MOUSE", "id": "P70269-1", "name": "Cathepsin E", "aln": "-----MKPLLVLLLLLLLDLAQAQGALHRVPLRRHQSLRKKLRAQGQLSEFWRSHNLDMTR--LSESCNVYSSVNEPLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYCTSPACKAHPVFHPSQSDTYTEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAAGGVTPVFDNMMAQNLVALPMFSVYLSSDP-QGGSGSELTFGGYDPSHFSGSLNWIPVTKQAYWQIALDGIQVGDTV--MFCSEGCQAIVDTGTSLITGPPDKIKQLQEAIGATP-IDGEYAVDCATLDTMPNVTFLINEVSYTLNPTDYILPDLVEGMQFCGSGFQGLDIPPPAGP-LWILGDVFIRQFYSVFDRGNNQVGLAPAVP--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W5G3-1", "uniprot_id": "Q9W5G3_DROME", "id": "Q9W5G3-1", "name": "", "aln": "MPRFQIKS-LVFLAGLIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQKYN--------RQYTANGYPMEHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKSSTYVANGTAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTDYIKVGSTS----ISTFAQAIADTGTSLIIAPQAQYDQISQLFNANS----EGLFECSSTS-YPDLIININGVDFKIPAKYYIIE----EEDFCSLAIQSINQD------FWIMGDVFLGRIYTEFDVGNQRLGFAPVNSAVGLRKAVLWRIFTLLLACGMWKLKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : : : ::*: : .::.. :* : : : : * : *:* *.**** *:* * **********.. * * ** * : ..*.** . .*: **:**::* :. * : . .: .* ** .* * : * ****:*:.:*.:: . .*..::.: :. : :*..:* : *. : :** * . ::*.: : *. **:: : : :.. .*.*.******: * : . .* : ..* : . * : : :* *.: : .. **: * ..: :**:****: :: :* .*:::*:*. ", "identical_positions": 89, "similar_positions": 120, "identity": "20.46%" }, { "cls_id": "homologset.agr.FB:FBgn0011824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CY66-1", "uniprot_id": "GAR1_MOUSE", "id": "Q9CY66-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGSFRGGGGGGGGSFRGGGRGGFGRG-GGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGGGGG---RGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGG-FRGGRGGGG---FRGRGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYA1-1", "uniprot_id": "GAR1_RAT", "id": "Q6AYA1-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGGGSNNHFRGG---------GGGGGGGGNFRGGGRGGFGRG-GGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGGGGGGGGRGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGG-FRGGRGGGGG--FRGRGH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY12-1", "uniprot_id": "GAR1_HUMAN", "id": "Q9NY12-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGGRGGFNRGGGGGGFNRGG-SSNHFRGG----------GGGGGGGNFRGGGRGGFGRG-GGRGGFNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRP-----PGEKGPP------RGGG------RGGRGG----GRG--GGGRG-----GGRG-GGFRGGRG-----GGGGGFRGGR-GGG---FRGRGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVE0-1", "uniprot_id": "GAR1_DANRE", "id": "Q7ZVE0-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MSF---RGGG------GGRGGGFNRGGGGG---RGG---------GFGGGRGGGFGGGRGGGFGGGRGGRGGFNRNQDYGPPEYVVALGEFMHPCEDEIVCKCVTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSDNMKASSFKKLQKFYIDPMKLLPLQRFLPRP-----PGEKGPP------RGGRGGGGG-RGGRGGGFRGGRGANGGGRGGF---GGRG-GGF-GGRG-----GGGGGFRGGRGGGGGRGFRGGR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVQ0-1", "uniprot_id": "GAR1_DROME", "id": "Q7KVQ0-1", "name": "H/ACA ribonucleoprotein complex subunit 1", "aln": "MGFGKPRGGG------GGGGRGFGGGGGGGGRGFGG----------GGGGRGGGGGRGGGGGFGRGGGGRGGGRGAFDTGPPERVIPLGNYVYSCQNDLVCKVDIQD--VPYFNAPIFLENKEQVGKIDEIFGTVRDYSVSIKLSDNVYANSFKPNQKLFIDPGKLLPIARFLPKP-----PQPKGAKKAFTNNRGGGGGGGG-FGGRGG----GRG--GGGRGGG---GGRGGGGFRGGAGRNGGGGGGGGFNRGRGGGGG-GGGGRGRW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28007-1", "uniprot_id": "GAR1_YEAST", "id": "P28007-1", "name": "H/ACA ribonucleoprotein complex subunit GAR1", "aln": "MSF---RGGN-----------------------RGG-------------------RGGFRGGFRGG---RTGSARSFQQGPPDTVLEMGAFLHPCEGDIVCRSINTK--IPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDGVQATSFKEGDKFYIAADKLLPIERFLPKPKVVGPPKPKNKKK----RSGAPGGRGGASMGRGG----SRGGFRGGRGGSSFRGGRGGSSFRGGSR-------GGSFRGGSRGGSRGGFRGGRR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* ***. ** * *** * * * : ***: *: :* :::.*:.::**: . :******::**** *:**:***:* :.: .::* .:.: *.*** :*::* . ****: ****:* * *. *. **** .** **** **** ..* ** ** *. * **. * ", "identical_positions": 82, "similar_positions": 46, "identity": "30.26%" }, { "cls_id": "homologset.agr.FB:FBgn0011826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63328-1", "uniprot_id": "PP2BA_MOUSE", "id": "P63328-1", "name": "Protein phosphatase 3 catalytic subunit alpha", "aln": "-----------------------------------------------------MSEPKAIDPKLST--------------------TDRVVKAVPFPPSHRLTAKEVFDN-DGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQ------------------------EHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSE--EDGFDGATAAA-----------------------------RKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEA------DEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM--PSDANLNSINKALASETNGTDSNGSNSSNIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63329-1", "uniprot_id": "PP2BA_RAT", "id": "P63329-1", "name": "Protein phosphatase 3 catalytic subunit alpha", "aln": "-----------------------------------------------------MSEPKAIDPKLST--------------------TDRVVKAVPFPPSHRLTAKEVFDN-DGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQ------------------------EHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSE--EDGFDGATAAA-----------------------------RKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEA------DEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM--PSDANLNSINKALASETNGTDSNGSNSSNIQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08209-1", "uniprot_id": "PP2BA_HUMAN", "id": "Q08209-1", "name": "Protein phosphatase 3 catalytic subunit alpha", "aln": "-----------------------------------------------------MSEPKAIDPKLST--------------------TDRVVKAVPFPPSHRLTAKEVFDN-DGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQ------------------------EHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSE--EDGFDGATAAA-----------------------------RKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEA------DEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM--PSDANLNSINKALTSETNGTDSNGSNSSNIQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BEY4-1", "uniprot_id": "A0A8M3BEY4_DANRE", "id": "A0A8M3BEY4-1", "name": "Serine/threonine-protein phosphatase", "aln": "-----------------------------------------------------MRMSSADIMGLNP--------------------TDRVIKSVPFPLSHRLSMREVFDC-EGKPRVDLLKAHLTKEGRVEEPVALRIVNEGAAILRQEKTMLDIEAPVTVCGDIHGQFFDLMKLFEVGGSPATTRYLFLGDYVDRGYFSIECVLYLWSLKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSEQVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHTLDDIKRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKSQ------------------------DYFSHNTVRGCSYFYSYPAVCEFLQTNNLLSVIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMNDG-DEIFDANAAAA-----------------------------RKEVIRNKIRAIGKMAKMFSVLREESENVLTLKGLTPTGMLPSGVLSGGKQTLQSATIEAIEAVEEVKDGEAIRGFSPQHKITSFEEAKGLDRINERMPPRRDVV--NSVG--LSMGKMNMAESNGTDDN----SNIQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48453-1", "uniprot_id": "PP2BB_MOUSE", "id": "P48453-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform", "aln": "-----------------------------------------------------MAAPEPARAAPPPPPPPPPPL-----------GADRVVKAVPFPPTHRLTSEEVFDM-DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQ------------------------EHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEG-EDQFDVGSAAA-----------------------------RKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEA------EKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAV--QQDG-FNSLNTAHTTENHGTGNHSAQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20651-1", "uniprot_id": "PP2BB_RAT", "id": "P20651-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform", "aln": "-----------------------------------------------------MAAPEPARAAPPPPPPPPPPL-----------GADRVVKAVPFPPTHRLTSEEVFDM-DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQ------------------------EHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEG-EDQFDVGSAAA-----------------------------RKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEA------EKAIRGSSPPHRICSFEEAKGLDRINERMPPRKDAV--QQDG-FNSLNTAHTTENHGTGNHSAQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16298-1", "uniprot_id": "PP2BB_HUMAN", "id": "P16298-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform", "aln": "-----------------------------------------------------MAAPEPARAAPPPPPPPPPPP-----------GADRVVKAVPFPPTHRLTSEEVFDL-DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQ------------------------EHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEG-EDQFD-GSAAA-----------------------------RKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEA------EKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAV--QQDG-FNSLNTAHATENHGTGNHTAQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1V9-1", "uniprot_id": "A0A8M2B1V9_DANRE", "id": "A0A8M2B1V9-1", "name": "Serine/threonine-protein phosphatase", "aln": "-----------------------------------------------------MSGKDQNKQST----------------------TERLVKAVPYPPTTRLTMKELYE--DGKPKVELLKSHLVKEGRLEEDVALRIINDGANILRHEKCMLEVEAPITVCGDVHGQFFDLMKLFEVGGSPHNTRYLFLGDYVDRGYFSIECVLYLWALKINHPTTLFLLRGNHECRHLTEYFTFKQECKIKYTERVYDACMEAFDCLPLAALLNQQFLCVHGGLSPEVTCLDDIRKLDRFKEPPAFGPMCDLLWSDPGEDYGSEKTS------------------------EHFCHNSVRGCSYFYSYPAVCDFLTNNNLLSVIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMSEG-DDTCEGGTPAV-----------------------------RKEVIRNKIRAIGKMARVFSVLREENESVLQLKGLTPTGMLPLGVLSGGRQTLQSATVEAEEA-------RAIQGFNPQHKIQSFEEARGLDRINERMPPRRDTK--QPDGTANSINAANSPDKNGTNTQA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48455-1", "uniprot_id": "PP2BC_MOUSE", "id": "P48455-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform", "aln": "-----------------------------------------------------MSVRRPQ-FST----------------------TERVIKAVPFPPTRRLTLKEVFE--NGKPKMDLLKNHLVKEGRVEEEVALKIINDGAAILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAALLNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDPLEDYGSEKTL------------------------EHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDEEMNVTD-E----EGATTG-----------------------------RKEVIKNKIRAIGKMARVFTVLREESENVLTLKGLTPTGTLPLGVLSGGKQTIETAKQEAAEE------REAIRGFTIAHRIRSFEEARGLDRINERMPPRKEASYHHDAGRMHSHSHPPHPQASRRTDHGKKAL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48454-1", "uniprot_id": "PP2BC_HUMAN", "id": "P48454-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform", "aln": "-----------------------------------------------------MSGRRFH-LST----------------------TDRVIKAVPFPPTQRLTFKEVFE--NGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTL------------------------EHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDD-EA---EGSTTV-----------------------------RKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEA------REAIRGFSLQHKIRSFEEARGLDRINERMPPRKDS--IHAGGPMKSVTS-AHSHAAHRSDQGKKAHS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27889-1", "uniprot_id": "PP2B2_DROME", "id": "Q27889-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit 2", "aln": "--------MSSNNQSSSVAQAATSARTVSAGSAEATDANSTASNNNNNSSSTAAAGNNSDNSSPTTGTGTGASTGKLHGGHTAVNTKERVVDSVPFPPSHKLTLAEVFDQRTGKPNHELLKQHFILEGRIEEAPALKIIQDGAALLRQEKTMIDIEAPVTVCGDIHGQFYDLMKLFEVGGSPASTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNS------------------------DFYTHNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMTEESEEPLSDDEAAL-----------------------------RKEVIRNKIRAIGKMARVFSVLREESESVLQLKGLTPTGALPLGALSGGKQSLKN----------------AMQGFSPNHKITSFAEAKGLDAVNERMPPRRDQP------PTPSEDPNQHSQQGGKNGAGHG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23287-1", "uniprot_id": "PP2B1_YEAST", "id": "P23287-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit A1", "aln": "MSKDLN------SSRIKIIK-----PNDSYIKVDRKK---------------DLTKYELENGKVIS-------------------TKDRPIASVPAITGKIPSDEEVFDSKTGLPNHSFLREHFFHEGRLSKEQAIKILNMSTVALSKEPNLLKLKAPITICGDIHGQYYDLLKLFEVGGDPAEIDYLFLGDYVDRGAFSFECLIYLYSLKLNNLGRFWMLRGNHECKHLTSYFTFKNEMLHKYDMEVYDACCRSFNVLPLAALMNGQYFCVHGGISPELKSVEDVNKINRFREIPSRGLMCDLLWADPVENYDDARDG-----------------SEFDQSEDEFVPNSLRGCSFAFTFKASCKFLKANGLLSIIRAHEAQDAGYRMYKNNKVTGFPSLITMFSAPNYLDTYHNKAAVLKYEENVMNIRQFHMSPHPYWLPDFMDVFTWSLPFVGEKVTSMLVSILNICSEQELDPES-EPKAAEETVKARANATKETGTPSDEKASS----AILEDETRRKALRNKILAIAKVSRMFSVLREESEKVEYLKTMN-AGVLPRGALARG-----------------------TEGLN--ETLSTFEKARKEDLINEKLPPSLSEVEQEKIKYYEKILKGAEKKPQL------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14747-1", "uniprot_id": "PP2B2_YEAST", "id": "P14747-1", "name": "Serine/threonine-protein phosphatase 2B catalytic subunit A2", "aln": "MSSDAIRNTEQINAAIKIIENKTERPQSSTTPIDSKASTVAAANSTATETSRDLTQYTLDDGRVVS-------------------TNRRIMNKVPAITSHVPTDEELFQPN-GIPRHEFLRDHFKREGKLSAAQAARIVTLATELFSKEPNLISVPAPITVCGDIHGQYFDLLKLFEVGGDPATTSYLFLGDYVDRGSFSFECLIYLYSLKLNFNDHFWLLRGNHECKHLTSYFTFKNEMLHKYNLDIYEKCCESFNNLPLAALMNGQYLCVHGGISPELNSLQDINNLNRFREIPSHGLMCDLLWADPIEEYDEVLDKDLTEEDIVNSKTMVPHHGKMAPSRDMFVPNSVRGCSYAFTYRAACHFLQETGLLSIIRAHEAQDAGYRMYKNTKTLGFPSLLTLFSAPNYLDTYNNKAAILKYENNVMNIRQFNMTPHPYWLPDFMDVFTWSLPFVGEKVTEMLVAILNICTEDELENDTPVIEELVGTDKKLPQAGKSEATPQPATSASPKHASILDDEHRRKALRNKILAVAKVSRMYSVLREETNKVQFLKDHN-SGVLPRGALSNG-----------------------VKGLD--EALSTFERARKHDLINEKLPPSLDELKNENKKYYEKVWQKVHEHDAKNDSK--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** : *::: * *. ..*: *: **::. * :*: .: : :* ::.: **:*:***:***::**:*******.* *********** **:**::**: **: :::*******:***.*****:* ** :*: * :*: ******:* *::*****:***: ::*:..::** * *: * :**:**:** *::.. : : *::****: :.: * *.** ..***::*************::.:. *****:*:********.*:****:****:********: :*******:*****************.*** :*.**:::*: *:: ::*** *:.*:::::::**:*.:.* ** . :* ** *.*: * .* . : :* .*: * :**::** . . . ", "identical_positions": 214, "similar_positions": 132, "identity": "32.52%" }, { "cls_id": "homologset.agr.FB:FBgn0011828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWB6-1", "uniprot_id": "A0A0G2JWB6_RAT", "id": "A0A0G2JWB6-1", "name": "", "aln": "MAVR---PTRRCLLALVLCFAWWAMAVVASKQGAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKKIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPESFQHLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKTYAQSGNAQAAATCEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQEADEGVYQCMAKNVAGEAKTHEVTLRYLG---------------------------------SPARPTFVIQPQNTEVLVGES--VTLECSATGHPLPQITWTRGDRTPLPIDPRVNITPSGGLYIQNVAQSDSGEYTCFASNSVDSIHATAFIIVQALPQFTVTPQSRVVIEGQTVDFQCEAKGYPQPVIAWTKGGSQLSVDRRHLVLSSG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP-RVTPVFASIPSDMTVEVGTNVQLPCSS-QGEPEPAITWNKDGVQVTE----SGKFHISPEGFLTINDVGTADAGRYECVARNTIGYASVSMVLSVNVPDVSRNGDPYVATSIVEAIATVDRAINSTRTHLFDSR----PRSPNDLLALFRYPRDPYTVGQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLSLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSSVCSNDPPCFSVMIPPNDPRVRSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQR-SGKPLLPFATGPP-TECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRGYDPSVNAGIFNAFATAAFRFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYENPGVFSPAQLTQLKQTSLARILCDNSDNITRVQHDVFRVAEFPHGYSSCEDIPRMDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYEEDKP-TKRARWRKALSV-KHGKHHSNATSVTHEHLEGPATNDLKEFVLEMQKIIT--------------DLRKQINSLESRLSTTECVDDSGESHGSNTKWEKDTCTVCECKNGQVTCFVEACQPAACPQ---PVKVEGACCPVCLRN----TEEEKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UQ28-1", "uniprot_id": "PXDN_MOUSE", "id": "Q3UQ28-1", "name": "Peroxidasin homolog", "aln": "MAVR---PTRRCLLALLLCFAWWAMAVVASKQGAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRSLNTLLLNNNQIKKIPNGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPESFQHLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKTYAQSGNAQAAATCEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQEADEGVYQCMAKNVAGEAKTQEVTLRYLG---------------------------------SPARPTFVIQPQNTEVLVGES--VTLECSATGHPLPQITWTRGDRTPLPIDPRVNITPSGGLYIQNVAQSDSGEYTCFASNSVDSIHATAFIIVQALPQFTVTPQSRVVIEGQTVDFQCAAKGHPQPVIAWTKGGSQLSVDRRHLVLSSG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP-RVTPVFASIPSDMTVEVGTNVQLPCSS-QGEPEPAITWNKDGVQVTE----SGKFHISPEGFLTINDVGTADAGRYECVARNTIGYASVSMVLSVNVPDVSRNGDPYVATSIVEAIATVDRAINSTRTHLFDSR----PRSPNDLLALFRYPRDPYTVGQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLSLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSSVCSNDPPCFSVMIPPNDPRVRSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQR-SGKPLLPFATGPP-TECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRGYDPSVNAGIFNAFATAAFRFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYENPGVFSPAQLTQLKQTSLARILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYEDDKP-TKRARWRKALSV-KHGKHLSNATSATHEHLEGPATNDLKEFVLEMQKIIT--------------DLRKQINSLESRLSTTECVDDSGESHGGNTKWKKDPCTVCECKNGQITCFVEACQPAACPQ---PVKVEGACCPVCLKN----TAEEKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92626-1", "uniprot_id": "PXDN_HUMAN", "id": "Q92626-1", "name": "Peroxidasin homolog", "aln": "MAKRSRGPGRRCLLALVLFCAWGTLAVVAQKPGAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFG---------------------------------SPARPTFVIQPQNTEVLVGES--VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP-RVTPVFASIPSDTTVEVGANVQLPCSS-QGEPEPAITWNKDGVQVTE----SGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSR----PRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQR-SGKPLLPFATGPP-TECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYQEDKP-TKKTRPRKIPSVGRQGEHLSNSTSAFSTRSDASGTNDFREFVLEMQKTIT--------------DLRTQIKKLESRLSTTECVDAGGESHANNTKWKKDACTICECKDGQVTCFVEACPPATCAV---PVNIPGACCPVCLQK----RAEEKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1KZ92-1", "uniprot_id": "PXDNL_HUMAN", "id": "A1KZ92-1", "name": "Probable oxidoreductase PXDNL", "aln": "MEPR-----LFCWTTLFLLAGWC-------LPGLPCPSRCLCFKSTVRCMHLMLDHIPQVPQQTTVLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSS---------------------------------LPAKPSFVIQPQDTEVLIGTS--TTLECMATGHPHPLITWTRDN--GLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSG--TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKP-KALAVFTQLPQDTSVEVGKNINISCHA-QGEPQPIITWNKEGVQITE----SGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQAGDDFVESSILDAVQRVDSAINSTRRHLFSQK----PHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDLVSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLG-LPVGSRQPLPPPRLVATVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRG-THAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPP-TECARQEQES--PCFLAGDHRANEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDCCADCRSRGQFRAVTQESQKKRSAQYSYPVDKD-MELSHLR---SRQQDKIYVGEDARNVTVLAKTKFSQDFSTFAAEIQETIT--------------ALREQINKLEARLRQAGCTDVRGVPRKAEERWMKEDCTHCICESGQVTCVVEICPPAPCPS---PELVKGTCCPVCRDRGMPSDSPEKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZZ4-1", "uniprot_id": "PXDN_DROME", "id": "Q9VZZ4-1", "name": "Peroxidasin", "aln": "MRFM---LLMLQLLGLLLLLAGG-------VQSVYCPAGCTCLERTVRCIRAKLSAVPKLPQDTQTLDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRWHLDVQRQLVSISLTCAAPQMLQNQGFSSLGEHHFKCAKPQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIELKELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRNNVDLAPGDRYVRIAFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTG-EARQLARAAEIYERTLVNIRKHVQEGDNLTMKSEEYEFRDLLSREHLHLVAELSGCMEHREMPNCTDMCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHAIPSVSSESW-DGIDCKKSCEMAPPCYPIEVPPNDPRV-RNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFP-RQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIFDSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEELIGSFQKELKKLHKKLRKLEDSCNSADSEPVAQVVQLAAAPPQLVSKPKRSHCVDDKGTTRLNNEVWSPDVCTKCNCFHGQVNCLRERCGEVSCPPGVDPLTPPEACCPHCPMVK---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.* . . **: * *:. ****:: *. :* :. :* ******:*.*: .** * .*.**:**:*.: : .*::.* * ::** :*.: : *: : ** :::. *:: * . * .* :*:**:::**::::: . *..*:.:******.*:: *:* : * : .: .. : * *: ::.:..::: ..::* *:: ***.:*.:*: * ::*.. * *:*:* *::*.:.*.:: ::: ::: .*:*:*:.: :* *:***:*:* * ::: . * . *: * *. **:: * : * . *:* *:* * * * * .. * :: ....* : : * . * : * * *. .:::*:* * :: *:: .:*:.:.: ::. * *.* * *.* * * *. : . *.. * :. . .. * *.* * . * .* . :.*: : . :: *.: . .* .:::.* : * * *:*.::* : : *:::. * * : :. .* ***** :* :* * .. .::: ** :* :: :* :* ***.* **..: * . .:** *::* . ***.**:*:** *:::*:.* : ::. .:.:.**:* . * *:*:**** :* : **:: *** :**: ********:* ***:**** ** . *.:*: * * . : * .***:* : :*** *:*:*:** **:**** :: ::* : ** *.. * ***:.: *.* *: ..***. *.** .* .:** ****** *:***.*:*** : :: :*: : .***: *. * :***:: :* *: :*. .**::** *.**::.* :***:*:*****:*::* :*.**:*:*:* *:******::****: :*** ::*: * . : *:**:* :*..* * *****:*****::**:*:**: .: *.:.*: :***:*:* *: ***:**::**::.*..* : *. *..***::**. *::.*:* ** ********:* * :* ***: . **** .**... **:*::.*** . ::*:: . ::** : * ::** : **: **:*******::*******:* ****:**:.:.*:*** .*.: :* :** *:. .* .*.:* ::* :**:* . . * : . :** . . .* : : . * . .: ::: : :::: * .* :: : *.* * .: : * : ** * * **:.*. * * ..*. * :*** * ", "identical_positions": 479, "similar_positions": 474, "identity": "30.9%" }, { "cls_id": "homologset.agr.FB:FBgn0011829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9H8-1", "uniprot_id": "RET_RAT", "id": "G3V9H8-1", "name": "Proto-oncogene tyrosine-protein kinase receptor Ret", "aln": "MAKARSGAAGLGLKLFLLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAPGEVPSFRLGQYLYGVYRTRLHENDWIHIDSGTGLLYLNQSLDHSSWEQLSIRNGGFPLLTVFLQVFLGSTAQREGECHWPGCARVYFSFINDTFPNCSSFKARDLCTPETGVSFRIRENRPPGTFYQFRMLPVQFLCPNISVKYKLLEGDGLPFRCDPDCLEVSTRWALDRE-----LQEKYVLEAECAVAGPGANKEKVAVSFPVTVYDEDDSPPTFSGGVGTASAVVEFK--RKEGTVVATLQVFDADVVPASGELVRRYTSTLLSGDSWAQQTFRVEHT-------------PNETLVQSNNNSVRATMHNYKLVLNRSLSISESRVLQLVVLVNDSDFQGPGSG-VLFLHFNVSVLPVTLNLPMAYSFPVNRRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSTNCSALGVVTSTE------DTSGTLYVNDTEALRRPECTELQYTVVATDRQTRRQTQASLVVTVEG-----TYIAEEVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDALESRDINICPQDCLRG-PIVGGHERGE-RQGIKAGYGICNCFPDEKKCFCEPEDSQ----------------------------GPLCDELCRTVITAAVLFSFIISVLLSTFCIHRYHKHAHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKIPE-DPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTPSDSLLYDDGLSEEETPLVDCNSAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTRADG-----------TSTGFPRYANDS-------------VYANWMVSPSAAKLMDTFDS------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35546-1", "uniprot_id": "RET_MOUSE", "id": "P35546-1", "name": "Proto-oncogene tyrosine-protein kinase receptor Ret", "aln": "MAKATSGAAGLGLKLILLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAPGEVPSFRLGQHLYGVYRTRLHENDWIRINETTGLLYLNQSLDHSSWEQLSIRNGGFPLLTIFLQVFLGSTAQREGECHWPGCTRVYFSFINDTFPNCSSFKAQDLCIPETAVSFRVRENRPPGTFYHFHMLPVQFLCPNISVKYSLLGGDSLPFRCDPDCLEVSTRWALDRE-----LREKYVLEALCIVAGPGANKETVTLSFPVTVYDEDDSAPTFSGGVGTASAVVEFK--RKEGTVVATLQVFDADVVPASGELVRRYTNTLLSGDSWAQQTFRVEHS-------------PIETLVQVNNNSVRATMHNYKLILNRSLSISESRVLQLAVLVNDSDFQGPGAGGILVLHFNVSVLPVTLNLPRAYSFPVNKRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSINCTALGVVTSPE------DTSGTLFVNDTEALRRPECTKLQYTVVATDRQTRRQTQASLVVTVEG-----TSITEEVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDAVESRDANICPQDCLRA-DIVGGHERGE-RQGIKAGYGICNCFPDEKKCFCEPEDSQ----------------------------GPLCDALCRTIITAA-LFSLIISILLSIFCVCHHHKHGHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSTENQVPVDSFKIPE-DPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTRADG-----------TSTGFPRYANDS-------------VYANWMVSPSAAKLMDTFDS------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07949-1", "uniprot_id": "RET_HUMAN", "id": "P07949-1", "name": "Proto-oncogene tyrosine-protein kinase receptor Ret", "aln": "MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDRE-----QREKYELVAVCTVH-AGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFK--RKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHW-------------PNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAG-VLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAE------DTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEG-----SYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRG-SIVGGHEPGE-PRGIKAGYGTCNCFPEEEKCFCEPEDIQ----------------------------DPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILE-DPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADG-----------TNTGFPRYPNDS-------------VYANWMLSPSAAKLMDTFDS------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KT06-1", "uniprot_id": "Q7KT06_DROME", "id": "Q7KT06-1", "name": "", "aln": "---MESTTIVFVTLLTIITQRKHCAAVDVYFPTTSVKFNMPINEESESIFSKIPLAQFQVLRMEDNRLAS----DYLYSLEQNPLLRINSSSGEIYMRTDYRSP--------NSSATFLVTAFPRDQPDHELLNVSHLSLEVTPQPLEEYCSELEHICFWSSAQYTIAESHGPYRRKDFFEPVLIGALNSRAAKYLCPHVSLEYSLNAG-SSHFVLKQNRLYTRQTLDHDELNGLNAKAGQLQARITCTVKLSSRDQRKFSRILDIKLLDRNDNGPKLQESSSKFDFYLEQPYFQADEEAGKKVIYVDKDTLEANAHLVYAVHNDSHGLFRPDCHAYEADHTGRPHTIVSCQLRFSRNGVFRETPYCVSLEARDLTIVSRVDAMSATANVCYHINLSKLHESEQELPQALPLRARQHRIFESEEFNGDSAGRSLSPPTVDYDKDVSVYRSAASNFRVVQPDSFLDLMRLRSIRFDIVEDKLGAFGITSTSGIVFVKNPQVLEEAPETIYFLNVTWIDQQRLSHVRVINVHLVHGRPENTSCELKVKSRSQTCAQIKYQSQCVRYCGLATGGGSCQWRGSNSAMFGTRYGSCVPESRYCPDHVCDPLEELNPMACPQDCTPAGRIVGPHSSNENKRGIYSASGTCICE-DNGKCSCAPLDEEPKMKKPRKRKNETEAEPLLGVRRGTPPNQPLQDPMLLGVLNVAGFECDRSCMFFVITCPLLFVLLLLCLLIAQRKMLQRRLGKQSMTTSSKQALPESGGGDFALMPLQSGFRFESGDAKWEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADG----------VEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLLGNNAKYIDLETNAVSNPLYCGDDSALITTELGEPESLQHLWSPPKIAYDIHDQATSYDQSEEEMPVTSTAPPGYDLPRPLLDATANGQVLRYENDLRFPLNIRKSSCTPSYSNMTSEPPATTSLPHYSVPVKRGRSYLDMTNKSLIPDNLDSREFEKHLSKTISFRFSSLLNLSETKEVSPGWQAEDAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * :: ..:.:**. : .: ::: : : : : : .: . **.. * *.:* : *:. :* :*:. . . * . .:*. : : . : :. : . .. : .*: .:* :: * : :. ..::***::*: * * * . * : * . *. : * * .. :. . : :.: *.:*. *.: . .. . :* : : . .: .* *.: *...** . :::..:* . : .: . * :: :: . . : .. * : : : . : . : :: : . .:. : : : .