{
    "uniprot_canonical_ac": "A0A0R4ILB2-1",
    "uniprot_id": [
        {
            "id": "FLC2A_DANRE",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILB2",
            "type": "external"
        }
    ],
    "mass": 51800.0,
    "length": 470,
    "protein_name": "Choline/ethanolamine transporter flvcr2a",
    "gene_name": "flvcr2a",
    "organism": "Zebrafish",
    "refseq_name": "",
    "refseq_ac": [],
    "gene_names_uniprotkb": "flvcr2a; Mfsd7c-a",
    "gene_names_refseq": "",
    "protein_names_uniprotkb": "Choline/ethanolamine transporter flvcr2a; Feline leukemia virus subgroup C receptor-related protein 2 homolog A; Heme transporter flvcr2a; Major facilitator superfamily domain containing 7C-a",
    "protein_names_refseq": "",
    "tax_id": 7955,
    "disease": "proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Disease Ontology:DOID:0111666)",
    "pathway": " (dre:565210)",
    "pathway_count": 1,
    "publication_count": 2,
    "publication_id_list": "23594743;38302740",
    "function": "Choline uniporter that specifically mediates choline uptake at the blood-brain-barrier (PubMed:38302740). Responsible for the majority of choline uptake across the blood-brain-barrier from the circulation into the brain (By similarity). Choline, a nutrient critical for brain development, is a precursor of phosphatidylcholine, as well as betaine (By similarity). Also mediates transport of ethanolamine (By similarity). Choline and ethanolamine transport is not coupled with proton transport and is exclusively driven by the choline gradient across the plasma membrane (By similarity). Also acts as a heme b transporter (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 1,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "A0A8N7TF83",
    "ec_number_list": [],
    "go_molecular_function": "GO:0015232 heme transmembrane transporter activity;GO:0020037 heme binding;GO:0015220 choline transmembrane transporter activity;GO:0034228 ethanolamine transmembrane transporter activity",
    "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane",
    "go_biological_process": "GO:0097037 heme export;GO:0150104 transport across blood-brain barrier",
    "synthesized_glycan_count": 0,
    "hit_score": 0.3,
    "record_id": "A0A0R4ILB2-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000000001.00000.000"
}
