{
    "uniprot_canonical_ac": "A0A0G2K628-1",
    "uniprot_id": [
        {
            "id": "A0A0G2K628_RAT",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K628",
            "type": "external"
        }
    ],
    "mass": 80316.0,
    "length": 727,
    "protein_name": "Ski oncogene",
    "gene_name": "Ski",
    "organism": "Rat",
    "refseq_name": "ski oncogene",
    "refseq_ac": [
        {
            "id": "NP_001094185",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094185",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "Ski",
    "gene_names_refseq": "RGD1565591; Ski; c-ski",
    "protein_names_uniprotkb": "Ski oncogene; Proto-oncogene c-Ski",
    "protein_names_refseq": "Sloan-Kettering viral oncogene homolog; ski oncogene; ski sarcoma viral oncogene homolog; v-ski avian sarcoma viral oncogene homolog",
    "tax_id": 10116,
    "disease": "craniosynostosis (Disease Ontology:DOID:2340)",
    "pathway": " (R-RNO-201451);  (R-RNO-2173795)",
    "pathway_count": 2,
    "publication_count": 6,
    "publication_id_list": "22673903;30488595;33349993;33847835;35007896;35339646",
    "function": "SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation. Publication Status: Online-Only, [RefSeq, PubMed]; Ski Regulates the Inflammatory Response of Reactive Astrocytes Induced by Oxygen Glucose Deprivation/Reoxygenation (OGD/R) Through the NF-kappaB Pathway., [RefSeq, PubMed]; Ski overexpression elevates expression and extracellular secretion/release of MMP-9 in primary cardiac myofibroblasts., [RefSeq, PubMed]; Ski promotes proliferation and inhibits apoptosis in fibroblasts under high-glucose conditions via the FoxO1 pathway., [RefSeq, PubMed]; Ski regulates proliferation and migration of reactive astrocytes induced by lipopolysaccharide (LPS) through PI3K/Akt pathway., [RefSeq, PubMed]",
    "predicted_glycosites": 1,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 1,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 1,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 1,
    "glyco_site_count": 1,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0046811 histone deacetylase inhibitor activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding",
    "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0017053 transcription repressor complex;GO:0005667 transcription regulator complex",
    "go_biological_process": "GO:0043585 nose morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030326 embryonic limb morphogenesis",
    "synthesized_glycan_count": 0,
    "hit_score": 0.7,
    "record_id": "A0A0G2K628-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000001000.00010.001"
}