* . .. * :. : *. .. :.:* . .*** ::*::.:.*... : *. *:* :.:. : *.* : : . . :** * : :* . **.: * *:** .:. : .:.:* *.:: *** ** :* : ***** . *** *. .* :** :. * * * :: ** * * * : ** * : :: .* : . .::: * . *:. :* * .: : *... ... .. ..*:: . *.******::* *...*******:*:*. * .: * .* *********:.:. * *****::*::*.**:**** ***:.. . ***:***:*****.:** ***: . :. ... . :.: :::*****.:** **:*:***********:*:*:*: *******:*****:*:*:*:*:.*:****** *** **:**::********* **::***..*****.*:.*:.*****:**:**:**** :* :: ** :**: ** * ::.::**:: : .*:** :.: *:.* .*. : * * : :. : *. : : . * : * **. * . * :. . ** ** *:* .*.*:. : :. ", "identical_positions": 287, "similar_positions": 358, "identity": "22.74%" }, { "cls_id": "homologset.agr.FB:FBgn0011832", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1R3UCJ8-1", "uniprot_id": "A0A1R3UCJ8_RAT", "id": "A0A1R3UCJ8-1", "name": "", "aln": "-------------------------------------------MLLLLTILQALAVAIVQ-----------------------------------SQGDD-KILGGYTCVQNSQPWQVALQAGPGRRFLCGGVLLSDQWVITAAHCARPL--------LHVALGKHNLR-RWEATQQVLRVVRQVPHPQYR----PQAHD--------NDLMLLKLQRKVRLGRAVRTIPVAR--SCASPGTPCRVSGWGTTASPIV----RYPTALQCVNVNIMPEQVCHRAYP--------GTITSGMVCAGVPEGGKDSCQGDSGGPLVCQGQ----LQGLVSWGMERCAMPGYPGVYTNLCNYHSWIQRTMQSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0G3-1", "uniprot_id": "KLK14_HUMAN", "id": "Q9P0G3-1", "name": "Kallikrein-14", "aln": "-------------------------------------------MFLLLTALQVLAIAMTQ-----------------------------------SQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPI--------LQVALGKHNLR-RWEATQQVLRVVRQVTHPNYN----SRTHD--------NDLMLLQLQQPARIGRAVRPIEVTQ--ACASPGTSCRVSGWGTISSPIA----RYPASLQCVNINISPDEVCQKAYP--------RTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQ----LQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKR3-1", "uniprot_id": "KLK13_HUMAN", "id": "Q9UKR3-1", "name": "Kallikrein-13", "aln": "-------------------------------------------MWPLALVIASLTLALSGGV------------------------SQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQG--RLLCGGVLVHPKWVLTAAHCLKEG--------LKVYLGKHALG-RVEAGEQVREVVHSIPHPEYRRSPTHLNHD--------HDIMLLELQSPVQLTGYIQTLPLSHN-NRLTPGTTCRVSGWGTTTSPQV----NYPKTLQCANIQLRSDEECRQVYP--------GKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRT----LYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60259-1", "uniprot_id": "KLK8_HUMAN", "id": "O60259-1", "name": "Kallikrein-8", "aln": "------------------------------------MGRPRPRAAKTWMFLLLLGGAWAG----------------------------------HSRAQEDKVLGGHECQPHSQPWQAALFQGQ--QLLCGGVLVGGNWVLTAAHCKKPK--------YTVRLGDHSLQ-NKDGPEQEIPVVQSIPHPCYN-SSDVEDHN--------HDLMLLQLRDQASLGSKVKPISLAD--HCTQPGQKCTVSGWGTVTSPRE----NFPDTLNCAEVKIFPQKKCEDAYP--------GQITDGMVCAGSSKG-ADTCQGDSGGPLVCDGA----LQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M1-1", "uniprot_id": "KLK4_MOUSE", "id": "Q9Z0M1-1", "name": "Kallikrein-4", "aln": "----------------------------------MMVTARTPWGWFLGCLILEVTG-------------------------------------ASASSVSSRIIQGQDCSPHSQPWQAALFS-ED-GFFCSGVLVHPQWVLSAAHCLQES--------YIVGLGLHNLKGSQEPGSRMLEAHLSIQHPNFN----DPSFA--------NDLMLIKLNESVIESNTIRSIPVAT--QCPTPGDTCLVSGWGQLKNGK------LPSLLQCVNLSVASEETCRLLYD--------PVYHLSMFCAGGGQDQKDSCNGDSGGPIVCNRS----LQGLVSMGQGKCGQPGIPSVYTNLCKFTNWIQTIIQTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZRA7-1", "uniprot_id": "D3ZRA7_RAT", "id": "D3ZRA7-1", "name": "", "aln": "-----------------------------------MARAGHPWKWAMATLIATLVLGVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALLLGPN-KLYCGAVLINPQWLLTAAHCRKPV--------FRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYS----HPGHS--------NDLMLIKMNRKIRASHSVKPVEITS--DCPKEGTRCMVSGWGTTSSSHN----NFPKVLQCLDITVLSEERCKNSYP--------GQIDKTMFCAG-DEAGRDSCQGDSGGPVICNGK----LQGLVSWGDFPCAQPNRPGVYTNLCEFVPWIKDTIHSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07647-1", "uniprot_id": "KLK9_RAT", "id": "P07647-1", "name": "Submandibular glandular kallikrein-9", "aln": "-------------------------------------------MWFLILFLALSLGQID----------------------------------AAPPGQS-RVVGGYNCETNSQPWQVAVIG----TTFCGGVLIDPSWVITAAHCYSKN--------YRVLLGRNNLV-KDEPFAQRRLVSQSFQHPDYI-PVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPT--EEPKVGSICLASGWGMTNPSE----MKLSHDLQCVNIHLLSNEKCIETYK--------NIETDVTLCAGEMDGGKDTCTGDSGGPLICDGV----LQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AMU8-1", "uniprot_id": "A0A8I6AMU8_RAT", "id": "A0A8I6AMU8-1", "name": "tissue kallikrein", "aln": "-------------------------------------------NFFLYFFLDQVIIEQN----------------------------------AAPPGQS-RVVGGYKCEKNSQPWQVAVIS----RSLCGGVLIDPSWVITAAHCYSNY--------YHVLLGRNNLS-EDEPFAQYRFVSQSFPHPDYN-PFFMRNHTRQPGDDYSNDLMLLHLSKPADITDGVKVIDLPT--EEPKVGSTCLASGWGSTKPLDYRMWLGSAHDPLCVNIHLLSNEKCIEAYN--------EKVTDLMLCAGDLEGGKDTCKGDSGGPLICDGV----LQGITSWGSDPCAEPNMPAIYTKLIKFTSWIKEVMKENS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07478-1", "uniprot_id": "TRY2_HUMAN", "id": "P07478-1", "name": "Trypsin-2", "aln": "----------------------------------------------MNLLLILTFVAAA---------------------------------VAAPFDDDDKIVGGYICEENSVPYQVSLNSG---YHFCGGSLISEQWVVSAGHCYKSR--------IQVRLGEHNIE-VLEGNEQFINAAKIIRHPKYN-SRTLD-----------NDILLIKLSSPAVINSRVSAISLPT--APPAAGTESLISGWGNTLSSG----ADYPDELQCLDAPVLSQAECEASYP--------GKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGE----LQGIVSWGYG-CAQKNRPGVYTKVYNYVDWIKDTIAANS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NHM4-1", "uniprot_id": "TRY6_HUMAN", "id": "Q8NHM4-1", "name": "Putative trypsin-6", "aln": "----------------------------------------------MNPLLILAFVGAA---------------------------------VAVPFDDDDKIVGGYTCEENSVPYQVSLNSG---SHFCGGSLISEQWVVSAGHCYKPH--------IQVRLGEHNIE-VLEGNEQFINAAKIIRHPKYN-RIILN-----------NDIMLIKLSTPAVINAHVSTISLPT--APPAAGTECLISGWGNTLSSG----ADYPDELQCLDAPVLTQAKCKASYP--------LKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQ----LQGIVSWGYG-CAQKRRPGVYTKVYNYVDWIKDTIAANS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35030-1", "uniprot_id": "TRY3_HUMAN", "id": "P35030-1", "name": "Trypsin-3", "aln": "MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAARDADG----------------------CEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSG---SHFCGGSLISEQWVVSAAHCYKTR--------IQVRLGEHNIK-VLEGNEQFINAAKIIRHPKYN-RDTLD-----------NDIMLIKLSSPAVINARVSTISLPT--TPPAAGTECLISGWGNTLSFG----ADYPDELKCLDAPVLTQAECKASYP--------GKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQ----LQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAANS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ97-1", "uniprot_id": "Q9VQ97_DROME", "id": "Q9VQ97-1", "name": "trypsin", "aln": "-------------------------------------------MLLHWLVLVASVTLIS------------------------------------AGSSPERIVGGHPVLISEVPWQAALMYS--EKYICGAVIYSDKIIITAAHCVERP--------FDTLYSVRVGSVWKNLGGQHARVAVIRKHEDYVSSTILFN-----------DIAVIRLVDTLIFNAEVRPIQLAD--SAPAAGTEASVSGWGEIGILWL-----QPTSLLKTSVKILDPNVCKRSY---------QYITKTMICAAALLK--DSCHGDSGGPLVSGGQ----LVGIVSYGIG-CANPFFPGVYANVAELKPWILNAIEQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q5K2P8-1", "uniprot_id": "POLS2_MOUSE", "id": "Q5K2P8-1", "name": "Polyserase-2", "aln": "---------------------------------------MSPHLFLPVVVLVVSPTPGAFQDSAVSPTQG-----------------EFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLHHGG--GHICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLGVHSQDGPLEG-AHMRSVATILVPDNYS----RVELG--------ADLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDP---LPVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFG-CGRRNRPGVFTAVAHYESWIREHVMGSEPGPAFPSQLQKPPSEPWEPREENCTFAQPECGKATRPGTWPWEAQVMVPGSTPCYGALVSDSWVLAPASCFLDSLHDFETWRVLLPSRPEEKRVVRLVAHENASRNFASDLALLQLRTRVNLTAAPSAVCLPHREHYFLPGSRCRLARWGHGEPAPRSSAQLEAQLLNSWWCHCLYGRQGESVPPPGDPPHLLCPAYQEEEEAGACWVDSGWSLLCREEGTWFLAGYRTLSNGCLRPRAFSPMQTHGLWISHVTQGAYLEDQLTWDWGPEGEETEKQTCPPHTEHGACGLRPQSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSSTVPYIDVYLGLAGVSSLPQGHQVSRSVVSIRLPRHSGLRPPLALLELNSRVEPSPSALPICLHPEGVPPGASCWVLGWKDPQNRVPVAAAVSILTPRLCHCLYQGALTPGTFCVFYTEEQEDRCEMTSAPPLLCQTEGGPWVLVGMAVRGSRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDPCPQDLAGSASSPKVAALPLLLALLIPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q571E5-1", "uniprot_id": "PRS53_MOUSE", "id": "Q571E5-1", "name": "Serine protease 53", "aln": "-----------------------------------MRQSWRPELLIVGAVVVIEGLQAAQR-------------------------------ACGQRGPGPPEPQEGNTLPGEWPWQASVRRQG--VHICSGSLVADTWVLTAAHCFEKMATAELSS-WSVVLGSLKQE-GQSPGAEEVGVAALQLPKAYN----HYSQG--------SDLALLQLTHPTVQTTLCLPQPTYH----FPFGASCWATGWDQNTSDVS-------RTLRNLRLRLISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSKCAQEDTPVLLTDMAVHSSWLQAHVHEAAFLVQAPGVVKMSDENSCVACGSLRSAG----PQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGRQTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGEHGWVLG-----LTQKAGINYPQTVPVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWISN---LDWQVYFAEEPEPEAETGSCLVNSSQPASC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:* :: *.. : :::*.** . . . : *: ::.: * . :**. : * * .* . ..* *****::. : *. * : : : *: : ", "identical_positions": 22, "similar_positions": 38, "identity": "2.38%" }, { "cls_id": "homologset.agr.FB:FBgn0011836", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LNY6-1", "uniprot_id": "F1LNY6_RAT", "id": "F1LNY6-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "--MPPTGLESSRMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYNDPTLEVCHSESKQRNLN--------YFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLK------------------------IHINFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTFHYVLAIPTAASNISLAIGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYHHWIKEELDKIVAYELKTGGVLLH------PIFGGGKEKDNPASHLH-----FSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVG-------------------------PLKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYELRYERDVVAQQESILALEKFPTPA------SRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMID-----ALANSVTPAVS--VNNEVRTLDNLN----PDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDASLFKSYAEYGHFVDIR--IAALEAVVDYTKVDRSYEE---LQWLLNMIQTDPVPYVRHKILNMLTKNPP-FTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAVD--LYFTLFGLSRPSCLPLPELGLVLN--LKEKKAVLNPTIIPEAGVGNQET-----------------------------------------ASNPGCHTQLAGFQNPFSSSQDEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPSSSRSSLMPQHALGCDITPTTKPQWSMELSRKGAGKE-QPLEMGVHPVAAPLSVFAKEALSSARHSEHHHHHHHEHKKKKKKHKHKHKHKHKHDGKDKDKDKE-----------------PFTFS-SPASGRSVRSPSLSD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C176-1", "uniprot_id": "TAF2_MOUSE", "id": "Q8C176-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "------------MNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYNDPTLEVCHSESKQRNLN--------YFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLK------------------------IHINFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTFHYMLTIPTAASNISLAIGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTTSYIHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQALAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYHHWIKEELDKIVAYELKTGGVLLH------PIFGGGKEKDNPASHLH-----FSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSISNVSGKDIQPLIKQWLDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVG-------------------------PLKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMEADSPLLWIRIDPDMSVLRKVEFEQADFMWQYELRYERDVVAQQESILALEKFPTPA------SRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMID-----ALANSVTPAVS--VNNEVRTLDNLN----PDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDASLFKSYAEYGHFVDIR--IAALEAVVDYTKVDRSYEE---LQWLLNMIQTDPVPYVRHKILNMLTKNPP-FTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAVD--LYFTLFGLSRPSCLPLPELGLVLN--LKEKKAVLNPTIIPEAGVGNQ-----------------------------------------------------------FSSSQDEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRP-------------------------------------------------------------------HHHHHHHEHKKKKKKHKHKHKHKHKHD--SKDKDRE-----------------PFAFS-SPASGRSVRSPSLSD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1X5-1", "uniprot_id": "TAF2_HUMAN", "id": "Q6P1X5-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "--MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYNDPTLEVCHSESKQRNLN--------YFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLK------------------------IHINFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTFHYMLTIPTAASNISLAIGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLH------PIFGGGKEKDNPASHLH-----FSIKHPHTLSWEYYSMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVG-------------------------PLKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVVAQQESILALEKFPTPA------SRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMID-----ALANSVTPAVS--VNNEVRTLDNLN----PDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIR--IAALEAVVDYTKVDRSYEE---LQWLLNMIQNDPVPYVRHKILNMLTKNPP-FTKNMESPLCNEALVDQLWKLMNSGTSHDWRLRCGAVD--LYFTLFGLSRPSCLPLPELGLVLN--LKEKKAVLNPTIIPESVAGNQEA-----------------------------------------ANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHD--SKEKDKE-----------------PFTFS-SPASGRSIRSPSLSD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PW3-1", "uniprot_id": "TAF2_DANRE", "id": "Q32PW3-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "------------MNRKK-DKGFESPRPYKLTHQVVCINNVNFQRKSVIGYVELTIFPTVVNLNRIKLNSKQCRIYRVRVNDL-EAPFIYNDPTLEVCHHESKQRNLN--------YFSSAYTAAVSAVDPDAGNGELSIKVPSELWKQGDEMKVMK------------------------VYIEFSLDQPKGGLHFVVP--DVEGNMAERAAHVFSFGNQNSSRFWFPCVDSYSELCTWKLEFTVDASMVAVSC----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTYHYMLPIPTAAPNISMAVGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTMSYLHEIFEFYEEILTCRYPYSCFKTVFVDEAYVQVSSYASMSIFSTNLLHSGLIIDQTPMTRSFLAQALAQQFFGCFISRMSWADEWVLKGISGYIYGLYLKKTFGVNEYRHWIKEELDKIVEYELKIGGVLLH------PTFSGGKEKDNPTPHLH-----FSIKHPHTLSWEYYKMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKYQSHMWSQMLVSTSGFLKSISNVSGKDIGPLIKQWVDQSGVVKFFGSFAFNRKRNVLELEIRQDYTSS-GTQKYVG-------------------------PIKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSILRKVEFEQADFMWQYQLRYERDVVAQEEAILALEKFPTPP------SRRALTDILEQDQCFYKVRMHACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKSCPNIVKTNNFISFQSYFLQKTIPVAMAQLRDVQNLCPREVLSFILDLIKYNDNRKNKFSDNYYRAELID-----ALTNSLTPAIS--INNEVRTVDSLN----ADVRLILEEITRFLNMEKLLPSYRNTITVSCLRAIRMLQKNGHIPSDPTLFKSYAEYGHFVDVR--IAALEAVIDYTRVDRSSSE---LQWLLDLVQNDPVHYVRHEILSMLAKNPP-FTKAADSSLCNEALVDQLWKLMNSGTCHDWRLRCDAVN--LYYTLFGLTRPSCLPLPELGLVLN--LKEKKAVLNPTIKSEQIPGLPEMTPSMTFINTLKEEHVVMDPALSGVAMAPLSLKRKAETPVGSAPEPGQVLQEEPSAKITLKSREEEDIDMDTVHDSQAFIYHHLNMLERPSTPGKEPSSVEQAILS---------------------------------------MPGTPMPTLSKESTSSKHGEHHHHHHHHHEHKKKKKKHKHKHKHKHKHE--SKDKDRD-----------------SHAFVNSPASGLSIRSPSLSD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24325-1", "uniprot_id": "TAF2_DROME", "id": "Q24325-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "-------------METQPEVPEVPLRPFKLAHQVVSLTGISFERRSIIGVVELTIVPNSENLRLIRLNAKQLRIYSVVLNDVCQADFTYFDPFQNICYKEHKSRALE--------VYSKHHLTAAQYTDPDVNNGELLIQVPPEGYSMIQEGQGLR------------------------IRIEFSLENPKCGVHFVIPPASTDEETQMNSSHMFTNCYENSSRLWFPCVDSFADPCTWRLEFTVDKNMTAVSC----------------------------------------------------------------------------------------------------GELLEVIMTPDLRKKTFHYSVSTPVCAPNIALAVGQFEIYVDPHMH------------------------------------EVTHFCLPGLLP---LLKNTVRYLHEAFEFYEETLSTRYPFSCYKQVFVDELDTDISAYATMSIASVNLLHSIAIIDQTYISRTFMSRAVAEQFFGCFITSHHWSDTWLAKGIAEYLCGLYSRKCFGNNEYRAWVQSELARVVRYEEQYGGIILDCSQPPAPLPVSGTNQSAASSKQQEIVHYFPIKSLHTVSPKYVEAMRRKAHFVIRMLENRIGQELLIQVFNKQLALASSAATTKIGAGLWSQLLISTNIFIKAIFTVTGKDMSVFMDQWVRTGGHAKFSLTSVFNRKRNTIELEIRQDYVNQRGIRKYNG-------------------------PLMVQLQELDGT-FKHTLQIESTLVKSDITCHSKSRRNKKK-------------------------------------KIPLCTGEEVDMDLSAMD-DSPVLWIRLDPEMILLRDLIIEQPDFQWQYQLRHERDVTAQFQAIQALQKYPTNA------TRLALTDTIESERCFYQVRCEAAHSLTKVANQMVASWSGPPAMLNIFRKFFGSFSAPHIIKLNNFSNFQLYFLQKAIPVAMAGLRTSHGICPPEVMRFLFDLFKYNENSRNHYTDAYYRAALVE-----ALGETLTPVVSVAIHGTQITTDSLS----TDAKLVLDEVTRLLNMEKHLPSYKYMVSVSCLKVIRKLQKFGHLPSLPHIYRSYAEYGIYLDLR--IAAMECLVDFVKVDGRSED---LEHLITLLETDPDPAARHALAQLLIDNPP-FTRESRSRLDKPNLVDRLWFSINR-LPYDTKLRCDIVD--LYYALYGTKRPNCLQAGENQSFYKDLMKDNNSSVGSVTGSFKKTSDSKS--------------------------------------HLPTPTNTLDNEPQERQKPAMVTIKRTATEAFEVGDEIIKLERSEEITVLDEPVNVQAYDSETKVNALQADEEARDTHQAAKRLKNEMYAEDDNSS----------TMLDVGDSTRYESSHEEGKLKSGDGGLKKKKKKEKKKHKHKHKHRHSKD-KDKDKDKERKDKDKRDPHISRLQARETATPDTLSSEDSSNSNSLPPMNLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23255-1", "uniprot_id": "TAF2_YEAST", "id": "P23255-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "MMSFSKNATPRAIVSESSTLHEMKFRNFRVAHEKISLD-IDLATHCITGSATIIIIPLIQNLEYVTFDCKEMTIKDVLVENRRCDQFIHDDPLQTNLNGLTSQNVLYSDNSIEQSHFLRSKFASLNEYPETDSKSQLTIKIPSSIKISLEDANALSNYTPITPSIKTTPGFQESVFTPITLQIEYEIRNPKSGIKFDTV---YADKPWLWNVYTSNGEICSSASYWVPCVDLLDEKSTWELEFSVPRLVKNIGTSKLIGQNGEESEKEKEDTPEHDEEEEGKPARVIKDEDKDSNLKNDEEGKNSKSKDAQDNDEEEEEGESDEEEEEGEEERRNIEESNNPSLRDVIVCCSEYSNIKELPHPIDLTKKKCIFQIINPVAPHHIGWAIGAFNSWSLPLISPPSVDAEDEVEEDKLRENVVDNVNDTMDDDIGSDIIPIQIFTLPTQETDELTVINSTVVCQKIIDFYSKEFGS-YPFTCYSMVFLPTAPSKHMDFAALGICNTRLLYPLEVIDKAFSTTNELAWALANQWSCVNITPLDMNDYWCCLGIAGYMVFQVTKKLMGNNTYKYQLKRNSEAIVEQDFEKP-----------PIGSTFTGSSRPISWSS----------------KDLSFIQLKAPMILHILDRRMTKTERSFGMSRVLPKIFLQAMS----GDLPNNSLTSSHFQHVCERVNKSKLENFFNEWVYGSGVPILRVTQRFNRKRMVIELGIRQVQDEELGHEKVVGEEGFFKSALDHLEHPDLNRTECFTGSMTIRIHEHDGTPYEHIVEIKDTFTKIDIQYNTKYRRLRKRGGGANDENGVENNNEEKPIVVDVNCLGNVYMSPEECSRFSLTEFNRTSESNELLKQNEAFEWIRIDSDLEWICQMHINQPDYMFSSQLRQDGDIEAQLEAIRYYEDVVVNGGVKSLVYSSILFRTAIDERYFFGIRLAACEALSKYVYDPDFTG-GVKHLIQIFQILFCLEDS-NIPKSNNFENPKLYFLQCNIPKYLAKVKNENGKCPKLVKQFLLDILVYNENGENKYSDDAYVRSLIENVVKVALNEYKDKAYMEKVKTQLLRYENLVNWLSSYESLIKTTIMYAKYKLHKVGAYDFTELTGMIMHTLTLGINNGDISRESFQNEFLMVLKIMLLEGGLKNKDALVLFTEILCFHEDSYIRDKSVDVLSECVNLVVMDGSLDTISDDIKSSVQSVHNEVKNIKSEDDIELFLSGHYVDDMKIKIEKIGRQNISGLIQICRDMFKGYSPLKILLWDVLNLPVLSLYQRKQIHDLVRVMYTLIN--------------------------------------SFVVRLETPRERRLVAKMNSNEEGKLDIVIKRESILKVHIKKEVTSTVEAPKKANKIKISLKGDKP-------------------------------------VRKVEKQIVKPKVTSKQRKVKSHVNRMGSLPLRFVKIQQQPRVMVHLSSVPYSQFVQIT-----------------KVTSRSFMVKIRTKNDAKN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::::*: :.: :.: :.: * . : *.* **. : ::.*: * * ::: * : ** ... * : :: . .:.:* *::*.. :: : : : *::.: :** *::* . : . .*: *.**** : .**.***:* : :. .:: * . *: **. : : *... :*. *:* *: * : : * ** . : :: :: ::**.: : **::*:. **: . :*::.* ...**:. :**:: : :: ::*:*: *: * * **: *: :* :* * *: :: : :* : : * . .. . . : :: ** :::::::.*: :.: *. : .: ::: * : *. ..: ::.:*: .* : : ***** .:** *:* . * .* * .: : ::* **: ::* ::*:.. * ** ::* ** :*: ::.* :... . . :. :... ***:*.:: : .: ::*.*: :. :** : *: ** ::* :. . * .:: *: :* *. .*:* . . : * : .:* :* . :* * *** . : **** :* :* :: :. ** * *::*:: **:* .*:::* * ::: ** : . :: :.* . *: : : : :* .. : * . * : ..: : :. : :.:: :..: .: : : ::. . . . : .: .: . : : * : :. * ::: :. * * . :: : : .. : :. : :: .. : * ::: : * . .: : . : .. : ", "identical_positions": 163, "similar_positions": 355, "identity": "10.57%" }, { "cls_id": "homologset.agr.FB:FBgn0011837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17431-1", "uniprot_id": "TISB_RAT", "id": "P17431-1", "name": "mRNA decay activator protein ZFP36L1", "aln": "MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAG----GCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSSKFHQNQLLSSLKG------------------EP----APTLSSRDSRFRDRSFSEGGER---LLPTQKQPGSG---QVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCP-YGPRCHFIHNAEERR-ALAGGR--DLSAD--------------RPRLQHSFSFAGFPS------AAATAAATGLLD---SPTSITPPP------------------------------------------ILS----ADDLLG------SPTLPDGTNNPFAFSSQELASLFAP--------------------SMGLPGGGSP-------------------------TTFLFRPMSESPHMFDSPPSPQDSLSDHEGYLSS--SSSSHSGSDSPTLDNS--RRLPIFSRLSISDD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23950-1", "uniprot_id": "TISB_MOUSE", "id": "P23950-1", "name": "mRNA decay activator protein ZFP36L1", "aln": "MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAG----GCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSSKFHQNQLLSSLKG------------------EP----APSLSSRDSRFRDRSFSEGGER---LLPTQKQPGSG---QVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCP-YGPRCHFIHNAEERR-ALAGGR--DLSAD--------------RPRLQHSFSFAGFPS------AAATAAATGLLD---SPTSITPPP------------------------------------------ILS----ADDLLG------SPTLPDGTNNPFAFSSQELASLFAP--------------------SMGLPGGGSP-------------------------TTFLFRPMSESPHMFDSPPSPQDSLSDHEGYLSS--SSSSHSGSDSPTLDNS--RRLPIFSRLSISDD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07352-1", "uniprot_id": "TISB_HUMAN", "id": "Q07352-1", "name": "mRNA decay activator protein ZFP36L1", "aln": "MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAG----GCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSSKFHQNQLLSSLKG------------------EP----APALSSRDSRFRDRSFSEGGER---LLPTQKQPGGG---QVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCP-YGPRCHFIHNAEERR-ALAGAR--DLSAD--------------RPRLQHSFSFAGFPS------AAATAAATGLLD---SPTSITPPP------------------------------------------ILS----ADDLLG------SPTLPDGTNNPFAFSSQELASLFAP--------------------SMGLPGGGSP-------------------------TTFLFRPMSESPHMFDSPPSPQDSLSDQEGYLSS--SSSSHSGSDSPTLDNS--RRLPIFSRLSISDD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47974-1", "uniprot_id": "TISD_HUMAN", "id": "P47974-1", "name": "mRNA decay activator protein ZFP36L2", "aln": "MSTTLLSA--FYDVDFLCKTEKSLANLNLNN-------MLDKKAVGTPVAAAPSSGFAPGFLRRHSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCP-YGPRCHFIHNADERRPAPSGGASGDLRAFGTRDALHLGFPREPRPKLHHSLSFSGFPSGHH--QPPGGLESPLLLD---SPTSRTPPPPSCSSASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSASCANNAFAFG-PELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAP-PAQPPAPPSATLPAGAAAPPSPPFSFQLPRRLSDSP-VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG--RRLPIFSRLSISDD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZHK9-1", "uniprot_id": "D3ZHK9_RAT", "id": "D3ZHK9-1", "name": "mRNA decay activator protein ZFP36", "aln": "MSTTLLSA--FYDIDFLCKTEKSLANLNLNN-------MLDKKAVGTPVAAAPSSSFTPGFLRRHSASNLHALAH--PSPGSCSPKFPGAPNGSSCGPAGAGGPSSYGQLKEPSGGSGTALVNKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCP-YGPRCHFIHNADERRPAPSGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHH--QPPGGLESPLLLD---SPTSRTPPPPSCSSASSCSSSASSCSSTSAASTPSGAPTCCASAAAAAAAALLYGPGGAEDLLTPGAPCATCSTTSCANNAFTFG-PELSSLITPLAIQTHNFAA-AAAAYYRSQQQG-LAGLAPAPAQPPAAP---------APPSPPFGFQLPRRLSESP-VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG--RRLPIFSRLSISDD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22893-1", "uniprot_id": "TTP_MOUSE", "id": "P22893-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLSAIYESLQSMSHDL--SSDHGGTESL-------GGLWNINS-DSIPSG---------------------------VTSRLTGRSTSLVEGR-----------------------SCGWVPPPPGFAPLAPRPGPELS----PSPTSPTAT---PTTSSRYKTELCRTYSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCP-YGSRCHFIHNPTEDLALPGQPH-----------------------VLRQSISFSGLPSGRRSSPPPPGFSGPSLSSCSFSPSSSPPPP-------------------------------------------------GDLPLSPSAFSAAPGTPVTRRDPNQACCPSCRRSTTPST------------------IWGPLGGLAR---------------------------------SPSAHSLGSDP---DDYASSGSSLGGSDSPVFEAGVFGPPQTPAPPRRLPIFNRISVSE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47973-1", "uniprot_id": "TTP_RAT", "id": "P47973-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLSAIYESLMSMSHDL--SPDHGGTESS-------GGLWNINSSDSIPSG---------------------------VTSRLTGRSTSLVEGR-----------------------SCSWVPPPPGFAPLAPRPGPELS----PSPTSPTAT---PTTSSRYKTELCRTYSESGRCRYGAKCQFAHGPGELRQANRHPKYKTELCHKFYLQGRCP-YGSRCHFIHNPTEDLALPGQPH-----------------------VLRQSISFSGLPSGRRTSPPPPGFSGPSLSSCSFSPSSSPPPP-------------------------------------------------GDLPLSPSAFSAAPGTPVSRRDPTPACCPSCRRSTTPST------------------IWGPLGGLAR---------------------------------SPSAHSLGSDP---DDYASSGSSLGGSDSPVFEAGVFGPPQPPAPPRRLPIFNRISVSE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26651-1", "uniprot_id": "TTP_HUMAN", "id": "P26651-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLTAIYESLLSLSPDVPVPSDHGGTESSPGWG--SSGPWSLSPSDSSPSG---------------------------VTSRLPGRSTSLVEGR-----------------------SCGWVPPPPGFAPLAPRLGPELS----PSPTSPTAT---STTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCP-YGSRCHFIHNPSEDLAAPGHPP-----------------------VLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPP-------------------------------------------------GDLPLSPSAFSAAPGTPLARRDPTPVCCPSCRR-ATPIS------------------VWGPLGGLVR---------------------------------TPSVQSLGSDP---DEYASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47976-1", "uniprot_id": "CTH1_YEAST", "id": "P47976-1", "name": "mRNA decay factor CTH1", "aln": "------------MMPNVAPNSYYLNIPNANS---------TSTTTSSIFSD---------------------------LNKEYESKIKEIEEYY-----------------------IKTLLNENTDNDDSSSSEGHNINETDILSEYSPRPSPWLPSKPNCYHPLGDFKDLIISDSRPTNTLPINNPFAGNNNISTLATTEKKRKKRSLEVEINPTYTTSAFSLPLTAENLQKLSQVD------------------------SQSTGLPYTLPIQKTTKLEPCRRAPLQLPQLVNKTLYKTELC-------------------------------------------------ESFTIKGYCKYGNKCQFAHGLNELKFKKKSNNYRTKPCIN------------------WSKLGYCPYG------------------------KRCCFKHGDDKDVEIYQNANDGRSKDTALTPLPTSLAPSNNDNITNLSKPRNLHTSVKALQRMTW-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47977-1", "uniprot_id": "CTH2_YEAST", "id": "P47977-1", "name": "mRNA decay factor CTH2", "aln": "---------MWAQLSYTRPESQKTDLTSLFS---------TDQEQNPLN------------------------------DYQYQINIRELEEYY-----------------------NKTILNE--DNIQETSS--------EISSAVSFSP----PKNTNAIQPG------LLYDP------QLMNPFLPSAHLNSTAPTTFKKK---LEVQINPDYVPKSSQLPLTSQNLQQLSQQK------------------------PKND---ASFSSEKESSAQPKVKSQVQETP---KQLYKTELC-------------------------------------------------ESFTLKGSCPYGSKCQFAHGLGELKVKKSCKNFRTKPCVN------------------WEKLGYCPYG------------------------RRCCFKHGDDNDIAVYVKA--GTYCNVSSTSKQSDEKRSNG---RGSAKKKNLNVKVKALQRMTW-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47980-1", "uniprot_id": "TIS11_DROME", "id": "P47980-1", "name": "Protein TIS11", "aln": "MSADILQKSREQDDSHYFERGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHG-------ANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQ--------------------HQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCP-YGPRCHFVHNADEARAQQAAQAAKSSTQSQSQS--QQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSMSTG-----------------------------------SDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHG-----------------------PATPPESPNVPISPVHTPPPYDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNLGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . ... :. : : . : * * . . : . : . . . . . . : . . . . : :.*:: ", "identical_positions": 3, "similar_positions": 34, "identity": "0.57%" }, { "cls_id": "homologset.agr.FB:FBgn0012034", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXG4-1", "uniprot_id": "ACSA_MOUSE", "id": "Q9QXG4-1", "name": "Acetyl-coenzyme A synthetase, cytoplasmic", "aln": "--------------MGLPEERRKSGSGSRAREETGAEGRVRGWSPPPE--------------------------VRRSAHVPSLQRYRELHRRSVEEPREFWGNIAKEFYWKTAC-PGPFLQYNFDVTKGKIFTEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTK-ITYRELLVQVCQFSNVLR-KQGIQKGDRVAIYMPMILELVVAMLACARLGALHSIVFAGFSAESLCERILDSSCCLLITTDAFYRGEKLVNLKELADESLEKCREK-GFPVRCCIVVKHLGRAELGMNDSPSQSPPVKRPCPDVQ-------------ICWNEGVDLWWHELMQQAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTIGGYMLYVATTFKYVFDFHPEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDEGRLWSIVDKYKVTKFYTAPTAIRMLMKFGDDPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPG-ATPMKPGSASFPFFGVAPAILN-ESGEELEG-EAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPTLT------------EELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHD-LGDTSTVADPSVINHLFSHRCLTTQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJ11-1", "uniprot_id": "A0A8I6GJ11_RAT", "id": "A0A8I6GJ11-1", "name": "Propionate--CoA ligase", "aln": "MRPQRRPRCSELDVMGLPEERRKSGSGSRAREETGAEGRVRGWSPPPE--------------------------VRRSAHVPSLQRYRELHRRSVEEPREFWGNIAKEFYWKTPC-PGPFLQYNFDVTKGKIFTEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTK-ITYRELLVQVCQFSNVLR-KQGVQKGDRVAIYMPMILELVVAMLACARLGALHSIVFAGFSAESLCERILDSSCCLLITTDAFYRGEKLVNLKELADESLEKCREK-GFPVRCCIVVKHLGRAELGMNDSPSQSPPVKRPCPDVQGKLKEKSKCIRPQISWNEGVDLWWHELMQQAGDEFEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHPEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDEGRLWSIVDKYKVTKFYTAPTAIRMLMKFGDDPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPG-ATPMKPGSASFPFFGVAPAILN-ESGEELEG-EAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPTLT------------EELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHD-LGDTSTVADPSVINHLFSHRCLTTQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NR19-1", "uniprot_id": "ACSA_HUMAN", "id": "Q9NR19-1", "name": "Acetyl-coenzyme A synthetase, cytoplasmic", "aln": "--------------MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPE--------------------------VSRSAHVPSLQRYRELHRRSVEEPREFWGDIAKEFYWKTPC-PGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTQ-ITYHQLLVQVCQFSNVLR-KQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK-GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ-------------ISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPG-ATPMKPGSATFPFFGVAPAILN-ESGEELEG-EAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLT------------EELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHD-LGDMSTVADPSVISHLFSHRCLTIQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3X2-1", "uniprot_id": "A0A8M1P3X2_DANRE", "id": "A0A8M1P3X2-1", "name": "Acetyl-coenzyme A synthetase", "aln": "--------------MSPVSDSTNTALSSPKEPEE------KIYHPPDG--------------------------IFTDAHVPDFDAYLALYKKSIEEPEEFWGDVAQEFFWKKPP-SGQMLQYNFDVTKGSVFIKFMDGAKTNICYNVLDRNVHERNLGDKVAYYWVGNSPDHHLT-ITYNQLLRNVCRCANALK-LLGVKKGDRVAIYLPMIPELVYTMLACARIGAVHSIVFAGFSSESLCERIMDAQCNILVTADGVYRGDKLINLKKIASEALDRCKESSASSVQKCVVVKHPAFITSSDASSSLQTP-------------------------WDELCDIWWDDLMDGVSDECEPEWMDSEDPLFILYTSGSTGKPKGVVHTVTGYMLYTSLTFKYVFDYHHDDVYWCTADIGWITGHSYITYGPLANGATSVLFEGVPVHPHVGRLWEIIEKYGVSKFYTAPTAIRLLMKYGKEPLQRYDLSSLRVLGTVGEPINPEAWLWYYDVVGQQRCPVIDTFWQTETGGHVLTPLPA-ATPLKPGSATCPFFGVQPAILN-EHGEELEG-EAEGYLVFRQPWPGIMRGVFGNQERFESTYFRKFPGFYVTGDGCRRDKDGYYWITGRIDDMLNVSGHLLSTAEVESALSEHPSVAEAAVVSCPHAVKGECLYCFITLKDQQEFNRTLM------------DELKRKVREKIGPIATPDFIQNAPGLPKTRSGKIMRRVLRQIARNEKE-LGDLSTLADPKVVEVLFSQRCEAAA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP61-1", "uniprot_id": "ACSA_DROME", "id": "Q9VP61-1", "name": "Acetyl-coenzyme A synthetase", "aln": "----------------MPAEKS-------------------IYDPNPA--------------------------ISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISKGPISIKWMEGASTNLCYNLLDRNVRN-GLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLK-DHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLKALCDTALEKVEEM-GHSVEKCIVVSHLKRVTPCQPDHVEEEIP------------------------WTDDRDYWWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPG-ATPMKPGSASFPFFGVKPTLLD-ECGIEIKG-EGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPNENEVFDQKLI------------SDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVNDRN-VGDTSTLADEQIVEQLFANRPVEAK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52910-1", "uniprot_id": "ACS2_YEAST", "id": "P52910-1", "name": "Acetyl-coenzyme A synthetase 2", "aln": "--------------MTIKEHKVVYEAHNVKALKA--PQHFYNSQPGK-------------------------------GYVTDMQHYQEMYQQSINEPEKFFDKMAKEYLHWDAPYTKVQSGSLNNG-----DVAWFLNGKLNASYNCVDR--HAFANPDKPALIYEADDESDNKI-ITFGELLRKVSQIAGVLK-SWGVKKGDTVAIYLPMIPEAVIAMLAVARIGAIHSVVFAGFSAGSLKDRVVDANSKVVITCDEGKRGGKTINTKKIVDEGLNGVDLV-----SRILVFQRTGTEGIPMKAG----------------------------------RDYWWHEEAAKQRTYLPPVSCDAEDPLFLLYTSGSTGSPKGVVHTTGGYLLGAALTTRYVFDIHPEDVLFTAGDVGWITGHTYALYGPLTLGTASIIFESTPAYPDYGRYWRIIQRHKATHFYVAPTALRLIKRVGEAEIAKYDTSSLRVLGSVGEPISPDLWEWYHEKVGNKNCVICDTMWQTESGSHLIAPLAG-AVPTKPGSATVPFFGINACIIDPVTGVELEGNDVEGVLAVKSPWPSMARSVWNHHDRYMDTYLKPYPGHYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTSEIEASISNHENVSEAAVVGIPDELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIGPFASPKTIILVRDLPRTRSGKIMRRVLRKVASNEAEQLGDLTTLANPEVVPAIISAVENQFFSQKKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q01574-1", "uniprot_id": "ACS1_YEAST", "id": "Q01574-1", "name": "Acetyl-coenzyme A synthetase 1", "aln": "-----------MSPSAVQSSKLEEQSSEIDKLKAKMSQSAATAQQKKEHEYEHLTSVKIVPQRPISDRLQPAIATHYSPHLDGLQDYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDR--HALKTPNKKAIIFEGDEPGQGYS-ITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPGV-----RHVLVYRKTNNPSVAFHAP----------------------------------RDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVLKNKSSWSTATDDELQDIK-----KHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGIVRHLIDSVKL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:: * :::.*:::* :*:. * :: :: .. * .** :** : :: * : .: .. :*: :** :*.: : .* *::*** *::*:**: * ::** :*:**:**:******. ** :*: * .. :::* * ** * : * : . .* :* : * * *:*****:******** **** *: **:* . * : .** : *: : :.*:******:* **** * ::::**. * .* .* * :::.: .::**.****:* : : *. : .:. .*: **:***** .: * ** :* :. : ** ****:*.*:::**.. ..* *****: ****: . ::: * *:: . ** *.. .**.: * :: :: *: **: :**.* ****. :* *** ** **:**::***** :**:*:*: : :. *:*.***. . :.*: : .:: : . .* :* ***:* *. * . .**:*********:**:: .: : :** :*::: :: :: ", "identical_positions": 204, "similar_positions": 190, "identity": "26.19%" }, { "cls_id": "homologset.agr.FB:FBgn0012036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P46367-1", "uniprot_id": "ALDH4_YEAST", "id": "P46367-1", "name": "Potassium-activated aldehyde dehydrogenase, mitochondrial", "aln": "MFSRSTLCLKTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNG-SWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSS-RGDVDLVINYLKSSAGFADKID-GRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAG-LKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASES-IKVG---DPFDESTFQGAQTSQMQLNKILKYVDIGKNEG--ATLITGGER-LGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40047-1", "uniprot_id": "ALDH5_YEAST", "id": "P40047-1", "name": "Aldehyde dehydrogenase 5, mitochondrial", "aln": "MLSR-TRAAAPNSRIFTRSLLRLYSQAPLRVPITLPNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFET--KWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCA-RGDVALVSKYLRSCGGWADKIY-GNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADT-VKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTES-LKVG---DPFDEEVFQGAQTSDKQLHKILDYVDVAKSEG--ARLVTGGAR-HGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIAIDKPIR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54115-1", "uniprot_id": "ALDH6_YEAST", "id": "P54115-1", "name": "Magnesium-activated aldehyde dehydrogenase, cytosolic", "aln": "-------------------MTKLHFDTAEPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDT-EWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALA-RGDVTIAINCLRDAAAYADKVN-GRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVG---NPFDKANFQGAITNRQQFDTIMNYIDIGKKEG--AKILTGGEK-VGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9CZS1-1", "uniprot_id": "AL1B1_MOUSE", "id": "Q9CZS1-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----MLTARLLLPRLLCLQGR-TTSYSTAAALPNPIPNPEICYNKLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYFAGWADKWH-GKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGESNLKRVTLELGGKSPSIVLADADMEHAVDQCHEALFFNMGQCCCAGSRTFVEESIYREFLERTVEKAKQ-RKVG---NPFELDTQQGPQVDKEQFERILGYIRLGQKEG--AKLLCGGER-LGERGFFIKPTVFGDVQDGMRIAKEEIFGPVQPLFKFKKIEEVIQRANNTRYGLAAAVFTRDLDKAIYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLRAYTEVKTVTIKVPEKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HF8-1", "uniprot_id": "AL1B1_RAT", "id": "Q66HF8-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----MLNARFLVPRLLCLQGR-TTSYSTAAALPNPIPNPEIRYNQLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVLDLDEVIKVYRYLAGWADKWH-GKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCCAGSRTFVEESIYHEFLERTVEKAKK-RKVG---NPFELDTQQGPQVDKEQFEKILGYIRLGQKEG--AKLLCGGER-FGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKKIEEVIQRANNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVSEKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30837-1", "uniprot_id": "AL1B1_HUMAN", "id": "P30837-1", "name": "Aldehyde dehydrogenase family 1 member B1, mitochondrial", "aln": "-----ML--RFLAPRLLSLQGR-TARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWH-GKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQ-RKVG---NPFELDTQQGPQVDKEQFERVLGYIQLGQKEG--AKLLCGGER-FGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47738-1", "uniprot_id": "ALDH2_MOUSE", "id": "P47738-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----MLRAALTTVRRGPRLSR-LLSAAATSAVPAPNHQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAARAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH-GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEGVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQENVYDEFVERSVARAKS-RVVG---NPFDSRTEQGPQVDETQFKKILGYIKSGQQEG--AKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANDSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11884-1", "uniprot_id": "ALDH2_RAT", "id": "P11884-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----MLRAALSTARRGPRLSR-LLSAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKEDVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH-GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKS-RVVG---NPFDSRTEQGPQVDETQFKKILGYIKSGQQEG--AKLLCGGGA-AADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05091-1", "uniprot_id": "ALDH2_HUMAN", "id": "P05091-1", "name": "Aldehyde dehydrogenase, mitochondrial", "aln": "-----MLRAA---ARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH-GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKS-RVVG---NPFDSKTEQGPQVDETQFKKILGYINTGKQEG--AKLLCGGGI-AADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLC5-1", "uniprot_id": "Q9VLC5_DROME", "id": "Q9VLC5-1", "name": "aldehyde dehydrogenase (NAD(+))", "aln": "-----MLRVLKTGALLRSQAKNFAAAVANYSSLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNH-GKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKK-RTVG---NPFDLNTEQGPQVNEEQMEKILGMIKTGKKQG--AKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54114-1", "uniprot_id": "ALDH3_YEAST", "id": "P54114-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 2", "aln": "-----------------------MPTLYTDIEIP-QLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDN--VWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47771-1", "uniprot_id": "ALDH2_YEAST", "id": "P47771-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 1", "aln": "-----------------------MPTLYTDIEIP-QLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDN--VWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :***.:: : . * . :*:. : : . . *:: *: .* ** * .. *. * .* . :* . ::::*::* **. *: : : .. .** * * : :: *.** .**:***:*: * *: **. **. ::* * *.*. *: : :.*:* **:*::.* * .* : . : *::***** * : :. :* :*** ****. ::: *:::. :: .:: * *: * :.** :::. :* :.: : *. :**: *. . * . : : .: : : . . *:*: **:* .* : : ::*:***: : :*.. :: : **.: :**.:.: * .:... . :.*****:* : **** ** *** . * : *:* : ", "identical_positions": 113, "similar_positions": 151, "identity": "21.2%" }, { "cls_id": "homologset.agr.FB:FBgn0012037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RB66-1", "uniprot_id": "M0RB66_RAT", "id": "M0RB66-1", "name": "Angiotensin-converting enzyme", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFPWAFLLVLLY---------------------------YGQPLPWPKTVGEPSLDEFY--------SEAQAKMFLQFYEQTARVVLNELMEATWNYVTNITKQNQENMLQKEVERSQFMLYFGTRARMFRIDHFQDLDVKRRLSKLRNIDKSALPVEDFQEFNRLLTYMKTAYGRAEVCLDEGP---CMPLEPDLEEIMATSRDQKELLWAWQGWRDAIGRQLRPVFEDYVHLSNKAAQYNGYKDMGALWRSKYESD----------TLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPNKPPEDITKIMKNQHWRPEKMFEEANLFFTSMGMLPAPPAFWMKSMMEKPVDGREVECHTSSWNFYRLNDFRVKKCTEVTIGDLLSIFHQMGHIQYYLQCQNLSIIYQEGASPAFEEAVGSTITLSAFSHKYLLTRGLLSQQHQ-DSEEEVNFLLSIALEKIAFIPFGYMIDLFRWKVFDGTIQKNAYNQEWWSLRLKYQGLCPPVPRSEDDFDPGAKFHIPANMPYIRYFLSLVLQFQLHEVLCRASGHVG------PLHRCDIYNSKVAGKILGDFLKVGSSRPWQEVLKEITGKPNISTKALLTYFKPLLNWLVTENVKQGD----------------------ILGWPDFSCSFEEKITK-------KMSFLG--MKIEPDQAYLGQWVLLSMSFIMLCLILALGLRLHYLERRSLDSDTVILSTPPYAYFLGI------------AMEPRQAARKQWLLLGLCFVLMLCCIGLLIKIFIHHTRKPPWMKAEWQS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D0G895-1", "uniprot_id": "ACE3_MOUSE", "id": "D0G895-1", "name": "Angiotensin-converting enzyme-like protein Ace3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLPWALLLVLLS---------------------------HRQLLPWLRTVGETSLNDFY--------SEAQAKLFLQFYEQTAQVVLNEFMEATWNYVTNITKQNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLRKLQNIDKSALPTEDLLEYNRLLTYMETAYNRAEVCLDEGP---CLTLEPDLQEIMATSRDQKELLWAWQGWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGALWRSKYESD----------TLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPTKAPEDITAIMKIQHWRPEKMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFNDFRVKKCTEVTLEDLLSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLLARGLLSQPHQ-DSEEEVNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKYQGLCPPVPRSDDDFDPGAKFHIPANVPYIRYFLGLILQFQLHEALCEASGHVG------PLHQCDNYNSKVAGKILGDLLKLGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGD----------------------TLGWPDFSCSFEEKITS-------KVSFLG--TDTEPEQAYLGQWVLLSMSFFMLVLILALGFRLHYLEKQLLDEDTMILKTLPYSYFLGI------------AMEPHQAARKQWLLLGLCCILMLCCIGLLIRIVTQNTENTPWMKNEGQS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47820-1", "uniprot_id": "ACE_RAT", "id": "P47820-1", "name": "Angiotensin-converting enzyme", "aln": "MGAASGQRGRWPLSPPLLMLSLLLLLLLPPSPAPALDPGLQPGNFSADEAGAQLFADSYNSSAEVVMFQSTAASWAHDTNITEENARLQEEAALINQEFAEVWGKKAKELYESIWQNFTDQKLRRIIGSVQTLGPANLPLTQRLQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTNILASSRNYAKVLFAWEGWHDAVGIPLRPLYQDFTALSNEAYRQDGFSDTGAYWRSWYESPSFEESLEHLYHQVEPLYLNLHAFVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQKGWNATHMFRVAEEFFTSLGLSPMPPEFWAESMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDRVANDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNYDWWYLRTKYQGICPPVARNETHFDAGAKFHIPSVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSTKAGAKLQQVLQAGCSRPWQEVLKDLVGSDALDASALMEYFQPVSQWLQEQNQRNGEVLGWPEYQWRPPLPDNYPEGIDLETDEAKANRFVEEYDRTAKVLWNEYAEANWHYNTNITIEGSKILLQKNKEVSNHTLKYGTWAKTFDVSNFQNSTIKRIIKKVQNVDRAVLPPNELEEYNQILLDMETTYSVANVCYTNGT---CLSLEPDLTNIMATSRKYEELLWVWKSWRDKVGRAILPFFPKYVDFSNKIAKLNGYSDAGDSWRSSYESD----------DLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPSIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTSVNMEELVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGS-GYEHDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYIRYFISFIIQFQFHEALCRAAGHTG------PLYKCDIYQSKEAGKLLADAMKLGYSKQWPEAMKIITGQPNMSASAIMNYFKPLTEWLVTENRRHGE----------------------TLGWPEYTWTPNTARAEGSLPESSRVNFLG--MYLEPQQARVGQWVLLFLGVALLVATVGLAHRLYNIHN------HHSLRRPHRGPQFGS------------EVELRHS---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09470-1", "uniprot_id": "ACE_MOUSE", "id": "P09470-1", "name": "Angiotensin-converting enzyme", "aln": "MGAASGQRGRWPLSPPLLMLSLLVLLLQP-SPAPALDPGLQPGNFSPDEAGAQLFAESYNSSAEVVMFQSTVASWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELYESIWQNFTDSKLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGWPENQWRPPLPDNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGT---CMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSLYESD----------NLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGS-GYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTG------PLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGE----------------------TLGWPEYNWAPNTARAEGSTAESNRVNFLG--LYLEPQQARVGQWVLLFLGVALLVATVGLAHRLYNIRN------HHSLRRPHRGPQFGS------------EVELRHS---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12821-1", "uniprot_id": "ACE_HUMAN", "id": "P12821-1", "name": "Angiotensin-converting enzyme", "aln": "MGAASGRRG------PGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGS---CLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETP----------SLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGG-SDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTG------PLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGE----------------------KLGWPQYNWTPNSARSEGPLPDSGRVSFLG--LDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIR-------HRSLHRHSHGPQFGS------------EVELRHS---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q10714-1", "uniprot_id": "ACE_DROME", "id": "Q10714-1", "name": "Angiotensin-converting enzyme", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLFLLALLA------------------------------TLAVTQALVK---------------EEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLDEYEDD----------TFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVR-DDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNV----------------------HIGWTTSNKCVSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8R0I0-1", "uniprot_id": "ACE2_MOUSE", "id": "Q8R0I0-1", "name": "Angiotensin-converting enzyme 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSSWLLLSLVAVTTAQS------------------------------------------------LTEENAKTFLNNFNQEAEDLSYQSSLASWNYNTNITEENAQKMSEAAAKWSAFYEEQSKTAQSFSLQEIQTPIIKRQLQALQQSGSSALSADKNKQLNTILNTMSTIYSTGKVCNPKNPQE-CLLLEPGLDEIMATSTDYNSRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARANNYNDYGDYWRGDYEAEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHAYVRRKLMDTY-PSYISPTGCLPAHLLGDMWGRFWTNLYPLTVPFAQKPNIDVTDAMMNQGWDAERIFQEAEKFFVSVGLPHMTQGFWANSMLTEPADGRKVVCHPTAWDLGHG-DFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYARQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSDFQEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFRGEIPKEQWMKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKYNG------SLHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVVGARNMDVKPLLNYFQPLFDWLKEQNRNSFVGWNTEWSPYADQSIKVRISLKSALGANAYEWTNNEMFLFRSSVAYAMRKYFSIIKNQTVPFLEEDVRVSDLKPRVSFYFFVTSPQNVSDVIPRSEVEDAIRMSRGRINDVFGLNDNSLEFLGIHPTLEPPYQPPVTIWLIIFGVVMALVVVGIIILIVTGIKGRKKKNETKREENPYDSMDIGKGESNAGFQNSDDAQTSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5EGZ1-1", "uniprot_id": "ACE2_RAT", "id": "Q5EGZ1-1", "name": "Angiotensin-converting enzyme 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSCWLLLSLVAVATAQS------------------------------------------------LIEEKAESFLNKFNQEAEDLSYQSSLASWNYNTNITEENAQKMNEAAAKWSAFYEEQSKIAQNFSLQEIQNATIKRQLKALQQSGSSALSPDKNKQLNTILNTMSTIYSTGKVCNSMNPQE-CFLLEPGLDEIMATSTDYNRRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARANNYEDYGDYWRGDYEAEGVEGYNYNRNQLIEDVENTFKEIKPLYEQLHAYVRTKLMEVY-PSYISPTGCLPAHLLGDMWGRFWTNLYPLTTPFLQKPNIDVTDAMVNQSWDAERIFKEAEKFFVSVGLPQMTPGFWTNSMLTEPGDDRKVVCHPTAWDLGHG-DFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYAKQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSNFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFQDKIPREQWTKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKHDG------PLHKCDISNSTEAGQKLLNMLSLGNSGPWTLALENVVGSRNMDVKPLLNYFQPLFVWLKEQNRNSTVGWSTDWSPYADQSIKVRISLKSALGKNAYEWTDNEMYLFRSSVAYAMREYFSREKNQTVPFGEADVWVSDLKPRVSFNFFVTSPKNVSDIIPRSEVEEAIRMSRGRINDIFGLNDNSLEFLGIYPTLKPPYEPPVTIWLIIFGVVMGTVVVGIVILIVTGIKGRKKKNETKREENPYDSMDIGKGESNAGFQNSDDAQTSF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : * :*. ::: :: * * * :*** : : : . : . .. : * :** : : . :.*. .. : * *.: : :* .. : *:* : ::::.* . : : *. : * : : ** : .: *: *.: . . * . ** : :::* : :::*** ::*.*** * * :. * :* ****:**.: *.:: :. *: . * : * * : . ::*: .: **.*:.: . ** :*:: :* *.*.: **.::*:: *.*:* ** *. ::. .*::***** : .. : **. .*.**:*. ::**. : *:* .** . * :* *: ** : :** : :: :** :* . : : : :*.:: : *: *: : : *. : :*:. . ::** : ***: : * : . .* .** * ** : :.:* * * .:: . * :. ..: **:** ** :* :* . ", "identical_positions": 127, "similar_positions": 187, "identity": "8.8%" }, { "cls_id": "homologset.agr.FB:FBgn0012051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78EJ9-1", "uniprot_id": "CAN8_RAT", "id": "Q78EJ9-1", "name": "Calpain-8", "aln": "----------------------------------MAALAAGVSKQRAVAEG-----------------------------LGSNQNAVKYLG--QDFETLRKQCLNSGVLFKDPEFPACPSALGYKDLGPGSPDTQGIVWKRPTELCPNPQFIVGGATRTDIRQGGLGDCWLLAAIASLTLNEKLLYRVLPRDQSFQKDYAGIFHFQFWQYGEWVEVVIDDRLPTKNGQLLFLHSEEGNEFWSALLEKAYAKLNGSYEALVGGSTIEGFEDFTGGISEFYDLKKPPENLYYIIQKALRKGSLLGCSIDVS------------------------------------------------TAAEAEATTRQKLVKGHAYSVTGVEEVNFHGRP----EKLIRLRNPWG-EVEWSGAWSDNAPEWNYIDPRRKEELDKK-AEDGEFWMSFSDFLKQYSRLEICNLSPDSLSSEEIH----KWNLVLFNGRWTRGSTAGGCLNYPGTYWTNPQFKIHLDEVDEDQEEGT--------------------SEPCCTVLLGLMQKNRRRQKRIGQGMLSIGYAVYQIP-KELESHTDAHLGRDFFLGRQPSTCSSTYMNLREVSSRVRLPPGQYLVVPSTFEPFKDGDFCLRVFSEKKAKALEIGDTVSGHPHE-----------------------------------------------PHPRDMDEEDEHVRSLFEEFVG------------KDSEISANQLKRVLNE----------VLSKR-TDMKFD-----------------------------------------------------------------GFNINTCREMISLLDSDGTGSLGPMEFKTLWLKIRTYLEIFQEMDHNHVGTIEAHEMRTALKKA--------GFTLNNQVQQTIAMRYACSKLGVDFNGFVACMIRLETLFKLFRLLDKDQNGIVQLSLAEWLCCVLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VA3-1", "uniprot_id": "CAN8_MOUSE", "id": "Q91VA3-1", "name": "Calpain-8", "aln": "----------------------------------MAALAAGISKQRAAAQG-----------------------------LGSNQNAVKYLG--QDFETLRKQCLNSGVLFKDPEFPACPSALGYRDLGPGSAETQGIIWKRPTELCSNPQFIVGGATRTDIRQGGLGDCWLLAAIASLTLNEKLLYRVVPRDQSFQKNYAGIFHFQFWQYGEWVEVVIDDRLPTKNGQLLFLHSEEGNEFWSALLEKAYAKLNGSYEALAGGSTIEGFEDFTGGISEFYDLRKPPGNLYYTIQKALRKGSLLGCSIDVS------------------------------------------------NAAEAEATTRQKLVKGHAYSVTGVEEVDFRGLP----EKLIRLRNPWG-EVEWTGAWSDSAPEWNYIDPQKKGELDKR-AEDGEFWMSFSDFLKQFSRLEICNLSPDSLSSEEIH----KWNLVLFNGRWTRGSTAGGCQNYPATYWTNPQFKIHLDEVDEDQEEGT--------------------SEPCCTVLLGLMQKNRRRQRRIGQGMLSIGYAVYQIP-KELENHTDEHLGRDFFQGRQPSTCSSTYMNLREVSSRVQLPPGQYLVVPSTFEPFKDGDFCLRVFSEKKAQALEIGDAVPGDPHE-----------------------------------------------PHPRDMDGEDEHFWSLSEEFAD------------KDSEISAHQLKRVLNG----------LLSKR-TDMKFD-----------------------------------------------------------------GFNINTCREMISLLDGDGTGSLRPVEFKTLWLKICKYLEIYQEMDHSRAGTIDAHEMRTALKKA--------GFTLNNQVQQTIATRYACSKLGVDFDGFVACMIRLEILFKLFRLLDKDQNGIVQLSLAEWLCRALV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHC0-1", "uniprot_id": "CAN8_HUMAN", "id": "A6NHC0-1", "name": "Calpain-8", "aln": "----------------------------------MAAQAAGVSRQRAATQG-----------------------------LGSNQNALKYLG--QDFKTLRQQCLDSGVLFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELCPSPQFIVGGATRTDICQGGLGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFHFQFWQYGEWVEVVIDDRLPTKNGQLLFLHSEQGNEFWSALLEKAYAKLNGCYEALAGGSTVEGFEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCSIDVS------------------------------------------------SAAEAEAITSQKLVKSHAYSVTGVEEVNFQGHP----EKLIRLRNPWG-EVEWSGAWSDDAPEWNHIDPRRKEELDKK-VEDGEFWMSLSDFVRQFSRLEICNLSPDSLSSEEVH----KWNLVLFNGHWTRGSTAGGCQNYPATYWTNPQFKIRLDEVDEDQEESI--------------------GEPCCTVLLGLMQKNRRWRKRIGQGMLSIGYAVYQVP-KELESHTDAHLGRDFFLAYQPSARTSTYVNLREVSGRARLPPGEYLVVPSTFEPFKDGEFCLRVFSEKKAQALEIGDVVAGNPYE-----------------------------------------------PHPSEVDQEDDQFRRLFEKLAG------------KDSEITANALKILLNE----------AFSKR-TDIKFD-----------------------------------------------------------------GFNINTCREMISLLDSNGTGTLGAVEFKTLWLKIQKYLEIYWETDYNHSGTIDAHEMRTALRKA--------GFTLNSQVQQTIALRYACSKLGINFDSFVACMIRLETLFKLFSLLDEDKDGMVQLSLAEWLCCVLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07009-1", "uniprot_id": "CAN2_RAT", "id": "Q07009-1", "name": "Calpain-2 catalytic subunit", "aln": "----------------------------------MAGIAMKLAKDREAAEG-----------------------------LGSHERAIKYLN--QDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDIT------------------------------------------------SAADSEAVTYQKLVKGHAYSVTGAEEVESSGSL----QKLIRIRNPWG-QVEWTGKWNDNCPSWNTVDPEVRANLTER-QEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYK----KWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDED----------------------GERGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVP-EELTGQTNIHLSKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEE-----------------------------------------------IEANEEDIGDG-FRRLFAQLAG------------EDAEISAFELQTILRR----------VLAKR-EDIKSD-----------------------------------------------------------------GFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA--------GFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08529-1", "uniprot_id": "CAN2_MOUSE", "id": "O08529-1", "name": "Calpain-2 catalytic subunit", "aln": "----------------------------------MAGIAIKLAKDREAAEG-----------------------------LGSHERAIKYLN--QDYETLRNECLEAGALFQDPSFPALPSSLGYKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPPDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDIT------------------------------------------------SAADSEAVTYQKLVKGHAYSVTGAEEVESSGSL----QKLIRIRNPWG-QVEWTGKWNDNCPSWNTVDPEVRANLTER-QEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYK----KWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEED----------------------GERGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVP-EELTGQTNIHLGKNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHKDGDFCIRVFSEKKADYQAVDDEIEANIEE-----------------------------------------------IDANEEDIDDG-FRRLFVQLAG------------EDAEISAFELQTILRR----------VLAKR-QDIKSD-----------------------------------------------------------------GFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA--------GFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIQLNLASWLSFSVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17655-1", "uniprot_id": "CAN2_HUMAN", "id": "P17655-1", "name": "Calpain-2 catalytic subunit", "aln": "----------------------------------MAGIAAKLAKDREAAEG-----------------------------LGSHDRAIKYLN--QDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDIT------------------------------------------------SAADSEAITFQKLVKGHAYSVTGAEEVESNGSL----QKLIRIRNPWG-EVEWTGRWNDNCPSWNTIDPEERERLTRR-HEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYK----KWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEED----------------------GESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVP-EELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEE-----------------------------------------------FDISEDDIDDG-FRRLFAQLAG------------EDAEISAFELQTILRR----------VLAKR-QDIKSD-----------------------------------------------------------------GFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEA--------GFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYR6-1", "uniprot_id": "A0A8M1NYR6_DANRE", "id": "A0A8M1NYR6-1", "name": "calpain-2", "aln": "----------------------------------MSNIAKVLSRRQDRGEG-----------------------------LGTNEKAIPYNK--QDYQSLKQECLAKRALFCDPTFPAESDSLGYNELGRYSFKTKGVQWKRPKELCSNPEFIMDGANRTDICQGALGDCWLLAAIASLTLDKEILERVVPSGQSFTEDYAGIFHFQFWQYGEWVDVVIDDRLPTRDGKLLFVHSAEGSEFWSALLEKAYAKVNGSYEALTGGSTTEGFEDFTGGITENYELSKAPPNLFKLVQKALALGSLLGCSIDIT------------------------------------------------NSYETEAVTSLKLVKGHAYSVTAAEEVHFRGSL----VQLVRIRNPWG-EVEWTGAWSDNSKEWDSVRPEEKAKLDYS-AEDGEFWMAYSDFIQQFSKLEICNLTPDTLSSEEVN----RWSYSQFEGNWRVGSTAGGCRNNPATFCSNPQFMIKLEEIDDDPHD----------------------GVNGCTFLVGLIQKDGRKDKRFGRDLNTIGFAIYKVP-DELKGRSNIHLGPDVLLRQRSVAGSNTFINLREVSERFKLPPGEYIIIPSTFEPHRKGSFILRVFAEKEADASQIGTEISADVKK-----------------------------------------------HFISEKD-IDPHFKRLFSQVAG------------SDSEVSVLELQQILNT----------VVSKRKSNVKTD-----------------------------------------------------------------GFSLETCRHIISLLDKDGSGKLGLLEFHTLWMKIQKYLEIFKHRDTDNSGTMSSLEMRDAVKEA--------GFQLNNDVLEVLIARYANQEYAIDFDSFVSCLIRLELLFKMFQLFDKKNTGKIELDILQWLCLALS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P97571-1", "uniprot_id": "CAN1_RAT", "id": "P97571-1", "name": "Calpain-1 catalytic subunit", "aln": "------------------------MAEELITPVYCTGVSAQVQKQRDKELG-----------------------------LGRHENAIKYLG--QDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINIS------------------------------------------------DIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQR----VNLIRMRNPWG-EVEWKGPWSDNSYEWNKVDPYEREQLRVK-MEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLR----NWNTTFYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDS--------------------RESGCSFLLALMQKHRRRERRFGRDMETIGFAVYQVP-RELAGQP-VHLKRDFFLANASRAQSEHFINLREVSNRIRLPPGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPD-----------------------------------------------EKVLSEEEIDDNFKTLFSKLAG------------DDMEISVKELQTILNR----------IISKH-KDLRTN-----------------------------------------------------------------GFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAA--------GFKLNKKLHELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKILDTDLDGVVTFDLFKWLQLTMFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35350-1", "uniprot_id": "CAN1_MOUSE", "id": "O35350-1", "name": "Calpain-1 catalytic subunit", "aln": "------------------------MTEELITPVYCTGVSAQVQKKRDKELG-----------------------------LGRHENAIKYLG--QDYETLRARCLQSGVLFQDEAFPPVSHSLGFKELGPHSSKTYGIKWKRPTELMSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQDGYAGIFHFQLWQFGEWVDVVIDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINIS------------------------------------------------DIRDLEAITFKNLVRGHAYSVTGAKQVTYQGQR----VNLIRMRNPWG-EVEWKGPWSDSSYEWNKVDPYEREQLRVK-MEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLR----NWNTTFYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDN--------------------RESGCSFLLALMQKHRRRERRFGRDMETIGFAVYQVP-RELAGQP-VHLKRDFFLANASRAQSEHFINLREVSNRIRLPPGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPD-----------------------------------------------EKVLSEEEIDDNFKTLFSKLAG------------DDMEISVKELQTILNR----------IISKH-KDLRTN-----------------------------------------------------------------GFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAA--------GFKLNKKLHELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKLLDTDLDGVVTFDLFKWLQLTMFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07384-1", "uniprot_id": "CAN1_HUMAN", "id": "P07384-1", "name": "Calpain-1 catalytic subunit", "aln": "------------------------MSEEIITPVYCTGVSAQVQKQRARELG-----------------------------LGRHENAIKYLG--QDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDIS------------------------------------------------SVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQV----VSLIRMRNPWG-EVEWTGAWSDSSSEWNNVDPYERDQLRVK-MEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTIR----KWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGD--------------------RESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVP-PELVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPD-----------------------------------------------EQVLSEEEIDENFKALFRQLAG------------EDMEISVKELRTILNR----------IISKH-KDLRTK-----------------------------------------------------------------GFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESA--------GFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U468-1", "uniprot_id": "A0AB32U468_DANRE", "id": "A0AB32U468-1", "name": "Calpain-1 catalytic subunit", "aln": "-------------------------------MFSYGGISAHISANRLKADG-----------------------------AGSFEQALHFQN--QDYEALRQECLEGGYLFEDPCFPAEPPSLGFKELAPHSSKTRDVEWMRPTELCDDPQFIVGGATRTDICQGALGDCWLLAAIGSLTLNERLLHRVVPHGQSFQDDYAGIFHFQFWQFGEWVDVVIDDRLPVKDGELMFVHSAEGNEFWSALVEKAYAKLNGSYEALSGGSTTEGFEDFTGGVSEMYELRKAPRDLYRIISKALDRGSLLGCSIDIT------------------------------------------------SAFDMESVTFKKLVKGHAYSVTALKQVEYRGRM----ERLIRIRNPWG-QVEWTGAWSDNSPEWDEIDPSEKDDLHLQ-MEDGEFWMSFGEFLRQFSRLEICNLTPDALSDDDMS----HWNTIKFHGAWRRGSTAGGCRNHPNTFWINPQYKITLLEEDD--DPED--------------------EEVACSFLVALMQKDRRRYRRHGQDMHTIGFAIYEVRSQWYTGCQNVHLKKDFFLSNSSAARSETFINLREVSTRLRLPPGEYIIVPSTFEPSKEADFVLRVFTEKQSETEELDDEISADLED-----------------------------------------------EEEITEDDIDDSFKSLFAQLAG------------EDMEISVHELKTILNR----------VVSKH-KDVKTD-----------------------------------------------------------------GFSMDSCRTMVNLLDKDGSARLGLVEFQILWNKIRKLLGIFREFDIDKSGTMSSYEMRLAVESA--------GFKLNNRLNQILVARYAENE-AIDFDNFVCCLIKLEAMFRSFQQLDREETGTAEMNLSEWLFMTMCG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BLC4-1", "uniprot_id": "A0A8M2BLC4_DANRE", "id": "A0A8M2BLC4-1", "name": "Calpain-1 catalytic subunit", "aln": "-------------------------------MFSIGGVSTRIYKERLQAEG-----------------------------MGANDLAIKFLN--QDYEELRRECVESGRLFEDPCFPAVPQSLGFKELAPNSSKTRGVKWIRPTELSENPQFIVGGATRTDICQGALGDCWLLAAIASLTLNDKLLHRVVPHGQSFTNEYAGIFHFQFWQFGEWVDIVIDDRLPVKDKELMFVHSAEGNEFWSALLEKAYAKLNGSYEALSGGSTTEGFEDFTGGVAEMYELRSAPKDLHRIIAKALERGSLLGCSIDIT------------------------------------------------SAFDMEAVTFKKLVKGHAYSVTALREVNFRGNR----ERLIRIRNPWG-QVEWTGAWSDNSSEWNGIDPSEREELNNH-MEDGEFWMSFQEFKRQFSRLEICNLTPDALSDDSQH----FWNTIQFNGTWRKGSTAGGCRNNPNTFWINPQYKITLLEEDD--DPED--------------------NEVACTFMVALMQKDRRRFRKQGQDMHTIGFALYEVP-DEFLGSQNVHLKKDFFLRHSSCARSETFINLREVSTRLRLPPGEYLIVPSTFEPGKEADFVLRVFTEKQSETQEMDDEISFNLED-----------------------------------------------EEAVSEENIDASFKKMFAQLSG------------EDMEISVHELRTILNR----------VMTKH-RDLKTD-----------------------------------------------------------------GFSLESCRCMINLMDKDGSARLGIVEFQILWNKIRKWLGVFRQFDLDKSGTMSSYEMRLAVESA--------GFKLNNKLHQILVARYSDGD-VIDFDNFVCCLVKLEAMFKSFKELEKEGSGVAELNISEWLYLTMCG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V8Q1-1", "uniprot_id": "CAN11_RAT", "id": "Q4V8Q1-1", "name": "Calpain 11", "aln": "MLN------------------------FSDISYAERGMVATINSNRLKDKG-----------------------------VGQYQNAYNYKN--QNFEDLRASCLKMGELFEDPFFPAEPQSIGFKELGPKSQEVHNVYWQRPKDIIHNPQFITNDFSPTDICQGILGDCWLLAAIGSLTTSPKLLFRVVPRSQSFKKNYAGIFHFQLWQFGHWLNVVVDDRLPTKNNKLVFVHASHRQEFWGALLEKAYAKLNGSYEALTGGSTMEGLEDFTGGMAQCIRLQNPPHNLLRLLRKALEKSSLMGCSIEVT------------------------------------------------NSDDVEKMAHNMLVKGHAYAITGLQDVYYRDKL----ETLIRIQNPWG-RIEWNGAWSDKAKEWEEVMPEVQMQLLHK-KEDGEFWMSYEDFMSNFTLLEICNLTPDALSSWDYKS---CWHTTFFEGSWRRGSTAGGCRNYPETFWSNPQFRISLPETDDPEDSSDK-------------------SEMVCTCLVALMQKNWRHARE-GPQLLTIGFVVFSVWYVQFQNLQDIHLKKDFFMKYRDHGFSEIFTNTREVNSHLRLPPGEYVIIPSTFEPHKDADFLLRVFTEKHSETWLLDEVNMLEQLQ-----------------------------------------------EETITDADLDQNSVELFETLAN------------RDSQVDMYDLQKLLNK----------MSSKV-KSFKSK-----------------------------------------------------------------GFSLDVCRRMVNLMDKDDSGKLGLHEFHILWKKIKKWMEIFKECDQDRSGNLNSYEMRLAIEKA--------GIRMNNRVTEVVVARYADANMIVDFDNFINCFLRLKAMFAFFLSMDTKKTGSICLNINQWLHITMWG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6J756-1", "uniprot_id": "CAN11_MOUSE", "id": "Q6J756-1", "name": "Calpain-11", "aln": "MLN------------------------YSDISWAEKGMVATINHSRLKDKG-----------------------------VGQHQNAYNYKN--QNYEDLRAECLRKGELFEDPFFPAEPRSIGVKNLGPNSEHMQNIYWQRPKDIIHNPQFITNDFSPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRNQSFKKNYAGIFHFQLWQFGHWLNVVVDDRLPTRNNKLVFVHASHRQDFWSALLEKAYAKLIGSYGALSGGSTLEGLEDFTGGVAQCIPLQKPPGNMLRLLKKALEKSSLMGCSIEVT------------------------------------------------DNSEVETMTHNMLVRGHAYAVTGLEDVYYRDKL----ETLIRIQNPWG-RVEWNGAWSDKATEWEEVSPDVRVQLLHK-KDDGDFWMSYEDFMSNFTLLEICNLTPDALNTWDYKS---RWHSTFYEGSWRRGSTAGGCRNHPETFWSNPQFKISLPEVDDPEDDSEK-------------------NEMVCTCLVALMQKNWRHARE-GPQLLTIGFVIFSVP-KEFQNLRDIHLKKDFFLKYRDHGFSEIFINSREVNSHLRLPPGEYVIIPSTYEPHKDADFLLRVFTEKHSETWLLDDANRFEHLQ-----------------------------------------------EETVTDKDLDKDSLQLFKIMAN------------EDGEVDMYALHKLLNR----------MTAKL-RNFKTK-----------------------------------------------------------------GFSLEVCRRMINLLDKDGSGKLELHEFQVLWKKIKKWTEIFKECDEDRSGNLNSYEMRLAIEKA--------GIKMNNRVTEVVVARYSDN-MIVDFDSFLNCFLRLKAMFAFFLSMDTKKTGSICLDINQWLQITMWG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMQ6-1", "uniprot_id": "CAN11_HUMAN", "id": "Q9UMQ6-1", "name": "Calpain-11", "aln": "MLYSPGPSLPESAESLDGSQEDKPRGSCAEPTFTDTGMVAHINNSRLKAKG-----------------------------VGQHDNAQNFGN--QSFEELRAACLRKGELFEDPLFPAEPSSLGFKDLGPNSKNVQNISWQRPKDIINNPLFIMDGISPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIFHFQIWQFGQWVNVVVDDRLPTKNDKLVFVHSTERSEFWSALLEKAYAKLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCSIEVT------------------------------------------------SDSELESMTDKMLVRGHAYSVTGLQDVHYRGKM----ETLIRVRNPWG-RIEWNGAWSDSAREWEEVASDIQMQLLHK-TEDGEFWMSYQDFLNNFTLLEICNLTPDTLS-GDYKS---YWHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEG-------------------NVVVCTCLVALMQKNWRHARQQGAQLQTIGFVLYAVP-KEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVSSQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELDEVNYAEQLQ-----------------------------------------------EEKVSEDDMDQDFLHLFKIVAG------------EGKEIGVYELQRLLNR----------MAIKF-KSFKTK-----------------------------------------------------------------GFGLDACRCMINLMDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKA--------GIKLNNKVMQVLVARYADDDLIIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTMWG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35920-1", "uniprot_id": "CAN9_RAT", "id": "O35920-1", "name": "Calpain-9", "aln": "----------------------------------MPYLHR---SLRPQPQP-----------------------------VPRDARTVHSSG--HSFEQLRQSCLQSGTLFEDADFPASNSSLFYSERPQ-----VPFVWKRPGEIVENPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVVPQDQGFGSGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAENFQIREAPEDFYEILEKALRRGSLLGCSIDT------------------------------------------------LNASESEARTPLGLIKGHAYTVTGLDQVNFHGQR----IKLIRVRNPWG-QVEWNGPWSDSSPEWRSMSLEEQKRLGHTALDDGEFWMAFEDFKTHFDKVEICNLTPDALEDNTLH----KWEVTIHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTERDEGQEG--------------------------CTFLAALMQKDRRRLKRFGANMLTIGYAIYQCP----DKDG--HLNRDFFRYHASLARSKTFINLREVSGRFQLPPGDYILIPSTFEPHQEADFCLRIFSEKKAVTQDLDENIDIDLPE-------------------------------------------LPKPTPQEEETEEERQFRALFRRIAG------------EDMEVSAEELEYVLNA----------VLQKK-TALKFK-----------------------------------------------------------------RLSLLSCRNIISLMDTSGNGKMEFEEFRVFWDKLRYWMDLFLQFDVDKSGTMSSYELRTALKAA--------GFQLGSHLLQLIVLRYADENLQLDFDDYLNCLVRLENASRVFQCLSVKNKDFIHLNINEFINLTMNI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D805-1", "uniprot_id": "CAN9_MOUSE", "id": "Q9D805-1", "name": "Calpain-9", "aln": "----------------------------------MPYLHR---SLRPQPQP-----------------------------VPGDARTIHSSG--QSFEQLRQGCLQSGTLFEDADFPASNVSLFYSERPQ-----VPFVWKRPGEIVEKPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALTRVVPQDQGFGSGYAGIFHFQFWQHSEWLDVVIDDRLPTFKDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAENFQIREAPEDFFEILEKALKRGSLLGCSIDT------------------------------------------------LNASESEARTSLGLIKGHAYTVTGLDQVNFHGQR----IKLIRVRNPWG-QVEWNGPWSDSSPEWRSVDLEEQKRLGHTALDDGEFWMAFKDFKIHFDKVEICNLTPDALEDSALH----RWEVTIHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTERDEGQEG--------------------------CTFLAALMQKDRRRLKRFGANMLTIGYAIYQCP----DKDG--HLSRDFFRYHASLARSKTFINLREVSERFQLPPGDYILIPSTFEPHQEADFCLRIFSEKRAVTRDLDENIDIDLPE-------------------------------------------LPKPTPQEEETEEEQQFRALFQRVAG------------EDMEVSAEELEYVLNA----------VLQKK-TALKFK-----------------------------------------------------------------RLSLLSCRNIISLMDTSGNGKLEFEEFRVFWDKLKHWMDLFLQFDVDKSGTMSSYELRTALKAA--------GFQLGGHLLQLIVLRYADEDLQLDFDDYLNCLVRLENASRVFQSLSVKNKDFIHLNINEFISLTMNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14815-1", "uniprot_id": "CAN9_HUMAN", "id": "O14815-1", "name": "Calpain-9", "aln": "----------------------------------MPYLYR---APGPQAHP-----------------------------VPKDARITHSSG--QSFEQMRQECLQRGTLFEDADFPASNSSLFYSERPQ-----IPFVWKRPGEIVKNPEFILGGATRTDICQGELGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCFIDT------------------------------------------------RSAAESEARTPFGLIKGHAYSVTGIDQVSFRGQR----IELIRIRNPWG-QVEWNGSWSDSSPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDALEEDAIH----KWEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEE--------------------------CSFLVALMQKDRRKLKRFGANVLTIGYAIYECP----DKDE--HLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPE-------------------------------------------PPKPTPPDQETEEEQRFRALFEQVAG------------EDMEVTAEELEYVLNA----------VLQKK-KDIKFK-----------------------------------------------------------------KLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAA--------GFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINEFIHLTMNI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16259-1", "uniprot_id": "CAN3_RAT", "id": "P16259-1", "name": "Calpain-3", "aln": "----------------------------------MPTVISPTVAPRTGAEPRSPGPVPHPAQGKTTEAGGGHPGGIYSAIISRNFPIIGVKE--KTFEQLHKKCLEKKVLYLDPEFPPDETSLFYSQKFP-----IQFVWKRPPEICENPRFIIGGANRTDICQGDLGDCWLLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRASDDRPSRTIVPVQYETRMACGLVKGHAYSVTGLEEALFKGEK----VKLVRLRNPWG-QVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQ----TWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSE----------------------VICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQ--HLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKTGPDKQGESPQPRPGHTDQESEEQQQFRNIFRQIAG------------DDMEICADELKNVLNT----------VVNKH-KDLKTQ-----------------------------------------------------------------GFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRNAVNDA--------GFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64691-1", "uniprot_id": "CAN3_MOUSE", "id": "Q64691-1", "name": "Calpain-3", "aln": "----------------------------------MPTVISPTVAPRTGAEPRSPGPVPHPAQGKTTEAGGGHPSGIYSAIISRNFPIIGVKE--KTFEQLRRKCLEKKVLYLDPEFPPDETSLFYSQKFP-----IQFVWKRPPEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRGSDDRPSRTIVPVQYETRMACGLVKGHAYSVTGLEEALFKGEK----VKLVRLRNPWG-QVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQ----TWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPEDSE----------------------VICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQ--HLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKAGPEKRGETPQPRPGHTDQESEEQQQFRNIFRQIAG------------DDMEICADELKNVLNT----------VVNKH-KDLKTQ-----------------------------------------------------------------GFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRNAVNDA--------GFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFNAFDKDGDGIIKLNVLEWLQLTMYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20807-1", "uniprot_id": "CAN3_HUMAN", "id": "P20807-1", "name": "Calpain-3", "aln": "----------------------------------MPTVISASVAPRTAAEPRSPGPVPHPAQSKATEAGGGNPSGIYSAIISRNFPIIGVKE--KTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFP-----IQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEK----VKLVRLRNPWG-QVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADALQSDKLQ----TWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSE----------------------VICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQ--HLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIAG------------DDMEICADELKKVLNT----------VVNKH-KDLKTH-----------------------------------------------------------------GFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDA--------GFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1H5-1", "uniprot_id": "A0A8M6Z1H5_DANRE", "id": "A0A8M6Z1H5-1", "name": "Calpain-3", "aln": "----------------------------------MPYTPSGFFCDRLIRE-------------RERRDGEGS--------LSKP---IRFSG--QDYTLLKQEYLQKKTLFEDETFPATVDSLGYKELGHKSNKVKNIVWKRPKEICDNPQFIVGGASRTDICQGDLGDCWLLAAIACLTLNDKLLYRVIPQEQSFSEQYAGIFHFQFWRYGDWVDVVVDDRIPTFNNQLVFTKSAERNEFWSALLEKAYAKLHGSYEALKGGNTAEGMEDFTGGVTEFYEMKEAPKELYKIMQKALERGSLMGCSIDS------------------------------------------------LVPARFETRTATGLVKGHAYSVTAVEECKQSQQKES-RVRLVRLRNPWG-QVEWNGPWSDNSKEWESLSKAEKEKLQQQNAEDGEFWMSFEDFKKNYTKIEICNLTPDALEDDKLH----KWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLRLLEEDDDPEDDE----------------------VACTFVVALMQKNRRKERKLGANLLTIGFSIYEVPKEMHGNKQ--HMQKEFFMSTTAKARSRAYINLREVTQRFRLSPGEYVIIPSSYEPHQEGEFILRVFSEKRNTSEEIENRIEADHPV--------------------------------------------PSPASTGEESEEDQQFLSIFQHIAGDVSTGEAVSAWGSNMEVSANELKDVLNK----------VVSKH-KDIHTE-----------------------------------------------------------------SFSRECCRSMIALMDMDGTGRLNLQEFRQLWNKIKQWQEIFKRYDFDHNDTISSYEMRNAINDAVTCLVCHSGFRLNNQLYDIITMRYANESMNVDFESFISCLVRLEGMFRAFQAFDQCGDGSIRLSVLEWLQLTMYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q11002-1", "uniprot_id": "CANA_DROME", "id": "Q11002-1", "name": "Calpain-A", "aln": "----MDDLRGFLRQAGQEFLNAAGEAAMGAAKDVVGSVINEIFIKKEADTKRVLPSIKN------------------MRVLGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPD-----RHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEAPGNLFTILQKAAERNSMMGCSIEPD-------------------------------------------------PNVTEAETPQGLIRGHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQ------------------------CTVIVALMQKNRRSKRNMGMECLTIGFAIYSLNDRELENRP---QGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEENDDHVGYGGKADTITPG----------------------------------------FPTPKPIDPQKEGLRRLFDSIAG------------KDMEVDWMELKRILDHSMRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGLLSLICGPFLKGTPFEEQLGMNDQSNKRLIGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSA--------GYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIERTIYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZJZ8-1", "uniprot_id": "D3ZJZ8_RAT", "id": "D3ZJZ8-1", "name": "Calpain-12", "aln": "----------------------------------MASGNRKVTIQLVDDGAA-----------------------------AGAGGPQLFKG--QNYEAIRAACLDSGILFRDPCFPAGPDALGYDKLGPDSEKAKGVEWKRPHEFCAEPQFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPPGQGFQDGYAGVFHFQLWQFGRWVDVVVDDKLPVRDGKLLFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNTPGVFAALRHALAKESLVGATALSD---------------------------------------------------RGEIRTDEGLVKGHAYSVTGTHKMSLGFTK----VRLLRLRNPWG-RVEWSGPWSDSCPRWDMLPSEWRDALLVK-KEDGEFWMELQDFLTHFNTVQICSLSPEVLGPSPAGG---GWHIHTFQGRWVRGFNSGGSQPSAENFWTNPQFRLTLLEPDEEEDEDDEEGPWGGWGAAGAR-PARGGRVPKCTVLLSLIQRNRRCLRAKGLTYLTVGFHVFQIP-EELLGLWDSPRSRALLPGLLRADRS-VFCARRDVSRRCRLPPGHYLVVPSASRVGDEADFTLRIFSERSHTAVEIDDVISADLDA------------------------------------------------LQAPYKPLELELAQLFLELAG------------EEEELNALQLQTLISI----------ALEPARNNTRTSG----------------------------------------------------------------EIGLRTCEQLVQCFGRGQ--RLALYHFQELWGHLLSWQATFDKFDEDASGTMNSCELRLALTAA--------GFHLNNQLTQALTSRYRNSRLRVDFEHFVCCAARLTCIFRHCCQHLDGGEGVVCLTHKQWSEVATFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER56-1", "uniprot_id": "CAN12_MOUSE", "id": "Q9ER56-1", "name": "Calpain-12", "aln": "----------------------------------MASGNRKVTIQLVDDGAG-----------------------------TGAGGPQLFKG--QNYEAIRRACLDSGILFRDPCFPAGPDALGYDKLGPDSEKAKGVEWKRPHEFCAEPQFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPPGQGFQDGYAGVFHFQLWQFGRWVDVVVDDKLPVREGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNTPGVFAALRHALAKESLVGATALSD---------------------------------------------------RGEIRTDEGLVKGHAYSVTGTHKMSLGFTK----VRLLRLRNPWG-RVEWSGPWSDSCPRWDMLPSEWRDALLVK-KEDGEFWMELQDFLTHFNTVQICSLSPEVLGPSPAGG---GWHIHIFQGRWVRGFNSGGSQPSAENFWTNPQFRLTLLEPDEEEDDDDEEGPWGGWGAAGARGPARGGRVPKCTVLLSLIQRNRRCLRAKGLTYLTVGFHVFQIP-EELLDLWDSPRSRALLPGLLRADRS-VFCARRDVSRRCRLPPGHYLVVPSASRVGDEADFTLRIFSERSHTAVEIDDVISADLDA------------------------------------------------LQAPYKPLELELAQLFLELAG------------EEEELNALQLQTLISI----------ALEPARANTRTPG----------------------------------------------------------------EIGLRTCEQLVQCFGRGQ--RLSLHHFQELWGHLMSWQATFDKFDEDASGTMNSCELRLALTAA--------GFHLNNQLTQSLTSRYRDSRLRVDFERFVGCAARLTCIFRHCCQHLDGGEGVVCLTHKQWSEVATFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSI9-1", "uniprot_id": "CAN12_HUMAN", "id": "Q6ZSI9-1", "name": "Calpain-12", "aln": "----------------------------------MASSSGRVTIQLVDEEAG-----------------------------VGAGRLQLFRG--QSYEAIRAACLDSGILFRDPYFPAGPDALGYDQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRLLRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGATALSD---------------------------------------------------RGEYRTEEGLVKGHAYSITGTHKVFLGFTK----VRLLRLRNPWG-CVEWTGAWSDSCPRWDTLPTECRDALLVK-KEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGG---GWHVHTFQGRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEE-DDEDEEGPWGGWGAAGARGPARGGRTPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIP-EELLGLWDSPRSHALLPRLLRADRS-PLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS------------------------------------------------LQGPYLPLELGLEQLFQELAG------------EEEELNASQLQALLSI----------ALEPARAHTSTPR----------------------------------------------------------------EIGLRTCEQLLQCFGHGQ--SLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAA--------GFHLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : *: * **. :: . * ** :: .* *: . . *: ** **:**:*** . ** : **:* *.* ***:***::*:.. *:::::** :* .*:: :: . .:**..*:******: *.* .: ** *.: *****: : . . : :* *::*. * *::.***::* ::*::**** **.* *.* * : : : **:*** :* .: ::**.*:.: * * .* * * .:**. .: *** : * : *: . *: : .*:*:. * : * ::*: :: .: : *:* : * *..*:::**: ...* :*.*:* . : . . :: *. :: : *. :: :. . : .* : : : * . . :. ::* .: * * : : : : *: : *: :: * :: : .: ", "identical_positions": 125, "similar_positions": 166, "identity": "12.61%" }, { "cls_id": "homologset.agr.FB:FBgn0012058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8A2-1", "uniprot_id": "CDC27_RAT", "id": "Q4V8A2-1", "name": "Cell division cycle protein 27 homolog", "aln": "----------------------MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEE--------ALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSG---GVFNKQKSHDDLVTEFGDSACFT------LSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSSCLPNTCTA------LVSNHSLSHRQPETVLT--------------ETPQDTIELNRLNLESS-------NSKYSLNTDSSVSYIDSAVISP-------DNVPLGTGPSILSKQVQNK------PKTG---RSLLGGPTALSPLTPSFGILPLETPSPG-DGSYLQNYTNTPSVIDVPSTGAPTKKS-VARMGHTGAKSVFSQSGNSRE---ATPVLVAQTQSSGPQTSTTPQVLSP---TITSPPNALPRRSSRLFTSDSSTTKEN-SKKLKMKFP-PKIPNRKTKSKTNKGGITQPNINDS---------LEITKLDSS-----------------IISEGKISTITPQIQAFNLQKAAAG-LMSLLREMGKGYLALCSYNCKEAINILS-HLPSHHYSTG-WVLCQIGRAYFELSEYMQAERIFSEVRRIESFRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A6Q5-1", "uniprot_id": "CDC27_MOUSE", "id": "A2A6Q5-1", "name": "Cell division cycle protein 27 homolog", "aln": "----------------------MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEE--------ALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSG---GVFNKQKSHDDLVTEFGDSACFT------LSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKLTSLQNFSSCLPNTCTT------LVSNHSLSHRQPETVLT--------------ETPQDTIELNRLNLESS-------NSKYSLNTDSSVSYIDSTVISP-------DNVPLGPGTAILSKQVQNK------PKTG---RSLLGGPTALSPLTPSFGILPLETPSPG-DGSYLQNYTNTPSVIDVAPTGAPTKKS-VARMGQTGTKSVFSQSGNSRE---VTPVLVAQTQSSGPQTSTTPQVLSP---TITSPPNALPRRSSRLFTSDSSTTKEN-SKKLKMKFP-PKIPNRKTKSKTNKGGLTQPSINDS---------LEITKLDSS-----------------IISEGKITTVTPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILS-HLPSHHYSTG-WVLCQIGRAYFELSEYMQAERIFSEVRRIESFRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30260-1", "uniprot_id": "CDC27_HUMAN", "id": "P30260-1", "name": "Cell division cycle protein 27 homolog", "aln": "----------------------MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEE--------ALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSG---GVFNKQKSHDDIVTEFGDSACFT------LSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTT------QVPNHSLSHRQPETVLT--------------ETPQDTIELNRLNLESS-------NSKYSLNTDSSVSYIDSAVISP-------DTVPLGTGTSILSKQVQNK------PKTG---RSLLGGPAALSPLTPSFGILPLETPSPG-DGSYLQNYTNTPPVIDVPSTGAPSKKS-VARIGQTGTKSVFSQSGNSRE---VTPIL-AQTQSSGPQTSTTPQVLSP---TITSPPNALPRRSSRLFTSDSSTTKEN-SKKLKMKFP-PKIPNRKTKSKTNKGGITQPNINDS---------LEITKLDSS-----------------IISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILS-HLPSHHYNTG-WVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS37-1", "uniprot_id": "Q9VS37_DROME", "id": "Q9VS37-1", "name": "Cell division cycle protein 27 homolog", "aln": "-----------------------MMIQEPVQAAIWHCLNYYDFKDAVFLSERLCSEVESDE--------TIFLLATSYFRSNQVHQAYWLLKEKARRSPQCRFLQAKCAYELKKYAEAESALIS---TGFADAKNCDELQRDFGDLACFA------YQLMAQICMRTERNKLAVSALRRALKLNPFMWHAFADLCLLGQDTDAAAIFQIHSTDVFNTCQGSSVNANAMVLFGAEQQGQQHQERQSLITNLSNVSNYILTTPVDQQQQQINQNQNQHHNSNMVTPINNNNNNNNLNSSISMLRGGLVQNSSMLAMLEDTPMGAPQDPAGQYQQNQQLY--DMSSGTPFRKQFKYLSAISPPTPSFGIMPLTSPCTGNDGSFIGNHTPVMNISYSPMPQMLVEVNQEPKMMGKKLKTHVGGLINRKEGSLNKPAVFTQAGNITPRTPNNNNVGNNGNMNVPPNPNAAVRRSSRLFSNSYSVKENNKSPNIANKFVQPRSPPRKAKSRMTKICLNNELIEDKSHHLSEKRKEKVETITSSGANNNSGGRSAAEEAKVLLNNSLNNAQTMAHQLMGLKKQSADGLMALLRGLAEAYQLLSNFQCKAAIKQLETTIPKHHLNSS-WVQSLIGLARYEMREYEAAVAIFETIHKTEPCRLDYMEIYSSSLWHLQREVELSALAQDLINQDKTSPVTWCVSGNCFSLQKEHETAIKFFKRAVQVDPDFVYSYTLLGHELVLTEEFDKAMDYFRAAVVRDPRHYNAWYGIGTIYSKQEKYELAEIHYVKALKINPQNSVILVHIGAMQFYMKKKDLSLQTLNTAATLDPKNPLTRFHRGSIYFSLGKYQEALRELEELKEVVPKESVVFYLIGKIHKTLGNMDLALMHFSWATDLDPKGANNQIKDAFDSMAHPSCCPANTTALDVDLEPTSERS--DDSTQAQQDGSYDSDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38042-1", "uniprot_id": "CDC27_YEAST", "id": "P38042-1", "name": "Anaphase-promoting complex subunit CDC27", "aln": "MAVNPELAPFTLSRGIPSFDDQALSTIIQLQDCIQQAIQQLNYSTAEFLAELLYAECSILDKSSVYWSDAVYLYALSLFLNKSYHTAFQISKEFKEYHLGIAYIFGRCALQLSQGVNEAILTLLSIINVFSSNSSNTRINMVLNSNLVHIPDLATLNCLLGNLYMKLDHSKEGAFYHSEALAINPYLWESYEAICKMRATVDLKRVFFDIAGKKSNSHNNNAASS-------FPSTSLSHFEPRSQPS--------------------------LYSKT-------NKNGNNNINNNVNTLFQSSNSP--------------PSTSASSFSSIQHFSRS------------------------------------------QQQQANTSIRTCQNKNTQTPKN--PAINSKTSSALPN----------NISMNLVSPSSKQPTISSLAKVYNR--------NKLLTTPPSKLLNNDRNHQNNNNNNNNNNNNNNNNNNNNNNNNIINKTTFKTPRNLYS----------STGRLTTS----------------------KKNPRSLIISNSILTSDYSITLPEIMYNFALILRSSSQYNSFKAIRLFESQIPSHIKDTMPWCLVQLGKLHFEIINYDMSLKYFNRLKDLQPARVKDMEIFSTLLWHLHDKVKSSNLANGLMDTMPNKPETWCCIGNLLSLQKDHDAAIKAFEKATQLDPNFAYAYTLQGHEHSSNDSSDSAKTCYRKALACDPQHYNAYYGLGTSAMKLGQYEEALLYFEKARSINPVNVVLICCCGGSLEKLGYKEKALQYYELACHLQPTSSLSKYKMGQLLYSMTRYNVALQTFEELVKLVPDDATAHYLLGQTYRIVGRKKDAIKELTVAMNLDPKGNQ-VIIDELQKCHMQE--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* :.:: : * **:* * :* : :::* * . : . . : *: : * :: .:*. :*.: .: * . .. : :.. . *:.:: : :: . .:* :**::* .: :* : * * : . .. .: .: . . .* : .: : .: *.: . * :..:. : . .. . : : : . . : . .: . . ... . * .. :* . : .*:*:... . ::* . : : . .: :. .* :. . . : :* .. : . * . : * :: :. ..::. **. :. :*.* .: * :* :*: :* : *. :: : *:. ***:*: ****: .* * *::.* : ..* :** ** :***::*: *** *::* *:**::.*:*** *** .:. *.* :* *: :*:****:**:* * ::. * ::: ** .*** . *:: * : .: :*: : * ::*...* ::: ..: :: :*: **: :*** ::**.:: ..:*:*: :: :*. . *: .:: * :***** : * : ::. . ", "identical_positions": 125, "similar_positions": 253, "identity": "13.23%" }, { "cls_id": "homologset.agr.FB:FBgn0013269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38911-1", "uniprot_id": "FKBP3_YEAST", "id": "P38911-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "MSDLLPLATYSLNVEPYTPVPAIDVTMPITVRITMAALNPEAIDEENKPSTLRIIKRNPDFEDDDFLGGDFDEDEIDEESSEEEEEEKTQKK--KKSKGKKAE-SESEDDEEDDDEDDEFQESVLLTLSPEAQYQQSLDLTITPEEEVQFIVTGSYAISLSGNYVKHPFDTPMGVEGEDEDEDADIYDSEDYDLTPDEDEIIGDDMDDLDDEEEEEVRIEEVQEEDEEDNDGEEEQEEEEEEEQKEEVKPEPKKSKKEKKRKHEEKEEEKKAKKVKKVEFKKDLEEGPTKPKSKKEQDKHKPKSKVLEGGIVIEDRTIGDGPQAKRGARVGMRYIGKLK-NGKVFDKNTSGKPFAFKLGRGEVIKGWDIGVAGMSVGGERRIIIPAPYAYGKQ-ALPGIPANSELTFDVKLVSMKN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06205-1", "uniprot_id": "FKBP4_YEAST", "id": "Q06205-1", "name": "FK506-binding protein 4", "aln": "MSDMLPLATYSLNVEPYSPTPALNFKIPVTIRITMAAIDPEPFDDDKKPSTLRIIKRNPELTRGEYYNQDNN-DGLEEDESESEQEADVPKRSVKSKKGKAVEQSESEDSEDENEIDDEFEECVLLTLSPKGQYQQALDITIAPEEDVQFVVTGSYTISLTGNYVKHPFDNSS-----DSDEDEEDYYS-------DEESSNGEEEEEEEEEDDEELSSGDDDLDDLVDASDIESR--LDELVKKDEKK---KNNKKDSKRKHEEDEEESAKPAEKKQTTKKDKKAEKVK---DSEESKPKPKTKLLEGGIIIEDRVTGKGPHAKKGTRVGMRYVGKLK-NGKVFDKNTKGKPFVFKLGQGEVIKGWDIGVAGMAVGGERRIVIPAPYAYGKQ-ALPGIPANSELTFDVKLVSMK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54397-1", "uniprot_id": "FKB39_DROME", "id": "P54397-1", "name": "39 kDa FK506-binding nuclear protein", "aln": "-----MSMFWGLNMK---PERKYSQTIIKSFHISGVALD------KGQEAKLYLAAEKQEYIVATVT-KAIPQVALDLNFSKGDRIMFYTAGDASVSLLGYLHDIDSEDDEDDDQMTIENLLNSKAIKNSK-KSEDDEDENESGEEDEEDTDDDSQIIEEYESFLEN-----------GEEEDDDDVDE-------DNEESGEEDEQDSDDSEAEEEQPKAKVAKLSPGASAKKSGKEQNGVAKKEEAK----QQQKKKEKPEAKKEQPKAKEPAKQQPASKD--------------------PRTITGGVKIVDQVVGKGEEAKQGKRVSVYYIGRLQSNNKTFDSLLKGKPFKFALGGGEVIKGWDVGVAGMKVGGKRVITCPPHMAYGARGAPPKIGPNSTLVFEVELKAVH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.**:: * . .: :.:*: .*:: . : :.* : .: : :: : *: :. . . . :***.*:::: * ..: : :: * . : **: : .* *. .:::: ..:** : . *::. :: :: ::.: ** . . . :. : :*:* * :.:*..:: . :.*: . *: .** .: : **: * *:. *.* .**:* **.: *:*:*: *.*.**. .**** * ** ********:***** ***:* * *. *** : * * * .** *.*:*:* ::: ", "identical_positions": 86, "similar_positions": 121, "identity": "20.67%" }, { "cls_id": "homologset.agr.FB:FBgn0013275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P82910-1", "uniprot_id": "HSP70_DROME", "id": "P82910-1", "name": "Heat shock 70 kDa protein Aa", "aln": "-MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAP-AGKLDEADKNSVLDKCNDTIRWLDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGA--GAGG-----PGANCGQQAGGFGGYSGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***********. : :.:*:*************:*.***:******.****.*:** ************:::**:: * **:***::. .*** : **:***:* *:**:****:* ******* :** :.***:****************** ***:*************:******: : *: **************:*:*::* :***::*************.***..: ***** ***: .* *:*******.*****:****:::::***:**** ****.::*************.**:****.* *:*:**.*:.:************:*.*: *:*:**: * *******************:**:* . **:**:**************:***** **. ** *::: *********** ***:****: ***** **.*:**************:****:*:******** * .***:::***.*******: :*::** ****: :**:. :*: ::* *** .:.:*:::.: *: : * : .:::* ***:. :* .:*:..: :** ..***:*:: .... * ** . ********", "identical_positions": 407, "similar_positions": 148, "identity": "62.52%" }, { "cls_id": "homologset.agr.FB:FBgn0013276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02825-1", "uniprot_id": "HSP71_DROME", "id": "P02825-1", "name": "Heat shock 70 kDa protein Ab", "aln": "-MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAP-AGKLDEADKNSVLDKCNDTIRWLDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGA--GAGG-----PGANCGQQAGGFGGYSGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***********. : :.:*:*************:*.***:******.****.*:** ************:::**:: * **:***::. .*** : **:***:* *:**:****:* ******* :** :.***:****************** ***:*************:******: : *: **************:*:*::* :***::*************.***..: ***** ***: .* *:*******.*****:****:::::***:**** ****.::*************.**:****.* *:*:**.*:.:************:*.*: *:*:**: * *******************:**:* . **:**:**************:***** **. ** *::: *********** ***:****: ***** **.*:**************:****:*:******** * .***:::***.*******: :*::** ****: :**:. :*: ::* *** .:.:*:::.: *: : * : .:::* ***:. :* .:*:..: :** ..***:*:: .... * ** . ********", "identical_positions": 407, "similar_positions": 148, "identity": "62.52%" }, { "cls_id": "homologset.agr.FB:FBgn0013277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8INI8-1", "uniprot_id": "HSP72_DROME", "id": "Q8INI8-1", "name": "Major heat shock 70 kDa protein Ba", "aln": "-MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVYNVKQSVEQAP-AGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELARHCSPIMTKMHQQGAGAAGGPGANCGQQAG--------GFGGYSGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***********. : :.:*:*************:*.***:******.****.*:** ************:::**:: * **:***::. .*** : **:***:* *:**:****:* ******* :** :.***:****************** ***:*************:******: : *: **************:*:*::* :***::*************.***..: ***** ***: .* *:*******.*****:****:::::***:**** ****.::*************.**:****.* *:*:**.*:.:************:*.*: ::*:**: * *******************:**:* . **:**:**************:***** **. ** *::: ****:****** ***:****: ***** **.*:**************:****:*:******** * .***:::***.*******: :*::** ****: :**:. :*: ::* *** .:.:*:::.: *: : * : .:::* ***:. :* .:*:..: :** ..***:*:: .... * .* ********", "identical_positions": 404, "similar_positions": 150, "identity": "62.06%" }, { "cls_id": "homologset.agr.FB:FBgn0013278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "MS----KAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "MS----KAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "MS----KAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "MS----RAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P17066-1", "uniprot_id": "HSP76_HUMAN", "id": "P17066-1", "name": "Heat shock 70 kDa protein 6", "aln": "MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAG-VFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYG-GPGVPGG--SSCGTQAR--------QGDPSTGPIIEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BIS2-1", "uniprot_id": "HSP73_DROME", "id": "Q9BIS2-1", "name": "Major heat shock 70 kDa protein Bb", "aln": "MP-----AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAG--------GFGGYSGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:***********. : :.:*:*:***********:*.***:***:**.**.*.*:** ************:: *. : * **:**:::. .*** : * ::** * * **:****:* ******* :** :..**:****************** ***:*************:*****:. *: **************:*:*: * :***::*************.***..: **:** **: * *:*******.*****:****:::::***:**** ****.::********:****.**:****.* *:*:**.*:.::***********:*.*: ::*:**: * *****************:* **:. . **:**:********:*****:**.** **. ** *::: *:**:****** ***:****: ***** ** *:**************:****:*:****.*:* : .***:::***.*******: ::::** ***:: :** . :*: ::* **: .: :* :: * *: : * : ..:.: **: . * .:*:..: .** . **::::: . . . ** :****", "identical_positions": 374, "similar_positions": 158, "identity": "57.1%" }, { "cls_id": "homologset.agr.FB:FBgn0013279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "MS----KAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "MS----KAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGGAP---EGAAPGGFPG-----GAPPAPEAEGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "MS----KAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGA-PGAG----PVPG--AGAGPTG-APDNGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P09435-1", "uniprot_id": "HSP73_YEAST", "id": "P09435-1", "name": "Heat shock protein SSA3", "aln": "MS----RAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGES-GGFPGSMPNSGATGGGEDTGPTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P17066-1", "uniprot_id": "HSP76_HUMAN", "id": "P17066-1", "name": "Heat shock 70 kDa protein 6", "aln": "MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAG-VFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYG-GPGVPGG--SSCGTQAR--------QGDPSTGPIIEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BIR7-1", "uniprot_id": "HSP75_DROME", "id": "Q9BIR7-1", "name": "Major heat shock 70 kDa protein Bc", "aln": "MP-----AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAG--------GFGGYSGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:***********. : :.:*:*:***********:*.***:***:**.**.*.*:** ************:: *. : * **:**:::. .*** : * ::** * * **:****:* ******* :** :..**:****************** ***:*************:*****:. *: **************:*:*: * :***::*************.***..: **:** **: * *:*******.*****:****:::::***:**** ****.::********:****.**:****.* *:*:**.*:.::***********:*.*: ::*:**: * *****************:* **:. . **:**:********:*****:**.** **. ** *::: *:**:****** ***:****: ***** ** *:**************:****:*:****.*:* : .***:::***.*******: ::::** ***:: :** . :*: ::* **: .: :* :: * *: : * : ..:.: **: . * .:*:..: .** . **::::: . . . ** :****", "identical_positions": 374, "similar_positions": 158, "identity": "57.1%" }, { "cls_id": "homologset.agr.FB:FBgn0013303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84076-1", "uniprot_id": "HPCA_RAT", "id": "P84076-1", "name": "Neuron-specific calcium-binding protein hippocalcin", "aln": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84074-1", "uniprot_id": "HPCA_HUMAN", "id": "P84074-1", "name": "Neuron-specific calcium-binding protein hippocalcin", "aln": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84075-1", "uniprot_id": "HPCA_MOUSE", "id": "P84075-1", "name": "Neuron-specific calcium-binding protein hippocalcin", "aln": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62748-1", "uniprot_id": "HPCL1_MOUSE", "id": "P62748-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62749-1", "uniprot_id": "HPCL1_RAT", "id": "P62749-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37235-1", "uniprot_id": "HPCL1_HUMAN", "id": "P37235-1", "name": "Hippocalcin-like protein 1", "aln": "MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61601-1", "uniprot_id": "NCALD_HUMAN", "id": "P61601-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PQN0-1", "uniprot_id": "NCALD_RAT", "id": "Q5PQN0-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X97-1", "uniprot_id": "NCALD_MOUSE", "id": "Q91X97-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9JTH1-1", "uniprot_id": "NCLDA_DANRE", "id": "A9JTH1-1", "name": "Neurocalcin-delta A", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGNLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIKGAKTDPSIVRLLQCDPSSAGQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AXL4-1", "uniprot_id": "NCLDB_DANRE", "id": "Q6AXL4-1", "name": "Neurocalcin-delta B", "aln": "MGKQNSKLRPEVIQDLLDNTDFTEHEILEWYKGFLRDCPSGALSMDEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGRLDQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNRDGKLSLEEFVEGAKNDPSIVRLLQCDPSSAGQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42325-1", "uniprot_id": "NCAH_DROME", "id": "P42325-1", "name": "Neurocalcin homolog", "aln": "MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQSH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06389-1", "uniprot_id": "NCS1_YEAST", "id": "Q06389-1", "name": "Calcium-binding protein NCS-1", "aln": "MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.*** : : * : * * *: :*:****:***:* * ::* *** :***:*....**:*:* .** :.:* *.*.**: .**.**** *::** ***.:***: :***: *** ** ::***:.*::.: ***:*** *..***: ** *.** ::*:** .*:* ****: *: ", "identical_positions": 90, "similar_positions": 56, "identity": "46.63%" }, { "cls_id": "homologset.agr.FB:FBgn0013307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08432-1", "uniprot_id": "DCOR_YEAST", "id": "P08432-1", "name": "Ornithine decarboxylase", "aln": "MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDP--GEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMEN-VDVLLKAIK-ELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQFES-----FKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKRKLS----------ENE-----AMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYY-MKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD-----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40807-1", "uniprot_id": "DCOR1_DROME", "id": "P40807-1", "name": "Ornithine decarboxylase 1", "aln": "---------------------MAAATPEIQFYER---------ELN------------------------IRRVIEECDLQ--RLDQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLGAGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNSNLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAK-SLELKVTGTSFHVGSGCSELQAYDRAIKKAKNLFKFGALLG--YDMDFLDIGGGFPGSDDV--KFEKIAESVNTSVQRHFPDER-VHIIAEPGRFFVAAACTLVCKIHAKREIR----------NEAGKLDTVMYYLNDGVYGSFNCILYDHQV--------VIAEHYLDNAESLPHLKSL------------IWGPSCDALDKISEDLH-LPN-LNRGDLLGFRNMGAYTMPIASAFNGFEVPKTLYFQAI--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00860-1", "uniprot_id": "DCOR_MOUSE", "id": "P00860-1", "name": "Ornithine decarboxylase", "aln": "------------------MSSFTKDEFDCHILDEG-----------------------------FTAKDILDQKINEVSSS--DDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKT-SRLLLERAK-ELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVG--FSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKE--QPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAH---------VKALLQKRPKPDEKYYSS-----------SIWGPTCDGLDRIVERCN-LPE-MHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFPPEVEEQDDGTLPMSCAQESGMDRHPAACASARINV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09057-1", "uniprot_id": "DCOR_RAT", "id": "P09057-1", "name": "Ornithine decarboxylase", "aln": "------------------MGSFTKEEFDCHILDEG-----------------------------FTAKDILDQKINEVSSS--DDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKT-SRLLLERAK-ELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVG--FSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKE--QTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAH---------VKALLQKRPKPDEKYYSS-----------SIWGPTCDGLDRIVERCS-LPE-MHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11926-1", "uniprot_id": "DCOR_HUMAN", "id": "P11926-1", "name": "Ornithine decarboxylase", "aln": "------------------MNNFGNEEFDCHFLDEG-----------------------------FTAKDILDQKINEVSSS--DDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRT-SRLLLERAK-ELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVG--FSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKE--QTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAH---------VKPLLQKRPKPDEKYYSS-----------SIWGPTCDGLDRIVERCD-LPE-MHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LVE6-1", "uniprot_id": "F1LVE6_RAT", "id": "F1LVE6-1", "name": "Antizyme inhibitor 2", "aln": "--------MTTPSEGRREPLGVTESLWPSEPITLG---------------------------PETSARQLVLKKIQDLSIS--GHQDPFMVADLDVLASRHQTFLQALPRVWPFYAVKCNNRPSLLLVLAALGTGFDCASQGELEQVLGLGVAPSRIIFANPCKAVSHIQYAARCGVQLLTFDSEEELTKLARHHPGARLILRIQTLGGRSTFPLHTKFGARLLA-CGRLLQVAR-ELGLAVVGASFHVGSDCHTPQSYRQAIADCHRVFEMGCKAG--HQMSLLDLGGGFPGIEGSEAKFEEMARVVNAALAQYFPEGTGVEVIAEPGRFYAESVCTAAVNIIAKKASL-----------EPGGHRKLAYYLNEGHYGAFRIFLRDPVP--------RIPIVVKELPSDPHLFPCT------------LYGPTCDAFDRLFSTEV-QLPELDVGDWLVFPDMGAYRSTMSSTFNGFPITTVYDAMSPQLRSLLETVP----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVM4-1", "uniprot_id": "AZIN2_MOUSE", "id": "Q8BVM4-1", "name": "Antizyme inhibitor 2", "aln": "-------------------MAGYLSESDFVMVEEG-----------------------------FSTRDLLEELTLGASQATSGKVAAFFVADLGAVVRKHFCFLKHLPRVRPFYAVGCNSSLGVLKVLAELGLGFSCANKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKMVLCIATQDSHSLNHLSLRFGASLKS-CRHLLENAK-KSHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFQMGEELG--HTMNILDLGGGFPGLEGAKVRFEEMASVINSALDLYFPEGCGVDILAELGRYYVTSAFTVAVSIVAKREVLD---QASREEQTGAAPKSIVYYLDEGVYGVFNSVLFDNTCP---------TPALQKKPSADQPLYSS-----------SLWGPAVEGCDCVAEGLW-LPQ-LQVGDWLVFDNMGAYTVDTKSLLGGTQARRVTYAMSRLAWEALRGQLLPAEEDQDAEGVCKPLSCGWEITDTLCVGPVFTPASIM--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A693-1", "uniprot_id": "AZIN2_RAT", "id": "D4A693-1", "name": "Antizyme inhibitor 2", "aln": "-------------------MAGYLSESDFVMVEEG-----------------------------FSTRDLLEELTLGASQATTGKVAAFFVAD--AVVRKHFCFLKYLPRVRPFYAVRCNSSLGVLKVLAELGLGFSCASKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKSWGEVLTLDALGLHHTHRRVGCSLMF-QASVIASVA-QGYLELVCQPFHIGSGCPDPQAYAQSIADARLVFQMGAELG--HTMNILDLGGGFPGLEGAKVRFEEVTSVIGKNIPFYTPPPCHVPLRTHATKKMTSSDFCCRVHVTAKEKPLF---SPFLTEQTGAAPKSIVYHLDEGVYGVFNSVLFDNTCP---------TPALQKKPSADQPLYSS-----------SLWGPAVDGCDCVAEGLW-LPQ-LQVGDWLVFDNMGAYTVDTKSLLGGTQACRVTYAMSRLAWEALQGQLLPAEEDQDAEGVCKPLSCGWEITDSLCVGPVFTPASIM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A70-1", "uniprot_id": "AZIN2_HUMAN", "id": "Q96A70-1", "name": "Antizyme inhibitor 2", "aln": "-------------------MAGYLSESDFVMVEEG-----------------------------FSTRDLLKELTLGASQATTDEVAAFFVADLGAIVRKHFCFLKCLPRVRPFYAVKCNSSPGVLKVLAQLGLGFSCANKAEMELVQHIGIPASKIICANPCKQIAQIKYAAKHGIQLLSFDNEMELAKVVKSHPSAKMVLCIATDDSHSLSCLSLKFGVSLKS-CRHLLENAK-KHHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFEMGTELG--HKMHVLDLGGGFPGTEGAKVRFEEIASVINSALDLYFPEGCGVDIFAELGRYYVTSAFTVAVSIIAKKEVLLD--QPGREEENGSTSKTIVYHLDEGVYGIFNSVLFDNICP---------TPILQKKPSTEQPLYSS-----------SLWGPAVDGCDCVAEGLW-LPQ-LHVGDWLVFDNMGAYTVGMGSPFWGTQACHITYAMSRVAWEALRRQLMAAEQEDDVEGVCKPLSCGWEITDTLCVGPVFTPASIM--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q801V3-1", "uniprot_id": "Q801V3_DANRE", "id": "Q801V3-1", "name": "", "aln": "-----------------MKGFVDAPNYFIELLEGG-----------------------------TTLENVIDNHIYEQNLA---EKNAFVVADLGALMRQHVVWKTTMPLVRPFYPVSCNSSPVVIELLSALGVGFVCANKAETTLVLSHDVPPENIILSGVCKQLSLIKHAAKTGINFLLCENEAELRKIARAHPEAKLLLQVSTE--AQIEEASVTIGCSLKG-CRHLLELAK-ELNVSVAGVTFQVPASCKDPQAYTHALSDARCIFDMGKELG--FDMNILDIGGGFSGSE---FQLKQVHSVIRPLLEAYFPSESGVSIIAEPGNFFVFSCFTLAVNVIGKKAAYRNLHTSTHDKLTSSDAPEFVYYMNDGVYGSFMGRLFGN-IISTP-------SVHKMSLTLDEPVFSS-----------SLWGPSCDPLDQVVERCL-LPE-LAVGDWLVFSNMGASGQEGPATFSDTDQPPVYYTISTDDWFEMQEAGISLDDTMKNLSLVQFGL-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N598-1", "uniprot_id": "A0A8M1N598_DANRE", "id": "A0A8M1N598-1", "name": "", "aln": "---------------MSMKGSLDELHYSVELLEGS-----------------------------AALRDVIDKHIYDQTFA---QKSAFFAADLGVIVQQQARWRNKMDQIRPFYTVKSNSSPVVVELLASLGTGFICSNKHELDLVKGFGVSSQDIILGGTCKQLSHIKYAAKHNIPLLVCDNEAEMRKIARCHPKAKVLLLLTSESCCEKEEMAIPFGSTLKD-CRRLLECAAGELNLQVTGVKFNIPSCCQEVEKFSRAVSEARCVFDMGEELG--FEMNILDIGGGFDGSE---EQLDKVNQMLKPMLDMYFPRSTGLSIIAEPGAYYVSSAFTLAVNIIDKKTVARDCSAQPHDALSANDEPEFLYHINDGVYGSFASKLLCEDSIATP-------LAHKH-VSADEPLFSS-----------SLWGPSEDDLDLVMERCL-LPE-LSVGDWLLFRNAGASALGSAFSHGDQHKPPVFYSITEYDWQEIHNSGVTVDVRMKNFSLVPCCLQPNMSGASISTPA----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14977-1", "uniprot_id": "AZIN1_HUMAN", "id": "O14977-1", "name": "Antizyme inhibitor 1", "aln": "-----------------MKGFIDDANYSVGLLDEG-----------------------------TNLGNVIDNYVYEHTLT---GKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKN-CRHLLECAK-ELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIG--FTMNMLDIGGGFTGTE---FQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEK-TGSDEPAFMYYMNDGVYGSFASKLSED-LNTIP-------EVHKK-YKEDEPLFTS-----------SLWGPSCDELDQIVESCL-LPE-LNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGITSDSMMKNFFFVPSCIQLSQE-DSFSAEA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63764-1", "uniprot_id": "AZIN1_RAT", "id": "Q63764-1", "name": "Antizyme inhibitor 1", "aln": "-----------------MKGFIDDANYSVGLLDEG-----------------------------TNLGNVIDNYVYEHTLT---GKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKN-CRHLLECAK-ELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFG--FTMNMLDIGGGFTGTE---IQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEK-NGSDEPAFVYYMNDGVYGSFASKLSED-LNTVP-------EVHKK-YKEDEPLFTS-----------SLWGPSCDELDQIVESCL-LPE-LSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGITSDAMMKNFFFAPSCIQLSQE-DNFSTEA----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABJ3HKJ7-1", "uniprot_id": "A0ABJ3HKJ7_MOUSE", "id": "A0ABJ3HKJ7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPKKRRRFTR------------LFGPLSHG--ELSDRVYNYPE----G-------LGEVLYREQFDFN--AEPP---------WEPS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** . : . * * ", "identical_positions": 4, "similar_positions": 5, "identity": "0.74%" }, { "cls_id": "homologset.agr.FB:FBgn0013308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVM4-1", "uniprot_id": "AZIN2_MOUSE", "id": "Q8BVM4-1", "name": "Antizyme inhibitor 2", "aln": "------MAGYLS-------------ESDFVMVEEGFSTRDLLEELTLGASQATS---------------------------GKVAAFFVADLGAVVRKHFCFLKHLPRVRPFYAVGCNSSLGVLKVLAELGLGFSCANKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKMVLCIATQDSHSLNHLSLRFGASLKS-CRHLLENAK-KSHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFQMGEELG--HTMNILDLGGGFPGLEGAKVRFEEMASVINSALDLYFPEGCGVDILAELGRYYVTSAFTVAVSIVAKREVLD---QASREEQTGAAPKSIVYYLDEGVYGVFNSVLFDN-TCPTP--------ALQKKPSADQP------------LYSSSLWGPAVEGCDCVA-EGLWLPQLQVGDWLVFDNMGAYTVDTKSLLGGTQARRVTYAMSRLAWEALRGQLLP--AEEDQDAEGVCKPLSCGWEITDTLCVGPVFTPASIM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A693-1", "uniprot_id": "AZIN2_RAT", "id": "D4A693-1", "name": "Antizyme inhibitor 2", "aln": "------MAGYLS-------------ESDFVMVEEGFSTRDLLEELTLGASQATT---------------------------GKVAAFFVAD--AVVRKHFCFLKYLPRVRPFYAVRCNSSLGVLKVLAELGLGFSCASKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKSWGEVLTLDALGLHHTHRRVGCSLMF-QASVIASVA-QGYLELVCQPFHIGSGCPDPQAYAQSIADARLVFQMGAELG--HTMNILDLGGGFPGLEGAKVRFEEVTSVIGKNIPFYTPPPCHVPLRTHATKKMTSSDFCCRVHVTAKEKPLF---SPFLTEQTGAAPKSIVYHLDEGVYGVFNSVLFDN-TCPTP--------ALQKKPSADQP------------LYSSSLWGPAVDGCDCVA-EGLWLPQLQVGDWLVFDNMGAYTVDTKSLLGGTQACRVTYAMSRLAWEALQGQLLP--AEEDQDAEGVCKPLSCGWEITDSLCVGPVFTPASIM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96A70-1", "uniprot_id": "AZIN2_HUMAN", "id": "Q96A70-1", "name": "Antizyme inhibitor 2", "aln": "------MAGYLS-------------ESDFVMVEEGFSTRDLLKELTLGASQATT---------------------------DEVAAFFVADLGAIVRKHFCFLKCLPRVRPFYAVKCNSSPGVLKVLAQLGLGFSCANKAEMELVQHIGIPASKIICANPCKQIAQIKYAAKHGIQLLSFDNEMELAKVVKSHPSAKMVLCIATDDSHSLSCLSLKFGVSLKS-CRHLLENAK-KHHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFEMGTELG--HKMHVLDLGGGFPGTEGAKVRFEEIASVINSALDLYFPEGCGVDIFAELGRYYVTSAFTVAVSIIAKKEVLLD--QPGREEENGSTSKTIVYHLDEGVYGIFNSVLFDN-ICPTP--------ILQKKPSTEQP------------LYSSSLWGPAVDGCDCVA-EGLWLPQLHVGDWLVFDNMGAYTVGMGSPFWGTQACHITYAMSRVAWEALRRQLMA--AEQEDDVEGVCKPLSCGWEITDTLCVGPVFTPASIM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00860-1", "uniprot_id": "DCOR_MOUSE", "id": "P00860-1", "name": "Ornithine decarboxylase", "aln": "------MSSFTKD------------EFDCHILDEGFTAKDILDQKIN--EVSSS---------------------------DDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKT-SRLLLERAK-ELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVG--FSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKE--QPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDH-AHVKA--------LLQKRPKPDEK------------YYSSSIWGPTCDGLDRIV-ERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFPPEVEEQDDGTLPMSCAQESGMDRHP-AACASARINV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09057-1", "uniprot_id": "DCOR_RAT", "id": "P09057-1", "name": "Ornithine decarboxylase", "aln": "------MGSFTKE------------EFDCHILDEGFTAKDILDQKIN--EVSSS---------------------------DDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKT-SRLLLERAK-ELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVG--FSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKE--QTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDH-AHVKA--------LLQKRPKPDEK------------YYSSSIWGPTCDGLDRIV-ERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHP-AACASASINV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11926-1", "uniprot_id": "DCOR_HUMAN", "id": "P11926-1", "name": "Ornithine decarboxylase", "aln": "------MNNFGNE------------EFDCHFLDEGFTAKDILDQKIN--EVSSS---------------------------DDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRT-SRLLLERAK-ELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVG--FSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKE--QTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDH-AHVKP--------LLQKRPKPDEK------------YYSSSIWGPTCDGLDRIV-ERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHR-AACASASINV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LVE6-1", "uniprot_id": "F1LVE6_RAT", "id": "F1LVE6-1", "name": "Antizyme inhibitor 2", "aln": "------MTTPSEGRREPLGVTESLWPSEPITLGPETSARQLVLKKIQ--DLSIS---------------------------GHQDPFMVADLDVLASRHQTFLQALPRVWPFYAVKCNNRPSLLLVLAALGTGFDCASQGELEQVLGLGVAPSRIIFANPCKAVSHIQYAARCGVQLLTFDSEEELTKLARHHPGARLILRIQTLGGRSTFPLHTKFGARLLA-CGRLLQVAR-ELGLAVVGASFHVGSDCHTPQSYRQAIADCHRVFEMGCKAG--HQMSLLDLGGGFPGIEGSEAKFEEMARVVNAALAQYFPEGTGVEVIAEPGRFYAESVCTAAVNIIAKKASLE-----------PGGHRKLAYYLNEGHYGAFRIFLRDP-VPRIP--------IVVKELPSDPH------------LFPCTLYGPTCDAFDRLFSTEVQLPELDVGDWLVFPDMGAYRSTMSSTFNGFPITTVYDAMSPQLRSLLETVP-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08432-1", "uniprot_id": "DCOR_YEAST", "id": "P08432-1", "name": "Ornithine decarboxylase", "aln": "MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMEN-VDVLLKAIK-ELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQ-----FESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKR----------KLSENE-----AMIYTNDGVYGNMNCILFDH-QEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40808-1", "uniprot_id": "DCOR2_DROME", "id": "P40808-1", "name": "Ornithine decarboxylase 2", "aln": "-------------------MVNG--DLRIQYYDEELNIR----KVIEQADLEHL-----------------------------DQALNICDLSSLERKLRLWHKLMPRIEPHYAVKCNDDPVVVKFLADLGTGFDCASKNELKLVLGLGVSPERIIFAHPCRPASHLRYAKEQQVVNGTVDNEYEIYKLRKHYPDSNLIVRFKSEAKKALCPLGDKYGCDAEADAAALMLLAK-ALGLKVTGTSFHVGSGCSEVEAYDRAIEKAENIFKVGEMIG--HKMELLDVGGGFPGID--DEMFEEIAQSVNTSVELRFPDKR-IRIISEPGRFFVEAAYTLICKVHAKR----------EVRSKDGKLDTMMYYLNDGIFGAFAGMFYYP-EEVAP-------ELYLDEAESLP-------------KLKSVIWGPSCDAMDKIS--DLLLPNLNPGDLLGFRNMGAYTMPIASPFNGFDVPETRFFKAK---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q801V3-1", "uniprot_id": "Q801V3_DANRE", "id": "Q801V3-1", "name": "", "aln": "------MKGFVDAP-----------NYFIELLEGGTTLENVIDNHIYEQNLAEK------------------------------NAFVVADLGALMRQHVVWKTTMPLVRPFYPVSCNSSPVVIELLSALGVGFVCANKAETTLVLSHDVPPENIILSGVCKQLSLIKHAAKTGINFLLCENEAELRKIARAHPEAKLLLQVSTE--AQIEEASVTIGCSLKG-CRHLLELAK-ELNVSVAGVTFQVPASCKDPQAYTHALSDARCIFDMGKELG--FDMNILDIGGGFSGSE---FQLKQVHSVIRPLLEAYFPSESGVSIIAEPGNFFVFSCFTLAVNVIGKKAAYRNLHTSTHDKLTSSDAPEFVYYMNDGVYGSFMGRLFGN-IISTP-------SVHKMSLTLDEP------------VFSSSLWGPSCDPLDQVV-ERCLLPELAVGDWLVFSNMGASGQEGPATFSDTDQPPVYYTISTDDWFEMQEAGIS--------LDDTMKNLSLVQFGL----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N598-1", "uniprot_id": "A0A8M1N598_DANRE", "id": "A0A8M1N598-1", "name": "", "aln": "----MSMKGSLDEL-----------HYSVELLEGSAALRDVIDKHIYDQTFAQK------------------------------SAFFAADLGVIVQQQARWRNKMDQIRPFYTVKSNSSPVVVELLASLGTGFICSNKHELDLVKGFGVSSQDIILGGTCKQLSHIKYAAKHNIPLLVCDNEAEMRKIARCHPKAKVLLLLTSESCCEKEEMAIPFGSTLKD-CRRLLECAAGELNLQVTGVKFNIPSCCQEVEKFSRAVSEARCVFDMGEELG--FEMNILDIGGGFDGSE---EQLDKVNQMLKPMLDMYFPRSTGLSIIAEPGAYYVSSAFTLAVNIIDKKTVARDCSAQPHDALSANDEPEFLYHINDGVYGSFASKLLCEDSIATP-------LAHKH-VSADEP------------LFSSSLWGPSEDDLDLVM-ERCLLPELSVGDWLLFRNAGASALGSAFSHGDQHKPPVFYSITEYDWQEIHNSGVT--------VDVRMKNFSLVPCCLQPNMSGASISTPA---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14977-1", "uniprot_id": "AZIN1_HUMAN", "id": "O14977-1", "name": "Antizyme inhibitor 1", "aln": "------MKGFIDDA-----------NYSVGLLDEGTNLGNVIDNYVYEHTLTGK------------------------------NAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKN-CRHLLECAK-ELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIG--FTMNMLDIGGGFTGTE---FQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEK-TGSDEPAFMYYMNDGVYGSFASKLSED-LNTIP-------EVHKK-YKEDEP------------LFTSSLWGPSCDELDQIV-ESCLLPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGIT--------SDSMMKNFFFVPSCIQLSQE-DSFSAEA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63764-1", "uniprot_id": "AZIN1_RAT", "id": "Q63764-1", "name": "Antizyme inhibitor 1", "aln": "------MKGFIDDA-----------NYSVGLLDEGTNLGNVIDNYVYEHTLTGK------------------------------NAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKN-CRHLLECAK-ELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFG--FTMNMLDIGGGFTGTE---IQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEK-NGSDEPAFVYYMNDGVYGSFASKLSED-LNTVP-------EVHKK-YKEDEP------------LFTSSLWGPSCDELDQIV-ESCLLPELSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGIT--------SDAMMKNFFFAPSCIQLSQE-DNFSTEA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABJ3HKJ7-1", "uniprot_id": "A0ABJ3HKJ7_MOUSE", "id": "A0ABJ3HKJ7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPKKRRRFTRLFG--------PLSHGELSDR----------------------VYNYPEG-LG---EVLYRE----------------QFDFNAEPP------------------WEPS--------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .. :* * : : *: ", "identical_positions": 4, "similar_positions": 7, "identity": "0.74%" }, { "cls_id": "homologset.agr.FB:FBgn0013325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62913-1", "uniprot_id": "RL11_HUMAN", "id": "P62913-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62914-1", "uniprot_id": "RL11_RAT", "id": "P62914-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXW4-1", "uniprot_id": "RL11_MOUSE", "id": "Q9CXW4-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAQ-----DQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46222-1", "uniprot_id": "RL11_DROME", "id": "P46222-1", "name": "Large ribosomal subunit protein uL5", "aln": "MAAVTKKIKRDPAKNPMRDLHIRKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILERGLKVREYELRRENFSSTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGYNVNHRKRKSGTVGFQHRLTKEDAMKWFQQKYDGIILNTKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0W9-1", "uniprot_id": "RL11A_YEAST", "id": "P0C0W9-1", "name": "Large ribosomal subunit protein uL5A", "aln": "MSA--------KAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTVSWFKQKYDADVLDK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3E757-1", "uniprot_id": "RL11B_YEAST", "id": "Q3E757-1", "name": "Large ribosomal subunit protein uL5B", "aln": "MST--------KAQNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTTKEDTVSWFKQKYDADVLDK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :****:*:*.** ***.***********:******:** ** ********:************ ****.*******:****:**:** .*** ********:***************:*:*****:.*** : :** .* :* .*: :**::: **:****. :* ", "identical_positions": 121, "similar_positions": 32, "identity": "65.76%" }, { "cls_id": "homologset.agr.FB:FBgn0013334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F350-1", "uniprot_id": "F7F350_RAT", "id": "F7F350-1", "name": "Synapse-associated protein 1", "aln": "MFRGLSSWLG--------------LKQPEGAAA-GEEPPS--GDKLSSGAAPPEKSSEGLVEPTEEEEQ--------------LTEDPQFLHQAKGLG---------------------------------------------------------------------NYLYSFASAATK-----------------------KITESVTETAQTIKKSVEEGK-------IDDILDKTIIGDFQKEQKKFVEEQHTKKSEAAVPPWVESHDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSKMRFALVPKLVKEEVFWRNYFYRISLIKQSAQLTALAAQ-----------QQASGKEEKSSSRD-------------DNLPLTEAVRPKTPPVVIKSQLKNQEDE-EEISTSPGVSEFVSDAFDACN-LNQEDLRKEMEQLVLDKKQEEATALEEDSTDWEKELQQELQEYEVVAE-----------------------------------SEKRDENWDKEIEKMLQES---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5V6-1", "uniprot_id": "SYAP1_MOUSE", "id": "Q9D5V6-1", "name": "Synapse-associated protein 1", "aln": "MFGGLSSWLG--------------LKPPEGAAAEGEEPPSRDGDKLSAGAAPSEESPERPVEPTEEQQQQP------------PTEDPQFLHQAKGLG---------------------------------------------------------------------NYLYNFASAATK-----------------------KITESVTETAQTIKKSVEEGK-------IDDILDKTILGDFQKEQKKFVEEQNTKKSEAAVPPWVESHDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSKMRFALVPKLVKEEVFWRNYFYRISLIKQSAQLTALAAQ-----------QQASGKEEKSSNRD-------------DNLPLTEAVRPKTPPVVIKSQLKSQEDE-EEISTSPGVSEFVSDAFDTCS-LNQEDLRKEMEQLVLDKKQEEATALEEDSTDWEKELQQELQEYEVVAE-----------------------------------SEKRDENWDKEIEKMLQES---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A49-1", "uniprot_id": "SYAP1_HUMAN", "id": "Q96A49-1", "name": "Synapse-associated protein 1", "aln": "MFRGLSSWLG--------------LQQPVAGGG----QPN--------GDAPPEQPSETVAESAEEELQ--------------QAGDQELLHQAKDFG---------------------------------------------------------------------NYLFNFASAATK-----------------------KITESVAETAQTIKKSVEEGK-------IDGIIDKTIIGDFQKEQKKFVEEQHTKKSEAAVPPWVDTNDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSKMRFALVPKLVKEEVFWRNYFYRVSLIKQSAQLTALAAQ-----------QQAAGKEEKSNGRE-------------QDLPLAEAVRPKTPPVVIKSQLKTQEDE-EEISTSPGVSEFVSDAFDACN-LNQEDLRKEMEQLVLDKKQEETAVLEEDSADWEKELQQELQEYEVVTE-----------------------------------SEKRDENWDKEIEKMLQEEN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q960T2-1", "uniprot_id": "SAP47_DROME", "id": "Q960T2-1", "name": "Synapse-associated protein of 47 kDa", "aln": "MFSGLTNQFTSLVGAVKGGAGDEDVPAPTGDAPAAAPAASTSVEATASSAVDPEAAAAAGGEGLEGEEAGKRLPKSASLVDSLVSEATGWLGSAKGWLGNASIPSMPAMPSMPSMPAMPAMPSIPSIPGLRKGAGADGAEGAEGAVAGEGGAAASGAVSGGEDDDKSRYISATEGADSHPASGGGTPTGDEGQIGQGKGDEVKITTKVTQQAKHFGSFLSSAISKAGSKIKETVKDNTILDSFNKEQEAFIKGQGGVGN--GAAPWIGHANEAKIKEEILGLSQDRRNFVRAPPAGVDFEFSYDTAYPTAIAIMAEDKALETMRFELVPKIITEENFWRNYFYRVSLIIQAAELGTLGADGVGQASSGEDANEVATKEKKSKTAEPAKGDSSVKAIAEQPKAVIEPEAQECDVQAAKSKAKAKAQAGKELGQKISESEFVSDDFQASSESDLAEIQDGMRKLGIDSMTQQALAATDE-EQWEKDLEAELKDYEVVDEGGTGGDGGGGRRKGRKAGEDDTEADEDEPTISNLRTRSTNNDWEEYADLIEDTDDLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:. : : * . . .. . . .* .. * * : : * .**. .*: .* :: *** .*:: *: : . :... : : *:**:..*:***: *:: * . ...**: :* .*:::**.** *:***:* *****:*:*.:* **.*:.:: **: *..*** ****::.** ********:*** *:*:* :*.*: ::.: **:**. : : .: *. : . **: * : : :*:. . . ****** *::.. : :::. *.:* :*. ::: . :: :***:*: **::**** * :.. :::*:: : : : . ", "identical_positions": 110, "similar_positions": 133, "identity": "19.86%" }, { "cls_id": "homologset.agr.FB:FBgn0013343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61265-1", "uniprot_id": "STX1B_RAT", "id": "P61265-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK---DSDDEEEV-VHVD-----RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDE--KTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGKLAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61266-1", "uniprot_id": "STX1B_HUMAN", "id": "P61266-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK---DSDDEEEV-VHVD-----RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDE--KTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGKLAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61264-1", "uniprot_id": "STX1B_MOUSE", "id": "P61264-1", "name": "Syntaxin-1B", "aln": "-MKDRTQELRSAK---DSDDEEEV-VHVD-----RDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDE--KTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGR-TTTNEELEDMLESGKLAIFTDDIKMDSQMT--KQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35526-1", "uniprot_id": "STX1A_MOUSE", "id": "O35526-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK---DSDDDDDVTVTVD-----RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDE--KTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGNPAIFASGIIMDSSIS--KQALSEIETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32851-1", "uniprot_id": "STX1A_RAT", "id": "P32851-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK---DSDDDDDVTVTVD-----RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDE--KTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGNPAIFASGIIMDSSIS--KQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16623-1", "uniprot_id": "STX1A_HUMAN", "id": "Q16623-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK---DSDDDDDVAVTVD-----RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDE--KTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGR-TTTSEELEDMLESGNPAIFASGIIMDSSIS--KQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "MTKDRLAALHAAQS--DDEEETEVAVNVDG----HDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDE--KTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGR-PTNDDELEKMLEEGNSSVFTQGIIMETQQA--KQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKIMILICLTVLGILAASYVSSYFM-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PT03-1", "uniprot_id": "A0A8M1PT03_DANRE", "id": "A0A8M1PT03-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRHGK---ELEEQNEVTMNNKM--VIEDGFMDEFFEQVEEIREFIDSLAEKVGEVKRNHSATLASPNPDE--KTKTEFEELMNDIKTLANKVRSRLQHIQQSIEHEEAFNGQSADVRIRKTQHSTLSRKFVEVMSEYNAAQSEYRERCKGRIQRQLEITGR-KTTKEELETILESDNPSIFTTGVFMDCSIT--KQAMNEIETRHNEIIQLESCIRELQDMFVDLAVLVENQGELINNIETNVSSAQEYVEKAKEETKAAIKIQKTSRTKLILIGGCVSVCVLILIIALIFGLT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q64704-1", "uniprot_id": "STX3_MOUSE", "id": "Q64704-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQL-TQDDDTDEVEIAID-----NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEP--KTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGNPAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIIIVVVVVLLGILALIIGLSVGLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08849-1", "uniprot_id": "STX3_RAT", "id": "Q08849-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQL-TQDDDTDEVEIAID-----NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEP--KTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGNPAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIIIVIVVVLLGILALIIGLSVGLK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13277-1", "uniprot_id": "STX3_HUMAN", "id": "Q13277-1", "name": "Syntaxin-3", "aln": "-MKDRLEQLKAKQL-TQDDDTDAVEIAID-----NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEP--KTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESGNPAIFTSGII-DSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00262-1", "uniprot_id": "STX2_MOUSE", "id": "Q00262-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRT-NDDGDT-AVVI-VE-----KDHFMDGFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEG--KIKEELEDLDKEIKKTANRIRGKLKSIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFISDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVAVAVIAVLALIIGLSVGK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50279-1", "uniprot_id": "STX2_RAT", "id": "P50279-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRK-SDDGDN-AVIITVE-----KDHFMDAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEG--KIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGR-TTTDEELEEMLESGKPSIFISDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVVVAVIAVLALIIGLTVGK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32856-1", "uniprot_id": "STX2_HUMAN", "id": "P32856-1", "name": "Syntaxin-2", "aln": "-MRDRLPDLTACRK-NDDGDT-VVVV--E-----KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEG--KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFTSDIISDSQIT--RQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEN6-1", "uniprot_id": "A0A8M2BEN6_DANRE", "id": "A0A8M2BEN6-1", "name": "", "aln": "-MRDRLADLNVGRH-NASEDG-GVAVSME-----RNDFMQDFFQKVEEVRRVIEKISSLVDEVKKKYSVILSAPNPDE--KTKEELEQLTVEIKKHANYVQKSLKSMHQSLPSDEQVNQASVDARIQKTQYTNLSHKFVEVMTQYNEAQVSFREKSKSRIQRQLEITGK-ITTNEELEEMLETGNPSIFTSDIISDSQIT--RQALNEIESRHQDILRLESSIKELHDMFVDMAMLVETQGEMIDNIEKNVHNAVEYVGQAKVETKKAVRYQTRARR-KWVYGAICGAVCIIILLLIIITAVYVD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P70452-1", "uniprot_id": "STX4_MOUSE", "id": "P70452-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDEDEVRVALVVHSGAARLGSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEE--SMKQGLQNLREEIKQLGREVRAQLKAIEPQK-EEADENYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKVMIAICVSVTVLILAVIIGITITVG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08850-1", "uniprot_id": "STX4_RAT", "id": "Q08850-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDEDEVRVALVVHSGAARLSSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEE--SMKQGLQNLREEIKQLGREVRAQLKAIEPQK-EEADENYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKVMIAICVSVTVLILAVIIGITITVG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12846-1", "uniprot_id": "STX4_HUMAN", "id": "Q12846-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEE--SMKQELQNLRDEIKQLGREIRLQLKAIEPQK-EEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVT--RQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39926-1", "uniprot_id": "SSO2_YEAST", "id": "P39926-1", "name": "Protein SSO2", "aln": "--MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVSEEQEMELRRSLDDYISQATDLQYQLKADIKDAQRDGLHDSNKQAQAENCRQK----------FLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "--MSYNNPYQLETPFEESYELDE--GSSAIG-AEG-HDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTNKQAQAENSRQR----------FLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: :: . : : : . *: : : ::: : . :: :: . : : : * : *:. : . . : :::. : :** * . .: : : . :* : : :: ::. **.:: :** : ** ::* : * * * :: *: :: : * . ... *:. :* : : ", "identical_positions": 22, "similar_positions": 76, "identity": "7.17%" }, { "cls_id": "homologset.agr.FB:FBgn0013347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZM7-1", "uniprot_id": "T2AG_MOUSE", "id": "Q80ZM7-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREVT--------ELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08950-1", "uniprot_id": "T2AG_RAT", "id": "O08950-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREVT--------ELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52657-1", "uniprot_id": "T2AG_HUMAN", "id": "P52657-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINAALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREVT--------ELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52656-1", "uniprot_id": "T2AG_DROME", "id": "P52656-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MS----YQLYRNTTLGNTLQESLDELIQYGQITPGLAFKVLLQFDKSINNALNQRVKARVTFKAGKLNTYRFCDNVWTLMLN------DVEFREVH--------EIVKVDKVKIVACDGK-SGEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32774-1", "uniprot_id": "T2AG_YEAST", "id": "P32774-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETFDKVVAETLKDNTQSKLTVK-GNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDSQSVISVDKLRIVACNSKKSE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:***.:*:**:* ::** **. :* . **::** *** : :* :..: ::..: *.*:** ***:***:::: : ..*:. .::.***::****:.* : ", "identical_positions": 41, "similar_positions": 45, "identity": "32.03%" }, { "cls_id": "homologset.agr.FB:FBgn0013432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYM7-1", "uniprot_id": "D3ZYM7_RAT", "id": "D3ZYM7-1", "name": "", "aln": "---MAASSRAQVLDLYRAMMRESKHFSAYNYRMYAVRRIRDAFRENKNVKDPVEIQALVNKAKRDLEIIRRQVLIGQLYSTDKLIIENQENPRT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K215-1", "uniprot_id": "LYRM4_MOUSE", "id": "Q8K215-1", "name": "LYR motif-containing protein 4", "aln": "---MAASSRAQVLDLYRAMMRESKHFSAYNYRMYAVRRIRDAFRENKNVKDPVEIQALVNKAKRDLEIIRRQVHIGQLYSTDKLIIENQEKPRT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD34-1", "uniprot_id": "LYRM4_HUMAN", "id": "Q9HD34-1", "name": "LYR motif-containing protein 4", "aln": "---MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIENRDMPRT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46098-1", "uniprot_id": "LYRM4_DROME", "id": "O46098-1", "name": "LYR motif-containing protein 4 homolog", "aln": "-----MSTRRQAITLYRNLLRESEKLPSYNFRMYAARKIRDTFRANRSTRDFAEIDRQMAEGQQNLELIRRQVIIGHLYSADKLVIENKKTLKPSDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B8JLQ0-1", "uniprot_id": "LYRM4_DANRE", "id": "B8JLQ0-1", "name": "LYR motif-containing protein 4", "aln": "---MASCSRAQVISLYRMLMKESKKFPSYNYRTYALRRVKDGFRENLHVDNPRTLDLLINQARENLAVIKRQVSIGHLYSAQRTVVEKEPHL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6Q560-1", "uniprot_id": "ISD11_YEAST", "id": "Q6Q560-1", "name": "Protein ISD11", "aln": "MPGFTAPTRRQVLSLYKEFIKNANQFNNYNFREYFLSKTRTTFRKNMNQQDPKVLMNLFKEAKNDLGVLKRQSVISQMYTFDRLVVEPLQGRKH---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.: **: :::::::: **:* * : : ** * : : . :.:.:* :::** *.::*: :: ::* ", "identical_positions": 17, "similar_positions": 34, "identity": "17.53%" }, { "cls_id": "homologset.agr.FB:FBgn0013435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15131-1", "uniprot_id": "CDK10_HUMAN", "id": "Q15131-1", "name": "Cyclin-dependent kinase 10", "aln": "-------------MAEPDLECEQIRLKCIRKEGF-FTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQS------------KRCKP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UMM4-1", "uniprot_id": "CDK10_MOUSE", "id": "Q3UMM4-1", "name": "Cyclin-dependent kinase 10", "aln": "-------------MAEVDLESDQIRLKCIRKEGF-FTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATSGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAAAEGQS------------KRCRP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KM47-1", "uniprot_id": "CDK10_RAT", "id": "Q4KM47-1", "name": "Cyclin-dependent kinase 10", "aln": "-------------MSQCQIWVR-HHLCCSFQIPT-LAAS-LFQLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCILLQVLRGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAATEGQS------------KRCRP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z840-1", "uniprot_id": "A1Z840_DROME", "id": "A1Z840-1", "name": "", "aln": "MSSLKSNDVDTNPAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYFVDPPQACDPGMMPTFPQHRNNAAPAPAVQPPADIPISDLLNVFIKRQRME", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : : :. . :****.*.*******:***:**********:::***********:****:***.**** :* : :* ***.*:*****: *:******.:*******:*:**. **:*::**** ****:.*:*** *:*****************:*.******* :. * *****::************* *:**::****.****.*** :*****.*** *:*:*::***:***.*****:.** . :::* :******. ** :.::* .**::**:*:**.***: :**:*.** : * .*:* :*****:***: *...: : : ** : ", "identical_positions": 212, "similar_positions": 92, "identity": "54.78%" }, { "cls_id": "homologset.agr.FB:FBgn0013469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NDX6-1", "uniprot_id": "ZN740_HUMAN", "id": "Q8NDX6-1", "name": "Zinc finger protein 740", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQASLLACEGLAGVSLVPTAASKKMMLSQIASKQAE---NGERAGSPDVLRCSSQ------------GHRKDSDKSRSRKDDDSLSEASHSK------------------------------------------------KTVKKVVVVEQNGSFQVKIPKNFVCEHCFGAFRSSYHLKRHILIHTGE----KPFECDICDMRFIQKYHLERHKR--VHSGEKPYQCERCHQCFSRTDRLLR---------------------------HKRMCQGCQSKTSD----GQFSL---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZQ6-1", "uniprot_id": "ZN740_MOUSE", "id": "Q6NZQ6-1", "name": "Zinc finger protein 740", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMLSQIASKQAE---NGERAGSPDVLRCSSQMDCKPRFDLSSKGHRKDSDKSRNRKEDDSLAEASHSK------------------------------------------------KTVKKVVVVEQNGSFQVKIPKNFICEHCFGAFRSSYHLKRHVLIHTGE----KPFECDVCDMRFIQKYHLERHKR--VHSGEKPYQCERCHQCFSRTDRLLR---------------------------HKRMCQGCQSKTSE----GQFSL---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWP1-1", "uniprot_id": "A0A8I5ZWP1_RAT", "id": "A0A8I5ZWP1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEASLLACEGLAGVSLVPTAASKKMMLSQIASKQAE---NGERAGSPDVLRCSSQ------------GHRKDSDKSRNRKDDDTLAEASHSK------------------------------------------------KTVKKVVVVEQNGSFQVKIPKNFICEHCFGAFRSSYHLKRHVLIHTGESAVFNTSLFTLVRNRLSVTYVICVSSRSTILNATSGYTVAKSLTSVNDVISVFLGQ------------------------TDYSDTNGCAKDASPRLLMGSFLYRQEGP----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PF84-1", "uniprot_id": "M9PF84_DROME", "id": "M9PF84-1", "name": "", "aln": "MTMAEGTDPMGHGHHTNPHNPPQQPPQHHPHHLPLPHPPPAPPPQLLNFNHHQQQYLPHMYPAAAAAAQSHSHYGGLQYPHPHALQHQHHPHQHQHHLPLALSLHQQAAAAAAVAAAVATNHSNNNNQASVANNNIVVPWKQRKRKRLSAVLDKLHHNNNNNNNNNNETHSNGMACKAEPMEMKGDLAEDAEQDEDHDGSVPDEEDDSVDQDGDAGKYIKSEQPVSEDEENEQEMDQDIEDISGEDLELSHSDDNDQDDSPRISMSPLQLQAAQSNLPQDQNQPMNKENPLHVDIKTEIPSPYDRYFPIPSPLFGYYLHTKYLNEVFRRRHDLYPSPLQHTPSSIASETETSPNAQERKSSSNHVLPHALLANNSPPPSLPSPPRSESSVTNNVATTTTSSTTKKRSSPKPKGKKGEKKPMPPPQERPLDLCMRNEVEPKKYKKSGSKSSLESRSAGMMPPPPALSAASSLESMSALSPASSSHSGHMPITSAATPNHQPPPNSPYANAMNAAHAAAAAAAAAMIKMEMPLHPLHHQQMHHSQVPTTTVGVPVIKGDVASPTTKETVAWRYNLDVSPVVEEMPPGSDVAYVCPTCGQMFSLHDRLAKHMASRHKSRNPANDIAKAYSCDVCRRSFARSDMLTRHMRLHTGV----KPYTCKVCGQVFSRSDHLSTHQR--THTGEKPYKCPQCPYAACRRDMITRHMRTHTRYDSRGGSREGREGREGREGKESRDSRRSNERIEEPNSPGSHSLLDMKMNMNMGMGMGLNMGLPMNPMSLLQEELLQKSQPGLTLGGPMPLVVKTESAXRCLYAAASRPFMTC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::. *: : : *. *.: :. :.:: * . :: : : : .. * : .*::. .:. . .*.* : *: * :* * *.**: :*** :. : : . : .* .. . * :. . : . . . . . *.. ", "identical_positions": 22, "similar_positions": 61, "identity": "2.67%" }, { "cls_id": "homologset.agr.FB:FBgn0013531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIE9-1", "uniprot_id": "MED20_RAT", "id": "Q5XIE9-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSVQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHT-PGAPTVFG--------------NRHDAVYGPAD---TMVQYMELFNKVRK--------------QQQVP-------VAGIR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0X0-1", "uniprot_id": "MED20_MOUSE", "id": "Q9R0X0-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSLQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHA-PGAPTVFG--------------NRHDAVYGPAD---TMIQYMELFNKIRK--------------QQQVP-------VAGIR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H944-1", "uniprot_id": "MED20_HUMAN", "id": "Q9H944-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGP----CLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGT-VTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHT-PGAPAVFG--------------NRHDAVYGPAD---TMVQYMELFNKIRK--------------QQQVP-------VAGIR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBX1-1", "uniprot_id": "MED20_DANRE", "id": "Q6DBX1-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTCVCQVPVAEGKSVQQTVDLLHRKLEQLGAVKQGNFWVDCETYHATGN---ATGQPSKLLYVMHNSEAPLSCMALFEGGP----GLSADANFDVLMIKLKSHFQNAKGHKVESRGTRYRYCDFLVKIGT-VAMSSSARGISVEVEYCACVIPGDCWNLMKEFMQSFLGSNT-PELPTVFT--------------NKAEGLYVPVDCMDTMSQYLELFSKVRK--------------QQVLP-------GSGVR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91641-1", "uniprot_id": "MED20_DROME", "id": "P91641-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGVTILQPYPLPEGKSGAHIIDQLSKRLLALGATHAGQFLVDCETFISTPQP--HNGAPGRAVHVLHNSEYPASTFSIIDNGTGKQVAIVADNIFDLLMLKMTNTFTSKKQTKIESRGARFEYGDFVIKLGS-VTMMEHFKGILIEIEYKSCVILAYCWEMIREMLQGFLGIAVNKDFPSYFAPQTIMTAMGQQQLHAKHNDIFEPMD---TVKQYLEQFTNYRKHVTLMGGMGSGPGSQQVGPNVHMSPAVAGLHRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34162-1", "uniprot_id": "MED20_YEAST", "id": "P34162-1", "name": "Mediator of RNA polymerase II transcription subunit 20", "aln": "MGKSAVIFVERATPATLTELKDALSNSILSVRDP----WSIDFRTYRCSIKN--LPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIA--GIEGHLAEIR----------AKEYKTSSDSLG-PDTSNEICDLAYQYVR--------------------------ALEL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : . : . : * . : : : :* .*: : . . .: :: : . . . : :... ** ::: . . . :.:: :. ::* .: :: : : : . . . .: : * . : . . . . * : : : : : ", "identical_positions": 10, "similar_positions": 67, "identity": "3.88%" }, { "cls_id": "homologset.agr.FB:FBgn0013548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZER4-1", "uniprot_id": "D3ZER4_RAT", "id": "D3ZER4-1", "name": "Denticleless protein homolog", "aln": "MTSVWRGVWRPGLAVAGVGGKTVSRCGGRKRRLRRNLGAISSAFSSAESSPQDEMLFNSVLRQPQLGVLRNGWSSHYPLQSLLSGYRCSCNDEHTSYGETGVPVPPFGCTFCTAPSMEHILAVANEEGFVRLYNTESQTS--KKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAG--ELMGTCKGHQCSLKSVAFSKFQKAVFCTGGRDGNIMIWDTRCNKKDGFYRQVNQISGAHNTADKQTPSKPKKKQNSKGLAPSVDSQQSVTVVLFQDENTVVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGTSTRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKTSPLAVFNGHQNSTFYVKSSLSPDDQFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE-EKPEGDKHSIVGWTSQKKKEVKAGPVSAP-------NSLSTPAKAPRSQCSPSASSPSSAR-TPSCAGDLPLP--SNTSTFSVKTTPVTTRSPVSRRGSSSSVSPKPPSSFKMSLRNWVTRTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVESLHLD---LCCLSGTQEVLSQDSAGPTKSSKTEGTGTSISEPPSPVSPFASEGCGPLPLPLGPCGEGSEMVGKENSSPEN-------KNWLLAMAAKHKAENSSPRSPSSQTPSSRRQSRKTSPGPVTITPNSMRKICTYFRRKTQDDFCSPEHSTEL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLR7-1", "uniprot_id": "DTL_MOUSE", "id": "Q3TLR7-1", "name": "Denticleless protein homolog", "aln": "------------------------------------------------------MLFNSVLRQPQLGVLRNGWSSHYPLQSLLSGYQCNCNDEHTSYGETGVPVPPFGCTFCTAPSMEHILAVANEEGFVRLYNTESQTS--KKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVRAG--ELMGTCKGHQCSLKSVAFPKFQKAVFSTGGRDGNIMIWDTRCNKKDGFYRQVNQISGAHNTADKQTPSKPKKKQNSKGLAPAVDSQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGTSTRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKTSPVAVFNGHQNSTFYVKSSLSPDDQFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE-EKP-GDKHSIVGWTSQKKKEVKACPVTVP-------SSQSTPAKAPRAKSSPSISSPSSAACTPSCAGDLPLP--SSTPTFSVKTTPATTRSSVSRRGSISSVSPKPLSSFKMSLRNWVTRTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQAESLRLD---LCCLSGTQEVLSQDSEGPTKSSKTEGAGTSISEPPSPVSPYASEGCGPLPLPLRPCGEGSEMVGKENSSPEN-------KNWLLAIAAKRKAENSSPRSPSSQTPSSRRQSGKTSPGPVTITPSSMRKICTYFRRKTQDDFCSPEHSTEL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ0-1", "uniprot_id": "DTL_HUMAN", "id": "Q9NZJ0-1", "name": "Denticleless protein homolog", "aln": "------------------------------------------------------MLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSF--RKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAG--ELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE-EKPGGDKLSTVGWASQKKKESRPGLVTVT-------SSQSTPAKAPRAKCNPSNSSPSSAACAPSCAGDLPLP--SNTPTFSIKTSPAKARSPINRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQAEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLD---LCCLAGNQEDLSKDSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPEN-------KNWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKKLPSPVTITPSSMRKICTYFHRKSQEDFCGPEHSTEL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHI5-1", "uniprot_id": "DTL_DANRE", "id": "Q5RHI5-1", "name": "Denticleless protein homolog", "aln": "-----------------------------------------------------MTLFHHVVDRGAKKRGRNGEQRLFPLSSLLDGYECARRDEHISYGASAAAVPPFGCTFSSAHGQQNCLAVANEEGFVTIFNTGEK----QSSVLKEWQAHDNAVFDIAWVPGTNCLVTASGDQTARLWDVITG--DLLGTFKGHQCSLKSVAFYKQEKAVFSTGGRDGNIMIWDTRCSKKDGFYRQVKQISGAHMKPERFTPQTKKRR----GMAPPVDSQQGVTVVLFCDETKLISSGAVDGIIKMWDLRRNYTAYHQNPLPLQAYPYPGSCTRKLGYSGLSLDYTGSRLFSNCTDDNIYMFNISGLKTTPVAVFSGHSNSSFYVKSTVSPDDQFLASGSSDHNVYIWKISDPKQAPMMLQGHSQEVTSVAWCPTDFTKIASCSDDNTVRIWRLNRKPEGENSTIQDGNLVGWTIRKVQSPNRTPGHHS-------PVELTPSKNPGSVRSVSLASPQPATCAPTGA-ALPLP--SNTS----SAPPAKLTS------------PKMPS----SLQQWISRS-SKSP-------------VRKALTPVLQGLS-------FEHRVKRRLETG--DSASSGLGEEIDGVSELYPNVKRSRSS---VSTLK------KEDSFG-LESEKRLGS------------------------------DGAEASGKENSSPRR-------TDWLSVISQKFKG-SAQPKSPSS---GSSQQDTRTLESPAAVSPRPMKVFSPPTNKKASPSKPMKKISSYFMKRTQD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24371-1", "uniprot_id": "L2DTL_DROME", "id": "Q24371-1", "name": "Protein lethal(2)denticleless", "aln": "-----------------------------------------------------MNIYNKLRAREHGYGNERTYDFALRRLSVAKEDSWRGIAPANYCPDFNPEPPIFSAKFANCDGYRHILAIANEDGKITLQDTTQRNHQPEEQSLVGPQCHFNAVFDLEWAPGQMRFVSASGDHTARLWEVAGSGIRGLNSYVGHTRSVKSAAFKRTDPAVFATGGRDGAILIWDIRANLNMDLTSRVDNCIYSGHTGGPGTPVSQRKQRTRTPKMAGGTTSSSITGLAFQDNDTLISCGAGDGVIKVWDLRRNYTAYKKEPLPRHKLPYAGSSTFRG-FTNLIVDASGTRLYANCMDNTIYCYNLASYSQRPLACYKGLLNSTFYIKSCLSPDGKYLLSGSSDERAYIWNLDHAEEPLVALAGHTVEVTCVAWGSSHDCPIVTCSDDARHKIWRIGPDLDGLSEAERAEKYRGTASYVREFGKKAFGPSSGNHKYNLRDLESTPRSLKRLMDQNERTPGSVEKTTTKRSFLEMLGVAGQETEATEQPQKRAKPLESRGRRLFGPSSQETACRHIQLQSINEEDASPSKRQKENSAAEDVSPLHKLLSTPSHSPLSENVNHVYTSPPTTSAAAAAVAADALNPPPISAAIYSPTSNLPNYVLDGEAPHLGIMSPKRKAKEKVDWLTNIRKQKLMSGRAHVTLSEKISEEQQADVLASPRLQSLRQSECSPRIHASPRRRISHTDGGGGTPAGSSSHSHSQSQPKTPTSSRRNSETTLLRFFSIQRSSSVPAEETTTTNAAPSSSDPHPPAVTAPAATPLSMRTPTTAVGSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : : .. . *: * *...*... . .: **:***:* : : :* .: .. : .* *****: *.** :*:*:**:**::*:* . :.: ** *:**.** : : ***.****** *::** *.. : .: :*.: : . ** . ::: . ...:* : * *: .::*.** **:**:****:*****:::*:. : *.*:.* : ::.* :* :*: *::** *:.** :*::. . *:* :.* **:**:** :***.::* *****. .***::. . .. * **: ***.*.* .:. *.:**** :***:. : . . * : : . . :..: . . :* .. :.: * : :. . . . .: : .::. . * * :* * . : . :. : : . : . ::. . . : :* : ::**.. . . : . . ...*::*:* .* : : : . . . .:. :. ", "identical_positions": 135, "similar_positions": 209, "identity": "16.4%" }, { "cls_id": "homologset.agr.FB:FBgn0013563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZB2-1", "uniprot_id": "D3ZZB2_RAT", "id": "D3ZZB2-1", "name": "Peroxisomal ATPase PEX1", "aln": "MWSSDRLAGAGS---GGAVVTVAFTNARDCFLHLPRHLVAQLHLLQNQAIEVTGDHQPTYLSWVEGRHFNDQSENVAEINRQVGQKLGLSSGD---QVFLRPCSHVVSCQQVEVEPLSADDWEILELHAISLEE-HLLDQIRIVFPKAIVPIWVDQQTYIFIQIVALMPTAPYGRLETNTKLLIQPKTRQAKESTFPKEGDARGQAHNYGREQKGTVKELQTKQLHKNTEAVPVSNGRNPEVPGDS-VKPRWWAVLGSMFSFGPDNKQESAWGSLELGAFKNMQSQTVPLDSIFRVCQVQPPSVHNTPANSVFHKHCTVHVFPWDQEYFDVEPSFTVVYGKLVKLHSPKQQQDKSKQGVLLPEKEKQLSQSPGHKRIGSDGSEEAAETCVLKVVWNGLEELKNATEFTKSLEPLHHGKVWIPADLRKRLNIEMHAVVRITPLETTPVIPRALRLQPAENLPRDVSEEEVKAVFSSWLQESATTMFPLIISKQECIKLEIKDGLKEFSLSIVHSQEKEKEQGRTVFVLSPILLQKISVQVLLEPMIG-EHSEEIDILLPSLTLSSLGGVSSLSVSAMEHITHSLLGRP-LSRQLMALVAGLRNGALLITGGKGSGKSTLAKAICKEAHDALD-AHVEMVDCKALRGKR-LESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPSTPEHEHSPEAVQSQR---LAHALNNMIKEFVSMGSLVALIATSQLQHSLHPSLVSAQGVHTFQCIQHIQPPDQEQRCEILHSVVKNKLGCDISKSPDLDLKCIAKETEAFVARDFTVLVDRAIHSSLSRQQNP---TREGLTLTTADFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIQGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKS---------LPLADDVDLQHVASVTESFTGADLKALLYNAQLEALQGRLLPGGLHDGGSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGASCDLSSHCLSAPSSMTQDLPATPGKDPLFTQHPVFRTPSQEGSQDLTQEQRDQLRADISIIKGRYQSQSGEDESLNQPGPIKTSFAISQAHLMTALAHTRPSINEDEGKEFAELYENFQNPKK-RKNQSGTVFRTGQKVTLNFVLTPHFTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BL07-1", "uniprot_id": "PEX1_MOUSE", "id": "Q5BL07-1", "name": "Peroxisomal ATPase PEX1", "aln": "MWSSDRLAGAGS---GGAVVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVASDHQPTYLSWVEGRHFNDQSENVAEINRQVGQKLGLSSGD---QVFLRPCSHVVSCQQVEVEPLSADDWEILELHAISLEQ-HLLDQIRIVFPKAVVPIWVDQQTYIFIQIVTLMPAAPYGRLETNTKLLIQPKTRQAKESTFPKEGDAHGQVHSYGREQKGLSKELQTRQLHTNSEGITASNGRDPKVPGGP-LKPSWWAVLGSMLSFGPDSKQESAWGSLELGAFKNMQSQAAPLEGTFRVCQVQPPSARTTTATSVFHKHCTAHVFPWDQEYFDVEPSFTVTYGKLVKLHSPKQQQDKSKQGVLLPDKEKQLSKSPDHKQISSNRSEEAAEACVLKVVWNGLEELKNATEFTESLELLHRGKVWIPDDLRKRLNIEMHAVVRITPLETTPKIPRSLKLQPRENLPKDVNEETIKTVFSSWVQQSATTMLPLVISKEERIKLEIKDGLREFSLSTVHSQEKEKEEGKTVFVLSSILLQKISVQVLLEPMIKEEQSAEIDFLLPSLTLSSLGGVSALGASAMEHITHSLLGRP-LSRQLMALVAGLRNGALLITGGKGSGKSTFAKAICKEAQDTLD-ARVETVDCKALRGKR-LESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPSVPEQEHSPEAVQSQR---LAHALNDMIKEFVSTGSLVALIATSQLQQSLHPSLVSAQGIHTFQCVQHLQPPNPEQRCEILHSVVKNKLGCDISNFPDLDLQCIAKDTEAFVARDFTVLVDRAIHSSLSRQHSS---SREDLTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKS---------LALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQGRLLPSGLPDGGSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLEQSLLSLEMSEILPDESKFNMYRLYFGSSYESELGNGTPSDLSSHCLSAPSSVTQDLPAAPGKDPLFTQHPVFRTPSQEGCQDLTQEQRDQLRAEISIIKGRYRSQSGEDESLNQPGPIKTTFAISQAHLMTALAHTRPSISEDEGKEFAELYENFQNPKK-RKNQSGTVFRTGQKVTLA---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43933-1", "uniprot_id": "PEX1_HUMAN", "id": "O43933-1", "name": "Peroxisomal ATPase PEX1", "aln": "MWGSDRLAGAGG---GGAAVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVVWSHQPAFLSWVEGRHFSDQGENVAEINRQVGQKLGLSNGG---QVFLKPCSHVVSCQQVEVEPLSADDWEILELHAVSLEQ-HLLDQIRIVFPKAIFPVWVDQQTYIFIQIVALIPAASYGRLETDTKLLIQPKTRRAKENTFSKADAEYKKLHSYGRDQKGMMKELQTKQLQSNTVGITESNENESEIPVDSSSVASLWTMIGSIFSFQSEKKQETSWGLTEINAFKNMQSKVVPLDNIFRVCKSQPPSIYNASATSVFHKHCAIHVFPWDQEYFDVEPSFTVTYGKLVKLLSPKQQQSKTKQNVLSPEKEKQMSEPLDQKKIRSDHNEEDEKACVLQVVWNGLEELNNAIKYTKNVEVLHLGKVWIPDDLRKRLNIEMHAVVRITPVEVTPKIPRSLKLQPRENLPKDISEEDIKTVFYSWLQQSTTTMLPLVISEEEFIKLETKDGLKEFSLSIVHSWEKEKD--KNIFLLSPNLLQKTTIQVLLDPMVKEENSEEIDFILPFLKLSSLGGVNSLGVSSLEHITHSLLGRP-LSRQLMSLVAGLRNGALLLTGGKGSGKSTLAKAICKEAFDKLD-AHVERVDCKALRGKR-LENIQKTLEVAFSEAVWMQPSVVLLDDLDLIAGLPAVPEHEHSPDAVQSQR---LAHALNDMIKEFISMGSLVALIATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCDINKFTDLDLQHVAKETGGFVARDFTVLVDRAIHSRLSRQSIS---TREKLVLTTLDFQKALRGFLPASLRSVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILNVLSDS---------LPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGTSSDLSSQCLSAPSSMTQDLPGVPGKDQLFSQPPVLRTASQEGCQELTQEQRDQLRADISIIKGRYRSQSGEDESMNQPGPIKTRLAISQSHLMTALGHTRPSISEDDWKNFAELYESFQNPKR-RKNQSGTMFRPGQKVTLA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUC7-1", "uniprot_id": "Q9VUC7_DROME", "id": "Q9VUC7-1", "name": "Peroxisomal ATPase PEX1", "aln": "-----------M---FKRTFKVVYRPIRSNFVLLPDQYYGVVSTYDTGCLSLQYNGRTHYASWAPQKGGGGIKDTEIGINARAAKEIGLHEND---LVKCALIADVLNLRSVHVTPVSSKDWEIIELSTEKISG-SVLEQTRIVNSTQILIVWINKSMQVALTVDRLKPHMNYGRIDHNTELVVAPNLYKGLTNGTSN-GVIEENTKLSRSKTTAQVKDELTEKLTPLTHSSTVSNVKNTIQRNKR---------QDHMERLKKDLRRESSR-SFEFRVIRGLWREQAQESDVFVNGKHLP-------------------------EFFDLD--------LFYCMHTAADKDYYVRVRTVEDDIEDDLPETIHP-------------------------------------------SIELNANLMKLLGIKELERVVLRPKTTVVNFVEKIELFANKKTHYKIMENAFKRFVIERTQH-----KPMLFNQEEVVRLED-----DLLVTVGILPEHFRYCVVDAQFLKESKIYAADLVRPVGEIIKEETPP----------TSPLSVQDLIQLPEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRSKGRK-TESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGE---QSSQDGEYYNR---MADTVYQLIVQYTTN-NAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILR-----ELCSHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSST---------LSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEALAQFGHEK--------------------------------------------------------------------------------------------------------------------------------------------------------LAKKISLKQKHLIESFQTTRPSLSASDVAKYHRTYARFTNKEK-TSR-----EFVAKRATLA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24004-1", "uniprot_id": "PEX1_YEAST", "id": "P24004-1", "name": "Peroxisomal ATPase PEX1", "aln": "MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQEFGIAVHSHNSDIPIVHLGWDG--HDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYDHTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEG-IVTKFKIDRVEPSMKSARITDGSLVVVAPKVNKTRL-----------VKAEYGHSNKTILKNGAIQLLKKVILRSTVCKMDFPKD-----------NLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIG---------------------------------------VFIKCDSQIPENHIALSSHLWDAFFTHP----------------------------------------------------MNGAKIKLEFLQMNQANIISGRNATVNIK-----YFGKDVPTKSGDQYSKLLGGSLLTNN-------LILPTEQIIIEIKKGESEQQLCNLNEISNESVQWKVTQMGKEEVKDIIERHLPKHYHVKETGEVS---------RTSKDEDDFITVNSIKKEMVNYLTSP-----------IIATPAIILDGKQGIGKTRLLKELINEVEKDHH-IFVKYADCETLHETSNLDKTQKLIMEWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFNKDNKRIRVLFSGKQKTQINPLLFD---KHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKLN--RDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDN-------VVTRELFSKSLSAFTPSALRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRLDKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQGLCYNAYLKSVHRWLSAADQSE-----------------------------------------------------------------------------------------------------------VVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVHETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNGENSIDIGSRLSLM---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :: : : . . . .* .. :. ** . .* . . : .. .* * * ::.****:: : :. :*.* *** . . ::: : : : * .*: .: ::: *: : . . *: . * . .: . : :.. :: . .. : : : :: : . : * :: : .. : :. . :: * . . . :: * : :* : : .: . . : :. . . : .: . : : ::: * .* **: : : : .: . .: . . : :. ** : : . *::::*:::: : . : * :. : : : :: : . . : :: : : :: * . * .. : : * :* : .:. **:: .: * .: *: :.:: :. : .. : * : . :: .: .* .. :* :.: *::* :* *:* ::*:**** ** *** *.. :* . :.:**::***:* *:** **: :*::* **::.:**:******:*:**:****.*************::**.***:** ::******:*:*.****.**:*: * * * *: *: .: .: :.* . .*:. .* * .::***::.: .* : ::: * . . :. .*: : *:**:. .: : * * : .. ..: :* ", "identical_positions": 148, "similar_positions": 287, "identity": "11.21%" }, { "cls_id": "homologset.agr.FB:FBgn0013576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ38-1", "uniprot_id": "D3ZQ38_RAT", "id": "D3ZQ38-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGRQWR------------------------------------YTQLP-----TEMEDTLSGEEG--------------------------------------------------------EEEEEEE----PAPAPQD--PVEPQLTEASQVLGASEIKQLSLHLPPRVTGH-PWNLIFCTSRDGFSLQRLYRQMEGHSG-----PVLLLLRDQDGQMFGAFSSSALRLSKG--FYGTGETFLFSFSPQ-----------------------------LKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARR-EQFCIRELEAWALS-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ACG1-1", "uniprot_id": "TLDC2_MOUSE", "id": "A2ACG1-1", "name": "TLD domain-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDTLSGEEG--------------------------------------------------------EEEEEEEPA--PAPAPQD--PVEPQLTEASQVLGASEIKQLSLHLPPRVTGH-PWSLVFCTSRDGFSLRRLYRQMEGHSG-----PVLLLLRDQDGQMFGAFSSSAIRLSKG--FYGTGETFLFSFSPQ-----------------------------LKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARR-EQFCIKELEAWVLS-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PJX2-1", "uniprot_id": "TLDC2_HUMAN", "id": "A0PJX2-1", "name": "TLD domain-containing protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRGLRWR------------------------------------YTRLP-----SQVEDTLSGEEGN-------------------------------------------------------EEEEEEEAAPDPAAAPED--PTVPQLTEASQVLSASEIRQLSFHFPPRVTGH-PWSLVFCTSRDGFSLQSLYRRMEGCSG-----PVLLVLRDQDGQIFGAFSSSAIRLSKG--FYGTGETFLFSFSPQ-----------------------------LKVFKWTGSNSFFVKGDLDSLMMGSGSGRFGLWLDGDLFRGGSSPCPTFNNEVLARQ-EQFCIQELEAWLLS-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KMM3-1", "uniprot_id": "OXR1_MOUSE", "id": "Q4KMM3-1", "name": "Oxidation resistance protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVSNLSWLKKKS-QSVDITAPGFNPLGGAGKQAPQASKPPAPKTPIIEEEQNNSANTQKHPS------RKSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKG-----------------------------------------TIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESS-----------PSLSPVSPLSPTSSEAEFDKTTTPDVAHPKEAPPAS-TVSGIRPARVVSSTSEEEEAFTEKFLKINCKYITIGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKE-------------------------------------------------------SLPIEL--------------DQLSGRGSCHSKKATGVSAEDADPRAR--------------------------------------DQGND----------------SASTAPRSTEES--------LSEDAFTESELSPIREELLSS-EPRQE-KSSDASS-----ESVQTVSQMEVQSLTATS----------EAANVPDRTSSNPG-------ALSHETGLSGLETATKGGDKATESLQEVSGPKEQSTEVKGQDNQDSSHQ----------------------------------------ESSLQQEAGE-DSVSSGETVELKEKPAVLKDQQGQELKRDSETEVEELRKLWKTHSMQQAKQQRDTIQQVSQRESKHSS--------------------------AAADAHGEGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDSGEYTREPGFIVVKKMDESEANEAP-A------------GEAAAREWEVVSV--AEYHRRIDALNTEELRTLCRRLQITTREDINSKQVAPAKADLEPE--SFRPNLSDPSELLLPDQIEKLTKHLPPRTIGY-PWTLVYGTGKHGTSLKTLYRTMTGLDT-----PVLMVIKDSDGQVFGALASEPFKVSDG--FYGTGETFVFTFCPE-----------------------------FEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKK-EDFFIQDIEIWAFE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8B0-1", "uniprot_id": "OXR1_RAT", "id": "Q4V8B0-1", "name": "Oxidation resistance protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYLTTFTGKSGRLLRGTASRLWGLGGGG-EARQVRFEDYLREPAPGD-PGCGPGELRPPS------PTSPEG----PDTGQKKTLDKKDGRRMSFQKPKG-----------------------------------------TIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESS-----------PSLSPVSPLSPTSSEAEFDKTTTPDVVHPKEAPPSS-TESSIRPARVVSSTSEEEEAFTEKFLKINCKYITNGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKLKE-------------------------------------------------------SLPIEV--------------DQLSGRGFCHSKKMTGVPAEETDSRSR--------------------------------------DQGND----------------SVSTAPRSTEES--------LSEDVFTESELSPIREELPSS-ELRQE-KSSDASS-----ESVQTVSQIEVESLTAAS----------ESADVPDHTNANSGRSSSEVGALSHETGLSSLEIATKEGDKATGNLQEVSGPKEQSTDIKGQDNQDSFHH----------------------------------------ENSLQQEAGE-DSLSSGETVELTEKPTVLKDQQGKELKRDSETEVEELRKLWKTHSMQQAKQQRDTIQQVAQRESKHRG--------------------------APADAHGEGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKMAESGPDEAP-A------------GEAAAREWEIT-----------------------------TREDINSKQAAPAKADLEPE--SFRPNLSDPSELLLPDQIEKLTKHLPPRTIGY-PWTLVYGTGKHGTSLKTLYRTMTGLDT-----PVLMVIKDSDGQVFGALASEPFKVSDG--FYGTGETFVFTFCPE-----------------------------FEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKK-EDFFIQDIEIWAFE-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N573-1", "uniprot_id": "OXR1_HUMAN", "id": "Q8N573-1", "name": "Oxidation resistance protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKDKNSPGLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKHPS------RRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKG-----------------------------------------TIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESS-----------PSLSPVSPLSPTSSEAEFDKTTNPD-VHPTEATPSS-TFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKE-------------------------------------------------------SLPIDI--------------DQLSGRDFCHSKKMTGSNTEEIDSRIR--------------------------------------DAGND----------------SASTAPRSTEES--------LSEDVFTESELSPIREELVSSDELRQD-KSSGASS-----ESVQTVNQAEVESLTVKS----------ESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKE-DQIADNFQGISGPKEDSTSIKGNSDQDSFLH----------------------------------------ENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKI--------------------------TSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDS-S------------NQAAAREWEVVSV--AEYHRRIDALNTEELRTLCRRLQITTREDINSKQVATVKADLESE--SFRPNLSDPSELLLPDQIEKLTKHLPPRTIGY-PWTLVYGTGKHGTSLKTLYRTMTGLDT-----PVLMVIKDSDGQVFGALASEPLKVSDG--FYGTGETFVFTFCPE-----------------------------FEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKK-EDFFIQDIEIWAFE-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PD70-1", "uniprot_id": "OXR1A_DANRE", "id": "A0A8M9PD70-1", "name": "Oxidation resistance protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPLQHTPRLKKKSQSVDIGSQGFPARLIPSLSLNRSS-PPAAKTNTSEVQENNTTNAQRRVP------RCSDLKRGYTIDTGQKKTPEKKDGRRMSFQRPKG-----------------------------------------TIEYSVESRDTLNNIALKFDTTPNELVQLNKLFSRNVVPGQVLYVPDPEYVSSAGSS-----------PSFSPSSPLSPTSSEADLEKVTTDSNGPPRSDAPAPPVLSALRSSRVVSSTSEEEEALTEKFLKINCKYITDGKGVVSGVLLVTPNNIMFDPHRTDPLVLEKGCEEYGIMCPLEEVQSAAVYKEIIDSKIRD-------------------------------------------------------SVTDLE--------------AVFS-----------------SFSHQT--------------------------------------DQRYD----------------SASTAPRSTEGS--------FSEDVFTESELSPIREEHQSTEELQQEDKSSGASS-----QSVKTLLQ-EPQSHTEEK----------DNDGEPAG---------------------------------------DTAKPIQD--EPTSRDHQQTPHC----------------------------------------QTEGEPAAQE----SSAEGVKLT-----------RDGTRDSETDVEELRKMCKTHTMQQAKEQRESVQQAQRESEQQTT--------------------------EQSQRLSSAEGPVVSKERQKSHKFLCLRVGKAMKKTFVSNASASMQQYAQRDRKHEYWFAVPQERSDHLYVFFIQWSPDVFGDGLGSISRDPGFIVVKKIEESEANEEQQP------------EENSEKEWEVVSW--TEYHRRIDALNSEDLRSLCKRLQITTKEDVNSKHGTSITASLEPE--TFKPNLNEPSDLLEAEQIEKLAKHLPPRTIGY-PWNLAFSTSKHGMSIKTLYRAMQDQDS-----PMLLVIKDSDGQIFGALASEPFKVSEG--FYGTGETFLFTFYPE-----------------------------FEAYKWTGDNLFFIKGDMDSLAFGGGSGEFGLWLDGDLYHGRNHSCKTFGNPMLSMK-EDFFVQDIEIWSFE-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DFV7-1", "uniprot_id": "NCOA7_MOUSE", "id": "Q6DFV7-1", "name": "Nuclear receptor coactivator 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIVSAASSKSRSGKDDANSDILEQDKFNVTAEGDHSTDDKKKRKSNQLKEIRRTELKRYYSVDDNQNKTHDKKE-KKMMVQKPQG-----------------------------------------TMEYTAGSQDTLNSVALKFNVTPNKLVELNKLFTHTIVPGQVLFVPDANISSSTIQL-----------SSSTPGATVSPSSSDAEYDKLPDADLARKALKPIER----------VLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYSDISHMKIKD-------------------------------------------------------ALPSDLPRDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDAKSVRSPEESTERTCTRIEPPDNSELWKLKNLQSSRG----------------TTSESPSVTQLS-----MRAALEPTAKENCLLKGDEDFVDLEELSSQPESGINKG-----DATKECLSYD---QKKDGPHTVMSAKKGHVQSAQEVMGPESDTELKGALDLETAEKQDEAPEVDKHSGSPENLGESTLNIHEDLDKIKLIEFYLNKNK----------------------------------------EGSQLLENVQKSELSDRKSIEPGGIDITLSSSLPQAGDSPPEDNKEPGTLWVKGGETLPLKLDPSAEETVINNKEVLDS-LGSSLDKMCHSAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTATMVQQYSKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYG----KDAKEQGFVVVEKEE--LNMIDNFF------------SEPTTKSWEIIT-----------------------------VEEAKRRKSTCSYYEEEEEEEEGLPILQPHSALLENMHIEQLARRLPARVQGY-PWRLAYSTLEHGTSLKTLYRKSASLDS-----PVLLVIKDMDNQIFGAYATHPFKFSDH--YYGTGETFLYTFSPN-----------------------------FKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLEVWTFE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWN1-1", "uniprot_id": "F1LWN1_RAT", "id": "F1LWN1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTKEEKKEPKERKQSYFARLKKKKQAKQNAEIVSAARSHS--GKDDSHSVILEQDKSNIAAEGDQSTDEKKKRKNNQLKEIRRMELKRYYNADDNQSKSHDKKE-KKMVVQKPQG-----------------------------------------TLEYTAGSQDTLNSVALKFNVTPNRLVELNKLFTHTIVPGQVLFVPDANIPSSTLRL-----------SSSTPGATVSPSSSDAEYDKLPDADLARKALKPIER----------VLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKD-------------------------------------------------------ALPSDLPRDVCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLALDVKSVGSPEESTERMRTRTEPPDDSESWKLKNLEYSRG----------------TASEFPSVTQLSKGPSSVCAALEPTAKENRLL-GDEDFVDLEELSSQPGSGMDKG-----DARKECLPYD---QKKDAPQTIMSAKKGEEQSAPDVTGTESDAELKGALDSETGEKQDEAPEVDKQSGSPENWRESTLSIHEDLDKVKLIEFYLNKNK----------------------------------------EGSQLSENVLKSELSERKSIEPDGIDITLSSSLPQAGDSPPESHKEPGTLCVKGGGTPPPKLHPSAEETVTNNKEALDS-LESSLDKLCQGAQMDNRSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHSTTMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYG----KDAKEQGFVVVEKEE--LTMIDNFF------------SEPTTKSWEIIT-----------------------------VEEAKRRKSTCSYYEEEEEEEEGLPILQSHSALLENMHIEQLARRLPARVQGY-PWRLAYSTLEHGTSLKTLYRKSASLDS-----PVLLVIKDMDNQIFGAYATHPFRFSDH--YYGTGETFLYTFSPN-----------------------------FKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLESIITAQTDPGRLPVEDRHRRQKSEVQIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NI08-1", "uniprot_id": "NCOA7_HUMAN", "id": "Q8NI08-1", "name": "Nuclear receptor coactivator 7", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTKEEKK---ERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKE-KKMVVQKPHG-----------------------------------------TMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRL-----------SSSSPGATVSPSSSDAEYDKLPDADLARKALKPIER----------VLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKD-------------------------------------------------------ALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTG--HTPTKPSGSSVSEKLKKLDSSRE----------------TSHGSPTVTKLSKEPSDTSSAFESTAKENFLG-EDDDFVDLEELSSQTGGGMHKK-----DTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNK----------------------------------------EGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVI--KEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYG----KDAKEQGFVVVEKEE--LNMIDNFF------------SEPTTKSWEIIT-----------------------------VEEAKRRKSTCSYYEDEDE--EVLPVLRPHSALLENMHIEQLARRLPARVQGY-PWRLAYSTLEHGTSLKTLYRKSASLDS-----PVLLVIKDMDNQIFGAYATHPFKFSDH--YYGTGETFLYTFSPH-----------------------------FKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLEVWAFD-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K620-1", "uniprot_id": "A0A0B4K620_DROME", "id": "A0A0B4K620-1", "name": "Oxidation resistance protein 1", "aln": "MSIIDSGKYRLRKDWASASIPSLVNIDEHDGDSGDTEGSLNATAPLPPQKPPRRSSLALGLFSSKSDKSQKRRSSIAVSFLRRDSSKNSTKDSYESAVRSEKSDGSGTPTSPEIVYSSEENIRASSPNDPGKQTFFEDGSQSPRPVLQGLNTSYEGPQNDRQRRRRSSLQTKLDRHRRKKMEYSNQRSLDSGMMCSESHSDLTNDSLAEGSGSFANRSRNGNDDEDDIIDPSHGEYFPREKRHSWWNIFVPDNFKNRSRRASQDVSSLSRSVDNLAIPVRRSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAARFDTTPSELTHLNRLNSSFIYPGQQLLVPDKSAKDDASSSSTHDADGASLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIERVGGSSQQQQAEEEANKSDDPVITQRFLKINVRHITDGQGVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLNSASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLCSSTGRDGDAFPKAFDRERVEDSSMEAKDSAKTDALDDEDKKAGLGLSSTRSTLEERRKSLLDHHWAIPSKDRSSEDEGDNESNVTVDSGARVQDPHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSGIDLEHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALAVTDKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLFSKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRSMVSMDDKPELFISVDKLIPRPARACLDPPLYLRLRMGKPIGKAIP--LPTSVMSYGKNKLRAEYWFSVPKNRVDELYRFINTWVKHLYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGY-SWSLIFSTSQHGFALNSLYRKMARLES-----PVLIVIEDTEHNVFGALTSCSLHVSDH--FYGTGESLLYKFNPS-----------------------------FKVFHWTGENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQ-EDFVIKTLECWAFV-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08952-1", "uniprot_id": "OXR1_YEAST", "id": "Q08952-1", "name": "Oxidation resistance protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGVKDAIFKIKRSIAGTDSSDSTAYTTAS---------------------------------------------ESSPQLKDSHNPFR-------------------------------------------------------NKTTSERTIVEEGSLPPVRLNGYLPSTKNKLLTPEMCDEIRTLMPTRIQLYTEWNLLYSLEQHGSSLHSLYSNVAPDSKEFRRVGYVLVIKDRKNGIFGAYSNEAFHPNEHRQYTGNGECFLWKLDKVPDVNISEKEESEQEGKEGKEEGDKEERWRFSGYPYTGVNEFAIYCTSEFLSMGAGDGHYGLLCDDGLLHGVSNPCQTYGNEVLSKEGKKFSIVALEVWRVG-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :* :: :*.* : * * : ..* ::. ** . ::::.* . :*** :. .:: .. : *.** :::.: :. : ::* * : : . * :*.*.*.:.* * .* :* . * *:.* *: . :.* : :* ", "identical_positions": 31, "similar_positions": 62, "identity": "2.2%" }, { "cls_id": "homologset.agr.FB:FBgn0013672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05504-1", "uniprot_id": "ATP6_RAT", "id": "P05504-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFITPTMMGLPIVVTIIMFPSILFPSSERLISN-------RLHSFQHWLIKLIIKQMMLIHTPKGRT-WALMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVILGFRHKLKNSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMDISPPTATITFI---ILLLLTVLEFAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00848-1", "uniprot_id": "ATP6_MOUSE", "id": "P00848-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFITPTMMGFPIVVAIIMFPSILFPSSKRLINN-------RLHSFQHWLVKLIIKQMMLIHTPKGRT-WTLMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVITGFRHKLKSSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMNISPPTATITFI---ILLLLTILEFAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00846-1", "uniprot_id": "ATP6_HUMAN", "id": "P00846-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFIAPTILGLPAAVLIILFPPLLIPTSKYLINN-------RLITTQQWLIKLTSKQMMTMHNTKGRT-WSLMLVSLIIFIATTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGTVIMGFRSKIKNALAHFLPQGTPTPLIPMLVIIETISLLIQPMALAVRLTANITAGHLLMHLIGSATLAMSTINLPSTLIIFT---ILILLTILEIAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00850-1", "uniprot_id": "ATP6_DROME", "id": "P00850-1", "name": "ATP synthase subunit a", "aln": "-------------------MMTNLFSVFDPSAIFNFSLNWLSTFLGLLMIPSIYWLMPS-------RYNIMWNSILLTLHKEFKTLLGPSGHNGSTFIFISLFSLILFNNFMGLFPYIFTSTSHLTLTLSLALPLWLCFMLYGWINHTQHMFAHLVPQGTPAILMPFMVCIETISNIIRPGTLAVRLTANMIAGHLLLTLLGNTGPSMSYI---LVTFLLM---AQIALLVLESAVAMIQSYVFAVLSTLYSSEVN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00854-1", "uniprot_id": "ATP6_YEAST", "id": "P00854-1", "name": "ATP synthase subunit a", "aln": "MFNLLNTYITSPLDQFEIRTLFGLQSSFIDLSCLNLTTFSLYTIIVLLVITSLYTLTNNNNKIIGSRWLISQEAIYDTIMNMTKGQIGGKNWGLYFPMIFTLFMFIFIANLISMIPYSFALSAHLVFIISLSIVIWLGNTILGLYKHGWVFFSLFVPAGTPLPLVPLLVIIETLSYFARAISLGLRLGSNILAGHLLMVILAGLTFNFMLINLFTLVFGFVPLAMILAIMMLEFAIGIIQGYVWAILTASYLKDAVYLH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : * : :.:. :: :::.: * . * . : : .. ::.:*: :* *::.::*: *: :::* : ::::: :* : * : :: ::* *** *:*::: ***:* : :. :*.:** :*: *****: ::.. : * : : : : :** *:.:**.**:::* : * : ", "identical_positions": 41, "similar_positions": 82, "identity": "15.83%" }, { "cls_id": "homologset.agr.FB:FBgn0013674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05503-1", "uniprot_id": "COX1_RAT", "id": "P05503-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MLVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------GNIKWSPAMLWALGFIFLFTVGG--------------------------------------------------------LTGIVLSN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMAGFVHWFPLFSGYTLN-DTWAKAHFAIMFVGVNMTFFPQHFLG-LAGMPRRYSDYPDAYTTWN----TVSSMGSFIS-----------LTAVLVMIFMIWEAFAS-------KREVLSISY---------------SSTNLEWLHGCPPPYHTFEEPSYVKVK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00397-1", "uniprot_id": "COX1_MOUSE", "id": "P00397-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------GNIKWSPAMLWALGFIFLFTVGG--------------------------------------------------------LTGIVLSN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMAGFVHWFPLFSGFTLD-DTWAKAHFAIMFVGVNMTFFPQHFLG-LSGMPRRYSDYPDAYTTWN----TVSSMGSFIS-----------LTAVLIMIFMIWEAFAS-------KREVMSVSY---------------ASTNLEWLHGCPPPYHTFEEPTYVKVK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00395-1", "uniprot_id": "COX1_HUMAN", "id": "P00395-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------SNMKWSAAVLWALGFIFLFTVGG--------------------------------------------------------LTGIVLAN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMGGFIHWFPLFSGYTLD-QTYAKIHFTIMFIGVNLTFFPQHFLG-LSGMPRRYSDYPDAYTTWN----ILSSVGSFIS-----------LTAVMLMIFMIWEAFAS-------KRKVLMVEE---------------PSMNLEWLYGCPPPYHTFEEPVYMKS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY8-1", "uniprot_id": "COX1_DANRE", "id": "Q9MIY8-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MTITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPILIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTTINMKPPTISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMG-MVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------GAIKWETPMLWALGFIFLFTVGG--------------------------------------------------------LTGIVLAN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMAGFVHWFPLFTGYTLN-SVWTKIHFGVMFIGVNLTFFPQHFLG-LAGMPRRYSDYPDAYALWN----TVSSIGSLIS-----------LVAVIMFLFILWEAFTA-------KREVLSVEL---------------TATNVEWLHGCPPPYHTFEEPAFVQIQSN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00399-1", "uniprot_id": "COX1_DROME", "id": "P00399-1", "name": "Cytochrome c oxidase subunit 1", "aln": "--SRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGA--LIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLG-MIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSAT--MIIAVPTGIKIFSWLATLHG------------------TQLSYSPAILWALGFVFLFTVGG--------------------------------------------------------LTGVVLAN------SSVDIILHDTYYVVAHFHYVLSMG--------AVFAIMAGFIHWYPLFTGLTLN-NKWLKSHFIIMFIGVNLTFFPQHFLG-LAGMPRRYSDYPDAYTTWN----IVSTIGSTIS-----------LLGILFFFFIIWESLVS-------QRQVIYPIQ---------------LNSSIEWYQNTPPAEHSYSELPLLTN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00401-1", "uniprot_id": "COX1_YEAST", "id": "P00401-1", "name": "Cytochrome c oxidase subunit 1", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYS-KKPVFGEIS-MVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSAT--MIIAIPTGIKIFSWLATIHG------------------GSIRLATPMLYAIAFLFLFTMGG--------------------------------------------------------LTGVALAN------ASLDVAFHDTYYVVGHFHYVLSMG--------AIFSLFAGYYYWSPQILGLNYN-EKLAQIQFWLIFIGANVIFFPMHFLG-INGMPRRIPDYPDAFAGWN----YVASIGSFIA-----------TLSLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9ZZX1-1", "uniprot_id": "SCE4_YEAST", "id": "Q9ZZX1-1", "name": "Intron-encoded DNA endonuclease aI5 alpha", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYS-KKPVFGEIS-MVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSAT--MIIAIPTGIKIFSWLMNPFSKDKNKNKNKKLIRNYQKMNNNNMMKTYLNNNNMIMMNMYKGNLYDIYPRSNRNYIQPNNINKELVVYGYNLESCVGMPTYTNIVKHMVGIPNNILYIMTGILLTDGWIDYTSKKDLDKKTIMEINCRFRLKQSMIH--SEYLMYVFMLLSHYCMSYPKMKIAKVKGKSYNQLEFYTRSLPCFTILRYMFYNGRVKIVPNNLYDLLNYESLAH----MIMCDGSFVKGGGLYLNLQSFTTKELIFIMNILKIKFNLNCTLHKSRNKYTIYMR---------VESVKRLFPMIYKYILPSMRYKFDIMLWQKKYNMIN--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P03878-1", "uniprot_id": "SCE2_YEAST", "id": "P03878-1", "name": "Intron-encoded DNA endonuclease aI4", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGQTVATIIMLMMYNDMHFSKCWKLLKKWITNIMSTLFKALFVKMFMSYNNQQDKMMNNTMLKKDNIKRSSETTRKMLNNSMNKKFNQWLAGLIDGDGYFG----------IVSKKYVSLEITVALEDEMALKEIQN------------------------------------------------------KFGGSIKLR------SGVKAIRYRLTNKTGMIKLINAVNGNIRNTKRLVQFNKVCILLGIDFIYPIKLTKDNSWFVGFFDADGTINYSFKNNHPQLTISVTNKYLQDVQEYKNILGGNIYFDKSQNGYYK----------WSIQSKDMVLNFINDYIKMNPSRTTKMNKLYLSK---------------EFYNLKELKAYNKSSDSMQYKAWLNFENKWKNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*** ***..**:::. ::*: **::*::** **. ** * *:.:::**:*..**.:****:*** :******:*:***:**.* ****:**::**:** .: *:.*: ** ************:. :* *.****:**:***:.:**:***:***.* :**:. :: : *****::.:**.*********:..***** ***:**:**: :********:*******:. . *::: :. : . ** . :. :. *: ::.: .:* : . . :* * :: . . *. .** . : : * : . :: :: : : . . * : . : . * : .. :. : . . . : . . ", "identical_positions": 150, "similar_positions": 134, "identity": "23.01%" }, { "cls_id": "homologset.agr.FB:FBgn0013675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00406-1", "uniprot_id": "COX2_RAT", "id": "P00406-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYIISLMLTTKLTH----TSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYED-----LCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00405-1", "uniprot_id": "COX2_MOUSE", "id": "P00405-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTH----TSTMDAQEVETIWTILPAVILIMIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYED-----LCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00403-1", "uniprot_id": "COX2_HUMAN", "id": "P00403-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MAHAAQVGLQDATSPIMEELITFHDHALMIIFLICFLVLYALFLTLTTKLTN----TNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEVNDPSLTIKSIGHQWYWTYEYTDYGG-----LIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00408-1", "uniprot_id": "COX2_DROME", "id": "P00408-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MSTWANLGLQDSASPLMEQLIFFHDHALLILVMITVLVGYLMFMLFFNNYVN----RFLLHGQLIEMIWTILPAIILLFIALPSLRLLYLLDEINEPSVTLKSIGHQWYWSYEYSDFNN-----IEFDSYMIPTNELMTDGFRLLDVDNRVVLPMNSQIRILVTAADVIHSWTVPALGVKVDGTPGRLNQTNFFINRPGLFYGQCSEICGANHSFMPIVIESVPVNYFIKWISSNNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00410-1", "uniprot_id": "COX2_YEAST", "id": "P00410-1", "name": "Cytochrome c oxidase subunit 2", "aln": "MLDLLRLQLTTFIMNDVPTPYACYFQDSATPNQEGILELHDNIMFYLLVILGLVSWMLYTIVMTYSKNPIAYKYIKHGQTIEVIWTIFPAVILLIIAFPSFILLYLCDEVISPAMTIKAIGYQWYWKYEYSDFINDSGETVEFESYVIPDELLEEGQLRLLDTDTSMVVPVDTHIRFVVTAADVIHDFAIPSLGIKVDATPGRLNQVSALIQREGVFYGACSELCGTGHANMPIKIEAVSLPKFLEWLNEQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :**:::* * : :**: :: :.:* ** : : . . : ..* :* :***:**:**::**:**: :**: **: .* :*:*::*:****.***:*: . : *:**::* * . :***:.*. :*:*:: **::::: **:*.:::*:**:*.*. ******.. * *::** ***:**:.*: *** :* :.: * ", "identical_positions": 80, "similar_positions": 81, "identity": "31.62%" }, { "cls_id": "homologset.agr.FB:FBgn0013676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05505-1", "uniprot_id": "COX3_RAT", "id": "P05505-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQTHAYHMVNPSPWPLTG--ALSALLLTSGLVMWFHYNSTILLSLGLLTNILTMYQWWRDIIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMNQALLITILLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00416-1", "uniprot_id": "COX3_MOUSE", "id": "P00416-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQTHAYHMVNPSPWPLTG--AFSALLLTSGLVMWFHYNSITLLTLGLLTNILTMYQWWRDVIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGISPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGKRNHMNQALLITIMLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00414-1", "uniprot_id": "COX3_HUMAN", "id": "P00414-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQSHAYHMVKPSPWPLTG--ALSALLMTSGLAMWFHFHSMTLLMLGLLTNTLTMYQWWRDVTRESTYQGHHTPPVQKGLRYGMILFITSEVFFFAGFFWAFYHSSLAPTPQLGGHWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMENNRNQMIQALLITILLGLYFTLLQASEYFESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY4-1", "uniprot_id": "COX3_DANRE", "id": "Q9MIY4-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MAHQAHAYHMVDPSPWPLTG--AVAALLMSSGLAIWFHLHSMTLIVLGMILLILTMIQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGLTTLDPFEVPLLNTAVLLASGVTVTWAHHSLMEGERKQAIQSLALTILLGLYFTALQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAVCLLRQVLFHFTSDHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00417-1", "uniprot_id": "COX3_DROME", "id": "P00417-1", "name": "Cytochrome c oxidase subunit 3", "aln": "-----MSTHSNHPFHLVDYSPWPLTG--AIGAMTTVSGMVKWFHQYDISLFVLGNIITILTVYQWWRDVSREGTYQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLNTAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSIYGSTFFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWWGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00420-1", "uniprot_id": "COX3_YEAST", "id": "P00420-1", "name": "Cytochrome c oxidase subunit 3", "aln": "MTHLERSRHQQHPFHMVMPSPWPIVVSFALLSLALSTALTMHGYIGNMNMVYLALFVLLTSSILWFRDIVAEATYLGDHTMAVRKGINLGFLMFVLSEVLIFAGLFWAYFHSAMSPDVTLGACWPPVGIEAVQPTELPLLNTIILLSSGATVTYSHHALIAGNRNKALSGLLITFWLIVIFVTCQYIEYTNAAFTISDGVYGSVFYAGTGLHFLHMVMLAAMLGVNYWRMRNYHLTAGHHVGYETTIIYTHVLDVIWLFLYVVFYWWGV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *.:*:* ****:. *. :: :.:. : . :. *. : : *:**: *.*: * ** * *:. *:::*: ***::* .:***::**:: * **. *** *: ..:* ::***** :**:**.::*::**:*: .::.: ..* :*. * : *. * ** ::.*:*:*.:***.*: .**:* :*::: :::* : * *:: **.*:*:: * *.:**:*****: :**** ", "identical_positions": 90, "similar_positions": 95, "identity": "33.46%" }, { "cls_id": "homologset.agr.FB:FBgn0013678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00159-1", "uniprot_id": "CYB_RAT", "id": "P00159-1", "name": "Cytochrome b", "aln": "-MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYTFLET--WNIGIILLFAVMATAFMGYVLPWGQMSFWG-ATVITNLLSAIPYIGTTLVEWIWGG---------FSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVFMLLLFLMT-----LVLFFPDLLGDPDNYTPANPLNTPPH--------IKPEWYFL---FAYAILRSIP------------------NKLGGVVALILSILILAFLPFLHTSKQRSL--------------------TFRPITQILYWILVAN-------LLILTWIG-------------------------------------GQPVEHPF-----------------------------------------IIIGQLAS---ISYFSIILILM------PISGIVEDKMLKWN-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00158-1", "uniprot_id": "CYB_MOUSE", "id": "P00158-1", "name": "Cytochrome b", "aln": "-MTNMRKTHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTFMET--WNIGVLLLFAVMATAFMGYVLPWGQMSFWG-ATVITNLLSAIPYIGTTLVEWIWGG---------FSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDILGILIMFLILMT-----LVLFFPDMLGDPDNYMPANPLNTPPH--------IKPEWYFL---FAYAILRSIP------------------NKLGGVLALILSILILALMPFLHTSKQRSL--------------------MFRPITQILYWILVAN-------LLILTWIG-------------------------------------GQPVEHPF-----------------------------------------IIIGQLAS---ISYFSIILILM------PISGIIEDKMLKLYP------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00156-1", "uniprot_id": "CYB_HUMAN", "id": "P00156-1", "name": "Cytochrome b", "aln": "-MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFLYSET--WNIGIILLLATMATAFMGYVLPWGQMSFWG-ATVITNLLSAIPYIGTDLVQWIWGG---------YSVDSPTLTRFFTFHFILPFIIAALATLHLLFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLMT-----LTLFSPDLLGDPDNYTLANPLNTPPH--------IKPEWYFL---FAYTILRSVP------------------NKLGGVLALLLSILILAMIPILHMSKQQSM--------------------MFRPLSQSLYWLLAAD-------LLILTWIG-------------------------------------GQPVSYPF-----------------------------------------TIIGQVAS---VLYFTTILILM------PTISLIENKMLKWA-------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18935-1", "uniprot_id": "CYB_DROME", "id": "P18935-1", "name": "Cytochrome b", "aln": "MNKPLRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTPT--WLIGVIILFLVMGTAFMGYVLPWGQMSFWG-ATVITNLLSAIPYLGMDLVQWLWGG---------FAVDNATLTRFFTFHFILPFIVLAMTMIHLLFLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILIS-----LVLISPNLLGDPDNFIPANPLVTPAH--------IQPEWYFL---FAYAILRSIP------------------NKLGGVIALVLSIAILMILPFYNLSKFRGI--------------------QFYPINQVMFWSMLVT-------VILLTWIG-------------------------------------ARPVEEPY-----------------------------------------VLIGQILT---VVYFLYYLVN-------PLITKWWDNLLN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00163-1", "uniprot_id": "CYB_YEAST", "id": "P00163-1", "name": "Cytochrome b", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWG-ATVITNLFSAIPFVGNDIVSWLWGG---------FSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILAL-----FVFYSPNTLGHPDNYIPGNPLVTPAS--------IVPEWYLL---PFYAILRSIP------------------DKLLGVITMFAAILVLLVLPFTDRSVVRGN--------------------TFKVLSKFFFFIFVFN-------FVLLGQIG-------------------------------------ACHVEVPY-----------------------------------------VLMGQIAT---FIYFAYFLIIV------PVISTIENVLFY------------------------IGRVNK---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P03879-1", "uniprot_id": "MBI4_YEAST", "id": "P03879-1", "name": "Intron-encoded RNA maturase bI4", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWG-ATVITNLFSAIPFVGNDIVSWLWGG---------FSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILAL-----FVFYSPNTLGQNMALLLITYVINILCAVCWKSLFIKYQWKIYNKTTYYFIIQNILNTKQLNNFVLKFNWTKQYNKMNIVSDLFNPNRVKYYYKEDNQQVTNMNSSNTHLTSNKKNLLVDTSETTRTTKNKFNYLLNIFN-------MKKMNQIITKRHYSIYKDSNIRFNQWLAGLIDGDGYFCITKNKYASCEITVELKDEKMLRQIQDKFGGSVKLRSGVKAIRYRLQNKEGMIKLINAVNGNIRNSKRLVQFNKVCILLNIDFKEPIKLTKDNAWFMGFFDADGTINYYYSGKLKIRPQLTISVTNKYLHDVEYYREVFGGNIYFDKAKNGYFKWSINNKELHNIFYTYNKSCPSKSNKGKRLFLIDKFYYLYDLLAFKAPHNTALYKAWLKFNEKWNNN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P03873-1", "uniprot_id": "MBI2_YEAST", "id": "P03873-1", "name": "Cytochrome b mRNA maturase bI2", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGNMNIASNMF--------------------------NMMKT---------IYMMMLMLLIYIFYTIMMRQMMKTKEYTMLIKSMDYINKNKYM-INLNMTNKKDMNNNIG-----PLNMN--ILSIIYGSMLGDGHAEKRKGGK--GTRIVFQQEYCNINYLYYLHSLLANLGYCN-----------TNLPLIKTRLGKKGKIRQYLKFNTWT-----------------------YDSFNMIYSEWY---------IKNMSGKGN----------------------------------------IKVIPKSLD--------------------------------------------NYLTPLALAIWIMDDGCKLG---KGL--KFTTNCFSYKD-------------VQYLTYLLHNKYNIKSTITKGNKENTQFVIYVWKESMPILTKIVSPYIIPSMKY----KLGNYL-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9ZZW7-1", "uniprot_id": "MBI3_YEAST", "id": "Q9ZZW7-1", "name": "Cytochrome b mRNA maturase bI3", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWG-ATVITNLFSAIPFVGNDIVSWLWGGFNMEDPYYSNMMLNKSVLCWNIFIWMMNYYIIQLIIYNNMIWNKNNMVKMFIMRRKLAVINMYMYMKLIIQRTYSYYMNNTIIYDKNHKLNTDNPIYAYIGGLFEGDGWITISKKGKYLLYELGIEMHIRDIQLLYKIKNILG-----------------IGKVTIKKLKMKDGTIKEMCKFNVRNKNHLKN------------IIIPIFDKYPMLTNKHYDYLYFKDNLLKDIKYYND----------------------------------------LSYYLRPIKPFNTTE---------------------------------DILNKNYFSSWLIGFFEAESCFSIY---KPMNKKMKTASFEVSQNNSMEVMLAIKSYLKITQNIYTDKFNNSRMTTKSINGIKNVVMFINNNPIKLLGYKKLQYLLFLKDLRTITKYNNYFKIPPKY-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: :.: * ::* * * .*. ***:***** **::** **:*:****:.: ** *: ** ***: *:::* :******:**: :::*:.:*:****: . * :*::::: .:.***:** :****.** .: :*:: : . ::: : : : : : * * : : . : : * : : . : . : : . . : : ", "identical_positions": 66, "similar_positions": 79, "identity": "9.97%" }, { "cls_id": "homologset.agr.FB:FBgn0013679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03889-1", "uniprot_id": "NU1M_RAT", "id": "P03889-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MYFINILTLLIPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWIPLPMPHPLINLNLGMLFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMSGSFSLQMLITTQEHIWLLIPAWPMAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTSIVFLGPLYHINYPELYSTSFMTETLLLSTTFLWIRASYPRFRYDQLMHLLWKNFLPLTLAFCMWYISLPIFLAGIPPYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03888-1", "uniprot_id": "NU1M_MOUSE", "id": "P03888-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MFFINILTLLVPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWVPLPMPHPLINLNLGILFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMNGSYSLQTLITTQEHMWLLLPAWPMAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTTIIFLGPLYYINLPELYSTNFMMEALLLSSTFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHISLPIFTAGVPPYM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03886-1", "uniprot_id": "NU1M_HUMAN", "id": "P03886-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MPMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPLKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITTQEHLWLLLPSWPLAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTIFLGTTYDALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALLMWYVSMPITISSIPPQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIZ0-1", "uniprot_id": "NU1M_DANRE", "id": "Q9MIZ0-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "MLDILTSHLINPLAYAVPVLIAVAFLTLVERKVLGYMQLRKGPNVMGPRGLLQSVADGVKLFIKEPIRPSMASPILFLTAPVLALILAMMLWAPMPMPYPVLDLNLGILFIMAISSLAVYSILGSGWASNSKYALIGALRAVAQTISYEVSLGLILLSAVIFSGGYTLQTFNTTQEDTWLLLPLWPLAIMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYSNILLMNTHSTVLFLGASFTPDAPELMTISIATKTAMLSILFLWMRASYPRFRYDQLMHLIWKNFLPITLVLVLWHIALPIALAGLPPQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18929-1", "uniprot_id": "NU1M_DROME", "id": "P18929-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "--MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALILLSFIFLIGSYNMIYFFFYQVYMWFLIILFPMALVWMSISLAETNRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFLG-------CDVFNLLFYMKLTFISFVFIWVRGTLPRFRYDKLMYLAWKCFLSFSLNYLLFFIGFKILLFSLL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : :*:::*** * ***:***:*:***** :* *: *...*.:*** ** * :. : :* ::* ::: :* :*: : .:*** **::. :**.**::: :**:***:*:*:*.************::.:**** ::: *.:.: : * *:*: :*:*::* :******:***::***********:**::* ***:*:***:.*::*. :*** :: . : : ::: *:*:* : ******:**:* ** **.::* ::.:.: * .: ", "identical_positions": 125, "similar_positions": 103, "identity": "38.58%" } ]